data_3L4X # _entry.id 3L4X # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3L4X RCSB RCSB056837 WWPDB D_1000056837 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3L4T . unspecified PDB 3L4U . unspecified PDB 3L4V . unspecified PDB 3L4W . unspecified PDB 3L4Y . unspecified PDB 3L4Z . unspecified # _pdbx_database_status.entry_id 3L4X _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2009-12-21 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sim, L.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. ; _citation.journal_abbrev Biochemistry _citation.journal_volume 49 _citation.page_first 443 _citation.page_last 451 _citation.year 2010 _citation.journal_id_ASTM BICHAW _citation.country US _citation.journal_id_ISSN 0006-2960 _citation.journal_id_CSD 0033 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20039683 _citation.pdbx_database_id_DOI 10.1021/bi9016457 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Sim, L.' 1 primary 'Jayakanthan, K.' 2 primary 'Mohan, S.' 3 primary 'Nasi, R.' 4 primary 'Johnston, B.D.' 5 primary 'Pinto, B.M.' 6 primary 'Rose, D.R.' 7 # _cell.length_a 87.173 _cell.length_b 109.437 _cell.length_c 109.327 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3L4X _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3L4X _symmetry.Int_Tables_number 19 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Maltase-glucoamylase, intestinal' 99276.742 1 '3.2.1.20, 3.2.1.3' ? 'UNP residues 87-954' ? 2 non-polymer syn ;(1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; 424.442 1 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 4 non-polymer syn GLYCEROL 92.094 4 ? ? ? ? 5 water nat water 18.015 613 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Maltase, Alpha-glucosidase, Glucoamylase, Glucan 1,4-alpha-glucosidase' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAHHHHHH ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 ALA n 1 3 GLU n 1 4 CYS n 1 5 PRO n 1 6 VAL n 1 7 VAL n 1 8 ASN n 1 9 GLU n 1 10 LEU n 1 11 GLU n 1 12 ARG n 1 13 ILE n 1 14 ASN n 1 15 CYS n 1 16 ILE n 1 17 PRO n 1 18 ASP n 1 19 GLN n 1 20 PRO n 1 21 PRO n 1 22 THR n 1 23 LYS n 1 24 ALA n 1 25 THR n 1 26 CYS n 1 27 ASP n 1 28 GLN n 1 29 ARG n 1 30 GLY n 1 31 CYS n 1 32 CYS n 1 33 TRP n 1 34 ASN n 1 35 PRO n 1 36 GLN n 1 37 GLY n 1 38 ALA n 1 39 VAL n 1 40 SER n 1 41 VAL n 1 42 PRO n 1 43 TRP n 1 44 CYS n 1 45 TYR n 1 46 TYR n 1 47 SER n 1 48 LYS n 1 49 ASN n 1 50 HIS n 1 51 SER n 1 52 TYR n 1 53 HIS n 1 54 VAL n 1 55 GLU n 1 56 GLY n 1 57 ASN n 1 58 LEU n 1 59 VAL n 1 60 ASN n 1 61 THR n 1 62 ASN n 1 63 ALA n 1 64 GLY n 1 65 PHE n 1 66 THR n 1 67 ALA n 1 68 ARG n 1 69 LEU n 1 70 LYS n 1 71 ASN n 1 72 LEU n 1 73 PRO n 1 74 SER n 1 75 SER n 1 76 PRO n 1 77 VAL n 1 78 PHE n 1 79 GLY n 1 80 SER n 1 81 ASN n 1 82 VAL n 1 83 ASP n 1 84 ASN n 1 85 VAL n 1 86 LEU n 1 87 LEU n 1 88 THR n 1 89 ALA n 1 90 GLU n 1 91 TYR n 1 92 GLN n 1 93 THR n 1 94 SER n 1 95 ASN n 1 96 ARG n 1 97 PHE n 1 98 HIS n 1 99 PHE n 1 100 LYS n 1 101 LEU n 1 102 THR n 1 103 ASP n 1 104 GLN n 1 105 THR n 1 106 ASN n 1 107 ASN n 1 108 ARG n 1 109 PHE n 1 110 GLU n 1 111 VAL n 1 112 PRO n 1 113 HIS n 1 114 GLU n 1 115 HIS n 1 116 VAL n 1 117 GLN n 1 118 SER n 1 119 PHE n 1 120 SER n 1 121 GLY n 1 122 ASN n 1 123 ALA n 1 124 ALA n 1 125 ALA n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 TYR n 1 130 GLN n 1 131 VAL n 1 132 GLU n 1 133 ILE n 1 134 SER n 1 135 ARG n 1 136 GLN n 1 137 PRO n 1 138 PHE n 1 139 SER n 1 140 ILE n 1 141 LYS n 1 142 VAL n 1 143 THR n 1 144 ARG n 1 145 ARG n 1 146 SER n 1 147 ASN n 1 148 ASN n 1 149 ARG n 1 150 VAL n 1 151 LEU n 1 152 PHE n 1 153 ASP n 1 154 SER n 1 155 SER n 1 156 ILE n 1 157 GLY n 1 158 PRO n 1 159 LEU n 1 160 LEU n 1 161 PHE n 1 162 ALA n 1 163 ASP n 1 164 GLN n 1 165 PHE n 1 166 LEU n 1 167 GLN n 1 168 LEU n 1 169 SER n 1 170 THR n 1 171 ARG n 1 172 LEU n 1 173 PRO n 1 174 SER n 1 175 THR n 1 176 ASN n 1 177 VAL n 1 178 TYR n 1 179 GLY n 1 180 LEU n 1 181 GLY n 1 182 GLU n 1 183 HIS n 1 184 VAL n 1 185 HIS n 1 186 GLN n 1 187 GLN n 1 188 TYR n 1 189 ARG n 1 190 HIS n 1 191 ASP n 1 192 MET n 1 193 ASN n 1 194 TRP n 1 195 LYS n 1 196 THR n 1 197 TRP n 1 198 PRO n 1 199 ILE n 1 200 PHE n 1 201 ASN n 1 202 ARG n 1 203 ASP n 1 204 THR n 1 205 THR n 1 206 PRO n 1 207 ASN n 1 208 GLY n 1 209 ASN n 1 210 GLY n 1 211 THR n 1 212 ASN n 1 213 LEU n 1 214 TYR n 1 215 GLY n 1 216 ALA n 1 217 GLN n 1 218 THR n 1 219 PHE n 1 220 PHE n 1 221 LEU n 1 222 CYS n 1 223 LEU n 1 224 GLU n 1 225 ASP n 1 226 ALA n 1 227 SER n 1 228 GLY n 1 229 LEU n 1 230 SER n 1 231 PHE n 1 232 GLY n 1 233 VAL n 1 234 PHE n 1 235 LEU n 1 236 MET n 1 237 ASN n 1 238 SER n 1 239 ASN n 1 240 ALA n 1 241 MET n 1 242 GLU n 1 243 VAL n 1 244 VAL n 1 245 LEU n 1 246 GLN n 1 247 PRO n 1 248 ALA n 1 249 PRO n 1 250 ALA n 1 251 ILE n 1 252 THR n 1 253 TYR n 1 254 ARG n 1 255 THR n 1 256 ILE n 1 257 GLY n 1 258 GLY n 1 259 ILE n 1 260 LEU n 1 261 ASP n 1 262 PHE n 1 263 TYR n 1 264 VAL n 1 265 PHE n 1 266 LEU n 1 267 GLY n 1 268 ASN n 1 269 THR n 1 270 PRO n 1 271 GLU n 1 272 GLN n 1 273 VAL n 1 274 VAL n 1 275 GLN n 1 276 GLU n 1 277 TYR n 1 278 LEU n 1 279 GLU n 1 280 LEU n 1 281 ILE n 1 282 GLY n 1 283 ARG n 1 284 PRO n 1 285 ALA n 1 286 LEU n 1 287 PRO n 1 288 SER n 1 289 TYR n 1 290 TRP n 1 291 ALA n 1 292 LEU n 1 293 GLY n 1 294 PHE n 1 295 HIS n 1 296 LEU n 1 297 SER n 1 298 ARG n 1 299 TYR n 1 300 GLU n 1 301 TYR n 1 302 GLY n 1 303 THR n 1 304 LEU n 1 305 ASP n 1 306 ASN n 1 307 MET n 1 308 ARG n 1 309 GLU n 1 310 VAL n 1 311 VAL n 1 312 GLU n 1 313 ARG n 1 314 ASN n 1 315 ARG n 1 316 ALA n 1 317 ALA n 1 318 GLN n 1 319 LEU n 1 320 PRO n 1 321 TYR n 1 322 ASP n 1 323 VAL n 1 324 GLN n 1 325 HIS n 1 326 ALA n 1 327 ASP n 1 328 ILE n 1 329 ASP n 1 330 TYR n 1 331 MET n 1 332 ASP n 1 333 GLU n 1 334 ARG n 1 335 ARG n 1 336 ASP n 1 337 PHE n 1 338 THR n 1 339 TYR n 1 340 ASP n 1 341 SER n 1 342 VAL n 1 343 ASP n 1 344 PHE n 1 345 LYS n 1 346 GLY n 1 347 PHE n 1 348 PRO n 1 349 GLU n 1 350 PHE n 1 351 VAL n 1 352 ASN n 1 353 GLU n 1 354 LEU n 1 355 HIS n 1 356 ASN n 1 357 ASN n 1 358 GLY n 1 359 GLN n 1 360 LYS n 1 361 LEU n 1 362 VAL n 1 363 ILE n 1 364 ILE n 1 365 VAL n 1 366 ASP n 1 367 PRO n 1 368 ALA n 1 369 ILE n 1 370 SER n 1 371 ASN n 1 372 ASN n 1 373 SER n 1 374 SER n 1 375 SER n 1 376 SER n 1 377 LYS n 1 378 PRO n 1 379 TYR n 1 380 GLY n 1 381 PRO n 1 382 TYR n 1 383 ASP n 1 384 ARG n 1 385 GLY n 1 386 SER n 1 387 ASP n 1 388 MET n 1 389 LYS n 1 390 ILE n 1 391 TRP n 1 392 VAL n 1 393 ASN n 1 394 SER n 1 395 SER n 1 396 ASP n 1 397 GLY n 1 398 VAL n 1 399 THR n 1 400 PRO n 1 401 LEU n 1 402 ILE n 1 403 GLY n 1 404 GLU n 1 405 VAL n 1 406 TRP n 1 407 PRO n 1 408 GLY n 1 409 GLN n 1 410 THR n 1 411 VAL n 1 412 PHE n 1 413 PRO n 1 414 ASP n 1 415 TYR n 1 416 THR n 1 417 ASN n 1 418 PRO n 1 419 ASN n 1 420 CYS n 1 421 ALA n 1 422 VAL n 1 423 TRP n 1 424 TRP n 1 425 THR n 1 426 LYS n 1 427 GLU n 1 428 PHE n 1 429 GLU n 1 430 LEU n 1 431 PHE n 1 432 HIS n 1 433 ASN n 1 434 GLN n 1 435 VAL n 1 436 GLU n 1 437 PHE n 1 438 ASP n 1 439 GLY n 1 440 ILE n 1 441 TRP n 1 442 ILE n 1 443 ASP n 1 444 MET n 1 445 ASN n 1 446 GLU n 1 447 VAL n 1 448 SER n 1 449 ASN n 1 450 PHE n 1 451 VAL n 1 452 ASP n 1 453 GLY n 1 454 SER n 1 455 VAL n 1 456 SER n 1 457 GLY n 1 458 CYS n 1 459 SER n 1 460 THR n 1 461 ASN n 1 462 ASN n 1 463 LEU n 1 464 ASN n 1 465 ASN n 1 466 PRO n 1 467 PRO n 1 468 PHE n 1 469 THR n 1 470 PRO n 1 471 ARG n 1 472 ILE n 1 473 LEU n 1 474 ASP n 1 475 GLY n 1 476 TYR n 1 477 LEU n 1 478 PHE n 1 479 CYS n 1 480 LYS n 1 481 THR n 1 482 LEU n 1 483 CYS n 1 484 MET n 1 485 ASP n 1 486 ALA n 1 487 VAL n 1 488 GLN n 1 489 HIS n 1 490 TRP n 1 491 GLY n 1 492 LYS n 1 493 GLN n 1 494 TYR n 1 495 ASP n 1 496 ILE n 1 497 HIS n 1 498 ASN n 1 499 LEU n 1 500 TYR n 1 501 GLY n 1 502 TYR n 1 503 SER n 1 504 MET n 1 505 ALA n 1 506 VAL n 1 507 ALA n 1 508 THR n 1 509 ALA n 1 510 GLU n 1 511 ALA n 1 512 ALA n 1 513 LYS n 1 514 THR n 1 515 VAL n 1 516 PHE n 1 517 PRO n 1 518 ASN n 1 519 LYS n 1 520 ARG n 1 521 SER n 1 522 PHE n 1 523 ILE n 1 524 LEU n 1 525 THR n 1 526 ARG n 1 527 SER n 1 528 THR n 1 529 PHE n 1 530 ALA n 1 531 GLY n 1 532 SER n 1 533 GLY n 1 534 LYS n 1 535 PHE n 1 536 ALA n 1 537 ALA n 1 538 HIS n 1 539 TRP n 1 540 LEU n 1 541 GLY n 1 542 ASP n 1 543 ASN n 1 544 THR n 1 545 ALA n 1 546 THR n 1 547 TRP n 1 548 ASP n 1 549 ASP n 1 550 LEU n 1 551 ARG n 1 552 TRP n 1 553 SER n 1 554 ILE n 1 555 PRO n 1 556 GLY n 1 557 VAL n 1 558 LEU n 1 559 GLU n 1 560 PHE n 1 561 ASN n 1 562 LEU n 1 563 PHE n 1 564 GLY n 1 565 ILE n 1 566 PRO n 1 567 MET n 1 568 VAL n 1 569 GLY n 1 570 PRO n 1 571 ASP n 1 572 ILE n 1 573 CYS n 1 574 GLY n 1 575 PHE n 1 576 ALA n 1 577 LEU n 1 578 ASP n 1 579 THR n 1 580 PRO n 1 581 GLU n 1 582 GLU n 1 583 LEU n 1 584 CYS n 1 585 ARG n 1 586 ARG n 1 587 TRP n 1 588 MET n 1 589 GLN n 1 590 LEU n 1 591 GLY n 1 592 ALA n 1 593 PHE n 1 594 TYR n 1 595 PRO n 1 596 PHE n 1 597 SER n 1 598 ARG n 1 599 ASN n 1 600 HIS n 1 601 ASN n 1 602 GLY n 1 603 GLN n 1 604 GLY n 1 605 TYR n 1 606 LYS n 1 607 ASP n 1 608 GLN n 1 609 ASP n 1 610 PRO n 1 611 ALA n 1 612 SER n 1 613 PHE n 1 614 GLY n 1 615 ALA n 1 616 ASP n 1 617 SER n 1 618 LEU n 1 619 LEU n 1 620 LEU n 1 621 ASN n 1 622 SER n 1 623 SER n 1 624 ARG n 1 625 HIS n 1 626 TYR n 1 627 LEU n 1 628 ASN n 1 629 ILE n 1 630 ARG n 1 631 TYR n 1 632 THR n 1 633 LEU n 1 634 LEU n 1 635 PRO n 1 636 TYR n 1 637 LEU n 1 638 TYR n 1 639 THR n 1 640 LEU n 1 641 PHE n 1 642 PHE n 1 643 ARG n 1 644 ALA n 1 645 HIS n 1 646 SER n 1 647 ARG n 1 648 GLY n 1 649 ASP n 1 650 THR n 1 651 VAL n 1 652 ALA n 1 653 ARG n 1 654 PRO n 1 655 LEU n 1 656 LEU n 1 657 HIS n 1 658 GLU n 1 659 PHE n 1 660 TYR n 1 661 GLU n 1 662 ASP n 1 663 ASN n 1 664 SER n 1 665 THR n 1 666 TRP n 1 667 ASP n 1 668 VAL n 1 669 HIS n 1 670 GLN n 1 671 GLN n 1 672 PHE n 1 673 LEU n 1 674 TRP n 1 675 GLY n 1 676 PRO n 1 677 GLY n 1 678 LEU n 1 679 LEU n 1 680 ILE n 1 681 THR n 1 682 PRO n 1 683 VAL n 1 684 LEU n 1 685 ASP n 1 686 GLU n 1 687 GLY n 1 688 ALA n 1 689 GLU n 1 690 LYS n 1 691 VAL n 1 692 MET n 1 693 ALA n 1 694 TYR n 1 695 VAL n 1 696 PRO n 1 697 ASP n 1 698 ALA n 1 699 VAL n 1 700 TRP n 1 701 TYR n 1 702 ASP n 1 703 TYR n 1 704 GLU n 1 705 THR n 1 706 GLY n 1 707 SER n 1 708 GLN n 1 709 VAL n 1 710 ARG n 1 711 TRP n 1 712 ARG n 1 713 LYS n 1 714 GLN n 1 715 LYS n 1 716 VAL n 1 717 GLU n 1 718 MET n 1 719 GLU n 1 720 LEU n 1 721 PRO n 1 722 GLY n 1 723 ASP n 1 724 LYS n 1 725 ILE n 1 726 GLY n 1 727 LEU n 1 728 HIS n 1 729 LEU n 1 730 ARG n 1 731 GLY n 1 732 GLY n 1 733 TYR n 1 734 ILE n 1 735 PHE n 1 736 PRO n 1 737 THR n 1 738 GLN n 1 739 GLN n 1 740 PRO n 1 741 ASN n 1 742 THR n 1 743 THR n 1 744 THR n 1 745 LEU n 1 746 ALA n 1 747 SER n 1 748 ARG n 1 749 LYS n 1 750 ASN n 1 751 PRO n 1 752 LEU n 1 753 GLY n 1 754 LEU n 1 755 ILE n 1 756 ILE n 1 757 ALA n 1 758 LEU n 1 759 ASP n 1 760 GLU n 1 761 ASN n 1 762 LYS n 1 763 GLU n 1 764 ALA n 1 765 LYS n 1 766 GLY n 1 767 GLU n 1 768 LEU n 1 769 PHE n 1 770 TRP n 1 771 ASP n 1 772 ASP n 1 773 GLY n 1 774 GLU n 1 775 THR n 1 776 LYS n 1 777 ASP n 1 778 THR n 1 779 VAL n 1 780 ALA n 1 781 ASN n 1 782 LYS n 1 783 VAL n 1 784 TYR n 1 785 LEU n 1 786 LEU n 1 787 CYS n 1 788 GLU n 1 789 PHE n 1 790 SER n 1 791 VAL n 1 792 THR n 1 793 GLN n 1 794 ASN n 1 795 ARG n 1 796 LEU n 1 797 GLU n 1 798 VAL n 1 799 ASN n 1 800 ILE n 1 801 SER n 1 802 GLN n 1 803 SER n 1 804 THR n 1 805 TYR n 1 806 LYS n 1 807 ASP n 1 808 PRO n 1 809 ASN n 1 810 ASN n 1 811 LEU n 1 812 ALA n 1 813 PHE n 1 814 ASN n 1 815 GLU n 1 816 ILE n 1 817 LYS n 1 818 ILE n 1 819 LEU n 1 820 GLY n 1 821 THR n 1 822 GLU n 1 823 GLU n 1 824 PRO n 1 825 SER n 1 826 ASN n 1 827 VAL n 1 828 THR n 1 829 VAL n 1 830 LYS n 1 831 HIS n 1 832 ASN n 1 833 GLY n 1 834 VAL n 1 835 PRO n 1 836 SER n 1 837 GLN n 1 838 THR n 1 839 SER n 1 840 PRO n 1 841 THR n 1 842 VAL n 1 843 THR n 1 844 TYR n 1 845 ASP n 1 846 SER n 1 847 ASN n 1 848 LEU n 1 849 LYS n 1 850 VAL n 1 851 ALA n 1 852 ILE n 1 853 ILE n 1 854 THR n 1 855 ASP n 1 856 ILE n 1 857 ASP n 1 858 LEU n 1 859 LEU n 1 860 LEU n 1 861 GLY n 1 862 GLU n 1 863 ALA n 1 864 TYR n 1 865 THR n 1 866 VAL n 1 867 GLU n 1 868 TRP n 1 869 ALA n 1 870 HIS n 1 871 HIS n 1 872 HIS n 1 873 HIS n 1 874 HIS n 1 875 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'MGA, MGAM, MGAML' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMT-BiP-V5-His _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MGA_HUMAN _struct_ref.pdbx_db_accession O43451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW ; _struct_ref.pdbx_align_begin 87 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3L4X _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 868 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O43451 _struct_ref_seq.db_align_beg 87 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 954 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 868 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3L4X ASP A 772 ? UNP O43451 ASN 858 VARIANT 772 1 1 3L4X ALA A 869 ? UNP O43451 ? ? 'EXPRESSION TAG' 869 2 1 3L4X HIS A 870 ? UNP O43451 ? ? 'EXPRESSION TAG' 870 3 1 3L4X HIS A 871 ? UNP O43451 ? ? 'EXPRESSION TAG' 871 4 1 3L4X HIS A 872 ? UNP O43451 ? ? 'EXPRESSION TAG' 872 5 1 3L4X HIS A 873 ? UNP O43451 ? ? 'EXPRESSION TAG' 873 6 1 3L4X HIS A 874 ? UNP O43451 ? ? 'EXPRESSION TAG' 874 7 1 3L4X HIS A 875 ? UNP O43451 ? ? 'EXPRESSION TAG' 875 8 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NR3 non-polymer . ;(1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; ? 'C12 H24 O12 S2' 424.442 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3L4X _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.63 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 53.17 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.pdbx_details '20% PEG 3350, 0.2M sodium sulfate, pH 6.5, vapor diffusion, hanging drop, temperature 293K' _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2007-04-20 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9175 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_wavelength_list 0.9175 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 # _reflns.entry_id 3L4X _reflns.d_resolution_high 1.900 _reflns.d_resolution_low 30.000 _reflns.number_obs 82586 _reflns.pdbx_Rmerge_I_obs 0.112 _reflns.pdbx_netI_over_sigmaI 15.800 _reflns.pdbx_chi_squared 1.409 _reflns.pdbx_redundancy 7.900 _reflns.percent_possible_obs 99.600 _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.number_all ? _reflns.pdbx_Rsym_value ? _reflns.B_iso_Wilson_estimate ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # loop_ _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.number_measured_obs _reflns_shell.number_measured_all _reflns_shell.number_unique_obs _reflns_shell.Rmerge_I_obs _reflns_shell.meanI_over_sigI_obs _reflns_shell.pdbx_Rsym_value _reflns_shell.pdbx_chi_squared _reflns_shell.pdbx_redundancy _reflns_shell.percent_possible_obs _reflns_shell.number_unique_all _reflns_shell.percent_possible_all _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_ordinal 1.90 1.97 ? ? ? 0.354 ? ? 2.181 8.10 ? 8206 100.00 ? 1 1.97 2.05 ? ? ? 0.268 ? ? 1.889 8.10 ? 8183 100.00 ? 2 2.05 2.14 ? ? ? 0.220 ? ? 1.610 8.10 ? 8226 100.00 ? 3 2.14 2.25 ? ? ? 0.182 ? ? 1.503 8.10 ? 8195 100.00 ? 4 2.25 2.39 ? ? ? 0.157 ? ? 1.270 8.10 ? 8240 100.00 ? 5 2.39 2.58 ? ? ? 0.137 ? ? 1.220 8.10 ? 8251 100.00 ? 6 2.58 2.84 ? ? ? 0.120 ? ? 1.187 8.10 ? 8264 100.00 ? 7 2.84 3.25 ? ? ? 0.103 ? ? 1.186 8.00 ? 8307 99.90 ? 8 3.25 4.09 ? ? ? 0.089 ? ? 0.978 7.80 ? 8296 99.00 ? 9 4.09 30.00 ? ? ? 0.090 ? ? 0.988 6.80 ? 8418 96.70 ? 10 # _refine.entry_id 3L4X _refine.ls_d_res_high 1.900 _refine.ls_d_res_low 18.880 _refine.pdbx_ls_sigma_F 0.00 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 97.240 _refine.ls_number_reflns_obs 80580 _refine.ls_number_reflns_all ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.207 _refine.ls_R_factor_R_work 0.205 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free 0.244 _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free 5.000 _refine.ls_number_reflns_R_free 4032 _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 21.815 _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.pdbx_isotropic_thermal_model ? _refine.aniso_B[1][1] 0.010 _refine.aniso_B[2][2] 0.000 _refine.aniso_B[3][3] 0.000 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc 0.919 _refine.correlation_coeff_Fo_to_Fc_free 0.892 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_overall_ESU_R 0.163 _refine.pdbx_overall_ESU_R_Free 0.151 _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.200 _refine.pdbx_solvent_ion_probe_radii 0.800 _refine.pdbx_solvent_shrinkage_radii 0.800 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set ? _refine.B_iso_max 63.06 _refine.B_iso_min 6.65 _refine.occupancy_max 1.00 _refine.occupancy_min 0.50 _refine.pdbx_ls_sigma_I ? _refine.ls_redundancy_reflns_obs ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.overall_FOM_free_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6936 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 92 _refine_hist.number_atoms_solvent 613 _refine_hist.number_atoms_total 7641 _refine_hist.d_res_high 1.900 _refine_hist.d_res_low 18.880 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 7232 0.016 0.022 ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 9869 1.633 1.946 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 869 6.709 5.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 365 35.528 24.247 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 1101 12.833 15.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 40 17.337 15.000 ? 'X-RAY DIFFRACTION' ? r_chiral_restr 1063 0.120 0.200 ? 'X-RAY DIFFRACTION' ? r_gen_planes_refined 5641 0.007 0.020 ? 'X-RAY DIFFRACTION' ? r_nbd_refined 3516 0.208 0.200 ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 4916 0.315 0.200 ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 658 0.149 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 69 0.179 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 11 0.129 0.200 ? 'X-RAY DIFFRACTION' ? r_mcbond_it 4316 0.969 1.500 ? 'X-RAY DIFFRACTION' ? r_mcangle_it 7001 1.669 2.000 ? 'X-RAY DIFFRACTION' ? r_scbond_it 2916 2.592 3.000 ? 'X-RAY DIFFRACTION' ? r_scangle_it 2864 3.870 4.500 ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 1.900 _refine_ls_shell.d_res_low 1.949 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 94.960 _refine_ls_shell.number_reflns_R_work 5406 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.238 _refine_ls_shell.R_factor_R_free 0.345 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 304 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.number_reflns_all 5710 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3L4X _struct.title 'Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8' _struct.pdbx_descriptor 'Maltase-glucoamylase, intestinal (E.C.3.2.1.20, 3.2.1.3)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3L4X _struct_keywords.text ;Glycoside Hydrolase Family 31, Cell membrane, Disulfide bond, Glycoprotein, Glycosidase, Hydrolase, Membrane, Multifunctional enzyme, Polymorphism, Signal-anchor, Sulfation, Transmembrane ; _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 3 ? F N N 4 ? G N N 4 ? H N N 4 ? I N N 4 ? J N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 8 ? ARG A 12 ? ASN A 8 ARG A 12 5 ? 5 HELX_P HELX_P2 2 THR A 22 ? GLY A 30 ? THR A 22 GLY A 30 1 ? 9 HELX_P HELX_P3 3 SER A 155 ? GLY A 157 ? SER A 155 GLY A 157 5 ? 3 HELX_P HELX_P4 4 THR A 269 ? GLY A 282 ? THR A 269 GLY A 282 1 ? 14 HELX_P HELX_P5 5 SER A 288 ? LEU A 292 ? SER A 288 LEU A 292 5 ? 5 HELX_P HELX_P6 6 THR A 303 ? ALA A 317 ? THR A 303 ALA A 317 1 ? 15 HELX_P HELX_P7 7 ASP A 327 ? MET A 331 ? ASP A 327 MET A 331 5 ? 5 HELX_P HELX_P8 8 GLY A 346 ? ASN A 357 ? GLY A 346 ASN A 357 1 ? 12 HELX_P HELX_P9 9 TYR A 379 ? LYS A 389 ? TYR A 379 LYS A 389 1 ? 11 HELX_P HELX_P10 10 ASN A 417 ? ASN A 433 ? ASN A 417 ASN A 433 1 ? 17 HELX_P HELX_P11 11 ILE A 472 ? TYR A 476 ? ILE A 472 TYR A 476 5 ? 5 HELX_P HELX_P12 12 GLN A 493 ? HIS A 497 ? GLN A 493 HIS A 497 1 ? 5 HELX_P HELX_P13 13 LEU A 499 ? PHE A 516 ? LEU A 499 PHE A 516 1 ? 18 HELX_P HELX_P14 14 GLY A 531 ? PHE A 535 ? GLY A 531 PHE A 535 5 ? 5 HELX_P HELX_P15 15 THR A 546 ? PHE A 563 ? THR A 546 PHE A 563 1 ? 18 HELX_P HELX_P16 16 PRO A 580 ? ALA A 592 ? PRO A 580 ALA A 592 1 ? 13 HELX_P HELX_P17 17 ASP A 609 ? GLY A 614 ? ASP A 609 GLY A 614 5 ? 6 HELX_P HELX_P18 18 SER A 617 ? LEU A 633 ? SER A 617 LEU A 633 1 ? 17 HELX_P HELX_P19 19 LEU A 633 ? ARG A 647 ? LEU A 633 ARG A 647 1 ? 15 HELX_P HELX_P20 20 PRO A 654 ? TYR A 660 ? PRO A 654 TYR A 660 1 ? 7 HELX_P HELX_P21 21 ASP A 662 ? TRP A 666 ? ASP A 662 TRP A 666 5 ? 5 HELX_P HELX_P22 22 THR A 743 ? ARG A 748 ? THR A 743 ARG A 748 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 31 SG ? ? A CYS 15 A CYS 31 1_555 ? ? ? ? ? ? ? 2.031 ? disulf2 disulf ? ? A CYS 26 SG ? ? ? 1_555 A CYS 44 SG ? ? A CYS 26 A CYS 44 1_555 ? ? ? ? ? ? ? 2.952 ? disulf3 disulf ? ? A CYS 573 SG ? ? ? 1_555 A CYS 584 SG ? ? A CYS 573 A CYS 584 1_555 ? ? ? ? ? ? ? 2.078 ? covale1 covale ? ? A ASN 393 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 393 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.441 ? covale2 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 2001 A NAG 2002 1_555 ? ? ? ? ? ? ? 1.442 ? covale3 covale ? ? A ASN 741 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 741 A NAG 2003 1_555 ? ? ? ? ? ? ? 1.477 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLN 136 A . ? GLN 136 A PRO 137 A ? PRO 137 A 1 4.84 2 GLY 181 A . ? GLY 181 A GLU 182 A ? GLU 182 A 1 -2.58 3 ALA 248 A . ? ALA 248 A PRO 249 A ? PRO 249 A 1 -1.15 4 GLU 446 A . ? GLU 446 A VAL 447 A ? VAL 447 A 1 4.55 5 PRO 835 A . ? PRO 835 A SER 836 A ? SER 836 A 1 17.68 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 8 ? C ? 3 ? D ? 5 ? E ? 9 ? F ? 3 ? G ? 2 ? H ? 5 ? I ? 2 ? J ? 11 ? K ? 10 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? parallel E 5 6 ? parallel E 6 7 ? parallel E 7 8 ? parallel E 8 9 ? parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? parallel J 7 8 ? anti-parallel J 8 9 ? parallel J 9 10 ? anti-parallel J 10 11 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel K 5 6 ? anti-parallel K 6 7 ? parallel K 7 8 ? anti-parallel K 8 9 ? parallel K 9 10 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 CYS A 32 ? TRP A 33 ? CYS A 32 TRP A 33 A 2 CYS A 44 ? TYR A 45 ? CYS A 44 TYR A 45 B 1 TYR A 52 ? ASN A 60 ? TYR A 52 ASN A 60 B 2 GLY A 64 ? ASN A 71 ? GLY A 64 ASN A 71 B 3 ASN A 84 ? THR A 93 ? ASN A 84 THR A 93 B 4 ARG A 96 ? ASP A 103 ? ARG A 96 ASP A 103 B 5 LEU A 260 ? GLY A 267 ? LEU A 260 GLY A 267 B 6 SER A 230 ? LEU A 235 ? SER A 230 LEU A 235 B 7 GLN A 217 ? LEU A 223 ? GLN A 217 LEU A 223 B 8 VAL A 177 ? GLY A 181 ? VAL A 177 GLY A 181 C 1 TYR A 129 ? SER A 134 ? TYR A 129 SER A 134 C 2 SER A 139 ? ARG A 144 ? SER A 139 ARG A 144 C 3 VAL A 150 ? ASP A 153 ? VAL A 150 ASP A 153 D 1 LEU A 160 ? ALA A 162 ? LEU A 160 ALA A 162 D 2 PHE A 165 ? ARG A 171 ? PHE A 165 ARG A 171 D 3 ALA A 250 ? THR A 255 ? ALA A 250 THR A 255 D 4 MET A 241 ? GLN A 246 ? MET A 241 GLN A 246 D 5 LYS A 195 ? ILE A 199 ? LYS A 195 ILE A 199 E 1 VAL A 568 ? GLY A 569 ? VAL A 568 GLY A 569 E 2 ALA A 537 ? TRP A 539 ? ALA A 537 TRP A 539 E 3 ILE A 523 ? THR A 525 ? ILE A 523 THR A 525 E 4 GLY A 439 ? ILE A 442 ? GLY A 439 ILE A 442 E 5 LYS A 360 ? VAL A 365 ? LYS A 360 VAL A 365 E 6 VAL A 323 ? ALA A 326 ? VAL A 323 ALA A 326 E 7 PHE A 294 ? LEU A 296 ? PHE A 294 LEU A 296 E 8 SER A 597 ? ASN A 599 ? SER A 597 ASN A 599 E 9 ASP A 571 ? ILE A 572 ? ASP A 571 ILE A 572 F 1 ILE A 369 ? SER A 370 ? ILE A 369 SER A 370 F 2 GLY A 408 ? VAL A 411 ? GLY A 408 VAL A 411 F 3 GLY A 403 ? VAL A 405 ? GLY A 403 VAL A 405 G 1 VAL A 487 ? GLN A 488 ? VAL A 487 GLN A 488 G 2 GLY A 491 ? LYS A 492 ? GLY A 491 LYS A 492 H 1 ALA A 652 ? ARG A 653 ? ALA A 652 ARG A 653 H 2 PHE A 672 ? TRP A 674 ? PHE A 672 TRP A 674 H 3 LEU A 678 ? THR A 681 ? LEU A 678 THR A 681 H 4 GLY A 726 ? ARG A 730 ? GLY A 726 ARG A 730 H 5 TRP A 700 ? ASP A 702 ? TRP A 700 ASP A 702 I 1 LYS A 690 ? VAL A 695 ? LYS A 690 VAL A 695 I 2 GLN A 714 ? GLU A 719 ? GLN A 714 GLU A 719 J 1 VAL A 834 ? PRO A 835 ? VAL A 834 PRO A 835 J 2 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 J 3 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 J 4 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 J 5 LEU A 785 ? VAL A 791 ? LEU A 785 VAL A 791 J 6 ALA A 764 ? TRP A 770 ? ALA A 764 TRP A 770 J 7 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 J 8 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 J 9 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 J 10 VAL A 850 ? THR A 854 ? VAL A 850 THR A 854 J 11 THR A 841 ? ASP A 845 ? THR A 841 ASP A 845 K 1 VAL A 834 ? PRO A 835 ? VAL A 834 PRO A 835 K 2 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 K 3 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 K 4 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 K 5 LEU A 785 ? VAL A 791 ? LEU A 785 VAL A 791 K 6 ALA A 764 ? TRP A 770 ? ALA A 764 TRP A 770 K 7 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 K 8 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 K 9 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 K 10 LEU A 858 ? LEU A 859 ? LEU A 858 LEU A 859 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N CYS A 32 ? N CYS A 32 O TYR A 45 ? O TYR A 45 B 1 2 N HIS A 53 ? N HIS A 53 O LYS A 70 ? O LYS A 70 B 2 3 N LEU A 69 ? N LEU A 69 O VAL A 85 ? O VAL A 85 B 3 4 N GLU A 90 ? N GLU A 90 O HIS A 98 ? O HIS A 98 B 4 5 N PHE A 99 ? N PHE A 99 O PHE A 262 ? O PHE A 262 B 5 6 O TYR A 263 ? O TYR A 263 N PHE A 234 ? N PHE A 234 B 6 7 O PHE A 231 ? O PHE A 231 N CYS A 222 ? N CYS A 222 B 7 8 O LEU A 221 ? O LEU A 221 N TYR A 178 ? N TYR A 178 C 1 2 N GLN A 130 ? N GLN A 130 O THR A 143 ? O THR A 143 C 2 3 N VAL A 142 ? N VAL A 142 O PHE A 152 ? O PHE A 152 D 1 2 N ALA A 162 ? N ALA A 162 O PHE A 165 ? O PHE A 165 D 2 3 N LEU A 166 ? N LEU A 166 O THR A 255 ? O THR A 255 D 3 4 O THR A 252 ? O THR A 252 N VAL A 244 ? N VAL A 244 D 4 5 O LEU A 245 ? O LEU A 245 N LYS A 195 ? N LYS A 195 E 1 2 O GLY A 569 ? O GLY A 569 N HIS A 538 ? N HIS A 538 E 2 3 O ALA A 537 ? O ALA A 537 N ILE A 523 ? N ILE A 523 E 3 4 O LEU A 524 ? O LEU A 524 N ILE A 442 ? N ILE A 442 E 4 5 O TRP A 441 ? O TRP A 441 N ILE A 363 ? N ILE A 363 E 5 6 O LYS A 360 ? O LYS A 360 N GLN A 324 ? N GLN A 324 E 6 7 O HIS A 325 ? O HIS A 325 N LEU A 296 ? N LEU A 296 E 7 8 N HIS A 295 ? N HIS A 295 O SER A 597 ? O SER A 597 E 8 9 O ARG A 598 ? O ARG A 598 N ILE A 572 ? N ILE A 572 F 1 2 N ILE A 369 ? N ILE A 369 O VAL A 411 ? O VAL A 411 F 2 3 O THR A 410 ? O THR A 410 N GLY A 403 ? N GLY A 403 G 1 2 N GLN A 488 ? N GLN A 488 O GLY A 491 ? O GLY A 491 H 1 2 N ARG A 653 ? N ARG A 653 O LEU A 673 ? O LEU A 673 H 2 3 N PHE A 672 ? N PHE A 672 O ILE A 680 ? O ILE A 680 H 3 4 N LEU A 679 ? N LEU A 679 O HIS A 728 ? O HIS A 728 H 4 5 O LEU A 729 ? O LEU A 729 N TYR A 701 ? N TYR A 701 I 1 2 N VAL A 691 ? N VAL A 691 O MET A 718 ? O MET A 718 J 1 2 O VAL A 834 ? O VAL A 834 N HIS A 831 ? N HIS A 831 J 2 3 N SER A 825 ? N SER A 825 O ALA A 869 ? O ALA A 869 J 3 4 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 J 4 5 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 J 5 6 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 J 6 7 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 J 7 8 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 J 8 9 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 J 9 10 N ILE A 816 ? N ILE A 816 O ILE A 853 ? O ILE A 853 J 10 11 O THR A 854 ? O THR A 854 N THR A 841 ? N THR A 841 K 1 2 O VAL A 834 ? O VAL A 834 N HIS A 831 ? N HIS A 831 K 2 3 N SER A 825 ? N SER A 825 O ALA A 869 ? O ALA A 869 K 3 4 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 K 4 5 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 K 5 6 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 K 6 7 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 K 7 8 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 K 8 9 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 K 9 10 N PHE A 813 ? N PHE A 813 O LEU A 858 ? O LEU A 858 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 15 'BINDING SITE FOR RESIDUE NR3 A 1001' AC2 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE NAG A 2001' AC3 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 2002' AC4 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 2003' AC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL A 3001' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3002' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3003' AC8 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL A 3004' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 15 ASP A 203 ? ASP A 203 . ? 1_555 ? 2 AC1 15 TYR A 299 ? TYR A 299 . ? 1_555 ? 3 AC1 15 ASP A 327 ? ASP A 327 . ? 1_555 ? 4 AC1 15 ILE A 364 ? ILE A 364 . ? 1_555 ? 5 AC1 15 TRP A 441 ? TRP A 441 . ? 1_555 ? 6 AC1 15 ASP A 443 ? ASP A 443 . ? 1_555 ? 7 AC1 15 ARG A 526 ? ARG A 526 . ? 1_555 ? 8 AC1 15 TRP A 539 ? TRP A 539 . ? 1_555 ? 9 AC1 15 ASP A 542 ? ASP A 542 . ? 1_555 ? 10 AC1 15 PHE A 575 ? PHE A 575 . ? 1_555 ? 11 AC1 15 HIS A 600 ? HIS A 600 . ? 1_555 ? 12 AC1 15 HOH J . ? HOH A 4079 . ? 1_555 ? 13 AC1 15 HOH J . ? HOH A 4104 . ? 1_555 ? 14 AC1 15 HOH J . ? HOH A 4147 . ? 1_555 ? 15 AC1 15 HOH J . ? HOH A 4158 . ? 1_555 ? 16 AC2 11 LYS A 389 ? LYS A 389 . ? 1_555 ? 17 AC2 11 ASN A 393 ? ASN A 393 . ? 1_555 ? 18 AC2 11 GLY A 397 ? GLY A 397 . ? 1_555 ? 19 AC2 11 VAL A 398 ? VAL A 398 . ? 1_555 ? 20 AC2 11 VAL A 487 ? VAL A 487 . ? 1_555 ? 21 AC2 11 GLN A 488 ? GLN A 488 . ? 1_555 ? 22 AC2 11 HIS A 489 ? HIS A 489 . ? 1_555 ? 23 AC2 11 NAG D . ? NAG A 2002 . ? 1_555 ? 24 AC2 11 HOH J . ? HOH A 4182 . ? 1_555 ? 25 AC2 11 HOH J . ? HOH A 4263 . ? 1_555 ? 26 AC2 11 HOH J . ? HOH A 4594 . ? 1_555 ? 27 AC3 2 LYS A 389 ? LYS A 389 . ? 1_555 ? 28 AC3 2 NAG C . ? NAG A 2001 . ? 1_555 ? 29 AC4 10 SER A 146 ? SER A 146 . ? 2_454 ? 30 AC4 10 ASN A 147 ? ASN A 147 . ? 2_454 ? 31 AC4 10 ASN A 741 ? ASN A 741 . ? 1_555 ? 32 AC4 10 ALA A 746 ? ALA A 746 . ? 1_555 ? 33 AC4 10 ASN A 750 ? ASN A 750 . ? 1_555 ? 34 AC4 10 HOH J . ? HOH A 4160 . ? 1_555 ? 35 AC4 10 HOH J . ? HOH A 4455 . ? 2_454 ? 36 AC4 10 HOH J . ? HOH A 4503 . ? 1_555 ? 37 AC4 10 HOH J . ? HOH A 4558 . ? 1_555 ? 38 AC4 10 HOH J . ? HOH A 4639 . ? 1_555 ? 39 AC5 7 ALA A 285 ? ALA A 285 . ? 1_555 ? 40 AC5 7 ALA A 536 ? ALA A 536 . ? 1_555 ? 41 AC5 7 ALA A 537 ? ALA A 537 . ? 1_555 ? 42 AC5 7 MET A 567 ? MET A 567 . ? 1_555 ? 43 AC5 7 HOH J . ? HOH A 4109 . ? 1_555 ? 44 AC5 7 HOH J . ? HOH A 4154 . ? 1_555 ? 45 AC5 7 HOH J . ? HOH A 4290 . ? 1_555 ? 46 AC6 5 GLU A 582 ? GLU A 582 . ? 1_555 ? 47 AC6 5 ARG A 585 ? ARG A 585 . ? 1_555 ? 48 AC6 5 GLU A 689 ? GLU A 689 . ? 1_555 ? 49 AC6 5 GLY A 722 ? GLY A 722 . ? 1_555 ? 50 AC6 5 HOH J . ? HOH A 4152 . ? 1_555 ? 51 AC7 5 ASN A 306 ? ASN A 306 . ? 1_555 ? 52 AC7 5 GLU A 309 ? GLU A 309 . ? 1_555 ? 53 AC7 5 ARG A 313 ? ARG A 313 . ? 1_555 ? 54 AC7 5 ASP A 607 ? ASP A 607 . ? 1_555 ? 55 AC7 5 HOH J . ? HOH A 4033 . ? 1_555 ? 56 AC8 7 PHE A 65 ? PHE A 65 . ? 2_454 ? 57 AC8 7 VAL A 131 ? VAL A 131 . ? 2_454 ? 58 AC8 7 GLU A 132 ? GLU A 132 . ? 2_454 ? 59 AC8 7 ILE A 133 ? ILE A 133 . ? 2_454 ? 60 AC8 7 THR A 843 ? THR A 843 . ? 1_555 ? 61 AC8 7 THR A 854 ? THR A 854 . ? 1_555 ? 62 AC8 7 HOH J . ? HOH A 4582 . ? 1_555 ? # _atom_sites.entry_id 3L4X _atom_sites.fract_transf_matrix[1][1] 0.011471 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009138 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.009147 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 7 ? -13.053 -37.131 63.348 1.00 40.46 ? 7 VAL A N 1 ATOM 2 C CA . VAL A 1 7 ? -12.633 -36.218 62.247 1.00 40.16 ? 7 VAL A CA 1 ATOM 3 C C . VAL A 1 7 ? -13.456 -36.524 60.985 1.00 38.82 ? 7 VAL A C 1 ATOM 4 O O . VAL A 1 7 ? -13.037 -37.350 60.162 1.00 40.08 ? 7 VAL A O 1 ATOM 5 C CB . VAL A 1 7 ? -11.088 -36.335 61.937 1.00 40.48 ? 7 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 7 ? -10.624 -35.232 60.990 1.00 40.62 ? 7 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 7 ? -10.265 -36.297 63.221 1.00 42.31 ? 7 VAL A CG2 1 ATOM 8 N N . ASN A 1 8 ? -14.633 -35.887 60.885 1.00 36.86 ? 8 ASN A N 1 ATOM 9 C CA . ASN A 1 8 ? -15.442 -35.739 59.659 1.00 33.71 ? 8 ASN A CA 1 ATOM 10 C C . ASN A 1 8 ? -14.529 -35.839 58.460 1.00 31.59 ? 8 ASN A C 1 ATOM 11 O O . ASN A 1 8 ? -13.522 -35.135 58.392 1.00 30.18 ? 8 ASN A O 1 ATOM 12 C CB . ASN A 1 8 ? -16.108 -34.360 59.674 1.00 33.97 ? 8 ASN A CB 1 ATOM 13 C CG . ASN A 1 8 ? -17.100 -34.119 58.493 1.00 35.69 ? 8 ASN A CG 1 ATOM 14 O OD1 . ASN A 1 8 ? -16.948 -34.616 57.367 1.00 33.79 ? 8 ASN A OD1 1 ATOM 15 N ND2 . ASN A 1 8 ? -18.111 -33.303 58.770 1.00 40.61 ? 8 ASN A ND2 1 ATOM 16 N N . GLU A 1 9 ? -14.854 -36.713 57.517 1.00 29.69 ? 9 GLU A N 1 ATOM 17 C CA . GLU A 1 9 ? -13.905 -36.949 56.439 1.00 29.08 ? 9 GLU A CA 1 ATOM 18 C C . GLU A 1 9 ? -13.701 -35.739 55.512 1.00 26.32 ? 9 GLU A C 1 ATOM 19 O O . GLU A 1 9 ? -12.643 -35.597 54.922 1.00 24.61 ? 9 GLU A O 1 ATOM 20 C CB . GLU A 1 9 ? -14.172 -38.261 55.695 1.00 30.40 ? 9 GLU A CB 1 ATOM 21 C CG . GLU A 1 9 ? -15.485 -38.411 54.978 1.00 31.92 ? 9 GLU A CG 1 ATOM 22 C CD . GLU A 1 9 ? -15.610 -39.812 54.387 1.00 33.47 ? 9 GLU A CD 1 ATOM 23 O OE1 . GLU A 1 9 ? -15.472 -40.820 55.134 1.00 39.59 ? 9 GLU A OE1 1 ATOM 24 O OE2 . GLU A 1 9 ? -15.832 -39.917 53.159 1.00 40.17 ? 9 GLU A OE2 1 ATOM 25 N N . LEU A 1 10 ? -14.689 -34.841 55.427 1.00 23.03 ? 10 LEU A N 1 ATOM 26 C CA . LEU A 1 10 ? -14.532 -33.661 54.580 1.00 22.09 ? 10 LEU A CA 1 ATOM 27 C C . LEU A 1 10 ? -13.541 -32.657 55.129 1.00 20.02 ? 10 LEU A C 1 ATOM 28 O O . LEU A 1 10 ? -13.097 -31.796 54.395 1.00 19.94 ? 10 LEU A O 1 ATOM 29 C CB . LEU A 1 10 ? -15.872 -32.967 54.342 1.00 21.81 ? 10 LEU A CB 1 ATOM 30 C CG . LEU A 1 10 ? -17.014 -33.815 53.786 1.00 23.28 ? 10 LEU A CG 1 ATOM 31 C CD1 . LEU A 1 10 ? -18.155 -32.872 53.500 1.00 24.30 ? 10 LEU A CD1 1 ATOM 32 C CD2 . LEU A 1 10 ? -16.608 -34.537 52.522 1.00 23.67 ? 10 LEU A CD2 1 ATOM 33 N N . GLU A 1 11 ? -13.189 -32.783 56.408 1.00 18.84 ? 11 GLU A N 1 ATOM 34 C CA . GLU A 1 11 ? -12.271 -31.856 57.075 1.00 19.70 ? 11 GLU A CA 1 ATOM 35 C C . GLU A 1 11 ? -10.836 -32.396 57.163 1.00 18.47 ? 11 GLU A C 1 ATOM 36 O O . GLU A 1 11 ? -9.953 -31.711 57.672 1.00 17.19 ? 11 GLU A O 1 ATOM 37 C CB . GLU A 1 11 ? -12.781 -31.523 58.472 1.00 19.67 ? 11 GLU A CB 1 ATOM 38 C CG . GLU A 1 11 ? -14.091 -30.722 58.408 1.00 22.53 ? 11 GLU A CG 1 ATOM 39 C CD . GLU A 1 11 ? -14.756 -30.472 59.751 1.00 25.75 ? 11 GLU A CD 1 ATOM 40 O OE1 . GLU A 1 11 ? -14.111 -30.634 60.810 1.00 33.28 ? 11 GLU A OE1 1 ATOM 41 O OE2 . GLU A 1 11 ? -15.960 -30.080 59.729 1.00 33.47 ? 11 GLU A OE2 1 ATOM 42 N N . ARG A 1 12 ? -10.607 -33.600 56.655 1.00 18.40 ? 12 ARG A N 1 ATOM 43 C CA . ARG A 1 12 ? -9.228 -34.137 56.700 1.00 19.18 ? 12 ARG A CA 1 ATOM 44 C C . ARG A 1 12 ? -8.305 -33.373 55.764 1.00 18.10 ? 12 ARG A C 1 ATOM 45 O O . ARG A 1 12 ? -8.651 -33.141 54.606 1.00 19.16 ? 12 ARG A O 1 ATOM 46 C CB . ARG A 1 12 ? -9.203 -35.601 56.297 1.00 19.39 ? 12 ARG A CB 1 ATOM 47 C CG . ARG A 1 12 ? -10.083 -36.502 57.147 1.00 22.41 ? 12 ARG A CG 1 ATOM 48 C CD . ARG A 1 12 ? -10.170 -37.783 56.369 1.00 25.39 ? 12 ARG A CD 1 ATOM 49 N NE . ARG A 1 12 ? -10.860 -38.851 57.052 1.00 31.73 ? 12 ARG A NE 1 ATOM 50 C CZ . ARG A 1 12 ? -10.736 -40.143 56.727 1.00 32.68 ? 12 ARG A CZ 1 ATOM 51 N NH1 . ARG A 1 12 ? -9.887 -40.579 55.756 1.00 29.36 ? 12 ARG A NH1 1 ATOM 52 N NH2 . ARG A 1 12 ? -11.449 -41.006 57.411 1.00 31.58 ? 12 ARG A NH2 1 ATOM 53 N N . ILE A 1 13 ? -7.122 -33.042 56.257 1.00 17.38 ? 13 ILE A N 1 ATOM 54 C CA . ILE A 1 13 ? -6.122 -32.290 55.517 1.00 16.11 ? 13 ILE A CA 1 ATOM 55 C C . ILE A 1 13 ? -5.023 -33.287 55.102 1.00 16.38 ? 13 ILE A C 1 ATOM 56 O O . ILE A 1 13 ? -4.404 -33.919 55.943 1.00 14.25 ? 13 ILE A O 1 ATOM 57 C CB . ILE A 1 13 ? -5.556 -31.122 56.340 1.00 16.06 ? 13 ILE A CB 1 ATOM 58 C CG1 . ILE A 1 13 ? -6.667 -30.113 56.711 1.00 15.75 ? 13 ILE A CG1 1 ATOM 59 C CG2 . ILE A 1 13 ? -4.471 -30.365 55.584 1.00 15.74 ? 13 ILE A CG2 1 ATOM 60 C CD1 . ILE A 1 13 ? -7.349 -29.445 55.522 1.00 17.24 ? 13 ILE A CD1 1 ATOM 61 N N . ASN A 1 14 ? -4.867 -33.435 53.796 1.00 16.12 ? 14 ASN A N 1 ATOM 62 C CA . ASN A 1 14 ? -3.999 -34.449 53.195 1.00 16.91 ? 14 ASN A CA 1 ATOM 63 C C . ASN A 1 14 ? -2.523 -34.316 53.633 1.00 16.30 ? 14 ASN A C 1 ATOM 64 O O . ASN A 1 14 ? -1.884 -33.279 53.405 1.00 16.56 ? 14 ASN A O 1 ATOM 65 C CB . ASN A 1 14 ? -4.135 -34.363 51.671 1.00 16.42 ? 14 ASN A CB 1 ATOM 66 C CG . ASN A 1 14 ? -3.379 -35.483 50.941 1.00 19.19 ? 14 ASN A CG 1 ATOM 67 O OD1 . ASN A 1 14 ? -2.937 -36.439 51.556 1.00 16.46 ? 14 ASN A OD1 1 ATOM 68 N ND2 . ASN A 1 14 ? -3.260 -35.361 49.617 1.00 19.02 ? 14 ASN A ND2 1 ATOM 69 N N . CYS A 1 15 ? -1.979 -35.395 54.221 1.00 17.56 ? 15 CYS A N 1 ATOM 70 C CA . CYS A 1 15 ? -0.600 -35.439 54.750 1.00 18.26 ? 15 CYS A CA 1 ATOM 71 C C . CYS A 1 15 ? 0.363 -36.076 53.731 1.00 18.14 ? 15 CYS A C 1 ATOM 72 O O . CYS A 1 15 ? 1.589 -36.102 53.947 1.00 17.81 ? 15 CYS A O 1 ATOM 73 C CB . CYS A 1 15 ? -0.597 -36.238 56.081 1.00 19.04 ? 15 CYS A CB 1 ATOM 74 S SG . CYS A 1 15 ? 1.031 -36.624 56.748 1.00 23.07 ? 15 CYS A SG 1 ATOM 75 N N . ILE A 1 16 ? -0.202 -36.613 52.640 1.00 17.21 ? 16 ILE A N 1 ATOM 76 C CA . ILE A 1 16 ? 0.611 -37.204 51.571 1.00 17.06 ? 16 ILE A CA 1 ATOM 77 C C . ILE A 1 16 ? 0.202 -36.595 50.231 1.00 17.57 ? 16 ILE A C 1 ATOM 78 O O . ILE A 1 16 ? -0.448 -37.264 49.423 1.00 18.64 ? 16 ILE A O 1 ATOM 79 C CB . ILE A 1 16 ? 0.518 -38.761 51.516 1.00 16.28 ? 16 ILE A CB 1 ATOM 80 C CG1 . ILE A 1 16 ? 0.809 -39.369 52.878 1.00 16.16 ? 16 ILE A CG1 1 ATOM 81 C CG2 . ILE A 1 16 ? 1.468 -39.286 50.475 1.00 18.60 ? 16 ILE A CG2 1 ATOM 82 C CD1 . ILE A 1 16 ? 0.724 -40.917 52.935 1.00 14.93 ? 16 ILE A CD1 1 ATOM 83 N N . PRO A 1 17 ? 0.588 -35.330 49.987 1.00 18.49 ? 17 PRO A N 1 ATOM 84 C CA . PRO A 1 17 ? 0.244 -34.678 48.723 1.00 20.56 ? 17 PRO A CA 1 ATOM 85 C C . PRO A 1 17 ? 1.130 -35.108 47.548 1.00 22.63 ? 17 PRO A C 1 ATOM 86 O O . PRO A 1 17 ? 0.818 -34.791 46.384 1.00 23.14 ? 17 PRO A O 1 ATOM 87 C CB . PRO A 1 17 ? 0.478 -33.199 49.047 1.00 20.28 ? 17 PRO A CB 1 ATOM 88 C CG . PRO A 1 17 ? 1.596 -33.197 50.004 1.00 20.23 ? 17 PRO A CG 1 ATOM 89 C CD . PRO A 1 17 ? 1.336 -34.416 50.873 1.00 19.16 ? 17 PRO A CD 1 ATOM 90 N N . ASP A 1 18 ? 2.204 -35.844 47.853 1.00 22.38 ? 18 ASP A N 1 ATOM 91 C CA . ASP A 1 18 ? 3.355 -35.976 46.965 1.00 24.48 ? 18 ASP A CA 1 ATOM 92 C C . ASP A 1 18 ? 3.474 -37.351 46.336 1.00 26.11 ? 18 ASP A C 1 ATOM 93 O O . ASP A 1 18 ? 4.323 -37.555 45.457 1.00 26.77 ? 18 ASP A O 1 ATOM 94 C CB . ASP A 1 18 ? 4.640 -35.708 47.747 1.00 23.77 ? 18 ASP A CB 1 ATOM 95 C CG . ASP A 1 18 ? 4.705 -36.488 49.085 1.00 25.55 ? 18 ASP A CG 1 ATOM 96 O OD1 . ASP A 1 18 ? 3.690 -36.557 49.830 1.00 25.01 ? 18 ASP A OD1 1 ATOM 97 O OD2 . ASP A 1 18 ? 5.799 -37.019 49.413 1.00 28.26 ? 18 ASP A OD2 1 ATOM 98 N N . GLN A 1 19 ? 2.670 -38.299 46.807 1.00 25.72 ? 19 GLN A N 1 ATOM 99 C CA . GLN A 1 19 ? 2.764 -39.667 46.310 1.00 27.53 ? 19 GLN A CA 1 ATOM 100 C C . GLN A 1 19 ? 1.490 -40.442 46.589 1.00 27.88 ? 19 GLN A C 1 ATOM 101 O O . GLN A 1 19 ? 0.632 -39.943 47.307 1.00 27.74 ? 19 GLN A O 1 ATOM 102 C CB . GLN A 1 19 ? 3.953 -40.360 46.953 1.00 27.81 ? 19 GLN A CB 1 ATOM 103 C CG . GLN A 1 19 ? 3.823 -40.620 48.409 1.00 28.35 ? 19 GLN A CG 1 ATOM 104 C CD . GLN A 1 19 ? 5.168 -40.885 49.048 1.00 32.90 ? 19 GLN A CD 1 ATOM 105 O OE1 . GLN A 1 19 ? 6.185 -40.386 48.590 1.00 36.84 ? 19 GLN A OE1 1 ATOM 106 N NE2 . GLN A 1 19 ? 5.179 -41.670 50.098 1.00 31.54 ? 19 GLN A NE2 1 ATOM 107 N N . PRO A 1 20 ? 1.348 -41.657 45.999 1.00 28.19 ? 20 PRO A N 1 ATOM 108 C CA . PRO A 1 20 ? 0.228 -42.541 46.345 1.00 27.81 ? 20 PRO A CA 1 ATOM 109 C C . PRO A 1 20 ? 0.260 -42.870 47.849 1.00 26.43 ? 20 PRO A C 1 ATOM 110 O O . PRO A 1 20 ? 1.296 -43.255 48.346 1.00 26.55 ? 20 PRO A O 1 ATOM 111 C CB . PRO A 1 20 ? 0.513 -43.806 45.528 1.00 27.55 ? 20 PRO A CB 1 ATOM 112 C CG . PRO A 1 20 ? 1.368 -43.327 44.386 1.00 28.51 ? 20 PRO A CG 1 ATOM 113 C CD . PRO A 1 20 ? 2.218 -42.256 44.964 1.00 28.91 ? 20 PRO A CD 1 ATOM 114 N N . PRO A 1 21 ? -0.866 -42.718 48.555 1.00 25.65 ? 21 PRO A N 1 ATOM 115 C CA . PRO A 1 21 ? -0.885 -42.871 50.025 1.00 25.06 ? 21 PRO A CA 1 ATOM 116 C C . PRO A 1 21 ? -0.631 -44.301 50.512 1.00 23.98 ? 21 PRO A C 1 ATOM 117 O O . PRO A 1 21 ? -1.279 -45.245 50.035 1.00 23.22 ? 21 PRO A O 1 ATOM 118 C CB . PRO A 1 21 ? -2.304 -42.442 50.415 1.00 24.76 ? 21 PRO A CB 1 ATOM 119 C CG . PRO A 1 21 ? -3.131 -42.674 49.172 1.00 27.08 ? 21 PRO A CG 1 ATOM 120 C CD . PRO A 1 21 ? -2.197 -42.394 48.006 1.00 26.64 ? 21 PRO A CD 1 ATOM 121 N N . THR A 1 22 ? 0.287 -44.442 51.470 1.00 22.47 ? 22 THR A N 1 ATOM 122 C CA . THR A 1 22 ? 0.593 -45.723 52.083 1.00 21.94 ? 22 THR A CA 1 ATOM 123 C C . THR A 1 22 ? 0.638 -45.574 53.603 1.00 22.29 ? 22 THR A C 1 ATOM 124 O O . THR A 1 22 ? 0.982 -44.505 54.103 1.00 21.47 ? 22 THR A O 1 ATOM 125 C CB . THR A 1 22 ? 1.949 -46.306 51.580 1.00 21.93 ? 22 THR A CB 1 ATOM 126 O OG1 . THR A 1 22 ? 3.034 -45.473 51.978 1.00 21.92 ? 22 THR A OG1 1 ATOM 127 C CG2 . THR A 1 22 ? 1.966 -46.430 50.042 1.00 20.77 ? 22 THR A CG2 1 ATOM 128 N N . LYS A 1 23 ? 0.296 -46.637 54.321 1.00 22.66 ? 23 LYS A N 1 ATOM 129 C CA . LYS A 1 23 ? 0.350 -46.610 55.795 1.00 23.49 ? 23 LYS A CA 1 ATOM 130 C C . LYS A 1 23 ? 1.784 -46.409 56.248 1.00 22.95 ? 23 LYS A C 1 ATOM 131 O O . LYS A 1 23 ? 2.031 -45.772 57.246 1.00 21.96 ? 23 LYS A O 1 ATOM 132 C CB . LYS A 1 23 ? -0.206 -47.894 56.408 1.00 24.40 ? 23 LYS A CB 1 ATOM 133 C CG . LYS A 1 23 ? -0.443 -47.795 57.950 1.00 25.38 ? 23 LYS A CG 1 ATOM 134 C CD . LYS A 1 23 ? -1.035 -49.102 58.483 1.00 26.97 ? 23 LYS A CD 1 ATOM 135 C CE . LYS A 1 23 ? -1.351 -49.050 59.996 1.00 30.14 ? 23 LYS A CE 1 ATOM 136 N NZ . LYS A 1 23 ? -0.405 -48.294 60.860 1.00 33.60 ? 23 LYS A NZ 1 ATOM 137 N N . ALA A 1 24 ? 2.740 -46.968 55.517 1.00 22.43 ? 24 ALA A N 1 ATOM 138 C CA . ALA A 1 24 ? 4.128 -46.840 55.904 1.00 22.75 ? 24 ALA A CA 1 ATOM 139 C C . ALA A 1 24 ? 4.552 -45.359 55.936 1.00 22.48 ? 24 ALA A C 1 ATOM 140 O O . ALA A 1 24 ? 5.131 -44.878 56.920 1.00 23.01 ? 24 ALA A O 1 ATOM 141 C CB . ALA A 1 24 ? 5.031 -47.675 54.935 1.00 23.93 ? 24 ALA A CB 1 ATOM 142 N N . THR A 1 25 ? 4.227 -44.622 54.878 1.00 21.53 ? 25 THR A N 1 ATOM 143 C CA . THR A 1 25 ? 4.590 -43.212 54.801 1.00 22.31 ? 25 THR A CA 1 ATOM 144 C C . THR A 1 25 ? 3.774 -42.448 55.842 1.00 21.73 ? 25 THR A C 1 ATOM 145 O O . THR A 1 25 ? 4.304 -41.576 56.516 1.00 20.87 ? 25 THR A O 1 ATOM 146 C CB . THR A 1 25 ? 4.356 -42.630 53.384 1.00 21.96 ? 25 THR A CB 1 ATOM 147 O OG1 . THR A 1 25 ? 5.360 -43.134 52.496 1.00 24.89 ? 25 THR A OG1 1 ATOM 148 C CG2 . THR A 1 25 ? 4.482 -41.078 53.373 1.00 21.14 ? 25 THR A CG2 1 ATOM 149 N N . CYS A 1 26 ? 2.500 -42.821 55.968 1.00 23.16 ? 26 CYS A N 1 ATOM 150 C CA . CYS A 1 26 ? 1.615 -42.196 56.945 1.00 23.82 ? 26 CYS A CA 1 ATOM 151 C C . CYS A 1 26 ? 2.197 -42.294 58.346 1.00 23.54 ? 26 CYS A C 1 ATOM 152 O O . CYS A 1 26 ? 2.290 -41.287 59.057 1.00 22.31 ? 26 CYS A O 1 ATOM 153 C CB . CYS A 1 26 ? 0.254 -42.861 56.920 1.00 24.32 ? 26 CYS A CB 1 ATOM 154 S SG . CYS A 1 26 ? -0.859 -41.997 58.050 1.00 28.90 ? 26 CYS A SG 1 ATOM 155 N N . ASP A 1 27 ? 2.609 -43.508 58.724 1.00 24.34 ? 27 ASP A N 1 ATOM 156 C CA . ASP A 1 27 ? 3.223 -43.761 60.045 1.00 25.14 ? 27 ASP A CA 1 ATOM 157 C C . ASP A 1 27 ? 4.509 -42.993 60.253 1.00 24.99 ? 27 ASP A C 1 ATOM 158 O O . ASP A 1 27 ? 4.723 -42.434 61.323 1.00 25.33 ? 27 ASP A O 1 ATOM 159 C CB . ASP A 1 27 ? 3.459 -45.263 60.255 1.00 24.99 ? 27 ASP A CB 1 ATOM 160 C CG . ASP A 1 27 ? 2.169 -46.022 60.477 1.00 28.70 ? 27 ASP A CG 1 ATOM 161 O OD1 . ASP A 1 27 ? 1.125 -45.387 60.708 1.00 29.98 ? 27 ASP A OD1 1 ATOM 162 O OD2 . ASP A 1 27 ? 2.171 -47.259 60.414 1.00 34.13 ? 27 ASP A OD2 1 ATOM 163 N N . GLN A 1 28 ? 5.378 -42.968 59.240 1.00 24.89 ? 28 GLN A N 1 ATOM 164 C CA . GLN A 1 28 ? 6.638 -42.212 59.306 1.00 25.46 ? 28 GLN A CA 1 ATOM 165 C C . GLN A 1 28 ? 6.433 -40.703 59.528 1.00 24.25 ? 28 GLN A C 1 ATOM 166 O O . GLN A 1 28 ? 7.258 -40.004 60.166 1.00 23.44 ? 28 GLN A O 1 ATOM 167 C CB . GLN A 1 28 ? 7.415 -42.448 58.004 1.00 25.47 ? 28 GLN A CB 1 ATOM 168 C CG . GLN A 1 28 ? 8.708 -41.683 57.881 1.00 28.11 ? 28 GLN A CG 1 ATOM 169 C CD . GLN A 1 28 ? 9.265 -41.672 56.462 1.00 30.63 ? 28 GLN A CD 1 ATOM 170 O OE1 . GLN A 1 28 ? 8.838 -42.472 55.588 1.00 39.31 ? 28 GLN A OE1 1 ATOM 171 N NE2 . GLN A 1 28 ? 10.197 -40.735 56.202 1.00 34.71 ? 28 GLN A NE2 1 ATOM 172 N N . ARG A 1 29 ? 5.335 -40.191 58.987 1.00 22.65 ? 29 ARG A N 1 ATOM 173 C CA . ARG A 1 29 ? 5.089 -38.745 59.011 1.00 22.00 ? 29 ARG A CA 1 ATOM 174 C C . ARG A 1 29 ? 4.298 -38.361 60.253 1.00 22.18 ? 29 ARG A C 1 ATOM 175 O O . ARG A 1 29 ? 4.085 -37.169 60.520 1.00 22.29 ? 29 ARG A O 1 ATOM 176 C CB . ARG A 1 29 ? 4.363 -38.322 57.730 1.00 21.51 ? 29 ARG A CB 1 ATOM 177 C CG . ARG A 1 29 ? 5.194 -38.502 56.494 1.00 22.13 ? 29 ARG A CG 1 ATOM 178 C CD . ARG A 1 29 ? 4.541 -37.894 55.271 1.00 24.27 ? 29 ARG A CD 1 ATOM 179 N NE . ARG A 1 29 ? 5.436 -38.107 54.136 1.00 22.75 ? 29 ARG A NE 1 ATOM 180 C CZ . ARG A 1 29 ? 5.182 -37.747 52.898 1.00 23.09 ? 29 ARG A CZ 1 ATOM 181 N NH1 . ARG A 1 29 ? 4.058 -37.098 52.598 1.00 16.61 ? 29 ARG A NH1 1 ATOM 182 N NH2 . ARG A 1 29 ? 6.079 -38.016 51.962 1.00 22.24 ? 29 ARG A NH2 1 ATOM 183 N N . GLY A 1 30 ? 3.875 -39.381 61.014 1.00 21.86 ? 30 GLY A N 1 ATOM 184 C CA . GLY A 1 30 ? 3.084 -39.218 62.227 1.00 20.99 ? 30 GLY A CA 1 ATOM 185 C C . GLY A 1 30 ? 1.663 -38.711 61.960 1.00 21.83 ? 30 GLY A C 1 ATOM 186 O O . GLY A 1 30 ? 1.109 -37.980 62.776 1.00 21.75 ? 30 GLY A O 1 ATOM 187 N N . CYS A 1 31 ? 1.073 -39.121 60.842 1.00 20.48 ? 31 CYS A N 1 ATOM 188 C CA . CYS A 1 31 ? -0.290 -38.699 60.457 1.00 21.41 ? 31 CYS A CA 1 ATOM 189 C C . CYS A 1 31 ? -1.307 -39.791 60.732 1.00 21.41 ? 31 CYS A C 1 ATOM 190 O O . CYS A 1 31 ? -0.948 -40.850 61.272 1.00 22.27 ? 31 CYS A O 1 ATOM 191 C CB . CYS A 1 31 ? -0.290 -38.241 58.985 1.00 20.55 ? 31 CYS A CB 1 ATOM 192 S SG . CYS A 1 31 ? 0.681 -36.739 58.745 1.00 22.00 ? 31 CYS A SG 1 ATOM 193 N N . CYS A 1 32 ? -2.584 -39.551 60.425 1.00 21.40 ? 32 CYS A N 1 ATOM 194 C CA . CYS A 1 32 ? -3.630 -40.529 60.702 1.00 23.32 ? 32 CYS A CA 1 ATOM 195 C C . CYS A 1 32 ? -3.979 -41.318 59.434 1.00 23.08 ? 32 CYS A C 1 ATOM 196 O O . CYS A 1 32 ? -4.048 -40.743 58.346 1.00 21.77 ? 32 CYS A O 1 ATOM 197 C CB . CYS A 1 32 ? -4.891 -39.836 61.206 1.00 23.59 ? 32 CYS A CB 1 ATOM 198 S SG . CYS A 1 32 ? -4.562 -38.654 62.488 1.00 27.13 ? 32 CYS A SG 1 ATOM 199 N N . TRP A 1 33 ? -4.206 -42.626 59.585 1.00 23.57 ? 33 TRP A N 1 ATOM 200 C CA . TRP A 1 33 ? -4.496 -43.518 58.463 1.00 24.93 ? 33 TRP A CA 1 ATOM 201 C C . TRP A 1 33 ? -5.933 -44.055 58.505 1.00 26.97 ? 33 TRP A C 1 ATOM 202 O O . TRP A 1 33 ? -6.355 -44.651 59.498 1.00 27.05 ? 33 TRP A O 1 ATOM 203 C CB . TRP A 1 33 ? -3.497 -44.688 58.472 1.00 24.96 ? 33 TRP A CB 1 ATOM 204 C CG . TRP A 1 33 ? -3.668 -45.649 57.360 1.00 23.73 ? 33 TRP A CG 1 ATOM 205 C CD1 . TRP A 1 33 ? -4.150 -46.932 57.452 1.00 25.20 ? 33 TRP A CD1 1 ATOM 206 C CD2 . TRP A 1 33 ? -3.340 -45.442 55.977 1.00 24.76 ? 33 TRP A CD2 1 ATOM 207 N NE1 . TRP A 1 33 ? -4.163 -47.521 56.204 1.00 23.54 ? 33 TRP A NE1 1 ATOM 208 C CE2 . TRP A 1 33 ? -3.665 -46.639 55.284 1.00 24.84 ? 33 TRP A CE2 1 ATOM 209 C CE3 . TRP A 1 33 ? -2.818 -44.363 55.251 1.00 23.53 ? 33 TRP A CE3 1 ATOM 210 C CZ2 . TRP A 1 33 ? -3.470 -46.788 53.907 1.00 24.16 ? 33 TRP A CZ2 1 ATOM 211 C CZ3 . TRP A 1 33 ? -2.621 -44.516 53.875 1.00 23.81 ? 33 TRP A CZ3 1 ATOM 212 C CH2 . TRP A 1 33 ? -2.960 -45.718 53.222 1.00 24.68 ? 33 TRP A CH2 1 ATOM 213 N N . ASN A 1 34 ? -6.685 -43.846 57.428 1.00 28.44 ? 34 ASN A N 1 ATOM 214 C CA . ASN A 1 34 ? -8.058 -44.339 57.336 1.00 31.36 ? 34 ASN A CA 1 ATOM 215 C C . ASN A 1 34 ? -8.444 -44.388 55.864 1.00 32.82 ? 34 ASN A C 1 ATOM 216 O O . ASN A 1 34 ? -8.931 -43.390 55.304 1.00 31.92 ? 34 ASN A O 1 ATOM 217 C CB . ASN A 1 34 ? -9.017 -43.454 58.151 1.00 31.89 ? 34 ASN A CB 1 ATOM 218 C CG . ASN A 1 34 ? -10.470 -43.978 58.169 1.00 34.87 ? 34 ASN A CG 1 ATOM 219 O OD1 . ASN A 1 34 ? -10.884 -44.768 57.325 1.00 38.59 ? 34 ASN A OD1 1 ATOM 220 N ND2 . ASN A 1 34 ? -11.245 -43.507 59.130 1.00 36.87 ? 34 ASN A ND2 1 ATOM 221 N N . PRO A 1 35 ? -8.204 -45.546 55.214 1.00 34.80 ? 35 PRO A N 1 ATOM 222 C CA . PRO A 1 35 ? -8.481 -45.654 53.795 1.00 36.48 ? 35 PRO A CA 1 ATOM 223 C C . PRO A 1 35 ? -9.962 -45.796 53.465 1.00 38.38 ? 35 PRO A C 1 ATOM 224 O O . PRO A 1 35 ? -10.290 -45.912 52.292 1.00 39.55 ? 35 PRO A O 1 ATOM 225 C CB . PRO A 1 35 ? -7.733 -46.929 53.369 1.00 36.13 ? 35 PRO A CB 1 ATOM 226 C CG . PRO A 1 35 ? -6.995 -47.400 54.581 1.00 36.05 ? 35 PRO A CG 1 ATOM 227 C CD . PRO A 1 35 ? -7.652 -46.798 55.758 1.00 34.71 ? 35 PRO A CD 1 ATOM 228 N N . GLN A 1 36 ? -10.843 -45.771 54.461 1.00 40.11 ? 36 GLN A N 1 ATOM 229 C CA . GLN A 1 36 ? -12.272 -46.093 54.230 1.00 42.49 ? 36 GLN A CA 1 ATOM 230 C C . GLN A 1 36 ? -13.208 -44.938 53.772 1.00 42.94 ? 36 GLN A C 1 ATOM 231 O O . GLN A 1 36 ? -14.431 -45.122 53.735 1.00 43.69 ? 36 GLN A O 1 ATOM 232 C CB . GLN A 1 36 ? -12.900 -46.825 55.443 1.00 42.94 ? 36 GLN A CB 1 ATOM 233 C CG . GLN A 1 36 ? -12.127 -48.034 56.021 1.00 45.83 ? 36 GLN A CG 1 ATOM 234 C CD . GLN A 1 36 ? -11.743 -49.090 54.985 1.00 49.16 ? 36 GLN A CD 1 ATOM 235 O OE1 . GLN A 1 36 ? -12.498 -49.378 54.039 1.00 49.52 ? 36 GLN A OE1 1 ATOM 236 N NE2 . GLN A 1 36 ? -10.562 -49.682 55.169 1.00 49.80 ? 36 GLN A NE2 1 ATOM 237 N N . GLY A 1 37 ? -12.660 -43.774 53.414 1.00 43.28 ? 37 GLY A N 1 ATOM 238 C CA . GLY A 1 37 ? -13.494 -42.641 52.950 1.00 42.80 ? 37 GLY A CA 1 ATOM 239 C C . GLY A 1 37 ? -13.987 -42.757 51.506 1.00 42.66 ? 37 GLY A C 1 ATOM 240 O O . GLY A 1 37 ? -13.650 -43.727 50.797 1.00 43.81 ? 37 GLY A O 1 ATOM 241 N N . ALA A 1 38 ? -14.774 -41.770 51.055 1.00 41.24 ? 38 ALA A N 1 ATOM 242 C CA . ALA A 1 38 ? -15.236 -41.715 49.658 1.00 39.52 ? 38 ALA A CA 1 ATOM 243 C C . ALA A 1 38 ? -14.105 -41.300 48.713 1.00 38.29 ? 38 ALA A C 1 ATOM 244 O O . ALA A 1 38 ? -13.018 -40.954 49.174 1.00 37.47 ? 38 ALA A O 1 ATOM 245 C CB . ALA A 1 38 ? -16.407 -40.763 49.533 1.00 39.99 ? 38 ALA A CB 1 ATOM 246 N N . VAL A 1 39 ? -14.355 -41.330 47.402 1.00 36.02 ? 39 VAL A N 1 ATOM 247 C CA . VAL A 1 39 ? -13.350 -40.889 46.424 1.00 34.04 ? 39 VAL A CA 1 ATOM 248 C C . VAL A 1 39 ? -12.729 -39.528 46.808 1.00 32.22 ? 39 VAL A C 1 ATOM 249 O O . VAL A 1 39 ? -13.426 -38.612 47.258 1.00 31.94 ? 39 VAL A O 1 ATOM 250 C CB . VAL A 1 39 ? -13.881 -40.891 44.950 1.00 33.99 ? 39 VAL A CB 1 ATOM 251 C CG1 . VAL A 1 39 ? -14.988 -39.862 44.744 1.00 34.99 ? 39 VAL A CG1 1 ATOM 252 C CG2 . VAL A 1 39 ? -12.737 -40.668 43.963 1.00 34.28 ? 39 VAL A CG2 1 ATOM 253 N N . SER A 1 40 ? -11.408 -39.447 46.684 1.00 29.86 ? 40 SER A N 1 ATOM 254 C CA . SER A 1 40 ? -10.638 -38.199 46.872 1.00 28.59 ? 40 SER A CA 1 ATOM 255 C C . SER A 1 40 ? -10.459 -37.803 48.331 1.00 26.18 ? 40 SER A C 1 ATOM 256 O O . SER A 1 40 ? -9.617 -36.970 48.635 1.00 26.05 ? 40 SER A O 1 ATOM 257 C CB . SER A 1 40 ? -11.211 -37.020 46.059 1.00 28.83 ? 40 SER A CB 1 ATOM 258 O OG . SER A 1 40 ? -11.376 -37.375 44.690 1.00 32.86 ? 40 SER A OG 1 ATOM 259 N N . VAL A 1 41 ? -11.211 -38.420 49.234 1.00 23.59 ? 41 VAL A N 1 ATOM 260 C CA . VAL A 1 41 ? -10.990 -38.196 50.668 1.00 22.72 ? 41 VAL A CA 1 ATOM 261 C C . VAL A 1 41 ? -9.602 -38.727 51.025 1.00 21.25 ? 41 VAL A C 1 ATOM 262 O O . VAL A 1 41 ? -9.299 -39.877 50.719 1.00 21.13 ? 41 VAL A O 1 ATOM 263 C CB . VAL A 1 41 ? -12.067 -38.860 51.522 1.00 22.79 ? 41 VAL A CB 1 ATOM 264 C CG1 . VAL A 1 41 ? -11.741 -38.769 53.031 1.00 23.20 ? 41 VAL A CG1 1 ATOM 265 C CG2 . VAL A 1 41 ? -13.399 -38.217 51.211 1.00 22.55 ? 41 VAL A CG2 1 ATOM 266 N N . PRO A 1 42 ? -8.762 -37.889 51.655 1.00 20.57 ? 42 PRO A N 1 ATOM 267 C CA . PRO A 1 42 ? -7.385 -38.330 51.915 1.00 20.27 ? 42 PRO A CA 1 ATOM 268 C C . PRO A 1 42 ? -7.344 -39.542 52.835 1.00 20.37 ? 42 PRO A C 1 ATOM 269 O O . PRO A 1 42 ? -7.917 -39.526 53.917 1.00 21.64 ? 42 PRO A O 1 ATOM 270 C CB . PRO A 1 42 ? -6.750 -37.123 52.646 1.00 20.16 ? 42 PRO A CB 1 ATOM 271 C CG . PRO A 1 42 ? -7.596 -35.975 52.350 1.00 21.90 ? 42 PRO A CG 1 ATOM 272 C CD . PRO A 1 42 ? -9.003 -36.529 52.167 1.00 19.82 ? 42 PRO A CD 1 ATOM 273 N N . TRP A 1 43 ? -6.635 -40.582 52.423 1.00 21.44 ? 43 TRP A N 1 ATOM 274 C CA . TRP A 1 43 ? -6.440 -41.754 53.279 1.00 21.53 ? 43 TRP A CA 1 ATOM 275 C C . TRP A 1 43 ? -5.496 -41.434 54.445 1.00 20.27 ? 43 TRP A C 1 ATOM 276 O O . TRP A 1 43 ? -5.625 -41.962 55.546 1.00 21.06 ? 43 TRP A O 1 ATOM 277 C CB . TRP A 1 43 ? -5.857 -42.874 52.414 1.00 22.95 ? 43 TRP A CB 1 ATOM 278 C CG . TRP A 1 43 ? -6.843 -43.509 51.490 1.00 25.00 ? 43 TRP A CG 1 ATOM 279 C CD1 . TRP A 1 43 ? -8.139 -43.104 51.243 1.00 26.30 ? 43 TRP A CD1 1 ATOM 280 C CD2 . TRP A 1 43 ? -6.618 -44.655 50.657 1.00 26.89 ? 43 TRP A CD2 1 ATOM 281 N NE1 . TRP A 1 43 ? -8.731 -43.948 50.342 1.00 26.51 ? 43 TRP A NE1 1 ATOM 282 C CE2 . TRP A 1 43 ? -7.828 -44.907 49.963 1.00 26.67 ? 43 TRP A CE2 1 ATOM 283 C CE3 . TRP A 1 43 ? -5.525 -45.515 50.458 1.00 27.01 ? 43 TRP A CE3 1 ATOM 284 C CZ2 . TRP A 1 43 ? -7.969 -45.958 49.053 1.00 26.44 ? 43 TRP A CZ2 1 ATOM 285 C CZ3 . TRP A 1 43 ? -5.660 -46.568 49.550 1.00 27.22 ? 43 TRP A CZ3 1 ATOM 286 C CH2 . TRP A 1 43 ? -6.895 -46.787 48.867 1.00 26.90 ? 43 TRP A CH2 1 ATOM 287 N N . CYS A 1 44 ? -4.538 -40.566 54.189 1.00 19.65 ? 44 CYS A N 1 ATOM 288 C CA . CYS A 1 44 ? -3.589 -40.144 55.211 1.00 18.55 ? 44 CYS A CA 1 ATOM 289 C C . CYS A 1 44 ? -3.729 -38.626 55.432 1.00 17.98 ? 44 CYS A C 1 ATOM 290 O O . CYS A 1 44 ? -3.629 -37.827 54.485 1.00 17.07 ? 44 CYS A O 1 ATOM 291 C CB . CYS A 1 44 ? -2.179 -40.534 54.814 1.00 19.17 ? 44 CYS A CB 1 ATOM 292 S SG . CYS A 1 44 ? -0.976 -39.912 55.963 1.00 21.42 ? 44 CYS A SG 1 ATOM 293 N N . TYR A 1 45 ? -3.974 -38.248 56.675 1.00 17.53 ? 45 TYR A N 1 ATOM 294 C CA . TYR A 1 45 ? -4.298 -36.859 57.012 1.00 19.04 ? 45 TYR A CA 1 ATOM 295 C C . TYR A 1 45 ? -3.703 -36.450 58.347 1.00 19.32 ? 45 TYR A C 1 ATOM 296 O O . TYR A 1 45 ? -3.386 -37.304 59.170 1.00 19.99 ? 45 TYR A O 1 ATOM 297 C CB . TYR A 1 45 ? -5.829 -36.670 57.012 1.00 18.88 ? 45 TYR A CB 1 ATOM 298 C CG . TYR A 1 45 ? -6.575 -37.539 57.997 1.00 20.65 ? 45 TYR A CG 1 ATOM 299 C CD1 . TYR A 1 45 ? -6.947 -37.046 59.249 1.00 21.59 ? 45 TYR A CD1 1 ATOM 300 C CD2 . TYR A 1 45 ? -6.918 -38.862 57.677 1.00 22.76 ? 45 TYR A CD2 1 ATOM 301 C CE1 . TYR A 1 45 ? -7.636 -37.838 60.148 1.00 23.53 ? 45 TYR A CE1 1 ATOM 302 C CE2 . TYR A 1 45 ? -7.591 -39.648 58.566 1.00 23.16 ? 45 TYR A CE2 1 ATOM 303 C CZ . TYR A 1 45 ? -7.955 -39.129 59.800 1.00 23.93 ? 45 TYR A CZ 1 ATOM 304 O OH . TYR A 1 45 ? -8.633 -39.940 60.687 1.00 26.67 ? 45 TYR A OH 1 ATOM 305 N N . TYR A 1 46 ? -3.484 -35.149 58.528 1.00 19.87 ? 46 TYR A N 1 ATOM 306 C CA . TYR A 1 46 ? -2.765 -34.649 59.678 1.00 21.85 ? 46 TYR A CA 1 ATOM 307 C C . TYR A 1 46 ? -3.526 -34.863 60.969 1.00 23.85 ? 46 TYR A C 1 ATOM 308 O O . TYR A 1 46 ? -4.769 -34.782 61.008 1.00 23.42 ? 46 TYR A O 1 ATOM 309 C CB . TYR A 1 46 ? -2.392 -33.177 59.527 1.00 21.52 ? 46 TYR A CB 1 ATOM 310 C CG . TYR A 1 46 ? -1.389 -32.913 58.458 1.00 22.26 ? 46 TYR A CG 1 ATOM 311 C CD1 . TYR A 1 46 ? -0.012 -33.168 58.669 1.00 21.82 ? 46 TYR A CD1 1 ATOM 312 C CD2 . TYR A 1 46 ? -1.775 -32.380 57.245 1.00 19.80 ? 46 TYR A CD2 1 ATOM 313 C CE1 . TYR A 1 46 ? 0.925 -32.907 57.676 1.00 21.92 ? 46 TYR A CE1 1 ATOM 314 C CE2 . TYR A 1 46 ? -0.834 -32.135 56.240 1.00 20.85 ? 46 TYR A CE2 1 ATOM 315 C CZ . TYR A 1 46 ? 0.501 -32.400 56.470 1.00 22.18 ? 46 TYR A CZ 1 ATOM 316 O OH . TYR A 1 46 ? 1.419 -32.163 55.473 1.00 22.23 ? 46 TYR A OH 1 ATOM 317 N N . SER A 1 47 ? -2.772 -35.188 62.019 1.00 26.27 ? 47 SER A N 1 ATOM 318 C CA . SER A 1 47 ? -3.359 -35.331 63.345 1.00 30.10 ? 47 SER A CA 1 ATOM 319 C C . SER A 1 47 ? -3.618 -33.978 63.991 1.00 32.79 ? 47 SER A C 1 ATOM 320 O O . SER A 1 47 ? -3.219 -32.929 63.464 1.00 32.42 ? 47 SER A O 1 ATOM 321 C CB . SER A 1 47 ? -2.472 -36.187 64.249 1.00 29.55 ? 47 SER A CB 1 ATOM 322 O OG . SER A 1 47 ? -1.196 -35.570 64.401 1.00 30.13 ? 47 SER A OG 1 ATOM 323 N N . LYS A 1 48 ? -4.253 -34.041 65.163 1.00 36.55 ? 48 LYS A N 1 ATOM 324 C CA . LYS A 1 48 ? -4.766 -32.892 65.920 1.00 40.05 ? 48 LYS A CA 1 ATOM 325 C C . LYS A 1 48 ? -3.700 -31.959 66.477 1.00 41.50 ? 48 LYS A C 1 ATOM 326 O O . LYS A 1 48 ? -4.018 -30.834 66.881 1.00 42.45 ? 48 LYS A O 1 ATOM 327 C CB . LYS A 1 48 ? -5.628 -33.391 67.085 1.00 40.27 ? 48 LYS A CB 1 ATOM 328 C CG . LYS A 1 48 ? -7.120 -33.486 66.797 1.00 42.50 ? 48 LYS A CG 1 ATOM 329 C CD . LYS A 1 48 ? -7.783 -34.596 67.631 1.00 45.51 ? 48 LYS A CD 1 ATOM 330 C CE . LYS A 1 48 ? -7.622 -34.398 69.149 1.00 47.27 ? 48 LYS A CE 1 ATOM 331 N NZ . LYS A 1 48 ? -8.699 -33.529 69.750 1.00 48.90 ? 48 LYS A NZ 1 ATOM 332 N N . ASN A 1 49 ? -2.453 -32.429 66.506 1.00 43.07 ? 49 ASN A N 1 ATOM 333 C CA . ASN A 1 49 ? -1.343 -31.658 67.027 1.00 44.82 ? 49 ASN A CA 1 ATOM 334 C C . ASN A 1 49 ? -0.089 -32.047 66.246 1.00 45.19 ? 49 ASN A C 1 ATOM 335 O O . ASN A 1 49 ? 0.645 -32.946 66.645 1.00 46.42 ? 49 ASN A O 1 ATOM 336 C CB . ASN A 1 49 ? -1.171 -31.966 68.526 1.00 45.37 ? 49 ASN A CB 1 ATOM 337 C CG . ASN A 1 49 ? -1.300 -30.729 69.408 1.00 47.02 ? 49 ASN A CG 1 ATOM 338 O OD1 . ASN A 1 49 ? -0.384 -29.904 69.497 1.00 48.16 ? 49 ASN A OD1 1 ATOM 339 N ND2 . ASN A 1 49 ? -2.442 -30.610 70.087 1.00 48.65 ? 49 ASN A ND2 1 ATOM 340 N N . HIS A 1 50 ? 0.133 -31.406 65.104 1.00 45.38 ? 50 HIS A N 1 ATOM 341 C CA . HIS A 1 50 ? 1.283 -31.734 64.254 1.00 44.91 ? 50 HIS A CA 1 ATOM 342 C C . HIS A 1 50 ? 2.352 -30.633 64.289 1.00 43.57 ? 50 HIS A C 1 ATOM 343 O O . HIS A 1 50 ? 3.548 -30.898 64.070 1.00 44.23 ? 50 HIS A O 1 ATOM 344 C CB . HIS A 1 50 ? 0.839 -31.988 62.792 1.00 45.97 ? 50 HIS A CB 1 ATOM 345 C CG . HIS A 1 50 ? 1.955 -32.411 61.875 1.00 47.83 ? 50 HIS A CG 1 ATOM 346 N ND1 . HIS A 1 50 ? 2.334 -33.730 61.713 1.00 49.88 ? 50 HIS A ND1 1 ATOM 347 C CD2 . HIS A 1 50 ? 2.773 -31.687 61.072 1.00 48.95 ? 50 HIS A CD2 1 ATOM 348 C CE1 . HIS A 1 50 ? 3.341 -33.797 60.859 1.00 49.99 ? 50 HIS A CE1 1 ATOM 349 N NE2 . HIS A 1 50 ? 3.622 -32.572 60.448 1.00 49.49 ? 50 HIS A NE2 1 ATOM 350 N N . SER A 1 51 ? 1.927 -29.404 64.586 1.00 40.51 ? 51 SER A N 1 ATOM 351 C CA . SER A 1 51 ? 2.621 -28.264 64.008 1.00 37.42 ? 51 SER A CA 1 ATOM 352 C C . SER A 1 51 ? 3.425 -27.355 64.949 1.00 34.87 ? 51 SER A C 1 ATOM 353 O O . SER A 1 51 ? 4.560 -27.679 65.310 1.00 35.89 ? 51 SER A O 1 ATOM 354 C CB . SER A 1 51 ? 1.670 -27.457 63.095 1.00 37.92 ? 51 SER A CB 1 ATOM 355 O OG . SER A 1 51 ? 0.684 -26.746 63.818 1.00 36.64 ? 51 SER A OG 1 ATOM 356 N N . TYR A 1 52 ? 2.858 -26.200 65.279 1.00 30.00 ? 52 TYR A N 1 ATOM 357 C CA . TYR A 1 52 ? 3.542 -25.164 66.045 1.00 26.09 ? 52 TYR A CA 1 ATOM 358 C C . TYR A 1 52 ? 2.722 -24.832 67.258 1.00 24.65 ? 52 TYR A C 1 ATOM 359 O O . TYR A 1 52 ? 1.509 -25.041 67.266 1.00 23.87 ? 52 TYR A O 1 ATOM 360 C CB . TYR A 1 52 ? 3.699 -23.902 65.191 1.00 24.78 ? 52 TYR A CB 1 ATOM 361 C CG . TYR A 1 52 ? 4.816 -24.013 64.202 1.00 22.03 ? 52 TYR A CG 1 ATOM 362 C CD1 . TYR A 1 52 ? 4.642 -24.665 62.982 1.00 20.75 ? 52 TYR A CD1 1 ATOM 363 C CD2 . TYR A 1 52 ? 6.068 -23.467 64.481 1.00 21.21 ? 52 TYR A CD2 1 ATOM 364 C CE1 . TYR A 1 52 ? 5.696 -24.764 62.052 1.00 21.65 ? 52 TYR A CE1 1 ATOM 365 C CE2 . TYR A 1 52 ? 7.137 -23.586 63.562 1.00 22.79 ? 52 TYR A CE2 1 ATOM 366 C CZ . TYR A 1 52 ? 6.939 -24.230 62.367 1.00 23.56 ? 52 TYR A CZ 1 ATOM 367 O OH . TYR A 1 52 ? 7.987 -24.337 61.472 1.00 23.79 ? 52 TYR A OH 1 ATOM 368 N N . HIS A 1 53 ? 3.382 -24.339 68.293 1.00 23.66 ? 53 HIS A N 1 ATOM 369 C CA . HIS A 1 53 ? 2.683 -23.777 69.433 1.00 23.34 ? 53 HIS A CA 1 ATOM 370 C C . HIS A 1 53 ? 3.206 -22.392 69.689 1.00 22.32 ? 53 HIS A C 1 ATOM 371 O O . HIS A 1 53 ? 4.338 -22.061 69.347 1.00 20.43 ? 53 HIS A O 1 ATOM 372 C CB . HIS A 1 53 ? 2.790 -24.649 70.690 1.00 24.23 ? 53 HIS A CB 1 ATOM 373 C CG . HIS A 1 53 ? 4.194 -24.912 71.131 1.00 26.78 ? 53 HIS A CG 1 ATOM 374 N ND1 . HIS A 1 53 ? 4.810 -24.190 72.132 1.00 32.46 ? 53 HIS A ND1 1 ATOM 375 C CD2 . HIS A 1 53 ? 5.106 -25.810 70.701 1.00 29.44 ? 53 HIS A CD2 1 ATOM 376 C CE1 . HIS A 1 53 ? 6.045 -24.631 72.296 1.00 30.35 ? 53 HIS A CE1 1 ATOM 377 N NE2 . HIS A 1 53 ? 6.254 -25.607 71.433 1.00 30.52 ? 53 HIS A NE2 1 ATOM 378 N N . VAL A 1 54 ? 2.365 -21.555 70.276 1.00 20.84 ? 54 VAL A N 1 ATOM 379 C CA . VAL A 1 54 ? 2.813 -20.240 70.684 1.00 20.58 ? 54 VAL A CA 1 ATOM 380 C C . VAL A 1 54 ? 3.689 -20.420 71.915 1.00 21.06 ? 54 VAL A C 1 ATOM 381 O O . VAL A 1 54 ? 3.300 -21.102 72.863 1.00 21.11 ? 54 VAL A O 1 ATOM 382 C CB . VAL A 1 54 ? 1.608 -19.322 70.987 1.00 20.16 ? 54 VAL A CB 1 ATOM 383 C CG1 . VAL A 1 54 ? 2.046 -18.034 71.664 1.00 20.32 ? 54 VAL A CG1 1 ATOM 384 C CG2 . VAL A 1 54 ? 0.878 -19.012 69.664 1.00 20.54 ? 54 VAL A CG2 1 ATOM 385 N N . GLU A 1 55 ? 4.873 -19.818 71.873 1.00 21.92 ? 55 GLU A N 1 ATOM 386 C CA . GLU A 1 55 ? 5.775 -19.766 73.002 1.00 24.54 ? 55 GLU A CA 1 ATOM 387 C C . GLU A 1 55 ? 5.639 -18.418 73.729 1.00 23.98 ? 55 GLU A C 1 ATOM 388 O O . GLU A 1 55 ? 5.926 -17.345 73.162 1.00 24.79 ? 55 GLU A O 1 ATOM 389 C CB . GLU A 1 55 ? 7.214 -19.976 72.516 1.00 25.41 ? 55 GLU A CB 1 ATOM 390 C CG . GLU A 1 55 ? 8.270 -20.086 73.623 1.00 32.14 ? 55 GLU A CG 1 ATOM 391 C CD . GLU A 1 55 ? 8.167 -21.378 74.440 1.00 38.89 ? 55 GLU A CD 1 ATOM 392 O OE1 . GLU A 1 55 ? 7.911 -22.465 73.866 1.00 42.94 ? 55 GLU A OE1 1 ATOM 393 O OE2 . GLU A 1 55 ? 8.363 -21.309 75.671 1.00 43.85 ? 55 GLU A OE2 1 ATOM 394 N N . GLY A 1 56 ? 5.185 -18.474 74.977 1.00 23.13 ? 56 GLY A N 1 ATOM 395 C CA . GLY A 1 56 ? 5.135 -17.287 75.797 1.00 22.97 ? 56 GLY A CA 1 ATOM 396 C C . GLY A 1 56 ? 3.960 -16.402 75.421 1.00 22.17 ? 56 GLY A C 1 ATOM 397 O O . GLY A 1 56 ? 2.950 -16.895 74.907 1.00 22.43 ? 56 GLY A O 1 ATOM 398 N N . ASN A 1 57 ? 4.078 -15.113 75.689 1.00 21.00 ? 57 ASN A N 1 ATOM 399 C CA . ASN A 1 57 ? 2.942 -14.196 75.474 1.00 21.22 ? 57 ASN A CA 1 ATOM 400 C C . ASN A 1 57 ? 3.026 -13.526 74.130 1.00 20.22 ? 57 ASN A C 1 ATOM 401 O O . ASN A 1 57 ? 4.119 -13.313 73.571 1.00 19.29 ? 57 ASN A O 1 ATOM 402 C CB . ASN A 1 57 ? 2.845 -13.129 76.570 1.00 21.19 ? 57 ASN A CB 1 ATOM 403 C CG . ASN A 1 57 ? 2.608 -13.718 77.942 1.00 21.63 ? 57 ASN A CG 1 ATOM 404 O OD1 . ASN A 1 57 ? 2.051 -14.788 78.075 1.00 20.77 ? 57 ASN A OD1 1 ATOM 405 N ND2 . ASN A 1 57 ? 3.035 -13.006 78.969 1.00 24.71 ? 57 ASN A ND2 1 ATOM 406 N N . LEU A 1 58 ? 1.862 -13.186 73.601 1.00 18.02 ? 58 LEU A N 1 ATOM 407 C CA . LEU A 1 58 ? 1.781 -12.252 72.506 1.00 17.88 ? 58 LEU A CA 1 ATOM 408 C C . LEU A 1 58 ? 2.203 -10.892 73.001 1.00 17.21 ? 58 LEU A C 1 ATOM 409 O O . LEU A 1 58 ? 2.002 -10.550 74.169 1.00 18.02 ? 58 LEU A O 1 ATOM 410 C CB . LEU A 1 58 ? 0.329 -12.170 71.920 1.00 17.64 ? 58 LEU A CB 1 ATOM 411 C CG . LEU A 1 58 ? -0.045 -13.218 70.860 1.00 18.38 ? 58 LEU A CG 1 ATOM 412 C CD1 . LEU A 1 58 ? 0.290 -14.615 71.328 1.00 17.05 ? 58 LEU A CD1 1 ATOM 413 C CD2 . LEU A 1 58 ? -1.555 -13.172 70.489 1.00 18.37 ? 58 LEU A CD2 1 ATOM 414 N N . VAL A 1 59 ? 2.776 -10.109 72.105 1.00 17.89 ? 59 VAL A N 1 ATOM 415 C CA . VAL A 1 59 ? 3.210 -8.761 72.413 1.00 19.06 ? 59 VAL A CA 1 ATOM 416 C C . VAL A 1 59 ? 2.440 -7.747 71.590 1.00 18.50 ? 59 VAL A C 1 ATOM 417 O O . VAL A 1 59 ? 2.475 -7.785 70.369 1.00 18.35 ? 59 VAL A O 1 ATOM 418 C CB . VAL A 1 59 ? 4.704 -8.595 72.048 1.00 19.10 ? 59 VAL A CB 1 ATOM 419 C CG1 . VAL A 1 59 ? 5.206 -7.235 72.491 1.00 21.58 ? 59 VAL A CG1 1 ATOM 420 C CG2 . VAL A 1 59 ? 5.498 -9.712 72.691 1.00 22.34 ? 59 VAL A CG2 1 ATOM 421 N N . ASN A 1 60 ? 1.777 -6.808 72.254 1.00 19.43 ? 60 ASN A N 1 ATOM 422 C CA . ASN A 1 60 ? 1.241 -5.639 71.555 1.00 19.36 ? 60 ASN A CA 1 ATOM 423 C C . ASN A 1 60 ? 2.274 -4.749 70.898 1.00 20.09 ? 60 ASN A C 1 ATOM 424 O O . ASN A 1 60 ? 3.285 -4.386 71.502 1.00 20.50 ? 60 ASN A O 1 ATOM 425 C CB . ASN A 1 60 ? 0.410 -4.772 72.492 1.00 20.41 ? 60 ASN A CB 1 ATOM 426 C CG . ASN A 1 60 ? -0.833 -5.479 72.953 1.00 19.85 ? 60 ASN A CG 1 ATOM 427 O OD1 . ASN A 1 60 ? -1.860 -5.510 72.253 1.00 26.04 ? 60 ASN A OD1 1 ATOM 428 N ND2 . ASN A 1 60 ? -0.756 -6.060 74.111 1.00 21.67 ? 60 ASN A ND2 1 ATOM 429 N N . THR A 1 61 ? 1.998 -4.388 69.654 1.00 18.54 ? 61 THR A N 1 ATOM 430 C CA . THR A 1 61 ? 2.818 -3.459 68.913 1.00 18.86 ? 61 THR A CA 1 ATOM 431 C C . THR A 1 61 ? 1.897 -2.290 68.551 1.00 19.30 ? 61 THR A C 1 ATOM 432 O O . THR A 1 61 ? 0.688 -2.398 68.745 1.00 19.22 ? 61 THR A O 1 ATOM 433 C CB . THR A 1 61 ? 3.329 -4.091 67.645 1.00 18.92 ? 61 THR A CB 1 ATOM 434 O OG1 . THR A 1 61 ? 2.218 -4.418 66.785 1.00 20.70 ? 61 THR A OG1 1 ATOM 435 C CG2 . THR A 1 61 ? 4.184 -5.372 67.921 1.00 19.00 ? 61 THR A CG2 1 ATOM 436 N N . ASN A 1 62 ? 2.439 -1.204 68.012 1.00 19.85 ? 62 ASN A N 1 ATOM 437 C CA . ASN A 1 62 ? 1.573 -0.103 67.553 1.00 21.49 ? 62 ASN A CA 1 ATOM 438 C C . ASN A 1 62 ? 0.548 -0.526 66.492 1.00 20.35 ? 62 ASN A C 1 ATOM 439 O O . ASN A 1 62 ? -0.563 -0.022 66.482 1.00 20.20 ? 62 ASN A O 1 ATOM 440 C CB . ASN A 1 62 ? 2.389 1.071 67.036 1.00 22.27 ? 62 ASN A CB 1 ATOM 441 C CG . ASN A 1 62 ? 3.130 1.802 68.154 1.00 26.71 ? 62 ASN A CG 1 ATOM 442 O OD1 . ASN A 1 62 ? 4.246 2.275 67.951 1.00 31.20 ? 62 ASN A OD1 1 ATOM 443 N ND2 . ASN A 1 62 ? 2.515 1.894 69.324 1.00 26.05 ? 62 ASN A ND2 1 ATOM 444 N N . ALA A 1 63 ? 0.947 -1.442 65.608 1.00 19.17 ? 63 ALA A N 1 ATOM 445 C CA . ALA A 1 63 ? 0.102 -1.929 64.489 1.00 19.04 ? 63 ALA A CA 1 ATOM 446 C C . ALA A 1 63 ? -0.851 -3.082 64.826 1.00 18.37 ? 63 ALA A C 1 ATOM 447 O O . ALA A 1 63 ? -1.855 -3.279 64.149 1.00 19.32 ? 63 ALA A O 1 ATOM 448 C CB . ALA A 1 63 ? 1.000 -2.306 63.295 1.00 19.52 ? 63 ALA A CB 1 ATOM 449 N N . GLY A 1 64 ? -0.534 -3.853 65.854 1.00 17.57 ? 64 GLY A N 1 ATOM 450 C CA . GLY A 1 64 ? -1.265 -5.075 66.183 1.00 17.63 ? 64 GLY A CA 1 ATOM 451 C C . GLY A 1 64 ? -0.555 -5.880 67.268 1.00 17.22 ? 64 GLY A C 1 ATOM 452 O O . GLY A 1 64 ? -0.537 -5.490 68.431 1.00 16.11 ? 64 GLY A O 1 ATOM 453 N N . PHE A 1 65 ? 0.038 -7.007 66.889 1.00 16.90 ? 65 PHE A N 1 ATOM 454 C CA . PHE A 1 65 ? 0.736 -7.858 67.862 1.00 17.39 ? 65 PHE A CA 1 ATOM 455 C C . PHE A 1 65 ? 1.714 -8.785 67.152 1.00 17.59 ? 65 PHE A C 1 ATOM 456 O O . PHE A 1 65 ? 1.624 -8.986 65.937 1.00 16.63 ? 65 PHE A O 1 ATOM 457 C CB . PHE A 1 65 ? -0.250 -8.686 68.719 1.00 17.92 ? 65 PHE A CB 1 ATOM 458 C CG . PHE A 1 65 ? -1.056 -9.682 67.926 1.00 20.12 ? 65 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 65 ? -0.540 -10.961 67.648 1.00 18.87 ? 65 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 65 ? -2.351 -9.340 67.461 1.00 22.34 ? 65 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 65 ? -1.265 -11.879 66.912 1.00 20.51 ? 65 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 65 ? -3.100 -10.253 66.739 1.00 20.64 ? 65 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 65 ? -2.552 -11.525 66.450 1.00 18.37 ? 65 PHE A CZ 1 ATOM 464 N N . THR A 1 66 ? 2.669 -9.316 67.914 1.00 17.53 ? 66 THR A N 1 ATOM 465 C CA . THR A 1 66 ? 3.547 -10.391 67.422 1.00 17.83 ? 66 THR A CA 1 ATOM 466 C C . THR A 1 66 ? 3.452 -11.581 68.381 1.00 17.25 ? 66 THR A C 1 ATOM 467 O O . THR A 1 66 ? 3.082 -11.426 69.553 1.00 17.85 ? 66 THR A O 1 ATOM 468 C CB . THR A 1 66 ? 5.023 -9.912 67.253 1.00 18.65 ? 66 THR A CB 1 ATOM 469 O OG1 . THR A 1 66 ? 5.482 -9.323 68.467 1.00 19.33 ? 66 THR A OG1 1 ATOM 470 C CG2 . THR A 1 66 ? 5.175 -8.888 66.129 1.00 18.44 ? 66 THR A CG2 1 ATOM 471 N N . ALA A 1 67 ? 3.781 -12.773 67.876 1.00 16.68 ? 67 ALA A N 1 ATOM 472 C CA . ALA A 1 67 ? 3.811 -13.992 68.634 1.00 17.33 ? 67 ALA A CA 1 ATOM 473 C C . ALA A 1 67 ? 4.996 -14.791 68.117 1.00 18.27 ? 67 ALA A C 1 ATOM 474 O O . ALA A 1 67 ? 5.313 -14.773 66.913 1.00 18.76 ? 67 ALA A O 1 ATOM 475 C CB . ALA A 1 67 ? 2.558 -14.801 68.386 1.00 17.16 ? 67 ALA A CB 1 ATOM 476 N N . ARG A 1 68 ? 5.658 -15.459 69.032 1.00 18.27 ? 68 ARG A N 1 ATOM 477 C CA . ARG A 1 68 ? 6.685 -16.433 68.638 1.00 19.80 ? 68 ARG A CA 1 ATOM 478 C C . ARG A 1 68 ? 6.062 -17.785 68.614 1.00 19.65 ? 68 ARG A C 1 ATOM 479 O O . ARG A 1 68 ? 5.397 -18.163 69.581 1.00 19.91 ? 68 ARG A O 1 ATOM 480 C CB . ARG A 1 68 ? 7.808 -16.421 69.654 1.00 20.05 ? 68 ARG A CB 1 ATOM 481 C CG . ARG A 1 68 ? 8.565 -15.149 69.663 1.00 25.05 ? 68 ARG A CG 1 ATOM 482 C CD . ARG A 1 68 ? 9.717 -15.315 70.674 1.00 33.67 ? 68 ARG A CD 1 ATOM 483 N NE . ARG A 1 68 ? 10.520 -14.112 70.852 1.00 41.87 ? 68 ARG A NE 1 ATOM 484 C CZ . ARG A 1 68 ? 11.353 -13.920 71.878 1.00 46.51 ? 68 ARG A CZ 1 ATOM 485 N NH1 . ARG A 1 68 ? 11.472 -14.844 72.832 1.00 47.33 ? 68 ARG A NH1 1 ATOM 486 N NH2 . ARG A 1 68 ? 12.063 -12.799 71.960 1.00 47.92 ? 68 ARG A NH2 1 ATOM 487 N N . LEU A 1 69 ? 6.259 -18.506 67.508 1.00 18.83 ? 69 LEU A N 1 ATOM 488 C CA . LEU A 1 69 ? 5.769 -19.832 67.358 1.00 20.28 ? 69 LEU A CA 1 ATOM 489 C C . LEU A 1 69 ? 6.963 -20.780 67.400 1.00 22.62 ? 69 LEU A C 1 ATOM 490 O O . LEU A 1 69 ? 8.006 -20.512 66.786 1.00 22.00 ? 69 LEU A O 1 ATOM 491 C CB . LEU A 1 69 ? 5.026 -19.991 66.024 1.00 19.88 ? 69 LEU A CB 1 ATOM 492 C CG . LEU A 1 69 ? 3.931 -18.992 65.668 1.00 20.73 ? 69 LEU A CG 1 ATOM 493 C CD1 . LEU A 1 69 ? 3.177 -19.505 64.441 1.00 18.51 ? 69 LEU A CD1 1 ATOM 494 C CD2 . LEU A 1 69 ? 3.025 -18.762 66.850 1.00 23.85 ? 69 LEU A CD2 1 ATOM 495 N N . LYS A 1 70 ? 6.806 -21.866 68.133 1.00 24.50 ? 70 LYS A N 1 ATOM 496 C CA . LYS A 1 70 ? 7.892 -22.829 68.261 1.00 27.87 ? 70 LYS A CA 1 ATOM 497 C C . LYS A 1 70 ? 7.451 -24.138 67.654 1.00 28.87 ? 70 LYS A C 1 ATOM 498 O O . LYS A 1 70 ? 6.348 -24.625 67.907 1.00 27.77 ? 70 LYS A O 1 ATOM 499 C CB . LYS A 1 70 ? 8.269 -22.964 69.744 1.00 27.92 ? 70 LYS A CB 1 ATOM 500 C CG . LYS A 1 70 ? 9.523 -23.733 70.083 1.00 32.78 ? 70 LYS A CG 1 ATOM 501 C CD . LYS A 1 70 ? 9.910 -23.353 71.529 1.00 36.19 ? 70 LYS A CD 1 ATOM 502 C CE . LYS A 1 70 ? 11.125 -24.111 72.062 1.00 40.69 ? 70 LYS A CE 1 ATOM 503 N NZ . LYS A 1 70 ? 11.428 -23.632 73.443 1.00 39.68 ? 70 LYS A NZ 1 ATOM 504 N N . ASN A 1 71 ? 8.327 -24.702 66.834 1.00 31.65 ? 71 ASN A N 1 ATOM 505 C CA . ASN A 1 71 ? 8.076 -25.982 66.205 1.00 35.24 ? 71 ASN A CA 1 ATOM 506 C C . ASN A 1 71 ? 8.005 -27.106 67.246 1.00 37.49 ? 71 ASN A C 1 ATOM 507 O O . ASN A 1 71 ? 8.911 -27.256 68.062 1.00 38.20 ? 71 ASN A O 1 ATOM 508 C CB . ASN A 1 71 ? 9.175 -26.250 65.162 1.00 34.87 ? 71 ASN A CB 1 ATOM 509 C CG . ASN A 1 71 ? 8.923 -27.481 64.354 1.00 36.65 ? 71 ASN A CG 1 ATOM 510 O OD1 . ASN A 1 71 ? 7.828 -27.683 63.810 1.00 36.18 ? 71 ASN A OD1 1 ATOM 511 N ND2 . ASN A 1 71 ? 9.949 -28.336 64.262 1.00 38.77 ? 71 ASN A ND2 1 ATOM 512 N N . LEU A 1 72 ? 6.901 -27.849 67.235 1.00 40.71 ? 72 LEU A N 1 ATOM 513 C CA . LEU A 1 72 ? 6.805 -29.129 67.944 1.00 43.43 ? 72 LEU A CA 1 ATOM 514 C C . LEU A 1 72 ? 7.576 -30.200 67.148 1.00 45.14 ? 72 LEU A C 1 ATOM 515 O O . LEU A 1 72 ? 7.487 -30.233 65.923 1.00 45.58 ? 72 LEU A O 1 ATOM 516 C CB . LEU A 1 72 ? 5.340 -29.578 68.066 1.00 43.58 ? 72 LEU A CB 1 ATOM 517 C CG . LEU A 1 72 ? 4.317 -29.170 69.139 1.00 43.53 ? 72 LEU A CG 1 ATOM 518 C CD1 . LEU A 1 72 ? 4.895 -29.062 70.566 1.00 44.18 ? 72 LEU A CD1 1 ATOM 519 C CD2 . LEU A 1 72 ? 3.597 -27.915 68.738 1.00 43.92 ? 72 LEU A CD2 1 ATOM 520 N N . PRO A 1 73 ? 8.287 -31.110 67.834 1.00 46.80 ? 73 PRO A N 1 ATOM 521 C CA . PRO A 1 73 ? 9.102 -32.124 67.132 1.00 48.03 ? 73 PRO A CA 1 ATOM 522 C C . PRO A 1 73 ? 8.352 -32.868 66.001 1.00 48.78 ? 73 PRO A C 1 ATOM 523 O O . PRO A 1 73 ? 7.252 -33.387 66.228 1.00 48.72 ? 73 PRO A O 1 ATOM 524 C CB . PRO A 1 73 ? 9.503 -33.101 68.262 1.00 47.95 ? 73 PRO A CB 1 ATOM 525 C CG . PRO A 1 73 ? 8.551 -32.771 69.438 1.00 48.41 ? 73 PRO A CG 1 ATOM 526 C CD . PRO A 1 73 ? 8.339 -31.283 69.298 1.00 47.23 ? 73 PRO A CD 1 ATOM 527 N N . SER A 1 74 ? 8.933 -32.880 64.796 1.00 49.60 ? 74 SER A N 1 ATOM 528 C CA . SER A 1 74 ? 8.356 -33.578 63.624 1.00 50.63 ? 74 SER A CA 1 ATOM 529 C C . SER A 1 74 ? 9.398 -33.981 62.573 1.00 50.79 ? 74 SER A C 1 ATOM 530 O O . SER A 1 74 ? 10.321 -33.218 62.298 1.00 51.00 ? 74 SER A O 1 ATOM 531 C CB . SER A 1 74 ? 7.266 -32.735 62.959 1.00 50.79 ? 74 SER A CB 1 ATOM 532 O OG . SER A 1 74 ? 5.987 -33.295 63.206 1.00 52.37 ? 74 SER A OG 1 ATOM 533 N N . SER A 1 75 ? 9.229 -35.164 61.970 1.00 51.14 ? 75 SER A N 1 ATOM 534 C CA . SER A 1 75 ? 10.217 -35.691 61.005 1.00 51.13 ? 75 SER A CA 1 ATOM 535 C C . SER A 1 75 ? 10.244 -34.849 59.717 1.00 50.72 ? 75 SER A C 1 ATOM 536 O O . SER A 1 75 ? 9.197 -34.377 59.276 1.00 50.98 ? 75 SER A O 1 ATOM 537 C CB . SER A 1 75 ? 10.033 -37.205 60.747 1.00 51.21 ? 75 SER A CB 1 ATOM 538 O OG . SER A 1 75 ? 10.994 -37.983 61.488 1.00 51.84 ? 75 SER A OG 1 ATOM 539 N N . PRO A 1 76 ? 11.446 -34.625 59.137 1.00 50.11 ? 76 PRO A N 1 ATOM 540 C CA . PRO A 1 76 ? 11.504 -33.676 58.036 1.00 49.58 ? 76 PRO A CA 1 ATOM 541 C C . PRO A 1 76 ? 11.094 -34.335 56.714 1.00 48.73 ? 76 PRO A C 1 ATOM 542 O O . PRO A 1 76 ? 11.841 -35.162 56.172 1.00 49.47 ? 76 PRO A O 1 ATOM 543 C CB . PRO A 1 76 ? 12.976 -33.237 58.024 1.00 49.84 ? 76 PRO A CB 1 ATOM 544 C CG . PRO A 1 76 ? 13.737 -34.362 58.632 1.00 49.73 ? 76 PRO A CG 1 ATOM 545 C CD . PRO A 1 76 ? 12.767 -35.225 59.417 1.00 50.25 ? 76 PRO A CD 1 ATOM 546 N N . VAL A 1 77 ? 9.905 -33.986 56.218 1.00 47.19 ? 77 VAL A N 1 ATOM 547 C CA . VAL A 1 77 ? 9.382 -34.579 54.985 1.00 45.63 ? 77 VAL A CA 1 ATOM 548 C C . VAL A 1 77 ? 9.931 -33.880 53.736 1.00 44.51 ? 77 VAL A C 1 ATOM 549 O O . VAL A 1 77 ? 10.498 -34.529 52.840 1.00 44.27 ? 77 VAL A O 1 ATOM 550 C CB . VAL A 1 77 ? 7.834 -34.580 54.949 1.00 45.87 ? 77 VAL A CB 1 ATOM 551 C CG1 . VAL A 1 77 ? 7.344 -35.212 53.666 1.00 45.88 ? 77 VAL A CG1 1 ATOM 552 C CG2 . VAL A 1 77 ? 7.261 -35.312 56.161 1.00 46.19 ? 77 VAL A CG2 1 ATOM 553 N N . PHE A 1 78 ? 9.745 -32.562 53.667 1.00 42.41 ? 78 PHE A N 1 ATOM 554 C CA . PHE A 1 78 ? 10.203 -31.793 52.514 1.00 41.22 ? 78 PHE A CA 1 ATOM 555 C C . PHE A 1 78 ? 11.365 -30.900 52.910 1.00 41.33 ? 78 PHE A C 1 ATOM 556 O O . PHE A 1 78 ? 11.511 -29.768 52.435 1.00 40.89 ? 78 PHE A O 1 ATOM 557 C CB . PHE A 1 78 ? 9.048 -31.028 51.882 1.00 39.84 ? 78 PHE A CB 1 ATOM 558 C CG . PHE A 1 78 ? 7.917 -31.914 51.472 1.00 38.21 ? 78 PHE A CG 1 ATOM 559 C CD1 . PHE A 1 78 ? 6.682 -31.816 52.088 1.00 37.11 ? 78 PHE A CD1 1 ATOM 560 C CD2 . PHE A 1 78 ? 8.104 -32.885 50.501 1.00 36.09 ? 78 PHE A CD2 1 ATOM 561 C CE1 . PHE A 1 78 ? 5.629 -32.645 51.718 1.00 37.49 ? 78 PHE A CE1 1 ATOM 562 C CE2 . PHE A 1 78 ? 7.059 -33.731 50.131 1.00 37.48 ? 78 PHE A CE2 1 ATOM 563 C CZ . PHE A 1 78 ? 5.822 -33.606 50.738 1.00 37.22 ? 78 PHE A CZ 1 ATOM 564 N N . GLY A 1 79 ? 12.188 -31.445 53.802 1.00 41.85 ? 79 GLY A N 1 ATOM 565 C CA . GLY A 1 79 ? 13.454 -30.846 54.167 1.00 42.28 ? 79 GLY A CA 1 ATOM 566 C C . GLY A 1 79 ? 13.428 -29.881 55.329 1.00 42.44 ? 79 GLY A C 1 ATOM 567 O O . GLY A 1 79 ? 12.690 -30.071 56.304 1.00 42.81 ? 79 GLY A O 1 ATOM 568 N N . SER A 1 80 ? 14.242 -28.834 55.180 1.00 42.73 ? 80 SER A N 1 ATOM 569 C CA . SER A 1 80 ? 14.712 -27.982 56.270 1.00 42.06 ? 80 SER A CA 1 ATOM 570 C C . SER A 1 80 ? 13.625 -27.131 56.939 1.00 41.14 ? 80 SER A C 1 ATOM 571 O O . SER A 1 80 ? 13.320 -26.021 56.498 1.00 40.46 ? 80 SER A O 1 ATOM 572 C CB . SER A 1 80 ? 15.879 -27.119 55.781 1.00 42.73 ? 80 SER A CB 1 ATOM 573 O OG . SER A 1 80 ? 16.887 -27.939 55.198 1.00 44.60 ? 80 SER A OG 1 ATOM 574 N N . ASN A 1 81 ? 13.089 -27.689 58.023 1.00 39.52 ? 81 ASN A N 1 ATOM 575 C CA . ASN A 1 81 ? 12.019 -27.127 58.827 1.00 38.30 ? 81 ASN A CA 1 ATOM 576 C C . ASN A 1 81 ? 12.407 -25.852 59.605 1.00 37.38 ? 81 ASN A C 1 ATOM 577 O O . ASN A 1 81 ? 13.573 -25.668 59.952 1.00 37.25 ? 81 ASN A O 1 ATOM 578 C CB . ASN A 1 81 ? 11.557 -28.204 59.787 1.00 38.85 ? 81 ASN A CB 1 ATOM 579 C CG . ASN A 1 81 ? 10.147 -28.003 60.243 1.00 40.29 ? 81 ASN A CG 1 ATOM 580 O OD1 . ASN A 1 81 ? 9.819 -26.987 60.842 1.00 42.46 ? 81 ASN A OD1 1 ATOM 581 N ND2 . ASN A 1 81 ? 9.292 -28.988 59.976 1.00 44.35 ? 81 ASN A ND2 1 ATOM 582 N N . VAL A 1 82 ? 11.445 -24.963 59.869 1.00 35.11 ? 82 VAL A N 1 ATOM 583 C CA . VAL A 1 82 ? 11.774 -23.693 60.536 1.00 33.02 ? 82 VAL A CA 1 ATOM 584 C C . VAL A 1 82 ? 11.378 -23.760 62.003 1.00 32.78 ? 82 VAL A C 1 ATOM 585 O O . VAL A 1 82 ? 10.188 -23.844 62.327 1.00 32.91 ? 82 VAL A O 1 ATOM 586 C CB . VAL A 1 82 ? 11.180 -22.465 59.777 1.00 33.34 ? 82 VAL A CB 1 ATOM 587 C CG1 . VAL A 1 82 ? 11.285 -21.201 60.588 1.00 32.53 ? 82 VAL A CG1 1 ATOM 588 C CG2 . VAL A 1 82 ? 11.872 -22.301 58.431 1.00 31.69 ? 82 VAL A CG2 1 ATOM 589 N N . ASP A 1 83 ? 12.382 -23.756 62.883 1.00 31.57 ? 83 ASP A N 1 ATOM 590 C CA . ASP A 1 83 ? 12.178 -24.015 64.320 1.00 32.13 ? 83 ASP A CA 1 ATOM 591 C C . ASP A 1 83 ? 11.433 -22.903 65.060 1.00 29.72 ? 83 ASP A C 1 ATOM 592 O O . ASP A 1 83 ? 10.585 -23.178 65.894 1.00 30.84 ? 83 ASP A O 1 ATOM 593 C CB . ASP A 1 83 ? 13.513 -24.207 65.033 1.00 32.68 ? 83 ASP A CB 1 ATOM 594 C CG . ASP A 1 83 ? 14.028 -25.623 64.955 1.00 37.36 ? 83 ASP A CG 1 ATOM 595 O OD1 . ASP A 1 83 ? 13.345 -26.526 64.374 1.00 41.06 ? 83 ASP A OD1 1 ATOM 596 O OD2 . ASP A 1 83 ? 15.143 -25.821 65.501 1.00 40.77 ? 83 ASP A OD2 1 ATOM 597 N N . ASN A 1 84 ? 11.790 -21.660 64.779 1.00 27.63 ? 84 ASN A N 1 ATOM 598 C CA . ASN A 1 84 ? 11.137 -20.518 65.398 1.00 26.03 ? 84 ASN A CA 1 ATOM 599 C C . ASN A 1 84 ? 10.520 -19.647 64.348 1.00 23.59 ? 84 ASN A C 1 ATOM 600 O O . ASN A 1 84 ? 11.214 -19.091 63.504 1.00 23.11 ? 84 ASN A O 1 ATOM 601 C CB . ASN A 1 84 ? 12.132 -19.701 66.192 1.00 26.08 ? 84 ASN A CB 1 ATOM 602 C CG . ASN A 1 84 ? 12.779 -20.505 67.288 1.00 29.49 ? 84 ASN A CG 1 ATOM 603 O OD1 . ASN A 1 84 ? 13.863 -21.067 67.097 1.00 33.09 ? 84 ASN A OD1 1 ATOM 604 N ND2 . ASN A 1 84 ? 12.110 -20.605 68.424 1.00 29.29 ? 84 ASN A ND2 1 ATOM 605 N N . VAL A 1 85 ? 9.202 -19.547 64.410 1.00 22.38 ? 85 VAL A N 1 ATOM 606 C CA . VAL A 1 85 ? 8.449 -18.783 63.440 1.00 19.43 ? 85 VAL A CA 1 ATOM 607 C C . VAL A 1 85 ? 7.963 -17.516 64.154 1.00 19.04 ? 85 VAL A C 1 ATOM 608 O O . VAL A 1 85 ? 7.636 -17.569 65.348 1.00 18.90 ? 85 VAL A O 1 ATOM 609 C CB . VAL A 1 85 ? 7.289 -19.659 62.834 1.00 19.77 ? 85 VAL A CB 1 ATOM 610 C CG1 . VAL A 1 85 ? 6.247 -18.785 62.131 1.00 17.74 ? 85 VAL A CG1 1 ATOM 611 C CG2 . VAL A 1 85 ? 7.852 -20.609 61.800 1.00 19.50 ? 85 VAL A CG2 1 ATOM 612 N N . LEU A 1 86 ? 7.966 -16.381 63.457 1.00 17.43 ? 86 LEU A N 1 ATOM 613 C CA . LEU A 1 86 ? 7.438 -15.149 64.015 1.00 17.89 ? 86 LEU A CA 1 ATOM 614 C C . LEU A 1 86 ? 6.100 -14.888 63.324 1.00 17.54 ? 86 LEU A C 1 ATOM 615 O O . LEU A 1 86 ? 5.990 -14.968 62.112 1.00 17.32 ? 86 LEU A O 1 ATOM 616 C CB . LEU A 1 86 ? 8.386 -13.960 63.790 1.00 18.44 ? 86 LEU A CB 1 ATOM 617 C CG . LEU A 1 86 ? 7.891 -12.602 64.313 1.00 19.11 ? 86 LEU A CG 1 ATOM 618 C CD1 . LEU A 1 86 ? 7.990 -12.469 65.843 1.00 20.22 ? 86 LEU A CD1 1 ATOM 619 C CD2 . LEU A 1 86 ? 8.541 -11.451 63.614 1.00 22.32 ? 86 LEU A CD2 1 ATOM 620 N N . LEU A 1 87 ? 5.088 -14.579 64.118 1.00 18.24 ? 87 LEU A N 1 ATOM 621 C CA . LEU A 1 87 ? 3.835 -14.079 63.582 1.00 17.52 ? 87 LEU A CA 1 ATOM 622 C C . LEU A 1 87 ? 3.772 -12.575 63.852 1.00 16.69 ? 87 LEU A C 1 ATOM 623 O O . LEU A 1 87 ? 3.946 -12.135 64.992 1.00 15.68 ? 87 LEU A O 1 ATOM 624 C CB . LEU A 1 87 ? 2.658 -14.818 64.268 1.00 17.24 ? 87 LEU A CB 1 ATOM 625 C CG . LEU A 1 87 ? 1.270 -14.214 63.997 1.00 19.37 ? 87 LEU A CG 1 ATOM 626 C CD1 . LEU A 1 87 ? 0.930 -14.300 62.530 1.00 17.18 ? 87 LEU A CD1 1 ATOM 627 C CD2 . LEU A 1 87 ? 0.213 -14.955 64.800 1.00 17.68 ? 87 LEU A CD2 1 ATOM 628 N N . THR A 1 88 ? 3.533 -11.787 62.805 1.00 17.71 ? 88 THR A N 1 ATOM 629 C CA . THR A 1 88 ? 3.380 -10.351 62.905 1.00 17.66 ? 88 THR A CA 1 ATOM 630 C C . THR A 1 88 ? 2.003 -10.063 62.337 1.00 17.67 ? 88 THR A C 1 ATOM 631 O O . THR A 1 88 ? 1.730 -10.410 61.198 1.00 16.44 ? 88 THR A O 1 ATOM 632 C CB . THR A 1 88 ? 4.397 -9.601 62.074 1.00 19.04 ? 88 THR A CB 1 ATOM 633 O OG1 . THR A 1 88 ? 5.729 -9.952 62.495 1.00 21.31 ? 88 THR A OG1 1 ATOM 634 C CG2 . THR A 1 88 ? 4.219 -8.094 62.221 1.00 19.08 ? 88 THR A CG2 1 ATOM 635 N N . ALA A 1 89 ? 1.168 -9.403 63.126 1.00 17.22 ? 89 ALA A N 1 ATOM 636 C CA . ALA A 1 89 ? -0.214 -9.132 62.740 1.00 16.74 ? 89 ALA A CA 1 ATOM 637 C C . ALA A 1 89 ? -0.402 -7.629 62.783 1.00 16.63 ? 89 ALA A C 1 ATOM 638 O O . ALA A 1 89 ? 0.145 -6.958 63.692 1.00 15.50 ? 89 ALA A O 1 ATOM 639 C CB . ALA A 1 89 ? -1.167 -9.828 63.729 1.00 17.44 ? 89 ALA A CB 1 ATOM 640 N N . GLU A 1 90 ? -1.120 -7.071 61.789 1.00 17.00 ? 90 GLU A N 1 ATOM 641 C CA . GLU A 1 90 ? -1.315 -5.621 61.708 1.00 17.22 ? 90 GLU A CA 1 ATOM 642 C C . GLU A 1 90 ? -2.772 -5.337 61.391 1.00 17.56 ? 90 GLU A C 1 ATOM 643 O O . GLU A 1 90 ? -3.271 -5.825 60.388 1.00 16.13 ? 90 GLU A O 1 ATOM 644 C CB . GLU A 1 90 ? -0.456 -4.997 60.614 1.00 18.51 ? 90 GLU A CB 1 ATOM 645 C CG . GLU A 1 90 ? 1.038 -5.344 60.788 1.00 19.76 ? 90 GLU A CG 1 ATOM 646 C CD . GLU A 1 90 ? 1.915 -4.908 59.638 1.00 21.25 ? 90 GLU A CD 1 ATOM 647 O OE1 . GLU A 1 90 ? 1.446 -4.782 58.484 1.00 22.34 ? 90 GLU A OE1 1 ATOM 648 O OE2 . GLU A 1 90 ? 3.116 -4.664 59.905 1.00 27.06 ? 90 GLU A OE2 1 ATOM 649 N N . TYR A 1 91 ? -3.410 -4.531 62.228 1.00 16.90 ? 91 TYR A N 1 ATOM 650 C CA . TYR A 1 91 ? -4.828 -4.157 62.014 1.00 17.58 ? 91 TYR A CA 1 ATOM 651 C C . TYR A 1 91 ? -4.784 -2.965 61.094 1.00 16.12 ? 91 TYR A C 1 ATOM 652 O O . TYR A 1 91 ? -4.860 -1.818 61.534 1.00 16.84 ? 91 TYR A O 1 ATOM 653 C CB . TYR A 1 91 ? -5.479 -3.842 63.345 1.00 19.62 ? 91 TYR A CB 1 ATOM 654 C CG . TYR A 1 91 ? -5.566 -5.021 64.298 1.00 21.52 ? 91 TYR A CG 1 ATOM 655 C CD1 . TYR A 1 91 ? -6.340 -6.123 63.994 1.00 25.72 ? 91 TYR A CD1 1 ATOM 656 C CD2 . TYR A 1 91 ? -4.913 -5.007 65.532 1.00 25.72 ? 91 TYR A CD2 1 ATOM 657 C CE1 . TYR A 1 91 ? -6.439 -7.210 64.875 1.00 24.78 ? 91 TYR A CE1 1 ATOM 658 C CE2 . TYR A 1 91 ? -5.006 -6.104 66.442 1.00 27.48 ? 91 TYR A CE2 1 ATOM 659 C CZ . TYR A 1 91 ? -5.768 -7.199 66.095 1.00 25.84 ? 91 TYR A CZ 1 ATOM 660 O OH . TYR A 1 91 ? -5.903 -8.288 66.934 1.00 23.06 ? 91 TYR A OH 1 ATOM 661 N N . GLN A 1 92 ? -4.588 -3.220 59.806 1.00 15.37 ? 92 GLN A N 1 ATOM 662 C CA . GLN A 1 92 ? -4.206 -2.122 58.910 1.00 15.30 ? 92 GLN A CA 1 ATOM 663 C C . GLN A 1 92 ? -5.325 -1.138 58.660 1.00 14.87 ? 92 GLN A C 1 ATOM 664 O O . GLN A 1 92 ? -5.089 0.052 58.614 1.00 15.03 ? 92 GLN A O 1 ATOM 665 C CB . GLN A 1 92 ? -3.702 -2.625 57.587 1.00 15.18 ? 92 GLN A CB 1 ATOM 666 C CG . GLN A 1 92 ? -2.355 -3.396 57.731 1.00 15.76 ? 92 GLN A CG 1 ATOM 667 C CD . GLN A 1 92 ? -1.692 -3.647 56.394 1.00 18.67 ? 92 GLN A CD 1 ATOM 668 O OE1 . GLN A 1 92 ? -2.318 -3.591 55.334 1.00 16.81 ? 92 GLN A OE1 1 ATOM 669 N NE2 . GLN A 1 92 ? -0.406 -3.969 56.446 1.00 14.97 ? 92 GLN A NE2 1 ATOM 670 N N . THR A 1 93 ? -6.526 -1.649 58.474 1.00 14.69 ? 93 THR A N 1 ATOM 671 C CA . THR A 1 93 ? -7.682 -0.749 58.292 1.00 15.00 ? 93 THR A CA 1 ATOM 672 C C . THR A 1 93 ? -8.873 -1.425 58.941 1.00 15.25 ? 93 THR A C 1 ATOM 673 O O . THR A 1 93 ? -8.787 -2.573 59.371 1.00 13.18 ? 93 THR A O 1 ATOM 674 C CB . THR A 1 93 ? -8.027 -0.481 56.784 1.00 15.67 ? 93 THR A CB 1 ATOM 675 O OG1 . THR A 1 93 ? -8.736 -1.615 56.281 1.00 17.65 ? 93 THR A OG1 1 ATOM 676 C CG2 . THR A 1 93 ? -6.831 -0.161 55.884 1.00 17.29 ? 93 THR A CG2 1 ATOM 677 N N . SER A 1 94 ? -10.009 -0.734 59.018 1.00 15.49 ? 94 SER A N 1 ATOM 678 C CA . SER A 1 94 ? -11.216 -1.350 59.571 1.00 16.62 ? 94 SER A CA 1 ATOM 679 C C . SER A 1 94 ? -11.653 -2.593 58.790 1.00 16.27 ? 94 SER A C 1 ATOM 680 O O . SER A 1 94 ? -12.385 -3.442 59.332 1.00 16.44 ? 94 SER A O 1 ATOM 681 C CB . SER A 1 94 ? -12.400 -0.340 59.559 1.00 17.66 ? 94 SER A CB 1 ATOM 682 O OG . SER A 1 94 ? -12.035 0.883 60.147 1.00 23.58 ? 94 SER A OG 1 ATOM 683 N N . ASN A 1 95 ? -11.232 -2.694 57.521 1.00 14.48 ? 95 ASN A N 1 ATOM 684 C CA . ASN A 1 95 ? -11.656 -3.794 56.689 1.00 14.95 ? 95 ASN A CA 1 ATOM 685 C C . ASN A 1 95 ? -10.542 -4.663 56.145 1.00 14.72 ? 95 ASN A C 1 ATOM 686 O O . ASN A 1 95 ? -10.797 -5.492 55.309 1.00 15.47 ? 95 ASN A O 1 ATOM 687 C CB . ASN A 1 95 ? -12.435 -3.285 55.508 1.00 14.97 ? 95 ASN A CB 1 ATOM 688 C CG . ASN A 1 95 ? -13.764 -2.674 55.930 1.00 18.96 ? 95 ASN A CG 1 ATOM 689 O OD1 . ASN A 1 95 ? -14.794 -3.332 55.896 1.00 27.35 ? 95 ASN A OD1 1 ATOM 690 N ND2 . ASN A 1 95 ? -13.723 -1.442 56.365 1.00 19.09 ? 95 ASN A ND2 1 ATOM 691 N N . ARG A 1 96 ? -9.322 -4.457 56.606 1.00 13.73 ? 96 ARG A N 1 ATOM 692 C CA . ARG A 1 96 ? -8.217 -5.249 56.064 1.00 12.56 ? 96 ARG A CA 1 ATOM 693 C C . ARG A 1 96 ? -7.290 -5.621 57.211 1.00 13.58 ? 96 ARG A C 1 ATOM 694 O O . ARG A 1 96 ? -6.812 -4.744 57.964 1.00 14.27 ? 96 ARG A O 1 ATOM 695 C CB . ARG A 1 96 ? -7.477 -4.457 54.978 1.00 12.59 ? 96 ARG A CB 1 ATOM 696 C CG . ARG A 1 96 ? -6.216 -5.197 54.426 1.00 12.19 ? 96 ARG A CG 1 ATOM 697 C CD . ARG A 1 96 ? -5.564 -4.403 53.326 1.00 14.01 ? 96 ARG A CD 1 ATOM 698 N NE . ARG A 1 96 ? -4.662 -3.353 53.801 1.00 16.07 ? 96 ARG A NE 1 ATOM 699 C CZ . ARG A 1 96 ? -4.731 -2.071 53.466 1.00 18.48 ? 96 ARG A CZ 1 ATOM 700 N NH1 . ARG A 1 96 ? -5.702 -1.604 52.665 1.00 19.60 ? 96 ARG A NH1 1 ATOM 701 N NH2 . ARG A 1 96 ? -3.813 -1.231 53.927 1.00 19.27 ? 96 ARG A NH2 1 ATOM 702 N N . PHE A 1 97 ? -7.066 -6.928 57.336 1.00 13.09 ? 97 PHE A N 1 ATOM 703 C CA . PHE A 1 97 ? -6.182 -7.497 58.311 1.00 13.31 ? 97 PHE A CA 1 ATOM 704 C C . PHE A 1 97 ? -4.967 -8.046 57.537 1.00 13.47 ? 97 PHE A C 1 ATOM 705 O O . PHE A 1 97 ? -5.115 -8.625 56.455 1.00 12.73 ? 97 PHE A O 1 ATOM 706 C CB . PHE A 1 97 ? -6.897 -8.619 59.080 1.00 12.06 ? 97 PHE A CB 1 ATOM 707 C CG . PHE A 1 97 ? -6.042 -9.293 60.115 1.00 13.88 ? 97 PHE A CG 1 ATOM 708 C CD1 . PHE A 1 97 ? -5.467 -8.548 61.171 1.00 13.60 ? 97 PHE A CD1 1 ATOM 709 C CD2 . PHE A 1 97 ? -5.731 -10.637 60.001 1.00 13.49 ? 97 PHE A CD2 1 ATOM 710 C CE1 . PHE A 1 97 ? -4.631 -9.141 62.092 1.00 13.05 ? 97 PHE A CE1 1 ATOM 711 C CE2 . PHE A 1 97 ? -4.877 -11.265 60.963 1.00 14.48 ? 97 PHE A CE2 1 ATOM 712 C CZ . PHE A 1 97 ? -4.339 -10.533 61.982 1.00 11.89 ? 97 PHE A CZ 1 ATOM 713 N N . HIS A 1 98 ? -3.783 -7.910 58.118 1.00 15.26 ? 98 HIS A N 1 ATOM 714 C CA . HIS A 1 98 ? -2.576 -8.392 57.457 1.00 15.27 ? 98 HIS A CA 1 ATOM 715 C C . HIS A 1 98 ? -1.866 -9.241 58.505 1.00 15.36 ? 98 HIS A C 1 ATOM 716 O O . HIS A 1 98 ? -1.730 -8.797 59.637 1.00 14.38 ? 98 HIS A O 1 ATOM 717 C CB . HIS A 1 98 ? -1.732 -7.176 57.021 1.00 16.26 ? 98 HIS A CB 1 ATOM 718 C CG . HIS A 1 98 ? -0.347 -7.515 56.532 1.00 18.18 ? 98 HIS A CG 1 ATOM 719 N ND1 . HIS A 1 98 ? -0.093 -8.546 55.650 1.00 19.76 ? 