data_3L4V # _entry.id 3L4V # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3L4V RCSB RCSB056835 WWPDB D_1000056835 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3L4T . unspecified PDB 3L4U . unspecified PDB 3L4W . unspecified PDB 3L4X . unspecified PDB 3L4Y . unspecified PDB 3L4Z . unspecified # _pdbx_database_status.entry_id 3L4V _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2009-12-21 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sim, L.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. ; _citation.journal_abbrev Biochemistry _citation.journal_volume 49 _citation.page_first 443 _citation.page_last 451 _citation.year 2010 _citation.journal_id_ASTM BICHAW _citation.country US _citation.journal_id_ISSN 0006-2960 _citation.journal_id_CSD 0033 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20039683 _citation.pdbx_database_id_DOI 10.1021/bi9016457 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Sim, L.' 1 primary 'Jayakanthan, K.' 2 primary 'Mohan, S.' 3 primary 'Nasi, R.' 4 primary 'Johnston, B.D.' 5 primary 'Pinto, B.M.' 6 primary 'Rose, D.R.' 7 # _cell.length_a 91.278 _cell.length_b 109.693 _cell.length_c 110.075 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3L4V _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3L4V _symmetry.Int_Tables_number 19 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Maltase-glucoamylase, intestinal' 99276.742 1 '3.2.1.20, 3.2.1.3' ? 'UNP residues 87-954' ? 2 non-polymer syn ;(1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; 424.442 1 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 4 water nat water 18.015 676 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Maltase, Alpha-glucosidase, Glucoamylase, Glucan 1,4-alpha-glucosidase' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAHHHHHH ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 ALA n 1 3 GLU n 1 4 CYS n 1 5 PRO n 1 6 VAL n 1 7 VAL n 1 8 ASN n 1 9 GLU n 1 10 LEU n 1 11 GLU n 1 12 ARG n 1 13 ILE n 1 14 ASN n 1 15 CYS n 1 16 ILE n 1 17 PRO n 1 18 ASP n 1 19 GLN n 1 20 PRO n 1 21 PRO n 1 22 THR n 1 23 LYS n 1 24 ALA n 1 25 THR n 1 26 CYS n 1 27 ASP n 1 28 GLN n 1 29 ARG n 1 30 GLY n 1 31 CYS n 1 32 CYS n 1 33 TRP n 1 34 ASN n 1 35 PRO n 1 36 GLN n 1 37 GLY n 1 38 ALA n 1 39 VAL n 1 40 SER n 1 41 VAL n 1 42 PRO n 1 43 TRP n 1 44 CYS n 1 45 TYR n 1 46 TYR n 1 47 SER n 1 48 LYS n 1 49 ASN n 1 50 HIS n 1 51 SER n 1 52 TYR n 1 53 HIS n 1 54 VAL n 1 55 GLU n 1 56 GLY n 1 57 ASN n 1 58 LEU n 1 59 VAL n 1 60 ASN n 1 61 THR n 1 62 ASN n 1 63 ALA n 1 64 GLY n 1 65 PHE n 1 66 THR n 1 67 ALA n 1 68 ARG n 1 69 LEU n 1 70 LYS n 1 71 ASN n 1 72 LEU n 1 73 PRO n 1 74 SER n 1 75 SER n 1 76 PRO n 1 77 VAL n 1 78 PHE n 1 79 GLY n 1 80 SER n 1 81 ASN n 1 82 VAL n 1 83 ASP n 1 84 ASN n 1 85 VAL n 1 86 LEU n 1 87 LEU n 1 88 THR n 1 89 ALA n 1 90 GLU n 1 91 TYR n 1 92 GLN n 1 93 THR n 1 94 SER n 1 95 ASN n 1 96 ARG n 1 97 PHE n 1 98 HIS n 1 99 PHE n 1 100 LYS n 1 101 LEU n 1 102 THR n 1 103 ASP n 1 104 GLN n 1 105 THR n 1 106 ASN n 1 107 ASN n 1 108 ARG n 1 109 PHE n 1 110 GLU n 1 111 VAL n 1 112 PRO n 1 113 HIS n 1 114 GLU n 1 115 HIS n 1 116 VAL n 1 117 GLN n 1 118 SER n 1 119 PHE n 1 120 SER n 1 121 GLY n 1 122 ASN n 1 123 ALA n 1 124 ALA n 1 125 ALA n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 TYR n 1 130 GLN n 1 131 VAL n 1 132 GLU n 1 133 ILE n 1 134 SER n 1 135 ARG n 1 136 GLN n 1 137 PRO n 1 138 PHE n 1 139 SER n 1 140 ILE n 1 141 LYS n 1 142 VAL n 1 143 THR n 1 144 ARG n 1 145 ARG n 1 146 SER n 1 147 ASN n 1 148 ASN n 1 149 ARG n 1 150 VAL n 1 151 LEU n 1 152 PHE n 1 153 ASP n 1 154 SER n 1 155 SER n 1 156 ILE n 1 157 GLY n 1 158 PRO n 1 159 LEU n 1 160 LEU n 1 161 PHE n 1 162 ALA n 1 163 ASP n 1 164 GLN n 1 165 PHE n 1 166 LEU n 1 167 GLN n 1 168 LEU n 1 169 SER n 1 170 THR n 1 171 ARG n 1 172 LEU n 1 173 PRO n 1 174 SER n 1 175 THR n 1 176 ASN n 1 177 VAL n 1 178 TYR n 1 179 GLY n 1 180 LEU n 1 181 GLY n 1 182 GLU n 1 183 HIS n 1 184 VAL n 1 185 HIS n 1 186 GLN n 1 187 GLN n 1 188 TYR n 1 189 ARG n 1 190 HIS n 1 191 ASP n 1 192 MET n 1 193 ASN n 1 194 TRP n 1 195 LYS n 1 196 THR n 1 197 TRP n 1 198 PRO n 1 199 ILE n 1 200 PHE n 1 201 ASN n 1 202 ARG n 1 203 ASP n 1 204 THR n 1 205 THR n 1 206 PRO n 1 207 ASN n 1 208 GLY n 1 209 ASN n 1 210 GLY n 1 211 THR n 1 212 ASN n 1 213 LEU n 1 214 TYR n 1 215 GLY n 1 216 ALA n 1 217 GLN n 1 218 THR n 1 219 PHE n 1 220 PHE n 1 221 LEU n 1 222 CYS n 1 223 LEU n 1 224 GLU n 1 225 ASP n 1 226 ALA n 1 227 SER n 1 228 GLY n 1 229 LEU n 1 230 SER n 1 231 PHE n 1 232 GLY n 1 233 VAL n 1 234 PHE n 1 235 LEU n 1 236 MET n 1 237 ASN n 1 238 SER n 1 239 ASN n 1 240 ALA n 1 241 MET n 1 242 GLU n 1 243 VAL n 1 244 VAL n 1 245 LEU n 1 246 GLN n 1 247 PRO n 1 248 ALA n 1 249 PRO n 1 250 ALA n 1 251 ILE n 1 252 THR n 1 253 TYR n 1 254 ARG n 1 255 THR n 1 256 ILE n 1 257 GLY n 1 258 GLY n 1 259 ILE n 1 260 LEU n 1 261 ASP n 1 262 PHE n 1 263 TYR n 1 264 VAL n 1 265 PHE n 1 266 LEU n 1 267 GLY n 1 268 ASN n 1 269 THR n 1 270 PRO n 1 271 GLU n 1 272 GLN n 1 273 VAL n 1 274 VAL n 1 275 GLN n 1 276 GLU n 1 277 TYR n 1 278 LEU n 1 279 GLU n 1 280 LEU n 1 281 ILE n 1 282 GLY n 1 283 ARG n 1 284 PRO n 1 285 ALA n 1 286 LEU n 1 287 PRO n 1 288 SER n 1 289 TYR n 1 290 TRP n 1 291 ALA n 1 292 LEU n 1 293 GLY n 1 294 PHE n 1 295 HIS n 1 296 LEU n 1 297 SER n 1 298 ARG n 1 299 TYR n 1 300 GLU n 1 301 TYR n 1 302 GLY n 1 303 THR n 1 304 LEU n 1 305 ASP n 1 306 ASN n 1 307 MET n 1 308 ARG n 1 309 GLU n 1 310 VAL n 1 311 VAL n 1 312 GLU n 1 313 ARG n 1 314 ASN n 1 315 ARG n 1 316 ALA n 1 317 ALA n 1 318 GLN n 1 319 LEU n 1 320 PRO n 1 321 TYR n 1 322 ASP n 1 323 VAL n 1 324 GLN n 1 325 HIS n 1 326 ALA n 1 327 ASP n 1 328 ILE n 1 329 ASP n 1 330 TYR n 1 331 MET n 1 332 ASP n 1 333 GLU n 1 334 ARG n 1 335 ARG n 1 336 ASP n 1 337 PHE n 1 338 THR n 1 339 TYR n 1 340 ASP n 1 341 SER n 1 342 VAL n 1 343 ASP n 1 344 PHE n 1 345 LYS n 1 346 GLY n 1 347 PHE n 1 348 PRO n 1 349 GLU n 1 350 PHE n 1 351 VAL n 1 352 ASN n 1 353 GLU n 1 354 LEU n 1 355 HIS n 1 356 ASN n 1 357 ASN n 1 358 GLY n 1 359 GLN n 1 360 LYS n 1 361 LEU n 1 362 VAL n 1 363 ILE n 1 364 ILE n 1 365 VAL n 1 366 ASP n 1 367 PRO n 1 368 ALA n 1 369 ILE n 1 370 SER n 1 371 ASN n 1 372 ASN n 1 373 SER n 1 374 SER n 1 375 SER n 1 376 SER n 1 377 LYS n 1 378 PRO n 1 379 TYR n 1 380 GLY n 1 381 PRO n 1 382 TYR n 1 383 ASP n 1 384 ARG n 1 385 GLY n 1 386 SER n 1 387 ASP n 1 388 MET n 1 389 LYS n 1 390 ILE n 1 391 TRP n 1 392 VAL n 1 393 ASN n 1 394 SER n 1 395 SER n 1 396 ASP n 1 397 GLY n 1 398 VAL n 1 399 THR n 1 400 PRO n 1 401 LEU n 1 402 ILE n 1 403 GLY n 1 404 GLU n 1 405 VAL n 1 406 TRP n 1 407 PRO n 1 408 GLY n 1 409 GLN n 1 410 THR n 1 411 VAL n 1 412 PHE n 1 413 PRO n 1 414 ASP n 1 415 TYR n 1 416 THR n 1 417 ASN n 1 418 PRO n 1 419 ASN n 1 420 CYS n 1 421 ALA n 1 422 VAL n 1 423 TRP n 1 424 TRP n 1 425 THR n 1 426 LYS n 1 427 GLU n 1 428 PHE n 1 429 GLU n 1 430 LEU n 1 431 PHE n 1 432 HIS n 1 433 ASN n 1 434 GLN n 1 435 VAL n 1 436 GLU n 1 437 PHE n 1 438 ASP n 1 439 GLY n 1 440 ILE n 1 441 TRP n 1 442 ILE n 1 443 ASP n 1 444 MET n 1 445 ASN n 1 446 GLU n 1 447 VAL n 1 448 SER n 1 449 ASN n 1 450 PHE n 1 451 VAL n 1 452 ASP n 1 453 GLY n 1 454 SER n 1 455 VAL n 1 456 SER n 1 457 GLY n 1 458 CYS n 1 459 SER n 1 460 THR n 1 461 ASN n 1 462 ASN n 1 463 LEU n 1 464 ASN n 1 465 ASN n 1 466 PRO n 1 467 PRO n 1 468 PHE n 1 469 THR n 1 470 PRO n 1 471 ARG n 1 472 ILE n 1 473 LEU n 1 474 ASP n 1 475 GLY n 1 476 TYR n 1 477 LEU n 1 478 PHE n 1 479 CYS n 1 480 LYS n 1 481 THR n 1 482 LEU n 1 483 CYS n 1 484 MET n 1 485 ASP n 1 486 ALA n 1 487 VAL n 1 488 GLN n 1 489 HIS n 1 490 TRP n 1 491 GLY n 1 492 LYS n 1 493 GLN n 1 494 TYR n 1 495 ASP n 1 496 ILE n 1 497 HIS n 1 498 ASN n 1 499 LEU n 1 500 TYR n 1 501 GLY n 1 502 TYR n 1 503 SER n 1 504 MET n 1 505 ALA n 1 506 VAL n 1 507 ALA n 1 508 THR n 1 509 ALA n 1 510 GLU n 1 511 ALA n 1 512 ALA n 1 513 LYS n 1 514 THR n 1 515 VAL n 1 516 PHE n 1 517 PRO n 1 518 ASN n 1 519 LYS n 1 520 ARG n 1 521 SER n 1 522 PHE n 1 523 ILE n 1 524 LEU n 1 525 THR n 1 526 ARG n 1 527 SER n 1 528 THR n 1 529 PHE n 1 530 ALA n 1 531 GLY n 1 532 SER n 1 533 GLY n 1 534 LYS n 1 535 PHE n 1 536 ALA n 1 537 ALA n 1 538 HIS n 1 539 TRP n 1 540 LEU n 1 541 GLY n 1 542 ASP n 1 543 ASN n 1 544 THR n 1 545 ALA n 1 546 THR n 1 547 TRP n 1 548 ASP n 1 549 ASP n 1 550 LEU n 1 551 ARG n 1 552 TRP n 1 553 SER n 1 554 ILE n 1 555 PRO n 1 556 GLY n 1 557 VAL n 1 558 LEU n 1 559 GLU n 1 560 PHE n 1 561 ASN n 1 562 LEU n 1 563 PHE n 1 564 GLY n 1 565 ILE n 1 566 PRO n 1 567 MET n 1 568 VAL n 1 569 GLY n 1 570 PRO n 1 571 ASP n 1 572 ILE n 1 573 CYS n 1 574 GLY n 1 575 PHE n 1 576 ALA n 1 577 LEU n 1 578 ASP n 1 579 THR n 1 580 PRO n 1 581 GLU n 1 582 GLU n 1 583 LEU n 1 584 CYS n 1 585 ARG n 1 586 ARG n 1 587 TRP n 1 588 MET n 1 589 GLN n 1 590 LEU n 1 591 GLY n 1 592 ALA n 1 593 PHE n 1 594 TYR n 1 595 PRO n 1 596 PHE n 1 597 SER n 1 598 ARG n 1 599 ASN n 1 600 HIS n 1 601 ASN n 1 602 GLY n 1 603 GLN n 1 604 GLY n 1 605 TYR n 1 606 LYS n 1 607 ASP n 1 608 GLN n 1 609 ASP n 1 610 PRO n 1 611 ALA n 1 612 SER n 1 613 PHE n 1 614 GLY n 1 615 ALA n 1 616 ASP n 1 617 SER n 1 618 LEU n 1 619 LEU n 1 620 LEU n 1 621 ASN n 1 622 SER n 1 623 SER n 1 624 ARG n 1 625 HIS n 1 626 TYR n 1 627 LEU n 1 628 ASN n 1 629 ILE n 1 630 ARG n 1 631 TYR n 1 632 THR n 1 633 LEU n 1 634 LEU n 1 635 PRO n 1 636 TYR n 1 637 LEU n 1 638 TYR n 1 639 THR n 1 640 LEU n 1 641 PHE n 1 642 PHE n 1 643 ARG n 1 644 ALA n 1 645 HIS n 1 646 SER n 1 647 ARG n 1 648 GLY n 1 649 ASP n 1 650 THR n 1 651 VAL n 1 652 ALA n 1 653 ARG n 1 654 PRO n 1 655 LEU n 1 656 LEU n 1 657 HIS n 1 658 GLU n 1 659 PHE n 1 660 TYR n 1 661 GLU n 1 662 ASP n 1 663 ASN n 1 664 SER n 1 665 THR n 1 666 TRP n 1 667 ASP n 1 668 VAL n 1 669 HIS n 1 670 GLN n 1 671 GLN n 1 672 PHE n 1 673 LEU n 1 674 TRP n 1 675 GLY n 1 676 PRO n 1 677 GLY n 1 678 LEU n 1 679 LEU n 1 680 ILE n 1 681 THR n 1 682 PRO n 1 683 VAL n 1 684 LEU n 1 685 ASP n 1 686 GLU n 1 687 GLY n 1 688 ALA n 1 689 GLU n 1 690 LYS n 1 691 VAL n 1 692 MET n 1 693 ALA n 1 694 TYR n 1 695 VAL n 1 696 PRO n 1 697 ASP n 1 698 ALA n 1 699 VAL n 1 700 TRP n 1 701 TYR n 1 702 ASP n 1 703 TYR n 1 704 GLU n 1 705 THR n 1 706 GLY n 1 707 SER n 1 708 GLN n 1 709 VAL n 1 710 ARG n 1 711 TRP n 1 712 ARG n 1 713 LYS n 1 714 GLN n 1 715 LYS n 1 716 VAL n 1 717 GLU n 1 718 MET n 1 719 GLU n 1 720 LEU n 1 721 PRO n 1 722 GLY n 1 723 ASP n 1 724 LYS n 1 725 ILE n 1 726 GLY n 1 727 LEU n 1 728 HIS n 1 729 LEU n 1 730 ARG n 1 731 GLY n 1 732 GLY n 1 733 TYR n 1 734 ILE n 1 735 PHE n 1 736 PRO n 1 737 THR n 1 738 GLN n 1 739 GLN n 1 740 PRO n 1 741 ASN n 1 742 THR n 1 743 THR n 1 744 THR n 1 745 LEU n 1 746 ALA n 1 747 SER n 1 748 ARG n 1 749 LYS n 1 750 ASN n 1 751 PRO n 1 752 LEU n 1 753 GLY n 1 754 LEU n 1 755 ILE n 1 756 ILE n 1 757 ALA n 1 758 LEU n 1 759 ASP n 1 760 GLU n 1 761 ASN n 1 762 LYS n 1 763 GLU n 1 764 ALA n 1 765 LYS n 1 766 GLY n 1 767 GLU n 1 768 LEU n 1 769 PHE n 1 770 TRP n 1 771 ASP n 1 772 ASP n 1 773 GLY n 1 774 GLU n 1 775 THR n 1 776 LYS n 1 777 ASP n 1 778 THR n 1 779 VAL n 1 780 ALA n 1 781 ASN n 1 782 LYS n 1 783 VAL n 1 784 TYR n 1 785 LEU n 1 786 LEU n 1 787 CYS n 1 788 GLU n 1 789 PHE n 1 790 SER n 1 791 VAL n 1 792 THR n 1 793 GLN n 1 794 ASN n 1 795 ARG n 1 796 LEU n 1 797 GLU n 1 798 VAL n 1 799 ASN n 1 800 ILE n 1 801 SER n 1 802 GLN n 1 803 SER n 1 804 THR n 1 805 TYR n 1 806 LYS n 1 807 ASP n 1 808 PRO n 1 809 ASN n 1 810 ASN n 1 811 LEU n 1 812 ALA n 1 813 PHE n 1 814 ASN n 1 815 GLU n 1 816 ILE n 1 817 LYS n 1 818 ILE n 1 819 LEU n 1 820 GLY n 1 821 THR n 1 822 GLU n 1 823 GLU n 1 824 PRO n 1 825 SER n 1 826 ASN n 1 827 VAL n 1 828 THR n 1 829 VAL n 1 830 LYS n 1 831 HIS n 1 832 ASN n 1 833 GLY n 1 834 VAL n 1 835 PRO n 1 836 SER n 1 837 GLN n 1 838 THR n 1 839 SER n 1 840 PRO n 1 841 THR n 1 842 VAL n 1 843 THR n 1 844 TYR n 1 845 ASP n 1 846 SER n 1 847 ASN n 1 848 LEU n 1 849 LYS n 1 850 VAL n 1 851 ALA n 1 852 ILE n 1 853 ILE n 1 854 THR n 1 855 ASP n 1 856 ILE n 1 857 ASP n 1 858 LEU n 1 859 LEU n 1 860 LEU n 1 861 GLY n 1 862 GLU n 1 863 ALA n 1 864 TYR n 1 865 THR n 1 866 VAL n 1 867 GLU n 1 868 TRP n 1 869 ALA n 1 870 HIS n 1 871 HIS n 1 872 HIS n 1 873 HIS n 1 874 HIS n 1 875 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'MGA, MGAM, MGAML' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMT-BiP-V5-His _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MGA_HUMAN _struct_ref.pdbx_db_accession O43451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW ; _struct_ref.pdbx_align_begin 87 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3L4V _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 868 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O43451 _struct_ref_seq.db_align_beg 87 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 954 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 868 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3L4V ASP A 772 ? UNP O43451 ASN 858 VARIANT 772 1 1 3L4V ALA A 869 ? UNP O43451 ? ? 'EXPRESSION TAG' 869 2 1 3L4V HIS A 870 ? UNP O43451 ? ? 'EXPRESSION TAG' 870 3 1 3L4V HIS A 871 ? UNP O43451 ? ? 'EXPRESSION TAG' 871 4 1 3L4V HIS A 872 ? UNP O43451 ? ? 'EXPRESSION TAG' 872 5 1 3L4V HIS A 873 ? UNP O43451 ? ? 'EXPRESSION TAG' 873 6 1 3L4V HIS A 874 ? UNP O43451 ? ? 'EXPRESSION TAG' 874 7 1 3L4V HIS A 875 ? UNP O43451 ? ? 'EXPRESSION TAG' 875 8 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 KTL non-polymer . ;(1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; ? 'C12 H24 O12 S2' 424.442 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3L4V _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.78 _exptl_crystal.density_percent_sol 55.68 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '20% PEG 3350, 0.2M sodium sulfate, pH 6.5, vapor diffusion, hanging drop, temperature 293K' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2009-04-19 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9175 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9175 # _reflns.entry_id 3L4V _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 20.000 _reflns.d_resolution_high 2.100 _reflns.number_obs 65399 _reflns.number_all ? _reflns.percent_possible_obs 99.900 _reflns.pdbx_Rmerge_I_obs 0.122 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 9.200 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 7.300 _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # loop_ _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.percent_possible_all _reflns_shell.Rmerge_I_obs _reflns_shell.pdbx_Rsym_value _reflns_shell.meanI_over_sigI_obs _reflns_shell.pdbx_redundancy _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_ordinal 2.10 2.14 100.00 0.515 ? ? 7.40 ? 1 2.14 2.17 100.00 0.448 ? ? 7.40 ? 2 2.17 2.22 100.00 0.425 ? ? 7.40 ? 3 2.22 2.26 100.00 0.324 ? ? 7.40 ? 4 2.26 2.31 100.00 0.381 ? ? 7.40 ? 5 2.31 2.36 100.00 0.329 ? ? 7.40 ? 6 2.36 2.42 100.00 0.283 ? ? 7.40 ? 7 2.42 2.49 100.00 0.249 ? ? 7.40 ? 8 2.49 2.56 100.00 0.233 ? ? 7.40 ? 9 2.56 2.64 100.00 0.206 ? ? 7.40 ? 10 2.64 2.74 100.00 0.179 ? ? 7.40 ? 11 2.74 2.85 100.00 0.158 ? ? 7.40 ? 12 2.85 2.98 100.00 0.136 ? ? 7.40 ? 13 2.98 3.13 100.00 0.119 ? ? 7.40 ? 14 3.13 3.33 100.00 0.101 ? ? 7.40 ? 15 3.33 3.59 100.00 0.091 ? ? 7.40 ? 16 3.59 3.94 100.00 0.081 ? ? 7.30 ? 17 3.94 4.51 99.80 0.075 ? ? 7.30 ? 18 4.51 5.66 99.90 0.073 ? ? 7.20 ? 19 5.66 20.00 98.70 0.091 ? ? 6.60 ? 20 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 3L4V _refine.ls_number_reflns_obs 61109 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F . _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.81 _refine.ls_d_res_high 2.10 _refine.ls_percent_reflns_obs 99.00 _refine.ls_R_factor_obs 0.18456 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.18209 _refine.ls_R_factor_R_free 0.23160 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 3266 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min 0.50 _refine.occupancy_max 1.00 _refine.correlation_coeff_Fo_to_Fc 0.954 _refine.correlation_coeff_Fo_to_Fc_free 0.926 _refine.B_iso_mean 26.477 _refine.aniso_B[1][1] 0.00 _refine.aniso_B[2][2] 0.00 _refine.aniso_B[3][3] 0.00 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.198 _refine.pdbx_overall_ESU_R_Free 0.177 _refine.overall_SU_ML 0.122 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 4.654 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6986 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 96 _refine_hist.number_atoms_solvent 676 _refine_hist.number_atoms_total 7758 _refine_hist.d_res_high 2.10 _refine_hist.d_res_low 19.81 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.015 0.022 ? 7300 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.583 1.949 ? 9983 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.774 5.000 ? 885 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 36.678 24.424 ? 373 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 14.762 15.000 ? 1115 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 14.552 15.000 ? 39 'X-RAY DIFFRACTION' ? r_chiral_restr 0.116 0.200 ? 1079 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.006 0.020 ? 5720 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined 0.206 0.200 ? 3349 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.312 0.200 ? 4901 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.161 0.200 ? 688 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.282 0.200 ? 50 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.230 0.200 ? 12 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.915 1.500 ? 4472 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.516 2.000 ? 7058 'X-RAY DIFFRACTION' ? r_scbond_it 2.418 3.000 ? 3292 'X-RAY DIFFRACTION' ? r_scangle_it 3.693 4.500 ? 2915 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.100 _refine_ls_shell.d_res_low 2.154 _refine_ls_shell.number_reflns_R_work 4398 _refine_ls_shell.R_factor_R_work 0.231 _refine_ls_shell.percent_reflns_obs 98.74 _refine_ls_shell.R_factor_R_free 0.303 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 240 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 3L4V _struct.title 'Crystal complex of N-terminal Human Maltase-Glucoamylase with kotalanol' _struct.pdbx_descriptor 'Maltase-glucoamylase, intestinal (E.C.3.2.1.20, 3.2.1.3)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3L4V _struct_keywords.text ;Glycoside Hydrolase Family 31, Cell membrane, Disulfide bond, Glycoprotein, Glycosidase, Hydrolase, Membrane, Multifunctional enzyme, Polymorphism, Signal-anchor, Sulfation, Transmembrane ; _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 4 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 8 ? ARG A 12 ? ASN A 8 ARG A 12 5 ? 5 HELX_P HELX_P2 2 THR A 22 ? GLY A 30 ? THR A 22 GLY A 30 1 ? 9 HELX_P HELX_P3 3 SER A 155 ? GLY A 157 ? SER A 155 GLY A 157 5 ? 3 HELX_P HELX_P4 4 THR A 269 ? GLY A 282 ? THR A 269 GLY A 282 1 ? 14 HELX_P HELX_P5 5 SER A 288 ? GLY A 293 ? SER A 288 GLY A 293 5 ? 6 HELX_P HELX_P6 6 THR A 303 ? ALA A 317 ? THR A 303 ALA A 317 1 ? 15 HELX_P HELX_P7 7 ASP A 327 ? MET A 331 ? ASP A 327 MET A 331 5 ? 5 HELX_P HELX_P8 8 GLY A 346 ? ASN A 357 ? GLY A 346 ASN A 357 1 ? 12 HELX_P HELX_P9 9 TYR A 379 ? LYS A 389 ? TYR A 379 LYS A 389 1 ? 11 HELX_P HELX_P10 10 ASN A 417 ? ASN A 433 ? ASN A 417 ASN A 433 1 ? 17 HELX_P HELX_P11 11 GLN A 493 ? HIS A 497 ? GLN A 493 HIS A 497 1 ? 5 HELX_P HELX_P12 12 LEU A 499 ? PHE A 516 ? LEU A 499 PHE A 516 1 ? 18 HELX_P HELX_P13 13 GLY A 531 ? PHE A 535 ? GLY A 531 PHE A 535 5 ? 5 HELX_P HELX_P14 14 THR A 546 ? PHE A 563 ? THR A 546 PHE A 563 1 ? 18 HELX_P HELX_P15 15 PRO A 580 ? ALA A 592 ? PRO A 580 ALA A 592 1 ? 13 HELX_P HELX_P16 16 ASP A 609 ? GLY A 614 ? ASP A 609 GLY A 614 5 ? 6 HELX_P HELX_P17 17 SER A 617 ? LEU A 633 ? SER A 617 LEU A 633 1 ? 17 HELX_P HELX_P18 18 LEU A 633 ? ARG A 647 ? LEU A 633 ARG A 647 1 ? 15 HELX_P HELX_P19 19 PRO A 654 ? PHE A 659 ? PRO A 654 PHE A 659 1 ? 6 HELX_P HELX_P20 20 ASP A 662 ? TRP A 666 ? ASP A 662 TRP A 666 5 ? 5 HELX_P HELX_P21 21 THR A 743 ? ARG A 748 ? THR A 743 ARG A 748 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 31 SG ? ? A CYS 15 A CYS 31 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 458 SG ? ? ? 1_555 A CYS 483 SG ? ? A CYS 458 A CYS 483 1_555 ? ? ? ? ? ? ? 2.874 ? disulf3 disulf ? ? A CYS 573 SG ? ? ? 1_555 A CYS 584 SG ? ? A CYS 573 A CYS 584 1_555 ? ? ? ? ? ? ? 2.052 ? covale1 covale ? ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? A NAG 2003 A NAG 2004 1_555 ? ? ? ? ? ? ? 1.433 ? covale2 covale ? ? A ASN 393 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 393 A NAG 2003 1_555 ? ? ? ? ? ? ? 1.449 ? covale3 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 2001 A NAG 2002 1_555 ? ? ? ? ? ? ? 1.451 ? covale4 covale ? ? A ASN 209 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 209 A NAG 2005 1_555 ? ? ? ? ? ? ? 1.456 ? covale5 covale ? ? A ASN 741 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 741 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.460 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLN 136 A . ? GLN 136 A PRO 137 A ? PRO 137 A 1 1.11 2 GLY 181 A . ? GLY 181 A GLU 182 A ? GLU 182 A 1 2.07 3 ALA 248 A . ? ALA 248 A PRO 249 A ? PRO 249 A 1 -5.85 4 GLU 446 A . ? GLU 446 A VAL 447 A ? VAL 447 A 1 6.26 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 8 ? C ? 3 ? D ? 5 ? E ? 9 ? F ? 3 ? G ? 2 ? H ? 5 ? I ? 2 ? J ? 10 ? K ? 9 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? parallel E 5 6 ? parallel E 6 7 ? parallel E 7 8 ? parallel E 8 9 ? parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? parallel J 6 7 ? anti-parallel J 7 8 ? parallel J 8 9 ? anti-parallel J 9 10 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel K 5 6 ? parallel K 6 7 ? anti-parallel K 7 8 ? parallel K 8 9 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 CYS A 32 ? TRP A 33 ? CYS A 32 TRP A 33 A 2 CYS A 44 ? TYR A 45 ? CYS A 44 TYR A 45 B 1 SER A 51 ? ASN A 60 ? SER A 51 ASN A 60 B 2 GLY A 64 ? LEU A 72 ? GLY A 64 LEU A 72 B 3 ASN A 84 ? THR A 93 ? ASN A 84 THR A 93 B 4 ARG A 96 ? ASP A 103 ? ARG A 96 ASP A 103 B 5 LEU A 260 ? GLY A 267 ? LEU A 260 GLY A 267 B 6 SER A 230 ? LEU A 235 ? SER A 230 LEU A 235 B 7 GLN A 217 ? LEU A 223 ? GLN A 217 LEU A 223 B 8 VAL A 177 ? GLY A 181 ? VAL A 177 GLY A 181 C 1 TYR A 129 ? SER A 134 ? TYR A 129 SER A 134 C 2 SER A 139 ? ARG A 144 ? SER A 139 ARG A 144 C 3 VAL A 150 ? ASP A 153 ? VAL A 150 ASP A 153 D 1 LEU A 160 ? ALA A 162 ? LEU A 160 ALA A 162 D 2 PHE A 165 ? ARG A 171 ? PHE A 165 ARG A 171 D 3 ALA A 250 ? THR A 255 ? ALA A 250 THR A 255 D 4 MET A 241 ? GLN A 246 ? MET A 241 GLN A 246 D 5 LYS A 195 ? ILE A 199 ? LYS A 195 ILE A 199 E 1 VAL A 568 ? GLY A 569 ? VAL A 568 GLY A 569 E 2 ALA A 537 ? TRP A 539 ? ALA A 537 TRP A 539 E 3 ILE A 523 ? THR A 525 ? ILE A 523 THR A 525 E 4 GLY A 439 ? ILE A 442 ? GLY A 439 ILE A 442 E 5 LYS A 360 ? VAL A 365 ? LYS A 360 VAL A 365 E 6 VAL A 323 ? ALA A 326 ? VAL A 323 ALA A 326 E 7 HIS A 295 ? LEU A 296 ? HIS A 295 LEU A 296 E 8 ARG A 598 ? ASN A 599 ? ARG A 598 ASN A 599 E 9 ASP A 571 ? ILE A 572 ? ASP A 571 ILE A 572 F 1 ILE A 369 ? SER A 370 ? ILE A 369 SER A 370 F 2 GLY A 408 ? VAL A 411 ? GLY A 408 VAL A 411 F 3 GLY A 403 ? VAL A 405 ? GLY A 403 VAL A 405 G 1 VAL A 487 ? GLN A 488 ? VAL A 487 GLN A 488 G 2 GLY A 491 ? LYS A 492 ? GLY A 491 LYS A 492 H 1 ALA A 652 ? ARG A 653 ? ALA A 652 ARG A 653 H 2 PHE A 672 ? TRP A 674 ? PHE A 672 TRP A 674 H 3 LEU A 678 ? THR A 681 ? LEU A 678 THR A 681 H 4 GLY A 726 ? ARG A 730 ? GLY A 726 ARG A 730 H 5 TRP A 700 ? ASP A 702 ? TRP A 700 ASP A 702 I 1 LYS A 690 ? VAL A 695 ? LYS A 690 VAL A 695 I 2 GLN A 714 ? GLU A 719 ? GLN A 714 GLU A 719 J 1 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 J 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 J 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 J 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 J 5 ALA A 764 ? TRP A 770 ? ALA A 764 TRP A 770 J 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 J 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 J 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 J 9 VAL A 850 ? THR A 854 ? VAL A 850 THR A 854 J 10 THR A 841 ? ASP A 845 ? THR A 841 ASP A 845 K 1 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 K 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 K 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 K 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 K 5 ALA A 764 ? TRP A 770 ? ALA A 764 TRP A 770 K 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 K 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 K 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 K 9 LEU A 858 ? LEU A 859 ? LEU A 858 LEU A 859 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N CYS A 32 ? N CYS A 32 O TYR A 45 ? O TYR A 45 B 1 2 N GLU A 55 ? N GLU A 55 O ARG A 68 ? O ARG A 68 B 2 3 N ALA A 67 ? N ALA A 67 O LEU A 87 ? O LEU A 87 B 3 4 N GLU A 90 ? N GLU A 90 O HIS A 98 ? O HIS A 98 B 4 5 N PHE A 99 ? N PHE A 99 O PHE A 262 ? O PHE A 262 B 5 6 O PHE A 265 ? O PHE A 265 N GLY A 232 ? N GLY A 232 B 6 7 O PHE A 231 ? O PHE A 231 N CYS A 222 ? N CYS A 222 B 7 8 O LEU A 221 ? O LEU A 221 N TYR A 178 ? N TYR A 178 C 1 2 N GLU A 132 ? N GLU A 132 O LYS A 141 ? O LYS A 141 C 2 3 N VAL A 142 ? N VAL A 142 O PHE A 152 ? O PHE A 152 D 1 2 N ALA A 162 ? N ALA A 162 O PHE A 165 ? O PHE A 165 D 2 3 N LEU A 166 ? N LEU A 166 O THR A 255 ? O THR A 255 D 3 4 O THR A 252 ? O THR A 252 N VAL A 244 ? N VAL A 244 D 4 5 O LEU A 245 ? O LEU A 245 N LYS A 195 ? N LYS A 195 E 1 2 O GLY A 569 ? O GLY A 569 N HIS A 538 ? N HIS A 538 E 2 3 O ALA A 537 ? O ALA A 537 N ILE A 523 ? N ILE A 523 E 3 4 O LEU A 524 ? O LEU A 524 N ILE A 442 ? N ILE A 442 E 4 5 O TRP A 441 ? O TRP A 441 N ILE A 363 ? N ILE A 363 E 5 6 O LYS A 360 ? O LYS A 360 N GLN A 324 ? N GLN A 324 E 6 7 O VAL A 323 ? O VAL A 323 N LEU A 296 ? N LEU A 296 E 7 8 N HIS A 295 ? N HIS A 295 O ASN A 599 ? O ASN A 599 E 8 9 O ARG A 598 ? O ARG A 598 N ILE A 572 ? N ILE A 572 F 1 2 N ILE A 369 ? N ILE A 369 O VAL A 411 ? O VAL A 411 F 2 3 O THR A 410 ? O THR A 410 N GLY A 403 ? N GLY A 403 G 1 2 N GLN A 488 ? N GLN A 488 O GLY A 491 ? O GLY A 491 H 1 2 N ARG A 653 ? N ARG A 653 O LEU A 673 ? O LEU A 673 H 2 3 N PHE A 672 ? N PHE A 672 O ILE A 680 ? O ILE A 680 H 3 4 N LEU A 679 ? N LEU A 679 O HIS A 728 ? O HIS A 728 H 4 5 O LEU A 729 ? O LEU A 729 N TYR A 701 ? N TYR A 701 I 1 2 N VAL A 691 ? N VAL A 691 O MET A 718 ? O MET A 718 J 1 2 N LYS A 830 ? N LYS A 830 O THR A 865 ? O THR A 865 J 2 3 O TYR A 864 ? O TYR A 864 N VAL A 798 ? N VAL A 798 J 3 4 O GLU A 797 ? O GLU A 797 N SER A 790 ? N SER A 790 J 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 J 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 J 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 J 7 8 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 J 8 9 N ILE A 818 ? N ILE A 818 O ALA A 851 ? O ALA A 851 J 9 10 O ILE A 852 ? O ILE A 852 N THR A 843 ? N THR A 843 K 1 2 N LYS A 830 ? N LYS A 830 O THR A 865 ? O THR A 865 K 2 3 O TYR A 864 ? O TYR A 864 N VAL A 798 ? N VAL A 798 K 3 4 O GLU A 797 ? O GLU A 797 N SER A 790 ? N SER A 790 K 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 K 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 K 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 K 7 8 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 K 8 9 N PHE A 813 ? N PHE A 813 O LEU A 858 ? O LEU A 858 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 21 'BINDING SITE FOR RESIDUE KTL A 1001' AC2 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE NAG A 2001' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2002' AC4 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 2003' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2004' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2005' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 21 ASP A 203 ? ASP A 203 . ? 1_555 ? 2 AC1 21 TYR A 299 ? TYR A 299 . ? 1_555 ? 3 AC1 21 ASP A 327 ? ASP A 327 . ? 1_555 ? 4 AC1 21 ILE A 364 ? ILE A 364 . ? 1_555 ? 5 AC1 21 TRP A 406 ? TRP A 406 . ? 1_555 ? 6 AC1 21 TRP A 441 ? TRP A 441 . ? 1_555 ? 7 AC1 21 ASP A 443 ? ASP A 443 . ? 1_555 ? 8 AC1 21 ARG A 526 ? ARG A 526 . ? 1_555 ? 9 AC1 21 TRP A 539 ? TRP A 539 . ? 1_555 ? 10 AC1 21 ASP A 542 ? ASP A 542 . ? 1_555 ? 11 AC1 21 PHE A 575 ? PHE A 575 . ? 1_555 ? 12 AC1 21 HIS A 600 ? HIS A 600 . ? 1_555 ? 13 AC1 21 HOH H . ? HOH A 927 . ? 1_555 ? 14 AC1 21 HOH H . ? HOH A 1040 . ? 1_555 ? 15 AC1 21 HOH H . ? HOH A 1041 . ? 1_555 ? 16 AC1 21 HOH H . ? HOH A 1085 . ? 1_555 ? 17 AC1 21 HOH H . ? HOH A 1282 . ? 1_555 ? 18 AC1 21 HOH H . ? HOH A 1295 . ? 1_555 ? 19 AC1 21 HOH H . ? HOH A 1298 . ? 1_555 ? 20 AC1 21 HOH H . ? HOH A 1356 . ? 1_555 ? 21 AC1 21 HOH H . ? HOH A 1518 . ? 1_555 ? 22 AC2 9 SER A 146 ? SER A 146 . ? 2_675 ? 23 AC2 9 ASN A 147 ? ASN A 147 . ? 2_675 ? 24 AC2 9 ASN A 148 ? ASN A 148 . ? 2_675 ? 25 AC2 9 ASN A 741 ? ASN A 741 . ? 1_555 ? 26 AC2 9 ASN A 750 ? ASN A 750 . ? 1_555 ? 27 AC2 9 HOH H . ? HOH A 945 . ? 1_555 ? 28 AC2 9 HOH H . ? HOH A 1089 . ? 1_555 ? 29 AC2 9 HOH H . ? HOH A 1247 . ? 1_555 ? 30 AC2 9 NAG D . ? NAG A 2002 . ? 1_555 ? 31 AC3 3 HOH H . ? HOH A 1173 . ? 2_675 ? 32 AC3 3 HOH H . ? HOH A 1350 . ? 2_675 ? 33 AC3 3 NAG C . ? NAG A 2001 . ? 1_555 ? 34 AC4 10 LYS A 389 ? LYS A 389 . ? 1_555 ? 35 AC4 10 ASN A 393 ? ASN A 393 . ? 1_555 ? 36 AC4 10 GLY A 397 ? GLY A 397 . ? 1_555 ? 37 AC4 10 VAL A 398 ? VAL A 398 . ? 1_555 ? 38 AC4 10 VAL A 487 ? VAL A 487 . ? 1_555 ? 39 AC4 10 GLN A 488 ? GLN A 488 . ? 1_555 ? 40 AC4 10 HIS A 489 ? HIS A 489 . ? 1_555 ? 41 AC4 10 HOH H . ? HOH A 1193 . ? 1_555 ? 42 AC4 10 HOH H . ? HOH A 1449 . ? 1_555 ? 43 AC4 10 NAG F . ? NAG A 2004 . ? 1_555 ? 44 AC5 3 LYS A 389 ? LYS A 389 . ? 1_555 ? 45 AC5 3 HOH H . ? HOH A 1458 . ? 1_555 ? 46 AC5 3 NAG E . ? NAG A 2003 . ? 1_555 ? 47 AC6 3 GLY A 208 ? GLY A 208 . ? 1_555 ? 48 AC6 3 ASN A 209 ? ASN A 209 . ? 1_555 ? 49 AC6 3 HOH H . ? HOH A 1482 . ? 1_555 ? # _atom_sites.entry_id 3L4V _atom_sites.fract_transf_matrix[1][1] 0.010956 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009116 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.009085 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 7 ? 57.864 72.502 -8.520 1.00 47.90 ? 7 VAL A N 1 ATOM 2 C CA . VAL A 1 7 ? 57.998 73.475 -7.395 1.00 47.33 ? 7 VAL A CA 1 ATOM 3 C C . VAL A 1 7 ? 59.129 73.038 -6.448 1.00 46.61 ? 7 VAL A C 1 ATOM 4 O O . VAL A 1 7 ? 59.064 71.957 -5.869 1.00 46.74 ? 7 VAL A O 1 ATOM 5 C CB . VAL A 1 7 ? 56.643 73.635 -6.598 1.00 47.58 ? 7 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 7 ? 56.647 74.889 -5.735 1.00 47.02 ? 7 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 7 ? 55.464 73.703 -7.553 1.00 48.06 ? 7 VAL A CG2 1 ATOM 8 N N . ASN A 1 8 ? 60.168 73.877 -6.328 1.00 45.04 ? 8 ASN A N 1 ATOM 9 C CA . ASN A 1 8 ? 61.108 73.854 -5.193 1.00 42.89 ? 8 ASN A CA 1 ATOM 10 C C . ASN A 1 8 ? 60.268 73.808 -3.908 1.00 41.15 ? 8 ASN A C 1 ATOM 11 O O . ASN A 1 8 ? 59.292 74.550 -3.790 1.00 39.87 ? 8 ASN A O 1 ATOM 12 C CB . ASN A 1 8 ? 62.015 75.105 -5.320 1.00 43.76 ? 8 ASN A CB 1 ATOM 13 C CG . ASN A 1 8 ? 62.703 75.546 -4.010 1.00 45.94 ? 8 ASN A CG 1 ATOM 14 O OD1 . ASN A 1 8 ? 63.111 76.711 -3.904 1.00 49.60 ? 8 ASN A OD1 1 ATOM 15 N ND2 . ASN A 1 8 ? 62.861 74.646 -3.043 1.00 47.51 ? 8 ASN A ND2 1 ATOM 16 N N . GLU A 1 9 ? 60.604 72.917 -2.970 1.00 38.70 ? 9 GLU A N 1 ATOM 17 C CA . GLU A 1 9 ? 59.767 72.738 -1.762 1.00 38.03 ? 9 GLU A CA 1 ATOM 18 C C . GLU A 1 9 ? 59.563 73.962 -0.824 1.00 34.70 ? 9 GLU A C 1 ATOM 19 O O . GLU A 1 9 ? 58.517 74.086 -0.197 1.00 33.95 ? 9 GLU A O 1 ATOM 20 C CB . GLU A 1 9 ? 60.126 71.446 -0.988 1.00 38.32 ? 9 GLU A CB 1 ATOM 21 C CG . GLU A 1 9 ? 61.394 71.446 -0.169 1.00 40.33 ? 9 GLU A CG 1 ATOM 22 C CD . GLU A 1 9 ? 61.698 70.053 0.431 1.00 42.40 ? 9 GLU A CD 1 ATOM 23 O OE1 . GLU A 1 9 ? 61.493 69.020 -0.265 1.00 47.52 ? 9 GLU A OE1 1 ATOM 24 O OE2 . GLU A 1 9 ? 62.157 69.980 1.605 1.00 47.49 ? 9 GLU A OE2 1 ATOM 25 N N . LEU A 1 10 ? 60.529 74.884 -0.801 1.00 31.88 ? 10 LEU A N 1 ATOM 26 C CA . LEU A 1 10 ? 60.451 76.100 0.021 1.00 29.43 ? 10 LEU A CA 1 ATOM 27 C C . LEU A 1 10 ? 59.394 77.061 -0.483 1.00 28.01 ? 10 LEU A C 1 ATOM 28 O O . LEU A 1 10 ? 58.922 77.916 0.283 1.00 27.46 ? 10 LEU A O 1 ATOM 29 C CB . LEU A 1 10 ? 61.823 76.783 0.145 1.00 29.25 ? 10 LEU A CB 1 ATOM 30 C CG . LEU A 1 10 ? 62.885 75.809 0.691 1.00 30.21 ? 10 LEU A CG 1 ATOM 31 C CD1 . LEU A 1 10 ? 64.204 76.466 0.961 1.00 31.76 ? 10 LEU A CD1 1 ATOM 32 C CD2 . LEU A 1 10 ? 62.410 75.041 1.942 1.00 30.76 ? 10 LEU A CD2 1 ATOM 33 N N . GLU A 1 11 ? 58.968 76.863 -1.736 1.00 25.72 ? 11 GLU A N 1 ATOM 34 C CA . GLU A 1 11 ? 58.020 77.746 -2.420 1.00 24.88 ? 11 GLU A CA 1 ATOM 35 C C . GLU A 1 11 ? 56.618 77.202 -2.546 1.00 24.83 ? 11 GLU A C 1 ATOM 36 O O . GLU A 1 11 ? 55.786 77.841 -3.194 1.00 23.82 ? 11 GLU A O 1 ATOM 37 C CB . GLU A 1 11 ? 58.524 78.124 -3.810 1.00 25.27 ? 11 GLU A CB 1 ATOM 38 C CG . GLU A 1 11 ? 59.886 78.782 -3.744 1.00 29.97 ? 11 GLU A CG 1 ATOM 39 C CD . GLU A 1 11 ? 60.558 78.972 -5.081 1.00 35.84 ? 11 GLU A CD 1 ATOM 40 O OE1 . GLU A 1 11 ? 59.923 78.743 -6.130 1.00 36.60 ? 11 GLU A OE1 1 ATOM 41 O OE2 . GLU A 1 11 ? 61.746 79.386 -5.057 1.00 40.97 ? 11 GLU A OE2 1 ATOM 42 N N . ARG A 1 12 ? 56.338 76.038 -1.947 1.00 23.52 ? 12 ARG A N 1 ATOM 43 C CA . ARG A 1 12 ? 54.967 75.510 -2.018 1.00 23.98 ? 12 ARG A CA 1 ATOM 44 C C . ARG A 1 12 ? 54.071 76.318 -1.111 1.00 22.92 ? 12 ARG A C 1 ATOM 45 O O . ARG A 1 12 ? 54.447 76.620 0.028 1.00 22.45 ? 12 ARG A O 1 ATOM 46 C CB . ARG A 1 12 ? 54.904 74.054 -1.612 1.00 24.11 ? 12 ARG A CB 1 ATOM 47 C CG . ARG A 1 12 ? 55.779 73.106 -2.417 1.00 26.60 ? 12 ARG A CG 1 ATOM 48 C CD . ARG A 1 12 ? 55.712 71.731 -1.779 1.00 30.06 ? 12 ARG A CD 1 ATOM 49 N NE . ARG A 1 12 ? 56.604 70.781 -2.434 1.00 36.31 ? 12 ARG A NE 1 ATOM 50 C CZ . ARG A 1 12 ? 56.775 69.513 -2.050 1.00 37.59 ? 12 ARG A CZ 1 ATOM 51 N NH1 . ARG A 1 12 ? 56.106 69.010 -0.999 1.00 36.55 ? 12 ARG A NH1 1 ATOM 52 N NH2 . ARG A 1 12 ? 57.641 68.754 -2.708 1.00 37.90 ? 12 ARG A NH2 1 ATOM 53 N N . ILE A 1 13 ? 52.913 76.708 -1.640 1.00 22.49 ? 13 ILE A N 1 ATOM 54 C CA . ILE A 1 13 ? 51.907 77.478 -0.921 1.00 21.39 ? 13 ILE A CA 1 ATOM 55 C C . ILE A 1 13 ? 50.780 76.503 -0.490 1.00 22.37 ? 13 ILE A C 1 ATOM 56 O O . ILE A 1 13 ? 50.119 75.890 -1.319 1.00 22.54 ? 13 ILE A O 1 ATOM 57 C CB . ILE A 1 13 ? 51.353 78.647 -1.780 1.00 21.56 ? 13 ILE A CB 1 ATOM 58 C CG1 . ILE A 1 13 ? 52.467 79.628 -2.211 1.00 20.14 ? 13 ILE A CG1 1 ATOM 59 C CG2 . ILE A 1 13 ? 50.227 79.373 -1.067 1.00 20.80 ? 13 ILE A CG2 1 ATOM 60 C CD1 . ILE A 1 13 ? 53.272 80.335 -1.084 1.00 17.58 ? 13 ILE A CD1 1 ATOM 61 N N . ASN A 1 14 ? 50.567 76.385 0.813 1.00 22.19 ? 14 ASN A N 1 ATOM 62 C CA . ASN A 1 14 ? 49.752 75.344 1.399 1.00 21.70 ? 14 ASN A CA 1 ATOM 63 C C . ASN A 1 14 ? 48.295 75.467 1.000 1.00 21.74 ? 14 ASN A C 1 ATOM 64 O O . ASN A 1 14 ? 47.650 76.498 1.232 1.00 20.66 ? 14 ASN A O 1 ATOM 65 C CB . ASN A 1 14 ? 49.901 75.425 2.926 1.00 22.15 ? 14 ASN A CB 1 ATOM 66 C CG . ASN A 1 14 ? 49.269 74.223 3.655 1.00 22.36 ? 14 ASN A CG 1 ATOM 67 O OD1 . ASN A 1 14 ? 48.858 73.233 3.032 1.00 18.79 ? 14 ASN A OD1 1 ATOM 68 N ND2 . ASN A 1 14 ? 49.215 74.314 4.983 1.00 18.93 ? 14 ASN A ND2 1 ATOM 69 N N . CYS A 1 15 ? 47.793 74.404 0.379 1.00 23.08 ? 15 CYS A N 1 ATOM 70 C CA . CYS A 1 15 ? 46.398 74.302 -0.051 1.00 23.00 ? 15 CYS A CA 1 ATOM 71 C C . CYS A 1 15 ? 45.494 73.639 1.024 1.00 22.41 ? 15 CYS A C 1 ATOM 72 O O . CYS A 1 15 ? 44.265 73.640 0.916 1.00 22.73 ? 15 CYS A O 1 ATOM 73 C CB . CYS A 1 15 ? 46.335 73.560 -1.412 1.00 22.92 ? 15 CYS A CB 1 ATOM 74 S SG . CYS A 1 15 ? 44.664 73.236 -2.012 1.00 28.20 ? 15 CYS A SG 1 ATOM 75 N N . ILE A 1 16 ? 46.092 73.082 2.068 1.00 22.49 ? 16 ILE A N 1 ATOM 76 C CA . ILE A 1 16 ? 45.290 72.519 3.168 1.00 22.48 ? 16 ILE A CA 1 ATOM 77 C C . ILE A 1 16 ? 45.764 73.098 4.515 1.00 23.00 ? 16 ILE A C 1 ATOM 78 O O . ILE A 1 16 ? 46.382 72.398 5.311 1.00 21.41 ? 16 ILE A O 1 ATOM 79 C CB . ILE A 1 16 ? 45.248 70.912 3.173 1.00 23.20 ? 16 ILE A CB 1 ATOM 80 C CG1 . ILE A 1 16 ? 44.753 70.359 1.820 1.00 19.01 ? 16 ILE A CG1 1 ATOM 81 C CG2 . ILE A 1 16 ? 44.308 70.406 4.271 1.00 22.23 ? 16 ILE A CG2 1 ATOM 82 C CD1 . ILE A 1 16 ? 44.957 68.836 1.634 1.00 21.91 ? 16 ILE A CD1 1 ATOM 83 N N . PRO A 1 17 ? 45.452 74.383 4.771 1.00 23.78 ? 17 PRO A N 1 ATOM 84 C CA . PRO A 1 17 ? 45.847 75.030 6.037 1.00 24.71 ? 17 PRO A CA 1 ATOM 85 C C . PRO A 1 17 ? 44.936 74.617 7.208 1.00 25.59 ? 17 PRO A C 1 ATOM 86 O O . PRO A 1 17 ? 45.247 74.910 8.366 1.00 26.69 ? 17 PRO A O 1 ATOM 87 C CB . PRO A 1 17 ? 45.658 76.507 5.732 1.00 24.59 ? 17 PRO A CB 1 ATOM 88 C CG . PRO A 1 17 ? 44.476 76.523 4.792 1.00 24.03 ? 17 PRO A CG 1 ATOM 89 C CD . PRO A 1 17 ? 44.683 75.303 3.907 1.00 23.44 ? 17 PRO A CD 1 ATOM 90 N N . ASP A 1 18 ? 43.852 73.902 6.899 1.00 26.19 ? 18 ASP A N 1 ATOM 91 C CA . ASP A 1 18 ? 42.729 73.694 7.822 1.00 27.20 ? 18 ASP A CA 1 ATOM 92 C C . ASP A 1 18 ? 42.654 72.310 8.523 1.00 28.01 ? 18 ASP A C 1 ATOM 93 O O . ASP A 1 18 ? 41.898 72.150 9.474 1.00 27.13 ? 18 ASP A O 1 ATOM 94 C CB . ASP A 1 18 ? 41.413 73.953 7.073 1.00 27.02 ? 18 ASP A CB 1 ATOM 95 C CG . ASP A 1 18 ? 41.289 73.111 5.786 1.00 27.81 ? 18 ASP A CG 1 ATOM 96 O OD1 . ASP A 1 18 ? 42.217 73.074 4.974 1.00 26.00 ? 18 ASP A OD1 1 ATOM 97 O OD2 . ASP A 1 18 ? 40.253 72.471 5.573 1.00 32.09 ? 18 ASP A OD2 1 ATOM 98 N N . GLN A 1 19 ? 43.406 71.320 8.029 1.00 28.58 ? 19 GLN A N 1 ATOM 99 C CA . GLN A 1 19 ? 43.308 69.929 8.506 1.00 29.18 ? 19 GLN A CA 1 ATOM 100 C C . GLN A 1 19 ? 44.584 69.175 8.148 1.00 29.55 ? 19 GLN A C 1 ATOM 101 O O . GLN A 1 19 ? 45.346 69.659 7.338 1.00 30.08 ? 19 GLN A O 1 ATOM 102 C CB . GLN A 1 19 ? 42.064 69.245 7.914 1.00 29.38 ? 19 GLN A CB 1 ATOM 103 C CG . GLN A 1 19 ? 42.046 69.064 6.393 1.00 28.19 ? 19 GLN A CG 1 ATOM 104 C CD . GLN A 1 19 ? 40.697 68.627 5.872 1.00 30.16 ? 19 GLN A CD 1 ATOM 105 O OE1 . GLN A 1 19 ? 39.671 69.016 6.413 1.00 36.38 ? 19 GLN A OE1 1 ATOM 106 N NE2 . GLN A 1 19 ? 40.681 67.846 4.808 1.00 25.64 ? 19 GLN A NE2 1 ATOM 107 N N . PRO A 1 20 ? 44.861 68.008 8.784 1.00 30.60 ? 20 PRO A N 1 ATOM 108 C CA . PRO A 1 20 ? 46.019 67.209 8.286 1.00 29.87 ? 20 PRO A CA 1 ATOM 109 C C . PRO A 1 20 ? 45.856 66.795 6.799 1.00 28.75 ? 20 PRO A C 1 ATOM 110 O O . PRO A 1 20 ? 44.735 66.486 6.353 1.00 27.59 ? 20 PRO A O 1 ATOM 111 C CB . PRO A 1 20 ? 46.062 65.979 9.209 1.00 29.67 ? 20 PRO A CB 1 ATOM 112 C CG . PRO A 1 20 ? 44.907 66.075 10.129 1.00 31.01 ? 20 PRO A CG 1 ATOM 113 C CD . PRO A 1 20 ? 44.203 67.397 9.958 1.00 31.14 ? 20 PRO A CD 1 ATOM 114 N N . PRO A 1 21 ? 46.963 66.837 6.033 1.00 27.84 ? 21 PRO A N 1 ATOM 115 C CA . PRO A 1 21 ? 46.855 66.737 4.567 1.00 26.74 ? 21 PRO A CA 1 ATOM 116 C C . PRO A 1 21 ? 46.502 65.332 4.080 1.00 26.53 ? 21 PRO A C 1 ATOM 117 O O . PRO A 1 21 ? 47.075 64.357 4.563 1.00 27.27 ? 21 PRO A O 1 ATOM 118 C CB . PRO A 1 21 ? 48.233 67.167 4.087 1.00 26.19 ? 21 PRO A CB 1 ATOM 119 C CG . PRO A 1 21 ? 49.162 66.875 5.240 1.00 26.36 ? 21 PRO A CG 1 ATOM 120 C CD . PRO A 1 21 ? 48.362 66.988 6.495 1.00 27.40 ? 21 PRO A CD 1 ATOM 121 N N . THR A 1 22 ? 45.520 65.222 3.184 1.00 26.38 ? 22 THR A N 1 ATOM 122 C CA . THR A 1 22 ? 45.174 63.928 2.553 1.00 26.14 ? 22 THR A CA 1 ATOM 123 C C . THR A 1 22 ? 45.091 64.091 1.052 1.00 26.85 ? 22 THR A C 1 ATOM 124 O O . THR A 1 22 ? 44.695 65.146 0.573 1.00 27.01 ? 22 THR A O 1 ATOM 125 C CB . THR A 1 22 ? 43.803 63.346 3.028 1.00 25.12 ? 22 THR A CB 1 ATOM 126 O OG1 . THR A 1 22 ? 42.741 64.217 2.638 1.00 25.54 ? 22 THR A OG1 1 ATOM 127 C CG2 . THR A 1 22 ? 43.757 63.178 4.527 1.00 24.41 ? 22 THR A CG2 1 ATOM 128 N N . LYS A 1 23 ? 45.423 63.043 0.311 1.00 27.90 ? 23 LYS A N 1 ATOM 129 C CA . LYS A 1 23 ? 45.296 63.090 -1.149 1.00 29.54 ? 23 LYS A CA 1 ATOM 130 C C . LYS A 1 23 ? 43.867 63.356 -1.601 1.00 29.08 ? 23 LYS A C 1 ATOM 131 O O . LYS A 1 23 ? 43.637 64.089 -2.559 1.00 29.01 ? 23 LYS A O 1 ATOM 132 C CB . LYS A 1 23 ? 45.898 61.853 -1.842 1.00 29.54 ? 23 LYS A CB 1 ATOM 133 C CG . LYS A 1 23 ? 46.160 62.079 -3.352 1.00 31.34 ? 23 LYS A CG 1 ATOM 134 C CD . LYS A 1 23 ? 46.449 60.766 -4.118 1.00 31.50 ? 23 LYS A CD 1 ATOM 135 C CE . LYS A 1 23 ? 46.859 60.975 -5.599 1.00 34.22 ? 23 LYS A CE 1 ATOM 136 N NZ . LYS A 1 23 ? 45.994 61.907 -6.419 1.00 35.38 ? 23 LYS A NZ 1 ATOM 137 N N . ALA A 1 24 ? 42.902 62.775 -0.908 1.00 29.71 ? 24 ALA A N 1 ATOM 138 C CA . ALA A 1 24 ? 41.510 62.934 -1.292 1.00 30.11 ? 24 ALA A CA 1 ATOM 139 C C . ALA A 1 24 ? 41.033 64.397 -1.213 1.00 30.51 ? 24 ALA A C 1 ATOM 140 O O . ALA A 1 24 ? 40.354 64.892 -2.131 1.00 30.96 ? 24 ALA A O 1 ATOM 141 C CB . ALA A 1 24 ? 40.635 62.031 -0.432 1.00 30.65 ? 24 ALA A CB 1 ATOM 142 N N . THR A 1 25 ? 41.374 65.095 -0.127 1.00 30.55 ? 25 THR A N 1 ATOM 143 C CA . THR A 1 25 ? 41.044 66.524 0.001 1.00 30.85 ? 25 THR A CA 1 ATOM 144 C C . THR A 1 25 ? 41.781 67.372 -1.062 1.00 31.23 ? 25 THR A C 1 ATOM 145 O O . THR A 1 25 ? 41.213 68.294 -1.633 1.00 30.27 ? 25 THR A O 1 ATOM 146 C CB . THR A 1 25 ? 41.360 67.031 1.418 1.00 31.42 ? 25 THR A CB 1 ATOM 147 O OG1 . THR A 1 25 ? 40.463 66.400 2.337 1.00 32.07 ? 25 THR A OG1 1 ATOM 148 C CG2 . THR A 1 25 ? 41.209 68.545 1.527 1.00 28.84 ? 25 THR A CG2 1 ATOM 149 N N . CYS A 1 26 ? 43.039 67.030 -1.319 1.00 32.27 ? 26 CYS A N 1 ATOM 150 C CA . CYS A 1 26 ? 43.850 67.698 -2.341 1.00 33.55 ? 26 CYS A CA 1 ATOM 151 C C . CYS A 1 26 ? 43.220 67.603 -3.738 1.00 33.98 ? 26 CYS A C 1 ATOM 152 O O . CYS A 1 26 ? 43.051 68.621 -4.417 1.00 33.30 ? 26 CYS A O 1 ATOM 153 C CB . CYS A 1 26 ? 45.239 67.065 -2.371 1.00 32.91 ? 26 CYS A CB 1 ATOM 154 S SG . CYS A 1 26 ? 46.428 67.801 -3.561 1.00 36.66 ? 26 CYS A SG 1 ATOM 155 N N . ASP A 1 27 ? 42.881 66.380 -4.157 1.00 34.89 ? 27 ASP A N 1 ATOM 156 C CA . ASP A 1 27 ? 42.226 66.149 -5.451 1.00 36.10 ? 27 ASP A CA 1 ATOM 157 C C . ASP A 1 27 ? 40.915 66.913 -5.520 1.00 36.32 ? 27 ASP A C 1 ATOM 158 O O . ASP A 1 27 ? 40.678 67.610 -6.482 1.00 37.06 ? 27 ASP A O 1 ATOM 159 C CB . ASP A 1 27 ? 41.964 64.658 -5.704 1.00 36.61 ? 27 ASP A CB 1 ATOM 160 C CG . ASP A 1 27 ? 43.230 63.843 -5.815 1.00 38.26 ? 27 ASP A CG 1 ATOM 161 O OD1 . ASP A 1 27 ? 44.339 64.391 -6.023 1.00 42.17 ? 27 ASP A OD1 1 ATOM 162 O OD2 . ASP A 1 27 ? 43.122 62.612 -5.680 1.00 42.67 ? 27 ASP A OD2 1 ATOM 163 N N . GLN A 1 28 ? 40.086 66.809 -4.488 1.00 36.76 ? 28 GLN A N 1 ATOM 164 C CA . GLN A 1 28 ? 38.828 67.564 -4.416 1.00 38.27 ? 28 GLN A CA 1 ATOM 165 C C . GLN A 1 28 ? 39.012 69.086 -4.565 1.00 36.98 ? 28 GLN A C 1 ATOM 166 O O . GLN A 1 28 ? 38.152 69.762 -5.120 1.00 37.14 ? 28 GLN A O 1 ATOM 167 C CB . GLN A 1 28 ? 38.052 67.189 -3.135 1.00 38.00 ? 28 GLN A CB 1 ATOM 168 C CG . GLN A 1 28 ? 37.123 68.238 -2.549 1.00 40.95 ? 28 GLN A CG 1 ATOM 169 C CD . GLN A 1 28 ? 36.935 68.044 -1.017 1.00 43.12 ? 28 GLN A CD 1 ATOM 170 O OE1 . GLN A 1 28 ? 37.065 69.002 -0.217 1.00 47.31 ? 28 GLN A OE1 1 ATOM 171 N NE2 . GLN A 1 28 ? 36.659 66.789 -0.606 1.00 47.22 ? 28 GLN A NE2 1 ATOM 172 N N . ARG A 1 29 ? 40.141 69.612 -4.088 1.00 36.07 ? 29 ARG A N 1 ATOM 173 C CA . ARG A 1 29 ? 40.421 71.046 -4.170 1.00 34.84 ? 29 ARG A CA 1 ATOM 174 C C . ARG A 1 29 ? 41.129 71.419 -5.463 1.00 34.65 ? 29 ARG A C 1 ATOM 175 O O . ARG A 1 29 ? 41.268 72.591 -5.769 1.00 35.12 ? 29 ARG A O 1 ATOM 176 C CB . ARG A 1 29 ? 41.226 71.515 -2.939 1.00 35.29 ? 29 ARG A CB 1 ATOM 177 C CG . ARG A 1 29 ? 40.374 71.489 -1.658 1.00 34.43 ? 29 ARG A CG 1 ATOM 178 C CD . ARG A 1 29 ? 41.154 71.853 -0.426 1.00 33.56 ? 29 ARG A CD 1 ATOM 179 N NE . ARG A 1 29 ? 40.329 71.688 0.774 1.00 29.68 ? 29 ARG A NE 1 ATOM 180 C CZ . ARG A 1 29 ? 40.695 72.059 1.996 1.00 30.68 ? 29 ARG A CZ 1 ATOM 181 N NH1 . ARG A 1 29 ? 41.893 72.634 2.212 1.00 25.53 ? 29 ARG A NH1 1 ATOM 182 N NH2 . ARG A 1 29 ? 39.870 71.840 3.012 1.00 27.53 ? 29 ARG A NH2 1 ATOM 183 N N . GLY A 1 30 ? 41.568 70.418 -6.223 1.00 34.11 ? 30 GLY A N 1 ATOM 184 C CA . GLY A 1 30 ? 42.292 70.650 -7.459 1.00 33.10 ? 30 GLY A CA 1 ATOM 185 C C . GLY A 1 30 ? 43.706 71.124 -7.233 1.00 32.73 ? 30 GLY A C 1 ATOM 186 O O . GLY A 1 30 ? 44.241 71.819 -8.072 1.00 33.17 ? 30 GLY A O 1 ATOM 187 N N . CYS A 1 31 ? 44.319 70.756 -6.107 1.00 32.35 ? 31 CYS A N 1 ATOM 188 C CA . CYS A 1 31 ? 45.701 71.184 -5.797 1.00 31.77 ? 31 CYS A CA 1 ATOM 189 C C . CYS A 1 31 ? 46.687 70.117 -6.167 1.00 31.97 ? 31 CYS A C 1 ATOM 190 O O . CYS A 1 31 ? 46.290 69.129 -6.757 1.00 32.92 ? 31 CYS A O 1 ATOM 191 C CB . CYS A 1 31 ? 45.852 71.613 -4.329 1.00 31.30 ? 31 CYS A CB 1 ATOM 192 S SG . CYS A 1 31 ? 44.870 73.100 -4.030 1.00 30.57 ? 31 CYS A SG 1 ATOM 193 N N . CYS A 1 32 ? 47.956 70.312 -5.836 1.00 31.84 ? 32 CYS A N 1 ATOM 194 C CA . CYS A 1 32 ? 49.000 69.358 -6.164 1.00 33.41 ? 32 CYS A CA 1 ATOM 195 C C . CYS A 1 32 ? 49.395 68.597 -4.936 1.00 33.38 ? 32 CYS A C 1 ATOM 196 O O . CYS A 1 32 ? 49.490 69.182 -3.863 1.00 31.95 ? 32 CYS A O 1 ATOM 197 C CB . CYS A 1 32 ? 50.270 70.055 -6.642 1.00 33.47 ? 32 CYS A CB 1 ATOM 198 S SG . CYS A 1 32 ? 50.027 71.214 -7.956 1.00 38.42 ? 32 CYS A SG 1 ATOM 199 N N . TRP A 1 33 ? 49.696 67.312 -5.124 1.00 34.04 ? 33 TRP A N 1 ATOM 200 C CA . TRP A 1 33 ? 50.015 66.395 -4.032 1.00 35.44 ? 33 TRP A CA 1 ATOM 201 C C . TRP A 1 33 ? 51.452 65.916 -4.161 1.00 36.24 ? 33 TRP A C 1 ATOM 202 O O . TRP A 1 33 ? 51.860 65.445 -5.219 1.00 36.32 ? 33 TRP A O 1 ATOM 203 C CB . TRP A 1 33 ? 49.055 65.191 -4.054 1.00 34.81 ? 33 TRP A CB 1 ATOM 204 C CG . TRP A 1 33 ? 49.276 64.203 -2.944 1.00 35.18 ? 33 TRP A CG 1 ATOM 205 C CD1 . TRP A 1 33 ? 49.841 62.950 -3.053 1.00 36.04 ? 33 TRP A CD1 1 ATOM 206 C CD2 . TRP A 1 33 ? 48.943 64.372 -1.558 1.00 34.60 ? 33 TRP A CD2 1 ATOM 207 N NE1 . TRP A 1 33 ? 49.885 62.345 -1.821 1.00 35.72 ? 33 TRP A NE1 1 ATOM 208 C CE2 . TRP A 1 33 ? 49.346 63.193 -0.884 1.00 35.25 ? 33 TRP A CE2 1 ATOM 209 C CE3 . TRP A 1 33 ? 48.353 65.408 -0.817 1.00 34.68 ? 33 TRP A CE3 1 ATOM 210 C CZ2 . TRP A 1 33 ? 49.167 63.017 0.499 1.00 33.24 ? 33 TRP A CZ2 1 ATOM 211 C CZ3 . TRP A 1 33 ? 48.185 65.233 0.554 1.00 35.19 ? 33 TRP A CZ3 1 ATOM 212 C CH2 . TRP A 1 33 ? 48.596 64.043 1.196 1.00 34.12 ? 33 TRP A CH2 1 ATOM 213 N N . ASN A 1 34 ? 52.215 66.051 -3.085 1.00 37.93 ? 34 ASN A N 1 ATOM 214 C CA . ASN A 1 34 ? 53.555 65.522 -3.019 1.00 39.56 ? 34 ASN A CA 1 ATOM 215 C C . ASN A 1 34 ? 53.954 65.282 -1.559 1.00 41.09 ? 34 ASN A C 1 ATOM 216 O O . ASN A 1 34 ? 54.618 66.120 -0.939 1.00 40.72 ? 34 ASN A O 1 ATOM 217 C CB . ASN A 1 34 ? 54.551 66.453 -3.718 1.00 39.93 ? 34 ASN A CB 1 ATOM 218 C CG . ASN A 1 34 ? 55.917 65.805 -3.909 1.00 42.06 ? 34 ASN A CG 1 ATOM 219 O OD1 . ASN A 1 34 ? 56.426 65.108 -3.024 1.00 43.22 ? 34 ASN A OD1 1 ATOM 220 N ND2 . ASN A 1 34 ? 56.520 66.038 -5.070 1.00 44.28 ? 34 ASN A ND2 1 ATOM 221 N N . PRO A 1 35 ? 53.589 64.107 -1.013 1.00 42.50 ? 35 PRO A N 1 ATOM 222 C CA . PRO A 1 35 ? 53.806 63.827 0.397 1.00 43.60 ? 35 PRO A CA 1 ATOM 223 C C . PRO A 1 35 ? 55.277 63.701 0.766 1.00 44.60 ? 35 PRO A C 1 ATOM 224 O O . PRO A 1 35 ? 55.593 63.351 1.895 1.00 45.38 ? 35 PRO A O 1 ATOM 225 C CB . PRO A 1 35 ? 53.078 62.501 0.607 1.00 43.38 ? 35 PRO A CB 1 ATOM 226 C CG . PRO A 1 35 ? 53.123 61.861 -0.700 1.00 43.57 ? 35 PRO A CG 1 ATOM 227 C CD . PRO A 1 35 ? 52.991 62.958 -1.706 1.00 42.51 ? 35 PRO A CD 1 ATOM 228 N N . GLN A 1 36 ? 56.171 64.006 -0.163 1.00 46.26 ? 36 GLN A N 1 ATOM 229 C CA . GLN A 1 36 ? 57.596 64.030 0.160 1.00 48.11 ? 36 GLN A CA 1 ATOM 230 C C . GLN A 1 36 ? 58.116 65.472 0.409 1.00 48.33 ? 36 GLN A C 1 ATOM 231 O O . GLN A 1 36 ? 57.911 66.383 -0.415 1.00 49.05 ? 36 GLN A O 1 ATOM 232 C CB . GLN A 1 36 ? 58.429 63.247 -0.886 1.00 48.94 ? 36 GLN A CB 1 ATOM 233 C CG . GLN A 1 36 ? 58.701 61.729 -0.512 1.00 52.77 ? 36 GLN A CG 1 ATOM 234 C CD . GLN A 1 36 ? 57.688 60.683 -1.090 1.00 57.73 ? 36 GLN A CD 1 ATOM 235 O OE1 . GLN A 1 36 ? 58.096 59.649 -1.644 1.00 59.88 ? 36 GLN A OE1 1 ATOM 236 N NE2 . GLN A 1 36 ? 56.386 60.939 -0.936 1.00 59.36 ? 36 GLN A NE2 1 ATOM 237 N N . GLY A 1 37 ? 58.762 65.670 1.561 1.00 47.43 ? 37 GLY A N 1 ATOM 238 C CA . GLY A 1 37 ? 59.266 66.981 1.956 1.00 46.20 ? 37 GLY A CA 1 ATOM 239 C C . GLY A 1 37 ? 59.640 67.013 3.427 1.00 45.63 ? 37 GLY A C 1 ATOM 240 O O . GLY A 1 37 ? 59.083 66.255 4.244 1.00 45.46 ? 37 GLY A O 1 ATOM 241 N N . ALA A 1 38 ? 60.606 67.875 3.760 1.00 44.61 ? 38 ALA A N 1 ATOM 242 C CA . ALA A 1 38 ? 61.023 68.098 5.148 1.00 43.22 ? 38 ALA A CA 1 ATOM 243 C C . ALA A 1 38 ? 59.837 68.517 6.052 1.00 41.90 ? 38 ALA A C 1 ATOM 244 O O . ALA A 1 38 ? 58.774 68.898 5.566 1.00 42.12 ? 38 ALA A O 1 ATOM 245 C CB . ALA A 1 38 ? 62.147 69.157 5.188 1.00 43.60 ? 38 ALA A CB 1 ATOM 246 N N . VAL A 1 39 ? 60.023 68.454 7.360 1.00 40.25 ? 39 VAL A N 1 ATOM 247 C CA . VAL A 1 39 ? 58.966 68.842 8.291 1.00 39.15 ? 39 VAL A CA 1 ATOM 248 C C . VAL A 1 39 ? 58.363 70.232 7.969 1.00 37.37 ? 39 VAL A C 1 ATOM 249 O O . VAL A 1 39 ? 59.091 71.181 7.654 1.00 37.74 ? 39 VAL A O 1 ATOM 250 C CB . VAL A 1 39 ? 59.444 68.730 9.770 1.00 39.50 ? 39 VAL A CB 1 ATOM 251 C CG1 . VAL A 1 39 ? 60.384 69.877 10.144 1.00 39.76 ? 39 VAL A CG1 1 ATOM 252 C CG2 . VAL A 1 39 ? 58.236 68.627 10.734 1.00 40.57 ? 39 VAL A CG2 1 ATOM 253 N N . SER A 1 40 ? 57.041 70.331 8.046 1.00 34.70 ? 40 SER A N 1 ATOM 254 C CA . SER A 1 40 ? 56.287 71.602 7.798 1.00 32.67 ? 40 SER A CA 1 ATOM 255 C C . SER A 1 40 ? 56.063 71.968 6.327 1.00 30.22 ? 40 SER A C 1 ATOM 256 O O . SER A 1 40 ? 55.230 72.826 6.018 1.00 29.11 ? 40 SER A O 1 ATOM 257 C CB . SER A 1 40 ? 56.899 72.796 8.538 1.00 32.54 ? 40 SER A CB 1 ATOM 258 O OG . SER A 1 40 ? 56.823 72.624 9.935 1.00 34.46 ? 40 SER A OG 1 ATOM 259 N N . VAL A 1 41 ? 56.787 71.309 5.437 1.00 27.95 ? 41 VAL A N 1 ATOM 260 C CA . VAL A 1 41 ? 56.602 71.502 4.013 1.00 27.40 ? 41 VAL A CA 1 ATOM 261 C C . VAL A 1 41 ? 55.209 70.938 3.671 1.00 27.45 ? 41 VAL A C 1 ATOM 262 O O . VAL A 1 41 ? 54.906 69.789 4.005 1.00 27.38 ? 41 VAL A O 1 ATOM 263 C CB . VAL A 1 41 ? 57.750 70.820 3.212 1.00 27.49 ? 41 VAL A CB 1 ATOM 264 C CG1 . VAL A 1 41 ? 57.550 70.904 1.698 1.00 27.14 ? 41 VAL A CG1 1 ATOM 265 C CG2 . VAL A 1 41 ? 59.096 71.406 3.591 1.00 25.58 ? 41 VAL A CG2 1 ATOM 266 N N . PRO A 1 42 ? 54.356 71.754 3.026 1.00 27.40 ? 42 PRO A N 1 ATOM 267 C CA . PRO A 1 42 ? 53.009 71.309 2.685 1.00 26.94 ? 42 PRO A CA 1 ATOM 268 C C . PRO A 1 42 ? 53.013 70.138 1.692 1.00 27.20 ? 42 PRO A C 1 ATOM 269 O O . PRO A 1 42 ? 53.593 70.214 0.601 1.00 27.26 ? 42 PRO A O 1 ATOM 270 C CB . PRO A 1 42 ? 52.351 72.540 2.046 1.00 27.05 ? 42 PRO A CB 1 ATOM 271 C CG . PRO A 1 42 ? 53.395 73.578 1.886 1.00 26.73 ? 42 PRO A CG 1 ATOM 272 C CD . PRO A 1 42 ? 54.654 73.121 2.549 1.00 27.35 ? 42 PRO A CD 1 ATOM 273 N N . TRP A 1 43 ? 52.348 69.062 2.080 1.00 27.63 ? 43 TRP A N 1 ATOM 274 C CA . TRP A 1 43 ? 52.079 67.930 1.178 1.00 27.87 ? 43 TRP A CA 1 ATOM 275 C C . TRP A 1 43 ? 51.162 68.334 0.054 1.00 26.34 ? 43 TRP A C 1 ATOM 276 O O . TRP A 1 43 ? 51.226 67.799 -1.040 1.00 25.98 ? 43 TRP A O 1 ATOM 277 C CB . TRP A 1 43 ? 51.442 66.792 1.985 1.00 29.21 ? 43 TRP A CB 1 ATOM 278 C CG . TRP A 1 43 ? 52.438 66.071 2.823 1.00 31.00 ? 43 TRP A CG 1 ATOM 279 C CD1 . TRP A 1 43 ? 53.758 66.404 3.003 1.00 31.93 ? 43 TRP A CD1 1 ATOM 280 C CD2 . TRP A 1 43 ? 52.207 64.886 3.596 1.00 32.96 ? 43 TRP A CD2 1 ATOM 281 N NE1 . TRP A 1 43 ? 54.362 65.493 3.841 1.00 33.66 ? 43 TRP A NE1 1 ATOM 282 C CE2 . TRP A 1 43 ? 53.435 64.550 4.216 1.00 33.66 ? 43 TRP A CE2 1 ATOM 283 C CE3 . TRP A 1 43 ? 51.079 64.072 3.822 1.00 32.88 ? 43 TRP A CE3 1 ATOM 284 C CZ2 . TRP A 1 43 ? 53.570 63.440 5.060 1.00 33.14 ? 43 TRP A CZ2 1 ATOM 285 C CZ3 . TRP A 1 43 ? 51.206 62.978 4.660 1.00 32.26 ? 43 TRP A CZ3 1 ATOM 286 C CH2 . TRP A 1 43 ? 52.452 62.668 5.269 1.00 33.08 ? 43 TRP A CH2 1 ATOM 287 N N . CYS A 1 44 ? 50.304 69.299 0.335 1.00 26.78 ? 44 CYS A N 1 ATOM 288 C CA . CYS A 1 44 ? 49.312 69.740 -0.630 1.00 26.62 ? 44 CYS A CA 1 ATOM 289 C C . CYS A 1 44 ? 49.381 71.257 -0.845 1.00 26.93 ? 44 CYS A C 1 ATOM 290 O O . CYS A 1 44 ? 49.276 72.036 0.112 1.00 26.23 ? 44 CYS A O 1 ATOM 291 C CB . CYS A 1 44 ? 47.919 69.302 -0.203 1.00 25.28 ? 44 CYS A CB 1 ATOM 292 S SG . CYS A 1 44 ? 46.672 69.929 -1.338 1.00 27.06 ? 44 CYS A SG 1 ATOM 293 N N . TYR A 1 45 ? 49.543 71.657 -2.108 1.00 28.27 ? 45 TYR A N 1 ATOM 294 C CA . TYR A 1 45 ? 49.891 73.044 -2.463 1.00 29.71 ? 45 TYR A CA 1 ATOM 295 C C . TYR A 1 45 ? 49.232 73.490 -3.745 1.00 30.33 ? 45 TYR A C 1 ATOM 296 O O . TYR A 1 45 ? 48.852 72.657 -4.568 1.00 30.10 ? 45 TYR A O 1 ATOM 297 C CB . TYR A 1 45 ? 51.407 73.252 -2.539 1.00 30.31 ? 45 TYR A CB 1 ATOM 298 C CG . TYR A 1 45 ? 52.179 72.364 -3.478 1.00 31.64 ? 45 TYR A CG 1 ATOM 299 C CD1 . TYR A 1 45 ? 52.502 72.790 -4.766 1.00 32.95 ? 45 TYR A CD1 1 ATOM 300 C CD2 . TYR A 1 45 ? 52.649 71.117 -3.061 1.00 32.35 ? 45 TYR A CD2 1 ATOM 301 C CE1 . TYR A 1 45 ? 53.232 71.982 -5.626 1.00 31.97 ? 45 TYR A CE1 1 ATOM 302 C CE2 . TYR A 1 45 ? 53.392 70.301 -3.915 1.00 32.59 ? 45 TYR A CE2 1 ATOM 303 C CZ . TYR A 1 45 ? 53.677 70.733 -5.196 1.00 32.39 ? 45 TYR A CZ 1 ATOM 304 O OH . TYR A 1 45 ? 54.416 69.911 -6.041 1.00 32.64 ? 45 TYR A OH 1 ATOM 305 N N . TYR A 1 46 ? 49.065 74.796 -3.908 1.00 30.74 ? 46 TYR A N 1 ATOM 306 C CA . TYR A 1 46 ? 48.383 75.321 -5.075 1.00 33.45 ? 46 TYR A CA 1 ATOM 307 C C . TYR A 1 46 ? 49.258 75.116 -6.319 1.00 35.59 ? 46 TYR A C 1 ATOM 308 O O . TYR A 1 46 ? 50.488 75.189 -6.230 1.00 35.82 ? 46 TYR A O 1 ATOM 309 C CB . TYR A 1 46 ? 48.007 76.787 -4.868 1.00 32.14 ? 46 TYR A CB 1 ATOM 310 C CG . TYR A 1 46 ? 47.014 77.010 -3.754 1.00 29.60 ? 46 TYR A CG 1 ATOM 311 C CD1 . TYR A 1 46 ? 45.652 76.771 -3.942 1.00 28.91 ? 46 TYR A CD1 1 ATOM 312 C CD2 . TYR A 1 46 ? 47.434 77.475 -2.503 1.00 28.82 ? 46 TYR A CD2 1 ATOM 313 C CE1 . TYR A 1 46 ? 44.732 76.980 -2.898 1.00 27.60 ? 46 TYR A CE1 1 ATOM 314 C CE2 . TYR A 1 46 ? 46.523 77.711 -1.465 1.00 26.21 ? 46 TYR A CE2 1 ATOM 315 C CZ . TYR A 1 46 ? 45.181 77.444 -1.671 1.00 28.43 ? 46 TYR A CZ 1 ATOM 316 O OH . TYR A 1 46 ? 44.285 77.673 -0.638 1.00 30.15 ? 46 TYR A OH 1 ATOM 317 N N . SER A 1 47 ? 48.631 74.792 -7.447 1.00 39.22 ? 47 SER A N 1 ATOM 318 C CA . SER A 1 47 ? 49.363 74.601 -8.726 1.00 43.39 ? 47 SER A CA 1 ATOM 319 C C . SER A 1 47 ? 49.945 75.898 -9.274 1.00 45.77 ? 47 SER A C 1 ATOM 320 O O . SER A 1 47 ? 49.495 76.988 -8.879 1.00 46.48 ? 47 SER A O 1 ATOM 321 C CB . SER A 1 47 ? 48.451 73.990 -9.795 1.00 42.85 ? 47 SER A CB 1 ATOM 322 O OG . SER A 1 47 ? 47.134 74.502 -9.689 1.00 44.60 ? 47 SER A OG 1 ATOM 323 N N . LYS A 1 48 ? 50.933 75.778 -10.178 1.00 48.67 ? 48 LYS A N 1 ATOM 324 C CA . LYS A 1 48 ? 51.450 76.915 -10.991 1.00 50.80 ? 48 LYS A CA 1 ATOM 325 C C . LYS A 1 48 ? 50.277 77.757 -11.503 1.00 51.44 ? 48 LYS A C 1 ATOM 326 O O . LYS A 1 48 ? 50.186 78.954 -11.209 1.00 52.15 ? 48 LYS A O 1 ATOM 327 C CB . LYS A 1 48 ? 52.275 76.422 -12.202 1.00 51.21 ? 48 LYS A CB 1 ATOM 328 C CG . LYS A 1 48 ? 53.696 75.850 -11.920 1.00 53.64 ? 48 LYS A CG 1 ATOM 329 C CD . LYS A 1 48 ? 54.830 76.772 -12.456 1.00 55.94 ? 48 LYS A CD 1 ATOM 330 C CE . LYS A 1 48 ? 54.906 76.791 -14.005 1.00 56.71 ? 48 LYS A CE 1 ATOM 331 N NZ . LYS A 1 48 ? 55.706 77.945 -14.563 1.00 55.75 ? 48 LYS A NZ 1 ATOM 332 N N . ASN A 1 49 ? 49.373 77.123 -12.248 1.00 51.94 ? 49 ASN A N 1 ATOM 333 C CA . ASN A 1 49 ? 48.217 77.814 -12.797 1.00 52.77 ? 49 ASN A CA 1 ATOM 334 C C . ASN A 1 49 ? 46.964 77.605 -11.959 1.00 52.65 ? 49 ASN A C 1 ATOM 335 O O . ASN A 1 49 ? 47.024 76.948 -10.917 1.00 53.69 ? 49 ASN A O 1 ATOM 336 C CB . ASN A 1 49 ? 48.011 77.482 -14.292 1.00 53.39 ? 49 ASN A CB 1 ATOM 337 C CG . ASN A 1 49 ? 48.712 78.500 -15.235 1.00 54.23 ? 49 ASN A CG 1 ATOM 338 O OD1 . ASN A 1 49 ? 48.064 79.400 -15.786 1.00 55.54 ? 49 ASN A OD1 1 ATOM 339 N ND2 . ASN A 1 49 ? 50.035 78.362 -15.402 1.00 53.93 ? 49 ASN A ND2 1 ATOM 340 N N . HIS A 1 50 ? 45.839 78.153 -12.426 1.00 52.28 ? 50 HIS A N 1 ATOM 341 C CA . HIS A 1 50 ? 44.612 78.378 -11.631 1.00 51.28 ? 50 HIS A CA 1 ATOM 342 C C . HIS A 1 50 ? 44.821 79.618 -10.771 1.00 49.47 ? 50 HIS A C 1 ATOM 343 O O . HIS A 1 50 ? 45.974 79.956 -10.468 1.00 50.42 ? 50 HIS A O 1 ATOM 344 C CB . HIS A 1 50 ? 44.211 77.192 -10.741 1.00 51.91 ? 50 HIS A CB 1 ATOM 345 C CG . HIS A 1 50 ? 43.673 77.607 -9.396 1.00 54.85 ? 50 HIS A CG 1 ATOM 346 N ND1 . HIS A 1 50 ? 44.356 77.386 -8.213 1.00 57.54 ? 50 HIS A ND1 1 ATOM 347 C CD2 . HIS A 1 50 ? 42.524 78.245 -9.049 1.00 57.08 ? 50 HIS A CD2 1 ATOM 348 C CE1 . HIS A 1 50 ? 43.645 77.852 -7.198 1.00 57.39 ? 50 HIS A CE1 1 ATOM 349 N NE2 . HIS A 1 50 ? 42.537 78.392 -7.678 1.00 58.53 ? 50 HIS A NE2 1 ATOM 350 N N . SER A 1 51 ? 43.710 80.256 -10.369 1.00 46.31 ? 51 SER A N 1 ATOM 351 C CA . SER A 1 51 ? 43.681 81.500 -9.589 1.00 43.62 ? 51 SER A CA 1 ATOM 352 C C . SER A 1 51 ? 42.745 82.467 -10.345 1.00 41.14 ? 51 SER A C 1 ATOM 353 O O . SER A 1 51 ? 41.597 82.111 -10.648 1.00 41.78 ? 51 SER A O 1 ATOM 354 C CB . SER A 1 51 ? 45.108 82.095 -9.411 1.00 43.83 ? 51 SER A CB 1 ATOM 355 O OG . SER A 1 51 ? 45.112 83.392 -8.825 1.00 43.20 ? 51 SER A OG 1 ATOM 356 N N . TYR A 1 52 ? 43.247 83.667 -10.641 1.00 37.01 ? 52 TYR A N 1 ATOM 357 C CA . TYR A 1 52 ? 42.594 84.653 -11.486 1.00 33.08 ? 52 TYR A CA 1 ATOM 358 C C . TYR A 1 52 ? 43.500 84.947 -12.688 1.00 31.58 ? 52 TYR A C 1 ATOM 359 O O . TYR A 1 52 ? 44.695 84.719 -12.635 1.00 29.53 ? 52 TYR A O 1 ATOM 360 C CB . TYR A 1 52 ? 42.380 85.930 -10.692 1.00 32.32 ? 52 TYR A CB 1 ATOM 361 C CG . TYR A 1 52 ? 41.252 85.855 -9.696 1.00 31.17 ? 52 TYR A CG 1 ATOM 362 C CD1 . TYR A 1 52 ? 41.425 85.237 -8.456 1.00 29.82 ? 52 TYR A CD1 1 ATOM 363 C CD2 . TYR A 1 52 ? 40.025 86.414 -9.991 1.00 29.31 ? 52 TYR A CD2 1 ATOM 364 C CE1 . TYR A 1 52 ? 40.381 85.166 -7.537 1.00 30.97 ? 52 TYR A CE1 1 ATOM 365 C CE2 . TYR A 1 52 ? 38.975 86.361 -9.087 1.00 31.04 ? 52 TYR A CE2 1 ATOM 366 C CZ . TYR A 1 52 ? 39.168 85.729 -7.862 1.00 31.24 ? 52 TYR A CZ 1 ATOM 367 O OH . TYR A 1 52 ? 38.136 85.682 -6.985 1.00 30.83 ? 52 TYR A OH 1 ATOM 368 N N . HIS A 1 53 ? 42.926 85.433 -13.778 1.00 30.51 ? 53 HIS A N 1 ATOM 369 C CA . HIS A 1 53 ? 43.731 85.911 -14.903 1.00 30.12 ? 53 HIS A CA 1 ATOM 370 C C . HIS A 1 53 ? 43.314 87.338 -15.180 1.00 29.16 ? 53 HIS A C 1 ATOM 371 O O . HIS A 1 53 ? 42.201 87.734 -14.839 1.00 28.42 ? 53 HIS A O 1 ATOM 372 C CB . HIS A 1 53 ? 43.551 85.028 -16.166 1.00 30.17 ? 53 HIS A CB 1 ATOM 373 C CG . HIS A 1 53 ? 42.168 85.062 -16.750 1.00 33.21 ? 53 HIS A CG 1 ATOM 374 N ND1 . HIS A 1 53 ? 41.747 86.047 -17.620 1.00 35.14 ? 53 HIS A ND1 1 ATOM 375 C CD2 . HIS A 1 53 ? 41.112 84.222 -16.600 1.00 34.27 ? 53 HIS A CD2 1 ATOM 376 C CE1 . HIS A 1 53 ? 40.493 85.817 -17.974 1.00 35.62 ? 53 HIS A CE1 1 ATOM 377 N NE2 . HIS A 1 53 ? 40.084 84.715 -17.370 1.00 34.60 ? 53 HIS A NE2 1 ATOM 378 N N . VAL A 1 54 ? 44.184 88.120 -15.818 1.00 28.50 ? 54 VAL A N 1 ATOM 379 C CA . VAL A 1 54 ? 43.766 89.458 -16.212 1.00 28.35 ? 54 VAL A CA 1 ATOM 380 C C . VAL A 1 54 ? 42.879 89.362 -17.439 1.00 28.42 ? 54 VAL A C 1 ATOM 381 O O . VAL A 1 54 ? 43.233 88.688 -18.400 1.00 28.66 ? 54 VAL A O 1 ATOM 382 C CB . VAL A 1 54 ? 44.961 90.413 -16.474 1.00 27.94 ? 54 VAL A CB 1 ATOM 383 C CG1 . VAL A 1 54 ? 44.442 91.818 -16.859 1.00 26.23 ? 54 VAL A CG1 1 ATOM 384 C CG2 . VAL A 1 54 ? 45.848 90.471 -15.245 1.00 26.66 ? 54 VAL A CG2 1 ATOM 385 N N . GLU A 1 55 ? 41.747 90.047 -17.402 1.00 28.98 ? 55 GLU A N 1 ATOM 386 C CA . GLU A 1 55 ? 40.854 90.100 -18.548 1.00 30.61 ? 55 GLU A CA 1 ATOM 387 C C . GLU A 1 55 ? 41.019 91.412 -19.346 1.00 29.74 ? 55 GLU A C 1 ATOM 388 O O . GLU A 1 55 ? 40.788 92.498 -18.825 1.00 29.36 ? 55 GLU A O 1 ATOM 389 C CB . GLU A 1 55 ? 39.389 89.889 -18.111 1.00 30.67 ? 55 GLU A CB 1 ATOM 390 C CG . GLU A 1 55 ? 38.374 89.936 -19.277 1.00 36.46 ? 55 GLU A CG 1 ATOM 391 C CD . GLU A 1 55 ? 38.155 88.586 -20.013 1.00 44.33 ? 55 GLU A CD 1 ATOM 392 O OE1 . GLU A 1 55 ? 39.076 87.721 -20.089 1.00 45.92 ? 55 GLU A OE1 1 ATOM 393 O OE2 . GLU A 1 55 ? 37.027 88.394 -20.544 1.00 48.66 ? 55 GLU A OE2 1 ATOM 394 N N . GLY A 1 56 ? 41.385 91.298 -20.621 1.00 29.97 ? 56 GLY A N 1 ATOM 395 C CA . GLY A 1 56 ? 41.601 92.489 -21.465 1.00 29.46 ? 56 GLY A CA 1 ATOM 396 C C . GLY A 1 56 ? 42.789 93.311 -20.962 1.00 28.93 ? 56 GLY A C 1 ATOM 397 O O . GLY A 1 56 ? 43.701 92.747 -20.357 1.00 28.00 ? 56 GLY A O 1 ATOM 398 N N . ASN A 1 57 ? 42.764 94.631 -21.191 1.00 28.34 ? 57 ASN A N 1 ATOM 399 C CA . ASN A 1 57 ? 43.920 95.489 -20.903 1.00 28.23 ? 57 ASN A CA 1 ATOM 400 C C . ASN A 1 57 ? 43.780 96.232 -19.577 1.00 28.76 ? 57 ASN A C 1 ATOM 401 O O . ASN A 1 57 ? 42.656 96.458 -19.075 1.00 29.47 ? 57 ASN A O 1 ATOM 402 C CB . ASN A 1 57 ? 44.158 96.536 -22.023 1.00 27.48 ? 57 ASN A CB 1 ATOM 403 C CG . ASN A 1 57 ? 44.431 95.919 -23.395 1.00 27.45 ? 57 ASN A CG 1 ATOM 404 O OD1 . ASN A 1 57 ? 44.906 94.788 -23.523 1.00 25.05 ? 57 ASN A OD1 1 ATOM 405 N ND2 . ASN A 1 57 ? 44.145 96.682 -24.430 1.00 27.33 ? 57 ASN A ND2 1 ATOM 406 N N . LEU A 1 58 ? 44.926 96.671 -19.055 1.00 28.27 ? 58 LEU A N 1 ATOM 407 C CA . LEU A 1 58 ? 44.967 97.666 -17.982 1.00 27.15 ? 58 LEU A CA 1 ATOM 408 C C . LEU A 1 58 ? 44.549 99.025 -18.518 1.00 26.38 ? 58 LEU A C 1 ATOM 409 O O . LEU A 1 58 ? 44.752 99.326 -19.699 1.00 25.74 ? 58 LEU A O 1 ATOM 410 C CB . LEU A 1 58 ? 46.356 97.741 -17.334 1.00 26.87 ? 58 LEU A CB 1 ATOM 411 C CG . LEU A 1 58 ? 46.710 96.628 -16.345 1.00 27.47 ? 58 LEU A CG 1 ATOM 412 C CD1 . LEU A 1 58 ? 46.608 95.186 -16.921 1.00 27.58 ? 58 LEU A CD1 1 ATOM 413 C CD2 . LEU A 1 58 ? 48.080 96.867 -15.790 1.00 23.87 ? 58 LEU A CD2 1 ATOM 414 N N . VAL A 1 59 ? 43.943 99.816 -17.637 1.00 25.68 ? 59 VAL A N 1 ATOM 415 C CA . VAL A 1 59 ? 43.395 101.139 -17.938 1.00 25.59 ? 59 VAL A CA 1 ATOM 416 C C . VAL A 1 59 ? 44.188 102.139 -17.126 1.00 25.49 ? 59 VAL A C 1 ATOM 417 O O . VAL A 1 59 ? 44.171 102.062 -15.911 1.00 24.05 ? 59 VAL A O 1 ATOM 418 C CB . VAL A 1 59 ? 41.891 101.226 -17.524 1.00 25.36 ? 59 VAL A CB 1 ATOM 419 C CG1 . VAL A 1 59 ? 41.300 102.653 -17.705 1.00 25.97 ? 59 VAL A CG1 1 ATOM 420 C CG2 . VAL A 1 59 ? 41.053 100.170 -18.325 1.00 26.92 ? 59 VAL A CG2 1 ATOM 421 N N . ASN A 1 60 ? 44.883 103.066 -17.794 1.00 25.47 ? 60 ASN A N 1 ATOM 422 C CA . ASN A 1 60 ? 45.472 104.217 -17.107 1.00 26.77 ? 60 ASN A CA 1 ATOM 423 C C . ASN A 1 60 ? 44.435 105.102 -16.474 1.00 27.01 ? 60 ASN A C 1 ATOM 424 O O . ASN A 1 60 ? 43.423 105.440 -17.099 1.00 27.62 ? 60 ASN A O 1 ATOM 425 C CB . ASN A 1 60 ? 46.269 105.103 -18.062 1.00 27.54 ? 60 ASN A CB 1 ATOM 426 C CG . ASN A 1 60 ? 47.597 104.514 -18.411 1.00 30.89 ? 60 ASN A CG 1 ATOM 427 O OD1 . ASN A 1 60 ? 48.600 104.735 -17.709 1.00 34.91 ? 60 ASN A OD1 1 ATOM 428 N ND2 . ASN A 1 60 ? 47.632 103.758 -19.506 1.00 30.63 ? 60 ASN A ND2 1 ATOM 429 N N . THR A 1 61 ? 44.698 105.491 -15.238 1.00 26.42 ? 61 THR A N 1 ATOM 430 C CA . THR A 1 61 ? 43.878 106.441 -14.533 1.00 27.11 ? 61 THR A CA 1 ATOM 431 C C . THR A 1 61 ? 44.840 107.565 -14.111 1.00 27.94 ? 61 THR A C 1 ATOM 432 O O . THR A 1 61 ? 46.072 107.454 -14.291 1.00 27.21 ? 61 THR A O 1 ATOM 433 C CB . THR A 1 61 ? 43.237 105.812 -13.273 1.00 27.39 ? 61 THR A CB 1 ATOM 434 O OG1 . THR A 1 61 ? 44.279 105.328 -12.447 1.00 26.70 ? 61 THR A OG1 1 ATOM 435 C CG2 . THR A 1 61 ? 42.309 104.605 -13.613 1.00 26.08 ? 61 THR A CG2 1 ATOM 436 N N . ASN A 1 62 ? 44.269 108.644 -13.579 1.00 28.83 ? 62 ASN A N 1 ATOM 437 C CA . ASN A 1 62 ? 45.053 109.751 -13.041 1.00 29.25 ? 62 ASN A CA 1 ATOM 438 C C . ASN A 1 62 ? 46.008 109.307 -11.940 1.00 28.25 ? 62 ASN A C 1 ATOM 439 O O . ASN A 1 62 ? 47.161 109.712 -11.960 1.00 29.07 ? 62 ASN A O 1 ATOM 440 C CB . ASN A 1 62 ? 44.141 110.876 -12.552 1.00 29.85 ? 62 ASN A CB 1 ATOM 441 C CG . ASN A 1 62 ? 43.436 111.596 -13.690 1.00 32.43 ? 62 ASN A CG 1 ATOM 442 O OD1 . ASN A 1 62 ? 42.370 112.162 -13.489 1.00 35.03 ? 62 ASN A OD1 1 ATOM 443 N ND2 . ASN A 1 62 ? 44.034 111.590 -14.890 1.00 34.25 ? 62 ASN A ND2 1 ATOM 444 N N . ALA A 1 63 ? 45.544 108.453 -11.023 1.00 26.80 ? 63 ALA A N 1 ATOM 445 C CA . ALA A 1 63 ? 46.344 107.957 -9.891 1.00 25.35 ? 63 ALA A CA 1 ATOM 446 C C . ALA A 1 63 ? 47.301 106.815 -10.242 1.00 25.35 ? 63 ALA A C 1 ATOM 447 O O . ALA A 1 63 ? 48.333 106.641 -9.578 1.00 25.22 ? 63 ALA A O 1 ATOM 448 C CB . ALA A 1 63 ? 45.421 107.506 -8.747 1.00 26.40 ? 63 ALA A CB 1 ATOM 449 N N . GLY A 1 64 ? 46.973 106.034 -11.269 1.00 24.22 ? 64 GLY A N 1 ATOM 450 C CA . GLY A 1 64 ? 47.774 104.853 -11.629 1.00 23.91 ? 64 GLY A CA 1 ATOM 451 C C . GLY A 1 64 ? 47.084 104.009 -12.713 1.00 24.17 ? 64 GLY A C 1 ATOM 452 O O . GLY A 1 64 ? 47.140 104.356 -13.908 1.00 23.42 ? 64 GLY A O 1 ATOM 453 N N . PHE A 1 65 ? 46.465 102.900 -12.316 1.00 22.71 ? 65 PHE A N 1 ATOM 454 C CA . PHE A 1 65 ? 45.789 102.021 -13.277 1.00 23.24 ? 65 PHE A CA 1 ATOM 455 C C . PHE A 1 65 ? 44.791 101.078 -12.596 1.00 23.37 ? 65 PHE A C 1 ATOM 456 O O . PHE A 1 65 ? 44.861 100.847 -11.401 1.00 22.66 ? 65 PHE A O 1 ATOM 457 C CB . PHE A 1 65 ? 46.792 101.201 -14.110 1.00 23.50 ? 65 PHE A CB 1 ATOM 458 C CG . PHE A 1 65 ? 47.621 100.208 -13.287 1.00 24.73 ? 65 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 65 ? 47.135 98.939 -13.003 1.00 24.94 ? 65 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 65 ? 48.897 100.550 -12.837 1.00 25.34 ? 65 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 65 ? 47.884 98.031 -12.272 1.00 25.00 ? 65 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 65 ? 49.653 99.661 -12.110 1.00 25.42 ? 65 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 65 ? 49.137 98.396 -11.815 1.00 26.30 ? 65 PHE A CZ 1 ATOM 464 N N . THR A 1 66 ? 43.848 100.557 -13.378 1.00 24.05 ? 66 THR A N 1 ATOM 465 C CA . THR A 1 66 ? 42.910 99.515 -12.920 1.00 24.00 ? 66 THR A CA 1 ATOM 466 C C . THR A 1 66 ? 43.064 98.308 -13.841 1.00 24.23 ? 66 THR A C 1 ATOM 467 O O . THR A 1 66 ? 43.544 98.448 -14.981 1.00 24.27 ? 66 THR A O 1 ATOM 468 C CB . THR A 1 66 ? 41.430 100.021 -12.897 1.00 24.90 ? 66 THR A CB 1 ATOM 469 O OG1 . THR A 1 66 ? 41.048 100.479 -14.203 1.00 25.38 ? 66 THR A OG1 1 ATOM 470 C CG2 . THR A 1 66 ? 41.259 101.155 -11.889 1.00 23.94 ? 66 THR A CG2 1 ATOM 471 N N . ALA A 1 67 ? 42.718 97.122 -13.345 1.00 23.96 ? 67 ALA A N 1 ATOM 472 C CA . ALA A 1 67 ? 42.641 95.907 -14.144 1.00 24.96 ? 67 ALA A CA 1 ATOM 473 C C . ALA A 1 67 ? 41.429 95.106 -13.671 1.00 26.37 ? 67 ALA A C 1 ATOM 474 O O . ALA A 1 67 ? 41.105 95.124 -12.489 1.00 27.09 ? 67 ALA A O 1 ATOM 475 C CB . ALA A 1 67 ? 43.887 95.068 -13.987 1.00 24.36 ? 67 ALA A CB 1 ATOM 476 N N . ARG A 1 68 ? 40.777 94.406 -14.591 1.00 27.58 ? 68 ARG A N 1 ATOM 477 C CA . ARG A 1 68 ? 39.718 93.455 -14.255 1.00 29.24 ? 68 ARG A CA 1 ATOM 478 C C . ARG A 1 68 ? 40.338 92.077 -14.221 1.00 28.78 ? 68 ARG A C 1 ATOM 479 O O . ARG A 1 68 ? 41.062 91.682 -15.161 1.00 28.43 ? 68 ARG A O 1 ATOM 480 C CB . ARG A 1 68 ? 38.584 93.555 -15.276 1.00 30.65 ? 68 ARG A CB 1 ATOM 481 C CG . ARG A 1 68 ? 37.941 94.944 -15.267 1.00 35.56 ? 68 ARG A CG 1 ATOM 482 C CD . ARG A 1 68 ? 37.290 95.338 -16.610 1.00 46.18 ? 68 ARG A CD 1 ATOM 483 N NE . ARG A 1 68 ? 35.867 94.962 -16.683 1.00 53.62 ? 68 ARG A NE 1 ATOM 484 C CZ . ARG A 1 68 ? 34.838 95.785 -16.434 1.00 58.06 ? 68 ARG A CZ 1 ATOM 485 N NH1 . ARG A 1 68 ? 35.054 97.058 -16.091 1.00 58.58 ? 68 ARG A NH1 1 ATOM 486 N NH2 . ARG A 1 68 ? 33.577 95.333 -16.519 1.00 59.25 ? 68 ARG A NH2 1 ATOM 487 N N . LEU A 1 69 ? 40.140 91.377 -13.107 1.00 27.96 ? 69 LEU A N 1 ATOM 488 C CA . LEU A 1 69 ? 40.614 90.000 -12.974 1.00 28.82 ? 69 LEU A CA 1 ATOM 489 C C . LEU A 1 69 ? 39.388 89.086 -12.980 1.00 30.61 ? 69 LEU A C 1 ATOM 490 O O . LEU A 1 69 ? 38.362 89.428 -12.391 1.00 30.40 ? 69 LEU A O 1 ATOM 491 C CB . LEU A 1 69 ? 41.439 89.797 -11.694 1.00 28.07 ? 69 LEU A CB 1 ATOM 492 C CG . LEU A 1 69 ? 42.478 90.823 -11.196 1.00 26.96 ? 69 LEU A CG 1 ATOM 493 C CD1 . LEU A 1 69 ? 43.289 90.186 -10.086 1.00 25.45 ? 69 LEU A CD1 1 ATOM 494 C CD2 . LEU A 1 69 ? 43.379 91.310 -12.283 1.00 19.05 ? 69 LEU A CD2 1 ATOM 495 N N . LYS A 1 70 ? 39.486 87.957 -13.675 1.00 32.65 ? 70 LYS A N 1 ATOM 496 C CA . LYS A 1 70 ? 38.350 87.059 -13.836 1.00 34.95 ? 70 LYS A CA 1 ATOM 497 C C . LYS A 1 70 ? 38.767 85.717 -13.277 1.00 36.16 ? 70 LYS A C 1 ATOM 498 O O . LYS A 1 70 ? 39.876 85.252 -13.550 1.00 34.82 ? 70 LYS A O 1 ATOM 499 C CB . LYS A 1 70 ? 37.966 86.947 -15.309 1.00 35.17 ? 70 LYS A CB 1 ATOM 500 C CG . LYS A 1 70 ? 36.629 86.266 -15.598 1.00 38.93 ? 70 LYS A CG 1 ATOM 501 C CD . LYS A 1 70 ? 36.079 86.755 -16.967 1.00 43.46 ? 70 LYS A CD 1 ATOM 502 C CE . LYS A 1 70 ? 35.146 85.733 -17.659 1.00 44.20 ? 70 LYS A CE 1 ATOM 503 N NZ . LYS A 1 70 ? 34.842 86.111 -19.080 1.00 41.85 ? 70 LYS A NZ 1 ATOM 504 N N . ASN A 1 71 ? 37.885 85.108 -12.485 1.00 37.97 ? 71 ASN A N 1 ATOM 505 C CA . ASN A 1 71 ? 38.194 83.848 -11.797 1.00 41.27 ? 71 ASN A CA 1 ATOM 506 C C . ASN A 1 71 ? 38.338 82.632 -12.725 1.00 43.31 ? 71 ASN A C 1 ATOM 507 O O . ASN A 1 71 ? 37.440 82.326 -13.495 1.00 43.46 ? 71 ASN A O 1 ATOM 508 C CB . ASN A 1 71 ? 37.132 83.585 -10.713 1.00 41.25 ? 71 ASN A CB 1 ATOM 509 C CG . ASN A 1 71 ? 37.437 82.371 -9.848 1.00 42.90 ? 71 ASN A CG 1 ATOM 510 O OD1 . ASN A 1 71 ? 38.595 82.113 -9.464 1.00 44.45 ? 71 ASN A OD1 1 ATOM 511 N ND2 . ASN A 1 71 ? 36.380 81.618 -9.509 1.00 44.93 ? 71 ASN A ND2 1 ATOM 512 N N . LEU A 1 72 ? 39.473 81.944 -12.643 1.00 46.75 ? 72 LEU A N 1 ATOM 513 C CA . LEU A 1 72 ? 39.653 80.648 -13.328 1.00 50.13 ? 72 LEU A CA 1 ATOM 514 C C . LEU A 1 72 ? 38.926 79.534 -12.535 1.00 52.32 ? 72 LEU A C 1 ATOM 515 O O . LEU A 1 72 ? 39.400 79.132 -11.464 1.00 52.88 ? 72 LEU A O 1 ATOM 516 C CB . LEU A 1 72 ? 41.150 80.301 -13.459 1.00 50.09 ? 72 LEU A CB 1 ATOM 517 C CG . LEU A 1 72 ? 42.116 80.767 -14.573 1.00 50.60 ? 72 LEU A CG 1 ATOM 518 C CD1 . LEU A 1 72 ? 41.518 80.712 -15.997 1.00 51.48 ? 72 LEU A CD1 1 ATOM 519 C CD2 . LEU A 1 72 ? 42.689 82.109 -14.283 1.00 48.59 ? 72 LEU A CD2 1 ATOM 520 N N . PRO A 1 73 ? 37.777 79.031 -13.053 1.00 54.35 ? 73 PRO A N 1 ATOM 521 C CA . PRO A 1 73 ? 36.855 78.240 -12.210 1.00 55.28 ? 73 PRO A CA 1 ATOM 522 C C . PRO A 1 73 ? 37.477 77.015 -11.554 1.00 55.95 ? 73 PRO A C 1 ATOM 523 O O . PRO A 1 73 ? 38.385 76.391 -12.109 1.00 56.37 ? 73 PRO A O 1 ATOM 524 C CB . PRO A 1 73 ? 35.734 77.840 -13.184 1.00 55.40 ? 73 PRO A CB 1 ATOM 525 C CG . PRO A 1 73 ? 35.762 78.928 -14.229 1.00 55.29 ? 73 PRO A CG 1 ATOM 526 C CD . PRO A 1 73 ? 37.250 79.170 -14.428 1.00 54.83 ? 73 PRO A CD 1 ATOM 527 N N . SER A 1 74 ? 36.995 76.732 -10.349 1.00 56.66 ? 74 SER A N 1 ATOM 528 C CA . SER A 1 74 ? 37.411 75.604 -9.522 1.00 57.46 ? 74 SER A CA 1 ATOM 529 C C . SER A 1 74 ? 36.280 75.430 -8.526 1.00 57.60 ? 74 SER A C 1 ATOM 530 O O . SER A 1 74 ? 35.388 76.289 -8.439 1.00 57.88 ? 74 SER A O 1 ATOM 531 C CB . SER A 1 74 ? 38.723 75.882 -8.766 1.00 57.79 ? 74 SER A CB 1 ATOM 532 O OG . SER A 1 74 ? 39.875 75.784 -9.595 1.00 58.03 ? 74 SER A OG 1 ATOM 533 N N . SER A 1 75 ? 36.296 74.317 -7.792 1.00 57.49 ? 75 SER A N 1 ATOM 534 C CA . SER A 1 75 ? 35.239 74.047 -6.809 1.00 56.96 ? 75 SER A CA 1 ATOM 535 C C . SER A 1 75 ? 35.580 74.836 -5.539 1.00 56.07 ? 75 SER A C 1 ATOM 536 O O . SER A 1 75 ? 36.768 75.045 -5.242 1.00 56.28 ? 75 SER A O 1 ATOM 537 C CB . SER A 1 75 ? 35.073 72.530 -6.537 1.00 57.27 ? 75 SER A CB 1 ATOM 538 O OG . SER A 1 75 ? 34.543 71.826 -7.671 1.00 57.81 ? 75 SER A OG 1 ATOM 539 N N . PRO A 1 76 ? 34.547 75.337 -4.828 1.00 55.17 ? 76 PRO A N 1 ATOM 540 C CA . PRO A 1 76 ? 34.754 76.089 -3.592 1.00 54.26 ? 76 PRO A CA 1 ATOM 541 C C . PRO A 1 76 ? 35.561 75.313 -2.555 1.00 53.12 ? 76 PRO A C 1 ATOM 542 O O . PRO A 1 76 ? 35.290 74.130 -2.317 1.00 53.25 ? 76 PRO A O 1 ATOM 543 C CB . PRO A 1 76 ? 33.324 76.323 -3.092 1.00 54.36 ? 76 PRO A CB 1 ATOM 544 C CG . PRO A 1 76 ? 32.524 76.368 -4.337 1.00 54.89 ? 76 PRO A CG 1 ATOM 545 C CD . PRO A 1 76 ? 33.117 75.274 -5.169 1.00 55.02 ? 76 PRO A CD 1 ATOM 546 N N . VAL A 1 77 ? 36.569 75.975 -1.983 1.00 51.49 ? 77 VAL A N 1 ATOM 547 C CA . VAL A 1 77 ? 37.287 75.463 -0.820 1.00 49.32 ? 77 VAL A CA 1 ATOM 548 C C . VAL A 1 77 ? 36.525 75.974 0.416 1.00 47.53 ? 77 VAL A C 1 ATOM 549 O O . VAL A 1 77 ? 35.739 75.233 1.031 1.00 47.29 ? 77 VAL A O 1 ATOM 550 C CB . VAL A 1 77 ? 38.756 75.954 -0.809 1.00 49.49 ? 77 VAL A CB 1 ATOM 551 C CG1 . VAL A 1 77 ? 39.642 74.945 -0.123 1.00 49.95 ? 77 VAL A CG1 1 ATOM 552 C CG2 . VAL A 1 77 ? 39.265 76.195 -2.217 1.00 49.83 ? 77 VAL A CG2 1 ATOM 553 N N . PHE A 1 78 ? 36.735 77.255 0.740 1.00 44.85 ? 78 PHE A N 1 ATOM 554 C CA . PHE A 1 78 ? 36.033 77.941 1.831 1.00 42.86 ? 78 PHE A CA 1 ATOM 555 C C . PHE A 1 78 ? 35.193 79.035 1.205 1.00 42.36 ? 78 PHE A C 1 ATOM 556 O O . PHE A 1 78 ? 35.560 80.208 1.247 1.00 42.40 ? 78 PHE A O 1 ATOM 557 C CB . PHE A 1 78 ? 37.030 78.538 2.842 1.00 41.25 ? 78 PHE A CB 1 ATOM 558 C CG . PHE A 1 78 ? 38.164 77.618 3.186 1.00 38.09 ? 78 PHE A CG 1 ATOM 559 C CD1 . PHE A 1 78 ? 39.417 77.798 2.615 1.00 36.05 ? 78 PHE A CD1 1 ATOM 560 C CD2 . PHE A 1 78 ? 37.969 76.546 4.052 1.00 34.78 ? 78 PHE A CD2 1 ATOM 561 C CE1 . PHE A 1 78 ? 40.482 76.942 2.927 1.00 34.17 ? 78 PHE A CE1 1 ATOM 562 C CE2 . PHE A 1 78 ? 39.021 75.692 4.375 1.00 32.85 ? 78 PHE A CE2 1 ATOM 563 C CZ . PHE A 1 78 ? 40.280 75.888 3.808 1.00 35.12 ? 78 PHE A CZ 1 ATOM 564 N N . GLY A 1 79 ? 34.068 78.637 0.614 1.00 41.73 ? 79 GLY A N 1 ATOM 565 C CA . GLY A 1 79 ? 33.243 79.535 -0.199 1.00 40.99 ? 79 GLY A CA 1 ATOM 566 C C . GLY A 1 79 ? 33.833 79.586 -1.591 1.00 40.45 ? 79 GLY A C 1 ATOM 567 O O . GLY A 1 79 ? 34.967 79.141 -1.814 1.00 39.87 ? 79 GLY A O 1 ATOM 568 N N . SER A 1 80 ? 33.076 80.112 -2.546 1.00 40.05 ? 80 SER A N 1 ATOM 569 C CA . SER A 1 80 ? 33.600 80.168 -3.920 1.00 39.97 ? 80 SER A CA 1 ATOM 570 C C . SER A 1 80 ? 34.171 81.552 -4.234 1.00 39.04 ? 80 SER A C 1 ATOM 571 O O . SER A 1 80 ? 33.583 82.568 -3.840 1.00 38.08 ? 80 SER A O 1 ATOM 572 C CB . SER A 1 80 ? 32.552 79.729 -4.947 1.00 39.62 ? 80 SER A CB 1 ATOM 573 O OG . SER A 1 80 ? 31.359 80.427 -4.716 1.00 41.52 ? 80 SER A OG 1 ATOM 574 N N . ASN A 1 81 ? 35.333 81.580 -4.900 1.00 38.46 ? 81 ASN A N 1 ATOM 575 C CA . ASN A 1 81 ? 35.935 82.851 -5.279 1.00 38.42 ? 81 ASN A CA 1 ATOM 576 C C . ASN A 1 81 ? 34.884 83.739 -5.965 1.00 37.91 ? 81 ASN A C 1 ATOM 577 O O . ASN A 1 81 ? 34.070 83.270 -6.774 1.00 37.96 ? 81 ASN A O 1 ATOM 578 C CB . ASN A 1 81 ? 37.149 82.664 -6.192 1.00 38.81 ? 81 ASN A CB 1 ATOM 579 C CG . ASN A 1 81 ? 38.401 82.172 -5.451 1.00 40.66 ? 81 ASN A CG 1 ATOM 580 O OD1 . ASN A 1 81 ? 39.114 81.303 -5.953 1.00 45.60 ? 81 ASN A OD1 1 ATOM 581 N ND2 . ASN A 1 81 ? 38.674 82.721 -4.276 1.00 39.41 ? 81 ASN A ND2 1 ATOM 582 N N . VAL A 1 82 ? 34.873 85.003 -5.573 1.00 36.15 ? 82 VAL A N 1 ATOM 583 C CA . VAL A 1 82 ? 34.203 86.060 -6.281 1.00 34.99 ? 82 VAL A CA 1 ATOM 584 C C . VAL A 1 82 ? 34.585 86.002 -7.788 1.00 34.74 ? 82 VAL A C 1 ATOM 585 O O . VAL A 1 82 ? 35.761 85.842 -8.136 1.00 33.23 ? 82 VAL A O 1 ATOM 586 C CB . VAL A 1 82 ? 34.603 87.371 -5.569 1.00 35.59 ? 82 VAL A CB 1 ATOM 587 C CG1 . VAL A 1 82 ? 34.561 88.581 -6.464 1.00 34.01 ? 82 VAL A CG1 1 ATOM 588 C CG2 . VAL A 1 82 ? 33.768 87.550 -4.289 1.00 34.82 ? 82 VAL A CG2 1 ATOM 589 N N . ASP A 1 83 ? 33.580 86.099 -8.669 1.00 34.84 ? 83 ASP A N 1 ATOM 590 C CA . ASP A 1 83 ? 33.790 85.951 -10.129 1.00 35.19 ? 83 ASP A CA 1 ATOM 591 C C . ASP A 1 83 ? 34.691 87.036 -10.734 1.00 34.00 ? 83 ASP A C 1 ATOM 592 O O . ASP A 1 83 ? 35.564 86.748 -11.541 1.00 34.43 ? 83 ASP A O 1 ATOM 593 C CB . ASP A 1 83 ? 32.463 85.984 -10.889 1.00 35.75 ? 83 ASP A CB 1 ATOM 594 C CG . ASP A 1 83 ? 31.519 84.825 -10.522 1.00 41.06 ? 83 ASP A CG 1 ATOM 595 O OD1 . ASP A 1 83 ? 31.992 83.739 -10.071 1.00 43.31 ? 83 ASP A OD1 1 ATOM 596 O OD2 . ASP A 1 83 ? 30.289 85.018 -10.720 1.00 45.43 ? 83 ASP A OD2 1 ATOM 597 N N . ASN A 1 84 ? 34.425 88.282 -10.382 1.00 32.83 ? 84 ASN A N 1 ATOM 598 C CA . ASN A 1 84 ? 35.162 89.389 -10.948 1.00 33.06 ? 84 ASN A CA 1 ATOM 599 C C . ASN A 1 84 ? 35.772 90.284 -9.882 1.00 31.23 ? 84 ASN A C 1 ATOM 600 O O . ASN A 1 84 ? 35.063 90.879 -9.063 1.00 30.64 ? 84 ASN A O 1 ATOM 601 C CB . ASN A 1 84 ? 34.285 90.198 -11.895 1.00 33.89 ? 84 ASN A CB 1 ATOM 602 C CG . ASN A 1 84 ? 34.144 89.547 -13.236 1.00 36.98 ? 84 ASN A CG 1 ATOM 603 O OD1 . ASN A 1 84 ? 33.360 88.618 -13.399 1.00 39.77 ? 84 ASN A OD1 1 ATOM 604 N ND2 . ASN A 1 84 ? 34.926 90.016 -14.209 1.00 41.78 ? 84 ASN A ND2 1 ATOM 605 N N . VAL A 1 85 ? 37.094 90.360 -9.918 1.00 28.66 ? 85 VAL A N 1 ATOM 606 C CA . VAL A 1 85 ? 37.853 91.189 -8.983 1.00 26.81 ? 85 VAL A CA 1 ATOM 607 C C . VAL A 1 85 ? 38.400 92.461 -9.667 1.00 26.33 ? 85 VAL A C 1 ATOM 608 O O . VAL A 1 85 ? 38.846 92.413 -10.808 1.00 25.90 ? 85 VAL A O 1 ATOM 609 C CB . VAL A 1 85 ? 38.952 90.346 -8.285 1.00 26.36 ? 85 VAL A CB 1 ATOM 610 C CG1 . VAL A 1 85 ? 39.853 91.220 -7.411 1.00 21.87 ? 85 VAL A CG1 1 ATOM 611 C CG2 . VAL A 1 85 ? 38.270 89.266 -7.409 1.00 24.75 ? 85 VAL A CG2 1 ATOM 612 N N . LEU A 1 86 ? 38.298 93.602 -9.005 1.00 24.76 ? 86 LEU A N 1 ATOM 613 C CA . LEU A 1 86 ? 38.835 94.816 -9.587 1.00 24.76 ? 86 LEU A CA 1 ATOM 614 C C . LEU A 1 86 ? 40.149 95.138 -8.884 1.00 24.35 ? 86 LEU A C 1 ATOM 615 O O . LEU A 1 86 ? 40.188 95.255 -7.655 1.00 25.34 ? 86 LEU A O 1 ATOM 616 C CB . LEU A 1 86 ? 37.856 96.021 -9.498 1.00 23.34 ? 86 LEU A CB 1 ATOM 617 C CG . LEU A 1 86 ? 38.460 97.318 -10.077 1.00 24.32 ? 86 LEU A CG 1 ATOM 618 C CD1 . LEU A 1 86 ? 38.485 97.254 -11.606 1.00 24.97 ? 86 LEU A CD1 1 ATOM 619 C CD2 . LEU A 1 86 ? 37.795 98.610 -9.605 1.00 25.99 ? 86 LEU A CD2 1 ATOM 620 N N . LEU A 1 87 ? 41.214 95.289 -9.658 1.00 24.58 ? 87 LEU A N 1 ATOM 621 C CA . LEU A 1 87 ? 42.501 95.802 -9.120 1.00 24.23 ? 87 LEU A CA 1 ATOM 622 C C . LEU A 1 87 ? 42.647 97.300 -9.344 1.00 24.07 ? 87 LEU A C 1 ATOM 623 O O . LEU A 1 87 ? 42.753 97.717 -10.471 1.00 24.65 ? 87 LEU A O 1 ATOM 624 C CB . LEU A 1 87 ? 43.699 95.078 -9.772 1.00 24.60 ? 87 LEU A CB 1 ATOM 625 C CG . LEU A 1 87 ? 45.117 95.653 -9.512 1.00 24.23 ? 87 LEU A CG 1 ATOM 626 C CD1 . LEU A 1 87 ? 45.483 95.620 -8.023 1.00 22.75 ? 87 LEU A CD1 1 ATOM 627 C CD2 . LEU A 1 87 ? 46.140 94.846 -10.293 1.00 24.25 ? 87 LEU A CD2 1 ATOM 628 N N . THR A 1 88 ? 42.693 98.089 -8.273 1.00 23.97 ? 88 THR A N 1 ATOM 629 C CA . THR A 1 88 ? 42.955 99.521 -8.324 1.00 24.60 ? 88 THR A CA 1 ATOM 630 C C . THR A 1 88 ? 44.341 99.868 -7.745 1.00 24.66 ? 88 THR A C 1 ATOM 631 O O . THR A 1 88 ? 44.610 99.604 -6.578 1.00 24.84 ? 88 THR A O 1 ATOM 632 C CB . THR A 1 88 ? 41.909 100.313 -7.528 1.00 24.78 ? 88 THR A CB 1 ATOM 633 O OG1 . THR A 1 88 ? 40.605 99.970 -8.003 1.00 26.22 ? 88 THR A OG1 1 ATOM 634 C CG2 . THR A 1 88 ? 42.121 101.826 -7.703 1.00 26.06 ? 88 THR A CG2 1 ATOM 635 N N . ALA A 1 89 ? 45.188 100.470 -8.577 1.00 24.15 ? 89 ALA A N 1 ATOM 636 C CA . ALA A 1 89 ? 46.573 100.768 -8.240 1.00 23.79 ? 89 ALA A CA 1 ATOM 637 C C . ALA A 1 89 ? 46.810 102.275 -8.291 1.00 24.06 ? 89 ALA A C 1 ATOM 638 O O . ALA A 1 89 ? 46.499 102.926 -9.298 1.00 23.99 ? 89 ALA A O 1 ATOM 639 C CB . ALA A 1 89 ? 47.501 100.030 -9.186 1.00 22.74 ? 89 ALA A CB 1 ATOM 640 N N . GLU A 1 90 ? 47.275 102.848 -7.171 1.00 23.53 ? 90 GLU A N 1 ATOM 641 C CA . GLU A 1 90 ? 47.533 104.271 -7.096 1.00 23.11 ? 90 GLU A CA 1 ATOM 642 C C . GLU A 1 90 ? 49.005 104.514 -6.736 1.00 23.00 ? 90 GLU A C 1 ATOM 643 O O . GLU A 1 90 ? 49.521 103.946 -5.771 1.00 22.77 ? 90 GLU A O 1 ATOM 644 C CB . GLU A 1 90 ? 46.609 104.942 -6.071 1.00 22.94 ? 90 GLU A CB 1 ATOM 645 C CG . GLU A 1 90 ? 45.191 104.378 -6.054 1.00 24.32 ? 90 GLU A CG 1 ATOM 646 C CD . GLU A 1 90 ? 44.383 104.937 -4.914 1.00 26.06 ? 90 GLU A CD 1 ATOM 647 O OE1 . GLU A 1 90 ? 44.916 105.055 -3.779 1.00 26.00 ? 90 GLU A OE1 1 ATOM 648 O OE2 . GLU A 1 90 ? 43.212 105.285 -5.162 1.00 29.22 ? 90 GLU A OE2 1 ATOM 649 N N . TYR A 1 91 ? 49.673 105.343 -7.530 1.00 22.67 ? 91 TYR A N 1 ATOM 650 C CA . TYR A 1 91 ? 51.069 105.717 -7.277 1.00 22.58 ? 91 TYR A CA 1 ATOM 651 C C . TYR A 1 91 ? 51.045 106.961 -6.413 1.00 21.17 ? 91 TYR A C 1 ATOM 652 O O . TYR A 1 91 ? 51.194 108.076 -6.898 1.00 20.24 ? 91 TYR A O 1 ATOM 653 C CB . TYR A 1 91 ? 51.796 106.020 -8.600 1.00 23.60 ? 91 TYR A CB 1 ATOM 654 C CG . TYR A 1 91 ? 51.941 104.865 -9.577 1.00 24.41 ? 91 TYR A CG 1 ATOM 655 C CD1 . TYR A 1 91 ? 52.955 103.943 -9.449 1.00 27.64 ? 91 TYR A CD1 1 ATOM 656 C CD2 . TYR A 1 91 ? 51.112 104.750 -10.673 1.00 27.94 ? 91 TYR A CD2 1 ATOM 657 C CE1 . TYR A 1 91 ? 53.144 102.904 -10.377 1.00 26.91 ? 91 TYR A CE1 1 ATOM 658 C CE2 . TYR A 1 91 ? 51.256 103.685 -11.602 1.00 30.41 ? 91 TYR A CE2 1 ATOM 659 C CZ . TYR A 1 91 ? 52.281 102.770 -11.436 1.00 28.81 ? 91 TYR A CZ 1 ATOM 660 O OH . TYR A 1 91 ? 52.446 101.741 -12.324 1.00 27.52 ? 91 TYR A OH 1 ATOM 661 N N . GLN A 1 92 ? 50.844 106.771 -5.122 1.00 20.28 ? 92 GLN A N 1 ATOM 662 C CA . GLN A 1 92 ? 50.520 107.879 -4.227 1.00 20.36 ? 92 GLN A CA 1 ATOM 663 C C . GLN A 1 92 ? 51.655 108.870 -3.984 1.00 20.26 ? 92 GLN A C 1 ATOM 664 O O . GLN A 1 92 ? 51.421 110.080 -3.968 1.00 21.10 ? 92 GLN A O 1 ATOM 665 C CB . GLN A 1 92 ? 49.997 107.344 -2.899 1.00 19.72 ? 92 GLN A CB 1 ATOM 666 C CG . GLN A 1 92 ? 48.602 106.685 -3.049 1.00 21.06 ? 92 GLN A CG 1 ATOM 667 C CD . GLN A 1 92 ? 48.021 106.201 -1.735 1.00 21.49 ? 92 GLN A CD 1 ATOM 668 O OE1 . GLN A 1 92 ? 48.696 106.142 -0.707 1.00 22.20 ? 92 GLN A OE1 1 ATOM 669 N NE2 . GLN A 1 92 ? 46.760 105.882 -1.761 1.00 19.69 ? 92 GLN A NE2 1 ATOM 670 N N . THR A 1 93 ? 52.852 108.365 -3.740 1.00 19.56 ? 93 THR A N 1 ATOM 671 C CA . THR A 1 93 ? 54.044 109.213 -3.569 1.00 20.56 ? 93 THR A CA 1 ATOM 672 C C . THR A 1 93 ? 55.212 108.493 -4.259 1.00 20.05 ? 93 THR A C 1 ATOM 673 O O . THR A 1 93 ? 55.049 107.357 -4.717 1.00 18.54 ? 93 THR A O 1 ATOM 674 C CB . THR A 1 93 ? 54.366 109.560 -2.061 1.00 20.99 ? 93 THR A CB 1 ATOM 675 O OG1 . THR A 1 93 ? 55.033 108.474 -1.422 1.00 23.69 ? 93 THR A OG1 1 ATOM 676 C CG2 . THR A 1 93 ? 53.144 109.929 -1.246 1.00 21.21 ? 93 THR A CG2 1 ATOM 677 N N . SER A 1 94 ? 56.382 109.142 -4.345 1.00 20.50 ? 94 SER A N 1 ATOM 678 C CA . SER A 1 94 ? 57.606 108.494 -4.845 1.00 21.17 ? 94 SER A CA 1 ATOM 679 C C . SER A 1 94 ? 58.008 107.220 -4.121 1.00 20.60 ? 94 SER A C 1 ATOM 680 O O . SER A 1 94 ? 58.708 106.367 -4.688 1.00 20.63 ? 94 SER A O 1 ATOM 681 C CB . SER A 1 94 ? 58.796 109.493 -4.771 1.00 22.26 ? 94 SER A CB 1 ATOM 682 O OG . SER A 1 94 ? 58.393 110.726 -5.384 1.00 26.63 ? 94 SER A OG 1 ATOM 683 N N . ASN A 1 95 ? 57.613 107.112 -2.855 1.00 20.31 ? 95 ASN A N 1 ATOM 684 C CA . ASN A 1 95 ? 58.043 106.008 -1.986 1.00 20.88 ? 95 ASN A CA 1 ATOM 685 C C . ASN A 1 95 ? 56.877 105.149 -1.434 1.00 20.26 ? 95 ASN A C 1 ATOM 686 O O . ASN A 1 95 ? 57.086 104.240 -0.636 1.00 20.46 ? 95 ASN A O 1 ATOM 687 C CB . ASN A 1 95 ? 58.880 106.553 -0.819 1.00 20.87 ? 95 ASN A CB 1 ATOM 688 C CG . ASN A 1 95 ? 60.210 107.192 -1.299 1.00 25.08 ? 95 ASN A CG 1 ATOM 689 O OD1 . ASN A 1 95 ? 61.244 106.525 -1.394 1.00 31.99 ? 95 ASN A OD1 1 ATOM 690 N ND2 . ASN A 1 95 ? 60.164 108.455 -1.620 1.00 24.42 ? 95 ASN A ND2 1 ATOM 691 N N . ARG A 1 96 ? 55.658 105.451 -1.848 1.00 19.79 ? 96 ARG A N 1 ATOM 692 C CA . ARG A 1 96 ? 54.484 104.714 -1.364 1.00 19.38 ? 96 ARG A CA 1 ATOM 693 C C . ARG A 1 96 ? 53.584 104.330 -2.509 1.00 19.22 ? 96 ARG A C 1 ATOM 694 O O . ARG A 1 96 ? 53.080 105.200 -3.232 1.00 19.48 ? 96 ARG A O 1 ATOM 695 C CB . ARG A 1 96 ? 53.695 105.513 -0.335 1.00 19.31 ? 96 ARG A CB 1 ATOM 696 C CG . ARG A 1 96 ? 52.468 104.736 0.194 1.00 18.15 ? 96 ARG A CG 1 ATOM 697 C CD . ARG A 1 96 ? 51.779 105.484 1.332 1.00 21.26 ? 96 ARG A CD 1 ATOM 698 N NE . ARG A 1 96 ? 50.886 106.522 0.858 1.00 22.40 ? 96 ARG A NE 1 ATOM 699 C CZ . ARG A 1 96 ? 50.975 107.808 1.179 1.00 26.39 ? 96 ARG A CZ 1 ATOM 700 N NH1 . ARG A 1 96 ? 51.945 108.264 1.993 1.00 25.21 ? 96 ARG A NH1 1 ATOM 701 N NH2 . ARG A 1 96 ? 50.069 108.646 0.698 1.00 25.94 ? 96 ARG A NH2 1 ATOM 702 N N . PHE A 1 97 ? 53.426 103.016 -2.687 1.00 19.71 ? 97 PHE A N 1 ATOM 703 C CA . PHE A 1 97 ? 52.492 102.416 -3.662 1.00 19.26 ? 97 PHE A CA 1 ATOM 704 C C . PHE A 1 97 ? 51.286 101.818 -2.911 1.00 19.69 ? 97 PHE A C 1 ATOM 705 O O . PHE A 1 97 ? 51.460 101.139 -1.892 1.00 18.37 ? 97 PHE A O 1 ATOM 706 C CB . PHE A 1 97 ? 53.208 101.316 -4.472 1.00 18.90 ? 97 PHE A CB 1 ATOM 707 C CG . PHE A 1 97 ? 52.326 100.612 -5.503 1.00 19.35 ? 97 PHE A CG 1 ATOM 708 C CD1 . PHE A 1 97 ? 51.645 101.337 -6.494 1.00 18.30 ? 97 PHE A CD1 1 ATOM 709 C CD2 . PHE A 1 97 ? 52.207 99.226 -5.486 1.00 17.04 ? 97 PHE A CD2 1 ATOM 710 C CE1 . PHE A 1 97 ? 50.840 100.681 -7.426 1.00 19.49 ? 97 PHE A CE1 1 ATOM 711 C CE2 . PHE A 1 97 ? 51.431 98.568 -6.407 1.00 18.94 ? 97 PHE A CE2 1 ATOM 712 C CZ . PHE A 1 97 ? 50.731 99.293 -7.386 1.00 19.32 ? 97 PHE A CZ 1 ATOM 713 N N . HIS A 1 98 ? 50.091 102.083 -3.428 1.00 19.75 ? 98 HIS A N 1 ATOM 714 C CA . HIS A 1 98 ? 48.852 101.528 -2.891 1.00 21.00 ? 98 HIS A CA 1 ATOM 715 C C . HIS A 1 98 ? 48.152 100.665 -3.946 1.00 21.37 ? 98 HIS A C 1 ATOM 716 O O . HIS A 1 98 ? 47.926 101.117 -5.062 1.00 21.83 ? 98 HIS A O 1 ATOM 717 C CB . HIS A 1 98 ? 47.951 102.692 -2.456 1.00 20.46 ? 98 HIS A CB 1 ATOM 718 C CG . HIS A 1 98 ? 46.597 102.292 -1.953 1.00 22.37 ? 98 HIS A CG 1 ATOM 719 N ND1 . HIS A 1 98 ? 46.406 101.352 -0.959 1.00 23.72 ? 98 HIS A ND1 1 ATOM 720 C CD2 . HIS A 1 98 ? 45.367 102.762 -2.263 1.00 20.21 ? 98 HIS A CD2 1 ATOM 721 C CE1 . HIS A 1 98 ? 45.117 101.241 -0.700 1.00 19.17 ? 98 HIS A CE1 1 ATOM 722 N NE2 . HIS A 1 98 ? 44.465 102.083 -1.479 1.00 22.87 ? 98 HIS A NE2 1 ATOM 723 N N . PHE A 1 99 ? 47.827 99.418 -3.616 1.00 22.01 ? 99 PHE A N 1 ATOM 724 C CA . PHE A 1 99 ? 46.873 98.650 -4.445 1.00 22.02 ? 99 PHE A CA 1 ATOM 725 C C . PHE A 1 99 ? 45.758 97.978 -3.613 1.00 22.41 ? 99 PHE A C 1 ATOM 726 O O . PHE A 1 99 ? 46.014 97.468 -2.503 1.00 21.53 ? 99 PHE A O 1 ATOM 727 C CB . PHE A 1 99 ? 47.606 97.673 -5.393 1.00 21.57 ? 99 PHE A CB 1 ATOM 728 C CG . PHE A 1 99 ? 48.252 96.447 -4.706 1.00 22.96 ? 99 PHE A CG 1 ATOM 729 C CD1 . PHE A 1 99 ? 47.589 95.209 -4.663 1.00 22.46 ? 99 PHE A CD1 1 ATOM 730 C CD2 . PHE A 1 99 ? 49.541 96.512 -4.196 1.00 23.63 ? 99 PHE A CD2 1 ATOM 731 C CE1 . PHE A 1 99 ? 48.183 94.085 -4.057 1.00 20.38 ? 99 PHE A CE1 1 ATOM 732 C CE2 . PHE A 1 99 ? 50.145 95.378 -3.593 1.00 22.81 ? 99 PHE A CE2 1 ATOM 733 C CZ . PHE A 1 99 ? 49.461 94.177 -3.532 1.00 21.19 ? 99 PHE A CZ 1 ATOM 734 N N . LYS A 1 100 ? 44.530 97.999 -4.140 1.00 23.48 ? 100 LYS A N 1 ATOM 735 C CA . LYS A 1 100 ? 43.416 97.276 -3.531 1.00 24.71 ? 100 LYS A CA 1 ATOM 736 C C . LYS A 1 100 ? 42.676 96.372 -4.496 1.00 24.62 ? 100 LYS A C 1 ATOM 737 O O . LYS A 1 100 ? 42.536 96.688 -5.688 1.00 24.17 ? 100 LYS A O 1 ATOM 738 C CB . LYS A 1 100 ? 42.442 98.175 -2.730 1.00 25.13 ? 100 LYS A CB 1 ATOM 739 C CG . LYS A 1 100 ? 41.732 99.274 -3.409 1.00 27.52 ? 100 LYS A CG 1 ATOM 740 C CD . LYS A 1 100 ? 40.643 99.900 -2.502 1.00 27.29 ? 100 LYS A CD 1 ATOM 741 C CE . LYS A 1 100 ? 41.194 100.803 -1.369 1.00 32.29 ? 100 LYS A CE 1 ATOM 742 N NZ . LYS A 1 100 ? 40.152 101.587 -0.555 1.00 32.01 ? 100 LYS A NZ 1 ATOM 743 N N . LEU A 1 101 ? 42.235 95.232 -3.964 1.00 24.57 ? 101 LEU A N 1 ATOM 744 C CA . LEU A 1 101 ? 41.475 94.239 -4.720 1.00 25.20 ? 101 LEU A CA 1 ATOM 745 C C . LEU A 1 101 ? 40.078 94.176 -4.142 1.00 25.99 ? 101 LEU A C 1 ATOM 746 O O . LEU A 1 101 ? 39.902 93.906 -2.954 1.00 25.54 ? 101 LEU A O 1 ATOM 747 C CB . LEU A 1 101 ? 42.160 92.860 -4.671 1.00 24.78 ? 101 LEU A CB 1 ATOM 748 C CG . LEU A 1 101 ? 43.550 92.862 -5.329 1.00 25.42 ? 101 LEU A CG 1 ATOM 749 C CD1 . LEU A 1 101 ? 44.467 91.831 -4.662 1.00 23.74 ? 101 LEU A CD1 1 ATOM 750 C CD2 . LEU A 1 101 ? 43.451 92.659 -6.851 1.00 19.61 ? 101 LEU A CD2 1 ATOM 751 N N . THR A 1 102 ? 39.097 94.488 -4.977 1.00 26.29 ? 102 THR A N 1 ATOM 752 C CA . THR A 1 102 ? 37.724 94.566 -4.530 1.00 26.99 ? 102 THR A CA 1 ATOM 753 C C . THR A 1 102 ? 36.880 93.568 -5.350 1.00 28.44 ? 102 THR A C 1 ATOM 754 O O . THR A 1 102 ? 37.319 93.070 -6.386 1.00 28.14 ? 102 THR A O 1 ATOM 755 C CB . THR A 1 102 ? 37.140 95.992 -4.670 1.00 26.49 ? 