data_3K4P # _entry.id 3K4P # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3K4P RCSB RCSB055542 WWPDB D_1000055542 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1ihp 'Aspergillus niger phytase' unspecified PDB 2gfi 'Debaryomyces castellii CBS 2923 phytase' unspecified PDB 1dkl 'Escherichia coli phytase' unspecified PDB 1dkq 'Escherichia coli phytase H17A mutant in complex with myo-inositol hexakisphosphate' unspecified PDB 1qfx 'Aspergillus niger pH 2.5 acid phosphatase' unspecified PDB 3k4q 'Aspergillus niger Phytase in complex with myo-inositol hexakis sulfate' unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3K4P _pdbx_database_status.recvd_initial_deposition_date 2009-10-06 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # _audit_author.name 'Oakley, A.J.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'The structure of Aspergillus niger phytase PhyA in complex with a phytate mimetic' _citation.journal_abbrev Biochem.Biophys.Res.Commun. _citation.journal_volume 397 _citation.page_first 745 _citation.page_last 749 _citation.year 2010 _citation.journal_id_ASTM BBRCA9 _citation.country US _citation.journal_id_ISSN 0006-291X _citation.journal_id_CSD 0146 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20541524 _citation.pdbx_database_id_DOI 10.1016/j.bbrc.2010.06.024 # _citation_author.citation_id primary _citation_author.name 'Oakley, A.J.' _citation_author.ordinal 1 # _cell.entry_id 3K4P _cell.length_a 71.066 _cell.length_b 87.457 _cell.length_c 82.185 _cell.angle_alpha 90.00 _cell.angle_beta 110.98 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3K4P _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man '3-phytase A' 48888.996 2 3.1.3.8 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 3 water nat water 18.015 316 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name '3 phytase A, Myo-inositol-hexaphosphate 3-phosphohydrolase A, Myo-inositol hexakisphosphate phosphohydrolase A' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _entity_poly.pdbx_seq_one_letter_code_can ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ALA n 1 2 SER n 1 3 ARG n 1 4 ASN n 1 5 GLN n 1 6 SER n 1 7 SER n 1 8 CYS n 1 9 ASP n 1 10 THR n 1 11 VAL n 1 12 ASP n 1 13 GLN n 1 14 GLY n 1 15 TYR n 1 16 GLN n 1 17 CYS n 1 18 PHE n 1 19 SER n 1 20 GLU n 1 21 THR n 1 22 SER n 1 23 HIS n 1 24 LEU n 1 25 TRP n 1 26 GLY n 1 27 GLN n 1 28 TYR n 1 29 ALA n 1 30 PRO n 1 31 PHE n 1 32 PHE n 1 33 SER n 1 34 LEU n 1 35 ALA n 1 36 ASN n 1 37 GLU n 1 38 SER n 1 39 VAL n 1 40 ILE n 1 41 SER n 1 42 PRO n 1 43 GLU n 1 44 VAL n 1 45 PRO n 1 46 ALA n 1 47 GLY n 1 48 CYS n 1 49 ARG n 1 50 VAL n 1 51 THR n 1 52 PHE n 1 53 ALA n 1 54 GLN n 1 55 VAL n 1 56 LEU n 1 57 SER n 1 58 ARG n 1 59 HIS n 1 60 GLY n 1 61 ALA n 1 62 ARG n 1 63 TYR n 1 64 PRO n 1 65 THR n 1 66 ASP n 1 67 SER n 1 68 LYS n 1 69 GLY n 1 70 LYS n 1 71 LYS n 1 72 TYR n 1 73 SER n 1 74 ALA n 1 75 LEU n 1 76 ILE n 1 77 GLU n 1 78 GLU n 1 79 ILE n 1 80 GLN n 1 81 GLN n 1 82 ASN n 1 83 ALA n 1 84 THR n 1 85 THR n 1 86 PHE n 1 87 ASP n 1 88 GLY n 1 89 LYS n 1 90 TYR n 1 91 ALA n 1 92 PHE n 1 93 LEU n 1 94 LYS n 1 95 THR n 1 96 TYR n 1 97 ASN n 1 98 TYR n 1 99 SER n 1 100 LEU n 1 101 GLY n 1 102 ALA n 1 103 ASP n 1 104 ASP n 1 105 LEU n 1 106 THR n 1 107 PRO n 1 108 PHE n 1 109 GLY n 1 110 GLU n 1 111 GLN n 1 112 GLU n 1 113 LEU n 1 114 VAL n 1 115 ASN n 1 116 SER n 1 117 GLY n 1 118 ILE n 1 119 LYS n 1 120 PHE n 1 121 TYR n 1 122 GLN n 1 123 ARG n 1 124 TYR n 1 125 GLU n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 ARG n 1 130 ASN n 1 131 ILE n 1 132 VAL n 1 133 PRO n 1 134 PHE n 1 135 ILE n 1 136 ARG n 1 137 SER n 1 138 SER n 1 139 GLY n 1 140 SER n 1 141 SER n 1 142 ARG n 1 143 VAL n 1 144 ILE n 1 145 ALA n 1 146 SER n 1 147 GLY n 1 148 LYS n 1 149 LYS n 1 150 PHE n 1 151 ILE n 1 152 GLU n 1 153 GLY n 1 154 PHE n 1 155 GLN n 1 156 SER n 1 157 THR n 1 158 LYS n 1 159 LEU n 1 160 LYS n 1 161 ASP n 1 162 PRO n 1 163 ARG n 1 164 ALA n 1 165 GLN n 1 166 PRO n 1 167 GLY n 1 168 GLN n 1 169 SER n 1 170 SER n 1 171 PRO n 1 172 LYS n 1 173 ILE n 1 174 ASP n 1 175 VAL n 1 176 VAL n 1 177 ILE n 1 178 SER n 1 179 GLU n 1 180 ALA n 1 181 SER n 1 182 SER n 1 183 SER n 1 184 ASN n 1 185 ASN n 1 186 THR n 1 187 LEU n 1 188 ASP n 1 189 PRO n 1 190 GLY n 1 191 THR n 1 192 CYS n 1 193 THR n 1 194 VAL n 1 195 PHE n 1 196 GLU n 1 197 ASP n 1 198 SER n 1 199 GLU n 1 200 LEU n 1 201 ALA n 1 202 ASP n 1 203 THR n 1 204 VAL n 1 205 GLU n 1 206 ALA n 1 207 ASN n 1 208 PHE n 1 209 THR n 1 210 ALA n 1 211 THR n 1 212 PHE n 1 213 VAL n 1 214 PRO n 1 215 SER n 1 216 ILE n 1 217 ARG n 1 218 GLN n 1 219 ARG n 1 220 LEU n 1 221 GLU n 1 222 ASN n 1 223 ASP n 1 224 LEU n 1 225 SER n 1 226 GLY n 1 227 VAL n 1 228 THR n 1 229 LEU n 1 230 THR n 1 231 ASP n 1 232 THR n 1 233 GLU n 1 234 VAL n 1 235 THR n 1 236 TYR n 1 237 LEU n 1 238 MET n 1 239 ASP n 1 240 MET n 1 241 CYS n 1 242 SER n 1 243 PHE n 1 244 ASP n 1 245 THR n 1 246 ILE n 1 247 SER n 1 248 THR n 1 249 SER n 1 250 THR n 1 251 VAL n 1 252 ASP n 1 253 THR n 1 254 LYS n 1 255 LEU n 1 256 SER n 1 257 PRO n 1 258 PHE n 1 259 CYS n 1 260 ASP n 1 261 LEU n 1 262 PHE n 1 263 THR n 1 264 HIS n 1 265 ASP n 1 266 GLU n 1 267 TRP n 1 268 ILE n 1 269 ASN n 1 270 TYR n 1 271 ASP n 1 272 TYR n 1 273 LEU n 1 274 GLN n 1 275 SER n 1 276 LEU n 1 277 LYS n 1 278 LYS n 1 279 TYR n 1 280 TYR n 1 281 GLY n 1 282 HIS n 1 283 GLY n 1 284 ALA n 1 285 GLY n 1 286 ASN n 1 287 PRO n 1 288 LEU n 1 289 GLY n 1 290 PRO n 1 291 THR n 1 292 GLN n 1 293 GLY n 1 294 VAL n 1 295 GLY n 1 296 TYR n 1 297 ALA n 1 298 ASN n 1 299 GLU n 1 300 LEU n 1 301 ILE n 1 302 ALA n 1 303 ARG n 1 304 LEU n 1 305 THR n 1 306 HIS n 1 307 SER n 1 308 PRO n 1 309 VAL n 1 310 HIS n 1 311 ASP n 1 312 ASP n 1 313 THR n 1 314 SER n 1 315 SER n 1 316 ASN n 1 317 HIS n 1 318 THR n 1 319 LEU n 1 320 ASP n 1 321 SER n 1 322 SER n 1 323 PRO n 1 324 ALA n 1 325 THR n 1 326 PHE n 1 327 PRO n 1 328 LEU n 1 329 ASN n 1 330 SER n 1 331 THR n 1 332 LEU n 1 333 TYR n 1 334 ALA n 1 335 ASP n 1 336 PHE n 1 337 SER n 1 338 HIS n 1 339 ASP n 1 340 ASN n 1 341 GLY n 1 342 ILE n 1 343 ILE n 1 344 SER n 1 345 ILE n 1 346 LEU n 1 347 PHE n 1 348 ALA n 1 349 LEU n 1 350 GLY n 1 351 LEU n 1 352 TYR n 1 353 ASN n 1 354 GLY n 1 355 THR n 1 356 LYS n 1 357 PRO n 1 358 LEU n 1 359 SER n 1 360 THR n 1 361 THR n 1 362 THR n 1 363 VAL n 1 364 GLU n 1 365 ASN n 1 366 ILE n 1 367 THR n 1 368 GLN n 1 369 THR n 1 370 ASP n 1 371 GLY n 1 372 PHE n 1 373 SER n 1 374 SER n 1 375 ALA n 1 376 TRP n 1 377 THR n 1 378 VAL n 1 379 PRO n 1 380 PHE n 1 381 ALA n 1 382 SER n 1 383 ARG n 1 384 LEU n 1 385 TYR n 1 386 VAL n 1 387 GLU n 1 388 MET n 1 389 MET n 1 390 GLN n 1 391 CYS n 1 392 GLN n 1 393 ALA n 1 394 GLU n 1 395 GLN n 1 396 GLU n 1 397 PRO n 1 398 LEU n 1 399 VAL n 1 400 ARG n 1 401 VAL n 1 402 LEU n 1 403 VAL n 1 404 ASN n 1 405 ASP n 1 406 ARG n 1 407 VAL n 1 408 VAL n 1 409 PRO n 1 410 LEU n 1 411 HIS n 1 412 GLY n 1 413 CYS n 1 414 PRO n 1 415 VAL n 1 416 ASP n 1 417 ALA n 1 418 LEU n 1 419 GLY n 1 420 ARG n 1 421 CYS n 1 422 THR n 1 423 ARG n 1 424 ASP n 1 425 SER n 1 426 PHE n 1 427 VAL n 1 428 ARG n 1 429 GLY n 1 430 LEU n 1 431 SER n 1 432 PHE n 1 433 ALA n 1 434 ARG n 1 435 SER n 1 436 GLY n 1 437 GLY n 1 438 ASP n 1 439 TRP n 1 440 ALA n 1 441 GLU n 1 442 CYS n 1 443 PHE n 1 444 ALA n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name ? _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene phyA _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Aspergillus niger' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 5061 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Aspergillus niger' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 5061 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code PHYA_ASPNG _struct_ref.pdbx_db_accession P34752 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _struct_ref.pdbx_align_begin 24 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3K4P A 1 ? 444 ? P34752 24 ? 467 ? 1 444 2 1 3K4P B 1 ? 444 ? P34752 24 ? 467 ? 1 444 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3K4P _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.44 _exptl_crystal.density_percent_sol 49.57 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details '25% (w/v) PEG 3350, 0.4M ammonium nitrate, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2009-08-28 _diffrn_detector.details 'BEAMLINE OPTICS' # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'BEAMLINE OPTICS' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.953715 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'AUSTRALIAN SYNCHROTRON BEAMLINE MX2' _diffrn_source.pdbx_synchrotron_site 'Australian Synchrotron' _diffrn_source.pdbx_synchrotron_beamline MX2 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.953715 # _reflns.entry_id 3K4P _reflns.observed_criterion_sigma_I -3 _reflns.observed_criterion_sigma_F -3 _reflns.d_resolution_low 76.74 _reflns.d_resolution_high 2.4 _reflns.number_obs 35613 _reflns.number_all 35613 _reflns.percent_possible_obs 96.6 _reflns.pdbx_Rmerge_I_obs 0.138 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 6.6 _reflns.B_iso_Wilson_estimate 35.4 _reflns.pdbx_redundancy 3.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 2.4 _reflns_shell.d_res_low 2.53 _reflns_shell.percent_possible_all 99.8 _reflns_shell.Rmerge_I_obs 0.542 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.4 _reflns_shell.pdbx_redundancy 3.5 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 5338 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3K4P _refine.ls_number_reflns_obs 33827 _refine.ls_number_reflns_all 33827 _refine.pdbx_ls_sigma_I -1 _refine.pdbx_ls_sigma_F -1 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 66.36 _refine.ls_d_res_high 2.40 _refine.ls_percent_reflns_obs 96.55 _refine.ls_R_factor_obs 0.21825 _refine.ls_R_factor_all 0.21825 _refine.ls_R_factor_R_work 0.21528 _refine.ls_R_factor_R_free 0.27548 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 1770 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_max 1.00 _refine.occupancy_min 0.50 _refine.correlation_coeff_Fo_to_Fc 0.919 _refine.correlation_coeff_Fo_to_Fc_free 0.873 _refine.B_iso_mean 26.967 _refine.aniso_B[1][1] -0.30 _refine.aniso_B[2][2] 0.08 _refine.aniso_B[3][3] -1.95 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] -3.04 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'PDB ENTRY 1IHP' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.635 _refine.pdbx_overall_ESU_R_Free 0.314 _refine.overall_SU_ML 0.229 _refine.overall_SU_B 9.744 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_max 57.71 _refine.B_iso_min 2.05 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_phase_error ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6777 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 84 _refine_hist.number_atoms_solvent 316 _refine_hist.number_atoms_total 7177 _refine_hist.d_res_high 2.40 _refine_hist.d_res_low 66.36 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.016 0.022 ? 7060 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.680 1.962 ? 9629 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.722 5.000 ? 880 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 38.047 24.224 ? 322 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 16.495 15.000 ? 1078 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 18.610 15.000 ? 37 'X-RAY DIFFRACTION' ? r_chiral_restr 0.111 0.200 ? 1085 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.008 0.021 ? 5455 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.727 1.500 ? 4373 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.330 2.000 ? 7086 'X-RAY DIFFRACTION' ? r_scbond_it 2.023 3.000 ? 2687 'X-RAY DIFFRACTION' ? r_scangle_it 3.247 4.500 ? 2540 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_restr_ncs.dom_id _refine_ls_restr_ncs.pdbx_auth_asym_id _refine_ls_restr_ncs.pdbx_number _refine_ls_restr_ncs.rms_dev_position _refine_ls_restr_ncs.weight_position _refine_ls_restr_ncs.pdbx_type _refine_ls_restr_ncs.pdbx_ens_id _refine_ls_restr_ncs.pdbx_ordinal _refine_ls_restr_ncs.pdbx_refine_id _refine_ls_restr_ncs.ncs_model_details _refine_ls_restr_ncs.rms_dev_B_iso _refine_ls_restr_ncs.weight_B_iso 1 A 3363 0.04 0.05 'tight positional' 1 1 'X-RAY DIFFRACTION' ? ? ? 1 A 3363 0.12 0.50 'tight thermal' 1 2 'X-RAY DIFFRACTION' ? ? ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.400 _refine_ls_shell.d_res_low 2.462 _refine_ls_shell.number_reflns_R_work 2559 _refine_ls_shell.R_factor_R_work 0.249 _refine_ls_shell.percent_reflns_obs 99.70 _refine_ls_shell.R_factor_R_free 0.353 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 124 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs 2559 _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _struct_ncs_dom.id _struct_ncs_dom.details _struct_ncs_dom.pdbx_ens_id 1 A 1 2 B 1 # loop_ _struct_ncs_dom_lim.pdbx_ens_id _struct_ncs_dom_lim.dom_id _struct_ncs_dom_lim.pdbx_component_id _struct_ncs_dom_lim.pdbx_refine_code _struct_ncs_dom_lim.beg_auth_asym_id _struct_ncs_dom_lim.beg_auth_seq_id _struct_ncs_dom_lim.end_auth_asym_id _struct_ncs_dom_lim.end_auth_seq_id _struct_ncs_dom_lim.selection_details _struct_ncs_dom_lim.beg_label_asym_id _struct_ncs_dom_lim.beg_label_comp_id _struct_ncs_dom_lim.beg_label_seq_id _struct_ncs_dom_lim.beg_label_alt_id _struct_ncs_dom_lim.end_label_asym_id _struct_ncs_dom_lim.end_label_comp_id _struct_ncs_dom_lim.end_label_seq_id _struct_ncs_dom_lim.end_label_alt_id 1 1 1 1 A 7 A 444 ? . . . . . . . . 1 2 1 1 B 7 B 444 ? . . . . . . . . # _struct_ncs_ens.id 1 _struct_ncs_ens.details ? # _struct.entry_id 3K4P _struct.title 'Aspergillus niger Phytase' _struct.pdbx_descriptor '3-phytase A (E.C.3.1.3.8)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag N _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3K4P _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text ;Phytase, PhyA, 3-Phosphotase, myo-inositol hexakis phosphate phosphohydrolase, 37288-11-2, Disulfide bond, Glycoprotein, Hydrolase, Secreted ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 3 ? J N N 3 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 PHE A 18 ? HIS A 23 ? PHE A 18 HIS A 23 1 ? 6 HELX_P HELX_P2 2 LEU A 24 ? ALA A 29 ? LEU A 24 ALA A 29 5 ? 6 HELX_P HELX_P3 3 LEU A 34 ? SER A 38 ? LEU A 34 SER A 38 5 ? 5 HELX_P HELX_P4 4 THR A 65 ? ALA A 83 ? THR A 65 ALA A 83 1 ? 19 HELX_P HELX_P5 5 ASP A 87 ? LYS A 94 ? ASP A 87 LYS A 94 5 ? 8 HELX_P HELX_P6 6 THR A 106 ? TYR A 124 ? THR A 106 TYR A 124 1 ? 19 HELX_P HELX_P7 7 TYR A 124 ? ARG A 129 ? TYR A 124 ARG A 129 1 ? 6 HELX_P HELX_P8 8 SER A 140 ? LYS A 160 ? SER A 140 LYS A 160 1 ? 21 HELX_P HELX_P9 9 CYS A 192 ? SER A 198 ? CYS A 192 SER A 198 1 ? 7 HELX_P HELX_P10 10 GLU A 199 ? ALA A 210 ? GLU A 199 ALA A 210 1 ? 12 HELX_P HELX_P11 11 VAL A 213 ? LEU A 224 ? VAL A 213 LEU A 224 1 ? 12 HELX_P HELX_P12 12 THR A 230 ? SER A 247 ? THR A 230 SER A 247 1 ? 18 HELX_P HELX_P13 13 THR A 248 ? THR A 253 ? THR A 248 THR A 253 5 ? 6 HELX_P HELX_P14 14 SER A 256 ? PHE A 262 ? SER A 256 PHE A 262 5 ? 7 HELX_P HELX_P15 15 THR A 263 ? HIS A 282 ? THR A 263 HIS A 282 1 ? 20 HELX_P HELX_P16 16 GLY A 289 ? GLN A 292 ? GLY A 289 GLN A 292 5 ? 4 HELX_P HELX_P17 17 GLY A 293 ? HIS A 306 ? GLY A 293 HIS A 306 1 ? 14 HELX_P HELX_P18 18 ASN A 316 ? SER A 321 ? ASN A 316 SER A 321 1 ? 6 HELX_P HELX_P19 19 HIS A 338 ? LEU A 349 ? HIS A 338 LEU A 349 1 ? 12 HELX_P HELX_P20 20 SER A 373 ? VAL A 378 ? SER A 373 VAL A 378 1 ? 6 HELX_P HELX_P21 21 ARG A 423 ? LEU A 430 ? ARG A 423 LEU A 430 1 ? 8 HELX_P HELX_P22 22 LEU A 430 ? SER A 435 ? LEU A 430 SER A 435 1 ? 6 HELX_P HELX_P23 23 ASP A 438 ? PHE A 443 ? ASP A 438 PHE A 443 5 ? 6 HELX_P HELX_P24 24 PHE B 18 ? HIS B 23 ? PHE B 18 HIS B 23 1 ? 6 HELX_P HELX_P25 25 LEU B 24 ? ALA B 29 ? LEU B 24 ALA B 29 5 ? 6 HELX_P HELX_P26 26 LEU B 34 ? SER B 38 ? LEU B 34 SER B 38 5 ? 5 HELX_P HELX_P27 27 THR B 65 ? ALA B 83 ? THR B 65 ALA B 83 1 ? 19 HELX_P HELX_P28 28 ASP B 87 ? LYS B 94 ? ASP B 87 LYS B 94 5 ? 8 HELX_P HELX_P29 29 THR B 106 ? TYR B 124 ? THR B 106 TYR B 124 1 ? 19 HELX_P HELX_P30 30 TYR B 124 ? ARG B 129 ? TYR B 124 ARG B 129 1 ? 6 HELX_P HELX_P31 31 SER B 140 ? LYS B 160 ? SER B 140 LYS B 160 1 ? 21 HELX_P HELX_P32 32 CYS B 192 ? SER B 198 ? CYS B 192 SER B 198 1 ? 7 HELX_P HELX_P33 33 GLU B 199 ? ALA B 210 ? GLU B 199 ALA B 210 1 ? 12 HELX_P HELX_P34 34 VAL B 213 ? LEU B 224 ? VAL B 213 LEU B 224 1 ? 12 HELX_P HELX_P35 35 THR B 230 ? SER B 247 ? THR B 230 SER B 247 1 ? 18 HELX_P HELX_P36 36 THR B 248 ? THR B 253 ? THR B 248 THR B 253 5 ? 6 HELX_P HELX_P37 37 SER B 256 ? PHE B 262 ? SER B 256 PHE B 262 5 ? 7 HELX_P HELX_P38 38 THR B 263 ? HIS B 282 ? THR B 263 HIS B 282 1 ? 20 HELX_P HELX_P39 39 LEU B 288 ? GLY B 293 ? LEU B 288 GLY B 293 1 ? 6 HELX_P HELX_P40 40 GLY B 293 ? HIS B 306 ? GLY B 293 HIS B 306 1 ? 14 HELX_P HELX_P41 41 ASN B 316 ? SER B 321 ? ASN B 316 SER B 321 1 ? 6 HELX_P HELX_P42 42 HIS B 338 ? LEU B 349 ? HIS B 338 LEU B 349 1 ? 12 HELX_P HELX_P43 43 SER B 373 ? VAL B 378 ? SER B 373 VAL B 378 1 ? 6 HELX_P HELX_P44 44 ARG B 423 ? LEU B 430 ? ARG B 423 LEU B 430 1 ? 8 HELX_P HELX_P45 45 LEU B 430 ? SER B 435 ? LEU B 430 SER B 435 1 ? 6 HELX_P HELX_P46 46 ASP B 438 ? PHE B 443 ? ASP B 438 PHE B 443 5 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 8 SG ? ? ? 1_555 A CYS 17 SG ? ? A CYS 8 A CYS 17 1_555 ? ? ? ? ? ? ? 2.017 ? disulf2 disulf ? ? A CYS 48 SG ? ? ? 1_555 A CYS 391 SG ? ? A CYS 48 A CYS 391 1_555 ? ? ? ? ? ? ? 2.010 ? disulf3 disulf ? ? A CYS 192 SG ? ? ? 1_555 A CYS 442 SG ? ? A CYS 192 A CYS 442 1_555 ? ? ? ? ? ? ? 2.039 ? disulf4 disulf ? ? A CYS 241 SG ? ? ? 1_555 A CYS 259 SG ? ? A CYS 241 A CYS 259 1_555 ? ? ? ? ? ? ? 2.033 ? disulf5 disulf ? ? A CYS 413 SG ? ? ? 1_555 A CYS 421 SG ? ? A CYS 413 A CYS 421 1_555 ? ? ? ? ? ? ? 2.053 ? disulf6 disulf ? ? B CYS 8 SG ? ? ? 1_555 B CYS 17 SG ? ? B CYS 8 B CYS 17 1_555 ? ? ? ? ? ? ? 2.066 ? disulf7 disulf ? ? B CYS 48 SG ? ? ? 1_555 B CYS 391 SG ? ? B CYS 48 B CYS 391 1_555 ? ? ? ? ? ? ? 2.041 ? disulf8 disulf ? ? B CYS 192 SG ? ? ? 1_555 B CYS 442 SG ? ? B CYS 192 B CYS 442 1_555 ? ? ? ? ? ? ? 2.007 ? disulf9 disulf ? ? B CYS 241 SG ? ? ? 1_555 B CYS 259 SG ? ? B CYS 241 B CYS 259 1_555 ? ? ? ? ? ? ? 2.051 ? disulf10 disulf ? ? B CYS 413 SG ? ? ? 1_555 B CYS 421 SG ? ? B CYS 413 B CYS 421 1_555 ? ? ? ? ? ? ? 2.040 ? covale1 covale ? ? A ASN 82 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 82 A NAG 1001 1_555 ? ? ? ? ? ? ? 1.452 ? covale2 covale ? ? A ASN 316 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 316 A NAG 1002 1_555 ? ? ? ? ? ? ? 1.433 ? covale3 covale ? ? A ASN 353 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 353 A NAG 1003 1_555 ? ? ? ? ? ? ? 1.399 ? covale4 covale ? ? B ASN 82 ND2 ? ? ? 1_555 F NAG . C1 ? ? B ASN 82 B NAG 1001 1_555 ? ? ? ? ? ? ? 1.441 ? covale5 covale ? ? B ASN 316 ND2 ? ? ? 1_555 G NAG . C1 ? ? B ASN 316 B NAG 1002 1_555 ? ? ? ? ? ? ? 1.436 ? covale6 covale ? ? B ASN 353 ND2 ? ? ? 1_555 H NAG . C1 ? ? B ASN 353 B NAG 1003 1_555 ? ? ? ? ? ? ? 1.417 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 7 ? C ? 7 ? D ? 2 ? E ? 7 ? F ? 7 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? parallel B 2 3 ? parallel B 3 4 ? parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? parallel C 4 5 ? anti-parallel C 5 6 ? anti-parallel C 6 7 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel E 6 7 ? anti-parallel F 1 2 ? parallel F 2 3 ? parallel F 3 4 ? parallel F 4 5 ? anti-parallel F 5 6 ? anti-parallel F 6 7 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ASP A 9 ? THR A 10 ? ASP A 9 THR A 10 A 2 GLY A 14 ? TYR A 15 ? GLY A 14 TYR A 15 B 1 VAL A 175 ? ILE A 177 ? VAL A 175 ILE A 177 B 2 PHE A 134 ? SER A 138 ? PHE A 134 SER A 138 B 3 LEU A 332 ? SER A 337 ? LEU A 332 SER A 337 B 4 ARG A 49 ? ARG A 58 ? ARG A 49 ARG A 58 B 5 ARG A 383 ? GLN A 390 ? ARG A 383 GLN A 390 B 6 LEU A 398 ? VAL A 403 ? LEU A 398 VAL A 403 B 7 ARG A 406 ? VAL A 407 ? ARG A 406 VAL A 407 C 1 VAL A 175 ? ILE A 177 ? VAL A 175 ILE A 177 C 2 PHE A 134 ? SER A 138 ? PHE A 134 SER A 138 C 3 LEU A 332 ? SER A 337 ? LEU A 332 SER A 337 C 4 ARG A 49 ? ARG A 58 ? ARG A 49 ARG A 58 C 5 ARG A 383 ? GLN A 390 ? ARG A 383 GLN A 390 C 6 LEU A 398 ? VAL A 403 ? LEU A 398 VAL A 403 C 7 CYS A 421 ? THR A 422 ? CYS A 421 THR A 422 D 1 ASP B 9 ? THR B 10 ? ASP B 9 THR B 10 D 2 GLY B 14 ? TYR B 15 ? GLY B 14 TYR B 15 E 1 VAL B 175 ? ILE B 177 ? VAL B 175 ILE B 177 E 2 PHE B 134 ? SER B 138 ? PHE B 134 SER B 138 E 3 LEU B 332 ? SER B 337 ? LEU B 332 SER B 337 E 4 ARG B 49 ? ARG B 58 ? ARG B 49 ARG B 58 E 5 ARG B 383 ? GLN B 390 ? ARG B 383 GLN B 390 E 6 LEU B 398 ? VAL B 403 ? LEU B 398 VAL B 403 E 7 ARG B 406 ? VAL B 407 ? ARG B 406 VAL B 407 F 1 VAL B 175 ? ILE B 177 ? VAL B 175 ILE B 177 F 2 PHE B 134 ? SER B 138 ? PHE B 134 SER B 138 F 3 LEU B 332 ? SER B 337 ? LEU B 332 SER B 337 F 4 ARG B 49 ? ARG B 58 ? ARG B 49 ARG B 58 F 5 ARG B 383 ? GLN B 390 ? ARG B 383 GLN B 390 F 6 LEU B 398 ? VAL B 403 ? LEU B 398 VAL B 403 F 7 CYS B 421 ? THR B 422 ? CYS B 421 THR B 422 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 10 ? N THR A 10 O GLY A 14 ? O GLY A 14 B 1 2 O ILE A 177 ? O ILE A 177 N SER A 137 ? N SER A 137 B 2 3 N ARG A 136 ? N ARG A 136 O ALA A 334 ? O ALA A 334 B 3 4 O ASP A 335 ? O ASP A 335 N SER A 57 ? N SER A 57 B 4 5 N ARG A 49 ? N ARG A 49 O GLN A 390 ? O GLN A 390 B 5 6 N GLU A 387 ? N GLU A 387 O ARG A 400 ? O ARG A 400 B 6 7 N VAL A 403 ? N VAL A 403 O ARG A 406 ? O ARG A 406 C 1 2 O ILE A 177 ? O ILE A 177 N SER A 137 ? N SER A 137 C 2 3 N ARG A 136 ? N ARG A 136 O ALA A 334 ? O ALA A 334 C 3 4 O ASP A 335 ? O ASP A 335 N SER A 57 ? N SER A 57 C 4 5 N ARG A 49 ? N ARG A 49 O GLN A 390 ? O GLN A 390 C 5 6 N GLU A 387 ? N GLU A 387 O ARG A 400 ? O ARG A 400 C 6 7 N VAL A 399 ? N VAL A 399 O CYS A 421 ? O CYS A 421 D 1 2 N THR B 10 ? N THR B 10 O GLY B 14 ? O GLY B 14 E 1 2 O ILE B 177 ? O ILE B 177 N SER B 137 ? N SER B 137 E 2 3 N ARG B 136 ? N ARG B 136 O ALA B 334 ? O ALA B 334 E 3 4 O ASP B 335 ? O ASP B 335 N SER B 57 ? N SER B 57 E 4 5 N ARG B 49 ? N ARG B 49 O GLN B 390 ? O GLN B 390 E 5 6 N GLU B 387 ? N GLU B 387 O ARG B 400 ? O ARG B 400 E 6 7 N VAL B 403 ? N VAL B 403 O ARG B 406 ? O ARG B 406 F 1 2 O ILE B 177 ? O ILE B 177 N SER B 137 ? N SER B 137 F 2 3 N ARG B 136 ? N ARG B 136 O ALA B 334 ? O ALA B 334 F 3 4 O ASP B 335 ? O ASP B 335 N SER B 57 ? N SER B 57 F 4 5 N ARG B 49 ? N ARG B 49 O GLN B 390 ? O GLN B 390 F 5 6 N GLU B 387 ? N GLU B 387 O ARG B 400 ? O ARG B 400 F 6 7 N VAL B 399 ? N VAL B 399 O CYS B 421 ? O CYS B 421 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 1001' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 1002' AC3 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 1003' AC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 1001' AC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 1002' AC6 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE NAG B 1003' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 GLU A 78 ? GLU A 78 . ? 