98 HIS A ND1 1 ATOM 720 C CD2 . HIS A 1 98 ? 0.856 -6.929 56.776 1.00 19.61 ? 98 HIS A CD2 1 ATOM 721 C CE1 . HIS A 1 98 ? 1.209 -8.601 55.392 1.00 17.26 ? 98 HIS A CE1 1 ATOM 722 N NE2 . HIS A 1 98 ? 1.804 -7.621 56.049 1.00 20.46 ? 98 HIS A NE2 1 ATOM 723 N N . PHE A 1 99 ? -1.473 -10.476 58.168 1.00 15.69 ? 99 PHE A N 1 ATOM 724 C CA . PHE A 1 99 ? -0.587 -11.250 59.065 1.00 16.65 ? 99 PHE A CA 1 ATOM 725 C C . PHE A 1 99 ? 0.482 -11.961 58.235 1.00 17.61 ? 99 PHE A C 1 ATOM 726 O O . PHE A 1 99 ? 0.225 -12.372 57.099 1.00 16.72 ? 99 PHE A O 1 ATOM 727 C CB . PHE A 1 99 ? -1.334 -12.213 60.005 1.00 16.66 ? 99 PHE A CB 1 ATOM 728 C CG . PHE A 1 99 ? -1.952 -13.432 59.328 1.00 17.72 ? 99 PHE A CG 1 ATOM 729 C CD1 . PHE A 1 99 ? -1.283 -14.654 59.318 1.00 18.71 ? 99 PHE A CD1 1 ATOM 730 C CD2 . PHE A 1 99 ? -3.226 -13.370 58.764 1.00 18.39 ? 99 PHE A CD2 1 ATOM 731 C CE1 . PHE A 1 99 ? -1.851 -15.767 58.723 1.00 19.64 ? 99 PHE A CE1 1 ATOM 732 C CE2 . PHE A 1 99 ? -3.823 -14.520 58.168 1.00 18.74 ? 99 PHE A CE2 1 ATOM 733 C CZ . PHE A 1 99 ? -3.132 -15.709 58.163 1.00 17.16 ? 99 PHE A CZ 1 ATOM 734 N N . LYS A 1 100 ? 1.683 -12.047 58.794 1.00 17.81 ? 100 LYS A N 1 ATOM 735 C CA . LYS A 1 100 ? 2.768 -12.744 58.119 1.00 19.67 ? 100 LYS A CA 1 ATOM 736 C C . LYS A 1 100 ? 3.490 -13.674 59.067 1.00 19.01 ? 100 LYS A C 1 ATOM 737 O O . LYS A 1 100 ? 3.593 -13.425 60.269 1.00 19.66 ? 100 LYS A O 1 ATOM 738 C CB . LYS A 1 100 ? 3.726 -11.801 57.351 1.00 20.66 ? 100 LYS A CB 1 ATOM 739 C CG . LYS A 1 100 ? 4.406 -10.739 58.114 1.00 23.50 ? 100 LYS A CG 1 ATOM 740 C CD . LYS A 1 100 ? 5.286 -9.891 57.179 1.00 22.63 ? 100 LYS A CD 1 ATOM 741 C CE . LYS A 1 100 ? 6.169 -8.993 58.048 1.00 29.93 ? 100 LYS A CE 1 ATOM 742 N NZ . LYS A 1 100 ? 7.156 -8.251 57.210 1.00 32.64 ? 100 LYS A NZ 1 ATOM 743 N N . LEU A 1 101 ? 3.924 -14.799 58.510 1.00 19.16 ? 101 LEU A N 1 ATOM 744 C CA . LEU A 1 101 ? 4.661 -15.808 59.260 1.00 18.95 ? 101 LEU A CA 1 ATOM 745 C C . LEU A 1 101 ? 6.032 -15.818 58.621 1.00 18.83 ? 101 LEU A C 1 ATOM 746 O O . LEU A 1 101 ? 6.148 -16.027 57.406 1.00 18.24 ? 101 LEU A O 1 ATOM 747 C CB . LEU A 1 101 ? 3.989 -17.174 59.143 1.00 19.18 ? 101 LEU A CB 1 ATOM 748 C CG . LEU A 1 101 ? 2.597 -17.220 59.811 1.00 19.90 ? 101 LEU A CG 1 ATOM 749 C CD1 . LEU A 1 101 ? 1.699 -18.288 59.219 1.00 21.89 ? 101 LEU A CD1 1 ATOM 750 C CD2 . LEU A 1 101 ? 2.698 -17.374 61.340 1.00 22.27 ? 101 LEU A CD2 1 ATOM 751 N N . THR A 1 102 ? 7.047 -15.511 59.419 1.00 18.77 ? 102 THR A N 1 ATOM 752 C CA . THR A 1 102 ? 8.406 -15.392 58.904 1.00 20.18 ? 102 THR A CA 1 ATOM 753 C C . THR A 1 102 ? 9.307 -16.304 59.751 1.00 19.80 ? 102 THR A C 1 ATOM 754 O O . THR A 1 102 ? 8.885 -16.789 60.783 1.00 18.52 ? 102 THR A O 1 ATOM 755 C CB . THR A 1 102 ? 8.872 -13.896 58.918 1.00 21.03 ? 102 THR A CB 1 ATOM 756 O OG1 . THR A 1 102 ? 8.750 -13.341 60.235 1.00 20.67 ? 102 THR A OG1 1 ATOM 757 C CG2 . THR A 1 102 ? 8.009 -13.029 57.960 1.00 20.62 ? 102 THR A CG2 1 ATOM 758 N N . ASP A 1 103 ? 10.532 -16.559 59.311 1.00 20.88 ? 103 ASP A N 1 ATOM 759 C CA . ASP A 1 103 ? 11.507 -17.266 60.140 1.00 21.93 ? 103 ASP A CA 1 ATOM 760 C C . ASP A 1 103 ? 12.065 -16.240 61.137 1.00 23.05 ? 103 ASP A C 1 ATOM 761 O O . ASP A 1 103 ? 12.603 -15.220 60.744 1.00 22.99 ? 103 ASP A O 1 ATOM 762 C CB . ASP A 1 103 ? 12.623 -17.840 59.232 1.00 20.85 ? 103 ASP A CB 1 ATOM 763 C CG . ASP A 1 103 ? 13.676 -18.643 60.005 1.00 24.68 ? 103 ASP A CG 1 ATOM 764 O OD1 . ASP A 1 103 ? 13.763 -18.513 61.249 1.00 24.07 ? 103 ASP A OD1 1 ATOM 765 O OD2 . ASP A 1 103 ? 14.431 -19.404 59.340 1.00 25.69 ? 103 ASP A OD2 1 ATOM 766 N N . GLN A 1 104 ? 11.931 -16.510 62.427 1.00 25.54 ? 104 GLN A N 1 ATOM 767 C CA . GLN A 1 104 ? 12.315 -15.541 63.442 1.00 28.46 ? 104 GLN A CA 1 ATOM 768 C C . GLN A 1 104 ? 13.795 -15.169 63.363 1.00 29.90 ? 104 GLN A C 1 ATOM 769 O O . GLN A 1 104 ? 14.173 -14.032 63.654 1.00 30.67 ? 104 GLN A O 1 ATOM 770 C CB . GLN A 1 104 ? 11.965 -16.097 64.820 1.00 29.11 ? 104 GLN A CB 1 ATOM 771 C CG . GLN A 1 104 ? 11.456 -15.058 65.777 1.00 32.02 ? 104 GLN A CG 1 ATOM 772 C CD . GLN A 1 104 ? 11.530 -15.504 67.210 1.00 36.37 ? 104 GLN A CD 1 ATOM 773 O OE1 . GLN A 1 104 ? 11.395 -16.692 67.527 1.00 35.95 ? 104 GLN A OE1 1 ATOM 774 N NE2 . GLN A 1 104 ? 11.753 -14.544 68.099 1.00 40.55 ? 104 GLN A NE2 1 ATOM 775 N N . THR A 1 105 ? 14.633 -16.110 62.937 1.00 31.78 ? 105 THR A N 1 ATOM 776 C CA . THR A 1 105 ? 16.093 -15.861 62.929 1.00 33.77 ? 105 THR A CA 1 ATOM 777 C C . THR A 1 105 ? 16.779 -15.747 61.560 1.00 34.04 ? 105 THR A C 1 ATOM 778 O O . THR A 1 105 ? 18.007 -15.622 61.492 1.00 34.81 ? 105 THR A O 1 ATOM 779 C CB . THR A 1 105 ? 16.851 -16.875 63.818 1.00 34.11 ? 105 THR A CB 1 ATOM 780 O OG1 . THR A 1 105 ? 16.668 -18.199 63.309 1.00 36.46 ? 105 THR A OG1 1 ATOM 781 C CG2 . THR A 1 105 ? 16.344 -16.818 65.253 1.00 36.37 ? 105 THR A CG2 1 ATOM 782 N N . ASN A 1 106 ? 16.011 -15.768 60.469 1.00 33.10 ? 106 ASN A N 1 ATOM 783 C CA . ASN A 1 106 ? 16.586 -15.593 59.136 1.00 32.35 ? 106 ASN A CA 1 ATOM 784 C C . ASN A 1 106 ? 15.668 -14.795 58.221 1.00 31.01 ? 106 ASN A C 1 ATOM 785 O O . ASN A 1 106 ? 14.453 -15.015 58.212 1.00 29.27 ? 106 ASN A O 1 ATOM 786 C CB . ASN A 1 106 ? 16.884 -16.953 58.483 1.00 33.38 ? 106 ASN A CB 1 ATOM 787 C CG . ASN A 1 106 ? 17.837 -17.820 59.313 1.00 36.81 ? 106 ASN A CG 1 ATOM 788 O OD1 . ASN A 1 106 ? 17.457 -18.896 59.803 1.00 40.26 ? 106 ASN A OD1 1 ATOM 789 N ND2 . ASN A 1 106 ? 19.073 -17.357 59.475 1.00 37.69 ? 106 ASN A ND2 1 ATOM 790 N N . ASN A 1 107 ? 16.255 -13.868 57.471 1.00 29.42 ? 107 ASN A N 1 ATOM 791 C CA . ASN A 1 107 ? 15.549 -13.167 56.424 1.00 29.09 ? 107 ASN A CA 1 ATOM 792 C C . ASN A 1 107 ? 15.231 -14.171 55.314 1.00 27.35 ? 107 ASN A C 1 ATOM 793 O O . ASN A 1 107 ? 16.062 -15.016 54.978 1.00 27.00 ? 107 ASN A O 1 ATOM 794 C CB . ASN A 1 107 ? 16.383 -12.005 55.874 1.00 29.87 ? 107 ASN A CB 1 ATOM 795 C CG . ASN A 1 107 ? 16.548 -10.844 56.873 1.00 32.82 ? 107 ASN A CG 1 ATOM 796 O OD1 . ASN A 1 107 ? 17.605 -10.199 56.899 1.00 38.33 ? 107 ASN A OD1 1 ATOM 797 N ND2 . ASN A 1 107 ? 15.517 -10.558 57.674 1.00 34.69 ? 107 ASN A ND2 1 ATOM 798 N N . ARG A 1 108 ? 14.011 -14.113 54.789 1.00 23.69 ? 108 ARG A N 1 ATOM 799 C CA . ARG A 1 108 ? 13.593 -14.972 53.661 1.00 20.16 ? 108 ARG A CA 1 ATOM 800 C C . ARG A 1 108 ? 13.071 -14.091 52.537 1.00 19.09 ? 108 ARG A C 1 ATOM 801 O O . ARG A 1 108 ? 12.757 -12.922 52.759 1.00 18.08 ? 108 ARG A O 1 ATOM 802 C CB . ARG A 1 108 ? 12.497 -15.961 54.089 1.00 21.13 ? 108 ARG A CB 1 ATOM 803 C CG . ARG A 1 108 ? 12.934 -17.004 55.101 1.00 20.26 ? 108 ARG A CG 1 ATOM 804 C CD . ARG A 1 108 ? 11.767 -17.889 55.539 1.00 17.21 ? 108 ARG A CD 1 ATOM 805 N NE . ARG A 1 108 ? 11.198 -18.585 54.384 1.00 15.01 ? 108 ARG A NE 1 ATOM 806 C CZ . ARG A 1 108 ? 11.689 -19.688 53.853 1.00 18.99 ? 108 ARG A CZ 1 ATOM 807 N NH1 . ARG A 1 108 ? 12.756 -20.294 54.399 1.00 16.11 ? 108 ARG A NH1 1 ATOM 808 N NH2 . ARG A 1 108 ? 11.100 -20.215 52.789 1.00 15.46 ? 108 ARG A NH2 1 ATOM 809 N N . PHE A 1 109 ? 12.954 -14.664 51.340 1.00 17.37 ? 109 PHE A N 1 ATOM 810 C CA . PHE A 1 109 ? 12.525 -13.906 50.200 1.00 16.04 ? 109 PHE A CA 1 ATOM 811 C C . PHE A 1 109 ? 11.103 -13.382 50.452 1.00 16.54 ? 109 PHE A C 1 ATOM 812 O O . PHE A 1 109 ? 10.232 -14.158 50.809 1.00 14.84 ? 109 PHE A O 1 ATOM 813 C CB . PHE A 1 109 ? 12.496 -14.759 48.944 1.00 16.55 ? 109 PHE A CB 1 ATOM 814 C CG . PHE A 1 109 ? 11.912 -14.020 47.766 1.00 15.88 ? 109 PHE A CG 1 ATOM 815 C CD1 . PHE A 1 109 ? 12.670 -13.080 47.079 1.00 17.56 ? 109 PHE A CD1 1 ATOM 816 C CD2 . PHE A 1 109 ? 10.545 -14.177 47.431 1.00 17.37 ? 109 PHE A CD2 1 ATOM 817 C CE1 . PHE A 1 109 ? 12.106 -12.342 46.035 1.00 19.10 ? 109 PHE A CE1 1 ATOM 818 C CE2 . PHE A 1 109 ? 9.993 -13.453 46.392 1.00 15.48 ? 109 PHE A CE2 1 ATOM 819 C CZ . PHE A 1 109 ? 10.772 -12.533 45.698 1.00 15.33 ? 109 PHE A CZ 1 ATOM 820 N N . GLU A 1 110 ? 10.926 -12.085 50.268 1.00 16.44 ? 110 GLU A N 1 ATOM 821 C CA . GLU A 1 110 ? 9.602 -11.456 50.302 1.00 17.42 ? 110 GLU A CA 1 ATOM 822 C C . GLU A 1 110 ? 9.387 -10.738 48.990 1.00 17.43 ? 110 GLU A C 1 ATOM 823 O O . GLU A 1 110 ? 10.301 -10.082 48.468 1.00 17.59 ? 110 GLU A O 1 ATOM 824 C CB . GLU A 1 110 ? 9.525 -10.481 51.472 1.00 18.21 ? 110 GLU A CB 1 ATOM 825 C CG . GLU A 1 110 ? 9.838 -11.124 52.793 1.00 21.40 ? 110 GLU A CG 1 ATOM 826 C CD . GLU A 1 110 ? 9.395 -10.318 53.966 1.00 29.84 ? 110 GLU A CD 1 ATOM 827 O OE1 . GLU A 1 110 ? 8.308 -9.655 53.895 1.00 33.47 ? 110 GLU A OE1 1 ATOM 828 O OE2 . GLU A 1 110 ? 10.110 -10.402 54.987 1.00 28.45 ? 110 GLU A OE2 1 ATOM 829 N N . VAL A 1 111 ? 8.162 -10.809 48.454 1.00 16.95 ? 111 VAL A N 1 ATOM 830 C CA . VAL A 1 111 ? 7.874 -10.194 47.148 1.00 15.72 ? 111 VAL A CA 1 ATOM 831 C C . VAL A 1 111 ? 8.126 -8.703 47.155 1.00 15.99 ? 111 VAL A C 1 ATOM 832 O O . VAL A 1 111 ? 7.559 -7.978 47.979 1.00 16.43 ? 111 VAL A O 1 ATOM 833 C CB . VAL A 1 111 ? 6.409 -10.468 46.707 1.00 16.06 ? 111 VAL A CB 1 ATOM 834 C CG1 . VAL A 1 111 ? 6.077 -9.783 45.356 1.00 14.90 ? 111 VAL A CG1 1 ATOM 835 C CG2 . VAL A 1 111 ? 6.166 -11.983 46.674 1.00 15.93 ? 111 VAL A CG2 1 ATOM 836 N N . PRO A 1 112 ? 8.986 -8.214 46.244 1.00 15.92 ? 112 PRO A N 1 ATOM 837 C CA . PRO A 1 112 ? 9.274 -6.783 46.197 1.00 17.22 ? 112 PRO A CA 1 ATOM 838 C C . PRO A 1 112 ? 8.217 -6.007 45.396 1.00 17.06 ? 112 PRO A C 1 ATOM 839 O O . PRO A 1 112 ? 8.514 -5.408 44.363 1.00 18.03 ? 112 PRO A O 1 ATOM 840 C CB . PRO A 1 112 ? 10.616 -6.715 45.455 1.00 17.28 ? 112 PRO A CB 1 ATOM 841 C CG . PRO A 1 112 ? 10.694 -7.898 44.685 1.00 17.29 ? 112 PRO A CG 1 ATOM 842 C CD . PRO A 1 112 ? 9.802 -8.972 45.270 1.00 17.25 ? 112 PRO A CD 1 ATOM 843 N N . HIS A 1 113 ? 6.987 -6.027 45.871 1.00 17.28 ? 113 HIS A N 1 ATOM 844 C CA . HIS A 1 113 ? 5.884 -5.425 45.110 1.00 17.14 ? 113 HIS A CA 1 ATOM 845 C C . HIS A 1 113 ? 6.039 -3.912 44.872 1.00 17.77 ? 113 HIS A C 1 ATOM 846 O O . HIS A 1 113 ? 6.490 -3.179 45.751 1.00 18.34 ? 113 HIS A O 1 ATOM 847 C CB . HIS A 1 113 ? 4.574 -5.727 45.831 1.00 17.23 ? 113 HIS A CB 1 ATOM 848 C CG . HIS A 1 113 ? 3.393 -5.732 44.923 1.00 17.45 ? 113 HIS A CG 1 ATOM 849 N ND1 . HIS A 1 113 ? 2.540 -4.648 44.811 1.00 16.84 ? 113 HIS A ND1 1 ATOM 850 C CD2 . HIS A 1 113 ? 2.922 -6.676 44.075 1.00 18.08 ? 113 HIS A CD2 1 ATOM 851 C CE1 . HIS A 1 113 ? 1.607 -4.921 43.915 1.00 15.37 ? 113 HIS A CE1 1 ATOM 852 N NE2 . HIS A 1 113 ? 1.802 -6.150 43.466 1.00 13.93 ? 113 HIS A NE2 1 ATOM 853 N N . GLU A 1 114 ? 5.649 -3.446 43.688 1.00 18.45 ? 114 GLU A N 1 ATOM 854 C CA . GLU A 1 114 ? 5.832 -2.047 43.300 1.00 19.53 ? 114 GLU A CA 1 ATOM 855 C C . GLU A 1 114 ? 4.784 -1.156 43.977 1.00 19.76 ? 114 GLU A C 1 ATOM 856 O O . GLU A 1 114 ? 5.042 0.024 44.238 1.00 19.85 ? 114 GLU A O 1 ATOM 857 C CB . GLU A 1 114 ? 5.761 -1.923 41.765 1.00 21.25 ? 114 GLU A CB 1 ATOM 858 C CG . GLU A 1 114 ? 5.989 -0.531 41.145 1.00 22.40 ? 114 GLU A CG 1 ATOM 859 C CD . GLU A 1 114 ? 4.770 0.375 41.231 1.00 25.99 ? 114 GLU A CD 1 ATOM 860 O OE1 . GLU A 1 114 ? 3.595 -0.096 41.390 1.00 22.23 ? 114 GLU A OE1 1 ATOM 861 O OE2 . GLU A 1 114 ? 4.984 1.580 41.138 1.00 29.76 ? 114 GLU A OE2 1 ATOM 862 N N . HIS A 1 115 ? 3.611 -1.706 44.282 1.00 17.30 ? 115 HIS A N 1 ATOM 863 C CA . HIS A 1 115 ? 2.558 -0.844 44.819 1.00 17.39 ? 115 HIS A CA 1 ATOM 864 C C . HIS A 1 115 ? 2.440 -0.968 46.347 1.00 17.02 ? 115 HIS A C 1 ATOM 865 O O . HIS A 1 115 ? 2.407 0.048 47.051 1.00 17.02 ? 115 HIS A O 1 ATOM 866 C CB . HIS A 1 115 ? 1.219 -1.137 44.133 1.00 16.79 ? 115 HIS A CB 1 ATOM 867 C CG . HIS A 1 115 ? 0.139 -0.178 44.505 1.00 17.68 ? 115 HIS A CG 1 ATOM 868 N ND1 . HIS A 1 115 ? 0.011 1.055 43.913 1.00 20.25 ? 115 HIS A ND1 1 ATOM 869 C CD2 . HIS A 1 115 ? -0.855 -0.265 45.418 1.00 17.58 ? 115 HIS A CD2 1 ATOM 870 C CE1 . HIS A 1 115 ? -1.032 1.687 44.429 1.00 21.48 ? 115 HIS A CE1 1 ATOM 871 N NE2 . HIS A 1 115 ? -1.562 0.915 45.363 1.00 18.59 ? 115 HIS A NE2 1 ATOM 872 N N . VAL A 1 116 ? 2.350 -2.197 46.852 1.00 15.62 ? 116 VAL A N 1 ATOM 873 C CA . VAL A 1 116 ? 2.173 -2.465 48.264 1.00 17.91 ? 116 VAL A CA 1 ATOM 874 C C . VAL A 1 116 ? 3.384 -1.915 49.040 1.00 19.87 ? 116 VAL A C 1 ATOM 875 O O . VAL A 1 116 ? 4.519 -2.159 48.647 1.00 19.84 ? 116 VAL A O 1 ATOM 876 C CB . VAL A 1 116 ? 1.961 -3.971 48.523 1.00 17.85 ? 116 VAL A CB 1 ATOM 877 C CG1 . VAL A 1 116 ? 1.980 -4.326 50.001 1.00 17.06 ? 116 VAL A CG1 1 ATOM 878 C CG2 . VAL A 1 116 ? 0.601 -4.437 47.921 1.00 16.98 ? 116 VAL A CG2 1 ATOM 879 N N . GLN A 1 117 ? 3.141 -1.154 50.104 1.00 20.89 ? 117 GLN A N 1 ATOM 880 C CA . GLN A 1 117 ? 4.244 -0.687 50.959 1.00 24.60 ? 117 GLN A CA 1 ATOM 881 C C . GLN A 1 117 ? 4.190 -1.327 52.324 1.00 24.64 ? 117 GLN A C 1 ATOM 882 O O . GLN A 1 117 ? 3.157 -1.827 52.726 1.00 23.79 ? 117 GLN A O 1 ATOM 883 C CB . GLN A 1 117 ? 4.182 0.816 51.181 1.00 25.15 ? 117 GLN A CB 1 ATOM 884 C CG . GLN A 1 117 ? 4.210 1.668 49.974 1.00 30.26 ? 117 GLN A CG 1 ATOM 885 C CD . GLN A 1 117 ? 3.917 3.095 50.363 1.00 36.67 ? 117 GLN A CD 1 ATOM 886 O OE1 . GLN A 1 117 ? 2.777 3.438 50.709 1.00 41.42 ? 117 GLN A OE1 1 ATOM 887 N NE2 . GLN A 1 117 ? 4.944 3.930 50.364 1.00 37.75 ? 117 GLN A NE2 1 ATOM 888 N N . SER A 1 118 ? 5.302 -1.263 53.061 1.00 25.62 ? 118 SER A N 1 ATOM 889 C CA . SER A 1 118 ? 5.295 -1.706 54.453 1.00 26.97 ? 118 SER A CA 1 ATOM 890 C C . SER A 1 118 ? 4.403 -0.761 55.265 1.00 27.26 ? 118 SER A C 1 ATOM 891 O O . SER A 1 118 ? 4.295 0.437 54.972 1.00 26.98 ? 118 SER A O 1 ATOM 892 C CB . SER A 1 118 ? 6.720 -1.742 55.027 1.00 26.99 ? 118 SER A CB 1 ATOM 893 O OG . SER A 1 118 ? 7.250 -0.435 54.965 1.00 31.22 ? 118 SER A OG 1 ATOM 894 N N . PHE A 1 119 ? 3.721 -1.332 56.247 1.00 27.72 ? 119 PHE A N 1 ATOM 895 C CA . PHE A 1 119 ? 2.829 -0.589 57.120 1.00 28.89 ? 119 PHE A CA 1 ATOM 896 C C . PHE A 1 119 ? 3.654 0.046 58.211 1.00 30.20 ? 119 PHE A C 1 ATOM 897 O O . PHE A 1 119 ? 4.451 -0.613 58.864 1.00 29.29 ? 119 PHE A O 1 ATOM 898 C CB . PHE A 1 119 ? 1.825 -1.552 57.744 1.00 28.32 ? 119 PHE A CB 1 ATOM 899 C CG . PHE A 1 119 ? 0.750 -0.889 58.532 1.00 27.38 ? 119 PHE A CG 1 ATOM 900 C CD1 . PHE A 1 119 ? -0.193 -0.077 57.907 1.00 27.18 ? 119 PHE A CD1 1 ATOM 901 C CD2 . PHE A 1 119 ? 0.658 -1.085 59.891 1.00 26.13 ? 119 PHE A CD2 1 ATOM 902 C CE1 . PHE A 1 119 ? -1.213 0.534 58.643 1.00 23.55 ? 119 PHE A CE1 1 ATOM 903 C CE2 . PHE A 1 119 ? -0.363 -0.460 60.648 1.00 27.03 ? 119 PHE A CE2 1 ATOM 904 C CZ . PHE A 1 119 ? -1.292 0.353 60.010 1.00 26.54 ? 119 PHE A CZ 1 ATOM 905 N N . SER A 1 120 ? 3.475 1.347 58.368 1.00 32.02 ? 120 SER A N 1 ATOM 906 C CA . SER A 1 120 ? 3.918 2.066 59.552 1.00 33.97 ? 120 SER A CA 1 ATOM 907 C C . SER A 1 120 ? 2.622 2.708 59.958 1.00 34.23 ? 120 SER A C 1 ATOM 908 O O . SER A 1 120 ? 1.752 2.943 59.121 1.00 36.11 ? 120 SER A O 1 ATOM 909 C CB . SER A 1 120 ? 4.950 3.125 59.186 1.00 33.83 ? 120 SER A CB 1 ATOM 910 O OG . SER A 1 120 ? 4.398 4.013 58.230 1.00 37.40 ? 120 SER A OG 1 ATOM 911 N N . GLY A 1 121 ? 2.444 2.984 61.224 1.00 34.42 ? 121 GLY A N 1 ATOM 912 C CA . GLY A 1 121 ? 1.118 3.430 61.629 1.00 32.29 ? 121 GLY A CA 1 ATOM 913 C C . GLY A 1 121 ? 0.559 2.560 62.723 1.00 31.34 ? 121 GLY A C 1 ATOM 914 O O . GLY A 1 121 ? 1.201 1.598 63.180 1.00 29.76 ? 121 GLY A O 1 ATOM 915 N N . ASN A 1 122 ? -0.648 2.913 63.151 1.00 28.97 ? 122 ASN A N 1 ATOM 916 C CA . ASN A 1 122 ? -1.209 2.352 64.345 1.00 28.46 ? 122 ASN A CA 1 ATOM 917 C C . ASN A 1 122 ? -2.403 1.509 63.966 1.00 26.59 ? 122 ASN A C 1 ATOM 918 O O . ASN A 1 122 ? -3.011 1.780 62.943 1.00 26.34 ? 122 ASN A O 1 ATOM 919 C CB . ASN A 1 122 ? -1.633 3.489 65.282 1.00 29.33 ? 122 ASN A CB 1 ATOM 920 C CG . ASN A 1 122 ? -0.437 4.290 65.793 1.00 32.01 ? 122 ASN A CG 1 ATOM 921 O OD1 . ASN A 1 122 ? 0.601 3.724 66.121 1.00 32.55 ? 122 ASN A OD1 1 ATOM 922 N ND2 . ASN A 1 122 ? -0.578 5.599 65.839 1.00 32.60 ? 122 ASN A ND2 1 ATOM 923 N N . ALA A 1 123 ? -2.725 0.521 64.797 1.00 25.28 ? 123 ALA A N 1 ATOM 924 C CA . ALA A 1 123 ? -3.876 -0.354 64.584 1.00 24.11 ? 123 ALA A CA 1 ATOM 925 C C . ALA A 1 123 ? -5.097 0.526 64.278 1.00 24.37 ? 123 ALA A C 1 ATOM 926 O O . ALA A 1 123 ? -5.295 1.569 64.918 1.00 22.94 ? 123 ALA A O 1 ATOM 927 C CB . ALA A 1 123 ? -4.129 -1.193 65.821 1.00 24.64 ? 123 ALA A CB 1 ATOM 928 N N . ALA A 1 124 ? -5.904 0.124 63.310 1.00 23.68 ? 124 ALA A N 1 ATOM 929 C CA . ALA A 1 124 ? -7.075 0.907 62.950 1.00 23.12 ? 124 ALA A CA 1 ATOM 930 C C . ALA A 1 124 ? -8.108 0.859 64.068 1.00 23.83 ? 124 ALA A C 1 ATOM 931 O O . ALA A 1 124 ? -8.141 -0.098 64.833 1.00 24.13 ? 124 ALA A O 1 ATOM 932 C CB . ALA A 1 124 ? -7.686 0.406 61.658 1.00 22.82 ? 124 ALA A CB 1 ATOM 933 N N . ALA A 1 125 ? -8.922 1.911 64.138 1.00 24.13 ? 125 ALA A N 1 ATOM 934 C CA . ALA A 1 125 ? -10.110 1.990 65.005 1.00 25.31 ? 125 ALA A CA 1 ATOM 935 C C . ALA A 1 125 ? -11.297 1.337 64.300 1.00 25.59 ? 125 ALA A C 1 ATOM 936 O O . ALA A 1 125 ? -11.279 1.162 63.073 1.00 26.74 ? 125 ALA A O 1 ATOM 937 C CB . ALA A 1 125 ? -10.431 3.477 65.307 1.00 25.94 ? 125 ALA A CB 1 ATOM 938 N N . SER A 1 126 ? -12.332 0.985 65.060 1.00 26.10 ? 126 SER A N 1 ATOM 939 C CA . SER A 1 126 ? -13.622 0.519 64.504 1.00 25.89 ? 126 SER A CA 1 ATOM 940 C C . SER A 1 126 ? -13.501 -0.673 63.561 1.00 24.88 ? 126 SER A C 1 ATOM 941 O O . SER A 1 126 ? -14.083 -0.670 62.447 1.00 24.78 ? 126 SER A O 1 ATOM 942 C CB . SER A 1 126 ? -14.362 1.645 63.780 1.00 26.51 ? 126 SER A CB 1 ATOM 943 O OG . SER A 1 126 ? -14.570 2.762 64.627 1.00 30.06 ? 126 SER A OG 1 ATOM 944 N N . LEU A 1 127 ? -12.766 -1.698 63.992 1.00 22.84 ? 127 LEU A N 1 ATOM 945 C CA . LEU A 1 127 ? -12.558 -2.870 63.134 1.00 21.20 ? 127 LEU A CA 1 ATOM 946 C C . LEU A 1 127 ? -13.860 -3.568 62.833 1.00 21.14 ? 127 LEU A C 1 ATOM 947 O O . LEU A 1 127 ? -14.719 -3.678 63.715 1.00 21.00 ? 127 LEU A O 1 ATOM 948 C CB . LEU A 1 127 ? -11.632 -3.865 63.812 1.00 21.12 ? 127 LEU A CB 1 ATOM 949 C CG . LEU A 1 127 ? -10.266 -3.306 64.203 1.00 19.29 ? 127 LEU A CG 1 ATOM 950 C CD1 . LEU A 1 127 ? -9.483 -4.389 64.921 1.00 24.00 ? 127 LEU A CD1 1 ATOM 951 C CD2 . LEU A 1 127 ? -9.533 -2.837 62.977 1.00 18.13 ? 127 LEU A CD2 1 ATOM 952 N N . THR A 1 128 ? -14.011 -4.043 61.600 1.00 19.40 ? 128 THR A N 1 ATOM 953 C CA . THR A 1 128 ? -15.178 -4.859 61.252 1.00 19.90 ? 128 THR A CA 1 ATOM 954 C C . THR A 1 128 ? -14.923 -6.336 61.579 1.00 19.05 ? 128 THR A C 1 ATOM 955 O O . THR A 1 128 ? -15.814 -7.190 61.457 1.00 17.02 ? 128 THR A O 1 ATOM 956 C CB . THR A 1 128 ? -15.532 -4.726 59.764 1.00 20.84 ? 128 THR A CB 1 ATOM 957 O OG1 . THR A 1 128 ? -14.477 -5.281 58.989 1.00 22.06 ? 128 THR A OG1 1 ATOM 958 C CG2 . THR A 1 128 ? -15.690 -3.278 59.386 1.00 22.33 ? 128 THR A CG2 1 ATOM 959 N N . TYR A 1 129 ? -13.688 -6.628 61.992 1.00 17.00 ? 129 TYR A N 1 ATOM 960 C CA . TYR A 1 129 ? -13.283 -7.996 62.268 1.00 18.24 ? 129 TYR A CA 1 ATOM 961 C C . TYR A 1 129 ? -12.616 -8.146 63.667 1.00 18.18 ? 129 TYR A C 1 ATOM 962 O O . TYR A 1 129 ? -12.179 -7.151 64.270 1.00 17.58 ? 129 TYR A O 1 ATOM 963 C CB . TYR A 1 129 ? -12.342 -8.490 61.155 1.00 17.08 ? 129 TYR A CB 1 ATOM 964 C CG . TYR A 1 129 ? -11.081 -7.658 61.041 1.00 17.23 ? 129 TYR A CG 1 ATOM 965 C CD1 . TYR A 1 129 ? -9.953 -7.953 61.817 1.00 18.49 ? 129 TYR A CD1 1 ATOM 966 C CD2 . TYR A 1 129 ? -11.027 -6.569 60.178 1.00 16.69 ? 129 TYR A CD2 1 ATOM 967 C CE1 . TYR A 1 129 ? -8.808 -7.147 61.733 1.00 16.75 ? 129 TYR A CE1 1 ATOM 968 C CE2 . TYR A 1 129 ? -9.874 -5.771 60.072 1.00 13.88 ? 129 TYR A CE2 1 ATOM 969 C CZ . TYR A 1 129 ? -8.780 -6.086 60.849 1.00 15.76 ? 129 TYR A CZ 1 ATOM 970 O OH . TYR A 1 129 ? -7.674 -5.276 60.720 1.00 19.22 ? 129 TYR A OH 1 ATOM 971 N N . GLN A 1 130 ? -12.528 -9.390 64.141 1.00 18.20 ? 130 GLN A N 1 ATOM 972 C CA . GLN A 1 130 ? -11.779 -9.730 65.346 1.00 19.50 ? 130 GLN A CA 1 ATOM 973 C C . GLN A 1 130 ? -10.830 -10.871 65.008 1.00 18.67 ? 130 GLN A C 1 ATOM 974 O O . GLN A 1 130 ? -11.166 -11.748 64.233 1.00 19.36 ? 130 GLN A O 1 ATOM 975 C CB . GLN A 1 130 ? -12.703 -10.167 66.467 1.00 20.31 ? 130 GLN A CB 1 ATOM 976 C CG . GLN A 1 130 ? -12.070 -10.219 67.847 1.00 26.12 ? 130 GLN A CG 1 ATOM 977 C CD . GLN A 1 130 ? -13.098 -10.429 68.934 1.00 33.14 ? 130 GLN A CD 1 ATOM 978 O OE1 . GLN A 1 130 ? -14.308 -10.528 68.668 1.00 35.30 ? 130 GLN A OE1 1 ATOM 979 N NE2 . GLN A 1 130 ? -12.629 -10.500 70.173 1.00 34.83 ? 130 GLN A NE2 1 ATOM 980 N N . VAL A 1 131 ? -9.668 -10.847 65.622 1.00 17.99 ? 131 VAL A N 1 ATOM 981 C CA . VAL A 1 131 ? -8.644 -11.885 65.418 1.00 17.09 ? 131 VAL A CA 1 ATOM 982 C C . VAL A 1 131 ? -8.496 -12.643 66.723 1.00 17.65 ? 131 VAL A C 1 ATOM 983 O O . VAL A 1 131 ? -8.479 -12.037 67.810 1.00 16.94 ? 131 VAL A O 1 ATOM 984 C CB . VAL A 1 131 ? -7.325 -11.256 64.992 1.00 16.47 ? 131 VAL A CB 1 ATOM 985 C CG1 . VAL A 1 131 ? -6.216 -12.363 64.806 1.00 15.55 ? 131 VAL A CG1 1 ATOM 986 C CG2 . VAL A 1 131 ? -7.548 -10.440 63.696 1.00 18.19 ? 131 VAL A CG2 1 ATOM 987 N N . GLU A 1 132 ? -8.444 -13.969 66.631 1.00 17.87 ? 132 GLU A N 1 ATOM 988 C CA . GLU A 1 132 ? -8.281 -14.820 67.811 1.00 20.48 ? 132 GLU A CA 1 ATOM 989 C C . GLU A 1 132 ? -7.127 -15.782 67.553 1.00 19.93 ? 132 GLU A C 1 ATOM 990 O O . GLU A 1 132 ? -7.044 -16.368 66.485 1.00 19.77 ? 132 GLU A O 1 ATOM 991 C CB . GLU A 1 132 ? -9.590 -15.553 68.144 1.00 21.86 ? 132 GLU A CB 1 ATOM 992 C CG . GLU A 1 132 ? -9.448 -16.926 68.763 1.00 29.71 ? 132 GLU A CG 1 ATOM 993 C CD . GLU A 1 132 ? -9.294 -16.907 70.273 1.00 36.57 ? 132 GLU A CD 1 ATOM 994 O OE1 . GLU A 1 132 ? -9.017 -15.819 70.835 1.00 42.60 ? 132 GLU A OE1 1 ATOM 995 O OE2 . GLU A 1 132 ? -9.459 -17.990 70.896 1.00 39.30 ? 132 GLU A OE2 1 ATOM 996 N N . ILE A 1 133 ? -6.208 -15.879 68.505 1.00 18.83 ? 133 ILE A N 1 ATOM 997 C CA . ILE A 1 133 ? -5.015 -16.759 68.364 1.00 17.83 ? 133 ILE A CA 1 ATOM 998 C C . ILE A 1 133 ? -5.129 -17.855 69.401 1.00 18.21 ? 133 ILE A C 1 ATOM 999 O O . ILE A 1 133 ? -5.339 -17.559 70.585 1.00 18.00 ? 133 ILE A O 1 ATOM 1000 C CB . ILE A 1 133 ? -3.695 -15.956 68.613 1.00 19.16 ? 133 ILE A CB 1 ATOM 1001 C CG1 . ILE A 1 133 ? -3.576 -14.773 67.659 1.00 17.94 ? 133 ILE A CG1 1 ATOM 1002 C CG2 . ILE A 1 133 ? -2.427 -16.884 68.527 1.00 18.15 ? 133 ILE A CG2 1 ATOM 1003 C CD1 . ILE A 1 133 ? -3.528 -15.172 66.168 1.00 19.17 ? 133 ILE A CD1 1 ATOM 1004 N N . SER A 1 134 ? -5.039 -19.118 68.980 1.00 19.21 ? 134 SER A N 1 ATOM 1005 C CA . SER A 1 134 ? -4.924 -20.224 69.902 1.00 21.09 ? 134 SER A CA 1 ATOM 1006 C C . SER A 1 134 ? -3.467 -20.647 69.938 1.00 22.75 ? 134 SER A C 1 ATOM 1007 O O . SER A 1 134 ? -2.763 -20.549 68.936 1.00 21.99 ? 134 SER A O 1 ATOM 1008 C CB . SER A 1 134 ? -5.838 -21.381 69.483 1.00 21.75 ? 134 SER A CB 1 ATOM 1009 O OG . SER A 1 134 ? -7.192 -20.919 69.489 1.00 26.30 ? 134 SER A OG 1 ATOM 1010 N N . ARG A 1 135 ? -2.999 -21.086 71.095 1.00 24.12 ? 135 ARG A N 1 ATOM 1011 C CA . ARG A 1 135 ? -1.568 -21.291 71.227 1.00 26.32 ? 135 ARG A CA 1 ATOM 1012 C C . ARG A 1 135 ? -1.137 -22.752 71.199 1.00 26.18 ? 135 ARG A C 1 ATOM 1013 O O . ARG A 1 135 ? -0.009 -23.046 70.818 1.00 27.09 ? 135 ARG A O 1 ATOM 1014 C CB . ARG A 1 135 ? -1.049 -20.669 72.507 1.00 28.36 ? 135 ARG A CB 1 ATOM 1015 C CG . ARG A 1 135 ? -1.538 -19.266 72.883 1.00 32.33 ? 135 ARG A CG 1 ATOM 1016 C CD . ARG A 1 135 ? -1.615 -19.339 74.363 1.00 39.91 ? 135 ARG A CD 1 ATOM 1017 N NE . ARG A 1 135 ? -0.304 -19.687 74.875 1.00 43.37 ? 135 ARG A NE 1 ATOM 1018 C CZ . ARG A 1 135 ? 0.634 -18.780 75.127 1.00 44.96 ? 135 ARG A CZ 1 ATOM 1019 N NH1 . ARG A 1 135 ? 0.376 -17.466 74.937 1.00 42.97 ? 135 ARG A NH1 1 ATOM 1020 N NH2 . ARG A 1 135 ? 1.819 -19.190 75.567 1.00 45.17 ? 135 ARG A NH2 1 ATOM 1021 N N . GLN A 1 136 ? -2.000 -23.667 71.638 1.00 26.60 ? 136 GLN A N 1 ATOM 1022 C CA . GLN A 1 136 ? -1.568 -25.080 71.801 1.00 27.90 ? 136 GLN A CA 1 ATOM 1023 C C . GLN A 1 136 ? -2.556 -26.062 71.158 1.00 26.87 ? 136 GLN A C 1 ATOM 1024 O O . GLN A 1 136 ? -3.419 -26.589 71.838 1.00 29.18 ? 136 GLN A O 1 ATOM 1025 C CB . GLN A 1 136 ? -1.342 -25.440 73.284 1.00 27.92 ? 136 GLN A CB 1 ATOM 1026 C CG . GLN A 1 136 ? -0.789 -24.327 74.208 1.00 32.05 ? 136 GLN A CG 1 ATOM 1027 C CD . GLN A 1 136 ? 0.669 -23.955 73.950 1.00 38.30 ? 136 GLN A CD 1 ATOM 1028 O OE1 . GLN A 1 136 ? 1.510 -24.817 73.658 1.00 39.14 ? 136 GLN A OE1 1 ATOM 1029 N NE2 . GLN A 1 136 ? 0.979 -22.658 74.077 1.00 38.65 ? 136 GLN A NE2 1 ATOM 1030 N N . PRO A 1 137 ? -2.453 -26.305 69.842 1.00 25.98 ? 137 PRO A N 1 ATOM 1031 C CA . PRO A 1 137 ? -1.467 -25.851 68.873 1.00 24.58 ? 137 PRO A CA 1 ATOM 1032 C C . PRO A 1 137 ? -1.856 -24.495 68.283 1.00 23.75 ? 137 PRO A C 1 ATOM 1033 O O . PRO A 1 137 ? -2.978 -24.007 68.493 1.00 21.27 ? 137 PRO A O 1 ATOM 1034 C CB . PRO A 1 137 ? -1.522 -26.945 67.801 1.00 25.08 ? 137 PRO A CB 1 ATOM 1035 C CG . PRO A 1 137 ? -2.946 -27.434 67.851 1.00 25.48 ? 137 PRO A CG 1 ATOM 1036 C CD . PRO A 1 137 ? -3.498 -27.124 69.207 1.00 25.66 ? 137 PRO A CD 1 ATOM 1037 N N . PHE A 1 138 ? -0.922 -23.883 67.568 1.00 21.68 ? 138 PHE A N 1 ATOM 1038 C CA . PHE A 1 138 ? -1.183 -22.581 66.968 1.00 20.79 ? 138 PHE A CA 1 ATOM 1039 C C . PHE A 1 138 ? -2.331 -22.632 65.967 1.00 20.46 ? 138 PHE A C 1 ATOM 1040 O O . PHE A 1 138 ? -2.371 -23.491 65.078 1.00 19.85 ? 138 PHE A O 1 ATOM 1041 C CB . PHE A 1 138 ? 0.066 -22.053 66.251 1.00 20.43 ? 138 PHE A CB 1 ATOM 1042 C CG . PHE A 1 138 ? -0.207 -20.869 65.371 1.00 19.92 ? 138 PHE A CG 1 ATOM 1043 C CD1 . PHE A 1 138 ? -0.239 -21.003 63.982 1.00 19.14 ? 138 PHE A CD1 1 ATOM 1044 C CD2 . PHE A 1 138 ? -0.488 -19.634 65.928 1.00 21.09 ? 138 PHE A CD2 1 ATOM 1045 C CE1 . PHE A 1 138 ? -0.519 -19.920 63.175 1.00 19.08 ? 138 PHE A CE1 1 ATOM 1046 C CE2 . PHE A 1 138 ? -0.783 -18.545 65.106 1.00 20.92 ? 138 PHE A CE2 1 ATOM 1047 C CZ . PHE A 1 138 ? -0.769 -18.693 63.735 1.00 19.30 ? 138 PHE A CZ 1 ATOM 1048 N N . SER A 1 139 ? -3.261 -21.691 66.100 1.00 19.65 ? 139 SER A N 1 ATOM 1049 C CA . SER A 1 139 ? -4.131 -21.386 64.974 1.00 18.47 ? 139 SER A CA 1 ATOM 1050 C C . SER A 1 139 ? -4.502 -19.900 65.024 1.00 17.66 ? 139 SER A C 1 ATOM 1051 O O . SER A 1 139 ? -4.343 -19.236 66.064 1.00 17.96 ? 139 SER A O 1 ATOM 1052 C CB . SER A 1 139 ? -5.359 -22.291 64.948 1.00 19.19 ? 139 SER A CB 1 ATOM 1053 O OG . SER A 1 139 ? -6.185 -22.086 66.082 1.00 21.05 ? 139 SER A OG 1 ATOM 1054 N N . ILE A 1 140 ? -4.931 -19.373 63.885 1.00 15.68 ? 140 ILE A N 1 ATOM 1055 C CA . ILE A 1 140 ? -5.366 -17.983 63.785 1.00 16.31 ? 140 ILE A CA 1 ATOM 1056 C C . ILE A 1 140 ? -6.741 -17.964 63.158 1.00 16.02 ? 140 ILE A C 1 ATOM 1057 O O . ILE A 1 140 ? -6.986 -18.644 62.159 1.00 16.04 ? 140 ILE A O 1 ATOM 1058 C CB . ILE A 1 140 ? -4.389 -17.083 62.991 1.00 15.17 ? 140 ILE A CB 1 ATOM 1059 C CG1 . ILE A 1 140 ? -4.884 -15.610 62.952 1.00 15.92 ? 140 ILE A CG1 1 ATOM 1060 C CG2 . ILE A 1 140 ? -4.078 -17.656 61.568 1.00 15.84 ? 140 ILE A CG2 1 ATOM 1061 C CD1 . ILE A 1 140 ? -3.814 -14.540 62.441 1.00 17.04 ? 140 ILE A CD1 1 ATOM 1062 N N . LYS A 1 141 ? -7.614 -17.142 63.728 1.00 16.91 ? 141 LYS A N 1 ATOM 1063 C CA . LYS A 1 141 ? -9.005 -17.068 63.291 1.00 17.85 ? 141 LYS A CA 1 ATOM 1064 C C . LYS A 1 141 ? -9.342 -15.596 63.078 1.00 16.52 ? 141 LYS A C 1 ATOM 1065 O O . LYS A 1 141 ? -8.869 -14.724 63.808 1.00 17.02 ? 141 LYS A O 1 ATOM 1066 C CB . LYS A 1 141 ? -9.943 -17.652 64.382 1.00 18.17 ? 141 LYS A CB 1 ATOM 1067 C CG . LYS A 1 141 ? -11.318 -17.984 63.858 1.00 23.48 ? 141 LYS A CG 1 ATOM 1068 C CD . LYS A 1 141 ? -12.344 -18.332 64.956 1.00 23.36 ? 141 LYS A CD 1 ATOM 1069 C CE . LYS A 1 141 ? -12.017 -19.600 65.715 1.00 31.22 ? 141 LYS A CE 1 ATOM 1070 N NZ . LYS A 1 141 ? -12.910 -19.668 66.952 1.00 35.92 ? 141 LYS A NZ 1 ATOM 1071 N N . VAL A 1 142 ? -10.122 -15.307 62.046 1.00 15.54 ? 142 VAL A N 1 ATOM 1072 C CA . VAL A 1 142 ? -10.566 -13.952 61.832 1.00 15.13 ? 142 VAL A CA 1 ATOM 1073 C C . VAL A 1 142 ? -12.067 -14.104 61.706 1.00 15.04 ? 142 VAL A C 1 ATOM 1074 O O . VAL A 1 142 ? -12.547 -14.896 60.904 1.00 14.59 ? 142 VAL A O 1 ATOM 1075 C CB . VAL A 1 142 ? -9.989 -13.313 60.566 1.00 15.68 ? 142 VAL A CB 1 ATOM 1076 C CG1 . VAL A 1 142 ? -10.535 -11.884 60.382 1.00 15.12 ? 142 VAL A CG1 1 ATOM 1077 C CG2 . VAL A 1 142 ? -8.431 -13.248 60.629 1.00 15.83 ? 142 VAL A CG2 1 ATOM 1078 N N . THR A 1 143 ? -12.783 -13.362 62.534 1.00 16.20 ? 143 THR A N 1 ATOM 1079 C CA . THR A 1 143 ? -14.244 -13.426 62.548 1.00 16.94 ? 143 THR A CA 1 ATOM 1080 C C . THR A 1 143 ? -14.809 -12.057 62.230 1.00 16.95 ? 143 THR A C 1 ATOM 1081 O O . THR A 1 143 ? -14.174 -11.034 62.514 1.00 18.14 ? 143 THR A O 1 ATOM 1082 C CB . THR A 1 143 ? -14.761 -13.872 63.925 1.00 17.66 ? 143 THR A CB 1 ATOM 1083 O OG1 . THR A 1 143 ? -14.399 -12.877 64.906 1.00 23.80 ? 143 THR A OG1 1 ATOM 1084 C CG2 . THR A 1 143 ? -14.104 -15.179 64.318 1.00 15.26 ? 143 THR A CG2 1 ATOM 1085 N N . ARG A 1 144 ? -16.001 -12.058 61.648 1.00 16.48 ? 144 ARG A N 1 ATOM 1086 C CA . ARG A 1 144 ? -16.762 -10.835 61.361 1.00 17.13 ? 144 ARG A CA 1 ATOM 1087 C C . ARG A 1 144 ? -17.417 -10.423 62.686 1.00 17.08 ? 144 ARG A C 1 ATOM 1088 O O . ARG A 1 144 ? -18.093 -11.241 63.320 1.00 17.20 ? 144 ARG A O 1 ATOM 1089 C CB . ARG A 1 144 ? -17.863 -11.127 60.347 1.00 16.47 ? 144 ARG A CB 1 ATOM 1090 C CG . ARG A 1 144 ? -18.648 -9.887 59.972 1.00 14.77 ? 144 ARG A CG 1 ATOM 1091 C CD . ARG A 1 144 ? -19.611 -10.172 58.840 1.00 15.34 ? 144 ARG A CD 1 ATOM 1092 N NE . ARG A 1 144 ? -18.956 -10.329 57.539 1.00 16.61 ? 144 ARG A NE 1 ATOM 1093 C CZ . ARG A 1 144 ? -18.494 -9.326 56.785 1.00 14.62 ? 144 ARG A CZ 1 ATOM 1094 N NH1 . ARG A 1 144 ? -18.564 -8.069 57.182 1.00 17.93 ? 144 ARG A NH1 1 ATOM 1095 N NH2 . ARG A 1 144 ? -17.923 -9.590 55.625 1.00 17.57 ? 144 ARG A NH2 1 ATOM 1096 N N . ARG A 1 145 ? -17.202 -9.176 63.098 1.00 18.55 ? 145 ARG A N 1 ATOM 1097 C CA A ARG A 1 145 ? -17.651 -8.702 64.414 0.50 19.47 ? 145 ARG A CA 1 ATOM 1098 C CA B ARG A 1 145 ? -17.638 -8.716 64.422 0.50 19.59 ? 145 ARG A CA 1 ATOM 1099 C C . ARG A 1 145 ? -19.167 -8.706 64.528 1.00 20.13 ? 145 ARG A C 1 ATOM 1100 O O . ARG A 1 145 ? -19.732 -9.181 65.532 1.00 19.74 ? 145 ARG A O 1 ATOM 1101 C CB A ARG A 1 145 ? -17.127 -7.298 64.692 0.50 19.67 ? 145 ARG A CB 1 ATOM 1102 C CB B ARG A 1 145 ? -17.034 -7.341 64.751 0.50 19.52 ? 145 ARG A CB 1 ATOM 1103 C CG A ARG A 1 145 ? -15.807 -7.247 65.448 0.50 21.31 ? 145 ARG A CG 1 ATOM 1104 C CG B ARG A 1 145 ? -16.753 -7.112 66.249 0.50 20.52 ? 145 ARG A CG 1 ATOM 1105 C CD A ARG A 1 145 ? -15.392 -5.811 65.725 0.50 24.77 ? 145 ARG A CD 1 ATOM 1106 C CD B ARG A 1 145 ? -15.771 -5.954 66.553 0.50 20.82 ? 145 ARG A CD 1 ATOM 1107 N NE A ARG A 1 145 ? -16.314 -5.058 66.590 0.50 25.77 ? 145 ARG A NE 1 ATOM 1108 N NE B ARG A 1 145 ? -14.347 -6.220 66.299 0.50 21.29 ? 145 ARG A NE 1 ATOM 1109 C CZ A ARG A 1 145 ? -16.194 -3.762 66.862 0.50 26.11 ? 145 ARG A CZ 1 ATOM 1110 C CZ B ARG A 1 145 ? -13.426 -6.420 67.244 0.50 23.27 ? 145 ARG A CZ 1 ATOM 1111 N NH1 A ARG A 1 145 ? -15.201 -3.050 66.337 0.50 28.26 ? 145 ARG A NH1 1 ATOM 1112 N NH1 B ARG A 1 145 ? -13.772 -6.405 68.529 0.50 25.49 ? 145 ARG A NH1 1 ATOM 1113 N NH2 A ARG A 1 145 ? -17.066 -3.164 67.654 0.50 27.97 ? 145 ARG A NH2 1 ATOM 1114 N NH2 B ARG A 1 145 ? -12.159 -6.644 66.911 0.50 19.38 ? 145 ARG A NH2 1 ATOM 1115 N N . SER A 1 146 ? -19.821 -8.198 63.487 1.00 20.30 ? 146 SER A N 1 ATOM 1116 C CA . SER A 1 146 ? -21.290 -8.039 63.509 1.00 20.32 ? 146 SER A CA 1 ATOM 1117 C C . SER A 1 146 ? -22.084 -9.319 63.835 1.00 20.94 ? 146 SER A C 1 ATOM 1118 O O . SER A 1 146 ? -22.990 -9.309 64.694 1.00 21.59 ? 146 SER A O 1 ATOM 1119 C CB . SER A 1 146 ? -21.737 -7.400 62.194 1.00 20.21 ? 146 SER A CB 1 ATOM 1120 O OG . SER A 1 146 ? -21.711 -8.337 61.144 1.00 17.93 ? 146 SER A OG 1 ATOM 1121 N N . ASN A 1 147 ? -21.738 -10.434 63.193 1.00 20.52 ? 147 ASN A N 1 ATOM 1122 C CA . ASN A 1 147 ? -22.464 -11.694 63.363 1.00 20.34 ? 147 ASN A CA 1 ATOM 1123 C C . ASN A 1 147 ? -21.615 -12.855 63.899 1.00 20.54 ? 147 ASN A C 1 ATOM 1124 O O . ASN A 1 147 ? -22.107 -13.974 64.020 1.00 20.27 ? 147 ASN A O 1 ATOM 1125 C CB . ASN A 1 147 ? -23.185 -12.092 62.070 1.00 20.78 ? 147 ASN A CB 1 ATOM 1126 C CG . ASN A 1 147 ? -22.220 -12.334 60.907 1.00 22.15 ? 147 ASN A CG 1 ATOM 1127 O OD1 . ASN A 1 147 ? -20.981 -12.254 61.069 1.00 16.74 ? 147 ASN A OD1 1 ATOM 1128 N ND2 . ASN A 1 147 ? -22.778 -12.645 59.744 1.00 21.86 ? 147 ASN A ND2 1 ATOM 1129 N N . ASN A 1 148 ? -20.367 -12.557 64.275 1.00 19.43 ? 148 ASN A N 1 ATOM 1130 C CA . ASN A 1 148 ? -19.372 -13.554 64.719 1.00 20.64 ? 148 ASN A CA 1 ATOM 1131 C C . ASN A 1 148 ? -19.144 -14.702 63.726 1.00 19.69 ? 148 ASN A C 1 ATOM 1132 O O . ASN A 1 148 ? -18.752 -15.801 64.128 1.00 19.75 ? 148 ASN A O 1 ATOM 1133 C CB . ASN A 1 148 ? -19.627 -14.056 66.171 1.00 21.88 ? 148 ASN A CB 1 ATOM 1134 C CG . ASN A 1 148 ? -19.205 -13.033 67.254 1.00 22.59 ? 148 ASN A CG 1 ATOM 1135 O OD1 . ASN A 1 148 ? -19.612 -13.148 68.411 1.00 27.52 ? 148 ASN A OD1 1 ATOM 1136 N ND2 . ASN A 1 148 ? -18.395 -12.057 66.889 1.00 21.10 ? 148 ASN A ND2 1 ATOM 1137 N N . ARG A 1 149 ? -19.336 -14.435 62.432 1.00 17.91 ? 149 ARG A N 1 ATOM 1138 C CA . ARG A 1 149 ? -19.128 -15.485 61.407 1.00 17.79 ? 149 ARG A CA 1 ATOM 1139 C C . ARG A 1 149 ? -17.625 -15.720 61.324 1.00 17.06 ? 149 ARG A C 1 ATOM 1140 O O . ARG A 1 149 ? -16.871 -14.762 61.169 1.00 16.94 ? 149 ARG A O 1 ATOM 1141 C CB . ARG A 1 149 ? -19.640 -15.044 60.044 1.00 18.17 ? 149 ARG A CB 1 ATOM 1142 C CG . ARG A 1 149 ? -19.291 -15.975 58.885 1.00 21.91 ? 149 ARG A CG 1 ATOM 1143 C CD . ARG A 1 149 ? -20.426 -16.916 58.568 1.00 29.40 ? 149 ARG A CD 1 ATOM 1144 N NE . ARG A 1 149 ? -21.643 -16.172 58.226 1.00 32.25 ? 149 ARG A NE 1 ATOM 1145 C CZ . ARG A 1 149 ? -22.845 -16.726 58.124 1.00 37.26 ? 149 ARG A CZ 1 ATOM 1146 N NH1 . ARG A 1 149 ? -23.006 -18.039 58.335 1.00 37.80 ? 149 ARG A NH1 1 ATOM 1147 N NH2 . ARG A 1 149 ? -23.892 -15.967 57.819 1.00 37.44 ? 149 ARG A NH2 1 ATOM 1148 N N . VAL A 1 150 ? -17.207 -16.972 61.474 1.00 17.11 ? 150 VAL A N 1 ATOM 1149 C CA . VAL A 1 150 ? -15.777 -17.305 61.300 1.00 17.07 ? 150 VAL A CA 1 ATOM 1150 C C . VAL A 1 150 ? -15.461 -17.274 59.807 1.00 16.13 ? 150 VAL A C 1 ATOM 1151 O O . VAL A 1 150 ? -16.063 -18.013 59.003 1.00 16.11 ? 150 VAL A O 1 ATOM 1152 C CB . VAL A 1 150 ? -15.416 -18.677 61.910 1.00 18.13 ? 150 VAL A CB 1 ATOM 1153 C CG1 . VAL A 1 150 ? -13.953 -19.003 61.616 1.00 18.04 ? 150 VAL A CG1 1 ATOM 1154 C CG2 . VAL A 1 150 ? -15.661 -18.667 63.427 1.00 19.19 ? 150 VAL A CG2 1 ATOM 1155 N N . LEU A 1 151 ? -14.511 -16.415 59.432 1.00 14.42 ? 151 LEU A N 1 ATOM 1156 C CA . LEU A 1 151 ? -14.154 -16.218 58.035 1.00 14.33 ? 151 LEU A CA 1 ATOM 1157 C C . LEU A 1 151 ? -12.866 -16.988 57.682 1.00 16.24 ? 151 LEU A C 1 ATOM 1158 O O . LEU A 1 151 ? -12.835 -17.806 56.771 1.00 18.04 ? 151 LEU A O 1 ATOM 1159 C CB . LEU A 1 151 ? -13.931 -14.721 57.764 1.00 14.09 ? 151 LEU A CB 1 ATOM 1160 C CG . LEU A 1 151 ? -15.194 -13.851 58.065 1.00 13.93 ? 151 LEU A CG 1 ATOM 1161 C CD1 . LEU A 1 151 ? -14.909 -12.422 57.610 1.00 14.17 ? 151 LEU A CD1 1 ATOM 1162 C CD2 . LEU A 1 151 ? -16.347 -14.394 57.339 1.00 18.31 ? 151 LEU A CD2 1 ATOM 1163 N N . PHE A 1 152 ? -11.822 -16.694 58.432 1.00 16.37 ? 152 PHE A N 1 ATOM 1164 C CA . PHE A 1 152 ? -10.523 -17.391 58.288 1.00 17.62 ? 152 PHE A CA 1 ATOM 1165 C C . PHE A 1 152 ? -10.353 -18.201 59.569 1.00 17.19 ? 152 PHE A C 1 ATOM 1166 O O . PHE A 1 152 ? -10.606 -17.697 60.661 1.00 18.56 ? 152 PHE A O 1 ATOM 1167 C CB . PHE A 1 152 ? -9.444 -16.350 58.153 1.00 16.32 ? 152 PHE A CB 1 ATOM 1168 C CG . PHE A 1 152 ? -8.118 -16.895 57.649 1.00 19.00 ? 152 PHE A CG 1 ATOM 1169 C CD1 . PHE A 1 152 ? -7.757 -16.773 56.304 1.00 17.50 ? 152 PHE A CD1 1 ATOM 1170 C CD2 . PHE A 1 152 ? -7.255 -17.527 58.515 1.00 18.21 ? 152 PHE A CD2 1 ATOM 1171 C CE1 . PHE A 1 152 ? -6.503 -17.250 55.820 1.00 20.05 ? 152 PHE A CE1 1 ATOM 1172 C CE2 . PHE A 1 152 ? -6.004 -18.035 58.047 1.00 18.39 ? 152 PHE A CE2 1 ATOM 1173 C CZ . PHE A 1 152 ? -5.641 -17.899 56.710 1.00 18.79 ? 152 PHE A CZ 1 ATOM 1174 N N . ASP A 1 153 ? -10.015 -19.475 59.450 1.00 18.30 ? 153 ASP A N 1 ATOM 1175 C CA . ASP A 1 153 ? -9.752 -20.290 60.629 1.00 18.90 ? 153 ASP A CA 1 ATOM 1176 C C . ASP A 1 153 ? -8.754 -21.369 60.222 1.00 17.38 ? 153 ASP A C 1 ATOM 1177 O O . ASP A 1 153 ? -9.121 -22.328 59.543 1.00 17.02 ? 153 ASP A O 1 ATOM 1178 C CB . ASP A 1 153 ? -11.065 -20.947 61.112 1.00 19.14 ? 153 ASP A CB 1 ATOM 1179 C CG . ASP A 1 153 ? -10.868 -21.868 62.305 1.00 22.80 ? 153 ASP A CG 1 ATOM 1180 O OD1 . ASP A 1 153 ? -9.745 -21.969 62.873 1.00 22.79 ? 153 ASP A OD1 1 ATOM 1181 O OD2 . ASP A 1 153 ? -11.869 -22.515 62.688 1.00 27.16 ? 153 ASP A OD2 1 ATOM 1182 N N . SER A 1 154 ? -7.503 -21.199 60.627 1.00 18.27 ? 154 SER A N 1 ATOM 1183 C CA . SER A 1 154 ? -6.426 -22.140 60.272 1.00 17.80 ? 154 SER A CA 1 ATOM 1184 C C . SER A 1 154 ? -6.461 -23.448 61.099 1.00 18.87 ? 154 SER A C 1 ATOM 1185 O O . SER A 1 154 ? -5.697 -24.399 60.819 1.00 17.65 ? 154 SER A O 1 ATOM 1186 C CB . SER A 1 154 ? -5.062 -21.448 60.434 1.00 17.82 ? 154 SER A CB 1 ATOM 1187 O OG . SER A 1 154 ? -4.681 -21.409 61.818 1.00 18.64 ? 154 SER A OG 1 ATOM 1188 N N . SER A 1 155 ? -7.331 -23.519 62.124 1.00 18.99 ? 155 SER A N 1 ATOM 1189 C CA . SER A 1 155 ? -7.304 -24.661 63.044 1.00 19.48 ? 155 SER A CA 1 ATOM 1190 C C . SER A 1 155 ? -7.678 -26.013 62.406 1.00 18.89 ? 155 SER A C 1 ATOM 1191 O O . SER A 1 155 ? -7.491 -27.062 63.026 1.00 18.87 ? 155 SER A O 1 ATOM 1192 C CB . SER A 1 155 ? -8.194 -24.394 64.277 1.00 20.61 ? 155 SER A CB 1 ATOM 1193 O OG . SER A 1 155 ? -9.574 -24.408 63.894 1.00 21.83 ? 155 SER A OG 1 ATOM 1194 N N . ILE A 1 156 ? -8.189 -25.989 61.175 1.00 17.71 ? 156 ILE A N 1 ATOM 1195 C CA . ILE A 1 156 ? -8.519 -27.226 60.446 1.00 17.25 ? 156 ILE A CA 1 ATOM 1196 C C . ILE A 1 156 ? -7.264 -28.058 60.129 1.00 16.91 ? 156 ILE A C 1 ATOM 1197 O O . ILE A 1 156 ? -7.334 -29.264 59.998 1.00 17.15 ? 156 ILE A O 1 ATOM 1198 C CB . ILE A 1 156 ? -9.370 -26.934 59.167 1.00 17.15 ? 156 ILE A CB 1 ATOM 1199 C CG1 . ILE A 1 156 ? -10.003 -28.229 58.650 1.00 16.87 ? 156 ILE A CG1 1 ATOM 1200 C CG2 . ILE A 1 156 ? -8.620 -26.095 58.091 1.00 18.16 ? 156 ILE A CG2 1 ATOM 1201 C CD1 . ILE A 1 156 ? -10.925 -28.041 57.452 1.00 15.10 ? 156 ILE A CD1 1 ATOM 1202 N N . GLY A 1 157 ? -6.123 -27.395 60.032 1.00 16.71 ? 157 GLY A N 1 ATOM 1203 C CA . GLY A 1 157 ? -4.908 -28.073 59.640 1.00 17.16 ? 157 GLY A CA 1 ATOM 1204 C C . GLY A 1 157 ? -3.716 -27.465 60.348 1.00 16.97 ? 157 GLY A C 1 ATOM 1205 O O . GLY A 1 157 ? -3.831 -26.511 61.118 1.00 16.36 ? 157 GLY A O 1 ATOM 1206 N N . PRO A 1 158 ? -2.560 -28.053 60.119 1.00 17.02 ? 158 PRO A N 1 ATOM 1207 C CA . PRO A 1 158 ? -1.307 -27.575 60.676 1.00 17.45 ? 158 PRO A CA 1 ATOM 1208 C C . PRO A 1 158 ? -0.807 -26.325 59.985 1.00 16.99 ? 158 PRO A C 1 ATOM 1209 O O . PRO A 1 158 ? -1.217 -26.010 58.864 1.00 17.87 ? 158 PRO A O 1 ATOM 1210 C CB . PRO A 1 158 ? -0.355 -28.754 60.384 1.00 16.85 ? 158 PRO A CB 1 ATOM 1211 C CG . PRO A 1 158 ? -0.841 -29.289 59.098 1.00 17.02 ? 158 PRO A CG 1 ATOM 1212 C CD . PRO A 1 158 ? -2.373 -29.257 59.292 1.00 17.32 ? 158 PRO A CD 1 ATOM 1213 N N . LEU A 1 159 ? 0.064 -25.592 60.660 1.00 17.33 ? 159 LEU A N 1 ATOM 1214 C CA . LEU A 1 159 ? 0.982 -24.732 59.960 1.00 15.95 ? 159 LEU A CA 1 ATOM 1215 C C . LEU A 1 159 ? 2.213 -25.562 59.640 1.00 17.15 ? 159 LEU A C 1 ATOM 1216 O O . LEU A 1 159 ? 2.782 -26.171 60.557 1.00 16.07 ? 159 LEU A O 1 ATOM 1217 C CB . LEU A 1 159 ? 1.404 -23.552 60.841 1.00 16.53 ? 159 LEU A CB 1 ATOM 1218 C CG . LEU A 1 159 ? 2.654 -22.756 60.402 1.00 15.23 ? 159 LEU A CG 1 ATOM 1219 C CD1 . LEU A 1 159 ? 2.472 -22.091 59.006 1.00 15.23 ? 159 LEU A CD1 1 ATOM 1220 C CD2 . LEU A 1 159 ? 3.032 -21.701 61.468 1.00 15.83 ? 159 LEU A CD2 1 ATOM 1221 N N . LEU A 1 160 ? 2.648 -25.551 58.368 1.00 16.69 ? 160 LEU A N 1 ATOM 1222 C CA . LEU A 1 160 ? 3.898 -26.247 57.970 1.00 17.34 ? 160 LEU A CA 1 ATOM 1223 C C . LEU A 1 160 ? 4.828 -25.181 57.447 1.00 18.16 ? 160 LEU A C 1 ATOM 1224 O O . LEU A 1 160 ? 4.401 -24.318 56.685 1.00 17.31 ? 160 LEU A O 1 ATOM 1225 C CB . LEU A 1 160 ? 3.626 -27.343 56.927 1.00 16.92 ? 160 LEU A CB 1 ATOM 1226 C CG . LEU A 1 160 ? 2.578 -28.359 57.444 1.00 18.92 ? 160 LEU A CG 1 ATOM 1227 C CD1 . LEU A 1 160 ? 2.129 -29.288 56.348 1.00 23.31 ? 160 LEU A CD1 1 ATOM 1228 C CD2 . LEU A 1 160 ? 3.102 -29.156 58.623 1.00 22.09 ? 160 LEU A CD2 1 ATOM 1229 N N . PHE A 1 161 ? 6.089 -25.186 57.906 1.00 18.76 ? 161 PHE A N 1 ATOM 1230 C CA . PHE A 1 161 ? 7.008 -24.149 57.495 1.00 19.50 ? 161 PHE A CA 1 ATOM 1231 C C . PHE A 1 161 ? 8.432 -24.704 57.399 1.00 20.23 ? 161 PHE A C 1 ATOM 1232 O O . PHE A 1 161 ? 9.203 -24.589 58.355 1.00 21.19 ? 161 PHE A O 1 ATOM 1233 C CB . PHE A 1 161 ? 6.954 -22.993 58.506 1.00 20.13 ? 161 PHE A CB 1 ATOM 1234 C CG . PHE A 1 161 ? 7.445 -21.665 57.980 1.00 22.16 ? 161 PHE A CG 1 ATOM 1235 C CD1 . PHE A 1 161 ? 6.709 -20.504 58.227 1.00 26.98 ? 161 PHE A CD1 1 ATOM 1236 C CD2 . PHE A 1 161 ? 8.608 -21.567 57.227 1.00 25.55 ? 161 PHE A CD2 1 ATOM 1237 C CE1 . PHE A 1 161 ? 7.147 -19.271 57.742 1.00 27.46 ? 161 PHE A CE1 1 ATOM 1238 C CE2 . PHE A 1 161 ? 9.080 -20.343 56.757 1.00 26.00 ? 161 PHE A CE2 1 ATOM 1239 C CZ . PHE A 1 161 ? 8.360 -19.188 57.016 1.00 25.13 ? 161 PHE A CZ 1 ATOM 1240 N N . ALA A 1 162 ? 8.754 -25.309 56.263 1.00 20.49 ? 162 ALA A N 1 ATOM 1241 C CA . ALA A 1 162 ? 10.146 -25.662 55.934 1.00 20.55 ? 162 ALA A CA 1 ATOM 1242 C C . ALA A 1 162 ? 10.673 -24.710 54.872 1.00 20.66 ? 162 ALA A C 1 ATOM 1243 O O . ALA A 1 162 ? 9.910 -23.962 54.267 1.00 20.98 ? 162 ALA A O 1 ATOM 1244 C CB . ALA A 1 162 ? 10.208 -27.078 55.465 1.00 20.32 ? 162 ALA A CB 1 ATOM 1245 N N . ASP A 1 163 ? 11.980 -24.725 54.616 1.00 19.93 ? 163 ASP A N 1 ATOM 1246 C CA . ASP A 1 163 ? 12.548 -23.785 53.686 1.00 19.91 ? 163 ASP A CA 1 ATOM 1247 C C . ASP A 1 163 ? 11.849 -23.852 52.323 1.00 18.70 ? 163 ASP A C 1 ATOM 1248 O O . ASP A 1 163 ? 11.616 -22.817 51.689 1.00 18.83 ? 163 ASP A O 1 ATOM 1249 C CB . ASP A 1 163 ? 14.042 -24.098 53.536 1.00 21.45 ? 163 ASP A CB 1 ATOM 1250 C CG . ASP A 1 163 ? 14.806 -23.049 52.747 1.00 24.82 ? 163 ASP A CG 1 ATOM 1251 O OD1 . ASP A 1 163 ? 14.584 -21.818 52.884 1.00 27.99 ? 163 ASP A OD1 1 ATOM 1252 O OD2 . ASP A 1 163 ? 15.708 -23.474 52.001 1.00 28.59 ? 163 ASP A OD2 1 ATOM 1253 N N . GLN A 1 164 ? 11.506 -25.066 51.874 1.00 17.13 ? 164 GLN A N 1 ATOM 1254 C CA . GLN A 1 164 ? 10.885 -25.202 50.550 1.00 17.20 ? 164 GLN A CA 1 ATOM 1255 C C . GLN A 1 164 ? 9.540 -25.862 50.600 1.00 16.15 ? 164 GLN A C 1 ATOM 1256 O O . GLN A 1 164 ? 9.123 -26.506 49.638 1.00 16.81 ? 164 GLN A O 1 ATOM 1257 C CB . GLN A 1 164 ? 11.809 -25.956 49.589 1.00 17.81 ? 164 GLN A CB 1 ATOM 1258 C CG . GLN A 1 164 ? 13.114 -25.240 49.397 1.00 17.67 ? 164 GLN A CG 1 ATOM 1259 C CD . GLN A 1 164 ? 13.969 -25.920 48.350 1.00 17.56 ? 164 GLN A CD 1 ATOM 1260 O OE1 . GLN A 1 164 ? 13.720 -25.820 47.131 1.00 19.68 ? 164 GLN A OE1 1 ATOM 1261 N NE2 . GLN A 1 164 ? 14.916 -26.694 48.816 1.00 18.39 ? 164 GLN A NE2 1 ATOM 1262 N N . PHE A 1 165 ? 8.842 -25.713 51.727 1.00 16.49 ? 165 PHE A N 1 ATOM 1263 C CA . PHE A 1 165 ? 7.461 -26.230 51.837 1.00 16.38 ? 165 PHE A CA 1 ATOM 1264 C C . PHE A 1 165 ? 6.745 -25.473 52.954 1.00 16.30 ? 165 PHE A C 1 ATOM 1265 O O . PHE A 1 165 ? 7.048 -25.650 54.144 1.00 16.73 ? 165 PHE A O 1 ATOM 1266 C CB . PHE A 1 165 ? 7.403 -27.752 52.074 1.00 16.71 ? 165 PHE A CB 1 ATOM 1267 C CG . PHE A 1 165 ? 6.006 -28.349 51.936 1.00 18.21 ? 165 PHE A CG 1 ATOM 1268 C CD1 . PHE A 1 165 ? 5.538 -28.795 50.705 1.00 18.30 ? 165 PHE A CD1 1 ATOM 1269 C CD2 . PHE A 1 165 ? 5.187 -28.468 53.042 1.00 20.46 ? 165 PHE A CD2 1 ATOM 1270 C CE1 . PHE A 1 165 ? 4.245 -29.373 50.595 1.00 22.15 ? 165 PHE A CE1 1 ATOM 1271 C CE2 . PHE A 1 165 ? 3.894 -29.026 52.939 1.00 20.54 ? 165 PHE A CE2 1 ATOM 1272 C CZ . PHE A 1 165 ? 3.438 -29.479 51.732 1.00 18.87 ? 165 PHE A CZ 1 ATOM 1273 N N . LEU A 1 166 ? 5.785 -24.623 52.566 1.00 15.52 ? 166 LEU A N 1 ATOM 1274 C CA . LEU A 1 166 ? 5.032 -23.817 53.540 1.00 15.14 ? 166 LEU A CA 1 ATOM 1275 C C . LEU A 1 166 ? 3.560 -24.084 53.260 1.00 14.67 ? 166 LEU A C 1 ATOM 1276 O O . LEU A 1 166 ? 3.177 -24.120 52.108 1.00 14.51 ? 166 LEU A O 1 ATOM 1277 C CB . LEU A 1 166 ? 5.351 -22.333 53.386 1.00 14.20 ? 166 LEU A CB 1 ATOM 1278 C CG . LEU A 1 166 ? 6.778 -21.832 53.648 1.00 17.28 ? 166 LEU A CG 1 ATOM 1279 C CD1 . LEU A 1 166 ? 7.594 -22.013 52.406 1.00 16.93 ? 166 LEU A CD1 1 ATOM 1280 C CD2 . LEU A 1 166 ? 6.722 -20.362 54.019 1.00 14.90 ? 166 LEU A CD2 1 ATOM 1281 N N . GLN A 1 167 ? 2.772 -24.372 54.290 1.00 15.02 ? 167 GLN A N 1 ATOM 1282 C CA . GLN A 1 167 ? 1.357 -24.661 54.075 1.00 14.08 ? 167 GLN A CA 1 ATOM 1283 C C . GLN A 1 167 ? 0.530 -24.088 55.216 1.00 14.15 ? 167 GLN A C 1 ATOM 1284 O O . GLN A 1 167 ? 0.885 -24.222 56.397 1.00 13.27 ? 167 GLN A O 1 ATOM 1285 C CB . GLN A 1 167 ? 1.098 -26.183 53.985 1.00 15.15 ? 167 GLN A CB 1 ATOM 1286 C CG . GLN A 1 167 ? -0.394 -26.587 53.845 1.00 15.17 ? 167 GLN A CG 1 ATOM 1287 C CD . GLN A 1 167 ? -0.563 -28.086 53.694 1.00 14.86 ? 167 GLN A CD 1 ATOM 1288 O OE1 . GLN A 1 167 ? -1.293 -28.735 54.476 1.00 18.86 ? 167 GLN A OE1 1 ATOM 1289 N NE2 . GLN A 1 167 ? 0.120 -28.651 52.733 1.00 13.96 ? 167 GLN A NE2 1 ATOM 1290 N N . LEU A 1 168 ? -0.593 -23.464 54.864 1.00 14.03 ? 168 LEU A N 1 ATOM 1291 C CA . LEU A 1 168 ? -1.606 -23.110 55.871 1.00 15.23 ? 168 LEU A CA 1 ATOM 1292 C C . LEU A 1 168 ? -2.968 -23.318 55.227 1.00 15.37 ? 168 LEU A C 1 ATOM 1293 O O . LEU A 1 168 ? -3.104 -23.083 54.030 1.00 14.80 ? 168 LEU A O 1 ATOM 1294 C CB . LEU A 1 168 ? -1.463 -21.625 56.281 1.00 15.92 ? 168 LEU A CB 1 ATOM 1295 C CG . LEU A 1 168 ? -2.184 -21.148 57.576 1.00 14.86 ? 168 LEU A CG 1 ATOM 1296 C CD1 . LEU A 1 168 ? -1.724 -21.851 58.871 1.00 18.25 ? 168 LEU A CD1 1 ATOM 1297 C CD2 . LEU A 1 168 ? -2.055 -19.621 57.696 1.00 16.36 ? 168 LEU A CD2 1 ATOM 1298 N N . SER A 1 169 ? -3.953 -23.750 56.017 1.00 16.08 ? 169 SER A N 1 ATOM 1299 C CA . SER A 1 169 ? -5.295 -23.991 55.531 1.00 17.10 ? 169 SER A CA 1 ATOM 1300 C C . SER A 1 169 ? -6.246 -23.018 56.193 1.00 17.20 ? 169 SER A C 1 ATOM 1301 O O . SER A 1 169 ? -5.928 -22.450 57.199 1.00 18.24 ? 169 SER A O 1 ATOM 1302 C CB . SER A 1 169 ? -5.773 -25.386 55.924 1.00 16.50 ? 169 SER A CB 1 ATOM 1303 O OG . SER A 1 169 ? -4.892 -26.383 55.487 1.00 19.18 ? 169 SER A OG 1 ATOM 1304 N N . THR A 1 170 ? -7.427 -22.856 55.618 1.00 17.67 ? 170 THR A N 1 ATOM 1305 C CA . THR A 1 170 ? -8.489 -22.132 56.312 1.00 17.40 ? 170 THR A CA 1 ATOM 1306 C C . THR A 1 170 ? -9.850 -22.775 56.038 1.00 17.30 ? 170 THR A C 1 ATOM 1307 O O . THR A 1 170 ? -10.169 -23.112 54.887 1.00 16.51 ? 170 THR A O 1 ATOM 1308 C CB . THR A 1 170 ? -8.514 -20.651 55.941 1.00 18.03 ? 170 THR A CB 1 ATOM 1309 O OG1 . THR A 1 170 ? -9.609 -20.006 56.633 1.00 18.77 ? 170 THR A OG1 1 ATOM 1310 C CG2 . THR A 1 170 ? -8.654 -20.440 54.413 1.00 18.02 ? 170 THR A CG2 1 ATOM 1311 N N . ARG A 1 171 ? -10.641 -22.950 57.083 1.00 16.72 ? 171 ARG A N 1 ATOM 1312 C CA . ARG A 1 171 ? -12.069 -23.216 56.872 1.00 17.25 ? 171 ARG A CA 1 ATOM 1313 C C . ARG A 1 171 ? -12.662 -22.030 56.128 1.00 16.54 ? 171 ARG A C 1 ATOM 1314 O O . ARG A 1 171 ? -12.130 -20.900 56.186 1.00 17.78 ? 171 ARG A O 1 ATOM 1315 C CB . ARG A 1 171 ? -12.810 -23.380 58.200 1.00 16.57 ? 171 ARG A CB 1 ATOM 1316 C CG . ARG A 1 171 ? -12.325 -24.485 59.079 1.00 19.23 ? 171 ARG A CG 1 ATOM 1317 C CD . ARG A 1 171 ? -13.128 -24.546 60.363 1.00 24.06 ? 171 ARG A CD 1 ATOM 1318 N NE . ARG A 1 171 ? -12.241 -24.943 61.467 1.00 27.63 ? 171 ARG A NE 1 ATOM 1319 C CZ . ARG A 1 171 ? -12.042 -26.195 61.826 1.00 27.70 ? 171 ARG A CZ 1 ATOM 1320 N NH1 . ARG A 1 171 ? -12.679 -27.171 61.202 1.00 30.62 ? 171 ARG A NH1 1 ATOM 1321 N NH2 . ARG A 1 171 ? -11.220 -26.467 62.824 1.00 31.91 ? 171 ARG A NH2 1 ATOM 1322 N N . LEU A 1 172 ? -13.791 -22.272 55.483 1.00 16.28 ? 172 LEU A N 1 ATOM 1323 C CA . LEU A 1 172 ? -14.524 -21.219 54.803 1.00 15.58 ? 172 LEU A CA 1 ATOM 1324 C C . LEU A 1 172 ? -15.957 -21.264 55.253 1.00 15.83 ? 172 LEU A C 1 ATOM 1325 O O . LEU A 1 172 ? -16.443 -22.317 55.630 1.00 14.64 ? 172 LEU A O 1 ATOM 1326 C CB . LEU A 1 172 ? -14.420 -21.371 53.278 1.00 16.09 ? 172 LEU A CB 1 ATOM 1327 C CG . LEU A 1 172 ? -12.995 -21.217 52.689 1.00 17.37 ? 172 LEU A CG 1 ATOM 1328 C CD1 . LEU A 1 172 ? -13.014 -21.649 51.230 1.00 21.29 ? 172 LEU A CD1 1 ATOM 1329 C CD2 . LEU A 1 172 ? -12.476 -19.800 52.835 1.00 16.06 ? 172 LEU A CD2 1 ATOM 1330 N N . PRO A 1 173 ? -16.622 -20.102 55.277 1.00 17.17 ? 173 PRO A N 1 ATOM 1331 C CA . PRO A 1 173 ? -18.003 -20.067 55.748 1.00 18.17 ? 173 PRO A CA 1 ATOM 1332 C C . PRO A 1 173 ? -19.056 -20.510 54.743 1.00 19.68 ? 173 PRO A C 1 ATOM 1333 O O . PRO A 1 173 ? -20.230 -20.682 55.141 1.00 19.71 ? 173 PRO A O 1 ATOM 1334 C CB . PRO A 1 173 ? -18.194 -18.589 56.144 1.00 18.33 ? 173 PRO A CB 1 ATOM 1335 C CG . PRO A 1 173 ? -17.326 -17.824 55.202 1.00 17.08 ? 173 PRO A CG 1 ATOM 1336 C CD . PRO A 1 173 ? -16.099 -18.754 54.965 1.00 17.21 ? 173 PRO A CD 1 ATOM 1337 N N . SER A 1 174 ? -18.676 -20.666 53.467 1.00 18.56 ? 174 SER A N 1 ATOM 1338 C CA . SER A 1 174 ? -19.575 -21.118 52.440 1.00 20.48 ? 174 SER A CA 1 ATOM 1339 C C . SER A 1 174 ? -18.788 -21.708 51.275 1.00 20.47 ? 174 SER A C 1 ATOM 1340 O O . SER A 1 174 ? -17.544 -21.660 51.240 1.00 21.46 ? 174 SER A O 1 ATOM 1341 C CB . SER A 1 174 ? -20.467 -19.954 51.928 1.00 19.77 ? 174 SER A CB 1 ATOM 1342 O OG . SER A 1 174 ? -19.724 -19.155 51.028 1.00 19.46 ? 174 SER A OG 1 ATOM 1343 N N . THR A 1 175 ? -19.531 -22.268 50.336 1.00 19.28 ? 175 THR A N 1 ATOM 1344 C CA . THR A 1 175 ? -18.967 -22.781 49.113 1.00 20.20 ? 175 THR A CA 1 ATOM 1345 C C . THR A 1 175 ? -19.028 -21.780 47.954 1.00 19.35 ? 175 THR A C 1 ATOM 1346 O O . THR A 1 175 ? -18.662 -22.130 46.824 1.00 20.27 ? 175 THR A O 1 ATOM 1347 C CB . THR A 1 175 ? -19.665 -24.123 48.706 1.00 21.36 ? 175 THR A CB 1 ATOM 1348 O OG1 . THR A 1 175 ? -21.070 -23.891 48.590 1.00 22.70 ? 175 THR A OG1 1 ATOM 1349 C CG2 . THR A 1 175 ? -19.434 -25.187 49.781 1.00 22.38 ? 175 THR A CG2 1 ATOM 1350 N N . ASN A 1 176 ? -19.462 -20.539 48.213 1.00 16.98 ? 176 ASN A N 1 ATOM 1351 C CA . ASN A 1 176 ? -19.501 -19.537 47.149 1.00 15.59 ? 176 ASN A CA 1 ATOM 1352 C C . ASN A 1 176 ? -18.125 -18.914 47.080 1.00 14.90 ? 176 ASN A C 1 ATOM 1353 O O . ASN A 1 176 ? -17.886 -17.910 47.708 1.00 13.69 ? 176 ASN A O 1 ATOM 1354 C CB . ASN A 1 176 ? -20.512 -18.448 47.476 1.00 14.92 ? 176 ASN A CB 1 ATOM 1355 C CG . ASN A 1 176 ? -21.868 -19.014 47.760 1.00 18.66 ? 176 ASN A CG 1 ATOM 1356 O OD1 . ASN A 1 176 ? -22.302 -19.942 47.076 1.00 19.09 ? 176 ASN A OD1 1 ATOM 1357 N ND2 . ASN A 1 176 ? -22.536 -18.493 48.787 1.00 19.37 ? 176 ASN A ND2 1 ATOM 1358 N N . VAL A 1 177 ? -17.233 -19.540 46.332 1.00 14.88 ? 177 VAL A N 1 ATOM 1359 C CA . VAL A 1 177 ? -15.801 -19.187 46.332 1.00 13.99 ? 177 VAL A CA 1 ATOM 1360 C C . VAL A 1 177 ? -15.395 -18.883 44.879 1.00 13.80 ? 177 VAL A C 1 ATOM 1361 O O . VAL A 1 177 ? -15.721 -19.662 43.983 1.00 13.56 ? 177 VAL A O 1 ATOM 1362 C CB . VAL A 1 177 ? -14.995 -20.350 46.875 1.00 15.23 ? 177 VAL A CB 1 ATOM 1363 C CG1 . VAL A 1 177 ? -13.485 -20.081 46.638 1.00 14.40 ? 177 VAL A CG1 1 ATOM 1364 C CG2 . VAL A 1 177 ? -15.312 -20.544 48.384 1.00 18.02 ? 177 VAL A CG2 1 ATOM 1365 N N . TYR A 1 178 ? -14.738 -17.735 44.631 1.00 12.77 ? 178 TYR A N 1 ATOM 1366 C CA . TYR A 1 178 ? -14.512 -17.273 43.250 1.00 12.27 ? 178 TYR A CA 1 ATOM 1367 C C . TYR A 1 178 ? -13.097 -16.727 43.188 1.00 12.49 ? 178 TYR A C 1 ATOM 1368 O O . TYR A 1 178 ? -12.697 -16.016 44.085 1.00 13.32 ? 178 TYR A O 1 ATOM 1369 C CB . TYR A 1 178 ? -15.457 -16.091 42.885 1.00 11.81 ? 178 TYR A CB 1 ATOM 1370 C CG . TYR A 1 178 ? -16.884 -16.424 43.196 1.00 11.09 ? 178 TYR A CG 1 ATOM 1371 C CD1 . TYR A 1 178 ? -17.668 -17.096 42.283 1.00 11.41 ? 178 TYR A CD1 1 ATOM 1372 C CD2 . TYR A 1 178 ? -17.431 -16.075 44.427 1.00 11.57 ? 178 TYR A CD2 1 ATOM 1373 C CE1 . TYR A 1 178 ? -18.997 -17.453 42.602 1.00 10.19 ? 178 TYR A CE1 1 ATOM 1374 C CE2 . TYR A 1 178 ? -18.771 -16.411 44.755 1.00 11.95 ? 178 TYR A CE2 1 ATOM 1375 C CZ . TYR A 1 178 ? -19.509 -17.108 43.843 1.00 10.64 ? 178 TYR A CZ 1 ATOM 1376 O OH . TYR A 1 178 ? -20.843 -17.417 44.131 1.00 14.04 ? 178 TYR A OH 1 ATOM 1377 N N . GLY A 1 179 ? -12.363 -17.019 42.121 1.00 13.58 ? 179 GLY A N 1 ATOM 1378 C CA . GLY A 1 179 ? -11.002 -16.438 42.011 1.00 12.04 ? 179 GLY A CA 1 ATOM 1379 C C . GLY A 1 179 ? -9.949 -17.503 41.786 1.00 13.17 ? 179 GLY A C 1 ATOM 1380 O O . GLY A 1 179 ? -10.270 -18.605 41.361 1.00 13.48 ? 179 GLY A O 1 ATOM 1381 N N . LEU A 1 180 ? -8.705 -17.162 42.112 1.00 12.76 ? 180 LEU A N 1 ATOM 1382 C CA . LEU A 1 180 ? -7.515 -17.986 41.865 1.00 14.34 ? 180 LEU A CA 1 ATOM 1383 C C . LEU A 1 180 ? -7.209 -17.974 40.389 1.00 14.34 ? 180 LEU A C 1 ATOM 1384 O O . LEU A 1 180 ? -8.112 -17.897 39.548 1.00 15.10 ? 180 LEU A O 1 ATOM 1385 C CB . LEU A 1 180 ? -7.653 -19.427 42.371 1.00 14.09 ? 180 LEU A CB 1 ATOM 1386 C CG . LEU A 1 180 ? -8.077 -19.607 43.839 1.00 15.32 ? 180 LEU A CG 1 ATOM 1387 C CD1 . LEU A 1 180 ? -8.397 -21.080 44.076 1.00 19.10 ? 180 LEU A CD1 1 ATOM 1388 C CD2 . LEU A 1 180 ? -7.043 -19.071 44.850 1.00 16.90 ? 180 LEU A CD2 1 ATOM 1389 N N . GLY A 1 181 ? -5.930 -18.049 40.045 1.00 13.44 ? 181 GLY A N 1 ATOM 1390 C CA . GLY A 1 181 ? -5.570 -17.972 38.644 1.00 13.71 ? 181 GLY A CA 1 ATOM 1391 C C . GLY A 1 181 ? -4.066 -18.116 38.463 1.00 13.99 ? 181 GLY A C 1 ATOM 1392 O O . GLY A 1 181 ? -3.354 -18.123 39.443 1.00 14.74 ? 181 GLY A O 1 ATOM 1393 N N . GLU A 1 182 ? -3.595 -18.181 37.219 1.00 14.47 ? 182 GLU A N 1 ATOM 1394 C CA . GLU A 1 182 ? -4.471 -18.175 36.030 1.00 14.78 ? 182 GLU A CA 1 ATOM 1395 C C . GLU A 1 182 ? -4.810 -19.591 35.581 1.00 15.08 ? 182 GLU A C 1 ATOM 1396 O O . GLU A 1 182 ? -3.914 -20.407 35.442 1.00 14.61 ? 182 GLU A O 1 ATOM 1397 C CB . GLU A 1 182 ? -3.816 -17.449 34.876 1.00 15.82 ? 182 GLU A CB 1 ATOM 1398 C CG . GLU A 1 182 ? -4.768 -17.273 33.705 1.00 14.60 ? 182 GLU A CG 1 ATOM 1399 C CD . GLU A 1 182 ? -4.216 -16.337 32.645 1.00 21.16 ? 182 GLU A CD 1 ATOM 1400 O OE1 . GLU A 1 182 ? -3.021 -15.947 32.736 1.00 20.52 ? 182 GLU A OE1 1 ATOM 1401 O OE2 . GLU A 1 182 ? -4.976 -16.008 31.717 1.00 20.58 ? 182 GLU A OE2 1 ATOM 1402 N N . HIS A 1 183 ? -6.099 -19.897 35.405 1.00 14.38 ? 183 HIS A N 1 ATOM 1403 C CA . HIS A 1 183 ? -6.508 -21.262 35.044 1.00 14.87 ? 183 HIS A CA 1 ATOM 1404 C C . HIS A 1 183 ? -7.747 -21.163 34.154 1.00 15.57 ? 183 HIS A C 1 ATOM 1405 O O . HIS A 1 183 ? -8.396 -20.106 34.081 1.00 15.86 ? 183 HIS A O 1 ATOM 1406 C CB . HIS A 1 183 ? -6.920 -22.143 36.274 1.00 15.36 ? 183 HIS A CB 1 ATOM 1407 C CG . HIS A 1 183 ? -6.042 -22.014 37.479 1.00 16.06 ? 183 HIS A CG 1 ATOM 1408 N ND1 . HIS A 1 183 ? -4.768 -22.556 37.552 1.00 17.69 ? 183 HIS A ND1 1 ATOM 1409 C CD2 . HIS A 1 183 ? -6.293 -21.482 38.688 1.00 10.73 ? 183 HIS A CD2 1 ATOM 1410 C CE1 . HIS A 1 183 ? -4.246 -22.279 38.730 1.00 12.10 ? 183 HIS A CE1 1 ATOM 1411 N NE2 . HIS A 1 183 ? -5.143 -21.606 39.431 1.00 16.90 ? 183 HIS A NE2 1 ATOM 1412 N N . VAL A 1 184 ? -8.113 -22.277 33.527 1.00 14.86 ? 184 VAL A N 1 ATOM 1413 C CA . VAL A 1 184 ? -9.450 -22.406 32.930 1.00 15.39 ? 184 VAL A CA 1 ATOM 1414 C C . VAL A 1 184 ? -10.252 -23.244 33.943 1.00 15.87 ? 184 VAL A C 1 ATOM 1415 O O . VAL A 1 184 ? -10.074 -24.460 34.051 1.00 16.10 ? 184 VAL A O 1 ATOM 1416 C CB . VAL A 1 184 ? -9.402 -23.029 31.496 1.00 14.86 ? 184 VAL A CB 1 ATOM 1417 C CG1 . VAL A 1 184 ? -10.814 -23.472 30.992 1.00 14.77 ? 184 VAL A CG1 1 ATOM 1418 C CG2 . VAL A 1 184 ? -8.729 -22.063 30.508 1.00 13.68 ? 184 VAL A CG2 1 ATOM 1419 N N . HIS A 1 185 ? -11.079 -22.590 34.752 1.00 16.17 ? 185 HIS A N 1 ATOM 1420 C CA . HIS A 1 185 ? -11.842 -23.327 35.778 1.00 16.12 ? 185 HIS A CA 1 ATOM 1421 C C . HIS A 1 185 ? -13.086 -23.967 35.191 1.00 16.95 ? 185 HIS A C 1 ATOM 1422 O O . HIS A 1 185 ? -13.687 -24.847 35.823 1.00 18.19 ? 185 HIS A O 1 ATOM 1423 C CB . HIS A 1 185 ? -12.250 -22.436 36.966 1.00 15.86 ? 185 HIS A CB 1 ATOM 1424 C CG . HIS A 1 185 ? -11.089 -21.812 37.683 1.00 15.93 ? 185 HIS A CG 1 ATOM 1425 N ND1 . HIS A 1 185 ? -11.046 -20.468 37.992 1.00 15.07 ? 185 HIS A ND1 1 ATOM 1426 C CD2 . HIS A 1 185 ? -9.916 -22.338 38.127 1.00 16.58 ? 185 HIS A CD2 1 ATOM 1427 C CE1 . HIS A 1 185 ? -9.897 -20.192 38.590 1.00 17.37 ? 185 HIS A CE1 1 ATOM 1428 N NE2 . HIS A 1 185 ? -9.193 -21.309 38.687 1.00 14.94 ? 185 HIS A NE2 1 ATOM 1429 N N . GLN A 1 186 ? -13.499 -23.470 34.030 1.00 18.43 ? 186 GLN A N 1 ATOM 1430 C CA . GLN A 1 186 ? -14.675 -23.932 33.281 1.00 20.02 ? 186 GLN A CA 1 ATOM 1431 C C . GLN A 1 186 ? -15.961 -23.386 33.903 1.00 20.37 ? 186 GLN A C 1 ATOM 1432 O O . GLN A 1 186 ? -16.853 -22.926 33.206 1.00 22.88 ? 186 GLN A O 1 ATOM 1433 C CB . GLN A 1 186 ? -14.691 -25.450 33.097 1.00 19.93 ? 186 GLN A CB 1 ATOM 1434 C CG . GLN A 1 186 ? -13.343 -25.988 32.557 1.00 19.98 ? 186 GLN A CG 1 ATOM 1435 C CD . GLN A 1 186 ? -13.430 -27.423 32.162 1.00 23.24 ? 186 GLN A CD 1 ATOM 1436 O OE1 . GLN A 1 186 ? -14.522 -27.952 31.935 1.00 22.35 ? 186 GLN A OE1 1 ATOM 1437 N NE2 . GLN A 1 186 ? -12.297 -28.069 32.071 1.00 22.88 ? 186 GLN A NE2 1 ATOM 1438 N N . GLN A 1 187 ? -16.034 -23.358 35.220 1.00 20.85 ? 187 GLN A N 1 ATOM 1439 C CA . GLN A 1 187 ? -17.159 -22.702 35.889 1.00 20.26 ? 187 GLN A CA 1 ATOM 1440 C C . GLN A 1 187 ? -16.606 -21.510 36.670 1.00 19.26 ? 187 GLN A C 1 ATOM 1441 O O . GLN A 1 187 ? -15.409 -21.393 36.815 1.00 18.25 ? 187 GLN A O 1 ATOM 1442 C CB . GLN A 1 187 ? -17.829 -23.699 36.803 1.00 21.60 ? 187 GLN A CB 1 ATOM 1443 C CG . GLN A 1 187 ? -16.831 -24.384 37.739 1.00 25.31 ? 187 GLN A CG 1 ATOM 1444 C CD . GLN A 1 187 ? -17.397 -25.630 38.363 1.00 31.65 ? 187 GLN A CD 1 ATOM 1445 O OE1 . GLN A 1 187 ? -17.695 -25.653 39.554 1.00 36.26 ? 187 GLN A OE1 1 ATOM 1446 N NE2 . GLN A 1 187 ? -17.556 -26.672 37.563 1.00 34.46 ? 187 GLN A NE2 1 ATOM 1447 N N . TYR A 1 188 ? -17.471 -20.624 37.158 1.00 17.20 ? 188 TYR A N 1 ATOM 1448 C CA . TYR A 1 188 ? -17.031 -19.474 37.901 1.00 16.98 ? 188 TYR A CA 1 ATOM 1449 C C . TYR A 1 188 ? -17.050 -19.751 39.420 1.00 16.92 ? 188 TYR A C 1 ATOM 1450 O O . TYR A 1 188 ? -16.070 -19.468 40.121 1.00 15.90 ? 188 TYR A O 1 ATOM 1451 C CB . TYR A 1 188 ? -17.883 -18.232 37.552 1.00 16.31 ? 188 TYR A CB 1 ATOM 1452 C CG . TYR A 1 188 ? -17.444 -16.980 38.258 1.00 15.10 ? 188 TYR A CG 1 ATOM 1453 C CD1 . TYR A 1 188 ? -16.117 -16.523 38.162 1.00 14.65 ? 188 TYR A CD1 1 ATOM 1454 C CD2 . TYR A 1 188 ? -18.337 -16.263 39.054 1.00 12.21 ? 188 TYR A CD2 1 ATOM 1455 C CE1 . TYR A 1 188 ? -15.703 -15.366 38.819 1.00 15.33 ? 188 TYR A CE1 1 ATOM 1456 C CE2 . TYR A 1 188 ? -17.938 -15.091 39.710 1.00 13.95 ? 188 TYR A CE2 1 ATOM 1457 C CZ . TYR A 1 188 ? -16.594 -14.670 39.592 1.00 13.05 ? 188 TYR A CZ 1 ATOM 1458 O OH . TYR A 1 188 ? -16.175 -13.548 40.221 1.00 13.63 ? 188 TYR A OH 1 ATOM 1459 N N . ARG A 1 189 ? -18.138 -20.319 39.945 1.00 15.07 ? 189 ARG A N 1 ATOM 1460 C CA . ARG A 1 189 ? -18.111 -20.698 41.368 1.00 15.07 ? 189 ARG A CA 1 ATOM 1461 C C . ARG A 1 189 ? -17.296 -21.976 41.500 1.00 15.94 ? 189 ARG A C 1 ATOM 1462 O O . ARG A 1 189 ? -17.463 -22.936 40.746 1.00 16.95 ? 189 ARG A O 1 ATOM 1463 C CB . ARG A 1 189 ? -19.488 -20.927 41.963 1.00 15.98 ? 189 ARG A CB 1 ATOM 1464 C CG . ARG A 1 189 ? -19.412 -21.148 43.468 1.00 17.05 ? 189 ARG A CG 1 ATOM 1465 C CD . ARG A 1 189 ? -20.790 -21.261 44.071 1.00 17.49 ? 189 ARG A CD 1 ATOM 1466 N NE . ARG A 1 189 ? -21.470 -22.459 43.594 1.00 19.65 ? 189 ARG A NE 1 ATOM 1467 C CZ . ARG A 1 189 ? -22.752 -22.721 43.892 1.00 27.63 ? 189 ARG A CZ 1 ATOM 1468 N NH1 . ARG A 1 189 ? -23.426 -21.904 44.689 1.00 25.55 ? 189 ARG A NH1 1 ATOM 1469 N NH2 . ARG A 1 189 ? -23.353 -23.813 43.429 1.00 28.24 ? 189 ARG A NH2 1 ATOM 1470 N N . HIS A 1 190 ? -16.411 -21.990 42.459 1.00 16.86 ? 190 HIS A N 1 ATOM 1471 C CA . HIS A 1 190 ? -15.474 -23.124 42.538 1.00 19.43 ? 190 HIS A CA 1 ATOM 1472 C C . HIS A 1 190 ? -16.091 -24.437 42.864 1.00 22.37 ? 190 HIS A C 1 ATOM 1473 O O . HIS A 1 190 ? -16.940 -24.507 43.740 1.00 21.66 ? 190 HIS A O 1 ATOM 1474 C CB . HIS A 1 190 ? -14.360 -22.808 43.504 1.00 18.58 ? 190 HIS A CB 1 ATOM 1475 C CG . HIS A 1 190 ? -13.162 -22.286 42.794 1.00 18.72 ? 190 HIS A CG 1 ATOM 1476 N ND1 . HIS A 1 190 ? -12.929 -20.941 42.607 1.00 20.27 ? 190 HIS A ND1 1 ATOM 1477 C CD2 . HIS A 1 190 ? -12.197 -22.936 42.115 1.00 19.30 ? 190 HIS A CD2 1 ATOM 1478 C CE1 . HIS A 1 190 ? -11.835 -20.783 41.883 1.00 16.85 ? 190 HIS A CE1 1 ATOM 1479 N NE2 . HIS A 1 190 ? -11.361 -21.982 41.588 1.00 21.28 ? 190 HIS A NE2 1 ATOM 1480 N N . ASP A 1 191 ? -15.660 -25.470 42.122 1.00 24.80 ? 191 ASP A N 1 ATOM 1481 C CA . ASP A 1 191 ? -15.853 -26.845 42.550 1.00 26.17 ? 191 ASP A CA 1 ATOM 1482 C C . ASP A 1 191 ? -15.059 -27.052 43.834 1.00 26.05 ? 191 ASP A C 1 ATOM 1483 O O . ASP A 1 191 ? -13.806 -27.124 43.802 1.00 24.03 ? 191 ASP A O 1 ATOM 1484 C CB . ASP A 1 191 ? -15.383 -27.822 41.465 1.00 27.62 ? 191 ASP A CB 1 ATOM 1485 C CG . ASP A 1 191 ? -15.847 -29.235 41.734 1.00 31.23 ? 191 ASP A CG 1 ATOM 1486 O OD1 . ASP A 1 191 ? -16.361 -29.469 42.852 1.00 33.42 ? 191 ASP A OD1 1 ATOM 1487 O OD2 . ASP A 1 191 ? -15.707 -30.098 40.841 1.00 37.56 ? 191 ASP A OD2 1 ATOM 1488 N N . MET A 1 192 ? -15.770 -27.134 44.970 1.00 25.21 ? 192 MET A N 1 ATOM 1489 C CA . MET A 1 192 ? -15.091 -27.407 46.250 1.00 25.14 ? 192 MET A CA 1 ATOM 1490 C C . MET A 1 192 ? -14.824 -28.898 46.512 1.00 25.95 ? 192 MET A C 1 ATOM 1491 O O . MET A 1 192 ? -14.338 -29.246 47.575 1.00 24.23 ? 192 MET A O 1 ATOM 1492 C CB . MET A 1 192 ? -15.811 -26.764 47.451 1.00 23.73 ? 192 MET A CB 1 ATOM 1493 C CG . MET A 1 192 ? -15.897 -25.201 47.475 1.00 23.68 ? 192 MET A CG 1 ATOM 1494 S SD . MET A 1 192 ? -14.330 -24.292 47.345 1.00 25.15 ? 192 MET A SD 1 ATOM 1495 C CE . MET A 1 192 ? -13.608 -24.592 48.978 1.00 19.54 ? 192 MET A CE 1 ATOM 1496 N N . ASN A 1 193 ? -15.119 -29.769 45.544 1.00 26.72 ? 193 ASN A N 1 ATOM 1497 C CA . ASN A 1 193 ? -14.972 -31.210 45.725 1.00 26.89 ? 193 ASN A CA 1 ATOM 1498 C C . ASN A 1 193 ? -13.569 -31.811 45.462 1.00 25.83 ? 193 ASN A C 1 ATOM 1499 O O . ASN A 1 193 ? -13.365 -32.521 44.461 1.00 27.47 ? 193 ASN A O 1 ATOM 1500 C CB . ASN A 1 193 ? -16.028 -31.966 44.907 1.00 28.48 ? 193 ASN A CB 1 ATOM 1501 C CG . ASN A 1 193 ? -17.447 -31.622 45.336 1.00 32.21 ? 193 ASN A CG 1 ATOM 1502 O OD1 . ASN A 1 193 ? -18.242 -31.141 44.527 1.00 38.83 ? 193 ASN A OD1 1 ATOM 1503 N ND2 . ASN A 1 193 ? -17.765 -31.845 46.612 1.00 35.92 ? 193 ASN A ND2 1 ATOM 1504 N N . TRP A 1 194 ? -12.640 -31.537 46.369 1.00 22.30 ? 194 TRP A N 1 ATOM 1505 C CA . TRP A 1 194 ? -11.281 -32.059 46.324 1.00 20.51 ? 194 TRP A CA 1 ATOM 1506 C C . TRP A 1 194 ? -10.724 -31.677 44.981 1.00 19.96 ? 194 TRP A C 1 ATOM 1507 O O . TRP A 1 194 ? -10.874 -32.426 44.020 1.00 22.87 ? 194 TRP A O 1 ATOM 1508 C CB . TRP A 1 194 ? -11.307 -33.584 46.531 1.00 19.05 ? 194 TRP A CB 1 ATOM 1509 C CG . TRP A 1 194 ? -12.053 -34.004 47.803 1.00 16.19 ? 194 TRP A CG 1 ATOM 1510 C CD1 . TRP A 1 194 ? -13.327 -34.549 47.891 1.00 18.62 ? 194 TRP A CD1 1 ATOM 1511 C CD2 . TRP A 1 194 ? -11.559 -33.926 49.141 1.00 16.53 ? 194 TRP A CD2 1 ATOM 1512 N NE1 . TRP A 1 194 ? -13.635 -34.796 49.209 1.00 16.50 ? 194 TRP A NE1 1 ATOM 1513 C CE2 . TRP A 1 194 ? -12.571 -34.418 49.994 1.00 15.47 ? 194 TRP A CE2 1 ATOM 1514 C CE3 . TRP A 1 194 ? -10.334 -33.480 49.708 1.00 14.91 ? 194 TRP A CE3 1 ATOM 1515 C CZ2 . TRP A 1 194 ? -12.406 -34.500 51.385 1.00 14.94 ? 194 TRP A CZ2 1 ATOM 1516 C CZ3 . TRP A 1 194 ? -10.180 -33.536 51.075 1.00 15.79 ? 194 TRP A CZ3 1 ATOM 1517 C CH2 . TRP A 1 194 ? -11.215 -34.038 51.907 1.00 17.33 ? 194 TRP A CH2 1 ATOM 1518 N N . LYS A 1 195 ? -10.219 -30.458 44.872 1.00 18.21 ? 195 LYS A N 1 ATOM 1519 C CA . LYS A 1 195 ? -9.625 -29.966 43.630 1.00 17.77 ? 195 LYS A CA 1 ATOM 1520 C C . LYS A 1 195 ? -8.324 -29.283 43.990 1.00 16.67 ? 195 LYS A C 1 ATOM 1521 O O . LYS A 1 195 ? -8.259 -28.560 44.982 1.00 16.28 ? 195 LYS A O 1 ATOM 1522 C CB . LYS A 1 195 ? -10.545 -28.932 42.966 1.00 19.27 ? 195 LYS A CB 1 ATOM 1523 C CG . LYS A 1 195 ? -11.693 -29.517 42.107 1.00 23.33 ? 195 LYS A CG 1 ATOM 1524 C CD . LYS A 1 195 ? -11.130 -30.167 40.783 1.00 27.86 ? 195 LYS A CD 1 ATOM 1525 C CE . LYS A 1 195 ? -10.007 -29.294 40.133 1.00 30.44 ? 195 LYS A CE 1 ATOM 1526 N NZ . LYS A 1 195 ? -9.435 -29.702 38.779 1.00 31.95 ? 195 LYS A NZ 1 ATOM 1527 N N . THR A 1 196 ? -7.285 -29.536 43.211 1.00 15.19 ? 196 THR A N 1 ATOM 1528 C CA . THR A 1 196 ? -6.000 -28.849 43.437 1.00 14.40 ? 196 THR A CA 1 ATOM 1529 C C . THR A 1 196 ? -5.670 -28.012 42.205 1.00 13.95 ? 196 THR A C 1 ATOM 1530 O O . THR A 1 196 ? -5.724 -28.550 41.089 1.00 14.63 ? 196 THR A O 1 ATOM 1531 C CB . THR A 1 196 ? -4.845 -29.896 43.726 1.00 15.27 ? 196 THR A CB 1 ATOM 1532 O OG1 . THR A 1 196 ? -5.108 -30.610 44.953 1.00 16.00 ? 196 THR A OG1 1 ATOM 1533 C CG2 . THR A 1 196 ? -3.550 -29.176 43.900 1.00 15.95 ? 196 THR A CG2 1 ATOM 1534 N N . TRP A 1 197 ? -5.352 -26.710 42.396 1.00 14.77 ? 197 TRP A N 1 ATOM 1535 C CA . TRP A 1 197 ? -5.003 -25.762 41.325 1.00 14.24 ? 197 TRP A CA 1 ATOM 1536 C C . TRP A 1 197 ? -3.582 -25.276 41.474 1.00 14.16 ? 197 TRP A C 1 ATOM 1537 O O . TRP A 1 197 ? -3.274 -24.593 42.449 1.00 14.56 ? 197 TRP A O 1 ATOM 1538 C CB . TRP A 1 197 ? -5.934 -24.543 41.325 1.00 15.21 ? 197 TRP A CB 1 ATOM 1539 C CG . TRP A 1 197 ? -7.349 -24.947 41.007 1.00 13.62 ? 197 TRP A CG 1 ATOM 1540 C CD1 . TRP A 1 197 ? -8.350 -25.174 41.902 1.00 18.60 ? 197 TRP A CD1 1 ATOM 1541 C CD2 . TRP A 1 197 ? -7.891 -25.213 39.712 1.00 14.88 ? 197 TRP A CD2 1 ATOM 1542 N NE1 . TRP A 1 197 ? -9.496 -25.563 41.244 1.00 17.75 ? 197 TRP A NE1 1 ATOM 1543 C CE2 . TRP A 1 197 ? -9.242 -25.595 39.899 1.00 15.52 ? 197 TRP A CE2 1 ATOM 1544 C CE3 . TRP A 1 197 ? -7.366 -25.197 38.399 1.00 12.79 ? 197 TRP A CE3 1 ATOM 1545 C CZ2 . TRP A 1 197 ? -10.079 -25.928 38.836 1.00 15.24 ? 197 TRP A CZ2 1 ATOM 1546 C CZ3 . TRP A 1 197 ? -8.228 -25.509 37.331 1.00 16.39 ? 197 TRP A CZ3 1 ATOM 1547 C CH2 . TRP A 1 197 ? -9.570 -25.875 37.573 1.00 15.12 ? 197 TRP A CH2 1 ATOM 1548 N N . PRO A 1 198 ? -2.702 -25.685 40.547 1.00 14.74 ? 198 PRO A N 1 ATOM 1549 C CA . PRO A 1 198 ? -1.316 -25.232 40.606 1.00 14.82 ? 198 PRO A CA 1 ATOM 1550 C C . PRO A 1 198 ? -1.170 -23.815 40.034 1.00 14.01 ? 198 PRO A C 1 ATOM 1551 O O . PRO A 1 198 ? -1.840 -23.463 39.062 1.00 13.61 ? 198 PRO A O 1 ATOM 1552 C CB . PRO A 1 198 ? -0.616 -26.257 39.713 1.00 15.06 ? 198 PRO A CB 1 ATOM 1553 C CG . PRO A 1 198 ? -1.634 -26.570 38.641 1.00 16.16 ? 198 PRO A CG 1 ATOM 1554 C CD . PRO A 1 198 ? -2.931 -26.633 39.429 1.00 13.84 ? 198 PRO A CD 1 ATOM 1555 N N . ILE A 1 199 ? -0.278 -23.013 40.608 1.00 14.05 ? 199 ILE A N 1 ATOM 1556 C CA . ILE A 1 199 ? -0.070 -21.663 40.162 1.00 13.95 ? 199 ILE A CA 1 ATOM 1557 C C . ILE A 1 199 ? 1.437 -21.496 39.925 1.00 13.90 ? 199 ILE A C 1 ATOM 1558 O O . ILE A 1 199 ? 2.220 -21.556 40.862 1.00 13.51 ? 199 ILE A O 1 ATOM 1559 C CB . ILE A 1 199 ? -0.589 -20.655 41.212 1.00 14.84 ? 199 ILE A CB 1 ATOM 1560 C CG1 . ILE A 1 199 ? -2.122 -20.835 41.424 1.00 15.05 ? 199 ILE A CG1 1 ATOM 1561 C CG2 . ILE A 1 199 ? -0.223 -19.242 40.802 1.00 16.09 ? 199 ILE A CG2 1 ATOM 1562 C CD1 . ILE A 1 199 ? -2.719 -19.993 42.588 1.00 14.59 ? 199 ILE A CD1 1 ATOM 1563 N N . PHE A 1 200 ? 1.805 -21.331 38.667 1.00 13.16 ? 200 PHE A N 1 ATOM 1564 C CA . PHE A 1 200 ? 3.217 -21.128 38.273 1.00 14.22 ? 200 PHE A CA 1 ATOM 1565 C C . PHE A 1 200 ? 3.188 -20.724 36.826 1.00 12.97 ? 200 PHE A C 1 ATOM 1566 O O . PHE A 1 200 ? 2.742 -21.483 35.958 1.00 15.01 ? 200 PHE A O 1 ATOM 1567 C CB . PHE A 1 200 ? 4.000 -22.432 38.434 1.00 13.83 ? 200 PHE A CB 1 ATOM 1568 C CG . PHE A 1 200 ? 5.487 -22.249 38.316 1.00 16.55 ? 200 PHE A CG 1 ATOM 1569 C CD1 . PHE A 1 200 ? 6.165 -21.490 39.252 1.00 15.69 ? 200 PHE A CD1 1 ATOM 1570 C CD2 . PHE A 1 200 ? 6.157 -22.775 37.241 1.00 17.76 ? 200 PHE A CD2 1 ATOM 1571 C CE1 . PHE A 1 200 ? 7.605 -21.316 39.163 1.00 17.52 ? 200 PHE A CE1 1 ATOM 1572 C CE2 . PHE A 1 200 ? 7.547 -22.583 37.114 1.00 20.93 ? 200 PHE A CE2 1 ATOM 1573 C CZ . PHE A 1 200 ? 8.242 -21.871 38.066 1.00 17.34 ? 200 PHE A CZ 1 ATOM 1574 N N . ASN A 1 201 ? 3.640 -19.500 36.565 1.00 14.26 ? 201 ASN A N 1 ATOM 1575 C CA . ASN A 1 201 ? 3.535 -18.882 35.260 1.00 13.98 ? 201 ASN A CA 1 ATOM 1576 C C . ASN A 1 201 ? 4.102 -19.729 34.161 1.00 14.83 ? 201 ASN A C 1 ATOM 1577 O O . ASN A 1 201 ? 5.272 -20.131 34.183 1.00 13.53 ? 201 ASN A O 1 ATOM 1578 C CB . ASN A 1 201 ? 4.117 -17.475 35.297 1.00 14.38 ? 201 ASN A CB 1 ATOM 1579 C CG . ASN A 1 201 ? 3.296 -16.544 36.201 1.00 14.70 ? 201 ASN A CG 1 ATOM 1580 O OD1 . ASN A 1 201 ? 2.277 -16.966 36.771 1.00 18.70 ? 201 ASN A OD1 1 ATOM 1581 N ND2 . ASN A 1 201 ? 3.678 -15.281 36.270 1.00 14.37 ? 201 ASN A ND2 1 ATOM 1582 N N . ARG A 1 202 ? 3.235 -20.062 33.221 1.00 14.55 ? 202 ARG A N 1 ATOM 1583 C CA . ARG A 1 202 ? 3.584 -21.075 32.224 1.00 15.25 ? 202 ARG A CA 1 ATOM 1584 C C . ARG A 1 202 ? 2.876 -20.808 30.899 1.00 15.62 ? 202 ARG A C 1 ATOM 1585 O O . ARG A 1 202 ? 1.665 -20.580 30.865 1.00 14.54 ? 202 ARG A O 1 ATOM 1586 C CB . ARG A 1 202 ? 3.269 -22.494 32.761 1.00 14.52 ? 202 ARG A CB 1 ATOM 1587 C CG . ARG A 1 202 ? 3.306 -23.605 31.702 1.00 16.25 ? 202 ARG A CG 1 ATOM 1588 C CD . ARG A 1 202 ? 4.753 -23.872 31.180 1.00 17.62 ? 202 ARG A CD 1 ATOM 1589 N NE . ARG A 1 202 ? 4.725 -24.756 30.015 1.00 18.98 ? 202 ARG A NE 1 ATOM 1590 C CZ . ARG A 1 202 ? 4.884 -26.079 30.059 1.00 18.96 ? 202 ARG A CZ 1 ATOM 1591 N NH1 . ARG A 1 202 ? 5.131 -26.699 31.210 1.00 17.70 ? 202 ARG A NH1 1 ATOM 1592 N NH2 . ARG A 1 202 ? 4.800 -26.785 28.935 1.00 18.05 ? 202 ARG A NH2 1 ATOM 1593 N N . ASP A 1 203 ? 3.653 -20.842 29.815 1.00 16.39 ? 203 ASP A N 1 ATOM 1594 C CA . ASP A 1 203 ? 3.134 -20.883 28.462 1.00 17.66 ? 203 ASP A CA 1 ATOM 1595 C C . ASP A 1 203 ? 2.512 -22.251 28.186 1.00 18.31 ? 203 ASP A C 1 ATOM 1596 O O . ASP A 1 203 ? 3.213 -23.237 27.912 1.00 17.65 ? 203 ASP A O 1 ATOM 1597 C CB . ASP A 1 203 ? 4.266 -20.562 27.478 1.00 18.16 ? 203 ASP A CB 1 ATOM 1598 C CG . ASP A 1 203 ? 3.820 -20.541 26.040 1.00 20.99 ? 203 ASP A CG 1 ATOM 1599 O OD1 . ASP A 1 203 ? 2.643 -20.885 25.734 1.00 21.57 ? 203 ASP A OD1 1 ATOM 1600 O OD2 . ASP A 1 203 ? 4.668 -20.154 25.205 1.00 21.99 ? 203 ASP A OD2 1 ATOM 1601 N N . THR A 1 204 ? 1.192 -22.332 28.317 1.00 18.61 ? 204 THR A N 1 ATOM 1602 C CA . THR A 1 204 ? 0.493 -23.577 28.044 1.00 21.35 ? 204 THR A CA 1 ATOM 1603 C C . THR A 1 204 ? -0.881 -23.258 27.521 1.00 20.62 ? 204 THR A C 1 ATOM 1604 O O . THR A 1 204 ? -1.386 -22.156 27.744 1.00 20.32 ? 204 THR A O 1 ATOM 1605 C CB . THR A 1 204 ? 0.341 -24.476 29.264 1.00 21.88 ? 204 THR A CB 1 ATOM 1606 O OG1 . THR A 1 204 ? 0.075 -23.702 30.422 1.00 30.28 ? 204 THR A OG1 1 ATOM 1607 C CG2 . THR A 1 204 ? 1.597 -25.267 29.522 1.00 27.88 ? 204 THR A CG2 1 ATOM 1608 N N . THR A 1 205 ? -1.494 -24.220 26.840 1.00 19.76 ? 205 THR A N 1 ATOM 1609 C CA . THR A 1 205 ? -2.789 -23.971 26.225 1.00 20.08 ? 205 THR A CA 1 ATOM 1610 C C . THR A 1 205 ? -3.879 -23.885 27.299 1.00 19.27 ? 205 THR A C 1 ATOM 1611 O O . THR A 1 205 ? -4.020 -24.792 28.122 1.00 18.04 ? 205 THR A O 1 ATOM 1612 C CB . THR A 1 205 ? -3.141 -25.087 25.227 1.00 21.13 ? 205 THR A CB 1 ATOM 1613 O OG1 . THR A 1 205 ? -2.032 -25.287 24.338 1.00 24.89 ? 205 THR A OG1 1 ATOM 1614 C CG2 . THR A 1 205 ? -4.369 -24.703 24.429 1.00 20.97 ? 205 THR A CG2 1 ATOM 1615 N N . PRO A 1 206 ? -4.649 -22.788 27.294 1.00 18.60 ? 206 PRO A N 1 ATOM 1616 C CA . PRO A 1 206 ? -5.797 -22.754 28.188 1.00 19.02 ? 206 PRO A CA 1 ATOM 1617 C C . PRO A 1 206 ? -6.840 -23.745 27.699 1.00 19.62 ? 206 PRO A C 1 ATOM 1618 O O . PRO A 1 206 ? -7.671 -23.404 26.876 1.00 21.39 ? 206 PRO A O 1 ATOM 1619 C CB . PRO A 1 206 ? -6.321 -21.312 28.082 1.00 17.63 ? 206 PRO A CB 1 ATOM 1620 C CG . PRO A 1 206 ? -5.730 -20.736 26.821 1.00 19.03 ? 206 PRO A CG 1 ATOM 1621 C CD . PRO A 1 206 ? -4.479 -21.554 26.492 1.00 19.64 ? 206 PRO A CD 1 ATOM 1622 N N . ASN A 1 207 ? -6.801 -24.962 28.204 1.00 20.76 ? 207 ASN A N 1 ATOM 1623 C CA . ASN A 1 207 ? -7.747 -25.985 27.726 1.00 20.59 ? 207 ASN A CA 1 ATOM 1624 C C . ASN A 1 207 ? -8.462 -26.628 28.904 1.00 20.73 ? 207 ASN A C 1 ATOM 1625 O O . ASN A 1 207 ? -8.419 -26.107 30.020 1.00 19.37 ? 207 ASN A O 1 ATOM 1626 C CB . ASN A 1 207 ? -6.997 -27.004 26.868 1.00 21.47 ? 207 ASN A CB 1 ATOM 1627 C CG . ASN A 1 207 ? -5.870 -27.661 27.614 1.00 21.22 ? 207 ASN A CG 1 ATOM 1628 O OD1 . ASN A 1 207 ? -5.897 -27.734 28.834 1.00 24.25 ? 207 ASN A OD1 1 ATOM 1629 N ND2 . ASN A 1 207 ? -4.868 -28.134 26.895 1.00 22.90 ? 207 ASN A ND2 1 ATOM 1630 N N . GLY A 1 208 ? -9.122 -27.758 28.661 1.00 20.45 ? 208 GLY A N 1 ATOM 1631 C CA . GLY A 1 208 ? -9.883 -28.431 29.693 1.00 21.80 ? 208 GLY A CA 1 ATOM 1632 C C . GLY A 1 208 ? -9.102 -29.203 30.734 1.00 22.11 ? 208 GLY A C 1 ATOM 1633 O O . GLY A 1 208 ? -9.707 -29.834 31.579 1.00 21.22 ? 208 GLY A O 1 ATOM 1634 N N . ASN A 1 209 ? -7.765 -29.142 30.687 1.00 22.27 ? 209 ASN A N 1 ATOM 1635 C CA . ASN A 1 209 ? -6.932 -29.904 31.605 1.00 22.12 ? 209 ASN A CA 1 ATOM 1636 C C . ASN A 1 209 ? -6.622 -29.260 32.967 1.00 21.90 ? 209 ASN A C 1 ATOM 1637 O O . ASN A 1 209 ? -5.956 -29.876 33.797 1.00 21.64 ? 209 ASN A O 1 ATOM 1638 C CB . ASN A 1 209 ? -5.612 -30.294 30.922 1.00 22.99 ? 209 ASN A CB 1 ATOM 1639 C CG . ASN A 1 209 ? -5.814 -31.333 29.839 1.00 27.61 ? 209 ASN A CG 1 ATOM 1640 O OD1 . ASN A 1 209 ? -6.689 -32.204 29.956 1.00 32.65 ? 209 ASN A OD1 1 ATOM 1641 N ND2 . ASN A 1 209 ? -5.028 -31.245 28.774 1.00 32.90 ? 209 ASN A ND2 1 ATOM 1642 N N . GLY A 1 210 ? -7.078 -28.038 33.189 1.00 19.92 ? 210 GLY A N 1 ATOM 1643 C CA . GLY A 1 210 ? -6.902 -27.402 34.500 1.00 18.76 ? 210 GLY A CA 1 ATOM 1644 C C . GLY A 1 210 ? -5.465 -27.211 34.960 1.00 18.27 ? 210 GLY A C 1 ATOM 1645 O O . GLY A 1 210 ? -5.178 -27.323 36.155 1.00 19.14 ? 210 GLY A O 1 ATOM 1646 N N . THR A 1 211 ? -4.568 -26.893 34.032 1.00 15.45 ? 211 THR A N 1 ATOM 1647 C CA . THR A 1 211 ? -3.167 -26.633 34.385 1.00 15.55 ? 211 THR A CA 1 ATOM 1648 C C . THR A 1 211 ? -2.921 -25.206 34.857 1.00 14.54 ? 211 THR A C 1 ATOM 1649 O O . THR A 1 211 ? -3.752 -24.307 34.643 1.00 13.65 ? 211 THR A O 1 ATOM 1650 C CB . THR A 1 211 ? -2.187 -26.910 33.182 1.00 14.48 ? 211 THR A CB 1 ATOM 1651 O OG1 . THR A 1 211 ? -2.332 -25.881 32.188 1.00 15.91 ? 211 THR A OG1 1 ATOM 1652 C CG2 . THR A 1 211 ? -2.436 -28.269 32.544 1.00 17.28 ? 211 THR A CG2 1 ATOM 1653 N N . ASN A 1 212 ? -1.760 -24.989 35.478 1.00 12.52 ? 212 ASN A N 1 ATOM 1654 C CA . ASN A 1 212 ? -1.247 -23.639 35.588 1.00 13.95 ? 212 ASN A CA 1 ATOM 1655 C C . ASN A 1 212 ? -1.098 -23.004 34.197 1.00 13.98 ? 212 ASN A C 1 ATOM 1656 O O . ASN A 1 212 ? -0.715 -23.686 33.247 1.00 14.80 ? 212 ASN A O 1 ATOM 1657 C CB . ASN A 1 212 ? 0.122 -23.638 36.288 1.00 13.76 ? 212 ASN A CB 1 ATOM 1658 C CG . ASN A 1 212 ? 1.083 -24.675 35.709 1.00 15.10 ? 212 ASN A CG 1 ATOM 1659 O OD1 . ASN A 1 212 ? 0.729 -25.853 35.550 1.00 16.14 ? 212 ASN A OD1 1 ATOM 1660 N ND2 . ASN A 1 212 ? 2.313 -24.248 35.444 1.00 13.86 ? 212 ASN A ND2 1 ATOM 1661 N N . LEU A 1 213 ? -1.451 -21.714 34.082 1.00 12.47 ? 213 LEU A N 1 ATOM 1662 C CA . LEU A 1 213 ? -1.365 -20.988 32.831 1.00 12.61 ? 213 LEU A CA 1 ATOM 1663 C C . LEU A 1 213 ? -0.451 -19.778 33.015 1.00 13.15 ? 213 LEU A C 1 ATOM 1664 O O . LEU A 1 213 ? 0.487 -19.819 33.815 1.00 12.80 ? 213 LEU A O 1 ATOM 1665 C CB . LEU A 1 213 ? -2.765 -20.592 32.284 1.00 12.08 ? 213 LEU A CB 1 ATOM 1666 C CG . LEU A 1 213 ? -3.702 -21.787 32.050 1.00 11.38 ? 213 LEU A CG 1 ATOM 1667 C CD1 . LEU A 1 213 ? -5.105 -21.199 31.751 1.00 12.99 ? 213 LEU A CD1 1 ATOM 1668 C CD2 . LEU A 1 213 ? -3.180 -22.654 30.917 1.00 14.45 ? 213 LEU A CD2 1 ATOM 1669 N N . TYR A 1 214 ? -0.730 -18.687 32.310 1.00 14.29 ? 214 TYR A N 1 ATOM 1670 C CA . TYR A 1 214 ? 0.266 -17.608 32.126 1.00 14.58 ? 214 TYR A CA 1 ATOM 1671 C C . TYR A 1 214 ? 0.627 -16.744 33.344 1.00 15.84 ? 214 TYR A C 1 ATOM 1672 O O . TYR A 1 214 ? 1.763 -16.227 33.419 1.00 14.75 ? 214 TYR A O 1 ATOM 1673 C CB . TYR A 1 214 ? -0.205 -16.685 30.987 1.00 15.04 ? 214 TYR A CB 1 ATOM 1674 C CG . TYR A 1 214 ? -0.660 -17.444 29.789 1.00 15.45 ? 214 TYR A CG 1 ATOM 1675 C CD1 . TYR A 1 214 ? 0.264 -18.042 28.948 1.00 13.90 ? 214 TYR A CD1 1 ATOM 1676 C CD2 . TYR A 1 214 ? -2.012 -17.599 29.503 1.00 11.47 ? 214 TYR A CD2 1 ATOM 1677 C CE1 . TYR A 1 214 ? -0.135 -18.767 27.845 1.00 16.12 ? 214 TYR A CE1 1 ATOM 1678 C CE2 . TYR A 1 214 ? -2.426 -18.343 28.409 1.00 16.66 ? 214 TYR A CE2 1 ATOM 1679 C CZ . TYR A 1 214 ? -1.475 -18.917 27.578 1.00 16.66 ? 214 TYR A CZ 1 ATOM 1680 O OH . TYR A 1 214 ? -1.845 -19.583 26.442 1.00 16.69 ? 214 TYR A OH 1 ATOM 1681 N N . GLY A 1 215 ? -0.310 -16.655 34.299 1.00 14.58 ? 215 GLY A N 1 ATOM 1682 C CA . GLY A 1 215 ? -0.272 -15.675 35.387 1.00 14.48 ? 215 GLY A CA 1 ATOM 1683 C C . GLY A 1 215 ? -0.481 -16.301 36.741 1.00 13.28 ? 215 GLY A C 1 ATOM 1684 O O . GLY A 1 215 ? -0.877 -17.441 36.841 1.00 13.67 ? 215 GLY A O 1 ATOM 1685 N N . ALA A 1 216 ? -0.247 -15.537 37.796 1.00 12.89 ? 216 ALA A N 1 ATOM 1686 C CA . ALA A 1 216 ? -0.287 -16.061 39.137 1.00 12.88 ? 216 ALA A CA 1 ATOM 1687 C C . ALA A 1 216 ? -1.114 -15.112 39.974 1.00 13.05 ? 216 ALA A C 1 ATOM 1688 O O . ALA A 1 216 ? -0.717 -13.955 40.189 1.00 15.05 ? 216 ALA A O 1 ATOM 1689 C CB . ALA A 1 216 ? 1.164 -16.124 39.711 1.00 12.68 ? 216 ALA A CB 1 ATOM 1690 N N . GLN A 1 217 ? -2.259 -15.599 40.410 1.00 13.39 ? 217 GLN A N 1 ATOM 1691 C CA . GLN A 1 217 ? -3.262 -14.795 41.101 1.00 13.64 ? 217 GLN A CA 1 ATOM 1692 C C . GLN A 1 217 ? -3.836 -15.598 42.277 1.00 14.21 ? 217 GLN A C 1 ATOM 1693 O O . GLN A 1 217 ? -4.620 -16.539 42.081 1.00 14.31 ? 217 GLN A O 1 ATOM 1694 C CB . GLN A 1 217 ? -4.383 -14.413 40.120 1.00 13.53 ? 217 GLN A CB 1 ATOM 1695 C CG . GLN A 1 217 ? -3.961 -13.585 38.849 1.00 13.12 ? 217 GLN A CG 1 ATOM 1696 C CD . GLN A 1 217 ? -3.507 -12.169 39.214 1.00 14.88 ? 217 GLN A CD 1 ATOM 1697 O OE1 . GLN A 1 217 ? -3.801 -11.655 40.308 1.00 13.40 ? 217 GLN A OE1 1 ATOM 1698 N NE2 . GLN A 1 217 ? -2.776 -11.541 38.306 1.00 15.09 ? 217 GLN A NE2 1 ATOM 1699 N N . THR A 1 218 ? -3.420 -15.254 43.496 1.00 13.67 ? 218 THR A N 1 ATOM 1700 C CA . THR A 1 218 ? -3.781 -16.035 44.651 1.00 14.68 ? 218 THR A CA 1 ATOM 1701 C C . THR A 1 218 ? -5.044 -15.527 45.343 1.00 14.13 ? 218 THR A C 1 ATOM 1702 O O . THR A 1 218 ? -5.486 -16.124 46.318 1.00 17.32 ? 218 THR A O 1 ATOM 1703 C CB . THR A 1 218 ? -2.674 -16.024 45.704 1.00 15.20 ? 218 THR A CB 1 ATOM 1704 O OG1 . THR A 1 218 ? -2.459 -14.682 46.128 1.00 17.75 ? 218 THR A OG1 1 ATOM 1705 C CG2 . THR A 1 218 ? -1.341 -16.541 45.102 1.00 13.82 ? 218 THR A CG2 1 ATOM 1706 N N . PHE A 1 219 ? -5.602 -14.423 44.864 1.00 14.17 ? 219 PHE A N 1 ATOM 1707 C CA . PHE A 1 219 ? -6.788 -13.858 45.491 1.00 12.11 ? 219 PHE A CA 1 ATOM 1708 C C . PHE A 1 219 ? -8.053 -14.719 45.246 1.00 13.74 ? 219 PHE A C 1 ATOM 1709 O O . PHE A 1 219 ? -8.270 -15.229 44.139 1.00 13.85 ? 219 PHE A O 1 ATOM 1710 C CB . PHE A 1 219 ? -7.024 -12.461 44.941 1.00 12.78 ? 219 PHE A CB 1 ATOM 1711 C CG . PHE A 1 219 ? -8.323 -11.808 45.455 1.00 12.94 ? 219 PHE A CG 1 ATOM 1712 C CD1 . PHE A 1 219 ? -8.389 -11.325 46.752 1.00 13.02 ? 219 PHE A CD1 1 ATOM 1713 C CD2 . PHE A 1 219 ? -9.445 -11.714 44.633 1.00 14.20 ? 219 PHE A CD2 1 ATOM 1714 C CE1 . PHE A 1 219 ? -9.606 -10.748 47.254 1.00 13.31 ? 219 PHE A CE1 1 ATOM 1715 C CE2 . PHE A 1 219 ? -10.624 -11.123 45.099 1.00 13.84 ? 219 PHE A CE2 1 ATOM 1716 C CZ . PHE A 1 219 ? -10.699 -10.628 46.398 1.00 12.74 ? 219 PHE A CZ 1 ATOM 1717 N N . PHE A 1 220 ? -8.896 -14.824 46.277 1.00 13.83 ? 220 PHE A N 1 ATOM 1718 C CA . PHE A 1 220 ? -10.244 -15.352 46.125 1.00 14.26 ? 220 PHE A CA 1 ATOM 1719 C C . PHE A 1 220 ? -11.207 -14.541 46.977 1.00 13.18 ? 220 PHE A C 1 ATOM 1720 O O . PHE A 1 220 ? -10.816 -13.951 47.958 1.00 12.82 ? 220 PHE A O 1 ATOM 1721 C CB . PHE A 1 220 ? -10.359 -16.855 46.438 1.00 15.77 ? 220 PHE A CB 1 ATOM 1722 C CG . PHE A 1 220 ? -10.275 -17.201 47.911 1.00 16.66 ? 220 PHE A CG 1 ATOM 1723 C CD1 . PHE A 1 220 ? -11.406 -17.183 48.718 1.00 14.82 ? 220 PHE A CD1 1 ATOM 1724 C CD2 . PHE A 1 220 ? -9.044 -17.551 48.484 1.00 16.22 ? 220 PHE A CD2 1 ATOM 1725 C CE1 . PHE A 1 220 ? -11.335 -17.484 50.072 1.00 18.84 ? 220 PHE A CE1 1 ATOM 1726 C CE2 . PHE A 1 220 ? -8.967 -17.852 49.860 1.00 16.75 ? 220 PHE A CE2 1 ATOM 1727 C CZ . PHE A 1 220 ? -10.115 -17.828 50.641 1.00 18.66 ? 220 PHE A CZ 1 ATOM 1728 N N . LEU A 1 221 ? -12.475 -14.579 46.586 1.00 13.43 ? 221 LEU A N 1 ATOM 1729 C CA . LEU A 1 221 ? -13.531 -13.859 47.244 1.00 13.70 ? 221 LEU A CA 1 ATOM 1730 C C . LEU A 1 221 ? -14.527 -14.945 47.628 1.00 13.59 ? 221 LEU A C 1 ATOM 1731 O O . LEU A 1 221 ? -14.777 -15.860 46.851 1.00 13.43 ? 221 LEU A O 1 ATOM 1732 C CB . LEU A 1 221 ? -14.201 -12.911 46.236 1.00 12.90 ? 221 LEU A CB 1 ATOM 1733 C CG . LEU A 1 221 ? -15.315 -11.980 46.670 1.00 15.06 ? 221 LEU A CG 1 ATOM 1734 C CD1 . LEU A 1 221 ? -15.188 -10.762 45.816 1.00 15.08 ? 221 LEU A CD1 1 ATOM 1735 C CD2 . LEU A 1 221 ? -16.671 -12.671 46.418 1.00 17.47 ? 221 LEU A CD2 1 ATOM 1736 N N . CYS A 1 222 ? -15.119 -14.792 48.808 1.00 14.80 ? 222 CYS A N 1 ATOM 1737 C CA . CYS A 1 222 ? -16.164 -15.682 49.303 1.00 15.44 ? 222 CYS A CA 1 ATOM 1738 C C . CYS A 1 222 ? -17.405 -14.867 49.661 1.00 14.93 ? 222 CYS A C 1 ATOM 1739 O O . CYS A 1 222 ? -17.325 -13.960 50.482 1.00 14.03 ? 222 CYS A O 1 ATOM 1740 C CB . CYS A 1 222 ? -15.643 -16.382 50.542 1.00 16.65 ? 222 CYS A CB 1 ATOM 1741 S SG . CYS A 1 222 ? -16.863 -17.492 51.286 1.00 18.64 ? 222 CYS A SG 1 ATOM 1742 N N . LEU A 1 223 ? -18.536 -15.202 49.050 1.00 15.23 ? 223 LEU A N 1 ATOM 1743 C CA . LEU A 1 223 ? -19.832 -14.616 49.414 1.00 15.44 ? 223 LEU A CA 1 ATOM 1744 C C . LEU A 1 223 ? -20.395 -15.484 50.556 1.00 15.68 ? 223 LEU A C 1 ATOM 1745 O O . LEU A 1 223 ? -20.722 -16.664 50.362 1.00 16.27 ? 223 LEU A O 1 ATOM 1746 C CB . LEU A 1 223 ? -20.796 -14.622 48.205 1.00 14.92 ? 223 LEU A CB 1 ATOM 1747 C CG . LEU A 1 223 ? -22.270 -14.268 48.521 1.00 15.45 ? 223 LEU A CG 1 ATOM 1748 C CD1 . LEU A 1 223 ? -22.426 -12.806 48.976 1.00 15.36 ? 223 LEU A CD1 1 ATOM 1749 C CD2 . LEU A 1 223 ? -23.147 -14.531 47.328 1.00 15.63 ? 223 LEU A CD2 1 ATOM 1750 N N . GLU A 1 224 ? -20.497 -14.891 51.736 1.00 15.95 ? 224 GLU A N 1 ATOM 1751 C CA . GLU A 1 224 ? -20.825 -15.640 52.964 1.00 16.90 ? 224 GLU A CA 1 ATOM 1752 C C . GLU A 1 224 ? -22.275 -16.096 52.964 1.00 17.72 ? 224 GLU A C 1 ATOM 1753 O O . GLU A 1 224 ? -22.571 -17.220 53.330 1.00 17.76 ? 224 GLU A O 1 ATOM 1754 C CB . GLU A 1 224 ? -20.537 -14.789 54.201 1.00 17.05 ? 224 GLU A CB 1 ATOM 1755 C CG . GLU A 1 224 ? -19.054 -14.374 54.326 1.00 19.41 ? 224 GLU A CG 1 ATOM 1756 C CD . GLU A 1 224 ? -18.860 -13.156 55.223 1.00 21.13 ? 224 GLU A CD 1 ATOM 1757 O OE1 . GLU A 1 224 ? -19.515 -13.033 56.301 1.00 21.96 ? 224 GLU A OE1 1 ATOM 1758 O OE2 . GLU A 1 224 ? -17.997 -12.348 54.870 1.00 23.62 ? 224 GLU A OE2 1 ATOM 1759 N N . ASP A 1 225 ? -23.176 -15.230 52.531 1.00 19.35 ? 225 ASP A N 1 ATOM 1760 C CA . ASP A 1 225 ? -24.608 -15.575 52.535 1.00 19.91 ? 225 ASP A CA 1 ATOM 1761 C C . ASP A 1 225 ? -25.405 -14.577 51.698 1.00 19.97 ? 225 ASP A C 1 ATOM 1762 O O . ASP A 1 225 ? -24.848 -13.598 51.153 1.00 18.67 ? 225 ASP A O 1 ATOM 1763 C CB . ASP A 1 225 ? -25.147 -15.633 53.996 1.00 21.42 ? 225 ASP A CB 1 ATOM 1764 C CG . ASP A 1 225 ? -24.960 -14.338 54.770 1.00 24.07 ? 225 ASP A CG 1 ATOM 1765 O OD1 . ASP A 1 225 ? -25.433 -13.257 54.317 1.00 28.20 ? 225 ASP A OD1 1 ATOM 1766 O OD2 . ASP A 1 225 ? -24.390 -14.367 55.893 1.00 31.29 ? 225 ASP A OD2 1 ATOM 1767 N N . ALA A 1 226 ? -26.718 -14.803 51.615 1.00 18.74 ? 226 ALA A N 1 ATOM 1768 C CA . ALA A 1 226 ? -27.572 -13.948 50.781 1.00 18.40 ? 226 ALA A CA 1 ATOM 1769 C C . ALA A 1 226 ? -27.668 -12.480 51.241 1.00 18.59 ? 226 ALA A C 1 ATOM 1770 O O . ALA A 1 226 ? -28.215 -11.658 50.529 1.00 19.64 ? 226 ALA A O 1 ATOM 1771 C CB . ALA A 1 226 ? -28.986 -14.589 50.646 1.00 18.82 ? 226 ALA A CB 1 ATOM 1772 N N . SER A 1 227 ? -27.121 -12.114 52.402 1.00 17.18 ? 227 SER A N 1 ATOM 1773 C CA . SER A 1 227 ? -27.116 -10.714 52.803 1.00 18.64 ? 227 SER A CA 1 ATOM 1774 C C . SER A 1 227 ? -26.151 -9.910 51.963 1.00 18.51 ? 227 SER A C 1 ATOM 1775 O O . SER A 1 227 ? -26.272 -8.691 51.895 1.00 17.15 ? 227 SER A O 1 ATOM 1776 C CB . SER A 1 227 ? -26.743 -10.515 54.280 1.00 18.50 ? 227 SER A CB 1 ATOM 1777 O OG . SER A 1 227 ? -25.428 -11.005 54.509 1.00 24.10 ? 227 SER A OG 1 ATOM 1778 N N . GLY A 1 228 ? -25.197 -10.606 51.334 1.00 16.63 ? 228 GLY A N 1 ATOM 1779 C CA . GLY A 1 228 ? -24.157 -9.924 50.553 1.00 15.22 ? 228 GLY A CA 1 ATOM 1780 C C . GLY A 1 228 ? -22.822 -9.918 51.260 1.00 14.69 ? 228 GLY A C 1 ATOM 1781 O O . GLY A 1 228 ? -21.802 -9.702 50.611 1.00 12.17 ? 228 GLY A O 1 ATOM 1782 N N . LEU A 1 229 ? -22.818 -10.160 52.580 1.00 13.83 ? 229 LEU A N 1 ATOM 1783 C CA . LEU A 1 229 ? -21.583 -10.064 53.370 1.00 13.77 ? 229 LEU A CA 1 ATOM 1784 C C . LEU A 1 229 ? -20.532 -10.979 52.714 1.00 12.99 ? 229 LEU A C 1 ATOM 1785 O O . LEU A 1 229 ? -20.840 -12.111 52.385 1.00 12.81 ? 229 LEU A O 1 ATOM 1786 C CB . LEU A 1 229 ? -21.822 -10.502 54.812 1.00 14.63 ? 229 LEU A CB 1 ATOM 1787 C CG . LEU A 1 229 ? -22.720 -9.558 55.637 1.00 15.05 ? 229 LEU A CG 1 ATOM 1788 C CD1 . LEU A 1 229 ? -22.964 -10.054 57.037 1.00 19.59 ? 229 LEU A CD1 1 ATOM 1789 C CD2 . LEU A 1 229 ? -22.216 -8.142 55.613 1.00 15.47 ? 229 LEU A CD2 1 ATOM 1790 N N . SER A 1 230 ? -19.323 -10.472 52.492 1.00 14.28 ? 230 SER A N 1 ATOM 1791 C CA . SER A 1 230 ? -18.343 -11.236 51.696 1.00 13.29 ? 230 SER A CA 1 ATOM 1792 C C . SER A 1 230 ? -16.977 -10.929 52.275 1.00 12.86 ? 230 SER A C 1 ATOM 1793 O O . SER A 1 230 ? -16.813 -9.944 52.959 1.00 10.58 ? 230 SER A O 1 ATOM 1794 C CB . SER A 1 230 ? -18.348 -10.783 50.225 1.00 13.61 ? 230 SER A CB 1 ATOM 1795 O OG . SER A 1 230 ? -19.612 -10.994 49.582 1.00 14.57 ? 230 SER A OG 1 ATOM 1796 N N . PHE A 1 231 ? -15.983 -11.771 51.968 1.00 12.57 ? 231 PHE A N 1 ATOM 1797 C CA . PHE A 1 231 ? -14.605 -11.431 52.407 1.00 12.33 ? 231 PHE A CA 1 ATOM 1798 C C . PHE A 1 231 ? -13.665 -11.994 51.353 1.00 12.65 ? 231 PHE A C 1 ATOM 1799 O O . PHE A 1 231 ? -14.109 -12.717 50.463 1.00 12.78 ? 231 PHE A O 1 ATOM 1800 C CB . PHE A 1 231 ? -14.309 -11.985 53.806 1.00 14.41 ? 231 PHE A CB 1 ATOM 1801 C CG . PHE A 1 231 ? -14.045 -13.461 53.847 1.00 15.14 ? 231 PHE A CG 1 ATOM 1802 C CD1 . PHE A 1 231 ? -12.729 -13.931 53.925 1.00 17.50 ? 231 PHE A CD1 1 ATOM 1803 C CD2 . PHE A 1 231 ? -15.103 -14.393 53.815 1.00 15.68 ? 231 PHE A CD2 1 ATOM 1804 C CE1 . PHE A 1 231 ? -12.460 -15.299 53.966 1.00 18.00 ? 231 PHE A CE1 1 ATOM 1805 C CE2 . PHE A 1 231 ? -14.836 -15.762 53.882 1.00 17.20 ? 