102 THR A CB 1 ATOM 756 O OG1 . THR A 1 102 ? 37.431 96.514 -5.969 1.00 24.44 ? 102 THR A OG1 1 ATOM 757 C CG2 . THR A 1 102 ? 37.703 96.922 -3.620 1.00 27.29 ? 102 THR A CG2 1 ATOM 758 N N . ASP A 1 103 ? 35.695 93.254 -4.848 1.00 29.99 ? 103 ASP A N 1 ATOM 759 C CA . ASP A 1 103 ? 34.722 92.541 -5.620 1.00 32.19 ? 103 ASP A CA 1 ATOM 760 C C . ASP A 1 103 ? 34.172 93.569 -6.604 1.00 33.43 ? 103 ASP A C 1 ATOM 761 O O . ASP A 1 103 ? 33.610 94.588 -6.206 1.00 33.38 ? 103 ASP A O 1 ATOM 762 C CB . ASP A 1 103 ? 33.613 92.034 -4.696 1.00 32.14 ? 103 ASP A CB 1 ATOM 763 C CG . ASP A 1 103 ? 32.544 91.227 -5.428 1.00 34.65 ? 103 ASP A CG 1 ATOM 764 O OD1 . ASP A 1 103 ? 32.363 91.386 -6.666 1.00 36.39 ? 103 ASP A OD1 1 ATOM 765 O OD2 . ASP A 1 103 ? 31.870 90.430 -4.742 1.00 38.46 ? 103 ASP A OD2 1 ATOM 766 N N . GLN A 1 104 ? 34.336 93.293 -7.889 1.00 35.30 ? 104 GLN A N 1 ATOM 767 C CA . GLN A 1 104 ? 33.942 94.227 -8.938 1.00 37.55 ? 104 GLN A CA 1 ATOM 768 C C . GLN A 1 104 ? 32.443 94.536 -8.918 1.00 38.28 ? 104 GLN A C 1 ATOM 769 O O . GLN A 1 104 ? 32.031 95.631 -9.292 1.00 39.00 ? 104 GLN A O 1 ATOM 770 C CB . GLN A 1 104 ? 34.386 93.669 -10.289 1.00 38.02 ? 104 GLN A CB 1 ATOM 771 C CG . GLN A 1 104 ? 34.124 94.510 -11.513 1.00 41.28 ? 104 GLN A CG 1 ATOM 772 C CD . GLN A 1 104 ? 34.599 93.776 -12.741 1.00 44.77 ? 104 GLN A CD 1 ATOM 773 O OE1 . GLN A 1 104 ? 35.797 93.714 -12.991 1.00 47.52 ? 104 GLN A OE1 1 ATOM 774 N NE2 . GLN A 1 104 ? 33.669 93.171 -13.491 1.00 46.80 ? 104 GLN A NE2 1 ATOM 775 N N . THR A 1 105 ? 31.640 93.582 -8.454 1.00 39.24 ? 105 THR A N 1 ATOM 776 C CA . THR A 1 105 ? 30.184 93.739 -8.393 1.00 40.24 ? 105 THR A CA 1 ATOM 777 C C . THR A 1 105 ? 29.600 94.274 -7.065 1.00 40.33 ? 105 THR A C 1 ATOM 778 O O . THR A 1 105 ? 28.646 95.074 -7.087 1.00 40.71 ? 105 THR A O 1 ATOM 779 C CB . THR A 1 105 ? 29.467 92.415 -8.771 1.00 41.01 ? 105 THR A CB 1 ATOM 780 O OG1 . THR A 1 105 ? 30.159 91.781 -9.863 1.00 42.43 ? 105 THR A OG1 1 ATOM 781 C CG2 . THR A 1 105 ? 28.012 92.689 -9.166 1.00 41.07 ? 105 THR A CG2 1 ATOM 782 N N . ASN A 1 106 ? 30.146 93.845 -5.923 1.00 39.75 ? 106 ASN A N 1 ATOM 783 C CA . ASN A 1 106 ? 29.597 94.255 -4.607 1.00 39.63 ? 106 ASN A CA 1 ATOM 784 C C . ASN A 1 106 ? 30.576 95.029 -3.728 1.00 38.57 ? 106 ASN A C 1 ATOM 785 O O . ASN A 1 106 ? 31.788 94.776 -3.763 1.00 39.15 ? 106 ASN A O 1 ATOM 786 C CB . ASN A 1 106 ? 29.072 93.042 -3.829 1.00 39.58 ? 106 ASN A CB 1 ATOM 787 C CG . ASN A 1 106 ? 28.438 92.021 -4.738 1.00 41.82 ? 106 ASN A CG 1 ATOM 788 O OD1 . ASN A 1 106 ? 29.094 91.053 -5.149 1.00 43.97 ? 106 ASN A OD1 1 ATOM 789 N ND2 . ASN A 1 106 ? 27.165 92.246 -5.104 1.00 43.33 ? 106 ASN A ND2 1 ATOM 790 N N . ASN A 1 107 ? 30.039 95.971 -2.956 1.00 36.83 ? 107 ASN A N 1 ATOM 791 C CA . ASN A 1 107 ? 30.803 96.670 -1.938 1.00 35.33 ? 107 ASN A CA 1 ATOM 792 C C . ASN A 1 107 ? 31.063 95.653 -0.847 1.00 32.95 ? 107 ASN A C 1 ATOM 793 O O . ASN A 1 107 ? 30.224 94.803 -0.573 1.00 33.09 ? 107 ASN A O 1 ATOM 794 C CB . ASN A 1 107 ? 30.035 97.870 -1.365 1.00 36.46 ? 107 ASN A CB 1 ATOM 795 C CG . ASN A 1 107 ? 29.605 98.887 -2.443 1.00 39.75 ? 107 ASN A CG 1 ATOM 796 O OD1 . ASN A 1 107 ? 28.434 99.265 -2.500 1.00 46.68 ? 107 ASN A OD1 1 ATOM 797 N ND2 . ASN A 1 107 ? 30.545 99.339 -3.277 1.00 42.64 ? 107 ASN A ND2 1 ATOM 798 N N . ARG A 1 108 ? 32.248 95.711 -0.263 1.00 29.29 ? 108 ARG A N 1 ATOM 799 C CA . ARG A 1 108 ? 32.621 94.797 0.804 1.00 26.05 ? 108 ARG A CA 1 ATOM 800 C C . ARG A 1 108 ? 33.059 95.685 1.962 1.00 24.88 ? 108 ARG A C 1 ATOM 801 O O . ARG A 1 108 ? 33.245 96.898 1.775 1.00 23.93 ? 108 ARG A O 1 ATOM 802 C CB . ARG A 1 108 ? 33.740 93.833 0.341 1.00 26.04 ? 108 ARG A CB 1 ATOM 803 C CG . ARG A 1 108 ? 33.316 92.829 -0.752 1.00 24.22 ? 108 ARG A CG 1 ATOM 804 C CD . ARG A 1 108 ? 34.402 91.833 -1.113 1.00 22.95 ? 108 ARG A CD 1 ATOM 805 N NE . ARG A 1 108 ? 34.922 91.211 0.095 1.00 19.26 ? 108 ARG A NE 1 ATOM 806 C CZ . ARG A 1 108 ? 34.416 90.133 0.663 1.00 19.63 ? 108 ARG A CZ 1 ATOM 807 N NH1 . ARG A 1 108 ? 33.380 89.508 0.124 1.00 23.72 ? 108 ARG A NH1 1 ATOM 808 N NH2 . ARG A 1 108 ? 34.933 89.681 1.779 1.00 19.76 ? 108 ARG A NH2 1 ATOM 809 N N . PHE A 1 109 ? 33.174 95.100 3.158 1.00 24.03 ? 109 PHE A N 1 ATOM 810 C CA . PHE A 1 109 ? 33.641 95.854 4.316 1.00 23.21 ? 109 PHE A CA 1 ATOM 811 C C . PHE A 1 109 ? 35.064 96.404 4.079 1.00 22.80 ? 109 PHE A C 1 ATOM 812 O O . PHE A 1 109 ? 35.934 95.663 3.596 1.00 22.67 ? 109 PHE A O 1 ATOM 813 C CB . PHE A 1 109 ? 33.623 95.016 5.597 1.00 22.92 ? 109 PHE A CB 1 ATOM 814 C CG . PHE A 1 109 ? 34.252 95.724 6.756 1.00 21.66 ? 109 PHE A CG 1 ATOM 815 C CD1 . PHE A 1 109 ? 33.536 96.679 7.474 1.00 21.27 ? 109 PHE A CD1 1 ATOM 816 C CD2 . PHE A 1 109 ? 35.575 95.474 7.101 1.00 20.83 ? 109 PHE A CD2 1 ATOM 817 C CE1 . PHE A 1 109 ? 34.136 97.385 8.530 1.00 21.92 ? 109 PHE A CE1 1 ATOM 818 C CE2 . PHE A 1 109 ? 36.171 96.175 8.153 1.00 20.21 ? 109 PHE A CE2 1 ATOM 819 C CZ . PHE A 1 109 ? 35.450 97.120 8.860 1.00 20.97 ? 109 PHE A CZ 1 ATOM 820 N N . GLU A 1 110 ? 35.270 97.680 4.410 1.00 22.26 ? 110 GLU A N 1 ATOM 821 C CA . GLU A 1 110 ? 36.582 98.345 4.364 1.00 24.13 ? 110 GLU A CA 1 ATOM 822 C C . GLU A 1 110 ? 36.797 99.104 5.661 1.00 22.94 ? 110 GLU A C 1 ATOM 823 O O . GLU A 1 110 ? 35.865 99.755 6.165 1.00 22.63 ? 110 GLU A O 1 ATOM 824 C CB . GLU A 1 110 ? 36.672 99.286 3.161 1.00 23.69 ? 110 GLU A CB 1 ATOM 825 C CG . GLU A 1 110 ? 36.631 98.510 1.845 1.00 27.22 ? 110 GLU A CG 1 ATOM 826 C CD . GLU A 1 110 ? 36.869 99.350 0.597 1.00 29.35 ? 110 GLU A CD 1 ATOM 827 O OE1 . GLU A 1 110 ? 37.728 100.269 0.620 1.00 37.44 ? 110 GLU A OE1 1 ATOM 828 O OE2 . GLU A 1 110 ? 36.231 99.044 -0.441 1.00 35.12 ? 110 GLU A OE2 1 ATOM 829 N N . VAL A 1 111 ? 38.001 98.989 6.229 1.00 22.17 ? 111 VAL A N 1 ATOM 830 C CA . VAL A 1 111 ? 38.291 99.609 7.542 1.00 21.49 ? 111 VAL A CA 1 ATOM 831 C C . VAL A 1 111 ? 37.981 101.118 7.491 1.00 22.31 ? 111 VAL A C 1 ATOM 832 O O . VAL A 1 111 ? 38.483 101.781 6.614 1.00 22.33 ? 111 VAL A O 1 ATOM 833 C CB . VAL A 1 111 ? 39.743 99.348 7.959 1.00 20.70 ? 111 VAL A CB 1 ATOM 834 C CG1 . VAL A 1 111 ? 40.046 99.957 9.336 1.00 15.89 ? 111 VAL A CG1 1 ATOM 835 C CG2 . VAL A 1 111 ? 39.990 97.845 7.960 1.00 18.00 ? 111 VAL A CG2 1 ATOM 836 N N . PRO A 1 112 ? 37.094 101.637 8.380 1.00 23.07 ? 112 PRO A N 1 ATOM 837 C CA . PRO A 1 112 ? 36.859 103.076 8.409 1.00 23.56 ? 112 PRO A CA 1 ATOM 838 C C . PRO A 1 112 ? 37.904 103.791 9.276 1.00 24.21 ? 112 PRO A C 1 ATOM 839 O O . PRO A 1 112 ? 37.608 104.263 10.375 1.00 24.03 ? 112 PRO A O 1 ATOM 840 C CB . PRO A 1 112 ? 35.458 103.180 9.007 1.00 24.43 ? 112 PRO A CB 1 ATOM 841 C CG . PRO A 1 112 ? 35.369 102.023 9.929 1.00 23.74 ? 112 PRO A CG 1 ATOM 842 C CD . PRO A 1 112 ? 36.254 100.933 9.369 1.00 23.28 ? 112 PRO A CD 1 ATOM 843 N N . HIS A 1 113 ? 39.131 103.838 8.762 1.00 23.92 ? 113 HIS A N 1 ATOM 844 C CA . HIS A 1 113 ? 40.270 104.281 9.528 1.00 24.34 ? 113 HIS A CA 1 ATOM 845 C C . HIS A 1 113 ? 40.086 105.771 9.746 1.00 24.54 ? 113 HIS A C 1 ATOM 846 O O . HIS A 1 113 ? 39.600 106.458 8.858 1.00 24.04 ? 113 HIS A O 1 ATOM 847 C CB . HIS A 1 113 ? 41.583 103.997 8.778 1.00 23.33 ? 113 HIS A CB 1 ATOM 848 C CG . HIS A 1 113 ? 42.785 103.982 9.674 1.00 22.87 ? 113 HIS A CG 1 ATOM 849 N ND1 . HIS A 1 113 ? 43.662 105.043 9.770 1.00 20.61 ? 113 HIS A ND1 1 ATOM 850 C CD2 . HIS A 1 113 ? 43.221 103.053 10.558 1.00 20.78 ? 113 HIS A CD2 1 ATOM 851 C CE1 . HIS A 1 113 ? 44.597 104.759 10.656 1.00 20.07 ? 113 HIS A CE1 1 ATOM 852 N NE2 . HIS A 1 113 ? 44.343 103.563 11.160 1.00 19.62 ? 113 HIS A NE2 1 ATOM 853 N N . GLU A 1 114 ? 40.466 106.247 10.930 1.00 25.10 ? 114 GLU A N 1 ATOM 854 C CA . GLU A 1 114 ? 40.311 107.656 11.286 1.00 26.02 ? 114 GLU A CA 1 ATOM 855 C C . GLU A 1 114 ? 41.389 108.529 10.577 1.00 26.15 ? 114 GLU A C 1 ATOM 856 O O . GLU A 1 114 ? 41.118 109.690 10.219 1.00 26.35 ? 114 GLU A O 1 ATOM 857 C CB . GLU A 1 114 ? 40.344 107.807 12.816 1.00 26.88 ? 114 GLU A CB 1 ATOM 858 C CG . GLU A 1 114 ? 40.142 109.238 13.385 1.00 29.05 ? 114 GLU A CG 1 ATOM 859 C CD . GLU A 1 114 ? 41.420 110.097 13.300 1.00 32.03 ? 114 GLU A CD 1 ATOM 860 O OE1 . GLU A 1 114 ? 42.554 109.559 13.191 1.00 29.04 ? 114 GLU A OE1 1 ATOM 861 O OE2 . GLU A 1 114 ? 41.275 111.333 13.324 1.00 35.81 ? 114 GLU A OE2 1 ATOM 862 N N . HIS A 1 115 ? 42.574 107.988 10.318 1.00 24.28 ? 115 HIS A N 1 ATOM 863 C CA . HIS A 1 115 ? 43.627 108.859 9.763 1.00 24.17 ? 115 HIS A CA 1 ATOM 864 C C . HIS A 1 115 ? 43.765 108.776 8.239 1.00 24.19 ? 115 HIS A C 1 ATOM 865 O O . HIS A 1 115 ? 43.913 109.802 7.566 1.00 23.82 ? 115 HIS A O 1 ATOM 866 C CB . HIS A 1 115 ? 44.995 108.607 10.434 1.00 23.43 ? 115 HIS A CB 1 ATOM 867 C CG . HIS A 1 115 ? 46.027 109.637 10.090 1.00 24.45 ? 115 HIS A CG 1 ATOM 868 N ND1 . HIS A 1 115 ? 46.051 110.888 10.672 1.00 25.17 ? 115 HIS A ND1 1 ATOM 869 C CD2 . HIS A 1 115 ? 47.065 109.606 9.222 1.00 23.17 ? 115 HIS A CD2 1 ATOM 870 C CE1 . HIS A 1 115 ? 47.065 111.578 10.180 1.00 25.20 ? 115 HIS A CE1 1 ATOM 871 N NE2 . HIS A 1 115 ? 47.693 110.823 9.296 1.00 23.15 ? 115 HIS A NE2 1 ATOM 872 N N . VAL A 1 116 ? 43.744 107.562 7.702 1.00 24.57 ? 116 VAL A N 1 ATOM 873 C CA . VAL A 1 116 ? 44.006 107.385 6.294 1.00 26.53 ? 116 VAL A CA 1 ATOM 874 C C . VAL A 1 116 ? 42.863 108.020 5.486 1.00 28.29 ? 116 VAL A C 1 ATOM 875 O O . VAL A 1 116 ? 41.695 107.810 5.774 1.00 27.78 ? 116 VAL A O 1 ATOM 876 C CB . VAL A 1 116 ? 44.265 105.912 5.931 1.00 25.62 ? 116 VAL A CB 1 ATOM 877 C CG1 . VAL A 1 116 ? 44.362 105.739 4.418 1.00 24.46 ? 116 VAL A CG1 1 ATOM 878 C CG2 . VAL A 1 116 ? 45.557 105.430 6.633 1.00 24.90 ? 116 VAL A CG2 1 ATOM 879 N N . GLN A 1 117 ? 43.225 108.819 4.493 1.00 30.32 ? 117 GLN A N 1 ATOM 880 C CA . GLN A 1 117 ? 42.262 109.455 3.612 1.00 32.64 ? 117 GLN A CA 1 ATOM 881 C C . GLN A 1 117 ? 42.275 108.806 2.233 1.00 33.37 ? 117 GLN A C 1 ATOM 882 O O . GLN A 1 117 ? 43.317 108.301 1.784 1.00 33.30 ? 117 GLN A O 1 ATOM 883 C CB . GLN A 1 117 ? 42.615 110.923 3.480 1.00 33.55 ? 117 GLN A CB 1 ATOM 884 C CG . GLN A 1 117 ? 42.054 111.778 4.574 1.00 36.67 ? 117 GLN A CG 1 ATOM 885 C CD . GLN A 1 117 ? 41.870 113.199 4.084 1.00 43.30 ? 117 GLN A CD 1 ATOM 886 O OE1 . GLN A 1 117 ? 42.849 113.951 3.961 1.00 44.70 ? 117 GLN A OE1 1 ATOM 887 N NE2 . GLN A 1 117 ? 40.606 113.578 3.775 1.00 43.66 ? 117 GLN A NE2 1 ATOM 888 N N . SER A 1 118 ? 41.133 108.829 1.539 1.00 34.27 ? 118 SER A N 1 ATOM 889 C CA . SER A 1 118 ? 41.121 108.305 0.163 1.00 35.14 ? 118 SER A CA 1 ATOM 890 C C . SER A 1 118 ? 42.013 109.173 -0.714 1.00 34.88 ? 118 SER A C 1 ATOM 891 O O . SER A 1 118 ? 42.184 110.376 -0.461 1.00 34.19 ? 118 SER A O 1 ATOM 892 C CB . SER A 1 118 ? 39.709 108.160 -0.418 1.00 35.69 ? 118 SER A CB 1 ATOM 893 O OG . SER A 1 118 ? 39.084 109.427 -0.524 1.00 38.36 ? 118 SER A OG 1 ATOM 894 N N . PHE A 1 119 ? 42.624 108.539 -1.707 1.00 35.13 ? 119 PHE A N 1 ATOM 895 C CA . PHE A 1 119 ? 43.551 109.233 -2.587 1.00 35.81 ? 119 PHE A CA 1 ATOM 896 C C . PHE A 1 119 ? 42.805 109.843 -3.760 1.00 36.82 ? 119 PHE A C 1 ATOM 897 O O . PHE A 1 119 ? 41.980 109.201 -4.415 1.00 36.21 ? 119 PHE A O 1 ATOM 898 C CB . PHE A 1 119 ? 44.666 108.300 -3.066 1.00 34.86 ? 119 PHE A CB 1 ATOM 899 C CG . PHE A 1 119 ? 45.707 108.973 -3.900 1.00 33.81 ? 119 PHE A CG 1 ATOM 900 C CD1 . PHE A 1 119 ? 46.676 109.790 -3.317 1.00 35.38 ? 119 PHE A CD1 1 ATOM 901 C CD2 . PHE A 1 119 ? 45.747 108.778 -5.268 1.00 33.67 ? 119 PHE A CD2 1 ATOM 902 C CE1 . PHE A 1 119 ? 47.672 110.412 -4.109 1.00 33.53 ? 119 PHE A CE1 1 ATOM 903 C CE2 . PHE A 1 119 ? 46.731 109.400 -6.058 1.00 34.55 ? 119 PHE A CE2 1 ATOM 904 C CZ . PHE A 1 119 ? 47.684 110.220 -5.473 1.00 33.21 ? 119 PHE A CZ 1 ATOM 905 N N . SER A 1 120 ? 43.079 111.118 -3.976 1.00 38.35 ? 120 SER A N 1 ATOM 906 C CA . SER A 1 120 ? 42.659 111.813 -5.186 1.00 39.97 ? 120 SER A CA 1 ATOM 907 C C . SER A 1 120 ? 43.941 112.479 -5.705 1.00 40.13 ? 120 SER A C 1 ATOM 908 O O . SER A 1 120 ? 44.937 112.559 -4.989 1.00 41.01 ? 120 SER A O 1 ATOM 909 C CB . SER A 1 120 ? 41.583 112.847 -4.863 1.00 40.24 ? 120 SER A CB 1 ATOM 910 O OG . SER A 1 120 ? 42.004 113.652 -3.764 1.00 41.96 ? 120 SER A OG 1 ATOM 911 N N . GLY A 1 121 ? 43.941 112.928 -6.945 1.00 40.01 ? 121 GLY A N 1 ATOM 912 C CA . GLY A 1 121 ? 45.184 113.425 -7.520 1.00 39.02 ? 121 GLY A CA 1 ATOM 913 C C . GLY A 1 121 ? 45.869 112.413 -8.410 1.00 37.61 ? 121 GLY A C 1 ATOM 914 O O . GLY A 1 121 ? 45.367 111.312 -8.624 1.00 37.74 ? 121 GLY A O 1 ATOM 915 N N . ASN A 1 122 ? 47.026 112.804 -8.922 1.00 36.30 ? 122 ASN A N 1 ATOM 916 C CA . ASN A 1 122 ? 47.684 112.095 -10.004 1.00 35.43 ? 122 ASN A CA 1 ATOM 917 C C . ASN A 1 122 ? 48.875 111.310 -9.526 1.00 33.58 ? 122 ASN A C 1 ATOM 918 O O . ASN A 1 122 ? 49.453 111.636 -8.511 1.00 34.08 ? 122 ASN A O 1 ATOM 919 C CB . ASN A 1 122 ? 48.151 113.100 -11.068 1.00 35.67 ? 122 ASN A CB 1 ATOM 920 C CG . ASN A 1 122 ? 47.027 113.995 -11.560 1.00 37.96 ? 122 ASN A CG 1 ATOM 921 O OD1 . ASN A 1 122 ? 45.851 113.599 -11.589 1.00 40.00 ? 122 ASN A OD1 1 ATOM 922 N ND2 . ASN A 1 122 ? 47.383 115.218 -11.944 1.00 39.06 ? 122 ASN A ND2 1 ATOM 923 N N . ALA A 1 123 ? 49.245 110.295 -10.285 1.00 32.26 ? 123 ALA A N 1 ATOM 924 C CA . ALA A 1 123 ? 50.423 109.510 -10.028 1.00 31.59 ? 123 ALA A CA 1 ATOM 925 C C . ALA A 1 123 ? 51.594 110.432 -9.700 1.00 32.39 ? 123 ALA A C 1 ATOM 926 O O . ALA A 1 123 ? 51.817 111.449 -10.380 1.00 31.87 ? 123 ALA A O 1 ATOM 927 C CB . ALA A 1 123 ? 50.727 108.677 -11.233 1.00 31.30 ? 123 ALA A CB 1 ATOM 928 N N . ALA A 1 124 ? 52.329 110.105 -8.636 1.00 32.05 ? 124 ALA A N 1 ATOM 929 C CA . ALA A 1 124 ? 53.510 110.891 -8.242 1.00 31.53 ? 124 ALA A CA 1 ATOM 930 C C . ALA A 1 124 ? 54.578 110.842 -9.308 1.00 31.38 ? 124 ALA A C 1 ATOM 931 O O . ALA A 1 124 ? 54.699 109.869 -10.041 1.00 31.67 ? 124 ALA A O 1 ATOM 932 C CB . ALA A 1 124 ? 54.083 110.375 -6.957 1.00 30.83 ? 124 ALA A CB 1 ATOM 933 N N . ALA A 1 125 ? 55.386 111.892 -9.348 1.00 31.67 ? 125 ALA A N 1 ATOM 934 C CA . ALA A 1 125 ? 56.539 111.956 -10.218 1.00 31.65 ? 125 ALA A CA 1 ATOM 935 C C . ALA A 1 125 ? 57.728 111.345 -9.493 1.00 31.93 ? 125 ALA A C 1 ATOM 936 O O . ALA A 1 125 ? 57.693 111.155 -8.253 1.00 32.41 ? 125 ALA A O 1 ATOM 937 C CB . ALA A 1 125 ? 56.821 113.416 -10.572 1.00 31.63 ? 125 ALA A CB 1 ATOM 938 N N . SER A 1 126 ? 58.761 111.004 -10.265 1.00 31.22 ? 126 SER A N 1 ATOM 939 C CA . SER A 1 126 ? 60.015 110.491 -9.719 1.00 31.26 ? 126 SER A CA 1 ATOM 940 C C . SER A 1 126 ? 59.852 109.282 -8.782 1.00 30.35 ? 126 SER A C 1 ATOM 941 O O . SER A 1 126 ? 60.419 109.257 -7.671 1.00 30.73 ? 126 SER A O 1 ATOM 942 C CB . SER A 1 126 ? 60.789 111.619 -9.027 1.00 31.72 ? 126 SER A CB 1 ATOM 943 O OG . SER A 1 126 ? 61.107 112.633 -9.971 1.00 34.81 ? 126 SER A OG 1 ATOM 944 N N . LEU A 1 127 ? 59.090 108.281 -9.235 1.00 28.63 ? 127 LEU A N 1 ATOM 945 C CA . LEU A 1 127 ? 58.872 107.068 -8.445 1.00 26.85 ? 127 LEU A CA 1 ATOM 946 C C . LEU A 1 127 ? 60.197 106.341 -8.187 1.00 25.11 ? 127 LEU A C 1 ATOM 947 O O . LEU A 1 127 ? 61.062 106.289 -9.062 1.00 25.93 ? 127 LEU A O 1 ATOM 948 C CB . LEU A 1 127 ? 57.913 106.127 -9.178 1.00 26.97 ? 127 LEU A CB 1 ATOM 949 C CG . LEU A 1 127 ? 56.620 106.725 -9.714 1.00 26.41 ? 127 LEU A CG 1 ATOM 950 C CD1 . LEU A 1 127 ? 55.970 105.723 -10.625 1.00 27.64 ? 127 LEU A CD1 1 ATOM 951 C CD2 . LEU A 1 127 ? 55.729 107.133 -8.559 1.00 24.17 ? 127 LEU A CD2 1 ATOM 952 N N . THR A 1 128 ? 60.368 105.798 -6.991 1.00 22.98 ? 128 THR A N 1 ATOM 953 C CA . THR A 1 128 ? 61.540 104.989 -6.686 1.00 21.25 ? 128 THR A CA 1 ATOM 954 C C . THR A 1 128 ? 61.242 103.521 -6.971 1.00 21.62 ? 128 THR A C 1 ATOM 955 O O . THR A 1 128 ? 62.091 102.658 -6.771 1.00 21.80 ? 128 THR A O 1 ATOM 956 C CB . THR A 1 128 ? 61.971 105.144 -5.208 1.00 22.14 ? 128 THR A CB 1 ATOM 957 O OG1 . THR A 1 128 ? 60.886 104.778 -4.346 1.00 21.14 ? 128 THR A OG1 1 ATOM 958 C CG2 . THR A 1 128 ? 62.432 106.606 -4.895 1.00 22.72 ? 128 THR A CG2 1 ATOM 959 N N . TYR A 1 129 ? 60.016 103.219 -7.409 1.00 21.03 ? 129 TYR A N 1 ATOM 960 C CA . TYR A 1 129 ? 59.618 101.829 -7.636 1.00 21.38 ? 129 TYR A CA 1 ATOM 961 C C . TYR A 1 129 ? 58.963 101.712 -9.011 1.00 21.32 ? 129 TYR A C 1 ATOM 962 O O . TYR A 1 129 ? 58.519 102.702 -9.565 1.00 21.17 ? 129 TYR A O 1 ATOM 963 C CB . TYR A 1 129 ? 58.669 101.335 -6.528 1.00 19.58 ? 129 TYR A CB 1 ATOM 964 C CG . TYR A 1 129 ? 57.452 102.214 -6.379 1.00 20.91 ? 129 TYR A CG 1 ATOM 965 C CD1 . TYR A 1 129 ? 56.311 101.996 -7.156 1.00 19.98 ? 129 TYR A CD1 1 ATOM 966 C CD2 . TYR A 1 129 ? 57.446 103.294 -5.502 1.00 20.92 ? 129 TYR A CD2 1 ATOM 967 C CE1 . TYR A 1 129 ? 55.197 102.826 -7.052 1.00 20.50 ? 129 TYR A CE1 1 ATOM 968 C CE2 . TYR A 1 129 ? 56.334 104.147 -5.409 1.00 18.73 ? 129 TYR A CE2 1 ATOM 969 C CZ . TYR A 1 129 ? 55.206 103.889 -6.176 1.00 21.51 ? 129 TYR A CZ 1 ATOM 970 O OH . TYR A 1 129 ? 54.074 104.699 -6.071 1.00 19.67 ? 129 TYR A OH 1 ATOM 971 N N . GLN A 1 130 ? 58.927 100.504 -9.548 1.00 21.86 ? 130 GLN A N 1 ATOM 972 C CA . GLN A 1 130 ? 58.187 100.213 -10.748 1.00 23.72 ? 130 GLN A CA 1 ATOM 973 C C . GLN A 1 130 ? 57.195 99.053 -10.452 1.00 22.32 ? 130 GLN A C 1 ATOM 974 O O . GLN A 1 130 ? 57.518 98.159 -9.684 1.00 21.76 ? 130 GLN A O 1 ATOM 975 C CB . GLN A 1 130 ? 59.171 99.830 -11.861 1.00 22.79 ? 130 GLN A CB 1 ATOM 976 C CG . GLN A 1 130 ? 58.456 99.524 -13.184 1.00 27.88 ? 130 GLN A CG 1 ATOM 977 C CD . GLN A 1 130 ? 59.387 99.253 -14.347 1.00 30.23 ? 130 GLN A CD 1 ATOM 978 O OE1 . GLN A 1 130 ? 60.104 98.227 -14.384 1.00 36.58 ? 130 GLN A OE1 1 ATOM 979 N NE2 . GLN A 1 130 ? 59.379 100.170 -15.319 1.00 34.47 ? 130 GLN A NE2 1 ATOM 980 N N . VAL A 1 131 ? 56.031 99.051 -11.093 1.00 21.61 ? 131 VAL A N 1 ATOM 981 C CA . VAL A 1 131 ? 55.006 98.020 -10.864 1.00 22.19 ? 131 VAL A CA 1 ATOM 982 C C . VAL A 1 131 ? 54.764 97.192 -12.145 1.00 23.63 ? 131 VAL A C 1 ATOM 983 O O . VAL A 1 131 ? 54.587 97.746 -13.229 1.00 23.90 ? 131 VAL A O 1 ATOM 984 C CB . VAL A 1 131 ? 53.676 98.635 -10.355 1.00 22.54 ? 131 VAL A CB 1 ATOM 985 C CG1 . VAL A 1 131 ? 52.577 97.557 -10.171 1.00 22.15 ? 131 VAL A CG1 1 ATOM 986 C CG2 . VAL A 1 131 ? 53.884 99.395 -9.060 1.00 18.93 ? 131 VAL A CG2 1 ATOM 987 N N . GLU A 1 132 ? 54.799 95.865 -12.007 1.00 24.28 ? 132 GLU A N 1 ATOM 988 C CA A GLU A 1 132 ? 54.676 94.954 -13.134 0.50 24.91 ? 132 GLU A CA 1 ATOM 989 C CA B GLU A 1 132 ? 54.694 94.931 -13.137 0.50 24.91 ? 132 GLU A CA 1 ATOM 990 C C . GLU A 1 132 ? 53.510 94.012 -12.883 1.00 25.01 ? 132 GLU A C 1 ATOM 991 O O . GLU A 1 132 ? 53.390 93.442 -11.802 1.00 24.92 ? 132 GLU A O 1 ATOM 992 C CB A GLU A 1 132 ? 55.987 94.176 -13.279 0.50 24.79 ? 132 GLU A CB 1 ATOM 993 C CB B GLU A 1 132 ? 55.956 94.055 -13.256 0.50 24.69 ? 132 GLU A CB 1 ATOM 994 C CG A GLU A 1 132 ? 55.908 92.877 -14.023 0.50 26.24 ? 132 GLU A CG 1 ATOM 995 C CG B GLU A 1 132 ? 57.259 94.746 -13.706 0.50 26.40 ? 132 GLU A CG 1 ATOM 996 C CD A GLU A 1 132 ? 55.822 93.062 -15.513 0.50 28.07 ? 132 GLU A CD 1 ATOM 997 C CD B GLU A 1 132 ? 58.105 95.356 -12.566 0.50 26.59 ? 132 GLU A CD 1 ATOM 998 O OE1 A GLU A 1 132 ? 55.146 94.022 -15.978 0.50 28.76 ? 132 GLU A OE1 1 ATOM 999 O OE1 B GLU A 1 132 ? 57.773 95.211 -11.358 0.50 21.96 ? 132 GLU A OE1 1 ATOM 1000 O OE2 A GLU A 1 132 ? 56.420 92.226 -16.214 0.50 26.01 ? 132 GLU A OE2 1 ATOM 1001 O OE2 B GLU A 1 132 ? 59.133 95.999 -12.905 0.50 28.42 ? 132 GLU A OE2 1 ATOM 1002 N N . ILE A 1 133 ? 52.641 93.869 -13.873 1.00 26.08 ? 133 ILE A N 1 ATOM 1003 C CA . ILE A 1 133 ? 51.460 93.014 -13.773 1.00 26.08 ? 133 ILE A CA 1 ATOM 1004 C C . ILE A 1 133 ? 51.548 91.890 -14.808 1.00 27.53 ? 133 ILE A C 1 ATOM 1005 O O . ILE A 1 133 ? 51.739 92.150 -16.002 1.00 27.33 ? 133 ILE A O 1 ATOM 1006 C CB . ILE A 1 133 ? 50.161 93.829 -14.013 1.00 26.46 ? 133 ILE A CB 1 ATOM 1007 C CG1 . ILE A 1 133 ? 50.045 94.981 -12.987 1.00 26.89 ? 133 ILE A CG1 1 ATOM 1008 C CG2 . ILE A 1 133 ? 48.899 92.908 -14.030 1.00 23.12 ? 133 ILE A CG2 1 ATOM 1009 C CD1 . ILE A 1 133 ? 49.721 94.546 -11.560 1.00 26.10 ? 133 ILE A CD1 1 ATOM 1010 N N . SER A 1 134 ? 51.421 90.648 -14.345 1.00 28.37 ? 134 SER A N 1 ATOM 1011 C CA . SER A 1 134 ? 51.280 89.502 -15.226 1.00 29.24 ? 134 SER A CA 1 ATOM 1012 C C . SER A 1 134 ? 49.839 89.091 -15.363 1.00 29.55 ? 134 SER A C 1 ATOM 1013 O O . SER A 1 134 ? 49.022 89.221 -14.430 1.00 30.09 ? 134 SER A O 1 ATOM 1014 C CB . SER A 1 134 ? 52.071 88.321 -14.729 1.00 29.77 ? 134 SER A CB 1 ATOM 1015 O OG . SER A 1 134 ? 53.398 88.707 -14.620 1.00 31.78 ? 134 SER A OG 1 ATOM 1016 N N . ARG A 1 135 ? 49.562 88.567 -16.543 1.00 29.84 ? 135 ARG A N 1 ATOM 1017 C CA . ARG A 1 135 ? 48.225 88.372 -17.083 1.00 30.59 ? 135 ARG A CA 1 ATOM 1018 C C . ARG A 1 135 ? 47.699 86.986 -16.695 1.00 29.62 ? 135 ARG A C 1 ATOM 1019 O O . ARG A 1 135 ? 46.587 86.851 -16.163 1.00 27.63 ? 135 ARG A O 1 ATOM 1020 C CB . ARG A 1 135 ? 48.348 88.455 -18.649 1.00 33.46 ? 135 ARG A CB 1 ATOM 1021 C CG . ARG A 1 135 ? 47.796 89.694 -19.411 1.00 34.68 ? 135 ARG A CG 1 ATOM 1022 C CD . ARG A 1 135 ? 47.695 90.963 -18.522 1.00 38.66 ? 135 ARG A CD 1 ATOM 1023 N NE . ARG A 1 135 ? 47.459 92.151 -19.348 1.00 47.81 ? 135 ARG A NE 1 ATOM 1024 C CZ . ARG A 1 135 ? 46.382 92.383 -20.111 1.00 50.30 ? 135 ARG A CZ 1 ATOM 1025 N NH1 . ARG A 1 135 ? 45.357 91.512 -20.180 1.00 52.52 ? 135 ARG A NH1 1 ATOM 1026 N NH2 . ARG A 1 135 ? 46.337 93.495 -20.830 1.00 51.56 ? 135 ARG A NH2 1 ATOM 1027 N N . GLN A 1 136 ? 48.534 85.975 -16.962 1.00 28.98 ? 136 GLN A N 1 ATOM 1028 C CA . GLN A 1 136 ? 48.131 84.563 -17.014 1.00 30.28 ? 136 GLN A CA 1 ATOM 1029 C C . GLN A 1 136 ? 49.146 83.624 -16.337 1.00 29.19 ? 136 GLN A C 1 ATOM 1030 O O . GLN A 1 136 ? 50.100 83.154 -16.964 1.00 29.75 ? 136 GLN A O 1 ATOM 1031 C CB . GLN A 1 136 ? 47.859 84.112 -18.463 1.00 31.13 ? 136 GLN A CB 1 ATOM 1032 C CG . GLN A 1 136 ? 47.421 85.234 -19.472 1.00 36.10 ? 136 GLN A CG 1 ATOM 1033 C CD . GLN A 1 136 ? 45.917 85.538 -19.454 1.00 41.48 ? 136 GLN A CD 1 ATOM 1034 O OE1 . GLN A 1 136 ? 45.083 84.619 -19.491 1.00 45.80 ? 136 GLN A OE1 1 ATOM 1035 N NE2 . GLN A 1 136 ? 45.566 86.835 -19.437 1.00 39.99 ? 136 GLN A NE2 1 ATOM 1036 N N . PRO A 1 137 ? 48.953 83.358 -15.036 1.00 28.21 ? 137 PRO A N 1 ATOM 1037 C CA . PRO A 1 137 ? 47.844 83.871 -14.221 1.00 27.69 ? 137 PRO A CA 1 ATOM 1038 C C . PRO A 1 137 ? 48.169 85.254 -13.639 1.00 27.18 ? 137 PRO A C 1 ATOM 1039 O O . PRO A 1 137 ? 49.287 85.720 -13.791 1.00 26.83 ? 137 PRO A O 1 ATOM 1040 C CB . PRO A 1 137 ? 47.750 82.819 -13.122 1.00 27.91 ? 137 PRO A CB 1 ATOM 1041 C CG . PRO A 1 137 ? 49.183 82.396 -12.923 1.00 27.20 ? 137 PRO A CG 1 ATOM 1042 C CD . PRO A 1 137 ? 49.856 82.492 -14.260 1.00 28.00 ? 137 PRO A CD 1 ATOM 1043 N N . PHE A 1 138 ? 47.205 85.895 -12.997 1.00 26.25 ? 138 PHE A N 1 ATOM 1044 C CA . PHE A 1 138 ? 47.444 87.176 -12.367 1.00 26.22 ? 138 PHE A CA 1 ATOM 1045 C C . PHE A 1 138 ? 48.573 87.152 -11.324 1.00 26.50 ? 138 PHE A C 1 ATOM 1046 O O . PHE A 1 138 ? 48.614 86.281 -10.428 1.00 25.89 ? 138 PHE A O 1 ATOM 1047 C CB . PHE A 1 138 ? 46.183 87.751 -11.728 1.00 26.03 ? 138 PHE A CB 1 ATOM 1048 C CG . PHE A 1 138 ? 46.463 88.915 -10.795 1.00 27.26 ? 138 PHE A CG 1 ATOM 1049 C CD1 . PHE A 1 138 ? 46.522 88.722 -9.408 1.00 25.67 ? 138 PHE A CD1 1 ATOM 1050 C CD2 . PHE A 1 138 ? 46.714 90.190 -11.302 1.00 26.86 ? 138 PHE A CD2 1 ATOM 1051 C CE1 . PHE A 1 138 ? 46.819 89.762 -8.565 1.00 23.93 ? 138 PHE A CE1 1 ATOM 1052 C CE2 . PHE A 1 138 ? 47.010 91.251 -10.452 1.00 27.85 ? 138 PHE A CE2 1 ATOM 1053 C CZ . PHE A 1 138 ? 47.062 91.036 -9.083 1.00 25.95 ? 138 PHE A CZ 1 ATOM 1054 N N . SER A 1 139 ? 49.486 88.122 -11.461 1.00 25.58 ? 139 SER A N 1 ATOM 1055 C CA . SER A 1 139 ? 50.465 88.441 -10.421 1.00 25.05 ? 139 SER A CA 1 ATOM 1056 C C . SER A 1 139 ? 50.844 89.930 -10.426 1.00 24.52 ? 139 SER A C 1 ATOM 1057 O O . SER A 1 139 ? 50.695 90.638 -11.439 1.00 23.65 ? 139 SER A O 1 ATOM 1058 C CB . SER A 1 139 ? 51.692 87.504 -10.442 1.00 24.95 ? 139 SER A CB 1 ATOM 1059 O OG . SER A 1 139 ? 52.613 87.800 -11.476 1.00 28.02 ? 139 SER A OG 1 ATOM 1060 N N . ILE A 1 140 ? 51.268 90.413 -9.262 1.00 23.89 ? 140 ILE A N 1 ATOM 1061 C CA . ILE A 1 140 ? 51.673 91.797 -9.112 1.00 23.32 ? 140 ILE A CA 1 ATOM 1062 C C . ILE A 1 140 ? 53.065 91.839 -8.522 1.00 24.07 ? 140 ILE A C 1 ATOM 1063 O O . ILE A 1 140 ? 53.360 91.124 -7.552 1.00 23.13 ? 140 ILE A O 1 ATOM 1064 C CB . ILE A 1 140 ? 50.677 92.658 -8.282 1.00 23.33 ? 140 ILE A CB 1 ATOM 1065 C CG1 . ILE A 1 140 ? 51.171 94.106 -8.204 1.00 23.35 ? 140 ILE A CG1 1 ATOM 1066 C CG2 . ILE A 1 140 ? 50.427 92.083 -6.852 1.00 21.89 ? 140 ILE A CG2 1 ATOM 1067 C CD1 . ILE A 1 140 ? 50.036 95.112 -8.001 1.00 24.16 ? 140 ILE A CD1 1 ATOM 1068 N N . LYS A 1 141 ? 53.911 92.670 -9.125 1.00 24.00 ? 141 LYS A N 1 ATOM 1069 C CA . LYS A 1 141 ? 55.307 92.781 -8.717 1.00 25.71 ? 141 LYS A CA 1 ATOM 1070 C C . LYS A 1 141 ? 55.669 94.271 -8.523 1.00 24.42 ? 141 LYS A C 1 ATOM 1071 O O . LYS A 1 141 ? 55.256 95.119 -9.313 1.00 24.62 ? 141 LYS A O 1 ATOM 1072 C CB . LYS A 1 141 ? 56.170 92.095 -9.778 1.00 25.37 ? 141 LYS A CB 1 ATOM 1073 C CG . LYS A 1 141 ? 57.632 91.957 -9.469 1.00 29.29 ? 141 LYS A CG 1 ATOM 1074 C CD . LYS A 1 141 ? 58.445 91.570 -10.741 1.00 29.44 ? 141 LYS A CD 1 ATOM 1075 C CE . LYS A 1 141 ? 58.114 90.156 -11.255 1.00 37.65 ? 141 LYS A CE 1 ATOM 1076 N NZ . LYS A 1 141 ? 59.195 89.675 -12.218 1.00 41.03 ? 141 LYS A NZ 1 ATOM 1077 N N . VAL A 1 142 ? 56.356 94.584 -7.431 1.00 22.62 ? 142 VAL A N 1 ATOM 1078 C CA . VAL A 1 142 ? 56.862 95.938 -7.154 1.00 21.28 ? 142 VAL A CA 1 ATOM 1079 C C . VAL A 1 142 ? 58.367 95.811 -7.039 1.00 21.47 ? 142 VAL A C 1 ATOM 1080 O O . VAL A 1 142 ? 58.863 95.041 -6.214 1.00 21.54 ? 142 VAL A O 1 ATOM 1081 C CB . VAL A 1 142 ? 56.270 96.561 -5.856 1.00 20.65 ? 142 VAL A CB 1 ATOM 1082 C CG1 . VAL A 1 142 ? 56.877 97.929 -5.578 1.00 19.65 ? 142 VAL A CG1 1 ATOM 1083 C CG2 . VAL A 1 142 ? 54.744 96.684 -5.977 1.00 19.94 ? 142 VAL A CG2 1 ATOM 1084 N N . THR A 1 143 ? 59.097 96.518 -7.899 1.00 21.42 ? 143 THR A N 1 ATOM 1085 C CA . THR A 1 143 ? 60.539 96.408 -7.866 1.00 21.99 ? 143 THR A CA 1 ATOM 1086 C C . THR A 1 143 ? 61.176 97.775 -7.589 1.00 21.41 ? 143 THR A C 1 ATOM 1087 O O . THR A 1 143 ? 60.626 98.828 -7.923 1.00 22.29 ? 143 THR A O 1 ATOM 1088 C CB . THR A 1 143 ? 61.114 95.725 -9.156 1.00 22.44 ? 143 THR A CB 1 ATOM 1089 O OG1 . THR A 1 143 ? 61.103 96.659 -10.219 1.00 26.23 ? 143 THR A OG1 1 ATOM 1090 C CG2 . THR A 1 143 ? 60.264 94.542 -9.579 1.00 20.41 ? 143 THR A CG2 1 ATOM 1091 N N . ARG A 1 144 ? 62.351 97.761 -6.995 1.00 20.48 ? 144 ARG A N 1 ATOM 1092 C CA . ARG A 1 144 ? 63.057 99.001 -6.710 1.00 19.30 ? 144 ARG A CA 1 ATOM 1093 C C . ARG A 1 144 ? 63.713 99.461 -8.031 1.00 20.12 ? 144 ARG A C 1 ATOM 1094 O O . ARG A 1 144 ? 64.460 98.715 -8.641 1.00 19.50 ? 144 ARG A O 1 ATOM 1095 C CB . ARG A 1 144 ? 64.094 98.741 -5.617 1.00 17.89 ? 144 ARG A CB 1 ATOM 1096 C CG . ARG A 1 144 ? 64.919 99.963 -5.205 1.00 17.97 ? 144 ARG A CG 1 ATOM 1097 C CD . ARG A 1 144 ? 65.872 99.631 -4.084 1.00 17.51 ? 144 ARG A CD 1 ATOM 1098 N NE . ARG A 1 144 ? 65.190 99.542 -2.804 1.00 18.40 ? 144 ARG A NE 1 ATOM 1099 C CZ . ARG A 1 144 ? 64.768 100.586 -2.090 1.00 18.05 ? 144 ARG A CZ 1 ATOM 1100 N NH1 . ARG A 1 144 ? 64.933 101.846 -2.512 1.00 18.19 ? 144 ARG A NH1 1 ATOM 1101 N NH2 . ARG A 1 144 ? 64.179 100.367 -0.932 1.00 16.24 ? 144 ARG A NH2 1 ATOM 1102 N N . ARG A 1 145 ? 63.413 100.667 -8.477 1.00 21.07 ? 145 ARG A N 1 ATOM 1103 C CA . ARG A 1 145 ? 63.943 101.148 -9.763 1.00 23.76 ? 145 ARG A CA 1 ATOM 1104 C C . ARG A 1 145 ? 65.465 101.140 -9.891 1.00 23.74 ? 145 ARG A C 1 ATOM 1105 O O . ARG A 1 145 ? 65.978 100.808 -10.953 1.00 25.15 ? 145 ARG A O 1 ATOM 1106 C CB . ARG A 1 145 ? 63.473 102.570 -10.049 1.00 23.66 ? 145 ARG A CB 1 ATOM 1107 C CG . ARG A 1 145 ? 62.681 102.708 -11.294 1.00 30.69 ? 145 ARG A CG 1 ATOM 1108 C CD . ARG A 1 145 ? 62.128 104.104 -11.477 1.00 37.84 ? 145 ARG A CD 1 ATOM 1109 N NE . ARG A 1 145 ? 63.138 104.952 -12.098 1.00 45.26 ? 145 ARG A NE 1 ATOM 1110 C CZ . ARG A 1 145 ? 63.049 106.271 -12.243 1.00 48.63 ? 145 ARG A CZ 1 ATOM 1111 N NH1 . ARG A 1 145 ? 61.985 106.940 -11.790 1.00 49.29 ? 145 ARG A NH1 1 ATOM 1112 N NH2 . ARG A 1 145 ? 64.043 106.925 -12.842 1.00 51.18 ? 145 ARG A NH2 1 ATOM 1113 N N . SER A 1 146 ? 66.175 101.536 -8.836 1.00 23.80 ? 146 SER A N 1 ATOM 1114 C CA . SER A 1 146 ? 67.604 101.823 -8.966 1.00 25.26 ? 146 SER A CA 1 ATOM 1115 C C . SER A 1 146 ? 68.433 100.569 -9.182 1.00 25.20 ? 146 SER A C 1 ATOM 1116 O O . SER A 1 146 ? 69.440 100.583 -9.933 1.00 26.89 ? 146 SER A O 1 ATOM 1117 C CB . SER A 1 146 ? 68.136 102.574 -7.733 1.00 25.68 ? 146 SER A CB 1 ATOM 1118 O OG . SER A 1 146 ? 67.982 101.807 -6.535 1.00 25.54 ? 146 SER A OG 1 ATOM 1119 N N . ASN A 1 147 ? 68.043 99.489 -8.516 1.00 23.08 ? 147 ASN A N 1 ATOM 1120 C CA . ASN A 1 147 ? 68.737 98.234 -8.703 1.00 21.70 ? 147 ASN A CA 1 ATOM 1121 C C . ASN A 1 147 ? 67.850 97.088 -9.262 1.00 20.89 ? 147 ASN A C 1 ATOM 1122 O O . ASN A 1 147 ? 68.287 95.969 -9.351 1.00 21.17 ? 147 ASN A O 1 ATOM 1123 C CB . ASN A 1 147 ? 69.481 97.830 -7.419 1.00 21.24 ? 147 ASN A CB 1 ATOM 1124 C CG . ASN A 1 147 ? 68.567 97.675 -6.222 1.00 21.85 ? 147 ASN A CG 1 ATOM 1125 O OD1 . ASN A 1 147 ? 67.356 97.852 -6.318 1.00 21.36 ? 147 ASN A OD1 1 ATOM 1126 N ND2 . ASN A 1 147 ? 69.143 97.337 -5.089 1.00 16.84 ? 147 ASN A ND2 1 ATOM 1127 N N . ASN A 1 148 ? 66.617 97.387 -9.648 1.00 20.28 ? 148 ASN A N 1 ATOM 1128 C CA . ASN A 1 148 ? 65.634 96.341 -10.042 1.00 20.00 ? 148 ASN A CA 1 ATOM 1129 C C . ASN A 1 148 ? 65.426 95.193 -9.022 1.00 19.87 ? 148 ASN A C 1 ATOM 1130 O O . ASN A 1 148 ? 65.050 94.074 -9.406 1.00 19.45 ? 148 ASN A O 1 ATOM 1131 C CB . ASN A 1 148 ? 65.975 95.771 -11.439 1.00 20.54 ? 148 ASN A CB 1 ATOM 1132 C CG . ASN A 1 148 ? 65.775 96.792 -12.541 1.00 21.03 ? 148 ASN A CG 1 ATOM 1133 O OD1 . ASN A 1 148 ? 66.293 96.644 -13.646 1.00 26.18 ? 148 ASN A OD1 1 ATOM 1134 N ND2 . ASN A 1 148 ? 64.988 97.811 -12.259 1.00 19.76 ? 148 ASN A ND2 1 ATOM 1135 N N . ARG A 1 149 ? 65.666 95.473 -7.745 1.00 19.10 ? 149 ARG A N 1 ATOM 1136 C CA . ARG A 1 149 ? 65.438 94.483 -6.686 1.00 19.84 ? 149 ARG A CA 1 ATOM 1137 C C . ARG A 1 149 ? 63.937 94.228 -6.628 1.00 19.77 ? 149 ARG A C 1 ATOM 1138 O O . ARG A 1 149 ? 63.146 95.163 -6.489 1.00 18.41 ? 149 ARG A O 1 ATOM 1139 C CB . ARG A 1 149 ? 65.898 95.003 -5.333 1.00 19.93 ? 149 ARG A CB 1 ATOM 1140 C CG . ARG A 1 149 ? 65.723 94.040 -4.173 1.00 23.19 ? 149 ARG A CG 1 ATOM 1141 C CD . ARG A 1 149 ? 66.893 93.048 -4.108 1.00 25.05 ? 149 ARG A CD 1 ATOM 1142 N NE . ARG A 1 149 ? 68.084 93.675 -3.541 1.00 29.72 ? 149 ARG A NE 1 ATOM 1143 C CZ . ARG A 1 149 ? 69.306 93.151 -3.643 1.00 33.92 ? 149 ARG A CZ 1 ATOM 1144 N NH1 . ARG A 1 149 ? 69.488 91.999 -4.300 1.00 33.51 ? 149 ARG A NH1 1 ATOM 1145 N NH2 . ARG A 1 149 ? 70.347 93.773 -3.103 1.00 32.20 ? 149 ARG A NH2 1 ATOM 1146 N N . VAL A 1 150 ? 63.562 92.963 -6.767 1.00 19.21 ? 150 VAL A N 1 ATOM 1147 C CA . VAL A 1 150 ? 62.190 92.590 -6.613 1.00 19.92 ? 150 VAL A CA 1 ATOM 1148 C C . VAL A 1 150 ? 61.832 92.616 -5.131 1.00 19.27 ? 150 VAL A C 1 ATOM 1149 O O . VAL A 1 150 ? 62.406 91.865 -4.329 1.00 17.32 ? 150 VAL A O 1 ATOM 1150 C CB . VAL A 1 150 ? 61.889 91.220 -7.246 1.00 20.68 ? 150 VAL A CB 1 ATOM 1151 C CG1 . VAL A 1 150 ? 60.355 90.913 -7.109 1.00 19.80 ? 150 VAL A CG1 1 ATOM 1152 C CG2 . VAL A 1 150 ? 62.312 91.240 -8.715 1.00 21.37 ? 150 VAL A CG2 1 ATOM 1153 N N . LEU A 1 151 ? 60.878 93.482 -4.791 1.00 18.81 ? 151 LEU A N 1 ATOM 1154 C CA . LEU A 1 151 ? 60.462 93.673 -3.395 1.00 18.70 ? 151 LEU A CA 1 ATOM 1155 C C . LEU A 1 151 ? 59.185 92.859 -3.020 1.00 19.60 ? 151 LEU A C 1 ATOM 1156 O O . LEU A 1 151 ? 59.228 91.994 -2.149 1.00 19.21 ? 151 LEU A O 1 ATOM 1157 C CB . LEU A 1 151 ? 60.243 95.172 -3.134 1.00 17.81 ? 151 LEU A CB 1 ATOM 1158 C CG . LEU A 1 151 ? 61.441 96.070 -3.507 1.00 17.52 ? 151 LEU A CG 1 ATOM 1159 C CD1 . LEU A 1 151 ? 61.195 97.466 -3.041 1.00 13.78 ? 151 LEU A CD1 1 ATOM 1160 C CD2 . LEU A 1 151 ? 62.673 95.523 -2.825 1.00 12.90 ? 151 LEU A CD2 1 ATOM 1161 N N . PHE A 1 152 ? 58.069 93.197 -3.662 1.00 19.86 ? 152 PHE A N 1 ATOM 1162 C CA . PHE A 1 152 ? 56.778 92.497 -3.534 1.00 21.10 ? 152 PHE A CA 1 ATOM 1163 C C . PHE A 1 152 ? 56.682 91.686 -4.826 1.00 21.77 ? 152 PHE A C 1 ATOM 1164 O O . PHE A 1 152 ? 56.932 92.226 -5.893 1.00 21.15 ? 152 PHE A O 1 ATOM 1165 C CB . PHE A 1 152 ? 55.606 93.507 -3.509 1.00 20.69 ? 152 PHE A CB 1 ATOM 1166 C CG . PHE A 1 152 ? 54.297 92.937 -2.951 1.00 22.72 ? 152 PHE A CG 1 ATOM 1167 C CD1 . PHE A 1 152 ? 53.959 93.113 -1.602 1.00 20.24 ? 152 PHE A CD1 1 ATOM 1168 C CD2 . PHE A 1 152 ? 53.422 92.202 -3.767 1.00 24.12 ? 152 PHE A CD2 1 ATOM 1169 C CE1 . PHE A 1 152 ? 52.741 92.595 -1.075 1.00 22.90 ? 152 PHE A CE1 1 ATOM 1170 C CE2 . PHE A 1 152 ? 52.221 91.644 -3.230 1.00 22.79 ? 152 PHE A CE2 1 ATOM 1171 C CZ . PHE A 1 152 ? 51.896 91.835 -1.880 1.00 20.93 ? 152 PHE A CZ 1 ATOM 1172 N N . ASP A 1 153 ? 56.333 90.407 -4.737 1.00 22.36 ? 153 ASP A N 1 ATOM 1173 C CA . ASP A 1 153 ? 56.063 89.602 -5.920 1.00 22.68 ? 153 ASP A CA 1 ATOM 1174 C C . ASP A 1 153 ? 55.039 88.507 -5.594 1.00 21.83 ? 153 ASP A C 1 ATOM 1175 O O . ASP A 1 153 ? 55.387 87.491 -5.020 1.00 22.58 ? 153 ASP A O 1 ATOM 1176 C CB . ASP A 1 153 ? 57.352 88.967 -6.450 1.00 23.53 ? 153 ASP A CB 1 ATOM 1177 C CG . ASP A 1 153 ? 57.089 88.022 -7.625 1.00 26.98 ? 153 ASP A CG 1 ATOM 1178 O OD1 . ASP A 1 153 ? 55.927 87.957 -8.116 1.00 29.43 ? 153 ASP A OD1 1 ATOM 1179 O OD2 . ASP A 1 153 ? 58.032 87.328 -8.055 1.00 31.27 ? 153 ASP A OD2 1 ATOM 1180 N N . SER A 1 154 ? 53.790 88.704 -5.975 1.00 21.04 ? 154 SER A N 1 ATOM 1181 C CA . SER A 1 154 ? 52.740 87.745 -5.634 1.00 21.41 ? 154 SER A CA 1 ATOM 1182 C C . SER A 1 154 ? 52.764 86.445 -6.433 1.00 21.29 ? 154 SER A C 1 ATOM 1183 O O . SER A 1 154 ? 52.012 85.521 -6.122 1.00 21.39 ? 154 SER A O 1 ATOM 1184 C CB . SER A 1 154 ? 51.363 88.422 -5.715 1.00 20.46 ? 154 SER A CB 1 ATOM 1185 O OG . SER A 1 154 ? 50.909 88.495 -7.060 1.00 21.17 ? 154 SER A OG 1 ATOM 1186 N N . SER A 1 155 ? 53.651 86.338 -7.429 1.00 23.31 ? 155 SER A N 1 ATOM 1187 C CA . SER A 1 155 ? 53.629 85.191 -8.389 1.00 22.97 ? 155 SER A CA 1 ATOM 1188 C C . SER A 1 155 ? 53.945 83.853 -7.743 1.00 22.31 ? 155 SER A C 1 ATOM 1189 O O . SER A 1 155 ? 53.785 82.814 -8.365 1.00 22.54 ? 155 SER A O 1 ATOM 1190 C CB . SER A 1 155 ? 54.570 85.437 -9.592 1.00 23.45 ? 155 SER A CB 1 ATOM 1191 O OG . SER A 1 155 ? 55.927 85.188 -9.225 1.00 24.93 ? 155 SER A OG 1 ATOM 1192 N N . ILE A 1 156 ? 54.398 83.863 -6.494 1.00 21.44 ? 156 ILE A N 1 ATOM 1193 C CA . ILE A 1 156 ? 54.637 82.601 -5.784 1.00 20.88 ? 156 ILE A CA 1 ATOM 1194 C C . ILE A 1 156 ? 53.328 81.811 -5.508 1.00 21.19 ? 156 ILE A C 1 ATOM 1195 O O . ILE A 1 156 ? 53.354 80.607 -5.389 1.00 19.90 ? 156 ILE A O 1 ATOM 1196 C CB . ILE A 1 156 ? 55.479 82.802 -4.475 1.00 20.80 ? 156 ILE A CB 1 ATOM 1197 C CG1 . ILE A 1 156 ? 55.976 81.471 -3.907 1.00 21.55 ? 156 ILE A CG1 1 ATOM 1198 C CG2 . ILE A 1 156 ? 54.749 83.681 -3.435 1.00 19.63 ? 156 ILE A CG2 1 ATOM 1199 C CD1 . ILE A 1 156 ? 57.084 81.658 -2.855 1.00 21.35 ? 156 ILE A CD1 1 ATOM 1200 N N . GLY A 1 157 ? 52.194 82.492 -5.452 1.00 20.83 ? 157 GLY A N 1 ATOM 1201 C CA . GLY A 1 157 ? 50.960 81.828 -5.034 1.00 21.01 ? 157 GLY A CA 1 ATOM 1202 C C . GLY A 1 157 ? 49.792 82.428 -5.750 1.00 21.16 ? 157 GLY A C 1 ATOM 1203 O O . GLY A 1 157 ? 49.963 83.385 -6.518 1.00 20.32 ? 157 GLY A O 1 ATOM 1204 N N . PRO A 1 158 ? 48.581 81.876 -5.498 1.00 21.64 ? 158 PRO A N 1 ATOM 1205 C CA . PRO A 1 158 ? 47.373 82.397 -6.111 1.00 21.38 ? 158 PRO A CA 1 ATOM 1206 C C . PRO A 1 158 ? 46.883 83.668 -5.409 1.00 21.33 ? 158 PRO A C 1 ATOM 1207 O O . PRO A 1 158 ? 47.344 83.993 -4.329 1.00 22.35 ? 158 PRO A O 1 ATOM 1208 C CB . PRO A 1 158 ? 46.357 81.262 -5.888 1.00 21.39 ? 158 PRO A CB 1 ATOM 1209 C CG . PRO A 1 158 ? 46.798 80.623 -4.620 1.00 22.12 ? 158 PRO A CG 1 ATOM 1210 C CD . PRO A 1 158 ? 48.306 80.759 -4.567 1.00 21.76 ? 158 PRO A CD 1 ATOM 1211 N N . LEU A 1 159 ? 45.962 84.378 -6.042 1.00 20.83 ? 159 LEU A N 1 ATOM 1212 C CA . LEU A 1 159 ? 45.113 85.315 -5.369 1.00 21.11 ? 159 LEU A CA 1 ATOM 1213 C C . LEU A 1 159 ? 43.877 84.464 -5.057 1.00 21.64 ? 159 LEU A C 1 ATOM 1214 O O . LEU A 1 159 ? 43.359 83.792 -5.953 1.00 22.14 ? 159 LEU A O 1 ATOM 1215 C CB . LEU A 1 159 ? 44.734 86.465 -6.311 1.00 20.87 ? 159 LEU A CB 1 ATOM 1216 C CG . LEU A 1 159 ? 43.483 87.293 -5.958 1.00 20.95 ? 159 LEU A CG 1 ATOM 1217 C CD1 . LEU A 1 159 ? 43.565 88.023 -4.620 1.00 18.69 ? 159 LEU A CD1 1 ATOM 1218 C CD2 . LEU A 1 159 ? 43.168 88.278 -7.030 1.00 20.73 ? 159 LEU A CD2 1 ATOM 1219 N N . LEU A 1 160 ? 43.434 84.439 -3.803 1.00 21.70 ? 160 LEU A N 1 ATOM 1220 C CA . LEU A 1 160 ? 42.167 83.759 -3.446 1.00 21.93 ? 160 LEU A CA 1 ATOM 1221 C C . LEU A 1 160 ? 41.296 84.866 -2.900 1.00 22.05 ? 160 LEU A C 1 ATOM 1222 O O . LEU A 1 160 ? 41.783 85.750 -2.183 1.00 21.18 ? 160 LEU A O 1 ATOM 1223 C CB . LEU A 1 160 ? 42.403 82.646 -2.423 1.00 21.71 ? 160 LEU A CB 1 ATOM 1224 C CG . LEU A 1 160 ? 43.490 81.683 -2.922 1.00 22.95 ? 160 LEU A CG 1 ATOM 1225 C CD1 . LEU A 1 160 ? 43.954 80.782 -1.837 1.00 23.78 ? 160 LEU A CD1 1 ATOM 1226 C CD2 . LEU A 1 160 ? 43.048 80.861 -4.154 1.00 22.84 ? 160 LEU A CD2 1 ATOM 1227 N N . PHE A 1 161 ? 40.027 84.864 -3.285 1.00 22.54 ? 161 PHE A N 1 ATOM 1228 C CA . PHE A 1 161 ? 39.116 85.951 -2.961 1.00 23.45 ? 161 PHE A CA 1 ATOM 1229 C C . PHE A 1 161 ? 37.699 85.352 -2.865 1.00 23.91 ? 161 PHE A C 1 ATOM 1230 O O . PHE A 1 161 ? 36.911 85.532 -3.795 1.00 24.43 ? 161 PHE A O 1 ATOM 1231 C CB . PHE A 1 161 ? 39.190 87.027 -4.078 1.00 23.88 ? 161 PHE A CB 1 ATOM 1232 C CG . PHE A 1 161 ? 38.852 88.422 -3.623 1.00 25.38 ? 161 PHE A CG 1 ATOM 1233 C CD1 . PHE A 1 161 ? 39.858 89.378 -3.451 1.00 28.91 ? 161 PHE A CD1 1 ATOM 1234 C CD2 . PHE A 1 161 ? 37.552 88.785 -3.330 1.00 28.72 ? 161 PHE A CD2 1 ATOM 1235 C CE1 . PHE A 1 161 ? 39.554 90.677 -2.998 1.00 30.12 ? 161 PHE A CE1 1 ATOM 1236 C CE2 . PHE A 1 161 ? 37.237 90.075 -2.887 1.00 27.83 ? 161 PHE A CE2 1 ATOM 1237 C CZ . PHE A 1 161 ? 38.233 91.016 -2.737 1.00 28.03 ? 161 PHE A CZ 1 ATOM 1238 N N . ALA A 1 162 ? 37.394 84.622 -1.785 1.00 23.02 ? 162 ALA A N 1 ATOM 1239 C CA . ALA A 1 162 ? 35.987 84.233 -1.453 1.00 23.65 ? 162 ALA A CA 1 ATOM 1240 C C . ALA A 1 162 ? 35.450 85.144 -0.329 1.00 23.57 ? 162 ALA A C 1 ATOM 1241 O O . ALA A 1 162 ? 36.239 85.865 0.294 1.00 23.61 ? 162 ALA A O 1 ATOM 1242 C CB . ALA A 1 162 ? 35.893 82.760 -1.047 1.00 23.27 ? 162 ALA A CB 1 ATOM 1243 N N . ASP A 1 163 ? 34.140 85.125 -0.067 1.00 22.63 ? 163 ASP A N 1 ATOM 1244 C CA . ASP A 1 163 ? 33.532 86.070 0.872 1.00 23.00 ? 163 ASP A CA 1 ATOM 1245 C C . ASP A 1 163 ? 34.224 86.022 2.237 1.00 22.20 ? 163 ASP A C 1 ATOM 1246 O O . ASP A 1 163 ? 34.358 87.043 2.895 1.00 22.67 ? 163 ASP A O 1 ATOM 1247 C CB . ASP A 1 163 ? 32.026 85.791 1.011 1.00 24.60 ? 163 ASP A CB 1 ATOM 1248 C CG . ASP A 1 163 ? 31.283 86.848 1.841 1.00 29.20 ? 163 ASP A CG 1 ATOM 1249 O OD1 . ASP A 1 163 ? 31.547 88.076 1.664 1.00 32.16 ? 163 ASP A OD1 1 ATOM 1250 O OD2 . ASP A 1 163 ? 30.404 86.440 2.665 1.00 32.56 ? 163 ASP A OD2 1 ATOM 1251 N N . GLN A 1 164 ? 34.693 84.842 2.640 1.00 21.23 ? 164 GLN A N 1 ATOM 1252 C CA . GLN A 1 164 ? 35.254 84.635 3.973 1.00 20.16 ? 164 GLN A CA 1 ATOM 1253 C C . GLN A 1 164 ? 36.589 83.915 3.919 1.00 19.66 ? 164 GLN A C 1 ATOM 1254 O O . GLN A 1 164 ? 36.964 83.195 4.865 1.00 19.84 ? 164 GLN A O 1 ATOM 1255 C CB . GLN A 1 164 ? 34.244 83.837 4.846 1.00 20.28 ? 164 GLN A CB 1 ATOM 1256 C CG . GLN A 1 164 ? 33.005 84.621 5.151 1.00 19.36 ? 164 GLN A CG 1 ATOM 1257 C CD . GLN A 1 164 ? 32.086 83.883 6.079 1.00 22.81 ? 164 GLN A CD 1 ATOM 1258 O OE1 . GLN A 1 164 ? 32.285 83.861 7.310 1.00 22.90 ? 164 GLN A OE1 1 ATOM 1259 N NE2 . GLN A 1 164 ? 31.070 83.263 5.503 1.00 20.69 ? 164 GLN A NE2 1 ATOM 1260 N N . PHE A 1 165 ? 37.303 84.094 2.817 1.00 19.63 ? 165 PHE A N 1 ATOM 1261 C CA . PHE A 1 165 ? 38.631 83.539 2.665 1.00 20.14 ? 165 PHE A CA 1 ATOM 1262 C C . PHE A 1 165 ? 39.371 84.234 1.527 1.00 20.23 ? 165 PHE A C 1 ATOM 1263 O O . PHE A 1 165 ? 39.046 84.038 0.347 1.00 20.03 ? 165 PHE A O 1 ATOM 1264 C CB . PHE A 1 165 ? 38.620 82.023 2.444 1.00 20.24 ? 165 PHE A CB 1 ATOM 1265 C CG . PHE A 1 165 ? 39.977 81.393 2.581 1.00 21.18 ? 165 PHE A CG 1 ATOM 1266 C CD1 . PHE A 1 165 ? 40.423 80.941 3.812 1.00 21.53 ? 165 PHE A CD1 1 ATOM 1267 C CD2 . PHE A 1 165 ? 40.829 81.289 1.474 1.00 23.55 ? 165 PHE A CD2 1 ATOM 1268 C CE1 . PHE A 1 165 ? 41.678 80.351 3.939 1.00 22.62 ? 165 PHE A CE1 1 ATOM 1269 C CE2 . PHE A 1 165 ? 42.078 80.712 1.583 1.00 22.87 ? 165 PHE A CE2 1 ATOM 1270 C CZ . PHE A 1 165 ? 42.510 80.236 2.825 1.00 24.11 ? 165 PHE A CZ 1 ATOM 1271 N N . LEU A 1 166 ? 40.340 85.080 1.911 1.00 19.21 ? 166 LEU A N 1 ATOM 1272 C CA . LEU A 1 166 ? 41.083 85.918 0.971 1.00 18.49 ? 166 LEU A CA 1 ATOM 1273 C C . LEU A 1 166 ? 42.541 85.698 1.262 1.00 18.22 ? 166 LEU A C 1 ATOM 1274 O O . LEU A 1 166 ? 42.940 85.665 2.415 1.00 19.25 ? 166 LEU A O 1 ATOM 1275 C CB . LEU A 1 166 ? 40.745 87.398 1.114 1.00 17.10 ? 166 LEU A CB 1 ATOM 1276 C CG . LEU A 1 166 ? 39.314 87.851 0.856 1.00 20.38 ? 166 LEU A CG 1 ATOM 1277 C CD1 . LEU A 1 166 ? 38.492 87.763 2.133 1.00 18.07 ? 166 LEU A CD1 1 ATOM 1278 C CD2 . LEU A 1 166 ? 39.367 89.272 0.393 1.00 18.59 ? 166 LEU A CD2 1 ATOM 1279 N N . GLN A 1 167 ? 43.342 85.513 0.229 1.00 18.24 ? 167 GLN A N 1 ATOM 1280 C CA . GLN A 1 167 ? 44.738 85.231 0.444 1.00 17.79 ? 167 GLN A CA 1 ATOM 1281 C C . GLN A 1 167 ? 45.560 85.828 -0.701 1.00 18.03 ? 167 GLN A C 1 ATOM 1282 O O . GLN A 1 167 ? 45.131 85.763 -1.852 1.00 17.20 ? 167 GLN A O 1 ATOM 1283 C CB . GLN A 1 167 ? 44.948 83.717 0.511 1.00 17.98 ? 167 GLN A CB 1 ATOM 1284 C CG . GLN A 1 167 ? 46.345 83.282 0.922 1.00 17.37 ? 167 GLN A CG 1 ATOM 1285 C CD . GLN A 1 167 ? 46.510 81.776 1.077 1.00 18.81 ? 167 GLN A CD 1 ATOM 1286 O OE1 . GLN A 1 167 ? 47.248 81.139 0.331 1.00 25.91 ? 167 GLN A OE1 1 ATOM 1287 N NE2 . GLN A 1 167 ? 45.837 81.211 2.023 1.00 22.37 ? 167 GLN A NE2 1 ATOM 1288 N N . LEU A 1 168 ? 46.740 86.376 -0.371 1.00 17.25 ? 168 LEU A N 1 ATOM 1289 C CA . LEU A 1 168 ? 47.753 86.828 -1.334 1.00 17.41 ? 168 LEU A CA 1 ATOM 1290 C C . LEU A 1 168 ? 49.126 86.625 -0.683 1.00 18.09 ? 168 LEU A C 1 ATOM 1291 O O . LEU A 1 168 ? 49.260 86.860 0.504 1.00 18.18 ? 168 LEU A O 1 ATOM 1292 C CB . LEU A 1 168 ? 47.563 88.299 -1.739 1.00 16.95 ? 168 LEU A CB 1 ATOM 1293 C CG . LEU A 1 168 ? 48.302 88.788 -3.014 1.00 17.71 ? 168 LEU A CG 1 ATOM 1294 C CD1 . LEU A 1 168 ? 47.728 88.171 -4.323 1.00 14.86 ? 168 LEU A CD1 1 ATOM 1295 C CD2 . LEU A 1 168 ? 48.248 90.295 -3.039 1.00 18.33 ? 168 LEU A CD2 1 ATOM 1296 N N . SER A 1 169 ? 50.094 86.096 -1.436 1.00 18.34 ? 169 SER A N 1 ATOM 1297 C CA . SER A 1 169 ? 51.470 85.859 -0.948 1.00 19.07 ? 169 SER A CA 1 ATOM 1298 C C . SER A 1 169 ? 52.428 86.853 -1.616 1.00 19.73 ? 169 SER A C 1 ATOM 1299 O O . SER A 1 169 ? 52.035 87.533 -2.568 1.00 19.19 ? 169 SER A O 1 ATOM 1300 C CB . SER A 1 169 ? 51.945 84.456 -1.290 1.00 19.35 ? 169 SER A CB 1 ATOM 1301 O OG . SER A 1 169 ? 50.960 83.490 -0.998 1.00 20.01 ? 169 SER A OG 1 ATOM 1302 N N . THR A 1 170 ? 53.638 87.001 -1.069 1.00 19.11 ? 170 THR A N 1 ATOM 1303 C CA . THR A 1 170 ? 54.713 87.700 -1.775 1.00 20.13 ? 170 THR A CA 1 ATOM 1304 C C . THR A 1 170 ? 56.073 87.084 -1.471 1.00 19.34 ? 170 THR A C 1 ATOM 1305 O O . THR A 1 170 ? 56.351 86.758 -0.322 1.00 19.07 ? 170 THR A O 1 ATOM 1306 C CB . THR A 1 170 ? 54.779 89.243 -1.438 1.00 20.56 ? 170 THR A CB 1 ATOM 1307 O OG1 . THR A 1 170 ? 55.999 89.780 -1.953 1.00 19.51 ? 170 THR A OG1 1 ATOM 1308 C CG2 . THR A 1 170 ? 54.765 89.535 0.079 1.00 21.28 ? 170 THR A CG2 1 ATOM 1309 N N . ARG A 1 171 ? 56.932 86.936 -2.475 1.00 19.97 ? 171 ARG A N 1 ATOM 1310 C CA . ARG A 1 171 ? 58.316 86.571 -2.198 1.00 20.36 ? 171 ARG A CA 1 ATOM 1311 C C . ARG A 1 171 ? 58.926 87.765 -1.497 1.00 20.10 ? 171 ARG A C 1 ATOM 1312 O O . ARG A 1 171 ? 58.396 88.889 -1.586 1.00 19.81 ? 171 ARG A O 1 ATOM 1313 C CB . ARG A 1 171 ? 59.111 86.326 -3.496 1.00 20.59 ? 171 ARG A CB 1 ATOM 1314 C CG . ARG A 1 171 ? 58.668 85.124 -4.291 1.00 22.47 ? 171 ARG A CG 1 ATOM 1315 C CD . ARG A 1 171 ? 59.519 84.965 -5.567 1.00 24.07 ? 171 ARG A CD 1 ATOM 1316 N NE . ARG A 1 171 ? 58.634 84.588 -6.659 1.00 30.12 ? 171 ARG A NE 1 ATOM 1317 C CZ . ARG A 1 171 ? 58.408 83.347 -7.059 1.00 30.74 ? 171 ARG A CZ 1 ATOM 1318 N NH1 . ARG A 1 171 ? 59.045 82.337 -6.488 1.00 29.63 ? 171 ARG A NH1 1 ATOM 1319 N NH2 . ARG A 1 171 ? 57.532 83.137 -8.035 1.00 31.58 ? 171 ARG A NH2 1 ATOM 1320 N N . LEU A 1 172 ? 60.046 87.526 -0.831 1.00 20.04 ? 172 LEU A N 1 ATOM 1321 C CA . LEU A 1 172 ? 60.791 88.560 -0.128 1.00 20.86 ? 172 LEU A CA 1 ATOM 1322 C C . LEU A 1 172 ? 62.236 88.499 -0.617 1.00 20.90 ? 172 LEU A C 1 ATOM 1323 O O . LEU A 1 172 ? 62.716 87.404 -0.935 1.00 20.59 ? 172 LEU A O 1 ATOM 1324 C CB . LEU A 1 172 ? 60.711 88.296 1.377 1.00 21.03 ? 172 LEU A CB 1 ATOM 1325 C CG . LEU A 1 172 ? 59.308 88.460 1.996 1.00 24.08 ? 172 LEU A CG 1 ATOM 1326 C CD1 . LEU A 1 172 ? 59.382 88.142 3.467 1.00 24.59 ? 172 LEU A CD1 1 ATOM 1327 C CD2 . LEU A 1 172 ? 58.672 89.865 1.744 1.00 23.72 ? 172 LEU A CD2 1 ATOM 1328 N N . PRO A 1 173 ? 62.924 89.668 -0.702 1.00 21.38 ? 173 PRO A N 1 ATOM 1329 C CA . PRO A 1 173 ? 64.283 89.722 -1.228 1.00 21.05 ? 173 PRO A CA 1 ATOM 1330 C C . PRO A 1 173 ? 65.329 89.327 -0.214 1.00 21.32 ? 173 PRO A C 1 ATOM 1331 O O . PRO A 1 173 ? 66.487 89.141 -0.591 1.00 23.01 ? 173 PRO A O 1 ATOM 1332 C CB . PRO A 1 173 ? 64.438 91.207 -1.613 1.00 21.74 ? 173 PRO A CB 1 ATOM 1333 C CG . PRO A 1 173 ? 63.621 91.940 -0.632 1.00 19.80 ? 173 PRO A CG 1 ATOM 1334 C CD . PRO A 1 173 ? 62.449 91.020 -0.321 1.00 21.19 ? 173 PRO A CD 1 ATOM 1335 N N . SER A 1 174 ? 64.959 89.207 1.069 1.00 21.16 ? 174 SER A N 1 ATOM 1336 C CA . SER A 1 174 ? 65.879 88.728 2.118 1.00 20.58 ? 174 SER A CA 1 ATOM 1337 C C . SER A 1 174 ? 65.091 88.115 3.277 1.00 21.03 ? 174 SER A C 1 ATOM 1338 O O . SER A 1 174 ? 63.849 88.123 3.279 1.00 20.30 ? 174 SER A O 1 ATOM 1339 C CB . SER A 1 174 ? 66.722 89.880 2.664 1.00 20.81 ? 174 SER A CB 1 ATOM 1340 O OG . SER A 1 174 ? 65.898 90.686 3.500 1.00 20.21 ? 174 SER A OG 1 ATOM 1341 N N . THR A 1 175 ? 65.822 87.599 4.264 1.00 20.67 ? 175 THR A N 1 ATOM 1342 C CA . THR A 1 175 ? 65.209 87.105 5.498 1.00 21.15 ? 175 THR A CA 1 ATOM 1343 C C . THR A 1 175 ? 65.353 88.091 6.663 1.00 20.54 ? 175 THR A C 1 ATOM 1344 O O . THR A 1 175 ? 65.132 87.707 7.807 1.00 20.51 ? 175 THR A O 1 ATOM 1345 C CB . THR A 1 175 ? 65.814 85.765 5.940 1.00 21.66 ? 175 THR A CB 1 ATOM 1346 O OG1 . THR A 1 175 ? 67.205 85.972 6.215 1.00 23.94 ? 175 THR A OG1 1 ATOM 1347 C CG2 . THR A 1 175 ? 65.628 84.699 4.837 1.00 22.28 ? 175 THR A CG2 1 ATOM 1348 N N . ASN A 1 176 ? 65.734 89.350 6.383 1.00 19.32 ? 176 ASN A N 1 ATOM 1349 C CA . ASN A 1 176 ? 65.713 90.381 7.432 1.00 18.98 ? 176 ASN A CA 1 ATOM 1350 C C . ASN A 1 176 ? 64.323 90.991 7.528 1.00 17.97 ? 176 ASN A C 1 ATOM 1351 O O . ASN A 1 176 ? 64.093 92.021 6.951 1.00 18.48 ? 176 ASN A O 1 ATOM 1352 C CB . ASN A 1 176 ? 66.743 91.466 7.143 1.00 17.75 ? 176 ASN A CB 1 ATOM 1353 C CG . ASN A 1 176 ? 68.042 90.881 6.745 1.00 19.81 ? 176 ASN A CG 1 ATOM 1354 O OD1 . ASN A 1 176 ? 68.484 89.933 7.373 1.00 19.51 ? 176 ASN A OD1 1 ATOM 1355 N ND2 . ASN A 1 176 ? 68.656 91.402 5.689 1.00 24.49 ? 176 ASN A ND2 1 ATOM 1356 N N . VAL A 1 177 ? 63.436 90.338 8.265 1.00 17.44 ? 177 VAL A N 1 ATOM 1357 C CA . VAL A 1 177 ? 62.008 90.692 8.311 1.00 16.72 ? 177 VAL A CA 1 ATOM 1358 C C . VAL A 1 177 ? 61.651 90.944 9.783 1.00 15.74 ? 177 VAL A C 1 ATOM 1359 O O . VAL A 1 177 ? 61.942 90.089 10.622 1.00 15.23 ? 177 VAL A O 1 ATOM 1360 C CB . VAL A 1 177 ? 61.132 89.521 7.733 1.00 17.26 ? 177 VAL A CB 1 ATOM 1361 C CG1 . VAL A 1 177 ? 59.635 89.759 7.983 1.00 18.13 ? 177 VAL A CG1 1 ATOM 1362 C CG2 . VAL A 1 177 ? 61.388 89.347 6.244 1.00 17.56 ? 177 VAL A CG2 1 ATOM 1363 N N . TYR A 1 178 ? 60.971 92.064 10.073 1.00 13.80 ? 178 TYR A N 1 ATOM 1364 C CA . TYR A 1 178 ? 60.712 92.524 11.423 1.00 13.35 ? 178 TYR A CA 1 ATOM 1365 C C . TYR A 1 178 ? 59.301 93.071 11.433 1.00 14.50 ? 178 TYR A C 1 ATOM 1366 O O . TYR A 1 178 ? 58.958 93.793 10.506 1.00 14.35 ? 178 TYR A O 1 ATOM 1367 C CB . TYR A 1 178 ? 61.675 93.695 11.809 1.00 12.94 ? 178 TYR A CB 1 ATOM 1368 C CG . TYR A 1 178 ? 63.119 93.384 11.465 1.00 12.14 ? 178 TYR A CG 1 ATOM 1369 C CD1 . TYR A 1 178 ? 63.902 92.640 12.332 1.00 9.34 ? 178 TYR A CD1 1 ATOM 1370 C CD2 . TYR A 1 178 ? 63.660 93.783 10.243 1.00 12.55 ? 178 TYR A CD2 1 ATOM 1371 C CE1 . TYR A 1 178 ? 65.246 92.316 12.011 1.00 14.34 ? 178 TYR A CE1 1 ATOM 1372 C CE2 . TYR A 1 178 ? 65.025 93.463 9.895 1.00 14.30 ? 178 TYR A CE2 1 ATOM 1373 C CZ . TYR A 1 178 ? 65.785 92.720 10.788 1.00 13.68 ? 178 TYR A CZ 1 ATOM 1374 O OH . TYR A 1 178 ? 67.081 92.392 10.463 1.00 13.94 ? 178 TYR A OH 1 ATOM 1375 N N . GLY A 1 179 ? 58.525 92.765 12.478 1.00 14.36 ? 179 GLY A N 1 ATOM 1376 C CA . GLY A 1 179 ? 57.196 93.337 12.621 1.00 16.62 ? 179 GLY A CA 1 ATOM 1377 C C . GLY A 1 179 ? 56.152 92.274 12.819 1.00 16.03 ? 179 GLY A C 1 ATOM 1378 O O . GLY A 1 179 ? 56.468 91.192 13.290 1.00 17.12 ? 179 GLY A O 1 ATOM 1379 N N . LEU A 1 180 ? 54.920 92.589 12.440 1.00 16.67 ? 180 LEU A N 1 ATOM 1380 C CA . LEU A 1 180 ? 53.709 91.794 12.775 1.00 17.05 ? 180 LEU A CA 1 ATOM 1381 C C . LEU A 1 180 ? 53.383 91.845 14.250 1.00 17.27 ? 180 LEU A C 1 ATOM 1382 O O . LEU A 1 180 ? 54.272 91.982 15.084 1.00 18.35 ? 180 LEU A O 1 ATOM 1383 C CB . LEU A 1 180 ? 53.848 90.340 12.291 1.00 16.57 ? 180 LEU A CB 1 ATOM 1384 C CG . LEU A 1 180 ? 54.347 90.182 10.834 1.00 16.03 ? 180 LEU A CG 1 ATOM 1385 C CD1 . LEU A 1 180 ? 54.676 88.709 10.519 1.00 16.52 ? 180 LEU A CD1 1 ATOM 1386 C CD2 . LEU A 1 180 ? 53.307 90.806 9.844 1.00 11.89 ? 180 LEU A CD2 1 ATOM 1387 N N . GLY A 1 181 ? 52.106 91.758 14.596 1.00 17.25 ? 181 GLY A N 1 ATOM 1388 C CA . GLY A 1 181 ? 51.716 91.833 15.993 1.00 16.37 ? 181 GLY A CA 1 ATOM 1389 C C . GLY A 1 181 ? 50.212 91.650 16.152 1.00 16.90 ? 181 GLY A C 1 ATOM 1390 O O . GLY A 1 181 ? 49.482 91.705 15.173 1.00 16.47 ? 181 GLY A O 1 ATOM 1391 N N . GLU A 1 182 ? 49.747 91.506 17.385 1.00 17.05 ? 182 GLU A N 1 ATOM 1392 C CA . GLU A 1 182 ? 50.602 91.560 18.580 1.00 17.27 ? 182 GLU A CA 1 ATOM 1393 C C . GLU A 1 182 ? 50.936 90.167 19.045 1.00 17.14 ? 182 GLU A C 1 ATOM 1394 O O . GLU A 1 182 ? 50.016 89.338 19.260 1.00 17.35 ? 182 GLU A O 1 ATOM 1395 C CB . GLU A 1 182 ? 49.920 92.357 19.713 1.00 17.44 ? 182 GLU A CB 1 ATOM 1396 C CG . GLU A 1 182 ? 50.727 92.388 21.018 1.00 15.09 ? 182 GLU A CG 1 ATOM 1397 C CD . GLU A 1 182 ? 50.287 93.458 22.007 1.00 19.01 ? 182 GLU A CD 1 ATOM 1398 O OE1 . GLU A 1 182 ? 49.130 93.952 21.865 1.00 22.45 ? 182 GLU A OE1 1 ATOM 1399 O OE2 . GLU A 1 182 ? 51.080 93.790 22.957 1.00 17.36 ? 182 GLU A OE2 1 ATOM 1400 N N . HIS A 1 183 ? 52.237 89.883 19.183 1.00 16.20 ? 183 HIS A N 1 ATOM 1401 C CA . HIS A 1 183 ? 52.693 88.567 19.609 1.00 16.36 ? 183 HIS A CA 1 ATOM 1402 C C . HIS A 1 183 ? 53.950 88.667 20.508 1.00 17.39 ? 183 HIS A C 1 ATOM 1403 O O . HIS A 1 183 ? 54.624 89.711 20.545 1.00 16.90 ? 183 HIS A O 1 ATOM 1404 C CB . HIS A 1 183 ? 53.064 87.648 18.395 1.00 16.70 ? 183 HIS A CB 1 ATOM 1405 C CG . HIS A 1 183 ? 52.171 87.771 17.188 1.00 16.01 ? 183 HIS A CG 1 ATOM 1406 N ND1 . HIS A 1 183 ? 50.887 87.250 17.142 1.00 18.72 ? 183 HIS A ND1 1 ATOM 1407 C CD2 . HIS A 1 183 ? 52.404 88.288 15.957 1.00 14.26 ? 183 HIS A CD2 1 ATOM 1408 C CE1 . HIS A 1 183 ? 50.350 87.492 15.956 1.00 10.94 ? 183 HIS A CE1 1 ATOM 1409 N NE2 . HIS A 1 183 ? 51.248 88.122 15.217 1.00 15.94 ? 183 HIS A NE2 1 ATOM 1410 N N . VAL A 1 184 ? 54.288 87.556 21.169 1.00 17.73 ? 184 VAL A N 1 ATOM 1411 C CA . VAL A 1 184 ? 55.651 87.314 21.687 1.00 18.32 ? 184 VAL A CA 1 ATOM 1412 C C . VAL A 1 184 ? 56.399 86.449 20.657 1.00 19.10 ? 184 VAL A C 1 ATOM 1413 O O . VAL A 1 184 ? 56.175 85.227 20.546 1.00 19.38 ? 184 VAL A O 1 ATOM 1414 C CB . VAL A 1 184 ? 55.633 86.672 23.088 1.00 18.28 ? 184 VAL A CB 1 ATOM 1415 C CG1 . VAL A 1 184 ? 57.049 86.272 23.533 1.00 20.56 ? 184 VAL A CG1 1 ATOM 1416 C CG2 . VAL A 1 184 ? 54.997 87.642 24.102 1.00 17.43 ? 184 VAL A CG2 1 ATOM 1417 N N . HIS A 1 185 ? 57.238 87.105 19.852 1.00 18.78 ? 185 HIS A N 1 ATOM 1418 C CA . HIS A 1 185 ? 57.957 86.433 18.782 1.00 19.11 ? 185 HIS A CA 1 ATOM 1419 C C . HIS A 1 185 ? 59.216 85.819 19.367 1.00 19.44 ? 185 HIS A C 1 ATOM 1420 O O . HIS A 1 185 ? 59.779 84.918 18.786 1.00 19.17 ? 185 HIS A O 1 ATOM 1421 C CB . HIS A 1 185 ? 58.330 87.412 17.651 1.00 18.69 ? 185 HIS A CB 1 ATOM 1422 C CG . HIS A 1 185 ? 57.152 87.980 16.922 1.00 17.05 ? 185 HIS A CG 1 ATOM 1423 N ND1 . HIS A 1 185 ? 57.068 89.309 16.567 1.00 13.05 ? 185 HIS A ND1 1 ATOM 1424 C CD2 . HIS A 1 185 ? 56.006 87.402 16.481 1.00 18.36 ? 185 HIS A CD2 1 ATOM 1425 C CE1 . HIS A 1 185 ? 55.928 89.525 15.930 1.00 18.08 ? 185 HIS A CE1 1 ATOM 1426 N NE2 . HIS A 1 185 ? 55.266 88.383 15.862 1.00 15.34 ? 185 HIS A NE2 1 ATOM 1427 N N . GLN A 1 186 ? 59.666 86.341 20.505 1.00 20.14 ? 186 GLN A N 1 ATOM 1428 C CA . GLN A 1 186 ? 60.866 85.838 21.200 1.00 21.90 ? 186 GLN A CA 1 ATOM 1429 C C . GLN A 1 186 ? 62.178 86.332 20.596 1.00 23.38 ? 186 GLN A C 1 ATOM 1430 O O . GLN A 1 186 ? 63.080 86.734 21.322 1.00 24.19 ? 186 GLN A O 1 ATOM 1431 C CB . GLN A 1 186 ? 60.881 84.302 21.346 1.00 21.59 ? 186 GLN A CB 1 ATOM 1432 C CG . GLN A 1 186 ? 59.621 83.748 21.998 1.00 21.07 ? 186 GLN A CG 1 ATOM 1433 C CD . GLN A 1 186 ? 59.681 82.282 22.370 1.00 22.90 ? 186 GLN A CD 1 ATOM 1434 O OE1 . GLN A 1 186 ? 60.718 81.767 22.763 1.00 22.60 ? 186 GLN A OE1 1 ATOM 1435 N NE2 . GLN A 1 186 ? 58.533 81.609 22.292 1.00 24.91 ? 186 GLN A NE2 1 ATOM 1436 N N . GLN A 1 187 ? 62.281 86.270 19.274 1.00 24.13 ? 187 GLN A N 1 ATOM 1437 C CA . GLN A 1 187 ? 63.415 86.814 18.518 1.00 23.92 ? 187 GLN A CA 1 ATOM 1438 C C . GLN A 1 187 ? 62.871 88.073 17.831 1.00 22.85 ? 187 GLN A C 1 ATOM 1439 O O . GLN A 1 187 ? 61.669 88.202 17.679 1.00 23.00 ? 187 GLN A O 1 ATOM 1440 C CB . GLN A 1 187 ? 63.864 85.773 17.486 1.00 24.22 ? 187 GLN A CB 1 ATOM 1441 C CG . GLN A 1 187 ? 64.733 84.616 18.071 1.00 29.77 ? 187 GLN A CG 1 ATOM 1442 C CD . GLN A 1 187 ? 63.946 83.565 18.907 1.00 35.95 ? 187 GLN A CD 1 ATOM 1443 O OE1 . GLN A 1 187 ? 62.949 82.956 18.441 1.00 36.94 ? 187 GLN A OE1 1 ATOM 1444 N NE2 . GLN A 1 187 ? 64.422 83.327 20.137 1.00 37.75 ? 187 GLN A NE2 1 ATOM 1445 N N . TYR A 1 188 ? 63.730 89.019 17.460 1.00 20.80 ? 188 TYR A N 1 ATOM 1446 C CA . TYR A 1 188 ? 63.285 90.190 16.742 1.00 19.45 ? 188 TYR A CA 1 ATOM 1447 C C . TYR A 1 188 ? 63.250 89.925 15.233 1.00 20.37 ? 188 TYR A C 1 ATOM 1448 O O . TYR A 1 188 ? 62.243 90.191 14.559 1.00 19.48 ? 188 TYR A O 1 ATOM 1449 C CB . TYR A 1 188 ? 64.135 91.420 17.114 1.00 19.00 ? 188 TYR A CB 1 ATOM 1450 C CG . TYR A 1 188 ? 63.690 92.684 16.444 1.00 17.21 ? 188 TYR A CG 1 ATOM 1451 C CD1 . TYR A 1 188 ? 62.370 93.157 16.599 1.00 15.64 ? 188 TYR A CD1 1 ATOM 1452 C CD2 . TYR A 1 188 ? 64.575 93.421 15.681 1.00 15.39 ? 188 TYR A CD2 1 ATOM 1453 C CE1 . TYR A 1 188 ? 61.951 94.296 15.997 1.00 15.68 ? 188 TYR A CE1 1 ATOM 1454 C CE2 . TYR A 1 188 ? 64.155 94.599 15.063 1.00 14.11 ? 188 TYR A CE2 1 ATOM 1455 C CZ . TYR A 1 188 ? 62.861 95.032 15.233 1.00 15.81 ? 188 TYR A CZ 1 ATOM 1456 O OH . TYR A 1 188 ? 62.436 96.180 14.605 1.00 16.09 ? 188 TYR A OH 1 ATOM 1457 N N . ARG A 1 189 ? 64.337 89.382 14.690 1.00 20.56 ? 189 ARG A N 1 ATOM 1458 C CA . ARG A 1 189 ? 64.300 88.982 13.282 1.00 21.93 ? 189 ARG A CA 1 ATOM 1459 C C . ARG A 1 189 ? 63.497 87.670 13.149 1.00 22.93 ? 189 ARG A C 1 ATOM 1460 O O . ARG A 1 189 ? 63.780 86.696 13.851 1.00 21.31 ? 189 ARG A O 1 ATOM 1461 C CB . ARG A 1 189 ? 65.712 88.780 12.726 1.00 20.48 ? 189 ARG A CB 1 ATOM 1462 C CG . ARG A 1 189 ? 65.732 88.815 11.215 1.00 21.14 ? 189 ARG A CG 1 ATOM 1463 C CD . ARG A 1 189 ? 67.109 88.551 10.700 1.00 21.67 ? 189 ARG A CD 1 ATOM 1464 N NE . ARG A 1 189 ? 67.342 87.145 10.867 1.00 27.70 ? 189 ARG A NE 1 ATOM 1465 C CZ . ARG A 1 189 ? 68.493 86.530 10.740 1.00 35.18 ? 189 ARG A CZ 1 ATOM 1466 N NH1 . ARG A 1 189 ? 69.627 87.218 10.457 1.00 38.53 ? 189 ARG A NH1 1 ATOM 1467 N NH2 . ARG A 1 189 ? 68.486 85.210 10.911 1.00 35.42 ? 189 ARG A NH2 1 ATOM 1468 N N . HIS A 1 190 ? 62.493 87.664 12.275 1.00 24.68 ? 190 HIS A N 1 ATOM 1469 C CA . HIS A 1 190 ? 61.783 86.412 11.915 1.00 28.31 ? 190 HIS A CA 1 ATOM 1470 C C . HIS A 1 190 ? 62.712 85.487 11.105 1.00 29.49 ? 190 HIS A C 1 ATOM 1471 O O . HIS A 1 190 ? 63.126 85.863 10.019 1.00 31.81 ? 190 HIS A O 1 ATOM 1472 C CB . HIS A 1 190 ? 60.553 86.731 11.061 1.00 25.72 ? 190 HIS A CB 1 ATOM 1473 C CG . HIS A 1 190 ? 59.464 87.420 11.806 1.00 24.89 ? 190 HIS A CG 1 ATOM 1474 N ND1 . HIS A 1 190 ? 59.423 88.790 11.978 1.00 23.26 ? 190 HIS A ND1 1 ATOM 1475 C CD2 . HIS A 1 190 ? 58.376 86.931 12.441 1.00 25.28 ? 190 HIS A CD2 1 ATOM 1476 C CE1 . HIS A 1 190 ? 58.353 89.112 12.686 1.00 21.82 ? 190 HIS A CE1 1 ATOM 1477 N NE2 . HIS A 1 190 ? 57.696 88.005 12.970 1.00 24.02 ? 190 HIS A NE2 1 ATOM 1478 N N . ASP A 1 191 ? 63.039 84.314 11.639 1.00 32.02 ? 191 ASP A N 1 ATOM 1479 C CA . ASP A 1 191 ? 63.904 83.269 10.989 1.00 33.37 ? 191 ASP A CA 1 ATOM 1480 C C . ASP A 1 191 ? 63.537 82.940 9.509 1.00 34.45 ? 191 ASP A C 1 ATOM 1481 O O . ASP A 1 191 ? 64.423 82.593 8.693 1.00 34.03 ? 191 ASP A O 1 ATOM 1482 C CB . ASP A 1 191 ? 63.795 81.946 11.809 1.00 34.93 ? 191 ASP A CB 1 ATOM 1483 C CG . ASP A 1 191 ? 62.312 81.616 12.197 1.00 39.86 ? 191 ASP A CG 1 ATOM 1484 O OD1 . ASP A 1 191 ? 61.461 82.532 12.026 1.00 42.68 ? 191 ASP A OD1 1 ATOM 1485 O OD2 . ASP A 1 191 ? 61.984 80.481 12.675 1.00 43.66 ? 191 ASP A OD2 1 ATOM 1486 N N . MET A 1 192 ? 62.218 83.011 9.221 1.00 33.91 ? 192 MET A N 1 ATOM 1487 C CA . MET A 1 192 ? 61.575 82.669 7.930 1.00 32.16 ? 192 MET A CA 1 ATOM 1488 C C . MET A 1 192 ? 61.322 81.175 7.744 1.00 31.57 ? 192 MET A C 1 ATOM 1489 O O . MET A 1 192 ? 60.908 80.728 6.684 1.00 31.30 ? 192 MET A O 1 ATOM 1490 C CB . MET A 1 192 ? 62.286 83.292 6.719 1.00 32.62 ? 192 MET A CB 1 ATOM 1491 C CG . MET A 1 192 ? 62.198 84.813 6.663 1.00 30.20 ? 192 MET A CG 1 ATOM 1492 S SD . MET A 1 192 ? 60.569 85.391 7.089 1.00 29.14 ? 192 MET A SD 1 ATOM 1493 C CE . MET A 1 192 ? 59.705 85.122 5.539 1.00 26.08 ? 192 MET A CE 1 ATOM 1494 N N A ASN A 1 193 ? 61.575 80.398 8.787 0.50 30.89 ? 193 ASN A N 1 ATOM 1495 N N B ASN A 1 193 ? 61.574 80.396 8.785 0.50 30.88 ? 193 ASN A N 1 ATOM 1496 C CA A ASN A 1 193 ? 61.132 79.019 8.794 0.50 30.07 ? 193 ASN A CA 1 ATOM 1497 C CA B ASN A 1 193 ? 61.174 79.006 8.778 0.50 30.07 ? 193 ASN A CA 1 ATOM 1498 C C A ASN A 1 193 ? 59.635 78.988 9.011 0.50 29.46 ? 193 ASN A C 1 ATOM 1499 C C B ASN A 1 193 ? 59.696 78.980 8.382 0.50 29.57 ? 193 ASN A C 1 ATOM 1500 O O A ASN A 1 193 ? 59.058 79.972 9.507 0.50 29.37 ? 193 ASN A O 1 ATOM 1501 O O B ASN A 1 193 ? 59.178 79.964 7.846 0.50 30.16 ? 193 ASN A O 1 ATOM 1502 C CB A ASN A 1 193 ? 61.883 78.197 9.833 0.50 30.35 ? 193 ASN A CB 1 ATOM 1503 C CB B ASN A 1 193 ? 61.408 78.395 10.163 0.50 30.21 ? 193 ASN A CB 1 ATOM 1504 C CG A ASN A 1 193 ? 63.225 77.732 9.326 0.50 31.61 ? 193 ASN A CG 1 ATOM 1505 C CG B ASN A 1 193 ? 61.816 76.927 10.113 0.50 30.86 ? 193 ASN A CG 1 ATOM 1506 O OD1 A ASN A 1 193 ? 64.254 78.030 9.924 0.50 33.81 ? 193 ASN A OD1 1 ATOM 1507 O OD1 B ASN A 1 193 ? 61.996 76.301 11.158 0.50 31.63 ? 193 ASN A OD1 1 ATOM 1508 N ND2 A ASN A 1 193 ? 63.228 77.019 8.197 0.50 32.61 ? 193 ASN A ND2 1 ATOM 1509 N ND2 B ASN A 1 193 ? 61.965 76.372 8.907 0.50 30.14 ? 193 ASN A ND2 1 ATOM 1510 N N . TRP A 1 194 ? 59.026 77.866 8.624 1.00 28.18 ? 194 TRP A N 1 ATOM 1511 C CA . TRP A 1 194 ? 57.591 77.742 8.417 1.00 26.34 ? 194 TRP A CA 1 ATOM 1512 C C . TRP A 1 194 ? 56.857 78.118 9.694 1.00 26.26 ? 194 TRP A C 1 ATOM 1513 O O . TRP A 1 194 ? 56.901 77.355 10.657 1.00 26.65 ? 194 TRP A O 1 ATOM 1514 C CB . TRP A 1 194 ? 57.323 76.264 8.131 1.00 24.58 ? 194 TRP A CB 1 ATOM 1515 C CG . TRP A 1 194 ? 58.060 75.749 6.917 1.00 23.41 ? 194 TRP A CG 1 ATOM 1516 C CD1 . TRP A 1 194 ? 59.335 75.191 6.866 1.00 22.43 ? 194 TRP A CD1 1 ATOM 1517 C CD2 . TRP A 1 194 ? 57.582 75.778 5.583 1.00 21.74 ? 194 TRP A CD2 1 ATOM 1518 N NE1 . TRP A 1 194 ? 59.649 74.879 5.568 1.00 21.21 ? 194 TRP A NE1 1 ATOM 1519 C CE2 . TRP A 1 194 ? 58.590 75.220 4.761 1.00 22.00 ? 194 TRP A CE2 1 ATOM 1520 C CE3 . TRP A 1 194 ? 56.385 76.222 4.991 1.00 22.64 ? 194 TRP A CE3 1 ATOM 1521 C CZ2 . TRP A 1 194 ? 58.436 75.086 3.383 1.00 21.16 ? 194 TRP A CZ2 1 ATOM 1522 C CZ3 . TRP A 1 194 ? 56.242 76.104 3.600 1.00 21.72 ? 194 TRP A CZ3 1 ATOM 1523 C CH2 . TRP A 1 194 ? 57.268 75.541 2.820 1.00 22.17 ? 194 TRP A CH2 1 ATOM 1524 N N . LYS A 1 195 ? 56.178 79.265 9.711 1.00 25.30 ? 195 LYS A N 1 ATOM 1525 C CA . LYS A 1 195 ? 55.670 79.851 10.954 1.00 24.56 ? 195 LYS A CA 1 ATOM 1526 C C . LYS A 1 195 ? 54.373 80.563 10.580 1.00 23.63 ? 195 LYS A C 1 ATOM 1527 O O . LYS A 1 195 ? 54.316 81.223 9.541 1.00 23.55 ? 195 LYS A O 1 ATOM 1528 C CB . LYS A 1 195 ? 56.752 80.807 11.488 1.00 25.33 ? 195 LYS A CB 1 ATOM 1529 C CG . LYS A 1 195 ? 56.886 81.019 12.984 1.00 30.03 ? 195 LYS A CG 1 ATOM 1530 C CD . LYS A 1 195 ? 56.359 79.890 13.920 1.00 35.16 ? 195 LYS A CD 1 ATOM 1531 C CE . LYS A 1 195 ? 56.073 80.435 15.353 1.00 34.08 ? 195 LYS A CE 1 ATOM 1532 N NZ . LYS A 1 195 ? 54.711 80.065 15.995 1.00 35.97 ? 195 LYS A NZ 1 ATOM 1533 N N . THR A 1 196 ? 53.319 80.354 11.363 1.00 21.46 ? 196 THR A N 1 ATOM 1534 C CA . THR A 1 196 ? 52.037 80.995 11.153 1.00 21.10 ? 196 THR A CA 1 ATOM 1535 C C . THR A 1 196 ? 51.709 81.854 12.390 1.00 19.77 ? 196 THR A C 1 ATOM 1536 O O . THR A 1 196 ? 51.729 81.342 13.509 1.00 20.16 ? 196 THR A O 1 ATOM 1537 C CB . THR A 1 196 ? 50.911 79.931 10.930 1.00 21.31 ? 196 THR A CB 1 ATOM 1538 O OG1 . THR A 1 196 ? 51.147 79.213 9.697 1.00 23.49 ? 196 THR A OG1 1 ATOM 1539 C CG2 . THR A 1 196 ? 49.586 80.584 10.824 1.00 22.61 ? 196 THR A CG2 1 ATOM 1540 N N . TRP A 1 197 ? 51.421 83.146 12.186 1.00 17.94 ? 197 TRP A N 1 ATOM 1541 C CA . TRP A 1 197 ? 51.096 84.079 13.268 1.00 16.90 ? 197 TRP A CA 1 ATOM 1542 C C . TRP A 1 197 ? 49.648 84.537 13.143 1.00 16.46 ? 197 TRP A C 1 ATOM 1543 O O . TRP A 1 197 ? 49.351 85.317 12.238 1.00 17.28 ? 197 TRP A O 1 ATOM 1544 C CB . TRP A 1 197 ? 52.027 85.308 13.229 1.00 16.13 ? 197 TRP A CB 1 ATOM 1545 C CG . TRP A 1 197 ? 53.444 84.921 13.552 1.00 17.75 ? 197 TRP A CG 1 ATOM 1546 C CD1 . TRP A 1 197 ? 54.485 84.746 12.661 1.00 18.40 ? 197 TRP A CD1 1 ATOM 1547 C CD2 . TRP A 1 197 ? 53.974 84.594 14.852 1.00 17.97 ? 197 TRP A CD2 1 ATOM 1548 N NE1 . TRP A 1 197 ? 55.632 84.359 13.341 1.00 18.25 ? 197 TRP A NE1 1 ATOM 1549 C CE2 . TRP A 1 197 ? 55.339 84.253 14.679 1.00 16.95 ? 197 TRP A CE2 1 ATOM 1550 C CE3 . TRP A 1 197 ? 53.432 84.583 16.155 1.00 18.99 ? 197 TRP A CE3 1 ATOM 1551 C CZ2 . TRP A 1 197 ? 56.160 83.893 15.762 1.00 20.04 ? 197 TRP A CZ2 1 ATOM 1552 C CZ3 . TRP A 1 197 ? 54.259 84.235 17.227 1.00 17.35 ? 197 TRP A CZ3 1 ATOM 1553 C CH2 . TRP A 1 197 ? 55.598 83.884 17.018 1.00 17.71 ? 197 TRP A CH2 1 ATOM 1554 N N . PRO A 1 198 ? 48.758 84.088 14.052 1.00 16.20 ? 198 PRO A N 1 ATOM 1555 C CA . PRO A 1 198 ? 47.370 84.544 14.006 1.00 15.62 ? 198 PRO A CA 1 ATOM 1556 C C . PRO A 1 198 ? 47.271 85.946 14.560 1.00 16.73 ? 198 PRO A C 1 ATOM 1557 O O . PRO A 1 198 ? 48.042 86.319 15.498 1.00 16.66 ? 198 PRO A O 1 ATOM 1558 C CB . PRO A 1 198 ? 46.629 83.563 14.943 1.00 15.82 ? 198 PRO A CB 1 ATOM 1559 C CG . PRO A 1 198 ? 47.678 83.065 15.895 1.00 16.89 ? 198 PRO A CG 1 ATOM 1560 C CD . PRO A 1 198 ? 48.997 83.101 15.134 1.00 15.99 ? 198 PRO A CD 1 ATOM 1561 N N . ILE A 1 199 ? 46.345 86.723 13.991 1.00 15.92 ? 199 ILE A N 1 ATOM 1562 C CA . ILE A 1 199 ? 46.116 88.077 14.435 1.00 16.29 ? 199 ILE A CA 1 ATOM 1563 C C . ILE A 1 199 ? 44.641 88.302 14.684 1.00 17.61 ? 199 ILE A C 1 ATOM 1564 O O . ILE A 1 199 ? 43.845 88.319 13.749 1.00 16.55 ? 199 ILE A O 1 ATOM 1565 C CB . ILE A 1 199 ? 46.616 89.135 13.397 1.00 17.16 ? 199 ILE A CB 1 ATOM 1566 C CG1 . ILE A 1 199 ? 48.152 89.015 13.199 1.00 14.54 ? 199 ILE A CG1 1 ATOM 1567 C CG2 . ILE A 1 199 ? 46.334 90.513 13.915 1.00 16.21 ? 199 ILE A CG2 1 ATOM 1568 C CD1 . ILE A 1 199 ? 48.722 90.018 12.136 1.00 15.64 ? 199 ILE A CD1 1 ATOM 1569 N N . PHE A 1 200 ? 44.288 88.487 15.954 1.00 17.23 ? 200 PHE A N 1 ATOM 1570 C CA . PHE A 1 200 ? 42.926 88.711 16.316 1.00 18.55 ? 200 PHE A CA 1 ATOM 1571 C C . PHE A 1 200 ? 42.974 89.101 17.781 1.00 18.50 ? 200 PHE A C 1 ATOM 1572 O O . PHE A 1 200 ? 43.392 88.305 18.641 1.00 19.36 ? 200 PHE A O 1 ATOM 1573 C CB . PHE A 1 200 ? 42.113 87.415 16.089 1.00 18.48 ? 200 PHE A CB 1 ATOM 1574 C CG . PHE A 1 200 ? 40.650 87.570 16.286 1.00 20.94 ? 200 PHE A CG 1 ATOM 1575 C CD1 . PHE A 1 200 ? 39.872 88.325 15.389 1.00 21.64 ? 200 PHE A CD1 1 ATOM 1576 C CD2 . PHE A 1 200 ? 40.020 86.926 17.351 1.00 22.54 ? 200 PHE A CD2 1 ATOM 1577 C CE1 . PHE A 1 200 ? 38.510 88.437 15.563 1.00 20.47 ? 200 PHE A CE1 1 ATOM 1578 C CE2 . PHE A 1 200 ? 38.660 87.051 17.541 1.00 18.85 ? 200 PHE A CE2 1 ATOM 1579 C CZ . PHE A 1 200 ? 37.895 87.801 16.640 1.00 19.13 ? 200 PHE A CZ 1 ATOM 1580 N N . ASN A 1 201 ? 42.572 90.339 18.048 1.00 17.92 ? 201 ASN A N 1 ATOM 1581 C CA . ASN A 1 201 ? 42.635 90.924 19.397 1.00 17.70 ? 201 ASN A CA 1 ATOM 1582 C C . ASN A 1 201 ? 41.993 90.043 20.466 1.00 18.29 ? 201 ASN A C 1 ATOM 1583 O O . ASN A 1 201 ? 40.803 89.676 20.385 1.00 17.91 ? 201 ASN A O 1 ATOM 1584 C CB . ASN A 1 201 ? 42.024 92.308 19.359 1.00 17.32 ? 201 ASN A CB 1 ATOM 1585 C CG . ASN A 1 201 ? 42.803 93.236 18.433 1.00 15.77 ? 201 ASN A CG 1 ATOM 1586 O OD1 . ASN A 1 201 ? 43.781 92.805 17.827 1.00 17.68 ? 201 ASN A OD1 1 ATOM 1587 N ND2 . ASN A 1 201 ? 42.390 94.475 18.323 1.00 11.71 ? 201 ASN A ND2 1 ATOM 1588 N N . ARG A 1 202 ? 42.806 89.667 21.445 1.00 17.97 ? 202 ARG A N 1 ATOM 1589 C CA . ARG A 1 202 ? 42.397 88.695 22.413 1.00 18.93 ? 202 ARG A CA 1 ATOM 1590 C C . ARG A 1 202 ? 43.110 88.892 23.765 1.00 20.25 ? 202 ARG A C 1 ATOM 1591 O O . ARG A 1 202 ? 44.331 89.118 23.835 1.00 19.42 ? 202 ARG A O 1 ATOM 1592 C CB . ARG A 1 202 ? 42.593 87.282 21.834 1.00 18.74 ? 202 ARG A CB 1 ATOM 1593 C CG . ARG A 1 202 ? 42.586 86.182 22.877 1.00 19.83 ? 202 ARG A CG 1 ATOM 1594 C CD . ARG A 1 202 ? 41.165 85.859 23.364 1.00 21.57 ? 202 ARG A CD 1 ATOM 1595 N NE . ARG A 1 202 ? 41.203 84.958 24.513 1.00 22.16 ? 202 ARG A NE 1 ATOM 1596 C CZ . ARG A 1 202 ? 41.023 83.647 24.442 1.00 24.85 ? 202 ARG A CZ 1 ATOM 1597 N NH1 . ARG A 1 202 ? 40.758 83.069 23.276 1.00 23.66 ? 202 ARG A NH1 1 ATOM 1598 N NH2 . ARG A 1 202 ? 41.098 82.913 25.547 1.00 25.51 ? 202 ARG A NH2 1 ATOM 1599 N N . ASP A 1 203 ? 42.330 88.835 24.841 1.00 20.70 ? 203 ASP A N 1 ATOM 1600 C CA . ASP A 1 203 ? 42.888 88.797 26.180 1.00 21.74 ? 203 ASP A CA 1 ATOM 1601 C C . ASP A 1 203 ? 43.521 87.438 26.451 1.00 22.89 ? 203 ASP A C 1 ATOM 1602 O O . ASP A 1 203 ? 42.825 86.480 26.782 1.00 23.01 ? 203 ASP A O 1 ATOM 1603 C CB . ASP A 1 203 ? 41.774 89.074 27.191 1.00 21.00 ? 203 ASP A CB 1 ATOM 1604 C CG . ASP A 1 203 ? 42.257 89.056 28.622 1.00 23.00 ? 203 ASP A CG 1 ATOM 1605 O OD1 . ASP A 1 203 ? 43.459 88.724 28.875 1.00 20.31 ? 203 ASP A OD1 1 ATOM 1606 O OD2 . ASP A 1 203 ? 41.405 89.380 29.507 1.00 24.31 ? 203 ASP A OD2 1 ATOM 1607 N N . THR A 1 204 ? 44.835 87.340 26.281 1.00 24.18 ? 204 THR A N 1 ATOM 1608 C CA . THR A 1 204 ? 45.546 86.124 26.618 1.00 25.88 ? 204 THR A CA 1 ATOM 1609 C C . THR A 1 204 ? 46.941 86.479 27.057 1.00 24.94 ? 204 THR A C 1 ATOM 1610 O O . THR A 1 204 ? 47.453 87.517 26.670 1.00 25.24 ? 204 THR A O 1 ATOM 1611 C CB . THR A 1 204 ? 45.734 85.228 25.435 1.00 26.55 ? 204 THR A CB 1 ATOM 1612 O OG1 . THR A 1 204 ? 46.384 85.960 24.398 1.00 31.66 ? 204 THR A OG1 1 ATOM 1613 C CG2 . THR A 1 204 ? 44.411 84.734 24.904 1.00 31.74 ? 204 THR A CG2 1 ATOM 1614 N N . THR A 1 205 ? 47.557 85.584 27.822 1.00 23.72 ? 205 THR A N 1 ATOM 1615 C CA . THR A 1 205 ? 48.897 85.760 28.365 1.00 23.70 ? 205 THR A CA 1 ATOM 1616 C C . THR A 1 205 ? 49.945 85.848 27.267 1.00 23.80 ? 205 THR A C 1 ATOM 1617 O O . THR A 1 205 ? 50.019 84.957 26.409 1.00 24.00 ? 205 THR A O 1 ATOM 1618 C CB . THR A 1 205 ? 49.249 84.556 29.244 1.00 23.97 ? 205 THR A CB 1 ATOM 1619 O OG1 . THR A 1 205 ? 48.167 84.299 30.135 1.00 24.22 ? 205 THR A OG1 1 ATOM 1620 C CG2 . THR A 1 205 ? 50.542 84.777 30.035 1.00 22.91 ? 205 THR A CG2 1 ATOM 1621 N N . PRO A 1 206 ? 50.789 86.894 27.314 1.00 23.77 ? 206 PRO A N 1 ATOM 1622 C CA . PRO A 1 206 ? 51.947 86.931 26.438 1.00 24.18 ? 206 PRO A CA 1 ATOM 1623 C C . PRO A 1 206 ? 53.006 85.939 26.922 1.00 24.49 ? 206 PRO A C 1 ATOM 1624 O O . PRO A 1 206 ? 53.861 86.261 27.758 1.00 25.08 ? 206 PRO A O 1 ATOM 1625 C CB . PRO A 1 206 ? 52.428 88.388 26.534 1.00 24.11 ? 206 PRO A CB 1 ATOM 1626 C CG . PRO A 1 206 ? 51.927 88.890 27.825 1.00 24.69 ? 206 PRO A CG 1 ATOM 1627 C CD . PRO A 1 206 ? 50.689 88.090 28.173 1.00 23.84 ? 206 PRO A CD 1 ATOM 1628 N N . ASN A 1 207 ? 52.930 84.729 26.396 1.00 24.49 ? 207 ASN A N 1 ATOM 1629 C CA . ASN A 1 207 ? 53.799 83.648 26.846 1.00 24.10 ? 207 ASN A CA 1 ATOM 1630 C C . ASN A 1 207 ? 54.535 83.072 25.672 1.00 24.03 ? 207 ASN A C 1 ATOM 1631 O O . ASN A 1 207 ? 54.560 83.684 24.602 1.00 23.68 ? 207 ASN A O 1 ATOM 1632 C CB . ASN A 1 207 ? 52.985 82.573 27.572 1.00 23.47 ? 207 ASN A CB 1 ATOM 1633 C CG . ASN A 1 207 ? 51.865 81.989 26.706 1.00 24.61 ? 207 ASN A CG 1 ATOM 1634 O OD1 . ASN A 1 207 ? 51.887 82.093 25.489 1.00 23.29 ? 207 ASN A OD1 1 ATOM 1635 N ND2 . ASN A 1 207 ? 50.901 81.340 27.344 1.00 22.68 ? 207 ASN A ND2 1 ATOM 1636 N N . GLY A 1 208 ? 55.126 81.894 25.874 1.00 24.21 ? 208 GLY A N 1 ATOM 1637 C CA . GLY A 1 208 ? 55.952 81.232 24.875 1.00 24.53 ? 208 GLY A CA 1 ATOM 1638 C C . GLY A 1 208 ? 55.219 80.458 23.798 1.00 24.60 ? 208 GLY A C 1 ATOM 1639 O O . GLY A 1 208 ? 55.864 79.843 22.971 1.00 24.73 ? 208 GLY A O 1 ATOM 1640 N N . ASN A 1 209 ? 53.884 80.504 23.788 1.00 24.99 ? 209 ASN A N 1 ATOM 1641 C CA . ASN A 1 209 ? 53.085 79.719 22.848 1.00 25.98 ? 209 ASN A CA 1 ATOM 1642 C C . ASN A 1 209 ? 52.776 80.367 21.509 1.00 24.99 ? 209 ASN A C 1 ATOM 1643 O O . ASN A 1 209 ? 52.077 79.760 20.682 1.00 25.60 ? 209 ASN A O 1 ATOM 1644 C CB . ASN A 1 209 ? 51.754 79.312 23.501 1.00 27.64 ? 209 ASN A CB 1 ATOM 1645 C CG . ASN A 1 209 ? 51.923 78.277 24.584 1.00 34.40 ? 209 ASN A CG 1 ATOM 1646 O OD1 . ASN A 1 209 ? 52.751 77.366 24.463 1.00 40.79 ? 209 ASN A OD1 1 ATOM 1647 N ND2 . ASN A 1 209 ? 51.116 78.400 25.654 1.00 43.99 ? 209 ASN A ND2 1 ATOM 1648 N N . GLY A 1 210 ? 53.191 81.617 21.322 1.00 23.42 ? 210 GLY A N 1 ATOM 1649 C CA . GLY A 1 210 ? 53.038 82.281 20.028 1.00 22.70 ? 210 GLY A CA 1 ATOM 1650 C C . GLY A 1 210 ? 51.608 82.552 19.565 1.00 21.82 ? 210 GLY A C 1 ATOM 1651 O O . GLY A 1 210 ? 51.325 82.499 18.355 1.00 21.70 ? 210 GLY A O 1 ATOM 1652 N N . THR A 1 211 ? 50.698 82.820 20.503 1.00 20.56 ? 211 THR A N 1 ATOM 1653 C CA . THR A 1 211 ? 49.286 83.025 20.122 1.00 19.38 ? 211 THR A CA 1 ATOM 1654 C C . THR A 1 211 ? 49.028 84.484 19.695 1.00 18.39 ? 211 THR A C 1 ATOM 1655 O O . THR A 1 211 ? 49.897 85.368 19.899 1.00 17.14 ? 211 THR A O 1 ATOM 1656 C CB . THR A 1 211 ? 48.318 82.711 21.289 1.00 20.00 ? 211 THR A CB 1 ATOM 1657 O OG1 . THR A 1 211 ? 48.368 83.762 22.280 1.00 21.98 ? 211 THR A OG1 1 ATOM 1658 C CG2 . THR A 1 211 ? 48.640 81.383 21.935 1.00 19.38 ? 211 THR A CG2 1 ATOM 1659 N N . ASN A 1 212 ? 47.843 84.738 19.117 1.00 16.29 ? 212 ASN A N 1 ATOM 1660 C CA . ASN A 1 212 ? 47.314 86.078 19.018 1.00 16.28 ? 212 ASN A CA 1 ATOM 1661 C C . ASN A 1 212 ? 47.210 86.759 20.394 1.00 16.68 ? 212 ASN A C 1 ATOM 1662 O O . ASN A 1 212 ? 46.714 86.156 21.397 1.00 17.83 ? 212 ASN A O 1 ATOM 1663 C CB . ASN A 1 212 ? 45.925 86.090 18.316 1.00 15.57 ? 212 ASN A CB 1 ATOM 1664 C CG . ASN A 1 212 ? 44.963 85.079 18.917 1.00 17.43 ? 212 ASN A CG 1 ATOM 1665 O OD1 . ASN A 1 212 ? 45.335 83.943 19.143 1.00 15.08 ? 212 ASN A OD1 1 ATOM 1666 N ND2 . ASN A 1 212 ? 43.720 85.504 19.199 1.00 14.85 ? 212 ASN A ND2 1 ATOM 1667 N N . LEU A 1 213 ? 47.648 88.017 20.470 1.00 15.59 ? 213 LEU A N 1 ATOM 1668 C CA . LEU A 1 213 ? 47.499 88.764 21.734 1.00 15.45 ? 213 LEU A CA 1 ATOM 1669 C C . LEU A 1 213 ? 46.559 89.941 21.574 1.00 15.24 ? 213 LEU A C 1 ATOM 1670 O O . LEU A 1 213 ? 45.662 89.851 20.755 1.00 15.08 ? 213 LEU A O 1 ATOM 1671 C CB . LEU A 1 213 ? 48.859 89.150 22.369 1.00 15.55 ? 213 LEU A CB 1 ATOM 1672 C CG . LEU A 1 213 ? 49.772 87.938 22.589 1.00 15.75 ? 213 LEU A CG 1 ATOM 1673 C CD1 . LEU A 1 213 ? 51.152 88.461 22.940 1.00 15.68 ? 213 LEU A CD1 1 ATOM 1674 C CD2 . LEU A 1 213 ? 49.237 87.045 23.716 1.00 17.27 ? 213 LEU A CD2 1 ATOM 1675 N N . TYR A 1 214 ? 46.804 91.033 22.309 1.00 14.97 ? 214 TYR A N 1 ATOM 1676 C CA . TYR A 1 214 ? 45.833 92.117 22.507 1.00 16.54 ? 214 TYR A CA 1 ATOM 1677 C C . TYR A 1 214 ? 45.517 93.002 21.301 1.00 16.61 ? 214 TYR A C 1 ATOM 1678 O O . TYR A 1 214 ? 44.386 93.552 21.200 1.00 16.85 ? 214 TYR A O 1 ATOM 1679 C CB . TYR A 1 214 ? 46.243 93.015 23.681 1.00 15.04 ? 214 TYR A CB 1 ATOM 1680 C CG . TYR A 1 214 ? 46.729 92.253 24.859 1.00 15.67 ? 214 TYR A CG 1 ATOM 1681 C CD1 . TYR A 1 214 ? 45.822 91.640 25.727 1.00 15.33 ? 214 TYR A CD1 1 ATOM 1682 C CD2 . TYR A 1 214 ? 48.103 92.131 25.125 1.00 14.96 ? 214 TYR A CD2 1 ATOM 1683 C CE1 . TYR A 1 214 ? 46.266 90.934 26.827 1.00 16.95 ? 214 TYR A CE1 1 ATOM 1684 C CE2 . TYR A 1 214 ? 48.548 91.415 26.215 1.00 13.18 ? 214 TYR A CE2 1 ATOM 1685 C CZ . TYR A 1 214 ? 47.622 90.847 27.081 1.00 14.85 ? 214 TYR A CZ 1 ATOM 1686 O OH . TYR A 1 214 ? 48.036 90.163 28.195 1.00 15.71 ? 214 TYR A OH 1 ATOM 1687 N N . GLY A 1 215 ? 46.478 93.112 20.387 1.00 16.26 ? 215 GLY A N 1 ATOM 1688 C CA . GLY A 1 215 ? 46.370 94.046 19.264 1.00 16.72 ? 215 GLY A CA 1 ATOM 1689 C C . GLY A 1 215 ? 46.602 93.460 17.883 1.00 17.21 ? 215 GLY A C 1 ATOM 1690 O O . GLY A 1 215 ? 47.063 92.313 17.731 1.00 17.04 ? 215 GLY A O 1 ATOM 1691 N N . ALA A 1 216 ? 46.261 94.242 16.863 1.00 17.01 ? 216 ALA A N 1 ATOM 1692 C CA . ALA A 1 216 ? 46.349 93.767 15.482 1.00 16.97 ? 216 ALA A CA 1 ATOM 1693 C C . ALA A 1 216 ? 47.278 94.671 14.672 1.00 16.47 ? 216 ALA A C 1 ATOM 1694 O O . ALA A 1 216 ? 46.969 95.836 14.432 1.00 16.27 ? 216 ALA A O 1 ATOM 1695 C CB . ALA A 1 216 ? 44.971 93.736 14.854 1.00 16.33 ? 216 ALA A CB 1 ATOM 1696 N N . GLN A 1 217 ? 48.404 94.125 14.250 1.00 16.41 ? 217 GLN A N 1 ATOM 1697 C CA . GLN A 1 217 ? 49.409 94.949 13.538 1.00 16.77 ? 217 GLN A CA 1 ATOM 1698 C C . GLN A 1 217 ? 49.936 94.197 12.328 1.00 16.34 ? 217 GLN A C 1 ATOM 1699 O O . GLN A 1 217 ? 50.643 93.236 12.471 1.00 16.95 ? 217 GLN A O 1 ATOM 1700 C CB . GLN A 1 217 ? 50.563 95.309 14.486 1.00 16.96 ? 217 GLN A CB 1 ATOM 1701 C CG . GLN A 1 217 ? 50.174 96.122 15.697 1.00 15.70 ? 217 GLN A CG 1 ATOM 1702 C CD . GLN A 1 217 ? 49.779 97.547 15.362 1.00 15.57 ? 217 GLN A CD 1 ATOM 1703 O OE1 . GLN A 1 217 ? 50.145 98.089 14.302 1.00 17.75 ? 217 GLN A OE1 1 ATOM 1704 N NE2 . GLN A 1 217 ? 49.041 98.182 16.273 1.00 13.51 ? 217 GLN A NE2 1 ATOM 1705 N N . THR A 1 218 ? 49.581 94.625 11.131 1.00 17.42 ? 218 THR A N 1 ATOM 1706 C CA . THR A 1 218 ? 49.954 93.852 9.949 1.00 18.35 ? 218 THR A CA 1 ATOM 1707 C C . THR A 1 218 ? 51.256 94.317 9.308 1.00 19.38 ? 218 THR A C 1 ATOM 1708 O O . THR A 1 218 ? 51.757 93.665 8.396 1.00 20.66 ? 218 THR A O 1 ATOM 1709 C CB . THR A 1 218 ? 48.862 93.829 8.891 1.00 18.91 ? 218 THR A CB 1 ATOM 1710 O OG1 . THR A 1 218 ? 48.646 95.158 8.393 1.00 18.98 ? 218 THR A OG1 1 ATOM 1711 C CG2 . THR A 1 218 ? 47.525 93.226 9.462 1.00 17.06 ? 218 THR A CG2 1 ATOM 1712 N N . PHE A 1 219 ? 51.818 95.413 9.811 1.00 18.71 ? 219 PHE A N 1 ATOM 1713 C CA . PHE A 1 219 ? 53.046 95.985 9.232 1.00 17.87 ? 219 PHE A CA 1 ATOM 1714 C C . PHE A 1 219 ? 54.274 95.128 9.460 1.00 17.61 ? 219 PHE A C 1 ATOM 1715 O O . PHE A 1 219 ? 54.474 94.593 10.558 1.00 16.49 ? 219 PHE A O 1 ATOM 1716 C CB . PHE A 1 219 ? 53.292 97.361 9.813 1.00 18.01 ? 219 PHE A CB 1 ATOM 1717 C CG . PHE A 1 219 ? 54.595 98.012 9.351 1.00 16.73 ? 219 PHE A CG 1 ATOM 1718 C CD1 . PHE A 1 219 ? 54.706 98.531 8.043 1.00 18.16 ? 219 PHE A CD1 1 ATOM 1719 C CD2 . PHE A 1 219 ? 55.667 98.138 10.208 1.00 17.39 ? 219 PHE A CD2 1 ATOM 1720 C CE1 . PHE A 1 219 ? 55.867 99.161 7.607 1.00 17.21 ? 219 PHE A CE1 1 ATOM 1721 C CE2 . PHE A 1 219 ? 56.872 98.762 9.750 1.00 17.02 ? 219 PHE A CE2 1 ATOM 1722 C CZ . PHE A 1 219 ? 56.935 99.281 8.451 1.00 15.79 ? 219 PHE A CZ 1 ATOM 1723 N N . PHE A 1 220 ? 55.089 94.992 8.407 1.00 17.84 ? 220 PHE A N 1 ATOM 1724 C CA . PHE A 1 220 ? 56.437 94.458 8.539 1.00 17.56 ? 220 PHE A CA 1 ATOM 1725 C C . PHE A 1 220 ? 57.446 95.265 7.701 1.00 18.11 ? 220 PHE A C 1 ATOM 1726 O O . PHE A 1 220 ? 57.103 95.850 6.665 1.00 18.77 ? 220 PHE A O 1 ATOM 1727 C CB . PHE A 1 220 ? 56.514 92.956 8.234 1.00 18.41 ? 220 PHE A CB 1 ATOM 1728 C CG . PHE A 1 220 ? 56.462 92.608 6.767 1.00 18.97 ? 220 PHE A CG 1 ATOM 1729 C CD1 . PHE A 1 220 ? 57.604 92.680 5.962 1.00 18.47 ? 220 PHE A CD1 1 ATOM 1730 C CD2 . PHE A 1 220 ? 55.269 92.198 6.182 1.00 21.24 ? 220 PHE A CD2 1 ATOM 1731 C CE1 . PHE A 1 220 ? 57.557 92.366 4.608 1.00 20.38 ? 220 PHE A CE1 1 ATOM 1732 C CE2 . PHE A 1 220 ? 55.209 91.879 4.828 1.00 19.41 ? 220 PHE A CE2 1 ATOM 1733 C CZ . PHE A 1 220 ? 56.356 91.958 4.035 1.00 19.88 ? 220 PHE A CZ 1 ATOM 1734 N N . LEU A 1 221 ? 58.674 95.321 8.184 1.00 17.44 ? 221 LEU A N 1 ATOM 1735 C CA . LEU A 1 221 ? 59.763 95.997 7.485 1.00 17.05 ? 221 LEU A CA 1 ATOM 1736 C C . LEU A 1 221 ? 60.740 94.922 7.011 1.00 16.96 ? 221 LEU A C 1 ATOM 1737 O O . LEU A 1 221 ? 60.956 93.934 7.702 1.00 17.50 ? 221 LEU A O 1 ATOM 1738 C CB . LEU A 1 221 ? 60.454 96.949 8.478 1.00 15.84 ? 221 LEU A CB 1 ATOM 1739 C CG . LEU A 1 221 ? 61.616 97.881 8.071 1.00 17.56 ? 221 LEU A CG 1 ATOM 1740 C CD1 . LEU A 1 221 ? 61.624 99.108 8.985 1.00 14.89 ? 221 LEU A CD1 1 ATOM 1741 C CD2 . LEU A 1 221 ? 62.881 97.147 8.230 1.00 15.55 ? 221 LEU A CD2 1 ATOM 1742 N N . CYS A 1 222 ? 61.357 95.111 5.849 1.00 17.11 ? 222 CYS A N 1 ATOM 1743 C CA . CYS A 1 222 ? 62.378 94.163 5.401 1.00 16.16 ? 222 CYS A CA 1 ATOM 1744 C C . CYS A 1 222 ? 63.666 94.962 5.046 1.00 15.49 ? 222 CYS A C 1 ATOM 1745 O O . CYS A 1 222 ? 63.620 95.901 4.268 1.00 15.02 ? 222 CYS A O 1 ATOM 1746 C CB . CYS A 1 222 ? 61.856 93.368 4.183 1.00 15.27 ? 222 CYS A CB 1 ATOM 1747 S SG . CYS A 1 222 ? 63.088 92.323 3.307 1.00 18.91 ? 222 CYS A SG 1 ATOM 1748 N N . LEU A 1 223 ? 64.788 94.595 5.644 1.00 16.42 ? 223 LEU A N 1 ATOM 1749 C CA . LEU A 1 223 ? 66.087 95.194 5.273 1.00 16.16 ? 223 LEU A CA 1 ATOM 1750 C C . LEU A 1 223 ? 66.625 94.377 4.112 1.00 17.60 ? 223 LEU A C 1 ATOM 1751 O O . LEU A 1 223 ? 66.908 93.192 4.278 1.00 17.15 ? 223 LEU A O 1 ATOM 1752 C CB . LEU A 1 223 ? 67.073 95.182 6.459 1.00 16.13 ? 223 LEU A CB 1 ATOM 1753 C CG . LEU A 1 223 ? 68.566 95.471 6.155 1.00 15.65 ? 223 LEU A CG 1 ATOM 1754 C CD1 . LEU A 1 223 ? 68.718 96.875 5.554 1.00 13.62 ? 223 LEU A CD1 1 ATOM 1755 C CD2 . LEU A 1 223 ? 69.444 95.269 7.393 1.00 15.05 ? 223 LEU A CD2 1 ATOM 1756 N N . GLU A 1 224 ? 66.762 94.998 2.940 1.00 18.61 ? 224 GLU A N 1 ATOM 1757 C CA . GLU A 1 224 ? 67.061 94.253 1.707 1.00 21.13 ? 224 GLU A CA 1 ATOM 1758 C C . GLU A 1 224 ? 68.499 93.754 1.633 1.00 21.81 ? 224 GLU A C 1 ATOM 1759 O O . GLU A 1 224 ? 68.750 92.648 1.174 1.00 21.99 ? 224 GLU A O 1 ATOM 1760 C CB . GLU A 1 224 ? 66.767 95.118 0.465 1.00 21.03 ? 224 GLU A CB 1 ATOM 1761 C CG . GLU A 1 224 ? 65.325 95.524 0.316 1.00 21.81 ? 224 GLU A CG 1 ATOM 1762 C CD . GLU A 1 224 ? 65.122 96.721 -0.623 1.00 23.14 ? 224 GLU A CD 1 ATOM 1763 O OE1 . GLU A 1 224 ? 65.824 96.881 -1.669 1.00 25.33 ? 224 GLU A OE1 1 ATOM 1764 O OE2 . GLU A 1 224 ? 64.235 97.523 -0.294 1.00 25.09 ? 224 GLU A OE2 1 ATOM 1765 N N . ASP A 1 225 ? 69.440 94.596 2.064 1.00 23.02 ? 225 ASP A N 1 ATOM 1766 C CA . ASP A 1 225 ? 70.885 94.316 1.981 1.00 22.36 ? 225 ASP A CA 1 ATOM 1767 C C . ASP A 1 225 ? 71.662 95.275 2.895 1.00 22.58 ? 225 ASP A C 1 ATOM 1768 O O . ASP A 1 225 ? 71.067 96.195 3.517 1.00 20.00 ? 225 ASP A O 1 ATOM 1769 C CB . ASP A 1 225 ? 71.400 94.408 0.497 1.00 23.41 ? 225 ASP A CB 1 ATOM 1770 C CG . ASP A 1 225 ? 71.115 95.775 -0.174 1.00 25.02 ? 225 ASP A CG 1 ATOM 1771 O OD1 . ASP A 1 225 ? 71.310 96.846 0.478 1.00 28.01 ? 225 ASP A OD1 1 ATOM 1772 O OD2 . ASP A 1 225 ? 70.673 95.799 -1.365 1.00 25.33 ? 225 ASP A OD2 1 ATOM 1773 N N . ALA A 1 226 ? 72.991 95.069 2.969 1.00 21.86 ? 226 ALA A N 1 ATOM 1774 C CA . ALA A 1 226 ? 73.897 95.914 3.783 1.00 21.88 ? 226 ALA A CA 1 ATOM 1775 C C . ALA A 1 226 ? 73.887 97.402 3.409 1.00 22.11 ? 226 ALA A C 1 ATOM 1776 O O . ALA A 1 226 ? 74.263 98.246 4.224 1.00 23.69 ? 226 ALA A O 1 ATOM 1777 C CB . ALA A 1 226 ? 75.367 95.364 3.720 1.00 20.99 ? 226 ALA A CB 1 ATOM 1778 N N . SER A 1 227 ? 73.496 97.754 2.185 1.00 21.00 ? 227 SER A N 1 ATOM 1779 C CA . SER A 1 227 ? 73.479 99.169 1.828 1.00 21.45 ? 227 SER A CA 1 ATOM 1780 C C . SER A 1 227 ? 72.423 99.959 2.632 1.00 20.44 ? 227 SER A C 1 ATOM 1781 O O . SER A 1 227 ? 72.473 101.171 2.674 1.00 20.57 ? 227 SER A O 1 ATOM 1782 C CB . SER A 1 227 ? 73.246 99.377 0.339 1.00 21.92 ? 227 SER A CB 1 ATOM 1783 O OG . SER A 1 227 ? 71.879 99.139 0.019 1.00 24.61 ? 227 SER A OG 1 ATOM 1784 N N . GLY A 1 228 ? 71.489 99.266 3.279 1.00 19.81 ? 228 GLY A N 1 ATOM 1785 C CA . GLY A 1 228 ? 70.430 99.949 4.065 1.00 18.92 ? 228 GLY A CA 1 ATOM 1786 C C . GLY A 1 228 ? 69.102 99.966 3.367 1.00 17.81 ? 228 GLY A C 1 ATOM 1787 O O . GLY A 1 228 ? 68.069 100.200 3.998 1.00 18.35 ? 228 GLY A O 1 ATOM 1788 N N . LEU A 1 229 ? 69.088 99.678 2.069 1.00 17.88 ? 229 LEU A N 1 ATOM 1789 C CA . LEU A 1 229 ? 67.841 99.795 1.286 1.00 17.53 ? 229 LEU A CA 1 ATOM 1790 C C . LEU A 1 229 ? 66.799 98.854 1.924 1.00 17.62 ? 229 LEU A C 1 ATOM 1791 O O . LEU A 1 229 ? 67.121 97.728 2.250 1.00 17.13 ? 229 LEU A O 1 ATOM 1792 C CB . LEU A 1 229 ? 68.077 99.474 -0.199 1.00 17.02 ? 229 LEU A CB 1 ATOM 1793 C CG . LEU A 1 229 ? 69.049 100.406 -0.967 1.00 18.36 ? 229 LEU A CG 1 ATOM 1794 C CD1 . LEU A 1 229 ? 69.294 99.954 -2.389 1.00 18.61 ? 229 LEU A CD1 1 ATOM 1795 C CD2 . LEU A 1 229 ? 68.552 101.812 -1.005 1.00 17.21 ? 229 LEU A CD2 1 ATOM 1796 N N . SER A 1 230 ? 65.576 99.340 2.129 1.00 16.88 ? 230 SER A N 1 ATOM 1797 C CA . SER A 1 230 ? 64.616 98.632 2.925 1.00 16.51 ? 230 SER A CA 1 ATOM 1798 C C . SER A 1 230 ? 63.224 98.950 2.325 1.00 16.76 ? 230 SER A C 1 ATOM 1799 O O . SER A 1 230 ? 63.052 99.944 1.616 1.00 15.25 ? 230 SER A O 1 ATOM 1800 C CB . SER A 1 230 ? 64.716 99.123 4.400 1.00 15.62 ? 230 SER A CB 1 ATOM 1801 O OG . SER A 1 230 ? 65.944 98.748 4.997 1.00 17.66 ? 230 SER A OG 1 ATOM 1802 N N . PHE A 1 231 ? 62.234 98.118 2.629 1.00 16.53 ? 231 PHE A N 1 ATOM 1803 C CA . PHE A 1 231 ? 60.869 98.407 2.203 1.00 16.76 ? 231 PHE A CA 1 ATOM 1804 C C . PHE A 1 231 ? 59.950 97.874 3.322 1.00 17.27 ? 231 PHE A C 1 ATOM 1805 O O . PHE A 1 231 ? 60.413 97.150 4.248 1.00 16.88 ? 231 PHE A O 1 ATOM 1806 C CB . PHE A 1 231 ? 60.542 97.836 0.772 1.00 16.95 ? 231 PHE A CB 1 ATOM 1807 C CG . PHE A 1 231 ? 60.239 96.356 0.745 1.00 16.90 ? 231 PHE A CG 1 ATOM 1808 C CD1 . PHE A 1 231 ? 58.923 95.903 0.652 1.00 20.24 ? 231 PHE A CD1 1 ATOM 1809 C CD2 . PHE A 1 231 ? 61.264 95.411 0.804 1.00 19.81 ? 231 PHE A CD2 1 ATOM 1810 C CE1 . PHE A 1 231 ? 58.634 94.541 0.633 1.00 16.75 ? 231 PHE A CE1 1 ATOM 1811 C CE2 . PHE A 1 231 ? 60.978 94.045 0.794 1.00 18.59 ? 231 PHE A CE2 1 ATOM 1812 C CZ . PHE A 1 231 ? 59.671 93.620 0.731 1.00 19.29 ? 231 PHE A CZ 1 ATOM 1813 N N . GLY A 1 232 ? 58.687 98.303 3.297 1.00 16.45 ? 232 GLY A N 1 ATOM 1814 C CA . GLY A 1 232 ? 57.736 97.782 4.257 1.00 16.33 ? 232 GLY A CA 1 ATOM 1815 C C . GLY A 1 232 ? 56.471 97.447 3.529 1.00 16.36 ? 232 GLY A C 1 ATOM 1816 O O . GLY A 1 232 ? 56.277 97.918 2.387 1.00 15.81 ? 232 GLY A O 1 ATOM 1817 N N . VAL A 1 233 ? 55.610 96.647 4.175 1.00 16.23 ? 233 VAL A N 1 ATOM 1818 C CA . VAL A 1 233 ? 54.314 96.279 3.626 1.00 15.23 ? 233 VAL A CA 1 ATOM 1819 C C . VAL A 1 233 ? 53.281 96.462 4.738 1.00 15.48 ? 233 VAL A C 1 ATOM 1820 O O . VAL A 1 233 ? 53.527 96.094 5.881 1.00 13.26 ? 233 VAL A O 1 ATOM 1821 C CB . VAL A 1 233 ? 54.229 94.787 3.079 1.00 15.87 ? 233 VAL A CB 1 ATOM 1822 C CG1 . VAL A 1 233 ? 52.747 94.430 2.660 1.00 16.23 ? 233 VAL A CG1 1 ATOM 1823 C CG2 . VAL A 1 233 ? 55.140 94.568 1.923 1.00 16.94 ? 233 VAL A CG2 1 ATOM 1824 N N . PHE A 1 234 ? 52.128 97.040 4.387 1.00 14.77 ? 234 PHE A N 1 ATOM 1825 C CA . PHE A 1 234 ? 51.015 97.136 5.328 1.00 15.39 ? 234 PHE A CA 1 ATOM 1826 C C . PHE A 1 234 ? 49.698 96.603 4.675 1.00 15.75 ? 234 PHE A C 1 ATOM 1827 O O . PHE A 1 234 ? 49.396 96.981 3.546 1.00 14.53 ? 234 PHE A O 1 ATOM 1828 C CB . PHE A 1 234 ? 50.841 98.587 5.824 1.00 15.27 ? 234 PHE A CB 1 ATOM 1829 C CG . PHE A 1 234 ? 49.630 98.785 6.681 1.00 16.55 ? 234 PHE A CG 1 ATOM 1830 C CD1 . PHE A 1 234 ? 49.521 98.129 7.909 1.00 15.38 ? 234 PHE A CD1 1 ATOM 1831 C CD2 . PHE A 1 234 ? 48.583 99.622 6.260 1.00 13.24 ? 234 PHE A CD2 1 ATOM 1832 C CE1 . PHE A 1 234 ? 48.372 98.271 8.698 1.00 16.92 ? 234 PHE A CE1 1 ATOM 1833 C CE2 . PHE A 1 234 ? 47.430 99.770 7.059 1.00 17.22 ? 234 PHE A CE2 1 ATOM 1834 C CZ . PHE A 1 234 ? 47.338 99.102 8.287 1.00 13.77 ? 234 PHE A CZ 1 ATOM 1835 N N . LEU A 1 235 ? 48.947 95.739 5.397 1.00 14.78 ? 235 LEU A N 1 ATOM 1836 C CA . LEU A 1 235 ? 47.570 95.349 4.992 1.00 14.93 ? 235 LEU A CA 1 ATOM 1837 C C . LEU A 1 235 ? 46.530 96.035 5.853 1.00 14.52 ? 235 LEU A C 1 ATOM 1838 O O . LEU A 1 235 ? 46.492 95.821 7.055 1.00 13.25 ? 235 LEU A O 1 ATOM 1839 C CB . LEU A 1 235 ? 47.379 93.828 5.104 1.00 14.88 ? 235 LEU A CB 1 ATOM 1840 C CG . LEU A 1 235 ? 46.006 93.244 4.830 1.00 14.26 ? 235 LEU A CG 1 ATOM 1841 C CD1 . LEU A 1 235 ? 45.522 93.639 3.463 1.00 11.80 ? 235 LEU A CD1 1 ATOM 1842 C CD2 . LEU A 1 235 ? 46.014 91.719 4.987 1.00 15.63 ? 235 LEU A CD2 1 ATOM 1843 N N . MET A 1 236 ? 45.701 96.869 5.228 1.00 15.66 ? 236 MET A N 1 ATOM 1844 C CA . MET A 1 236 ? 44.602 97.537 5.881 1.00 16.95 ? 236 MET A CA 1 ATOM 1845 C C . MET A 1 236 ? 43.381 96.601 5.876 1.00 18.67 ? 236 MET A C 1 ATOM 1846 O O . MET A 1 236 ? 42.549 96.623 4.943 1.00 18.49 ? 236 MET A O 1 ATOM 1847 C CB . MET A 1 236 ? 44.307 98.803 5.109 1.00 16.90 ? 236 MET A CB 1 ATOM 1848 C CG . MET A 1 236 ? 43.209 99.672 5.687 1.00 18.60 ? 236 MET A CG 1 ATOM 1849 S SD . MET A 1 236 ? 43.538 100.371 7.302 1.00 22.00 ? 236 MET A SD 1 ATOM 1850 C CE . MET A 1 236 ? 44.209 101.975 6.838 1.00 20.94 ? 236 MET A CE 1 ATOM 1851 N N . ASN A 1 237 ? 43.277 95.769 6.909 1.00 19.24 ? 237 ASN A N 1 ATOM 1852 C CA . ASN A 1 237 ? 42.180 94.788 6.997 1.00 19.74 ? 237 ASN A CA 1 ATOM 1853 C C . ASN A 1 237 ? 42.034 94.446 8.480 1.00 20.05 ? 237 ASN A C 1 ATOM 1854 O O . ASN A 1 237 ? 43.039 94.116 9.135 1.00 20.05 ? 237 ASN A O 1 ATOM 1855 C CB . ASN A 1 237 ? 42.532 93.550 6.128 1.00 19.09 ? 237 ASN A CB 1 ATOM 1856 C CG . ASN A 1 237 ? 41.466 92.458 6.154 1.00 22.39 ? 237 ASN A CG 1 ATOM 1857 O OD1 . ASN A 1 237 ? 41.350 91.743 7.135 1.00 22.32 ? 237 ASN A OD1 1 ATOM 1858 N ND2 . ASN A 1 237 ? 40.741 92.281 5.040 1.00 20.90 ? 237 ASN A ND2 1 ATOM 1859 N N . SER A 1 238 ? 40.810 94.562 9.016 1.00 19.37 ? 238 SER A N 1 ATOM 1860 C CA . SER A 1 238 ? 40.551 94.316 10.430 1.00 19.42 ? 238 SER A CA 1 ATOM 1861 C C . SER A 1 238 ? 39.901 92.952 10.766 1.00 20.28 ? 238 SER A C 1 ATOM 1862 O O . SER A 1 238 ? 39.503 92.709 11.928 1.00 21.47 ? 238 SER A O 1 ATOM 1863 C CB . SER A 1 238 ? 39.708 95.459 11.008 1.00 18.85 ? 238 SER A CB 1 ATOM 1864 O OG . SER A 1 238 ? 38.491 95.642 10.296 1.00 20.57 ? 238 SER A OG 1 ATOM 1865 N N . ASN A 1 239 ? 39.775 92.064 9.773 1.00 19.57 ? 239 ASN A N 1 ATOM 1866 C CA . ASN A 1 239 ? 39.201 90.744 10.007 1.00 19.42 ? 239 ASN A CA 1 ATOM 1867 C C . ASN A 1 239 ? 40.219 89.832 10.657 1.00 19.34 ? 