1_555 ? 2 AC1 5 ASN A 82 ? ASN A 82 . ? 1_555 ? 3 AC1 5 VAL A 227 ? VAL A 227 . ? 1_555 ? 4 AC1 5 THR A 228 ? THR A 228 . ? 1_555 ? 5 AC1 5 HOH I . ? HOH A 471 . ? 1_555 ? 6 AC2 5 SER A 182 ? SER A 182 . ? 1_555 ? 7 AC2 5 SER A 183 ? SER A 183 . ? 1_555 ? 8 AC2 5 ASN A 184 ? ASN A 184 . ? 1_555 ? 9 AC2 5 ASN A 316 ? ASN A 316 . ? 1_555 ? 10 AC2 5 HOH I . ? HOH A 466 . ? 1_555 ? 11 AC3 10 ASN A 353 ? ASN A 353 . ? 1_555 ? 12 AC3 10 GLY A 412 ? GLY A 412 . ? 1_555 ? 13 AC3 10 GLY A 429 ? GLY A 429 . ? 1_555 ? 14 AC3 10 PHE A 432 ? PHE A 432 . ? 1_555 ? 15 AC3 10 HOH I . ? HOH A 593 . ? 1_555 ? 16 AC3 10 HOH I . ? HOH A 598 . ? 1_555 ? 17 AC3 10 ASN B 130 ? ASN B 130 . ? 1_556 ? 18 AC3 10 ARG B 163 ? ARG B 163 . ? 1_556 ? 19 AC3 10 ALA B 164 ? ALA B 164 . ? 1_556 ? 20 AC3 10 GLN B 165 ? GLN B 165 . ? 1_556 ? 21 AC4 5 GLU B 78 ? GLU B 78 . ? 1_555 ? 22 AC4 5 ASN B 82 ? ASN B 82 . ? 1_555 ? 23 AC4 5 VAL B 227 ? VAL B 227 . ? 1_555 ? 24 AC4 5 THR B 228 ? THR B 228 . ? 1_555 ? 25 AC4 5 HOH J . ? HOH B 484 . ? 1_555 ? 26 AC5 4 SER B 183 ? SER B 183 . ? 1_555 ? 27 AC5 4 ASN B 184 ? ASN B 184 . ? 1_555 ? 28 AC5 4 ASN B 316 ? ASN B 316 . ? 1_555 ? 29 AC5 4 HOH J . ? HOH B 471 . ? 1_555 ? 30 AC6 11 ASN A 130 ? ASN A 130 . ? 1_655 ? 31 AC6 11 ARG A 163 ? ARG A 163 . ? 1_655 ? 32 AC6 11 ALA A 164 ? ALA A 164 . ? 1_655 ? 33 AC6 11 GLN A 165 ? GLN A 165 . ? 1_655 ? 34 AC6 11 ASN B 353 ? ASN B 353 . ? 1_555 ? 35 AC6 11 HIS B 411 ? HIS B 411 . ? 1_555 ? 36 AC6 11 GLY B 412 ? GLY B 412 . ? 1_555 ? 37 AC6 11 GLY B 429 ? GLY B 429 . ? 1_555 ? 38 AC6 11 PHE B 432 ? PHE B 432 . ? 1_555 ? 39 AC6 11 HOH J . ? HOH B 451 . ? 1_555 ? 40 AC6 11 HOH J . ? HOH B 549 . ? 1_555 ? # _database_PDB_matrix.entry_id 3K4P _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3K4P _atom_sites.fract_transf_matrix[1][1] 0.014071 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.005396 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.011434 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.013032 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 7 ? 2.533 0.280 9.265 1.00 43.08 ? 7 SER A N 1 ATOM 2 C CA . SER A 1 7 ? 2.501 -1.178 8.864 1.00 43.27 ? 7 SER A CA 1 ATOM 3 C C . SER A 1 7 ? 2.993 -2.154 9.957 1.00 42.87 ? 7 SER A C 1 ATOM 4 O O . SER A 1 7 ? 2.853 -3.371 9.806 1.00 43.30 ? 7 SER A O 1 ATOM 5 C CB . SER A 1 7 ? 3.259 -1.410 7.557 1.00 43.80 ? 7 SER A CB 1 ATOM 6 O OG . SER A 1 7 ? 2.730 -0.600 6.504 1.00 45.66 ? 7 SER A OG 1 ATOM 7 N N . CYS A 1 8 ? 3.595 -1.616 11.025 1.00 41.72 ? 8 CYS A N 1 ATOM 8 C CA . CYS A 1 8 ? 3.784 -2.334 12.306 1.00 40.51 ? 8 CYS A CA 1 ATOM 9 C C . CYS A 1 8 ? 2.697 -1.810 13.257 1.00 39.30 ? 8 CYS A C 1 ATOM 10 O O . CYS A 1 8 ? 2.558 -2.271 14.386 1.00 39.20 ? 8 CYS A O 1 ATOM 11 C CB . CYS A 1 8 ? 5.208 -2.139 12.903 1.00 39.99 ? 8 CYS A CB 1 ATOM 12 S SG . CYS A 1 8 ? 5.916 -0.402 12.896 1.00 40.75 ? 8 CYS A SG 1 ATOM 13 N N . ASP A 1 9 ? 1.947 -0.830 12.772 1.00 37.46 ? 9 ASP A N 1 ATOM 14 C CA . ASP A 1 9 ? 0.786 -0.308 13.447 1.00 36.75 ? 9 ASP A CA 1 ATOM 15 C C . ASP A 1 9 ? -0.466 -0.597 12.591 1.00 36.23 ? 9 ASP A C 1 ATOM 16 O O . ASP A 1 9 ? -0.729 0.121 11.612 1.00 36.98 ? 9 ASP A O 1 ATOM 17 C CB . ASP A 1 9 ? 0.955 1.201 13.623 1.00 36.78 ? 9 ASP A CB 1 ATOM 18 C CG . ASP A 1 9 ? -0.105 1.824 14.525 1.00 36.67 ? 9 ASP A CG 1 ATOM 19 O OD1 . ASP A 1 9 ? -0.697 1.113 15.376 1.00 37.88 ? 9 ASP A OD1 1 ATOM 20 O OD2 . ASP A 1 9 ? -0.315 3.044 14.404 1.00 37.08 ? 9 ASP A OD2 1 ATOM 21 N N . THR A 1 10 ? -1.224 -1.625 12.958 1.00 34.11 ? 10 THR A N 1 ATOM 22 C CA . THR A 1 10 ? -2.386 -2.037 12.194 1.00 33.14 ? 10 THR A CA 1 ATOM 23 C C . THR A 1 10 ? -3.684 -1.905 12.993 1.00 32.78 ? 10 THR A C 1 ATOM 24 O O . THR A 1 10 ? -3.677 -1.714 14.214 1.00 32.18 ? 10 THR A O 1 ATOM 25 C CB . THR A 1 10 ? -2.275 -3.504 11.790 1.00 32.96 ? 10 THR A CB 1 ATOM 26 O OG1 . THR A 1 10 ? -2.052 -4.292 12.959 1.00 32.96 ? 10 THR A OG1 1 ATOM 27 C CG2 . THR A 1 10 ? -1.132 -3.731 10.813 1.00 32.50 ? 10 THR A CG2 1 ATOM 28 N N . VAL A 1 11 ? -4.808 -2.058 12.312 1.00 32.29 ? 11 VAL A N 1 ATOM 29 C CA . VAL A 1 11 ? -6.090 -2.053 13.017 1.00 32.20 ? 11 VAL A CA 1 ATOM 30 C C . VAL A 1 11 ? -6.190 -3.278 13.897 1.00 31.90 ? 11 VAL A C 1 ATOM 31 O O . VAL A 1 11 ? -6.651 -3.194 15.033 1.00 31.45 ? 11 VAL A O 1 ATOM 32 C CB . VAL A 1 11 ? -7.290 -1.984 12.053 1.00 32.30 ? 11 VAL A CB 1 ATOM 33 C CG1 . VAL A 1 11 ? -8.619 -2.318 12.774 1.00 31.49 ? 11 VAL A CG1 1 ATOM 34 C CG2 . VAL A 1 11 ? -7.338 -0.596 11.374 1.00 32.42 ? 11 VAL A CG2 1 ATOM 35 N N . ASP A 1 12 ? -5.728 -4.414 13.388 1.00 32.10 ? 12 ASP A N 1 ATOM 36 C CA . ASP A 1 12 ? -5.986 -5.655 14.091 1.00 32.13 ? 12 ASP A CA 1 ATOM 37 C C . ASP A 1 12 ? -5.048 -5.929 15.256 1.00 31.26 ? 12 ASP A C 1 ATOM 38 O O . ASP A 1 12 ? -5.483 -6.420 16.310 1.00 30.76 ? 12 ASP A O 1 ATOM 39 C CB . ASP A 1 12 ? -5.965 -6.830 13.132 1.00 32.94 ? 12 ASP A CB 1 ATOM 40 C CG . ASP A 1 12 ? -7.203 -7.699 13.278 1.00 36.48 ? 12 ASP A CG 1 ATOM 41 O OD1 . ASP A 1 12 ? -7.210 -8.615 14.180 1.00 32.56 ? 12 ASP A OD1 1 ATOM 42 O OD2 . ASP A 1 12 ? -8.157 -7.427 12.468 1.00 39.91 ? 12 ASP A OD2 1 ATOM 43 N N . GLN A 1 13 ? -3.774 -5.610 15.066 1.00 30.09 ? 13 GLN A N 1 ATOM 44 C CA . GLN A 1 13 ? -2.752 -6.017 16.018 1.00 29.65 ? 13 GLN A CA 1 ATOM 45 C C . GLN A 1 13 ? -2.279 -4.876 16.905 1.00 28.96 ? 13 GLN A C 1 ATOM 46 O O . GLN A 1 13 ? -1.582 -5.124 17.892 1.00 28.89 ? 13 GLN A O 1 ATOM 47 C CB . GLN A 1 13 ? -1.588 -6.711 15.306 1.00 29.69 ? 13 GLN A CB 1 ATOM 48 C CG . GLN A 1 13 ? -1.905 -8.156 14.907 1.00 31.85 ? 13 GLN A CG 1 ATOM 49 C CD . GLN A 1 13 ? -2.043 -9.089 16.114 1.00 35.89 ? 13 GLN A CD 1 ATOM 50 O OE1 . GLN A 1 13 ? -1.044 -9.403 16.772 1.00 38.04 ? 13 GLN A OE1 1 ATOM 51 N NE2 . GLN A 1 13 ? -3.283 -9.551 16.401 1.00 35.51 ? 13 GLN A NE2 1 ATOM 52 N N . GLY A 1 14 ? -2.678 -3.644 16.567 1.00 28.39 ? 14 GLY A N 1 ATOM 53 C CA . GLY A 1 14 ? -2.474 -2.473 17.427 1.00 28.07 ? 14 GLY A CA 1 ATOM 54 C C . GLY A 1 14 ? -1.100 -1.918 17.119 1.00 28.50 ? 14 GLY A C 1 ATOM 55 O O . GLY A 1 14 ? -0.670 -1.985 15.971 1.00 28.72 ? 14 GLY A O 1 ATOM 56 N N . TYR A 1 15 ? -0.397 -1.402 18.128 1.00 27.88 ? 15 TYR A N 1 ATOM 57 C CA . TYR A 1 15 ? 0.885 -0.767 17.888 1.00 28.65 ? 15 TYR A CA 1 ATOM 58 C C . TYR A 1 15 ? 2.081 -1.676 18.159 1.00 29.15 ? 15 TYR A C 1 ATOM 59 O O . TYR A 1 15 ? 2.551 -1.756 19.299 1.00 29.51 ? 15 TYR A O 1 ATOM 60 C CB . TYR A 1 15 ? 0.972 0.474 18.720 1.00 27.83 ? 15 TYR A CB 1 ATOM 61 C CG . TYR A 1 15 ? 2.215 1.300 18.501 1.00 29.19 ? 15 TYR A CG 1 ATOM 62 C CD1 . TYR A 1 15 ? 2.251 2.320 17.527 1.00 29.20 ? 15 TYR A CD1 1 ATOM 63 C CD2 . TYR A 1 15 ? 3.353 1.099 19.287 1.00 27.91 ? 15 TYR A CD2 1 ATOM 64 C CE1 . TYR A 1 15 ? 3.391 3.114 17.361 1.00 28.20 ? 15 TYR A CE1 1 ATOM 65 C CE2 . TYR A 1 15 ? 4.478 1.871 19.117 1.00 27.69 ? 15 TYR A CE2 1 ATOM 66 C CZ . TYR A 1 15 ? 4.500 2.875 18.167 1.00 28.10 ? 15 TYR A CZ 1 ATOM 67 O OH . TYR A 1 15 ? 5.653 3.609 18.052 1.00 27.00 ? 15 TYR A OH 1 ATOM 68 N N . GLN A 1 16 ? 2.569 -2.350 17.114 1.00 29.85 ? 16 GLN A N 1 ATOM 69 C CA . GLN A 1 16 ? 3.675 -3.337 17.243 1.00 30.82 ? 16 GLN A CA 1 ATOM 70 C C . GLN A 1 16 ? 5.050 -2.795 16.805 1.00 31.94 ? 16 GLN A C 1 ATOM 71 O O . GLN A 1 16 ? 6.020 -3.535 16.722 1.00 33.32 ? 16 GLN A O 1 ATOM 72 C CB . GLN A 1 16 ? 3.358 -4.667 16.512 1.00 29.89 ? 16 GLN A CB 1 ATOM 73 C CG . GLN A 1 16 ? 2.033 -5.287 16.856 1.00 29.29 ? 16 GLN A CG 1 ATOM 74 C CD . GLN A 1 16 ? 1.990 -5.989 18.225 1.00 31.44 ? 16 GLN A CD 1 ATOM 75 O OE1 . GLN A 1 16 ? 3.021 -6.242 18.851 1.00 28.59 ? 16 GLN A OE1 1 ATOM 76 N NE2 . GLN A 1 16 ? 0.777 -6.330 18.679 1.00 30.34 ? 16 GLN A NE2 1 ATOM 77 N N . CYS A 1 17 ? 5.137 -1.505 16.518 1.00 33.08 ? 17 CYS A N 1 ATOM 78 C CA . CYS A 1 17 ? 6.416 -0.870 16.272 1.00 33.66 ? 17 CYS A CA 1 ATOM 79 C C . CYS A 1 17 ? 7.197 -0.784 17.591 1.00 33.82 ? 17 CYS A C 1 ATOM 80 O O . CYS A 1 17 ? 6.603 -0.512 18.657 1.00 34.12 ? 17 CYS A O 1 ATOM 81 C CB . CYS A 1 17 ? 6.180 0.533 15.722 1.00 34.08 ? 17 CYS A CB 1 ATOM 82 S SG . CYS A 1 17 ? 4.975 0.623 14.356 1.00 36.46 ? 17 CYS A SG 1 ATOM 83 N N . PHE A 1 18 ? 8.515 -1.031 17.519 1.00 33.00 ? 18 PHE A N 1 ATOM 84 C CA . PHE A 1 18 ? 9.445 -0.796 18.634 1.00 32.30 ? 18 PHE A CA 1 ATOM 85 C C . PHE A 1 18 ? 9.037 -1.500 19.935 1.00 32.08 ? 18 PHE A C 1 ATOM 86 O O . PHE A 1 18 ? 9.234 -0.964 21.045 1.00 32.24 ? 18 PHE A O 1 ATOM 87 C CB . PHE A 1 18 ? 9.576 0.701 18.906 1.00 31.84 ? 18 PHE A CB 1 ATOM 88 C CG . PHE A 1 18 ? 9.788 1.511 17.681 1.00 32.06 ? 18 PHE A CG 1 ATOM 89 C CD1 . PHE A 1 18 ? 10.884 1.255 16.844 1.00 31.69 ? 18 PHE A CD1 1 ATOM 90 C CD2 . PHE A 1 18 ? 8.890 2.530 17.336 1.00 30.81 ? 18 PHE A CD2 1 ATOM 91 C CE1 . PHE A 1 18 ? 11.074 2.018 15.674 1.00 30.73 ? 18 PHE A CE1 1 ATOM 92 C CE2 . PHE A 1 18 ? 9.086 3.294 16.187 1.00 29.68 ? 18 PHE A CE2 1 ATOM 93 C CZ . PHE A 1 18 ? 10.179 3.048 15.366 1.00 29.13 ? 18 PHE A CZ 1 ATOM 94 N N . SER A 1 19 ? 8.493 -2.700 19.781 1.00 31.82 ? 19 SER A N 1 ATOM 95 C CA . SER A 1 19 ? 7.733 -3.371 20.832 1.00 31.74 ? 19 SER A CA 1 ATOM 96 C C . SER A 1 19 ? 8.545 -3.627 22.105 1.00 30.65 ? 19 SER A C 1 ATOM 97 O O . SER A 1 19 ? 7.972 -3.692 23.189 1.00 30.43 ? 19 SER A O 1 ATOM 98 C CB . SER A 1 19 ? 7.167 -4.683 20.294 1.00 31.94 ? 19 SER A CB 1 ATOM 99 O OG . SER A 1 19 ? 8.241 -5.587 20.057 1.00 34.15 ? 19 SER A OG 1 ATOM 100 N N . GLU A 1 20 ? 9.867 -3.745 21.960 1.00 29.68 ? 20 GLU A N 1 ATOM 101 C CA . GLU A 1 20 ? 10.773 -4.057 23.082 1.00 29.24 ? 20 GLU A CA 1 ATOM 102 C C . GLU A 1 20 ? 10.909 -2.888 24.052 1.00 27.69 ? 20 GLU A C 1 ATOM 103 O O . GLU A 1 20 ? 11.310 -3.081 25.179 1.00 27.48 ? 20 GLU A O 1 ATOM 104 C CB . GLU A 1 20 ? 12.165 -4.578 22.601 1.00 29.98 ? 20 GLU A CB 1 ATOM 105 C CG . GLU A 1 20 ? 13.098 -3.530 21.933 1.00 32.52 ? 20 GLU A CG 1 ATOM 106 C CD . GLU A 1 20 ? 12.545 -2.951 20.590 1.00 39.20 ? 20 GLU A CD 1 ATOM 107 O OE1 . GLU A 1 20 ? 11.941 -3.725 19.787 1.00 37.48 ? 20 GLU A OE1 1 ATOM 108 O OE2 . GLU A 1 20 ? 12.714 -1.712 20.344 1.00 41.81 ? 20 GLU A OE2 1 ATOM 109 N N . THR A 1 21 ? 10.554 -1.692 23.590 1.00 26.30 ? 21 THR A N 1 ATOM 110 C CA . THR A 1 21 ? 10.461 -0.491 24.393 1.00 25.19 ? 21 THR A CA 1 ATOM 111 C C . THR A 1 21 ? 8.988 -0.049 24.594 1.00 25.59 ? 21 THR A C 1 ATOM 112 O O . THR A 1 21 ? 8.529 0.122 25.732 1.00 24.89 ? 21 THR A O 1 ATOM 113 C CB . THR A 1 21 ? 11.236 0.620 23.704 1.00 24.43 ? 21 THR A CB 1 ATOM 114 O OG1 . THR A 1 21 ? 12.605 0.258 23.700 1.00 26.35 ? 21 THR A OG1 1 ATOM 115 C CG2 . THR A 1 21 ? 11.087 1.938 24.420 1.00 23.20 ? 21 THR A CG2 1 ATOM 116 N N . SER A 1 22 ? 8.259 0.128 23.488 1.00 25.47 ? 22 SER A N 1 ATOM 117 C CA . SER A 1 22 ? 6.918 0.753 23.515 1.00 26.07 ? 22 SER A CA 1 ATOM 118 C C . SER A 1 22 ? 5.883 -0.006 24.351 1.00 26.58 ? 22 SER A C 1 ATOM 119 O O . SER A 1 22 ? 4.906 0.592 24.818 1.00 27.77 ? 22 SER A O 1 ATOM 120 C CB . SER A 1 22 ? 6.385 0.947 22.093 1.00 25.72 ? 22 SER A CB 1 ATOM 121 O OG . SER A 1 22 ? 6.293 -0.297 21.398 1.00 25.48 ? 22 SER A OG 1 ATOM 122 N N . HIS A 1 23 ? 6.089 -1.312 24.521 1.00 25.91 ? 23 HIS A N 1 ATOM 123 C CA . HIS A 1 23 ? 5.190 -2.181 25.281 1.00 25.31 ? 23 HIS A CA 1 ATOM 124 C C . HIS A 1 23 ? 5.419 -2.105 26.804 1.00 24.98 ? 23 HIS A C 1 ATOM 125 O O . HIS A 1 23 ? 4.589 -2.585 27.592 1.00 24.33 ? 23 HIS A O 1 ATOM 126 C CB . HIS A 1 23 ? 5.293 -3.626 24.765 1.00 24.86 ? 23 HIS A CB 1 ATOM 127 C CG . HIS A 1 23 ? 4.673 -3.829 23.412 1.00 28.03 ? 23 HIS A CG 1 ATOM 128 N ND1 . HIS A 1 23 ? 4.414 -5.083 22.883 1.00 31.83 ? 23 HIS A ND1 1 ATOM 129 C CD2 . HIS A 1 23 ? 4.236 -2.936 22.486 1.00 28.22 ? 23 HIS A CD2 1 ATOM 130 C CE1 . HIS A 1 23 ? 3.842 -4.948 21.693 1.00 29.78 ? 23 HIS A CE1 1 ATOM 131 N NE2 . HIS A 1 23 ? 3.718 -3.657 21.433 1.00 27.38 ? 23 HIS A NE2 1 ATOM 132 N N . LEU A 1 24 ? 6.521 -1.477 27.216 1.00 24.65 ? 24 LEU A N 1 ATOM 133 C CA . LEU A 1 24 ? 6.846 -1.386 28.642 1.00 24.47 ? 24 LEU A CA 1 ATOM 134 C C . LEU A 1 24 ? 6.599 0.016 29.181 1.00 23.52 ? 24 LEU A C 1 ATOM 135 O O . LEU A 1 24 ? 7.241 0.415 30.158 1.00 23.19 ? 24 LEU A O 1 ATOM 136 C CB . LEU A 1 24 ? 8.289 -1.873 28.944 1.00 24.61 ? 24 LEU A CB 1 ATOM 137 C CG . LEU A 1 24 ? 8.637 -3.313 28.513 1.00 25.25 ? 24 LEU A CG 1 ATOM 138 C CD1 . LEU A 1 24 ? 10.141 -3.526 28.380 1.00 26.55 ? 24 LEU A CD1 1 ATOM 139 C CD2 . LEU A 1 24 ? 8.042 -4.377 29.400 1.00 23.75 ? 24 LEU A CD2 1 ATOM 140 N N . TRP A 1 25 ? 5.668 0.757 28.557 1.00 22.02 ? 25 TRP A N 1 ATOM 141 C CA . TRP A 1 25 ? 5.307 2.087 29.076 1.00 21.18 ? 25 TRP A CA 1 ATOM 142 C C . TRP A 1 25 ? 4.052 2.005 29.974 1.00 19.75 ? 25 TRP A C 1 ATOM 143 O O . TRP A 1 25 ? 3.422 3.005 30.306 1.00 18.53 ? 25 TRP A O 1 ATOM 144 C CB . TRP A 1 25 ? 5.110 3.089 27.941 1.00 21.16 ? 25 TRP A CB 1 ATOM 145 C CG . TRP A 1 25 ? 6.343 3.311 27.079 1.00 23.47 ? 25 TRP A CG 1 ATOM 146 C CD1 . TRP A 1 25 ? 7.639 3.227 27.471 1.00 23.59 ? 25 TRP A CD1 1 ATOM 147 C CD2 . TRP A 1 25 ? 6.371 3.691 25.693 1.00 24.41 ? 25 TRP A CD2 1 ATOM 148 N NE1 . TRP A 1 25 ? 8.478 3.516 26.427 1.00 23.33 ? 25 TRP A NE1 1 ATOM 149 C CE2 . TRP A 1 25 ? 7.728 3.813 25.323 1.00 25.05 ? 25 TRP A CE2 1 ATOM 150 C CE3 . TRP A 1 25 ? 5.382 3.941 24.732 1.00 23.72 ? 25 TRP A CE3 1 ATOM 151 C CZ2 . TRP A 1 25 ? 8.130 4.158 24.011 1.00 25.03 ? 25 TRP A CZ2 1 ATOM 152 C CZ3 . TRP A 1 25 ? 5.781 4.297 23.429 1.00 25.10 ? 25 TRP A CZ3 1 ATOM 153 C CH2 . TRP A 1 25 ? 7.141 4.410 23.090 1.00 24.59 ? 25 TRP A CH2 1 ATOM 154 N N . GLY A 1 26 ? 3.688 0.803 30.361 1.00 19.06 ? 26 GLY A N 1 ATOM 155 C CA . GLY A 1 26 ? 2.445 0.626 31.162 1.00 19.71 ? 26 GLY A CA 1 ATOM 156 C C . GLY A 1 26 ? 1.209 1.243 30.535 1.00 19.20 ? 26 GLY A C 1 ATOM 157 O O . GLY A 1 26 ? 0.875 0.933 29.395 1.00 19.90 ? 26 GLY A O 1 ATOM 158 N N . GLN A 1 27 ? 0.556 2.131 31.279 1.00 18.65 ? 27 GLN A N 1 ATOM 159 C CA . GLN A 1 27 ? -0.676 2.743 30.865 1.00 18.17 ? 27 GLN A CA 1 ATOM 160 C C . GLN A 1 27 ? -0.380 3.901 29.949 1.00 18.65 ? 27 GLN A C 1 ATOM 161 O O . GLN A 1 27 ? -1.317 4.591 29.457 1.00 18.72 ? 27 GLN A O 1 ATOM 162 C CB . GLN A 1 27 ? -1.534 3.201 32.065 1.00 18.27 ? 27 GLN A CB 1 ATOM 163 C CG . GLN A 1 27 ? -1.032 4.460 32.859 1.00 18.32 ? 27 GLN A CG 1 ATOM 164 C CD . GLN A 1 27 ? 0.225 4.200 33.678 1.00 21.50 ? 27 GLN A CD 1 ATOM 165 O OE1 . GLN A 1 27 ? 0.361 3.146 34.317 1.00 22.63 ? 27 GLN A OE1 1 ATOM 166 N NE2 . GLN A 1 27 ? 1.159 5.173 33.670 1.00 21.36 ? 27 GLN A NE2 1 ATOM 167 N N . TYR A 1 28 ? 0.911 4.116 29.713 1.00 18.53 ? 28 TYR A N 1 ATOM 168 C CA . TYR A 1 28 ? 1.344 5.038 28.648 1.00 19.48 ? 28 TYR A CA 1 ATOM 169 C C . TYR A 1 28 ? 1.666 4.305 27.353 1.00 19.48 ? 28 TYR A C 1 ATOM 170 O O . TYR A 1 28 ? 2.110 4.920 26.412 1.00 19.68 ? 28 TYR A O 1 ATOM 171 C CB . TYR A 1 28 ? 2.540 5.912 29.086 1.00 20.00 ? 28 TYR A CB 1 ATOM 172 C CG . TYR A 1 28 ? 2.252 6.844 30.256 1.00 20.73 ? 28 TYR A CG 1 ATOM 173 C CD1 . TYR A 1 28 ? 0.970 7.434 30.429 1.00 23.40 ? 28 TYR A CD1 1 ATOM 174 C CD2 . TYR A 1 28 ? 3.228 7.133 31.191 1.00 21.22 ? 28 TYR A CD2 1 ATOM 175 C CE1 . TYR A 1 28 ? 0.689 8.272 31.513 1.00 21.62 ? 28 TYR A CE1 1 ATOM 176 C CE2 . TYR A 1 28 ? 2.958 7.995 32.291 1.00 22.57 ? 28 TYR A CE2 1 ATOM 177 C CZ . TYR A 1 28 ? 1.693 8.542 32.440 1.00 23.05 ? 28 TYR A CZ 1 ATOM 178 O OH . TYR A 1 28 ? 1.442 9.380 33.497 1.00 23.23 ? 28 TYR A OH 1 ATOM 179 N N . ALA A 1 29 ? 1.459 2.988 27.311 1.00 19.63 ? 29 ALA A N 1 ATOM 180 C CA . ALA A 1 29 ? 1.733 2.224 26.095 1.00 19.61 ? 29 ALA A CA 1 ATOM 181 C C . ALA A 1 29 ? 0.541 2.287 25.188 1.00 20.10 ? 29 ALA A C 1 ATOM 182 O O . ALA A 1 29 ? -0.610 2.181 25.642 1.00 21.20 ? 29 ALA A O 1 ATOM 183 C CB . ALA A 1 29 ? 2.063 0.791 26.393 1.00 19.26 ? 29 ALA A CB 1 ATOM 184 N N . PRO A 1 30 ? 0.793 2.472 23.894 1.00 20.23 ? 30 PRO A N 1 ATOM 185 C CA . PRO A 1 30 ? -0.326 2.444 22.937 1.00 19.15 ? 30 PRO A CA 1 ATOM 186 C C . PRO A 1 30 ? -0.909 1.064 22.909 1.00 18.39 ? 30 PRO A C 1 ATOM 187 O O . PRO A 1 30 ? -0.157 0.087 23.090 1.00 18.54 ? 30 PRO A O 1 ATOM 188 C CB . PRO A 1 30 ? 0.337 2.728 21.600 1.00 19.86 ? 30 PRO A CB 1 ATOM 189 C CG . PRO A 1 30 ? 1.839 2.617 21.817 1.00 20.07 ? 30 PRO A CG 1 ATOM 190 C CD . PRO A 1 30 ? 2.127 2.371 23.256 1.00 20.40 ? 30 PRO A CD 1 ATOM 191 N N . PHE A 1 31 ? -2.232 0.945 22.748 1.00 17.93 ? 31 PHE A N 1 ATOM 192 C CA . PHE A 1 31 ? -2.821 -0.403 22.565 1.00 17.04 ? 31 PHE A CA 1 ATOM 193 C C . PHE A 1 31 ? -1.965 -1.345 21.682 1.00 16.84 ? 31 PHE A C 1 ATOM 194 O O . PHE A 1 31 ? -1.569 -0.977 20.592 1.00 16.12 ? 31 PHE A O 1 ATOM 195 C CB . PHE A 1 31 ? -4.191 -0.333 21.922 1.00 16.84 ? 31 PHE A CB 1 ATOM 196 C CG . PHE A 1 31 ? -4.728 -1.688 21.574 1.00 16.74 ? 31 PHE A CG 1 ATOM 197 C CD1 . PHE A 1 31 ? -5.084 -2.573 22.581 1.00 15.81 ? 31 PHE A CD1 1 ATOM 198 C CD2 . PHE A 1 31 ? -4.850 -2.098 20.250 1.00 17.10 ? 31 PHE A CD2 1 ATOM 199 C CE1 . PHE A 1 31 ? -5.568 -3.861 22.264 1.00 17.09 ? 31 PHE A CE1 1 ATOM 200 C CE2 . PHE A 1 31 ? -5.339 -3.383 19.919 1.00 14.91 ? 31 PHE A CE2 1 ATOM 201 C CZ . PHE A 1 31 ? -5.682 -4.258 20.918 1.00 15.51 ? 31 PHE A CZ 1 ATOM 202 N N . PHE A 1 32 ? -1.729 -2.569 22.151 1.00 17.50 ? 32 PHE A N 1 ATOM 203 C CA . PHE A 1 32 ? -1.135 -3.623 21.329 1.00 18.11 ? 32 PHE A CA 1 ATOM 204 C C . PHE A 1 32 ? -1.841 -4.898 21.648 1.00 18.44 ? 32 PHE A C 1 ATOM 205 O O . PHE A 1 32 ? -1.923 -5.257 22.802 1.00 18.59 ? 32 PHE A O 1 ATOM 206 C CB . PHE A 1 32 ? 0.401 -3.750 21.519 1.00 18.18 ? 32 PHE A CB 1 ATOM 207 C CG . PHE A 1 32 ? 0.827 -4.017 22.953 1.00 19.06 ? 32 PHE A CG 1 ATOM 208 C CD1 . PHE A 1 32 ? 0.969 -2.959 23.860 1.00 19.30 ? 32 PHE A CD1 1 ATOM 209 C CD2 . PHE A 1 32 ? 1.084 -5.328 23.380 1.00 20.98 ? 32 PHE A CD2 1 ATOM 210 C CE1 . PHE A 1 32 ? 1.315 -3.199 25.180 1.00 21.75 ? 32 PHE A CE1 1 ATOM 211 C CE2 . PHE A 1 32 ? 1.440 -5.597 24.700 1.00 22.86 ? 32 PHE A CE2 1 ATOM 212 C CZ . PHE A 1 32 ? 1.551 -4.537 25.607 1.00 23.30 ? 32 PHE A CZ 1 ATOM 213 N N . SER A 1 33 ? -2.367 -5.575 20.614 1.00 19.04 ? 33 SER A N 1 ATOM 214 C CA . SER A 1 33 ? -3.130 -6.803 20.788 1.00 18.86 ? 33 SER A CA 1 ATOM 215 C C . SER A 1 33 ? -2.351 -7.978 21.370 1.00 19.83 ? 33 SER A C 1 ATOM 216 O O . SER A 1 33 ? -1.278 -8.296 20.931 1.00 19.92 ? 33 SER A O 1 ATOM 217 C CB . SER A 1 33 ? -3.751 -7.267 19.470 1.00 18.80 ? 33 SER A CB 1 ATOM 218 O OG . SER A 1 33 ? -4.353 -8.567 19.632 1.00 16.15 ? 33 SER A OG 1 ATOM 219 N N . LEU A 1 34 ? -2.954 -8.657 22.333 1.00 20.65 ? 34 LEU A N 1 ATOM 220 C CA . LEU A 1 34 ? -2.304 -9.766 22.967 1.00 21.09 ? 34 LEU A CA 1 ATOM 221 C C . LEU A 1 34 ? -2.775 -11.092 22.400 1.00 22.50 ? 34 LEU A C 1 ATOM 222 O O . LEU A 1 34 ? -2.643 -12.125 23.049 1.00 21.86 ? 34 LEU A O 1 ATOM 223 C CB . LEU A 1 34 ? -2.582 -9.695 24.473 1.00 20.67 ? 34 LEU A CB 1 ATOM 224 C CG . LEU A 1 34 ? -1.948 -8.480 25.169 1.00 18.97 ? 34 LEU A CG 1 ATOM 225 C CD1 . LEU A 1 34 ? -2.402 -8.379 26.587 1.00 18.64 ? 34 LEU A CD1 1 ATOM 226 C CD2 . LEU A 1 34 ? -0.445 -8.612 25.084 1.00 19.65 ? 34 LEU A CD2 1 ATOM 227 N N . ALA A 1 35 ? -3.342 -11.066 21.195 1.00 24.33 ? 35 ALA A N 1 ATOM 228 C CA . ALA A 1 35 ? -4.001 -12.267 20.654 1.00 26.29 ? 35 ALA A CA 1 ATOM 229 C C . ALA A 1 35 ? -3.017 -13.429 20.531 1.00 27.94 ? 35 ALA A C 1 ATOM 230 O O . ALA A 1 35 ? -3.374 -14.553 20.857 1.00 28.73 ? 35 ALA A O 1 ATOM 231 C CB . ALA A 1 35 ? -4.714 -11.980 19.288 1.00 25.53 ? 35 ALA A CB 1 ATOM 232 N N . ASN A 1 36 ? -1.794 -13.140 20.070 1.00 30.21 ? 36 ASN A N 1 ATOM 233 C CA . ASN A 1 36 ? -0.683 -14.096 19.963 1.00 32.78 ? 36 ASN A CA 1 ATOM 234 C C . ASN A 1 36 ? -0.188 -14.637 21.287 1.00 33.61 ? 36 ASN A C 1 ATOM 235 O O . ASN A 1 36 ? 0.508 -15.662 21.345 1.00 33.80 ? 36 ASN A O 1 ATOM 236 C CB . ASN A 1 36 ? 0.502 -13.393 19.350 1.00 33.51 ? 36 ASN A CB 1 ATOM 237 C CG . ASN A 1 36 ? 0.346 -13.205 17.878 1.00 37.95 ? 36 ASN A CG 1 ATOM 238 O OD1 . ASN A 1 36 ? -0.650 -13.650 17.270 1.00 41.57 ? 36 ASN A OD1 1 ATOM 239 N ND2 . ASN A 1 36 ? 1.332 -12.539 17.268 1.00 41.85 ? 36 ASN A ND2 1 ATOM 240 N N . GLU A 1 37 ? -0.520 -13.911 22.351 1.00 34.39 ? 37 GLU A N 1 ATOM 241 C CA . GLU A 1 37 ? -0.160 -14.293 23.701 1.00 35.10 ? 37 GLU A CA 1 ATOM 242 C C . GLU A 1 37 ? -1.251 -15.104 24.400 1.00 35.12 ? 37 GLU A C 1 ATOM 243 O O . GLU A 1 37 ? -1.049 -15.596 25.517 1.00 34.95 ? 37 GLU A O 1 ATOM 244 C CB . GLU A 1 37 ? 0.162 -13.037 24.493 1.00 35.55 ? 37 GLU A CB 1 ATOM 245 C CG . GLU A 1 37 ? 1.380 -12.268 23.967 1.00 38.43 ? 37 GLU A CG 1 ATOM 246 C CD . GLU A 1 37 ? 2.689 -12.981 24.253 1.00 41.93 ? 37 GLU A CD 1 ATOM 247 O OE1 . GLU A 1 37 ? 2.677 -14.053 24.913 1.00 43.28 ? 37 GLU A OE1 1 ATOM 248 O OE2 . GLU A 1 37 ? 3.739 -12.470 23.813 1.00 45.15 ? 37 GLU A OE2 1 ATOM 249 N N . SER A 1 38 ? -2.396 -15.251 23.733 1.00 35.02 ? 38 SER A N 1 ATOM 250 C CA . SER A 1 38 ? -3.527 -15.971 24.298 1.00 35.43 ? 38 SER A CA 1 ATOM 251 C C . SER A 1 38 ? -3.283 -17.471 24.166 1.00 36.26 ? 38 SER A C 1 ATOM 252 O O . SER A 1 38 ? -3.125 -18.000 23.036 1.00 37.24 ? 38 SER A O 1 ATOM 253 C CB . SER A 1 38 ? -4.820 -15.583 23.575 1.00 35.41 ? 38 SER A CB 1 ATOM 254 O OG . SER A 1 38 ? -5.969 -15.931 24.332 1.00 34.37 ? 38 SER A OG 1 ATOM 255 N N . VAL A 1 39 ? -3.246 -18.175 25.293 1.00 35.93 ? 39 VAL A N 1 ATOM 256 C CA . VAL A 1 39 ? -3.098 -19.613 25.218 1.00 35.55 ? 39 VAL A CA 1 ATOM 257 C C . VAL A 1 39 ? -4.416 -20.235 24.774 1.00 35.38 ? 39 VAL A C 1 ATOM 258 O O . VAL A 1 39 ? -4.426 -21.254 24.076 1.00 35.82 ? 39 VAL A O 1 ATOM 259 C CB . VAL A 1 39 ? -2.578 -20.197 26.538 1.00 35.89 ? 39 VAL A CB 1 ATOM 260 C CG1 . VAL A 1 39 ? -2.523 -21.731 26.499 1.00 34.80 ? 39 VAL A CG1 1 ATOM 261 C CG2 . VAL A 1 39 ? -1.187 -19.592 26.842 1.00 36.85 ? 39 VAL A CG2 1 ATOM 262 N N . ILE A 1 40 ? -5.537 -19.638 25.163 1.00 34.81 ? 40 ILE A N 1 ATOM 263 C CA . ILE A 1 40 ? -6.826 -20.123 24.660 1.00 34.37 ? 40 ILE A CA 1 ATOM 264 C C . ILE A 1 40 ? -7.151 -19.336 23.399 1.00 34.88 ? 40 ILE A C 1 ATOM 265 O O . ILE A 1 40 ? -6.856 -18.125 23.311 1.00 34.57 ? 40 ILE A O 1 ATOM 266 C CB . ILE A 1 40 ? -7.942 -20.004 25.724 1.00 34.15 ? 40 ILE A CB 1 ATOM 267 C CG1 . ILE A 1 40 ? -7.624 -20.900 26.935 1.00 33.48 ? 40 ILE A CG1 1 ATOM 268 C CG2 . ILE A 1 40 ? -9.306 -20.319 25.136 1.00 32.47 ? 40 ILE A CG2 1 ATOM 269 C CD1 . ILE A 1 40 ? -8.201 -20.383 28.281 1.00 31.03 ? 40 ILE A CD1 1 ATOM 270 N N . SER A 1 41 ? -7.719 -20.016 22.411 1.00 35.56 ? 41 SER A N 1 ATOM 271 C CA . SER A 1 41 ? -8.005 -19.360 21.138 1.00 36.89 ? 41 SER A CA 1 ATOM 272 C C . SER A 1 41 ? -9.149 -18.363 21.311 1.00 37.26 ? 41 SER A C 1 ATOM 273 O O . SER A 1 41 ? -10.190 -18.695 21.900 1.00 37.58 ? 41 SER A O 1 ATOM 274 C CB . SER A 1 41 ? -8.303 -20.369 20.016 1.00 37.02 ? 41 SER A CB 1 ATOM 275 O OG . SER A 1 41 ? -8.394 -19.705 18.759 1.00 38.23 ? 41 SER A OG 1 ATOM 276 N N . PRO A 1 42 ? -8.939 -17.126 20.835 1.00 38.11 ? 42 PRO A N 1 ATOM 277 C CA . PRO A 1 42 ? -10.006 -16.118 20.846 1.00 38.82 ? 