231 PHE A CE2 1 ATOM 1806 C CZ . PHE A 1 231 ? -13.511 -16.225 53.939 1.00 16.31 ? 231 PHE A CZ 1 ATOM 1807 N N . GLY A 1 232 ? -12.380 -11.640 51.435 1.00 12.72 ? 232 GLY A N 1 ATOM 1808 C CA . GLY A 1 232 ? -11.446 -12.068 50.420 1.00 11.36 ? 232 GLY A CA 1 ATOM 1809 C C . GLY A 1 232 ? -10.124 -12.360 51.110 1.00 10.44 ? 232 GLY A C 1 ATOM 1810 O O . GLY A 1 232 ? -9.931 -11.980 52.253 1.00 11.72 ? 232 GLY A O 1 ATOM 1811 N N . VAL A 1 233 ? -9.281 -13.113 50.446 1.00 10.60 ? 233 VAL A N 1 ATOM 1812 C CA . VAL A 1 233 ? -7.959 -13.503 51.030 1.00 10.91 ? 233 VAL A CA 1 ATOM 1813 C C . VAL A 1 233 ? -6.953 -13.372 49.905 1.00 11.36 ? 233 VAL A C 1 ATOM 1814 O O . VAL A 1 233 ? -7.228 -13.783 48.779 1.00 10.86 ? 233 VAL A O 1 ATOM 1815 C CB . VAL A 1 233 ? -7.955 -14.964 51.611 1.00 11.88 ? 233 VAL A CB 1 ATOM 1816 C CG1 . VAL A 1 233 ? -6.507 -15.412 52.004 1.00 12.65 ? 233 VAL A CG1 1 ATOM 1817 C CG2 . VAL A 1 233 ? -8.921 -15.128 52.849 1.00 13.86 ? 233 VAL A CG2 1 ATOM 1818 N N . PHE A 1 234 ? -5.794 -12.767 50.198 1.00 11.07 ? 234 PHE A N 1 ATOM 1819 C CA . PHE A 1 234 ? -4.761 -12.689 49.207 1.00 12.18 ? 234 PHE A CA 1 ATOM 1820 C C . PHE A 1 234 ? -3.491 -13.195 49.922 1.00 12.67 ? 234 PHE A C 1 ATOM 1821 O O . PHE A 1 234 ? -3.279 -12.890 51.096 1.00 11.73 ? 234 PHE A O 1 ATOM 1822 C CB . PHE A 1 234 ? -4.595 -11.240 48.758 1.00 13.67 ? 234 PHE A CB 1 ATOM 1823 C CG . PHE A 1 234 ? -3.353 -11.001 47.979 1.00 10.16 ? 234 PHE A CG 1 ATOM 1824 C CD1 . PHE A 1 234 ? -3.160 -11.640 46.731 1.00 11.11 ? 234 PHE A CD1 1 ATOM 1825 C CD2 . PHE A 1 234 ? -2.411 -10.107 48.441 1.00 13.57 ? 234 PHE A CD2 1 ATOM 1826 C CE1 . PHE A 1 234 ? -1.989 -11.442 45.990 1.00 16.15 ? 234 PHE A CE1 1 ATOM 1827 C CE2 . PHE A 1 234 ? -1.231 -9.868 47.681 1.00 15.57 ? 234 PHE A CE2 1 ATOM 1828 C CZ . PHE A 1 234 ? -1.024 -10.552 46.487 1.00 14.00 ? 234 PHE A CZ 1 ATOM 1829 N N . LEU A 1 235 ? -2.716 -14.013 49.209 1.00 13.13 ? 235 LEU A N 1 ATOM 1830 C CA . LEU A 1 235 ? -1.416 -14.466 49.673 1.00 13.17 ? 235 LEU A CA 1 ATOM 1831 C C . LEU A 1 235 ? -0.308 -13.762 48.844 1.00 11.99 ? 235 LEU A C 1 ATOM 1832 O O . LEU A 1 235 ? -0.226 -13.913 47.627 1.00 12.40 ? 235 LEU A O 1 ATOM 1833 C CB . LEU A 1 235 ? -1.340 -15.994 49.552 1.00 13.13 ? 235 LEU A CB 1 ATOM 1834 C CG . LEU A 1 235 ? 0.063 -16.620 49.746 1.00 14.84 ? 235 LEU A CG 1 ATOM 1835 C CD1 . LEU A 1 235 ? 0.632 -16.225 51.109 1.00 13.34 ? 235 LEU A CD1 1 ATOM 1836 C CD2 . LEU A 1 235 ? -0.107 -18.153 49.612 1.00 15.66 ? 235 LEU A CD2 1 ATOM 1837 N N . MET A 1 236 ? 0.503 -12.941 49.488 1.00 12.23 ? 236 MET A N 1 ATOM 1838 C CA . MET A 1 236 ? 1.577 -12.246 48.788 1.00 13.12 ? 236 MET A CA 1 ATOM 1839 C C . MET A 1 236 ? 2.769 -13.201 48.784 1.00 14.40 ? 236 MET A C 1 ATOM 1840 O O . MET A 1 236 ? 3.609 -13.152 49.702 1.00 13.93 ? 236 MET A O 1 ATOM 1841 C CB . MET A 1 236 ? 2.006 -10.985 49.565 1.00 12.99 ? 236 MET A CB 1 ATOM 1842 C CG . MET A 1 236 ? 3.089 -10.122 48.818 1.00 15.80 ? 236 MET A CG 1 ATOM 1843 S SD . MET A 1 236 ? 2.677 -9.411 47.211 1.00 21.12 ? 236 MET A SD 1 ATOM 1844 C CE . MET A 1 236 ? 2.059 -7.794 47.725 1.00 19.41 ? 236 MET A CE 1 ATOM 1845 N N . ASN A 1 237 ? 2.839 -14.047 47.760 1.00 15.06 ? 237 ASN A N 1 ATOM 1846 C CA . ASN A 1 237 ? 3.945 -15.047 47.619 1.00 14.26 ? 237 ASN A CA 1 ATOM 1847 C C . ASN A 1 237 ? 4.048 -15.343 46.115 1.00 14.74 ? 237 ASN A C 1 ATOM 1848 O O . ASN A 1 237 ? 3.030 -15.557 45.434 1.00 13.59 ? 237 ASN A O 1 ATOM 1849 C CB . ASN A 1 237 ? 3.633 -16.285 48.513 1.00 13.09 ? 237 ASN A CB 1 ATOM 1850 C CG . ASN A 1 237 ? 4.697 -17.400 48.429 1.00 15.11 ? 237 ASN A CG 1 ATOM 1851 O OD1 . ASN A 1 237 ? 4.807 -18.069 47.414 1.00 14.53 ? 237 ASN A OD1 1 ATOM 1852 N ND2 . ASN A 1 237 ? 5.370 -17.671 49.550 1.00 14.79 ? 237 ASN A ND2 1 ATOM 1853 N N . SER A 1 238 ? 5.276 -15.282 45.576 1.00 13.87 ? 238 SER A N 1 ATOM 1854 C CA . SER A 1 238 ? 5.512 -15.566 44.168 1.00 15.37 ? 238 SER A CA 1 ATOM 1855 C C . SER A 1 238 ? 6.229 -16.914 43.812 1.00 15.70 ? 238 SER A C 1 ATOM 1856 O O . SER A 1 238 ? 6.682 -17.079 42.679 1.00 15.86 ? 238 SER A O 1 ATOM 1857 C CB . SER A 1 238 ? 6.350 -14.411 43.585 1.00 15.72 ? 238 SER A CB 1 ATOM 1858 O OG . SER A 1 238 ? 7.524 -14.251 44.344 1.00 15.63 ? 238 SER A OG 1 ATOM 1859 N N . ASN A 1 239 ? 6.375 -17.815 44.778 1.00 16.22 ? 239 ASN A N 1 ATOM 1860 C CA . ASN A 1 239 ? 6.936 -19.153 44.533 1.00 16.77 ? 239 ASN A CA 1 ATOM 1861 C C . ASN A 1 239 ? 5.897 -20.046 43.894 1.00 16.61 ? 239 ASN A C 1 ATOM 1862 O O . ASN A 1 239 ? 4.675 -19.709 43.918 1.00 15.55 ? 239 ASN A O 1 ATOM 1863 C CB . ASN A 1 239 ? 7.494 -19.762 45.829 1.00 16.89 ? 239 ASN A CB 1 ATOM 1864 C CG . ASN A 1 239 ? 8.720 -19.015 46.329 1.00 17.18 ? 239 ASN A CG 1 ATOM 1865 O OD1 . ASN A 1 239 ? 9.888 -19.387 46.030 1.00 21.54 ? 239 ASN A OD1 1 ATOM 1866 N ND2 . ASN A 1 239 ? 8.486 -17.952 47.067 1.00 16.26 ? 239 ASN A ND2 1 ATOM 1867 N N . ALA A 1 240 ? 6.348 -21.127 43.252 1.00 14.29 ? 240 ALA A N 1 ATOM 1868 C CA . ALA A 1 240 ? 5.402 -22.165 42.780 1.00 15.18 ? 240 ALA A CA 1 ATOM 1869 C C . ALA A 1 240 ? 4.515 -22.602 43.914 1.00 14.90 ? 240 ALA A C 1 ATOM 1870 O O . ALA A 1 240 ? 4.976 -22.794 45.016 1.00 14.26 ? 240 ALA A O 1 ATOM 1871 C CB . ALA A 1 240 ? 6.156 -23.389 42.193 1.00 15.88 ? 240 ALA A CB 1 ATOM 1872 N N . MET A 1 241 ? 3.209 -22.726 43.669 1.00 14.60 ? 241 MET A N 1 ATOM 1873 C CA . MET A 1 241 ? 2.352 -23.133 44.755 1.00 15.17 ? 241 MET A CA 1 ATOM 1874 C C . MET A 1 241 ? 1.164 -23.888 44.167 1.00 14.57 ? 241 MET A C 1 ATOM 1875 O O . MET A 1 241 ? 0.994 -23.963 42.940 1.00 13.70 ? 241 MET A O 1 ATOM 1876 C CB . MET A 1 241 ? 1.867 -21.900 45.547 1.00 16.18 ? 241 MET A CB 1 ATOM 1877 C CG . MET A 1 241 ? 0.875 -21.079 44.781 1.00 15.66 ? 241 MET A CG 1 ATOM 1878 S SD . MET A 1 241 ? 0.149 -19.846 45.883 1.00 19.96 ? 241 MET A SD 1 ATOM 1879 C CE . MET A 1 241 ? 1.519 -18.707 45.960 1.00 15.64 ? 241 MET A CE 1 ATOM 1880 N N . GLU A 1 242 ? 0.373 -24.482 45.034 1.00 14.97 ? 242 GLU A N 1 ATOM 1881 C CA . GLU A 1 242 ? -0.933 -24.983 44.601 1.00 16.47 ? 242 GLU A CA 1 ATOM 1882 C C . GLU A 1 242 ? -1.958 -24.704 45.674 1.00 16.15 ? 242 GLU A C 1 ATOM 1883 O O . GLU A 1 242 ? -1.628 -24.564 46.857 1.00 15.94 ? 242 GLU A O 1 ATOM 1884 C CB . GLU A 1 242 ? -0.896 -26.470 44.240 1.00 17.16 ? 242 GLU A CB 1 ATOM 1885 C CG . GLU A 1 242 ? -0.416 -27.392 45.347 1.00 18.90 ? 242 GLU A CG 1 ATOM 1886 C CD . GLU A 1 242 ? -0.037 -28.769 44.820 1.00 22.09 ? 242 GLU A CD 1 ATOM 1887 O OE1 . GLU A 1 242 ? 0.185 -28.933 43.593 1.00 22.28 ? 242 GLU A OE1 1 ATOM 1888 O OE2 . GLU A 1 242 ? 0.051 -29.694 45.633 1.00 24.05 ? 242 GLU A OE2 1 ATOM 1889 N N . VAL A 1 243 ? -3.225 -24.648 45.276 1.00 16.23 ? 243 VAL A N 1 ATOM 1890 C CA . VAL A 1 243 ? -4.240 -24.308 46.229 1.00 14.90 ? 243 VAL A CA 1 ATOM 1891 C C . VAL A 1 243 ? -5.197 -25.512 46.210 1.00 15.36 ? 243 VAL A C 1 ATOM 1892 O O . VAL A 1 243 ? -5.524 -26.000 45.140 1.00 14.12 ? 243 VAL A O 1 ATOM 1893 C CB . VAL A 1 243 ? -4.938 -23.002 45.792 1.00 15.86 ? 243 VAL A CB 1 ATOM 1894 C CG1 . VAL A 1 243 ? -6.067 -22.693 46.690 1.00 15.00 ? 243 VAL A CG1 1 ATOM 1895 C CG2 . VAL A 1 243 ? -3.911 -21.819 45.724 1.00 16.96 ? 243 VAL A CG2 1 ATOM 1896 N N . VAL A 1 244 ? -5.583 -26.000 47.388 1.00 14.36 ? 244 VAL A N 1 ATOM 1897 C CA . VAL A 1 244 ? -6.307 -27.255 47.511 1.00 15.52 ? 244 VAL A CA 1 ATOM 1898 C C . VAL A 1 244 ? -7.671 -26.907 48.074 1.00 15.11 ? 244 VAL A C 1 ATOM 1899 O O . VAL A 1 244 ? -7.769 -26.354 49.154 1.00 14.78 ? 244 VAL A O 1 ATOM 1900 C CB . VAL A 1 244 ? -5.569 -28.255 48.419 1.00 15.80 ? 244 VAL A CB 1 ATOM 1901 C CG1 . VAL A 1 244 ? -6.336 -29.594 48.571 1.00 16.49 ? 244 VAL A CG1 1 ATOM 1902 C CG2 . VAL A 1 244 ? -4.187 -28.525 47.840 1.00 17.47 ? 244 VAL A CG2 1 ATOM 1903 N N . LEU A 1 245 ? -8.713 -27.254 47.341 1.00 16.33 ? 245 LEU A N 1 ATOM 1904 C CA . LEU A 1 245 ? -10.068 -26.920 47.750 1.00 16.56 ? 245 LEU A CA 1 ATOM 1905 C C . LEU A 1 245 ? -10.750 -28.196 48.169 1.00 16.63 ? 245 LEU A C 1 ATOM 1906 O O . LEU A 1 245 ? -10.570 -29.234 47.521 1.00 18.02 ? 245 LEU A O 1 ATOM 1907 C CB . LEU A 1 245 ? -10.840 -26.246 46.591 1.00 17.07 ? 245 LEU A CB 1 ATOM 1908 C CG . LEU A 1 245 ? -10.167 -25.121 45.776 1.00 20.77 ? 245 LEU A CG 1 ATOM 1909 C CD1 . LEU A 1 245 ? -11.185 -24.651 44.782 1.00 22.65 ? 245 LEU A CD1 1 ATOM 1910 C CD2 . LEU A 1 245 ? -9.850 -24.005 46.656 1.00 22.37 ? 245 LEU A CD2 1 ATOM 1911 N N . GLN A 1 246 ? -11.476 -28.163 49.283 1.00 15.87 ? 246 GLN A N 1 ATOM 1912 C CA . GLN A 1 246 ? -12.168 -29.381 49.731 1.00 15.86 ? 246 GLN A CA 1 ATOM 1913 C C . GLN A 1 246 ? -13.513 -29.043 50.332 1.00 16.83 ? 246 GLN A C 1 ATOM 1914 O O . GLN A 1 246 ? -13.740 -27.885 50.690 1.00 15.69 ? 246 GLN A O 1 ATOM 1915 C CB . GLN A 1 246 ? -11.341 -30.173 50.714 1.00 16.78 ? 246 GLN A CB 1 ATOM 1916 C CG . GLN A 1 246 ? -11.115 -29.540 52.072 1.00 15.30 ? 246 GLN A CG 1 ATOM 1917 C CD . GLN A 1 246 ? -10.047 -30.315 52.813 1.00 18.95 ? 246 GLN A CD 1 ATOM 1918 O OE1 . GLN A 1 246 ? -8.863 -30.178 52.508 1.00 16.30 ? 246 GLN A OE1 1 ATOM 1919 N NE2 . GLN A 1 246 ? -10.453 -31.127 53.780 1.00 18.04 ? 246 GLN A NE2 1 ATOM 1920 N N . PRO A 1 247 ? -14.414 -30.045 50.405 1.00 17.45 ? 247 PRO A N 1 ATOM 1921 C CA . PRO A 1 247 ? -15.826 -29.767 50.716 1.00 18.50 ? 247 PRO A CA 1 ATOM 1922 C C . PRO A 1 247 ? -16.147 -29.470 52.165 1.00 19.13 ? 247 PRO A C 1 ATOM 1923 O O . PRO A 1 247 ? -17.314 -29.281 52.472 1.00 20.48 ? 247 PRO A O 1 ATOM 1924 C CB . PRO A 1 247 ? -16.551 -31.068 50.324 1.00 18.75 ? 247 PRO A CB 1 ATOM 1925 C CG . PRO A 1 247 ? -15.554 -31.934 49.689 1.00 19.59 ? 247 PRO A CG 1 ATOM 1926 C CD . PRO A 1 247 ? -14.193 -31.456 50.103 1.00 18.76 ? 247 PRO A CD 1 ATOM 1927 N N . ALA A 1 248 ? -15.161 -29.437 53.058 1.00 19.66 ? 248 ALA A N 1 ATOM 1928 C CA . ALA A 1 248 ? -15.381 -28.991 54.452 1.00 19.22 ? 248 ALA A CA 1 ATOM 1929 C C . ALA A 1 248 ? -16.448 -27.877 54.664 1.00 20.96 ? 248 ALA A C 1 ATOM 1930 O O . ALA A 1 248 ? -17.299 -28.019 55.586 1.00 18.77 ? 248 ALA A O 1 ATOM 1931 C CB . ALA A 1 248 ? -14.067 -28.581 55.078 1.00 20.44 ? 248 ALA A CB 1 ATOM 1932 N N . PRO A 1 249 ? -16.363 -26.701 53.895 1.00 18.41 ? 249 PRO A N 1 ATOM 1933 C CA . PRO A 1 249 ? -15.390 -26.292 52.886 1.00 17.77 ? 249 PRO A CA 1 ATOM 1934 C C . PRO A 1 249 ? -14.132 -25.665 53.477 1.00 17.15 ? 249 PRO A C 1 ATOM 1935 O O . PRO A 1 249 ? -14.157 -25.074 54.566 1.00 16.53 ? 249 PRO A O 1 ATOM 1936 C CB . PRO A 1 249 ? -16.156 -25.240 52.080 1.00 18.45 ? 249 PRO A CB 1 ATOM 1937 C CG . PRO A 1 249 ? -16.995 -24.604 53.052 1.00 17.28 ? 249 PRO A CG 1 ATOM 1938 C CD . PRO A 1 249 ? -17.412 -25.675 54.037 1.00 19.32 ? 249 PRO A CD 1 ATOM 1939 N N . ALA A 1 250 ? -13.033 -25.795 52.742 1.00 16.29 ? 250 ALA A N 1 ATOM 1940 C CA . ALA A 1 250 ? -11.754 -25.293 53.231 1.00 15.73 ? 250 ALA A CA 1 ATOM 1941 C C . ALA A 1 250 ? -10.827 -25.135 52.054 1.00 14.43 ? 250 ALA A C 1 ATOM 1942 O O . ALA A 1 250 ? -11.034 -25.754 50.999 1.00 13.17 ? 250 ALA A O 1 ATOM 1943 C CB . ALA A 1 250 ? -11.184 -26.285 54.215 1.00 16.18 ? 250 ALA A CB 1 ATOM 1944 N N . ILE A 1 251 ? -9.808 -24.299 52.238 1.00 14.22 ? 251 ILE A N 1 ATOM 1945 C CA A ILE A 1 251 ? -8.799 -24.073 51.218 0.50 13.88 ? 251 ILE A CA 1 ATOM 1946 C CA B ILE A 1 251 ? -8.780 -24.047 51.221 0.50 14.64 ? 251 ILE A CA 1 ATOM 1947 C C . ILE A 1 251 ? -7.432 -24.174 51.887 1.00 14.83 ? 251 ILE A C 1 ATOM 1948 O O . ILE A 1 251 ? -7.257 -23.753 53.028 1.00 15.10 ? 251 ILE A O 1 ATOM 1949 C CB A ILE A 1 251 ? -9.025 -22.705 50.473 0.50 13.99 ? 251 ILE A CB 1 ATOM 1950 C CB B ILE A 1 251 ? -8.864 -22.619 50.594 0.50 14.64 ? 251 ILE A CB 1 ATOM 1951 C CG1 A ILE A 1 251 ? -8.035 -22.493 49.323 0.50 14.34 ? 251 ILE A CG1 1 ATOM 1952 C CG1 B ILE A 1 251 ? -9.974 -22.546 49.546 0.50 16.08 ? 251 ILE A CG1 1 ATOM 1953 C CG2 A ILE A 1 251 ? -9.026 -21.534 51.434 0.50 13.35 ? 251 ILE A CG2 1 ATOM 1954 C CG2 B ILE A 1 251 ? -7.520 -22.210 49.935 0.50 16.24 ? 251 ILE A CG2 1 ATOM 1955 C CD1 A ILE A 1 251 ? -8.318 -21.258 48.488 0.50 13.42 ? 251 ILE A CD1 1 ATOM 1956 C CD1 B ILE A 1 251 ? -10.110 -21.184 48.901 0.50 15.22 ? 251 ILE A CD1 1 ATOM 1957 N N . THR A 1 252 ? -6.492 -24.768 51.177 1.00 14.03 ? 252 THR A N 1 ATOM 1958 C CA . THR A 1 252 ? -5.140 -24.904 51.689 1.00 15.27 ? 252 THR A CA 1 ATOM 1959 C C . THR A 1 252 ? -4.227 -24.263 50.651 1.00 14.98 ? 252 THR A C 1 ATOM 1960 O O . THR A 1 252 ? -4.388 -24.508 49.451 1.00 14.47 ? 252 THR A O 1 ATOM 1961 C CB . THR A 1 252 ? -4.826 -26.404 51.881 1.00 15.80 ? 252 THR A CB 1 ATOM 1962 O OG1 . THR A 1 252 ? -5.690 -26.946 52.905 1.00 16.57 ? 252 THR A OG1 1 ATOM 1963 C CG2 . THR A 1 252 ? -3.367 -26.633 52.291 1.00 16.91 ? 252 THR A CG2 1 ATOM 1964 N N . TYR A 1 253 ? -3.262 -23.452 51.106 1.00 14.14 ? 253 TYR A N 1 ATOM 1965 C CA . TYR A 1 253 ? -2.258 -22.896 50.234 1.00 14.27 ? 253 TYR A CA 1 ATOM 1966 C C . TYR A 1 253 ? -0.983 -23.686 50.545 1.00 14.42 ? 253 TYR A C 1 ATOM 1967 O O . TYR A 1 253 ? -0.643 -23.881 51.715 1.00 14.19 ? 253 TYR A O 1 ATOM 1968 C CB . TYR A 1 253 ? -1.999 -21.442 50.603 1.00 16.24 ? 253 TYR A CB 1 ATOM 1969 C CG . TYR A 1 253 ? -3.047 -20.437 50.108 1.00 16.94 ? 253 TYR A CG 1 ATOM 1970 C CD1 . TYR A 1 253 ? -2.968 -19.929 48.827 1.00 18.28 ? 253 TYR A CD1 1 ATOM 1971 C CD2 . TYR A 1 253 ? -4.103 -20.018 50.927 1.00 22.25 ? 253 TYR A CD2 1 ATOM 1972 C CE1 . TYR A 1 253 ? -3.893 -18.977 48.337 1.00 21.30 ? 253 TYR A CE1 1 ATOM 1973 C CE2 . TYR A 1 253 ? -5.051 -19.073 50.442 1.00 19.14 ? 253 TYR A CE2 1 ATOM 1974 C CZ . TYR A 1 253 ? -4.930 -18.576 49.159 1.00 21.25 ? 253 TYR A CZ 1 ATOM 1975 O OH . TYR A 1 253 ? -5.844 -17.640 48.679 1.00 22.48 ? 253 TYR A OH 1 ATOM 1976 N N . ARG A 1 254 ? -0.293 -24.090 49.503 1.00 14.52 ? 254 ARG A N 1 ATOM 1977 C CA A ARG A 1 254 ? 0.906 -24.919 49.625 0.50 16.03 ? 254 ARG A CA 1 ATOM 1978 C CA B ARG A 1 254 ? 0.912 -24.908 49.649 0.50 15.14 ? 254 ARG A CA 1 ATOM 1979 C C . ARG A 1 254 ? 1.952 -24.297 48.728 1.00 15.58 ? 254 ARG A C 1 ATOM 1980 O O . ARG A 1 254 ? 1.837 -24.403 47.528 1.00 17.73 ? 254 ARG A O 1 ATOM 1981 C CB A ARG A 1 254 ? 0.549 -26.309 49.098 0.50 16.86 ? 254 ARG A CB 1 ATOM 1982 C CB B ARG A 1 254 ? 0.536 -26.326 49.219 0.50 15.53 ? 254 ARG A CB 1 ATOM 1983 C CG A ARG A 1 254 ? 1.053 -27.440 49.945 0.50 19.43 ? 254 ARG A CG 1 ATOM 1984 C CG B ARG A 1 254 ? 1.495 -27.435 49.586 0.50 13.70 ? 254 ARG A CG 1 ATOM 1985 C CD A ARG A 1 254 ? 1.228 -28.727 49.162 0.50 22.36 ? 254 ARG A CD 1 ATOM 1986 C CD B ARG A 1 254 ? 0.911 -28.735 49.045 0.50 12.31 ? 254 ARG A CD 1 ATOM 1987 N NE A ARG A 1 254 ? 0.032 -29.223 48.483 0.50 23.71 ? 254 ARG A NE 1 ATOM 1988 N NE B ARG A 1 254 ? -0.185 -29.355 49.799 0.50 6.95 ? 254 ARG A NE 1 ATOM 1989 C CZ A ARG A 1 254 ? -1.010 -29.787 49.086 0.50 23.29 ? 254 ARG A CZ 1 ATOM 1990 C CZ B ARG A 1 254 ? -1.066 -30.198 49.245 0.50 7.88 ? 254 ARG A CZ 1 ATOM 1991 N NH1 A ARG A 1 254 ? -1.048 -29.910 50.400 0.50 21.87 ? 254 ARG A NH1 1 ATOM 1992 N NH1 B ARG A 1 254 ? -0.995 -30.450 47.932 0.50 8.92 ? 254 ARG A NH1 1 ATOM 1993 N NH2 A ARG A 1 254 ? -2.020 -30.229 48.358 0.50 23.74 ? 254 ARG A NH2 1 ATOM 1994 N NH2 B ARG A 1 254 ? -2.013 -30.792 49.965 0.50 6.65 ? 254 ARG A NH2 1 ATOM 1995 N N . THR A 1 255 ? 2.961 -23.626 49.278 1.00 15.85 ? 255 THR A N 1 ATOM 1996 C CA . THR A 1 255 ? 3.952 -22.977 48.426 1.00 15.43 ? 255 THR A CA 1 ATOM 1997 C C . THR A 1 255 ? 5.365 -23.533 48.722 1.00 15.68 ? 255 THR A C 1 ATOM 1998 O O . THR A 1 255 ? 5.617 -24.068 49.803 1.00 15.37 ? 255 THR A O 1 ATOM 1999 C CB . THR A 1 255 ? 3.923 -21.444 48.565 1.00 15.94 ? 255 THR A CB 1 ATOM 2000 O OG1 . THR A 1 255 ? 4.958 -20.850 47.749 1.00 19.45 ? 255 THR A OG1 1 ATOM 2001 C CG2 . THR A 1 255 ? 4.096 -21.018 50.021 1.00 17.06 ? 255 THR A CG2 1 ATOM 2002 N N . ILE A 1 256 ? 6.282 -23.359 47.779 1.00 15.15 ? 256 ILE A N 1 ATOM 2003 C CA . ILE A 1 256 ? 7.594 -24.000 47.964 1.00 14.96 ? 256 ILE A CA 1 ATOM 2004 C C . ILE A 1 256 ? 8.707 -22.969 48.241 1.00 16.45 ? 256 ILE A C 1 ATOM 2005 O O . ILE A 1 256 ? 9.913 -23.254 48.076 1.00 15.86 ? 256 ILE A O 1 ATOM 2006 C CB . ILE A 1 256 ? 7.950 -24.961 46.807 1.00 15.51 ? 256 ILE A CB 1 ATOM 2007 C CG1 . ILE A 1 256 ? 8.206 -24.201 45.494 1.00 15.01 ? 256 ILE A CG1 1 ATOM 2008 C CG2 . ILE A 1 256 ? 6.898 -26.069 46.668 1.00 16.08 ? 256 ILE A CG2 1 ATOM 2009 C CD1 . ILE A 1 256 ? 8.772 -25.074 44.424 1.00 13.24 ? 256 ILE A CD1 1 ATOM 2010 N N . GLY A 1 257 ? 8.317 -21.774 48.692 1.00 14.98 ? 257 GLY A N 1 ATOM 2011 C CA . GLY A 1 257 ? 9.342 -20.875 49.209 1.00 14.65 ? 257 GLY A CA 1 ATOM 2012 C C . GLY A 1 257 ? 8.747 -19.626 49.759 1.00 15.42 ? 257 GLY A C 1 ATOM 2013 O O . GLY A 1 257 ? 7.524 -19.534 49.913 1.00 15.29 ? 257 GLY A O 1 ATOM 2014 N N . GLY A 1 258 ? 9.617 -18.659 49.992 1.00 13.20 ? 258 GLY A N 1 ATOM 2015 C CA . GLY A 1 258 ? 9.253 -17.370 50.554 1.00 13.83 ? 258 GLY A CA 1 ATOM 2016 C C . GLY A 1 258 ? 8.628 -17.464 51.928 1.00 13.09 ? 258 GLY A C 1 ATOM 2017 O O . GLY A 1 258 ? 9.008 -18.280 52.784 1.00 12.36 ? 258 GLY A O 1 ATOM 2018 N N . ILE A 1 259 ? 7.587 -16.654 52.123 1.00 13.32 ? 259 ILE A N 1 ATOM 2019 C CA . ILE A 1 259 ? 6.976 -16.534 53.439 1.00 15.29 ? 259 ILE A CA 1 ATOM 2020 C C . ILE A 1 259 ? 5.447 -16.584 53.262 1.00 15.34 ? 259 ILE A C 1 ATOM 2021 O O . ILE A 1 259 ? 4.937 -16.373 52.150 1.00 15.35 ? 259 ILE A O 1 ATOM 2022 C CB . ILE A 1 259 ? 7.397 -15.221 54.230 1.00 15.36 ? 259 ILE A CB 1 ATOM 2023 C CG1 . ILE A 1 259 ? 6.923 -13.921 53.524 1.00 14.44 ? 259 ILE A CG1 1 ATOM 2024 C CG2 . ILE A 1 259 ? 8.919 -15.186 54.505 1.00 16.19 ? 259 ILE A CG2 1 ATOM 2025 C CD1 . ILE A 1 259 ? 6.751 -12.698 54.450 1.00 15.91 ? 259 ILE A CD1 1 ATOM 2026 N N . LEU A 1 260 ? 4.733 -16.806 54.362 1.00 15.30 ? 260 LEU A N 1 ATOM 2027 C CA . LEU A 1 260 ? 3.270 -16.774 54.275 1.00 15.94 ? 260 LEU A CA 1 ATOM 2028 C C . LEU A 1 260 ? 2.812 -15.366 54.661 1.00 16.93 ? 260 LEU A C 1 ATOM 2029 O O . LEU A 1 260 ? 2.836 -15.011 55.817 1.00 19.05 ? 260 LEU A O 1 ATOM 2030 C CB . LEU A 1 260 ? 2.652 -17.839 55.156 1.00 15.40 ? 260 LEU A CB 1 ATOM 2031 C CG . LEU A 1 260 ? 2.920 -19.271 54.712 1.00 13.57 ? 260 LEU A CG 1 ATOM 2032 C CD1 . LEU A 1 260 ? 2.419 -20.212 55.755 1.00 17.23 ? 260 LEU A CD1 1 ATOM 2033 C CD2 . LEU A 1 260 ? 2.362 -19.630 53.291 1.00 14.29 ? 260 LEU A CD2 1 ATOM 2034 N N . ASP A 1 261 ? 2.473 -14.551 53.675 1.00 17.56 ? 261 ASP A N 1 ATOM 2035 C CA . ASP A 1 261 ? 2.152 -13.154 53.936 1.00 16.53 ? 261 ASP A CA 1 ATOM 2036 C C . ASP A 1 261 ? 0.703 -12.975 53.472 1.00 16.26 ? 261 ASP A C 1 ATOM 2037 O O . ASP A 1 261 ? 0.467 -12.918 52.270 1.00 14.67 ? 261 ASP A O 1 ATOM 2038 C CB . ASP A 1 261 ? 3.048 -12.284 53.078 1.00 17.94 ? 261 ASP A CB 1 ATOM 2039 C CG . ASP A 1 261 ? 2.863 -10.799 53.340 1.00 20.60 ? 261 ASP A CG 1 ATOM 2040 O OD1 . ASP A 1 261 ? 1.944 -10.449 54.097 1.00 24.73 ? 261 ASP A OD1 1 ATOM 2041 O OD2 . ASP A 1 261 ? 3.622 -9.960 52.804 1.00 19.16 ? 261 ASP A OD2 1 ATOM 2042 N N . PHE A 1 262 ? -0.234 -12.867 54.421 1.00 15.52 ? 262 PHE A N 1 ATOM 2043 C CA . PHE A 1 262 ? -1.655 -13.020 54.091 1.00 13.90 ? 262 PHE A CA 1 ATOM 2044 C C . PHE A 1 262 ? -2.383 -11.712 54.395 1.00 13.45 ? 262 PHE A C 1 ATOM 2045 O O . PHE A 1 262 ? -2.083 -11.051 55.420 1.00 13.23 ? 262 PHE A O 1 ATOM 2046 C CB . PHE A 1 262 ? -2.321 -14.121 54.940 1.00 14.52 ? 262 PHE A CB 1 ATOM 2047 C CG . PHE A 1 262 ? -2.197 -15.528 54.386 1.00 15.87 ? 262 PHE A CG 1 ATOM 2048 C CD1 . PHE A 1 262 ? -2.931 -15.943 53.262 1.00 17.94 ? 262 PHE A CD1 1 ATOM 2049 C CD2 . PHE A 1 262 ? -1.342 -16.449 55.002 1.00 16.52 ? 262 PHE A CD2 1 ATOM 2050 C CE1 . PHE A 1 262 ? -2.811 -17.255 52.774 1.00 19.16 ? 262 PHE A CE1 1 ATOM 2051 C CE2 . PHE A 1 262 ? -1.241 -17.741 54.525 1.00 14.66 ? 262 PHE A CE2 1 ATOM 2052 C CZ . PHE A 1 262 ? -1.959 -18.143 53.404 1.00 18.51 ? 262 PHE A CZ 1 ATOM 2053 N N . TYR A 1 263 ? -3.372 -11.393 53.567 1.00 13.41 ? 263 TYR A N 1 ATOM 2054 C CA . TYR A 1 263 ? -4.286 -10.263 53.835 1.00 13.33 ? 263 TYR A CA 1 ATOM 2055 C C . TYR A 1 263 ? -5.681 -10.827 53.808 1.00 13.77 ? 263 TYR A C 1 ATOM 2056 O O . TYR A 1 263 ? -5.953 -11.743 53.012 1.00 13.06 ? 263 TYR A O 1 ATOM 2057 C CB . TYR A 1 263 ? -4.181 -9.211 52.725 1.00 14.67 ? 263 TYR A CB 1 ATOM 2058 C CG . TYR A 1 263 ? -2.836 -8.481 52.711 1.00 14.14 ? 263 TYR A CG 1 ATOM 2059 C CD1 . TYR A 1 263 ? -2.701 -7.241 53.306 1.00 16.84 ? 263 TYR A CD1 1 ATOM 2060 C CD2 . TYR A 1 263 ? -1.718 -9.055 52.096 1.00 17.71 ? 263 TYR A CD2 1 ATOM 2061 C CE1 . TYR A 1 263 ? -1.510 -6.540 53.271 1.00 16.47 ? 263 TYR A CE1 1 ATOM 2062 C CE2 . TYR A 1 263 ? -0.502 -8.372 52.074 1.00 17.44 ? 263 TYR A CE2 1 ATOM 2063 C CZ . TYR A 1 263 ? -0.408 -7.139 52.670 1.00 16.78 ? 263 TYR A CZ 1 ATOM 2064 O OH . TYR A 1 263 ? 0.749 -6.429 52.674 1.00 14.61 ? 263 TYR A OH 1 ATOM 2065 N N . VAL A 1 264 ? -6.561 -10.292 54.662 1.00 12.63 ? 264 VAL A N 1 ATOM 2066 C CA . VAL A 1 264 ? -7.942 -10.755 54.710 1.00 13.36 ? 264 VAL A CA 1 ATOM 2067 C C . VAL A 1 264 ? -8.778 -9.462 54.634 1.00 12.56 ? 264 VAL A C 1 ATOM 2068 O O . VAL A 1 264 ? -8.446 -8.500 55.303 1.00 13.03 ? 264 VAL A O 1 ATOM 2069 C CB . VAL A 1 264 ? -8.241 -11.558 56.004 1.00 13.80 ? 264 VAL A CB 1 ATOM 2070 C CG1 . VAL A 1 264 ? -9.740 -11.970 56.110 1.00 13.81 ? 264 VAL A CG1 1 ATOM 2071 C CG2 . VAL A 1 264 ? -7.354 -12.846 56.138 1.00 13.50 ? 264 VAL A CG2 1 ATOM 2072 N N . PHE A 1 265 ? -9.831 -9.457 53.800 1.00 12.19 ? 265 PHE A N 1 ATOM 2073 C CA . PHE A 1 265 ? -10.552 -8.222 53.463 1.00 12.97 ? 265 PHE A CA 1 ATOM 2074 C C . PHE A 1 265 ? -11.987 -8.518 53.759 1.00 12.58 ? 265 PHE A C 1 ATOM 2075 O O . PHE A 1 265 ? -12.442 -9.588 53.389 1.00 13.34 ? 265 PHE A O 1 ATOM 2076 C CB . PHE A 1 265 ? -10.449 -7.923 51.950 1.00 12.60 ? 265 PHE A CB 1 ATOM 2077 C CG . PHE A 1 265 ? -9.021 -7.870 51.411 1.00 14.47 ? 265 PHE A CG 1 ATOM 2078 C CD1 . PHE A 1 265 ? -8.258 -6.726 51.547 1.00 12.54 ? 265 PHE A CD1 1 ATOM 2079 C CD2 . PHE A 1 265 ? -8.478 -8.962 50.741 1.00 16.65 ? 265 PHE A CD2 1 ATOM 2080 C CE1 . PHE A 1 265 ? -6.915 -6.675 51.061 1.00 15.29 ? 265 PHE A CE1 1 ATOM 2081 C CE2 . PHE A 1 265 ? -7.159 -8.922 50.238 1.00 17.48 ? 265 PHE A CE2 1 ATOM 2082 C CZ . PHE A 1 265 ? -6.389 -7.768 50.391 1.00 15.58 ? 265 PHE A CZ 1 ATOM 2083 N N . LEU A 1 266 ? -12.698 -7.577 54.371 1.00 13.58 ? 266 LEU A N 1 ATOM 2084 C CA . LEU A 1 266 ? -14.126 -7.791 54.627 1.00 13.16 ? 266 LEU A CA 1 ATOM 2085 C C . LEU A 1 266 ? -14.901 -6.731 53.903 1.00 13.23 ? 266 LEU A C 1 ATOM 2086 O O . LEU A 1 266 ? -14.458 -5.624 53.789 1.00 13.75 ? 266 LEU A O 1 ATOM 2087 C CB . LEU A 1 266 ? -14.430 -7.692 56.126 1.00 12.79 ? 266 LEU A CB 1 ATOM 2088 C CG . LEU A 1 266 ? -14.210 -8.968 56.951 1.00 13.97 ? 266 LEU A CG 1 ATOM 2089 C CD1 . LEU A 1 266 ? -12.712 -9.201 57.210 1.00 18.39 ? 266 LEU A CD1 1 ATOM 2090 C CD2 . LEU A 1 266 ? -14.906 -8.777 58.276 1.00 17.02 ? 266 LEU A CD2 1 ATOM 2091 N N . GLY A 1 267 ? -16.098 -7.060 53.443 1.00 13.69 ? 267 GLY A N 1 ATOM 2092 C CA . GLY A 1 267 ? -16.912 -6.060 52.768 1.00 13.09 ? 267 GLY A CA 1 ATOM 2093 C C . GLY A 1 267 ? -18.356 -6.406 53.032 1.00 13.26 ? 267 GLY A C 1 ATOM 2094 O O . GLY A 1 267 ? -18.678 -7.518 53.471 1.00 13.67 ? 267 GLY A O 1 ATOM 2095 N N . ASN A 1 268 ? -19.236 -5.445 52.762 1.00 13.93 ? 268 ASN A N 1 ATOM 2096 C CA . ASN A 1 268 ? -20.658 -5.696 52.927 1.00 15.34 ? 268 ASN A CA 1 ATOM 2097 C C . ASN A 1 268 ? -21.308 -6.309 51.707 1.00 15.20 ? 268 ASN A C 1 ATOM 2098 O O . ASN A 1 268 ? -22.471 -6.763 51.770 1.00 14.32 ? 268 ASN A O 1 ATOM 2099 C CB . ASN A 1 268 ? -21.386 -4.391 53.297 1.00 16.50 ? 268 ASN A CB 1 ATOM 2100 C CG . ASN A 1 268 ? -21.080 -3.955 54.712 1.00 20.38 ? 268 ASN A CG 1 ATOM 2101 O OD1 . ASN A 1 268 ? -20.718 -4.779 55.560 1.00 23.44 ? 268 ASN A OD1 1 ATOM 2102 N ND2 . ASN A 1 268 ? -21.193 -2.647 54.973 1.00 21.34 ? 268 ASN A ND2 1 ATOM 2103 N N . THR A 1 269 ? -20.573 -6.310 50.597 1.00 14.39 ? 269 THR A N 1 ATOM 2104 C CA . THR A 1 269 ? -20.991 -6.864 49.314 1.00 15.06 ? 269 THR A CA 1 ATOM 2105 C C . THR A 1 269 ? -19.752 -7.415 48.607 1.00 14.31 ? 269 THR A C 1 ATOM 2106 O O . THR A 1 269 ? -18.625 -7.026 48.982 1.00 13.66 ? 269 THR A O 1 ATOM 2107 C CB . THR A 1 269 ? -21.539 -5.763 48.376 1.00 14.36 ? 269 THR A CB 1 ATOM 2108 O OG1 . THR A 1 269 ? -20.508 -4.807 48.138 1.00 17.21 ? 269 THR A OG1 1 ATOM 2109 C CG2 . THR A 1 269 ? -22.769 -5.038 48.971 1.00 15.99 ? 269 THR A CG2 1 ATOM 2110 N N . PRO A 1 270 ? -19.939 -8.291 47.591 1.00 14.57 ? 270 PRO A N 1 ATOM 2111 C CA . PRO A 1 270 ? -18.779 -8.757 46.786 1.00 14.27 ? 270 PRO A CA 1 ATOM 2112 C C . PRO A 1 270 ? -17.980 -7.606 46.167 1.00 14.69 ? 270 PRO A C 1 ATOM 2113 O O . PRO A 1 270 ? -16.733 -7.622 46.253 1.00 13.59 ? 270 PRO A O 1 ATOM 2114 C CB . PRO A 1 270 ? -19.425 -9.651 45.718 1.00 14.63 ? 270 PRO A CB 1 ATOM 2115 C CG . PRO A 1 270 ? -20.702 -10.197 46.440 1.00 14.32 ? 270 PRO A CG 1 ATOM 2116 C CD . PRO A 1 270 ? -21.198 -8.960 47.167 1.00 13.17 ? 270 PRO A CD 1 ATOM 2117 N N . GLU A 1 271 ? -18.662 -6.576 45.640 1.00 13.79 ? 271 GLU A N 1 ATOM 2118 C CA . GLU A 1 271 ? -17.962 -5.406 45.091 1.00 14.90 ? 271 GLU A CA 1 ATOM 2119 C C . GLU A 1 271 ? -17.033 -4.705 46.097 1.00 14.60 ? 271 GLU A C 1 ATOM 2120 O O . GLU A 1 271 ? -15.893 -4.309 45.750 1.00 15.55 ? 271 GLU A O 1 ATOM 2121 C CB . GLU A 1 271 ? -18.955 -4.385 44.458 1.00 14.62 ? 271 GLU A CB 1 ATOM 2122 C CG . GLU A 1 271 ? -19.515 -4.834 43.097 1.00 17.21 ? 271 GLU A CG 1 ATOM 2123 C CD . GLU A 1 271 ? -18.446 -4.861 42.006 1.00 18.84 ? 271 GLU A CD 1 ATOM 2124 O OE1 . GLU A 1 271 ? -17.894 -3.770 41.633 1.00 18.10 ? 271 GLU A OE1 1 ATOM 2125 O OE2 . GLU A 1 271 ? -18.154 -5.989 41.549 1.00 18.96 ? 271 GLU A OE2 1 ATOM 2126 N N . GLN A 1 272 ? -17.496 -4.566 47.336 1.00 14.20 ? 272 GLN A N 1 ATOM 2127 C CA . GLN A 1 272 ? -16.682 -3.917 48.368 1.00 14.05 ? 272 GLN A CA 1 ATOM 2128 C C . GLN A 1 272 ? -15.418 -4.730 48.687 1.00 14.25 ? 272 GLN A C 1 ATOM 2129 O O . GLN A 1 272 ? -14.389 -4.139 49.000 1.00 13.72 ? 272 GLN A O 1 ATOM 2130 C CB . GLN A 1 272 ? -17.480 -3.733 49.628 1.00 13.77 ? 272 GLN A CB 1 ATOM 2131 C CG . GLN A 1 272 ? -18.495 -2.595 49.463 1.00 15.49 ? 272 GLN A CG 1 ATOM 2132 C CD . GLN A 1 272 ? -19.215 -2.297 50.720 1.00 24.23 ? 272 GLN A CD 1 ATOM 2133 O OE1 . GLN A 1 272 ? -18.871 -2.810 51.800 1.00 26.91 ? 272 GLN A OE1 1 ATOM 2134 N NE2 . GLN A 1 272 ? -20.236 -1.456 50.609 1.00 26.21 ? 272 GLN A NE2 1 ATOM 2135 N N . VAL A 1 273 ? -15.519 -6.049 48.617 1.00 13.42 ? 273 VAL A N 1 ATOM 2136 C CA . VAL A 1 273 ? -14.317 -6.938 48.830 1.00 12.90 ? 273 VAL A CA 1 ATOM 2137 C C . VAL A 1 273 ? -13.312 -6.681 47.716 1.00 14.38 ? 273 VAL A C 1 ATOM 2138 O O . VAL A 1 273 ? -12.114 -6.528 47.978 1.00 14.01 ? 273 VAL A O 1 ATOM 2139 C CB . VAL A 1 273 ? -14.666 -8.445 48.876 1.00 14.39 ? 273 VAL A CB 1 ATOM 2140 C CG1 . VAL A 1 273 ? -13.380 -9.312 48.881 1.00 13.14 ? 273 VAL A CG1 1 ATOM 2141 C CG2 . VAL A 1 273 ? -15.447 -8.749 50.134 1.00 13.77 ? 273 VAL A CG2 1 ATOM 2142 N N . VAL A 1 274 ? -13.791 -6.655 46.473 1.00 12.91 ? 274 VAL A N 1 ATOM 2143 C CA . VAL A 1 274 ? -12.912 -6.339 45.353 1.00 12.74 ? 274 VAL A CA 1 ATOM 2144 C C . VAL A 1 274 ? -12.278 -4.962 45.549 1.00 13.00 ? 274 VAL A C 1 ATOM 2145 O O . VAL A 1 274 ? -11.051 -4.792 45.356 1.00 10.89 ? 274 VAL A O 1 ATOM 2146 C CB . VAL A 1 274 ? -13.619 -6.436 43.981 1.00 13.37 ? 274 VAL A CB 1 ATOM 2147 C CG1 . VAL A 1 274 ? -12.662 -6.034 42.864 1.00 11.47 ? 274 VAL A CG1 1 ATOM 2148 C CG2 . VAL A 1 274 ? -14.144 -7.873 43.740 1.00 12.21 ? 274 VAL A CG2 1 ATOM 2149 N N . GLN A 1 275 ? -13.086 -3.963 45.943 1.00 10.49 ? 275 GLN A N 1 ATOM 2150 C CA . GLN A 1 275 ? -12.539 -2.626 46.209 1.00 11.70 ? 275 GLN A CA 1 ATOM 2151 C C . GLN A 1 275 ? -11.453 -2.686 47.299 1.00 12.76 ? 275 GLN A C 1 ATOM 2152 O O . GLN A 1 275 ? -10.402 -2.024 47.173 1.00 11.19 ? 275 GLN A O 1 ATOM 2153 C CB . GLN A 1 275 ? -13.648 -1.629 46.603 1.00 12.45 ? 275 GLN A CB 1 ATOM 2154 C CG . GLN A 1 275 ? -14.644 -1.374 45.487 1.00 11.79 ? 275 GLN A CG 1 ATOM 2155 C CD . GLN A 1 275 ? -15.943 -0.699 45.998 1.00 15.67 ? 275 GLN A CD 1 ATOM 2156 O OE1 . GLN A 1 275 ? -16.236 -0.730 47.184 1.00 16.20 ? 275 GLN A OE1 1 ATOM 2157 N NE2 . GLN A 1 275 ? -16.718 -0.130 45.082 1.00 16.73 ? 275 GLN A NE2 1 ATOM 2158 N N . GLU A 1 276 ? -11.676 -3.475 48.348 1.00 10.93 ? 276 GLU A N 1 ATOM 2159 C CA . GLU A 1 276 ? -10.668 -3.567 49.427 1.00 12.05 ? 276 GLU A CA 1 ATOM 2160 C C . GLU A 1 276 ? -9.383 -4.214 48.935 1.00 12.01 ? 276 GLU A C 1 ATOM 2161 O O . GLU A 1 276 ? -8.291 -3.733 49.277 1.00 12.19 ? 276 GLU A O 1 ATOM 2162 C CB . GLU A 1 276 ? -11.184 -4.381 50.625 1.00 13.29 ? 276 GLU A CB 1 ATOM 2163 C CG . GLU A 1 276 ? -12.337 -3.703 51.388 1.00 14.56 ? 276 GLU A CG 1 ATOM 2164 C CD . GLU A 1 276 ? -11.911 -2.414 52.085 1.00 21.86 ? 276 GLU A CD 1 ATOM 2165 O OE1 . GLU A 1 276 ? -10.681 -2.182 52.267 1.00 25.03 ? 276 GLU A OE1 1 ATOM 2166 O OE2 . GLU A 1 276 ? -12.805 -1.622 52.482 1.00 24.23 ? 276 GLU A OE2 1 ATOM 2167 N N . TYR A 1 277 ? -9.530 -5.283 48.155 1.00 11.70 ? 277 TYR A N 1 ATOM 2168 C CA . TYR A 1 277 ? -8.350 -5.966 47.539 1.00 13.75 ? 277 TYR A CA 1 ATOM 2169 C C . TYR A 1 277 ? -7.542 -5.002 46.640 1.00 13.48 ? 277 TYR A C 1 ATOM 2170 O O . TYR A 1 277 ? -6.321 -4.872 46.773 1.00 12.63 ? 277 TYR A O 1 ATOM 2171 C CB . TYR A 1 277 ? -8.815 -7.219 46.759 1.00 15.27 ? 277 TYR A CB 1 ATOM 2172 C CG . TYR A 1 277 ? -7.706 -7.855 45.967 1.00 13.08 ? 277 TYR A CG 1 ATOM 2173 C CD1 . TYR A 1 277 ? -6.507 -8.226 46.595 1.00 13.25 ? 277 TYR A CD1 1 ATOM 2174 C CD2 . TYR A 1 277 ? -7.848 -8.066 44.607 1.00 13.14 ? 277 TYR A CD2 1 ATOM 2175 C CE1 . TYR A 1 277 ? -5.463 -8.813 45.866 1.00 15.45 ? 277 TYR A CE1 1 ATOM 2176 C CE2 . TYR A 1 277 ? -6.827 -8.655 43.860 1.00 15.71 ? 277 TYR A CE2 1 ATOM 2177 C CZ . TYR A 1 277 ? -5.637 -9.003 44.503 1.00 15.45 ? 277 TYR A CZ 1 ATOM 2178 O OH . TYR A 1 277 ? -4.638 -9.567 43.757 1.00 15.72 ? 277 TYR A OH 1 ATOM 2179 N N . LEU A 1 278 ? -8.231 -4.255 45.788 1.00 12.60 ? 278 LEU A N 1 ATOM 2180 C CA . LEU A 1 278 ? -7.581 -3.338 44.855 1.00 13.66 ? 278 LEU A CA 1 ATOM 2181 C C . LEU A 1 278 ? -6.972 -2.110 45.516 1.00 14.59 ? 278 LEU A C 1 ATOM 2182 O O . LEU A 1 278 ? -5.956 -1.547 45.018 1.00 13.43 ? 278 LEU A O 1 ATOM 2183 C CB . LEU A 1 278 ? -8.525 -2.953 43.692 1.00 15.04 ? 278 LEU A CB 1 ATOM 2184 C CG . LEU A 1 278 ? -8.950 -4.208 42.881 1.00 12.63 ? 278 LEU A CG 1 ATOM 2185 C CD1 . LEU A 1 278 ? -9.790 -3.780 41.723 1.00 12.56 ? 278 LEU A CD1 1 ATOM 2186 C CD2 . LEU A 1 278 ? -7.709 -5.064 42.364 1.00 13.22 ? 278 LEU A CD2 1 ATOM 2187 N N . GLU A 1 279 ? -7.591 -1.662 46.607 1.00 13.53 ? 279 GLU A N 1 ATOM 2188 C CA . GLU A 1 279 ? -7.003 -0.589 47.432 1.00 15.12 ? 279 GLU A CA 1 ATOM 2189 C C . GLU A 1 279 ? -5.632 -1.023 47.933 1.00 15.47 ? 279 GLU A C 1 ATOM 2190 O O . GLU A 1 279 ? -4.704 -0.216 48.007 1.00 17.13 ? 279 GLU A O 1 ATOM 2191 C CB . GLU A 1 279 ? -7.903 -0.254 48.619 1.00 15.83 ? 279 GLU A CB 1 ATOM 2192 C CG . GLU A 1 279 ? -7.214 0.576 49.742 1.00 19.19 ? 279 GLU A CG 1 ATOM 2193 C CD . GLU A 1 279 ? -6.778 1.973 49.304 1.00 25.65 ? 279 GLU A CD 1 ATOM 2194 O OE1 . GLU A 1 279 ? -7.326 2.521 48.302 1.00 24.86 ? 279 GLU A OE1 1 ATOM 2195 O OE2 . GLU A 1 279 ? -5.867 2.539 49.963 1.00 24.35 ? 279 GLU A OE2 1 ATOM 2196 N N . LEU A 1 280 ? -5.514 -2.290 48.279 1.00 15.23 ? 280 LEU A N 1 ATOM 2197 C CA . LEU A 1 280 ? -4.203 -2.849 48.686 1.00 14.85 ? 280 LEU A CA 1 ATOM 2198 C C . LEU A 1 280 ? -3.225 -2.973 47.503 1.00 15.51 ? 280 LEU A C 1 ATOM 2199 O O . LEU A 1 280 ? -2.147 -2.340 47.475 1.00 14.34 ? 280 LEU A O 1 ATOM 2200 C CB . LEU A 1 280 ? -4.376 -4.187 49.413 1.00 14.15 ? 280 LEU A CB 1 ATOM 2201 C CG . LEU A 1 280 ? -2.964 -4.769 49.685 1.00 16.70 ? 280 LEU A CG 1 ATOM 2202 C CD1 . LEU A 1 280 ? -2.262 -3.940 50.774 1.00 12.79 ? 280 LEU A CD1 1 ATOM 2203 C CD2 . LEU A 1 280 ? -3.033 -6.209 49.994 1.00 14.32 ? 280 LEU A CD2 1 ATOM 2204 N N . ILE A 1 281 ? -3.630 -3.739 46.506 1.00 14.54 ? 281 ILE A N 1 ATOM 2205 C CA . ILE A 1 281 ? -2.695 -4.233 45.484 1.00 16.29 ? 281 ILE A CA 1 ATOM 2206 C C . ILE A 1 281 ? -2.485 -3.258 44.332 1.00 16.01 ? 281 ILE A C 1 ATOM 2207 O O . ILE A 1 281 ? -1.508 -3.371 43.613 1.00 15.61 ? 281 ILE A O 1 ATOM 2208 C CB . ILE A 1 281 ? -3.179 -5.624 44.984 1.00 17.26 ? 281 ILE A CB 1 ATOM 2209 C CG1 . ILE A 1 281 ? -2.011 -6.481 44.514 1.00 19.86 ? 281 ILE A CG1 1 ATOM 2210 C CG2 . ILE A 1 281 ? -4.297 -5.485 43.919 1.00 15.18 ? 281 ILE A CG2 1 ATOM 2211 C CD1 . ILE A 1 281 ? -1.214 -7.020 45.678 1.00 21.61 ? 281 ILE A CD1 1 ATOM 2212 N N . GLY A 1 282 ? -3.363 -2.253 44.194 1.00 13.07 ? 282 GLY A N 1 ATOM 2213 C CA . GLY A 1 282 ? -3.244 -1.313 43.092 1.00 14.82 ? 282 GLY A CA 1 ATOM 2214 C C . GLY A 1 282 ? -4.474 -1.416 42.203 1.00 14.39 ? 282 GLY A C 1 ATOM 2215 O O . GLY A 1 282 ? -4.743 -2.487 41.651 1.00 14.09 ? 282 GLY A O 1 ATOM 2216 N N . ARG A 1 283 ? -5.199 -0.301 42.058 1.00 13.80 ? 283 ARG A N 1 ATOM 2217 C CA . ARG A 1 283 ? -6.359 -0.276 41.157 1.00 13.75 ? 283 ARG A CA 1 ATOM 2218 C C . ARG A 1 283 ? -5.914 -0.250 39.718 1.00 14.92 ? 283 ARG A C 1 ATOM 2219 O O . ARG A 1 283 ? -4.783 0.230 39.405 1.00 15.42 ? 283 ARG A O 1 ATOM 2220 C CB . ARG A 1 283 ? -7.288 0.929 41.470 1.00 13.02 ? 283 ARG A CB 1 ATOM 2221 C CG . ARG A 1 283 ? -8.099 0.690 42.676 1.00 12.09 ? 283 ARG A CG 1 ATOM 2222 C CD . ARG A 1 283 ? -9.038 1.903 42.971 1.00 15.84 ? 283 ARG A CD 1 ATOM 2223 N NE . ARG A 1 283 ? -8.251 3.061 43.422 1.00 16.26 ? 283 ARG A NE 1 ATOM 2224 C CZ . ARG A 1 283 ? -7.898 3.279 44.684 1.00 18.24 ? 283 ARG A CZ 1 ATOM 2225 N NH1 . ARG A 1 283 ? -8.258 2.455 45.672 1.00 19.66 ? 283 ARG A NH1 1 ATOM 2226 N NH2 . ARG A 1 283 ? -7.195 4.347 44.966 1.00 23.19 ? 283 ARG A NH2 1 ATOM 2227 N N . PRO A 1 284 ? -6.769 -0.749 38.811 1.00 14.24 ? 284 PRO A N 1 ATOM 2228 C CA . PRO A 1 284 ? -6.337 -0.762 37.402 1.00 15.09 ? 284 PRO A CA 1 ATOM 2229 C C . PRO A 1 284 ? -6.158 0.613 36.785 1.00 14.89 ? 284 PRO A C 1 ATOM 2230 O O . PRO A 1 284 ? -6.802 1.589 37.203 1.00 16.52 ? 284 PRO A O 1 ATOM 2231 C CB . PRO A 1 284 ? -7.487 -1.459 36.672 1.00 15.29 ? 284 PRO A CB 1 ATOM 2232 C CG . PRO A 1 284 ? -8.686 -1.274 37.605 1.00 14.70 ? 284 PRO A CG 1 ATOM 2233 C CD . PRO A 1 284 ? -8.141 -1.301 38.991 1.00 14.35 ? 284 PRO A CD 1 ATOM 2234 N N . ALA A 1 285 ? -5.273 0.688 35.804 1.00 15.26 ? 285 ALA A N 1 ATOM 2235 C CA . ALA A 1 285 ? -5.088 1.884 35.010 1.00 15.60 ? 285 ALA A CA 1 ATOM 2236 C C . ALA A 1 285 ? -6.387 2.241 34.292 1.00 15.86 ? 285 ALA A C 1 ATOM 2237 O O . ALA A 1 285 ? -7.139 1.353 33.891 1.00 16.04 ? 285 ALA A O 1 ATOM 2238 C CB . ALA A 1 285 ? -3.969 1.660 33.989 1.00 15.69 ? 285 ALA A CB 1 ATOM 2239 N N . LEU A 1 286 ? -6.639 3.530 34.125 1.00 15.81 ? 286 LEU A N 1 ATOM 2240 C CA . LEU A 1 286 ? -7.710 3.963 33.232 1.00 16.71 ? 286 LEU A CA 1 ATOM 2241 C C . LEU A 1 286 ? -7.171 3.798 31.829 1.00 15.72 ? 286 LEU A C 1 ATOM 2242 O O . LEU A 1 286 ? -6.091 4.362 31.495 1.00 17.06 ? 286 LEU A O 1 ATOM 2243 C CB . LEU A 1 286 ? -8.103 5.426 33.508 1.00 16.30 ? 286 LEU A CB 1 ATOM 2244 C CG . LEU A 1 286 ? -9.276 6.059 32.742 1.00 17.30 ? 286 LEU A CG 1 ATOM 2245 C CD1 . LEU A 1 286 ? -10.615 5.397 33.070 1.00 17.87 ? 286 LEU A CD1 1 ATOM 2246 C CD2 . LEU A 1 286 ? -9.330 7.547 33.101 1.00 17.47 ? 286 LEU A CD2 1 ATOM 2247 N N . PRO A 1 287 ? -7.887 3.028 30.991 1.00 16.31 ? 287 PRO A N 1 ATOM 2248 C CA . PRO A 1 287 ? -7.373 2.830 29.640 1.00 16.25 ? 287 PRO A CA 1 ATOM 2249 C C . PRO A 1 287 ? -7.525 4.090 28.790 1.00 15.85 ? 287 PRO A C 1 ATOM 2250 O O . PRO A 1 287 ? -8.343 4.986 29.122 1.00 15.65 ? 287 PRO A O 1 ATOM 2251 C CB . PRO A 1 287 ? -8.277 1.741 29.068 1.00 16.35 ? 287 PRO A CB 1 ATOM 2252 C CG . PRO A 1 287 ? -9.564 1.920 29.804 1.00 18.37 ? 287 PRO A CG 1 ATOM 2253 C CD . PRO A 1 287 ? -9.182 2.344 31.198 1.00 16.19 ? 287 PRO A CD 1 ATOM 2254 N N . SER A 1 288 ? -6.764 4.147 27.700 1.00 15.09 ? 288 SER A N 1 ATOM 2255 C CA . SER A 1 288 ? -7.040 5.124 26.640 1.00 13.82 ? 288 SER A CA 1 ATOM 2256 C C . SER A 1 288 ? -8.406 4.773 26.125 1.00 14.34 ? 288 SER A C 1 ATOM 2257 O O . SER A 1 288 ? -8.761 3.588 26.017 1.00 11.87 ? 288 SER A O 1 ATOM 2258 C CB . SER A 1 288 ? -6.040 5.005 25.504 1.00 14.60 ? 288 SER A CB 1 ATOM 2259 O OG . SER A 1 288 ? -4.741 5.351 26.003 1.00 12.59 ? 288 SER A OG 1 ATOM 2260 N N . TYR A 1 289 ? -9.189 5.793 25.821 1.00 13.81 ? 289 TYR A N 1 ATOM 2261 C CA . TYR A 1 289 ? -10.564 5.509 25.365 1.00 13.97 ? 289 TYR A CA 1 ATOM 2262 C C . TYR A 1 289 ? -10.547 4.682 24.066 1.00 14.65 ? 289 TYR A C 1 ATOM 2263 O O . TYR A 1 289 ? -11.408 3.821 23.854 1.00 14.53 ? 289 TYR A O 1 ATOM 2264 C CB . TYR A 1 289 ? -11.253 6.851 25.183 1.00 14.95 ? 289 TYR A CB 1 ATOM 2265 C CG . TYR A 1 289 ? -12.752 6.818 24.993 1.00 15.33 ? 289 TYR A CG 1 ATOM 2266 C CD1 . TYR A 1 289 ? -13.605 7.101 26.049 1.00 17.42 ? 289 TYR A CD1 1 ATOM 2267 C CD2 . TYR A 1 289 ? -13.297 6.616 23.736 1.00 15.47 ? 289 TYR A CD2 1 ATOM 2268 C CE1 . TYR A 1 289 ? -15.023 7.141 25.845 1.00 16.19 ? 289 TYR A CE1 1 ATOM 2269 C CE2 . TYR A 1 289 ? -14.710 6.644 23.527 1.00 18.13 ? 289 TYR A CE2 1 ATOM 2270 C CZ . TYR A 1 289 ? -15.535 6.927 24.600 1.00 15.53 ? 289 TYR A CZ 1 ATOM 2271 O OH . TYR A 1 289 ? -16.911 6.988 24.419 1.00 16.15 ? 289 TYR A OH 1 ATOM 2272 N N . TRP A 1 290 ? -9.513 4.864 23.226 1.00 14.14 ? 290 TRP A N 1 ATOM 2273 C CA . TRP A 1 290 ? -9.453 4.089 21.984 1.00 14.63 ? 290 TRP A CA 1 ATOM 2274 C C . TRP A 1 290 ? -9.256 2.575 22.173 1.00 14.25 ? 290 TRP A C 1 ATOM 2275 O O . TRP A 1 290 ? -9.649 1.777 21.309 1.00 13.42 ? 290 TRP A O 1 ATOM 2276 C CB . TRP A 1 290 ? -8.392 4.636 21.040 1.00 16.14 ? 290 TRP A CB 1 ATOM 2277 C CG . TRP A 1 290 ? -6.950 4.701 21.556 1.00 14.56 ? 290 TRP A CG 1 ATOM 2278 C CD1 . TRP A 1 290 ? -6.304 5.791 22.011 1.00 15.63 ? 290 TRP A CD1 1 ATOM 2279 C CD2 . TRP A 1 290 ? -5.976 3.631 21.534 1.00 15.96 ? 290 TRP A CD2 1 ATOM 2280 N NE1 . TRP A 1 290 ? -4.983 5.480 22.290 1.00 14.54 ? 290 TRP A NE1 1 ATOM 2281 C CE2 . TRP A 1 290 ? -4.772 4.153 22.032 1.00 15.58 ? 290 TRP A CE2 1 ATOM 2282 C CE3 . TRP A 1 290 ? -6.038 2.274 21.202 1.00 15.23 ? 290 TRP A CE3 1 ATOM 2283 C CZ2 . TRP A 1 290 ? -3.591 3.364 22.145 1.00 16.30 ? 290 TRP A CZ2 1 ATOM 2284 C CZ3 . TRP A 1 290 ? -4.887 1.498 21.303 1.00 17.59 ? 290 TRP A CZ3 1 ATOM 2285 C CH2 . TRP A 1 290 ? -3.684 2.051 21.773 1.00 15.80 ? 290 TRP A CH2 1 ATOM 2286 N N . ALA A 1 291 ? -8.645 2.206 23.300 1.00 13.62 ? 291 ALA A N 1 ATOM 2287 C CA . ALA A 1 291 ? -8.405 0.793 23.638 1.00 14.87 ? 291 ALA A CA 1 ATOM 2288 C C . ALA A 1 291 ? -9.699 0.054 23.923 1.00 14.90 ? 291 ALA A C 1 ATOM 2289 O O . ALA A 1 291 ? -9.731 -1.156 23.918 1.00 13.58 ? 291 ALA A O 1 ATOM 2290 C CB . ALA A 1 291 ? -7.493 0.694 24.824 1.00 14.54 ? 291 ALA A CB 1 ATOM 2291 N N . LEU A 1 292 ? -10.779 0.804 24.183 1.00 14.82 ? 292 LEU A N 1 ATOM 2292 C CA . LEU A 1 292 ? -12.102 0.203 24.408 1.00 15.25 ? 292 LEU A CA 1 ATOM 2293 C C . LEU A 1 292 ? -12.756 -0.195 23.086 1.00 15.25 ? 292 LEU A C 1 ATOM 2294 O O . LEU A 1 292 ? -13.780 -0.882 23.046 1.00 15.86 ? 292 LEU A O 1 ATOM 2295 C CB . LEU A 1 292 ? -13.026 1.200 25.152 1.00 15.72 ? 292 LEU A CB 1 ATOM 2296 C CG . LEU A 1 292 ? -12.650 1.688 26.568 1.00 18.99 ? 292 LEU A CG 1 ATOM 2297 C CD1 . LEU A 1 292 ? -13.791 2.583 27.077 1.00 21.75 ? 292 LEU A CD1 1 ATOM 2298 C CD2 . LEU A 1 292 ? -12.457 0.527 27.474 1.00 23.21 ? 292 LEU A CD2 1 ATOM 2299 N N . GLY A 1 293 ? -12.186 0.232 21.980 1.00 15.31 ? 293 GLY A N 1 ATOM 2300 C CA . GLY A 1 293 ? -12.760 -0.129 20.690 1.00 14.96 ? 293 GLY A CA 1 ATOM 2301 C C . GLY A 1 293 ? -12.441 -1.559 20.319 1.00 14.64 ? 293 GLY A C 1 ATOM 2302 O O . GLY A 1 293 ? -11.891 -2.330 21.127 1.00 16.22 ? 293 GLY A O 1 ATOM 2303 N N . PHE A 1 294 ? -12.738 -1.914 19.084 1.00 14.08 ? 294 PHE A N 1 ATOM 2304 C CA . PHE A 1 294 ? -12.503 -3.261 18.611 1.00 14.02 ? 294 PHE A CA 1 ATOM 2305 C C . PHE A 1 294 ? -11.060 -3.339 18.083 1.00 14.16 ? 294 PHE A C 1 ATOM 2306 O O . PHE A 1 294 ? -10.608 -2.408 17.400 1.00 14.69 ? 294 PHE A O 1 ATOM 2307 C CB . PHE A 1 294 ? -13.463 -3.588 17.491 1.00 13.62 ? 294 PHE A CB 1 ATOM 2308 C CG . PHE A 1 294 ? -13.267 -4.967 16.898 1.00 15.57 ? 294 PHE A CG 1 ATOM 2309 C CD1 . PHE A 1 294 ? -13.476 -6.123 17.682 1.00 14.37 ? 294 PHE A CD1 1 ATOM 2310 C CD2 . PHE A 1 294 ? -12.925 -5.108 15.560 1.00 16.48 ? 294 PHE A CD2 1 ATOM 2311 C CE1 . PHE A 1 294 ? -13.325 -7.416 17.129 1.00 15.77 ? 294 PHE A CE1 1 ATOM 2312 C CE2 . PHE A 1 294 ? -12.751 -6.395 14.990 1.00 17.11 ? 294 PHE A CE2 1 ATOM 2313 C CZ . PHE A 1 294 ? -12.928 -7.549 15.782 1.00 16.67 ? 294 PHE A CZ 1 ATOM 2314 N N . HIS A 1 295 ? -10.374 -4.441 18.383 1.00 14.36 ? 295 HIS A N 1 ATOM 2315 C CA . HIS A 1 295 ? -8.982 -4.677 17.974 1.00 15.05 ? 295 HIS A CA 1 ATOM 2316 C C . HIS A 1 295 ? -8.951 -5.866 16.994 1.00 15.20 ? 295 HIS A C 1 ATOM 2317 O O . HIS A 1 295 ? -9.694 -6.861 17.170 1.00 14.69 ? 295 HIS A O 1 ATOM 2318 C CB . HIS A 1 295 ? -8.114 -5.092 19.170 1.00 15.17 ? 295 HIS A CB 1 ATOM 2319 C CG . HIS A 1 295 ? -7.938 -4.058 20.250 1.00 16.30 ? 295 HIS A CG 1 ATOM 2320 N ND1 . HIS A 1 295 ? -8.978 -3.560 21.023 1.00 18.74 ? 295 HIS A ND1 1 ATOM 2321 C CD2 . HIS A 1 295 ? -6.810 -3.495 20.737 1.00 11.15 ? 295 HIS A CD2 1 ATOM 2322 C CE1 . HIS A 1 295 ? -8.488 -2.708 21.916 1.00 11.28 ? 295 HIS A CE1 1 ATOM 2323 N NE2 . HIS A 1 295 ? -7.177 -2.649 21.750 1.00 19.33 ? 295 HIS A NE2 1 ATOM 2324 N N . LEU A 1 296 ? -8.090 -5.803 15.975 1.00 14.96 ? 296 LEU A N 1 ATOM 2325 C CA . LEU A 1 296 ? -8.007 -6.901 14.999 1.00 15.32 ? 296 LEU A CA 1 ATOM 2326 C C . LEU A 1 296 ? -6.533 -7.316 14.859 1.00 15.41 ? 296 LEU A C 1 ATOM 2327 O O . LEU A 1 296 ? -5.644 -6.470 14.908 1.00 15.50 ? 296 LEU A O 1 ATOM 2328 C CB . LEU A 1 296 ? -8.584 -6.451 13.655 1.00 16.04 ? 296 LEU A CB 1 ATOM 2329 C CG . LEU A 1 296 ? -8.724 -7.504 12.555 1.00 17.69 ? 296 LEU A CG 1 ATOM 2330 C CD1 . LEU A 1 296 ? -9.656 -8.681 12.980 1.00 18.79 ? 296 LEU A CD1 1 ATOM 2331 C CD2 . LEU A 1 296 ? -9.158 -6.872 11.246 1.00 15.73 ? 296 LEU A CD2 1 ATOM 2332 N N . SER A 1 297 ? -6.286 -8.604 14.693 1.00 16.46 ? 297 SER A N 1 ATOM 2333 C CA . SER A 1 297 ? -4.918 -9.127 14.805 1.00 17.44 ? 297 SER A CA 1 ATOM 2334 C C . SER A 1 297 ? -4.839 -10.486 14.131 1.00 17.43 ? 297 SER A C 1 ATOM 2335 O O . SER A 1 297 ? -5.842 -11.198 14.000 1.00 17.96 ? 297 SER A O 1 ATOM 2336 C CB . SER A 1 297 ? -4.575 -9.274 16.302 1.00 17.36 ? 297 SER A CB 1 ATOM 2337 O OG . SER A 1 297 ? -3.253 -9.772 16.494 1.00 20.15 ? 297 SER A OG 1 ATOM 2338 N N . ARG A 1 298 ? -3.648 -10.878 13.675 1.00 17.35 ? 298 ARG A N 1 ATOM 2339 C CA . ARG A 1 298 ? -3.415 -12.307 13.493 1.00 16.84 ? 298 ARG A CA 1 ATOM 2340 C C . ARG A 1 298 ? -1.956 -12.561 13.541 1.00 17.41 ? 298 ARG A C 1 ATOM 2341 O O . ARG A 1 298 ? -1.143 -11.658 13.328 1.00 16.54 ? 298 ARG A O 1 ATOM 2342 C CB . ARG A 1 298 ? -4.002 -12.915 12.210 1.00 16.85 ? 298 ARG A CB 1 ATOM 2343 C CG . ARG A 1 298 ? -3.208 -12.702 10.931 1.00 18.05 ? 298 ARG A CG 1 ATOM 2344 C CD . ARG A 1 298 ? -3.617 -13.669 9.783 1.00 19.18 ? 298 ARG A CD 1 ATOM 2345 N NE . ARG A 1 298 ? -3.378 -15.088 10.114 1.00 21.42 ? 298 ARG A NE 1 ATOM 2346 C CZ . ARG A 1 298 ? -4.065 -16.112 9.600 1.00 22.14 ? 298 ARG A CZ 1 ATOM 2347 N NH1 . ARG A 1 298 ? -5.061 -15.900 8.737 1.00 21.31 ? 298 ARG A NH1 1 ATOM 2348 N NH2 . ARG A 1 298 ? -3.772 -17.367 9.966 1.00 20.62 ? 298 ARG A NH2 1 ATOM 2349 N N . TYR A 1 299 ? -1.640 -13.811 13.824 1.00 17.70 ? 299 TYR A N 1 ATOM 2350 C CA . TYR A 1 299 ? -0.275 -14.269 13.772 1.00 18.62 ? 299 TYR A CA 1 ATOM 2351 C C . TYR A 1 299 ? -0.056 -14.632 12.293 1.00 18.72 ? 299 TYR A C 1 ATOM 2352 O O . TYR A 1 299 ? -0.802 -15.430 11.716 1.00 19.37 ? 299 TYR A O 1 ATOM 2353 C CB . TYR A 1 299 ? -0.132 -15.446 14.738 1.00 18.34 ? 299 TYR A CB 1 ATOM 2354 C CG . TYR A 1 299 ? 1.224 -16.130 14.790 1.00 19.70 ? 299 TYR A CG 1 ATOM 2355 C CD1 . TYR A 1 299 ? 1.351 -17.379 15.411 1.00 20.31 ? 299 TYR A CD1 1 ATOM 2356 C CD2 . TYR A 1 299 ? 2.354 -15.550 14.236 1.00 19.59 ? 299 TYR A CD2 1 ATOM 2357 C CE1 . TYR A 1 299 ? 2.586 -18.041 15.479 1.00 21.46 ? 299 TYR A CE1 1 ATOM 2358 C CE2 . TYR A 1 299 ? 3.615 -16.211 14.298 1.00 21.96 ? 299 TYR A CE2 1 ATOM 2359 C CZ . TYR A 1 299 ? 3.701 -17.459 14.915 1.00 21.24 ? 299 TYR A CZ 1 ATOM 2360 O OH . TYR A 1 299 ? 4.907 -18.145 14.999 1.00 21.66 ? 299 TYR A OH 1 ATOM 2361 N N . GLU A 1 300 ? 0.910 -13.972 11.671 1.00 19.74 ? 300 GLU A N 1 ATOM 2362 C CA . GLU A 1 300 ? 1.330 -14.265 10.304 1.00 21.30 ? 300 GLU A CA 1 ATOM 2363 C C . GLU A 1 300 ? 0.291 -13.846 9.255 1.00 21.42 ? 300 GLU A C 1 ATOM 2364 O O . GLU A 1 300 ? -0.299 -14.686 8.571 1.00 21.98 ? 300 GLU A O 1 ATOM 2365 C CB . GLU A 1 300 ? 1.805 -15.723 10.118 1.00 21.92 ? 300 GLU A CB 1 ATOM 2366 C CG . GLU A 1 300 ? 3.169 -16.036 10.746 1.00 27.30 ? 300 GLU A CG 1 ATOM 2367 C CD . GLU A 1 300 ? 4.361 -15.561 9.952 1.00 31.07 ? 300 GLU A CD 1 ATOM 2368 O OE1 . GLU A 1 300 ? 4.213 -15.256 8.743 1.00 31.48 ? 300 GLU A OE1 1 ATOM 2369 O OE2 . GLU A 1 300 ? 5.463 -15.493 10.555 1.00 36.47 ? 300 GLU A OE2 1 ATOM 2370 N N . TYR A 1 301 ? 0.089 -12.536 9.128 1.00 20.90 ? 301 TYR A N 1 ATOM 2371 C CA . TYR A 1 301 ? -0.352 -11.982 7.843 1.00 20.55 ? 301 TYR A CA 1 ATOM 2372 C C . TYR A 1 301 ? 0.710 -12.303 6.792 1.00 20.94 ? 301 TYR A C 1 ATOM 2373 O O . TYR A 1 301 ? 0.373 -12.536 5.643 1.00 20.33 ? 301 TYR A O 1 ATOM 2374 C CB . TYR A 1 301 ? -0.566 -10.480 7.891 1.00 20.04 ? 301 TYR A CB 1 ATOM 2375 C CG . TYR A 1 301 ? -1.724 -10.076 8.763 1.00 19.39 ? 301 TYR A CG 1 ATOM 2376 C CD1 . TYR A 1 301 ? -3.044 -10.237 8.318 1.00 17.70 ? 301 TYR A CD1 1 ATOM 2377 C CD2 . TYR A 1 301 ? -1.491 -9.547 10.035 1.00 20.49 ? 301 TYR A CD2 1 ATOM 2378 C CE1 . TYR A 1 301 ? -4.133 -9.863 9.143 1.00 19.27 ? 301 TYR A CE1 1 ATOM 2379 C CE2 . TYR A 1 301 ? -2.549 -9.151 10.852 1.00 18.66 ? 301 TYR A CE2 1 ATOM 2380 C CZ . TYR A 1 301 ? -3.863 -9.317 10.398 1.00 18.77 ? 301 TYR A CZ 1 ATOM 2381 O OH . TYR A 1 301 ? -4.906 -8.956 11.227 1.00 18.83 ? 301 TYR A OH 1 ATOM 2382 N N . GLY A 1 302 ? 1.977 -12.324 7.201 1.00 21.30 ? 302 GLY A N 1 ATOM 2383 C CA . GLY A 1 302 ? 3.072 -12.745 6.305 1.00 21.50 ? 302 GLY A CA 1 ATOM 2384 C C . GLY A 1 302 ? 3.721 -11.557 5.634 1.00 21.05 ? 302 GLY A C 1 ATOM 2385 O O . GLY A 1 302 ? 4.957 -11.437 5.611 1.00 20.80 ? 302 GLY A O 1 ATOM 2386 N N . THR A 1 303 ? 2.885 -10.680 5.083 1.00 20.41 ? 303 THR A N 1 ATOM 2387 C CA . THR A 1 303 ? 3.305 -9.459 4.429 1.00 21.12 ? 303 THR A CA 1 ATOM 2388 C C . THR A 1 303 ? 2.420 -8.292 4.808 1.00 21.19 ? 303 THR A C 1 ATOM 2389 O O . THR A 1 303 ? 1.266 -8.477 5.190 1.00 20.41 ? 303 THR A O 1 ATOM 2390 C CB . THR A 1 303 ? 3.268 -9.539 2.855 1.00 20.51 ? 303 THR A CB 1 ATOM 2391 O OG1 . THR A 1 303 ? 1.916 -9.666 2.374 1.00 22.10 ? 303 THR A OG1 1 ATOM 2392 C CG2 . THR A 1 303 ? 4.078 -10.716 2.353 1.00 22.62 ? 303 THR A CG2 1 ATOM 2393 N N . LEU A 1 304 ? 2.971 -7.094 4.646 1.00 21.37 ? 304 LEU A N 1 ATOM 2394 C CA . LEU A 1 304 ? 2.215 -5.879 4.874 1.00 21.15 ? 304 LEU A CA 1 ATOM 2395 C C . LEU A 1 304 ? 1.062 -5.756 3.879 1.00 22.46 ? 304 LEU A C 1 ATOM 2396 O O . LEU A 1 304 ? -0.002 -5.234 4.231 1.00 22.85 ? 304 LEU A O 1 ATOM 2397 C CB . LEU A 1 304 ? 3.142 -4.680 4.786 1.00 20.95 ? 304 LEU A CB 1 ATOM 2398 C CG . LEU A 1 304 ? 2.520 -3.309 5.010 1.00 20.27 ? 304 LEU A CG 1 ATOM 2399 C CD1 . LEU A 1 304 ? 1.886 -3.276 6.399 1.00 18.45 ? 304 LEU A CD1 1 ATOM 2400 C CD2 . LEU A 1 304 ? 3.580 -2.218 4.863 1.00 19.18 ? 304 LEU A CD2 1 ATOM 2401 N N . ASP A 1 305 ? 1.277 -6.201 2.639 1.00 23.34 ? 305 ASP A N 1 ATOM 2402 C CA . ASP A 1 305 ? 0.210 -6.246 1.625 1.00 24.50 ? 305 ASP A CA 1 ATOM 2403 C C . ASP A 1 305 ? -0.994 -7.070 2.093 1.00 23.74 ? 305 ASP A C 1 ATOM 2404 O O . ASP A 1 305 ? -2.153 -6.667 1.909 1.00 22.18 ? 305 ASP A O 1 ATOM 2405 C CB . ASP A 1 305 ? 0.715 -6.840 0.307 1.00 26.17 ? 305 ASP A CB 1 ATOM 2406 C CG . ASP A 1 305 ? 1.588 -5.880 -0.511 1.00 29.79 ? 305 ASP A CG 1 ATOM 2407 O OD1 . ASP A 1 305 ? 1.770 -4.690 -0.159 1.00 34.21 ? 305 ASP A OD1 1 ATOM 2408 O OD2 . ASP A 1 305 ? 2.090 -6.349 -1.559 1.00 35.24 ? 305 ASP A OD2 1 ATOM 2409 N N . ASN A 1 306 ? -0.708 -8.234 2.671 1.00 22.68 ? 306 ASN A N 1 ATOM 2410 C CA . ASN A 1 306 ? -1.737 -9.090 3.257 1.00 23.49 ? 306 ASN A CA 1 ATOM 2411 C C . ASN A 1 306 ? -2.414 -8.441 4.455 1.00 22.69 ? 306 ASN A C 1 ATOM 2412 O O . ASN A 1 306 ? -3.631 -8.512 4.570 1.00 23.95 ? 306 ASN A O 1 ATOM 2413 C CB . ASN A 1 306 ? -1.155 -10.453 3.656 1.00 23.71 ? 306 ASN A CB 1 ATOM 2414 C CG . ASN A 1 306 ? -0.840 -11.326 2.451 1.00 26.03 ? 306 ASN A CG 1 ATOM 2415 O OD1 . ASN A 1 306 ? -1.363 -11.113 1.355 1.00 27.98 ? 306 ASN A OD1 1 ATOM 2416 N ND2 . ASN A 1 306 ? 0.014 -12.314 2.652 1.00 27.28 ? 306 ASN A ND2 1 ATOM 2417 N N . MET A 1 307 ? -1.635 -7.811 5.338 1.00 22.46 ? 307 MET A N 1 ATOM 2418 C CA . MET A 1 307 ? -2.216 -7.068 6.477 1.00 22.51 ? 307 MET A CA 1 ATOM 2419 C C . MET A 1 307 ? -3.105 -5.933 5.962 1.00 22.59 ? 307 MET A C 1 ATOM 2420 O O . MET A 1 307 ? -4.245 -5.769 6.398 1.00 21.90 ? 307 MET A O 1 ATOM 2421 C CB . MET A 1 307 ? -1.109 -6.535 7.408 1.00 22.43 ? 307 MET A CB 1 ATOM 2422 C CG . MET A 1 307 ? -1.630 -5.785 8.659 1.00 22.15 ? 307 MET A CG 1 ATOM 2423 S SD . MET A 1 307 ? -0.259 -5.125 9.594 1.00 24.65 ? 307 MET A SD 1 ATOM 2424 C CE . MET A 1 307 ? 0.335 -6.612 10.370 1.00 22.36 ? 307 MET A CE 1 ATOM 2425 N N . ARG A 1 308 ? -2.573 -5.169 5.002 1.00 22.81 ? 308 ARG A N 1 ATOM 2426 C CA . ARG A 1 308 ? -3.231 -4.013 4.395 1.00 24.71 ? 308 ARG A CA 1 ATOM 2427 C C . ARG A 1 308 ? -4.548 -4.446 3.705 1.00 23.96 ? 308 ARG A C 1 ATOM 2428 O O . ARG A 1 308 ? -5.558 -3.732 3.801 1.00 22.70 ? 308 ARG A O 1 ATOM 2429 C CB . ARG A 1 308 ? -2.168 -3.326 3.479 1.00 24.59 ? 308 ARG A CB 1 ATOM 2430 C CG . ARG A 1 308 ? -2.490 -2.191 2.563 1.00 29.83 ? 308 ARG A CG 1 ATOM 2431 C CD . ARG A 1 308 ? -1.142 -1.745 1.887 1.00 29.27 ? 308 ARG A CD 1 ATOM 2432 N NE . ARG A 1 308 ? -0.541 -0.566 2.523 1.00 37.04 ? 308 ARG A NE 1 ATOM 2433 C CZ . ARG A 1 308 ? 0.755 -0.237 2.469 1.00 39.08 ? 308 ARG A CZ 1 ATOM 2434 N NH1 . ARG A 1 308 ? 1.646 -1.013 1.860 1.00 38.82 ? 308 ARG A NH1 1 ATOM 2435 N NH2 . ARG A 1 308 ? 1.175 0.873 3.049 1.00 40.44 ? 308 ARG A NH2 1 ATOM 2436 N N . GLU A 1 309 ? -4.563 -5.626 3.073 1.00 23.13 ? 309 GLU A N 1 ATOM 2437 C CA . GLU A 1 309 ? -5.778 -6.193 2.455 1.00 24.18 ? 309 GLU A CA 1 ATOM 2438 C C . GLU A 1 309 ? -6.864 -6.511 3.493 1.00 22.33 ? 309 GLU A C 1 ATOM 2439 O O . GLU A 1 309 ? -8.048 -6.260 3.269 1.00 21.76 ? 309 GLU A O 1 ATOM 2440 C CB . GLU A 1 309 ? -5.472 -7.471 1.650 1.00 24.25 ? 309 GLU A CB 1 ATOM 2441 C CG . GLU A 1 309 ? -6.719 -8.070 0.916 1.00 25.67 ? 309 GLU A CG 1 ATOM 2442 C CD . GLU A 1 309 ? -6.410 -9.361 0.154 1.00 29.41 ? 309 GLU A CD 1 ATOM 2443 O OE1 . GLU A 1 309 ? -5.193 -9.686 -0.014 1.00 35.57 ? 309 GLU A OE1 1 ATOM 2444 O OE2 . GLU A 1 309 ? -7.385 -10.069 -0.226 1.00 33.88 ? 309 GLU A OE2 1 ATOM 2445 N N . VAL A 1 310 ? -6.451 -7.097 4.609 1.00 20.80 ? 310 VAL A N 1 ATOM 2446 C CA . VAL A 1 310 ? -7.363 -7.359 5.719 1.00 19.86 ? 310 VAL A CA 1 ATOM 2447 C C . VAL A 1 310 ? -7.917 -6.064 6.304 1.00 19.20 ? 310 VAL A C 1 ATOM 2448 O O . VAL A 1 310 ? -9.134 -5.955 6.491 1.00 19.16 ? 310 VAL A O 1 ATOM 2449 C CB . VAL A 1 310 ? -6.690 -8.240 6.814 1.00 19.57 ? 310 VAL A CB 1 ATOM 2450 C CG1 . VAL A 1 310 ? -7.555 -8.313 8.080 1.00 19.89 ? 310 VAL A CG1 1 ATOM 2451 C CG2 . VAL A 1 310 ? -6.440 -9.634 6.258 1.00 19.12 ? 310 VAL A CG2 1 ATOM 2452 N N . VAL A 1 311 ? -7.034 -5.098 6.607 1.00 18.89 ? 311 VAL A N 1 ATOM 2453 C CA . VAL A 1 311 ? -7.439 -3.788 7.132 1.00 19.53 ? 311 VAL A CA 1 ATOM 2454 C C . VAL A 1 311 ? -8.486 -3.187 6.194 1.00 20.17 ? 311 VAL A C 1 ATOM 2455 O O . VAL A 1 311 ? -9.546 -2.752 6.640 1.00 19.49 ? 311 VAL A O 1 ATOM 2456 C CB . VAL A 1 311 ? -6.248 -2.777 7.274 1.00 19.48 ? 311 VAL A CB 1 ATOM 2457 C CG1 . VAL A 1 311 ? -6.754 -1.370 7.658 1.00 21.07 ? 311 VAL A CG1 1 ATOM 2458 C CG2 . VAL A 1 311 ? -5.236 -3.229 8.319 1.00 18.56 ? 311 VAL A CG2 1 ATOM 2459 N N . GLU A 1 312 ? -8.195 -3.177 4.896 1.00 20.11 ? 312 GLU A N 1 ATOM 2460 C CA . GLU A 1 312 ? -9.081 -2.505 3.965 1.00 22.38 ? 312 GLU A CA 1 ATOM 2461 C C . GLU A 1 312 ? -10.466 -3.133 3.794 1.00 21.17 ? 312 GLU A C 1 ATOM 2462 O O . GLU A 1 312 ? -11.461 -2.397 3.720 1.00 21.21 ? 312 GLU A O 1 ATOM 2463 C CB . GLU A 1 312 ? -8.356 -2.230 2.647 1.00 23.89 ? 312 GLU A CB 1 ATOM 2464 C CG . GLU A 1 312 ? -7.326 -1.100 2.870 1.00 29.28 ? 312 GLU A CG 1 ATOM 2465 C CD . GLU A 1 312 ? -7.976 0.226 3.339 1.00 38.02 ? 312 GLU A CD 1 ATOM 2466 O OE1 . GLU A 1 312 ? -8.760 0.827 2.543 1.00 40.80 ? 312 GLU A OE1 1 ATOM 2467 O OE2 . GLU A 1 312 ? -7.695 0.663 4.494 1.00 38.89 ? 312 GLU A OE2 1 ATOM 2468 N N . ARG A 1 313 ? -10.558 -4.462 3.778 1.00 20.15 ? 313 ARG A N 1 ATOM 2469 C CA . ARG A 1 313 ? -11.895 -5.094 3.629 1.00 20.44 ? 313 ARG A CA 1 ATOM 2470 C C . ARG A 1 313 ? -12.790 -4.893 4.869 1.00 19.65 ? 313 ARG A C 1 ATOM 2471 O O . ARG A 1 313 ? -14.027 -4.728 4.756 1.00 19.98 ? 313 ARG A O 1 ATOM 2472 C CB . ARG A 1 313 ? -11.813 -6.573 3.214 1.00 20.61 ? 313 ARG A CB 1 ATOM 2473 C CG . ARG A 1 313 ? -11.170 -7.510 4.238 1.00 21.44 ? 313 ARG A CG 1 ATOM 2474 C CD . ARG A 1 313 ? -11.430 -8.939 3.834 1.00 22.37 ? 313 ARG A CD 1 ATOM 2475 N NE . ARG A 1 313 ? -10.719 -9.862 4.705 1.00 21.93 ? 313 ARG A NE 1 ATOM 2476 C CZ . ARG A 1 313 ? -9.806 -10.738 4.284 1.00 24.06 ? 313 ARG A CZ 1 ATOM 2477 N NH1 . ARG A 1 313 ? -9.508 -10.840 2.990 1.00 27.12 ? 313 ARG A NH1 1 ATOM 2478 N NH2 . ARG A 1 313 ? -9.218 -11.542 5.157 1.00 22.59 ? 313 ARG A NH2 1 ATOM 2479 N N . ASN A 1 314 ? -12.182 -4.877 6.050 1.00 19.12 ? 314 ASN A N 1 ATOM 2480 C CA . ASN A 1 314 ? -12.947 -4.500 7.271 1.00 19.61 ? 314 ASN A CA 1 ATOM 2481 C C . ASN A 1 314 ? -13.352 -3.037 7.357 1.00 20.20 ? 314 ASN A C 1 ATOM 2482 O O . ASN A 1 314 ? -14.461 -2.727 7.791 1.00 20.00 ? 314 ASN A O 1 ATOM 2483 C CB . ASN A 1 314 ? -12.262 -5.010 8.536 1.00 19.59 ? 314 ASN A CB 1 ATOM 2484 C CG . ASN A 1 314 ? -12.274 -6.517 8.604 1.00 19.16 ? 314 ASN A CG 1 ATOM 2485 O OD1 . ASN A 1 314 ? -13.245 -7.112 9.071 1.00 17.42 ? 314 ASN A OD1 1 ATOM 2486 N ND2 . ASN A 1 314 ? -11.216 -7.156 8.086 1.00 15.35 ? 314 ASN A ND2 1 ATOM 2487 N N . ARG A 1 315 ? -12.470 -2.134 6.931 1.00 20.44 ? 315 ARG A N 1 ATOM 2488 C CA . ARG A 1 315 ? -12.816 -0.712 6.775 1.00 20.28 ? 315 ARG A CA 1 ATOM 2489 C C . ARG A 1 315 ? -13.896 -0.502 5.698 1.00 21.28 ? 315 ARG A C 1 ATOM 2490 O O . ARG A 1 315 ? -14.819 0.288 5.910 1.00 21.71 ? 315 ARG A O 1 ATOM 2491 C CB . ARG A 1 315 ? -11.559 0.130 6.460 1.00 20.27 ? 315 ARG A CB 1 ATOM 2492 C CG . ARG A 1 315 ? -10.619 0.301 7.669 1.00 19.89 ? 315 ARG A CG 1 ATOM 2493 C CD . ARG A 1 315 ? -9.576 1.374 7.454 1.00 21.20 ? 315 ARG A CD 1 ATOM 2494 N NE . ARG A 1 315 ? -10.183 2.686 7.464 1.00 26.30 ? 315 ARG A NE 1 ATOM 2495 C CZ . ARG A 1 315 ? -10.388 3.436 6.390 1.00 31.46 ? 315 ARG A CZ 1 ATOM 2496 N NH1 . ARG A 1 315 ? -10.005 3.015 5.187 1.00 32.96 ? 315 ARG A NH1 1 ATOM 2497 N NH2 . ARG A 1 315 ? -10.986 4.616 6.527 1.00 35.08 ? 315 ARG A NH2 1 ATOM 2498 N N . ALA A 1 316 ? -13.794 -1.216 4.572 1.00 21.19 ? 316 ALA A N 1 ATOM 2499 C CA . ALA A 1 316 ? -14.825 -1.171 3.490 1.00 22.05 ? 316 ALA A CA 1 ATOM 2500 C C . ALA A 1 316 ? -16.204 -1.607 3.999 1.00 22.45 ? 316 ALA A C 1 ATOM 2501 O O . ALA A 1 316 ? -17.262 -1.083 3.575 1.00 22.48 ? 316 ALA A O 1 ATOM 2502 C CB . ALA A 1 316 ? -14.384 -2.042 2.275 1.00 21.77 ? 316 ALA A CB 1 ATOM 2503 N N . ALA A 1 317 ? -16.204 -2.545 4.939 1.00 21.52 ? 317 ALA A N 1 ATOM 2504 C CA . ALA A 1 317 ? -17.438 -3.026 5.550 1.00 21.14 ? 317 ALA A CA 1 ATOM 2505 C C . ALA A 1 317 ? -18.019 -2.086 6.629 1.00 20.32 ? 317 ALA A C 1 ATOM 2506 O O . ALA A 1 317 ? -19.055 -2.403 7.199 1.00 20.81 ? 317 ALA A O 1 ATOM 2507 C CB . ALA A 1 317 ? -17.186 -4.383 6.159 1.00 21.27 ? 317 ALA A CB 1 ATOM 2508 N N . GLN A 1 318 ? -17.342 -0.980 6.933 1.00 19.16 ? 318 GLN A N 1 ATOM 2509 C CA . GLN A 1 318 ? -17.724 -0.024 7.996 1.00 20.85 ? 318 GLN A CA 1 ATOM 2510 C C . GLN A 1 318 ? -17.773 -0.695 9.376 1.00 20.80 ? 318 GLN A C 1 ATOM 2511 O O . GLN A 1 318 ? -18.639 -0.416 10.208 1.00 23.01 ? 318 GLN A O 1 ATOM 2512 C CB . GLN A 1 318 ? -19.032 0.750 7.666 1.00 22.20 ? 318 GLN A CB 1 ATOM 2513 C CG . GLN A 1 318 ? -19.014 1.489 6.279 1.00 24.95 ? 318 GLN A CG 1 ATOM 2514 C CD . GLN A 1 318 ? -17.875 2.472 6.135 1.00 29.78 ? 318 GLN A CD 1 ATOM 2515 O OE1 . GLN A 1 318 ? -17.637 3.321 7.003 1.00 30.31 ? 318 GLN A OE1 1 ATOM 2516 N NE2 . GLN A 1 318 ? -17.120 2.333 5.045 1.00 31.14 ? 318 GLN A NE2 1 ATOM 2517 N N . LEU A 1 319 ? -16.826 -1.599 9.602 1.00 20.59 ? 319 LEU A N 1 ATOM 2518 C CA . LEU A 1 319 ? -16.709 -2.265 10.898 1.00 20.65 ? 319 LEU A CA 1 ATOM 2519 C C . LEU A 1 319 ? -16.195 -1.268 11.930 1.00 19.64 ? 319 LEU A C 1 ATOM 2520 O O . LEU A 1 319 ? -15.220 -0.556 11.685 1.00 19.75 ? 319 LEU A O 1 ATOM 2521 C CB . LEU A 1 319 ? -15.792 -3.490 10.789 1.00 20.27 ? 319 LEU A CB 1 ATOM 2522 C CG . LEU A 1 319 ? -15.875 -4.507 11.941 1.00 21.22 ? 319 LEU A CG 1 ATOM 2523 C CD1 . LEU A 1 319 ? -17.192 -5.310 11.923 1.00 21.33 ? 319 LEU A CD1 1 ATOM 2524 C CD2 . LEU A 1 319 ? -14.646 -5.424 11.949 1.00 19.54 ? 319 LEU A CD2 1 ATOM 2525 N N . PRO A 1 320 ? -16.862 -1.189 13.102 1.00 19.03 ? 320 PRO A N 1 ATOM 2526 C CA . PRO A 1 320 ? -16.235 -0.401 14.149 1.00 17.51 ? 320 PRO A CA 1 ATOM 2527 C C . PRO A 1 320 ? -14.882 -1.065 14.442 1.00 16.66 ? 320 PRO A C 1 ATOM 2528 O O . PRO A 1 320 ? -14.814 -2.282 14.627 1.00 16.43 ? 320 PRO A O 1 ATOM 2529 C CB . PRO A 1 320 ? -17.221 -0.520 15.302 1.00 17.96 ? 320 PRO A CB 1 ATOM 2530 C CG . PRO A 1 320 ? -18.555 -0.799 14.575 1.00 17.74 ? 320 PRO A CG 1 ATOM 2531 C CD . PRO A 1 320 ? -18.157 -1.750 13.526 1.00 18.05 ? 320 PRO A CD 1 ATOM 2532 N N . TYR A 1 321 ? -13.804 -0.296 14.413 1.00 15.94 ? 321 TYR A N 1 ATOM 2533 C CA . TYR A 1 321 ? -12.477 -0.937 14.278 1.00 15.57 ? 321 TYR A CA 1 ATOM 2534 C C . TYR A 1 321 ? -11.393 0.073 14.591 1.00 16.23 ? 321 TYR A C 1 ATOM 2535 O O . TYR A 1 321 ? -11.026 0.905 13.752 1.00 17.06 ? 321 TYR A O 1 ATOM 2536 C CB . TYR A 1 321 ? -12.390 -1.552 12.860 1.00 15.59 ? 321 TYR A CB 1 ATOM 2537 C CG . TYR A 1 321 ? -11.060 -2.090 12.292 1.00 16.49 ? 321 TYR A CG 1 ATOM 2538 C CD1 . TYR A 1 321 ? -10.027 -2.542 13.106 1.00 16.32 ? 321 TYR A CD1 1 ATOM 2539 C CD2 . TYR A 1 321 ? -10.918 -2.210 10.904 1.00 17.79 ? 321 TYR A CD2 1 ATOM 2540 C CE1 . TYR A 1 321 ? -8.801 -3.056 12.528 1.00 13.23 ? 321 TYR A CE1 1 ATOM 2541 C CE2 . TYR A 1 321 ? -9.759 -2.713 10.326 1.00 19.18 ? 321 TYR A CE2 1 ATOM 2542 C CZ . TYR A 1 321 ? -8.712 -3.127 11.142 1.00 15.63 ? 321 TYR A CZ 1 ATOM 2543 O OH . TYR A 1 321 ? -7.615 -3.627 10.550 1.00 19.29 ? 321 TYR A OH 1 ATOM 2544 N N . ASP A 1 322 ? -10.904 0.031 15.830 1.00 14.89 ? 322 ASP A N 1 ATOM 2545 C CA . ASP A 1 322 ? -10.008 1.076 16.301 1.00 15.22 ? 322 ASP A CA 1 ATOM 2546 C C . ASP A 1 322 ? -8.537 0.720 16.193 1.00 15.17 ? 322 ASP A C 1 ATOM 2547 O O . ASP A 1 322 ? -7.672 1.623 15.997 1.00 14.56 ? 322 ASP A O 1 ATOM 2548 C CB . ASP A 1 322 ? -10.331 1.447 17.754 1.00 14.97 ? 322 ASP A CB 1 ATOM 2549 C CG . ASP A 1 322 ? -11.282 2.611 17.834 1.00 18.26 ? 322 ASP A CG 1 ATOM 2550 O OD1 . ASP A 1 322 ? -10.813 3.748 18.111 1.00 18.27 ? 322 ASP A OD1 1 ATOM 2551 O OD2 . ASP A 1 322 ? -12.481 2.370 17.530 1.00 17.90 ? 322 ASP A OD2 1 ATOM 2552 N N . VAL A 1 323 ? -8.244 -0.572 16.361 1.00 14.30 ? 323 VAL A N 1 ATOM 2553 C CA . VAL A 1 323 ? -6.863 -0.956 16.594 1.00 13.55 ? 323 VAL A CA 1 ATOM 2554 C C . VAL A 1 323 ? -6.446 -2.108 15.708 1.00 13.78 ? 323 VAL A C 1 ATOM 2555 O O . VAL A 1 323 ? -7.155 -3.094 15.581 1.00 12.92 ? 323 VAL A O 1 ATOM 2556 C CB . VAL A 1 323 ? -6.620 -1.336 18.103 1.00 13.17 ? 323 VAL A CB 1 ATOM 2557 C CG1 . VAL A 1 323 ? -5.112 -1.387 18.418 1.00 14.27 ? 323 VAL A CG1 1 ATOM 2558 C CG2 . VAL A 1 323 ? -7.273 -0.335 19.025 1.00 9.98 ? 323 VAL A CG2 1 ATOM 2559 N N . GLN A 1 324 ? -5.263 -1.984 15.100 1.00 13.69 ? 324 GLN A N 1 ATOM 2560 C CA . GLN A 1 324 ? -4.705 -3.086 14.339 1.00 14.18 ? 324 GLN A CA 1 ATOM 2561 C C . GLN A 1 324 ? -3.467 -3.557 15.098 1.00 14.32 ? 324 GLN A C 1 ATOM 2562 O O . GLN A 1 324 ? -2.666 -2.723 15.501 1.00 13.65 ? 324 GLN A O 1 ATOM 2563 C CB . GLN A 1 324 ? -4.330 -2.607 12.921 1.00 14.48 ? 324 GLN A CB 1 ATOM 2564 C CG . GLN A 1 324 ? -3.731 -3.706 12.020 1.00 14.43 ? 324 GLN A CG 1 ATOM 2565 C CD . GLN A 1 324 ? -4.576 -4.996 11.892 1.00 16.66 ? 324 GLN A CD 1 ATOM 2566 O OE1 . GLN A 1 324 ? -5.765 -4.952 11.611 1.00 18.24 ? 324 GLN A OE1 1 ATOM 2567 N NE2 . GLN A 1 324 ? -3.923 -6.147 12.039 1.00 15.28 ? 324 GLN A NE2 1 ATOM 2568 N N . HIS A 1 325 ? -3.325 -4.875 15.307 1.00 15.36 ? 325 HIS A N 1 ATOM 2569 C CA . HIS A 1 325 ? -2.118 -5.418 15.985 1.00 16.43 ? 325 HIS A CA 1 ATOM 2570 C C . HIS A 1 325 ? -1.191 -6.023 14.919 1.00 15.94 ? 325 HIS A C 1 ATOM 2571 O O . HIS A 1 325 ? -1.630 -6.517 13.881 1.00 16.52 ? 325 HIS A O 1 ATOM 2572 C CB . HIS A 1 325 ? -2.461 -6.473 17.066 1.00 17.47 ? 325 HIS A CB 1 ATOM 2573 C CG . HIS A 1 325 ? -3.239 -5.948 18.248 1.00 16.76 ? 325 HIS A CG 1 ATOM 2574 N ND1 . HIS A 1 325 ? -3.029 -6.400 19.530 1.00 18.26 ? 325 HIS A ND1 1 ATOM 2575 C CD2 . HIS A 1 325 ? -4.197 -4.995 18.345 1.00 15.15 ? 325 HIS A CD2 1 ATOM 2576 C CE1 . HIS A 1 325 ? -3.824 -5.757 20.365 1.00 18.96 ? 325 HIS A CE1 1 ATOM 2577 N NE2 . HIS A 1 325 ? -4.547 -4.901 19.669 1.00 15.15 ? 325 HIS A NE2 1 ATOM 2578 N N . ALA A 1 326 ? 0.106 -5.896 15.139 1.00 16.27 ? 326 ALA A N 1 ATOM 2579 C CA . ALA A 1 326 ? 1.076 -6.443 14.214 1.00 16.34 ? 326 ALA A CA 1 ATOM 2580 C C . ALA A 1 326 ? 1.839 -7.436 15.076 1.00 15.98 ? 326 ALA A C 1 ATOM 2581 O O . ALA A 1 326 ? 2.408 -7.042 16.085 1.00 15.93 ? 326 ALA A O 1 ATOM 2582 C CB . ALA A 1 326 ? 2.035 -5.309 13.689 1.00 15.99 ? 326 ALA A CB 1 ATOM 2583 N N . ASP A 1 327 ? 1.795 -8.702 14.690 1.00 16.14 ? 327 ASP A N 1 ATOM 2584 C CA . ASP A 1 327 ? 2.420 -9.822 15.423 1.00 17.49 ? 327 ASP A CA 1 ATOM 2585 C C . ASP A 1 327 ? 3.847 -9.997 14.880 1.00 18.26 ? 327 ASP A C 1 ATOM 2586 O O . ASP A 1 327 ? 4.336 -9.138 14.139 1.00 18.37 ? 327 ASP A O 1 ATOM 2587 C CB . ASP A 1 327 ? 1.589 -11.089 15.173 1.00 17.86 ? 327 ASP A CB 1 ATOM 2588 C CG . ASP A 1 327 ? 1.730 -12.132 16.259 1.00 19.57 ? 327 ASP A CG 1 ATOM 2589 O OD1 . ASP A 1 327 ? 2.799 -12.256 16.907 1.00 22.51 ? 327 ASP A OD1 1 ATOM 2590 O OD2 . ASP A 1 327 ? 0.748 -12.872 16.435 1.00 20.36 ? 327 ASP A OD2 1 ATOM 2591 N N . ILE A 1 328 ? 4.529 -11.083 15.237 1.00 18.50 ? 328 ILE A N 1 ATOM 2592 C CA . ILE A 1 328 ? 5.976 -11.151 14.973 1.00 19.18 ? 328 ILE A CA 1 ATOM 2593 C C . ILE A 1 328 ? 6.358 -11.189 13.511 1.00 19.77 ? 328 ILE A C 1 ATOM 2594 O O . ILE A 1 328 ? 7.541 -10.975 13.187 1.00 20.76 ? 328 ILE A O 1 ATOM 2595 C CB . ILE A 1 328 ? 6.666 -12.330 15.724 1.00 18.53 ? 328 ILE A CB 1 ATOM 2596 C CG1 . ILE A 1 328 ? 5.999 -13.678 15.357 1.00 17.17 ? 328 ILE A CG1 1 ATOM 2597 C CG2 . ILE A 1 328 ? 6.653 -12.041 17.207 1.00 18.97 ? 328 ILE A CG2 1 ATOM 2598 C CD1 . ILE A 1 328 ? 6.663 -14.910 16.059 1.00 17.73 ? 328 ILE A CD1 1 ATOM 2599 N N . ASP A 1 329 ? 5.379 -11.412 12.626 1.00 19.53 ? 329 ASP A N 1 ATOM 2600 C CA . ASP A 1 329 ? 5.660 -11.338 11.183 1.00 19.96 ? 329 ASP A CA 1 ATOM 2601 C C . ASP A 1 329 ? 6.153 -9.951 10.704 1.00 19.06 ? 329 ASP A C 1 ATOM 2602 O O . ASP A 1 329 ? 6.822 -9.878 9.673 1.00 18.81 ? 329 ASP A O 1 ATOM 2603 C CB . ASP A 1 329 ? 4.539 -11.946 10.304 1.00 20.87 ? 329 ASP A CB 1 ATOM 2604 C CG . ASP A 1 329 ? 3.136 -11.500 10.719 1.00 24.02 ? 329 ASP A CG 1 ATOM 2605 O OD1 . ASP A 1 329 ? 2.830 -11.508 11.929 1.00 25.78 ? 329 ASP A OD1 1 ATOM 2606 O OD2 . ASP A 1 329 ? 2.320 -11.169 9.828 1.00 27.13 ? 329 ASP A OD2 1 ATOM 2607 N N . TYR A 1 330 ? 5.898 -8.865 11.455 1.00 17.76 ? 330 TYR A N 1 ATOM 2608 C CA . TYR A 1 330 ? 6.376 -7.537 11.006 1.00 17.83 ? 330 TYR A CA 1 ATOM 2609 C C . TYR A 1 330 ? 7.882 -7.432 11.131 1.00 17.57 ? 330 TYR A C 1 ATOM 2610 O O . TYR A 1 330 ? 8.509 -6.624 10.441 1.00 17.96 ? 330 TYR A O 1 ATOM 2611 C CB . TYR A 1 330 ? 5.690 -6.351 11.717 1.00 18.03 ? 330 TYR A CB 1 ATOM 2612 C CG . TYR A 1 330 ? 6.164 -6.056 13.119 1.00 17.30 ? 330 TYR A CG 1 ATOM 2613 C CD1 . TYR A 1 330 ? 7.343 -5.352 13.363 1.00 17.95 ? 330 TYR A CD1 1 ATOM 2614 C CD2 . TYR A 1 330 ? 5.407 -6.445 14.207 1.00 18.96 ? 330 TYR A CD2 1 ATOM 2615 C CE1 . TYR A 1 330 ? 7.767 -5.090 14.646 1.00 17.49 ? 330 TYR A CE1 1 ATOM 2616 C CE2 . TYR A 1 330 ? 5.828 -6.210 15.491 1.00 17.56 ? 330 TYR A CE2 1 ATOM 2617 C CZ . TYR A 1 330 ? 6.988 -5.518 15.713 1.00 16.51 ? 330 TYR A CZ 1 ATOM 2618 O OH . TYR A 1 330 ? 7.386 -5.260 16.997 1.00 16.61 ? 330 TYR A OH 1 ATOM 2619 N N . MET A 1 331 ? 8.445 -8.240 12.020 1.00 17.30 ? 331 MET A N 1 ATOM 2620 C CA . MET A 1 331 ? 9.853 -8.130 12.407 1.00 18.04 ? 331 MET A CA 1 ATOM 2621 C C . MET A 1 331 ? 10.780 -8.675 11.314 1.00 18.34 ? 331 MET A C 1 ATOM 2622 O O . MET A 1 331 ? 10.367 -9.453 10.469 1.00 19.25 ? 331 MET A O 1 ATOM 2623 C CB . MET A 1 331 ? 10.120 -8.867 13.717 1.00 17.00 ? 331 MET A CB 1 ATOM 2624 C CG . MET A 1 331 ? 9.282 -8.386 14.956 1.00 16.94 ? 331 MET A CG 1 ATOM 2625 S SD . MET A 1 331 ? 9.512 -9.425 16.369 1.00 19.48 ? 331 MET A SD 1 ATOM 2626 C CE . MET A 1 331 ? 8.500 -8.543 17.613 1.00 14.36 ? 331 MET A CE 1 ATOM 2627 N N . ASP A 1 332 ? 12.049 -8.276 11.370 1.00 19.63 ? 332 ASP A N 1 ATOM 2628 C CA . ASP A 1 332 ? 13.097 -8.871 10.519 1.00 20.87 ? 332 ASP A CA 1 ATOM 2629 C C . ASP A 1 332 ? 13.564 -10.146 11.204 1.00 19.56 ? 332 ASP A C 1 ATOM 2630 O O . ASP A 1 332 ? 14.269 -10.111 12.231 1.00 18.95 ? 332 ASP A O 1 ATOM 2631 C CB . ASP A 1 332 ? 14.257 -7.887 10.344 1.00 20.87 ? 332 ASP A CB 1 ATOM 2632 C CG . ASP A 1 332 ? 15.301 -8.373 9.328 1.00 26.58 ? 332 ASP A CG 1 ATOM 2633 O OD1 . ASP A 1 332 ? 15.299 -9.559 8.951 1.00 29.89 ? 332 ASP A OD1 1 ATOM 2634 O OD2 . ASP A 1 332 ? 16.144 -7.545 8.949 1.00 31.90 ? 332 ASP A OD2 1 ATOM 2635 N N . GLU A 1 333 ? 13.122 -11.276 10.665 1.00 20.09 ? 333 GLU A N 1 ATOM 2636 C CA . GLU A 1 333 ? 13.418 -12.605 11.223 1.00 21.14 ? 333 GLU A CA 1 ATOM 2637 C C . GLU A 1 333 ? 13.027 -12.737 12.711 1.00 20.47 ? 333 GLU A C 1 ATOM 2638 O O . GLU A 1 333 ? 13.786 -13.252 13.536 1.00 19.45 ? 333 GLU A O 1 ATOM 2639 C CB . GLU A 1 333 ? 14.892 -13.014 10.950 1.00 22.52 ? 333 GLU A CB 1 ATOM 2640 C CG . GLU A 1 333 ? 15.280 -12.855 9.458 1.00 27.84 ? 333 GLU A CG 1 ATOM 2641 C CD . GLU A 1 333 ? 14.892 -14.022 8.554 1.00 36.83 ? 333 GLU A CD 1 ATOM 2642 O OE1 . GLU A 1 333 ? 14.176 -14.957 8.993 1.00 38.81 ? 333 GLU A OE1 1 ATOM 2643 O OE2 . GLU A 1 333 ? 15.327 -14.010 7.366 1.00 41.41 ? 333 GLU A OE2 1 ATOM 2644 N N . ARG A 1 334 ? 11.823 -12.242 13.038 1.00 19.58 ? 334 ARG A N 1 ATOM 2645 C CA . ARG A 1 334 ? 11.255 -12.410 14.381 1.00 19.29 ? 334 ARG A CA 1 ATOM 2646 C C . ARG A 1 334 ? 12.058 -11.766 15.538 1.00 18.98 ? 334 ARG A C 1 ATOM 2647 O O . ARG A 1 334 ? 11.956 -12.176 16.697 1.00 19.20 ? 334 ARG A O 1 ATOM 2648 C CB . ARG A 1 334 ? 10.895 -13.887 14.614 1.00 18.87 ? 334 ARG A CB 1 ATOM 2649 C CG . ARG A 1 334 ? 9.895 -14.386 13.570 1.00 20.86 ? 334 ARG A CG 1 ATOM 2650 C CD . ARG A 1 334 ? 9.545 -15.878 13.702 1.00 22.38 ? 334 ARG A CD 1 ATOM 2651 N NE . ARG A 1 334 ? 8.309 -16.191 12.984 1.00 26.12 ? 334 ARG A NE 1 ATOM 2652 C CZ . ARG A 1 334 ? 7.631 -17.327 13.122 1.00 28.55 ? 334 ARG A CZ 1 ATOM 2653 N NH1 . ARG A 1 334 ? 8.076 -18.272 13.942 1.00 30.73 ? 334 ARG A NH1 1 ATOM 2654 N NH2 . ARG A 1 334 ? 6.524 -17.520 12.439 1.00 29.62 ? 334 ARG A NH2 1 ATOM 2655 N N . ARG A 1 335 ? 12.843 -10.735 15.212 1.00 19.16 ? 335 ARG A N 1 ATOM 2656 C CA . ARG A 1 335 ? 13.615 -9.984 16.210 1.00 19.11 ? 335 ARG A CA 1 ATOM 2657 C C . ARG A 1 335 ? 12.988 -8.653 16.570 1.00 19.02 ? 335 ARG A C 1 ATOM 2658 O O . ARG A 1 335 ? 12.610 -7.878 15.670 1.00 20.28 ? 335 ARG A O 1 ATOM 2659 C CB . ARG A 1 335 ? 15.032 -9.716 15.682 1.00 20.43 ? 335 ARG A CB 1 ATOM 2660 C CG . ARG A 1 335 ? 15.819 -10.979 15.517 1.00 20.12 ? 335 ARG A CG 1 ATOM 2661 C CD . ARG A 1 335 ? 17.219 -10.674 15.041 1.00 25.06 ? 335 ARG A CD 1 ATOM 2662 N NE . ARG A 1 335 ? 17.180 -10.121 13.695 1.00 26.60 ? 335 ARG A NE 1 ATOM 2663 C CZ . ARG A 1 335 ? 18.229 -9.597 13.077 1.00 31.84 ? 335 ARG A CZ 1 ATOM 2664 N NH1 . ARG A 1 335 ? 19.413 -9.576 13.681 1.00 29.93 ? 335 ARG A NH1 1 ATOM 2665 N NH2 . ARG A 1 335 ? 18.094 -9.117 11.840 1.00 31.12 ? 335 ARG A NH2 1 ATOM 2666 N N . ASP A 1 336 ? 12.886 -8.379 17.875 1.00 20.04 ? 336 ASP A N 1 ATOM 2667 C CA . ASP A 1 336 ? 12.305 -7.113 18.392 1.00 19.54 ? 336 ASP A CA 1 ATOM 2668 C C . ASP A 1 336 ? 13.022 -5.923 17.776 1.00 20.28 ? 336 ASP A C 1 ATOM 2669 O O . ASP A 1 336 ? 14.236 -5.988 17.524 1.00 20.02 ? 336 ASP A O 1 ATOM 2670 C CB . ASP A 1 336 ? 12.578 -6.943 19.878 1.00 18.71 ? 336 ASP A CB 1 ATOM 2671 C CG . ASP A 1 336 ? 11.697 -7.781 20.771 1.00 19.81 ? 336 ASP A CG 1 ATOM 2672 O OD1 . ASP A 1 336 ? 10.649 -8.307 20.317 1.00 21.18 ? 336 ASP A OD1 1 ATOM 2673 O OD2 . ASP A 1 336 ? 12.062 -7.835 21.978 1.00 20.30 ? 336 ASP A OD2 1 ATOM 2674 N N . PHE A 1 337 ? 12.285 -4.826 17.614 1.00 18.86 ? 337 PHE A N 1 ATOM 2675 C CA . PHE A 1 337 ? 12.824 -3.497 17.250 1.00 19.15 ? 337 PHE A CA 1 ATOM 2676 C C . PHE A 1 337 ? 13.449 -3.423 15.847 1.00 19.63 ? 337 PHE A C 1 ATOM 2677 O O . PHE A 1 337 ? 14.386 -2.647 15.614 1.00 20.11 ? 337 PHE A O 1 ATOM 2678 C CB . PHE A 1 337 ? 13.810 -2.960 18.303 1.00 18.45 ? 337 PHE A CB 1 ATOM 2679 C CG . PHE A 1 337 ? 13.328 -3.094 19.719 1.00 19.57 ? 337 PHE A CG 1 ATOM 2680 C CD1 . PHE A 1 337 ? 12.154 -2.451 20.136 1.00 19.75 ? 337 PHE A CD1 1 ATOM 2681 C CD2 . PHE A 1 337 ? 14.019 -3.900 20.635 1.00 16.01 ? 337 PHE A CD2 1 ATOM 2682 C CE1 . PHE A 1 337 ? 11.713 -2.582 21.467 1.00 16.53 ? 337 PHE A CE1 1 ATOM 2683 C CE2 . PHE A 1 337 ? 13.562 -4.053 21.961 1.00 18.84 ? 337 PHE A CE2 1 ATOM 2684 C CZ . PHE A 1 337 ? 12.391 -3.382 22.360 1.00 18.12 ? 337 PHE A CZ 1 ATOM 2685 N N . THR A 1 338 ? 12.920 -4.239 14.951 1.00 19.98 ? 338 THR A N 1 ATOM 2686 C CA . THR A 1 338 ? 13.230 -4.242 13.541 1.00 20.57 ? 338 THR A CA 1 ATOM 2687 C C . THR A 1 338 ? 11.911 -4.451 12.818 1.00 21.00 ? 338 THR A C 1 ATOM 2688 O O . THR A 1 338 ? 10.910 -4.882 13.411 1.00 20.39 ? 338 THR A O 1 ATOM 2689 C CB . THR A 1 338 ? 14.144 -5.436 13.189 1.00 20.51 ? 338 THR A CB 1 ATOM 2690 O OG1 . THR A 1 338 ? 13.434 -6.678 13.351 1.00 21.95 ? 338 THR A OG1 1 ATOM 2691 C CG2 . THR A 1 338 ? 15.400 -5.449 14.087 1.00 20.18 ? 338 THR A CG2 1 ATOM 2692 N N . TYR A 1 339 ? 11.894 -4.153 11.535 1.00 20.63 ? 339 TYR A N 1 ATOM 2693 C CA . TYR A 1 339 ? 10.847 -4.671 10.697 1.00 21.88 ? 339 TYR A CA 1 ATOM 2694 C C . TYR A 1 339 ? 11.445 -5.239 9.418 1.00 22.89 ? 339 TYR A C 1 ATOM 2695 O O . TYR A 1 339 ? 12.574 -4.860 9.031 1.00 22.58 ? 339 TYR A O 1 ATOM 2696 C CB . TYR A 1 339 ? 9.759 -3.630 10.450 1.00 23.04 ? 339 TYR A CB 1 ATOM 2697 C CG . TYR A 1 339 ? 10.094 -2.435 9.584 1.00 24.29 ? 339 TYR A CG 1 ATOM 2698 C CD1 . TYR A 1 339 ? 10.007 -2.514 8.192 1.00 24.90 ? 339 TYR A CD1 1 ATOM 2699 C CD2 . TYR A 1 339 ? 10.438 -1.222 10.147 1.00 24.33 ? 339 TYR A CD2 1 ATOM 2700 C CE1 . TYR A 1 339 ? 10.275 -1.408 7.390 1.00 23.89 ? 339 TYR A CE1 1 ATOM 2701 C CE2 . TYR A 1 339 ? 10.710 -0.107 9.352 1.00 25.59 ? 339 TYR A CE2 1 ATOM 2702 C CZ . TYR A 1 339 ? 10.614 -0.225 7.979 1.00 23.11 ? 339 TYR A CZ 1 ATOM 2703 O OH . TYR A 1 339 ? 10.863 0.856 7.195 1.00 27.60 ? 339 TYR A OH 1 ATOM 2704 N N . ASP A 1 340 ? 10.709 -6.155 8.796 1.00 22.64 ? 340 ASP A N 1 ATOM 2705 C CA . ASP A 1 340 ? 11.148 -6.847 7.589 1.00 24.72 ? 340 ASP A CA 1 ATOM 2706 C C . ASP A 1 340 ? 11.112 -5.860 6.415 1.00 24.84 ? 340 ASP A C 1 ATOM 2707 O O . ASP A 1 340 ? 10.056 -5.503 5.920 1.00 24.54 ? 340 ASP A O 1 ATOM 2708 C CB . ASP A 1 340 ? 10.239 -8.050 7.331 1.00 24.08 ? 340 ASP A CB 1 ATOM 2709 C CG . ASP A 1 340 ? 10.737 -8.951 6.210 1.00 26.59 ? 340 ASP A CG 1 ATOM 2710 O OD1 . ASP A 1 340 ? 11.409 -8.463 5.289 1.00 27.12 ? 340 ASP A OD1 1 ATOM 2711 O OD2 . ASP A 1 340 ? 10.419 -10.153 6.236 1.00 27.90 ? 340 ASP A OD2 1 ATOM 2712 N N . SER A 1 341 ? 12.289 -5.441 5.964 1.00 26.08 ? 341 SER A N 1 ATOM 2713 C CA . SER A 1 341 ? 12.414 -4.407 4.928 1.00 26.84 ? 341 SER A CA 1 ATOM 2714 C C . SER A 1 341 ? 11.920 -4.859 3.565 1.00 26.61 ? 341 SER A C 1 ATOM 2715 O O . SER A 1 341 ? 11.751 -4.036 2.679 1.00 27.40 ? 341 SER A O 1 ATOM 2716 C CB . SER A 1 341 ? 13.883 -4.014 4.794 1.00 27.14 ? 341 SER A CB 1 ATOM 2717 O OG . SER A 1 341 ? 14.585 -5.160 4.308 1.00 29.75 ? 341 SER A OG 1 ATOM 2718 N N . VAL A 1 342 ? 11.704 -6.161 3.380 1.00 26.60 ? 342 VAL A N 1 ATOM 2719 C CA . VAL A 1 342 ? 11.119 -6.689 2.139 1.00 26.40 ? 342 VAL A CA 1 ATOM 2720 C C . VAL A 1 342 ? 9.618 -6.957 2.301 1.00 25.91 ? 342 VAL A C 1 ATOM 2721 O O . VAL A 1 342 ? 8.787 -6.332 1.633 1.00 25.80 ? 342 VAL A O 1 ATOM 2722 C CB . VAL A 1 342 ? 11.911 -7.949 1.620 1.00 26.93 ? 342 VAL A CB 1 ATOM 2723 C CG1 . VAL A 1 342 ? 11.222 -8.640 0.456 1.00 27.26 ? 342 VAL A CG1 1 ATOM 2724 C CG2 . VAL A 1 342 ? 13.336 -7.533 1.218 1.00 27.79 ? 342 VAL A CG2 1 ATOM 2725 N N . ASP A 1 343 ? 9.250 -7.872 3.193 1.00 24.98 ? 343 ASP A N 1 ATOM 2726 C CA . ASP A 1 343 ? 7.815 -8.208 3.329 1.00 23.97 ? 343 ASP A CA 1 ATOM 2727 C C . ASP A 1 343 ? 6.987 -7.096 3.984 1.00 22.67 ? 343 ASP A C 1 ATOM 2728 O O . ASP A 1 343 ? 5.772 -7.018 3.755 1.00 22.07 ? 343 ASP A O 1 ATOM 2729 C CB . ASP A 1 343 ? 7.624 -9.509 4.099 1.00 24.66 ? 343 ASP A CB 1 ATOM 2730 C CG . ASP A 1 343 ? 7.988 -10.750 3.288 1.00 27.49 ? 343 ASP A CG 1 ATOM 2731 O OD1 . ASP A 1 343 ? 8.281 -10.653 2.075 1.00 31.53 ? 343 ASP A OD1 1 ATOM 2732 O OD2 . ASP A 1 343 ? 7.925 -11.845 3.880 1.00 31.45 ? 343 ASP A OD2 1 ATOM 2733 N N . PHE A 1 344 ? 7.633 -6.271 4.804 1.00 22.37 ? 344 PHE A N 1 ATOM 2734 C CA . PHE A 1 344 ? 6.981 -5.116 5.435 1.00 22.53 ? 344 PHE A CA 1 ATOM 2735 C C . PHE A 1 344 ? 7.606 -3.799 4.969 1.00 21.91 ? 344 PHE A C 1 ATOM 2736 O O . PHE A 1 344 ? 7.691 -2.830 5.710 1.00 21.47 ? 344 PHE A O 1 ATOM 2737 C CB . PHE A 1 344 ? 6.928 -5.261 6.961 1.00 21.90 ? 344 PHE A CB 1 ATOM 2738 C CG . PHE A 1 344 ? 5.827 -6.189 7.433 1.00 22.45 ? 344 PHE A CG 1 ATOM 2739 C CD1 . PHE A 1 344 ? 5.943 -7.575 7.279 1.00 22.41 ? 344 PHE A CD1 1 ATOM 2740 C CD2 . PHE A 1 344 ? 4.635 -5.668 7.972 1.00 22.59 ? 344 PHE A CD2 1 ATOM 2741 C CE1 . PHE A 1 344 ? 4.891 -8.441 7.680 1.00 20.70 ? 344 PHE A CE1 1 ATOM 2742 C CE2 . PHE A 1 344 ? 3.593 -6.518 8.376 1.00 20.85 ? 344 PHE A CE2 1 ATOM 2743 C CZ . PHE A 1 344 ? 3.713 -7.891 8.231 1.00 23.45 ? 344 PHE A CZ 1 ATOM 2744 N N . LYS A 1 345 ? 8.030 -3.774 3.708 1.00 23.34 ? 345 LYS A N 1 ATOM 2745 C CA . LYS A 1 345 ? 8.556 -2.540 3.098 1.00 24.20 ? 345 LYS A CA 1 ATOM 2746 C C . LYS A 1 345 ? 7.406 -1.536 3.054 1.00 23.59 ? 345 LYS A C 1 ATOM 2747 O O . LYS A 1 345 ? 6.289 -1.862 2.636 1.00 24.08 ? 345 LYS A O 1 ATOM 2748 C CB . LYS A 1 345 ? 9.069 -2.825 1.682 1.00 23.89 ? 345 LYS A CB 1 ATOM 2749 C CG . LYS A 1 345 ? 9.672 -1.595 0.955 1.00 27.57 ? 345 LYS A CG 1 ATOM 2750 C CD . LYS A 1 345 ? 9.903 -1.900 -0.548 1.00 26.50 ? 345 LYS A CD 1 ATOM 2751 C CE . LYS A 1 345 ? 10.156 -0.615 -1.336 1.00 33.74 ? 345 LYS A CE 1 ATOM 2752 N NZ . LYS A 1 345 ? 10.465 -0.887 -2.779 1.00 35.99 ? 345 LYS A NZ 1 ATOM 2753 N N . GLY A 1 346 ? 7.666 -0.323 3.494 1.00 24.00 ? 346 GLY A N 1 ATOM 2754 C CA . GLY A 1 346 ? 6.604 0.684 3.560 1.00 24.76 ? 346 GLY A CA 1 ATOM 2755 C C . GLY A 1 346 ? 5.761 0.624 4.824 1.00 25.25 ? 346 GLY A C 1 ATOM 2756 O O . GLY A 1 346 ? 4.662 1.222 4.889 1.00 25.17 ? 346 GLY A O 1 ATOM 2757 N N . PHE A 1 347 ? 6.264 -0.088 5.834 1.00 24.34 ? 347 PHE A N 1 ATOM 2758 C CA . PHE A 1 347 ? 5.624 -0.125 7.169 1.00 24.33 ? 347 PHE A CA 1 ATOM 2759 C C . PHE A 1 347 ? 5.327 1.296 7.708 1.00 23.81 ? 347 PHE A C 1 ATOM 2760 O O . PHE A 1 347 ? 4.189 1.541 8.134 1.00 23.01 ? 347 PHE A O 1 ATOM 2761 C CB . PHE A 1 347 ? 6.421 -1.010 8.157 1.00 24.60 ? 347 PHE A CB 1 ATOM 2762 C CG . PHE A 1 347 ? 5.617 -1.573 9.315 1.00 25.58 ? 347 PHE A CG 1 ATOM 2763 C CD1 . PHE A 1 347 ? 4.229 -1.757 9.235 1.00 25.46 ? 347 PHE A CD1 1 ATOM 2764 C CD2 . PHE A 1 347 ? 6.271 -1.978 10.470 1.00 25.31 ? 347 PHE A CD2 1 ATOM 2765 C CE1 . PHE A 1 347 ? 3.519 -2.305 10.318 1.00 25.26 ? 347 PHE A CE1 1 ATOM 2766 C CE2 . PHE A 1 347 ? 5.575 -2.508 11.559 1.00 26.56 ? 347 PHE A CE2 1 ATOM 2767 C CZ . PHE A 1 347 ? 4.194 -2.665 11.484 1.00 23.92 ? 347 PHE A CZ 1 ATOM 2768 N N . PRO A 1 348 ? 6.317 2.242 7.674 1.00 23.28 ? 348 PRO A N 1 ATOM 2769 C CA . PRO A 1 348 ? 6.000 3.590 8.144 1.00 22.85 ? 348 PRO A CA 1 ATOM 2770 C C . PRO A 1 348 ? 4.871 4.276 7.383 1.00 21.92 ? 348 PRO A C 1 ATOM 2771 O O . PRO A 1 348 ? 4.105 5.011 8.004 1.00 21.69 ? 348 PRO A O 1 ATOM 2772 C CB . PRO A 1 348 ? 7.326 4.344 7.975 1.00 23.28 ? 348 PRO A CB 1 ATOM 2773 C CG . PRO A 1 348 ? 8.367 3.228 8.087 1.00 23.63 ? 348 PRO A CG 1 ATOM 2774 C CD . PRO A 1 348 ? 7.748 2.140 7.304 1.00 23.33 ? 348 PRO A CD 1 ATOM 2775 N N . GLU A 1 349 ? 4.748 4.026 6.081 1.00 20.89 ? 349 GLU A N 1 ATOM 2776 C CA . GLU A 1 349 ? 3.652 4.621 5.300 1.00 22.90 ? 349 GLU A CA 1 ATOM 2777 C C . GLU A 1 349 ? 2.295 4.038 5.739 1.00 22.39 ? 349 GLU A C 1 ATOM 2778 O O . GLU A 1 349 ? 1.269 4.724 5.748 1.00 20.60 ? 349 GLU A O 1 ATOM 2779 C CB . GLU A 1 349 ? 3.861 4.411 3.800 1.00 22.89 ? 349 GLU A CB 1 ATOM 2780 C CG . GLU A 1 349 ? 5.201 5.016 3.264 1.00 26.00 ? 349 GLU A CG 1 ATOM 2781 C CD . GLU A 1 349 ? 5.762 4.319 2.014 1.00 27.12 ? 349 GLU A CD 1 ATOM 2782 O OE1 . GLU A 1 349 ? 4.980 3.974 1.109 1.00 33.60 ? 349 GLU A OE1 1 ATOM 2783 O OE2 . GLU A 1 349 ? 7.004 4.156 1.918 1.00 30.98 ? 349 GLU A OE2 1 ATOM 2784 N N . PHE A 1 350 ? 2.306 2.759 6.076 1.00 22.12 ? 350 PHE A N 1 ATOM 2785 C CA . PHE A 1 350 ? 1.072 2.052 6.503 1.00 21.05 ? 350 PHE A CA 1 ATOM 2786 C C . PHE A 1 350 ? 0.587 2.573 7.847 1.00 20.83 ? 350 PHE A C 1 ATOM 2787 O O . PHE A 1 350 ? -0.640 2.691 8.075 1.00 21.05 ? 350 PHE A O 1 ATOM 2788 C CB . PHE A 1 350 ? 1.335 0.551 6.609 1.00 21.65 ? 350 PHE A CB 1 ATOM 2789 C CG . PHE A 1 350 ? 0.240 -0.221 7.350 1.00 20.96 ? 350 PHE A CG 1 ATOM 2790 C CD1 . PHE A 1 350 ? -0.961 -0.509 6.731 1.00 24.97 ? 350 PHE A CD1 1 ATOM 2791 C CD2 . PHE A 1 350 ? 0.461 -0.680 8.652 1.00 22.10 ? 350 PHE A CD2 1 ATOM 2792 C CE1 . PHE A 1 350 ? -1.959 -1.229 7.397 1.00 23.15 ? 350 PHE A CE1 1 ATOM 2793 C CE2 . PHE A 1 350 ? -0.516 -1.430 9.328 1.00 21.19 ? 350 PHE A CE2 1 ATOM 2794 C CZ . PHE A 1 350 ? -1.736 -1.680 8.697 1.00 21.95 ? 350 PHE A CZ 1 ATOM 2795 N N . VAL A 1 351 ? 1.535 2.858 8.732 1.00 20.03 ? 351 VAL A N 1 ATOM 2796 C CA . VAL A 1 351 ? 1.247 3.472 10.035 1.00 20.47 ? 351 VAL A CA 1 ATOM 2797 C C . VAL A 1 351 ? 0.564 4.842 9.840 1.00 19.95 ? 351 VAL A C 1 ATOM 2798 O O . VAL A 1 351 ? -0.444 5.130 10.504 1.00 17.42 ? 351 VAL A O 1 ATOM 2799 C CB . VAL A 1 351 ? 2.507 3.523 10.943 1.00 21.29 ? 351 VAL A CB 1 ATOM 2800 C CG1 . VAL A 1 351 ? 2.225 4.232 12.267 1.00 22.97 ? 351 VAL A CG1 1 ATOM 2801 C CG2 . VAL A 1 351 ? 3.009 2.094 11.213 1.00 22.35 ? 351 VAL A CG2 1 ATOM 2802 N N . ASN A 1 352 ? 1.078 5.667 8.916 1.00 19.23 ? 352 ASN A N 1 ATOM 2803 C CA . ASN A 1 352 ? 0.388 6.933 8.563 1.00 19.05 ? 352 ASN A CA 1 ATOM 2804 C C . ASN A 1 352 ? -1.042 6.710 8.071 1.00 18.38 ? 352 ASN A C 1 ATOM 2805 O O . ASN A 1 352 ? -1.944 7.507 8.409 1.00 17.22 ? 352 ASN A O 1 ATOM 2806 C CB . ASN A 1 352 ? 1.132 7.694 7.466 1.00 18.65 ? 352 ASN A CB 1 ATOM 2807 C CG . ASN A 1 352 ? 2.380 8.354 7.971 1.00 21.93 ? 352 ASN A CG 1 ATOM 2808 O OD1 . ASN A 1 352 ? 2.684 8.314 9.168 1.00 22.01 ? 352 ASN A OD1 1 ATOM 2809 N ND2 . ASN A 1 352 ? 3.114 8.992 7.063 1.00 23.63 ? 352 ASN A ND2 1 ATOM 2810 N N . GLU A 1 353 ? -1.225 5.698 7.229 1.00 18.81 ? 353 GLU A N 1 ATOM 2811 C CA . GLU A 1 353 ? -2.592 5.326 6.737 1.00 20.81 ? 353 GLU A CA 1 ATOM 2812 C C . GLU A 1 353 ? -3.536 4.987 7.883 1.00 20.21 ? 353 GLU A C 1 ATOM 2813 O O . GLU A 1 353 ? -4.693 5.411 7.875 1.00 19.66 ? 353 GLU A O 1 ATOM 2814 C CB . GLU A 1 353 ? -2.558 4.146 5.750 1.00 21.03 ? 353 GLU A CB 1 ATOM 2815 C CG . GLU A 1 353 ? -1.925 4.501 4.410 1.00 23.96 ? 353 GLU A CG 1 ATOM 2816 C CD . GLU A 1 353 ? -1.535 3.311 3.557 1.00 26.00 ? 353 GLU A CD 1 ATOM 2817 O OE1 . GLU A 1 353 ? -1.544 2.145 4.041 1.00 30.02 ? 353 GLU A OE1 1 ATOM 2818 O OE2 . GLU A 1 353 ? -1.151 3.580 2.389 1.00 31.89 ? 353 GLU A OE2 1 ATOM 2819 N N . LEU A 1 354 ? -3.067 4.174 8.832 1.00 19.42 ? 354 LEU A N 1 ATOM 2820 C CA . LEU A 1 354 ? -3.899 3.813 9.998 1.00 18.64 ? 354 LEU A CA 1 ATOM 2821 C C . LEU A 1 354 ? -4.250 5.100 10.718 1.00 18.64 ? 354 LEU A C 1 ATOM 2822 O O . LEU A 1 354 ? -5.412 5.342 11.023 1.00 16.77 ? 354 LEU A O 1 ATOM 2823 C CB . LEU A 1 354 ? -3.148 2.874 10.980 1.00 18.61 ? 354 LEU A CB 1 ATOM 2824 C CG . LEU A 1 354 ? -2.981 1.401 10.607 1.00 17.95 ? 354 LEU A CG 1 ATOM 2825 C CD1 . LEU A 1 354 ? -2.103 0.742 11.700 1.00 17.68 ? 354 LEU A CD1 1 ATOM 2826 C CD2 . LEU A 1 354 ? -4.295 0.646 10.443 1.00 19.83 ? 354 LEU A CD2 1 ATOM 2827 N N . HIS A 1 355 ? -3.236 5.942 10.962 1.00 17.97 ? 355 HIS A N 1 ATOM 2828 C CA . HIS A 1 355 ? -3.440 7.152 11.746 1.00 18.86 ? 355 HIS A CA 1 ATOM 2829 C C . HIS A 1 355 ? -4.406 8.109 11.056 1.00 19.29 ? 355 HIS A C 1 ATOM 2830 O O . HIS A 1 355 ? -5.317 8.671 11.711 1.00 17.31 ? 355 HIS A O 1 ATOM 2831 C CB . HIS A 1 355 ? -2.098 7.816 12.072 1.00 19.56 ? 355 HIS A CB 1 ATOM 2832 C CG . HIS A 1 355 ? -1.322 7.070 13.112 1.00 20.74 ? 355 HIS A CG 1 ATOM 2833 N ND1 . HIS A 1 355 ? -0.002 7.324 13.393 1.00 19.50 ? 355 HIS A ND1 1 ATOM 2834 C CD2 . HIS A 1 355 ? -1.698 6.057 13.934 1.00 20.39 ? 355 HIS A CD2 1 ATOM 2835 C CE1 . HIS A 1 355 ? 0.404 6.512 14.358 1.00 19.47 ? 355 HIS A CE1 1 ATOM 2836 N NE2 . HIS A 1 355 ? -0.599 5.714 14.683 1.00 20.95 ? 355 HIS A NE2 1 ATOM 2837 N N . ASN A 1 356 ? -4.225 8.264 9.741 1.00 18.56 ? 356 ASN A N 1 ATOM 2838 C CA . ASN A 1 356 ? -5.149 9.088 8.944 1.00 20.10 ? 356 ASN A CA 1 ATOM 2839 C C . ASN A 1 356 ? -6.583 8.576 8.968 1.00 20.97 ? 356 ASN A C 1 ATOM 2840 O O . ASN A 1 356 ? -7.520 9.351 8.742 1.00 21.19 ? 356 ASN A O 1 ATOM 2841 C CB . ASN A 1 356 ? -4.703 9.147 7.479 1.00 20.99 ? 356 ASN A CB 1 ATOM 2842 C CG . ASN A 1 356 ? -5.414 10.233 6.707 1.00 21.54 ? 356 ASN A CG 1 ATOM 2843 O OD1 . ASN A 1 356 ? -5.587 11.324 7.214 1.00 24.85 ? 356 ASN A OD1 1 ATOM 2844 N ND2 . ASN A 1 356 ? -5.806 9.943 5.467 1.00 23.90 ? 356 ASN A ND2 1 ATOM 2845 N N . ASN A 1 357 ? -6.750 7.272 9.172 1.00 20.06 ? 357 ASN A N 1 ATOM 2846 C CA . ASN A 1 357 ? -8.089 6.655 9.231 1.00 21.47 ? 357 ASN A CA 1 ATOM 2847 C C . ASN A 1 357 ? -8.674 6.640 10.650 1.00 20.90 ? 357 ASN A C 1 ATOM 2848 O O . ASN A 1 357 ? -9.779 6.082 10.907 1.00 20.48 ? 357 ASN A O 1 ATOM 2849 C CB . ASN A 1 357 ? -8.042 5.246 8.619 1.00 22.52 ? 357 ASN A CB 1 ATOM 2850 C CG . ASN A 1 357 ? -7.742 5.261 7.099 1.00 26.11 ? 357 ASN A CG 1 ATOM 2851 O OD1 . ASN A 1 357 ? -7.094 4.370 6.598 1.00 30.47 ? 357 ASN A OD1 1 ATOM 2852 N ND2 . ASN A 1 357 ? -8.261 6.247 6.378 1.00 32.44 ? 357 ASN A ND2 1 ATOM 2853 N N . GLY A 1 358 ? -7.937 7.269 11.559 1.00 18.86 ? 358 GLY A N 1 ATOM 2854 C CA . GLY A 1 358 ? -8.300 7.375 12.970 1.00 19.18 ? 358 GLY A CA 1 ATOM 2855 C C . GLY A 1 358 ? -8.114 6.077 13.740 1.00 18.66 ? 358 GLY A C 1 ATOM 2856 O O . GLY A 1 358 ? -8.753 5.869 14.772 1.00 19.32 ? 358 GLY A O 1 ATOM 2857 N N . GLN A 1 359 ? -7.217 5.217 13.248 1.00 17.76 ? 359 GLN A N 1 ATOM 2858 C CA . GLN A 1 359 ? -6.895 3.963 13.916 1.00 16.19 ? 359 GLN A CA 1 ATOM 2859 C C . GLN A 1 359 ? -5.521 3.976 14.601 1.00 16.78 ? 359 GLN A C 1 ATOM 2860 O O . GLN A 1 359 ? -4.741 4.949 14.491 1.00 16.19 ? 359 GLN A O 1 ATOM 2861 C CB . GLN A 1 359 ? -6.974 2.818 12.922 1.00 16.95 ? 359 GLN A CB 1 ATOM 2862 C CG . GLN A 1 359 ? -8.355 2.625 12.315 1.00 18.15 ? 359 GLN A CG 1 ATOM 2863 C CD . GLN A 1 359 ? -8.291 1.653 11.207 1.00 20.01 ? 359 GLN A CD 1 ATOM 2864 O OE1 . GLN A 1 359 ? -7.613 1.887 10.190 1.00 21.95 ? 359 GLN A OE1 1 ATOM 2865 N NE2 . GLN A 1 359 ? -8.940 0.505 11.396 1.00 18.66 ? 359 GLN A NE2 1 ATOM 2866 N N . LYS A 1 360 ? -5.249 2.905 15.345 1.00 15.71 ? 360 LYS A N 1 ATOM 2867 C CA . LYS A 1 360 ? -4.065 2.817 16.175 1.00 15.48 ? 360 LYS A CA 1 ATOM 2868 C C . LYS A 1 360 ? -3.311 1.550 15.819 1.00 15.30 ? 360 LYS A C 1 ATOM 2869 O O . LYS A 1 360 ? -3.906 0.562 15.412 1.00 15.26 ? 360 LYS A O 1 ATOM 2870 C CB . LYS A 1 360 ? -4.438 2.811 17.664 1.00 16.54 ? 360 LYS A CB 1 ATOM 2871 C CG . LYS A 1 360 ? -5.312 4.051 18.095 1.00 18.54 ? 360 LYS A CG 1 ATOM 2872 C CD . LYS A 1 360 ? -4.456 5.338 18.109 1.00 19.70 ? 360 LYS A CD 1 ATOM 2873 C CE . LYS A 1 360 ? -5.273 6.557 18.521 1.00 22.12 ? 360 LYS A CE 1 ATOM 2874 N NZ . LYS A 1 360 ? -4.448 7.800 18.767 1.00 26.17 ? 360 LYS A NZ 1 ATOM 2875 N N . LEU A 1 361 ? -1.998 1.580 16.011 1.00 15.74 ? 361 LEU A N 1 ATOM 2876 C CA . LEU A 1 361 ? -1.183 0.393 15.770 1.00 16.00 ? 361 LEU A CA 1 ATOM 2877 C C . LEU A 1 361 ? -0.670 -0.087 17.107 1.00 15.07 ? 361 LEU A C 1 ATOM 2878 O O . LEU A 1 361 ? -0.101 0.681 17.855 1.00 16.11 ? 361 LEU A O 1 ATOM 2879 C CB . LEU A 1 361 ? 0.020 0.714 14.844 1.00 16.47 ? 361 LEU A CB 1 ATOM 2880 C CG . LEU A 1 361 ? 1.035 -0.443 14.726 1.00 16.67 ? 361 LEU A CG 1 ATOM 2881 C CD1 . LEU A 1 361 ? 0.417 -1.602 13.965 1.00 18.16 ? 361 LEU A CD1 1 ATOM 2882 C CD2 . LEU A 1 361 ? 2.333 0.057 14.047 1.00 17.20 ? 361 LEU A CD2 1 ATOM 2883 N N . VAL A 1 362 ? -0.821 -1.376 17.378 1.00 15.47 ? 362 VAL A N 1 ATOM 2884 C CA . VAL A 1 362 ? -0.252 -1.975 18.562 1.00 14.85 ? 362 VAL A CA 1 ATOM 2885 C C . VAL A 1 362 ? 0.731 -3.022 18.035 1.00 14.20 ? 362 VAL A C 1 ATOM 2886 O O . VAL A 1 362 ? 0.354 -3.858 17.231 1.00 14.49 ? 362 VAL A O 1 ATOM 2887 C CB . VAL A 1 362 ? -1.318 -2.639 19.468 1.00 15.72 ? 362 VAL A CB 1 ATOM 2888 C CG1 . VAL A 1 362 ? -0.614 -3.581 20.499 1.00 15.72 ? 362 VAL A CG1 1 ATOM 2889 C CG2 . VAL A 1 362 ? -2.105 -1.558 20.206 1.00 13.54 ? 362 VAL A CG2 1 ATOM 2890 N N . ILE A 1 363 ? 1.970 -2.952 18.485 1.00 14.61 ? 363 ILE A N 1 ATOM 2891 C CA . ILE A 1 363 ? 3.001 -3.926 18.082 1.00 16.39 ? 363 ILE A CA 1 ATOM 2892 C C . ILE A 1 363 ? 3.328 -4.917 19.187 1.00 15.14 ? 363 ILE A C 1 ATOM 2893 O O . ILE A 1 363 ? 3.384 -4.551 20.339 1.00 16.28 ? 363 ILE A O 1 ATOM 2894 C CB . ILE A 1 363 ? 4.343 -3.202 17.630 1.00 16.65 ? 363 ILE A CB 1 ATOM 2895 C CG1 . ILE A 1 363 ? 4.900 -2.270 18.717 1.00 18.26 ? 363 ILE A CG1 1 ATOM 2896 C CG2 . ILE A 1 363 ? 4.122 -2.522 16.273 1.00 18.32 ? 363 ILE A CG2 1 ATOM 2897 C CD1 . ILE A 1 363 ? 6.476 -1.958 18.569 1.00 18.71 ? 363 ILE A CD1 1 ATOM 2898 N N . ILE A 1 364 ? 3.582 -6.173 18.815 1.00 15.80 ? 364 ILE A N 1 ATOM 2899 C CA . ILE A 1 364 ? 4.034 -7.174 19.756 1.00 15.24 ? 364 ILE A CA 1 ATOM 2900 C C . ILE A 1 364 ? 5.517 -6.918 19.951 1.00 16.89 ? 364 ILE A C 1 ATOM 2901 O O . ILE A 1 364 ? 6.195 -6.583 18.976 1.00 15.67 ? 364 ILE A O 1 ATOM 2902 C CB . ILE A 1 364 ? 3.771 -8.622 19.247 1.00 15.39 ? 364 ILE A CB 1 ATOM 2903 C CG1 . ILE A 1 364 ? 3.893 -9.638 20.402 1.00 15.87 ? 