239 ASN A C 1 ATOM 1868 O O . ASN A 1 239 ? 41.415 90.074 10.509 1.00 19.11 ? 239 ASN A O 1 ATOM 1869 C CB . ASN A 1 239 ? 38.703 90.141 8.691 1.00 18.46 ? 239 ASN A CB 1 ATOM 1870 C CG . ASN A 1 239 ? 37.451 90.844 8.179 1.00 20.62 ? 239 ASN A CG 1 ATOM 1871 O OD1 . ASN A 1 239 ? 36.329 90.411 8.448 1.00 25.49 ? 239 ASN A OD1 1 ATOM 1872 N ND2 . ASN A 1 239 ? 37.630 91.949 7.498 1.00 17.25 ? 239 ASN A ND2 1 ATOM 1873 N N . ALA A 1 240 ? 39.759 88.791 11.357 1.00 18.44 ? 240 ALA A N 1 ATOM 1874 C CA . ALA A 1 240 ? 40.663 87.720 11.818 1.00 19.14 ? 240 ALA A CA 1 ATOM 1875 C C . ALA A 1 240 ? 41.532 87.227 10.662 1.00 19.34 ? 240 ALA A C 1 ATOM 1876 O O . ALA A 1 240 ? 41.058 86.998 9.537 1.00 19.19 ? 240 ALA A O 1 ATOM 1877 C CB . ALA A 1 240 ? 39.865 86.510 12.419 1.00 19.16 ? 240 ALA A CB 1 ATOM 1878 N N . MET A 1 241 ? 42.804 87.017 10.935 1.00 18.35 ? 241 MET A N 1 ATOM 1879 C CA . MET A 1 241 ? 43.676 86.680 9.864 1.00 19.30 ? 241 MET A CA 1 ATOM 1880 C C . MET A 1 241 ? 44.859 85.930 10.463 1.00 18.74 ? 241 MET A C 1 ATOM 1881 O O . MET A 1 241 ? 44.993 85.883 11.665 1.00 17.74 ? 241 MET A O 1 ATOM 1882 C CB . MET A 1 241 ? 44.100 87.964 9.158 1.00 18.63 ? 241 MET A CB 1 ATOM 1883 C CG . MET A 1 241 ? 45.302 88.692 9.833 1.00 20.28 ? 241 MET A CG 1 ATOM 1884 S SD . MET A 1 241 ? 45.980 89.966 8.710 1.00 22.47 ? 241 MET A SD 1 ATOM 1885 C CE . MET A 1 241 ? 44.564 91.040 8.677 1.00 15.58 ? 241 MET A CE 1 ATOM 1886 N N . GLU A 1 242 ? 45.658 85.293 9.621 1.00 19.36 ? 242 GLU A N 1 ATOM 1887 C CA . GLU A 1 242 ? 47.002 84.863 10.017 1.00 20.20 ? 242 GLU A CA 1 ATOM 1888 C C . GLU A 1 242 ? 47.983 85.173 8.904 1.00 20.23 ? 242 GLU A C 1 ATOM 1889 O O . GLU A 1 242 ? 47.597 85.364 7.744 1.00 21.67 ? 242 GLU A O 1 ATOM 1890 C CB . GLU A 1 242 ? 47.070 83.383 10.423 1.00 19.88 ? 242 GLU A CB 1 ATOM 1891 C CG . GLU A 1 242 ? 46.739 82.398 9.315 1.00 21.14 ? 242 GLU A CG 1 ATOM 1892 C CD . GLU A 1 242 ? 46.126 81.083 9.872 1.00 28.09 ? 242 GLU A CD 1 ATOM 1893 O OE1 . GLU A 1 242 ? 45.767 81.034 11.074 1.00 29.52 ? 242 GLU A OE1 1 ATOM 1894 O OE2 . GLU A 1 242 ? 46.015 80.099 9.114 1.00 27.58 ? 242 GLU A OE2 1 ATOM 1895 N N . VAL A 1 243 ? 49.249 85.249 9.281 1.00 19.64 ? 243 VAL A N 1 ATOM 1896 C CA . VAL A 1 243 ? 50.345 85.584 8.379 1.00 19.03 ? 243 VAL A CA 1 ATOM 1897 C C . VAL A 1 243 ? 51.290 84.366 8.395 1.00 18.16 ? 243 VAL A C 1 ATOM 1898 O O . VAL A 1 243 ? 51.737 83.927 9.451 1.00 17.52 ? 243 VAL A O 1 ATOM 1899 C CB . VAL A 1 243 ? 51.071 86.849 8.883 1.00 19.46 ? 243 VAL A CB 1 ATOM 1900 C CG1 . VAL A 1 243 ? 52.149 87.309 7.895 1.00 20.78 ? 243 VAL A CG1 1 ATOM 1901 C CG2 . VAL A 1 243 ? 50.079 87.985 9.097 1.00 19.34 ? 243 VAL A CG2 1 ATOM 1902 N N . VAL A 1 244 ? 51.560 83.811 7.223 1.00 17.22 ? 244 VAL A N 1 ATOM 1903 C CA . VAL A 1 244 ? 52.310 82.555 7.099 1.00 16.94 ? 244 VAL A CA 1 ATOM 1904 C C . VAL A 1 244 ? 53.691 82.900 6.535 1.00 17.20 ? 244 VAL A C 1 ATOM 1905 O O . VAL A 1 244 ? 53.778 83.547 5.498 1.00 17.12 ? 244 VAL A O 1 ATOM 1906 C CB . VAL A 1 244 ? 51.545 81.551 6.164 1.00 16.37 ? 244 VAL A CB 1 ATOM 1907 C CG1 . VAL A 1 244 ? 52.229 80.176 6.122 1.00 14.69 ? 244 VAL A CG1 1 ATOM 1908 C CG2 . VAL A 1 244 ? 50.072 81.381 6.671 1.00 15.75 ? 244 VAL A CG2 1 ATOM 1909 N N . LEU A 1 245 ? 54.746 82.459 7.204 1.00 17.19 ? 245 LEU A N 1 ATOM 1910 C CA . LEU A 1 245 ? 56.111 82.779 6.771 1.00 18.23 ? 245 LEU A CA 1 ATOM 1911 C C . LEU A 1 245 ? 56.719 81.481 6.344 1.00 18.06 ? 245 LEU A C 1 ATOM 1912 O O . LEU A 1 245 ? 56.528 80.471 7.005 1.00 17.38 ? 245 LEU A O 1 ATOM 1913 C CB . LEU A 1 245 ? 56.961 83.388 7.920 1.00 17.88 ? 245 LEU A CB 1 ATOM 1914 C CG . LEU A 1 245 ? 56.390 84.600 8.684 1.00 20.14 ? 245 LEU A CG 1 ATOM 1915 C CD1 . LEU A 1 245 ? 57.436 85.192 9.646 1.00 24.11 ? 245 LEU A CD1 1 ATOM 1916 C CD2 . LEU A 1 245 ? 56.025 85.610 7.743 1.00 20.76 ? 245 LEU A CD2 1 ATOM 1917 N N . GLN A 1 246 ? 57.450 81.483 5.241 1.00 19.18 ? 246 GLN A N 1 ATOM 1918 C CA . GLN A 1 246 ? 58.154 80.250 4.819 1.00 19.10 ? 246 GLN A CA 1 ATOM 1919 C C . GLN A 1 246 ? 59.511 80.565 4.191 1.00 18.65 ? 246 GLN A C 1 ATOM 1920 O O . GLN A 1 246 ? 59.720 81.706 3.839 1.00 18.02 ? 246 GLN A O 1 ATOM 1921 C CB . GLN A 1 246 ? 57.268 79.468 3.876 1.00 18.42 ? 246 GLN A CB 1 ATOM 1922 C CG . GLN A 1 246 ? 57.006 80.135 2.569 1.00 19.39 ? 246 GLN A CG 1 ATOM 1923 C CD . GLN A 1 246 ? 55.888 79.414 1.862 1.00 20.80 ? 246 GLN A CD 1 ATOM 1924 O OE1 . GLN A 1 246 ? 54.710 79.605 2.182 1.00 20.12 ? 246 GLN A OE1 1 ATOM 1925 N NE2 . GLN A 1 246 ? 56.246 78.555 0.934 1.00 18.98 ? 246 GLN A NE2 1 ATOM 1926 N N . PRO A 1 247 ? 60.448 79.568 4.117 1.00 19.77 ? 247 PRO A N 1 ATOM 1927 C CA . PRO A 1 247 ? 61.851 79.816 3.766 1.00 20.27 ? 247 PRO A CA 1 ATOM 1928 C C . PRO A 1 247 ? 62.211 80.096 2.317 1.00 20.97 ? 247 PRO A C 1 ATOM 1929 O O . PRO A 1 247 ? 63.393 80.132 2.004 1.00 22.84 ? 247 PRO A O 1 ATOM 1930 C CB . PRO A 1 247 ? 62.589 78.559 4.257 1.00 20.04 ? 247 PRO A CB 1 ATOM 1931 C CG . PRO A 1 247 ? 61.601 77.650 4.761 1.00 20.37 ? 247 PRO A CG 1 ATOM 1932 C CD . PRO A 1 247 ? 60.236 78.166 4.498 1.00 20.15 ? 247 PRO A CD 1 ATOM 1933 N N . ALA A 1 248 ? 61.220 80.331 1.462 1.00 21.39 ? 248 ALA A N 1 ATOM 1934 C CA . ALA A 1 248 ? 61.453 80.667 0.074 1.00 21.44 ? 248 ALA A CA 1 ATOM 1935 C C . ALA A 1 248 ? 62.524 81.773 -0.143 1.00 21.87 ? 248 ALA A C 1 ATOM 1936 O O . ALA A 1 248 ? 63.365 81.577 -0.988 1.00 23.29 ? 248 ALA A O 1 ATOM 1937 C CB . ALA A 1 248 ? 60.162 80.982 -0.642 1.00 20.77 ? 248 ALA A CB 1 ATOM 1938 N N . PRO A 1 249 ? 62.517 82.906 0.636 1.00 20.88 ? 249 PRO A N 1 ATOM 1939 C CA . PRO A 1 249 ? 61.552 83.373 1.657 1.00 19.54 ? 249 PRO A CA 1 ATOM 1940 C C . PRO A 1 249 ? 60.271 83.974 1.105 1.00 19.17 ? 249 PRO A C 1 ATOM 1941 O O . PRO A 1 249 ? 60.238 84.527 0.016 1.00 19.74 ? 249 PRO A O 1 ATOM 1942 C CB . PRO A 1 249 ? 62.332 84.419 2.451 1.00 19.46 ? 249 PRO A CB 1 ATOM 1943 C CG . PRO A 1 249 ? 63.364 84.949 1.467 1.00 20.52 ? 249 PRO A CG 1 ATOM 1944 C CD . PRO A 1 249 ? 63.690 83.810 0.521 1.00 20.48 ? 249 PRO A CD 1 ATOM 1945 N N . ALA A 1 250 ? 59.210 83.878 1.866 1.00 18.82 ? 250 ALA A N 1 ATOM 1946 C CA . ALA A 1 250 ? 57.930 84.429 1.401 1.00 18.33 ? 250 ALA A CA 1 ATOM 1947 C C . ALA A 1 250 ? 57.017 84.610 2.589 1.00 18.06 ? 250 ALA A C 1 ATOM 1948 O O . ALA A 1 250 ? 57.215 83.974 3.612 1.00 18.12 ? 250 ALA A O 1 ATOM 1949 C CB . ALA A 1 250 ? 57.285 83.472 0.384 1.00 17.22 ? 250 ALA A CB 1 ATOM 1950 N N . ILE A 1 251 ? 56.011 85.462 2.427 1.00 18.45 ? 251 ILE A N 1 ATOM 1951 C CA . ILE A 1 251 ? 55.017 85.729 3.430 1.00 19.44 ? 251 ILE A CA 1 ATOM 1952 C C . ILE A 1 251 ? 53.653 85.692 2.769 1.00 19.05 ? 251 ILE A C 1 ATOM 1953 O O . ILE A 1 251 ? 53.465 86.236 1.671 1.00 18.90 ? 251 ILE A O 1 ATOM 1954 C CB . ILE A 1 251 ? 55.305 87.072 4.109 1.00 20.38 ? 251 ILE A CB 1 ATOM 1955 C CG1 . ILE A 1 251 ? 54.233 87.476 5.090 1.00 23.34 ? 251 ILE A CG1 1 ATOM 1956 C CG2 . ILE A 1 251 ? 55.410 88.195 3.109 1.00 23.04 ? 251 ILE A CG2 1 ATOM 1957 C CD1 . ILE A 1 251 ? 54.852 88.418 6.174 1.00 29.41 ? 251 ILE A CD1 1 ATOM 1958 N N . THR A 1 252 ? 52.716 84.982 3.402 1.00 18.74 ? 252 THR A N 1 ATOM 1959 C CA . THR A 1 252 ? 51.301 84.955 2.949 1.00 19.14 ? 252 THR A CA 1 ATOM 1960 C C . THR A 1 252 ? 50.408 85.617 3.992 1.00 18.78 ? 252 THR A C 1 ATOM 1961 O O . THR A 1 252 ? 50.580 85.354 5.164 1.00 19.59 ? 252 THR A O 1 ATOM 1962 C CB . THR A 1 252 ? 50.840 83.496 2.705 1.00 18.04 ? 252 THR A CB 1 ATOM 1963 O OG1 . THR A 1 252 ? 51.690 82.902 1.719 1.00 21.14 ? 252 THR A OG1 1 ATOM 1964 C CG2 . THR A 1 252 ? 49.428 83.435 2.207 1.00 18.70 ? 252 THR A CG2 1 ATOM 1965 N N . TYR A 1 253 ? 49.503 86.497 3.560 1.00 19.02 ? 253 TYR A N 1 ATOM 1966 C CA . TYR A 1 253 ? 48.420 87.026 4.385 1.00 19.53 ? 253 TYR A CA 1 ATOM 1967 C C . TYR A 1 253 ? 47.143 86.226 4.060 1.00 19.60 ? 253 TYR A C 1 ATOM 1968 O O . TYR A 1 253 ? 46.744 86.106 2.884 1.00 17.92 ? 253 TYR A O 1 ATOM 1969 C CB . TYR A 1 253 ? 48.160 88.503 4.068 1.00 21.93 ? 253 TYR A CB 1 ATOM 1970 C CG . TYR A 1 253 ? 49.224 89.498 4.551 1.00 21.85 ? 253 TYR A CG 1 ATOM 1971 C CD1 . TYR A 1 253 ? 49.161 90.037 5.820 1.00 24.89 ? 253 TYR A CD1 1 ATOM 1972 C CD2 . TYR A 1 253 ? 50.271 89.900 3.725 1.00 25.29 ? 253 TYR A CD2 1 ATOM 1973 C CE1 . TYR A 1 253 ? 50.128 90.949 6.285 1.00 24.26 ? 253 TYR A CE1 1 ATOM 1974 C CE2 . TYR A 1 253 ? 51.255 90.828 4.177 1.00 24.58 ? 253 TYR A CE2 1 ATOM 1975 C CZ . TYR A 1 253 ? 51.156 91.349 5.456 1.00 26.47 ? 253 TYR A CZ 1 ATOM 1976 O OH . TYR A 1 253 ? 52.101 92.282 5.927 1.00 28.78 ? 253 TYR A OH 1 ATOM 1977 N N . ARG A 1 254 ? 46.516 85.665 5.087 1.00 18.79 ? 254 ARG A N 1 ATOM 1978 C CA . ARG A 1 254 ? 45.296 84.860 4.886 1.00 19.28 ? 254 ARG A CA 1 ATOM 1979 C C . ARG A 1 254 ? 44.183 85.405 5.782 1.00 18.60 ? 254 ARG A C 1 ATOM 1980 O O . ARG A 1 254 ? 44.242 85.259 6.968 1.00 19.48 ? 254 ARG A O 1 ATOM 1981 C CB . ARG A 1 254 ? 45.652 83.420 5.245 1.00 19.18 ? 254 ARG A CB 1 ATOM 1982 C CG . ARG A 1 254 ? 44.585 82.350 5.006 1.00 20.71 ? 254 ARG A CG 1 ATOM 1983 C CD . ARG A 1 254 ? 45.113 81.064 5.670 1.00 17.58 ? 254 ARG A CD 1 ATOM 1984 N NE . ARG A 1 254 ? 46.163 80.454 4.870 1.00 16.70 ? 254 ARG A NE 1 ATOM 1985 C CZ . ARG A 1 254 ? 47.126 79.693 5.371 1.00 16.39 ? 254 ARG A CZ 1 ATOM 1986 N NH1 . ARG A 1 254 ? 47.180 79.441 6.680 1.00 19.66 ? 254 ARG A NH1 1 ATOM 1987 N NH2 . ARG A 1 254 ? 48.022 79.167 4.563 1.00 16.03 ? 254 ARG A NH2 1 ATOM 1988 N N . THR A 1 255 ? 43.183 86.075 5.227 1.00 19.30 ? 255 THR A N 1 ATOM 1989 C CA . THR A 1 255 ? 42.165 86.729 6.062 1.00 18.03 ? 255 THR A CA 1 ATOM 1990 C C . THR A 1 255 ? 40.747 86.193 5.769 1.00 18.56 ? 255 THR A C 1 ATOM 1991 O O . THR A 1 255 ? 40.544 85.555 4.737 1.00 17.96 ? 255 THR A O 1 ATOM 1992 C CB . THR A 1 255 ? 42.211 88.275 5.914 1.00 17.85 ? 255 THR A CB 1 ATOM 1993 O OG1 . THR A 1 255 ? 41.310 88.853 6.866 1.00 21.01 ? 255 THR A OG1 1 ATOM 1994 C CG2 . THR A 1 255 ? 41.795 88.747 4.548 1.00 17.51 ? 255 THR A CG2 1 ATOM 1995 N N . ILE A 1 256 ? 39.776 86.459 6.661 1.00 17.96 ? 256 ILE A N 1 ATOM 1996 C CA . ILE A 1 256 ? 38.445 85.830 6.518 1.00 18.19 ? 256 ILE A CA 1 ATOM 1997 C C . ILE A 1 256 ? 37.322 86.816 6.234 1.00 18.22 ? 256 ILE A C 1 ATOM 1998 O O . ILE A 1 256 ? 36.139 86.497 6.393 1.00 19.22 ? 256 ILE A O 1 ATOM 1999 C CB . ILE A 1 256 ? 38.108 84.842 7.712 1.00 18.63 ? 256 ILE A CB 1 ATOM 2000 C CG1 . ILE A 1 256 ? 37.953 85.558 9.047 1.00 17.34 ? 256 ILE A CG1 1 ATOM 2001 C CG2 . ILE A 1 256 ? 39.188 83.766 7.856 1.00 16.15 ? 256 ILE A CG2 1 ATOM 2002 C CD1 . ILE A 1 256 ? 37.310 84.623 10.161 1.00 18.93 ? 256 ILE A CD1 1 ATOM 2003 N N . GLY A 1 257 ? 37.683 88.031 5.851 1.00 16.97 ? 257 GLY A N 1 ATOM 2004 C CA . GLY A 1 257 ? 36.681 88.965 5.357 1.00 18.05 ? 257 GLY A CA 1 ATOM 2005 C C . GLY A 1 257 ? 37.344 90.202 4.827 1.00 18.47 ? 257 GLY A C 1 ATOM 2006 O O . GLY A 1 257 ? 38.585 90.243 4.707 1.00 17.51 ? 257 GLY A O 1 ATOM 2007 N N . GLY A 1 258 ? 36.524 91.217 4.561 1.00 18.32 ? 258 GLY A N 1 ATOM 2008 C CA . GLY A 1 258 ? 37.011 92.500 4.096 1.00 18.77 ? 258 GLY A CA 1 ATOM 2009 C C . GLY A 1 258 ? 37.561 92.393 2.689 1.00 20.36 ? 258 GLY A C 1 ATOM 2010 O O . GLY A 1 258 ? 37.034 91.634 1.832 1.00 20.10 ? 258 GLY A O 1 ATOM 2011 N N . ILE A 1 259 ? 38.613 93.168 2.429 1.00 19.84 ? 259 ILE A N 1 ATOM 2012 C CA . ILE A 1 259 ? 39.232 93.206 1.110 1.00 19.80 ? 259 ILE A CA 1 ATOM 2013 C C . ILE A 1 259 ? 40.755 93.265 1.319 1.00 20.48 ? 259 ILE A C 1 ATOM 2014 O O . ILE A 1 259 ? 41.223 93.560 2.420 1.00 21.14 ? 259 ILE A O 1 ATOM 2015 C CB . ILE A 1 259 ? 38.815 94.469 0.313 1.00 20.24 ? 259 ILE A CB 1 ATOM 2016 C CG1 . ILE A 1 259 ? 39.246 95.757 1.034 1.00 18.62 ? 259 ILE A CG1 1 ATOM 2017 C CG2 . ILE A 1 259 ? 37.298 94.457 -0.015 1.00 18.75 ? 259 ILE A CG2 1 ATOM 2018 C CD1 . ILE A 1 259 ? 39.337 96.971 0.111 1.00 17.29 ? 259 ILE A CD1 1 ATOM 2019 N N . LEU A 1 260 ? 41.513 92.972 0.269 1.00 19.64 ? 260 LEU A N 1 ATOM 2020 C CA . LEU A 1 260 ? 42.956 92.997 0.341 1.00 20.45 ? 260 LEU A CA 1 ATOM 2021 C C . LEU A 1 260 ? 43.395 94.391 -0.102 1.00 20.52 ? 260 LEU A C 1 ATOM 2022 O O . LEU A 1 260 ? 43.357 94.727 -1.284 1.00 22.74 ? 260 LEU A O 1 ATOM 2023 C CB . LEU A 1 260 ? 43.553 91.909 -0.556 1.00 19.47 ? 260 LEU A CB 1 ATOM 2024 C CG . LEU A 1 260 ? 43.337 90.451 -0.135 1.00 21.18 ? 260 LEU A CG 1 ATOM 2025 C CD1 . LEU A 1 260 ? 43.783 89.494 -1.222 1.00 17.04 ? 260 LEU A CD1 1 ATOM 2026 C CD2 . LEU A 1 260 ? 44.028 90.109 1.203 1.00 20.76 ? 260 LEU A CD2 1 ATOM 2027 N N . ASP A 1 261 ? 43.738 95.223 0.864 1.00 20.63 ? 261 ASP A N 1 ATOM 2028 C CA . ASP A 1 261 ? 44.020 96.631 0.618 1.00 20.59 ? 261 ASP A CA 1 ATOM 2029 C C . ASP A 1 261 ? 45.460 96.871 1.096 1.00 20.27 ? 261 ASP A C 1 ATOM 2030 O O . ASP A 1 261 ? 45.688 96.969 2.306 1.00 20.05 ? 261 ASP A O 1 ATOM 2031 C CB . ASP A 1 261 ? 42.993 97.490 1.388 1.00 20.37 ? 261 ASP A CB 1 ATOM 2032 C CG . ASP A 1 261 ? 43.276 98.970 1.309 1.00 22.17 ? 261 ASP A CG 1 ATOM 2033 O OD1 . ASP A 1 261 ? 44.302 99.336 0.709 1.00 28.54 ? 261 ASP A OD1 1 ATOM 2034 O OD2 . ASP A 1 261 ? 42.471 99.791 1.817 1.00 24.05 ? 261 ASP A OD2 1 ATOM 2035 N N . PHE A 1 262 ? 46.403 96.915 0.150 1.00 19.26 ? 262 PHE A N 1 ATOM 2036 C CA . PHE A 1 262 ? 47.853 96.835 0.437 1.00 19.49 ? 262 PHE A CA 1 ATOM 2037 C C . PHE A 1 262 ? 48.596 98.168 0.168 1.00 18.48 ? 262 PHE A C 1 ATOM 2038 O O . PHE A 1 262 ? 48.251 98.926 -0.760 1.00 18.35 ? 262 PHE A O 1 ATOM 2039 C CB . PHE A 1 262 ? 48.516 95.745 -0.420 1.00 18.68 ? 262 PHE A CB 1 ATOM 2040 C CG . PHE A 1 262 ? 48.420 94.348 0.152 1.00 20.01 ? 262 PHE A CG 1 ATOM 2041 C CD1 . PHE A 1 262 ? 49.235 93.961 1.226 1.00 19.04 ? 262 PHE A CD1 1 ATOM 2042 C CD2 . PHE A 1 262 ? 47.539 93.409 -0.392 1.00 19.30 ? 262 PHE A CD2 1 ATOM 2043 C CE1 . PHE A 1 262 ? 49.160 92.673 1.758 1.00 21.07 ? 262 PHE A CE1 1 ATOM 2044 C CE2 . PHE A 1 262 ? 47.462 92.098 0.132 1.00 19.69 ? 262 PHE A CE2 1 ATOM 2045 C CZ . PHE A 1 262 ? 48.260 91.733 1.208 1.00 20.13 ? 262 PHE A CZ 1 ATOM 2046 N N . TYR A 1 263 ? 49.594 98.436 0.997 1.00 18.09 ? 263 TYR A N 1 ATOM 2047 C CA . TYR A 1 263 ? 50.523 99.553 0.798 1.00 17.74 ? 263 TYR A CA 1 ATOM 2048 C C . TYR A 1 263 ? 51.946 98.971 0.761 1.00 18.05 ? 263 TYR A C 1 ATOM 2049 O O . TYR A 1 263 ? 52.277 98.061 1.527 1.00 17.53 ? 263 TYR A O 1 ATOM 2050 C CB . TYR A 1 263 ? 50.421 100.562 1.945 1.00 17.22 ? 263 TYR A CB 1 ATOM 2051 C CG . TYR A 1 263 ? 49.103 101.316 1.971 1.00 19.91 ? 263 TYR A CG 1 ATOM 2052 C CD1 . TYR A 1 263 ? 48.966 102.529 1.293 1.00 17.97 ? 263 TYR A CD1 1 ATOM 2053 C CD2 . TYR A 1 263 ? 47.998 100.806 2.658 1.00 17.71 ? 263 TYR A CD2 1 ATOM 2054 C CE1 . TYR A 1 263 ? 47.797 103.233 1.314 1.00 18.85 ? 263 TYR A CE1 1 ATOM 2055 C CE2 . TYR A 1 263 ? 46.795 101.510 2.690 1.00 22.14 ? 263 TYR A CE2 1 ATOM 2056 C CZ . TYR A 1 263 ? 46.702 102.713 2.010 1.00 21.44 ? 263 TYR A CZ 1 ATOM 2057 O OH . TYR A 1 263 ? 45.528 103.414 2.037 1.00 21.00 ? 263 TYR A OH 1 ATOM 2058 N N . VAL A 1 264 ? 52.778 99.482 -0.139 1.00 16.80 ? 264 VAL A N 1 ATOM 2059 C CA . VAL A 1 264 ? 54.158 99.079 -0.175 1.00 16.27 ? 264 VAL A CA 1 ATOM 2060 C C . VAL A 1 264 ? 54.978 100.399 -0.049 1.00 16.21 ? 264 VAL A C 1 ATOM 2061 O O . VAL A 1 264 ? 54.709 101.368 -0.769 1.00 15.93 ? 264 VAL A O 1 ATOM 2062 C CB . VAL A 1 264 ? 54.508 98.216 -1.446 1.00 16.35 ? 264 VAL A CB 1 ATOM 2063 C CG1 . VAL A 1 264 ? 55.992 97.793 -1.463 1.00 16.92 ? 264 VAL A CG1 1 ATOM 2064 C CG2 . VAL A 1 264 ? 53.591 96.947 -1.556 1.00 17.18 ? 264 VAL A CG2 1 ATOM 2065 N N . PHE A 1 265 ? 55.942 100.425 0.884 1.00 16.05 ? 265 PHE A N 1 ATOM 2066 C CA . PHE A 1 265 ? 56.715 101.652 1.244 1.00 15.82 ? 265 PHE A CA 1 ATOM 2067 C C . PHE A 1 265 ? 58.175 101.335 0.940 1.00 16.23 ? 265 PHE A C 1 ATOM 2068 O O . PHE A 1 265 ? 58.600 100.238 1.269 1.00 16.06 ? 265 PHE A O 1 ATOM 2069 C CB . PHE A 1 265 ? 56.593 101.982 2.768 1.00 15.09 ? 265 PHE A CB 1 ATOM 2070 C CG . PHE A 1 265 ? 55.149 101.994 3.308 1.00 17.33 ? 265 PHE A CG 1 ATOM 2071 C CD1 . PHE A 1 265 ? 54.342 103.116 3.137 1.00 15.15 ? 265 PHE A CD1 1 ATOM 2072 C CD2 . PHE A 1 265 ? 54.634 100.887 4.010 1.00 15.60 ? 265 PHE A CD2 1 ATOM 2073 C CE1 . PHE A 1 265 ? 53.013 103.146 3.622 1.00 14.63 ? 265 PHE A CE1 1 ATOM 2074 C CE2 . PHE A 1 265 ? 53.312 100.894 4.482 1.00 16.40 ? 265 PHE A CE2 1 ATOM 2075 C CZ . PHE A 1 265 ? 52.506 102.037 4.299 1.00 11.54 ? 265 PHE A CZ 1 ATOM 2076 N N . LEU A 1 266 ? 58.914 102.263 0.310 1.00 16.55 ? 266 LEU A N 1 ATOM 2077 C CA . LEU A 1 266 ? 60.360 102.098 0.060 1.00 17.73 ? 266 LEU A CA 1 ATOM 2078 C C . LEU A 1 266 ? 61.154 103.169 0.797 1.00 17.84 ? 266 LEU A C 1 ATOM 2079 O O . LEU A 1 266 ? 60.668 104.273 0.962 1.00 17.93 ? 266 LEU A O 1 ATOM 2080 C CB . LEU A 1 266 ? 60.684 102.206 -1.443 1.00 17.24 ? 266 LEU A CB 1 ATOM 2081 C CG . LEU A 1 266 ? 60.404 101.028 -2.381 1.00 18.71 ? 266 LEU A CG 1 ATOM 2082 C CD1 . LEU A 1 266 ? 58.886 100.829 -2.599 1.00 18.22 ? 266 LEU A CD1 1 ATOM 2083 C CD2 . LEU A 1 266 ? 61.120 101.262 -3.721 1.00 17.30 ? 266 LEU A CD2 1 ATOM 2084 N N . GLY A 1 267 ? 62.379 102.833 1.206 1.00 18.59 ? 267 GLY A N 1 ATOM 2085 C CA . GLY A 1 267 ? 63.261 103.748 1.880 1.00 17.65 ? 267 GLY A CA 1 ATOM 2086 C C . GLY A 1 267 ? 64.740 103.437 1.645 1.00 18.02 ? 267 GLY A C 1 ATOM 2087 O O . GLY A 1 267 ? 65.140 102.301 1.276 1.00 16.94 ? 267 GLY A O 1 ATOM 2088 N N . ASN A 1 268 ? 65.566 104.449 1.866 1.00 17.81 ? 268 ASN A N 1 ATOM 2089 C CA . ASN A 1 268 ? 67.023 104.253 1.759 1.00 18.61 ? 268 ASN A CA 1 ATOM 2090 C C . ASN A 1 268 ? 67.626 103.553 2.967 1.00 17.76 ? 268 ASN A C 1 ATOM 2091 O O . ASN A 1 268 ? 68.721 102.991 2.890 1.00 18.35 ? 268 ASN A O 1 ATOM 2092 C CB . ASN A 1 268 ? 67.730 105.593 1.451 1.00 19.01 ? 268 ASN A CB 1 ATOM 2093 C CG . ASN A 1 268 ? 67.398 106.109 0.055 1.00 22.66 ? 268 ASN A CG 1 ATOM 2094 O OD1 . ASN A 1 268 ? 67.124 105.322 -0.863 1.00 26.00 ? 268 ASN A OD1 1 ATOM 2095 N ND2 . ASN A 1 268 ? 67.367 107.438 -0.100 1.00 24.46 ? 268 ASN A ND2 1 ATOM 2096 N N . THR A 1 269 ? 66.869 103.549 4.062 1.00 17.34 ? 269 THR A N 1 ATOM 2097 C CA . THR A 1 269 ? 67.280 103.026 5.367 1.00 16.92 ? 269 THR A CA 1 ATOM 2098 C C . THR A 1 269 ? 66.042 102.422 6.086 1.00 15.51 ? 269 THR A C 1 ATOM 2099 O O . THR A 1 269 ? 64.943 102.755 5.741 1.00 16.10 ? 269 THR A O 1 ATOM 2100 C CB . THR A 1 269 ? 67.845 104.150 6.247 1.00 15.80 ? 269 THR A CB 1 ATOM 2101 O OG1 . THR A 1 269 ? 66.808 105.111 6.510 1.00 18.89 ? 269 THR A OG1 1 ATOM 2102 C CG2 . THR A 1 269 ? 69.092 104.874 5.580 1.00 16.65 ? 269 THR A CG2 1 ATOM 2103 N N . PRO A 1 270 ? 66.227 101.528 7.072 1.00 15.26 ? 270 PRO A N 1 ATOM 2104 C CA . PRO A 1 270 ? 65.059 101.110 7.879 1.00 14.75 ? 270 PRO A CA 1 ATOM 2105 C C . PRO A 1 270 ? 64.237 102.244 8.489 1.00 16.23 ? 270 PRO A C 1 ATOM 2106 O O . PRO A 1 270 ? 62.998 102.166 8.501 1.00 15.69 ? 270 PRO A O 1 ATOM 2107 C CB . PRO A 1 270 ? 65.694 100.249 8.974 1.00 14.22 ? 270 PRO A CB 1 ATOM 2108 C CG . PRO A 1 270 ? 66.878 99.611 8.305 1.00 12.40 ? 270 PRO A CG 1 ATOM 2109 C CD . PRO A 1 270 ? 67.446 100.785 7.466 1.00 14.21 ? 270 PRO A CD 1 ATOM 2110 N N . GLU A 1 271 ? 64.905 103.281 9.007 1.00 16.15 ? 271 GLU A N 1 ATOM 2111 C CA . GLU A 1 271 ? 64.202 104.420 9.598 1.00 17.35 ? 271 GLU A CA 1 ATOM 2112 C C . GLU A 1 271 ? 63.282 105.120 8.612 1.00 17.68 ? 271 GLU A C 1 ATOM 2113 O O . GLU A 1 271 ? 62.185 105.550 8.986 1.00 16.78 ? 271 GLU A O 1 ATOM 2114 C CB . GLU A 1 271 ? 65.184 105.420 10.197 1.00 17.30 ? 271 GLU A CB 1 ATOM 2115 C CG . GLU A 1 271 ? 65.753 104.963 11.519 1.00 20.33 ? 271 GLU A CG 1 ATOM 2116 C CD . GLU A 1 271 ? 64.698 105.025 12.624 1.00 21.51 ? 271 GLU A CD 1 ATOM 2117 O OE1 . GLU A 1 271 ? 64.191 106.129 12.913 1.00 23.35 ? 271 GLU A OE1 1 ATOM 2118 O OE2 . GLU A 1 271 ? 64.369 103.959 13.186 1.00 23.01 ? 271 GLU A OE2 1 ATOM 2119 N N . GLN A 1 272 ? 63.726 105.255 7.361 1.00 18.46 ? 272 GLN A N 1 ATOM 2120 C CA . GLN A 1 272 ? 62.893 105.901 6.335 1.00 20.57 ? 272 GLN A CA 1 ATOM 2121 C C . GLN A 1 272 ? 61.660 105.061 5.992 1.00 19.60 ? 272 GLN A C 1 ATOM 2122 O O . GLN A 1 272 ? 60.609 105.619 5.704 1.00 19.87 ? 272 GLN A O 1 ATOM 2123 C CB . GLN A 1 272 ? 63.682 106.210 5.055 1.00 20.46 ? 272 GLN A CB 1 ATOM 2124 C CG . GLN A 1 272 ? 64.791 107.233 5.223 1.00 22.96 ? 272 GLN A CG 1 ATOM 2125 C CD . GLN A 1 272 ? 65.467 107.574 3.891 1.00 25.68 ? 272 GLN A CD 1 ATOM 2126 O OE1 . GLN A 1 272 ? 65.205 106.943 2.842 1.00 31.19 ? 272 GLN A OE1 1 ATOM 2127 N NE2 . GLN A 1 272 ? 66.308 108.594 3.915 1.00 31.80 ? 272 GLN A NE2 1 ATOM 2128 N N . VAL A 1 273 ? 61.771 103.735 6.058 1.00 18.47 ? 273 VAL A N 1 ATOM 2129 C CA . VAL A 1 273 ? 60.565 102.864 5.883 1.00 17.35 ? 273 VAL A CA 1 ATOM 2130 C C . VAL A 1 273 ? 59.507 103.109 6.985 1.00 17.33 ? 273 VAL A C 1 ATOM 2131 O O . VAL A 1 273 ? 58.333 103.260 6.676 1.00 16.52 ? 273 VAL A O 1 ATOM 2132 C CB . VAL A 1 273 ? 60.916 101.388 5.752 1.00 17.30 ? 273 VAL A CB 1 ATOM 2133 C CG1 . VAL A 1 273 ? 59.638 100.483 5.822 1.00 14.05 ? 273 VAL A CG1 1 ATOM 2134 C CG2 . VAL A 1 273 ? 61.680 101.182 4.463 1.00 15.04 ? 273 VAL A CG2 1 ATOM 2135 N N . VAL A 1 274 ? 59.960 103.247 8.233 1.00 17.54 ? 274 VAL A N 1 ATOM 2136 C CA . VAL A 1 274 ? 59.073 103.519 9.368 1.00 17.42 ? 274 VAL A CA 1 ATOM 2137 C C . VAL A 1 274 ? 58.449 104.895 9.175 1.00 17.79 ? 274 VAL A C 1 ATOM 2138 O O . VAL A 1 274 ? 57.248 105.091 9.357 1.00 18.37 ? 274 VAL A O 1 ATOM 2139 C CB . VAL A 1 274 ? 59.822 103.386 10.738 1.00 16.80 ? 274 VAL A CB 1 ATOM 2140 C CG1 . VAL A 1 274 ? 58.931 103.752 11.915 1.00 15.76 ? 274 VAL A CG1 1 ATOM 2141 C CG2 . VAL A 1 274 ? 60.423 101.972 10.923 1.00 15.74 ? 274 VAL A CG2 1 ATOM 2142 N N . GLN A 1 275 ? 59.264 105.862 8.783 1.00 17.75 ? 275 GLN A N 1 ATOM 2143 C CA . GLN A 1 275 ? 58.742 107.182 8.489 1.00 18.23 ? 275 GLN A CA 1 ATOM 2144 C C . GLN A 1 275 ? 57.653 107.175 7.391 1.00 17.24 ? 275 GLN A C 1 ATOM 2145 O O . GLN A 1 275 ? 56.632 107.850 7.522 1.00 17.86 ? 275 GLN A O 1 ATOM 2146 C CB . GLN A 1 275 ? 59.873 108.139 8.134 1.00 17.43 ? 275 GLN A CB 1 ATOM 2147 C CG . GLN A 1 275 ? 60.858 108.410 9.286 1.00 18.29 ? 275 GLN A CG 1 ATOM 2148 C CD . GLN A 1 275 ? 62.138 109.104 8.786 1.00 21.00 ? 275 GLN A CD 1 ATOM 2149 O OE1 . GLN A 1 275 ? 62.322 109.262 7.565 1.00 22.32 ? 275 GLN A OE1 1 ATOM 2150 N NE2 . GLN A 1 275 ? 63.020 109.529 9.727 1.00 21.82 ? 275 GLN A NE2 1 ATOM 2151 N N . GLU A 1 276 ? 57.877 106.454 6.306 1.00 16.51 ? 276 GLU A N 1 ATOM 2152 C CA . GLU A 1 276 ? 56.851 106.325 5.243 1.00 16.71 ? 276 GLU A CA 1 ATOM 2153 C C . GLU A 1 276 ? 55.574 105.652 5.744 1.00 15.88 ? 276 GLU A C 1 ATOM 2154 O O . GLU A 1 276 ? 54.483 106.106 5.433 1.00 15.77 ? 276 GLU A O 1 ATOM 2155 C CB . GLU A 1 276 ? 57.393 105.486 4.085 1.00 16.75 ? 276 GLU A CB 1 ATOM 2156 C CG . GLU A 1 276 ? 58.494 106.164 3.301 1.00 19.22 ? 276 GLU A CG 1 ATOM 2157 C CD . GLU A 1 276 ? 58.053 107.433 2.600 1.00 25.88 ? 276 GLU A CD 1 ATOM 2158 O OE1 . GLU A 1 276 ? 56.810 107.675 2.404 1.00 28.33 ? 276 GLU A OE1 1 ATOM 2159 O OE2 . GLU A 1 276 ? 58.977 108.196 2.233 1.00 28.79 ? 276 GLU A OE2 1 ATOM 2160 N N . TYR A 1 277 ? 55.716 104.573 6.515 1.00 15.43 ? 277 TYR A N 1 ATOM 2161 C CA . TYR A 1 277 ? 54.560 103.895 7.152 1.00 15.63 ? 277 TYR A CA 1 ATOM 2162 C C . TYR A 1 277 ? 53.760 104.816 8.047 1.00 16.80 ? 277 TYR A C 1 ATOM 2163 O O . TYR A 1 277 ? 52.526 104.920 7.903 1.00 17.53 ? 277 TYR A O 1 ATOM 2164 C CB . TYR A 1 277 ? 55.007 102.645 7.952 1.00 16.29 ? 277 TYR A CB 1 ATOM 2165 C CG . TYR A 1 277 ? 53.860 101.991 8.735 1.00 16.82 ? 277 TYR A CG 1 ATOM 2166 C CD1 . TYR A 1 277 ? 52.667 101.595 8.096 1.00 17.47 ? 277 TYR A CD1 1 ATOM 2167 C CD2 . TYR A 1 277 ? 53.958 101.805 10.108 1.00 18.04 ? 277 TYR A CD2 1 ATOM 2168 C CE1 . TYR A 1 277 ? 51.612 100.981 8.829 1.00 17.39 ? 277 TYR A CE1 1 ATOM 2169 C CE2 . TYR A 1 277 ? 52.921 101.194 10.841 1.00 18.25 ? 277 TYR A CE2 1 ATOM 2170 C CZ . TYR A 1 277 ? 51.764 100.796 10.198 1.00 18.01 ? 277 TYR A CZ 1 ATOM 2171 O OH . TYR A 1 277 ? 50.767 100.241 10.958 1.00 18.22 ? 277 TYR A OH 1 ATOM 2172 N N . LEU A 1 278 ? 54.447 105.542 8.938 1.00 17.41 ? 278 LEU A N 1 ATOM 2173 C CA . LEU A 1 278 ? 53.765 106.478 9.851 1.00 17.53 ? 278 LEU A CA 1 ATOM 2174 C C . LEU A 1 278 ? 53.171 107.711 9.171 1.00 17.68 ? 278 LEU A C 1 ATOM 2175 O O . LEU A 1 278 ? 52.189 108.323 9.666 1.00 17.58 ? 278 LEU A O 1 ATOM 2176 C CB . LEU A 1 278 ? 54.692 106.859 11.018 1.00 16.70 ? 278 LEU A CB 1 ATOM 2177 C CG . LEU A 1 278 ? 55.224 105.649 11.814 1.00 16.77 ? 278 LEU A CG 1 ATOM 2178 C CD1 . LEU A 1 278 ? 56.043 106.050 13.026 1.00 12.84 ? 278 LEU A CD1 1 ATOM 2179 C CD2 . LEU A 1 278 ? 54.121 104.659 12.229 1.00 15.47 ? 278 LEU A CD2 1 ATOM 2180 N N . GLU A 1 279 ? 53.738 108.073 8.029 1.00 19.10 ? 279 GLU A N 1 ATOM 2181 C CA . GLU A 1 279 ? 53.198 109.157 7.204 1.00 19.52 ? 279 GLU A CA 1 ATOM 2182 C C . GLU A 1 279 ? 51.845 108.730 6.685 1.00 20.16 ? 279 GLU A C 1 ATOM 2183 O O . GLU A 1 279 ? 50.897 109.536 6.594 1.00 22.41 ? 279 GLU A O 1 ATOM 2184 C CB . GLU A 1 279 ? 54.176 109.493 6.064 1.00 19.39 ? 279 GLU A CB 1 ATOM 2185 C CG . GLU A 1 279 ? 53.645 110.389 4.920 1.00 23.40 ? 279 GLU A CG 1 ATOM 2186 C CD . GLU A 1 279 ? 53.140 111.759 5.372 1.00 30.72 ? 279 GLU A CD 1 ATOM 2187 O OE1 . GLU A 1 279 ? 53.798 112.374 6.258 1.00 32.47 ? 279 GLU A OE1 1 ATOM 2188 O OE2 . GLU A 1 279 ? 52.086 112.223 4.824 1.00 32.14 ? 279 GLU A OE2 1 ATOM 2189 N N . LEU A 1 280 ? 51.712 107.455 6.357 1.00 20.05 ? 280 LEU A N 1 ATOM 2190 C CA . LEU A 1 280 ? 50.377 106.933 6.011 1.00 19.04 ? 280 LEU A CA 1 ATOM 2191 C C . LEU A 1 280 ? 49.412 106.782 7.196 1.00 18.41 ? 280 LEU A C 1 ATOM 2192 O O . LEU A 1 280 ? 48.362 107.424 7.219 1.00 17.43 ? 280 LEU A O 1 ATOM 2193 C CB . LEU A 1 280 ? 50.485 105.616 5.217 1.00 19.02 ? 280 LEU A CB 1 ATOM 2194 C CG . LEU A 1 280 ? 49.077 105.060 4.918 1.00 18.99 ? 280 LEU A CG 1 ATOM 2195 C CD1 . LEU A 1 280 ? 48.494 105.770 3.714 1.00 12.51 ? 280 LEU A CD1 1 ATOM 2196 C CD2 . LEU A 1 280 ? 49.098 103.556 4.766 1.00 20.31 ? 280 LEU A CD2 1 ATOM 2197 N N . ILE A 1 281 ? 49.732 105.952 8.192 1.00 18.47 ? 281 ILE A N 1 ATOM 2198 C CA . ILE A 1 281 ? 48.680 105.595 9.165 1.00 19.68 ? 281 ILE A CA 1 ATOM 2199 C C . ILE A 1 281 ? 48.560 106.600 10.307 1.00 19.84 ? 281 ILE A C 1 ATOM 2200 O O . ILE A 1 281 ? 47.600 106.499 11.096 1.00 18.78 ? 281 ILE A O 1 ATOM 2201 C CB . ILE A 1 281 ? 48.797 104.154 9.844 1.00 19.75 ? 281 ILE A CB 1 ATOM 2202 C CG1 . ILE A 1 281 ? 50.243 103.806 10.025 1.00 21.14 ? 281 ILE A CG1 1 ATOM 2203 C CG2 . ILE A 1 281 ? 47.788 103.042 9.269 1.00 20.85 ? 281 ILE A CG2 1 ATOM 2204 C CD1 . ILE A 1 281 ? 50.673 104.299 11.303 1.00 20.68 ? 281 ILE A CD1 1 ATOM 2205 N N . GLY A 1 282 ? 49.542 107.513 10.428 1.00 19.02 ? 282 GLY A N 1 ATOM 2206 C CA . GLY A 1 282 ? 49.525 108.481 11.520 1.00 19.26 ? 282 GLY A CA 1 ATOM 2207 C C . GLY A 1 282 ? 50.700 108.372 12.483 1.00 20.20 ? 282 GLY A C 1 ATOM 2208 O O . GLY A 1 282 ? 50.972 107.301 13.050 1.00 19.69 ? 282 GLY A O 1 ATOM 2209 N N . ARG A 1 283 ? 51.401 109.502 12.664 1.00 19.55 ? 283 ARG A N 1 ATOM 2210 C CA . ARG A 1 283 ? 52.552 109.578 13.540 1.00 19.08 ? 283 ARG A CA 1 ATOM 2211 C C . ARG A 1 283 ? 52.100 109.617 14.972 1.00 18.66 ? 283 ARG A C 1 ATOM 2212 O O . ARG A 1 283 ? 50.995 110.061 15.253 1.00 17.23 ? 283 ARG A O 1 ATOM 2213 C CB . ARG A 1 283 ? 53.406 110.834 13.227 1.00 19.48 ? 283 ARG A CB 1 ATOM 2214 C CG . ARG A 1 283 ? 54.299 110.630 12.036 1.00 18.92 ? 283 ARG A CG 1 ATOM 2215 C CD . ARG A 1 283 ? 55.146 111.866 11.724 1.00 20.16 ? 283 ARG A CD 1 ATOM 2216 N NE . ARG A 1 283 ? 54.296 112.886 11.135 1.00 22.62 ? 283 ARG A NE 1 ATOM 2217 C CZ . ARG A 1 283 ? 54.072 113.025 9.833 1.00 27.30 ? 283 ARG A CZ 1 ATOM 2218 N NH1 . ARG A 1 283 ? 54.672 112.233 8.934 1.00 25.92 ? 283 ARG A NH1 1 ATOM 2219 N NH2 . ARG A 1 283 ? 53.259 113.986 9.424 1.00 29.21 ? 283 ARG A NH2 1 ATOM 2220 N N . PRO A 1 284 ? 52.951 109.128 15.894 1.00 18.52 ? 284 PRO A N 1 ATOM 2221 C CA . PRO A 1 284 ? 52.526 109.075 17.290 1.00 18.91 ? 284 PRO A CA 1 ATOM 2222 C C . PRO A 1 284 ? 52.326 110.428 17.931 1.00 19.14 ? 284 PRO A C 1 ATOM 2223 O O . PRO A 1 284 ? 52.987 111.402 17.561 1.00 20.09 ? 284 PRO A O 1 ATOM 2224 C CB . PRO A 1 284 ? 53.693 108.333 17.988 1.00 19.05 ? 284 PRO A CB 1 ATOM 2225 C CG . PRO A 1 284 ? 54.832 108.558 17.128 1.00 18.33 ? 284 PRO A CG 1 ATOM 2226 C CD . PRO A 1 284 ? 54.285 108.537 15.715 1.00 18.09 ? 284 PRO A CD 1 ATOM 2227 N N . ALA A 1 285 ? 51.464 110.471 18.935 1.00 19.34 ? 285 ALA A N 1 ATOM 2228 C CA . ALA A 1 285 ? 51.211 111.702 19.678 1.00 20.07 ? 285 ALA A CA 1 ATOM 2229 C C . ALA A 1 285 ? 52.484 112.047 20.456 1.00 20.39 ? 285 ALA A C 1 ATOM 2230 O O . ALA A 1 285 ? 53.275 111.157 20.789 1.00 20.55 ? 285 ALA A O 1 ATOM 2231 C CB . ALA A 1 285 ? 50.021 111.514 20.657 1.00 20.13 ? 285 ALA A CB 1 ATOM 2232 N N . LEU A 1 286 ? 52.685 113.319 20.762 1.00 20.46 ? 286 LEU A N 1 ATOM 2233 C CA . LEU A 1 286 ? 53.807 113.700 21.630 1.00 20.47 ? 286 LEU A CA 1 ATOM 2234 C C . LEU A 1 286 ? 53.390 113.460 23.066 1.00 19.82 ? 286 LEU A C 1 ATOM 2235 O O . LEU A 1 286 ? 52.354 113.968 23.484 1.00 20.83 ? 286 LEU A O 1 ATOM 2236 C CB . LEU A 1 286 ? 54.173 115.184 21.412 1.00 21.26 ? 286 LEU A CB 1 ATOM 2237 C CG . LEU A 1 286 ? 55.493 115.641 22.065 1.00 22.39 ? 286 LEU A CG 1 ATOM 2238 C CD1 . LEU A 1 286 ? 56.699 114.798 21.643 1.00 23.39 ? 286 LEU A CD1 1 ATOM 2239 C CD2 . LEU A 1 286 ? 55.712 117.090 21.743 1.00 24.90 ? 286 LEU A CD2 1 ATOM 2240 N N . PRO A 1 287 ? 54.164 112.671 23.834 1.00 19.97 ? 287 PRO A N 1 ATOM 2241 C CA . PRO A 1 287 ? 53.739 112.439 25.230 1.00 19.88 ? 287 PRO A CA 1 ATOM 2242 C C . PRO A 1 287 ? 53.863 113.690 26.099 1.00 19.20 ? 287 PRO A C 1 ATOM 2243 O O . PRO A 1 287 ? 54.594 114.601 25.746 1.00 18.84 ? 287 PRO A O 1 ATOM 2244 C CB . PRO A 1 287 ? 54.721 111.368 25.741 1.00 19.96 ? 287 PRO A CB 1 ATOM 2245 C CG . PRO A 1 287 ? 55.413 110.859 24.525 1.00 20.57 ? 287 PRO A CG 1 ATOM 2246 C CD . PRO A 1 287 ? 55.430 111.967 23.540 1.00 18.99 ? 287 PRO A CD 1 ATOM 2247 N N . SER A 1 288 ? 53.114 113.741 27.202 1.00 18.65 ? 288 SER A N 1 ATOM 2248 C CA . SER A 1 288 ? 53.320 114.776 28.191 1.00 18.38 ? 288 SER A CA 1 ATOM 2249 C C . SER A 1 288 ? 54.699 114.463 28.749 1.00 18.40 ? 288 SER A C 1 ATOM 2250 O O . SER A 1 288 ? 55.062 113.301 28.856 1.00 18.28 ? 288 SER A O 1 ATOM 2251 C CB . SER A 1 288 ? 52.285 114.696 29.325 1.00 18.20 ? 288 SER A CB 1 ATOM 2252 O OG . SER A 1 288 ? 50.979 115.030 28.869 1.00 17.79 ? 288 SER A OG 1 ATOM 2253 N N . TYR A 1 289 ? 55.473 115.487 29.089 1.00 17.90 ? 289 TYR A N 1 ATOM 2254 C CA . TYR A 1 289 ? 56.815 115.245 29.588 1.00 19.25 ? 289 TYR A CA 1 ATOM 2255 C C . TYR A 1 289 ? 56.799 114.377 30.863 1.00 18.29 ? 289 TYR A C 1 ATOM 2256 O O . TYR A 1 289 ? 57.648 113.489 31.054 1.00 17.94 ? 289 TYR A O 1 ATOM 2257 C CB . TYR A 1 289 ? 57.491 116.590 29.818 1.00 19.37 ? 289 TYR A CB 1 ATOM 2258 C CG . TYR A 1 289 ? 59.003 116.552 30.034 1.00 20.84 ? 289 TYR A CG 1 ATOM 2259 C CD1 . TYR A 1 289 ? 59.869 116.808 28.976 1.00 19.06 ? 289 TYR A CD1 1 ATOM 2260 C CD2 . TYR A 1 289 ? 59.556 116.340 31.313 1.00 22.48 ? 289 TYR A CD2 1 ATOM 2261 C CE1 . TYR A 1 289 ? 61.237 116.856 29.156 1.00 18.58 ? 289 TYR A CE1 1 ATOM 2262 C CE2 . TYR A 1 289 ? 60.947 116.343 31.509 1.00 18.81 ? 289 TYR A CE2 1 ATOM 2263 C CZ . TYR A 1 289 ? 61.768 116.612 30.419 1.00 19.44 ? 289 TYR A CZ 1 ATOM 2264 O OH . TYR A 1 289 ? 63.123 116.655 30.574 1.00 19.98 ? 289 TYR A OH 1 ATOM 2265 N N . TRP A 1 290 ? 55.816 114.603 31.726 1.00 17.95 ? 290 TRP A N 1 ATOM 2266 C CA . TRP A 1 290 ? 55.690 113.795 32.953 1.00 18.59 ? 290 TRP A CA 1 ATOM 2267 C C . TRP A 1 290 ? 55.440 112.302 32.697 1.00 18.32 ? 290 TRP A C 1 ATOM 2268 O O . TRP A 1 290 ? 55.858 111.461 33.513 1.00 18.31 ? 290 TRP A O 1 ATOM 2269 C CB . TRP A 1 290 ? 54.647 114.376 33.912 1.00 18.44 ? 290 TRP A CB 1 ATOM 2270 C CG . TRP A 1 290 ? 53.222 114.438 33.370 1.00 18.71 ? 290 TRP A CG 1 ATOM 2271 C CD1 . TRP A 1 290 ? 52.577 115.533 32.853 1.00 19.11 ? 290 TRP A CD1 1 ATOM 2272 C CD2 . TRP A 1 290 ? 52.272 113.377 33.369 1.00 18.44 ? 290 TRP A CD2 1 ATOM 2273 N NE1 . TRP A 1 290 ? 51.291 115.206 32.508 1.00 16.99 ? 290 TRP A NE1 1 ATOM 2274 C CE2 . TRP A 1 290 ? 51.075 113.889 32.823 1.00 19.42 ? 290 TRP A CE2 1 ATOM 2275 C CE3 . TRP A 1 290 ? 52.313 112.025 33.774 1.00 16.35 ? 290 TRP A CE3 1 ATOM 2276 C CZ2 . TRP A 1 290 ? 49.938 113.111 32.681 1.00 15.77 ? 290 TRP A CZ2 1 ATOM 2277 C CZ3 . TRP A 1 290 ? 51.182 111.257 33.610 1.00 18.31 ? 290 TRP A CZ3 1 ATOM 2278 C CH2 . TRP A 1 290 ? 50.013 111.805 33.069 1.00 18.39 ? 290 TRP A CH2 1 ATOM 2279 N N . ALA A 1 291 ? 54.832 111.967 31.546 1.00 17.11 ? 291 ALA A N 1 ATOM 2280 C CA . ALA A 1 291 ? 54.564 110.545 31.220 1.00 17.48 ? 291 ALA A CA 1 ATOM 2281 C C . ALA A 1 291 ? 55.853 109.789 30.906 1.00 17.91 ? 291 ALA A C 1 ATOM 2282 O O . ALA A 1 291 ? 55.839 108.554 30.887 1.00 16.56 ? 291 ALA A O 1 ATOM 2283 C CB . ALA A 1 291 ? 53.583 110.404 30.066 1.00 15.74 ? 291 ALA A CB 1 ATOM 2284 N N . LEU A 1 292 ? 56.958 110.528 30.691 1.00 18.42 ? 292 LEU A N 1 ATOM 2285 C CA . LEU A 1 292 ? 58.299 109.926 30.516 1.00 19.03 ? 292 LEU A CA 1 ATOM 2286 C C . LEU A 1 292 ? 58.996 109.548 31.840 1.00 19.27 ? 292 LEU A C 1 ATOM 2287 O O . LEU A 1 292 ? 60.009 108.816 31.841 1.00 19.09 ? 292 LEU A O 1 ATOM 2288 C CB . LEU A 1 292 ? 59.236 110.839 29.713 1.00 19.70 ? 292 LEU A CB 1 ATOM 2289 C CG . LEU A 1 292 ? 58.891 111.466 28.350 1.00 22.35 ? 292 LEU A CG 1 ATOM 2290 C CD1 . LEU A 1 292 ? 60.161 111.870 27.596 1.00 24.15 ? 292 LEU A CD1 1 ATOM 2291 C CD2 . LEU A 1 292 ? 58.164 110.562 27.496 1.00 25.11 ? 292 LEU A CD2 1 ATOM 2292 N N . GLY A 1 293 ? 58.449 109.991 32.972 1.00 19.38 ? 293 GLY A N 1 ATOM 2293 C CA . GLY A 1 293 ? 59.010 109.559 34.242 1.00 18.91 ? 293 GLY A CA 1 ATOM 2294 C C . GLY A 1 293 ? 58.568 108.165 34.597 1.00 19.36 ? 293 GLY A C 1 ATOM 2295 O O . GLY A 1 293 ? 57.897 107.481 33.790 1.00 20.98 ? 293 GLY A O 1 ATOM 2296 N N . PHE A 1 294 ? 58.936 107.730 35.800 1.00 18.32 ? 294 PHE A N 1 ATOM 2297 C CA . PHE A 1 294 ? 58.618 106.411 36.305 1.00 17.50 ? 294 PHE A CA 1 ATOM 2298 C C . PHE A 1 294 ? 57.182 106.363 36.834 1.00 17.80 ? 294 PHE A C 1 ATOM 2299 O O . PHE A 1 294 ? 56.748 107.270 37.552 1.00 16.53 ? 294 PHE A O 1 ATOM 2300 C CB . PHE A 1 294 ? 59.580 106.097 37.423 1.00 17.64 ? 294 PHE A CB 1 ATOM 2301 C CG . PHE A 1 294 ? 59.451 104.709 37.997 1.00 17.90 ? 294 PHE A CG 1 ATOM 2302 C CD1 . PHE A 1 294 ? 59.692 103.579 37.214 1.00 15.97 ? 294 PHE A CD1 1 ATOM 2303 C CD2 . PHE A 1 294 ? 59.129 104.550 39.343 1.00 18.91 ? 294 PHE A CD2 1 ATOM 2304 C CE1 . PHE A 1 294 ? 59.583 102.311 37.751 1.00 16.42 ? 294 PHE A CE1 1 ATOM 2305 C CE2 . PHE A 1 294 ? 59.031 103.297 39.915 1.00 18.61 ? 294 PHE A CE2 1 ATOM 2306 C CZ . PHE A 1 294 ? 59.267 102.163 39.116 1.00 17.90 ? 294 PHE A CZ 1 ATOM 2307 N N . HIS A 1 295 ? 56.475 105.292 36.473 1.00 17.25 ? 295 HIS A N 1 ATOM 2308 C CA . HIS A 1 295 ? 55.091 105.041 36.873 1.00 17.13 ? 295 HIS A CA 1 ATOM 2309 C C . HIS A 1 295 ? 55.118 103.857 37.834 1.00 18.47 ? 295 HIS A C 1 ATOM 2310 O O . HIS A 1 295 ? 55.832 102.881 37.597 1.00 18.48 ? 295 HIS A O 1 ATOM 2311 C CB . HIS A 1 295 ? 54.250 104.610 35.668 1.00 16.69 ? 295 HIS A CB 1 ATOM 2312 C CG . HIS A 1 295 ? 54.094 105.640 34.592 1.00 14.76 ? 295 HIS A CG 1 ATOM 2313 N ND1 . HIS A 1 295 ? 55.153 106.109 33.837 1.00 18.46 ? 295 HIS A ND1 1 ATOM 2314 C CD2 . HIS A 1 295 ? 52.989 106.250 34.101 1.00 12.34 ? 295 HIS A CD2 1 ATOM 2315 C CE1 . HIS A 1 295 ? 54.708 106.981 32.944 1.00 15.29 ? 295 HIS A CE1 1 ATOM 2316 N NE2 . HIS A 1 295 ? 53.397 107.067 33.065 1.00 14.07 ? 295 HIS A NE2 1 ATOM 2317 N N . LEU A 1 296 ? 54.362 103.931 38.918 1.00 18.72 ? 296 LEU A N 1 ATOM 2318 C CA . LEU A 1 296 ? 54.252 102.810 39.844 1.00 19.46 ? 296 LEU A CA 1 ATOM 2319 C C . LEU A 1 296 ? 52.781 102.406 39.959 1.00 19.46 ? 296 LEU A C 1 ATOM 2320 O O . LEU A 1 296 ? 51.920 103.244 39.868 1.00 19.01 ? 296 LEU A O 1 ATOM 2321 C CB . LEU A 1 296 ? 54.819 103.203 41.218 1.00 19.93 ? 296 LEU A CB 1 ATOM 2322 C CG . LEU A 1 296 ? 54.975 102.117 42.285 1.00 21.42 ? 296 LEU A CG 1 ATOM 2323 C CD1 . LEU A 1 296 ? 55.861 101.003 41.780 1.00 18.78 ? 296 LEU A CD1 1 ATOM 2324 C CD2 . LEU A 1 296 ? 55.543 102.763 43.573 1.00 20.19 ? 296 LEU A CD2 1 ATOM 2325 N N . SER A 1 297 ? 52.512 101.116 40.174 1.00 20.33 ? 297 SER A N 1 ATOM 2326 C CA . SER A 1 297 ? 51.178 100.561 40.045 1.00 20.75 ? 297 SER A CA 1 ATOM 2327 C C . SER A 1 297 ? 51.075 99.152 40.643 1.00 20.65 ? 297 SER A C 1 ATOM 2328 O O . SER A 1 297 ? 52.070 98.423 40.744 1.00 20.23 ? 297 SER A O 1 ATOM 2329 C CB . SER A 1 297 ? 50.808 100.512 38.543 1.00 21.13 ? 297 SER A CB 1 ATOM 2330 O OG . SER A 1 297 ? 49.508 99.957 38.350 1.00 23.70 ? 297 SER A OG 1 ATOM 2331 N N . ARG A 1 298 ? 49.874 98.763 41.054 1.00 21.06 ? 298 ARG A N 1 ATOM 2332 C CA . ARG A 1 298 ? 49.602 97.342 41.249 1.00 22.30 ? 298 ARG A CA 1 ATOM 2333 C C . ARG A 1 298 ? 48.141 97.095 41.229 1.00 22.80 ? 298 ARG A C 1 ATOM 2334 O O . ARG A 1 298 ? 47.368 97.978 41.523 1.00 23.41 ? 298 ARG A O 1 ATOM 2335 C CB . ARG A 1 298 ? 50.221 96.726 42.523 1.00 22.09 ? 298 ARG A CB 1 ATOM 2336 C CG . ARG A 1 298 ? 49.391 96.877 43.794 1.00 23.04 ? 298 ARG A CG 1 ATOM 2337 C CD . ARG A 1 298 ? 49.859 95.958 44.891 1.00 23.29 ? 298 ARG A CD 1 ATOM 2338 N NE . ARG A 1 298 ? 49.607 94.541 44.581 1.00 24.01 ? 298 ARG A NE 1 ATOM 2339 C CZ . ARG A 1 298 ? 50.276 93.530 45.136 1.00 23.68 ? 298 ARG A CZ 1 ATOM 2340 N NH1 . ARG A 1 298 ? 51.240 93.776 46.027 1.00 20.38 ? 298 ARG A NH1 1 ATOM 2341 N NH2 . ARG A 1 298 ? 50.004 92.275 44.787 1.00 20.82 ? 298 ARG A NH2 1 ATOM 2342 N N . TYR A 1 299 ? 47.792 95.870 40.857 1.00 23.17 ? 299 TYR A N 1 ATOM 2343 C CA . TYR A 1 299 ? 46.453 95.344 41.006 1.00 23.69 ? 299 TYR A CA 1 ATOM 2344 C C . TYR A 1 299 ? 46.254 94.961 42.476 1.00 23.81 ? 299 TYR A C 1 ATOM 2345 O O . TYR A 1 299 ? 46.943 94.100 43.008 1.00 24.18 ? 299 TYR A O 1 ATOM 2346 C CB . TYR A 1 299 ? 46.276 94.147 40.045 1.00 23.08 ? 299 TYR A CB 1 ATOM 2347 C CG . TYR A 1 299 ? 44.888 93.497 39.971 1.00 23.02 ? 299 TYR A CG 1 ATOM 2348 C CD1 . TYR A 1 299 ? 44.719 92.300 39.251 1.00 24.27 ? 299 TYR A CD1 1 ATOM 2349 C CD2 . TYR A 1 299 ? 43.779 94.034 40.615 1.00 20.54 ? 299 TYR A CD2 1 ATOM 2350 C CE1 . TYR A 1 299 ? 43.484 91.661 39.154 1.00 22.10 ? 299 TYR A CE1 1 ATOM 2351 C CE2 . TYR A 1 299 ? 42.544 93.403 40.539 1.00 20.48 ? 299 TYR A CE2 1 ATOM 2352 C CZ . TYR A 1 299 ? 42.413 92.214 39.802 1.00 22.37 ? 299 TYR A CZ 1 ATOM 2353 O OH . TYR A 1 299 ? 41.213 91.561 39.685 1.00 24.62 ? 299 TYR A OH 1 ATOM 2354 N N . GLU A 1 300 ? 45.325 95.647 43.136 1.00 24.77 ? 300 GLU A N 1 ATOM 2355 C CA . GLU A 1 300 ? 44.951 95.334 44.517 1.00 25.36 ? 300 GLU A CA 1 ATOM 2356 C C . GLU A 1 300 ? 45.928 95.809 45.564 1.00 24.25 ? 300 GLU A C 1 ATOM 2357 O O . GLU A 1 300 ? 46.519 95.027 46.281 1.00 23.58 ? 300 GLU A O 1 ATOM 2358 C CB . GLU A 1 300 ? 44.608 93.835 44.747 1.00 26.02 ? 300 GLU A CB 1 ATOM 2359 C CG . GLU A 1 300 ? 43.282 93.393 44.108 1.00 28.44 ? 300 GLU A CG 1 ATOM 2360 C CD . GLU A 1 300 ? 42.016 93.920 44.797 1.00 33.78 ? 300 GLU A CD 1 ATOM 2361 O OE1 . GLU A 1 300 ? 42.071 94.288 46.005 1.00 33.33 ? 300 GLU A OE1 1 ATOM 2362 O OE2 . GLU A 1 300 ? 40.949 93.943 44.107 1.00 36.70 ? 300 GLU A OE2 1 ATOM 2363 N N . TYR A 1 301 ? 46.041 97.121 45.671 1.00 25.11 ? 301 TYR A N 1 ATOM 2364 C CA . TYR A 1 301 ? 46.500 97.735 46.912 1.00 25.09 ? 301 TYR A CA 1 ATOM 2365 C C . TYR A 1 301 ? 45.502 97.343 47.971 1.00 25.94 ? 301 TYR A C 1 ATOM 2366 O O . TYR A 1 301 ? 45.875 97.037 49.096 1.00 26.31 ? 301 TYR A O 1 ATOM 2367 C CB . TYR A 1 301 ? 46.638 99.250 46.751 1.00 24.86 ? 301 TYR A CB 1 ATOM 2368 C CG . TYR A 1 301 ? 47.854 99.635 45.906 1.00 24.05 ? 301 TYR A CG 1 ATOM 2369 C CD1 . TYR A 1 301 ? 49.149 99.390 46.369 1.00 24.03 ? 301 TYR A CD1 1 ATOM 2370 C CD2 . TYR A 1 301 ? 47.700 100.259 44.654 1.00 22.77 ? 301 TYR A CD2 1 ATOM 2371 C CE1 . TYR A 1 301 ? 50.274 99.766 45.594 1.00 25.05 ? 301 TYR A CE1 1 ATOM 2372 C CE2 . TYR A 1 301 ? 48.808 100.616 43.871 1.00 23.63 ? 301 TYR A CE2 1 ATOM 2373 C CZ . TYR A 1 301 ? 50.082 100.374 44.342 1.00 23.77 ? 301 TYR A CZ 1 ATOM 2374 O OH . TYR A 1 301 ? 51.186 100.710 43.561 1.00 25.60 ? 301 TYR A OH 1 ATOM 2375 N N . GLY A 1 302 ? 44.227 97.280 47.581 1.00 26.29 ? 302 GLY A N 1 ATOM 2376 C CA . GLY A 1 302 ? 43.162 96.797 48.461 1.00 26.43 ? 302 GLY A CA 1 ATOM 2377 C C . GLY A 1 302 ? 42.464 97.976 49.108 1.00 26.24 ? 302 GLY A C 1 ATOM 2378 O O . GLY A 1 302 ? 41.249 98.087 49.067 1.00 24.97 ? 302 GLY A O 1 ATOM 2379 N N . THR A 1 303 ? 43.259 98.877 49.686 1.00 25.92 ? 303 THR A N 1 ATOM 2380 C CA . THR A 1 303 ? 42.732 100.075 50.343 1.00 26.04 ? 303 THR A CA 1 ATOM 2381 C C . THR A 1 303 ? 43.654 101.254 50.021 1.00 26.28 ? 303 THR A C 1 ATOM 2382 O O . THR A 1 303 ? 44.837 101.058 49.681 1.00 25.55 ? 303 THR A O 1 ATOM 2383 C CB . THR A 1 303 ? 42.731 99.937 51.892 1.00 25.59 ? 303 THR A CB 1 ATOM 2384 O OG1 . THR A 1 303 ? 44.069 99.729 52.328 1.00 27.74 ? 303 THR A OG1 1 ATOM 2385 C CG2 . THR A 1 303 ? 41.878 98.776 52.384 1.00 24.67 ? 303 THR A CG2 1 ATOM 2386 N N . LEU A 1 304 ? 43.114 102.465 50.147 1.00 26.23 ? 304 LEU A N 1 ATOM 2387 C CA . LEU A 1 304 ? 43.915 103.690 50.069 1.00 26.23 ? 304 LEU A CA 1 ATOM 2388 C C . LEU A 1 304 ? 45.073 103.767 51.093 1.00 26.22 ? 304 LEU A C 1 ATOM 2389 O O . LEU A 1 304 ? 46.149 104.255 50.758 1.00 25.87 ? 304 LEU A O 1 ATOM 2390 C CB . LEU A 1 304 ? 43.011 104.924 50.149 1.00 25.81 ? 304 LEU A CB 1 ATOM 2391 C CG . LEU A 1 304 ? 43.692 106.283 50.048 1.00 25.83 ? 304 LEU A CG 1 ATOM 2392 C CD1 . LEU A 1 304 ? 44.245 106.491 48.644 1.00 23.83 ? 304 LEU A CD1 1 ATOM 2393 C CD2 . LEU A 1 304 ? 42.714 107.409 50.411 1.00 25.79 ? 304 LEU A CD2 1 ATOM 2394 N N . ASP A 1 305 ? 44.849 103.290 52.317 1.00 26.15 ? 305 ASP A N 1 ATOM 2395 C CA . ASP A 1 305 ? 45.909 103.144 53.322 1.00 27.62 ? 305 ASP A CA 1 ATOM 2396 C C . ASP A 1 305 ? 47.126 102.381 52.776 1.00 26.71 ? 305 ASP A C 1 ATOM 2397 O O . ASP A 1 305 ? 48.249 102.803 52.962 1.00 26.96 ? 305 ASP A O 1 ATOM 2398 C CB . ASP A 1 305 ? 45.415 102.407 54.592 1.00 28.24 ? 305 ASP A CB 1 ATOM 2399 C CG . ASP A 1 305 ? 44.628 103.313 55.564 1.00 32.54 ? 305 ASP A CG 1 ATOM 2400 O OD1 . ASP A 1 305 ? 44.520 104.535 55.330 1.00 36.69 ? 305 ASP A OD1 1 ATOM 2401 O OD2 . ASP A 1 305 ? 44.119 102.778 56.583 1.00 38.34 ? 305 ASP A OD2 1 ATOM 2402 N N . ASN A 1 306 ? 46.883 101.241 52.156 1.00 26.54 ? 306 ASN A N 1 ATOM 2403 C CA . ASN A 1 306 ? 47.946 100.411 51.568 1.00 27.33 ? 306 ASN A CA 1 ATOM 2404 C C . ASN A 1 306 ? 48.589 101.097 50.388 1.00 26.89 ? 306 ASN A C 1 ATOM 2405 O O . ASN A 1 306 ? 49.787 100.994 50.229 1.00 27.60 ? 306 ASN A O 1 ATOM 2406 C CB . ASN A 1 306 ? 47.385 99.061 51.111 1.00 27.64 ? 306 ASN A CB 1 ATOM 2407 C CG . ASN A 1 306 ? 47.057 98.154 52.271 1.00 30.28 ? 306 ASN A CG 1 ATOM 2408 O OD1 . ASN A 1 306 ? 47.555 98.343 53.382 1.00 33.04 ? 306 ASN A OD1 1 ATOM 2409 N ND2 . ASN A 1 306 ? 46.229 97.154 52.021 1.00 30.36 ? 306 ASN A ND2 1 ATOM 2410 N N . MET A 1 307 ? 47.797 101.785 49.555 1.00 26.54 ? 307 MET A N 1 ATOM 2411 C CA . MET A 1 307 ? 48.357 102.546 48.429 1.00 26.83 ? 307 MET A CA 1 ATOM 2412 C C . MET A 1 307 ? 49.263 103.669 48.903 1.00 26.87 ? 307 MET A C 1 ATOM 2413 O O . MET A 1 307 ? 50.385 103.773 48.432 1.00 26.36 ? 307 MET A O 1 ATOM 2414 C CB . MET A 1 307 ? 47.260 103.110 47.511 1.00 26.49 ? 307 MET A CB 1 ATOM 2415 C CG . MET A 1 307 ? 47.800 103.770 46.258 1.00 25.54 ? 307 MET A CG 1 ATOM 2416 S SD . MET A 1 307 ? 46.531 104.607 45.299 1.00 29.35 ? 307 MET A SD 1 ATOM 2417 C CE . MET A 1 307 ? 45.695 103.242 44.473 1.00 29.59 ? 307 MET A CE 1 ATOM 2418 N N . ARG A 1 308 ? 48.757 104.520 49.809 1.00 27.02 ? 308 ARG A N 1 ATOM 2419 C CA . ARG A 1 308 ? 49.551 105.582 50.435 1.00 28.24 ? 308 ARG A CA 1 ATOM 2420 C C . ARG A 1 308 ? 50.839 105.067 51.089 1.00 27.15 ? 308 ARG A C 1 ATOM 2421 O O . ARG A 1 308 ? 51.870 105.709 51.010 1.00 27.36 ? 308 ARG A O 1 ATOM 2422 C CB . ARG A 1 308 ? 48.706 106.427 51.419 1.00 28.22 ? 308 ARG A CB 1 ATOM 2423 C CG . ARG A 1 308 ? 49.335 107.843 51.671 1.00 31.69 ? 308 ARG A CG 1 ATOM 2424 C CD . ARG A 1 308 ? 48.725 108.664 52.832 1.00 32.22 ? 308 ARG A CD 1 ATOM 2425 N NE . ARG A 1 308 ? 47.392 109.191 52.516 1.00 38.18 ? 308 ARG A NE 1 ATOM 2426 C CZ . ARG A 1 308 ? 46.268 108.548 52.805 1.00 40.57 ? 308 ARG A CZ 1 ATOM 2427 N NH1 . ARG A 1 308 ? 46.344 107.377 53.431 1.00 39.81 ? 308 ARG A NH1 1 ATOM 2428 N NH2 . ARG A 1 308 ? 45.085 109.070 52.480 1.00 40.53 ? 308 ARG A NH2 1 ATOM 2429 N N . GLU A 1 309 ? 50.779 103.905 51.725 1.00 27.32 ? 309 GLU A N 1 ATOM 2430 C CA . GLU A 1 309 ? 51.944 103.308 52.330 1.00 27.79 ? 309 GLU A CA 1 ATOM 2431 C C . GLU A 1 309 ? 53.059 103.036 51.288 1.00 26.79 ? 309 GLU A C 1 ATOM 2432 O O . GLU A 1 309 ? 54.234 103.350 51.523 1.00 25.58 ? 309 GLU A O 1 ATOM 2433 C CB . GLU A 1 309 ? 51.547 102.008 53.028 1.00 28.22 ? 309 GLU A CB 1 ATOM 2434 C CG . GLU A 1 309 ? 52.684 101.315 53.820 1.00 30.99 ? 309 GLU A CG 1 ATOM 2435 C CD . GLU A 1 309 ? 52.228 100.042 54.535 1.00 32.50 ? 309 GLU A CD 1 ATOM 2436 O OE1 . GLU A 1 309 ? 50.991 99.839 54.707 1.00 40.61 ? 309 GLU A OE1 1 ATOM 2437 O OE2 . GLU A 1 309 ? 53.117 99.230 54.928 1.00 39.51 ? 309 GLU A OE2 1 ATOM 2438 N N . VAL A 1 310 ? 52.688 102.423 50.166 1.00 25.13 ? 310 VAL A N 1 ATOM 2439 C CA . VAL A 1 310 ? 53.614 102.173 49.063 1.00 24.00 ? 310 VAL A CA 1 ATOM 2440 C C . VAL A 1 310 ? 54.169 103.495 48.505 1.00 23.54 ? 310 VAL A C 1 ATOM 2441 O O . VAL A 1 310 ? 55.372 103.631 48.330 1.00 23.64 ? 310 VAL A O 1 ATOM 2442 C CB . VAL A 1 310 ? 52.933 101.342 47.930 1.00 24.17 ? 310 VAL A CB 1 ATOM 2443 C CG1 . VAL A 1 310 ? 53.912 101.054 46.790 1.00 23.19 ? 310 VAL A CG1 1 ATOM 2444 C CG2 . VAL A 1 310 ? 52.349 100.023 48.510 1.00 25.00 ? 310 VAL A CG2 1 ATOM 2445 N N . VAL A 1 311 ? 53.290 104.456 48.228 1.00 23.28 ? 311 VAL A N 1 ATOM 2446 C CA . VAL A 1 311 ? 53.691 105.760 47.691 1.00 23.30 ? 311 VAL A CA 1 ATOM 2447 C C . VAL A 1 311 ? 54.717 106.395 48.635 1.00 24.32 ? 311 VAL A C 1 ATOM 2448 O O . VAL A 1 311 ? 55.752 106.861 48.209 1.00 24.61 ? 311 VAL A O 1 ATOM 2449 C CB . VAL A 1 311 ? 52.471 106.739 47.537 1.00 22.66 ? 311 VAL A CB 1 ATOM 2450 C CG1 . VAL A 1 311 ? 52.956 108.159 47.234 1.00 22.13 ? 311 VAL A CG1 1 ATOM 2451 C CG2 . VAL A 1 311 ? 51.453 106.259 46.473 1.00 20.80 ? 311 VAL A CG2 1 ATOM 2452 N N . GLU A 1 312 ? 54.423 106.391 49.936 1.00 25.44 ? 312 GLU A N 1 ATOM 2453 C CA A GLU A 1 312 ? 55.256 107.133 50.863 0.50 25.62 ? 312 GLU A CA 1 ATOM 2454 C CA B GLU A 1 312 ? 55.224 107.091 50.947 0.50 26.06 ? 312 GLU A CA 1 ATOM 2455 C C . GLU A 1 312 ? 56.610 106.473 51.112 1.00 25.84 ? 312 GLU A C 1 ATOM 2456 O O . GLU A 1 312 ? 57.610 107.183 51.267 1.00 26.46 ? 312 GLU A O 1 ATOM 2457 C CB A GLU A 1 312 ? 54.494 107.482 52.152 0.50 26.05 ? 312 GLU A CB 1 ATOM 2458 C CB B GLU A 1 312 ? 54.484 107.126 52.304 0.50 26.00 ? 312 GLU A CB 1 ATOM 2459 C CG A GLU A 1 312 ? 53.418 108.588 51.955 0.50 26.79 ? 312 GLU A CG 1 ATOM 2460 C CG B GLU A 1 312 ? 53.375 108.197 52.407 0.50 27.42 ? 312 GLU A CG 1 ATOM 2461 C CD A GLU A 1 312 ? 53.959 109.871 51.318 0.50 29.57 ? 312 GLU A CD 1 ATOM 2462 C CD B GLU A 1 312 ? 52.566 108.133 53.716 0.50 27.88 ? 312 GLU A CD 1 ATOM 2463 O OE1 A GLU A 1 312 ? 54.969 110.439 51.828 0.50 29.51 ? 312 GLU A OE1 1 ATOM 2464 O OE1 B GLU A 1 312 ? 52.748 107.185 54.520 0.50 29.96 ? 312 GLU A OE1 1 ATOM 2465 O OE2 A GLU A 1 312 ? 53.359 110.319 50.306 0.50 30.16 ? 312 GLU A OE2 1 ATOM 2466 O OE2 B GLU A 1 312 ? 51.723 109.033 53.931 0.50 31.07 ? 312 GLU A OE2 1 ATOM 2467 N N . ARG A 1 313 ? 56.686 105.138 51.092 1.00 24.86 ? 313 ARG A N 1 ATOM 2468 C CA . ARG A 1 313 ? 58.014 104.518 51.224 1.00 24.87 ? 313 ARG A CA 1 ATOM 2469 C C . ARG A 1 313 ? 58.918 104.730 49.979 1.00 24.39 ? 313 ARG A C 1 ATOM 2470 O O . ARG A 1 313 ? 60.144 104.760 50.092 1.00 24.63 ? 313 ARG A O 1 ATOM 2471 C CB . ARG A 1 313 ? 57.958 103.040 51.673 1.00 24.74 ? 313 ARG A CB 1 ATOM 2472 C CG . ARG A 1 313 ? 57.257 102.088 50.737 1.00 25.01 ? 313 ARG A CG 1 ATOM 2473 C CD . ARG A 1 313 ? 57.679 100.654 50.999 1.00 25.25 ? 313 ARG A CD 1 ATOM 2474 N NE . ARG A 1 313 ? 56.927 99.733 50.141 1.00 26.85 ? 313 ARG A NE 1 ATOM 2475 C CZ . ARG A 1 313 ? 55.956 98.909 50.545 1.00 27.65 ? 313 ARG A CZ 1 ATOM 2476 N NH1 . ARG A 1 313 ? 55.591 98.839 51.817 1.00 27.64 ? 313 ARG A NH1 1 ATOM 2477 N NH2 . ARG A 1 313 ? 55.338 98.135 49.650 1.00 27.61 ? 313 ARG A NH2 1 ATOM 2478 N N . ASN A 1 314 ? 58.315 104.910 48.802 1.00 24.07 ? 314 ASN A N 1 ATOM 2479 C CA . ASN A 1 314 ? 59.104 105.180 47.604 1.00 23.18 ? 314 ASN A CA 1 ATOM 2480 C C . ASN A 1 314 ? 59.518 106.632 47.508 1.00 23.31 ? 314 ASN A C 1 ATOM 2481 O O . ASN A 1 314 ? 60.620 106.925 47.063 1.00 22.43 ? 314 ASN A O 1 ATOM 2482 C CB . ASN A 1 314 ? 58.375 104.663 46.365 1.00 23.42 ? 314 ASN A CB 1 ATOM 2483 C CG . ASN A 1 314 ? 58.423 103.151 46.276 1.00 23.59 ? 314 ASN A CG 1 ATOM 2484 O OD1 . ASN A 1 314 ? 59.397 102.592 45.766 1.00 21.12 ? 314 ASN A OD1 1 ATOM 2485 N ND2 . ASN A 1 314 ? 57.414 102.476 46.843 1.00 21.23 ? 314 ASN A ND2 1 ATOM 2486 N N . ARG A 1 315 ? 58.643 107.548 47.947 1.00 23.69 ? 315 ARG A N 1 ATOM 2487 C CA . ARG A 1 315 ? 59.028 108.946 48.130 1.00 23.99 ? 315 ARG A CA 1 ATOM 2488 C C . ARG A 1 315 ? 60.135 109.145 49.181 1.00 24.43 ? 315 ARG A C 1 ATOM 2489 O O . ARG A 1 315 ? 61.044 109.929 48.974 1.00 24.16 ? 315 ARG A O 1 ATOM 2490 C CB . ARG A 1 315 ? 57.820 109.832 48.464 1.00 24.26 ? 315 ARG A CB 1 ATOM 2491 C CG . ARG A 1 315 ? 56.811 109.955 47.336 1.00 23.15 ? 315 ARG A CG 1 ATOM 2492 C CD . ARG A 1 315 ? 55.682 110.984 47.643 1.00 24.60 ? 315 ARG A CD 1 ATOM 2493 N NE . ARG A 1 315 ? 56.224 112.323 47.782 1.00 30.29 ? 315 ARG A NE 1 ATOM 2494 C CZ . ARG A 1 315 ? 56.454 112.957 48.943 1.00 34.08 ? 315 ARG A CZ 1 ATOM 2495 N NH1 . ARG A 1 315 ? 56.140 112.420 50.127 1.00 34.45 ? 315 ARG A NH1 1 ATOM 2496 N NH2 . ARG A 1 315 ? 56.970 114.173 48.912 1.00 35.36 ? 315 ARG A NH2 1 ATOM 2497 N N . ALA A 1 316 ? 60.050 108.427 50.295 1.00 24.66 ? 316 ALA A N 1 ATOM 2498 C CA . ALA A 1 316 ? 61.026 108.552 51.377 1.00 25.16 ? 316 ALA A CA 1 ATOM 2499 C C . ALA A 1 316 ? 62.406 108.086 50.886 1.00 25.27 ? 316 ALA A C 1 ATOM 2500 O O . ALA A 1 316 ? 63.442 108.589 51.327 1.00 25.72 ? 316 ALA A O 1 ATOM 2501 C CB . ALA A 1 316 ? 60.570 107.712 52.582 1.00 24.14 ? 316 ALA A CB 1 ATOM 2502 N N . ALA A 1 317 ? 62.403 107.145 49.945 1.00 25.09 ? 317 ALA A N 1 ATOM 2503 C CA . ALA A 1 317 ? 63.627 106.602 49.370 1.00 24.87 ? 317 ALA A CA 1 ATOM 2504 C C . ALA A 1 317 ? 64.243 107.486 48.270 1.00 24.50 ? 317 ALA A C 1 ATOM 2505 O O . ALA A 1 317 ? 65.230 107.092 47.666 1.00 24.01 ? 317 ALA A O 1 ATOM 2506 C CB . ALA A 1 317 ? 63.348 105.201 48.824 1.00 24.90 ? 317 ALA A CB 1 ATOM 2507 N N . GLN A 1 318 ? 63.646 108.653 48.009 1.00 23.73 ? 318 GLN A N 1 ATOM 2508 C CA . GLN A 1 318 ? 64.073 109.579 46.939 1.00 23.50 ? 318 GLN A CA 1 ATOM 2509 C C . GLN A 1 318 ? 64.095 108.922 45.547 1.00 23.27 ? 318 GLN A C 1 ATOM 2510 O O . GLN A 1 318 ? 64.963 109.201 44.713 1.00 23.83 ? 318 GLN A O 1 ATOM 2511 C CB . GLN A 1 318 ? 65.415 110.277 47.268 1.00 24.44 ? 318 GLN A CB 1 ATOM 2512 C CG . GLN A 1 318 ? 65.502 110.914 48.692 1.00 24.88 ? 318 GLN A CG 1 ATOM 2513 C CD . GLN A 1 318 ? 64.404 111.954 48.926 1.00 27.94 ? 318 GLN A CD 1 ATOM 2514 O OE1 . GLN A 1 318 ? 64.201 112.874 48.123 1.00 28.21 ? 318 GLN A OE1 1 ATOM 2515 N NE2 . GLN A 1 318 ? 63.670 111.791 50.019 1.00 33.49 ? 318 GLN A NE2 1 ATOM 2516 N N . LEU A 1 319 ? 63.124 108.054 45.291 1.00 21.89 ? 319 LEU A N 1 ATOM 2517 C CA . LEU A 1 319 ? 63.001 107.449 43.978 1.00 21.41 ? 319 LEU A CA 1 ATOM 2518 C C . LEU A 1 319 ? 62.408 108.459 42.970 1.00 20.69 ? 319 LEU A C 1 ATOM 2519 O O . LEU A 1 319 ? 61.438 109.153 43.303 1.00 20.48 ? 319 LEU A O 1 ATOM 2520 C CB . LEU A 1 319 ? 62.119 106.214 44.059 1.00 20.80 ? 319 LEU A CB 1 ATOM 2521 C CG . LEU A 1 319 ? 62.096 105.294 42.847 1.00 20.85 ? 319 LEU A CG 1 ATOM 2522 C CD1 . LEU A 1 319 ? 63.323 104.417 42.854 1.00 19.32 ? 319 LEU A CD1 1 ATOM 2523 C CD2 . LEU A 1 319 ? 60.832 104.434 42.913 1.00 19.21 ? 319 LEU A CD2 1 ATOM 2524 N N . PRO A 1 320 ? 63.012 108.561 41.758 1.00 20.32 ? 320 PRO A N 1 ATOM 2525 C CA . PRO A 1 320 ? 62.394 109.344 40.707 1.00 20.05 ? 320 PRO A CA 1 ATOM 2526 C C . PRO A 1 320 ? 61.075 108.643 40.377 1.00 20.45 ? 320 PRO A C 1 ATOM 2527 O O . PRO A 1 320 ? 61.072 107.455 40.036 1.00 19.84 ? 320 PRO A O 1 ATOM 2528 C CB . PRO A 1 320 ? 63.414 109.266 39.560 1.00 19.69 ? 320 PRO A CB 1 ATOM 2529 C CG . PRO A 1 320 ? 64.706 108.933 40.211 1.00 20.18 ? 320 PRO A CG 1 ATOM 2530 C CD . PRO A 1 320 ? 64.298 107.980 41.310 1.00 20.08 ? 320 PRO A CD 1 ATOM 2531 N N . TYR A 1 321 ? 59.961 109.371 40.515 1.00 19.71 ? 321 TYR A N 1 ATOM 2532 C CA . TYR A 1 321 ? 58.680 108.733 40.633 1.00 19.38 ? 321 TYR A CA 1 ATOM 2533 C C . TYR A 1 321 ? 57.612 109.779 40.372 1.00 19.87 ? 321 TYR A C 1 ATOM 2534 O O . TYR A 1 321 ? 57.241 110.559 41.271 1.00 19.32 ? 321 TYR A O 1 ATOM 2535 C CB . TYR A 1 321 ? 58.623 108.173 42.048 1.00 19.27 ? 321 TYR A CB 1 ATOM 2536 C CG . TYR A 1 321 ? 57.325 107.638 42.565 1.00 19.41 ? 321 TYR A CG 1 ATOM 2537 C CD1 . TYR A 1 321 ? 56.329 107.118 41.712 1.00 18.57 ? 321 TYR A CD1 1 ATOM 2538 C CD2 . TYR A 1 321 ? 57.106 107.603 43.936 1.00 19.96 ? 321 TYR A CD2 1 ATOM 2539 C CE1 . TYR A 1 321 ? 55.107 106.610 42.239 1.00 17.82 ? 321 TYR A CE1 1 ATOM 2540 C CE2 . TYR A 1 321 ? 55.909 107.096 44.469 1.00 20.85 ? 321 TYR A CE2 1 ATOM 2541 C CZ . TYR A 1 321 ? 54.930 106.604 43.617 1.00 21.42 ? 321 TYR A CZ 1 ATOM 2542 O OH . TYR A 1 321 ? 53.789 106.095 44.185 1.00 21.62 ? 321 TYR A OH 1 ATOM 2543 N N . ASP A 1 322 ? 57.133 109.813 39.128 1.00 19.72 ? 322 ASP A N 1 ATOM 2544 C CA . ASP A 1 322 ? 56.214 110.857 38.693 1.00 20.05 ? 322 ASP A CA 1 ATOM 2545 C C . ASP A 1 322 ? 54.752 110.449 38.757 1.00 19.86 ? 322 ASP A C 1 ATOM 2546 O O . ASP A 1 322 ? 53.896 111.314 38.974 1.00 19.07 ? 322 ASP A O 1 ATOM 2547 C CB . ASP A 1 322 ? 56.496 111.266 37.256 1.00 20.51 ? 322 ASP A CB 1 ATOM 2548 C CG . ASP A 1 322 ? 57.501 112.369 37.152 1.00 23.03 ? 322 ASP A CG 1 ATOM 2549 O OD1 . ASP A 1 322 ? 57.137 113.459 36.669 1.00 24.93 ? 322 ASP A OD1 1 ATOM 2550 O OD2 . ASP A 1 322 ? 58.653 112.125 37.543 1.00 23.19 ? 322 ASP A OD2 1 ATOM 2551 N N . VAL A 1 323 ? 54.455 109.164 38.514 1.00 19.54 ? 323 VAL A N 1 ATOM 2552 C CA . VAL A 1 323 ? 53.023 108.780 38.313 1.00 18.92 ? 323 VAL A CA 1 ATOM 2553 C C . VAL A 1 323 ? 52.640 107.572 39.150 1.00 19.26 ? 323 VAL A C 1 ATOM 2554 O O . VAL A 1 323 ? 53.375 106.579 39.197 1.00 19.08 ? 323 VAL A O 1 ATOM 2555 C CB . VAL A 1 323 ? 52.740 108.423 36.828 1.00 19.15 ? 323 VAL A CB 1 ATOM 2556 C CG1 . VAL A 1 323 ? 51.260 108.276 36.538 1.00 16.63 ? 323 VAL A CG1 1 ATOM 2557 C CG2 . VAL A 1 323 ? 53.402 109.419 35.847 1.00 16.29 ? 323 VAL A CG2 1 ATOM 2558 N N . GLN A 1 324 ? 51.483 107.663 39.803 1.00 18.68 ? 324 GLN A N 1 ATOM 2559 C CA . GLN A 1 324 ? 50.899 106.554 40.489 1.00 18.76 ? 324 GLN A CA 1 ATOM 2560 C C . GLN A 1 324 ? 49.655 106.145 39.731 1.00 19.04 ? 324 GLN A C 1 ATOM 2561 O O . GLN A 1 324 ? 48.810 106.996 39.395 1.00 19.75 ? 324 GLN A O 1 ATOM 2562 C CB . GLN A 1 324 ? 50.553 106.950 41.931 1.00 19.33 ? 324 GLN A CB 1 ATOM 2563 C CG . GLN A 1 324 ? 49.837 105.850 42.708 1.00 19.95 ? 324 GLN A CG 1 ATOM 2564 C CD . GLN A 1 324 ? 50.697 104.640 42.930 1.00 20.16 ? 324 GLN A CD 1 ATOM 2565 O OE1 . GLN A 1 324 ? 51.911 104.744 43.114 1.00 19.32 ? 324 GLN A OE1 1 ATOM 2566 N NE2 . GLN A 1 324 ? 50.079 103.475 42.910 1.00 18.83 ? 324 GLN A NE2 1 ATOM 2567 N N . HIS A 1 325 ? 49.525 104.844 39.453 1.00 18.65 ? 325 HIS A N 1 ATOM 2568 C CA . HIS A 1 325 ? 48.303 104.310 38.809 1.00 18.96 ? 325 HIS A CA 1 ATOM 2569 C C . HIS A 1 325 ? 47.379 103.707 39.854 1.00 19.27 ? 325 HIS A C 1 ATOM 2570 O O . HIS A 1 325 ? 47.831 103.216 40.880 1.00 20.01 ? 325 HIS A O 1 ATOM 2571 C CB . HIS A 1 325 ? 48.637 103.230 37.763 1.00 18.74 ? 325 HIS A CB 1 ATOM 2572 C CG . HIS A 1 325 ? 49.409 103.746 36.581 1.00 19.06 ? 325 HIS A CG 1 ATOM 2573 N ND1 . HIS A 1 325 ? 49.164 103.326 35.294 1.00 16.88 ? 325 HIS A ND1 1 ATOM 2574 C CD2 . HIS A 1 325 ? 50.398 104.669 36.491 1.00 18.77 ? 325 HIS A CD2 1 ATOM 2575 C CE1 . HIS A 1 325 ? 49.954 103.980 34.454 1.00 15.62 ? 325 HIS A CE1 1 ATOM 2576 N NE2 . HIS A 1 325 ? 50.720 104.794 35.158 1.00 19.01 ? 325 HIS A NE2 1 ATOM 2577 N N . ALA A 1 326 ? 46.079 103.737 39.579 1.00 19.36 ? 326 ALA A N 1 ATOM 2578 C CA . ALA A 1 326 ? 45.121 103.140 40.471 1.00 19.92 ? 326 ALA A CA 1 ATOM 2579 C C . ALA A 1 326 ? 44.300 102.180 39.629 1.00 19.65 ? 326 ALA A C 1 ATOM 2580 O O . ALA A 1 326 ? 43.655 102.591 38.669 1.00 19.36 ? 326 ALA A O 1 ATOM 2581 C CB . ALA A 1 326 ? 44.227 104.218 41.091 1.00 19.48 ? 326 ALA A CB 1 ATOM 2582 N N . ASP A 1 327 ? 44.330 100.919 40.031 1.00 20.54 ? 327 ASP A N 1 ATOM 2583 C CA . ASP A 1 327 ? 43.712 99.800 39.341 1.00 21.66 ? 327 ASP A CA 1 ATOM 2584 C C . ASP A 1 327 ? 42.271 99.649 39.885 1.00 22.47 ? 327 ASP A C 1 ATOM 2585 O O . ASP A 1 327 ? 41.818 100.503 40.652 1.00 22.50 ? 327 ASP A O 1 ATOM 2586 C CB . ASP A 1 327 ? 44.548 98.539 39.606 1.00 22.09 ? 327 ASP A CB 1 ATOM 2587 C CG . ASP A 1 327 ? 44.440 97.505 38.498 1.00 24.23 ? 327 ASP A CG 1 ATOM 2588 O OD1 . ASP A 1 327 ? 43.359 97.351 37.881 1.00 26.46 ? 327 ASP A OD1 1 ATOM 2589 O OD2 . ASP A 1 327 ? 45.447 96.825 38.253 1.00 22.02 ? 327 ASP A OD2 1 ATOM 2590 N N . ILE A 1 328 ? 41.565 98.587 39.475 1.00 22.14 ? 328 ILE A N 1 ATOM 2591 C CA . ILE A 1 328 ? 40.131 98.418 39.751 1.00 22.15 ? 328 ILE A CA 1 ATOM 2592 C C . ILE A 1 328 ? 39.721 98.385 41.223 1.00 22.91 ? 328 ILE A C 1 ATOM 2593 O O . ILE A 1 328 ? 38.558 98.624 41.498 1.00 23.57 ? 328 ILE A O 1 ATOM 2594 C CB . ILE A 1 328 ? 39.496 97.202 39.007 1.00 21.49 ? 328 ILE A CB 1 ATOM 2595 C CG1 . ILE A 1 328 ? 40.233 95.882 39.327 1.00 22.27 ? 328 ILE A CG1 1 ATOM 2596 C CG2 . ILE A 1 328 ? 39.416 97.468 37.536 1.00 19.11 ? 328 ILE A CG2 1 ATOM 2597 C CD1 . ILE A 1 328 ? 39.534 94.646 38.759 1.00 21.81 ? 328 ILE A CD1 1 ATOM 2598 N N . ASP A 1 329 ? 40.663 98.085 42.129 1.00 23.21 ? 329 ASP A N 1 ATOM 2599 C CA . ASP A 1 329 ? 40.446 98.191 43.583 1.00 24.79 ? 329 ASP A CA 1 ATOM 2600 C C . ASP A 1 329 ? 39.974 99.561 44.131 1.00 24.79 ? 329 ASP A C 1 ATOM 2601 O O . ASP A 1 329 ? 39.300 99.587 45.147 1.00 25.50 ? 329 ASP A O 1 ATOM 2602 C CB . ASP A 1 329 ? 41.592 97.555 44.444 1.00 24.61 ? 329 ASP A CB 1 ATOM 2603 C CG . ASP A 1 329 ? 42.994 98.041 44.072 1.00 26.60 ? 329 ASP A CG 1 ATOM 2604 O OD1 . ASP A 1 329 ? 43.367 98.019 42.887 1.00 29.01 ? 329 ASP A OD1 1 ATOM 2605 O OD2 . ASP A 1 329 ? 43.764 98.397 44.979 1.00 30.66 ? 329 ASP A OD2 1 ATOM 2606 N N . TYR A 1 330 ? 40.297 100.675 43.455 1.00 25.30 ? 330 TYR A N 1 ATOM 2607 C CA . TYR A 1 330 ? 39.735 102.012 43.814 1.00 24.51 ? 330 TYR A CA 1 ATOM 2608 C C . TYR A 1 330 ? 38.226 102.086 43.667 1.00 25.04 ? 330 TYR A C 1 ATOM 2609 O O . TYR A 1 330 ? 37.559 102.780 44.427 1.00 25.94 ? 330 TYR A O 1 ATOM 2610 C CB . TYR A 1 330 ? 40.409 103.194 43.080 1.00 23.74 ? 330 TYR A CB 1 ATOM 2611 C CG . TYR A 1 330 ? 39.952 103.502 41.650 1.00 24.24 ? 330 TYR A CG 1 ATOM 2612 C CD1 . TYR A 1 330 ? 38.742 104.162 41.400 1.00 22.69 ? 330 TYR A CD1 1 ATOM 2613 C CD2 . TYR A 1 330 ? 40.750 103.156 40.543 1.00 22.19 ? 330 TYR A CD2 1 ATOM 2614 C CE1 . TYR A 1 330 ? 38.314 104.436 40.111 1.00 20.96 ? 330 TYR A CE1 1 ATOM 2615 C CE2 . TYR A 1 330 ? 40.332 103.438 39.239 1.00 22.05 ? 330 TYR A CE2 1 ATOM 2616 C CZ . TYR A 1 330 ? 39.116 104.085 39.029 1.00 22.13 ? 330 TYR A CZ 1 ATOM 2617 O OH . TYR A 1 330 ? 38.692 104.371 37.746 1.00 21.16 ? 330 TYR A OH 1 ATOM 2618 N N . MET A 1 331 ? 37.686 101.358 42.702 1.00 24.92 ? 331 MET A N 1 ATOM 2619 C CA . MET A 1 331 ? 36.265 101.420 42.393 1.00 24.91 ? 331 MET A CA 1 ATOM 2620 C C . MET A 1 331 ? 35.365 100.866 43.511 1.00 25.06 ? 331 MET A C 1 ATOM 2621 O O . MET A 1 331 ? 35.785 100.077 44.336 1.00 23.87 ? 331 MET A O 1 ATOM 2622 C CB . MET A 1 331 ? 36.004 100.672 41.093 1.00 24.57 ? 331 MET A CB 1 ATOM 2623 C CG . MET A 1 331 ? 36.898 101.127 39.916 1.00 24.31 ? 331 MET A CG 1 ATOM 2624 S SD . MET A 1 331 ? 36.527 100.195 38.441 1.00 26.01 ? 331 MET A SD 1 ATOM 2625 C CE . MET A 1 331 ? 37.542 101.073 37.191 1.00 21.39 ? 331 MET A CE 1 ATOM 2626 N N . ASP A 1 332 ? 34.119 101.309 43.526 1.00 26.70 ? 332 ASP A N 1 ATOM 2627 C CA . ASP A 1 332 ? 33.100 100.668 44.343 1.00 28.71 ? 332 ASP A CA 1 ATOM 2628 C C . ASP A 1 332 ? 32.596 99.394 43.620 1.00 28.74 ? 332 ASP A C 1 ATOM 2629 O O . ASP A 1 332 ? 31.831 99.451 42.636 1.00 28.90 ? 332 ASP A O 1 ATOM 2630 C CB . ASP A 1 332 ? 31.958 101.656 44.650 1.00 29.32 ? 332 ASP A CB 1 ATOM 2631 C CG . ASP A 1 332 ? 30.839 101.026 45.479 1.00 31.65 ? 332 ASP A CG 1 ATOM 2632 O OD1 . ASP A 1 332 ? 31.046 99.966 46.107 1.00 33.64 ? 332 ASP A OD1 1 ATOM 2633 O OD2 . ASP A 1 332 ? 29.739 101.611 45.503 1.00 38.93 ? 332 ASP A OD2 1 ATOM 2634 N N . GLU A 1 333 ? 33.068 98.250 44.100 1.00 29.03 ? 333 GLU A N 1 ATOM 2635 C CA . GLU A 1 333 ? 32.731 96.932 43.500 1.00 29.19 ? 333 GLU A CA 1 ATOM 2636 C C . GLU A 1 333 ? 33.147 96.799 42.031 1.00 27.30 ? 333 GLU A C 1 ATOM 2637 O O . GLU A 1 333 ? 32.378 96.281 41.222 1.00 25.99 ? 333 GLU A O 1 ATOM 2638 C CB . GLU A 1 333 ? 31.237 96.632 43.636 1.00 30.97 ? 333 GLU A CB 1 ATOM 2639 C CG . GLU A 1 333 ? 30.647 96.940 45.021 1.00 35.86 ? 333 GLU A CG 1 ATOM 2640 C CD . GLU A 1 333 ? 30.795 95.800 45.986 1.00 44.08 ? 333 GLU A CD 1 ATOM 2641 O OE1 . GLU A 1 333 ? 31.874 95.145 46.013 1.00 47.66 ? 333 GLU A OE1 1 ATOM 2642 O OE2 . GLU A 1 333 ? 29.814 95.560 46.727 1.00 48.29 ? 333 GLU A OE2 1 ATOM 2643 N N . ARG A 1 334 ? 34.342 97.312 41.698 1.00 25.80 ? 334 ARG A N 1 ATOM 2644 C CA A ARG A 1 334 ? 34.899 97.184 40.338 0.50 25.32 ? 334 ARG A CA 1 ATOM 2645 C CA B ARG A 1 334 ? 34.907 97.198 40.351 0.50 25.31 ? 334 ARG A CA 1 ATOM 2646 C C . ARG A 1 334 ? 34.046 97.872 39.258 1.00 25.15 ? 334 ARG A C 1 ATOM 2647 O O . ARG A 1 334 ? 34.060 97.478 38.100 1.00 24.49 ? 334 ARG A O 1 ATOM 2648 C CB A ARG A 1 334 ? 35.135 95.707 39.965 0.50 24.54 ? 334 ARG A CB 1 ATOM 2649 C CB B ARG A 1 334 ? 35.240 95.725 40.055 0.50 24.60 ? 334 ARG A CB 1 ATOM 2650 C CG A ARG A 1 334 ? 36.212 94.989 40.780 0.50 24.13 ? 334 ARG A CG 1 ATOM 2651 C CG B ARG A 1 334 ? 36.274 95.190 41.054 0.50 23.89 ? 334 ARG A CG 1 ATOM 2652 C CD A ARG A 1 334 ? 35.612 94.096 41.840 0.50 23.64 ? 334 ARG A CD 1 ATOM 2653 C CD B ARG A 1 334 ? 36.506 93.705 40.964 0.50 23.37 ? 334 ARG A CD 1 ATOM 2654 N NE A ARG A 1 334 ? 34.512 93.292 41.311 0.50 22.79 ? 334 ARG A NE 1 ATOM 2655 N NE B ARG A 1 334 ? 37.778 93.346 41.590 0.50 23.10 ? 334 ARG A NE 1 ATOM 2656 C CZ A ARG A 1 334 ? 33.457 92.900 42.024 0.50 20.32 ? 334 ARG A CZ 1 ATOM 2657 C CZ B ARG A 1 334 ? 38.378 92.164 41.464 0.50 22.30 ? 334 ARG A CZ 1 ATOM 2658 N NH1 A ARG A 1 334 ? 33.358 93.236 43.306 0.50 18.20 ? 334 ARG A NH1 1 ATOM 2659 N NH1 B ARG A 1 334 ? 37.819 91.194 40.746 0.50 21.87 ? 334 ARG A NH1 1 ATOM 2660 N NH2 A ARG A 1 334 ? 32.512 92.164 41.453 0.50 18.88 ? 334 ARG A NH2 1 ATOM 2661 N NH2 B ARG A 1 334 ? 39.528 91.948 42.073 0.50 20.69 ? 334 ARG A NH2 1 ATOM 2662 N N . ARG A 1 335 ? 33.315 98.911 39.632 1.00 25.56 ? 335 ARG A N 1 ATOM 2663 C CA . ARG A 1 335 ? 32.487 99.607 38.657 1.00 26.73 ? 335 ARG A CA 1 ATOM 2664 C C . ARG A 1 335 ? 33.080 100.948 38.270 1.00 26.82 ? 335 ARG A C 1 ATOM 2665 O O . ARG A 1 335 ? 33.481 101.725 39.151 1.00 27.42 ? 335 ARG A O 1 ATOM 2666 C CB . ARG A 1 335 ? 31.064 99.780 39.188 1.00 26.98 ? 335 ARG A CB 1 ATOM 2667 C CG . ARG A 1 335 ? 30.257 98.465 39.220 1.00 29.73 ? 335 ARG A CG 1 ATOM 2668 C CD . ARG A 1 335 ? 28.839 98.736 39.671 1.00 34.68 ? 335 ARG A CD 1 ATOM 2669 N NE . ARG A 1 335 ? 28.935 99.461 40.921 1.00 37.21 ? 335 ARG A NE 1 ATOM 2670 C CZ . ARG A 1 335 ? 27.938 100.047 41.549 1.00 39.89 ? 335 ARG A CZ 1 ATOM 2671 N NH1 . ARG A 1 335 ? 26.691 99.990 41.053 1.00 36.53 ? 335 ARG A NH1 1 ATOM 2672 N NH2 . ARG A 1 335 ? 28.221 100.692 42.682 1.00 38.96 ? 335 ARG A NH2 1 ATOM 2673 N N . ASP A 1 336 ? 33.167 101.202 36.958 1.00 26.47 ? 336 ASP A N 1 ATOM 2674 C CA . ASP A 1 336 ? 33.681 102.465 36.427 1.00 25.75 ? 336 ASP A CA 1 ATOM 2675 C C . ASP A 1 336 ? 32.950 103.635 37.061 1.00 26.21 ? 336 ASP A C 1 ATOM 2676 O O . ASP A 1 336 ? 31.721 103.569 37.294 1.00 25.41 ? 336 ASP A O 1 ATOM 2677 C CB . ASP A 1 336 ? 33.394 102.595 34.923 1.00 25.80 ? 336 ASP A CB 1 ATOM 2678 C CG . ASP A 1 336 ? 34.389 101.852 34.032 1.00 26.96 ? 336 ASP A CG 1 ATOM 2679 O OD1 . ASP A 1 336 ? 35.408 101.360 34.533 1.00 22.88 ? 336 ASP A OD1 1 ATOM 2680 O OD2 . ASP A 1 336 ? 34.117 101.769 32.803 1.00 28.10 ? 336 ASP A OD2 1 ATOM 2681 N N . PHE A 1 337 ? 33.704 104.719 37.257 1.00 25.50 ? 337 PHE A N 1 ATOM 2682 C CA . PHE A 1 337 ? 33.178 106.058 37.590 1.00 26.32 ? 337 PHE A CA 1 ATOM 2683 C C . PHE A 1 337 ? 32.607 106.135 38.996 1.00 26.06 ? 337 PHE A C 1 ATOM 2684 O O . PHE A 1 337 ? 31.730 106.926 39.276 1.00 26.08 ? 337 PHE A O 1 ATOM 2685 C CB . PHE A 1 337 ? 32.219 106.616 36.503 1.00 25.26 ? 337 PHE A CB 1 ATOM 2686 C CG . PHE A 1 337 ? 32.783 106.523 35.097 1.00 25.63 ? 337 PHE A CG 1 ATOM 2687 C CD1 . PHE A 1 337 ? 33.956 107.214 34.748 1.00 23.38 ? 337 PHE A CD1 1 ATOM 2688 C CD2 . PHE A 1 337 ? 32.154 105.723 34.130 1.00 22.91 ? 337 PHE A CD2 1 ATOM 2689 C CE1 . PHE A 1 337 ? 34.496 107.103 33.446 1.00 22.23 ? 337 PHE A CE1 1 ATOM 2690 C CE2 . PHE A 1 337 ? 32.693 105.598 32.853 1.00 23.07 ? 337 PHE A CE2 1 ATOM 2691 C CZ . PHE A 1 337 ? 33.854 106.310 32.504 1.00 22.32 ? 337 PHE A CZ 1 ATOM 2692 N N . THR A 1 338 ? 33.169 105.309 39.873 1.00 26.92 ? 338 THR A N 1 ATOM 2693 C CA . THR A 1 338 ? 32.828 105.281 41.297 1.00 27.17 ? 338 THR A CA 1 ATOM 2694 C C . THR A 1 338 ? 34.156 105.072 42.037 1.00 27.18 ? 338 THR A C 1 ATOM 2695 O O . THR A 1 338 ? 35.108 104.590 41.444 1.00 25.98 ? 338 THR A O 1 ATOM 2696 C CB . THR A 1 338 ? 31.960 104.053 41.652 1.00 27.00 ? 338 THR A CB 1 ATOM 2697 O OG1 . THR A 1 338 ? 32.759 102.871 41.562 1.00 27.22 ? 338 THR A OG1 1 ATOM 2698 C CG2 . THR A 1 338 ? 30.709 103.918 40.753 1.00 27.17 ? 338 THR A CG2 1 ATOM 2699 N N . TYR A 1 339 ? 34.219 105.403 43.321 1.00 27.27 ? 339 TYR A N 1 ATOM 2700 C CA . TYR A 1 339 ? 35.302 104.881 44.150 1.00 28.65 ? 339 TYR A CA 1 ATOM 2701 C C . TYR A 1 339 ? 34.715 104.340 45.443 1.00 29.39 ? 339 TYR A C 1 ATOM 2702 O O . TYR A 1 339 ? 33.602 104.700 45.830 1.00 30.46 ? 339 TYR A O 1 ATOM 2703 C CB . TYR A 1 339 ? 36.421 105.911 44.356 1.00 29.00 ? 339 TYR A CB 1 ATOM 2704 C CG . TYR A 1 339 ? 36.054 107.083 45.242 1.00 30.92 ? 339 TYR A CG 1 ATOM 2705 C CD1 . TYR A 1 339 ? 36.372 107.076 46.616 1.00 32.08 ? 339 TYR A CD1 1 ATOM 2706 C CD2 . TYR A 1 339 ? 35.422 108.198 44.719 1.00 31.03 ? 339 TYR A CD2 1 ATOM 2707 C CE1 . TYR A 1 339 ? 36.052 108.155 47.438 1.00 34.40 ? 339 TYR A CE1 1 ATOM 2708 C CE2 . TYR A 1 339 ? 35.081 109.283 45.539 1.00 32.76 ? 339 TYR A CE2 1 ATOM 2709 C CZ . TYR A 1 339 ? 35.402 109.247 46.888 1.00 32.91 ? 339 TYR A CZ 1 ATOM 2710 O OH . TYR A 1 339 ? 35.084 110.309 47.687 1.00 35.44 ? 339 TYR A OH 1 ATOM 2711 N N . ASP A 1 340 ? 35.444 103.444 46.090 1.00 30.05 ? 340 ASP A N 1 ATOM 2712 C CA . ASP A 1 340 ? 34.973 102.760 47.278 1.00 30.47 ? 340 ASP A CA 1 ATOM 2713 C C . ASP A 1 340 ? 35.040 103.736 48.471 1.00 30.81 ? 340 ASP A C 1 ATOM 2714 O O . ASP A 1 340 ? 36.124 104.108 48.941 1.00 30.02 ? 340 ASP A O 1 ATOM 2715 C CB . ASP A 1 340 ? 35.839 101.516 47.462 1.00 31.00 ? 340 ASP A CB 1 ATOM 2716 C CG . ASP A 1 340 ? 35.391 100.632 48.602 1.00 32.70 ? 340 ASP A CG 1 ATOM 2717 O OD1 . ASP A 1 340 ? 34.659 101.092 49.485 1.00 37.49 ? 340 ASP A OD1 1 ATOM 2718 O OD2 . ASP A 1 340 ? 35.796 99.459 48.623 1.00 36.15 ? 340 ASP A OD2 1 ATOM 2719 N N . SER A 1 341 ? 33.872 104.175 48.934 1.00 31.19 ? 341 SER A N 1 ATOM 2720 C CA . SER A 1 341 ? 33.754 105.174 50.012 1.00 31.75 ? 341 SER A CA 1 ATOM 2721 C C . SER A 1 341 ? 34.287 104.699 51.366 1.00 31.63 ? 341 SER A C 1 ATOM 2722 O O . SER A 1 341 ? 34.520 105.518 52.251 1.00 33.02 ? 341 SER A O 1 ATOM 2723 C CB . SER A 1 341 ? 32.290 105.592 50.164 1.00 32.26 ? 341 SER A CB 1 ATOM 2724 O OG . SER A 1 341 ? 31.517 104.463 50.580 1.00 32.37 ? 341 SER A OG 1 ATOM 2725 N N . VAL A 1 342 ? 34.483 103.391 51.536 1.00 31.68 ? 342 VAL A N 1 ATOM 2726 C CA . VAL A 1 342 ? 35.066 102.836 52.775 1.00 31.55 ? 342 VAL A CA 1 ATOM 2727 C C . VAL A 1 342 ? 36.548 102.566 52.545 1.00 31.00 ? 342 VAL A C 1 ATOM 2728 O O . VAL A 1 342 ? 37.418 103.217 53.126 1.00 31.11 ? 342 VAL A O 1 ATOM 2729 C CB . VAL A 1 342 ? 34.323 101.542 53.277 1.00 31.38 ? 342 VAL A CB 1 ATOM 2730 C CG1 . VAL A 1 342 ? 35.083 100.847 54.447 1.00 31.23 ? 342 VAL A CG1 1 ATOM 2731 C CG2 . VAL A 1 342 ? 32.883 101.850 53.659 1.00 32.61 ? 342 VAL A CG2 1 ATOM 2732 N N . ASP A 1 343 ? 36.858 101.614 51.678 1.00 30.92 ? 343 ASP A N 1 ATOM 2733 C CA . ASP A 1 343 ? 38.265 101.237 51.489 1.00 30.01 ? 343 ASP A CA 1 ATOM 2734 C C . ASP A 1 343 ? 39.112 102.351 50.870 1.00 28.71 ? 343 ASP A C 1 ATOM 2735 O O . ASP A 1 343 ? 40.316 102.423 51.152 1.00 28.90 ? 343 ASP A O 1 ATOM 2736 C CB . ASP A 1 343 ? 38.379 99.938 50.707 1.00 30.79 ? 343 ASP A CB 1 ATOM 2737 C CG . ASP A 1 343 ? 38.071 98.707 51.561 1.00 32.88 ? 343 ASP A CG 1 ATOM 2738 O OD1 . ASP A 1 343 ? 37.657 98.852 52.729 1.00 36.59 ? 343 ASP A OD1 1 ATOM 2739 O OD2 . ASP A 1 343 ? 38.273 97.580 51.061 1.00 34.45 ? 343 ASP A OD2 1 ATOM 2740 N N . PHE A 1 344 ? 38.484 103.220 50.071 1.00 26.70 ? 344 PHE A N 1 ATOM 2741 C CA . PHE A 1 344 ? 39.156 104.401 49.482 1.00 26.38 ? 344 PHE A CA 1 ATOM 2742 C C . PHE A 1 344 ? 38.520 105.729 49.969 1.00 26.90 ? 344 PHE A C 1 ATOM 2743 O O . PHE A 1 344 ? 38.484 106.734 49.237 1.00 26.75 ? 344 PHE A O 1 ATOM 2744 C CB . PHE A 1 344 ? 39.205 104.327 47.943 1.00 25.64 ? 344 PHE A CB 1 ATOM 2745 C CG . PHE A 1 344 ? 40.323 103.448 47.410 1.00 26.28 ? 344 PHE A CG 1 ATOM 2746 C CD1 . PHE A 1 344 ? 40.263 102.062 47.534 1.00 25.89 ? 344 PHE A CD1 1 ATOM 2747 C CD2 . PHE A 1 344 ? 41.451 104.018 46.825 1.00 26.65 ? 344 PHE A CD2 1 ATOM 2748 C CE1 . PHE A 1 344 ? 41.299 101.245 47.076 1.00 27.11 ? 344 PHE A CE1 1 ATOM 2749 C CE2 . PHE A 1 344 ? 42.527 103.210 46.382 1.00 27.34 ? 344 PHE A CE2 1 ATOM 2750 C CZ . PHE A 1 344 ? 42.442 101.825 46.501 1.00 26.74 ? 344 PHE A CZ 1 ATOM 2751 N N . LYS A 1 345 ? 38.026 105.715 51.215 1.00 27.73 ? 345 LYS A N 1 ATOM 2752 C CA . LYS A 1 345 ? 37.583 106.932 51.917 1.00 28.39 ? 345 LYS A CA 1 ATOM 2753 C C . LYS A 1 345 ? 38.780 107.846 51.951 1.00 27.93 ? 345 LYS A C 1 ATOM 2754 O O . LYS A 1 345 ? 39.877 107.436 52.377 1.00 27.58 ? 345 LYS A O 1 ATOM 2755 C CB . LYS A 1 345 ? 37.160 106.617 53.360 1.00 28.87 ? 345 LYS A CB 1 ATOM 2756 C CG . LYS A 1 345 ? 36.833 107.852 54.211 1.00 30.54 ? 345 LYS A CG 1 ATOM 2757 C CD . LYS A 1 345 ? 36.348 107.468 55.606 1.00 30.84 ? 345 LYS A CD 1 ATOM 2758 C CE . LYS A 1 345 ? 36.014 108.729 56.442 1.00 35.81 ? 345 LYS A CE 1 ATOM 2759 N NZ . LYS A 1 345 ? 35.628 108.388 57.867 1.00 38.77 ? 345 LYS A NZ 1 ATOM 2760 N N . GLY A 1 346 ? 38.596 109.074 51.493 1.00 27.47 ? 346 GLY A N 1 ATOM 2761 C CA . GLY A 1 346 ? 39.701 110.015 51.560 1.00 28.19 ? 346 GLY A CA 1 ATOM 2762 C C . GLY A 1 346 ? 40.464 110.135 50.249 1.00 27.16 ? 346 GLY A C 1 ATOM 2763 O O . GLY A 1 346 ? 41.427 110.862 50.196 1.00 26.04 ? 346 GLY A O 1 ATOM 2764 N N . PHE A 1 347 ? 39.985 109.464 49.197 1.00 27.56 ? 347 PHE A N 1 ATOM 2765 C CA . PHE A 1 347 ? 40.619 109.510 47.858 1.00 27.67 ? 347 PHE A CA 1 ATOM 2766 C C . PHE A 1 347 ? 40.926 110.925 47.336 1.00 27.77 ? 347 PHE A C 1 ATOM 2767 O O . PHE A 1 347 ? 42.089 111.181 46.970 1.00 27.93 ? 347 PHE A O 1 ATOM 2768 C CB . PHE A 1 347 ? 39.831 108.692 46.811 1.00 27.78 ? 347 PHE A CB 1 ATOM 2769 C CG . PHE A 1 347 ? 40.691 108.108 45.677 1.00 28.40 ? 347 PHE A CG 1 ATOM 2770 C CD1 . PHE A 1 347 ? 42.090 108.014 45.790 1.00 29.06 ? 347 PHE A CD1 1 ATOM 2771 C CD2 . PHE A 1 347 ? 40.081 107.590 44.526 1.00 28.54 ? 347 PHE A CD2 1 ATOM 2772 C CE1 . PHE A 1 347 ? 42.887 107.446 44.744 1.00 28.62 ? 347 PHE A CE1 1 ATOM 2773 C CE2 . PHE A 1 347 ? 40.848 107.022 43.504 1.00 27.92 ? 347 PHE A CE2 1 ATOM 2774 C CZ . PHE A 1 347 ? 42.266 106.975 43.612 1.00 27.86 ? 347 PHE A CZ 1 ATOM 2775 N N . PRO A 1 348 ? 39.923 111.856 47.319 1.00 27.41 ? 348 PRO A N 1 ATOM 2776 C CA . PRO A 1 348 ? 40.187 113.209 46.807 1.00 27.19 ? 348 PRO A CA 1 ATOM 2777 C C . PRO A 1 348 ? 41.299 113.949 47.565 1.00 27.61 ? 348 PRO A C 1 ATOM 2778 O O . PRO A 1 348 ? 42.112 114.656 46.953 1.00 28.70 ? 348 PRO A O 1 ATOM 2779 C CB . PRO A 1 348 ? 38.836 113.913 46.975 1.00 27.34 ? 348 PRO A CB 1 ATOM 2780 C CG . PRO A 1 348 ? 37.848 112.796 46.963 1.00 25.08 ? 348 PRO A CG 1 ATOM 2781 C CD . PRO A 1 348 ? 38.512 111.737 47.747 1.00 27.44 ? 348 PRO A CD 1 ATOM 2782 N N . GLU A 1 349 ? 41.365 113.754 48.867 1.00 27.53 ? 349 GLU A N 1 ATOM 2783 C CA A GLU A 1 349 ? 42.404 114.369 49.690 0.50 27.77 ? 349 GLU A CA 1 ATOM 2784 C CA B GLU A 1 349 ? 42.407 114.372 49.667 0.50 27.98 ? 349 GLU A CA 1 ATOM 2785 C C . GLU A 1 349 ? 43.792 113.778 49.353 1.00 27.74 ? 349 GLU A C 1 ATOM 2786 O O . GLU A 1 349 ? 44.808 114.507 49.323 1.00 27.76 ? 349 GLU A O 1 ATOM 2787 C CB A GLU A 1 349 ? 42.076 114.210 51.186 0.50 27.82 ? 349 GLU A CB 1 ATOM 2788 C CB B GLU A 1 349 ? 42.056 114.255 51.152 0.50 28.12 ? 349 GLU A CB 1 ATOM 2789 C CG A GLU A 1 349 ? 40.767 114.892 51.677 0.50 28.54 ? 349 GLU A CG 1 ATOM 2790 C CG B GLU A 1 349 ? 42.917 115.076 52.082 0.50 30.01 ? 349 GLU A CG 1 ATOM 2791 C CD A GLU A 1 349 ? 39.563 113.936 51.830 0.50 30.60 ? 349 GLU A CD 1 ATOM 2792 C CD B GLU A 1 349 ? 43.565 116.241 51.396 0.50 32.54 ? 349 GLU A CD 1 ATOM 2793 O OE1 A GLU A 1 349 ? 39.126 113.319 50.816 0.50 25.93 ? 349 GLU A OE1 1 ATOM 2794 O OE1 B GLU A 1 349 ? 42.847 117.132 50.899 0.50 35.46 ? 349 GLU A OE1 1 ATOM 2795 O OE2 A GLU A 1 349 ? 39.040 113.831 52.980 0.50 29.89 ? 349 GLU A OE2 1 ATOM 2796 O OE2 B GLU A 1 349 ? 44.810 116.264 51.343 0.50 33.77 ? 349 GLU A OE2 1 ATOM 2797 N N . PHE A 1 350 ? 43.844 112.466 49.111 1.00 27.38 ? 350 PHE A N 1 ATOM 2798 C CA . PHE A 1 350 ? 45.091 111.775 48.675 1.00 27.03 ? 350 PHE A CA 1 ATOM 2799 C C . PHE A 1 350 ? 45.588 112.306 47.318 1.00 26.20 ? 350 PHE A C 1 ATOM 2800 O O . PHE A 1 350 ? 46.793 112.495 47.109 1.00 25.23 ? 350 PHE A O 1 ATOM 2801 C CB . PHE A 1 350 ? 44.879 110.250 48.610 1.00 28.06 ? 350 PHE A CB 1 ATOM 2802 C CG . PHE A 1 350 ? 45.974 109.497 47.861 1.00 29.15 ? 350 PHE A CG 1 ATOM 2803 C CD1 . PHE A 1 350 ? 47.168 109.176 48.478 1.00 30.19 ? 350 PHE A CD1 1 ATOM 2804 C CD2 . PHE A 1 350 ? 45.799 109.128 46.529 1.00 30.43 ? 350 PHE A CD2 1 ATOM 2805 C CE1 . PHE A 1 350 ? 48.181 108.466 47.788 1.00 30.18 ? 350 PHE A CE1 1 ATOM 2806 C CE2 . PHE A 1 350 ? 46.792 108.436 45.845 1.00 29.35 ? 350 PHE A CE2 1 ATOM 2807 C CZ . PHE A 1 350 ? 47.984 108.097 46.491 1.00 29.49 ? 350 PHE A CZ 1 ATOM 2808 N N . VAL A 1 351 ? 44.651 112.579 46.408 1.00 26.19 ? 351 VAL A N 1 ATOM 2809 C CA . VAL A 1 351 ? 45.002 113.133 45.100 1.00 25.28 ? 351 VAL A CA 1 ATOM 2810 C C . VAL A 1 351 ? 45.625 114.527 45.236 1.00 24.46 ? 351 VAL A C 1 ATOM 2811 O O . VAL A 1 351 ? 46.598 114.841 44.543 1.00 22.70 ? 351 VAL A O 1 ATOM 2812 C CB . VAL A 1 351 ? 43.821 113.134 44.142 1.00 26.62 ? 351 VAL A CB 1 ATOM 2813 C CG1 . VAL A 1 351 ? 44.214 113.779 42.816 1.00 27.24 ? 351 VAL A CG1 1 ATOM 2814 C CG2 . VAL A 1 351 ? 43.327 111.675 43.900 1.00 26.27 ? 351 VAL A CG2 1 ATOM 2815 N N . ASN A 1 352 ? 45.081 115.348 46.150 1.00 23.07 ? 352 ASN A N 1 ATOM 2816 C CA . ASN A 1 352 ? 45.653 116.658 46.450 1.00 21.75 ? 352 ASN A CA 1 ATOM 2817 C C . ASN A 1 352 ? 47.089 116.482 46.921 1.00 21.57 ? 352 ASN A C 1 ATOM 2818 O O . ASN A 1 352 ? 47.969 117.203 46.464 1.00 21.49 ? 352 ASN A O 1 ATOM 2819 C CB . ASN A 1 352 ? 44.837 117.387 47.524 1.00 20.95 ? 352 ASN A CB 1 ATOM 2820 C CG . ASN A 1 352 ? 43.473 117.890 47.016 1.00 21.84 ? 352 ASN A CG 1 ATOM 2821 O OD1 . ASN A 1 352 ? 43.175 117.859 45.816 1.00 23.21 ? 352 ASN A OD1 1 ATOM 2822 N ND2 . ASN A 1 352 ? 42.672 118.408 47.932 1.00 20.01 ? 352 ASN A ND2 1 ATOM 2823 N N . GLU A 1 353 ? 47.300 115.541 47.837 1.00 21.39 ? 353 GLU A N 1 ATOM 2824 C CA A GLU A 1 353 ? 48.640 115.199 48.356 0.50 22.58 ? 353 GLU A CA 1 ATOM 2825 C CA B GLU A 1 353 ? 48.644 115.222 48.348 0.50 22.61 ? 353 GLU A CA 1 ATOM 2826 C C . GLU A 1 353 ? 49.600 114.811 47.222 1.00 22.13 ? 353 GLU A C 1 ATOM 2827 O O . GLU A 1 353 ? 50.746 115.282 47.176 1.00 22.98 ? 353 GLU A O 1 ATOM 2828 C CB A GLU A 1 353 ? 48.561 114.066 49.411 0.50 22.11 ? 353 GLU A CB 1 ATOM 2829 C CB B GLU A 1 353 ? 48.593 114.140 49.450 0.50 22.13 ? 353 GLU A CB 1 ATOM 2830 C CG A GLU A 1 353 ? 47.758 114.408 50.681 0.50 23.57 ? 353 GLU A CG 1 ATOM 2831 C CG B GLU A 1 353 ? 49.964 113.768 50.000 0.50 23.25 ? 353 GLU A CG 1 ATOM 2832 C CD A GLU A 1 353 ? 47.393 113.183 51.539 0.50 24.30 ? 353 GLU A CD 1 ATOM 2833 C CD B GLU A 1 353 ? 49.923 112.877 51.237 0.50 24.72 ? 353 GLU A CD 1 ATOM 2834 O OE1 A GLU A 1 353 ? 46.681 113.370 52.548 0.50 27.66 ? 353 GLU A OE1 1 ATOM 2835 O OE1 B GLU A 1 353 ? 49.505 113.375 52.308 0.50 26.90 ? 353 GLU A OE1 1 ATOM 2836 O OE2 A GLU A 1 353 ? 47.793 112.042 51.210 0.50 24.94 ? 353 GLU A OE2 1 ATOM 2837 O OE2 B GLU A 1 353 ? 50.351 111.696 51.148 0.50 27.17 ? 353 GLU A OE2 1 ATOM 2838 N N . LEU A 1 354 ? 49.131 113.949 46.325 1.00 21.72 ? 354 LEU A N 1 ATOM 2839 C CA . LEU A 1 354 ? 49.893 113.519 45.137 1.00 22.20 ? 354 LEU A CA 1 ATOM 2840 C C . LEU A 1 354 ? 50.327 114.694 44.294 1.00 21.98 ? 354 LEU A C 1 ATOM 2841 O O . LEU A 1 354 ? 51.504 114.819 43.939 1.00 21.70 ? 354 LEU A O 1 ATOM 2842 C CB . LEU A 1 354 ? 49.071 112.610 44.220 1.00 21.89 ? 354 LEU A CB 1 ATOM 2843 C CG . LEU A 1 354 ? 49.239 111.095 44.271 1.00 24.47 ? 354 LEU A CG 1 ATOM 2844 C CD1 . LEU A 1 354 ? 48.431 110.557 43.118 1.00 24.32 ? 354 LEU A CD1 1 ATOM 2845 C CD2 . LEU A 1 354 ? 50.681 110.606 44.170 1.00 22.12 ? 354 LEU A CD2 1 ATOM 2846 N N . HIS A 1 355 ? 49.363 115.539 43.963 1.00 21.98 ? 355 HIS A N 1 ATOM 2847 C CA . HIS A 1 355 ? 49.588 116.723 43.159 1.00 23.21 ? 355 HIS A CA 1 ATOM 2848 C C . HIS A 1 355 ? 50.556 117.703 43.800 1.00 23.99 ? 355 HIS A C 1 ATOM 2849 O O . HIS A 1 355 ? 51.440 118.236 43.116 1.00 24.50 ? 355 HIS A O 1 ATOM 2850 C CB . HIS A 1 355 ? 48.236 117.382 42.846 1.00 24.11 ? 355 HIS A CB 1 ATOM 2851 C CG . HIS A 1 355 ? 47.420 116.603 41.852 1.00 25.45 ? 355 HIS A CG 1 ATOM 2852 N ND1 . HIS A 1 355 ? 46.070 116.810 41.652 1.00 26.47 ? 355 HIS A ND1 1 ATOM 2853 C CD2 . HIS A 1 355 ? 47.780 115.623 40.989 1.00 25.26 ? 355 HIS A CD2 1 ATOM 2854 C CE1 . HIS A 1 355 ? 45.631 115.981 40.721 1.00 26.44 ? 355 HIS A CE1 1 ATOM 2855 N NE2 . HIS A 1 355 ? 46.651 115.253 40.295 1.00 26.10 ? 355 HIS A NE2 1 ATOM 2856 N N . ASN A 1 356 ? 50.376 117.935 45.103 1.00 23.26 ? 356 ASN A N 1 ATOM 2857 C CA A ASN A 1 356 ? 51.241 118.819 45.883 0.50 24.15 ? 356 ASN A CA 1 ATOM 2858 C CA B ASN A 1 356 ? 51.255 118.815 45.861 0.50 23.43 ? 356 ASN A CA 1 ATOM 2859 C C . ASN A 1 356 ? 52.687 118.299 45.961 1.00 23.98 ? 356 ASN A C 1 ATOM 2860 O O . ASN A 1 356 ? 53.613 119.073 46.119 1.00 24.89 ? 356 ASN A O 1 ATOM 2861 C CB A ASN A 1 356 ? 50.677 119.008 47.298 0.50 23.58 ? 356 ASN A CB 1 ATOM 2862 C CB B ASN A 1 356 ? 50.680 119.044 47.251 0.50 22.20 ? 356 ASN A CB 1 ATOM 2863 C CG A ASN A 1 356 ? 51.328 120.167 48.037 0.50 24.42 ? 356 ASN A CG 1 ATOM 2864 C CG B ASN A 1 356 ? 49.529 119.994 47.229 0.50 20.08 ? 356 ASN A CG 1 ATOM 2865 O OD1 A ASN A 1 356 ? 51.151 121.329 47.666 0.50 25.38 ? 356 ASN A OD1 1 ATOM 2866 O OD1 B ASN A 1 356 ? 49.319 120.705 46.248 0.50 16.52 ? 356 ASN A OD1 1 ATOM 2867 N ND2 A ASN A 1 356 ? 52.078 119.858 49.097 0.50 23.63 ? 356 ASN A ND2 1 ATOM 2868 N ND2 B ASN A 1 356 ? 48.777 120.027 48.307 0.50 16.39 ? 356 ASN A ND2 1 ATOM 2869 N N . ASN A 1 357 ? 52.858 116.981 45.868 1.00 24.50 ? 357 ASN A N 1 ATOM 2870 C CA . ASN A 1 357 ? 54.180 116.354 45.781 1.00 25.02 ? 357 ASN A CA 1 ATOM 2871 C C . ASN A 1 357 ? 54.754 116.298 44.337 1.00 24.61 ? 357 ASN A C 1 ATOM 2872 O O . ASN A 1 357 ? 55.767 115.642 44.082 1.00 25.93 ? 357 ASN A O 1 ATOM 2873 C CB . ASN A 1 357 ? 54.131 114.964 46.409 1.00 25.27 ? 357 ASN A CB 1 ATOM 2874 C CG . ASN A 1 357 ? 53.907 115.007 47.944 1.00 28.41 ? 357 ASN A CG 1 ATOM 2875 O OD1 . ASN A 1 357 ? 53.175 114.207 48.491 1.00 32.39 ? 357 ASN A OD1 1 ATOM 2876 N ND2 . ASN A 1 357 ? 54.556 115.926 48.616 1.00 29.43 ? 357 ASN A ND2 1 ATOM 2877 N N . GLY A 1 358 ? 54.115 116.984 43.398 1.00 24.04 ? 358 GLY A N 1 ATOM 2878 C CA . GLY A 1 358 ? 54.536 116.992 41.997 1.00 22.89 ? 358 GLY A CA 1 ATOM 2879 C C . GLY A 1 358 ? 54.261 115.710 41.209 1.00 23.05 ? 358 GLY A C 1 ATOM 2880 O O . GLY A 1 358 ? 54.821 115.500 40.121 1.00 24.07 ? 358 GLY A O 1 ATOM 2881 N N . GLN A 1 359 ? 53.430 114.832 41.750 1.00 21.40 ? 359 GLN A N 1 ATOM 2882 C CA . GLN A 1 359 ? 53.131 113.575 41.085 1.00 20.82 ? 359 GLN A CA 1 ATOM 2883 C C . GLN A 1 359 ? 51.800 113.617 40.328 1.00 20.12 ? 359 GLN A C 1 ATOM 2884 O O . GLN A 1 359 ? 51.090 114.611 40.384 1.00 18.55 ? 359 GLN A O 1 ATOM 2885 C CB . GLN A 1 359 ? 53.140 112.478 42.105 1.00 20.99 ? 359 GLN A CB 1 ATOM 2886 C CG . GLN A 1 359 ? 54.528 112.200 42.562 1.00 23.64 ? 359 GLN A CG 1 ATOM 2887 C CD . GLN A 1 359 ? 54.532 111.221 43.677 1.00 25.05 ? 359 GLN A CD 1 ATOM 2888 O OE1 . GLN A 1 359 ? 53.831 111.415 44.681 1.00 23.42 ? 359 GLN A OE1 1 ATOM 2889 N NE2 . GLN A 1 359 ? 55.318 110.148 43.526 1.00 22.98 ? 359 GLN A NE2 1 ATOM 2890 N N . LYS A 1 360 ? 51.499 112.550 39.583 1.00 20.44 ? 360 LYS A N 1 ATOM 2891 C CA . LYS A 1 360 ? 50.266 112.480 38.791 1.00 20.40 ? 360 LYS A CA 1 ATOM 2892 C C . LYS A 1 360 ? 49.501 111.202 39.068 1.00 19.71 ? 360 LYS A C 1 ATOM 2893 O O . LYS A 1 360 ? 50.093 110.214 39.488 1.00 20.15 ? 360 LYS A O 1 ATOM 2894 C CB . LYS A 1 360 ? 50.584 112.627 37.282 1.00 21.32 ? 360 LYS A CB 1 ATOM 2895 C CG . LYS A 1 360 ? 51.296 113.981 36.889 1.00 20.68 ? 360 LYS A CG 1 ATOM 2896 C CD . LYS A 1 360 ? 50.295 115.154 36.762 1.00 23.87 ? 360 LYS A CD 1 ATOM 2897 C CE . LYS A 1 360 ? 50.884 116.370 36.028 1.00 23.90 ? 360 LYS A CE 1 ATOM 2898 N NZ . LYS A 1 360 ? 49.914 117.554 35.966 1.00 23.07 ? 360 LYS A NZ 1 ATOM 2899 N N . LEU A 1 361 ? 48.192 111.218 38.827 1.00 18.69 ? 361 LEU A N 1 ATOM 2900 C CA . LEU A 1 361 ? 47.343 110.056 39.041 1.00 19.06 ? 361 LEU A CA 1 ATOM 2901 C C . LEU A 1 361 ? 46.770 109.586 37.716 1.00 18.78 ? 361 LEU A C 1 ATOM 2902 O O . LEU A 1 361 ? 46.121 110.357 37.016 1.00 19.32 ? 361 LEU A O 1 ATOM 2903 C CB . LEU A 1 361 ? 46.147 110.377 39.970 1.00 19.22 ? 361 LEU A CB 1 ATOM 2904 C CG . LEU A 1 361 ? 45.185 109.188 40.178 1.00 19.05 ? 361 LEU A CG 1 ATOM 2905 C CD1 . LEU A 1 361 ? 45.872 108.067 40.996 1.00 21.60 ? 361 LEU A CD1 1 ATOM 2906 C CD2 . LEU A 1 361 ? 43.860 109.622 40.784 1.00 19.99 ? 361 LEU A CD2 1 ATOM 2907 N N . VAL A 1 362 ? 46.968 108.312 37.407 1.00 18.77 ? 362 VAL A N 1 ATOM 2908 C CA . VAL A 1 362 ? 46.349 107.700 36.242 1.00 18.74 ? 362 VAL A CA 1 ATOM 2909 C C . VAL A 1 362 ? 45.374 106.634 36.790 1.00 19.00 ? 362 VAL A C 1 ATOM 2910 O O . VAL A 1 362 ? 45.736 105.799 37.640 1.00 20.09 ? 362 VAL A O 1 ATOM 2911 C CB . VAL A 1 362 ? 47.386 107.053 35.251 1.00 19.45 ? 362 VAL A CB 1 ATOM 2912 C CG1 . VAL A 1 362 ? 46.651 106.331 34.086 1.00 17.18 ? 362 VAL A CG1 1 ATOM 2913 C CG2 . VAL A 1 362 ? 48.371 108.093 34.696 1.00 16.59 ? 362 VAL A CG2 1 ATOM 2914 N N . ILE A 1 363 ? 44.140 106.681 36.321 1.00 18.91 ? 363 ILE A N 1 ATOM 2915 C CA . ILE A 1 363 ? 43.125 105.713 36.750 1.00 19.44 ? 363 ILE A CA 1 ATOM 2916 C C . ILE A 1 363 ? 42.785 104.735 35.638 1.00 20.13 ? 363 ILE A C 1 ATOM 2917 O O . ILE A 1 363 ? 42.758 105.111 34.456 1.00 19.48 ? 363 ILE A O 1 ATOM 2918 C CB . ILE A 1 363 ? 41.787 106.417 37.185 1.00 20.44 ? 363 ILE A CB 1 ATOM 2919 C CG1 . ILE A 1 363 ? 41.297 107.410 36.100 1.00 19.86 ? 363 ILE A CG1 1 ATOM 2920 C CG2 . ILE A 1 363 ? 41.996 107.063 38.566 1.00 18.60 ? 363 ILE A CG2 1 ATOM 2921 C CD1 . ILE A 1 363 ? 39.737 107.667 36.080 1.00 19.52 ? 363 ILE A CD1 1 ATOM 2922 N N . ILE A 1 364 ? 42.555 103.475 36.017 1.00 20.35 ? 364 ILE A N 1 ATOM 2923 C CA . ILE A 1 364 ? 42.055 102.494 35.081 1.00 20.53 ? 364 ILE A CA 1 ATOM 2924 C C . ILE A 1 364 ? 40.545 102.737 34.835 1.00 21.91 ? 364 ILE A C 1 ATOM 2925 O O . ILE A 1 364 ? 39.790 103.136 35.765 1.00 21.30 ? 364 ILE A O 1 ATOM 2926 C CB . ILE A 1 364 ? 42.318 101.069 35.557 1.00 20.05 ? 364 ILE A CB 1 ATOM 2927 C CG1 . ILE A 1 364 ? 42.315 100.118 34.346 1.00 20.46 ? 364 ILE A CG1 1 ATOM 2928 C CG2 . ILE A 1 364 ? 41.246 100.637 36.591 1.00 20.83 ? 364 ILE A CG2 1 ATOM 2929 C CD1 . ILE A 1 364 ? 42.882 98.745 34.628 1.00 17.70 ? 364 ILE A CD1 1 ATOM 2930 N N . VAL A 1 365 ? 40.135 102.518 33.582 1.00 22.11 ? 365 VAL A N 1 ATOM 2931 C CA . VAL A 1 365 ? 38.750 102.585 33.158 1.00 23.36 ? 365 VAL A CA 1 ATOM 2932 C C . VAL A 1 365 ? 38.597 101.422 32.182 1.00 23.90 ? 365 VAL A C 1 ATOM 2933 O O . VAL A 1 365 ? 39.393 101.244 31.248 1.00 23.89 ? 365 VAL A O 1 ATOM 2934 C CB . VAL A 1 365 ? 38.361 103.966 32.518 1.00 23.44 ? 365 VAL A CB 1 ATOM 2935 C CG1 . VAL A 1 365 ? 36.883 104.046 32.269 1.00 24.40 ? 365 VAL A CG1 1 ATOM 2936 C CG2 . VAL A 1 365 ? 38.703 105.104 33.462 1.00 23.38 ? 365 VAL A CG2 1 ATOM 2937 N N . ASP A 1 366 ? 37.613 100.580 32.464 1.00 23.29 ? 366 ASP A N 1 ATOM 2938 C CA . ASP A 1 366 ? 37.317 99.445 31.628 1.00 22.89 ? 366 ASP A CA 1 ATOM 2939 C C . ASP A 1 366 ? 36.167 99.871 30.710 1.00 22.51 ? 366 ASP A C 1 ATOM 2940 O O . ASP A 1 366 ? 35.452 100.787 31.037 1.00 21.60 ? 366 ASP A O 1 ATOM 2941 C CB . ASP A 1 366 ? 36.895 98.279 32.507 1.00 22.76 ? 366 ASP A CB 1 ATOM 2942 C CG . ASP A 1 366 ? 37.984 97.815 33.423 1.00 23.75 ? 366 ASP A CG 1 ATOM 2943 O OD1 . ASP A 1 366 ? 39.131 97.501 32.965 1.00 20.29 ? 366 ASP A OD1 1 ATOM 2944 O OD2 . ASP A 1 366 ? 37.652 97.730 34.630 1.00 27.15 ? 366 ASP A OD2 1 ATOM 2945 N N . PRO A 1 367 ? 36.030 99.243 29.535 1.00 23.05 ? 367 PRO A N 1 ATOM 2946 C CA . PRO A 1 367 ? 34.884 99.587 28.689 1.00 23.26 ? 367 PRO A CA 1 ATOM 2947 C C . PRO A 1 367 ? 33.531 99.070 29.214 1.00 24.38 ? 367 PRO A C 1 ATOM 2948 O O . PRO A 1 367 ? 32.496 99.720 29.011 1.00 24.60 ? 367 PRO A O 1 ATOM 2949 C CB . PRO A 1 367 ? 35.213 98.919 27.351 1.00 23.39 ? 367 PRO A CB 1 ATOM 2950 C CG . PRO A 1 367 ? 36.191 97.816 27.681 1.00 22.66 ? 367 PRO A CG 1 ATOM 2951 C CD . PRO A 1 367 ? 36.926 98.238 28.921 1.00 21.85 ? 367 PRO A CD 1 ATOM 2952 N N . ALA A 1 368 ? 33.523 97.904 29.849 1.00 25.11 ? 368 ALA A N 1 ATOM 2953 C CA . ALA A 1 368 ? 32.252 97.237 30.124 1.00 25.52 ? 368 ALA A CA 1 ATOM 2954 C C . ALA A 1 368 ? 31.559 97.873 31.333 1.00 25.72 ? 368 ALA A C 1 ATOM 2955 O O . ALA A 1 368 ? 32.188 98.089 32.373 1.00 25.77 ? 368 ALA A O 1 ATOM 2956 C CB . ALA A 1 368 ? 32.446 95.766 30.316 1.00 25.34 ? 368 ALA A CB 1 ATOM 2957 N N . ILE A 1 369 ? 30.278 98.184 31.150 1.00 24.90 ? 369 ILE A N 1 ATOM 2958 C CA . ILE A 1 369 ? 29.439 98.889 32.126 1.00 25.38 ? 369 ILE A CA 1 ATOM 2959 C C . ILE A 1 369 ? 28.389 97.939 32.752 1.00 25.31 ? 369 ILE A C 1 ATOM 2960 O O . ILE A 1 369 ? 27.596 97.318 32.049 1.00 25.88 ? 369 ILE A O 1 ATOM 2961 C CB . ILE A 1 369 ? 28.735 100.157 31.476 1.00 24.81 ? 369 ILE A CB 1 ATOM 2962 C CG1 . ILE A 1 369 ? 29.769 101.123 30.843 1.00 24.93 ? 369 ILE A CG1 1 ATOM 2963 C CG2 . ILE A 1 369 ? 27.818 100.881 32.481 1.00 26.42 ? 369 ILE A CG2 1 ATOM 2964 C CD1 . ILE A 1 369 ? 30.769 101.801 31.810 1.00 24.43 ? 369 ILE A CD1 1 ATOM 2965 N N . SER A 1 370 ? 28.421 97.820 34.077 1.00 26.05 ? 370 SER A N 1 ATOM 2966 C CA . SER A 1 370 ? 27.419 97.099 34.848 1.00 26.33 ? 370 SER A CA 1 ATOM 2967 C C . SER A 1 370 ? 26.009 97.517 34.432 1.00 27.67 ? 370 SER A C 1 ATOM 2968 O O . SER A 1 370 ? 25.691 98.714 34.414 1.00 26.82 ? 370 SER A O 1 ATOM 2969 C CB . SER A 1 370 ? 