42 PRO A CA 1 ATOM 278 C C . PRO A 1 42 ? -11.184 -16.451 19.903 1.00 39.35 ? 42 PRO A C 1 ATOM 279 O O . PRO A 1 42 ? -12.314 -16.009 20.153 1.00 39.57 ? 42 PRO A O 1 ATOM 280 C CB . PRO A 1 42 ? -9.281 -14.822 20.436 1.00 38.74 ? 42 PRO A CB 1 ATOM 281 C CG . PRO A 1 42 ? -8.072 -15.299 19.645 1.00 38.24 ? 42 PRO A CG 1 ATOM 282 C CD . PRO A 1 42 ? -7.664 -16.591 20.301 1.00 37.96 ? 42 PRO A CD 1 ATOM 283 N N . GLU A 1 43 ? -10.934 -17.223 18.847 1.00 39.98 ? 43 GLU A N 1 ATOM 284 C CA . GLU A 1 43 ? -12.019 -17.669 17.956 1.00 41.13 ? 43 GLU A CA 1 ATOM 285 C C . GLU A 1 43 ? -13.223 -18.295 18.679 1.00 41.38 ? 43 GLU A C 1 ATOM 286 O O . GLU A 1 43 ? -13.092 -18.961 19.732 1.00 41.41 ? 43 GLU A O 1 ATOM 287 C CB . GLU A 1 43 ? -11.514 -18.630 16.883 1.00 40.97 ? 43 GLU A CB 1 ATOM 288 C CG . GLU A 1 43 ? -10.986 -17.932 15.648 1.00 43.74 ? 43 GLU A CG 1 ATOM 289 C CD . GLU A 1 43 ? -9.484 -17.710 15.715 1.00 48.57 ? 43 GLU A CD 1 ATOM 290 O OE1 . GLU A 1 43 ? -8.722 -18.550 15.169 1.00 51.31 ? 43 GLU A OE1 1 ATOM 291 O OE2 . GLU A 1 43 ? -9.048 -16.712 16.331 1.00 49.11 ? 43 GLU A OE2 1 ATOM 292 N N . VAL A 1 44 ? -14.385 -18.065 18.087 1.00 41.17 ? 44 VAL A N 1 ATOM 293 C CA . VAL A 1 44 ? -15.639 -18.663 18.516 1.00 41.71 ? 44 VAL A CA 1 ATOM 294 C C . VAL A 1 44 ? -15.597 -20.159 18.198 1.00 41.58 ? 44 VAL A C 1 ATOM 295 O O . VAL A 1 44 ? -15.332 -20.542 17.049 1.00 41.78 ? 44 VAL A O 1 ATOM 296 C CB . VAL A 1 44 ? -16.817 -18.029 17.732 1.00 42.09 ? 44 VAL A CB 1 ATOM 297 C CG1 . VAL A 1 44 ? -18.177 -18.444 18.311 1.00 42.76 ? 44 VAL A CG1 1 ATOM 298 C CG2 . VAL A 1 44 ? -16.671 -16.509 17.689 1.00 42.52 ? 44 VAL A CG2 1 ATOM 299 N N . PRO A 1 45 ? -15.856 -21.017 19.205 1.00 41.21 ? 45 PRO A N 1 ATOM 300 C CA . PRO A 1 45 ? -15.768 -22.437 18.889 1.00 40.73 ? 45 PRO A CA 1 ATOM 301 C C . PRO A 1 45 ? -16.877 -22.864 17.941 1.00 40.48 ? 45 PRO A C 1 ATOM 302 O O . PRO A 1 45 ? -17.925 -22.197 17.839 1.00 39.86 ? 45 PRO A O 1 ATOM 303 C CB . PRO A 1 45 ? -15.933 -23.120 20.262 1.00 40.75 ? 45 PRO A CB 1 ATOM 304 C CG . PRO A 1 45 ? -15.511 -22.109 21.236 1.00 40.45 ? 45 PRO A CG 1 ATOM 305 C CD . PRO A 1 45 ? -15.952 -20.790 20.660 1.00 41.07 ? 45 PRO A CD 1 ATOM 306 N N . ALA A 1 46 ? -16.635 -23.978 17.257 1.00 39.80 ? 46 ALA A N 1 ATOM 307 C CA . ALA A 1 46 ? -17.640 -24.564 16.396 1.00 39.16 ? 46 ALA A CA 1 ATOM 308 C C . ALA A 1 46 ? -18.815 -25.014 17.249 1.00 38.04 ? 46 ALA A C 1 ATOM 309 O O . ALA A 1 46 ? -18.635 -25.430 18.391 1.00 38.54 ? 46 ALA A O 1 ATOM 310 C CB . ALA A 1 46 ? -17.050 -25.744 15.623 1.00 39.72 ? 46 ALA A CB 1 ATOM 311 N N . GLY A 1 47 ? -20.009 -24.924 16.683 1.00 36.97 ? 47 GLY A N 1 ATOM 312 C CA . GLY A 1 47 ? -21.240 -25.281 17.376 1.00 35.79 ? 47 GLY A CA 1 ATOM 313 C C . GLY A 1 47 ? -21.758 -24.111 18.190 1.00 34.96 ? 47 GLY A C 1 ATOM 314 O O . GLY A 1 47 ? -22.898 -24.150 18.654 1.00 35.20 ? 47 GLY A O 1 ATOM 315 N N . CYS A 1 48 ? -20.922 -23.071 18.323 1.00 33.50 ? 48 CYS A N 1 ATOM 316 C CA . CYS A 1 48 ? -21.185 -21.930 19.195 1.00 32.65 ? 48 CYS A CA 1 ATOM 317 C C . CYS A 1 48 ? -21.546 -20.629 18.456 1.00 31.56 ? 48 CYS A C 1 ATOM 318 O O . CYS A 1 48 ? -20.967 -20.293 17.395 1.00 31.29 ? 48 CYS A O 1 ATOM 319 C CB . CYS A 1 48 ? -19.966 -21.671 20.103 1.00 33.31 ? 48 CYS A CB 1 ATOM 320 S SG . CYS A 1 48 ? -19.640 -22.985 21.370 1.00 32.83 ? 48 CYS A SG 1 ATOM 321 N N . ARG A 1 49 ? -22.463 -19.878 19.055 1.00 29.25 ? 49 ARG A N 1 ATOM 322 C CA A ARG A 1 49 ? -22.950 -18.616 18.510 0.50 28.12 ? 49 ARG A CA 1 ATOM 323 C CA B ARG A 1 49 ? -22.774 -18.562 18.520 0.50 27.59 ? 49 ARG A CA 1 ATOM 324 C C . ARG A 1 49 ? -22.946 -17.486 19.574 1.00 26.81 ? 49 ARG A C 1 ATOM 325 O O . ARG A 1 49 ? -23.610 -17.645 20.603 1.00 26.31 ? 49 ARG A O 1 ATOM 326 C CB A ARG A 1 49 ? -24.369 -18.890 17.963 0.50 28.10 ? 49 ARG A CB 1 ATOM 327 C CB B ARG A 1 49 ? -23.943 -18.581 17.519 0.50 27.50 ? 49 ARG A CB 1 ATOM 328 C CG A ARG A 1 49 ? -25.128 -17.722 17.377 0.50 29.15 ? 49 ARG A CG 1 ATOM 329 C CG B ARG A 1 49 ? -23.622 -17.744 16.274 0.50 25.48 ? 49 ARG A CG 1 ATOM 330 C CD A ARG A 1 49 ? -26.581 -18.121 17.067 0.50 29.85 ? 49 ARG A CD 1 ATOM 331 C CD B ARG A 1 49 ? -24.789 -17.620 15.323 0.50 23.01 ? 49 ARG A CD 1 ATOM 332 N NE A ARG A 1 49 ? -27.230 -18.842 18.162 0.50 28.64 ? 49 ARG A NE 1 ATOM 333 N NE B ARG A 1 49 ? -24.320 -17.653 13.948 0.50 20.04 ? 49 ARG A NE 1 ATOM 334 C CZ A ARG A 1 49 ? -28.376 -18.478 18.727 0.50 29.41 ? 49 ARG A CZ 1 ATOM 335 C CZ B ARG A 1 49 ? -24.178 -18.779 13.261 0.50 18.27 ? 49 ARG A CZ 1 ATOM 336 N NH1 A ARG A 1 49 ? -29.020 -17.390 18.319 0.50 30.18 ? 49 ARG A NH1 1 ATOM 337 N NH1 B ARG A 1 49 ? -24.474 -19.950 13.833 0.50 18.60 ? 49 ARG A NH1 1 ATOM 338 N NH2 A ARG A 1 49 ? -28.887 -19.207 19.705 0.50 29.43 ? 49 ARG A NH2 1 ATOM 339 N NH2 B ARG A 1 49 ? -23.735 -18.740 12.020 0.50 14.68 ? 49 ARG A NH2 1 ATOM 340 N N . VAL A 1 50 ? -22.258 -16.370 19.315 1.00 25.75 ? 50 VAL A N 1 ATOM 341 C CA . VAL A 1 50 ? -22.259 -15.208 20.211 1.00 23.69 ? 50 VAL A CA 1 ATOM 342 C C . VAL A 1 50 ? -23.634 -14.495 20.187 1.00 23.50 ? 50 VAL A C 1 ATOM 343 O O . VAL A 1 50 ? -24.142 -14.117 19.125 1.00 23.05 ? 50 VAL A O 1 ATOM 344 C CB . VAL A 1 50 ? -21.172 -14.187 19.823 1.00 24.53 ? 50 VAL A CB 1 ATOM 345 C CG1 . VAL A 1 50 ? -21.021 -13.105 20.894 1.00 23.44 ? 50 VAL A CG1 1 ATOM 346 C CG2 . VAL A 1 50 ? -19.807 -14.851 19.531 1.00 23.96 ? 50 VAL A CG2 1 ATOM 347 N N . THR A 1 51 ? -24.235 -14.309 21.355 1.00 22.65 ? 51 THR A N 1 ATOM 348 C CA . THR A 1 51 ? -25.580 -13.729 21.451 1.00 22.38 ? 51 THR A CA 1 ATOM 349 C C . THR A 1 51 ? -25.642 -12.424 22.278 1.00 21.66 ? 51 THR A C 1 ATOM 350 O O . THR A 1 51 ? -26.739 -11.930 22.579 1.00 21.74 ? 51 THR A O 1 ATOM 351 C CB . THR A 1 51 ? -26.555 -14.752 22.060 1.00 23.06 ? 51 THR A CB 1 ATOM 352 O OG1 . THR A 1 51 ? -26.149 -15.081 23.405 1.00 23.60 ? 51 THR A OG1 1 ATOM 353 C CG2 . THR A 1 51 ? -26.572 -16.031 21.233 1.00 23.57 ? 51 THR A CG2 1 ATOM 354 N N . PHE A 1 52 ? -24.459 -11.902 22.652 1.00 20.72 ? 52 PHE A N 1 ATOM 355 C CA . PHE A 1 52 ? -24.264 -10.717 23.576 1.00 19.46 ? 52 PHE A CA 1 ATOM 356 C C . PHE A 1 52 ? -22.825 -10.269 23.389 1.00 18.53 ? 52 PHE A C 1 ATOM 357 O O . PHE A 1 52 ? -21.917 -11.103 23.366 1.00 18.42 ? 52 PHE A O 1 ATOM 358 C CB . PHE A 1 52 ? -24.479 -11.121 25.055 1.00 19.16 ? 52 PHE A CB 1 ATOM 359 C CG . PHE A 1 52 ? -24.308 -9.991 26.070 1.00 18.66 ? 52 PHE A CG 1 ATOM 360 C CD1 . PHE A 1 52 ? -23.055 -9.676 26.583 1.00 15.38 ? 52 PHE A CD1 1 ATOM 361 C CD2 . PHE A 1 52 ? -25.434 -9.277 26.562 1.00 18.69 ? 52 PHE A CD2 1 ATOM 362 C CE1 . PHE A 1 52 ? -22.899 -8.650 27.490 1.00 15.15 ? 52 PHE A CE1 1 ATOM 363 C CE2 . PHE A 1 52 ? -25.283 -8.243 27.506 1.00 15.89 ? 52 PHE A CE2 1 ATOM 364 C CZ . PHE A 1 52 ? -24.015 -7.928 27.945 1.00 16.58 ? 52 PHE A CZ 1 ATOM 365 N N . ALA A 1 53 ? -22.620 -8.972 23.211 1.00 17.51 ? 53 ALA A N 1 ATOM 366 C CA . ALA A 1 53 ? -21.281 -8.400 23.300 1.00 17.00 ? 53 ALA A CA 1 ATOM 367 C C . ALA A 1 53 ? -21.298 -7.007 23.919 1.00 15.61 ? 53 ALA A C 1 ATOM 368 O O . ALA A 1 53 ? -21.968 -6.116 23.442 1.00 14.96 ? 53 ALA A O 1 ATOM 369 C CB . ALA A 1 53 ? -20.529 -8.421 21.907 1.00 16.62 ? 53 ALA A CB 1 ATOM 370 N N . GLN A 1 54 ? -20.582 -6.870 25.033 1.00 15.48 ? 54 GLN A N 1 ATOM 371 C CA . GLN A 1 54 ? -20.312 -5.594 25.712 1.00 14.40 ? 54 GLN A CA 1 ATOM 372 C C . GLN A 1 54 ? -18.834 -5.317 25.563 1.00 13.99 ? 54 GLN A C 1 ATOM 373 O O . GLN A 1 54 ? -18.017 -6.215 25.764 1.00 14.00 ? 54 GLN A O 1 ATOM 374 C CB . GLN A 1 54 ? -20.665 -5.646 27.204 1.00 14.12 ? 54 GLN A CB 1 ATOM 375 C CG . GLN A 1 54 ? -20.361 -4.318 27.991 1.00 15.95 ? 54 GLN A CG 1 ATOM 376 C CD . GLN A 1 54 ? -21.256 -4.129 29.224 1.00 19.20 ? 54 GLN A CD 1 ATOM 377 O OE1 . GLN A 1 54 ? -22.489 -3.988 29.112 1.00 20.64 ? 54 GLN A OE1 1 ATOM 378 N NE2 . GLN A 1 54 ? -20.635 -4.102 30.412 1.00 17.07 ? 54 GLN A NE2 1 ATOM 379 N N . VAL A 1 55 ? -18.495 -4.089 25.187 1.00 13.92 ? 55 VAL A N 1 ATOM 380 C CA . VAL A 1 55 ? -17.100 -3.658 25.170 1.00 14.60 ? 55 VAL A CA 1 ATOM 381 C C . VAL A 1 55 ? -16.917 -2.506 26.162 1.00 14.72 ? 55 VAL A C 1 ATOM 382 O O . VAL A 1 55 ? -17.705 -1.569 26.159 1.00 15.25 ? 55 VAL A O 1 ATOM 383 C CB . VAL A 1 55 ? -16.635 -3.220 23.789 1.00 14.41 ? 55 VAL A CB 1 ATOM 384 C CG1 . VAL A 1 55 ? -17.636 -2.203 23.184 1.00 13.64 ? 55 VAL A CG1 1 ATOM 385 C CG2 . VAL A 1 55 ? -15.211 -2.631 23.869 1.00 13.83 ? 55 VAL A CG2 1 ATOM 386 N N . LEU A 1 56 ? -15.930 -2.623 27.040 1.00 14.37 ? 56 LEU A N 1 ATOM 387 C CA . LEU A 1 56 ? -15.499 -1.500 27.873 1.00 14.44 ? 56 LEU A CA 1 ATOM 388 C C . LEU A 1 56 ? -14.152 -0.971 27.363 1.00 15.35 ? 56 LEU A C 1 ATOM 389 O O . LEU A 1 56 ? -13.178 -1.739 27.190 1.00 15.86 ? 56 LEU A O 1 ATOM 390 C CB . LEU A 1 56 ? -15.446 -1.909 29.355 1.00 14.71 ? 56 LEU A CB 1 ATOM 391 C CG . LEU A 1 56 ? -14.970 -0.842 30.383 1.00 13.45 ? 56 LEU A CG 1 ATOM 392 C CD1 . LEU A 1 56 ? -15.865 0.397 30.466 1.00 6.90 ? 56 LEU A CD1 1 ATOM 393 C CD2 . LEU A 1 56 ? -14.879 -1.492 31.709 1.00 11.04 ? 56 LEU A CD2 1 ATOM 394 N N . SER A 1 57 ? -14.088 0.327 27.063 1.00 16.20 ? 57 SER A N 1 ATOM 395 C CA . SER A 1 57 ? -12.909 0.846 26.386 1.00 15.97 ? 57 SER A CA 1 ATOM 396 C C . SER A 1 57 ? -12.347 2.057 27.075 1.00 17.13 ? 57 SER A C 1 ATOM 397 O O . SER A 1 57 ? -13.096 2.881 27.629 1.00 18.60 ? 57 SER A O 1 ATOM 398 C CB . SER A 1 57 ? -13.225 1.168 24.911 1.00 16.73 ? 57 SER A CB 1 ATOM 399 O OG . SER A 1 57 ? -12.087 1.690 24.220 1.00 14.89 ? 57 SER A OG 1 ATOM 400 N N . ARG A 1 58 ? -11.015 2.186 27.049 1.00 17.69 ? 58 ARG A N 1 ATOM 401 C CA . ARG A 1 58 ? -10.371 3.352 27.612 1.00 16.94 ? 58 ARG A CA 1 ATOM 402 C C . ARG A 1 58 ? -10.341 4.381 26.516 1.00 17.17 ? 58 ARG A C 1 ATOM 403 O O . ARG A 1 58 ? -10.514 4.025 25.366 1.00 16.91 ? 58 ARG A O 1 ATOM 404 C CB . ARG A 1 58 ? -8.950 3.019 28.043 1.00 17.40 ? 58 ARG A CB 1 ATOM 405 C CG . ARG A 1 58 ? -8.273 4.171 28.807 1.00 15.21 ? 58 ARG A CG 1 ATOM 406 C CD . ARG A 1 58 ? -6.931 3.785 29.304 1.00 13.63 ? 58 ARG A CD 1 ATOM 407 N NE . ARG A 1 58 ? -6.200 4.974 29.740 1.00 15.86 ? 58 ARG A NE 1 ATOM 408 C CZ . ARG A 1 58 ? -4.873 5.062 29.857 1.00 11.70 ? 58 ARG A CZ 1 ATOM 409 N NH1 . ARG A 1 58 ? -4.096 4.022 29.579 1.00 10.04 ? 58 ARG A NH1 1 ATOM 410 N NH2 . ARG A 1 58 ? -4.341 6.218 30.218 1.00 8.81 ? 58 ARG A NH2 1 ATOM 411 N N . HIS A 1 59 ? -10.119 5.650 26.852 1.00 17.18 ? 59 HIS A N 1 ATOM 412 C CA . HIS A 1 59 ? -9.829 6.635 25.820 1.00 16.98 ? 59 HIS A CA 1 ATOM 413 C C . HIS A 1 59 ? -8.519 6.319 25.137 1.00 16.98 ? 59 HIS A C 1 ATOM 414 O O . HIS A 1 59 ? -7.789 5.416 25.537 1.00 16.29 ? 59 HIS A O 1 ATOM 415 C CB . HIS A 1 59 ? -9.798 8.066 26.346 1.00 16.90 ? 59 HIS A CB 1 ATOM 416 C CG . HIS A 1 59 ? -8.810 8.267 27.440 1.00 16.58 ? 59 HIS A CG 1 ATOM 417 N ND1 . HIS A 1 59 ? -7.455 8.415 27.205 1.00 15.61 ? 59 HIS A ND1 1 ATOM 418 C CD2 . HIS A 1 59 ? -8.980 8.351 28.781 1.00 11.99 ? 59 HIS A CD2 1 ATOM 419 C CE1 . HIS A 1 59 ? -6.833 8.568 28.361 1.00 14.02 ? 59 HIS A CE1 1 ATOM 420 N NE2 . HIS A 1 59 ? -7.735 8.536 29.329 1.00 13.63 ? 59 HIS A NE2 1 ATOM 421 N N . GLY A 1 60 ? -8.257 7.055 24.062 1.00 17.37 ? 60 GLY A N 1 ATOM 422 C CA . GLY A 1 60 ? -7.055 6.841 23.275 1.00 18.04 ? 60 GLY A CA 1 ATOM 423 C C . GLY A 1 60 ? -5.900 7.599 23.875 1.00 18.38 ? 60 GLY A C 1 ATOM 424 O O . GLY A 1 60 ? -6.066 8.303 24.857 1.00 18.50 ? 60 GLY A O 1 ATOM 425 N N . ALA A 1 61 ? -4.737 7.436 23.259 1.00 19.18 ? 61 ALA A N 1 ATOM 426 C CA . ALA A 1 61 ? -3.547 8.186 23.561 1.00 20.29 ? 61 ALA A CA 1 ATOM 427 C C . ALA A 1 61 ? -3.796 9.689 23.664 1.00 22.12 ? 61 ALA A C 1 ATOM 428 O O . ALA A 1 61 ? -4.488 10.286 22.833 1.00 22.99 ? 61 ALA A O 1 ATOM 429 C CB . ALA A 1 61 ? -2.502 7.881 22.513 1.00 19.89 ? 61 ALA A CB 1 ATOM 430 N N . ARG A 1 62 ? -3.254 10.302 24.706 1.00 23.61 ? 62 ARG A N 1 ATOM 431 C CA . ARG A 1 62 ? -3.497 11.719 24.963 1.00 25.09 ? 62 ARG A CA 1 ATOM 432 C C . ARG A 1 62 ? -2.194 12.500 25.153 1.00 25.02 ? 62 ARG A C 1 ATOM 433 O O . ARG A 1 62 ? -1.174 11.948 25.514 1.00 26.03 ? 62 ARG A O 1 ATOM 434 C CB . ARG A 1 62 ? -4.405 11.902 26.198 1.00 25.07 ? 62 ARG A CB 1 ATOM 435 C CG . ARG A 1 62 ? -3.788 11.333 27.510 1.00 25.97 ? 62 ARG A CG 1 ATOM 436 C CD . ARG A 1 62 ? -4.449 11.888 28.750 1.00 26.92 ? 62 ARG A CD 1 ATOM 437 N NE . ARG A 1 62 ? -3.906 11.384 30.027 1.00 28.76 ? 62 ARG A NE 1 ATOM 438 C CZ . ARG A 1 62 ? -2.693 11.656 30.531 1.00 30.35 ? 62 ARG A CZ 1 ATOM 439 N NH1 . ARG A 1 62 ? -1.795 12.371 29.859 1.00 31.54 ? 62 ARG A NH1 1 ATOM 440 N NH2 . ARG A 1 62 ? -2.352 11.186 31.724 1.00 30.17 ? 62 ARG A NH2 1 ATOM 441 N N . TYR A 1 63 ? -2.247 13.790 24.906 1.00 25.37 ? 63 TYR A N 1 ATOM 442 C CA . TYR A 1 63 ? -1.238 14.697 25.424 1.00 26.65 ? 63 TYR A CA 1 ATOM 443 C C . TYR A 1 63 ? -1.126 14.636 26.957 1.00 27.82 ? 63 TYR A C 1 ATOM 444 O O . TYR A 1 63 ? -2.100 14.244 27.641 1.00 27.64 ? 63 TYR A O 1 ATOM 445 C CB . TYR A 1 63 ? -1.585 16.111 25.018 1.00 26.34 ? 63 TYR A CB 1 ATOM 446 C CG . TYR A 1 63 ? -1.480 16.326 23.534 1.00 25.65 ? 63 TYR A CG 1 ATOM 447 C CD1 . TYR A 1 63 ? -0.276 16.050 22.854 1.00 23.10 ? 63 TYR A CD1 1 ATOM 448 C CD2 . TYR A 1 63 ? -2.577 16.789 22.800 1.00 24.95 ? 63 TYR A CD2 1 ATOM 449 C CE1 . TYR A 1 63 ? -0.167 16.247 21.470 1.00 23.95 ? 63 TYR A CE1 1 ATOM 450 C CE2 . TYR A 1 63 ? -2.484 16.979 21.402 1.00 26.17 ? 63 TYR A CE2 1 ATOM 451 C CZ . TYR A 1 63 ? -1.276 16.720 20.761 1.00 27.21 ? 63 TYR A CZ 1 ATOM 452 O OH . TYR A 1 63 ? -1.183 16.911 19.401 1.00 32.13 ? 63 TYR A OH 1 ATOM 453 N N . PRO A 1 64 ? 0.058 15.009 27.501 1.00 28.49 ? 64 PRO A N 1 ATOM 454 C CA . PRO A 1 64 ? 0.240 15.068 28.957 1.00 29.49 ? 64 PRO A CA 1 ATOM 455 C C . PRO A 1 64 ? -0.755 16.031 29.625 1.00 30.33 ? 64 PRO A C 1 ATOM 456 O O . PRO A 1 64 ? -1.202 16.992 29.008 1.00 30.18 ? 64 PRO A O 1 ATOM 457 C CB . PRO A 1 64 ? 1.679 15.577 29.113 1.00 29.42 ? 64 PRO A CB 1 ATOM 458 C CG . PRO A 1 64 ? 2.366 15.275 27.803 1.00 28.76 ? 64 PRO A CG 1 ATOM 459 C CD . PRO A 1 64 ? 1.283 15.397 26.770 1.00 28.52 ? 64 PRO A CD 1 ATOM 460 N N . THR A 1 65 ? -1.118 15.794 30.872 1.00 31.99 ? 65 THR A N 1 ATOM 461 C CA . THR A 1 65 ? -2.029 16.745 31.492 1.00 34.35 ? 65 THR A CA 1 ATOM 462 C C . THR A 1 65 ? -1.314 18.098 31.648 1.00 35.96 ? 65 THR A C 1 ATOM 463 O O . THR A 1 65 ? -0.070 18.169 31.550 1.00 36.58 ? 65 THR A O 1 ATOM 464 C CB . THR A 1 65 ? -2.556 16.303 32.850 1.00 34.32 ? 65 THR A CB 1 ATOM 465 O OG1 . THR A 1 65 ? -1.627 16.703 33.856 1.00 36.56 ? 65 THR A OG1 1 ATOM 466 C CG2 . THR A 1 65 ? -2.810 14.786 32.923 1.00 34.52 ? 65 THR A CG2 1 ATOM 467 N N . ASP A 1 66 ? -2.084 19.168 31.876 1.00 37.34 ? 66 ASP A N 1 ATOM 468 C CA . ASP A 1 66 ? -1.496 20.504 31.980 1.00 38.90 ? 66 ASP A CA 1 ATOM 469 C C . ASP A 1 66 ? -0.413 20.569 33.073 1.00 39.16 ? 66 ASP A C 1 ATOM 470 O O . ASP A 1 66 ? 0.721 20.981 32.830 1.00 39.34 ? 66 ASP A O 1 ATOM 471 C CB . ASP A 1 66 ? -2.575 21.545 32.218 1.00 39.38 ? 66 ASP A CB 1 ATOM 472 C CG . ASP A 1 66 ? -2.094 22.962 31.928 1.00 41.10 ? 66 ASP A CG 1 ATOM 473 O OD1 . ASP A 1 66 ? -1.639 23.218 30.778 1.00 44.05 ? 66 ASP A OD1 1 ATOM 474 O OD2 . ASP A 1 66 ? -2.184 23.807 32.858 1.00 41.04 ? 66 ASP A OD2 1 ATOM 475 N N . SER A 1 67 ? -0.777 20.111 34.260 1.00 40.09 ? 67 SER A N 1 ATOM 476 C CA . SER A 1 67 ? 0.156 19.866 35.348 1.00 40.77 ? 67 SER A CA 1 ATOM 477 C C . SER A 1 67 ? 1.501 19.304 34.868 1.00 41.21 ? 67 SER A C 1 ATOM 478 O O . SER A 1 67 ? 2.521 19.998 34.878 1.00 41.10 ? 67 SER A O 1 ATOM 479 C CB . SER A 1 67 ? -0.480 18.865 36.296 1.00 41.08 ? 67 SER A CB 1 ATOM 480 O OG . SER A 1 67 ? -0.243 19.242 37.632 1.00 42.40 ? 67 SER A OG 1 ATOM 481 N N . LYS A 1 68 ? 1.476 18.049 34.425 1.00 41.36 ? 68 LYS A N 1 ATOM 482 C CA . LYS A 1 68 ? 2.688 17.301 34.081 1.00 41.17 ? 68 LYS A CA 1 ATOM 483 C C . LYS A 1 68 ? 3.515 17.940 32.990 1.00 41.21 ? 68 LYS A C 1 ATOM 484 O O . LYS A 1 68 ? 4.747 17.921 33.051 1.00 40.84 ? 68 LYS A O 1 ATOM 485 C CB . LYS A 1 68 ? 2.346 15.866 33.689 1.00 41.22 ? 68 LYS A CB 1 ATOM 486 C CG . LYS A 1 68 ? 1.668 15.060 34.792 1.00 40.61 ? 68 LYS A CG 1 ATOM 487 C CD . LYS A 1 68 ? 2.689 14.462 35.703 1.00 41.42 ? 68 LYS A CD 1 ATOM 488 C CE . LYS A 1 68 ? 2.183 13.201 36.347 1.00 41.27 ? 68 LYS A CE 1 ATOM 489 N NZ . LYS A 1 68 ? 3.397 12.366 36.485 1.00 44.00 ? 68 LYS A NZ 1 ATOM 490 N N . GLY A 1 69 ? 2.839 18.510 31.997 1.00 41.68 ? 69 GLY A N 1 ATOM 491 C CA . GLY A 1 69 ? 3.524 19.146 30.874 1.00 41.72 ? 69 GLY A CA 1 ATOM 492 C C . GLY A 1 69 ? 4.298 20.386 31.296 1.00 42.10 ? 69 GLY A C 1 ATOM 493 O O . GLY A 1 69 ? 5.388 20.651 30.772 1.00 41.34 ? 69 GLY A O 1 ATOM 494 N N . LYS A 1 70 ? 3.710 21.158 32.222 1.00 42.73 ? 70 LYS A N 1 ATOM 495 C CA . LYS A 1 70 ? 4.391 22.302 32.833 1.00 43.25 ? 70 LYS A CA 1 ATOM 496 C C . LYS A 1 70 ? 5.732 21.754 33.285 1.00 43.17 ? 70 LYS A C 1 ATOM 497 O O . LYS A 1 70 ? 6.788 22.148 32.783 1.00 43.48 ? 70 LYS A O 1 ATOM 498 C CB . LYS A 1 70 ? 3.651 22.808 34.079 1.00 43.61 ? 70 LYS A CB 1 ATOM 499 C CG . LYS A 1 70 ? 2.193 23.254 33.891 1.00 44.69 ? 70 LYS A CG 1 ATOM 500 C CD . LYS A 1 70 ? 2.079 24.747 33.684 1.00 45.63 ? 70 LYS A CD 1 ATOM 501 C CE . LYS A 1 70 ? 0.676 25.158 33.313 1.00 44.15 ? 70 LYS A CE 1 ATOM 502 N NZ . LYS A 1 70 ? 0.709 26.501 32.662 1.00 45.40 ? 70 LYS A NZ 1 ATOM 503 N N . LYS A 1 71 ? 5.669 20.797 34.205 1.00 42.42 ? 71 LYS A N 1 ATOM 504 C CA . LYS A 1 71 ? 6.859 20.200 34.786 1.00 41.58 ? 71 LYS A CA 1 ATOM 505 C C . LYS A 1 71 ? 7.840 19.678 33.742 1.00 41.04 ? 71 LYS A C 1 ATOM 506 O O . LYS A 1 71 ? 9.008 20.049 33.782 1.00 41.48 ? 71 LYS A O 1 ATOM 507 C CB . LYS A 1 71 ? 6.461 19.158 35.825 1.00 41.28 ? 71 LYS A CB 1 ATOM 508 C CG . LYS A 1 71 ? 5.611 19.791 36.912 1.00 40.91 ? 71 LYS A CG 1 ATOM 509 C CD . LYS A 1 71 ? 4.955 18.810 37.860 1.00 41.54 ? 71 LYS A CD 1 ATOM 510 C CE . LYS A 1 71 ? 3.871 19.550 38.675 1.00 42.86 ? 71 LYS A CE 1 ATOM 511 N NZ . LYS A 1 71 ? 3.330 18.727 39.796 1.00 43.45 ? 71 LYS A NZ 1 ATOM 512 N N . TYR A 1 72 ? 7.364 18.888 32.780 1.00 40.38 ? 72 TYR A N 1 ATOM 513 C CA . TYR A 1 72 ? 8.240 18.358 31.731 1.00 39.48 ? 72 TYR A CA 1 ATOM 514 C C . TYR A 1 72 ? 8.969 19.501 31.049 1.00 39.06 ? 72 TYR A C 1 ATOM 515 O O . TYR A 1 72 ? 10.196 19.489 30.933 1.00 38.08 ? 72 TYR A O 1 ATOM 516 C CB . TYR A 1 72 ? 7.475 17.545 30.653 1.00 39.54 ? 72 TYR A CB 1 ATOM 517 C CG . TYR A 1 72 ? 6.747 16.285 31.094 1.00 37.97 ? 72 TYR A CG 1 ATOM 518 C CD1 . TYR A 1 72 ? 7.187 15.534 32.154 1.00 37.67 ? 72 TYR A CD1 1 ATOM 519 C CD2 . TYR A 1 72 ? 5.636 15.827 30.401 1.00 37.29 ? 72 TYR A CD2 1 ATOM 520 C CE1 . TYR A 1 72 ? 6.515 14.369 32.543 1.00 36.82 ? 72 TYR A CE1 1 ATOM 521 C CE2 . TYR A 1 72 ? 4.967 14.687 30.784 1.00 35.24 ? 72 TYR A CE2 1 ATOM 522 C CZ . TYR A 1 72 ? 5.421 13.953 31.856 1.00 34.84 ? 72 TYR A CZ 1 ATOM 523 O OH . TYR A 1 72 ? 4.793 12.797 32.253 1.00 32.61 ? 72 TYR A OH 1 ATOM 524 N N . SER A 1 73 ? 8.186 20.480 30.599 1.00 39.24 ? 73 SER A N 1 ATOM 525 C CA . SER A 1 73 ? 8.705 21.667 29.937 1.00 39.45 ? 73 SER A CA 1 ATOM 526 C C . SER A 1 73 ? 9.718 22.404 30.840 1.00 39.14 ? 73 SER A C 1 ATOM 527 O O . SER A 1 73 ? 10.843 22.717 30.413 1.00 38.55 ? 73 SER A O 1 ATOM 528 C CB . SER A 1 73 ? 7.550 22.577 29.527 1.00 39.77 ? 73 SER A CB 1 ATOM 529 O OG . SER A 1 73 ? 8.006 23.767 28.867 1.00 42.02 ? 73 SER A OG 1 ATOM 530 N N . ALA A 1 74 ? 9.326 22.645 32.087 1.00 38.84 ? 74 ALA A N 1 ATOM 531 C CA . ALA A 1 74 ? 10.226 23.231 33.086 1.00 39.25 ? 74 ALA A CA 1 ATOM 532 C C . ALA A 1 74 ? 11.509 22.431 33.251 1.00 39.28 ? 74 ALA A C 1 ATOM 533 O O . ALA A 1 74 ? 12.597 23.002 33.244 1.00 39.88 ? 74 ALA A O 1 ATOM 534 C CB . ALA A 1 74 ? 9.527 23.390 34.438 1.00 38.81 ? 74 ALA A CB 1 ATOM 535 N N . LEU A 1 75 ? 11.382 21.115 33.400 1.00 39.06 ? 75 LEU A N 1 ATOM 536 C CA . LEU A 1 75 ? 12.541 20.270 33.609 1.00 39.09 ? 75 LEU A CA 1 ATOM 537 C C . LEU A 1 75 ? 13.524 20.397 32.449 1.00 39.58 ? 75 LEU A C 1 ATOM 538 O O . LEU A 1 75 ? 14.729 20.553 32.665 1.00 39.49 ? 75 LEU A O 1 ATOM 539 C CB . LEU A 1 75 ? 12.132 18.805 33.858 1.00 38.54 ? 75 LEU A CB 1 ATOM 540 C CG . LEU A 1 75 ? 13.229 17.725 33.925 1.00 38.60 ? 75 LEU A CG 1 ATOM 541 C CD1 . LEU A 1 75 ? 14.290 18.074 34.965 1.00 37.92 ? 75 LEU A CD1 1 ATOM 542 C CD2 . LEU A 1 75 ? 12.695 16.339 34.215 1.00 37.87 ? 75 LEU A CD2 1 ATOM 543 N N . ILE A 1 76 ? 13.018 20.337 31.221 1.00 40.41 ? 76 ILE A N 1 ATOM 544 C CA . ILE A 1 76 ? 13.903 20.381 30.044 1.00 41.16 ? 76 ILE A CA 1 ATOM 545 C C . ILE A 1 76 ? 14.577 21.750 29.851 1.00 41.50 ? 76 ILE A C 1 ATOM 546 O O . ILE A 1 76 ? 15.667 21.820 29.294 1.00 41.37 ? 76 ILE A O 1 ATOM 547 C CB . ILE A 1 76 ? 13.212 19.891 28.750 1.00 40.75 ? 76 ILE A CB 1 ATOM 548 C CG1 . ILE A 1 76 ? 12.637 18.490 28.954 1.00 41.17 ? 76 ILE A CG1 1 ATOM 549 C CG2 . ILE A 1 76 ? 14.207 19.826 27.612 1.00 41.00 ? 76 ILE A CG2 1 ATOM 550 C CD1 . ILE A 1 76 ? 11.281 18.266 28.246 1.00 42.21 ? 76 ILE A CD1 1 ATOM 551 N N . GLU A 1 77 ? 13.946 22.823 30.324 1.00 41.97 ? 77 GLU A N 1 ATOM 552 C CA . GLU A 1 77 ? 14.595 24.132 30.298 1.00 43.43 ? 77 GLU A CA 1 ATOM 553 C C . GLU A 1 77 ? 15.810 24.114 31.243 1.00 43.78 ? 77 GLU A C 1 ATOM 554 O O . GLU A 1 77 ? 16.936 24.446 30.835 1.00 43.74 ? 77 GLU A O 1 ATOM 555 C CB . GLU A 1 77 ? 13.620 25.257 30.666 1.00 43.79 ? 77 GLU A CB 1 ATOM 556 C CG . GLU A 1 77 ? 12.463 25.421 29.659 1.00 46.44 ? 77 GLU A CG 1 ATOM 557 C CD . GLU A 1 77 ? 12.037 26.879 29.459 1.00 51.19 ? 77 GLU A CD 1 ATOM 558 O OE1 . GLU A 1 77 ? 11.729 27.571 30.467 1.00 52.01 ? 77 GLU A OE1 1 ATOM 559 O OE2 . GLU A 1 77 ? 12.023 27.339 28.283 1.00 52.31 ? 77 GLU A OE2 1 ATOM 560 N N . GLU A 1 78 ? 15.571 23.681 32.486 1.00 43.91 ? 78 GLU A N 1 ATOM 561 C CA . GLU A 1 78 ? 16.613 23.529 33.505 1.00 44.14 ? 78 GLU A CA 1 ATOM 562 C C . GLU A 1 78 ? 17.751 22.632 33.078 1.00 43.74 ? 78 GLU A C 1 ATOM 563 O O . GLU A 1 78 ? 18.911 22.911 33.379 1.00 43.43 ? 78 GLU A O 1 ATOM 564 C CB . GLU A 1 78 ? 16.021 23.003 34.809 1.00 44.36 ? 78 GLU A CB 1 ATOM 565 C CG . GLU A 1 78 ? 15.280 24.055 35.594 1.00 46.64 ? 78 GLU A CG 1 ATOM 566 C CD . GLU A 1 78 ? 14.756 23.567 36.939 1.00 50.58 ? 78 GLU A CD 1 ATOM 567 O OE1 . GLU A 1 78 ? 13.707 24.112 37.350 1.00 53.98 ? 78 GLU A OE1 1 ATOM 568 O OE2 . GLU A 1 78 ? 15.363 22.675 37.592 1.00 50.81 ? 78 GLU A OE2 1 ATOM 569 N N . ILE A 1 79 ? 17.421 21.556 32.378 1.00 43.50 ? 79 ILE A N 1 ATOM 570 C CA . ILE A 1 79 ? 18.452 20.710 31.811 1.00 43.78 ? 79 ILE A CA 1 ATOM 571 C C . ILE A 1 79 ? 19.288 21.499 30.780 1.00 44.28 ? 79 ILE A C 1 ATOM 572 O O . ILE A 1 79 ? 20.504 21.377 30.747 1.00 43.76 ? 79 ILE A O 1 ATOM 573 C CB . ILE A 1 79 ? 17.861 19.398 31.254 1.00 43.52 ? 79 ILE A CB 1 ATOM 574 C CG1 . ILE A 1 79 ? 17.377 18.546 32.415 1.00 42.27 ? 79 ILE A CG1 1 ATOM 575 C CG2 . ILE A 1 79 ? 18.891 18.625 30.444 1.00 42.79 ? 79 ILE A CG2 1 ATOM 576 C CD1 . ILE A 1 79 ? 16.457 17.464 32.003 1.00 41.00 ? 