364 ILE A CG1 1 ATOM 2904 C CG2 . ILE A 1 364 ? 4.730 -9.041 18.082 1.00 15.85 ? 364 ILE A CG2 1 ATOM 2905 C CD1 . ILE A 1 364 ? 3.234 -10.992 20.088 1.00 16.13 ? 364 ILE A CD1 1 ATOM 2906 N N . VAL A 1 365 ? 5.968 -7.070 21.199 1.00 16.50 ? 365 VAL A N 1 ATOM 2907 C CA . VAL A 1 365 ? 7.367 -7.031 21.581 1.00 18.69 ? 365 VAL A CA 1 ATOM 2908 C C . VAL A 1 365 ? 7.531 -8.257 22.524 1.00 19.45 ? 365 VAL A C 1 ATOM 2909 O O . VAL A 1 365 ? 6.680 -8.532 23.388 1.00 19.91 ? 365 VAL A O 1 ATOM 2910 C CB . VAL A 1 365 ? 7.772 -5.667 22.256 1.00 18.54 ? 365 VAL A CB 1 ATOM 2911 C CG1 . VAL A 1 365 ? 9.303 -5.554 22.411 1.00 20.76 ? 365 VAL A CG1 1 ATOM 2912 C CG2 . VAL A 1 365 ? 7.283 -4.461 21.453 1.00 19.07 ? 365 VAL A CG2 1 ATOM 2913 N N . ASP A 1 366 ? 8.583 -9.036 22.292 1.00 19.30 ? 366 ASP A N 1 ATOM 2914 C CA . ASP A 1 366 ? 8.867 -10.226 23.092 1.00 19.63 ? 366 ASP A CA 1 ATOM 2915 C C . ASP A 1 366 ? 9.991 -9.839 24.041 1.00 19.23 ? 366 ASP A C 1 ATOM 2916 O O . ASP A 1 366 ? 10.718 -8.896 23.750 1.00 18.44 ? 366 ASP A O 1 ATOM 2917 C CB . ASP A 1 366 ? 9.304 -11.391 22.179 1.00 19.61 ? 366 ASP A CB 1 ATOM 2918 C CG . ASP A 1 366 ? 8.178 -11.894 21.292 1.00 23.82 ? 366 ASP A CG 1 ATOM 2919 O OD1 . ASP A 1 366 ? 7.085 -12.208 21.832 1.00 21.52 ? 366 ASP A OD1 1 ATOM 2920 O OD2 . ASP A 1 366 ? 8.398 -11.992 20.059 1.00 23.02 ? 366 ASP A OD2 1 ATOM 2921 N N . PRO A 1 367 ? 10.089 -10.487 25.210 1.00 18.67 ? 367 PRO A N 1 ATOM 2922 C CA . PRO A 1 367 ? 11.209 -10.092 26.039 1.00 19.01 ? 367 PRO A CA 1 ATOM 2923 C C . PRO A 1 367 ? 12.547 -10.600 25.474 1.00 19.14 ? 367 PRO A C 1 ATOM 2924 O O . PRO A 1 367 ? 13.530 -9.883 25.535 1.00 20.12 ? 367 PRO A O 1 ATOM 2925 C CB . PRO A 1 367 ? 10.926 -10.784 27.377 1.00 18.54 ? 367 PRO A CB 1 ATOM 2926 C CG . PRO A 1 367 ? 10.052 -11.926 27.032 1.00 19.56 ? 367 PRO A CG 1 ATOM 2927 C CD . PRO A 1 367 ? 9.217 -11.468 25.884 1.00 19.06 ? 367 PRO A CD 1 ATOM 2928 N N . ALA A 1 368 ? 12.554 -11.789 24.887 1.00 18.89 ? 368 ALA A N 1 ATOM 2929 C CA . ALA A 1 368 ? 13.849 -12.432 24.600 1.00 19.44 ? 368 ALA A CA 1 ATOM 2930 C C . ALA A 1 368 ? 14.514 -11.732 23.435 1.00 18.78 ? 368 ALA A C 1 ATOM 2931 O O . ALA A 1 368 ? 13.846 -11.378 22.467 1.00 19.88 ? 368 ALA A O 1 ATOM 2932 C CB . ALA A 1 368 ? 13.670 -13.889 24.334 1.00 19.31 ? 368 ALA A CB 1 ATOM 2933 N N . ILE A 1 369 ? 15.838 -11.558 23.517 1.00 18.48 ? 369 ILE A N 1 ATOM 2934 C CA . ILE A 1 369 ? 16.579 -10.766 22.556 1.00 17.37 ? 369 ILE A CA 1 ATOM 2935 C C . ILE A 1 369 ? 17.628 -11.676 21.888 1.00 18.18 ? 369 ILE A C 1 ATOM 2936 O O . ILE A 1 369 ? 18.376 -12.348 22.593 1.00 17.28 ? 369 ILE A O 1 ATOM 2937 C CB . ILE A 1 369 ? 17.311 -9.563 23.237 1.00 17.75 ? 369 ILE A CB 1 ATOM 2938 C CG1 . ILE A 1 369 ? 16.323 -8.596 23.917 1.00 17.08 ? 369 ILE A CG1 1 ATOM 2939 C CG2 . ILE A 1 369 ? 18.205 -8.798 22.215 1.00 19.16 ? 369 ILE A CG2 1 ATOM 2940 C CD1 . ILE A 1 369 ? 15.301 -7.988 22.945 1.00 18.05 ? 369 ILE A CD1 1 ATOM 2941 N N . SER A 1 370 ? 17.655 -11.663 20.553 1.00 18.94 ? 370 SER A N 1 ATOM 2942 C CA . SER A 1 370 ? 18.575 -12.483 19.763 1.00 20.66 ? 370 SER A CA 1 ATOM 2943 C C . SER A 1 370 ? 19.985 -12.161 20.209 1.00 20.58 ? 370 SER A C 1 ATOM 2944 O O . SER A 1 370 ? 20.298 -11.006 20.371 1.00 20.40 ? 370 SER A O 1 ATOM 2945 C CB . SER A 1 370 ? 18.454 -12.140 18.279 1.00 20.52 ? 370 SER A CB 1 ATOM 2946 O OG . SER A 1 370 ? 19.348 -12.950 17.517 1.00 21.49 ? 370 SER A OG 1 ATOM 2947 N N . ASN A 1 371 ? 20.821 -13.171 20.431 1.00 21.72 ? 371 ASN A N 1 ATOM 2948 C CA . ASN A 1 371 ? 22.226 -12.870 20.799 1.00 23.19 ? 371 ASN A CA 1 ATOM 2949 C C . ASN A 1 371 ? 23.143 -12.954 19.587 1.00 24.95 ? 371 ASN A C 1 ATOM 2950 O O . ASN A 1 371 ? 24.370 -12.992 19.735 1.00 25.28 ? 371 ASN A O 1 ATOM 2951 C CB . ASN A 1 371 ? 22.736 -13.791 21.929 1.00 22.70 ? 371 ASN A CB 1 ATOM 2952 C CG . ASN A 1 371 ? 22.782 -15.266 21.533 1.00 24.02 ? 371 ASN A CG 1 ATOM 2953 O OD1 . ASN A 1 371 ? 22.294 -15.660 20.491 1.00 24.49 ? 371 ASN A OD1 1 ATOM 2954 N ND2 . ASN A 1 371 ? 23.360 -16.089 22.404 1.00 24.40 ? 371 ASN A ND2 1 ATOM 2955 N N . ASN A 1 372 ? 22.545 -12.974 18.408 1.00 25.30 ? 372 ASN A N 1 ATOM 2956 C CA . ASN A 1 372 ? 23.312 -13.109 17.172 1.00 27.31 ? 372 ASN A CA 1 ATOM 2957 C C . ASN A 1 372 ? 23.690 -11.725 16.673 1.00 27.34 ? 372 ASN A C 1 ATOM 2958 O O . ASN A 1 372 ? 22.905 -11.050 16.022 1.00 26.79 ? 372 ASN A O 1 ATOM 2959 C CB . ASN A 1 372 ? 22.513 -13.879 16.134 1.00 27.81 ? 372 ASN A CB 1 ATOM 2960 C CG . ASN A 1 372 ? 23.380 -14.386 14.976 1.00 30.09 ? 372 ASN A CG 1 ATOM 2961 O OD1 . ASN A 1 372 ? 24.326 -13.727 14.560 1.00 30.92 ? 372 ASN A OD1 1 ATOM 2962 N ND2 . ASN A 1 372 ? 23.030 -15.543 14.442 1.00 32.79 ? 372 ASN A ND2 1 ATOM 2963 N N . SER A 1 373 ? 24.917 -11.316 16.982 1.00 28.69 ? 373 SER A N 1 ATOM 2964 C CA . SER A 1 373 ? 25.418 -10.028 16.580 1.00 29.73 ? 373 SER A CA 1 ATOM 2965 C C . SER A 1 373 ? 26.926 -10.119 16.355 1.00 31.71 ? 373 SER A C 1 ATOM 2966 O O . SER A 1 373 ? 27.622 -10.788 17.101 1.00 32.32 ? 373 SER A O 1 ATOM 2967 C CB . SER A 1 373 ? 25.161 -9.003 17.666 1.00 29.55 ? 373 SER A CB 1 ATOM 2968 O OG . SER A 1 373 ? 25.469 -7.703 17.196 1.00 26.81 ? 373 SER A OG 1 ATOM 2969 N N . SER A 1 374 ? 27.400 -9.437 15.324 1.00 34.37 ? 374 SER A N 1 ATOM 2970 C CA . SER A 1 374 ? 28.836 -9.372 14.993 1.00 36.93 ? 374 SER A CA 1 ATOM 2971 C C . SER A 1 374 ? 29.140 -7.976 14.435 1.00 38.41 ? 374 SER A C 1 ATOM 2972 O O . SER A 1 374 ? 28.216 -7.209 14.177 1.00 38.36 ? 374 SER A O 1 ATOM 2973 C CB . SER A 1 374 ? 29.183 -10.466 13.968 1.00 36.75 ? 374 SER A CB 1 ATOM 2974 O OG . SER A 1 374 ? 28.430 -10.322 12.764 1.00 37.40 ? 374 SER A OG 1 ATOM 2975 N N . SER A 1 375 ? 30.419 -7.627 14.270 1.00 40.01 ? 375 SER A N 1 ATOM 2976 C CA . SER A 1 375 ? 30.782 -6.375 13.578 1.00 41.25 ? 375 SER A CA 1 ATOM 2977 C C . SER A 1 375 ? 30.221 -6.332 12.153 1.00 41.66 ? 375 SER A C 1 ATOM 2978 O O . SER A 1 375 ? 29.803 -5.280 11.664 1.00 42.62 ? 375 SER A O 1 ATOM 2979 C CB . SER A 1 375 ? 32.305 -6.198 13.532 1.00 41.85 ? 375 SER A CB 1 ATOM 2980 O OG . SER A 1 375 ? 32.874 -6.232 14.838 1.00 43.50 ? 375 SER A OG 1 ATOM 2981 N N . SER A 1 376 ? 30.213 -7.484 11.494 1.00 41.81 ? 376 SER A N 1 ATOM 2982 C CA . SER A 1 376 ? 29.660 -7.624 10.154 1.00 41.83 ? 376 SER A CA 1 ATOM 2983 C C . SER A 1 376 ? 28.179 -7.200 10.119 1.00 41.25 ? 376 SER A C 1 ATOM 2984 O O . SER A 1 376 ? 27.799 -6.288 9.381 1.00 41.36 ? 376 SER A O 1 ATOM 2985 C CB . SER A 1 376 ? 29.833 -9.079 9.690 1.00 42.14 ? 376 SER A CB 1 ATOM 2986 O OG . SER A 1 376 ? 29.528 -9.240 8.317 1.00 44.36 ? 376 SER A OG 1 ATOM 2987 N N . LYS A 1 377 ? 27.351 -7.861 10.929 1.00 39.85 ? 377 LYS A N 1 ATOM 2988 C CA . LYS A 1 377 ? 25.931 -7.534 11.016 1.00 38.25 ? 377 LYS A CA 1 ATOM 2989 C C . LYS A 1 377 ? 25.565 -7.262 12.487 1.00 35.85 ? 377 LYS A C 1 ATOM 2990 O O . LYS A 1 377 ? 25.205 -8.197 13.209 1.00 35.40 ? 377 LYS A O 1 ATOM 2991 C CB . LYS A 1 377 ? 25.106 -8.710 10.493 1.00 39.30 ? 377 LYS A CB 1 ATOM 2992 C CG . LYS A 1 377 ? 24.057 -8.326 9.458 1.00 42.42 ? 377 LYS A CG 1 ATOM 2993 C CD . LYS A 1 377 ? 24.622 -8.388 8.036 1.00 45.82 ? 377 LYS A CD 1 ATOM 2994 C CE . LYS A 1 377 ? 23.615 -7.820 7.024 1.00 46.84 ? 377 LYS A CE 1 ATOM 2995 N NZ . LYS A 1 377 ? 24.081 -8.023 5.628 1.00 47.26 ? 377 LYS A NZ 1 ATOM 2996 N N . PRO A 1 378 ? 25.697 -6.004 12.946 1.00 33.74 ? 378 PRO A N 1 ATOM 2997 C CA . PRO A 1 378 ? 25.363 -5.753 14.351 1.00 31.78 ? 378 PRO A CA 1 ATOM 2998 C C . PRO A 1 378 ? 23.862 -5.910 14.602 1.00 29.23 ? 378 PRO A C 1 ATOM 2999 O O . PRO A 1 378 ? 23.060 -5.579 13.725 1.00 30.15 ? 378 PRO A O 1 ATOM 3000 C CB . PRO A 1 378 ? 25.759 -4.293 14.567 1.00 31.88 ? 378 PRO A CB 1 ATOM 3001 C CG . PRO A 1 378 ? 25.841 -3.693 13.214 1.00 33.14 ? 378 PRO A CG 1 ATOM 3002 C CD . PRO A 1 378 ? 26.160 -4.785 12.255 1.00 33.31 ? 378 PRO A CD 1 ATOM 3003 N N . TYR A 1 379 ? 23.498 -6.401 15.783 1.00 26.18 ? 379 TYR A N 1 ATOM 3004 C CA . TYR A 1 379 ? 22.076 -6.352 16.201 1.00 23.46 ? 379 TYR A CA 1 ATOM 3005 C C . TYR A 1 379 ? 21.990 -5.434 17.401 1.00 21.56 ? 379 TYR A C 1 ATOM 3006 O O . TYR A 1 379 ? 22.312 -5.831 18.516 1.00 21.78 ? 379 TYR A O 1 ATOM 3007 C CB . TYR A 1 379 ? 21.503 -7.751 16.499 1.00 21.71 ? 379 TYR A CB 1 ATOM 3008 C CG . TYR A 1 379 ? 20.039 -7.689 16.967 1.00 20.66 ? 379 TYR A CG 1 ATOM 3009 C CD1 . TYR A 1 379 ? 19.065 -7.056 16.199 1.00 18.84 ? 379 TYR A CD1 1 ATOM 3010 C CD2 . TYR A 1 379 ? 19.663 -8.240 18.182 1.00 21.73 ? 379 TYR A CD2 1 ATOM 3011 C CE1 . TYR A 1 379 ? 17.678 -7.003 16.657 1.00 20.04 ? 379 TYR A CE1 1 ATOM 3012 C CE2 . TYR A 1 379 ? 18.330 -8.186 18.639 1.00 18.90 ? 379 TYR A CE2 1 ATOM 3013 C CZ . TYR A 1 379 ? 17.353 -7.577 17.883 1.00 20.82 ? 379 TYR A CZ 1 ATOM 3014 O OH . TYR A 1 379 ? 16.042 -7.570 18.411 1.00 19.72 ? 379 TYR A OH 1 ATOM 3015 N N . GLY A 1 380 ? 21.577 -4.191 17.145 1.00 21.06 ? 380 GLY A N 1 ATOM 3016 C CA . GLY A 1 380 ? 21.572 -3.103 18.122 1.00 20.89 ? 380 GLY A CA 1 ATOM 3017 C C . GLY A 1 380 ? 21.058 -3.374 19.532 1.00 20.53 ? 380 GLY A C 1 ATOM 3018 O O . GLY A 1 380 ? 21.747 -3.084 20.497 1.00 19.06 ? 380 GLY A O 1 ATOM 3019 N N . PRO A 1 381 ? 19.817 -3.913 19.667 1.00 20.37 ? 381 PRO A N 1 ATOM 3020 C CA . PRO A 1 381 ? 19.234 -4.178 21.006 1.00 19.52 ? 381 PRO A CA 1 ATOM 3021 C C . PRO A 1 381 ? 20.091 -5.108 21.879 1.00 19.29 ? 381 PRO A C 1 ATOM 3022 O O . PRO A 1 381 ? 20.202 -4.900 23.081 1.00 19.69 ? 381 PRO A O 1 ATOM 3023 C CB . PRO A 1 381 ? 17.872 -4.830 20.666 1.00 19.27 ? 381 PRO A CB 1 ATOM 3024 C CG . PRO A 1 381 ? 17.512 -4.204 19.349 1.00 18.79 ? 381 PRO A CG 1 ATOM 3025 C CD . PRO A 1 381 ? 18.864 -4.244 18.595 1.00 19.87 ? 381 PRO A CD 1 ATOM 3026 N N . TYR A 1 382 ? 20.704 -6.108 21.264 1.00 20.41 ? 382 TYR A N 1 ATOM 3027 C CA . TYR A 1 382 ? 21.601 -7.020 21.973 1.00 20.71 ? 382 TYR A CA 1 ATOM 3028 C C . TYR A 1 382 ? 22.914 -6.331 22.363 1.00 21.00 ? 382 TYR A C 1 ATOM 3029 O O . TYR A 1 382 ? 23.365 -6.477 23.503 1.00 20.73 ? 382 TYR A O 1 ATOM 3030 C CB . TYR A 1 382 ? 21.867 -8.280 21.143 1.00 21.79 ? 382 TYR A CB 1 ATOM 3031 C CG . TYR A 1 382 ? 22.862 -9.185 21.795 1.00 22.89 ? 382 TYR A CG 1 ATOM 3032 C CD1 . TYR A 1 382 ? 22.526 -9.898 22.937 1.00 21.71 ? 382 TYR A CD1 1 ATOM 3033 C CD2 . TYR A 1 382 ? 24.179 -9.288 21.304 1.00 24.35 ? 382 TYR A CD2 1 ATOM 3034 C CE1 . TYR A 1 382 ? 23.465 -10.730 23.586 1.00 25.61 ? 382 TYR A CE1 1 ATOM 3035 C CE2 . TYR A 1 382 ? 25.123 -10.119 21.945 1.00 25.47 ? 382 TYR A CE2 1 ATOM 3036 C CZ . TYR A 1 382 ? 24.753 -10.840 23.079 1.00 25.03 ? 382 TYR A CZ 1 ATOM 3037 O OH . TYR A 1 382 ? 25.656 -11.669 23.751 1.00 25.66 ? 382 TYR A OH 1 ATOM 3038 N N . ASP A 1 383 ? 23.556 -5.634 21.417 1.00 21.41 ? 383 ASP A N 1 ATOM 3039 C CA . ASP A 1 383 ? 24.795 -4.880 21.758 1.00 22.63 ? 383 ASP A CA 1 ATOM 3040 C C . ASP A 1 383 ? 24.580 -3.887 22.888 1.00 22.68 ? 383 ASP A C 1 ATOM 3041 O O . ASP A 1 383 ? 25.354 -3.867 23.848 1.00 22.32 ? 383 ASP A O 1 ATOM 3042 C CB . ASP A 1 383 ? 25.363 -4.131 20.540 1.00 22.87 ? 383 ASP A CB 1 ATOM 3043 C CG . ASP A 1 383 ? 25.751 -5.050 19.412 1.00 25.55 ? 383 ASP A CG 1 ATOM 3044 O OD1 . ASP A 1 383 ? 25.822 -6.290 19.610 1.00 25.56 ? 383 ASP A OD1 1 ATOM 3045 O OD2 . ASP A 1 383 ? 25.983 -4.509 18.300 1.00 31.20 ? 383 ASP A OD2 1 ATOM 3046 N N . ARG A 1 384 ? 23.522 -3.066 22.770 1.00 21.73 ? 384 ARG A N 1 ATOM 3047 C CA . ARG A 1 384 ? 23.204 -2.079 23.789 1.00 21.98 ? 384 ARG A CA 1 ATOM 3048 C C . ARG A 1 384 ? 22.875 -2.711 25.129 1.00 21.75 ? 384 ARG A C 1 ATOM 3049 O O . ARG A 1 384 ? 23.309 -2.204 26.162 1.00 21.45 ? 384 ARG A O 1 ATOM 3050 C CB . ARG A 1 384 ? 22.090 -1.126 23.322 1.00 22.23 ? 384 ARG A CB 1 ATOM 3051 C CG . ARG A 1 384 ? 22.534 -0.125 22.272 1.00 22.51 ? 384 ARG A CG 1 ATOM 3052 C CD . ARG A 1 384 ? 21.394 0.860 21.880 1.00 23.00 ? 384 ARG A CD 1 ATOM 3053 N NE . ARG A 1 384 ? 20.335 0.216 21.100 1.00 25.03 ? 384 ARG A NE 1 ATOM 3054 C CZ . ARG A 1 384 ? 20.339 0.093 19.775 1.00 25.57 ? 384 ARG A CZ 1 ATOM 3055 N NH1 . ARG A 1 384 ? 21.344 0.587 19.054 1.00 26.39 ? 384 ARG A NH1 1 ATOM 3056 N NH2 . ARG A 1 384 ? 19.339 -0.517 19.164 1.00 24.81 ? 384 ARG A NH2 1 ATOM 3057 N N . GLY A 1 385 ? 22.107 -3.815 25.125 1.00 22.02 ? 385 GLY A N 1 ATOM 3058 C CA . GLY A 1 385 ? 21.809 -4.548 26.367 1.00 21.42 ? 385 GLY A CA 1 ATOM 3059 C C . GLY A 1 385 ? 23.020 -5.203 27.030 1.00 22.71 ? 385 GLY A C 1 ATOM 3060 O O . GLY A 1 385 ? 23.154 -5.199 28.258 1.00 21.02 ? 385 GLY A O 1 ATOM 3061 N N . SER A 1 386 ? 23.904 -5.768 26.210 1.00 22.97 ? 386 SER A N 1 ATOM 3062 C CA . SER A 1 386 ? 25.146 -6.354 26.726 1.00 25.28 ? 386 SER A CA 1 ATOM 3063 C C . SER A 1 386 ? 26.048 -5.266 27.287 1.00 25.39 ? 386 SER A C 1 ATOM 3064 O O . SER A 1 386 ? 26.665 -5.472 28.305 1.00 26.47 ? 386 SER A O 1 ATOM 3065 C CB . SER A 1 386 ? 25.871 -7.105 25.624 1.00 25.00 ? 386 SER A CB 1 ATOM 3066 O OG . SER A 1 386 ? 25.006 -8.070 25.092 1.00 26.16 ? 386 SER A OG 1 ATOM 3067 N N . ASP A 1 387 ? 26.088 -4.107 26.627 1.00 27.42 ? 387 ASP A N 1 ATOM 3068 C CA . ASP A 1 387 ? 26.862 -2.945 27.124 1.00 28.31 ? 387 ASP A CA 1 ATOM 3069 C C . ASP A 1 387 ? 26.437 -2.554 28.546 1.00 28.55 ? 387 ASP A C 1 ATOM 3070 O O . ASP A 1 387 ? 27.274 -2.229 29.411 1.00 27.35 ? 387 ASP A O 1 ATOM 3071 C CB . ASP A 1 387 ? 26.679 -1.738 26.197 1.00 29.12 ? 387 ASP A CB 1 ATOM 3072 C CG . ASP A 1 387 ? 27.493 -1.835 24.914 1.00 32.78 ? 387 ASP A CG 1 ATOM 3073 O OD1 . ASP A 1 387 ? 28.345 -2.758 24.775 1.00 35.90 ? 387 ASP A OD1 1 ATOM 3074 O OD2 . ASP A 1 387 ? 27.263 -0.969 24.036 1.00 34.60 ? 387 ASP A OD2 1 ATOM 3075 N N . MET A 1 388 ? 25.121 -2.597 28.780 1.00 27.70 ? 388 MET A N 1 ATOM 3076 C CA . MET A 1 388 ? 24.532 -2.199 30.042 1.00 28.19 ? 388 MET A CA 1 ATOM 3077 C C . MET A 1 388 ? 24.424 -3.339 31.043 1.00 25.70 ? 388 MET A C 1 ATOM 3078 O O . MET A 1 388 ? 24.093 -3.122 32.205 1.00 25.24 ? 388 MET A O 1 ATOM 3079 C CB . MET A 1 388 ? 23.151 -1.587 29.786 1.00 27.28 ? 388 MET A CB 1 ATOM 3080 C CG . MET A 1 388 ? 23.222 -0.287 28.966 1.00 30.67 ? 388 MET A CG 1 ATOM 3081 S SD . MET A 1 388 ? 21.607 0.471 28.674 1.00 33.46 ? 388 MET A SD 1 ATOM 3082 C CE . MET A 1 388 ? 21.208 0.913 30.359 1.00 30.25 ? 388 MET A CE 1 ATOM 3083 N N . LYS A 1 389 ? 24.687 -4.552 30.575 1.00 24.94 ? 389 LYS A N 1 ATOM 3084 C CA . LYS A 1 389 ? 24.777 -5.724 31.443 1.00 24.78 ? 389 LYS A CA 1 ATOM 3085 C C . LYS A 1 389 ? 23.449 -5.999 32.173 1.00 23.43 ? 389 LYS A C 1 ATOM 3086 O O . LYS A 1 389 ? 23.431 -6.269 33.375 1.00 22.69 ? 389 LYS A O 1 ATOM 3087 C CB . LYS A 1 389 ? 25.955 -5.579 32.437 1.00 24.80 ? 389 LYS A CB 1 ATOM 3088 C CG . LYS A 1 389 ? 27.324 -5.564 31.715 1.00 26.59 ? 389 LYS A CG 1 ATOM 3089 C CD . LYS A 1 389 ? 28.454 -5.184 32.647 1.00 27.85 ? 389 LYS A CD 1 ATOM 3090 C CE . LYS A 1 389 ? 29.764 -5.148 31.848 1.00 32.53 ? 389 LYS A CE 1 ATOM 3091 N NZ . LYS A 1 389 ? 30.127 -6.535 31.357 1.00 35.98 ? 389 LYS A NZ 1 ATOM 3092 N N . ILE A 1 390 ? 22.365 -5.976 31.407 1.00 22.53 ? 390 ILE A N 1 ATOM 3093 C CA . ILE A 1 390 ? 21.014 -6.055 31.978 1.00 21.53 ? 390 ILE A CA 1 ATOM 3094 C C . ILE A 1 390 ? 20.308 -7.386 31.669 1.00 21.24 ? 390 ILE A C 1 ATOM 3095 O O . ILE A 1 390 ? 19.093 -7.467 31.760 1.00 20.51 ? 390 ILE A O 1 ATOM 3096 C CB . ILE A 1 390 ? 20.136 -4.829 31.576 1.00 21.73 ? 390 ILE A CB 1 ATOM 3097 C CG1 . ILE A 1 390 ? 20.140 -4.508 30.076 1.00 21.86 ? 390 ILE A CG1 1 ATOM 3098 C CG2 . ILE A 1 390 ? 20.587 -3.585 32.349 1.00 23.23 ? 390 ILE A CG2 1 ATOM 3099 C CD1 . ILE A 1 390 ? 19.546 -5.551 29.093 1.00 21.81 ? 390 ILE A CD1 1 ATOM 3100 N N . TRP A 1 391 ? 21.078 -8.425 31.315 1.00 20.54 ? 391 TRP A N 1 ATOM 3101 C CA . TRP A 1 391 ? 20.484 -9.776 31.101 1.00 19.90 ? 391 TRP A CA 1 ATOM 3102 C C . TRP A 1 391 ? 20.306 -10.596 32.359 1.00 18.80 ? 391 TRP A C 1 ATOM 3103 O O . TRP A 1 391 ? 20.990 -10.367 33.351 1.00 18.11 ? 391 TRP A O 1 ATOM 3104 C CB . TRP A 1 391 ? 21.293 -10.586 30.096 1.00 19.87 ? 391 TRP A CB 1 ATOM 3105 C CG . TRP A 1 391 ? 21.707 -9.849 28.858 1.00 20.00 ? 391 TRP A CG 1 ATOM 3106 C CD1 . TRP A 1 391 ? 23.004 -9.695 28.385 1.00 21.50 ? 391 TRP A CD1 1 ATOM 3107 C CD2 . TRP A 1 391 ? 20.860 -9.197 27.909 1.00 20.60 ? 391 TRP A CD2 1 ATOM 3108 N NE1 . TRP A 1 391 ? 22.991 -8.992 27.206 1.00 21.41 ? 391 TRP A NE1 1 ATOM 3109 C CE2 . TRP A 1 391 ? 21.690 -8.676 26.895 1.00 19.63 ? 391 TRP A CE2 1 ATOM 3110 C CE3 . TRP A 1 391 ? 19.468 -9.025 27.796 1.00 19.15 ? 391 TRP A CE3 1 ATOM 3111 C CZ2 . TRP A 1 391 ? 21.181 -7.981 25.809 1.00 21.69 ? 391 TRP A CZ2 1 ATOM 3112 C CZ3 . TRP A 1 391 ? 18.973 -8.316 26.728 1.00 21.43 ? 391 TRP A CZ3 1 ATOM 3113 C CH2 . TRP A 1 391 ? 19.817 -7.809 25.738 1.00 20.48 ? 391 TRP A CH2 1 ATOM 3114 N N . VAL A 1 392 ? 19.360 -11.552 32.327 1.00 17.73 ? 392 VAL A N 1 ATOM 3115 C CA . VAL A 1 392 ? 19.259 -12.556 33.362 1.00 16.69 ? 392 VAL A CA 1 ATOM 3116 C C . VAL A 1 392 ? 20.537 -13.415 33.252 1.00 17.57 ? 392 VAL A C 1 ATOM 3117 O O . VAL A 1 392 ? 20.930 -13.780 32.142 1.00 17.85 ? 392 VAL A O 1 ATOM 3118 C CB . VAL A 1 392 ? 18.048 -13.470 33.135 1.00 16.17 ? 392 VAL A CB 1 ATOM 3119 C CG1 . VAL A 1 392 ? 18.034 -14.616 34.149 1.00 17.24 ? 392 VAL A CG1 1 ATOM 3120 C CG2 . VAL A 1 392 ? 16.712 -12.635 33.188 1.00 13.02 ? 392 VAL A CG2 1 ATOM 3121 N N . ASN A 1 393 ? 21.179 -13.692 34.373 1.00 18.49 ? 393 ASN A N 1 ATOM 3122 C CA . ASN A 1 393 ? 22.435 -14.467 34.353 1.00 20.60 ? 393 ASN A CA 1 ATOM 3123 C C . ASN A 1 393 ? 22.163 -15.885 34.751 1.00 21.52 ? 393 ASN A C 1 ATOM 3124 O O . ASN A 1 393 ? 21.203 -16.150 35.454 1.00 19.58 ? 393 ASN A O 1 ATOM 3125 C CB . ASN A 1 393 ? 23.441 -13.865 35.326 1.00 20.33 ? 393 ASN A CB 1 ATOM 3126 C CG . ASN A 1 393 ? 23.934 -12.517 34.866 1.00 20.26 ? 393 ASN A CG 1 ATOM 3127 O OD1 . ASN A 1 393 ? 23.824 -12.180 33.685 1.00 20.96 ? 393 ASN A OD1 1 ATOM 3128 N ND2 . ASN A 1 393 ? 24.474 -11.741 35.798 1.00 20.76 ? 393 ASN A ND2 1 ATOM 3129 N N . SER A 1 394 ? 23.026 -16.794 34.293 1.00 21.94 ? 394 SER A N 1 ATOM 3130 C CA . SER A 1 394 ? 23.093 -18.152 34.820 1.00 24.21 ? 394 SER A CA 1 ATOM 3131 C C . SER A 1 394 ? 23.498 -18.150 36.290 1.00 24.32 ? 394 SER A C 1 ATOM 3132 O O . SER A 1 394 ? 23.789 -17.109 36.869 1.00 24.60 ? 394 SER A O 1 ATOM 3133 C CB . SER A 1 394 ? 24.127 -18.965 34.018 1.00 25.29 ? 394 SER A CB 1 ATOM 3134 O OG . SER A 1 394 ? 23.651 -19.121 32.700 1.00 30.99 ? 394 SER A OG 1 ATOM 3135 N N . SER A 1 395 ? 23.536 -19.330 36.890 1.00 25.15 ? 395 SER A N 1 ATOM 3136 C CA . SER A 1 395 ? 23.756 -19.438 38.312 1.00 27.31 ? 395 SER A CA 1 ATOM 3137 C C . SER A 1 395 ? 25.163 -18.978 38.774 1.00 28.01 ? 395 SER A C 1 ATOM 3138 O O . SER A 1 395 ? 25.325 -18.608 39.932 1.00 28.61 ? 395 SER A O 1 ATOM 3139 C CB . SER A 1 395 ? 23.411 -20.840 38.816 1.00 27.02 ? 395 SER A CB 1 ATOM 3140 O OG . SER A 1 395 ? 24.487 -21.734 38.552 1.00 28.33 ? 395 SER A OG 1 ATOM 3141 N N . ASP A 1 396 ? 26.141 -18.924 37.871 1.00 29.28 ? 396 ASP A N 1 ATOM 3142 C CA . ASP A 1 396 ? 27.456 -18.326 38.217 1.00 29.84 ? 396 ASP A CA 1 ATOM 3143 C C . ASP A 1 396 ? 27.369 -16.832 38.557 1.00 29.74 ? 396 ASP A C 1 ATOM 3144 O O . ASP A 1 396 ? 28.319 -16.223 39.047 1.00 29.71 ? 396 ASP A O 1 ATOM 3145 C CB . ASP A 1 396 ? 28.545 -18.624 37.166 1.00 30.13 ? 396 ASP A CB 1 ATOM 3146 C CG . ASP A 1 396 ? 28.345 -17.897 35.826 1.00 31.81 ? 396 ASP A CG 1 ATOM 3147 O OD1 . ASP A 1 396 ? 27.430 -17.042 35.672 1.00 28.81 ? 396 ASP A OD1 1 ATOM 3148 O OD2 . ASP A 1 396 ? 29.159 -18.174 34.906 1.00 30.45 ? 396 ASP A OD2 1 ATOM 3149 N N . GLY A 1 397 ? 26.208 -16.244 38.283 1.00 29.13 ? 397 GLY A N 1 ATOM 3150 C CA . GLY A 1 397 ? 25.963 -14.855 38.597 1.00 28.25 ? 397 GLY A CA 1 ATOM 3151 C C . GLY A 1 397 ? 26.607 -13.864 37.646 1.00 28.39 ? 397 GLY A C 1 ATOM 3152 O O . GLY A 1 397 ? 26.523 -12.664 37.879 1.00 28.80 ? 397 GLY A O 1 ATOM 3153 N N . VAL A 1 398 ? 27.254 -14.333 36.575 1.00 27.88 ? 398 VAL A N 1 ATOM 3154 C CA . VAL A 1 398 ? 27.959 -13.400 35.667 1.00 27.41 ? 398 VAL A CA 1 ATOM 3155 C C . VAL A 1 398 ? 27.781 -13.620 34.169 1.00 26.13 ? 398 VAL A C 1 ATOM 3156 O O . VAL A 1 398 ? 28.036 -12.729 33.370 1.00 27.14 ? 398 VAL A O 1 ATOM 3157 C CB . VAL A 1 398 ? 29.476 -13.317 35.971 1.00 28.36 ? 398 VAL A CB 1 ATOM 3158 C CG1 . VAL A 1 398 ? 29.691 -12.680 37.331 1.00 29.44 ? 398 VAL A CG1 1 ATOM 3159 C CG2 . VAL A 1 398 ? 30.121 -14.721 35.897 1.00 28.28 ? 398 VAL A CG2 1 ATOM 3160 N N . THR A 1 399 ? 27.356 -14.812 33.796 1.00 24.97 ? 399 THR A N 1 ATOM 3161 C CA . THR A 1 399 ? 27.196 -15.153 32.409 1.00 25.52 ? 399 THR A CA 1 ATOM 3162 C C . THR A 1 399 ? 25.716 -15.066 32.041 1.00 24.62 ? 399 THR A C 1 ATOM 3163 O O . THR A 1 399 ? 24.920 -15.752 32.661 1.00 23.07 ? 399 THR A O 1 ATOM 3164 C CB . THR A 1 399 ? 27.709 -16.589 32.177 1.00 25.95 ? 399 THR A CB 1 ATOM 3165 O OG1 . THR A 1 399 ? 29.068 -16.669 32.657 1.00 27.81 ? 399 THR A OG1 1 ATOM 3166 C CG2 . THR A 1 399 ? 27.665 -16.952 30.713 1.00 27.23 ? 399 THR A CG2 1 ATOM 3167 N N . PRO A 1 400 ? 25.366 -14.229 31.043 1.00 24.54 ? 400 PRO A N 1 ATOM 3168 C CA . PRO A 1 400 ? 23.969 -14.207 30.565 1.00 23.60 ? 400 PRO A CA 1 ATOM 3169 C C . PRO A 1 400 ? 23.444 -15.598 30.208 1.00 23.88 ? 400 PRO A C 1 ATOM 3170 O O . PRO A 1 400 ? 24.095 -16.360 29.471 1.00 22.65 ? 400 PRO A O 1 ATOM 3171 C CB . PRO A 1 400 ? 24.036 -13.319 29.315 1.00 24.28 ? 400 PRO A CB 1 ATOM 3172 C CG . PRO A 1 400 ? 25.166 -12.404 29.562 1.00 24.30 ? 400 PRO A CG 1 ATOM 3173 C CD . PRO A 1 400 ? 26.188 -13.212 30.362 1.00 23.50 ? 400 PRO A CD 1 ATOM 3174 N N . LEU A 1 401 ? 22.261 -15.924 30.722 1.00 21.62 ? 401 LEU A N 1 ATOM 3175 C CA . LEU A 1 401 ? 21.640 -17.198 30.408 1.00 22.04 ? 401 LEU A CA 1 ATOM 3176 C C . LEU A 1 401 ? 21.177 -17.197 28.957 1.00 21.97 ? 401 LEU A C 1 ATOM 3177 O O . LEU A 1 401 ? 20.574 -16.229 28.490 1.00 21.33 ? 401 LEU A O 1 ATOM 3178 C CB . LEU A 1 401 ? 20.479 -17.478 31.385 1.00 20.86 ? 401 LEU A CB 1 ATOM 3179 C CG . LEU A 1 401 ? 19.680 -18.782 31.185 1.00 22.76 ? 401 LEU A CG 1 ATOM 3180 C CD1 . LEU A 1 401 ? 19.100 -19.263 32.477 1.00 22.94 ? 401 LEU A CD1 1 ATOM 3181 C CD2 . LEU A 1 401 ? 18.583 -18.629 30.137 1.00 23.43 ? 401 LEU A CD2 1 ATOM 3182 N N . ILE A 1 402 ? 21.453 -18.285 28.240 1.00 21.94 ? 402 ILE A N 1 ATOM 3183 C CA . ILE A 1 402 ? 21.018 -18.407 26.865 1.00 21.51 ? 402 ILE A CA 1 ATOM 3184 C C . ILE A 1 402 ? 19.901 -19.421 26.730 1.00 20.46 ? 402 ILE A C 1 ATOM 3185 O O . ILE A 1 402 ? 20.005 -20.557 27.189 1.00 20.24 ? 402 ILE A O 1 ATOM 3186 C CB . ILE A 1 402 ? 22.197 -18.779 25.913 1.00 21.68 ? 402 ILE A CB 1 ATOM 3187 C CG1 . ILE A 1 402 ? 23.240 -17.651 25.925 1.00 24.31 ? 402 ILE A CG1 1 ATOM 3188 C CG2 . ILE A 1 402 ? 21.691 -19.029 24.471 1.00 21.99 ? 402 ILE A CG2 1 ATOM 3189 C CD1 . ILE A 1 402 ? 24.586 -18.059 25.356 1.00 26.68 ? 402 ILE A CD1 1 ATOM 3190 N N . GLY A 1 403 ? 18.802 -18.992 26.129 1.00 20.10 ? 403 GLY A N 1 ATOM 3191 C CA . GLY A 1 403 ? 17.719 -19.922 25.837 1.00 18.79 ? 403 GLY A CA 1 ATOM 3192 C C . GLY A 1 403 ? 17.397 -19.793 24.367 1.00 19.24 ? 403 GLY A C 1 ATOM 3193 O O . GLY A 1 403 ? 18.244 -19.404 23.574 1.00 18.98 ? 403 GLY A O 1 ATOM 3194 N N . GLU A 1 404 ? 16.156 -20.104 23.983 1.00 17.94 ? 404 GLU A N 1 ATOM 3195 C CA . GLU A 1 404 ? 15.768 -20.039 22.600 1.00 18.44 ? 404 GLU A CA 1 ATOM 3196 C C . GLU A 1 404 ? 14.321 -19.569 22.505 1.00 18.22 ? 404 GLU A C 1 ATOM 3197 O O . GLU A 1 404 ? 13.458 -20.162 23.153 1.00 18.86 ? 404 GLU A O 1 ATOM 3198 C CB . GLU A 1 404 ? 15.834 -21.456 22.015 1.00 18.98 ? 404 GLU A CB 1 ATOM 3199 C CG . GLU A 1 404 ? 15.734 -21.540 20.510 1.00 23.71 ? 404 GLU A CG 1 ATOM 3200 C CD . GLU A 1 404 ? 15.431 -22.949 20.042 1.00 31.25 ? 404 GLU A CD 1 ATOM 3201 O OE1 . GLU A 1 404 ? 16.051 -23.896 20.594 1.00 34.09 ? 404 GLU A OE1 1 ATOM 3202 O OE2 . GLU A 1 404 ? 14.567 -23.114 19.139 1.00 32.18 ? 404 GLU A OE2 1 ATOM 3203 N N . VAL A 1 405 ? 14.051 -18.553 21.706 1.00 17.33 ? 405 VAL A N 1 ATOM 3204 C CA . VAL A 1 405 ? 12.616 -18.199 21.438 1.00 17.82 ? 405 VAL A CA 1 ATOM 3205 C C . VAL A 1 405 ? 12.489 -17.971 19.941 1.00 17.96 ? 405 VAL A C 1 ATOM 3206 O O . VAL A 1 405 ? 13.165 -18.645 19.173 1.00 18.38 ? 405 VAL A O 1 ATOM 3207 C CB . VAL A 1 405 ? 12.084 -17.050 22.357 1.00 16.99 ? 405 VAL A CB 1 ATOM 3208 C CG1 . VAL A 1 405 ? 10.493 -17.089 22.419 1.00 15.97 ? 405 VAL A CG1 1 ATOM 3209 C CG2 . VAL A 1 405 ? 12.598 -17.253 23.754 1.00 15.94 ? 405 VAL A CG2 1 ATOM 3210 N N . TRP A 1 406 ? 11.654 -17.043 19.506 1.00 18.24 ? 406 TRP A N 1 ATOM 3211 C CA . TRP A 1 406 ? 11.332 -16.892 18.097 1.00 18.63 ? 406 TRP A CA 1 ATOM 3212 C C . TRP A 1 406 ? 12.542 -16.627 17.168 1.00 18.96 ? 406 TRP A C 1 ATOM 3213 O O . TRP A 1 406 ? 12.618 -17.230 16.114 1.00 19.64 ? 406 TRP A O 1 ATOM 3214 C CB . TRP A 1 406 ? 10.342 -15.756 17.924 1.00 18.77 ? 406 TRP A CB 1 ATOM 3215 C CG . TRP A 1 406 ? 9.011 -16.008 18.609 1.00 17.40 ? 406 TRP A CG 1 ATOM 3216 C CD1 . TRP A 1 406 ? 8.418 -15.219 19.559 1.00 20.40 ? 406 TRP A CD1 1 ATOM 3217 C CD2 . TRP A 1 406 ? 8.127 -17.108 18.393 1.00 19.29 ? 406 TRP A CD2 1 ATOM 3218 N NE1 . TRP A 1 406 ? 7.194 -15.756 19.939 1.00 17.68 ? 406 TRP A NE1 1 ATOM 3219 C CE2 . TRP A 1 406 ? 6.983 -16.903 19.227 1.00 17.15 ? 406 TRP A CE2 1 ATOM 3220 C CE3 . TRP A 1 406 ? 8.161 -18.234 17.555 1.00 17.23 ? 406 TRP A CE3 1 ATOM 3221 C CZ2 . TRP A 1 406 ? 5.929 -17.804 19.282 1.00 20.49 ? 406 TRP A CZ2 1 ATOM 3222 C CZ3 . TRP A 1 406 ? 7.076 -19.134 17.592 1.00 19.37 ? 406 TRP A CZ3 1 ATOM 3223 C CH2 . TRP A 1 406 ? 5.978 -18.901 18.455 1.00 19.67 ? 406 TRP A CH2 1 ATOM 3224 N N . PRO A 1 407 ? 13.451 -15.715 17.543 1.00 19.15 ? 407 PRO A N 1 ATOM 3225 C CA . PRO A 1 407 ? 14.554 -15.473 16.595 1.00 20.94 ? 407 PRO A CA 1 ATOM 3226 C C . PRO A 1 407 ? 15.642 -16.566 16.551 1.00 22.92 ? 407 PRO A C 1 ATOM 3227 O O . PRO A 1 407 ? 16.565 -16.480 15.705 1.00 24.09 ? 407 PRO A O 1 ATOM 3228 C CB . PRO A 1 407 ? 15.149 -14.158 17.087 1.00 20.86 ? 407 PRO A CB 1 ATOM 3229 C CG . PRO A 1 407 ? 14.926 -14.163 18.559 1.00 19.16 ? 407 PRO A CG 1 ATOM 3230 C CD . PRO A 1 407 ? 13.552 -14.866 18.741 1.00 19.58 ? 407 PRO A CD 1 ATOM 3231 N N . GLY A 1 408 ? 15.533 -17.577 17.403 1.00 22.26 ? 408 GLY A N 1 ATOM 3232 C CA . GLY A 1 408 ? 16.673 -18.511 17.645 1.00 23.27 ? 408 GLY A CA 1 ATOM 3233 C C . GLY A 1 408 ? 17.225 -18.304 19.045 1.00 22.90 ? 408 GLY A C 1 ATOM 3234 O O . GLY A 1 408 ? 16.462 -17.938 19.954 1.00 22.24 ? 408 GLY A O 1 ATOM 3235 N N . GLN A 1 409 ? 18.539 -18.521 19.249 1.00 21.96 ? 409 GLN A N 1 ATOM 3236 C CA . GLN A 1 409 ? 19.175 -18.316 20.562 1.00 22.57 ? 409 GLN A CA 1 ATOM 3237 C C . GLN A 1 409 ? 18.972 -16.897 21.046 1.00 20.82 ? 409 GLN A C 1 ATOM 3238 O O . GLN A 1 409 ? 19.063 -15.929 20.268 1.00 20.36 ? 409 GLN A O 1 ATOM 3239 C CB . GLN A 1 409 ? 20.707 -18.578 20.543 1.00 22.80 ? 409 GLN A CB 1 ATOM 3240 C CG . GLN A 1 409 ? 21.144 -20.006 20.735 1.00 28.22 ? 409 GLN A CG 1 ATOM 3241 C CD . GLN A 1 409 ? 22.628 -20.133 21.127 1.00 26.87 ? 409 GLN A CD 1 ATOM 3242 O OE1 . GLN A 1 409 ? 23.394 -19.145 21.169 1.00 32.63 ? 409 GLN A OE1 1 ATOM 3243 N NE2 . GLN A 1 409 ? 23.028 -21.346 21.443 1.00 34.76 ? 409 GLN A NE2 1 ATOM 3244 N N . THR A 1 410 ? 18.716 -16.767 22.348 1.00 20.17 ? 410 THR A N 1 ATOM 3245 C CA . THR A 1 410 ? 18.395 -15.471 22.917 1.00 19.76 ? 410 THR A CA 1 ATOM 3246 C C . THR A 1 410 ? 18.895 -15.357 24.331 1.00 17.60 ? 410 THR A C 1 ATOM 3247 O O . THR A 1 410 ? 19.072 -16.336 25.024 1.00 18.97 ? 410 THR A O 1 ATOM 3248 C CB . THR A 1 410 ? 16.862 -15.260 23.036 1.00 18.44 ? 410 THR A CB 1 ATOM 3249 O OG1 . THR A 1 410 ? 16.297 -16.387 23.726 1.00 20.27 ? 410 THR A OG1 1 ATOM 3250 C CG2 . THR A 1 410 ? 16.229 -15.143 21.675 1.00 20.47 ? 410 THR A CG2 1 ATOM 3251 N N . VAL A 1 411 ? 19.080 -14.119 24.747 1.00 17.65 ? 411 VAL A N 1 ATOM 3252 C CA . VAL A 1 411 ? 19.232 -13.751 26.148 1.00 16.97 ? 411 VAL A CA 1 ATOM 3253 C C . VAL A 1 411 ? 17.904 -13.087 26.616 1.00 17.62 ? 411 VAL A C 1 ATOM 3254 O O . VAL A 1 411 ? 17.046 -12.765 25.805 1.00 17.22 ? 411 VAL A O 1 ATOM 3255 C CB . VAL A 1 411 ? 20.440 -12.820 26.345 1.00 17.54 ? 411 VAL A CB 1 ATOM 3256 C CG1 . VAL A 1 411 ? 21.771 -13.651 26.221 1.00 16.19 ? 411 VAL A CG1 1 ATOM 3257 C CG2 . VAL A 1 411 ? 20.395 -11.660 25.365 1.00 16.89 ? 411 VAL A CG2 1 ATOM 3258 N N . PHE A 1 412 ? 17.764 -12.902 27.912 1.00 17.68 ? 412 PHE A N 1 ATOM 3259 C CA . PHE A 1 412 ? 16.489 -12.446 28.505 1.00 18.14 ? 412 PHE A CA 1 ATOM 3260 C C . PHE A 1 412 ? 16.771 -11.219 29.360 1.00 17.46 ? 412 PHE A C 1 ATOM 3261 O O . PHE A 1 412 ? 17.615 -11.260 30.257 1.00 17.95 ? 412 PHE A O 1 ATOM 3262 C CB . PHE A 1 412 ? 15.866 -13.592 29.349 1.00 17.23 ? 412 PHE A CB 1 ATOM 3263 C CG . PHE A 1 412 ? 15.562 -14.831 28.556 1.00 16.76 ? 412 PHE A CG 1 ATOM 3264 C CD1 . PHE A 1 412 ? 14.325 -14.979 27.947 1.00 18.46 ? 412 PHE A CD1 1 ATOM 3265 C CD2 . PHE A 1 412 ? 16.541 -15.832 28.348 1.00 19.15 ? 412 PHE A CD2 1 ATOM 3266 C CE1 . PHE A 1 412 ? 14.035 -16.118 27.201 1.00 18.43 ? 412 PHE A CE1 1 ATOM 3267 C CE2 . PHE A 1 412 ? 16.253 -16.959 27.593 1.00 17.88 ? 412 PHE A CE2 1 ATOM 3268 C CZ . PHE A 1 412 ? 14.982 -17.109 27.029 1.00 18.18 ? 412 PHE A CZ 1 ATOM 3269 N N . PRO A 1 413 ? 16.032 -10.123 29.133 1.00 17.18 ? 413 PRO A N 1 ATOM 3270 C CA . PRO A 1 413 ? 16.254 -8.950 29.963 1.00 16.97 ? 413 PRO A CA 1 ATOM 3271 C C . PRO A 1 413 ? 15.862 -9.186 31.404 1.00 17.56 ? 413 PRO A C 1 ATOM 3272 O O . PRO A 1 413 ? 14.895 -9.923 31.692 1.00 18.76 ? 413 PRO A O 1 ATOM 3273 C CB . PRO A 1 413 ? 15.342 -7.879 29.343 1.00 16.57 ? 413 PRO A CB 1 ATOM 3274 C CG . PRO A 1 413 ? 14.983 -8.401 27.994 1.00 16.48 ? 413 PRO A CG 1 ATOM 3275 C CD . PRO A 1 413 ? 14.981 -9.906 28.126 1.00 16.38 ? 413 PRO A CD 1 ATOM 3276 N N . ASP A 1 414 ? 16.591 -8.555 32.312 1.00 15.73 ? 414 ASP A N 1 ATOM 3277 C CA . ASP A 1 414 ? 16.265 -8.678 33.723 1.00 17.45 ? 414 ASP A CA 1 ATOM 3278 C C . ASP A 1 414 ? 15.530 -7.396 34.070 1.00 17.12 ? 414 ASP A C 1 ATOM 3279 O O . ASP A 1 414 ? 16.126 -6.351 34.380 1.00 18.04 ? 414 ASP A O 1 ATOM 3280 C CB . ASP A 1 414 ? 17.518 -8.898 34.607 1.00 17.19 ? 414 ASP A CB 1 ATOM 3281 C CG . ASP A 1 414 ? 17.262 -8.628 36.089 1.00 19.78 ? 414 ASP A CG 1 ATOM 3282 O OD1 . ASP A 1 414 ? 16.083 -8.631 36.548 1.00 21.18 ? 414 ASP A OD1 1 ATOM 3283 O OD2 . ASP A 1 414 ? 18.238 -8.400 36.826 1.00 20.60 ? 414 ASP A OD2 1 ATOM 3284 N N . TYR A 1 415 ? 14.211 -7.443 33.944 1.00 18.55 ? 415 TYR A N 1 ATOM 3285 C CA . TYR A 1 415 ? 13.435 -6.205 34.131 1.00 17.83 ? 415 TYR A CA 1 ATOM 3286 C C . TYR A 1 415 ? 13.344 -5.774 35.588 1.00 19.36 ? 415 TYR A C 1 ATOM 3287 O O . TYR A 1 415 ? 12.840 -4.667 35.881 1.00 20.71 ? 415 TYR A O 1 ATOM 3288 C CB . TYR A 1 415 ? 12.035 -6.349 33.511 1.00 17.38 ? 415 TYR A CB 1 ATOM 3289 C CG . TYR A 1 415 ? 11.993 -6.551 32.019 1.00 15.61 ? 415 TYR A CG 1 ATOM 3290 C CD1 . TYR A 1 415 ? 12.091 -5.481 31.155 1.00 15.70 ? 415 TYR A CD1 1 ATOM 3291 C CD2 . TYR A 1 415 ? 11.792 -7.811 31.477 1.00 13.70 ? 415 TYR A CD2 1 ATOM 3292 C CE1 . TYR A 1 415 ? 12.032 -5.646 29.774 1.00 14.51 ? 415 TYR A CE1 1 ATOM 3293 C CE2 . TYR A 1 415 ? 11.729 -7.990 30.089 1.00 16.38 ? 415 TYR A CE2 1 ATOM 3294 C CZ . TYR A 1 415 ? 11.887 -6.900 29.257 1.00 16.12 ? 415 TYR A CZ 1 ATOM 3295 O OH . TYR A 1 415 ? 11.802 -7.085 27.902 1.00 17.94 ? 415 TYR A OH 1 ATOM 3296 N N . THR A 1 416 ? 13.831 -6.612 36.507 1.00 18.41 ? 416 THR A N 1 ATOM 3297 C CA . THR A 1 416 ? 13.883 -6.242 37.931 1.00 19.04 ? 416 THR A CA 1 ATOM 3298 C C . THR A 1 416 ? 15.019 -5.267 38.243 1.00 20.60 ? 416 THR A C 1 ATOM 3299 O O . THR A 1 416 ? 15.038 -4.637 39.300 1.00 20.05 ? 416 THR A O 1 ATOM 3300 C CB . THR A 1 416 ? 13.913 -7.468 38.888 1.00 18.85 ? 416 THR A CB 1 ATOM 3301 O OG1 . THR A 1 416 ? 15.212 -8.107 38.879 1.00 18.92 ? 416 THR A OG1 1 ATOM 3302 C CG2 . THR A 1 416 ? 12.842 -8.474 38.508 1.00 18.17 ? 416 THR A CG2 1 ATOM 3303 N N . ASN A 1 417 ? 15.970 -5.174 37.321 1.00 21.20 ? 417 ASN A N 1 ATOM 3304 C CA . ASN A 1 417 ? 17.043 -4.186 37.371 1.00 23.42 ? 417 ASN A CA 1 ATOM 3305 C C . ASN A 1 417 ? 16.549 -2.828 36.829 1.00 24.29 ? 417 ASN A C 1 ATOM 3306 O O . ASN A 1 417 ? 16.142 -2.750 35.672 1.00 24.04 ? 417 ASN A O 1 ATOM 3307 C CB . ASN A 1 417 ? 18.191 -4.731 36.508 1.00 22.11 ? 417 ASN A CB 1 ATOM 3308 C CG . ASN A 1 417 ? 19.436 -3.856 36.539 1.00 25.03 ? 417 ASN A CG 1 ATOM 3309 O OD1 . ASN A 1 417 ? 19.375 -2.711 36.936 1.00 24.45 ? 417 ASN A OD1 1 ATOM 3310 N ND2 . ASN A 1 417 ? 20.568 -4.409 36.116 1.00 24.81 ? 417 ASN A ND2 1 ATOM 3311 N N . PRO A 1 418 ? 16.573 -1.740 37.660 1.00 26.23 ? 418 PRO A N 1 ATOM 3312 C CA . PRO A 1 418 ? 16.152 -0.389 37.201 1.00 26.43 ? 418 PRO A CA 1 ATOM 3313 C C . PRO A 1 418 ? 16.845 0.060 35.906 1.00 26.65 ? 418 PRO A C 1 ATOM 3314 O O . PRO A 1 418 ? 16.231 0.716 35.053 1.00 25.41 ? 418 PRO A O 1 ATOM 3315 C CB . PRO A 1 418 ? 16.587 0.528 38.361 1.00 27.23 ? 418 PRO A CB 1 ATOM 3316 C CG . PRO A 1 418 ? 16.527 -0.342 39.565 1.00 28.21 ? 418 PRO A CG 1 ATOM 3317 C CD . PRO A 1 418 ? 16.972 -1.724 39.079 1.00 26.83 ? 418 PRO A CD 1 ATOM 3318 N N . ASN A 1 419 ? 18.112 -0.331 35.752 1.00 26.24 ? 419 ASN A N 1 ATOM 3319 C CA . ASN A 1 419 ? 18.864 -0.024 34.550 1.00 26.55 ? 419 ASN A CA 1 ATOM 3320 C C . ASN A 1 419 ? 18.307 -0.706 33.304 1.00 24.87 ? 419 ASN A C 1 ATOM 3321 O O . ASN A 1 419 ? 18.517 -0.226 32.188 1.00 23.62 ? 419 ASN A O 1 ATOM 3322 C CB . ASN A 1 419 ? 20.345 -0.405 34.752 1.00 27.73 ? 419 ASN A CB 1 ATOM 3323 C CG . ASN A 1 419 ? 21.140 0.680 35.471 1.00 32.97 ? 419 ASN A CG 1 ATOM 3324 O OD1 . ASN A 1 419 ? 20.719 1.849 35.534 1.00 39.36 ? 419 ASN A OD1 1 ATOM 3325 N ND2 . ASN A 1 419 ? 22.306 0.304 36.014 1.00 37.62 ? 419 ASN A ND2 1 ATOM 3326 N N . CYS A 1 420 ? 17.643 -1.857 33.489 1.00 23.46 ? 420 CYS A N 1 ATOM 3327 C CA . CYS A 1 420 ? 17.026 -2.570 32.379 1.00 22.67 ? 420 CYS A CA 1 ATOM 3328 C C . CYS A 1 420 ? 15.884 -1.760 31.774 1.00 22.57 ? 420 CYS A C 1 ATOM 3329 O O . CYS A 1 420 ? 15.721 -1.718 30.570 1.00 21.45 ? 420 CYS A O 1 ATOM 3330 C CB . CYS A 1 420 ? 16.523 -3.945 32.804 1.00 22.42 ? 420 CYS A CB 1 ATOM 3331 S SG . CYS A 1 420 ? 15.895 -4.958 31.423 1.00 22.71 ? 420 CYS A SG 1 ATOM 3332 N N . ALA A 1 421 ? 15.115 -1.093 32.614 1.00 23.16 ? 421 ALA A N 1 ATOM 3333 C CA . ALA A 1 421 ? 14.076 -0.199 32.118 1.00 23.15 ? 421 ALA A CA 1 ATOM 3334 C C . ALA A 1 421 ? 14.670 0.977 31.337 1.00 23.38 ? 421 ALA A C 1 ATOM 3335 O O . ALA A 1 421 ? 14.053 1.467 30.406 1.00 24.22 ? 421 ALA A O 1 ATOM 3336 C CB . ALA A 1 421 ? 13.260 0.295 33.258 1.00 23.59 ? 421 ALA A CB 1 ATOM 3337 N N . VAL A 1 422 ? 15.861 1.450 31.711 1.00 23.08 ? 422 VAL A N 1 ATOM 3338 C CA . VAL A 1 422 ? 16.501 2.503 30.922 1.00 22.71 ? 422 VAL A CA 1 ATOM 3339 C C . VAL A 1 422 ? 16.827 1.963 29.536 1.00 21.21 ? 422 VAL A C 1 ATOM 3340 O O . VAL A 1 422 ? 16.569 2.626 28.554 1.00 22.36 ? 422 VAL A O 1 ATOM 3341 C CB . VAL A 1 422 ? 17.825 3.031 31.572 1.00 23.50 ? 422 VAL A CB 1 ATOM 3342 C CG1 . VAL A 1 422 ? 18.581 3.912 30.609 1.00 23.10 ? 422 VAL A CG1 1 ATOM 3343 C CG2 . VAL A 1 422 ? 17.538 3.748 32.884 1.00 25.24 ? 422 VAL A CG2 1 ATOM 3344 N N . TRP A 1 423 ? 17.374 0.749 29.466 1.00 20.34 ? 423 TRP A N 1 ATOM 3345 C CA . TRP A 1 423 ? 17.726 0.109 28.195 1.00 19.59 ? 423 TRP A CA 1 ATOM 3346 C C . TRP A 1 423 ? 16.473 -0.101 27.352 1.00 19.10 ? 423 TRP A C 1 ATOM 3347 O O . TRP A 1 423 ? 16.466 0.185 26.176 1.00 17.87 ? 423 TRP A O 1 ATOM 3348 C CB . TRP A 1 423 ? 18.436 -1.231 28.441 1.00 20.05 ? 423 TRP A CB 1 ATOM 3349 C CG . TRP A 1 423 ? 18.419 -2.182 27.247 1.00 20.92 ? 423 TRP A CG 1 ATOM 3350 C CD1 . TRP A 1 423 ? 19.219 -2.138 26.135 1.00 20.31 ? 423 TRP A CD1 1 ATOM 3351 C CD2 . TRP A 1 423 ? 17.546 -3.303 27.071 1.00 19.38 ? 423 TRP A CD2 1 ATOM 3352 N NE1 . TRP A 1 423 ? 18.891 -3.169 25.271 1.00 20.29 ? 423 TRP A NE1 1 ATOM 3353 C CE2 . TRP A 1 423 ? 17.858 -3.889 25.825 1.00 20.15 ? 423 TRP A CE2 1 ATOM 3354 C CE3 . TRP A 1 423 ? 16.515 -3.862 27.850 1.00 17.46 ? 423 TRP A CE3 1 ATOM 3355 C CZ2 . TRP A 1 423 ? 17.190 -5.009 25.337 1.00 18.97 ? 423 TRP A CZ2 1 ATOM 3356 C CZ3 . TRP A 1 423 ? 15.852 -4.979 27.357 1.00 18.60 ? 423 TRP A CZ3 1 ATOM 3357 C CH2 . TRP A 1 423 ? 16.185 -5.530 26.107 1.00 19.59 ? 423 TRP A CH2 1 ATOM 3358 N N . TRP A 1 424 ? 15.422 -0.606 27.994 1.00 17.89 ? 424 TRP A N 1 ATOM 3359 C CA . TRP A 1 424 ? 14.176 -0.944 27.309 1.00 18.00 ? 424 TRP A CA 1 ATOM 3360 C C . TRP A 1 424 ? 13.587 0.334 26.736 1.00 16.49 ? 424 TRP A C 1 ATOM 3361 O O . TRP A 1 424 ? 13.142 0.356 25.602 1.00 17.60 ? 424 TRP A O 1 ATOM 3362 C CB . TRP A 1 424 ? 13.275 -1.575 28.370 1.00 18.18 ? 424 TRP A CB 1 ATOM 3363 C CG . TRP A 1 424 ? 12.009 -2.285 27.955 1.00 19.32 ? 424 TRP A CG 1 ATOM 3364 C CD1 . TRP A 1 424 ? 10.755 -2.069 28.504 1.00 18.67 ? 424 TRP A CD1 1 ATOM 3365 C CD2 . TRP A 1 424 ? 11.862 -3.391 27.050 1.00 19.32 ? 424 TRP A CD2 1 ATOM 3366 N NE1 . TRP A 1 424 ? 9.839 -2.920 27.926 1.00 17.83 ? 424 TRP A NE1 1 ATOM 3367 C CE2 . TRP A 1 424 ? 10.482 -3.744 27.045 1.00 19.16 ? 424 TRP A CE2 1 ATOM 3368 C CE3 . TRP A 1 424 ? 12.738 -4.076 26.186 1.00 18.00 ? 424 TRP A CE3 1 ATOM 3369 C CZ2 . TRP A 1 424 ? 9.977 -4.772 26.245 1.00 19.62 ? 424 TRP A CZ2 1 ATOM 3370 C CZ3 . TRP A 1 424 ? 12.246 -5.090 25.409 1.00 19.80 ? 424 TRP A CZ3 1 ATOM 3371 C CH2 . TRP A 1 424 ? 10.874 -5.440 25.443 1.00 20.01 ? 424 TRP A CH2 1 ATOM 3372 N N . THR A 1 425 ? 13.556 1.383 27.538 1.00 17.67 ? 425 THR A N 1 ATOM 3373 C CA . THR A 1 425 ? 13.001 2.673 27.108 1.00 18.97 ? 425 THR A CA 1 ATOM 3374 C C . THR A 1 425 ? 13.720 3.171 25.836 1.00 19.30 ? 425 THR A C 1 ATOM 3375 O O . THR A 1 425 ? 13.091 3.565 24.866 1.00 18.00 ? 425 THR A O 1 ATOM 3376 C CB . THR A 1 425 ? 13.126 3.720 28.232 1.00 19.33 ? 425 THR A CB 1 ATOM 3377 O OG1 . THR A 1 425 ? 12.399 3.284 29.398 1.00 21.93 ? 425 THR A OG1 1 ATOM 3378 C CG2 . THR A 1 425 ? 12.649 5.089 27.773 1.00 20.01 ? 425 THR A CG2 1 ATOM 3379 N N . LYS A 1 426 ? 15.055 3.117 25.843 1.00 19.42 ? 426 LYS A N 1 ATOM 3380 C CA . LYS A 1 426 ? 15.816 3.562 24.683 1.00 20.39 ? 426 LYS A CA 1 ATOM 3381 C C . LYS A 1 426 ? 15.554 2.727 23.446 1.00 18.71 ? 426 LYS A C 1 ATOM 3382 O O . LYS A 1 426 ? 15.472 3.268 22.347 1.00 20.38 ? 426 LYS A O 1 ATOM 3383 C CB . LYS A 1 426 ? 17.320 3.663 25.005 1.00 20.18 ? 426 LYS A CB 1 ATOM 3384 C CG . LYS A 1 426 ? 18.206 4.009 23.799 1.00 26.59 ? 426 LYS A CG 1 ATOM 3385 C CD . LYS A 1 426 ? 17.904 5.394 23.192 1.00 30.98 ? 426 LYS A CD 1 ATOM 3386 C CE . LYS A 1 426 ? 18.818 6.493 23.751 1.00 33.49 ? 426 LYS A CE 1 ATOM 3387 N NZ . LYS A 1 426 ? 18.368 7.882 23.318 1.00 33.67 ? 426 LYS A NZ 1 ATOM 3388 N N . GLU A 1 427 ? 15.354 1.415 23.603 1.00 19.10 ? 427 GLU A N 1 ATOM 3389 C CA . GLU A 1 427 ? 15.049 0.577 22.448 1.00 18.21 ? 427 GLU A CA 1 ATOM 3390 C C . GLU A 1 427 ? 13.703 0.975 21.821 1.00 18.46 ? 427 GLU A C 1 ATOM 3391 O O . GLU A 1 427 ? 13.555 1.067 20.608 1.00 17.95 ? 427 GLU A O 1 ATOM 3392 C CB . GLU A 1 427 ? 15.067 -0.915 22.796 1.00 17.81 ? 427 GLU A CB 1 ATOM 3393 C CG . GLU A 1 427 ? 16.431 -1.486 23.234 1.00 20.36 ? 427 GLU A CG 1 ATOM 3394 C CD . GLU A 1 427 ? 17.566 -1.303 22.219 1.00 22.25 ? 427 GLU A CD 1 ATOM 3395 O OE1 . GLU A 1 427 ? 17.321 -1.204 20.994 1.00 22.06 ? 427 GLU A OE1 1 ATOM 3396 O OE2 . GLU A 1 427 ? 18.730 -1.259 22.682 1.00 25.42 ? 427 GLU A OE2 1 ATOM 3397 N N . PHE A 1 428 ? 12.717 1.222 22.663 1.00 19.02 ? 428 PHE A N 1 ATOM 3398 C CA . PHE A 1 428 ? 11.438 1.711 22.153 1.00 19.21 ? 428 PHE A CA 1 ATOM 3399 C C . PHE A 1 428 ? 11.503 3.095 21.516 1.00 19.95 ? 428 PHE A C 1 ATOM 3400 O O . PHE A 1 428 ? 10.819 3.334 20.546 1.00 20.34 ? 428 PHE A O 1 ATOM 3401 C CB . PHE A 1 428 ? 10.427 1.742 23.271 1.00 20.08 ? 428 PHE A CB 1 ATOM 3402 C CG . PHE A 1 428 ? 9.803 0.424 23.510 1.00 19.30 ? 428 PHE A CG 1 ATOM 3403 C CD1 . PHE A 1 428 ? 8.832 -0.056 22.647 1.00 21.64 ? 428 PHE A CD1 1 ATOM 3404 C CD2 . PHE A 1 428 ? 10.196 -0.351 24.582 1.00 22.82 ? 428 PHE A CD2 1 ATOM 3405 C CE1 . PHE A 1 428 ? 8.265 -1.298 22.878 1.00 22.16 ? 428 PHE A CE1 1 ATOM 3406 C CE2 . PHE A 1 428 ? 9.618 -1.596 24.806 1.00 22.68 ? 428 PHE A CE2 1 ATOM 3407 C CZ . PHE A 1 428 ? 8.645 -2.041 23.959 1.00 21.83 ? 428 PHE A CZ 1 ATOM 3408 N N . GLU A 1 429 ? 12.311 4.000 22.076 1.00 20.86 ? 429 GLU A N 1 ATOM 3409 C CA . GLU A 1 429 ? 12.450 5.354 21.506 1.00 22.29 ? 429 GLU A CA 1 ATOM 3410 C C . GLU A 1 429 ? 13.024 5.236 20.117 1.00 21.26 ? 429 GLU A C 1 ATOM 3411 O O . GLU A 1 429 ? 12.578 5.879 19.186 1.00 20.93 ? 429 GLU A O 1 ATOM 3412 C CB . GLU A 1 429 ? 13.449 6.175 22.303 1.00 23.79 ? 429 GLU A CB 1 ATOM 3413 C CG . GLU A 1 429 ? 12.976 6.773 23.594 1.00 29.37 ? 429 GLU A CG 1 ATOM 3414 C CD . GLU A 1 429 ? 14.113 7.628 24.179 1.00 36.37 ? 429 GLU A CD 1 ATOM 3415 O OE1 . GLU A 1 429 ? 14.497 8.635 23.530 1.00 40.67 ? 429 GLU A OE1 1 ATOM 3416 O OE2 . GLU A 1 429 ? 14.650 7.268 25.255 1.00 37.85 ? 429 GLU A OE2 1 ATOM 3417 N N . LEU A 1 430 ? 14.092 4.453 19.992 1.00 21.38 ? 430 LEU A N 1 ATOM 3418 C CA . LEU A 1 430 ? 14.710 4.235 18.698 1.00 20.49 ? 430 LEU A CA 1 ATOM 3419 C C . LEU A 1 430 ? 13.761 3.624 17.679 1.00 21.52 ? 430 LEU A C 1 ATOM 3420 O O . LEU A 1 430 ? 13.707 4.066 16.522 1.00 21.21 ? 430 LEU A O 1 ATOM 3421 C CB . LEU A 1 430 ? 15.962 3.368 18.850 1.00 21.94 ? 430 LEU A CB 1 ATOM 3422 C CG . LEU A 1 430 ? 17.103 4.101 19.551 1.00 21.66 ? 430 LEU A CG 1 ATOM 3423 C CD1 . LEU A 1 430 ? 18.205 3.116 19.911 1.00 24.33 ? 430 LEU A CD1 1 ATOM 3424 C CD2 . LEU A 1 430 ? 17.625 5.214 18.635 1.00 26.30 ? 430 LEU A CD2 1 ATOM 3425 N N . PHE A 1 431 ? 13.026 2.588 18.084 1.00 20.34 ? 431 PHE A N 1 ATOM 3426 C CA . PHE A 1 431 ? 12.099 1.952 17.166 1.00 20.48 ? 431 PHE A CA 1 ATOM 3427 C C . PHE A 1 431 ? 10.910 2.851 16.829 1.00 19.98 ? 431 PHE A C 1 ATOM 3428 O O . PHE A 1 431 ? 10.387 2.796 15.710 1.00 19.67 ? 431 PHE A O 1 ATOM 3429 C CB . PHE A 1 431 ? 11.587 0.609 17.705 1.00 20.35 ? 431 PHE A CB 1 ATOM 3430 C CG . PHE A 1 431 ? 10.957 -0.257 16.636 1.00 20.48 ? 431 PHE A CG 1 ATOM 3431 C CD1 . PHE A 1 431 ? 11.628 -0.489 15.422 1.00 20.82 ? 431 PHE A CD1 1 ATOM 3432 C CD2 . PHE A 1 431 ? 9.726 -0.864 16.850 1.00 21.63 ? 431 PHE A CD2 1 ATOM 3433 C CE1 . PHE A 1 431 ? 11.073 -1.283 14.445 1.00 23.14 ? 431 PHE A CE1 1 ATOM 3434 C CE2 . PHE A 1 431 ? 9.154 -1.672 15.869 1.00 21.56 ? 431 PHE A CE2 1 ATOM 3435 C CZ . PHE A 1 431 ? 9.817 -1.877 14.667 1.00 22.58 ? 431 PHE A CZ 1 ATOM 3436 N N . HIS A 1 432 ? 10.466 3.643 17.804 1.00 21.67 ? 432 HIS A N 1 ATOM 3437 C CA . HIS A 1 432 ? 9.309 4.552 17.581 1.00 22.89 ? 432 HIS A CA 1 ATOM 3438 C C . HIS A 1 432 ? 9.668 5.666 16.584 1.00 24.25 ? 432 HIS A C 1 ATOM 3439 O O . HIS A 1 432 ? 8.812 6.192 15.881 1.00 23.53 ? 432 HIS A O 1 ATOM 3440 C CB . HIS A 1 432 ? 8.808 5.152 18.893 1.00 22.60 ? 432 HIS A CB 1 ATOM 3441 C CG . HIS A 1 432 ? 7.478 5.831 18.776 1.00 23.83 ? 432 HIS A CG 1 ATOM 3442 N ND1 . HIS A 1 432 ? 7.346 7.195 18.614 1.00 25.99 ? 432 HIS A ND1 1 ATOM 3443 C CD2 . HIS A 1 432 ? 6.217 5.331 18.784 1.00 23.42 ? 432 HIS A CD2 1 ATOM 3444 C CE1 . HIS A 1 432 ? 6.061 7.509 18.535 1.00 25.47 ? 432 HIS A CE1 1 ATOM 3445 N NE2 . HIS A 1 432 ? 5.355 6.400 18.641 1.00 23.50 ? 432 HIS A NE2 1 ATOM 3446 N N . ASN A 1 433 ? 10.957 5.988 16.506 1.00 25.95 ? 433 ASN A N 1 ATOM 3447 C CA . ASN A 1 433 ? 11.433 6.917 15.489 1.00 27.63 ? 433 ASN A CA 1 ATOM 3448 C C . ASN A 1 433 ? 11.266 6.392 14.064 1.00 27.54 ? 433 ASN A C 1 ATOM 3449 O O . ASN A 1 433 ? 11.203 7.179 13.128 1.00 28.24 ? 433 ASN A O 1 ATOM 3450 C CB . ASN A 1 433 ? 12.894 7.315 15.773 1.00 28.09 ? 433 ASN A CB 1 ATOM 3451 C CG . ASN A 1 433 ? 13.030 8.157 17.018 1.00 30.83 ? 433 ASN A CG 1 ATOM 3452 O OD1 . ASN A 1 433 ? 12.090 8.847 17.419 1.00 36.35 ? 433 ASN A OD1 1 ATOM 3453 N ND2 . ASN A 1 433 ? 14.203 8.113 17.642 1.00 33.38 ? 433 ASN A ND2 1 ATOM 3454 N N . GLN A 1 434 ? 11.193 5.065 13.909 1.00 26.91 ? 434 GLN A N 1 ATOM 3455 C CA . GLN A 1 434 ? 10.972 4.391 12.618 1.00 27.42 ? 434 GLN A CA 1 ATOM 3456 C C . GLN A 1 434 ? 9.497 4.025 12.383 1.00 25.93 ? 434 GLN A C 1 ATOM 3457 O O . GLN A 1 434 ? 8.939 4.267 11.312 1.00 25.09 ? 434 GLN A O 1 ATOM 3458 C CB . GLN A 1 434 ? 11.827 3.115 12.532 1.00 26.80 ? 434 GLN A CB 1 ATOM 3459 C CG . GLN A 1 434 ? 13.337 3.315 12.766 1.00 30.67 ? 434 GLN A CG 1 ATOM 3460 C CD . GLN A 1 434 ? 14.086 2.008 13.021 1.00 30.94 ? 434 GLN A CD 1 ATOM 3461 O OE1 . GLN A 1 434 ? 14.750 1.852 14.056 1.00 37.21 ? 434 GLN A OE1 1 ATOM 3462 N NE2 . GLN A 1 434 ? 13.976 1.059 12.088 1.00 35.99 ? 434 GLN A NE2 1 ATOM 3463 N N . VAL A 1 435 ? 8.864 3.416 13.381 1.00 24.86 ? 435 VAL A N 1 ATOM 3464 C CA . VAL A 1 435 ? 7.483 2.933 13.239 1.00 23.38 ? 435 VAL A CA 1 ATOM 3465 C C . VAL A 1 435 ? 6.697 3.592 14.377 1.00 23.58 ? 435 VAL A C 1 ATOM 3466 O O . VAL A 1 435 ? 6.990 3.343 15.538 1.00 22.21 ? 435 VAL A O 1 ATOM 3467 C CB . VAL A 1 435 ? 7.409 1.379 13.349 1.00 23.36 ? 435 VAL A CB 1 ATOM 3468 C CG1 . VAL A 1 435 ? 5.958 0.843 13.161 1.00 24.07 ? 435 VAL A CG1 1 ATOM 3469 C CG2 . VAL A 1 435 ? 8.375 0.707 12.352 1.00 24.59 ? 435 VAL A CG2 1 ATOM 3470 N N . GLU A 1 436 ? 5.712 4.437 14.057 1.00 22.47 ? 436 GLU A N 1 ATOM 3471 C CA . GLU A 1 436 ? 5.105 5.257 15.106 1.00 22.67 ? 436 GLU A CA 1 ATOM 3472 C C . GLU A 1 436 ? 3.889 4.536 15.690 1.00 22.19 ? 436 GLU A C 1 ATOM 3473 O O . GLU A 1 436 ? 2.754 4.966 15.494 1.00 21.80 ? 436 GLU A O 1 ATOM 3474 C CB . GLU A 1 436 ? 4.702 6.620 14.567 1.00 23.62 ? 436 GLU A CB 1 ATOM 3475 C CG . GLU A 1 436 ? 5.885 7.530 14.287 1.00 29.11 ? 436 GLU A CG 1 ATOM 3476 C CD . GLU A 1 436 ? 5.462 8.976 14.007 1.00 37.41 ? 436 GLU A CD 1 ATOM 3477 O OE1 . GLU A 1 436 ? 4.269 9.222 13.680 1.00 39.11 ? 436 GLU A OE1 1 ATOM 3478 O OE2 . GLU A 1 436 ? 6.341 9.866 14.118 1.00 40.00 ? 436 GLU A OE2 1 ATOM 3479 N N . PHE A 1 437 ? 4.166 3.442 16.379 1.00 20.70 ? 437 PHE A N 1 ATOM 3480 C CA . PHE A 1 437 ? 3.147 2.580 17.017 1.00 19.90 ? 437 PHE A CA 1 ATOM 3481 C C . PHE A 1 437 ? 2.548 3.334 18.212 1.00 19.38 ? 437 PHE A C 1 ATOM 3482 O O . PHE A 1 437 ? 3.170 4.266 18.748 1.00 18.37 ? 437 PHE A O 1 ATOM 3483 C CB . PHE A 1 437 ? 3.784 1.239 17.445 1.00 19.91 ? 437 PHE A CB 1 ATOM 3484 C CG . PHE A 1 437 ? 4.958 1.405 18.376 1.00 17.56 ? 437 PHE A CG 1 ATOM 3485 C CD1 . PHE A 1 437 ? 4.757 1.575 19.738 1.00 16.44 ? 437 PHE A CD1 1 ATOM 3486 C CD2 . PHE A 1 437 ? 6.254 1.460 17.882 1.00 19.20 ? 437 PHE A CD2 1 ATOM 3487 C CE1 . PHE A 1 437 ? 5.799 1.765 20.625 1.00 19.92 ? 437 PHE A CE1 1 ATOM 3488 C CE2 . PHE A 1 437 ? 7.303 1.678 18.763 1.00 13.96 ? 437 PHE A CE2 1 ATOM 3489 C CZ . PHE A 1 437 ? 7.084 1.823 20.125 1.00 18.06 ? 437 PHE A CZ 1 ATOM 3490 N N . ASP A 1 438 ? 1.341 2.917 18.622 1.00 18.38 ? 438 ASP A N 1 ATOM 3491 C CA . ASP A 1 438 ? 0.543 3.623 19.626 1.00 17.63 ? 438 ASP A CA 1 ATOM 3492 C C . ASP A 1 438 ? 0.467 2.885 20.970 1.00 16.98 ? 438 ASP A C 1 ATOM 3493 O O . ASP A 1 438 ? 0.089 3.458 21.991 1.00 16.78 ? 438 ASP A O 1 ATOM 3494 C CB . ASP A 1 438 ? -0.878 3.781 19.089 1.00 17.20 ? 438 ASP A CB 1 ATOM 3495 C CG . ASP A 1 438 ? -0.923 4.635 17.857 1.00 17.01 ? 438 ASP A CG 1 ATOM 3496 O OD1 . ASP A 1 438 ? -0.720 5.857 17.983 1.00 18.78 ? 438 ASP A OD1 1 ATOM 3497 O OD2 . ASP A 1 438 ? -1.103 4.091 16.767 1.00 19.60 ? 438 ASP A OD2 1 ATOM 3498 N N . GLY A 1 439 ? 0.808 1.607 20.960 1.00 16.04 ? 439 GLY A N 1 ATOM 3499 C CA . GLY A 1 439 ? 0.708 0.789 22.171 1.00 15.82 ? 439 GLY A CA 1 ATOM 3500 C C . GLY A 1 439 ? 1.528 -0.471 21.953 1.00 15.68 ? 439 GLY A C 1 ATOM 3501 O O . GLY A 1 439 ? 1.976 -0.719 20.832 1.00 15.78 ? 439 GLY A O 1 ATOM 3502 N N . ILE A 1 440 ? 1.686 -1.254 23.016 1.00 15.79 ? 440 ILE A N 1 ATOM 3503 C CA . ILE A 1 440 ? 2.648 -2.356 23.044 1.00 15.59 ? 440 ILE A CA 1 ATOM 3504 C C . ILE A 1 440 ? 1.967 -3.598 23.586 1.00 16.03 ? 440 ILE A C 1 ATOM 3505 O O . ILE A 1 440 ? 1.260 -3.546 24.588 1.00 15.09 ? 440 ILE A O 1 ATOM 3506 C CB . ILE A 1 440 ? 3.847 -1.977 23.932 1.00 15.89 ? 440 ILE A CB 1 ATOM 3507 C CG1 . ILE A 1 440 ? 4.480 -0.667 23.409 1.00 15.95 ? 440 ILE A CG1 1 ATOM 3508 C CG2 . ILE A 1 440 ? 4.870 -3.134 23.974 1.00 18.90 ? 440 ILE A CG2 1 ATOM 3509 C CD1 . ILE A 1 440 ? 5.397 0.031 24.452 1.00 17.23 ? 440 ILE A CD1 1 ATOM 3510 N N . TRP A 1 441 ? 2.207 -4.722 22.927 1.00 15.38 ? 441 TRP A N 1 ATOM 3511 C CA . TRP A 1 441 ? 1.660 -5.986 23.346 1.00 14.28 ? 441 TRP A CA 1 ATOM 3512 C C . TRP A 1 441 ? 2.858 -6.864 23.762 1.00 15.12 ? 441 TRP A C 1 ATOM 3513 O O . TRP A 1 441 ? 3.653 -7.228 22.922 1.00 14.05 ? 441 TRP A O 1 ATOM 3514 C CB . TRP A 1 441 ? 0.820 -6.526 22.184 1.00 15.12 ? 441 TRP A CB 1 ATOM 3515 C CG . TRP A 1 441 ? 0.542 -7.994 22.152 1.00 14.49 ? 441 TRP A CG 1 ATOM 3516 C CD1 . TRP A 1 441 ? 0.525 -8.857 23.210 1.00 16.49 ? 441 TRP A CD1 1 ATOM 3517 C CD2 . TRP A 1 441 ? 0.222 -8.759 20.997 1.00 17.49 ? 441 TRP A CD2 1 ATOM 3518 N NE1 . TRP A 1 441 ? 0.212 -10.132 22.778 1.00 17.62 ? 441 TRP A NE1 1 ATOM 3519 C CE2 . TRP A 1 441 ? 0.026 -10.096 21.420 1.00 17.24 ? 441 TRP A CE2 1 ATOM 3520 C CE3 . TRP A 1 441 ? 0.056 -8.443 19.629 1.00 15.72 ? 441 TRP A CE3 1 ATOM 3521 C CZ2 . TRP A 1 441 ? -0.331 -11.106 20.536 1.00 18.92 ? 441 TRP A CZ2 1 ATOM 3522 C CZ3 . TRP A 1 441 ? -0.263 -9.452 18.757 1.00 16.78 ? 441 TRP A CZ3 1 ATOM 3523 C CH2 . TRP A 1 441 ? -0.440 -10.773 19.210 1.00 17.15 ? 441 TRP A CH2 1 ATOM 3524 N N . ILE A 1 442 ? 3.004 -7.111 25.067 1.00 14.25 ? 442 ILE A N 1 ATOM 3525 C CA . ILE A 1 442 ? 4.168 -7.881 25.600 1.00 16.55 ? 442 ILE A CA 1 ATOM 3526 C C . ILE A 1 442 ? 3.722 -9.313 25.824 1.00 16.54 ? 442 ILE A C 1 ATOM 3527 O O . ILE A 1 442 ? 2.730 -9.586 26.532 1.00 17.16 ? 442 ILE A O 1 ATOM 3528 C CB . ILE A 1 442 ? 4.811 -7.230 26.852 1.00 15.57 ? 442 ILE A CB 1 ATOM 3529 C CG1 . ILE A 1 442 ? 3.738 -6.958 27.937 1.00 15.92 ? 442 ILE A CG1 1 ATOM 3530 C CG2 . ILE A 1 442 ? 5.459 -5.885 26.484 1.00 15.01 ? 442 ILE A CG2 1 ATOM 3531 C CD1 . ILE A 1 442 ? 4.250 -6.446 29.254 1.00 16.46 ? 442 ILE A CD1 1 ATOM 3532 N N . ASP A 1 443 ? 4.420 -10.226 25.159 1.00 16.19 ? 443 ASP A N 1 ATOM 3533 C CA . ASP A 1 443 ? 4.001 -11.608 25.074 1.00 16.35 ? 443 ASP A CA 1 ATOM 3534 C C . ASP A 1 443 ? 5.176 -12.511 25.478 1.00 17.21 ? 443 ASP A C 1 ATOM 3535 O O . ASP A 1 443 ? 6.276 -12.018 25.672 1.00 16.51 ? 443 ASP A O 1 ATOM 3536 C CB . ASP A 1 443 ? 3.590 -11.863 23.626 1.00 15.96 ? 443 ASP A CB 1 ATOM 3537 C CG . ASP A 1 443 ? 2.993 -13.205 23.403 1.00 17.18 ? 443 ASP A CG 1 ATOM 3538 O OD1 . ASP A 1 443 ? 2.342 -13.737 24.309 1.00 17.97 ? 443 ASP A OD1 1 ATOM 3539 O OD2 . ASP A 1 443 ? 3.196 -13.736 22.292 1.00 19.80 ? 443 ASP A OD2 1 ATOM 3540 N N . MET A 1 444 ? 4.900 -13.803 25.647 1.00 16.92 ? 444 MET A N 1 ATOM 3541 C CA . MET A 1 444 ? 5.944 -14.815 25.913 1.00 17.65 ? 444 MET A CA 1 ATOM 3542 C C . MET A 1 444 ? 6.697 -14.475 27.189 1.00 17.21 ? 444 MET A C 1 ATOM 3543 O O . MET A 1 444 ? 7.882 -14.828 27.348 1.00 17.73 ? 444 MET A O 1 ATOM 3544 C CB . MET A 1 444 ? 6.941 -14.829 24.739 1.00 17.73 ? 444 MET A CB 1 ATOM 3545 C CG . MET A 1 444 ? 6.331 -15.127 23.395 1.00 18.88 ? 444 MET A CG 1 ATOM 3546 S SD . MET A 1 444 ? 5.511 -16.702 23.292 1.00 24.48 ? 444 MET A SD 1 ATOM 3547 C CE . MET A 1 444 ? 6.936 -17.799 23.152 1.00 22.79 ? 444 MET A CE 1 ATOM 3548 N N . ASN A 1 445 ? 6.036 -13.753 28.097 1.00 15.53 ? 445 ASN A N 1 ATOM 3549 C CA . ASN A 1 445 ? 6.728 -13.199 29.254 1.00 13.94 ? 445 ASN A CA 1 ATOM 3550 C C . ASN A 1 445 ? 6.503 -13.913 30.594 1.00 14.15 ? 445 ASN A C 1 ATOM 3551 O O . ASN A 1 445 ? 6.609 -13.316 31.666 1.00 13.22 ? 445 ASN A O 1 ATOM 3552 C CB . ASN A 1 445 ? 6.526 -11.681 29.339 1.00 14.70 ? 445 ASN A CB 1 ATOM 3553 C CG . ASN A 1 445 ? 5.038 -11.290 29.471 1.00 14.96 ? 445 ASN A CG 1 ATOM 3554 O OD1 . ASN A 1 445 ? 4.147 -12.124 29.356 1.00 15.61 ? 445 ASN A OD1 1 ATOM 3555 N ND2 . ASN A 1 445 ? 4.795 -10.034 29.744 1.00 14.87 ? 445 ASN A ND2 1 ATOM 3556 N N . GLU A 1 446 ? 6.261 -15.223 30.512 1.00 14.23 ? 446 GLU A N 1 ATOM 3557 C CA . GLU A 1 446 ? 6.195 -16.076 31.704 1.00 15.46 ? 446 GLU A CA 1 ATOM 3558 C C . GLU A 1 446 ? 7.479 -16.233 32.536 1.00 17.08 ? 446 GLU A C 1 ATOM 3559 O O . GLU A 1 446 ? 7.373 -16.304 33.736 1.00 18.18 ? 446 GLU A O 1 ATOM 3560 C CB . GLU A 1 446 ? 5.627 -17.453 31.368 1.00 14.02 ? 446 GLU A CB 1 ATOM 3561 C CG . GLU A 1 446 ? 4.122 -17.412 30.934 1.00 17.55 ? 446 GLU A CG 1 ATOM 3562 C CD . GLU A 1 446 ? 3.931 -16.805 29.567 1.00 22.94 ? 446 GLU A CD 1 ATOM 3563 O OE1 . GLU A 1 446 ? 4.797 -17.009 28.655 1.00 20.87 ? 446 GLU A OE1 1 ATOM 3564 O OE2 . GLU A 1 446 ? 2.925 -16.071 29.400 1.00 23.17 ? 446 GLU A OE2 1 ATOM 3565 N N . VAL A 1 447 ? 8.690 -16.304 31.981 1.00 19.30 ? 447 VAL A N 1 ATOM 3566 C CA . VAL A 1 447 ? 9.065 -16.166 30.588 1.00 20.78 ? 447 VAL A CA 1 ATOM 3567 C C . VAL A 1 447 ? 9.025 -17.526 29.847 1.00 21.51 ? 447 VAL A C 1 ATOM 3568 O O . VAL A 1 447 ? 9.270 -18.589 30.448 1.00 22.05 ? 447 VAL A O 1 ATOM 3569 C CB . VAL A 1 447 ? 10.448 -15.398 30.533 1.00 22.18 ? 447 VAL A CB 1 ATOM 3570 C CG1 . VAL A 1 447 ? 11.593 -16.274 30.972 1.00 24.80 ? 447 VAL A CG1 1 ATOM 3571 C CG2 . VAL A 1 447 ? 10.715 -14.801 29.166 1.00 23.89 ? 447 VAL A CG2 1 ATOM 3572 N N . SER A 1 448 ? 8.618 -17.496 28.576 1.00 20.12 ? 448 SER A N 1 ATOM 3573 C CA . SER A 1 448 ? 8.547 -18.669 27.716 1.00 20.73 ? 448 SER A CA 1 ATOM 3574 C C . SER A 1 448 ? 9.920 -18.924 27.052 1.00 20.59 ? 448 SER A C 1 ATOM 3575 O O . SER A 1 448 ? 10.563 -18.004 26.509 1.00 20.67 ? 448 SER A O 1 ATOM 3576 C CB . SER A 1 448 ? 7.436 -18.504 26.678 1.00 21.38 ? 448 SER A CB 1 ATOM 3577 O OG . SER A 1 448 ? 7.259 -19.684 25.892 1.00 23.05 ? 448 SER A OG 1 ATOM 3578 N N . ASN A 1 449 ? 10.370 -20.163 27.177 1.00 18.32 ? 449 ASN A N 1 ATOM 3579 C CA . ASN A 1 449 ? 11.636 -20.634 26.608 1.00 18.01 ? 449 ASN A CA 1 ATOM 3580 C C . ASN A 1 449 ? 11.314 -21.909 25.794 1.00 18.41 ? 449 ASN A C 1 ATOM 3581 O O . ASN A 1 449 ? 10.504 -22.762 26.240 1.00 17.75 ? 449 ASN A O 1 ATOM 3582 C CB . ASN A 1 449 ? 12.587 -20.915 27.772 1.00 17.86 ? 449 ASN A CB 1 ATOM 3583 C CG . ASN A 1 449 ? 14.057 -20.982 27.362 1.00 18.68 ? 449 ASN A CG 1 ATOM 3584 O OD1 . ASN A 1 449 ? 14.399 -20.862 26.199 1.00 20.41 ? 449 ASN A OD1 1 ATOM 3585 N ND2 . ASN A 1 449 ? 14.921 -21.185 28.344 1.00 18.75 ? 449 ASN A ND2 1 ATOM 3586 N N . PHE A 1 450 ? 11.878 -22.011 24.582 1.00 17.70 ? 450 PHE A N 1 ATOM 3587 C CA . PHE A 1 450 ? 11.625 -23.144 23.692 1.00 20.06 ? 450 PHE A CA 1 ATOM 3588 C C . PHE A 1 450 ? 12.512 -24.328 24.049 1.00 21.43 ? 450 PHE A C 1 ATOM 3589 O O . PHE A 1 450 ? 12.285 -25.439 23.580 1.00 23.30 ? 450 PHE A O 1 ATOM 3590 C CB . PHE A 1 450 ? 11.793 -22.776 22.201 1.00 19.57 ? 450 PHE A CB 1 ATOM 3591 C CG . PHE A 1 450 ? 10.736 -21.817 21.675 1.00 19.51 ? 450 PHE A CG 1 ATOM 3592 C CD1 . PHE A 1 450 ? 9.587 -21.545 22.417 1.00 21.00 ? 450 PHE A CD1 1 ATOM 3593 C CD2 . PHE A 1 450 ? 10.874 -21.230 20.421 1.00 22.28 ? 450 PHE A CD2 1 ATOM 3594 C CE1 . PHE A 1 450 ? 8.605 -20.685 21.947 1.00 20.00 ? 450 PHE A CE1 1 ATOM 3595 C CE2 . PHE A 1 450 ? 9.886 -20.353 19.939 1.00 22.55 ? 450 PHE A CE2 1 ATOM 3596 C CZ . PHE A 1 450 ? 8.751 -20.092 20.712 1.00 22.74 ? 450 PHE A CZ 1 ATOM 3597 N N . VAL A 1 451 ? 13.517 -24.073 24.878 1.00 21.53 ? 451 VAL A N 1 ATOM 3598 C CA . VAL A 1 451 ? 14.302 -25.122 25.514 1.00 22.05 ? 451 VAL A CA 1 ATOM 3599 C C . VAL A 1 451 ? 13.955 -25.128 27.009 1.00 22.34 ? 451 VAL A C 1 ATOM 3600 O O . VAL A 1 451 ? 13.425 -24.148 27.539 1.00 22.69 ? 451 VAL A O 1 ATOM 3601 C CB . VAL A 1 451 ? 15.833 -24.923 25.276 1.00 21.37 ? 451 VAL A CB 1 ATOM 3602 C CG1 . VAL A 1 451 ? 16.155 -25.062 23.819 1.00 23.13 ? 451 VAL A CG1 1 ATOM 3603 C CG2 . VAL A 1 451 ? 16.305 -23.568 25.772 1.00 21.38 ? 451 VAL A CG2 1 ATOM 3604 N N . ASP A 1 452 ? 14.214 -26.235 27.688 1.00 22.21 ? 452 ASP A N 1 ATOM 3605 C CA . ASP A 1 452 ? 13.887 -26.324 29.106 1.00 22.58 ? 452 ASP A CA 1 ATOM 3606 C C . ASP A 1 452 ? 15.056 -25.787 29.896 1.00 22.25 ? 452 ASP A C 1 ATOM 3607 O O . ASP A 1 452 ? 16.130 -26.411 29.925 1.00 22.75 ? 452 ASP A O 1 ATOM 3608 C CB . ASP A 1 452 ? 13.567 -27.767 29.496 1.00 22.53 ? 452 ASP A CB 1 ATOM 3609 C CG . ASP A 1 452 ? 12.266 -28.272 28.878 1.00 25.92 ? 452 ASP A CG 1 ATOM 3610 O OD1 . ASP A 1 452 ? 11.365 -27.458 28.534 1.00 23.80 ? 452 ASP A OD1 1 ATOM 3611 O OD2 . ASP A 1 452 ? 12.130 -29.507 28.763 1.00 29.25 ? 452 ASP A OD2 1 ATOM 3612 N N . GLY A 1 453 ? 14.893 -24.603 30.478 1.00 20.21 ? 453 GLY A N 1 ATOM 3613 C CA . GLY A 1 453 ? 15.932 -24.031 31.342 1.00 20.10 ? 453 GLY A CA 1 ATOM 3614 C C . GLY A 1 453 ? 16.885 -23.106 30.615 1.00 19.83 ? 453 GLY A C 1 ATOM 3615 O O . GLY A 1 453 ? 16.852 -21.909 30.776 1.00 18.31 ? 453 GLY A O 1 ATOM 3616 N N . SER A 1 454 ? 17.770 -23.693 29.815 1.00 20.66 ? 454 SER A N 1 ATOM 3617 C CA . SER A 1 454 ? 18.709 -22.941 29.013 1.00 20.79 ? 454 SER A CA 1 ATOM 3618 C C . SER A 1 454 ? 19.196 -23.922 27.922 1.00 21.11 ? 454 SER A C 1 ATOM 3619 O O . SER A 1 454 ? 18.846 -25.119 27.938 1.00 19.74 ? 454 SER A O 1 ATOM 3620 C CB . SER A 1 454 ? 19.873 -22.473 29.877 1.00 21.94 ? 454 SER A CB 1 ATOM 3621 O OG . SER A 1 454 ? 20.797 -23.560 30.055 1.00 23.77 ? 454 SER A OG 1 ATOM 3622 N N . VAL A 1 455 ? 19.959 -23.421 26.956 1.00 22.10 ? 455 VAL A N 1 ATOM 3623 C CA . VAL A 1 455 ? 20.418 -24.264 25.872 1.00 23.33 ? 455 VAL A CA 1 ATOM 3624 C C . VAL A 1 455 ? 21.326 -25.411 26.414 1.00 24.53 ? 455 VAL A C 1 ATOM 3625 O O . VAL A 1 455 ? 21.624 -26.383 25.704 1.00 25.33 ? 455 VAL A O 1 ATOM 3626 C CB . VAL A 1 455 ? 21.077 -23.417 24.722 1.00 23.97 ? 455 VAL A CB 1 ATOM 3627 C CG1 . VAL A 1 455 ? 20.066 -22.483 24.088 1.00 23.10 ? 455 VAL A CG1 1 ATOM 3628 C CG2 . VAL A 1 455 ? 22.322 -22.645 25.196 1.00 24.10 ? 455 VAL A CG2 1 ATOM 3629 N N . SER A 1 456 ? 21.739 -25.320 27.672 1.00 24.24 ? 456 SER A N 1 ATOM 3630 C CA . SER A 1 456 ? 22.529 -26.409 28.282 1.00 27.16 ? 456 SER A CA 1 ATOM 3631 C C . SER A 1 456 ? 21.797 -27.123 29.441 1.00 26.99 ? 456 SER A C 1 ATOM 3632 O O . SER A 1 456 ? 22.389 -27.836 30.259 1.00 28.04 ? 456 SER A O 1 ATOM 3633 C CB . SER A 1 456 ? 23.940 -25.901 28.635 1.00 26.50 ? 456 SER A CB 1 ATOM 3634 O OG . SER A 1 456 ? 23.851 -24.750 29.441 1.00 31.77 ? 456 SER A OG 1 ATOM 3635 N N . GLY A 1 457 ? 20.473 -26.973 29.466 1.00 26.10 ? 457 GLY A N 1 ATOM 3636 C CA . GLY A 1 457 ? 19.652 -27.571 30.514 1.00 26.16 ? 457 GLY A CA 1 ATOM 3637 C C . GLY A 1 457 ? 19.816 -26.850 31.836 1.00 26.09 ? 457 GLY A C 1 ATOM 3638 O O . GLY A 1 457 ? 20.137 -25.658 31.864 1.00 25.76 ? 457 GLY A O 1 ATOM 3639 N N . CYS A 1 458 ? 19.585 -27.578 32.928 1.00 26.01 ? 458 CYS A N 1 ATOM 3640 C CA . CYS A 1 458 ? 19.627 -27.051 34.294 1.00 26.09 ? 458 CYS A CA 1 ATOM 3641 C C . CYS A 1 458 ? 20.408 -28.001 35.162 1.00 25.50 ? 458 CYS A C 1 ATOM 3642 O O . CYS A 1 458 ? 20.163 -29.193 35.098 1.00 26.73 ? 458 CYS A O 1 ATOM 3643 C CB . CYS A 1 458 ? 18.224 -27.047 34.901 1.00 26.33 ? 458 CYS A CB 1 ATOM 3644 S SG . CYS A 1 458 ? 17.084 -26.061 34.002 1.00 30.43 ? 458 CYS A SG 1 ATOM 3645 N N . SER A 1 459 ? 21.276 -27.478 36.018 1.00 25.31 ? 459 SER A N 1 ATOM 3646 C CA . SER A 1 459 ? 21.962 -28.332 37.005 1.00 26.30 ? 459 SER A CA 1 ATOM 3647 C C . SER A 1 459 ? 20.985 -28.984 37.980 1.00 25.80 ? 459 SER A C 1 ATOM 3648 O O . SER A 1 459 ? 19.975 -28.380 38.355 1.00 25.13 ? 459 SER A O 1 ATOM 3649 C CB . SER A 1 459 ? 22.965 -27.513 37.815 1.00 26.47 ? 459 SER A CB 1 ATOM 3650 O OG . SER A 1 459 ? 23.848 -26.831 36.945 1.00 29.96 ? 459 SER A OG 1 ATOM 3651 N N . THR A 1 460 ? 21.303 -30.204 38.411 1.00 24.71 ? 460 THR A N 1 ATOM 3652 C CA . THR A 1 460 ? 20.544 -30.881 39.463 1.00 24.40 ? 460 THR A CA 1 ATOM 3653 C C . THR A 1 460 ? 20.905 -30.204 40.784 1.00 23.61 ? 460 THR A C 1 ATOM 3654 O O . THR A 1 460 ? 22.076 -30.175 41.184 1.00 24.29 ? 460 THR A O 1 ATOM 3655 C CB . THR A 1 460 ? 20.822 -32.431 39.470 1.00 24.62 ? 460 THR A CB 1 ATOM 3656 O OG1 . THR A 1 460 ? 20.458 -32.993 38.192 1.00 24.03 ? 460 THR A OG1 1 ATOM 3657 C CG2 . THR A 1 460 ? 20.023 -33.136 40.569 1.00 25.40 ? 460 THR A CG2 1 ATOM 3658 N N . ASN A 1 461 ? 19.907 -29.586 41.439 1.00 21.48 ? 461 ASN A N 1 ATOM 3659 C CA . ASN A 1 461 ? 20.109 -28.950 42.734 1.00 19.23 ? 461 ASN A CA 1 ATOM 3660 C C . ASN A 1 461 ? 18.705 -28.713 43.344 1.00 19.64 ? 461 ASN A C 1 ATOM 3661 O O . ASN A 1 461 ? 17.700 -29.029 42.682 1.00 17.45 ? 461 ASN A O 1 ATOM 3662 C CB . ASN A 1 461 ? 20.931 -27.651 42.612 1.00 19.39 ? 461 ASN A CB 1 ATOM 3663 C CG . ASN A 1 461 ? 20.285 -26.607 41.679 1.00 20.83 ? 461 ASN A CG 1 ATOM 3664 O OD1 . ASN A 1 461 ? 19.076 -26.337 41.771 1.00 19.57 ? 461 ASN A OD1 1 ATOM 3665 N ND2 . ASN A 1 461 ? 21.080 -26.016 40.799 1.00 19.37 ? 461 ASN A ND2 1 ATOM 3666 N N . ASN A 1 462 ? 18.647 -28.192 44.568 1.00 18.10 ? 462 ASN A N 1 ATOM 3667 C CA . ASN A 1 462 ? 17.365 -28.042 45.288 1.00 20.46 ? 462 ASN A CA 1 ATOM 3668 C C . ASN A 1 462 ? 16.407 -26.995 44.663 1.00 19.56 ? 462 ASN A C 1 ATOM 3669 O O . ASN A 1 462 ? 15.205 -26.959 45.015 1.00 20.28 ? 462 ASN A O 1 ATOM 3670 C CB . ASN A 1 462 ? 17.619 -27.717 46.766 1.00 21.01 ? 462 ASN A CB 1 ATOM 3671 C CG . ASN A 1 462 ? 18.296 -26.366 46.971 1.00 27.00 ? 462 ASN A CG 1 ATOM 3672 O OD1 . ASN A 1 462 ? 19.413 -26.122 46.474 1.00 32.56 ? 462 ASN A OD1 1 ATOM 3673 N ND2 . ASN A 1 462 ? 17.638 -25.478 47.733 1.00 31.42 ? 462 ASN A ND2 1 ATOM 3674 N N . LEU A 1 463 ? 16.938 -26.125 43.814 1.00 19.43 ? 463 LEU A N 1 ATOM 3675 C CA . LEU A 1 463 ? 16.131 -25.084 43.111 1.00 19.79 ? 463 LEU A CA 1 ATOM 3676 C C . LEU A 1 463 ? 15.505 -25.674 41.869 1.00 20.04 ? 463 LEU A C 1 ATOM 3677 O O . LEU A 1 463 ? 14.293 -25.577 41.675 1.00 19.07 ? 463 LEU A O 1 ATOM 3678 C CB . LEU A 1 463 ? 16.966 -23.841 42.754 1.00 18.87 ? 463 LEU A CB 1 ATOM 3679 C CG . LEU A 1 463 ? 17.545 -23.075 43.952 1.00 21.04 ? 463 LEU A CG 1 ATOM 3680 C CD1 . LEU A 1 463 ? 17.976 -21.697 43.508 1.00 20.19 ? 463 LEU A CD1 1 ATOM 3681 C CD2 . LEU A 1 463 ? 16.549 -22.926 45.099 1.00 23.45 ? 463 LEU A CD2 1 ATOM 3682 N N . ASN A 1 464 ? 16.316 -26.338 41.040 1.00 18.66 ? 464 ASN A N 1 ATOM 3683 C CA . ASN A 1 464 ? 15.748 -26.958 39.821 1.00 20.20 ? 464 ASN A CA 1 ATOM 3684 C C . ASN A 1 464 ? 14.951 -28.216 40.084 1.00 19.44 ? 464 ASN A C 1 ATOM 3685 O O . ASN A 1 464 ? 14.083 -28.583 39.317 1.00 19.89 ? 464 ASN A O 1 ATOM 3686 C CB . ASN A 1 464 ? 16.841 -27.240 38.794 1.00 19.34 ? 464 ASN A CB 1 ATOM 3687 C CG . ASN A 1 464 ? 17.443 -26.008 38.265 1.00 21.87 ? 464 ASN A CG 1 ATOM 3688 O OD1 . ASN A 1 464 ? 18.677 -25.899 38.160 1.00 25.41 ? 464 ASN A OD1 1 ATOM 3689 N ND2 . ASN A 1 464 ? 16.597 -25.041 37.914 1.00 19.73 ? 464 ASN A ND2 1 ATOM 3690 N N . ASN A 1 465 ? 15.263 -28.852 41.202 1.00 19.93 ? 465 ASN A N 1 ATOM 3691 C CA . ASN A 1 465 ? 14.703 -30.144 41.594 1.00 20.13 ? 465 ASN A CA 1 ATOM 3692 C C . ASN A 1 465 ? 14.367 -30.097 43.075 1.00 19.88 ? 465 ASN A C 1 ATOM 3693 O O . ASN A 1 465 ? 15.045 -30.688 43.914 1.00 18.56 ? 465 ASN A O 1 ATOM 3694 C CB . ASN A 1 465 ? 15.708 -31.274 41.259 1.00 21.86 ? 465 ASN A CB 1 ATOM 3695 C CG . ASN A 1 465 ? 16.020 -31.316 39.784 1.00 21.69 ? 465 ASN A CG 1 ATOM 3696 O OD1 . ASN A 1 465 ? 15.271 -31.904 39.006 1.00 26.09 ? 465 ASN A OD1 1 ATOM 3697 N ND2 . ASN A 1 465 ? 17.076 -30.630 39.380 1.00 22.66 ? 465 ASN A ND2 1 ATOM 3698 N N . PRO A 1 466 ? 13.282 -29.381 43.422 1.00 18.76 ? 466 PRO A N 1 ATOM 3699 C CA . PRO A 1 466 ? 13.020 -29.208 44.850 1.00 18.58 ? 466 PRO A CA 1 ATOM 3700 C C . PRO A 1 466 ? 12.416 -30.452 45.525 1.00 18.08 ? 466 PRO A C 1 ATOM 3701 O O . PRO A 1 466 ? 12.003 -31.382 44.832 1.00 18.60 ? 466 PRO A O 1 ATOM 3702 C CB . PRO A 1 466 ? 12.064 -27.976 44.865 1.00 16.73 ? 466 PRO A CB 1 ATOM 3703 C CG . PRO A 1 466 ? 11.262 -28.173 43.578 1.00 18.86 ? 466 PRO A CG 1 ATOM 3704 C CD . PRO A 1 466 ? 12.299 -28.680 42.569 1.00 18.79 ? 466 PRO A CD 1 ATOM 3705 N N . PRO A 1 467 ? 12.388 -30.488 46.877 1.00 19.11 ? 467 PRO A N 1 ATOM 3706 C CA . PRO A 1 467 ? 11.843 -31.637 47.614 1.00 19.02 ? 467 PRO A CA 1 ATOM 3707 C C . PRO A 1 467 ? 10.363 -31.919 47.300 1.00 19.56 ? 467 PRO A C 1 ATOM 3708 O O . PRO A 1 467 ? 9.950 -33.081 47.207 1.00 19.59 ? 467 PRO A O 1 ATOM 3709 C CB . PRO A 1 467 ? 12.056 -31.259 49.080 1.00 19.26 ? 467 PRO A CB 1 ATOM 3710 C CG . PRO A 1 467 ? 12.395 -29.822 49.092 1.00 19.68 ? 467 PRO A CG 1 ATOM 3711 C CD . PRO A 1 467 ? 12.936 -29.450 47.772 1.00 18.69 ? 467 PRO A CD 1 ATOM 3712 N N . PHE A 1 468 ? 9.575 -30.854 47.128 1.00 19.65 ? 468 PHE A N 1 ATOM 3713 C CA . PHE A 1 468 ? 8.188 -30.986 46.696 1.00 18.76 ? 468 PHE A CA 1 ATOM 3714 C C . PHE A 1 468 ? 7.933 -30.119 45.450 1.00 18.14 ? 468 PHE A C 1 ATOM 3715 O O . PHE A 1 468 ? 8.366 -28.960 45.380 1.00 18.70 ? 468 PHE A O 1 ATOM 3716 C CB . PHE A 1 468 ? 7.242 -30.518 47.807 1.00 18.64 ? 468 PHE A CB 1 ATOM 3717 C CG . PHE A 1 468 ? 5.790 -30.557 47.400 1.00 18.72 ? 468 PHE A CG 1 ATOM 3718 C CD1 . PHE A 1 468 ? 5.107 -31.764 47.379 1.00 20.25 ? 468 PHE A CD1 1 ATOM 3719 C CD2 . PHE A 1 468 ? 5.125 -29.395 46.996 1.00 18.28 ? 468 PHE A CD2 1 ATOM 3720 C CE1 . PHE A 1 468 ? 3.753 -31.824 46.997 1.00 19.69 ? 468 PHE A CE1 1 ATOM 3721 C CE2 . PHE A 1 468 ? 3.780 -29.441 46.591 1.00 16.93 ? 468 PHE A CE2 1 ATOM 3722 C CZ . PHE A 1 468 ? 3.095 -30.647 46.608 1.00 19.33 ? 468 PHE A CZ 1 ATOM 3723 N N . THR A 1 469 ? 7.267 -30.694 44.455 1.00 18.00 ? 469 THR A N 1 ATOM 3724 C CA . THR A 1 469 ? 6.895 -29.963 43.256 1.00 17.71 ? 469 THR A CA 1 ATOM 3725 C C . THR A 1 469 ? 5.367 -29.963 43.187 1.00 17.70 ? 469 THR A C 1 ATOM 3726 O O . THR A 1 469 ? 4.763 -31.028 43.154 1.00 17.09 ? 469 THR A O 1 ATOM 3727 C CB . THR A 1 469 ? 7.503 -30.613 41.977 1.00 19.83 ? 469 THR A CB 1 ATOM 3728 O OG1 . THR A 1 469 ? 8.935 -30.720 42.136 1.00 19.97 ? 469 THR A OG1 1 ATOM 3729 C CG2 . THR A 1 469 ? 7.190 -29.726 40.736 1.00 18.44 ? 469 THR A CG2 1 ATOM 3730 N N . PRO A 1 470 ? 4.742 -28.759 43.184 1.00 17.84 ? 470 PRO A N 1 ATOM 3731 C CA . PRO A 1 470 ? 3.286 -28.670 42.994 1.00 19.15 ? 470 PRO A CA 1 ATOM 3732 C C . PRO A 1 470 ? 2.946 -29.323 41.655 1.00 18.57 ? 470 PRO A C 1 ATOM 3733 O O . PRO A 1 470 ? 3.842 -29.507 40.831 1.00 20.03 ? 470 PRO A O 1 ATOM 3734 C CB . PRO A 1 470 ? 3.014 -27.151 42.948 1.00 18.57 ? 470 PRO A CB 1 ATOM 3735 C CG . PRO A 1 470 ? 4.211 -26.514 43.593 1.00 20.30 ? 470 PRO A CG 1 ATOM 3736 C CD . PRO A 1 470 ? 5.387 -27.435 43.309 1.00 17.91 ? 470 PRO A CD 1 ATOM 3737 N N . ARG A 1 471 ? 1.681 -29.676 41.428 1.00 19.51 ? 471 ARG A N 1 ATOM 3738 C CA . ARG A 1 471 ? 1.300 -30.376 40.195 1.00 19.36 ? 471 ARG A CA 1 ATOM 3739 C C . ARG A 1 471 ? 1.242 -29.477 38.944 1.00 18.77 ? 471 ARG A C 1 ATOM 3740 O O . ARG A 1 471 ? 0.260 -29.466 38.213 1.00 18.05 ? 471 ARG A O 1 ATOM 3741 C CB . ARG A 1 471 ? -0.028 -31.126 40.393 1.00 19.81 ? 471 ARG A CB 1 ATOM 3742 C CG . ARG A 1 471 ? -1.213 -30.229 40.739 1.00 23.12 ? 471 ARG A CG 1 ATOM 3743 C CD . ARG A 1 471 ? -2.481 -31.039 40.766 1.00 28.21 ? 471 ARG A CD 1 ATOM 3744 N NE . ARG A 1 471 ? -2.422 -32.060 41.807 1.00 29.66 ? 471 ARG A NE 1 ATOM 3745 C CZ . ARG A 1 471 ? -3.389 -32.941 42.049 1.00 32.62 ? 471 ARG A CZ 1 ATOM 3746 N NH1 . ARG A 1 471 ? -4.504 -32.935 41.307 1.00 32.20 ? 471 ARG A NH1 1 ATOM 3747 N NH2 . ARG A 1 471 ? -3.234 -33.832 43.031 1.00 32.76 ? 471 ARG A NH2 1 ATOM 3748 N N . ILE A 1 472 ? 2.322 -28.751 38.689 1.00 17.76 ? 472 ILE A N 1 ATOM 3749 C CA . ILE A 1 472 ? 2.449 -27.954 37.492 1.00 17.50 ? 472 ILE A CA 1 ATOM 3750 C C . ILE A 1 472 ? 2.590 -28.814 36.240 1.00 18.21 ? 472 ILE A C 1 ATOM 3751 O O . ILE A 1 472 ? 3.040 -29.979 36.302 1.00 17.13 ? 472 ILE A O 1 ATOM 3752 C CB . ILE A 1 472 ? 3.658 -26.989 37.575 1.00 16.59 ? 472 ILE A CB 1 ATOM 3753 C CG1 . ILE A 1 472 ? 4.967 -27.773 37.719 1.00 19.26 ? 472 ILE A CG1 1 ATOM 3754 C CG2 . ILE A 1 472 ? 3.500 -25.991 38.739 1.00 16.27 ? 472 ILE A CG2 1 ATOM 3755 C CD1 . ILE A 1 472 ? 6.112 -26.923 37.516 1.00 19.81 ? 472 ILE A CD1 1 ATOM 3756 N N . LEU A 1 473 ? 2.168 -28.251 35.111 1.00 18.01 ? 473 LEU A N 1 ATOM 3757 C CA . LEU A 1 473 ? 2.251 -28.956 33.848 1.00 18.28 ? 473 LEU A CA 1 ATOM 3758 C C . LEU A 1 473 ? 3.680 -29.466 33.614 1.00 17.60 ? 473 LEU A C 1 ATOM 3759 O O . LEU A 1 473 ? 4.627 -28.701 33.742 1.00 17.89 ? 473 LEU A O 1 ATOM 3760 C CB . LEU A 1 473 ? 1.812 -28.026 32.732 1.00 18.19 ? 473 LEU A CB 1 ATOM 3761 C CG . LEU A 1 473 ? 1.815 -28.634 31.328 1.00 19.72 ? 473 LEU A CG 1 ATOM 3762 C CD1 . LEU A 1 473 ? 0.999 -29.899 31.180 1.00 21.62 ? 473 LEU A CD1 1 ATOM 3763 C CD2 . LEU A 1 473 ? 1.355 -27.581 30.346 1.00 18.49 ? 473 LEU A CD2 1 ATOM 3764 N N . ASP A 1 474 ? 3.802 -30.764 33.331 1.00 18.29 ? 474 ASP A N 1 ATOM 3765 C CA . ASP A 1 474 ? 5.085 -31.464 33.065 1.00 20.51 ? 474 ASP A CA 1 ATOM 3766 C C . ASP A 1 474 ? 5.917 -31.819 34.277 1.00 20.28 ? 474 ASP A C 1 ATOM 3767 O O . ASP A 1 474 ? 6.928 -32.562 34.147 1.00 21.50 ? 474 ASP A O 1 ATOM 3768 C CB . ASP A 1 474 ? 5.957 -30.721 32.037 1.00 20.41 ? 474 ASP A CB 1 ATOM 3769 C CG . ASP A 1 474 ? 5.273 -30.583 30.692 1.00 25.37 ? 474 ASP A CG 1 ATOM 3770 O OD1 . ASP A 1 474 ? 4.650 -31.571 30.226 1.00 28.11 ? 474 ASP A OD1 1 ATOM 3771 O OD2 . ASP A 1 474 ? 5.343 -29.483 30.100 1.00 28.06 ? 474 ASP A OD2 1 ATOM 3772 N N . GLY A 1 475 ? 5.534 -31.295 35.437 1.00 19.55 ? 475 GLY A N 1 ATOM 3773 C CA . GLY A 1 475 ? 6.158 -31.687 36.702 1.00 19.39 ? 475 GLY A CA 1 ATOM 3774 C C . GLY A 1 475 ? 7.576 -31.223 36.993 1.00 18.98 ? 475 GLY A C 1 ATOM 3775 O O . GLY A 1 475 ? 8.186 -31.694 37.948 1.00 19.02 ? 475 GLY A O 1 ATOM 3776 N N . TYR A 1 476 ? 8.108 -30.306 36.194 1.00 17.79 ? 476 TYR A N 1 ATOM 3777 C CA . TYR A 1 476 ? 9.396 -29.699 36.496 1.00 18.29 ? 476 TYR A CA 1 ATOM 3778 C C . TYR A 1 476 ? 9.255 -28.215 36.360 1.00 18.00 ? 476 TYR A C 1 ATOM 3779 O O . TYR A 1 476 ? 8.654 -27.741 35.395 1.00 17.29 ? 476 TYR A O 1 ATOM 3780 C CB . TYR A 1 476 ? 10.487 -30.164 35.519 1.00 20.39 ? 476 TYR A CB 1 ATOM 3781 C CG . TYR A 1 476 ? 10.800 -31.641 35.643 1.00 21.10 ? 476 TYR A CG 1 ATOM 3782 C CD1 . TYR A 1 476 ? 11.948 -32.073 36.309 1.00 22.77 ? 476 TYR A CD1 1 ATOM 3783 C CD2 . TYR A 1 476 ? 9.942 -32.602 35.099 1.00 23.38 ? 476 TYR A CD2 1 ATOM 3784 C CE1 . TYR A 1 476 ? 12.228 -33.425 36.436 1.00 23.89 ? 476 TYR A CE1 1 ATOM 3785 C CE2 . TYR A 1 476 ? 10.221 -33.973 35.223 1.00 24.61 ? 476 TYR A CE2 1 ATOM 3786 C CZ . TYR A 1 476 ? 11.357 -34.361 35.882 1.00 24.36 ? 476 TYR A CZ 1 ATOM 3787 O OH . TYR A 1 476 ? 11.632 -35.706 36.001 1.00 25.21 ? 476 TYR A OH 1 ATOM 3788 N N . LEU A 1 477 ? 9.798 -27.480 37.322 1.00 18.48 ? 477 LEU A N 1 ATOM 3789 C CA . LEU A 1 477 ? 9.691 -25.992 37.331 1.00 18.05 ? 477 LEU A CA 1 ATOM 3790 C C . LEU A 1 477 ? 10.290 -25.344 36.093 1.00 18.53 ? 477 LEU A C 1 ATOM 3791 O O . LEU A 1 477 ? 9.749 -24.375 35.553 1.00 17.08 ? 477 LEU A O 1 ATOM 3792 C CB . LEU A 1 477 ? 10.366 -25.424 38.575 1.00 17.60 ? 477 LEU A CB 1 ATOM 3793 C CG . LEU A 1 477 ? 9.776 -25.804 39.926 1.00 19.36 ? 477 LEU A CG 1 ATOM 3794 C CD1 . LEU A 1 477 ? 10.650 -25.191 41.009 1.00 18.19 ? 477 LEU A CD1 1 ATOM 3795 C CD2 . LEU A 1 477 ? 8.320 -25.275 40.045 1.00 17.15 ? 477 LEU A CD2 1 ATOM 3796 N N . PHE A 1 478 ? 11.407 -25.897 35.605 1.00 18.07 ? 478 PHE A N 1 ATOM 3797 C CA . PHE A 1 478 ? 12.100 -25.234 34.511 1.00 17.36 ? 478 PHE A CA 1 ATOM 3798 C C . PHE A 1 478 ? 11.566 -25.582 33.144 1.00 17.83 ? 478 PHE A C 1 ATOM 3799 O O . PHE A 1 478 ? 12.087 -25.107 32.168 1.00 18.03 ? 478 PHE A O 1 ATOM 3800 C CB . PHE A 1 478 ? 13.575 -25.563 34.589 1.00 18.63 ? 478 PHE A CB 1 ATOM 3801 C CG . PHE A 1 478 ? 13.822 -27.020 34.685 1.00 17.43 ? 478 PHE A CG 1 ATOM 3802 C CD1 . PHE A 1 478 ? 13.728 -27.820 33.553 1.00 21.20 ? 478 PHE A CD1 1 ATOM 3803 C CD2 . PHE A 1 478 ? 14.095 -27.615 35.918 1.00 20.06 ? 478 PHE A CD2 1 ATOM 3804 C CE1 . PHE A 1 478 ? 13.926 -29.200 33.636 1.00 18.19 ? 478 PHE A CE1 1 ATOM 3805 C CE2 . PHE A 1 478 ? 14.306 -28.998 36.004 1.00 18.65 ? 478 PHE A CE2 1 ATOM 3806 C CZ . PHE A 1 478 ? 14.228 -29.774 34.858 1.00 19.56 ? 478 PHE A CZ 1 ATOM 3807 N N . CYS A 1 479 ? 10.542 -26.427 33.049 1.00 19.60 ? 479 CYS A N 1 ATOM 3808 C CA A CYS A 1 479 ? 9.942 -26.775 31.765 0.50 19.72 ? 479 CYS A CA 1 ATOM 3809 C CA B CYS A 1 479 ? 9.955 -26.760 31.740 0.50 19.27 ? 479 CYS A CA 1 ATOM 3810 C C . CYS A 1 479 ? 9.451 -25.534 31.007 1.00 19.28 ? 479 CYS A C 1 ATOM 3811 O O . CYS A 1 479 ? 8.686 -24.745 31.556 1.00 19.00 ? 479 CYS A O 1 ATOM 3812 C CB A CYS A 1 479 ? 8.779 -27.745 31.999 0.50 20.01 ? 479 CYS A CB 1 ATOM 3813 C CB B CYS A 1 479 ? 8.814 -27.769 31.875 0.50 19.42 ? 479 CYS A CB 1 ATOM 3814 S SG A CYS A 1 479 ? 8.088 -28.373 30.515 0.50 23.96 ? 479 CYS A SG 1 ATOM 3815 S SG B CYS A 1 479 ? 9.427 -29.386 32.221 0.50 20.91 ? 479 CYS A SG 1 ATOM 3816 N N . LYS A 1 480 ? 9.903 -25.382 29.757 1.00 19.21 ? 480 LYS A N 1 ATOM 3817 C CA . LYS A 1 480 ? 9.546 -24.239 28.901 1.00 19.38 ? 480 LYS A CA 1 ATOM 3818 C C . LYS A 1 480 ? 9.760 -22.869 29.547 1.00 18.87 ? 480 LYS A C 1 ATOM 3819 O O . LYS A 1 480 ? 9.031 -21.905 29.263 1.00 17.11 ? 480 LYS A O 1 ATOM 3820 C CB . LYS A 1 480 ? 8.099 -24.390 28.366 1.00 20.80 ? 480 LYS A CB 1 ATOM 3821 C CG . LYS A 1 480 ? 7.860 -25.658 27.529 1.00 23.95 ? 480 LYS A CG 1 ATOM 3822 C CD . LYS A 1 480 ? 8.919 -25.899 26.441 1.00 28.52 ? 480 LYS A CD 1 ATOM 3823 C CE . LYS A 1 480 ? 8.772 -27.309 25.846 1.00 29.66 ? 480 LYS A CE 1 ATOM 3824 N NZ . LYS A 1 480 ? 10.103 -27.882 25.430 1.00 35.91 ? 480 LYS A NZ 1 ATOM 3825 N N . THR A 1 481 ? 10.753 -22.779 30.428 1.00 16.71 ? 481 THR A N 1 ATOM 3826 C CA . THR A 1 481 ? 11.086 -21.490 31.038 1.00 16.67 ? 481 THR A CA 1 ATOM 3827 C C . THR A 1 481 ? 12.573 -21.456 31.367 1.00 17.45 ? 481 THR A C 1 ATOM 3828 O O . THR A 1 481 ? 13.333 -22.237 30.783 1.00 17.50 ? 481 THR A O 1 ATOM 3829 C CB . THR A 1 481 ? 10.134 -21.054 32.235 1.00 16.04 ? 481 THR A CB 1 ATOM 3830 O OG1 . THR A 1 481 ? 10.397 -19.692 32.551 1.00 16.51 ? 481 THR A OG1 1 ATOM 3831 C CG2 . THR A 1 481 ? 10.334 -21.897 33.465 1.00 14.41 ? 481 THR A CG2 1 ATOM 3832 N N . LEU A 1 482 ? 12.990 -20.537 32.243 1.00 18.33 ? 482 LEU A N 1 ATOM 3833 C CA . LEU A 1 482 ? 14.394 -20.404 32.653 1.00 18.61 ? 482 LEU A CA 1 ATOM 3834 C C . LEU A 1 482 ? 14.782 -21.338 33.811 1.00 19.36 ? 482 LEU A C 1 ATOM 3835 O O . LEU A 1 482 ? 13.926 -21.757 34.593 1.00 18.66 ? 482 LEU A O 1 ATOM 3836 C CB . LEU A 1 482 ? 14.707 -18.949 33.029 1.00 18.11 ? 482 LEU A CB 1 ATOM 3837 C CG . LEU A 1 482 ? 14.321 -17.849 32.058 1.00 21.00 ? 482 LEU A CG 1 ATOM 3838 C CD1 . LEU A 1 482 ? 14.849 -16.468 32.496 1.00 19.46 ? 482 LEU A CD1 1 ATOM 3839 C CD2 . LEU A 1 482 ? 14.827 -18.193 30.652 1.00 20.32 ? 482 LEU A CD2 1 ATOM 3840 N N . CYS A 1 483 ? 16.080 -21.687 33.902 1.00 18.86 ? 483 CYS A N 1 ATOM 3841 C CA . CYS A 1 483 ? 16.607 -22.385 35.063 1.00 19.31 ? 483 CYS A CA 1 ATOM 3842 C C . CYS A 1 483 ? 16.182 -21.679 36.352 1.00 18.86 ? 483 CYS A C 1 ATOM 3843 O O . CYS A 1 483 ? 16.188 -20.442 36.422 1.00 18.46 ? 483 CYS A O 1 ATOM 3844 C CB . CYS A 1 483 ? 18.142 -22.360 35.029 1.00 20.98 ? 483 CYS A CB 1 ATOM 3845 S SG . CYS A 1 483 ? 18.787 -23.262 33.612 1.00 28.76 ? 483 CYS A SG 1 ATOM 3846 N N . MET A 1 484 ? 15.823 -22.462 37.369 1.00 17.91 ? 484 MET A N 1 ATOM 3847 C CA . MET A 1 484 ? 15.388 -21.863 38.658 1.00 17.75 ? 484 MET A CA 1 ATOM 3848 C C . MET A 1 484 ? 16.546 -21.250 39.436 1.00 17.56 ? 484 MET A C 1 ATOM 3849 O O . MET A 1 484 ? 16.327 -20.472 40.369 1.00 16.74 ? 484 MET A O 1 ATOM 3850 C CB . MET A 1 484 ? 14.693 -22.876 39.552 1.00 16.94 ? 484 MET A CB 1 ATOM 3851 C CG . MET A 1 484 ? 13.343 -23.383 39.030 1.00 15.76 ? 484 MET A CG 1 ATOM 3852 S SD . MET A 1 484 ? 12.140 -21.970 38.938 1.00 18.40 ? 484 MET A SD 1 ATOM 3853 C CE . MET A 1 484 ? 11.966 -21.824 37.193 1.00 14.06 ? 484 MET A CE 1 ATOM 3854 N N . ASP A 1 485 ? 17.783 -21.622 39.091 1.00 18.49 ? 485 ASP A N 1 ATOM 3855 C CA . ASP A 1 485 ? 18.905 -20.977 39.748 1.00 18.67 ? 485 ASP A CA 1 ATOM 3856 C C . ASP A 1 485 ? 19.488 -19.806 38.949 1.00 19.60 ? 485 ASP A C 1 ATOM 3857 O O . ASP A 1 485 ? 20.555 -19.276 39.320 1.00 18.79 ? 485 ASP A O 1 ATOM 3858 C CB . ASP A 1 485 ? 20.004 -21.997 40.123 1.00 19.76 ? 485 ASP A CB 1 ATOM 3859 C CG . ASP A 1 485 ? 20.445 -22.888 38.954 1.00 20.05 ? 485 ASP A CG 1 ATOM 3860 O OD1 . ASP A 1 485 ? 20.045 -22.682 37.782 1.00 20.10 ? 485 ASP A OD1 1 ATOM 3861 O OD2 . ASP A 1 485 ? 21.212 -23.853 39.220 1.00 25.29 ? 485 ASP A OD2 1 ATOM 3862 N N . ALA A 1 486 ? 18.805 -19.387 37.883 1.00 18.56 ? 486 ALA A N 1 ATOM 3863 C CA . ALA A 1 486 ? 19.180 -18.168 37.174 1.00 19.22 ? 486 ALA A CA 1 ATOM 3864 C C . ALA A 1 486 ? 19.020 -16.990 38.136 1.00 20.25 ? 486 ALA A C 1 ATOM 3865 O O . ALA A 1 486 ? 18.269 -17.071 39.136 1.00 20.08 ? 486 ALA A O 1 ATOM 3866 C CB . ALA A 1 486 ? 18.349 -17.977 35.867 1.00 20.08 ? 486 ALA A CB 1 ATOM 3867 N N . VAL A 1 487 ? 19.743 -15.914 37.860 1.00 19.64 ? 487 VAL A N 1 ATOM 3868 C CA . VAL A 1 487 ? 19.975 -14.846 38.830 1.00 21.13 ? 487 VAL A CA 1 ATOM 3869 C C . VAL A 1 487 ? 19.550 -13.509 38.237 1.00 20.08 ? 487 VAL A C 1 ATOM 3870 O O . VAL A 1 487 ? 19.945 -13.165 37.124 1.00 18.82 ? 487 VAL A O 1 ATOM 3871 C CB . VAL A 1 487 ? 21.509 -14.847 39.219 1.00 22.21 ? 487 VAL A CB 1 ATOM 3872 C CG1 . VAL A 1 487 ? 21.994 -13.508 39.685 1.00 25.02 ? 487 VAL A CG1 1 ATOM 3873 C CG2 . VAL A 1 487 ? 21.752 -15.906 40.273 1.00 24.45 ? 487 VAL A CG2 1 ATOM 3874 N N . GLN A 1 488 ? 18.678 -12.805 38.962 1.00 19.95 ? 488 GLN A N 1 ATOM 3875 C CA . GLN A 1 488 ? 18.212 -11.469 38.599 1.00 20.01 ? 488 GLN A CA 1 ATOM 3876 C C . GLN A 1 488 ? 18.410 -10.477 39.768 1.00 20.50 ? 488 GLN A C 1 ATOM 3877 O O . GLN A 1 488 ? 18.798 -10.861 40.879 1.00 21.04 ? 488 GLN A O 1 ATOM 3878 C CB . GLN A 1 488 ? 16.722 -11.531 38.229 1.00 20.25 ? 488 GLN A CB 1 ATOM 3879 C CG . GLN A 1 488 ? 16.490 -12.130 36.871 1.00 20.15 ? 488 GLN A CG 1 ATOM 3880 C CD . GLN A 1 488 ? 15.018 -12.188 36.511 1.00 22.77 ? 488 GLN A CD 1 ATOM 3881 O OE1 . GLN A 1 488 ? 14.444 -11.203 36.051 1.00 27.13 ? 488 GLN A OE1 1 ATOM 3882 N NE2 . GLN A 1 488 ? 14.410 -13.326 36.720 1.00 23.54 ? 488 GLN A NE2 1 ATOM 3883 N N . HIS A 1 489 ? 18.156 -9.196 39.517 1.00 21.14 ? 489 HIS A N 1 ATOM 3884 C CA . HIS A 1 489 ? 18.311 -8.180 40.566 1.00 21.21 ? 489 HIS A CA 1 ATOM 3885 C C . HIS A 1 489 ? 17.492 -8.495 41.836 1.00 21.18 ? 489 HIS A C 1 ATOM 3886 O O . HIS A 1 489 ? 18.023 -8.454 42.950 1.00 21.10 ? 489 HIS A O 1 ATOM 3887 C CB . HIS A 1 489 ? 18.015 -6.778 40.015 1.00 22.21 ? 489 HIS A CB 1 ATOM 3888 C CG . HIS A 1 489 ? 18.278 -5.694 40.997 1.00 23.82 ? 489 HIS A CG 1 ATOM 3889 N ND1 . HIS A 1 489 ? 17.303 -4.819 41.423 1.00 27.23 ? 489 HIS A ND1 1 ATOM 3890 C CD2 . HIS A 1 489 ? 19.407 -5.357 41.663 1.00 27.46 ? 489 HIS A CD2 1 ATOM 3891 C CE1 . HIS A 1 489 ? 17.818 -3.984 42.310 1.00 26.51 ? 489 HIS A CE1 1 ATOM 3892 N NE2 . HIS A 1 489 ? 19.090 -4.295 42.480 1.00 31.65 ? 489 HIS A NE2 1 ATOM 3893 N N . TRP A 1 490 ? 16.227 -8.894 41.671 1.00 20.62 ? 490 TRP A N 1 ATOM 3894 C CA . TRP A 1 490 ? 15.395 -9.223 42.823 1.00 21.20 ? 490 TRP A CA 1 ATOM 3895 C C . TRP A 1 490 ? 15.690 -10.546 43.490 1.00 21.58 ? 490 TRP A C 1 ATOM 3896 O O . TRP A 1 490 ? 15.184 -10.798 44.571 1.00 22.34 ? 490 TRP A O 1 ATOM 3897 C CB . TRP A 1 490 ? 13.903 -9.188 42.461 1.00 20.00 ? 490 TRP A CB 1 ATOM 3898 C CG . TRP A 1 490 ? 13.375 -7.853 42.242 1.00 19.77 ? 490 TRP A CG 1 ATOM 3899 C CD1 . TRP A 1 490 ? 13.994 -6.636 42.503 1.00 20.09 ? 490 TRP A CD1 1 ATOM 3900 C CD2 . TRP A 1 490 ? 12.076 -7.544 41.746 1.00 18.79 ? 490 TRP A CD2 1 ATOM 3901 N NE1 . TRP A 1 490 ? 13.161 -5.611 42.145 1.00 20.68 ? 490 TRP A NE1 1 ATOM 3902 C CE2 . TRP A 1 490 ? 11.980 -6.138 41.670 1.00 21.55 ? 490 TRP A CE2 1 ATOM 3903 C CE3 . TRP A 1 490 ? 10.998 -8.331 41.300 1.00 22.04 ? 490 TRP A CE3 1 ATOM 3904 C CZ2 . TRP A 1 490 ? 10.827 -5.493 41.205 1.00 20.55 ? 490 TRP A CZ2 1 ATOM 3905 C CZ3 . TRP A 1 490 ? 9.849 -7.691 40.843 1.00 21.00 ? 490 TRP A CZ3 1 ATOM 3906 C CH2 . TRP A 1 490 ? 9.776 -6.292 40.797 1.00 20.13 ? 490 TRP A CH2 1 ATOM 3907 N N . GLY A 1 491 ? 16.451 -11.417 42.827 1.00 21.51 ? 491 GLY A N 1 ATOM 3908 C CA . GLY A 1 491 ? 16.828 -12.708 43.393 1.00 21.86 ? 491 GLY A CA 1 ATOM 3909 C C . GLY A 1 491 ? 16.850 -13.825 42.363 1.00 20.87 ? 491 GLY A C 1 ATOM 3910 O O . GLY A 1 491 ? 16.896 -13.571 41.164 1.00 22.07 ? 491 GLY A O 1 ATOM 3911 N N . LYS A 1 492 ? 16.803 -15.067 42.830 1.00 21.33 ? 492 LYS A N 1 ATOM 3912 C CA . LYS A 1 492 ? 16.888 -16.214 41.947 1.00 20.48 ? 492 LYS A CA 1 ATOM 3913 C C . LYS A 1 492 ? 15.548 -16.464 41.271 1.00 20.59 ? 492 LYS A C 1 ATOM 3914 O O . LYS A 1 492 ? 14.489 -16.142 41.819 1.00 18.48 ? 492 LYS A O 1 ATOM 3915 C CB . LYS A 1 492 ? 17.412 -17.438 42.699 1.00 22.15 ? 492 LYS A CB 1 ATOM 3916 C CG . LYS A 1 492 ? 18.932 -17.273 42.974 1.00 24.68 ? 492 LYS A CG 1 ATOM 3917 C CD . LYS A 1 492 ? 19.680 -18.545 43.276 1.00 30.24 ? 492 LYS A CD 1 ATOM 3918 C CE . LYS A 1 492 ? 21.217 -18.301 43.248 1.00 29.86 ? 492 LYS A CE 1 ATOM 3919 N NZ . LYS A 1 492 ? 21.858 -19.126 42.143 1.00 31.93 ? 492 LYS A NZ 1 ATOM 3920 N N . GLN A 1 493 ? 15.607 -17.011 40.069 1.00 19.25 ? 493 GLN A N 1 ATOM 3921 C CA . GLN A 1 493 ? 14.383 -17.353 39.339 1.00 20.08 ? 493 GLN A CA 1 ATOM 3922 C C . GLN A 1 493 ? 13.381 -18.204 40.169 1.00 19.37 ? 493 GLN A C 1 ATOM 3923 O O . GLN A 1 493 ? 12.170 -18.040 40.027 1.00 19.33 ? 493 GLN A O 1 ATOM 3924 C CB . GLN A 1 493 ? 14.782 -17.991 37.996 1.00 20.65 ? 493 GLN A CB 1 ATOM 3925 C CG . GLN A 1 493 ? 13.633 -18.490 37.129 1.00 23.37 ? 493 GLN A CG 1 ATOM 3926 C CD . GLN A 1 493 ? 12.924 -17.383 36.338 1.00 23.60 ? 493 GLN A CD 1 ATOM 3927 O OE1 . GLN A 1 493 ? 13.267 -16.207 36.397 1.00 26.99 ? 493 GLN A OE1 1 ATOM 3928 N NE2 . GLN A 1 493 ? 11.967 -17.789 35.565 1.00 24.28 ? 493 GLN A NE2 1 ATOM 3929 N N . TYR A 1 494 ? 13.877 -19.098 41.029 1.00 17.61 ? 494 TYR A N 1 ATOM 3930 C CA . TYR A 1 494 ? 13.019 -19.895 41.920 1.00 17.72 ? 494 TYR A CA 1 ATOM 3931 C C . TYR A 1 494 ? 11.996 -19.013 42.651 1.00 18.65 ? 494 TYR A C 1 ATOM 3932 O O . TYR A 1 494 ? 10.843 -19.413 42.837 1.00 17.61 ? 494 TYR A O 1 ATOM 3933 C CB . TYR A 1 494 ? 13.890 -20.615 42.940 1.00 16.54 ? 494 TYR A CB 1 ATOM 3934 C CG . TYR A 1 494 ? 13.208 -21.590 43.827 1.00 15.73 ? 494 TYR A CG 1 ATOM 3935 C CD1 . TYR A 1 494 ? 13.006 -22.911 43.411 1.00 14.13 ? 494 TYR A CD1 1 ATOM 3936 C CD2 . TYR A 1 494 ? 12.758 -21.214 45.089 1.00 16.92 ? 494 TYR A CD2 1 ATOM 3937 C CE1 . TYR A 1 494 ? 12.404 -23.841 44.246 1.00 13.81 ? 494 TYR A CE1 1 ATOM 3938 C CE2 . TYR A 1 494 ? 12.146 -22.127 45.915 1.00 15.94 ? 494 TYR A CE2 1 ATOM 3939 C CZ . TYR A 1 494 ? 11.963 -23.437 45.482 1.00 15.31 ? 494 TYR A CZ 1 ATOM 3940 O OH . TYR A 1 494 ? 11.386 -24.354 46.311 1.00 14.83 ? 494 TYR A OH 1 ATOM 3941 N N . ASP A 1 495 ? 12.446 -17.846 43.100 1.00 17.29 ? 495 ASP A N 1 ATOM 3942 C CA . ASP A 1 495 ? 11.596 -16.943 43.880 1.00 19.41 ? 495 ASP A CA 1 ATOM 3943 C C . ASP A 1 495 ? 10.843 -15.919 43.034 1.00 18.78 ? 495 ASP A C 1 ATOM 3944 O O . ASP A 1 495 ? 9.753 -15.474 43.417 1.00 20.45 ? 495 ASP A O 1 ATOM 3945 C CB . ASP A 1 495 ? 12.431 -16.180 44.917 1.00 18.85 ? 495 ASP A CB 1 ATOM 3946 C CG . ASP A 1 495 ? 12.991 -17.068 46.005 1.00 22.38 ? 495 ASP A CG 1 ATOM 3947 O OD1 . ASP A 1 495 ? 12.296 -17.988 46.490 1.00 23.15 ? 495 ASP A OD1 1 ATOM 3948 O OD2 . ASP A 1 495 ? 14.150 -16.795 46.412 1.00 19.88 ? 495 ASP A OD2 1 ATOM 3949 N N . ILE A 1 496 ? 11.423 -15.510 41.903 1.00 17.92 ? 496 ILE A N 1 ATOM 3950 C CA . ILE A 1 496 ? 10.847 -14.364 41.182 1.00 19.16 ? 496 ILE A CA 1 ATOM 3951 C C . ILE A 1 496 ? 10.262 -14.708 39.829 1.00 15.66 ? 496 ILE A C 1 ATOM 3952 O O . ILE A 1 496 ? 9.819 -13.818 39.123 1.00 17.38 ? 496 ILE A O 1 ATOM 3953 C CB . ILE A 1 496 ? 11.825 -13.158 41.067 1.00 19.51 ? 496 ILE A CB 1 ATOM 3954 C CG1 . ILE A 1 496 ? 12.940 -13.463 40.087 1.00 21.29 ? 496 ILE A CG1 1 ATOM 3955 C CG2 . ILE A 1 496 ? 12.341 -12.707 42.468 1.00 20.48 ? 496 ILE A CG2 1 ATOM 3956 C CD1 . ILE A 1 496 ? 13.964 -12.315 39.997 1.00 22.41 ? 496 ILE A CD1 1 ATOM 3957 N N . HIS A 1 497 ? 10.235 -15.999 39.483 1.00 15.63 ? 497 HIS A N 1 ATOM 3958 C CA . HIS A 1 497 ? 9.730 -16.468 38.180 1.00 14.30 ? 497 HIS A CA 1 ATOM 3959 C C . HIS A 1 497 ? 8.321 -15.892 37.924 1.00 13.88 ? 497 HIS A C 1 ATOM 3960 O O . HIS A 1 497 ? 8.016 -15.424 36.826 1.00 13.76 ? 497 HIS A O 1 ATOM 3961 C CB . HIS A 1 497 ? 9.622 -17.998 38.188 1.00 14.08 ? 497 HIS A CB 1 ATOM 3962 C CG . HIS A 1 497 ? 8.983 -18.566 36.961 1.00 15.16 ? 497 HIS A CG 1 ATOM 3963 N ND1 . HIS A 1 497 ? 7.628 -18.830 36.880 1.00 16.96 ? 497 HIS A ND1 1 ATOM 3964 C CD2 . HIS A 1 497 ? 9.508 -18.920 35.766 1.00 14.37 ? 497 HIS A CD2 1 ATOM 3965 C CE1 . HIS A 1 497 ? 7.349 -19.318 35.691 1.00 13.89 ? 497 HIS A CE1 1 ATOM 3966 N NE2 . HIS A 1 497 ? 8.467 -19.374 34.990 1.00 21.83 ? 497 HIS A NE2 1 ATOM 3967 N N . ASN A 1 498 ? 7.478 -15.974 38.940 1.00 15.27 ? 498 ASN A N 1 ATOM 3968 C CA . ASN A 1 498 ? 6.069 -15.531 38.793 1.00 15.18 ? 498 ASN A CA 1 ATOM 3969 C C . ASN A 1 498 ? 5.978 -14.008 38.666 1.00 15.96 ? 498 ASN A C 1 ATOM 3970 O O . ASN A 1 498 ? 4.890 -13.452 38.458 1.00 16.50 ? 498 ASN A O 1 ATOM 3971 C CB . ASN A 1 498 ? 5.251 -16.002 39.994 1.00 14.91 ? 498 ASN A CB 1 ATOM 3972 C CG . ASN A 1 498 ? 4.731 -17.430 39.851 1.00 16.73 ? 498 ASN A CG 1 ATOM 3973 O OD1 . ASN A 1 498 ? 4.078 -17.989 40.753 1.00 21.10 ? 498 ASN A OD1 1 ATOM 3974 N ND2 . ASN A 1 498 ? 4.987 -18.011 38.739 1.00 13.87 ? 498 ASN A ND2 1 ATOM 3975 N N . LEU A 1 499 ? 7.113 -13.333 38.860 1.00 15.47 ? 499 LEU A N 1 ATOM 3976 C CA . LEU A 1 499 ? 7.200 -11.890 38.756 1.00 15.75 ? 499 LEU A CA 1 ATOM 3977 C C . LEU A 1 499 ? 7.759 -11.358 37.475 1.00 15.52 ? 499 LEU A C 1 ATOM 3978 O O . LEU A 1 499 ? 7.920 -10.151 37.327 1.00 15.49 ? 499 LEU A O 1 ATOM 3979 C CB . LEU A 1 499 ? 8.021 -11.307 39.913 1.00 15.64 ? 499 LEU A CB 1 ATOM 3980 C CG . LEU A 1 499 ? 7.578 -11.683 41.334 1.00 16.34 ? 499 LEU A CG 1 ATOM 3981 C CD1 . LEU A 1 499 ? 8.484 -11.070 42.404 1.00 14.00 ? 499 LEU A CD1 1 ATOM 3982 C CD2 . LEU A 1 499 ? 6.105 -11.264 41.587 1.00 17.08 ? 499 LEU A CD2 1 ATOM 3983 N N . TYR A 1 500 ? 8.128 -12.234 36.558 1.00 15.64 ? 500 TYR A N 1 ATOM 3984 C CA . TYR A 1 500 ? 8.762 -11.756 35.329 1.00 15.39 ? 500 TYR A CA 1 ATOM 3985 C C . TYR A 1 500 ? 7.888 -10.837 34.476 1.00 15.41 ? 500 TYR A C 1 ATOM 3986 O O . TYR A 1 500 ? 8.299 -9.732 34.082 1.00 14.89 ? 500 TYR A O 1 ATOM 3987 C CB . TYR A 1 500 ? 9.266 -12.914 34.487 1.00 15.06 ? 500 TYR A CB 1 ATOM 3988 C CG . TYR A 1 500 ? 10.218 -12.443 33.430 1.00 16.67 ? 500 TYR A CG 1 ATOM 3989 C CD1 . TYR A 1 500 ? 11.581 -12.452 33.654 1.00 16.49 ? 500 TYR A CD1 1 ATOM 3990 C CD2 . TYR A 1 500 ? 9.748 -11.981 32.205 1.00 15.71 ? 500 TYR A CD2 1 ATOM 3991 C CE1 . TYR A 1 500 ? 12.463 -12.019 32.667 1.00 16.30 ? 500 TYR A CE1 1 ATOM 3992 C CE2 . TYR A 1 500 ? 10.599 -11.525 31.234 1.00 15.45 ? 500 TYR A CE2 1 ATOM 3993 C CZ . TYR A 1 500 ? 11.972 -11.561 31.483 1.00 17.73 ? 500 TYR A CZ 1 ATOM 3994 O OH . TYR A 1 500 ? 12.812 -11.131 30.518 1.00 18.68 ? 500 TYR A OH 1 ATOM 3995 N N . GLY A 1 501 ? 6.669 -11.287 34.197 1.00 15.87 ? 