27.586 97.432 36.328 1.00 26.15 ? 370 SER A CB 1 ATOM 2970 O OG . SER A 1 370 ? 26.643 96.707 37.111 1.00 25.24 ? 370 SER A OG 1 ATOM 2971 N N . ASN A 1 371 ? 25.169 96.532 34.101 1.00 29.69 ? 371 ASN A N 1 ATOM 2972 C CA . ASN A 1 371 ? 23.738 96.791 33.789 1.00 31.40 ? 371 ASN A CA 1 ATOM 2973 C C . ASN A 1 371 ? 22.846 96.648 35.030 1.00 33.50 ? 371 ASN A C 1 ATOM 2974 O O . ASN A 1 371 ? 21.612 96.513 34.919 1.00 33.53 ? 371 ASN A O 1 ATOM 2975 C CB . ASN A 1 371 ? 23.238 95.872 32.667 1.00 30.15 ? 371 ASN A CB 1 ATOM 2976 C CG . ASN A 1 371 ? 23.206 94.402 33.063 1.00 29.70 ? 371 ASN A CG 1 ATOM 2977 O OD1 . ASN A 1 371 ? 23.719 94.001 34.113 1.00 26.97 ? 371 ASN A OD1 1 ATOM 2978 N ND2 . ASN A 1 371 ? 22.590 93.579 32.206 1.00 27.69 ? 371 ASN A ND2 1 ATOM 2979 N N . ASN A 1 372 ? 23.483 96.646 36.201 1.00 34.97 ? 372 ASN A N 1 ATOM 2980 C CA . ASN A 1 372 ? 22.773 96.502 37.458 1.00 37.34 ? 372 ASN A CA 1 ATOM 2981 C C . ASN A 1 372 ? 22.349 97.865 38.003 1.00 37.77 ? 372 ASN A C 1 ATOM 2982 O O . ASN A 1 372 ? 23.106 98.545 38.683 1.00 37.47 ? 372 ASN A O 1 ATOM 2983 C CB . ASN A 1 372 ? 23.625 95.717 38.463 1.00 38.13 ? 372 ASN A CB 1 ATOM 2984 C CG . ASN A 1 372 ? 22.772 94.991 39.512 1.00 42.00 ? 372 ASN A CG 1 ATOM 2985 O OD1 . ASN A 1 372 ? 22.118 95.624 40.356 1.00 43.20 ? 372 ASN A OD1 1 ATOM 2986 N ND2 . ASN A 1 372 ? 22.787 93.655 39.466 1.00 44.44 ? 372 ASN A ND2 1 ATOM 2987 N N . SER A 1 373 ? 21.132 98.262 37.657 1.00 38.71 ? 373 SER A N 1 ATOM 2988 C CA . SER A 1 373 ? 20.585 99.553 38.043 1.00 40.26 ? 373 SER A CA 1 ATOM 2989 C C . SER A 1 373 ? 19.080 99.447 38.276 1.00 41.91 ? 373 SER A C 1 ATOM 2990 O O . SER A 1 373 ? 18.350 98.901 37.453 1.00 41.43 ? 373 SER A O 1 ATOM 2991 C CB . SER A 1 373 ? 20.843 100.601 36.958 1.00 39.67 ? 373 SER A CB 1 ATOM 2992 O OG . SER A 1 373 ? 20.561 101.900 37.435 1.00 38.78 ? 373 SER A OG 1 ATOM 2993 N N . SER A 1 374 ? 18.641 99.990 39.401 1.00 44.21 ? 374 SER A N 1 ATOM 2994 C CA . SER A 1 374 ? 17.221 100.080 39.753 1.00 46.25 ? 374 SER A CA 1 ATOM 2995 C C . SER A 1 374 ? 16.971 101.501 40.205 1.00 47.39 ? 374 SER A C 1 ATOM 2996 O O . SER A 1 374 ? 17.930 102.244 40.471 1.00 47.85 ? 374 SER A O 1 ATOM 2997 C CB . SER A 1 374 ? 16.889 99.096 40.888 1.00 46.29 ? 374 SER A CB 1 ATOM 2998 O OG . SER A 1 374 ? 17.846 99.173 41.943 1.00 46.51 ? 374 SER A OG 1 ATOM 2999 N N . SER A 1 375 ? 15.698 101.886 40.305 1.00 48.69 ? 375 SER A N 1 ATOM 3000 C CA . SER A 1 375 ? 15.322 103.223 40.813 1.00 49.53 ? 375 SER A CA 1 ATOM 3001 C C . SER A 1 375 ? 15.722 103.396 42.274 1.00 49.51 ? 375 SER A C 1 ATOM 3002 O O . SER A 1 375 ? 16.103 104.496 42.695 1.00 49.73 ? 375 SER A O 1 ATOM 3003 C CB . SER A 1 375 ? 13.821 103.457 40.644 1.00 50.26 ? 375 SER A CB 1 ATOM 3004 O OG . SER A 1 375 ? 13.398 102.982 39.367 1.00 52.38 ? 375 SER A OG 1 ATOM 3005 N N . SER A 1 376 ? 15.649 102.298 43.030 1.00 49.41 ? 376 SER A N 1 ATOM 3006 C CA . SER A 1 376 ? 16.093 102.266 44.419 1.00 49.40 ? 376 SER A CA 1 ATOM 3007 C C . SER A 1 376 ? 17.576 102.585 44.465 1.00 48.72 ? 376 SER A C 1 ATOM 3008 O O . SER A 1 376 ? 17.960 103.566 45.088 1.00 49.01 ? 376 SER A O 1 ATOM 3009 C CB . SER A 1 376 ? 15.827 100.897 45.081 1.00 49.70 ? 376 SER A CB 1 ATOM 3010 O OG . SER A 1 376 ? 14.780 100.172 44.439 1.00 51.17 ? 376 SER A OG 1 ATOM 3011 N N . LYS A 1 377 ? 18.393 101.765 43.784 1.00 47.82 ? 377 LYS A N 1 ATOM 3012 C CA . LYS A 1 377 ? 19.862 101.935 43.744 1.00 46.66 ? 377 LYS A CA 1 ATOM 3013 C C . LYS A 1 377 ? 20.356 102.216 42.296 1.00 44.58 ? 377 LYS A C 1 ATOM 3014 O O . LYS A 1 377 ? 20.608 101.286 41.516 1.00 43.76 ? 377 LYS A O 1 ATOM 3015 C CB . LYS A 1 377 ? 20.595 100.733 44.375 1.00 47.49 ? 377 LYS A CB 1 ATOM 3016 C CG . LYS A 1 377 ? 19.845 100.032 45.534 1.00 50.29 ? 377 LYS A CG 1 ATOM 3017 C CD . LYS A 1 377 ? 20.780 99.574 46.676 1.00 55.06 ? 377 LYS A CD 1 ATOM 3018 C CE . LYS A 1 377 ? 21.887 98.596 46.234 1.00 57.77 ? 377 LYS A CE 1 ATOM 3019 N NZ . LYS A 1 377 ? 21.375 97.332 45.595 1.00 59.16 ? 377 LYS A NZ 1 ATOM 3020 N N . PRO A 1 378 ? 20.448 103.509 41.927 1.00 42.48 ? 378 PRO A N 1 ATOM 3021 C CA . PRO A 1 378 ? 20.815 103.948 40.579 1.00 40.96 ? 378 PRO A CA 1 ATOM 3022 C C . PRO A 1 378 ? 22.317 103.770 40.287 1.00 39.21 ? 378 PRO A C 1 ATOM 3023 O O . PRO A 1 378 ? 23.147 103.984 41.182 1.00 39.21 ? 378 PRO A O 1 ATOM 3024 C CB . PRO A 1 378 ? 20.456 105.448 40.585 1.00 41.36 ? 378 PRO A CB 1 ATOM 3025 C CG . PRO A 1 378 ? 19.698 105.683 41.861 1.00 42.11 ? 378 PRO A CG 1 ATOM 3026 C CD . PRO A 1 378 ? 20.192 104.656 42.811 1.00 42.52 ? 378 PRO A CD 1 ATOM 3027 N N . TYR A 1 379 ? 22.643 103.343 39.064 1.00 36.56 ? 379 TYR A N 1 ATOM 3028 C CA . TYR A 1 379 ? 24.030 103.358 38.562 1.00 34.00 ? 379 TYR A CA 1 ATOM 3029 C C . TYR A 1 379 ? 24.092 104.264 37.330 1.00 32.38 ? 379 TYR A C 1 ATOM 3030 O O . TYR A 1 379 ? 23.715 103.867 36.209 1.00 32.70 ? 379 TYR A O 1 ATOM 3031 C CB . TYR A 1 379 ? 24.561 101.940 38.283 1.00 32.88 ? 379 TYR A CB 1 ATOM 3032 C CG . TYR A 1 379 ? 25.997 101.905 37.785 1.00 32.78 ? 379 TYR A CG 1 ATOM 3033 C CD1 . TYR A 1 379 ? 27.039 102.504 38.520 1.00 30.97 ? 379 TYR A CD1 1 ATOM 3034 C CD2 . TYR A 1 379 ? 26.320 101.264 36.576 1.00 31.38 ? 379 TYR A CD2 1 ATOM 3035 C CE1 . TYR A 1 379 ? 28.353 102.478 38.047 1.00 31.47 ? 379 TYR A CE1 1 ATOM 3036 C CE2 . TYR A 1 379 ? 27.624 101.216 36.102 1.00 30.09 ? 379 TYR A CE2 1 ATOM 3037 C CZ . TYR A 1 379 ? 28.640 101.822 36.834 1.00 31.61 ? 379 TYR A CZ 1 ATOM 3038 O OH . TYR A 1 379 ? 29.928 101.778 36.351 1.00 29.92 ? 379 TYR A OH 1 ATOM 3039 N N . GLY A 1 380 ? 24.544 105.492 37.568 1.00 30.45 ? 380 GLY A N 1 ATOM 3040 C CA . GLY A 1 380 ? 24.478 106.570 36.595 1.00 28.49 ? 380 GLY A CA 1 ATOM 3041 C C . GLY A 1 380 ? 25.056 106.298 35.219 1.00 27.50 ? 380 GLY A C 1 ATOM 3042 O O . GLY A 1 380 ? 24.399 106.610 34.244 1.00 27.67 ? 380 GLY A O 1 ATOM 3043 N N . PRO A 1 381 ? 26.308 105.749 35.122 1.00 27.24 ? 381 PRO A N 1 ATOM 3044 C CA . PRO A 1 381 ? 26.869 105.475 33.773 1.00 26.78 ? 381 PRO A CA 1 ATOM 3045 C C . PRO A 1 381 ? 25.991 104.534 32.938 1.00 26.36 ? 381 PRO A C 1 ATOM 3046 O O . PRO A 1 381 ? 25.823 104.755 31.749 1.00 25.90 ? 381 PRO A O 1 ATOM 3047 C CB . PRO A 1 381 ? 28.235 104.834 34.077 1.00 25.84 ? 381 PRO A CB 1 ATOM 3048 C CG . PRO A 1 381 ? 28.587 105.311 35.433 1.00 26.61 ? 381 PRO A CG 1 ATOM 3049 C CD . PRO A 1 381 ? 27.274 105.381 36.181 1.00 26.10 ? 381 PRO A CD 1 ATOM 3050 N N . TYR A 1 382 ? 25.400 103.516 33.560 1.00 27.22 ? 382 TYR A N 1 ATOM 3051 C CA . TYR A 1 382 ? 24.452 102.684 32.835 1.00 27.51 ? 382 TYR A CA 1 ATOM 3052 C C . TYR A 1 382 ? 23.141 103.393 32.476 1.00 28.46 ? 382 TYR A C 1 ATOM 3053 O O . TYR A 1 382 ? 22.641 103.232 31.355 1.00 28.46 ? 382 TYR A O 1 ATOM 3054 C CB . TYR A 1 382 ? 24.182 101.398 33.586 1.00 28.20 ? 382 TYR A CB 1 ATOM 3055 C CG . TYR A 1 382 ? 23.193 100.514 32.876 1.00 28.71 ? 382 TYR A CG 1 ATOM 3056 C CD1 . TYR A 1 382 ? 23.552 99.807 31.727 1.00 27.58 ? 382 TYR A CD1 1 ATOM 3057 C CD2 . TYR A 1 382 ? 21.881 100.406 33.343 1.00 30.03 ? 382 TYR A CD2 1 ATOM 3058 C CE1 . TYR A 1 382 ? 22.629 99.010 31.075 1.00 29.69 ? 382 TYR A CE1 1 ATOM 3059 C CE2 . TYR A 1 382 ? 20.952 99.599 32.710 1.00 29.85 ? 382 TYR A CE2 1 ATOM 3060 C CZ . TYR A 1 382 ? 21.329 98.900 31.586 1.00 29.72 ? 382 TYR A CZ 1 ATOM 3061 O OH . TYR A 1 382 ? 20.387 98.107 30.967 1.00 30.36 ? 382 TYR A OH 1 ATOM 3062 N N . ASP A 1 383 ? 22.579 104.166 33.414 1.00 29.08 ? 383 ASP A N 1 ATOM 3063 C CA . ASP A 1 383 ? 21.328 104.883 33.126 1.00 30.28 ? 383 ASP A CA 1 ATOM 3064 C C . ASP A 1 383 ? 21.521 105.898 32.010 1.00 29.44 ? 383 ASP A C 1 ATOM 3065 O O . ASP A 1 383 ? 20.737 105.933 31.092 1.00 29.39 ? 383 ASP A O 1 ATOM 3066 C CB . ASP A 1 383 ? 20.748 105.572 34.379 1.00 30.77 ? 383 ASP A CB 1 ATOM 3067 C CG . ASP A 1 383 ? 20.391 104.583 35.488 1.00 34.07 ? 383 ASP A CG 1 ATOM 3068 O OD1 . ASP A 1 383 ? 20.123 103.391 35.200 1.00 36.43 ? 383 ASP A OD1 1 ATOM 3069 O OD2 . ASP A 1 383 ? 20.393 105.008 36.666 1.00 39.28 ? 383 ASP A OD2 1 ATOM 3070 N N . ARG A 1 384 ? 22.580 106.703 32.076 1.00 29.13 ? 384 ARG A N 1 ATOM 3071 C CA . ARG A 1 384 ? 22.852 107.680 31.033 1.00 29.06 ? 384 ARG A CA 1 ATOM 3072 C C . ARG A 1 384 ? 23.197 107.018 29.694 1.00 29.69 ? 384 ARG A C 1 ATOM 3073 O O . ARG A 1 384 ? 22.806 107.512 28.611 1.00 29.35 ? 384 ARG A O 1 ATOM 3074 C CB . ARG A 1 384 ? 23.959 108.642 31.474 1.00 29.23 ? 384 ARG A CB 1 ATOM 3075 C CG . ARG A 1 384 ? 23.509 109.611 32.570 1.00 29.45 ? 384 ARG A CG 1 ATOM 3076 C CD . ARG A 1 384 ? 24.627 110.585 33.013 1.00 29.80 ? 384 ARG A CD 1 ATOM 3077 N NE . ARG A 1 384 ? 25.719 109.891 33.688 1.00 31.42 ? 384 ARG A NE 1 ATOM 3078 C CZ . ARG A 1 384 ? 25.757 109.622 34.997 1.00 31.37 ? 384 ARG A CZ 1 ATOM 3079 N NH1 . ARG A 1 384 ? 24.779 110.010 35.806 1.00 28.30 ? 384 ARG A NH1 1 ATOM 3080 N NH2 . ARG A 1 384 ? 26.791 108.975 35.508 1.00 28.92 ? 384 ARG A NH2 1 ATOM 3081 N N . GLY A 1 385 ? 23.919 105.897 29.762 1.00 29.66 ? 385 GLY A N 1 ATOM 3082 C CA . GLY A 1 385 ? 24.241 105.129 28.559 1.00 30.13 ? 385 GLY A CA 1 ATOM 3083 C C . GLY A 1 385 ? 23.019 104.539 27.876 1.00 30.49 ? 385 GLY A C 1 ATOM 3084 O O . GLY A 1 385 ? 22.888 104.606 26.650 1.00 29.67 ? 385 GLY A O 1 ATOM 3085 N N . SER A 1 386 ? 22.119 103.961 28.666 1.00 31.08 ? 386 SER A N 1 ATOM 3086 C CA . SER A 1 386 ? 20.873 103.414 28.104 1.00 32.45 ? 386 SER A CA 1 ATOM 3087 C C . SER A 1 386 ? 19.942 104.500 27.557 1.00 33.30 ? 386 SER A C 1 ATOM 3088 O O . SER A 1 386 ? 19.222 104.256 26.593 1.00 33.49 ? 386 SER A O 1 ATOM 3089 C CB . SER A 1 386 ? 20.146 102.548 29.122 1.00 32.02 ? 386 SER A CB 1 ATOM 3090 O OG . SER A 1 386 ? 21.019 101.540 29.585 1.00 33.29 ? 386 SER A OG 1 ATOM 3091 N N . ASP A 1 387 ? 19.979 105.697 28.148 1.00 34.80 ? 387 ASP A N 1 ATOM 3092 C CA . ASP A 1 387 ? 19.204 106.833 27.631 1.00 36.71 ? 387 ASP A CA 1 ATOM 3093 C C . ASP A 1 387 ? 19.696 107.217 26.244 1.00 36.66 ? 387 ASP A C 1 ATOM 3094 O O . ASP A 1 387 ? 18.904 107.596 25.372 1.00 36.11 ? 387 ASP A O 1 ATOM 3095 C CB . ASP A 1 387 ? 19.324 108.056 28.539 1.00 37.24 ? 387 ASP A CB 1 ATOM 3096 C CG . ASP A 1 387 ? 18.630 107.868 29.857 1.00 42.87 ? 387 ASP A CG 1 ATOM 3097 O OD1 . ASP A 1 387 ? 17.707 107.009 29.944 1.00 47.13 ? 387 ASP A OD1 1 ATOM 3098 O OD2 . ASP A 1 387 ? 19.019 108.578 30.822 1.00 48.54 ? 387 ASP A OD2 1 ATOM 3099 N N . MET A 1 388 ? 21.013 107.126 26.057 1.00 36.23 ? 388 MET A N 1 ATOM 3100 C CA . MET A 1 388 ? 21.630 107.499 24.788 1.00 36.62 ? 388 MET A CA 1 ATOM 3101 C C . MET A 1 388 ? 21.612 106.386 23.713 1.00 35.24 ? 388 MET A C 1 ATOM 3102 O O . MET A 1 388 ? 21.868 106.646 22.543 1.00 35.53 ? 388 MET A O 1 ATOM 3103 C CB . MET A 1 388 ? 23.027 108.062 25.043 1.00 36.29 ? 388 MET A CB 1 ATOM 3104 C CG . MET A 1 388 ? 22.956 109.340 25.877 1.00 37.68 ? 388 MET A CG 1 ATOM 3105 S SD . MET A 1 388 ? 24.489 110.285 26.014 1.00 39.40 ? 388 MET A SD 1 ATOM 3106 C CE . MET A 1 388 ? 24.687 110.881 24.339 1.00 35.27 ? 388 MET A CE 1 ATOM 3107 N N . LYS A 1 389 ? 21.263 105.166 24.111 1.00 33.37 ? 389 LYS A N 1 ATOM 3108 C CA . LYS A 1 389 ? 21.214 104.038 23.195 1.00 32.45 ? 389 LYS A CA 1 ATOM 3109 C C . LYS A 1 389 ? 22.597 103.727 22.539 1.00 30.43 ? 389 LYS A C 1 ATOM 3110 O O . LYS A 1 389 ? 22.697 103.374 21.358 1.00 28.92 ? 389 LYS A O 1 ATOM 3111 C CB . LYS A 1 389 ? 20.050 104.205 22.195 1.00 32.95 ? 389 LYS A CB 1 ATOM 3112 C CG . LYS A 1 389 ? 18.667 103.951 22.890 1.00 33.93 ? 389 LYS A CG 1 ATOM 3113 C CD . LYS A 1 389 ? 17.471 104.500 22.120 1.00 35.17 ? 389 LYS A CD 1 ATOM 3114 C CE . LYS A 1 389 ? 16.245 104.650 23.064 1.00 39.21 ? 389 LYS A CE 1 ATOM 3115 N NZ . LYS A 1 389 ? 15.830 103.288 23.615 1.00 42.58 ? 389 LYS A NZ 1 ATOM 3116 N N . ILE A 1 390 ? 23.648 103.837 23.350 1.00 28.56 ? 390 ILE A N 1 ATOM 3117 C CA . ILE A 1 390 ? 25.019 103.738 22.838 1.00 27.07 ? 390 ILE A CA 1 ATOM 3118 C C . ILE A 1 390 ? 25.760 102.401 23.068 1.00 26.53 ? 390 ILE A C 1 ATOM 3119 O O . ILE A 1 390 ? 27.032 102.360 22.976 1.00 25.65 ? 390 ILE A O 1 ATOM 3120 C CB . ILE A 1 390 ? 25.887 104.964 23.268 1.00 26.37 ? 390 ILE A CB 1 ATOM 3121 C CG1 . ILE A 1 390 ? 25.842 105.208 24.782 1.00 25.00 ? 390 ILE A CG1 1 ATOM 3122 C CG2 . ILE A 1 390 ? 25.448 106.223 22.478 1.00 25.85 ? 390 ILE A CG2 1 ATOM 3123 C CD1 . ILE A 1 390 ? 26.548 104.149 25.696 1.00 20.11 ? 390 ILE A CD1 1 ATOM 3124 N N . TRP A 1 391 ? 25.001 101.327 23.337 1.00 24.59 ? 391 TRP A N 1 ATOM 3125 C CA . TRP A 1 391 ? 25.596 100.003 23.611 1.00 24.20 ? 391 TRP A CA 1 ATOM 3126 C C . TRP A 1 391 ? 25.771 99.218 22.322 1.00 23.87 ? 391 TRP A C 1 ATOM 3127 O O . TRP A 1 391 ? 25.107 99.506 21.340 1.00 23.37 ? 391 TRP A O 1 ATOM 3128 C CB . TRP A 1 391 ? 24.778 99.167 24.618 1.00 24.32 ? 391 TRP A CB 1 ATOM 3129 C CG . TRP A 1 391 ? 24.341 99.897 25.844 1.00 25.26 ? 391 TRP A CG 1 ATOM 3130 C CD1 . TRP A 1 391 ? 23.048 100.085 26.268 1.00 25.08 ? 391 TRP A CD1 1 ATOM 3131 C CD2 . TRP A 1 391 ? 25.179 100.515 26.833 1.00 26.19 ? 391 TRP A CD2 1 ATOM 3132 N NE1 . TRP A 1 391 ? 23.035 100.788 27.454 1.00 25.48 ? 391 TRP A NE1 1 ATOM 3133 C CE2 . TRP A 1 391 ? 24.324 101.078 27.815 1.00 26.50 ? 391 TRP A CE2 1 ATOM 3134 C CE3 . TRP A 1 391 ? 26.574 100.658 26.983 1.00 26.89 ? 391 TRP A CE3 1 ATOM 3135 C CZ2 . TRP A 1 391 ? 24.815 101.760 28.932 1.00 26.95 ? 391 TRP A CZ2 1 ATOM 3136 C CZ3 . TRP A 1 391 ? 27.055 101.346 28.075 1.00 25.89 ? 391 TRP A CZ3 1 ATOM 3137 C CH2 . TRP A 1 391 ? 26.182 101.895 29.035 1.00 26.56 ? 391 TRP A CH2 1 ATOM 3138 N N . VAL A 1 392 ? 26.696 98.255 22.326 1.00 23.29 ? 392 VAL A N 1 ATOM 3139 C CA . VAL A 1 392 ? 26.789 97.250 21.279 1.00 23.17 ? 392 VAL A CA 1 ATOM 3140 C C . VAL A 1 392 ? 25.518 96.362 21.402 1.00 24.19 ? 392 VAL A C 1 ATOM 3141 O O . VAL A 1 392 ? 25.186 95.923 22.509 1.00 24.54 ? 392 VAL A O 1 ATOM 3142 C CB . VAL A 1 392 ? 28.022 96.312 21.512 1.00 23.40 ? 392 VAL A CB 1 ATOM 3143 C CG1 . VAL A 1 392 ? 27.995 95.139 20.529 1.00 22.26 ? 392 VAL A CG1 1 ATOM 3144 C CG2 . VAL A 1 392 ? 29.358 97.093 21.501 1.00 20.76 ? 392 VAL A CG2 1 ATOM 3145 N N . ASN A 1 393 ? 24.814 96.122 20.292 1.00 24.50 ? 393 ASN A N 1 ATOM 3146 C CA . ASN A 1 393 ? 23.585 95.299 20.290 1.00 24.90 ? 393 ASN A CA 1 ATOM 3147 C C . ASN A 1 393 ? 23.837 93.867 19.820 1.00 25.11 ? 393 ASN A C 1 ATOM 3148 O O . ASN A 1 393 ? 24.757 93.618 19.050 1.00 24.75 ? 393 ASN A O 1 ATOM 3149 C CB . ASN A 1 393 ? 22.549 95.930 19.352 1.00 25.07 ? 393 ASN A CB 1 ATOM 3150 C CG . ASN A 1 393 ? 22.105 97.315 19.793 1.00 24.97 ? 393 ASN A CG 1 ATOM 3151 O OD1 . ASN A 1 393 ? 22.291 97.709 20.945 1.00 25.97 ? 393 ASN A OD1 1 ATOM 3152 N ND2 . ASN A 1 393 ? 21.517 98.061 18.857 1.00 27.65 ? 393 ASN A ND2 1 ATOM 3153 N N . SER A 1 394 ? 22.997 92.927 20.241 1.00 25.98 ? 394 SER A N 1 ATOM 3154 C CA . SER A 1 394 ? 23.015 91.589 19.658 1.00 27.09 ? 394 SER A CA 1 ATOM 3155 C C . SER A 1 394 ? 22.552 91.631 18.215 1.00 26.68 ? 394 SER A C 1 ATOM 3156 O O . SER A 1 394 ? 22.200 92.691 17.725 1.00 26.10 ? 394 SER A O 1 ATOM 3157 C CB . SER A 1 394 ? 22.166 90.632 20.484 1.00 27.78 ? 394 SER A CB 1 ATOM 3158 O OG . SER A 1 394 ? 22.949 90.167 21.570 1.00 32.72 ? 394 SER A OG 1 ATOM 3159 N N . SER A 1 395 ? 22.573 90.490 17.527 1.00 27.54 ? 395 SER A N 1 ATOM 3160 C CA . SER A 1 395 ? 22.280 90.468 16.086 1.00 29.31 ? 395 SER A CA 1 ATOM 3161 C C . SER A 1 395 ? 20.897 91.006 15.679 1.00 30.43 ? 395 SER A C 1 ATOM 3162 O O . SER A 1 395 ? 20.724 91.394 14.522 1.00 30.87 ? 395 SER A O 1 ATOM 3163 C CB . SER A 1 395 ? 22.485 89.084 15.480 1.00 28.73 ? 395 SER A CB 1 ATOM 3164 O OG . SER A 1 395 ? 21.717 88.123 16.173 1.00 31.36 ? 395 SER A OG 1 ATOM 3165 N N . ASP A 1 396 ? 19.926 91.037 16.597 1.00 31.36 ? 396 ASP A N 1 ATOM 3166 C CA . ASP A 1 396 ? 18.611 91.589 16.245 1.00 32.70 ? 396 ASP A CA 1 ATOM 3167 C C . ASP A 1 396 ? 18.684 93.098 15.918 1.00 33.24 ? 396 ASP A C 1 ATOM 3168 O O . ASP A 1 396 ? 17.748 93.682 15.370 1.00 33.67 ? 396 ASP A O 1 ATOM 3169 C CB . ASP A 1 396 ? 17.512 91.222 17.274 1.00 33.17 ? 396 ASP A CB 1 ATOM 3170 C CG . ASP A 1 396 ? 17.730 91.846 18.671 1.00 34.97 ? 396 ASP A CG 1 ATOM 3171 O OD1 . ASP A 1 396 ? 18.682 92.644 18.887 1.00 35.55 ? 396 ASP A OD1 1 ATOM 3172 O OD2 . ASP A 1 396 ? 16.911 91.532 19.575 1.00 38.20 ? 396 ASP A OD2 1 ATOM 3173 N N . GLY A 1 397 ? 19.829 93.711 16.210 1.00 33.46 ? 397 GLY A N 1 ATOM 3174 C CA . GLY A 1 397 ? 20.034 95.127 15.970 1.00 32.67 ? 397 GLY A CA 1 ATOM 3175 C C . GLY A 1 397 ? 19.337 96.037 16.966 1.00 32.88 ? 397 GLY A C 1 ATOM 3176 O O . GLY A 1 397 ? 19.431 97.240 16.829 1.00 33.47 ? 397 GLY A O 1 ATOM 3177 N N . VAL A 1 398 ? 18.618 95.503 17.951 1.00 32.76 ? 398 VAL A N 1 ATOM 3178 C CA . VAL A 1 398 ? 17.921 96.399 18.920 1.00 32.29 ? 398 VAL A CA 1 ATOM 3179 C C . VAL A 1 398 ? 18.169 96.158 20.416 1.00 31.23 ? 398 VAL A C 1 ATOM 3180 O O . VAL A 1 398 ? 18.015 97.062 21.204 1.00 31.19 ? 398 VAL A O 1 ATOM 3181 C CB . VAL A 1 398 ? 16.366 96.569 18.649 1.00 33.03 ? 398 VAL A CB 1 ATOM 3182 C CG1 . VAL A 1 398 ? 16.109 97.249 17.296 1.00 33.41 ? 398 VAL A CG1 1 ATOM 3183 C CG2 . VAL A 1 398 ? 15.605 95.250 18.785 1.00 32.45 ? 398 VAL A CG2 1 ATOM 3184 N N . THR A 1 399 ? 18.540 94.943 20.798 1.00 30.32 ? 399 THR A N 1 ATOM 3185 C CA . THR A 1 399 ? 18.768 94.620 22.212 1.00 30.42 ? 399 THR A CA 1 ATOM 3186 C C . THR A 1 399 ? 20.277 94.661 22.533 1.00 29.59 ? 399 THR A C 1 ATOM 3187 O O . THR A 1 399 ? 21.057 93.971 21.868 1.00 28.89 ? 399 THR A O 1 ATOM 3188 C CB . THR A 1 399 ? 18.218 93.215 22.560 1.00 30.21 ? 399 THR A CB 1 ATOM 3189 O OG1 . THR A 1 399 ? 17.011 92.975 21.821 1.00 32.03 ? 399 THR A OG1 1 ATOM 3190 C CG2 . THR A 1 399 ? 17.939 93.086 24.053 1.00 31.58 ? 399 THR A CG2 1 ATOM 3191 N N . PRO A 1 400 ? 20.682 95.487 23.520 1.00 28.68 ? 400 PRO A N 1 ATOM 3192 C CA . PRO A 1 400 ? 22.067 95.503 23.989 1.00 28.03 ? 400 PRO A CA 1 ATOM 3193 C C . PRO A 1 400 ? 22.605 94.116 24.352 1.00 27.78 ? 400 PRO A C 1 ATOM 3194 O O . PRO A 1 400 ? 21.943 93.348 25.067 1.00 27.93 ? 400 PRO A O 1 ATOM 3195 C CB . PRO A 1 400 ? 22.024 96.440 25.208 1.00 28.02 ? 400 PRO A CB 1 ATOM 3196 C CG . PRO A 1 400 ? 20.942 97.414 24.857 1.00 28.48 ? 400 PRO A CG 1 ATOM 3197 C CD . PRO A 1 400 ? 19.867 96.520 24.196 1.00 28.69 ? 400 PRO A CD 1 ATOM 3198 N N . LEU A 1 401 ? 23.801 93.800 23.858 1.00 26.21 ? 401 LEU A N 1 ATOM 3199 C CA . LEU A 1 401 ? 24.465 92.549 24.199 1.00 25.11 ? 401 LEU A CA 1 ATOM 3200 C C . LEU A 1 401 ? 24.903 92.548 25.676 1.00 24.76 ? 401 LEU A C 1 ATOM 3201 O O . LEU A 1 401 ? 25.540 93.494 26.160 1.00 25.20 ? 401 LEU A O 1 ATOM 3202 C CB . LEU A 1 401 ? 25.636 92.290 23.245 1.00 23.96 ? 401 LEU A CB 1 ATOM 3203 C CG . LEU A 1 401 ? 26.369 90.948 23.320 1.00 25.53 ? 401 LEU A CG 1 ATOM 3204 C CD1 . LEU A 1 401 ? 27.131 90.665 22.014 1.00 26.59 ? 401 LEU A CD1 1 ATOM 3205 C CD2 . LEU A 1 401 ? 27.321 90.846 24.495 1.00 23.56 ? 401 LEU A CD2 1 ATOM 3206 N N . ILE A 1 402 ? 24.570 91.475 26.382 1.00 23.90 ? 402 ILE A N 1 ATOM 3207 C CA . ILE A 1 402 ? 25.024 91.289 27.753 1.00 24.50 ? 402 ILE A CA 1 ATOM 3208 C C . ILE A 1 402 ? 26.152 90.264 27.826 1.00 23.34 ? 402 ILE A C 1 ATOM 3209 O O . ILE A 1 402 ? 26.071 89.162 27.275 1.00 23.41 ? 402 ILE A O 1 ATOM 3210 C CB . ILE A 1 402 ? 23.877 90.807 28.721 1.00 25.79 ? 402 ILE A CB 1 ATOM 3211 C CG1 . ILE A 1 402 ? 22.561 91.596 28.519 1.00 27.76 ? 402 ILE A CG1 1 ATOM 3212 C CG2 . ILE A 1 402 ? 24.337 90.834 30.206 1.00 26.34 ? 402 ILE A CG2 1 ATOM 3213 C CD1 . ILE A 1 402 ? 22.649 93.005 28.925 1.00 31.60 ? 402 ILE A CD1 1 ATOM 3214 N N . GLY A 1 403 ? 27.207 90.641 28.534 1.00 22.91 ? 403 GLY A N 1 ATOM 3215 C CA . GLY A 1 403 ? 28.323 89.777 28.795 1.00 22.26 ? 403 GLY A CA 1 ATOM 3216 C C . GLY A 1 403 ? 28.639 89.895 30.270 1.00 22.62 ? 403 GLY A C 1 ATOM 3217 O O . GLY A 1 403 ? 27.770 90.220 31.072 1.00 22.11 ? 403 GLY A O 1 ATOM 3218 N N . GLU A 1 404 ? 29.876 89.618 30.630 1.00 22.02 ? 404 GLU A N 1 ATOM 3219 C CA . GLU A 1 404 ? 30.298 89.615 32.008 1.00 22.83 ? 404 GLU A CA 1 ATOM 3220 C C . GLU A 1 404 ? 31.782 90.009 32.074 1.00 22.91 ? 404 GLU A C 1 ATOM 3221 O O . GLU A 1 404 ? 32.612 89.388 31.389 1.00 22.15 ? 404 GLU A O 1 ATOM 3222 C CB . GLU A 1 404 ? 30.152 88.198 32.567 1.00 23.47 ? 404 GLU A CB 1 ATOM 3223 C CG . GLU A 1 404 ? 30.277 88.101 34.077 1.00 30.43 ? 404 GLU A CG 1 ATOM 3224 C CD . GLU A 1 404 ? 30.597 86.672 34.546 1.00 39.25 ? 404 GLU A CD 1 ATOM 3225 O OE1 . GLU A 1 404 ? 29.921 85.724 34.053 1.00 42.81 ? 404 GLU A OE1 1 ATOM 3226 O OE2 . GLU A 1 404 ? 31.517 86.508 35.400 1.00 40.40 ? 404 GLU A OE2 1 ATOM 3227 N N . VAL A 1 405 ? 32.103 91.020 32.887 1.00 22.17 ? 405 VAL A N 1 ATOM 3228 C CA . VAL A 1 405 ? 33.493 91.383 33.201 1.00 21.11 ? 405 VAL A CA 1 ATOM 3229 C C . VAL A 1 405 ? 33.589 91.611 34.734 1.00 20.97 ? 405 VAL A C 1 ATOM 3230 O O . VAL A 1 405 ? 32.862 90.950 35.486 1.00 19.81 ? 405 VAL A O 1 ATOM 3231 C CB . VAL A 1 405 ? 34.046 92.557 32.355 1.00 21.64 ? 405 VAL A CB 1 ATOM 3232 C CG1 . VAL A 1 405 ? 35.615 92.493 32.275 1.00 19.83 ? 405 VAL A CG1 1 ATOM 3233 C CG2 . VAL A 1 405 ? 33.518 92.533 30.937 1.00 21.53 ? 405 VAL A CG2 1 ATOM 3234 N N . TRP A 1 406 ? 34.448 92.524 35.195 1.00 20.51 ? 406 TRP A N 1 ATOM 3235 C CA . TRP A 1 406 ? 34.769 92.638 36.611 1.00 21.04 ? 406 TRP A CA 1 ATOM 3236 C C . TRP A 1 406 ? 33.567 92.881 37.546 1.00 22.92 ? 406 TRP A C 1 ATOM 3237 O O . TRP A 1 406 ? 33.525 92.285 38.618 1.00 23.18 ? 406 TRP A O 1 ATOM 3238 C CB . TRP A 1 406 ? 35.788 93.744 36.857 1.00 21.05 ? 406 TRP A CB 1 ATOM 3239 C CG . TRP A 1 406 ? 37.069 93.585 36.112 1.00 20.19 ? 406 TRP A CG 1 ATOM 3240 C CD1 . TRP A 1 406 ? 37.571 94.419 35.157 1.00 20.48 ? 406 TRP A CD1 1 ATOM 3241 C CD2 . TRP A 1 406 ? 38.030 92.542 36.294 1.00 21.15 ? 406 TRP A CD2 1 ATOM 3242 N NE1 . TRP A 1 406 ? 38.804 93.936 34.699 1.00 19.45 ? 406 TRP A NE1 1 ATOM 3243 C CE2 . TRP A 1 406 ? 39.102 92.790 35.392 1.00 21.25 ? 406 TRP A CE2 1 ATOM 3244 C CE3 . TRP A 1 406 ? 38.098 91.414 37.140 1.00 23.36 ? 406 TRP A CE3 1 ATOM 3245 C CZ2 . TRP A 1 406 ? 40.215 91.945 35.303 1.00 22.44 ? 406 TRP A CZ2 1 ATOM 3246 C CZ3 . TRP A 1 406 ? 39.220 90.566 37.040 1.00 21.90 ? 406 TRP A CZ3 1 ATOM 3247 C CH2 . TRP A 1 406 ? 40.263 90.853 36.130 1.00 21.55 ? 406 TRP A CH2 1 ATOM 3248 N N . PRO A 1 407 ? 32.635 93.782 37.163 1.00 23.51 ? 407 PRO A N 1 ATOM 3249 C CA . PRO A 1 407 ? 31.530 94.044 38.071 1.00 25.59 ? 407 PRO A CA 1 ATOM 3250 C C . PRO A 1 407 ? 30.425 93.003 38.104 1.00 26.73 ? 407 PRO A C 1 ATOM 3251 O O . PRO A 1 407 ? 29.601 93.065 38.999 1.00 27.91 ? 407 PRO A O 1 ATOM 3252 C CB . PRO A 1 407 ? 30.955 95.374 37.564 1.00 24.58 ? 407 PRO A CB 1 ATOM 3253 C CG . PRO A 1 407 ? 31.323 95.450 36.144 1.00 24.22 ? 407 PRO A CG 1 ATOM 3254 C CD . PRO A 1 407 ? 32.558 94.627 35.946 1.00 23.68 ? 407 PRO A CD 1 ATOM 3255 N N . GLY A 1 408 ? 30.430 92.037 37.195 1.00 27.28 ? 408 GLY A N 1 ATOM 3256 C CA . GLY A 1 408 ? 29.274 91.158 37.030 1.00 28.18 ? 408 GLY A CA 1 ATOM 3257 C C . GLY A 1 408 ? 28.750 91.325 35.616 1.00 28.90 ? 408 GLY A C 1 ATOM 3258 O O . GLY A 1 408 ? 29.527 91.663 34.713 1.00 29.34 ? 408 GLY A O 1 ATOM 3259 N N . GLN A 1 409 ? 27.453 91.104 35.403 1.00 28.88 ? 409 GLN A N 1 ATOM 3260 C CA . GLN A 1 409 ? 26.865 91.283 34.060 1.00 29.18 ? 409 GLN A CA 1 ATOM 3261 C C . GLN A 1 409 ? 26.965 92.730 33.564 1.00 28.22 ? 409 GLN A C 1 ATOM 3262 O O . GLN A 1 409 ? 26.787 93.686 34.330 1.00 27.36 ? 409 GLN A O 1 ATOM 3263 C CB . GLN A 1 409 ? 25.438 90.741 33.953 1.00 30.03 ? 409 GLN A CB 1 ATOM 3264 C CG . GLN A 1 409 ? 25.317 89.300 34.419 1.00 34.33 ? 409 GLN A CG 1 ATOM 3265 C CD . GLN A 1 409 ? 24.322 88.495 33.606 1.00 40.07 ? 409 GLN A CD 1 ATOM 3266 O OE1 . GLN A 1 409 ? 23.351 89.029 33.053 1.00 42.00 ? 409 GLN A OE1 1 ATOM 3267 N NE2 . GLN A 1 409 ? 24.556 87.190 33.532 1.00 42.75 ? 409 GLN A NE2 1 ATOM 3268 N N . THR A 1 410 ? 27.267 92.870 32.277 1.00 27.15 ? 410 THR A N 1 ATOM 3269 C CA . THR A 1 410 ? 27.635 94.172 31.706 1.00 25.82 ? 410 THR A CA 1 ATOM 3270 C C . THR A 1 410 ? 27.135 94.326 30.295 1.00 25.36 ? 410 THR A C 1 ATOM 3271 O O . THR A 1 410 ? 26.936 93.348 29.592 1.00 25.71 ? 410 THR A O 1 ATOM 3272 C CB . THR A 1 410 ? 29.185 94.387 31.617 1.00 25.41 ? 410 THR A CB 1 ATOM 3273 O OG1 . THR A 1 410 ? 29.754 93.379 30.771 1.00 25.24 ? 410 THR A OG1 1 ATOM 3274 C CG2 . THR A 1 410 ? 29.869 94.370 32.964 1.00 22.13 ? 410 THR A CG2 1 ATOM 3275 N N . VAL A 1 411 ? 26.972 95.579 29.886 1.00 24.71 ? 411 VAL A N 1 ATOM 3276 C CA . VAL A 1 411 ? 26.823 95.964 28.480 1.00 23.53 ? 411 VAL A CA 1 ATOM 3277 C C . VAL A 1 411 ? 28.140 96.639 28.040 1.00 23.88 ? 411 VAL A C 1 ATOM 3278 O O . VAL A 1 411 ? 29.013 96.922 28.862 1.00 24.93 ? 411 VAL A O 1 ATOM 3279 C CB . VAL A 1 411 ? 25.581 96.897 28.264 1.00 22.66 ? 411 VAL A CB 1 ATOM 3280 C CG1 . VAL A 1 411 ? 24.276 96.105 28.453 1.00 23.18 ? 411 VAL A CG1 1 ATOM 3281 C CG2 . VAL A 1 411 ? 25.603 98.049 29.226 1.00 20.36 ? 411 VAL A CG2 1 ATOM 3282 N N . PHE A 1 412 ? 28.292 96.879 26.750 1.00 24.12 ? 412 PHE A N 1 ATOM 3283 C CA . PHE A 1 412 ? 29.561 97.345 26.171 1.00 23.10 ? 412 PHE A CA 1 ATOM 3284 C C . PHE A 1 412 ? 29.275 98.571 25.331 1.00 22.73 ? 412 PHE A C 1 ATOM 3285 O O . PHE A 1 412 ? 28.411 98.543 24.470 1.00 23.47 ? 412 PHE A O 1 ATOM 3286 C CB . PHE A 1 412 ? 30.150 96.240 25.295 1.00 22.59 ? 412 PHE A CB 1 ATOM 3287 C CG . PHE A 1 412 ? 30.389 94.943 26.039 1.00 22.16 ? 412 PHE A CG 1 ATOM 3288 C CD1 . PHE A 1 412 ? 31.594 94.690 26.621 1.00 19.91 ? 412 PHE A CD1 1 ATOM 3289 C CD2 . PHE A 1 412 ? 29.376 94.004 26.186 1.00 19.70 ? 412 PHE A CD2 1 ATOM 3290 C CE1 . PHE A 1 412 ? 31.827 93.497 27.324 1.00 21.65 ? 412 PHE A CE1 1 ATOM 3291 C CE2 . PHE A 1 412 ? 29.595 92.829 26.888 1.00 19.27 ? 412 PHE A CE2 1 ATOM 3292 C CZ . PHE A 1 412 ? 30.838 92.574 27.446 1.00 22.31 ? 412 PHE A CZ 1 ATOM 3293 N N . PRO A 1 413 ? 29.986 99.663 25.588 1.00 22.33 ? 413 PRO A N 1 ATOM 3294 C CA . PRO A 1 413 ? 29.813 100.840 24.737 1.00 21.88 ? 413 PRO A CA 1 ATOM 3295 C C . PRO A 1 413 ? 30.237 100.586 23.285 1.00 22.35 ? 413 PRO A C 1 ATOM 3296 O O . PRO A 1 413 ? 31.194 99.838 23.014 1.00 22.60 ? 413 PRO A O 1 ATOM 3297 C CB . PRO A 1 413 ? 30.677 101.915 25.410 1.00 21.98 ? 413 PRO A CB 1 ATOM 3298 C CG . PRO A 1 413 ? 31.170 101.342 26.687 1.00 22.72 ? 413 PRO A CG 1 ATOM 3299 C CD . PRO A 1 413 ? 30.985 99.848 26.646 1.00 22.47 ? 413 PRO A CD 1 ATOM 3300 N N . ASP A 1 414 ? 29.521 101.188 22.350 1.00 22.33 ? 414 ASP A N 1 ATOM 3301 C CA . ASP A 1 414 ? 29.892 101.128 20.955 1.00 23.47 ? 414 ASP A CA 1 ATOM 3302 C C . ASP A 1 414 ? 30.643 102.404 20.659 1.00 23.56 ? 414 ASP A C 1 ATOM 3303 O O . ASP A 1 414 ? 30.046 103.420 20.317 1.00 24.51 ? 414 ASP A O 1 ATOM 3304 C CB . ASP A 1 414 ? 28.650 101.016 20.064 1.00 23.95 ? 414 ASP A CB 1 ATOM 3305 C CG . ASP A 1 414 ? 28.948 101.227 18.586 1.00 24.53 ? 414 ASP A CG 1 ATOM 3306 O OD1 . ASP A 1 414 ? 30.114 101.106 18.165 1.00 26.44 ? 414 ASP A OD1 1 ATOM 3307 O OD2 . ASP A 1 414 ? 27.992 101.510 17.828 1.00 25.38 ? 414 ASP A OD2 1 ATOM 3308 N N . TYR A 1 415 ? 31.952 102.371 20.839 1.00 23.10 ? 415 TYR A N 1 ATOM 3309 C CA . TYR A 1 415 ? 32.757 103.589 20.675 1.00 22.03 ? 415 TYR A CA 1 ATOM 3310 C C . TYR A 1 415 ? 32.841 104.008 19.227 1.00 22.47 ? 415 TYR A C 1 ATOM 3311 O O . TYR A 1 415 ? 33.359 105.076 18.949 1.00 23.42 ? 415 TYR A O 1 ATOM 3312 C CB . TYR A 1 415 ? 34.172 103.427 21.295 1.00 20.29 ? 415 TYR A CB 1 ATOM 3313 C CG . TYR A 1 415 ? 34.181 103.173 22.794 1.00 17.61 ? 415 TYR A CG 1 ATOM 3314 C CD1 . TYR A 1 415 ? 33.985 104.209 23.701 1.00 15.22 ? 415 TYR A CD1 1 ATOM 3315 C CD2 . TYR A 1 415 ? 34.424 101.917 23.300 1.00 16.99 ? 415 TYR A CD2 1 ATOM 3316 C CE1 . TYR A 1 415 ? 34.012 103.990 25.069 1.00 16.73 ? 415 TYR A CE1 1 ATOM 3317 C CE2 . TYR A 1 415 ? 34.426 101.683 24.692 1.00 19.60 ? 415 TYR A CE2 1 ATOM 3318 C CZ . TYR A 1 415 ? 34.208 102.733 25.563 1.00 17.65 ? 415 TYR A CZ 1 ATOM 3319 O OH . TYR A 1 415 ? 34.215 102.528 26.927 1.00 17.36 ? 415 TYR A OH 1 ATOM 3320 N N . THR A 1 416 ? 32.319 103.203 18.297 1.00 24.01 ? 416 THR A N 1 ATOM 3321 C CA . THR A 1 416 ? 32.284 103.610 16.877 1.00 25.40 ? 416 THR A CA 1 ATOM 3322 C C . THR A 1 416 ? 31.191 104.642 16.573 1.00 26.48 ? 416 THR A C 1 ATOM 3323 O O . THR A 1 416 ? 31.258 105.361 15.576 1.00 26.99 ? 416 THR A O 1 ATOM 3324 C CB . THR A 1 416 ? 32.218 102.429 15.871 1.00 24.78 ? 416 THR A CB 1 ATOM 3325 O OG1 . THR A 1 416 ? 30.899 101.874 15.829 1.00 27.83 ? 416 THR A OG1 1 ATOM 3326 C CG2 . THR A 1 416 ? 33.213 101.346 16.213 1.00 24.57 ? 416 THR A CG2 1 ATOM 3327 N N . ASN A 1 417 ? 30.192 104.705 17.443 1.00 28.39 ? 417 ASN A N 1 ATOM 3328 C CA . ASN A 1 417 ? 29.106 105.660 17.358 1.00 29.19 ? 417 ASN A CA 1 ATOM 3329 C C . ASN A 1 417 ? 29.618 106.978 17.930 1.00 30.62 ? 417 ASN A C 1 ATOM 3330 O O . ASN A 1 417 ? 30.011 107.009 19.095 1.00 30.79 ? 417 ASN A O 1 ATOM 3331 C CB . ASN A 1 417 ? 27.953 105.139 18.212 1.00 29.56 ? 417 ASN A CB 1 ATOM 3332 C CG . ASN A 1 417 ? 26.702 106.018 18.131 1.00 30.29 ? 417 ASN A CG 1 ATOM 3333 O OD1 . ASN A 1 417 ? 26.789 107.208 17.865 1.00 31.12 ? 417 ASN A OD1 1 ATOM 3334 N ND2 . ASN A 1 417 ? 25.544 105.431 18.403 1.00 29.04 ? 417 ASN A ND2 1 ATOM 3335 N N . PRO A 1 418 ? 29.635 108.073 17.125 1.00 31.89 ? 418 PRO A N 1 ATOM 3336 C CA . PRO A 1 418 ? 30.131 109.374 17.650 1.00 32.86 ? 418 PRO A CA 1 ATOM 3337 C C . PRO A 1 418 ? 29.327 109.922 18.856 1.00 32.91 ? 418 PRO A C 1 ATOM 3338 O O . PRO A 1 418 ? 29.854 110.680 19.666 1.00 32.80 ? 418 PRO A O 1 ATOM 3339 C CB . PRO A 1 418 ? 30.017 110.304 16.437 1.00 33.59 ? 418 PRO A CB 1 ATOM 3340 C CG . PRO A 1 418 ? 28.968 109.634 15.545 1.00 33.78 ? 418 PRO A CG 1 ATOM 3341 C CD . PRO A 1 418 ? 29.221 108.176 15.714 1.00 31.81 ? 418 PRO A CD 1 ATOM 3342 N N . ASN A 1 419 ? 28.070 109.504 18.977 1.00 32.80 ? 419 ASN A N 1 ATOM 3343 C CA . ASN A 1 419 ? 27.264 109.793 20.150 1.00 32.62 ? 419 ASN A CA 1 ATOM 3344 C C . ASN A 1 419 ? 27.731 109.054 21.423 1.00 32.09 ? 419 ASN A C 1 ATOM 3345 O O . ASN A 1 419 ? 27.389 109.469 22.545 1.00 31.28 ? 419 ASN A O 1 ATOM 3346 C CB . ASN A 1 419 ? 25.797 109.477 19.860 1.00 33.41 ? 419 ASN A CB 1 ATOM 3347 C CG . ASN A 1 419 ? 24.857 110.334 20.665 1.00 37.24 ? 419 ASN A CG 1 ATOM 3348 O OD1 . ASN A 1 419 ? 23.922 109.824 21.330 1.00 40.54 ? 419 ASN A OD1 1 ATOM 3349 N ND2 . ASN A 1 419 ? 25.091 111.658 20.626 1.00 38.89 ? 419 ASN A ND2 1 ATOM 3350 N N . CYS A 1 420 ? 28.515 107.978 21.252 1.00 31.37 ? 420 CYS A N 1 ATOM 3351 C CA . CYS A 1 420 ? 29.127 107.281 22.379 1.00 30.74 ? 420 CYS A CA 1 ATOM 3352 C C . CYS A 1 420 ? 30.227 108.095 23.036 1.00 30.82 ? 420 CYS A C 1 ATOM 3353 O O . CYS A 1 420 ? 30.289 108.156 24.267 1.00 31.65 ? 420 CYS A O 1 ATOM 3354 C CB . CYS A 1 420 ? 29.681 105.922 21.970 1.00 30.86 ? 420 CYS A CB 1 ATOM 3355 S SG . CYS A 1 420 ? 30.191 104.873 23.374 1.00 31.30 ? 420 CYS A SG 1 ATOM 3356 N N . ALA A 1 421 ? 31.083 108.738 22.236 1.00 30.48 ? 421 ALA A N 1 ATOM 3357 C CA . ALA A 1 421 ? 32.106 109.661 22.754 1.00 29.88 ? 421 ALA A CA 1 ATOM 3358 C C . ALA A 1 421 ? 31.476 110.782 23.610 1.00 29.86 ? 421 ALA A C 1 ATOM 3359 O O . ALA A 1 421 ? 32.025 111.161 24.646 1.00 30.79 ? 421 ALA A O 1 ATOM 3360 C CB . ALA A 1 421 ? 32.938 110.257 21.595 1.00 29.42 ? 421 ALA A CB 1 ATOM 3361 N N . VAL A 1 422 ? 30.322 111.292 23.179 1.00 29.21 ? 422 VAL A N 1 ATOM 3362 C CA . VAL A 1 422 ? 29.529 112.247 23.977 1.00 28.26 ? 422 VAL A CA 1 ATOM 3363 C C . VAL A 1 422 ? 29.199 111.675 25.350 1.00 27.40 ? 422 VAL A C 1 ATOM 3364 O O . VAL A 1 422 ? 29.560 112.267 26.373 1.00 27.51 ? 422 VAL A O 1 ATOM 3365 C CB . VAL A 1 422 ? 28.263 112.740 23.216 1.00 28.20 ? 422 VAL A CB 1 ATOM 3366 C CG1 . VAL A 1 422 ? 27.401 113.665 24.112 1.00 27.95 ? 422 VAL A CG1 1 ATOM 3367 C CG2 . VAL A 1 422 ? 28.678 113.454 21.940 1.00 28.02 ? 422 VAL A CG2 1 ATOM 3368 N N . TRP A 1 423 ? 28.560 110.503 25.382 1.00 26.92 ? 423 TRP A N 1 ATOM 3369 C CA . TRP A 1 423 ? 28.302 109.786 26.647 1.00 25.71 ? 423 TRP A CA 1 ATOM 3370 C C . TRP A 1 423 ? 29.586 109.620 27.508 1.00 25.00 ? 423 TRP A C 1 ATOM 3371 O O . TRP A 1 423 ? 29.622 109.930 28.712 1.00 25.16 ? 423 TRP A O 1 ATOM 3372 C CB . TRP A 1 423 ? 27.639 108.412 26.359 1.00 26.11 ? 423 TRP A CB 1 ATOM 3373 C CG . TRP A 1 423 ? 27.651 107.505 27.551 1.00 25.66 ? 423 TRP A CG 1 ATOM 3374 C CD1 . TRP A 1 423 ? 26.823 107.580 28.629 1.00 25.58 ? 423 TRP A CD1 1 ATOM 3375 C CD2 . TRP A 1 423 ? 28.564 106.404 27.817 1.00 24.69 ? 423 TRP A CD2 1 ATOM 3376 N NE1 . TRP A 1 423 ? 27.147 106.590 29.545 1.00 25.51 ? 423 TRP A NE1 1 ATOM 3377 C CE2 . TRP A 1 423 ? 28.210 105.861 29.073 1.00 23.92 ? 423 TRP A CE2 1 ATOM 3378 C CE3 . TRP A 1 423 ? 29.639 105.828 27.113 1.00 25.51 ? 423 TRP A CE3 1 ATOM 3379 C CZ2 . TRP A 1 423 ? 28.894 104.768 29.654 1.00 24.59 ? 423 TRP A CZ2 1 ATOM 3380 C CZ3 . TRP A 1 423 ? 30.315 104.743 27.695 1.00 25.52 ? 423 TRP A CZ3 1 ATOM 3381 C CH2 . TRP A 1 423 ? 29.929 104.223 28.951 1.00 24.78 ? 423 TRP A CH2 1 ATOM 3382 N N . TRP A 1 424 ? 30.631 109.109 26.876 1.00 24.19 ? 424 TRP A N 1 ATOM 3383 C CA . TRP A 1 424 ? 31.877 108.731 27.539 1.00 23.37 ? 424 TRP A CA 1 ATOM 3384 C C . TRP A 1 424 ? 32.522 109.991 28.133 1.00 23.13 ? 424 TRP A C 1 ATOM 3385 O O . TRP A 1 424 ? 32.945 110.003 29.282 1.00 24.15 ? 424 TRP A O 1 ATOM 3386 C CB . TRP A 1 424 ? 32.773 108.118 26.457 1.00 21.90 ? 424 TRP A CB 1 ATOM 3387 C CG . TRP A 1 424 ? 34.051 107.441 26.840 1.00 21.77 ? 424 TRP A CG 1 ATOM 3388 C CD1 . TRP A 1 424 ? 35.311 107.699 26.303 1.00 19.23 ? 424 TRP A CD1 1 ATOM 3389 C CD2 . TRP A 1 424 ? 34.226 106.348 27.754 1.00 20.61 ? 424 TRP A CD2 1 ATOM 3390 N NE1 . TRP A 1 424 ? 36.231 106.852 26.852 1.00 19.97 ? 424 TRP A NE1 1 ATOM 3391 C CE2 . TRP A 1 424 ? 35.606 106.005 27.733 1.00 20.43 ? 424 TRP A CE2 1 ATOM 3392 C CE3 . TRP A 1 424 ? 33.363 105.635 28.610 1.00 19.30 ? 424 TRP A CE3 1 ATOM 3393 C CZ2 . TRP A 1 424 ? 36.135 104.972 28.520 1.00 20.56 ? 424 TRP A CZ2 1 ATOM 3394 C CZ3 . TRP A 1 424 ? 33.898 104.594 29.387 1.00 20.53 ? 424 TRP A CZ3 1 ATOM 3395 C CH2 . TRP A 1 424 ? 35.270 104.283 29.343 1.00 20.70 ? 424 TRP A CH2 1 ATOM 3396 N N . THR A 1 425 ? 32.575 111.052 27.345 1.00 23.48 ? 425 THR A N 1 ATOM 3397 C CA . THR A 1 425 ? 33.081 112.336 27.804 1.00 24.41 ? 425 THR A CA 1 ATOM 3398 C C . THR A 1 425 ? 32.371 112.829 29.068 1.00 25.04 ? 425 THR A C 1 ATOM 3399 O O . THR A 1 425 ? 33.035 113.208 30.027 1.00 25.20 ? 425 THR A O 1 ATOM 3400 C CB . THR A 1 425 ? 33.021 113.380 26.675 1.00 24.42 ? 425 THR A CB 1 ATOM 3401 O OG1 . THR A 1 425 ? 33.794 112.898 25.555 1.00 23.50 ? 425 THR A OG1 1 ATOM 3402 C CG2 . THR A 1 425 ? 33.557 114.764 27.142 1.00 23.82 ? 425 THR A CG2 1 ATOM 3403 N N . LYS A 1 426 ? 31.035 112.788 29.091 1.00 26.36 ? 426 LYS A N 1 ATOM 3404 C CA . LYS A 1 426 ? 30.285 113.244 30.271 1.00 26.49 ? 426 LYS A CA 1 ATOM 3405 C C . LYS A 1 426 ? 30.607 112.353 31.486 1.00 26.47 ? 426 LYS A C 1 ATOM 3406 O O . LYS A 1 426 ? 30.676 112.836 32.617 1.00 25.94 ? 426 LYS A O 1 ATOM 3407 C CB . LYS A 1 426 ? 28.770 113.242 30.013 1.00 27.83 ? 426 LYS A CB 1 ATOM 3408 C CG . LYS A 1 426 ? 27.951 113.920 31.142 1.00 29.27 ? 426 LYS A CG 1 ATOM 3409 C CD . LYS A 1 426 ? 28.240 115.421 31.131 1.00 33.22 ? 426 LYS A CD 1 ATOM 3410 C CE . LYS A 1 426 ? 27.472 116.208 32.191 1.00 37.06 ? 426 LYS A CE 1 ATOM 3411 N NZ . LYS A 1 426 ? 28.253 117.471 32.594 1.00 38.29 ? 426 LYS A NZ 1 ATOM 3412 N N . GLU A 1 427 ? 30.815 111.057 31.256 1.00 26.36 ? 427 GLU A N 1 ATOM 3413 C CA . GLU A 1 427 ? 31.143 110.162 32.370 1.00 26.98 ? 427 GLU A CA 1 ATOM 3414 C C . GLU A 1 427 ? 32.460 110.589 32.993 1.00 26.22 ? 427 GLU A C 1 ATOM 3415 O O . GLU A 1 427 ? 32.577 110.623 34.216 1.00 25.51 ? 427 GLU A O 1 ATOM 3416 C CB . GLU A 1 427 ? 31.194 108.693 31.945 1.00 26.83 ? 427 GLU A CB 1 ATOM 3417 C CG . GLU A 1 427 ? 29.845 108.111 31.524 1.00 28.52 ? 427 GLU A CG 1 ATOM 3418 C CD . GLU A 1 427 ? 28.777 108.231 32.583 1.00 32.25 ? 427 GLU A CD 1 ATOM 3419 O OE1 . GLU A 1 427 ? 29.054 108.108 33.798 1.00 34.28 ? 427 GLU A OE1 1 ATOM 3420 O OE2 . GLU A 1 427 ? 27.630 108.460 32.198 1.00 35.75 ? 427 GLU A OE2 1 ATOM 3421 N N . PHE A 1 428 ? 33.419 110.946 32.138 1.00 26.26 ? 428 PHE A N 1 ATOM 3422 C CA . PHE A 1 428 ? 34.726 111.446 32.596 1.00 27.32 ? 428 PHE A CA 1 ATOM 3423 C C . PHE A 1 428 ? 34.655 112.786 33.297 1.00 27.42 ? 428 PHE A C 1 ATOM 3424 O O . PHE A 1 428 ? 35.263 112.953 34.328 1.00 27.81 ? 428 PHE A O 1 ATOM 3425 C CB . PHE A 1 428 ? 35.761 111.460 31.467 1.00 27.25 ? 428 PHE A CB 1 ATOM 3426 C CG . PHE A 1 428 ? 36.418 110.133 31.258 1.00 27.60 ? 428 PHE A CG 1 ATOM 3427 C CD1 . PHE A 1 428 ? 37.324 109.635 32.194 1.00 33.04 ? 428 PHE A CD1 1 ATOM 3428 C CD2 . PHE A 1 428 ? 36.105 109.352 30.180 1.00 27.80 ? 428 PHE A CD2 1 ATOM 3429 C CE1 . PHE A 1 428 ? 37.939 108.357 32.012 1.00 31.80 ? 428 PHE A CE1 1 ATOM 3430 C CE2 . PHE A 1 428 ? 36.720 108.102 29.989 1.00 29.37 ? 428 PHE A CE2 1 ATOM 3431 C CZ . PHE A 1 428 ? 37.620 107.611 30.906 1.00 28.35 ? 428 PHE A CZ 1 ATOM 3432 N N . GLU A 1 429 ? 33.903 113.726 32.730 1.00 28.85 ? 429 GLU A N 1 ATOM 3433 C CA . GLU A 1 429 ? 33.590 115.008 33.375 1.00 30.02 ? 429 GLU A CA 1 ATOM 3434 C C . GLU A 1 429 ? 33.001 114.811 34.768 1.00 29.29 ? 429 GLU A C 1 ATOM 3435 O O . GLU A 1 429 ? 33.516 115.347 35.743 1.00 29.14 ? 429 GLU A O 1 ATOM 3436 C CB . GLU A 1 429 ? 32.539 115.730 32.565 1.00 30.52 ? 429 GLU A CB 1 ATOM 3437 C CG . GLU A 1 429 ? 33.046 116.651 31.526 1.00 36.95 ? 429 GLU A CG 1 ATOM 3438 C CD . GLU A 1 429 ? 31.986 117.726 31.222 1.00 46.26 ? 429 GLU A CD 1 ATOM 3439 O OE1 . GLU A 1 429 ? 30.779 117.464 31.515 1.00 46.66 ? 429 GLU A OE1 1 ATOM 3440 O OE2 . GLU A 1 429 ? 32.359 118.820 30.709 1.00 48.81 ? 429 GLU A OE2 1 ATOM 3441 N N . LEU A 1 430 ? 31.925 114.032 34.853 1.00 28.49 ? 430 LEU A N 1 ATOM 3442 C CA . LEU A 1 430 ? 31.293 113.786 36.140 1.00 29.02 ? 430 LEU A CA 1 ATOM 3443 C C . LEU A 1 430 ? 32.270 113.185 37.150 1.00 28.57 ? 430 LEU A C 1 ATOM 3444 O O . LEU A 1 430 ? 32.325 113.647 38.293 1.00 29.41 ? 430 LEU A O 1 ATOM 3445 C CB . LEU A 1 430 ? 30.002 112.949 36.015 1.00 28.76 ? 430 LEU A CB 1 ATOM 3446 C CG . LEU A 1 430 ? 28.824 113.483 35.161 1.00 31.57 ? 430 LEU A CG 1 ATOM 3447 C CD1 . LEU A 1 430 ? 27.709 112.441 35.062 1.00 33.18 ? 430 LEU A CD1 1 ATOM 3448 C CD2 . LEU A 1 430 ? 28.229 114.817 35.671 1.00 34.60 ? 430 LEU A CD2 1 ATOM 3449 N N . PHE A 1 431 ? 33.056 112.181 36.741 1.00 27.40 ? 431 PHE A N 1 ATOM 3450 C CA . PHE A 1 431 ? 34.006 111.538 37.655 1.00 26.59 ? 431 PHE A CA 1 ATOM 3451 C C . PHE A 1 431 ? 35.195 112.422 38.061 1.00 27.34 ? 431 PHE A C 1 ATOM 3452 O O . PHE A 1 431 ? 35.690 112.330 39.204 1.00 27.26 ? 431 PHE A O 1 ATOM 3453 C CB . PHE A 1 431 ? 34.489 110.186 37.085 1.00 25.79 ? 431 PHE A CB 1 ATOM 3454 C CG . PHE A 1 431 ? 35.142 109.288 38.109 1.00 26.60 ? 431 PHE A CG 1 ATOM 3455 C CD1 . PHE A 1 431 ? 34.532 109.058 39.351 1.00 26.19 ? 431 PHE A CD1 1 ATOM 3456 C CD2 . PHE A 1 431 ? 36.365 108.666 37.837 1.00 23.78 ? 431 PHE A CD2 1 ATOM 3457 C CE1 . PHE A 1 431 ? 35.136 108.225 40.306 1.00 26.03 ? 431 PHE A CE1 1 ATOM 3458 C CE2 . PHE A 1 431 ? 36.974 107.842 38.793 1.00 25.74 ? 431 PHE A CE2 1 ATOM 3459 C CZ . PHE A 1 431 ? 36.363 107.614 40.021 1.00 25.63 ? 431 PHE A CZ 1 ATOM 3460 N N . HIS A 1 432 ? 35.668 113.262 37.139 1.00 28.23 ? 432 HIS A N 1 ATOM 3461 C CA . HIS A 1 432 ? 36.819 114.144 37.419 1.00 29.69 ? 432 HIS A CA 1 ATOM 3462 C C . HIS A 1 432 ? 36.511 115.201 38.499 1.00 30.92 ? 432 HIS A C 1 ATOM 3463 O O . HIS A 1 432 ? 37.393 115.631 39.226 1.00 31.05 ? 432 HIS A O 1 ATOM 3464 C CB . HIS A 1 432 ? 37.281 114.830 36.150 1.00 29.40 ? 432 HIS A CB 1 ATOM 3465 C CG . HIS A 1 432 ? 38.626 115.479 36.273 1.00 30.47 ? 432 HIS A CG 1 ATOM 3466 N ND1 . HIS A 1 432 ? 38.784 116.829 36.495 1.00 33.01 ? 432 HIS A ND1 1 ATOM 3467 C CD2 . HIS A 1 432 ? 39.877 114.964 36.208 1.00 30.90 ? 432 HIS A CD2 1 ATOM 3468 C CE1 . HIS A 1 432 ? 40.072 117.117 36.581 1.00 31.49 ? 432 HIS A CE1 1 ATOM 3469 N NE2 . HIS A 1 432 ? 40.758 116.006 36.383 1.00 30.12 ? 432 HIS A NE2 1 ATOM 3470 N N . ASN A 1 433 ? 35.246 115.612 38.580 1.00 32.25 ? 433 ASN A N 1 ATOM 3471 C CA . ASN A 1 433 ? 34.755 116.433 39.667 1.00 33.91 ? 433 ASN A CA 1 ATOM 3472 C C . ASN A 1 433 ? 34.932 115.792 41.051 1.00 34.29 ? 433 ASN A C 1 ATOM 3473 O O . ASN A 1 433 ? 35.047 116.490 42.045 1.00 35.58 ? 433 ASN A O 1 ATOM 3474 C CB . ASN A 1 433 ? 33.279 116.798 39.407 1.00 34.62 ? 433 ASN A CB 1 ATOM 3475 C CG . ASN A 1 433 ? 33.097 117.630 38.145 1.00 37.25 ? 433 ASN A CG 1 ATOM 3476 O OD1 . ASN A 1 433 ? 34.009 118.355 37.728 1.00 42.16 ? 433 ASN A OD1 1 ATOM 3477 N ND2 . ASN A 1 433 ? 31.914 117.546 37.534 1.00 39.94 ? 433 ASN A ND2 1 ATOM 3478 N N . GLN A 1 434 ? 34.957 114.469 41.120 1.00 35.01 ? 434 GLN A N 1 ATOM 3479 C CA . GLN A 1 434 ? 35.161 113.763 42.382 1.00 35.52 ? 434 GLN A CA 1 ATOM 3480 C C . GLN A 1 434 ? 36.645 113.424 42.633 1.00 35.32 ? 434 GLN A C 1 ATOM 3481 O O . GLN A 1 434 ? 37.196 113.702 43.713 1.00 35.64 ? 434 GLN A O 1 ATOM 3482 C CB . GLN A 1 434 ? 34.335 112.475 42.399 1.00 36.29 ? 434 GLN A CB 1 ATOM 3483 C CG . GLN A 1 434 ? 32.873 112.658 42.090 1.00 39.58 ? 434 GLN A CG 1 ATOM 3484 C CD . GLN A 1 434 ? 32.114 111.385 42.302 1.00 45.54 ? 434 GLN A CD 1 ATOM 3485 O OE1 . GLN A 1 434 ? 31.656 110.753 41.337 1.00 49.71 ? 434 GLN A OE1 1 ATOM 3486 N NE2 . GLN A 1 434 ? 31.988 110.969 43.571 1.00 47.63 ? 434 GLN A NE2 1 ATOM 3487 N N . VAL A 1 435 ? 37.281 112.807 41.632 1.00 34.30 ? 435 VAL A N 1 ATOM 3488 C CA . VAL A 1 435 ? 38.656 112.361 41.742 1.00 32.26 ? 435 VAL A CA 1 ATOM 3489 C C . VAL A 1 435 ? 39.387 112.998 40.589 1.00 31.90 ? 435 VAL A C 1 ATOM 3490 O O . VAL A 1 435 ? 39.115 112.674 39.440 1.00 31.67 ? 435 VAL A O 1 ATOM 3491 C CB . VAL A 1 435 ? 38.751 110.832 41.645 1.00 32.77 ? 435 VAL A CB 1 ATOM 3492 C CG1 . VAL A 1 435 ? 40.201 110.363 41.889 1.00 33.01 ? 435 VAL A CG1 1 ATOM 3493 C CG2 . VAL A 1 435 ? 37.785 110.169 42.624 1.00 31.44 ? 435 VAL A CG2 1 ATOM 3494 N N . GLU A 1 436 ? 40.305 113.922 40.888 1.00 30.63 ? 436 GLU A N 1 ATOM 3495 C CA . GLU A 1 436 ? 41.017 114.681 39.861 1.00 30.31 ? 436 GLU A CA 1 ATOM 3496 C C . GLU A 1 436 ? 42.210 113.893 39.287 1.00 28.03 ? 436 GLU A C 1 ATOM 3497 O O . GLU A 1 436 ? 43.362 114.205 39.555 1.00 27.79 ? 436 GLU A O 1 ATOM 3498 C CB . GLU A 1 436 ? 41.472 116.037 40.419 1.00 29.77 ? 436 GLU A CB 1 ATOM 3499 C CG . GLU A 1 436 ? 40.299 116.991 40.714 1.00 33.84 ? 436 GLU A CG 1 ATOM 3500 C CD . GLU A 1 436 ? 40.763 118.361 41.241 1.00 34.92 ? 436 GLU A CD 1 ATOM 3501 O OE1 . GLU A 1 436 ? 41.417 119.120 40.476 1.00 42.86 ? 436 GLU A OE1 1 ATOM 3502 O OE2 . GLU A 1 436 ? 40.475 118.676 42.415 1.00 39.12 ? 436 GLU A OE2 1 ATOM 3503 N N . PHE A 1 437 ? 41.905 112.866 38.503 1.00 26.15 ? 437 PHE A N 1 ATOM 3504 C CA . PHE A 1 437 ? 42.916 112.079 37.798 1.00 23.75 ? 437 PHE A CA 1 ATOM 3505 C C . PHE A 1 437 ? 43.555 112.920 36.672 1.00 23.29 ? 437 PHE A C 1 ATOM 3506 O O . PHE A 1 437 ? 43.005 113.947 36.238 1.00 23.12 ? 437 PHE A O 1 ATOM 3507 C CB . PHE A 1 437 ? 42.274 110.795 37.271 1.00 23.11 ? 437 PHE A CB 1 ATOM 3508 C CG . PHE A 1 437 ? 41.104 111.040 36.382 1.00 22.84 ? 437 PHE A CG 1 ATOM 3509 C CD1 . PHE A 1 437 ? 41.289 111.264 35.007 1.00 24.72 ? 437 PHE A CD1 1 ATOM 3510 C CD2 . PHE A 1 437 ? 39.816 111.072 36.894 1.00 22.76 ? 437 PHE A CD2 1 ATOM 3511 C CE1 . PHE A 1 437 ? 40.197 111.532 34.159 1.00 24.51 ? 437 PHE A CE1 1 ATOM 3512 C CE2 . PHE A 1 437 ? 38.734 111.315 36.075 1.00 22.22 ? 437 PHE A CE2 1 ATOM 3513 C CZ . PHE A 1 437 ? 38.910 111.561 34.707 1.00 23.35 ? 437 PHE A CZ 1 ATOM 3514 N N . ASP A 1 438 ? 44.732 112.511 36.215 1.00 22.35 ? 438 ASP A N 1 ATOM 3515 C CA . ASP A 1 438 ? 45.482 113.290 35.250 1.00 21.69 ? 438 ASP A CA 1 ATOM 3516 C C . ASP A 1 438 ? 45.591 112.564 33.933 1.00 21.47 ? 438 ASP A C 1 ATOM 3517 O O . ASP A 1 438 ? 45.912 113.164 32.908 1.00 22.00 ? 438 ASP A O 1 ATOM 3518 C CB . ASP A 1 438 ? 46.890 113.553 35.809 1.00 21.79 ? 438 ASP A CB 1 ATOM 3519 C CG . ASP A 1 438 ? 46.838 114.317 37.126 1.00 22.88 ? 438 ASP A CG 1 ATOM 3520 O OD1 . ASP A 1 438 ? 46.343 115.462 37.039 1.00 22.54 ? 438 ASP A OD1 1 ATOM 3521 O OD2 . ASP A 1 438 ? 47.233 113.773 38.218 1.00 22.33 ? 438 ASP A OD2 1 ATOM 3522 N N . GLY A 1 439 ? 45.391 111.254 33.982 1.00 20.98 ? 439 GLY A N 1 ATOM 3523 C CA . GLY A 1 439 ? 45.497 110.418 32.797 1.00 20.67 ? 439 GLY A CA 1 ATOM 3524 C C . GLY A 1 439 ? 44.646 109.188 32.979 1.00 20.19 ? 439 GLY A C 1 ATOM 3525 O O . GLY A 1 439 ? 44.110 108.939 34.060 1.00 19.12 ? 439 GLY A O 1 ATOM 3526 N N . ILE A 1 440 ? 44.564 108.403 31.917 1.00 21.11 ? 440 ILE A N 1 ATOM 3527 C CA . ILE A 1 440 ? 43.564 107.336 31.796 1.00 21.13 ? 440 ILE A CA 1 ATOM 3528 C C . ILE A 1 440 ? 44.222 106.083 31.235 1.00 21.06 ? 440 ILE A C 1 ATOM 3529 O O . ILE A 1 440 ? 44.872 106.144 30.214 1.00 21.39 ? 440 ILE A O 1 ATOM 3530 C CB . ILE A 1 440 ? 42.402 107.760 30.863 1.00 21.31 ? 440 ILE A CB 1 ATOM 3531 C CG1 . ILE A 1 440 ? 41.719 109.023 31.427 1.00 23.26 ? 440 ILE A CG1 1 ATOM 3532 C CG2 . ILE A 1 440 ? 41.376 106.648 30.759 1.00 21.59 ? 440 ILE A CG2 1 ATOM 3533 C CD1 . ILE A 1 440 ? 40.961 109.824 30.413 1.00 24.12 ? 440 ILE A CD1 1 ATOM 3534 N N . TRP A 1 441 ? 44.028 104.968 31.929 1.00 20.52 ? 441 TRP A N 1 ATOM 3535 C CA . TRP A 1 441 ? 44.527 103.665 31.564 1.00 20.34 ? 441 TRP A CA 1 ATOM 3536 C C . TRP A 1 441 ? 43.304 102.824 31.125 1.00 20.12 ? 441 TRP A C 1 ATOM 3537 O O . TRP A 1 441 ? 42.460 102.496 31.947 1.00 19.92 ? 441 TRP A O 1 ATOM 3538 C CB . TRP A 1 441 ? 45.289 103.092 32.762 1.00 20.40 ? 441 TRP A CB 1 ATOM 3539 C CG . TRP A 1 441 ? 45.652 101.638 32.721 1.00 21.42 ? 441 TRP A CG 1 ATOM 3540 C CD1 . TRP A 1 441 ? 45.752 100.836 31.624 1.00 22.39 ? 441 TRP A CD1 1 ATOM 3541 C CD2 . TRP A 1 441 ? 45.996 100.812 33.857 1.00 22.18 ? 441 TRP A CD2 1 ATOM 3542 N NE1 . TRP A 1 441 ? 46.099 99.554 32.002 1.00 20.65 ? 441 TRP A NE1 1 ATOM 3543 C CE2 . TRP A 1 441 ? 46.258 99.518 33.365 1.00 21.27 ? 441 TRP A CE2 1 ATOM 3544 C CE3 . TRP A 1 441 ? 46.113 101.054 35.244 1.00 20.55 ? 441 TRP A CE3 1 ATOM 3545 C CZ2 . TRP A 1 441 ? 46.605 98.461 34.210 1.00 23.08 ? 441 TRP A CZ2 1 ATOM 3546 C CZ3 . TRP A 1 441 ? 46.423 100.030 36.074 1.00 20.62 ? 441 TRP A CZ3 1 ATOM 3547 C CH2 . TRP A 1 441 ? 46.706 98.742 35.563 1.00 23.01 ? 441 TRP A CH2 1 ATOM 3548 N N . ILE A 1 442 ? 43.181 102.576 29.816 1.00 19.95 ? 442 ILE A N 1 ATOM 3549 C CA . ILE A 1 442 ? 42.062 101.818 29.242 1.00 20.70 ? 442 ILE A CA 1 ATOM 3550 C C . ILE A 1 442 ? 42.470 100.376 28.984 1.00 20.86 ? 442 ILE A C 1 ATOM 3551 O O . ILE A 1 442 ? 43.473 100.079 28.310 1.00 20.93 ? 442 ILE A O 1 ATOM 3552 C CB . ILE A 1 442 ? 41.387 102.496 28.007 1.00 21.21 ? 442 ILE A CB 1 ATOM 3553 C CG1 . ILE A 1 442 ? 42.394 102.805 26.870 1.00 21.43 ? 442 ILE A CG1 1 ATOM 3554 C CG2 . ILE A 1 442 ? 40.714 103.806 28.447 1.00 20.85 ? 442 ILE A CG2 1 ATOM 3555 C CD1 . ILE A 1 442 ? 41.726 103.264 25.527 1.00 20.67 ? 442 ILE A CD1 1 ATOM 3556 N N . ASP A 1 443 ? 41.703 99.479 29.589 1.00 20.91 ? 443 ASP A N 1 ATOM 3557 C CA . ASP A 1 443 ? 42.061 98.078 29.677 1.00 21.00 ? 443 ASP A CA 1 ATOM 3558 C C . ASP A 1 443 ? 40.884 97.202 29.236 1.00 21.43 ? 443 ASP A C 1 ATOM 3559 O O . ASP A 1 443 ? 39.761 97.703 29.028 1.00 20.94 ? 443 ASP A O 1 ATOM 3560 C CB . ASP A 1 443 ? 42.435 97.770 31.116 1.00 20.85 ? 443 ASP A CB 1 ATOM 3561 C CG . ASP A 1 443 ? 43.172 96.457 31.266 1.00 23.73 ? 443 ASP A CG 1 ATOM 3562 O OD1 . ASP A 1 443 ? 43.922 96.054 30.359 1.00 22.20 ? 443 ASP A OD1 1 ATOM 3563 O OD2 . ASP A 1 443 ? 43.000 95.825 32.319 1.00 28.72 ? 443 ASP A OD2 1 ATOM 3564 N N . MET A 1 444 ? 41.157 95.904 29.092 1.00 21.45 ? 444 MET A N 1 ATOM 3565 C CA . MET A 1 444 ? 40.136 94.903 28.790 1.00 20.88 ? 444 MET A CA 1 ATOM 3566 C C . MET A 1 444 ? 39.393 95.226 27.506 1.00 20.99 ? 444 MET A C 1 ATOM 3567 O O . MET A 1 444 ? 38.239 94.827 27.339 1.00 20.38 ? 444 MET A O 1 ATOM 3568 C CB . MET A 1 444 ? 39.142 94.735 29.966 1.00 20.98 ? 444 MET A CB 1 ATOM 3569 C CG . MET A 1 444 ? 39.773 94.476 31.324 1.00 18.21 ? 444 MET A CG 1 ATOM 3570 S SD . MET A 1 444 ? 40.610 92.926 31.425 1.00 23.05 ? 444 MET A SD 1 ATOM 3571 C CE . MET A 1 444 ? 39.233 91.774 31.409 1.00 21.48 ? 444 MET A CE 1 ATOM 3572 N N . ASN A 1 445 ? 40.054 95.939 26.583 1.00 20.51 ? 445 ASN A N 1 ATOM 3573 C CA . ASN A 1 445 ? 39.347 96.476 25.406 1.00 20.16 ? 445 ASN A CA 1 ATOM 3574 C C . ASN A 1 445 ? 39.599 95.747 24.065 1.00 20.43 ? 445 ASN A C 1 ATOM 3575 O O . ASN A 1 445 ? 39.559 96.348 23.013 1.00 20.92 ? 445 ASN A O 1 ATOM 3576 C CB . ASN A 1 445 ? 39.569 97.984 25.286 1.00 19.89 ? 445 ASN A CB 1 ATOM 3577 C CG . ASN A 1 445 ? 41.061 98.366 25.234 1.00 18.99 ? 445 ASN A CG 1 ATOM 3578 O OD1 . ASN A 1 445 ? 41.963 97.552 25.431 1.00 18.77 ? 445 ASN A OD1 1 ATOM 3579 N ND2 . ASN A 1 445 ? 41.303 99.604 24.962 1.00 17.71 ? 445 ASN A ND2 1 ATOM 3580 N N . GLU A 1 446 ? 39.800 94.441 24.116 1.00 21.13 ? 446 GLU A N 1 ATOM 3581 C CA . GLU A 1 446 ? 39.869 93.613 22.920 1.00 21.81 ? 446 GLU A CA 1 ATOM 3582 C C . GLU A 1 446 ? 38.607 93.482 22.063 1.00 23.03 ? 446 GLU A C 1 ATOM 3583 O O . GLU A 1 446 ? 38.719 93.432 20.844 1.00 22.82 ? 446 GLU A O 1 ATOM 3584 C CB . GLU A 1 446 ? 40.416 92.239 23.281 1.00 22.82 ? 446 GLU A CB 1 ATOM 3585 C CG . GLU A 1 446 ? 41.871 92.260 23.752 1.00 19.45 ? 446 GLU A CG 1 ATOM 3586 C CD . GLU A 1 446 ? 42.061 92.880 25.146 1.00 23.59 ? 446 GLU A CD 1 ATOM 3587 O OE1 . GLU A 1 446 ? 41.246 92.634 26.089 1.00 22.83 ? 446 GLU A OE1 1 ATOM 3588 O OE2 . GLU A 1 446 ? 43.066 93.631 25.301 1.00 26.98 ? 446 GLU A OE2 1 ATOM 3589 N N . VAL A 1 447 ? 37.396 93.431 22.617 1.00 24.68 ? 447 VAL A N 1 ATOM 3590 C CA . VAL A 1 447 ? 37.011 93.606 24.023 1.00 26.40 ? 447 VAL A CA 1 ATOM 3591 C C . VAL A 1 447 ? 37.051 92.235 24.758 1.00 26.77 ? 447 VAL A C 1 ATOM 3592 O O . VAL A 1 447 ? 36.822 91.190 24.146 1.00 28.27 ? 447 VAL A O 1 ATOM 3593 C CB . VAL A 1 447 ? 35.608 94.341 24.068 1.00 26.44 ? 447 VAL A CB 1 ATOM 3594 C CG1 . VAL A 1 447 ? 34.503 93.387 23.772 1.00 27.62 ? 447 VAL A CG1 1 ATOM 3595 C CG2 . VAL A 1 447 ? 35.361 95.046 25.396 1.00 28.01 ? 447 VAL A CG2 1 ATOM 3596 N N . SER A 1 448 ? 37.403 92.237 26.041 1.00 26.99 ? 448 SER A N 1 ATOM 3597 C CA . SER A 1 448 ? 37.539 91.023 26.848 1.00 26.73 ? 448 SER A CA 1 ATOM 3598 C C . SER A 1 448 ? 36.204 90.716 27.554 1.00 26.92 ? 448 SER A C 1 ATOM 3599 O O . SER A 1 448 ? 35.655 91.583 28.238 1.00 27.27 ? 448 SER A O 1 ATOM 3600 C CB . SER A 1 448 ? 38.640 91.224 27.863 1.00 26.12 ? 448 SER A CB 1 ATOM 3601 O OG . SER A 1 448 ? 38.854 90.100 28.719 1.00 29.34 ? 448 SER A OG 1 ATOM 3602 N N . ASN A 1 449 ? 35.688 89.496 27.370 1.00 26.32 ? 449 ASN A N 1 ATOM 3603 C CA . ASN A 1 449 ? 34.396 89.054 27.927 1.00 25.60 ? 449 ASN A CA 1 ATOM 3604 C C . ASN A 1 449 ? 34.731 87.816 28.771 1.00 26.14 ? 449 ASN A C 1 ATOM 3605 O O . ASN A 1 449 ? 35.561 86.974 28.351 1.00 25.35 ? 449 ASN A O 1 ATOM 3606 C CB . ASN A 1 449 ? 33.479 88.691 26.749 1.00 26.34 ? 449 ASN A CB 1 ATOM 3607 C CG . ASN A 1 449 ? 31.970 88.679 27.080 1.00 26.04 ? 449 ASN A CG 1 ATOM 3608 O OD1 . ASN A 1 449 ? 31.550 88.797 28.214 1.00 26.44 ? 449 ASN A OD1 1 ATOM 3609 N ND2 . ASN A 1 449 ? 31.161 88.530 26.044 1.00 25.45 ? 449 ASN A ND2 1 ATOM 3610 N N . PHE A 1 450 ? 34.154 87.733 29.972 1.00 24.84 ? 450 PHE A N 1 ATOM 3611 C CA . PHE A 1 450 ? 34.365 86.587 30.846 1.00 25.49 ? 450 PHE A CA 1 ATOM 3612 C C . PHE A 1 450 ? 33.515 85.387 30.418 1.00 26.11 ? 450 PHE A C 1 ATOM 3613 O O . PHE A 1 450 ? 33.837 84.250 30.755 1.00 26.86 ? 450 PHE A O 1 ATOM 3614 C CB . PHE A 1 450 ? 34.117 86.931 32.320 1.00 24.72 ? 450 PHE A CB 1 ATOM 3615 C CG . PHE A 1 450 ? 35.149 87.866 32.929 1.00 24.15 ? 450 PHE A CG 1 ATOM 3616 C CD1 . PHE A 1 450 ? 36.272 88.277 32.209 1.00 23.76 ? 450 PHE A CD1 1 ATOM 3617 C CD2 . PHE A 1 450 ? 34.995 88.327 34.238 1.00 23.82 ? 450 PHE A CD2 1 ATOM 3618 C CE1 . PHE A 1 450 ? 37.239 89.128 32.789 1.00 24.42 ? 450 PHE A CE1 1 ATOM 3619 C CE2 . PHE A 1 450 ? 35.961 89.182 34.816 1.00 23.34 ? 450 PHE A CE2 1 ATOM 3620 C CZ . PHE A 1 450 ? 37.080 89.569 34.083 1.00 22.94 ? 450 PHE A CZ 1 ATOM 3621 N N . VAL A 1 451 ? 32.439 85.637 29.681 1.00 26.44 ? 451 VAL A N 1 ATOM 3622 C CA . VAL A 1 451 ? 31.717 84.557 28.999 1.00 27.44 ? 451 VAL A CA 1 ATOM 3623 C C . VAL A 1 451 ? 32.046 84.554 27.487 1.00 27.93 ? 451 VAL A C 1 ATOM 3624 O O . VAL A 1 451 ? 32.506 85.556 26.939 1.00 28.64 ? 451 VAL A O 1 ATOM 3625 C CB . VAL A 1 451 ? 30.188 84.685 29.169 1.00 26.94 ? 451 VAL A CB 1 ATOM 3626 C CG1 . VAL A 1 451 ? 29.780 84.380 30.600 1.00 27.38 ? 451 VAL A CG1 1 ATOM 3627 C CG2 . VAL A 1 451 ? 29.727 86.077 28.753 1.00 27.36 ? 451 VAL A CG2 1 ATOM 3628 N N . ASP A 1 452 ? 31.785 83.440 26.812 1.00 27.45 ? 452 ASP A N 1 ATOM 3629 C CA . ASP A 1 452 ? 32.037 83.366 25.395 1.00 26.75 ? 452 ASP A CA 1 ATOM 3630 C C . ASP A 1 452 ? 30.863 83.956 24.618 1.00 26.74 ? 452 ASP A C 1 ATOM 3631 O O . ASP A 1 452 ? 29.732 83.399 24.596 1.00 26.33 ? 452 ASP A O 1 ATOM 3632 C CB . ASP A 1 452 ? 32.332 81.917 24.999 1.00 27.30 ? 452 ASP A CB 1 ATOM 3633 C CG . ASP A 1 452 ? 33.650 81.387 25.615 1.00 28.96 ? 452 ASP A CG 1 ATOM 3634 O OD1 . ASP A 1 452 ? 34.571 82.169 25.906 1.00 29.16 ? 452 ASP A OD1 1 ATOM 3635 O OD2 . ASP A 1 452 ? 33.782 80.165 25.824 1.00 33.90 ? 452 ASP A OD2 1 ATOM 3636 N N . GLY A 1 453 ? 31.115 85.114 24.011 1.00 25.15 ? 453 GLY A N 1 ATOM 3637 C CA . GLY A 1 453 ? 30.159 85.762 23.138 1.00 24.24 ? 453 GLY A CA 1 ATOM 3638 C C . GLY A 1 453 ? 29.178 86.615 23.902 1.00 25.30 ? 453 GLY A C 1 ATOM 3639 O O . GLY A 1 453 ? 29.163 87.828 23.748 1.00 23.96 ? 453 GLY A O 1 ATOM 3640 N N . SER A 1 454 ? 28.333 85.974 24.715 1.00 25.49 ? 454 SER A N 1 ATOM 3641 C CA . SER A 1 454 ? 27.331 86.695 25.508 1.00 26.00 ? 454 SER A CA 1 ATOM 3642 C C . SER A 1 454 ? 26.833 85.735 26.591 1.00 26.68 ? 454 SER A C 1 ATOM 3643 O O . SER A 1 454 ? 27.264 84.558 26.640 1.00 26.51 ? 454 SER A O 1 ATOM 3644 C CB . SER A 1 454 ? 26.168 87.205 24.639 1.00 25.79 ? 454 SER A CB 1 ATOM 3645 O OG . SER A 1 454 ? 25.158 86.207 24.405 1.00 27.31 ? 454 SER A OG 1 ATOM 3646 N N . VAL A 1 455 ? 25.933 86.223 27.448 1.00 27.19 ? 455 VAL A N 1 ATOM 3647 C CA . VAL A 1 455 ? 25.370 85.382 28.508 1.00 27.65 ? 455 VAL A CA 1 ATOM 3648 C C . VAL A 1 455 ? 24.531 84.239 27.938 1.00 28.75 ? 455 VAL A C 1 ATOM 3649 O O . VAL A 1 455 ? 24.377 83.221 28.594 1.00 28.72 ? 455 VAL A O 1 ATOM 3650 C CB . VAL A 1 455 ? 24.650 86.176 29.656 1.00 27.92 ? 455 VAL A CB 1 ATOM 3651 C CG1 . VAL A 1 455 ? 25.643 87.034 30.428 1.00 26.39 ? 455 VAL A CG1 1 ATOM 3652 C CG2 . VAL A 1 455 ? 23.465 87.022 29.136 1.00 27.37 ? 455 VAL A CG2 1 ATOM 3653 N N . SER A 1 456 ? 24.049 84.358 26.703 1.00 29.86 ? 456 SER A N 1 ATOM 3654 C CA . SER A 1 456 ? 23.387 83.200 26.076 1.00 31.87 ? 456 SER A CA 1 ATOM 3655 C C . SER A 1 456 ? 24.226 82.486 25.003 1.00 31.57 ? 456 SER A C 1 ATOM 3656 O O . SER A 1 456 ? 23.700 81.741 24.184 1.00 32.52 ? 456 SER A O 1 ATOM 3657 C CB . SER A 1 456 ? 21.985 83.560 25.559 1.00 32.17 ? 456 SER A CB 1 ATOM 3658 O OG . SER A 1 456 ? 21.969 84.823 24.896 1.00 37.10 ? 456 SER A OG 1 ATOM 3659 N N . GLY A 1 457 ? 25.540 82.673 25.043 1.00 31.97 ? 457 GLY A N 1 ATOM 3660 C CA . GLY A 1 457 ? 26.413 82.183 23.988 1.00 31.71 ? 457 GLY A CA 1 ATOM 3661 C C . GLY A 1 457 ? 26.156 82.855 22.647 1.00 31.96 ? 457 GLY A C 1 ATOM 3662 O O . GLY A 1 457 ? 25.690 83.992 22.592 1.00 31.62 ? 457 GLY A O 1 ATOM 3663 N N . CYS A 1 458 ? 26.468 82.137 21.563 1.00 32.39 ? 458 CYS A N 1 ATOM 3664 C CA . CYS A 1 458 ? 26.339 82.654 20.188 1.00 32.49 ? 458 CYS A CA 1 ATOM 3665 C C . CYS A 1 458 ? 25.637 81.660 19.306 1.00 31.56 ? 458 CYS A C 1 ATOM 3666 O O . CYS A 1 458 ? 25.990 80.502 19.301 1.00 31.55 ? 458 CYS A O 1 ATOM 3667 C CB . CYS A 1 458 ? 27.728 82.886 19.581 1.00 32.02 ? 458 CYS A CB 1 ATOM 3668 S SG . CYS A 1 458 ? 28.780 83.967 20.532 1.00 36.27 ? 458 CYS A SG 1 ATOM 3669 N N . SER A 1 459 ? 24.672 82.126 18.532 1.00 31.83 ? 459 SER A N 1 ATOM 3670 C CA . SER A 1 459 ? 24.029 81.307 17.530 1.00 32.21 ? 459 SER A CA 1 ATOM 3671 C C . SER A 1 459 ? 25.030 80.733 16.527 1.00 32.18 ? 459 SER A C 1 ATOM 3672 O O . SER A 1 459 ? 26.021 81.399 16.134 1.00 31.65 ? 459 SER A O 1 ATOM 3673 C CB . SER A 1 459 ? 23.002 82.140 16.788 1.00 32.23 ? 459 SER A CB 1 ATOM 3674 O OG . SER A 1 459 ? 22.271 82.904 17.727 1.00 35.75 ? 459 SER A OG 1 ATOM 3675 N N . THR A 1 460 ? 24.790 79.485 16.147 1.00 31.77 ? 460 THR A N 1 ATOM 3676 C CA . THR A 1 460 ? 25.543 78.839 15.092 1.00 32.55 ? 460 THR A CA 1 ATOM 3677 C C . THR A 1 460 ? 25.175 79.451 13.759 1.00 32.01 ? 460 THR A C 1 ATOM 3678 O O . THR A 1 460 ? 23.984 79.488 13.389 1.00 32.63 ? 460 THR A O 1 ATOM 3679 C CB . THR A 1 460 ? 25.255 77.365 15.046 1.00 33.01 ? 460 THR A CB 1 ATOM 3680 O OG1 . THR A 1 460 ? 25.641 76.793 16.298 1.00 35.67 ? 460 THR A OG1 1 ATOM 3681 C CG2 . THR A 1 460 ? 26.076 76.700 13.897 1.00 33.26 ? 460 THR A CG2 1 ATOM 3682 N N . ASN A 1 461 ? 26.182 79.976 13.068 1.00 30.80 ? 461 ASN A N 1 ATOM 3683 C CA . ASN A 1 461 ? 26.018 80.641 11.767 1.00 29.63 ? 461 ASN A CA 1 ATOM 3684 C C . ASN A 1 461 ? 27.387 80.970 11.153 1.00 29.29 ? 461 ASN A C 1 ATOM 3685 O O . ASN A 1 461 ? 28.392 80.731 11.791 1.00 28.98 ? 461 ASN A O 1 ATOM 3686 C CB . ASN A 1 461 ? 25.101 81.877 11.859 1.00 28.97 ? 461 ASN A CB 1 ATOM 3687 C CG . ASN A 1 461 ? 25.656 82.983 12.752 1.00 30.00 ? 461 ASN A CG 1 ATOM 3688 O OD1 . ASN A 1 461 ? 26.867 83.217 12.806 1.00 28.07 ? 461 ASN A OD1 1 ATOM 3689 N ND2 . ASN A 1 461 ? 24.758 83.702 13.426 1.00 25.05 ? 461 ASN A ND2 1 ATOM 3690 N N . ASN A 1 462 ? 27.433 81.517 9.936 1.00 28.49 ? 462 ASN A N 1 ATOM 3691 C CA . ASN A 1 462 ? 28.717 81.652 9.220 1.00 28.54 ? 462 ASN A CA 1 ATOM 3692 C C . ASN A 1 462 ? 29.669 82.732 9.790 1.00 26.90 ? 462 ASN A C 1 ATOM 3693 O O . ASN A 1 462 ? 30.864 82.759 9.464 1.00 26.51 ? 462 ASN A O 1 ATOM 3694 C CB . ASN A 1 462 ? 28.497 81.858 7.710 1.00 29.19 ? 462 ASN A CB 1 ATOM 3695 C CG . ASN A 1 462 ? 27.963 83.246 7.390 1.00 32.56 ? 462 ASN A CG 1 ATOM 3696 O OD1 . ASN A 1 462 ? 27.065 83.730 8.053 1.00 36.55 ? 462 ASN A OD1 1 ATOM 3697 N ND2 . ASN A 1 462 ? 28.538 83.900 6.388 1.00 36.41 ? 462 ASN A ND2 1 ATOM 3698 N N . LEU A 1 463 ? 29.148 83.598 10.653 1.00 25.67 ? 463 LEU A N 1 ATOM 3699 C CA . LEU A 1 463 ? 29.975 84.607 11.338 1.00 24.86 ? 463 LEU A CA 1 ATOM 3700 C C . LEU A 1 463 ? 30.610 84.031 12.587 1.00 24.89 ? 463 LEU A C 1 ATOM 3701 O O . LEU A 1 463 ? 31.837 84.051 12.724 1.00 23.56 ? 463 LEU A O 1 ATOM 3702 C CB . LEU A 1 463 ? 29.177 85.871 11.651 1.00 24.67 ? 463 LEU A CB 1 ATOM 3703 C CG . LEU A 1 463 ? 28.521 86.546 10.433 1.00 25.56 ? 463 LEU A CG 1 ATOM 3704 C CD1 . LEU A 1 463 ? 27.892 87.850 10.828 1.00 27.12 ? 463 LEU A CD1 1 ATOM 3705 C CD2 . LEU A 1 463 ? 29.496 86.801 9.280 1.00 25.89 ? 463 LEU A CD2 1 ATOM 3706 N N . ASN A 1 464 ? 29.792 83.457 13.480 1.00 23.99 ? 464 ASN A N 1 ATOM 3707 C CA . ASN A 1 464 ? 30.315 82.817 14.700 1.00 23.97 ? 464 ASN A CA 1 ATOM 3708 C C . ASN A 1 464 ? 31.114 81.551 14.426 1.00 22.94 ? 464 ASN A C 1 ATOM 3709 O O . ASN A 1 464 ? 32.026 81.216 15.165 1.00 23.20 ? 464 ASN A O 1 ATOM 3710 C CB . ASN A 1 464 ? 29.175 82.547 15.695 1.00 23.84 ? 464 ASN A CB 1 ATOM 3711 C CG . ASN A 1 464 ? 28.582 83.819 16.230 1.00 25.72 ? 464 ASN A CG 1 ATOM 3712 O OD1 . ASN A 1 464 ? 27.369 83.984 16.252 1.00 30.88 ? 464 ASN A OD1 1 ATOM 3713 N ND2 . ASN A 1 464 ? 29.437 84.745 16.633 1.00 24.56 ? 464 ASN A ND2 1 ATOM 3714 N N . ASN A 1 465 ? 30.764 80.873 13.340 1.00 22.87 ? 465 ASN A N 1 ATOM 3715 C CA . ASN A 1 465 ? 31.334 79.586 12.959 1.00 23.93 ? 465 ASN A CA 1 ATOM 3716 C C . ASN A 1 465 ? 31.669 79.589 11.456 1.00 23.72 ? 465 ASN A C 1 ATOM 3717 O O . ASN A 1 465 ? 30.899 79.057 10.653 1.00 24.52 ? 465 ASN A O 1 ATOM 3718 C CB . ASN A 1 465 ? 30.375 78.438 13.323 1.00 23.52 ? 465 ASN A CB 1 ATOM 3719 C CG . ASN A 1 465 ? 29.972 78.469 14.782 1.00 24.77 ? 465 ASN A CG 1 ATOM 3720 O OD1 . ASN A 1 465 ? 30.637 77.880 15.629 1.00 24.42 ? 465 ASN A OD1 1 ATOM 3721 N ND2 . ASN A 1 465 ? 28.903 79.197 15.091 1.00 26.88 ? 465 ASN A ND2 1 ATOM 3722 N N . PRO A 1 466 ? 32.780 80.258 11.073 1.00 23.24 ? 466 PRO A N 1 ATOM 3723 C CA . PRO A 1 466 ? 33.093 80.534 9.650 1.00 22.99 ? 466 PRO A CA 1 ATOM 3724 C C . PRO A 1 466 ? 33.698 79.316 8.920 1.00 22.37 ? 466 PRO A C 1 ATOM 3725 O O . PRO A 1 466 ? 34.159 78.369 9.571 1.00 22.13 ? 466 PRO A O 1 ATOM 3726 C CB . PRO A 1 466 ? 34.154 81.672 9.760 1.00 22.48 ? 466 PRO A CB 1 ATOM 3727 C CG . PRO A 1 466 ? 34.927 81.287 10.989 1.00 22.33 ? 466 PRO A CG 1 ATOM 3728 C CD . PRO A 1 466 ? 33.795 80.871 11.963 1.00 23.42 ? 466 PRO A CD 1 ATOM 3729 N N . PRO A 1 467 ? 33.691 79.319 7.572 1.00 22.48 ? 467 PRO A N 1 ATOM 3730 C CA . PRO A 1 467 ? 34.277 78.144 6.879 1.00 22.75 ? 467 PRO A CA 1 ATOM 3731 C C . PRO A 1 467 ? 35.724 77.818 7.308 1.00 22.42 ? 467 PRO A C 1 ATOM 3732 O O . PRO A 1 467 ? 36.098 76.638 7.366 1.00 23.32 ? 467 PRO A O 1 ATOM 3733 C CB . PRO A 1 467 ? 34.236 78.553 5.405 1.00 23.05 ? 467 PRO A CB 1 ATOM 3734 C CG . PRO A 1 467 ? 33.146 79.616 5.326 1.00 23.38 ? 467 PRO A CG 1 ATOM 3735 C CD . PRO A 1 467 ? 33.113 80.304 6.639 1.00 22.22 ? 467 PRO A CD 1 ATOM 3736 N N . PHE A 1 468 ? 36.526 78.848 7.588 1.00 22.05 ? 468 PHE A N 1 ATOM 3737 C CA . PHE A 1 468 ? 37.969 78.703 7.943 1.00 21.35 ? 468 PHE A CA 1 ATOM 3738 C C . PHE A 1 468 ? 38.244 79.631 9.111 1.00 21.32 ? 468 PHE A C 1 ATOM 3739 O O . PHE A 1 468 ? 37.880 80.815 9.075 1.00 20.71 ? 468 PHE A O 1 ATOM 3740 C CB . PHE A 1 468 ? 38.908 79.070 6.785 1.00 21.26 ? 468 PHE A CB 1 ATOM 3741 C CG . PHE A 1 468 ? 40.384 79.068 7.165 1.00 21.03 ? 468 PHE A CG 1 ATOM 3742 C CD1 . PHE A 1 468 ? 41.101 77.871 7.223 1.00 20.20 ? 468 PHE A CD1 1 ATOM 3743 C CD2 . PHE A 1 468 ? 41.024 80.252 7.549 1.00 19.49 ? 468 PHE A CD2 1 ATOM 3744 C CE1 . PHE A 1 468 ? 42.474 77.860 7.609 1.00 22.88 ? 468 PHE A CE1 1 ATOM 3745 C CE2 . PHE A 1 468 ? 42.380 80.273 7.913 1.00 18.01 ? 468 PHE A CE2 1 ATOM 3746 C CZ . PHE A 1 468 ? 43.115 79.071 7.947 1.00 21.28 ? 468 PHE A CZ 1 ATOM 3747 N N . THR A 1 469 ? 38.854 79.088 10.152 1.00 21.13 ? 469 THR A N 1 ATOM 3748 C CA . THR A 1 469 ? 39.215 79.875 11.301 1.00 22.37 ? 469 THR A CA 1 ATOM 3749 C C . THR A 1 469 ? 40.736 79.861 11.385 1.00 22.10 ? 469 THR A C 1 ATOM 3750 O O . THR A 1 469 ? 41.362 78.775 11.440 1.00 22.03 ? 469 THR A O 1 ATOM 3751 C CB . THR A 1 469 ? 38.650 79.284 12.606 1.00 23.01 ? 469 THR A CB 1 ATOM 3752 O OG1 . THR A 1 469 ? 37.294 78.889 12.413 1.00 23.27 ? 469 THR A OG1 1 ATOM 3753 C CG2 . THR A 1 469 ? 38.742 80.293 13.781 1.00 23.00 ? 469 THR A CG2 1 ATOM 3754 N N . PRO A 1 470 ? 41.342 81.055 11.406 1.00 22.14 ? 470 PRO A N 1 ATOM 3755 C CA . PRO A 1 470 ? 42.816 81.100 11.631 1.00 22.22 ? 470 PRO A CA 1 ATOM 3756 C C . PRO A 1 470 ? 43.151 80.450 12.989 1.00 23.09 ? 470 PRO A C 1 ATOM 3757 O O . PRO A 1 470 ? 42.235 80.239 13.799 1.00 23.25 ? 470 PRO A O 1 ATOM 3758 C CB . PRO A 1 470 ? 43.133 82.591 11.634 1.00 21.93 ? 470 PRO A CB 1 ATOM 3759 C CG . PRO A 1 470 ? 41.954 83.259 10.932 1.00 22.02 ? 470 PRO A CG 1 ATOM 3760 C CD . PRO A 1 470 ? 40.744 82.395 11.263 1.00 21.46 ? 470 PRO A CD 1 ATOM 3761 N N . ARG A 1 471 ? 44.419 80.140 13.254 1.00 23.08 ? 471 ARG A N 1 ATOM 3762 C CA . ARG A 1 471 ? 44.786 79.388 14.458 1.00 24.63 ? 471 ARG A CA 1 ATOM 3763 C C . ARG A 1 471 ? 44.870 80.252 15.710 1.00 24.01 ? 471 ARG A C 1 ATOM 3764 O O . ARG A 1 471 ? 45.885 80.248 16.407 1.00 24.55 ? 471 ARG A O 1 ATOM 3765 C CB . ARG A 1 471 ? 46.098 78.643 14.241 1.00 24.38 ? 471 ARG A CB 1 ATOM 3766 C CG . ARG A 1 471 ? 47.293 79.526 13.908 1.00 27.14 ? 471 ARG A CG 1 ATOM 3767 C CD . ARG A 1 471 ? 48.573 78.670 13.787 1.00 28.81 ? 471 ARG A CD 1 ATOM 3768 N NE . ARG A 1 471 ? 48.460 77.669 12.714 1.00 32.39 ? 471 ARG A NE 1 ATOM 3769 C CZ . ARG A 1 471 ? 49.368 76.720 12.476 1.00 36.65 ? 471 ARG A CZ 1 ATOM 3770 N NH1 . ARG A 1 471 ? 50.481 76.649 13.235 1.00 35.35 ? 471 ARG A NH1 1 ATOM 3771 N NH2 . ARG A 1 471 ? 49.164 75.853 11.477 1.00 34.74 ? 471 ARG A NH2 1 ATOM 3772 N N . ILE A 1 472 ? 43.803 81.012 15.965 1.00 23.71 ? 472 ILE A N 1 ATOM 3773 C CA . ILE A 1 472 ? 43.655 81.845 17.148 1.00 23.77 ? 472 ILE A CA 1 ATOM 3774 C C . ILE A 1 472 ? 43.472 80.969 18.389 1.00 24.64 ? 472 ILE A C 1 ATOM 3775 O O . ILE A 1 472 ? 42.900 79.860 18.303 1.00 24.47 ? 472 ILE A O 1 ATOM 3776 C CB . ILE A 1 472 ? 42.408 82.769 17.016 1.00 24.06 ? 472 ILE A CB 1 ATOM 3777 C CG1 . ILE A 1 472 ? 41.136 81.923 16.861 1.00 23.87 ? 472 ILE A CG1 1 ATOM 3778 C CG2 . ILE A 1 472 ? 42.566 83.748 15.834 1.00 22.32 ? 472 ILE A CG2 1 ATOM 3779 C CD1 . ILE A 1 472 ? 39.874 82.699 17.151 1.00 25.72 ? 472 ILE A CD1 1 ATOM 3780 N N . LEU A 1 473 ? 43.951 81.464 19.538 1.00 24.23 ? 473 LEU A N 1 ATOM 3781 C CA . LEU A 1 473 ? 43.770 80.776 20.816 1.00 23.95 ? 473 LEU A CA 1 ATOM 3782 C C . LEU A 1 473 ? 42.345 80.266 21.012 1.00 24.50 ? 473 LEU A C 1 ATOM 3783 O O . LEU A 1 473 ? 41.381 81.042 20.880 1.00 24.30 ? 473 LEU A O 1 ATOM 3784 C CB . LEU A 1 473 ? 44.166 81.687 21.979 1.00 23.84 ? 473 LEU A CB 1 ATOM 3785 C CG . LEU A 1 473 ? 44.234 81.011 23.362 1.00 24.70 ? 473 LEU A CG 1 ATOM 3786 C CD1 . LEU A 1 473 ? 45.166 79.788 23.369 1.00 23.33 ? 473 LEU A CD1 1 ATOM 3787 C CD2 . LEU A 1 473 ? 44.636 81.987 24.445 1.00 23.53 ? 473 LEU A CD2 1 ATOM 3788 N N . ASP A 1 474 ? 42.234 78.953 21.281 1.00 25.41 ? 474 ASP A N 1 ATOM 3789 C CA . ASP A 1 474 ? 40.965 78.236 21.592 1.00 26.74 ? 474 ASP A CA 1 ATOM 3790 C C . ASP A 1 474 ? 40.066 77.949 20.389 1.00 26.62 ? 474 ASP A C 1 ATOM 3791 O O . ASP A 1 474 ? 39.036 77.268 20.527 1.00 27.43 ? 474 ASP A O 1 ATOM 3792 C CB . ASP A 1 474 ? 40.156 78.913 22.723 1.00 27.17 ? 474 ASP A CB 1 ATOM 3793 C CG . ASP A 1 474 ? 40.952 79.063 24.015 1.00 29.63 ? 474 ASP A CG 1 ATOM 3794 O OD1 . ASP A 1 474 ? 41.631 78.096 24.435 1.00 32.56 ? 474 ASP A OD1 1 ATOM 3795 O OD2 . ASP A 1 474 ? 40.882 80.158 24.630 1.00 32.60 ? 474 ASP A OD2 1 ATOM 3796 N N . GLY A 1 475 ? 40.438 78.446 19.212 1.00 25.60 ? 475 GLY A N 1 ATOM 3797 C CA . GLY A 1 475 ? 39.815 77.958 17.993 1.00 25.44 ? 475 GLY A CA 1 ATOM 3798 C C . GLY A 1 475 ? 38.409 78.450 17.672 1.00 25.22 ? 475 GLY A C 1 ATOM 3799 O O . GLY A 1 475 ? 37.848 78.027 16.691 1.00 26.08 ? 475 GLY A O 1 ATOM 3800 N N . TYR A 1 476 ? 37.849 79.359 18.463 1.00 24.72 ? 476 TYR A N 1 ATOM 3801 C CA . TYR A 1 476 ? 36.582 79.992 18.107 1.00 24.50 ? 476 TYR A CA 1 ATOM 3802 C C . TYR A 1 476 ? 36.759 81.474 18.231 1.00 22.99 ? 476 TYR A C 1 ATOM 3803 O O . TYR A 1 476 ? 37.252 81.934 19.240 1.00 23.16 ? 476 TYR A O 1 ATOM 3804 C CB . TYR A 1 476 ? 35.422 79.592 19.033 1.00 26.28 ? 476 TYR A CB 1 ATOM 3805 C CG . TYR A 1 476 ? 35.100 78.129 19.068 1.00 29.53 ? 476 TYR A CG 1 ATOM 3806 C CD1 . TYR A 1 476 ? 34.100 77.582 18.250 1.00 30.97 ? 476 TYR A CD1 1 ATOM 3807 C CD2 . TYR A 1 476 ? 35.786 77.282 19.938 1.00 32.29 ? 476 TYR A CD2 1 ATOM 3808 C CE1 . TYR A 1 476 ? 33.830 76.212 18.288 1.00 32.55 ? 476 TYR A CE1 1 ATOM 3809 C CE2 . TYR A 1 476 ? 35.526 75.915 19.974 1.00 32.86 ? 476 TYR A CE2 1 ATOM 3810 C CZ . TYR A 1 476 ? 34.562 75.398 19.163 1.00 31.75 ? 476 TYR A CZ 1 ATOM 3811 O OH . TYR A 1 476 ? 34.341 74.058 19.259 1.00 33.13 ? 476 TYR A OH 1 ATOM 3812 N N . LEU A 1 477 ? 36.275 82.216 17.242 1.00 21.61 ? 477 LEU A N 1 ATOM 3813 C CA . LEU A 1 477 ? 36.352 83.673 17.226 1.00 20.31 ? 477 LEU A CA 1 ATOM 3814 C C . LEU A 1 477 ? 35.723 84.339 18.442 1.00 20.38 ? 477 LEU A C 1 ATOM 3815 O O . LEU A 1 477 ? 36.247 85.337 18.932 1.00 19.20 ? 477 LEU A O 1 ATOM 3816 C CB . LEU A 1 477 ? 35.735 84.234 15.947 1.00 20.14 ? 477 LEU A CB 1 ATOM 3817 C CG . LEU A 1 477 ? 36.305 83.864 14.571 1.00 21.40 ? 477 LEU A CG 1 ATOM 3818 C CD1 . LEU A 1 477 ? 35.391 84.393 13.463 1.00 16.96 ? 477 LEU A CD1 1 ATOM 3819 C CD2 . LEU A 1 477 ? 37.694 84.490 14.397 1.00 21.55 ? 477 LEU A CD2 1 ATOM 3820 N N . PHE A 1 478 ? 34.610 83.801 18.949 1.00 20.02 ? 478 PHE A N 1 ATOM 3821 C CA . PHE A 1 478 ? 33.907 84.485 20.056 1.00 20.63 ? 478 PHE A CA 1 ATOM 3822 C C . PHE A 1 478 ? 34.416 84.131 21.448 1.00 21.01 ? 478 PHE A C 1 ATOM 3823 O O . PHE A 1 478 ? 33.848 84.588 22.437 1.00 20.52 ? 478 PHE A O 1 ATOM 3824 C CB . PHE A 1 478 ? 32.407 84.202 19.972 1.00 21.56 ? 478 PHE A CB 1 ATOM 3825 C CG . PHE A 1 478 ? 32.081 82.747 19.907 1.00 20.23 ? 478 PHE A CG 1 ATOM 3826 C CD1 . PHE A 1 478 ? 31.958 81.997 21.074 1.00 23.78 ? 478 PHE A CD1 1 ATOM 3827 C CD2 . PHE A 1 478 ? 31.912 82.129 18.682 1.00 19.43 ? 478 PHE A CD2 1 ATOM 3828 C CE1 . PHE A 1 478 ? 31.639 80.618 21.023 1.00 25.82 ? 478 PHE A CE1 1 ATOM 3829 C CE2 . PHE A 1 478 ? 31.605 80.774 18.597 1.00 23.27 ? 478 PHE A CE2 1 ATOM 3830 C CZ . PHE A 1 478 ? 31.458 80.007 19.765 1.00 24.01 ? 478 PHE A CZ 1 ATOM 3831 N N . CYS A 1 479 ? 35.460 83.297 21.519 1.00 22.00 ? 479 CYS A N 1 ATOM 3832 C CA A CYS A 1 479 ? 36.068 82.908 22.786 0.50 22.36 ? 479 CYS A CA 1 ATOM 3833 C CA B CYS A 1 479 ? 36.080 82.937 22.792 0.50 22.40 ? 479 CYS A CA 1 ATOM 3834 C C . CYS A 1 479 ? 36.560 84.149 23.536 1.00 22.45 ? 479 CYS A C 1 ATOM 3835 O O . CYS A 1 479 ? 37.381 84.898 23.025 1.00 21.44 ? 479 CYS A O 1 ATOM 3836 C CB A CYS A 1 479 ? 37.203 81.910 22.550 0.50 22.65 ? 479 CYS A CB 1 ATOM 3837 C CB B CYS A 1 479 ? 37.261 82.020 22.581 0.50 22.75 ? 479 CYS A CB 1 ATOM 3838 S SG A CYS A 1 479 ? 38.025 81.294 24.030 0.50 24.17 ? 479 CYS A SG 1 ATOM 3839 S SG B CYS A 1 479 ? 36.736 80.391 22.359 0.50 24.37 ? 479 CYS A SG 1 ATOM 3840 N N . LYS A 1 480 ? 36.019 84.326 24.742 1.00 22.70 ? 480 LYS A N 1 ATOM 3841 C CA . LYS A 1 480 ? 36.327 85.414 25.662 1.00 22.00 ? 480 LYS A CA 1 ATOM 3842 C C . LYS A 1 480 ? 36.192 86.792 25.027 1.00 22.16 ? 480 LYS A C 1 ATOM 3843 O O . LYS A 1 480 ? 36.949 87.730 25.375 1.00 21.94 ? 480 LYS A O 1 ATOM 3844 C CB . LYS A 1 480 ? 37.700 85.210 26.335 1.00 22.62 ? 480 LYS A CB 1 ATOM 3845 C CG . LYS A 1 480 ? 37.870 83.862 27.066 1.00 23.56 ? 480 LYS A CG 1 ATOM 3846 C CD . LYS A 1 480 ? 36.799 83.575 28.096 1.00 26.29 ? 480 LYS A CD 1 ATOM 3847 C CE . LYS A 1 480 ? 37.049 82.221 28.808 1.00 28.55 ? 480 LYS A CE 1 ATOM 3848 N NZ . LYS A 1 480 ? 35.830 81.299 28.670 1.00 28.05 ? 480 LYS A NZ 1 ATOM 3849 N N . THR A 1 481 ? 35.219 86.931 24.127 1.00 21.18 ? 481 THR A N 1 ATOM 3850 C CA . THR A 1 481 ? 34.883 88.247 23.565 1.00 20.59 ? 481 THR A CA 1 ATOM 3851 C C . THR A 1 481 ? 33.424 88.273 23.156 1.00 21.18 ? 481 THR A C 1 ATOM 3852 O O . THR A 1 481 ? 32.643 87.496 23.685 1.00 20.59 ? 481 THR A O 1 ATOM 3853 C CB . THR A 1 481 ? 35.832 88.652 22.364 1.00 21.60 ? 481 THR A CB 1 ATOM 3854 O OG1 . THR A 1 481 ? 35.549 89.995 21.962 1.00 17.70 ? 481 THR A OG1 1 ATOM 3855 C CG2 . THR A 1 481 ? 35.695 87.695 21.147 1.00 21.31 ? 481 THR A CG2 1 ATOM 3856 N N . LEU A 1 482 ? 33.041 89.151 22.228 1.00 21.82 ? 482 LEU A N 1 ATOM 3857 C CA . LEU A 1 482 ? 31.623 89.334 21.860 1.00 22.48 ? 482 LEU A CA 1 ATOM 3858 C C . LEU A 1 482 ? 31.254 88.395 20.716 1.00 23.08 ? 482 LEU A C 1 ATOM 3859 O O . LEU A 1 482 ? 32.140 87.894 20.009 1.00 22.26 ? 482 LEU A O 1 ATOM 3860 C CB . LEU A 1 482 ? 31.315 90.800 21.482 1.00 22.33 ? 482 LEU A CB 1 ATOM 3861 C CG . LEU A 1 482 ? 31.689 91.929 22.458 1.00 23.90 ? 482 LEU A CG 1 ATOM 3862 C CD1 . LEU A 1 482 ? 31.029 93.276 22.028 1.00 26.47 ? 482 LEU A CD1 1 ATOM 3863 C CD2 . LEU A 1 482 ? 31.322 91.583 23.902 1.00 23.09 ? 482 LEU A CD2 1 ATOM 3864 N N . CYS A 1 483 ? 29.944 88.147 20.549 1.00 22.67 ? 483 CYS A N 1 ATOM 3865 C CA . CYS A 1 483 ? 29.419 87.412 19.392 1.00 22.85 ? 483 CYS A CA 1 ATOM 3866 C C . CYS A 1 483 ? 29.864 88.129 18.127 1.00 22.03 ? 483 CYS A C 1 ATOM 3867 O O . CYS A 1 483 ? 29.874 89.353 18.097 1.00 20.52 ? 483 CYS A O 1 ATOM 3868 C CB . CYS A 1 483 ? 27.881 87.400 19.435 1.00 23.42 ? 483 CYS A CB 1 ATOM 3869 S SG . CYS A 1 483 ? 27.311 86.423 20.799 1.00 29.04 ? 483 CYS A SG 1 ATOM 3870 N N . MET A 1 484 ? 30.211 87.355 17.098 1.00 21.61 ? 484 MET A N 1 ATOM 3871 C CA . MET A 1 484 ? 30.633 87.885 15.807 1.00 21.25 ? 484 MET A CA 1 ATOM 3872 C C . MET A 1 484 ? 29.479 88.537 15.055 1.00 22.21 ? 484 MET A C 1 ATOM 3873 O O . MET A 1 484 ? 29.700 89.388 14.174 1.00 21.10 ? 484 MET A O 1 ATOM 3874 C CB . MET A 1 484 ? 31.331 86.820 14.964 1.00 21.07 ? 484 MET A CB 1 ATOM 3875 C CG . MET A 1 484 ? 32.644 86.314 15.561 1.00 19.51 ? 484 MET A CG 1 ATOM 3876 S SD . MET A 1 484 ? 33.903 87.668 15.596 1.00 22.34 ? 484 MET A SD 1 ATOM 3877 C CE . MET A 1 484 ? 34.108 87.968 17.340 1.00 18.59 ? 484 MET A CE 1 ATOM 3878 N N . ASP A 1 485 ? 28.247 88.191 15.434 1.00 22.21 ? 485 ASP A N 1 ATOM 3879 C CA . ASP A 1 485 ? 27.091 88.844 14.828 1.00 23.29 ? 485 ASP A CA 1 ATOM 3880 C C . ASP A 1 485 ? 26.557 89.996 15.679 1.00 23.55 ? 485 ASP A C 1 ATOM 3881 O O . ASP A 1 485 ? 25.473 90.531 15.406 1.00 23.79 ? 485 ASP A O 1 ATOM 3882 C CB . ASP A 1 485 ? 25.988 87.848 14.431 1.00 24.21 ? 485 ASP A CB 1 ATOM 3883 C CG . ASP A 1 485 ? 25.562 86.882 15.578 1.00 27.16 ? 485 ASP A CG 1 ATOM 3884 O OD1 . ASP A 1 485 ? 25.986 86.984 16.764 1.00 27.11 ? 485 ASP A OD1 1 ATOM 3885 O OD2 . ASP A 1 485 ? 24.776 85.980 15.240 1.00 31.37 ? 485 ASP A OD2 1 ATOM 3886 N N . ALA A 1 486 ? 27.322 90.381 16.703 1.00 22.52 ? 486 ALA A N 1 ATOM 3887 C CA . ALA A 1 486 ? 27.020 91.593 17.421 1.00 22.78 ? 486 ALA A CA 1 ATOM 3888 C C . ALA A 1 486 ? 27.209 92.777 16.476 1.00 24.12 ? 486 ALA A C 1 ATOM 3889 O O . ALA A 1 486 ? 27.954 92.712 15.479 1.00 23.70 ? 486 ALA A O 1 ATOM 3890 C CB . ALA A 1 486 ? 27.856 91.716 18.636 1.00 22.80 ? 486 ALA A CB 1 ATOM 3891 N N . VAL A 1 487 ? 26.493 93.854 16.769 1.00 24.40 ? 487 VAL A N 1 ATOM 3892 C CA . VAL A 1 487 ? 26.303 94.895 15.804 1.00 24.80 ? 487 VAL A CA 1 ATOM 3893 C C . VAL A 1 487 ? 26.679 96.293 16.371 1.00 24.44 ? 487 VAL A C 1 ATOM 3894 O O . VAL A 1 487 ? 26.277 96.659 17.450 1.00 23.16 ? 487 VAL A O 1 ATOM 3895 C CB . VAL A 1 487 ? 24.858 94.742 15.248 1.00 26.35 ? 487 VAL A CB 1 ATOM 3896 C CG1 . VAL A 1 487 ? 24.038 95.987 15.392 1.00 25.96 ? 487 VAL A CG1 1 ATOM 3897 C CG2 . VAL A 1 487 ? 24.877 94.160 13.836 1.00 26.17 ? 487 VAL A CG2 1 ATOM 3898 N N . GLN A 1 488 ? 27.521 97.027 15.640 1.00 24.88 ? 488 GLN A N 1 ATOM 3899 C CA . GLN A 1 488 ? 27.945 98.356 15.993 1.00 25.02 ? 488 GLN A CA 1 ATOM 3900 C C . GLN A 1 488 ? 27.706 99.343 14.825 1.00 26.06 ? 488 GLN A C 1 ATOM 3901 O O . GLN A 1 488 ? 27.319 98.974 13.714 1.00 25.92 ? 488 GLN A O 1 ATOM 3902 C CB . GLN A 1 488 ? 29.426 98.326 16.398 1.00 26.26 ? 488 GLN A CB 1 ATOM 3903 C CG . GLN A 1 488 ? 29.699 97.678 17.767 1.00 24.99 ? 488 GLN A CG 1 ATOM 3904 C CD . GLN A 1 488 ? 31.204 97.640 18.160 1.00 25.77 ? 488 GLN A CD 1 ATOM 3905 O OE1 . GLN A 1 488 ? 31.800 98.669 18.543 1.00 28.07 ? 488 GLN A OE1 1 ATOM 3906 N NE2 . GLN A 1 488 ? 31.790 96.458 18.111 1.00 22.92 ? 488 GLN A NE2 1 ATOM 3907 N N . HIS A 1 489 ? 27.920 100.614 15.093 1.00 26.83 ? 489 HIS A N 1 ATOM 3908 C CA . HIS A 1 489 ? 27.742 101.634 14.093 1.00 28.37 ? 489 HIS A CA 1 ATOM 3909 C C . HIS A 1 489 ? 28.648 101.388 12.860 1.00 27.91 ? 489 HIS A C 1 ATOM 3910 O O . HIS A 1 489 ? 28.172 101.497 11.739 1.00 28.38 ? 489 HIS A O 1 ATOM 3911 C CB . HIS A 1 489 ? 27.930 103.001 14.740 1.00 28.84 ? 489 HIS A CB 1 ATOM 3912 C CG . HIS A 1 489 ? 27.663 104.153 13.829 1.00 32.53 ? 489 HIS A CG 1 ATOM 3913 N ND1 . HIS A 1 489 ? 28.676 104.851 13.198 1.00 36.08 ? 489 HIS A ND1 1 ATOM 3914 C CD2 . HIS A 1 489 ? 26.505 104.760 13.472 1.00 37.35 ? 489 HIS A CD2 1 ATOM 3915 C CE1 . HIS A 1 489 ? 28.152 105.825 12.471 1.00 39.07 ? 489 HIS A CE1 1 ATOM 3916 N NE2 . HIS A 1 489 ? 26.836 105.796 12.625 1.00 41.28 ? 489 HIS A NE2 1 ATOM 3917 N N . TRP A 1 490 ? 29.918 101.004 13.058 1.00 27.13 ? 490 TRP A N 1 ATOM 3918 C CA . TRP A 1 490 ? 30.792 100.668 11.919 1.00 25.95 ? 490 TRP A CA 1 ATOM 3919 C C . TRP A 1 490 ? 30.530 99.336 11.229 1.00 26.02 ? 490 TRP A C 1 ATOM 3920 O O . TRP A 1 490 ? 31.074 99.089 10.151 1.00 25.92 ? 490 TRP A O 1 ATOM 3921 C CB . TRP A 1 490 ? 32.270 100.736 12.289 1.00 25.37 ? 490 TRP A CB 1 ATOM 3922 C CG . TRP A 1 490 ? 32.819 102.106 12.468 1.00 24.65 ? 490 TRP A CG 1 ATOM 3923 C CD1 . TRP A 1 490 ? 32.225 103.301 12.140 1.00 24.96 ? 490 TRP A CD1 1 ATOM 3924 C CD2 . TRP A 1 490 ? 34.115 102.435 13.008 1.00 24.10 ? 490 TRP A CD2 1 ATOM 3925 N NE1 . TRP A 1 490 ? 33.064 104.341 12.472 1.00 24.66 ? 490 TRP A NE1 1 ATOM 3926 C CE2 . TRP A 1 490 ? 34.221 103.834 13.014 1.00 23.46 ? 490 TRP A CE2 1 ATOM 3927 C CE3 . TRP A 1 490 ? 35.181 101.667 13.520 1.00 24.74 ? 490 TRP A CE3 1 ATOM 3928 C CZ2 . TRP A 1 490 ? 35.379 104.499 13.478 1.00 27.37 ? 490 TRP A CZ2 1 ATOM 3929 C CZ3 . TRP A 1 490 ? 36.312 102.321 13.998 1.00 24.87 ? 490 TRP A CZ3 1 ATOM 3930 C CH2 . TRP A 1 490 ? 36.405 103.724 13.966 1.00 25.00 ? 490 TRP A CH2 1 ATOM 3931 N N . GLY A 1 491 ? 29.740 98.464 11.865 1.00 25.93 ? 491 GLY A N 1 ATOM 3932 C CA . GLY A 1 491 ? 29.330 97.222 11.247 1.00 25.97 ? 491 GLY A CA 1 ATOM 3933 C C . GLY A 1 491 ? 29.298 96.080 12.231 1.00 25.81 ? 491 GLY A C 1 ATOM 3934 O O . GLY A 1 491 ? 29.173 96.287 13.421 1.00 25.42 ? 491 GLY A O 1 ATOM 3935 N N . LYS A 1 492 ? 29.411 94.869 11.716 1.00 26.11 ? 492 LYS A N 1 ATOM 3936 C CA . LYS A 1 492 ? 29.363 93.664 12.525 1.00 26.92 ? 492 LYS A CA 1 ATOM 3937 C C . LYS A 1 492 ? 30.692 93.385 13.205 1.00 26.12 ? 492 LYS A C 1 ATOM 3938 O O . LYS A 1 492 ? 31.760 93.650 12.657 1.00 25.77 ? 492 LYS A O 1 ATOM 3939 C CB . LYS A 1 492 ? 28.990 92.462 11.646 1.00 28.19 ? 492 LYS A CB 1 ATOM 3940 C CG . LYS A 1 492 ? 27.754 92.695 10.842 1.00 33.72 ? 492 LYS A CG 1 ATOM 3941 C CD . LYS A 1 492 ? 26.964 91.415 10.539 1.00 41.47 ? 492 LYS A CD 1 ATOM 3942 C CE . LYS A 1 492 ? 25.487 91.583 11.014 1.00 44.93 ? 492 LYS A CE 1 ATOM 3943 N NZ . LYS A 1 492 ? 25.223 91.056 12.417 1.00 44.76 ? 492 LYS A NZ 1 ATOM 3944 N N . GLN A 1 493 ? 30.604 92.807 14.394 1.00 24.94 ? 493 GLN A N 1 ATOM 3945 C CA . GLN A 1 493 ? 31.756 92.397 15.181 1.00 23.78 ? 493 GLN A CA 1 ATOM 3946 C C . GLN A 1 493 ? 32.740 91.522 14.393 1.00 23.20 ? 493 GLN A C 1 ATOM 3947 O O . GLN A 1 493 ? 33.957 91.657 14.543 1.00 22.53 ? 493 GLN A O 1 ATOM 3948 C CB . GLN A 1 493 ? 31.255 91.678 16.437 1.00 24.15 ? 493 GLN A CB 1 ATOM 3949 C CG . GLN A 1 493 ? 32.301 91.211 17.423 1.00 25.44 ? 493 GLN A CG 1 ATOM 3950 C CD . GLN A 1 493 ? 33.002 92.349 18.166 1.00 27.63 ? 493 GLN A CD 1 ATOM 3951 O OE1 . GLN A 1 493 ? 32.611 93.514 18.078 1.00 27.06 ? 493 GLN A OE1 1 ATOM 3952 N NE2 . GLN A 1 493 ? 34.050 91.996 18.905 1.00 23.83 ? 493 GLN A NE2 1 ATOM 3953 N N . TYR A 1 494 ? 32.220 90.621 13.560 1.00 21.08 ? 494 TYR A N 1 ATOM 3954 C CA . TYR A 1 494 ? 33.049 89.845 12.635 1.00 20.43 ? 494 TYR A CA 1 ATOM 3955 C C . TYR A 1 494 ? 34.082 90.703 11.878 1.00 20.41 ? 494 TYR A C 1 ATOM 3956 O O . TYR A 1 494 ? 35.223 90.271 11.654 1.00 19.24 ? 494 TYR A O 1 ATOM 3957 C CB . TYR A 1 494 ? 32.140 89.182 11.616 1.00 19.53 ? 494 TYR A CB 1 ATOM 3958 C CG . TYR A 1 494 ? 32.820 88.179 10.726 1.00 19.77 ? 494 TYR A CG 1 ATOM 3959 C CD1 . TYR A 1 494 ? 33.055 86.872 11.180 1.00 18.18 ? 494 TYR A CD1 1 ATOM 3960 C CD2 . TYR A 1 494 ? 33.228 88.527 9.432 1.00 18.66 ? 494 TYR A CD2 1 ATOM 3961 C CE1 . TYR A 1 494 ? 33.657 85.932 10.363 1.00 20.34 ? 494 TYR A CE1 1 ATOM 3962 C CE2 . TYR A 1 494 ? 33.830 87.597 8.614 1.00 16.55 ? 494 TYR A CE2 1 ATOM 3963 C CZ . TYR A 1 494 ? 34.049 86.300 9.086 1.00 18.51 ? 494 TYR A CZ 1 ATOM 3964 O OH . TYR A 1 494 ? 34.639 85.350 8.280 1.00 17.90 ? 494 TYR A OH 1 ATOM 3965 N N . ASP A 1 495 ? 33.646 91.893 11.453 1.00 20.06 ? 495 ASP A N 1 ATOM 3966 C CA . ASP A 1 495 ? 34.461 92.780 10.615 1.00 20.35 ? 495 ASP A CA 1 ATOM 3967 C C . ASP A 1 495 ? 35.279 93.789 11.429 1.00 19.96 ? 495 ASP A C 1 ATOM 3968 O O . ASP A 1 495 ? 36.345 94.200 11.010 1.00 20.95 ? 495 ASP A O 1 ATOM 3969 C CB . ASP A 1 495 ? 33.550 93.576 9.675 1.00 19.73 ? 495 ASP A CB 1 ATOM 3970 C CG . ASP A 1 495 ? 33.012 92.746 8.532 1.00 20.52 ? 495 ASP A CG 1 ATOM 3971 O OD1 . ASP A 1 495 ? 33.682 91.786 8.053 1.00 22.09 ? 495 ASP A OD1 1 ATOM 3972 O OD2 . ASP A 1 495 ? 31.918 93.106 8.074 1.00 22.56 ? 495 ASP A OD2 1 ATOM 3973 N N . ILE A 1 496 ? 34.745 94.229 12.563 1.00 19.38 ? 496 ILE A N 1 ATOM 3974 C CA . ILE A 1 496 ? 35.333 95.336 13.304 1.00 19.71 ? 496 ILE A CA 1 ATOM 3975 C C . ILE A 1 496 ? 35.837 94.982 14.683 1.00 19.21 ? 496 ILE A C 1 ATOM 3976 O O . ILE A 1 496 ? 36.214 95.882 15.442 1.00 21.17 ? 496 ILE A O 1 ATOM 3977 C CB . ILE A 1 496 ? 34.356 96.540 13.480 1.00 18.96 ? 496 ILE A CB 1 ATOM 3978 C CG1 . ILE A 1 496 ? 33.332 96.240 14.569 1.00 19.53 ? 496 ILE A CG1 1 ATOM 3979 C CG2 . ILE A 1 496 ? 33.784 96.997 12.147 1.00 20.15 ? 496 ILE A CG2 1 ATOM 3980 C CD1 . ILE A 1 496 ? 32.278 97.272 14.662 1.00 19.45 ? 496 ILE A CD1 1 ATOM 3981 N N . HIS A 1 497 ? 35.839 93.702 15.030 1.00 18.74 ? 497 HIS A N 1 ATOM 3982 C CA . HIS A 1 497 ? 36.319 93.271 16.328 1.00 18.48 ? 497 HIS A CA 1 ATOM 3983 C C . HIS A 1 497 ? 37.733 93.866 16.645 1.00 19.57 ? 497 HIS A C 1 ATOM 3984 O O . HIS A 1 497 ? 37.981 94.341 17.766 1.00 21.19 ? 497 HIS A O 1 ATOM 3985 C CB . HIS A 1 497 ? 36.395 91.756 16.351 1.00 17.14 ? 497 HIS A CB 1 ATOM 3986 C CG . HIS A 1 497 ? 37.106 91.211 17.547 1.00 16.45 ? 497 HIS A CG 1 ATOM 3987 N ND1 . HIS A 1 497 ? 38.465 90.991 17.568 1.00 19.00 ? 497 HIS A ND1 1 ATOM 3988 C CD2 . HIS A 1 497 ? 36.652 90.846 18.762 1.00 13.76 ? 497 HIS A CD2 1 ATOM 3989 C CE1 . HIS A 1 497 ? 38.817 90.495 18.736 1.00 16.12 ? 497 HIS A CE1 1 ATOM 3990 N NE2 . HIS A 1 497 ? 37.737 90.425 19.489 1.00 20.87 ? 497 HIS A NE2 1 ATOM 3991 N N . ASN A 1 498 ? 38.634 93.835 15.667 1.00 19.57 ? 498 ASN A N 1 ATOM 3992 C CA . ASN A 1 498 ? 40.038 94.301 15.873 1.00 20.64 ? 498 ASN A CA 1 ATOM 3993 C C . ASN A 1 498 ? 40.163 95.815 16.018 1.00 21.01 ? 498 ASN A C 1 ATOM 3994 O O . ASN A 1 498 ? 41.217 96.336 16.364 1.00 22.90 ? 498 ASN A O 1 ATOM 3995 C CB . ASN A 1 498 ? 40.944 93.808 14.756 1.00 19.20 ? 498 ASN A CB 1 ATOM 3996 C CG . ASN A 1 498 ? 41.384 92.378 14.954 1.00 19.73 ? 498 ASN A CG 1 ATOM 3997 O OD1 . ASN A 1 498 ? 42.036 91.781 14.085 1.00 22.99 ? 498 ASN A OD1 1 ATOM 3998 N ND2 . ASN A 1 498 ? 41.027 91.814 16.077 1.00 17.38 ? 498 ASN A ND2 1 ATOM 3999 N N . LEU A 1 499 ? 39.052 96.501 15.793 1.00 21.37 ? 499 LEU A N 1 ATOM 4000 C CA . LEU A 1 499 ? 38.976 97.952 15.877 1.00 21.73 ? 499 LEU A CA 1 ATOM 4001 C C . LEU A 1 499 ? 38.356 98.479 17.188 1.00 21.66 ? 499 LEU A C 1 ATOM 4002 O O . LEU A 1 499 ? 38.189 99.678 17.328 1.00 21.89 ? 499 LEU A O 1 ATOM 4003 C CB . LEU A 1 499 ? 38.156 98.471 14.688 1.00 21.13 ? 499 LEU A CB 1 ATOM 4004 C CG . LEU A 1 499 ? 38.678 98.219 13.280 1.00 21.50 ? 499 LEU A CG 1 ATOM 4005 C CD1 . LEU A 1 499 ? 37.729 98.913 12.282 1.00 21.67 ? 499 LEU A CD1 1 ATOM 4006 C CD2 . LEU A 1 499 ? 40.058 98.805 13.178 1.00 19.87 ? 499 LEU A CD2 1 ATOM 4007 N N . TYR A 1 500 ? 38.011 97.599 18.134 1.00 21.57 ? 500 TYR A N 1 ATOM 4008 C CA . TYR A 1 500 ? 37.349 98.032 19.379 1.00 21.10 ? 500 TYR A CA 1 ATOM 4009 C C . TYR A 1 500 ? 38.286 98.932 20.221 1.00 20.70 ? 500 TYR A C 1 ATOM 4010 O O . TYR A 1 500 ? 37.928 100.062 20.546 1.00 21.14 ? 500 TYR A O 1 ATOM 4011 C CB . TYR A 1 500 ? 36.820 96.848 20.210 1.00 20.99 ? 500 TYR A CB 1 ATOM 4012 C CG . TYR A 1 500 ? 35.891 97.295 21.337 1.00 23.00 ? 500 TYR A CG 1 ATOM 4013 C CD1 . TYR A 1 500 ? 34.524 97.222 21.188 1.00 20.02 ? 500 TYR A CD1 1 ATOM 4014 C CD2 . TYR A 1 500 ? 36.399 97.826 22.538 1.00 20.73 ? 500 TYR A CD2 1 ATOM 4015 C CE1 . TYR A 1 500 ? 33.651 97.653 22.207 1.00 21.82 ? 500 TYR A CE1 1 ATOM 4016 C CE2 . TYR A 1 500 ? 35.564 98.238 23.541 1.00 21.60 ? 500 TYR A CE2 1 ATOM 4017 C CZ . TYR A 1 500 ? 34.166 98.146 23.368 1.00 22.35 ? 500 TYR A CZ 1 ATOM 4018 O OH . TYR A 1 500 ? 33.295 98.579 24.353 1.00 22.21 ? 500 TYR A OH 1 ATOM 4019 N N . GLY A 1 501 ? 39.484 98.440 20.543 1.00 20.28 ? 501 GLY A N 1 ATOM 4020 C CA . GLY A 1 501 ? 40.438 99.186 21.355 1.00 19.44 ? 501 GLY A CA 1 ATOM 4021 C C . GLY A 1 501 ? 40.889 100.454 20.673 1.00 18.72 ? 501 GLY A C 1 ATOM 4022 O O . GLY A 1 501 ? 41.105 101.478 21.317 1.00 19.64 ? 501 GLY A O 1 ATOM 4023 N N . TYR A 1 502 ? 40.988 100.390 19.355 1.00 18.75 ? 502 TYR A N 1 ATOM 4024 C CA . TYR A 1 502 ? 41.284 101.560 18.531 1.00 19.28 ? 502 TYR A CA 1 ATOM 4025 C C . TYR A 1 502 ? 40.145 102.620 18.642 1.00 19.41 ? 502 TYR A C 1 ATOM 4026 O O . TYR A 1 502 ? 40.395 103.820 18.877 1.00 18.37 ? 502 TYR A O 1 ATOM 4027 C CB . TYR A 1 502 ? 41.518 101.078 17.069 1.00 19.12 ? 502 TYR A CB 1 ATOM 4028 C CG . TYR A 1 502 ? 41.651 102.145 16.003 1.00 19.73 ? 502 TYR A CG 1 ATOM 4029 C CD1 . TYR A 1 502 ? 42.827 102.860 15.861 1.00 19.75 ? 502 TYR A CD1 1 ATOM 4030 C CD2 . TYR A 1 502 ? 40.605 102.404 15.111 1.00 19.19 ? 502 TYR A CD2 1 ATOM 4031 C CE1 . TYR A 1 502 ? 42.960 103.833 14.885 1.00 21.52 ? 502 TYR A CE1 1 ATOM 4032 C CE2 . TYR A 1 502 ? 40.721 103.370 14.114 1.00 21.09 ? 502 TYR A CE2 1 ATOM 4033 C CZ . TYR A 1 502 ? 41.904 104.083 14.020 1.00 21.64 ? 502 TYR A CZ 1 ATOM 4034 O OH . TYR A 1 502 ? 42.061 105.035 13.055 1.00 24.41 ? 502 TYR A OH 1 ATOM 4035 N N . SER A 1 503 ? 38.901 102.175 18.518 1.00 18.96 ? 503 SER A N 1 ATOM 4036 C CA . SER A 1 503 ? 37.762 103.101 18.547 1.00 20.21 ? 503 SER A CA 1 ATOM 4037 C C . SER A 1 503 ? 37.677 103.715 19.953 1.00 20.04 ? 503 SER A C 1 ATOM 4038 O O . SER A 1 503 ? 37.372 104.906 20.100 1.00 20.20 ? 503 SER A O 1 ATOM 4039 C CB . SER A 1 503 ? 36.451 102.377 18.128 1.00 20.13 ? 503 SER A CB 1 ATOM 4040 O OG . SER A 1 503 ? 36.086 101.409 19.105 1.00 22.92 ? 503 SER A OG 1 ATOM 4041 N N . MET A 1 504 ? 38.017 102.910 20.961 1.00 19.92 ? 504 MET A N 1 ATOM 4042 C CA . MET A 1 504 ? 38.008 103.325 22.355 1.00 20.23 ? 504 MET A CA 1 ATOM 4043 C C . MET A 1 504 ? 39.113 104.341 22.695 1.00 20.34 ? 504 MET A C 1 ATOM 4044 O O . MET A 1 504 ? 38.853 105.281 23.450 1.00 19.21 ? 504 MET A O 1 ATOM 4045 C CB . MET A 1 504 ? 38.052 102.107 23.298 1.00 20.02 ? 504 MET A CB 1 ATOM 4046 C CG . MET A 1 504 ? 37.751 102.430 24.766 1.00 20.20 ? 504 MET A CG 1 ATOM 4047 S SD . MET A 1 504 ? 38.140 101.092 25.884 1.00 22.07 ? 504 MET A SD 1 ATOM 4048 C CE . MET A 1 504 ? 37.786 101.804 27.486 1.00 20.58 ? 504 MET A CE 1 ATOM 4049 N N . ALA A 1 505 ? 40.328 104.172 22.145 1.00 20.08 ? 505 ALA A N 1 ATOM 4050 C CA . ALA A 1 505 ? 41.380 105.189 22.299 1.00 19.95 ? 505 ALA A CA 1 ATOM 4051 C C . ALA A 1 505 ? 41.005 106.500 21.619 1.00 19.90 ? 505 ALA A C 1 ATOM 4052 O O . ALA A 1 505 ? 41.325 107.562 22.147 1.00 19.11 ? 505 ALA A O 1 ATOM 4053 C CB . ALA A 1 505 ? 42.717 104.705 21.763 1.00 19.95 ? 505 ALA A CB 1 ATOM 4054 N N . VAL A 1 506 ? 40.366 106.422 20.442 1.00 20.22 ? 506 VAL A N 1 ATOM 4055 C CA . VAL A 1 506 ? 39.898 107.626 19.731 1.00 20.79 ? 506 VAL A CA 1 ATOM 4056 C C . VAL A 1 506 ? 38.906 108.413 20.614 1.00 21.49 ? 506 VAL A C 1 ATOM 4057 O O . VAL A 1 506 ? 39.114 109.621 20.866 1.00 21.71 ? 506 VAL A O 1 ATOM 4058 C CB . VAL A 1 506 ? 39.307 107.285 18.339 1.00 21.15 ? 506 VAL A CB 1 ATOM 4059 C CG1 . VAL A 1 506 ? 38.672 108.521 17.667 1.00 20.65 ? 506 VAL A CG1 1 ATOM 4060 C CG2 . VAL A 1 506 ? 40.396 106.693 17.411 1.00 20.92 ? 506 VAL A CG2 1 ATOM 4061 N N . ALA A 1 507 ? 37.865 107.718 21.116 1.00 22.20 ? 507 ALA A N 1 ATOM 4062 C CA . ALA A 1 507 ? 36.830 108.308 21.990 1.00 21.92 ? 507 ALA A CA 1 ATOM 4063 C C . ALA A 1 507 ? 37.404 108.884 23.269 1.00 22.22 ? 507 ALA A C 1 ATOM 4064 O O . ALA A 1 507 ? 36.905 109.891 23.760 1.00 23.61 ? 507 ALA A O 1 ATOM 4065 C CB . ALA A 1 507 ? 35.743 107.270 22.338 1.00 22.30 ? 507 ALA A CB 1 ATOM 4066 N N . THR A 1 508 ? 38.424 108.218 23.817 1.00 21.91 ? 508 THR A N 1 ATOM 4067 C CA . THR A 1 508 ? 39.055 108.601 25.058 1.00 22.40 ? 508 THR A CA 1 ATOM 4068 C C . THR A 1 508 ? 39.893 109.852 24.858 1.00 23.35 ? 508 THR A C 1 ATOM 4069 O O . THR A 1 508 ? 39.868 110.751 25.710 1.00 22.69 ? 508 THR A O 1 ATOM 4070 C CB . THR A 1 508 ? 39.915 107.475 25.636 1.00 22.12 ? 508 THR A CB 1 ATOM 4071 O OG1 . THR A 1 508 ? 39.099 106.320 25.825 1.00 22.65 ? 508 THR A OG1 1 ATOM 4072 C CG2 . THR A 1 508 ? 40.504 107.888 26.978 1.00 21.83 ? 