79 ILE A CD1 1 ATOM 577 N N . GLN A 1 80 ? 18.626 22.332 29.981 1.00 45.31 ? 80 GLN A N 1 ATOM 578 C CA . GLN A 1 80 ? 19.308 23.139 28.958 1.00 46.49 ? 80 GLN A CA 1 ATOM 579 C C . GLN A 1 80 ? 20.078 24.341 29.523 1.00 46.64 ? 80 GLN A C 1 ATOM 580 O O . GLN A 1 80 ? 21.083 24.751 28.956 1.00 46.11 ? 80 GLN A O 1 ATOM 581 C CB . GLN A 1 80 ? 18.315 23.583 27.881 1.00 46.56 ? 80 GLN A CB 1 ATOM 582 C CG . GLN A 1 80 ? 17.880 22.426 26.993 1.00 47.76 ? 80 GLN A CG 1 ATOM 583 C CD . GLN A 1 80 ? 16.699 22.744 26.076 1.00 49.01 ? 80 GLN A CD 1 ATOM 584 O OE1 . GLN A 1 80 ? 15.983 23.746 26.246 1.00 48.21 ? 80 GLN A OE1 1 ATOM 585 N NE2 . GLN A 1 80 ? 16.492 21.872 25.091 1.00 48.73 ? 80 GLN A NE2 1 ATOM 586 N N . GLN A 1 81 ? 19.602 24.894 30.637 1.00 47.34 ? 81 GLN A N 1 ATOM 587 C CA . GLN A 1 81 ? 20.295 25.998 31.290 1.00 48.09 ? 81 GLN A CA 1 ATOM 588 C C . GLN A 1 81 ? 21.579 25.579 31.995 1.00 47.95 ? 81 GLN A C 1 ATOM 589 O O . GLN A 1 81 ? 22.531 26.355 32.033 1.00 48.21 ? 81 GLN A O 1 ATOM 590 C CB . GLN A 1 81 ? 19.387 26.689 32.290 1.00 48.33 ? 81 GLN A CB 1 ATOM 591 C CG . GLN A 1 81 ? 18.567 27.812 31.710 1.00 50.95 ? 81 GLN A CG 1 ATOM 592 C CD . GLN A 1 81 ? 17.441 28.203 32.640 1.00 55.24 ? 81 GLN A CD 1 ATOM 593 O OE1 . GLN A 1 81 ? 17.578 28.136 33.866 1.00 56.03 ? 81 GLN A OE1 1 ATOM 594 N NE2 . GLN A 1 81 ? 16.306 28.610 32.066 1.00 57.09 ? 81 GLN A NE2 1 ATOM 595 N N . ASN A 1 82 ? 21.611 24.363 32.539 1.00 47.68 ? 82 ASN A N 1 ATOM 596 C CA . ASN A 1 82 ? 22.674 23.964 33.463 1.00 47.37 ? 82 ASN A CA 1 ATOM 597 C C . ASN A 1 82 ? 23.795 23.107 32.848 1.00 48.04 ? 82 ASN A C 1 ATOM 598 O O . ASN A 1 82 ? 24.961 23.270 33.205 1.00 48.30 ? 82 ASN A O 1 ATOM 599 C CB . ASN A 1 82 ? 22.107 23.240 34.704 1.00 47.05 ? 82 ASN A CB 1 ATOM 600 C CG . ASN A 1 82 ? 21.164 24.105 35.576 1.00 44.77 ? 82 ASN A CG 1 ATOM 601 O OD1 . ASN A 1 82 ? 20.853 25.260 35.276 1.00 42.67 ? 82 ASN A OD1 1 ATOM 602 N ND2 . ASN A 1 82 ? 20.712 23.494 36.683 1.00 43.65 ? 82 ASN A ND2 1 ATOM 603 N N . ALA A 1 83 ? 23.459 22.198 31.938 1.00 48.53 ? 83 ALA A N 1 ATOM 604 C CA . ALA A 1 83 ? 24.444 21.210 31.462 1.00 49.30 ? 83 ALA A CA 1 ATOM 605 C C . ALA A 1 83 ? 25.482 21.756 30.470 1.00 50.05 ? 83 ALA A C 1 ATOM 606 O O . ALA A 1 83 ? 25.200 22.668 29.695 1.00 49.78 ? 83 ALA A O 1 ATOM 607 C CB . ALA A 1 83 ? 23.746 19.992 30.876 1.00 48.91 ? 83 ALA A CB 1 ATOM 608 N N . THR A 1 84 ? 26.675 21.165 30.484 1.00 51.28 ? 84 THR A N 1 ATOM 609 C CA . THR A 1 84 ? 27.796 21.662 29.671 1.00 52.63 ? 84 THR A CA 1 ATOM 610 C C . THR A 1 84 ? 28.183 20.698 28.550 1.00 53.28 ? 84 THR A C 1 ATOM 611 O O . THR A 1 84 ? 28.896 21.075 27.622 1.00 53.77 ? 84 THR A O 1 ATOM 612 C CB . THR A 1 84 ? 29.049 21.973 30.532 1.00 52.73 ? 84 THR A CB 1 ATOM 613 O OG1 . THR A 1 84 ? 29.561 20.747 31.088 1.00 52.72 ? 84 THR A OG1 1 ATOM 614 C CG2 . THR A 1 84 ? 28.717 22.999 31.669 1.00 52.42 ? 84 THR A CG2 1 ATOM 615 N N . THR A 1 85 ? 27.738 19.449 28.648 1.00 53.98 ? 85 THR A N 1 ATOM 616 C CA . THR A 1 85 ? 27.933 18.486 27.555 1.00 54.66 ? 85 THR A CA 1 ATOM 617 C C . THR A 1 85 ? 26.656 17.724 27.159 1.00 54.43 ? 85 THR A C 1 ATOM 618 O O . THR A 1 85 ? 26.250 16.759 27.832 1.00 54.58 ? 85 THR A O 1 ATOM 619 C CB . THR A 1 85 ? 29.112 17.472 27.810 1.00 54.88 ? 85 THR A CB 1 ATOM 620 O OG1 . THR A 1 85 ? 28.976 16.857 29.102 1.00 55.48 ? 85 THR A OG1 1 ATOM 621 C CG2 . THR A 1 85 ? 30.484 18.161 27.686 1.00 55.44 ? 85 THR A CG2 1 ATOM 622 N N . PHE A 1 86 ? 26.036 18.154 26.065 1.00 53.83 ? 86 PHE A N 1 ATOM 623 C CA . PHE A 1 86 ? 25.020 17.338 25.421 1.00 53.60 ? 86 PHE A CA 1 ATOM 624 C C . PHE A 1 86 ? 25.661 16.653 24.234 1.00 53.18 ? 86 PHE A C 1 ATOM 625 O O . PHE A 1 86 ? 25.628 17.185 23.124 1.00 53.18 ? 86 PHE A O 1 ATOM 626 C CB . PHE A 1 86 ? 23.845 18.178 24.906 1.00 53.75 ? 86 PHE A CB 1 ATOM 627 C CG . PHE A 1 86 ? 23.322 19.189 25.886 1.00 53.60 ? 86 PHE A CG 1 ATOM 628 C CD1 . PHE A 1 86 ? 22.271 18.868 26.737 1.00 52.81 ? 86 PHE A CD1 1 ATOM 629 C CD2 . PHE A 1 86 ? 23.854 20.478 25.925 1.00 54.28 ? 86 PHE A CD2 1 ATOM 630 C CE1 . PHE A 1 86 ? 21.769 19.805 27.627 1.00 53.32 ? 86 PHE A CE1 1 ATOM 631 C CE2 . PHE A 1 86 ? 23.358 21.430 26.811 1.00 54.72 ? 86 PHE A CE2 1 ATOM 632 C CZ . PHE A 1 86 ? 22.302 21.094 27.664 1.00 54.24 ? 86 PHE A CZ 1 ATOM 633 N N . ASP A 1 87 ? 26.276 15.499 24.454 1.00 52.81 ? 87 ASP A N 1 ATOM 634 C CA . ASP A 1 87 ? 26.785 14.739 23.315 1.00 52.94 ? 87 ASP A CA 1 ATOM 635 C C . ASP A 1 87 ? 26.524 13.239 23.430 1.00 52.53 ? 87 ASP A C 1 ATOM 636 O O . ASP A 1 87 ? 25.938 12.781 24.420 1.00 52.87 ? 87 ASP A O 1 ATOM 637 C CB . ASP A 1 87 ? 28.246 15.098 22.976 1.00 53.42 ? 87 ASP A CB 1 ATOM 638 C CG . ASP A 1 87 ? 29.218 14.809 24.118 1.00 54.60 ? 87 ASP A CG 1 ATOM 639 O OD1 . ASP A 1 87 ? 29.246 13.650 24.599 1.00 54.80 ? 87 ASP A OD1 1 ATOM 640 O OD2 . ASP A 1 87 ? 29.969 15.740 24.514 1.00 55.84 ? 87 ASP A OD2 1 ATOM 641 N N . GLY A 1 88 ? 26.940 12.480 22.414 1.00 51.98 ? 88 GLY A N 1 ATOM 642 C CA . GLY A 1 88 ? 26.465 11.100 22.228 1.00 50.83 ? 88 GLY A CA 1 ATOM 643 C C . GLY A 1 88 ? 24.942 11.132 22.117 1.00 50.12 ? 88 GLY A C 1 ATOM 644 O O . GLY A 1 88 ? 24.372 12.026 21.462 1.00 49.74 ? 88 GLY A O 1 ATOM 645 N N . LYS A 1 89 ? 24.282 10.194 22.802 1.00 49.32 ? 89 LYS A N 1 ATOM 646 C CA . LYS A 1 89 ? 22.818 10.102 22.807 1.00 47.96 ? 89 LYS A CA 1 ATOM 647 C C . LYS A 1 89 ? 22.125 11.292 23.459 1.00 47.09 ? 89 LYS A C 1 ATOM 648 O O . LYS A 1 89 ? 20.908 11.389 23.436 1.00 47.05 ? 89 LYS A O 1 ATOM 649 C CB . LYS A 1 89 ? 22.364 8.786 23.451 1.00 48.48 ? 89 LYS A CB 1 ATOM 650 C CG . LYS A 1 89 ? 22.959 8.452 24.843 1.00 48.99 ? 89 LYS A CG 1 ATOM 651 C CD . LYS A 1 89 ? 22.927 6.926 25.058 1.00 51.14 ? 89 LYS A CD 1 ATOM 652 C CE . LYS A 1 89 ? 23.250 6.512 26.508 1.00 53.02 ? 89 LYS A CE 1 ATOM 653 N NZ . LYS A 1 89 ? 23.031 5.044 26.742 1.00 51.29 ? 89 LYS A NZ 1 ATOM 654 N N . TYR A 1 90 ? 22.901 12.211 24.019 1.00 46.03 ? 90 TYR A N 1 ATOM 655 C CA . TYR A 1 90 ? 22.334 13.367 24.703 1.00 45.04 ? 90 TYR A CA 1 ATOM 656 C C . TYR A 1 90 ? 22.166 14.585 23.817 1.00 44.81 ? 90 TYR A C 1 ATOM 657 O O . TYR A 1 90 ? 21.451 15.515 24.186 1.00 44.84 ? 90 TYR A O 1 ATOM 658 C CB . TYR A 1 90 ? 23.159 13.737 25.957 1.00 44.66 ? 90 TYR A CB 1 ATOM 659 C CG . TYR A 1 90 ? 23.111 12.683 27.023 1.00 42.75 ? 90 TYR A CG 1 ATOM 660 C CD1 . TYR A 1 90 ? 22.067 12.644 27.936 1.00 41.83 ? 90 TYR A CD1 1 ATOM 661 C CD2 . TYR A 1 90 ? 24.094 11.704 27.101 1.00 41.64 ? 90 TYR A CD2 1 ATOM 662 C CE1 . TYR A 1 90 ? 22.010 11.657 28.930 1.00 41.19 ? 90 TYR A CE1 1 ATOM 663 C CE2 . TYR A 1 90 ? 24.055 10.717 28.081 1.00 41.01 ? 90 TYR A CE2 1 ATOM 664 C CZ . TYR A 1 90 ? 23.005 10.695 28.998 1.00 41.00 ? 90 TYR A CZ 1 ATOM 665 O OH . TYR A 1 90 ? 22.956 9.715 29.972 1.00 39.02 ? 90 TYR A OH 1 ATOM 666 N N . ALA A 1 91 ? 22.809 14.579 22.656 1.00 44.80 ? 91 ALA A N 1 ATOM 667 C CA . ALA A 1 91 ? 22.891 15.780 21.812 1.00 45.06 ? 91 ALA A CA 1 ATOM 668 C C . ALA A 1 91 ? 21.549 16.490 21.603 1.00 45.06 ? 91 ALA A C 1 ATOM 669 O O . ALA A 1 91 ? 21.439 17.724 21.737 1.00 44.68 ? 91 ALA A O 1 ATOM 670 C CB . ALA A 1 91 ? 23.563 15.452 20.479 1.00 45.15 ? 91 ALA A CB 1 ATOM 671 N N . PHE A 1 92 ? 20.527 15.686 21.317 1.00 45.46 ? 92 PHE A N 1 ATOM 672 C CA . PHE A 1 92 ? 19.171 16.174 20.995 1.00 45.36 ? 92 PHE A CA 1 ATOM 673 C C . PHE A 1 92 ? 18.562 17.098 22.039 1.00 45.68 ? 92 PHE A C 1 ATOM 674 O O . PHE A 1 92 ? 17.729 17.966 21.720 1.00 45.37 ? 92 PHE A O 1 ATOM 675 C CB . PHE A 1 92 ? 18.228 14.985 20.747 1.00 45.59 ? 92 PHE A CB 1 ATOM 676 C CG . PHE A 1 92 ? 17.759 14.289 21.998 1.00 43.87 ? 92 PHE A CG 1 ATOM 677 C CD1 . PHE A 1 92 ? 18.444 13.188 22.493 1.00 42.95 ? 92 PHE A CD1 1 ATOM 678 C CD2 . PHE A 1 92 ? 16.602 14.711 22.650 1.00 43.58 ? 92 PHE A CD2 1 ATOM 679 C CE1 . PHE A 1 92 ? 17.994 12.524 23.642 1.00 42.61 ? 92 PHE A CE1 1 ATOM 680 C CE2 . PHE A 1 92 ? 16.151 14.067 23.800 1.00 43.07 ? 92 PHE A CE2 1 ATOM 681 C CZ . PHE A 1 92 ? 16.854 12.961 24.295 1.00 42.77 ? 92 PHE A CZ 1 ATOM 682 N N . LEU A 1 93 ? 18.969 16.897 23.291 1.00 46.01 ? 93 LEU A N 1 ATOM 683 C CA . LEU A 1 93 ? 18.433 17.681 24.389 1.00 46.52 ? 93 LEU A CA 1 ATOM 684 C C . LEU A 1 93 ? 18.850 19.128 24.331 1.00 47.18 ? 93 LEU A C 1 ATOM 685 O O . LEU A 1 93 ? 18.159 19.974 24.898 1.00 46.69 ? 93 LEU A O 1 ATOM 686 C CB . LEU A 1 93 ? 18.850 17.095 25.724 1.00 46.27 ? 93 LEU A CB 1 ATOM 687 C CG . LEU A 1 93 ? 17.928 16.042 26.305 1.00 45.74 ? 93 LEU A CG 1 ATOM 688 C CD1 . LEU A 1 93 ? 18.653 15.421 27.479 1.00 45.39 ? 93 LEU A CD1 1 ATOM 689 C CD2 . LEU A 1 93 ? 16.628 16.689 26.726 1.00 42.53 ? 93 LEU A CD2 1 ATOM 690 N N . LYS A 1 94 ? 19.977 19.410 23.662 1.00 48.34 ? 94 LYS A N 1 ATOM 691 C CA . LYS A 1 94 ? 20.481 20.781 23.594 1.00 49.62 ? 94 LYS A CA 1 ATOM 692 C C . LYS A 1 94 ? 19.390 21.711 23.061 1.00 50.06 ? 94 LYS A C 1 ATOM 693 O O . LYS A 1 94 ? 19.062 22.734 23.694 1.00 50.22 ? 94 LYS A O 1 ATOM 694 C CB . LYS A 1 94 ? 21.782 20.902 22.779 1.00 49.86 ? 94 LYS A CB 1 ATOM 695 C CG . LYS A 1 94 ? 22.337 22.341 22.795 1.00 51.46 ? 94 LYS A CG 1 ATOM 696 C CD . LYS A 1 94 ? 23.854 22.449 22.515 1.00 54.55 ? 94 LYS A CD 1 ATOM 697 C CE . LYS A 1 94 ? 24.265 23.940 22.381 1.00 55.51 ? 94 LYS A CE 1 ATOM 698 N NZ . LYS A 1 94 ? 25.670 24.235 22.819 1.00 56.86 ? 94 LYS A NZ 1 ATOM 699 N N . THR A 1 95 ? 18.803 21.311 21.931 1.00 50.37 ? 95 THR A N 1 ATOM 700 C CA . THR A 1 95 ? 17.861 22.148 21.178 1.00 50.69 ? 95 THR A CA 1 ATOM 701 C C . THR A 1 95 ? 16.399 21.765 21.369 1.00 50.43 ? 95 THR A C 1 ATOM 702 O O . THR A 1 95 ? 15.499 22.549 21.012 1.00 50.89 ? 95 THR A O 1 ATOM 703 C CB . THR A 1 95 ? 18.148 22.113 19.643 1.00 51.25 ? 95 THR A CB 1 ATOM 704 O OG1 . THR A 1 95 ? 18.428 20.759 19.218 1.00 51.42 ? 95 THR A OG1 1 ATOM 705 C CG2 . THR A 1 95 ? 19.308 23.055 19.279 1.00 50.78 ? 95 THR A CG2 1 ATOM 706 N N . TYR A 1 96 ? 16.155 20.572 21.914 1.00 49.54 ? 96 TYR A N 1 ATOM 707 C CA . TYR A 1 96 ? 14.783 20.087 22.053 1.00 48.42 ? 96 TYR A CA 1 ATOM 708 C C . TYR A 1 96 ? 13.802 21.185 22.481 1.00 48.28 ? 96 TYR A C 1 ATOM 709 O O . TYR A 1 96 ? 14.029 21.890 23.466 1.00 47.88 ? 96 TYR A O 1 ATOM 710 C CB . TYR A 1 96 ? 14.679 18.882 22.987 1.00 48.07 ? 96 TYR A CB 1 ATOM 711 C CG . TYR A 1 96 ? 13.288 18.301 22.980 1.00 45.91 ? 96 TYR A CG 1 ATOM 712 C CD1 . TYR A 1 96 ? 12.942 17.320 22.072 1.00 44.41 ? 96 TYR A CD1 1 ATOM 713 C CD2 . TYR A 1 96 ? 12.304 18.769 23.853 1.00 44.45 ? 96 TYR A CD2 1 ATOM 714 C CE1 . TYR A 1 96 ? 11.668 16.796 22.050 1.00 43.19 ? 96 TYR A CE1 1 ATOM 715 C CE2 . TYR A 1 96 ? 11.033 18.256 23.834 1.00 42.91 ? 96 TYR A CE2 1 ATOM 716 C CZ . TYR A 1 96 ? 10.721 17.272 22.932 1.00 42.95 ? 96 TYR A CZ 1 ATOM 717 O OH . TYR A 1 96 ? 9.453 16.740 22.908 1.00 43.93 ? 96 TYR A OH 1 ATOM 718 N N . ASN A 1 97 ? 12.719 21.302 21.708 1.00 48.26 ? 97 ASN A N 1 ATOM 719 C CA . ASN A 1 97 ? 11.785 22.431 21.772 1.00 48.08 ? 97 ASN A CA 1 ATOM 720 C C . ASN A 1 97 ? 10.373 21.938 22.046 1.00 47.29 ? 97 ASN A C 1 ATOM 721 O O . ASN A 1 97 ? 9.600 21.666 21.124 1.00 47.68 ? 97 ASN A O 1 ATOM 722 C CB . ASN A 1 97 ? 11.833 23.242 20.457 1.00 48.63 ? 97 ASN A CB 1 ATOM 723 C CG . ASN A 1 97 ? 11.032 24.544 20.521 1.00 49.29 ? 97 ASN A CG 1 ATOM 724 O OD1 . ASN A 1 97 ? 10.526 24.949 21.574 1.00 49.69 ? 97 ASN A OD1 1 ATOM 725 N ND2 . ASN A 1 97 ? 10.918 25.204 19.381 1.00 50.96 ? 97 ASN A ND2 1 ATOM 726 N N . TYR A 1 98 ? 10.055 21.832 23.329 1.00 46.20 ? 98 TYR A N 1 ATOM 727 C CA . TYR A 1 98 ? 8.816 21.222 23.797 1.00 45.04 ? 98 TYR A CA 1 ATOM 728 C C . TYR A 1 98 ? 7.593 21.945 23.224 1.00 44.69 ? 98 TYR A C 1 ATOM 729 O O . TYR A 1 98 ? 7.370 23.137 23.493 1.00 44.60 ? 98 TYR A O 1 ATOM 730 C CB . TYR A 1 98 ? 8.790 21.190 25.325 1.00 44.04 ? 98 TYR A CB 1 ATOM 731 C CG . TYR A 1 98 ? 7.641 20.432 25.936 1.00 42.89 ? 98 TYR A CG 1 ATOM 732 C CD1 . TYR A 1 98 ? 6.401 21.058 26.162 1.00 43.30 ? 98 TYR A CD1 1 ATOM 733 C CD2 . TYR A 1 98 ? 7.789 19.110 26.344 1.00 40.30 ? 98 TYR A CD2 1 ATOM 734 C CE1 . TYR A 1 98 ? 5.341 20.378 26.756 1.00 40.88 ? 98 TYR A CE1 1 ATOM 735 C CE2 . TYR A 1 98 ? 6.736 18.426 26.947 1.00 38.31 ? 98 TYR A CE2 1 ATOM 736 C CZ . TYR A 1 98 ? 5.514 19.059 27.139 1.00 39.08 ? 98 TYR A CZ 1 ATOM 737 O OH . TYR A 1 98 ? 4.457 18.395 27.722 1.00 38.22 ? 98 TYR A OH 1 ATOM 738 N N . SER A 1 99 ? 6.821 21.206 22.425 1.00 44.02 ? 99 SER A N 1 ATOM 739 C CA . SER A 1 99 ? 5.638 21.742 21.752 1.00 43.41 ? 99 SER A CA 1 ATOM 740 C C . SER A 1 99 ? 4.340 20.964 21.981 1.00 43.23 ? 99 SER A C 1 ATOM 741 O O . SER A 1 99 ? 3.263 21.484 21.651 1.00 43.70 ? 99 SER A O 1 ATOM 742 C CB . SER A 1 99 ? 5.889 21.912 20.260 1.00 43.12 ? 99 SER A CB 1 ATOM 743 O OG . SER A 1 99 ? 6.960 21.098 19.827 1.00 43.33 ? 99 SER A OG 1 ATOM 744 N N . LEU A 1 100 ? 4.435 19.752 22.553 1.00 41.81 ? 100 LEU A N 1 ATOM 745 C CA . LEU A 1 100 ? 3.262 18.912 22.887 1.00 40.39 ? 100 LEU A CA 1 ATOM 746 C C . LEU A 1 100 ? 1.994 19.647 23.380 1.00 39.78 ? 100 LEU A C 1 ATOM 747 O O . LEU A 1 100 ? 2.076 20.655 24.090 1.00 39.66 ? 100 LEU A O 1 ATOM 748 C CB . LEU A 1 100 ? 3.631 17.885 23.947 1.00 40.04 ? 100 LEU A CB 1 ATOM 749 C CG . LEU A 1 100 ? 4.860 17.008 23.769 1.00 39.80 ? 100 LEU A CG 1 ATOM 750 C CD1 . LEU A 1 100 ? 4.901 15.948 24.874 1.00 38.17 ? 100 LEU A CD1 1 ATOM 751 C CD2 . LEU A 1 100 ? 4.867 16.381 22.385 1.00 40.89 ? 100 LEU A CD2 1 ATOM 752 N N . GLY A 1 101 ? 0.827 19.103 23.025 1.00 38.46 ? 101 GLY A N 1 ATOM 753 C CA . GLY A 1 101 ? -0.443 19.635 23.456 1.00 37.35 ? 101 GLY A CA 1 ATOM 754 C C . GLY A 1 101 ? -0.732 19.237 24.883 1.00 36.79 ? 101 GLY A C 1 ATOM 755 O O . GLY A 1 101 ? 0.149 18.734 25.576 1.00 36.47 ? 101 GLY A O 1 ATOM 756 N N . ALA A 1 102 ? -1.977 19.424 25.317 1.00 36.09 ? 102 ALA A N 1 ATOM 757 C CA . ALA A 1 102 ? -2.333 19.208 26.714 1.00 36.12 ? 102 ALA A CA 1 ATOM 758 C C . ALA A 1 102 ? -3.756 18.716 26.953 1.00 36.12 ? 102 ALA A C 1 ATOM 759 O O . ALA A 1 102 ? -4.741 19.356 26.550 1.00 36.50 ? 102 ALA A O 1 ATOM 760 C CB . ALA A 1 102 ? -2.096 20.490 27.526 1.00 36.45 ? 102 ALA A CB 1 ATOM 761 N N . ASP A 1 103 ? -3.842 17.603 27.675 1.00 35.86 ? 103 ASP A N 1 ATOM 762 C CA . ASP A 1 103 ? -5.105 16.923 28.029 1.00 35.77 ? 103 ASP A CA 1 ATOM 763 C C . ASP A 1 103 ? -5.797 16.215 26.853 1.00 35.19 ? 103 ASP A C 1 ATOM 764 O O . ASP A 1 103 ? -6.389 15.146 27.036 1.00 35.65 ? 103 ASP A O 1 ATOM 765 C CB . ASP A 1 103 ? -6.093 17.880 28.718 1.00 36.31 ? 103 ASP A CB 1 ATOM 766 C CG . ASP A 1 103 ? -5.519 18.508 29.963 1.00 38.11 ? 103 ASP A CG 1 ATOM 767 O OD1 . ASP A 1 103 ? -5.462 17.801 30.999 1.00 38.18 ? 103 ASP A OD1 1 ATOM 768 O OD2 . ASP A 1 103 ? -5.127 19.699 29.892 1.00 38.07 ? 103 ASP A OD2 1 ATOM 769 N N . ASP A 1 104 ? -5.703 16.805 25.660 1.00 34.39 ? 104 ASP A N 1 ATOM 770 C CA . ASP A 1 104 ? -6.529 16.430 24.526 1.00 33.50 ? 104 ASP A CA 1 ATOM 771 C C . ASP A 1 104 ? -6.070 15.073 24.003 1.00 32.11 ? 104 ASP A C 1 ATOM 772 O O . ASP A 1 104 ? -4.988 14.620 24.327 1.00 31.94 ? 104 ASP A O 1 ATOM 773 C CB . ASP A 1 104 ? -6.510 17.532 23.432 1.00 34.31 ? 104 ASP A CB 1 ATOM 774 C CG . ASP A 1 104 ? -7.182 18.883 23.889 1.00 36.14 ? 104 ASP A CG 1 ATOM 775 O OD1 . ASP A 1 104 ? -7.839 18.935 24.958 1.00 38.34 ? 104 ASP A OD1 1 ATOM 776 O OD2 . ASP A 1 104 ? -7.057 19.903 23.162 1.00 36.35 ? 104 ASP A OD2 1 ATOM 777 N N . LEU A 1 105 ? -6.940 14.390 23.273 1.00 30.33 ? 105 LEU A N 1 ATOM 778 C CA . LEU A 1 105 ? -6.574 13.215 22.502 1.00 29.17 ? 105 LEU A CA 1 ATOM 779 C C . LEU A 1 105 ? -5.549 13.654 21.422 1.00 28.61 ? 105 LEU A C 1 ATOM 780 O O . LEU A 1 105 ? -5.603 14.792 20.943 1.00 29.51 ? 105 LEU A O 1 ATOM 781 C CB . LEU A 1 105 ? -7.865 12.723 21.836 1.00 29.06 ? 105 LEU A CB 1 ATOM 782 C CG . LEU A 1 105 ? -8.505 11.357 21.953 1.00 27.77 ? 105 LEU A CG 1 ATOM 783 C CD1 . LEU A 1 105 ? -8.414 10.897 23.356 1.00 28.12 ? 105 LEU A CD1 1 ATOM 784 C CD2 . LEU A 1 105 ? -9.966 11.424 21.501 1.00 26.86 ? 105 LEU A CD2 1 ATOM 785 N N . THR A 1 106 ? -4.616 12.794 21.040 1.00 27.55 ? 106 THR A N 1 ATOM 786 C CA . THR A 1 106 ? -3.705 13.112 19.917 1.00 27.03 ? 106 THR A CA 1 ATOM 787 C C . THR A 1 106 ? -4.208 12.523 18.574 1.00 27.37 ? 106 THR A C 1 ATOM 788 O O . THR A 1 106 ? -5.071 11.640 18.575 1.00 27.28 ? 106 THR A O 1 ATOM 789 C CB . THR A 1 106 ? -2.356 12.535 20.156 1.00 26.68 ? 106 THR A CB 1 ATOM 790 O OG1 . THR A 1 106 ? -2.457 11.097 20.103 1.00 27.29 ? 106 THR A OG1 1 ATOM 791 C CG2 . THR A 1 106 ? -1.809 13.009 21.510 1.00 25.47 ? 106 THR A CG2 1 ATOM 792 N N . PRO A 1 107 ? -3.684 13.006 17.421 1.00 27.61 ? 107 PRO A N 1 ATOM 793 C CA . PRO A 1 107 ? -4.210 12.404 16.186 1.00 27.13 ? 107 PRO A CA 1 ATOM 794 C C . PRO A 1 107 ? -4.154 10.899 16.280 1.00 26.47 ? 107 PRO A C 1 ATOM 795 O O . PRO A 1 107 ? -5.168 10.237 16.020 1.00 26.78 ? 107 PRO A O 1 ATOM 796 C CB . PRO A 1 107 ? -3.248 12.920 15.104 1.00 27.72 ? 107 PRO A CB 1 ATOM 797 C CG . PRO A 1 107 ? -2.861 14.306 15.609 1.00 28.29 ? 107 PRO A CG 1 ATOM 798 C CD . PRO A 1 107 ? -3.021 14.299 17.140 1.00 27.66 ? 107 PRO A CD 1 ATOM 799 N N . PHE A 1 108 ? -2.985 10.383 16.656 1.00 24.70 ? 108 PHE A N 1 ATOM 800 C CA . PHE A 1 108 ? -2.791 8.954 16.902 1.00 23.50 ? 108 PHE A CA 1 ATOM 801 C C . PHE A 1 108 ? -3.842 8.349 17.861 1.00 22.44 ? 108 PHE A C 1 ATOM 802 O O . PHE A 1 108 ? -4.472 7.351 17.552 1.00 21.78 ? 108 PHE A O 1 ATOM 803 C CB . PHE A 1 108 ? -1.377 8.713 17.450 1.00 23.19 ? 108 PHE A CB 1 ATOM 804 C CG . PHE A 1 108 ? -1.087 7.290 17.740 1.00 22.84 ? 108 PHE A CG 1 ATOM 805 C CD1 . PHE A 1 108 ? -0.792 6.408 16.722 1.00 21.63 ? 108 PHE A CD1 1 ATOM 806 C CD2 . PHE A 1 108 ? -1.120 6.819 19.044 1.00 24.24 ? 108 PHE A CD2 1 ATOM 807 C CE1 . PHE A 1 108 ? -0.538 5.081 16.990 1.00 22.75 ? 108 PHE A CE1 1 ATOM 808 C CE2 . PHE A 1 108 ? -0.878 5.483 19.325 1.00 25.42 ? 108 PHE A CE2 1 ATOM 809 C CZ . PHE A 1 108 ? -0.589 4.615 18.292 1.00 24.95 ? 108 PHE A CZ 1 ATOM 810 N N . GLY A 1 109 ? -4.005 8.946 19.037 1.00 22.10 ? 109 GLY A N 1 ATOM 811 C CA . GLY A 1 109 ? -5.050 8.517 19.960 1.00 21.77 ? 109 GLY A CA 1 ATOM 812 C C . GLY A 1 109 ? -6.431 8.446 19.332 1.00 20.74 ? 109 GLY A C 1 ATOM 813 O O . GLY A 1 109 ? -7.215 7.604 19.659 1.00 22.22 ? 109 GLY A O 1 ATOM 814 N N . GLU A 1 110 ? -6.718 9.354 18.430 1.00 20.55 ? 110 GLU A N 1 ATOM 815 C CA . GLU A 1 110 ? -7.991 9.433 17.730 1.00 19.90 ? 110 GLU A CA 1 ATOM 816 C C . GLU A 1 110 ? -8.133 8.216 16.837 1.00 18.77 ? 110 GLU A C 1 ATOM 817 O O . GLU A 1 110 ? -9.134 7.494 16.932 1.00 17.82 ? 110 GLU A O 1 ATOM 818 C CB . GLU A 1 110 ? -8.045 10.743 16.929 1.00 19.55 ? 110 GLU A CB 1 ATOM 819 C CG . GLU A 1 110 ? -8.240 11.972 17.826 1.00 22.93 ? 110 GLU A CG 1 ATOM 820 C CD . GLU A 1 110 ? -8.323 13.283 17.055 1.00 24.49 ? 110 GLU A CD 1 ATOM 821 O OE1 . GLU A 1 110 ? -8.399 13.245 15.827 1.00 26.57 ? 110 GLU A OE1 1 ATOM 822 O OE2 . GLU A 1 110 ? -8.285 14.364 17.661 1.00 27.55 ? 110 GLU A OE2 1 ATOM 823 N N . GLN A 1 111 ? -7.107 7.972 16.014 1.00 17.96 ? 111 GLN A N 1 ATOM 824 C CA . GLN A 1 111 ? -7.093 6.855 15.101 1.00 18.54 ? 111 GLN A CA 1 ATOM 825 C C . GLN A 1 111 ? -7.211 5.501 15.812 1.00 19.11 ? 111 GLN A C 1 ATOM 826 O O . GLN A 1 111 ? -7.839 4.590 15.283 1.00 19.13 ? 111 GLN A O 1 ATOM 827 C CB . GLN A 1 111 ? -5.844 6.871 14.213 1.00 19.05 ? 111 GLN A CB 1 ATOM 828 C CG . GLN A 1 111 ? -5.859 5.731 13.153 1.00 19.14 ? 111 GLN A CG 1 ATOM 829 C CD . GLN A 1 111 ? -6.965 5.981 12.129 1.00 21.03 ? 111 GLN A CD 1 ATOM 830 O OE1 . GLN A 1 111 ? -7.077 7.093 11.654 1.00 22.02 ? 111 GLN A OE1 1 ATOM 831 N NE2 . GLN A 1 111 ? -7.800 4.971 11.825 1.00 18.79 ? 111 GLN A NE2 1 ATOM 832 N N . GLU A 1 112 ? -6.593 5.377 16.989 1.00 19.38 ? 112 GLU A N 1 ATOM 833 C CA . GLU A 1 112 ? -6.738 4.180 17.835 1.00 20.84 ? 112 GLU A CA 1 ATOM 834 C C . GLU A 1 112 ? -8.208 3.836 18.090 1.00 20.81 ? 112 GLU A C 1 ATOM 835 O O . GLU A 1 112 ? -8.583 2.658 18.094 1.00 20.61 ? 112 GLU A O 1 ATOM 836 C CB . GLU A 1 112 ? -6.043 4.337 19.212 1.00 20.51 ? 112 GLU A CB 1 ATOM 837 C CG . GLU A 1 112 ? -4.561 3.893 19.274 1.00 22.27 ? 112 GLU A CG 1 ATOM 838 C CD . GLU A 1 112 ? -3.923 4.120 20.656 1.00 23.93 ? 112 GLU A CD 1 ATOM 839 O OE1 . GLU A 1 112 ? -4.288 5.093 21.327 1.00 25.78 ? 112 GLU A OE1 1 ATOM 840 O OE2 . GLU A 1 112 ? -3.074 3.321 21.092 1.00 22.87 ? 112 GLU A OE2 1 ATOM 841 N N . LEU A 1 113 ? -9.033 4.846 18.338 1.00 20.72 ? 113 LEU A N 1 ATOM 842 C CA . LEU A 1 113 ? -10.398 4.510 18.738 1.00 21.10 ? 113 LEU A CA 1 ATOM 843 C C . LEU A 1 113 ? -11.242 4.250 17.495 1.00 21.12 ? 113 LEU A C 1 ATOM 844 O O . LEU A 1 113 ? -12.240 3.535 17.584 1.00 21.16 ? 113 LEU A O 1 ATOM 845 C CB . LEU A 1 113 ? -11.007 5.585 19.645 1.00 20.78 ? 113 LEU A CB 1 ATOM 846 C CG . LEU A 1 113 ? -10.781 5.467 21.159 1.00 21.67 ? 113 LEU A CG 1 ATOM 847 C CD1 . LEU A 1 113 ? -11.896 4.673 21.870 1.00 21.85 ? 113 LEU A CD1 1 ATOM 848 C CD2 . LEU A 1 113 ? -9.412 4.931 21.502 1.00 20.34 ? 113 LEU A CD2 1 ATOM 849 N N . VAL A 1 114 ? -10.804 4.811 16.354 1.00 20.67 ? 114 VAL A N 1 ATOM 850 C CA . VAL A 1 114 ? -11.422 4.571 15.050 1.00 19.39 ? 114 VAL A CA 1 ATOM 851 C C . VAL A 1 114 ? -11.180 3.100 14.779 1.00 19.59 ? 114 VAL A C 1 ATOM 852 O O . VAL A 1 114 ? -12.140 2.340 14.535 1.00 19.21 ? 114 VAL A O 1 ATOM 853 C CB . VAL A 1 114 ? -10.802 5.453 13.925 1.00 19.73 ? 114 VAL A CB 1 ATOM 854 C CG1 . VAL A 1 114 ? -11.170 4.940 12.485 1.00 18.47 ? 114 VAL A CG1 1 ATOM 855 C CG2 . VAL A 1 114 ? -11.211 6.880 14.108 1.00 18.00 ? 114 VAL A CG2 1 ATOM 856 N N . ASN A 1 115 ? -9.909 2.706 14.896 1.00 18.40 ? 115 ASN A N 1 ATOM 857 C CA . ASN A 1 115 ? -9.486 1.317 14.718 1.00 18.08 ? 115 ASN A CA 1 ATOM 858 C C . ASN A 1 115 ? -10.175 0.288 15.653 1.00 17.18 ? 115 ASN A C 1 ATOM 859 O O . ASN A 1 115 ? -10.520 -0.809 15.236 1.00 17.40 ? 115 ASN A O 1 ATOM 860 C CB . ASN A 1 115 ? -7.968 1.222 14.837 1.00 17.35 ? 115 ASN A CB 1 ATOM 861 C CG . ASN A 1 115 ? -7.265 1.884 13.689 1.00 19.09 ? 115 ASN A CG 1 ATOM 862 O OD1 . ASN A 1 115 ? -7.918 2.452 12.791 1.00 18.73 ? 115 ASN A OD1 1 ATOM 863 N ND2 . ASN A 1 115 ? -5.912 1.803 13.677 1.00 15.18 ? 115 ASN A ND2 1 ATOM 864 N N . SER A 1 116 ? -10.333 0.647 16.918 1.00 16.88 ? 116 SER A N 1 ATOM 865 C CA . SER A 1 116 ? -11.100 -0.145 17.872 1.00 16.54 ? 116 SER A CA 1 ATOM 866 C C . SER A 1 116 ? -12.571 -0.319 17.404 1.00 15.98 ? 116 SER A C 1 ATOM 867 O O . SER A 1 116 ? -13.147 -1.383 17.581 1.00 15.37 ? 116 SER A O 1 ATOM 868 C CB . SER A 1 116 ? -11.042 0.522 19.255 1.00 16.48 ? 116 SER A CB 1 ATOM 869 O OG . SER A 1 116 ? -11.804 -0.189 20.253 1.00 17.27 ? 116 SER A OG 1 ATOM 870 N N . GLY A 1 117 ? -13.140 0.732 16.798 1.00 16.08 ? 117 GLY A N 1 ATOM 871 C CA . GLY A 1 117 ? -14.494 0.710 16.236 1.00 15.25 ? 117 GLY A CA 1 ATOM 872 C C . GLY A 1 117 ? -14.605 -0.211 15.024 1.00 15.02 ? 117 GLY A C 1 ATOM 873 O O . GLY A 1 117 ? -15.529 -1.007 14.921 1.00 14.31 ? 117 GLY A O 1 ATOM 874 N N . ILE A 1 118 ? -13.647 -0.116 14.109 1.00 14.57 ? 