501 GLY A N 1 ATOM 3996 C CA . GLY A 1 501 ? 5.789 -10.507 33.369 1.00 15.83 ? 501 GLY A CA 1 ATOM 3997 C C . GLY A 1 501 ? 5.297 -9.268 34.086 1.00 15.14 ? 501 GLY A C 1 ATOM 3998 O O . GLY A 1 501 ? 5.077 -8.256 33.456 1.00 16.13 ? 501 GLY A O 1 ATOM 3999 N N . TYR A 1 502 ? 5.133 -9.358 35.397 1.00 15.36 ? 502 TYR A N 1 ATOM 4000 C CA . TYR A 1 502 ? 4.835 -8.180 36.230 1.00 15.36 ? 502 TYR A CA 1 ATOM 4001 C C . TYR A 1 502 ? 5.957 -7.146 36.084 1.00 15.04 ? 502 TYR A C 1 ATOM 4002 O O . TYR A 1 502 ? 5.722 -5.977 35.821 1.00 14.51 ? 502 TYR A O 1 ATOM 4003 C CB . TYR A 1 502 ? 4.698 -8.651 37.672 1.00 16.26 ? 502 TYR A CB 1 ATOM 4004 C CG . TYR A 1 502 ? 4.550 -7.568 38.719 1.00 18.56 ? 502 TYR A CG 1 ATOM 4005 C CD1 . TYR A 1 502 ? 3.346 -6.901 38.884 1.00 16.22 ? 502 TYR A CD1 1 ATOM 4006 C CD2 . TYR A 1 502 ? 5.617 -7.244 39.579 1.00 16.91 ? 502 TYR A CD2 1 ATOM 4007 C CE1 . TYR A 1 502 ? 3.208 -5.919 39.856 1.00 18.02 ? 502 TYR A CE1 1 ATOM 4008 C CE2 . TYR A 1 502 ? 5.477 -6.276 40.589 1.00 17.13 ? 502 TYR A CE2 1 ATOM 4009 C CZ . TYR A 1 502 ? 4.266 -5.612 40.698 1.00 19.77 ? 502 TYR A CZ 1 ATOM 4010 O OH . TYR A 1 502 ? 4.104 -4.668 41.669 1.00 20.11 ? 502 TYR A OH 1 ATOM 4011 N N . SER A 1 503 ? 7.203 -7.577 36.247 1.00 14.79 ? 503 SER A N 1 ATOM 4012 C CA . SER A 1 503 ? 8.320 -6.612 36.161 1.00 15.14 ? 503 SER A CA 1 ATOM 4013 C C . SER A 1 503 ? 8.429 -6.039 34.745 1.00 14.87 ? 503 SER A C 1 ATOM 4014 O O . SER A 1 503 ? 8.740 -4.858 34.554 1.00 15.54 ? 503 SER A O 1 ATOM 4015 C CB . SER A 1 503 ? 9.605 -7.274 36.647 1.00 15.77 ? 503 SER A CB 1 ATOM 4016 O OG . SER A 1 503 ? 9.907 -8.359 35.796 1.00 17.94 ? 503 SER A OG 1 ATOM 4017 N N . MET A 1 504 ? 8.146 -6.864 33.742 1.00 14.16 ? 504 MET A N 1 ATOM 4018 C CA . MET A 1 504 ? 8.150 -6.419 32.370 1.00 15.04 ? 504 MET A CA 1 ATOM 4019 C C . MET A 1 504 ? 7.083 -5.343 32.131 1.00 14.66 ? 504 MET A C 1 ATOM 4020 O O . MET A 1 504 ? 7.354 -4.324 31.506 1.00 13.88 ? 504 MET A O 1 ATOM 4021 C CB . MET A 1 504 ? 7.929 -7.576 31.410 1.00 14.43 ? 504 MET A CB 1 ATOM 4022 C CG . MET A 1 504 ? 8.103 -7.181 29.950 1.00 15.95 ? 504 MET A CG 1 ATOM 4023 S SD . MET A 1 504 ? 8.021 -8.600 28.882 1.00 16.21 ? 504 MET A SD 1 ATOM 4024 C CE . MET A 1 504 ? 8.416 -7.822 27.329 1.00 17.64 ? 504 MET A CE 1 ATOM 4025 N N . ALA A 1 505 ? 5.877 -5.590 32.628 1.00 13.79 ? 505 ALA A N 1 ATOM 4026 C CA . ALA A 1 505 ? 4.806 -4.570 32.472 1.00 13.76 ? 505 ALA A CA 1 ATOM 4027 C C . ALA A 1 505 ? 5.203 -3.251 33.182 1.00 14.48 ? 505 ALA A C 1 ATOM 4028 O O . ALA A 1 505 ? 4.958 -2.175 32.622 1.00 15.74 ? 505 ALA A O 1 ATOM 4029 C CB . ALA A 1 505 ? 3.450 -5.115 33.018 1.00 13.55 ? 505 ALA A CB 1 ATOM 4030 N N . VAL A 1 506 ? 5.826 -3.327 34.370 1.00 14.79 ? 506 VAL A N 1 ATOM 4031 C CA . VAL A 1 506 ? 6.259 -2.122 35.114 1.00 15.40 ? 506 VAL A CA 1 ATOM 4032 C C . VAL A 1 506 ? 7.297 -1.342 34.264 1.00 16.66 ? 506 VAL A C 1 ATOM 4033 O O . VAL A 1 506 ? 7.220 -0.118 34.076 1.00 15.21 ? 506 VAL A O 1 ATOM 4034 C CB . VAL A 1 506 ? 6.845 -2.487 36.557 1.00 15.86 ? 506 VAL A CB 1 ATOM 4035 C CG1 . VAL A 1 506 ? 7.539 -1.290 37.211 1.00 16.22 ? 506 VAL A CG1 1 ATOM 4036 C CG2 . VAL A 1 506 ? 5.747 -3.068 37.487 1.00 17.42 ? 506 VAL A CG2 1 ATOM 4037 N N . ALA A 1 507 ? 8.251 -2.085 33.700 1.00 17.01 ? 507 ALA A N 1 ATOM 4038 C CA . ALA A 1 507 ? 9.307 -1.506 32.836 1.00 17.11 ? 507 ALA A CA 1 ATOM 4039 C C . ALA A 1 507 ? 8.773 -0.916 31.544 1.00 17.16 ? 507 ALA A C 1 ATOM 4040 O O . ALA A 1 507 ? 9.296 0.085 31.055 1.00 16.40 ? 507 ALA A O 1 ATOM 4041 C CB . ALA A 1 507 ? 10.357 -2.593 32.518 1.00 17.59 ? 507 ALA A CB 1 ATOM 4042 N N . THR A 1 508 ? 7.730 -1.539 30.982 1.00 17.05 ? 508 THR A N 1 ATOM 4043 C CA . THR A 1 508 ? 7.072 -1.085 29.758 1.00 17.02 ? 508 THR A CA 1 ATOM 4044 C C . THR A 1 508 ? 6.252 0.192 30.002 1.00 17.27 ? 508 THR A C 1 ATOM 4045 O O . THR A 1 508 ? 6.287 1.119 29.182 1.00 16.45 ? 508 THR A O 1 ATOM 4046 C CB . THR A 1 508 ? 6.230 -2.245 29.107 1.00 17.14 ? 508 THR A CB 1 ATOM 4047 O OG1 . THR A 1 508 ? 7.120 -3.350 28.844 1.00 19.37 ? 508 THR A OG1 1 ATOM 4048 C CG2 . THR A 1 508 ? 5.619 -1.849 27.793 1.00 16.44 ? 508 THR A CG2 1 ATOM 4049 N N . ALA A 1 509 ? 5.551 0.250 31.133 1.00 17.66 ? 509 ALA A N 1 ATOM 4050 C CA . ALA A 1 509 ? 4.907 1.521 31.573 1.00 19.09 ? 509 ALA A CA 1 ATOM 4051 C C . ALA A 1 509 ? 5.961 2.610 31.787 1.00 19.95 ? 509 ALA A C 1 ATOM 4052 O O . ALA A 1 509 ? 5.765 3.761 31.402 1.00 20.59 ? 509 ALA A O 1 ATOM 4053 C CB . ALA A 1 509 ? 4.058 1.322 32.833 1.00 19.71 ? 509 ALA A CB 1 ATOM 4054 N N . GLU A 1 510 ? 7.114 2.251 32.341 1.00 21.27 ? 510 GLU A N 1 ATOM 4055 C CA . GLU A 1 510 ? 8.183 3.242 32.460 1.00 21.16 ? 510 GLU A CA 1 ATOM 4056 C C . GLU A 1 510 ? 8.632 3.764 31.101 1.00 19.87 ? 510 GLU A C 1 ATOM 4057 O O . GLU A 1 510 ? 8.773 4.976 30.941 1.00 19.20 ? 510 GLU A O 1 ATOM 4058 C CB . GLU A 1 510 ? 9.358 2.703 33.308 1.00 21.92 ? 510 GLU A CB 1 ATOM 4059 C CG . GLU A 1 510 ? 10.493 3.689 33.502 1.00 28.80 ? 510 GLU A CG 1 ATOM 4060 C CD . GLU A 1 510 ? 10.236 4.750 34.583 1.00 36.14 ? 510 GLU A CD 1 ATOM 4061 O OE1 . GLU A 1 510 ? 9.177 4.721 35.261 1.00 38.49 ? 510 GLU A OE1 1 ATOM 4062 O OE2 . GLU A 1 510 ? 11.127 5.618 34.761 1.00 38.73 ? 510 GLU A OE2 1 ATOM 4063 N N . ALA A 1 511 ? 8.858 2.861 30.134 1.00 19.23 ? 511 ALA A N 1 ATOM 4064 C CA . ALA A 1 511 ? 9.217 3.209 28.764 1.00 19.19 ? 511 ALA A CA 1 ATOM 4065 C C . ALA A 1 511 ? 8.171 4.131 28.134 1.00 20.17 ? 511 ALA A C 1 ATOM 4066 O O . ALA A 1 511 ? 8.508 5.081 27.411 1.00 18.84 ? 511 ALA A O 1 ATOM 4067 C CB . ALA A 1 511 ? 9.404 1.940 27.893 1.00 18.83 ? 511 ALA A CB 1 ATOM 4068 N N . ALA A 1 512 ? 6.902 3.877 28.432 1.00 19.76 ? 512 ALA A N 1 ATOM 4069 C CA . ALA A 1 512 ? 5.826 4.695 27.873 1.00 20.75 ? 512 ALA A CA 1 ATOM 4070 C C . ALA A 1 512 ? 5.897 6.160 28.346 1.00 21.20 ? 512 ALA A C 1 ATOM 4071 O O . ALA A 1 512 ? 5.455 7.050 27.632 1.00 21.70 ? 512 ALA A O 1 ATOM 4072 C CB . ALA A 1 512 ? 4.463 4.069 28.207 1.00 21.12 ? 512 ALA A CB 1 ATOM 4073 N N . LYS A 1 513 ? 6.483 6.411 29.523 1.00 22.06 ? 513 LYS A N 1 ATOM 4074 C CA . LYS A 1 513 ? 6.646 7.780 30.043 1.00 23.85 ? 513 LYS A CA 1 ATOM 4075 C C . LYS A 1 513 ? 7.441 8.660 29.080 1.00 24.33 ? 513 LYS A C 1 ATOM 4076 O O . LYS A 1 513 ? 7.202 9.863 28.975 1.00 24.17 ? 513 LYS A O 1 ATOM 4077 C CB . LYS A 1 513 ? 7.338 7.791 31.410 1.00 24.23 ? 513 LYS A CB 1 ATOM 4078 C CG . LYS A 1 513 ? 6.557 7.136 32.511 1.00 26.91 ? 513 LYS A CG 1 ATOM 4079 C CD . LYS A 1 513 ? 7.135 7.472 33.851 1.00 30.07 ? 513 LYS A CD 1 ATOM 4080 C CE . LYS A 1 513 ? 6.465 6.647 34.933 1.00 33.72 ? 513 LYS A CE 1 ATOM 4081 N NZ . LYS A 1 513 ? 7.284 6.650 36.167 1.00 37.19 ? 513 LYS A NZ 1 ATOM 4082 N N . THR A 1 514 ? 8.401 8.043 28.399 1.00 23.73 ? 514 THR A N 1 ATOM 4083 C CA . THR A 1 514 ? 9.286 8.726 27.450 1.00 22.97 ? 514 THR A CA 1 ATOM 4084 C C . THR A 1 514 ? 8.772 8.665 26.033 1.00 22.21 ? 514 THR A C 1 ATOM 4085 O O . THR A 1 514 ? 8.769 9.672 25.324 1.00 21.63 ? 514 THR A O 1 ATOM 4086 C CB . THR A 1 514 ? 10.682 8.062 27.513 1.00 23.22 ? 514 THR A CB 1 ATOM 4087 O OG1 . THR A 1 514 ? 11.201 8.275 28.822 1.00 24.24 ? 514 THR A OG1 1 ATOM 4088 C CG2 . THR A 1 514 ? 11.642 8.653 26.474 1.00 25.38 ? 514 THR A CG2 1 ATOM 4089 N N . VAL A 1 515 ? 8.313 7.481 25.610 1.00 20.55 ? 515 VAL A N 1 ATOM 4090 C CA . VAL A 1 515 ? 7.922 7.274 24.216 1.00 21.01 ? 515 VAL A CA 1 ATOM 4091 C C . VAL A 1 515 ? 6.576 7.972 23.916 1.00 20.77 ? 515 VAL A C 1 ATOM 4092 O O . VAL A 1 515 ? 6.370 8.490 22.822 1.00 20.52 ? 515 VAL A O 1 ATOM 4093 C CB . VAL A 1 515 ? 7.826 5.770 23.883 1.00 21.06 ? 515 VAL A CB 1 ATOM 4094 C CG1 . VAL A 1 515 ? 7.171 5.554 22.516 1.00 22.76 ? 515 VAL A CG1 1 ATOM 4095 C CG2 . VAL A 1 515 ? 9.219 5.120 23.918 1.00 23.57 ? 515 VAL A CG2 1 ATOM 4096 N N . PHE A 1 516 ? 5.704 8.011 24.921 1.00 20.24 ? 516 PHE A N 1 ATOM 4097 C CA . PHE A 1 516 ? 4.378 8.650 24.817 1.00 20.59 ? 516 PHE A CA 1 ATOM 4098 C C . PHE A 1 516 ? 4.163 9.676 25.930 1.00 21.62 ? 516 PHE A C 1 ATOM 4099 O O . PHE A 1 516 ? 3.379 9.427 26.870 1.00 21.60 ? 516 PHE A O 1 ATOM 4100 C CB . PHE A 1 516 ? 3.299 7.557 24.938 1.00 20.89 ? 516 PHE A CB 1 ATOM 4101 C CG . PHE A 1 516 ? 3.452 6.456 23.949 1.00 19.89 ? 516 PHE A CG 1 ATOM 4102 C CD1 . PHE A 1 516 ? 3.283 6.704 22.587 1.00 21.87 ? 516 PHE A CD1 1 ATOM 4103 C CD2 . PHE A 1 516 ? 3.756 5.165 24.374 1.00 21.72 ? 516 PHE A CD2 1 ATOM 4104 C CE1 . PHE A 1 516 ? 3.415 5.673 21.668 1.00 24.76 ? 516 PHE A CE1 1 ATOM 4105 C CE2 . PHE A 1 516 ? 3.874 4.128 23.462 1.00 23.52 ? 516 PHE A CE2 1 ATOM 4106 C CZ . PHE A 1 516 ? 3.703 4.383 22.109 1.00 20.31 ? 516 PHE A CZ 1 ATOM 4107 N N . PRO A 1 517 ? 4.874 10.827 25.876 1.00 22.48 ? 517 PRO A N 1 ATOM 4108 C CA . PRO A 1 517 ? 4.846 11.715 27.032 1.00 23.22 ? 517 PRO A CA 1 ATOM 4109 C C . PRO A 1 517 ? 3.432 12.183 27.407 1.00 22.46 ? 517 PRO A C 1 ATOM 4110 O O . PRO A 1 517 ? 2.704 12.676 26.555 1.00 23.46 ? 517 PRO A O 1 ATOM 4111 C CB . PRO A 1 517 ? 5.693 12.913 26.563 1.00 23.43 ? 517 PRO A CB 1 ATOM 4112 C CG . PRO A 1 517 ? 6.650 12.320 25.600 1.00 23.32 ? 517 PRO A CG 1 ATOM 4113 C CD . PRO A 1 517 ? 5.755 11.368 24.820 1.00 23.02 ? 517 PRO A CD 1 ATOM 4114 N N . ASN A 1 518 ? 3.106 12.015 28.681 1.00 23.05 ? 518 ASN A N 1 ATOM 4115 C CA . ASN A 1 518 ? 1.811 12.369 29.296 1.00 24.19 ? 518 ASN A CA 1 ATOM 4116 C C . ASN A 1 518 ? 0.592 11.665 28.711 1.00 22.78 ? 518 ASN A C 1 ATOM 4117 O O . ASN A 1 518 ? -0.540 12.108 28.949 1.00 23.62 ? 518 ASN A O 1 ATOM 4118 C CB . ASN A 1 518 ? 1.590 13.891 29.289 1.00 25.69 ? 518 ASN A CB 1 ATOM 4119 C CG . ASN A 1 518 ? 2.730 14.645 29.965 1.00 30.18 ? 518 ASN A CG 1 ATOM 4120 O OD1 . ASN A 1 518 ? 3.109 14.341 31.109 1.00 37.35 ? 518 ASN A OD1 1 ATOM 4121 N ND2 . ASN A 1 518 ? 3.281 15.633 29.259 1.00 33.36 ? 518 ASN A ND2 1 ATOM 4122 N N . LYS A 1 519 ? 0.811 10.597 27.951 1.00 21.14 ? 519 LYS A N 1 ATOM 4123 C CA . LYS A 1 519 ? -0.306 9.755 27.466 1.00 20.49 ? 519 LYS A CA 1 ATOM 4124 C C . LYS A 1 519 ? -0.340 8.396 28.156 1.00 19.74 ? 519 LYS A C 1 ATOM 4125 O O . LYS A 1 519 ? 0.683 7.885 28.671 1.00 18.67 ? 519 LYS A O 1 ATOM 4126 C CB . LYS A 1 519 ? -0.269 9.533 25.939 1.00 21.23 ? 519 LYS A CB 1 ATOM 4127 C CG . LYS A 1 519 ? -0.153 10.787 25.064 1.00 24.59 ? 519 LYS A CG 1 ATOM 4128 C CD . LYS A 1 519 ? -1.348 11.724 25.196 1.00 25.63 ? 519 LYS A CD 1 ATOM 4129 C CE . LYS A 1 519 ? -1.062 13.072 24.523 1.00 26.61 ? 519 LYS A CE 1 ATOM 4130 N NZ . LYS A 1 519 ? -2.076 14.101 24.882 1.00 32.53 ? 519 LYS A NZ 1 ATOM 4131 N N . ARG A 1 520 ? -1.523 7.783 28.118 1.00 16.54 ? 520 ARG A N 1 ATOM 4132 C CA . ARG A 1 520 ? -1.718 6.438 28.641 1.00 15.94 ? 520 ARG A CA 1 ATOM 4133 C C . ARG A 1 520 ? -1.151 5.364 27.771 1.00 15.49 ? 520 ARG A C 1 ATOM 4134 O O . ARG A 1 520 ? -0.652 4.366 28.305 1.00 16.83 ? 520 ARG A O 1 ATOM 4135 C CB . ARG A 1 520 ? -3.224 6.162 28.790 1.00 15.46 ? 520 ARG A CB 1 ATOM 4136 C CG . ARG A 1 520 ? -3.818 7.099 29.794 1.00 15.20 ? 520 ARG A CG 1 ATOM 4137 C CD . ARG A 1 520 ? -5.362 7.057 29.668 1.00 13.48 ? 520 ARG A CD 1 ATOM 4138 N NE . ARG A 1 520 ? -5.889 8.295 30.210 1.00 14.52 ? 520 ARG A NE 1 ATOM 4139 C CZ . ARG A 1 520 ? -7.180 8.624 30.247 1.00 16.74 ? 520 ARG A CZ 1 ATOM 4140 N NH1 . ARG A 1 520 ? -8.106 7.772 29.823 1.00 11.88 ? 520 ARG A NH1 1 ATOM 4141 N NH2 . ARG A 1 520 ? -7.528 9.800 30.713 1.00 15.34 ? 520 ARG A NH2 1 ATOM 4142 N N . SER A 1 521 ? -1.308 5.526 26.456 1.00 15.77 ? 521 SER A N 1 ATOM 4143 C CA . SER A 1 521 ? -0.956 4.498 25.467 1.00 15.72 ? 521 SER A CA 1 ATOM 4144 C C . SER A 1 521 ? -1.774 3.260 25.833 1.00 16.08 ? 521 SER A C 1 ATOM 4145 O O . SER A 1 521 ? -2.887 3.378 26.404 1.00 15.44 ? 521 SER A O 1 ATOM 4146 C CB . SER A 1 521 ? 0.564 4.231 25.536 1.00 16.03 ? 521 SER A CB 1 ATOM 4147 O OG . SER A 1 521 ? 0.961 3.264 24.579 1.00 14.46 ? 521 SER A OG 1 ATOM 4148 N N . PHE A 1 522 ? -1.210 2.080 25.628 1.00 15.48 ? 522 PHE A N 1 ATOM 4149 C CA . PHE A 1 522 ? -1.932 0.818 25.911 1.00 14.93 ? 522 PHE A CA 1 ATOM 4150 C C . PHE A 1 522 ? -0.856 -0.256 26.037 1.00 15.15 ? 522 PHE A C 1 ATOM 4151 O O . PHE A 1 522 ? -0.002 -0.343 25.159 1.00 15.11 ? 522 PHE A O 1 ATOM 4152 C CB . PHE A 1 522 ? -2.797 0.500 24.691 1.00 14.51 ? 522 PHE A CB 1 ATOM 4153 C CG . PHE A 1 522 ? -3.405 -0.888 24.670 1.00 16.64 ? 522 PHE A CG 1 ATOM 4154 C CD1 . PHE A 1 522 ? -4.499 -1.193 25.474 1.00 17.06 ? 522 PHE A CD1 1 ATOM 4155 C CD2 . PHE A 1 522 ? -2.914 -1.867 23.791 1.00 16.34 ? 522 PHE A CD2 1 ATOM 4156 C CE1 . PHE A 1 522 ? -5.083 -2.503 25.428 1.00 17.23 ? 522 PHE A CE1 1 ATOM 4157 C CE2 . PHE A 1 522 ? -3.505 -3.141 23.711 1.00 16.43 ? 522 PHE A CE2 1 ATOM 4158 C CZ . PHE A 1 522 ? -4.580 -3.456 24.546 1.00 15.16 ? 522 PHE A CZ 1 ATOM 4159 N N . ILE A 1 523 ? -0.886 -1.040 27.111 1.00 14.11 ? 523 ILE A N 1 ATOM 4160 C CA . ILE A 1 523 ? -0.032 -2.222 27.235 1.00 14.22 ? 523 ILE A CA 1 ATOM 4161 C C . ILE A 1 523 ? -0.891 -3.428 27.445 1.00 14.53 ? 523 ILE A C 1 ATOM 4162 O O . ILE A 1 523 ? -1.775 -3.423 28.310 1.00 14.46 ? 523 ILE A O 1 ATOM 4163 C CB . ILE A 1 523 ? 0.939 -2.108 28.409 1.00 14.05 ? 523 ILE A CB 1 ATOM 4164 C CG1 . ILE A 1 523 ? 1.832 -0.852 28.217 1.00 13.54 ? 523 ILE A CG1 1 ATOM 4165 C CG2 . ILE A 1 523 ? 1.760 -3.407 28.552 1.00 14.12 ? 523 ILE A CG2 1 ATOM 4166 C CD1 . ILE A 1 523 ? 2.442 -0.407 29.499 1.00 19.16 ? 523 ILE A CD1 1 ATOM 4167 N N . LEU A 1 524 ? -0.648 -4.458 26.645 1.00 14.34 ? 524 LEU A N 1 ATOM 4168 C CA . LEU A 1 524 ? -1.384 -5.751 26.755 1.00 13.53 ? 524 LEU A CA 1 ATOM 4169 C C . LEU A 1 524 ? -0.361 -6.806 27.155 1.00 14.37 ? 524 LEU A C 1 ATOM 4170 O O . LEU A 1 524 ? 0.635 -6.973 26.449 1.00 15.25 ? 524 LEU A O 1 ATOM 4171 C CB . LEU A 1 524 ? -1.991 -6.126 25.411 1.00 12.83 ? 524 LEU A CB 1 ATOM 4172 C CG . LEU A 1 524 ? -2.806 -7.430 25.277 1.00 14.37 ? 524 LEU A CG 1 ATOM 4173 C CD1 . LEU A 1 524 ? -4.089 -7.379 26.174 1.00 14.48 ? 524 LEU A CD1 1 ATOM 4174 C CD2 . LEU A 1 524 ? -3.159 -7.729 23.839 1.00 13.26 ? 524 LEU A CD2 1 ATOM 4175 N N . THR A 1 525 ? -0.593 -7.528 28.245 1.00 13.78 ? 525 THR A N 1 ATOM 4176 C CA . THR A 1 525 ? 0.413 -8.518 28.737 1.00 14.43 ? 525 THR A CA 1 ATOM 4177 C C . THR A 1 525 ? -0.161 -9.913 28.832 1.00 15.84 ? 525 THR A C 1 ATOM 4178 O O . THR A 1 525 ? -1.359 -10.084 29.121 1.00 15.07 ? 525 THR A O 1 ATOM 4179 C CB . THR A 1 525 ? 1.047 -8.102 30.102 1.00 14.62 ? 525 THR A CB 1 ATOM 4180 O OG1 . THR A 1 525 ? 2.156 -8.975 30.420 1.00 15.79 ? 525 THR A OG1 1 ATOM 4181 C CG2 . THR A 1 525 ? 0.004 -8.133 31.253 1.00 12.79 ? 525 THR A CG2 1 ATOM 4182 N N . ARG A 1 526 ? 0.690 -10.907 28.585 1.00 15.81 ? 526 ARG A N 1 ATOM 4183 C CA . ARG A 1 526 ? 0.294 -12.305 28.789 1.00 16.90 ? 526 ARG A CA 1 ATOM 4184 C C . ARG A 1 526 ? 0.432 -12.690 30.255 1.00 16.58 ? 526 ARG A C 1 ATOM 4185 O O . ARG A 1 526 ? -0.573 -12.963 30.922 1.00 16.42 ? 526 ARG A O 1 ATOM 4186 C CB . ARG A 1 526 ? 1.077 -13.281 27.884 1.00 16.61 ? 526 ARG A CB 1 ATOM 4187 C CG . ARG A 1 526 ? 0.281 -14.612 27.720 1.00 17.44 ? 526 ARG A CG 1 ATOM 4188 C CD . ARG A 1 526 ? 0.714 -15.348 26.516 1.00 18.61 ? 526 ARG A CD 1 ATOM 4189 N NE . ARG A 1 526 ? 1.930 -16.089 26.786 1.00 21.24 ? 526 ARG A NE 1 ATOM 4190 C CZ . ARG A 1 526 ? 2.635 -16.744 25.872 1.00 22.51 ? 526 ARG A CZ 1 ATOM 4191 N NH1 . ARG A 1 526 ? 2.298 -16.684 24.587 1.00 21.88 ? 526 ARG A NH1 1 ATOM 4192 N NH2 . ARG A 1 526 ? 3.718 -17.413 26.247 1.00 21.00 ? 526 ARG A NH2 1 ATOM 4193 N N . SER A 1 527 ? 1.673 -12.735 30.756 1.00 15.77 ? 527 SER A N 1 ATOM 4194 C CA . SER A 1 527 ? 1.903 -13.084 32.149 1.00 16.00 ? 527 SER A CA 1 ATOM 4195 C C . SER A 1 527 ? 1.561 -11.926 33.091 1.00 15.29 ? 527 SER A C 1 ATOM 4196 O O . SER A 1 527 ? 1.820 -10.765 32.770 1.00 16.37 ? 527 SER A O 1 ATOM 4197 C CB . SER A 1 527 ? 3.364 -13.491 32.387 1.00 16.53 ? 527 SER A CB 1 ATOM 4198 O OG . SER A 1 527 ? 3.399 -14.260 33.555 1.00 20.30 ? 527 SER A OG 1 ATOM 4199 N N . THR A 1 528 ? 0.967 -12.252 34.225 1.00 14.38 ? 528 THR A N 1 ATOM 4200 C CA . THR A 1 528 ? 0.592 -11.250 35.239 1.00 15.11 ? 528 THR A CA 1 ATOM 4201 C C . THR A 1 528 ? 0.936 -11.761 36.621 1.00 15.06 ? 528 THR A C 1 ATOM 4202 O O . THR A 1 528 ? 1.089 -12.959 36.816 1.00 15.81 ? 528 THR A O 1 ATOM 4203 C CB . THR A 1 528 ? -0.957 -10.951 35.235 1.00 14.41 ? 528 THR A CB 1 ATOM 4204 O OG1 . THR A 1 528 ? -1.669 -12.127 35.583 1.00 15.47 ? 528 THR A OG1 1 ATOM 4205 C CG2 . THR A 1 528 ? -1.425 -10.452 33.866 1.00 16.32 ? 528 THR A CG2 1 ATOM 4206 N N . PHE A 1 529 ? 0.984 -10.857 37.601 1.00 13.08 ? 529 PHE A N 1 ATOM 4207 C CA . PHE A 1 529 ? 1.007 -11.206 38.989 1.00 13.44 ? 529 PHE A CA 1 ATOM 4208 C C . PHE A 1 529 ? -0.062 -10.280 39.597 1.00 13.77 ? 529 PHE A C 1 ATOM 4209 O O . PHE A 1 529 ? -0.591 -9.424 38.916 1.00 14.05 ? 529 PHE A O 1 ATOM 4210 C CB . PHE A 1 529 ? 2.389 -10.904 39.617 1.00 13.03 ? 529 PHE A CB 1 ATOM 4211 C CG . PHE A 1 529 ? 2.550 -11.384 41.033 1.00 12.95 ? 529 PHE A CG 1 ATOM 4212 C CD1 . PHE A 1 529 ? 2.685 -12.728 41.316 1.00 14.59 ? 529 PHE A CD1 1 ATOM 4213 C CD2 . PHE A 1 529 ? 2.567 -10.478 42.086 1.00 14.79 ? 529 PHE A CD2 1 ATOM 4214 C CE1 . PHE A 1 529 ? 2.834 -13.177 42.633 1.00 15.98 ? 529 PHE A CE1 1 ATOM 4215 C CE2 . PHE A 1 529 ? 2.725 -10.895 43.399 1.00 14.99 ? 529 PHE A CE2 1 ATOM 4216 C CZ . PHE A 1 529 ? 2.839 -12.267 43.685 1.00 16.71 ? 529 PHE A CZ 1 ATOM 4217 N N . ALA A 1 530 ? -0.314 -10.428 40.874 1.00 13.54 ? 530 ALA A N 1 ATOM 4218 C CA . ALA A 1 530 ? -1.270 -9.550 41.572 1.00 15.14 ? 530 ALA A CA 1 ATOM 4219 C C . ALA A 1 530 ? -0.811 -8.098 41.417 1.00 15.11 ? 530 ALA A C 1 ATOM 4220 O O . ALA A 1 530 ? 0.337 -7.783 41.712 1.00 16.44 ? 530 ALA A O 1 ATOM 4221 C CB . ALA A 1 530 ? -1.278 -9.925 43.025 1.00 14.38 ? 530 ALA A CB 1 ATOM 4222 N N . GLY A 1 531 ? -1.684 -7.214 40.946 1.00 15.05 ? 531 GLY A N 1 ATOM 4223 C CA . GLY A 1 531 ? -1.270 -5.806 40.706 1.00 14.00 ? 531 GLY A CA 1 ATOM 4224 C C . GLY A 1 531 ? -0.914 -5.441 39.272 1.00 13.41 ? 531 GLY A C 1 ATOM 4225 O O . GLY A 1 531 ? -0.737 -4.279 38.980 1.00 12.89 ? 531 GLY A O 1 ATOM 4226 N N . SER A 1 532 ? -0.838 -6.418 38.361 1.00 13.38 ? 532 SER A N 1 ATOM 4227 C CA . SER A 1 532 ? -0.498 -6.134 36.957 1.00 12.89 ? 532 SER A CA 1 ATOM 4228 C C . SER A 1 532 ? -1.465 -5.191 36.257 1.00 13.17 ? 532 SER A C 1 ATOM 4229 O O . SER A 1 532 ? -1.068 -4.495 35.326 1.00 12.09 ? 532 SER A O 1 ATOM 4230 C CB . SER A 1 532 ? -0.330 -7.388 36.094 1.00 13.42 ? 532 SER A CB 1 ATOM 4231 O OG . SER A 1 532 ? 0.895 -8.076 36.395 1.00 13.48 ? 532 SER A OG 1 ATOM 4232 N N . GLY A 1 533 ? -2.731 -5.222 36.660 1.00 13.58 ? 533 GLY A N 1 ATOM 4233 C CA . GLY A 1 533 ? -3.731 -4.313 36.063 1.00 13.37 ? 533 GLY A CA 1 ATOM 4234 C C . GLY A 1 533 ? -3.452 -2.808 36.198 1.00 13.62 ? 533 GLY A C 1 ATOM 4235 O O . GLY A 1 533 ? -4.033 -1.980 35.454 1.00 13.22 ? 533 GLY A O 1 ATOM 4236 N N . LYS A 1 534 ? -2.628 -2.431 37.175 1.00 13.18 ? 534 LYS A N 1 ATOM 4237 C CA . LYS A 1 534 ? -2.188 -1.036 37.328 1.00 14.42 ? 534 LYS A CA 1 ATOM 4238 C C . LYS A 1 534 ? -1.456 -0.543 36.086 1.00 15.40 ? 534 LYS A C 1 ATOM 4239 O O . LYS A 1 534 ? -1.395 0.650 35.815 1.00 16.72 ? 534 LYS A O 1 ATOM 4240 C CB . LYS A 1 534 ? -1.320 -0.908 38.585 1.00 14.24 ? 534 LYS A CB 1 ATOM 4241 C CG . LYS A 1 534 ? -0.682 0.452 38.845 1.00 16.46 ? 534 LYS A CG 1 ATOM 4242 C CD . LYS A 1 534 ? -0.058 0.534 40.237 1.00 16.26 ? 534 LYS A CD 1 ATOM 4243 C CE . LYS A 1 534 ? 0.805 1.816 40.364 1.00 22.35 ? 534 LYS A CE 1 ATOM 4244 N NZ . LYS A 1 534 ? 1.553 1.825 41.655 1.00 23.67 ? 534 LYS A NZ 1 ATOM 4245 N N . PHE A 1 535 ? -0.875 -1.489 35.354 1.00 15.00 ? 535 PHE A N 1 ATOM 4246 C CA . PHE A 1 535 ? -0.052 -1.236 34.175 1.00 14.47 ? 535 PHE A CA 1 ATOM 4247 C C . PHE A 1 535 ? -0.644 -1.705 32.868 1.00 14.93 ? 535 PHE A C 1 ATOM 4248 O O . PHE A 1 535 ? -0.394 -1.097 31.826 1.00 15.28 ? 535 PHE A O 1 ATOM 4249 C CB . PHE A 1 535 ? 1.319 -1.910 34.389 1.00 15.42 ? 535 PHE A CB 1 ATOM 4250 C CG . PHE A 1 535 ? 1.963 -1.493 35.676 1.00 17.43 ? 535 PHE A CG 1 ATOM 4251 C CD1 . PHE A 1 535 ? 2.578 -0.266 35.778 1.00 18.27 ? 535 PHE A CD1 1 ATOM 4252 C CD2 . PHE A 1 535 ? 1.897 -2.300 36.808 1.00 20.96 ? 535 PHE A CD2 1 ATOM 4253 C CE1 . PHE A 1 535 ? 3.126 0.164 36.998 1.00 20.94 ? 535 PHE A CE1 1 ATOM 4254 C CE2 . PHE A 1 535 ? 2.440 -1.866 38.016 1.00 22.09 ? 535 PHE A CE2 1 ATOM 4255 C CZ . PHE A 1 535 ? 3.060 -0.630 38.094 1.00 18.69 ? 535 PHE A CZ 1 ATOM 4256 N N . ALA A 1 536 ? -1.434 -2.781 32.884 1.00 14.49 ? 536 ALA A N 1 ATOM 4257 C CA . ALA A 1 536 ? -1.693 -3.442 31.633 1.00 13.79 ? 536 ALA A CA 1 ATOM 4258 C C . ALA A 1 536 ? -3.061 -4.119 31.572 1.00 13.67 ? 536 ALA A C 1 ATOM 4259 O O . ALA A 1 536 ? -3.614 -4.461 32.598 1.00 13.67 ? 536 ALA A O 1 ATOM 4260 C CB . ALA A 1 536 ? -0.571 -4.493 31.371 1.00 15.04 ? 536 ALA A CB 1 ATOM 4261 N N . ALA A 1 537 ? -3.579 -4.254 30.359 1.00 12.73 ? 537 ALA A N 1 ATOM 4262 C CA . ALA A 1 537 ? -4.658 -5.187 30.018 1.00 13.37 ? 537 ALA A CA 1 ATOM 4263 C C . ALA A 1 537 ? -4.095 -6.629 29.911 1.00 13.97 ? 537 ALA A C 1 ATOM 4264 O O . ALA A 1 537 ? -2.882 -6.850 29.865 1.00 14.01 ? 537 ALA A O 1 ATOM 4265 C CB . ALA A 1 537 ? -5.258 -4.788 28.675 1.00 12.48 ? 537 ALA A CB 1 ATOM 4266 N N . HIS A 1 538 ? -4.993 -7.593 29.784 1.00 13.89 ? 538 HIS A N 1 ATOM 4267 C CA . HIS A 1 538 ? -4.597 -8.988 29.664 1.00 14.39 ? 538 HIS A CA 1 ATOM 4268 C C . HIS A 1 538 ? -5.479 -9.665 28.626 1.00 14.74 ? 538 HIS A C 1 ATOM 4269 O O . HIS A 1 538 ? -6.636 -9.276 28.437 1.00 14.47 ? 538 HIS A O 1 ATOM 4270 C CB . HIS A 1 538 ? -4.709 -9.681 31.042 1.00 13.48 ? 538 HIS A CB 1 ATOM 4271 C CG . HIS A 1 538 ? -4.500 -11.169 31.013 1.00 13.20 ? 538 HIS A CG 1 ATOM 4272 N ND1 . HIS A 1 538 ? -3.313 -11.748 30.608 1.00 12.71 ? 538 HIS A ND1 1 ATOM 4273 C CD2 . HIS A 1 538 ? -5.331 -12.198 31.334 1.00 12.15 ? 538 HIS A CD2 1 ATOM 4274 C CE1 . HIS A 1 538 ? -3.412 -13.068 30.714 1.00 14.23 ? 538 HIS A CE1 1 ATOM 4275 N NE2 . HIS A 1 538 ? -4.629 -13.368 31.150 1.00 14.70 ? 538 HIS A NE2 1 ATOM 4276 N N . TRP A 1 539 ? -4.932 -10.644 27.902 1.00 14.16 ? 539 TRP A N 1 ATOM 4277 C CA . TRP A 1 539 ? -5.787 -11.545 27.139 1.00 15.03 ? 539 TRP A CA 1 ATOM 4278 C C . TRP A 1 539 ? -5.586 -12.984 27.589 1.00 15.56 ? 539 TRP A C 1 ATOM 4279 O O . TRP A 1 539 ? -4.524 -13.354 28.112 1.00 15.60 ? 539 TRP A O 1 ATOM 4280 C CB . TRP A 1 539 ? -5.669 -11.372 25.594 1.00 15.54 ? 539 TRP A CB 1 ATOM 4281 C CG . TRP A 1 539 ? -4.587 -12.217 24.934 1.00 15.21 ? 539 TRP A CG 1 ATOM 4282 C CD1 . TRP A 1 539 ? -4.771 -13.284 24.091 1.00 16.04 ? 539 TRP A CD1 1 ATOM 4283 C CD2 . TRP A 1 539 ? -3.176 -12.033 25.047 1.00 15.83 ? 539 TRP A CD2 1 ATOM 4284 N NE1 . TRP A 1 539 ? -3.555 -13.773 23.673 1.00 18.46 ? 539 TRP A NE1 1 ATOM 4285 C CE2 . TRP A 1 539 ? -2.557 -13.028 24.245 1.00 17.13 ? 539 TRP A CE2 1 ATOM 4286 C CE3 . TRP A 1 539 ? -2.377 -11.103 25.720 1.00 16.59 ? 539 TRP A CE3 1 ATOM 4287 C CZ2 . TRP A 1 539 ? -1.169 -13.141 24.120 1.00 17.23 ? 539 TRP A CZ2 1 ATOM 4288 C CZ3 . TRP A 1 539 ? -0.979 -11.230 25.616 1.00 16.80 ? 539 TRP A CZ3 1 ATOM 4289 C CH2 . TRP A 1 539 ? -0.403 -12.249 24.822 1.00 16.30 ? 539 TRP A CH2 1 ATOM 4290 N N . LEU A 1 540 ? -6.598 -13.809 27.375 1.00 15.92 ? 540 LEU A N 1 ATOM 4291 C CA . LEU A 1 540 ? -6.633 -15.112 28.025 1.00 16.45 ? 540 LEU A CA 1 ATOM 4292 C C . LEU A 1 540 ? -5.774 -16.158 27.301 1.00 16.98 ? 540 LEU A C 1 ATOM 4293 O O . LEU A 1 540 ? -5.784 -17.320 27.666 1.00 18.31 ? 540 LEU A O 1 ATOM 4294 C CB . LEU A 1 540 ? -8.081 -15.576 28.210 1.00 16.59 ? 540 LEU A CB 1 ATOM 4295 C CG . LEU A 1 540 ? -8.861 -14.653 29.155 1.00 18.36 ? 540 LEU A CG 1 ATOM 4296 C CD1 . LEU A 1 540 ? -10.336 -14.989 29.041 1.00 19.67 ? 540 LEU A CD1 1 ATOM 4297 C CD2 . LEU A 1 540 ? -8.385 -14.732 30.608 1.00 17.61 ? 540 LEU A CD2 1 ATOM 4298 N N . GLY A 1 541 ? -5.002 -15.720 26.308 1.00 16.93 ? 541 GLY A N 1 ATOM 4299 C CA . GLY A 1 541 ? -3.931 -16.552 25.722 1.00 16.60 ? 541 GLY A CA 1 ATOM 4300 C C . GLY A 1 541 ? -4.360 -17.326 24.503 1.00 16.87 ? 541 GLY A C 1 ATOM 4301 O O . GLY A 1 541 ? -5.333 -16.944 23.837 1.00 15.90 ? 541 GLY A O 1 ATOM 4302 N N . ASP A 1 542 ? -3.655 -18.434 24.238 1.00 16.23 ? 542 ASP A N 1 ATOM 4303 C CA . ASP A 1 542 ? -3.767 -19.202 22.991 1.00 16.97 ? 542 ASP A CA 1 ATOM 4304 C C . ASP A 1 542 ? -4.909 -20.209 23.051 1.00 17.23 ? 542 ASP A C 1 ATOM 4305 O O . ASP A 1 542 ? -4.682 -21.413 23.158 1.00 17.57 ? 542 ASP A O 1 ATOM 4306 C CB . ASP A 1 542 ? -2.451 -19.952 22.692 1.00 17.19 ? 542 ASP A CB 1 ATOM 4307 C CG . ASP A 1 542 ? -1.270 -19.018 22.548 1.00 20.31 ? 542 ASP A CG 1 ATOM 4308 O OD1 . ASP A 1 542 ? -1.480 -17.806 22.270 1.00 22.67 ? 542 ASP A OD1 1 ATOM 4309 O OD2 . ASP A 1 542 ? -0.116 -19.521 22.672 1.00 24.54 ? 542 ASP A OD2 1 ATOM 4310 N N . ASN A 1 543 ? -6.136 -19.704 22.988 1.00 15.44 ? 543 ASN A N 1 ATOM 4311 C CA . ASN A 1 543 ? -7.303 -20.562 23.029 1.00 16.19 ? 543 ASN A CA 1 ATOM 4312 C C . ASN A 1 543 ? -7.501 -21.278 21.671 1.00 16.57 ? 543 ASN A C 1 ATOM 4313 O O . ASN A 1 543 ? -6.644 -21.233 20.779 1.00 17.60 ? 543 ASN A O 1 ATOM 4314 C CB . ASN A 1 543 ? -8.545 -19.742 23.472 1.00 13.95 ? 543 ASN A CB 1 ATOM 4315 C CG . ASN A 1 543 ? -8.972 -18.730 22.424 1.00 15.00 ? 543 ASN A CG 1 ATOM 4316 O OD1 . ASN A 1 543 ? -8.273 -18.542 21.433 1.00 13.53 ? 543 ASN A OD1 1 ATOM 4317 N ND2 . ASN A 1 543 ? -10.144 -18.095 22.605 1.00 14.42 ? 543 ASN A ND2 1 ATOM 4318 N N . THR A 1 544 ? -8.625 -21.974 21.529 1.00 17.81 ? 544 THR A N 1 ATOM 4319 C CA . THR A 1 544 ? -8.868 -22.820 20.367 1.00 18.26 ? 544 THR A CA 1 ATOM 4320 C C . THR A 1 544 ? -10.263 -22.502 19.866 1.00 18.51 ? 544 THR A C 1 ATOM 4321 O O . THR A 1 544 ? -11.108 -22.068 20.642 1.00 18.27 ? 544 THR A O 1 ATOM 4322 C CB . THR A 1 544 ? -8.716 -24.306 20.772 1.00 19.51 ? 544 THR A CB 1 ATOM 4323 O OG1 . THR A 1 544 ? -7.459 -24.441 21.449 1.00 19.80 ? 544 THR A OG1 1 ATOM 4324 C CG2 . THR A 1 544 ? -8.681 -25.247 19.570 1.00 19.97 ? 544 THR A CG2 1 ATOM 4325 N N . ALA A 1 545 ? -10.475 -22.668 18.563 1.00 17.57 ? 545 ALA A N 1 ATOM 4326 C CA . ALA A 1 545 ? -11.759 -22.433 17.929 1.00 17.71 ? 545 ALA A CA 1 ATOM 4327 C C . ALA A 1 545 ? -12.765 -23.559 18.216 1.00 18.56 ? 545 ALA A C 1 ATOM 4328 O O . ALA A 1 545 ? -13.101 -24.365 17.332 1.00 18.45 ? 545 ALA A O 1 ATOM 4329 C CB . ALA A 1 545 ? -11.546 -22.234 16.431 1.00 18.88 ? 545 ALA A CB 1 ATOM 4330 N N . THR A 1 546 ? -13.227 -23.621 19.465 1.00 17.11 ? 546 THR A N 1 ATOM 4331 C CA . THR A 1 546 ? -14.215 -24.645 19.861 1.00 17.51 ? 546 THR A CA 1 ATOM 4332 C C . THR A 1 546 ? -15.327 -24.015 20.696 1.00 16.16 ? 546 THR A C 1 ATOM 4333 O O . THR A 1 546 ? -15.157 -22.960 21.281 1.00 13.53 ? 546 THR A O 1 ATOM 4334 C CB . THR A 1 546 ? -13.649 -25.835 20.692 1.00 17.48 ? 546 THR A CB 1 ATOM 4335 O OG1 . THR A 1 546 ? -13.456 -25.472 22.080 1.00 20.80 ? 546 THR A OG1 1 ATOM 4336 C CG2 . THR A 1 546 ? -12.353 -26.421 20.109 1.00 18.70 ? 546 THR A CG2 1 ATOM 4337 N N . TRP A 1 547 ? -16.465 -24.690 20.764 1.00 16.40 ? 547 TRP A N 1 ATOM 4338 C CA . TRP A 1 547 ? -17.537 -24.191 21.599 1.00 16.88 ? 547 TRP A CA 1 ATOM 4339 C C . TRP A 1 547 ? -17.173 -24.214 23.094 1.00 16.94 ? 547 TRP A C 1 ATOM 4340 O O . TRP A 1 547 ? -17.633 -23.370 23.840 1.00 16.19 ? 547 TRP A O 1 ATOM 4341 C CB . TRP A 1 547 ? -18.822 -24.973 21.329 1.00 17.11 ? 547 TRP A CB 1 ATOM 4342 C CG . TRP A 1 547 ? -19.335 -24.650 19.952 1.00 17.54 ? 547 TRP A CG 1 ATOM 4343 C CD1 . TRP A 1 547 ? -18.970 -25.247 18.766 1.00 19.93 ? 547 TRP A CD1 1 ATOM 4344 C CD2 . TRP A 1 547 ? -20.241 -23.601 19.616 1.00 18.37 ? 547 TRP A CD2 1 ATOM 4345 N NE1 . TRP A 1 547 ? -19.657 -24.670 17.717 1.00 20.09 ? 547 TRP A NE1 1 ATOM 4346 C CE2 . TRP A 1 547 ? -20.433 -23.645 18.211 1.00 19.54 ? 547 TRP A CE2 1 ATOM 4347 C CE3 . TRP A 1 547 ? -20.933 -22.634 20.371 1.00 17.38 ? 547 TRP A CE3 1 ATOM 4348 C CZ2 . TRP A 1 547 ? -21.284 -22.742 17.534 1.00 19.90 ? 547 TRP A CZ2 1 ATOM 4349 C CZ3 . TRP A 1 547 ? -21.785 -21.743 19.707 1.00 17.79 ? 547 TRP A CZ3 1 ATOM 4350 C CH2 . TRP A 1 547 ? -21.953 -21.804 18.295 1.00 18.05 ? 547 TRP A CH2 1 ATOM 4351 N N . ASP A 1 548 ? -16.356 -25.176 23.525 1.00 16.17 ? 548 ASP A N 1 ATOM 4352 C CA . ASP A 1 548 ? -15.908 -25.222 24.917 1.00 16.89 ? 548 ASP A CA 1 ATOM 4353 C C . ASP A 1 548 ? -15.161 -23.944 25.270 1.00 16.76 ? 548 ASP A C 1 ATOM 4354 O O . ASP A 1 548 ? -15.468 -23.342 26.280 1.00 15.80 ? 548 ASP A O 1 ATOM 4355 C CB . ASP A 1 548 ? -14.966 -26.389 25.177 1.00 17.56 ? 548 ASP A CB 1 ATOM 4356 C CG . ASP A 1 548 ? -15.693 -27.684 25.466 1.00 22.25 ? 548 ASP A CG 1 ATOM 4357 O OD1 . ASP A 1 548 ? -16.860 -27.666 25.937 1.00 23.65 ? 548 ASP A OD1 1 ATOM 4358 O OD2 . ASP A 1 548 ? -15.042 -28.722 25.253 1.00 26.13 ? 548 ASP A OD2 1 ATOM 4359 N N . ASP A 1 549 ? -14.198 -23.551 24.423 1.00 15.51 ? 549 ASP A N 1 ATOM 4360 C CA . ASP A 1 549 ? -13.399 -22.329 24.648 1.00 15.57 ? 549 ASP A CA 1 ATOM 4361 C C . ASP A 1 549 ? -14.279 -21.076 24.694 1.00 14.97 ? 549 ASP A C 1 ATOM 4362 O O . ASP A 1 549 ? -14.059 -20.189 25.511 1.00 13.92 ? 549 ASP A O 1 ATOM 4363 C CB . ASP A 1 549 ? -12.322 -22.144 23.565 1.00 15.37 ? 549 ASP A CB 1 ATOM 4364 C CG . ASP A 1 549 ? -11.179 -23.189 23.645 1.00 18.74 ? 549 ASP A CG 1 ATOM 4365 O OD1 . ASP A 1 549 ? -10.030 -22.839 24.035 1.00 20.75 ? 549 ASP A OD1 1 ATOM 4366 O OD2 . ASP A 1 549 ? -11.424 -24.368 23.271 1.00 24.17 ? 549 ASP A OD2 1 ATOM 4367 N N . LEU A 1 550 ? -15.296 -21.010 23.836 1.00 14.28 ? 550 LEU A N 1 ATOM 4368 C CA . LEU A 1 550 ? -16.248 -19.900 23.916 1.00 15.26 ? 550 LEU A CA 1 ATOM 4369 C C . LEU A 1 550 ? -16.909 -19.831 25.322 1.00 15.75 ? 550 LEU A C 1 ATOM 4370 O O . LEU A 1 550 ? -16.939 -18.782 25.964 1.00 16.10 ? 550 LEU A O 1 ATOM 4371 C CB . LEU A 1 550 ? -17.298 -20.062 22.806 1.00 15.36 ? 550 LEU A CB 1 ATOM 4372 C CG . LEU A 1 550 ? -18.508 -19.144 22.888 1.00 17.26 ? 550 LEU A CG 1 ATOM 4373 C CD1 . LEU A 1 550 ? -18.083 -17.741 22.625 1.00 18.75 ? 550 LEU A CD1 1 ATOM 4374 C CD2 . LEU A 1 550 ? -19.616 -19.585 21.941 1.00 18.26 ? 550 LEU A CD2 1 ATOM 4375 N N . ARG A 1 551 ? -17.455 -20.958 25.797 1.00 16.23 ? 551 ARG A N 1 ATOM 4376 C CA . ARG A 1 551 ? -18.078 -21.008 27.118 1.00 16.17 ? 551 ARG A CA 1 ATOM 4377 C C . ARG A 1 551 ? -17.060 -20.693 28.241 1.00 15.79 ? 551 ARG A C 1 ATOM 4378 O O . ARG A 1 551 ? -17.371 -19.978 29.190 1.00 17.16 ? 551 ARG A O 1 ATOM 4379 C CB . ARG A 1 551 ? -18.701 -22.388 27.339 1.00 16.67 ? 551 ARG A CB 1 ATOM 4380 C CG . ARG A 1 551 ? -19.987 -22.613 26.508 1.00 15.22 ? 551 ARG A CG 1 ATOM 4381 C CD . ARG A 1 551 ? -20.615 -23.989 26.796 1.00 18.92 ? 551 ARG A CD 1 ATOM 4382 N NE . ARG A 1 551 ? -19.843 -25.124 26.291 1.00 19.84 ? 551 ARG A NE 1 ATOM 4383 C CZ . ARG A 1 551 ? -19.994 -25.710 25.096 1.00 22.17 ? 551 ARG A CZ 1 ATOM 4384 N NH1 . ARG A 1 551 ? -20.874 -25.276 24.192 1.00 19.45 ? 551 ARG A NH1 1 ATOM 4385 N NH2 . ARG A 1 551 ? -19.252 -26.757 24.790 1.00 21.46 ? 551 ARG A NH2 1 ATOM 4386 N N . TRP A 1 552 ? -15.855 -21.218 28.119 1.00 15.14 ? 552 TRP A N 1 ATOM 4387 C CA . TRP A 1 552 ? -14.844 -21.080 29.192 1.00 15.29 ? 552 TRP A CA 1 ATOM 4388 C C . TRP A 1 552 ? -14.314 -19.657 29.313 1.00 15.98 ? 552 TRP A C 1 ATOM 4389 O O . TRP A 1 552 ? -13.686 -19.291 30.336 1.00 16.13 ? 552 TRP A O 1 ATOM 4390 C CB . TRP A 1 552 ? -13.670 -22.009 28.900 1.00 15.80 ? 552 TRP A CB 1 ATOM 4391 C CG . TRP A 1 552 ? -14.037 -23.450 28.997 1.00 17.75 ? 552 TRP A CG 1 ATOM 4392 C CD1 . TRP A 1 552 ? -15.103 -23.975 29.648 1.00 17.57 ? 552 TRP A CD1 1 ATOM 4393 C CD2 . TRP A 1 552 ? -13.290 -24.556 28.467 1.00 18.81 ? 552 TRP A CD2 1 ATOM 4394 N NE1 . TRP A 1 552 ? -15.088 -25.354 29.534 1.00 16.81 ? 552 TRP A NE1 1 ATOM 4395 C CE2 . TRP A 1 552 ? -13.988 -25.722 28.799 1.00 19.83 ? 552 TRP A CE2 1 ATOM 4396 C CE3 . TRP A 1 552 ? -12.127 -24.658 27.693 1.00 18.01 ? 552 TRP A CE3 1 ATOM 4397 C CZ2 . TRP A 1 552 ? -13.534 -27.003 28.431 1.00 19.32 ? 552 TRP A CZ2 1 ATOM 4398 C CZ3 . TRP A 1 552 ? -11.684 -25.944 27.307 1.00 18.52 ? 552 TRP A CZ3 1 ATOM 4399 C CH2 . TRP A 1 552 ? -12.399 -27.081 27.684 1.00 18.97 ? 552 TRP A CH2 1 ATOM 4400 N N . SER A 1 553 ? -14.526 -18.868 28.269 1.00 15.72 ? 553 SER A N 1 ATOM 4401 C CA . SER A 1 553 ? -14.052 -17.459 28.278 1.00 16.68 ? 553 SER A CA 1 ATOM 4402 C C . SER A 1 553 ? -14.707 -16.590 29.342 1.00 15.83 ? 553 SER A C 1 ATOM 4403 O O . SER A 1 553 ? -14.060 -15.682 29.859 1.00 14.34 ? 553 SER A O 1 ATOM 4404 C CB . SER A 1 553 ? -14.208 -16.791 26.912 1.00 16.85 ? 553 SER A CB 1 ATOM 4405 O OG . SER A 1 553 ? -15.591 -16.506 26.632 1.00 15.60 ? 553 SER A OG 1 ATOM 4406 N N . ILE A 1 554 ? -15.978 -16.851 29.665 1.00 15.54 ? 554 ILE A N 1 ATOM 4407 C CA . ILE A 1 554 ? -16.694 -15.951 30.547 1.00 14.89 ? 554 ILE A CA 1 ATOM 4408 C C . ILE A 1 554 ? -16.162 -16.040 31.970 1.00 15.08 ? 554 ILE A C 1 ATOM 4409 O O . ILE A 1 554 ? -15.857 -15.016 32.545 1.00 14.98 ? 554 ILE A O 1 ATOM 4410 C CB . ILE A 1 554 ? -18.251 -16.126 30.492 1.00 15.73 ? 554 ILE A CB 1 ATOM 4411 C CG1 . ILE A 1 554 ? -18.745 -15.665 29.119 1.00 17.66 ? 554 ILE A CG1 1 ATOM 4412 C CG2 . ILE A 1 554 ? -18.879 -15.239 31.546 1.00 15.41 ? 554 ILE A CG2 1 ATOM 4413 C CD1 . ILE A 1 554 ? -20.175 -16.177 28.748 1.00 15.65 ? 554 ILE A CD1 1 ATOM 4414 N N . PRO A 1 555 ? -16.024 -17.253 32.536 1.00 14.73 ? 555 PRO A N 1 ATOM 4415 C CA . PRO A 1 555 ? -15.367 -17.202 33.852 1.00 16.08 ? 555 PRO A CA 1 ATOM 4416 C C . PRO A 1 555 ? -13.999 -16.564 33.904 1.00 15.83 ? 555 PRO A C 1 ATOM 4417 O O . PRO A 1 555 ? -13.687 -15.928 34.922 1.00 15.18 ? 555 PRO A O 1 ATOM 4418 C CB . PRO A 1 555 ? -15.261 -18.675 34.261 1.00 16.07 ? 555 PRO A CB 1 ATOM 4419 C CG . PRO A 1 555 ? -16.431 -19.338 33.605 1.00 14.65 ? 555 PRO A CG 1 ATOM 4420 C CD . PRO A 1 555 ? -16.478 -18.626 32.225 1.00 15.18 ? 555 PRO A CD 1 ATOM 4421 N N . GLY A 1 556 ? -13.189 -16.752 32.857 1.00 16.00 ? 556 GLY A N 1 ATOM 4422 C CA . GLY A 1 556 ? -11.835 -16.153 32.787 1.00 14.40 ? 556 GLY A CA 1 ATOM 4423 C C . GLY A 1 556 ? -11.917 -14.636 32.821 1.00 15.00 ? 556 GLY A C 1 ATOM 4424 O O . GLY A 1 556 ? -11.147 -14.007 33.512 1.00 13.90 ? 556 GLY A O 1 ATOM 4425 N N . VAL A 1 557 ? -12.880 -14.053 32.085 1.00 13.43 ? 557 VAL A N 1 ATOM 4426 C CA . VAL A 1 557 ? -13.067 -12.607 32.069 1.00 13.19 ? 557 VAL A CA 1 ATOM 4427 C C . VAL A 1 557 ? -13.515 -12.101 33.452 1.00 13.07 ? 557 VAL A C 1 ATOM 4428 O O . VAL A 1 557 ? -13.029 -11.069 33.945 1.00 11.84 ? 557 VAL A O 1 ATOM 4429 C CB . VAL A 1 557 ? -14.111 -12.187 30.961 1.00 13.33 ? 557 VAL A CB 1 ATOM 4430 C CG1 . VAL A 1 557 ? -14.607 -10.782 31.166 1.00 15.52 ? 557 VAL A CG1 1 ATOM 4431 C CG2 . VAL A 1 557 ? -13.501 -12.301 29.590 1.00 13.49 ? 557 VAL A CG2 1 ATOM 4432 N N . LEU A 1 558 ? -14.479 -12.793 34.081 1.00 11.94 ? 558 LEU A N 1 ATOM 4433 C CA . LEU A 1 558 ? -14.935 -12.379 35.422 1.00 11.63 ? 558 LEU A CA 1 ATOM 4434 C C . LEU A 1 558 ? -13.835 -12.442 36.487 1.00 12.28 ? 558 LEU A C 1 ATOM 4435 O O . LEU A 1 558 ? -13.706 -11.554 37.345 1.00 11.39 ? 558 LEU A O 1 ATOM 4436 C CB . LEU A 1 558 ? -16.097 -13.291 35.852 1.00 12.47 ? 558 LEU A CB 1 ATOM 4437 C CG . LEU A 1 558 ? -17.328 -13.119 34.975 1.00 13.02 ? 558 LEU A CG 1 ATOM 4438 C CD1 . LEU A 1 558 ? -18.379 -14.155 35.346 1.00 11.98 ? 558 LEU A CD1 1 ATOM 4439 C CD2 . LEU A 1 558 ? -17.882 -11.703 35.047 1.00 17.26 ? 558 LEU A CD2 1 ATOM 4440 N N . GLU A 1 559 ? -13.035 -13.510 36.436 1.00 10.94 ? 559 GLU A N 1 ATOM 4441 C CA . GLU A 1 559 ? -11.986 -13.674 37.430 1.00 11.69 ? 559 GLU A CA 1 ATOM 4442 C C . GLU A 1 559 ? -10.953 -12.558 37.272 1.00 11.49 ? 559 GLU A C 1 ATOM 4443 O O . GLU A 1 559 ? -10.478 -12.045 38.273 1.00 12.11 ? 559 GLU A O 1 ATOM 4444 C CB . GLU A 1 559 ? -11.326 -15.053 37.260 1.00 11.81 ? 559 GLU A CB 1 ATOM 4445 C CG . GLU A 1 559 ? -12.216 -16.218 37.753 1.00 14.64 ? 559 GLU A CG 1 ATOM 4446 C CD . GLU A 1 559 ? -11.866 -17.559 37.113 1.00 20.98 ? 559 GLU A CD 1 ATOM 4447 O OE1 . GLU A 1 559 ? -10.924 -17.597 36.268 1.00 19.72 ? 559 GLU A OE1 1 ATOM 4448 O OE2 . GLU A 1 559 ? -12.588 -18.568 37.413 1.00 20.70 ? 559 GLU A OE2 1 ATOM 4449 N N . PHE A 1 560 ? -10.560 -12.208 36.044 1.00 10.44 ? 560 PHE A N 1 ATOM 4450 C CA . PHE A 1 560 ? -9.571 -11.085 35.905 1.00 11.19 ? 560 PHE A CA 1 ATOM 4451 C C . PHE A 1 560 ? -10.114 -9.757 36.346 1.00 12.29 ? 560 PHE A C 1 ATOM 4452 O O . PHE A 1 560 ? -9.372 -8.877 36.761 1.00 11.52 ? 560 PHE A O 1 ATOM 4453 C CB . PHE A 1 560 ? -8.951 -11.048 34.515 1.00 10.10 ? 560 PHE A CB 1 ATOM 4454 C CG . PHE A 1 560 ? -7.794 -11.988 34.435 1.00 13.68 ? 560 PHE A CG 1 ATOM 4455 C CD1 . PHE A 1 560 ? -7.987 -13.306 34.105 1.00 14.36 ? 560 PHE A CD1 1 ATOM 4456 C CD2 . PHE A 1 560 ? -6.533 -11.556 34.850 1.00 13.94 ? 560 PHE A CD2 1 ATOM 4457 C CE1 . PHE A 1 560 ? -6.923 -14.220 34.138 1.00 16.69 ? 560 PHE A CE1 1 ATOM 4458 C CE2 . PHE A 1 560 ? -5.431 -12.463 34.861 1.00 14.14 ? 560 PHE A CE2 1 ATOM 4459 C CZ . PHE A 1 560 ? -5.649 -13.775 34.501 1.00 13.18 ? 560 PHE A CZ 1 ATOM 4460 N N . ASN A 1 561 ? -11.431 -9.598 36.259 1.00 11.41 ? 561 ASN A N 1 ATOM 4461 C CA . ASN A 1 561 ? -12.045 -8.412 36.870 1.00 12.60 ? 561 ASN A CA 1 ATOM 4462 C C . ASN A 1 561 ? -11.891 -8.399 38.405 1.00 12.48 ? 561 ASN A C 1 ATOM 4463 O O . ASN A 1 561 ? -11.607 -7.348 39.007 1.00 13.89 ? 561 ASN A O 1 ATOM 4464 C CB . ASN A 1 561 ? -13.511 -8.272 36.417 1.00 11.79 ? 561 ASN A CB 1 ATOM 4465 C CG . ASN A 1 561 ? -13.605 -7.508 35.114 1.00 14.00 ? 561 ASN A CG 1 ATOM 4466 O OD1 . ASN A 1 561 ? -13.972 -6.323 35.109 1.00 14.73 ? 561 ASN A OD1 1 ATOM 4467 N ND2 . ASN A 1 561 ? -13.150 -8.138 34.013 1.00 15.59 ? 561 ASN A ND2 1 ATOM 4468 N N . LEU A 1 562 ? -12.038 -9.562 39.038 1.00 12.92 ? 562 LEU A N 1 ATOM 4469 C CA . LEU A 1 562 ? -11.785 -9.669 40.470 1.00 12.73 ? 562 LEU A CA 1 ATOM 4470 C C . LEU A 1 562 ? -10.345 -9.303 40.731 1.00 12.67 ? 562 LEU A C 1 ATOM 4471 O O . LEU A 1 562 ? -10.028 -8.739 41.760 1.00 12.37 ? 562 LEU A O 1 ATOM 4472 C CB . LEU A 1 562 ? -11.955 -11.096 40.962 1.00 13.80 ? 562 LEU A CB 1 ATOM 4473 C CG . LEU A 1 562 ? -13.279 -11.802 40.899 1.00 15.54 ? 562 LEU A CG 1 ATOM 4474 C CD1 . LEU A 1 562 ? -13.056 -13.114 41.674 1.00 17.37 ? 562 LEU A CD1 1 ATOM 4475 C CD2 . LEU A 1 562 ? -14.413 -10.911 41.492 1.00 14.38 ? 562 LEU A CD2 1 ATOM 4476 N N . PHE A 1 563 ? -9.465 -9.701 39.820 1.00 12.75 ? 563 PHE A N 1 ATOM 4477 C CA . PHE A 1 563 ? -8.010 -9.446 39.997 1.00 13.06 ? 563 PHE A CA 1 ATOM 4478 C C . PHE A 1 563 ? -7.578 -7.999 39.675 1.00 14.16 ? 563 PHE A C 1 ATOM 4479 O O . PHE A 1 563 ? -6.370 -7.643 39.725 1.00 13.34 ? 563 PHE A O 1 ATOM 4480 C CB . PHE A 1 563 ? -7.217 -10.457 39.109 1.00 12.20 ? 563 PHE A CB 1 ATOM 4481 C CG . PHE A 1 563 ? -7.558 -11.914 39.363 1.00 11.34 ? 563 PHE A CG 1 ATOM 4482 C CD1 . PHE A 1 563 ? -7.919 -12.370 40.646 1.00 13.53 ? 563 PHE A CD1 1 ATOM 4483 C CD2 . PHE A 1 563 ? -7.432 -12.844 38.321 1.00 13.09 ? 563 PHE A CD2 1 ATOM 4484 C CE1 . PHE A 1 563 ? -8.195 -13.701 40.862 1.00 14.22 ? 563 PHE A CE1 1 ATOM 4485 C CE2 . PHE A 1 563 ? -7.737 -14.200 38.530 1.00 16.78 ? 563 PHE A CE2 1 ATOM 4486 C CZ . PHE A 1 563 ? -8.100 -14.612 39.797 1.00 13.19 ? 563 PHE A CZ 1 ATOM 4487 N N . GLY A 1 564 ? -8.524 -7.121 39.364 1.00 12.41 ? 564 GLY A N 1 ATOM 4488 C CA . GLY A 1 564 ? -8.145 -5.759 39.005 1.00 13.14 ? 564 GLY A CA 1 ATOM 4489 C C . GLY A 1 564 ? -7.492 -5.594 37.646 1.00 13.15 ? 564 GLY A C 1 ATOM 4490 O O . GLY A 1 564 ? -6.732 -4.656 37.441 1.00 14.08 ? 564 GLY A O 1 ATOM 4491 N N . ILE A 1 565 ? -7.748 -6.527 36.734 1.00 11.41 ? 565 ILE A N 1 ATOM 4492 C CA . ILE A 1 565 ? -7.355 -6.394 35.331 1.00 12.63 ? 565 ILE A CA 1 ATOM 4493 C C . ILE A 1 565 ? -8.644 -6.425 34.502 1.00 12.61 ? 565 ILE A C 1 ATOM 4494 O O . ILE A 1 565 ? -8.944 -7.397 33.813 1.00 12.85 ? 565 ILE A O 1 ATOM 4495 C CB . ILE A 1 565 ? -6.399 -7.538 34.932 1.00 13.59 ? 565 ILE A CB 1 ATOM 4496 C CG1 . ILE A 1 565 ? -5.279 -7.615 35.981 1.00 13.30 ? 565 ILE A CG1 1 ATOM 4497 C CG2 . ILE A 1 565 ? -5.923 -7.348 33.487 1.00 14.89 ? 565 ILE A CG2 1 ATOM 4498 C CD1 . ILE A 1 565 ? -4.179 -8.767 35.771 1.00 15.59 ? 565 ILE A CD1 1 ATOM 4499 N N . PRO A 1 566 ? -9.433 -5.337 34.593 1.00 12.99 ? 566 PRO A N 1 ATOM 4500 C CA . PRO A 1 566 ? -10.742 -5.395 33.962 1.00 13.11 ? 566 PRO A CA 1 ATOM 4501 C C . PRO A 1 566 ? -10.751 -5.431 32.438 1.00 12.66 ? 566 PRO A C 1 ATOM 4502 O O . PRO A 1 566 ? -11.679 -5.961 31.873 1.00 11.82 ? 566 PRO A O 1 ATOM 4503 C CB . PRO A 1 566 ? -11.458 -4.151 34.491 1.00 12.24 ? 566 PRO A CB 1 ATOM 4504 C CG . PRO A 1 566 ? -10.342 -3.169 34.828 1.00 12.78 ? 566 PRO A CG 1 ATOM 4505 C CD . PRO A 1 566 ? -9.182 -4.064 35.288 1.00 13.10 ? 566 PRO A CD 1 ATOM 4506 N N . MET A 1 567 ? -9.763 -4.832 31.789 1.00 12.19 ? 567 MET A N 1 ATOM 4507 C CA . MET A 1 567 ? -9.627 -4.933 30.355 1.00 13.88 ? 567 MET A CA 1 ATOM 4508 C C . MET A 1 567 ? -9.028 -6.301 30.029 1.00 12.96 ? 567 MET A C 1 ATOM 4509 O O . MET A 1 567 ? -7.794 -6.465 30.021 1.00 14.35 ? 567 MET A O 1 ATOM 4510 C CB . MET A 1 567 ? -8.750 -3.785 29.814 1.00 12.81 ? 567 MET A CB 1 ATOM 4511 C CG . MET A 1 567 ? -8.839 -3.737 28.284 1.00 16.71 ? 567 MET A CG 1 ATOM 4512 S SD . MET A 1 567 ? -8.249 -2.207 27.600 1.00 20.26 ? 567 MET A SD 1 ATOM 4513 C CE . MET A 1 567 ? -9.825 -1.353 27.520 1.00 19.00 ? 567 MET A CE 1 ATOM 4514 N N . VAL A 1 568 ? -9.909 -7.288 29.823 1.00 10.79 ? 568 VAL A N 1 ATOM 4515 C CA . VAL A 1 568 ? -9.536 -8.676 29.630 1.00 12.08 ? 568 VAL A CA 1 ATOM 4516 C C . VAL A 1 568 ? -10.514 -9.260 28.614 1.00 13.16 ? 568 VAL A C 1 ATOM 4517 O O . VAL A 1 568 ? -11.680 -8.849 28.540 1.00 12.24 ? 568 VAL A O 1 ATOM 4518 C CB . VAL A 1 568 ? -9.495 -9.495 30.981 1.00 10.78 ? 568 VAL A CB 1 ATOM 4519 C CG1 . VAL A 1 568 ? -10.880 -9.444 31.706 1.00 9.91 ? 568 VAL A CG1 1 ATOM 4520 C CG2 . VAL A 1 568 ? -8.984 -10.970 30.779 1.00 11.58 ? 568 VAL A CG2 1 ATOM 4521 N N . GLY A 1 569 ? -10.028 -10.219 27.842 1.00 13.61 ? 569 GLY A N 1 ATOM 4522 C CA . GLY A 1 569 ? -10.810 -10.837 26.790 1.00 14.94 ? 569 GLY A CA 1 ATOM 4523 C C . GLY A 1 569 ? -10.011 -12.005 26.243 1.00 15.04 ? 569 GLY A C 1 ATOM 4524 O O . GLY A 1 569 ? -8.783 -12.045 26.438 1.00 16.46 ? 569 GLY A O 1 ATOM 4525 N N . PRO A 1 570 ? -10.678 -12.956 25.586 1.00 15.49 ? 570 PRO A N 1 ATOM 4526 C CA . PRO A 1 570 ? -9.941 -14.001 24.888 1.00 15.66 ? 570 PRO A CA 1 ATOM 4527 C C . PRO A 1 570 ? -9.622 -13.555 23.435 1.00 16.42 ? 570 PRO A C 1 ATOM 4528 O O . PRO A 1 570 ? -10.021 -12.446 22.989 1.00 16.61 ? 570 PRO A O 1 ATOM 4529 C CB . PRO A 1 570 ? -10.950 -15.152 24.860 1.00 15.76 ? 570 PRO A CB 1 ATOM 4530 C CG . PRO A 1 570 ? -12.306 -14.415 24.644 1.00 15.79 ? 570 PRO A CG 1 ATOM 4531 C CD . PRO A 1 570 ? -12.148 -13.117 25.438 1.00 15.72 ? 570 PRO A CD 1 ATOM 4532 N N . ASP A 1 571 ? -9.002 -14.449 22.671 1.00 16.29 ? 571 ASP A N 1 ATOM 4533 C CA . ASP A 1 571 ? -8.920 -14.248 21.211 1.00 15.67 ? 571 ASP A CA 1 ATOM 4534 C C . ASP A 1 571 ? -10.287 -14.619 20.616 1.00 16.22 ? 571 ASP A C 1 ATOM 4535 O O . ASP A 1 571 ? -10.633 -15.787 20.555 1.00 16.51 ? 571 ASP A O 1 ATOM 4536 C CB . ASP A 1 571 ? -7.873 -15.151 20.621 1.00 14.90 ? 571 ASP A CB 1 ATOM 4537 C CG . ASP A 1 571 ? -6.455 -14.719 20.978 1.00 15.68 ? 571 ASP A CG 1 ATOM 4538 O OD1 . ASP A 1 571 ? -6.255 -13.543 21.348 1.00 18.71 ? 571 ASP A OD1 1 ATOM 4539 O OD2 . ASP A 1 571 ? -5.539 -15.558 20.850 1.00 19.16 ? 571 ASP A OD2 1 ATOM 4540 N N . ILE A 1 572 ? -11.053 -13.627 20.184 1.00 16.74 ? 572 ILE A N 1 ATOM 4541 C CA . ILE A 1 572 ? -12.403 -13.897 19.701 1.00 16.05 ? 572 ILE A CA 1 ATOM 4542 C C . ILE A 1 572 ? -12.286 -14.782 18.439 1.00 16.76 ? 572 ILE A C 1 ATOM 4543 O O . ILE A 1 572 ? -11.432 -14.526 17.581 1.00 17.72 ? 572 ILE A O 1 ATOM 4544 C CB . ILE A 1 572 ? -13.166 -12.602 19.361 1.00 16.22 ? 572 ILE A CB 1 ATOM 4545 C CG1 . ILE A 1 572 ? -13.435 -11.786 20.644 1.00 15.86 ? 572 ILE A CG1 1 ATOM 4546 C CG2 . ILE A 1 572 ? -14.474 -12.929 18.559 1.00 16.06 ? 572 ILE A CG2 1 ATOM 4547 C CD1 . ILE A 1 572 ? -13.923 -10.358 20.383 1.00 16.35 ? 572 ILE A CD1 1 ATOM 4548 N N . CYS A 1 573 ? -13.148 -15.802 18.355 1.00 16.67 ? 573 CYS A N 1 ATOM 4549 C CA . CYS A 1 573 ? -13.212 -16.798 17.260 1.00 16.80 ? 573 CYS A CA 1 ATOM 4550 C C . CYS A 1 573 ? -12.210 -17.925 17.408 1.00 17.51 ? 573 CYS A C 1 ATOM 4551 O O . CYS A 1 573 ? -12.373 -18.984 16.798 1.00 18.70 ? 573 CYS A O 1 ATOM 4552 C CB . CYS A 1 573 ? -13.186 -16.178 15.851 1.00 17.55 ? 573 CYS A CB 1 ATOM 4553 S SG . CYS A 1 573 ? -14.692 -15.168 15.629 1.00 19.05 ? 573 CYS A SG 1 ATOM 4554 N N . GLY A 1 574 ? -11.214 -17.715 18.251 1.00 16.46 ? 574 GLY A N 1 ATOM 4555 C CA . GLY A 1 574 ? -10.311 -18.787 18.652 1.00 17.37 ? 574 GLY A CA 1 ATOM 4556 C C . GLY A 1 574 ? -8.982 -18.652 17.936 1.00 17.76 ? 574 GLY A C 1 ATOM 4557 O O . GLY A 1 574 ? -8.966 -18.566 16.728 1.00 18.54 ? 574 GLY A O 1 ATOM 4558 N N . PHE A 1 575 ? -7.890 -18.700 18.695 1.00 17.08 ? 575 PHE A N 1 ATOM 4559 C CA . PHE A 1 575 ? -6.530 -18.567 18.148 1.00 17.86 ? 575 PHE A CA 1 ATOM 4560 C C . PHE A 1 575 ? -6.206 -19.812 17.304 1.00 17.77 ? 575 PHE A C 1 ATOM 4561 O O . PHE A 1 575 ? -6.131 -19.702 16.081 1.00 18.21 ? 575 PHE A O 1 ATOM 4562 C CB . PHE A 1 575 ? -5.547 -18.360 19.293 1.00 15.93 ? 575 PHE A CB 1 ATOM 4563 C CG . PHE A 1 575 ? -4.088 -18.347 18.891 1.00 17.54 ? 575 PHE A CG 1 ATOM 4564 C CD1 . PHE A 1 575 ? -3.500 -17.197 18.329 1.00 14.52 ? 575 PHE A CD1 1 ATOM 4565 C CD2 . PHE A 1 575 ? -3.299 -19.457 19.135 1.00 17.87 ? 575 PHE A CD2 1 ATOM 4566 C CE1 . PHE A 1 575 ? -2.122 -17.178 18.001 1.00 19.24 ? 575 PHE A CE1 1 ATOM 4567 C CE2 . PHE A 1 575 ? -1.916 -19.458 18.786 1.00 17.75 ? 575 PHE A CE2 1 ATOM 4568 C CZ . PHE A 1 575 ? -1.332 -18.307 18.251 1.00 16.83 ? 575 PHE A CZ 1 ATOM 4569 N N . ALA A 1 576 ? -6.059 -20.986 17.933 1.00 17.64 ? 576 ALA A N 1 ATOM 4570 C CA . ALA A 1 576 ? -5.751 -22.236 17.201 1.00 18.71 ? 576 ALA A CA 1 ATOM 4571 C C . ALA A 1 576 ? -6.969 -22.788 16.413 1.00 18.71 ? 576 ALA A C 1 ATOM 4572 O O . ALA A 1 576 ? -8.074 -22.749 16.904 1.00 20.18 ? 576 ALA A O 1 ATOM 4573 C CB . ALA A 1 576 ? -5.231 -23.316 18.176 1.00 17.68 ? 576 ALA A CB 1 ATOM 4574 N N . LEU A 1 577 ? -6.727 -23.284 15.190 1.00 18.92 ? 577 LEU A N 1 ATOM 4575 C CA . LEU A 1 577 ? -7.706 -23.955 14.330 1.00 19.83 ? 577 LEU A CA 1 ATOM 4576 C C . LEU A 1 577 ? -8.504 -22.985 13.455 1.00 20.01 ? 577 LEU A C 1 ATOM 4577 O O . LEU A 1 577 ? -8.655 -21.804 13.790 1.00 18.46 ? 577 LEU A O 1 ATOM 4578 C CB . LEU A 1 577 ? -8.665 -24.875 15.135 1.00 19.47 ? 577 LEU A CB 1 ATOM 4579 C CG . LEU A 1 577 ? -8.230 -26.283 15.545 1.00 22.90 ? 577 LEU A CG 1 ATOM 4580 C CD1 . LEU A 1 577 ? -6.730 -26.456 15.765 1.00 24.96 ? 577 LEU A CD1 1 ATOM 4581 C CD2 . LEU A 1 577 ? -9.063 -26.794 16.691 1.00 20.89 ? 577 LEU A CD2 1 ATOM 4582 N N . ASP A 1 578 ? -9.002 -23.516 12.334 1.00 20.17 ? 578 ASP A N 1 ATOM 4583 C CA . ASP A 1 578 ? -9.988 -22.840 11.489 1.00 21.27 ? 578 ASP A CA 1 ATOM 4584 C C . ASP A 1 578 ? -11.300 -22.727 12.275 1.00 21.26 ? 578 ASP A C 1 ATOM 4585 O O . ASP A 1 578 ? -11.757 -23.699 12.876 1.00 22.11 ? 578 ASP A O 1 ATOM 4586 C CB . ASP A 1 578 ? -10.267 -23.670 10.233 1.00 22.34 ? 578 ASP A CB 1 ATOM 4587 C CG . ASP A 1 578 ? -9.060 -23.780 9.284 1.00 23.79 ? 578 ASP A CG 1 ATOM 4588 O OD1 . ASP A 1 578 ? -7.976 -23.180 9.506 1.00 24.37 ? 578 ASP A OD1 1 ATOM 4589 O OD2 . ASP A 1 578 ? -9.209 -24.517 8.299 1.00 26.43 ? 578 ASP A OD2 1 ATOM 4590 N N . THR A 1 579 ? -11.903 -21.544 12.266 1.00 21.03 ? 579 THR A N 1 ATOM 4591 C CA . THR A 1 579 ? -13.103 -21.323 13.034 1.00 21.18 ? 579 THR A CA 1 ATOM 4592 C C . THR A 1 579 ? -14.324 -21.606 12.154 1.00 21.75 ? 579 THR A C 1 ATOM 4593 O O . THR A 1 579 ? -14.372 -21.131 11.022 1.00 21.31 ? 579 THR A O 1 ATOM 4594 C CB . THR A 1 579 ? -13.127 -19.907 13.665 1.00 20.98 ? 579 THR A CB 1 ATOM 4595 O OG1 . THR A 1 579 ? -14.121 -19.844 14.683 1.00 21.76 ? 579 THR A OG1 1 ATOM 4596 C CG2 . THR A 1 579 ? -13.380 -18.782 12.629 1.00 20.40 ? 579 THR A CG2 1 ATOM 4597 N N . PRO A 1 580 ? -15.281 -22.400 12.667 1.00 21.85 ? 580 PRO A N 1 ATOM 4598 C CA . PRO A 1 580 ? -16.572 -22.578 11.979 1.00 22.04 ? 580 PRO A CA 1 ATOM 4599 C C . PRO A 1 580 ? -17.322 -21.237 11.913 1.00 21.58 ? 580 PRO A C 1 ATOM 4600 O O . PRO A 1 580 ? -17.253 -20.449 12.863 1.00 20.85 ? 580 PRO A O 1 ATOM 4601 C CB . PRO A 1 580 ? -17.343 -23.537 12.896 1.00 22.06 ? 580 PRO A CB 1 ATOM 4602 C CG . PRO A 1 580 ? -16.362 -24.096 13.847 1.00 23.88 ? 580 PRO A CG 1 ATOM 4603 C CD . PRO A 1 580 ? -15.215 -23.136 13.946 1.00 21.99 ? 580 PRO A CD 1 ATOM 4604 N N . GLU A 1 581 ? -18.027 -20.964 10.814 1.00 20.60 ? 581 GLU A N 1 ATOM 4605 C CA . GLU A 1 581 ? -18.841 -19.741 10.730 1.00 20.69 ? 581 GLU A CA 1 ATOM 4606 C C . GLU A 1 581 ? -19.778 -19.515 11.926 1.00 19.22 ? 581 GLU A C 1 ATOM 4607 O O . GLU A 1 581 ? -19.954 -18.388 12.378 1.00 18.60 ? 581 GLU A O 1 ATOM 4608 C CB . GLU A 1 581 ? -19.659 -19.724 9.436 1.00 20.59 ? 581 GLU A CB 1 ATOM 4609 C CG . GLU A 1 581 ? -20.376 -18.415 9.158 1.00 23.10 ? 581 GLU A CG 1 ATOM 4610 C CD . GLU A 1 581 ? -21.730 -18.290 9.840 1.00 24.64 ? 581 GLU A CD 1 ATOM 4611 O OE1 . GLU A 1 581 ? -22.287 -19.287 10.377 1.00 24.20 ? 581 GLU A OE1 1 ATOM 4612 O OE2 . GLU A 1 581 ? -22.264 -17.167 9.812 1.00 29.27 ? 581 GLU A OE2 1 ATOM 4613 N N . GLU A 1 582 ? -20.439 -20.566 12.381 1.00 18.89 ? 582 GLU A N 1 ATOM 4614 C CA . GLU A 1 582 ? -21.453 -20.401 13.403 1.00 19.86 ? 582 GLU A CA 1 ATOM 4615 C C . GLU A 1 582 ? -20.798 -20.026 14.749 1.00 18.51 ? 582 GLU A C 1 ATOM 4616 O O . GLU A 1 582 ? -21.298 -19.166 15.486 1.00 17.75 ? 582 GLU A O 1 ATOM 4617 C CB . GLU A 1 582 ? -22.306 -21.661 13.543 1.00 19.40 ? 582 GLU A CB 1 ATOM 4618 C CG . GLU A 1 582 ? -23.420 -21.490 14.565 1.00 21.98 ? 582 GLU A CG 1 ATOM 4619 C CD . GLU A 1 582 ? -24.016 -22.792 15.032 1.00 25.88 ? 582 GLU A CD 1 ATOM 4620 O OE1 . GLU A 1 582 ? -23.727 -23.867 14.433 1.00 29.89 ? 582 GLU A OE1 1 ATOM 4621 O OE2 . GLU A 1 582 ? -24.796 -22.746 16.009 1.00 28.43 ? 582 GLU A OE2 1 ATOM 4622 N N . LEU A 1 583 ? -19.676 -20.674 15.040 1.00 17.36 ? 583 LEU A N 1 ATOM 4623 C CA . LEU A 1 583 ? -18.937 -20.407 16.266 1.00 16.97 ? 583 LEU A CA 1 ATOM 4624 C C . LEU A 1 583 ? -18.392 -18.971 16.217 1.00 16.95 ? 583 LEU A C 1 ATOM 4625 O O . LEU A 1 583 ? -18.597 -18.227 17.146 1.00 17.05 ? 583 LEU A O 1 ATOM 4626 C CB . LEU A 1 583 ? -17.796 -21.425 16.472 1.00 16.12 ? 583 LEU A CB 1 ATOM 4627 C CG . LEU A 1 583 ? -16.801 -21.045 17.589 1.00 16.79 ? 583 LEU A CG 1 ATOM 4628 C CD1 . LEU A 1 583 ? -17.462 -21.091 18.964 1.00 16.51 ? 583 LEU A CD1 1 ATOM 4629 C CD2 . LEU A 1 583 ? -15.588 -21.967 17.545 1.00 15.92 ? 583 LEU A CD2 1 ATOM 4630 N N . CYS A 1 584 ? -17.767 -18.573 15.110 1.00 18.23 ? 584 CYS A N 1 ATOM 4631 C CA . CYS A 1 584 ? -17.251 -17.206 14.982 1.00 17.95 ? 584 CYS A CA 1 ATOM 4632 C C . CYS A 1 584 ? -18.341 -16.133 15.070 1.00 17.95 ? 584 CYS A C 1 ATOM 4633 O O . CYS A 1 584 ? -18.139 -15.114 15.712 1.00 17.98 ? 584 CYS A O 1 ATOM 4634 C CB . CYS A 1 584 ? -16.417 -17.052 13.724 1.00 18.88 ? 584 CYS A CB 1 ATOM 4635 S SG . CYS A 1 584 ? -15.318 -15.572 13.689 1.00 20.02 ? 584 CYS A SG 1 ATOM 4636 N N . ARG A 1 585 ? -19.506 -16.388 14.465 1.00 16.60 ? 585 ARG A N 1 ATOM 4637 C CA . ARG A 1 585 ? -20.638 -15.482 14.567 1.00 16.07 ? 585 ARG A CA 1 ATOM 4638 C C . ARG A 1 585 ? -21.108 -15.320 16.014 1.00 15.77 ? 585 ARG A C 1 ATOM 4639 O O . ARG A 1 585 ? -21.269 -14.188 16.478 1.00 15.17 ? 585 ARG A O 1 ATOM 4640 C CB . ARG A 1 585 ? -21.798 -15.982 13.684 1.00 15.60 ? 585 ARG A CB 1 ATOM 4641 C CG . ARG A 1 585 ? -23.130 -15.186 13.837 1.00 16.55 ? 585 ARG A CG 1 ATOM 4642 C CD . ARG A 1 585 ? -24.022 -15.403 12.557 1.00 16.25 ? 585 ARG A CD 1 ATOM 4643 N NE . ARG A 1 585 ? -24.026 -16.780 12.076 1.00 17.66 ? 585 ARG A NE 1 ATOM 4644 C CZ . ARG A 1 585 ? -24.726 -17.783 12.624 1.00 19.39 ? 585 ARG A CZ 1 ATOM 4645 N NH1 . ARG A 1 585 ? -25.489 -17.588 13.686 1.00 25.74 ? 585 ARG A NH1 1 ATOM 4646 N NH2 . ARG A 1 585 ? -24.642 -19.002 12.134 1.00 17.50 ? 585 ARG A NH2 1 ATOM 4647 N N . ARG A 1 586 ? -21.311 -16.430 16.731 1.00 15.30 ? 586 ARG A N 1 ATOM 4648 C CA . ARG A 1 586 ? -21.688 -16.343 18.152 1.00 15.18 ? 586 ARG A CA 1 ATOM 4649 C C . ARG A 1 586 ? -20.581 -15.694 19.000 1.00 14.82 ? 586 ARG A C 1 ATOM 4650 O O . ARG A 1 586 ? -20.859 -14.967 19.960 1.00 15.39 ? 586 ARG A O 1 ATOM 4651 C CB . ARG A 1 586 ? -22.064 -17.713 18.746 1.00 14.35 ? 586 ARG A CB 1 ATOM 4652 C CG . ARG A 1 586 ? -23.288 -18.364 18.114 1.00 16.35 ? 586 ARG A CG 1 ATOM 4653 C CD . ARG A 1 586 ? -24.401 -17.377 18.011 1.00 15.73 ? 586 ARG A CD 1 ATOM 4654 N NE . ARG A 1 586 ? -25.691 -18.050 17.883 1.00 17.65 ? 586 ARG A NE 1 ATOM 4655 C CZ . ARG A 1 586 ? -26.864 -17.424 17.941 1.00 17.33 ? 586 ARG A CZ 1 ATOM 4656 N NH1 . ARG A 1 586 ? -26.907 -16.121 18.088 1.00 15.14 ? 586 ARG A NH1 1 ATOM 4657 N NH2 . ARG A 1 586 ? -28.005 -18.121 17.830 1.00 16.61 ? 586 ARG A NH2 1 ATOM 4658 N N . TRP A 1 587 ? -19.326 -15.976 18.664 1.00 15.04 ? 587 TRP A N 1 ATOM 4659 C CA . TRP A 1 587 ? -18.227 -15.456 19.464 1.00 14.71 ? 587 TRP A CA 1 ATOM 4660 C C . TRP A 1 587 ? -18.067 -13.950 19.220 1.00 14.71 ? 587 TRP A C 1 ATOM 4661 O O . TRP A 1 587 ? -17.752 -13.212 20.139 1.00 15.05 ? 587 TRP A O 1 ATOM 4662 C CB . TRP A 1 587 ? -16.906 -16.167 19.114 1.00 14.30 ? 587 TRP A CB 1 ATOM 4663 C CG . TRP A 1 587 ? -15.984 -16.294 20.271 1.00 14.71 ? 587 TRP A CG 1 ATOM 4664 C CD1 . TRP A 1 587 ? -15.824 -15.411 21.309 1.00 14.24 ? 587 TRP A CD1 1 ATOM 4665 C CD2 . TRP A 1 587 ? -15.066 -17.372 20.511 1.00 14.78 ? 587 TRP A CD2 1 ATOM 4666 N NE1 . TRP A 1 587 ? -14.874 -15.877 22.192 1.00 13.36 ? 587 TRP A NE1 1 ATOM 4667 C CE2 . TRP A 1 587 ? -14.389 -17.080 21.718 1.00 14.25 ? 587 TRP A CE2 1 ATOM 4668 C CE3 . TRP A 1 587 ? -14.774 -18.573 19.831 1.00 14.48 ? 587 TRP A CE3 1 ATOM 4669 C CZ2 . TRP A 1 587 ? -13.409 -17.945 22.262 1.00 13.88 ? 587 TRP A CZ2 1 ATOM 4670 C CZ3 . TRP A 1 587 ? -13.806 -19.435 20.377 1.00 15.36 ? 587 TRP A CZ3 1 ATOM 4671 C CH2 . TRP A 1 587 ? -13.136 -19.108 21.574 1.00 13.34 ? 587 TRP A CH2 1 ATOM 4672 N N . MET A 1 588 ? -18.290 -13.492 17.989 1.00 14.62 ? 588 MET A N 1 ATOM 4673 C CA . MET A 1 588 ? -18.277 -12.046 17.703 1.00 14.67 ? 588 MET A CA 1 ATOM 4674 C C . MET A 1 588 ? -19.414 -11.302 18.386 1.00 14.78 ? 588 MET A C 1 ATOM 4675 O O . MET A 1 588 ? -19.245 -10.179 18.823 1.00 14.29 ? 588 MET A O 1 ATOM 4676 C CB . MET A 1 588 ? -18.302 -11.756 16.204 1.00 15.84 ? 588 MET A CB 1 ATOM 4677 C CG . MET A 1 588 ? -16.967 -11.942 15.497 1.00 15.99 ? 588 MET A CG 1 ATOM 4678 S SD . MET A 1 588 ? -15.650 -10.800 16.021 1.00 18.24 ? 588 MET A SD 1 ATOM 4679 C CE . MET A 1 588 ? -16.315 -9.183 15.611 1.00 19.93 ? 588 MET A CE 1 ATOM 4680 N N . GLN A 1 589 ? -20.575 -11.942 18.498 1.00 13.87 ? 589 GLN A N 1 ATOM 4681 C CA . GLN A 1 589 ? -21.694 -11.332 19.212 1.00 14.61 ? 589 GLN A CA 1 ATOM 4682 C C . GLN A 1 589 ? -21.357 -11.141 20.669 1.00 14.36 ? 589 GLN A C 1 ATOM 4683 O O . GLN A 1 589 ? -21.562 -10.050 21.203 1.00 15.99 ? 589 GLN A O 1 ATOM 4684 C CB . GLN A 1 589 ? -22.941 -12.227 19.106 1.00 14.37 ? 589 GLN A CB 1 ATOM 4685 C CG . GLN A 1 589 ? -23.491 -12.184 17.676 1.00 17.07 ? 589 GLN A CG 1 ATOM 4686 C CD . GLN A 1 589 ? -24.504 -13.278 17.347 1.00 17.94 ? 589 GLN A CD 1 ATOM 4687 O OE1 . GLN A 1 589 ? -24.752 -14.200 18.130 1.00 17.69 ? 589 GLN A OE1 1 ATOM 4688 N NE2 . GLN A 1 589 ? -25.083 -13.172 16.164 1.00 21.19 ? 589 GLN A NE2 1 ATOM 4689 N N . LEU A 1 590 ? -20.821 -12.194 21.306 1.00 12.94 ? 590 LEU A N 1 ATOM 4690 C CA . LEU A 1 590 ? -20.438 -12.104 22.707 1.00 13.15 ? 590 LEU A CA 1 ATOM 4691 C C . LEU A 1 590 ? -19.219 -11.189 22.824 1.00 13.49 ? 590 LEU A C 1 ATOM 4692 O O . LEU A 1 590 ? -19.140 -10.390 23.761 1.00 13.10 ? 590 LEU A O 1 ATOM 4693 C CB . LEU A 1 590 ? -20.092 -13.478 23.286 1.00 12.95 ? 590 LEU A CB 1 ATOM 4694 C CG . LEU A 1 590 ? -19.431 -13.448 24.697 1.00 12.40 ? 590 LEU A CG 1 ATOM 4695 C CD1 . LEU A 1 590 ? -20.353 -12.793 25.704 1.00 14.08 ? 590 LEU A CD1 1 ATOM 4696 C CD2 . LEU A 1 590 ? -19.150 -14.883 25.090 1.00 17.08 ? 590 LEU A CD2 1 ATOM 4697 N N . GLY A 1 591 ? -18.267 -11.369 21.899 1.00 14.55 ? 591 GLY A N 1 ATOM 4698 C CA . GLY A 1 591 ? -16.993 -10.627 21.895 1.00 14.87 ? 591 GLY A CA 1 ATOM 4699 C C . GLY A 1 591 ? -17.148 -9.109 21.783 1.00 14.28 ? 591 GLY A C 1 ATOM 4700 O O . GLY A 1 591 ? -16.300 -8.336 22.254 1.00 13.68 ? 591 GLY A O 1 ATOM 4701 N N . ALA A 1 592 ? -18.222 -8.647 21.141 1.00 12.98 ? 592 ALA A N 1 ATOM 4702 C CA . ALA A 1 592 ? -18.570 -7.235 21.211 1.00 13.51 ? 592 ALA A CA 1 ATOM 4703 C C . ALA A 1 592 ? -18.728 -6.683 22.638 1.00 13.31 ? 592 ALA A C 1 ATOM 4704 O O . ALA A 1 592 ? -18.713 -5.450 22.847 1.00 13.89 ? 592 ALA A O 1 ATOM 4705 C CB . ALA A 1 592 ? -19.833 -6.926 20.355 1.00 13.24 ? 592 ALA A CB 1 ATOM 4706 N N . PHE A 1 593 ? -18.919 -7.571 23.608 1.00 13.00 ? 593 PHE A N 1 ATOM 4707 C CA . PHE A 1 593 ? -19.121 -7.156 25.012 1.00 13.79 ? 593 PHE A CA 1 ATOM 4708 C C . PHE A 1 593 ? -18.033 -7.597 25.970 1.00 14.08 ? 593 PHE A C 1 ATOM 4709 O O . PHE A 1 593 ? -18.203 -7.483 27.186 1.00 14.63 ? 593 PHE A O 1 ATOM 4710 C CB . PHE A 1 593 ? -20.542 -7.581 25.464 1.00 13.80 ? 593 PHE A CB 1 ATOM 4711 C CG . PHE A 1 593 ? -21.570 -6.982 24.569 1.00 14.86 ? 593 PHE A CG 1 ATOM 4712 C CD1 . PHE A 1 593 ? -21.955 -5.647 24.776 1.00 14.52 ? 593 PHE A CD1 1 ATOM 4713 C CD2 . PHE A 1 593 ? -22.004 -7.657 23.422 1.00 16.44 ? 593 PHE A CD2 1 ATOM 4714 C CE1 . PHE A 1 593 ? -22.791 -5.003 23.898 1.00 14.24 ? 593 PHE A CE1 1 ATOM 4715 C CE2 . PHE A 1 593 ? -22.940 -7.019 22.534 1.00 14.50 ? 593 PHE A CE2 1 ATOM 4716 C CZ . PHE A 1 593 ? -23.299 -5.702 22.781 1.00 13.76 ? 593 PHE A CZ 1 ATOM 4717 N N . TYR A 1 594 ? -16.904 -8.082 25.442 1.00 13.08 ? 594 TYR A N 1 ATOM 4718 C CA . TYR A 1 594 ? -15.787 -8.377 26.346 1.00 13.12 ? 594 TYR A CA 1 ATOM 4719 C C . TYR A 1 594 ? -15.131 -7.028 26.621 1.00 14.30 ? 594 TYR A C 1 ATOM 4720 O O . TYR A 1 594 ? -15.082 -6.211 25.715 1.00 15.03 ? 594 TYR A O 1 ATOM 4721 C CB . TYR A 1 594 ? -14.743 -9.250 25.670 1.00 13.12 ? 594 TYR A CB 1 ATOM 4722 C CG . TYR A 1 594 ? -15.079 -10.700 25.480 1.00 13.20 ? 594 TYR A CG 1 ATOM 4723 C CD1 . TYR A 1 594 ? -15.612 -11.482 26.505 1.00 16.21 ? 594 TYR A CD1 1 ATOM 4724 C CD2 . TYR A 1 594 ? -14.754 -11.310 24.278 1.00 13.98 ? 594 TYR A CD2 1 ATOM 4725 C CE1 . TYR A 1 594 ? -15.869 -12.865 26.291 1.00 13.82 ? 594 TYR A CE1 1 ATOM 4726 C CE2 . TYR A 1 594 ? -14.986 -12.629 24.058 1.00 13.55 ? 594 TYR A CE2 1 ATOM 4727 C CZ . TYR A 1 594 ? -15.533 -13.404 25.056 1.00 13.34 ? 594 TYR A CZ 1 ATOM 4728 O OH . TYR A 1 594 ? -15.728 -14.719 24.761 1.00 15.39 ? 594 TYR A OH 1 ATOM 4729 N N . PRO A 1 595 ? -14.686 -6.772 27.865 1.00 14.79 ? 595 PRO A N 1 ATOM 4730 C CA . PRO A 1 595 ? -14.107 -5.472 28.127 1.00 15.11 ? 595 PRO A CA 1 ATOM 4731 C C . PRO A 1 595 ? -12.857 -5.185 27.241 1.00 15.96 ? 595 PRO A C 1 ATOM 4732 O O . PRO A 1 595 ? -12.675 -4.058 26.816 1.00 17.53 ? 595 PRO A O 1 ATOM 4733 C CB . PRO A 1 595 ? -13.779 -5.497 29.637 1.00 15.27 ? 595 PRO A CB 1 ATOM 4734 C CG . PRO A 1 595 ? -14.235 -6.804 30.174 1.00 15.65 ? 595 PRO A CG 1 ATOM 4735 C CD . PRO A 1 595 ? -14.722 -7.667 29.040 1.00 14.52 ? 595 PRO A CD 1 ATOM 4736 N N . PHE A 1 596 ? -12.032 -6.196 26.973 1.00 15.79 ? 596 PHE A N 1 ATOM 4737 C CA . PHE A 1 596 ? -11.018 -6.154 25.883 1.00 15.44 ? 596 PHE A CA 1 ATOM 4738 C C . PHE A 1 596 ? -11.559 -7.019 24.739 1.00 15.72 ? 596 PHE A C 1 ATOM 4739 O O . PHE A 1 596 ? -11.689 -8.233 24.889 1.00 15.52 ? 596 PHE A O 1 ATOM 4740 C CB . PHE A 1 596 ? -9.664 -6.749 26.342 1.00 14.58 ? 596 PHE A CB 1 ATOM 4741 C CG . PHE A 1 596 ? -8.630 -6.857 25.229 1.00 14.50 ? 596 PHE A CG 1 ATOM 4742 C CD1 . PHE A 1 596 ? -8.209 -5.708 24.552 1.00 17.10 ? 596 PHE A CD1 1 ATOM 4743 C CD2 . PHE A 1 596 ? -8.058 -8.086 24.881 1.00 15.78 ? 596 PHE A CD2 1 ATOM 4744 C CE1 . PHE A 1 596 ? -7.279 -5.782 23.539 1.00 14.03 ? 596 PHE A CE1 1 ATOM 4745 C CE2 . PHE A 1 596 ? -7.097 -8.171 23.843 1.00 14.84 ? 596 PHE A CE2 1 ATOM 4746 C CZ . PHE A 1 596 ? -6.700 -7.005 23.197 1.00 13.88 ? 596 PHE A CZ 1 ATOM 4747 N N . SER A 1 597 ? -11.877 -6.379 23.607 1.00 15.48 ? 597 SER A N 1 ATOM 4748 C CA . SER A 1 597 ? -12.496 -7.010 22.436 1.00 15.35 ? 597 SER A CA 1 ATOM 4749 C C . SER A 1 597 ? -11.519 -7.115 21.252 1.00 15.29 ? 597 SER A C 1 ATOM 4750 O O . SER A 1 597 ? -11.262 -6.109 20.562 1.00 15.90 ? 597 SER A O 1 ATOM 4751 C CB . SER A 1 597 ? -13.723 -6.173 21.999 1.00 14.87 ? 597 SER A CB 1 ATOM 4752 O OG . SER A 1 597 ? -14.390 -6.807 20.926 1.00 16.33 ? 597 SER A OG 1 ATOM 4753 N N . ARG A 1 598 ? -10.943 -8.302 21.049 1.00 15.42 ? 598 ARG A N 1 ATOM 4754 C CA . ARG A 1 598 ? -9.954 -8.527 19.995 1.00 14.63 ? 598 ARG A CA 1 ATOM 4755 C C . ARG A 1 598 ? -10.193 -9.871 19.312 1.00 14.24 ? 598 ARG A C 1 ATOM 4756 O O . ARG A 1 598 ? -10.300 -10.911 19.973 1.00 14.47 ? 598 ARG A O 1 ATOM 4757 C CB . ARG A 1 598 ? -8.492 -8.477 20.530 1.00 15.38 ? 598 ARG A CB 1 ATOM 4758 C CG . ARG A 1 598 ? -7.452 -8.721 19.451 1.00 14.88 ? 598 ARG A CG 1 ATOM 4759 C CD . ARG A 1 598 ? -6.018 -8.573 20.004 1.00 15.33 ? 598 ARG A CD 1 ATOM 4760 N NE . ARG A 1 598 ? -5.628 -9.775 20.714 1.00 17.45 ? 598 ARG A NE 1 ATOM 4761 C CZ . ARG A 1 598 ? -4.371 -10.151 20.863 1.00 18.04 ? 598 ARG A CZ 1 ATOM 4762 N NH1 . ARG A 1 598 ? -3.403 -9.381 20.378 1.00 17.89 ? 598 ARG A NH1 1 ATOM 4763 N NH2 . ARG A 1 598 ? -4.098 -11.297 21.465 1.00 17.96 ? 598 ARG A NH2 1 ATOM 4764 N N . ASN A 1 599 ? -10.306 -9.837 17.986 1.00 14.06 ? 599 ASN A N 1 ATOM 4765 C CA . ASN A 1 599 ? -10.326 -11.041 17.156 1.00 15.48 ? 599 ASN A CA 1 ATOM 4766 C C . ASN A 1 599 ? -8.858 -11.266 16.750 1.00 15.62 ? 599 ASN A C 1 ATOM 4767 O O . ASN A 1 599 ? -8.247 -10.395 16.110 1.00 17.63 ? 599 ASN A O 1 ATOM 4768 C CB . ASN A 1 599 ? -11.220 -10.749 15.924 1.00 15.17 ? 599 ASN A CB 1 ATOM 4769 C CG . ASN A 1 599 ? -11.352 -11.938 14.938 1.00 17.33 ? 599 ASN A CG 1 ATOM 4770 O OD1 . ASN A 1 599 ? -10.385 -12.646 14.634 1.00 18.51 ? 599 ASN A OD1 1 ATOM 4771 N ND2 . ASN A 1 599 ? -12.568 -12.115 14.393 1.00 17.94 ? 599 ASN A ND2 1 ATOM 4772 N N . HIS A 1 600 ? -8.304 -12.413 17.133 1.00 15.97 ? 600 HIS A N 1 ATOM 4773 C CA . HIS A 1 600 ? -6.905 -12.777 16.849 1.00 15.94 ? 600 HIS A CA 1 ATOM 4774 C C . HIS A 1 600 ? -6.863 -14.251 16.411 1.00 16.71 ? 600 HIS A C 1 ATOM 4775 O O . HIS A 1 600 ? -7.714 -15.054 16.816 1.00 17.65 ? 600 HIS A O 1 ATOM 4776 C CB . HIS A 1 600 ? -6.061 -12.510 18.083 1.00 15.78 ? 600 HIS A CB 1 ATOM 4777 C CG . HIS A 1 600 ? -4.618 -12.896 17.946 1.00 14.22 ? 600 HIS A CG 1 ATOM 4778 N ND1 . HIS A 1 600 ? -3.819 -12.437 16.922 1.00 15.29 ? 600 HIS A ND1 1 ATOM 4779 C CD2 . HIS A 1 600 ? -3.818 -13.639 18.745 1.00 15.71 ? 600 HIS A CD2 1 ATOM 4780 C CE1 . HIS A 1 600 ? -2.588 -12.902 17.078 1.00 16.87 ? 600 HIS A CE1 1 ATOM 4781 N NE2 . HIS A 1 600 ? -2.559 -13.634 18.178 1.00 16.55 ? 600 HIS A NE2 1 ATOM 4782 N N . ASN A 1 601 ? -5.893 -14.628 15.577 1.00 16.20 ? 601 ASN A N 1 ATOM 4783 C CA . ASN A 1 601 ? -5.940 -15.945 14.946 1.00 16.43 ? 601 ASN A CA 1 ATOM 4784 C C . ASN A 1 601 ? -4.508 -16.434 14.864 1.00 16.15 ? 601 ASN A C 1 ATOM 4785 O O . ASN A 1 601 ? -3.596 -15.617 14.706 1.00 16.80 ? 601 ASN A O 1 ATOM 4786 C CB . ASN A 1 601 ? -6.510 -15.771 13.543 1.00 14.60 ? 601 ASN A CB 1 ATOM 4787 C CG . ASN A 1 601 ? -6.816 -17.085 12.817 1.00 15.81 ? 601 ASN A CG 1 ATOM 4788 O OD1 . ASN A 1 601 ? -6.887 -18.163 13.395 1.00 16.88 ? 601 ASN A OD1 1 ATOM 4789 N ND2 . ASN A 1 601 ? -6.997 -16.976 11.512 1.00 19.09 ? 601 ASN A ND2 1 ATOM 4790 N N . GLY A 1 602 ? -4.309 -17.741 14.999 1.00 16.86 ? 602 GLY A N 1 ATOM 4791 C CA . GLY A 1 602 ? -2.960 -18.324 14.916 1.00 16.13 ? 602 GLY A CA 1 ATOM 4792 C C . GLY A 1 602 ? -2.434 -18.445 13.498 1.00 17.78 ? 602 GLY A C 1 ATOM 4793 O O . GLY A 1 602 ? -3.097 -18.084 12.536 1.00 17.50 ? 602 GLY A O 1 ATOM 4794 N N . GLN A 1 603 ? -1.213 -18.952 13.381 1.00 18.82 ? 603 GLN A N 1 ATOM 4795 C CA . GLN A 1 603 ? -0.498 -19.024 12.122 1.00 21.67 ? 603 GLN A CA 1 ATOM 4796 C C . GLN A 1 603 ? -1.105 -20.094 11.241 1.00 22.23 ? 603 GLN A C 1 ATOM 4797 O O . GLN A 1 603 ? -1.361 -21.203 11.707 1.00 22.71 ? 603 GLN A O 1 ATOM 4798 C CB . GLN A 1 603 ? 0.961 -19.384 12.425 1.00 21.54 ? 603 GLN A CB 1 ATOM 4799 C CG . GLN A 1 603 ? 1.902 -19.368 11.232 1.00 25.18 ? 603 GLN A CG 1 ATOM 4800 C CD . GLN A 1 603 ? 3.321 -19.818 11.623 1.00 25.75 ? 603 GLN A CD 1 ATOM 4801 O OE1 . GLN A 1 603 ? 3.509 -20.697 12.474 1.00 32.53 ? 603 GLN A OE1 1 ATOM 4802 N NE2 . GLN A 1 603 ? 4.317 -19.224 10.988 1.00 33.12 ? 603 GLN A NE2 1 ATOM 4803 N N . GLY A 1 604 ? -1.358 -19.740 9.979 1.00 22.39 ? 604 GLY A N 1 ATOM 4804 C CA . GLY A 1 604 ? -1.711 -20.724 8.964 1.00 23.11 ? 604 GLY A CA 1 ATOM 4805 C C . GLY A 1 604 ? -3.186 -21.005 8.838 1.00 22.67 ? 604 GLY A C 1 ATOM 4806 O O . GLY A 1 604 ? -3.622 -21.493 7.795 1.00 22.77 ? 604 GLY A O 1 ATOM 4807 N N . TYR A 1 605 ? -3.977 -20.679 9.862 1.00 21.72 ? 605 TYR A N 1 ATOM 4808 C CA . TYR A 1 605 ? -5.417 -20.967 9.815 1.00 21.63 ? 605 TYR A CA 1 ATOM 4809 C C . TYR A 1 605 ? -6.173 -20.031 8.858 1.00 22.04 ? 605 TYR A C 1 ATOM 4810 O O . TYR A 1 605 ? -5.713 -18.945 8.551 1.00 22.85 ? 605 TYR A O 1 ATOM 4811 C CB . TYR A 1 605 ? -6.056 -20.974 11.236 1.00 22.14 ? 605 TYR A CB 1 ATOM 4812 C CG . TYR A 1 605 ? -5.238 -21.803 12.181 1.00 21.35 ? 605 TYR A CG 1 ATOM 4813 C CD1 . TYR A 1 605 ? -5.156 -23.192 12.022 1.00 22.80 ? 605 TYR A CD1 1 ATOM 4814 C CD2 . TYR A 1 605 ? -4.497 -21.205 13.195 1.00 21.91 ? 605 TYR A CD2 1 ATOM 4815 C CE1 . TYR A 1 605 ? -4.344 -23.960 12.864 1.00 25.29 ? 605 TYR A CE1 1 ATOM 4816 C CE2 . TYR A 1 605 ? -3.692 -21.945 14.025 1.00 22.97 ? 605 TYR A CE2 1 ATOM 4817 C CZ . TYR A 1 605 ? -3.618 -23.316 13.862 1.00 23.50 ? 605 TYR A CZ 1 ATOM 4818 O OH . TYR A 1 605 ? -2.829 -24.031 14.721 1.00 24.96 ? 605 TYR A OH 1 ATOM 4819 N N . LYS A 1 606 ? -7.315 -20.509 8.377 1.00 22.24 ? 606 LYS A N 1 ATOM 4820 C CA . LYS A 1 606 ? -8.274 -19.752 7.562 1.00 24.33 ? 606 LYS A CA 1 ATOM 4821 C C . LYS A 1 606 ? -8.521 -18.388 8.216 1.00 23.57 ? 606 LYS A C 1 ATOM 4822 O O . LYS A 1 606 ? -8.503 -18.287 9.442 1.00 23.70 ? 606 LYS A O 1 ATOM 4823 C CB . LYS A 1 606 ? -9.561 -20.596 7.459 1.00 23.50 ? 606 LYS A CB 1 ATOM 4824 C CG . LYS A 1 606 ? -10.832 -19.870 7.130 1.00 27.61 ? 606 LYS A CG 1 ATOM 4825 C CD . LYS A 1 606 ? -12.035 -20.855 7.154 1.00 27.89 ? 606 LYS A CD 1 ATOM 4826 C CE . LYS A 1 606 ? -13.374 -20.089 7.261 1.00 35.12 ? 606 LYS A CE 1 ATOM 4827 N NZ . LYS A 1 606 ? -14.495 -20.948 7.812 1.00 36.52 ? 606 LYS A NZ 1 ATOM 4828 N N . ASP A 1 607 ? -8.677 -17.346 7.398 1.00 23.15 ? 607 ASP A N 1 ATOM 4829 C CA . ASP A 1 607 ? -8.936 -15.987 7.878 1.00 22.08 ? 607 ASP A CA 1 ATOM 4830 C C . ASP A 1 607 ? -10.203 -16.002 8.724 1.00 21.32 ? 607 ASP A C 1 ATOM 4831 O O . ASP A 1 607 ? -11.193 -16.679 8.400 1.00 20.78 ? 607 ASP A O 1 ATOM 4832 C CB . ASP A 1 607 ? -9.134 -15.036 6.690 1.00 22.44 ? 607 ASP A CB 1 ATOM 4833 C CG . ASP A 1 607 ? -7.867 -14.782 5.916 1.00 25.34 ? 607 ASP A CG 1 ATOM 4834 O OD1 . ASP A 1 607 ? -6.770 -15.141 6.402 1.00 28.82 ? 607 ASP A OD1 1 ATOM 4835 O OD2 . ASP A 1 607 ? -7.955 -14.206 4.810 1.00 26.90 ? 607 ASP A OD2 1 ATOM 4836 N N . GLN A 1 608 ? -10.197 -15.227 9.796 1.00 19.78 ? 608 GLN A N 1 ATOM 4837 C CA . GLN A 1 608 ? -11.409 -15.132 10.596 1.00 18.53 ? 608 GLN A CA 1 ATOM 4838 C C . GLN A 1 608 ? -11.766 -13.698 10.982 1.00 17.70 ? 608 GLN A C 1 ATOM 4839 O O . GLN A 1 608 ? -12.567 -13.491 11.882 1.00 17.60 ? 608 GLN A O 1 ATOM 4840 C CB . GLN A 1 608 ? -11.288 -16.046 11.825 1.00 17.99 ? 608 GLN A CB 1 ATOM 4841 C CG . GLN A 1 608 ? -10.234 -15.639 12.794 1.00 18.64 ? 608 GLN A CG 1 ATOM 4842 C CD . GLN A 1 608 ? -9.988 -16.678 13.876 1.00 18.83 ? 608 GLN A CD 1 ATOM 4843 O OE1 . GLN A 1 608 ? -9.958 -17.884 13.619 1.00 20.16 ? 608 GLN A OE1 1 ATOM 4844 N NE2 . GLN A 1 608 ? -9.804 -16.204 15.106 1.00 17.92 ? 608 GLN A NE2 1 ATOM 4845 N N . ASP A 1 609 ? -11.163 -12.711 10.305 1.00 17.29 ? 609 ASP A N 1 ATOM 4846 C CA . ASP A 1 609 ? -11.537 -11.334 10.477 1.00 16.81 ? 609 ASP A CA 1 ATOM 4847 C C . ASP A 1 609 ? -12.980 -11.239 9.980 1.00 18.04 ? 609 ASP A C 1 ATOM 4848 O O . ASP A 1 609 ? -13.382 -12.006 9.091 1.00 18.35 ? 609 ASP A O 1 ATOM 4849 C CB . ASP A 1 609 ? -10.616 -10.388 9.690 1.00 17.87 ? 609 ASP A CB 1 ATOM 4850 C CG . ASP A 1 609 ? -10.557 -10.725 8.238 1.00 17.25 ? 609 ASP A CG 1 ATOM 4851 O OD1 . ASP A 1 609 ? -9.822 -11.659 7.869 1.00 18.74 ? 609 ASP A OD1 1 ATOM 4852 O OD2 . ASP A 1 609 ? -11.236 -10.049 7.456 1.00 18.49 ? 609 ASP A OD2 1 ATOM 4853 N N . PRO A 1 610 ? -13.781 -10.365 10.596 1.00 17.88 ? 610 PRO A N 1 ATOM 4854 C CA . PRO A 1 610 ? -15.215 -10.308 10.262 1.00 18.67 ? 610 PRO A CA 1 ATOM 4855 C C . PRO A 1 610 ? -15.550 -10.193 8.759 1.00 18.98 ? 610 PRO A C 1 ATOM 4856 O O . PRO A 1 610 ? -16.392 -10.937 8.276 1.00 19.31 ? 610 PRO A O 1 ATOM 4857 C CB . PRO A 1 610 ? -15.695 -9.093 11.059 1.00 17.30 ? 610 PRO A CB 1 ATOM 4858 C CG . PRO A 1 610 ? -14.782 -9.092 12.280 1.00 18.14 ? 610 PRO A CG 1 ATOM 4859 C CD . PRO A 1 610 ? -13.436 -9.408 11.667 1.00 19.26 ? 610 PRO A CD 1 ATOM 4860 N N . ALA A 1 611 ? -14.877 -9.305 8.021 1.00 19.47 ? 611 ALA A N 1 ATOM 4861 C CA . ALA A 1 611 ? -15.199 -9.106 6.599 1.00 19.89 ? 611 ALA A CA 1 ATOM 4862 C C . ALA A 1 611 ? -14.773 -10.271 5.701 1.00 20.57 ? 611 ALA A C 1 ATOM 4863 O O . ALA A 1 611 ? -15.233 -10.380 4.563 1.00 20.04 ? 611 ALA A O 1 ATOM 4864 C CB . ALA A 1 611 ? -14.631 -7.796 6.084 1.00 18.85 ? 611 ALA A CB 1 ATOM 4865 N N . SER A 1 612 ? -13.934 -11.171 6.222 1.00 21.31 ? 612 SER A N 1 ATOM 4866 C CA . SER A 1 612 ? -13.486 -12.334 5.443 1.00 22.45 ? 612 SER A CA 1 ATOM 4867 C C . SER A 1 612 ? -14.607 -13.350 5.231 1.00 23.11 ? 612 SER A C 1 ATOM 4868 O O . SER A 1 612 ? -14.517 -14.207 4.343 1.00 23.49 ? 612 SER A O 1 ATOM 4869 C CB . SER A 1 612 ? -12.263 -13.017 6.079 1.00 21.91 ? 612 SER A CB 1 ATOM 4870 O OG . SER A 1 612 ? -12.668 -13.851 7.153 1.00 22.79 ? 612 SER A OG 1 ATOM 4871 N N . PHE A 1 613 ? -15.691 -13.210 5.993 1.00 23.36 ? 613 PHE A N 1 ATOM 4872 C CA . PHE A 1 613 ? -16.832 -14.112 5.859 1.00 23.67 ? 613 PHE A CA 1 ATOM 4873 C C . PHE A 1 613 ? -17.806 -13.709 4.748 1.00 24.47 ? 613 PHE A C 1 ATOM 4874 O O . PHE A 1 613 ? -18.726 -14.460 4.431 1.00 24.11 ? 613 PHE A O 1 ATOM 4875 C CB . PHE A 1 613 ? -17.554 -14.263 7.205 1.00 23.41 ? 613 PHE A CB 1 ATOM 4876 C CG . PHE A 1 613 ? -16.751 -15.010 8.212 1.00 23.48 ? 613 PHE A CG 1 ATOM 4877 C CD1 . PHE A 1 613 ? -16.942 -16.371 8.387 1.00 22.98 ? 613 PHE A CD1 1 ATOM 4878 C CD2 . PHE A 1 613 ? -15.787 -14.352 8.981 1.00 20.37 ? 613 PHE A CD2 1 ATOM 4879 C CE1 . PHE A 1 613 ? -16.173 -17.074 9.319 1.00 22.86 ? 613 PHE A CE1 1 ATOM 4880 C CE2 . PHE A 1 613 ? -15.032 -15.053 9.915 1.00 19.62 ? 613 PHE A CE2 1 ATOM 4881 C CZ . PHE A 1 613 ? -15.227 -16.415 10.067 1.00 22.33 ? 613 PHE A CZ 1 ATOM 4882 N N . GLY A 1 614 ? -17.577 -12.539 4.156 1.00 25.88 ? 614 GLY A N 1 ATOM 4883 C CA . GLY A 1 614 ? -18.404 -12.035 3.064 1.00 26.23 ? 614 GLY A CA 1 ATOM 4884 C C . GLY A 1 614 ? -18.985 -10.676 3.340 1.00 27.44 ? 614 GLY A C 1 ATOM 4885 O O . GLY A 1 614 ? -19.523 -10.427 4.437 1.00 26.97 ? 614 GLY A O 1 ATOM 4886 N N . ALA A 1 615 ? -18.916 -9.804 2.332 1.00 27.76 ? 615 ALA A N 1 ATOM 4887 C CA . ALA A 1 615 ? -19.328 -8.413 2.490 1.00 29.15 ? 615 ALA A CA 1 ATOM 4888 C C . ALA A 1 615 ? -20.786 -8.321 2.841 1.00 29.21 ? 615 ALA A C 1 ATOM 4889 O O . ALA A 1 615 ? -21.219 -7.314 3.395 1.00 31.00 ? 615 ALA A O 1 ATOM 4890 C CB . ALA A 1 615 ? -19.018 -7.584 1.220 1.00 29.83 ? 615 ALA A CB 1 ATOM 4891 N N . ASP A 1 616 ? -21.544 -9.373 2.548 1.00 29.88 ? 616 ASP A N 1 ATOM 4892 C CA . ASP A 1 616 ? -22.974 -9.388 2.836 1.00 29.93 ? 616 ASP A CA 1 ATOM 4893 C C . ASP A 1 616 ? -23.403 -10.572 3.724 1.00 27.85 ? 616 ASP A C 1 ATOM 4894 O O . ASP A 1 616 ? -24.577 -10.953 3.762 1.00 27.07 ? 616 ASP A O 1 ATOM 4895 C CB . ASP A 1 616 ? -23.796 -9.300 1.521 1.00 31.83 ? 616 ASP A CB 1 ATOM 4896 C CG . ASP A 1 616 ? -23.691 -7.914 0.842 1.00 36.65 ? 616 ASP A CG 1 ATOM 4897 O OD1 . ASP A 1 616 ? -23.511 -7.851 -0.403 1.00 42.66 ? 616 ASP A OD1 1 ATOM 4898 O OD2 . ASP A 1 616 ? -23.779 -6.870 1.542 1.00 40.76 ? 616 ASP A OD2 1 ATOM 4899 N N . SER A 1 617 ? -22.448 -11.131 4.473 1.00 25.15 ? 617 SER A N 1 ATOM 4900 C CA . SER A 1 617 ? -22.671 -12.345 5.262 1.00 23.12 ? 617 SER A CA 1 ATOM 4901 C C . SER A 1 617 ? -23.418 -12.029 6.552 1.00 22.50 ? 617 SER A C 1 ATOM 4902 O O . SER A 1 617 ? -23.338 -10.909 7.041 1.00 21.97 ? 617 SER A O 1 ATOM 4903 C CB . SER A 1 617 ? -21.342 -13.006 5.616 1.00 23.64 ? 617 SER A CB 1 ATOM 4904 O OG . SER A 1 617 ? -20.554 -12.150 6.433 1.00 22.09 ? 617 SER A OG 1 ATOM 4905 N N . LEU A 1 618 ? -24.129 -13.015 7.100 1.00 22.23 ? 618 LEU A N 1 ATOM 4906 C CA . LEU A 1 618 ? -24.772 -12.867 8.414 1.00 21.86 ? 618 LEU A CA 1 ATOM 4907 C C . LEU A 1 618 ? -23.740 -12.506 9.492 1.00 21.08 ? 618 LEU A C 1 ATOM 4908 O O . LEU A 1 618 ? -23.985 -11.657 10.350 1.00 20.00 ? 618 LEU A O 1 ATOM 4909 C CB . LEU A 1 618 ? -25.523 -14.134 8.809 1.00 22.35 ? 618 LEU A CB 1 ATOM 4910 C CG . LEU A 1 618 ? -26.293 -14.093 10.142 1.00 21.96 ? 618 LEU A CG 1 ATOM 4911 C CD1 . LEU A 1 618 ? -27.318 -12.981 10.159 1.00 25.97 ? 618 LEU A CD1 1 ATOM 4912 C CD2 . LEU A 1 618 ? -26.925 -15.461 10.396 1.00 23.00 ? 618 LEU A CD2 1 ATOM 4913 N N . LEU A 1 619 ? -22.568 -13.132 9.438 1.00 19.38 ? 619 LEU A N 1 ATOM 4914 C CA . LEU A 1 619 ? -21.570 -12.878 10.471 1.00 18.46 ? 619 LEU A CA 1 ATOM 4915 C C . LEU A 1 619 ? -21.127 -11.415 10.419 1.00 18.45 ? 619 LEU A C 1 ATOM 4916 O O . LEU A 1 619 ? -21.028 -10.766 11.458 1.00 18.19 ? 619 LEU A O 1 ATOM 4917 C CB . LEU A 1 619 ? -20.358 -13.821 10.305 1.00 18.49 ? 619 LEU A CB 1 ATOM 4918 C CG . LEU A 1 619 ? -19.262 -13.709 11.368 1.00 17.57 ? 619 LEU A CG 1 ATOM 4919 C CD1 . LEU A 1 619 ? -18.585 -15.046 11.530 1.00 17.42 ? 619 LEU A CD1 1 ATOM 4920 C CD2 . LEU A 1 619 ? -18.188 -12.609 11.055 1.00 16.81 ? 619 LEU A CD2 1 ATOM 4921 N N . LEU A 1 620 ? -20.843 -10.879 9.221 1.00 18.97 ? 620 LEU A N 1 ATOM 4922 C CA . LEU A 1 620 ? -20.307 -9.513 9.150 1.00 18.83 ? 620 LEU A CA 1 ATOM 4923 C C . LEU A 1 620 ? -21.380 -8.531 9.592 1.00 19.04 ? 620 LEU A C 1 ATOM 4924 O O . LEU A 1 620 ? -21.120 -7.616 10.377 1.00 17.88 ? 620 LEU A O 1 ATOM 4925 C CB . LEU A 1 620 ? -19.806 -9.159 7.741 1.00 19.94 ? 620 LEU A CB 1 ATOM 4926 C CG . LEU A 1 620 ? -19.384 -7.690 7.617 1.00 20.34 ? 620 LEU A CG 1 ATOM 4927 C CD1 . LEU A 1 620 ? -18.100 -7.466 8.448 1.00 19.26 ? 620 LEU A CD1 1 ATOM 4928 C CD2 . LEU A 1 620 ? -19.141 -7.324 6.152 1.00 24.51 ? 620 LEU A CD2 1 ATOM 4929 N N . ASN A 1 621 ? -22.587 -8.727 9.077 1.00 19.47 ? 621 ASN A N 1 ATOM 4930 C CA . ASN A 1 621 ? -23.737 -7.894 9.456 1.00 20.24 ? 621 ASN A CA 1 ATOM 4931 C C . ASN A 1 621 ? -23.971 -7.885 10.948 1.00 19.49 ? 621 ASN A C 1 ATOM 4932 O O . ASN A 1 621 ? -24.113 -6.817 11.550 1.00 18.67 ? 621 ASN A O 1 ATOM 4933 C CB . ASN A 1 621 ? -25.012 -8.354 8.744 1.00 21.77 ? 621 ASN A CB 1 ATOM 4934 C CG . ASN A 1 621 ? -24.986 -8.008 7.268 1.00 26.07 ? 621 ASN A CG 1 ATOM 4935 O OD1 . ASN A 1 621 ? -24.245 -7.112 6.840 1.00 29.73 ? 621 ASN A OD1 1 ATOM 4936 N ND2 . ASN A 1 621 ? -25.809 -8.694 6.482 1.00 32.36 ? 621 ASN A ND2 1 ATOM 4937 N N . SER A 1 622 ? -23.997 -9.066 11.546 1.00 19.73 ? 622 SER A N 1 ATOM 4938 C CA . SER A 1 622 ? -24.223 -9.135 12.988 1.00 19.73 ? 622 SER A CA 1 ATOM 4939 C C . SER A 1 622 ? -23.045 -8.558 13.804 1.00 18.24 ? 622 SER A C 1 ATOM 4940 O O . SER A 1 622 ? -23.240 -7.827 14.807 1.00 16.96 ? 622 SER A O 1 ATOM 4941 C CB . SER A 1 622 ? -24.529 -10.555 13.417 1.00 20.13 ? 622 SER A CB 1 ATOM 4942 O OG . SER A 1 622 ? -24.834 -10.503 14.781 1.00 24.96 ? 622 SER A OG 1 ATOM 4943 N N . SER A 1 623 ? -21.822 -8.892 13.393 1.00 17.38 ? 623 SER A N 1 ATOM 4944 C CA . SER A 1 623 ? -20.668 -8.291 14.015 1.00 17.70 ? 623 SER A CA 1 ATOM 4945 C C . SER A 1 623 ? -20.753 -6.788 14.011 1.00 17.59 ? 623 SER A C 1 ATOM 4946 O O . SER A 1 623 ? -20.557 -6.165 15.047 1.00 19.16 ? 623 SER A O 1 ATOM 4947 C CB . SER A 1 623 ? -19.367 -8.761 13.345 1.00 17.75 ? 623 SER A CB 1 ATOM 4948 O OG . SER A 1 623 ? -19.277 -10.152 13.462 1.00 17.59 ? 623 SER A OG 1 ATOM 4949 N N . ARG A 1 624 ? -21.035 -6.197 12.849 1.00 17.71 ? 624 ARG A N 1 ATOM 4950 C CA . ARG A 1 624 ? -21.109 -4.740 12.731 1.00 17.90 ? 624 ARG A CA 1 ATOM 4951 C C . ARG A 1 624 ? -22.216 -4.226 13.642 1.00 16.65 ? 624 ARG A C 1 ATOM 4952 O O . ARG A 1 624 ? -22.044 -3.234 14.313 1.00 15.11 ? 624 ARG A O 1 ATOM 4953 C CB . ARG A 1 624 ? -21.350 -4.303 11.253 1.00 17.98 ? 624 ARG A CB 1 ATOM 4954 C CG . ARG A 1 624 ? -21.434 -2.791 11.001 1.00 18.05 ? 624 ARG A CG 1 ATOM 4955 C CD . ARG A 1 624 ? -21.523 -2.527 9.456 1.00 20.30 ? 624 ARG A CD 1 ATOM 4956 N NE . ARG A 1 624 ? -22.518 -3.424 8.864 1.00 27.47 ? 624 ARG A NE 1 ATOM 4957 C CZ . ARG A 1 624 ? -22.372 -4.104 7.738 1.00 27.13 ? 624 ARG A CZ 1 ATOM 4958 N NH1 . ARG A 1 624 ? -21.253 -4.018 6.992 1.00 23.93 ? 624 ARG A NH1 1 ATOM 4959 N NH2 . ARG A 1 624 ? -23.366 -4.903 7.365 1.00 29.18 ? 624 ARG A NH2 1 ATOM 4960 N N . HIS A 1 625 ? -23.352 -4.926 13.653 1.00 16.57 ? 625 HIS A N 1 ATOM 4961 C CA . HIS A 1 625 ? -24.500 -4.496 14.431 1.00 16.42 ? 625 HIS A CA 1 ATOM 4962 C C . HIS A 1 625 ? -24.150 -4.386 15.923 1.00 15.62 ? 625 HIS A C 1 ATOM 4963 O O . HIS A 1 625 ? -24.391 -3.344 16.568 1.00 15.04 ? 625 HIS A O 1 ATOM 4964 C CB . HIS A 1 625 ? -25.671 -5.470 14.219 1.00 17.41 ? 625 HIS A CB 1 ATOM 4965 C CG . HIS A 1 625 ? -26.920 -5.052 14.924 1.00 19.40 ? 625 HIS A CG 1 ATOM 4966 N ND1 . HIS A 1 625 ? -27.401 -5.710 16.035 1.00 22.16 ? 625 HIS A ND1 1 ATOM 4967 C CD2 . HIS A 1 625 ? -27.764 -4.017 14.702 1.00 22.64 ? 625 HIS A CD2 1 ATOM 4968 C CE1 . HIS A 1 625 ? -28.503 -5.115 16.455 1.00 22.37 ? 625 HIS A CE1 1 ATOM 4969 N NE2 . HIS A 1 625 ? -28.741 -4.081 15.670 1.00 26.51 ? 625 HIS A NE2 1 ATOM 4970 N N . TYR A 1 626 ? -23.577 -5.450 16.469 1.00 14.54 ? 626 TYR A N 1 ATOM 4971 C CA . TYR A 1 626 ? -23.289 -5.482 17.903 1.00 15.17 ? 626 TYR A CA 1 ATOM 4972 C C . TYR A 1 626 ? -22.067 -4.688 18.292 1.00 14.28 ? 626 TYR A C 1 ATOM 4973 O O . TYR A 1 626 ? -22.011 -4.144 19.397 1.00 14.54 ? 626 TYR A O 1 ATOM 4974 C CB . TYR A 1 626 ? -23.233 -6.931 18.430 1.00 14.79 ? 626 TYR A CB 1 ATOM 4975 C CG . TYR A 1 626 ? -24.634 -7.474 18.540 1.00 17.88 ? 626 TYR A CG 1 ATOM 4976 C CD1 . TYR A 1 626 ? -25.090 -8.489 17.693 1.00 16.82 ? 626 TYR A CD1 1 ATOM 4977 C CD2 . TYR A 1 626 ? -25.514 -6.941 19.484 1.00 13.25 ? 626 TYR A CD2 1 ATOM 4978 C CE1 . TYR A 1 626 ? -26.408 -8.958 17.793 1.00 16.48 ? 626 TYR A CE1 1 ATOM 4979 C CE2 . TYR A 1 626 ? -26.832 -7.386 19.575 1.00 18.23 ? 626 TYR A CE2 1 ATOM 4980 C CZ . TYR A 1 626 ? -27.251 -8.405 18.732 1.00 17.25 ? 626 TYR A CZ 1 ATOM 4981 O OH . TYR A 1 626 ? -28.532 -8.869 18.848 1.00 17.39 ? 626 TYR A OH 1 ATOM 4982 N N . LEU A 1 627 ? -21.086 -4.608 17.411 1.00 13.91 ? 627 LEU A N 1 ATOM 4983 C CA . LEU A 1 627 ? -19.997 -3.647 17.665 1.00 13.36 ? 627 LEU A CA 1 ATOM 4984 C C . LEU A 1 627 ? -20.534 -2.218 17.639 1.00 13.95 ? 627 LEU A C 1 ATOM 4985 O O . LEU A 1 627 ? -20.028 -1.351 18.321 1.00 14.05 ? 627 LEU A O 1 ATOM 4986 C CB . LEU A 1 627 ? -18.859 -3.810 16.666 1.00 11.78 ? 627 LEU A CB 1 ATOM 4987 C CG . LEU A 1 627 ? -17.959 -5.020 16.975 1.00 13.37 ? 627 LEU A CG 1 ATOM 4988 C CD1 . LEU A 1 627 ? -17.051 -5.165 15.781 1.00 13.76 ? 627 LEU A CD1 1 ATOM 4989 C CD2 . LEU A 1 627 ? -17.209 -4.805 18.291 1.00 14.31 ? 627 LEU A CD2 1 ATOM 4990 N N . ASN A 1 628 ? -21.575 -1.952 16.847 1.00 14.56 ? 628 ASN A N 1 ATOM 4991 C CA . ASN A 1 628 ? -22.089 -0.602 16.845 1.00 14.84 ? 628 ASN A CA 1 ATOM 4992 C C . ASN A 1 628 ? -22.792 -0.301 18.164 1.00 14.23 ? 628 ASN A C 1 ATOM 4993 O O . ASN A 1 628 ? -22.741 0.821 18.664 1.00 14.98 ? 628 ASN A O 1 ATOM 4994 C CB . ASN A 1 628 ? -23.000 -0.345 15.641 1.00 15.68 ? 628 ASN A CB 1 ATOM 4995 C CG . ASN A 1 628 ? -22.235 0.194 14.441 1.00 19.10 ? 628 ASN A CG 1 ATOM 4996 O OD1 . ASN A 1 628 ? -22.558 -0.112 13.277 1.00 24.38 ? 628 ASN A OD1 1 ATOM 4997 N ND2 . ASN A 1 628 ? -21.258 1.013 14.709 1.00 16.32 ? 628 ASN A ND2 1 ATOM 4998 N N . ILE A 1 629 ? -23.440 -1.319 18.726 1.00 14.19 ? 629 ILE A N 1 ATOM 4999 C CA . ILE A 1 629 ? -24.023 -1.223 20.072 1.00 12.73 ? 629 ILE A CA 1 ATOM 5000 C C . ILE A 1 629 ? -22.933 -1.036 21.105 1.00 12.40 ? 629 ILE A C 1 ATOM 5001 O O . ILE A 1 629 ? -23.035 -0.191 21.968 1.00 12.70 ? 629 ILE A O 1 ATOM 5002 C CB . ILE A 1 629 ? -24.912 -2.460 20.402 1.00 12.51 ? 629 ILE A CB 1 ATOM 5003 C CG1 . ILE A 1 629 ? -26.206 -2.348 19.554 1.00 12.32 ? 629 ILE A CG1 1 ATOM 5004 C CG2 . ILE A 1 629 ? -25.243 -2.455 21.942 1.00 12.14 ? 629 ILE A CG2 1 ATOM 5005 C CD1 . ILE A 1 629 ? -27.066 -3.627 19.536 1.00 13.20 ? 629 ILE A CD1 1 ATOM 5006 N N . ARG A 1 630 ? -21.874 -1.834 21.046 1.00 12.15 ? 630 ARG A N 1 ATOM 5007 C CA . ARG A 1 630 ? -20.743 -1.571 21.969 1.00 12.26 ? 630 ARG A CA 1 ATOM 5008 C C . ARG A 1 630 ? -20.279 -0.118 21.935 1.00 11.88 ? 630 ARG A C 1 ATOM 5009 O O . ARG A 1 630 ? -20.108 0.516 23.005 1.00 11.86 ? 630 ARG A O 1 ATOM 5010 C CB . ARG A 1 630 ? -19.544 -2.478 21.644 1.00 11.05 ? 630 ARG A CB 1 ATOM 5011 C CG . ARG A 1 630 ? -18.311 -2.161 22.523 1.00 11.28 ? 630 ARG A CG 1 ATOM 5012 C CD . ARG A 1 630 ? -17.021 -2.747 21.865 1.00 11.63 ? 630 ARG A CD 1 ATOM 5013 N NE . ARG A 1 630 ? -15.877 -2.626 22.782 1.00 12.63 ? 630 ARG A NE 1 ATOM 5014 C CZ . ARG A 1 630 ? -15.593 -3.464 23.787 1.00 14.52 ? 630 ARG A CZ 1 ATOM 5015 N NH1 . ARG A 1 630 ? -16.370 -4.513 24.037 1.00 16.24 ? 630 ARG A NH1 1 ATOM 5016 N NH2 . ARG A 1 630 ? -14.495 -3.270 24.536 1.00 16.38 ? 630 ARG A NH2 1 ATOM 5017 N N . TYR A 1 631 ? -20.033 0.397 20.725 1.00 12.15 ? 631 TYR A N 1 ATOM 5018 C CA . TYR A 1 631 ? -19.501 1.759 20.558 1.00 13.47 ? 631 TYR A CA 1 ATOM 5019 C C . TYR A 1 631 ? -20.522 2.784 21.075 1.00 12.80 ? 631 TYR A C 1 ATOM 5020 O O . TYR A 1 631 ? -20.171 3.728 21.771 1.00 14.07 ? 631 TYR A O 1 ATOM 5021 C CB . TYR A 1 631 ? -19.136 2.027 19.085 1.00 13.71 ? 631 TYR A CB 1 ATOM 5022 C CG . TYR A 1 631 ? -17.721 1.556 18.719 1.00 14.62 ? 631 TYR A CG 1 ATOM 5023 C CD1 . TYR A 1 631 ? -17.319 0.230 18.933 1.00 15.81 ? 631 TYR A CD1 1 ATOM 5024 C CD2 . TYR A 1 631 ? -16.795 2.443 18.181 1.00 15.80 ? 631 TYR A CD2 1 ATOM 5025 C CE1 . TYR A 1 631 ? -16.032 -0.211 18.598 1.00 14.56 ? 631 TYR A CE1 1 ATOM 5026 C CE2 . TYR A 1 631 ? -15.475 2.004 17.841 1.00 16.97 ? 631 TYR A CE2 1 ATOM 5027 C CZ . TYR A 1 631 ? -15.109 0.712 18.073 1.00 16.77 ? 631 TYR A CZ 1 ATOM 5028 O OH . TYR A 1 631 ? -13.832 0.308 17.721 1.00 14.95 ? 631 TYR A OH 1 ATOM 5029 N N . THR A 1 632 ? -21.803 2.523 20.834 1.00 13.80 ? 632 THR A N 1 ATOM 5030 C CA . THR A 1 632 ? -22.879 3.394 21.366 1.00 12.47 ? 632 THR A CA 1 ATOM 5031 C C . THR A 1 632 ? -22.808 3.517 22.892 1.00 13.56 ? 632 THR A C 1 ATOM 5032 O O . THR A 1 632 ? -22.996 4.591 23.448 1.00 13.78 ? 632 THR A O 1 ATOM 5033 C CB . THR A 1 632 ? -24.290 2.841 20.980 1.00 12.52 ? 632 THR A CB 1 ATOM 5034 O OG1 . THR A 1 632 ? -24.414 2.784 19.558 1.00 13.28 ? 632 THR A OG1 1 ATOM 5035 C CG2 . THR A 1 632 ? -25.389 3.755 21.541 1.00 14.78 ? 632 THR A CG2 1 ATOM 5036 N N . LEU A 1 633 ? -22.475 2.414 23.555 1.00 12.91 ? 633 LEU A N 1 ATOM 5037 C CA . LEU A 1 633 ? -22.369 2.370 25.016 1.00 14.01 ? 633 LEU A CA 1 ATOM 5038 C C . LEU A 1 633 ? -20.967 2.661 25.549 1.00 14.05 ? 633 LEU A C 1 ATOM 5039 O O . LEU A 1 633 ? -20.743 2.509 26.728 1.00 13.86 ? 633 LEU A O 1 ATOM 5040 C CB . LEU A 1 633 ? -22.841 1.013 25.558 1.00 13.98 ? 633 LEU A CB 1 ATOM 5041 C CG . LEU A 1 633 ? -24.339 0.766 25.294 1.00 15.75 ? 633 LEU A CG 1 ATOM 5042 C CD1 . LEU A 1 633 ? -24.631 -0.738 25.501 1.00 16.79 ? 633 LEU A CD1 1 ATOM 5043 C CD2 . LEU A 1 633 ? -25.168 1.613 26.234 1.00 16.71 ? 633 LEU A CD2 1 ATOM 5044 N N . LEU A 1 634 ? -20.050 3.118 24.706 1.00 14.12 ? 634 LEU A N 1 ATOM 5045 C CA . LEU A 1 634 ? -18.723 3.436 25.234 1.00 14.78 ? 634 LEU A CA 1 ATOM 5046 C C . LEU A 1 634 ? -18.653 4.457 26.379 1.00 13.97 ? 634 LEU A C 1 ATOM 5047 O O . LEU A 1 634 ? -17.830 4.286 27.259 1.00 14.66 ? 634 LEU A O 1 ATOM 5048 C CB . LEU A 1 634 ? -17.703 3.742 24.118 1.00 14.21 ? 634 LEU A CB 1 ATOM 5049 C CG . LEU A 1 634 ? -17.201 2.537 23.292 1.00 19.28 ? 634 LEU A CG 1 ATOM 5050 C CD1 . LEU A 1 634 ? -16.260 3.027 22.190 1.00 18.95 ? 634 LEU A CD1 1 ATOM 5051 C CD2 . LEU A 1 634 ? -16.510 1.490 24.138 1.00 20.49 ? 634 LEU A CD2 1 ATOM 5052 N N . PRO A 1 635 ? -19.474 5.545 26.370 1.00 13.76 ? 635 PRO A N 1 ATOM 5053 C CA . PRO A 1 635 ? -19.447 6.415 27.529 1.00 14.19 ? 635 PRO A CA 1 ATOM 5054 C C . PRO A 1 635 ? -19.825 5.681 28.828 1.00 13.58 ? 635 PRO A C 1 ATOM 5055 O O . PRO A 1 635 ? -19.298 5.984 29.852 1.00 14.02 ? 635 PRO A O 1 ATOM 5056 C CB . PRO A 1 635 ? -20.513 7.498 27.181 1.00 14.64 ? 635 PRO A CB 1 ATOM 5057 C CG . PRO A 1 635 ? -20.440 7.568 25.688 1.00 13.21 ? 635 PRO A CG 1 ATOM 5058 C CD . PRO A 1 635 ? -20.374 6.094 25.329 1.00 14.42 ? 635 PRO A CD 1 ATOM 5059 N N . TYR A 1 636 ? -20.763 4.745 28.766 1.00 12.84 ? 636 TYR A N 1 ATOM 5060 C CA . TYR A 1 636 ? -21.102 3.918 29.922 1.00 13.01 ? 636 TYR A CA 1 ATOM 5061 C C . TYR A 1 636 ? -19.879 3.017 30.296 1.00 12.10 ? 636 TYR A C 1 ATOM 5062 O O . TYR A 1 636 ? -19.434 2.983 31.447 1.00 12.47 ? 636 TYR A O 1 ATOM 5063 C CB . TYR A 1 636 ? -22.344 3.092 29.575 1.00 13.57 ? 636 TYR A CB 1 ATOM 5064 C CG . TYR A 1 636 ? -22.782 2.119 30.650 1.00 13.53 ? 636 TYR A CG 1 ATOM 5065 C CD1 . TYR A 1 636 ? -23.135 2.543 31.938 1.00 15.73 ? 636 TYR A CD1 1 ATOM 5066 C CD2 . TYR A 1 636 ? -22.830 0.763 30.359 1.00 13.17 ? 636 TYR A CD2 1 ATOM 5067 C CE1 . TYR A 1 636 ? -23.522 1.608 32.944 1.00 16.33 ? 636 TYR A CE1 1 ATOM 5068 C CE2 . TYR A 1 636 ? -23.206 -0.169 31.329 1.00 14.86 ? 636 TYR A CE2 1 ATOM 5069 C CZ . TYR A 1 636 ? -23.565 0.258 32.605 1.00 14.26 ? 636 TYR A CZ 1 ATOM 5070 O OH . TYR A 1 636 ? -23.892 -0.713 33.524 1.00 15.27 ? 636 TYR A OH 1 ATOM 5071 N N . LEU A 1 637 ? -19.350 2.299 29.327 1.00 11.92 ? 637 LEU A N 1 ATOM 5072 C CA . LEU A 1 637 ? -18.207 1.383 29.604 1.00 11.88 ? 637 LEU A CA 1 ATOM 5073 C C . LEU A 1 637 ? -17.013 2.178 30.157 1.00 12.03 ? 637 LEU A C 1 ATOM 5074 O O . LEU A 1 637 ? -16.320 1.725 31.082 1.00 11.66 ? 637 LEU A O 1 ATOM 5075 C CB . LEU A 1 637 ? -17.806 0.615 28.340 1.00 12.30 ? 637 LEU A CB 1 ATOM 5076 C CG . LEU A 1 637 ? -16.593 -0.344 28.514 1.00 12.88 ? 637 LEU A CG 1 ATOM 5077 C CD1 . LEU A 1 637 ? -16.925 -1.473 29.502 1.00 15.52 ? 637 LEU A CD1 1 ATOM 5078 C CD2 . LEU A 1 637 ? -16.259 -0.900 27.160 1.00 14.38 ? 637 LEU A CD2 1 ATOM 5079 N N . TYR A 1 638 ? -16.761 3.352 29.588 1.00 12.47 ? 638 TYR A N 1 ATOM 5080 C CA . TYR A 1 638 ? -15.591 4.180 30.039 1.00 11.47 ? 638 TYR A CA 1 ATOM 5081 C C . TYR A 1 638 ? -15.809 4.678 31.456 1.00 11.90 ? 638 TYR A C 1 ATOM 5082 O O . TYR A 1 638 ? -14.910 4.767 32.280 1.00 11.08 ? 