508 THR A CG2 1 ATOM 4073 N N . ALA A 1 509 ? 40.611 109.917 23.733 1.00 23.93 ? 509 ALA A N 1 ATOM 4074 C CA . ALA A 1 509 ? 41.258 111.158 23.319 1.00 25.89 ? 509 ALA A CA 1 ATOM 4075 C C . ALA A 1 509 ? 40.251 112.298 23.090 1.00 26.78 ? 509 ALA A C 1 ATOM 4076 O O . ALA A 1 509 ? 40.542 113.441 23.416 1.00 26.63 ? 509 ALA A O 1 ATOM 4077 C CB . ALA A 1 509 ? 42.140 110.951 22.094 1.00 25.56 ? 509 ALA A CB 1 ATOM 4078 N N . GLU A 1 510 ? 39.073 111.981 22.544 1.00 28.47 ? 510 GLU A N 1 ATOM 4079 C CA . GLU A 1 510 ? 37.979 112.962 22.449 1.00 29.72 ? 510 GLU A CA 1 ATOM 4080 C C . GLU A 1 510 ? 37.576 113.507 23.848 1.00 29.46 ? 510 GLU A C 1 ATOM 4081 O O . GLU A 1 510 ? 37.491 114.731 24.050 1.00 28.88 ? 510 GLU A O 1 ATOM 4082 C CB . GLU A 1 510 ? 36.794 112.348 21.684 1.00 30.57 ? 510 GLU A CB 1 ATOM 4083 C CG . GLU A 1 510 ? 35.743 113.323 21.152 1.00 35.68 ? 510 GLU A CG 1 ATOM 4084 C CD . GLU A 1 510 ? 36.278 114.338 20.101 1.00 42.09 ? 510 GLU A CD 1 ATOM 4085 O OE1 . GLU A 1 510 ? 37.428 114.159 19.603 1.00 43.33 ? 510 GLU A OE1 1 ATOM 4086 O OE2 . GLU A 1 510 ? 35.528 115.316 19.781 1.00 42.59 ? 510 GLU A OE2 1 ATOM 4087 N N . ALA A 1 511 ? 37.363 112.601 24.810 1.00 28.77 ? 511 ALA A N 1 ATOM 4088 C CA . ALA A 1 511 ? 37.039 112.966 26.194 1.00 27.82 ? 511 ALA A CA 1 ATOM 4089 C C . ALA A 1 511 ? 38.088 113.891 26.831 1.00 27.77 ? 511 ALA A C 1 ATOM 4090 O O . ALA A 1 511 ? 37.736 114.864 27.515 1.00 26.77 ? 511 ALA A O 1 ATOM 4091 C CB . ALA A 1 511 ? 36.847 111.712 27.039 1.00 28.26 ? 511 ALA A CB 1 ATOM 4092 N N . ALA A 1 512 ? 39.371 113.589 26.619 1.00 26.64 ? 512 ALA A N 1 ATOM 4093 C CA . ALA A 1 512 ? 40.466 114.478 27.064 1.00 26.86 ? 512 ALA A CA 1 ATOM 4094 C C . ALA A 1 512 ? 40.361 115.946 26.607 1.00 26.76 ? 512 ALA A C 1 ATOM 4095 O O . ALA A 1 512 ? 40.720 116.845 27.369 1.00 27.21 ? 512 ALA A O 1 ATOM 4096 C CB . ALA A 1 512 ? 41.878 113.884 26.699 1.00 26.33 ? 512 ALA A CB 1 ATOM 4097 N N . LYS A 1 513 ? 39.875 116.194 25.391 1.00 26.84 ? 513 LYS A N 1 ATOM 4098 C CA . LYS A 1 513 ? 39.572 117.571 24.928 1.00 28.53 ? 513 LYS A CA 1 ATOM 4099 C C . LYS A 1 513 ? 38.637 118.362 25.866 1.00 28.04 ? 513 LYS A C 1 ATOM 4100 O O . LYS A 1 513 ? 38.723 119.579 25.936 1.00 28.20 ? 513 LYS A O 1 ATOM 4101 C CB . LYS A 1 513 ? 38.950 117.596 23.506 1.00 28.27 ? 513 LYS A CB 1 ATOM 4102 C CG . LYS A 1 513 ? 39.722 116.867 22.412 1.00 29.75 ? 513 LYS A CG 1 ATOM 4103 C CD . LYS A 1 513 ? 39.100 117.079 21.042 1.00 30.15 ? 513 LYS A CD 1 ATOM 4104 C CE . LYS A 1 513 ? 39.905 116.364 19.954 1.00 34.63 ? 513 LYS A CE 1 ATOM 4105 N NZ . LYS A 1 513 ? 39.390 116.600 18.561 1.00 36.59 ? 513 LYS A NZ 1 ATOM 4106 N N . THR A 1 514 ? 37.732 117.681 26.560 1.00 28.34 ? 514 THR A N 1 ATOM 4107 C CA . THR A 1 514 ? 36.798 118.384 27.444 1.00 28.16 ? 514 THR A CA 1 ATOM 4108 C C . THR A 1 514 ? 37.346 118.403 28.846 1.00 28.27 ? 514 THR A C 1 ATOM 4109 O O . THR A 1 514 ? 37.310 119.429 29.498 1.00 28.31 ? 514 THR A O 1 ATOM 4110 C CB . THR A 1 514 ? 35.403 117.738 27.466 1.00 29.10 ? 514 THR A CB 1 ATOM 4111 O OG1 . THR A 1 514 ? 34.796 117.852 26.174 1.00 29.94 ? 514 THR A OG1 1 ATOM 4112 C CG2 . THR A 1 514 ? 34.482 118.411 28.537 1.00 28.07 ? 514 THR A CG2 1 ATOM 4113 N N . VAL A 1 515 ? 37.866 117.264 29.300 1.00 27.65 ? 515 VAL A N 1 ATOM 4114 C CA . VAL A 1 515 ? 38.317 117.098 30.671 1.00 27.68 ? 515 VAL A CA 1 ATOM 4115 C C . VAL A 1 515 ? 39.680 117.775 30.938 1.00 26.89 ? 515 VAL A C 1 ATOM 4116 O O . VAL A 1 515 ? 39.913 118.295 32.036 1.00 26.66 ? 515 VAL A O 1 ATOM 4117 C CB . VAL A 1 515 ? 38.392 115.588 31.017 1.00 27.94 ? 515 VAL A CB 1 ATOM 4118 C CG1 . VAL A 1 515 ? 38.976 115.352 32.414 1.00 28.54 ? 515 VAL A CG1 1 ATOM 4119 C CG2 . VAL A 1 515 ? 37.032 114.971 30.900 1.00 29.17 ? 515 VAL A CG2 1 ATOM 4120 N N . PHE A 1 516 ? 40.557 117.755 29.939 1.00 25.70 ? 516 PHE A N 1 ATOM 4121 C CA . PHE A 1 516 ? 41.896 118.364 30.053 1.00 26.13 ? 516 PHE A CA 1 ATOM 4122 C C . PHE A 1 516 ? 42.108 119.370 28.918 1.00 25.74 ? 516 PHE A C 1 ATOM 4123 O O . PHE A 1 516 ? 42.912 119.107 28.011 1.00 25.33 ? 516 PHE A O 1 ATOM 4124 C CB . PHE A 1 516 ? 43.006 117.266 30.002 1.00 26.09 ? 516 PHE A CB 1 ATOM 4125 C CG . PHE A 1 516 ? 42.815 116.157 31.011 1.00 25.43 ? 516 PHE A CG 1 ATOM 4126 C CD1 . PHE A 1 516 ? 43.080 116.374 32.370 1.00 25.28 ? 516 PHE A CD1 1 ATOM 4127 C CD2 . PHE A 1 516 ? 42.370 114.893 30.603 1.00 25.05 ? 516 PHE A CD2 1 ATOM 4128 C CE1 . PHE A 1 516 ? 42.891 115.343 33.306 1.00 27.00 ? 516 PHE A CE1 1 ATOM 4129 C CE2 . PHE A 1 516 ? 42.172 113.846 31.542 1.00 25.29 ? 516 PHE A CE2 1 ATOM 4130 C CZ . PHE A 1 516 ? 42.423 114.074 32.883 1.00 25.45 ? 516 PHE A CZ 1 ATOM 4131 N N . PRO A 1 517 ? 41.376 120.517 28.944 1.00 26.07 ? 517 PRO A N 1 ATOM 4132 C CA . PRO A 1 517 ? 41.363 121.348 27.733 1.00 26.42 ? 517 PRO A CA 1 ATOM 4133 C C . PRO A 1 517 ? 42.781 121.802 27.362 1.00 26.27 ? 517 PRO A C 1 ATOM 4134 O O . PRO A 1 517 ? 43.519 122.230 28.241 1.00 25.57 ? 517 PRO A O 1 ATOM 4135 C CB . PRO A 1 517 ? 40.477 122.563 28.133 1.00 27.13 ? 517 PRO A CB 1 ATOM 4136 C CG . PRO A 1 517 ? 39.693 122.094 29.352 1.00 27.46 ? 517 PRO A CG 1 ATOM 4137 C CD . PRO A 1 517 ? 40.558 121.088 30.039 1.00 26.08 ? 517 PRO A CD 1 ATOM 4138 N N . ASN A 1 518 ? 43.136 121.659 26.087 1.00 26.24 ? 518 ASN A N 1 ATOM 4139 C CA . ASN A 1 518 ? 44.483 121.969 25.534 1.00 26.99 ? 518 ASN A CA 1 ATOM 4140 C C . ASN A 1 518 ? 45.683 121.158 26.033 1.00 25.90 ? 518 ASN A C 1 ATOM 4141 O O . ASN A 1 518 ? 46.826 121.530 25.756 1.00 25.83 ? 518 ASN A O 1 ATOM 4142 C CB . ASN A 1 518 ? 44.815 123.458 25.672 1.00 27.71 ? 518 ASN A CB 1 ATOM 4143 C CG . ASN A 1 518 ? 43.778 124.341 24.994 1.00 33.12 ? 518 ASN A CG 1 ATOM 4144 O OD1 . ASN A 1 518 ? 43.307 124.045 23.867 1.00 37.07 ? 518 ASN A OD1 1 ATOM 4145 N ND2 . ASN A 1 518 ? 43.388 125.414 25.687 1.00 34.00 ? 518 ASN A ND2 1 ATOM 4146 N N . LYS A 1 519 ? 45.439 120.091 26.777 1.00 24.67 ? 519 LYS A N 1 ATOM 4147 C CA . LYS A 1 519 ? 46.542 119.272 27.280 1.00 23.85 ? 519 LYS A CA 1 ATOM 4148 C C . LYS A 1 519 ? 46.568 117.933 26.590 1.00 23.04 ? 519 LYS A C 1 ATOM 4149 O O . LYS A 1 519 ? 45.555 117.464 26.062 1.00 23.56 ? 519 LYS A O 1 ATOM 4150 C CB . LYS A 1 519 ? 46.457 119.092 28.799 1.00 24.25 ? 519 LYS A CB 1 ATOM 4151 C CG . LYS A 1 519 ? 46.211 120.376 29.591 1.00 24.79 ? 519 LYS A CG 1 ATOM 4152 C CD . LYS A 1 519 ? 47.446 121.284 29.612 1.00 28.01 ? 519 LYS A CD 1 ATOM 4153 C CE . LYS A 1 519 ? 47.262 122.493 30.549 1.00 29.28 ? 519 LYS A CE 1 ATOM 4154 N NZ . LYS A 1 519 ? 48.341 123.513 30.369 1.00 31.12 ? 519 LYS A NZ 1 ATOM 4155 N N . ARG A 1 520 ? 47.746 117.327 26.568 1.00 21.89 ? 520 ARG A N 1 ATOM 4156 C CA . ARG A 1 520 ? 47.944 115.985 26.041 1.00 20.68 ? 520 ARG A CA 1 ATOM 4157 C C . ARG A 1 520 ? 47.374 114.930 26.977 1.00 21.08 ? 520 ARG A C 1 ATOM 4158 O O . ARG A 1 520 ? 46.884 113.890 26.517 1.00 22.25 ? 520 ARG A O 1 ATOM 4159 C CB . ARG A 1 520 ? 49.454 115.729 25.900 1.00 19.93 ? 520 ARG A CB 1 ATOM 4160 C CG . ARG A 1 520 ? 50.120 116.681 24.945 1.00 18.24 ? 520 ARG A CG 1 ATOM 4161 C CD . ARG A 1 520 ? 51.642 116.678 25.190 1.00 19.24 ? 520 ARG A CD 1 ATOM 4162 N NE . ARG A 1 520 ? 52.227 117.873 24.612 1.00 17.44 ? 520 ARG A NE 1 ATOM 4163 C CZ . ARG A 1 520 ? 53.517 118.155 24.654 1.00 19.22 ? 520 ARG A CZ 1 ATOM 4164 N NH1 . ARG A 1 520 ? 54.375 117.293 25.205 1.00 15.30 ? 520 ARG A NH1 1 ATOM 4165 N NH2 . ARG A 1 520 ? 53.939 119.289 24.146 1.00 18.22 ? 520 ARG A NH2 1 ATOM 4166 N N . SER A 1 521 ? 47.465 115.174 28.291 1.00 21.09 ? 521 SER A N 1 ATOM 4167 C CA . SER A 1 521 ? 47.161 114.166 29.289 1.00 20.78 ? 521 SER A CA 1 ATOM 4168 C C . SER A 1 521 ? 48.003 112.911 28.988 1.00 21.07 ? 521 SER A C 1 ATOM 4169 O O . SER A 1 521 ? 49.120 113.015 28.509 1.00 20.67 ? 521 SER A O 1 ATOM 4170 C CB . SER A 1 521 ? 45.655 113.854 29.232 1.00 20.50 ? 521 SER A CB 1 ATOM 4171 O OG . SER A 1 521 ? 45.278 112.946 30.253 1.00 23.50 ? 521 SER A OG 1 ATOM 4172 N N . PHE A 1 522 ? 47.434 111.730 29.225 1.00 21.17 ? 522 PHE A N 1 ATOM 4173 C CA . PHE A 1 522 ? 48.103 110.458 29.007 1.00 20.58 ? 522 PHE A CA 1 ATOM 4174 C C . PHE A 1 522 ? 47.030 109.403 28.838 1.00 20.60 ? 522 PHE A C 1 ATOM 4175 O O . PHE A 1 522 ? 46.132 109.326 29.671 1.00 20.98 ? 522 PHE A O 1 ATOM 4176 C CB . PHE A 1 522 ? 48.980 110.139 30.203 1.00 20.17 ? 522 PHE A CB 1 ATOM 4177 C CG . PHE A 1 522 ? 49.617 108.762 30.171 1.00 20.99 ? 522 PHE A CG 1 ATOM 4178 C CD1 . PHE A 1 522 ? 50.699 108.496 29.351 1.00 20.59 ? 522 PHE A CD1 1 ATOM 4179 C CD2 . PHE A 1 522 ? 49.159 107.744 31.027 1.00 20.57 ? 522 PHE A CD2 1 ATOM 4180 C CE1 . PHE A 1 522 ? 51.339 107.208 29.367 1.00 21.85 ? 522 PHE A CE1 1 ATOM 4181 C CE2 . PHE A 1 522 ? 49.788 106.452 31.048 1.00 22.53 ? 522 PHE A CE2 1 ATOM 4182 C CZ . PHE A 1 522 ? 50.880 106.200 30.239 1.00 19.46 ? 522 PHE A CZ 1 ATOM 4183 N N . ILE A 1 523 ? 47.081 108.627 27.744 1.00 20.13 ? 523 ILE A N 1 ATOM 4184 C CA . ILE A 1 523 ? 46.187 107.478 27.583 1.00 19.24 ? 523 ILE A CA 1 ATOM 4185 C C . ILE A 1 523 ? 47.016 106.238 27.366 1.00 19.26 ? 523 ILE A C 1 ATOM 4186 O O . ILE A 1 523 ? 47.832 106.218 26.465 1.00 20.39 ? 523 ILE A O 1 ATOM 4187 C CB . ILE A 1 523 ? 45.224 107.664 26.424 1.00 19.68 ? 523 ILE A CB 1 ATOM 4188 C CG1 . ILE A 1 523 ? 44.298 108.870 26.695 1.00 19.88 ? 523 ILE A CG1 1 ATOM 4189 C CG2 . ILE A 1 523 ? 44.395 106.359 26.167 1.00 19.06 ? 523 ILE A CG2 1 ATOM 4190 C CD1 . ILE A 1 523 ? 43.740 109.423 25.417 1.00 21.12 ? 523 ILE A CD1 1 ATOM 4191 N N . LEU A 1 524 ? 46.818 105.223 28.210 1.00 18.18 ? 524 LEU A N 1 ATOM 4192 C CA . LEU A 1 524 ? 47.499 103.947 28.104 1.00 16.62 ? 524 LEU A CA 1 ATOM 4193 C C . LEU A 1 524 ? 46.484 102.892 27.691 1.00 17.44 ? 524 LEU A C 1 ATOM 4194 O O . LEU A 1 524 ? 45.484 102.651 28.406 1.00 16.99 ? 524 LEU A O 1 ATOM 4195 C CB . LEU A 1 524 ? 48.151 103.582 29.432 1.00 15.73 ? 524 LEU A CB 1 ATOM 4196 C CG . LEU A 1 524 ? 48.950 102.272 29.503 1.00 17.30 ? 524 LEU A CG 1 ATOM 4197 C CD1 . LEU A 1 524 ? 50.153 102.311 28.569 1.00 9.09 ? 524 LEU A CD1 1 ATOM 4198 C CD2 . LEU A 1 524 ? 49.380 101.939 30.929 1.00 14.18 ? 524 LEU A CD2 1 ATOM 4199 N N . THR A 1 525 ? 46.713 102.267 26.533 1.00 17.16 ? 525 THR A N 1 ATOM 4200 C CA . THR A 1 525 ? 45.754 101.264 26.015 1.00 17.05 ? 525 THR A CA 1 ATOM 4201 C C . THR A 1 525 ? 46.375 99.885 25.850 1.00 17.19 ? 525 THR A C 1 ATOM 4202 O O . THR A 1 525 ? 47.578 99.776 25.606 1.00 15.98 ? 525 THR A O 1 ATOM 4203 C CB . THR A 1 525 ? 45.093 101.707 24.691 1.00 17.08 ? 525 THR A CB 1 ATOM 4204 O OG1 . THR A 1 525 ? 44.023 100.807 24.382 1.00 18.40 ? 525 THR A OG1 1 ATOM 4205 C CG2 . THR A 1 525 ? 46.074 101.681 23.544 1.00 17.92 ? 525 THR A CG2 1 ATOM 4206 N N . ARG A 1 526 ? 45.550 98.851 26.031 1.00 16.79 ? 526 ARG A N 1 ATOM 4207 C CA . ARG A 1 526 ? 45.964 97.480 25.886 1.00 17.45 ? 526 ARG A CA 1 ATOM 4208 C C . ARG A 1 526 ? 45.832 97.035 24.435 1.00 18.34 ? 526 ARG A C 1 ATOM 4209 O O . ARG A 1 526 ? 46.838 96.756 23.749 1.00 18.77 ? 526 ARG A O 1 ATOM 4210 C CB . ARG A 1 526 ? 45.139 96.539 26.790 1.00 16.79 ? 526 ARG A CB 1 ATOM 4211 C CG . ARG A 1 526 ? 45.890 95.213 26.965 1.00 16.42 ? 526 ARG A CG 1 ATOM 4212 C CD . ARG A 1 526 ? 45.505 94.491 28.196 1.00 19.18 ? 526 ARG A CD 1 ATOM 4213 N NE . ARG A 1 526 ? 44.276 93.780 27.906 1.00 19.61 ? 526 ARG A NE 1 ATOM 4214 C CZ . ARG A 1 526 ? 43.705 92.964 28.767 1.00 22.04 ? 526 ARG A CZ 1 ATOM 4215 N NH1 . ARG A 1 526 ? 44.263 92.811 29.958 1.00 21.17 ? 526 ARG A NH1 1 ATOM 4216 N NH2 . ARG A 1 526 ? 42.606 92.301 28.425 1.00 19.68 ? 526 ARG A NH2 1 ATOM 4217 N N . SER A 1 527 ? 44.582 96.963 23.971 1.00 18.14 ? 527 SER A N 1 ATOM 4218 C CA . SER A 1 527 ? 44.327 96.626 22.603 1.00 18.79 ? 527 SER A CA 1 ATOM 4219 C C . SER A 1 527 ? 44.592 97.800 21.634 1.00 18.33 ? 527 SER A C 1 ATOM 4220 O O . SER A 1 527 ? 44.362 98.961 21.955 1.00 18.84 ? 527 SER A O 1 ATOM 4221 C CB . SER A 1 527 ? 42.915 96.091 22.463 1.00 19.27 ? 527 SER A CB 1 ATOM 4222 O OG . SER A 1 527 ? 42.629 95.960 21.106 1.00 21.34 ? 527 SER A OG 1 ATOM 4223 N N . THR A 1 528 ? 45.134 97.475 20.465 1.00 18.83 ? 528 THR A N 1 ATOM 4224 C CA . THR A 1 528 ? 45.534 98.454 19.432 1.00 18.21 ? 528 THR A CA 1 ATOM 4225 C C . THR A 1 528 ? 45.223 97.913 18.026 1.00 18.20 ? 528 THR A C 1 ATOM 4226 O O . THR A 1 528 ? 45.078 96.695 17.818 1.00 18.96 ? 528 THR A O 1 ATOM 4227 C CB . THR A 1 528 ? 47.047 98.835 19.486 1.00 18.64 ? 528 THR A CB 1 ATOM 4228 O OG1 . THR A 1 528 ? 47.856 97.674 19.277 1.00 19.85 ? 528 THR A OG1 1 ATOM 4229 C CG2 . THR A 1 528 ? 47.435 99.499 20.846 1.00 17.12 ? 528 THR A CG2 1 ATOM 4230 N N . PHE A 1 529 ? 45.072 98.841 17.085 1.00 17.43 ? 529 PHE A N 1 ATOM 4231 C CA . PHE A 1 529 ? 45.063 98.565 15.675 1.00 17.26 ? 529 PHE A CA 1 ATOM 4232 C C . PHE A 1 529 ? 46.159 99.463 15.099 1.00 17.23 ? 529 PHE A C 1 ATOM 4233 O O . PHE A 1 529 ? 46.764 100.241 15.832 1.00 18.02 ? 529 PHE A O 1 ATOM 4234 C CB . PHE A 1 529 ? 43.700 98.910 15.055 1.00 16.76 ? 529 PHE A CB 1 ATOM 4235 C CG . PHE A 1 529 ? 43.535 98.398 13.632 1.00 16.78 ? 529 PHE A CG 1 ATOM 4236 C CD1 . PHE A 1 529 ? 43.432 97.033 13.381 1.00 16.40 ? 529 PHE A CD1 1 ATOM 4237 C CD2 . PHE A 1 529 ? 43.523 99.295 12.552 1.00 16.50 ? 529 PHE A CD2 1 ATOM 4238 C CE1 . PHE A 1 529 ? 43.345 96.549 12.087 1.00 13.66 ? 529 PHE A CE1 1 ATOM 4239 C CE2 . PHE A 1 529 ? 43.416 98.846 11.260 1.00 16.03 ? 529 PHE A CE2 1 ATOM 4240 C CZ . PHE A 1 529 ? 43.324 97.467 11.011 1.00 16.88 ? 529 PHE A CZ 1 ATOM 4241 N N . ALA A 1 530 ? 46.400 99.388 13.797 1.00 16.89 ? 530 ALA A N 1 ATOM 4242 C CA . ALA A 1 530 ? 47.396 100.269 13.171 1.00 17.23 ? 530 ALA A CA 1 ATOM 4243 C C . ALA A 1 530 ? 46.972 101.706 13.257 1.00 16.76 ? 530 ALA A C 1 ATOM 4244 O O . ALA A 1 530 ? 45.861 102.054 12.891 1.00 16.52 ? 530 ALA A O 1 ATOM 4245 C CB . ALA A 1 530 ? 47.607 99.874 11.738 1.00 17.12 ? 530 ALA A CB 1 ATOM 4246 N N . GLY A 1 531 ? 47.866 102.572 13.711 1.00 16.59 ? 531 GLY A N 1 ATOM 4247 C CA . GLY A 1 531 ? 47.481 103.963 13.907 1.00 15.09 ? 531 GLY A CA 1 ATOM 4248 C C . GLY A 1 531 ? 47.111 104.376 15.327 1.00 15.91 ? 531 GLY A C 1 ATOM 4249 O O . GLY A 1 531 ? 46.928 105.560 15.570 1.00 16.08 ? 531 GLY A O 1 ATOM 4250 N N . SER A 1 532 ? 47.017 103.421 16.263 1.00 16.44 ? 532 SER A N 1 ATOM 4251 C CA . SER A 1 532 ? 46.690 103.685 17.671 1.00 16.99 ? 532 SER A CA 1 ATOM 4252 C C . SER A 1 532 ? 47.648 104.611 18.415 1.00 17.31 ? 532 SER A C 1 ATOM 4253 O O . SER A 1 532 ? 47.252 105.296 19.380 1.00 16.30 ? 532 SER A O 1 ATOM 4254 C CB . SER A 1 532 ? 46.577 102.387 18.468 1.00 17.19 ? 532 SER A CB 1 ATOM 4255 O OG . SER A 1 532 ? 45.326 101.751 18.283 1.00 21.23 ? 532 SER A OG 1 ATOM 4256 N N . GLY A 1 533 ? 48.910 104.637 17.990 1.00 16.91 ? 533 GLY A N 1 ATOM 4257 C CA . GLY A 1 533 ? 49.893 105.516 18.633 1.00 15.94 ? 533 GLY A CA 1 ATOM 4258 C C . GLY A 1 533 ? 49.606 106.995 18.450 1.00 16.73 ? 533 GLY A C 1 ATOM 4259 O O . GLY A 1 533 ? 50.187 107.851 19.156 1.00 14.70 ? 533 GLY A O 1 ATOM 4260 N N . LYS A 1 534 ? 48.750 107.334 17.483 1.00 16.28 ? 534 LYS A N 1 ATOM 4261 C CA . LYS A 1 534 ? 48.328 108.731 17.331 1.00 17.14 ? 534 LYS A CA 1 ATOM 4262 C C . LYS A 1 534 ? 47.605 109.208 18.585 1.00 18.76 ? 534 LYS A C 1 ATOM 4263 O O . LYS A 1 534 ? 47.502 110.411 18.829 1.00 19.84 ? 534 LYS A O 1 ATOM 4264 C CB . LYS A 1 534 ? 47.426 108.864 16.114 1.00 17.31 ? 534 LYS A CB 1 ATOM 4265 C CG . LYS A 1 534 ? 46.941 110.267 15.802 1.00 18.68 ? 534 LYS A CG 1 ATOM 4266 C CD . LYS A 1 534 ? 46.164 110.277 14.485 1.00 20.60 ? 534 LYS A CD 1 ATOM 4267 C CE . LYS A 1 534 ? 45.434 111.637 14.256 1.00 24.60 ? 534 LYS A CE 1 ATOM 4268 N NZ . LYS A 1 534 ? 44.645 111.658 12.983 1.00 25.19 ? 534 LYS A NZ 1 ATOM 4269 N N . PHE A 1 535 ? 47.116 108.256 19.395 1.00 19.02 ? 535 PHE A N 1 ATOM 4270 C CA . PHE A 1 535 ? 46.147 108.541 20.470 1.00 18.83 ? 535 PHE A CA 1 ATOM 4271 C C . PHE A 1 535 ? 46.615 108.054 21.815 1.00 19.24 ? 535 PHE A C 1 ATOM 4272 O O . PHE A 1 535 ? 46.180 108.615 22.800 1.00 20.20 ? 535 PHE A O 1 ATOM 4273 C CB . PHE A 1 535 ? 44.759 107.907 20.209 1.00 19.28 ? 535 PHE A CB 1 ATOM 4274 C CG . PHE A 1 535 ? 44.130 108.362 18.946 1.00 21.25 ? 535 PHE A CG 1 ATOM 4275 C CD1 . PHE A 1 535 ? 43.583 109.641 18.841 1.00 22.62 ? 535 PHE A CD1 1 ATOM 4276 C CD2 . PHE A 1 535 ? 44.129 107.540 17.831 1.00 24.32 ? 535 PHE A CD2 1 ATOM 4277 C CE1 . PHE A 1 535 ? 43.016 110.075 17.651 1.00 24.39 ? 535 PHE A CE1 1 ATOM 4278 C CE2 . PHE A 1 535 ? 43.577 107.982 16.613 1.00 23.46 ? 535 PHE A CE2 1 ATOM 4279 C CZ . PHE A 1 535 ? 43.017 109.237 16.530 1.00 22.29 ? 535 PHE A CZ 1 ATOM 4280 N N . ALA A 1 536 ? 47.498 107.034 21.863 1.00 17.35 ? 536 ALA A N 1 ATOM 4281 C CA . ALA A 1 536 ? 47.748 106.309 23.084 1.00 16.68 ? 536 ALA A CA 1 ATOM 4282 C C . ALA A 1 536 ? 49.119 105.666 23.198 1.00 16.62 ? 536 ALA A C 1 ATOM 4283 O O . ALA A 1 536 ? 49.759 105.336 22.199 1.00 17.08 ? 536 ALA A O 1 ATOM 4284 C CB . ALA A 1 536 ? 46.635 105.223 23.296 1.00 16.64 ? 536 ALA A CB 1 ATOM 4285 N N . ALA A 1 537 ? 49.553 105.477 24.432 1.00 15.97 ? 537 ALA A N 1 ATOM 4286 C CA . ALA A 1 537 ? 50.702 104.620 24.751 1.00 16.66 ? 537 ALA A CA 1 ATOM 4287 C C . ALA A 1 537 ? 50.185 103.195 24.888 1.00 16.54 ? 537 ALA A C 1 ATOM 4288 O O . ALA A 1 537 ? 48.964 102.985 24.993 1.00 16.40 ? 537 ALA A O 1 ATOM 4289 C CB . ALA A 1 537 ? 51.339 105.088 26.089 1.00 16.04 ? 537 ALA A CB 1 ATOM 4290 N N . HIS A 1 538 ? 51.093 102.233 24.939 1.00 15.42 ? 538 HIS A N 1 ATOM 4291 C CA . HIS A 1 538 ? 50.707 100.836 25.036 1.00 16.40 ? 538 HIS A CA 1 ATOM 4292 C C . HIS A 1 538 ? 51.620 100.173 26.067 1.00 16.59 ? 538 HIS A C 1 ATOM 4293 O O . HIS A 1 538 ? 52.754 100.613 26.266 1.00 16.01 ? 538 HIS A O 1 ATOM 4294 C CB . HIS A 1 538 ? 50.810 100.158 23.656 1.00 16.33 ? 538 HIS A CB 1 ATOM 4295 C CG . HIS A 1 538 ? 50.626 98.676 23.688 1.00 19.56 ? 538 HIS A CG 1 ATOM 4296 N ND1 . HIS A 1 538 ? 49.449 98.072 24.089 1.00 17.94 ? 538 HIS A ND1 1 ATOM 4297 C CD2 . HIS A 1 538 ? 51.482 97.668 23.376 1.00 21.50 ? 538 HIS A CD2 1 ATOM 4298 C CE1 . HIS A 1 538 ? 49.579 96.762 23.993 1.00 21.14 ? 538 HIS A CE1 1 ATOM 4299 N NE2 . HIS A 1 538 ? 50.806 96.490 23.585 1.00 22.79 ? 538 HIS A NE2 1 ATOM 4300 N N . TRP A 1 539 ? 51.112 99.148 26.763 1.00 16.50 ? 539 TRP A N 1 ATOM 4301 C CA . TRP A 1 539 ? 51.985 98.270 27.517 1.00 15.86 ? 539 TRP A CA 1 ATOM 4302 C C . TRP A 1 539 ? 51.800 96.833 27.050 1.00 16.99 ? 539 TRP A C 1 ATOM 4303 O O . TRP A 1 539 ? 50.709 96.459 26.552 1.00 17.51 ? 539 TRP A O 1 ATOM 4304 C CB . TRP A 1 539 ? 51.813 98.429 29.046 1.00 15.81 ? 539 TRP A CB 1 ATOM 4305 C CG . TRP A 1 539 ? 50.788 97.563 29.701 1.00 15.26 ? 539 TRP A CG 1 ATOM 4306 C CD1 . TRP A 1 539 ? 51.024 96.481 30.510 1.00 16.52 ? 539 TRP A CD1 1 ATOM 4307 C CD2 . TRP A 1 539 ? 49.349 97.703 29.634 1.00 17.02 ? 539 TRP A CD2 1 ATOM 4308 N NE1 . TRP A 1 539 ? 49.820 95.947 30.956 1.00 16.10 ? 539 TRP A NE1 1 ATOM 4309 C CE2 . TRP A 1 539 ? 48.787 96.673 30.428 1.00 15.75 ? 539 TRP A CE2 1 ATOM 4310 C CE3 . TRP A 1 539 ? 48.487 98.611 28.992 1.00 17.07 ? 539 TRP A CE3 1 ATOM 4311 C CZ2 . TRP A 1 539 ? 47.405 96.519 30.591 1.00 17.97 ? 539 TRP A CZ2 1 ATOM 4312 C CZ3 . TRP A 1 539 ? 47.106 98.451 29.146 1.00 15.71 ? 539 TRP A CZ3 1 ATOM 4313 C CH2 . TRP A 1 539 ? 46.582 97.399 29.936 1.00 13.65 ? 539 TRP A CH2 1 ATOM 4314 N N . LEU A 1 540 ? 52.821 96.004 27.269 1.00 15.61 ? 540 LEU A N 1 ATOM 4315 C CA . LEU A 1 540 ? 52.851 94.681 26.657 1.00 17.30 ? 540 LEU A CA 1 ATOM 4316 C C . LEU A 1 540 ? 51.964 93.633 27.378 1.00 18.83 ? 540 LEU A C 1 ATOM 4317 O O . LEU A 1 540 ? 51.944 92.469 26.982 1.00 20.43 ? 540 LEU A O 1 ATOM 4318 C CB . LEU A 1 540 ? 54.303 94.189 26.435 1.00 15.37 ? 540 LEU A CB 1 ATOM 4319 C CG . LEU A 1 540 ? 55.215 95.148 25.644 1.00 16.24 ? 540 LEU A CG 1 ATOM 4320 C CD1 . LEU A 1 540 ? 56.638 94.618 25.571 1.00 16.20 ? 540 LEU A CD1 1 ATOM 4321 C CD2 . LEU A 1 540 ? 54.638 95.302 24.260 1.00 15.73 ? 540 LEU A CD2 1 ATOM 4322 N N . GLY A 1 541 ? 51.216 94.059 28.393 1.00 19.29 ? 541 GLY A N 1 ATOM 4323 C CA . GLY A 1 541 ? 50.166 93.254 29.010 1.00 19.51 ? 541 GLY A CA 1 ATOM 4324 C C . GLY A 1 541 ? 50.598 92.429 30.229 1.00 19.62 ? 541 GLY A C 1 ATOM 4325 O O . GLY A 1 541 ? 51.603 92.729 30.889 1.00 18.34 ? 541 GLY A O 1 ATOM 4326 N N . ASP A 1 542 ? 49.836 91.365 30.497 1.00 18.65 ? 542 ASP A N 1 ATOM 4327 C CA . ASP A 1 542 ? 50.012 90.539 31.700 1.00 18.78 ? 542 ASP A CA 1 ATOM 4328 C C . ASP A 1 542 ? 51.145 89.522 31.547 1.00 17.91 ? 542 ASP A C 1 ATOM 4329 O O . ASP A 1 542 ? 50.902 88.338 31.297 1.00 17.53 ? 542 ASP A O 1 ATOM 4330 C CB . ASP A 1 542 ? 48.712 89.796 32.028 1.00 17.69 ? 542 ASP A CB 1 ATOM 4331 C CG . ASP A 1 542 ? 47.511 90.733 32.154 1.00 21.95 ? 542 ASP A CG 1 ATOM 4332 O OD1 . ASP A 1 542 ? 47.738 91.956 32.366 1.00 22.30 ? 542 ASP A OD1 1 ATOM 4333 O OD2 . ASP A 1 542 ? 46.338 90.244 32.019 1.00 23.02 ? 542 ASP A OD2 1 ATOM 4334 N N . ASN A 1 543 ? 52.379 89.978 31.709 1.00 17.70 ? 543 ASN A N 1 ATOM 4335 C CA . ASN A 1 543 ? 53.516 89.091 31.694 1.00 17.49 ? 543 ASN A CA 1 ATOM 4336 C C . ASN A 1 543 ? 53.690 88.389 33.062 1.00 18.64 ? 543 ASN A C 1 ATOM 4337 O O . ASN A 1 543 ? 52.798 88.430 33.917 1.00 17.98 ? 543 ASN A O 1 ATOM 4338 C CB . ASN A 1 543 ? 54.794 89.876 31.256 1.00 17.56 ? 543 ASN A CB 1 ATOM 4339 C CG . ASN A 1 543 ? 55.154 90.978 32.232 1.00 17.65 ? 543 ASN A CG 1 ATOM 4340 O OD1 . ASN A 1 543 ? 54.421 91.217 33.191 1.00 19.21 ? 543 ASN A OD1 1 ATOM 4341 N ND2 . ASN A 1 543 ? 56.287 91.647 32.013 1.00 16.42 ? 543 ASN A ND2 1 ATOM 4342 N N . THR A 1 544 ? 54.861 87.780 33.273 1.00 18.74 ? 544 THR A N 1 ATOM 4343 C CA . THR A 1 544 ? 55.107 86.907 34.404 1.00 19.84 ? 544 THR A CA 1 ATOM 4344 C C . THR A 1 544 ? 56.497 87.193 34.921 1.00 19.39 ? 544 THR A C 1 ATOM 4345 O O . THR A 1 544 ? 57.344 87.558 34.147 1.00 19.67 ? 544 THR A O 1 ATOM 4346 C CB . THR A 1 544 ? 55.034 85.435 33.947 1.00 20.05 ? 544 THR A CB 1 ATOM 4347 O OG1 . THR A 1 544 ? 53.779 85.253 33.270 1.00 24.11 ? 544 THR A OG1 1 ATOM 4348 C CG2 . THR A 1 544 ? 55.085 84.500 35.128 1.00 17.92 ? 544 THR A CG2 1 ATOM 4349 N N . ALA A 1 545 ? 56.735 87.050 36.224 1.00 19.92 ? 545 ALA A N 1 ATOM 4350 C CA . ALA A 1 545 ? 58.064 87.319 36.757 1.00 19.89 ? 545 ALA A CA 1 ATOM 4351 C C . ALA A 1 545 ? 58.994 86.154 36.449 1.00 20.14 ? 545 ALA A C 1 ATOM 4352 O O . ALA A 1 545 ? 59.389 85.433 37.373 1.00 20.06 ? 545 ALA A O 1 ATOM 4353 C CB . ALA A 1 545 ? 58.007 87.582 38.270 1.00 19.71 ? 545 ALA A CB 1 ATOM 4354 N N . THR A 1 546 ? 59.356 85.989 35.170 1.00 19.59 ? 546 THR A N 1 ATOM 4355 C CA . THR A 1 546 ? 60.393 85.005 34.755 1.00 19.82 ? 546 THR A CA 1 ATOM 4356 C C . THR A 1 546 ? 61.516 85.691 33.957 1.00 20.35 ? 546 THR A C 1 ATOM 4357 O O . THR A 1 546 ? 61.316 86.762 33.389 1.00 20.31 ? 546 THR A O 1 ATOM 4358 C CB . THR A 1 546 ? 59.821 83.842 33.878 1.00 20.41 ? 546 THR A CB 1 ATOM 4359 O OG1 . THR A 1 546 ? 59.351 84.362 32.642 1.00 20.93 ? 546 THR A OG1 1 ATOM 4360 C CG2 . THR A 1 546 ? 58.651 83.072 34.536 1.00 19.58 ? 546 THR A CG2 1 ATOM 4361 N N . TRP A 1 547 ? 62.699 85.076 33.910 1.00 21.01 ? 547 TRP A N 1 ATOM 4362 C CA . TRP A 1 547 ? 63.794 85.524 33.030 1.00 20.82 ? 547 TRP A CA 1 ATOM 4363 C C . TRP A 1 547 ? 63.461 85.510 31.517 1.00 21.58 ? 547 TRP A C 1 ATOM 4364 O O . TRP A 1 547 ? 63.950 86.384 30.751 1.00 21.30 ? 547 TRP A O 1 ATOM 4365 C CB . TRP A 1 547 ? 65.061 84.731 33.356 1.00 21.87 ? 547 TRP A CB 1 ATOM 4366 C CG . TRP A 1 547 ? 65.542 85.076 34.733 1.00 20.07 ? 547 TRP A CG 1 ATOM 4367 C CD1 . TRP A 1 547 ? 65.174 84.481 35.923 1.00 21.92 ? 547 TRP A CD1 1 ATOM 4368 C CD2 . TRP A 1 547 ? 66.435 86.132 35.072 1.00 21.90 ? 547 TRP A CD2 1 ATOM 4369 N NE1 . TRP A 1 547 ? 65.820 85.097 36.981 1.00 20.93 ? 547 TRP A NE1 1 ATOM 4370 C CE2 . TRP A 1 547 ? 66.600 86.112 36.480 1.00 20.98 ? 547 TRP A CE2 1 ATOM 4371 C CE3 . TRP A 1 547 ? 67.130 87.087 34.322 1.00 19.28 ? 547 TRP A CE3 1 ATOM 4372 C CZ2 . TRP A 1 547 ? 67.418 87.017 37.141 1.00 21.11 ? 547 TRP A CZ2 1 ATOM 4373 C CZ3 . TRP A 1 547 ? 67.960 87.973 34.982 1.00 22.22 ? 547 TRP A CZ3 1 ATOM 4374 C CH2 . TRP A 1 547 ? 68.085 87.947 36.376 1.00 21.91 ? 547 TRP A CH2 1 ATOM 4375 N N . ASP A 1 548 ? 62.606 84.553 31.105 1.00 20.81 ? 548 ASP A N 1 ATOM 4376 C CA . ASP A 1 548 ? 62.064 84.497 29.748 1.00 20.89 ? 548 ASP A CA 1 ATOM 4377 C C . ASP A 1 548 ? 61.254 85.755 29.445 1.00 19.88 ? 548 ASP A C 1 ATOM 4378 O O . ASP A 1 548 ? 61.458 86.363 28.398 1.00 20.03 ? 548 ASP A O 1 ATOM 4379 C CB . ASP A 1 548 ? 61.158 83.267 29.534 1.00 21.07 ? 548 ASP A CB 1 ATOM 4380 C CG . ASP A 1 548 ? 61.932 82.007 29.143 1.00 23.96 ? 548 ASP A CG 1 ATOM 4381 O OD1 . ASP A 1 548 ? 63.086 82.062 28.665 1.00 24.83 ? 548 ASP A OD1 1 ATOM 4382 O OD2 . ASP A 1 548 ? 61.352 80.934 29.306 1.00 25.53 ? 548 ASP A OD2 1 ATOM 4383 N N . ASP A 1 549 ? 60.314 86.130 30.321 1.00 20.04 ? 549 ASP A N 1 ATOM 4384 C CA . ASP A 1 549 ? 59.569 87.388 30.106 1.00 19.63 ? 549 ASP A CA 1 ATOM 4385 C C . ASP A 1 549 ? 60.451 88.635 30.028 1.00 19.92 ? 549 ASP A C 1 ATOM 4386 O O . ASP A 1 549 ? 60.160 89.516 29.215 1.00 20.52 ? 549 ASP A O 1 ATOM 4387 C CB . ASP A 1 549 ? 58.431 87.603 31.098 1.00 19.53 ? 549 ASP A CB 1 ATOM 4388 C CG . ASP A 1 549 ? 57.327 86.562 30.959 1.00 20.98 ? 549 ASP A CG 1 ATOM 4389 O OD1 . ASP A 1 549 ? 56.204 86.864 30.531 1.00 20.02 ? 549 ASP A OD1 1 ATOM 4390 O OD2 . ASP A 1 549 ? 57.594 85.414 31.299 1.00 23.56 ? 549 ASP A OD2 1 ATOM 4391 N N . LEU A 1 550 ? 61.494 88.719 30.856 1.00 19.17 ? 550 LEU A N 1 ATOM 4392 C CA . LEU A 1 550 ? 62.488 89.812 30.730 1.00 18.89 ? 550 LEU A CA 1 ATOM 4393 C C . LEU A 1 550 ? 63.098 89.863 29.320 1.00 19.19 ? 550 LEU A C 1 ATOM 4394 O O . LEU A 1 550 ? 63.058 90.918 28.663 1.00 19.59 ? 550 LEU A O 1 ATOM 4395 C CB . LEU A 1 550 ? 63.564 89.707 31.831 1.00 18.15 ? 550 LEU A CB 1 ATOM 4396 C CG . LEU A 1 550 ? 64.783 90.644 31.788 1.00 19.97 ? 550 LEU A CG 1 ATOM 4397 C CD1 . LEU A 1 550 ? 64.318 92.070 31.935 1.00 24.59 ? 550 LEU A CD1 1 ATOM 4398 C CD2 . LEU A 1 550 ? 65.773 90.312 32.874 1.00 18.85 ? 550 LEU A CD2 1 ATOM 4399 N N . ARG A 1 551 ? 63.629 88.734 28.830 1.00 19.67 ? 551 ARG A N 1 ATOM 4400 C CA . ARG A 1 551 ? 64.238 88.695 27.487 1.00 20.18 ? 551 ARG A CA 1 ATOM 4401 C C . ARG A 1 551 ? 63.260 89.104 26.390 1.00 20.35 ? 551 ARG A C 1 ATOM 4402 O O . ARG A 1 551 ? 63.604 89.912 25.501 1.00 21.56 ? 551 ARG A O 1 ATOM 4403 C CB . ARG A 1 551 ? 64.874 87.325 27.186 1.00 19.66 ? 551 ARG A CB 1 ATOM 4404 C CG . ARG A 1 551 ? 66.098 87.097 28.048 1.00 19.75 ? 551 ARG A CG 1 ATOM 4405 C CD . ARG A 1 551 ? 66.815 85.745 27.770 1.00 22.29 ? 551 ARG A CD 1 ATOM 4406 N NE . ARG A 1 551 ? 66.038 84.595 28.248 1.00 25.50 ? 551 ARG A NE 1 ATOM 4407 C CZ . ARG A 1 551 ? 66.179 84.017 29.448 1.00 26.00 ? 551 ARG A CZ 1 ATOM 4408 N NH1 . ARG A 1 551 ? 67.054 84.483 30.339 1.00 26.51 ? 551 ARG A NH1 1 ATOM 4409 N NH2 . ARG A 1 551 ? 65.434 82.964 29.767 1.00 21.62 ? 551 ARG A NH2 1 ATOM 4410 N N . TRP A 1 552 ? 62.044 88.571 26.473 1.00 18.79 ? 552 TRP A N 1 ATOM 4411 C CA . TRP A 1 552 ? 61.051 88.733 25.431 1.00 19.71 ? 552 TRP A CA 1 ATOM 4412 C C . TRP A 1 552 ? 60.557 90.134 25.305 1.00 19.34 ? 552 TRP A C 1 ATOM 4413 O O . TRP A 1 552 ? 59.984 90.472 24.271 1.00 19.63 ? 552 TRP A O 1 ATOM 4414 C CB . TRP A 1 552 ? 59.832 87.829 25.683 1.00 19.39 ? 552 TRP A CB 1 ATOM 4415 C CG . TRP A 1 552 ? 60.156 86.380 25.595 1.00 21.14 ? 552 TRP A CG 1 ATOM 4416 C CD1 . TRP A 1 552 ? 61.224 85.807 24.935 1.00 21.08 ? 552 TRP A CD1 1 ATOM 4417 C CD2 . TRP A 1 552 ? 59.419 85.298 26.186 1.00 20.43 ? 552 TRP A CD2 1 ATOM 4418 N NE1 . TRP A 1 552 ? 61.187 84.450 25.111 1.00 21.79 ? 552 TRP A NE1 1 ATOM 4419 C CE2 . TRP A 1 552 ? 60.075 84.112 25.837 1.00 18.44 ? 552 TRP A CE2 1 ATOM 4420 C CE3 . TRP A 1 552 ? 58.256 85.228 26.972 1.00 22.20 ? 552 TRP A CE3 1 ATOM 4421 C CZ2 . TRP A 1 552 ? 59.617 82.854 26.239 1.00 21.57 ? 552 TRP A CZ2 1 ATOM 4422 C CZ3 . TRP A 1 552 ? 57.803 83.974 27.385 1.00 21.42 ? 552 TRP A CZ3 1 ATOM 4423 C CH2 . TRP A 1 552 ? 58.491 82.806 27.014 1.00 21.04 ? 552 TRP A CH2 1 ATOM 4424 N N . SER A 1 553 ? 60.773 90.941 26.347 1.00 19.13 ? 553 SER A N 1 ATOM 4425 C CA . SER A 1 553 ? 60.292 92.319 26.363 1.00 19.18 ? 553 SER A CA 1 ATOM 4426 C C . SER A 1 553 ? 60.928 93.174 25.259 1.00 18.59 ? 553 SER A C 1 ATOM 4427 O O . SER A 1 553 ? 60.276 94.072 24.719 1.00 17.80 ? 553 SER A O 1 ATOM 4428 C CB . SER A 1 553 ? 60.518 92.969 27.738 1.00 19.95 ? 553 SER A CB 1 ATOM 4429 O OG . SER A 1 553 ? 61.885 93.201 27.998 1.00 16.97 ? 553 SER A OG 1 ATOM 4430 N N . ILE A 1 554 ? 62.200 92.920 24.953 1.00 18.10 ? 554 ILE A N 1 ATOM 4431 C CA . ILE A 1 554 ? 62.930 93.810 24.042 1.00 17.83 ? 554 ILE A CA 1 ATOM 4432 C C . ILE A 1 554 ? 62.369 93.768 22.604 1.00 18.03 ? 554 ILE A C 1 ATOM 4433 O O . ILE A 1 554 ? 62.004 94.816 22.065 1.00 18.66 ? 554 ILE A O 1 ATOM 4434 C CB . ILE A 1 554 ? 64.512 93.689 24.136 1.00 18.93 ? 554 ILE A CB 1 ATOM 4435 C CG1 . ILE A 1 554 ? 65.010 94.023 25.567 1.00 18.79 ? 554 ILE A CG1 1 ATOM 4436 C CG2 . ILE A 1 554 ? 65.155 94.646 23.108 1.00 15.81 ? 554 ILE A CG2 1 ATOM 4437 C CD1 . ILE A 1 554 ? 66.504 93.703 25.867 1.00 19.30 ? 554 ILE A CD1 1 ATOM 4438 N N . PRO A 1 555 ? 62.278 92.565 21.977 1.00 18.09 ? 555 PRO A N 1 ATOM 4439 C CA . PRO A 1 555 ? 61.607 92.532 20.670 1.00 17.93 ? 555 PRO A CA 1 ATOM 4440 C C . PRO A 1 555 ? 60.207 93.190 20.689 1.00 17.63 ? 555 PRO A C 1 ATOM 4441 O O . PRO A 1 555 ? 59.879 93.917 19.760 1.00 16.45 ? 555 PRO A O 1 ATOM 4442 C CB . PRO A 1 555 ? 61.499 91.034 20.367 1.00 18.24 ? 555 PRO A CB 1 ATOM 4443 C CG . PRO A 1 555 ? 62.655 90.421 21.090 1.00 17.63 ? 555 PRO A CG 1 ATOM 4444 C CD . PRO A 1 555 ? 62.811 91.232 22.353 1.00 17.73 ? 555 PRO A CD 1 ATOM 4445 N N . GLY A 1 556 ? 59.415 92.961 21.738 1.00 18.21 ? 556 GLY A N 1 ATOM 4446 C CA . GLY A 1 556 ? 58.044 93.569 21.856 1.00 16.81 ? 556 GLY A CA 1 ATOM 4447 C C . GLY A 1 556 ? 58.090 95.104 21.878 1.00 17.37 ? 556 GLY A C 1 ATOM 4448 O O . GLY A 1 556 ? 57.293 95.764 21.234 1.00 18.45 ? 556 GLY A O 1 ATOM 4449 N N . VAL A 1 557 ? 59.030 95.681 22.632 1.00 16.03 ? 557 VAL A N 1 ATOM 4450 C CA . VAL A 1 557 ? 59.264 97.132 22.603 1.00 14.10 ? 557 VAL A CA 1 ATOM 4451 C C . VAL A 1 557 ? 59.717 97.664 21.214 1.00 13.95 ? 557 VAL A C 1 ATOM 4452 O O . VAL A 1 557 ? 59.228 98.692 20.739 1.00 13.75 ? 557 VAL A O 1 ATOM 4453 C CB . VAL A 1 557 ? 60.275 97.534 23.709 1.00 14.14 ? 557 VAL A CB 1 ATOM 4454 C CG1 . VAL A 1 557 ? 60.756 98.987 23.523 1.00 14.87 ? 557 VAL A CG1 1 ATOM 4455 C CG2 . VAL A 1 557 ? 59.689 97.357 25.078 1.00 12.72 ? 557 VAL A CG2 1 ATOM 4456 N N . LEU A 1 558 ? 60.636 96.949 20.554 1.00 13.42 ? 558 LEU A N 1 ATOM 4457 C CA . LEU A 1 558 ? 61.143 97.373 19.257 1.00 13.89 ? 558 LEU A CA 1 ATOM 4458 C C . LEU A 1 558 ? 60.099 97.333 18.194 1.00 14.89 ? 558 LEU A C 1 ATOM 4459 O O . LEU A 1 558 ? 60.016 98.247 17.402 1.00 15.25 ? 558 LEU A O 1 ATOM 4460 C CB . LEU A 1 558 ? 62.330 96.499 18.808 1.00 13.31 ? 558 LEU A CB 1 ATOM 4461 C CG . LEU A 1 558 ? 63.593 96.624 19.657 1.00 12.19 ? 558 LEU A CG 1 ATOM 4462 C CD1 . LEU A 1 558 ? 64.639 95.668 19.117 1.00 12.08 ? 558 LEU A CD1 1 ATOM 4463 C CD2 . LEU A 1 558 ? 64.076 98.056 19.725 1.00 13.62 ? 558 LEU A CD2 1 ATOM 4464 N N . GLU A 1 559 ? 59.291 96.272 18.190 1.00 15.13 ? 559 GLU A N 1 ATOM 4465 C CA . GLU A 1 559 ? 58.182 96.147 17.258 1.00 16.74 ? 559 GLU A CA 1 ATOM 4466 C C . GLU A 1 559 ? 57.142 97.259 17.396 1.00 16.49 ? 559 GLU A C 1 ATOM 4467 O O . GLU A 1 559 ? 56.646 97.779 16.380 1.00 17.91 ? 559 GLU A O 1 ATOM 4468 C CB . GLU A 1 559 ? 57.552 94.746 17.389 1.00 17.98 ? 559 GLU A CB 1 ATOM 4469 C CG . GLU A 1 559 ? 58.509 93.599 16.960 1.00 18.44 ? 559 GLU A CG 1 ATOM 4470 C CD . GLU A 1 559 ? 58.199 92.224 17.584 1.00 19.59 ? 559 GLU A CD 1 ATOM 4471 O OE1 . GLU A 1 559 ? 57.294 92.123 18.473 1.00 20.04 ? 559 GLU A OE1 1 ATOM 4472 O OE2 . GLU A 1 559 ? 58.869 91.239 17.157 1.00 19.29 ? 559 GLU A OE2 1 ATOM 4473 N N . PHE A 1 560 ? 56.782 97.654 18.624 1.00 15.88 ? 560 PHE A N 1 ATOM 4474 C CA . PHE A 1 560 ? 55.770 98.701 18.756 1.00 14.08 ? 560 PHE A CA 1 ATOM 4475 C C . PHE A 1 560 ? 56.293 100.055 18.330 1.00 14.47 ? 560 PHE A C 1 ATOM 4476 O O . PHE A 1 560 ? 55.521 100.936 17.923 1.00 12.50 ? 560 PHE A O 1 ATOM 4477 C CB . PHE A 1 560 ? 55.129 98.699 20.145 1.00 14.46 ? 560 PHE A CB 1 ATOM 4478 C CG . PHE A 1 560 ? 53.939 97.776 20.203 1.00 14.22 ? 560 PHE A CG 1 ATOM 4479 C CD1 . PHE A 1 560 ? 54.095 96.443 20.527 1.00 15.54 ? 560 PHE A CD1 1 ATOM 4480 C CD2 . PHE A 1 560 ? 52.689 98.235 19.781 1.00 17.49 ? 560 PHE A CD2 1 ATOM 4481 C CE1 . PHE A 1 560 ? 52.986 95.578 20.494 1.00 14.83 ? 560 PHE A CE1 1 ATOM 4482 C CE2 . PHE A 1 560 ? 51.583 97.400 19.744 1.00 14.73 ? 560 PHE A CE2 1 ATOM 4483 C CZ . PHE A 1 560 ? 51.729 96.090 20.102 1.00 14.84 ? 560 PHE A CZ 1 ATOM 4484 N N . ASN A 1 561 ? 57.615 100.220 18.394 1.00 13.29 ? 561 ASN A N 1 ATOM 4485 C CA . ASN A 1 561 ? 58.248 101.421 17.793 1.00 14.68 ? 561 ASN A CA 1 ATOM 4486 C C . ASN A 1 561 ? 58.171 101.434 16.261 1.00 15.06 ? 561 ASN A C 1 ATOM 4487 O O . ASN A 1 561 ? 57.920 102.470 15.657 1.00 17.69 ? 561 ASN A O 1 ATOM 4488 C CB . ASN A 1 561 ? 59.706 101.550 18.289 1.00 14.19 ? 561 ASN A CB 1 ATOM 4489 C CG . ASN A 1 561 ? 59.801 102.294 19.601 1.00 15.12 ? 561 ASN A CG 1 ATOM 4490 O OD1 . ASN A 1 561 ? 60.177 103.456 19.603 1.00 13.72 ? 561 ASN A OD1 1 ATOM 4491 N ND2 . ASN A 1 561 ? 59.480 101.634 20.724 1.00 14.00 ? 561 ASN A ND2 1 ATOM 4492 N N . LEU A 1 562 ? 58.332 100.290 15.601 1.00 16.19 ? 562 LEU A N 1 ATOM 4493 C CA . LEU A 1 562 ? 58.000 100.219 14.169 1.00 16.13 ? 562 LEU A CA 1 ATOM 4494 C C . LEU A 1 562 ? 56.535 100.561 13.899 1.00 16.70 ? 562 LEU A C 1 ATOM 4495 O O . LEU A 1 562 ? 56.203 101.141 12.863 1.00 17.19 ? 562 LEU A O 1 ATOM 4496 C CB . LEU A 1 562 ? 58.216 98.804 13.594 1.00 15.92 ? 562 LEU A CB 1 ATOM 4497 C CG . LEU A 1 562 ? 59.508 98.027 13.723 1.00 18.81 ? 562 LEU A CG 1 ATOM 4498 C CD1 . LEU A 1 562 ? 59.367 96.697 12.933 1.00 18.56 ? 562 LEU A CD1 1 ATOM 4499 C CD2 . LEU A 1 562 ? 60.692 98.896 13.205 1.00 16.90 ? 562 LEU A CD2 1 ATOM 4500 N N . PHE A 1 563 ? 55.659 100.134 14.800 1.00 16.40 ? 563 PHE A N 1 ATOM 4501 C CA . PHE A 1 563 ? 54.206 100.360 14.650 1.00 16.40 ? 563 PHE A CA 1 ATOM 4502 C C . PHE A 1 563 ? 53.789 101.804 14.976 1.00 16.91 ? 563 PHE A C 1 ATOM 4503 O O . PHE A 1 563 ? 52.623 102.173 14.824 1.00 17.62 ? 563 PHE A O 1 ATOM 4504 C CB . PHE A 1 563 ? 53.410 99.346 15.502 1.00 15.96 ? 563 PHE A CB 1 ATOM 4505 C CG . PHE A 1 563 ? 53.746 97.900 15.224 1.00 14.66 ? 563 PHE A CG 1 ATOM 4506 C CD1 . PHE A 1 563 ? 54.123 97.474 13.945 1.00 14.58 ? 563 PHE A CD1 1 ATOM 4507 C CD2 . PHE A 1 563 ? 53.633 96.947 16.250 1.00 13.64 ? 563 PHE A CD2 1 ATOM 4508 C CE1 . PHE A 1 563 ? 54.457 96.115 13.703 1.00 12.05 ? 563 PHE A CE1 1 ATOM 4509 C CE2 . PHE A 1 563 ? 53.929 95.627 16.031 1.00 15.03 ? 563 PHE A CE2 1 ATOM 4510 C CZ . PHE A 1 563 ? 54.349 95.204 14.739 1.00 14.86 ? 563 PHE A CZ 1 ATOM 4511 N N . GLY A 1 564 ? 54.755 102.641 15.383 1.00 17.12 ? 564 GLY A N 1 ATOM 4512 C CA . GLY A 1 564 ? 54.474 104.035 15.762 1.00 16.21 ? 564 GLY A CA 1 ATOM 4513 C C . GLY A 1 564 ? 53.747 104.212 17.098 1.00 16.53 ? 564 GLY A C 1 ATOM 4514 O O . GLY A 1 564 ? 52.965 105.162 17.297 1.00 16.35 ? 564 GLY A O 1 ATOM 4515 N N . ILE A 1 565 ? 53.969 103.273 17.994 1.00 15.82 ? 565 ILE A N 1 ATOM 4516 C CA . ILE A 1 565 ? 53.592 103.400 19.384 1.00 17.06 ? 565 ILE A CA 1 ATOM 4517 C C . ILE A 1 565 ? 54.898 103.371 20.215 1.00 17.19 ? 565 ILE A C 1 ATOM 4518 O O . ILE A 1 565 ? 55.180 102.376 20.882 1.00 17.07 ? 565 ILE A O 1 ATOM 4519 C CB . ILE A 1 565 ? 52.627 102.261 19.805 1.00 17.76 ? 565 ILE A CB 1 ATOM 4520 C CG1 . ILE A 1 565 ? 51.452 102.217 18.797 1.00 16.70 ? 565 ILE A CG1 1 ATOM 4521 C CG2 . ILE A 1 565 ? 52.152 102.555 21.217 1.00 19.21 ? 565 ILE A CG2 1 ATOM 4522 C CD1 . ILE A 1 565 ? 50.508 101.013 18.848 1.00 16.67 ? 565 ILE A CD1 1 ATOM 4523 N N . PRO A 1 566 ? 55.724 104.448 20.120 1.00 17.16 ? 566 PRO A N 1 ATOM 4524 C CA . PRO A 1 566 ? 57.031 104.443 20.765 1.00 17.37 ? 566 PRO A CA 1 ATOM 4525 C C . PRO A 1 566 ? 57.002 104.395 22.292 1.00 17.43 ? 566 PRO A C 1 ATOM 4526 O O . PRO A 1 566 ? 57.943 103.865 22.905 1.00 17.00 ? 566 PRO A O 1 ATOM 4527 C CB . PRO A 1 566 ? 57.691 105.736 20.259 1.00 17.02 ? 566 PRO A CB 1 ATOM 4528 C CG . PRO A 1 566 ? 56.596 106.617 19.874 1.00 17.93 ? 566 PRO A CG 1 ATOM 4529 C CD . PRO A 1 566 ? 55.485 105.712 19.393 1.00 17.26 ? 566 PRO A CD 1 ATOM 4530 N N . MET A 1 567 ? 55.960 104.973 22.895 1.00 17.79 ? 567 MET A N 1 ATOM 4531 C CA A MET A 1 567 ? 55.786 104.876 24.341 0.50 18.00 ? 567 MET A CA 1 ATOM 4532 C CA B MET A 1 567 ? 55.717 104.920 24.327 0.50 17.60 ? 567 MET A CA 1 ATOM 4533 C C . MET A 1 567 ? 55.119 103.543 24.673 1.00 17.36 ? 567 MET A C 1 ATOM 4534 O O . MET A 1 567 ? 53.907 103.403 24.700 1.00 17.17 ? 567 MET A O 1 ATOM 4535 C CB A MET A 1 567 ? 55.030 106.075 24.934 0.50 18.54 ? 567 MET A CB 1 ATOM 4536 C CB B MET A 1 567 ? 54.747 106.064 24.691 0.50 18.31 ? 567 MET A CB 1 ATOM 4537 C CG A MET A 1 567 ? 54.878 105.964 26.439 0.50 19.66 ? 567 MET A CG 1 ATOM 4538 C CG B MET A 1 567 ? 54.505 106.301 26.165 0.50 19.05 ? 567 MET A CG 1 ATOM 4539 S SD A MET A 1 567 ? 54.459 107.469 27.311 0.50 19.66 ? 567 MET A SD 1 ATOM 4540 S SD B MET A 1 567 ? 55.995 106.481 27.145 0.50 19.34 ? 567 MET A SD 1 ATOM 4541 C CE A MET A 1 567 ? 56.095 108.154 27.509 0.50 21.53 ? 567 MET A CE 1 ATOM 4542 C CE B MET A 1 567 ? 56.511 108.108 26.659 0.50 20.22 ? 567 MET A CE 1 ATOM 4543 N N . VAL A 1 568 ? 55.971 102.554 24.924 1.00 16.31 ? 568 VAL A N 1 ATOM 4544 C CA . VAL A 1 568 ? 55.593 101.159 25.125 1.00 15.75 ? 568 VAL A CA 1 ATOM 4545 C C . VAL A 1 568 ? 56.643 100.547 26.090 1.00 16.06 ? 568 VAL A C 1 ATOM 4546 O O . VAL A 1 568 ? 57.838 100.908 26.067 1.00 14.52 ? 568 VAL A O 1 ATOM 4547 C CB . VAL A 1 568 ? 55.557 100.396 23.744 1.00 15.07 ? 568 VAL A CB 1 ATOM 4548 C CG1 . VAL A 1 568 ? 56.953 100.428 23.069 1.00 14.99 ? 568 VAL A CG1 1 ATOM 4549 C CG2 . VAL A 1 568 ? 55.104 98.938 23.900 1.00 13.55 ? 568 VAL A CG2 1 ATOM 4550 N N . GLY A 1 569 ? 56.171 99.652 26.955 1.00 16.18 ? 569 GLY A N 1 ATOM 4551 C CA . GLY A 1 569 ? 57.027 98.849 27.800 1.00 17.24 ? 569 GLY A CA 1 ATOM 4552 C C . GLY A 1 569 ? 56.156 97.780 28.416 1.00 17.87 ? 569 GLY A C 1 ATOM 4553 O O . GLY A 1 569 ? 54.939 97.808 28.241 1.00 17.19 ? 569 GLY A O 1 ATOM 4554 N N . PRO A 1 570 ? 56.769 96.812 29.098 1.00 17.86 ? 570 PRO A N 1 ATOM 4555 C CA . PRO A 1 570 ? 56.005 95.804 29.824 1.00 19.29 ? 570 PRO A CA 1 ATOM 4556 C C . PRO A 1 570 ? 55.750 96.242 31.268 1.00 19.99 ? 570 PRO A C 1 ATOM 4557 O O . PRO A 1 570 ? 56.129 97.372 31.670 1.00 21.32 ? 570 PRO A O 1 ATOM 4558 C CB . PRO A 1 570 ? 56.974 94.610 29.814 1.00 18.04 ? 570 PRO A CB 1 ATOM 4559 C CG . PRO A 1 570 ? 58.287 95.277 30.071 1.00 18.15 ? 570 PRO A CG 1 ATOM 4560 C CD . PRO A 1 570 ? 58.213 96.567 29.215 1.00 18.89 ? 570 PRO A CD 1 ATOM 4561 N N . ASP A 1 571 ? 55.157 95.351 32.057 1.00 20.10 ? 571 ASP A N 1 ATOM 4562 C CA . ASP A 1 571 ? 55.143 95.477 33.531 1.00 19.26 ? 571 ASP A CA 1 ATOM 4563 C C . ASP A 1 571 ? 56.526 95.064 34.104 1.00 19.21 ? 571 ASP A C 1 ATOM 4564 O O . ASP A 1 571 ? 56.896 93.885 34.119 1.00 19.14 ? 571 ASP A O 1 ATOM 4565 C CB . ASP A 1 571 ? 54.036 94.613 34.121 1.00 18.21 ? 571 ASP A CB 1 ATOM 4566 C CG . ASP A 1 571 ? 52.632 95.074 33.683 1.00 20.23 ? 571 ASP A CG 1 ATOM 4567 O OD1 . ASP A 1 571 ? 52.457 96.261 33.279 1.00 19.61 ? 571 ASP A OD1 1 ATOM 4568 O OD2 . ASP A 1 571 ? 51.684 94.252 33.734 1.00 22.17 ? 571 ASP A OD2 1 ATOM 4569 N N . ILE A 1 572 ? 57.292 96.045 34.557 1.00 18.59 ? 572 ILE A N 1 ATOM 4570 C CA . ILE A 1 572 ? 58.639 95.785 35.087 1.00 17.85 ? 572 ILE A CA 1 ATOM 4571 C C . ILE A 1 572 ? 58.530 94.899 36.318 1.00 17.98 ? 572 ILE A C 1 ATOM 4572 O O . ILE A 1 572 ? 57.687 95.156 37.189 1.00 16.81 ? 572 ILE A O 1 ATOM 4573 C CB . ILE A 1 572 ? 59.361 97.096 35.444 1.00 17.39 ? 572 ILE A CB 1 ATOM 4574 C CG1 . ILE A 1 572 ? 59.646 97.909 34.189 1.00 16.80 ? 572 ILE A CG1 1 ATOM 4575 C CG2 . ILE A 1 572 ? 60.659 96.813 36.210 1.00 16.66 ? 572 ILE A CG2 1 ATOM 4576 C CD1 . ILE A 1 572 ? 60.139 99.337 34.523 1.00 15.86 ? 572 ILE A CD1 1 ATOM 4577 N N . CYS A 1 573 ? 59.399 93.878 36.370 1.00 17.75 ? 573 CYS A N 1 ATOM 4578 C CA . CYS A 1 573 ? 59.441 92.846 37.406 1.00 18.32 ? 573 CYS A CA 1 ATOM 4579 C C . CYS A 1 573 ? 58.366 91.747 37.227 1.00 18.72 ? 573 CYS A C 1 ATOM 4580 O O . CYS A 1 573 ? 58.425 90.721 37.910 1.00 18.31 ? 573 CYS A O 1 ATOM 4581 C CB . CYS A 1 573 ? 59.459 93.430 38.833 1.00 18.53 ? 573 CYS A CB 1 ATOM 4582 S SG . CYS A 1 573 ? 60.870 94.545 39.135 1.00 22.50 ? 573 CYS A SG 1 ATOM 4583 N N . GLY A 1 574 ? 57.412 91.947 36.311 1.00 17.70 ? 574 GLY A N 1 ATOM 4584 C CA . GLY A 1 574 ? 56.510 90.886 35.944 1.00 19.26 ? 574 GLY A CA 1 ATOM 4585 C C . GLY A 1 574 ? 55.187 91.005 36.694 1.00 19.87 ? 574 GLY A C 1 ATOM 4586 O O . GLY A 1 574 ? 55.154 91.133 37.910 1.00 21.06 ? 574 GLY A O 1 ATOM 4587 N N . PHE A 1 575 ? 54.099 90.975 35.955 1.00 20.23 ? 575 PHE A N 1 ATOM 4588 C CA . PHE A 1 575 ? 52.759 91.087 36.522 1.00 20.49 ? 575 PHE A CA 1 ATOM 4589 C C . PHE A 1 575 ? 52.460 89.863 37.421 1.00 21.67 ? 575 PHE A C 1 ATOM 4590 O O . PHE A 1 575 ? 52.351 90.005 38.646 1.00 22.87 ? 575 PHE A O 1 ATOM 4591 C CB . PHE A 1 575 ? 51.762 91.216 35.374 1.00 19.60 ? 575 PHE A CB 1 ATOM 4592 C CG . PHE A 1 575 ? 50.310 91.279 35.791 1.00 18.25 ? 575 PHE A CG 1 ATOM 4593 C CD1 . PHE A 1 575 ? 49.771 92.433 36.331 1.00 17.44 ? 575 PHE A CD1 1 ATOM 4594 C CD2 . PHE A 1 575 ? 49.471 90.196 35.557 1.00 20.80 ? 575 PHE A CD2 1 ATOM 4595 C CE1 . PHE A 1 575 ? 48.404 92.501 36.670 1.00 19.10 ? 575 PHE A CE1 1 ATOM 4596 C CE2 . PHE A 1 575 ? 48.103 90.244 35.900 1.00 19.86 ? 575 PHE A CE2 1 ATOM 4597 C CZ . PHE A 1 575 ? 47.579 91.397 36.460 1.00 17.07 ? 575 PHE A CZ 1 ATOM 4598 N N . ALA A 1 576 ? 52.342 88.683 36.815 1.00 20.99 ? 576 ALA A N 1 ATOM 4599 C CA . ALA A 1 576 ? 51.964 87.462 37.499 1.00 21.65 ? 576 ALA A CA 1 ATOM 4600 C C . ALA A 1 576 ? 53.163 86.928 38.221 1.00 22.34 ? 576 ALA A C 1 ATOM 4601 O O . ALA A 1 576 ? 54.301 87.026 37.703 1.00 21.83 ? 576 ALA A O 1 ATOM 4602 C CB . ALA A 1 576 ? 51.448 86.398 36.485 1.00 21.34 ? 576 ALA A CB 1 ATOM 4603 N N . LEU A 1 577 ? 52.903 86.391 39.417 1.00 23.09 ? 577 LEU A N 1 ATOM 4604 C CA . LEU A 1 577 ? 53.889 85.703 40.273 1.00 24.42 ? 577 LEU A CA 1 ATOM 4605 C C . LEU A 1 577 ? 54.656 86.654 41.194 1.00 25.11 ? 577 LEU A C 1 ATOM 4606 O O . LEU A 1 577 ? 54.734 87.855 40.918 1.00 25.40 ? 577 LEU A O 1 ATOM 4607 C CB . LEU A 1 577 ? 54.856 84.841 39.438 1.00 24.12 ? 577 LEU A CB 1 ATOM 4608 C CG . LEU A 1 577 ? 54.504 83.414 39.007 1.00 26.08 ? 577 LEU A CG 1 ATOM 4609 C CD1 . LEU A 1 577 ? 53.055 83.204 38.664 1.00 28.41 ? 577 LEU A CD1 1 ATOM 4610 C CD2 . LEU A 1 577 ? 55.401 82.939 37.882 1.00 25.69 ? 577 LEU A CD2 1 ATOM 4611 N N . ASP A 1 578 ? 55.208 86.105 42.282 1.00 25.29 ? 578 ASP A N 1 ATOM 4612 C CA . ASP A 1 578 ? 56.166 86.789 43.135 1.00 26.55 ? 578 ASP A CA 1 ATOM 4613 C C . ASP A 1 578 ? 57.477 87.021 42.355 1.00 27.05 ? 578 ASP A C 1 ATOM 4614 O O . ASP A 1 578 ? 58.020 86.074 41.777 1.00 27.91 ? 578 ASP A O 1 ATOM 4615 C CB . ASP A 1 578 ? 56.472 85.925 44.364 1.00 26.49 ? 578 ASP A CB 1 ATOM 4616 C CG . ASP A 1 578 ? 55.318 85.915 45.411 1.00 28.36 ? 578 ASP A CG 1 ATOM 4617 O OD1 . ASP A 1 578 ? 54.241 86.529 45.200 1.00 30.38 ? 578 ASP A OD1 1 ATOM 4618 O OD2 . ASP A 1 578 ? 55.501 85.291 46.473 1.00 33.27 ? 578 ASP A OD2 1 ATOM 4619 N N . THR A 1 579 ? 57.996 88.249 42.331 1.00 25.85 ? 579 THR A N 1 ATOM 4620 C CA . THR A 1 579 ? 59.239 88.468 41.611 1.00 26.02 ? 579 THR A CA 1 ATOM 4621 C C . THR A 1 579 ? 60.438 88.101 42.502 1.00 26.13 ? 579 THR A C 1 ATOM 4622 O O . THR A 1 579 ? 60.469 88.470 43.673 1.00 26.25 ? 579 THR A O 1 ATOM 4623 C CB . THR A 1 579 ? 59.347 89.902 41.026 1.00 25.39 ? 579 THR A CB 1 ATOM 4624 O OG1 . THR A 1 579 ? 60.380 89.929 40.023 1.00 27.06 ? 579 THR A OG1 1 ATOM 4625 C CG2 . THR A 1 579 ? 59.660 90.934 42.122 1.00 24.20 ? 579 THR A CG2 1 ATOM 4626 N N . PRO A 1 580 ? 61.400 87.323 41.965 1.00 26.64 ? 580 PRO A N 1 ATOM 4627 C CA . PRO A 1 580 ? 62.644 87.094 42.705 1.00 26.72 ? 580 PRO A CA 1 ATOM 4628 C C . PRO A 1 580 ? 63.414 88.433 42.799 1.00 26.60 ? 580 PRO A C 1 ATOM 4629 O O . PRO A 1 580 ? 63.259 89.264 41.922 1.00 26.96 ? 580 PRO A O 1 ATOM 4630 C CB . PRO A 1 580 ? 63.404 86.108 41.798 1.00 27.06 ? 580 PRO A CB 1 ATOM 4631 C CG . PRO A 1 580 ? 62.348 85.460 40.963 1.00 26.52 ? 580 PRO A CG 1 ATOM 4632 C CD . PRO A 1 580 ? 61.396 86.596 40.684 1.00 26.46 ? 580 PRO A CD 1 ATOM 4633 N N . GLU A 1 581 ? 64.208 88.650 43.841 1.00 25.45 ? 581 GLU A N 1 ATOM 4634 C CA . GLU A 1 581 ? 64.982 89.897 43.968 1.00 24.45 ? 581 GLU A CA 1 ATOM 4635 C C . GLU A 1 581 ? 65.953 90.130 42.796 1.00 23.82 ? 581 GLU A C 1 ATOM 4636 O O . GLU A 1 581 ? 66.069 91.263 42.303 1.00 22.56 ? 581 GLU A O 1 ATOM 4637 C CB . GLU A 1 581 ? 65.757 89.940 45.297 1.00 23.50 ? 581 GLU A CB 1 ATOM 4638 C CG . GLU A 1 581 ? 66.489 91.238 45.592 1.00 23.52 ? 581 GLU A CG 1 ATOM 4639 C CD . GLU A 1 581 ? 67.889 91.338 44.979 1.00 24.75 ? 581 GLU A CD 1 ATOM 4640 O OE1 . GLU A 1 581 ? 68.467 90.306 44.543 1.00 28.27 ? 581 GLU A OE1 1 ATOM 4641 O OE2 . GLU A 1 581 ? 68.441 92.463 44.919 1.00 24.87 ? 581 GLU A OE2 1 ATOM 4642 N N . GLU A 1 582 ? 66.672 89.077 42.388 1.00 23.04 ? 582 GLU A N 1 ATOM 4643 C CA . GLU A 1 582 ? 67.670 89.212 41.337 1.00 22.67 ? 582 GLU A CA 1 ATOM 4644 C C . GLU A 1 582 ? 67.031 89.626 40.014 1.00 21.59 ? 582 GLU A C 1 ATOM 4645 O O . GLU A 1 582 ? 67.531 90.541 39.349 1.00 20.47 ? 582 GLU A O 1 ATOM 4646 C CB . GLU A 1 582 ? 68.474 87.923 41.141 1.00 22.14 ? 582 GLU A CB 1 ATOM 4647 C CG . GLU A 1 582 ? 69.710 88.106 40.197 1.00 23.33 ? 582 GLU A CG 1 ATOM 4648 C CD . GLU A 1 582 ? 70.287 86.773 39.663 1.00 25.71 ? 582 GLU A CD 1 ATOM 4649 O OE1 . GLU A 1 582 ? 69.778 85.687 40.048 1.00 28.46 ? 582 GLU A OE1 1 ATOM 4650 O OE2 . GLU A 1 582 ? 71.248 86.820 38.832 1.00 30.80 ? 582 GLU A OE2 1 ATOM 4651 N N . LEU A 1 583 ? 65.938 88.940 39.645 1.00 20.92 ? 583 LEU A N 1 ATOM 4652 C CA . LEU A 1 583 ? 65.167 89.273 38.443 1.00 20.52 ? 583 LEU A CA 1 ATOM 4653 C C . LEU A 1 583 ? 64.665 90.724 38.471 1.00 20.99 ? 583 LEU A C 1 ATOM 4654 O O . LEU A 1 583 ? 64.889 91.494 37.536 1.00 20.67 ? 583 LEU A O 1 ATOM 4655 C CB . LEU A 1 583 ? 63.958 88.321 38.277 1.00 20.42 ? 583 LEU A CB 1 ATOM 4656 C CG . LEU A 1 583 ? 63.110 88.639 37.042 1.00 19.30 ? 583 LEU A CG 1 ATOM 4657 C CD1 . LEU A 1 583 ? 63.908 88.523 35.749 1.00 16.81 ? 583 LEU A CD1 1 ATOM 4658 C CD2 . LEU A 1 583 ? 61.879 87.738 36.977 1.00 19.74 ? 583 LEU A CD2 1 ATOM 4659 N N . CYS A 1 584 ? 63.965 91.091 39.543 1.00 21.03 ? 584 CYS A N 1 ATOM 4660 C CA . CYS A 1 584 ? 63.444 92.451 39.671 1.00 20.67 ? 584 CYS A CA 1 ATOM 4661 C C . CYS A 1 584 ? 64.569 93.533 39.611 1.00 20.86 ? 584 CYS A C 1 ATOM 4662 O O . CYS A 1 584 ? 64.413 94.581 38.986 1.00 20.75 ? 584 CYS A O 1 ATOM 4663 C CB . CYS A 1 584 ? 62.583 92.565 40.918 1.00 20.51 ? 584 CYS A CB 1 ATOM 4664 S SG . CYS A 1 584 ? 61.581 94.129 41.014 1.00 21.98 ? 584 CYS A SG 1 ATOM 4665 N N . ARG A 1 585 ? 65.724 93.254 40.205 1.00 20.47 ? 585 ARG A N 1 ATOM 4666 C CA . ARG A 1 585 ? 66.838 94.197 40.154 1.00 19.60 ? 585 ARG A CA 1 ATOM 4667 C C . ARG A 1 585 ? 67.343 94.344 38.713 1.00 19.81 ? 585 ARG A C 1 ATOM 4668 O O . ARG A 1 585 ? 67.596 95.463 38.264 1.00 19.95 ? 585 ARG A O 1 ATOM 4669 C CB . ARG A 1 585 ? 67.975 93.741 41.100 1.00 20.35 ? 585 ARG A CB 1 ATOM 4670 C CG . ARG A 1 585 ? 69.245 94.561 40.972 1.00 18.98 ? 585 ARG A CG 1 ATOM 4671 C CD . ARG A 1 585 ? 70.205 94.396 42.175 1.00 19.47 ? 585 ARG A CD 1 ATOM 4672 N NE . ARG A 1 585 ? 70.249 93.024 42.682 1.00 23.05 ? 585 ARG A NE 1 ATOM 4673 C CZ . ARG A 1 585 ? 70.939 92.021 42.130 1.00 23.46 ? 585 ARG A CZ 1 ATOM 4674 N NH1 . ARG A 1 585 ? 71.624 92.213 41.020 1.00 24.44 ? 585 ARG A NH1 1 ATOM 4675 N NH2 . ARG A 1 585 ? 70.897 90.800 42.669 1.00 24.44 ? 585 ARG A NH2 1 ATOM 4676 N N . ARG A 1 586 ? 67.467 93.235 37.975 1.00 19.43 ? 586 ARG A N 1 ATOM 4677 C CA . ARG A 1 586 ? 67.926 93.318 36.561 1.00 19.75 ? 586 ARG A CA 1 ATOM 4678 C C . ARG A 1 586 ? 66.853 93.976 35.705 1.00 19.40 ? 586 ARG A C 1 ATOM 4679 O O . ARG A 1 586 ? 67.161 94.706 34.739 1.00 19.68 ? 586 ARG A O 1 ATOM 4680 C CB . ARG A 1 586 ? 68.322 91.940 35.966 1.00 19.07 ? 586 ARG A CB 1 ATOM 4681 C CG . ARG A 1 586 ? 69.587 91.311 36.546 1.00 18.79 ? 586 ARG A CG 1 ATOM 4682 C CD . ARG A 1 586 ? 70.703 92.292 36.562 1.00 20.27 ? 586 ARG A CD 1 ATOM 4683 N NE . ARG A 1 586 ? 71.997 91.659 36.734 1.00 20.86 ? 586 ARG A NE 1 ATOM 4684 C CZ . ARG A 1 586 ? 73.163 92.295 36.741 1.00 21.94 ? 586 ARG A CZ 1 ATOM 4685 N NH1 . ARG A 1 586 ? 73.211 93.621 36.601 1.00 15.51 ? 586 ARG A NH1 1 ATOM 4686 N NH2 . ARG A 1 586 ? 74.286 91.583 36.893 1.00 19.65 ? 586 ARG A NH2 1 ATOM 4687 N N . TRP A 1 587 ? 65.597 93.734 36.070 1.00 18.53 ? 587 TRP A N 1 ATOM 4688 C CA . TRP A 1 587 ? 64.471 94.294 35.343 1.00 18.26 ? 587 TRP A CA 1 ATOM 4689 C C . TRP A 1 587 ? 64.293 95.790 35.577 1.00 18.35 ? 587 TRP A C 1 ATOM 4690 O O . TRP A 1 587 ? 63.953 96.554 34.647 1.00 18.25 ? 587 TRP A O 1 ATOM 4691 C CB . TRP A 1 587 ? 63.188 93.532 35.692 1.00 18.06 ? 587 TRP A CB 1 ATOM 4692 C CG . TRP A 1 587 ? 62.228 93.432 34.531 1.00 18.59 ? 587 TRP A CG 1 ATOM 4693 C CD1 . TRP A 1 587 ? 62.071 94.340 33.504 1.00 17.07 ? 587 TRP A CD1 1 ATOM 4694 C CD2 . TRP A 1 587 ? 61.326 92.344 34.247 1.00 16.43 ? 587 TRP A CD2 1 ATOM 4695 N NE1 . TRP A 1 587 ? 61.133 93.875 32.610 1.00 15.12 ? 587 TRP A NE1 1 ATOM 4696 C CE2 . TRP A 1 587 ? 60.642 92.670 33.047 1.00 15.87 ? 587 TRP A CE2 1 ATOM 4697 C CE3 . TRP A 1 587 ? 61.021 91.131 34.894 1.00 19.14 ? 587 TRP A CE3 1 ATOM 4698 C CZ2 . TRP A 1 587 ? 59.651 91.830 32.481 1.00 16.12 ? 587 TRP A CZ2 1 ATOM 4699 C CZ3 . TRP A 1 587 ? 60.011 90.292 34.326 1.00 17.06 ? 587 TRP A CZ3 1 ATOM 4700 C CH2 . TRP A 1 587 ? 59.361 90.656 33.130 1.00 17.85 ? 587 TRP A CH2 1 ATOM 4701 N N . MET A 1 588 ? 64.530 96.228 36.807 1.00 18.97 ? 588 MET A N 1 ATOM 4702 C CA . MET A 1 588 ? 64.518 97.679 37.095 1.00 19.40 ? 588 MET A CA 1 ATOM 4703 C C . MET A 1 588 ? 65.638 98.456 36.381 1.00 19.23 ? 588 MET A C 1 ATOM 4704 O O . MET A 1 588 ? 65.411 99.587 35.948 1.00 17.62 ? 588 MET A O 1 ATOM 4705 C CB . MET A 1 588 ? 64.531 97.966 38.606 1.00 19.88 ? 588 MET A CB 1 ATOM 4706 C CG . MET A 1 588 ? 63.175 97.731 39.303 1.00 19.36 ? 588 MET A CG 1 ATOM 4707 S SD . MET A 1 588 ? 61.926 98.938 38.812 1.00 22.11 ? 588 MET A SD 1 ATOM 4708 C CE . MET A 1 588 ? 62.737 100.488 39.199 1.00 21.08 ? 588 MET A CE 1 ATOM 4709 N N . GLN A 1 589 ? 66.829 97.847 36.265 1.00 19.50 ? 589 GLN A N 1 ATOM 4710 C CA . GLN A 1 589 ? 67.986 98.432 35.532 1.00 20.05 ? 589 GLN A CA 1 ATOM 4711 C C . GLN A 1 589 ? 67.661 98.628 34.048 1.00 19.44 ? 589 GLN A C 1 ATOM 4712 O O . GLN A 1 589 ? 67.837 99.724 33.501 1.00 19.06 ? 589 GLN A O 1 ATOM 4713 C CB . GLN A 1 589 ? 69.220 97.536 35.684 1.00 19.56 ? 589 GLN A CB 1 ATOM 4714 C CG . GLN A 1 589 ? 69.773 97.515 37.102 1.00 22.43 ? 589 GLN A CG 1 ATOM 4715 C CD . GLN A 1 589 ? 70.790 96.377 37.364 1.00 22.77 ? 589 GLN A CD 1 ATOM 4716 O OE1 . GLN A 1 589 ? 70.993 95.476 36.532 1.00 20.70 ? 589 GLN A OE1 1 ATOM 4717 N NE2 . GLN A 1 589 ? 71.419 96.427 38.528 1.00 25.79 ? 589 GLN A NE2 1 ATOM 4718 N N . LEU A 1 590 ? 67.186 97.559 33.396 1.00 18.64 ? 590 LEU A N 1 ATOM 4719 C CA . LEU A 1 590 ? 66.648 97.671 32.045 1.00 18.39 ? 590 LEU A CA 1 ATOM 4720 C C . LEU A 1 590 ? 65.417 98.597 31.954 1.00 18.14 ? 590 LEU A C 1 ATOM 4721 O O . LEU A 1 590 ? 65.304 99.405 31.008 1.00 17.29 ? 590 LEU A O 1 ATOM 4722 C CB . LEU A 1 590 ? 66.313 96.276 31.489 1.00 17.67 ? 590 LEU A CB 1 ATOM 4723 C CG . LEU A 1 590 ? 65.719 96.235 30.087 1.00 18.15 ? 590 LEU A CG 1 ATOM 4724 C CD1 . LEU A 1 590 ? 66.649 96.931 29.002 1.00 17.25 ? 590 LEU A CD1 1 ATOM 4725 C CD2 . LEU A 1 590 ? 65.366 94.798 29.707 1.00 18.15 ? 590 LEU A CD2 1 ATOM 4726 N N . GLY A 1 591 ? 64.505 98.450 32.920 1.00 17.81 ? 591 GLY A N 1 ATOM 4727 C CA . GLY A 1 591 ? 63.222 99.174 32.926 1.00 17.84 ? 591 GLY A CA 1 ATOM 4728 C C . GLY A 1 591 ? 63.373 100.692 32.987 1.00 18.01 ? 591 GLY A C 1 ATOM 4729 O O . GLY A 1 591 ? 62.516 101.410 32.491 1.00 17.94 ? 591 GLY A O 1 ATOM 4730 N N . ALA A 1 592 ? 64.466 101.177 33.592 1.00 17.55 ? 592 ALA A N 1 ATOM 4731 C CA . ALA A 1 592 ? 64.792 102.596 33.593 1.00 17.50 ? 592 ALA A CA 1 ATOM 4732 C C . ALA A 1 592 ? 65.025 103.109 32.165 1.00 17.63 ? 592 ALA A C 1 ATOM 4733 O O . ALA A 1 592 ? 64.992 104.293 31.918 1.00 17.37 ? 592 ALA A O 1 ATOM 4734 C CB . ALA A 1 592 ? 66.018 102.879 34.503 1.00 17.92 ? 592 ALA A CB 1 ATOM 4735 N N . PHE A 1 593 ? 65.186 102.199 31.203 1.00 18.47 ? 593 PHE A N 1 ATOM 4736 C CA . PHE A 1 593 ? 65.381 102.582 29.782 1.00 18.65 ? 593 PHE A CA 1 ATOM 4737 C C . PHE A 1 593 ? 64.293 102.146 28.783 1.00 19.62 ? 593 PHE A C 1 ATOM 4738 O O . PHE A 1 593 ? 64.457 102.347 27.566 1.00 20.45 ? 593 PHE A O 1 ATOM 4739 C CB . PHE A 1 593 ? 66.798 102.190 29.340 1.00 18.20 ? 593 PHE A CB 1 ATOM 4740 C CG . PHE A 1 593 ? 67.842 102.803 30.230 1.00 19.67 ? 593 PHE A CG 1 ATOM 4741 C CD1 . PHE A 1 593 ? 68.249 104.130 30.030 1.00 19.73 ? 593 PHE A CD1 1 ATOM 4742 C CD2 . PHE A 1 593 ? 68.335 102.095 31.329 1.00 17.89 ? 593 PHE A CD2 1 ATOM 4743 C CE1 . PHE A 1 593 ? 69.157 104.739 30.893 1.00 18.61 ? 593 PHE A CE1 1 ATOM 4744 C CE2 . PHE A 1 593 ? 69.241 102.698 32.206 1.00 20.48 ? 593 PHE A CE2 1 ATOM 4745 C CZ . PHE A 1 593 ? 69.662 104.013 31.987 1.00 18.63 ? 593 PHE A CZ 1 ATOM 4746 N N . TYR A 1 594 ? 63.181 101.563 29.266 1.00 18.69 ? 594 TYR A N 1 ATOM 4747 C CA . TYR A 1 594 ? 62.029 101.371 28.376 1.00 19.39 ? 594 TYR A CA 1 ATOM 4748 C C . TYR A 1 594 ? 61.463 102.777 28.106 1.00 19.94 ? 594 TYR A C 1 ATOM 4749 O O . TYR A 1 594 ? 61.507 103.623 29.002 1.00 20.82 ? 594 TYR A O 1 ATOM 4750 C CB . TYR A 1 594 ? 60.932 100.533 29.023 1.00 18.27 ? 594 TYR A CB 1 ATOM 4751 C CG . TYR A 1 594 ? 61.237 99.079 29.234 1.00 18.46 ? 594 TYR A CG 1 ATOM 4752 C CD1 . TYR A 1 594 ? 61.737 98.284 28.210 1.00 19.11 ? 594 TYR A CD1 1 ATOM 4753 C CD2 . TYR A 1 594 ? 60.941 98.471 30.447 1.00 18.88 ? 594 TYR A CD2 1 ATOM 4754 C CE1 . TYR A 1 594 ? 61.999 96.905 28.428 1.00 17.75 ? 594 TYR A CE1 1 ATOM 4755 C CE2 . TYR A 1 594 ? 61.167 97.132 30.662 1.00 16.58 ? 594 TYR A CE2 1 ATOM 4756 C CZ . TYR A 1 594 ? 61.701 96.354 29.661 1.00 17.04 ? 594 TYR A CZ 1 ATOM 4757 O OH . TYR A 1 594 ? 61.899 95.012 29.895 1.00 17.67 ? 594 TYR A OH 1 ATOM 4758 N N . PRO A 1 595 ? 60.971 103.044 26.884 1.00 19.80 ? 595 PRO A N 1 ATOM 4759 C CA . PRO A 1 595 ? 60.323 104.353 26.622 1.00 20.25 ? 595 PRO A CA 1 ATOM 4760 C C . PRO A 1 595 ? 59.130 104.621 27.561 1.00 20.60 ? 595 PRO A C 1 ATOM 4761 O O . PRO A 1 595 ? 59.023 105.727 28.113 1.00 21.91 ? 595 PRO A O 1 ATOM 4762 C CB . PRO A 1 595 ? 59.888 104.250 25.162 1.00 20.42 ? 595 PRO A CB 1 ATOM 4763 C CG . PRO A 1 595 ? 60.796 103.176 24.579 1.00 20.18 ? 595 PRO A CG 1 ATOM 4764 C CD . PRO A 1 595 ? 61.007 102.183 25.685 1.00 18.69 ? 595 PRO A CD 1 ATOM 4765 N N . PHE A 1 596 ? 58.296 103.607 27.795 1.00 19.36 ? 596 PHE A N 1 ATOM 4766 C CA . PHE A 1 596 ? 57.302 103.622 28.887 1.00 17.87 ? 596 PHE A CA 1 ATOM 4767 C C . PHE A 1 596 ? 57.809 102.762 30.056 1.00 17.96 ? 596 PHE A C 1 ATOM 4768 O O . PHE A 1 596 ? 57.983 101.562 29.897 1.00 18.18 ? 596 PHE A O 1 ATOM 4769 C CB . PHE A 1 596 ? 55.944 103.120 28.385 1.00 18.27 ? 596 PHE A CB 1 ATOM 4770 C CG . PHE A 1 596 ? 54.904 103.006 29.446 1.00 17.11 ? 596 PHE A CG 1 ATOM 4771 C CD1 . PHE A 1 596 ? 54.453 104.148 30.126 1.00 17.97 ? 596 PHE A CD1 1 ATOM 4772 C CD2 . PHE A 1 596 ? 54.386 101.766 29.796 1.00 17.18 ? 596 PHE A CD2 1 ATOM 4773 C CE1 . PHE A 1 596 ? 53.496 104.062 31.130 1.00 18.34 ? 596 PHE A CE1 1 ATOM 4774 C CE2 . PHE A 1 596 ? 53.398 101.668 30.819 1.00 17.49 ? 596 PHE A CE2 1 ATOM 4775 C CZ . PHE A 1 596 ? 52.953 102.831 31.478 1.00 15.19 ? 596 PHE A CZ 1 ATOM 4776 N N . SER A 1 597 ? 58.045 103.390 31.216 1.00 16.56 ? 597 SER A N 1 ATOM 4777 C CA . SER A 1 597 ? 58.668 102.760 32.368 1.00 17.43 ? 597 SER A CA 1 ATOM 4778 C C . SER A 1 597 ? 57.674 102.647 33.551 1.00 17.63 ? 597 SER A C 1 ATOM 4779 O O . SER A 1 597 ? 57.397 103.631 34.241 1.00 16.44 ? 597 SER A O 1 ATOM 4780 C CB . SER A 1 597 ? 59.930 103.573 32.774 1.00 16.71 ? 597 SER A CB 1 ATOM 4781 O OG . SER A 1 597 ? 60.666 102.907 33.787 1.00 17.09 ? 597 SER A OG 1 ATOM 4782 N N . ARG A 1 598 ? 57.102 101.464 33.734 1.00 18.31 ? 598 ARG A N 1 ATOM 4783 C CA . ARG A 1 598 ? 56.079 101.241 34.782 1.00 18.28 ? 598 ARG A CA 1 ATOM 4784 C C . ARG A 1 598 ? 56.324 99.904 35.453 1.00 18.55 ? 598 ARG A C 1 ATOM 4785 O O . ARG A 1 598 ? 56.481 98.878 34.773 1.00 17.86 ? 598 ARG A O 1 ATOM 4786 C CB . ARG A 1 598 ? 54.649 101.266 34.235 1.00 18.21 ? 598 ARG A CB 1 ATOM 4787 C CG . ARG A 1 598 ? 53.585 100.991 35.359 1.00 17.68 ? 598 ARG A CG 1 ATOM 4788 C CD . ARG A 1 598 ? 52.165 101.140 34.872 1.00 18.89 ? 598 ARG A CD 1 ATOM 4789 N NE . ARG A 1 598 ? 51.747 99.954 34.147 1.00 19.63 ? 598 ARG A NE 1 ATOM 4790 C CZ . ARG A 1 598 ? 50.481 99.618 33.935 1.00 18.69 ? 598 ARG A CZ 1 ATOM 4791 N NH1 . ARG A 1 598 ? 49.471 100.385 34.374 1.00 17.04 ? 598 ARG A NH1 1 ATOM 4792 N NH2 . ARG A 1 598 ? 50.232 98.508 33.278 1.00 17.78 ? 598 ARG A NH2 1 ATOM 4793 N N . ASN A 1 599 ? 56.390 99.921 36.782 1.00 18.44 ? 599 ASN A N 1 ATOM 4794 C CA . ASN A 1 599 ? 56.495 98.701 37.572 1.00 18.41 ? 599 ASN A CA 1 ATOM 4795 C C . ASN A 1 599 ? 55.077 98.466 38.011 1.00 19.01 ? 599 ASN A C 1 ATOM 4796 O O . ASN A 1 599 ? 54.492 99.317 38.684 1.00 19.43 ? 599 ASN A O 1 ATOM 4797 C CB . ASN A 1 599 ? 57.485 98.936 38.734 1.00 19.38 ? 599 ASN A CB 1 ATOM 4798 C CG . ASN A 1 599 ? 57.562 97.787 39.725 1.00 19.30 ? 599 ASN A CG 1 ATOM 4799 O OD1 . ASN A 1 599 ? 56.550 97.169 40.097 1.00 21.45 ? 599 ASN A OD1 1 ATOM 4800 N ND2 . ASN A 1 599 ? 58.773 97.523 40.191 1.00 16.33 ? 599 ASN A ND2 1 ATOM 4801 N N . HIS A 1 600 ? 54.500 97.338 37.571 1.00 18.75 ? 600 HIS A N 1 ATOM 4802 C CA . HIS A 1 600 ? 53.121 96.969 37.851 1.00 18.46 ? 600 HIS A CA 1 ATOM 4803 C C . HIS A 1 600 ? 53.082 95.499 38.270 1.00 19.52 ? 600 HIS A C 1 ATOM 4804 O O . HIS A 1 600 ? 53.947 94.704 37.854 1.00 21.32 ? 600 HIS A O 1 ATOM 4805 C CB . HIS A 1 600 ? 52.260 97.258 36.612 1.00 17.99 ? 600 HIS A CB 1 ATOM 4806 C CG . HIS A 1 600 ? 50.827 96.844 36.735 1.00 17.91 ? 600 HIS A CG 1 ATOM 4807 N ND1 . HIS A 1 600 ? 50.017 97.255 37.765 1.00 19.49 ? 600 HIS A ND1 1 ATOM 4808 C CD2 . HIS A 1 600 ? 50.048 96.083 35.928 1.00 17.95 ? 600 HIS A CD2 1 ATOM 4809 C CE1 . HIS A 1 600 ? 48.806 96.743 37.609 1.00 20.40 ? 600 HIS A CE1 1 ATOM 4810 N NE2 . HIS A 1 600 ? 48.794 96.042 36.491 1.00 19.26 ? 600 HIS A NE2 1 ATOM 4811 N N . ASN A 1 601 ? 52.089 95.128 39.082 1.00 18.75 ? 601 ASN A N 1 ATOM 4812 C CA . ASN A 1 601 ? 52.069 93.845 39.754 1.00 19.15 ? 601 ASN A CA 1 ATOM 4813 C C . ASN A 1 601 ? 50.647 93.295 39.822 1.00 19.22 ? 601 ASN A C 1 ATOM 4814 O O . ASN A 1 601 ? 49.670 94.055 39.881 1.00 20.15 ? 601 ASN A O 1 ATOM 4815 C CB . ASN A 1 601 ? 52.729 94.016 41.142 1.00 18.95 ? 601 ASN A CB 1 ATOM 4816 C CG . ASN A 1 601 ? 52.951 92.722 41.880 1.00 19.70 ? 601 ASN A CG 1 ATOM 4817 O OD1 . ASN A 1 601 ? 52.892 91.622 41.305 1.00 19.85 ? 601 ASN A OD1 1 ATOM 4818 N ND2 . ASN A 1 601 ? 53.231 92.839 43.198 1.00 19.29 ? 601 ASN A ND2 1 ATOM 4819 N N . GLY A 1 602 ? 50.515 91.978 39.734 1.00 19.86 ? 602 GLY A N 1 ATOM 4820 C CA . GLY A 1 602 ? 49.206 91.331 39.796 1.00 20.18 ? 602 GLY A CA 1 ATOM 4821 C C . GLY A 1 602 ? 48.677 91.206 41.210 1.00 21.85 ? 602 GLY A C 1 ATOM 4822 O O . GLY A 1 602 ? 49.383 91.499 42.193 1.00 21.38 ? 602 GLY A O 1 ATOM 4823 N N . GLN A 1 603 ? 47.432 90.757 41.307 1.00 21.83 ? 603 GLN A N 1 ATOM 4824 C CA . GLN A 1 603 ? 46.742 90.623 42.570 1.00 23.95 ? 603 GLN A CA 1 ATOM 4825 C C . GLN A 1 603 ? 47.363 89.562 43.490 1.00 23.88 ? 603 GLN A C 1 ATOM 4826 O O . GLN A 1 603 ? 47.644 88.443 43.067 1.00 23.95 ? 603 GLN A O 1 ATOM 4827 C CB . GLN A 1 603 ? 45.267 90.287 42.281 1.00 23.74 ? 603 GLN A CB 1 ATOM 4828 C CG . GLN A 1 603 ? 44.369 90.212 43.470 1.00 26.79 ? 603 GLN A CG 1 ATOM 4829 C CD . GLN A 1 603 ? 42.923 89.818 43.076 1.00 28.40 ? 603 GLN A CD 1 ATOM 4830 O OE1 . GLN A 1 603 ? 42.711 88.829 42.368 1.00 35.44 ? 603 GLN A OE1 1 ATOM 4831 N NE2 . GLN A 1 603 ? 41.946 90.609 43.508 1.00 32.87 ? 603 GLN A NE2 1 ATOM 4832 N N . GLY A 1 604 ? 47.548 89.912 44.762 1.00 24.32 ? 604 GLY A N 1 ATOM 4833 C CA . GLY A 1 604 ? 47.962 88.933 45.757 1.00 26.05 ? 604 GLY A CA 1 ATOM 4834 C C . GLY A 1 604 ? 49.453 88.694 45.906 1.00 27.37 ? 604 GLY A C 1 ATOM 4835 O O . GLY A 1 604 ? 49.895 88.316 46.982 1.00 29.16 ? 604 GLY A O 1 ATOM 4836 N N . TYR A 1 605 ? 50.243 88.926 44.852 1.00 26.94 ? 605 TYR A N 1 ATOM 4837 C CA . TYR A 1 605 ? 51.674 88.600 44.872 1.00 26.54 ? 605 TYR A CA 1 ATOM 4838 C C . TYR A 1 605 ? 52.413 89.520 45.805 1.00 26.17 ? 605 TYR A C 1 ATOM 4839 O O . TYR A 1 605 ? 51.928 90.611 46.084 1.00 26.08 ? 605 TYR A O 1 ATOM 4840 C CB . TYR A 1 605 ? 52.281 88.666 43.445 1.00 25.98 ? 605 TYR A CB 1 ATOM 4841 C CG . TYR A 1 605 ? 51.484 87.844 42.482 1.00 25.04 ? 605 TYR A CG 1 ATOM 4842 C CD1 . TYR A 1 605 ? 51.363 86.469 42.658 1.00 25.06 ? 605 TYR A CD1 1 ATOM 4843 C CD2 . TYR A 1 605 ? 50.775 88.452 41.431 1.00 25.62 ? 605 TYR A CD2 1 ATOM 4844 C CE1 . TYR A 1 605 ? 50.569 85.693 41.776 1.00 27.81 ? 605 TYR A CE1 1 ATOM 4845 C CE2 . TYR A 1 605 ? 49.985 87.701 40.557 1.00 25.38 ? 605 TYR A CE2 1 ATOM 4846 C CZ . TYR A 1 605 ? 49.890 86.328 40.738 1.00 25.63 ? 605 TYR A CZ 1 ATOM 4847 O OH . TYR A 1 605 ? 49.131 85.598 39.882 1.00 27.39 ? 605 TYR A OH 1 ATOM 4848 N N . LYS A 1 606 ? 53.582 89.085 46.274 1.00 26.62 ? 606 LYS A N 1 ATOM 4849 C CA . LYS A 1 606 ? 54.409 89.922 47.166 1.00 28.51 ? 606 LYS A CA 1 ATOM 4850 C C . LYS A 1 606 ? 54.725 91.278 46.546 1.00 27.61 ? 606 LYS A C 1 ATOM 4851 O O . LYS A 1 606 ? 54.822 91.386 45.312 1.00 26.96 ? 606 LYS A O 1 ATOM 4852 C CB . LYS A 1 606 ? 55.661 89.169 47.626 1.00 28.36 ? 606 LYS A CB 1 ATOM 4853 C CG . LYS A 1 606 ? 56.963 89.408 46.892 1.00 31.74 ? 606 LYS A CG 1 ATOM 4854 C CD . LYS A 1 606 ? 58.134 88.772 47.723 1.00 31.90 ? 606 LYS A CD 1 ATOM 4855 C CE . LYS A 1 606 ? 59.527 89.206 47.210 1.00 38.23 ? 606 LYS A CE 1 ATOM 4856 N NZ . LYS A 1 606 ? 60.560 89.060 48.296 1.00 40.24 ? 606 LYS A NZ 1 ATOM 4857 N N . ASP A 1 607 ? 54.849 92.313 47.390 1.00 27.00 ? 607 ASP A N 1 ATOM 4858 C CA . ASP A 1 607 ? 55.160 93.674 46.916 1.00 26.11 ? 607 ASP A CA 1 ATOM 4859 C C . ASP A 1 607 ? 56.363 93.606 46.009 1.00 24.46 ? 607 ASP A C 1 ATOM 4860 O O . ASP A 1 607 ? 57.304 92.846 46.304 1.00 24.07 ? 607 ASP A O 1 ATOM 4861 C CB . ASP A 1 607 ? 55.541 94.605 48.062 1.00 26.89 ? 607 ASP A CB 1 ATOM 4862 C CG . ASP A 1 607 ? 54.403 94.864 49.038 1.00 30.49 ? 607 ASP A CG 1 ATOM 4863 O OD1 . ASP A 1 607 ? 53.204 94.720 48.668 1.00 30.77 ? 607 ASP A OD1 1 ATOM 4864 O OD2 . ASP A 1 607 ? 54.743 95.235 50.193 1.00 33.09 ? 607 ASP A OD2 1 ATOM 4865 N N . GLN A 1 608 ? 56.345 94.376 44.913 1.00 23.19 ? 608 GLN A N 1 ATOM 4866 C CA . GLN A 1 608 ? 57.558 94.492 44.070 1.00 22.20 ? 608 GLN A CA 1 ATOM 4867 C C . GLN A 1 608 ? 57.961 95.921 43.707 1.00 21.93 ? 608 GLN A C 1 ATOM 4868 O O . GLN A 1 608 ? 58.779 96.097 42.804 1.00 22.21 ? 608 GLN A O 1 ATOM 4869 C CB . GLN A 1 608 ? 57.465 93.614 42.814 1.00 21.91 ? 608 GLN A CB 1 ATOM 4870 C CG . GLN A 1 608 ? 56.447 94.074 41.782 1.00 20.33 ? 608 GLN A CG 1 ATOM 4871 C CD . GLN A 1 608 ? 56.199 93.033 40.688 1.00 20.91 ? 608 GLN A CD 1 ATOM 4872 O OE1 . GLN A 1 608 ? 56.189 91.824 40.945 1.00 23.46 ? 608 GLN A OE1 1 ATOM 4873 N NE2 . GLN A 1 608 ? 56.008 93.497 39.467 1.00 17.92 ? 608 GLN A NE2 1 ATOM 4874 N N . ASP A 1 609 ? 57.383 96.917 44.391 1.00 21.28 ? 609 ASP A N 1 ATOM 4875 C CA . ASP A 1 609 ? 57.810 98.307 44.267 1.00 21.47 ? 609 ASP A CA 1 ATOM 4876 C C . ASP A 1 609 ? 59.252 98.417 44.793 1.00 21.70 ? 609 ASP A C 1 ATOM 4877 O O . ASP A 1 609 ? 59.644 97.662 45.698 1.00 21.47 ? 609 ASP A O 1 ATOM 4878 C CB . ASP A 1 609 ? 56.847 99.264 45.010 1.00 22.51 ? 609 ASP A CB 1 ATOM 4879 C CG . ASP A 1 609 ? 56.709 98.941 46.499 1.00 22.07 ? 609 ASP A CG 1 ATOM 4880 O OD1 . ASP A 1 609 ? 55.924 98.023 46.875 1.00 22.87 ? 609 ASP A OD1 1 ATOM 4881 O OD2 . ASP A 1 609 ? 57.362 99.635 47.292 1.00 21.80 ? 609 ASP A OD2 1 ATOM 4882 N N . PRO A 1 610 ? 60.070 99.304 44.194 1.00 21.51 ? 610 PRO A N 1 ATOM 4883 C CA . PRO A 1 610 ? 61.474 99.304 44.583 1.00 21.73 ? 610 PRO A CA 1 ATOM 4884 C C . PRO A 1 610 ? 61.779 99.431 46.082 1.00 22.22 ? 610 PRO A C 1 ATOM 4885 O O . PRO A 1 610 ? 62.633 98.692 46.576 1.00 21.70 ? 610 PRO A O 1 ATOM 4886 C CB . PRO A 1 610 ? 62.070 100.470 43.761 1.00 22.03 ? 610 PRO A CB 1 ATOM 4887 C CG . PRO A 1 610 ? 61.141 100.525 42.549 1.00 21.32 ? 610 PRO A CG 1 ATOM 4888 C CD . PRO A 1 610 ? 59.797 100.251 43.093 1.00 20.45 ? 610 PRO A CD 1 ATOM 4889 N N . ALA A 1 611 ? 61.111 100.343 46.796 1.00 22.62 ? 611 ALA A N 1 ATOM 4890 C CA . ALA A 1 611 ? 61.421 100.564 48.218 1.00 23.35 ? 611 ALA A CA 1 ATOM 4891 C C . ALA A 1 611 ? 61.024 99.363 49.077 1.00 24.17 ? 611 ALA A C 1 ATOM 4892 O O . ALA A 1 611 ? 61.552 99.199 50.171 1.00 24.31 ? 611 ALA A O 1 ATOM 4893 C CB . ALA A 1 611 ? 60.753 101.834 48.748 1.00 23.46 ? 611 ALA A CB 1 ATOM 4894 N N . SER A 1 612 ? 60.132 98.503 48.567 1.00 23.52 ? 612 SER A N 1 ATOM 4895 C CA . SER A 1 612 ? 59.702 97.349 49.314 1.00 23.77 ? 612 SER A CA 1 ATOM 4896 C C . SER A 1 612 ? 60.849 96.363 49.574 1.00 24.80 ? 612 SER A C 1 ATOM 4897 O O . SER A 1 612 ? 60.764 95.516 50.471 1.00 25.27 ? 612 SER A O 1 ATOM 4898 C CB . SER A 1 612 ? 58.481 96.677 48.642 1.00 23.26 ? 612 SER A CB 1 ATOM 4899 O OG . SER A 1 612 ? 58.864 95.787 47.614 1.00 23.27 ? 612 SER A OG 1 ATOM 4900 N N . PHE A 1 613 ? 61.934 96.487 48.815 1.00 25.40 ? 613 PHE A N 1 ATOM 4901 C CA . PHE A 1 613 ? 63.053 95.565 48.919 1.00 25.97 ? 613 PHE A CA 1 ATOM 4902 C C . PHE A 1 613 ? 64.006 95.988 50.028 1.00 27.46 ? 613 PHE A C 1 ATOM 4903 O O . PHE A 1 613 ? 64.958 95.257 50.353 1.00 27.88 ? 613 PHE A O 1 ATOM 4904 C CB . PHE A 1 613 ? 63.761 95.423 47.556 1.00 24.84 ? 613 PHE A CB 1 ATOM 4905 C CG . PHE A 1 613 ? 62.955 94.641 46.545 1.00 24.48 ? 613 PHE A CG 1 ATOM 4906 C CD1 . PHE A 1 613 ? 63.139 93.265 46.400 1.00 22.61 ? 613 PHE A CD1 1 ATOM 4907 C CD2 . PHE A 1 613 ? 61.984 95.275 45.745 1.00 23.76 ? 613 PHE A CD2 1 ATOM 4908 C CE1 . PHE A 1 613 ? 62.391 92.524 45.481 1.00 20.22 ? 613 PHE A CE1 1 ATOM 4909 C CE2 . PHE A 1 613 ? 61.228 94.528 44.806 1.00 21.29 ? 613 PHE A CE2 1 ATOM 4910 C CZ . PHE A 1 613 ? 61.427 93.159 44.687 1.00 21.43 ? 613 PHE A CZ 1 ATOM 4911 N N . GLY A 1 614 ? 63.743 97.163 50.617 1.00 28.44 ? 614 GLY A N 1 ATOM 4912 C CA . GLY A 1 614 ? 64.511 97.637 51.780 1.00 29.70 ? 614 GLY A CA 1 ATOM 4913 C C . GLY A 1 614 ? 65.195 98.956 51.500 1.00 30.49 ? 614 GLY A C 1 ATOM 4914 O O . GLY A 1 614 ? 65.747 99.149 50.420 1.00 31.09 ? 614 GLY A O 1 ATOM 4915 N N . ALA A 1 615 ? 65.186 99.860 52.476 1.00 31.25 ? 615 ALA A N 1 ATOM 4916 C CA . ALA A 1 615 ? 65.665 101.240 52.271 1.00 31.45 ? 615 ALA A CA 1 ATOM 4917 C C . ALA A 1 615 ? 67.146 101.308 51.985 1.00 31.67 ? 615 ALA A C 1 ATOM 4918 O O . ALA A 1 615 ? 67.646 102.318 51.489 1.00 31.83 ? 615 ALA A O 1 ATOM 4919 C CB . ALA A 1 615 ? 65.303 102.132 53.453 1.00 32.18 ? 615 ALA A CB 1 ATOM 4920 N N . ASP A 1 616 ? 67.860 100.236 52.283 1.00 31.73 ? 616 ASP A N 1 ATOM 4921 C CA . ASP A 1 616 ? 69.285 100.220 51.992 1.00 32.41 ? 616 ASP A CA 1 ATOM 4922 C C . ASP A 1 616 ? 69.687 99.068 51.079 1.00 30.56 ? 616 ASP A C 1 ATOM 4923 O O . ASP A 1 616 ? 70.859 98.736 50.967 1.00 31.17 ? 616 ASP A O 1 ATOM 4924 C CB . ASP A 1 616 ? 70.107 100.294 53.301 1.00 34.31 ? 616 ASP A CB 1 ATOM 4925 C CG . ASP A 1 616 ? 69.727 101.543 54.162 1.00 40.49 ? 616 ASP A CG 1 ATOM 4926 O OD1 . ASP A 1 616 ? 69.445 101.390 55.391 1.00 47.83 ? 616 ASP A OD1 1 ATOM 4927 O OD2 . ASP A 1 616 ? 69.672 102.687 53.602 1.00 45.81 ? 616 ASP A OD2 1 ATOM 4928 N N . SER A 1 617 ? 68.706 98.510 50.369 1.00 29.04 ? 617 SER A N 1 ATOM 4929 C CA . SER A 1 617 ? 68.928 97.345 49.528 1.00 26.59 ? 617 SER A CA 1 ATOM 4930 C C . SER A 1 617 ? 69.639 97.702 48.215 1.00 25.63 ? 617 SER A C 1 ATOM 4931 O O . SER A 1 617 ? 69.470 98.804 47.689 1.00 25.85 ? 617 SER A O 1 ATOM 4932 C CB . SER A 1 617 ? 67.606 96.659 49.225 1.00 25.68 ? 617 SER A CB 1 ATOM 4933 O OG . SER A 1 617 ? 66.796 97.473 48.383 1.00 23.77 ? 617 SER A OG 1 ATOM 4934 N N . LEU A 1 618 ? 70.391 96.746 47.684 1.00 24.45 ? 618 LEU A N 1 ATOM 4935 C CA . LEU A 1 618 ? 70.999 96.881 46.393 1.00 24.38 ? 618 LEU A CA 1 ATOM 4936 C C . LEU A 1 618 ? 69.952 97.186 45.313 1.00 24.00 ? 618 LEU A C 1 ATOM 4937 O O . LEU A 1 618 ? 70.233 97.978 44.409 1.00 24.37 ? 618 LEU A O 1 ATOM 4938 C CB . LEU A 1 618 ? 71.836 95.650 46.017 1.00 24.09 ? 618 LEU A CB 1 ATOM 4939 C CG . LEU A 1 618 ? 72.677 95.859 44.746 1.00 24.75 ? 618 LEU A CG 1 ATOM 4940 C CD1 . LEU A 1 618 ? 73.812 96.863 45.009 1.00 28.89 ? 618 LEU A CD1 1 ATOM 4941 C CD2 . LEU A 1 618 ? 73.234 94.564 44.260 1.00 24.80 ? 618 LEU A CD2 1 ATOM 4942 N N . LEU A 1 619 ? 68.773 96.561 45.381 1.00 21.80 ? 619 LEU A N 1 ATOM 4943 C CA . LEU A 1 619 ? 67.795 96.760 44.332 1.00 21.13 ? 619 LEU A CA 1 ATOM 4944 C C . LEU A 1 619 ? 67.351 98.223 44.327 1.00 21.32 ? 619 LEU A C 1 ATOM 4945 O O . LEU A 1 619 ? 67.250 98.838 43.270 1.00 21.19 ? 619 LEU A O 1 ATOM 4946 C CB . LEU A 1 619 ? 66.583 95.790 44.467 1.00 21.30 ? 619 LEU A CB 1 ATOM 4947 C CG . LEU A 1 619 ? 65.445 95.939 43.433 1.00 20.31 ? 619 LEU A CG 1 ATOM 4948 C CD1 . LEU A 1 619 ? 64.704 94.612 43.248 1.00 19.89 ? 619 LEU A CD1 1 ATOM 4949 C CD2 . LEU A 1 619 ? 64.465 97.074 43.762 1.00 20.11 ? 619 LEU A CD2 1 ATOM 4950 N N . LEU A 1 620 ? 67.061 98.778 45.507 1.00 21.98 ? 620 LEU A N 1 ATOM 4951 C CA . LEU A 1 620 ? 66.605 100.154 45.606 1.00 21.14 ? 620 LEU A CA 1 ATOM 4952 C C . LEU A 1 620 ? 67.689 101.129 45.178 1.00 21.86 ? 620 LEU A C 1 ATOM 4953 O O . LEU A 1 620 ? 67.416 102.106 44.459 1.00 22.49 ? 620 LEU A O 1 ATOM 4954 C CB . LEU A 1 620 ? 66.120 100.480 47.027 1.00 21.55 ? 620 LEU A CB 1 ATOM 4955 C CG . LEU A 1 620 ? 65.651 101.923 47.233 1.00 21.53 ? 620 LEU A CG 1 ATOM 4956 C CD1 . LEU A 1 620 ? 64.444 102.296 46.327 1.00 20.46 ? 620 LEU A CD1 1 ATOM 4957 C CD2 . LEU A 1 620 ? 65.361 102.254 48.674 1.00 20.90 ? 620 LEU A CD2 1 ATOM 4958 N N . ASN A 1 621 ? 68.903 100.901 45.641 1.00 21.96 ? 621 ASN A N 1 ATOM 4959 C CA . ASN A 1 621 ? 70.032 101.756 45.293 1.00 23.20 ? 621 ASN A CA 1 ATOM 4960 C C . ASN A 1 621 ? 70.280 101.754 43.796 1.00 23.03 ? 621 ASN A C 1 ATOM 4961 O O . ASN A 1 621 ? 70.425 102.821 43.175 1.00 23.13 ? 621 ASN A O 1 ATOM 4962 C CB . ASN A 1 621 ? 71.306 101.304 46.032 1.00 24.58 ? 621 ASN A CB 1 ATOM 4963 C CG . ASN A 1 621 ? 71.250 101.626 47.533 1.00 29.32 ? 621 ASN A CG 1 ATOM 4964 O OD1 . ASN A 1 621 ? 70.416 102.439 47.966 1.00 34.23 ? 621 ASN A OD1 1 ATOM 4965 N ND2 . ASN A 1 621 ? 72.155 101.028 48.325 1.00 31.60 ? 621 ASN A ND2 1 ATOM 4966 N N . SER A 1 622 ? 70.319 100.554 43.220 1.00 22.52 ? 622 SER A N 1 ATOM 4967 C CA . SER A 1 622 ? 70.467 100.394 41.764 1.00 23.17 ? 622 SER A CA 1 ATOM 4968 C C . SER A 1 622 ? 69.309 101.002 40.951 1.00 23.02 ? 622 SER A C 1 ATOM 4969 O O . SER A 1 622 ? 69.568 101.730 39.993 1.00 23.63 ? 622 SER A O 1 ATOM 4970 C CB . SER A 1 622 ? 70.668 98.937 41.387 1.00 23.01 ? 622 SER A CB 1 ATOM 4971 O OG . SER A 1 622 ? 71.077 98.887 40.046 1.00 24.90 ? 622 SER A OG 1 ATOM 4972 N N . SER A 1 623 ? 68.065 100.738 41.358 1.00 22.24 ? 623 SER A N 1 ATOM 4973 C CA . SER A 1 623 ? 66.884 101.368 40.745 1.00 23.05 ? 623 SER A CA 1 ATOM 4974 C C . SER A 1 623 ? 66.947 102.887 40.800 1.00 22.57 ? 623 SER A C 1 ATOM 4975 O O . SER A 1 623 ? 66.645 103.545 39.819 1.00 22.91 ? 623 SER A O 1 ATOM 4976 C CB . SER A 1 623 ? 65.560 100.938 41.439 1.00 23.33 ? 623 SER A CB 1 ATOM 4977 O OG . SER A 1 623 ? 65.416 99.534 41.474 1.00 24.80 ? 623 SER A OG 1 ATOM 4978 N N . ARG A 1 624 ? 67.319 103.453 41.950 1.00 22.21 ? 624 ARG A N 1 ATOM 4979 C CA . ARG A 1 624 ? 67.415 104.907 42.051 1.00 21.69 ? 624 ARG A CA 1 ATOM 4980 C C . ARG A 1 624 ? 68.508 105.433 41.144 1.00 20.42 ? 624 ARG A C 1 ATOM 4981 O O . ARG A 1 624 ? 68.322 106.435 40.491 1.00 20.05 ? 624 ARG A O 1 ATOM 4982 C CB . ARG A 1 624 ? 67.637 105.391 43.502 1.00 21.12 ? 624 ARG A CB 1 ATOM 4983 C CG . ARG A 1 624 ? 67.594 106.942 43.668 1.00 22.29 ? 624 ARG A CG 1 ATOM 4984 C CD . ARG A 1 624 ? 67.828 107.388 45.134 1.00 26.06 ? 624 ARG A CD 1 ATOM 4985 N NE . ARG A 1 624 ? 68.767 106.485 45.778 1.00 31.40 ? 624 ARG A NE 1 ATOM 4986 C CZ . ARG A 1 624 ? 68.523 105.761 46.857 1.00 31.24 ? 624 ARG A CZ 1 ATOM 4987 N NH1 . ARG A 1 624 ? 67.389 105.863 47.520 1.00 30.25 ? 624 ARG A NH1 1 ATOM 4988 N NH2 . ARG A 1 624 ? 69.468 104.955 47.300 1.00 33.29 ? 624 ARG A NH2 1 ATOM 4989 N N . HIS A 1 625 ? 69.652 104.764 41.132 1.00 19.77 ? 625 HIS A N 1 ATOM 4990 C CA . HIS A 1 625 ? 70.782 105.177 40.303 1.00 19.70 ? 625 HIS A CA 1 ATOM 4991 C C . HIS A 1 625 ? 70.439 105.315 38.797 1.00 17.95 ? 625 HIS A C 1 ATOM 4992 O O . HIS A 1 625 ? 70.761 106.313 38.170 1.00 16.83 ? 625 HIS A O 1 ATOM 4993 C CB . HIS A 1 625 ? 71.919 104.163 40.467 1.00 19.87 ? 625 HIS A CB 1 ATOM 4994 C CG . HIS A 1 625 ? 73.200 104.599 39.817 1.00 24.84 ? 625 HIS A CG 1 ATOM 4995 N ND1 . HIS A 1 625 ? 73.682 104.026 38.661 1.00 26.51 ? 625 HIS A ND1 1 ATOM 4996 C CD2 . HIS A 1 625 ? 74.080 105.570 40.149 1.00 22.99 ? 625 HIS A CD2 1 ATOM 4997 C CE1 . HIS A 1 625 ? 74.805 104.616 38.315 1.00 22.16 ? 625 HIS A CE1 1 ATOM 4998 N NE2 . HIS A 1 625 ? 75.075 105.547 39.207 1.00 26.52 ? 625 HIS A NE2 1 ATOM 4999 N N . TYR A 1 626 ? 69.777 104.300 38.233 1.00 17.55 ? 626 TYR A N 1 ATOM 5000 C CA . TYR A 1 626 ? 69.498 104.248 36.792 1.00 16.38 ? 626 TYR A CA 1 ATOM 5001 C C . TYR A 1 626 ? 68.270 105.058 36.417 1.00 16.70 ? 626 TYR A C 1 ATOM 5002 O O . TYR A 1 626 ? 68.192 105.611 35.320 1.00 16.69 ? 626 TYR A O 1 ATOM 5003 C CB . TYR A 1 626 ? 69.434 102.778 36.305 1.00 17.56 ? 626 TYR A CB 1 ATOM 5004 C CG . TYR A 1 626 ? 70.847 102.232 36.193 1.00 16.04 ? 626 TYR A CG 1 ATOM 5005 C CD1 . TYR A 1 626 ? 71.303 101.233 37.059 1.00 17.78 ? 626 TYR A CD1 1 ATOM 5006 C CD2 . TYR A 1 626 ? 71.752 102.791 35.276 1.00 18.69 ? 626 TYR A CD2 1 ATOM 5007 C CE1 . TYR A 1 626 ? 72.613 100.742 36.973 1.00 18.72 ? 626 TYR A CE1 1 ATOM 5008 C CE2 . TYR A 1 626 ? 73.092 102.322 35.185 1.00 16.67 ? 626 TYR A CE2 1 ATOM 5009 C CZ . TYR A 1 626 ? 73.502 101.319 36.048 1.00 17.03 ? 626 TYR A CZ 1 ATOM 5010 O OH . TYR A 1 626 ? 74.760 100.823 35.967 1.00 19.30 ? 626 TYR A OH 1 ATOM 5011 N N . LEU A 1 627 ? 67.312 105.149 37.339 1.00 17.11 ? 627 LEU A N 1 ATOM 5012 C CA . LEU A 1 627 ? 66.188 106.087 37.157 1.00 16.81 ? 627 LEU A CA 1 ATOM 5013 C C . LEU A 1 627 ? 66.704 107.505 37.193 1.00 17.78 ? 627 LEU A C 1 ATOM 5014 O O . LEU A 1 627 ? 66.222 108.334 36.453 1.00 18.58 ? 627 LEU A O 1 ATOM 5015 C CB . LEU A 1 627 ? 65.109 105.820 38.215 1.00 17.20 ? 627 LEU A CB 1 ATOM 5016 C CG . LEU A 1 627 ? 64.231 104.590 37.927 1.00 16.59 ? 627 LEU A CG 1 ATOM 5017 C CD1 . LEU A 1 627 ? 63.168 104.509 39.024 1.00 16.73 ? 627 LEU A CD1 1 ATOM 5018 C CD2 . LEU A 1 627 ? 63.572 104.775 36.565 1.00 18.31 ? 627 LEU A CD2 1 ATOM 5019 N N . ASN A 1 628 ? 67.719 107.802 38.019 1.00 18.31 ? 628 ASN A N 1 ATOM 5020 C CA . ASN A 1 628 ? 68.332 109.148 37.963 1.00 18.78 ? 628 ASN A CA 1 ATOM 5021 C C . ASN A 1 628 ? 69.067 109.446 36.639 1.00 18.24 ? 628 ASN A C 1 ATOM 5022 O O . ASN A 1 628 ? 69.037 110.576 36.146 1.00 18.95 ? 628 ASN A O 1 ATOM 5023 C CB . ASN A 1 628 ? 69.305 109.361 39.133 1.00 19.59 ? 628 ASN A CB 1 ATOM 5024 C CG . ASN A 1 628 ? 68.630 109.913 40.373 1.00 22.98 ? 628 ASN A CG 1 ATOM 5025 O OD1 . ASN A 1 628 ? 68.976 109.513 41.507 1.00 25.94 ? 628 ASN A OD1 1 ATOM 5026 N ND2 . ASN A 1 628 ? 67.680 110.837 40.186 1.00 20.39 ? 628 ASN A ND2 1 ATOM 5027 N N . ILE A 1 629 ? 69.781 108.447 36.101 1.00 18.16 ? 629 ILE A N 1 ATOM 5028 C CA . ILE A 1 629 ? 70.314 108.534 34.739 1.00 16.61 ? 629 ILE A CA 1 ATOM 5029 C C . ILE A 1 629 ? 69.199 108.735 33.687 1.00 16.72 ? 629 ILE A C 1 ATOM 5030 O O . ILE A 1 629 ? 69.294 109.618 32.842 1.00 15.76 ? 629 ILE A O 1 ATOM 5031 C CB . ILE A 1 629 ? 71.226 107.343 34.400 1.00 17.08 ? 629 ILE A CB 1 ATOM 5032 C CG1 . ILE A 1 629 ? 72.487 107.404 35.277 1.00 16.24 ? 629 ILE A CG1 1 ATOM 5033 C CG2 . ILE A 1 629 ? 71.636 107.376 32.875 1.00 16.07 ? 629 ILE A CG2 1 ATOM 5034 C CD1 . ILE A 1 629 ? 73.213 106.095 35.314 1.00 17.18 ? 629 ILE A CD1 1 ATOM 5035 N N . ARG A 1 630 ? 68.127 107.922 33.741 1.00 16.19 ? 630 ARG A N 1 ATOM 5036 C CA . ARG A 1 630 ? 66.999 108.137 32.823 1.00 15.33 ? 630 ARG A CA 1 ATOM 5037 C C . ARG A 1 630 ? 66.539 109.578 32.893 1.00 16.47 ? 630 ARG A C 1 ATOM 5038 O O . ARG A 1 630 ? 66.370 110.253 31.871 1.00 16.14 ? 630 ARG A O 1 ATOM 5039 C CB . ARG A 1 630 ? 65.818 107.234 33.222 1.00 15.97 ? 630 ARG A CB 1 ATOM 5040 C CG . ARG A 1 630 ? 64.542 107.536 32.411 1.00 14.00 ? 630 ARG A CG 1 ATOM 5041 C CD . ARG A 1 630 ? 63.289 106.887 33.035 1.00 16.38 ? 630 ARG A CD 1 ATOM 5042 N NE . ARG A 1 630 ? 62.150 107.039 32.137 1.00 14.88 ? 630 ARG A NE 1 ATOM 5043 C CZ . ARG A 1 630 ? 61.899 106.250 31.090 1.00 16.07 ? 630 ARG A CZ 1 ATOM 5044 N NH1 . ARG A 1 630 ? 62.721 105.220 30.777 1.00 14.08 ? 630 ARG A NH1 1 ATOM 5045 N NH2 . ARG A 1 630 ? 60.814 106.500 30.348 1.00 15.59 ? 630 ARG A NH2 1 ATOM 5046 N N . TYR A 1 631 ? 66.324 110.074 34.112 1.00 16.82 ? 631 TYR A N 1 ATOM 5047 C CA . TYR A 1 631 ? 65.823 111.446 34.262 1.00 17.29 ? 631 TYR A CA 1 ATOM 5048 C C . TYR A 1 631 ? 66.866 112.464 33.785 1.00 17.23 ? 631 TYR A C 1 ATOM 5049 O O . TYR A 1 631 ? 66.531 113.483 33.141 1.00 16.21 ? 631 TYR A O 1 ATOM 5050 C CB . TYR A 1 631 ? 65.385 111.702 35.708 1.00 17.64 ? 631 TYR A CB 1 ATOM 5051 C CG . TYR A 1 631 ? 63.969 111.271 36.061 1.00 19.52 ? 631 TYR A CG 1 ATOM 5052 C CD1 . TYR A 1 631 ? 63.504 109.981 35.808 1.00 17.87 ? 631 TYR A CD1 1 ATOM 5053 C CD2 . TYR A 1 631 ? 63.092 112.163 36.692 1.00 19.73 ? 631 TYR A CD2 1 ATOM 5054 C CE1 . TYR A 1 631 ? 62.170 109.597 36.179 1.00 17.20 ? 631 TYR A CE1 1 ATOM 5055 C CE2 . TYR A 1 631 ? 61.794 111.781 37.072 1.00 19.11 ? 631 TYR A CE2 1 ATOM 5056 C CZ . TYR A 1 631 ? 61.334 110.510 36.803 1.00 18.08 ? 631 TYR A CZ 1 ATOM 5057 O OH . TYR A 1 631 ? 60.028 110.154 37.195 1.00 16.82 ? 631 TYR A OH 1 ATOM 5058 N N . THR A 1 632 ? 68.148 112.167 34.009 1.00 17.71 ? 632 THR A N 1 ATOM 5059 C CA . THR A 1 632 ? 69.166 113.081 33.480 1.00 17.65 ? 632 THR A CA 1 ATOM 5060 C C . THR A 1 632 ? 69.026 113.263 31.968 1.00 18.72 ? 632 THR A C 1 ATOM 5061 O O . THR A 1 632 ? 69.224 114.352 31.448 1.00 19.28 ? 632 THR A O 1 ATOM 5062 C CB . THR A 1 632 ? 70.561 112.569 33.851 1.00 18.50 ? 632 THR A CB 1 ATOM 5063 O OG1 . THR A 1 632 ? 70.659 112.571 35.273 1.00 17.24 ? 632 THR A OG1 1 ATOM 5064 C CG2 . THR A 1 632 ? 71.671 113.440 33.253 1.00 17.10 ? 632 THR A CG2 1 ATOM 5065 N N . LEU A 1 633 ? 68.672 112.185 31.270 1.00 18.75 ? 633 LEU A N 1 ATOM 5066 C CA . LEU A 1 633 ? 68.660 112.140 29.810 1.00 19.30 ? 633 LEU A CA 1 ATOM 5067 C C . LEU A 1 633 ? 67.257 112.370 29.281 1.00 19.78 ? 633 LEU A C 1 ATOM 5068 O O . LEU A 1 633 ? 67.018 112.208 28.095 1.00 20.30 ? 633 LEU A O 1 ATOM 5069 C CB . LEU A 1 633 ? 69.137 110.766 29.319 1.00 19.20 ? 633 LEU A CB 1 ATOM 5070 C CG . LEU A 1 633 ? 70.631 110.489 29.510 1.00 18.97 ? 633 LEU A CG 1 ATOM 5071 C CD1 . LEU A 1 633 ? 70.930 109.000 29.349 1.00 19.40 ? 633 LEU A CD1 1 ATOM 5072 C CD2 . LEU A 1 633 ? 71.400 111.313 28.454 1.00 21.08 ? 633 LEU A CD2 1 ATOM 5073 N N . LEU A 1 634 ? 66.329 112.752 30.151 1.00 19.36 ? 634 LEU A N 1 ATOM 5074 C CA . LEU A 1 634 ? 64.988 113.077 29.658 1.00 19.83 ? 634 LEU A CA 1 ATOM 5075 C C . LEU A 1 634 ? 64.948 114.136 28.547 1.00 18.86 ? 634 LEU A C 1 ATOM 5076 O O . LEU A 1 634 ? 64.169 114.000 27.624 1.00 19.99 ? 634 LEU A O 1 ATOM 5077 C CB . LEU A 1 634 ? 64.025 113.421 30.803 1.00 19.64 ? 634 LEU A CB 1 ATOM 5078 C CG . LEU A 1 634 ? 63.339 112.260 31.518 1.00 22.01 ? 634 LEU A CG 1 ATOM 5079 C CD1 . LEU A 1 634 ? 62.144 112.772 32.308 1.00 23.64 ? 634 LEU A CD1 1 ATOM 5080 C CD2 . LEU A 1 634 ? 62.908 111.169 30.613 1.00 20.73 ? 634 LEU A CD2 1 ATOM 5081 N N . PRO A 1 635 ? 65.751 115.223 28.618 1.00 18.48 ? 635 PRO A N 1 ATOM 5082 C CA . PRO A 1 635 ? 65.700 116.072 27.401 1.00 17.53 ? 635 PRO A CA 1 ATOM 5083 C C . PRO A 1 635 ? 66.085 115.413 26.053 1.00 16.70 ? 635 PRO A C 1 ATOM 5084 O O . PRO A 1 635 ? 65.539 115.793 25.042 1.00 16.91 ? 635 PRO A O 1 ATOM 5085 C CB . PRO A 1 635 ? 66.675 117.220 27.734 1.00 18.16 ? 635 PRO A CB 1 ATOM 5086 C CG . PRO A 1 635 ? 66.576 117.299 29.270 1.00 18.05 ? 635 PRO A CG 1 ATOM 5087 C CD . PRO A 1 635 ? 66.588 115.838 29.666 1.00 18.29 ? 635 PRO A CD 1 ATOM 5088 N N . TYR A 1 636 ? 67.048 114.497 26.065 1.00 15.24 ? 636 TYR A N 1 ATOM 5089 C CA . TYR A 1 636 ? 67.400 113.641 24.932 1.00 15.07 ? 636 TYR A CA 1 ATOM 5090 C C . TYR A 1 636 ? 66.220 112.683 24.561 1.00 14.32 ? 636 TYR A C 1 ATOM 5091 O O . TYR A 1 636 ? 65.783 112.659 23.430 1.00 13.33 ? 636 TYR A O 1 ATOM 5092 C CB . TYR A 1 636 ? 68.706 112.833 25.272 1.00 14.61 ? 636 TYR A CB 1 ATOM 5093 C CG . TYR A 1 636 ? 69.118 111.850 24.179 1.00 15.94 ? 636 TYR A CG 1 ATOM 5094 C CD1 . TYR A 1 636 ? 69.609 112.302 22.939 1.00 16.08 ? 636 TYR A CD1 1 ATOM 5095 C CD2 . TYR A 1 636 ? 69.028 110.475 24.387 1.00 15.76 ? 636 TYR A CD2 1 ATOM 5096 C CE1 . TYR A 1 636 ? 69.948 111.403 21.914 1.00 14.46 ? 636 TYR A CE1 1 ATOM 5097 C CE2 . TYR A 1 636 ? 69.392 109.578 23.394 1.00 14.57 ? 636 TYR A CE2 1 ATOM 5098 C CZ . TYR A 1 636 ? 69.833 110.037 22.157 1.00 15.70 ? 636 TYR A CZ 1 ATOM 5099 O OH . TYR A 1 636 ? 70.154 109.089 21.191 1.00 15.97 ? 636 TYR A OH 1 ATOM 5100 N N . LEU A 1 637 ? 65.693 111.922 25.526 1.00 15.38 ? 637 LEU A N 1 ATOM 5101 C CA . LEU A 1 637 ? 64.503 111.060 25.266 1.00 14.69 ? 637 LEU A CA 1 ATOM 5102 C C . LEU A 1 637 ? 63.335 111.871 24.659 1.00 16.00 ? 637 LEU A C 1 ATOM 5103 O O . LEU A 1 637 ? 62.756 111.464 23.658 1.00 16.69 ? 637 LEU A O 1 ATOM 5104 C CB . LEU A 1 637 ? 64.053 110.328 26.543 1.00 15.05 ? 637 LEU A CB 1 ATOM 5105 C CG . LEU A 1 637 ? 62.908 109.314 26.380 1.00 13.78 ? 637 LEU A CG 1 ATOM 5106 C CD1 . LEU A 1 637 ? 63.385 108.229 25.371 1.00 12.01 ? 637 LEU A CD1 1 ATOM 5107 C CD2 . LEU A 1 637 ? 62.558 108.678 27.689 1.00 13.48 ? 637 LEU A CD2 1 ATOM 5108 N N . TYR A 1 638 ? 63.004 113.012 25.263 1.00 16.25 ? 638 TYR A N 1 ATOM 5109 C CA . TYR A 1 638 ? 61.913 113.880 24.812 1.00 16.25 ? 638 TYR A CA 1 ATOM 5110 C C . TYR A 1 638 ? 62.085 114.415 23.396 1.00 16.27 ? 638 TYR A C 1 ATOM 5111 O O . TYR A 1 638 ? 61.114 114.545 22.636 1.00 15.63 ? 638 TYR A O 1 ATOM 5112 C CB . TYR A 1 638 ? 61.818 115.062 25.767 1.00 16.69 ? 638 TYR A CB 1 ATOM 5113 C CG . TYR A 1 638 ? 60.575 115.888 25.624 1.00 19.59 ? 638 TYR A CG 1 ATOM 5114 C CD1 . TYR A 1 638 ? 59.320 115.302 25.772 1.00 19.57 ? 638 TYR A CD1 1 ATOM 5115 C CD2 . TYR A 1 638 ? 60.641 117.271 25.394 1.00 20.33 ? 638 TYR A CD2 1 ATOM 5116 C CE1 . TYR A 1 638 ? 58.182 116.048 25.666 1.00 20.56 ? 638 TYR A CE1 1 ATOM 5117 C CE2 . TYR A 1 638 ? 59.472 118.036 25.279 1.00 19.69 ? 638 TYR A CE2 1 ATOM 5118 C CZ . TYR A 1 638 ? 58.242 117.400 25.424 1.00 19.73 ? 638 TYR A CZ 1 ATOM 5119 O OH . TYR A 1 638 ? 57.031 118.094 25.354 1.00 19.16 ? 638 TYR A OH 1 ATOM 5120 N N . THR A 1 639 ? 63.326 114.745 23.031 1.00 16.68 ? 639 THR A N 1 ATOM 5121 C CA . THR A 1 639 ? 63.634 115.198 21.671 1.00 16.07 ? 639 THR A CA 1 ATOM 5122 C C . THR A 1 639 ? 63.449 114.014 20.690 1.00 16.61 ? 639 THR A C 1 ATOM 5123 O O . THR A 1 639 ? 62.979 114.188 19.557 1.00 16.59 ? 639 THR A O 1 ATOM 5124 C CB . THR A 1 639 ? 65.077 115.821 21.568 1.00 17.16 ? 639 THR A CB 1 ATOM 5125 O OG1 . THR A 1 639 ? 65.220 116.894 22.522 1.00 17.95 ? 639 THR A OG1 1 ATOM 5126 C CG2 . THR A 1 639 ? 65.379 116.330 20.137 1.00 13.80 ? 639 THR A CG2 1 ATOM 5127 N N . LEU A 1 640 ? 63.794 112.803 21.131 1.00 16.52 ? 640 LEU A N 1 ATOM 5128 C CA . LEU A 1 640 ? 63.517 111.612 20.343 1.00 15.30 ? 640 LEU A CA 1 ATOM 5129 C C . LEU A 1 640 ? 62.004 111.445 20.068 1.00 15.62 ? 640 LEU A C 1 ATOM 5130 O O . LEU A 1 640 ? 61.622 111.090 18.941 1.00 16.78 ? 640 LEU A O 1 ATOM 5131 C CB . LEU A 1 640 ? 64.076 110.360 21.022 1.00 14.27 ? 640 LEU A CB 1 ATOM 5132 C CG . LEU A 1 640 ? 65.616 110.252 21.087 1.00 12.77 ? 640 LEU A CG 1 ATOM 5133 C CD1 . LEU A 1 640 ? 65.915 108.923 21.693 1.00 13.66 ? 640 LEU A CD1 1 ATOM 5134 C CD2 . LEU A 1 640 ? 66.253 110.371 19.705 1.00 11.05 ? 640 LEU A CD2 1 ATOM 5135 N N . PHE A 1 641 ? 61.171 111.633 21.090 1.00 15.17 ? 641 PHE A N 1 ATOM 5136 C CA . PHE A 1 641 ? 59.688 111.567 20.912 1.00 16.03 ? 641 PHE A CA 1 ATOM 5137 C C . PHE A 1 641 ? 59.191 112.707 20.017 1.00 16.46 ? 641 PHE A C 1 ATOM 5138 O O . PHE A 1 641 ? 58.215 112.552 19.243 1.00 17.24 ? 641 PHE A O 1 ATOM 5139 C CB . PHE A 1 641 ? 58.969 111.627 22.271 1.00 14.94 ? 641 PHE A CB 1 ATOM 5140 C CG . PHE A 1 641 ? 58.854 110.300 22.958 1.00 16.07 ? 641 PHE A CG 1 ATOM 5141 C CD1 . PHE A 1 641 ? 57.892 109.351 22.526 1.00 14.85 ? 641 PHE A CD1 1 ATOM 5142 C CD2 . PHE A 1 641 ? 59.689 109.978 24.028 1.00 14.30 ? 641 PHE A CD2 1 ATOM 5143 C CE1 . PHE A 1 641 ? 57.776 108.136 23.155 1.00 13.29 ? 641 PHE A CE1 1 ATOM 5144 C CE2 . PHE A 1 641 ? 59.581 108.742 24.701 1.00 14.35 ? 641 PHE A CE2 1 ATOM 5145 C CZ . PHE A 1 641 ? 58.620 107.789 24.241 1.00 15.22 ? 641 PHE A CZ 1 ATOM 5146 N N . PHE A 1 642 ? 59.863 113.856 20.099 1.00 16.21 ? 642 PHE A N 1 ATOM 5147 C CA . PHE A 1 642 ? 59.583 114.959 19.157 1.00 17.13 ? 642 PHE A CA 1 ATOM 5148 C C . PHE A 1 642 ? 59.795 114.503 17.715 1.00 16.57 ? 642 PHE A C 1 ATOM 5149 O O . PHE A 1 642 ? 58.950 114.799 16.865 1.00 17.73 ? 642 PHE A O 1 ATOM 5150 C CB . PHE A 1 642 ? 60.407 116.254 19.465 1.00 16.18 ? 642 PHE A CB 1 ATOM 5151 C CG . PHE A 1 642 ? 60.557 117.183 18.280 1.00 17.78 ? 642 PHE A CG 1 ATOM 5152 C CD1 . PHE A 1 642 ? 59.459 117.899 17.787 1.00 16.77 ? 642 PHE A CD1 1 ATOM 5153 C CD2 . PHE A 1 642 ? 61.808 117.361 17.674 1.00 16.01 ? 642 PHE A CD2 1 ATOM 5154 C CE1 . PHE A 1 642 ? 59.594 118.760 16.701 1.00 18.72 ? 642 PHE A CE1 1 ATOM 5155 C CE2 . PHE A 1 642 ? 61.964 118.206 16.605 1.00 16.83 ? 642 PHE A CE2 1 ATOM 5156 C CZ . PHE A 1 642 ? 60.841 118.942 16.114 1.00 18.16 ? 642 PHE A CZ 1 ATOM 5157 N N . ARG A 1 643 ? 60.911 113.813 17.431 1.00 16.46 ? 643 ARG A N 1 ATOM 5158 C CA . ARG A 1 643 ? 61.211 113.348 16.053 1.00 16.22 ? 643 ARG A CA 1 ATOM 5159 C C . ARG A 1 643 ? 60.203 112.265 15.613 1.00 16.52 ? 643 ARG A C 1 ATOM 5160 O O . ARG A 1 643 ? 59.700 112.288 14.496 1.00 17.08 ? 643 ARG A O 1 ATOM 5161 C CB . ARG A 1 643 ? 62.685 112.906 15.905 1.00 16.39 ? 643 ARG A CB 1 ATOM 5162 C CG . ARG A 1 643 ? 63.725 114.051 16.043 1.00 17.70 ? 643 ARG A CG 1 ATOM 5163 C CD . ARG A 1 643 ? 63.501 115.133 14.974 1.00 19.93 ? 643 ARG A CD 1 ATOM 5164 N NE . ARG A 1 643 ? 64.669 116.008 14.863 1.00 25.59 ? 643 ARG A NE 1 ATOM 5165 C CZ . ARG A 1 643 ? 64.750 117.090 14.092 1.00 26.46 ? 643 ARG A CZ 1 ATOM 5166 N NH1 . ARG A 1 643 ? 63.727 117.482 13.334 1.00 27.33 ? 643 ARG A NH1 1 ATOM 5167 N NH2 . ARG A 1 643 ? 65.864 117.793 14.094 1.00 26.81 ? 643 ARG A NH2 1 ATOM 5168 N N . ALA A 1 644 ? 59.813 111.391 16.546 1.00 16.33 ? 644 ALA A N 1 ATOM 5169 C CA . ALA A 1 644 ? 58.797 110.386 16.279 1.00 15.30 ? 644 ALA A CA 1 ATOM 5170 C C . ALA A 1 644 ? 57.473 111.057 15.889 1.00 16.37 ? 644 ALA A C 1 ATOM 5171 O O . ALA A 1 644 ? 56.816 110.678 14.906 1.00 15.53 ? 644 ALA A O 1 ATOM 5172 C CB . ALA A 1 644 ? 58.633 109.477 17.513 1.00 14.88 ? 644 ALA A CB 1 ATOM 5173 N N . HIS A 1 645 ? 57.086 112.056 16.672 1.00 17.28 ? 645 HIS A N 1 ATOM 5174 C CA . HIS A 1 645 ? 55.831 112.780 16.476 1.00 17.54 ? 