118 ILE A N 1 ATOM 875 C CA . ILE A 1 118 ? -13.644 -1.037 12.993 1.00 14.49 ? 118 ILE A CA 1 ATOM 876 C C . ILE A 1 118 ? -13.562 -2.470 13.563 1.00 15.14 ? 118 ILE A C 1 ATOM 877 O O . ILE A 1 118 ? -14.396 -3.356 13.263 1.00 13.88 ? 118 ILE A O 1 ATOM 878 C CB . ILE A 1 118 ? -12.475 -0.749 12.048 1.00 13.84 ? 118 ILE A CB 1 ATOM 879 C CG1 . ILE A 1 118 ? -12.630 0.646 11.501 1.00 13.09 ? 118 ILE A CG1 1 ATOM 880 C CG2 . ILE A 1 118 ? -12.470 -1.787 10.889 1.00 13.87 ? 118 ILE A CG2 1 ATOM 881 C CD1 . ILE A 1 118 ? -11.472 1.163 10.770 1.00 9.34 ? 118 ILE A CD1 1 ATOM 882 N N . LYS A 1 119 ? -12.572 -2.674 14.437 1.00 15.23 ? 119 LYS A N 1 ATOM 883 C CA . LYS A 1 119 ? -12.323 -4.025 14.976 1.00 15.47 ? 119 LYS A CA 1 ATOM 884 C C . LYS A 1 119 ? -13.567 -4.601 15.632 1.00 15.38 ? 119 LYS A C 1 ATOM 885 O O . LYS A 1 119 ? -13.910 -5.755 15.371 1.00 15.37 ? 119 LYS A O 1 ATOM 886 C CB . LYS A 1 119 ? -11.059 -4.063 15.878 1.00 14.96 ? 119 LYS A CB 1 ATOM 887 C CG . LYS A 1 119 ? -10.707 -5.453 16.356 1.00 15.80 ? 119 LYS A CG 1 ATOM 888 C CD . LYS A 1 119 ? -9.243 -5.679 16.523 1.00 16.95 ? 119 LYS A CD 1 ATOM 889 C CE . LYS A 1 119 ? -9.051 -7.078 17.000 1.00 16.94 ? 119 LYS A CE 1 ATOM 890 N NZ . LYS A 1 119 ? -7.728 -7.216 17.651 1.00 16.31 ? 119 LYS A NZ 1 ATOM 891 N N . PHE A 1 120 ? -14.256 -3.784 16.439 1.00 15.54 ? 120 PHE A N 1 ATOM 892 C CA . PHE A 1 120 ? -15.482 -4.269 17.143 1.00 16.41 ? 120 PHE A CA 1 ATOM 893 C C . PHE A 1 120 ? -16.603 -4.601 16.137 1.00 16.65 ? 120 PHE A C 1 ATOM 894 O O . PHE A 1 120 ? -17.335 -5.587 16.299 1.00 15.28 ? 120 PHE A O 1 ATOM 895 C CB . PHE A 1 120 ? -15.995 -3.251 18.196 1.00 14.91 ? 120 PHE A CB 1 ATOM 896 C CG . PHE A 1 120 ? -17.139 -3.756 19.035 1.00 14.57 ? 120 PHE A CG 1 ATOM 897 C CD1 . PHE A 1 120 ? -16.930 -4.687 20.061 1.00 16.08 ? 120 PHE A CD1 1 ATOM 898 C CD2 . PHE A 1 120 ? -18.403 -3.271 18.864 1.00 14.77 ? 120 PHE A CD2 1 ATOM 899 C CE1 . PHE A 1 120 ? -17.998 -5.150 20.890 1.00 13.86 ? 120 PHE A CE1 1 ATOM 900 C CE2 . PHE A 1 120 ? -19.479 -3.715 19.674 1.00 16.34 ? 120 PHE A CE2 1 ATOM 901 C CZ . PHE A 1 120 ? -19.253 -4.662 20.687 1.00 16.16 ? 120 PHE A CZ 1 ATOM 902 N N . TYR A 1 121 ? -16.723 -3.749 15.107 1.00 17.11 ? 121 TYR A N 1 ATOM 903 C CA . TYR A 1 121 ? -17.746 -3.961 14.113 1.00 17.96 ? 121 TYR A CA 1 ATOM 904 C C . TYR A 1 121 ? -17.623 -5.356 13.535 1.00 18.59 ? 121 TYR A C 1 ATOM 905 O O . TYR A 1 121 ? -18.597 -6.082 13.509 1.00 19.19 ? 121 TYR A O 1 ATOM 906 C CB . TYR A 1 121 ? -17.745 -2.929 12.967 1.00 17.77 ? 121 TYR A CB 1 ATOM 907 C CG . TYR A 1 121 ? -18.899 -3.238 12.019 1.00 18.15 ? 121 TYR A CG 1 ATOM 908 C CD1 . TYR A 1 121 ? -18.712 -3.980 10.844 1.00 16.60 ? 121 TYR A CD1 1 ATOM 909 C CD2 . TYR A 1 121 ? -20.204 -2.841 12.351 1.00 16.84 ? 121 TYR A CD2 1 ATOM 910 C CE1 . TYR A 1 121 ? -19.795 -4.270 9.988 1.00 13.64 ? 121 TYR A CE1 1 ATOM 911 C CE2 . TYR A 1 121 ? -21.264 -3.158 11.547 1.00 15.82 ? 121 TYR A CE2 1 ATOM 912 C CZ . TYR A 1 121 ? -21.065 -3.873 10.387 1.00 14.18 ? 121 TYR A CZ 1 ATOM 913 O OH . TYR A 1 121 ? -22.151 -4.120 9.643 1.00 15.03 ? 121 TYR A OH 1 ATOM 914 N N . GLN A 1 122 ? -16.405 -5.701 13.124 1.00 18.32 ? 122 GLN A N 1 ATOM 915 C CA . GLN A 1 122 ? -16.090 -6.903 12.408 1.00 19.69 ? 122 GLN A CA 1 ATOM 916 C C . GLN A 1 122 ? -16.148 -8.191 13.219 1.00 20.29 ? 122 GLN A C 1 ATOM 917 O O . GLN A 1 122 ? -16.653 -9.193 12.721 1.00 19.89 ? 122 GLN A O 1 ATOM 918 C CB . GLN A 1 122 ? -14.695 -6.761 11.780 1.00 20.23 ? 122 GLN A CB 1 ATOM 919 C CG . GLN A 1 122 ? -14.561 -5.450 11.055 1.00 23.67 ? 122 GLN A CG 1 ATOM 920 C CD . GLN A 1 122 ? -13.552 -5.494 9.954 1.00 30.02 ? 122 GLN A CD 1 ATOM 921 O OE1 . GLN A 1 122 ? -12.329 -5.592 10.209 1.00 32.08 ? 122 GLN A OE1 1 ATOM 922 N NE2 . GLN A 1 122 ? -14.045 -5.399 8.697 1.00 30.65 ? 122 GLN A NE2 1 ATOM 923 N N . ARG A 1 123 ? -15.581 -8.169 14.437 1.00 19.98 ? 123 ARG A N 1 ATOM 924 C CA . ARG A 1 123 ? -15.544 -9.337 15.284 1.00 19.77 ? 123 ARG A CA 1 ATOM 925 C C . ARG A 1 123 ? -16.967 -9.812 15.529 1.00 19.94 ? 123 ARG A C 1 ATOM 926 O O . ARG A 1 123 ? -17.240 -11.020 15.618 1.00 20.27 ? 123 ARG A O 1 ATOM 927 C CB . ARG A 1 123 ? -14.865 -9.000 16.617 1.00 19.75 ? 123 ARG A CB 1 ATOM 928 C CG . ARG A 1 123 ? -14.663 -10.208 17.496 1.00 19.56 ? 123 ARG A CG 1 ATOM 929 C CD . ARG A 1 123 ? -13.851 -9.903 18.740 1.00 22.29 ? 123 ARG A CD 1 ATOM 930 N NE . ARG A 1 123 ? -13.982 -10.989 19.680 1.00 21.93 ? 123 ARG A NE 1 ATOM 931 C CZ . ARG A 1 123 ? -13.218 -12.083 19.717 1.00 22.91 ? 123 ARG A CZ 1 ATOM 932 N NH1 . ARG A 1 123 ? -12.181 -12.252 18.903 1.00 20.63 ? 123 ARG A NH1 1 ATOM 933 N NH2 . ARG A 1 123 ? -13.505 -13.019 20.608 1.00 24.88 ? 123 ARG A NH2 1 ATOM 934 N N . TYR A 1 124 ? -17.886 -8.873 15.637 1.00 19.74 ? 124 TYR A N 1 ATOM 935 C CA . TYR A 1 124 ? -19.249 -9.252 15.964 1.00 20.30 ? 124 TYR A CA 1 ATOM 936 C C . TYR A 1 124 ? -20.228 -8.880 14.844 1.00 20.64 ? 124 TYR A C 1 ATOM 937 O O . TYR A 1 124 ? -21.452 -8.659 15.086 1.00 19.31 ? 124 TYR A O 1 ATOM 938 C CB . TYR A 1 124 ? -19.658 -8.653 17.315 1.00 20.24 ? 124 TYR A CB 1 ATOM 939 C CG . TYR A 1 124 ? -18.706 -9.058 18.413 1.00 19.90 ? 124 TYR A CG 1 ATOM 940 C CD1 . TYR A 1 124 ? -18.776 -10.322 18.989 1.00 19.20 ? 124 TYR A CD1 1 ATOM 941 C CD2 . TYR A 1 124 ? -17.719 -8.169 18.864 1.00 19.52 ? 124 TYR A CD2 1 ATOM 942 C CE1 . TYR A 1 124 ? -17.866 -10.706 19.996 1.00 19.09 ? 124 TYR A CE1 1 ATOM 943 C CE2 . TYR A 1 124 ? -16.852 -8.517 19.873 1.00 19.62 ? 124 TYR A CE2 1 ATOM 944 C CZ . TYR A 1 124 ? -16.918 -9.780 20.428 1.00 19.59 ? 124 TYR A CZ 1 ATOM 945 O OH . TYR A 1 124 ? -16.028 -10.102 21.406 1.00 18.16 ? 124 TYR A OH 1 ATOM 946 N N . GLU A 1 125 ? -19.658 -8.857 13.629 1.00 20.44 ? 125 GLU A N 1 ATOM 947 C CA . GLU A 1 125 ? -20.376 -8.564 12.369 1.00 21.14 ? 125 GLU A CA 1 ATOM 948 C C . GLU A 1 125 ? -21.786 -9.168 12.291 1.00 21.23 ? 125 GLU A C 1 ATOM 949 O O . GLU A 1 125 ? -22.758 -8.492 11.885 1.00 21.67 ? 125 GLU A O 1 ATOM 950 C CB . GLU A 1 125 ? -19.533 -9.015 11.162 1.00 21.21 ? 125 GLU A CB 1 ATOM 951 C CG . GLU A 1 125 ? -19.958 -8.404 9.849 1.00 21.14 ? 125 GLU A CG 1 ATOM 952 C CD . GLU A 1 125 ? -21.108 -9.148 9.241 1.00 19.84 ? 125 GLU A CD 1 ATOM 953 O OE1 . GLU A 1 125 ? -21.131 -10.386 9.330 1.00 17.82 ? 125 GLU A OE1 1 ATOM 954 O OE2 . GLU A 1 125 ? -21.998 -8.491 8.690 1.00 20.73 ? 125 GLU A OE2 1 ATOM 955 N N . SER A 1 126 ? -21.923 -10.418 12.701 1.00 20.15 ? 126 SER A N 1 ATOM 956 C CA . SER A 1 126 ? -23.184 -11.051 12.455 1.00 20.64 ? 126 SER A CA 1 ATOM 957 C C . SER A 1 126 ? -24.245 -10.494 13.418 1.00 19.54 ? 126 SER A C 1 ATOM 958 O O . SER A 1 126 ? -25.432 -10.837 13.289 1.00 18.98 ? 126 SER A O 1 ATOM 959 C CB . SER A 1 126 ? -23.092 -12.595 12.403 1.00 20.71 ? 126 SER A CB 1 ATOM 960 O OG . SER A 1 126 ? -23.303 -13.120 13.688 1.00 23.80 ? 126 SER A OG 1 ATOM 961 N N . LEU A 1 127 ? -23.823 -9.573 14.306 1.00 18.51 ? 127 LEU A N 1 ATOM 962 C CA . LEU A 1 127 ? -24.756 -8.814 15.177 1.00 17.05 ? 127 LEU A CA 1 ATOM 963 C C . LEU A 1 127 ? -24.732 -7.313 14.967 1.00 18.14 ? 127 LEU A C 1 ATOM 964 O O . LEU A 1 127 ? -25.767 -6.639 15.127 1.00 18.66 ? 127 LEU A O 1 ATOM 965 C CB . LEU A 1 127 ? -24.490 -9.095 16.642 1.00 17.00 ? 127 LEU A CB 1 ATOM 966 C CG . LEU A 1 127 ? -24.477 -10.533 17.148 1.00 13.44 ? 127 LEU A CG 1 ATOM 967 C CD1 . LEU A 1 127 ? -23.925 -10.528 18.535 1.00 9.21 ? 127 LEU A CD1 1 ATOM 968 C CD2 . LEU A 1 127 ? -25.851 -11.039 17.163 1.00 14.15 ? 127 LEU A CD2 1 ATOM 969 N N . THR A 1 128 ? -23.564 -6.789 14.585 1.00 18.48 ? 128 THR A N 1 ATOM 970 C CA . THR A 1 128 ? -23.350 -5.380 14.400 1.00 18.29 ? 128 THR A CA 1 ATOM 971 C C . THR A 1 128 ? -23.996 -4.919 13.063 1.00 19.76 ? 128 THR A C 1 ATOM 972 O O . THR A 1 128 ? -24.174 -3.731 12.785 1.00 19.57 ? 128 THR A O 1 ATOM 973 C CB . THR A 1 128 ? -21.812 -5.002 14.532 1.00 18.32 ? 128 THR A CB 1 ATOM 974 O OG1 . THR A 1 128 ? -21.017 -5.678 13.556 1.00 17.83 ? 128 THR A OG1 1 ATOM 975 C CG2 . THR A 1 128 ? -21.273 -5.370 15.874 1.00 17.88 ? 128 THR A CG2 1 ATOM 976 N N . ARG A 1 129 ? -24.367 -5.883 12.242 1.00 21.22 ? 129 ARG A N 1 ATOM 977 C CA . ARG A 1 129 ? -24.978 -5.572 10.986 1.00 21.85 ? 129 ARG A CA 1 ATOM 978 C C . ARG A 1 129 ? -26.383 -5.058 11.136 1.00 22.38 ? 129 ARG A C 1 ATOM 979 O O . ARG A 1 129 ? -26.825 -4.315 10.270 1.00 22.37 ? 129 ARG A O 1 ATOM 980 C CB . ARG A 1 129 ? -24.936 -6.760 10.061 1.00 22.28 ? 129 ARG A CB 1 ATOM 981 C CG . ARG A 1 129 ? -25.907 -7.888 10.356 1.00 23.02 ? 129 ARG A CG 1 ATOM 982 C CD . ARG A 1 129 ? -25.142 -9.120 9.972 1.00 24.80 ? 129 ARG A CD 1 ATOM 983 N NE . ARG A 1 129 ? -25.949 -10.123 9.334 1.00 25.76 ? 129 ARG A NE 1 ATOM 984 C CZ . ARG A 1 129 ? -25.460 -11.204 8.733 1.00 26.00 ? 129 ARG A CZ 1 ATOM 985 N NH1 . ARG A 1 129 ? -24.150 -11.436 8.679 1.00 24.98 ? 129 ARG A NH1 1 ATOM 986 N NH2 . ARG A 1 129 ? -26.309 -12.051 8.172 1.00 26.31 ? 129 ARG A NH2 1 ATOM 987 N N . ASN A 1 130 ? -27.072 -5.380 12.228 1.00 22.63 ? 130 ASN A N 1 ATOM 988 C CA . ASN A 1 130 ? -28.472 -4.915 12.328 1.00 23.41 ? 130 ASN A CA 1 ATOM 989 C C . ASN A 1 130 ? -28.956 -4.572 13.727 1.00 23.36 ? 130 ASN A C 1 ATOM 990 O O . ASN A 1 130 ? -30.154 -4.444 13.972 1.00 24.45 ? 130 ASN A O 1 ATOM 991 C CB . ASN A 1 130 ? -29.411 -5.938 11.711 1.00 23.88 ? 130 ASN A CB 1 ATOM 992 C CG . ASN A 1 130 ? -29.438 -7.236 12.488 1.00 25.58 ? 130 ASN A CG 1 ATOM 993 O OD1 . ASN A 1 130 ? -28.616 -7.441 13.388 1.00 27.22 ? 130 ASN A OD1 1 ATOM 994 N ND2 . ASN A 1 130 ? -30.357 -8.134 12.131 1.00 24.37 ? 130 ASN A ND2 1 ATOM 995 N N . ILE A 1 131 ? -28.015 -4.446 14.650 1.00 23.15 ? 131 ILE A N 1 ATOM 996 C CA . ILE A 1 131 ? -28.311 -4.017 16.002 1.00 22.23 ? 131 ILE A CA 1 ATOM 997 C C . ILE A 1 131 ? -27.454 -2.809 16.332 1.00 22.12 ? 131 ILE A C 1 ATOM 998 O O . ILE A 1 131 ? -26.227 -2.813 16.167 1.00 22.01 ? 131 ILE A O 1 ATOM 999 C CB . ILE A 1 131 ? -28.123 -5.147 17.050 1.00 22.43 ? 131 ILE A CB 1 ATOM 1000 C CG1 . ILE A 1 131 ? -29.306 -6.135 16.950 1.00 22.19 ? 131 ILE A CG1 1 ATOM 1001 C CG2 . ILE A 1 131 ? -28.151 -4.578 18.458 1.00 21.38 ? 131 ILE A CG2 1 ATOM 1002 C CD1 . ILE A 1 131 ? -28.917 -7.563 17.053 1.00 20.95 ? 131 ILE A CD1 1 ATOM 1003 N N . VAL A 1 132 ? -28.134 -1.775 16.803 1.00 21.59 ? 132 VAL A N 1 ATOM 1004 C CA . VAL A 1 132 ? -27.507 -0.568 17.237 1.00 20.99 ? 132 VAL A CA 1 ATOM 1005 C C . VAL A 1 132 ? -27.171 -0.760 18.710 1.00 20.61 ? 132 VAL A C 1 ATOM 1006 O O . VAL A 1 132 ? -28.084 -0.956 19.543 1.00 20.12 ? 132 VAL A O 1 ATOM 1007 C CB . VAL A 1 132 ? -28.461 0.608 16.998 1.00 21.03 ? 132 VAL A CB 1 ATOM 1008 C CG1 . VAL A 1 132 ? -27.847 1.920 17.445 1.00 21.16 ? 132 VAL A CG1 1 ATOM 1009 C CG2 . VAL A 1 132 ? -28.776 0.672 15.486 1.00 21.52 ? 132 VAL A CG2 1 ATOM 1010 N N . PRO A 1 133 ? -25.857 -0.713 19.040 1.00 19.56 ? 133 PRO A N 1 ATOM 1011 C CA . PRO A 1 133 ? -25.381 -0.884 20.418 1.00 19.29 ? 133 PRO A CA 1 ATOM 1012 C C . PRO A 1 133 ? -25.806 0.257 21.339 1.00 19.25 ? 133 PRO A C 1 ATOM 1013 O O . PRO A 1 133 ? -25.915 1.427 20.900 1.00 18.70 ? 133 PRO A O 1 ATOM 1014 C CB . PRO A 1 133 ? -23.852 -0.908 20.274 1.00 18.94 ? 133 PRO A CB 1 ATOM 1015 C CG . PRO A 1 133 ? -23.586 -0.989 18.801 1.00 19.50 ? 133 PRO A CG 1 ATOM 1016 C CD . PRO A 1 133 ? -24.758 -0.347 18.146 1.00 19.63 ? 133 PRO A CD 1 ATOM 1017 N N . PHE A 1 134 ? -26.088 -0.082 22.595 1.00 18.03 ? 134 PHE A N 1 ATOM 1018 C CA . PHE A 1 134 ? -26.370 0.967 23.553 1.00 17.52 ? 134 PHE A CA 1 ATOM 1019 C C . PHE A 1 134 ? -25.067 1.478 24.166 1.00 16.53 ? 134 PHE A C 1 ATOM 1020 O O . PHE A 1 134 ? -24.239 0.705 24.721 1.00 15.16 ? 134 PHE A O 1 ATOM 1021 C CB . PHE A 1 134 ? -27.382 0.553 24.636 1.00 17.32 ? 134 PHE A CB 1 ATOM 1022 C CG . PHE A 1 134 ? -27.784 1.692 25.534 1.00 18.10 ? 134 PHE A CG 1 ATOM 1023 C CD1 . PHE A 1 134 ? -28.756 2.600 25.139 1.00 17.55 ? 134 PHE A CD1 1 ATOM 1024 C CD2 . PHE A 1 134 ? -27.180 1.855 26.778 1.00 18.80 ? 134 PHE A CD2 1 ATOM 1025 C CE1 . PHE A 1 134 ? -29.135 3.655 25.989 1.00 19.22 ? 134 PHE A CE1 1 ATOM 1026 C CE2 . PHE A 1 134 ? -27.536 2.912 27.631 1.00 19.30 ? 134 PHE A CE2 1 ATOM 1027 C CZ . PHE A 1 134 ? -28.514 3.813 27.237 1.00 19.31 ? 134 PHE A CZ 1 ATOM 1028 N N . ILE A 1 135 ? -24.898 2.793 24.091 1.00 16.12 ? 135 ILE A N 1 ATOM 1029 C CA . ILE A 1 135 ? -23.556 3.374 24.332 1.00 16.96 ? 135 ILE A CA 1 ATOM 1030 C C . ILE A 1 135 ? -23.456 4.419 25.453 1.00 17.39 ? 135 ILE A C 1 ATOM 1031 O O . ILE A 1 135 ? -24.141 5.478 25.416 1.00 17.01 ? 135 ILE A O 1 ATOM 1032 C CB . ILE A 1 135 ? -22.948 3.948 23.046 1.00 16.95 ? 135 ILE A CB 1 ATOM 1033 C CG1 . ILE A 1 135 ? -22.807 2.845 21.996 1.00 16.43 ? 135 ILE A CG1 1 ATOM 1034 C CG2 . ILE A 1 135 ? -21.586 4.642 23.357 1.00 16.08 ? 135 ILE A CG2 1 ATOM 1035 C CD1 . ILE A 1 135 ? -22.016 3.290 20.723 1.00 18.70 ? 135 ILE A CD1 1 ATOM 1036 N N . ARG A 1 136 ? -22.577 4.135 26.422 1.00 17.55 ? 136 ARG A N 1 ATOM 1037 C CA . ARG A 1 136 ? -22.356 5.060 27.530 1.00 17.50 ? 136 ARG A CA 1 ATOM 1038 C C . ARG A 1 136 ? -20.927 5.609 27.614 1.00 17.56 ? 136 ARG A C 1 ATOM 1039 O O . ARG A 1 136 ? -19.988 4.987 27.130 1.00 17.34 ? 136 ARG A O 1 ATOM 1040 C CB . ARG A 1 136 ? -22.777 4.419 28.826 1.00 17.67 ? 136 ARG A CB 1 ATOM 1041 C CG . ARG A 1 136 ? -24.259 4.184 28.957 1.00 16.38 ? 136 ARG A CG 1 ATOM 1042 C CD . ARG A 1 136 ? -24.552 3.650 30.346 1.00 16.82 ? 136 ARG A CD 1 ATOM 1043 N NE . ARG A 1 136 ? -23.648 2.533 30.646 1.00 16.85 ? 136 ARG A NE 1 ATOM 1044 C CZ . ARG A 1 136 ? -23.510 1.963 31.840 1.00 15.97 ? 136 ARG A CZ 1 ATOM 1045 N NH1 . ARG A 1 136 ? -24.248 2.359 32.848 1.00 15.05 ? 136 ARG A NH1 1 ATOM 1046 N NH2 . ARG A 1 136 ? -22.639 0.984 32.010 1.00 17.29 ? 136 ARG A NH2 1 ATOM 1047 N N . SER A 1 137 ? -20.768 6.789 28.212 1.00 18.40 ? 137 SER A N 1 ATOM 1048 C CA . SER A 1 137 ? -19.443 7.396 28.330 1.00 19.71 ? 137 SER A CA 1 ATOM 1049 C C . SER A 1 137 ? -19.308 8.196 29.596 1.00 20.11 ? 137 SER A C 1 ATOM 1050 O O . SER A 1 137 ? -20.146 9.032 29.899 1.00 21.70 ? 137 SER A O 1 ATOM 1051 C CB . SER A 1 137 ? -19.132 8.299 27.125 1.00 20.49 ? 137 SER A CB 1 ATOM 1052 O OG . SER A 1 137 ? -17.796 8.824 27.120 1.00 20.45 ? 137 SER A OG 1 ATOM 1053 N N . SER A 1 138 ? -18.231 7.974 30.334 1.00 20.82 ? 138 SER A N 1 ATOM 1054 C CA . SER A 1 138 ? -17.912 8.872 31.445 1.00 21.17 ? 138 SER A CA 1 ATOM 1055 C C . SER A 1 138 ? -17.820 10.299 30.873 1.00 21.34 ? 138 SER A C 1 ATOM 1056 O O . SER A 1 138 ? -17.593 10.462 29.690 1.00 20.70 ? 138 SER A O 1 ATOM 1057 C CB . SER A 1 138 ? -16.590 8.458 32.103 1.00 20.36 ? 138 SER A CB 1 ATOM 1058 O OG . SER A 1 138 ? -16.399 9.154 33.326 1.00 20.54 ? 138 SER A OG 1 ATOM 1059 N N . GLY A 1 139 ? -17.988 11.326 31.697 1.00 22.36 ? 139 GLY A N 1 ATOM 1060 C CA . GLY A 1 139 ? -17.937 12.685 31.165 1.00 23.77 ? 139 GLY A CA 1 ATOM 1061 C C . GLY A 1 139 ? -16.592 13.383 31.245 1.00 25.06 ? 139 GLY A C 1 ATOM 1062 O O . GLY A 1 139 ? -16.316 14.088 32.223 1.00 27.31 ? 139 GLY A O 1 ATOM 1063 N N . SER A 1 140 ? -15.753 13.225 30.235 1.00 24.41 ? 140 SER A N 1 ATOM 1064 C CA . SER A 1 140 ? -14.458 13.907 30.187 1.00 23.74 ? 140 SER A CA 1 ATOM 1065 C C . SER A 1 140 ? -14.140 14.104 28.702 1.00 23.44 ? 140 SER A C 1 ATOM 1066 O O . SER A 1 140 ? -14.284 13.169 27.923 1.00 23.25 ? 140 SER A O 1 ATOM 1067 C CB . SER A 1 140 ? -13.391 13.048 30.867 1.00 23.85 ? 140 SER A CB 1 ATOM 1068 O OG . SER A 1 140 ? -12.055 13.396 30.461 1.00 24.27 ? 140 SER A OG 1 ATOM 1069 N N . SER A 1 141 ? -13.723 15.295 28.295 1.00 22.45 ? 141 SER A N 1 ATOM 1070 C CA . SER A 1 141 ? -13.585 15.545 26.873 1.00 22.74 ? 141 SER A CA 1 ATOM 1071 C C . SER A 1 141 ? -12.919 14.378 26.158 1.00 21.93 ? 141 SER A C 1 ATOM 1072 O O . SER A 1 141 ? -13.413 13.950 25.116 1.00 22.49 ? 141 SER A O 1 ATOM 1073 C CB . SER A 1 141 ? -12.778 16.798 26.577 1.00 22.43 ? 141 SER A CB 1 ATOM 1074 O OG . SER A 1 141 ? -13.134 17.800 27.471 1.00 27.72 ? 141 SER A OG 1 ATOM 1075 N N . ARG A 1 142 ? -11.789 13.887 26.674 1.00 21.06 ? 142 ARG A N 1 ATOM 1076 C CA . ARG A 1 142 ? -11.058 12.806 25.979 1.00 20.35 ? 142 ARG A CA 1 ATOM 1077 C C . ARG A 1 142 ? -11.835 11.462 25.879 1.00 19.88 ? 142 ARG A C 1 ATOM 1078 O O . ARG A 1 142 ? -11.675 10.671 24.911 1.00 19.35 ? 142 ARG A O 1 ATOM 1079 C CB . ARG A 1 142 ? -9.681 12.617 26.574 1.00 21.02 ? 142 ARG A CB 1 ATOM 1080 C CG . ARG A 1 142 ? -9.610 12.188 28.085 1.00 23.16 ? 142 ARG A CG 1 ATOM 1081 C CD . ARG A 1 142 ? -8.142 12.127 28.535 1.00 28.92 ? 142 ARG A CD 1 ATOM 1082 N NE . ARG A 1 142 ? -7.979 11.796 29.953 1.00 34.90 ? 142 ARG A NE 1 ATOM 1083 C CZ . ARG A 1 142 ? -7.981 12.690 30.943 1.00 38.45 ? 142 ARG A CZ 1 ATOM 1084 N NH1 . ARG A 1 142 ? -8.146 13.988 30.693 1.00 38.03 ? 142 ARG A NH1 1 ATOM 1085 N NH2 . ARG A 1 142 ? -7.826 12.277 32.194 1.00 39.75 ? 142 ARG A NH2 1 ATOM 1086 N N . VAL A 1 143 ? -12.705 11.216 26.850 1.00 18.97 ? 143 VAL A N 1 ATOM 1087 C CA . VAL A 1 143 ? -13.439 9.952 26.878 1.00 19.59 ? 143 VAL A CA 1 ATOM 1088 C C . VAL A 1 143 ? -14.595 9.996 25.840 1.00 18.68 ? 143 VAL A C 1 ATOM 1089 O O . VAL A 1 143 ? -14.668 9.141 24.959 1.00 17.72 ? 143 VAL A O 1 ATOM 1090 C CB . VAL A 1 143 ? -13.862 9.541 28.322 1.00 19.50 ? 143 VAL A CB 1 ATOM 1091 C CG1 . VAL A 1 143 ? -14.600 8.207 28.329 1.00 18.80 ? 143 VAL A CG1 1 ATOM 1092 C CG2 . VAL A 1 143 ? -12.650 9.420 29.151 1.00 19.65 ? 143 VAL A CG2 1 ATOM 1093 N N . ILE A 1 144 ? -15.405 11.049 25.946 1.00 19.20 ? 144 ILE A N 1 ATOM 1094 C CA . ILE A 1 144 ? -16.458 11.463 25.000 1.00 19.21 ? 144 ILE A CA 1 ATOM 1095 C C . ILE A 1 144 ? -15.993 11.504 23.545 1.00 18.86 ? 144 ILE A C 1 ATOM 1096 O O . ILE A 1 144 ? -16.603 10.890 22.647 1.00 19.56 ? 144 ILE A O 1 ATOM 1097 C CB . ILE A 1 144 ? -16.974 12.851 25.367 1.00 19.49 ? 144 ILE A CB 1 ATOM 1098 C CG1 . ILE A 1 144 ? -17.792 12.807 26.653 1.00 21.56 ? 144 ILE A CG1 1 ATOM 1099 C CG2 . ILE A 1 144 ? -17.871 13.384 24.304 1.00 20.80 ? 144 ILE A CG2 1 ATOM 1100 C CD1 . ILE A 1 144 ? -18.138 14.229 27.223 1.00 24.52 ? 144 ILE A CD1 1 ATOM 1101 N N . ALA A 1 145 ? -14.907 12.211 23.312 1.00 17.81 ? 145 ALA A N 1 ATOM 1102 C CA . ALA A 1 145 ? -14.320 12.232 21.984 1.00 17.06 ? 145 ALA A CA 1 ATOM 1103 C C . ALA A 1 145 ? -13.932 10.851 21.495 1.00 16.19 ? 145 ALA A C 1 ATOM 1104 O O . ALA A 1 145 ? -14.146 10.512 20.310 1.00 16.66 ? 145 ALA A O 1 ATOM 1105 C CB . ALA A 1 145 ? -13.129 13.183 21.933 1.00 16.57 ? 145 ALA A CB 1 ATOM 1106 N N . SER A 1 146 ? -13.343 10.057 22.387 1.00 16.12 ? 146 SER A N 1 ATOM 1107 C CA . SER A 1 146 ? -12.884 8.677 22.039 1.00 15.36 ? 146 SER A CA 1 ATOM 1108 C C . SER A 1 146 ? -14.062 7.759 21.728 1.00 14.98 ? 146 SER A C 1 ATOM 1109 O O . SER A 1 146 ? -14.028 7.029 20.754 1.00 14.98 ? 146 SER A O 1 ATOM 1110 C CB . SER A 1 146 ? -12.110 8.070 23.184 1.00 15.70 ? 146 SER A CB 1 ATOM 1111 O OG . SER A 1 146 ? -10.802 8.556 23.259 1.00 16.57 ? 146 SER A OG 1 ATOM 1112 N N . GLY A 1 147 ? -15.104 7.828 22.556 1.00 14.14 ? 147 GLY A N 1 ATOM 1113 C CA . GLY A 1 147 ? -16.353 7.194 22.262 1.00 14.82 ? 147 GLY A CA 1 ATOM 1114 C C . GLY A 1 147 ? -16.777 7.491 20.829 1.00 16.28 ? 147 GLY A C 1 ATOM 1115 O O . GLY A 1 147 ? -17.064 6.545 20.032 1.00 16.65 ? 147 GLY A O 1 ATOM 1116 N N . LYS A 1 148 ? -16.780 8.778 20.477 1.00 16.24 ? 148 LYS A N 1 ATOM 1117 C CA . LYS A 1 148 ? -17.201 9.210 19.154 1.00 16.66 ? 148 LYS A CA 1 ATOM 1118 C C . LYS A 1 148 ? -16.255 8.798 18.020 1.00 17.18 ? 148 LYS A C 1 ATOM 1119 O O . LYS A 1 148 ? -16.696 8.560 16.905 1.00 18.49 ? 148 LYS A O 1 ATOM 1120 C CB . LYS A 1 148 ? -17.433 10.723 19.164 1.00 17.52 ? 148 LYS A CB 1 ATOM 1121 C CG . LYS A 1 148 ? -18.718 11.148 19.915 1.00 17.43 ? 148 LYS A CG 1 ATOM 1122 C CD . LYS A 1 148 ? -18.816 12.655 20.013 1.00 19.66 ? 148 LYS A CD 1 ATOM 1123 C CE . LYS A 1 148 ? -19.921 13.067 20.975 1.00 21.88 ? 148 LYS A CE 1 ATOM 1124 N NZ . LYS A 1 148 ? -19.559 14.333 21.757 1.00 20.63 ? 148 LYS A NZ 1 ATOM 1125 N N . LYS A 1 149 ? -14.957 8.684 18.271 1.00 17.55 ? 149 LYS A N 1 ATOM 1126 C CA . LYS A 1 149 ? -14.084 8.156 17.230 1.00 17.86 ? 149 LYS A CA 1 ATOM 1127 C C . LYS A 1 149 ? -14.291 6.652 17.016 1.00 19.04 ? 149 LYS A C 1 ATOM 1128 O O . LYS A 1 149 ? -14.060 6.109 15.912 1.00 20.54 ? 149 LYS A O 1 ATOM 1129 C CB . LYS A 1 149 ? -12.631 8.428 17.562 1.00 18.12 ? 149 LYS A CB 1 ATOM 1130 C CG . LYS A 1 149 ? -12.206 9.833 17.343 1.00 17.55 ? 149 LYS A CG 1 ATOM 1131 C CD . LYS A 1 149 ? -11.794 10.073 15.895 1.00 18.69 ? 149 LYS A CD 1 ATOM 1132 C CE . LYS A 1 149 ? -11.865 11.568 15.550 1.00 20.01 ? 149 LYS A CE 1 ATOM 1133 N NZ . LYS A 1 149 ? -11.707 11.859 14.122 1.00 19.67 ? 149 LYS A NZ 1 ATOM 1134 N N . PHE A 1 150 ? -14.705 5.963 18.070 1.00 18.72 ? 150 PHE A N 1 ATOM 1135 C CA . PHE A 1 150 ? -15.029 4.567 17.959 1.00 18.60 ? 150 PHE A CA 1 ATOM 1136 C C . PHE A 1 150 ? -16.318 4.437 17.136 1.00 18.68 ? 150 PHE A C 1 ATOM 1137 O O . PHE A 1 150 ? -16.374 3.628 16.224 1.00 18.63 ? 150 PHE A O 1 ATOM 1138 C CB . PHE A 1 150 ? -15.117 3.954 19.371 1.00 18.98 ? 150 PHE A CB 1 ATOM 1139 C CG . PHE A 1 150 ? -15.686 2.530 19.439 1.00 18.22 ? 150 PHE A CG 1 ATOM 1140 C CD1 . PHE A 1 150 ? -17.022 2.263 19.146 1.00 18.77 ? 150 PHE A CD1 1 ATOM 1141 C CD2 . PHE A 1 150 ? -14.889 1.469 19.879 1.00 18.73 ? 150 PHE A CD2 1 ATOM 1142 C CE1 . PHE A 1 150 ? -17.513 0.950 19.264 1.00 18.75 ? 150 PHE A CE1 1 ATOM 1143 C CE2 . PHE A 1 150 ? -15.380 0.179 20.002 1.00 16.64 ? 150 PHE A CE2 1 ATOM 1144 C CZ . PHE A 1 150 ? -16.684 -0.082 19.698 1.00 16.59 ? 150 PHE A CZ 1 ATOM 1145 N N . ILE A 1 151 ? -17.331 5.252 17.434 1.00 18.92 ? 151 ILE A N 1 ATOM 1146 C CA . ILE A 1 151 ? -18.620 5.188 16.712 1.00 19.62 ? 151 ILE A CA 1 ATOM 1147 C C . ILE A 1 151 ? -18.413 5.533 15.270 1.00 20.52 ? 151 ILE A C 1 ATOM 1148 O O . ILE A 1 151 ? -19.050 4.963 14.399 1.00 21.34 ? 151 ILE A O 1 ATOM 1149 C CB . ILE A 1 151 ? -19.660 6.174 17.257 1.00 19.56 ? 151 ILE A CB 1 ATOM 1150 C CG1 . ILE A 1 151 ? -20.243 5.639 18.561 1.00 15.81 ? 151 ILE A CG1 1 ATOM 1151 C CG2 . ILE A 1 151 ? -20.755 6.497 16.160 1.00 17.91 ? 151 ILE A CG2 1 ATOM 1152 C CD1 . ILE A 1 151 ? -20.933 6.726 19.391 1.00 15.21 ? 151 ILE A CD1 1 ATOM 1153 N N . GLU A 1 152 ? -17.502 6.469 15.033 1.00 21.85 ? 152 GLU A N 1 ATOM 1154 C CA . GLU A 1 152 ? -17.053 6.840 13.675 1.00 22.03 ? 152 GLU A CA 1 ATOM 1155 C C . GLU A 1 152 ? -16.536 5.677 12.834 1.00 21.93 ? 152 GLU A C 1 ATOM 1156 O O . GLU A 1 152 ? -16.979 5.481 11.718 1.00 21.86 ? 152 GLU A O 1 ATOM 1157 C CB . GLU A 1 152 ? -15.966 7.889 13.784 1.00 22.25 ? 152 GLU A CB 1 ATOM 1158 C CG . GLU A 1 152 ? -15.879 8.796 12.576 1.00 23.45 ? 152 GLU A CG 1 ATOM 1159 C CD . GLU A 1 152 ? -14.745 9.827 12.647 1.00 23.90 ? 152 GLU A CD 1 ATOM 1160 O OE1 . GLU A 1 152 ? -14.528 10.469 13.710 1.00 23.79 ? 152 GLU A OE1 1 ATOM 1161 O OE2 . GLU A 1 152 ? -14.080 10.015 11.600 1.00 25.80 ? 152 GLU A OE2 1 ATOM 1162 N N . GLY A 1 153 ? -15.577 4.920 13.354 1.00 22.01 ? 