638 TYR A O 1 ATOM 5083 C CB . TYR A 1 638 ? -15.449 5.374 29.105 1.00 12.00 ? 638 TYR A CB 1 ATOM 5084 C CG . TYR A 1 638 ? -14.182 6.187 29.283 1.00 13.56 ? 638 TYR A CG 1 ATOM 5085 C CD1 . TYR A 1 638 ? -12.935 5.566 29.228 1.00 12.50 ? 638 TYR A CD1 1 ATOM 5086 C CD2 . TYR A 1 638 ? -14.240 7.546 29.475 1.00 10.95 ? 638 TYR A CD2 1 ATOM 5087 C CE1 . TYR A 1 638 ? -11.749 6.315 29.353 1.00 12.03 ? 638 TYR A CE1 1 ATOM 5088 C CE2 . TYR A 1 638 ? -13.083 8.311 29.598 1.00 13.86 ? 638 TYR A CE2 1 ATOM 5089 C CZ . TYR A 1 638 ? -11.844 7.691 29.539 1.00 14.47 ? 638 TYR A CZ 1 ATOM 5090 O OH . TYR A 1 638 ? -10.697 8.488 29.647 1.00 13.65 ? 638 TYR A OH 1 ATOM 5091 N N . THR A 1 639 ? -17.056 5.031 31.781 1.00 10.47 ? 639 THR A N 1 ATOM 5092 C CA . THR A 1 639 ? -17.320 5.439 33.141 1.00 9.56 ? 639 THR A CA 1 ATOM 5093 C C . THR A 1 639 ? -17.142 4.264 34.116 1.00 9.55 ? 639 THR A C 1 ATOM 5094 O O . THR A 1 639 ? -16.727 4.476 35.258 1.00 11.09 ? 639 THR A O 1 ATOM 5095 C CB . THR A 1 639 ? -18.775 6.005 33.270 1.00 8.83 ? 639 THR A CB 1 ATOM 5096 O OG1 . THR A 1 639 ? -18.879 7.113 32.396 1.00 11.28 ? 639 THR A OG1 1 ATOM 5097 C CG2 . THR A 1 639 ? -19.051 6.494 34.676 1.00 12.48 ? 639 THR A CG2 1 ATOM 5098 N N . LEU A 1 640 ? -17.503 3.057 33.691 1.00 9.94 ? 640 LEU A N 1 ATOM 5099 C CA . LEU A 1 640 ? -17.230 1.851 34.481 1.00 10.56 ? 640 LEU A CA 1 ATOM 5100 C C . LEU A 1 640 ? -15.733 1.673 34.702 1.00 11.12 ? 640 LEU A C 1 ATOM 5101 O O . LEU A 1 640 ? -15.315 1.335 35.806 1.00 10.65 ? 640 LEU A O 1 ATOM 5102 C CB . LEU A 1 640 ? -17.782 0.608 33.814 1.00 10.47 ? 640 LEU A CB 1 ATOM 5103 C CG . LEU A 1 640 ? -19.302 0.562 33.714 1.00 10.12 ? 640 LEU A CG 1 ATOM 5104 C CD1 . LEU A 1 640 ? -19.667 -0.724 33.070 1.00 10.44 ? 640 LEU A CD1 1 ATOM 5105 C CD2 . LEU A 1 640 ? -19.907 0.699 35.130 1.00 12.36 ? 640 LEU A CD2 1 ATOM 5106 N N . PHE A 1 641 ? -14.944 1.910 33.666 1.00 12.10 ? 641 PHE A N 1 ATOM 5107 C CA . PHE A 1 641 ? -13.477 1.888 33.858 1.00 13.65 ? 641 PHE A CA 1 ATOM 5108 C C . PHE A 1 641 ? -12.962 2.972 34.791 1.00 12.74 ? 641 PHE A C 1 ATOM 5109 O O . PHE A 1 641 ? -11.986 2.752 35.541 1.00 12.25 ? 641 PHE A O 1 ATOM 5110 C CB . PHE A 1 641 ? -12.727 1.930 32.528 1.00 14.16 ? 641 PHE A CB 1 ATOM 5111 C CG . PHE A 1 641 ? -12.572 0.590 31.868 1.00 14.51 ? 641 PHE A CG 1 ATOM 5112 C CD1 . PHE A 1 641 ? -11.542 -0.277 32.261 1.00 15.18 ? 641 PHE A CD1 1 ATOM 5113 C CD2 . PHE A 1 641 ? -13.454 0.199 30.873 1.00 13.57 ? 641 PHE A CD2 1 ATOM 5114 C CE1 . PHE A 1 641 ? -11.401 -1.508 31.656 1.00 13.82 ? 641 PHE A CE1 1 ATOM 5115 C CE2 . PHE A 1 641 ? -13.336 -1.026 30.245 1.00 16.15 ? 641 PHE A CE2 1 ATOM 5116 C CZ . PHE A 1 641 ? -12.288 -1.898 30.641 1.00 15.23 ? 641 PHE A CZ 1 ATOM 5117 N N . PHE A 1 642 ? -13.557 4.170 34.722 1.00 13.20 ? 642 PHE A N 1 ATOM 5118 C CA . PHE A 1 642 ? -13.264 5.216 35.674 1.00 12.09 ? 642 PHE A CA 1 ATOM 5119 C C . PHE A 1 642 ? -13.532 4.744 37.106 1.00 12.34 ? 642 PHE A C 1 ATOM 5120 O O . PHE A 1 642 ? -12.726 4.999 38.015 1.00 10.82 ? 642 PHE A O 1 ATOM 5121 C CB . PHE A 1 642 ? -14.061 6.550 35.389 1.00 13.05 ? 642 PHE A CB 1 ATOM 5122 C CG . PHE A 1 642 ? -14.093 7.484 36.546 1.00 13.53 ? 642 PHE A CG 1 ATOM 5123 C CD1 . PHE A 1 642 ? -12.924 8.153 36.984 1.00 15.22 ? 642 PHE A CD1 1 ATOM 5124 C CD2 . PHE A 1 642 ? -15.293 7.722 37.228 1.00 17.29 ? 642 PHE A CD2 1 ATOM 5125 C CE1 . PHE A 1 642 ? -12.956 9.026 38.096 1.00 17.31 ? 642 PHE A CE1 1 ATOM 5126 C CE2 . PHE A 1 642 ? -15.327 8.600 38.321 1.00 14.00 ? 642 PHE A CE2 1 ATOM 5127 C CZ . PHE A 1 642 ? -14.171 9.248 38.762 1.00 16.34 ? 642 PHE A CZ 1 ATOM 5128 N N . ARG A 1 643 ? -14.671 4.088 37.339 1.00 11.16 ? 643 ARG A N 1 ATOM 5129 C CA . ARG A 1 643 ? -14.922 3.584 38.679 1.00 11.33 ? 643 ARG A CA 1 ATOM 5130 C C . ARG A 1 643 ? -13.966 2.458 39.080 1.00 12.43 ? 643 ARG A C 1 ATOM 5131 O O . ARG A 1 643 ? -13.561 2.426 40.225 1.00 13.55 ? 643 ARG A O 1 ATOM 5132 C CB . ARG A 1 643 ? -16.400 3.178 38.920 1.00 12.28 ? 643 ARG A CB 1 ATOM 5133 C CG . ARG A 1 643 ? -17.328 4.384 38.857 1.00 11.48 ? 643 ARG A CG 1 ATOM 5134 C CD . ARG A 1 643 ? -17.047 5.378 39.970 1.00 15.48 ? 643 ARG A CD 1 ATOM 5135 N NE . ARG A 1 643 ? -18.139 6.359 40.094 1.00 20.32 ? 643 ARG A NE 1 ATOM 5136 C CZ . ARG A 1 643 ? -18.108 7.452 40.855 1.00 23.03 ? 643 ARG A CZ 1 ATOM 5137 N NH1 . ARG A 1 643 ? -17.049 7.743 41.605 1.00 24.79 ? 643 ARG A NH1 1 ATOM 5138 N NH2 . ARG A 1 643 ? -19.168 8.250 40.890 1.00 25.32 ? 643 ARG A NH2 1 ATOM 5139 N N . ALA A 1 644 ? -13.563 1.598 38.148 1.00 12.40 ? 644 ALA A N 1 ATOM 5140 C CA . ALA A 1 644 ? -12.561 0.554 38.491 1.00 12.52 ? 644 ALA A CA 1 ATOM 5141 C C . ALA A 1 644 ? -11.238 1.210 38.931 1.00 13.80 ? 644 ALA A C 1 ATOM 5142 O O . ALA A 1 644 ? -10.628 0.821 39.954 1.00 14.18 ? 644 ALA A O 1 ATOM 5143 C CB . ALA A 1 644 ? -12.329 -0.371 37.257 1.00 13.09 ? 644 ALA A CB 1 ATOM 5144 N N . HIS A 1 645 ? -10.801 2.198 38.152 1.00 13.97 ? 645 HIS A N 1 ATOM 5145 C CA . HIS A 1 645 ? -9.545 2.930 38.425 1.00 14.74 ? 645 HIS A CA 1 ATOM 5146 C C . HIS A 1 645 ? -9.592 3.729 39.734 1.00 14.97 ? 645 HIS A C 1 ATOM 5147 O O . HIS A 1 645 ? -8.602 3.784 40.459 1.00 14.05 ? 645 HIS A O 1 ATOM 5148 C CB . HIS A 1 645 ? -9.212 3.858 37.255 1.00 14.84 ? 645 HIS A CB 1 ATOM 5149 C CG . HIS A 1 645 ? -8.056 4.777 37.513 1.00 17.67 ? 645 HIS A CG 1 ATOM 5150 N ND1 . HIS A 1 645 ? -6.753 4.324 37.575 1.00 19.38 ? 645 HIS A ND1 1 ATOM 5151 C CD2 . HIS A 1 645 ? -7.998 6.123 37.686 1.00 21.15 ? 645 HIS A CD2 1 ATOM 5152 C CE1 . HIS A 1 645 ? -5.941 5.348 37.802 1.00 21.65 ? 645 HIS A CE1 1 ATOM 5153 N NE2 . HIS A 1 645 ? -6.668 6.452 37.865 1.00 24.27 ? 645 HIS A NE2 1 ATOM 5154 N N . SER A 1 646 ? -10.712 4.390 40.022 1.00 14.44 ? 646 SER A N 1 ATOM 5155 C CA . SER A 1 646 ? -10.731 5.341 41.129 1.00 15.51 ? 646 SER A CA 1 ATOM 5156 C C . SER A 1 646 ? -11.247 4.747 42.425 1.00 16.99 ? 646 SER A C 1 ATOM 5157 O O . SER A 1 646 ? -10.901 5.206 43.533 1.00 16.69 ? 646 SER A O 1 ATOM 5158 C CB . SER A 1 646 ? -11.549 6.581 40.740 1.00 17.37 ? 646 SER A CB 1 ATOM 5159 O OG . SER A 1 646 ? -12.879 6.208 40.411 1.00 16.71 ? 646 SER A OG 1 ATOM 5160 N N . ARG A 1 647 ? -12.094 3.729 42.289 1.00 15.48 ? 647 ARG A N 1 ATOM 5161 C CA . ARG A 1 647 ? -12.814 3.183 43.425 1.00 17.30 ? 647 ARG A CA 1 ATOM 5162 C C . ARG A 1 647 ? -12.561 1.680 43.606 1.00 16.26 ? 647 ARG A C 1 ATOM 5163 O O . ARG A 1 647 ? -12.644 1.156 44.715 1.00 17.43 ? 647 ARG A O 1 ATOM 5164 C CB . ARG A 1 647 ? -14.322 3.436 43.246 1.00 17.09 ? 647 ARG A CB 1 ATOM 5165 C CG . ARG A 1 647 ? -15.116 3.119 44.502 1.00 20.67 ? 647 ARG A CG 1 ATOM 5166 C CD . ARG A 1 647 ? -16.495 3.790 44.478 1.00 22.28 ? 647 ARG A CD 1 ATOM 5167 N NE . ARG A 1 647 ? -17.358 3.224 43.447 1.00 21.16 ? 647 ARG A NE 1 ATOM 5168 C CZ . ARG A 1 647 ? -18.440 3.838 42.990 1.00 22.29 ? 647 ARG A CZ 1 ATOM 5169 N NH1 . ARG A 1 647 ? -18.768 5.053 43.460 1.00 20.99 ? 647 ARG A NH1 1 ATOM 5170 N NH2 . ARG A 1 647 ? -19.173 3.266 42.044 1.00 22.50 ? 647 ARG A NH2 1 ATOM 5171 N N . GLY A 1 648 ? -12.249 1.008 42.506 1.00 14.86 ? 648 GLY A N 1 ATOM 5172 C CA . GLY A 1 648 ? -11.961 -0.430 42.502 1.00 15.34 ? 648 GLY A CA 1 ATOM 5173 C C . GLY A 1 648 ? -13.127 -1.331 42.114 1.00 16.01 ? 648 GLY A C 1 ATOM 5174 O O . GLY A 1 648 ? -13.059 -2.539 42.328 1.00 16.16 ? 648 GLY A O 1 ATOM 5175 N N . ASP A 1 649 ? -14.204 -0.766 41.558 1.00 16.56 ? 649 ASP A N 1 ATOM 5176 C CA . ASP A 1 649 ? -15.333 -1.592 41.047 1.00 18.00 ? 649 ASP A CA 1 ATOM 5177 C C . ASP A 1 649 ? -14.918 -2.543 39.906 1.00 17.95 ? 649 ASP A C 1 ATOM 5178 O O . ASP A 1 649 ? -13.968 -2.258 39.160 1.00 19.96 ? 649 ASP A O 1 ATOM 5179 C CB . ASP A 1 649 ? -16.455 -0.700 40.461 1.00 18.26 ? 649 ASP A CB 1 ATOM 5180 C CG . ASP A 1 649 ? -17.006 0.321 41.425 1.00 21.99 ? 649 ASP A CG 1 ATOM 5181 O OD1 . ASP A 1 649 ? -16.323 0.734 42.380 1.00 22.91 ? 649 ASP A OD1 1 ATOM 5182 O OD2 . ASP A 1 649 ? -18.181 0.749 41.195 1.00 26.13 ? 649 ASP A OD2 1 ATOM 5183 N N . THR A 1 650 ? -15.634 -3.655 39.722 1.00 15.97 ? 650 THR A N 1 ATOM 5184 C CA . THR A 1 650 ? -15.429 -4.476 38.531 1.00 15.14 ? 650 THR A CA 1 ATOM 5185 C C . THR A 1 650 ? -16.101 -3.795 37.333 1.00 14.45 ? 650 THR A C 1 ATOM 5186 O O . THR A 1 650 ? -17.006 -2.941 37.512 1.00 14.43 ? 650 THR A O 1 ATOM 5187 C CB . THR A 1 650 ? -16.020 -5.911 38.697 1.00 16.08 ? 650 THR A CB 1 ATOM 5188 O OG1 . THR A 1 650 ? -17.412 -5.795 39.036 1.00 15.57 ? 650 THR A OG1 1 ATOM 5189 C CG2 . THR A 1 650 ? -15.296 -6.668 39.802 1.00 16.34 ? 650 THR A CG2 1 ATOM 5190 N N . VAL A 1 651 ? -15.709 -4.216 36.144 1.00 11.39 ? 651 VAL A N 1 ATOM 5191 C CA . VAL A 1 651 ? -16.289 -3.722 34.896 1.00 11.73 ? 651 VAL A CA 1 ATOM 5192 C C . VAL A 1 651 ? -17.186 -4.791 34.279 1.00 12.10 ? 651 VAL A C 1 ATOM 5193 O O . VAL A 1 651 ? -18.394 -4.595 34.244 1.00 12.86 ? 651 VAL A O 1 ATOM 5194 C CB . VAL A 1 651 ? -15.202 -3.244 33.902 1.00 10.35 ? 651 VAL A CB 1 ATOM 5195 C CG1 . VAL A 1 651 ? -15.825 -2.903 32.560 1.00 10.72 ? 651 VAL A CG1 1 ATOM 5196 C CG2 . VAL A 1 651 ? -14.506 -2.051 34.462 1.00 11.41 ? 651 VAL A CG2 1 ATOM 5197 N N . ALA A 1 652 ? -16.611 -5.910 33.807 1.00 13.35 ? 652 ALA A N 1 ATOM 5198 C CA . ALA A 1 652 ? -17.378 -7.157 33.580 1.00 12.87 ? 652 ALA A CA 1 ATOM 5199 C C . ALA A 1 652 ? -17.640 -7.794 34.937 1.00 13.89 ? 652 ALA A C 1 ATOM 5200 O O . ALA A 1 652 ? -16.713 -8.117 35.701 1.00 14.56 ? 652 ALA A O 1 ATOM 5201 C CB . ALA A 1 652 ? -16.610 -8.130 32.656 1.00 12.86 ? 652 ALA A CB 1 ATOM 5202 N N . ARG A 1 653 ? -18.908 -7.988 35.250 1.00 13.92 ? 653 ARG A N 1 ATOM 5203 C CA . ARG A 1 653 ? -19.323 -8.181 36.636 1.00 14.16 ? 653 ARG A CA 1 ATOM 5204 C C . ARG A 1 653 ? -20.214 -9.396 36.691 1.00 12.88 ? 653 ARG A C 1 ATOM 5205 O O . ARG A 1 653 ? -21.060 -9.573 35.791 1.00 12.68 ? 653 ARG A O 1 ATOM 5206 C CB . ARG A 1 653 ? -20.075 -6.936 37.121 1.00 13.90 ? 653 ARG A CB 1 ATOM 5207 C CG . ARG A 1 653 ? -20.411 -6.993 38.605 1.00 14.97 ? 653 ARG A CG 1 ATOM 5208 C CD . ARG A 1 653 ? -21.002 -5.679 39.087 1.00 14.38 ? 653 ARG A CD 1 ATOM 5209 N NE . ARG A 1 653 ? -20.045 -4.562 38.874 1.00 13.28 ? 653 ARG A NE 1 ATOM 5210 C CZ . ARG A 1 653 ? -20.352 -3.298 39.101 1.00 16.74 ? 653 ARG A CZ 1 ATOM 5211 N NH1 . ARG A 1 653 ? -21.551 -2.994 39.587 1.00 11.56 ? 653 ARG A NH1 1 ATOM 5212 N NH2 . ARG A 1 653 ? -19.470 -2.327 38.855 1.00 16.41 ? 653 ARG A NH2 1 ATOM 5213 N N . PRO A 1 654 ? -19.993 -10.291 37.686 1.00 14.25 ? 654 PRO A N 1 ATOM 5214 C CA . PRO A 1 654 ? -20.888 -11.460 37.814 1.00 13.21 ? 654 PRO A CA 1 ATOM 5215 C C . PRO A 1 654 ? -22.290 -11.034 38.212 1.00 12.69 ? 654 PRO A C 1 ATOM 5216 O O . PRO A 1 654 ? -22.455 -10.066 38.916 1.00 13.14 ? 654 PRO A O 1 ATOM 5217 C CB . PRO A 1 654 ? -20.244 -12.277 38.934 1.00 14.17 ? 654 PRO A CB 1 ATOM 5218 C CG . PRO A 1 654 ? -18.701 -11.767 38.961 1.00 13.77 ? 654 PRO A CG 1 ATOM 5219 C CD . PRO A 1 654 ? -18.878 -10.307 38.677 1.00 12.80 ? 654 PRO A CD 1 ATOM 5220 N N . LEU A 1 655 ? -23.307 -11.758 37.778 1.00 12.35 ? 655 LEU A N 1 ATOM 5221 C CA . LEU A 1 655 ? -24.663 -11.439 38.244 1.00 12.73 ? 655 LEU A CA 1 ATOM 5222 C C . LEU A 1 655 ? -24.779 -11.367 39.745 1.00 12.34 ? 655 LEU A C 1 ATOM 5223 O O . LEU A 1 655 ? -25.472 -10.523 40.263 1.00 13.70 ? 655 LEU A O 1 ATOM 5224 C CB . LEU A 1 655 ? -25.659 -12.486 37.720 1.00 13.52 ? 655 LEU A CB 1 ATOM 5225 C CG . LEU A 1 655 ? -26.300 -12.133 36.375 1.00 14.63 ? 655 LEU A CG 1 ATOM 5226 C CD1 . LEU A 1 655 ? -25.239 -11.990 35.260 1.00 15.55 ? 655 LEU A CD1 1 ATOM 5227 C CD2 . LEU A 1 655 ? -27.363 -13.241 36.048 1.00 14.52 ? 655 LEU A CD2 1 ATOM 5228 N N . LEU A 1 656 ? -24.099 -12.270 40.452 1.00 12.66 ? 656 LEU A N 1 ATOM 5229 C CA . LEU A 1 656 ? -24.156 -12.349 41.910 1.00 13.00 ? 656 LEU A CA 1 ATOM 5230 C C . LEU A 1 656 ? -23.605 -11.112 42.631 1.00 13.11 ? 656 LEU A C 1 ATOM 5231 O O . LEU A 1 656 ? -23.936 -10.897 43.779 1.00 13.01 ? 656 LEU A O 1 ATOM 5232 C CB . LEU A 1 656 ? -23.461 -13.645 42.397 1.00 13.65 ? 656 LEU A CB 1 ATOM 5233 C CG . LEU A 1 656 ? -21.931 -13.584 42.337 1.00 14.46 ? 656 LEU A CG 1 ATOM 5234 C CD1 . LEU A 1 656 ? -21.340 -13.313 43.752 1.00 16.11 ? 656 LEU A CD1 1 ATOM 5235 C CD2 . LEU A 1 656 ? -21.381 -14.901 41.778 1.00 16.35 ? 656 LEU A CD2 1 ATOM 5236 N N . HIS A 1 657 ? -22.774 -10.290 41.979 1.00 13.05 ? 657 HIS A N 1 ATOM 5237 C CA . HIS A 1 657 ? -22.304 -9.076 42.640 1.00 13.17 ? 657 HIS A CA 1 ATOM 5238 C C . HIS A 1 657 ? -23.418 -8.034 42.763 1.00 14.11 ? 657 HIS A C 1 ATOM 5239 O O . HIS A 1 657 ? -23.373 -7.188 43.633 1.00 15.01 ? 657 HIS A O 1 ATOM 5240 C CB . HIS A 1 657 ? -21.128 -8.447 41.887 1.00 13.41 ? 657 HIS A CB 1 ATOM 5241 C CG . HIS A 1 657 ? -19.840 -9.204 42.076 1.00 12.18 ? 657 HIS A CG 1 ATOM 5242 N ND1 . HIS A 1 657 ? -18.614 -8.573 42.129 1.00 12.50 ? 657 HIS A ND1 1 ATOM 5243 C CD2 . HIS A 1 657 ? -19.603 -10.508 42.323 1.00 14.81 ? 657 HIS A CD2 1 ATOM 5244 C CE1 . HIS A 1 657 ? -17.661 -9.476 42.338 1.00 14.63 ? 657 HIS A CE1 1 ATOM 5245 N NE2 . HIS A 1 657 ? -18.232 -10.657 42.463 1.00 13.02 ? 657 HIS A NE2 1 ATOM 5246 N N . GLU A 1 658 ? -24.384 -8.106 41.873 1.00 13.63 ? 658 GLU A N 1 ATOM 5247 C CA . GLU A 1 658 ? -25.556 -7.237 41.989 1.00 14.61 ? 658 GLU A CA 1 ATOM 5248 C C . GLU A 1 658 ? -26.733 -7.938 42.605 1.00 15.05 ? 658 GLU A C 1 ATOM 5249 O O . GLU A 1 658 ? -27.643 -7.277 43.138 1.00 15.78 ? 658 GLU A O 1 ATOM 5250 C CB . GLU A 1 658 ? -25.967 -6.749 40.618 1.00 14.65 ? 658 GLU A CB 1 ATOM 5251 C CG . GLU A 1 658 ? -24.973 -5.741 39.996 1.00 14.64 ? 658 GLU A CG 1 ATOM 5252 C CD . GLU A 1 658 ? -24.789 -4.477 40.793 1.00 19.47 ? 658 GLU A CD 1 ATOM 5253 O OE1 . GLU A 1 658 ? -25.800 -3.850 41.219 1.00 18.37 ? 658 GLU A OE1 1 ATOM 5254 O OE2 . GLU A 1 658 ? -23.608 -4.077 40.962 1.00 16.68 ? 658 GLU A OE2 1 ATOM 5255 N N . PHE A 1 659 ? -26.775 -9.255 42.462 1.00 14.40 ? 659 PHE A N 1 ATOM 5256 C CA . PHE A 1 659 ? -27.998 -10.008 42.833 1.00 15.14 ? 659 PHE A CA 1 ATOM 5257 C C . PHE A 1 659 ? -27.719 -11.119 43.858 1.00 15.74 ? 659 PHE A C 1 ATOM 5258 O O . PHE A 1 659 ? -28.361 -12.194 43.837 1.00 15.08 ? 659 PHE A O 1 ATOM 5259 C CB . PHE A 1 659 ? -28.703 -10.513 41.560 1.00 14.47 ? 659 PHE A CB 1 ATOM 5260 C CG . PHE A 1 659 ? -29.100 -9.411 40.641 1.00 14.14 ? 659 PHE A CG 1 ATOM 5261 C CD1 . PHE A 1 659 ? -30.189 -8.580 40.975 1.00 14.05 ? 659 PHE A CD1 1 ATOM 5262 C CD2 . PHE A 1 659 ? -28.416 -9.190 39.449 1.00 13.40 ? 659 PHE A CD2 1 ATOM 5263 C CE1 . PHE A 1 659 ? -30.573 -7.521 40.112 1.00 13.23 ? 659 PHE A CE1 1 ATOM 5264 C CE2 . PHE A 1 659 ? -28.783 -8.140 38.586 1.00 14.24 ? 659 PHE A CE2 1 ATOM 5265 C CZ . PHE A 1 659 ? -29.910 -7.313 38.932 1.00 13.97 ? 659 PHE A CZ 1 ATOM 5266 N N . TYR A 1 660 ? -26.808 -10.810 44.797 1.00 15.71 ? 660 TYR A N 1 ATOM 5267 C CA . TYR A 1 660 ? -26.319 -11.778 45.847 1.00 16.61 ? 660 TYR A CA 1 ATOM 5268 C C . TYR A 1 660 ? -27.456 -12.279 46.737 1.00 16.64 ? 660 TYR A C 1 ATOM 5269 O O . TYR A 1 660 ? -27.371 -13.360 47.291 1.00 16.76 ? 660 TYR A O 1 ATOM 5270 C CB . TYR A 1 660 ? -25.242 -11.162 46.755 1.00 16.38 ? 660 TYR A CB 1 ATOM 5271 C CG . TYR A 1 660 ? -25.472 -9.730 47.098 1.00 17.47 ? 660 TYR A CG 1 ATOM 5272 C CD1 . TYR A 1 660 ? -26.285 -9.357 48.151 1.00 15.33 ? 660 TYR A CD1 1 ATOM 5273 C CD2 . TYR A 1 660 ? -24.811 -8.704 46.379 1.00 18.19 ? 660 TYR A CD2 1 ATOM 5274 C CE1 . TYR A 1 660 ? -26.498 -8.012 48.449 1.00 17.32 ? 660 TYR A CE1 1 ATOM 5275 C CE2 . TYR A 1 660 ? -25.023 -7.395 46.666 1.00 20.44 ? 660 TYR A CE2 1 ATOM 5276 C CZ . TYR A 1 660 ? -25.873 -7.045 47.694 1.00 19.83 ? 660 TYR A CZ 1 ATOM 5277 O OH . TYR A 1 660 ? -26.055 -5.719 47.951 1.00 21.56 ? 660 TYR A OH 1 ATOM 5278 N N . GLU A 1 661 ? -28.518 -11.486 46.882 1.00 17.50 ? 661 GLU A N 1 ATOM 5279 C CA . GLU A 1 661 ? -29.684 -11.913 47.686 1.00 19.33 ? 661 GLU A CA 1 ATOM 5280 C C . GLU A 1 661 ? -30.395 -13.112 47.081 1.00 17.83 ? 661 GLU A C 1 ATOM 5281 O O . GLU A 1 661 ? -31.131 -13.831 47.774 1.00 18.10 ? 661 GLU A O 1 ATOM 5282 C CB . GLU A 1 661 ? -30.689 -10.737 47.906 1.00 19.32 ? 661 GLU A CB 1 ATOM 5283 C CG . GLU A 1 661 ? -30.104 -9.596 48.772 1.00 23.08 ? 661 GLU A CG 1 ATOM 5284 C CD . GLU A 1 661 ? -31.115 -8.503 49.155 1.00 26.56 ? 661 GLU A CD 1 ATOM 5285 O OE1 . GLU A 1 661 ? -32.324 -8.628 48.795 1.00 35.90 ? 661 GLU A OE1 1 ATOM 5286 O OE2 . GLU A 1 661 ? -30.705 -7.518 49.830 1.00 34.41 ? 661 GLU A OE2 1 ATOM 5287 N N . ASP A 1 662 ? -30.161 -13.337 45.793 1.00 16.79 ? 662 ASP A N 1 ATOM 5288 C CA . ASP A 1 662 ? -30.788 -14.392 45.037 1.00 16.95 ? 662 ASP A CA 1 ATOM 5289 C C . ASP A 1 662 ? -29.850 -15.555 44.769 1.00 17.55 ? 662 ASP A C 1 ATOM 5290 O O . ASP A 1 662 ? -29.050 -15.481 43.839 1.00 16.65 ? 662 ASP A O 1 ATOM 5291 C CB . ASP A 1 662 ? -31.295 -13.781 43.718 1.00 16.62 ? 662 ASP A CB 1 ATOM 5292 C CG . ASP A 1 662 ? -32.065 -14.764 42.842 1.00 17.75 ? 662 ASP A CG 1 ATOM 5293 O OD1 . ASP A 1 662 ? -32.195 -15.971 43.165 1.00 17.60 ? 662 ASP A OD1 1 ATOM 5294 O OD2 . ASP A 1 662 ? -32.545 -14.292 41.794 1.00 18.42 ? 662 ASP A OD2 1 ATOM 5295 N N . ASN A 1 663 ? -29.966 -16.650 45.549 1.00 16.28 ? 663 ASN A N 1 ATOM 5296 C CA . ASN A 1 663 ? -29.075 -17.801 45.362 1.00 17.75 ? 663 ASN A CA 1 ATOM 5297 C C . ASN A 1 663 ? -29.051 -18.426 43.952 1.00 16.46 ? 663 ASN A C 1 ATOM 5298 O O . ASN A 1 663 ? -28.066 -19.103 43.611 1.00 16.18 ? 663 ASN A O 1 ATOM 5299 C CB . ASN A 1 663 ? -29.280 -18.886 46.451 1.00 17.51 ? 663 ASN A CB 1 ATOM 5300 C CG . ASN A 1 663 ? -30.543 -19.669 46.228 1.00 21.99 ? 663 ASN A CG 1 ATOM 5301 O OD1 . ASN A 1 663 ? -31.529 -19.120 45.766 1.00 27.45 ? 663 ASN A OD1 1 ATOM 5302 N ND2 . ASN A 1 663 ? -30.526 -20.958 46.555 1.00 26.98 ? 663 ASN A ND2 1 ATOM 5303 N N . SER A 1 664 ? -30.078 -18.207 43.109 1.00 16.62 ? 664 SER A N 1 ATOM 5304 C CA . SER A 1 664 ? -29.998 -18.681 41.717 1.00 17.58 ? 664 SER A CA 1 ATOM 5305 C C . SER A 1 664 ? -28.901 -17.997 40.875 1.00 17.26 ? 664 SER A C 1 ATOM 5306 O O . SER A 1 664 ? -28.592 -18.471 39.786 1.00 19.49 ? 664 SER A O 1 ATOM 5307 C CB . SER A 1 664 ? -31.338 -18.558 40.959 1.00 18.56 ? 664 SER A CB 1 ATOM 5308 O OG . SER A 1 664 ? -32.332 -19.199 41.692 1.00 20.26 ? 664 SER A OG 1 ATOM 5309 N N . THR A 1 665 ? -28.343 -16.897 41.364 1.00 16.54 ? 665 THR A N 1 ATOM 5310 C CA . THR A 1 665 ? -27.272 -16.206 40.627 1.00 15.33 ? 665 THR A CA 1 ATOM 5311 C C . THR A 1 665 ? -25.875 -16.684 41.035 1.00 16.52 ? 665 THR A C 1 ATOM 5312 O O . THR A 1 665 ? -24.904 -16.322 40.359 1.00 16.15 ? 665 THR A O 1 ATOM 5313 C CB . THR A 1 665 ? -27.316 -14.680 40.787 1.00 16.42 ? 665 THR A CB 1 ATOM 5314 O OG1 . THR A 1 665 ? -27.033 -14.287 42.133 1.00 16.01 ? 665 THR A OG1 1 ATOM 5315 C CG2 . THR A 1 665 ? -28.657 -14.120 40.366 1.00 14.47 ? 665 THR A CG2 1 ATOM 5316 N N . TRP A 1 666 ? -25.773 -17.465 42.121 1.00 15.39 ? 666 TRP A N 1 ATOM 5317 C CA . TRP A 1 666 ? -24.452 -17.753 42.723 1.00 16.15 ? 666 TRP A CA 1 ATOM 5318 C C . TRP A 1 666 ? -23.558 -18.622 41.862 1.00 16.73 ? 666 TRP A C 1 ATOM 5319 O O . TRP A 1 666 ? -22.337 -18.633 42.044 1.00 16.27 ? 666 TRP A O 1 ATOM 5320 C CB . TRP A 1 666 ? -24.568 -18.370 44.126 1.00 16.21 ? 666 TRP A CB 1 ATOM 5321 C CG . TRP A 1 666 ? -25.265 -17.474 45.177 1.00 17.83 ? 666 TRP A CG 1 ATOM 5322 C CD1 . TRP A 1 666 ? -25.596 -16.161 45.058 1.00 15.92 ? 666 TRP A CD1 1 ATOM 5323 C CD2 . TRP A 1 666 ? -25.605 -17.858 46.502 1.00 18.08 ? 666 TRP A CD2 1 ATOM 5324 N NE1 . TRP A 1 666 ? -26.193 -15.702 46.232 1.00 18.97 ? 666 TRP A NE1 1 ATOM 5325 C CE2 . TRP A 1 666 ? -26.206 -16.734 47.133 1.00 18.32 ? 666 TRP A CE2 1 ATOM 5326 C CE3 . TRP A 1 666 ? -25.510 -19.068 47.212 1.00 22.43 ? 666 TRP A CE3 1 ATOM 5327 C CZ2 . TRP A 1 666 ? -26.676 -16.772 48.446 1.00 17.74 ? 666 TRP A CZ2 1 ATOM 5328 C CZ3 . TRP A 1 666 ? -25.978 -19.098 48.555 1.00 19.35 ? 666 TRP A CZ3 1 ATOM 5329 C CH2 . TRP A 1 666 ? -26.564 -17.954 49.134 1.00 19.56 ? 666 TRP A CH2 1 ATOM 5330 N N . ASP A 1 667 ? -24.128 -19.372 40.934 1.00 17.41 ? 667 ASP A N 1 ATOM 5331 C CA . ASP A 1 667 ? -23.226 -20.078 40.036 1.00 20.08 ? 667 ASP A CA 1 ATOM 5332 C C . ASP A 1 667 ? -23.378 -19.694 38.575 1.00 19.54 ? 667 ASP A C 1 ATOM 5333 O O . ASP A 1 667 ? -22.822 -20.360 37.695 1.00 21.33 ? 667 ASP A O 1 ATOM 5334 C CB . ASP A 1 667 ? -23.218 -21.580 40.281 1.00 21.92 ? 667 ASP A CB 1 ATOM 5335 C CG . ASP A 1 667 ? -24.496 -22.229 39.931 1.00 27.81 ? 667 ASP A CG 1 ATOM 5336 O OD1 . ASP A 1 667 ? -25.506 -21.507 39.739 1.00 34.37 ? 667 ASP A OD1 1 ATOM 5337 O OD2 . ASP A 1 667 ? -24.466 -23.474 39.832 1.00 35.14 ? 667 ASP A OD2 1 ATOM 5338 N N . VAL A 1 668 ? -24.065 -18.589 38.314 1.00 17.21 ? 668 VAL A N 1 ATOM 5339 C CA . VAL A 1 668 ? -24.278 -18.161 36.928 1.00 16.90 ? 668 VAL A CA 1 ATOM 5340 C C . VAL A 1 668 ? -22.962 -17.732 36.316 1.00 17.47 ? 668 VAL A C 1 ATOM 5341 O O . VAL A 1 668 ? -22.324 -16.827 36.827 1.00 17.54 ? 668 VAL A O 1 ATOM 5342 C CB . VAL A 1 668 ? -25.334 -17.039 36.810 1.00 16.87 ? 668 VAL A CB 1 ATOM 5343 C CG1 . VAL A 1 668 ? -25.367 -16.482 35.417 1.00 16.98 ? 668 VAL A CG1 1 ATOM 5344 C CG2 . VAL A 1 668 ? -26.688 -17.604 37.165 1.00 17.25 ? 668 VAL A CG2 1 ATOM 5345 N N . HIS A 1 669 ? -22.573 -18.398 35.232 1.00 17.76 ? 669 HIS A N 1 ATOM 5346 C CA . HIS A 1 669 ? -21.305 -18.118 34.555 1.00 19.70 ? 669 HIS A CA 1 ATOM 5347 C C . HIS A 1 669 ? -21.500 -18.090 33.024 1.00 19.85 ? 669 HIS A C 1 ATOM 5348 O O . HIS A 1 669 ? -20.523 -18.012 32.292 1.00 20.01 ? 669 HIS A O 1 ATOM 5349 C CB . HIS A 1 669 ? -20.245 -19.185 34.954 1.00 19.57 ? 669 HIS A CB 1 ATOM 5350 C CG . HIS A 1 669 ? -20.645 -20.590 34.639 1.00 24.29 ? 669 HIS A CG 1 ATOM 5351 N ND1 . HIS A 1 669 ? -20.112 -21.289 33.582 1.00 26.86 ? 669 HIS A ND1 1 ATOM 5352 C CD2 . HIS A 1 669 ? -21.588 -21.397 35.182 1.00 28.90 ? 669 HIS A CD2 1 ATOM 5353 C CE1 . HIS A 1 669 ? -20.672 -22.481 33.513 1.00 29.91 ? 669 HIS A CE1 1 ATOM 5354 N NE2 . HIS A 1 669 ? -21.570 -22.576 34.474 1.00 32.64 ? 669 HIS A NE2 1 ATOM 5355 N N . GLN A 1 670 ? -22.746 -18.181 32.548 1.00 17.88 ? 670 GLN A N 1 ATOM 5356 C CA . GLN A 1 670 ? -23.034 -18.180 31.105 1.00 19.68 ? 670 GLN A CA 1 ATOM 5357 C C . GLN A 1 670 ? -23.649 -16.837 30.678 1.00 18.16 ? 670 GLN A C 1 ATOM 5358 O O . GLN A 1 670 ? -24.049 -16.650 29.518 1.00 17.33 ? 670 GLN A O 1 ATOM 5359 C CB . GLN A 1 670 ? -24.011 -19.324 30.745 1.00 19.99 ? 670 GLN A CB 1 ATOM 5360 C CG . GLN A 1 670 ? -23.358 -20.716 30.545 1.00 24.39 ? 670 GLN A CG 1 ATOM 5361 C CD . GLN A 1 670 ? -24.110 -21.613 29.478 1.00 26.50 ? 670 GLN A CD 1 ATOM 5362 O OE1 . GLN A 1 670 ? -23.536 -22.584 28.931 1.00 31.11 ? 670 GLN A OE1 1 ATOM 5363 N NE2 . GLN A 1 670 ? -25.373 -21.254 29.163 1.00 31.95 ? 670 GLN A NE2 1 ATOM 5364 N N . GLN A 1 671 ? -23.761 -15.939 31.663 1.00 16.12 ? 671 GLN A N 1 ATOM 5365 C CA . GLN A 1 671 ? -24.228 -14.578 31.503 1.00 15.16 ? 671 GLN A CA 1 ATOM 5366 C C . GLN A 1 671 ? -23.312 -13.685 32.338 1.00 14.56 ? 671 GLN A C 1 ATOM 5367 O O . GLN A 1 671 ? -22.674 -14.172 33.269 1.00 15.10 ? 671 GLN A O 1 ATOM 5368 C CB . GLN A 1 671 ? -25.638 -14.458 32.075 1.00 15.74 ? 671 GLN A CB 1 ATOM 5369 C CG . GLN A 1 671 ? -26.744 -15.022 31.174 1.00 17.04 ? 671 GLN A CG 1 ATOM 5370 C CD . GLN A 1 671 ? -28.049 -15.082 31.924 1.00 19.40 ? 671 GLN A CD 1 ATOM 5371 O OE1 . GLN A 1 671 ? -28.230 -15.948 32.769 1.00 19.93 ? 671 GLN A OE1 1 ATOM 5372 N NE2 . GLN A 1 671 ? -28.936 -14.104 31.679 1.00 20.75 ? 671 GLN A NE2 1 ATOM 5373 N N . PHE A 1 672 ? -23.244 -12.403 32.005 1.00 13.79 ? 672 PHE A N 1 ATOM 5374 C CA . PHE A 1 672 ? -22.574 -11.442 32.875 1.00 13.89 ? 672 PHE A CA 1 ATOM 5375 C C . PHE A 1 672 ? -23.144 -10.052 32.677 1.00 14.04 ? 672 PHE A C 1 ATOM 5376 O O . PHE A 1 672 ? -24.025 -9.832 31.804 1.00 13.03 ? 672 PHE A O 1 ATOM 5377 C CB . PHE A 1 672 ? -21.037 -11.501 32.666 1.00 14.22 ? 672 PHE A CB 1 ATOM 5378 C CG . PHE A 1 672 ? -20.585 -11.041 31.316 1.00 15.61 ? 672 PHE A CG 1 ATOM 5379 C CD1 . PHE A 1 672 ? -20.020 -9.777 31.156 1.00 16.97 ? 672 PHE A CD1 1 ATOM 5380 C CD2 . PHE A 1 672 ? -20.663 -11.882 30.213 1.00 16.67 ? 672 PHE A CD2 1 ATOM 5381 C CE1 . PHE A 1 672 ? -19.600 -9.328 29.902 1.00 16.47 ? 672 PHE A CE1 1 ATOM 5382 C CE2 . PHE A 1 672 ? -20.244 -11.448 28.955 1.00 19.43 ? 672 PHE A CE2 1 ATOM 5383 C CZ . PHE A 1 672 ? -19.710 -10.166 28.792 1.00 16.52 ? 672 PHE A CZ 1 ATOM 5384 N N . LEU A 1 673 ? -22.690 -9.112 33.502 1.00 12.98 ? 673 LEU A N 1 ATOM 5385 C CA . LEU A 1 673 ? -23.134 -7.740 33.388 1.00 13.87 ? 673 LEU A CA 1 ATOM 5386 C C . LEU A 1 673 ? -21.987 -6.844 32.944 1.00 14.98 ? 673 LEU A C 1 ATOM 5387 O O . LEU A 1 673 ? -20.822 -7.121 33.265 1.00 14.99 ? 673 LEU A O 1 ATOM 5388 C CB . LEU A 1 673 ? -23.599 -7.245 34.741 1.00 13.07 ? 673 LEU A CB 1 ATOM 5389 C CG . LEU A 1 673 ? -24.528 -8.156 35.531 1.00 14.11 ? 673 LEU A CG 1 ATOM 5390 C CD1 . LEU A 1 673 ? -24.622 -7.633 36.959 1.00 14.82 ? 673 LEU A CD1 1 ATOM 5391 C CD2 . LEU A 1 673 ? -25.899 -8.162 34.884 1.00 16.98 ? 673 LEU A CD2 1 ATOM 5392 N N . TRP A 1 674 ? -22.327 -5.768 32.245 1.00 14.80 ? 674 TRP A N 1 ATOM 5393 C CA . TRP A 1 674 ? -21.458 -4.589 32.272 1.00 15.13 ? 674 TRP A CA 1 ATOM 5394 C C . TRP A 1 674 ? -21.905 -3.722 33.430 1.00 15.55 ? 674 TRP A C 1 ATOM 5395 O O . TRP A 1 674 ? -23.017 -3.136 33.365 1.00 15.33 ? 674 TRP A O 1 ATOM 5396 C CB . TRP A 1 674 ? -21.640 -3.786 30.990 1.00 14.75 ? 674 TRP A CB 1 ATOM 5397 C CG . TRP A 1 674 ? -20.816 -4.178 29.808 1.00 15.06 ? 674 TRP A CG 1 ATOM 5398 C CD1 . TRP A 1 674 ? -20.130 -5.340 29.600 1.00 16.69 ? 674 TRP A CD1 1 ATOM 5399 C CD2 . TRP A 1 674 ? -20.587 -3.355 28.664 1.00 14.72 ? 674 TRP A CD2 1 ATOM 5400 N NE1 . TRP A 1 674 ? -19.481 -5.287 28.373 1.00 18.01 ? 674 TRP A NE1 1 ATOM 5401 C CE2 . TRP A 1 674 ? -19.750 -4.074 27.787 1.00 17.18 ? 674 TRP A CE2 1 ATOM 5402 C CE3 . TRP A 1 674 ? -21.000 -2.057 28.306 1.00 15.64 ? 674 TRP A CE3 1 ATOM 5403 C CZ2 . TRP A 1 674 ? -19.340 -3.555 26.560 1.00 16.87 ? 674 TRP A CZ2 1 ATOM 5404 C CZ3 . TRP A 1 674 ? -20.576 -1.536 27.082 1.00 15.58 ? 674 TRP A CZ3 1 ATOM 5405 C CH2 . TRP A 1 674 ? -19.746 -2.291 26.233 1.00 16.65 ? 674 TRP A CH2 1 ATOM 5406 N N . GLY A 1 675 ? -21.042 -3.560 34.443 1.00 14.35 ? 675 GLY A N 1 ATOM 5407 C CA . GLY A 1 675 ? -21.402 -2.736 35.599 1.00 13.88 ? 675 GLY A CA 1 ATOM 5408 C C . GLY A 1 675 ? -22.703 -3.225 36.258 1.00 13.82 ? 675 GLY A C 1 ATOM 5409 O O . GLY A 1 675 ? -22.939 -4.426 36.317 1.00 12.61 ? 675 GLY A O 1 ATOM 5410 N N . PRO A 1 676 ? -23.505 -2.305 36.786 1.00 14.32 ? 676 PRO A N 1 ATOM 5411 C CA . PRO A 1 676 ? -24.734 -2.755 37.443 1.00 15.92 ? 676 PRO A CA 1 ATOM 5412 C C . PRO A 1 676 ? -25.911 -2.996 36.501 1.00 16.67 ? 676 PRO A C 1 ATOM 5413 O O . PRO A 1 676 ? -26.872 -3.684 36.894 1.00 17.56 ? 676 PRO A O 1 ATOM 5414 C CB . PRO A 1 676 ? -25.044 -1.604 38.394 1.00 15.66 ? 676 PRO A CB 1 ATOM 5415 C CG . PRO A 1 676 ? -24.530 -0.369 37.614 1.00 17.13 ? 676 PRO A CG 1 ATOM 5416 C CD . PRO A 1 676 ? -23.268 -0.852 36.959 1.00 14.03 ? 676 PRO A CD 1 ATOM 5417 N N . GLY A 1 677 ? -25.824 -2.513 35.267 1.00 16.02 ? 677 GLY A N 1 ATOM 5418 C CA . GLY A 1 677 ? -27.055 -2.234 34.512 1.00 16.62 ? 677 GLY A CA 1 ATOM 5419 C C . GLY A 1 677 ? -27.314 -2.980 33.218 1.00 16.48 ? 677 GLY A C 1 ATOM 5420 O O . GLY A 1 677 ? -28.450 -2.992 32.741 1.00 16.44 ? 677 GLY A O 1 ATOM 5421 N N . LEU A 1 678 ? -26.269 -3.538 32.597 1.00 15.51 ? 678 LEU A N 1 ATOM 5422 C CA . LEU A 1 678 ? -26.457 -4.219 31.300 1.00 15.23 ? 678 LEU A CA 1 ATOM 5423 C C . LEU A 1 678 ? -26.242 -5.718 31.444 1.00 15.76 ? 678 LEU A C 1 ATOM 5424 O O . LEU A 1 678 ? -25.162 -6.172 31.812 1.00 15.83 ? 678 LEU A O 1 ATOM 5425 C CB . LEU A 1 678 ? -25.526 -3.631 30.212 1.00 15.64 ? 678 LEU A CB 1 ATOM 5426 C CG . LEU A 1 678 ? -25.446 -4.345 28.847 1.00 14.11 ? 678 LEU A CG 1 ATOM 5427 C CD1 . LEU A 1 678 ? -26.776 -4.081 28.125 1.00 17.74 ? 678 LEU A CD1 1 ATOM 5428 C CD2 . LEU A 1 678 ? -24.330 -3.701 28.043 1.00 15.73 ? 678 LEU A CD2 1 ATOM 5429 N N . LEU A 1 679 ? -27.270 -6.493 31.133 1.00 14.32 ? 679 LEU A N 1 ATOM 5430 C CA . LEU A 1 679 ? -27.215 -7.938 31.220 1.00 14.47 ? 679 LEU A CA 1 ATOM 5431 C C . LEU A 1 679 ? -26.966 -8.529 29.836 1.00 14.38 ? 679 LEU A C 1 ATOM 5432 O O . LEU A 1 679 ? -27.711 -8.274 28.875 1.00 14.15 ? 679 LEU A O 1 ATOM 5433 C CB . LEU A 1 679 ? -28.574 -8.440 31.770 1.00 13.60 ? 679 LEU A CB 1 ATOM 5434 C CG . LEU A 1 679 ? -28.752 -9.942 31.840 1.00 13.57 ? 679 LEU A CG 1 ATOM 5435 C CD1 . LEU A 1 679 ? -27.748 -10.680 32.816 1.00 17.60 ? 679 LEU A CD1 1 ATOM 5436 C CD2 . LEU A 1 679 ? -30.219 -10.284 32.113 1.00 15.63 ? 679 LEU A CD2 1 ATOM 5437 N N . ILE A 1 680 ? -25.897 -9.306 29.725 1.00 13.96 ? 680 ILE A N 1 ATOM 5438 C CA . ILE A 1 680 ? -25.516 -9.916 28.458 1.00 14.36 ? 680 ILE A CA 1 ATOM 5439 C C . ILE A 1 680 ? -25.758 -11.433 28.506 1.00 15.01 ? 680 ILE A C 1 ATOM 5440 O O . ILE A 1 680 ? -25.198 -12.137 29.354 1.00 14.42 ? 680 ILE A O 1 ATOM 5441 C CB . ILE A 1 680 ? -24.014 -9.625 28.128 1.00 14.00 ? 680 ILE A CB 1 ATOM 5442 C CG1 . ILE A 1 680 ? -23.812 -8.113 27.996 1.00 15.36 ? 680 ILE A CG1 1 ATOM 5443 C CG2 . ILE A 1 680 ? -23.607 -10.307 26.797 1.00 15.46 ? 680 ILE A CG2 1 ATOM 5444 C CD1 . ILE A 1 680 ? -22.705 -7.519 28.928 1.00 22.19 ? 680 ILE A CD1 1 ATOM 5445 N N . THR A 1 681 ? -26.541 -11.921 27.545 1.00 14.66 ? 681 THR A N 1 ATOM 5446 C CA . THR A 1 681 ? -26.988 -13.329 27.488 1.00 15.42 ? 681 THR A CA 1 ATOM 5447 C C . THR A 1 681 ? -26.673 -13.921 26.118 1.00 14.81 ? 681 THR A C 1 ATOM 5448 O O . THR A 1 681 ? -27.502 -13.912 25.199 1.00 15.57 ? 681 THR A O 1 ATOM 5449 C CB . THR A 1 681 ? -28.498 -13.462 27.815 1.00 15.99 ? 681 THR A CB 1 ATOM 5450 O OG1 . THR A 1 681 ? -28.768 -12.839 29.066 1.00 18.43 ? 681 THR A OG1 1 ATOM 5451 C CG2 . THR A 1 681 ? -28.936 -14.946 27.921 1.00 17.20 ? 681 THR A CG2 1 ATOM 5452 N N . PRO A 1 682 ? -25.465 -14.493 25.973 1.00 13.18 ? 682 PRO A N 1 ATOM 5453 C CA . PRO A 1 682 ? -25.087 -15.114 24.737 1.00 13.51 ? 682 PRO A CA 1 ATOM 5454 C C . PRO A 1 682 ? -25.610 -16.526 24.491 1.00 14.07 ? 682 PRO A C 1 ATOM 5455 O O . PRO A 1 682 ? -25.843 -17.299 25.424 1.00 14.71 ? 682 PRO A O 1 ATOM 5456 C CB . PRO A 1 682 ? -23.550 -15.228 24.863 1.00 13.30 ? 682 PRO A CB 1 ATOM 5457 C CG . PRO A 1 682 ? -23.342 -15.460 26.344 1.00 12.25 ? 682 PRO A CG 1 ATOM 5458 C CD . PRO A 1 682 ? -24.389 -14.537 26.988 1.00 13.37 ? 682 PRO A CD 1 ATOM 5459 N N . VAL A 1 683 ? -25.731 -16.871 23.211 1.00 15.84 ? 683 VAL A N 1 ATOM 5460 C CA . VAL A 1 683 ? -25.924 -18.264 22.818 1.00 16.78 ? 683 VAL A CA 1 ATOM 5461 C C . VAL A 1 683 ? -24.520 -18.879 22.835 1.00 18.01 ? 683 VAL A C 1 ATOM 5462 O O . VAL A 1 683 ? -23.586 -18.319 22.234 1.00 19.00 ? 683 VAL A O 1 ATOM 5463 C CB . VAL A 1 683 ? -26.590 -18.366 21.414 1.00 16.29 ? 683 VAL A CB 1 ATOM 5464 C CG1 . VAL A 1 683 ? -26.537 -19.831 20.863 1.00 17.37 ? 683 VAL A CG1 1 ATOM 5465 C CG2 . VAL A 1 683 ? -28.038 -17.866 21.492 1.00 16.81 ? 683 VAL A CG2 1 ATOM 5466 N N . LEU A 1 684 ? -24.371 -19.985 23.556 1.00 17.60 ? 684 LEU A N 1 ATOM 5467 C CA . LEU A 1 684 ? -23.049 -20.597 23.772 1.00 20.14 ? 684 LEU A CA 1 ATOM 5468 C C . LEU A 1 684 ? -22.992 -22.064 23.332 1.00 20.91 ? 684 LEU A C 1 ATOM 5469 O O . LEU A 1 684 ? -22.025 -22.770 23.642 1.00 20.90 ? 684 LEU A O 1 ATOM 5470 C CB . LEU A 1 684 ? -22.685 -20.506 25.265 1.00 19.56 ? 684 LEU A CB 1 ATOM 5471 C CG . LEU A 1 684 ? -22.647 -19.090 25.815 1.00 20.01 ? 684 LEU A CG 1 ATOM 5472 C CD1 . LEU A 1 684 ? -22.522 -19.118 27.342 1.00 19.79 ? 684 LEU A CD1 1 ATOM 5473 C CD2 . LEU A 1 684 ? -21.451 -18.393 25.190 1.00 19.16 ? 684 LEU A CD2 1 ATOM 5474 N N . ASP A 1 685 ? -24.033 -22.518 22.633 1.00 22.03 ? 685 ASP A N 1 ATOM 5475 C CA . ASP A 1 685 ? -24.166 -23.931 22.243 1.00 22.82 ? 685 ASP A CA 1 ATOM 5476 C C . ASP A 1 685 ? -24.398 -24.067 20.744 1.00 22.84 ? 685 ASP A C 1 ATOM 5477 O O . ASP A 1 685 ? -25.226 -23.363 20.148 1.00 21.08 ? 685 ASP A O 1 ATOM 5478 C CB . ASP A 1 685 ? -25.294 -24.632 23.014 1.00 24.66 ? 685 ASP A CB 1 ATOM 5479 C CG . ASP A 1 685 ? -24.988 -24.790 24.491 1.00 28.31 ? 685 ASP A CG 1 ATOM 5480 O OD1 . ASP A 1 685 ? -24.114 -25.603 24.857 1.00 35.15 ? 685 ASP A OD1 1 ATOM 5481 O OD2 . ASP A 1 685 ? -25.631 -24.099 25.295 1.00 35.71 ? 685 ASP A OD2 1 ATOM 5482 N N . GLU A 1 686 ? -23.628 -24.971 20.152 1.00 23.01 ? 686 GLU A N 1 ATOM 5483 C CA . GLU A 1 686 ? -23.658 -25.252 18.732 1.00 24.46 ? 686 GLU A CA 1 ATOM 5484 C C . GLU A 1 686 ? -25.060 -25.652 18.302 1.00 24.80 ? 686 GLU A C 1 ATOM 5485 O O . GLU A 1 686 ? -25.680 -26.525 18.932 1.00 24.51 ? 686 GLU A O 1 ATOM 5486 C CB . GLU A 1 686 ? -22.678 -26.375 18.397 1.00 23.61 ? 686 GLU A CB 1 ATOM 5487 C CG . GLU A 1 686 ? -22.436 -26.522 16.904 1.00 25.73 ? 686 GLU A CG 1 ATOM 5488 C CD . GLU A 1 686 ? -21.480 -27.659 16.561 1.00 26.35 ? 686 GLU A CD 1 ATOM 5489 O OE1 . GLU A 1 686 ? -20.781 -28.140 17.462 1.00 29.12 ? 686 GLU A OE1 1 ATOM 5490 O OE2 . GLU A 1 686 ? -21.460 -28.092 15.384 1.00 31.71 ? 686 GLU A OE2 1 ATOM 5491 N N . GLY A 1 687 ? -25.538 -24.999 17.240 1.00 24.46 ? 687 GLY A N 1 ATOM 5492 C CA . GLY A 1 687 ? -26.858 -25.267 16.661 1.00 25.37 ? 687 GLY A CA 1 ATOM 5493 C C . GLY A 1 687 ? -27.987 -24.505 17.314 1.00 25.31 ? 687 GLY A C 1 ATOM 5494 O O . GLY A 1 687 ? -29.100 -24.467 16.783 1.00 25.86 ? 687 GLY A O 1 ATOM 5495 N N . ALA A 1 688 ? -27.712 -23.881 18.462 1.00 24.19 ? 688 ALA A N 1 ATOM 5496 C CA . ALA A 1 688 ? -28.782 -23.265 19.264 1.00 23.62 ? 688 ALA A CA 1 ATOM 5497 C C . ALA A 1 688 ? -29.281 -21.914 18.752 1.00 23.66 ? 688 ALA A C 1 ATOM 5498 O O . ALA A 1 688 ? -28.495 -21.089 18.279 1.00 22.13 ? 688 ALA A O 1 ATOM 5499 C CB . ALA A 1 688 ? -28.377 -23.178 20.754 1.00 23.32 ? 688 ALA A CB 1 ATOM 5500 N N . GLU A 1 689 ? -30.603 -21.722 18.817 1.00 24.35 ? 689 GLU A N 1 ATOM 5501 C CA . GLU A 1 689 ? -31.241 -20.433 18.520 1.00 26.60 ? 689 GLU A CA 1 ATOM 5502 C C . GLU A 1 689 ? -32.070 -19.993 19.741 1.00 25.88 ? 689 GLU A C 1 ATOM 5503 O O . GLU A 1 689 ? -33.022 -19.197 19.662 1.00 24.59 ? 689 GLU A O 1 ATOM 5504 C CB . GLU A 1 689 ? -32.054 -20.475 17.205 1.00 26.71 ? 689 GLU A CB 1 ATOM 5505 C CG . GLU A 1 689 ? -31.185 -20.368 15.926 1.00 29.84 ? 689 GLU A CG 1 ATOM 5506 C CD . GLU A 1 689 ? -31.954 -19.941 14.665 1.00 31.65 ? 689 GLU A CD 1 ATOM 5507 O OE1 . GLU A 1 689 ? -33.008 -20.567 14.400 1.00 36.36 ? 689 GLU A OE1 1 ATOM 5508 O OE2 . GLU A 1 689 ? -31.501 -18.994 13.935 1.00 37.24 ? 689 GLU A OE2 1 ATOM 5509 N N . LYS A 1 690 ? -31.617 -20.480 20.884 1.00 26.45 ? 690 LYS A N 1 ATOM 5510 C CA . LYS A 1 690 ? -32.230 -20.254 22.174 1.00 28.56 ? 690 LYS A CA 1 ATOM 5511 C C . LYS A 1 690 ? -31.126 -20.329 23.197 1.00 28.37 ? 690 LYS A C 1 ATOM 5512 O O . LYS A 1 690 ? -30.067 -20.898 22.935 1.00 29.24 ? 690 LYS A O 1 ATOM 5513 C CB . LYS A 1 690 ? -33.243 -21.357 22.503 1.00 28.92 ? 690 LYS A CB 1 ATOM 5514 C CG . LYS A 1 690 ? -34.583 -21.201 21.818 1.00 33.19 ? 690 LYS A CG 1 ATOM 5515 C CD . LYS A 1 690 ? -35.366 -22.494 21.880 1.00 35.94 ? 690 LYS A CD 1 ATOM 5516 C CE . LYS A 1 690 ? -36.645 -22.412 21.074 1.00 40.98 ? 690 LYS A CE 1 ATOM 5517 N NZ . LYS A 1 690 ? -37.484 -23.638 21.323 1.00 43.23 ? 690 LYS A NZ 1 ATOM 5518 N N . VAL A 1 691 ? -31.360 -19.745 24.362 1.00 28.47 ? 691 VAL A N 1 ATOM 5519 C CA . VAL A 1 691 ? -30.470 -19.973 25.489 1.00 29.28 ? 691 VAL A CA 1 ATOM 5520 C C . VAL A 1 691 ? -31.306 -20.039 26.764 1.00 28.12 ? 691 VAL A C 1 ATOM 5521 O O . VAL A 1 691 ? -32.190 -19.213 26.986 1.00 26.97 ? 691 VAL A O 1 ATOM 5522 C CB . VAL A 1 691 ? -29.354 -18.908 25.576 1.00 28.84 ? 691 VAL A CB 1 ATOM 5523 C CG1 . VAL A 1 691 ? -29.877 -17.626 26.156 1.00 30.81 ? 691 VAL A CG1 1 ATOM 5524 C CG2 . VAL A 1 691 ? -28.200 -19.405 26.444 1.00 33.77 ? 691 VAL A CG2 1 ATOM 5525 N N . MET A 1 692 ? -31.047 -21.069 27.555 1.00 28.18 ? 692 MET A N 1 ATOM 5526 C CA . MET A 1 692 ? -31.589 -21.163 28.899 1.00 28.53 ? 692 MET A CA 1 ATOM 5527 C C . MET A 1 692 ? -30.799 -20.102 29.697 1.00 27.35 ? 692 MET A C 1 ATOM 5528 O O . MET A 1 692 ? -29.584 -20.151 29.770 1.00 27.08 ? 692 MET A O 1 ATOM 5529 C CB . MET A 1 692 ? -31.401 -22.579 29.464 1.00 30.01 ? 692 MET A CB 1 ATOM 5530 C CG . MET A 1 692 ? -32.392 -23.621 28.899 1.00 34.13 ? 692 MET A CG 1 ATOM 5531 S SD . MET A 1 692 ? -34.140 -23.126 29.103 1.00 43.02 ? 692 MET A SD 1 ATOM 5532 C CE . MET A 1 692 ? -35.019 -24.678 28.794 1.00 37.86 ? 692 MET A CE 1 ATOM 5533 N N . ALA A 1 693 ? -31.500 -19.133 30.248 1.00 25.71 ? 693 ALA A N 1 ATOM 5534 C CA . ALA A 1 693 ? -30.850 -17.996 30.903 1.00 24.78 ? 693 ALA A CA 1 ATOM 5535 C C . ALA A 1 693 ? -31.505 -17.717 32.231 1.00 23.46 ? 693 ALA A C 1 ATOM 5536 O O . ALA A 1 693 ? -32.649 -18.099 32.447 1.00 24.50 ? 693 ALA A O 1 ATOM 5537 C CB . ALA A 1 693 ? -30.961 -16.774 30.033 1.00 24.14 ? 693 ALA A CB 1 ATOM 5538 N N . TYR A 1 694 ? -30.795 -17.016 33.107 1.00 21.98 ? 694 TYR A N 1 ATOM 5539 C CA . TYR A 1 694 ? -31.415 -16.499 34.314 1.00 20.11 ? 694 TYR A CA 1 ATOM 5540 C C . TYR A 1 694 ? -31.730 -15.003 34.191 1.00 19.73 ? 694 TYR A C 1 ATOM 5541 O O . TYR A 1 694 ? -30.893 -14.165 33.765 1.00 18.84 ? 694 TYR A O 1 ATOM 5542 C CB . TYR A 1 694 ? -30.600 -16.860 35.585 1.00 21.14 ? 694 TYR A CB 1 ATOM 5543 C CG . TYR A 1 694 ? -31.399 -16.622 36.841 1.00 20.17 ? 694 TYR A CG 1 ATOM 5544 C CD1 . TYR A 1 694 ? -32.488 -17.452 37.163 1.00 21.59 ? 694 TYR A CD1 1 ATOM 5545 C CD2 . TYR A 1 694 ? -31.109 -15.555 37.685 1.00 20.01 ? 694 TYR A CD2 1 ATOM 5546 C CE1 . TYR A 1 694 ? -33.247 -17.219 38.296 1.00 20.36 ? 694 TYR A CE1 1 ATOM 5547 C CE2 . TYR A 1 694 ? -31.850 -15.319 38.831 1.00 19.19 ? 694 TYR A CE2 1 ATOM 5548 C CZ . TYR A 1 694 ? -32.921 -16.172 39.125 1.00 21.56 ? 694 TYR A CZ 1 ATOM 5549 O OH . TYR A 1 694 ? -33.679 -15.945 40.229 1.00 20.21 ? 694 TYR A OH 1 ATOM 5550 N N . VAL A 1 695 ? -32.974 -14.670 34.500 1.00 16.89 ? 695 VAL A N 1 ATOM 5551 C CA . VAL A 1 695 ? -33.386 -13.268 34.595 1.00 17.06 ? 695 VAL A CA 1 ATOM 5552 C C . VAL A 1 695 ? -33.501 -12.863 36.077 1.00 16.97 ? 695 VAL A C 1 ATOM 5553 O O . VAL A 1 695 ? -34.432 -13.283 36.797 1.00 16.28 ? 695 VAL A O 1 ATOM 5554 C CB . VAL A 1 695 ? -34.738 -13.042 33.870 1.00 17.05 ? 695 VAL A CB 1 ATOM 5555 C CG1 . VAL A 1 695 ? -35.168 -11.563 33.994 1.00 14.47 ? 695 VAL A CG1 1 ATOM 5556 C CG2 . VAL A 1 695 ? -34.644 -13.494 32.396 1.00 18.86 ? 695 VAL A CG2 1 ATOM 5557 N N . PRO A 1 696 ? -32.558 -12.032 36.557 1.00 16.06 ? 696 PRO A N 1 ATOM 5558 C CA . PRO A 1 696 ? -32.535 -11.577 37.947 1.00 15.84 ? 696 PRO A CA 1 ATOM 5559 C C . PRO A 1 696 ? -33.759 -10.757 38.413 1.00 16.39 ? 696 PRO A C 1 ATOM 5560 O O . PRO A 1 696 ? -34.608 -10.349 37.594 1.00 17.45 ? 696 PRO A O 1 ATOM 5561 C CB . PRO A 1 696 ? -31.269 -10.710 37.992 1.00 14.93 ? 696 PRO A CB 1 ATOM 5562 C CG . PRO A 1 696 ? -30.394 -11.303 36.873 1.00 15.60 ? 696 PRO A CG 1 ATOM 5563 C CD . PRO A 1 696 ? -31.391 -11.517 35.795 1.00 15.48 ? 696 PRO A CD 1 ATOM 5564 N N . ASP A 1 697 ? -33.820 -10.527 39.726 1.00 16.27 ? 697 ASP A N 1 ATOM 5565 C CA . ASP A 1 697 ? -34.915 -9.798 40.400 1.00 16.68 ? 697 ASP A CA 1 ATOM 5566 C C . ASP A 1 697 ? -34.809 -8.293 40.153 1.00 16.53 ? 697 ASP A C 1 ATOM 5567 O O . ASP A 1 697 ? -34.516 -7.508 41.052 1.00 17.12 ? 697 ASP A O 1 ATOM 5568 C CB . ASP A 1 697 ? -34.903 -10.140 41.892 1.00 16.97 ? 697 ASP A CB 1 ATOM 5569 C CG . ASP A 1 697 ? -36.115 -9.626 42.649 1.00 20.24 ? 697 ASP A CG 1 ATOM 5570 O OD1 . ASP A 1 697 ? -37.091 -9.116 42.033 1.00 20.74 ? 697 ASP A OD1 1 ATOM 5571 O OD2 . ASP A 1 697 ? -36.068 -9.735 43.897 1.00 21.21 ? 697 ASP A OD2 1 ATOM 5572 N N . ALA A 1 698 ? -35.092 -7.890 38.916 1.00 16.53 ? 698 ALA A N 1 ATOM 5573 C CA . ALA A 1 698 ? -35.175 -6.470 38.570 1.00 16.33 ? 698 ALA A CA 1 ATOM 5574 C C . ALA A 1 698 ? -36.196 -6.324 37.474 1.00 15.97 ? 698 ALA A C 1 ATOM 5575 O O . ALA A 1 698 ? -36.587 -7.336 36.861 1.00 15.92 ? 698 ALA A O 1 ATOM 5576 C CB . ALA A 1 698 ? -33.795 -5.965 38.059 1.00 15.53 ? 698 ALA A CB 1 ATOM 5577 N N . VAL A 1 699 ? -36.584 -5.079 37.191 1.00 15.56 ? 699 VAL A N 1 ATOM 5578 C CA . VAL A 1 699 ? -37.282 -4.768 35.928 1.00 16.56 ? 699 VAL A CA 1 ATOM 5579 C C . VAL A 1 699 ? -36.241 -4.842 34.811 1.00 17.14 ? 699 VAL A C 1 ATOM 5580 O O . VAL A 1 699 ? -35.113 -4.336 35.007 1.00 16.83 ? 699 VAL A O 1 ATOM 5581 C CB . VAL A 1 699 ? -37.872 -3.346 35.941 1.00 16.78 ? 699 VAL A CB 1 ATOM 5582 C CG1 . VAL A 1 699 ? -38.475 -3.012 34.566 1.00 18.73 ? 699 VAL A CG1 1 ATOM 5583 C CG2 . VAL A 1 699 ? -38.916 -3.200 37.050 1.00 19.18 ? 699 VAL A CG2 1 ATOM 5584 N N . TRP A 1 700 ? -36.550 -5.514 33.698 1.00 15.96 ? 700 TRP A N 1 ATOM 5585 C CA . TRP A 1 700 ? -35.569 -5.541 32.575 1.00 17.23 ? 700 TRP A CA 1 ATOM 5586 C C . TRP A 1 700 ? -36.207 -5.089 31.269 1.00 17.38 ? 700 TRP A C 1 ATOM 5587 O O . TRP A 1 700 ? -37.384 -5.432 30.985 1.00 17.72 ? 700 TRP A O 1 ATOM 5588 C CB . TRP A 1 700 ? -34.954 -6.932 32.361 1.00 16.28 ? 700 TRP A CB 1 ATOM 5589 C CG . TRP A 1 700 ? -34.179 -7.460 33.515 1.00 17.34 ? 700 TRP A CG 1 ATOM 5590 C CD1 . TRP A 1 700 ? -34.627 -8.267 34.518 1.00 16.30 ? 700 TRP A CD1 1 ATOM 5591 C CD2 . TRP A 1 700 ? -32.792 -7.183 33.801 1.00 15.04 ? 700 TRP A CD2 1 ATOM 5592 N NE1 . TRP A 1 700 ? -33.599 -8.504 35.426 1.00 16.65 ? 700 TRP A NE1 1 ATOM 5593 C CE2 . TRP A 1 700 ? -32.475 -7.837 35.012 1.00 17.60 ? 700 TRP A CE2 1 ATOM 5594 C CE3 . TRP A 1 700 ? -31.815 -6.402 33.167 1.00 15.10 ? 700 TRP A CE3 1 ATOM 5595 C CZ2 . TRP A 1 700 ? -31.186 -7.783 35.590 1.00 16.50 ? 700 TRP A CZ2 1 ATOM 5596 C CZ3 . TRP A 1 700 ? -30.529 -6.326 33.743 1.00 15.60 ? 700 TRP A CZ3 1 ATOM 5597 C CH2 . TRP A 1 700 ? -30.241 -7.003 34.954 1.00 16.99 ? 700 TRP A CH2 1 ATOM 5598 N N . TYR A 1 701 ? -35.427 -4.373 30.450 1.00 15.77 ? 701 TYR A N 1 ATOM 5599 C CA . TYR A 1 701 ? -35.876 -3.920 29.131 1.00 15.26 ? 701 TYR A CA 1 ATOM 5600 C C . TYR A 1 701 ? -35.008 -4.437 28.002 1.00 16.91 ? 701 TYR A C 1 ATOM 5601 O O . TYR A 1 701 ? -33.741 -4.361 28.047 1.00 14.50 ? 701 TYR A O 1 ATOM 5602 C CB . TYR A 1 701 ? -35.883 -2.383 29.090 1.00 15.44 ? 701 TYR A CB 1 ATOM 5603 C CG . TYR A 1 701 ? -36.698 -1.694 30.164 1.00 15.19 ? 701 TYR A CG 1 ATOM 5604 C CD1 . TYR A 1 701 ? -38.060 -1.429 29.960 1.00 17.04 ? 701 TYR A CD1 1 ATOM 5605 C CD2 . TYR A 1 701 ? -36.112 -1.245 31.351 1.00 14.84 ? 701 TYR A CD2 1 ATOM 5606 C CE1 . TYR A 1 701 ? -38.823 -0.781 30.931 1.00 16.32 ? 701 TYR A CE1 1 ATOM 5607 C CE2 . TYR A 1 701 ? -36.892 -0.587 32.350 1.00 15.77 ? 701 TYR A CE2 1 ATOM 5608 C CZ . TYR A 1 701 ? -38.260 -0.365 32.089 1.00 16.13 ? 701 TYR A CZ 1 ATOM 5609 O OH . TYR A 1 701 ? -39.042 0.271 33.018 1.00 15.67 ? 701 TYR A OH 1 ATOM 5610 N N . ASP A 1 702 ? -35.643 -4.968 26.974 1.00 16.49 ? 702 ASP A N 1 ATOM 5611 C CA . ASP A 1 702 ? -34.906 -5.281 25.742 1.00 17.37 ? 702 ASP A CA 1 ATOM 5612 C C . ASP A 1 702 ? -34.131 -4.047 25.208 1.00 17.61 ? 702 ASP A C 1 ATOM 5613 O O . ASP A 1 702 ? -34.679 -2.956 24.997 1.00 16.40 ? 702 ASP A O 1 ATOM 5614 C CB . ASP A 1 702 ? -35.852 -5.873 24.709 1.00 18.78 ? 702 ASP A CB 1 ATOM 5615 C CG . ASP A 1 702 ? -35.162 -6.290 23.465 1.00 21.55 ? 702 ASP A CG 1 ATOM 5616 O OD1 . ASP A 1 702 ? -34.875 -7.488 23.358 1.00 29.54 ? 702 ASP A OD1 1 ATOM 5617 O OD2 . ASP A 1 702 ? -34.887 -5.428 22.605 1.00 24.47 ? 702 ASP A OD2 1 ATOM 5618 N N . TYR A 1 703 ? -32.818 -4.209 25.030 1.00 17.75 ? 703 TYR A N 1 ATOM 5619 C CA . TYR A 1 703 ? -31.994 -3.073 24.660 1.00 19.00 ? 703 TYR A CA 1 ATOM 5620 C C . TYR A 1 703 ? -32.469 -2.435 23.350 1.00 19.44 ? 703 TYR A C 1 ATOM 5621 O O . TYR A 1 703 ? -32.530 -1.209 23.258 1.00 21.60 ? 703 TYR A O 1 ATOM 5622 C CB . TYR A 1 703 ? -30.493 -3.472 24.544 1.00 18.67 ? 703 TYR A CB 1 ATOM 5623 C CG . TYR A 1 703 ? -29.651 -2.313 24.027 1.00 21.31 ? 703 TYR A CG 1 ATOM 5624 C CD1 . TYR A 1 703 ? -29.166 -1.347 24.892 1.00 20.07 ? 703 TYR A CD1 1 ATOM 5625 C CD2 . TYR A 1 703 ? -29.394 -2.164 22.658 1.00 21.65 ? 703 TYR A CD2 1 ATOM 5626 C CE1 . TYR A 1 703 ? -28.426 -0.253 24.417 1.00 20.33 ? 703 TYR A CE1 1 ATOM 5627 C CE2 . TYR A 1 703 ? -28.672 -1.077 22.164 1.00 21.58 ? 703 TYR A CE2 1 ATOM 5628 C CZ . TYR A 1 703 ? -28.191 -0.128 23.059 1.00 21.39 ? 703 TYR A CZ 1 ATOM 5629 O OH . TYR A 1 703 ? -27.481 0.957 22.597 1.00 23.66 ? 703 TYR A OH 1 ATOM 5630 N N . GLU A 1 704 ? -32.766 -3.248 22.342 1.00 19.97 ? 704 GLU A N 1 ATOM 5631 C CA . GLU A 1 704 ? -33.005 -2.709 21.010 1.00 21.13 ? 704 GLU A CA 1 ATOM 5632 C C . GLU A 1 704 ? -34.394 -2.115 20.861 1.00 20.80 ? 704 GLU A C 1 ATOM 5633 O O . GLU A 1 704 ? -34.539 -1.024 20.337 1.00 21.73 ? 704 GLU A O 1 ATOM 5634 C CB . GLU A 1 704 ? -32.747 -3.750 19.944 1.00 21.92 ? 704 GLU A CB 1 ATOM 5635 C CG . GLU A 1 704 ? -31.209 -3.949 19.761 1.00 26.46 ? 704 GLU A CG 1 ATOM 5636 C CD . GLU A 1 704 ? -30.851 -4.471 18.419 1.00 29.68 ? 704 GLU A CD 1 ATOM 5637 O OE1 . GLU A 1 704 ? -31.037 -3.729 17.409 1.00 32.82 ? 704 GLU A OE1 1 ATOM 5638 O OE2 . GLU A 1 704 ? -30.383 -5.624 18.373 1.00 33.91 ? 704 GLU A OE2 1 ATOM 5639 N N . THR A 1 705 ? -35.391 -2.811 21.392 1.00 21.05 ? 705 THR A N 1 ATOM 5640 C CA . THR A 1 705 ? -36.792 -2.312 21.316 1.00 20.60 ? 705 THR A CA 1 ATOM 5641 C C . THR A 1 705 ? -37.178 -1.393 22.477 1.00 20.67 ? 705 THR A C 1 ATOM 5642 O O . THR A 1 705 ? -38.092 -0.544 22.349 1.00 19.37 ? 705 THR A O 1 ATOM 5643 C CB . THR A 1 705 ? -37.789 -3.496 21.246 1.00 21.02 ? 705 THR A CB 1 ATOM 5644 O OG1 . THR A 1 705 ? -37.782 -4.193 22.479 1.00 21.43 ? 705 THR A OG1 1 ATOM 5645 C CG2 . THR A 1 705 ? -37.410 -4.499 20.188 1.00 23.55 ? 705 THR A CG2 1 ATOM 5646 N N . GLY A 1 706 ? -36.522 -1.578 23.632 1.00 17.88 ? 706 GLY A N 1 ATOM 5647 C CA . GLY A 1 706 ? -36.913 -0.910 24.841 1.00 18.16 ? 706 GLY A CA 1 ATOM 5648 C C . GLY A 1 706 ? -38.147 -1.485 25.553 1.00 17.43 ? 706 GLY A C 1 ATOM 5649 O O . GLY A 1 706 ? -38.548 -0.949 26.582 1.00 16.64 ? 706 GLY A O 1 ATOM 5650 N N . SER A 1 707 ? -38.682 -2.603 25.065 1.00 18.64 ? 707 SER A N 1 ATOM 5651 C CA . SER A 1 707 ? -39.856 -3.211 25.711 1.00 20.29 ? 707 SER A CA 1 ATOM 5652 C C . SER A 1 707 ? -39.507 -3.888 27.017 1.00 20.16 ? 707 SER A C 1 ATOM 5653 O O . SER A 1 707 ? -38.472 -4.557 27.135 1.00 18.35 ? 707 SER A O 1 ATOM 5654 C CB . SER A 1 707 ? -40.613 -4.162 24.782 1.00 20.96 ? 707 SER A CB 1 ATOM 5655 O OG . SER A 1 707 ? -39.770 -5.229 24.386 1.00 28.76 ? 707 SER A OG 1 ATOM 5656 N N . GLN A 1 708 ? -40.363 -3.688 28.016 1.00 20.05 ? 708 GLN A N 1 ATOM 5657 C CA . GLN A 1 708 ? -40.155 -4.339 29.308 1.00 21.46 ? 708 GLN A CA 1 ATOM 5658 C C . GLN A 1 708 ? -40.437 -5.843 29.178 1.00 22.45 ? 708 GLN A C 1 ATOM 5659 O O . GLN A 1 708 ? -41.532 -6.246 28.722 1.00 23.36 ? 708 GLN A O 1 ATOM 5660 C CB . GLN A 1 708 ? -41.067 -3.720 30.365 1.00 21.40 ? 708 GLN A CB 1 ATOM 5661 C CG . GLN A 1 708 ? -40.742 -4.207 31.792 1.00 20.28 ? 708 GLN A CG 1 ATOM 5662 C CD . GLN A 1 708 ? -41.662 -3.624 32.850 1.00 23.16 ? 708 GLN A CD 1 ATOM 5663 O OE1 . GLN A 1 708 ? -42.250 -2.568 32.666 1.00 23.96 ? 708 GLN A OE1 1 ATOM 5664 N NE2 . GLN A 1 708 ? -41.746 -4.306 33.999 1.00 25.78 ? 708 GLN A NE2 1 ATOM 5665 N N . VAL A 1 709 ? -39.497 -6.688 29.582 1.00 20.50 ? 709 VAL A N 1 ATOM 5666 C CA . VAL A 1 709 ? -39.752 -8.123 29.545 1.00 21.73 ? 709 VAL A CA 1 ATOM 5667 C C . VAL A 1 709 ? -40.724 -8.517 30.677 1.00 21.69 ? 709 VAL A C 1 ATOM 5668 O O . VAL A 1 709 ? -40.857 -7.814 31.689 1.00 20.29 ? 709 VAL A O 1 ATOM 5669 C CB . VAL A 1 709 ? -38.470 -8.990 29.549 1.00 22.03 ? 709 VAL A CB 1 ATOM 5670 C CG1 . VAL A 1 709 ? -37.540 -8.510 28.468 1.00 22.78 ? 709 VAL A CG1 1 ATOM 5671 C CG2 . VAL A 1 709 ? -37.766 -8.961 30.913 1.00 22.51 ? 709 VAL A CG2 1 ATOM 5672 N N . ARG A 1 710 ? -41.436 -9.617 30.488 1.00 23.38 ? 710 ARG A N 1 ATOM 5673 C CA . ARG A 1 710 ? -42.333 -10.039 31.563 1.00 26.35 ? 710 ARG A CA 1 ATOM 5674 C C . ARG A 1 710 ? -41.560 -10.890 32.589 1.00 26.71 ? 710 ARG A C 1 ATOM 5675 O O . ARG A 1 710 ? -41.964 -11.006 33.746 1.00 28.90 ? 710 ARG A O 1 ATOM 5676 C CB . ARG A 1 710 ? -43.613 -10.684 31.008 1.00 28.53 ? 710 ARG A CB 1 ATOM 5677 C CG . ARG A 1 710 ? -44.547 -9.632 30.331 1.00 32.77 ? 710 ARG A CG 1 ATOM 5678 C CD . ARG A 1 710 ? -44.731 -8.370 31.225 1.00 39.33 ? 710 ARG A CD 1 ATOM 5679 N NE . ARG A 1 710 ? -45.596 -7.325 30.656 1.00 41.04 ? 710 ARG A NE 1 ATOM 5680 C CZ . ARG A 1 710 ? -45.691 -6.085 31.143 1.00 46.12 ? 710 ARG A CZ 1 ATOM 5681 N NH1 . ARG A 1 710 ? -44.979 -5.718 32.212 1.00 46.56 ? 710 ARG A NH1 1 ATOM 5682 N NH2 . ARG A 1 710 ? -46.504 -5.205 30.566 1.00 46.70 ? 710 ARG A NH2 1 ATOM 5683 N N . TRP A 1 711 ? -40.400 -11.396 32.193 1.00 25.48 ? 711 TRP A N 1 ATOM 5684 C CA . TRP A 1 711 ? -39.584 -12.195 33.110 1.00 25.18 ? 711 TRP A CA 1 ATOM 5685 C C . TRP A 1 711 ? -39.037 -11.403 34.292 1.00 23.64 ? 711 TRP A C 1 ATOM 5686 O O . TRP A 1 711 ? -38.521 -10.282 34.124 1.00 23.61 ? 711 TRP A O 1 ATOM 5687 C CB . TRP A 1 711 ? -38.419 -12.848 32.385 1.00 25.95 ? 711 TRP A CB 1 ATOM 5688 C CG . TRP A 1 711 ? -38.708 -13.458 31.043 1.00 27.89 ? 711 TRP A CG 1 ATOM 5689 C CD1 . TRP A 1 711 ? -39.694 -14.360 30.724 1.00 29.12 ? 711 TRP A CD1 1 ATOM 5690 C CD2 . TRP A 1 711 ? -37.949 -13.248 29.850 1.00 27.87 ? 711 TRP A CD2 1 ATOM 5691 N NE1 . TRP A 1 711 ? -39.598 -14.704 29.392 1.00 29.75 ? 711 TRP A NE1 1 ATOM 5692 C CE2 . TRP A 1 711 ? -38.541 -14.030 28.834 1.00 29.21 ? 711 TRP A CE2 1 ATOM 5693 C CE3 . TRP A 1 711 ? -36.845 -12.446 29.533 1.00 27.99 ? 711 TRP A CE3 1 ATOM 5694 C CZ2 . TRP A 1 711 ? -38.053 -14.043 27.523 1.00 29.26 ? 711 TRP A CZ2 1 ATOM 5695 C CZ3 . TRP A 1 711 ? -36.356 -12.465 28.230 1.00 29.69 ? 711 TRP A CZ3 1 ATOM 5696 C CH2 . TRP A 1 711 ? -36.962 -13.255 27.241 1.00 29.17 ? 711 TRP A CH2 1 ATOM 5697 N N . ARG A 1 712 ? -39.110 -12.000 35.481 1.00 22.69 ? 712 ARG A N 1 ATOM 5698 C CA . ARG A 1 712 ? -38.423 -11.457 36.657 1.00 21.59 ? 712 ARG A CA 1 ATOM 5699 C C . ARG A 1 712 ? -38.074 -12.540 37.693 1.00 21.46 ? 712 ARG A C 1 ATOM 5700 O O . ARG A 1 712 ? -38.927 -13.353 38.106 1.00 19.17 ? 712 ARG A O 1 ATOM 5701 C CB . ARG A 1 712 ? -39.209 -10.333 37.303 1.00 22.33 ? 712 ARG A CB 1 ATOM 5702 C CG . ARG A 1 712 ? -38.486 -9.691 38.467 1.00 20.98 ? 712 ARG A CG 1 ATOM 5703 C CD . ARG A 1 712 ? -39.189 -8.432 38.913 1.00 23.87 ? 712 ARG A CD 1 ATOM 5704 N NE . ARG A 1 712 ? -38.448 -7.811 40.001 1.00 26.16 ? 712 ARG A NE 1 ATOM 5705 C CZ . ARG A 1 712 ? -38.559 -6.549 40.372 1.00 27.02 ? 712 ARG A CZ 1 ATOM 5706 N NH1 . ARG A 1 712 ? -39.406 -5.739 39.756 1.00 28.93 ? 712 ARG A NH1 1 ATOM 5707 N NH2 . ARG A 1 712 ? -37.824 -6.108 41.383 1.00 28.78 ? 712 ARG A NH2 1 ATOM 5708 N N . LYS A 1 713 ? -36.802 -12.556 38.098 1.00 19.85 ? 713 LYS A N 1 ATOM 5709 C CA . LYS A 1 713 ? -36.327 -13.544 39.066 1.00 19.72 ? 713 LYS A CA 1 ATOM 5710 C C . LYS A 1 713 ? -36.677 -14.995 38.666 1.00 20.43 ? 713 LYS A C 1 ATOM 5711 O O . LYS A 1 713 ? -37.352 -15.730 39.419 1.00 19.89 ? 713 LYS A O 1 ATOM 5712 C CB . LYS A 1 713 ? -36.846 -13.206 40.477 1.00 19.48 ? 713 LYS A CB 1 ATOM 5713 C CG . LYS A 1 713 ? -35.991 -13.803 41.604 1.00 19.84 ? 713 LYS A CG 1 ATOM 5714 C CD . LYS A 1 713 ? -36.521 -13.415 42.987 1.00 17.40 ? 713 LYS A CD 1 ATOM 5715 C CE . LYS A 1 713 ? -35.600 -13.973 44.085 1.00 20.94 ? 713 LYS A CE 1 ATOM 5716 N NZ . LYS A 1 713 ? -36.038 -13.595 45.472 1.00 23.71 ? 713 LYS A NZ 1 ATOM 5717 N N . GLN A 1 714 ? -36.194 -15.430 37.506 1.00 20.55 ? 714 GLN A N 1 ATOM 5718 C CA . GLN A 1 714 ? -36.580 -16.737 36.988 1.00 21.98 ? 714 GLN A CA 1 ATOM 5719 C C . GLN A 1 714 ? -35.719 -17.212 35.841 1.00 22.21 ? 714 GLN A C 1 ATOM 5720 O O . GLN A 1 714 ? -35.118 -16.391 35.122 1.00 22.19 ? 714 GLN A O 1 ATOM 5721 C CB . GLN A 1 714 ? -38.057 -16.711 36.540 1.00 21.51 ? 714 GLN A CB 1 ATOM 5722 C CG . GLN A 1 714 ? -38.328 -15.839 35.321 1.00 22.20 ? 714 GLN A CG 1 ATOM 5723 C CD . GLN A 1 714 ? -39.807 -15.821 34.972 1.00 23.78 ? 714 GLN A CD 1 ATOM 5724 O OE1 . GLN A 1 714 ? -40.347 -16.836 34.539 1.00 30.11 ? 714 GLN A OE1 1 ATOM 5725 N NE2 . GLN A 1 714 ? -40.465 -14.684 35.177 1.00 22.80 ? 714 GLN A NE2 1 ATOM 5726 N N . LYS A 1 715 ? -35.645 -18.533 35.681 1.00 22.52 ? 715 LYS A N 1 ATOM 5727 C CA . LYS A 1 715 ? -34.938 -19.146 34.556 1.00 25.29 ? 715 LYS A CA 1 ATOM 5728 C C . LYS A 1 715 ? -35.863 -19.042 33.353 1.00 24.95 ? 715 LYS A C 1 ATOM 5729 O O . LYS A 1 715 ? -37.069 -19.235 33.478 1.00 24.97 ? 715 LYS A O 1 ATOM 5730 C CB . LYS A 1 715 ? -34.585 -20.608 34.838 1.00 25.24 ? 715 LYS A CB 1 ATOM 5731 C CG . LYS A 1 715 ? -33.378 -20.805 35.802 1.00 29.51 ? 715 LYS A CG 1 ATOM 5732 C CD . LYS A 1 715 ? -33.376 -22.209 36.463 1.00 28.24 ? 715 LYS A CD 1 ATOM 5733 C CE . LYS A 1 715 ? -32.281 -22.356 37.542 1.00 30.97 ? 715 LYS A CE 1 ATOM 5734 N NZ . LYS A 1 715 ? -32.083 -21.061 38.295 1.00 30.48 ? 715 LYS A NZ 1 ATOM 5735 N N . VAL A 1 716 ? -35.316 -18.684 32.198 1.00 24.56 ? 716 VAL A N 1 ATOM 5736 C CA . VAL A 1 716 ? -36.140 -18.544 30.998 1.00 25.22 ? 716 VAL A CA 1 ATOM 5737 C C . VAL A 1 716 ? -35.466 -19.207 29.818 1.00 25.76 ? 716 VAL A C 1 ATOM 5738 O O . VAL A 1 716 ? -34.244 -19.435 29.819 1.00 26.42 ? 716 VAL A O 1 ATOM 5739 C CB . VAL A 1 716 ? -36.449 -17.053 30.671 1.00 25.19 ? 716 VAL A CB 1 ATOM 5740 C CG1 . VAL A 1 716 ? -37.036 -16.342 31.877 1.00 26.54 ? 716 VAL A CG1 1 ATOM 5741 C CG2 . VAL A 1 716 ? -35.216 -16.319 30.191 1.00 25.75 ? 716 VAL A CG2 1 ATOM 5742 N N . GLU A 1 717 ? -36.249 -19.519 28.797 1.00 25.68 ? 717 GLU A N 1 ATOM 5743 C CA . GLU A 1 717 ? -35.679 -19.893 27.518 1.00 26.58 ? 717 GLU A CA 1 ATOM 5744 C C . GLU A 1 717 ? -35.748 -18.650 26.631 1.00 26.29 ? 717 GLU A C 1 ATOM 5745 O O . GLU A 1 717 ? -36.835 -18.248 26.168 1.00 26.41 ? 717 GLU A O 1 ATOM 5746 C CB . GLU A 1 717 ? -36.454 -21.068 26.916 1.00 27.34 ? 717 GLU A CB 1 ATOM 5747 C CG . GLU A 1 717 ? -35.772 -21.740 25.772 1.00 30.99 ? 717 GLU A CG 1 ATOM 5748 C CD . GLU A 1 717 ? -36.635 -22.824 25.163 1.00 37.56 ? 717 GLU A CD 1 ATOM 5749 O OE1 . GLU A 1 717 ? -36.107 -23.943 24.965 1.00 40.56 ? 717 GLU A OE1 1 ATOM 5750 O OE2 . GLU A 1 717 ? -37.835 -22.548 24.881 1.00 38.27 ? 717 GLU A OE2 1 ATOM 5751 N N . MET A 1 718 ? -34.603 -17.999 26.449 1.00 25.26 ? 718 MET A N 1 ATOM 5752 C CA . MET A 1 718 ? -34.567 -16.763 25.709 1.00 25.60 ? 718 MET A CA 1 ATOM 5753 C C . MET A 1 718 ? -34.409 -17.083 24.225 1.00 25.10 ? 718 MET A C 1 ATOM 5754 O O . MET A 1 718 ? -33.541 -17.859 23.853 1.00 24.21 ? 718 MET A O 1 ATOM 5755 C CB . MET A 1 718 ? -33.399 -15.908 26.205 1.00 25.45 ? 718 MET A CB 1 ATOM 5756 C CG . MET A 1 718 ? -33.627 -14.451 26.059 1.00 28.18 ? 718 MET A CG 1 ATOM 5757 S SD . MET A 1 718 ? -32.187 -13.542 26.681 1.00 26.76 ? 718 MET A SD 1 ATOM 5758 C CE . MET A 1 718 ? -32.475 -13.437 28.426 1.00 22.93 ? 718 MET A CE 1 ATOM 5759 N N . GLU A 1 719 ? -35.273 -16.526 23.385 1.00 24.71 ? 719 GLU A N 1 ATOM 5760 C CA . GLU A 1 719 ? -35.206 -16.841 21.943 1.00 25.09 ? 719 GLU A CA 1 ATOM 5761 C C . GLU A 1 719 ? -34.135 -15.964 21.293 1.00 23.53 ? 719 GLU A C 1 ATOM 5762 O O . GLU A 1 719 ? -34.265 -14.746 21.248 1.00 22.99 ? 719 GLU A O 1 ATOM 5763 C CB . GLU A 1 719 ? -36.548 -16.578 21.263 1.00 25.66 ? 719 GLU A CB 1 ATOM 5764 C CG . GLU A 1 719 ? -37.735 -17.250 21.960 1.00 32.48 ? 719 GLU A CG 1 ATOM 5765 C CD . GLU A 1 719 ? -37.952 -18.688 21.542 1.00 39.56 ? 719 GLU A CD 1 ATOM 5766 O OE1 . GLU A 1 719 ? -37.179 -19.189 20.699 1.00 43.23 ? 719 GLU A OE1 1 ATOM 5767 O OE2 . GLU A 1 719 ? -38.919 -19.318 22.050 1.00 43.42 ? 719 GLU A OE2 1 ATOM 5768 N N . LEU A 1 720 ? -33.072 -16.590 20.816 1.00 23.03 ? 720 LEU A N 1 ATOM 5769 C CA . LEU A 1 720 ? -31.976 -15.847 20.225 1.00 22.61 ? 720 LEU A CA 1 ATOM 5770 C C . LEU A 1 720 ? -31.523 -16.468 18.904 1.00 21.62 ? 720 LEU A C 1 ATOM 5771 O O . LEU A 1 720 ? -30.599 -17.283 18.877 1.00 20.86 ? 720 LEU A O 1 ATOM 5772 C CB . LEU A 1 720 ? -30.814 -15.709 21.214 1.00 22.22 ? 720 LEU A CB 1 ATOM 5773 C CG . LEU A 1 720 ? -31.115 -15.048 22.547 1.00 24.12 ? 720 LEU A CG 1 ATOM 5774 C CD1 . LEU A 1 720 ? -29.953 -15.319 23.510 1.00 24.37 ? 720 LEU A CD1 1 ATOM 5775 C CD2 . LEU A 1 720 ? -31.419 -13.552 22.392 1.00 25.72 ? 720 LEU A CD2 1 ATOM 5776 N N . PRO A 1 721 ? -32.159 -16.054 17.794 1.00 21.52 ? 721 PRO A N 1 ATOM 5777 C CA . PRO A 1 721 ? -31.840 -16.559 16.454 1.00 22.16 ? 721 PRO A CA 1 ATOM 5778 C C . PRO A 1 721 ? -30.380 -16.226 16.089 1.00 21.74 ? 721 PRO A C 1 ATOM 5779 O O . PRO A 1 721 ? -29.707 -15.509 16.840 1.00 22.13 ? 721 PRO A O 1 ATOM 5780 C CB . PRO A 1 721 ? -32.826 -15.824 15.540 1.00 22.66 ? 721 PRO A CB 1 ATOM 5781 C CG . PRO A 1 721 ? -33.858 -15.236 16.431 1.00 22.61 ? 721 PRO A CG 1 ATOM 5782 C CD . PRO A 1 721 ? -33.230 -15.047 17.778 1.00 22.13 ? 721 PRO A CD 1 ATOM 5783 N N . GLY A 1 722 ? -29.888 -16.754 14.975 1.00 20.90 ? 722 GLY A N 1 ATOM 5784 C CA . GLY A 1 722 ? -28.464 -16.597 14.597 1.00 20.90 ? 722 GLY A CA 1 ATOM 5785 C C . GLY A 1 722 ? -27.916 -15.183 14.566 1.00 20.30 ? 722 GLY A C 1 ATOM 5786 O O . GLY A 1 722 ? -26.698 -15.000 14.632 1.00 19.89 ? 722 GLY A O 1 ATOM 5787 N N . ASP A 1 723 ? -28.805 -14.186 14.438 1.00 20.20 ? 723 ASP A N 1 ATOM 5788 C CA . ASP A 1 723 ? -28.424 -12.762 14.405 1.00 20.78 ? 723 ASP A CA 1 ATOM 5789 C C . ASP A 1 723 ? -28.555 -12.011 15.745 1.00 19.45 ? 723 ASP A C 1 ATOM 5790 O O . ASP A 1 723 ? -28.397 -10.796 15.777 1.00 20.52 ? 723 ASP A O 1 ATOM 5791 C CB . ASP A 1 723 ? -29.196 -11.990 13.310 1.00 21.72 ? 723 ASP A CB 1 ATOM 5792 C CG . ASP A 1 723 ? -30.704 -11.991 13.540 1.00 25.48 ? 723 ASP A CG 1 ATOM 5793 O OD1 . ASP A 1 723 ? -31.193 -12.892 14.254 1.00 25.51 ? 723 ASP A OD1 1 ATOM 5794 O OD2 . ASP A 1 723 ? -31.397 -11.087 12.991 1.00 31.14 ? 723 ASP A OD2 1 ATOM 5795 N N . LYS A 1 724 ? -28.843 -12.720 16.836 1.00 19.83 ? 724 LYS A N 1 ATOM 5796 C CA . LYS A 1 724 ? -29.096 -12.071 18.135 1.00 18.74 ? 724 LYS A CA 1 ATOM 5797 C C . LYS A 1 724 ? -28.224 -12.570 19.285 1.00 17.88 ? 724 LYS A C 1 ATOM 5798 O O . LYS A 1 724 ? -27.873 -13.731 19.327 1.00 18.53 ? 724 LYS A O 1 ATOM 5799 C CB . LYS A 1 724 ? -30.566 -12.243 18.554 1.00 19.66 ? 724 LYS A CB 1 ATOM 5800 C CG . LYS A 1 724 ? -31.564 -11.615 17.597 1.00 19.50 ? 724 LYS A CG 1 ATOM 5801 C CD . LYS A 1 724 ? -31.450 -10.118 17.508 1.00 25.23 ? 724 LYS A CD 1 ATOM 5802 C CE . LYS A 1 724 ? -32.431 -9.564 16.442 1.00 28.25 ? 724 LYS A CE 1 ATOM 5803 N NZ . LYS A 1 724 ? -32.523 -8.073 16.519 1.00 31.17 ? 724 LYS A NZ 1 ATOM 5804 N N . ILE A 1 725 ? -27.899 -11.643 20.194 1.00 16.61 ? 725 ILE A N 1 ATOM 5805 C CA . ILE A 1 725 ? -27.414 -11.935 21.536 1.00 16.68 ? 725 ILE A CA 1 ATOM 5806 C C . ILE A 1 725 ? -28.356 -11.206 22.468 1.00 16.59 ? 725 ILE A C 1 ATOM 5807 O O . ILE A 1 725 ? -28.901 -10.167 22.106 1.00 17.40 ? 725 ILE A O 1 ATOM 5808 C CB . ILE A 1 725 ? -25.920 -11.503 21.741 1.00 15.82 ? 725 ILE A CB 1 ATOM 5809 C CG1 . ILE A 1 725 ? -25.483 -11.688 23.199 1.00 15.82 ? 725 ILE A CG1 1 ATOM 5810 C CG2 . ILE A 1 725 ? -25.696 -10.067 21.311 1.00 16.02 ? 725 ILE A CG2 1 ATOM 5811 C CD1 . ILE A 1 725 ? -23.946 -11.906 23.359 1.00 16.50 ? 725 ILE A CD1 1 ATOM 5812 N N . GLY A 1 726 ? -28.605 -11.764 23.644 1.00 16.58 ? 726 GLY A N 1 ATOM 5813 C CA . GLY A 1 726 ? -29.500 -11.088 24.594 1.00 15.99 ? 726 GLY A CA 1 ATOM 5814 C C . GLY A 1 726 ? -28.840 -9.888 25.228 1.00 15.49 ? 726 GLY A C 1 ATOM 5815 O O . GLY A 1 726 ? -27.745 -9.999 25.793 1.00 14.35 ? 726 GLY A O 1 ATOM 5816 N N . LEU A 1 727 ? -29.503 -8.734 25.175 1.00 15.16 ? 727 LEU A N 1 ATOM 5817 C CA . LEU A 1 727 ? -28.972 -7.550 25.841 1.00 15.37 ? 727 LEU A CA 1 ATOM 5818 C C . LEU A 1 727 ? -30.147 -6.918 26.521 1.00 15.67 ? 727 LEU A C 1 ATOM 5819 O O . LEU A 1 727 ? -31.114 -6.544 25.817 1.00 15.10 ? 727 LEU A O 1 ATOM 5820 C CB . LEU A 1 727 ? -28.412 -6.556 24.832 1.00 15.45 ? 727 LEU A CB 1 ATOM 5821 C CG . LEU A 1 727 ? -27.140 -6.969 24.076 1.00 17.49 ? 727 LEU A CG 1 ATOM 5822 C CD1 . LEU A 1 727 ? -26.879 -5.886 23.005 1.00 15.89 ? 727 LEU A CD1 1 ATOM 5823 C CD2 . LEU A 1 727 ? -25.986 -7.108 25.025 1.00 17.30 ? 727 LEU A CD2 1 ATOM 5824 N N . HIS A 1 728 ? -30.087 -6.802 27.854 1.00 14.95 ? 728 HIS A N 1 ATOM 5825 C CA . HIS A 1 728 ? -31.162 -6.160 28.616 1.00 14.80 ? 728 HIS A CA 1 ATOM 5826 C C . HIS A 1 728 ? -30.670 -5.090 29.572 1.00 15.25 ? 728 HIS A C 1 ATOM 5827 O O . HIS A 1 728 ? -29.633 -5.251 30.246 1.00 14.43 ? 728 HIS A O 1 ATOM 5828 C CB . HIS A 1 728 ? -31.925 -7.222 29.393 1.00 15.29 ? 728 HIS A CB 1 ATOM 5829 C CG . HIS A 1 728 ? -32.650 -8.163 28.491 1.00 15.85 ? 728 HIS A CG 1 ATOM 5830 N ND1 . HIS A 1 728 ? -32.048 -9.275 27.950 1.00 15.62 ? 728 HIS A ND1 1 ATOM 5831 C CD2 . HIS A 1 728 ? -33.889 -8.095 27.941 1.00 14.69 ? 728 HIS A CD2 1 ATOM 5832 C CE1 . HIS A 1 728 ? -32.900 -9.891 27.147 1.00 18.34 ? 728 HIS A CE1 1 ATOM 5833 N NE2 . HIS A 1 728 ? -34.024 -9.191 27.123 1.00 18.20 ? 728 HIS A NE2 1 ATOM 5834 N N . LEU A 1 729 ? -31.462 -4.030 29.679 1.00 14.47 ? 729 LEU A N 1 ATOM 5835 C CA . LEU A 1 729 ? -31.176 -2.909 30.541 1.00 14.83 ? 729 LEU A CA 1 ATOM 5836 C C . LEU A 1 729 ? -31.970 -2.980 31.841 1.00 15.43 ? 729 LEU A C 1 ATOM 5837 O O . LEU A 1 729 ? -33.195 -3.187 31.833 1.00 15.61 ? 729 LEU A O 1 ATOM 5838 C CB . LEU A 1 729 ? -31.464 -1.583 29.803 1.00 13.61 ? 729 LEU A CB 1 ATOM 5839 C CG . LEU A 1 729 ? -30.602 -1.301 28.552 1.00 14.14 ? 729 LEU A CG 1 ATOM 5840 C CD1 . LEU A 1 729 ? -31.120 0.019 27.983 1.00 15.22 ? 729 LEU A CD1 1 ATOM 5841 C CD2 . LEU A 1 729 ? -29.150 -1.086 28.965 1.00 15.45 ? 729 LEU A CD2 1 ATOM 5842 N N . ARG A 1 730 ? -31.258 -2.770 32.947 1.00 14.91 ? 730 ARG A N 1 ATOM 5843 C CA . ARG A 1 730 ? -31.838 -2.834 34.283 1.00 14.75 ? 730 ARG A CA 1 ATOM 5844 C C . ARG A 1 730 ? -32.631 -1.602 34.681 1.00 14.76 ? 730 ARG A C 1 ATOM 5845 O O . ARG A 1 730 ? -32.125 -0.483 34.669 1.00 14.56 ? 730 ARG A O 1 ATOM 5846 C CB . ARG A 1 730 ? -30.738 -3.116 35.300 1.00 14.32 ? 730 ARG A CB 1 ATOM 5847 C CG . ARG A 1 730 ? -31.233 -3.347 36.738 1.00 13.90 ? 730 ARG A CG 1 ATOM 5848 C CD . ARG A 1 730 ? -30.048 -3.775 37.560 1.00 15.27 ? 730 ARG A CD 1 ATOM 5849 N NE . ARG A 1 730 ? -30.366 -3.855 38.988 1.00 11.72 ? 730 ARG A NE 1 ATOM 5850 C CZ . ARG A 1 730 ? -29.432 -3.958 39.911 1.00 17.26 ? 730 ARG A CZ 1 ATOM 5851 N NH1 . ARG A 1 730 ? -28.149 -3.987 39.529 1.00 15.17 ? 730 ARG A NH1 1 ATOM 5852 N NH2 . ARG A 1 730 ? -29.751 -4.028 41.191 1.00 15.61 ? 730 ARG A NH2 1 ATOM 5853 N N . GLY A 1 731 ? -33.888 -1.811 35.076 1.00 15.15 ? 731 GLY A N 1 ATOM 5854 C CA . GLY A 1 731 ? -34.675 -0.711 35.596 1.00 14.96 ? 731 GLY A CA 1 ATOM 5855 C C . GLY A 1 731 ? -33.994 -0.104 36.818 1.00 15.49 ? 731 GLY A C 1 ATOM 5856 O O . GLY A 1 731 ? -33.527 -0.824 37.713 1.00 15.93 ? 731 GLY A O 1 ATOM 5857 N N . GLY A 1 732 ? -33.935 1.228 36.856 1.00 14.45 ? 732 GLY A N 1 ATOM 5858 C CA . GLY A 1 732 ? -33.308 1.964 37.970 1.00 14.45 ? 732 GLY A CA 1 ATOM 5859 C C . GLY A 1 732 ? -31.991 2.608 37.568 1.00 14.31 ? 732 GLY A C 1 ATOM 5860 O O . GLY A 1 732 ? -31.363 3.300 38.371 1.00 14.13 ? 732 GLY A O 1 ATOM 5861 N N . TYR A 1 733 ? -31.608 2.381 36.318 1.00 14.31 ? 733 TYR A N 1 ATOM 5862 C CA . TYR A 1 733 ? -30.331 2.876 35.790 1.00 14.58 ? 733 TYR A CA 1 ATOM 5863 C C . TYR A 1 733 ? -30.454 3.763 34.550 1.00 14.67 ? 733 TYR A C 1 ATOM 5864 O O . TYR A 1 733 ? -31.380 3.616 33.720 1.00 14.82 ? 733 TYR A O 1 ATOM 5865 C CB . TYR A 1 733 ? -29.348 1.683 35.584 1.00 13.65 ? 733 TYR A CB 1 ATOM 5866 C CG . TYR A 1 733 ? -29.067 1.010 36.891 1.00 17.75 ? 733 TYR A CG 1 ATOM 5867 C CD1 . TYR A 1 733 ? -27.990 1.419 37.684 1.00 18.32 ? 733 TYR A CD1 1 ATOM 5868 C CD2 . TYR A 1 733 ? -29.933 0.020 37.396 1.00 14.85 ? 733 TYR A CD2 1 ATOM 5869 C CE1 . TYR A 1 733 ? -27.756 0.829 38.918 1.00 18.34 ? 733 TYR A CE1 1 ATOM 5870 C CE2 . TYR A 1 733 ? -29.729 -0.540 38.657 1.00 20.68 ? 733 TYR A CE2 1 ATOM 5871 C CZ . TYR A 1 733 ? -28.628 -0.137 39.398 1.00 21.66 ? 733 TYR A CZ 1 ATOM 5872 O OH . TYR A 1 733 ? -28.409 -0.693 40.642 1.00 21.57 ? 733 TYR A OH 1 ATOM 5873 N N . ILE A 1 734 ? -29.530 4.726 34.457 1.00 14.00 ? 734 ILE A N 1 ATOM 5874 C CA . ILE A 1 734 ? -29.504 5.684 33.365 1.00 14.70 ? 734 ILE A CA 1 ATOM 5875 C C . ILE A 1 734 ? -28.166 5.508 32.697 1.00 15.23 ? 734 ILE A C 1 ATOM 5876 O O . ILE A 1 734 ? -27.127 5.494 33.396 1.00 15.86 ? 734 ILE A O 1 ATOM 5877 C CB . ILE A 1 734 ? -29.704 7.141 33.837 1.00 14.31 ? 734 ILE A CB 1 ATOM 5878 C CG1 . ILE A 1 734 ? -31.055 7.259 34.591 1.00 15.25 ? 734 ILE A CG1 1 ATOM 5879 C CG2 . ILE A 1 734 ? -29.631 8.142 32.631 1.00 14.40 ? 734 ILE A CG2 1 ATOM 5880 C CD1 . ILE A 1 734 ? -31.295 8.596 35.262 1.00 14.36 ? 734 ILE A CD1 1 ATOM 5881 N N . PHE A 1 735 ? -28.216 5.281 31.384 1.00 15.34 ? 735 PHE A N 1 ATOM 5882 C CA . PHE A 1 735 ? -27.023 4.878 30.623 1.00 14.18 ? 735 PHE A CA 1 ATOM 5883 C C . PHE A 1 735 ? -26.654 5.976 29.634 1.00 14.21 ? 735 PHE A C 1 ATOM 5884 O O . PHE A 1 735 ? -27.460 6.326 28.773 1.00 14.81 ? 735 PHE A O 1 ATOM 5885 C CB . PHE A 1 735 ? -27.273 3.589 29.849 1.00 14.09 ? 735 PHE A CB 1 ATOM 5886 C CG . PHE A 1 735 ? -27.733 2.439 30.688 1.00 14.45 ? 735 PHE A CG 1 ATOM 5887 C CD1 . PHE A 1 735 ? -26.842 1.443 31.072 1.00 17.18 ? 735 PHE A CD1 1 ATOM 5888 C CD2 . PHE A 1 735 ? -29.083 2.349 31.083 1.00 13.77 ? 735 PHE A CD2 1 ATOM 5889 C CE1 . PHE A 1 735 ? -27.255 0.364 31.861 1.00 17.42 ? 735 PHE A CE1 1 ATOM 5890 C CE2 . PHE A 1 735 ? -29.522 1.290 31.880 1.00 12.91 ? 735 PHE A CE2 1 ATOM 5891 C CZ . PHE A 1 735 ? -28.636 0.282 32.252 1.00 12.75 ? 735 PHE A CZ 1 ATOM 5892 N N . PRO A 1 736 ? -25.432 6.533 29.768 1.00 13.72 ? 736 PRO A N 1 ATOM 5893 C CA . PRO A 1 736 ? -24.983 7.500 28.792 1.00 13.52 ? 736 PRO A CA 1 ATOM 5894 C C . PRO A 1 736 ? -24.520 6.824 27.514 1.00 14.12 ? 736 PRO A C 1 ATOM 5895 O O . PRO A 1 736 ? -23.847 5.757 27.535 1.00 14.72 ? 736 PRO A O 1 ATOM 5896 C CB . PRO A 1 736 ? -23.819 8.247 29.513 1.00 12.53 ? 736 PRO A CB 1 ATOM 5897 C CG . PRO A 1 736 ? -23.220 7.229 30.406 1.00 12.07 ? 736 PRO A CG 1 ATOM 5898 C CD . PRO A 1 736 ? -24.450 6.329 30.856 1.00 10.99 ? 736 PRO A CD 1 ATOM 5899 N N . THR A 1 737 ? -24.863 7.454 26.389 1.00 14.53 ? 737 THR A N 1 ATOM 5900 C CA . THR A 1 737 ? -24.549 6.905 25.064 1.00 14.04 ? 737 THR A CA 1 ATOM 5901 C C . THR A 1 737 ? -24.001 7.979 24.133 1.00 12.45 ? 737 THR A C 1 ATOM 5902 O O . THR A 1 737 ? -24.068 9.159 24.411 1.00 14.09 ? 737 THR A O 1 ATOM 5903 C CB . THR A 1 737 ? -25.789 6.246 24.352 1.00 15.53 ? 737 THR A CB 1 ATOM 5904 O OG1 . THR A 1 737 ? -26.710 7.268 23.987 1.00 16.27 ? 737 THR A OG1 1 ATOM 5905 C CG2 . THR A 1 737 ? -26.499 5.229 25.243 1.00 16.73 ? 737 THR A CG2 1 ATOM 5906 N N . GLN A 1 738 ? -23.392 7.552 23.046 1.00 13.43 ? 738 GLN A N 1 ATOM 5907 C CA . GLN A 1 738 ? -22.854 8.501 22.072 1.00 13.50 ? 738 GLN A CA 1 ATOM 5908 C C . GLN A 1 738 ? -22.985 7.825 20.726 1.00 14.64 ? 738 GLN A C 1 ATOM 5909 O O . GLN A 1 738 ? -22.613 6.671 20.585 1.00 14.47 ? 738 GLN A O 1 ATOM 5910 C CB . GLN A 1 738 ? -21.382 8.818 22.408 1.00 13.78 ? 738 GLN A CB 1 ATOM 5911 C CG . GLN A 1 738 ? -20.759 9.861 21.462 1.00 13.54 ? 738 GLN A CG 1 ATOM 5912 C CD . GLN A 1 738 ? -19.517 10.506 22.077 1.00 16.75 ? 738 GLN A CD 1 ATOM 5913 O OE1 . GLN A 1 738 ? -18.689 9.810 22.629 1.00 15.92 ? 738 GLN A OE1 1 ATOM 5914 N NE2 . GLN A 1 738 ? -19.382 11.826 21.963 1.00 16.27 ? 738 GLN A NE2 1 ATOM 5915 N N . GLN A 1 739 ? -23.542 8.526 19.730 1.00 13.67 ? 739 GLN A N 1 ATOM 5916 C CA . GLN A 1 739 ? -23.694 7.993 18.398 1.00 16.30 ? 739 GLN A CA 1 ATOM 5917 C C . GLN A 1 739 ? -22.371 7.357 17.957 1.00 16.32 ? 739 GLN A C 1 ATOM 5918 O O . GLN A 1 739 ? -21.317 8.009 18.040 1.00 16.63 ? 739 GLN A O 1 ATOM 5919 C CB . GLN A 1 739 ? -24.059 9.113 17.422 1.00 16.38 ? 739 GLN A CB 1 ATOM 5920 C CG . GLN A 1 739 ? -24.284 8.642 15.983 1.00 18.42 ? 739 GLN A CG 1 ATOM 5921 C CD . GLN A 1 739 ? -24.570 9.783 15.022 1.00 20.13 ? 739 GLN A CD 1 ATOM 5922 O OE1 . GLN A 1 739 ? -24.782 10.924 15.447 1.00 22.53 ? 739 GLN A OE1 1 ATOM 5923 N NE2 . GLN A 1 739 ? -24.576 9.476 13.699 1.00 21.10 ? 739 GLN A NE2 1 ATOM 5924 N N . PRO A 1 740 ? -22.437 6.106 17.501 1.00 16.29 ? 740 PRO A N 1 ATOM 5925 C CA . PRO A 1 740 ? -21.218 5.364 17.162 1.00 16.42 ? 740 PRO A CA 1 ATOM 5926 C C . PRO A 1 740 ? -20.622 5.828 15.817 1.00 17.60 ? 740 PRO A C 1 ATOM 5927 O O . PRO A 1 740 ? -21.297 6.430 14.963 1.00 15.57 ? 740 PRO A O 1 ATOM 5928 C CB . PRO A 1 740 ? -21.704 3.918 17.070 1.00 15.56 ? 740 PRO A CB 1 ATOM 5929 C CG . PRO A 1 740 ? -23.122 4.045 16.629 1.00 16.49 ? 740 PRO A CG 1 ATOM 5930 C CD . PRO A 1 740 ? -23.650 5.277 17.323 1.00 14.24 ? 740 PRO A CD 1 ATOM 5931 N N . ASN A 1 741 ? -19.335 5.562 15.650 1.00 17.48 ? 741 ASN A N 1 ATOM 5932 C CA . ASN A 1 741 ? -18.678 5.770 14.374 1.00 18.34 ? 741 ASN A CA 1 ATOM 5933 C C . ASN A 1 741 ? -17.662 4.629 14.330 1.00 18.22 ? 741 ASN A C 1 ATOM 5934 O O . ASN A 1 741 ? -17.517 3.864 15.303 1.00 18.55 ? 741 ASN A O 1 ATOM 5935 C CB . ASN A 1 741 ? -17.990 7.145 14.323 1.00 18.49 ? 741 ASN A CB 1 ATOM 5936 C CG . ASN A 1 741 ? -17.758 7.676 12.858 1.00 21.16 ? 741 ASN A CG 1 ATOM 5937 O OD1 . ASN A 1 741 ? -17.811 6.926 11.881 1.00 22.58 ? 741 ASN A OD1 1 ATOM 5938 N ND2 . ASN A 1 741 ? -17.506 8.978 12.741 1.00 28.27 ? 741 ASN A ND2 1 ATOM 5939 N N . THR A 1 742 ? -16.976 4.496 13.208 1.00 17.60 ? 742 THR A N 1 ATOM 5940 C CA . THR A 1 742 ? -16.102 3.344 12.999 1.00 17.66 ? 742 THR A CA 1 ATOM 5941 C C . THR A 1 742 ? -14.825 3.415 13.836 1.00 16.50 ? 742 THR A C 1 ATOM 5942 O O . THR A 1 742 ? -14.114 2.401 13.952 1.00 17.01 ? 742 THR A O 1 ATOM 5943 C CB . THR A 1 742 ? -15.712 3.191 11.522 1.00 17.25 ? 742 THR A CB 1 ATOM 5944 O OG1 . THR A 1 742 ? -15.039 4.379 11.097 1.00 19.59 ? 742 THR A OG1 1 ATOM 5945 C CG2 . THR A 1 742 ? -16.927 2.908 10.667 1.00 20.10 ? 742 THR A CG2 1 ATOM 5946 N N . THR A 1 743 ? -14.527 4.585 14.387 1.00 16.91 ? 743 THR A N 1 ATOM 5947 C CA . THR A 1 743 ? -13.384 4.764 15.304 1.00 16.96 ? 743 THR A CA 1 ATOM 5948 C C . THR A 1 743 ? -13.812 5.603 16.501 1.00 17.14 ? 743 THR A C 1 ATOM 5949 O O . THR A 1 743 ? -14.771 6.419 16.404 1.00 17.31 ? 743 THR A O 1 ATOM 5950 C CB . THR A 1 743 ? -12.190 5.473 14.598 1.00 17.92 ? 743 THR A CB 1 ATOM 5951 O OG1 . THR A 1 743 ? -12.541 6.824 14.333 1.00 17.53 ? 743 THR A OG1 1 ATOM 5952 C CG2 . THR A 1 743 ? -11.868 4.793 13.261 1.00 17.90 ? 743 THR A CG2 1 ATOM 5953 N N . THR A 1 744 ? -13.132 5.449 17.634 1.00 16.57 ? 744 THR A N 1 ATOM 5954 C CA . THR A 1 744 ? -13.477 6.279 18.792 1.00 17.67 ? 744 THR A CA 1 ATOM 5955 C C . THR A 1 744 ? -12.932 7.707 18.607 1.00 18.48 ? 744 THR A C 1 ATOM 5956 O O . THR A 1 744 ? -13.468 8.653 19.176 1.00 18.92 ? 744 THR A O 1 ATOM 5957 C CB . THR A 1 744 ? -12.939 5.704 20.107 1.00 18.77 ? 744 THR A CB 1 ATOM 5958 O OG1 . THR A 1 744 ? -11.503 5.584 20.016 1.00 16.49 ? 744 THR A OG1 1 ATOM 5959 C CG2 . THR A 1 744 ? -13.547 4.345 20.415 1.00 17.39 ? 744 THR A CG2 1 ATOM 5960 N N . LEU A 1 745 ? -11.885 7.885 17.793 1.00 18.35 ? 745 LEU A N 1 ATOM 5961 C CA . LEU A 1 745 ? -11.413 9.256 17.471 1.00 18.92 ? 745 LEU A CA 1 ATOM 5962 C C . LEU A 1 745 ? -12.617 10.089 16.991 1.00 19.01 ? 745 LEU A C 1 ATOM 5963 O O . LEU A 1 745 ? -12.861 11.210 17.467 1.00 19.57 ? 745 LEU A O 1 ATOM 5964 C CB . LEU A 1 745 ? -10.354 9.225 16.358 1.00 19.90 ? 745 LEU A CB 1 ATOM 5965 C CG . LEU A 1 745 ? -9.751 10.614 16.073 1.00 21.98 ? 745 LEU A CG 1 ATOM 5966 C CD1 . LEU A 1 745 ? -8.922 11.070 17.237 1.00 24.38 ? 745 LEU A CD1 1 ATOM 5967 C CD2 . LEU A 1 745 ? -8.899 10.594 14.825 1.00 26.90 ? 745 LEU A CD2 1 ATOM 5968 N N . ALA A 1 746 ? -13.368 9.508 16.073 1.00 17.85 ? 746 ALA A N 1 ATOM 5969 C CA . ALA A 1 746 ? -14.548 10.147 15.502 1.00 18.91 ? 746 ALA A CA 1 ATOM 5970 C C . ALA A 1 746 ? -15.767 10.093 16.407 1.00 18.59 ? 746 ALA A C 1 ATOM 5971 O O . ALA A 1 746 ? -16.487 11.096 16.500 1.00 19.23 ? 746 ALA A O 1 ATOM 5972 C CB . ALA A 1 746 ? -14.886 9.554 14.159 1.00 18.61 ? 746 ALA A CB 1 ATOM 5973 N N . SER A 1 747 ? -16.019 8.956 17.053 1.00 17.70 ? 747 SER A N 1 ATOM 5974 C CA . SER A 1 747 ? -17.276 8.789 17.831 1.00 17.85 ? 747 SER A CA 1 ATOM 5975 C C . SER A 1 747 ? -17.346 9.761 19.006 1.00 17.16 ? 747 SER A C 1 ATOM 5976 O O . SER A 1 747 ? -18.410 10.262 19.324 1.00 17.90 ? 747 SER A O 1 ATOM 5977 C CB . SER A 1 747 ? -17.464 7.328 18.291 1.00 17.49 ? 747 SER A CB 1 ATOM 5978 O OG . SER A 1 747 ? -16.559 6.995 19.326 1.00 17.15 ? 747 SER A OG 1 ATOM 5979 N N . ARG A 1 748 ? -16.196 10.079 19.605 1.00 16.00 ? 748 ARG A N 1 ATOM 5980 C CA . ARG A 1 748 ? -16.145 10.989 20.737 1.00 16.18 ? 748 ARG A CA 1 ATOM 5981 C C . ARG A 1 748 ? -16.587 12.411 20.379 1.00 15.12 ? 748 ARG A C 1 ATOM 5982 O O . ARG A 1 748 ? -16.839 13.208 21.270 1.00 15.89 ? 748 ARG A O 1 ATOM 5983 C CB . ARG A 1 748 ? -14.725 11.033 21.339 1.00 16.29 ? 748 ARG A CB 1 ATOM 5984 C CG . ARG A 1 748 ? -14.323 9.786 22.120 1.00 16.64 ? 748 ARG A CG 1 ATOM 5985 C CD . ARG A 1 748 ? -12.818 9.858 22.512 1.00 16.38 ? 748 ARG A CD 1 ATOM 5986 N NE . ARG A 1 748 ? -12.524 11.104 23.190 1.00 15.45 ? 748 ARG A NE 1 ATOM 5987 C CZ . ARG A 1 748 ? -12.697 11.307 24.498 1.00 18.81 ? 748 ARG A CZ 1 ATOM 5988 N NH1 . ARG A 1 748 ? -13.152 10.330 25.276 1.00 20.43 ? 748 ARG A NH1 1 ATOM 5989 N NH2 . ARG A 1 748 ? -12.411 12.487 25.033 1.00 17.28 ? 748 ARG A NH2 1 ATOM 5990 N N . LYS A 1 749 ? -16.647 12.737 19.101 1.00 16.48 ? 749 LYS A N 1 ATOM 5991 C CA . LYS A 1 749 ? -17.135 14.064 18.642 1.00 17.81 ? 749 LYS A CA 1 ATOM 5992 C C . LYS A 1 749 ? -18.643 14.041 18.390 1.00 17.78 ? 749 LYS A C 1 ATOM 5993 O O . LYS A 1 749 ? -19.233 15.068 18.031 1.00 19.81 ? 749 LYS A O 1 ATOM 5994 C CB . LYS A 1 749 ? -16.446 14.484 17.337 1.00 18.22 ? 749 LYS A CB 1 ATOM 5995 C CG . LYS A 1 749 ? -14.888 14.554 17.496 1.00 20.69 ? 749 LYS A CG 1 ATOM 5996 C CD . LYS A 1 749 ? -14.220 14.792 16.162 1.00 25.03 ? 749 LYS A CD 1 ATOM 5997 C CE . LYS A 1 749 ? -12.704 14.655 16.340 1.00 27.09 ? 749 LYS A CE 1 ATOM 5998 N NZ . LYS A 1 749 ? -11.942 14.902 15.074 1.00 31.33 ? 749 LYS A NZ 1 ATOM 5999 N N . ASN A 1 750 ? -19.280 12.895 18.562 1.00 17.85 ? 750 ASN A N 1 ATOM 6000 C CA . ASN A 1 750 ? -20.712 12.770 18.190 1.00 17.68 ? 750 ASN A CA 1 ATOM 6001 C C . ASN A 1 750 ? -21.706 13.188 19.317 1.00 17.28 ? 750 ASN A C 1 ATOM 6002 O O . ASN A 1 750 ? -21.344 13.256 20.486 1.00 16.60 ? 750 ASN A O 1 ATOM 6003 C CB . ASN A 1 750 ? -21.049 11.360 17.716 1.00 17.19 ? 750 ASN A CB 1 ATOM 6004 C CG . ASN A 1 750 ? -20.641 11.091 16.276 1.00 20.21 ? 750 ASN A CG 1 ATOM 6005 O OD1 . ASN A 1 750 ? -20.368 12.015 15.495 1.00 20.14 ? 750 ASN A OD1 1 ATOM 6006 N ND2 . ASN A 1 750 ? -20.573 9.817 15.924 1.00 18.43 ? 750 ASN A ND2 1 ATOM 6007 N N . PRO A 1 751 ? -22.961 13.474 18.946 1.00 18.41 ? 751 PRO A N 1 ATOM 6008 C CA . PRO A 1 751 ? -24.014 13.771 19.929 1.00 18.96 ? 751 PRO A CA 1 ATOM 6009 C C . PRO A 1 751 ? -24.164 12.629 20.945 1.00 18.25 ? 751 PRO A C 1 ATOM 6010 O O . PRO A 1 751 ? -23.999 11.458 20.588 1.00 19.32 ? 751 PRO A O 1 ATOM 6011 C CB . PRO A 1 751 ? -25.266 13.829 19.072 1.00 20.08 ? 751 PRO A CB 1 ATOM 6012 C CG . PRO A 1 751 ? -24.777 14.226 17.709 1.00 20.07 ? 751 PRO A CG 1 ATOM 6013 C CD . PRO A 1 751 ? -23.465 13.572 17.556 1.00 18.59 ? 751 PRO A CD 1 ATOM 6014 N N . LEU A 1 752 ? -24.470 12.999 22.181 1.00 17.87 ? 752 LEU A N 1 ATOM 6015 C CA . LEU A 1 752 ? -24.685 12.073 23.276 1.00 17.32 ? 752 LEU A CA 1 ATOM 6016 C C . LEU A 1 752 ? -26.180 11.801 23.453 1.00 17.89 ? 752 LEU A C 1 ATOM 6017 O O . LEU A 1 752 ? -27.012 12.531 22.935 1.00 16.39 ? 752 LEU A O 1 ATOM 6018 C CB . LEU A 1 752 ? -24.114 12.648 24.573 1.00 18.28 ? 752 LEU A CB 1 ATOM 6019 C CG . LEU A 1 752 ? -22.639 13.104 24.435 1.00 20.01 ? 752 LEU A CG 1 ATOM 6020 C CD1 . LEU A 1 752 ? -22.217 13.964 25.606 1.00 22.24 ? 752 LEU A CD1 1 ATOM 6021 C CD2 . LEU A 1 752 ? -21.847 11.878 24.410 1.00 20.85 ? 752 LEU A CD2 1 ATOM 6022 N N . GLY A 1 753 ? -26.479 10.749 24.203 1.00 17.37 ? 753 GLY A N 1 ATOM 6023 C CA . GLY A 1 753 ? -27.880 10.366 24.492 1.00 16.78 ? 753 GLY A CA 1 ATOM 6024 C C . GLY A 1 753 ? -27.914 9.857 25.919 1.00 17.79 ? 753 GLY A C 1 ATOM 6025 O O . GLY A 1 753 ? -26.870 9.584 26.521 1.00 15.48 ? 753 GLY A O 1 ATOM 6026 N N . LEU A 1 754 ? -29.122 9.748 26.468 1.00 17.00 ? 754 LEU A N 1 ATOM 6027 C CA . LEU A 1 754 ? -29.311 9.117 27.737 1.00 17.42 ? 754 LEU A CA 1 ATOM 6028 C C . LEU A 1 754 ? -30.350 8.027 27.522 1.00 17.16 ? 754 LEU A C 1 ATOM 6029 O O . LEU A 1 754 ? -31.338 8.265 26.824 1.00 18.31 ? 754 LEU A O 1 ATOM 6030 C CB . LEU A 1 754 ? -29.806 10.136 28.779 1.00 16.17 ? 754 LEU A CB 1 ATOM 6031 C CG . LEU A 1 754 ? -28.829 11.147 29.363 1.00 19.43 ? 754 LEU A CG 1 ATOM 6032 C CD1 . LEU A 1 754 ? -29.546 12.037 30.374 1.00 20.68 ? 754 LEU A CD1 1 ATOM 6033 C CD2 . LEU A 1 754 ? -27.580 10.406 29.994 1.00 16.95 ? 754 LEU A CD2 1 ATOM 6034 N N . ILE A 1 755 ? -30.135 6.841 28.088 1.00 16.86 ? 755 ILE A N 1 ATOM 6035 C CA . ILE A 1 755 ? -31.235 5.836 28.149 1.00 16.66 ? 755 ILE A CA 1 ATOM 6036 C C . ILE A 1 755 ? -31.650 5.751 29.625 1.00 17.40 ? 755 ILE A C 1 ATOM 6037 O O . ILE A 1 755 ? -30.844 5.384 30.480 1.00 17.17 ? 755 ILE A O 1 ATOM 6038 C CB . ILE A 1 755 ? -30.855 4.425 27.565 1.00 15.87 ? 755 ILE A CB 1 ATOM 6039 C CG1 . ILE A 1 755 ? -30.401 4.500 26.099 1.00 17.37 ? 755 ILE A CG1 1 ATOM 6040 C CG2 . ILE A 1 755 ? -32.018 3.409 27.697 1.00 16.32 ? 755 ILE A CG2 1 ATOM 6041 C CD1 . ILE A 1 755 ? -29.601 3.189 25.637 1.00 18.12 ? 755 ILE A CD1 1 ATOM 6042 N N . ILE A 1 756 ? -32.909 6.102 29.920 1.00 16.38 ? 756 ILE A N 1 ATOM 6043 C CA . ILE A 1 756 ? -33.437 6.070 31.291 1.00 16.23 ? 756 ILE A CA 1 ATOM 6044 C C . ILE A 1 756 ? -34.329 4.806 31.383 1.00 16.95 ? 756 ILE A C 1 ATOM 6045 O O . ILE A 1 756 ? -35.412 4.768 30.789 1.00 17.47 ? 756 ILE A O 1 ATOM 6046 C CB . ILE A 1 756 ? -34.233 7.397 31.615 1.00 15.32 ? 756 ILE A CB 1 ATOM 6047 C CG1 . ILE A 1 756 ? -33.282 8.609 31.552 1.00 15.82 ? 756 ILE A CG1 1 ATOM 6048 C CG2 . ILE A 1 756 ? -34.901 7.344 32.983 1.00 15.00 ? 756 ILE A CG2 1 ATOM 6049 C CD1 . ILE A 1 756 ? -33.972 9.949 31.471 1.00 16.28 ? 756 ILE A CD1 1 ATOM 6050 N N . ALA A 1 757 ? -33.856 3.778 32.079 1.00 17.67 ? 757 ALA A N 1 ATOM 6051 C CA . ALA A 1 757 ? -34.599 2.525 32.261 1.00 17.10 ? 757 ALA A CA 1 ATOM 6052 C C . ALA A 1 757 ? -35.275 2.687 33.623 1.00 17.38 ? 757 ALA A C 1 ATOM 6053 O O . ALA A 1 757 ? -34.652 2.624 34.653 1.00 17.58 ? 757 ALA A O 1 ATOM 6054 C CB . ALA A 1 757 ? -33.662 1.330 32.247 1.00 18.73 ? 757 ALA A CB 1 ATOM 6055 N N . LEU A 1 758 ? -36.569 2.969 33.623 1.00 16.25 ? 758 LEU A N 1 ATOM 6056 C CA . LEU A 1 758 ? -37.268 3.217 34.890 1.00 16.37 ? 758 LEU A CA 1 ATOM 6057 C C . LEU A 1 758 ? -37.472 1.942 35.760 1.00 17.40 ? 758 LEU A C 1 ATOM 6058 O O . LEU A 1 758 ? -37.782 0.861 35.253 1.00 17.02 ? 758 LEU A O 1 ATOM 6059 C CB . LEU A 1 758 ? -38.607 3.923 34.603 1.00 16.07 ? 758 LEU A CB 1 ATOM 6060 C CG . LEU A 1 758 ? -38.599 5.354 34.076 1.00 14.90 ? 758 LEU A CG 1 ATOM 6061 C CD1 . LEU A 1 758 ? -40.088 5.851 33.846 1.00 17.44 ? 758 LEU A CD1 1 ATOM 6062 C CD2 . LEU A 1 758 ? -37.866 6.274 35.012 1.00 18.17 ? 758 LEU A CD2 1 ATOM 6063 N N . ASP A 1 759 ? -37.282 2.075 37.075 1.00 18.71 ? 759 ASP A N 1 ATOM 6064 C CA . ASP A 1 759 ? -37.621 0.982 37.990 1.00 20.60 ? 759 ASP A CA 1 ATOM 6065 C C . ASP A 1 759 ? -39.137 0.977 38.321 1.00 22.52 ? 759 ASP A C 1 ATOM 6066 O O . ASP A 1 759 ? -39.885 1.780 37.750 1.00 21.73 ? 759 ASP A O 1 ATOM 6067 C CB . ASP A 1 759 ? -36.734 1.014 39.245 1.00 20.82 ? 759 ASP A CB 1 ATOM 6068 C CG . ASP A 1 759 ? -37.056 2.146 40.198 1.00 22.79 ? 759 ASP A CG 1 ATOM 6069 O OD1 . ASP A 1 759 ? -38.132 2.796 40.097 1.00 22.45 ? 759 ASP A OD1 1 ATOM 6070 O OD2 . ASP A 1 759 ? -36.203 2.403 41.081 1.00 24.35 ? 759 ASP A OD2 1 ATOM 6071 N N . GLU A 1 760 ? -39.561 0.069 39.218 1.00 24.17 ? 760 GLU A N 1 ATOM 6072 C CA . GLU A 1 760 ? -40.988 -0.102 39.583 1.00 26.79 ? 760 GLU A CA 1 ATOM 6073 C C . GLU A 1 760 ? -41.525 1.175 40.206 1.00 26.73 ? 760 GLU A C 1 ATOM 6074 O O . GLU A 1 760 ? -42.737 1.437 40.184 1.00 27.96 ? 760 GLU A O 1 ATOM 6075 C CB . GLU A 1 760 ? -41.180 -1.259 40.593 1.00 27.99 ? 760 GLU A CB 1 ATOM 6076 C CG . GLU A 1 760 ? -40.396 -2.550 40.322 1.00 32.66 ? 760 GLU A CG 1 ATOM 6077 C CD . GLU A 1 760 ? -38.997 -2.552 40.946 1.00 37.67 ? 760 GLU A CD 1 ATOM 6078 O OE1 . GLU A 1 760 ? -38.808 -3.246 41.968 1.00 42.11 ? 760 GLU A OE1 1 ATOM 6079 O OE2 . GLU A 1 760 ? -38.093 -1.860 40.430 1.00 39.91 ? 760 GLU A OE2 1 ATOM 6080 N N . ASN A 1 761 ? -40.636 1.975 40.795 1.00 25.20 ? 761 ASN A N 1 ATOM 6081 C CA . ASN A 1 761 ? -41.036 3.284 41.328 1.00 24.98 ? 761 ASN A CA 1 ATOM 6082 C C . ASN A 1 761 ? -40.897 4.482 40.358 1.00 23.38 ? 761 ASN A C 1 ATOM 6083 O O . ASN A 1 761 ? -41.128 5.628 40.733 1.00 23.07 ? 761 ASN A O 1 ATOM 6084 C CB . ASN A 1 761 ? -40.344 3.514 42.675 1.00 25.82 ? 761 ASN A CB 1 ATOM 6085 C CG . ASN A 1 761 ? -40.549 2.337 43.642 1.00 29.81 ? 761 ASN A CG 1 ATOM 6086 O OD1 . ASN A 1 761 ? -41.686 1.862 43.852 1.00 32.38 ? 761 ASN A OD1 1 ATOM 6087 N ND2 . ASN A 1 761 ? -39.460 1.844 44.204 1.00 28.56 ? 761 ASN A ND2 1 ATOM 6088 N N . LYS A 1 762 ? -40.561 4.186 39.097 1.00 21.13 ? 762 LYS A N 1 ATOM 6089 C CA . LYS A 1 762 ? -40.420 5.184 38.021 1.00 21.46 ? 762 LYS A CA 1 ATOM 6090 C C . LYS A 1 762 ? -39.275 6.130 38.348 1.00 19.25 ? 762 LYS A C 1 ATOM 6091 O O . LYS A 1 762 ? -39.335 7.333 38.130 1.00 20.12 ? 762 LYS A O 1 ATOM 6092 C CB . LYS A 1 762 ? -41.747 5.908 37.681 1.00 22.67 ? 762 LYS A CB 1 ATOM 6093 C CG . LYS A 1 762 ? -42.886 4.908 37.266 1.00 25.32 ? 762 LYS A CG 1 ATOM 6094 C CD . LYS A 1 762 ? -42.303 3.672 36.571 1.00 26.54 ? 762 LYS A CD 1 ATOM 6095 C CE . LYS A 1 762 ? -43.282 2.783 35.806 1.00 30.28 ? 762 LYS A CE 1 ATOM 6096 N NZ . LYS A 1 762 ? -44.576 2.539 36.496 1.00 31.55 ? 762 LYS A NZ 1 ATOM 6097 N N . GLU A 1 763 ? -38.231 5.549 38.909 1.00 18.46 ? 763 GLU A N 1 ATOM 6098 C CA . GLU A 1 763 ? -37.021 6.300 39.295 1.00 17.24 ? 763 GLU A CA 1 ATOM 6099 C C . GLU A 1 763 ? -35.820 5.650 38.642 1.00 15.98 ? 763 GLU A C 1 ATOM 6100 O O . GLU A 1 763 ? -35.872 4.503 38.266 1.00 15.21 ? 763 GLU A O 1 ATOM 6101 C CB . GLU A 1 763 ? -36.822 6.273 40.803 1.00 18.47 ? 763 GLU A CB 1 ATOM 6102 C CG . GLU A 1 763 ? -37.989 6.885 41.601 1.00 23.04 ? 763 GLU A CG 1 ATOM 6103 C CD . GLU A 1 763 ? -37.682 6.980 43.069 1.00 29.08 ? 763 GLU A CD 1 ATOM 6104 O OE1 . GLU A 1 763 ? -37.166 5.992 43.647 1.00 32.05 ? 763 GLU A OE1 1 ATOM 6105 O OE2 . GLU A 1 763 ? -37.982 8.045 43.647 1.00 33.24 ? 763 GLU A OE2 1 ATOM 6106 N N . ALA A 1 764 ? -34.721 6.393 38.497 1.00 15.37 ? 764 ALA A N 1 ATOM 6107 C CA . ALA A 1 764 ? -33.505 5.774 37.928 1.00 14.62 ? 764 ALA A CA 1 ATOM 6108 C C . ALA A 1 764 ? -32.361 6.682 38.237 1.00 13.45 ? 764 ALA A C 1 ATOM 6109 O O . ALA A 1 764 ? -32.572 7.836 38.525 1.00 13.79 ? 764 ALA A O 1 ATOM 6110 C CB . ALA A 1 764 ? -33.619 5.644 36.409 1.00 15.12 ? 764 ALA A CB 1 ATOM 6111 N N . LYS A 1 765 ? -31.128 6.175 38.188 1.00 13.95 ? 765 LYS A N 1 ATOM 6112 C CA . LYS A 1 765 ? -29.991 7.030 38.549 1.00 13.78 ? 765 LYS A CA 1 ATOM 6113 C C . LYS A 1 765 ? -28.855 6.603 37.630 1.00 13.42 ? 765 LYS A C 1 ATOM 6114 O O . LYS A 1 765 ? -28.818 5.487 37.199 1.00 13.34 ? 765 LYS A O 1 ATOM 6115 C CB . LYS A 1 765 ? -29.539 6.811 40.002 1.00 17.08 ? 765 LYS A CB 1 ATOM 6116 C CG . LYS A 1 765 ? -30.529 7.299 41.067 1.00 23.59 ? 765 LYS A CG 1 ATOM 6117 C CD . LYS A 1 765 ? -30.088 6.817 42.441 1.00 30.61 ? 765 LYS A CD 1 ATOM 6118 C CE . LYS A 1 765 ? -30.736 7.649 43.554 1.00 34.91 ? 765 LYS A CE 1 ATOM 6119 N NZ . LYS A 1 765 ? -30.303 9.077 43.441 1.00 38.92 ? 765 LYS A NZ 1 ATOM 6120 N N . GLY A 1 766 ? -27.952 7.518 37.307 1.00 13.69 ? 766 GLY A N 1 ATOM 6121 C CA . GLY A 1 766 ? -26.803 7.116 36.476 1.00 13.63 ? 766 GLY A CA 1 ATOM 6122 C C . GLY A 1 766 ? -25.706 8.162 36.645 1.00 14.11 ? 766 GLY A C 1 ATOM 6123 O O . GLY A 1 766 ? -25.859 9.123 37.373 1.00 14.71 ? 766 GLY A O 1 ATOM 6124 N N . GLU A 1 767 ? -24.589 7.978 35.958 1.00 14.59 ? 767 GLU A N 1 ATOM 6125 C CA . GLU A 1 767 ? -23.509 8.960 36.012 1.00 14.67 ? 767 GLU A CA 1 ATOM 6126 C C . GLU A 1 767 ? -22.716 8.894 34.695 1.00 14.04 ? 767 GLU A C 1 ATOM 6127 O O . GLU A 1 767 ? -22.859 7.956 33.915 1.00 13.53 ? 767 GLU A O 1 ATOM 6128 C CB . GLU A 1 767 ? -22.626 8.708 37.230 1.00 16.01 ? 767 GLU A CB 1 ATOM 6129 C CG . GLU A 1 767 ? -21.821 7.405 37.122 1.00 19.06 ? 767 GLU A CG 1 ATOM 6130 C CD . GLU A 1 767 ? -21.130 7.026 38.399 1.00 25.85 ? 767 GLU A CD 1 ATOM 6131 O OE1 . GLU A 1 767 ? -21.190 7.824 39.371 1.00 30.61 ? 767 GLU A OE1 1 ATOM 6132 O OE2 . GLU A 1 767 ? -20.509 5.942 38.426 1.00 29.30 ? 767 GLU A OE2 1 ATOM 6133 N N . LEU A 1 768 ? -21.921 9.927 34.434 1.00 14.67 ? 768 LEU A N 1 ATOM 6134 C CA . LEU A 1 768 ? -21.055 9.959 33.260 1.00 14.53 ? 768 LEU A CA 1 ATOM 6135 C C . LEU A 1 768 ? -19.758 10.646 33.657 1.00 14.81 ? 768 LEU A C 1 ATOM 6136 O O . LEU A 1 768 ? -19.775 11.715 34.226 1.00 14.98 ? 768 LEU A O 1 ATOM 6137 C CB . LEU A 1 768 ? -21.692 10.703 32.064 1.00 15.28 ? 768 LEU A CB 1 ATOM 6138 C CG . LEU A 1 768 ? -20.775 11.053 30.868 1.00 15.05 ? 768 LEU A CG 1 ATOM 6139 C CD1 . LEU A 1 768 ? -20.238 9.748 30.188 1.00 16.38 ? 768 LEU A CD1 1 ATOM 6140 C CD2 . LEU A 1 768 ? -21.528 11.870 29.850 1.00 16.04 ? 768 LEU A CD2 1 ATOM 6141 N N . PHE A 1 769 ? -18.659 9.943 33.431 1.00 13.08 ? 769 PHE A N 1 ATOM 6142 C CA . PHE A 1 769 ? -17.299 10.488 33.548 1.00 12.83 ? 769 PHE A CA 1 ATOM 6143 C C . PHE A 1 769 ? -16.863 10.899 32.156 1.00 12.06 ? 769 PHE A C 1 ATOM 6144 O O . PHE A 1 769 ? -17.094 10.178 31.162 1.00 12.27 ? 769 PHE A O 1 ATOM 6145 C CB . PHE A 1 769 ? -16.377 9.374 34.069 1.00 12.86 ? 769 PHE A CB 1 ATOM 6146 C CG . PHE A 1 769 ? -14.935 9.722 34.022 1.00 11.68 ? 769 PHE A CG 1 ATOM 6147 C CD1 . PHE A 1 769 ? -14.378 10.506 35.021 1.00 12.99 ? 769 PHE A CD1 1 ATOM 6148 C CD2 . PHE A 1 769 ? -14.122 9.230 32.986 1.00 13.22 ? 769 PHE A CD2 1 ATOM 6149 C CE1 . PHE A 1 769 ? -12.984 10.802 34.990 1.00 12.38 ? 769 PHE A CE1 1 ATOM 6150 C CE2 . PHE A 1 769 ? -12.743 9.529 32.957 1.00 13.00 ? 769 PHE A CE2 1 ATOM 6151 C CZ . PHE A 1 769 ? -12.203 10.319 33.960 1.00 14.97 ? 769 PHE A CZ 1 ATOM 6152 N N . TRP A 1 770 ? -16.203 12.057 32.036 1.00 14.39 ? 770 TRP A N 1 ATOM 6153 C CA . TRP A 1 770 ? -15.729 12.465 30.718 1.00 14.50 ? 770 TRP A CA 1 ATOM 6154 C C . TRP A 1 770 ? -14.439 13.269 30.902 1.00 15.09 ? 770 TRP A C 1 ATOM 6155 O O . TRP A 1 770 ? -14.388 14.214 31.675 1.00 15.69 ? 770 TRP A O 1 ATOM 6156 C CB . TRP A 1 770 ? -16.743 13.320 29.960 1.00 16.08 ? 770 TRP A CB 1 ATOM 6157 C CG . TRP A 1 770 ? -16.473 13.374 28.466 1.00 14.95 ? 770 TRP A CG 1 ATOM 6158 C CD1 . TRP A 1 770 ? -15.909 14.427 27.758 1.00 16.76 ? 770 TRP A CD1 1 ATOM 6159 C CD2 . TRP A 1 770 ? -16.744 12.347 27.500 1.00 19.15 ? 770 TRP A CD2 1 ATOM 6160 N NE1 . TRP A 1 770 ? -15.823 14.099 26.429 1.00 15.95 ? 770 TRP A NE1 1 ATOM 6161 C CE2 . TRP A 1 770 ? -16.333 12.839 26.238 1.00 17.63 ? 770 TRP A CE2 1 ATOM 6162 C CE3 . TRP A 1 770 ? -17.275 11.045 27.580 1.00 19.52 ? 770 TRP A CE3 1 ATOM 6163 C CZ2 . TRP A 1 770 ? -16.467 12.086 25.051 1.00 19.02 ? 