645 HIS A CA 1 ATOM 5175 C C . HIS A 1 645 ? 55.803 113.599 15.184 1.00 17.98 ? 645 HIS A C 1 ATOM 5176 O O . HIS A 1 645 ? 54.793 113.640 14.472 1.00 17.96 ? 645 HIS A O 1 ATOM 5177 C CB . HIS A 1 645 ? 55.591 113.665 17.713 1.00 18.32 ? 645 HIS A CB 1 ATOM 5178 C CG . HIS A 1 645 ? 54.456 114.636 17.569 1.00 20.50 ? 645 HIS A CG 1 ATOM 5179 N ND1 . HIS A 1 645 ? 53.139 114.232 17.478 1.00 20.20 ? 645 HIS A ND1 1 ATOM 5180 C CD2 . HIS A 1 645 ? 54.441 115.992 17.547 1.00 22.24 ? 645 HIS A CD2 1 ATOM 5181 C CE1 . HIS A 1 645 ? 52.365 115.302 17.373 1.00 25.05 ? 645 HIS A CE1 1 ATOM 5182 N NE2 . HIS A 1 645 ? 53.131 116.383 17.420 1.00 24.84 ? 645 HIS A NE2 1 ATOM 5183 N N . SER A 1 646 ? 56.916 114.246 14.856 1.00 18.47 ? 646 SER A N 1 ATOM 5184 C CA . SER A 1 646 ? 56.952 115.167 13.717 1.00 18.99 ? 646 SER A CA 1 ATOM 5185 C C . SER A 1 646 ? 57.506 114.520 12.430 1.00 19.94 ? 646 SER A C 1 ATOM 5186 O O . SER A 1 646 ? 57.094 114.873 11.334 1.00 20.69 ? 646 SER A O 1 ATOM 5187 C CB . SER A 1 646 ? 57.815 116.384 14.074 1.00 19.16 ? 646 SER A CB 1 ATOM 5188 O OG . SER A 1 646 ? 59.143 115.959 14.288 1.00 20.04 ? 646 SER A OG 1 ATOM 5189 N N . ARG A 1 647 ? 58.430 113.574 12.553 1.00 20.50 ? 647 ARG A N 1 ATOM 5190 C CA . ARG A 1 647 ? 59.076 113.013 11.370 1.00 21.20 ? 647 ARG A CA 1 ATOM 5191 C C . ARG A 1 647 ? 58.809 111.504 11.235 1.00 20.68 ? 647 ARG A C 1 ATOM 5192 O O . ARG A 1 647 ? 58.926 110.950 10.164 1.00 20.84 ? 647 ARG A O 1 ATOM 5193 C CB . ARG A 1 647 ? 60.576 113.337 11.421 1.00 21.60 ? 647 ARG A CB 1 ATOM 5194 C CG . ARG A 1 647 ? 61.433 112.721 10.328 1.00 24.53 ? 647 ARG A CG 1 ATOM 5195 C CD . ARG A 1 647 ? 62.783 113.438 10.287 1.00 24.31 ? 647 ARG A CD 1 ATOM 5196 N NE . ARG A 1 647 ? 63.649 113.001 11.378 1.00 24.77 ? 647 ARG A NE 1 ATOM 5197 C CZ . ARG A 1 647 ? 64.748 113.623 11.789 1.00 22.78 ? 647 ARG A CZ 1 ATOM 5198 N NH1 . ARG A 1 647 ? 65.144 114.746 11.220 1.00 24.77 ? 647 ARG A NH1 1 ATOM 5199 N NH2 . ARG A 1 647 ? 65.457 113.106 12.784 1.00 23.83 ? 647 ARG A NH2 1 ATOM 5200 N N . GLY A 1 648 ? 58.481 110.836 12.324 1.00 19.98 ? 648 GLY A N 1 ATOM 5201 C CA . GLY A 1 648 ? 58.214 109.412 12.261 1.00 21.13 ? 648 GLY A CA 1 ATOM 5202 C C . GLY A 1 648 ? 59.350 108.456 12.605 1.00 21.14 ? 648 GLY A C 1 ATOM 5203 O O . GLY A 1 648 ? 59.239 107.276 12.349 1.00 21.62 ? 648 GLY A O 1 ATOM 5204 N N . ASP A 1 649 ? 60.432 108.966 13.186 1.00 21.00 ? 649 ASP A N 1 ATOM 5205 C CA . ASP A 1 649 ? 61.551 108.174 13.673 1.00 21.01 ? 649 ASP A CA 1 ATOM 5206 C C . ASP A 1 649 ? 61.096 107.198 14.767 1.00 20.91 ? 649 ASP A C 1 ATOM 5207 O O . ASP A 1 649 ? 60.106 107.430 15.421 1.00 22.01 ? 649 ASP A O 1 ATOM 5208 C CB . ASP A 1 649 ? 62.608 109.120 14.301 1.00 21.31 ? 649 ASP A CB 1 ATOM 5209 C CG . ASP A 1 649 ? 63.243 110.120 13.292 1.00 23.00 ? 649 ASP A CG 1 ATOM 5210 O OD1 . ASP A 1 649 ? 62.643 110.479 12.266 1.00 26.09 ? 649 ASP A OD1 1 ATOM 5211 O OD2 . ASP A 1 649 ? 64.391 110.541 13.539 1.00 28.45 ? 649 ASP A OD2 1 ATOM 5212 N N . THR A 1 650 ? 61.883 106.148 15.020 1.00 20.14 ? 650 THR A N 1 ATOM 5213 C CA . THR A 1 650 ? 61.684 105.271 16.186 1.00 18.81 ? 650 THR A CA 1 ATOM 5214 C C . THR A 1 650 ? 62.333 105.932 17.391 1.00 18.54 ? 650 THR A C 1 ATOM 5215 O O . THR A 1 650 ? 63.200 106.783 17.223 1.00 17.99 ? 650 THR A O 1 ATOM 5216 C CB . THR A 1 650 ? 62.334 103.870 15.973 1.00 18.19 ? 650 THR A CB 1 ATOM 5217 O OG1 . THR A 1 650 ? 63.719 104.064 15.638 1.00 17.23 ? 650 THR A OG1 1 ATOM 5218 C CG2 . THR A 1 650 ? 61.603 103.109 14.833 1.00 18.27 ? 650 THR A CG2 1 ATOM 5219 N N . VAL A 1 651 ? 61.956 105.496 18.592 1.00 17.81 ? 651 VAL A N 1 ATOM 5220 C CA . VAL A 1 651 ? 62.567 106.003 19.826 1.00 16.89 ? 651 VAL A CA 1 ATOM 5221 C C . VAL A 1 651 ? 63.513 104.941 20.380 1.00 17.08 ? 651 VAL A C 1 ATOM 5222 O O . VAL A 1 651 ? 64.745 105.137 20.395 1.00 17.02 ? 651 VAL A O 1 ATOM 5223 C CB . VAL A 1 651 ? 61.478 106.479 20.883 1.00 16.81 ? 651 VAL A CB 1 ATOM 5224 C CG1 . VAL A 1 651 ? 62.155 106.924 22.157 1.00 17.30 ? 651 VAL A CG1 1 ATOM 5225 C CG2 . VAL A 1 651 ? 60.646 107.603 20.311 1.00 14.18 ? 651 VAL A CG2 1 ATOM 5226 N N . ALA A 1 652 ? 62.943 103.825 20.843 1.00 17.57 ? 652 ALA A N 1 ATOM 5227 C CA . ALA A 1 652 ? 63.699 102.607 21.118 1.00 16.91 ? 652 ALA A CA 1 ATOM 5228 C C . ALA A 1 652 ? 63.910 101.964 19.732 1.00 17.99 ? 652 ALA A C 1 ATOM 5229 O O . ALA A 1 652 ? 62.917 101.596 19.008 1.00 17.11 ? 652 ALA A O 1 ATOM 5230 C CB . ALA A 1 652 ? 62.947 101.669 22.067 1.00 17.17 ? 652 ALA A CB 1 ATOM 5231 N N . ARG A 1 653 ? 65.192 101.828 19.394 1.00 17.14 ? 653 ARG A N 1 ATOM 5232 C CA . ARG A 1 653 ? 65.674 101.574 18.038 1.00 17.11 ? 653 ARG A CA 1 ATOM 5233 C C . ARG A 1 653 ? 66.564 100.333 18.009 1.00 16.97 ? 653 ARG A C 1 ATOM 5234 O O . ARG A 1 653 ? 67.422 100.185 18.862 1.00 18.69 ? 653 ARG A O 1 ATOM 5235 C CB . ARG A 1 653 ? 66.493 102.794 17.580 1.00 16.27 ? 653 ARG A CB 1 ATOM 5236 C CG . ARG A 1 653 ? 66.752 102.829 16.077 1.00 17.43 ? 653 ARG A CG 1 ATOM 5237 C CD . ARG A 1 653 ? 67.324 104.131 15.644 1.00 17.30 ? 653 ARG A CD 1 ATOM 5238 N NE . ARG A 1 653 ? 66.340 105.202 15.866 1.00 12.04 ? 653 ARG A NE 1 ATOM 5239 C CZ . ARG A 1 653 ? 66.559 106.493 15.639 1.00 16.92 ? 653 ARG A CZ 1 ATOM 5240 N NH1 . ARG A 1 653 ? 67.754 106.932 15.174 1.00 14.78 ? 653 ARG A NH1 1 ATOM 5241 N NH2 . ARG A 1 653 ? 65.596 107.362 15.934 1.00 16.88 ? 653 ARG A NH2 1 ATOM 5242 N N . PRO A 1 654 ? 66.368 99.433 17.018 1.00 17.04 ? 654 PRO A N 1 ATOM 5243 C CA . PRO A 1 654 ? 67.276 98.289 16.826 1.00 15.16 ? 654 PRO A CA 1 ATOM 5244 C C . PRO A 1 654 ? 68.686 98.742 16.414 1.00 15.31 ? 654 PRO A C 1 ATOM 5245 O O . PRO A 1 654 ? 68.839 99.725 15.717 1.00 15.46 ? 654 PRO A O 1 ATOM 5246 C CB . PRO A 1 654 ? 66.605 97.470 15.704 1.00 15.24 ? 654 PRO A CB 1 ATOM 5247 C CG . PRO A 1 654 ? 65.133 98.014 15.646 1.00 16.29 ? 654 PRO A CG 1 ATOM 5248 C CD . PRO A 1 654 ? 65.254 99.456 16.044 1.00 16.59 ? 654 PRO A CD 1 ATOM 5249 N N . LEU A 1 655 ? 69.709 98.022 16.843 1.00 15.20 ? 655 LEU A N 1 ATOM 5250 C CA . LEU A 1 655 ? 71.084 98.309 16.369 1.00 15.68 ? 655 LEU A CA 1 ATOM 5251 C C . LEU A 1 655 ? 71.154 98.374 14.863 1.00 15.27 ? 655 LEU A C 1 ATOM 5252 O O . LEU A 1 655 ? 71.837 99.218 14.312 1.00 14.11 ? 655 LEU A O 1 ATOM 5253 C CB . LEU A 1 655 ? 72.081 97.270 16.907 1.00 14.88 ? 655 LEU A CB 1 ATOM 5254 C CG . LEU A 1 655 ? 72.668 97.574 18.277 1.00 16.58 ? 655 LEU A CG 1 ATOM 5255 C CD1 . LEU A 1 655 ? 71.571 97.792 19.332 1.00 13.47 ? 655 LEU A CD1 1 ATOM 5256 C CD2 . LEU A 1 655 ? 73.725 96.494 18.727 1.00 15.03 ? 655 LEU A CD2 1 ATOM 5257 N N . LEU A 1 656 ? 70.386 97.511 14.201 1.00 15.96 ? 656 LEU A N 1 ATOM 5258 C CA . LEU A 1 656 ? 70.504 97.346 12.736 1.00 16.16 ? 656 LEU A CA 1 ATOM 5259 C C . LEU A 1 656 ? 69.941 98.558 12.006 1.00 16.64 ? 656 LEU A C 1 ATOM 5260 O O . LEU A 1 656 ? 70.218 98.723 10.821 1.00 16.46 ? 656 LEU A O 1 ATOM 5261 C CB . LEU A 1 656 ? 69.783 96.063 12.246 1.00 16.19 ? 656 LEU A CB 1 ATOM 5262 C CG . LEU A 1 656 ? 68.227 96.071 12.275 1.00 17.88 ? 656 LEU A CG 1 ATOM 5263 C CD1 . LEU A 1 656 ? 67.600 96.281 10.863 1.00 17.87 ? 656 LEU A CD1 1 ATOM 5264 C CD2 . LEU A 1 656 ? 67.644 94.807 12.915 1.00 16.56 ? 656 LEU A CD2 1 ATOM 5265 N N . HIS A 1 657 ? 69.131 99.393 12.684 1.00 16.25 ? 657 HIS A N 1 ATOM 5266 C CA . HIS A 1 657 ? 68.665 100.619 12.049 1.00 15.80 ? 657 HIS A CA 1 ATOM 5267 C C . HIS A 1 657 ? 69.789 101.648 11.921 1.00 15.92 ? 657 HIS A C 1 ATOM 5268 O O . HIS A 1 657 ? 69.756 102.450 10.996 1.00 15.88 ? 657 HIS A O 1 ATOM 5269 C CB . HIS A 1 657 ? 67.455 101.228 12.778 1.00 16.27 ? 657 HIS A CB 1 ATOM 5270 C CG . HIS A 1 657 ? 66.159 100.533 12.507 1.00 16.81 ? 657 HIS A CG 1 ATOM 5271 N ND1 . HIS A 1 657 ? 64.948 101.189 12.544 1.00 16.64 ? 657 HIS A ND1 1 ATOM 5272 C CD2 . HIS A 1 657 ? 65.879 99.248 12.186 1.00 16.48 ? 657 HIS A CD2 1 ATOM 5273 C CE1 . HIS A 1 657 ? 63.971 100.337 12.278 1.00 16.88 ? 657 HIS A CE1 1 ATOM 5274 N NE2 . HIS A 1 657 ? 64.508 99.149 12.061 1.00 18.51 ? 657 HIS A NE2 1 ATOM 5275 N N . GLU A 1 658 ? 70.807 101.590 12.784 1.00 15.97 ? 658 GLU A N 1 ATOM 5276 C CA . GLU A 1 658 ? 71.930 102.539 12.677 1.00 17.22 ? 658 GLU A CA 1 ATOM 5277 C C . GLU A 1 658 ? 73.136 101.823 12.066 1.00 18.67 ? 658 GLU A C 1 ATOM 5278 O O . GLU A 1 658 ? 74.027 102.462 11.544 1.00 19.31 ? 658 GLU A O 1 ATOM 5279 C CB . GLU A 1 658 ? 72.317 103.071 14.049 1.00 16.32 ? 658 GLU A CB 1 ATOM 5280 C CG . GLU A 1 658 ? 71.242 104.017 14.683 1.00 18.11 ? 658 GLU A CG 1 ATOM 5281 C CD . GLU A 1 658 ? 71.083 105.307 13.877 1.00 21.40 ? 658 GLU A CD 1 ATOM 5282 O OE1 . GLU A 1 658 ? 72.126 105.955 13.526 1.00 22.21 ? 658 GLU A OE1 1 ATOM 5283 O OE2 . GLU A 1 658 ? 69.914 105.679 13.603 1.00 22.51 ? 658 GLU A OE2 1 ATOM 5284 N N . PHE A 1 659 ? 73.144 100.497 12.156 1.00 18.75 ? 659 PHE A N 1 ATOM 5285 C CA . PHE A 1 659 ? 74.327 99.725 11.782 1.00 19.52 ? 659 PHE A CA 1 ATOM 5286 C C . PHE A 1 659 ? 74.056 98.635 10.763 1.00 19.60 ? 659 PHE A C 1 ATOM 5287 O O . PHE A 1 659 ? 74.676 97.588 10.803 1.00 20.22 ? 659 PHE A O 1 ATOM 5288 C CB . PHE A 1 659 ? 75.037 99.206 13.049 1.00 18.79 ? 659 PHE A CB 1 ATOM 5289 C CG . PHE A 1 659 ? 75.430 100.305 13.989 1.00 17.56 ? 659 PHE A CG 1 ATOM 5290 C CD1 . PHE A 1 659 ? 76.477 101.156 13.675 1.00 17.04 ? 659 PHE A CD1 1 ATOM 5291 C CD2 . PHE A 1 659 ? 74.738 100.519 15.164 1.00 15.77 ? 659 PHE A CD2 1 ATOM 5292 C CE1 . PHE A 1 659 ? 76.860 102.173 14.538 1.00 13.66 ? 659 PHE A CE1 1 ATOM 5293 C CE2 . PHE A 1 659 ? 75.131 101.576 16.046 1.00 15.56 ? 659 PHE A CE2 1 ATOM 5294 C CZ . PHE A 1 659 ? 76.179 102.395 15.696 1.00 15.63 ? 659 PHE A CZ 1 ATOM 5295 N N . TYR A 1 660 ? 73.154 98.934 9.819 1.00 20.57 ? 660 TYR A N 1 ATOM 5296 C CA . TYR A 1 660 ? 72.703 97.992 8.797 1.00 20.58 ? 660 TYR A CA 1 ATOM 5297 C C . TYR A 1 660 ? 73.810 97.511 7.876 1.00 21.24 ? 660 TYR A C 1 ATOM 5298 O O . TYR A 1 660 ? 73.680 96.443 7.296 1.00 21.29 ? 660 TYR A O 1 ATOM 5299 C CB . TYR A 1 660 ? 71.526 98.593 7.996 1.00 21.38 ? 660 TYR A CB 1 ATOM 5300 C CG . TYR A 1 660 ? 71.773 100.024 7.590 1.00 19.92 ? 660 TYR A CG 1 ATOM 5301 C CD1 . TYR A 1 660 ? 72.602 100.322 6.518 1.00 20.12 ? 660 TYR A CD1 1 ATOM 5302 C CD2 . TYR A 1 660 ? 71.230 101.077 8.318 1.00 20.27 ? 660 TYR A CD2 1 ATOM 5303 C CE1 . TYR A 1 660 ? 72.871 101.638 6.153 1.00 22.07 ? 660 TYR A CE1 1 ATOM 5304 C CE2 . TYR A 1 660 ? 71.477 102.387 7.970 1.00 21.78 ? 660 TYR A CE2 1 ATOM 5305 C CZ . TYR A 1 660 ? 72.286 102.668 6.877 1.00 24.16 ? 660 TYR A CZ 1 ATOM 5306 O OH . TYR A 1 660 ? 72.549 103.993 6.537 1.00 25.86 ? 660 TYR A OH 1 ATOM 5307 N N . GLU A 1 661 ? 74.902 98.270 7.754 1.00 22.41 ? 661 GLU A N 1 ATOM 5308 C CA A GLU A 1 661 ? 76.041 97.864 6.900 0.50 22.88 ? 661 GLU A CA 1 ATOM 5309 C CA B GLU A 1 661 ? 76.037 97.862 6.908 0.50 22.53 ? 661 GLU A CA 1 ATOM 5310 C C . GLU A 1 661 ? 76.748 96.637 7.505 1.00 22.60 ? 661 GLU A C 1 ATOM 5311 O O . GLU A 1 661 ? 77.459 95.912 6.820 1.00 23.08 ? 661 GLU A O 1 ATOM 5312 C CB A GLU A 1 661 ? 77.013 99.054 6.611 0.50 22.61 ? 661 GLU A CB 1 ATOM 5313 C CB B GLU A 1 661 ? 77.007 99.044 6.615 0.50 22.46 ? 661 GLU A CB 1 ATOM 5314 C CG A GLU A 1 661 ? 76.345 100.213 5.787 0.50 22.99 ? 661 GLU A CG 1 ATOM 5315 C CG B GLU A 1 661 ? 77.465 99.892 7.813 0.50 23.64 ? 661 GLU A CG 1 ATOM 5316 C CD A GLU A 1 661 ? 77.270 101.372 5.381 0.50 24.97 ? 661 GLU A CD 1 ATOM 5317 C CD B GLU A 1 661 ? 76.467 100.990 8.287 0.50 23.05 ? 661 GLU A CD 1 ATOM 5318 O OE1 A GLU A 1 661 ? 78.511 101.233 5.463 0.50 28.76 ? 661 GLU A OE1 1 ATOM 5319 O OE1 B GLU A 1 661 ? 76.340 102.066 7.660 0.50 22.34 ? 661 GLU A OE1 1 ATOM 5320 O OE2 A GLU A 1 661 ? 76.752 102.439 4.957 0.50 26.96 ? 661 GLU A OE2 1 ATOM 5321 O OE2 B GLU A 1 661 ? 75.846 100.795 9.327 0.50 21.24 ? 661 GLU A OE2 1 ATOM 5322 N N . ASP A 1 662 ? 76.514 96.391 8.784 1.00 21.97 ? 662 ASP A N 1 ATOM 5323 C CA . ASP A 1 662 ? 77.127 95.306 9.515 1.00 21.74 ? 662 ASP A CA 1 ATOM 5324 C C . ASP A 1 662 ? 76.138 94.159 9.736 1.00 22.17 ? 662 ASP A C 1 ATOM 5325 O O . ASP A 1 662 ? 75.248 94.276 10.589 1.00 21.95 ? 662 ASP A O 1 ATOM 5326 C CB . ASP A 1 662 ? 77.521 95.838 10.895 1.00 21.87 ? 662 ASP A CB 1 ATOM 5327 C CG . ASP A 1 662 ? 78.440 94.900 11.663 1.00 21.44 ? 662 ASP A CG 1 ATOM 5328 O OD1 . ASP A 1 662 ? 78.561 93.732 11.289 1.00 18.79 ? 662 ASP A OD1 1 ATOM 5329 O OD2 . ASP A 1 662 ? 79.044 95.339 12.664 1.00 25.22 ? 662 ASP A OD2 1 ATOM 5330 N N . ASN A 1 663 ? 76.304 93.036 9.050 1.00 21.55 ? 663 ASN A N 1 ATOM 5331 C CA . ASN A 1 663 ? 75.320 91.981 9.210 1.00 22.53 ? 663 ASN A CA 1 ATOM 5332 C C . ASN A 1 663 ? 75.343 91.299 10.580 1.00 21.90 ? 663 ASN A C 1 ATOM 5333 O O . ASN A 1 663 ? 74.408 90.572 10.932 1.00 21.56 ? 663 ASN A O 1 ATOM 5334 C CB . ASN A 1 663 ? 75.328 90.975 8.033 1.00 23.66 ? 663 ASN A CB 1 ATOM 5335 C CG . ASN A 1 663 ? 76.507 90.032 8.058 1.00 27.09 ? 663 ASN A CG 1 ATOM 5336 O OD1 . ASN A 1 663 ? 77.477 90.217 8.810 1.00 33.50 ? 663 ASN A OD1 1 ATOM 5337 N ND2 . ASN A 1 663 ? 76.452 89.023 7.197 1.00 31.47 ? 663 ASN A ND2 1 ATOM 5338 N N . SER A 1 664 ? 76.362 91.571 11.386 1.00 21.47 ? 664 SER A N 1 ATOM 5339 C CA . SER A 1 664 ? 76.317 91.096 12.782 1.00 22.65 ? 664 SER A CA 1 ATOM 5340 C C . SER A 1 664 ? 75.213 91.719 13.665 1.00 22.16 ? 664 SER A C 1 ATOM 5341 O O . SER A 1 664 ? 74.896 91.167 14.724 1.00 22.29 ? 664 SER A O 1 ATOM 5342 C CB . SER A 1 664 ? 77.666 91.247 13.479 1.00 23.32 ? 664 SER A CB 1 ATOM 5343 O OG . SER A 1 664 ? 78.618 90.391 12.885 1.00 27.09 ? 664 SER A OG 1 ATOM 5344 N N . THR A 1 665 ? 74.629 92.833 13.216 1.00 21.31 ? 665 THR A N 1 ATOM 5345 C CA . THR A 1 665 ? 73.574 93.507 13.955 1.00 20.85 ? 665 THR A CA 1 ATOM 5346 C C . THR A 1 665 ? 72.185 93.062 13.521 1.00 21.74 ? 665 THR A C 1 ATOM 5347 O O . THR A 1 665 ? 71.222 93.450 14.160 1.00 23.25 ? 665 THR A O 1 ATOM 5348 C CB . THR A 1 665 ? 73.623 95.020 13.749 1.00 21.17 ? 665 THR A CB 1 ATOM 5349 O OG1 . THR A 1 665 ? 73.234 95.341 12.408 1.00 19.56 ? 665 THR A OG1 1 ATOM 5350 C CG2 . THR A 1 665 ? 75.032 95.599 14.061 1.00 16.71 ? 665 THR A CG2 1 ATOM 5351 N N . TRP A 1 666 ? 72.077 92.274 12.447 1.00 21.39 ? 666 TRP A N 1 ATOM 5352 C CA . TRP A 1 666 ? 70.756 91.995 11.828 1.00 22.24 ? 666 TRP A CA 1 ATOM 5353 C C . TRP A 1 666 ? 69.809 91.183 12.712 1.00 22.77 ? 666 TRP A C 1 ATOM 5354 O O . TRP A 1 666 ? 68.580 91.282 12.576 1.00 23.63 ? 666 TRP A O 1 ATOM 5355 C CB . TRP A 1 666 ? 70.875 91.327 10.446 1.00 21.09 ? 666 TRP A CB 1 ATOM 5356 C CG . TRP A 1 666 ? 71.523 92.200 9.361 1.00 21.30 ? 666 TRP A CG 1 ATOM 5357 C CD1 . TRP A 1 666 ? 71.876 93.517 9.455 1.00 20.57 ? 666 TRP A CD1 1 ATOM 5358 C CD2 . TRP A 1 666 ? 71.848 91.791 8.025 1.00 20.95 ? 666 TRP A CD2 1 ATOM 5359 N NE1 . TRP A 1 666 ? 72.394 93.955 8.260 1.00 19.67 ? 666 TRP A NE1 1 ATOM 5360 C CE2 . TRP A 1 666 ? 72.388 92.909 7.366 1.00 20.93 ? 666 TRP A CE2 1 ATOM 5361 C CE3 . TRP A 1 666 ? 71.728 90.580 7.321 1.00 21.46 ? 666 TRP A CE3 1 ATOM 5362 C CZ2 . TRP A 1 666 ? 72.861 92.846 6.036 1.00 20.59 ? 666 TRP A CZ2 1 ATOM 5363 C CZ3 . TRP A 1 666 ? 72.168 90.525 6.004 1.00 21.76 ? 666 TRP A CZ3 1 ATOM 5364 C CH2 . TRP A 1 666 ? 72.730 91.659 5.372 1.00 21.04 ? 666 TRP A CH2 1 ATOM 5365 N N . ASP A 1 667 ? 70.363 90.367 13.594 1.00 23.61 ? 667 ASP A N 1 ATOM 5366 C CA . ASP A 1 667 ? 69.501 89.676 14.545 1.00 25.82 ? 667 ASP A CA 1 ATOM 5367 C C . ASP A 1 667 ? 69.752 89.994 16.035 1.00 24.85 ? 667 ASP A C 1 ATOM 5368 O O . ASP A 1 667 ? 69.332 89.249 16.901 1.00 25.77 ? 667 ASP A O 1 ATOM 5369 C CB . ASP A 1 667 ? 69.493 88.173 14.249 1.00 28.03 ? 667 ASP A CB 1 ATOM 5370 C CG . ASP A 1 667 ? 70.852 87.565 14.402 1.00 32.77 ? 667 ASP A CG 1 ATOM 5371 O OD1 . ASP A 1 667 ? 71.702 88.214 15.066 1.00 37.42 ? 667 ASP A OD1 1 ATOM 5372 O OD2 . ASP A 1 667 ? 71.070 86.459 13.856 1.00 39.40 ? 667 ASP A OD2 1 ATOM 5373 N N . VAL A 1 668 ? 70.379 91.131 16.339 1.00 23.85 ? 668 VAL A N 1 ATOM 5374 C CA . VAL A 1 668 ? 70.491 91.574 17.742 1.00 22.42 ? 668 VAL A CA 1 ATOM 5375 C C . VAL A 1 668 ? 69.128 92.055 18.301 1.00 23.00 ? 668 VAL A C 1 ATOM 5376 O O . VAL A 1 668 ? 68.474 92.955 17.717 1.00 23.21 ? 668 VAL A O 1 ATOM 5377 C CB . VAL A 1 668 ? 71.569 92.647 17.915 1.00 22.73 ? 668 VAL A CB 1 ATOM 5378 C CG1 . VAL A 1 668 ? 71.591 93.161 19.368 1.00 21.62 ? 668 VAL A CG1 1 ATOM 5379 C CG2 . VAL A 1 668 ? 72.957 92.064 17.516 1.00 20.93 ? 668 VAL A CG2 1 ATOM 5380 N N . HIS A 1 669 ? 68.697 91.403 19.386 1.00 21.94 ? 669 HIS A N 1 ATOM 5381 C CA . HIS A 1 669 ? 67.473 91.726 20.112 1.00 22.60 ? 669 HIS A CA 1 ATOM 5382 C C . HIS A 1 669 ? 67.698 91.793 21.644 1.00 22.07 ? 669 HIS A C 1 ATOM 5383 O O . HIS A 1 669 ? 66.769 92.116 22.394 1.00 23.29 ? 669 HIS A O 1 ATOM 5384 C CB . HIS A 1 669 ? 66.333 90.734 19.772 1.00 23.15 ? 669 HIS A CB 1 ATOM 5385 C CG . HIS A 1 669 ? 66.678 89.302 20.034 1.00 25.27 ? 669 HIS A CG 1 ATOM 5386 N ND1 . HIS A 1 669 ? 66.419 88.681 21.236 1.00 28.12 ? 669 HIS A ND1 1 ATOM 5387 C CD2 . HIS A 1 669 ? 67.320 88.384 19.277 1.00 30.59 ? 669 HIS A CD2 1 ATOM 5388 C CE1 . HIS A 1 669 ? 66.859 87.437 21.200 1.00 28.84 ? 669 HIS A CE1 1 ATOM 5389 N NE2 . HIS A 1 669 ? 67.419 87.233 20.026 1.00 30.80 ? 669 HIS A NE2 1 ATOM 5390 N N A GLN A 1 670 ? 68.903 91.445 22.105 0.50 21.26 ? 670 GLN A N 1 ATOM 5391 N N B GLN A 1 670 ? 68.924 91.543 22.073 0.50 20.83 ? 670 GLN A N 1 ATOM 5392 C CA A GLN A 1 670 ? 69.267 91.539 23.534 0.50 21.48 ? 670 GLN A CA 1 ATOM 5393 C CA B GLN A 1 670 ? 69.273 91.553 23.481 0.50 20.43 ? 670 GLN A CA 1 ATOM 5394 C C A GLN A 1 670 ? 69.809 92.935 23.923 0.50 20.48 ? 670 GLN A C 1 ATOM 5395 C C B GLN A 1 670 ? 69.928 92.884 23.896 0.50 19.98 ? 670 GLN A C 1 ATOM 5396 O O A GLN A 1 670 ? 69.978 93.232 25.113 0.50 20.14 ? 670 GLN A O 1 ATOM 5397 O O B GLN A 1 670 ? 70.289 93.085 25.064 0.50 19.60 ? 670 GLN A O 1 ATOM 5398 C CB A GLN A 1 670 ? 70.256 90.413 23.974 0.50 21.84 ? 670 GLN A CB 1 ATOM 5399 C CB B GLN A 1 670 ? 70.163 90.345 23.800 0.50 20.96 ? 670 GLN A CB 1 ATOM 5400 C CG A GLN A 1 670 ? 69.613 89.020 24.272 0.50 21.97 ? 670 GLN A CG 1 ATOM 5401 C CG B GLN A 1 670 ? 69.737 89.058 23.085 0.50 19.98 ? 670 GLN A CG 1 ATOM 5402 C CD A GLN A 1 670 ? 70.257 88.192 25.445 0.50 23.71 ? 670 GLN A CD 1 ATOM 5403 C CD B GLN A 1 670 ? 70.540 88.793 21.807 0.50 21.96 ? 670 GLN A CD 1 ATOM 5404 O OE1 A GLN A 1 670 ? 69.756 87.105 25.777 0.50 22.56 ? 670 GLN A OE1 1 ATOM 5405 O OE1 B GLN A 1 670 ? 70.659 89.663 20.911 0.50 18.11 ? 670 GLN A OE1 1 ATOM 5406 N NE2 A GLN A 1 670 ? 71.342 88.716 26.079 0.50 25.65 ? 670 GLN A NE2 1 ATOM 5407 N NE2 B GLN A 1 670 ? 71.095 87.575 21.714 0.50 19.71 ? 670 GLN A NE2 1 ATOM 5408 N N . GLN A 1 671 ? 70.061 93.787 22.924 1.00 19.92 ? 671 GLN A N 1 ATOM 5409 C CA . GLN A 1 671 ? 70.515 95.172 23.149 1.00 19.30 ? 671 GLN A CA 1 ATOM 5410 C C . GLN A 1 671 ? 69.617 96.049 22.315 1.00 18.39 ? 671 GLN A C 1 ATOM 5411 O O . GLN A 1 671 ? 68.957 95.557 21.372 1.00 19.22 ? 671 GLN A O 1 ATOM 5412 C CB . GLN A 1 671 ? 71.962 95.387 22.668 1.00 18.92 ? 671 GLN A CB 1 ATOM 5413 C CG . GLN A 1 671 ? 73.023 94.651 23.442 1.00 18.32 ? 671 GLN A CG 1 ATOM 5414 C CD . GLN A 1 671 ? 74.328 94.526 22.646 1.00 18.97 ? 671 GLN A CD 1 ATOM 5415 O OE1 . GLN A 1 671 ? 74.454 93.648 21.818 1.00 18.87 ? 671 GLN A OE1 1 ATOM 5416 N NE2 . GLN A 1 671 ? 75.279 95.416 22.885 1.00 17.60 ? 671 GLN A NE2 1 ATOM 5417 N N . PHE A 1 672 ? 69.545 97.337 22.654 1.00 16.83 ? 672 PHE A N 1 ATOM 5418 C CA . PHE A 1 672 ? 68.852 98.313 21.783 1.00 15.64 ? 672 PHE A CA 1 ATOM 5419 C C . PHE A 1 672 ? 69.408 99.706 21.967 1.00 15.34 ? 672 PHE A C 1 ATOM 5420 O O . PHE A 1 672 ? 70.238 99.930 22.842 1.00 14.53 ? 672 PHE A O 1 ATOM 5421 C CB . PHE A 1 672 ? 67.328 98.315 21.988 1.00 15.66 ? 672 PHE A CB 1 ATOM 5422 C CG . PHE A 1 672 ? 66.868 98.780 23.356 1.00 16.04 ? 672 PHE A CG 1 ATOM 5423 C CD1 . PHE A 1 672 ? 66.262 100.030 23.513 1.00 17.00 ? 672 PHE A CD1 1 ATOM 5424 C CD2 . PHE A 1 672 ? 66.926 97.919 24.449 1.00 16.71 ? 672 PHE A CD2 1 ATOM 5425 C CE1 . PHE A 1 672 ? 65.790 100.455 24.779 1.00 14.49 ? 672 PHE A CE1 1 ATOM 5426 C CE2 . PHE A 1 672 ? 66.475 98.318 25.701 1.00 16.76 ? 672 PHE A CE2 1 ATOM 5427 C CZ . PHE A 1 672 ? 65.905 99.600 25.877 1.00 14.72 ? 672 PHE A CZ 1 ATOM 5428 N N . LEU A 1 673 ? 68.936 100.636 21.155 1.00 15.38 ? 673 LEU A N 1 ATOM 5429 C CA . LEU A 1 673 ? 69.361 102.033 21.266 1.00 16.61 ? 673 LEU A CA 1 ATOM 5430 C C . LEU A 1 673 ? 68.246 102.955 21.718 1.00 16.42 ? 673 LEU A C 1 ATOM 5431 O O . LEU A 1 673 ? 67.064 102.686 21.433 1.00 17.00 ? 673 LEU A O 1 ATOM 5432 C CB . LEU A 1 673 ? 69.827 102.512 19.873 1.00 17.16 ? 673 LEU A CB 1 ATOM 5433 C CG . LEU A 1 673 ? 70.915 101.681 19.164 1.00 15.98 ? 673 LEU A CG 1 ATOM 5434 C CD1 . LEU A 1 673 ? 70.940 102.052 17.676 1.00 15.06 ? 673 LEU A CD1 1 ATOM 5435 C CD2 . LEU A 1 673 ? 72.255 101.938 19.792 1.00 17.58 ? 673 LEU A CD2 1 ATOM 5436 N N . TRP A 1 674 ? 68.603 104.063 22.379 1.00 15.92 ? 674 TRP A N 1 ATOM 5437 C CA . TRP A 1 674 ? 67.734 105.244 22.392 1.00 15.85 ? 674 TRP A CA 1 ATOM 5438 C C . TRP A 1 674 ? 68.197 106.130 21.256 1.00 16.54 ? 674 TRP A C 1 ATOM 5439 O O . TRP A 1 674 ? 69.322 106.708 21.320 1.00 16.77 ? 674 TRP A O 1 ATOM 5440 C CB . TRP A 1 674 ? 67.870 106.051 23.675 1.00 16.41 ? 674 TRP A CB 1 ATOM 5441 C CG . TRP A 1 674 ? 67.037 105.635 24.827 1.00 17.90 ? 674 TRP A CG 1 ATOM 5442 C CD1 . TRP A 1 674 ? 66.352 104.462 24.983 1.00 19.43 ? 674 TRP A CD1 1 ATOM 5443 C CD2 . TRP A 1 674 ? 66.829 106.385 26.030 1.00 18.71 ? 674 TRP A CD2 1 ATOM 5444 N NE1 . TRP A 1 674 ? 65.720 104.441 26.204 1.00 19.66 ? 674 TRP A NE1 1 ATOM 5445 C CE2 . TRP A 1 674 ? 65.977 105.616 26.861 1.00 18.95 ? 674 TRP A CE2 1 ATOM 5446 C CE3 . TRP A 1 674 ? 67.270 107.638 26.479 1.00 17.40 ? 674 TRP A CE3 1 ATOM 5447 C CZ2 . TRP A 1 674 ? 65.563 106.052 28.131 1.00 19.79 ? 674 TRP A CZ2 1 ATOM 5448 C CZ3 . TRP A 1 674 ? 66.860 108.079 27.735 1.00 18.60 ? 674 TRP A CZ3 1 ATOM 5449 C CH2 . TRP A 1 674 ? 66.003 107.282 28.550 1.00 18.97 ? 674 TRP A CH2 1 ATOM 5450 N N . GLY A 1 675 ? 67.368 106.255 20.226 1.00 15.20 ? 675 GLY A N 1 ATOM 5451 C CA . GLY A 1 675 ? 67.719 107.032 19.058 1.00 15.52 ? 675 GLY A CA 1 ATOM 5452 C C . GLY A 1 675 ? 69.029 106.539 18.436 1.00 17.45 ? 675 GLY A C 1 ATOM 5453 O O . GLY A 1 675 ? 69.305 105.331 18.407 1.00 14.83 ? 675 GLY A O 1 ATOM 5454 N N . PRO A 1 676 ? 69.828 107.482 17.885 1.00 18.34 ? 676 PRO A N 1 ATOM 5455 C CA . PRO A 1 676 ? 71.088 107.081 17.239 1.00 19.06 ? 676 PRO A CA 1 ATOM 5456 C C . PRO A 1 676 ? 72.262 106.825 18.193 1.00 19.66 ? 676 PRO A C 1 ATOM 5457 O O . PRO A 1 676 ? 73.213 106.140 17.809 1.00 20.04 ? 676 PRO A O 1 ATOM 5458 C CB . PRO A 1 676 ? 71.370 108.262 16.322 1.00 19.60 ? 676 PRO A CB 1 ATOM 5459 C CG . PRO A 1 676 ? 70.867 109.459 17.186 1.00 19.36 ? 676 PRO A CG 1 ATOM 5460 C CD . PRO A 1 676 ? 69.560 108.925 17.741 1.00 18.54 ? 676 PRO A CD 1 ATOM 5461 N N . GLY A 1 677 ? 72.188 107.303 19.434 1.00 19.54 ? 677 GLY A N 1 ATOM 5462 C CA . GLY A 1 677 ? 73.413 107.536 20.185 1.00 19.86 ? 677 GLY A CA 1 ATOM 5463 C C . GLY A 1 677 ? 73.665 106.796 21.481 1.00 19.79 ? 677 GLY A C 1 ATOM 5464 O O . GLY A 1 677 ? 74.802 106.752 21.919 1.00 19.27 ? 677 GLY A O 1 ATOM 5465 N N . LEU A 1 678 ? 72.618 106.261 22.117 1.00 18.03 ? 678 LEU A N 1 ATOM 5466 C CA . LEU A 1 678 ? 72.758 105.553 23.381 1.00 18.53 ? 678 LEU A CA 1 ATOM 5467 C C . LEU A 1 678 ? 72.477 104.049 23.247 1.00 18.95 ? 678 LEU A C 1 ATOM 5468 O O . LEU A 1 678 ? 71.339 103.633 22.905 1.00 19.82 ? 678 LEU A O 1 ATOM 5469 C CB . LEU A 1 678 ? 71.828 106.154 24.476 1.00 18.64 ? 678 LEU A CB 1 ATOM 5470 C CG . LEU A 1 678 ? 71.677 105.389 25.800 1.00 18.04 ? 678 LEU A CG 1 ATOM 5471 C CD1 . LEU A 1 678 ? 72.976 105.434 26.600 1.00 20.21 ? 678 LEU A CD1 1 ATOM 5472 C CD2 . LEU A 1 678 ? 70.540 105.999 26.656 1.00 18.05 ? 678 LEU A CD2 1 ATOM 5473 N N . LEU A 1 679 ? 73.495 103.256 23.591 1.00 18.44 ? 679 LEU A N 1 ATOM 5474 C CA . LEU A 1 679 ? 73.475 101.817 23.515 1.00 18.26 ? 679 LEU A CA 1 ATOM 5475 C C . LEU A 1 679 ? 73.217 101.203 24.881 1.00 18.55 ? 679 LEU A C 1 ATOM 5476 O O . LEU A 1 679 ? 74.001 101.385 25.820 1.00 17.67 ? 679 LEU A O 1 ATOM 5477 C CB . LEU A 1 679 ? 74.817 101.318 22.941 1.00 19.02 ? 679 LEU A CB 1 ATOM 5478 C CG . LEU A 1 679 ? 75.050 99.794 22.895 1.00 18.99 ? 679 LEU A CG 1 ATOM 5479 C CD1 . LEU A 1 679 ? 74.022 99.094 22.006 1.00 17.99 ? 679 LEU A CD1 1 ATOM 5480 C CD2 . LEU A 1 679 ? 76.474 99.457 22.454 1.00 18.76 ? 679 LEU A CD2 1 ATOM 5481 N N . ILE A 1 680 ? 72.131 100.432 24.982 1.00 17.86 ? 680 ILE A N 1 ATOM 5482 C CA . ILE A 1 680 ? 71.749 99.810 26.238 1.00 17.17 ? 680 ILE A CA 1 ATOM 5483 C C . ILE A 1 680 ? 72.003 98.308 26.201 1.00 18.30 ? 680 ILE A C 1 ATOM 5484 O O . ILE A 1 680 ? 71.484 97.619 25.322 1.00 18.07 ? 680 ILE A O 1 ATOM 5485 C CB . ILE A 1 680 ? 70.272 100.118 26.553 1.00 16.01 ? 680 ILE A CB 1 ATOM 5486 C CG1 . ILE A 1 680 ? 70.116 101.632 26.698 1.00 17.77 ? 680 ILE A CG1 1 ATOM 5487 C CG2 . ILE A 1 680 ? 69.842 99.445 27.859 1.00 16.47 ? 680 ILE A CG2 1 ATOM 5488 C CD1 . ILE A 1 680 ? 68.964 102.195 26.028 1.00 19.55 ? 680 ILE A CD1 1 ATOM 5489 N N . THR A 1 681 ? 72.791 97.802 27.161 1.00 18.73 ? 681 THR A N 1 ATOM 5490 C CA . THR A 1 681 ? 73.185 96.395 27.187 1.00 18.57 ? 681 THR A CA 1 ATOM 5491 C C . THR A 1 681 ? 72.875 95.813 28.563 1.00 19.02 ? 681 THR A C 1 ATOM 5492 O O . THR A 1 681 ? 73.671 95.946 29.500 1.00 19.30 ? 681 THR A O 1 ATOM 5493 C CB . THR A 1 681 ? 74.702 96.206 26.905 1.00 19.80 ? 681 THR A CB 1 ATOM 5494 O OG1 . THR A 1 681 ? 75.080 96.960 25.739 1.00 21.28 ? 681 THR A OG1 1 ATOM 5495 C CG2 . THR A 1 681 ? 75.025 94.739 26.696 1.00 17.57 ? 681 THR A CG2 1 ATOM 5496 N N . PRO A 1 682 ? 71.687 95.201 28.707 1.00 18.63 ? 682 PRO A N 1 ATOM 5497 C CA . PRO A 1 682 ? 71.305 94.575 29.960 1.00 18.08 ? 682 PRO A CA 1 ATOM 5498 C C . PRO A 1 682 ? 71.843 93.165 30.142 1.00 18.59 ? 682 PRO A C 1 ATOM 5499 O O . PRO A 1 682 ? 72.059 92.430 29.156 1.00 18.29 ? 682 PRO A O 1 ATOM 5500 C CB . PRO A 1 682 ? 69.780 94.517 29.852 1.00 17.68 ? 682 PRO A CB 1 ATOM 5501 C CG . PRO A 1 682 ? 69.554 94.266 28.388 1.00 17.25 ? 682 PRO A CG 1 ATOM 5502 C CD . PRO A 1 682 ? 70.586 95.177 27.721 1.00 17.91 ? 682 PRO A CD 1 ATOM 5503 N N . VAL A 1 683 ? 72.042 92.792 31.410 1.00 19.23 ? 683 VAL A N 1 ATOM 5504 C CA . VAL A 1 683 ? 72.249 91.401 31.780 1.00 20.43 ? 683 VAL A CA 1 ATOM 5505 C C . VAL A 1 683 ? 70.845 90.783 31.810 1.00 21.43 ? 683 VAL A C 1 ATOM 5506 O O . VAL A 1 683 ? 69.965 91.317 32.461 1.00 21.72 ? 683 VAL A O 1 ATOM 5507 C CB . VAL A 1 683 ? 72.958 91.283 33.160 1.00 19.62 ? 683 VAL A CB 1 ATOM 5508 C CG1 . VAL A 1 683 ? 72.899 89.858 33.687 1.00 19.74 ? 683 VAL A CG1 1 ATOM 5509 C CG2 . VAL A 1 683 ? 74.425 91.797 33.046 1.00 19.89 ? 683 VAL A CG2 1 ATOM 5510 N N . LEU A 1 684 ? 70.643 89.696 31.076 1.00 22.47 ? 684 LEU A N 1 ATOM 5511 C CA . LEU A 1 684 ? 69.322 89.114 30.934 1.00 23.90 ? 684 LEU A CA 1 ATOM 5512 C C . LEU A 1 684 ? 69.292 87.644 31.362 1.00 25.11 ? 684 LEU A C 1 ATOM 5513 O O . LEU A 1 684 ? 68.299 86.968 31.127 1.00 25.09 ? 684 LEU A O 1 ATOM 5514 C CB . LEU A 1 684 ? 68.808 89.257 29.478 1.00 23.14 ? 684 LEU A CB 1 ATOM 5515 C CG . LEU A 1 684 ? 68.620 90.657 28.882 1.00 21.67 ? 684 LEU A CG 1 ATOM 5516 C CD1 . LEU A 1 684 ? 68.503 90.611 27.349 1.00 18.78 ? 684 LEU A CD1 1 ATOM 5517 C CD2 . LEU A 1 684 ? 67.442 91.447 29.521 1.00 18.23 ? 684 LEU A CD2 1 ATOM 5518 N N . ASP A 1 685 ? 70.370 87.154 31.972 1.00 27.05 ? 685 ASP A N 1 ATOM 5519 C CA . ASP A 1 685 ? 70.432 85.740 32.401 1.00 29.65 ? 685 ASP A CA 1 ATOM 5520 C C . ASP A 1 685 ? 70.636 85.617 33.895 1.00 29.33 ? 685 ASP A C 1 ATOM 5521 O O . ASP A 1 685 ? 71.446 86.326 34.466 1.00 29.57 ? 685 ASP A O 1 ATOM 5522 C CB . ASP A 1 685 ? 71.557 84.957 31.709 1.00 30.08 ? 685 ASP A CB 1 ATOM 5523 C CG . ASP A 1 685 ? 71.524 85.068 30.203 1.00 35.45 ? 685 ASP A CG 1 ATOM 5524 O OD1 . ASP A 1 685 ? 70.617 84.499 29.541 1.00 37.53 ? 685 ASP A OD1 1 ATOM 5525 O OD2 . ASP A 1 685 ? 72.455 85.724 29.675 1.00 42.31 ? 685 ASP A OD2 1 ATOM 5526 N N . GLU A 1 686 ? 69.898 84.707 34.515 1.00 29.71 ? 686 GLU A N 1 ATOM 5527 C CA . GLU A 1 686 ? 70.019 84.456 35.945 1.00 30.70 ? 686 GLU A CA 1 ATOM 5528 C C . GLU A 1 686 ? 71.465 84.103 36.368 1.00 30.97 ? 686 GLU A C 1 ATOM 5529 O O . GLU A 1 686 ? 72.172 83.343 35.687 1.00 30.22 ? 686 GLU A O 1 ATOM 5530 C CB . GLU A 1 686 ? 69.064 83.328 36.309 1.00 31.54 ? 686 GLU A CB 1 ATOM 5531 C CG . GLU A 1 686 ? 68.882 83.062 37.784 1.00 32.78 ? 686 GLU A CG 1 ATOM 5532 C CD . GLU A 1 686 ? 67.802 82.028 38.030 1.00 35.08 ? 686 GLU A CD 1 ATOM 5533 O OE1 . GLU A 1 686 ? 67.265 81.454 37.065 1.00 37.49 ? 686 GLU A OE1 1 ATOM 5534 O OE2 . GLU A 1 686 ? 67.483 81.779 39.194 1.00 39.69 ? 686 GLU A OE2 1 ATOM 5535 N N . GLY A 1 687 ? 71.919 84.726 37.448 1.00 31.06 ? 687 GLY A N 1 ATOM 5536 C CA . GLY A 1 687 ? 73.233 84.435 37.992 1.00 32.22 ? 687 GLY A CA 1 ATOM 5537 C C . GLY A 1 687 ? 74.387 85.055 37.236 1.00 32.77 ? 687 GLY A C 1 ATOM 5538 O O . GLY A 1 687 ? 75.545 84.924 37.668 1.00 33.67 ? 687 GLY A O 1 ATOM 5539 N N . ALA A 1 688 ? 74.105 85.727 36.120 1.00 32.67 ? 688 ALA A N 1 ATOM 5540 C CA . ALA A 1 688 ? 75.187 86.343 35.324 1.00 33.21 ? 688 ALA A CA 1 ATOM 5541 C C . ALA A 1 688 ? 75.659 87.711 35.856 1.00 33.38 ? 688 ALA A C 1 ATOM 5542 O O . ALA A 1 688 ? 74.866 88.509 36.381 1.00 32.14 ? 688 ALA A O 1 ATOM 5543 C CB . ALA A 1 688 ? 74.802 86.423 33.826 1.00 33.33 ? 688 ALA A CB 1 ATOM 5544 N N . GLU A 1 689 ? 76.957 87.955 35.717 1.00 34.21 ? 689 GLU A N 1 ATOM 5545 C CA . GLU A 1 689 ? 77.584 89.247 36.031 1.00 36.65 ? 689 GLU A CA 1 ATOM 5546 C C . GLU A 1 689 ? 78.359 89.738 34.795 1.00 35.69 ? 689 GLU A C 1 ATOM 5547 O O . GLU A 1 689 ? 79.270 90.562 34.873 1.00 34.79 ? 689 GLU A O 1 ATOM 5548 C CB . GLU A 1 689 ? 78.491 89.124 37.269 1.00 36.49 ? 689 GLU A CB 1 ATOM 5549 C CG . GLU A 1 689 ? 77.719 88.803 38.565 1.00 39.50 ? 689 GLU A CG 1 ATOM 5550 C CD . GLU A 1 689 ? 78.624 88.708 39.781 1.00 41.63 ? 689 GLU A CD 1 ATOM 5551 O OE1 . GLU A 1 689 ? 78.959 87.561 40.202 1.00 48.89 ? 689 GLU A OE1 1 ATOM 5552 O OE2 . GLU A 1 689 ? 79.027 89.782 40.305 1.00 48.75 ? 689 GLU A OE2 1 ATOM 5553 N N . LYS A 1 690 ? 77.965 89.194 33.651 1.00 36.06 ? 690 LYS A N 1 ATOM 5554 C CA . LYS A 1 690 ? 78.574 89.479 32.360 1.00 37.01 ? 690 LYS A CA 1 ATOM 5555 C C . LYS A 1 690 ? 77.484 89.304 31.335 1.00 36.34 ? 690 LYS A C 1 ATOM 5556 O O . LYS A 1 690 ? 76.544 88.537 31.523 1.00 36.10 ? 690 LYS A O 1 ATOM 5557 C CB . LYS A 1 690 ? 79.632 88.431 31.967 1.00 37.31 ? 690 LYS A CB 1 ATOM 5558 C CG . LYS A 1 690 ? 80.768 88.180 32.907 1.00 41.90 ? 690 LYS A CG 1 ATOM 5559 C CD . LYS A 1 690 ? 81.493 86.915 32.450 1.00 46.92 ? 690 LYS A CD 1 ATOM 5560 C CE . LYS A 1 690 ? 82.575 86.487 33.449 1.00 49.81 ? 690 LYS A CE 1 ATOM 5561 N NZ . LYS A 1 690 ? 83.439 85.393 32.850 1.00 51.02 ? 690 LYS A NZ 1 ATOM 5562 N N . VAL A 1 691 ? 77.656 89.979 30.212 1.00 36.12 ? 691 VAL A N 1 ATOM 5563 C CA . VAL A 1 691 ? 76.808 89.734 29.072 1.00 35.76 ? 691 VAL A CA 1 ATOM 5564 C C . VAL A 1 691 ? 77.653 89.695 27.782 1.00 35.05 ? 691 VAL A C 1 ATOM 5565 O O . VAL A 1 691 ? 78.505 90.583 27.556 1.00 35.00 ? 691 VAL A O 1 ATOM 5566 C CB . VAL A 1 691 ? 75.699 90.795 29.027 1.00 35.36 ? 691 VAL A CB 1 ATOM 5567 C CG1 . VAL A 1 691 ? 76.218 92.121 28.512 1.00 36.28 ? 691 VAL A CG1 1 ATOM 5568 C CG2 . VAL A 1 691 ? 74.536 90.318 28.191 1.00 38.40 ? 691 VAL A CG2 1 ATOM 5569 N N . MET A 1 692 ? 77.454 88.647 26.976 1.00 34.87 ? 692 MET A N 1 ATOM 5570 C CA . MET A 1 692 ? 77.969 88.611 25.595 1.00 34.44 ? 692 MET A CA 1 ATOM 5571 C C . MET A 1 692 ? 77.131 89.639 24.848 1.00 32.77 ? 692 MET A C 1 ATOM 5572 O O . MET A 1 692 ? 75.886 89.580 24.883 1.00 32.18 ? 692 MET A O 1 ATOM 5573 C CB . MET A 1 692 ? 77.827 87.215 24.951 1.00 36.59 ? 692 MET A CB 1 ATOM 5574 C CG . MET A 1 692 ? 78.794 86.134 25.505 1.00 40.15 ? 692 MET A CG 1 ATOM 5575 S SD . MET A 1 692 ? 80.534 86.516 25.146 1.00 51.75 ? 692 MET A SD 1 ATOM 5576 C CE . MET A 1 692 ? 81.412 85.192 26.013 1.00 47.01 ? 692 MET A CE 1 ATOM 5577 N N . ALA A 1 693 ? 77.804 90.608 24.240 1.00 29.78 ? 693 ALA A N 1 ATOM 5578 C CA . ALA A 1 693 ? 77.139 91.772 23.661 1.00 28.20 ? 693 ALA A CA 1 ATOM 5579 C C . ALA A 1 693 ? 77.831 92.178 22.364 1.00 27.16 ? 693 ALA A C 1 ATOM 5580 O O . ALA A 1 693 ? 79.025 91.968 22.217 1.00 26.22 ? 693 ALA A O 1 ATOM 5581 C CB . ALA A 1 693 ? 77.197 92.931 24.642 1.00 28.11 ? 693 ALA A CB 1 ATOM 5582 N N . TYR A 1 694 ? 77.092 92.798 21.444 1.00 25.94 ? 694 TYR A N 1 ATOM 5583 C CA . TYR A 1 694 ? 77.711 93.340 20.233 1.00 24.09 ? 694 TYR A CA 1 ATOM 5584 C C . TYR A 1 694 ? 78.080 94.821 20.383 1.00 23.58 ? 694 TYR A C 1 ATOM 5585 O O . TYR A 1 694 ? 77.310 95.636 20.912 1.00 24.13 ? 694 TYR A O 1 ATOM 5586 C CB . TYR A 1 694 ? 76.897 93.022 18.958 1.00 24.40 ? 694 TYR A CB 1 ATOM 5587 C CG . TYR A 1 694 ? 77.703 93.229 17.697 1.00 24.03 ? 694 TYR A CG 1 ATOM 5588 C CD1 . TYR A 1 694 ? 78.736 92.347 17.364 1.00 25.42 ? 694 TYR A CD1 1 ATOM 5589 C CD2 . TYR A 1 694 ? 77.477 94.322 16.865 1.00 20.99 ? 694 TYR A CD2 1 ATOM 5590 C CE1 . TYR A 1 694 ? 79.520 92.548 16.233 1.00 25.53 ? 694 TYR A CE1 1 ATOM 5591 C CE2 . TYR A 1 694 ? 78.268 94.529 15.718 1.00 23.17 ? 694 TYR A CE2 1 ATOM 5592 C CZ . TYR A 1 694 ? 79.278 93.620 15.416 1.00 23.75 ? 694 TYR A CZ 1 ATOM 5593 O OH . TYR A 1 694 ? 80.077 93.797 14.315 1.00 25.46 ? 694 TYR A OH 1 ATOM 5594 N N . VAL A 1 695 ? 79.295 95.158 19.986 1.00 21.63 ? 695 VAL A N 1 ATOM 5595 C CA . VAL A 1 695 ? 79.729 96.540 19.942 1.00 20.67 ? 695 VAL A CA 1 ATOM 5596 C C . VAL A 1 695 ? 79.799 96.918 18.465 1.00 21.23 ? 695 VAL A C 1 ATOM 5597 O O . VAL A 1 695 ? 80.685 96.434 17.744 1.00 20.84 ? 695 VAL A O 1 ATOM 5598 C CB . VAL A 1 695 ? 81.102 96.702 20.608 1.00 21.27 ? 695 VAL A CB 1 ATOM 5599 C CG1 . VAL A 1 695 ? 81.614 98.137 20.516 1.00 19.11 ? 695 VAL A CG1 1 ATOM 5600 C CG2 . VAL A 1 695 ? 81.013 96.242 22.050 1.00 18.83 ? 695 VAL A CG2 1 ATOM 5601 N N . PRO A 1 696 ? 78.819 97.716 17.986 1.00 20.56 ? 696 PRO A N 1 ATOM 5602 C CA . PRO A 1 696 ? 78.816 98.143 16.593 1.00 20.76 ? 696 PRO A CA 1 ATOM 5603 C C . PRO A 1 696 ? 80.045 98.968 16.173 1.00 21.54 ? 696 PRO A C 1 ATOM 5604 O O . PRO A 1 696 ? 80.884 99.378 17.011 1.00 21.30 ? 696 PRO A O 1 ATOM 5605 C CB . PRO A 1 696 ? 77.550 98.989 16.488 1.00 20.79 ? 696 PRO A CB 1 ATOM 5606 C CG . PRO A 1 696 ? 76.680 98.517 17.569 1.00 21.46 ? 696 PRO A CG 1 ATOM 5607 C CD . PRO A 1 696 ? 77.645 98.223 18.706 1.00 20.82 ? 696 PRO A CD 1 ATOM 5608 N N . ASP A 1 697 ? 80.133 99.178 14.873 1.00 21.25 ? 697 ASP A N 1 ATOM 5609 C CA . ASP A 1 697 ? 81.258 99.841 14.224 1.00 22.30 ? 697 ASP A CA 1 ATOM 5610 C C . ASP A 1 697 ? 81.203 101.360 14.408 1.00 21.79 ? 697 ASP A C 1 ATOM 5611 O O . ASP A 1 697 ? 80.782 102.103 13.528 1.00 22.37 ? 697 ASP A O 1 ATOM 5612 C CB . ASP A 1 697 ? 81.287 99.463 12.727 1.00 22.28 ? 697 ASP A CB 1 ATOM 5613 C CG . ASP A 1 697 ? 82.573 99.903 12.034 1.00 24.85 ? 697 ASP A CG 1 ATOM 5614 O OD1 . ASP A 1 697 ? 83.522 100.296 12.729 1.00 26.00 ? 697 ASP A OD1 1 ATOM 5615 O OD2 . ASP A 1 697 ? 82.618 99.848 10.787 1.00 25.44 ? 697 ASP A OD2 1 ATOM 5616 N N . ALA A 1 698 ? 81.636 101.807 15.578 1.00 21.52 ? 698 ALA A N 1 ATOM 5617 C CA . ALA A 1 698 ? 81.608 103.229 15.933 1.00 21.04 ? 698 ALA A CA 1 ATOM 5618 C C . ALA A 1 698 ? 82.518 103.417 17.120 1.00 20.35 ? 698 ALA A C 1 ATOM 5619 O O . ALA A 1 698 ? 82.924 102.442 17.754 1.00 21.08 ? 698 ALA A O 1 ATOM 5620 C CB . ALA A 1 698 ? 80.177 103.662 16.301 1.00 20.35 ? 698 ALA A CB 1 ATOM 5621 N N . VAL A 1 699 ? 82.836 104.667 17.428 1.00 21.15 ? 699 VAL A N 1 ATOM 5622 C CA . VAL A 1 699 ? 83.453 105.012 18.713 1.00 21.22 ? 699 VAL A CA 1 ATOM 5623 C C . VAL A 1 699 ? 82.385 104.929 19.825 1.00 21.39 ? 699 VAL A C 1 ATOM 5624 O O . VAL A 1 699 ? 81.268 105.449 19.651 1.00 22.12 ? 699 VAL A O 1 ATOM 5625 C CB . VAL A 1 699 ? 84.114 106.427 18.667 1.00 21.54 ? 699 VAL A CB 1 ATOM 5626 C CG1 . VAL A 1 699 ? 84.674 106.796 20.043 1.00 19.68 ? 699 VAL A CG1 1 ATOM 5627 C CG2 . VAL A 1 699 ? 85.227 106.468 17.602 1.00 21.67 ? 699 VAL A CG2 1 ATOM 5628 N N . TRP A 1 700 ? 82.713 104.266 20.936 1.00 20.59 ? 700 TRP A N 1 ATOM 5629 C CA . TRP A 1 700 ? 81.805 104.147 22.079 1.00 20.67 ? 700 TRP A CA 1 ATOM 5630 C C . TRP A 1 700 ? 82.514 104.594 23.364 1.00 21.56 ? 700 TRP A C 1 ATOM 5631 O O . TRP A 1 700 ? 83.723 104.349 23.520 1.00 21.11 ? 700 TRP A O 1 ATOM 5632 C CB . TRP A 1 700 ? 81.298 102.711 22.238 1.00 20.17 ? 700 TRP A CB 1 ATOM 5633 C CG . TRP A 1 700 ? 80.416 102.242 21.055 1.00 20.32 ? 700 TRP A CG 1 ATOM 5634 C CD1 . TRP A 1 700 ? 80.793 101.407 20.027 1.00 19.89 ? 700 TRP A CD1 1 ATOM 5635 C CD2 . TRP A 1 700 ? 79.044 102.604 20.788 1.00 19.58 ? 700 TRP A CD2 1 ATOM 5636 N NE1 . TRP A 1 700 ? 79.751 101.219 19.154 1.00 19.60 ? 700 TRP A NE1 1 ATOM 5637 C CE2 . TRP A 1 700 ? 78.661 101.932 19.598 1.00 20.20 ? 700 TRP A CE2 1 ATOM 5638 C CE3 . TRP A 1 700 ? 78.093 103.400 21.455 1.00 18.21 ? 700 TRP A CE3 1 ATOM 5639 C CZ2 . TRP A 1 700 ? 77.373 102.059 19.044 1.00 22.24 ? 700 TRP A CZ2 1 ATOM 5640 C CZ3 . TRP A 1 700 ? 76.817 103.520 20.914 1.00 18.82 ? 700 TRP A CZ3 1 ATOM 5641 C CH2 . TRP A 1 700 ? 76.465 102.857 19.713 1.00 19.66 ? 700 TRP A CH2 1 ATOM 5642 N N . TYR A 1 701 ? 81.767 105.294 24.236 1.00 20.76 ? 701 TYR A N 1 ATOM 5643 C CA . TYR A 1 701 ? 82.250 105.758 25.543 1.00 20.80 ? 701 TYR A CA 1 ATOM 5644 C C . TYR A 1 701 ? 81.356 105.209 26.624 1.00 21.14 ? 701 TYR A C 1 ATOM 5645 O O . TYR A 1 701 ? 80.130 105.250 26.516 1.00 21.34 ? 701 TYR A O 1 ATOM 5646 C CB . TYR A 1 701 ? 82.257 107.280 25.612 1.00 20.04 ? 701 TYR A CB 1 ATOM 5647 C CG . TYR A 1 701 ? 83.116 107.963 24.546 1.00 21.27 ? 701 TYR A CG 1 ATOM 5648 C CD1 . TYR A 1 701 ? 84.485 108.188 24.749 1.00 21.24 ? 701 TYR A CD1 1 ATOM 5649 C CD2 . TYR A 1 701 ? 82.555 108.397 23.349 1.00 23.73 ? 701 TYR A CD2 1 ATOM 5650 C CE1 . TYR A 1 701 ? 85.271 108.819 23.776 1.00 20.39 ? 701 TYR A CE1 1 ATOM 5651 C CE2 . TYR A 1 701 ? 83.323 109.022 22.386 1.00 22.35 ? 701 TYR A CE2 1 ATOM 5652 C CZ . TYR A 1 701 ? 84.684 109.238 22.614 1.00 21.12 ? 701 TYR A CZ 1 ATOM 5653 O OH . TYR A 1 701 ? 85.438 109.860 21.644 1.00 20.21 ? 701 TYR A OH 1 ATOM 5654 N N . ASP A 1 702 ? 81.950 104.676 27.668 1.00 21.22 ? 702 ASP A N 1 ATOM 5655 C CA . ASP A 1 702 ? 81.182 104.306 28.839 1.00 22.68 ? 702 ASP A CA 1 ATOM 5656 C C . ASP A 1 702 ? 80.458 105.532 29.448 1.00 23.06 ? 702 ASP A C 1 ATOM 5657 O O . ASP A 1 702 ? 81.079 106.554 29.754 1.00 22.06 ? 702 ASP A O 1 ATOM 5658 C CB . ASP A 1 702 ? 82.108 103.691 29.858 1.00 22.20 ? 702 ASP A CB 1 ATOM 5659 C CG . ASP A 1 702 ? 81.372 103.127 31.006 1.00 27.25 ? 702 ASP A CG 1 ATOM 5660 O OD1 . ASP A 1 702 ? 80.746 102.059 30.830 1.00 31.57 ? 702 ASP A OD1 1 ATOM 5661 O OD2 . ASP A 1 702 ? 81.391 103.763 32.079 1.00 30.81 ? 702 ASP A OD2 1 ATOM 5662 N N . TYR A 1 703 ? 79.143 105.432 29.624 1.00 24.01 ? 703 TYR A N 1 ATOM 5663 C CA . TYR A 1 703 ? 78.358 106.565 30.147 1.00 24.07 ? 703 TYR A CA 1 ATOM 5664 C C . TYR A 1 703 ? 78.855 107.000 31.496 1.00 25.04 ? 703 TYR A C 1 ATOM 5665 O O . TYR A 1 703 ? 78.976 108.181 31.745 1.00 25.53 ? 703 TYR A O 1 ATOM 5666 C CB . TYR A 1 703 ? 76.850 106.252 30.264 1.00 23.83 ? 703 TYR A CB 1 ATOM 5667 C CG . TYR A 1 703 ? 76.058 107.388 30.868 1.00 23.02 ? 703 TYR A CG 1 ATOM 5668 C CD1 . TYR A 1 703 ? 75.552 108.409 30.073 1.00 24.75 ? 703 TYR A CD1 1 ATOM 5669 C CD2 . TYR A 1 703 ? 75.859 107.470 32.247 1.00 24.96 ? 703 TYR A CD2 1 ATOM 5670 C CE1 . TYR A 1 703 ? 74.830 109.496 30.636 1.00 24.52 ? 703 TYR A CE1 1 ATOM 5671 C CE2 . TYR A 1 703 ? 75.144 108.551 32.825 1.00 25.46 ? 703 TYR A CE2 1 ATOM 5672 C CZ . TYR A 1 703 ? 74.643 109.556 32.005 1.00 26.36 ? 703 TYR A CZ 1 ATOM 5673 O OH . TYR A 1 703 ? 73.930 110.602 32.559 1.00 26.62 ? 703 TYR A OH 1 ATOM 5674 N N . GLU A 1 704 ? 79.092 106.045 32.382 1.00 26.40 ? 704 GLU A N 1 ATOM 5675 C CA . GLU A 1 704 ? 79.386 106.353 33.776 1.00 28.70 ? 704 GLU A CA 1 ATOM 5676 C C . GLU A 1 704 ? 80.802 106.916 33.983 1.00 28.27 ? 704 GLU A C 1 ATOM 5677 O O . GLU A 1 704 ? 80.957 107.932 34.638 1.00 28.02 ? 704 GLU A O 1 ATOM 5678 C CB . GLU A 1 704 ? 79.018 105.150 34.676 1.00 28.35 ? 704 GLU A CB 1 ATOM 5679 C CG . GLU A 1 704 ? 77.489 104.778 34.450 1.00 31.60 ? 704 GLU A CG 1 ATOM 5680 C CD . GLU A 1 704 ? 76.843 103.823 35.471 1.00 32.72 ? 704 GLU A CD 1 ATOM 5681 O OE1 . GLU A 1 704 ? 77.021 104.016 36.675 1.00 37.28 ? 704 GLU A OE1 1 ATOM 5682 O OE2 . GLU A 1 704 ? 76.099 102.885 35.051 1.00 39.56 ? 704 GLU A OE2 1 ATOM 5683 N N . THR A 1 705 ? 81.823 106.299 33.396 1.00 28.25 ? 705 THR A N 1 ATOM 5684 C CA . THR A 1 705 ? 83.181 106.846 33.526 1.00 28.86 ? 705 THR A CA 1 ATOM 5685 C C . THR A 1 705 ? 83.589 107.832 32.414 1.00 28.77 ? 705 THR A C 1 ATOM 5686 O O . THR A 1 705 ? 84.483 108.660 32.608 1.00 29.00 ? 705 THR A O 1 ATOM 5687 C CB . THR A 1 705 ? 84.220 105.736 33.591 1.00 28.79 ? 705 THR A CB 1 ATOM 5688 O OG1 . THR A 1 705 ? 84.175 105.016 32.367 1.00 29.61 ? 705 THR A OG1 1 ATOM 5689 C CG2 . THR A 1 705 ? 83.905 104.772 34.751 1.00 29.94 ? 705 THR A CG2 1 ATOM 5690 N N . GLY A 1 706 ? 82.945 107.740 31.251 1.00 28.27 ? 706 GLY A N 1 ATOM 5691 C CA . GLY A 1 706 ? 83.283 108.597 30.118 1.00 27.50 ? 706 GLY A CA 1 ATOM 5692 C C . GLY A 1 706 ? 84.407 107.994 29.281 1.00 27.95 ? 706 GLY A C 1 ATOM 5693 O O . GLY A 1 706 ? 84.781 108.521 28.235 1.00 27.15 ? 706 GLY A O 1 ATOM 5694 N N . SER A 1 707 ? 84.933 106.873 29.746 1.00 27.92 ? 707 SER A N 1 ATOM 5695 C CA . SER A 1 707 ? 86.057 106.208 29.115 1.00 29.22 ? 707 SER A CA 1 ATOM 5696 C C . SER A 1 707 ? 85.724 105.575 27.736 1.00 29.33 ? 707 SER A C 1 ATOM 5697 O O . SER A 1 707 ? 84.682 104.885 27.575 1.00 27.85 ? 707 SER A O 1 ATOM 5698 C CB . SER A 1 707 ? 86.546 105.133 30.080 1.00 29.79 ? 707 SER A CB 1 ATOM 5699 O OG . SER A 1 707 ? 87.705 104.509 29.585 1.00 33.23 ? 707 SER A OG 1 ATOM 5700 N N . GLN A 1 708 ? 86.606 105.796 26.757 1.00 29.58 ? 708 GLN A N 1 ATOM 5701 C CA . GLN A 1 708 ? 86.464 105.158 25.426 1.00 30.95 ? 708 GLN A CA 1 ATOM 5702 C C . GLN A 1 708 ? 86.668 103.644 25.485 1.00 31.13 ? 708 GLN A C 1 ATOM 5703 O O . GLN A 1 708 ? 87.663 103.171 26.019 1.00 31.38 ? 708 GLN A O 1 ATOM 5704 C CB . GLN A 1 708 ? 87.423 105.772 24.392 1.00 31.30 ? 708 GLN A CB 1 ATOM 5705 C CG . GLN A 1 708 ? 87.131 105.300 22.972 1.00 30.10 ? 708 GLN A CG 1 ATOM 5706 C CD . GLN A 1 708 ? 88.025 105.921 21.915 1.00 32.07 ? 708 GLN A CD 1 ATOM 5707 O OE1 . GLN A 1 708 ? 88.630 106.971 22.130 1.00 32.07 ? 708 GLN A OE1 1 ATOM 5708 N NE2 . GLN A 1 708 ? 88.087 105.278 20.736 1.00 32.23 ? 708 GLN A NE2 1 ATOM 5709 N N . VAL A 1 709 ? 85.735 102.868 24.944 1.00 31.93 ? 709 VAL A N 1 ATOM 5710 C CA . VAL A 1 709 ? 85.915 101.411 25.000 1.00 32.62 ? 709 VAL A CA 1 ATOM 5711 C C . VAL A 1 709 ? 86.921 100.949 23.935 1.00 33.91 ? 709 VAL A C 1 ATOM 5712 O O . VAL A 1 709 ? 87.078 101.600 22.908 1.00 32.59 ? 709 VAL A O 1 ATOM 5713 C CB . VAL A 1 709 ? 84.580 100.634 24.915 1.00 32.79 ? 709 VAL A CB 1 ATOM 5714 C CG1 . VAL A 1 709 ? 83.561 101.312 25.763 1.00 32.37 ? 709 VAL A CG1 1 ATOM 5715 C CG2 . VAL A 1 709 ? 84.086 100.551 23.492 1.00 31.36 ? 709 VAL A CG2 1 ATOM 5716 N N . ARG A 1 710 ? 87.613 99.845 24.210 1.00 35.91 ? 710 ARG A N 1 ATOM 5717 C CA . ARG A 1 710 ? 88.654 99.349 23.315 1.00 39.40 ? 710 ARG A CA 1 ATOM 5718 C C . ARG A 1 710 ? 88.028 98.522 22.192 1.00 38.50 ? 710 ARG A C 1 ATOM 5719 O O . ARG A 1 710 ? 88.694 98.164 21.230 1.00 39.97 ? 710 ARG A O 1 ATOM 5720 C CB . ARG A 1 710 ? 89.702 98.521 24.088 1.00 39.39 ? 710 ARG A CB 1 ATOM 5721 C CG . ARG A 1 710 ? 91.044 99.280 24.310 1.00 43.43 ? 710 ARG A CG 1 ATOM 5722 C CD . ARG A 1 710 ? 92.048 98.510 25.202 1.00 45.20 ? 710 ARG A CD 1 ATOM 5723 N NE . ARG A 1 710 ? 91.729 98.611 26.640 1.00 55.18 ? 710 ARG A NE 1 ATOM 5724 C CZ . ARG A 1 710 ? 92.257 97.837 27.602 1.00 58.76 ? 710 ARG A CZ 1 ATOM 5725 N NH1 . ARG A 1 710 ? 93.146 96.876 27.304 1.00 59.62 ? 710 ARG A NH1 1 ATOM 5726 N NH2 . ARG A 1 710 ? 91.892 98.022 28.877 1.00 59.68 ? 710 ARG A NH2 1 ATOM 5727 N N . TRP A 1 711 ? 86.737 98.252 22.299 1.00 37.54 ? 711 TRP A N 1 ATOM 5728 C CA . TRP A 1 711 ? 86.058 97.367 21.355 1.00 36.42 ? 711 TRP A CA 1 ATOM 5729 C C . TRP A 1 711 ? 85.431 98.162 20.206 1.00 34.31 ? 711 TRP A C 1 ATOM 5730 O O . TRP A 1 711 ? 84.990 99.295 20.395 1.00 33.06 ? 711 TRP A O 1 ATOM 5731 C CB . TRP A 1 711 ? 84.986 96.565 22.081 1.00 37.83 ? 711 TRP A CB 1 ATOM 5732 C CG . TRP A 1 711 ? 85.423 95.951 23.390 1.00 40.50 ? 711 TRP A CG 1 ATOM 5733 C CD1 . TRP A 1 711 ? 86.521 95.162 23.602 1.00 42.04 ? 711 TRP A CD1 1 ATOM 5734 C CD2 . TRP A 1 711 ? 84.742 96.038 24.653 1.00 41.68 ? 711 TRP A CD2 1 ATOM 5735 N NE1 . TRP A 1 711 ? 86.574 94.773 24.914 1.00 43.69 ? 711 TRP A NE1 1 ATOM 5736 C CE2 . TRP A 1 711 ? 85.492 95.287 25.583 1.00 43.15 ? 711 TRP A CE2 1 ATOM 5737 C CE3 . TRP A 1 711 ? 83.571 96.681 25.086 1.00 43.69 ? 711 TRP A CE3 1 ATOM 5738 C CZ2 . TRP A 1 711 ? 85.113 95.158 26.939 1.00 42.57 ? 711 TRP A CZ2 1 ATOM 5739 C CZ3 . TRP A 1 711 ? 83.191 96.557 26.441 1.00 43.06 ? 711 TRP A CZ3 1 ATOM 5740 C CH2 . TRP A 1 711 ? 83.968 95.804 27.346 1.00 42.07 ? 711 TRP A CH2 1 ATOM 5741 N N . ARG A 1 712 ? 85.390 97.547 19.025 1.00 32.43 ? 712 ARG A N 1 ATOM 5742 C CA . ARG A 1 712 ? 84.766 98.134 17.846 1.00 30.64 ? 712 ARG A CA 1 ATOM 5743 C C . ARG A 1 712 ? 84.387 97.047 16.838 1.00 29.94 ? 712 ARG A C 1 ATOM 5744 O O . ARG A 1 712 ? 85.243 96.253 16.432 1.00 28.21 ? 712 ARG A O 1 ATOM 5745 C CB . ARG A 1 712 ? 85.712 99.144 17.190 1.00 30.18 ? 712 ARG A CB 1 ATOM 5746 C CG . ARG A 1 712 ? 85.095 99.815 15.990 1.00 29.58 ? 712 ARG A CG 1 ATOM 5747 C CD . ARG A 1 712 ? 85.667 101.184 15.693 1.00 31.19 ? 712 ARG A CD 1 ATOM 5748 N NE . ARG A 1 712 ? 84.952 101.825 14.584 1.00 28.71 ? 712 ARG A NE 1 ATOM 5749 C CZ . ARG A 1 712 ? 85.030 103.116 14.296 1.00 29.79 ? 712 ARG A CZ 1 ATOM 5750 N NH1 . ARG A 1 712 ? 85.771 103.915 15.049 1.00 30.24 ? 712 ARG A NH1 1 ATOM 5751 N NH2 . ARG A 1 712 ? 84.350 103.615 13.276 1.00 28.60 ? 712 ARG A NH2 1 ATOM 5752 N N . LYS A 1 713 ? 83.113 97.014 16.433 1.00 29.19 ? 713 LYS A N 1 ATOM 5753 C CA . LYS A 1 713 ? 82.646 96.050 15.418 1.00 29.16 ? 713 LYS A CA 1 ATOM 5754 C C . LYS A 1 713 ? 83.062 94.640 15.843 1.00 29.02 ? 713 LYS A C 1 ATOM 5755 O O . LYS A 1 713 ? 83.792 93.973 15.123 1.00 29.38 ? 713 LYS A O 1 ATOM 5756 C CB . LYS A 1 713 ? 83.224 96.402 14.028 1.00 28.82 ? 713 LYS A CB 1 ATOM 5757 C CG . LYS A 1 713 ? 82.455 95.831 12.825 1.00 29.54 ? 713 LYS A CG 1 ATOM 5758 C CD . LYS A 1 713 ? 83.145 96.107 11.463 1.00 29.85 ? 713 LYS A CD 1 ATOM 5759 C CE . LYS A 1 713 ? 82.201 95.733 10.276 1.00 31.32 ? 713 LYS A CE 1 ATOM 5760 N NZ . LYS A 1 713 ? 82.934 95.731 8.923 1.00 34.34 ? 713 LYS A NZ 1 ATOM 5761 N N . GLN A 1 714 ? 82.643 94.213 17.032 1.00 29.22 ? 714 GLN A N 1 ATOM 5762 C CA . GLN A 1 714 ? 82.966 92.872 17.548 1.00 30.44 ? 714 GLN A CA 1 ATOM 5763 C C . GLN A 1 714 ? 82.071 92.455 18.720 1.00 30.97 ? 714 GLN A C 1 ATOM 5764 O O . GLN A 1 714 ? 81.538 93.308 19.409 1.00 30.30 ? 714 GLN A O 1 ATOM 5765 C CB . GLN A 1 714 ? 84.435 92.786 17.972 1.00 30.90 ? 714 GLN A CB 1 ATOM 5766 C CG . GLN A 1 714 ? 84.841 93.809 19.014 1.00 32.47 ? 714 GLN A CG 1 ATOM 5767 C CD . GLN A 1 714 ? 86.337 93.876 19.182 1.00 38.44 ? 714 GLN A CD 1 ATOM 5768 O OE1 . GLN A 1 714 ? 87.021 92.846 19.190 1.00 41.29 ? 714 GLN A OE1 1 ATOM 5769 N NE2 . GLN A 1 714 ? 86.864 95.076 19.306 1.00 38.62 ? 714 GLN A NE2 1 ATOM 5770 N N . LYS A 1 715 ? 81.926 91.143 18.918 1.00 31.27 ? 715 LYS A N 1 ATOM 5771 C CA . LYS A 1 715 ? 81.263 90.561 20.083 1.00 33.36 ? 715 LYS A CA 1 ATOM 5772 C C . LYS A 1 715 ? 82.212 90.551 21.250 1.00 33.77 ? 715 LYS A C 1 ATOM 5773 O O . LYS A 1 715 ? 83.379 90.160 21.110 1.00 33.74 ? 715 LYS A O 1 ATOM 5774 C CB . LYS A 1 715 ? 80.782 89.122 19.827 1.00 33.58 ? 715 LYS A CB 1 ATOM 5775 C CG . LYS A 1 715 ? 79.276 89.015 19.565 1.00 37.12 ? 715 LYS A CG 1 ATOM 5776 C CD . LYS A 1 715 ? 78.681 87.653 19.958 1.00 39.79 ? 715 LYS A CD 1 ATOM 5777 C CE . LYS A 1 715 ? 77.161 87.806 20.234 1.00 44.65 ? 715 LYS A CE 1 ATOM 5778 N NZ . LYS A 1 715 ? 76.337 86.545 20.001 1.00 43.61 ? 715 LYS A NZ 1 ATOM 5779 N N . VAL A 1 716 ? 81.718 90.993 22.398 1.00 34.26 ? 716 VAL A N 1 ATOM 5780 C CA . VAL A 1 716 ? 82.545 91.078 23.611 1.00 35.23 ? 716 VAL A CA 1 ATOM 5781 C C . VAL A 1 716 ? 81.774 90.513 24.801 1.00 35.84 ? 716 VAL A C 1 ATOM 5782 O O . VAL A 1 716 ? 80.557 90.420 24.737 1.00 36.20 ? 716 VAL A O 1 ATOM 5783 C CB . VAL A 1 716 ? 82.956 92.543 23.914 1.00 35.29 ? 716 VAL A CB 1 ATOM 5784 C CG1 . VAL A 1 716 ? 83.524 93.236 22.650 1.00 34.62 ? 716 VAL A CG1 1 ATOM 5785 C CG2 . VAL A 1 716 ? 81.769 93.337 24.464 1.00 34.73 ? 716 VAL A CG2 1 ATOM 5786 N N . GLU A 1 717 ? 82.461 90.116 25.875 1.00 36.67 ? 717 GLU A N 1 ATOM 5787 C CA . GLU A 1 717 ? 81.747 89.915 27.147 1.00 37.35 ? 717 GLU A CA 1 ATOM 5788 C C . GLU A 1 717 ? 81.987 91.114 28.023 1.00 36.05 ? 717 GLU A C 1 ATOM 5789 O O . GLU A 1 717 ? 83.122 91.483 28.332 1.00 35.55 ? 717 GLU A O 1 ATOM 5790 C CB . GLU A 1 717 ? 82.063 88.597 27.849 1.00 38.18 ? 717 GLU A CB 1 ATOM 5791 C CG . GLU A 1 717 ? 83.493 88.401 28.267 1.00 42.80 ? 717 GLU A CG 1 ATOM 5792 C CD . GLU A 1 717 ? 83.623 87.260 29.265 1.00 49.18 ? 717 GLU A CD 1 ATOM 5793 O OE1 . GLU A 1 717 ? 83.191 86.105 28.944 1.00 50.72 ? 717 GLU A OE1 1 ATOM 5794 O OE2 . GLU A 1 717 ? 84.137 87.541 30.376 1.00 51.72 ? 717 GLU A OE2 1 ATOM 5795 N N . MET A 1 718 ? 80.885 91.769 28.349 1.00 35.16 ? 718 MET A N 1 ATOM 5796 C CA . MET A 1 718 ? 80.906 93.058 29.027 1.00 34.19 ? 718 MET A CA 1 ATOM 5797 C C . MET A 1 718 ? 80.726 92.695 30.482 1.00 32.86 ? 718 MET A C 1 ATOM 5798 O O . MET A 1 718 ? 79.799 91.944 30.805 1.00 32.39 ? 718 MET A O 1 ATOM 5799 C CB . MET A 1 718 ? 79.709 93.878 28.541 1.00 33.64 ? 718 MET A CB 1 ATOM 5800 C CG . MET A 1 718 ? 79.987 95.299 28.256 1.00 35.68 ? 718 MET A CG 1 ATOM 5801 S SD . MET A 1 718 ? 78.506 96.126 27.655 1.00 36.41 ? 718 MET A SD 1 ATOM 5802 C CE . MET A 1 718 ? 78.899 96.222 25.910 1.00 35.00 ? 718 MET A CE 1 ATOM 5803 N N . GLU A 1 719 ? 81.601 93.207 31.348 1.00 32.49 ? 719 GLU A N 1 ATOM 5804 C CA . GLU A 1 719 ? 81.533 92.913 32.778 1.00 32.64 ? 719 GLU A CA 1 ATOM 5805 C C . GLU A 1 719 ? 80.425 93.773 33.375 1.00 30.69 ? 719 GLU A C 1 ATOM 5806 O O . GLU A 1 719 ? 80.493 94.997 33.364 1.00 29.82 ? 719 GLU A O 1 ATOM 5807 C CB . GLU A 1 719 ? 82.851 93.225 33.500 1.00 34.04 ? 719 GLU A CB 1 ATOM 5808 C CG . GLU A 1 719 ? 82.955 92.520 34.897 1.00 41.13 ? 719 GLU A CG 1 ATOM 5809 C CD . GLU A 1 719 ? 83.731 93.314 35.964 1.00 49.41 ? 719 GLU A CD 1 ATOM 5810 O OE1 . GLU A 1 719 ? 84.791 93.925 35.624 1.00 52.04 ? 719 GLU A OE1 1 ATOM 5811 O OE2 . GLU A 1 719 ? 83.281 93.301 37.152 1.00 52.07 ? 719 GLU A OE2 1 ATOM 5812 N N . LEU A 1 720 ? 79.382 93.121 33.866 1.00 29.20 ? 720 LEU A N 1 ATOM 5813 C CA . LEU A 1 720 ? 78.239 93.850 34.412 1.00 27.61 ? 720 LEU A CA 1 ATOM 5814 C C . LEU A 1 720 ? 77.781 93.233 35.722 1.00 26.42 ? 720 LEU A C 1 ATOM 5815 O O . LEU A 1 720 ? 76.882 92.396 35.730 1.00 26.69 ? 720 LEU A O 1 ATOM 5816 C CB . LEU A 1 720 ? 77.086 93.948 33.398 1.00 27.40 ? 720 LEU A CB 1 ATOM 5817 C CG . LEU A 1 720 ? 77.342 94.674 32.094 1.00 27.21 ? 720 LEU A CG 1 ATOM 5818 C CD1 . LEU A 1 720 ? 76.198 94.369 31.146 1.00 25.41 ? 720 LEU A CD1 1 ATOM 5819 C CD2 . LEU A 1 720 ? 77.549 96.199 32.301 1.00 28.46 ? 720 LEU A CD2 1 ATOM 5820 N N . PRO A 1 721 ? 78.399 93.649 36.836 1.00 26.07 ? 721 PRO A N 1 ATOM 5821 C CA . PRO A 1 721 ? 78.039 93.150 38.162 1.00 26.02 ? 721 PRO A CA 1 ATOM 5822 C C . PRO A 1 721 ? 76.571 93.415 38.531 1.00 26.72 ? 721 PRO A C 1 ATOM 5823 O O . PRO A 1 721 ? 75.854 94.129 37.785 1.00 26.66 ? 721 PRO A O 1 ATOM 5824 C CB . PRO A 1 721 ? 78.943 93.955 39.091 1.00 26.33 ? 721 PRO A CB 1 ATOM 5825 C CG . PRO A 1 721 ? 80.037 94.484 38.245 1.00 26.16 ? 721 PRO A CG 1 ATOM 5826 C CD . PRO A 1 721 ? 79.522 94.616 36.876 1.00 26.14 ? 721 PRO A CD 1 ATOM 5827 N N . GLY A 1 722 ? 76.140 92.888 39.689 1.00 26.33 ? 722 GLY A N 1 ATOM 5828 C CA . GLY A 1 722 ? 74.740 92.981 40.145 1.00 26.06 ? 722 GLY A CA 1 ATOM 5829 C C . GLY A 1 722 ? 74.160 94.391 40.142 1.00 26.07 ? 722 GLY A C 1 ATOM 5830 O O . GLY A 1 722 ? 72.955 94.578 39.967 1.00 26.69 ? 722 GLY A O 1 ATOM 5831 N N . ASP A 1 723 ? 75.028 95.382 40.329 1.00 26.00 ? 723 ASP A N 1 ATOM 5832 C CA . ASP A 1 723 ? 74.635 96.780 40.385 1.00 26.52 ? 723 ASP A CA 1 ATOM 5833 C C . ASP A 1 723 ? 74.752 97.591 39.056 1.00 25.28 ? 723 ASP A C 1 ATOM 5834 O O . ASP A 1 723 ? 74.601 98.815 39.081 1.00 25.70 ? 723 ASP A O 1 ATOM 5835 C CB . ASP A 1 723 ? 75.400 97.480 41.523 1.00 27.53 ? 723 ASP A CB 1 ATOM 5836 C CG . ASP A 1 723 ? 76.919 97.523 41.292 1.00 31.07 ? 723 ASP A CG 1 ATOM 5837 O OD1 . ASP A 1 723 ? 77.493 96.708 40.504 1.00 32.79 ? 723 ASP A OD1 1 ATOM 5838 O OD2 . ASP A 1 723 ? 77.555 98.394 41.918 1.00 34.62 ? 723 ASP A OD2 1 ATOM 5839 N N . LYS A 1 724 ? 74.960 96.912 37.917 1.00 23.66 ? 724 LYS A N 1 ATOM 5840 C CA . LYS A 1 724 ? 75.192 97.580 36.631 1.00 22.64 ? 724 LYS A CA 1 ATOM 5841 C C . LYS A 1 724 ? 74.367 97.058 35.445 1.00 21.55 ? 724 LYS A C 1 ATOM 5842 O O . LYS A 1 724 ? 74.031 95.894 35.378 1.00 20.69 ? 724 LYS A O 1 ATOM 5843 C CB . LYS A 1 724 ? 76.687 97.487 36.256 1.00 23.44 ? 724 LYS A CB 1 ATOM 5844 C CG . LYS A 1 724 ? 77.670 98.058 37.280 1.00 24.48 ? 724 LYS A CG 1 ATOM 5845 C CD . LYS A 1 724 ? 77.573 99.600 37.403 1.00 27.76 ? 724 LYS A CD 1 ATOM 5846 C CE . LYS A 1 724 ? 78.606 100.186 38.375 1.00 28.47 ? 724 LYS A CE 1 ATOM 5847 N NZ . LYS A 1 724 ? 78.287 101.572 38.844 1.00 31.56 ? 724 LYS A NZ 1 ATOM 5848 N N . ILE A 1 725 ? 74.078 97.963 34.513 1.00 21.41 ? 725 ILE A N 1 ATOM 5849 C CA . ILE A 1 725 ? 73.622 97.693 33.135 1.00 20.20 ? 725 ILE A CA 1 ATOM 5850 C C . ILE A 1 725 ? 74.575 98.465 32.205 1.00 20.45 ? 725 ILE A C 1 ATOM 5851 O O . ILE A 1 725 ? 75.036 99.529 32.571 1.00 18.96 ? 725 ILE A O 1 ATOM 5852 C CB . ILE A 1 725 ? 72.201 98.217 32.948 1.00 20.16 ? 725 ILE A CB 1 ATOM 5853 C CG1 . ILE A 1 725 ? 71.716 98.075 31.501 1.00 19.44 ? 725 ILE A CG1 1 ATOM 5854 C CG2 . ILE A 1 725 ? 72.041 99.672 33.437 1.00 17.89 ? 725 ILE A CG2 1 ATOM 5855 C CD1 . ILE A 1 725 ? 70.209 97.958 31.419 1.00 16.13 ? 725 ILE A CD1 1 ATOM 5856 N N . GLY A 1 726 ? 74.892 97.933 31.018 1.00 21.27 ? 726 GLY A N 1 ATOM 5857 C CA . GLY A 1 726 ? 75.880 98.624 30.118 1.00 20.07 ? 726 GLY A CA 1 ATOM 5858 C C . GLY A 1 726 ? 75.193 99.801 29.468 1.00 19.67 ? 726 GLY A C 1 ATOM 5859 O O . GLY A 1 726 ? 74.056 99.688 28.976 1.00 18.52 ? 726 GLY A O 1 ATOM 5860 N N . LEU A 1 727 ? 75.838 100.951 29.531 1.00 19.06 ? 727 LEU A N 1 ATOM 5861 C CA . LEU A 1 727 ? 75.323 102.137 28.872 1.00 19.31 ? 727 LEU A CA 1 ATOM 5862 C C . LEU A 1 727 ? 76.502 102.763 28.148 1.00 18.76 ? 727 LEU A C 1 ATOM 5863 O O . LEU A 1 727 ? 77.486 103.116 28.800 1.00 18.08 ? 727 LEU A O 1 ATOM 5864 C CB . LEU A 1 727 ? 74.723 103.144 29.890 1.00 18.61 ? 727 LEU A CB 1 ATOM 5865 C CG . LEU A 1 727 ? 73.493 102.720 30.710 1.00 19.81 ? 727 LEU A CG 1 ATOM 5866 C CD1 . LEU A 1 727 ? 73.201 103.781 31.793 1.00 18.88 ? 727 LEU A CD1 1 ATOM 5867 C CD2 . LEU A 1 727 ? 72.262 102.521 29.811 1.00 15.20 ? 727 LEU A CD2 1 ATOM 5868 N N . HIS A 1 728 ? 76.399 102.917 26.824 1.00 17.57 ? 728 HIS A N 1 ATOM 5869 C CA . HIS A 1 728 ? 77.453 103.585 26.052 1.00 17.66 ? 728 HIS A CA 1 ATOM 5870 C C . HIS A 1 728 ? 76.908 104.652 25.126 1.00 17.95 ? 728 HIS A C 1 ATOM 5871 O O . HIS A 1 728 ? 75.812 104.502 24.563 1.00 17.81 ? 728 HIS A O 1 ATOM 5872 C CB . HIS A 1 728 ? 78.243 102.562 25.230 1.00 16.96 ? 728 HIS A CB 1 ATOM 5873 C CG . HIS A 1 728 ? 78.929 101.546 26.078 1.00 17.96 ? 728 HIS A CG 1 ATOM 5874 N ND1 . HIS A 1 728 ? 78.275 100.453 26.589 1.00 20.68 ? 728 HIS A ND1 1 ATOM 5875 C CD2 . HIS A 1 728 ? 80.192 101.494 26.564 1.00 19.75 ? 728 HIS A CD2 1 ATOM 5876 C CE1 . HIS A 1 728 ? 79.108 99.759 27.349 1.00 22.10 ? 728 HIS A CE1 1 ATOM 5877 N NE2 . HIS A 1 728 ? 80.283 100.362 27.338 1.00 20.14 ? 728 HIS A NE2 1 ATOM 5878 N N . LEU A 1 729 ? 77.697 105.707 24.979 1.00 17.51 ? 729 LEU A N 1 ATOM 5879 C CA . LEU A 1 729 ? 77.395 106.863 24.143 1.00 17.85 ? 729 LEU A CA 1 ATOM 5880 C C . LEU A 1 729 ? 78.237 106.806 22.906 1.00 18.49 ? 729 LEU A C 1 ATOM 5881 O O . LEU A 1 729 ? 79.457 106.516 22.989 1.00 17.93 ? 729 LEU A O 1 ATOM 5882 C CB . LEU A 1 729 ? 77.749 108.157 24.867 1.00 17.74 ? 729 LEU A CB 1 ATOM 5883 C CG . LEU A 1 729 ? 76.904 108.370 26.117 1.00 18.59 ? 729 LEU A CG 1 ATOM 5884 C CD1 . LEU A 1 729 ? 77.450 109.541 26.883 1.00 17.69 ? 729 LEU A CD1 1 ATOM 5885 C CD2 . LEU A 1 729 ? 75.443 108.581 25.784 1.00 17.05 ? 729 LEU A CD2 1 ATOM 5886 N N . ARG A 1 730 ? 77.584 107.099 21.776 1.00 17.54 ? 730 ARG A N 1 ATOM 5887 C CA . ARG A 1 730 ? 78.183 106.992 20.451 1.00 18.02 ? 730 ARG A CA 1 ATOM 5888 C C . ARG A 1 730 ? 79.021 108.247 20.100 1.00 17.90 ? 730 ARG A C 1 ATOM 5889 O O . ARG A 1 730 ? 78.545 109.395 20.249 1.00 17.16 ? 730 ARG A O 1 ATOM 5890 C CB . ARG A 1 730 ? 77.072 106.752 19.412 1.00 16.98 ? 730 ARG A CB 1 ATOM 5891 C CG . ARG A 1 730 ? 77.567 106.336 17.986 1.00 18.22 ? 730 ARG A CG 1 ATOM 5892 C CD . ARG A 1 730 ? 76.339 106.011 17.127 1.00 17.40 ? 730 ARG A CD 1 ATOM 5893 N NE . ARG A 1 730 ? 76.634 105.941 15.703 1.00 18.93 ? 730 ARG A NE 1 ATOM 5894 C CZ . ARG A 1 730 ? 75.711 105.936 14.756 1.00 20.14 ? 730 ARG A CZ 1 ATOM 5895 N NH1 . ARG A 1 730 ? 74.428 105.964 15.102 1.00 21.33 ? 730 ARG A NH1 1 ATOM 5896 N NH2 . ARG A 1 730 ? 76.066 105.887 13.466 1.00 17.47 ? 730 ARG A NH2 1 ATOM 5897 N N . GLY A 1 731 ? 80.277 108.024 19.692 1.00 17.60 ? 731 GLY A N 1 ATOM 5898 C CA . GLY A 1 731 ? 81.096 109.070 19.113 1.00 17.74 ? 731 GLY A CA 1 ATOM 5899 C C . GLY A 1 731 ? 80.406 109.724 17.931 1.00 18.49 ? 731 GLY A C 1 ATOM 5900 O O . GLY A 1 731 ? 79.919 109.057 17.038 1.00 19.59 ? 731 GLY A O 1 ATOM 5901 N N . GLY A 1 732 ? 80.358 111.044 17.925 1.00 18.48 ? 732 GLY A N 1 ATOM 5902 C CA . GLY A 1 732 ? 79.687 111.770 16.871 1.00 18.05 ? 732 GLY A CA 1 ATOM 5903 C C . GLY A 1 732 ? 78.416 112.459 17.310 1.00 18.40 ? 732 GLY A C 1 ATOM 5904 O O . GLY A 1 732 ? 77.827 113.203 16.527 1.00 19.50 ? 732 GLY A O 1 ATOM 5905 N N . TYR A 1 733 ? 77.997 112.243 18.555 1.00 18.49 ? 733 TYR A N 1 ATOM 5906 C CA . TYR A 1 733 ? 76.666 112.700 19.023 1.00 18.72 ? 733 TYR A CA 1 ATOM 5907 C C . TYR A 1 733 ? 76.786 113.527 20.284 1.00 18.58 ? 733 TYR A C 1 ATOM 5908 O O . TYR A 1 733 ? 77.638 113.267 21.099 1.00 18.49 ? 733 TYR A O 1 ATOM 5909 C CB . TYR A 1 733 ? 75.710 111.477 19.229 1.00 19.38 ? 733 TYR A CB 1 ATOM 5910 C CG . TYR A 1 733 ? 75.429 110.819 17.908 1.00 20.71 ? 733 TYR A CG 1 ATOM 5911 C CD1 . TYR A 1 733 ? 74.282 111.143 17.177 1.00 18.71 ? 733 TYR A CD1 1 ATOM 5912 C CD2 . TYR A 1 733 ? 76.369 109.953 17.336 1.00 19.43 ? 733 TYR A CD2 1 ATOM 5913 C CE1 . TYR A 1 733 ? 74.078 110.620 15.921 1.00 18.41 ? 733 TYR A CE1 1 ATOM 5914 C CE2 . TYR A 1 733 ? 76.161 109.421 16.076 1.00 21.92 ? 733 TYR A CE2 1 ATOM 5915 C CZ . TYR A 1 733 ? 75.000 109.760 15.396 1.00 20.14 ? 733 TYR A CZ 1 ATOM 5916 O OH . TYR A 1 733 ? 74.796 109.228 14.156 1.00 25.40 ? 733 TYR A OH 1 ATOM 5917 N N . ILE A 1 734 ? 75.911 114.512 20.417 1.00 18.72 ? 734 ILE A N 1 ATOM 5918 C CA . ILE A 1 734 ? 75.837 115.391 21.565 1.00 18.27 ? 734 ILE A CA 1 ATOM 5919 C C . ILE A 1 734 ? 74.454 115.184 22.222 1.00 18.77 ? 734 ILE A C 1 ATOM 5920 O O . ILE A 1 734 ? 73.418 115.249 21.541 1.00 17.69 ? 734 ILE A O 1 ATOM 5921 C CB . ILE A 1 734 ? 76.021 116.868 21.128 1.00 18.87 ? 734 ILE A CB 1 ATOM 5922 C CG1 . ILE A 1 734 ? 77.398 117.047 20.484 1.00 18.29 ? 734 ILE A CG1 1 ATOM 5923 C CG2 . ILE A 1 734 ? 75.835 117.864 22.292 1.00 17.20 ? 734 ILE A CG2 1 ATOM 5924 C CD1 . ILE A 1 734 ? 77.530 118.442 19.819 1.00 19.27 ? 734 ILE A CD1 1 ATOM 5925 N N . PHE A 1 735 ? 74.459 114.921 23.529 1.00 18.40 ? 735 PHE A N 1 ATOM 5926 C CA . PHE A 1 735 ? 73.247 114.550 24.277 1.00 18.55 ? 735 PHE A CA 1 ATOM 5927 C C . PHE A 1 735 ? 72.863 115.665 25.249 1.00 17.52 ? 735 PHE A C 1 ATOM 5928 O O . PHE A 1 735 ? 73.652 116.014 26.119 1.00 18.64 ? 735 PHE A O 1 ATOM 5929 C CB . PHE A 1 735 ? 73.482 113.233 25.039 1.00 18.60 ? 735 PHE A CB 1 ATOM 5930 C CG . PHE A 1 735 ? 74.017 112.115 24.170 1.00 19.01 ? 735 PHE A CG 1 ATOM 5931 C CD1 . PHE A 1 735 ? 73.179 111.113 23.702 1.00 18.58 ? 735 PHE A CD1 1 ATOM 5932 C CD2 . PHE A 1 735 ? 75.360 112.076 23.821 1.00 16.59 ? 735 PHE A CD2 1 ATOM 5933 C CE1 . PHE A 1 735 ? 73.671 110.069 22.890 1.00 16.66 ? 735 PHE A CE1 1 ATOM 5934 C CE2 . PHE A 1 735 ? 75.851 111.051 23.003 1.00 17.97 ? 735 PHE A CE2 1 ATOM 5935 C CZ . PHE A 1 735 ? 75.009 110.068 22.524 1.00 18.61 ? 735 PHE A CZ 1 ATOM 5936 N N . PRO A 1 736 ? 71.686 116.277 25.074 1.00 17.87 ? 736 PRO A N 1 ATOM 5937 C CA . PRO A 1 736 ? 71.287 117.234 26.118 1.00 17.23 ? 736 PRO A CA 1 ATOM 5938 C C . PRO A 1 736 ? 70.812 116.543 27.417 1.00 17.99 ? 736 PRO A C 1 ATOM 5939 O O . PRO A 1 736 ? 70.228 115.425 27.393 1.00 17.90 ? 736 PRO A O 1 ATOM 5940 C CB . PRO A 1 736 ? 70.140 118.011 25.466 1.00 17.17 ? 736 PRO A CB 1 ATOM 5941 C CG . PRO A 1 736 ? 69.501 117.017 24.504 1.00 17.76 ? 736 PRO A CG 1 ATOM 5942 C CD . PRO A 1 736 ? 70.692 116.193 23.978 1.00 17.47 ? 736 PRO A CD 1 ATOM 5943 N N . THR A 1 737 ? 71.073 117.197 28.551 1.00 17.79 ? 737 THR A N 1 ATOM 5944 C CA . THR A 1 737 ? 70.775 116.638 29.863 1.00 17.86 ? 737 THR A CA 1 ATOM 5945 C C . THR A 1 737 ? 70.193 117.736 30.762 1.00 18.22 ? 737 THR A C 1 ATOM 5946 O O . THR A 1 737 ? 70.288 118.929 30.461 1.00 19.03 ? 737 THR A O 1 ATOM 5947 C CB . THR A 1 737 ? 72.048 116.011 30.531 1.00 19.05 ? 737 THR A CB 1 ATOM 5948 O OG1 . THR A 1 737 ? 72.959 117.054 30.889 1.00 20.65 ? 737 THR A OG1 1 ATOM 5949 C CG2 . THR A 1 737 ? 72.797 115.066 29.582 1.00 16.49 ? 737 THR A CG2 1 ATOM 5950 N N . GLN A 1 738 ? 69.550 117.328 31.847 1.00 18.47 ? 738 GLN A N 1 ATOM 5951 C CA . GLN A 1 738 ? 69.100 118.252 32.847 1.00 18.71 ? 738 GLN A CA 1 ATOM 5952 C C . GLN A 1 738 ? 69.267 117.581 34.194 1.00 19.04 ? 738 GLN A C 1 ATOM 5953 O O . GLN A 1 738 ? 68.900 116.409 34.334 1.00 19.68 ? 738 GLN A O 1 ATOM 5954 C CB . GLN A 1 738 ? 67.656 118.642 32.561 1.00 19.15 ? 738 GLN A CB 1 ATOM 5955 C CG . GLN A 1 738 ? 67.086 119.709 33.519 1.00 18.86 ? 738 GLN A CG 1 ATOM 5956 C CD . GLN A 1 738 ? 65.804 120.312 32.956 1.00 19.29 ? 738 GLN A CD 1 ATOM 5957 O OE1 . GLN A 1 738 ? 64.947 119.588 32.433 1.00 18.46 ? 738 GLN A OE1 1 ATOM 5958 N NE2 . GLN A 1 738 ? 65.669 121.632 33.062 1.00 15.43 ? 738 GLN A NE2 1 ATOM 5959 N N . GLN A 1 739 ? 69.837 118.305 35.175 1.00 18.84 ? 739 GLN A N 1 ATOM 5960 C CA A GLN A 1 739 ? 70.071 117.766 36.515 0.50 19.42 ? 739 GLN A CA 1 ATOM 5961 C CA B GLN A 1 739 ? 70.069 117.750 36.505 0.50 18.49 ? 739 GLN A CA 1 ATOM 5962 C C . GLN A 1 739 ? 68.798 117.052 36.973 1.00 19.37 ? 739 GLN A C 1 ATOM 5963 O O . GLN A 1 739 ? 67.706 117.619 36.871 1.00 19.82 ? 739 GLN A O 1 ATOM 5964 C CB A GLN A 1 739 ? 70.425 118.884 37.506 0.50 19.31 ? 739 GLN A CB 1 ATOM 5965 C CB B GLN A 1 739 ? 70.435 118.849 37.495 0.50 18.16 ? 739 GLN A CB 1 ATOM 5966 C CG A GLN A 1 739 ? 71.680 119.706 37.156 0.50 20.05 ? 739 GLN A CG 1 ATOM 5967 C CG B GLN A 1 739 ? 70.588 118.362 38.922 0.50 15.40 ? 739 GLN A CG 1 ATOM 5968 C CD A GLN A 1 739 ? 72.348 120.325 38.393 0.50 20.50 ? 739 GLN A CD 1 ATOM 5969 C CD B GLN A 1 739 ? 70.807 119.488 39.893 0.50 13.43 ? 739 GLN A CD 1 ATOM 5970 O OE1 A GLN A 1 739 ? 71.932 120.068 39.529 0.50 21.38 ? 739 GLN A OE1 1 ATOM 5971 O OE1 B GLN A 1 739 ? 70.991 120.639 39.481 0.50 15.10 ? 739 GLN A OE1 1 ATOM 5972 N NE2 A GLN A 1 739 ? 73.397 121.128 38.173 0.50 19.50 ? 739 GLN A NE2 1 ATOM 5973 N NE2 B GLN A 1 739 ? 70.809 119.173 41.183 0.50 10.00 ? 739 GLN A NE2 1 ATOM 5974 N N . PRO A 1 740 ? 68.920 115.810 37.465 1.00 19.70 ? 740 PRO A N 1 ATOM 5975 C CA . PRO A 1 740 ? 67.618 115.168 37.780 1.00 20.88 ? 740 PRO A CA 1 ATOM 5976 C C . PRO A 1 740 ? 67.059 115.591 39.154 1.00 21.79 ? 740 PRO A C 1 ATOM 5977 O O . PRO A 1 740 ? 67.808 116.134 40.021 1.00 21.34 ? 740 PRO A O 1 ATOM 5978 C CB . PRO A 1 740 ? 67.969 113.682 37.815 1.00 20.62 ? 740 PRO A CB 1 ATOM 5979 C CG . PRO A 1 740 ? 69.403 113.662 38.356 1.00 21.07 ? 740 PRO A CG 1 ATOM 5980 C CD . PRO A 1 740 ? 70.068 114.940 37.778 1.00 19.71 ? 740 PRO A CD 1 ATOM 5981 N N . ASN A 1 741 ? 65.781 115.284 39.353 1.00 21.54 ? 741 ASN A N 1 ATOM 5982 C CA . ASN A 1 741 ? 65.093 115.401 40.646 1.00 22.12 ? 741 ASN A CA 1 ATOM 5983 C C . ASN A 1 741 ? 64.067 114.249 40.674 1.00 22.34 ? 741 ASN A C 1 ATOM 5984 O O . ASN A 1 741 ? 63.916 113.498 39.687 1.00 21.99 ? 741 ASN A O 1 ATOM 5985 C CB . ASN A 1 741 ? 64.381 116.760 40.788 1.00 21.69 ? 741 ASN A CB 1 ATOM 5986 C CG . ASN A 1 741 ? 64.242 117.216 42.262 1.00 24.54 ? 741 ASN A CG 1 ATOM 5987 O OD1 . ASN A 1 741 ? 64.391 116.423 43.196 1.00 27.08 ? 741 ASN A OD1 1 ATOM 5988 N ND2 . ASN A 1 741 ? 63.963 118.501 42.458 1.00 26.99 ? 741 ASN A ND2 1 ATOM 5989 N N . THR A 1 742 ? 63.348 114.114 41.780 1.00 21.47 ? 742 THR A N 1 ATOM 5990 C CA . THR A 1 742 ? 62.490 112.951 41.953 1.00 21.98 ? 742 THR A CA 1 ATOM 5991 C C . THR A 1 742 ? 61.158 113.093 41.210 1.00 21.28 ? 742 THR A C 1 ATOM 5992 O O . THR A 1 742 ? 60.387 112.142 41.173 1.00 23.06 ? 742 THR A O 1 ATOM 5993 C CB . THR A 1 742 ? 62.243 112.689 43.431 1.00 22.09 ? 742 THR A CB 1 ATOM 5994 O OG1 . THR A 1 742 ? 61.597 113.826 43.977 1.00 24.48 ? 742 THR A OG1 1 ATOM 5995 C CG2 . THR A 1 742 ? 63.547 112.494 44.173 1.00 22.92 ? 742 THR A CG2 1 ATOM 5996 N N . THR A 1 743 ? 60.885 114.279 40.655 1.00 20.59 ? 743 THR A N 1 ATOM 5997 C CA . THR A 1 743 ? 59.747 114.515 39.723 1.00 20.60 ? 743 THR A CA 1 ATOM 5998 C C . THR A 1 743 ? 60.225 115.372 38.542 1.00 19.71 ? 743 THR A C 1 ATOM 5999 O O . THR A 1 743 ? 61.158 116.151 38.669 1.00 19.32 ? 743 THR A O 1 ATOM 6000 C CB . THR A 1 743 ? 58.510 115.216 40.394 1.00 19.96 ? 743 THR A CB 1 ATOM 6001 O OG1 . THR A 1 743 ? 58.854 116.570 40.734 1.00 22.44 ? 743 THR A OG1 1 ATOM 6002 C CG2 . THR A 1 743 ? 58.059 114.486 41.682 1.00 19.19 ? 743 THR A CG2 1 ATOM 6003 N N . THR A 1 744 ? 59.596 115.200 37.391 1.00 20.29 ? 744 THR A N 1 ATOM 6004 C CA . THR A 1 744 ? 59.847 116.061 36.252 1.00 20.20 ? 744 THR A CA 1 ATOM 6005 C C . THR A 1 744 ? 59.244 117.451 36.467 1.00 20.97 ? 744 THR A C 1 ATOM 6006 O O . THR A 1 744 ? 59.772 118.412 35.935 1.00 20.76 ? 744 THR A O 1 ATOM 6007 C CB . THR A 1 744 ? 59.334 115.446 34.908 1.00 21.49 ? 744 THR A CB 1 ATOM 6008 O OG1 . THR A 1 744 ? 57.909 115.415 34.923 1.00 20.38 ? 744 THR A OG1 1 ATOM 6009 C CG2 . THR A 1 744 ? 59.869 113.962 34.676 1.00 17.44 ? 744 THR A CG2 1 ATOM 6010 N N . LEU A 1 745 ? 58.152 117.577 37.234 1.00 21.15 ? 745 LEU A N 1 ATOM 6011 C CA . LEU A 1 745 ? 57.682 118.930 37.586 1.00 21.26 ? 745 LEU A CA 1 ATOM 6012 C C . LEU A 1 745 ? 58.849 119.780 38.122 1.00 21.16 ? 745 LEU A C 1 ATOM 6013 O O . LEU A 1 745 ? 59.035 120.913 37.691 1.00 20.77 ? 745 LEU A O 1 ATOM 6014 C CB . LEU A 1 745 ? 56.569 118.912 38.622 1.00 21.52 ? 745 LEU A CB 1 ATOM 6015 C CG . LEU A 1 745 ? 56.071 120.296 39.092 1.00 23.50 ? 745 LEU A CG 1 ATOM 6016 C CD1 . LEU A 1 745 ? 55.268 121.006 38.001 1.00 25.12 ? 745 LEU A CD1 1 ATOM 6017 C CD2 . LEU A 1 745 ? 55.229 120.180 40.349 1.00 22.42 ? 745 LEU A CD2 1 ATOM 6018 N N . ALA A 1 746 ? 59.628 119.222 39.041 1.00 20.72 ? 746 ALA A N 1 ATOM 6019 C CA . ALA A 1 746 ? 60.799 119.934 39.558 1.00 21.55 ? 746 ALA A CA 1 ATOM 6020 C C . ALA A 1 746 ? 62.019 119.870 38.617 1.00 21.87 ? 746 ALA A C 1 ATOM 6021 O O . ALA A 1 746 ? 62.768 120.844 38.491 1.00 22.02 ? 746 ALA A O 1 ATOM 6022 C CB . ALA A 1 746 ? 61.175 119.373 40.920 1.00 21.42 ? 746 ALA A CB 1 ATOM 6023 N N . SER A 1 747 ? 62.249 118.721 37.977 1.00 21.63 ? 747 SER A N 1 ATOM 6024 C CA . SER A 1 747 ? 63.538 118.507 37.301 1.00 21.93 ? 747 SER A CA 1 ATOM 6025 C C . SER A 1 747 ? 63.619 119.443 36.107 1.00 21.92 ? 747 SER A C 1 ATOM 6026 O O . SER A 1 747 ? 64.700 119.911 35.770 1.00 22.01 ? 747 SER A O 1 ATOM 6027 C CB . SER A 1 747 ? 63.757 117.033 36.915 1.00 22.14 ? 747 SER A CB 1 ATOM 6028 O OG . SER A 1 747 ? 62.948 116.681 35.803 1.00 24.73 ? 747 SER A OG 1 ATOM 6029 N N . ARG A 1 748 ? 62.454 119.752 35.518 1.00 21.32 ? 748 ARG A N 1 ATOM 6030 C CA . ARG A 1 748 ? 62.337 120.691 34.404 1.00 20.80 ? 748 ARG A CA 1 ATOM 6031 C C . ARG A 1 748 ? 62.762 122.126 34.741 1.00 21.05 ? 748 ARG A C 1 ATOM 6032 O O . ARG A 1 748 ? 63.042 122.916 33.839 1.00 20.55 ? 748 ARG A O 1 ATOM 6033 C CB . ARG A 1 748 ? 60.904 120.718 33.871 1.00 21.17 ? 748 ARG A CB 1 ATOM 6034 C CG . ARG A 1 748 ? 60.546 119.576 32.898 1.00 20.90 ? 748 ARG A CG 1 ATOM 6035 C CD . ARG A 1 748 ? 59.095 119.657 32.494 1.00 19.55 ? 748 ARG A CD 1 ATOM 6036 N NE . ARG A 1 748 ? 58.827 120.899 31.782 1.00 19.66 ? 748 ARG A NE 1 ATOM 6037 C CZ . ARG A 1 748 ? 58.996 121.064 30.476 1.00 22.08 ? 748 ARG A CZ 1 ATOM 6038 N NH1 . ARG A 1 748 ? 59.390 120.043 29.723 1.00 25.70 ? 748 ARG A NH1 1 ATOM 6039 N NH2 . ARG A 1 748 ? 58.750 122.246 29.913 1.00 21.27 ? 748 ARG A NH2 1 ATOM 6040 N N . LYS A 1 749 ? 62.789 122.465 36.025 1.00 21.63 ? 749 LYS A N 1 ATOM 6041 C CA . LYS A 1 749 ? 63.305 123.779 36.472 1.00 23.06 ? 749 LYS A CA 1 ATOM 6042 C C . LYS A 1 749 ? 64.847 123.832 36.644 1.00 22.03 ? 749 LYS A C 1 ATOM 6043 O O . LYS A 1 749 ? 65.390 124.881 36.942 1.00 22.12 ? 749 LYS A O 1 ATOM 6044 C CB . LYS A 1 749 ? 62.597 124.225 37.770 1.00 23.32 ? 749 LYS A CB 1 ATOM 6045 C CG . LYS A 1 749 ? 61.053 124.338 37.626 1.00 25.73 ? 749 LYS A CG 1 ATOM 6046 C CD . LYS A 1 749 ? 60.383 124.489 38.991 1.00 26.20 ? 749 LYS A CD 1 ATOM 6047 C CE . LYS A 1 749 ? 58.829 124.475 38.899 1.00 31.45 ? 749 LYS A CE 1 ATOM 6048 N NZ . LYS A 1 749 ? 58.119 124.375 40.265 1.00 31.27 ? 749 LYS A NZ 1 ATOM 6049 N N . ASN A 1 750 ? 65.542 122.706 36.465 1.00 22.14 ? 750 ASN A N 1 ATOM 6050 C CA . ASN A 1 750 ? 66.971 122.591 36.839 1.00 21.75 ? 750 ASN A CA 1 ATOM 6051 C C . ASN A 1 750 ? 67.931 123.020 35.734 1.00 21.76 ? 750 ASN A C 1 ATOM 6052 O O . ASN A 1 750 ? 67.529 123.118 34.575 1.00 20.88 ? 750 ASN A O 1 ATOM 6053 C CB . ASN A 1 750 ? 67.331 121.155 37.296 1.00 22.13 ? 750 ASN A CB 1 ATOM 6054 C CG . ASN A 1 750 ? 66.932 120.854 38.757 1.00 21.34 ? 750 ASN A CG 1 ATOM 6055 O OD1 . ASN A 1 750 ? 66.781 121.745 39.574 1.00 24.54 ? 750 ASN A OD1 1 ATOM 6056 N ND2 . ASN A 1 750 ? 66.759 119.587 39.069 1.00 20.38 ? 750 ASN A ND2 1 ATOM 6057 N N . PRO A 1 751 ? 69.220 123.272 36.089 1.00 23.30 ? 751 PRO A N 1 ATOM 6058 C CA . PRO A 1 751 ? 70.267 123.536 35.089 1.00 23.76 ? 751 PRO A CA 1 ATOM 6059 C C . PRO A 1 751 ? 70.396 122.409 34.040 1.00 24.44 ? 751 PRO A C 1 ATOM 6060 O O . PRO A 1 751 ? 70.263 121.227 34.373 1.00 24.87 ? 751 PRO A O 1 ATOM 6061 C CB . PRO A 1 751 ? 71.553 123.579 35.936 1.00 24.44 ? 751 PRO A CB 1 ATOM 6062 C CG . PRO A 1 751 ? 71.083 124.073 37.305 1.00 24.57 ? 751 PRO A CG 1 ATOM 6063 C CD . PRO A 1 751 ? 69.751 123.347 37.474 1.00 23.53 ? 751 PRO A CD 1 ATOM 6064 N N . LEU A 1 752 ? 70.672 122.789 32.798 1.00 24.45 ? 752 LEU A N 1 ATOM 6065 C CA . LEU A 1 752 ? 70.912 121.836 31.718 1.00 24.81 ? 752 LEU A CA 1 ATOM 6066 C C . LEU A 1 752 ? 72.403 121.531 31.576 1.00 24.55 ? 752 LEU A C 1 ATOM 6067 O O . LEU A 1 752 ? 73.266 122.233 32.143 1.00 24.32 ? 752 LEU A O 1 ATOM 6068 C CB . LEU A 1 752 ? 70.345 122.378 30.384 1.00 24.67 ? 752 LEU A CB 1 ATOM 6069 C CG . LEU A 1 752 ? 68.863 122.775 30.333 1.00 27.20 ? 752 LEU A CG 1 ATOM 6070 C CD1 . LEU A 1 752 ? 68.640 123.958 29.366 1.00 25.42 ? 752 LEU A CD1 1 ATOM 6071 C CD2 . LEU A 1 752 ? 68.000 121.587 29.947 1.00 29.68 ? 752 LEU A CD2 1 ATOM 6072 N N . GLY A 1 753 ? 72.703 120.490 30.804 1.00 23.77 ? 753 GLY A N 1 ATOM 6073 C CA . GLY A 1 753 ? 74.082 120.143 30.468 1.00 22.92 ? 753 GLY A CA 1 ATOM 6074 C C . GLY A 1 753 ? 74.188 119.609 29.053 1.00 22.60 ? 753 GLY A C 1 ATOM 6075 O O . GLY A 1 753 ? 73.184 119.396 28.377 1.00 21.48 ? 753 GLY A O 1 ATOM 6076 N N . LEU A 1 754 ? 75.418 119.424 28.589 1.00 22.40 ? 754 LEU A N 1 ATOM 6077 C CA . LEU A 1 754 ? 75.680 118.744 27.299 1.00 22.74 ? 754 LEU A CA 1 ATOM 6078 C C . LEU A 1 754 ? 76.697 117.664 27.524 1.00 21.56 ? 754 LEU A C 1 ATOM 6079 O O . LEU A 1 754 ? 77.643 117.884 28.232 1.00 21.02 ? 754 LEU A O 1 ATOM 6080 C CB . LEU A 1 754 ? 76.231 119.701 26.235 1.00 21.87 ? 754 LEU A CB 1 ATOM 6081 C CG . LEU A 1 754 ? 75.251 120.763 25.773 1.00 22.12 ? 754 LEU A CG 1 ATOM 6082 C CD1 . LEU A 1 754 ? 75.961 121.739 24.840 1.00 22.48 ? 754 LEU A CD1 1 ATOM 6083 C CD2 . LEU A 1 754 ? 74.024 120.148 25.088 1.00 20.37 ? 754 LEU A CD2 1 ATOM 6084 N N . ILE A 1 755 ? 76.459 116.487 26.962 1.00 21.14 ? 755 ILE A N 1 ATOM 6085 C CA . ILE A 1 755 ? 77.508 115.479 26.861 1.00 21.15 ? 755 ILE A CA 1 ATOM 6086 C C . ILE A 1 755 ? 77.928 115.426 25.384 1.00 21.45 ? 755 ILE A C 1 ATOM 6087 O O . ILE A 1 755 ? 77.133 115.041 24.522 1.00 21.55 ? 755 ILE A O 1 ATOM 6088 C CB . ILE A 1 755 ? 77.094 114.081 27.374 1.00 19.54 ? 755 ILE A CB 1 ATOM 6089 C CG1 . ILE A 1 755 ? 76.656 114.175 28.831 1.00 19.84 ? 755 ILE A CG1 1 ATOM 6090 C CG2 . ILE A 1 755 ? 78.287 113.082 27.246 1.00 21.95 ? 755 ILE A CG2 1 ATOM 6091 C CD1 . ILE A 1 755 ? 76.030 112.885 29.393 1.00 22.06 ? 755 ILE A CD1 1 ATOM 6092 N N . ILE A 1 756 ? 79.159 115.843 25.101 1.00 21.22 ? 756 ILE A N 1 ATOM 6093 C CA . ILE A 1 756 ? 79.695 115.766 23.751 1.00 22.13 ? 756 ILE A CA 1 ATOM 6094 C C . ILE A 1 756 ? 80.571 114.511 23.596 1.00 22.84 ? 756 ILE A C 1 ATOM 6095 O O . ILE A 1 756 ? 81.683 114.447 24.136 1.00 21.95 ? 756 ILE A O 1 ATOM 6096 C CB . ILE A 1 756 ? 80.488 117.051 23.435 1.00 21.96 ? 756 ILE A CB 1 ATOM 6097 C CG1 . ILE A 1 756 ? 79.588 118.293 23.605 1.00 22.68 ? 756 ILE A CG1 1 ATOM 6098 C CG2 . ILE A 1 756 ? 81.117 116.988 22.027 1.00 24.13 ? 756 ILE A CG2 1 ATOM 6099 C CD1 . ILE A 1 756 ? 80.320 119.654 23.558 1.00 22.38 ? 756 ILE A CD1 1 ATOM 6100 N N . ALA A 1 757 ? 80.084 113.502 22.864 1.00 23.38 ? 757 ALA A N 1 ATOM 6101 C CA . ALA A 1 757 ? 80.939 112.337 22.581 1.00 22.99 ? 757 ALA A CA 1 ATOM 6102 C C . ALA A 1 757 ? 81.641 112.479 21.216 1.00 23.32 ? 757 ALA A C 1 ATOM 6103 O O . ALA A 1 757 ? 81.014 112.373 20.154 1.00 23.50 ? 757 ALA A O 1 ATOM 6104 C CB . ALA A 1 757 ? 80.141 111.065 22.637 1.00 22.49 ? 757 ALA A CB 1 ATOM 6105 N N . LEU A 1 758 ? 82.942 112.711 21.224 1.00 24.01 ? 758 LEU A N 1 ATOM 6106 C CA . LEU A 1 758 ? 83.645 113.025 19.961 1.00 24.27 ? 758 LEU A CA 1 ATOM 6107 C C . LEU A 1 758 ? 83.837 111.788 19.090 1.00 24.67 ? 758 LEU A C 1 ATOM 6108 O O . LEU A 1 758 ? 84.030 110.677 19.601 1.00 24.64 ? 758 LEU A O 1 ATOM 6109 C CB . LEU A 1 758 ? 84.983 113.745 20.232 1.00 24.08 ? 758 LEU A CB 1 ATOM 6110 C CG . LEU A 1 758 ? 84.852 115.132 20.903 1.00 23.77 ? 758 LEU A CG 1 ATOM 6111 C CD1 . LEU A 1 758 ? 86.213 115.716 21.132 1.00 22.88 ? 758 LEU A CD1 1 ATOM 6112 C CD2 . LEU A 1 758 ? 83.986 116.096 20.090 1.00 21.73 ? 758 LEU A CD2 1 ATOM 6113 N N . ASP A 1 759 ? 83.783 111.971 17.777 1.00 26.28 ? 759 ASP A N 1 ATOM 6114 C CA . ASP A 1 759 ? 84.156 110.869 16.859 1.00 27.96 ? 759 ASP A CA 1 ATOM 6115 C C . ASP A 1 759 ? 85.648 110.953 16.536 1.00 29.40 ? 759 ASP A C 1 ATOM 6116 O O . ASP A 1 759 ? 86.352 111.789 17.114 1.00 29.39 ? 759 ASP A O 1 ATOM 6117 C CB . ASP A 1 759 ? 83.262 110.863 15.609 1.00 27.62 ? 759 ASP A CB 1 ATOM 6118 C CG . ASP A 1 759 ? 83.470 112.076 14.717 1.00 29.86 ? 759 ASP A CG 1 ATOM 6119 O OD1 . ASP A 1 759 ? 84.479 112.812 14.888 1.00 28.54 ? 759 ASP A OD1 1 ATOM 6120 O OD2 . ASP A 1 759 ? 82.611 112.295 13.818 1.00 31.41 ? 759 ASP A OD2 1 ATOM 6121 N N . GLU A 1 760 ? 86.137 110.105 15.630 1.00 31.10 ? 760 GLU A N 1 ATOM 6122 C CA . GLU A 1 760 ? 87.580 110.051 15.296 1.00 32.81 ? 760 GLU A CA 1 ATOM 6123 C C . GLU A 1 760 ? 88.133 111.370 14.753 1.00 32.80 ? 760 GLU A C 1 ATOM 6124 O O . GLU A 1 760 ? 89.319 111.644 14.892 1.00 32.54 ? 760 GLU A O 1 ATOM 6125 C CB . GLU A 1 760 ? 87.900 108.931 14.299 1.00 33.42 ? 760 GLU A CB 1 ATOM 6126 C CG . GLU A 1 760 ? 87.275 107.581 14.591 1.00 38.41 ? 760 GLU A CG 1 ATOM 6127 C CD . GLU A 1 760 ? 85.940 107.389 13.864 1.00 43.66 ? 760 GLU A CD 1 ATOM 6128 O OE1 . GLU A 1 760 ? 85.852 106.411 13.093 1.00 45.28 ? 760 GLU A OE1 1 ATOM 6129 O OE2 . GLU A 1 760 ? 84.994 108.213 14.039 1.00 45.63 ? 760 GLU A OE2 1 ATOM 6130 N N . ASN A 1 761 ? 87.270 112.188 14.146 1.00 32.48 ? 761 ASN A N 1 ATOM 6131 C CA . ASN A 1 761 ? 87.699 113.476 13.639 1.00 32.40 ? 761 ASN A CA 1 ATOM 6132 C C . ASN A 1 761 ? 87.479 114.598 14.636 1.00 31.59 ? 761 ASN A C 1 ATOM 6133 O O . ASN A 1 761 ? 87.691 115.769 14.287 1.00 31.72 ? 761 ASN A O 1 ATOM 6134 C CB . ASN A 1 761 ? 87.020 113.821 12.307 1.00 33.22 ? 761 ASN A CB 1 ATOM 6135 C CG . ASN A 1 761 ? 87.080 112.672 11.301 1.00 36.69 ? 761 ASN A CG 1 ATOM 6136 O OD1 . ASN A 1 761 ? 88.081 111.941 11.217 1.00 41.27 ? 761 ASN A OD1 1 ATOM 6137 N ND2 . ASN A 1 761 ? 85.990 112.485 10.556 1.00 40.09 ? 761 ASN A ND2 1 ATOM 6138 N N . LYS A 1 762 ? 87.097 114.246 15.876 1.00 29.93 ? 762 LYS A N 1 ATOM 6139 C CA . LYS A 1 762 ? 86.837 115.236 16.947 1.00 28.66 ? 762 LYS A CA 1 ATOM 6140 C C . LYS A 1 762 ? 85.641 116.111 16.597 1.00 28.50 ? 762 LYS A C 1 ATOM 6141 O O . LYS A 1 762 ? 85.605 117.313 16.897 1.00 27.93 ? 762 LYS A O 1 ATOM 6142 C CB . LYS A 1 762 ? 88.063 116.103 17.303 1.00 30.31 ? 762 LYS A CB 1 ATOM 6143 C CG . LYS A 1 762 ? 89.405 115.367 17.598 1.00 29.31 ? 762 LYS A CG 1 ATOM 6144 C CD . LYS A 1 762 ? 89.243 114.172 18.565 1.00 35.02 ? 762 LYS A CD 1 ATOM 6145 C CE . LYS A 1 762 ? 90.454 113.197 18.475 1.00 37.39 ? 762 LYS A CE 1 ATOM 6146 N NZ . LYS A 1 762 ? 90.140 111.883 19.131 1.00 41.60 ? 762 LYS A NZ 1 ATOM 6147 N N . GLU A 1 763 ? 84.639 115.480 15.971 1.00 27.68 ? 763 GLU A N 1 ATOM 6148 C CA . GLU A 1 763 ? 83.373 116.140 15.612 1.00 27.05 ? 763 GLU A CA 1 ATOM 6149 C C . GLU A 1 763 ? 82.186 115.434 16.280 1.00 24.65 ? 763 GLU A C 1 ATOM 6150 O O . GLU A 1 763 ? 82.272 114.264 16.677 1.00 23.15 ? 763 GLU A O 1 ATOM 6151 C CB . GLU A 1 763 ? 83.199 116.199 14.072 1.00 26.13 ? 763 GLU A CB 1 ATOM 6152 C CG . GLU A 1 763 ? 84.369 116.953 13.425 1.00 30.84 ? 763 GLU A CG 1 ATOM 6153 C CD . GLU A 1 763 ? 84.206 117.281 11.942 1.00 31.88 ? 763 GLU A CD 1 ATOM 6154 O OE1 . GLU A 1 763 ? 83.652 116.472 11.179 1.00 39.22 ? 763 GLU A OE1 1 ATOM 6155 O OE2 . GLU A 1 763 ? 84.676 118.365 11.530 1.00 40.26 ? 763 GLU A OE2 1 ATOM 6156 N N . ALA A 1 764 ? 81.081 116.166 16.400 1.00 23.27 ? 764 ALA A N 1 ATOM 6157 C CA . ALA A 1 764 ? 79.877 115.651 17.044 1.00 21.54 ? 764 ALA A CA 1 ATOM 6158 C C . ALA A 1 764 ? 78.713 116.583 16.688 1.00 21.30 ? 764 ALA A C 1 ATOM 6159 O O . ALA A 1 764 ? 78.931 117.744 16.350 1.00 21.30 ? 764 ALA A O 1 ATOM 6160 C CB . ALA A 1 764 ? 80.086 115.554 18.546 1.00 20.47 ? 764 ALA A CB 1 ATOM 6161 N N . LYS A 1 765 ? 77.486 116.072 16.751 1.00 20.58 ? 765 LYS A N 1 ATOM 6162 C CA . LYS A 1 765 ? 76.306 116.843 16.435 1.00 21.18 ? 765 LYS A CA 1 ATOM 6163 C C . LYS A 1 765 ? 75.163 116.361 17.336 1.00 20.19 ? 765 LYS A C 1 ATOM 6164 O O . LYS A 1 765 ? 75.113 115.193 17.678 1.00 19.45 ? 765 LYS A O 1 ATOM 6165 C CB . LYS A 1 765 ? 75.907 116.600 14.980 1.00 21.90 ? 765 LYS A CB 1 ATOM 6166 C CG . LYS A 1 765 ? 75.679 117.851 14.176 1.00 28.76 ? 765 LYS A CG 1 ATOM 6167 C CD . LYS A 1 765 ? 76.326 117.694 12.754 1.00 38.49 ? 765 LYS A CD 1 ATOM 6168 C CE . LYS A 1 765 ? 76.991 119.000 12.247 1.00 41.84 ? 765 LYS A CE 1 ATOM 6169 N NZ . LYS A 1 765 ? 76.133 119.854 11.321 1.00 44.04 ? 765 LYS A NZ 1 ATOM 6170 N N . GLY A 1 766 ? 74.249 117.259 17.702 1.00 18.58 ? 766 GLY A N 1 ATOM 6171 C CA . GLY A 1 766 ? 73.057 116.837 18.441 1.00 19.08 ? 766 GLY A CA 1 ATOM 6172 C C . GLY A 1 766 ? 72.032 117.940 18.340 1.00 19.42 ? 766 GLY A C 1 ATOM 6173 O O . GLY A 1 766 ? 72.237 118.911 17.625 1.00 18.97 ? 766 GLY A O 1 ATOM 6174 N N . GLU A 1 767 ? 70.929 117.795 19.054 1.00 20.14 ? 767 GLU A N 1 ATOM 6175 C CA . GLU A 1 767 ? 69.839 118.775 18.978 1.00 21.21 ? 767 GLU A CA 1 ATOM 6176 C C . GLU A 1 767 ? 69.035 118.720 20.281 1.00 19.48 ? 767 GLU A C 1 ATOM 6177 O O . GLU A 1 767 ? 69.182 117.783 21.050 1.00 18.78 ? 767 GLU A O 1 ATOM 6178 C CB . GLU A 1 767 ? 68.954 118.473 17.774 1.00 21.28 ? 767 GLU A CB 1 ATOM 6179 C CG . GLU A 1 767 ? 68.188 117.133 17.900 1.00 24.82 ? 767 GLU A CG 1 ATOM 6180 C CD . GLU A 1 767 ? 67.469 116.726 16.608 1.00 26.04 ? 767 GLU A CD 1 ATOM 6181 O OE1 . GLU A 1 767 ? 67.664 117.435 15.605 1.00 33.90 ? 767 GLU A OE1 1 ATOM 6182 O OE2 . GLU A 1 767 ? 66.707 115.726 16.587 1.00 26.15 ? 767 GLU A OE2 1 ATOM 6183 N N . LEU A 1 768 ? 68.229 119.745 20.532 1.00 19.26 ? 768 LEU A N 1 ATOM 6184 C CA . LEU A 1 768 ? 67.331 119.795 21.676 1.00 18.99 ? 768 LEU A CA 1 ATOM 6185 C C . LEU A 1 768 ? 65.985 120.452 21.305 1.00 18.64 ? 768 LEU A C 1 ATOM 6186 O O . LEU A 1 768 ? 65.923 121.565 20.768 1.00 18.47 ? 768 LEU A O 1 ATOM 6187 C CB . LEU A 1 768 ? 67.993 120.546 22.858 1.00 19.09 ? 768 LEU A CB 1 ATOM 6188 C CG . LEU A 1 768 ? 67.105 120.857 24.072 1.00 18.89 ? 768 LEU A CG 1 ATOM 6189 C CD1 . LEU A 1 768 ? 66.561 119.608 24.745 1.00 16.57 ? 768 LEU A CD1 1 ATOM 6190 C CD2 . LEU A 1 768 ? 67.843 121.676 25.088 1.00 19.71 ? 768 LEU A CD2 1 ATOM 6191 N N . PHE A 1 769 ? 64.908 119.737 21.590 1.00 18.29 ? 769 PHE A N 1 ATOM 6192 C CA . PHE A 1 769 ? 63.573 120.262 21.442 1.00 17.78 ? 769 PHE A CA 1 ATOM 6193 C C . PHE A 1 769 ? 63.108 120.682 22.820 1.00 17.81 ? 769 PHE A C 1 ATOM 6194 O O . PHE A 1 769 ? 63.313 119.965 23.794 1.00 18.42 ? 769 PHE A O 1 ATOM 6195 C CB . PHE A 1 769 ? 62.643 119.166 20.863 1.00 17.36 ? 769 PHE A CB 1 ATOM 6196 C CG . PHE A 1 769 ? 61.173 119.514 20.905 1.00 17.47 ? 769 PHE A CG 1 ATOM 6197 C CD1 . PHE A 1 769 ? 60.606 120.299 19.912 1.00 17.48 ? 769 PHE A CD1 1 ATOM 6198 C CD2 . PHE A 1 769 ? 60.358 119.025 21.908 1.00 18.74 ? 769 PHE A CD2 1 ATOM 6199 C CE1 . PHE A 1 769 ? 59.255 120.587 19.925 1.00 18.77 ? 769 PHE A CE1 1 ATOM 6200 C CE2 . PHE A 1 769 ? 58.997 119.320 21.923 1.00 18.85 ? 769 PHE A CE2 1 ATOM 6201 C CZ . PHE A 1 769 ? 58.460 120.099 20.934 1.00 18.52 ? 769 PHE A CZ 1 ATOM 6202 N N . TRP A 1 770 ? 62.439 121.824 22.909 1.00 19.00 ? 770 TRP A N 1 ATOM 6203 C CA . TRP A 1 770 ? 61.935 122.279 24.202 1.00 19.79 ? 770 TRP A CA 1 ATOM 6204 C C . TRP A 1 770 ? 60.612 122.999 24.029 1.00 19.66 ? 770 TRP A C 1 ATOM 6205 O O . TRP A 1 770 ? 60.508 123.900 23.223 1.00 20.29 ? 770 TRP A O 1 ATOM 6206 C CB . TRP A 1 770 ? 62.957 123.176 24.929 1.00 20.26 ? 770 TRP A CB 1 ATOM 6207 C CG . TRP A 1 770 ? 62.676 123.269 26.408 1.00 22.57 ? 770 TRP A CG 1 ATOM 6208 C CD1 . TRP A 1 770 ? 62.088 124.314 27.057 1.00 22.12 ? 770 TRP A CD1 1 ATOM 6209 C CD2 . TRP A 1 770 ? 62.931 122.263 27.407 1.00 23.18 ? 770 TRP A CD2 1 ATOM 6210 N NE1 . TRP A 1 770 ? 61.978 124.027 28.396 1.00 23.80 ? 770 TRP A NE1 1 ATOM 6211 C CE2 . TRP A 1 770 ? 62.471 122.774 28.639 1.00 22.06 ? 770 TRP A CE2 1 ATOM 6212 C CE3 . TRP A 1 770 ? 63.493 120.970 27.376 1.00 25.35 ? 770 TRP A CE3 1 ATOM 6213 C CZ2 . TRP A 1 770 ? 62.575 122.053 29.852 1.00 21.96 ? 770 TRP A CZ2 1 ATOM 6214 C CZ3 . TRP A 1 770 ? 63.592 120.242 28.582 1.00 23.18 ? 770 TRP A CZ3 1 ATOM 6215 C CH2 . TRP A 1 770 ? 63.142 120.795 29.808 1.00 21.69 ? 770 TRP A CH2 1 ATOM 6216 N N . ASP A 1 771 ? 59.591 122.555 24.748 1.00 19.90 ? 771 ASP A N 1 ATOM 6217 C CA . ASP A 1 771 ? 58.327 123.272 24.749 1.00 20.48 ? 771 ASP A CA 1 ATOM 6218 C C . ASP A 1 771 ? 57.847 123.253 26.188 1.00 20.65 ? 771 ASP A C 1 ATOM 6219 O O . ASP A 1 771 ? 58.634 122.945 27.082 1.00 20.17 ? 771 ASP A O 1 ATOM 6220 C CB . ASP A 1 771 ? 57.352 122.667 23.711 1.00 19.65 ? 771 ASP A CB 1 ATOM 6221 C CG . ASP A 1 771 ? 56.820 121.290 24.103 1.00 20.21 ? 771 ASP A CG 1 ATOM 6222 O OD1 . ASP A 1 771 ? 57.302 120.701 25.084 1.00 20.49 ? 771 ASP A OD1 1 ATOM 6223 O OD2 . ASP A 1 771 ? 55.890 120.794 23.421 1.00 17.98 ? 771 ASP A OD2 1 ATOM 6224 N N . ASP A 1 772 ? 56.575 123.570 26.419 1.00 21.79 ? 772 ASP A N 1 ATOM 6225 C CA . ASP A 1 772 ? 56.024 123.597 27.765 1.00 21.98 ? 772 ASP A CA 1 ATOM 6226 C C . ASP A 1 772 ? 55.757 122.209 28.393 1.00 21.98 ? 772 ASP A C 1 ATOM 6227 O O . ASP A 1 772 ? 55.442 122.108 29.576 1.00 21.99 ? 772 ASP A O 1 ATOM 6228 C CB . ASP A 1 772 ? 54.803 124.566 27.840 1.00 21.78 ? 772 ASP A CB 1 ATOM 6229 C CG . ASP A 1 772 ? 53.511 123.960 27.299 1.00 24.67 ? 772 ASP A CG 1 ATOM 6230 O OD1 . ASP A 1 772 ? 53.480 122.762 26.914 1.00 24.33 ? 772 ASP A OD1 1 ATOM 6231 O OD2 . ASP A 1 772 ? 52.489 124.689 27.280 1.00 27.10 ? 772 ASP A OD2 1 ATOM 6232 N N . GLY A 1 773 ? 55.926 121.134 27.615 1.00 22.03 ? 773 GLY A N 1 ATOM 6233 C CA . GLY A 1 773 ? 55.889 119.771 28.161 1.00 21.47 ? 773 GLY A CA 1 ATOM 6234 C C . GLY A 1 773 ? 54.514 119.161 28.324 1.00 22.00 ? 773 GLY A C 1 ATOM 6235 O O . GLY A 1 773 ? 54.378 118.002 28.745 1.00 20.62 ? 773 GLY A O 1 ATOM 6236 N N . GLU A 1 774 ? 53.483 119.937 28.000 1.00 22.72 ? 774 GLU A N 1 ATOM 6237 C CA . GLU A 1 774 ? 52.120 119.476 28.234 1.00 24.02 ? 774 GLU A CA 1 ATOM 6238 C C . GLU A 1 774 ? 51.050 120.003 27.292 1.00 24.24 ? 774 GLU A C 1 ATOM 6239 O O . GLU A 1 774 ? 50.015 119.352 27.151 1.00 24.67 ? 774 GLU A O 1 ATOM 6240 C CB . GLU A 1 774 ? 51.723 119.736 29.679 1.00 24.99 ? 774 GLU A CB 1 ATOM 6241 C CG . GLU A 1 774 ? 51.745 121.186 30.057 1.00 27.55 ? 774 GLU A CG 1 ATOM 6242 C CD . GLU A 1 774 ? 51.241 121.406 31.474 1.00 34.36 ? 774 GLU A CD 1 ATOM 6243 O OE1 . GLU A 1 774 ? 51.979 120.998 32.402 1.00 35.13 ? 774 GLU A OE1 1 ATOM 6244 O OE2 . GLU A 1 774 ? 50.115 121.974 31.650 1.00 36.00 ? 774 GLU A OE2 1 ATOM 6245 N N . THR A 1 775 ? 51.261 121.147 26.633 1.00 24.05 ? 775 THR A N 1 ATOM 6246 C CA . THR A 1 775 ? 50.200 121.627 25.719 1.00 23.63 ? 775 THR A CA 1 ATOM 6247 C C . THR A 1 775 ? 50.034 120.740 24.473 1.00 23.65 ? 775 THR A C 1 ATOM 6248 O O . THR A 1 775 ? 51.040 120.360 23.814 1.00 21.83 ? 775 THR A O 1 ATOM 6249 C CB . THR A 1 775 ? 50.388 123.099 25.336 1.00 24.50 ? 775 THR A CB 1 ATOM 6250 O OG1 . THR A 1 775 ? 50.499 123.878 26.533 1.00 22.98 ? 775 THR A OG1 1 ATOM 6251 C CG2 . THR A 1 775 ? 49.186 123.632 24.479 1.00 24.52 ? 775 THR A CG2 1 ATOM 6252 N N . LYS A 1 776 ? 48.773 120.417 24.142 1.00 23.34 ? 776 LYS A N 1 ATOM 6253 C CA . LYS A 1 776 ? 48.493 119.625 22.959 1.00 24.84 ? 776 LYS A CA 1 ATOM 6254 C C . LYS A 1 776 ? 48.842 120.423 21.712 1.00 24.90 ? 776 LYS A C 1 ATOM 6255 O O . LYS A 1 776 ? 48.475 121.591 21.604 1.00 24.47 ? 776 LYS A O 1 ATOM 6256 C CB . LYS A 1 776 ? 47.026 119.161 22.906 1.00 24.60 ? 776 LYS A CB 1 ATOM 6257 C CG . LYS A 1 776 ? 46.757 118.033 21.901 1.00 26.56 ? 776 LYS A CG 1 ATOM 6258 C CD . LYS A 1 776 ? 45.354 117.432 22.024 1.00 27.27 ? 776 LYS A CD 1 ATOM 6259 C CE . LYS A 1 776 ? 45.304 116.178 22.931 1.00 31.49 ? 776 LYS A CE 1 ATOM 6260 N NZ . LYS A 1 776 ? 43.941 115.465 22.947 1.00 32.24 ? 776 LYS A NZ 1 ATOM 6261 N N . ASP A 1 777 ? 49.544 119.777 20.778 1.00 25.70 ? 777 ASP A N 1 ATOM 6262 C CA . ASP A 1 777 ? 49.827 120.334 19.436 1.00 26.89 ? 777 ASP A CA 1 ATOM 6263 C C . ASP A 1 777 ? 50.704 121.595 19.433 1.00 26.77 ? 777 ASP A C 1 ATOM 6264 O O . ASP A 1 777 ? 50.562 122.461 18.563 1.00 26.25 ? 777 ASP A O 1 ATOM 6265 C CB . ASP A 1 777 ? 48.541 120.564 18.638 1.00 27.11 ? 777 ASP A CB 1 ATOM 6266 C CG . ASP A 1 777 ? 47.947 119.272 18.121 1.00 31.90 ? 777 ASP A CG 1 ATOM 6267 O OD1 . ASP A 1 777 ? 48.751 118.384 17.713 1.00 36.08 ? 777 ASP A OD1 1 ATOM 6268 O OD2 . ASP A 1 777 ? 46.695 119.133 18.124 1.00 33.50 ? 777 ASP A OD2 1 ATOM 6269 N N . THR A 1 778 ? 51.634 121.682 20.388 1.00 25.97 ? 778 THR A N 1 ATOM 6270 C CA . THR A 1 778 ? 52.682 122.710 20.305 1.00 25.23 ? 778 THR A CA 1 ATOM 6271 C C . THR A 1 778 ? 53.472 122.635 18.997 1.00 25.06 ? 778 THR A C 1 ATOM 6272 O O . THR A 1 778 ? 53.965 123.648 18.520 1.00 26.11 ? 778 THR A O 1 ATOM 6273 C CB . THR A 1 778 ? 53.650 122.625 21.491 1.00 25.22 ? 778 THR A CB 1 ATOM 6274 O OG1 . THR A 1 778 ? 54.170 121.287 21.603 1.00 26.82 ? 