153 GLY A N 1 ATOM 1163 C CA . GLY A 1 153 ? -15.057 3.767 12.638 1.00 21.60 ? 153 GLY A CA 1 ATOM 1164 C C . GLY A 1 153 ? -16.072 2.623 12.512 1.00 22.08 ? 153 GLY A C 1 ATOM 1165 O O . GLY A 1 153 ? -16.186 2.005 11.450 1.00 22.68 ? 153 GLY A O 1 ATOM 1166 N N . PHE A 1 154 ? -16.810 2.332 13.577 1.00 21.78 ? 154 PHE A N 1 ATOM 1167 C CA . PHE A 1 154 ? -17.931 1.361 13.525 1.00 21.97 ? 154 PHE A CA 1 ATOM 1168 C C . PHE A 1 154 ? -18.887 1.717 12.384 1.00 22.79 ? 154 PHE A C 1 ATOM 1169 O O . PHE A 1 154 ? -19.267 0.849 11.597 1.00 22.42 ? 154 PHE A O 1 ATOM 1170 C CB . PHE A 1 154 ? -18.665 1.377 14.866 1.00 21.29 ? 154 PHE A CB 1 ATOM 1171 C CG . PHE A 1 154 ? -19.810 0.383 15.015 1.00 19.59 ? 154 PHE A CG 1 ATOM 1172 C CD1 . PHE A 1 154 ? -21.088 0.664 14.519 1.00 16.29 ? 154 PHE A CD1 1 ATOM 1173 C CD2 . PHE A 1 154 ? -19.649 -0.764 15.783 1.00 17.97 ? 154 PHE A CD2 1 ATOM 1174 C CE1 . PHE A 1 154 ? -22.146 -0.232 14.708 1.00 13.08 ? 154 PHE A CE1 1 ATOM 1175 C CE2 . PHE A 1 154 ? -20.723 -1.655 15.998 1.00 14.85 ? 154 PHE A CE2 1 ATOM 1176 C CZ . PHE A 1 154 ? -21.954 -1.385 15.465 1.00 14.47 ? 154 PHE A CZ 1 ATOM 1177 N N . GLN A 1 155 ? -19.254 2.997 12.282 1.00 23.56 ? 155 GLN A N 1 ATOM 1178 C CA . GLN A 1 155 ? -20.209 3.443 11.270 1.00 24.88 ? 155 GLN A CA 1 ATOM 1179 C C . GLN A 1 155 ? -19.638 3.362 9.840 1.00 24.10 ? 155 GLN A C 1 ATOM 1180 O O . GLN A 1 155 ? -20.369 3.042 8.899 1.00 24.09 ? 155 GLN A O 1 ATOM 1181 C CB . GLN A 1 155 ? -20.778 4.836 11.627 1.00 25.80 ? 155 GLN A CB 1 ATOM 1182 C CG . GLN A 1 155 ? -21.970 5.330 10.737 1.00 32.99 ? 155 GLN A CG 1 ATOM 1183 C CD . GLN A 1 155 ? -23.195 4.346 10.690 1.00 39.30 ? 155 GLN A CD 1 ATOM 1184 O OE1 . GLN A 1 155 ? -23.874 4.163 11.703 1.00 44.06 ? 155 GLN A OE1 1 ATOM 1185 N NE2 . GLN A 1 155 ? -23.465 3.731 9.504 1.00 36.05 ? 155 GLN A NE2 1 ATOM 1186 N N . SER A 1 156 ? -18.335 3.614 9.689 1.00 23.07 ? 156 SER A N 1 ATOM 1187 C CA . SER A 1 156 ? -17.653 3.456 8.387 1.00 22.82 ? 156 SER A CA 1 ATOM 1188 C C . SER A 1 156 ? -17.580 2.032 7.882 1.00 21.72 ? 156 SER A C 1 ATOM 1189 O O . SER A 1 156 ? -17.553 1.780 6.680 1.00 22.39 ? 156 SER A O 1 ATOM 1190 C CB . SER A 1 156 ? -16.222 4.018 8.426 1.00 22.57 ? 156 SER A CB 1 ATOM 1191 O OG . SER A 1 156 ? -16.311 5.425 8.370 1.00 24.81 ? 156 SER A OG 1 ATOM 1192 N N . THR A 1 157 ? -17.470 1.108 8.804 1.00 20.52 ? 157 THR A N 1 ATOM 1193 C CA . THR A 1 157 ? -17.383 -0.286 8.452 1.00 20.24 ? 157 THR A CA 1 ATOM 1194 C C . THR A 1 157 ? -18.775 -0.808 8.116 1.00 20.22 ? 157 THR A C 1 ATOM 1195 O O . THR A 1 157 ? -18.918 -1.547 7.162 1.00 20.67 ? 157 THR A O 1 ATOM 1196 C CB . THR A 1 157 ? -16.790 -1.069 9.605 1.00 19.75 ? 157 THR A CB 1 ATOM 1197 O OG1 . THR A 1 157 ? -15.679 -0.335 10.096 1.00 19.37 ? 157 THR A OG1 1 ATOM 1198 C CG2 . THR A 1 157 ? -16.350 -2.439 9.163 1.00 18.00 ? 157 THR A CG2 1 ATOM 1199 N N . LYS A 1 158 ? -19.785 -0.372 8.875 1.00 20.45 ? 158 LYS A N 1 ATOM 1200 C CA . LYS A 1 158 ? -21.183 -0.749 8.651 1.00 20.77 ? 158 LYS A CA 1 ATOM 1201 C C . LYS A 1 158 ? -21.663 -0.366 7.237 1.00 22.88 ? 158 LYS A C 1 ATOM 1202 O O . LYS A 1 158 ? -22.333 -1.165 6.555 1.00 24.11 ? 158 LYS A O 1 ATOM 1203 C CB . LYS A 1 158 ? -22.111 -0.204 9.761 1.00 19.33 ? 158 LYS A CB 1 ATOM 1204 C CG . LYS A 1 158 ? -23.503 -0.772 9.720 1.00 17.10 ? 158 LYS A CG 1 ATOM 1205 C CD . LYS A 1 158 ? -24.395 -0.251 10.766 1.00 12.66 ? 158 LYS A CD 1 ATOM 1206 C CE . LYS A 1 158 ? -25.671 -1.108 10.879 1.00 12.71 ? 158 LYS A CE 1 ATOM 1207 N NZ . LYS A 1 158 ? -26.808 -0.339 11.577 1.00 14.36 ? 158 LYS A NZ 1 ATOM 1208 N N . LEU A 1 159 ? -21.298 0.826 6.777 1.00 24.22 ? 159 LEU A N 1 ATOM 1209 C CA . LEU A 1 159 ? -21.628 1.239 5.431 1.00 25.50 ? 159 LEU A CA 1 ATOM 1210 C C . LEU A 1 159 ? -20.919 0.422 4.352 1.00 26.15 ? 159 LEU A C 1 ATOM 1211 O O . LEU A 1 159 ? -21.399 0.348 3.216 1.00 26.63 ? 159 LEU A O 1 ATOM 1212 C CB . LEU A 1 159 ? -21.296 2.714 5.216 1.00 26.40 ? 159 LEU A CB 1 ATOM 1213 C CG . LEU A 1 159 ? -22.201 3.850 5.719 1.00 28.53 ? 159 LEU A CG 1 ATOM 1214 C CD1 . LEU A 1 159 ? -21.469 5.196 5.488 1.00 29.92 ? 159 LEU A CD1 1 ATOM 1215 C CD2 . LEU A 1 159 ? -23.623 3.839 5.120 1.00 26.89 ? 159 LEU A CD2 1 ATOM 1216 N N . LYS A 1 160 ? -19.776 -0.175 4.650 1.00 26.08 ? 160 LYS A N 1 ATOM 1217 C CA . LYS A 1 160 ? -19.128 -0.940 3.592 1.00 27.00 ? 160 LYS A CA 1 ATOM 1218 C C . LYS A 1 160 ? -19.518 -2.409 3.620 1.00 26.94 ? 160 LYS A C 1 ATOM 1219 O O . LYS A 1 160 ? -18.958 -3.240 2.903 1.00 26.20 ? 160 LYS A O 1 ATOM 1220 C CB . LYS A 1 160 ? -17.613 -0.757 3.611 1.00 27.57 ? 160 LYS A CB 1 ATOM 1221 C CG . LYS A 1 160 ? -17.202 0.642 3.138 1.00 30.86 ? 160 LYS A CG 1 ATOM 1222 C CD . LYS A 1 160 ? -15.709 0.730 2.691 1.00 37.44 ? 160 LYS A CD 1 ATOM 1223 C CE . LYS A 1 160 ? -14.753 0.990 3.911 1.00 39.62 ? 160 LYS A CE 1 ATOM 1224 N NZ . LYS A 1 160 ? -14.430 -0.265 4.679 1.00 38.49 ? 160 LYS A NZ 1 ATOM 1225 N N . ASP A 1 161 ? -20.501 -2.730 4.451 1.00 26.76 ? 161 ASP A N 1 ATOM 1226 C CA . ASP A 1 161 ? -20.774 -4.110 4.714 1.00 26.47 ? 161 ASP A CA 1 ATOM 1227 C C . ASP A 1 161 ? -22.068 -4.547 3.992 1.00 27.13 ? 161 ASP A C 1 ATOM 1228 O O . ASP A 1 161 ? -23.194 -4.116 4.358 1.00 26.89 ? 161 ASP A O 1 ATOM 1229 C CB . ASP A 1 161 ? -20.799 -4.347 6.223 1.00 26.05 ? 161 ASP A CB 1 ATOM 1230 C CG . ASP A 1 161 ? -21.300 -5.731 6.584 1.00 24.44 ? 161 ASP A CG 1 ATOM 1231 O OD1 . ASP A 1 161 ? -21.328 -6.615 5.690 1.00 26.66 ? 161 ASP A OD1 1 ATOM 1232 O OD2 . ASP A 1 161 ? -21.693 -5.938 7.743 1.00 19.61 ? 161 ASP A OD2 1 ATOM 1233 N N . PRO A 1 162 ? -21.910 -5.421 2.977 1.00 27.06 ? 162 PRO A N 1 ATOM 1234 C CA . PRO A 1 162 ? -23.022 -5.810 2.136 1.00 26.93 ? 162 PRO A CA 1 ATOM 1235 C C . PRO A 1 162 ? -24.164 -6.461 2.951 1.00 27.46 ? 162 PRO A C 1 ATOM 1236 O O . PRO A 1 162 ? -25.318 -6.419 2.538 1.00 25.64 ? 162 PRO A O 1 ATOM 1237 C CB . PRO A 1 162 ? -22.377 -6.809 1.156 1.00 27.42 ? 162 PRO A CB 1 ATOM 1238 C CG . PRO A 1 162 ? -21.190 -7.362 1.870 1.00 26.38 ? 162 PRO A CG 1 ATOM 1239 C CD . PRO A 1 162 ? -20.682 -6.183 2.646 1.00 27.45 ? 162 PRO A CD 1 ATOM 1240 N N . ARG A 1 163 ? -23.845 -7.023 4.120 1.00 28.71 ? 163 ARG A N 1 ATOM 1241 C CA . ARG A 1 163 ? -24.884 -7.693 4.926 1.00 29.37 ? 163 ARG A CA 1 ATOM 1242 C C . ARG A 1 163 ? -25.603 -6.798 5.929 1.00 28.88 ? 163 ARG A C 1 ATOM 1243 O O . ARG A 1 163 ? -26.496 -7.253 6.634 1.00 28.55 ? 163 ARG A O 1 ATOM 1244 C CB . ARG A 1 163 ? -24.366 -8.977 5.567 1.00 29.84 ? 163 ARG A CB 1 ATOM 1245 C CG . ARG A 1 163 ? -23.709 -9.876 4.550 1.00 32.23 ? 163 ARG A CG 1 ATOM 1246 C CD . ARG A 1 163 ? -22.796 -10.892 5.172 1.00 36.04 ? 163 ARG A CD 1 ATOM 1247 N NE . ARG A 1 163 ? -21.539 -10.937 4.429 1.00 41.20 ? 163 ARG A NE 1 ATOM 1248 C CZ . ARG A 1 163 ? -21.357 -11.504 3.239 1.00 41.33 ? 163 ARG A CZ 1 ATOM 1249 N NH1 . ARG A 1 163 ? -22.350 -12.106 2.619 1.00 42.23 ? 163 ARG A NH1 1 ATOM 1250 N NH2 . ARG A 1 163 ? -20.163 -11.457 2.673 1.00 41.46 ? 163 ARG A NH2 1 ATOM 1251 N N . ALA A 1 164 ? -25.266 -5.515 5.944 1.00 28.73 ? 164 ALA A N 1 ATOM 1252 C CA . ALA A 1 164 ? -25.906 -4.582 6.880 1.00 29.39 ? 164 ALA A CA 1 ATOM 1253 C C . ALA A 1 164 ? -27.380 -4.292 6.567 1.00 29.85 ? 164 ALA A C 1 ATOM 1254 O O . ALA A 1 164 ? -27.749 -4.238 5.399 1.00 30.91 ? 164 ALA A O 1 ATOM 1255 C CB . ALA A 1 164 ? -25.129 -3.278 6.940 1.00 28.92 ? 164 ALA A CB 1 ATOM 1256 N N . GLN A 1 165 ? -28.206 -4.089 7.603 1.00 29.80 ? 165 GLN A N 1 ATOM 1257 C CA . GLN A 1 165 ? -29.521 -3.477 7.451 1.00 30.38 ? 165 GLN A CA 1 ATOM 1258 C C . GLN A 1 165 ? -29.330 -1.959 7.518 1.00 31.72 ? 165 GLN A C 1 ATOM 1259 O O . GLN A 1 165 ? -29.139 -1.404 8.601 1.00 32.00 ? 165 GLN A O 1 ATOM 1260 C CB . GLN A 1 165 ? -30.520 -3.976 8.519 1.00 30.08 ? 165 GLN A CB 1 ATOM 1261 C CG . GLN A 1 165 ? -31.884 -3.282 8.453 1.00 28.57 ? 165 GLN A CG 1 ATOM 1262 C CD . GLN A 1 165 ? -32.924 -3.888 9.372 1.00 29.74 ? 165 GLN A CD 1 ATOM 1263 O OE1 . GLN A 1 165 ? -32.818 -5.036 9.825 1.00 31.74 ? 165 GLN A OE1 1 ATOM 1264 N NE2 . GLN A 1 165 ? -33.958 -3.121 9.643 1.00 28.99 ? 165 GLN A NE2 1 ATOM 1265 N N . PRO A 1 166 ? -29.373 -1.275 6.351 1.00 32.88 ? 166 PRO A N 1 ATOM 1266 C CA . PRO A 1 166 ? -29.055 0.149 6.264 1.00 33.00 ? 166 PRO A CA 1 ATOM 1267 C C . PRO A 1 166 ? -30.252 1.011 6.652 1.00 33.32 ? 166 PRO A C 1 ATOM 1268 O O . PRO A 1 166 ? -31.368 0.488 6.816 1.00 32.84 ? 166 PRO A O 1 ATOM 1269 C CB . PRO A 1 166 ? -28.725 0.326 4.793 1.00 33.40 ? 166 PRO A CB 1 ATOM 1270 C CG . PRO A 1 166 ? -29.661 -0.632 4.114 1.00 33.48 ? 166 PRO A CG 1 ATOM 1271 C CD . PRO A 1 166 ? -29.800 -1.809 5.044 1.00 33.15 ? 166 PRO A CD 1 ATOM 1272 N N . GLY A 1 167 ? -30.006 2.308 6.842 1.00 33.45 ? 167 GLY A N 1 ATOM 1273 C CA . GLY A 1 167 ? -31.043 3.212 7.305 1.00 33.85 ? 167 GLY A CA 1 ATOM 1274 C C . GLY A 1 167 ? -31.624 2.972 8.693 1.00 34.02 ? 167 GLY A C 1 ATOM 1275 O O . GLY A 1 167 ? -32.795 3.321 8.949 1.00 34.46 ? 167 GLY A O 1 ATOM 1276 N N . GLN A 1 168 ? -30.820 2.381 9.587 1.00 33.34 ? 168 GLN A N 1 ATOM 1277 C CA . GLN A 1 168 ? -31.157 2.291 11.005 1.00 32.19 ? 168 GLN A CA 1 ATOM 1278 C C . GLN A 1 168 ? -30.655 3.583 11.652 1.00 31.33 ? 168 GLN A C 1 ATOM 1279 O O . GLN A 1 168 ? -29.865 4.314 11.034 1.00 31.70 ? 168 GLN A O 1 ATOM 1280 C CB . GLN A 1 168 ? -30.490 1.085 11.624 1.00 32.28 ? 168 GLN A CB 1 ATOM 1281 C CG . GLN A 1 168 ? -31.177 -0.220 11.282 1.00 33.09 ? 168 GLN A CG 1 ATOM 1282 C CD . GLN A 1 168 ? -30.509 -1.382 11.941 1.00 33.53 ? 168 GLN A CD 1 ATOM 1283 O OE1 . GLN A 1 168 ? -29.295 -1.566 11.829 1.00 31.47 ? 168 GLN A OE1 1 ATOM 1284 N NE2 . GLN A 1 168 ? -31.296 -2.194 12.630 1.00 33.49 ? 168 GLN A NE2 1 ATOM 1285 N N . SER A 1 169 ? -31.092 3.908 12.865 1.00 29.96 ? 169 SER A N 1 ATOM 1286 C CA . SER A 1 169 ? -30.521 5.113 13.479 1.00 29.08 ? 169 SER A CA 1 ATOM 1287 C C . SER A 1 169 ? -28.999 4.933 13.699 1.00 28.34 ? 169 SER A C 1 ATOM 1288 O O . SER A 1 169 ? -28.477 3.824 13.843 1.00 28.12 ? 169 SER A O 1 ATOM 1289 C CB . SER A 1 169 ? -31.241 5.539 14.743 1.00 27.98 ? 169 SER A CB 1 ATOM 1290 O OG . SER A 1 169 ? -31.356 4.445 15.580 1.00 28.83 ? 169 SER A OG 1 ATOM 1291 N N . SER A 1 170 ? -28.290 6.039 13.625 1.00 28.05 ? 170 SER A N 1 ATOM 1292 C CA . SER A 1 170 ? -26.922 6.111 14.104 1.00 28.35 ? 170 SER A CA 1 ATOM 1293 C C . SER A 1 170 ? -26.729 5.452 15.474 1.00 26.31 ? 170 SER A C 1 ATOM 1294 O O . SER A 1 170 ? -27.589 5.535 16.351 1.00 25.28 ? 170 SER A O 1 ATOM 1295 C CB . SER A 1 170 ? -26.502 7.588 14.235 1.00 28.98 ? 170 SER A CB 1 ATOM 1296 O OG . SER A 1 170 ? -25.762 7.987 13.097 1.00 33.87 ? 170 SER A OG 1 ATOM 1297 N N . PRO A 1 171 ? -25.584 4.806 15.657 1.00 25.61 ? 171 PRO A N 1 ATOM 1298 C CA . PRO A 1 171 ? -25.114 4.646 17.031 1.00 25.34 ? 171 PRO A CA 1 ATOM 1299 C C . PRO A 1 171 ? -24.628 6.021 17.540 1.00 25.20 ? 171 PRO A C 1 ATOM 1300 O O . PRO A 1 171 ? -24.093 6.811 16.767 1.00 25.44 ? 171 PRO A O 1 ATOM 1301 C CB . PRO A 1 171 ? -23.966 3.661 16.887 1.00 25.30 ? 171 PRO A CB 1 ATOM 1302 C CG . PRO A 1 171 ? -23.510 3.810 15.493 1.00 25.25 ? 171 PRO A CG 1 ATOM 1303 C CD . PRO A 1 171 ? -24.651 4.259 14.662 1.00 24.96 ? 171 PRO A CD 1 ATOM 1304 N N . LYS A 1 172 ? -24.838 6.325 18.816 1.00 25.58 ? 172 LYS A N 1 ATOM 1305 C CA . LYS A 1 172 ? -24.449 7.631 19.373 1.00 24.84 ? 172 LYS A CA 1 ATOM 1306 C C . LYS A 1 172 ? -24.082 7.413 20.830 1.00 24.90 ? 172 LYS A C 1 ATOM 1307 O O . LYS A 1 172 ? -24.249 6.300 21.343 1.00 25.46 ? 172 LYS A O 1 ATOM 1308 C CB . LYS A 1 172 ? -25.629 8.579 19.285 1.00 24.87 ? 172 LYS A CB 1 ATOM 1309 C CG . LYS A 1 172 ? -26.846 8.044 20.027 1.00 25.99 ? 172 LYS A CG 1 ATOM 1310 C CD . LYS A 1 172 ? -28.062 8.914 19.918 1.00 24.31 ? 172 LYS A CD 1 ATOM 1311 C CE . LYS A 1 172 ? -29.275 8.046 20.088 1.00 25.47 ? 172 LYS A CE 1 ATOM 1312 N NZ . LYS A 1 172 ? -30.365 8.956 20.333 1.00 29.63 ? 172 LYS A NZ 1 ATOM 1313 N N . ILE A 1 173 ? -23.586 8.457 21.507 1.00 24.15 ? 173 ILE A N 1 ATOM 1314 C CA . ILE A 1 173 ? -23.430 8.376 22.950 1.00 22.82 ? 173 ILE A CA 1 ATOM 1315 C C . ILE A 1 173 ? -24.752 8.621 23.718 1.00 23.81 ? 173 ILE A C 1 ATOM 1316 O O . ILE A 1 173 ? -25.186 9.749 23.939 1.00 24.31 ? 173 ILE A O 1 ATOM 1317 C CB . ILE A 1 173 ? -22.318 9.262 23.475 1.00 21.98 ? 173 ILE A CB 1 ATOM 1318 C CG1 . ILE A 1 173 ? -21.023 8.923 22.776 1.00 18.97 ? 173 ILE A CG1 1 ATOM 1319 C CG2 . ILE A 1 173 ? -22.120 8.977 24.948 1.00 21.28 ? 173 ILE A CG2 1 ATOM 1320 C CD1 . ILE A 1 173 ? -19.936 9.895 23.087 1.00 18.94 ? 173 ILE A CD1 1 ATOM 1321 N N . ASP A 1 174 ? -25.367 7.538 24.137 1.00 24.11 ? 174 ASP A N 1 ATOM 1322 C CA . ASP A 1 174 ? -26.708 7.593 24.669 1.00 25.13 ? 174 ASP A CA 1 ATOM 1323 C C . ASP A 1 174 ? -26.792 8.261 26.016 1.00 25.63 ? 174 ASP A C 1 ATOM 1324 O O . ASP A 1 174 ? -27.850 8.754 26.415 1.00 26.48 ? 174 ASP A O 1 ATOM 1325 C CB . ASP A 1 174 ? -27.254 6.169 24.786 1.00 25.08 ? 174 ASP A CB 1 ATOM 1326 C CG . ASP A 1 174 ? -27.446 5.516 23.428 1.00 25.98 ? 174 ASP A CG 1 ATOM 1327 O OD1 . ASP A 1 174 ? -28.486 5.780 22.804 1.00 29.06 ? 174 ASP A OD1 1 ATOM 1328 O OD2 . ASP A 1 174 ? -26.562 4.774 22.972 1.00 23.88 ? 174 ASP A OD2 1 ATOM 1329 N N . VAL A 1 175 ? -25.685 8.250 26.740 1.00 25.74 ? 175 VAL A N 1 ATOM 1330 C CA . VAL A 1 175 ? -25.695 8.696 28.114 1.00 24.87 ? 175 VAL A CA 1 ATOM 1331 C C . VAL A 1 175 ? -24.282 9.118 28.348 1.00 25.06 ? 175 VAL A C 1 ATOM 1332 O O . VAL A 1 175 ? -23.358 8.308 28.204 1.00 24.94 ? 175 VAL A O 1 ATOM 1333 C CB . VAL A 1 175 ? -26.098 7.562 29.109 1.00 24.60 ? 175 VAL A CB 1 ATOM 1334 C CG1 . VAL A 1 175 ? -25.851 7.977 30.534 1.00 23.06 ? 175 VAL A CG1 1 ATOM 1335 C CG2 . VAL A 1 175 ? -27.558 7.154 28.943 1.00 24.69 ? 175 VAL A CG2 1 ATOM 1336 N N . VAL A 1 176 ? -24.108 10.403 28.643 1.00 25.71 ? 176 VAL A N 1 ATOM 1337 C CA . VAL A 1 176 ? -22.841 10.913 29.196 1.00 25.72 ? 176 VAL A CA 1 ATOM 1338 C C . VAL A 1 176 ? -23.005 10.876 30.707 1.00 25.94 ? 176 VAL A C 1 ATOM 1339 O O . VAL A 1 176 ? -23.919 11.537 31.243 1.00 26.44 ? 176 VAL A O 1 ATOM 1340 C CB . VAL A 1 176 ? -22.572 12.340 28.770 1.00 25.83 ? 176 VAL A CB 1 ATOM 1341 C CG1 . VAL A 1 176 ? -21.259 12.844 29.389 1.00 27.27 ? 176 VAL A CG1 1 ATOM 1342 C CG2 . VAL A 1 176 ? -22.501 12.423 27.262 1.00 25.24 ? 176 VAL A CG2 1 ATOM 1343 N N . ILE A 1 177 ? -22.173 10.075 31.387 1.00 24.85 ? 177 ILE A N 1 ATOM 1344 C CA . ILE A 1 177 ? -22.223 10.006 32.855 1.00 23.76 ? 177 ILE A CA 1 ATOM 1345 C C . ILE A 1 177 ? -21.265 11.029 33.464 1.00 23.50 ? 177 ILE A C 1 ATOM 1346 O O . ILE A 1 177 ? -20.079 11.006 33.181 1.00 23.51 ? 177 ILE A O 1 ATOM 1347 C CB . ILE A 1 177 ? -21.821 8.616 33.430 1.00 23.30 ? 177 ILE A CB 1 ATOM 1348 C CG1 . ILE A 1 177 ? -22.603 7.495 32.773 1.00 21.48 ? 177 ILE A CG1 1 ATOM 1349 C CG2 . ILE A 1 177 ? -22.036 8.599 34.928 1.00 21.46 ? 177 ILE A CG2 1 ATOM 1350 C CD1 . ILE A 1 177 ? -22.383 6.135 33.431 1.00 21.49 ? 177 ILE A CD1 1 ATOM 1351 N N . SER A 1 178 ? -21.791 11.868 34.338 1.00 23.38 ? 178 SER A N 1 ATOM 1352 C CA . SER A 1 178 ? -21.035 12.908 34.991 1.00 23.97 ? 178 SER A CA 1 ATOM 1353 C C . SER A 1 178 ? -19.883 12.448 35.909 1.00 24.40 ? 178 SER A C 1 ATOM 1354 O O . SER A 1 178 ? -20.027 11.470 36.667 1.00 23.66 ? 178 SER A O 1 ATOM 1355 C CB . SER A 1 178 ? -21.981 13.804 35.804 1.00 23.47 ? 178 SER A CB 1 ATOM 1356 O OG . SER A 1 178 ? -21.209 14.842 36.382 1.00 24.68 ? 178 SER A OG 1 ATOM 1357 N N . GLU A 1 179 ? -18.779 13.205 35.857 1.00 24.30 ? 179 GLU A N 1 ATOM 1358 C CA . GLU A 1 179 ? -17.658 13.062 36.786 1.00 24.98 ? 179 GLU A CA 1 ATOM 1359 C C . GLU A 1 179 ? -17.670 14.031 37.982 1.00 25.36 ? 179 GLU A C 1 ATOM 1360 O O . GLU A 1 179 ? -16.727 14.025 38.776 1.00 24.70 ? 179 GLU A O 1 ATOM 1361 C CB . GLU A 1 179 ? -16.317 13.199 36.036 1.00 25.45 ? 179 GLU A CB 1 ATOM 1362 C CG . GLU A 1 179 ? -16.197 12.204 34.889 1.00 27.38 ? 179 GLU A CG 1 ATOM 1363 C CD . GLU A 1 179 ? -14.805 12.067 34.266 1.00 30.02 ? 179 GLU A CD 1 ATOM 1364 O OE1 . GLU A 1 179 ? -13.917 12.927 34.489 1.00 30.24 ? 179 GLU A OE1 1 ATOM 1365 O OE2 . GLU A 1 179 ? -14.615 11.073 33.526 1.00 32.49 ? 179 GLU A OE2 1 ATOM 1366 N N . ALA A 1 180 ? -18.711 14.872 38.127 1.00 26.21 ? 180 ALA A N 1 ATOM 1367 C CA . ALA A 1 180 ? -18.767 15.790 39.287 1.00 26.51 ? 180 ALA A CA 1 ATOM 1368 C C . ALA A 1 180 ? -18.652 14.954 40.542 1.00 27.54 ? 180 ALA A C 1 ATOM 1369 O O . ALA A 1 180 ? -19.077 13.775 40.596 1.00 27.31 ? 180 ALA A O 1 ATOM 1370 C CB . ALA A 1 180 ? -20.015 16.631 39.327 1.00 25.99 ? 180 ALA A CB 1 ATOM 1371 N N . SER A 1 181 ? -18.051 15.579 41.547 1.00 28.26 ? 181 SER A N 1 ATOM 1372 C CA . SER A 1 181 ? -17.660 14.899 42.767 1.00 28.42 ? 181 SER A CA 1 ATOM 1373 C C . SER A 1 181 ? -18.851 14.247 43.441 1.00 27.74 ? 181 SER A C 1 ATOM 1374 O O . SER A 1 181 ? -18.655 13.336 44.230 1.00 28.66 ? 181 SER A O 1 ATOM 1375 C CB . SER A 1 181 ? -16.934 15.868 43.724 1.00 28.66 ? 181 SER A CB 1 ATOM 1376 O OG . SER A 1 181 ? -17.542 17.166 43.667 1.00 29.43 ? 181 SER A OG 1 ATOM 1377 N N . SER A 1 182 ? -20.069 14.699 43.135 1.00 27.19 ? 182 SER A N 1 ATOM 1378 C CA . SER A 1 182 ? -21.270 14.102 43.735 1.00 26.78 ? 182 SER A CA 1 ATOM 1379 C C . SER A 1 182 ? -22.066 13.143 42.811 1.00 26.07 ? 182 SER A C 1 ATOM 1380 O O . SER A 1 182 ? -23.176 12.674 43.187 1.00 26.14 ? 182 SER A O 1 ATOM 1381 C CB . SER A 1 182 ? -22.205 15.187 44.194 1.00 27.25 ? 182 SER A CB 1 ATOM 1382 O OG . SER A 1 182 ? -22.847 15.748 43.069 1.00 28.79 ? 182 SER A OG 1 ATOM 1383 N N . SER A 1 183 ? -21.527 12.874 41.618 1.00 24.25 ? 183 SER A N 1 ATOM 1384 C CA . SER A 1 183 ? -22.182 11.984 40.667 1.00 23.17 ? 183 SER A CA 1 ATOM 1385 C C . SER A 1 183 ? -21.881 10.507 40.947 1.00 22.29 ? 183 SER A C 1 ATOM 1386 O O . SER A 1 183 ? -20.715 10.085 40.990 1.00 22.77 ? 183 SER A O 1 ATOM 1387 C CB . SER A 1 183 ? -21.737 12.333 39.243 1.00 24.06 ? 183 SER A CB 1 ATOM 1388 O OG . SER A 1 183 ? -22.300 11.465 38.262 1.00 22.28 ? 183 SER A OG 1 ATOM 1389 N N . ASN A 1 184 ? -22.927 9.717 41.144 1.00 20.44 ? 184 ASN A N 1 ATOM 1390 C CA . ASN A 1 184 ? -22.766 8.272 41.146 1.00 18.98 ? 184 ASN A CA 1 ATOM 1391 C C . ASN A 1 184 ? -22.369 7.860 39.741 1.00 17.78 ? 184 ASN A C 1 ATOM 1392 O O . ASN A 1 184 ? -23.187 7.862 38.871 1.00 18.14 ? 184 ASN A O 1 ATOM 1393 C CB . ASN A 1 184 ? -24.058 7.565 41.646 1.00 19.12 ? 184 ASN A CB 1 ATOM 1394 C CG . ASN A 1 184 ? -24.377 7.890 43.115 1.00 19.34 ? 184 ASN A CG 1 ATOM 1395 O OD1 . ASN A 1 184 ? -23.555 8.486 43.810 1.00 21.99 ? 184 ASN A OD1 1 ATOM 1396 N ND2 . ASN A 1 184 ? -25.561 7.484 43.597 1.00 19.96 ? 184 ASN A ND2 1 ATOM 1397 N N . ASN A 1 185 ? -21.103 7.530 39.531 1.00 17.33 ? 185 ASN A N 1 ATOM 1398 C CA . ASN A 1 185 ? -20.542 7.218 38.214 1.00 16.83 ? 185 ASN A CA 1 ATOM 1399 C C . ASN A 1 185 ? -19.877 5.818 38.173 1.00 17.00 ? 185 ASN A C 1 ATOM 1400 O O . ASN A 1 185 ? -18.773 5.664 38.714 1.00 16.61 ? 185 ASN A O 1 ATOM 1401 C CB . ASN A 1 185 ? -19.480 8.260 37.864 1.00 15.94 ? 185 ASN A CB 1 ATOM 1402 C CG . ASN A 1 185 ? -18.778 7.986 36.507 1.00 17.36 ? 185 ASN A CG 1 ATOM 1403 O OD1 . ASN A 1 185 ? -18.211 8.893 35.899 1.00 18.24 ? 185 ASN A OD1 1 ATOM 1404 N ND2 . ASN A 1 185 ? -18.856 6.763 36.022 1.00 19.00 ? 185 ASN A ND2 1 ATOM 1405 N N . THR A 1 186 ? -20.490 4.821 37.515 1.00 16.69 ? 186 THR A N 1 ATOM 1406 C CA . THR A 1 186 ? -20.011 3.438 37.675 1.00 17.38 ? 186 THR A CA 1 ATOM 1407 C C . THR A 1 186 ? -18.779 3.135 36.843 1.00 18.15 ? 186 THR A C 1 ATOM 1408 O O . THR A 1 186 ? -18.133 2.099 37.035 1.00 18.27 ? 186 THR A O 1 ATOM 1409 C CB . THR A 1 186 ? -21.042 2.354 37.318 1.00 17.04 ? 186 THR A CB 1 ATOM 1410 O OG1 . THR A 1 186 ? -21.410 2.468 35.924 1.00 19.10 ? 186 THR A OG1 1 ATOM 1411 C CG2 . THR A 1 186 ? -22.266 2.436 38.189 1.00 15.84 ? 186 THR A CG2 1 ATOM 1412 N N . LEU A 1 187 ? -18.497 4.019 35.900 1.00 19.14 ? 187 LEU A N 1 ATOM 1413 C CA . LEU A 1 187 ? -17.394 3.895 34.957 1.00 20.40 ? 187 LEU A CA 1 ATOM 1414 C C . LEU A 1 187 ? -16.094 4.271 35.636 1.00 20.86 ? 187 LEU A C 1 ATOM 1415 O O . LEU A 1 187 ? -15.007 3.816 35.208 1.00 20.76 ? 187 LEU A O 1 ATOM 1416 C CB . LEU A 1 187 ? -17.617 4.799 33.708 1.00 19.95 ? 187 LEU A CB 1 ATOM 1417 C CG . LEU A 1 187 ? -18.882 4.504 32.861 1.00 21.15 ? 187 LEU A CG 1 ATOM 1418 C CD1 . LEU A 1 187 ? -19.039 5.372 31.591 1.00 18.17 ? 187 LEU A CD1 1 ATOM 1419 C CD2 . LEU A 1 187 ? -18.977 3.041 32.474 1.00 18.32 ? 187 LEU A CD2 1 ATOM 1420 N N . ASP A 1 188 ? -16.193 5.117 36.671 1.00 21.10 ? 188 ASP A N 1 ATOM 1421 C CA . ASP A 1 188 ? -14.986 5.596 37.404 1.00 22.43 ? 188 ASP A CA 1 ATOM 1422 C C . ASP A 1 188 ? -15.439 6.391 38.636 1.00 21.54 ? 188 ASP A C 1 ATOM 1423 O O . ASP A 1 188 ? -15.442 7.634 38.620 1.00 21.14 ? 188 ASP A O 1 ATOM 1424 C CB . ASP A 1 188 ? -14.053 6.390 36.477 1.00 22.91 ? 188 ASP A CB 1 ATOM 1425 C CG . ASP A 1 188 ? -12.771 6.883 37.175 1.00 27.62 ? 188 ASP A CG 1 ATOM 1426 O OD1 . ASP A 1 188 ? -11.691 6.247 37.055 1.00 30.03 ? 188 ASP A OD1 1 ATOM 1427 O OD2 . ASP A 1 188 ? -12.828 7.958 37.807 1.00 35.74 ? 188 ASP A OD2 1 ATOM 1428 N N . PRO A 1 189 ? -15.878 5.660 39.685 1.00 20.85 ? 189 PRO A N 1 ATOM 1429 C CA . PRO A 1 189 ? -16.619 6.261 40.787 1.00 20.73 ? 189 PRO A CA 1 ATOM 1430 C C . PRO A 1 189 ? -15.792 7.272 41.549 1.00 21.11 ? 189 PRO A C 1 ATOM 1431 O O . PRO A 1 189 ? -14.563 7.119 41.679 1.00 19.73 ? 189 PRO A O 1 ATOM 1432 C CB . PRO A 1 189 ? -16.960 5.064 41.678 1.00 20.16 ? 189 PRO A CB 1 ATOM 1433 C CG . PRO A 1 189 ? -16.822 3.894 40.822 1.00 19.44 ? 189 PRO A CG 1 ATOM 1434 C CD . PRO A 1 189 ? -15.752 4.198 39.865 1.00 20.04 ? 189 PRO A CD 1 ATOM 1435 N N . GLY A 1 190 ? -16.466 8.303 42.042 1.00 21.59 ? 190 GLY A N 1 ATOM 1436 C CA . GLY A 1 190 ? -15.748 9.381 42.700 1.00 23.38 ? 190 GLY A CA 1 ATOM 1437 C C . GLY A 1 190 ? -16.271 9.695 44.081 1.00 24.21 ? 190 GLY A C 1 ATOM 1438 O O . GLY A 1 190 ? -15.920 10.733 44.656 1.00 24.54 ? 190 GLY A O 1 ATOM 1439 N N . THR A 1 191 ? -17.109 8.810 44.611 1.00 24.70 ? 191 THR A N 1 ATOM 1440 C CA . THR A 1 191 ? -17.855 9.142 45.823 1.00 25.88 ? 191 THR A CA 1 ATOM 1441 C C . THR A 1 191 ? -17.389 8.420 47.068 1.00 25.98 ? 191 THR A C 1 ATOM 1442 O O . THR A 1 191 ? -17.869 8.714 48.129 1.00 26.73 ? 191 THR A O 1 ATOM 1443 C CB . THR A 1 191 ? -19.393 8.936 45.658 1.00 25.82 ? 191 THR A CB 1 ATOM 1444 O OG1 . THR A 1 191 ? -19.662 7.798 44.817 1.00 26.09 ? 191 THR A OG1 1 ATOM 1445 C CG2 . THR A 1 191 ? -20.004 10.139 45.044 1.00 26.09 ? 191 THR A CG2 1 ATOM 1446 N N . CYS A 1 192 ? -16.480 7.470 46.934 1.00 26.46 ? 192 CYS A N 1 ATOM 1447 C CA . CYS A 1 192 ? -16.016 6.680 48.068 1.00 27.52 ? 192 CYS A CA 1 ATOM 1448 C C . CYS A 1 192 ? -14.938 7.452 48.825 1.00 27.98 ? 192 CYS A C 1 ATOM 1449 O O . CYS A 1 192 ? -13.739 7.280 48.589 1.00 27.65 ? 192 CYS A O 1 ATOM 1450 C CB . CYS A 1 192 ? -15.466 5.352 47.566 1.00 27.68 ? 192 CYS A CB 1 ATOM 1451 S SG . CYS A 1 192 ? -15.011 4.142 48.806 1.00 30.02 ? 