770 TRP A CZ2 1 ATOM 6164 C CZ3 . TRP A 1 770 ? -17.392 10.288 26.390 1.00 20.01 ? 770 TRP A CZ3 1 ATOM 6165 C CH2 . TRP A 1 770 ? -16.997 10.820 25.150 1.00 17.96 ? 770 TRP A CH2 1 ATOM 6166 N N . ASP A 1 771 ? -13.401 12.812 30.240 1.00 14.83 ? 771 ASP A N 1 ATOM 6167 C CA . ASP A 1 771 ? -12.120 13.548 30.222 1.00 14.00 ? 771 ASP A CA 1 ATOM 6168 C C . ASP A 1 771 ? -11.628 13.506 28.791 1.00 14.38 ? 771 ASP A C 1 ATOM 6169 O O . ASP A 1 771 ? -12.388 13.154 27.886 1.00 14.58 ? 771 ASP A O 1 ATOM 6170 C CB . ASP A 1 771 ? -11.146 12.962 31.256 1.00 13.49 ? 771 ASP A CB 1 ATOM 6171 C CG . ASP A 1 771 ? -10.653 11.555 30.911 1.00 12.35 ? 771 ASP A CG 1 ATOM 6172 O OD1 . ASP A 1 771 ? -11.081 10.943 29.918 1.00 14.23 ? 771 ASP A OD1 1 ATOM 6173 O OD2 . ASP A 1 771 ? -9.752 11.095 31.647 1.00 14.71 ? 771 ASP A OD2 1 ATOM 6174 N N . ASP A 1 772 ? -10.351 13.833 28.552 1.00 14.77 ? 772 ASP A N 1 ATOM 6175 C CA . ASP A 1 772 ? -9.863 13.826 27.204 1.00 14.93 ? 772 ASP A CA 1 ATOM 6176 C C . ASP A 1 772 ? -9.529 12.439 26.613 1.00 14.34 ? 772 ASP A C 1 ATOM 6177 O O . ASP A 1 772 ? -9.151 12.358 25.471 1.00 15.10 ? 772 ASP A O 1 ATOM 6178 C CB . ASP A 1 772 ? -8.692 14.853 27.036 1.00 14.86 ? 772 ASP A CB 1 ATOM 6179 C CG . ASP A 1 772 ? -7.352 14.316 27.571 1.00 19.82 ? 772 ASP A CG 1 ATOM 6180 O OD1 . ASP A 1 772 ? -7.301 13.126 27.968 1.00 17.41 ? 772 ASP A OD1 1 ATOM 6181 O OD2 . ASP A 1 772 ? -6.371 15.102 27.646 1.00 18.81 ? 772 ASP A OD2 1 ATOM 6182 N N . GLY A 1 773 ? -9.709 11.360 27.366 1.00 14.31 ? 773 GLY A N 1 ATOM 6183 C CA . GLY A 1 773 ? -9.625 9.988 26.800 1.00 14.32 ? 773 GLY A CA 1 ATOM 6184 C C . GLY A 1 773 ? -8.197 9.481 26.640 1.00 15.79 ? 773 GLY A C 1 ATOM 6185 O O . GLY A 1 773 ? -7.997 8.365 26.203 1.00 14.89 ? 773 GLY A O 1 ATOM 6186 N N . GLU A 1 774 ? -7.203 10.296 26.988 1.00 15.33 ? 774 GLU A N 1 ATOM 6187 C CA . GLU A 1 774 ? -5.819 9.839 26.732 1.00 18.16 ? 774 GLU A CA 1 ATOM 6188 C C . GLU A 1 774 ? -4.706 10.343 27.628 1.00 18.10 ? 774 GLU A C 1 ATOM 6189 O O . GLU A 1 774 ? -3.647 9.687 27.703 1.00 17.57 ? 774 GLU A O 1 ATOM 6190 C CB . GLU A 1 774 ? -5.441 10.085 25.278 1.00 17.86 ? 774 GLU A CB 1 ATOM 6191 C CG . GLU A 1 774 ? -5.510 11.516 24.829 1.00 23.23 ? 774 GLU A CG 1 ATOM 6192 C CD . GLU A 1 774 ? -5.278 11.607 23.340 1.00 30.78 ? 774 GLU A CD 1 ATOM 6193 O OE1 . GLU A 1 774 ? -6.209 11.262 22.589 1.00 34.36 ? 774 GLU A OE1 1 ATOM 6194 O OE2 . GLU A 1 774 ? -4.160 11.990 22.928 1.00 31.77 ? 774 GLU A OE2 1 ATOM 6195 N N . THR A 1 775 ? -4.903 11.487 28.277 1.00 18.74 ? 775 THR A N 1 ATOM 6196 C CA . THR A 1 775 ? -3.821 12.049 29.130 1.00 20.97 ? 775 THR A CA 1 ATOM 6197 C C . THR A 1 775 ? -3.678 11.247 30.413 1.00 21.44 ? 775 THR A C 1 ATOM 6198 O O . THR A 1 775 ? -4.691 10.830 31.011 1.00 19.64 ? 775 THR A O 1 ATOM 6199 C CB . THR A 1 775 ? -4.044 13.551 29.432 1.00 21.18 ? 775 THR A CB 1 ATOM 6200 O OG1 . THR A 1 775 ? -4.089 14.255 28.190 1.00 21.76 ? 775 THR A OG1 1 ATOM 6201 C CG2 . THR A 1 775 ? -2.914 14.106 30.302 1.00 22.29 ? 775 THR A CG2 1 ATOM 6202 N N . LYS A 1 776 ? -2.431 10.961 30.800 1.00 22.08 ? 776 LYS A N 1 ATOM 6203 C CA . LYS A 1 776 ? -2.163 10.202 32.011 1.00 24.69 ? 776 LYS A CA 1 ATOM 6204 C C . LYS A 1 776 ? -2.431 11.096 33.235 1.00 25.62 ? 776 LYS A C 1 ATOM 6205 O O . LYS A 1 776 ? -2.182 12.291 33.192 1.00 25.93 ? 776 LYS A O 1 ATOM 6206 C CB . LYS A 1 776 ? -0.726 9.612 31.995 1.00 26.21 ? 776 LYS A CB 1 ATOM 6207 C CG . LYS A 1 776 ? -0.490 8.447 32.979 1.00 27.56 ? 776 LYS A CG 1 ATOM 6208 C CD . LYS A 1 776 ? 0.884 7.782 32.765 1.00 26.91 ? 776 LYS A CD 1 ATOM 6209 C CE . LYS A 1 776 ? 0.775 6.539 31.887 1.00 29.61 ? 776 LYS A CE 1 ATOM 6210 N NZ . LYS A 1 776 ? 1.951 5.592 31.959 1.00 32.96 ? 776 LYS A NZ 1 ATOM 6211 N N . ASP A 1 777 ? -3.006 10.525 34.292 1.00 26.56 ? 777 ASP A N 1 ATOM 6212 C CA . ASP A 1 777 ? -3.210 11.243 35.571 1.00 27.50 ? 777 ASP A CA 1 ATOM 6213 C C . ASP A 1 777 ? -4.343 12.308 35.556 1.00 26.24 ? 777 ASP A C 1 ATOM 6214 O O . ASP A 1 777 ? -4.384 13.173 36.422 1.00 26.81 ? 777 ASP A O 1 ATOM 6215 C CB . ASP A 1 777 ? -1.900 11.891 36.060 1.00 28.84 ? 777 ASP A CB 1 ATOM 6216 C CG . ASP A 1 777 ? -0.851 10.875 36.509 1.00 33.55 ? 777 ASP A CG 1 ATOM 6217 O OD1 . ASP A 1 777 ? -1.201 9.700 36.788 1.00 37.47 ? 777 ASP A OD1 1 ATOM 6218 O OD2 . ASP A 1 777 ? 0.339 11.270 36.602 1.00 37.39 ? 777 ASP A OD2 1 ATOM 6219 N N . THR A 1 778 ? -5.252 12.252 34.585 1.00 24.70 ? 778 THR A N 1 ATOM 6220 C CA . THR A 1 778 ? -6.360 13.218 34.556 1.00 23.18 ? 778 THR A CA 1 ATOM 6221 C C . THR A 1 778 ? -7.245 13.073 35.788 1.00 22.10 ? 778 THR A C 1 ATOM 6222 O O . THR A 1 778 ? -7.888 14.051 36.209 1.00 22.06 ? 778 THR A O 1 ATOM 6223 C CB . THR A 1 778 ? -7.273 13.070 33.320 1.00 23.18 ? 778 THR A CB 1 ATOM 6224 O OG1 . THR A 1 778 ? -7.786 11.746 33.292 1.00 24.68 ? 778 THR A OG1 1 ATOM 6225 C CG2 . THR A 1 778 ? -6.535 13.356 32.021 1.00 22.19 ? 778 THR A CG2 1 ATOM 6226 N N . VAL A 1 779 ? -7.293 11.866 36.349 1.00 20.62 ? 779 VAL A N 1 ATOM 6227 C CA . VAL A 1 779 ? -8.100 11.606 37.534 1.00 21.72 ? 779 VAL A CA 1 ATOM 6228 C C . VAL A 1 779 ? -7.360 12.109 38.781 1.00 22.39 ? 779 VAL A C 1 ATOM 6229 O O . VAL A 1 779 ? -7.882 12.908 39.563 1.00 21.56 ? 779 VAL A O 1 ATOM 6230 C CB . VAL A 1 779 ? -8.517 10.116 37.630 1.00 21.08 ? 779 VAL A CB 1 ATOM 6231 C CG1 . VAL A 1 779 ? -9.182 9.823 38.942 1.00 22.54 ? 779 VAL A CG1 1 ATOM 6232 C CG2 . VAL A 1 779 ? -9.416 9.731 36.469 1.00 21.75 ? 779 VAL A CG2 1 ATOM 6233 N N . ALA A 1 780 ? -6.113 11.679 38.936 1.00 23.87 ? 780 ALA A N 1 ATOM 6234 C CA . ALA A 1 780 ? -5.287 12.170 40.029 1.00 25.42 ? 780 ALA A CA 1 ATOM 6235 C C . ALA A 1 780 ? -5.141 13.704 40.023 1.00 26.04 ? 780 ALA A C 1 ATOM 6236 O O . ALA A 1 780 ? -5.190 14.335 41.077 1.00 27.04 ? 780 ALA A O 1 ATOM 6237 C CB . ALA A 1 780 ? -3.903 11.460 40.017 1.00 26.10 ? 780 ALA A CB 1 ATOM 6238 N N . ASN A 1 781 ? -5.015 14.316 38.849 1.00 26.88 ? 781 ASN A N 1 ATOM 6239 C CA . ASN A 1 781 ? -4.874 15.774 38.752 1.00 27.86 ? 781 ASN A CA 1 ATOM 6240 C C . ASN A 1 781 ? -6.203 16.524 38.638 1.00 27.29 ? 781 ASN A C 1 ATOM 6241 O O . ASN A 1 781 ? -6.231 17.738 38.483 1.00 28.03 ? 781 ASN A O 1 ATOM 6242 C CB . ASN A 1 781 ? -3.930 16.141 37.614 1.00 28.61 ? 781 ASN A CB 1 ATOM 6243 C CG . ASN A 1 781 ? -2.543 15.616 37.854 1.00 31.81 ? 781 ASN A CG 1 ATOM 6244 O OD1 . ASN A 1 781 ? -1.864 15.139 36.939 1.00 34.49 ? 781 ASN A OD1 1 ATOM 6245 N ND2 . ASN A 1 781 ? -2.129 15.649 39.109 1.00 30.83 ? 781 ASN A ND2 1 ATOM 6246 N N . LYS A 1 782 ? -7.297 15.778 38.716 1.00 26.33 ? 782 LYS A N 1 ATOM 6247 C CA . LYS A 1 782 ? -8.667 16.350 38.695 1.00 25.76 ? 782 LYS A CA 1 ATOM 6248 C C . LYS A 1 782 ? -9.016 17.246 37.506 1.00 24.64 ? 782 LYS A C 1 ATOM 6249 O O . LYS A 1 782 ? -9.539 18.361 37.682 1.00 24.62 ? 782 LYS A O 1 ATOM 6250 C CB . LYS A 1 782 ? -8.968 17.089 40.004 1.00 26.56 ? 782 LYS A CB 1 ATOM 6251 C CG . LYS A 1 782 ? -8.849 16.258 41.234 1.00 27.67 ? 782 LYS A CG 1 ATOM 6252 C CD . LYS A 1 782 ? -10.176 15.567 41.494 1.00 35.46 ? 782 LYS A CD 1 ATOM 6253 C CE . LYS A 1 782 ? -10.278 15.095 42.946 1.00 38.31 ? 782 LYS A CE 1 ATOM 6254 N NZ . LYS A 1 782 ? -11.184 13.904 43.035 1.00 40.94 ? 782 LYS A NZ 1 ATOM 6255 N N . VAL A 1 783 ? -8.753 16.739 36.307 1.00 22.08 ? 783 VAL A N 1 ATOM 6256 C CA . VAL A 1 783 ? -9.115 17.383 35.055 1.00 21.04 ? 783 VAL A CA 1 ATOM 6257 C C . VAL A 1 783 ? -10.142 16.452 34.416 1.00 19.54 ? 783 VAL A C 1 ATOM 6258 O O . VAL A 1 783 ? -9.845 15.631 33.548 1.00 18.94 ? 783 VAL A O 1 ATOM 6259 C CB . VAL A 1 783 ? -7.863 17.646 34.134 1.00 20.60 ? 783 VAL A CB 1 ATOM 6260 C CG1 . VAL A 1 783 ? -8.242 18.412 32.897 1.00 21.60 ? 783 VAL A CG1 1 ATOM 6261 C CG2 . VAL A 1 783 ? -6.779 18.433 34.909 1.00 23.21 ? 783 VAL A CG2 1 ATOM 6262 N N . TYR A 1 784 ? -11.388 16.566 34.871 1.00 17.73 ? 784 TYR A N 1 ATOM 6263 C CA . TYR A 1 784 ? -12.407 15.740 34.274 1.00 16.87 ? 784 TYR A CA 1 ATOM 6264 C C . TYR A 1 784 ? -13.771 16.273 34.634 1.00 15.62 ? 784 TYR A C 1 ATOM 6265 O O . TYR A 1 784 ? -13.888 17.108 35.522 1.00 16.60 ? 784 TYR A O 1 ATOM 6266 C CB . TYR A 1 784 ? -12.305 14.291 34.740 1.00 16.51 ? 784 TYR A CB 1 ATOM 6267 C CG . TYR A 1 784 ? -12.465 13.973 36.240 1.00 17.99 ? 784 TYR A CG 1 ATOM 6268 C CD1 . TYR A 1 784 ? -13.707 13.619 36.805 1.00 17.32 ? 784 TYR A CD1 1 ATOM 6269 C CD2 . TYR A 1 784 ? -11.352 13.921 37.065 1.00 17.99 ? 784 TYR A CD2 1 ATOM 6270 C CE1 . TYR A 1 784 ? -13.807 13.274 38.170 1.00 20.03 ? 784 TYR A CE1 1 ATOM 6271 C CE2 . TYR A 1 784 ? -11.442 13.580 38.402 1.00 18.48 ? 784 TYR A CE2 1 ATOM 6272 C CZ . TYR A 1 784 ? -12.674 13.257 38.947 1.00 21.16 ? 784 TYR A CZ 1 ATOM 6273 O OH . TYR A 1 784 ? -12.702 12.916 40.266 1.00 20.52 ? 784 TYR A OH 1 ATOM 6274 N N . LEU A 1 785 ? -14.764 15.753 33.940 1.00 16.12 ? 785 LEU A N 1 ATOM 6275 C CA . LEU A 1 785 ? -16.175 16.091 34.200 1.00 16.43 ? 785 LEU A CA 1 ATOM 6276 C C . LEU A 1 785 ? -16.768 14.835 34.808 1.00 16.57 ? 785 LEU A C 1 ATOM 6277 O O . LEU A 1 785 ? -16.478 13.725 34.338 1.00 16.11 ? 785 LEU A O 1 ATOM 6278 C CB . LEU A 1 785 ? -16.882 16.399 32.884 1.00 17.30 ? 785 LEU A CB 1 ATOM 6279 C CG . LEU A 1 785 ? -18.436 16.453 32.853 1.00 19.37 ? 785 LEU A CG 1 ATOM 6280 C CD1 . LEU A 1 785 ? -19.020 17.497 33.772 1.00 22.47 ? 785 LEU A CD1 1 ATOM 6281 C CD2 . LEU A 1 785 ? -18.874 16.686 31.455 1.00 24.34 ? 785 LEU A CD2 1 ATOM 6282 N N . LEU A 1 786 ? -17.572 14.984 35.862 1.00 16.18 ? 786 LEU A N 1 ATOM 6283 C CA . LEU A 1 786 ? -18.348 13.868 36.361 1.00 16.43 ? 786 LEU A CA 1 ATOM 6284 C C . LEU A 1 786 ? -19.740 14.436 36.600 1.00 17.16 ? 786 LEU A C 1 ATOM 6285 O O . LEU A 1 786 ? -19.892 15.406 37.338 1.00 18.38 ? 786 LEU A O 1 ATOM 6286 C CB . LEU A 1 786 ? -17.765 13.309 37.655 1.00 16.26 ? 786 LEU A CB 1 ATOM 6287 C CG . LEU A 1 786 ? -18.468 12.106 38.297 1.00 15.87 ? 786 LEU A CG 1 ATOM 6288 C CD1 . LEU A 1 786 ? -18.488 10.887 37.353 1.00 18.57 ? 786 LEU A CD1 1 ATOM 6289 C CD2 . LEU A 1 786 ? -17.892 11.806 39.663 1.00 17.32 ? 786 LEU A CD2 1 ATOM 6290 N N . CYS A 1 787 ? -20.743 13.869 35.959 1.00 18.24 ? 787 CYS A N 1 ATOM 6291 C CA . CYS A 1 787 ? -22.102 14.349 36.249 1.00 19.22 ? 787 CYS A CA 1 ATOM 6292 C C . CYS A 1 787 ? -22.985 13.207 36.689 1.00 18.89 ? 787 CYS A C 1 ATOM 6293 O O . CYS A 1 787 ? -22.663 12.060 36.471 1.00 16.19 ? 787 CYS A O 1 ATOM 6294 C CB . CYS A 1 787 ? -22.727 15.027 35.070 1.00 21.03 ? 787 CYS A CB 1 ATOM 6295 S SG . CYS A 1 787 ? -22.523 14.303 33.515 1.00 30.58 ? 787 CYS A SG 1 ATOM 6296 N N . GLU A 1 788 ? -24.119 13.551 37.290 1.00 17.97 ? 788 GLU A N 1 ATOM 6297 C CA . GLU A 1 788 ? -24.983 12.559 37.889 1.00 18.42 ? 788 GLU A CA 1 ATOM 6298 C C . GLU A 1 788 ? -26.323 12.825 37.291 1.00 17.70 ? 788 GLU A C 1 ATOM 6299 O O . GLU A 1 788 ? -26.689 13.996 37.087 1.00 19.47 ? 788 GLU A O 1 ATOM 6300 C CB . GLU A 1 788 ? -25.062 12.738 39.411 1.00 19.61 ? 788 GLU A CB 1 ATOM 6301 C CG . GLU A 1 788 ? -23.785 12.381 40.111 1.00 26.01 ? 788 GLU A CG 1 ATOM 6302 C CD . GLU A 1 788 ? -22.886 13.576 40.261 1.00 33.43 ? 788 GLU A CD 1 ATOM 6303 O OE1 . GLU A 1 788 ? -21.671 13.428 39.971 1.00 33.75 ? 788 GLU A OE1 1 ATOM 6304 O OE2 . GLU A 1 788 ? -23.394 14.672 40.670 1.00 35.32 ? 788 GLU A OE2 1 ATOM 6305 N N . PHE A 1 789 ? -27.035 11.753 36.993 1.00 16.94 ? 789 PHE A N 1 ATOM 6306 C CA . PHE A 1 789 ? -28.397 11.828 36.427 1.00 16.05 ? 789 PHE A CA 1 ATOM 6307 C C . PHE A 1 789 ? -29.325 11.198 37.430 1.00 17.09 ? 789 PHE A C 1 ATOM 6308 O O . PHE A 1 789 ? -29.008 10.154 38.005 1.00 16.80 ? 789 PHE A O 1 ATOM 6309 C CB . PHE A 1 789 ? -28.477 11.000 35.140 1.00 15.94 ? 789 PHE A CB 1 ATOM 6310 C CG . PHE A 1 789 ? -27.372 11.304 34.140 1.00 18.73 ? 789 PHE A CG 1 ATOM 6311 C CD1 . PHE A 1 789 ? -27.242 12.583 33.575 1.00 18.64 ? 789 PHE A CD1 1 ATOM 6312 C CD2 . PHE A 1 789 ? -26.469 10.298 33.765 1.00 18.98 ? 789 PHE A CD2 1 ATOM 6313 C CE1 . PHE A 1 789 ? -26.211 12.872 32.643 1.00 20.91 ? 789 PHE A CE1 1 ATOM 6314 C CE2 . PHE A 1 789 ? -25.434 10.572 32.824 1.00 20.23 ? 789 PHE A CE2 1 ATOM 6315 C CZ . PHE A 1 789 ? -25.310 11.852 32.276 1.00 20.16 ? 789 PHE A CZ 1 ATOM 6316 N N . SER A 1 790 ? -30.493 11.807 37.649 1.00 17.33 ? 790 SER A N 1 ATOM 6317 C CA . SER A 1 790 ? -31.481 11.147 38.493 1.00 19.23 ? 790 SER A CA 1 ATOM 6318 C C . SER A 1 790 ? -32.855 11.506 38.010 1.00 18.91 ? 790 SER A C 1 ATOM 6319 O O . SER A 1 790 ? -33.092 12.635 37.617 1.00 18.86 ? 790 SER A O 1 ATOM 6320 C CB . SER A 1 790 ? -31.338 11.475 39.983 1.00 20.16 ? 790 SER A CB 1 ATOM 6321 O OG . SER A 1 790 ? -31.325 12.867 40.223 1.00 25.53 ? 790 SER A OG 1 ATOM 6322 N N . VAL A 1 791 ? -33.748 10.538 38.102 1.00 20.97 ? 791 VAL A N 1 ATOM 6323 C CA . VAL A 1 791 ? -35.125 10.680 37.682 1.00 22.34 ? 791 VAL A CA 1 ATOM 6324 C C . VAL A 1 791 ? -35.974 10.237 38.881 1.00 24.44 ? 791 VAL A C 1 ATOM 6325 O O . VAL A 1 791 ? -35.798 9.149 39.398 1.00 22.05 ? 791 VAL A O 1 ATOM 6326 C CB . VAL A 1 791 ? -35.400 9.812 36.428 1.00 22.35 ? 791 VAL A CB 1 ATOM 6327 C CG1 . VAL A 1 791 ? -36.926 9.722 36.123 1.00 24.47 ? 791 VAL A CG1 1 ATOM 6328 C CG2 . VAL A 1 791 ? -34.614 10.337 35.230 1.00 22.53 ? 791 VAL A CG2 1 ATOM 6329 N N . THR A 1 792 ? -36.830 11.132 39.364 1.00 26.84 ? 792 THR A N 1 ATOM 6330 C CA . THR A 1 792 ? -37.743 10.824 40.472 1.00 30.61 ? 792 THR A CA 1 ATOM 6331 C C . THR A 1 792 ? -38.917 11.636 40.120 1.00 31.79 ? 792 THR A C 1 ATOM 6332 O O . THR A 1 792 ? -38.766 12.860 39.912 1.00 31.43 ? 792 THR A O 1 ATOM 6333 C CB . THR A 1 792 ? -37.329 11.370 41.830 1.00 30.07 ? 792 THR A CB 1 ATOM 6334 O OG1 . THR A 1 792 ? -35.908 11.457 41.944 1.00 37.00 ? 792 THR A OG1 1 ATOM 6335 C CG2 . THR A 1 792 ? -37.887 10.479 42.920 1.00 32.84 ? 792 THR A CG2 1 ATOM 6336 N N . GLN A 1 793 ? -40.064 10.953 40.154 1.00 33.37 ? 793 GLN A N 1 ATOM 6337 C CA . GLN A 1 793 ? -41.223 11.151 39.272 1.00 35.33 ? 793 GLN A CA 1 ATOM 6338 C C . GLN A 1 793 ? -41.388 12.514 38.593 1.00 33.51 ? 793 GLN A C 1 ATOM 6339 O O . GLN A 1 793 ? -41.276 13.575 39.222 1.00 34.48 ? 793 GLN A O 1 ATOM 6340 C CB . GLN A 1 793 ? -42.522 10.587 39.905 1.00 35.43 ? 793 GLN A CB 1 ATOM 6341 C CG . GLN A 1 793 ? -42.300 9.140 40.454 1.00 38.95 ? 793 GLN A CG 1 ATOM 6342 C CD . GLN A 1 793 ? -43.573 8.320 40.645 1.00 39.61 ? 793 GLN A CD 1 ATOM 6343 O OE1 . GLN A 1 793 ? -44.167 7.814 39.673 1.00 45.66 ? 793 GLN A OE1 1 ATOM 6344 N NE2 . GLN A 1 793 ? -43.966 8.131 41.903 1.00 42.58 ? 793 GLN A NE2 1 ATOM 6345 N N . ASN A 1 794 ? -41.591 12.452 37.277 1.00 31.66 ? 794 ASN A N 1 ATOM 6346 C CA . ASN A 1 794 ? -41.870 13.634 36.460 1.00 30.81 ? 794 ASN A CA 1 ATOM 6347 C C . ASN A 1 794 ? -40.610 14.469 36.186 1.00 27.94 ? 794 ASN A C 1 ATOM 6348 O O . ASN A 1 794 ? -40.742 15.550 35.644 1.00 26.69 ? 794 ASN A O 1 ATOM 6349 C CB . ASN A 1 794 ? -42.894 14.599 37.132 1.00 31.72 ? 794 ASN A CB 1 ATOM 6350 C CG . ASN A 1 794 ? -44.252 13.947 37.439 1.00 36.15 ? 794 ASN A CG 1 ATOM 6351 O OD1 . ASN A 1 794 ? -44.571 13.675 38.607 1.00 40.34 ? 794 ASN A OD1 1 ATOM 6352 N ND2 . ASN A 1 794 ? -45.068 13.735 36.400 1.00 36.10 ? 794 ASN A ND2 1 ATOM 6353 N N . ARG A 1 795 ? -39.418 14.031 36.618 1.00 25.66 ? 795 ARG A N 1 ATOM 6354 C CA . ARG A 1 795 ? -38.277 14.967 36.604 1.00 24.33 ? 795 ARG A CA 1 ATOM 6355 C C . ARG A 1 795 ? -36.917 14.282 36.421 1.00 23.05 ? 795 ARG A C 1 ATOM 6356 O O . ARG A 1 795 ? -36.585 13.438 37.223 1.00 22.78 ? 795 ARG A O 1 ATOM 6357 C CB . ARG A 1 795 ? -38.269 15.748 37.913 1.00 24.20 ? 795 ARG A CB 1 ATOM 6358 C CG . ARG A 1 795 ? -37.239 16.852 38.079 1.00 26.41 ? 795 ARG A CG 1 ATOM 6359 C CD . ARG A 1 795 ? -37.469 17.565 39.405 1.00 27.22 ? 795 ARG A CD 1 ATOM 6360 N NE . ARG A 1 795 ? -36.532 18.667 39.634 1.00 36.54 ? 795 ARG A NE 1 ATOM 6361 C CZ . ARG A 1 795 ? -36.879 19.901 40.010 1.00 39.39 ? 795 ARG A CZ 1 ATOM 6362 N NH1 . ARG A 1 795 ? -38.164 20.209 40.204 1.00 42.78 ? 795 ARG A NH1 1 ATOM 6363 N NH2 . ARG A 1 795 ? -35.940 20.837 40.202 1.00 40.39 ? 795 ARG A NH2 1 ATOM 6364 N N . LEU A 1 796 ? -36.146 14.699 35.416 1.00 20.47 ? 796 LEU A N 1 ATOM 6365 C CA . LEU A 1 796 ? -34.739 14.272 35.286 1.00 20.01 ? 796 LEU A CA 1 ATOM 6366 C C . LEU A 1 796 ? -33.901 15.443 35.735 1.00 19.65 ? 796 LEU A C 1 ATOM 6367 O O . LEU A 1 796 ? -34.141 16.582 35.312 1.00 19.78 ? 796 LEU A O 1 ATOM 6368 C CB . LEU A 1 796 ? -34.410 13.900 33.827 1.00 19.89 ? 796 LEU A CB 1 ATOM 6369 C CG . LEU A 1 796 ? -32.953 13.989 33.377 1.00 19.80 ? 796 LEU A CG 1 ATOM 6370 C CD1 . LEU A 1 796 ? -32.157 12.830 34.018 1.00 15.91 ? 796 LEU A CD1 1 ATOM 6371 C CD2 . LEU A 1 796 ? -32.836 13.955 31.850 1.00 19.30 ? 796 LEU A CD2 1 ATOM 6372 N N . GLU A 1 797 ? -32.935 15.199 36.609 1.00 20.54 ? 797 GLU A N 1 ATOM 6373 C CA . GLU A 1 797 ? -31.958 16.218 36.957 1.00 22.08 ? 797 GLU A CA 1 ATOM 6374 C C . GLU A 1 797 ? -30.612 15.784 36.413 1.00 21.36 ? 797 GLU A C 1 ATOM 6375 O O . GLU A 1 797 ? -30.262 14.598 36.509 1.00 20.17 ? 797 GLU A O 1 ATOM 6376 C CB . GLU A 1 797 ? -31.880 16.418 38.484 1.00 22.26 ? 797 GLU A CB 1 ATOM 6377 C CG . GLU A 1 797 ? -33.164 16.981 39.096 1.00 27.35 ? 797 GLU A CG 1 ATOM 6378 C CD . GLU A 1 797 ? -33.272 16.773 40.599 1.00 29.05 ? 797 GLU A CD 1 ATOM 6379 O OE1 . GLU A 1 797 ? -32.215 16.717 41.303 1.00 38.54 ? 797 GLU A OE1 1 ATOM 6380 O OE2 . GLU A 1 797 ? -34.432 16.680 41.083 1.00 39.18 ? 797 GLU A OE2 1 ATOM 6381 N N . VAL A 1 798 ? -29.890 16.731 35.804 1.00 21.60 ? 798 VAL A N 1 ATOM 6382 C CA . VAL A 1 798 ? -28.473 16.525 35.432 1.00 22.14 ? 798 VAL A CA 1 ATOM 6383 C C . VAL A 1 798 ? -27.680 17.441 36.354 1.00 22.27 ? 798 VAL A C 1 ATOM 6384 O O . VAL A 1 798 ? -27.873 18.650 36.345 1.00 21.68 ? 798 VAL A O 1 ATOM 6385 C CB . VAL A 1 798 ? -28.212 16.841 33.917 1.00 22.11 ? 798 VAL A CB 1 ATOM 6386 C CG1 . VAL A 1 798 ? -26.778 16.513 33.529 1.00 22.00 ? 798 VAL A CG1 1 ATOM 6387 C CG2 . VAL A 1 798 ? -29.158 16.078 33.043 1.00 22.88 ? 798 VAL A CG2 1 ATOM 6388 N N . ASN A 1 799 ? -26.828 16.849 37.185 1.00 23.16 ? 799 ASN A N 1 ATOM 6389 C CA . ASN A 1 799 ? -26.158 17.503 38.279 1.00 24.58 ? 799 ASN A CA 1 ATOM 6390 C C . ASN A 1 799 ? -24.651 17.329 38.070 1.00 24.95 ? 799 ASN A C 1 ATOM 6391 O O . ASN A 1 799 ? -24.187 16.229 37.748 1.00 25.09 ? 799 ASN A O 1 ATOM 6392 C CB . ASN A 1 799 ? -26.596 16.787 39.564 1.00 26.20 ? 799 ASN A CB 1 ATOM 6393 C CG . ASN A 1 799 ? -26.353 17.600 40.813 1.00 30.94 ? 799 ASN A CG 1 ATOM 6394 O OD1 . ASN A 1 799 ? -25.281 18.199 40.997 1.00 38.91 ? 799 ASN A OD1 1 ATOM 6395 N ND2 . ASN A 1 799 ? -27.335 17.603 41.710 1.00 35.25 ? 799 ASN A ND2 1 ATOM 6396 N N . ILE A 1 800 ? -23.887 18.398 38.222 1.00 24.10 ? 800 ILE A N 1 ATOM 6397 C CA . ILE A 1 800 ? -22.459 18.327 37.943 1.00 24.05 ? 800 ILE A CA 1 ATOM 6398 C C . ILE A 1 800 ? -21.683 18.250 39.250 1.00 23.82 ? 800 ILE A C 1 ATOM 6399 O O . ILE A 1 800 ? -21.780 19.140 40.086 1.00 23.27 ? 800 ILE A O 1 ATOM 6400 C CB . ILE A 1 800 ? -21.986 19.562 37.136 1.00 24.44 ? 800 ILE A CB 1 ATOM 6401 C CG1 . ILE A 1 800 ? -22.952 19.889 35.985 1.00 23.99 ? 800 ILE A CG1 1 ATOM 6402 C CG2 . ILE A 1 800 ? -20.585 19.367 36.632 1.00 23.51 ? 800 ILE A CG2 1 ATOM 6403 C CD1 . ILE A 1 800 ? -23.202 18.755 34.959 1.00 27.22 ? 800 ILE A CD1 1 ATOM 6404 N N . SER A 1 801 ? -20.907 17.190 39.436 1.00 23.46 ? 801 SER A N 1 ATOM 6405 C CA . SER A 1 801 ? -20.142 17.073 40.653 1.00 24.91 ? 801 SER A CA 1 ATOM 6406 C C . SER A 1 801 ? -18.668 17.502 40.483 1.00 25.02 ? 801 SER A C 1 ATOM 6407 O O . SER A 1 801 ? -18.095 18.024 41.409 1.00 26.80 ? 801 SER A O 1 ATOM 6408 C CB . SER A 1 801 ? -20.267 15.670 41.250 1.00 25.83 ? 801 SER A CB 1 ATOM 6409 O OG . SER A 1 801 ? -19.374 14.742 40.655 1.00 28.53 ? 801 SER A OG 1 ATOM 6410 N N . GLN A 1 802 ? -18.082 17.302 39.305 1.00 24.28 ? 802 GLN A N 1 ATOM 6411 C CA . GLN A 1 802 ? -16.696 17.763 39.021 1.00 23.73 ? 802 GLN A CA 1 ATOM 6412 C C . GLN A 1 802 ? -16.780 18.345 37.648 1.00 23.66 ? 802 GLN A C 1 ATOM 6413 O O . GLN A 1 802 ? -17.415 17.775 36.757 1.00 22.36 ? 802 GLN A O 1 ATOM 6414 C CB . GLN A 1 802 ? -15.692 16.605 39.060 1.00 24.11 ? 802 GLN A CB 1 ATOM 6415 C CG . GLN A 1 802 ? -14.193 16.978 38.751 1.00 24.81 ? 802 GLN A CG 1 ATOM 6416 C CD . GLN A 1 802 ? -13.518 17.734 39.872 1.00 28.87 ? 802 GLN A CD 1 ATOM 6417 O OE1 . GLN A 1 802 ? -12.647 18.593 39.641 1.00 31.52 ? 802 GLN A OE1 1 ATOM 6418 N NE2 . GLN A 1 802 ? -13.913 17.440 41.088 1.00 27.43 ? 802 GLN A NE2 1 ATOM 6419 N N . SER A 1 803 ? -16.175 19.509 37.468 1.00 23.65 ? 803 SER A N 1 ATOM 6420 C CA . SER A 1 803 ? -16.341 20.233 36.241 1.00 25.08 ? 803 SER A CA 1 ATOM 6421 C C . SER A 1 803 ? -15.027 20.920 35.902 1.00 25.36 ? 803 SER A C 1 ATOM 6422 O O . SER A 1 803 ? -14.943 22.144 35.835 1.00 26.22 ? 803 SER A O 1 ATOM 6423 C CB . SER A 1 803 ? -17.479 21.251 36.418 1.00 26.08 ? 803 SER A CB 1 ATOM 6424 O OG . SER A 1 803 ? -17.355 22.262 35.461 1.00 29.41 ? 803 SER A OG 1 ATOM 6425 N N . THR A 1 804 ? -13.978 20.126 35.730 1.00 24.16 ? 804 THR A N 1 ATOM 6426 C CA . THR A 1 804 ? -12.678 20.710 35.432 1.00 23.92 ? 804 THR A CA 1 ATOM 6427 C C . THR A 1 804 ? -12.138 20.319 34.062 1.00 23.43 ? 804 THR A C 1 ATOM 6428 O O . THR A 1 804 ? -10.978 20.590 33.745 1.00 24.45 ? 804 THR A O 1 ATOM 6429 C CB . THR A 1 804 ? -11.661 20.403 36.530 1.00 23.10 ? 804 THR A CB 1 ATOM 6430 O OG1 . THR A 1 804 ? -11.722 19.012 36.856 1.00 21.90 ? 804 THR A OG1 1 ATOM 6431 C CG2 . THR A 1 804 ? -11.951 21.234 37.774 1.00 23.32 ? 804 THR A CG2 1 ATOM 6432 N N . TYR A 1 805 ? -12.988 19.712 33.239 1.00 22.56 ? 805 TYR A N 1 ATOM 6433 C CA . TYR A 1 805 ? -12.656 19.466 31.867 1.00 22.58 ? 805 TYR A CA 1 ATOM 6434 C C . TYR A 1 805 ? -13.820 19.839 30.967 1.00 22.78 ? 805 TYR A C 1 ATOM 6435 O O . TYR A 1 805 ? -14.939 19.343 31.151 1.00 22.96 ? 805 TYR A O 1 ATOM 6436 C CB . TYR A 1 805 ? -12.295 17.987 31.611 1.00 21.38 ? 805 TYR A CB 1 ATOM 6437 C CG . TYR A 1 805 ? -11.955 17.748 30.163 1.00 20.94 ? 805 TYR A CG 1 ATOM 6438 C CD1 . TYR A 1 805 ? -10.761 18.275 29.604 1.00 19.50 ? 805 TYR A CD1 1 ATOM 6439 C CD2 . TYR A 1 805 ? -12.817 17.041 29.336 1.00 19.30 ? 805 TYR A CD2 1 ATOM 6440 C CE1 . TYR A 1 805 ? -10.463 18.074 28.279 1.00 20.01 ? 805 TYR A CE1 1 ATOM 6441 C CE2 . TYR A 1 805 ? -12.539 16.857 28.002 1.00 20.65 ? 805 TYR A CE2 1 ATOM 6442 C CZ . TYR A 1 805 ? -11.354 17.347 27.488 1.00 21.11 ? 805 TYR A CZ 1 ATOM 6443 O OH . TYR A 1 805 ? -11.102 17.147 26.177 1.00 19.36 ? 805 TYR A OH 1 ATOM 6444 N N . LYS A 1 806 ? -13.566 20.664 29.967 1.00 22.14 ? 806 LYS A N 1 ATOM 6445 C CA . LYS A 1 806 ? -14.640 20.924 29.020 1.00 23.10 ? 806 LYS A CA 1 ATOM 6446 C C . LYS A 1 806 ? -14.200 20.538 27.634 1.00 22.00 ? 806 LYS A C 1 ATOM 6447 O O . LYS A 1 806 ? -13.279 21.126 27.057 1.00 21.58 ? 806 LYS A O 1 ATOM 6448 C CB . LYS A 1 806 ? -15.169 22.367 29.091 1.00 24.21 ? 806 LYS A CB 1 ATOM 6449 C CG . LYS A 1 806 ? -16.359 22.582 28.139 1.00 26.31 ? 806 LYS A CG 1 ATOM 6450 C CD . LYS A 1 806 ? -17.383 23.541 28.707 1.00 30.98 ? 806 LYS A CD 1 ATOM 6451 C CE . LYS A 1 806 ? -18.596 23.628 27.783 1.00 31.57 ? 806 LYS A CE 1 ATOM 6452 N NZ . LYS A 1 806 ? -19.496 24.728 28.203 1.00 36.14 ? 806 LYS A NZ 1 ATOM 6453 N N . ASP A 1 807 ? -14.876 19.530 27.100 1.00 20.10 ? 807 ASP A N 1 ATOM 6454 C CA . ASP A 1 807 ? -14.582 19.003 25.778 1.00 19.49 ? 807 ASP A CA 1 ATOM 6455 C C . ASP A 1 807 ? -14.777 20.053 24.687 1.00 19.77 ? 807 ASP A C 1 ATOM 6456 O O . ASP A 1 807 ? -15.834 20.684 24.608 1.00 17.00 ? 807 ASP A O 1 ATOM 6457 C CB . ASP A 1 807 ? -15.501 17.803 25.512 1.00 20.53 ? 807 ASP A CB 1 ATOM 6458 C CG . ASP A 1 807 ? -15.064 16.993 24.308 1.00 22.99 ? 807 ASP A CG 1 ATOM 6459 O OD1 . ASP A 1 807 ? -15.126 17.533 23.193 1.00 25.87 ? 807 ASP A OD1 1 ATOM 6460 O OD2 . ASP A 1 807 ? -14.667 15.825 24.480 1.00 23.40 ? 807 ASP A OD2 1 ATOM 6461 N N . PRO A 1 808 ? -13.746 20.266 23.836 1.00 20.16 ? 808 PRO A N 1 ATOM 6462 C CA . PRO A 1 808 ? -13.879 21.337 22.837 1.00 20.30 ? 808 PRO A CA 1 ATOM 6463 C C . PRO A 1 808 ? -14.858 21.085 21.664 1.00 20.97 ? 808 PRO A C 1 ATOM 6464 O O . PRO A 1 808 ? -15.079 21.975 20.832 1.00 21.11 ? 808 PRO A O 1 ATOM 6465 C CB . PRO A 1 808 ? -12.431 21.517 22.339 1.00 20.94 ? 808 PRO A CB 1 ATOM 6466 C CG . PRO A 1 808 ? -11.807 20.125 22.474 1.00 20.44 ? 808 PRO A CG 1 ATOM 6467 C CD . PRO A 1 808 ? -12.425 19.593 23.783 1.00 20.65 ? 808 PRO A CD 1 ATOM 6468 N N . ASN A 1 809 ? -15.427 19.885 21.584 1.00 19.60 ? 809 ASN A N 1 ATOM 6469 C CA . ASN A 1 809 ? -16.247 19.513 20.453 1.00 20.24 ? 809 ASN A CA 1 ATOM 6470 C C . ASN A 1 809 ? -17.726 19.824 20.626 1.00 20.63 ? 809 ASN A C 1 ATOM 6471 O O . ASN A 1 809 ? -18.545 19.230 19.929 1.00 21.57 ? 809 ASN A O 1 ATOM 6472 C CB . ASN A 1 809 ? -16.089 18.024 20.143 1.00 20.31 ? 809 ASN A CB 1 ATOM 6473 C CG . ASN A 1 809 ? -14.725 17.710 19.590 1.00 21.57 ? 809 ASN A CG 1 ATOM 6474 O OD1 . ASN A 1 809 ? -14.017 16.855 20.096 1.00 24.37 ? 809 ASN A OD1 1 ATOM 6475 N ND2 . ASN A 1 809 ? -14.343 18.436 18.582 1.00 17.35 ? 809 ASN A ND2 1 ATOM 6476 N N . ASN A 1 810 ? -18.063 20.726 21.529 1.00 20.79 ? 810 ASN A N 1 ATOM 6477 C CA . ASN A 1 810 ? -19.497 21.183 21.654 1.00 21.19 ? 810 ASN A CA 1 ATOM 6478 C C . ASN A 1 810 ? -20.468 20.001 21.874 1.00 20.52 ? 810 ASN A C 1 ATOM 6479 O O . ASN A 1 810 ? -21.511 19.870 21.174 1.00 20.36 ? 810 ASN A O 1 ATOM 6480 C CB . ASN A 1 810 ? -19.896 21.989 20.396 1.00 22.44 ? 810 ASN A CB 1 ATOM 6481 C CG . ASN A 1 810 ? -21.304 22.673 20.495 1.00 22.54 ? 810 ASN A CG 1 ATOM 6482 O OD1 . ASN A 1 810 ? -21.688 23.208 21.538 1.00 30.28 ? 810 ASN A OD1 1 ATOM 6483 N ND2 . ASN A 1 810 ? -22.013 22.714 19.364 1.00 27.65 ? 810 ASN A ND2 1 ATOM 6484 N N . LEU A 1 811 ? -20.129 19.134 22.824 1.00 18.20 ? 811 LEU A N 1 ATOM 6485 C CA . LEU A 1 811 ? -20.887 17.890 22.997 1.00 16.88 ? 811 LEU A CA 1 ATOM 6486 C C . LEU A 1 811 ? -22.134 18.196 23.775 1.00 15.86 ? 811 LEU A C 1 ATOM 6487 O O . LEU A 1 811 ? -22.125 18.988 24.721 1.00 15.00 ? 811 LEU A O 1 ATOM 6488 C CB . LEU A 1 811 ? -20.077 16.819 23.743 1.00 16.55 ? 811 LEU A CB 1 ATOM 6489 C CG . LEU A 1 811 ? -18.767 16.384 23.061 1.00 17.04 ? 811 LEU A CG 1 ATOM 6490 C CD1 . LEU A 1 811 ? -18.041 15.310 23.931 1.00 18.47 ? 811 LEU A CD1 1 ATOM 6491 C CD2 . LEU A 1 811 ? -19.022 15.867 21.622 1.00 14.67 ? 811 LEU A CD2 1 ATOM 6492 N N . ALA A 1 812 ? -23.211 17.528 23.390 1.00 16.70 ? 812 ALA A N 1 ATOM 6493 C CA . ALA A 1 812 ? -24.452 17.716 24.134 1.00 16.10 ? 812 ALA A CA 1 ATOM 6494 C C . ALA A 1 812 ? -25.293 16.461 23.997 1.00 16.26 ? 812 ALA A C 1 ATOM 6495 O O . ALA A 1 812 ? -25.174 15.727 23.022 1.00 16.37 ? 812 ALA A O 1 ATOM 6496 C CB . ALA A 1 812 ? -25.228 18.911 23.575 1.00 16.63 ? 812 ALA A CB 1 ATOM 6497 N N . PHE A 1 813 ? -26.158 16.257 24.981 1.00 16.74 ? 813 PHE A N 1 ATOM 6498 C CA . PHE A 1 813 ? -27.178 15.216 24.926 1.00 17.30 ? 813 PHE A CA 1 ATOM 6499 C C . PHE A 1 813 ? -28.268 15.717 24.010 1.00 18.69 ? 813 PHE A C 1 ATOM 6500 O O . PHE A 1 813 ? -28.886 16.750 24.305 1.00 19.67 ? 813 PHE A O 1 ATOM 6501 C CB . PHE A 1 813 ? -27.740 14.969 26.331 1.00 18.22 ? 813 PHE A CB 1 ATOM 6502 C CG . PHE A 1 813 ? -26.726 14.454 27.309 1.00 19.26 ? 813 PHE A CG 1 ATOM 6503 C CD1 . PHE A 1 813 ? -26.311 13.115 27.260 1.00 19.54 ? 813 PHE A CD1 1 ATOM 6504 C CD2 . PHE A 1 813 ? -26.160 15.292 28.260 1.00 20.44 ? 813 PHE A CD2 1 ATOM 6505 C CE1 . PHE A 1 813 ? -25.354 12.646 28.153 1.00 17.17 ? 813 PHE A CE1 1 ATOM 6506 C CE2 . PHE A 1 813 ? -25.183 14.807 29.166 1.00 22.23 ? 813 PHE A CE2 1 ATOM 6507 C CZ . PHE A 1 813 ? -24.787 13.481 29.099 1.00 18.41 ? 813 PHE A CZ 1 ATOM 6508 N N . ASN A 1 814 ? -28.505 15.027 22.898 1.00 18.13 ? 814 ASN A N 1 ATOM 6509 C CA . ASN A 1 814 ? -29.504 15.502 21.965 1.00 20.24 ? 814 ASN A CA 1 ATOM 6510 C C . ASN A 1 814 ? -30.681 14.545 21.866 1.00 19.89 ? 814 ASN A C 1 ATOM 6511 O O . ASN A 1 814 ? -31.528 14.707 21.009 1.00 20.24 ? 814 ASN A O 1 ATOM 6512 C CB . ASN A 1 814 ? -28.897 15.764 20.602 1.00 21.20 ? 814 ASN A CB 1 ATOM 6513 C CG . ASN A 1 814 ? -28.739 14.540 19.788 1.00 23.52 ? 814 ASN A CG 1 ATOM 6514 O OD1 . ASN A 1 814 ? -28.674 13.415 20.306 1.00 27.43 ? 814 ASN A OD1 1 ATOM 6515 N ND2 . ASN A 1 814 ? -28.644 14.734 18.468 1.00 30.30 ? 814 ASN A ND2 1 ATOM 6516 N N . GLU A 1 815 ? -30.665 13.509 22.698 1.00 20.18 ? 815 GLU A N 1 ATOM 6517 C CA . GLU A 1 815 ? -31.772 12.509 22.715 1.00 21.69 ? 815 GLU A CA 1 ATOM 6518 C C . GLU A 1 815 ? -31.856 11.910 24.106 1.00 20.76 ? 815 GLU A C 1 ATOM 6519 O O . GLU A 1 815 ? -30.826 11.562 24.722 1.00 18.87 ? 815 GLU A O 1 ATOM 6520 C CB . GLU A 1 815 ? -31.585 11.411 21.657 1.00 20.84 ? 815 GLU A CB 1 ATOM 6521 C CG . GLU A 1 815 ? -32.754 10.369 21.585 1.00 23.17 ? 815 GLU A CG 1 ATOM 6522 C CD . GLU A 1 815 ? -32.688 9.396 20.398 1.00 27.46 ? 815 GLU A CD 1 ATOM 6523 O OE1 . GLU A 1 815 ? -32.443 9.813 19.240 1.00 33.49 ? 815 GLU A OE1 1 ATOM 6524 O OE2 . GLU A 1 815 ? -32.937 8.183 20.621 1.00 38.33 ? 815 GLU A OE2 1 ATOM 6525 N N . ILE A 1 816 ? -33.091 11.789 24.608 1.00 19.40 ? 816 ILE A N 1 ATOM 6526 C CA . ILE A 1 816 ? -33.323 11.095 25.877 1.00 18.14 ? 816 ILE A CA 1 ATOM 6527 C C . ILE A 1 816 ? -34.386 10.008 25.586 1.00 17.52 ? 816 ILE A C 1 ATOM 6528 O O . ILE A 1 816 ? -35.449 10.313 25.067 1.00 16.98 ? 816 ILE A O 1 ATOM 6529 C CB . ILE A 1 816 ? -33.765 12.044 26.988 1.00 18.04 ? 816 ILE A CB 1 ATOM 6530 C CG1 . ILE A 1 816 ? -32.655 13.082 27.327 1.00 18.20 ? 816 ILE A CG1 1 ATOM 6531 C CG2 . ILE A 1 816 ? -34.135 11.278 28.261 1.00 18.55 ? 816 ILE A CG2 1 ATOM 6532 C CD1 . ILE A 1 816 ? -33.129 14.210 28.234 1.00 18.80 ? 816 ILE A CD1 1 ATOM 6533 N N . LYS A 1 817 ? -34.057 8.749 25.851 1.00 16.47 ? 817 LYS A N 1 ATOM 6534 C CA . LYS A 1 817 ? -35.009 7.655 25.650 1.00 17.67 ? 817 LYS A CA 1 ATOM 6535 C C . LYS A 1 817 ? -35.440 7.187 27.049 1.00 18.32 ? 817 LYS A C 1 ATOM 6536 O O . LYS A 1 817 ? -34.603 6.864 27.888 1.00 17.05 ? 817 LYS A O 1 ATOM 6537 C CB . LYS A 1 817 ? -34.424 6.530 24.780 1.00 18.04 ? 817 LYS A CB 1 ATOM 6538 C CG . LYS A 1 817 ? -35.297 5.296 24.594 1.00 20.59 ? 817 LYS A CG 1 ATOM 6539 C CD . LYS A 1 817 ? -34.679 4.378 23.567 1.00 23.99 ? 817 LYS A CD 1 ATOM 6540 C CE . LYS A 1 817 ? -35.681 3.507 22.865 1.00 29.12 ? 817 LYS A CE 1 ATOM 6541 N NZ . LYS A 1 817 ? -35.044 2.841 21.626 1.00 30.70 ? 817 LYS A NZ 1 ATOM 6542 N N . ILE A 1 818 ? -36.760 7.176 27.303 1.00 17.08 ? 818 ILE A N 1 ATOM 6543 C CA . ILE A 1 818 ? -37.280 6.783 28.618 1.00 17.85 ? 818 ILE A CA 1 ATOM 6544 C C . ILE A 1 818 ? -38.046 5.477 28.437 1.00 17.94 ? 818 ILE A C 1 ATOM 6545 O O . ILE A 1 818 ? -38.927 5.402 27.571 1.00 16.94 ? 818 ILE A O 1 ATOM 6546 C CB . ILE A 1 818 ? -38.232 7.860 29.232 1.00 17.26 ? 818 ILE A CB 1 ATOM 6547 C CG1 . ILE A 1 818 ? -37.550 9.246 29.281 1.00 18.97 ? 818 ILE A CG1 1 ATOM 6548 C CG2 . ILE A 1 818 ? -38.676 7.410 30.615 1.00 18.00 ? 818 ILE A CG2 1 ATOM 6549 C CD1 . ILE A 1 818 ? -38.569 10.440 29.566 1.00 20.86 ? 818 ILE A CD1 1 ATOM 6550 N N . LEU A 1 819 ? -37.650 4.443 29.184 1.00 16.75 ? 819 LEU A N 1 ATOM 6551 C CA . LEU A 1 819 ? -38.236 3.108 29.070 1.00 17.58 ? 819 LEU A CA 1 ATOM 6552 C C . LEU A 1 819 ? -39.150 2.909 30.276 1.00 17.20 ? 819 LEU A C 1 ATOM 6553 O O . LEU A 1 819 ? -38.818 3.301 31.376 1.00 17.29 ? 819 LEU A O 1 ATOM 6554 C CB . LEU A 1 819 ? -37.144 1.998 29.051 1.00 16.58 ? 819 LEU A CB 1 ATOM 6555 C CG . LEU A 1 819 ? -35.965 2.177 28.063 1.00 17.82 ? 819 LEU A CG 1 ATOM 6556 C CD1 . LEU A 1 819 ? -34.918 1.037 28.142 1.00 16.87 ? 819 LEU A CD1 1 ATOM 6557 C CD2 . LEU A 1 819 ? -36.531 2.286 26.630 1.00 11.82 ? 819 LEU A CD2 1 ATOM 6558 N N . GLY A 1 820 ? -40.284 2.273 30.062 1.00 17.75 ? 820 GLY A N 1 ATOM 6559 C CA . GLY A 1 820 ? -41.190 1.914 31.154 1.00 18.41 ? 820 GLY A CA 1 ATOM 6560 C C . GLY A 1 820 ? -42.057 3.075 31.606 1.00 19.77 ? 820 GLY A C 1 ATOM 6561 O O . GLY A 1 820 ? -42.475 3.153 32.772 1.00 19.77 ? 820 GLY A O 1 ATOM 6562 N N . THR A 1 821 ? -42.349 3.979 30.682 1.00 19.17 ? 821 THR A N 1 ATOM 6563 C CA . THR A 1 821 ? -43.076 5.193 31.031 1.00 20.31 ? 821 THR A CA 1 ATOM 6564 C C . THR A 1 821 ? -44.478 5.297 30.379 1.00 20.02 ? 821 THR A C 1 ATOM 6565 O O . THR A 1 821 ? -44.727 4.790 29.277 1.00 18.15 ? 821 THR A O 1 ATOM 6566 C CB . THR A 1 821 ? -42.238 6.441 30.721 1.00 20.31 ? 821 THR A CB 1 ATOM 6567 O OG1 . THR A 1 821 ? -42.931 7.612 31.152 1.00 23.11 ? 821 THR A OG1 1 ATOM 6568 C CG2 . THR A 1 821 ? -41.933 6.560 29.211 1.00 18.60 ? 821 THR A CG2 1 ATOM 6569 N N . GLU A 1 822 ? -45.402 5.943 31.092 1.00 21.58 ? 822 GLU A N 1 ATOM 6570 C CA . GLU A 1 822 ? -46.650 6.383 30.491 1.00 23.18 ? 822 GLU A CA 1 ATOM 6571 C C . GLU A 1 822 ? -46.333 7.616 29.647 1.00 23.82 ? 822 GLU A C 1 ATOM 6572 O O . GLU A 1 822 ? -45.306 8.258 29.855 1.00 24.11 ? 822 GLU A O 1 ATOM 6573 C CB . GLU A 1 822 ? -47.698 6.723 31.582 1.00 23.98 ? 822 GLU A CB 1 ATOM 6574 C CG . GLU A 1 822 ? -48.202 5.473 32.338 1.00 24.36 ? 822 GLU A CG 1 ATOM 6575 C CD . GLU A 1 822 ? -48.759 4.402 31.418 1.00 30.04 ? 822 GLU A CD 1 ATOM 6576 O OE1 . GLU A 1 822 ? -49.617 4.714 30.549 1.00 33.77 ? 822 GLU A OE1 1 ATOM 6577 O OE2 . GLU A 1 822 ? -48.349 3.234 31.562 1.00 32.87 ? 822 GLU A OE2 1 ATOM 6578 N N . GLU A 1 823 ? -47.218 7.984 28.730 1.00 24.98 ? 823 GLU A N 1 ATOM 6579 C CA . GLU A 1 823 ? -46.931 9.127 27.849 1.00 26.55 ? 823 GLU A CA 1 ATOM 6580 C C . GLU A 1 823 ? -46.525 10.416 28.593 1.00 26.98 ? 823 GLU A C 1 ATOM 6581 O O . GLU A 1 823 ? -47.305 10.918 29.419 1.00 27.29 ? 823 GLU A O 1 ATOM 6582 C CB . GLU A 1 823 ? -48.131 9.396 26.946 1.00 27.06 ? 823 GLU A CB 1 ATOM 6583 C CG . GLU A 1 823 ? -47.797 10.360 25.828 1.00 29.75 ? 823 GLU A CG 1 ATOM 6584 C CD . GLU A 1 823 ? -48.799 10.356 24.704 1.00 34.67 ? 823 GLU A CD 1 ATOM 6585 O OE1 . GLU A 1 823 ? -49.865 9.709 24.832 1.00 35.42 ? 823 GLU A OE1 1 ATOM 6586 O OE2 . GLU A 1 823 ? -48.500 11.011 23.685 1.00 36.25 ? 823 GLU A OE2 1 ATOM 6587 N N . PRO A 1 824 ? -45.304 10.943 28.345 1.00 27.56 ? 824 PRO A N 1 ATOM 6588 C CA . PRO A 1 824 ? -44.984 12.264 28.871 1.00 28.57 ? 824 PRO A CA 1 ATOM 6589 C C . PRO A 1 824 ? -45.736 13.374 28.115 1.00 30.10 ? 824 PRO A C 1 ATOM 6590 O O . PRO A 1 824 ? -45.888 13.301 26.881 1.00 31.92 ? 824 PRO A O 1 ATOM 6591 C CB . PRO A 1 824 ? -43.462 12.403 28.639 1.00 28.59 ? 824 PRO A CB 1 ATOM 6592 C CG . PRO A 1 824 ? -42.990 11.082 28.189 1.00 27.76 ? 824 PRO A CG 1 ATOM 6593 C CD . PRO A 1 824 ? -44.157 10.352 27.623 1.00 27.59 ? 824 PRO A CD 1 ATOM 6594 N N . SER A 1 825 ? -46.211 14.374 28.851 1.00 29.61 ? 825 SER A N 1 ATOM 6595 C CA . SER A 1 825 ? -46.732 15.594 28.240 1.00 30.78 ? 825 SER A CA 1 ATOM 6596 C C . SER A 1 825 ? -46.083 16.818 28.866 1.00 30.57 ? 825 SER A C 1 ATOM 6597 O O . SER A 1 825 ? -45.491 16.720 29.945 1.00 30.36 ? 825 SER A O 1 ATOM 6598 C CB . SER A 1 825 ? -48.250 15.662 28.403 1.00 30.22 ? 825 SER A CB 1 ATOM 6599 O OG . SER A 1 825 ? -48.600 15.754 29.772 1.00 31.99 ? 825 SER A OG 1 ATOM 6600 N N . ASN A 1 826 ? -46.193 17.961 28.182 1.00 30.83 ? 826 ASN A N 1 ATOM 6601 C CA . ASN A 1 826 ? -45.648 19.245 28.656 1.00 31.59 ? 826 ASN A CA 1 ATOM 6602 C C . ASN A 1 826 ? -44.183 19.152 29.066 1.00 30.57 ? 826 ASN A C 1 ATOM 6603 O O . ASN A 1 826 ? -43.829 19.597 30.159 1.00 30.01 ? 826 ASN A O 1 ATOM 6604 C CB . ASN A 1 826 ? -46.434 19.775 29.863 1.00 31.77 ? 826 ASN A CB 1 ATOM 6605 C CG . ASN A 1 826 ? -47.924 19.874 29.612 1.00 35.99 ? 826 ASN A CG 1 ATOM 6606 O OD1 . ASN A 1 826 ? -48.382 19.839 28.463 1.00 39.43 ? 826 ASN A OD1 1 ATOM 6607 N ND2 . ASN A 1 826 ? -48.694 20.000 30.698 1.00 38.42 ? 826 ASN A ND2 1 ATOM 6608 N N . VAL A 1 827 ? -43.348 18.574 28.206 1.00 30.01 ? 827 VAL A N 1 ATOM 6609 C CA . VAL A 1 827 ? -41.929 18.423 28.516 1.00 29.17 ? 827 VAL A CA 1 ATOM 6610 C C . VAL A 1 827 ? -41.238 19.784 28.510 1.00 28.96 ? 827 VAL A C 1 ATOM 6611 O O . VAL A 1 827 ? -41.337 20.540 27.551 1.00 29.33 ? 827 VAL A O 1 ATOM 6612 C CB . VAL A 1 827 ? -41.232 17.412 27.578 1.00 29.44 ? 827 VAL A CB 1 ATOM 6613 C CG1 . VAL A 1 827 ? -39.742 17.319 27.898 1.00 29.28 ? 827 VAL A CG1 1 ATOM 6614 C CG2 . VAL A 1 827 ? -41.894 16.059 27.683 1.00 28.38 ? 827 VAL A CG2 1 ATOM 6615 N N . THR A 1 828 ? -40.560 20.083 29.610 1.00 28.67 ? 828 THR A N 1 ATOM 6616 C CA . THR A 1 828 ? -39.978 21.381 29.880 1.00 28.95 ? 828 THR A CA 1 ATOM 6617 C C . THR A 1 828 ? -38.522 21.192 30.283 1.00 27.79 ? 828 THR A C 1 ATOM 6618 O O . THR A 1 828 ? -38.199 20.271 31.017 1.00 27.08 ? 828 THR A O 1 ATOM 6619 C CB . THR A 1 828 ? -40.766 22.089 31.007 1.00 29.30 ? 828 THR A CB 1 ATOM 6620 O OG1 . THR A 1 828 ? -42.042 22.511 30.487 1.00 32.24 ? 828 THR A OG1 1 ATOM 6621 C CG2 . THR A 1 828 ? -40.053 23.323 31.515 1.00 32.33 ? 828 THR A CG2 1 ATOM 6622 N N . VAL A 1 829 ? -37.665 22.089 29.821 1.00 26.97 ? 829 VAL A N 1 ATOM 6623 C CA . VAL A 1 829 ? -36.232 21.990 30.094 1.00 26.68 ? 829 VAL A CA 1 ATOM 6624 C C . VAL A 1 829 ? -35.815 23.288 30.761 1.00 26.94 ? 829 VAL A C 1 ATOM 6625 O O . VAL A 1 829 ? -36.124 24.376 30.251 1.00 27.79 ? 829 VAL A O 1 ATOM 6626 C CB . VAL A 1 829 ? -35.434 21.792 28.795 1.00 27.04 ? 829 VAL A CB 1 ATOM 6627 C CG1 . VAL A 1 829 ? -33.937 21.774 29.081 1.00 26.58 ? 829 VAL A CG1 1 ATOM 6628 C CG2 . VAL A 1 829 ? -35.899 20.567 28.058 1.00 25.08 ? 829 VAL A CG2 1 ATOM 6629 N N . LYS A 1 830 ? -35.181 23.185 31.924 1.00 25.92 ? 830 LYS A N 1 ATOM 6630 C CA . LYS A 1 830 ? -34.636 24.334 32.610 1.00 27.22 ? 830 LYS A CA 1 ATOM 6631 C C . LYS A 1 830 ? -33.123 24.191 32.637 1.00 27.76 ? 830 LYS A C 1 ATOM 6632 O O . LYS A 1 830 ? -32.617 23.084 32.721 1.00 25.88 ? 830 LYS A O 1 ATOM 6633 C CB . LYS A 1 830 ? -35.125 24.419 34.048 1.00 27.59 ? 830 LYS A CB 1 ATOM 6634 C CG . LYS A 1 830 ? -36.636 24.645 34.192 1.00 30.02 ? 830 LYS A CG 1 ATOM 6635 C CD . LYS A 1 830 ? -36.972 24.860 35.654 1.00 36.12 ? 830 LYS A CD 1 ATOM 6636 C CE . LYS A 1 830 ? -38.473 25.030 35.866 1.00 40.76 ? 830 LYS A CE 1 ATOM 6637 N NZ . LYS A 1 830 ? -38.822 24.998 37.329 1.00 42.29 ? 830 LYS A NZ 1 ATOM 6638 N N . HIS A 1 831 ? -32.430 25.321 32.618 1.00 29.24 ? 831 HIS A N 1 ATOM 6639 C CA . HIS A 1 831 ? -30.972 25.345 32.657 1.00 31.70 ? 831 HIS A CA 1 ATOM 6640 C C . HIS A 1 831 ? -30.567 26.215 33.844 1.00 33.37 ? 831 HIS A C 1 ATOM 6641 O O . HIS A 1 831 ? -30.862 27.411 33.875 1.00 33.60 ? 831 HIS A O 1 ATOM 6642 C CB . HIS A 1 831 ? -30.434 25.838 31.310 1.00 31.93 ? 831 HIS A CB 1 ATOM 6643 C CG . HIS A 1 831 ? -28.943 25.993 31.246 1.00 32.44 ? 831 HIS A CG 1 ATOM 6644 N ND1 . HIS A 1 831 ? -28.332 26.871 30.376 1.00 35.16 ? 831 HIS A ND1 1 ATOM 6645 C CD2 . HIS A 1 831 ? -27.942 25.402 31.945 1.00 34.26 ? 831 HIS A CD2 1 ATOM 6646 C CE1 . HIS A 1 831 ? -27.021 26.807 30.533 1.00 35.19 ? 831 HIS A CE1 1 ATOM 6647 N NE2 . HIS A 1 831 ? -26.758 25.924 31.480 1.00 34.83 ? 831 HIS A NE2 1 ATOM 6648 N N . ASN A 1 832 ? -29.926 25.589 34.833 1.00 35.69 ? 832 ASN A N 1 ATOM 6649 C CA . ASN A 1 832 ? -29.584 26.228 36.111 1.00 38.18 ? 832 ASN A CA 1 ATOM 6650 C C . ASN A 1 832 ? -30.840 26.751 36.830 1.00 39.22 ? 832 ASN A C 1 ATOM 6651 O O . ASN A 1 832 ? -30.775 27.734 37.570 1.00 39.27 ? 832 ASN A O 1 ATOM 6652 C CB . ASN A 1 832 ? -28.556 27.370 35.925 1.00 38.48 ? 832 ASN A CB 1 ATOM 6653 C CG . ASN A 1 832 ? -27.187 26.888 35.426 1.00 40.84 ? 832 ASN A CG 1 ATOM 6654 O OD1 . ASN A 1 832 ? -26.679 25.848 35.842 1.00 41.76 ? 832 ASN A OD1 1 ATOM 6655 N ND2 . ASN A 1 832 ? -26.578 27.672 34.531 1.00 42.14 ? 832 ASN A ND2 1 ATOM 6656 N N . GLY A 1 833 ? -31.978 26.099 36.592 1.00 40.10 ? 833 GLY A N 1 ATOM 6657 C CA . GLY A 1 833 ? -33.250 26.498 37.213 1.00 41.60 ? 833 GLY A CA 1 ATOM 6658 C C . GLY A 1 833 ? -34.098 27.453 36.392 1.00 42.68 ? 833 GLY A C 1 ATOM 6659 O O . GLY A 1 833 ? -35.232 27.780 36.779 1.00 42.94 ? 833 GLY A O 1 ATOM 6660 N N . VAL A 1 834 ? -33.565 27.873 35.244 1.00 43.33 ? 834 VAL A N 1 ATOM 6661 C CA . VAL A 1 834 ? -34.184 28.899 34.407 1.00 44.26 ? 834 VAL A CA 1 ATOM 6662 C C . VAL A 1 834 ? -34.798 28.297 33.147 1.00 45.04 ? 834 VAL A C 1 ATOM 6663 O O . VAL A 1 834 ? -34.096 27.659 32.347 1.00 44.47 ? 834 VAL A O 1 ATOM 6664 C CB . VAL A 1 834 ? -33.173 30.014 34.021 1.00 44.29 ? 834 VAL A CB 1 ATOM 6665 C CG1 . VAL A 1 834 ? -33.791 31.001 33.015 1.00 44.44 ? 834 VAL A CG1 1 ATOM 6666 C CG2 . VAL A 1 834 ? -32.687 30.740 35.262 1.00 44.70 ? 834 VAL A CG2 1 ATOM 6667 N N . PRO A 1 835 ? -36.125 28.476 32.974 1.00 45.99 ? 835 PRO A N 1 ATOM 6668 C CA . PRO A 1 835 ? -36.843 28.031 31.785 1.00 46.85 ? 835 PRO A CA 1 ATOM 6669 C C . PRO A 1 835 ? -36.070 28.419 30.518 1.00 47.83 ? 835 PRO A C 1 ATOM 6670 O O . PRO A 1 835 ? -35.308 29.381 30.570 1.00 48.52 ? 835 PRO A O 1 ATOM 6671 C CB . PRO A 1 835 ? -38.160 28.805 31.896 1.00 47.14 ? 835 PRO A CB 1 ATOM 6672 C CG . PRO A 1 835 ? -38.396 28.866 33.360 1.00 46.47 ? 835 PRO A CG 1 ATOM 6673 C CD . PRO A 1 835 ? -37.035 29.120 33.945 1.00 46.28 ? 835 PRO A CD 1 ATOM 6674 N N . SER A 1 836 ? -36.248 27.758 29.374 1.00 48.61 ? 836 SER A N 1 ATOM 6675 C CA . SER A 1 836 ? -37.356 26.873 28.984 1.00 49.72 ? 836 SER A CA 1 ATOM 6676 C C . SER A 1 836 ? -37.837 27.374 27.625 1.00 49.91 ? 836 SER A C 1 ATOM 6677 O O . SER A 1 836 ? -37.084 28.052 26.913 1.00 50.30 ? 836 SER A O 1 ATOM 6678 C CB . SER A 1 836 ? -38.522 26.851 29.977 1.00 50.05 ? 836 SER A CB 1 ATOM 6679 O OG . SER A 1 836 ? -39.245 25.640 29.880 1.00 50.85 ? 836 SER A OG 1 ATOM 6680 N N . THR A 1 838 ? -38.441 27.189 24.275 1.00 43.64 ? 838 THR A N 1 ATOM 6681 C CA . THR A 1 838 ? -38.298 25.994 23.434 1.00 43.34 ? 838 THR A CA 1 ATOM 6682 C C . THR A 1 838 ? -38.937 24.737 24.055 1.00 41.65 ? 838 THR A C 1 ATOM 6683 O O . THR A 1 838 ? -38.758 24.454 25.233 1.00 42.67 ? 838 THR A O 1 ATOM 6684 C CB . THR A 1 838 ? -36.815 25.701 23.100 1.00 43.53 ? 838 THR A CB 1 ATOM 6685 O OG1 . THR A 1 838 ? -36.092 25.443 24.310 1.00 45.54 ? 838 THR A OG1 1 ATOM 6686 C CG2 . THR A 1 838 ? -36.169 26.885 22.348 1.00 44.94 ? 838 THR A CG2 1 ATOM 6687 N N . SER A 1 839 ? -39.705 24.019 23.245 1.00 39.43 ? 839 SER A N 1 ATOM 6688 C CA . SER A 1 839 ? -40.379 22.783 23.633 1.00 36.78 ? 839 SER A CA 1 ATOM 6689 C C . SER A 1 839 ? -39.643 21.667 22.885 1.00 33.73 ? 839 SER A C 1 ATOM 6690 O O . SER A 1 839 ? -39.474 21.770 21.665 1.00 34.20 ? 839 SER A O 1 ATOM 6691 C CB . SER A 1 839 ? -41.839 22.854 23.176 1.00 37.40 ? 839 SER A CB 1 ATOM 6692 O OG . SER A 1 839 ? -42.640 21.816 23.727 1.00 39.72 ? 839 SER A OG 1 ATOM 6693 N N . PRO A 1 840 ? -39.147 20.626 23.600 1.00 30.73 ? 840 PRO A N 1 ATOM 6694 C CA . PRO A 1 840 ? -38.492 19.563 22.837 1.00 27.81 ? 840 PRO A CA 1 ATOM 6695 C C . PRO A 1 840 ? -39.515 18.712 22.103 1.00 25.99 ? 840 PRO A C 1 ATOM 6696 O O . PRO A 1 840 ? -40.701 18.789 22.404 1.00 25.36 ? 840 PRO A O 1 ATOM 6697 C CB . PRO A 1 840 ? -37.790 18.731 23.904 1.00 27.98 ? 840 PRO A CB 1 ATOM 6698 C CG . PRO A 1 840 ? -38.544 18.989 25.151 1.00 30.50 ? 840 PRO A CG 1 ATOM 6699 C CD . PRO A 1 840 ? -39.107 20.372 25.053 1.00 29.96 ? 840 PRO A CD 1 ATOM 6700 N N . THR A 1 841 ? -39.051 17.915 21.146 1.00 23.05 ? 841 THR A N 1 ATOM 6701 C CA . THR A 1 841 ? -39.902 16.939 20.431 1.00 21.46 ? 841 THR A CA 1 ATOM 6702 C C . THR A 1 841 ? -40.027 15.643 21.216 1.00 20.93 ? 841 THR A C 1 ATOM 6703 O O . THR A 1 841 ? -39.029 15.113 21.688 1.00 20.18 ? 841 THR A O 1 ATOM 6704 C CB . THR A 1 841 ? -39.303 16.666 19.010 1.00 21.08 ? 841 THR A CB 1 ATOM 6705 O OG1 . THR A 1 841 ? -39.340 17.869 18.251 1.00 20.04 ? 841 THR A OG1 1 ATOM 6706 C CG2 . THR A 1 841 ? -40.011 15.534 18.257 1.00 20.23 ? 841 THR A CG2 1 ATOM 6707 N N . VAL A 1 842 ? -41.255 15.128 21.374 1.00 20.07 ? 842 VAL A N 1 ATOM 6708 C CA . VAL A 1 842 ? -41.450 13.886 22.093 1.00 20.40 ? 842 VAL A CA 1 ATOM 6709 C C . VAL A 1 842 ? -42.212 12.924 21.211 1.00 20.30 ? 842 VAL A C 1 ATOM 6710 O O . VAL A 1 842 ? -43.271 13.293 20.632 1.00 18.81 ? 842 VAL A O 1 ATOM 6711 C CB . VAL A 1 842 ? -42.232 14.077 23.442 1.00 21.93 ? 842 VAL A CB 1 ATOM 6712 C CG1 . VAL A 1 842 ? -42.493 12.706 24.110 1.00 23.19 ? 842 VAL A CG1 1 ATOM 6713 C CG2 . VAL A 1 842 ? -41.491 15.027 24.362 1.00 23.56 ? 842 VAL A CG2 1 ATOM 6714 N N . THR A 1 843 ? -41.632 11.736 21.046 1.00 18.65 ? 843 THR A N 1 ATOM 6715 C CA . THR A 1 843 ? -42.265 10.616 20.348 1.00 19.20 ? 843 THR A CA 1 ATOM 6716 C C . THR A 1 843 ? -42.610 9.526 21.349 1.00 18.98 ? 843 THR A C 1 ATOM 6717 O O . THR A 1 843 ? -41.803 9.174 22.212 1.00 18.40 ? 843 THR A O 1 ATOM 6718 C CB . THR A 1 843 ? -41.348 10.099 19.253 1.00 19.78 ? 843 THR A CB 1 ATOM 6719 O OG1 . THR A 1 843 ? -40.896 11.213 18.464 1.00 19.40 ? 843 THR A OG1 1 ATOM 6720 C CG2 . THR A 1 843 ? -42.040 9.100 18.365 1.00 18.50 ? 843 THR A CG2 1 ATOM 6721 N N . TYR A 1 844 ? -43.829 8.993 21.253 1.00 18.82 ? 844 TYR A N 1 ATOM 6722 C CA . TYR A 1 844 ? -44.243 8.015 22.224 1.00 18.06 ? 844 TYR A CA 1 ATOM 6723 C C . TYR A 1 844 ? -44.804 6.761 21.562 1.00 18.62 ? 844 TYR A C 1 ATOM 6724 O O . TYR A 1 844 ? -45.601 6.826 20.608 1.00 17.75 ? 844 TYR A O 1 ATOM 6725 C CB . TYR A 1 844 ? -45.253 8.633 23.228 1.00 19.10 ? 844 TYR A CB 1 ATOM 6726 C CG . TYR A 1 844 ? -45.612 7.681 24.351 1.00 18.50 ? 844 TYR A CG 1 ATOM 6727 C CD1 . TYR A 1 844 ? -44.656 7.289 25.291 1.00 18.41 ? 844 TYR A CD1 1 ATOM 6728 C CD2 . TYR A 1 844 ? -46.914 7.154 24.463 1.00 19.86 ? 844 TYR A CD2 1 ATOM 6729 C CE1 . TYR A 1 844 ? -44.967 6.387 26.311 1.00 15.88 ? 844 TYR A CE1 1 ATOM 6730 C CE2 . TYR A 1 844 ? -47.237 6.279 25.465 1.00 16.89 ? 844 TYR A CE2 1 ATOM 6731 C CZ . TYR A 1 844 ? -46.271 5.895 26.393 1.00 18.71 ? 844 TYR A CZ 1 ATOM 6732 O OH . TYR A 1 844 ? -46.616 5.025 27.393 1.00 20.53 ? 844 TYR A OH 1 ATOM 6733 N N . ASP A 1 845 ? -44.348 5.612 22.062 1.00 18.63 ? 845 ASP A N 1 ATOM 6734 C CA . ASP A 1 845 ? -44.831 4.320 21.648 1.00 19.83 ? 845 ASP A CA 1 ATOM 6735 C C . ASP A 1 845 ? -45.699 3.777 22.791 1.00 20.83 ? 845 ASP A C 1 ATOM 6736 O O . ASP A 1 845 ? -45.198 3.313 23.810 1.00 19.54 ? 845 ASP A O 1 ATOM 6737 C CB . ASP A 1 845 ? -43.653 3.379 21.366 1.00 20.23 ? 845 ASP A CB 1 ATOM 6738 C CG . ASP A 1 845 ? -44.081 2.074 20.718 1.00 22.60 ? 845 ASP A CG 1 ATOM 6739 O OD1 . ASP A 1 845 ? -45.175 1.527 21.047 1.00 24.55 ? 845 ASP A OD1 1 ATOM 6740 O OD2 . ASP A 1 845 ? -43.317 1.566 19.881 1.00 26.44 ? 845 ASP A OD2 1 ATOM 6741 N N . SER A 1 846 ? -47.012 3.814 22.622 1.00 22.50 ? 846 SER A N 1 ATOM 6742 C CA . SER A 1 846 ? -47.887 3.357 23.696 1.00 24.47 ? 846 SER A CA 1 ATOM 6743 C C . SER A 1 846 ? -47.946 1.835 23.918 1.00 24.41 ? 846 SER A C 1 ATOM 6744 O O . SER A 1 846 ? -48.297 1.407 25.034 1.00 25.74 ? 846 SER A O 1 ATOM 6745 C CB . SER A 1 846 ? -49.305 3.882 23.459 1.00 24.71 ? 846 SER A CB 1 ATOM 6746 O OG . SER A 1 846 ? -49.843 3.099 22.419 1.00 27.55 ? 846 SER A OG 1 ATOM 6747 N N . ASN A 1 847 ? -47.651 1.022 22.901 1.00 24.65 ? 847 ASN A N 1 ATOM 6748 C CA . ASN A 1 847 ? -47.563 -0.444 23.076 1.00 24.73 ? 847 ASN A CA 1 ATOM 6749 C C . ASN A 1 847 ? -46.306 -0.826 23.885 1.00 24.07 ? 847 ASN A C 1 ATOM 6750 O O . ASN A 1 847 ? -46.361 -1.703 24.752 1.00 24.43 ? 847 ASN A O 1 ATOM 6751 C CB . ASN A 1 847 ? -47.547 -1.219 21.746 1.00 25.72 ? 847 ASN A CB 1 ATOM 6752 C CG . ASN A 1 847 ? -47.697 -2.769 21.944 1.00 28.90 ? 847 ASN A CG 1 ATOM 6753 O OD1 . ASN A 1 847 ? -46.833 -3.563 21.511 1.00 35.93 ? 847 ASN A OD1 1 ATOM 6754 N ND2 . ASN A 1 847 ? -48.781 -3.188 22.622 1.00 34.81 ? 847 ASN A ND2 1 ATOM 6755 N N . LEU A 1 848 ? -45.187 -0.159 23.606 1.00 22.88 ? 848 LEU A N 1 ATOM 6756 C CA . LEU A 1 848 ? -43.912 -0.493 24.252 1.00 22.16 ? 848 LEU A CA 1 ATOM 6757 C C . LEU A 1 848 ? -43.616 0.302 25.525 1.00 19.93 ? 848 LEU A C 1 ATOM 6758 O O . LEU A 1 848 ? -42.677 -0.025 26.266 1.00 18.04 ? 848 LEU A O 1 ATOM 6759 C CB . LEU A 1 848 ? -42.767 -0.264 23.241 1.00 23.06 ? 848 LEU A CB 1 ATOM 6760 C CG . LEU A 1 848 ? -42.312 -1.468 22.409 1.00 25.60 ? 848 LEU A CG 1 ATOM 6761 C CD1 . LEU A 1 848 ? -43.427 -2.444 22.031 1.00 28.82 ? 848 LEU A CD1 1 ATOM 6762 C CD2 . LEU A 1 848 ? -41.534 -1.010 21.204 1.00 25.08 ? 848 LEU A CD2 1 ATOM 6763 N N . LYS A 1 849 ? -44.392 1.361 25.760 1.00 16.94 ? 849 LYS A N 1 ATOM 6764 C CA . LYS A 1 849 ? -44.189 2.314 26.867 1.00 15.75 ? 849 LYS A CA 1 ATOM 6765 C C . LYS A 1 849 ? -42.770 2.951 26.793 1.00 15.50 ? 849 LYS A C 1 ATOM 6766 O O . LYS A 1 849 ? -42.081 3.034 27.784 1.00 14.46 ? 849 LYS A O 1 ATOM 6767 C CB . LYS A 1 849 ? -44.429 1.677 28.244 1.00 16.23 ? 849 LYS A CB 1 ATOM 6768 C CG . LYS A 1 849 ? -45.772 0.909 28.350 1.00 17.87 ? 849 LYS A CG 1 ATOM 6769 C CD . LYS A 1 849 ? -46.892 1.892 28.276 1.00 17.12 ? 849 LYS A CD 1 ATOM 6770 C CE . LYS A 1 849 ? -48.266 1.249 28.610 1.00 22.44 ? 849 LYS A CE 1 ATOM 6771 N NZ . LYS A 1 849 ? -49.359 2.258 28.493 1.00 25.92 ? 849 LYS A NZ 1 ATOM 6772 N N . VAL A 1 850 ? -42.403 3.390 25.602 1.00 15.58 ? 850 VAL A N 1 ATOM 6773 C CA . VAL A 1 850 ? -41.113 4.102 25.343 1.00 15.99 ? 850 VAL A CA 1 ATOM 6774 C C . VAL A 1 850 ? -41.407 5.516 24.836 1.00 16.31 ? 850 VAL A C 1 ATOM 6775 O O . VAL A 1 850 ? -42.169 5.683 23.844 1.00 17.27 ? 850 VAL A O 1 ATOM 6776 C CB . VAL A 1 850 ? -40.327 3.358 24.295 1.00 15.24 ? 850 VAL A CB 1 ATOM 6777 C CG1 . VAL A 1 850 ? -38.952 4.072 23.996 1.00 16.72 ? 850 VAL A CG1 1 ATOM 6778 C CG2 . VAL A 1 850 ? -40.118 1.888 24.744 1.00 15.76 ? 850 VAL A CG2 1 ATOM 6779 N N . ALA A 1 851 ? -40.769 6.511 25.472 1.00 15.42 ? 851 ALA A N 1 ATOM 6780 C CA . ALA A 1 851 ? -40.795 7.889 25.029 1.00 15.39 ? 851 ALA A CA 1 ATOM 6781 C C . ALA A 1 851 ? -39.385 8.229 24.572 1.00 16.70 ? 851 ALA A C 1 ATOM 6782 O O . ALA A 1 851 ? -38.430 7.772 25.196 1.00 15.87 ? 851 ALA A O 1 ATOM 6783 C CB . ALA A 1 851 ? -41.144 8.770 26.153 1.00 14.77 ? 851 ALA A CB 1 ATOM 6784 N N . ILE A 1 852 ? -39.276 8.983 23.486 1.00 16.14 ? 852 ILE A N 1 ATOM 6785 C CA . ILE A 1 852 ? -37.979 9.567 23.096 1.00 16.95 ? 852 ILE A CA 1 ATOM 6786 C C . ILE A 1 852 ? -38.115 11.063 22.962 1.00 17.18 ? 852 ILE A C 1 ATOM 6787 O O . ILE A 1 852 ? -38.995 11.562 22.238 1.00 18.30 ? 852 ILE A O 1 ATOM 6788 C CB . ILE A 1 852 ? -37.438 8.973 21.801 1.00 16.45 ? 852 ILE A CB 1 ATOM 6789 C CG1 . ILE A 1 852 ? -37.464 7.437 21.870 1.00 18.42 ? 852 ILE A CG1 1 ATOM 6790 C CG2 . ILE A 1 852 ? -35.989 9.559 21.519 1.00 17.24 ? 852 ILE A CG2 1 ATOM 6791 C CD1 . ILE A 1 852 ? -36.870 6.731 20.628 1.00 19.78 ? 852 ILE A CD1 1 ATOM 6792 N N . ILE A 1 853 ? -37.248 11.784 23.661 1.00 17.40 ? 853 ILE A N 1 ATOM 6793 C CA . ILE A 1 853 ? -37.238 13.231 23.638 1.00 18.19 ? 853 ILE A CA 1 ATOM 6794 C C . ILE A 1 853 ? -36.112 13.618 22.712 1.00 19.62 ? 853 ILE A C 1 ATOM 6795 O O . ILE A 1 853 ? -34.955 13.181 22.901 1.00 17.60 ? 853 ILE A O 1 ATOM 6796 C CB . ILE A 1 853 ? -37.032 13.822 25.035 1.00 18.44 ? 853 ILE A CB 1 ATOM 6797 C CG1 . ILE A 1 853 ? -38.183 13.358 25.975 1.00 19.52 ? 853 ILE A CG1 1 ATOM 6798 C CG2 . ILE A 1 853 ? -36.975 15.355 24.970 1.00 19.49 ? 853 ILE A CG2 1 ATOM 6799 C CD1 . ILE A 1 853 ? -37.972 13.718 27.404 1.00 21.60 ? 853 ILE A CD1 1 ATOM 6800 N N . THR A 1 854 ? -36.457 14.392 21.687 1.00 19.86 ? 854 THR A N 1 ATOM 6801 C CA . THR A 1 854 ? -35.449 14.924 20.762 1.00 21.63 ? 854 THR A CA 1 ATOM 6802 C C . THR A 1 854 ? -35.592 16.448 20.607 1.00 21.75 ? 854 THR A C 1 ATOM 6803 O O . THR A 1 854 ? -36.379 17.082 21.323 1.00 19.66 ? 854 THR A O 1 ATOM 6804 C CB . THR A 1 854 ? -35.505 14.238 19.379 1.00 22.04 ? 854 THR A CB 1 ATOM 6805 O OG1 . THR A 1 854 ? -36.838 14.268 18.849 1.00 20.98 ? 854 THR A OG1 1 ATOM 6806 C CG2 . THR A 1 854 ? -35.028 12.789 19.457 1.00 23.20 ? 854 THR A CG2 1 ATOM 6807 N N . ASP A 1 855 ? -34.843 17.029 19.659 1.00 23.08 ? 855 ASP A N 1 ATOM 6808 C CA . ASP A 1 855 ? -34.811 18.490 19.479 1.00 24.56 ? 855 ASP A CA 1 ATOM 6809 C C . ASP A 1 855 ? -34.514 19.162 20.825 1.00 24.83 ? 855 ASP A C 1 ATOM 6810 O O . ASP A 1 855 ? -35.219 20.074 21.294 1.00 23.92 ? 855 ASP A O 1 ATOM 6811 C CB . ASP A 1 855 ? -36.094 19.011 18.811 1.00 25.38 ? 855 ASP A CB 1 ATOM 6812 C CG . ASP A 1 855 ? -35.995 20.488 18.409 1.00 29.10 ? 855 ASP A CG 1 ATOM 6813 O OD1 . ASP A 1 855 ? -34.865 21.007 18.204 1.00 33.47 ? 855 ASP A OD1 1 ATOM 6814 O OD2 . ASP A 1 855 ? -37.054 21.164 18.348 1.00 32.32 ? 855 ASP A OD2 1 ATOM 6815 N N . ILE A 1 856 ? -33.458 18.650 21.448 1.00 24.44 ? 856 ILE A N 1 ATOM 6816 C CA . ILE A 1 856 ? -32.979 19.083 22.745 1.00 25.70 ? 856 ILE A CA 1 ATOM 6817 C C . ILE A 1 856 ? -31.449 19.171 22.595 1.00 24.71 ? 856 ILE A C 1 ATOM 6818 O O . ILE A 1 856 ? -30.885 18.492 21.751 1.00 25.14 ? 856 ILE A O 1 ATOM 6819 C CB . ILE A 1 856 ? -33.457 18.069 23.848 1.00 26.17 ? 856 ILE A CB 1 ATOM 6820 C CG1 . ILE A 1 856 ? -33.568 18.701 25.234 1.00 28.48 ? 856 ILE A CG1 1 ATOM 6821 C CG2 . ILE A 1 856 ? -32.625 16.784 23.854 1.00 27.70 ? 856 ILE A CG2 1 ATOM 6822 C CD1 . ILE A 1 856 ? -34.385 17.835 26.249 1.00 28.22 ? 856 ILE A CD1 1 ATOM 6823 N N . ASP A 1 857 ? -30.803 20.016 23.385 1.00 23.79 ? 857 ASP A N 1 ATOM 6824 C CA . ASP A 1 857 ? -29.344 20.204 23.315 1.00 25.05 ? 857 ASP A CA 1 ATOM 6825 C C . ASP A 1 857 ? -28.896 20.483 24.751 1.00 22.72 ? 857 ASP A C 1 ATOM 6826 O O . ASP A 1 857 ? -28.786 21.634 25.166 1.00 23.65 ? 857 ASP A O 1 ATOM 6827 C CB . ASP A 1 857 ? -29.044 21.380 22.363 1.00 25.72 ? 857 ASP A CB 1 ATOM 6828 C CG . ASP A 1 857 ? -27.564 21.684 22.213 1.00 30.25 ? 857 ASP A CG 1 ATOM 6829 O OD1 . ASP A 1 857 ? -26.787 20.806 21.778 1.00 32.78 ? 857 ASP A OD1 1 ATOM 6830 O OD2 . ASP A 1 857 ? -27.201 22.843 22.490 1.00 36.14 ? 857 ASP A OD2 1 ATOM 6831 N N . LEU A 1 858 ? -28.695 19.438 25.546 1.00 20.50 ? 858 LEU A N 1 ATOM 6832 C CA . LEU A 1 858 ? -28.260 19.650 26.920 1.00 19.05 ? 858 LEU A CA 1 ATOM 6833 C C . LEU A 1 858 ? -26.754 19.593 26.957 1.00 19.79 ? 858 LEU A C 1 ATOM 6834 O O . LEU A 1 858 ? -26.190 18.503 26.842 1.00 19.27 ? 858 LEU A O 1 ATOM 6835 C CB . LEU A 1 858 ? -28.833 18.582 27.850 1.00 19.05 ? 858 LEU A CB 1 ATOM 6836 C CG . LEU A 1 858 ? -30.357 18.346 27.740 1.00 20.43 ? 858 LEU A CG 1 ATOM 6837 C CD1 . LEU A 1 858 ? -30.780 17.407 28.807 1.00 20.26 ? 858 LEU A CD1 1 ATOM 6838 C CD2 . LEU A 1 858 ? -31.091 19.677 27.848 1.00 22.06 ? 858 LEU A CD2 1 ATOM 6839 N N . LEU A 1 859 ? -26.094 20.735 27.109 1.00 18.13 ? 859 LEU A N 1 ATOM 6840 C CA . LEU A 1 859 ? -24.636 20.737 26.939 1.00 18.42 ? 859 LEU A CA 1 ATOM 6841 C C . LEU A 1 859 ? -23.949 19.899 28.019 1.00 18.32 ? 859 LEU A C 1 ATOM 6842 O O . LEU A 1 859 ? -24.251 19.983 29.206 1.00 15.49 ? 859 LEU A O 1 ATOM 6843 C CB . LEU A 1 859 ? -24.092 22.170 26.966 1.00 18.23 ? 859 LEU A CB 1 ATOM 6844 C CG . LEU A 1 859 ? -24.723 23.207 26.029 1.00 19.90 ? 859 LEU A CG 1 ATOM 6845 C CD1 . LEU A 1 859 ? -24.032 24.574 26.319 1.00 20.05 ? 859 LEU A CD1 1 ATOM 6846 C CD2 . LEU A 1 859 ? -24.617 22.790 24.556 1.00 21.83 ? 859 LEU A CD2 1 ATOM 6847 N N . LEU A 1 860 ? -23.004 19.075 27.578 1.00 20.15 ? 860 LEU A N 1 ATOM 6848 C CA . LEU A 1 860 ? -22.187 18.338 28.491 1.00 21.96 ? 860 LEU A CA 1 ATOM 6849 C C . LEU A 1 860 ? -21.501 19.298 29.439 1.00 22.98 ? 860 LEU A C 1 ATOM 6850 O O . LEU A 1 860 ? -20.872 20.286 29.023 1.00 24.47 ? 860 LEU A O 1 ATOM 6851 C CB . LEU A 1 860 ? -21.156 17.515 27.694 1.00 22.37 ? 860 LEU A CB 1 ATOM 6852 C CG . LEU A 1 860 ? -20.376 16.492 28.475 1.00 23.00 ? 860 LEU A CG 1 ATOM 6853 C CD1 . LEU A 1 860 ? -21.259 15.366 28.972 1.00 22.87 ? 860 LEU A CD1 1 ATOM 6854 C CD2 . LEU A 1 860 ? -19.259 15.996 27.570 1.00 24.09 ? 860 LEU A CD2 1 ATOM 6855 N N . GLY A 1 861 ? -21.652 19.036 30.723 1.00 22.05 ? 861 GLY A N 1 ATOM 6856 C CA . GLY A 1 861 ? -21.016 19.877 31.711 1.00 22.81 ? 861 GLY A CA 1 ATOM 6857 C C . GLY A 1 861 ? -21.896 20.952 32.311 1.00 22.71 ? 861 GLY A C 1 ATOM 6858 O O . GLY A 1 861 ? -21.429 21.702 33.145 1.00 23.62 ? 861 GLY A O 1 ATOM 6859 N N . GLU A 1 862 ? -23.168 21.019 31.899 1.00 22.21 ? 862 GLU A N 1 ATOM 6860 C CA . GLU A 1 862 ? -24.132 22.016 32.409 1.00 21.77 ? 862 GLU A CA 1 ATOM 6861 C C . GLU A 1 862 ? -25.261 21.293 33.169 1.00 21.84 ? 862 GLU A C 1 ATOM 6862 O O . GLU A 1 862 ? -25.598 20.166 32.855 1.00 20.49 ? 862 GLU A O 1 ATOM 6863 C CB . GLU A 1 862 ? -24.780 22.830 31.262 1.00 22.44 ? 862 GLU A CB 1 ATOM 6864 C CG . GLU A 1 862 ? -23.907 23.867 30.565 1.00 24.95 ? 862 GLU A CG 1 ATOM 6865 C CD . GLU A 1 862 ? -23.304 24.856 31.538 1.00 29.87 ? 862 GLU A CD 1 ATOM 6866 O OE1 . GLU A 1 862 ? -24.080 25.561 32.231 1.00 33.43 ? 862 GLU A OE1 1 ATOM 6867 O OE2 . GLU A 1 862 ? -22.056 24.946 31.596 1.00 32.92 ? 862 GLU A OE2 1 ATOM 6868 N N . ALA A 1 863 ? -25.841 21.979 34.142 1.00 20.79 ? 863 ALA A N 1 ATOM 6869 C CA . ALA A 1 863 ? -26.913 21.442 34.974 1.00 20.96 ? 863 ALA A CA 1 ATOM 6870 C C . ALA A 1 863 ? -28.236 21.721 34.303 1.00 20.45 ? 863 ALA A C 1 ATOM 6871 O O . ALA A 1 863 ? -28.486 22.841 33.850 1.00 19.47 ? 863 ALA A O 1 ATOM 6872 C CB . ALA A 1 863 ? -26.883 22.106 36.325 1.00 21.71 ? 863 ALA A CB 1 ATOM 6873 N N . TYR A 1 864 ? -29.097 20.713 34.266 1.00 20.99 ? 864 TYR A N 1 ATOM 6874 C CA . TYR A 1 864 ? -30.400 20.870 33.656 1.00 20.78 ? 864 TYR A CA 1 ATOM 6875 C C . TYR A 1 864 ? -31.425 20.135 34.495 1.00 21.67 ? 864 TYR A C 1 ATOM 6876 O O . TYR A 1 864 ? -31.090 19.230 35.250 1.00 20.00 ? 864 TYR A O 1 ATOM 6877 C CB . TYR A 1 864 ? -30.430 20.274 32.254 1.00 20.18 ? 864 TYR A CB 1 ATOM 6878 C CG . TYR A 1 864 ? -29.581 21.015 31.252 1.00 19.88 ? 864 TYR A CG 1 ATOM 6879 C CD1 . TYR A 1 864 ? -30.078 22.134 30.573 1.00 19.88 ? 864 TYR A CD1 1 ATOM 6880 C CD2 . TYR A 1 864 ? -28.284 20.575 30.962 1.00 19.54 ? 864 TYR A CD2 1 ATOM 6881 C CE1 . TYR A 1 864 ? -29.285 22.818 29.657 1.00 19.73 ? 864 TYR A CE1 1 ATOM 6882 C CE2 . TYR A 1 864 ? -27.480 21.270 30.052 1.00 16.71 ? 864 TYR A CE2 1 ATOM 6883 C CZ . TYR A 1 864 ? -27.980 22.362 29.409 1.00 19.86 ? 864 TYR A CZ 1 ATOM 6884 O OH . TYR A 1 864 ? -27.194 23.021 28.514 1.00 18.36 ? 864 TYR A OH 1 ATOM 6885 N N . THR A 1 865 ? -32.670 20.572 34.351 1.00 22.43 ? 865 THR A N 1 ATOM 6886 C CA . THR A 1 865 ? -33.816 19.823 34.839 1.00 24.93 ? 865 THR A CA 1 ATOM 6887 C C . THR A 1 865 ? -34.767 19.627 33.667 1.00 25.00 ? 865 THR A C 1 ATOM 6888 O O . THR A 1 865 ? -35.106 20.595 32.993 1.00 26.32 ? 865 THR A O 1 ATOM 6889 C CB . THR A 1 865 ? -34.542 20.609 35.952 1.00 25.28 ? 865 THR A CB 1 ATOM 6890 O OG1 . THR A 1 865 ? -33.629 20.862 37.031 1.00 28.01 ? 865 THR A OG1 1 ATOM 6891 C CG2 . THR A 1 865 ? -35.720 19.785 36.494 1.00 26.57 ? 865 THR A CG2 1 ATOM 6892 N N . VAL A 1 866 ? -35.181 18.388 33.397 1.00 24.74 ? 866 VAL A N 1 ATOM 6893 C CA . VAL A 1 866 ? -36.186 18.146 32.376 1.00 23.98 ? 866 VAL A CA 1 ATOM 6894 C C . VAL A 1 866 ? -37.394 17.617 33.147 1.00 24.38 ? 866 VAL A C 1 ATOM 6895 O O . VAL A 1 866 ? -37.270 16.663 33.904 1.00 23.47 ? 866 VAL A O 1 ATOM 6896 C CB . VAL A 1 866 ? -35.705 17.160 31.295 1.00 23.11 ? 866 VAL A CB 1 ATOM 6897 C CG1 . VAL A 1 866 ? -36.767 16.951 30.200 1.00 23.35 ? 866 VAL A CG1 1 ATOM 6898 C CG2 . VAL A 1 866 ? -34.387 17.673 30.654 1.00 22.11 ? 866 VAL A CG2 1 ATOM 6899 N N . GLU A 1 867 ? -38.535 18.280 32.990 1.00 24.40 ? 867 GLU A N 1 ATOM 6900 C CA . GLU A 1 867 ? -39.705 17.920 33.772 1.00 26.36 ? 867 GLU A CA 1 ATOM 6901 C C . GLU A 1 867 ? -40.803 17.597 32.787 1.00 25.08 ? 867 GLU A C 1 ATOM 6902 O O . GLU A 1 867 ? -40.827 18.142 31.689 1.00 24.09 ? 867 GLU A O 1 ATOM 6903 C CB . GLU A 1 867 ? -40.146 19.074 34.669 1.00 25.96 ? 867 GLU A CB 1 ATOM 6904 C CG . GLU A 1 867 ? -39.195 19.396 35.834 1.00 30.52 ? 867 GLU A CG 1 ATOM 6905 C CD . GLU A 1 867 ? -39.597 20.676 36.560 1.00 30.90 ? 867 GLU A CD 1 ATOM 6906 O OE1 . GLU A 1 867 ? -38.797 21.630 36.598 1.00 34.44 ? 867 GLU A OE1 1 ATOM 6907 O OE2 . GLU A 1 867 ? -40.740 20.721 37.068 1.00 38.05 ? 867 GLU A OE2 1 ATOM 6908 N N . TRP A 1 868 ? -41.697 16.704 33.176 1.00 26.47 ? 868 TRP A N 1 ATOM 6909 C CA . TRP A 1 868 ? -42.842 16.399 32.345 1.00 28.31 ? 868 TRP A CA 1 ATOM 6910 C C . TRP A 1 868 ? -44.039 16.103 33.239 1.00 29.55 ? 868 TRP A C 1 ATOM 6911 O O . TRP A 1 868 ? -43.882 15.961 34.443 1.00 28.91 ? 868 TRP A O 1 ATOM 6912 C CB . TRP A 1 868 ? -42.536 15.222 31.410 1.00 27.76 ? 868 TRP A CB 1 ATOM 6913 C CG . TRP A 1 868 ? -42.118 13.950 32.074 1.00 28.57 ? 868 TRP A CG 1 ATOM 6914 C CD1 . TRP A 1 868 ? -42.932 12.921 32.464 1.00 28.38 ? 868 TRP A CD1 1 ATOM 6915 C CD2 . TRP A 1 868 ? -40.777 13.544 32.387 1.00 28.14 ? 868 TRP A CD2 1 ATOM 6916 N NE1 . TRP A 1 868 ? -42.177 11.909 33.014 1.00 29.14 ? 868 TRP A NE1 1 ATOM 6917 C CE2 . TRP A 1 868 ? -40.856 12.275 32.990 1.00 28.61 ? 868 TRP A CE2 1 ATOM 6918 C CE3 . TRP A 1 868 ? -39.517 14.147 32.232 1.00 28.32 ? 868 TRP A CE3 1 ATOM 6919 C CZ2 . TRP A 1 868 ? -39.717 11.572 33.421 1.00 29.18 ? 868 TRP A CZ2 1 ATOM 6920 C CZ3 . TRP A 1 868 ? -38.386 13.450 32.663 1.00 27.22 ? 868 TRP A CZ3 1 ATOM 6921 C CH2 . TRP A 1 868 ? -38.499 12.182 33.255 1.00 28.16 ? 868 TRP A CH2 1 ATOM 6922 N N . ALA A 1 869 ? -45.226 16.054 32.639 1.00 31.65 ? 869 ALA A N 1 ATOM 6923 C CA . ALA A 1 869 ? -46.437 15.587 33.310 1.00 33.11 ? 869 ALA A CA 1 ATOM 6924 C C . ALA A 1 869 ? -46.931 14.296 32.650 1.00 34.58 ? 869 ALA A C 1 ATOM 6925 O O . ALA A 1 869 ? -46.368 13.846 31.642 1.00 33.96 ? 869 ALA A O 1 ATOM 6926 C CB . ALA A 1 869 ? -47.498 16.652 33.253 1.00 33.64 ? 869 ALA A CB 1 ATOM 6927 N N . HIS A 1 870 ? -47.970 13.690 33.231 1.00 35.66 ? 870 HIS A N 1 ATOM 6928 C CA . HIS A 1 870 ? -48.567 12.454 32.712 1.00 37.30 ? 870 HIS A CA 1 ATOM 6929 C C . HIS A 1 870 ? -50.082 12.634 32.551 1.00 38.17 ? 870 HIS A C 1 ATOM 6930 O O . HIS A 1 870 ? -50.581 12.755 31.428 1.00 39.12 ? 870 HIS A O 1 ATOM 6931 C CB . HIS A 1 870 ? -48.313 11.263 33.638 1.00 37.73 ? 870 HIS A CB 1 ATOM 6932 C CG . HIS A 1 870 ? -46.882 10.811 33.697 1.00 38.86 ? 870 HIS A CG 1 ATOM 6933 N ND1 . HIS A 1 870 ? -46.277 10.105 32.679 1.00 39.63 ? 870 HIS A ND1 1 ATOM 6934 C CD2 . HIS A 1 870 ? -45.958 10.915 34.679 1.00 40.73 ? 870 HIS A CD2 1 ATOM 6935 C CE1 . HIS A 1 870 ? -45.032 9.823 33.018 1.00 40.61 ? 870 HIS A CE1 1 ATOM 6936 N NE2 . HIS A 1 870 ? -44.812 10.302 34.228 1.00 41.08 ? 870 HIS A NE2 1 HETATM 6937 O OAA . NR3 B 2 . ? 3.852 -25.949 20.856 1.00 45.87 ? 1001 NR3 A OAA 1 HETATM 6938 O OAB . NR3 B 2 . ? 3.707 -14.018 18.514 1.00 20.36 ? 1001 NR3 A OAB 1 HETATM 6939 O OAC . NR3 B 2 . ? 5.325 -22.748 21.424 1.00 44.70 ? 1001 NR3 A OAC 1 HETATM 6940 O OAD . NR3 B 2 . ? -0.985 -14.590 20.757 1.00 20.82 ? 1001 NR3 A OAD 1 HETATM 6941 O OAE . NR3 B 2 . ? 2.201 -18.747 22.666 1.00 22.97 ? 1001 NR3 A OAE 1 HETATM 6942 O OAF . NR3 B 2 . ? 1.734 -23.444 21.979 1.00 41.16 ? 1001 NR3 A OAF 1 HETATM 6943 O OAG . NR3 B 2 . ? 0.064 -14.620 18.080 1.00 22.46 ? 1001 NR3 A OAG 1 HETATM 6944 O OAH . NR3 B 2 . ? 4.271 -20.927 22.736 1.00 26.11 ? 1001 NR3 A OAH 1 HETATM 6945 O OAI . NR3 B 2 . ? 1.537 -20.454 18.166 1.00 26.12 ? 1001 NR3 A OAI 1 HETATM 6946 O OAJ . NR3 B 2 . ? 3.383 -21.984 17.725 1.00 28.30 ? 1001 NR3 A OAJ 1 HETATM 6947 O OAK . NR3 B 2 . ? 1.571 -22.576 19.185 1.00 28.04 ? 1001 NR3 A OAK 1 HETATM 6948 C CAL . NR3 B 2 . ? 4.424 -25.010 21.805 1.00 44.61 ? 1001 NR3 A CAL 1 HETATM 6949 C CAM . NR3 B 2 . ? 3.205 -15.275 18.017 1.00 19.03 ? 1001 NR3 A CAM 1 HETATM 6950 C CAN . NR3 B 2 . ? 1.156 -15.783 21.464 1.00 20.40 ? 1001 NR3 A CAN 1 HETATM 6951 C CAO . NR3 B 2 . ? 2.267 -18.226 20.292 1.00 21.75 ? 1001 NR3 A CAO 1 HETATM 6952 O OAP . NR3 B 2 . ? 3.131 -20.984 19.904 1.00 26.11 ? 1001 NR3 A OAP 1 HETATM 6953 C CAQ . NR3 B 2 . ? 4.111 -23.546 21.406 1.00 41.36 ? 1001 NR3 A CAQ 1 HETATM 6954 C CAR . NR3 B 2 . ? 0.145 -15.445 20.348 1.00 22.35 ? 1001 NR3 A CAR 1 HETATM 6955 C CAS . NR3 B 2 . ? 2.779 -19.129 21.414 1.00 23.44 ? 1001 NR3 A CAS 1 HETATM 6956 C CAT . NR3 B 2 . ? 3.027 -22.943 22.328 1.00 37.39 ? 1001 NR3 A CAT 1 HETATM 6957 C CAU . NR3 B 2 . ? 0.943 -14.778 19.203 1.00 19.80 ? 1001 NR3 A CAU 1 HETATM 6958 C CAV . NR3 B 2 . ? 2.974 -21.409 22.384 1.00 29.28 ? 1001 NR3 A CAV 1 HETATM 6959 C CAW . NR3 B 2 . ? 2.040 -15.819 18.859 1.00 21.25 ? 1001 NR3 A CAW 1 HETATM 6960 C CAX . NR3 B 2 . ? 2.472 -20.620 21.135 1.00 26.15 ? 1001 NR3 A CAX 1 HETATM 6961 S SAY . NR3 B 2 . ? 2.567 -16.460 20.486 1.00 23.38 ? 1001 NR3 A SAY 1 HETATM 6962 S SAZ . NR3 B 2 . ? 2.401 -21.503 18.760 1.00 26.87 ? 1001 NR3 A SAZ 1 HETATM 6963 C C1 . NAG C 3 . ? 24.940 -10.463 35.323 1.00 24.60 ? 2001 NAG A C1 1 HETATM 6964 C C2 . NAG C 3 . ? 24.784 -9.627 36.600 1.00 26.08 ? 2001 NAG A C2 1 HETATM 6965 C C3 . NAG C 3 . ? 25.409 -8.233 36.447 1.00 27.63 ? 2001 NAG A C3 1 HETATM 6966 C C4 . NAG C 3 . ? 26.860 -8.294 35.939 1.00 28.21 ? 2001 NAG A C4 1 HETATM 6967 C C5 . NAG C 3 . ? 26.888 -9.216 34.721 1.00 26.38 ? 2001 NAG A C5 1 HETATM 6968 C C6 . NAG C 3 . ? 28.302 -9.435 34.174 1.00 24.81 ? 2001 NAG A C6 1 HETATM 6969 C C7 . NAG C 3 . ? 22.928 -9.977 38.133 1.00 29.31 ? 2001 NAG A C7 1 HETATM 6970 C C8 . NAG C 3 . ? 21.484 -9.766 38.474 1.00 30.59 ? 2001 NAG A C8 1 HETATM 6971 N N2 . NAG C 3 . ? 23.378 -9.489 36.982 1.00 27.42 ? 2001 NAG A N2 1 HETATM 6972 O O3 . NAG C 3 . ? 25.344 -7.586 37.692 1.00 25.05 ? 2001 NAG A O3 1 HETATM 6973 O O4 . NAG C 3 . ? 27.314 -7.022 35.494 1.00 32.64 ? 2001 NAG A O4 1 HETATM 6974 O O5 . NAG C 3 . ? 26.322 -10.489 34.996 1.00 27.01 ? 2001 NAG A O5 1 HETATM 6975 O O6 . NAG C 3 . ? 28.224 -10.190 32.975 1.00 26.32 ? 2001 NAG A O6 1 HETATM 6976 O O7 . NAG C 3 . ? 23.628 -10.590 38.934 1.00 34.20 ? 2001 NAG A O7 1 HETATM 6977 C C1 . NAG D 3 . ? 27.760 -6.114 36.522 1.00 38.16 ? 2002 NAG A C1 1 HETATM 6978 C C2 . NAG D 3 . ? 29.220 -5.763 36.227 1.00 40.03 ? 2002 NAG A C2 1 HETATM 6979 C C3 . NAG D 3 . ? 29.761 -4.670 37.141 1.00 42.82 ? 2002 NAG A C3 1 HETATM 6980 C C4 . NAG D 3 . ? 28.836 -3.457 37.150 1.00 43.30 ? 2002 NAG A C4 1 HETATM 6981 C C5 . NAG D 3 . ? 27.360 -3.841 37.299 1.00 43.40 ? 2002 NAG A C5 1 HETATM 6982 C C6 . NAG D 3 . ? 26.496 -2.676 36.841 1.00 44.07 ? 2002 NAG A C6 1 HETATM 6983 C C7 . NAG D 3 . ? 30.851 -7.319 35.299 1.00 40.84 ? 2002 NAG A C7 1 HETATM 6984 C C8 . NAG D 3 . ? 31.614 -8.603 35.479 1.00 41.22 ? 2002 NAG A C8 1 HETATM 6985 N N2 . NAG D 3 . ? 30.048 -6.956 36.299 1.00 40.31 ? 2002 NAG A N2 1 HETATM 6986 O O3 . NAG D 3 . ? 31.045 -4.287 36.677 1.00 45.22 ? 2002 NAG A O3 1 HETATM 6987 O O4 . NAG D 3 . ? 29.202 -2.613 38.226 1.00 46.28 ? 2002 NAG A O4 1 HETATM 6988 O O5 . NAG D 3 . ? 26.967 -4.946 36.502 1.00 39.46 ? 2002 NAG A O5 1 HETATM 6989 O O6 . NAG D 3 . ? 25.258 -2.782 37.498 1.00 48.22 ? 2002 NAG A O6 1 HETATM 6990 O O7 . NAG D 3 . ? 30.982 -6.664 34.266 1.00 40.76 ? 2002 NAG A O7 1 HETATM 6991 C C1 . NAG E 3 . ? -17.336 9.447 11.351 1.00 32.37 ? 2003 NAG A C1 1 HETATM 6992 C C2 . NAG E 3 . ? -17.765 10.908 11.253 1.00 35.30 ? 2003 NAG A C2 1 HETATM 6993 C C3 . NAG E 3 . ? -17.428 11.511 9.875 1.00 36.37 ? 2003 NAG A C3 1 HETATM 6994 C C4 . NAG E 3 . ? -15.941 11.391 9.614 1.00 35.63 ? 2003 NAG A C4 1 HETATM 6995 C C5 . NAG E 3 . ? -15.553 9.913 9.740 1.00 36.57 ? 2003 NAG A C5 1 HETATM 6996 C C6 . NAG E 3 . ? -14.043 9.694 9.588 1.00 35.99 ? 2003 NAG A C6 1 HETATM 6997 C C7 . NAG E 3 . ? -19.814 11.710 12.350 1.00 41.66 ? 2003 NAG A C7 1 HETATM 6998 C C8 . NAG E 3 . ? -19.414 13.152 12.569 1.00 41.59 ? 2003 NAG A C8 1 HETATM 6999 N N2 . NAG E 3 . ? -19.193 10.995 11.420 1.00 37.86 ? 2003 NAG A N2 1 HETATM 7000 O O3 . NAG E 3 . ? -17.865 12.868 9.804 1.00 38.43 ? 2003 NAG A O3 1 HETATM 7001 O O4 . NAG E 3 . ? -15.650 11.879 8.326 1.00 39.95 ? 2003 NAG A O4 1 HETATM 7002 O O5 . NAG E 3 . ? -15.960 9.430 11.016 1.00 35.41 ? 2003 NAG A O5 1 HETATM 7003 O O6 . NAG E 3 . ? -13.791 8.300 9.539 1.00 38.31 ? 2003 NAG A O6 1 HETATM 7004 O O7 . NAG E 3 . ? -20.713 11.190 13.004 1.00 44.58 ? 2003 NAG A O7 1 HETATM 7005 C C1 . GOL F 4 . ? -6.825 -0.635 31.590 1.00 29.58 ? 3001 GOL A C1 1 HETATM 7006 O O1 . GOL F 4 . ? -7.060 -1.278 32.849 1.00 27.00 ? 3001 GOL A O1 1 HETATM 7007 C C2 . GOL F 4 . ? -5.628 -1.383 30.913 1.00 29.38 ? 3001 GOL A C2 1 HETATM 7008 O O2 . GOL F 4 . ? -4.421 -1.312 31.714 1.00 31.00 ? 3001 GOL A O2 1 HETATM 7009 C C3 . GOL F 4 . ? -5.400 -0.974 29.438 1.00 29.41 ? 3001 GOL A C3 1 HETATM 7010 O O3 . GOL F 4 . ? -4.564 0.132 29.476 1.00 27.84 ? 3001 GOL A O3 1 HETATM 7011 C C1 . GOL G 4 . ? -28.703 -22.346 13.240 1.00 39.96 ? 3002 GOL A C1 1 HETATM 7012 O O1 . GOL G 4 . ? -28.281 -23.391 12.393 1.00 43.50 ? 3002 GOL A O1 1 HETATM 7013 C C2 . GOL G 4 . ? -27.439 -21.640 13.698 1.00 36.87 ? 3002 GOL A C2 1 HETATM 7014 O O2 . GOL G 4 . ? -26.710 -21.164 12.579 1.00 36.99 ? 3002 GOL A O2 1 HETATM 7015 C C3 . GOL G 4 . ? -27.844 -20.455 14.542 1.00 33.55 ? 3002 GOL A C3 1 HETATM 7016 O O3 . GOL G 4 . ? -26.681 -19.684 14.692 1.00 30.12 ? 3002 GOL A O3 1 HETATM 7017 C C1 . GOL H 4 . ? -6.201 -11.667 2.475 1.00 34.06 ? 3003 GOL A C1 1 HETATM 7018 O O1 . GOL H 4 . ? -7.344 -12.424 2.141 1.00 37.17 ? 3003 GOL A O1 1 HETATM 7019 C C2 . GOL H 4 . ? -5.610 -12.290 3.722 1.00 33.73 ? 3003 GOL A C2 1 HETATM 7020 O O2 . GOL H 4 . ? -5.680 -13.685 3.596 1.00 33.43 ? 3003 GOL A O2 1 HETATM 7021 C C3 . GOL H 4 . ? -4.164 -11.868 3.857 1.00 32.78 ? 3003 GOL A C3 1 HETATM 7022 O O3 . GOL H 4 . ? -3.673 -12.269 5.121 1.00 32.91 ? 3003 GOL A O3 1 HETATM 7023 C C1 . GOL I 4 . ? -38.269 12.975 15.814 1.00 37.40 ? 3004 GOL A C1 1 HETATM 7024 O O1 . GOL I 4 . ? -37.210 13.889 16.037 1.00 37.47 ? 3004 GOL A O1 1 HETATM 7025 C C2 . GOL I 4 . ? -37.795 11.705 15.114 1.00 38.82 ? 3004 GOL A C2 1 HETATM 7026 O O2 . GOL I 4 . ? -36.735 11.081 15.810 1.00 39.95 ? 3004 GOL A O2 1 HETATM 7027 C C3 . GOL I 4 . ? -38.955 10.718 15.036 1.00 38.07 ? 3004 GOL A C3 1 HETATM 7028 O O3 . GOL I 4 . ? -39.312 10.208 16.301 1.00 36.16 ? 3004 GOL A O3 1 HETATM 7029 O O . HOH J 5 . ? -19.890 6.084 20.433 1.00 15.72 ? 4002 HOH A O 1 HETATM 7030 O O . HOH J 5 . ? -6.738 -31.954 52.029 1.00 17.56 ? 4003 HOH A O 1 HETATM 7031 O O . HOH J 5 . ? -7.954 -12.389 13.129 1.00 18.86 ? 4004 HOH A O 1 HETATM 7032 O O . HOH J 5 . ? 20.343 -11.097 15.504 1.00 24.27 ? 4005 HOH A O 1 HETATM 7033 O O . HOH J 5 . ? -19.190 0.527 38.705 1.00 15.35 ? 4006 HOH A O 1 HETATM 7034 O O . HOH J 5 . ? -3.925 -6.326 39.088 1.00 14.04 ? 4007 HOH A O 1 HETATM 7035 O O . HOH J 5 . ? -2.456 -30.614 52.700 1.00 19.06 ? 4008 HOH A O 1 HETATM 7036 O O . HOH J 5 . ? -8.058 -17.870 36.594 1.00 16.67 ? 4009 HOH A O 1 HETATM 7037 O O . HOH J 5 . ? -11.496 -3.396 23.613 1.00 12.54 ? 4010 HOH A O 1 HETATM 7038 O O . HOH J 5 . ? -20.104 -6.883 59.229 1.00 21.08 ? 4011 HOH A O 1 HETATM 7039 O O . HOH J 5 . ? -32.033 -11.809 41.338 1.00 16.74 ? 4012 HOH A O 1 HETATM 7040 O O . HOH J 5 . ? -4.448 -9.011 41.188 1.00 12.11 ? 4014 HOH A O 1 HETATM 7041 O O . HOH J 5 . ? 11.446 -28.869 39.052 1.00 18.12 ? 4015 HOH A O 1 HETATM 7042 O O . HOH J 5 . ? -7.347 -12.221 8.731 1.00 16.82 ? 4016 HOH A O 1 HETATM 7043 O O . HOH J 5 . ? -22.298 -13.995 35.951 1.00 15.34 ? 4017 HOH A O 1 HETATM 7044 O O . HOH J 5 . ? -8.095 -2.783 51.728 1.00 15.84 ? 4018 HOH A O 1 HETATM 7045 O O . HOH J 5 . ? -24.795 5.286 34.577 1.00 14.08 ? 4019 HOH A O 1 HETATM 7046 O O . HOH J 5 . ? -17.831 7.299 21.789 1.00 18.56 ? 4020 HOH A O 1 HETATM 7047 O O . HOH J 5 . ? -29.603 -10.360 28.323 1.00 14.92 ? 4021 HOH A O 1 HETATM 7048 O O . HOH J 5 . ? 2.198 -8.313 34.038 1.00 16.20 ? 4022 HOH A O 1 HETATM 7049 O O . HOH J 5 . ? 9.236 -21.591 43.528 1.00 18.51 ? 4023 HOH A O 1 HETATM 7050 O O . HOH J 5 . ? -13.609 0.518 9.959 1.00 15.55 ? 4024 HOH A O 1 HETATM 7051 O O . HOH J 5 . ? -14.683 14.695 22.001 1.00 17.68 ? 4025 HOH A O 1 HETATM 7052 O O . HOH J 5 . ? -7.991 -18.336 26.384 1.00 20.16 ? 4026 HOH A O 1 HETATM 7053 O O . HOH J 5 . ? -4.186 -32.710 48.902 1.00 20.13 ? 4027 HOH A O 1 HETATM 7054 O O . HOH J 5 . ? -11.732 -18.733 25.174 1.00 15.07 ? 4028 HOH A O 1 HETATM 7055 O O . HOH J 5 . ? -7.032 -10.383 11.018 1.00 15.17 ? 4029 HOH A O 1 HETATM 7056 O O . HOH J 5 . ? -12.402 13.580 21.735 1.00 19.55 ? 4030 HOH A O 1 HETATM 7057 O O . HOH J 5 . ? 2.642 -42.983 50.477 1.00 23.58 ? 4031 HOH A O 1 HETATM 7058 O O . HOH J 5 . ? -3.235 7.362 25.392 1.00 20.01 ? 4032 HOH A O 1 HETATM 7059 O O . HOH J 5 . ? -5.495 -13.266 6.999 1.00 18.24 ? 4033 HOH A O 1 HETATM 7060 O O . HOH J 5 . ? -11.576 -10.244 23.063 1.00 15.81 ? 4034 HOH A O 1 HETATM 7061 O O . HOH J 5 . ? 6.569 -21.177 30.168 1.00 15.54 ? 4035 HOH A O 1 HETATM 7062 O O . HOH J 5 . ? 6.524 -12.079 60.853 1.00 18.29 ? 4036 HOH A O 1 HETATM 7063 O O . HOH J 5 . ? -17.399 -13.162 42.497 1.00 18.70 ? 4037 HOH A O 1 HETATM 7064 O O . HOH J 5 . ? 4.660 -25.850 34.112 1.00 16.25 ? 4038 HOH A O 1 HETATM 7065 O O . HOH J 5 . ? -11.456 12.375 19.515 1.00 26.68 ? 4039 HOH A O 1 HETATM 7066 O O . HOH J 5 . ? -6.764 -32.955 49.348 1.00 20.10 ? 4040 HOH A O 1 HETATM 7067 O O . HOH J 5 . ? -0.150 -2.675 41.323 1.00 16.96 ? 4041 HOH A O 1 HETATM 7068 O O . HOH J 5 . ? 15.561 -10.496 18.961 1.00 17.94 ? 4042 HOH A O 1 HETATM 7069 O O . HOH J 5 . ? -4.873 -3.762 39.273 1.00 18.71 ? 4043 HOH A O 1 HETATM 7070 O O . HOH J 5 . ? -6.338 -17.971 30.398 1.00 20.05 ? 4044 HOH A O 1 HETATM 7071 O O . HOH J 5 . ? -6.213 -24.288 33.349 1.00 17.84 ? 4045 HOH A O 1 HETATM 7072 O O . HOH J 5 . ? -7.845 -16.338 24.456 1.00 16.71 ? 4046 HOH A O 1 HETATM 7073 O O . HOH J 5 . ? -4.263 -12.274 43.011 1.00 13.57 ? 4047 HOH A O 1 HETATM 7074 O O . HOH J 5 . ? -23.275 -14.772 38.989 1.00 14.45 ? 4048 HOH A O 1 HETATM 7075 O O . HOH J 5 . ? -8.905 15.478 30.685 1.00 16.85 ? 4049 HOH A O 1 HETATM 7076 O O . HOH J 5 . ? 10.289 -15.350 25.956 1.00 19.51 ? 4050 HOH A O 1 HETATM 7077 O O . HOH J 5 . ? -21.594 -6.149 45.195 1.00 17.25 ? 4051 HOH A O 1 HETATM 7078 O O . HOH J 5 . ? 10.263 -16.067 34.507 1.00 17.05 ? 4052 HOH A O 1 HETATM 7079 O O . HOH J 5 . ? -42.756 -2.401 27.543 1.00 20.46 ? 4053 HOH A O 1 HETATM 7080 O O . HOH J 5 . ? -3.863 1.912 46.392 1.00 23.38 ? 4054 HOH A O 1 HETATM 7081 O O . HOH J 5 . ? -1.683 -13.826 33.247 1.00 18.01 ? 4055 HOH A O 1 HETATM 7082 O O . HOH J 5 . ? -23.174 -15.520 21.414 1.00 16.21 ? 4056 HOH A O 1 HETATM 7083 O O . HOH J 5 . ? -0.012 -20.220 36.755 1.00 14.53 ? 4057 HOH A O 1 HETATM 7084 O O . HOH J 5 . ? -16.363 22.407 18.435 1.00 20.13 ? 4058 HOH A O 1 HETATM 7085 O O . HOH J 5 . ? -18.447 -6.611 61.449 1.00 14.31 ? 4059 HOH A O 1 HETATM 7086 O O . HOH J 5 . ? 12.633 -27.565 52.671 1.00 21.49 ? 4060 HOH A O 1 HETATM 7087 O O . HOH J 5 . ? -3.106 -31.722 46.398 1.00 24.78 ? 4061 HOH A O 1 HETATM 7088 O O . HOH J 5 . ? -12.912 -20.821 32.666 1.00 15.70 ? 4062 HOH A O 1 HETATM 7089 O O . HOH J 5 . ? 2.441 -2.794 41.283 1.00 17.80 ? 4063 HOH A O 1 HETATM 7090 O O . HOH J 5 . ? -10.196 0.384 45.620 1.00 17.69 ? 4065 HOH A O 1 HETATM 7091 O O . HOH J 5 . ? -4.476 2.156 43.519 1.00 20.41 ? 4066 HOH A O 1 HETATM 7092 O O . HOH J 5 . ? -15.024 2.127 7.916 1.00 22.91 ? 4067 HOH A O 1 HETATM 7093 O O . HOH J 5 . ? -19.757 -19.852 30.152 1.00 21.77 ? 4068 HOH A O 1 HETATM 7094 O O . HOH J 5 . ? 5.950 -10.311 51.994 1.00 20.14 ? 4069 HOH A O 1 HETATM 7095 O O . HOH J 5 . ? -35.378 -2.766 38.523 1.00 19.44 ? 4070 HOH A O 1 HETATM 7096 O O . HOH J 5 . ? 6.080 -12.294 50.107 1.00 17.52 ? 4072 HOH A O 1 HETATM 7097 O O . HOH J 5 . ? -20.378 -16.467 5.838 1.00 26.24 ? 4073 HOH A O 1 HETATM 7098 O O . HOH J 5 . ? -25.955 -17.729 28.013 1.00 20.10 ? 4074 HOH A O 1 HETATM 7099 O O . HOH J 5 . ? 0.605 5.716 1.940 1.00 26.78 ? 4075 HOH A O 1 HETATM 7100 O O . HOH J 5 . ? -11.178 3.746 9.869 1.00 24.94 ? 4076 HOH A O 1 HETATM 7101 O O . HOH J 5 . ? -10.860 -18.677 30.063 1.00 19.84 ? 4077 HOH A O 1 HETATM 7102 O O . HOH J 5 . ? 0.535 -31.493 53.082 1.00 19.58 ? 4078 HOH A O 1 HETATM 7103 O O . HOH J 5 . ? 5.292 -13.587 20.647 1.00 19.55 ? 4079 HOH A O 1 HETATM 7104 O O . HOH J 5 . ? -21.910 -13.601 57.212 1.00 22.17 ? 4081 HOH A O 1 HETATM 7105 O O . HOH J 5 . ? 15.508 -0.229 19.283 1.00 20.07 ? 4082 HOH A O 1 HETATM 7106 O O . HOH J 5 . ? -21.246 2.105 38.472 1.00 26.22 ? 4083 HOH A O 1 HETATM 7107 O O . HOH J 5 . ? -11.057 -19.587 34.435 1.00 15.34 ? 4084 HOH A O 1 HETATM 7108 O O . HOH J 5 . ? -40.596 0.109 27.985 1.00 18.35 ? 4085 HOH A O 1 HETATM 7109 O O . HOH J 5 . ? -20.304 -21.035 38.355 1.00 19.76 ? 4086 HOH A O 1 HETATM 7110 O O . HOH J 5 . ? -25.860 -14.801 21.163 1.00 20.64 ? 4087 HOH A O 1 HETATM 7111 O O . HOH J 5 . ? -5.007 -29.786 51.949 1.00 23.27 ? 4088 HOH A O 1 HETATM 7112 O O . HOH J 5 . ? 7.365 -24.542 34.015 1.00 24.27 ? 4089 HOH A O 1 HETATM 7113 O O . HOH J 5 . ? -12.239 -25.825 41.810 1.00 24.09 ? 4090 HOH A O 1 HETATM 7114 O O . HOH J 5 . ? 11.882 -14.884 57.491 1.00 19.58 ? 4091 HOH A O 1 HETATM 7115 O O . HOH J 5 . ? -21.830 -26.707 21.844 1.00 23.58 ? 4092 HOH A O 1 HETATM 7116 O O . HOH J 5 . ? 12.207 -18.967 49.098 1.00 21.25 ? 4093 HOH A O 1 HETATM 7117 O O . HOH J 5 . ? 19.762 -14.027 29.721 1.00 17.89 ? 4094 HOH A O 1 HETATM 7118 O O . HOH J 5 . ? -12.364 1.978 11.470 1.00 22.15 ? 4095 HOH A O 1 HETATM 7119 O O . HOH J 5 . ? -21.105 -2.358 46.939 1.00 22.79 ? 4096 HOH A O 1 HETATM 7120 O O . HOH J 5 . ? 14.522 -19.745 56.742 1.00 23.20 ? 4097 HOH A O 1 HETATM 7121 O O . HOH J 5 . ? 13.793 -17.465 51.029 1.00 18.89 ? 4098 HOH A O 1 HETATM 7122 O O . HOH J 5 . ? -17.023 -0.216 37.241 1.00 16.68 ? 4099 HOH A O 1 HETATM 7123 O O . HOH J 5 . ? -7.674 -14.029 10.778 1.00 14.95 ? 4100 HOH A O 1 HETATM 7124 O O . HOH J 5 . ? -5.513 -25.906 31.141 1.00 25.02 ? 4101 HOH A O 1 HETATM 7125 O O . HOH J 5 . ? 6.131 -14.275 34.884 1.00 16.40 ? 4102 HOH A O 1 HETATM 7126 O O . HOH J 5 . ? 9.895 -27.881 47.501 1.00 18.58 ? 4103 HOH A O 1 HETATM 7127 O O . HOH J 5 . ? -2.982 -15.758 21.728 1.00 19.00 ? 4104 HOH A O 1 HETATM 7128 O O . HOH J 5 . ? -22.713 -3.755 45.340 1.00 23.45 ? 4105 HOH A O 1 HETATM 7129 O O . HOH J 5 . ? 2.555 -6.014 64.558 1.00 19.49 ? 4106 HOH A O 1 HETATM 7130 O O . HOH J 5 . ? -5.071 1.912 27.275 1.00 15.88 ? 4109 HOH A O 1 HETATM 7131 O O . HOH J 5 . ? -2.951 -6.097 75.876 1.00 20.74 ? 4110 HOH A O 1 HETATM 7132 O O . HOH J 5 . ? -7.265 -11.312 22.232 1.00 19.40 ? 4111 HOH A O 1 HETATM 7133 O O . HOH J 5 . ? -32.442 -23.722 19.513 1.00 26.90 ? 4112 HOH A O 1 HETATM 7134 O O . HOH J 5 . ? -7.936 -27.709 51.847 1.00 19.22 ? 4113 HOH A O 1 HETATM 7135 O O . HOH J 5 . ? -25.235 -3.854 46.309 1.00 29.88 ? 4114 HOH A O 1 HETATM 7136 O O . HOH J 5 . ? -3.696 -24.665 58.666 1.00 20.32 ? 4115 HOH A O 1 HETATM 7137 O O . HOH J 5 . ? -27.602 -4.548 43.234 1.00 19.68 ? 4116 HOH A O 1 HETATM 7138 O O . HOH J 5 . ? 3.020 -32.231 37.743 1.00 23.68 ? 4117 HOH A O 1 HETATM 7139 O O . HOH J 5 . ? -3.754 -39.358 51.683 1.00 18.56 ? 4118 HOH A O 1 HETATM 7140 O O . HOH J 5 . ? 9.377 -11.783 11.426 1.00 15.21 ? 4119 HOH A O 1 HETATM 7141 O O . HOH J 5 . ? 16.047 -15.364 45.709 1.00 24.67 ? 4120 HOH A O 1 HETATM 7142 O O . HOH J 5 . ? 7.735 -14.534 50.027 1.00 13.90 ? 4121 HOH A O 1 HETATM 7143 O O . HOH J 5 . ? 1.329 -4.187 54.042 1.00 24.44 ? 4123 HOH A O 1 HETATM 7144 O O . HOH J 5 . ? -4.960 8.781 37.733 1.00 33.18 ? 4124 HOH A O 1 HETATM 7145 O O . HOH J 5 . ? 13.141 -10.506 19.911 1.00 20.33 ? 4125 HOH A O 1 HETATM 7146 O O . HOH J 5 . ? 1.763 -32.650 33.530 1.00 22.23 ? 4126 HOH A O 1 HETATM 7147 O O . HOH J 5 . ? -21.968 -15.601 7.760 1.00 20.63 ? 4127 HOH A O 1 HETATM 7148 O O . HOH J 5 . ? 2.681 -7.734 51.647 1.00 20.44 ? 4128 HOH A O 1 HETATM 7149 O O . HOH J 5 . ? 7.058 -21.719 33.165 1.00 24.63 ? 4129 HOH A O 1 HETATM 7150 O O . HOH J 5 . ? -6.460 -33.354 59.090 1.00 18.90 ? 4130 HOH A O 1 HETATM 7151 O O . HOH J 5 . ? 10.542 -13.702 23.866 1.00 21.96 ? 4131 HOH A O 1 HETATM 7152 O O . HOH J 5 . ? 18.874 0.627 24.654 1.00 20.15 ? 4132 HOH A O 1 HETATM 7153 O O . HOH J 5 . ? -9.930 -21.770 26.567 1.00 27.99 ? 4133 HOH A O 1 HETATM 7154 O O . HOH J 5 . ? -25.511 18.279 30.884 1.00 22.28 ? 4134 HOH A O 1 HETATM 7155 O O . HOH J 5 . ? -2.497 -27.048 56.525 1.00 19.56 ? 4135 HOH A O 1 HETATM 7156 O O . HOH J 5 . ? -8.757 -18.440 31.622 1.00 22.85 ? 4136 HOH A O 1 HETATM 7157 O O . HOH J 5 . ? -24.866 20.866 39.200 1.00 24.34 ? 4137 HOH A O 1 HETATM 7158 O O . HOH J 5 . ? 5.964 5.221 11.354 1.00 26.03 ? 4139 HOH A O 1 HETATM 7159 O O . HOH J 5 . ? -23.282 17.081 31.638 1.00 29.96 ? 4141 HOH A O 1 HETATM 7160 O O . HOH J 5 . ? -13.612 -18.534 40.081 1.00 16.40 ? 4143 HOH A O 1 HETATM 7161 O O . HOH J 5 . ? -31.789 -10.147 43.807 1.00 22.44 ? 4144 HOH A O 1 HETATM 7162 O O . HOH J 5 . ? -15.636 -5.631 2.911 1.00 27.26 ? 4145 HOH A O 1 HETATM 7163 O O . HOH J 5 . ? -13.795 -24.810 39.869 1.00 25.60 ? 4146 HOH A O 1 HETATM 7164 O O . HOH J 5 . ? 4.528 -20.715 15.445 1.00 23.36 ? 4147 HOH A O 1 HETATM 7165 O O . HOH J 5 . ? -20.531 3.073 12.973 1.00 25.69 ? 4149 HOH A O 1 HETATM 7166 O O . HOH J 5 . ? -38.601 12.348 19.592 1.00 22.66 ? 4150 HOH A O 1 HETATM 7167 O O . HOH J 5 . ? -24.574 3.625 36.656 1.00 33.51 ? 4151 HOH A O 1 HETATM 7168 O O . HOH J 5 . ? -25.898 -20.913 17.283 1.00 24.04 ? 4152 HOH A O 1 HETATM 7169 O O . HOH J 5 . ? 6.086 -4.521 48.925 1.00 29.65 ? 4153 HOH A O 1 HETATM 7170 O O . HOH J 5 . ? -2.262 0.093 29.517 1.00 26.90 ? 4154 HOH A O 1 HETATM 7171 O O . HOH J 5 . ? -3.564 4.132 31.463 1.00 20.38 ? 4155 HOH A O 1 HETATM 7172 O O . HOH J 5 . ? -30.136 -7.450 20.121 1.00 28.50 ? 4156 HOH A O 1 HETATM 7173 O O . HOH J 5 . ? -14.553 -20.136 57.999 1.00 18.52 ? 4157 HOH A O 1 HETATM 7174 O O . HOH J 5 . ? -0.189 -20.560 15.707 1.00 21.04 ? 4158 HOH A O 1 HETATM 7175 O O . HOH J 5 . ? -15.089 -25.559 57.042 1.00 24.29 ? 4159 HOH A O 1 HETATM 7176 O O . HOH J 5 . ? -14.463 6.986 12.242 1.00 25.54 ? 4160 HOH A O 1 HETATM 7177 O O . HOH J 5 . ? -0.710 -13.242 43.051 1.00 21.44 ? 4161 HOH A O 1 HETATM 7178 O O . HOH J 5 . ? -20.722 0.810 10.925 1.00 22.08 ? 4162 HOH A O 1 HETATM 7179 O O . HOH J 5 . ? -8.398 -31.472 47.413 1.00 26.96 ? 4163 HOH A O 1 HETATM 7180 O O . HOH J 5 . ? 7.370 -15.645 47.459 1.00 20.36 ? 4164 HOH A O 1 HETATM 7181 O O . HOH J 5 . ? -12.147 15.372 24.440 1.00 24.51 ? 4165 HOH A O 1 HETATM 7182 O O . HOH J 5 . ? 10.892 -12.144 19.113 1.00 21.35 ? 4166 HOH A O 1 HETATM 7183 O O . HOH J 5 . ? 6.834 -8.020 50.500 1.00 18.40 ? 4167 HOH A O 1 HETATM 7184 O O . HOH J 5 . ? 11.732 -12.565 55.940 1.00 26.13 ? 4168 HOH A O 1 HETATM 7185 O O . HOH J 5 . ? 22.948 -20.370 29.460 1.00 23.97 ? 4169 HOH A O 1 HETATM 7186 O O . HOH J 5 . ? -6.899 16.863 29.924 1.00 25.63 ? 4171 HOH A O 1 HETATM 7187 O O . HOH J 5 . ? -14.654 7.007 42.161 1.00 25.57 ? 4172 HOH A O 1 HETATM 7188 O O . HOH J 5 . ? -15.000 12.385 41.399 1.00 32.12 ? 4173 HOH A O 1 HETATM 7189 O O . HOH J 5 . ? -11.112 22.061 29.779 1.00 25.97 ? 4174 HOH A O 1 HETATM 7190 O O . HOH J 5 . ? -18.086 -5.620 55.957 1.00 25.21 ? 4175 HOH A O 1 HETATM 7191 O O . HOH J 5 . ? -1.153 -29.109 35.806 1.00 25.48 ? 4176 HOH A O 1 HETATM 7192 O O . HOH J 5 . ? -23.985 -9.176 60.387 1.00 24.98 ? 4177 HOH A O 1 HETATM 7193 O O . HOH J 5 . ? -18.081 -22.936 8.641 1.00 32.10 ? 4178 HOH A O 1 HETATM 7194 O O . HOH J 5 . ? -22.149 -0.173 40.324 1.00 28.94 ? 4179 HOH A O 1 HETATM 7195 O O . HOH J 5 . ? -6.998 -32.358 44.878 1.00 22.19 ? 4180 HOH A O 1 HETATM 7196 O O . HOH J 5 . ? 10.452 -31.312 39.735 1.00 24.67 ? 4181 HOH A O 1 HETATM 7197 O O . HOH J 5 . ? 22.218 -8.360 34.538 1.00 19.71 ? 4182 HOH A O 1 HETATM 7198 O O . HOH J 5 . ? -20.479 -28.478 20.484 1.00 33.12 ? 4183 HOH A O 1 HETATM 7199 O O . HOH J 5 . ? 10.655 -41.095 59.325 1.00 35.06 ? 4184 HOH A O 1 HETATM 7200 O O . HOH J 5 . ? -10.179 -19.419 11.389 1.00 26.13 ? 4185 HOH A O 1 HETATM 7201 O O . HOH J 5 . ? -22.542 5.416 33.313 1.00 20.32 ? 4186 HOH A O 1 HETATM 7202 O O . HOH J 5 . ? -18.251 19.769 25.109 1.00 21.65 ? 4188 HOH A O 1 HETATM 7203 O O . HOH J 5 . ? -16.100 -36.098 49.470 1.00 27.43 ? 4189 HOH A O 1 HETATM 7204 O O . HOH J 5 . ? -15.955 -21.812 59.356 1.00 28.73 ? 4194 HOH A O 1 HETATM 7205 O O . HOH J 5 . ? -5.897 1.593 52.621 1.00 34.95 ? 4195 HOH A O 1 HETATM 7206 O O . HOH J 5 . ? -21.466 -5.040 58.182 1.00 33.76 ? 4196 HOH A O 1 HETATM 7207 O O . HOH J 5 . ? 10.820 6.574 30.890 1.00 24.32 ? 4197 HOH A O 1 HETATM 7208 O O . HOH J 5 . ? 0.049 -20.917 25.223 1.00 22.00 ? 4198 HOH A O 1 HETATM 7209 O O . HOH J 5 . ? -49.784 6.754 28.770 1.00 29.65 ? 4199 HOH A O 1 HETATM 7210 O O . HOH J 5 . ? -2.587 -26.532 29.479 1.00 22.41 ? 4200 HOH A O 1 HETATM 7211 O O . HOH J 5 . ? 21.672 -21.361 35.631 1.00 27.16 ? 4201 HOH A O 1 HETATM 7212 O O . HOH J 5 . ? -19.078 -19.103 61.866 1.00 23.08 ? 4202 HOH A O 1 HETATM 7213 O O . HOH J 5 . ? -24.687 -6.773 53.104 1.00 23.53 ? 4203 HOH A O 1 HETATM 7214 O O . HOH J 5 . ? -2.479 5.436 0.909 1.00 25.88 ? 4204 HOH A O 1 HETATM 7215 O O . HOH J 5 . ? -7.241 -35.502 48.877 1.00 32.80 ? 4205 HOH A O 1 HETATM 7216 O O . HOH J 5 . ? -8.306 -26.291 11.678 1.00 27.23 ? 4206 HOH A O 1 HETATM 7217 O O . HOH J 5 . ? -26.349 -21.404 24.968 1.00 26.96 ? 4207 HOH A O 1 HETATM 7218 O O . HOH J 5 . ? 7.164 -27.094 59.619 1.00 27.13 ? 4208 HOH A O 1 HETATM 7219 O O . HOH J 5 . ? 4.800 -15.458 71.706 1.00 21.33 ? 4209 HOH A O 1 HETATM 7220 O O . HOH J 5 . ? 4.222 -11.915 36.210 1.00 19.03 ? 4210 HOH A O 1 HETATM 7221 O O . HOH J 5 . ? -32.112 16.125 18.985 1.00 25.72 ? 4212 HOH A O 1 HETATM 7222 O O . HOH J 5 . ? -33.941 -10.898 45.073 1.00 25.34 ? 4213 HOH A O 1 HETATM 7223 O O . HOH J 5 . ? 6.902 -12.553 6.058 1.00 19.88 ? 4214 HOH A O 1 HETATM 7224 O O . HOH J 5 . ? -6.040 -40.676 49.425 1.00 26.24 ? 4215 HOH A O 1 HETATM 7225 O O . HOH J 5 . ? -20.588 -23.308 10.884 1.00 26.86 ? 4216 HOH A O 1 HETATM 7226 O O . HOH J 5 . ? -44.749 6.514 33.969 1.00 25.98 ? 4217 HOH A O 1 HETATM 7227 O O . HOH J 5 . ? 12.463 -9.614 34.894 1.00 24.92 ? 4218 HOH A O 1 HETATM 7228 O O . HOH J 5 . ? 4.160 -6.462 1.370 1.00 27.50 ? 4219 HOH A O 1 HETATM 7229 O O . HOH J 5 . ? 0.845 -9.846 12.264 1.00 26.34 ? 4220 HOH A O 1 HETATM 7230 O O . HOH J 5 . ? -9.368 -26.556 32.515 1.00 24.10 ? 4221 HOH A O 1 HETATM 7231 O O . HOH J 5 . ? -9.464 2.068 58.780 1.00 28.86 ? 4222 HOH A O 1 HETATM 7232 O O . HOH J 5 . ? -6.222 -28.614 38.340 1.00 30.72 ? 4223 HOH A O 1 HETATM 7233 O O . HOH J 5 . ? 0.301 -0.871 51.427 1.00 31.23 ? 4224 HOH A O 1 HETATM 7234 O O . HOH J 5 . ? -8.943 -31.201 60.226 1.00 27.31 ? 4225 HOH A O 1 HETATM 7235 O O . HOH J 5 . ? 21.159 1.894 25.388 1.00 27.35 ? 4226 HOH A O 1 HETATM 7236 O O . HOH J 5 . ? -22.731 -21.987 9.646 1.00 31.01 ? 4227 HOH A O 1 HETATM 7237 O O . HOH J 5 . ? -8.601 1.851 53.270 1.00 30.60 ? 4228 HOH A O 1 HETATM 7238 O O . HOH J 5 . ? -1.489 -0.406 49.075 1.00 21.57 ? 4229 HOH A O 1 HETATM 7239 O O . HOH J 5 . ? -0.782 -17.351 8.313 1.00 22.84 ? 4230 HOH A O 1 HETATM 7240 O O . HOH J 5 . ? 4.158 -4.115 73.992 1.00 27.77 ? 4231 HOH A O 1 HETATM 7241 O O . HOH J 5 . ? -28.197 24.925 27.357 1.00 34.92 ? 4232 HOH A O 1 HETATM 7242 O O . HOH J 5 . ? -11.355 -4.629 38.088 1.00 18.49 ? 4233 HOH A O 1 HETATM 7243 O O . HOH J 5 . ? -1.461 2.954 30.757 1.00 35.93 ? 4234 HOH A O 1 HETATM 7244 O O . HOH J 5 . ? -16.394 -27.277 19.302 1.00 27.36 ? 4235 HOH A O 1 HETATM 7245 O O . HOH J 5 . ? -20.573 20.946 25.720 1.00 26.33 ? 4236 HOH A O 1 HETATM 7246 O O . HOH J 5 . ? -37.360 -20.198 37.378 1.00 26.64 ? 4237 HOH A O 1 HETATM 7247 O O . HOH J 5 . ? 0.447 1.447 31.877 1.00 28.06 ? 4238 HOH A O 1 HETATM 7248 O O . HOH J 5 . ? -8.008 -24.281 24.289 1.00 30.18 ? 4240 HOH A O 1 HETATM 7249 O O . HOH J 5 . ? -10.155 -19.302 27.515 1.00 30.79 ? 