778 THR A OG1 1 ATOM 6275 C CG2 . THR A 1 778 ? 52.948 123.003 22.757 1.00 23.42 ? 778 THR A CG2 1 ATOM 6276 N N . VAL A 1 779 ? 53.621 121.443 18.418 1.00 24.96 ? 779 VAL A N 1 ATOM 6277 C CA . VAL A 1 779 ? 54.425 121.280 17.180 1.00 24.59 ? 779 VAL A CA 1 ATOM 6278 C C . VAL A 1 779 ? 53.635 121.753 15.949 1.00 25.62 ? 779 VAL A C 1 ATOM 6279 O O . VAL A 1 779 ? 54.152 122.530 15.148 1.00 25.40 ? 779 VAL A O 1 ATOM 6280 C CB . VAL A 1 779 ? 54.977 119.849 17.011 1.00 24.33 ? 779 VAL A CB 1 ATOM 6281 C CG1 . VAL A 1 779 ? 55.564 119.637 15.640 1.00 23.46 ? 779 VAL A CG1 1 ATOM 6282 C CG2 . VAL A 1 779 ? 56.018 119.527 18.105 1.00 23.56 ? 779 VAL A CG2 1 ATOM 6283 N N . ALA A 1 780 ? 52.389 121.293 15.810 1.00 25.96 ? 780 ALA A N 1 ATOM 6284 C CA . ALA A 1 780 ? 51.531 121.729 14.719 1.00 27.34 ? 780 ALA A CA 1 ATOM 6285 C C . ALA A 1 780 ? 51.323 123.258 14.785 1.00 28.22 ? 780 ALA A C 1 ATOM 6286 O O . ALA A 1 780 ? 51.384 123.943 13.761 1.00 29.02 ? 780 ALA A O 1 ATOM 6287 C CB . ALA A 1 780 ? 50.180 120.982 14.737 1.00 27.42 ? 780 ALA A CB 1 ATOM 6288 N N . ASN A 1 781 ? 51.146 123.804 15.984 1.00 28.40 ? 781 ASN A N 1 ATOM 6289 C CA . ASN A 1 781 ? 51.006 125.262 16.120 1.00 28.40 ? 781 ASN A CA 1 ATOM 6290 C C . ASN A 1 781 ? 52.321 126.032 16.279 1.00 28.46 ? 781 ASN A C 1 ATOM 6291 O O . ASN A 1 781 ? 52.314 127.240 16.538 1.00 28.51 ? 781 ASN A O 1 ATOM 6292 C CB . ASN A 1 781 ? 50.025 125.604 17.248 1.00 28.63 ? 781 ASN A CB 1 ATOM 6293 C CG . ASN A 1 781 ? 48.686 124.942 17.054 1.00 28.25 ? 781 ASN A CG 1 ATOM 6294 O OD1 . ASN A 1 781 ? 48.111 124.419 17.991 1.00 32.49 ? 781 ASN A OD1 1 ATOM 6295 N ND2 . ASN A 1 781 ? 48.197 124.934 15.828 1.00 27.94 ? 781 ASN A ND2 1 ATOM 6296 N N . LYS A 1 782 ? 53.445 125.326 16.153 1.00 28.51 ? 782 LYS A N 1 ATOM 6297 C CA . LYS A 1 782 ? 54.771 125.953 16.172 1.00 28.29 ? 782 LYS A CA 1 ATOM 6298 C C . LYS A 1 782 ? 55.103 126.830 17.404 1.00 27.47 ? 782 LYS A C 1 ATOM 6299 O O . LYS A 1 782 ? 55.663 127.907 17.272 1.00 28.30 ? 782 LYS A O 1 ATOM 6300 C CB . LYS A 1 782 ? 55.009 126.703 14.851 1.00 29.60 ? 782 LYS A CB 1 ATOM 6301 C CG . LYS A 1 782 ? 54.955 125.786 13.630 1.00 33.72 ? 782 LYS A CG 1 ATOM 6302 C CD . LYS A 1 782 ? 56.065 126.107 12.627 1.00 41.35 ? 782 LYS A CD 1 ATOM 6303 C CE . LYS A 1 782 ? 56.165 125.042 11.519 1.00 42.81 ? 782 LYS A CE 1 ATOM 6304 N NZ . LYS A 1 782 ? 57.030 123.850 11.920 1.00 44.76 ? 782 LYS A NZ 1 ATOM 6305 N N . VAL A 1 783 ? 54.791 126.346 18.604 1.00 26.16 ? 783 VAL A N 1 ATOM 6306 C CA . VAL A 1 783 ? 55.185 127.012 19.844 1.00 25.25 ? 783 VAL A CA 1 ATOM 6307 C C . VAL A 1 783 ? 56.239 126.151 20.521 1.00 23.73 ? 783 VAL A C 1 ATOM 6308 O O . VAL A 1 783 ? 55.939 125.387 21.456 1.00 23.60 ? 783 VAL A O 1 ATOM 6309 C CB . VAL A 1 783 ? 53.964 127.286 20.791 1.00 25.01 ? 783 VAL A CB 1 ATOM 6310 C CG1 . VAL A 1 783 ? 54.368 128.192 21.969 1.00 24.63 ? 783 VAL A CG1 1 ATOM 6311 C CG2 . VAL A 1 783 ? 52.835 127.927 20.004 1.00 27.93 ? 783 VAL A CG2 1 ATOM 6312 N N . TYR A 1 784 ? 57.466 126.234 20.007 1.00 22.92 ? 784 TYR A N 1 ATOM 6313 C CA . TYR A 1 784 ? 58.566 125.447 20.559 1.00 22.70 ? 784 TYR A CA 1 ATOM 6314 C C . TYR A 1 784 ? 59.946 126.018 20.268 1.00 22.75 ? 784 TYR A C 1 ATOM 6315 O O . TYR A 1 784 ? 60.097 126.892 19.410 1.00 23.38 ? 784 TYR A O 1 ATOM 6316 C CB . TYR A 1 784 ? 58.474 123.979 20.123 1.00 22.23 ? 784 TYR A CB 1 ATOM 6317 C CG . TYR A 1 784 ? 58.658 123.677 18.637 1.00 22.68 ? 784 TYR A CG 1 ATOM 6318 C CD1 . TYR A 1 784 ? 59.926 123.382 18.111 1.00 23.23 ? 784 TYR A CD1 1 ATOM 6319 C CD2 . TYR A 1 784 ? 57.576 123.590 17.793 1.00 22.11 ? 784 TYR A CD2 1 ATOM 6320 C CE1 . TYR A 1 784 ? 60.088 123.063 16.766 1.00 23.34 ? 784 TYR A CE1 1 ATOM 6321 C CE2 . TYR A 1 784 ? 57.718 123.272 16.445 1.00 23.33 ? 784 TYR A CE2 1 ATOM 6322 C CZ . TYR A 1 784 ? 58.967 123.025 15.937 1.00 24.84 ? 784 TYR A CZ 1 ATOM 6323 O OH . TYR A 1 784 ? 59.102 122.702 14.614 1.00 24.28 ? 784 TYR A OH 1 ATOM 6324 N N . LEU A 1 785 ? 60.936 125.532 21.012 1.00 21.87 ? 785 LEU A N 1 ATOM 6325 C CA . LEU A 1 785 ? 62.329 125.821 20.746 1.00 21.99 ? 785 LEU A CA 1 ATOM 6326 C C . LEU A 1 785 ? 62.977 124.581 20.152 1.00 22.17 ? 785 LEU A C 1 ATOM 6327 O O . LEU A 1 785 ? 62.734 123.474 20.612 1.00 21.61 ? 785 LEU A O 1 ATOM 6328 C CB . LEU A 1 785 ? 63.061 126.235 22.024 1.00 21.38 ? 785 LEU A CB 1 ATOM 6329 C CG . LEU A 1 785 ? 64.593 126.324 21.892 1.00 22.32 ? 785 LEU A CG 1 ATOM 6330 C CD1 . LEU A 1 785 ? 65.025 127.494 21.018 1.00 22.56 ? 785 LEU A CD1 1 ATOM 6331 C CD2 . LEU A 1 785 ? 65.217 126.436 23.258 1.00 21.27 ? 785 LEU A CD2 1 ATOM 6332 N N . LEU A 1 786 ? 63.795 124.774 19.119 1.00 23.70 ? 786 LEU A N 1 ATOM 6333 C CA . LEU A 1 786 ? 64.642 123.703 18.590 1.00 24.42 ? 786 LEU A CA 1 ATOM 6334 C C . LEU A 1 786 ? 66.013 124.262 18.325 1.00 25.34 ? 786 LEU A C 1 ATOM 6335 O O . LEU A 1 786 ? 66.165 125.208 17.560 1.00 25.32 ? 786 LEU A O 1 ATOM 6336 C CB . LEU A 1 786 ? 64.046 123.059 17.313 1.00 23.23 ? 786 LEU A CB 1 ATOM 6337 C CG . LEU A 1 786 ? 64.829 121.891 16.669 1.00 23.81 ? 786 LEU A CG 1 ATOM 6338 C CD1 . LEU A 1 786 ? 64.941 120.635 17.584 1.00 21.81 ? 786 LEU A CD1 1 ATOM 6339 C CD2 . LEU A 1 786 ? 64.191 121.507 15.322 1.00 23.38 ? 786 LEU A CD2 1 ATOM 6340 N N . CYS A 1 787 ? 67.012 123.685 18.974 1.00 26.50 ? 787 CYS A N 1 ATOM 6341 C CA . CYS A 1 787 ? 68.373 124.050 18.689 1.00 28.90 ? 787 CYS A CA 1 ATOM 6342 C C . CYS A 1 787 ? 69.268 122.885 18.265 1.00 28.44 ? 787 CYS A C 1 ATOM 6343 O O . CYS A 1 787 ? 68.930 121.709 18.473 1.00 27.65 ? 787 CYS A O 1 ATOM 6344 C CB . CYS A 1 787 ? 68.983 124.874 19.821 1.00 29.80 ? 787 CYS A CB 1 ATOM 6345 S SG . CYS A 1 787 ? 68.990 124.153 21.419 1.00 36.92 ? 787 CYS A SG 1 ATOM 6346 N N . GLU A 1 788 ? 70.368 123.237 17.603 1.00 27.88 ? 788 GLU A N 1 ATOM 6347 C CA . GLU A 1 788 ? 71.368 122.283 17.141 1.00 28.39 ? 788 GLU A CA 1 ATOM 6348 C C . GLU A 1 788 ? 72.690 122.605 17.821 1.00 27.06 ? 788 GLU A C 1 ATOM 6349 O O . GLU A 1 788 ? 73.024 123.768 18.028 1.00 27.32 ? 788 GLU A O 1 ATOM 6350 C CB . GLU A 1 788 ? 71.550 122.398 15.635 1.00 29.44 ? 788 GLU A CB 1 ATOM 6351 C CG . GLU A 1 788 ? 70.255 122.732 14.862 1.00 36.21 ? 788 GLU A CG 1 ATOM 6352 C CD . GLU A 1 788 ? 70.431 123.877 13.812 1.00 44.67 ? 788 GLU A CD 1 ATOM 6353 O OE1 . GLU A 1 788 ? 71.317 123.769 12.907 1.00 45.98 ? 788 GLU A OE1 1 ATOM 6354 O OE2 . GLU A 1 788 ? 69.658 124.886 13.892 1.00 46.41 ? 788 GLU A OE2 1 ATOM 6355 N N . PHE A 1 789 ? 73.415 121.564 18.185 1.00 25.46 ? 789 PHE A N 1 ATOM 6356 C CA . PHE A 1 789 ? 74.752 121.662 18.705 1.00 24.21 ? 789 PHE A CA 1 ATOM 6357 C C . PHE A 1 789 ? 75.617 121.011 17.642 1.00 24.96 ? 789 PHE A C 1 ATOM 6358 O O . PHE A 1 789 ? 75.275 119.942 17.127 1.00 24.57 ? 789 PHE A O 1 ATOM 6359 C CB . PHE A 1 789 ? 74.863 120.889 20.028 1.00 23.84 ? 789 PHE A CB 1 ATOM 6360 C CG . PHE A 1 789 ? 73.709 121.122 20.965 1.00 24.31 ? 789 PHE A CG 1 ATOM 6361 C CD1 . PHE A 1 789 ? 73.551 122.361 21.619 1.00 22.15 ? 789 PHE A CD1 1 ATOM 6362 C CD2 . PHE A 1 789 ? 72.763 120.107 21.202 1.00 25.86 ? 789 PHE A CD2 1 ATOM 6363 C CE1 . PHE A 1 789 ? 72.469 122.589 22.498 1.00 23.13 ? 789 PHE A CE1 1 ATOM 6364 C CE2 . PHE A 1 789 ? 71.656 120.336 22.063 1.00 23.62 ? 789 PHE A CE2 1 ATOM 6365 C CZ . PHE A 1 789 ? 71.515 121.572 22.702 1.00 22.73 ? 789 PHE A CZ 1 ATOM 6366 N N . SER A 1 790 ? 76.701 121.669 17.261 1.00 25.20 ? 790 SER A N 1 ATOM 6367 C CA . SER A 1 790 ? 77.713 121.026 16.458 1.00 27.46 ? 790 SER A CA 1 ATOM 6368 C C . SER A 1 790 ? 79.087 121.393 16.955 1.00 27.89 ? 790 SER A C 1 ATOM 6369 O O . SER A 1 790 ? 79.358 122.541 17.242 1.00 27.37 ? 790 SER A O 1 ATOM 6370 C CB . SER A 1 790 ? 77.569 121.350 14.968 1.00 27.62 ? 790 SER A CB 1 ATOM 6371 O OG . SER A 1 790 ? 77.598 122.744 14.738 1.00 33.76 ? 790 SER A OG 1 ATOM 6372 N N . VAL A 1 791 ? 79.930 120.378 17.051 1.00 28.95 ? 791 VAL A N 1 ATOM 6373 C CA . VAL A 1 791 ? 81.313 120.492 17.450 1.00 30.72 ? 791 VAL A CA 1 ATOM 6374 C C . VAL A 1 791 ? 82.214 120.117 16.259 1.00 32.50 ? 791 VAL A C 1 ATOM 6375 O O . VAL A 1 791 ? 81.959 119.134 15.546 1.00 31.19 ? 791 VAL A O 1 ATOM 6376 C CB . VAL A 1 791 ? 81.627 119.574 18.664 1.00 30.64 ? 791 VAL A CB 1 ATOM 6377 C CG1 . VAL A 1 791 ? 83.115 119.594 18.995 1.00 31.74 ? 791 VAL A CG1 1 ATOM 6378 C CG2 . VAL A 1 791 ? 80.829 120.024 19.867 1.00 29.77 ? 791 VAL A CG2 1 ATOM 6379 N N . THR A 1 792 ? 83.195 120.982 16.011 1.00 34.27 ? 792 THR A N 1 ATOM 6380 C CA . THR A 1 792 ? 84.311 120.696 15.118 1.00 37.01 ? 792 THR A CA 1 ATOM 6381 C C . THR A 1 792 ? 85.554 120.839 15.976 1.00 38.20 ? 792 THR A C 1 ATOM 6382 O O . THR A 1 792 ? 85.453 121.054 17.203 1.00 38.40 ? 792 THR A O 1 ATOM 6383 C CB . THR A 1 792 ? 84.388 121.684 13.947 1.00 36.92 ? 792 THR A CB 1 ATOM 6384 O OG1 . THR A 1 792 ? 84.116 123.012 14.429 1.00 38.57 ? 792 THR A OG1 1 ATOM 6385 C CG2 . THR A 1 792 ? 83.360 121.315 12.896 1.00 37.26 ? 792 THR A CG2 1 ATOM 6386 N N . GLN A 1 793 ? 86.728 120.715 15.363 1.00 39.46 ? 793 GLN A N 1 ATOM 6387 C CA . GLN A 1 793 ? 87.939 120.896 16.143 1.00 40.31 ? 793 GLN A CA 1 ATOM 6388 C C . GLN A 1 793 ? 87.944 122.327 16.678 1.00 39.55 ? 793 GLN A C 1 ATOM 6389 O O . GLN A 1 793 ? 87.608 123.293 15.946 1.00 38.77 ? 793 GLN A O 1 ATOM 6390 C CB . GLN A 1 793 ? 89.200 120.478 15.363 1.00 40.71 ? 793 GLN A CB 1 ATOM 6391 C CG . GLN A 1 793 ? 89.259 118.930 15.159 1.00 41.57 ? 793 GLN A CG 1 ATOM 6392 C CD . GLN A 1 793 ? 90.454 118.437 14.312 1.00 42.25 ? 793 GLN A CD 1 ATOM 6393 O OE1 . GLN A 1 793 ? 91.013 119.204 13.515 1.00 44.57 ? 793 GLN A OE1 1 ATOM 6394 N NE2 . GLN A 1 793 ? 90.848 117.148 14.491 1.00 41.92 ? 793 GLN A NE2 1 ATOM 6395 N N . ASN A 1 794 ? 88.219 122.427 17.984 1.00 39.04 ? 794 ASN A N 1 ATOM 6396 C CA . ASN A 1 794 ? 88.359 123.716 18.683 1.00 39.03 ? 794 ASN A CA 1 ATOM 6397 C C . ASN A 1 794 ? 87.066 124.559 18.876 1.00 38.17 ? 794 ASN A C 1 ATOM 6398 O O . ASN A 1 794 ? 87.141 125.726 19.271 1.00 38.41 ? 794 ASN A O 1 ATOM 6399 C CB . ASN A 1 794 ? 89.443 124.599 17.999 1.00 39.72 ? 794 ASN A CB 1 ATOM 6400 C CG . ASN A 1 794 ? 90.784 123.894 17.862 1.00 40.98 ? 794 ASN A CG 1 ATOM 6401 O OD1 . ASN A 1 794 ? 91.480 123.664 18.842 1.00 44.02 ? 794 ASN A OD1 1 ATOM 6402 N ND2 . ASN A 1 794 ? 91.154 123.565 16.638 1.00 41.61 ? 794 ASN A ND2 1 ATOM 6403 N N . ARG A 1 795 ? 85.893 124.003 18.601 1.00 36.75 ? 795 ARG A N 1 ATOM 6404 C CA . ARG A 1 795 ? 84.715 124.849 18.521 1.00 36.32 ? 795 ARG A CA 1 ATOM 6405 C C . ARG A 1 795 ? 83.387 124.118 18.763 1.00 35.03 ? 795 ARG A C 1 ATOM 6406 O O . ARG A 1 795 ? 83.132 123.073 18.166 1.00 34.90 ? 795 ARG A O 1 ATOM 6407 C CB . ARG A 1 795 ? 84.712 125.514 17.147 1.00 36.87 ? 795 ARG A CB 1 ATOM 6408 C CG . ARG A 1 795 ? 83.675 126.585 16.905 1.00 40.54 ? 795 ARG A CG 1 ATOM 6409 C CD . ARG A 1 795 ? 83.558 126.804 15.406 1.00 48.32 ? 795 ARG A CD 1 ATOM 6410 N NE . ARG A 1 795 ? 82.906 128.072 15.091 1.00 55.34 ? 795 ARG A NE 1 ATOM 6411 C CZ . ARG A 1 795 ? 83.547 129.162 14.666 1.00 58.20 ? 795 ARG A CZ 1 ATOM 6412 N NH1 . ARG A 1 795 ? 84.870 129.143 14.494 1.00 59.47 ? 795 ARG A NH1 1 ATOM 6413 N NH2 . ARG A 1 795 ? 82.862 130.273 14.404 1.00 58.00 ? 795 ARG A NH2 1 ATOM 6414 N N . LEU A 1 796 ? 82.552 124.677 19.639 1.00 33.68 ? 796 LEU A N 1 ATOM 6415 C CA . LEU A 1 796 ? 81.151 124.269 19.761 1.00 32.43 ? 796 LEU A CA 1 ATOM 6416 C C . LEU A 1 796 ? 80.234 125.432 19.365 1.00 32.66 ? 796 LEU A C 1 ATOM 6417 O O . LEU A 1 796 ? 80.385 126.543 19.878 1.00 31.80 ? 796 LEU A O 1 ATOM 6418 C CB . LEU A 1 796 ? 80.816 123.812 21.200 1.00 32.25 ? 796 LEU A CB 1 ATOM 6419 C CG . LEU A 1 796 ? 79.340 123.810 21.646 1.00 31.26 ? 796 LEU A CG 1 ATOM 6420 C CD1 . LEU A 1 796 ? 78.527 122.648 21.040 1.00 25.96 ? 796 LEU A CD1 1 ATOM 6421 C CD2 . LEU A 1 796 ? 79.209 123.849 23.161 1.00 31.37 ? 796 LEU A CD2 1 ATOM 6422 N N . GLU A 1 797 ? 79.270 125.150 18.487 1.00 32.40 ? 797 GLU A N 1 ATOM 6423 C CA . GLU A 1 797 ? 78.222 126.096 18.103 1.00 33.65 ? 797 GLU A CA 1 ATOM 6424 C C . GLU A 1 797 ? 76.880 125.659 18.651 1.00 32.67 ? 797 GLU A C 1 ATOM 6425 O O . GLU A 1 797 ? 76.457 124.517 18.441 1.00 32.23 ? 797 GLU A O 1 ATOM 6426 C CB . GLU A 1 797 ? 78.090 126.186 16.574 1.00 34.33 ? 797 GLU A CB 1 ATOM 6427 C CG . GLU A 1 797 ? 79.152 126.988 15.889 1.00 41.64 ? 797 GLU A CG 1 ATOM 6428 C CD . GLU A 1 797 ? 79.221 126.698 14.385 1.00 51.34 ? 797 GLU A CD 1 ATOM 6429 O OE1 . GLU A 1 797 ? 78.212 126.933 13.650 1.00 53.94 ? 797 GLU A OE1 1 ATOM 6430 O OE2 . GLU A 1 797 ? 80.305 126.240 13.934 1.00 55.17 ? 797 GLU A OE2 1 ATOM 6431 N N . VAL A 1 798 ? 76.212 126.574 19.345 1.00 32.22 ? 798 VAL A N 1 ATOM 6432 C CA . VAL A 1 798 ? 74.817 126.409 19.694 1.00 31.95 ? 798 VAL A CA 1 ATOM 6433 C C . VAL A 1 798 ? 74.027 127.340 18.767 1.00 32.74 ? 798 VAL A C 1 ATOM 6434 O O . VAL A 1 798 ? 74.253 128.548 18.736 1.00 32.48 ? 798 VAL A O 1 ATOM 6435 C CB . VAL A 1 798 ? 74.511 126.695 21.209 1.00 31.70 ? 798 VAL A CB 1 ATOM 6436 C CG1 . VAL A 1 798 ? 73.033 126.434 21.514 1.00 31.52 ? 798 VAL A CG1 1 ATOM 6437 C CG2 . VAL A 1 798 ? 75.383 125.857 22.132 1.00 30.91 ? 798 VAL A CG2 1 ATOM 6438 N N . ASN A 1 799 ? 73.062 126.753 18.067 1.00 33.11 ? 799 ASN A N 1 ATOM 6439 C CA . ASN A 1 799 ? 72.418 127.313 16.916 1.00 34.15 ? 799 ASN A CA 1 ATOM 6440 C C . ASN A 1 799 ? 70.910 127.127 17.090 1.00 34.01 ? 799 ASN A C 1 ATOM 6441 O O . ASN A 1 799 ? 70.474 126.058 17.502 1.00 34.19 ? 799 ASN A O 1 ATOM 6442 C CB . ASN A 1 799 ? 72.881 126.472 15.739 1.00 34.75 ? 799 ASN A CB 1 ATOM 6443 C CG . ASN A 1 799 ? 72.984 127.244 14.477 1.00 38.94 ? 799 ASN A CG 1 ATOM 6444 O OD1 . ASN A 1 799 ? 72.037 127.947 14.078 1.00 43.99 ? 799 ASN A OD1 1 ATOM 6445 N ND2 . ASN A 1 799 ? 74.136 127.111 13.794 1.00 42.83 ? 799 ASN A ND2 1 ATOM 6446 N N . ILE A 1 800 ? 70.108 128.142 16.791 1.00 33.64 ? 800 ILE A N 1 ATOM 6447 C CA . ILE A 1 800 ? 68.661 128.050 17.046 1.00 34.14 ? 800 ILE A CA 1 ATOM 6448 C C . ILE A 1 800 ? 67.895 127.991 15.740 1.00 34.30 ? 800 ILE A C 1 ATOM 6449 O O . ILE A 1 800 ? 68.013 128.912 14.944 1.00 33.77 ? 800 ILE A O 1 ATOM 6450 C CB . ILE A 1 800 ? 68.095 129.282 17.854 1.00 34.08 ? 800 ILE A CB 1 ATOM 6451 C CG1 . ILE A 1 800 ? 68.897 129.589 19.123 1.00 34.58 ? 800 ILE A CG1 1 ATOM 6452 C CG2 . ILE A 1 800 ? 66.588 129.092 18.144 1.00 34.39 ? 800 ILE A CG2 1 ATOM 6453 C CD1 . ILE A 1 800 ? 69.082 128.431 20.094 1.00 35.75 ? 800 ILE A CD1 1 ATOM 6454 N N . SER A 1 801 ? 67.072 126.956 15.529 1.00 34.31 ? 801 SER A N 1 ATOM 6455 C CA . SER A 1 801 ? 66.316 126.889 14.285 1.00 34.84 ? 801 SER A CA 1 ATOM 6456 C C . SER A 1 801 ? 64.839 127.322 14.388 1.00 34.67 ? 801 SER A C 1 ATOM 6457 O O . SER A 1 801 ? 64.320 127.957 13.474 1.00 35.56 ? 801 SER A O 1 ATOM 6458 C CB . SER A 1 801 ? 66.471 125.533 13.597 1.00 34.72 ? 801 SER A CB 1 ATOM 6459 O OG . SER A 1 801 ? 65.676 124.560 14.235 1.00 37.41 ? 801 SER A OG 1 ATOM 6460 N N . GLN A 1 802 ? 64.163 126.943 15.467 1.00 33.44 ? 802 GLN A N 1 ATOM 6461 C CA . GLN A 1 802 ? 62.796 127.363 15.708 1.00 32.21 ? 802 GLN A CA 1 ATOM 6462 C C . GLN A 1 802 ? 62.870 127.966 17.079 1.00 31.55 ? 802 GLN A C 1 ATOM 6463 O O . GLN A 1 802 ? 63.523 127.413 17.952 1.00 31.60 ? 802 GLN A O 1 ATOM 6464 C CB . GLN A 1 802 ? 61.824 126.182 15.674 1.00 31.80 ? 802 GLN A CB 1 ATOM 6465 C CG . GLN A 1 802 ? 60.355 126.497 16.027 1.00 31.72 ? 802 GLN A CG 1 ATOM 6466 C CD . GLN A 1 802 ? 59.650 127.316 14.965 1.00 33.13 ? 802 GLN A CD 1 ATOM 6467 O OE1 . GLN A 1 802 ? 58.837 128.201 15.278 1.00 34.68 ? 802 GLN A OE1 1 ATOM 6468 N NE2 . GLN A 1 802 ? 59.952 127.038 13.706 1.00 32.17 ? 802 GLN A NE2 1 ATOM 6469 N N . SER A 1 803 ? 62.225 129.108 17.258 1.00 30.73 ? 803 SER A N 1 ATOM 6470 C CA . SER A 1 803 ? 62.355 129.846 18.497 1.00 30.98 ? 803 SER A CA 1 ATOM 6471 C C . SER A 1 803 ? 61.065 130.520 18.902 1.00 30.40 ? 803 SER A C 1 ATOM 6472 O O . SER A 1 803 ? 61.001 131.749 19.005 1.00 31.35 ? 803 SER A O 1 ATOM 6473 C CB . SER A 1 803 ? 63.426 130.925 18.364 1.00 31.01 ? 803 SER A CB 1 ATOM 6474 O OG . SER A 1 803 ? 63.548 131.542 19.627 1.00 32.24 ? 803 SER A OG 1 ATOM 6475 N N . THR A 1 804 ? 60.028 129.748 19.137 1.00 29.42 ? 804 THR A N 1 ATOM 6476 C CA . THR A 1 804 ? 58.772 130.374 19.508 1.00 28.14 ? 804 THR A CA 1 ATOM 6477 C C . THR A 1 804 ? 58.291 129.945 20.878 1.00 27.36 ? 804 THR A C 1 ATOM 6478 O O . THR A 1 804 ? 57.122 130.023 21.151 1.00 27.95 ? 804 THR A O 1 ATOM 6479 C CB . THR A 1 804 ? 57.695 130.202 18.439 1.00 28.58 ? 804 THR A CB 1 ATOM 6480 O OG1 . THR A 1 804 ? 57.614 128.820 18.056 1.00 30.02 ? 804 THR A OG1 1 ATOM 6481 C CG2 . THR A 1 804 ? 58.006 131.081 17.215 1.00 28.04 ? 804 THR A CG2 1 ATOM 6482 N N . TYR A 1 805 ? 59.207 129.507 21.730 1.00 26.20 ? 805 TYR A N 1 ATOM 6483 C CA . TYR A 1 805 ? 58.920 129.229 23.120 1.00 26.19 ? 805 TYR A CA 1 ATOM 6484 C C . TYR A 1 805 ? 60.120 129.607 23.946 1.00 27.14 ? 805 TYR A C 1 ATOM 6485 O O . TYR A 1 805 ? 61.211 129.109 23.723 1.00 26.78 ? 805 TYR A O 1 ATOM 6486 C CB . TYR A 1 805 ? 58.586 127.740 23.384 1.00 25.68 ? 805 TYR A CB 1 ATOM 6487 C CG . TYR A 1 805 ? 58.238 127.471 24.830 1.00 24.66 ? 805 TYR A CG 1 ATOM 6488 C CD1 . TYR A 1 805 ? 57.053 127.981 25.381 1.00 23.82 ? 805 TYR A CD1 1 ATOM 6489 C CD2 . TYR A 1 805 ? 59.106 126.759 25.665 1.00 25.13 ? 805 TYR A CD2 1 ATOM 6490 C CE1 . TYR A 1 805 ? 56.738 127.780 26.725 1.00 25.21 ? 805 TYR A CE1 1 ATOM 6491 C CE2 . TYR A 1 805 ? 58.795 126.545 27.019 1.00 26.00 ? 805 TYR A CE2 1 ATOM 6492 C CZ . TYR A 1 805 ? 57.599 127.057 27.530 1.00 23.97 ? 805 TYR A CZ 1 ATOM 6493 O OH . TYR A 1 805 ? 57.244 126.860 28.844 1.00 26.31 ? 805 TYR A OH 1 ATOM 6494 N N . LYS A 1 806 ? 59.910 130.495 24.909 1.00 28.28 ? 806 LYS A N 1 ATOM 6495 C CA . LYS A 1 806 ? 60.951 130.826 25.860 1.00 29.81 ? 806 LYS A CA 1 ATOM 6496 C C . LYS A 1 806 ? 60.463 130.363 27.217 1.00 29.52 ? 806 LYS A C 1 ATOM 6497 O O . LYS A 1 806 ? 59.472 130.897 27.727 1.00 30.10 ? 806 LYS A O 1 ATOM 6498 C CB . LYS A 1 806 ? 61.242 132.337 25.845 1.00 31.08 ? 806 LYS A CB 1 ATOM 6499 C CG . LYS A 1 806 ? 62.361 132.744 26.828 1.00 33.06 ? 806 LYS A CG 1 ATOM 6500 C CD . LYS A 1 806 ? 63.622 133.262 26.150 1.00 37.15 ? 806 LYS A CD 1 ATOM 6501 C CE . LYS A 1 806 ? 64.554 133.915 27.206 1.00 37.40 ? 806 LYS A CE 1 ATOM 6502 N NZ . LYS A 1 806 ? 65.985 134.030 26.755 1.00 40.79 ? 806 LYS A NZ 1 ATOM 6503 N N . ASP A 1 807 ? 61.126 129.350 27.779 1.00 29.08 ? 807 ASP A N 1 ATOM 6504 C CA . ASP A 1 807 ? 60.758 128.780 29.074 1.00 29.48 ? 807 ASP A CA 1 ATOM 6505 C C . ASP A 1 807 ? 60.889 129.885 30.150 1.00 30.26 ? 807 ASP A C 1 ATOM 6506 O O . ASP A 1 807 ? 61.927 130.515 30.234 1.00 30.04 ? 807 ASP A O 1 ATOM 6507 C CB . ASP A 1 807 ? 61.644 127.550 29.394 1.00 29.29 ? 807 ASP A CB 1 ATOM 6508 C CG . ASP A 1 807 ? 61.179 126.789 30.637 1.00 30.01 ? 807 ASP A CG 1 ATOM 6509 O OD1 . ASP A 1 807 ? 61.200 127.384 31.730 1.00 35.63 ? 807 ASP A OD1 1 ATOM 6510 O OD2 . ASP A 1 807 ? 60.777 125.610 30.549 1.00 27.02 ? 807 ASP A OD2 1 ATOM 6511 N N . PRO A 1 808 ? 59.815 130.154 30.935 1.00 30.81 ? 808 PRO A N 1 ATOM 6512 C CA . PRO A 1 808 ? 59.838 131.245 31.943 1.00 30.71 ? 808 PRO A CA 1 ATOM 6513 C C . PRO A 1 808 ? 60.776 131.019 33.124 1.00 30.57 ? 808 PRO A C 1 ATOM 6514 O O . PRO A 1 808 ? 61.048 131.956 33.890 1.00 30.58 ? 808 PRO A O 1 ATOM 6515 C CB . PRO A 1 808 ? 58.381 131.296 32.440 1.00 31.39 ? 808 PRO A CB 1 ATOM 6516 C CG . PRO A 1 808 ? 57.838 129.924 32.167 1.00 30.90 ? 808 PRO A CG 1 ATOM 6517 C CD . PRO A 1 808 ? 58.490 129.505 30.869 1.00 30.67 ? 808 PRO A CD 1 ATOM 6518 N N . ASN A 1 809 ? 61.273 129.793 33.266 1.00 30.30 ? 809 ASN A N 1 ATOM 6519 C CA . ASN A 1 809 ? 62.129 129.431 34.391 1.00 30.56 ? 809 ASN A CA 1 ATOM 6520 C C . ASN A 1 809 ? 63.596 129.788 34.211 1.00 30.80 ? 809 ASN A C 1 ATOM 6521 O O . ASN A 1 809 ? 64.415 129.337 34.996 1.00 31.91 ? 809 ASN A O 1 ATOM 6522 C CB . ASN A 1 809 ? 61.992 127.945 34.756 1.00 29.65 ? 809 ASN A CB 1 ATOM 6523 C CG . ASN A 1 809 ? 60.600 127.592 35.259 1.00 31.26 ? 809 ASN A CG 1 ATOM 6524 O OD1 . ASN A 1 809 ? 59.989 126.622 34.804 1.00 31.26 ? 809 ASN A OD1 1 ATOM 6525 N ND2 . ASN A 1 809 ? 60.088 128.383 36.196 1.00 29.96 ? 809 ASN A ND2 1 ATOM 6526 N N . ASN A 1 810 ? 63.943 130.578 33.199 1.00 31.03 ? 810 ASN A N 1 ATOM 6527 C CA . ASN A 1 810 ? 65.338 131.076 33.084 1.00 31.98 ? 810 ASN A CA 1 ATOM 6528 C C . ASN A 1 810 ? 66.374 129.930 33.036 1.00 30.88 ? 810 ASN A C 1 ATOM 6529 O O . ASN A 1 810 ? 67.310 129.886 33.852 1.00 31.40 ? 810 ASN A O 1 ATOM 6530 C CB . ASN A 1 810 ? 65.647 132.043 34.267 1.00 33.08 ? 810 ASN A CB 1 ATOM 6531 C CG . ASN A 1 810 ? 66.861 132.965 34.013 1.00 35.84 ? 810 ASN A CG 1 ATOM 6532 O OD1 . ASN A 1 810 ? 67.047 133.527 32.914 1.00 38.56 ? 810 ASN A OD1 1 ATOM 6533 N ND2 . ASN A 1 810 ? 67.686 133.127 35.049 1.00 40.81 ? 810 ASN A ND2 1 ATOM 6534 N N . LEU A 1 811 ? 66.189 128.990 32.103 1.00 29.24 ? 811 LEU A N 1 ATOM 6535 C CA . LEU A 1 811 ? 67.043 127.794 32.039 1.00 27.83 ? 811 LEU A CA 1 ATOM 6536 C C . LEU A 1 811 ? 68.370 128.059 31.306 1.00 26.58 ? 811 LEU A C 1 ATOM 6537 O O . LEU A 1 811 ? 68.419 128.893 30.396 1.00 25.77 ? 811 LEU A O 1 ATOM 6538 C CB . LEU A 1 811 ? 66.305 126.639 31.354 1.00 27.54 ? 811 LEU A CB 1 ATOM 6539 C CG . LEU A 1 811 ? 64.968 126.158 31.948 1.00 28.53 ? 811 LEU A CG 1 ATOM 6540 C CD1 . LEU A 1 811 ? 64.503 124.916 31.215 1.00 27.70 ? 811 LEU A CD1 1 ATOM 6541 C CD2 . LEU A 1 811 ? 65.103 125.890 33.431 1.00 26.35 ? 811 LEU A CD2 1 ATOM 6542 N N . ALA A 1 812 ? 69.415 127.308 31.669 1.00 25.06 ? 812 ALA A N 1 ATOM 6543 C CA . ALA A 1 812 ? 70.723 127.511 31.072 1.00 25.21 ? 812 ALA A CA 1 ATOM 6544 C C . ALA A 1 812 ? 71.598 126.274 31.162 1.00 24.39 ? 812 ALA A C 1 ATOM 6545 O O . ALA A 1 812 ? 71.506 125.512 32.116 1.00 23.74 ? 812 ALA A O 1 ATOM 6546 C CB . ALA A 1 812 ? 71.433 128.707 31.765 1.00 24.97 ? 812 ALA A CB 1 ATOM 6547 N N . PHE A 1 813 ? 72.454 126.082 30.167 1.00 24.68 ? 813 PHE A N 1 ATOM 6548 C CA . PHE A 1 813 ? 73.488 125.072 30.252 1.00 25.35 ? 813 PHE A CA 1 ATOM 6549 C C . PHE A 1 813 ? 74.583 125.572 31.215 1.00 26.29 ? 813 PHE A C 1 ATOM 6550 O O . PHE A 1 813 ? 75.107 126.658 31.028 1.00 27.06 ? 813 PHE A O 1 ATOM 6551 C CB . PHE A 1 813 ? 74.070 124.748 28.873 1.00 24.78 ? 813 PHE A CB 1 ATOM 6552 C CG . PHE A 1 813 ? 73.055 124.235 27.879 1.00 25.88 ? 813 PHE A CG 1 ATOM 6553 C CD1 . PHE A 1 813 ? 72.768 122.871 27.787 1.00 25.06 ? 813 PHE A CD1 1 ATOM 6554 C CD2 . PHE A 1 813 ? 72.373 125.118 27.037 1.00 26.55 ? 813 PHE A CD2 1 ATOM 6555 C CE1 . PHE A 1 813 ? 71.810 122.410 26.877 1.00 24.35 ? 813 PHE A CE1 1 ATOM 6556 C CE2 . PHE A 1 813 ? 71.432 124.651 26.120 1.00 26.49 ? 813 PHE A CE2 1 ATOM 6557 C CZ . PHE A 1 813 ? 71.147 123.285 26.049 1.00 23.46 ? 813 PHE A CZ 1 ATOM 6558 N N . ASN A 1 814 ? 74.900 124.794 32.248 1.00 27.31 ? 814 ASN A N 1 ATOM 6559 C CA . ASN A 1 814 ? 75.921 125.167 33.238 1.00 28.56 ? 814 ASN A CA 1 ATOM 6560 C C . ASN A 1 814 ? 77.083 124.190 33.283 1.00 28.67 ? 814 ASN A C 1 ATOM 6561 O O . ASN A 1 814 ? 78.014 124.393 34.050 1.00 28.76 ? 814 ASN A O 1 ATOM 6562 C CB . ASN A 1 814 ? 75.322 125.403 34.656 1.00 29.05 ? 814 ASN A CB 1 ATOM 6563 C CG . ASN A 1 814 ? 74.977 124.095 35.401 1.00 33.46 ? 814 ASN A CG 1 ATOM 6564 O OD1 . ASN A 1 814 ? 74.829 123.018 34.793 1.00 37.08 ? 814 ASN A OD1 1 ATOM 6565 N ND2 . ASN A 1 814 ? 74.846 124.186 36.734 1.00 34.11 ? 814 ASN A ND2 1 ATOM 6566 N N . GLU A 1 815 ? 77.039 123.142 32.443 1.00 28.64 ? 815 GLU A N 1 ATOM 6567 C CA . GLU A 1 815 ? 78.113 122.130 32.400 1.00 28.68 ? 815 GLU A CA 1 ATOM 6568 C C . GLU A 1 815 ? 78.153 121.465 31.039 1.00 27.35 ? 815 GLU A C 1 ATOM 6569 O O . GLU A 1 815 ? 77.117 121.169 30.458 1.00 26.40 ? 815 GLU A O 1 ATOM 6570 C CB . GLU A 1 815 ? 77.948 121.049 33.483 1.00 28.79 ? 815 GLU A CB 1 ATOM 6571 C CG . GLU A 1 815 ? 79.161 120.117 33.540 1.00 31.59 ? 815 GLU A CG 1 ATOM 6572 C CD . GLU A 1 815 ? 79.054 118.909 34.486 1.00 33.56 ? 815 GLU A CD 1 ATOM 6573 O OE1 . GLU A 1 815 ? 79.255 119.050 35.728 1.00 39.57 ? 815 GLU A OE1 1 ATOM 6574 O OE2 . GLU A 1 815 ? 78.876 117.773 33.955 1.00 42.47 ? 815 GLU A OE2 1 ATOM 6575 N N . ILE A 1 816 ? 79.362 121.207 30.553 1.00 26.50 ? 816 ILE A N 1 ATOM 6576 C CA . ILE A 1 816 ? 79.603 120.507 29.286 1.00 25.47 ? 816 ILE A CA 1 ATOM 6577 C C . ILE A 1 816 ? 80.680 119.449 29.537 1.00 25.40 ? 816 ILE A C 1 ATOM 6578 O O . ILE A 1 816 ? 81.798 119.762 29.971 1.00 24.45 ? 816 ILE A O 1 ATOM 6579 C CB . ILE A 1 816 ? 80.066 121.493 28.192 1.00 25.50 ? 816 ILE A CB 1 ATOM 6580 C CG1 . ILE A 1 816 ? 79.008 122.569 27.953 1.00 25.11 ? 816 ILE A CG1 1 ATOM 6581 C CG2 . ILE A 1 816 ? 80.377 120.778 26.872 1.00 24.25 ? 816 ILE A CG2 1 ATOM 6582 C CD1 . ILE A 1 816 ? 79.481 123.711 27.073 1.00 24.70 ? 816 ILE A CD1 1 ATOM 6583 N N . LYS A 1 817 ? 80.351 118.191 29.283 1.00 24.20 ? 817 LYS A N 1 ATOM 6584 C CA . LYS A 1 817 ? 81.339 117.120 29.414 1.00 24.17 ? 817 LYS A CA 1 ATOM 6585 C C . LYS A 1 817 ? 81.774 116.702 28.002 1.00 24.31 ? 817 LYS A C 1 ATOM 6586 O O . LYS A 1 817 ? 80.927 116.425 27.154 1.00 24.31 ? 817 LYS A O 1 ATOM 6587 C CB . LYS A 1 817 ? 80.722 115.951 30.174 1.00 23.34 ? 817 LYS A CB 1 ATOM 6588 C CG . LYS A 1 817 ? 81.619 114.754 30.408 1.00 22.39 ? 817 LYS A CG 1 ATOM 6589 C CD . LYS A 1 817 ? 80.804 113.772 31.229 1.00 27.31 ? 817 LYS A CD 1 ATOM 6590 C CE . LYS A 1 817 ? 81.585 112.627 31.794 1.00 32.97 ? 817 LYS A CE 1 ATOM 6591 N NZ . LYS A 1 817 ? 80.614 111.768 32.551 1.00 35.97 ? 817 LYS A NZ 1 ATOM 6592 N N . ILE A 1 818 ? 83.081 116.699 27.743 1.00 23.71 ? 818 ILE A N 1 ATOM 6593 C CA . ILE A 1 818 ? 83.575 116.332 26.431 1.00 23.12 ? 818 ILE A CA 1 ATOM 6594 C C . ILE A 1 818 ? 84.346 115.027 26.553 1.00 23.28 ? 818 ILE A C 1 ATOM 6595 O O . ILE A 1 818 ? 85.332 114.927 27.296 1.00 22.62 ? 818 ILE A O 1 ATOM 6596 C CB . ILE A 1 818 ? 84.409 117.451 25.744 1.00 24.04 ? 818 ILE A CB 1 ATOM 6597 C CG1 . ILE A 1 818 ? 83.719 118.816 25.847 1.00 21.54 ? 818 ILE A CG1 1 ATOM 6598 C CG2 . ILE A 1 818 ? 84.671 117.088 24.268 1.00 23.52 ? 818 ILE A CG2 1 ATOM 6599 C CD1 . ILE A 1 818 ? 84.590 119.991 25.336 1.00 23.07 ? 818 ILE A CD1 1 ATOM 6600 N N . LEU A 1 819 ? 83.860 114.003 25.851 1.00 23.12 ? 819 LEU A N 1 ATOM 6601 C CA . LEU A 1 819 ? 84.541 112.710 25.840 1.00 23.55 ? 819 LEU A CA 1 ATOM 6602 C C . LEU A 1 819 ? 85.434 112.548 24.614 1.00 24.11 ? 819 LEU A C 1 ATOM 6603 O O . LEU A 1 819 ? 85.084 113.017 23.535 1.00 24.64 ? 819 LEU A O 1 ATOM 6604 C CB . LEU A 1 819 ? 83.523 111.587 25.893 1.00 22.92 ? 819 LEU A CB 1 ATOM 6605 C CG . LEU A 1 819 ? 82.384 111.818 26.903 1.00 24.42 ? 819 LEU A CG 1 ATOM 6606 C CD1 . LEU A 1 819 ? 81.376 110.680 26.854 1.00 19.14 ? 819 LEU A CD1 1 ATOM 6607 C CD2 . LEU A 1 819 ? 82.989 111.917 28.299 1.00 21.44 ? 819 LEU A CD2 1 ATOM 6608 N N . GLY A 1 820 ? 86.564 111.861 24.778 1.00 24.83 ? 820 GLY A N 1 ATOM 6609 C CA . GLY A 1 820 ? 87.475 111.548 23.661 1.00 25.79 ? 820 GLY A CA 1 ATOM 6610 C C . GLY A 1 820 ? 88.219 112.759 23.155 1.00 26.68 ? 820 GLY A C 1 ATOM 6611 O O . GLY A 1 820 ? 88.405 112.931 21.948 1.00 26.90 ? 820 GLY A O 1 ATOM 6612 N N . THR A 1 821 ? 88.628 113.620 24.080 1.00 26.76 ? 821 THR A N 1 ATOM 6613 C CA . THR A 1 821 ? 89.208 114.914 23.723 1.00 27.92 ? 821 THR A CA 1 ATOM 6614 C C . THR A 1 821 ? 90.605 115.037 24.314 1.00 28.49 ? 821 THR A C 1 ATOM 6615 O O . THR A 1 821 ? 90.921 114.442 25.349 1.00 27.48 ? 821 THR A O 1 ATOM 6616 C CB . THR A 1 821 ? 88.297 116.088 24.218 1.00 28.53 ? 821 THR A CB 1 ATOM 6617 O OG1 . THR A 1 821 ? 88.724 117.341 23.653 1.00 29.13 ? 821 THR A OG1 1 ATOM 6618 C CG2 . THR A 1 821 ? 88.255 116.162 25.761 1.00 26.95 ? 821 THR A CG2 1 ATOM 6619 N N . GLU A 1 822 ? 91.450 115.767 23.604 1.00 29.91 ? 822 GLU A N 1 ATOM 6620 C CA . GLU A 1 822 ? 92.699 116.249 24.140 1.00 31.02 ? 822 GLU A CA 1 ATOM 6621 C C . GLU A 1 822 ? 92.370 117.435 25.058 1.00 31.59 ? 822 GLU A C 1 ATOM 6622 O O . GLU A 1 822 ? 91.274 118.015 24.968 1.00 31.11 ? 822 GLU A O 1 ATOM 6623 C CB . GLU A 1 822 ? 93.634 116.669 22.981 1.00 31.89 ? 822 GLU A CB 1 ATOM 6624 C CG . GLU A 1 822 ? 94.203 115.484 22.158 1.00 33.65 ? 822 GLU A CG 1 ATOM 6625 C CD . GLU A 1 822 ? 94.846 114.405 23.036 1.00 38.07 ? 822 GLU A CD 1 ATOM 6626 O OE1 . GLU A 1 822 ? 95.561 114.767 23.986 1.00 41.45 ? 822 GLU A OE1 1 ATOM 6627 O OE2 . GLU A 1 822 ? 94.631 113.191 22.801 1.00 41.86 ? 822 GLU A OE2 1 ATOM 6628 N N . GLU A 1 823 ? 93.299 117.802 25.942 1.00 32.47 ? 823 GLU A N 1 ATOM 6629 C CA . GLU A 1 823 ? 93.039 118.878 26.901 1.00 33.63 ? 823 GLU A CA 1 ATOM 6630 C C . GLU A 1 823 ? 92.625 120.194 26.242 1.00 34.10 ? 823 GLU A C 1 ATOM 6631 O O . GLU A 1 823 ? 93.418 120.785 25.506 1.00 34.40 ? 823 GLU A O 1 ATOM 6632 C CB . GLU A 1 823 ? 94.261 119.103 27.805 1.00 33.69 ? 823 GLU A CB 1 ATOM 6633 C CG . GLU A 1 823 ? 94.068 120.284 28.733 1.00 34.59 ? 823 GLU A CG 1 ATOM 6634 C CD . GLU A 1 823 ? 94.918 120.229 29.976 1.00 37.12 ? 823 GLU A CD 1 ATOM 6635 O OE1 . GLU A 1 823 ? 96.101 119.786 29.899 1.00 36.33 ? 823 GLU A OE1 1 ATOM 6636 O OE2 . GLU A 1 823 ? 94.379 120.652 31.031 1.00 38.10 ? 823 GLU A OE2 1 ATOM 6637 N N . PRO A 1 824 ? 91.381 120.653 26.477 1.00 34.56 ? 824 PRO A N 1 ATOM 6638 C CA . PRO A 1 824 ? 91.002 121.964 25.946 1.00 34.95 ? 824 PRO A CA 1 ATOM 6639 C C . PRO A 1 824 ? 91.511 123.066 26.867 1.00 36.06 ? 824 PRO A C 1 ATOM 6640 O O . PRO A 1 824 ? 91.413 122.948 28.096 1.00 35.35 ? 824 PRO A O 1 ATOM 6641 C CB . PRO A 1 824 ? 89.473 121.945 25.976 1.00 35.17 ? 824 PRO A CB 1 ATOM 6642 C CG . PRO A 1 824 ? 89.071 120.693 26.649 1.00 34.57 ? 824 PRO A CG 1 ATOM 6643 C CD . PRO A 1 824 ? 90.280 120.016 27.212 1.00 34.15 ? 824 PRO A CD 1 ATOM 6644 N N . SER A 1 825 ? 92.090 124.114 26.293 1.00 37.07 ? 825 SER A N 1 ATOM 6645 C CA . SER A 1 825 ? 92.544 125.245 27.115 1.00 38.90 ? 825 SER A CA 1 ATOM 6646 C C . SER A 1 825 ? 92.100 126.584 26.574 1.00 39.41 ? 825 SER A C 1 ATOM 6647 O O . SER A 1 825 ? 91.694 126.696 25.403 1.00 39.52 ? 825 SER A O 1 ATOM 6648 C CB . SER A 1 825 ? 94.047 125.206 27.376 1.00 38.76 ? 825 SER A CB 1 ATOM 6649 O OG . SER A 1 825 ? 94.720 124.535 26.346 1.00 42.16 ? 825 SER A OG 1 ATOM 6650 N N . ASN A 1 826 ? 92.142 127.587 27.451 1.00 40.11 ? 826 ASN A N 1 ATOM 6651 C CA . ASN A 1 826 ? 91.707 128.945 27.138 1.00 41.18 ? 826 ASN A CA 1 ATOM 6652 C C . ASN A 1 826 ? 90.313 128.957 26.546 1.00 40.88 ? 826 ASN A C 1 ATOM 6653 O O . ASN A 1 826 ? 90.108 129.450 25.434 1.00 41.65 ? 826 ASN A O 1 ATOM 6654 C CB . ASN A 1 826 ? 92.699 129.648 26.192 1.00 42.07 ? 826 ASN A CB 1 ATOM 6655 C CG . ASN A 1 826 ? 94.144 129.555 26.674 1.00 44.90 ? 826 ASN A CG 1 ATOM 6656 O OD1 . ASN A 1 826 ? 94.410 129.541 27.885 1.00 47.59 ? 826 ASN A OD1 1 ATOM 6657 N ND2 . ASN A 1 826 ? 95.092 129.483 25.724 1.00 48.23 ? 826 ASN A ND2 1 ATOM 6658 N N . VAL A 1 827 ? 89.354 128.408 27.291 1.00 40.26 ? 827 VAL A N 1 ATOM 6659 C CA . VAL A 1 827 ? 87.976 128.291 26.805 1.00 39.07 ? 827 VAL A CA 1 ATOM 6660 C C . VAL A 1 827 ? 87.304 129.661 26.790 1.00 38.92 ? 827 VAL A C 1 ATOM 6661 O O . VAL A 1 827 ? 87.350 130.408 27.755 1.00 38.74 ? 827 VAL A O 1 ATOM 6662 C CB . VAL A 1 827 ? 87.167 127.196 27.578 1.00 38.74 ? 827 VAL A CB 1 ATOM 6663 C CG1 . VAL A 1 827 ? 85.681 127.262 27.286 1.00 37.76 ? 827 VAL A CG1 1 ATOM 6664 C CG2 . VAL A 1 827 ? 87.694 125.846 27.213 1.00 38.92 ? 827 VAL A CG2 1 ATOM 6665 N N . THR A 1 828 ? 86.691 129.964 25.662 1.00 38.41 ? 828 THR A N 1 ATOM 6666 C CA . THR A 1 828 ? 86.103 131.256 25.390 1.00 38.98 ? 828 THR A CA 1 ATOM 6667 C C . THR A 1 828 ? 84.648 131.006 25.036 1.00 38.34 ? 828 THR A C 1 ATOM 6668 O O . THR A 1 828 ? 84.338 129.999 24.421 1.00 37.77 ? 828 THR A O 1 ATOM 6669 C CB . THR A 1 828 ? 86.846 131.902 24.194 1.00 38.86 ? 828 THR A CB 1 ATOM 6670 O OG1 . THR A 1 828 ? 88.097 132.432 24.661 1.00 41.94 ? 828 THR A OG1 1 ATOM 6671 C CG2 . THR A 1 828 ? 86.048 133.016 23.565 1.00 40.05 ? 828 THR A CG2 1 ATOM 6672 N N . VAL A 1 829 ? 83.769 131.919 25.433 1.00 38.84 ? 829 VAL A N 1 ATOM 6673 C CA . VAL A 1 829 ? 82.343 131.826 25.130 1.00 39.32 ? 829 VAL A CA 1 ATOM 6674 C C . VAL A 1 829 ? 81.890 133.130 24.480 1.00 40.92 ? 829 VAL A C 1 ATOM 6675 O O . VAL A 1 829 ? 82.040 134.202 25.065 1.00 41.13 ? 829 VAL A O 1 ATOM 6676 C CB . VAL A 1 829 ? 81.497 131.558 26.411 1.00 38.97 ? 829 VAL A CB 1 ATOM 6677 C CG1 . VAL A 1 829 ? 79.977 131.583 26.100 1.00 38.81 ? 829 VAL A CG1 1 ATOM 6678 C CG2 . VAL A 1 829 ? 81.909 130.253 27.073 1.00 36.86 ? 829 VAL A CG2 1 ATOM 6679 N N . LYS A 1 830 ? 81.342 133.040 23.276 1.00 41.99 ? 830 LYS A N 1 ATOM 6680 C CA . LYS A 1 830 ? 80.817 134.207 22.597 1.00 44.35 ? 830 LYS A CA 1 ATOM 6681 C C . LYS A 1 830 ? 79.316 134.069 22.426 1.00 44.97 ? 830 LYS A C 1 ATOM 6682 O O . LYS A 1 830 ? 78.827 132.994 22.123 1.00 44.48 ? 830 LYS A O 1 ATOM 6683 C CB . LYS A 1 830 ? 81.497 134.392 21.234 1.00 44.52 ? 830 LYS A CB 1 ATOM 6684 C CG . LYS A 1 830 ? 82.947 134.870 21.290 1.00 45.78 ? 830 LYS A CG 1 ATOM 6685 C CD . LYS A 1 830 ? 83.599 134.788 19.888 1.00 46.06 ? 830 LYS A CD 1 ATOM 6686 C CE . LYS A 1 830 ? 85.086 135.221 19.900 1.00 48.61 ? 830 LYS A CE 1 ATOM 6687 N NZ . LYS A 1 830 ? 85.769 135.016 18.556 1.00 48.57 ? 830 LYS A NZ 1 ATOM 6688 N N . HIS A 1 831 ? 78.595 135.165 22.627 1.00 46.73 ? 831 HIS A N 1 ATOM 6689 C CA . HIS A 1 831 ? 77.142 135.186 22.523 1.00 48.82 ? 831 HIS A CA 1 ATOM 6690 C C . HIS A 1 831 ? 76.685 136.132 21.395 1.00 50.49 ? 831 HIS A C 1 ATOM 6691 O O . HIS A 1 831 ? 76.790 137.361 21.515 1.00 50.47 ? 831 HIS A O 1 ATOM 6692 C CB . HIS A 1 831 ? 76.526 135.571 23.881 1.00 48.45 ? 831 HIS A CB 1 ATOM 6693 C CG . HIS A 1 831 ? 75.038 135.748 23.858 1.00 48.63 ? 831 HIS A CG 1 ATOM 6694 N ND1 . HIS A 1 831 ? 74.382 136.616 24.704 1.00 49.73 ? 831 HIS A ND1 1 ATOM 6695 C CD2 . HIS A 1 831 ? 74.074 135.164 23.103 1.00 48.92 ? 831 HIS A CD2 1 ATOM 6696 C CE1 . HIS A 1 831 ? 73.080 136.564 24.470 1.00 49.05 ? 831 HIS A CE1 1 ATOM 6697 N NE2 . HIS A 1 831 ? 72.868 135.690 23.503 1.00 48.38 ? 831 HIS A NE2 1 ATOM 6698 N N . ASN A 1 832 ? 76.164 135.549 20.312 1.00 52.54 ? 832 ASN A N 1 ATOM 6699 C CA . ASN A 1 832 ? 75.894 136.290 19.073 1.00 54.71 ? 832 ASN A CA 1 ATOM 6700 C C . ASN A 1 832 ? 77.064 137.179 18.656 1.00 55.57 ? 832 ASN A C 1 ATOM 6701 O O . ASN A 1 832 ? 76.879 138.346 18.297 1.00 56.13 ? 832 ASN A O 1 ATOM 6702 C CB . ASN A 1 832 ? 74.604 137.104 19.189 1.00 55.10 ? 832 ASN A CB 1 ATOM 6703 C CG . ASN A 1 832 ? 73.373 136.249 19.036 1.00 57.24 ? 832 ASN A CG 1 ATOM 6704 O OD1 . ASN A 1 832 ? 73.181 135.579 18.005 1.00 59.79 ? 832 ASN A OD1 1 ATOM 6705 N ND2 . ASN A 1 832 ? 72.522 136.258 20.062 1.00 58.57 ? 832 ASN A ND2 1 ATOM 6706 N N . GLY A 1 833 ? 78.269 136.619 18.735 1.00 56.49 ? 833 GLY A N 1 ATOM 6707 C CA . GLY A 1 833 ? 79.466 137.318 18.318 1.00 57.82 ? 833 GLY A CA 1 ATOM 6708 C C . GLY A 1 833 ? 80.265 137.913 19.453 1.00 58.89 ? 833 GLY A C 1 ATOM 6709 O O . GLY A 1 833 ? 81.487 137.824 19.449 1.00 59.30 ? 833 GLY A O 1 ATOM 6710 N N . VAL A 1 834 ? 79.579 138.524 20.419 1.00 60.10 ? 834 VAL A N 1 ATOM 6711 C CA . VAL A 1 834 ? 80.228 139.262 21.517 1.00 60.94 ? 834 VAL A CA 1 ATOM 6712 C C . VAL A 1 834 ? 80.922 138.305 22.501 1.00 61.55 ? 834 VAL A C 1 ATOM 6713 O O . VAL A 1 834 ? 80.270 137.416 23.047 1.00 61.39 ? 834 VAL A O 1 ATOM 6714 C CB . VAL A 1 834 ? 79.218 140.148 22.326 1.00 60.87 ? 834 VAL A CB 1 ATOM 6715 C CG1 . VAL A 1 834 ? 79.957 141.151 23.207 1.00 60.95 ? 834 VAL A CG1 1 ATOM 6716 C CG2 . VAL A 1 834 ? 78.236 140.879 21.409 1.00 61.34 ? 834 VAL A CG2 1 ATOM 6717 N N . PRO A 1 835 ? 82.247 138.480 22.724 1.00 62.26 ? 835 PRO A N 1 ATOM 6718 C CA . PRO A 1 835 ? 82.970 137.737 23.766 1.00 62.66 ? 835 PRO A CA 1 ATOM 6719 C C . PRO A 1 835 ? 82.383 137.897 25.166 1.00 63.24 ? 835 PRO A C 1 ATOM 6720 O O . PRO A 1 835 ? 81.534 138.758 25.398 1.00 63.47 ? 835 PRO A O 1 ATOM 6721 C CB . PRO A 1 835 ? 84.375 138.339 23.713 1.00 62.48 ? 835 PRO A CB 1 ATOM 6722 C CG . PRO A 1 835 ? 84.523 138.800 22.299 1.00 62.88 ? 835 PRO A CG 1 ATOM 6723 C CD . PRO A 1 835 ? 83.159 139.348 21.953 1.00 62.60 ? 835 PRO A CD 1 ATOM 6724 N N . SER A 1 836 ? 82.861 137.062 26.086 1.00 63.89 ? 836 SER A N 1 ATOM 6725 C CA . SER A 1 836 ? 82.428 137.027 27.489 1.00 64.21 ? 836 SER A CA 1 ATOM 6726 C C . SER A 1 836 ? 80.961 136.663 27.616 1.00 64.09 ? 836 SER A C 1 ATOM 6727 O O . SER A 1 836 ? 80.651 135.594 28.125 1.00 63.98 ? 836 SER A O 1 ATOM 6728 C CB . SER A 1 836 ? 82.753 138.331 28.237 1.00 64.25 ? 836 SER A CB 1 ATOM 6729 O OG . SER A 1 836 ? 82.687 138.154 29.647 1.00 65.09 ? 836 SER A OG 1 ATOM 6730 N N . THR A 1 838 ? 82.730 134.903 30.694 1.00 49.64 ? 838 THR A N 1 ATOM 6731 C CA . THR A 1 838 ? 84.107 135.410 30.682 1.00 49.21 ? 838 THR A CA 1 ATOM 6732 C C . THR A 1 838 ? 85.140 134.289 30.492 1.00 48.35 ? 838 THR A C 1 ATOM 6733 O O . THR A 1 838 ? 85.662 134.093 29.374 1.00 49.30 ? 838 THR A O 1 ATOM 6734 C CB . THR A 1 838 ? 84.454 136.204 31.969 1.00 50.08 ? 838 THR A CB 1 ATOM 6735 O OG1 . THR A 1 838 ? 83.280 136.362 32.780 1.00 50.15 ? 838 THR A OG1 1 ATOM 6736 C CG2 . THR A 1 838 ? 85.074 137.593 31.617 1.00 50.66 ? 838 THR A CG2 1 ATOM 6737 N N . SER A 1 839 ? 85.468 133.567 31.564 1.00 45.75 ? 839 SER A N 1 ATOM 6738 C CA . SER A 1 839 ? 86.328 132.390 31.410 1.00 43.62 ? 839 SER A CA 1 ATOM 6739 C C . SER A 1 839 ? 85.885 131.184 32.260 1.00 41.26 ? 839 SER A C 1 ATOM 6740 O O . SER A 1 839 ? 86.070 131.178 33.494 1.00 41.13 ? 839 SER A O 1 ATOM 6741 C CB . SER A 1 839 ? 87.800 132.717 31.656 1.00 44.00 ? 839 SER A CB 1 ATOM 6742 O OG . SER A 1 839 ? 88.596 131.582 31.323 1.00 46.31 ? 839 SER A OG 1 ATOM 6743 N N . PRO A 1 840 ? 85.298 130.163 31.596 1.00 38.37 ? 840 PRO A N 1 ATOM 6744 C CA . PRO A 1 840 ? 84.828 128.956 32.250 1.00 35.78 ? 840 PRO A CA 1 ATOM 6745 C C . PRO A 1 840 ? 85.954 128.152 32.894 1.00 33.51 ? 840 PRO A C 1 ATOM 6746 O O . PRO A 1 840 ? 87.112 128.267 32.494 1.00 32.45 ? 840 PRO A O 1 ATOM 6747 C CB . PRO A 1 840 ? 84.218 128.157 31.091 1.00 35.80 ? 840 PRO A CB 1 ATOM 6748 C CG . PRO A 1 840 ? 83.876 129.184 30.076 1.00 37.37 ? 840 PRO A CG 1 ATOM 6749 C CD . PRO A 1 840 ? 85.007 130.132 30.153 1.00 38.00 ? 840 PRO A CD 1 ATOM 6750 N N . THR A 1 841 ? 85.594 127.318 33.865 1.00 30.69 ? 841 THR A N 1 ATOM 6751 C CA . THR A 1 841 ? 86.528 126.376 34.492 1.00 29.03 ? 841 THR A CA 1 ATOM 6752 C C . THR A 1 841 ? 86.555 125.099 33.679 1.00 28.43 ? 841 THR A C 1 ATOM 6753 O O . THR A 1 841 ? 85.506 124.636 33.216 1.00 28.54 ? 841 THR A O 1 ATOM 6754 C CB . THR A 1 841 ? 86.075 126.078 35.951 1.00 28.87 ? 841 THR A CB 1 ATOM 6755 O OG1 . THR A 1 841 ? 86.172 127.285 36.707 1.00 28.46 ? 841 THR A OG1 1 ATOM 6756 C CG2 . THR A 1 841 ? 86.899 124.974 36.627 1.00 27.32 ? 841 THR A CG2 1 ATOM 6757 N N . VAL A 1 842 ? 87.737 124.533 33.499 1.00 26.97 ? 842 VAL A N 1 ATOM 6758 C CA . VAL A 1 842 ? 87.877 123.233 32.851 1.00 26.29 ? 842 VAL A CA 1 ATOM 6759 C C . VAL A 1 842 ? 88.608 122.311 33.777 1.00 26.10 ? 842 VAL A C 1 ATOM 6760 O O . VAL A 1 842 ? 89.682 122.652 34.317 1.00 26.05 ? 842 VAL A O 1 ATOM 6761 C CB . VAL A 1 842 ? 88.694 123.304 31.544 1.00 26.68 ? 842 VAL A CB 1 ATOM 6762 C CG1 . VAL A 1 842 ? 88.887 121.909 30.945 1.00 26.38 ? 842 VAL A CG1 1 ATOM 6763 C CG2 . VAL A 1 842 ? 88.053 124.281 30.581 1.00 25.63 ? 842 VAL A CG2 1 ATOM 6764 N N . THR A 1 843 ? 88.021 121.144 33.983 1.00 25.22 ? 843 THR A N 1 ATOM 6765 C CA . THR A 1 843 ? 88.688 120.052 34.688 1.00 25.00 ? 843 THR A CA 1 ATOM 6766 C C . THR A 1 843 ? 89.016 118.994 33.628 1.00 25.14 ? 843 THR A C 1 ATOM 6767 O O . THR A 1 843 ? 88.165 118.666 32.790 1.00 24.71 ? 843 THR A O 1 ATOM 6768 C CB . THR A 1 843 ? 87.764 119.453 35.792 1.00 24.41 ? 843 THR A CB 1 ATOM 6769 O OG1 . THR A 1 843 ? 87.184 120.533 36.547 1.00 27.67 ? 843 THR A OG1 1 ATOM 6770 C CG2 . THR A 1 843 ? 88.530 118.537 36.751 1.00 23.60 ? 843 THR A CG2 1 ATOM 6771 N N . TYR A 1 844 ? 90.237 118.463 33.657 1.00 24.86 ? 844 TYR A N 1 ATOM 6772 C CA . TYR A 1 844 ? 90.662 117.532 32.638 1.00 24.35 ? 844 TYR A CA 1 ATOM 6773 C C . TYR A 1 844 ? 91.344 116.301 33.225 1.00 24.87 ? 844 TYR A C 1 ATOM 6774 O O . TYR A 1 844 ? 92.134 116.404 34.169 1.00 23.51 ? 844 TYR A O 1 ATOM 6775 C CB . TYR A 1 844 ? 91.551 118.238 31.604 1.00 25.23 ? 844 TYR A CB 1 ATOM 6776 C CG . TYR A 1 844 ? 91.931 117.307 30.466 1.00 24.69 ? 844 TYR A CG 1 ATOM 6777 C CD1 . TYR A 1 844 ? 90.967 116.880 29.541 1.00 25.18 ? 844 TYR A CD1 1 ATOM 6778 C CD2 . TYR A 1 844 ? 93.217 116.821 30.346 1.00 24.59 ? 844 TYR A CD2 1 ATOM 6779 C CE1 . TYR A 1 844 ? 91.289 116.025 28.499 1.00 24.43 ? 844 TYR A CE1 1 ATOM 6780 C CE2 . TYR A 1 844 ? 93.566 115.932 29.292 1.00 25.67 ? 844 TYR A CE2 1 ATOM 6781 C CZ . TYR A 1 844 ? 92.584 115.546 28.381 1.00 26.38 ? 844 TYR A CZ 1 ATOM 6782 O OH . TYR A 1 844 ? 92.891 114.693 27.349 1.00 24.99 ? 844 TYR A OH 1 ATOM 6783 N N . ASP A 1 845 ? 90.973 115.135 32.694 1.00 24.73 ? 845 ASP A N 1 ATOM 6784 C CA . ASP A 1 845 ? 91.462 113.839 33.122 1.00 26.78 ? 845 ASP A CA 1 ATOM 6785 C C . ASP A 1 845 ? 92.226 113.286 31.918 1.00 27.49 ? 845 ASP A C 1 ATOM 6786 O O . ASP A 1 845 ? 91.613 112.797 30.967 1.00 26.93 ? 845 ASP A O 1 ATOM 6787 C CB . ASP A 1 845 ? 90.272 112.911 33.479 1.00 26.95 ? 845 ASP A CB 1 ATOM 6788 C CG . ASP A 1 845 ? 90.710 111.528 33.978 1.00 31.46 ? 845 ASP A CG 1 ATOM 6789 O OD1 . ASP A 1 845 ? 91.809 111.021 33.567 1.00 29.99 ? 845 ASP A OD1 1 ATOM 6790 O OD2 . ASP A 1 845 ? 89.923 110.924 34.767 1.00 33.37 ? 845 ASP A OD2 1 ATOM 6791 N N . SER A 1 846 ? 93.556 113.366 31.942 1.00 28.18 ? 846 SER A N 1 ATOM 6792 C CA . SER A 1 846 ? 94.348 112.984 30.769 1.00 29.18 ? 846 SER A CA 1 ATOM 6793 C C . SER A 1 846 ? 94.353 111.490 30.510 1.00 29.58 ? 846 SER A C 1 ATOM 6794 O O . SER A 1 846 ? 94.551 111.066 29.384 1.00 30.62 ? 846 SER A O 1 ATOM 6795 C CB . SER A 1 846 ? 95.781 113.525 30.878 1.00 29.82 ? 846 SER A CB 1 ATOM 6796 O OG . SER A 1 846 ? 96.335 113.036 32.092 1.00 31.61 ? 846 SER A OG 1 ATOM 6797 N N . ASN A 1 847 ? 94.133 110.693 31.549 1.00 29.77 ? 847 ASN A N 1 ATOM 6798 C CA . ASN A 1 847 ? 93.950 109.246 31.440 1.00 31.20 ? 847 ASN A CA 1 ATOM 6799 C C . ASN A 1 847 ? 92.689 108.837 30.624 1.00 30.43 ? 847 ASN A C 1 ATOM 6800 O O . ASN A 1 847 ? 92.760 107.982 29.738 1.00 30.51 ? 847 ASN A O 1 ATOM 6801 C CB . ASN A 1 847 ? 93.868 108.653 32.852 1.00 32.48 ? 847 ASN A CB 1 ATOM 6802 C CG . ASN A 1 847 ? 93.748 107.132 32.863 1.00 39.11 ? 847 ASN A CG 1 ATOM 6803 O OD1 . ASN A 1 847 ? 92.978 106.554 33.670 1.00 43.41 ? 847 ASN A OD1 1 ATOM 6804 N ND2 . ASN A 1 847 ? 94.533 106.460 31.992 1.00 44.37 ? 847 ASN A ND2 1 ATOM 6805 N N . LEU A 1 848 ? 91.557 109.467 30.928 1.00 28.93 ? 848 LEU A N 1 ATOM 6806 C CA . LEU A 1 848 ? 90.274 109.091 30.355 1.00 28.31 ? 848 LEU A CA 1 ATOM 6807 C C . LEU A 1 848 ? 89.924 109.919 29.128 1.00 26.78 ? 848 LEU A C 1 ATOM 6808 O O . LEU A 1 848 ? 89.004 109.588 28.394 1.00 26.34 ? 848 LEU A O 1 ATOM 6809 C CB . LEU A 1 848 ? 89.182 109.201 31.423 1.00 28.55 ? 848 LEU A CB 1 ATOM 6810 C CG . LEU A 1 848 ? 88.763 107.958 32.230 1.00 29.69 ? 848 LEU A CG 1 ATOM 6811 C CD1 . LEU A 1 848 ? 89.861 106.915 32.396 1.00 31.67 ? 848 LEU A CD1 1 ATOM 6812 C CD2 . LEU A 1 848 ? 88.195 108.337 33.563 1.00 28.04 ? 848 LEU A CD2 1 ATOM 6813 N N . LYS A 1 849 ? 90.676 110.991 28.911 1.00 25.92 ? 849 LYS A N 1 ATOM 6814 C CA . LYS A 1 849 ? 90.424 111.924 27.817 1.00 24.59 ? 849 LYS A CA 1 ATOM 6815 C C . LYS A 1 849 ? 89.074 112.655 27.972 1.00 24.28 ? 849 LYS A C 1 ATOM 6816 O O . LYS A 1 849 ? 88.412 112.973 26.982 1.00 22.75 ? 849 LYS A O 1 ATOM 6817 C CB . LYS A 1 849 ? 90.562 111.198 26.459 1.00 25.54 ? 849 LYS A CB 1 ATOM 6818 C CG . LYS A 1 849 ? 91.937 110.465 26.295 1.00 24.21 ? 849 LYS A CG 1 ATOM 6819 C CD . LYS A 1 849 ? 93.056 111.496 26.050 1.00 24.92 ? 849 LYS A CD 1 ATOM 6820 C CE . LYS A 1 849 ? 94.460 110.860 25.869 1.00 27.48 ? 849 LYS A CE 1 ATOM 6821 N NZ . LYS A 1 849 ? 95.527 111.933 25.541 1.00 28.30 ? 849 LYS A NZ 1 ATOM 6822 N N . VAL A 1 850 ? 88.711 112.951 29.225 1.00 23.07 ? 850 VAL A N 1 ATOM 6823 C CA . VAL A 1 850 ? 87.483 113.680 29.586 1.00 21.97 ? 850 VAL A CA 1 ATOM 6824 C C . VAL A 1 850 ? 87.785 115.103 30.071 1.00 22.54 ? 850 VAL A C 1 ATOM 6825 O O . VAL A 1 850 ? 88.606 115.296 30.967 1.00 22.15 ? 850 VAL A O 1 ATOM 6826 C CB . VAL A 1 850 ? 86.693 112.922 30.696 1.00 21.98 ? 850 VAL A CB 1 ATOM 6827 C CG1 . VAL A 1 850 ? 85.432 113.699 31.130 1.00 21.92 ? 850 VAL A CG1 1 ATOM 6828 C CG2 . VAL A 1 850 ? 86.313 111.505 30.222 1.00 21.18 ? 850 VAL A CG2 1 ATOM 6829 N N . ALA A 1 851 ? 87.124 116.088 29.468 1.00 22.94 ? 851 ALA A N 1 ATOM 6830 C CA . ALA A 1 851 ? 87.143 117.471 29.936 1.00 23.24 ? 851 ALA A CA 1 ATOM 6831 C C . ALA A 1 851 ? 85.750 117.790 30.406 1.00 24.06 ? 851 ALA A C 1 ATOM 6832 O O . ALA A 1 851 ? 84.779 117.418 29.741 1.00 23.26 ? 851 ALA A O 1 ATOM 6833 C CB . ALA A 1 851 ? 87.520 118.429 28.798 1.00 22.97 ? 851 ALA A CB 1 ATOM 6834 N N . ILE A 1 852 ? 85.641 118.490 31.537 1.00 24.38 ? 852 ILE A N 1 ATOM 6835 C CA . ILE A 1 852 ? 84.348 118.972 32.025 1.00 24.52 ? 852 ILE A CA 1 ATOM 6836 C C . ILE A 1 852 ? 84.496 120.451 32.197 1.00 24.56 ? 852 ILE A C 1 ATOM 6837 O O . ILE A 1 852 ? 85.398 120.890 32.897 1.00 24.57 ? 852 ILE A O 1 ATOM 6838 C CB . ILE A 1 852 ? 83.950 118.333 33.364 1.00 24.61 ? 852 ILE A CB 1 ATOM 6839 C CG1 . ILE A 1 852 ? 83.700 116.840 33.183 1.00 26.72 ? 852 ILE A CG1 1 ATOM 6840 C CG2 . ILE A 1 852 ? 82.700 118.992 33.901 1.00 26.49 ? 852 ILE A CG2 1 ATOM 6841 C CD1 . ILE A 1 852 ? 83.619 116.068 34.476 1.00 33.50 ? 852 ILE A CD1 1 ATOM 6842 N N . ILE A 1 853 ? 83.629 121.210 31.539 1.00 24.28 ? 853 ILE A N 1 ATOM 6843 C CA . ILE A 1 853 ? 83.654 122.652 31.568 1.00 24.49 ? 853 ILE A CA 1 ATOM 6844 C C . ILE A 1 853 ? 82.518 123.091 32.483 1.00 25.42 ? 853 ILE A C 1 ATOM 6845 O O . ILE A 1 853 ? 81.370 122.720 32.260 1.00 25.09 ? 853 ILE A O 1 ATOM 6846 C CB . ILE A 1 853 ? 83.454 123.269 30.149 1.00 24.67 ? 853 ILE A CB 1 ATOM 6847 C CG1 . ILE A 1 853 ? 84.525 122.785 29.171 1.00 24.74 ? 853 ILE A CG1 1 ATOM 6848 C CG2 . ILE A 1 853 ? 83.352 124.808 30.193 1.00 24.51 ? 853 ILE A CG2 1 ATOM 6849 C CD1 . ILE A 1 853 ? 84.196 123.121 27.710 1.00 23.55 ? 853 ILE A CD1 1 ATOM 6850 N N . THR A 1 854 ? 82.843 123.874 33.506 1.00 26.13 ? 854 THR A N 1 ATOM 6851 C CA . THR A 1 854 ? 81.853 124.383 34.468 1.00 27.67 ? 854 THR A CA 1 ATOM 6852 C C . THR A 1 854 ? 81.991 125.900 34.574 1.00 28.17 ? 854 THR A C 1 ATOM 6853 O O . THR A 1 854 ? 82.830 126.501 33.878 1.00 27.11 ? 854 THR A O 1 ATOM 6854 C CB . THR A 1 854 ? 82.028 123.759 35.865 1.00 27.87 ? 854 THR A CB 1 ATOM 6855 O OG1 . THR A 1 854 ? 83.415 123.786 36.227 1.00 29.34 ? 854 THR A OG1 1 ATOM 6856 C CG2 . THR A 1 854 ? 81.507 122.281 35.910 1.00 27.72 ? 854 THR A CG2 1 ATOM 6857 N N . ASP A 1 855 ? 81.171 126.521 35.423 1.00 28.65 ? 855 ASP A N 1 ATOM 6858 C CA . ASP A 1 855 ? 81.170 127.978 35.581 1.00 30.47 ? 855 ASP A CA 1 ATOM 6859 C C . ASP A 1 855 ? 80.849 128.624 34.237 1.00 30.38 ? 855 ASP A C 1 ATOM 6860 O O . ASP A 1 855 ? 81.508 129.559 33.802 1.00 29.99 ? 855 ASP A O 1 ATOM 6861 C CB . ASP A 1 855 ? 82.530 128.490 36.110 1.00 30.51 ? 855 ASP A CB 1 ATOM 6862 C CG . ASP A 1 855 ? 82.421 129.854 36.795 1.00 33.85 ? 855 ASP A CG 1 ATOM 6863 O OD1 . ASP A 1 855 ? 81.392 130.128 37.444 1.00 36.67 ? 855 ASP A OD1 1 ATOM 6864 O OD2 . ASP A 1 855 ? 83.378 130.658 36.693 1.00 37.21 ? 855 ASP A OD2 1 ATOM 6865 N N . ILE A 1 856 ? 79.837 128.094 33.573 1.00 30.97 ? 856 ILE A N 1 ATOM 6866 C CA . ILE A 1 856 ? 79.443 128.569 32.263 1.00 31.23 ? 856 ILE A CA 1 ATOM 6867 C C . ILE A 1 856 ? 77.952 128.780 32.374 1.00 31.12 ? 856 ILE A C 1 ATOM 6868 O O . ILE A 1 856 ? 77.312 128.153 33.191 1.00 31.42 ? 856 ILE A O 1 ATOM 6869 C CB . ILE A 1 856 ? 79.828 127.514 31.198 1.00 31.71 ? 856 ILE A CB 1 ATOM 6870 C CG1 . ILE A 1 856 ? 79.963 128.127 29.808 1.00 31.60 ? 856 ILE A CG1 1 ATOM 6871 C CG2 . ILE A 1 856 ? 78.846 126.305 31.195 1.00 33.02 ? 856 ILE A CG2 1 ATOM 6872 C CD1 . ILE A 1 856 ? 80.838 127.231 28.874 1.00 31.38 ? 856 ILE A CD1 1 ATOM 6873 N N . ASP A 1 857 ? 77.404 129.678 31.579 1.00 31.74 ? 857 ASP A N 1 ATOM 6874 C CA . ASP A 1 857 ? 76.007 130.014 31.669 1.00 32.88 ? 857 ASP A CA 1 ATOM 6875 C C . ASP A 1 857 ? 75.520 130.273 30.248 1.00 32.02 ? 857 ASP A C 1 ATOM 6876 O O . ASP A 1 857 ? 75.504 131.411 29.809 1.00 32.30 ? 857 ASP A O 1 ATOM 6877 C CB . ASP A 1 857 ? 75.867 131.263 32.544 1.00 34.10 ? 857 ASP A CB 1 ATOM 6878 C CG . ASP A 1 857 ? 74.422 131.576 32.944 1.00 38.57 ? 857 ASP A CG 1 ATOM 6879 O OD1 . ASP A 1 857 ? 73.528 130.717 32.803 1.00 43.97 ? 857 ASP A OD1 1 ATOM 6880 O OD2 . ASP A 1 857 ? 74.174 132.713 33.432 1.00 43.84 ? 857 ASP A OD2 1 ATOM 6881 N N . LEU A 1 858 ? 75.158 129.212 29.515 1.00 30.99 ? 858 LEU A N 1 ATOM 6882 C CA . LEU A 1 858 ? 74.574 129.373 28.169 1.00 29.77 ? 858 LEU A CA 1 ATOM 6883 C C . LEU A 1 858 ? 73.063 129.320 28.256 1.00 29.98 ? 858 LEU A C 1 ATOM 6884 O O . LEU A 1 858 ? 72.490 128.248 28.441 1.00 31.07 ? 858 LEU A O 1 ATOM 6885 C CB . LEU A 1 858 ? 75.086 128.313 27.181 1.00 28.42 ? 858 LEU A CB 1 ATOM 6886 C CG . LEU A 1 858 ? 76.558 127.925 27.242 1.00 28.70 ? 858 LEU A CG 1 ATOM 6887 C CD1 . LEU A 1 858 ? 76.887 126.900 26.183 1.00 27.18 ? 858 LEU A CD1 1 ATOM 6888 C CD2 . LEU A 1 858 ? 77.501 129.142 27.129 1.00 25.67 ? 858 LEU A CD2 1 ATOM 6889 N N . LEU A 1 859 ? 72.412 130.465 28.117 1.00 29.46 ? 859 LEU A N 1 ATOM 6890 C CA . LEU A 1 859 ? 70.978 130.515 28.247 1.00 29.88 ? 859 LEU A CA 1 ATOM 6891 C C . LEU A 1 859 ? 70.296 129.677 27.178 1.00 29.84 ? 859 LEU A C 1 ATOM 6892 O O . LEU A 1 859 ? 70.716 129.655 26.017 1.00 29.80 ? 859 LEU A O 1 ATOM 6893 C CB . LEU A 1 859 ? 70.474 131.959 28.190 1.00 30.24 ? 859 LEU A CB 1 ATOM 6894 C CG . LEU A 1 859 ? 71.058 132.952 29.207 1.00 30.97 ? 859 LEU A CG 1 ATOM 6895 C CD1 . LEU A 1 859 ? 70.419 134.339 29.023 1.00 32.32 ? 859 LEU A CD1 1 ATOM 6896 C CD2 . LEU A 1 859 ? 70.866 132.436 30.630 1.00 31.00 ? 859 LEU A CD2 1 ATOM 6897 N N . LEU A 1 860 ? 69.246 128.976 27.584 1.00 29.76 ? 860 LEU A N 1 ATOM 6898 C CA . LEU A 1 860 ? 68.509 128.131 26.658 1.00 29.37 ? 860 LEU A CA 1 ATOM 6899 C C . LEU A 1 860 ? 67.809 129.025 25.673 1.00 29.24 ? 860 LEU A C 1 ATOM 6900 O O . LEU A 1 860 ? 67.149 129.999 26.065 1.00 29.70 ? 860 LEU A O 1 ATOM 6901 C CB . LEU A 1 860 ? 67.526 127.248 27.408 1.00 29.24 ? 860 LEU A CB 1 ATOM 6902 C CG . LEU A 1 860 ? 66.594 126.410 26.538 1.00 28.83 ? 860 LEU A CG 1 ATOM 6903 C CD1 . LEU A 1 860 ? 67.361 125.278 25.884 1.00 28.35 ? 860 LEU A CD1 1 ATOM 6904 C CD2 . LEU A 1 860 ? 65.452 125.888 27.360 1.00 29.14 ? 860 LEU A CD2 1 ATOM 6905 N N . GLY A 1 861 ? 67.997 128.733 24.389 1.00 29.67 ? 861 GLY A N 1 ATOM 6906 C CA . GLY A 1 861 ? 67.292 129.444 23.327 1.00 29.46 ? 861 GLY A CA 1 ATOM 6907 C C . GLY A 1 861 ? 68.100 130.589 22.747 1.00 29.94 ? 861 GLY A C 1 ATOM 6908 O O . GLY A 1 861 ? 67.576 131.359 21.929 1.00 30.16 ? 861 GLY A O 1 ATOM 6909 N N . GLU A 1 862 ? 69.357 130.695 23.188 1.00 29.28 ? 862 GLU A N 1 ATOM 6910 C CA . GLU A 1 862 ? 70.328 131.678 22.715 1.00 29.49 ? 862 GLU A CA 1 ATOM 6911 C C . GLU A 1 862 ? 71.489 131.014 21.949 1.00 29.12 ? 862 GLU A C 1 ATOM 6912 O O . GLU A 1 862 ? 71.940 129.921 22.320 1.00 28.49 ? 862 GLU A O 1 ATOM 6913 C CB . GLU A 1 862 ? 70.917 132.437 23.906 1.00 29.26 ? 862 GLU A CB 1 ATOM 6914 C CG . GLU A 1 862 ? 69.970 133.393 24.573 1.00 33.05 ? 862 GLU A CG 1 ATOM 6915 C CD . GLU A 1 862 ? 69.552 134.547 23.676 1.00 37.14 ? 862 GLU A CD 1 ATOM 6916 O OE1 . GLU A 1 862 ? 70.384 135.061 22.882 1.00 37.70 ? 862 GLU A OE1 1 ATOM 6917 O OE2 . GLU A 1 862 ? 68.374 134.945 23.776 1.00 39.77 ? 862 GLU A OE2 1 ATOM 6918 N N . ALA A 1 863 ? 71.951 131.681 20.887 1.00 28.54 ? 863 ALA A N 1 ATOM 6919 C CA . ALA A 1 863 ? 73.051 131.207 20.081 1.00 28.88 ? 863 ALA A CA 1 ATOM 6920 C C . ALA A 1 863 ? 74.363 131.556 20.779 1.00 29.22 ? 863 ALA A C 1 ATOM 6921 O O . ALA A 1 863 ? 74.531 132.681 21.254 1.00 29.86 ? 863 ALA A O 1 ATOM 6922 C CB . ALA A 1 863 ? 72.999 131.867 18.714 1.00 29.16 ? 863 ALA A CB 1 ATOM 6923 N N . TYR A 1 864 ? 75.267 130.589 20.847 1.00 29.08 ? 864 TYR A N 1 ATOM 6924 C CA . TYR A 1 864 ? 76.606 130.730 21.435 1.00 28.98 ? 864 TYR A CA 1 ATOM 6925 C C . TYR A 1 864 ? 77.622 130.013 20.583 1.00 29.00 ? 864 TYR A C 1 ATOM 6926 O O . TYR A 1 864 ? 77.274 129.052 19.884 1.00 28.21 ? 864 TYR A O 1 ATOM 6927 C CB . TYR A 1 864 ? 76.690 130.081 22.824 1.00 28.92 ? 864 TYR A CB 1 ATOM 6928 C CG . TYR A 1 864 ? 75.920 130.801 23.886 1.00 29.66 ? 864 TYR A CG 1 ATOM 6929 C CD1 . TYR A 1 864 ? 76.500 131.838 24.627 1.00 30.02 ? 864 TYR A CD1 1 ATOM 6930 C CD2 . TYR A 1 864 ? 74.598 130.456 24.146 1.00 31.22 ? 864 TYR A CD2 1 ATOM 6931 C CE1 . TYR A 1 864 ? 75.759 132.510 25.601 1.00 30.84 ? 864 TYR A CE1 1 ATOM 6932 C CE2 . TYR A 1 864 ? 73.869 131.102 25.099 1.00 31.07 ? 864 TYR A CE2 1 ATOM 6933 C CZ . TYR A 1 864 ? 74.441 132.128 25.837 1.00 29.43 ? 864 TYR A CZ 1 ATOM 6934 O OH . TYR A 1 864 ? 73.660 132.743 26.802 1.00 29.53 ? 864 TYR A OH 1 ATOM 6935 N N . THR A 1 865 ? 78.875 130.487 20.656 1.00 29.45 ? 865 THR A N 1 ATOM 6936 C CA . THR A 1 865 ? 80.038 129.778 20.169 1.00 29.88 ? 865 THR A CA 1 ATOM 6937 C C . THR A 1 865 ? 80.979 129.613 21.354 1.00 30.44 ? 865 THR A C 1 ATOM 6938 O O . THR A 1 865 ? 81.272 130.584 22.048 1.00 31.11 ? 865 THR A O 1 ATOM 6939 C CB . THR A 1 865 ? 80.817 130.561 19.064 1.00 30.25 ? 865 THR A CB 1 ATOM 6940 O OG1 . THR A 1 865 ? 79.946 130.930 17.994 1.00 29.26 ? 865 THR A OG1 1 ATOM 6941 C CG2 . THR A 1 865 ? 81.933 129.683 18.483 1.00 30.68 ? 865 THR A CG2 1 ATOM 6942 N N . VAL A 1 866 ? 81.484 128.400 21.559 1.00 30.49 ? 866 VAL A N 1 ATOM 6943 C CA . VAL A 1 866 ? 82.406 128.085 22.653 1.00 30.25 ? 866 VAL A CA 1 ATOM 6944 C C . VAL A 1 866 ? 83.661 127.566 21.980 1.00 31.22 ? 866 VAL A C 1 ATOM 6945 O O . VAL A 1 866 ? 83.580 126.686 21.123 1.00 31.24 ? 866 VAL A O 1 ATOM 6946 C CB . VAL A 1 866 ? 81.788 127.049 23.654 1.00 29.72 ? 866 VAL A CB 1 ATOM 6947 C CG1 . VAL A 1 866 ? 82.785 126.626 24.732 1.00 27.53 ? 866 VAL A CG1 1 ATOM 6948 C CG2 . VAL A 1 866 ? 80.548 127.630 24.296 1.00 29.31 ? 866 VAL A CG2 1 ATOM 6949 N N . GLU A 1 867 ? 84.811 128.137 22.329 1.00 31.99 ? 867 GLU A N 1 ATOM 6950 C CA . GLU A 1 867 ? 86.057 127.881 21.600 1.00 33.15 ? 867 GLU A CA 1 ATOM 6951 C C . GLU A 1 867 ? 87.198 127.567 22.535 1.00 32.71 ? 867 GLU A C 1 ATOM 6952 O O . GLU A 1 867 ? 87.231 128.053 23.635 1.00 32.61 ? 867 GLU A O 1 ATOM 6953 C CB . GLU A 1 867 ? 86.429 129.086 20.741 1.00 33.68 ? 867 GLU A CB 1 ATOM 6954 C CG . GLU A 1 867 ? 85.432 129.355 19.626 1.00 38.44 ? 867 GLU A CG 1 ATOM 6955 C CD . GLU A 1 867 ? 85.904 130.438 18.677 1.00 43.39 ? 867 GLU A CD 1 ATOM 6956 O OE1 . GLU A 1 867 ? 86.009 131.604 19.109 1.00 47.20 ? 867 GLU A OE1 1 ATOM 6957 O OE2 . GLU A 1 867 ? 86.173 130.120 17.505 1.00 45.81 ? 867 GLU A OE2 1 ATOM 6958 N N . TRP A 1 868 ? 88.130 126.736 22.084 1.00 33.39 ? 868 TRP A N 1 ATOM 6959 C CA . TRP A 1 868 ? 89.284 126.354 22.898 1.00 33.83 ? 868 TRP A CA 1 ATOM 6960 C C . TRP A 1 868 ? 90.516 126.075 22.043 1.00 34.91 ? 868 TRP A C 1 ATOM 6961 O O . TRP A 1 868 ? 90.405 125.723 20.871 1.00 35.06 ? 868 TRP A O 1 ATOM 6962 C CB . TRP A 1 868 ? 88.972 125.129 23.769 1.00 32.75 ? 868 TRP A CB 1 ATOM 6963 C CG . TRP A 1 868 ? 88.540 123.907 23.014 1.00 31.38 ? 868 TRP A CG 1 ATOM 6964 C CD1 . TRP A 1 868 ? 89.335 122.910 22.542 1.00 30.94 ? 868 TRP A CD1 1 ATOM 6965 C CD2 . TRP A 1 868 ? 87.194 123.534 22.685 1.00 31.92 ? 868 TRP A CD2 1 ATOM 6966 N NE1 . TRP A 1 868 ? 88.574 121.935 21.924 1.00 31.92 ? 868 TRP A NE1 1 ATOM 6967 C CE2 . TRP A 1 868 ? 87.258 122.301 21.993 1.00 30.81 ? 868 TRP A CE2 1 ATOM 6968 C CE3 . TRP A 1 868 ? 85.937 124.134 22.894 1.00 31.66 ? 868 TRP A CE3 1 ATOM 6969 C CZ2 . TRP A 1 868 ? 86.112 121.650 21.512 1.00 33.29 ? 868 TRP A CZ2 1 ATOM 6970 C CZ3 . TRP A 1 868 ? 84.805 123.492 22.408 1.00 31.45 ? 868 TRP A CZ3 1 ATOM 6971 C CH2 . TRP A 1 868 ? 84.901 122.260 21.726 1.00 30.44 ? 868 TRP A CH2 1 ATOM 6972 N N . ALA A 1 869 ? 91.686 126.231 22.656 1.00 36.60 ? 869 ALA A N 1 ATOM 6973 C CA . ALA A 1 869 ? 92.959 125.800 22.065 1.00 37.70 ? 869 ALA A CA 1 ATOM 6974 C C . ALA A 1 869 ? 93.338 124.422 22.588 1.00 38.18 ? 869 ALA A C 1 ATOM 6975 O O . ALA A 1 869 ? 92.775 123.949 23.585 1.00 38.02 ? 869 ALA A O 1 ATOM 6976 C CB . ALA A 1 869 ? 94.055 126.800 22.421 1.00 37.88 ? 869 ALA A CB 1 ATOM 6977 N N . HIS A 1 870 ? 94.295 123.784 21.922 1.00 38.81 ? 870 HIS A N 1 ATOM 6978 C CA . HIS A 1 870 ? 94.870 122.543 22.415 1.00 39.95 ? 870 HIS A CA 1 ATOM 6979 C C . HIS A 1 870 ? 96.332 122.736 22.846 1.00 40.88 ? 870 HIS A C 1 ATOM 6980 O O . HIS A 1 870 ? 97.223 122.865 22.001 1.00 42.07 ? 870 HIS A O 1 ATOM 6981 C CB . HIS A 1 870 ? 94.739 121.425 21.377 1.00 40.02 ? 870 HIS A CB 1 ATOM 6982 C CG . HIS A 1 870 ? 93.353 120.855 21.277 1.00 40.40 ? 870 HIS A CG 1 ATOM 6983 N ND1 . HIS A 1 870 ? 92.707 120.277 22.348 1.00 40.90 ? 870 HIS A ND1 1 ATOM 6984 C CD2 . HIS A 1 870 ? 92.486 120.789 20.240 1.00 41.43 ? 870 HIS A CD2 1 ATOM 6985 C CE1 . HIS A 1 870 ? 91.502 119.881 21.979 1.00 40.75 ? 870 HIS A CE1 1 ATOM 6986 N NE2 . HIS A 1 870 ? 91.346 120.170 20.700 1.00 41.80 ? 870 HIS A NE2 1 HETATM 6987 O OAA . KTL B 2 . ? 41.225 84.142 30.767 1.00 36.11 ? 1001 KTL A OAA 1 HETATM 6988 O OAB . KTL B 2 . ? 42.374 95.541 36.128 1.00 23.87 ? 1001 KTL A OAB 1 HETATM 6989 O OAC . KTL B 2 . ? 43.638 86.119 30.198 1.00 28.82 ? 1001 KTL A OAC 1 HETATM 6990 O OAD . KTL B 2 . ? 47.010 95.246 33.925 1.00 25.95 ? 1001 KTL A OAD 1 HETATM 6991 O OAE . KTL B 2 . ? 44.050 90.967 31.957 1.00 24.30 ? 1001 KTL A OAE 1 HETATM 6992 O OAF . KTL B 2 . ? 44.443 86.319 32.779 1.00 24.99 ? 1001 KTL A OAF 1 HETATM 6993 O OAG . KTL B 2 . ? 45.998 95.085 36.657 1.00 20.52 ? 1001 KTL A OAG 1 HETATM 6994 O OAH . KTL B 2 . ? 41.683 88.668 32.134 1.00 22.75 ? 1001 KTL A OAH 1 HETATM 6995 O OAI . KTL B 2 . ? 44.560 87.097 35.675 1.00 31.15 ? 1001 KTL A OAI 1 HETATM 6996 O OAJ . KTL B 2 . ? 44.526 89.281 36.571 1.00 29.78 ? 1001 KTL A OAJ 1 HETATM 6997 O OAK . KTL B 2 . ? 42.555 87.837 36.856 1.00 29.74 ? 1001 KTL A OAK 1 HETATM 6998 C CAL . KTL B 2 . ? 42.375 84.521 31.558 1.00 32.77 ? 1001 KTL A CAL 1 HETATM 6999 C CAM . KTL B 2 . ? 42.984 94.328 36.601 1.00 21.88 ? 1001 KTL A CAM 1 HETATM 7000 C CAN . KTL B 2 . ? 45.026 93.736 33.309 1.00 23.48 ? 1001 KTL A CAN 1 HETATM 7001 C CAO . KTL B 2 . ? 43.875 91.553 34.349 1.00 24.34 ? 1001 KTL A CAO 1 HETATM 7002 O OAP . KTL B 2 . ? 42.912 88.771 34.624 1.00 29.80 ? 1001 KTL A OAP 1 HETATM 7003 C CAQ . KTL B 2 . ? 42.666 86.002 31.244 1.00 29.37 ? 1001 KTL A CAQ 1 HETATM 7004 C CAR . KTL B 2 . ? 46.026 94.270 34.354 1.00 22.77 ? 1001 KTL A CAR 1 HETATM 7005 C CAS . KTL B 2 . ? 43.424 90.632 33.198 1.00 25.78 ? 1001 KTL A CAS 1 HETATM 7006 C CAT . KTL B 2 . ? 43.121 86.756 32.495 1.00 27.37 ? 1001 KTL A CAT 1 HETATM 7007 C CAU . KTL B 2 . ? 45.201 94.847 35.496 1.00 22.52 ? 1001 KTL A CAU 1 HETATM 7008 C CAV . KTL B 2 . ? 43.056 88.284 32.316 1.00 25.81 ? 1001 KTL A CAV 1 HETATM 7009 C CAW . KTL B 2 . ? 44.109 93.796 35.721 1.00 22.73 ? 1001 KTL A CAW 1 HETATM 7010 C CAX . KTL B 2 . ? 43.642 89.129 33.462 1.00 26.12 ? 1001 KTL A CAX 1 HETATM 7011 S SAY . KTL B 2 . ? 43.685 93.226 34.188 1.00 24.99 ? 1001 KTL A SAY 1 HETATM 7012 S SAZ . KTL B 2 . ? 43.661 88.237 35.966 1.00 29.17 ? 1001 KTL A SAZ 1 HETATM 7013 C C1 . NAG C 3 . ? 63.828 118.866 43.865 1.00 31.77 ? 2001 NAG A C1 1 HETATM 7014 C C2 . NAG C 3 . ? 64.333 120.297 44.063 1.00 31.96 ? 2001 NAG A C2 1 HETATM 7015 C C3 . NAG C 3 . ? 64.093 120.761 45.508 1.00 34.48 ? 2001 NAG A C3 1 HETATM 7016 C C4 . NAG C 3 . ? 62.626 120.649 45.931 1.00 38.76 ? 2001 NAG A C4 1 HETATM 7017 C C5 . NAG C 3 . ? 62.048 119.292 45.538 1.00 38.35 ? 2001 NAG A C5 1 HETATM 7018 C C6 . NAG C 3 . ? 60.535 119.436 45.437 1.00 39.35 ? 2001 NAG A C6 1 HETATM 7019 C C7 . NAG C 3 . ? 66.280 121.370 43.042 1.00 35.26 ? 2001 NAG A C7 1 HETATM 7020 C C8 . NAG C 3 . ? 67.747 121.306 42.690 1.00 31.94 ? 2001 NAG A C8 1 HETATM 7021 N N2 . NAG C 3 . ? 65.744 120.336 43.718 1.00 31.40 ? 2001 NAG A N2 1 HETATM 7022 O O3 . NAG C 3 . ? 64.479 122.102 45.657 1.00 33.45 ? 2001 NAG A O3 1 HETATM 7023 O O4 . NAG C 3 . ? 62.462 120.672 47.341 1.00 44.10 ? 2001 NAG A O4 1 HETATM 7024 O O5 . NAG C 3 . ? 62.498 118.721 44.315 1.00 33.81 ? 2001 NAG A O5 1 HETATM 7025 O O6 . NAG C 3 . ? 60.042 118.186 45.847 1.00 44.11 ? 2001 NAG A O6 1 HETATM 7026 O O7 . NAG C 3 . ? 65.630 122.382 42.716 1.00 36.98 ? 2001 NAG A O7 1 HETATM 7027 C C1 . NAG D 3 . ? 62.628 121.946 48.015 1.00 50.49 ? 2002 NAG A C1 1 HETATM 7028 C C2 . NAG D 3 . ? 61.492 122.121 49.031 1.00 54.00 ? 2002 NAG A C2 1 HETATM 7029 C C3 . NAG D 3 . ? 60.867 123.526 49.003 1.00 53.83 ? 2002 NAG A C3 1 HETATM 7030 C C4 . NAG D 3 . ? 61.948 124.636 48.912 1.00 55.25 ? 2002 NAG A C4 1 HETATM 7031 C C5 . NAG D 3 . ? 63.068 124.350 47.900 1.00 53.97 ? 2002 NAG A C5 1 HETATM 7032 C C6 . NAG D 3 . ? 64.442 124.423 48.585 1.00 54.09 ? 2002 NAG A C6 1 HETATM 7033 C C7 . NAG D 3 . ? 60.522 120.056 49.826 1.00 57.37 ? 2002 NAG A C7 1 HETATM 7034 C C8 . NAG D 3 . ? 61.086 118.692 49.504 1.00 56.70 ? 2002 NAG A C8 1 HETATM 7035 N N2 . NAG D 3 . ? 60.539 121.017 48.902 1.00 56.07 ? 2002 NAG A N2 1 HETATM 7036 O O3 . NAG D 3 . ? 60.101 123.688 50.183 1.00 51.11 ? 2002 NAG A O3 1 HETATM 7037 O O4 . NAG D 3 . ? 61.377 125.896 48.584 1.00 57.64 ? 2002 NAG A O4 1 HETATM 7038 O O5 . NAG D 3 . ? 62.842 123.108 47.211 1.00 52.69 ? 2002 NAG A O5 1 HETATM 7039 O O6 . NAG D 3 . ? 65.387 125.202 47.870 1.00 51.28 ? 2002 NAG A O6 1 HETATM 7040 O O7 . NAG D 3 . ? 60.066 120.292 50.944 1.00 59.63 ? 2002 NAG A O7 1 HETATM 7041 C C1 . NAG E 3 . ? 21.066 99.378 19.258 1.00 30.80 ? 2003 NAG A C1 1 HETATM 7042 C C2 . NAG E 3 . ? 21.236 100.246 18.005 1.00 32.16 ? 2003 NAG A C2 1 HETATM 7043 C C3 . NAG E 3 . ? 20.636 101.657 18.187 1.00 32.81 ? 2003 NAG A C3 1 HETATM 7044 C C4 . NAG E 3 . ? 19.190 101.644 18.686 1.00 34.50 ? 2003 NAG A C4 1 HETATM 7045 C C5 . NAG E 3 . ? 19.115 100.675 19.874 1.00 33.30 ? 2003 NAG A C5 1 HETATM 7046 C C6 . NAG E 3 . ? 17.689 100.523 20.406 1.00 33.76 ? 2003 NAG A C6 1 HETATM 7047 C C7 . NAG E 3 . ? 23.142 99.616 16.570 1.00 32.28 ? 2003 NAG A C7 1 HETATM 7048 C C8 . NAG E 3 . ? 24.603 99.801 16.277 1.00 34.58 ? 2003 NAG A C8 1 HETATM 7049 N N2 . NAG E 3 . ? 22.642 100.314 17.587 1.00 33.26 ? 2003 NAG A N2 1 HETATM 7050 O O3 . NAG E 3 . ? 20.634 102.322 16.953 1.00 31.36 ? 2003 NAG A O3 1 HETATM 7051 O O4 . NAG E 3 . ? 18.788 102.952 19.105 1.00 37.94 ? 2003 NAG A O4 1 HETATM 7052 O O5 . NAG E 3 . ? 19.678 99.389 19.596 1.00 32.09 ? 2003 NAG A O5 1 HETATM 7053 O O6 . NAG E 3 . ? 17.708 99.754 21.592 1.00 34.81 ? 2003 NAG A O6 1 HETATM 7054 O O7 . NAG E 3 . ? 22.472 98.850 15.879 1.00 35.09 ? 2003 NAG A O7 1 HETATM 7055 C C1 . NAG F 3 . ? 18.197 103.788 18.102 1.00 43.26 ? 2004 NAG A C1 1 HETATM 7056 C C2 . NAG F 3 . ? 16.703 104.040 18.410 1.00 46.90 ? 2004 NAG A C2 1 HETATM 7057 C C3 . NAG F 3 . ? 16.130 105.002 17.387 1.00 48.24 ? 2004 NAG A C3 1 HETATM 7058 C C4 . NAG F 3 . ? 16.885 106.328 17.464 1.00 49.37 ? 2004 NAG A C4 1 HETATM 7059 C C5 . NAG F 3 . ? 18.382 106.076 17.229 1.00 47.38 ? 2004 NAG A C5 1 HETATM 7060 C C6 . NAG F 3 . ? 19.186 107.334 17.528 1.00 48.46 ? 2004 NAG A C6 1 HETATM 7061 C C7 . NAG F 3 . ? 15.044 102.509 19.431 1.00 49.17 ? 2004 NAG A C7 1 HETATM 7062 C C8 . NAG F 3 . ? 14.301 101.216 19.250 1.00 49.47 ? 2004 NAG A C8 1 HETATM 7063 N N2 . NAG F 3 . ? 15.859 102.851 18.423 1.00 47.99 ? 2004 NAG A N2 1 HETATM 7064 O O3 . NAG F 3 . ? 14.771 105.178 17.703 1.00 51.64 ? 2004 NAG A O3 1 HETATM 7065 O O4 . NAG F 3 . ? 16.340 107.285 16.551 1.00 52.64 ? 2004 NAG A O4 1 HETATM 7066 O O5 . NAG F 3 . ? 18.894 105.022 18.056 1.00 45.11 ? 2004 NAG A O5 1 HETATM 7067 O O6 . NAG F 3 . ? 20.521 107.149 17.093 1.00 46.92 ? 2004 NAG A O6 1 HETATM 7068 O O7 . NAG F 3 . ? 14.885 103.169 20.463 1.00 50.17 ? 2004 NAG A O7 1 HETATM 7069 C C1 . NAG G 3 . ? 51.026 77.306 26.610 1.00 53.59 ? 2005 NAG A C1 1 HETATM 7070 C C2 . NAG G 3 . ? 52.240 77.606 27.507 1.00 58.51 ? 2005 NAG A C2 1 HETATM 7071 C C3 . NAG G 3 . ? 52.193 76.824 28.821 1.00 60.77 ? 2005 NAG A C3 1 HETATM 7072 C C4 . NAG G 3 . ? 50.823 76.765 29.509 1.00 61.18 ? 2005 NAG A C4 1 HETATM 7073 C C5 . NAG G 3 . ? 49.587 76.896 28.623 1.00 60.73 ? 2005 NAG A C5 1 HETATM 7074 C C6 . NAG G 3 . ? 48.630 77.781 29.424 1.00 62.58 ? 2005 NAG A C6 1 HETATM 7075 C C7 . NAG G 3 . ? 54.629 78.037 26.929 1.00 59.25 ? 2005 NAG A C7 1 HETATM 7076 C C8 . NAG G 3 . ? 55.897 77.301 26.573 1.00 58.43 ? 2005 NAG A C8 1 HETATM 7077 N N2 . NAG G 3 . ? 53.495 77.324 26.813 1.00 58.59 ? 2005 NAG A N2 1 HETATM 7078 O O3 . NAG G 3 . ? 53.123 77.426 29.704 1.00 62.37 ? 2005 NAG A O3 1 HETATM 7079 O O4 . NAG G 3 . ? 50.694 75.554 30.225 1.00 63.34 ? 2005 NAG A O4 1 HETATM 7080 O O5 . NAG G 3 . ? 49.796 77.469 27.331 1.00 57.41 ? 2005 NAG A O5 1 HETATM 7081 O O6 . NAG G 3 . ? 47.290 77.456 29.123 1.00 65.58 ? 2005 NAG A O6 1 HETATM 7082 O O7 . NAG G 3 . ? 54.680 79.216 27.306 1.00 58.51 ? 2005 NAG A O7 1 HETATM 7083 O O . HOH H 4 . ? 43.935 101.488 20.614 1.00 17.17 ? 876 HOH A O 1 HETATM 7084 O O . HOH H 4 . ? 50.492 97.551 11.659 1.00 13.95 ? 877 HOH A O 1 HETATM 7085 O O . HOH H 4 . ? 59.902 110.249 45.023 1.00 18.27 ? 878 HOH A O 1 HETATM 7086 O O . HOH H 4 . ? 50.188 103.595 15.596 1.00 17.94 ? 879 HOH A O 1 HETATM 7087 O O . HOH H 4 . ? 57.794 99.549 31.626 1.00 15.15 ? 880 HOH A O 1 HETATM 7088 O O . HOH H 4 . ? 55.209 125.082 24.262 1.00 23.33 ? 881 HOH A O 1 HETATM 7089 O O . HOH H 4 . ? 65.229 110.302 16.005 1.00 16.71 ? 882 HOH A O 1 HETATM 7090 O O . HOH H 4 . ? 47.988 95.966 21.401 1.00 14.22 ? 883 HOH A O 1 HETATM 7091 O O . HOH H 4 . ? 66.021 115.743 34.364 1.00 17.58 ? 884 HOH A O 1 HETATM 7092 O O . HOH H 4 . ? 63.387 109.518 17.518 1.00 13.35 ? 885 HOH A O 1 HETATM 7093 O O . HOH H 4 . ? 51.004 106.142 15.500 1.00 21.66 ? 886 HOH A O 1 HETATM 7094 O O . HOH H 4 . ? 54.114 93.463 30.375 1.00 17.32 ? 887 HOH A O 1 HETATM 7095 O O . HOH H 4 . ? 36.239 81.794 6.974 1.00 17.45 ? 888 HOH A O 1 HETATM 7096 O O . HOH H 4 . ? 57.752 106.483 31.316 1.00 14.49 ? 889 HOH A O 1 HETATM 7097 O O . HOH H 4 . ? 49.925 85.184 -4.154 1.00 18.34 ? 890 HOH A O 1 HETATM 7098 O O . HOH H 4 . ? 67.846 103.586 9.558 1.00 14.65 ? 891 HOH A O 1 HETATM 7099 O O . HOH H 4 . ? 63.677 96.548 12.227 1.00 24.54 ? 892 HOH A O 1 HETATM 7100 O O . HOH H 4 . ? 64.803 103.347 -6.729 1.00 25.00 ? 893 HOH A O 1 HETATM 7101 O O . HOH H 4 . ? 54.293 91.945 18.169 1.00 15.29 ? 894 HOH A O 1 HETATM 7102 O O . HOH H 4 . ? 34.548 94.938 -2.846 1.00 26.37 ? 895 HOH A O 1 HETATM 7103 O O . HOH H 4 . ? 78.433 98.011 13.270 1.00 19.80 ? 896 HOH A O 1 HETATM 7104 O O . HOH H 4 . ? 52.276 85.494 21.084 1.00 16.35 ? 897 HOH A O 1 HETATM 7105 O O . HOH H 4 . ? 49.499 70.375 2.776 1.00 19.91 ? 898 HOH A O 1 HETATM 7106 O O . HOH H 4 . ? 38.584 95.286 4.567 1.00 15.53 ? 899 HOH A O 1 HETATM 7107 O O . HOH H 4 . ? 58.513 84.024 12.630 1.00 19.76 ? 900 HOH A O 1 HETATM 7108 O O . HOH H 4 . ? 59.925 91.161 14.636 1.00 16.28 ? 901 HOH A O 1 HETATM 7109 O O . HOH H 4 . ? 69.715 94.918 15.752 1.00 20.38 ? 902 HOH A O 1 HETATM 7110 O O . HOH H 4 . ? 53.486 98.420 32.458 1.00 18.86 ? 903 HOH A O 1 HETATM 7111 O O . HOH H 4 . ? 33.774 90.829 5.351 1.00 20.41 ? 904 HOH A O 1 HETATM 7112 O O . HOH H 4 . ? 57.757 91.018 29.494 1.00 19.35 ? 905 HOH A O 1 HETATM 7113 O O . HOH H 4 . ? 53.878 95.586 43.947 1.00 19.42 ? 906 HOH A O 1 HETATM 7114 O O . HOH H 4 . ? 41.901 97.802 18.520 1.00 15.45 ? 907 HOH A O 1 HETATM 7115 O O . HOH H 4 . ? 30.623 99.189 35.789 1.00 21.50 ? 908 HOH A O 1 HETATM 7116 O O . HOH H 4 . ? 47.070 96.488 11.698 1.00 21.94 ? 909 HOH A O 1 HETATM 7117 O O . HOH H 4 . ? 72.043 91.931 26.646 1.00 20.84 ? 910 HOH A O 1 HETATM 7118 O O . HOH H 4 . ? 45.469 78.332 1.770 1.00 17.72 ? 911 HOH A O 1 HETATM 7119 O O . HOH H 4 . ? 40.141 97.617 4.451 1.00 18.58 ? 912 HOH A O 1 HETATM 7120 O O . HOH H 4 . ? 53.501 97.432 45.895 1.00 20.78 ? 913 HOH A O 1 HETATM 7121 O O . HOH H 4 . ? 36.569 97.880 43.269 1.00 25.24 ? 914 HOH A O 1 HETATM 7122 O O . HOH H 4 . ? 52.428 76.433 -4.466 1.00 25.62 ? 915 HOH A O 1 HETATM 7123 O O . HOH H 4 . ? 66.805 110.750 43.809 1.00 27.54 ? 916 HOH A O 1 HETATM 7124 O O . HOH H 4 . ? 51.155 111.595 27.226 1.00 17.85 ? 917 HOH A O 1 HETATM 7125 O O . HOH H 4 . ? 65.957 89.968 24.569 1.00 23.98 ? 918 HOH A O 1 HETATM 7126 O O . HOH H 4 . ? 75.814 99.308 26.368 1.00 18.17 ? 919 HOH A O 1 HETATM 7127 O O . HOH H 4 . ? 46.074 89.574 17.979 1.00 19.67 ? 920 HOH A O 1 HETATM 7128 O O . HOH H 4 . ? 50.711 100.764 13.458 1.00 13.84 ? 921 HOH A O 1 HETATM 7129 O O . HOH H 4 . ? 49.373 117.081 29.379 1.00 21.31 ? 922 HOH A O 1 HETATM 7130 O O . HOH H 4 . ? 35.684 93.618 20.182 1.00 23.92 ? 923 HOH A O 1 HETATM 7131 O O . HOH H 4 . ? 53.211 99.254 43.838 1.00 18.14 ? 924 HOH A O 1 HETATM 7132 O O . HOH H 4 . ? 38.780 94.321 6.967 1.00 19.23 ? 925 HOH A O 1 HETATM 7133 O O . HOH H 4 . ? 59.160 88.923 21.950 1.00 13.64 ? 926 HOH A O 1 HETATM 7134 O O . HOH H 4 . ? 46.420 89.190 38.850 1.00 14.92 ? 927 HOH A O 1 HETATM 7135 O O . HOH H 4 . ? 71.009 115.046 20.246 1.00 17.53 ? 928 HOH A O 1 HETATM 7136 O O . HOH H 4 . ? 54.137 107.078 3.145 1.00 17.48 ? 929 HOH A O 1 HETATM 7137 O O . HOH H 4 . ? 55.685 112.118 -3.968 1.00 27.40 ? 930 HOH A O 1 HETATM 7138 O O . HOH H 4 . ? 54.300 90.169 40.005 1.00 15.63 ? 931 HOH A O 1 HETATM 7139 O O . HOH H 4 . ? 51.382 83.822 23.418 1.00 24.51 ? 932 HOH A O 1 HETATM 7140 O O . HOH H 4 . ? 54.293 97.253 41.785 1.00 18.06 ? 933 HOH A O 1 HETATM 7141 O O . HOH H 4 . ? 58.609 111.667 43.591 1.00 23.08 ? 934 HOH A O 1 HETATM 7142 O O . HOH H 4 . ? 45.834 60.543 1.769 1.00 40.20 ? 935 HOH A O 1 HETATM 7143 O O . HOH H 4 . ? 49.459 103.897 -21.285 1.00 28.09 ? 936 HOH A O 1 HETATM 7144 O O . HOH H 4 . ? 56.495 110.186 9.109 1.00 19.84 ? 937 HOH A O 1 HETATM 7145 O O . HOH H 4 . ? 56.423 90.226 43.398 1.00 23.56 ? 938 HOH A O 1 HETATM 7146 O O . HOH H 4 . ? 71.950 94.809 33.464 1.00 23.32 ? 939 HOH A O 1 HETATM 7147 O O . HOH H 4 . ? 66.351 103.165 -4.784 1.00 20.21 ? 940 HOH A O 1 HETATM 7148 O O . HOH H 4 . ? 45.096 105.486 0.624 1.00 24.68 ? 941 HOH A O 1 HETATM 7149 O O . HOH H 4 . ? 69.379 94.277 33.318 1.00 17.26 ? 942 HOH A O 1 HETATM 7150 O O . HOH H 4 . ? 64.086 117.038 33.269 1.00 19.95 ? 943 HOH A O 1 HETATM 7151 O O . HOH H 4 . ? 87.111 98.363 26.540 1.00 45.51 ? 944 HOH A O 1 HETATM 7152 O O . HOH H 4 . ? 64.267 121.017 40.571 1.00 29.79 ? 945 HOH A O 1 HETATM 7153 O O . HOH H 4 . ? 39.847 97.810 -6.485 1.00 18.49 ? 946 HOH A O 1 HETATM 7154 O O . HOH H 4 . ? 39.553 101.837 4.032 1.00 21.14 ? 947 HOH A O 1 HETATM 7155 O O . HOH H 4 . ? 53.657 78.206 13.478 1.00 23.71 ? 948 HOH A O 1 HETATM 7156 O O . HOH H 4 . ? 52.533 77.834 2.699 1.00 15.51 ? 949 HOH A O 1 HETATM 7157 O O . HOH H 4 . ? 41.364 83.820 20.477 1.00 17.74 ? 950 HOH A O 1 HETATM 7158 O O . HOH H 4 . ? 35.861 94.230 28.723 1.00 22.63 ? 951 HOH A O 1 HETATM 7159 O O . HOH H 4 . ? 67.390 107.431 7.751 1.00 26.30 ? 952 HOH A O 1 HETATM 7160 O O . HOH H 4 . ? 57.283 90.190 20.413 1.00 18.85 ? 953 HOH A O 1 HETATM 7161 O O . HOH H 4 . ? 36.786 88.149 11.044 1.00 24.98 ? 954 HOH A O 1 HETATM 7162 O O . HOH H 4 . ? 34.593 80.824 15.377 1.00 24.94 ? 955 HOH A O 1 HETATM 7163 O O . HOH H 4 . ? 68.595 95.908 18.718 1.00 21.30 ? 956 HOH A O 1 HETATM 7164 O O . HOH H 4 . ? 48.519 79.126 1.855 1.00 17.96 ? 957 HOH A O 1 HETATM 7165 O O . HOH H 4 . ? 54.441 78.273 7.006 1.00 28.75 ? 958 HOH A O 1 HETATM 7166 O O . HOH H 4 . ? 53.981 82.139 2.752 1.00 23.24 ? 959 HOH A O 1 HETATM 7167 O O . HOH H 4 . ? 25.790 98.421 39.267 1.00 35.56 ? 960 HOH A O 1 HETATM 7168 O O . HOH H 4 . ? 51.723 96.401 47.648 1.00 19.89 ? 961 HOH A O 1 HETATM 7169 O O . HOH H 4 . ? 43.198 60.276 1.004 1.00 38.12 ? 962 HOH A O 1 HETATM 7170 O O . HOH H 4 . ? 78.082 99.362 10.803 1.00 18.33 ? 963 HOH A O 1 HETATM 7171 O O . HOH H 4 . ? 43.541 102.090 3.059 1.00 18.10 ? 964 HOH A O 1 HETATM 7172 O O . HOH H 4 . ? 60.419 120.566 27.247 1.00 29.42 ? 965 HOH A O 1 HETATM 7173 O O . HOH H 4 . ? 90.734 116.446 21.001 1.00 30.07 ? 966 HOH A O 1 HETATM 7174 O O . HOH H 4 . ? 58.612 123.292 33.433 1.00 18.82 ? 967 HOH A O 1 HETATM 7175 O O . HOH H 4 . ? 57.396 131.696 24.824 1.00 27.84 ? 968 HOH A O 1 HETATM 7176 O O . HOH H 4 . ? 52.615 91.779 24.190 1.00 26.09 ? 969 HOH A O 1 HETATM 7177 O O . HOH H 4 . ? 47.202 80.597 19.016 1.00 27.86 ? 970 HOH A O 1 HETATM 7178 O O . HOH H 4 . ? 27.148 110.144 30.474 1.00 27.53 ? 971 HOH A O 1 HETATM 7179 O O . HOH H 4 . ? 46.337 107.052 13.421 1.00 18.69 ? 972 HOH A O 1 HETATM 7180 O O . HOH H 4 . ? 58.071 122.239 35.632 1.00 23.82 ? 973 HOH A O 1 HETATM 7181 O O . HOH H 4 . ? 60.800 89.861 -3.385 1.00 22.20 ? 974 HOH A O 1 HETATM 7182 O O . HOH H 4 . ? 66.443 88.636 16.305 1.00 22.51 ? 975 HOH A O 1 HETATM 7183 O O . HOH H 4 . ? 35.102 97.420 35.488 1.00 21.86 ? 976 HOH A O 1 HETATM 7184 O O . HOH H 4 . ? 33.828 100.106 19.986 1.00 21.25 ? 977 HOH A O 1 HETATM 7185 O O . HOH H 4 . ? 68.144 96.258 -2.508 1.00 28.17 ? 978 HOH A O 1 HETATM 7186 O O . HOH H 4 . ? 52.320 118.456 37.997 1.00 38.60 ? 979 HOH A O 1 HETATM 7187 O O . HOH H 4 . ? 67.400 111.768 16.198 1.00 19.91 ? 980 HOH A O 1 HETATM 7188 O O . HOH H 4 . ? 53.986 91.429 28.186 1.00 18.45 ? 981 HOH A O 1 HETATM 7189 O O . HOH H 4 . ? 40.121 95.397 19.707 1.00 16.93 ? 982 HOH A O 1 HETATM 7190 O O . HOH H 4 . ? 66.837 86.445 43.743 1.00 30.20 ? 983 HOH A O 1 HETATM 7191 O O . HOH H 4 . ? 65.210 90.809 -7.086 1.00 24.46 ? 984 HOH A O 1 HETATM 7192 O O . HOH H 4 . ? 48.869 80.483 25.691 1.00 35.63 ? 985 HOH A O 1 HETATM 7193 O O . HOH H 4 . ? 50.690 111.851 11.031 1.00 23.30 ? 986 HOH A O 1 HETATM 7194 O O . HOH H 4 . ? 54.821 117.535 31.737 1.00 32.93 ? 987 HOH A O 1 HETATM 7195 O O . HOH H 4 . ? 60.948 124.439 33.042 1.00 17.93 ? 988 HOH A O 1 HETATM 7196 O O . HOH H 4 . ? 76.875 101.171 33.400 1.00 33.93 ? 989 HOH A O 1 HETATM 7197 O O . HOH H 4 . ? 32.954 99.068 34.760 1.00 20.13 ? 990 HOH A O 1 HETATM 7198 O O . HOH H 4 . ? 56.111 87.786 27.956 1.00 27.26 ? 991 HOH A O 1 HETATM 7199 O O . HOH H 4 . ? 79.052 106.400 14.238 1.00 24.61 ? 992 HOH A O 1 HETATM 7200 O O . HOH H 4 . ? 66.814 112.621 41.996 1.00 28.55 ? 993 HOH A O 1 HETATM 7201 O O . HOH H 4 . ? 65.397 105.487 -8.182 1.00 34.65 ? 994 HOH A O 1 HETATM 7202 O O . HOH H 4 . ? 61.076 111.744 46.988 1.00 23.78 ? 995 HOH A O 1 HETATM 7203 O O . HOH H 4 . ? 72.591 118.020 33.538 1.00 25.86 ? 996 HOH A O 1 HETATM 7204 O O . HOH H 4 . ? 62.499 82.460 35.215 1.00 31.78 ? 997 HOH A O 1 HETATM 7205 O O . HOH H 4 . ? 55.300 101.012 -12.819 1.00 21.87 ? 998 HOH A O 1 HETATM 7206 O O . HOH H 4 . ? 52.597 76.882 5.162 1.00 22.19 ? 999 HOH A O 1 HETATM 7207 O O . HOH H 4 . ? 70.906 103.024 1.615 1.00 26.21 ? 1000 HOH A O 1 HETATM 7208 O O . HOH H 4 . ? 46.040 88.739 29.562 1.00 22.24 ? 1002 HOH A O 1 HETATM 7209 O O . HOH H 4 . ? 59.659 65.281 7.589 1.00 53.25 ? 1003 HOH A O 1 HETATM 7210 O O . HOH H 4 . ? 50.097 77.102 5.604 1.00 27.93 ? 1004 HOH A O 1 HETATM 7211 O O . HOH H 4 . ? 31.042 81.274 28.460 1.00 26.18 ? 1005 HOH A O 1 HETATM 7212 O O . HOH H 4 . ? 26.336 95.725 24.867 1.00 21.05 ? 1006 HOH A O 1 HETATM 7213 O O . HOH H 4 . ? 56.221 117.640 34.464 1.00 30.48 ? 1007 HOH A O 1 HETATM 7214 O O . HOH H 4 . ? 55.709 83.194 22.084 1.00 25.06 ? 1008 HOH A O 1 HETATM 7215 O O . HOH H 4 . ? 46.241 74.429 -7.506 1.00 40.60 ? 1009 HOH A O 1 HETATM 7216 O O . HOH H 4 . ? 54.077 83.338 42.895 1.00 35.85 ? 1010 HOH A O 1 HETATM 7217 O O . HOH H 4 . ? 30.378 94.944 8.912 1.00 22.49 ? 1011 HOH A O 1 HETATM 7218 O O . HOH H 4 . ? 81.615 106.942 16.245 1.00 28.78 ? 1012 HOH A O 1 HETATM 7219 O O . HOH H 4 . ? 46.577 115.738 32.588 1.00 23.86 ? 1013 HOH A O 1 HETATM 7220 O O . HOH H 4 . ? 64.035 104.305 -1.412 1.00 23.79 ? 1014 HOH A O 1 HETATM 7221 O O . HOH H 4 . ? 45.877 109.157 3.624 1.00 24.93 ? 1015 HOH A O 1 HETATM 7222 O O . HOH H 4 . ? 68.802 115.165 21.677 1.00 19.84 ? 1016 HOH A O 1 HETATM 7223 O O . HOH H 4 . ? 48.630 83.125 25.049 1.00 30.83 ? 1017 HOH A O 1 HETATM 7224 O O . HOH H 4 . ? 82.645 99.841 29.114 1.00 46.40 ? 1018 HOH A O 1 HETATM 7225 O O . HOH H 4 . ? 33.020 88.238 4.888 1.00 21.23 ? 1019 HOH A O 1 HETATM 7226 O O . HOH H 4 . ? 43.477 92.463 11.388 1.00 27.64 ? 1020 HOH A O 1 HETATM 7227 O O . HOH H 4 . ? 58.402 103.566 -12.284 1.00 43.61 ? 1021 HOH A O 1 HETATM 7228 O O . HOH H 4 . ? 48.516 82.871 -1.845 1.00 17.59 ? 1022 HOH A O 1 HETATM 7229 O O . HOH H 4 . ? 49.316 77.974 8.411 1.00 21.37 ? 1023 HOH A O 1 HETATM 7230 O O . HOH H 4 . ? 68.902 87.789 45.198 1.00 33.56 ? 1024 HOH A O 1 HETATM 7231 O O . HOH H 4 . ? 45.890 77.687 10.186 1.00 36.94 ? 1025 HOH A O 1 HETATM 7232 O O . HOH H 4 . ? 55.939 109.300 0.795 1.00 23.38 ? 1026 HOH A O 1 HETATM 7233 O O . HOH H 4 . ? 50.340 112.749 15.968 1.00 29.17 ? 1027 HOH A O 1 HETATM 7234 O O . HOH H 4 . ? 45.456 99.935 42.466 1.00 26.17 ? 1028 HOH A O 1 HETATM 7235 O O . HOH H 4 . ? 47.727 109.444 5.595 1.00 21.81 ? 1029 HOH A O 1 HETATM 7236 O O . HOH H 4 . ? 57.176 113.417 45.035 1.00 23.79 ? 1030 HOH A O 1 HETATM 7237 O O . HOH H 4 . ? 73.975 105.083 11.563 1.00 23.54 ? 1031 HOH A O 1 HETATM 7238 O O . HOH H 4 . ? 66.099 93.267 48.939 1.00 30.73 ? 1032 HOH A O 1 HETATM 7239 O O . HOH H 4 . ? 58.229 125.006 30.447 1.00 23.31 ? 1033 HOH A O 1 HETATM 7240 O O . HOH H 4 . ? 72.610 88.435 29.592 1.00 24.30 ? 1034 HOH A O 1 HETATM 7241 O O . HOH H 4 . ? 61.658 103.983 52.037 1.00 31.46 ? 1035 HOH A O 1 HETATM 7242 O O . HOH H 4 . ? 64.290 129.424 29.735 1.00 34.34 ? 1036 HOH A O 1 HETATM 7243 O O . HOH H 4 . ? 62.560 81.717 32.711 1.00 28.69 ? 1037 HOH A O 1 HETATM 7244 O O . HOH H 4 . ? 35.383 95.903 30.770 1.00 23.22 ? 1038 HOH A O 1 HETATM 7245 O O . HOH H 4 . ? 54.892 91.624 50.105 1.00 28.17 ? 1039 HOH A O 1 HETATM 7246 O O . HOH H 4 . ? 40.827 95.929 34.090 1.00 23.69 ? 1040 HOH A O 1 HETATM 7247 O O . HOH H 4 . ? 49.282 93.921 32.927 1.00 21.49 ? 1041 HOH A O 1 HETATM 7248 O O . HOH H 4 . ? 50.181 111.531 8.345 1.00 17.74 ? 1042 HOH A O 1 HETATM 7249 O O . HOH H 4 . ? 55.956 120.394 34.194 1.00 30.98 ? 1043 HOH A O 1 HETATM 7250 O O . HOH H 4 . ? 71.016 130.726 15.933 1.00 37.23 ? 1044 HOH A O 1 HETATM 7251 O O . HOH H 4 . ? 50.847 80.067 2.481 1.00 23.21 ? 1045 HOH A O 1 HETATM 7252 O O . HOH H 4 . ? 71.815 88.586 36.810 1.00 36.85 ? 1046 HOH A O 1 HETATM 7253 O O . HOH H 4 . ? 67.456 91.540 15.272 1.00 43.05 ? 1047 HOH A O 1 HETATM 7254 O O . HOH H 4 . ? 80.190 98.616 9.534 1.00 26.95 ? 1048 HOH A O 1 HETATM 7255 O O . HOH H 4 . ? 76.141 89.501 16.658 1.00 31.91 ? 1049 HOH A O 1 HETATM 7256 O O . HOH H 4 . ? 68.340 82.982 32.842 1.00 26.88 ? 1050 HOH A O 1 HETATM 7257 O O . HOH H 4 . ? 86.785 109.858 26.834 1.00 25.29 ? 1051 HOH A O 1 HETATM 7258 O O . HOH H 4 . ? 54.314 85.401 30.258 1.00 24.14 ? 1052 HOH A O 1 HETATM 7259 O O . HOH H 4 . ? 71.774 127.948 24.255 1.00 25.63 ? 1053 HOH A O 1 HETATM 7260 O O . HOH H 4 . ? 38.685 85.009 20.538 1.00 25.88 ? 1054 HOH A O 1 HETATM 7261 O O . HOH H 4 . ? 39.128 88.035 21.694 1.00 37.85 ? 1055 HOH A O 1 HETATM 7262 O O . HOH H 4 . ? 30.383 90.673 2.222 1.00 34.24 ? 1056 HOH A O 1 HETATM 7263 O O . HOH H 4 . ? 42.947 66.737 4.234 1.00 19.01 ? 1057 HOH A O 1 HETATM 7264 O O . HOH H 4 . ? 36.268 104.818 36.434 1.00 27.32 ? 1058 HOH A O 1 HETATM 7265 O O . HOH H 4 . ? 39.352 87.812 40.065 1.00 36.43 ? 1059 HOH A O 1 HETATM 7266 O O . HOH H 4 . ? 57.584 105.104 16.641 1.00 22.78 ? 1060 HOH A O 1 HETATM 7267 O O . HOH H 4 . ? 49.013 117.004 31.944 1.00 26.39 ? 1061 HOH A O 1 HETATM 7268 O O . HOH H 4 . ? 68.150 94.090 46.987 1.00 22.22 ? 1062 HOH A O 1 HETATM 7269 O O . HOH H 4 . ? 39.425 88.580 24.442 1.00 16.27 ? 1063 HOH A O 1 HETATM 7270 O O . HOH H 4 . ? 61.382 122.172 13.487 1.00 34.53 ? 1064 HOH A O 1 HETATM 7271 O O . HOH H 4 . ? 41.765 103.204 53.205 1.00 30.16 ? 1065 HOH A O 1 HETATM 7272 O O . HOH H 4 . ? 88.997 107.247 27.073 1.00 26.47 ? 1066 HOH A O 1 HETATM 7273 O O . HOH H 4 . ? 57.114 90.986 24.623 1.00 23.84 ? 1067 HOH A O 1 HETATM 7274 O O . HOH H 4 . ? 40.141 99.434 2.790 1.00 24.12 ? 1068 HOH A O 1 HETATM 7275 O O . HOH H 4 . ? 95.708 116.559 25.895 1.00 29.21 ? 1069 HOH A O 1 HETATM 7276 O O . HOH H 4 . ? 26.981 94.259 37.024 1.00 32.41 ? 1070 HOH A O 1 HETATM 7277 O O . HOH H 4 . ? 41.775 94.475 -17.232 1.00 28.09 ? 1071 HOH A O 1 HETATM 7278 O O . HOH H 4 . ? 69.824 126.681 23.494 1.00 28.93 ? 1072 HOH A O 1 HETATM 7279 O O . HOH H 4 . ? 41.590 77.433 14.794 1.00 29.66 ? 1073 HOH A O 1 HETATM 7280 O O . HOH H 4 . ? 51.042 112.027 -5.819 1.00 36.53 ? 1074 HOH A O 1 HETATM 7281 O O . HOH H 4 . ? 64.525 92.616 -11.339 1.00 47.52 ? 1075 HOH A O 1 HETATM 7282 O O . HOH H 4 . ? 49.868 97.193 49.184 1.00 31.37 ? 1076 HOH A O 1 HETATM 7283 O O . HOH H 4 . ? 32.261 92.272 3.489 1.00 21.81 ? 1077 HOH A O 1 HETATM 7284 O O . HOH H 4 . ? 34.792 97.184 -1.351 1.00 33.25 ? 1078 HOH A O 1 HETATM 7285 O O . HOH H 4 . ? 62.213 99.955 16.724 1.00 26.34 ? 1079 HOH A O 1 HETATM 7286 O O . HOH H 4 . ? 62.001 110.464 -5.739 1.00 36.18 ? 1080 HOH A O 1 HETATM 7287 O O . HOH H 4 . ? 19.530 98.876 14.781 1.00 48.91 ? 1081 HOH A O 1 HETATM 7288 O O . HOH H 4 . ? 42.931 117.724 25.323 1.00 24.27 ? 1082 HOH A O 1 HETATM 7289 O O . HOH H 4 . ? 53.048 126.503 25.001 1.00 33.17 ? 1083 HOH A O 1 HETATM 7290 O O . HOH H 4 . ? 74.030 92.696 1.691 1.00 32.28 ? 1084 HOH A O 1 HETATM 7291 O O . HOH H 4 . ? 41.434 88.790 39.160 1.00 27.72 ? 1085 HOH A O 1 HETATM 7292 O O . HOH H 4 . ? 63.951 104.999 52.389 1.00 31.89 ? 1086 HOH A O 1 HETATM 7293 O O . HOH H 4 . ? 30.570 109.482 35.670 1.00 23.83 ? 1087 HOH A O 1 HETATM 7294 O O . HOH H 4 . ? 31.683 107.045 43.925 1.00 31.62 ? 1088 HOH A O 1 HETATM 7295 O O . HOH H 4 . ? 61.052 116.788 42.898 1.00 26.02 ? 1089 HOH A O 1 HETATM 7296 O O . HOH H 4 . ? 44.275 77.166 21.195 1.00 30.43 ? 1090 HOH A O 1 HETATM 7297 O O . HOH H 4 . ? 35.329 116.296 24.048 1.00 33.93 ? 1091 HOH A O 1 HETATM 7298 O O . HOH H 4 . ? 70.260 134.158 19.780 1.00 50.97 ? 1092 HOH A O 1 HETATM 7299 O O . HOH H 4 . ? 78.800 125.820 36.311 1.00 33.57 ? 1093 HOH A O 1 HETATM 7300 O O . HOH H 4 . ? 70.922 113.230 18.322 1.00 24.99 ? 1094 HOH A O 1 HETATM 7301 O O . HOH H 4 . ? 85.210 121.892 35.749 1.00 28.33 ? 1095 HOH A O 1 HETATM 7302 O O . HOH H 4 . ? 43.227 77.493 16.899 1.00 31.43 ? 1096 HOH A O 1 HETATM 7303 O O . HOH H 4 . ? 34.458 96.101 33.461 1.00 27.97 ? 1097 HOH A O 1 HETATM 7304 O O . HOH H 4 . ? 54.959 78.570 -5.620 1.00 27.98 ? 1098 HOH A O 1 HETATM 7305 O O . HOH H 4 . ? 54.919 111.622 1.545 1.00 33.30 ? 1099 HOH A O 1 HETATM 7306 O O . HOH H 4 . ? 47.716 112.628 24.221 1.00 35.89 ? 1100 HOH A O 1 HETATM 7307 O O . HOH H 4 . ? 32.812 114.762 23.463 1.00 36.97 ? 1101 HOH A O 1 HETATM 7308 O O . HOH H 4 . ? 39.996 111.621 19.113 1.00 28.62 ? 1102 HOH A O 1 HETATM 7309 O O . HOH H 4 . ? 30.040 95.213 41.092 1.00 28.23 ? 1103 HOH A O 1 HETATM 7310 O O . HOH H 4 . ? 24.553 88.537 18.579 1.00 25.39 ? 1104 HOH A O 1 HETATM 7311 O O . HOH H 4 . ? 60.175 84.960 14.987 1.00 33.95 ? 1105 HOH A O 1 HETATM 7312 O O . HOH H 4 . ? 55.047 127.915 29.683 1.00 31.04 ? 1106 HOH A O 1 HETATM 7313 O O . HOH H 4 . ? 38.968 101.762 -9.082 1.00 38.32 ? 1107 HOH A O 1 HETATM 7314 O O . HOH H 4 . ? 55.007 91.528 23.016 1.00 27.80 ? 1108 HOH A O 1 HETATM 7315 O O . HOH H 4 . ? 79.941 97.523 40.425 1.00 43.95 ? 1109 HOH A O 1 HETATM 7316 O O . HOH H 4 . ? 39.292 76.257 10.118 1.00 28.86 ? 1110 HOH A O 1 HETATM 7317 O O . HOH H 4 . ? 39.224 76.107 14.776 1.00 32.15 ? 1111 HOH A O 1 HETATM 7318 O O . HOH H 4 . ? 52.943 77.352 9.704 1.00 22.10 ? 1112 HOH A O 1 HETATM 7319 O O . HOH H 4 . ? 49.483 86.249 -7.720 1.00 27.71 ? 1113 HOH A O 1 HETATM 7320 O O . HOH H 4 . ? 44.283 118.044 43.415 1.00 26.95 ? 1114 HOH A O 1 HETATM 7321 O O . HOH H 4 . ? 42.597 110.129 -8.824 1.00 31.99 ? 1115 HOH A O 1 HETATM 7322 O O . HOH H 4 . ? 38.783 99.863 55.113 1.00 36.31 ? 1116 HOH A O 1 HETATM 7323 O O . HOH H 4 . ? 22.418 91.182 40.634 1.00 39.69 ? 1117 HOH A O 1 HETATM 7324 O O . HOH H 4 . ? 56.049 81.548 41.701 1.00 38.36 ? 1118 HOH A O 1 HETATM 7325 O O . HOH H 4 . ? 47.157 92.127 46.402 1.00 23.74 ? 1119 HOH A O 1 HETATM 7326 O O . HOH H 4 . ? 30.914 116.804 28.486 1.00 49.06 ? 1120 HOH A O 1 HETATM 7327 O O . HOH H 4 . ? 49.597 111.213 4.586 1.00 32.98 ? 1121 HOH A O 1 HETATM 7328 O O . HOH H 4 . ? 70.950 105.299 44.567 1.00 30.12 ? 1122 HOH A O 1 HETATM 7329 O O . HOH H 4 . ? 61.540 130.864 14.927 1.00 36.64 ? 1123 HOH A O 1 HETATM 7330 O O . HOH H 4 . ? 80.451 113.897 13.879 1.00 28.48 ? 1124 HOH A O 1 HETATM 7331 O O . HOH H 4 . ? 33.737 112.668 46.560 1.00 35.63 ? 1125 HOH A O 1 HETATM 7332 O O . HOH H 4 . ? 35.413 90.738 39.575 1.00 49.41 ? 1126 HOH A O 1 HETATM 7333 O O . HOH H 4 . ? 81.217 97.513 30.394 1.00 48.27 ? 1127 HOH A O 1 HETATM 7334 O O . HOH H 4 . ? 65.756 108.400 12.457 1.00 30.92 ? 1128 HOH A O 1 HETATM 7335 O O . HOH H 4 . ? 32.326 71.204 -6.455 1.00 32.97 ? 1129 HOH A O 1 HETATM 7336 O O . HOH H 4 . ? 61.056 116.878 12.737 1.00 25.20 ? 1130 HOH A O 1 HETATM 7337 O O . HOH H 4 . ? 83.195 89.275 16.852 1.00 35.01 ? 1131 HOH A O 1 HETATM 7338 O O . HOH H 4 . ? 73.581 91.350 22.011 1.00 34.27 ? 1132 HOH A O 1 HETATM 7339 O O . HOH H 4 . ? 29.869 91.715 -0.792 1.00 24.86 ? 1133 HOH A O 1 HETATM 7340 O O . HOH H 4 . ? 63.252 99.536 54.751 1.00 38.35 ? 1134 HOH A O 1 HETATM 7341 O O . HOH H 4 . ? 22.721 89.258 25.439 1.00 35.53 ? 1135 HOH A O 1 HETATM 7342 O O . HOH H 4 . ? 73.596 100.729 40.360 1.00 29.59 ? 1136 HOH A O 1 HETATM 7343 O O . HOH H 4 . ? 48.442 114.391 22.422 1.00 40.75 ? 1137 HOH A O 1 HETATM 7344 O O . HOH H 4 . ? 53.320 106.126 21.747 1.00 29.56 ? 1138 HOH A O 1 HETATM 7345 O O . HOH H 4 . ? 85.137 89.779 25.265 1.00 49.75 ? 1139 HOH A O 1 HETATM 7346 O O . HOH H 4 . ? 76.364 91.650 3.824 1.00 35.98 ? 1140 HOH A O 1 HETATM 7347 O O . HOH H 4 . ? 50.300 115.056 20.508 1.00 33.11 ? 1141 HOH A O 1 HETATM 7348 O O . HOH H 4 . ? 81.158 123.999 15.237 1.00 39.72 ? 1142 HOH A O 1 HETATM 7349 O O . HOH H 4 . ? 62.006 73.520 5.065 1.00 31.60 ? 1143 HOH A O 1 HETATM 7350 O O . HOH H 4 . ? 63.766 130.404 23.741 1.00 45.51 ? 1144 HOH A O 1 HETATM 7351 O O . HOH H 4 . ? 31.714 90.124 -2.240 1.00 24.14 ? 1145 HOH A O 1 HETATM 7352 O O . HOH H 4 . ? 32.691 99.360 4.608 1.00 33.91 ? 1146 HOH A O 1 HETATM 7353 O O . HOH H 4 . ? 36.799 84.071 31.781 1.00 56.38 ? 1147 HOH A O 1 HETATM 7354 O O . HOH H 4 . ? 57.748 112.487 -2.145 1.00 49.85 ? 1148 HOH A O 1 HETATM 7355 O O . HOH H 4 . ? 60.318 87.674 15.128 1.00 31.81 ? 1149 HOH A O 1 HETATM 7356 O O . HOH H 4 . ? 64.261 83.223 26.537 1.00 42.99 ? 1150 HOH A O 1 HETATM 7357 O O . HOH H 4 . ? 35.088 79.539 23.010 1.00 34.24 ? 1151 HOH A O 1 HETATM 7358 O O . HOH H 4 . ? 60.779 116.705 10.071 1.00 39.03 ? 1152 HOH A O 1 HETATM 7359 O O . HOH H 4 . ? 78.758 85.825 35.306 1.00 38.72 ? 1153 HOH A O 1 HETATM 7360 O O . HOH H 4 . ? 21.075 90.900 24.025 1.00 31.84 ? 1154 HOH A O 1 HETATM 7361 O O . HOH H 4 . ? 20.057 93.992 27.106 1.00 41.10 ? 1155 HOH A O 1 HETATM 7362 O O . HOH H 4 . ? 47.449 109.477 -0.219 1.00 44.54 ? 1156 HOH A O 1 HETATM 7363 O O . HOH H 4 . ? 52.854 111.771 47.331 1.00 30.29 ? 1157 HOH A O 1 HETATM 7364 O O . HOH H 4 . ? 56.665 125.116 32.369 1.00 32.87 ? 1158 HOH A O 1 HETATM 7365 O O . HOH H 4 . ? 30.327 87.334 5.055 1.00 37.38 ? 1159 HOH A O 1 HETATM 7366 O O . HOH H 4 . ? 64.221 75.072 5.635 1.00 35.49 ? 1160 HOH A O 1 HETATM 7367 O O . HOH H 4 . ? 53.054 74.245 5.826 1.00 24.77 ? 1161 HOH A O 1 HETATM 7368 O O . HOH H 4 . ? 53.328 96.642 52.039 1.00 41.26 ? 1162 HOH A O 1 HETATM 7369 O O . HOH H 4 . ? 65.927 108.948 9.048 1.00 46.01 ? 1163 HOH A O 1 HETATM 7370 O O . HOH H 4 . ? 67.286 113.305 20.630 1.00 27.22 ? 1164 HOH A O 1 HETATM 7371 O O . HOH H 4 . ? 61.484 84.135 -2.387 1.00 32.04 ? 1165 HOH A O 1 HETATM 7372 O O . HOH H 4 . ? 31.633 78.813 26.014 1.00 32.43 ? 1166 HOH A O 1 HETATM 7373 O O . HOH H 4 . ? 45.684 111.416 22.932 1.00 22.34 ? 1167 HOH A O 1 HETATM 7374 O O . HOH H 4 . ? 72.894 113.264 36.500 1.00 37.71 ? 