192 CYS A SG 1 ATOM 1452 N N . THR A 1 193 ? -15.383 8.312 49.732 1.00 28.58 ? 193 THR A N 1 ATOM 1453 C CA . THR A 1 193 ? -14.513 9.264 50.465 1.00 29.33 ? 193 THR A CA 1 ATOM 1454 C C . THR A 1 193 ? -13.186 8.670 51.001 1.00 28.35 ? 193 THR A C 1 ATOM 1455 O O . THR A 1 193 ? -12.119 9.221 50.783 1.00 28.28 ? 193 THR A O 1 ATOM 1456 C CB . THR A 1 193 ? -15.301 9.872 51.662 1.00 29.94 ? 193 THR A CB 1 ATOM 1457 O OG1 . THR A 1 193 ? -16.684 10.034 51.301 1.00 30.73 ? 193 THR A OG1 1 ATOM 1458 C CG2 . THR A 1 193 ? -14.700 11.205 52.096 1.00 31.92 ? 193 THR A CG2 1 ATOM 1459 N N . VAL A 1 194 ? -13.265 7.538 51.699 1.00 28.21 ? 194 VAL A N 1 ATOM 1460 C CA . VAL A 1 194 ? -12.081 6.923 52.292 1.00 27.34 ? 194 VAL A CA 1 ATOM 1461 C C . VAL A 1 194 ? -11.089 6.511 51.181 1.00 28.06 ? 194 VAL A C 1 ATOM 1462 O O . VAL A 1 194 ? -9.866 6.736 51.329 1.00 28.10 ? 194 VAL A O 1 ATOM 1463 C CB . VAL A 1 194 ? -12.429 5.783 53.288 1.00 27.08 ? 194 VAL A CB 1 ATOM 1464 C CG1 . VAL A 1 194 ? -11.160 5.096 53.808 1.00 26.72 ? 194 VAL A CG1 1 ATOM 1465 C CG2 . VAL A 1 194 ? -13.275 6.334 54.472 1.00 26.24 ? 194 VAL A CG2 1 ATOM 1466 N N . PHE A 1 195 ? -11.615 5.964 50.065 1.00 27.38 ? 195 PHE A N 1 ATOM 1467 C CA . PHE A 1 195 ? -10.777 5.580 48.918 1.00 26.63 ? 195 PHE A CA 1 ATOM 1468 C C . PHE A 1 195 ? -10.162 6.804 48.232 1.00 27.97 ? 195 PHE A C 1 ATOM 1469 O O . PHE A 1 195 ? -8.985 6.812 47.849 1.00 27.69 ? 195 PHE A O 1 ATOM 1470 C CB . PHE A 1 195 ? -11.544 4.712 47.897 1.00 25.85 ? 195 PHE A CB 1 ATOM 1471 C CG . PHE A 1 195 ? -10.791 4.487 46.615 1.00 20.94 ? 195 PHE A CG 1 ATOM 1472 C CD1 . PHE A 1 195 ? -9.771 3.526 46.545 1.00 19.76 ? 195 PHE A CD1 1 ATOM 1473 C CD2 . PHE A 1 195 ? -11.029 5.285 45.505 1.00 16.69 ? 195 PHE A CD2 1 ATOM 1474 C CE1 . PHE A 1 195 ? -9.020 3.327 45.343 1.00 13.89 ? 195 PHE A CE1 1 ATOM 1475 C CE2 . PHE A 1 195 ? -10.292 5.097 44.331 1.00 12.91 ? 195 PHE A CE2 1 ATOM 1476 C CZ . PHE A 1 195 ? -9.286 4.109 44.262 1.00 10.03 ? 195 PHE A CZ 1 ATOM 1477 N N . GLU A 1 196 ? -10.954 7.847 48.083 1.00 29.29 ? 196 GLU A N 1 ATOM 1478 C CA . GLU A 1 196 ? -10.435 9.053 47.450 1.00 31.26 ? 196 GLU A CA 1 ATOM 1479 C C . GLU A 1 196 ? -9.202 9.605 48.214 1.00 32.28 ? 196 GLU A C 1 ATOM 1480 O O . GLU A 1 196 ? -8.306 10.213 47.600 1.00 32.37 ? 196 GLU A O 1 ATOM 1481 C CB . GLU A 1 196 ? -11.567 10.115 47.285 1.00 31.45 ? 196 GLU A CB 1 ATOM 1482 C CG . GLU A 1 196 ? -12.591 9.815 46.129 1.00 30.85 ? 196 GLU A CG 1 ATOM 1483 C CD . GLU A 1 196 ? -11.910 9.441 44.796 1.00 32.20 ? 196 GLU A CD 1 ATOM 1484 O OE1 . GLU A 1 196 ? -10.900 10.102 44.460 1.00 31.72 ? 196 GLU A OE1 1 ATOM 1485 O OE2 . GLU A 1 196 ? -12.376 8.489 44.095 1.00 30.73 ? 196 GLU A OE2 1 ATOM 1486 N N . ASP A 1 197 ? -9.168 9.363 49.534 1.00 32.25 ? 197 ASP A N 1 ATOM 1487 C CA . ASP A 1 197 ? -8.132 9.891 50.421 1.00 32.75 ? 197 ASP A CA 1 ATOM 1488 C C . ASP A 1 197 ? -6.875 8.977 50.495 1.00 33.34 ? 197 ASP A C 1 ATOM 1489 O O . ASP A 1 197 ? -5.776 9.455 50.820 1.00 33.84 ? 197 ASP A O 1 ATOM 1490 C CB . ASP A 1 197 ? -8.715 10.100 51.837 1.00 33.19 ? 197 ASP A CB 1 ATOM 1491 C CG . ASP A 1 197 ? -9.554 11.410 51.997 1.00 32.11 ? 197 ASP A CG 1 ATOM 1492 O OD1 . ASP A 1 197 ? -9.738 12.207 51.072 1.00 32.30 ? 197 ASP A OD1 1 ATOM 1493 O OD2 . ASP A 1 197 ? -10.047 11.639 53.103 1.00 31.74 ? 197 ASP A OD2 1 ATOM 1494 N N . SER A 1 198 ? -7.039 7.683 50.192 1.00 32.96 ? 198 SER A N 1 ATOM 1495 C CA . SER A 1 198 ? -5.948 6.694 50.265 1.00 32.91 ? 198 SER A CA 1 ATOM 1496 C C . SER A 1 198 ? -4.610 7.199 49.709 1.00 33.49 ? 198 SER A C 1 ATOM 1497 O O . SER A 1 198 ? -4.579 7.900 48.697 1.00 33.60 ? 198 SER A O 1 ATOM 1498 C CB . SER A 1 198 ? -6.330 5.382 49.555 1.00 32.60 ? 198 SER A CB 1 ATOM 1499 O OG . SER A 1 198 ? -5.231 4.482 49.480 1.00 30.14 ? 198 SER A OG 1 ATOM 1500 N N . GLU A 1 199 ? -3.513 6.802 50.355 1.00 33.74 ? 199 GLU A N 1 ATOM 1501 C CA . GLU A 1 199 ? -2.171 7.206 49.934 1.00 34.28 ? 199 GLU A CA 1 ATOM 1502 C C . GLU A 1 199 ? -1.237 5.999 49.794 1.00 33.03 ? 199 GLU A C 1 ATOM 1503 O O . GLU A 1 199 ? -0.036 6.173 49.660 1.00 33.81 ? 199 GLU A O 1 ATOM 1504 C CB . GLU A 1 199 ? -1.593 8.273 50.900 1.00 35.32 ? 199 GLU A CB 1 ATOM 1505 C CG . GLU A 1 199 ? -2.504 9.537 51.076 1.00 39.32 ? 199 GLU A CG 1 ATOM 1506 C CD . GLU A 1 199 ? -1.979 10.581 52.107 1.00 46.44 ? 199 GLU A CD 1 ATOM 1507 O OE1 . GLU A 1 199 ? -1.769 10.215 53.302 1.00 47.45 ? 199 GLU A OE1 1 ATOM 1508 O OE2 . GLU A 1 199 ? -1.807 11.778 51.720 1.00 47.10 ? 199 GLU A OE2 1 ATOM 1509 N N . LEU A 1 200 ? -1.800 4.786 49.805 1.00 32.22 ? 200 LEU A N 1 ATOM 1510 C CA . LEU A 1 200 ? -1.047 3.518 49.676 1.00 30.69 ? 200 LEU A CA 1 ATOM 1511 C C . LEU A 1 200 ? -0.202 3.450 48.383 1.00 30.72 ? 200 LEU A C 1 ATOM 1512 O O . LEU A 1 200 ? 0.988 3.110 48.428 1.00 30.60 ? 200 LEU A O 1 ATOM 1513 C CB . LEU A 1 200 ? -1.986 2.317 49.811 1.00 30.17 ? 200 LEU A CB 1 ATOM 1514 C CG . LEU A 1 200 ? -1.504 0.861 49.679 1.00 30.60 ? 200 LEU A CG 1 ATOM 1515 C CD1 . LEU A 1 200 ? -0.309 0.473 50.615 1.00 28.57 ? 200 LEU A CD1 1 ATOM 1516 C CD2 . LEU A 1 200 ? -2.674 -0.042 49.948 1.00 27.75 ? 200 LEU A CD2 1 ATOM 1517 N N . ALA A 1 201 ? -0.801 3.827 47.255 1.00 29.98 ? 201 ALA A N 1 ATOM 1518 C CA . ALA A 1 201 ? -0.097 3.880 45.964 1.00 30.01 ? 201 ALA A CA 1 ATOM 1519 C C . ALA A 1 201 ? 1.195 4.706 45.979 1.00 29.91 ? 201 ALA A C 1 ATOM 1520 O O . ALA A 1 201 ? 2.246 4.206 45.574 1.00 28.97 ? 201 ALA A O 1 ATOM 1521 C CB . ALA A 1 201 ? -1.052 4.345 44.818 1.00 29.63 ? 201 ALA A CB 1 ATOM 1522 N N . ASP A 1 202 ? 1.096 5.962 46.436 1.00 30.62 ? 202 ASP A N 1 ATOM 1523 C CA . ASP A 1 202 ? 2.252 6.831 46.679 1.00 31.28 ? 202 ASP A CA 1 ATOM 1524 C C . ASP A 1 202 ? 3.341 6.136 47.486 1.00 31.37 ? 202 ASP A C 1 ATOM 1525 O O . ASP A 1 202 ? 4.531 6.156 47.123 1.00 31.07 ? 202 ASP A O 1 ATOM 1526 C CB . ASP A 1 202 ? 1.835 8.083 47.426 1.00 31.77 ? 202 ASP A CB 1 ATOM 1527 C CG . ASP A 1 202 ? 1.092 9.072 46.549 1.00 34.54 ? 202 ASP A CG 1 ATOM 1528 O OD1 . ASP A 1 202 ? 1.269 9.027 45.315 1.00 37.49 ? 202 ASP A OD1 1 ATOM 1529 O OD2 . ASP A 1 202 ? 0.331 9.910 47.098 1.00 38.54 ? 202 ASP A OD2 1 ATOM 1530 N N . THR A 1 203 ? 2.949 5.507 48.584 1.00 31.58 ? 203 THR A N 1 ATOM 1531 C CA . THR A 1 203 ? 3.961 4.873 49.406 1.00 31.43 ? 203 THR A CA 1 ATOM 1532 C C . THR A 1 203 ? 4.720 3.863 48.566 1.00 31.52 ? 203 THR A C 1 ATOM 1533 O O . THR A 1 203 ? 5.952 3.980 48.430 1.00 31.99 ? 203 THR A O 1 ATOM 1534 C CB . THR A 1 203 ? 3.370 4.342 50.685 1.00 31.06 ? 203 THR A CB 1 ATOM 1535 O OG1 . THR A 1 203 ? 2.811 5.469 51.372 1.00 31.35 ? 203 THR A OG1 1 ATOM 1536 C CG2 . THR A 1 203 ? 4.458 3.756 51.577 1.00 32.03 ? 203 THR A CG2 1 ATOM 1537 N N . VAL A 1 204 ? 3.993 2.940 47.928 1.00 31.25 ? 204 VAL A N 1 ATOM 1538 C CA . VAL A 1 204 ? 4.619 1.937 47.061 1.00 30.89 ? 204 VAL A CA 1 ATOM 1539 C C . VAL A 1 204 ? 5.460 2.548 45.917 1.00 30.10 ? 204 VAL A C 1 ATOM 1540 O O . VAL A 1 204 ? 6.510 2.038 45.568 1.00 29.58 ? 204 VAL A O 1 ATOM 1541 C CB . VAL A 1 204 ? 3.587 0.994 46.452 1.00 31.22 ? 204 VAL A CB 1 ATOM 1542 C CG1 . VAL A 1 204 ? 4.310 -0.121 45.702 1.00 31.22 ? 204 VAL A CG1 1 ATOM 1543 C CG2 . VAL A 1 204 ? 2.659 0.447 47.527 1.00 30.57 ? 204 VAL A CG2 1 ATOM 1544 N N . GLU A 1 205 ? 4.975 3.641 45.346 1.00 29.84 ? 205 GLU A N 1 ATOM 1545 C CA . GLU A 1 205 ? 5.652 4.287 44.245 1.00 29.16 ? 205 GLU A CA 1 ATOM 1546 C C . GLU A 1 205 ? 7.014 4.769 44.719 1.00 29.34 ? 205 GLU A C 1 ATOM 1547 O O . GLU A 1 205 ? 8.023 4.480 44.076 1.00 29.32 ? 205 GLU A O 1 ATOM 1548 C CB . GLU A 1 205 ? 4.844 5.458 43.679 1.00 28.86 ? 205 GLU A CB 1 ATOM 1549 C CG . GLU A 1 205 ? 5.575 6.189 42.497 1.00 29.13 ? 205 GLU A CG 1 ATOM 1550 C CD . GLU A 1 205 ? 4.769 7.307 41.802 1.00 29.15 ? 205 GLU A CD 1 ATOM 1551 O OE1 . GLU A 1 205 ? 3.627 7.636 42.217 1.00 30.55 ? 205 GLU A OE1 1 ATOM 1552 O OE2 . GLU A 1 205 ? 5.286 7.848 40.810 1.00 30.78 ? 205 GLU A OE2 1 ATOM 1553 N N . ALA A 1 206 ? 7.041 5.499 45.837 1.00 29.25 ? 206 ALA A N 1 ATOM 1554 C CA . ALA A 1 206 ? 8.289 5.990 46.434 1.00 28.92 ? 206 ALA A CA 1 ATOM 1555 C C . ALA A 1 206 ? 9.189 4.837 46.843 1.00 28.82 ? 206 ALA A C 1 ATOM 1556 O O . ALA A 1 206 ? 10.363 4.794 46.455 1.00 28.47 ? 206 ALA A O 1 ATOM 1557 C CB . ALA A 1 206 ? 8.014 6.905 47.631 1.00 28.50 ? 206 ALA A CB 1 ATOM 1558 N N . ASN A 1 207 ? 8.646 3.880 47.594 1.00 29.01 ? 207 ASN A N 1 ATOM 1559 C CA . ASN A 1 207 ? 9.473 2.746 47.993 1.00 29.73 ? 207 ASN A CA 1 ATOM 1560 C C . ASN A 1 207 ? 10.127 2.014 46.811 1.00 29.54 ? 207 ASN A C 1 ATOM 1561 O O . ASN A 1 207 ? 11.339 1.777 46.833 1.00 29.70 ? 207 ASN A O 1 ATOM 1562 C CB . ASN A 1 207 ? 8.742 1.800 48.949 1.00 30.33 ? 207 ASN A CB 1 ATOM 1563 C CG . ASN A 1 207 ? 8.520 2.410 50.367 1.00 33.05 ? 207 ASN A CG 1 ATOM 1564 O OD1 . ASN A 1 207 ? 8.598 3.636 50.579 1.00 34.41 ? 207 ASN A OD1 1 ATOM 1565 N ND2 . ASN A 1 207 ? 8.223 1.540 51.332 1.00 33.19 ? 207 ASN A ND2 1 ATOM 1566 N N . PHE A 1 208 ? 9.358 1.706 45.760 1.00 29.69 ? 208 PHE A N 1 ATOM 1567 C CA . PHE A 1 208 ? 9.919 0.931 44.636 1.00 29.17 ? 208 PHE A CA 1 ATOM 1568 C C . PHE A 1 208 ? 10.788 1.757 43.735 1.00 29.46 ? 208 PHE A C 1 ATOM 1569 O O . PHE A 1 208 ? 11.694 1.204 43.135 1.00 29.19 ? 208 PHE A O 1 ATOM 1570 C CB . PHE A 1 208 ? 8.862 0.175 43.810 1.00 29.06 ? 208 PHE A CB 1 ATOM 1571 C CG . PHE A 1 208 ? 9.445 -0.620 42.625 1.00 28.42 ? 208 PHE A CG 1 ATOM 1572 C CD1 . PHE A 1 208 ? 10.051 -1.880 42.821 1.00 29.39 ? 208 PHE A CD1 1 ATOM 1573 C CD2 . PHE A 1 208 ? 9.364 -0.126 41.320 1.00 27.28 ? 208 PHE A CD2 1 ATOM 1574 C CE1 . PHE A 1 208 ? 10.592 -2.613 41.737 1.00 27.65 ? 208 PHE A CE1 1 ATOM 1575 C CE2 . PHE A 1 208 ? 9.892 -0.845 40.229 1.00 25.92 ? 208 PHE A CE2 1 ATOM 1576 C CZ . PHE A 1 208 ? 10.501 -2.089 40.438 1.00 27.46 ? 208 PHE A CZ 1 ATOM 1577 N N . THR A 1 209 ? 10.543 3.064 43.648 1.00 29.76 ? 209 THR A N 1 ATOM 1578 C CA . THR A 1 209 ? 11.430 3.905 42.851 1.00 31.64 ? 209 THR A CA 1 ATOM 1579 C C . THR A 1 209 ? 12.815 4.093 43.486 1.00 32.27 ? 209 THR A C 1 ATOM 1580 O O . THR A 1 209 ? 13.788 4.443 42.793 1.00 33.07 ? 209 THR A O 1 ATOM 1581 C CB . THR A 1 209 ? 10.879 5.302 42.579 1.00 31.25 ? 209 THR A CB 1 ATOM 1582 O OG1 . THR A 1 209 ? 10.557 5.910 43.816 1.00 35.07 ? 209 THR A OG1 1 ATOM 1583 C CG2 . THR A 1 209 ? 9.647 5.279 41.718 1.00 31.68 ? 209 THR A CG2 1 ATOM 1584 N N . ALA A 1 210 ? 12.900 3.892 44.800 1.00 33.05 ? 210 ALA A N 1 ATOM 1585 C CA . ALA A 1 210 ? 14.161 4.032 45.534 1.00 33.05 ? 210 ALA A CA 1 ATOM 1586 C C . ALA A 1 210 ? 15.072 2.833 45.269 1.00 33.66 ? 210 ALA A C 1 ATOM 1587 O O . ALA A 1 210 ? 16.277 2.885 45.515 1.00 33.40 ? 210 ALA A O 1 ATOM 1588 C CB . ALA A 1 210 ? 13.907 4.205 47.022 1.00 32.83 ? 210 ALA A CB 1 ATOM 1589 N N . THR A 1 211 ? 14.500 1.763 44.725 1.00 33.94 ? 211 THR A N 1 ATOM 1590 C CA . THR A 1 211 ? 15.294 0.590 44.417 1.00 34.36 ? 211 THR A CA 1 ATOM 1591 C C . THR A 1 211 ? 15.963 0.606 43.032 1.00 34.29 ? 211 THR A C 1 ATOM 1592 O O . THR A 1 211 ? 16.805 -0.256 42.746 1.00 34.46 ? 211 THR A O 1 ATOM 1593 C CB . THR A 1 211 ? 14.463 -0.663 44.495 1.00 34.35 ? 211 THR A CB 1 ATOM 1594 O OG1 . THR A 1 211 ? 13.577 -0.675 43.390 1.00 35.70 ? 211 THR A OG1 1 ATOM 1595 C CG2 . THR A 1 211 ? 13.653 -0.730 45.811 1.00 35.92 ? 211 THR A CG2 1 ATOM 1596 N N . PHE A 1 212 ? 15.592 1.544 42.162 1.00 33.68 ? 212 PHE A N 1 ATOM 1597 C CA . PHE A 1 212 ? 16.085 1.474 40.771 1.00 33.31 ? 212 PHE A CA 1 ATOM 1598 C C . PHE A 1 212 ? 16.354 2.786 40.056 1.00 31.98 ? 212 PHE A C 1 ATOM 1599 O O . PHE A 1 212 ? 17.201 2.834 39.173 1.00 31.63 ? 212 PHE A O 1 ATOM 1600 C CB . PHE A 1 212 ? 15.204 0.562 39.892 1.00 33.60 ? 212 PHE A CB 1 ATOM 1601 C CG . PHE A 1 212 ? 14.050 1.274 39.227 1.00 34.33 ? 212 PHE A CG 1 ATOM 1602 C CD1 . PHE A 1 212 ? 12.821 1.376 39.869 1.00 32.26 ? 212 PHE A CD1 1 ATOM 1603 C CD2 . PHE A 1 212 ? 14.186 1.812 37.934 1.00 34.72 ? 212 PHE A CD2 1 ATOM 1604 C CE1 . PHE A 1 212 ? 11.746 2.043 39.252 1.00 32.94 ? 212 PHE A CE1 1 ATOM 1605 C CE2 . PHE A 1 212 ? 13.115 2.474 37.309 1.00 34.51 ? 212 PHE A CE2 1 ATOM 1606 C CZ . PHE A 1 212 ? 11.892 2.589 37.974 1.00 33.84 ? 212 PHE A CZ 1 ATOM 1607 N N . VAL A 1 213 ? 15.625 3.827 40.418 1.00 31.23 ? 213 VAL A N 1 ATOM 1608 C CA . VAL A 1 213 ? 15.871 5.161 39.852 1.00 31.05 ? 213 VAL A CA 1 ATOM 1609 C C . VAL A 1 213 ? 17.238 5.830 40.235 1.00 30.93 ? 213 VAL A C 1 ATOM 1610 O O . VAL A 1 213 ? 17.844 6.466 39.369 1.00 30.79 ? 213 VAL A O 1 ATOM 1611 C CB . VAL A 1 213 ? 14.638 6.107 40.041 1.00 31.19 ? 213 VAL A CB 1 ATOM 1612 C CG1 . VAL A 1 213 ? 14.874 7.495 39.478 1.00 30.94 ? 213 VAL A CG1 1 ATOM 1613 C CG2 . VAL A 1 213 ? 13.413 5.505 39.392 1.00 31.15 ? 213 VAL A CG2 1 ATOM 1614 N N . PRO A 1 214 ? 17.738 5.676 41.499 1.00 30.79 ? 214 PRO A N 1 ATOM 1615 C CA . PRO A 1 214 ? 19.041 6.295 41.867 1.00 30.22 ? 214 PRO A CA 1 ATOM 1616 C C . PRO A 1 214 ? 20.245 5.995 40.951 1.00 29.73 ? 214 PRO A C 1 ATOM 1617 O O . PRO A 1 214 ? 21.008 6.892 40.666 1.00 29.34 ? 214 PRO A O 1 ATOM 1618 C CB . PRO A 1 214 ? 19.304 5.756 43.275 1.00 29.72 ? 214 PRO A CB 1 ATOM 1619 C CG . PRO A 1 214 ? 17.959 5.595 43.845 1.00 31.03 ? 214 PRO A CG 1 ATOM 1620 C CD . PRO A 1 214 ? 17.095 5.074 42.689 1.00 30.98 ? 214 PRO A CD 1 ATOM 1621 N N . SER A 1 215 ? 20.417 4.756 40.510 1.00 29.68 ? 215 SER A N 1 ATOM 1622 C CA . SER A 1 215 ? 21.474 4.395 39.563 1.00 30.36 ? 215 SER A CA 1 ATOM 1623 C C . SER A 1 215 ? 21.367 5.147 38.215 1.00 30.42 ? 215 SER A C 1 ATOM 1624 O O . SER A 1 215 ? 22.366 5.306 37.514 1.00 30.19 ? 215 SER A O 1 ATOM 1625 C CB . SER A 1 215 ? 21.396 2.902 39.210 1.00 30.30 ? 215 SER A CB 1 ATOM 1626 O OG . SER A 1 215 ? 21.064 2.098 40.310 1.00 32.73 ? 215 SER A OG 1 ATOM 1627 N N . ILE A 1 216 ? 20.146 5.535 37.841 1.00 30.22 ? 216 ILE A N 1 ATOM 1628 C CA . ILE A 1 216 ? 19.861 6.149 36.561 1.00 30.18 ? 216 ILE A CA 1 ATOM 1629 C C . ILE A 1 216 ? 20.148 7.621 36.742 1.00 30.39 ? 216 ILE A C 1 ATOM 1630 O O . ILE A 1 216 ? 20.863 8.217 35.923 1.00 30.98 ? 216 ILE A O 1 ATOM 1631 C CB . ILE A 1 216 ? 18.388 5.946 36.132 1.00 30.25 ? 216 ILE A CB 1 ATOM 1632 C CG1 . ILE A 1 216 ? 18.046 4.465 36.009 1.00 30.62 ? 216 ILE A CG1 1 ATOM 1633 C CG2 . ILE A 1 216 ? 18.112 6.613 34.831 1.00 29.52 ? 216 ILE A CG2 1 ATOM 1634 C CD1 . ILE A 1 216 ? 16.496 4.207 36.039 1.00 31.80 ? 216 ILE A CD1 1 ATOM 1635 N N . ARG A 1 217 ? 19.608 8.201 37.820 1.00 29.86 ? 217 ARG A N 1 ATOM 1636 C CA . ARG A 1 217 ? 19.954 9.566 38.250 1.00 29.92 ? 217 ARG A CA 1 ATOM 1637 C C . ARG A 1 217 ? 21.476 9.820 38.248 1.00 29.75 ? 217 ARG A C 1 ATOM 1638 O O . ARG A 1 217 ? 21.943 10.823 37.689 1.00 29.03 ? 217 ARG A O 1 ATOM 1639 C CB . ARG A 1 217 ? 19.375 9.873 39.638 1.00 29.63 ? 217 ARG A CB 1 ATOM 1640 C CG . ARG A 1 217 ? 19.572 11.333 40.042 1.00 31.84 ? 217 ARG A CG 1 ATOM 1641 C CD . ARG A 1 217 ? 19.551 11.619 41.576 1.00 32.51 ? 217 ARG A CD 1 ATOM 1642 N NE . ARG A 1 217 ? 20.109 10.557 42.433 1.00 34.38 ? 217 ARG A NE 1 ATOM 1643 C CZ . ARG A 1 217 ? 21.402 10.392 42.739 1.00 30.66 ? 217 ARG A CZ 1 ATOM 1644 N NH1 . ARG A 1 217 ? 22.334 11.192 42.234 1.00 26.68 ? 217 ARG A NH1 1 ATOM 1645 N NH2 . ARG A 1 217 ? 21.760 9.376 43.521 1.00 27.87 ? 217 ARG A NH2 1 ATOM 1646 N N . GLN A 1 218 ? 22.230 8.913 38.870 1.00 29.80 ? 218 GLN A N 1 ATOM 1647 C CA . GLN A 1 218 ? 23.675 9.058 38.977 1.00 31.09 ? 218 GLN A CA 1 ATOM 1648 C C . GLN A 1 218 ? 24.233 9.181 37.566 1.00 30.94 ? 218 GLN A C 1 ATOM 1649 O O . GLN A 1 218 ? 24.846 10.207 37.220 1.00 30.17 ? 218 GLN A O 1 ATOM 1650 C CB . GLN A 1 218 ? 24.273 7.860 39.686 1.00 31.09 ? 218 GLN A CB 1 ATOM 1651 C CG . GLN A 1 218 ? 25.601 8.120 40.362 1.00 33.68 ? 218 GLN A CG 1 ATOM 1652 C CD . GLN A 1 218 ? 25.818 7.142 41.514 1.00 36.29 ? 218 GLN A CD 1 ATOM 1653 O OE1 . GLN A 1 218 ? 25.710 5.921 41.342 1.00 36.13 ? 218 GLN A OE1 1 ATOM 1654 N NE2 . GLN A 1 218 ? 26.072 7.677 42.699 1.00 36.04 ? 218 GLN A NE2 1 ATOM 1655 N N . ARG A 1 219 ? 23.934 8.161 36.754 1.00 31.13 ? 219 ARG A N 1 ATOM 1656 C CA . ARG A 1 219 ? 24.378 8.099 35.369 1.00 31.67 ? 219 ARG A CA 1 ATOM 1657 C C . ARG A 1 219 ? 24.014 9.338 34.602 1.00 31.99 ? 219 ARG A C 1 ATOM 1658 O O . ARG A 1 219 ? 24.867 9.908 33.952 1.00 32.97 ? 219 ARG A O 1 ATOM 1659 C CB . ARG A 1 219 ? 23.884 6.849 34.634 1.00 31.02 ? 219 ARG A CB 1 ATOM 1660 C CG . ARG A 1 219 ? 24.604 6.660 33.288 1.00 31.03 ? 219 ARG A CG 1 ATOM 1661 C CD . ARG A 1 219 ? 24.122 5.443 32.478 1.00 32.09 ? 219 ARG A CD 1 ATOM 1662 N NE . ARG A 1 219 ? 22.716 5.569 32.082 1.00 31.67 ? 219 ARG A NE 1 ATOM 1663 C CZ . ARG A 1 219 ? 21.724 4.812 32.558 1.00 32.15 ? 219 ARG A CZ 1 ATOM 1664 N NH1 . ARG A 1 219 ? 21.963 3.837 33.456 1.00 31.49 ? 219 ARG A NH1 1 ATOM 1665 N NH2 . ARG A 1 219 ? 20.488 5.023 32.122 1.00 32.14 ? 219 ARG A NH2 1 ATOM 1666 N N . LEU A 1 220 ? 22.769 9.775 34.694 1.00 32.50 ? 220 LEU A N 1 ATOM 1667 C CA . LEU A 1 220 ? 22.365 10.975 33.978 1.00 33.37 ? 220 LEU A CA 1 ATOM 1668 C C . LEU A 1 220 ? 23.079 12.258 34.430 1.00 34.01 ? 220 LEU A C 1 ATOM 1669 O O . LEU A 1 220 ? 23.315 13.146 33.615 1.00 34.14 ? 220 LEU A O 1 ATOM 1670 C CB . LEU A 1 220 ? 20.856 11.174 34.063 1.00 33.45 ? 220 LEU A CB 1 ATOM 1671 C CG . LEU A 1 220 ? 19.890 10.185 33.409 1.00 34.18 ? 220 LEU A CG 1 ATOM 1672 C CD1 . LEU A 1 220 ? 18.425 10.617 33.698 1.00 31.95 ? 220 LEU A CD1 1 ATOM 1673 C CD2 . LEU A 1 220 ? 20.195 10.064 31.898 1.00 32.72 ? 220 LEU A CD2 1 ATOM 1674 N N . GLU A 1 221 ? 23.370 12.384 35.730 1.00 35.20 ? 221 GLU A N 1 ATOM 1675 C CA . GLU A 1 221 ? 24.089 13.567 36.247 1.00 36.00 ? 221 GLU A CA 1 ATOM 1676 C C . GLU A 1 221 ? 25.542 13.473 35.822 1.00 36.30 ? 221 GLU A C 1 ATOM 1677 O O . GLU A 1 221 ? 26.186 14.480 35.573 1.00 36.15 ? 221 GLU A O 1 ATOM 1678 C CB . GLU A 1 221 ? 23.994 13.689 37.778 1.00 35.73 ? 221 GLU A CB 1 ATOM 1679 C CG . GLU A 1 221 ? 22.678 14.234 38.291 1.00 36.40 ? 221 GLU A CG 1 ATOM 1680 C CD . GLU A 1 221 ? 22.528 14.092 39.798 1.00 36.82 ? 221 GLU A CD 1 ATOM 1681 O OE1 . GLU A 1 221 ? 23.090 13.142 40.384 1.00 38.89 ? 221 GLU A OE1 1 ATOM 1682 O OE2 . GLU A 1 221 ? 21.840 14.937 40.404 1.00 37.15 ? 221 GLU A OE2 1 ATOM 1683 N N . ASN A 1 222 ? 26.027 12.242 35.724 1.00 37.09 ? 222 ASN A N 1 ATOM 1684 C CA . ASN A 1 222 ? 27.379 11.979 35.290 1.00 38.34 ? 222 ASN A CA 1 ATOM 1685 C C . ASN A 1 222 ? 27.585 12.423 33.856 1.00 38.29 ? 222 ASN A C 1 ATOM 1686 O O . ASN A 1 222 ? 28.598 13.055 33.541 1.00 38.33 ? 222 ASN A O 1 ATOM 1687 C CB . ASN A 1 222 ? 27.654 10.487 35.371 1.00 38.90 ? 222 ASN A CB 1 ATOM 1688 C CG . ASN A 1 222 ? 28.837 10.158 36.263 1.00 42.84 ? 222 ASN A CG 1 ATOM 1689 O OD1 . ASN A 1 222 ? 29.934 9.841 35.774 1.00 46.68 ? 222 ASN A OD1 1 ATOM 1690 N ND2 . ASN A 1 222 ? 28.620 10.215 37.581 1.00 43.88 ? 222 ASN A ND2 1 ATOM 1691 N N . ASP A 1 223 ? 26.623 12.085 32.997 1.00 37.92 ? 223 ASP A N 1 ATOM 1692 C CA . ASP A 1 223 ? 26.738 12.335 31.567 1.00 38.12 ? 223 ASP A CA 1 ATOM 1693 C C . ASP A 1 223 ? 26.391 13.782 31.219 1.00 37.95 ? 223 ASP A C 1 ATOM 1694 O O . ASP A 1 223 ? 26.874 14.317 30.223 1.00 38.25 ? 223 ASP A O 1 ATOM 1695 C CB . ASP A 1 223 ? 25.819 11.408 30.769 1.00 38.17 ? 223 ASP A CB 1 ATOM 1696 C CG . ASP A 1 223 ? 26.201 9.929 30.864 1.00 39.60 ? 223 ASP A CG 1 ATOM 1697 O OD1 . ASP A 1 223 ? 27.413 9.610 30.895 1.00 40.95 ? 223 ASP A OD1 1 ATOM 1698 O OD2 . ASP A 1 223 ? 25.262 9.073 30.867 1.00 39.88 ? 223 ASP A OD2 1 ATOM 1699 N N . LEU A 1 224 ? 25.526 14.403 32.015 1.00 37.62 ? 224 LEU A N 1 ATOM 1700 C CA . LEU A 1 224 ? 25.135 15.789 31.792 1.00 37.26 ? 224 LEU A CA 1 ATOM 1701 C C . LEU A 1 224 ? 25.691 16.684 32.899 1.00 37.46 ? 224 LEU A C 1 ATOM 1702 O O . LEU A 1 224 ? 24.972 17.057 33.834 1.00 37.56 ? 224 LEU A O 1 ATOM 1703 C CB . LEU A 1 224 ? 23.618 15.897 31.713 1.00 37.38 ? 224 LEU A CB 1 ATOM 1704 C CG . LEU A 1 224 ? 22.904 15.337 30.467 1.00 37.34 ? 224 LEU A CG 1 ATOM 1705 C CD1 . LEU A 1 224 ? 21.545 14.683 30.849 1.00 36.41 ? 224 LEU A CD1 1 ATOM 1706 C CD2 . LEU A 1 224 ? 22.715 16.410 29.393 1.00 35.17 ? 224 LEU A CD2 1 ATOM 1707 N N . SER A 1 225 ? 26.982 17.019 32.780 1.00 37.41 ? 225 SER A N 1 ATOM 1708 C CA . SER A 1 225 ? 27.729 17.816 33.775 1.00 37.31 ? 225 SER A CA 1 ATOM 1709 C C . SER A 1 225 ? 27.138 19.174 34.079 1.00 36.71 ? 225 SER A C 1 ATOM 1710 O O . SER A 1 225 ? 27.039 20.002 33.201 1.00 37.35 ? 225 SER A O 1 ATOM 1711 C CB . SER A 1 225 ? 29.174 18.021 33.298 1.00 37.67 ? 225 SER A CB 1 ATOM 1712 O OG . SER A 1 225 ? 29.945 16.848 33.522 1.00 39.78 ? 225 SER A OG 1 ATOM 1713 N N . GLY A 1 226 ? 26.781 19.420 35.330 1.00 36.40 ? 226 GLY A N 1 ATOM 1714 C CA . GLY A 1 226 ? 26.159 20.693 35.712 1.00 36.34 ? 226 GLY A CA 1 ATOM 1715 C C . GLY A 1 226 ? 24.690 20.560 36.119 1.00 35.78 ? 226 GLY A C 1 ATOM 1716 O O . GLY A 1 226 ? 24.092 21.484 36.690 1.00 36.25 ? 226 GLY A O 1 ATOM 1717 N N . VAL A 1 227 ? 24.128 19.386 35.866 1.00 34.85 ? 227 VAL A N 1 ATOM 1718 C CA . VAL A 1 227 ? 22.709 19.113 36.095 1.00 33.59 ? 227 VAL A CA 1 ATOM 1719 C C . VAL A 1 227 ? 22.542 18.360 37.397 1.00 33.07 ? 227 VAL A C 1 ATOM 1720 O O . VAL A 1 227 ? 23.324 17.461 37.707 1.00 32.28 ? 227 VAL A O 1 ATOM 1721 C CB . VAL A 1 227 ? 22.180 18.240 34.936 1.00 33.52 ? 227 VAL A CB 1 ATOM 1722 C CG1 . VAL A 1 227 ? 21.041 17.322 35.381 1.00 34.08 ? 227 VAL A CG1 1 ATOM 1723 C CG2 . VAL A 1 227 ? 21.787 19.108 33.744 1.00 33.07 ? 227 VAL A CG2 1 ATOM 1724 N N . THR A 1 228 ? 21.516 18.698 38.164 1.00 32.69 ? 228 THR A N 1 ATOM 1725 C CA . THR A 1 228 ? 21.254 17.920 39.364 1.00 32.62 ? 228 THR A CA 1 ATOM 1726 C C . THR A 1 228 ? 19.783 17.518 39.341 1.00 32.15 ? 228 THR A C 1 ATOM 1727 O O . THR A 1 228 ? 18.923 18.343 39.071 1.00 32.58 ? 228 THR A O 1 ATOM 1728 C CB . THR A 1 228 ? 21.749 18.650 40.698 1.00 32.96 ? 228 THR A CB 1 ATOM 1729 O OG1 . THR A 1 228 ? 20.668 19.286 41.385 1.00 33.21 ? 228 THR A OG1 1 ATOM 1730 C CG2 . THR A 1 228 ? 22.825 19.719 40.417 1.00 33.60 ? 228 THR A CG2 1 ATOM 1731 N N . LEU A 1 229 ? 19.496 16.244 39.577 1.00 31.92 ? 229 LEU A N 1 ATOM 1732 C CA . LEU A 1 229 ? 18.162 15.656 39.313 1.00 31.55 ? 229 LEU A CA 1 ATOM 1733 C C . LEU A 1 229 ? 17.558 14.956 40.526 1.00 32.05 ? 229 LEU A C 1 ATOM 1734 O O . LEU A 1 229 ? 18.282 14.287 41.275 1.00 32.25 ? 229 LEU A O 1 ATOM 1735 C CB . LEU A 1 229 ? 18.260 14.637 38.178 1.00 31.03 ? 229 LEU A CB 1 ATOM 1736 C CG . LEU A 1 229 ? 18.450 15.125 36.726 1.00 31.24 ? 229 LEU A CG 1 ATOM 1737 C CD1 . LEU A 1 229 ? 18.856 13.966 35.791 1.00 29.57 ? 229 LEU A CD1 1 ATOM 1738 C CD2 . LEU A 1 229 ? 17.226 15.931 36.167 1.00 28.03 ? 229 LEU A CD2 1 ATOM 1739 N N . THR A 1 230 ? 16.249 15.119 40.735 1.00 31.65 ? 230 THR A N 1 ATOM 1740 C CA . THR A 1 230 ? 15.538 14.287 41.710 1.00 31.73 ? 230 THR A CA 1 ATOM 1741 C C . THR A 1 230 ? 15.029 13.030 41.023 1.00 32.12 ? 230 THR A C 1 ATOM 1742 O O . THR A 1 230 ? 14.757 13.035 39.821 1.00 32.68 ? 230 THR A O 1 ATOM 1743 C CB . THR A 1 230 ? 