4241 HOH A O 1 HETATM 7250 O O . HOH J 5 . ? 11.653 -11.715 8.382 1.00 28.29 ? 4242 HOH A O 1 HETATM 7251 O O . HOH J 5 . ? -24.035 -28.017 23.585 1.00 33.06 ? 4243 HOH A O 1 HETATM 7252 O O . HOH J 5 . ? 8.186 -11.162 7.616 1.00 28.31 ? 4244 HOH A O 1 HETATM 7253 O O . HOH J 5 . ? 12.692 -32.737 40.066 1.00 26.99 ? 4245 HOH A O 1 HETATM 7254 O O . HOH J 5 . ? -39.183 20.570 19.013 1.00 30.88 ? 4246 HOH A O 1 HETATM 7255 O O . HOH J 5 . ? -23.758 6.467 13.696 1.00 27.35 ? 4247 HOH A O 1 HETATM 7256 O O . HOH J 5 . ? -36.163 -9.522 25.187 1.00 27.97 ? 4248 HOH A O 1 HETATM 7257 O O . HOH J 5 . ? -8.802 -8.689 67.332 1.00 26.32 ? 4249 HOH A O 1 HETATM 7258 O O . HOH J 5 . ? -26.393 16.729 20.043 1.00 45.09 ? 4250 HOH A O 1 HETATM 7259 O O . HOH J 5 . ? 4.687 -6.421 50.386 1.00 22.06 ? 4251 HOH A O 1 HETATM 7260 O O . HOH J 5 . ? 25.454 1.069 24.259 1.00 39.45 ? 4253 HOH A O 1 HETATM 7261 O O . HOH J 5 . ? -26.351 -1.384 16.064 1.00 21.28 ? 4254 HOH A O 1 HETATM 7262 O O . HOH J 5 . ? -10.026 -0.547 54.035 1.00 25.72 ? 4255 HOH A O 1 HETATM 7263 O O . HOH J 5 . ? -44.891 -3.398 27.327 1.00 40.37 ? 4256 HOH A O 1 HETATM 7264 O O . HOH J 5 . ? -9.317 5.973 17.276 1.00 26.13 ? 4257 HOH A O 1 HETATM 7265 O O . HOH J 5 . ? 23.845 1.787 19.666 1.00 32.88 ? 4258 HOH A O 1 HETATM 7266 O O . HOH J 5 . ? -4.580 5.394 34.830 1.00 26.96 ? 4259 HOH A O 1 HETATM 7267 O O . HOH J 5 . ? -18.228 -27.279 45.883 1.00 27.78 ? 4260 HOH A O 1 HETATM 7268 O O . HOH J 5 . ? -19.600 -1.553 42.252 1.00 26.41 ? 4261 HOH A O 1 HETATM 7269 O O . HOH J 5 . ? 13.070 -21.489 49.503 1.00 24.42 ? 4262 HOH A O 1 HETATM 7270 O O . HOH J 5 . ? 26.225 -9.391 31.306 1.00 33.35 ? 4263 HOH A O 1 HETATM 7271 O O . HOH J 5 . ? -29.769 -20.346 38.100 1.00 37.79 ? 4264 HOH A O 1 HETATM 7272 O O . HOH J 5 . ? -6.158 9.241 34.592 1.00 32.81 ? 4265 HOH A O 1 HETATM 7273 O O . HOH J 5 . ? -2.725 -29.218 28.729 1.00 29.48 ? 4266 HOH A O 1 HETATM 7274 O O . HOH J 5 . ? -36.447 0.697 18.618 1.00 32.74 ? 4267 HOH A O 1 HETATM 7275 O O . HOH J 5 . ? -24.981 -4.426 10.287 1.00 28.02 ? 4268 HOH A O 1 HETATM 7276 O O . HOH J 5 . ? -24.339 -15.570 5.607 1.00 34.76 ? 4269 HOH A O 1 HETATM 7277 O O . HOH J 5 . ? -1.478 -47.765 50.390 1.00 27.45 ? 4270 HOH A O 1 HETATM 7278 O O . HOH J 5 . ? -20.970 -22.341 29.872 1.00 52.68 ? 4271 HOH A O 1 HETATM 7279 O O . HOH J 5 . ? 25.082 -18.966 30.569 1.00 32.61 ? 4272 HOH A O 1 HETATM 7280 O O . HOH J 5 . ? 25.069 -14.480 24.501 1.00 32.25 ? 4273 HOH A O 1 HETATM 7281 O O . HOH J 5 . ? -24.620 -19.909 33.925 1.00 21.93 ? 4274 HOH A O 1 HETATM 7282 O O . HOH J 5 . ? -32.685 -3.496 40.431 1.00 22.91 ? 4275 HOH A O 1 HETATM 7283 O O . HOH J 5 . ? -43.120 -0.964 30.407 1.00 24.88 ? 4276 HOH A O 1 HETATM 7284 O O . HOH J 5 . ? 23.758 -9.312 31.938 1.00 22.23 ? 4277 HOH A O 1 HETATM 7285 O O . HOH J 5 . ? 8.051 -39.078 54.820 1.00 40.56 ? 4278 HOH A O 1 HETATM 7286 O O . HOH J 5 . ? -11.685 -14.502 65.925 1.00 34.37 ? 4279 HOH A O 1 HETATM 7287 O O . HOH J 5 . ? -2.109 -22.424 16.824 1.00 34.11 ? 4280 HOH A O 1 HETATM 7288 O O . HOH J 5 . ? -9.111 18.275 25.099 1.00 26.35 ? 4281 HOH A O 1 HETATM 7289 O O . HOH J 5 . ? -27.248 -9.033 14.314 1.00 26.91 ? 4282 HOH A O 1 HETATM 7290 O O . HOH J 5 . ? -42.363 8.456 33.723 1.00 37.17 ? 4284 HOH A O 1 HETATM 7291 O O . HOH J 5 . ? -27.719 -18.494 29.793 1.00 30.53 ? 4285 HOH A O 1 HETATM 7292 O O . HOH J 5 . ? -27.894 -17.311 52.392 1.00 32.40 ? 4286 HOH A O 1 HETATM 7293 O O . HOH J 5 . ? 13.005 5.127 31.383 1.00 28.64 ? 4287 HOH A O 1 HETATM 7294 O O . HOH J 5 . ? 11.777 -13.588 21.373 1.00 25.17 ? 4288 HOH A O 1 HETATM 7295 O O . HOH J 5 . ? 25.959 -15.843 27.435 1.00 30.59 ? 4289 HOH A O 1 HETATM 7296 O O . HOH J 5 . ? -6.836 -3.772 33.024 1.00 30.38 ? 4290 HOH A O 1 HETATM 7297 O O . HOH J 5 . ? 1.303 -18.673 7.419 1.00 37.20 ? 4291 HOH A O 1 HETATM 7298 O O . HOH J 5 . ? -17.494 -17.141 66.290 1.00 39.60 ? 4292 HOH A O 1 HETATM 7299 O O . HOH J 5 . ? 23.876 -31.169 37.687 1.00 29.35 ? 4293 HOH A O 1 HETATM 7300 O O . HOH J 5 . ? -13.362 -16.641 6.487 1.00 32.80 ? 4294 HOH A O 1 HETATM 7301 O O . HOH J 5 . ? 7.441 -8.136 63.034 1.00 33.65 ? 4295 HOH A O 1 HETATM 7302 O O . HOH J 5 . ? 15.623 -19.507 47.043 1.00 43.86 ? 4296 HOH A O 1 HETATM 7303 O O . HOH J 5 . ? -41.739 0.251 35.021 1.00 39.76 ? 4297 HOH A O 1 HETATM 7304 O O . HOH J 5 . ? 16.411 -14.198 13.807 1.00 28.13 ? 4298 HOH A O 1 HETATM 7305 O O . HOH J 5 . ? -32.468 22.130 24.959 1.00 35.24 ? 4299 HOH A O 1 HETATM 7306 O O . HOH J 5 . ? 8.999 -6.947 51.838 1.00 27.75 ? 4300 HOH A O 1 HETATM 7307 O O . HOH J 5 . ? -9.898 7.925 20.911 1.00 28.85 ? 4301 HOH A O 1 HETATM 7308 O O . HOH J 5 . ? -18.849 -4.349 62.810 1.00 31.22 ? 4302 HOH A O 1 HETATM 7309 O O . HOH J 5 . ? 7.699 -37.248 47.777 1.00 37.94 ? 4303 HOH A O 1 HETATM 7310 O O . HOH J 5 . ? 3.192 7.877 29.441 1.00 27.15 ? 4304 HOH A O 1 HETATM 7311 O O . HOH J 5 . ? -15.818 -8.327 2.767 1.00 30.75 ? 4305 HOH A O 1 HETATM 7312 O O . HOH J 5 . ? 20.375 -7.368 36.221 1.00 25.88 ? 4306 HOH A O 1 HETATM 7313 O O . HOH J 5 . ? -15.655 -37.731 47.428 1.00 36.33 ? 4307 HOH A O 1 HETATM 7314 O O . HOH J 5 . ? 6.708 -33.486 44.269 1.00 27.88 ? 4308 HOH A O 1 HETATM 7315 O O . HOH J 5 . ? -41.466 -5.451 21.777 1.00 41.56 ? 4309 HOH A O 1 HETATM 7316 O O . HOH J 5 . ? 9.848 -4.639 18.335 1.00 22.24 ? 4310 HOH A O 1 HETATM 7317 O O . HOH J 5 . ? 10.218 11.859 25.452 1.00 34.89 ? 4311 HOH A O 1 HETATM 7318 O O . HOH J 5 . ? -14.929 -27.243 58.863 1.00 38.52 ? 4312 HOH A O 1 HETATM 7319 O O . HOH J 5 . ? -20.672 3.947 36.870 1.00 36.69 ? 4313 HOH A O 1 HETATM 7320 O O . HOH J 5 . ? 14.434 -28.595 26.048 1.00 33.44 ? 4314 HOH A O 1 HETATM 7321 O O . HOH J 5 . ? -3.418 -23.660 62.418 1.00 25.88 ? 4315 HOH A O 1 HETATM 7322 O O . HOH J 5 . ? 7.119 -7.440 68.817 1.00 41.17 ? 4316 HOH A O 1 HETATM 7323 O O . HOH J 5 . ? -4.352 7.680 33.625 1.00 35.18 ? 4317 HOH A O 1 HETATM 7324 O O . HOH J 5 . ? -26.062 -1.232 41.659 1.00 30.03 ? 4318 HOH A O 1 HETATM 7325 O O . HOH J 5 . ? 7.286 -9.678 -0.194 1.00 38.02 ? 4319 HOH A O 1 HETATM 7326 O O . HOH J 5 . ? -24.390 24.404 35.337 1.00 33.79 ? 4320 HOH A O 1 HETATM 7327 O O . HOH J 5 . ? 6.489 -13.949 8.023 1.00 31.56 ? 4321 HOH A O 1 HETATM 7328 O O . HOH J 5 . ? 0.985 -41.913 63.226 1.00 35.14 ? 4322 HOH A O 1 HETATM 7329 O O . HOH J 5 . ? -28.655 -22.973 24.219 1.00 29.39 ? 4323 HOH A O 1 HETATM 7330 O O . HOH J 5 . ? -40.395 8.916 35.479 1.00 39.94 ? 4324 HOH A O 1 HETATM 7331 O O . HOH J 5 . ? -22.237 -22.860 51.314 1.00 41.67 ? 4325 HOH A O 1 HETATM 7332 O O . HOH J 5 . ? -18.906 -28.585 22.464 1.00 35.43 ? 4327 HOH A O 1 HETATM 7333 O O . HOH J 5 . ? 19.121 -15.496 17.684 1.00 23.08 ? 4329 HOH A O 1 HETATM 7334 O O . HOH J 5 . ? 6.388 1.914 35.882 1.00 31.75 ? 4330 HOH A O 1 HETATM 7335 O O . HOH J 5 . ? -18.063 -26.324 28.045 1.00 33.30 ? 4331 HOH A O 1 HETATM 7336 O O . HOH J 5 . ? -26.828 -10.029 57.360 1.00 39.67 ? 4332 HOH A O 1 HETATM 7337 O O . HOH J 5 . ? -12.954 2.305 47.255 1.00 34.03 ? 4333 HOH A O 1 HETATM 7338 O O . HOH J 5 . ? 7.051 -11.713 69.664 1.00 33.97 ? 4334 HOH A O 1 HETATM 7339 O O . HOH J 5 . ? 10.232 0.591 4.306 1.00 30.91 ? 4337 HOH A O 1 HETATM 7340 O O . HOH J 5 . ? -4.588 2.140 60.603 1.00 25.40 ? 4338 HOH A O 1 HETATM 7341 O O . HOH J 5 . ? 25.898 -10.282 26.752 1.00 35.52 ? 4339 HOH A O 1 HETATM 7342 O O . HOH J 5 . ? 8.787 -7.870 70.661 1.00 38.24 ? 4340 HOH A O 1 HETATM 7343 O O . HOH J 5 . ? 2.849 -17.457 43.253 1.00 32.04 ? 4341 HOH A O 1 HETATM 7344 O O . HOH J 5 . ? 9.020 -5.486 -0.991 1.00 34.60 ? 4342 HOH A O 1 HETATM 7345 O O . HOH J 5 . ? 11.365 -38.787 58.032 1.00 51.55 ? 4343 HOH A O 1 HETATM 7346 O O . HOH J 5 . ? -40.991 -11.016 27.706 1.00 33.80 ? 4345 HOH A O 1 HETATM 7347 O O . HOH J 5 . ? 1.619 8.520 11.615 1.00 32.30 ? 4346 HOH A O 1 HETATM 7348 O O . HOH J 5 . ? -12.195 -1.723 66.865 1.00 30.86 ? 4347 HOH A O 1 HETATM 7349 O O . HOH J 5 . ? 0.548 2.802 34.507 1.00 36.38 ? 4348 HOH A O 1 HETATM 7350 O O . HOH J 5 . ? 0.237 -27.759 71.265 1.00 42.66 ? 4349 HOH A O 1 HETATM 7351 O O . HOH J 5 . ? 1.636 -10.474 -0.128 1.00 33.70 ? 4350 HOH A O 1 HETATM 7352 O O . HOH J 5 . ? 9.248 -8.459 65.649 1.00 41.28 ? 4352 HOH A O 1 HETATM 7353 O O . HOH J 5 . ? 17.705 -30.207 36.768 1.00 28.62 ? 4353 HOH A O 1 HETATM 7354 O O . HOH J 5 . ? -17.091 -6.023 69.414 1.00 33.86 ? 4354 HOH A O 1 HETATM 7355 O O . HOH J 5 . ? -13.574 4.980 8.898 1.00 39.43 ? 4355 HOH A O 1 HETATM 7356 O O . HOH J 5 . ? 0.007 -35.154 62.143 1.00 31.89 ? 4356 HOH A O 1 HETATM 7357 O O . HOH J 5 . ? 14.914 -27.498 51.373 1.00 33.77 ? 4357 HOH A O 1 HETATM 7358 O O . HOH J 5 . ? -2.598 -4.801 -0.069 1.00 36.03 ? 4358 HOH A O 1 HETATM 7359 O O . HOH J 5 . ? -14.036 10.267 42.772 1.00 44.25 ? 4359 HOH A O 1 HETATM 7360 O O . HOH J 5 . ? -5.205 7.787 3.781 1.00 44.74 ? 4360 HOH A O 1 HETATM 7361 O O . HOH J 5 . ? 3.667 -25.694 26.738 1.00 33.56 ? 4361 HOH A O 1 HETATM 7362 O O . HOH J 5 . ? -11.612 -45.207 50.457 1.00 27.47 ? 4362 HOH A O 1 HETATM 7363 O O . HOH J 5 . ? -4.244 2.834 38.894 1.00 22.34 ? 4363 HOH A O 1 HETATM 7364 O O . HOH J 5 . ? -12.278 0.666 49.450 1.00 42.07 ? 4364 HOH A O 1 HETATM 7365 O O . HOH J 5 . ? -34.374 -10.498 47.659 1.00 36.22 ? 4365 HOH A O 1 HETATM 7366 O O . HOH J 5 . ? -50.884 5.871 26.264 1.00 30.36 ? 4366 HOH A O 1 HETATM 7367 O O . HOH J 5 . ? 12.217 2.893 8.140 1.00 30.69 ? 4367 HOH A O 1 HETATM 7368 O O . HOH J 5 . ? -8.396 4.286 62.317 1.00 31.39 ? 4368 HOH A O 1 HETATM 7369 O O . HOH J 5 . ? -27.902 1.216 19.769 1.00 31.72 ? 4369 HOH A O 1 HETATM 7370 O O . HOH J 5 . ? -33.975 3.773 41.014 1.00 31.95 ? 4371 HOH A O 1 HETATM 7371 O O . HOH J 5 . ? 11.333 -12.514 60.598 1.00 40.78 ? 4372 HOH A O 1 HETATM 7372 O O . HOH J 5 . ? -0.881 -31.478 34.130 1.00 37.55 ? 4373 HOH A O 1 HETATM 7373 O O . HOH J 5 . ? -13.262 12.649 13.209 1.00 44.91 ? 4374 HOH A O 1 HETATM 7374 O O . HOH J 5 . ? 26.525 -20.765 35.197 1.00 36.08 ? 4375 HOH A O 1 HETATM 7375 O O . HOH J 5 . ? 9.205 4.304 4.537 1.00 40.37 ? 4376 HOH A O 1 HETATM 7376 O O . HOH J 5 . ? -9.629 10.631 20.564 1.00 27.20 ? 4377 HOH A O 1 HETATM 7377 O O . HOH J 5 . ? -15.450 -22.313 61.938 1.00 40.48 ? 4378 HOH A O 1 HETATM 7378 O O . HOH J 5 . ? 14.042 -10.445 53.278 1.00 43.37 ? 4379 HOH A O 1 HETATM 7379 O O . HOH J 5 . ? 13.411 -10.487 49.786 1.00 29.04 ? 4380 HOH A O 1 HETATM 7380 O O . HOH J 5 . ? 5.019 -3.932 1.361 1.00 37.16 ? 4381 HOH A O 1 HETATM 7381 O O . HOH J 5 . ? -29.457 -8.926 45.537 1.00 23.89 ? 4382 HOH A O 1 HETATM 7382 O O . HOH J 5 . ? -48.073 9.935 21.227 1.00 30.13 ? 4383 HOH A O 1 HETATM 7383 O O . HOH J 5 . ? -2.344 2.948 37.051 1.00 24.23 ? 4384 HOH A O 1 HETATM 7384 O O . HOH J 5 . ? -15.173 3.095 48.261 1.00 43.10 ? 4385 HOH A O 1 HETATM 7385 O O . HOH J 5 . ? 24.143 -26.717 41.192 1.00 34.16 ? 4386 HOH A O 1 HETATM 7386 O O . HOH J 5 . ? -10.239 -26.683 24.045 1.00 41.56 ? 4387 HOH A O 1 HETATM 7387 O O . HOH J 5 . ? 8.180 -15.638 73.689 1.00 32.80 ? 4388 HOH A O 1 HETATM 7388 O O . HOH J 5 . ? -28.506 -7.392 52.086 1.00 30.84 ? 4390 HOH A O 1 HETATM 7389 O O . HOH J 5 . ? -17.779 24.367 22.147 1.00 39.68 ? 4391 HOH A O 1 HETATM 7390 O O . HOH J 5 . ? 21.371 -24.726 36.107 1.00 32.16 ? 4392 HOH A O 1 HETATM 7391 O O . HOH J 5 . ? 10.519 -18.915 15.035 1.00 31.60 ? 4393 HOH A O 1 HETATM 7392 O O . HOH J 5 . ? -36.885 3.394 43.463 1.00 35.46 ? 4394 HOH A O 1 HETATM 7393 O O . HOH J 5 . ? -4.845 17.428 31.538 1.00 37.99 ? 4395 HOH A O 1 HETATM 7394 O O . HOH J 5 . ? -41.529 -5.876 37.768 1.00 31.08 ? 4396 HOH A O 1 HETATM 7395 O O . HOH J 5 . ? -8.562 7.905 23.157 1.00 23.95 ? 4397 HOH A O 1 HETATM 7396 O O . HOH J 5 . ? -11.455 -4.090 0.589 1.00 34.58 ? 4398 HOH A O 1 HETATM 7397 O O . HOH J 5 . ? -4.298 16.216 33.635 1.00 35.24 ? 4399 HOH A O 1 HETATM 7398 O O . HOH J 5 . ? -21.482 -24.983 13.167 1.00 33.70 ? 4401 HOH A O 1 HETATM 7399 O O . HOH J 5 . ? -26.752 3.589 18.395 1.00 31.08 ? 4402 HOH A O 1 HETATM 7400 O O . HOH J 5 . ? 4.508 -32.504 40.078 1.00 29.09 ? 4404 HOH A O 1 HETATM 7401 O O . HOH J 5 . ? -9.848 -9.163 0.560 1.00 34.77 ? 4405 HOH A O 1 HETATM 7402 O O . HOH J 5 . ? -48.996 14.162 35.860 1.00 47.88 ? 4406 HOH A O 1 HETATM 7403 O O . HOH J 5 . ? 0.172 1.618 48.307 1.00 29.13 ? 4407 HOH A O 1 HETATM 7404 O O . HOH J 5 . ? 4.034 -4.676 62.659 1.00 32.18 ? 4408 HOH A O 1 HETATM 7405 O O . HOH J 5 . ? 8.845 -26.571 71.731 1.00 44.68 ? 4409 HOH A O 1 HETATM 7406 O O . HOH J 5 . ? -23.310 17.293 20.290 1.00 36.95 ? 4410 HOH A O 1 HETATM 7407 O O . HOH J 5 . ? 8.388 -18.206 41.107 1.00 20.48 ? 4411 HOH A O 1 HETATM 7408 O O . HOH J 5 . ? -3.451 1.456 50.131 1.00 32.89 ? 4412 HOH A O 1 HETATM 7409 O O . HOH J 5 . ? -20.478 -31.320 46.440 1.00 57.29 ? 4413 HOH A O 1 HETATM 7410 O O . HOH J 5 . ? -14.035 10.807 27.680 1.00 22.51 ? 4414 HOH A O 1 HETATM 7411 O O . HOH J 5 . ? -16.417 -27.919 22.120 1.00 28.54 ? 4415 HOH A O 1 HETATM 7412 O O . HOH J 5 . ? -19.509 -25.343 14.969 1.00 31.15 ? 4416 HOH A O 1 HETATM 7413 O O . HOH J 5 . ? -5.647 -24.417 67.401 1.00 41.41 ? 4417 HOH A O 1 HETATM 7414 O O . HOH J 5 . ? -21.214 4.342 40.632 1.00 35.46 ? 4418 HOH A O 1 HETATM 7415 O O . HOH J 5 . ? -25.668 -7.076 55.876 1.00 46.77 ? 4419 HOH A O 1 HETATM 7416 O O . HOH J 5 . ? -10.072 -27.554 12.388 1.00 39.46 ? 4420 HOH A O 1 HETATM 7417 O O . HOH J 5 . ? 18.205 -33.835 37.608 1.00 26.50 ? 4421 HOH A O 1 HETATM 7418 O O . HOH J 5 . ? 7.688 -22.335 25.685 1.00 30.53 ? 4422 HOH A O 1 HETATM 7419 O O . HOH J 5 . ? -10.668 -41.963 49.653 1.00 26.79 ? 4423 HOH A O 1 HETATM 7420 O O . HOH J 5 . ? -0.487 -29.313 27.250 1.00 53.63 ? 4424 HOH A O 1 HETATM 7421 O O . HOH J 5 . ? -15.249 21.068 39.677 1.00 34.73 ? 4425 HOH A O 1 HETATM 7422 O O . HOH J 5 . ? 16.611 5.346 28.198 1.00 33.72 ? 4426 HOH A O 1 HETATM 7423 O O . HOH J 5 . ? -13.821 -5.416 0.318 1.00 41.37 ? 4427 HOH A O 1 HETATM 7424 O O . HOH J 5 . ? 7.239 -24.114 23.588 1.00 43.42 ? 4428 HOH A O 1 HETATM 7425 O O . HOH J 5 . ? -13.578 -26.747 37.699 1.00 36.49 ? 4430 HOH A O 1 HETATM 7426 O O . HOH J 5 . ? -8.510 10.670 23.355 1.00 29.63 ? 4431 HOH A O 1 HETATM 7427 O O . HOH J 5 . ? -25.721 -12.426 57.917 1.00 43.64 ? 4432 HOH A O 1 HETATM 7428 O O . HOH J 5 . ? -18.023 -19.755 59.342 1.00 31.21 ? 4433 HOH A O 1 HETATM 7429 O O . HOH J 5 . ? -15.558 -0.120 57.719 1.00 28.47 ? 4434 HOH A O 1 HETATM 7430 O O . HOH J 5 . ? -35.309 -8.107 20.534 1.00 33.93 ? 4435 HOH A O 1 HETATM 7431 O O . HOH J 5 . ? 4.478 -28.068 61.510 1.00 33.75 ? 4436 HOH A O 1 HETATM 7432 O O . HOH J 5 . ? -2.101 -31.573 29.661 1.00 47.64 ? 4437 HOH A O 1 HETATM 7433 O O . HOH J 5 . ? 13.985 -20.687 63.017 1.00 29.60 ? 4438 HOH A O 1 HETATM 7434 O O . HOH J 5 . ? 3.357 -29.978 28.040 1.00 41.76 ? 4439 HOH A O 1 HETATM 7435 O O . HOH J 5 . ? 6.187 2.245 38.408 1.00 42.85 ? 4440 HOH A O 1 HETATM 7436 O O . HOH J 5 . ? -13.956 -22.053 39.529 1.00 22.77 ? 4441 HOH A O 1 HETATM 7437 O O . HOH J 5 . ? 15.322 6.292 30.332 1.00 32.88 ? 4442 HOH A O 1 HETATM 7438 O O . HOH J 5 . ? 15.187 -23.317 62.128 1.00 34.16 ? 4443 HOH A O 1 HETATM 7439 O O . HOH J 5 . ? -44.074 -0.618 18.729 1.00 53.13 ? 4444 HOH A O 1 HETATM 7440 O O . HOH J 5 . ? -38.675 -6.910 22.407 1.00 40.50 ? 4445 HOH A O 1 HETATM 7441 O O . HOH J 5 . ? 16.244 -4.732 9.914 1.00 36.38 ? 4446 HOH A O 1 HETATM 7442 O O . HOH J 5 . ? -15.382 -17.688 5.517 1.00 46.65 ? 4447 HOH A O 1 HETATM 7443 O O . HOH J 5 . ? -33.408 6.086 42.296 1.00 53.12 ? 4448 HOH A O 1 HETATM 7444 O O . HOH J 5 . ? -26.441 -16.702 6.755 1.00 46.73 ? 4449 HOH A O 1 HETATM 7445 O O . HOH J 5 . ? 2.414 4.310 0.343 1.00 38.26 ? 4450 HOH A O 1 HETATM 7446 O O . HOH J 5 . ? -34.895 0.166 41.912 1.00 36.17 ? 4451 HOH A O 1 HETATM 7447 O O . HOH J 5 . ? 27.522 -7.379 21.275 1.00 42.42 ? 4452 HOH A O 1 HETATM 7448 O O . HOH J 5 . ? 3.572 2.966 43.686 1.00 42.49 ? 4453 HOH A O 1 HETATM 7449 O O . HOH J 5 . ? 2.869 7.476 18.584 1.00 32.42 ? 4454 HOH A O 1 HETATM 7450 O O . HOH J 5 . ? -22.718 -8.631 67.405 1.00 39.42 ? 4455 HOH A O 1 HETATM 7451 O O . HOH J 5 . ? 5.398 -0.993 68.051 1.00 31.85 ? 4456 HOH A O 1 HETATM 7452 O O . HOH J 5 . ? -17.879 -4.422 2.500 1.00 40.72 ? 4457 HOH A O 1 HETATM 7453 O O . HOH J 5 . ? 25.856 -0.255 19.827 1.00 41.87 ? 4458 HOH A O 1 HETATM 7454 O O . HOH J 5 . ? 15.456 -18.987 52.315 1.00 45.79 ? 4459 HOH A O 1 HETATM 7455 O O . HOH J 5 . ? -27.145 -18.415 32.751 1.00 27.85 ? 4460 HOH A O 1 HETATM 7456 O O . HOH J 5 . ? -33.637 0.623 44.700 1.00 45.42 ? 4463 HOH A O 1 HETATM 7457 O O . HOH J 5 . ? -45.934 0.463 17.276 1.00 39.98 ? 4464 HOH A O 1 HETATM 7458 O O . HOH J 5 . ? -4.037 1.215 6.849 1.00 35.33 ? 4465 HOH A O 1 HETATM 7459 O O . HOH J 5 . ? -9.190 -5.698 0.915 1.00 31.81 ? 4466 HOH A O 1 HETATM 7460 O O . HOH J 5 . ? 15.555 -22.023 49.363 1.00 37.26 ? 4467 HOH A O 1 HETATM 7461 O O . HOH J 5 . ? -20.826 -23.581 38.918 1.00 47.86 ? 4468 HOH A O 1 HETATM 7462 O O . HOH J 5 . ? -17.812 -34.278 48.299 1.00 48.28 ? 4469 HOH A O 1 HETATM 7463 O O . HOH J 5 . ? -5.243 9.755 14.180 1.00 38.84 ? 4470 HOH A O 1 HETATM 7464 O O . HOH J 5 . ? -32.557 -7.501 43.328 1.00 31.22 ? 4471 HOH A O 1 HETATM 7465 O O . HOH J 5 . ? -33.697 8.791 41.650 1.00 34.29 ? 4472 HOH A O 1 HETATM 7466 O O . HOH J 5 . ? -28.913 14.145 39.601 1.00 29.89 ? 4473 HOH A O 1 HETATM 7467 O O . HOH J 5 . ? 20.670 -11.854 42.518 1.00 40.62 ? 4474 HOH A O 1 HETATM 7468 O O . HOH J 5 . ? -30.400 3.183 22.362 1.00 50.91 ? 4475 HOH A O 1 HETATM 7469 O O . HOH J 5 . ? -5.202 -25.649 20.856 1.00 38.58 ? 4476 HOH A O 1 HETATM 7470 O O . HOH J 5 . ? 2.594 -32.622 43.020 1.00 33.93 ? 4477 HOH A O 1 HETATM 7471 O O . HOH J 5 . ? -31.582 2.936 41.099 1.00 34.01 ? 4478 HOH A O 1 HETATM 7472 O O . HOH J 5 . ? -11.132 20.126 41.607 1.00 39.66 ? 4479 HOH A O 1 HETATM 7473 O O . HOH J 5 . ? 27.028 -9.057 28.823 1.00 48.73 ? 4480 HOH A O 1 HETATM 7474 O O . HOH J 5 . ? 1.570 2.714 56.701 1.00 45.38 ? 4481 HOH A O 1 HETATM 7475 O O . HOH J 5 . ? -28.668 -1.074 17.312 1.00 40.57 ? 4482 HOH A O 1 HETATM 7476 O O . HOH J 5 . ? 21.831 -21.671 43.543 1.00 49.14 ? 4484 HOH A O 1 HETATM 7477 O O . HOH J 5 . ? -31.802 23.951 26.488 1.00 44.41 ? 4485 HOH A O 1 HETATM 7478 O O . HOH J 5 . ? 6.046 -4.280 70.882 1.00 37.32 ? 4486 HOH A O 1 HETATM 7479 O O . HOH J 5 . ? -25.695 3.903 39.138 1.00 41.32 ? 4487 HOH A O 1 HETATM 7480 O O . HOH J 5 . ? 4.985 -8.320 -0.375 1.00 44.39 ? 4488 HOH A O 1 HETATM 7481 O O . HOH J 5 . ? 23.461 0.718 25.747 1.00 36.96 ? 4489 HOH A O 1 HETATM 7482 O O . HOH J 5 . ? -6.370 3.825 60.174 1.00 37.28 ? 4490 HOH A O 1 HETATM 7483 O O . HOH J 5 . ? -17.614 -2.842 56.095 1.00 34.61 ? 4491 HOH A O 1 HETATM 7484 O O . HOH J 5 . ? -5.367 -27.060 18.802 1.00 47.40 ? 4493 HOH A O 1 HETATM 7485 O O . HOH J 5 . ? -28.519 3.459 42.267 1.00 43.96 ? 4494 HOH A O 1 HETATM 7486 O O . HOH J 5 . ? 5.900 14.244 30.254 1.00 45.49 ? 4495 HOH A O 1 HETATM 7487 O O . HOH J 5 . ? 4.224 -34.474 43.897 1.00 38.29 ? 4496 HOH A O 1 HETATM 7488 O O . HOH J 5 . ? 16.201 -12.375 46.823 1.00 39.47 ? 4497 HOH A O 1 HETATM 7489 O O . HOH J 5 . ? 14.389 2.812 35.684 1.00 33.78 ? 4498 HOH A O 1 HETATM 7490 O O . HOH J 5 . ? -4.165 0.597 4.317 1.00 63.06 ? 4499 HOH A O 1 HETATM 7491 O O . HOH J 5 . ? 6.802 -46.417 58.608 1.00 35.91 ? 4500 HOH A O 1 HETATM 7492 O O . HOH J 5 . ? -2.518 16.603 28.028 1.00 42.10 ? 4501 HOH A O 1 HETATM 7493 O O . HOH J 5 . ? -21.124 3.722 34.371 1.00 32.06 ? 4502 HOH A O 1 HETATM 7494 O O . HOH J 5 . ? -17.800 11.340 14.538 1.00 42.44 ? 4503 HOH A O 1 HETATM 7495 O O . HOH J 5 . ? 26.231 -18.875 22.367 1.00 44.02 ? 4504 HOH A O 1 HETATM 7496 O O . HOH J 5 . ? -8.836 -18.030 4.599 1.00 29.80 ? 4505 HOH A O 1 HETATM 7497 O O . HOH J 5 . ? -5.528 7.644 15.259 1.00 36.23 ? 4506 HOH A O 1 HETATM 7498 O O . HOH J 5 . ? 7.421 -34.597 32.398 1.00 36.43 ? 4507 HOH A O 1 HETATM 7499 O O . HOH J 5 . ? -18.849 -28.947 47.982 1.00 36.98 ? 4508 HOH A O 1 HETATM 7500 O O . HOH J 5 . ? -35.154 25.873 27.525 1.00 46.17 ? 4509 HOH A O 1 HETATM 7501 O O . HOH J 5 . ? -12.470 -29.160 24.548 1.00 36.62 ? 4510 HOH A O 1 HETATM 7502 O O . HOH J 5 . ? -9.815 0.880 34.811 1.00 27.65 ? 4511 HOH A O 1 HETATM 7503 O O . HOH J 5 . ? -17.529 -10.574 0.072 1.00 35.29 ? 4512 HOH A O 1 HETATM 7504 O O . HOH J 5 . ? 9.222 -25.693 22.908 1.00 45.59 ? 4513 HOH A O 1 HETATM 7505 O O . HOH J 5 . ? -31.590 -8.956 22.876 1.00 33.21 ? 4514 HOH A O 1 HETATM 7506 O O . HOH J 5 . ? -43.962 7.313 44.893 1.00 49.47 ? 4515 HOH A O 1 HETATM 7507 O O . HOH J 5 . ? -18.379 -18.470 5.820 1.00 44.56 ? 4516 HOH A O 1 HETATM 7508 O O . HOH J 5 . ? 7.960 -34.847 46.610 1.00 36.43 ? 4517 HOH A O 1 HETATM 7509 O O . HOH J 5 . ? -12.081 -26.352 12.904 1.00 32.57 ? 4518 HOH A O 1 HETATM 7510 O O . HOH J 5 . ? -13.934 -29.130 38.535 1.00 53.14 ? 4519 HOH A O 1 HETATM 7511 O O . HOH J 5 . ? -28.697 -15.546 6.877 1.00 45.67 ? 4520 HOH A O 1 HETATM 7512 O O . HOH J 5 . ? -39.034 -19.456 29.231 1.00 35.04 ? 4521 HOH A O 1 HETATM 7513 O O . HOH J 5 . ? -35.122 22.155 24.355 1.00 37.00 ? 4522 HOH A O 1 HETATM 7514 O O . HOH J 5 . ? -8.627 20.821 41.603 1.00 46.05 ? 4523 HOH A O 1 HETATM 7515 O O . HOH J 5 . ? -21.817 -30.266 44.589 1.00 43.04 ? 4524 HOH A O 1 HETATM 7516 O O . HOH J 5 . ? -39.334 10.941 37.240 1.00 31.74 ? 4525 HOH A O 1 HETATM 7517 O O . HOH J 5 . ? -39.905 -2.161 18.321 1.00 43.58 ? 4527 HOH A O 1 HETATM 7518 O O . HOH J 5 . ? -31.854 -6.500 22.093 1.00 42.38 ? 4528 HOH A O 1 HETATM 7519 O O . HOH J 5 . ? 16.387 4.478 36.595 1.00 43.85 ? 4529 HOH A O 1 HETATM 7520 O O . HOH J 5 . ? -51.042 18.230 31.645 1.00 49.67 ? 4530 HOH A O 1 HETATM 7521 O O . HOH J 5 . ? -34.382 -6.715 45.715 1.00 44.34 ? 4531 HOH A O 1 HETATM 7522 O O . HOH J 5 . ? -6.642 5.726 42.106 1.00 36.89 ? 4532 HOH A O 1 HETATM 7523 O O . HOH J 5 . ? 11.710 -13.077 36.921 1.00 37.38 ? 4533 HOH A O 1 HETATM 7524 O O . HOH J 5 . ? -33.730 -12.211 14.552 1.00 38.84 ? 4534 HOH A O 1 HETATM 7525 O O . HOH J 5 . ? 25.239 -1.649 17.740 1.00 35.61 ? 4535 HOH A O 1 HETATM 7526 O O . HOH J 5 . ? -40.732 -4.215 19.002 1.00 40.04 ? 4536 HOH A O 1 HETATM 7527 O O . HOH J 5 . ? 13.499 -9.856 4.646 1.00 38.67 ? 4537 HOH A O 1 HETATM 7528 O O . HOH J 5 . ? -34.883 -18.030 41.226 1.00 42.40 ? 4538 HOH A O 1 HETATM 7529 O O . HOH J 5 . ? -35.085 -11.943 23.916 1.00 47.26 ? 4539 HOH A O 1 HETATM 7530 O O . HOH J 5 . ? 18.461 -24.035 20.938 1.00 37.85 ? 4540 HOH A O 1 HETATM 7531 O O . HOH J 5 . ? -9.360 7.204 43.848 1.00 26.64 ? 4541 HOH A O 1 HETATM 7532 O O . HOH J 5 . ? -45.131 -5.913 22.797 1.00 48.34 ? 4542 HOH A O 1 HETATM 7533 O O . HOH J 5 . ? 15.545 -30.514 51.783 1.00 41.75 ? 4543 HOH A O 1 HETATM 7534 O O . HOH J 5 . ? -21.435 -12.065 1.276 1.00 33.85 ? 4544 HOH A O 1 HETATM 7535 O O . HOH J 5 . ? -15.913 0.289 60.450 1.00 45.38 ? 4545 HOH A O 1 HETATM 7536 O O . HOH J 5 . ? 9.201 -13.792 5.812 1.00 36.87 ? 4546 HOH A O 1 HETATM 7537 O O . HOH J 5 . ? -17.953 19.164 28.101 1.00 35.26 ? 4547 HOH A O 1 HETATM 7538 O O . HOH J 5 . ? -14.531 -44.557 48.063 1.00 47.48 ? 4548 HOH A O 1 HETATM 7539 O O . HOH J 5 . ? -26.912 27.154 26.765 1.00 49.31 ? 4549 HOH A O 1 HETATM 7540 O O . HOH J 5 . ? -22.689 -5.774 4.787 1.00 36.89 ? 4550 HOH A O 1 HETATM 7541 O O . HOH J 5 . ? 6.648 -5.508 62.917 1.00 37.96 ? 4551 HOH A O 1 HETATM 7542 O O . HOH J 5 . ? 4.675 9.653 21.216 1.00 40.74 ? 4552 HOH A O 1 HETATM 7543 O O . HOH J 5 . ? -14.962 -2.830 52.668 1.00 42.84 ? 4553 HOH A O 1 HETATM 7544 O O . HOH J 5 . ? -16.584 24.346 24.998 1.00 35.22 ? 4554 HOH A O 1 HETATM 7545 O O . HOH J 5 . ? 15.319 -22.333 56.393 1.00 41.36 ? 4555 HOH A O 1 HETATM 7546 O O . HOH J 5 . ? 15.749 -12.052 49.480 1.00 43.67 ? 4556 HOH A O 1 HETATM 7547 O O . HOH J 5 . ? 3.693 10.024 31.394 1.00 38.17 ? 4557 HOH A O 1 HETATM 7548 O O . HOH J 5 . ? -16.498 13.495 13.448 1.00 40.94 ? 4558 HOH A O 1 HETATM 7549 O O . HOH J 5 . ? 8.293 -3.594 47.749 1.00 26.27 ? 4559 HOH A O 1 HETATM 7550 O O . HOH J 5 . ? 2.204 10.522 22.453 1.00 37.96 ? 4562 HOH A O 1 HETATM 7551 O O . HOH J 5 . ? -2.447 14.839 33.989 1.00 44.48 ? 4563 HOH A O 1 HETATM 7552 O O . HOH J 5 . ? 2.662 -36.679 65.222 1.00 56.14 ? 4564 HOH A O 1 HETATM 7553 O O . HOH J 5 . ? 11.032 -12.069 4.645 1.00 41.64 ? 4565 HOH A O 1 HETATM 7554 O O . HOH J 5 . ? 5.677 11.342 30.276 1.00 41.41 ? 4567 HOH A O 1 HETATM 7555 O O . HOH J 5 . ? -8.495 -30.189 27.025 1.00 35.74 ? 4568 HOH A O 1 HETATM 7556 O O . HOH J 5 . ? -53.286 19.403 32.822 1.00 44.50 ? 4569 HOH A O 1 HETATM 7557 O O . HOH J 5 . ? -22.234 -30.603 21.072 1.00 48.20 ? 4570 HOH A O 1 HETATM 7558 O O . HOH J 5 . ? 13.694 -31.072 29.311 1.00 33.59 ? 4571 HOH A O 1 HETATM 7559 O O . HOH J 5 . ? 2.683 12.930 23.841 1.00 40.03 ? 4572 HOH A O 1 HETATM 7560 O O . HOH J 5 . ? 22.932 -23.164 41.584 1.00 43.73 ? 4574 HOH A O 1 HETATM 7561 O O . HOH J 5 . ? 6.458 -0.642 47.033 1.00 33.37 ? 4575 HOH A O 1 HETATM 7562 O O . HOH J 5 . ? -25.100 -26.149 13.920 1.00 33.59 ? 4576 HOH A O 1 HETATM 7563 O O . HOH J 5 . ? 7.020 -21.318 14.223 1.00 42.69 ? 4577 HOH A O 1 HETATM 7564 O O . HOH J 5 . ? 15.840 -21.239 60.168 1.00 42.25 ? 4578 HOH A O 1 HETATM 7565 O O . HOH J 5 . ? -20.646 -4.830 4.137 1.00 39.92 ? 4579 HOH A O 1 HETATM 7566 O O . HOH J 5 . ? -18.394 22.655 32.229 1.00 43.79 ? 4581 HOH A O 1 HETATM 7567 O O . HOH J 5 . ? -37.547 9.835 18.252 1.00 42.33 ? 4582 HOH A O 1 HETATM 7568 O O . HOH J 5 . ? 22.906 -2.819 35.431 1.00 41.91 ? 4583 HOH A O 1 HETATM 7569 O O . HOH J 5 . ? 3.511 -42.658 63.732 1.00 40.08 ? 4584 HOH A O 1 HETATM 7570 O O . HOH J 5 . ? 9.536 -2.913 43.412 1.00 36.72 ? 4585 HOH A O 1 HETATM 7571 O O . HOH J 5 . ? 15.411 9.494 21.254 1.00 51.15 ? 4586 HOH A O 1 HETATM 7572 O O . HOH J 5 . ? -7.258 -4.297 -0.665 1.00 39.71 ? 4587 HOH A O 1 HETATM 7573 O O . HOH J 5 . ? 18.998 -0.835 16.118 1.00 41.25 ? 4588 HOH A O 1 HETATM 7574 O O . HOH J 5 . ? 10.318 -3.388 36.081 1.00 40.79 ? 4589 HOH A O 1 HETATM 7575 O O . HOH J 5 . ? -6.603 2.231 7.590 1.00 30.13 ? 4591 HOH A O 1 HETATM 7576 O O . HOH J 5 . ? -13.675 -25.671 10.819 1.00 43.81 ? 4593 HOH A O 1 HETATM 7577 O O . HOH J 5 . ? 23.328 -11.257 41.858 1.00 56.69 ? 4594 HOH A O 1 HETATM 7578 O O . HOH J 5 . ? -8.950 21.944 34.349 1.00 35.60 ? 4595 HOH A O 1 HETATM 7579 O O . HOH J 5 . ? 3.648 -39.190 65.899 1.00 37.99 ? 4596 HOH A O 1 HETATM 7580 O O . HOH J 5 . ? -4.746 19.837 32.236 1.00 40.57 ? 4597 HOH A O 1 HETATM 7581 O O . HOH J 5 . ? -1.358 -25.670 64.564 1.00 36.02 ? 4598 HOH A O 1 HETATM 7582 O O . HOH J 5 . ? 16.714 -26.419 52.683 1.00 48.37 ? 4599 HOH A O 1 HETATM 7583 O O . HOH J 5 . ? -18.038 0.743 48.575 1.00 35.96 ? 4600 HOH A O 1 HETATM 7584 O O . HOH J 5 . ? 7.027 -5.355 74.287 1.00 51.30 ? 4601 HOH A O 1 HETATM 7585 O O . HOH J 5 . ? 15.004 -29.032 23.328 1.00 37.32 ? 4602 HOH A O 1 HETATM 7586 O O . HOH J 5 . ? -17.429 -2.026 53.634 1.00 37.15 ? 4603 HOH A O 1 HETATM 7587 O O . HOH J 5 . ? 12.108 -11.140 58.314 1.00 44.22 ? 4604 HOH A O 1 HETATM 7588 O O . HOH J 5 . ? 4.492 -21.171 76.310 1.00 39.04 ? 4605 HOH A O 1 HETATM 7589 O O . HOH J 5 . ? 21.403 -27.872 46.021 1.00 35.05 ? 4606 HOH A O 1 HETATM 7590 O O . HOH J 5 . ? 9.888 -32.837 43.663 1.00 36.29 ? 4607 HOH A O 1 HETATM 7591 O O . HOH J 5 . ? -35.260 -18.617 18.197 1.00 50.72 ? 4608 HOH A O 1 HETATM 7592 O O . HOH J 5 . ? -37.707 4.528 18.161 1.00 30.71 ? 4609 HOH A O 1 HETATM 7593 O O . HOH J 5 . ? 15.665 5.093 15.129 1.00 38.49 ? 4610 HOH A O 1 HETATM 7594 O O . HOH J 5 . ? 18.992 5.934 27.665 1.00 40.81 ? 4611 HOH A O 1 HETATM 7595 O O . HOH J 5 . ? 12.978 -32.924 42.821 1.00 37.32 ? 4612 HOH A O 1 HETATM 7596 O O . HOH J 5 . ? 11.664 -1.457 36.361 1.00 44.04 ? 4613 HOH A O 1 HETATM 7597 O O . HOH J 5 . ? -19.045 -2.354 58.265 1.00 48.28 ? 4614 HOH A O 1 HETATM 7598 O O . HOH J 5 . ? -38.366 -7.852 34.962 1.00 31.99 ? 4615 HOH A O 1 HETATM 7599 O O . HOH J 5 . ? -5.030 -2.917 -0.006 1.00 51.24 ? 4616 HOH A O 1 HETATM 7600 O O . HOH J 5 . ? -50.405 -0.289 25.998 1.00 48.91 ? 4617 HOH A O 1 HETATM 7601 O O . HOH J 5 . ? -9.091 14.082 22.996 1.00 39.28 ? 4618 HOH A O 1 HETATM 7602 O O . HOH J 5 . ? -8.170 -19.583 14.645 1.00 12.40 ? 4619 HOH A O 1 HETATM 7603 O O . HOH J 5 . ? -43.304 11.301 36.203 1.00 39.34 ? 4622 HOH A O 1 HETATM 7604 O O . HOH J 5 . ? -1.097 -0.234 54.704 1.00 30.98 ? 4624 HOH A O 1 HETATM 7605 O O . HOH J 5 . ? -32.552 1.792 23.619 1.00 60.09 ? 4625 HOH A O 1 HETATM 7606 O O . HOH J 5 . ? -5.763 -0.663 1.124 1.00 43.94 ? 4628 HOH A O 1 HETATM 7607 O O . HOH J 5 . ? 7.072 -0.968 59.135 1.00 51.86 ? 4629 HOH A O 1 HETATM 7608 O O . HOH J 5 . ? -38.730 23.997 27.739 1.00 37.40 ? 4630 HOH A O 1 HETATM 7609 O O . HOH J 5 . ? -19.269 1.825 46.189 1.00 44.39 ? 4631 HOH A O 1 HETATM 7610 O O . HOH J 5 . ? -28.176 24.264 24.885 1.00 41.56 ? 4632 HOH A O 1 HETATM 7611 O O . HOH J 5 . ? 12.838 -35.437 39.668 1.00 43.84 ? 4633 HOH A O 1 HETATM 7612 O O . HOH J 5 . ? 0.929 -38.698 65.244 1.00 43.05 ? 4634 HOH A O 1 HETATM 7613 O O . HOH J 5 . ? -33.999 -11.554 20.260 1.00 46.04 ? 4635 HOH A O 1 HETATM 7614 O O . HOH J 5 . ? 5.218 11.116 7.977 1.00 38.73 ? 4636 HOH A O 1 HETATM 7615 O O . HOH J 5 . ? 2.498 -33.934 40.820 1.00 42.10 ? 4637 HOH A O 1 HETATM 7616 O O . HOH J 5 . ? -3.394 8.451 15.808 1.00 44.79 ? 4638 HOH A O 1 HETATM 7617 O O . HOH J 5 . ? -11.895 6.952 8.122 1.00 47.14 ? 4639 HOH A O 1 HETATM 7618 O O . HOH J 5 . ? 13.529 -2.382 35.159 1.00 40.73 ? 4640 HOH A O 1 HETATM 7619 O O . HOH J 5 . ? -40.869 -6.700 35.186 1.00 38.65 ? 4641 HOH A O 1 HETATM 7620 O O . HOH J 5 . ? -17.368 -30.159 57.153 1.00 36.91 ? 4642 HOH A O 1 HETATM 7621 O O . HOH J 5 . ? -48.254 6.229 20.910 1.00 40.21 ? 4643 HOH A O 1 HETATM 7622 O O . HOH J 5 . ? -11.708 -29.108 37.313 1.00 55.38 ? 4644 HOH A O 1 HETATM 7623 O O . HOH J 5 . ? 16.383 7.339 16.347 1.00 50.45 ? 4645 HOH A O 1 HETATM 7624 O O . HOH J 5 . ? -20.441 23.574 23.927 1.00 41.15 ? 4653 HOH A O 1 HETATM 7625 O O . HOH J 5 . ? -35.426 -12.001 17.895 1.00 40.46 ? 4657 HOH A O 1 HETATM 7626 O O . HOH J 5 . ? -2.836 1.517 53.016 1.00 35.28 ? 4659 HOH A O 1 HETATM 7627 O O . HOH J 5 . ? 13.506 4.715 33.700 1.00 41.40 ? 4662 HOH A O 1 HETATM 7628 O O . HOH J 5 . ? -25.461 -28.237 21.151 1.00 42.92 ? 4663 HOH A O 1 HETATM 7629 O O . HOH J 5 . ? 5.207 7.186 10.351 1.00 44.75 ? 4665 HOH A O 1 HETATM 7630 O O . HOH J 5 . ? -23.657 -22.076 48.335 1.00 35.11 ? 4666 HOH A O 1 HETATM 7631 O O . HOH J 5 . ? -21.474 16.704 18.574 1.00 32.95 ? 4667 HOH A O 1 HETATM 7632 O O . HOH J 5 . ? -14.003 -26.977 16.395 1.00 47.78 ? 4668 HOH A O 1 HETATM 7633 O O . HOH J 5 . ? -50.598 17.128 34.692 1.00 51.17 ? 4669 HOH A O 1 HETATM 7634 O O . HOH J 5 . ? -21.215 1.570 44.867 1.00 45.85 ? 4670 HOH A O 1 HETATM 7635 O O . HOH J 5 . ? -6.858 -34.764 62.661 1.00 45.25 ? 4671 HOH A O 1 HETATM 7636 O O . HOH J 5 . ? -0.069 -32.151 44.823 1.00 41.20 ? 4672 HOH A O 1 HETATM 7637 O O . HOH J 5 . ? -3.080 -43.922 62.099 1.00 33.83 ? 4673 HOH A O 1 HETATM 7638 O O . HOH J 5 . ? 11.427 -25.986 68.309 1.00 61.89 ? 4674 HOH A O 1 HETATM 7639 O O . HOH J 5 . ? -19.686 -0.986 45.321 1.00 46.21 ? 4675 HOH A O 1 HETATM 7640 O O . HOH J 5 . ? 29.369 -12.578 17.290 1.00 48.97 ? 4676 HOH A O 1 HETATM 7641 O O . HOH J 5 . ? -19.680 -28.824 50.961 1.00 34.60 ? 4677 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 ? ? ? A . n A 1 2 ALA 2 2 ? ? ? A . n A 1 3 GLU 3 3 ? ? ? A . n A 1 4 CYS 4 4 ? ? ? A . n A 1 5 PRO 5 5 ? ? ? A . n A 1 6 VAL 6 6 ? ? ? A . n A 1 7 VAL 7 7 7 VAL VAL A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 GLU 9 9 9 GLU GLU A . n A 1 10 LEU 10 10 10 LEU LEU A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 ARG 12 12 12 ARG ARG A . n A 1 13 ILE 13 13 13 ILE ILE A . n A 1 14 ASN 14 14 14 ASN ASN A . n A 1 15 CYS 15 15 15 CYS CYS A . n A 1 16 ILE 16 16 16 ILE ILE A . n A 1 17 PRO 17 17 17 PRO PRO A . n A 1 18 ASP 18 18 18 ASP ASP A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 PRO 20 20 20 PRO PRO A . n A 1 21 PRO 21 21 21 PRO PRO A . n A 1 22 THR 22 22 22 THR THR A . n A 1 23 LYS 23 23 23 LYS LYS A . n A 1 24 ALA 24 24 24 ALA ALA A . n A 1 25 THR 25 25 25 THR THR A . n A 1 26 CYS 26 26 26 CYS CYS A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 GLN 28 28 28 GLN GLN A . n A 1 29 ARG 29 29 29 ARG ARG A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 CYS 32 32 32 CYS CYS A . n A 1 33 TRP 33 33 33 TRP TRP A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 PRO 35 35 35 PRO PRO A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 ALA 38 38 38 ALA ALA A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 SER 40 40 40 SER SER A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 TRP 43 43 43 TRP TRP A . n A 1 44 CYS 44 44 44 CYS CYS A . n A 1 45 TYR 45 45 45 TYR TYR A . n A 1 46 TYR 46 46 46 TYR TYR A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 ASN 49 49 49 ASN ASN A . n A 1 50 HIS 50 50 50 HIS HIS A . n A 1 51 SER 51 51 51 SER SER A . n A 1 52 TYR 52 52 52 TYR TYR A . n A 1 53 HIS 53 53 53 HIS HIS A . n A 1 54 VAL 54 54 54 VAL VAL A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 LEU 58 58 58 LEU LEU A . n A 1 59 VAL 59 59 59 VAL VAL A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 THR 61 61 61 THR THR A . n A 1 62 ASN 62 62 62 ASN ASN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 PHE 65 65 65 PHE PHE A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ALA 67 67 67 ALA ALA A . n A 1 68 ARG 68 68 68 ARG ARG A . n A 1 69 LEU 69 69 69 LEU LEU A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 ASN 71 71 71 ASN ASN A . n A 1 72 LEU 72 72 72 LEU LEU A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 SER 74 74 74 SER SER A . n A 1 75 SER 75 75 75 SER SER A . n A 1 76 PRO 76 76 76 PRO PRO A . n A 1 77 VAL 77 77 77 VAL VAL A . n A 1 78 PHE 78 78 78 PHE PHE A . n A 1 79 GLY 79 79 79 GLY GLY A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 ASN 81 81 81 ASN ASN A . n A 1 82 VAL 82 82 82 VAL VAL A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 LEU 86 86 86 LEU LEU A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 THR 88 88 88 THR THR A . n A 1 89 ALA 89 89 89 ALA ALA A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 TYR 91 91 91 TYR TYR A . n A 1 92 GLN 92 92 92 GLN GLN A . n A 1 93 THR 93 93 93 THR THR A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 ASN 95 95 95 ASN ASN A . n A 1 96 ARG 96 96 96 ARG ARG A . n A 1 97 PHE 97 97 97 PHE PHE A . n A 1 98 HIS 98 98 98 HIS HIS A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 LYS 100 100 100 LYS LYS A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 THR 102 102 102 THR THR A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 ARG 108 108 108 ARG ARG A . n A 1 109 PHE 109 109 109 PHE PHE A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 PRO 112 112 112 PRO PRO A . n A 1 113 HIS 113 113 113 HIS HIS A . n A 1 114 GLU 114 114 114 GLU GLU A . n A 1 115 HIS 115 115 115 HIS HIS A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 GLN 117 117 117 GLN GLN A . n A 1 118 SER 118 118 118 SER SER A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 ASN 122 122 122 ASN ASN A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 ALA 124 124 124 ALA ALA A . n A 1 125 ALA 125 125 125 ALA ALA A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 TYR 129 129 129 TYR TYR A . n A 1 130 GLN 130 130 130 GLN GLN A . n A 1 131 VAL 131 131 131 VAL VAL A . n A 1 132 GLU 132 132 132 GLU GLU A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 GLN 136 136 136 GLN GLN A . n A 1 137 PRO 137 137 137 PRO PRO A . n A 1 138 PHE 138 138 138 PHE PHE A . n A 1 139 SER 139 139 139 SER SER A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 LYS 141 141 141 LYS LYS A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 THR 143 143 143 THR THR A . n A 1 144 ARG 144 144 144 ARG ARG A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 ASN 147 147 147 ASN ASN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 ARG 149 149 149 ARG ARG A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 SER 154 154 154 SER SER A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 ILE 156 156 156 ILE ILE A . n A 1 157 GLY 157 157 157 GLY GLY A . n A 1 158 PRO 158 158 158 PRO PRO A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LEU 160 160 160 LEU LEU A . n A 1 161 PHE 161 161 161 PHE PHE A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 ASP 163 163 163 ASP ASP A . n A 1 164 GLN 164 164 164 GLN GLN A . n A 1 165 PHE 165 165 165 PHE PHE A . n A 1 166 LEU 166 166 166 LEU LEU A . n A 1 167 GLN 167 167 167 GLN GLN A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 THR 170 170 170 THR THR A . n A 1 171 ARG 171 171 171 ARG ARG A . n A 1 172 LEU 172 172 172 LEU LEU A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 THR 175 175 175 THR THR A . n A 1 176 ASN 176 176 176 ASN ASN A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TYR 178 178 178 TYR TYR A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLY 181 181 181 GLY GLY A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 HIS 183 183 183 HIS HIS A . n A 1 184 VAL 184 184 184 VAL VAL A . n A 1 185 HIS 185 185 185 HIS HIS A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 GLN 187 187 187 GLN GLN A . n A 1 188 TYR 188 188 188 TYR TYR A . n A 1 189 ARG 189 189 189 ARG ARG A . n A 1 190 HIS 190 190 190 HIS HIS A . n A 1 191 ASP 191 191 191 ASP ASP A . n A 1 192 MET 192 192 192 MET MET A . n A 1 193 ASN 193 193 193 ASN ASN A . n A 1 194 TRP 194 194 194 TRP TRP A . n A 1 195 LYS 195 195 195 LYS LYS A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 TRP 197 197 197 TRP TRP A . n A 1 198 PRO 198 198 198 PRO PRO A . n A 1 199 ILE 199 199 199 ILE ILE A . n A 1 200 PHE 200 200 200 PHE PHE A . n A 1 201 ASN 201 201 201 ASN ASN A . n A 1 202 ARG 202 202 202 ARG ARG A . n A 1 203 ASP 203 203 203 ASP ASP A . n A 1 204 THR 204 204 204 THR THR A . n A 1 205 THR 205 205 205 THR THR A . n A 1 206 PRO 206 206 206 PRO PRO A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 GLY 208 208 208 GLY GLY A . n A 1 209 ASN 209 209 209 ASN ASN A . n A 1 210 GLY 210 210 210 GLY GLY A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 ASN 212 212 212 ASN ASN A . n A 1 213 LEU 213 213 213 LEU LEU A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 GLY 215 215 215 GLY GLY A . n A 1 216 ALA 216 216 216 ALA ALA A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 PHE 219 219 219 PHE PHE A . n A 1 220 PHE 220 220 220 PHE PHE A . n A 1 221 LEU 221 221 221 LEU LEU A . n A 1 222 CYS 222 222 222 CYS CYS A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 GLU 224 224 224 GLU GLU A . n A 1 225 ASP 225 225 225 ASP ASP A . n A 1 226 ALA 226 226 226 ALA ALA A . n A 1 227 SER 227 227 227 SER SER A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 PHE 231 231 231 PHE PHE A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 PHE 234 234 234 PHE PHE A . n A 1 235 LEU 235 235 235 LEU LEU A . n A 1 236 MET 236 236 236 MET MET A . n A 1 237 ASN 237 237 237 ASN ASN A . n A 1 238 SER 238 238 238 SER SER A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 ALA 240 240 240 ALA ALA A . n A 1 241 MET 241 241 241 MET MET A . n A 1 242 GLU 242 242 242 GLU GLU A . n A 1 243 VAL 243 243 243 VAL VAL A . n A 1 244 VAL 244 244 244 VAL VAL A . n A 1 245 LEU 245 245 245 LEU LEU A . n A 1 246 GLN 246 246 246 GLN GLN A . n A 1 247 PRO 247 247 247 PRO PRO A . n A 1 248 ALA 248 248 248 ALA ALA A . n A 1 249 PRO 249 249 249 PRO PRO A . n A 1 250 ALA 250 250 250 ALA ALA A . n A 1 251 ILE 251 251 251 ILE ILE A . n A 1 252 THR 252 252 252 THR THR A . n A 1 253 TYR 253 253 253 TYR TYR A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 THR 255 255 255 THR THR A . n A 1 256 ILE 256 256 256 ILE ILE A . n A 1 257 GLY 257 257 257 GLY GLY A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 ILE 259 259 259 ILE ILE A . n A 1 260 LEU 260 260 260 LEU LEU A . n A 1 261 ASP 261 261 261 ASP ASP A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 TYR 263 263 263 TYR TYR A . n A 1 264 VAL 264 264 264 VAL VAL A . n A 1 265 PHE 265 265 265 PHE PHE A . n A 1 266 LEU 266 266 266 LEU LEU A . n A 1 267 GLY 267 267 267 GLY GLY A . n A 1 268 ASN 268 268 268 ASN ASN A . n A 1 269 THR 269 269 269 THR THR A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 GLN 272 272 272 GLN GLN A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 GLN 275 275 275 GLN GLN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 TYR 277 277 277 TYR TYR A . n A 1 278 LEU 278 278 278 LEU LEU A . n A 1 279 GLU 279 279 279 GLU GLU A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 ILE 281 281 281 ILE ILE A . n A 1 282 GLY 282 282 282 GLY GLY A . n A 1 283 ARG 283 283 283 ARG ARG A . n A 1 284 PRO 284 284 284 PRO PRO A . n A 1 285 ALA 285 285 285 ALA ALA A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 SER 288 288 288 SER SER A . n A 1 289 TYR 289 289 289 TYR TYR A . n A 1 290 TRP 290 290 290 TRP TRP A . n A 1 291 ALA 291 291 291 ALA ALA A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 PHE 294 294 294 PHE PHE A . n A 1 295 HIS 295 295 295 HIS HIS A . n A 1 296 LEU 296 296 296 LEU LEU A . n A 1 297 SER 297 297 297 SER SER A . n A 1 298 ARG 298 298 298 ARG ARG A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 GLU 300 300 300 GLU GLU A . n A 1 301 TYR 301 301 301 TYR TYR A . n A 1 302 GLY 302 302 302 GLY GLY A . n A 1 303 THR 303 303 303 THR THR A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 ASP 305 305 305 ASP ASP A . n A 1 306 ASN 306 306 306 ASN ASN A . n A 1 307 MET 307 307 307 MET MET A . n A 1 308 ARG 308 308 308 ARG ARG A . n A 1 309 GLU 309 309 309 GLU GLU A . n A 1 310 VAL 310 310 310 VAL VAL A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 GLU 312 312 312 GLU GLU A . n A 1 313 ARG 313 313 313 ARG ARG A . n A 1 314 ASN 314 314 314 ASN ASN A . n A 1 315 ARG 315 315 315 ARG ARG A . n A 1 316 ALA 316 316 316 ALA ALA A . n A 1 317 ALA 317 317 317 ALA ALA A . n A 1 318 GLN 318 318 318 GLN GLN A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 PRO 320 320 320 PRO PRO A . n A 1 321 TYR 321 321 321 TYR TYR A . n A 1 322 ASP 322 322 322 ASP ASP A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 GLN 324 324 324 GLN GLN A . n A 1 325 HIS 325 325 325 HIS HIS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 ASP 327 327 327 ASP ASP A . n A 1 328 ILE 328 328 328 ILE ILE A . n A 1 329 ASP 329 329 329 ASP ASP A . n A 1 330 TYR 330 330 330 TYR TYR A . n A 1 331 MET 331 331 331 MET MET A . n A 1 332 ASP 332 332 332 ASP ASP A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 ARG 334 334 334 ARG ARG A . n A 1 335 ARG 335 335 335 ARG ARG A . n A 1 336 ASP 336 336 336 ASP ASP A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 THR 338 338 338 THR THR A . n A 1 339 TYR 339 339 339 TYR TYR A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 SER 341 341 341 SER SER A . n A 1 342 VAL 342 342 342 VAL VAL A . n A 1 343 ASP 343 343 343 ASP ASP A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLY 346 346 346 GLY GLY A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 PRO 348 348 348 PRO PRO A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 VAL 351 351 351 VAL VAL A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 GLU 353 353 353 GLU GLU A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 HIS 355 355 355 HIS HIS A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 ASN 357 357 357 ASN ASN A . n A 1 358 GLY 358 358 358 GLY GLY A . n A 1 359 GLN 359 359 359 GLN GLN A . n A 1 360 LYS 360 360 360 LYS LYS A . n A 1 361 LEU 361 361 361 LEU LEU A . n A 1 362 VAL 362 362 362 VAL VAL A . n A 1 363 ILE 363 363 363 ILE ILE A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 VAL 365 365 365 VAL VAL A . n A 1 366 ASP 366 366 366 ASP ASP A . n A 1 367 PRO 367 367 367 PRO PRO A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 SER 370 370 370 SER SER A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 ASN 372 372 372 ASN ASN A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 SER 375 375 375 SER SER A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 LYS 377 377 377 LYS LYS A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 TYR 379 379 379 TYR TYR A . n A 1 380 GLY 380 380 380 GLY GLY A . n A 1 381 PRO 381 381 381 PRO PRO A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 ASP 383 383 383 ASP ASP A . n A 1 384 ARG 384 384 384 ARG ARG A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 SER 386 386 386 SER SER A . n A 1 387 ASP 387 387 387 ASP ASP A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 LYS 389 389 389 LYS LYS A . n A 1 390 ILE 390 390 390 ILE ILE A . n A 1 391 TRP 391 391 391 TRP TRP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 ASN 393 393 393 ASN ASN A . n A 1 394 SER 394 394 394 SER SER A . n A 1 395 SER 395 395 395 SER SER A . n A 1 396 ASP 396 396 396 ASP ASP A . n A 1 397 GLY 397 397 397 GLY GLY A . n A 1 398 VAL 398 398 398 VAL VAL A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 PRO 400 400 400 PRO PRO A . n A 1 401 LEU 401 401 401 LEU LEU A . n A 1 402 ILE 402 402 402 ILE ILE A . n A 1 403 GLY 403 403 403 GLY GLY A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 VAL 405 405 405 VAL VAL A . n A 1 406 TRP 406 406 406 TRP TRP A . n A 1 407 PRO 407 407 407 PRO PRO A . n A 1 408 GLY 408 408 408 GLY GLY A . n A 1 409 GLN 409 409 409 GLN GLN A . n A 1 410 THR 410 410 410 THR THR A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 PHE 412 412 412 PHE PHE A . n A 1 413 PRO 413 413 413 PRO PRO A . n A 1 414 ASP 414 414 414 ASP ASP A . n A 1 415 TYR 415 415 415 TYR TYR A . n A 1 416 THR 416 416 416 THR THR A . n A 1 417 ASN 417 417 417 ASN ASN A . n A 1 418 PRO 418 418 418 PRO PRO A . n A 1 419 ASN 419 419 419 ASN ASN A . n A 1 420 CYS 420 420 420 CYS CYS A . n A 1 421 ALA 421 421 421 ALA ALA A . n A 1 422 VAL 422 422 422 VAL VAL A . n A 1 423 TRP 423 423 423 TRP TRP A . n A 1 424 TRP 424 424 424 TRP TRP A . n A 1 425 THR 425 425 425 THR THR A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 GLU 427 427 427 GLU GLU A . n A 1 428 PHE 428 428 428 PHE PHE A . n A 1 429 GLU 429 429 429 GLU GLU A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 PHE 431 431 431 PHE PHE A . n A 1 432 HIS 432 432 432 HIS HIS A . n A 1 433 ASN 433 433 433 ASN ASN A . n A 1 434 GLN 434 434 434 GLN GLN A . n A 1 435 VAL 435 435 435 VAL VAL A . n A 1 436 GLU 436 436 436 GLU GLU A . n A 1 437 PHE 437 437 437 PHE PHE A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 ILE 440 440 440 ILE ILE A . n A 1 441 TRP 441 441 441 TRP TRP A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 MET 444 444 444 MET MET A . n A 1 445 ASN 445 445 445 ASN ASN A . n A 1 446 GLU 446 446 446 GLU GLU A . n A 1 447 VAL 447 447 447 VAL VAL A . n A 1 448 SER 448 448 448 SER SER A . n A 1 449 ASN 449 449 449 ASN ASN A . n A 1 450 PHE 450 450 450 PHE PHE A . n A 1 451 VAL 451 451 451 VAL VAL A . n A 1 452 ASP 452 452 452 ASP ASP A . n A 1 453 GLY 453 453 453 GLY GLY A . n A 1 454 SER 454 454 454 SER SER A . n A 1 455 VAL 455 455 455 VAL VAL A . n A 1 456 SER 456 456 456 SER SER A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 CYS 458 458 458 CYS CYS A . n A 1 459 SER 459 459 459 SER SER A . n A 1 460 THR 460 460 460 THR THR A . n A 1 461 ASN 461 461 461 ASN ASN A . n A 1 462 ASN 462 462 462 ASN ASN A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 ASN 464 464 464 ASN ASN A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 PRO 466 466 466 PRO PRO A . n A 1 467 PRO 467 467 467 PRO PRO A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 THR 469 469 469 THR THR A . n A 1 470 PRO 470 470 470 PRO PRO A . n A 1 471 ARG 471 471 471 ARG ARG A . n A 1 472 ILE 472 472 472 ILE ILE A . n A 1 473 LEU 473 473 473 LEU LEU A . n A 1 474 ASP 474 474 474 ASP ASP A . n A 1 475 GLY 475 475 475 GLY GLY A . n A 1 476 TYR 476 476 476 TYR TYR A . n A 1 477 LEU 477 477 477 LEU LEU A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 CYS 479 479 479 CYS CYS A . n A 1 480 LYS 480 480 480 LYS LYS A . n A 1 481 THR 481 481 481 THR THR A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 CYS 483 483 483 CYS CYS A . n A 1 484 MET 484 484 484 MET MET A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 ALA 486 486 486 ALA ALA A . n A 1 487 VAL 487 487 487 VAL VAL A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 HIS 489 489 489 HIS HIS A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 GLY 491 491 491 GLY GLY A . n A 1 492 LYS 492 492 492 LYS LYS A . n A 1 493 GLN 493 493 493 GLN GLN A . n A 1 494 TYR 494 494 494 TYR TYR A . n A 1 495 ASP 495 495 495 ASP ASP A . n A 1 496 ILE 496 496 496 ILE ILE A . n A 1 497 HIS 497 497 497 HIS HIS A . n A 1 498 ASN 498 498 498 ASN ASN A . n A 1 499 LEU 499 499 499 LEU LEU A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 GLY 501 501 501 GLY GLY A . n A 1 502 TYR 502 502 502 TYR TYR A . n A 1 503 SER 503 503 503 SER SER A . n A 1 504 MET 504 504 504 MET MET A . n A 1 505 ALA 505 505 505 ALA ALA A . n A 1 506 VAL 506 506 506 VAL VAL A . n A 1 507 ALA 507 507 507 ALA ALA A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ALA 509 509 509 ALA ALA A . n A 1 510 GLU 510 510 510 GLU GLU A . n A 1 511 ALA 511 511 511 ALA ALA A . n A 1 512 ALA 512 512 512 ALA ALA A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 THR 514 514 514 THR THR A . n A 1 515 VAL 515 515 515 VAL VAL A . n A 1 516 PHE 516 516 516 PHE PHE A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASN 518 518 518 ASN ASN A . n A 1 519 LYS 519 519 519 LYS LYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 SER 521 521 521 SER SER A . n A 1 522 PHE 522 522 522 PHE PHE A . n A 1 523 ILE 523 523 523 ILE ILE A . n A 1 524 LEU 524 524 524 LEU LEU A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 ARG 526 526 526 ARG ARG A . n A 1 527 SER 527 527 527 SER SER A . n A 1 528 THR 528 528 528 THR THR A . n A 1 529 PHE 529 529 529 PHE PHE A . n A 1 530 ALA 530 530 530 ALA ALA A . n A 1 531 GLY 531 531 531 GLY GLY A . n A 1 532 SER 532 532 532 SER SER A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 LYS 534 534 534 LYS LYS A . n A 1 535 PHE 535 535 535 PHE PHE A . n A 1 536 ALA 536 536 536 ALA ALA A . n A 1 537 ALA 537 537 537 ALA ALA A . n A 1 538 HIS 538 538 538 HIS HIS A . n A 1 539 TRP 539 539 539 TRP TRP A . n A 1 540 LEU 540 540 540 LEU LEU A . n A 1 541 GLY 541 541 541 GLY GLY A . n A 1 542 ASP 542 542 542 ASP ASP A . n A 1 543 ASN 543 543 543 ASN ASN A . n A 1 544 THR 544 544 544 THR THR A . n A 1 545 ALA 545 545 545 ALA ALA A . n A 1 546 THR 546 546 546 THR THR A . n A 1 547 TRP 547 547 547 TRP TRP A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ASP 549 549 549 ASP ASP A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 ARG 551 551 551 ARG ARG A . n A 1 552 TRP 552 552 552 TRP TRP A . n A 1 553 SER 553 553 553 SER SER A . n A 1 554 ILE 554 554 554 ILE ILE A . n A 1 555 PRO 555 555 555 PRO PRO A . n A 1 556 GLY 556 556 556 GLY GLY A . n A 1 557 VAL 557 557 557 VAL VAL A . n A 1 558 LEU 558 558 558 LEU LEU A . n A 1 559 GLU 559 559 559 GLU GLU A . n A 1 560 PHE 560 560 560 PHE PHE A . n A 1 561 ASN 561 561 561 ASN ASN A . n A 1 562 LEU 562 562 562 LEU LEU A . n A 1 563 PHE 563 563 563 PHE PHE A . n A 1 564 GLY 564 564 564 GLY GLY A . n A 1 565 ILE 565 565 565 ILE ILE A . n A 1 566 PRO 566 566 566 PRO PRO A . n A 1 567 MET 567 567 567 MET MET A . n A 1 568 VAL 568 568 568 VAL VAL A . n A 1 569 GLY 569 569 569 GLY GLY A . n A 1 570 PRO 570 570 570 PRO PRO A . n A 1 571 ASP 571 571 571 ASP ASP A . n A 1 572 ILE 572 572 572 ILE ILE A . n A 1 573 CYS 573 573 573 CYS CYS A . n A 1 574 GLY 574 574 574 GLY GLY A . n A 1 575 PHE 575 575 575 PHE PHE A . n A 1 576 ALA 576 576 576 ALA ALA A . n A 1 577 LEU 577 577 577 LEU LEU A . n A 1 578 ASP 578 578 578 ASP ASP A . n A 1 579 THR 579 579 579 THR THR A . n A 1 580 PRO 580 580 580 PRO PRO A . n A 1 581 GLU 581 581 581 GLU GLU A . n A 1 582 GLU 582 582 582 GLU GLU A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 CYS 584 584 584 CYS CYS A . n A 1 585 ARG 585 585 585 ARG ARG A . n A 1 586 ARG 586 586 586 ARG ARG A . n A 1 587 TRP 587 587 587 TRP TRP A . n A 1 588 MET 588 588 588 MET MET A . n A 1 589 GLN 589 589 589 GLN GLN A . n A 1 590 LEU 590 590 590 LEU LEU A . n A 1 591 GLY 591 591 591 GLY GLY A . n A 1 592 ALA 592 592 592 ALA ALA A . n A 1 593 PHE 593 593 593 PHE PHE A . n A 1 594 TYR 594 594 594 TYR TYR A . n A 1 595 PRO 595 595 595 PRO PRO A . n A 1 596 PHE 596 596 596 PHE PHE A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 ARG 598 598 598 ARG ARG A . n A 1 599 ASN 599 599 599 ASN ASN A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASN 601 601 601 ASN ASN A . n A 1 602 GLY 602 602 602 GLY GLY A . n A 1 603 GLN 603 603 603 GLN GLN A . n A 1 604 GLY 604 604 604 GLY GLY A . n A 1 605 TYR 605 605 605 TYR TYR A . n A 1 606 LYS 606 606 606 LYS LYS A . n A 1 607 ASP 607 607 607 ASP ASP A . n A 1 608 GLN 608 608 608 GLN GLN A . n A 1 609 ASP 609 609 609 ASP ASP A . n A 1 610 PRO 610 610 610 PRO PRO A . n A 1 611 ALA 611 611 611 ALA ALA A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 PHE 613 613 613 PHE PHE A . n A 1 614 GLY 614 614 614 GLY GLY A . n A 1 615 ALA 615 615 615 ALA ALA A . n A 1 616 ASP 616 616 616 ASP ASP A . n A 1 617 SER 617 617 617 SER SER A . n A 1 618 LEU 618 618 618 LEU LEU A . n A 1 619 LEU 619 619 619 LEU LEU A . n A 1 620 LEU 620 620 620 LEU LEU A . n A 1 621 ASN 621 621 621 ASN ASN A . n A 1 622 SER 622 622 622 SER SER A . n A 1 623 SER 623 623 623 SER SER A . n A 1 624 ARG 624 624 624 ARG ARG A . n A 1 625 HIS 625 625 625 HIS HIS A . n A 1 626 TYR 626 626 626 TYR TYR A . n A 1 627 LEU 627 627 627 LEU LEU A . n A 1 628 ASN 628 628 628 ASN ASN A . n A 1 629 ILE 629 629 629 ILE ILE A . n A 1 630 ARG 630 630 630 ARG ARG A . n A 1 631 TYR 631 631 631 TYR TYR A . n A 1 632 THR 632 632 632 THR THR A . n A 1 633 LEU 633 633 633 LEU LEU A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 PRO 635 635 635 PRO PRO A . n A 1 636 TYR 636 636 636 TYR TYR A . n A 1 637 LEU 637 637 637 LEU LEU A . n A 1 638 TYR 638 638 638 TYR TYR A . n A 1 639 THR 639 639 639 THR THR A . n A 1 640 LEU 640 640 640 LEU LEU A . n A 1 641 PHE 641 641 641 PHE PHE A . n A 1 642 PHE 642 642 642 PHE PHE A . n A 1 643 ARG 643 643 643 ARG ARG A . n A 1 644 ALA 644 644 644 ALA ALA A . n A 1 645 HIS 645 645 645 HIS HIS A . n A 1 646 SER 646 646 646 SER SER A . n A 1 647 ARG 647 647 647 ARG ARG A . n A 1 648 GLY 648 648 648 GLY GLY A . n A 1 649 ASP 649 649 649 ASP ASP A . n A 1 650 THR 650 650 650 THR THR A . n A 1 651 VAL 651 651 651 VAL VAL A . n A 1 652 ALA 652 652 652 ALA ALA A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 PRO 654 654 654 PRO PRO A . n A 1 655 LEU 655 655 655 LEU LEU A . n A 1 656 LEU 656 656 656 LEU LEU A . n A 1 657 HIS 657 657 657 HIS HIS A . n A 1 658 GLU 658 658 658 GLU GLU A . n A 1 659 PHE 659 659 659 PHE PHE A . n A 1 660 TYR 660 660 660 TYR TYR A . n A 1 661 GLU 661 661 661 GLU GLU A . n A 1 662 ASP 662 662 662 ASP ASP A . n A 1 663 ASN 663 663 663 ASN ASN A . n A 1 664 SER 664 664 664 SER SER A . n A 1 665 THR 665 665 665 THR THR A . n A 1 666 TRP 666 666 666 TRP TRP A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 HIS 669 669 669 HIS HIS A . n A 1 670 GLN 670 670 670 GLN GLN A . n A 1 671 GLN 671 671 671 GLN GLN A . n A 1 672 PHE 672 672 672 PHE PHE A . n A 1 673 LEU 673 673 673 LEU LEU A . n A 1 674 TRP 674 674 674 TRP TRP A . n A 1 675 GLY 675 675 675 GLY GLY A . n A 1 676 PRO 676 676 676 PRO PRO A . n A 1 677 GLY 677 677 677 GLY GLY A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 LEU 679 679 679 LEU LEU A . n A 1 680 ILE 680 680 680 ILE ILE A . n A 1 681 THR 681 681 681 THR THR A . n A 1 682 PRO 682 682 682 PRO PRO A . n A 1 683 VAL 683 683 683 VAL VAL A . n A 1 684 LEU 684 684 684 LEU LEU A . n A 1 685 ASP 685 685 685 ASP ASP A . n A 1 686 GLU 686 686 686 GLU GLU A . n A 1 687 GLY 687 687 687 GLY GLY A . n A 1 688 ALA 688 688 688 ALA ALA A . n A 1 689 GLU 689 689 689 GLU GLU A . n A 1 690 LYS 690 690 690 LYS LYS A . n A 1 691 VAL 691 691 691 VAL VAL A . n A 1 692 MET 692 692 692 MET MET A . n A 1 693 ALA 693 693 693 ALA ALA A . n A 1 694 TYR 694 694 694 TYR TYR A . n A 1 695 VAL 695 695 695 VAL VAL A . n A 1 696 PRO 696 696 696 PRO PRO A . n A 1 697 ASP 697 697 697 ASP ASP A . n A 1 698 ALA 698 698 698 ALA ALA A . n A 1 699 VAL 699 699 699 VAL VAL A . n A 1 700 TRP 700 700 700 TRP TRP A . n A 1 701 TYR 701 701 701 TYR TYR A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 TYR 703 703 703 TYR TYR A . n A 1 704 GLU 704 704 704 GLU GLU A . n A 1 705 THR 705 705 705 THR THR A . n A 1 706 GLY 706 706 706 GLY GLY A . n A 1 707 SER 707 707 707 SER SER A . n A 1 708 GLN 708 708 708 GLN GLN A . n A 1 709 VAL 709 709 709 VAL VAL A . n A 1 710 ARG 710 710 710 ARG ARG A . n A 1 711 TRP 711 711 711 TRP TRP A . n A 1 712 ARG 712 712 712 ARG ARG A . n A 1 713 LYS 713 713 713 LYS LYS A . n A 1 714 GLN 714 714 714 GLN GLN A . n A 1 715 LYS 715 715 715 LYS LYS A . n A 1 716 VAL 716 716 716 VAL VAL A . n A 1 717 GLU 717 717 717 GLU GLU A . n A 1 718 MET 718 718 718 MET MET A . n A 1 719 GLU 719 719 719 GLU GLU A . n A 1 720 LEU 720 720 720 LEU LEU A . n A 1 721 PRO 721 721 721 PRO PRO A . n A 1 722 GLY 722 722 722 GLY GLY A . n A 1 723 ASP 723 723 723 ASP ASP A . n A 1 724 LYS 724 724 724 LYS LYS A . n A 1 725 ILE 725 725 725 ILE ILE A . n A 1 726 GLY 726 726 726 GLY GLY A . n A 1 727 LEU 727 727 727 LEU LEU A . n A 1 728 HIS 728 728 728 HIS HIS A . n A 1 729 LEU 729 729 729 LEU LEU A . n A 1 730 ARG 730 730 730 ARG ARG A . n A 1 731 GLY 731 731 731 GLY GLY A . n A 1 732 GLY 732 732 732 GLY GLY A . n A 1 733 TYR 733 733 733 TYR TYR A . n A 1 734 ILE 734 734 734 ILE ILE A . n A 1 735 PHE 735 735 735 PHE PHE A . n A 1 736 PRO 736 736 736 PRO PRO A . n A 1 737 THR 737 737 737 THR THR A . n A 1 738 GLN 738 738 738 GLN GLN A . n A 1 739 GLN 739 739 739 GLN GLN A . n A 1 740 PRO 740 740 740 PRO PRO A . n A 1 741 ASN 741 741 741 ASN ASN A . n A 1 742 THR 742 742 742 THR THR A . n A 1 743 THR 743 743 743 THR THR A . n A 1 744 THR 744 744 744 THR THR A . n A 1 745 LEU 745 745 745 LEU LEU A . n A 1 746 ALA 746 746 746 ALA ALA A . n A 1 747 SER 747 747 747 SER SER A . n A 1 748 ARG 748 748 748 ARG ARG A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 ASN 750 750 750 ASN ASN A . n A 1 751 PRO 751 751 751 PRO PRO A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLY 753 753 753 GLY GLY A . n A 1 754 LEU 754 754 754 LEU LEU A . n A 1 755 ILE 755 755 755 ILE ILE A . n A 1 756 ILE 756 756 756 ILE ILE A . n A 1 757 ALA 757 757 757 ALA ALA A . n A 1 758 LEU 758 758 758 LEU LEU A . n A 1 759 ASP 759 759 759 ASP ASP A . n A 1 760 GLU 760 760 760 GLU GLU A . n A 1 761 ASN 761 761 761 ASN ASN A . n A 1 762 LYS 762 762 762 LYS LYS A . n A 1 763 GLU 763 763 763 GLU GLU A . n A 1 764 ALA 764 764 764 ALA ALA A . n A 1 765 LYS 765 765 765 LYS LYS A . n A 1 766 GLY 766 766 766 GLY GLY A . n A 1 767 GLU 767 767 767 GLU GLU A . n A 1 768 LEU 768 768 768 LEU LEU A . n A 1 769 PHE 769 769 769 PHE PHE A . n A 1 770 TRP 770 770 770 TRP TRP A . n A 1 771 ASP 771 771 771 ASP ASP A . n A 1 772 ASP 772 772 772 ASP ASP A . n A 1 773 GLY 773 773 773 GLY GLY A . n A 1 774 GLU 774 774 774 GLU GLU A . n A 1 775 THR 775 775 775 THR THR A . n A 1 776 LYS 776 776 776 LYS LYS A . n A 1 777 ASP 777 777 777 ASP ASP A . n A 1 778 THR 778 778 778 THR THR A . n A 1 779 VAL 779 779 779 VAL VAL A . n A 1 780 ALA 780 780 780 ALA ALA A . n A 1 781 ASN 781 781 781 ASN ASN A . n A 1 782 LYS 782 782 782 LYS LYS A . n A 1 783 VAL 783 783 783 VAL VAL A . n A 1 784 TYR 784 784 784 TYR TYR A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 LEU 786 786 786 LEU LEU A . n A 1 787 CYS 787 787 787 CYS CYS A . n A 1 788 GLU 788 788 788 GLU GLU A . n A 1 789 PHE 789 789 789 PHE PHE A . n A 1 790 SER 790 790 790 SER SER A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 THR 792 792 792 THR THR A . n A 1 793 GLN 793 793 793 GLN GLN A . n A 1 794 ASN 794 794 794 ASN ASN A . n A 1 795 ARG 795 795 795 ARG ARG A . n A 1 796 LEU 796 796 796 LEU LEU A . n A 1 797 GLU 797 797 797 GLU GLU A . n A 1 798 VAL 798 798 798 VAL VAL A . n A 1 799 ASN 799 799 799 ASN ASN A . n A 1 800 ILE 800 800 800 ILE ILE A . n A 1 801 SER 801 801 801 SER SER A . n A 1 802 GLN 802 802 802 GLN GLN A . n A 1 803 SER 803 803 803 SER SER A . n A 1 804 THR 804 804 804 THR THR A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 LYS 806 806 806 LYS LYS A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 PRO 808 808 808 PRO PRO A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 ASN 810 810 810 ASN ASN A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 ALA 812 812 812 ALA ALA A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ASN 814 814 814 ASN ASN A . n A 1 815 GLU 815 815 815 GLU GLU A . n A 1 816 ILE 816 816 816 ILE ILE A . n A 1 817 LYS 817 817 817 LYS LYS A . n A 1 818 ILE 818 818 818 ILE ILE A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 GLY 820 820 820 GLY GLY A . n A 1 821 THR 821 821 821 THR THR A . n A 1 822 GLU 822 822 822 GLU GLU A . n A 1 823 GLU 823 823 823 GLU GLU A . n A 1 824 PRO 824 824 824 PRO PRO A . n A 1 825 SER 825 825 825 SER SER A . n A 1 826 ASN 826 826 826 ASN ASN A . n A 1 827 VAL 827 827 827 VAL VAL A . n A 1 828 THR 828 828 828 THR THR A . n A 1 829 VAL 829 829 829 VAL VAL A . n A 1 830 LYS 830 830 830 LYS LYS A . n A 1 831 HIS 831 831 831 HIS HIS A . n A 1 832 ASN 832 832 832 ASN ASN A . n A 1 833 GLY 833 833 833 GLY GLY A . n A 1 834 VAL 834 834 834 VAL VAL A . n A 1 835 PRO 835 835 835 PRO PRO A . n A 1 836 SER 836 836 836 SER SER A . n A 1 837 GLN 837 837 ? ? ? A . n A 1 838 THR 838 838 838 THR THR A . n A 1 839 SER 839 839 839 SER SER A . n A 1 840 PRO 840 840 840 PRO PRO A . n A 1 841 THR 841 841 841 THR THR A . n A 1 842 VAL 842 842 842 VAL VAL A . n A 1 843 THR 843 843 843 THR THR A . n A 1 844 TYR 844 844 844 TYR TYR A . n A 1 845 ASP 845 845 845 ASP ASP A . n A 1 846 SER 846 846 846 SER SER A . n A 1 847 ASN 847 847 847 ASN ASN A . n A 1 848 LEU 848 848 848 LEU LEU A . n A 1 849 LYS 849 849 849 LYS LYS A . n A 1 850 VAL 850 850 850 VAL VAL A . n A 1 851 ALA 851 851 851 ALA ALA A . n A 1 852 ILE 852 852 852 ILE ILE A . n A 1 853 ILE 853 853 853 ILE ILE A . n A 1 854 THR 854 854 854 THR THR A . n A 1 855 ASP 855 855 855 ASP ASP A . n A 1 856 ILE 856 856 856 ILE ILE A . n A 1 857 ASP 857 857 857 ASP ASP A . n A 1 858 LEU 858 858 858 LEU LEU A . n A 1 859 LEU 859 859 859 LEU LEU A . n A 1 860 LEU 860 860 860 LEU LEU A . n A 1 861 GLY 861 861 861 GLY GLY A . n A 1 862 GLU 862 862 862 GLU GLU A . n A 1 863 ALA 863 863 863 ALA ALA A . n A 1 864 TYR 864 864 864 TYR TYR A . n A 1 865 THR 865 865 865 THR THR A . n A 1 866 VAL 866 866 866 VAL VAL A . n A 1 867 GLU 867 867 867 GLU GLU A . n A 1 868 TRP 868 868 868 TRP TRP A . n A 1 869 ALA 869 869 869 ALA ALA A . n A 1 870 HIS 870 870 870 HIS HIS A . n A 1 871 HIS 871 871 ? ? ? A . n A 1 872 HIS 872 872 ? ? ? A . n A 1 873 HIS 873 873 ? ? ? A . n A 1 874 HIS 874 874 ? ? ? A . n A 1 875 HIS 875 875 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NR3 1 1001 1001 NR3 NR3 A . C 3 NAG 1 2001 2001 NAG NAG A . D 3 NAG 2 2002 2002 NAG NAG A . E 3 NAG 1 2003 2003 NAG NAG A . F 4 GOL 1 3001 3001 GOL GOL A . G 4 GOL 1 3002 3002 GOL GOL A . H 4 GOL 1 3003 3003 GOL GOL A . I 4 GOL 1 3004 3004 GOL GOL A . J 5 HOH 1 4002 4002 HOH HOH A . J 5 HOH 2 4003 4003 HOH HOH A . J 5 HOH 3 4004 4004 HOH HOH A . J 5 HOH 4 4005 4005 HOH HOH A . J 5 HOH 5 4006 4006 HOH HOH A . J 5 HOH 6 4007 4007 HOH HOH A . J 5 HOH 7 4008 4008 HOH HOH A . J 5 HOH 8 4009 4009 HOH HOH A . J 5 HOH 9 4010 4010 HOH HOH A . J 5 HOH 10 4011 4011 HOH HOH A . J 5 HOH 11 4012 4012 HOH HOH A . J 5 HOH 12 4014 4014 HOH HOH A . J 5 HOH 13 4015 4015 HOH HOH A . J 5 HOH 14 4016 4016 HOH HOH A . J 5 HOH 15 4017 4017 HOH HOH A . J 5 HOH 16 4018 4018 HOH HOH A . J 5 HOH 17 4019 4019 HOH HOH A . J 5 HOH 18 4020 4020 HOH HOH A . J 5 HOH 19 4021 4021 HOH HOH A . J 5 HOH 20 4022 4022 HOH HOH A . J 5 HOH 21 4023 4023 HOH HOH A . J 5 HOH 22 4024 4024 HOH HOH A . J 5 HOH 23 4025 4025 HOH HOH A . J 5 HOH 24 4026 4026 HOH HOH A . J 5 HOH 25 4027 4027 HOH HOH A . J 5 HOH 26 4028 4028 HOH HOH A . J 5 HOH 27 4029 4029 HOH HOH A . J 5 HOH 28 4030 4030 HOH HOH A . J 5 HOH 29 4031 4031 HOH HOH A . J 5 HOH 30 4032 4032 HOH HOH A . J 5 HOH 31 4033 4033 HOH HOH A . J 5 HOH 32 4034 4034 HOH HOH A . J 5 HOH 33 4035 4035 HOH HOH A . J 5 HOH 34 4036 4036 HOH HOH A . J 5 HOH 35 4037 4037 HOH HOH A . J 5 HOH 36 4038 4038 HOH HOH A . J 5 HOH 37 4039 4039 HOH HOH A . J 5 HOH 38 4040 4040 HOH HOH A . J 5 HOH 39 4041 4041 HOH HOH A . J 5 HOH 40 4042 4042 HOH HOH A . J 5 HOH 41 4043 4043 HOH HOH A . J 5 HOH 42 4044 4044 HOH HOH A . J 5 HOH 43 4045 4045 HOH HOH A . J 5 HOH 44 4046 4046 HOH HOH A . J 5 HOH 45 4047 4047 HOH HOH A . J 5 HOH 46 4048 4048 HOH HOH A . J 5 HOH 47 4049 4049 HOH HOH A . J 5 HOH 48 4050 4050 HOH HOH A . J 5 HOH 49 4051 4051 HOH HOH A . J 5 HOH 50 4052 4052 HOH HOH A . J 5 HOH 51 4053 4053 HOH HOH A . J 5 HOH 52 4054 4054 HOH HOH A . J 5 HOH 53 4055 4055 HOH HOH A . J 5 HOH 54 4056 4056 HOH HOH A . J 5 HOH 55 4057 4057 HOH HOH A . J 5 HOH 56 4058 4058 HOH HOH A . J 5 HOH 57 4059 4059 HOH HOH A . J 5 HOH 58 4060 4060 HOH HOH A . J 5 HOH 59 4061 4061 HOH HOH A . J 5 HOH 60 4062 4062 HOH HOH A . J 5 HOH 61 4063 4063 HOH HOH A . J 5 HOH 62 4065 4065 HOH HOH A . J 5 HOH 63 4066 4066 HOH HOH A . J 5 HOH 64 4067 4067 HOH HOH A . J 5 HOH 65 4068 4068 HOH HOH A . J 5 HOH 66 4069 4069 HOH HOH A . J 5 HOH 67 4070 4070 HOH HOH A . J 5 HOH 68 4072 4072 HOH HOH A . J 5 HOH 69 4073 4073 HOH HOH A . J 5 HOH 70 4074 4074 HOH HOH A . J 5 HOH 71 4075 4075 HOH HOH A . J 5 HOH 72 4076 4076 HOH HOH A . J 5 HOH 73 4077 4077 HOH HOH A . J 5 HOH 74 4078 4078 HOH HOH A . J 5 HOH 75 4079 4079 HOH HOH A . J 5 HOH 76 4081 4081 HOH HOH A . J 5 HOH 77 4082 4082 HOH HOH A . J 5 HOH 78 4083 4083 HOH HOH A . J 5 HOH 79 4084 4084 HOH HOH A . J 5 HOH 80 4085 4085 HOH HOH A . J 5 HOH 81 4086 4086 HOH HOH A . J 5 HOH 82 4087 4087 HOH HOH A . J 5 HOH 83 4088 4088 HOH HOH A . J 5 HOH 84 4089 4089 HOH HOH A . J 5 HOH 85 4090 4090 HOH HOH A . J 5 HOH 86 4091 4091 HOH HOH A . J 5 HOH 87 4092 4092 HOH HOH A . J 5 HOH 88 4093 4093 HOH HOH A . J 5 HOH 89 4094 4094 HOH HOH A . J 5 HOH 90 4095 4095 HOH HOH A . J 5 HOH 91 4096 4096 HOH HOH A . J 5 HOH 92 4097 4097 HOH HOH A . J 5 HOH 93 4098 4098 HOH HOH A . J 5 HOH 94 4099 4099 HOH HOH A . J 5 HOH 95 4100 4100 HOH HOH A . J 5 HOH 96 4101 4101 HOH HOH A . J 5 HOH 97 4102 4102 HOH HOH A . J 5 HOH 98 4103 4103 HOH HOH A . J 5 HOH 99 4104 4104 HOH HOH A . J 5 HOH 100 4105 4105 HOH HOH A . J 5 HOH 101 4106 4106 HOH HOH A . J 5 HOH 102 4109 4109 HOH HOH A . J 5 HOH 103 4110 4110 HOH HOH A . J 5 HOH 104 4111 4111 HOH HOH A . J 5 HOH 105 4112 4112 HOH HOH A . J 5 HOH 106 4113 4113 HOH HOH A . J 5 HOH 107 4114 4114 HOH HOH A . J 5 HOH 108 4115 4115 HOH HOH A . J 5 HOH 109 4116 4116 HOH HOH A . J 5 HOH 110 4117 4117 HOH HOH A . J 5 HOH 111 4118 4118 HOH HOH A . J 5 HOH 112 4119 4119 HOH HOH A . J 5 HOH 113 4120 4120 HOH HOH A . J 5 HOH 114 4121 4121 HOH HOH A . J 5 HOH 115 4123 4123 HOH HOH A . J 5 HOH 116 4124 4124 HOH HOH A . J 5 HOH 117 4125 4125 HOH HOH A . J 5 HOH 118 4126 4126 HOH HOH A . J 5 HOH 119 4127 4127 HOH HOH A . J 5 HOH 120 4128 4128 HOH HOH A . J 5 HOH 121 4129 4129 HOH HOH A . J 5 HOH 122 4130 4130 HOH HOH A . J 5 HOH 123 4131 4131 HOH HOH A . J 5 HOH 124 4132 4132 HOH HOH A . J 5 HOH 125 4133 4133 HOH HOH A . J 5 HOH 126 4134 4134 HOH HOH A . J 5 HOH 127 4135 4135 HOH HOH A . J 5 HOH 128 4136 4136 HOH HOH A . J 5 HOH 129 4137 4137 HOH HOH A . J 5 HOH 130 4139 4139 HOH HOH A . J 5 HOH 131 4141 4141 HOH HOH A . J 5 HOH 132 4143 4143 HOH HOH A . J 5 HOH 133 4144 4144 HOH HOH A . J 5 HOH 134 4145 4145 HOH HOH A . J 5 HOH 135 4146 4146 HOH HOH A . J 5 HOH 136 4147 4147 HOH HOH A . J 5 HOH 137 4149 4149 HOH HOH A . J 5 HOH 138 4150 4150 HOH HOH A . J 5 HOH 139 4151 4151 HOH HOH A . J 5 HOH 140 4152 4152 HOH HOH A . J 5 HOH 141 4153 4153 HOH HOH A . J 5 HOH 142 4154 4154 HOH HOH A . J 5 HOH 143 4155 4155 HOH HOH A . J 5 HOH 144 4156 4156 HOH HOH A . J 5 HOH 145 4157 4157 HOH HOH A . J 5 HOH 146 4158 4158 HOH HOH A . J 5 HOH 147 4159 4159 HOH HOH A . J 5 HOH 148 4160 4160 HOH HOH A . J 5 HOH 149 4161 4161 HOH HOH A . J 5 HOH 150 4162 4162 HOH HOH A . J 5 HOH 151 4163 4163 HOH HOH A . J 5 HOH 152 4164 4164 HOH HOH A . J 5 HOH 153 4165 4165 HOH HOH A . J 5 HOH 154 4166 4166 HOH HOH A . J 5 HOH 155 4167 4167 HOH HOH A . J 5 HOH 156 4168 4168 HOH HOH A . J 5 HOH 157 4169 4169 HOH HOH A . J 5 HOH 158 4171 4171 HOH HOH A . J 5 HOH 159 4172 4172 HOH HOH A . J 5 HOH 160 4173 4173 HOH HOH A . J 5 HOH 161 4174 4174 HOH HOH A . J 5 HOH 162 4175 4175 HOH HOH A . J 5 HOH 163 4176 4176 HOH HOH A . J 5 HOH 164 4177 4177 HOH HOH A . J 5 HOH 165 4178 4178 HOH HOH A . J 5 HOH 166 4179 4179 HOH HOH A . J 5 HOH 167 4180 4180 HOH HOH A . J 5 HOH 168 4181 4181 HOH HOH A . J 5 HOH 169 4182 4182 HOH HOH A . J 5 HOH 170 4183 4183 HOH HOH A . J 5 HOH 171 4184 4184 HOH HOH A . J 5 HOH 172 4185 4185 HOH HOH A . J 5 HOH 173 4186 4186 HOH HOH A . J 5 HOH 174 4188 4188 HOH HOH A . J 5 HOH 175 4189 4189 HOH HOH A . J 5 HOH 176 4194 4194 HOH HOH A . J 5 HOH 177 4195 4195 HOH HOH A . J 5 HOH 178 4196 4196 HOH HOH A . J 5 HOH 179 4197 4197 HOH HOH A . J 5 HOH 180 4198 4198 HOH HOH A . J 5 HOH 181 4199 4199 HOH HOH A . J 5 HOH 182 4200 4200 HOH HOH A . J 5 HOH 183 4201 4201 HOH HOH A . J 5 HOH 184 4202 4202 HOH HOH A . J 5 HOH 185 4203 4203 HOH HOH A . J 5 HOH 186 4204 4204 HOH HOH A . J 5 HOH 187 4205 4205 HOH HOH A . J 5 HOH 188 4206 4206 HOH HOH A . J 5 HOH 189 4207 4207 HOH HOH A . J 5 HOH 190 4208 4208 HOH HOH A . J 5 HOH 191 4209 4209 HOH HOH A . J 5 HOH 192 4210 4210 HOH HOH A . J 5 HOH 193 4212 4212 HOH HOH A . J 5 HOH 194 4213 4213 HOH HOH A . J 5 HOH 195 4214 4214 HOH HOH A . J 5 HOH 196 4215 4215 HOH HOH A . J 5 HOH 197 4216 4216 HOH HOH A . J 5 HOH 198 4217 4217 HOH HOH A . J 5 HOH 199 4218 4218 HOH HOH A . J 5 HOH 200 4219 4219 HOH HOH A . J 5 HOH 201 4220 4220 HOH HOH A . J 5 HOH 202 4221 4221 HOH HOH A . J 5 HOH 203 4222 4222 HOH HOH A . J 5 HOH 204 4223 4223 HOH HOH A . J 5 HOH 205 4224 4224 HOH HOH A . J 5 HOH 206 4225 4225 HOH HOH A . J 5 HOH 207 4226 4226 HOH HOH A . J 5 HOH 208 4227 4227 HOH HOH A . J 5 HOH 209 4228 4228 HOH HOH A . J 5 HOH 210 4229 4229 HOH HOH A . J 5 HOH 211 4230 4230 HOH HOH A . J 5 HOH 212 4231 4231 HOH HOH A . J 5 HOH 213 4232 4232 HOH HOH A . J 5 HOH 214 4233 4233 HOH HOH A . J 5 HOH 215 4234 4234 HOH HOH A . J 5 HOH 216 4235 4235 HOH HOH A . J 5 HOH 217 4236 4236 HOH HOH A . J 5 HOH 218 4237 4237 HOH HOH A . J 5 HOH 219 4238 4238 HOH HOH A . J 5 HOH 220 4240 4240 HOH HOH A . J 5 HOH 221 4241 4241 HOH HOH A . J 5 HOH 222 4242 4242 HOH HOH A . J 5 HOH 223 4243 4243 HOH HOH A . J 5 HOH 224 4244 4244 HOH HOH A . J 5 HOH 225 4245 4245 HOH HOH A . J 5 HOH 226 4246 4246 HOH HOH A . J 5 HOH 227 4247 4247 HOH HOH A . J 5 HOH 228 4248 4248 HOH HOH A . J 5 HOH 229 4249 4249 HOH HOH A . J 5 HOH 230 4250 4250 HOH HOH A . J 5 HOH 231 4251 4251 HOH HOH A . J 5 HOH 232 4253 4253 HOH HOH A . J 5 HOH 233 4254 4254 HOH HOH A . J 5 HOH 234 4255 4255 HOH HOH A . J 5 HOH 235 4256 4256 HOH HOH A . J 5 HOH 236 4257 4257 HOH HOH A . J 5 HOH 237 4258 4258 HOH HOH A . J 5 HOH 238 4259 4259 HOH HOH A . J 5 HOH 239 4260 4260 HOH HOH A . J 5 HOH 240 4261 4261 HOH HOH A . J 5 HOH 241 4262 4262 HOH HOH A . J 5 HOH 242 4263 4263 HOH HOH A . J 5 HOH 243 4264 4264 HOH HOH A . J 5 HOH 244 4265 4265 HOH HOH A . J 5 HOH 245 4266 4266 HOH HOH A . J 5 HOH 246 4267 4267 HOH HOH A . J 5 HOH 247 4268 4268 HOH HOH A . J 5 HOH 248 4269 4269 HOH HOH A . J 5 HOH 249 4270 4270 HOH HOH A . J 5 HOH 250 4271 4271 HOH HOH A . J 5 HOH 251 4272 4272 HOH HOH A . J 5 HOH 252 4273 4273 HOH HOH A . J 5 HOH 253 4274 4274 HOH HOH A . J 5 HOH 254 4275 4275 HOH HOH A . J 5 HOH 255 4276 4276 HOH HOH A . J 5 HOH 256 4277 4277 HOH HOH A . J 5 HOH 257 4278 4278 HOH HOH A . J 5 HOH 258 4279 4279 HOH HOH A . J 5 HOH 259 4280 4280 HOH HOH A . J 5 HOH 260 4281 4281 HOH HOH A . J 5 HOH 261 4282 4282 HOH HOH A . J 5 HOH 262 4284 4284 HOH HOH A . J 5 HOH 263 4285 4285 HOH HOH A . J 5 HOH 264 4286 4286 HOH HOH A . J 5 HOH 265 4287 4287 HOH HOH A . J 5 HOH 266 4288 4288 HOH HOH A . J 5 HOH 267 4289 4289 HOH HOH A . J 5 HOH 268 4290 4290 HOH HOH A . J 5 HOH 269 4291 4291 HOH HOH A . J 5 HOH 270 4292 4292 HOH HOH A . J 5 HOH 271 4293 4293 HOH HOH A . J 5 HOH 272 4294 4294 HOH HOH A . J 5 HOH 273 4295 4295 HOH HOH A . J 5 HOH 274 4296 4296 HOH HOH A . J 5 HOH 275 4297 4297 HOH HOH A . J 5 HOH 276 4298 4298 HOH HOH A . J 5 HOH 277 4299 4299 HOH HOH A . J 5 HOH 278 4300 4300 HOH HOH A . J 5 HOH 279 4301 4301 HOH HOH A . J 5 HOH 280 4302 4302 HOH HOH A . J 5 HOH 281 4303 4303 HOH HOH A . J 5 HOH 282 4304 4304 HOH HOH A . J 5 HOH 283 4305 4305 HOH HOH A . J 5 HOH 284 4306 4306 HOH HOH A . J 5 HOH 285 4307 4307 HOH HOH A . J 5 HOH 286 4308 4308 HOH HOH A . J 5 HOH 287 4309 4309 HOH HOH A . J 5 HOH 288 4310 4310 HOH HOH A . J 5 HOH 289 4311 4311 HOH HOH A . J 5 HOH 290 4312 4312 HOH HOH A . J 5 HOH 291 4313 4313 HOH HOH A . J 5 HOH 292 4314 4314 HOH HOH A . J 5 HOH 293 4315 4315 HOH HOH A . J 5 HOH 294 4316 4316 HOH HOH A . J 5 HOH 295 4317 4317 HOH HOH A . J 5 HOH 296 4318 4318 HOH HOH A . J 5 HOH 297 4319 4319 HOH HOH A . J 5 HOH 298 4320 4320 HOH HOH A . J 5 HOH 299 4321 4321 HOH HOH A . J 5 HOH 300 4322 4322 HOH HOH A . J 5 HOH 301 4323 4323 HOH HOH A . J 5 HOH 302 4324 4324 HOH HOH A . J 5 HOH 303 4325 4325 HOH HOH A . J 5 HOH 304 4327 4327 HOH HOH A . J 5 HOH 305 4329 4329 HOH HOH A . J 5 HOH 306 4330 4330 HOH HOH A . J 5 HOH 307 4331 4331 HOH HOH A . J 5 HOH 308 4332 4332 HOH HOH A . J 5 HOH 309 4333 4333 HOH HOH A . J 5 HOH 310 4334 4334 HOH HOH A . J 5 HOH 311 4337 4337 HOH HOH A . J 5 HOH 312 4338 4338 HOH HOH A . J 5 HOH 313 4339 4339 HOH HOH A . J 5 HOH 314 4340 4340 HOH HOH A . J 5 HOH 315 4341 4341 HOH HOH A . J 5 HOH 316 4342 4342 HOH HOH A . J 5 HOH 317 4343 4343 HOH HOH A . J 5 HOH 318 4345 4345 HOH HOH A . J 5 HOH 319 4346 4346 HOH HOH A . J 5 HOH 320 4347 4347 HOH HOH A . J 5 HOH 321 4348 4348 HOH HOH A . J 5 HOH 322 4349 4349 HOH HOH A . J 5 HOH 323 4350 4350 HOH HOH A . J 5 HOH 324 4352 4352 HOH HOH A . J 5 HOH 325 4353 4353 HOH HOH A . J 5 HOH 326 4354 4354 HOH HOH A . J 5 HOH 327 4355 4355 HOH HOH A . J 5 HOH 328 4356 4356 HOH HOH A . J 5 HOH 329 4357 4357 HOH HOH A . J 5 HOH 330 4358 4358 HOH HOH A . J 5 HOH 331 4359 4359 HOH HOH A . J 5 HOH 332 4360 4360 HOH HOH A . J 5 HOH 333 4361 4361 HOH HOH A . J 5 HOH 334 4362 4362 HOH HOH A . J 5 HOH 335 4363 4363 HOH HOH A . J 5 HOH 336 4364 4364 HOH HOH A . J 5 HOH 337 4365 4365 HOH HOH A . J 5 HOH 338 4366 4366 HOH HOH A . J 5 HOH 339 4367 4367 HOH HOH A . J 5 HOH 340 4368 4368 HOH HOH A . J 5 HOH 341 4369 4369 HOH HOH A . J 5 HOH 342 4371 4371 HOH HOH A . J 5 HOH 343 4372 4372 HOH HOH A . J 5 HOH 344 4373 4373 HOH HOH A . J 5 HOH 345 4374 4374 HOH HOH A . J 5 HOH 346 4375 4375 HOH HOH A . J 5 HOH 347 4376 4376 HOH HOH A . J 5 HOH 348 4377 4377 HOH HOH A . J 5 HOH 349 4378 4378 HOH HOH A . J 5 HOH 350 4379 4379 HOH HOH A . J 5 HOH 351 4380 4380 HOH HOH A . J 5 HOH 352 4381 4381 HOH HOH A . J 5 HOH 353 4382 4382 HOH HOH A . J 5 HOH 354 4383 4383 HOH HOH A . J 5 HOH 355 4384 4384 HOH HOH A . J 5 HOH 356 4385 4385 HOH HOH A . J 5 HOH 357 4386 4386 HOH HOH A . J 5 HOH 358 4387 4387 HOH HOH A . J 5 HOH 359 4388 4388 HOH HOH A . J 5 HOH 360 4390 4390 HOH HOH A . J 5 HOH 361 4391 4391 HOH HOH A . J 5 HOH 362 4392 4392 HOH HOH A . J 5 HOH 363 4393 4393 HOH HOH A . J 5 HOH 364 4394 4394 HOH HOH A . J 5 HOH 365 4395 4395 HOH HOH A . J 5 HOH 366 4396 4396 HOH HOH A . J 5 HOH 367 4397 4397 HOH HOH A . J 5 HOH 368 4398 4398 HOH HOH A . J 5 HOH 369 4399 4399 HOH HOH A . J 5 HOH 370 4401 4401 HOH HOH A . J 5 HOH 371 4402 4402 HOH HOH A . J 5 HOH 372 4404 4404 HOH HOH A . J 5 HOH 373 4405 4405 HOH HOH A . J 5 HOH 374 4406 4406 HOH HOH A . J 5 HOH 375 4407 4407 HOH HOH A . J 5 HOH 376 4408 4408 HOH HOH A . J 5 HOH 377 4409 4409 HOH HOH A . J 5 HOH 378 4410 4410 HOH HOH A . J 5 HOH 379 4411 4411 HOH HOH A . J 5 HOH 380 4412 4412 HOH HOH A . J 5 HOH 381 4413 4413 HOH HOH A . J 5 HOH 382 4414 4414 HOH HOH A . J 5 HOH 383 4415 4415 HOH HOH A . J 5 HOH 384 4416 4416 HOH HOH A . J 5 HOH 385 4417 4417 HOH HOH A . J 5 HOH 386 4418 4418 HOH HOH A . J 5 HOH 387 4419 4419 HOH HOH A . J 5 HOH 388 4420 4420 HOH HOH A . J 5 HOH 389 4421 4421 HOH HOH A . J 5 HOH 390 4422 4422 HOH HOH A . J 5 HOH 391 4423 4423 HOH HOH A . J 5 HOH 392 4424 4424 HOH HOH A . J 5 HOH 393 4425 4425 HOH HOH A . J 5 HOH 394 4426 4426 HOH HOH A . J 5 HOH 395 4427 4427 HOH HOH A . J 5 HOH 396 4428 4428 HOH HOH A . J 5 HOH 397 4430 4430 HOH HOH A . J 5 HOH 398 4431 4431 HOH HOH A . J 5 HOH 399 4432 4432 HOH HOH A . J 5 HOH 400 4433 4433 HOH HOH A . J 5 HOH 401 4434 4434 HOH HOH A . J 5 HOH 402 4435 4435 HOH HOH A . J 5 HOH 403 4436 4436 HOH HOH A . J 5 HOH 404 4437 4437 HOH HOH A . J 5 HOH 405 4438 4438 HOH HOH A . J 5 HOH 406 4439 4439 HOH HOH A . J 5 HOH 407 4440 4440 HOH HOH A . J 5 HOH 408 4441 4441 HOH HOH A . J 5 HOH 409 4442 4442 HOH HOH A . J 5 HOH 410 4443 4443 HOH HOH A . J 5 HOH 411 4444 4444 HOH HOH A . J 5 HOH 412 4445 4445 HOH HOH A . J 5 HOH 413 4446 4446 HOH HOH A . J 5 HOH 414 4447 4447 HOH HOH A . J 5 HOH 415 4448 4448 HOH HOH A . J 5 HOH 416 4449 4449 HOH HOH A . J 5 HOH 417 4450 4450 HOH HOH A . J 5 HOH 418 4451 4451 HOH HOH A . J 5 HOH 419 4452 4452 HOH HOH A . J 5 HOH 420 4453 4453 HOH HOH A . J 5 HOH 421 4454 4454 HOH HOH A . J 5 HOH 422 4455 4455 HOH HOH A . J 5 HOH 423 4456 4456 HOH HOH A . J 5 HOH 424 4457 4457 HOH HOH A . J 5 HOH 425 4458 4458 HOH HOH A . J 5 HOH 426 4459 4459 HOH HOH A . J 5 HOH 427 4460 4460 HOH HOH A . J 5 HOH 428 4463 4463 HOH HOH A . J 5 HOH 429 4464 4464 HOH HOH A . J 5 HOH 430 4465 4465 HOH HOH A . J 5 HOH 431 4466 4466 HOH HOH A . J 5 HOH 432 4467 4467 HOH HOH A . J 5 HOH 433 4468 4468 HOH HOH A . J 5 HOH 434 4469 4469 HOH HOH A . J 5 HOH 435 4470 4470 HOH HOH A . J 5 HOH 436 4471 4471 HOH HOH A . J 5 HOH 437 4472 4472 HOH HOH A . J 5 HOH 438 4473 4473 HOH HOH A . J 5 HOH 439 4474 4474 HOH HOH A . J 5 HOH 440 4475 4475 HOH HOH A . J 5 HOH 441 4476 4476 HOH HOH A . J 5 HOH 442 4477 4477 HOH HOH A . J 5 HOH 443 4478 4478 HOH HOH A . J 5 HOH 444 4479 4479 HOH HOH A . J 5 HOH 445 4480 4480 HOH HOH A . J 5 HOH 446 4481 4481 HOH HOH A . J 5 HOH 447 4482 4482 HOH HOH A . J 5 HOH 448 4484 4484 HOH HOH A . J 5 HOH 449 4485 4485 HOH HOH A . J 5 HOH 450 4486 4486 HOH HOH A . J 5 HOH 451 4487 4487 HOH HOH A . J 5 HOH 452 4488 4488 HOH HOH A . J 5 HOH 453 4489 4489 HOH HOH A . J 5 HOH 454 4490 4490 HOH HOH A . J 5 HOH 455 4491 4491 HOH HOH A . J 5 HOH 456 4493 4493 HOH HOH A . J 5 HOH 457 4494 4494 HOH HOH A . J 5 HOH 458 4495 4495 HOH HOH A . J 5 HOH 459 4496 4496 HOH HOH A . J 5 HOH 460 4497 4497 HOH HOH A . J 5 HOH 461 4498 4498 HOH HOH A . J 5 HOH 462 4499 4499 HOH HOH A . J 5 HOH 463 4500 4500 HOH HOH A . J 5 HOH 464 4501 4501 HOH HOH A . J 5 HOH 465 4502 4502 HOH HOH A . J 5 HOH 466 4503 4503 HOH HOH A . J 5 HOH 467 4504 4504 HOH HOH A . J 5 HOH 468 4505 4505 HOH HOH A . J 5 HOH 469 4506 4506 HOH HOH A . J 5 HOH 470 4507 4507 HOH HOH A . J 5 HOH 471 4508 4508 HOH HOH A . J 5 HOH 472 4509 4509 HOH HOH A . J 5 HOH 473 4510 4510 HOH HOH A . J 5 HOH 474 4511 4511 HOH HOH A . J 5 HOH 475 4512 4512 HOH HOH A . J 5 HOH 476 4513 4513 HOH HOH A . J 5 HOH 477 4514 4514 HOH HOH A . J 5 HOH 478 4515 4515 HOH HOH A . J 5 HOH 479 4516 4516 HOH HOH A . J 5 HOH 480 4517 4517 HOH HOH A . J 5 HOH 481 4518 4518 HOH HOH A . J 5 HOH 482 4519 4519 HOH HOH A . J 5 HOH 483 4520 4520 HOH HOH A . J 5 HOH 484 4521 4521 HOH HOH A . J 5 HOH 485 4522 4522 HOH HOH A . J 5 HOH 486 4523 4523 HOH HOH A . J 5 HOH 487 4524 4524 HOH HOH A . J 5 HOH 488 4525 4525 HOH HOH A . J 5 HOH 489 4527 4527 HOH HOH A . J 5 HOH 490 4528 4528 HOH HOH A . J 5 HOH 491 4529 4529 HOH HOH A . J 5 HOH 492 4530 4530 HOH HOH A . J 5 HOH 493 4531 4531 HOH HOH A . J 5 HOH 494 4532 4532 HOH HOH A . J 5 HOH 495 4533 4533 HOH HOH A . J 5 HOH 496 4534 4534 HOH HOH A . J 5 HOH 497 4535 4535 HOH HOH A . J 5 HOH 498 4536 4536 HOH HOH A . J 5 HOH 499 4537 4537 HOH HOH A . J 5 HOH 500 4538 4538 HOH HOH A . J 5 HOH 501 4539 4539 HOH HOH A . J 5 HOH 502 4540 4540 HOH HOH A . J 5 HOH 503 4541 4541 HOH HOH A . J 5 HOH 504 4542 4542 HOH HOH A . J 5 HOH 505 4543 4543 HOH HOH A . J 5 HOH 506 4544 4544 HOH HOH A . J 5 HOH 507 4545 4545 HOH HOH A . J 5 HOH 508 4546 4546 HOH HOH A . J 5 HOH 509 4547 4547 HOH HOH A . J 5 HOH 510 4548 4548 HOH HOH A . J 5 HOH 511 4549 4549 HOH HOH A . J 5 HOH 512 4550 4550 HOH HOH A . J 5 HOH 513 4551 4551 HOH HOH A . J 5 HOH 514 4552 4552 HOH HOH A . J 5 HOH 515 4553 4553 HOH HOH A . J 5 HOH 516 4554 4554 HOH HOH A . J 5 HOH 517 4555 4555 HOH HOH A . J 5 HOH 518 4556 4556 HOH HOH A . J 5 HOH 519 4557 4557 HOH HOH A . J 5 HOH 520 4558 4558 HOH HOH A . J 5 HOH 521 4559 4559 HOH HOH A . J 5 HOH 522 4562 4562 HOH HOH A . J 5 HOH 523 4563 4563 HOH HOH A . J 5 HOH 524 4564 4564 HOH HOH A . J 5 HOH 525 4565 4565 HOH HOH A . J 5 HOH 526 4567 4567 HOH HOH A . J 5 HOH 527 4568 4568 HOH HOH A . J 5 HOH 528 4569 4569 HOH HOH A . J 5 HOH 529 4570 4570 HOH HOH A . J 5 HOH 530 4571 4571 HOH HOH A . J 5 HOH 531 4572 4572 HOH HOH A . J 5 HOH 532 4574 4574 HOH HOH A . J 5 HOH 533 4575 4575 HOH HOH A . J 5 HOH 534 4576 4576 HOH HOH A . J 5 HOH 535 4577 4577 HOH HOH A . J 5 HOH 536 4578 4578 HOH HOH A . J 5 HOH 537 4579 4579 HOH HOH A . J 5 HOH 538 4581 4581 HOH HOH A . J 5 HOH 539 4582 4582 HOH HOH A . J 5 HOH 540 4583 4583 HOH HOH A . J 5 HOH 541 4584 4584 HOH HOH A . J 5 HOH 542 4585 4585 HOH HOH A . J 5 HOH 543 4586 4586 HOH HOH A . J 5 HOH 544 4587 4587 HOH HOH A . J 5 HOH 545 4588 4588 HOH HOH A . J 5 HOH 546 4589 4589 HOH HOH A . J 5 HOH 547 4591 4591 HOH HOH A . J 5 HOH 548 4593 4593 HOH HOH A . J 5 HOH 549 4594 4594 HOH HOH A . J 5 HOH 550 4595 4595 HOH HOH A . J 5 HOH 551 4596 4596 HOH HOH A . J 5 HOH 552 4597 4597 HOH HOH A . J 5 HOH 553 4598 4598 HOH HOH A . J 5 HOH 554 4599 4599 HOH HOH A . J 5 HOH 555 4600 4600 HOH HOH A . J 5 HOH 556 4601 4601 HOH HOH A . J 5 HOH 557 4602 4602 HOH HOH A . J 5 HOH 558 4603 4603 HOH HOH A . J 5 HOH 559 4604 4604 HOH HOH A . J 5 HOH 560 4605 4605 HOH HOH A . J 5 HOH 561 4606 4606 HOH HOH A . J 5 HOH 562 4607 4607 HOH HOH A . J 5 HOH 563 4608 4608 HOH HOH A . J 5 HOH 564 4609 4609 HOH HOH A . J 5 HOH 565 4610 4610 HOH HOH A . J 5 HOH 566 4611 4611 HOH HOH A . J 5 HOH 567 4612 4612 HOH HOH A . J 5 HOH 568 4613 4613 HOH HOH A . J 5 HOH 569 4614 4614 HOH HOH A . J 5 HOH 570 4615 4615 HOH HOH A . J 5 HOH 571 4616 4616 HOH HOH A . J 5 HOH 572 4617 4617 HOH HOH A . J 5 HOH 573 4618 4618 HOH HOH A . J 5 HOH 574 4619 4619 HOH HOH A . J 5 HOH 575 4622 4622 HOH HOH A . J 5 HOH 576 4624 4624 HOH HOH A . J 5 HOH 577 4625 4625 HOH HOH A . J 5 HOH 578 4628 4628 HOH HOH A . J 5 HOH 579 4629 4629 HOH HOH A . J 5 HOH 580 4630 4630 HOH HOH A . J 5 HOH 581 4631 4631 HOH HOH A . J 5 HOH 582 4632 4632 HOH HOH A . J 5 HOH 583 4633 4633 HOH HOH A . J 5 HOH 584 4634 4634 HOH HOH A . J 5 HOH 585 4635 4635 HOH HOH A . J 5 HOH 586 4636 4636 HOH HOH A . J 5 HOH 587 4637 4637 HOH HOH A . J 5 HOH 588 4638 4638 HOH HOH A . J 5 HOH 589 4639 4639 HOH HOH A . J 5 HOH 590 4640 4640 HOH HOH A . J 5 HOH 591 4641 4641 HOH HOH A . J 5 HOH 592 4642 4642 HOH HOH A . J 5 HOH 593 4643 4643 HOH HOH A . J 5 HOH 594 4644 4644 HOH HOH A . J 5 HOH 595 4645 4645 HOH HOH A . J 5 HOH 596 4653 4653 HOH HOH A . J 5 HOH 597 4657 4657 HOH HOH A . J 5 HOH 598 4659 4659 HOH HOH A . J 5 HOH 599 4662 4662 HOH HOH A . J 5 HOH 600 4663 4663 HOH HOH A . J 5 HOH 601 4665 4665 HOH HOH A . J 5 HOH 602 4666 4666 HOH HOH A . J 5 HOH 603 4667 4667 HOH HOH A . J 5 HOH 604 4668 4668 HOH HOH A . J 5 HOH 605 4669 4669 HOH HOH A . J 5 HOH 606 4670 4670 HOH HOH A . J 5 HOH 607 4671 4671 HOH HOH A . J 5 HOH 608 4672 4672 HOH HOH A . J 5 HOH 609 4673 4673 HOH HOH A . J 5 HOH 610 4674 4674 HOH HOH A . J 5 HOH 611 4675 4675 HOH HOH A . J 5 HOH 612 4676 4676 HOH HOH A . J 5 HOH 613 4677 4677 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 393 A ASN 393 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 741 A ASN 741 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-09 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-11-01 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 3 'Structure model' '_software.classification' 2 3 'Structure model' '_software.contact_author' 3 3 'Structure model' '_software.contact_author_email' 4 3 'Structure model' '_software.date' 5 3 'Structure model' '_software.language' 6 3 'Structure model' '_software.location' 7 3 'Structure model' '_software.name' 8 3 'Structure model' '_software.type' 9 3 'Structure model' '_software.version' # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 DENZO . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data reduction' http://www.hkl-xray.com/ ? ? 2 SCALEPACK . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data scaling' http://www.hkl-xray.com/ ? ? 3 REFMAC 5.2.0019 ? program 'Garib N. Murshudov' garib@ysbl.york.ac.uk refinement http://www.ccp4.ac.uk/dist/html/refmac5.html Fortran_77 ? 4 PDB_EXTRACT 3.005 'June 11, 2008' package PDB help@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 NE _pdbx_validate_rmsd_angle.auth_asym_id_1 A _pdbx_validate_rmsd_angle.auth_comp_id_1 ARG _pdbx_validate_rmsd_angle.auth_seq_id_1 12 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CZ _pdbx_validate_rmsd_angle.auth_asym_id_2 A _pdbx_validate_rmsd_angle.auth_comp_id_2 ARG _pdbx_validate_rmsd_angle.auth_seq_id_2 12 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 NH2 _pdbx_validate_rmsd_angle.auth_asym_id_3 A _pdbx_validate_rmsd_angle.auth_comp_id_3 ARG _pdbx_validate_rmsd_angle.auth_seq_id_3 12 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 117.27 _pdbx_validate_rmsd_angle.angle_target_value 120.30 _pdbx_validate_rmsd_angle.angle_deviation -3.03 _pdbx_validate_rmsd_angle.angle_standard_deviation 0.50 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 8 ? ? -25.15 127.42 2 1 SER A 40 ? ? 76.22 -13.55 3 1 SER A 51 ? ? -111.90 -102.45 4 1 SER A 80 ? ? -67.45 94.28 5 1 LEU A 180 ? ? 72.43 147.27 6 1 GLN A 186 ? ? 77.58 -40.23 7 1 TRP A 194 ? ? 55.02 83.42 8 1 PHE A 200 ? ? -169.47 116.28 9 1 PRO A 206 ? ? -69.45 92.72 10 1 ASN A 207 ? ? -128.05 -165.70 11 1 LEU A 213 ? ? -121.57 -147.35 12 1 GLU A 300 ? ? 70.94 67.11 13 1 TYR A 321 ? ? -166.80 97.64 14 1 VAL A 342 ? ? -98.85 -62.87 15 1 VAL A 405 ? ? -134.60 -145.08 16 1 ASP A 474 ? ? 78.54 -10.16 17 1 ASN A 518 ? ? 60.00 15.43 18 1 SER A 521 ? ? 58.09 -145.37 19 1 ILE A 565 ? ? -118.97 71.22 20 1 CYS A 573 ? ? 82.31 -16.73 21 1 LEU A 577 ? ? 87.17 155.23 22 1 VAL A 651 ? ? -106.74 -67.76 23 1 GLU A 774 ? ? -151.61 -23.09 24 1 GLN A 793 ? ? -23.14 129.57 25 1 PRO A 835 ? ? -45.82 156.59 # loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 HIS A 50 ? ? SER A 51 ? ? -148.79 2 1 THR A 792 ? ? GLN A 793 ? ? -145.94 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 1 ? A SER 1 2 1 Y 1 A ALA 2 ? A ALA 2 3 1 Y 1 A GLU 3 ? A GLU 3 4 1 Y 1 A CYS 4 ? A CYS 4 5 1 Y 1 A PRO 5 ? A PRO 5 6 1 Y 1 A VAL 6 ? A VAL 6 7 1 Y 1 A GLN 837 ? A GLN 837 8 1 Y 1 A HIS 871 ? A HIS 871 9 1 Y 1 A HIS 872 ? A HIS 872 10 1 Y 1 A HIS 873 ? A HIS 873 11 1 Y 1 A HIS 874 ? A HIS 874 12 1 Y 1 A HIS 875 ? A HIS 875 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 ;(1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; NR3 3 N-ACETYL-D-GLUCOSAMINE NAG 4 GLYCEROL GOL 5 water HOH #