1168 HOH A O 1 HETATM 7375 O O . HOH H 4 . ? 51.343 82.561 43.055 1.00 51.37 ? 1169 HOH A O 1 HETATM 7376 O O . HOH H 4 . ? 45.910 112.495 -2.235 1.00 49.48 ? 1170 HOH A O 1 HETATM 7377 O O . HOH H 4 . ? 60.292 104.370 54.376 1.00 40.66 ? 1171 HOH A O 1 HETATM 7378 O O . HOH H 4 . ? 25.830 102.433 18.443 1.00 27.49 ? 1172 HOH A O 1 HETATM 7379 O O . HOH H 4 . ? 71.947 97.567 -5.239 1.00 44.30 ? 1173 HOH A O 1 HETATM 7380 O O . HOH H 4 . ? 23.089 92.787 36.604 1.00 43.97 ? 1174 HOH A O 1 HETATM 7381 O O . HOH H 4 . ? 86.567 118.983 19.208 1.00 27.13 ? 1175 HOH A O 1 HETATM 7382 O O . HOH H 4 . ? 71.049 93.585 49.203 1.00 33.31 ? 1176 HOH A O 1 HETATM 7383 O O . HOH H 4 . ? 51.171 126.836 23.419 1.00 33.28 ? 1177 HOH A O 1 HETATM 7384 O O . HOH H 4 . ? 41.033 113.977 54.361 1.00 48.14 ? 1178 HOH A O 1 HETATM 7385 O O . HOH H 4 . ? 64.618 91.148 48.862 1.00 35.49 ? 1179 HOH A O 1 HETATM 7386 O O . HOH H 4 . ? 65.308 81.000 32.358 1.00 35.61 ? 1180 HOH A O 1 HETATM 7387 O O . HOH H 4 . ? 37.999 98.440 47.153 1.00 25.78 ? 1181 HOH A O 1 HETATM 7388 O O . HOH H 4 . ? 68.043 104.886 -3.678 1.00 40.24 ? 1182 HOH A O 1 HETATM 7389 O O . HOH H 4 . ? 79.032 101.943 11.350 1.00 34.91 ? 1183 HOH A O 1 HETATM 7390 O O . HOH H 4 . ? 39.414 102.635 -14.588 1.00 39.28 ? 1184 HOH A O 1 HETATM 7391 O O . HOH H 4 . ? 50.653 59.392 -2.291 1.00 37.97 ? 1185 HOH A O 1 HETATM 7392 O O . HOH H 4 . ? 61.426 72.075 7.094 1.00 31.21 ? 1186 HOH A O 1 HETATM 7393 O O . HOH H 4 . ? 59.304 93.131 48.189 1.00 29.00 ? 1187 HOH A O 1 HETATM 7394 O O . HOH H 4 . ? 55.688 115.471 37.766 1.00 29.69 ? 1188 HOH A O 1 HETATM 7395 O O . HOH H 4 . ? 20.847 95.218 30.141 1.00 43.24 ? 1189 HOH A O 1 HETATM 7396 O O . HOH H 4 . ? 56.460 67.669 4.744 1.00 29.33 ? 1190 HOH A O 1 HETATM 7397 O O . HOH H 4 . ? 62.286 122.700 41.893 1.00 33.89 ? 1191 HOH A O 1 HETATM 7398 O O . HOH H 4 . ? 39.562 95.490 46.749 1.00 37.16 ? 1192 HOH A O 1 HETATM 7399 O O . HOH H 4 . ? 23.954 101.492 20.058 1.00 24.00 ? 1193 HOH A O 1 HETATM 7400 O O . HOH H 4 . ? 54.101 117.253 36.467 1.00 32.70 ? 1194 HOH A O 1 HETATM 7401 O O . HOH H 4 . ? 48.646 118.018 38.815 1.00 46.80 ? 1195 HOH A O 1 HETATM 7402 O O . HOH H 4 . ? 22.009 82.977 13.582 1.00 30.49 ? 1196 HOH A O 1 HETATM 7403 O O . HOH H 4 . ? 77.015 109.293 12.792 1.00 47.92 ? 1197 HOH A O 1 HETATM 7404 O O . HOH H 4 . ? 45.510 112.249 20.435 1.00 38.56 ? 1198 HOH A O 1 HETATM 7405 O O . HOH H 4 . ? 54.976 114.389 -7.751 1.00 45.52 ? 1199 HOH A O 1 HETATM 7406 O O . HOH H 4 . ? 65.542 86.061 -1.209 1.00 31.27 ? 1200 HOH A O 1 HETATM 7407 O O . HOH H 4 . ? 56.540 100.518 54.391 1.00 44.70 ? 1201 HOH A O 1 HETATM 7408 O O . HOH H 4 . ? 37.519 98.319 -14.953 1.00 51.91 ? 1202 HOH A O 1 HETATM 7409 O O . HOH H 4 . ? 50.223 70.528 5.525 1.00 47.33 ? 1203 HOH A O 1 HETATM 7410 O O . HOH H 4 . ? 37.786 72.396 -5.830 1.00 53.06 ? 1204 HOH A O 1 HETATM 7411 O O . HOH H 4 . ? 52.488 69.091 5.359 1.00 29.40 ? 1205 HOH A O 1 HETATM 7412 O O . HOH H 4 . ? 67.011 87.939 24.751 1.00 49.68 ? 1206 HOH A O 1 HETATM 7413 O O . HOH H 4 . ? 46.578 78.434 20.502 1.00 36.62 ? 1207 HOH A O 1 HETATM 7414 O O . HOH H 4 . ? 61.027 82.310 -4.477 1.00 46.76 ? 1208 HOH A O 1 HETATM 7415 O O . HOH H 4 . ? 72.481 97.233 -2.527 1.00 33.04 ? 1209 HOH A O 1 HETATM 7416 O O . HOH H 4 . ? 63.079 71.866 2.936 1.00 32.89 ? 1210 HOH A O 1 HETATM 7417 O O . HOH H 4 . ? 71.592 105.963 8.217 1.00 29.50 ? 1211 HOH A O 1 HETATM 7418 O O . HOH H 4 . ? 41.568 103.392 4.095 1.00 25.09 ? 1212 HOH A O 1 HETATM 7419 O O . HOH H 4 . ? 22.234 100.385 22.775 1.00 29.49 ? 1213 HOH A O 1 HETATM 7420 O O . HOH H 4 . ? 60.586 119.911 12.384 1.00 56.48 ? 1214 HOH A O 1 HETATM 7421 O O . HOH H 4 . ? 90.824 102.340 24.735 1.00 55.33 ? 1215 HOH A O 1 HETATM 7422 O O . HOH H 4 . ? 62.795 99.046 -12.550 1.00 40.00 ? 1216 HOH A O 1 HETATM 7423 O O . HOH H 4 . ? 42.366 105.297 -9.874 1.00 40.21 ? 1217 HOH A O 1 HETATM 7424 O O . HOH H 4 . ? 85.438 108.889 35.189 1.00 41.32 ? 1218 HOH A O 1 HETATM 7425 O O . HOH H 4 . ? 87.594 103.365 17.021 1.00 38.46 ? 1219 HOH A O 1 HETATM 7426 O O . HOH H 4 . ? 36.489 114.643 49.826 1.00 34.61 ? 1220 HOH A O 1 HETATM 7427 O O . HOH H 4 . ? 53.016 118.765 19.749 1.00 26.39 ? 1221 HOH A O 1 HETATM 7428 O O . HOH H 4 . ? 65.603 84.469 39.536 1.00 40.23 ? 1222 HOH A O 1 HETATM 7429 O O . HOH H 4 . ? 52.177 85.031 46.102 1.00 41.62 ? 1223 HOH A O 1 HETATM 7430 O O . HOH H 4 . ? 51.183 117.573 21.238 1.00 26.20 ? 1224 HOH A O 1 HETATM 7431 O O . HOH H 4 . ? 52.279 111.388 1.986 1.00 42.33 ? 1225 HOH A O 1 HETATM 7432 O O . HOH H 4 . ? 40.664 108.465 -13.525 1.00 37.41 ? 1226 HOH A O 1 HETATM 7433 O O . HOH H 4 . ? 52.677 126.896 28.827 1.00 32.47 ? 1227 HOH A O 1 HETATM 7434 O O . HOH H 4 . ? 36.000 110.357 50.872 1.00 42.78 ? 1228 HOH A O 1 HETATM 7435 O O . HOH H 4 . ? 70.406 101.288 -5.973 1.00 39.35 ? 1229 HOH A O 1 HETATM 7436 O O . HOH H 4 . ? 73.206 116.345 35.470 1.00 37.65 ? 1230 HOH A O 1 HETATM 7437 O O . HOH H 4 . ? 70.186 116.327 41.255 1.00 27.34 ? 1231 HOH A O 1 HETATM 7438 O O . HOH H 4 . ? 43.830 103.711 -10.270 1.00 30.25 ? 1232 HOH A O 1 HETATM 7439 O O . HOH H 4 . ? 55.896 83.055 30.452 1.00 42.28 ? 1233 HOH A O 1 HETATM 7440 O O . HOH H 4 . ? 85.763 130.187 36.060 1.00 29.29 ? 1234 HOH A O 1 HETATM 7441 O O . HOH H 4 . ? 27.932 108.470 38.407 1.00 42.29 ? 1235 HOH A O 1 HETATM 7442 O O . HOH H 4 . ? 25.954 105.743 40.161 1.00 51.36 ? 1236 HOH A O 1 HETATM 7443 O O . HOH H 4 . ? 72.593 108.582 12.904 1.00 26.37 ? 1237 HOH A O 1 HETATM 7444 O O . HOH H 4 . ? 18.310 91.068 26.848 1.00 52.41 ? 1238 HOH A O 1 HETATM 7445 O O . HOH H 4 . ? 52.237 81.136 16.445 1.00 38.50 ? 1239 HOH A O 1 HETATM 7446 O O . HOH H 4 . ? 50.635 112.711 0.251 1.00 38.66 ? 1240 HOH A O 1 HETATM 7447 O O . HOH H 4 . ? 82.004 83.779 31.625 1.00 37.76 ? 1241 HOH A O 1 HETATM 7448 O O . HOH H 4 . ? 39.802 98.051 -15.369 1.00 36.85 ? 1242 HOH A O 1 HETATM 7449 O O . HOH H 4 . ? 69.260 106.103 9.392 1.00 22.53 ? 1243 HOH A O 1 HETATM 7450 O O . HOH H 4 . ? 49.485 86.550 33.067 1.00 42.12 ? 1244 HOH A O 1 HETATM 7451 O O . HOH H 4 . ? 80.237 119.021 13.430 1.00 42.06 ? 1245 HOH A O 1 HETATM 7452 O O . HOH H 4 . ? 78.127 102.991 31.675 1.00 33.62 ? 1246 HOH A O 1 HETATM 7453 O O . HOH H 4 . ? 66.348 124.243 40.583 1.00 27.41 ? 1247 HOH A O 1 HETATM 7454 O O . HOH H 4 . ? 89.435 108.452 24.255 1.00 40.11 ? 1248 HOH A O 1 HETATM 7455 O O . HOH H 4 . ? 63.393 82.528 22.962 1.00 43.99 ? 1249 HOH A O 1 HETATM 7456 O O . HOH H 4 . ? 55.140 120.372 31.596 1.00 29.55 ? 1250 HOH A O 1 HETATM 7457 O O . HOH H 4 . ? 30.789 116.126 24.571 1.00 23.73 ? 1251 HOH A O 1 HETATM 7458 O O . HOH H 4 . ? 60.876 87.589 -7.841 1.00 39.87 ? 1252 HOH A O 1 HETATM 7459 O O . HOH H 4 . ? 37.879 74.939 7.995 1.00 30.09 ? 1253 HOH A O 1 HETATM 7460 O O . HOH H 4 . ? 52.325 66.948 6.626 1.00 30.72 ? 1254 HOH A O 1 HETATM 7461 O O . HOH H 4 . ? 85.787 113.493 34.654 1.00 44.70 ? 1255 HOH A O 1 HETATM 7462 O O . HOH H 4 . ? 59.208 80.852 31.016 1.00 42.46 ? 1256 HOH A O 1 HETATM 7463 O O . HOH H 4 . ? 74.683 86.914 30.334 1.00 32.72 ? 1257 HOH A O 1 HETATM 7464 O O . HOH H 4 . ? 83.536 95.274 30.473 1.00 40.92 ? 1258 HOH A O 1 HETATM 7465 O O . HOH H 4 . ? 57.235 64.379 4.163 1.00 44.71 ? 1259 HOH A O 1 HETATM 7466 O O . HOH H 4 . ? 57.666 105.430 54.364 1.00 36.56 ? 1260 HOH A O 1 HETATM 7467 O O . HOH H 4 . ? 72.699 113.869 15.752 1.00 49.63 ? 1261 HOH A O 1 HETATM 7468 O O . HOH H 4 . ? 51.586 121.073 37.588 1.00 35.51 ? 1262 HOH A O 1 HETATM 7469 O O . HOH H 4 . ? 63.702 107.183 -1.667 1.00 39.53 ? 1263 HOH A O 1 HETATM 7470 O O . HOH H 4 . ? 19.623 88.950 19.034 1.00 39.98 ? 1264 HOH A O 1 HETATM 7471 O O . HOH H 4 . ? 84.051 131.796 21.545 1.00 32.63 ? 1265 HOH A O 1 HETATM 7472 O O . HOH H 4 . ? 37.322 105.389 5.002 1.00 37.19 ? 1266 HOH A O 1 HETATM 7473 O O . HOH H 4 . ? 29.692 115.160 26.633 1.00 36.94 ? 1267 HOH A O 1 HETATM 7474 O O . HOH H 4 . ? 55.300 103.988 53.898 1.00 32.96 ? 1268 HOH A O 1 HETATM 7475 O O . HOH H 4 . ? 61.925 101.217 51.976 1.00 42.87 ? 1269 HOH A O 1 HETATM 7476 O O . HOH H 4 . ? 71.347 116.188 15.227 1.00 44.28 ? 1270 HOH A O 1 HETATM 7477 O O . HOH H 4 . ? 35.556 78.505 14.574 1.00 31.67 ? 1271 HOH A O 1 HETATM 7478 O O . HOH H 4 . ? 80.854 104.894 12.800 1.00 32.89 ? 1272 HOH A O 1 HETATM 7479 O O . HOH H 4 . ? 78.090 112.889 13.899 1.00 32.26 ? 1273 HOH A O 1 HETATM 7480 O O . HOH H 4 . ? 75.209 116.166 32.169 1.00 59.81 ? 1274 HOH A O 1 HETATM 7481 O O . HOH H 4 . ? 68.729 108.764 2.349 1.00 51.63 ? 1275 HOH A O 1 HETATM 7482 O O . HOH H 4 . ? 87.258 111.591 35.355 1.00 38.71 ? 1276 HOH A O 1 HETATM 7483 O O . HOH H 4 . ? 56.946 63.930 7.615 1.00 45.29 ? 1277 HOH A O 1 HETATM 7484 O O . HOH H 4 . ? 23.177 87.328 23.543 1.00 37.12 ? 1278 HOH A O 1 HETATM 7485 O O . HOH H 4 . ? 70.338 90.595 2.485 1.00 37.47 ? 1279 HOH A O 1 HETATM 7486 O O . HOH H 4 . ? 37.884 68.103 3.169 1.00 48.23 ? 1280 HOH A O 1 HETATM 7487 O O . HOH H 4 . ? 51.360 117.507 40.377 1.00 35.97 ? 1281 HOH A O 1 HETATM 7488 O O . HOH H 4 . ? 46.806 86.568 31.101 1.00 25.99 ? 1282 HOH A O 1 HETATM 7489 O O . HOH H 4 . ? 62.067 87.976 -4.782 1.00 30.64 ? 1283 HOH A O 1 HETATM 7490 O O . HOH H 4 . ? 32.251 107.326 46.759 1.00 44.33 ? 1284 HOH A O 1 HETATM 7491 O O . HOH H 4 . ? 56.316 90.505 27.251 1.00 34.44 ? 1285 HOH A O 1 HETATM 7492 O O . HOH H 4 . ? 59.880 82.531 10.711 1.00 18.72 ? 1286 HOH A O 1 HETATM 7493 O O . HOH H 4 . ? 43.767 107.005 13.317 1.00 20.74 ? 1287 HOH A O 1 HETATM 7494 O O . HOH H 4 . ? 39.269 96.845 48.713 1.00 22.48 ? 1288 HOH A O 1 HETATM 7495 O O . HOH H 4 . ? 33.849 82.179 1.913 1.00 21.04 ? 1289 HOH A O 1 HETATM 7496 O O . HOH H 4 . ? 72.689 108.174 38.739 1.00 22.66 ? 1290 HOH A O 1 HETATM 7497 O O . HOH H 4 . ? 48.573 109.436 25.360 1.00 22.90 ? 1291 HOH A O 1 HETATM 7498 O O . HOH H 4 . ? 28.076 79.590 17.752 1.00 29.95 ? 1292 HOH A O 1 HETATM 7499 O O . HOH H 4 . ? 32.595 83.758 -2.065 1.00 24.60 ? 1293 HOH A O 1 HETATM 7500 O O . HOH H 4 . ? 41.444 105.719 53.771 1.00 33.41 ? 1294 HOH A O 1 HETATM 7501 O O . HOH H 4 . ? 39.906 87.251 33.668 1.00 45.00 ? 1295 HOH A O 1 HETATM 7502 O O . HOH H 4 . ? 38.385 87.333 29.017 1.00 23.58 ? 1296 HOH A O 1 HETATM 7503 O O . HOH H 4 . ? 51.311 118.617 16.944 1.00 29.47 ? 1297 HOH A O 1 HETATM 7504 O O . HOH H 4 . ? 38.805 85.715 31.163 1.00 32.79 ? 1298 HOH A O 1 HETATM 7505 O O . HOH H 4 . ? 64.253 103.861 -14.602 1.00 26.36 ? 1299 HOH A O 1 HETATM 7506 O O . HOH H 4 . ? 78.903 99.973 30.659 1.00 31.37 ? 1300 HOH A O 1 HETATM 7507 O O . HOH H 4 . ? 73.937 91.427 25.026 1.00 32.92 ? 1301 HOH A O 1 HETATM 7508 O O . HOH H 4 . ? 45.693 117.193 34.685 1.00 29.80 ? 1302 HOH A O 1 HETATM 7509 O O . HOH H 4 . ? 67.468 118.096 42.026 1.00 28.70 ? 1303 HOH A O 1 HETATM 7510 O O . HOH H 4 . ? 57.432 109.684 52.412 1.00 33.09 ? 1304 HOH A O 1 HETATM 7511 O O . HOH H 4 . ? 50.485 112.067 24.340 1.00 32.92 ? 1305 HOH A O 1 HETATM 7512 O O . HOH H 4 . ? 74.638 102.391 2.285 1.00 33.67 ? 1306 HOH A O 1 HETATM 7513 O O . HOH H 4 . ? 37.581 91.561 13.297 1.00 30.27 ? 1307 HOH A O 1 HETATM 7514 O O . HOH H 4 . ? 74.944 134.561 28.299 1.00 35.50 ? 1308 HOH A O 1 HETATM 7515 O O . HOH H 4 . ? 43.734 122.554 30.738 1.00 36.04 ? 1309 HOH A O 1 HETATM 7516 O O . HOH H 4 . ? 40.125 114.587 43.673 1.00 29.72 ? 1310 HOH A O 1 HETATM 7517 O O . HOH H 4 . ? 29.194 77.382 18.495 1.00 37.52 ? 1311 HOH A O 1 HETATM 7518 O O . HOH H 4 . ? 25.391 97.874 12.147 1.00 39.08 ? 1312 HOH A O 1 HETATM 7519 O O . HOH H 4 . ? 47.909 87.423 37.960 1.00 33.11 ? 1313 HOH A O 1 HETATM 7520 O O . HOH H 4 . ? 74.521 87.840 6.378 1.00 47.25 ? 1314 HOH A O 1 HETATM 7521 O O . HOH H 4 . ? 94.677 115.336 33.949 1.00 43.14 ? 1315 HOH A O 1 HETATM 7522 O O . HOH H 4 . ? 73.333 125.998 11.723 1.00 45.72 ? 1316 HOH A O 1 HETATM 7523 O O . HOH H 4 . ? 89.905 127.331 30.082 1.00 36.30 ? 1317 HOH A O 1 HETATM 7524 O O . HOH H 4 . ? 23.033 107.262 19.053 1.00 38.94 ? 1318 HOH A O 1 HETATM 7525 O O . HOH H 4 . ? 30.322 90.757 7.670 1.00 31.45 ? 1319 HOH A O 1 HETATM 7526 O O . HOH H 4 . ? 37.592 103.831 55.959 1.00 34.83 ? 1320 HOH A O 1 HETATM 7527 O O . HOH H 4 . ? 64.148 119.767 10.904 1.00 44.75 ? 1321 HOH A O 1 HETATM 7528 O O . HOH H 4 . ? 67.827 104.543 55.284 1.00 38.69 ? 1322 HOH A O 1 HETATM 7529 O O . HOH H 4 . ? 84.646 101.750 19.706 1.00 30.78 ? 1323 HOH A O 1 HETATM 7530 O O . HOH H 4 . ? 51.154 102.486 -14.606 1.00 36.06 ? 1324 HOH A O 1 HETATM 7531 O O . HOH H 4 . ? 32.393 77.106 2.580 1.00 48.01 ? 1325 HOH A O 1 HETATM 7532 O O . HOH H 4 . ? 87.988 110.662 19.597 1.00 43.08 ? 1326 HOH A O 1 HETATM 7533 O O . HOH H 4 . ? 48.804 119.685 32.705 1.00 33.36 ? 1327 HOH A O 1 HETATM 7534 O O . HOH H 4 . ? 81.299 91.597 13.059 1.00 38.02 ? 1328 HOH A O 1 HETATM 7535 O O . HOH H 4 . ? 94.758 124.311 18.634 1.00 43.65 ? 1329 HOH A O 1 HETATM 7536 O O . HOH H 4 . ? 97.051 130.193 27.356 1.00 50.80 ? 1330 HOH A O 1 HETATM 7537 O O . HOH H 4 . ? 79.965 97.300 34.655 1.00 39.67 ? 1331 HOH A O 1 HETATM 7538 O O . HOH H 4 . ? 36.547 76.899 10.798 1.00 39.93 ? 1332 HOH A O 1 HETATM 7539 O O . HOH H 4 . ? 43.440 77.131 11.515 1.00 31.10 ? 1333 HOH A O 1 HETATM 7540 O O . HOH H 4 . ? 81.319 118.337 37.417 1.00 45.14 ? 1334 HOH A O 1 HETATM 7541 O O . HOH H 4 . ? 66.632 115.687 44.844 1.00 34.37 ? 1335 HOH A O 1 HETATM 7542 O O . HOH H 4 . ? 35.810 121.966 29.424 1.00 41.65 ? 1336 HOH A O 1 HETATM 7543 O O . HOH H 4 . ? 48.584 106.113 -15.125 1.00 33.38 ? 1337 HOH A O 1 HETATM 7544 O O . HOH H 4 . ? 23.202 86.387 12.693 1.00 29.64 ? 1338 HOH A O 1 HETATM 7545 O O . HOH H 4 . ? 24.723 85.119 18.389 1.00 33.67 ? 1339 HOH A O 1 HETATM 7546 O O . HOH H 4 . ? 66.526 113.698 46.590 1.00 42.84 ? 1340 HOH A O 1 HETATM 7547 O O . HOH H 4 . ? 63.761 105.896 -16.047 1.00 33.17 ? 1341 HOH A O 1 HETATM 7548 O O . HOH H 4 . ? 27.017 96.108 -3.330 1.00 41.35 ? 1342 HOH A O 1 HETATM 7549 O O . HOH H 4 . ? 86.901 119.738 12.743 1.00 33.68 ? 1343 HOH A O 1 HETATM 7550 O O . HOH H 4 . ? 33.645 101.038 6.360 1.00 29.81 ? 1344 HOH A O 1 HETATM 7551 O O . HOH H 4 . ? 47.499 76.260 9.312 1.00 32.32 ? 1345 HOH A O 1 HETATM 7552 O O . HOH H 4 . ? 78.710 109.420 35.309 1.00 39.66 ? 1346 HOH A O 1 HETATM 7553 O O . HOH H 4 . ? 22.060 111.153 35.234 1.00 34.28 ? 1347 HOH A O 1 HETATM 7554 O O . HOH H 4 . ? 25.005 80.895 8.137 1.00 31.84 ? 1348 HOH A O 1 HETATM 7555 O O . HOH H 4 . ? 68.146 94.238 -14.185 1.00 37.62 ? 1349 HOH A O 1 HETATM 7556 O O . HOH H 4 . ? 69.065 93.875 -7.186 1.00 33.35 ? 1350 HOH A O 1 HETATM 7557 O O . HOH H 4 . ? 32.159 89.444 -8.835 1.00 34.54 ? 1351 HOH A O 1 HETATM 7558 O O . HOH H 4 . ? 63.977 116.694 8.791 1.00 42.38 ? 1352 HOH A O 1 HETATM 7559 O O . HOH H 4 . ? 51.883 114.573 11.768 1.00 40.22 ? 1353 HOH A O 1 HETATM 7560 O O . HOH H 4 . ? 48.611 124.171 20.483 1.00 35.16 ? 1354 HOH A O 1 HETATM 7561 O O . HOH H 4 . ? 30.560 81.831 -1.263 1.00 40.34 ? 1355 HOH A O 1 HETATM 7562 O O . HOH H 4 . ? 40.728 86.401 35.911 1.00 40.81 ? 1356 HOH A O 1 HETATM 7563 O O . HOH H 4 . ? 30.801 86.489 -7.714 1.00 31.40 ? 1357 HOH A O 1 HETATM 7564 O O . HOH H 4 . ? 32.052 101.134 8.430 1.00 33.02 ? 1358 HOH A O 1 HETATM 7565 O O . HOH H 4 . ? 32.955 114.685 20.786 1.00 41.17 ? 1359 HOH A O 1 HETATM 7566 O O . HOH H 4 . ? 64.789 116.692 46.590 1.00 47.57 ? 1360 HOH A O 1 HETATM 7567 O O . HOH H 4 . ? 45.871 82.079 -16.647 1.00 48.50 ? 1361 HOH A O 1 HETATM 7568 O O . HOH H 4 . ? 67.786 113.882 14.134 1.00 38.62 ? 1362 HOH A O 1 HETATM 7569 O O . HOH H 4 . ? 62.318 67.429 8.249 1.00 50.31 ? 1363 HOH A O 1 HETATM 7570 O O . HOH H 4 . ? 37.158 111.272 54.214 1.00 41.91 ? 1364 HOH A O 1 HETATM 7571 O O . HOH H 4 . ? 49.226 92.351 48.412 1.00 41.59 ? 1365 HOH A O 1 HETATM 7572 O O . HOH H 4 . ? 18.490 87.545 15.561 1.00 42.42 ? 1366 HOH A O 1 HETATM 7573 O O . HOH H 4 . ? 38.514 109.780 3.118 1.00 43.42 ? 1367 HOH A O 1 HETATM 7574 O O . HOH H 4 . ? 73.914 120.390 34.287 1.00 31.57 ? 1368 HOH A O 1 HETATM 7575 O O . HOH H 4 . ? 69.028 103.740 49.838 1.00 31.63 ? 1369 HOH A O 1 HETATM 7576 O O . HOH H 4 . ? 85.555 102.810 32.631 1.00 45.63 ? 1370 HOH A O 1 HETATM 7577 O O . HOH H 4 . ? 32.412 88.858 36.991 1.00 38.80 ? 1371 HOH A O 1 HETATM 7578 O O . HOH H 4 . ? 57.313 129.960 13.463 1.00 35.80 ? 1372 HOH A O 1 HETATM 7579 O O . HOH H 4 . ? 66.616 130.918 29.059 1.00 35.30 ? 1373 HOH A O 1 HETATM 7580 O O . HOH H 4 . ? 78.988 99.931 33.786 1.00 37.93 ? 1374 HOH A O 1 HETATM 7581 O O . HOH H 4 . ? 33.379 76.610 12.095 1.00 45.53 ? 1375 HOH A O 1 HETATM 7582 O O . HOH H 4 . ? 43.180 117.153 36.604 1.00 48.62 ? 1376 HOH A O 1 HETATM 7583 O O . HOH H 4 . ? 81.299 110.073 12.951 1.00 30.57 ? 1377 HOH A O 1 HETATM 7584 O O . HOH H 4 . ? 72.992 89.972 40.478 1.00 30.88 ? 1378 HOH A O 1 HETATM 7585 O O . HOH H 4 . ? 50.957 81.123 30.298 1.00 42.35 ? 1379 HOH A O 1 HETATM 7586 O O . HOH H 4 . ? 38.188 72.619 6.891 1.00 33.14 ? 1380 HOH A O 1 HETATM 7587 O O . HOH H 4 . ? 61.233 109.117 4.812 1.00 41.61 ? 1381 HOH A O 1 HETATM 7588 O O . HOH H 4 . ? 65.174 81.608 3.880 1.00 37.91 ? 1382 HOH A O 1 HETATM 7589 O O . HOH H 4 . ? 69.885 87.786 6.614 1.00 36.01 ? 1383 HOH A O 1 HETATM 7590 O O . HOH H 4 . ? 33.521 85.058 35.500 1.00 41.23 ? 1384 HOH A O 1 HETATM 7591 O O . HOH H 4 . ? 49.411 80.124 17.072 1.00 40.86 ? 1385 HOH A O 1 HETATM 7592 O O . HOH H 4 . ? 36.189 79.071 -6.341 1.00 40.66 ? 1386 HOH A O 1 HETATM 7593 O O . HOH H 4 . ? 36.528 106.607 10.773 1.00 35.35 ? 1387 HOH A O 1 HETATM 7594 O O . HOH H 4 . ? 20.548 109.089 34.947 1.00 44.38 ? 1388 HOH A O 1 HETATM 7595 O O . HOH H 4 . ? 39.220 81.763 -1.402 1.00 27.75 ? 1389 HOH A O 1 HETATM 7596 O O . HOH H 4 . ? 69.357 107.208 11.708 1.00 26.97 ? 1390 HOH A O 1 HETATM 7597 O O . HOH H 4 . ? 39.588 105.202 56.487 1.00 43.04 ? 1391 HOH A O 1 HETATM 7598 O O . HOH H 4 . ? 95.535 122.241 25.878 1.00 28.56 ? 1392 HOH A O 1 HETATM 7599 O O . HOH H 4 . ? 29.817 75.328 3.232 1.00 51.63 ? 1393 HOH A O 1 HETATM 7600 O O . HOH H 4 . ? 46.052 108.095 1.438 1.00 35.65 ? 1394 HOH A O 1 HETATM 7601 O O . HOH H 4 . ? 21.967 90.982 33.232 1.00 31.41 ? 1395 HOH A O 1 HETATM 7602 O O . HOH H 4 . ? 64.140 87.433 23.345 1.00 31.59 ? 1396 HOH A O 1 HETATM 7603 O O . HOH H 4 . ? 54.483 123.839 31.426 1.00 37.39 ? 1397 HOH A O 1 HETATM 7604 O O . HOH H 4 . ? 48.653 88.908 49.446 1.00 41.50 ? 1398 HOH A O 1 HETATM 7605 O O . HOH H 4 . ? 70.279 130.037 34.997 1.00 35.81 ? 1399 HOH A O 1 HETATM 7606 O O . HOH H 4 . ? 56.184 110.798 19.969 1.00 27.71 ? 1400 HOH A O 1 HETATM 7607 O O . HOH H 4 . ? 48.912 104.424 55.076 1.00 38.35 ? 1401 HOH A O 1 HETATM 7608 O O . HOH H 4 . ? 63.314 85.891 -3.187 1.00 38.96 ? 1402 HOH A O 1 HETATM 7609 O O . HOH H 4 . ? 22.489 110.411 29.101 1.00 43.94 ? 1403 HOH A O 1 HETATM 7610 O O . HOH H 4 . ? 45.192 115.550 -14.216 1.00 44.99 ? 1404 HOH A O 1 HETATM 7611 O O . HOH H 4 . ? 74.307 133.895 16.020 1.00 48.20 ? 1405 HOH A O 1 HETATM 7612 O O . HOH H 4 . ? 29.793 97.938 7.696 1.00 40.59 ? 1406 HOH A O 1 HETATM 7613 O O . HOH H 4 . ? 87.938 103.961 33.871 1.00 50.74 ? 1407 HOH A O 1 HETATM 7614 O O . HOH H 4 . ? 98.748 121.174 23.402 1.00 43.86 ? 1408 HOH A O 1 HETATM 7615 O O . HOH H 4 . ? 34.471 97.801 46.601 1.00 28.77 ? 1409 HOH A O 1 HETATM 7616 O O . HOH H 4 . ? 49.619 86.618 51.327 1.00 46.15 ? 1410 HOH A O 1 HETATM 7617 O O . HOH H 4 . ? 20.242 92.321 39.902 1.00 44.39 ? 1411 HOH A O 1 HETATM 7618 O O . HOH H 4 . ? 65.836 79.840 0.442 1.00 43.67 ? 1412 HOH A O 1 HETATM 7619 O O . HOH H 4 . ? 22.607 93.434 41.958 1.00 47.33 ? 1413 HOH A O 1 HETATM 7620 O O . HOH H 4 . ? 19.186 95.357 34.413 1.00 46.81 ? 1414 HOH A O 1 HETATM 7621 O O . HOH H 4 . ? 28.029 90.522 40.248 1.00 47.17 ? 1415 HOH A O 1 HETATM 7622 O O . HOH H 4 . ? 48.084 94.980 49.222 1.00 36.73 ? 1416 HOH A O 1 HETATM 7623 O O . HOH H 4 . ? 41.572 75.101 10.642 1.00 44.16 ? 1417 HOH A O 1 HETATM 7624 O O . HOH H 4 . ? 92.242 112.239 22.508 1.00 40.75 ? 1418 HOH A O 1 HETATM 7625 O O . HOH H 4 . ? 20.469 110.659 31.026 1.00 49.83 ? 1419 HOH A O 1 HETATM 7626 O O . HOH H 4 . ? 35.775 106.306 18.442 1.00 30.42 ? 1420 HOH A O 1 HETATM 7627 O O . HOH H 4 . ? 68.212 109.498 14.269 1.00 33.88 ? 1421 HOH A O 1 HETATM 7628 O O . HOH H 4 . ? 35.297 97.737 -6.773 1.00 35.85 ? 1422 HOH A O 1 HETATM 7629 O O . HOH H 4 . ? 67.901 84.498 41.433 1.00 36.37 ? 1423 HOH A O 1 HETATM 7630 O O . HOH H 4 . ? 73.838 87.906 25.151 1.00 34.41 ? 1424 HOH A O 1 HETATM 7631 O O . HOH H 4 . ? 55.145 68.504 8.855 1.00 44.14 ? 1425 HOH A O 1 HETATM 7632 O O . HOH H 4 . ? 73.875 131.080 15.230 1.00 37.28 ? 1426 HOH A O 1 HETATM 7633 O O . HOH H 4 . ? 33.731 98.151 -9.995 1.00 44.32 ? 1427 HOH A O 1 HETATM 7634 O O . HOH H 4 . ? 61.423 91.618 49.043 1.00 40.20 ? 1428 HOH A O 1 HETATM 7635 O O . HOH H 4 . ? 38.878 94.326 -19.227 1.00 40.00 ? 1429 HOH A O 1 HETATM 7636 O O . HOH H 4 . ? 42.755 119.704 23.617 1.00 40.96 ? 1430 HOH A O 1 HETATM 7637 O O . HOH H 4 . ? 48.009 85.815 44.202 1.00 35.80 ? 1431 HOH A O 1 HETATM 7638 O O . HOH H 4 . ? 60.608 133.072 21.776 1.00 44.76 ? 1432 HOH A O 1 HETATM 7639 O O . HOH H 4 . ? 72.919 100.307 -2.818 1.00 38.76 ? 1433 HOH A O 1 HETATM 7640 O O . HOH H 4 . ? 70.794 110.413 13.346 1.00 32.94 ? 1434 HOH A O 1 HETATM 7641 O O . HOH H 4 . ? 78.187 134.866 27.208 1.00 41.90 ? 1435 HOH A O 1 HETATM 7642 O O . HOH H 4 . ? 93.212 126.711 30.185 1.00 39.52 ? 1436 HOH A O 1 HETATM 7643 O O . HOH H 4 . ? 23.060 99.671 41.128 1.00 36.87 ? 1437 HOH A O 1 HETATM 7644 O O . HOH H 4 . ? 39.342 78.577 -8.193 1.00 41.86 ? 1438 HOH A O 1 HETATM 7645 O O . HOH H 4 . ? 35.134 117.763 35.220 1.00 47.06 ? 1439 HOH A O 1 HETATM 7646 O O . HOH H 4 . ? 20.650 107.445 37.135 1.00 38.76 ? 1440 HOH A O 1 HETATM 7647 O O . HOH H 4 . ? 56.534 97.799 -15.686 1.00 44.58 ? 1441 HOH A O 1 HETATM 7648 O O . HOH H 4 . ? 23.957 88.482 11.131 1.00 40.42 ? 1442 HOH A O 1 HETATM 7649 O O . HOH H 4 . ? 41.636 119.392 33.616 1.00 37.26 ? 1443 HOH A O 1 HETATM 7650 O O . HOH H 4 . ? 46.582 125.536 22.151 1.00 37.74 ? 1444 HOH A O 1 HETATM 7651 O O . HOH H 4 . ? 63.232 123.714 13.067 1.00 39.59 ? 1445 HOH A O 1 HETATM 7652 O O . HOH H 4 . ? 76.871 103.131 10.364 1.00 40.83 ? 1446 HOH A O 1 HETATM 7653 O O . HOH H 4 . ? 35.047 91.648 -16.421 1.00 49.07 ? 1447 HOH A O 1 HETATM 7654 O O . HOH H 4 . ? 27.252 98.242 8.224 1.00 38.99 ? 1448 HOH A O 1 HETATM 7655 O O . HOH H 4 . ? 19.662 100.535 23.535 1.00 35.88 ? 1449 HOH A O 1 HETATM 7656 O O . HOH H 4 . ? 38.290 69.913 9.247 1.00 40.72 ? 1450 HOH A O 1 HETATM 7657 O O . HOH H 4 . ? 41.306 111.938 -10.315 1.00 50.21 ? 1451 HOH A O 1 HETATM 7658 O O . HOH H 4 . ? 21.788 112.398 27.277 1.00 43.37 ? 1452 HOH A O 1 HETATM 7659 O O . HOH H 4 . ? 58.771 134.117 19.809 1.00 51.98 ? 1453 HOH A O 1 HETATM 7660 O O . HOH H 4 . ? 36.908 85.048 34.778 1.00 54.46 ? 1454 HOH A O 1 HETATM 7661 O O . HOH H 4 . ? 31.453 81.783 2.724 1.00 52.67 ? 1455 HOH A O 1 HETATM 7662 O O . HOH H 4 . ? 42.276 93.637 48.484 1.00 41.44 ? 1456 HOH A O 1 HETATM 7663 O O . HOH H 4 . ? 44.160 98.650 54.806 1.00 36.97 ? 1457 HOH A O 1 HETATM 7664 O O . HOH H 4 . ? 12.111 105.050 16.607 1.00 56.19 ? 1458 HOH A O 1 HETATM 7665 O O . HOH H 4 . ? 68.066 120.273 14.590 1.00 48.04 ? 1459 HOH A O 1 HETATM 7666 O O . HOH H 4 . ? 28.206 79.694 22.217 1.00 48.44 ? 1460 HOH A O 1 HETATM 7667 O O . HOH H 4 . ? 32.009 112.842 19.078 1.00 41.73 ? 1461 HOH A O 1 HETATM 7668 O O . HOH H 4 . ? 33.174 107.201 15.237 1.00 40.85 ? 1462 HOH A O 1 HETATM 7669 O O . HOH H 4 . ? 35.244 103.219 5.018 1.00 50.01 ? 1463 HOH A O 1 HETATM 7670 O O . HOH H 4 . ? 66.363 128.966 36.564 1.00 39.04 ? 1464 HOH A O 1 HETATM 7671 O O . HOH H 4 . ? 47.036 84.345 -9.457 1.00 32.16 ? 1465 HOH A O 1 HETATM 7672 O O . HOH H 4 . ? 61.885 109.992 -2.942 1.00 37.72 ? 1466 HOH A O 1 HETATM 7673 O O . HOH H 4 . ? 76.874 107.685 36.381 1.00 33.52 ? 1467 HOH A O 1 HETATM 7674 O O . HOH H 4 . ? 84.598 133.858 27.317 1.00 39.06 ? 1468 HOH A O 1 HETATM 7675 O O . HOH H 4 . ? 52.352 85.472 -13.070 1.00 40.89 ? 1469 HOH A O 1 HETATM 7676 O O . HOH H 4 . ? 56.763 81.773 19.791 1.00 47.93 ? 1470 HOH A O 1 HETATM 7677 O O . HOH H 4 . ? 48.784 73.450 7.631 1.00 39.26 ? 1471 HOH A O 1 HETATM 7678 O O . HOH H 4 . ? 45.949 111.362 6.249 1.00 38.53 ? 1472 HOH A O 1 HETATM 7679 O O . HOH H 4 . ? 63.546 110.846 52.754 1.00 40.48 ? 1473 HOH A O 1 HETATM 7680 O O . HOH H 4 . ? 52.468 95.816 -15.817 1.00 31.36 ? 1474 HOH A O 1 HETATM 7681 O O . HOH H 4 . ? 51.917 83.357 -11.053 1.00 45.02 ? 1475 HOH A O 1 HETATM 7682 O O . HOH H 4 . ? 74.556 82.485 34.678 1.00 45.48 ? 1476 HOH A O 1 HETATM 7683 O O . HOH H 4 . ? 30.532 109.838 38.188 1.00 41.68 ? 1477 HOH A O 1 HETATM 7684 O O . HOH H 4 . ? 50.342 129.405 17.375 1.00 43.55 ? 1478 HOH A O 1 HETATM 7685 O O . HOH H 4 . ? 21.462 87.203 19.165 1.00 40.48 ? 1479 HOH A O 1 HETATM 7686 O O . HOH H 4 . ? 76.002 129.648 16.937 1.00 37.51 ? 1480 HOH A O 1 HETATM 7687 O O . HOH H 4 . ? 40.354 85.827 28.268 1.00 38.96 ? 1481 HOH A O 1 HETATM 7688 O O . HOH H 4 . ? 55.928 81.030 28.658 1.00 39.58 ? 1482 HOH A O 1 HETATM 7689 O O . HOH H 4 . ? 64.521 129.546 26.206 1.00 42.99 ? 1483 HOH A O 1 HETATM 7690 O O . HOH H 4 . ? 22.486 85.692 16.576 1.00 42.51 ? 1484 HOH A O 1 HETATM 7691 O O . HOH H 4 . ? 75.183 123.951 15.477 1.00 38.18 ? 1485 HOH A O 1 HETATM 7692 O O . HOH H 4 . ? 28.582 77.582 10.503 1.00 41.66 ? 1486 HOH A O 1 HETATM 7693 O O . HOH H 4 . ? 77.142 134.275 15.311 1.00 42.10 ? 1487 HOH A O 1 HETATM 7694 O O . HOH H 4 . ? 48.870 110.734 -13.873 1.00 51.09 ? 1488 HOH A O 1 HETATM 7695 O O . HOH H 4 . ? 39.804 109.181 7.172 1.00 40.73 ? 1489 HOH A O 1 HETATM 7696 O O . HOH H 4 . ? 50.396 78.380 19.394 1.00 45.77 ? 1490 HOH A O 1 HETATM 7697 O O . HOH H 4 . ? 28.752 75.379 12.070 1.00 45.02 ? 1491 HOH A O 1 HETATM 7698 O O . HOH H 4 . ? 59.236 108.208 -12.472 1.00 40.43 ? 1492 HOH A O 1 HETATM 7699 O O . HOH H 4 . ? 19.072 100.696 26.099 1.00 41.18 ? 1493 HOH A O 1 HETATM 7700 O O . HOH H 4 . ? 32.387 99.620 50.387 1.00 37.63 ? 1494 HOH A O 1 HETATM 7701 O O . HOH H 4 . ? 50.667 118.609 50.622 1.00 52.46 ? 1495 HOH A O 1 HETATM 7702 O O . HOH H 4 . ? 63.589 78.934 30.177 1.00 59.05 ? 1496 HOH A O 1 HETATM 7703 O O . HOH H 4 . ? 63.644 107.810 1.053 1.00 36.03 ? 1497 HOH A O 1 HETATM 7704 O O . HOH H 4 . ? 67.142 83.203 8.622 1.00 33.69 ? 1498 HOH A O 1 HETATM 7705 O O . HOH H 4 . ? 54.020 130.238 16.383 1.00 45.33 ? 1499 HOH A O 1 HETATM 7706 O O . HOH H 4 . ? 48.321 82.041 32.022 1.00 40.69 ? 1500 HOH A O 1 HETATM 7707 O O . HOH H 4 . ? 68.388 87.137 4.121 1.00 50.13 ? 1501 HOH A O 1 HETATM 7708 O O . HOH H 4 . ? 38.776 63.256 -3.661 1.00 50.84 ? 1502 HOH A O 1 HETATM 7709 O O . HOH H 4 . ? 42.347 99.708 -21.359 1.00 36.27 ? 1503 HOH A O 1 HETATM 7710 O O . HOH H 4 . ? 23.631 74.370 15.747 1.00 49.03 ? 1504 HOH A O 1 HETATM 7711 O O . HOH H 4 . ? 48.948 76.320 18.405 1.00 48.86 ? 1505 HOH A O 1 HETATM 7712 O O . HOH H 4 . ? 81.041 101.947 33.966 1.00 35.97 ? 1506 HOH A O 1 HETATM 7713 O O . HOH H 4 . ? 31.836 98.203 48.580 1.00 41.93 ? 1507 HOH A O 1 HETATM 7714 O O . HOH H 4 . ? 41.021 116.469 45.018 1.00 39.99 ? 1508 HOH A O 1 HETATM 7715 O O . HOH H 4 . ? 88.419 128.151 17.714 1.00 45.50 ? 1509 HOH A O 1 HETATM 7716 O O . HOH H 4 . ? 61.287 107.355 2.213 1.00 38.94 ? 1510 HOH A O 1 HETATM 7717 O O . HOH H 4 . ? 17.769 103.898 38.123 1.00 45.12 ? 1511 HOH A O 1 HETATM 7718 O O . HOH H 4 . ? 28.898 90.994 43.544 1.00 42.03 ? 1512 HOH A O 1 HETATM 7719 O O . HOH H 4 . ? 49.744 82.925 -9.444 1.00 50.59 ? 1513 HOH A O 1 HETATM 7720 O O . HOH H 4 . ? 83.713 113.402 11.424 1.00 37.64 ? 1514 HOH A O 1 HETATM 7721 O O . HOH H 4 . ? 21.640 112.729 33.110 1.00 37.60 ? 1515 HOH A O 1 HETATM 7722 O O . HOH H 4 . ? 42.096 111.892 8.398 1.00 50.40 ? 1516 HOH A O 1 HETATM 7723 O O . HOH H 4 . ? 27.594 86.110 33.361 1.00 51.40 ? 1517 HOH A O 1 HETATM 7724 O O . HOH H 4 . ? 47.189 86.412 35.419 1.00 48.28 ? 1518 HOH A O 1 HETATM 7725 O O . HOH H 4 . ? 63.917 132.867 30.733 1.00 43.91 ? 1519 HOH A O 1 HETATM 7726 O O . HOH H 4 . ? 31.698 75.137 10.755 1.00 50.93 ? 1520 HOH A O 1 HETATM 7727 O O . HOH H 4 . ? 87.939 96.418 15.760 1.00 38.74 ? 1521 HOH A O 1 HETATM 7728 O O . HOH H 4 . ? 36.989 100.305 -2.905 1.00 49.58 ? 1522 HOH A O 1 HETATM 7729 O O . HOH H 4 . ? 50.685 112.107 -2.447 1.00 38.27 ? 1523 HOH A O 1 HETATM 7730 O O . HOH H 4 . ? 32.124 76.043 0.330 1.00 50.27 ? 1524 HOH A O 1 HETATM 7731 O O . HOH H 4 . ? 74.297 128.648 34.379 1.00 47.76 ? 1525 HOH A O 1 HETATM 7732 O O . HOH H 4 . ? 87.149 95.348 36.538 1.00 51.05 ? 1526 HOH A O 1 HETATM 7733 O O . HOH H 4 . ? 40.465 95.625 -22.757 1.00 34.15 ? 1527 HOH A O 1 HETATM 7734 O O . HOH H 4 . ? 35.986 118.935 42.284 1.00 51.90 ? 1528 HOH A O 1 HETATM 7735 O O . HOH H 4 . ? 35.582 114.706 45.533 1.00 40.57 ? 1529 HOH A O 1 HETATM 7736 O O . HOH H 4 . ? 75.490 129.427 12.937 1.00 51.90 ? 1530 HOH A O 1 HETATM 7737 O O . HOH H 4 . ? 38.415 117.528 46.076 1.00 37.65 ? 1531 HOH A O 1 HETATM 7738 O O . HOH H 4 . ? 62.476 135.517 23.056 1.00 50.26 ? 1532 HOH A O 1 HETATM 7739 O O . HOH H 4 . ? 55.181 122.317 12.577 1.00 46.01 ? 1533 HOH A O 1 HETATM 7740 O O . HOH H 4 . ? 57.091 116.524 51.046 1.00 47.67 ? 1534 HOH A O 1 HETATM 7741 O O . HOH H 4 . ? 74.885 108.781 37.352 1.00 29.11 ? 1535 HOH A O 1 HETATM 7742 O O . HOH H 4 . ? 25.346 111.666 29.636 1.00 28.41 ? 1536 HOH A O 1 HETATM 7743 O O . HOH H 4 . ? 34.989 108.991 18.839 1.00 42.67 ? 1537 HOH A O 1 HETATM 7744 O O . HOH H 4 . ? 36.377 116.184 47.793 1.00 35.79 ? 1538 HOH A O 1 HETATM 7745 O O . HOH H 4 . ? 51.797 75.859 17.972 1.00 51.31 ? 1539 HOH A O 1 HETATM 7746 O O . HOH H 4 . ? 30.317 97.814 5.231 1.00 32.60 ? 1540 HOH A O 1 HETATM 7747 O O . HOH H 4 . ? 43.804 120.472 32.493 1.00 36.05 ? 1541 HOH A O 1 HETATM 7748 O O . HOH H 4 . ? 71.918 102.342 -1.523 1.00 36.26 ? 1542 HOH A O 1 HETATM 7749 O O . HOH H 4 . ? 55.288 66.480 7.212 1.00 44.90 ? 1543 HOH A O 1 HETATM 7750 O O . HOH H 4 . ? 90.889 110.116 22.954 1.00 38.19 ? 1544 HOH A O 1 HETATM 7751 O O . HOH H 4 . ? 47.907 126.765 24.332 1.00 34.28 ? 1545 HOH A O 1 HETATM 7752 O O . HOH H 4 . ? 48.633 80.620 -9.214 1.00 40.71 ? 1546 HOH A O 1 HETATM 7753 O O . HOH H 4 . ? 61.021 109.846 -13.708 1.00 35.27 ? 1547 HOH A O 1 HETATM 7754 O O . HOH H 4 . ? 39.951 98.257 -20.738 1.00 34.38 ? 1548 HOH A O 1 HETATM 7755 O O . HOH H 4 . ? 21.218 84.148 20.893 1.00 40.15 ? 1549 HOH A O 1 HETATM 7756 O O . HOH H 4 . ? 37.247 102.956 2.952 1.00 44.66 ? 1550 HOH A O 1 HETATM 7757 O O . HOH H 4 . ? 38.183 104.889 0.592 1.00 52.25 ? 1551 HOH A O 1 HETATM 7758 O O . HOH H 4 . ? 41.040 105.273 1.700 1.00 39.27 ? 1552 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 ? ? ? A . n A 1 2 ALA 2 2 ? ? ? A . n A 1 3 GLU 3 3 ? ? ? A . n A 1 4 CYS 4 4 ? ? ? A . n A 1 5 PRO 5 5 ? ? ? A . n A 1 6 VAL 6 6 ? ? ? A . n A 1 7 VAL 7 7 7 VAL VAL A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 GLU 9 9 9 GLU GLU A . n A 1 10 LEU 10 10 10 LEU LEU A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 ARG 12 12 12 ARG ARG A . n A 1 13 ILE 13 13 13 ILE ILE A . n A 1 14 ASN 14 14 14 ASN ASN A . n A 1 15 CYS 15 15 15 CYS CYS A . n A 1 16 ILE 16 16 16 ILE ILE A . n A 1 17 PRO 17 17 17 PRO PRO A . n A 1 18 ASP 18 18 18 ASP ASP A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 PRO 20 20 20 PRO PRO A . n A 1 21 PRO 21 21 21 PRO PRO A . n A 1 22 THR 22 22 22 THR THR A . n A 1 23 LYS 23 23 23 LYS LYS A . n A 1 24 ALA 24 24 24 ALA ALA A . n A 1 25 THR 25 25 25 THR THR A . n A 1 26 CYS 26 26 26 CYS CYS A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 GLN 28 28 28 GLN GLN A . n A 1 29 ARG 29 29 29 ARG ARG A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 CYS 32 32 32 CYS CYS A . n A 1 33 TRP 33 33 33 TRP TRP A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 PRO 35 35 35 PRO PRO A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 ALA 38 38 38 ALA ALA A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 SER 40 40 40 SER SER A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 TRP 43 43 43 TRP TRP A . n A 1 44 CYS 44 44 44 CYS CYS A . n A 1 45 TYR 45 45 45 TYR TYR A . n A 1 46 TYR 46 46 46 TYR TYR A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 ASN 49 49 49 ASN ASN A . n A 1 50 HIS 50 50 50 HIS HIS A . n A 1 51 SER 51 51 51 SER SER A . n A 1 52 TYR 52 52 52 TYR TYR A . n A 1 53 HIS 53 53 53 HIS HIS A . n A 1 54 VAL 54 54 54 VAL VAL A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 LEU 58 58 58 LEU LEU A . n A 1 59 VAL 59 59 59 VAL VAL A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 THR 61 61 61 THR THR A . n A 1 62 ASN 62 62 62 ASN ASN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 PHE 65 65 65 PHE PHE A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ALA 67 67 67 ALA ALA A . n A 1 68 ARG 68 68 68 ARG ARG A . n A 1 69 LEU 69 69 69 LEU LEU A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 ASN 71 71 71 ASN ASN A . n A 1 72 LEU 72 72 72 LEU LEU A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 SER 74 74 74 SER SER A . n A 1 75 SER 75 75 75 SER SER A . n A 1 76 PRO 76 76 76 PRO PRO A . n A 1 77 VAL 77 77 77 VAL VAL A . n A 1 78 PHE 78 78 78 PHE PHE A . n A 1 79 GLY 79 79 79 GLY GLY A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 ASN 81 81 81 ASN ASN A . n A 1 82 VAL 82 82 82 VAL VAL A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 LEU 86 86 86 LEU LEU A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 THR 88 88 88 THR THR A . n A 1 89 ALA 89 89 89 ALA ALA A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 TYR 91 91 91 TYR TYR A . n A 1 92 GLN 92 92 92 GLN GLN A . n A 1 93 THR 93 93 93 THR THR A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 ASN 95 95 95 ASN ASN A . n A 1 96 ARG 96 96 96 ARG ARG A . n A 1 97 PHE 97 97 97 PHE PHE A . n A 1 98 HIS 98 98 98 HIS HIS A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 LYS 100 100 100 LYS LYS A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 THR 102 102 102 THR THR A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 ARG 108 108 108 ARG ARG A . n A 1 109 PHE 109 109 109 PHE PHE A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 PRO 112 112 112 PRO PRO A . n A 1 113 HIS 113 113 113 HIS HIS A . n A 1 114 GLU 114 114 114 GLU GLU A . n A 1 115 HIS 115 115 115 HIS HIS A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 GLN 117 117 117 GLN GLN A . n A 1 118 SER 118 118 118 SER SER A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 ASN 122 122 122 ASN ASN A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 ALA 124 124 124 ALA ALA A . n A 1 125 ALA 125 125 125 ALA ALA A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 TYR 129 129 129 TYR TYR A . n A 1 130 GLN 130 130 130 GLN GLN A . n A 1 131 VAL 131 131 131 VAL VAL A . n A 1 132 GLU 132 132 132 GLU GLU A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 GLN 136 136 136 GLN GLN A . n A 1 137 PRO 137 137 137 PRO PRO A . n A 1 138 PHE 138 138 138 PHE PHE A . n A 1 139 SER 139 139 139 SER SER A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 LYS 141 141 141 LYS LYS A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 THR 143 143 143 THR THR A . n A 1 144 ARG 144 144 144 ARG ARG A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 ASN 147 147 147 ASN ASN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 ARG 149 149 149 ARG ARG A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 SER 154 154 154 SER SER A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 ILE 156 156 156 ILE ILE A . n A 1 157 GLY 157 157 157 GLY GLY A . n A 1 158 PRO 158 158 158 PRO PRO A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LEU 160 160 160 LEU LEU A . n A 1 161 PHE 161 161 161 PHE PHE A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 ASP 163 163 163 ASP ASP A . n A 1 164 GLN 164 164 164 GLN GLN A . n A 1 165 PHE 165 165 165 PHE PHE A . n A 1 166 LEU 166 166 166 LEU LEU A . n A 1 167 GLN 167 167 167 GLN GLN A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 THR 170 170 170 THR THR A . n A 1 171 ARG 171 171 171 ARG ARG A . n A 1 172 LEU 172 172 172 LEU LEU A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 THR 175 175 175 THR THR A . n A 1 176 ASN 176 176 176 ASN ASN A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TYR 178 178 178 TYR TYR A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLY 181 181 181 GLY GLY A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 HIS 183 183 183 HIS HIS A . n A 1 184 VAL 184 184 184 VAL VAL A . n A 1 185 HIS 185 185 185 HIS HIS A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 GLN 187 187 187 GLN GLN A . n A 1 188 TYR 188 188 188 TYR TYR A . n A 1 189 ARG 189 189 189 ARG ARG A . n A 1 190 HIS 190 190 190 HIS HIS A . n A 1 191 ASP 191 191 191 ASP ASP A . n A 1 192 MET 192 192 192 MET MET A . n A 1 193 ASN 193 193 193 ASN ASN A . n A 1 194 TRP 194 194 194 TRP TRP A . n A 1 195 LYS 195 195 195 LYS LYS A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 TRP 197 197 197 TRP TRP A . n A 1 198 PRO 198 198 198 PRO PRO A . n A 1 199 ILE 199 199 199 ILE ILE A . n A 1 200 PHE 200 200 200 PHE PHE A . n A 1 201 ASN 201 201 201 ASN ASN A . n A 1 202 ARG 202 202 202 ARG ARG A . n A 1 203 ASP 203 203 203 ASP ASP A . n A 1 204 THR 204 204 204 THR THR A . n A 1 205 THR 205 205 205 THR THR A . n A 1 206 PRO 206 206 206 PRO PRO A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 GLY 208 208 208 GLY GLY A . n A 1 209 ASN 209 209 209 ASN ASN A . n A 1 210 GLY 210 210 210 GLY GLY A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 ASN 212 212 212 ASN ASN A . n A 1 213 LEU 213 213 213 LEU LEU A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 GLY 215 215 215 GLY GLY A . n A 1 216 ALA 216 216 216 ALA ALA A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 PHE 219 219 219 PHE PHE A . n A 1 220 PHE 220 220 220 PHE PHE A . n A 1 221 LEU 221 221 221 LEU LEU A . n A 1 222 CYS 222 222 222 CYS CYS A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 GLU 224 224 224 GLU GLU A . n A 1 225 ASP 225 225 225 ASP ASP A . n A 1 226 ALA 226 226 226 ALA ALA A . n A 1 227 SER 227 227 227 SER SER A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 PHE 231 231 231 PHE PHE A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 PHE 234 234 234 PHE PHE A . n A 1 235 LEU 235 235 235 LEU LEU A . n A 1 236 MET 236 236 236 MET MET A . n A 1 237 ASN 237 237 237 ASN ASN A . n A 1 238 SER 238 238 238 SER SER A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 ALA 240 240 240 ALA ALA A . n A 1 241 MET 241 241 241 MET MET A . n A 1 242 GLU 242 242 242 GLU GLU A . n A 1 243 VAL 243 243 243 VAL VAL A . n A 1 244 VAL 244 244 244 VAL VAL A . n A 1 245 LEU 245 245 245 LEU LEU A . n A 1 246 GLN 246 246 246 GLN GLN A . n A 1 247 PRO 247 247 247 PRO PRO A . n A 1 248 ALA 248 248 248 ALA ALA A . n A 1 249 PRO 249 249 249 PRO PRO A . n A 1 250 ALA 250 250 250 ALA ALA A . n A 1 251 ILE 251 251 251 ILE ILE A . n A 1 252 THR 252 252 252 THR THR A . n A 1 253 TYR 253 253 253 TYR TYR A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 THR 255 255 255 THR THR A . n A 1 256 ILE 256 256 256 ILE ILE A . n A 1 257 GLY 257 257 257 GLY GLY A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 ILE 259 259 259 ILE ILE A . n A 1 260 LEU 260 260 260 LEU LEU A . n A 1 261 ASP 261 261 261 ASP ASP A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 TYR 263 263 263 TYR TYR A . n A 1 264 VAL 264 264 264 VAL VAL A . n A 1 265 PHE 265 265 265 PHE PHE A . n A 1 266 LEU 266 266 266 LEU LEU A . n A 1 267 GLY 267 267 267 GLY GLY A . n A 1 268 ASN 268 268 268 ASN ASN A . n A 1 269 THR 269 269 269 THR THR A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 GLN 272 272 272 GLN GLN A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 GLN 275 275 275 GLN GLN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 TYR 277 277 277 TYR TYR A . n A 1 278 LEU 278 278 278 LEU LEU A . n A 1 279 GLU 279 279 279 GLU GLU A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 ILE 281 281 281 ILE ILE A . n A 1 282 GLY 282 282 282 GLY GLY A . n A 1 283 ARG 283 283 283 ARG ARG A . n A 1 284 PRO 284 284 284 PRO PRO A . n A 1 285 ALA 285 285 285 ALA ALA A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 SER 288 288 288 SER SER A . n A 1 289 TYR 289 289 289 TYR TYR A . n A 1 290 TRP 290 290 290 TRP TRP A . n A 1 291 ALA 291 291 291 ALA ALA A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 PHE 294 294 294 PHE PHE A . n A 1 295 HIS 295 295 295 HIS HIS A . n A 1 296 LEU 296 296 296 LEU LEU A . n A 1 297 SER 297 297 297 SER SER A . n A 1 298 ARG 298 298 298 ARG ARG A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 GLU 300 300 300 GLU GLU A . n A 1 301 TYR 301 301 301 TYR TYR A . n A 1 302 GLY 302 302 302 GLY GLY A . n A 1 303 THR 303 303 303 THR THR A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 ASP 305 305 305 ASP ASP A . n A 1 306 ASN 306 306 306 ASN ASN A . n A 1 307 MET 307 307 307 MET MET A . n A 1 308 ARG 308 308 308 ARG ARG A . n A 1 309 GLU 309 309 309 GLU GLU A . n A 1 310 VAL 310 310 310 VAL VAL A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 GLU 312 312 312 GLU GLU A . n A 1 313 ARG 313 313 313 ARG ARG A . n A 1 314 ASN 314 314 314 ASN ASN A . n A 1 315 ARG 315 315 315 ARG ARG A . n A 1 316 ALA 316 316 316 ALA ALA A . n A 1 317 ALA 317 317 317 ALA ALA A . n A 1 318 GLN 318 318 318 GLN GLN A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 PRO 320 320 320 PRO PRO A . n A 1 321 TYR 321 321 321 TYR TYR A . n A 1 322 ASP 322 322 322 ASP ASP A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 GLN 324 324 324 GLN GLN A . n A 1 325 HIS 325 325 325 HIS HIS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 ASP 327 327 327 ASP ASP A . n A 1 328 ILE 328 328 328 ILE ILE A . n A 1 329 ASP 329 329 329 ASP ASP A . n A 1 330 TYR 330 330 330 TYR TYR A . n A 1 331 MET 331 331 331 MET MET A . n A 1 332 ASP 332 332 332 ASP ASP A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 ARG 334 334 334 ARG ARG A . n A 1 335 ARG 335 335 335 ARG ARG A . n A 1 336 ASP 336 336 336 ASP ASP A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 THR 338 338 338 THR THR A . n A 1 339 TYR 339 339 339 TYR TYR A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 SER 341 341 341 SER SER A . n A 1 342 VAL 342 342 342 VAL VAL A . n A 1 343 ASP 343 343 343 ASP ASP A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLY 346 346 346 GLY GLY A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 PRO 348 348 348 PRO PRO A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 VAL 351 351 351 VAL VAL A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 GLU 353 353 353 GLU GLU A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 HIS 355 355 355 HIS HIS A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 ASN 357 357 357 ASN ASN A . n A 1 358 GLY 358 358 358 GLY GLY A . n A 1 359 GLN 359 359 359 GLN GLN A . n A 1 360 LYS 360 360 360 LYS LYS A . n A 1 361 LEU 361 361 361 LEU LEU A . n A 1 362 VAL 362 362 362 VAL VAL A . n A 1 363 ILE 363 363 363 ILE ILE A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 VAL 365 365 365 VAL VAL A . n A 1 366 ASP 366 366 366 ASP ASP A . n A 1 367 PRO 367 367 367 PRO PRO A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 SER 370 370 370 SER SER A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 ASN 372 372 372 ASN ASN A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 SER 375 375 375 SER SER A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 LYS 377 377 377 LYS LYS A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 TYR 379 379 379 TYR TYR A . n A 1 380 GLY 380 380 380 GLY GLY A . n A 1 381 PRO 381 381 381 PRO PRO A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 ASP 383 383 383 ASP ASP A . n A 1 384 ARG 384 384 384 ARG ARG A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 SER 386 386 386 SER SER A . n A 1 387 ASP 387 387 387 ASP ASP A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 LYS 389 389 389 LYS LYS A . n A 1 390 ILE 390 390 390 ILE ILE A . n A 1 391 TRP 391 391 391 TRP TRP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 ASN 393 393 393 ASN ASN A . n A 1 394 SER 394 394 394 SER SER A . n A 1 395 SER 395 395 395 SER SER A . n A 1 396 ASP 396 396 396 ASP ASP A . n A 1 397 GLY 397 397 397 GLY GLY A . n A 1 398 VAL 398 398 398 VAL VAL A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 PRO 400 400 400 PRO PRO A . n A 1 401 LEU 401 401 401 LEU LEU A . n A 1 402 ILE 402 402 402 ILE ILE A . n A 1 403 GLY 403 403 403 GLY GLY A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 VAL 405 405 405 VAL VAL A . n A 1 406 TRP 406 406 406 TRP TRP A . n A 1 407 PRO 407 407 407 PRO PRO A . n A 1 408 GLY 408 408 408 GLY GLY A . n A 1 409 GLN 409 409 409 GLN GLN A . n A 1 410 THR 410 410 410 THR THR A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 PHE 412 412 412 PHE PHE A . n A 1 413 PRO 413 413 413 PRO PRO A . n A 1 414 ASP 414 414 414 ASP ASP A . n A 1 415 TYR 415 415 415 TYR TYR A . n A 1 416 THR 416 416 416 THR THR A . n A 1 417 ASN 417 417 417 ASN ASN A . n A 1 418 PRO 418 418 418 PRO PRO A . n A 1 419 ASN 419 419 419 ASN ASN A . n A 1 420 CYS 420 420 420 CYS CYS A . n A 1 421 ALA 421 421 421 ALA ALA A . n A 1 422 VAL 422 422 422 VAL VAL A . n A 1 423 TRP 423 423 423 TRP TRP A . n A 1 424 TRP 424 424 424 TRP TRP A . n A 1 425 THR 425 425 425 THR THR A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 GLU 427 427 427 GLU GLU A . n A 1 428 PHE 428 428 428 PHE PHE A . n A 1 429 GLU 429 429 429 GLU GLU A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 PHE 431 431 431 PHE PHE A . n A 1 432 HIS 432 432 432 HIS HIS A . n A 1 433 ASN 433 433 433 ASN ASN A . n A 1 434 GLN 434 434 434 GLN GLN A . n A 1 435 VAL 435 435 435 VAL VAL A . n A 1 436 GLU 436 436 436 GLU GLU A . n A 1 437 PHE 437 437 437 PHE PHE A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 ILE 440 440 440 ILE ILE A . n A 1 441 TRP 441 441 441 TRP TRP A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 MET 444 444 444 MET MET A . n A 1 445 ASN 445 445 445 ASN ASN A . n A 1 446 GLU 446 446 446 GLU GLU A . n A 1 447 VAL 447 447 447 VAL VAL A . n A 1 448 SER 448 448 448 SER SER A . n A 1 449 ASN 449 449 449 ASN ASN A . n A 1 450 PHE 450 450 450 PHE PHE A . n A 1 451 VAL 451 451 451 VAL VAL A . n A 1 452 ASP 452 452 452 ASP ASP A . n A 1 453 GLY 453 453 453 GLY GLY A . n A 1 454 SER 454 454 454 SER SER A . n A 1 455 VAL 455 455 455 VAL VAL A . n A 1 456 SER 456 456 456 SER SER A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 CYS 458 458 458 CYS CYS A . n A 1 459 SER 459 459 459 SER SER A . n A 1 460 THR 460 460 460 THR THR A . n A 1 461 ASN 461 461 461 ASN ASN A . n A 1 462 ASN 462 462 462 ASN ASN A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 ASN 464 464 464 ASN ASN A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 PRO 466 466 466 PRO PRO A . n A 1 467 PRO 467 467 467 PRO PRO A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 THR 469 469 469 THR THR A . n A 1 470 PRO 470 470 470 PRO PRO A . n A 1 471 ARG 471 471 471 ARG ARG A . n A 1 472 ILE 472 472 472 ILE ILE A . n A 1 473 LEU 473 473 473 LEU LEU A . n A 1 474 ASP 474 474 474 ASP ASP A . n A 1 475 GLY 475 475 475 GLY GLY A . n A 1 476 TYR 476 476 476 TYR TYR A . n A 1 477 LEU 477 477 477 LEU LEU A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 CYS 479 479 479 CYS CYS A . n A 1 480 LYS 480 480 480 LYS LYS A . n A 1 481 THR 481 481 481 THR THR A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 CYS 483 483 483 CYS CYS A . n A 1 484 MET 484 484 484 MET MET A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 ALA 486 486 486 ALA ALA A . n A 1 487 VAL 487 487 487 VAL VAL A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 HIS 489 489 489 HIS HIS A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 GLY 491 491 491 GLY GLY A . n A 1 492 LYS 492 492 492 LYS LYS A . n A 1 493 GLN 493 493 493 GLN GLN A . n A 1 494 TYR 494 494 494 TYR TYR A . n A 1 495 ASP 495 495 495 ASP ASP A . n A 1 496 ILE 496 496 496 ILE ILE A . n A 1 497 HIS 497 497 497 HIS HIS A . n A 1 498 ASN 498 498 498 ASN ASN A . n A 1 499 LEU 499 499 499 LEU LEU A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 GLY 501 501 501 GLY GLY A . n A 1 502 TYR 502 502 502 TYR TYR A . n A 1 503 SER 503 503 503 SER SER A . n A 1 504 MET 504 504 504 MET MET A . n A 1 505 ALA 505 505 505 ALA ALA A . n A 1 506 VAL 506 506 506 VAL VAL A . n A 1 507 ALA 507 507 507 ALA ALA A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ALA 509 509 509 ALA ALA A . n A 1 510 GLU 510 510 510 GLU GLU A . n A 1 511 ALA 511 511 511 ALA ALA A . n A 1 512 ALA 512 512 512 ALA ALA A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 THR 514 514 514 THR THR A . n A 1 515 VAL 515 515 515 VAL VAL A . n A 1 516 PHE 516 516 516 PHE PHE A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASN 518 518 518 ASN ASN A . n A 1 519 LYS 519 519 519 LYS LYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 SER 521 521 521 SER SER A . n A 1 522 PHE 522 522 522 PHE PHE A . n A 1 523 ILE 523 523 523 ILE ILE A . n A 1 524 LEU 524 524 524 LEU LEU A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 ARG 526 526 526 ARG ARG A . n A 1 527 SER 527 527 527 SER SER A . n A 1 528 THR 528 528 528 THR THR A . n A 1 529 PHE 529 529 529 PHE PHE A . n A 1 530 ALA 530 530 530 ALA ALA A . n A 1 531 GLY 531 531 531 GLY GLY A . n A 1 532 SER 532 532 532 SER SER A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 LYS 534 534 534 LYS LYS A . n A 1 535 PHE 535 535 535 PHE PHE A . n A 1 536 ALA 536 536 536 ALA ALA A . n A 1 537 ALA 537 537 537 ALA ALA A . n A 1 538 HIS 538 538 538 HIS HIS A . n A 1 539 TRP 539 539 539 TRP TRP A . n A 1 540 LEU 540 540 540 LEU LEU A . n A 1 541 GLY 541 541 541 GLY GLY A . n A 1 542 ASP 542 542 542 ASP ASP A . n A 1 543 ASN 543 543 543 ASN ASN A . n A 1 544 THR 544 544 544 THR THR A . n A 1 545 ALA 545 545 545 ALA ALA A . n A 1 546 THR 546 546 546 THR THR A . n A 1 547 TRP 547 547 547 TRP TRP A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ASP 549 549 549 ASP ASP A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 ARG 551 551 551 ARG ARG A . n A 1 552 TRP 552 552 552 TRP TRP A . n A 1 553 SER 553 553 553 SER SER A . n A 1 554 ILE 554 554 554 ILE ILE A . n A 1 555 PRO 555 555 555 PRO PRO A . n A 1 556 GLY 556 556 556 GLY GLY A . n A 1 557 VAL 557 557 557 VAL VAL A . n A 1 558 LEU 558 558 558 LEU LEU A . n A 1 559 GLU 559 559 559 GLU GLU A . n A 1 560 PHE 560 560 560 PHE PHE A . n A 1 561 ASN 561 561 561 ASN ASN A . n A 1 562 LEU 562 562 562 LEU LEU A . n A 1 563 PHE 563 563 563 PHE PHE A . n A 1 564 GLY 564 564 564 GLY GLY A . n A 1 565 ILE 565 565 565 ILE ILE A . n A 1 566 PRO 566 566 566 PRO PRO A . n A 1 567 MET 567 567 567 MET MET A . n A 1 568 VAL 568 568 568 VAL VAL A . n A 1 569 GLY 569 569 569 GLY GLY A . n A 1 570 PRO 570 570 570 PRO PRO A . n A 1 571 ASP 571 571 571 ASP ASP A . n A 1 572 ILE 572 572 572 ILE ILE A . n A 1 573 CYS 573 573 573 CYS CYS A . n A 1 574 GLY 574 574 574 GLY GLY A . n A 1 575 PHE 575 575 575 PHE PHE A . n A 1 576 ALA 576 576 576 ALA ALA A . n A 1 577 LEU 577 577 577 LEU LEU A . n A 1 578 ASP 578 578 578 ASP ASP A . n A 1 579 THR 579 579 579 THR THR A . n A 1 580 PRO 580 580 580 PRO PRO A . n A 1 581 GLU 581 581 581 GLU GLU A . n A 1 582 GLU 582 582 582 GLU GLU A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 CYS 584 584 584 CYS CYS A . n A 1 585 ARG 585 585 585 ARG ARG A . n A 1 586 ARG 586 586 586 ARG ARG A . n A 1 587 TRP 587 587 587 TRP TRP A . n A 1 588 MET 588 588 588 MET MET A . n A 1 589 GLN 589 589 589 GLN GLN A . n A 1 590 LEU 590 590 590 LEU LEU A . n A 1 591 GLY 591 591 591 GLY GLY A . n A 1 592 ALA 592 592 592 ALA ALA A . n A 1 593 PHE 593 593 593 PHE PHE A . n A 1 594 TYR 594 594 594 TYR TYR A . n A 1 595 PRO 595 595 595 PRO PRO A . n A 1 596 PHE 596 596 596 PHE PHE A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 ARG 598 598 598 ARG ARG A . n A 1 599 ASN 599 599 599 ASN ASN A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASN 601 601 601 ASN ASN A . n A 1 602 GLY 602 602 602 GLY GLY A . n A 1 603 GLN 603 603 603 GLN GLN A . n A 1 604 GLY 604 604 604 GLY GLY A . n A 1 605 TYR 605 605 605 TYR TYR A . n A 1 606 LYS 606 606 606 LYS LYS A . n A 1 607 ASP 607 607 607 ASP ASP A . n A 1 608 GLN 608 608 608 GLN GLN A . n A 1 609 ASP 609 609 609 ASP ASP A . n A 1 610 PRO 610 610 610 PRO PRO A . n A 1 611 ALA 611 611 611 ALA ALA A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 PHE 613 613 613 PHE PHE A . n A 1 614 GLY 614 614 614 GLY GLY A . n A 1 615 ALA 615 615 615 ALA ALA A . n A 1 616 ASP 616 616 616 ASP ASP A . n A 1 617 SER 617 617 617 SER SER A . n A 1 618 LEU 618 618 618 LEU LEU A . n A 1 619 LEU 619 619 619 LEU LEU A . n A 1 620 LEU 620 620 620 LEU LEU A . n A 1 621 ASN 621 621 621 ASN ASN A . n A 1 622 SER 622 622 622 SER SER A . n A 1 623 SER 623 623 623 SER SER A . n A 1 624 ARG 624 624 624 ARG ARG A . n A 1 625 HIS 625 625 625 HIS HIS A . n A 1 626 TYR 626 626 626 TYR TYR A . n A 1 627 LEU 627 627 627 LEU LEU A . n A 1 628 ASN 628 628 628 ASN ASN A . n A 1 629 ILE 629 629 629 ILE ILE A . n A 1 630 ARG 630 630 630 ARG ARG A . n A 1 631 TYR 631 631 631 TYR TYR A . n A 1 632 THR 632 632 632 THR THR A . n A 1 633 LEU 633 633 633 LEU LEU A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 PRO 635 635 635 PRO PRO A . n A 1 636 TYR 636 636 636 TYR TYR A . n A 1 637 LEU 637 637 637 LEU LEU A . n A 1 638 TYR 638 638 638 TYR TYR A . n A 1 639 THR 639 639 639 THR THR A . n A 1 640 LEU 640 640 640 LEU LEU A . n A 1 641 PHE 641 641 641 PHE PHE A . n A 1 642 PHE 642 642 642 PHE PHE A . n A 1 643 ARG 643 643 643 ARG ARG A . n A 1 644 ALA 644 644 644 ALA ALA A . n A 1 645 HIS 645 645 645 HIS HIS A . n A 1 646 SER 646 646 646 SER SER A . n A 1 647 ARG 647 647 647 ARG ARG A . n A 1 648 GLY 648 648 648 GLY GLY A . n A 1 649 ASP 649 649 649 ASP ASP A . n A 1 650 THR 650 650 650 THR THR A . n A 1 651 VAL 651 651 651 VAL VAL A . n A 1 652 ALA 652 652 652 ALA ALA A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 PRO 654 654 654 PRO PRO A . n A 1 655 LEU 655 655 655 LEU LEU A . n A 1 656 LEU 656 656 656 LEU LEU A . n A 1 657 HIS 657 657 657 HIS HIS A . n A 1 658 GLU 658 658 658 GLU GLU A . n A 1 659 PHE 659 659 659 PHE PHE A . n A 1 660 TYR 660 660 660 TYR TYR A . n A 1 661 GLU 661 661 661 GLU GLU A . n A 1 662 ASP 662 662 662 ASP ASP A . n A 1 663 ASN 663 663 663 ASN ASN A . n A 1 664 SER 664 664 664 SER SER A . n A 1 665 THR 665 665 665 THR THR A . n A 1 666 TRP 666 666 666 TRP TRP A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 HIS 669 669 669 HIS HIS A . n A 1 670 GLN 670 670 670 GLN GLN A . n A 1 671 GLN 671 671 671 GLN GLN A . n A 1 672 PHE 672 672 672 PHE PHE A . n A 1 673 LEU 673 673 673 LEU LEU A . n A 1 674 TRP 674 674 674 TRP TRP A . n A 1 675 GLY 675 675 675 GLY GLY A . n A 1 676 PRO 676 676 676 PRO PRO A . n A 1 677 GLY 677 677 677 GLY GLY A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 LEU 679 679 679 LEU LEU A . n A 1 680 ILE 680 680 680 ILE ILE A . n A 1 681 THR 681 681 681 THR THR A . n A 1 682 PRO 682 682 682 PRO PRO A . n A 1 683 VAL 683 683 683 VAL VAL A . n A 1 684 LEU 684 684 684 LEU LEU A . n A 1 685 ASP 685 685 685 ASP ASP A . n A 1 686 GLU 686 686 686 GLU GLU A . n A 1 687 GLY 687 687 687 GLY GLY A . n A 1 688 ALA 688 688 688 ALA ALA A . n A 1 689 GLU 689 689 689 GLU GLU A . n A 1 690 LYS 690 690 690 LYS LYS A . n A 1 691 VAL 691 691 691 VAL VAL A . n A 1 692 MET 692 692 692 MET MET A . n A 1 693 ALA 693 693 693 ALA ALA A . n A 1 694 TYR 694 694 694 TYR TYR A . n A 1 695 VAL 695 695 695 VAL VAL A . n A 1 696 PRO 696 696 696 PRO PRO A . n A 1 697 ASP 697 697 697 ASP ASP A . n A 1 698 ALA 698 698 698 ALA ALA A . n A 1 699 VAL 699 699 699 VAL VAL A . n A 1 700 TRP 700 700 700 TRP TRP A . n A 1 701 TYR 701 701 701 TYR TYR A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 TYR 703 703 703 TYR TYR A . n A 1 704 GLU 704 704 704 GLU GLU A . n A 1 705 THR 705 705 705 THR THR A . n A 1 706 GLY 706 706 706 GLY GLY A . n A 1 707 SER 707 707 707 SER SER A . n A 1 708 GLN 708 708 708 GLN GLN A . n A 1 709 VAL 709 709 709 VAL VAL A . n A 1 710 ARG 710 710 710 ARG ARG A . n A 1 711 TRP 711 711 711 TRP TRP A . n A 1 712 ARG 712 712 712 ARG ARG A . n A 1 713 LYS 713 713 713 LYS LYS A . n A 1 714 GLN 714 714 714 GLN GLN A . n A 1 715 LYS 715 715 715 LYS LYS A . n A 1 716 VAL 716 716 716 VAL VAL A . n A 1 717 GLU 717 717 717 GLU GLU A . n A 1 718 MET 718 718 718 MET MET A . n A 1 719 GLU 719 719 719 GLU GLU A . n A 1 720 LEU 720 720 720 LEU LEU A . n A 1 721 PRO 721 721 721 PRO PRO A . n A 1 722 GLY 722 722 722 GLY GLY A . n A 1 723 ASP 723 723 723 ASP ASP A . n A 1 724 LYS 724 724 724 LYS LYS A . n A 1 725 ILE 725 725 725 ILE ILE A . n A 1 726 GLY 726 726 726 GLY GLY A . n A 1 727 LEU 727 727 727 LEU LEU A . n A 1 728 HIS 728 728 728 HIS HIS A . n A 1 729 LEU 729 729 729 LEU LEU A . n A 1 730 ARG 730 730 730 ARG ARG A . n A 1 731 GLY 731 731 731 GLY GLY A . n A 1 732 GLY 732 732 732 GLY GLY A . n A 1 733 TYR 733 733 733 TYR TYR A . n A 1 734 ILE 734 734 734 ILE ILE A . n A 1 735 PHE 735 735 735 PHE PHE A . n A 1 736 PRO 736 736 736 PRO PRO A . n A 1 737 THR 737 737 737 THR THR A . n A 1 738 GLN 738 738 738 GLN GLN A . n A 1 739 GLN 739 739 739 GLN GLN A . n A 1 740 PRO 740 740 740 PRO PRO A . n A 1 741 ASN 741 741 741 ASN ASN A . n A 1 742 THR 742 742 742 THR THR A . n A 1 743 THR 743 743 743 THR THR A . n A 1 744 THR 744 744 744 THR THR A . n A 1 745 LEU 745 745 745 LEU LEU A . n A 1 746 ALA 746 746 746 ALA ALA A . n A 1 747 SER 747 747 747 SER SER A . n A 1 748 ARG 748 748 748 ARG ARG A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 ASN 750 750 750 ASN ASN A . n A 1 751 PRO 751 751 751 PRO PRO A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLY 753 753 753 GLY GLY A . n A 1 754 LEU 754 754 754 LEU LEU A . n A 1 755 ILE 755 755 755 ILE ILE A . n A 1 756 ILE 756 756 756 ILE ILE A . n A 1 757 ALA 757 757 757 ALA ALA A . n A 1 758 LEU 758 758 758 LEU LEU A . n A 1 759 ASP 759 759 759 ASP ASP A . n A 1 760 GLU 760 760 760 GLU GLU A . n A 1 761 ASN 761 761 761 ASN ASN A . n A 1 762 LYS 762 762 762 LYS LYS A . n A 1 763 GLU 763 763 763 GLU GLU A . n A 1 764 ALA 764 764 764 ALA ALA A . n A 1 765 LYS 765 765 765 LYS LYS A . n A 1 766 GLY 766 766 766 GLY GLY A . n A 1 767 GLU 767 767 767 GLU GLU A . n A 1 768 LEU 768 768 768 LEU LEU A . n A 1 769 PHE 769 769 769 PHE PHE A . n A 1 770 TRP 770 770 770 TRP TRP A . n A 1 771 ASP 771 771 771 ASP ASP A . n A 1 772 ASP 772 772 772 ASP ASP A . n A 1 773 GLY 773 773 773 GLY GLY A . n A 1 774 GLU 774 774 774 GLU GLU A . n A 1 775 THR 775 775 775 THR THR A . n A 1 776 LYS 776 776 776 LYS LYS A . n A 1 777 ASP 777 777 777 ASP ASP A . n A 1 778 THR 778 778 778 THR THR A . n A 1 779 VAL 779 779 779 VAL VAL A . n A 1 780 ALA 780 780 780 ALA ALA A . n A 1 781 ASN 781 781 781 ASN ASN A . n A 1 782 LYS 782 782 782 LYS LYS A . n A 1 783 VAL 783 783 783 VAL VAL A . n A 1 784 TYR 784 784 784 TYR TYR A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 LEU 786 786 786 LEU LEU A . n A 1 787 CYS 787 787 787 CYS CYS A . n A 1 788 GLU 788 788 788 GLU GLU A . n A 1 789 PHE 789 789 789 PHE PHE A . n A 1 790 SER 790 790 790 SER SER A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 THR 792 792 792 THR THR A . n A 1 793 GLN 793 793 793 GLN GLN A . n A 1 794 ASN 794 794 794 ASN ASN A . n A 1 795 ARG 795 795 795 ARG ARG A . n A 1 796 LEU 796 796 796 LEU LEU A . n A 1 797 GLU 797 797 797 GLU GLU A . n A 1 798 VAL 798 798 798 VAL VAL A . n A 1 799 ASN 799 799 799 ASN ASN A . n A 1 800 ILE 800 800 800 ILE ILE A . n A 1 801 SER 801 801 801 SER SER A . n A 1 802 GLN 802 802 802 GLN GLN A . n A 1 803 SER 803 803 803 SER SER A . n A 1 804 THR 804 804 804 THR THR A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 LYS 806 806 806 LYS LYS A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 PRO 808 808 808 PRO PRO A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 ASN 810 810 810 ASN ASN A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 ALA 812 812 812 ALA ALA A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ASN 814 814 814 ASN ASN A . n A 1 815 GLU 815 815 815 GLU GLU A . n A 1 816 ILE 816 816 816 ILE ILE A . n A 1 817 LYS 817 817 817 LYS LYS A . n A 1 818 ILE 818 818 818 ILE ILE A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 GLY 820 820 820 GLY GLY A . n A 1 821 THR 821 821 821 THR THR A . n A 1 822 GLU 822 822 822 GLU GLU A . n A 1 823 GLU 823 823 823 GLU GLU A . n A 1 824 PRO 824 824 824 PRO PRO A . n A 1 825 SER 825 825 825 SER SER A . n A 1 826 ASN 826 826 826 ASN ASN A . n A 1 827 VAL 827 827 827 VAL VAL A . n A 1 828 THR 828 828 828 THR THR A . n A 1 829 VAL 829 829 829 VAL VAL A . n A 1 830 LYS 830 830 830 LYS LYS A . n A 1 831 HIS 831 831 831 HIS HIS A . n A 1 832 ASN 832 832 832 ASN ASN A . n A 1 833 GLY 833 833 833 GLY GLY A . n A 1 834 VAL 834 834 834 VAL VAL A . n A 1 835 PRO 835 835 835 PRO PRO A . n A 1 836 SER 836 836 836 SER SER A . n A 1 837 GLN 837 837 ? ? ? A . n A 1 838 THR 838 838 838 THR THR A . n A 1 839 SER 839 839 839 SER SER A . n A 1 840 PRO 840 840 840 PRO PRO A . n A 1 841 THR 841 841 841 THR THR A . n A 1 842 VAL 842 842 842 VAL VAL A . n A 1 843 THR 843 843 843 THR THR A . n A 1 844 TYR 844 844 844 TYR TYR A . n A 1 845 ASP 845 845 845 ASP ASP A . n A 1 846 SER 846 846 846 SER SER A . n A 1 847 ASN 847 847 847 ASN ASN A . n A 1 848 LEU 848 848 848 LEU LEU A . n A 1 849 LYS 849 849 849 LYS LYS A . n A 1 850 VAL 850 850 850 VAL VAL A . n A 1 851 ALA 851 851 851 ALA ALA A . n A 1 852 ILE 852 852 852 ILE ILE A . n A 1 853 ILE 853 853 853 ILE ILE A . n A 1 854 THR 854 854 854 THR THR A . n A 1 855 ASP 855 855 855 ASP ASP A . n A 1 856 ILE 856 856 856 ILE ILE A . n A 1 857 ASP 857 857 857 ASP ASP A . n A 1 858 LEU 858 858 858 LEU LEU A . n A 1 859 LEU 859 859 859 LEU LEU A . n A 1 860 LEU 860 860 860 LEU LEU A . n A 1 861 GLY 861 861 861 GLY GLY A . n A 1 862 GLU 862 862 862 GLU GLU A . n A 1 863 ALA 863 863 863 ALA ALA A . n A 1 864 TYR 864 864 864 TYR TYR A . n A 1 865 THR 865 865 865 THR THR A . n A 1 866 VAL 866 866 866 VAL VAL A . n A 1 867 GLU 867 867 867 GLU GLU A . n A 1 868 TRP 868 868 868 TRP TRP A . n A 1 869 ALA 869 869 869 ALA ALA A . n A 1 870 HIS 870 870 870 HIS HIS A . n A 1 871 HIS 871 871 ? ? ? A . n A 1 872 HIS 872 872 ? ? ? A . n A 1 873 HIS 873 873 ? ? ? A . n A 1 874 HIS 874 874 ? ? ? A . n A 1 875 HIS 875 875 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 KTL 1 1001 1001 KTL KTL A . C 3 NAG 1 2001 2001 NAG NAG A . D 3 NAG 2 2002 2002 NAG NAG A . E 3 NAG 1 2003 2003 NAG NAG A . F 3 NAG 2 2004 2004 NAG NAG A . G 3 NAG 1 2005 2005 NAG NAG A . H 4 HOH 1 876 1 HOH HOH A . H 4 HOH 2 877 2 HOH HOH A . H 4 HOH 3 878 3 HOH HOH A . H 4 HOH 4 879 4 HOH HOH A . H 4 HOH 5 880 5 HOH HOH A . H 4 HOH 6 881 6 HOH HOH A . H 4 HOH 7 882 7 HOH HOH A . H 4 HOH 8 883 8 HOH HOH A . H 4 HOH 9 884 9 HOH HOH A . H 4 HOH 10 885 10 HOH HOH A . H 4 HOH 11 886 11 HOH HOH A . H 4 HOH 12 887 12 HOH HOH A . H 4 HOH 13 888 13 HOH HOH A . H 4 HOH 14 889 14 HOH HOH A . H 4 HOH 15 890 15 HOH HOH A . H 4 HOH 16 891 16 HOH HOH A . H 4 HOH 17 892 17 HOH HOH A . H 4 HOH 18 893 18 HOH HOH A . H 4 HOH 19 894 19 HOH HOH A . H 4 HOH 20 895 20 HOH HOH A . H 4 HOH 21 896 21 HOH HOH A . H 4 HOH 22 897 22 HOH HOH A . H 4 HOH 23 898 23 HOH HOH A . H 4 HOH 24 899 24 HOH HOH A . H 4 HOH 25 900 25 HOH HOH A . H 4 HOH 26 901 26 HOH HOH A . H 4 HOH 27 902 27 HOH HOH A . H 4 HOH 28 903 28 HOH HOH A . H 4 HOH 29 904 29 HOH HOH A . H 4 HOH 30 905 30 HOH HOH A . H 4 HOH 31 906 31 HOH HOH A . H 4 HOH 32 907 32 HOH HOH A . H 4 HOH 33 908 33 HOH HOH A . H 4 HOH 34 909 34 HOH HOH A . H 4 HOH 35 910 35 HOH HOH A . H 4 HOH 36 911 36 HOH HOH A . H 4 HOH 37 912 37 HOH HOH A . H 4 HOH 38 913 38 HOH HOH A . H 4 HOH 39 914 39 HOH HOH A . H 4 HOH 40 915 40 HOH HOH A . H 4 HOH 41 916 41 HOH HOH A . H 4 HOH 42 917 42 HOH HOH A . H 4 HOH 43 918 43 HOH HOH A . H 4 HOH 44 919 44 HOH HOH A . H 4 HOH 45 920 45 HOH HOH A . H 4 HOH 46 921 46 HOH HOH A . H 4 HOH 47 922 47 HOH HOH A . H 4 HOH 48 923 48 HOH HOH A . H 4 HOH 49 924 49 HOH HOH A . H 4 HOH 50 925 50 HOH HOH A . H 4 HOH 51 926 51 HOH HOH A . H 4 HOH 52 927 52 HOH HOH A . H 4 HOH 53 928 53 HOH HOH A . H 4 HOH 54 929 54 HOH HOH A . H 4 HOH 55 930 55 HOH HOH A . H 4 HOH 56 931 56 HOH HOH A . H 4 HOH 57 932 57 HOH HOH A . H 4 HOH 58 933 58 HOH HOH A . H 4 HOH 59 934 59 HOH HOH A . H 4 HOH 60 935 60 HOH HOH A . H 4 HOH 61 936 61 HOH HOH A . H 4 HOH 62 937 62 HOH HOH A . H 4 HOH 63 938 63 HOH HOH A . H 4 HOH 64 939 64 HOH HOH A . H 4 HOH 65 940 65 HOH HOH A . H 4 HOH 66 941 66 HOH HOH A . H 4 HOH 67 942 67 HOH HOH A . H 4 HOH 68 943 68 HOH HOH A . H 4 HOH 69 944 69 HOH HOH A . H 4 HOH 70 945 70 HOH HOH A . H 4 HOH 71 946 71 HOH HOH A . H 4 HOH 72 947 72 HOH HOH A . H 4 HOH 73 948 73 HOH HOH A . H 4 HOH 74 949 74 HOH HOH A . H 4 HOH 75 950 75 HOH HOH A . H 4 HOH 76 951 76 HOH HOH A . H 4 HOH 77 952 77 HOH HOH A . H 4 HOH 78 953 78 HOH HOH A . H 4 HOH 79 954 79 HOH HOH A . H 4 HOH 80 955 80 HOH HOH A . H 4 HOH 81 956 81 HOH HOH A . H 4 HOH 82 957 82 HOH HOH A . H 4 HOH 83 958 83 HOH HOH A . H 4 HOH 84 959 84 HOH HOH A . H 4 HOH 85 960 85 HOH HOH A . H 4 HOH 86 961 86 HOH HOH A . H 4 HOH 87 962 87 HOH HOH A . H 4 HOH 88 963 88 HOH HOH A . H 4 HOH 89 964 89 HOH HOH A . H 4 HOH 90 965 90 HOH HOH A . H 4 HOH 91 966 91 HOH HOH A . H 4 HOH 92 967 92 HOH HOH A . H 4 HOH 93 968 93 HOH HOH A . H 4 HOH 94 969 94 HOH HOH A . H 4 HOH 95 970 95 HOH HOH A . H 4 HOH 96 971 96 HOH HOH A . H 4 HOH 97 972 97 HOH HOH A . H 4 HOH 98 973 98 HOH HOH A . H 4 HOH 99 974 99 HOH HOH A . H 4 HOH 100 975 100 HOH HOH A . H 4 HOH 101 976 101 HOH HOH A . H 4 HOH 102 977 102 HOH HOH A . H 4 HOH 103 978 103 HOH HOH A . H 4 HOH 104 979 104 HOH HOH A . H 4 HOH 105 980 105 HOH HOH A . H 4 HOH 106 981 106 HOH HOH A . H 4 HOH 107 982 107 HOH HOH A . H 4 HOH 108 983 108 HOH HOH A . H 4 HOH 109 984 109 HOH HOH A . H 4 HOH 110 985 110 HOH HOH A . H 4 HOH 111 986 111 HOH HOH A . H 4 HOH 112 987 112 HOH HOH A . H 4 HOH 113 988 113 HOH HOH A . H 4 HOH 114 989 114 HOH HOH A . H 4 HOH 115 990 115 HOH HOH A . H 4 HOH 116 991 116 HOH HOH A . H 4 HOH 117 992 117 HOH HOH A . H 4 HOH 118 993 118 HOH HOH A . H 4 HOH 119 994 119 HOH HOH A . H 4 HOH 120 995 120 HOH HOH A . H 4 HOH 121 996 121 HOH HOH A . H 4 HOH 122 997 122 HOH HOH A . H 4 HOH 123 998 123 HOH HOH A . H 4 HOH 124 999 124 HOH HOH A . H 4 HOH 125 1000 125 HOH HOH A . H 4 HOH 126 1002 126 HOH HOH A . H 4 HOH 127 1003 127 HOH HOH A . H 4 HOH 128 1004 128 HOH HOH A . H 4 HOH 129 1005 129 HOH HOH A . H 4 HOH 130 1006 130 HOH HOH A . H 4 HOH 131 1007 131 HOH HOH A . H 4 HOH 132 1008 132 HOH HOH A . H 4 HOH 133 1009 133 HOH HOH A . H 4 HOH 134 1010 134 HOH HOH A . H 4 HOH 135 1011 135 HOH HOH A . H 4 HOH 136 1012 136 HOH HOH A . H 4 HOH 137 1013 137 HOH HOH A . H 4 HOH 138 1014 138 HOH HOH A . H 4 HOH 139 1015 139 HOH HOH A . H 4 HOH 140 1016 140 HOH HOH A . H 4 HOH 141 1017 141 HOH HOH A . H 4 HOH 142 1018 142 HOH HOH A . H 4 HOH 143 1019 143 HOH HOH A . H 4 HOH 144 1020 144 HOH HOH A . H 4 HOH 145 1021 145 HOH HOH A . H 4 HOH 146 1022 146 HOH HOH A . H 4 HOH 147 1023 147 HOH HOH A . H 4 HOH 148 1024 148 HOH HOH A . H 4 HOH 149 1025 149 HOH HOH A . H 4 HOH 150 1026 150 HOH HOH A . H 4 HOH 151 1027 151 HOH HOH A . H 4 HOH 152 1028 152 HOH HOH A . H 4 HOH 153 1029 153 HOH HOH A . H 4 HOH 154 1030 154 HOH HOH A . H 4 HOH 155 1031 155 HOH HOH A . H 4 HOH 156 1032 156 HOH HOH A . H 4 HOH 157 1033 157 HOH HOH A . H 4 HOH 158 1034 158 HOH HOH A . H 4 HOH 159 1035 159 HOH HOH A . H 4 HOH 160 1036 160 HOH HOH A . H 4 HOH 161 1037 161 HOH HOH A . H 4 HOH 162 1038 162 HOH HOH A . H 4 HOH 163 1039 163 HOH HOH A . H 4 HOH 164 1040 164 HOH HOH A . H 4 HOH 165 1041 165 HOH HOH A . H 4 HOH 166 1042 166 HOH HOH A . H 4 HOH 167 1043 167 HOH HOH A . H 4 HOH 168 1044 168 HOH HOH A . H 4 HOH 169 1045 169 HOH HOH A . H 4 HOH 170 1046 170 HOH HOH A . H 4 HOH 171 1047 171 HOH HOH A . H 4 HOH 172 1048 172 HOH HOH A . H 4 HOH 173 1049 173 HOH HOH A . H 4 HOH 174 1050 174 HOH HOH A . H 4 HOH 175 1051 175 HOH HOH A . H 4 HOH 176 1052 176 HOH HOH A . H 4 HOH 177 1053 177 HOH HOH A . H 4 HOH 178 1054 178 HOH HOH A . H 4 HOH 179 1055 179 HOH HOH A . H 4 HOH 180 1056 180 HOH HOH A . H 4 HOH 181 1057 181 HOH HOH A . H 4 HOH 182 1058 182 HOH HOH A . H 4 HOH 183 1059 183 HOH HOH A . H 4 HOH 184 1060 184 HOH HOH A . H 4 HOH 185 1061 185 HOH HOH A . H 4 HOH 186 1062 186 HOH HOH A . H 4 HOH 187 1063 187 HOH HOH A . H 4 HOH 188 1064 188 HOH HOH A . H 4 HOH 189 1065 189 HOH HOH A . H 4 HOH 190 1066 190 HOH HOH A . H 4 HOH 191 1067 191 HOH HOH A . H 4 HOH 192 1068 192 HOH HOH A . H 4 HOH 193 1069 193 HOH HOH A . H 4 HOH 194 1070 194 HOH HOH A . H 4 HOH 195 1071 195 HOH HOH A . H 4 HOH 196 1072 196 HOH HOH A . H 4 HOH 197 1073 197 HOH HOH A . H 4 HOH 198 1074 198 HOH HOH A . H 4 HOH 199 1075 199 HOH HOH A . H 4 HOH 200 1076 200 HOH HOH A . H 4 HOH 201 1077 201 HOH HOH A . H 4 HOH 202 1078 202 HOH HOH A . H 4 HOH 203 1079 203 HOH HOH A . H 4 HOH 204 1080 204 HOH HOH A . H 4 HOH 205 1081 205 HOH HOH A . H 4 HOH 206 1082 206 HOH HOH A . H 4 HOH 207 1083 207 HOH HOH A . H 4 HOH 208 1084 208 HOH HOH A . H 4 HOH 209 1085 209 HOH HOH A . H 4 HOH 210 1086 210 HOH HOH A . H 4 HOH 211 1087 211 HOH HOH A . H 4 HOH 212 1088 212 HOH HOH A . H 4 HOH 213 1089 213 HOH HOH A . H 4 HOH 214 1090 214 HOH HOH A . H 4 HOH 215 1091 215 HOH HOH A . H 4 HOH 216 1092 216 HOH HOH A . H 4 HOH 217 1093 217 HOH HOH A . H 4 HOH 218 1094 218 HOH HOH A . H 4 HOH 219 1095 219 HOH HOH A . H 4 HOH 220 1096 220 HOH HOH A . H 4 HOH 221 1097 221 HOH HOH A . H 4 HOH 222 1098 222 HOH HOH A . H 4 HOH 223 1099 223 HOH HOH A . H 4 HOH 224 1100 224 HOH HOH A . H 4 HOH 225 1101 225 HOH HOH A . H 4 HOH 226 1102 226 HOH HOH A . H 4 HOH 227 1103 227 HOH HOH A . H 4 HOH 228 1104 228 HOH HOH A . H 4 HOH 229 1105 229 HOH HOH A . H 4 HOH 230 1106 230 HOH HOH A . H 4 HOH 231 1107 231 HOH HOH A . H 4 HOH 232 1108 232 HOH HOH A . H 4 HOH 233 1109 233 HOH HOH A . H 4 HOH 234 1110 234 HOH HOH A . H 4 HOH 235 1111 235 HOH HOH A . H 4 HOH 236 1112 236 HOH HOH A . H 4 HOH 237 1113 237 HOH HOH A . H 4 HOH 238 1114 238 HOH HOH A . H 4 HOH 239 1115 239 HOH HOH A . H 4 HOH 240 1116 240 HOH HOH A . H 4 HOH 241 1117 241 HOH HOH A . H 4 HOH 242 1118 242 HOH HOH A . H 4 HOH 243 1119 243 HOH HOH A . H 4 HOH 244 1120 244 HOH HOH A . H 4 HOH 245 1121 245 HOH HOH A . H 4 HOH 246 1122 246 HOH HOH A . H 4 HOH 247 1123 247 HOH HOH A . H 4 HOH 248 1124 248 HOH HOH A . H 4 HOH 249 1125 249 HOH HOH A . H 4 HOH 250 1126 250 HOH HOH A . H 4 HOH 251 1127 251 HOH HOH A . H 4 HOH 252 1128 252 HOH HOH A . H 4 HOH 253 1129 253 HOH HOH A . H 4 HOH 254 1130 254 HOH HOH A . H 4 HOH 255 1131 255 HOH HOH A . H 4 HOH 256 1132 256 HOH HOH A . H 4 HOH 257 1133 257 HOH HOH A . H 4 HOH 258 1134 258 HOH HOH A . H 4 HOH 259 1135 259 HOH HOH A . H 4 HOH 260 1136 260 HOH HOH A . H 4 HOH 261 1137 261 HOH HOH A . H 4 HOH 262 1138 262 HOH HOH A . H 4 HOH 263 1139 263 HOH HOH A . H 4 HOH 264 1140 264 HOH HOH A . H 4 HOH 265 1141 265 HOH HOH A . H 4 HOH 266 1142 266 HOH HOH A . H 4 HOH 267 1143 267 HOH HOH A . H 4 HOH 268 1144 268 HOH HOH A . H 4 HOH 269 1145 269 HOH HOH A . H 4 HOH 270 1146 270 HOH HOH A . H 4 HOH 271 1147 271 HOH HOH A . H 4 HOH 272 1148 272 HOH HOH A . H 4 HOH 273 1149 273 HOH HOH A . H 4 HOH 274 1150 274 HOH HOH A . H 4 HOH 275 1151 275 HOH HOH A . H 4 HOH 276 1152 276 HOH HOH A . H 4 HOH 277 1153 277 HOH HOH A . H 4 HOH 278 1154 278 HOH HOH A . H 4 HOH 279 1155 279 HOH HOH A . H 4 HOH 280 1156 280 HOH HOH A . H 4 HOH 281 1157 281 HOH HOH A . H 4 HOH 282 1158 282 HOH HOH A . H 4 HOH 283 1159 283 HOH HOH A . H 4 HOH 284 1160 284 HOH HOH A . H 4 HOH 285 1161 285 HOH HOH A . H 4 HOH 286 1162 286 HOH HOH A . H 4 HOH 287 1163 287 HOH HOH A . H 4 HOH 288 1164 288 HOH HOH A . H 4 HOH 289 1165 289 HOH HOH A . H 4 HOH 290 1166 290 HOH HOH A . H 4 HOH 291 1167 291 HOH HOH A . H 4 HOH 292 1168 292 HOH HOH A . H 4 HOH 293 1169 293 HOH HOH A . H 4 HOH 294 1170 294 HOH HOH A . H 4 HOH 295 1171 296 HOH HOH A . H 4 HOH 296 1172 297 HOH HOH A . H 4 HOH 297 1173 298 HOH HOH A . H 4 HOH 298 1174 299 HOH HOH A . H 4 HOH 299 1175 300 HOH HOH A . H 4 HOH 300 1176 301 HOH HOH A . H 4 HOH 301 1177 302 HOH HOH A . H 4 HOH 302 1178 303 HOH HOH A . H 4 HOH 303 1179 304 HOH HOH A . H 4 HOH 304 1180 305 HOH HOH A . H 4 HOH 305 1181 306 HOH HOH A . H 4 HOH 306 1182 307 HOH HOH A . H 4 HOH 307 1183 308 HOH HOH A . H 4 HOH 308 1184 309 HOH HOH A . H 4 HOH 309 1185 310 HOH HOH A . H 4 HOH 310 1186 311 HOH HOH A . H 4 HOH 311 1187 312 HOH HOH A . H 4 HOH 312 1188 313 HOH HOH A . H 4 HOH 313 1189 314 HOH HOH A . H 4 HOH 314 1190 315 HOH HOH A . H 4 HOH 315 1191 316 HOH HOH A . H 4 HOH 316 1192 317 HOH HOH A . H 4 HOH 317 1193 318 HOH HOH A . H 4 HOH 318 1194 319 HOH HOH A . H 4 HOH 319 1195 320 HOH HOH A . H 4 HOH 320 1196 321 HOH HOH A . H 4 HOH 321 1197 322 HOH HOH A . H 4 HOH 322 1198 323 HOH HOH A . H 4 HOH 323 1199 324 HOH HOH A . H 4 HOH 324 1200 325 HOH HOH A . H 4 HOH 325 1201 326 HOH HOH A . H 4 HOH 326 1202 327 HOH HOH A . H 4 HOH 327 1203 328 HOH HOH A . H 4 HOH 328 1204 329 HOH HOH A . H 4 HOH 329 1205 330 HOH HOH A . H 4 HOH 330 1206 331 HOH HOH A . H 4 HOH 331 1207 332 HOH HOH A . H 4 HOH 332 1208 333 HOH HOH A . H 4 HOH 333 1209 334 HOH HOH A . H 4 HOH 334 1210 335 HOH HOH A . H 4 HOH 335 1211 336 HOH HOH A . H 4 HOH 336 1212 338 HOH HOH A . H 4 HOH 337 1213 339 HOH HOH A . H 4 HOH 338 1214 340 HOH HOH A . H 4 HOH 339 1215 341 HOH HOH A . H 4 HOH 340 1216 342 HOH HOH A . H 4 HOH 341 1217 343 HOH HOH A . H 4 HOH 342 1218 344 HOH HOH A . H 4 HOH 343 1219 345 HOH HOH A . H 4 HOH 344 1220 346 HOH HOH A . H 4 HOH 345 1221 347 HOH HOH A . H 4 HOH 346 1222 348 HOH HOH A . H 4 HOH 347 1223 349 HOH HOH A . H 4 HOH 348 1224 350 HOH HOH A . H 4 HOH 349 1225 351 HOH HOH A . H 4 HOH 350 1226 353 HOH HOH A . H 4 HOH 351 1227 354 HOH HOH A . H 4 HOH 352 1228 355 HOH HOH A . H 4 HOH 353 1229 356 HOH HOH A . H 4 HOH 354 1230 357 HOH HOH A . H 4 HOH 355 1231 358 HOH HOH A . H 4 HOH 356 1232 359 HOH HOH A . H 4 HOH 357 1233 360 HOH HOH A . H 4 HOH 358 1234 361 HOH HOH A . H 4 HOH 359 1235 362 HOH HOH A . H 4 HOH 360 1236 364 HOH HOH A . H 4 HOH 361 1237 366 HOH HOH A . H 4 HOH 362 1238 367 HOH HOH A . H 4 HOH 363 1239 368 HOH HOH A . H 4 HOH 364 1240 369 HOH HOH A . H 4 HOH 365 1241 370 HOH HOH A . H 4 HOH 366 1242 371 HOH HOH A . H 4 HOH 367 1243 372 HOH HOH A . H 4 HOH 368 1244 373 HOH HOH A . H 4 HOH 369 1245 374 HOH HOH A . H 4 HOH 370 1246 375 HOH HOH A . H 4 HOH 371 1247 376 HOH HOH A . H 4 HOH 372 1248 377 HOH HOH A . H 4 HOH 373 1249 378 HOH HOH A . H 4 HOH 374 1250 379 HOH HOH A . H 4 HOH 375 1251 380 HOH HOH A . H 4 HOH 376 1252 381 HOH HOH A . H 4 HOH 377 1253 382 HOH HOH A . H 4 HOH 378 1254 383 HOH HOH A . H 4 HOH 379 1255 384 HOH HOH A . H 4 HOH 380 1256 385 HOH HOH A . H 4 HOH 381 1257 386 HOH HOH A . H 4 HOH 382 1258 387 HOH HOH A . H 4 HOH 383 1259 388 HOH HOH A . H 4 HOH 384 1260 389 HOH HOH A . H 4 HOH 385 1261 390 HOH HOH A . H 4 HOH 386 1262 391 HOH HOH A . H 4 HOH 387 1263 392 HOH HOH A . H 4 HOH 388 1264 393 HOH HOH A . H 4 HOH 389 1265 394 HOH HOH A . H 4 HOH 390 1266 395 HOH HOH A . H 4 HOH 391 1267 396 HOH HOH A . H 4 HOH 392 1268 397 HOH HOH A . H 4 HOH 393 1269 398 HOH HOH A . H 4 HOH 394 1270 399 HOH HOH A . H 4 HOH 395 1271 400 HOH HOH A . H 4 HOH 396 1272 401 HOH HOH A . H 4 HOH 397 1273 402 HOH HOH A . H 4 HOH 398 1274 403 HOH HOH A . H 4 HOH 399 1275 404 HOH HOH A . H 4 HOH 400 1276 405 HOH HOH A . H 4 HOH 401 1277 406 HOH HOH A . H 4 HOH 402 1278 407 HOH HOH A . H 4 HOH 403 1279 408 HOH HOH A . H 4 HOH 404 1280 409 HOH HOH A . H 4 HOH 405 1281 410 HOH HOH A . H 4 HOH 406 1282 411 HOH HOH A . H 4 HOH 407 1283 412 HOH HOH A . H 4 HOH 408 1284 413 HOH HOH A . H 4 HOH 409 1285 414 HOH HOH A . H 4 HOH 410 1286 415 HOH HOH A . H 4 HOH 411 1287 416 HOH HOH A . H 4 HOH 412 1288 417 HOH HOH A . H 4 HOH 413 1289 418 HOH HOH A . H 4 HOH 414 1290 419 HOH HOH A . H 4 HOH 415 1291 420 HOH HOH A . H 4 HOH 416 1292 421 HOH HOH A . H 4 HOH 417 1293 422 HOH HOH A . H 4 HOH 418 1294 423 HOH HOH A . H 4 HOH 419 1295 424 HOH HOH A . H 4 HOH 420 1296 425 HOH HOH A . H 4 HOH 421 1297 426 HOH HOH A . H 4 HOH 422 1298 427 HOH HOH A . H 4 HOH 423 1299 428 HOH HOH A . H 4 HOH 424 1300 429 HOH HOH A . H 4 HOH 425 1301 430 HOH HOH A . H 4 HOH 426 1302 431 HOH HOH A . H 4 HOH 427 1303 434 HOH HOH A . H 4 HOH 428 1304 435 HOH HOH A . H 4 HOH 429 1305 436 HOH HOH A . H 4 HOH 430 1306 437 HOH HOH A . H 4 HOH 431 1307 438 HOH HOH A . H 4 HOH 432 1308 439 HOH HOH A . H 4 HOH 433 1309 440 HOH HOH A . H 4 HOH 434 1310 441 HOH HOH A . H 4 HOH 435 1311 442 HOH HOH A . H 4 HOH 436 1312 443 HOH HOH A . H 4 HOH 437 1313 444 HOH HOH A . H 4 HOH 438 1314 445 HOH HOH A . H 4 HOH 439 1315 446 HOH HOH A . H 4 HOH 440 1316 447 HOH HOH A . H 4 HOH 441 1317 448 HOH HOH A . H 4 HOH 442 1318 449 HOH HOH A . H 4 HOH 443 1319 450 HOH HOH A . H 4 HOH 444 1320 451 HOH HOH A . H 4 HOH 445 1321 452 HOH HOH A . H 4 HOH 446 1322 453 HOH HOH A . H 4 HOH 447 1323 454 HOH HOH A . H 4 HOH 448 1324 455 HOH HOH A . H 4 HOH 449 1325 456 HOH HOH A . H 4 HOH 450 1326 457 HOH HOH A . H 4 HOH 451 1327 458 HOH HOH A . H 4 HOH 452 1328 459 HOH HOH A . H 4 HOH 453 1329 460 HOH HOH A . H 4 HOH 454 1330 461 HOH HOH A . H 4 HOH 455 1331 462 HOH HOH A . H 4 HOH 456 1332 463 HOH HOH A . H 4 HOH 457 1333 464 HOH HOH A . H 4 HOH 458 1334 465 HOH HOH A . H 4 HOH 459 1335 466 HOH HOH A . H 4 HOH 460 1336 467 HOH HOH A . H 4 HOH 461 1337 468 HOH HOH A . H 4 HOH 462 1338 469 HOH HOH A . H 4 HOH 463 1339 470 HOH HOH A . H 4 HOH 464 1340 471 HOH HOH A . H 4 HOH 465 1341 472 HOH HOH A . H 4 HOH 466 1342 473 HOH HOH A . H 4 HOH 467 1343 474 HOH HOH A . H 4 HOH 468 1344 475 HOH HOH A . H 4 HOH 469 1345 476 HOH HOH A . H 4 HOH 470 1346 477 HOH HOH A . H 4 HOH 471 1347 478 HOH HOH A . H 4 HOH 472 1348 479 HOH HOH A . H 4 HOH 473 1349 480 HOH HOH A . H 4 HOH 474 1350 481 HOH HOH A . H 4 HOH 475 1351 482 HOH HOH A . H 4 HOH 476 1352 483 HOH HOH A . H 4 HOH 477 1353 484 HOH HOH A . H 4 HOH 478 1354 485 HOH HOH A . H 4 HOH 479 1355 486 HOH HOH A . H 4 HOH 480 1356 487 HOH HOH A . H 4 HOH 481 1357 488 HOH HOH A . H 4 HOH 482 1358 489 HOH HOH A . H 4 HOH 483 1359 490 HOH HOH A . H 4 HOH 484 1360 491 HOH HOH A . H 4 HOH 485 1361 492 HOH HOH A . H 4 HOH 486 1362 493 HOH HOH A . H 4 HOH 487 1363 494 HOH HOH A . H 4 HOH 488 1364 495 HOH HOH A . H 4 HOH 489 1365 496 HOH HOH A . H 4 HOH 490 1366 497 HOH HOH A . H 4 HOH 491 1367 498 HOH HOH A . H 4 HOH 492 1368 499 HOH HOH A . H 4 HOH 493 1369 500 HOH HOH A . H 4 HOH 494 1370 501 HOH HOH A . H 4 HOH 495 1371 502 HOH HOH A . H 4 HOH 496 1372 503 HOH HOH A . H 4 HOH 497 1373 504 HOH HOH A . H 4 HOH 498 1374 505 HOH HOH A . H 4 HOH 499 1375 506 HOH HOH A . H 4 HOH 500 1376 507 HOH HOH A . H 4 HOH 501 1377 508 HOH HOH A . H 4 HOH 502 1378 509 HOH HOH A . H 4 HOH 503 1379 510 HOH HOH A . H 4 HOH 504 1380 511 HOH HOH A . H 4 HOH 505 1381 512 HOH HOH A . H 4 HOH 506 1382 513 HOH HOH A . H 4 HOH 507 1383 514 HOH HOH A . H 4 HOH 508 1384 515 HOH HOH A . H 4 HOH 509 1385 516 HOH HOH A . H 4 HOH 510 1386 517 HOH HOH A . H 4 HOH 511 1387 518 HOH HOH A . H 4 HOH 512 1388 519 HOH HOH A . H 4 HOH 513 1389 520 HOH HOH A . H 4 HOH 514 1390 521 HOH HOH A . H 4 HOH 515 1391 522 HOH HOH A . H 4 HOH 516 1392 523 HOH HOH A . H 4 HOH 517 1393 524 HOH HOH A . H 4 HOH 518 1394 525 HOH HOH A . H 4 HOH 519 1395 526 HOH HOH A . H 4 HOH 520 1396 527 HOH HOH A . H 4 HOH 521 1397 528 HOH HOH A . H 4 HOH 522 1398 529 HOH HOH A . H 4 HOH 523 1399 530 HOH HOH A . H 4 HOH 524 1400 531 HOH HOH A . H 4 HOH 525 1401 532 HOH HOH A . H 4 HOH 526 1402 533 HOH HOH A . H 4 HOH 527 1403 534 HOH HOH A . H 4 HOH 528 1404 535 HOH HOH A . H 4 HOH 529 1405 536 HOH HOH A . H 4 HOH 530 1406 537 HOH HOH A . H 4 HOH 531 1407 538 HOH HOH A . H 4 HOH 532 1408 539 HOH HOH A . H 4 HOH 533 1409 540 HOH HOH A . H 4 HOH 534 1410 541 HOH HOH A . H 4 HOH 535 1411 542 HOH HOH A . H 4 HOH 536 1412 543 HOH HOH A . H 4 HOH 537 1413 544 HOH HOH A . H 4 HOH 538 1414 545 HOH HOH A . H 4 HOH 539 1415 546 HOH HOH A . H 4 HOH 540 1416 547 HOH HOH A . H 4 HOH 541 1417 548 HOH HOH A . H 4 HOH 542 1418 549 HOH HOH A . H 4 HOH 543 1419 550 HOH HOH A . H 4 HOH 544 1420 551 HOH HOH A . H 4 HOH 545 1421 552 HOH HOH A . H 4 HOH 546 1422 553 HOH HOH A . H 4 HOH 547 1423 554 HOH HOH A . H 4 HOH 548 1424 555 HOH HOH A . H 4 HOH 549 1425 556 HOH HOH A . H 4 HOH 550 1426 557 HOH HOH A . H 4 HOH 551 1427 558 HOH HOH A . H 4 HOH 552 1428 559 HOH HOH A . H 4 HOH 553 1429 560 HOH HOH A . H 4 HOH 554 1430 561 HOH HOH A . H 4 HOH 555 1431 562 HOH HOH A . H 4 HOH 556 1432 563 HOH HOH A . H 4 HOH 557 1433 564 HOH HOH A . H 4 HOH 558 1434 565 HOH HOH A . H 4 HOH 559 1435 566 HOH HOH A . H 4 HOH 560 1436 567 HOH HOH A . H 4 HOH 561 1437 568 HOH HOH A . H 4 HOH 562 1438 569 HOH HOH A . H 4 HOH 563 1439 570 HOH HOH A . H 4 HOH 564 1440 571 HOH HOH A . H 4 HOH 565 1441 572 HOH HOH A . H 4 HOH 566 1442 573 HOH HOH A . H 4 HOH 567 1443 574 HOH HOH A . H 4 HOH 568 1444 575 HOH HOH A . H 4 HOH 569 1445 576 HOH HOH A . H 4 HOH 570 1446 577 HOH HOH A . H 4 HOH 571 1447 578 HOH HOH A . H 4 HOH 572 1448 579 HOH HOH A . H 4 HOH 573 1449 580 HOH HOH A . H 4 HOH 574 1450 581 HOH HOH A . H 4 HOH 575 1451 582 HOH HOH A . H 4 HOH 576 1452 583 HOH HOH A . H 4 HOH 577 1453 584 HOH HOH A . H 4 HOH 578 1454 585 HOH HOH A . H 4 HOH 579 1455 586 HOH HOH A . H 4 HOH 580 1456 587 HOH HOH A . H 4 HOH 581 1457 588 HOH HOH A . H 4 HOH 582 1458 589 HOH HOH A . H 4 HOH 583 1459 590 HOH HOH A . H 4 HOH 584 1460 591 HOH HOH A . H 4 HOH 585 1461 592 HOH HOH A . H 4 HOH 586 1462 593 HOH HOH A . H 4 HOH 587 1463 594 HOH HOH A . H 4 HOH 588 1464 595 HOH HOH A . H 4 HOH 589 1465 596 HOH HOH A . H 4 HOH 590 1466 597 HOH HOH A . H 4 HOH 591 1467 598 HOH HOH A . H 4 HOH 592 1468 599 HOH HOH A . H 4 HOH 593 1469 600 HOH HOH A . H 4 HOH 594 1470 601 HOH HOH A . H 4 HOH 595 1471 602 HOH HOH A . H 4 HOH 596 1472 603 HOH HOH A . H 4 HOH 597 1473 604 HOH HOH A . H 4 HOH 598 1474 605 HOH HOH A . H 4 HOH 599 1475 606 HOH HOH A . H 4 HOH 600 1476 607 HOH HOH A . H 4 HOH 601 1477 608 HOH HOH A . H 4 HOH 602 1478 609 HOH HOH A . H 4 HOH 603 1479 610 HOH HOH A . H 4 HOH 604 1480 611 HOH HOH A . H 4 HOH 605 1481 612 HOH HOH A . H 4 HOH 606 1482 613 HOH HOH A . H 4 HOH 607 1483 614 HOH HOH A . H 4 HOH 608 1484 615 HOH HOH A . H 4 HOH 609 1485 616 HOH HOH A . H 4 HOH 610 1486 617 HOH HOH A . H 4 HOH 611 1487 618 HOH HOH A . H 4 HOH 612 1488 619 HOH HOH A . H 4 HOH 613 1489 620 HOH HOH A . H 4 HOH 614 1490 621 HOH HOH A . H 4 HOH 615 1491 622 HOH HOH A . H 4 HOH 616 1492 623 HOH HOH A . H 4 HOH 617 1493 624 HOH HOH A . H 4 HOH 618 1494 625 HOH HOH A . H 4 HOH 619 1495 626 HOH HOH A . H 4 HOH 620 1496 627 HOH HOH A . H 4 HOH 621 1497 628 HOH HOH A . H 4 HOH 622 1498 629 HOH HOH A . H 4 HOH 623 1499 630 HOH HOH A . H 4 HOH 624 1500 631 HOH HOH A . H 4 HOH 625 1501 632 HOH HOH A . H 4 HOH 626 1502 633 HOH HOH A . H 4 HOH 627 1503 634 HOH HOH A . H 4 HOH 628 1504 635 HOH HOH A . H 4 HOH 629 1505 636 HOH HOH A . H 4 HOH 630 1506 637 HOH HOH A . H 4 HOH 631 1507 638 HOH HOH A . H 4 HOH 632 1508 639 HOH HOH A . H 4 HOH 633 1509 640 HOH HOH A . H 4 HOH 634 1510 641 HOH HOH A . H 4 HOH 635 1511 642 HOH HOH A . H 4 HOH 636 1512 643 HOH HOH A . H 4 HOH 637 1513 644 HOH HOH A . H 4 HOH 638 1514 645 HOH HOH A . H 4 HOH 639 1515 646 HOH HOH A . H 4 HOH 640 1516 647 HOH HOH A . H 4 HOH 641 1517 648 HOH HOH A . H 4 HOH 642 1518 649 HOH HOH A . H 4 HOH 643 1519 650 HOH HOH A . H 4 HOH 644 1520 651 HOH HOH A . H 4 HOH 645 1521 652 HOH HOH A . H 4 HOH 646 1522 653 HOH HOH A . H 4 HOH 647 1523 654 HOH HOH A . H 4 HOH 648 1524 655 HOH HOH A . H 4 HOH 649 1525 657 HOH HOH A . H 4 HOH 650 1526 658 HOH HOH A . H 4 HOH 651 1527 659 HOH HOH A . H 4 HOH 652 1528 660 HOH HOH A . H 4 HOH 653 1529 662 HOH HOH A . H 4 HOH 654 1530 663 HOH HOH A . H 4 HOH 655 1531 664 HOH HOH A . H 4 HOH 656 1532 665 HOH HOH A . H 4 HOH 657 1533 666 HOH HOH A . H 4 HOH 658 1534 667 HOH HOH A . H 4 HOH 659 1535 668 HOH HOH A . H 4 HOH 660 1536 669 HOH HOH A . H 4 HOH 661 1537 670 HOH HOH A . H 4 HOH 662 1538 671 HOH HOH A . H 4 HOH 663 1539 672 HOH HOH A . H 4 HOH 664 1540 673 HOH HOH A . H 4 HOH 665 1541 674 HOH HOH A . H 4 HOH 666 1542 675 HOH HOH A . H 4 HOH 667 1543 676 HOH HOH A . H 4 HOH 668 1544 677 HOH HOH A . H 4 HOH 669 1545 678 HOH HOH A . H 4 HOH 670 1546 679 HOH HOH A . H 4 HOH 671 1547 680 HOH HOH A . H 4 HOH 672 1548 681 HOH HOH A . H 4 HOH 673 1549 682 HOH HOH A . H 4 HOH 674 1550 683 HOH HOH A . H 4 HOH 675 1551 684 HOH HOH A . H 4 HOH 676 1552 685 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 393 A ASN 393 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 209 A ASN 209 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 741 A ASN 741 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-09 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-11-01 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 3 'Structure model' '_software.classification' 2 3 'Structure model' '_software.contact_author' 3 3 'Structure model' '_software.contact_author_email' 4 3 'Structure model' '_software.date' 5 3 'Structure model' '_software.language' 6 3 'Structure model' '_software.location' 7 3 'Structure model' '_software.name' 8 3 'Structure model' '_software.type' 9 3 'Structure model' '_software.version' # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 DENZO . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data reduction' http://www.hkl-xray.com/ ? ? 2 SCALEPACK . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data scaling' http://www.hkl-xray.com/ ? ? 3 REFMAC 5.2.0019 ? program 'Garib N. Murshudov' garib@ysbl.york.ac.uk refinement http://www.ccp4.ac.uk/dist/html/refmac5.html Fortran_77 ? 4 PDB_EXTRACT 3.005 'June 11, 2008' package PDB help@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 SG A CYS 479 ? B O A HOH 1151 ? ? 1.97 2 1 OD1 A ASP 191 ? ? O A HOH 1286 ? ? 2.06 3 1 O A GLY 56 ? ? NH1 A ARG 135 ? ? 2.07 4 1 O A HOH 1217 ? ? O A HOH 1232 ? ? 2.19 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 NE _pdbx_validate_rmsd_angle.auth_asym_id_1 A _pdbx_validate_rmsd_angle.auth_comp_id_1 ARG _pdbx_validate_rmsd_angle.auth_seq_id_1 189 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CZ _pdbx_validate_rmsd_angle.auth_asym_id_2 A _pdbx_validate_rmsd_angle.auth_comp_id_2 ARG _pdbx_validate_rmsd_angle.auth_seq_id_2 189 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 NH2 _pdbx_validate_rmsd_angle.auth_asym_id_3 A _pdbx_validate_rmsd_angle.auth_comp_id_3 ARG _pdbx_validate_rmsd_angle.auth_seq_id_3 189 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 116.62 _pdbx_validate_rmsd_angle.angle_target_value 120.30 _pdbx_validate_rmsd_angle.angle_deviation -3.68 _pdbx_validate_rmsd_angle.angle_standard_deviation 0.50 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 34 ? ? -155.72 85.32 2 1 PRO A 35 ? ? -67.70 7.64 3 1 SER A 40 ? ? 79.73 -14.23 4 1 HIS A 50 ? ? 78.24 156.47 5 1 SER A 51 ? ? 128.70 -126.50 6 1 VAL A 77 ? ? -88.87 -77.49 7 1 PHE A 78 ? ? -115.36 76.93 8 1 LEU A 151 ? ? -97.40 -64.22 9 1 PHE A 161 ? ? -150.52 74.41 10 1 PHE A 165 ? ? -162.66 106.62 11 1 LEU A 180 ? ? 68.20 148.98 12 1 GLN A 186 ? ? 79.51 -45.98 13 1 MET A 192 ? ? 81.80 6.53 14 1 MET A 192 ? ? 81.80 6.53 15 1 ASN A 193 ? B -50.76 -163.76 16 1 TRP A 194 ? ? -57.32 108.92 17 1 PHE A 200 ? ? -170.78 115.56 18 1 ASN A 207 ? ? -124.88 -165.25 19 1 LEU A 213 ? ? -115.04 -147.43 20 1 GLU A 300 ? ? 77.05 65.80 21 1 TYR A 321 ? ? -163.90 96.69 22 1 VAL A 342 ? ? -98.97 -66.70 23 1 VAL A 405 ? ? -134.52 -147.41 24 1 ASP A 474 ? ? 76.33 -5.04 25 1 THR A 481 ? ? -152.15 -156.67 26 1 SER A 521 ? ? 53.93 -144.03 27 1 ILE A 565 ? ? -116.72 69.93 28 1 CYS A 573 ? ? 78.65 -9.98 29 1 LEU A 577 ? ? 87.27 158.00 30 1 VAL A 651 ? ? -105.09 -68.01 31 1 PRO A 721 ? ? -59.17 174.73 32 1 GLU A 774 ? ? -150.61 -22.74 33 1 VAL A 783 ? ? -110.44 77.70 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 2002 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 1 ? A SER 1 2 1 Y 1 A ALA 2 ? A ALA 2 3 1 Y 1 A GLU 3 ? A GLU 3 4 1 Y 1 A CYS 4 ? A CYS 4 5 1 Y 1 A PRO 5 ? A PRO 5 6 1 Y 1 A VAL 6 ? A VAL 6 7 1 Y 1 A GLN 837 ? A GLN 837 8 1 Y 1 A HIS 871 ? A HIS 871 9 1 Y 1 A HIS 872 ? A HIS 872 10 1 Y 1 A HIS 873 ? A HIS 873 11 1 Y 1 A HIS 874 ? A HIS 874 12 1 Y 1 A HIS 875 ? A HIS 875 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 ;(1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ; KTL 3 N-ACETYL-D-GLUCOSAMINE NAG 4 water HOH #