14.297 14.967 42.343 1.00 31.42 ? 230 THR A CB 1 ATOM 1744 O OG1 . THR A 1 230 ? 13.281 15.124 41.350 1.00 30.44 ? 230 THR A OG1 1 ATOM 1745 C CG2 . THR A 1 230 ? 14.644 16.315 42.971 1.00 30.79 ? 230 THR A CG2 1 ATOM 1746 N N . ASP A 1 231 ? 14.861 11.968 41.794 1.00 32.22 ? 231 ASP A N 1 ATOM 1747 C CA . ASP A 1 231 ? 14.289 10.743 41.270 1.00 32.75 ? 231 ASP A CA 1 ATOM 1748 C C . ASP A 1 231 ? 13.010 10.995 40.432 1.00 32.48 ? 231 ASP A C 1 ATOM 1749 O O . ASP A 1 231 ? 12.794 10.369 39.366 1.00 33.09 ? 231 ASP A O 1 ATOM 1750 C CB . ASP A 1 231 ? 14.022 9.793 42.428 1.00 33.04 ? 231 ASP A CB 1 ATOM 1751 C CG . ASP A 1 231 ? 15.315 9.336 43.110 1.00 34.65 ? 231 ASP A CG 1 ATOM 1752 O OD1 . ASP A 1 231 ? 16.389 9.443 42.471 1.00 36.83 ? 231 ASP A OD1 1 ATOM 1753 O OD2 . ASP A 1 231 ? 15.264 8.847 44.274 1.00 35.91 ? 231 ASP A OD2 1 ATOM 1754 N N . THR A 1 232 ? 12.200 11.945 40.886 1.00 30.94 ? 232 THR A N 1 ATOM 1755 C CA . THR A 1 232 ? 10.909 12.187 40.260 1.00 29.98 ? 232 THR A CA 1 ATOM 1756 C C . THR A 1 232 ? 11.190 12.707 38.882 1.00 29.25 ? 232 THR A C 1 ATOM 1757 O O . THR A 1 232 ? 10.585 12.258 37.904 1.00 30.21 ? 232 THR A O 1 ATOM 1758 C CB . THR A 1 232 ? 9.993 13.115 41.120 1.00 29.74 ? 232 THR A CB 1 ATOM 1759 O OG1 . THR A 1 232 ? 9.663 12.442 42.348 1.00 29.82 ? 232 THR A OG1 1 ATOM 1760 C CG2 . THR A 1 232 ? 8.702 13.402 40.412 1.00 30.34 ? 232 THR A CG2 1 ATOM 1761 N N . GLU A 1 233 ? 12.182 13.585 38.789 1.00 27.84 ? 233 GLU A N 1 ATOM 1762 C CA . GLU A 1 233 ? 12.546 14.150 37.514 1.00 26.55 ? 233 GLU A CA 1 ATOM 1763 C C . GLU A 1 233 ? 13.018 13.074 36.566 1.00 25.64 ? 233 GLU A C 1 ATOM 1764 O O . GLU A 1 233 ? 12.734 13.112 35.396 1.00 25.75 ? 233 GLU A O 1 ATOM 1765 C CB . GLU A 1 233 ? 13.531 15.295 37.701 1.00 26.50 ? 233 GLU A CB 1 ATOM 1766 C CG . GLU A 1 233 ? 12.780 16.533 38.262 1.00 27.88 ? 233 GLU A CG 1 ATOM 1767 C CD . GLU A 1 233 ? 13.661 17.606 38.876 1.00 29.00 ? 233 GLU A CD 1 ATOM 1768 O OE1 . GLU A 1 233 ? 14.878 17.315 39.104 1.00 32.16 ? 233 GLU A OE1 1 ATOM 1769 O OE2 . GLU A 1 233 ? 13.130 18.738 39.110 1.00 27.38 ? 233 GLU A OE2 1 ATOM 1770 N N . VAL A 1 234 ? 13.687 12.067 37.081 1.00 25.19 ? 234 VAL A N 1 ATOM 1771 C CA . VAL A 1 234 ? 14.136 11.013 36.216 1.00 24.83 ? 234 VAL A CA 1 ATOM 1772 C C . VAL A 1 234 ? 12.926 10.285 35.632 1.00 25.34 ? 234 VAL A C 1 ATOM 1773 O O . VAL A 1 234 ? 12.921 9.985 34.453 1.00 24.69 ? 234 VAL A O 1 ATOM 1774 C CB . VAL A 1 234 ? 15.032 10.017 36.931 1.00 25.13 ? 234 VAL A CB 1 ATOM 1775 C CG1 . VAL A 1 234 ? 15.315 8.844 36.009 1.00 24.79 ? 234 VAL A CG1 1 ATOM 1776 C CG2 . VAL A 1 234 ? 16.344 10.686 37.426 1.00 22.95 ? 234 VAL A CG2 1 ATOM 1777 N N . THR A 1 235 ? 11.891 10.019 36.436 1.00 24.99 ? 235 THR A N 1 ATOM 1778 C CA . THR A 1 235 ? 10.727 9.380 35.850 1.00 24.72 ? 235 THR A CA 1 ATOM 1779 C C . THR A 1 235 ? 10.070 10.276 34.784 1.00 24.67 ? 235 THR A C 1 ATOM 1780 O O . THR A 1 235 ? 9.508 9.753 33.813 1.00 24.58 ? 235 THR A O 1 ATOM 1781 C CB . THR A 1 235 ? 9.686 8.863 36.885 1.00 24.83 ? 235 THR A CB 1 ATOM 1782 O OG1 . THR A 1 235 ? 8.922 9.959 37.420 1.00 24.73 ? 235 THR A OG1 1 ATOM 1783 C CG2 . THR A 1 235 ? 10.386 8.074 38.012 1.00 25.22 ? 235 THR A CG2 1 ATOM 1784 N N . TYR A 1 236 ? 10.164 11.602 34.934 1.00 24.34 ? 236 TYR A N 1 ATOM 1785 C CA . TYR A 1 236 ? 9.671 12.510 33.895 1.00 24.51 ? 236 TYR A CA 1 ATOM 1786 C C . TYR A 1 236 ? 10.380 12.302 32.548 1.00 24.55 ? 236 TYR A C 1 ATOM 1787 O O . TYR A 1 236 ? 9.721 12.155 31.541 1.00 25.08 ? 236 TYR A O 1 ATOM 1788 C CB . TYR A 1 236 ? 9.721 13.978 34.315 1.00 24.68 ? 236 TYR A CB 1 ATOM 1789 C CG . TYR A 1 236 ? 8.864 14.350 35.523 1.00 27.81 ? 236 TYR A CG 1 ATOM 1790 C CD1 . TYR A 1 236 ? 7.853 13.499 36.006 1.00 27.89 ? 236 TYR A CD1 1 ATOM 1791 C CD2 . TYR A 1 236 ? 9.057 15.580 36.173 1.00 29.40 ? 236 TYR A CD2 1 ATOM 1792 C CE1 . TYR A 1 236 ? 7.086 13.858 37.121 1.00 30.83 ? 236 TYR A CE1 1 ATOM 1793 C CE2 . TYR A 1 236 ? 8.290 15.959 37.272 1.00 30.41 ? 236 TYR A CE2 1 ATOM 1794 C CZ . TYR A 1 236 ? 7.309 15.096 37.750 1.00 32.59 ? 236 TYR A CZ 1 ATOM 1795 O OH . TYR A 1 236 ? 6.537 15.492 38.840 1.00 34.81 ? 236 TYR A OH 1 ATOM 1796 N N . LEU A 1 237 ? 11.707 12.269 32.511 1.00 24.28 ? 237 LEU A N 1 ATOM 1797 C CA . LEU A 1 237 ? 12.413 11.910 31.264 1.00 24.19 ? 237 LEU A CA 1 ATOM 1798 C C . LEU A 1 237 ? 12.050 10.526 30.707 1.00 25.05 ? 237 LEU A C 1 ATOM 1799 O O . LEU A 1 237 ? 12.112 10.272 29.484 1.00 25.53 ? 237 LEU A O 1 ATOM 1800 C CB . LEU A 1 237 ? 13.918 12.002 31.458 1.00 23.61 ? 237 LEU A CB 1 ATOM 1801 C CG . LEU A 1 237 ? 14.448 13.396 31.813 1.00 23.55 ? 237 LEU A CG 1 ATOM 1802 C CD1 . LEU A 1 237 ? 15.893 13.274 32.189 1.00 23.09 ? 237 LEU A CD1 1 ATOM 1803 C CD2 . LEU A 1 237 ? 14.246 14.475 30.702 1.00 17.74 ? 237 LEU A CD2 1 ATOM 1804 N N . MET A 1 238 ? 11.684 9.611 31.589 1.00 25.17 ? 238 MET A N 1 ATOM 1805 C CA . MET A 1 238 ? 11.187 8.324 31.127 1.00 25.57 ? 238 MET A CA 1 ATOM 1806 C C . MET A 1 238 ? 9.761 8.494 30.549 1.00 26.21 ? 238 MET A C 1 ATOM 1807 O O . MET A 1 238 ? 9.462 7.964 29.464 1.00 26.42 ? 238 MET A O 1 ATOM 1808 C CB . MET A 1 238 ? 11.262 7.285 32.248 1.00 25.36 ? 238 MET A CB 1 ATOM 1809 C CG . MET A 1 238 ? 12.689 6.979 32.678 1.00 25.11 ? 238 MET A CG 1 ATOM 1810 S SD . MET A 1 238 ? 12.884 5.572 33.776 1.00 26.17 ? 238 MET A SD 1 ATOM 1811 C CE . MET A 1 238 ? 12.909 4.194 32.677 1.00 22.11 ? 238 MET A CE 1 ATOM 1812 N N . ASP A 1 239 ? 8.904 9.241 31.260 1.00 25.96 ? 239 ASP A N 1 ATOM 1813 C CA . ASP A 1 239 ? 7.554 9.564 30.781 1.00 26.03 ? 239 ASP A CA 1 ATOM 1814 C C . ASP A 1 239 ? 7.631 10.156 29.357 1.00 26.57 ? 239 ASP A C 1 ATOM 1815 O O . ASP A 1 239 ? 6.865 9.764 28.486 1.00 26.44 ? 239 ASP A O 1 ATOM 1816 C CB . ASP A 1 239 ? 6.844 10.558 31.726 1.00 25.41 ? 239 ASP A CB 1 ATOM 1817 C CG . ASP A 1 239 ? 6.267 9.904 33.020 1.00 24.45 ? 239 ASP A CG 1 ATOM 1818 O OD1 . ASP A 1 239 ? 6.317 8.677 33.252 1.00 22.43 ? 239 ASP A OD1 1 ATOM 1819 O OD2 . ASP A 1 239 ? 5.738 10.660 33.840 1.00 25.35 ? 239 ASP A OD2 1 ATOM 1820 N N . MET A 1 240 ? 8.591 11.054 29.114 1.00 27.26 ? 240 MET A N 1 ATOM 1821 C CA . MET A 1 240 ? 8.771 11.692 27.798 1.00 27.55 ? 240 MET A CA 1 ATOM 1822 C C . MET A 1 240 ? 9.053 10.753 26.627 1.00 28.03 ? 240 MET A C 1 ATOM 1823 O O . MET A 1 240 ? 8.761 11.090 25.484 1.00 28.80 ? 240 MET A O 1 ATOM 1824 C CB . MET A 1 240 ? 9.850 12.759 27.850 1.00 27.56 ? 240 MET A CB 1 ATOM 1825 C CG . MET A 1 240 ? 9.385 14.026 28.524 1.00 28.33 ? 240 MET A CG 1 ATOM 1826 S SD . MET A 1 240 ? 7.941 14.788 27.701 1.00 32.78 ? 240 MET A SD 1 ATOM 1827 C CE . MET A 1 240 ? 8.729 15.264 26.150 1.00 28.62 ? 240 MET A CE 1 ATOM 1828 N N . CYS A 1 241 ? 9.611 9.581 26.886 1.00 28.11 ? 241 CYS A N 1 ATOM 1829 C CA . CYS A 1 241 ? 9.828 8.625 25.813 1.00 28.60 ? 241 CYS A CA 1 ATOM 1830 C C . CYS A 1 241 ? 8.498 8.097 25.207 1.00 28.59 ? 241 CYS A C 1 ATOM 1831 O O . CYS A 1 241 ? 8.395 7.850 24.015 1.00 29.27 ? 241 CYS A O 1 ATOM 1832 C CB . CYS A 1 241 ? 10.720 7.516 26.307 1.00 28.50 ? 241 CYS A CB 1 ATOM 1833 S SG . CYS A 1 241 ? 10.570 6.004 25.374 1.00 32.08 ? 241 CYS A SG 1 ATOM 1834 N N . SER A 1 242 ? 7.463 7.963 26.023 1.00 28.12 ? 242 SER A N 1 ATOM 1835 C CA . SER A 1 242 ? 6.173 7.610 25.498 1.00 26.94 ? 242 SER A CA 1 ATOM 1836 C C . SER A 1 242 ? 5.613 8.802 24.703 1.00 27.16 ? 242 SER A C 1 ATOM 1837 O O . SER A 1 242 ? 5.351 8.687 23.497 1.00 26.56 ? 242 SER A O 1 ATOM 1838 C CB . SER A 1 242 ? 5.237 7.226 26.632 1.00 26.77 ? 242 SER A CB 1 ATOM 1839 O OG . SER A 1 242 ? 4.045 6.692 26.120 1.00 25.12 ? 242 SER A OG 1 ATOM 1840 N N . PHE A 1 243 ? 5.483 9.947 25.375 1.00 26.78 ? 243 PHE A N 1 ATOM 1841 C CA . PHE A 1 243 ? 4.847 11.127 24.809 1.00 27.13 ? 243 PHE A CA 1 ATOM 1842 C C . PHE A 1 243 ? 5.526 11.711 23.580 1.00 27.71 ? 243 PHE A C 1 ATOM 1843 O O . PHE A 1 243 ? 4.858 12.123 22.645 1.00 28.05 ? 243 PHE A O 1 ATOM 1844 C CB . PHE A 1 243 ? 4.729 12.183 25.882 1.00 27.15 ? 243 PHE A CB 1 ATOM 1845 C CG . PHE A 1 243 ? 3.700 11.856 26.913 1.00 27.33 ? 243 PHE A CG 1 ATOM 1846 C CD1 . PHE A 1 243 ? 2.344 11.873 26.587 1.00 26.74 ? 243 PHE A CD1 1 ATOM 1847 C CD2 . PHE A 1 243 ? 4.082 11.514 28.208 1.00 26.47 ? 243 PHE A CD2 1 ATOM 1848 C CE1 . PHE A 1 243 ? 1.384 11.560 27.531 1.00 27.87 ? 243 PHE A CE1 1 ATOM 1849 C CE2 . PHE A 1 243 ? 3.118 11.196 29.175 1.00 27.71 ? 243 PHE A CE2 1 ATOM 1850 C CZ . PHE A 1 243 ? 1.768 11.209 28.834 1.00 27.37 ? 243 PHE A CZ 1 ATOM 1851 N N . ASP A 1 244 ? 6.848 11.749 23.573 1.00 28.37 ? 244 ASP A N 1 ATOM 1852 C CA . ASP A 1 244 ? 7.571 12.264 22.414 1.00 29.00 ? 244 ASP A CA 1 ATOM 1853 C C . ASP A 1 244 ? 7.497 11.285 21.244 1.00 29.87 ? 244 ASP A C 1 ATOM 1854 O O . ASP A 1 244 ? 7.663 11.664 20.096 1.00 30.59 ? 244 ASP A O 1 ATOM 1855 C CB . ASP A 1 244 ? 9.017 12.609 22.773 1.00 28.53 ? 244 ASP A CB 1 ATOM 1856 C CG . ASP A 1 244 ? 9.731 13.385 21.679 1.00 28.20 ? 244 ASP A CG 1 ATOM 1857 O OD1 . ASP A 1 244 ? 9.427 14.570 21.470 1.00 27.67 ? 244 ASP A OD1 1 ATOM 1858 O OD2 . ASP A 1 244 ? 10.612 12.813 21.025 1.00 28.85 ? 244 ASP A OD2 1 ATOM 1859 N N . THR A 1 245 ? 7.242 10.019 21.514 1.00 31.38 ? 245 THR A N 1 ATOM 1860 C CA . THR A 1 245 ? 7.056 9.077 20.418 1.00 32.79 ? 245 THR A CA 1 ATOM 1861 C C . THR A 1 245 ? 5.671 9.243 19.750 1.00 33.80 ? 245 THR A C 1 ATOM 1862 O O . THR A 1 245 ? 5.548 9.638 18.581 1.00 33.96 ? 245 THR A O 1 ATOM 1863 C CB . THR A 1 245 ? 7.309 7.642 20.899 1.00 32.41 ? 245 THR A CB 1 ATOM 1864 O OG1 . THR A 1 245 ? 8.651 7.565 21.376 1.00 34.08 ? 245 THR A OG1 1 ATOM 1865 C CG2 . THR A 1 245 ? 7.146 6.618 19.758 1.00 32.19 ? 245 THR A CG2 1 ATOM 1866 N N . ILE A 1 246 ? 4.641 8.995 20.537 1.00 35.09 ? 246 ILE A N 1 ATOM 1867 C CA . ILE A 1 246 ? 3.316 8.776 20.020 1.00 36.24 ? 246 ILE A CA 1 ATOM 1868 C C . ILE A 1 246 ? 2.460 10.036 19.925 1.00 37.62 ? 246 ILE A C 1 ATOM 1869 O O . ILE A 1 246 ? 1.245 9.954 19.704 1.00 38.26 ? 246 ILE A O 1 ATOM 1870 C CB . ILE A 1 246 ? 2.616 7.626 20.808 1.00 36.13 ? 246 ILE A CB 1 ATOM 1871 C CG1 . ILE A 1 246 ? 2.189 8.058 22.220 1.00 34.52 ? 246 ILE A CG1 1 ATOM 1872 C CG2 . ILE A 1 246 ? 3.501 6.373 20.853 1.00 33.67 ? 246 ILE A CG2 1 ATOM 1873 C CD1 . ILE A 1 246 ? 1.512 6.920 22.985 1.00 32.30 ? 246 ILE A CD1 1 ATOM 1874 N N . SER A 1 247 ? 3.107 11.189 20.067 1.00 39.27 ? 247 SER A N 1 ATOM 1875 C CA . SER A 1 247 ? 2.450 12.496 19.926 1.00 41.17 ? 247 SER A CA 1 ATOM 1876 C C . SER A 1 247 ? 2.695 13.140 18.577 1.00 41.98 ? 247 SER A C 1 ATOM 1877 O O . SER A 1 247 ? 2.013 14.072 18.216 1.00 42.77 ? 247 SER A O 1 ATOM 1878 C CB . SER A 1 247 ? 2.921 13.482 20.995 1.00 41.05 ? 247 SER A CB 1 ATOM 1879 O OG . SER A 1 247 ? 2.434 13.124 22.280 1.00 42.26 ? 247 SER A OG 1 ATOM 1880 N N . THR A 1 248 ? 3.673 12.666 17.830 1.00 43.51 ? 248 THR A N 1 ATOM 1881 C CA . THR A 1 248 ? 3.981 13.307 16.553 1.00 44.96 ? 248 THR A CA 1 ATOM 1882 C C . THR A 1 248 ? 3.670 12.483 15.315 1.00 44.98 ? 248 THR A C 1 ATOM 1883 O O . THR A 1 248 ? 3.159 11.355 15.390 1.00 44.73 ? 248 THR A O 1 ATOM 1884 C CB . THR A 1 248 ? 5.473 13.766 16.457 1.00 45.74 ? 248 THR A CB 1 ATOM 1885 O OG1 . THR A 1 248 ? 5.876 13.830 15.070 1.00 46.94 ? 248 THR A OG1 1 ATOM 1886 C CG2 . THR A 1 248 ? 6.400 12.801 17.221 1.00 45.95 ? 248 THR A CG2 1 ATOM 1887 N N . SER A 1 249 ? 3.998 13.104 14.178 1.00 45.32 ? 249 SER A N 1 ATOM 1888 C CA . SER A 1 249 ? 4.087 12.476 12.857 1.00 45.21 ? 249 SER A CA 1 ATOM 1889 C C . SER A 1 249 ? 4.761 11.116 12.923 1.00 44.48 ? 249 SER A C 1 ATOM 1890 O O . SER A 1 249 ? 4.268 10.130 12.348 1.00 44.68 ? 249 SER A O 1 ATOM 1891 C CB . SER A 1 249 ? 4.908 13.391 11.924 1.00 45.93 ? 249 SER A CB 1 ATOM 1892 O OG . SER A 1 249 ? 5.166 12.774 10.653 1.00 47.17 ? 249 SER A OG 1 ATOM 1893 N N . THR A 1 250 ? 5.874 11.066 13.648 1.00 43.45 ? 250 THR A N 1 ATOM 1894 C CA . THR A 1 250 ? 6.787 9.939 13.553 1.00 42.65 ? 250 THR A CA 1 ATOM 1895 C C . THR A 1 250 ? 6.357 8.709 14.326 1.00 41.94 ? 250 THR A C 1 ATOM 1896 O O . THR A 1 250 ? 7.133 7.744 14.451 1.00 41.32 ? 250 THR A O 1 ATOM 1897 C CB . THR A 1 250 ? 8.255 10.338 13.883 1.00 43.06 ? 250 THR A CB 1 ATOM 1898 O OG1 . THR A 1 250 ? 8.289 11.436 14.815 1.00 42.59 ? 250 THR A OG1 1 ATOM 1899 C CG2 . THR A 1 250 ? 8.934 10.763 12.608 1.00 43.95 ? 250 THR A CG2 1 ATOM 1900 N N . VAL A 1 251 ? 5.114 8.726 14.802 1.00 41.30 ? 251 VAL A N 1 ATOM 1901 C CA . VAL A 1 251 ? 4.619 7.652 15.635 1.00 41.45 ? 251 VAL A CA 1 ATOM 1902 C C . VAL A 1 251 ? 5.019 6.282 15.118 1.00 41.57 ? 251 VAL A C 1 ATOM 1903 O O . VAL A 1 251 ? 5.462 5.437 15.904 1.00 40.90 ? 251 VAL A O 1 ATOM 1904 C CB . VAL A 1 251 ? 3.108 7.790 15.934 1.00 41.61 ? 251 VAL A CB 1 ATOM 1905 C CG1 . VAL A 1 251 ? 2.264 7.787 14.705 1.00 41.82 ? 251 VAL A CG1 1 ATOM 1906 C CG2 . VAL A 1 251 ? 2.665 6.783 16.952 1.00 41.82 ? 251 VAL A CG2 1 ATOM 1907 N N . ASP A 1 252 ? 4.936 6.096 13.796 1.00 42.17 ? 252 ASP A N 1 ATOM 1908 C CA . ASP A 1 252 ? 5.210 4.794 13.153 1.00 42.47 ? 252 ASP A CA 1 ATOM 1909 C C . ASP A 1 252 ? 6.675 4.621 12.689 1.00 42.00 ? 252 ASP A C 1 ATOM 1910 O O . ASP A 1 252 ? 7.141 3.511 12.491 1.00 41.79 ? 252 ASP A O 1 ATOM 1911 C CB . ASP A 1 252 ? 4.213 4.543 12.007 1.00 42.38 ? 252 ASP A CB 1 ATOM 1912 C CG . ASP A 1 252 ? 2.837 4.080 12.506 1.00 44.79 ? 252 ASP A CG 1 ATOM 1913 O OD1 . ASP A 1 252 ? 2.564 2.877 12.418 1.00 47.19 ? 252 ASP A OD1 1 ATOM 1914 O OD2 . ASP A 1 252 ? 2.021 4.889 12.992 1.00 46.77 ? 252 ASP A OD2 1 ATOM 1915 N N . THR A 1 253 ? 7.403 5.720 12.542 1.00 42.49 ? 253 THR A N 1 ATOM 1916 C CA . THR A 1 253 ? 8.720 5.674 11.878 1.00 43.06 ? 253 THR A CA 1 ATOM 1917 C C . THR A 1 253 ? 9.928 5.741 12.821 1.00 43.28 ? 253 THR A C 1 ATOM 1918 O O . THR A 1 253 ? 10.912 5.032 12.598 1.00 43.55 ? 253 THR A O 1 ATOM 1919 C CB . THR A 1 253 ? 8.861 6.745 10.759 1.00 43.12 ? 253 THR A CB 1 ATOM 1920 O OG1 . THR A 1 253 ? 8.229 7.957 11.170 1.00 43.68 ? 253 THR A OG1 1 ATOM 1921 C CG2 . THR A 1 253 ? 8.210 6.286 9.465 1.00 43.53 ? 253 THR A CG2 1 ATOM 1922 N N . LYS A 1 254 ? 9.859 6.589 13.857 1.00 43.22 ? 254 LYS A N 1 ATOM 1923 C CA . LYS A 1 254 ? 10.968 6.745 14.827 1.00 43.22 ? 254 LYS A CA 1 ATOM 1924 C C . LYS A 1 254 ? 10.522 6.602 16.275 1.00 42.47 ? 254 LYS A C 1 ATOM 1925 O O . LYS A 1 254 ? 9.518 7.201 16.693 1.00 42.31 ? 254 LYS A O 1 ATOM 1926 C CB . LYS A 1 254 ? 11.684 8.109 14.696 1.00 43.27 ? 254 LYS A CB 1 ATOM 1927 C CG . LYS A 1 254 ? 12.409 8.382 13.361 1.00 46.87 ? 254 LYS A CG 1 ATOM 1928 C CD . LYS A 1 254 ? 12.915 9.862 13.239 1.00 49.87 ? 254 LYS A CD 1 ATOM 1929 C CE . LYS A 1 254 ? 12.573 10.493 11.858 1.00 50.10 ? 254 LYS A CE 1 ATOM 1930 N NZ . LYS A 1 254 ? 12.806 9.531 10.742 1.00 51.49 ? 254 LYS A NZ 1 ATOM 1931 N N . LEU A 1 255 ? 11.292 5.827 17.036 1.00 41.80 ? 255 LEU A N 1 ATOM 1932 C CA . LEU A 1 255 ? 11.179 5.822 18.498 1.00 41.28 ? 255 LEU A CA 1 ATOM 1933 C C . LEU A 1 255 ? 11.791 7.126 19.057 1.00 40.78 ? 255 LEU A C 1 ATOM 1934 O O . LEU A 1 255 ? 12.832 7.590 18.555 1.00 41.10 ? 255 LEU A O 1 ATOM 1935 C CB . LEU A 1 255 ? 11.864 4.574 19.075 1.00 41.30 ? 255 LEU A CB 1 ATOM 1936 C CG . LEU A 1 255 ? 11.691 4.193 20.552 1.00 40.44 ? 255 LEU A CG 1 ATOM 1937 C CD1 . LEU A 1 255 ? 10.230 4.099 20.934 1.00 39.19 ? 255 LEU A CD1 1 ATOM 1938 C CD2 . LEU A 1 255 ? 12.386 2.877 20.824 1.00 38.48 ? 255 LEU A CD2 1 ATOM 1939 N N . SER A 1 256 ? 11.154 7.738 20.055 1.00 39.55 ? 256 SER A N 1 ATOM 1940 C CA . SER A 1 256 ? 11.682 9.006 20.601 1.00 39.01 ? 256 SER A CA 1 ATOM 1941 C C . SER A 1 256 ? 13.163 8.936 21.012 1.00 38.39 ? 256 SER A C 1 ATOM 1942 O O . SER A 1 256 ? 13.634 7.892 21.470 1.00 38.23 ? 256 SER A O 1 ATOM 1943 C CB . SER A 1 256 ? 10.862 9.481 21.791 1.00 38.94 ? 256 SER A CB 1 ATOM 1944 O OG . SER A 1 256 ? 11.393 10.680 22.301 1.00 38.13 ? 256 SER A OG 1 ATOM 1945 N N . PRO A 1 257 ? 13.904 10.042 20.849 1.00 38.00 ? 257 PRO A N 1 ATOM 1946 C CA . PRO A 1 257 ? 15.315 10.041 21.291 1.00 37.44 ? 257 PRO A CA 1 ATOM 1947 C C . PRO A 1 257 ? 15.467 9.800 22.823 1.00 36.76 ? 257 PRO A C 1 ATOM 1948 O O . PRO A 1 257 ? 16.472 9.197 23.265 1.00 36.24 ? 257 PRO A O 1 ATOM 1949 C CB . PRO A 1 257 ? 15.821 11.444 20.912 1.00 37.66 ? 257 PRO A CB 1 ATOM 1950 C CG . PRO A 1 257 ? 14.800 12.027 19.961 1.00 38.18 ? 257 PRO A CG 1 ATOM 1951 C CD . PRO A 1 257 ? 13.489 11.335 20.264 1.00 38.22 ? 257 PRO A CD 1 ATOM 1952 N N . PHE A 1 258 ? 14.458 10.256 23.583 1.00 35.12 ? 258 PHE A N 1 ATOM 1953 C CA . PHE A 1 258 ? 14.340 10.055 25.023 1.00 33.85 ? 258 PHE A CA 1 ATOM 1954 C C . PHE A 1 258 ? 14.471 8.602 25.450 1.00 32.94 ? 258 PHE A C 1 ATOM 1955 O O . PHE A 1 258 ? 15.011 8.303 26.507 1.00 32.42 ? 258 PHE A O 1 ATOM 1956 C CB . PHE A 1 258 ? 12.995 10.599 25.524 1.00 33.61 ? 258 PHE A CB 1 ATOM 1957 C CG . PHE A 1 258 ? 12.966 12.092 25.705 1.00 33.75 ? 258 PHE A CG 1 ATOM 1958 C CD1 . PHE A 1 258 ? 13.746 12.710 26.678 1.00 34.09 ? 258 PHE A CD1 1 ATOM 1959 C CD2 . PHE A 1 258 ? 12.140 12.887 24.918 1.00 34.52 ? 258 PHE A CD2 1 ATOM 1960 C CE1 . PHE A 1 258 ? 13.703 14.105 26.860 1.00 33.28 ? 258 PHE A CE1 1 ATOM 1961 C CE2 . PHE A 1 258 ? 12.097 14.289 25.077 1.00 34.09 ? 258 PHE A CE2 1 ATOM 1962 C CZ . PHE A 1 258 ? 12.877 14.897 26.048 1.00 33.90 ? 258 PHE A CZ 1 ATOM 1963 N N . CYS A 1 259 ? 13.962 7.703 24.624 1.00 32.13 ? 259 CYS A N 1 ATOM 1964 C CA . CYS A 1 259 ? 13.942 6.284 24.945 1.00 31.85 ? 259 CYS A CA 1 ATOM 1965 C C . CYS A 1 259 ? 15.335 5.675 25.045 1.00 32.22 ? 259 CYS A C 1 ATOM 1966 O O . CYS A 1 259 ? 15.540 4.735 25.836 1.00 32.26 ? 259 CYS A O 1 ATOM 1967 C CB . CYS A 1 259 ? 13.113 5.518 23.923 1.00 31.40 ? 259 CYS A CB 1 ATOM 1968 S SG . CYS A 1 259 ? 11.551 6.280 23.615 1.00 30.66 ? 259 CYS A SG 1 ATOM 1969 N N . ASP A 1 260 ? 16.278 6.216 24.269 1.00 31.92 ? 260 ASP A N 1 ATOM 1970 C CA . ASP A 1 260 ? 17.621 5.647 24.197 1.00 32.75 ? 260 ASP A CA 1 ATOM 1971 C C . ASP A 1 260 ? 18.486 6.008 25.429 1.00 31.86 ? 260 ASP A C 1 ATOM 1972 O O . ASP A 1 260 ? 19.507 5.375 25.681 1.00 31.43 ? 260 ASP A O 1 ATOM 1973 C CB . ASP A 1 260 ? 18.312 5.998 22.868 1.00 33.25 ? 260 ASP A CB 1 ATOM 1974 C CG . ASP A 1 260 ? 19.546 5.098 22.567 1.00 37.74 ? 260 ASP A CG 1 ATOM 1975 O OD1 . ASP A 1 260 ? 19.650 3.927 23.078 1.00 40.38 ? 260 ASP A OD1 1 ATOM 1976 O OD2 . ASP A 1 260 ? 20.430 5.583 21.808 1.00 40.18 ? 260 ASP A OD2 1 ATOM 1977 N N . LEU A 1 261 ? 18.027 6.986 26.219 1.00 31.00 ? 261 LEU A N 1 ATOM 1978 C CA . LEU A 1 261 ? 18.711 7.383 27.468 1.00 29.47 ? 261 LEU A CA 1 ATOM 1979 C C . LEU A 1 261 ? 18.526 6.365 28.590 1.00 28.76 ? 261 LEU A C 1 ATOM 1980 O O . LEU A 1 261 ? 19.152 6.464 29.635 1.00 29.13 ? 261 LEU A O 1 ATOM 1981 C CB . LEU A 1 261 ? 18.231 8.758 27.939 1.00 28.65 ? 261 LEU A CB 1 ATOM 1982 C CG . LEU A 1 261 ? 18.214 9.872 26.901 1.00 27.84 ? 261 LEU A CG 1 ATOM 1983 C CD1 . LEU A 1 261 ? 17.537 11.054 27.534 1.00 25.77 ? 261 LEU A CD1 1 ATOM 1984 C CD2 . LEU A 1 261 ? 19.637 10.240 26.379 1.00 25.91 ? 261 LEU A CD2 1 ATOM 1985 N N . PHE A 1 262 ? 17.679 5.381 28.368 1.00 28.06 ? 262 PHE A N 1 ATOM 1986 C CA . PHE A 1 262 ? 17.464 4.343 29.370 1.00 27.57 ? 262 PHE A CA 1 ATOM 1987 C C . PHE A 1 262 ? 17.654 2.975 28.736 1.00 27.85 ? 262 PHE A C 1 ATOM 1988 O O . PHE A 1 262 ? 17.493 2.823 27.528 1.00 28.47 ? 262 PHE A O 1 ATOM 1989 C CB . PHE A 1 262 ? 16.064 4.520 29.952 1.00 26.55 ? 262 PHE A CB 1 ATOM 1990 C CG . PHE A 1 262 ? 15.789 5.929 30.384 1.00 25.13 ? 262 PHE A CG 1 ATOM 1991 C CD1 . PHE A 1 262 ? 16.285 6.411 31.596 1.00 25.23 ? 262 PHE A CD1 1 ATOM 1992 C CD2 . PHE A 1 262 ? 15.056 6.776 29.595 1.00 21.04 ? 262 PHE A CD2 1 ATOM 1993 C CE1 . PHE A 1 262 ? 16.040 7.740 32.015 1.00 23.54 ? 262 PHE A CE1 1 ATOM 1994 C CE2 . PHE A 1 262 ? 14.799 8.087 30.011 1.00 24.49 ? 262 PHE A CE2 1 ATOM 1995 C CZ . PHE A 1 262 ? 15.306 8.574 31.225 1.00 23.48 ? 262 PHE A CZ 1 ATOM 1996 N N . THR A 1 263 ? 18.034 1.986 29.532 1.00 28.36 ? 263 THR A N 1 ATOM 1997 C CA . THR A 1 263 ? 18.294 0.649 29.015 1.00 28.06 ? 263 THR A CA 1 ATOM 1998 C C . THR A 1 263 ? 17.023 -0.200 29.074 1.00 29.32 ? 263 THR A C 1 ATOM 1999 O O . THR A 1 263 ? 16.045 0.150 29.797 1.00 28.22 ? 263 THR A O 1 ATOM 2000 C CB . THR A 1 263 ? 19.330 -0.061 29.848 1.00 28.12 ? 263 THR A CB 1 ATOM 2001 O OG1 . THR A 1 263 ? 18.785 -0.352 31.142 1.00 25.74 ? 263 THR A OG1 1 ATOM 2002 C CG2 . THR A 1 263 ? 20.590 0.793 29.982 1.00 28.88 ? 263 THR A CG2 1 ATOM 2003 N N . HIS A 1 264 ? 17.055 -1.324 28.341 1.00 29.89 ? 264 HIS A N 1 ATOM 2004 C CA . HIS A 1 264 ? 15.938 -2.257 28.323 1.00 31.20 ? 264 HIS A CA 1 ATOM 2005 C C . HIS A 1 264 ? 15.520 -2.582 29.749 1.00 31.58 ? 264 HIS A C 1 ATOM 2006 O O . HIS A 1 264 ? 14.351 -2.393 30.104 1.00 32.29 ? 264 HIS A O 1 ATOM 2007 C CB . HIS A 1 264 ? 16.277 -3.531 27.535 1.00 31.57 ? 264 HIS A CB 1 ATOM 2008 C CG . HIS A 1 264 ? 15.142 -4.518 27.435 1.00 33.23 ? 264 HIS A CG 1 ATOM 2009 N ND1 . HIS A 1 264 ? 13.962 -4.245 26.771 1.00 34.14 ? 264 HIS A ND1 1 ATOM 2010 C CD2 . HIS A 1 264 ? 15.024 -5.791 27.893 1.00 33.93 ? 264 HIS A CD2 1 ATOM 2011 C CE1 . HIS A 1 264 ? 13.160 -5.294 26.850 1.00 32.98 ? 264 HIS A CE1 1 ATOM 2012 N NE2 . HIS A 1 264 ? 13.782 -6.247 27.518 1.00 33.11 ? 264 HIS A NE2 1 ATOM 2013 N N . ASP A 1 265 ? 16.486 -3.011 30.565 1.00 31.45 ? 265 ASP A N 1 ATOM 2014 C CA . ASP A 1 265 ? 16.231 -3.460 31.932 1.00 31.59 ? 265 ASP A CA 1 ATOM 2015 C C . ASP A 1 265 ? 15.617 -2.335 32.770 1.00 30.45 ? 265 ASP A C 1 ATOM 2016 O O . ASP A 1 265 ? 14.694 -2.555 33.580 1.00 29.76 ? 265 ASP A O 1 ATOM 2017 C CB . ASP A 1 265 ? 17.518 -4.042 32.562 1.00 32.54 ? 265 ASP A CB 1 ATOM 2018 C CG . ASP A 1 265 ? 17.441 -4.110 34.077 1.00 36.20 ? 265 ASP A CG 1 ATOM 2019 O OD1 . ASP A 1 265 ? 18.015 -3.206 34.763 1.00 39.32 ? 265 ASP A OD1 1 ATOM 2020 O OD2 . ASP A 1 265 ? 16.779 -5.054 34.575 1.00 39.40 ? 265 ASP A OD2 1 ATOM 2021 N N . GLU A 1 266 ? 16.121 -1.129 32.540 1.00 29.27 ? 266 GLU A N 1 ATOM 2022 C CA . GLU A 1 266 ? 15.521 0.075 33.082 1.00 28.08 ? 266 GLU A CA 1 ATOM 2023 C C . GLU A 1 266 ? 14.095 0.288 32.609 1.00 27.47 ? 266 GLU A C 1 ATOM 2024 O O . GLU A 1 266 ? 13.262 0.682 33.426 1.00 27.88 ? 266 GLU A O 1 ATOM 2025 C CB . GLU A 1 266 ? 16.372 1.282 32.788 1.00 28.15 ? 266 GLU A CB 1 ATOM 2026 C CG . GLU A 1 266 ? 17.500 1.415 33.787 1.00 29.43 ? 266 GLU A CG 1 ATOM 2027 C CD . GLU A 1 266 ? 18.656 2.260 33.272 1.00 31.69 ? 266 GLU A CD 1 ATOM 2028 O OE1 . GLU A 1 266 ? 18.435 3.222 32.482 1.00 29.68 ? 266 GLU A OE1 1 ATOM 2029 O OE2 . GLU A 1 266 ? 19.800 1.956 33.679 1.00 34.27 ? 266 GLU A OE2 1 ATOM 2030 N N . TRP A 1 267 ? 13.797 -0.011 31.336 1.00 25.83 ? 267 TRP A N 1 ATOM 2031 C CA . TRP A 1 267 ? 12.406 -0.058 30.882 1.00 24.44 ? 267 TRP A CA 1 ATOM 2032 C C . TRP A 1 267 ? 11.567 -1.114 31.632 1.00 24.80 ? 267 TRP A C 1 ATOM 2033 O O . TRP A 1 267 ? 10.423 -0.850 32.016 1.00 24.44 ? 267 TRP A O 1 ATOM 2034 C CB . TRP A 1 267 ? 12.287 -0.174 29.357 1.00 23.58 ? 267 TRP A CB 1 ATOM 2035 C CG . TRP A 1 267 ? 12.639 1.135 28.720 1.00 21.29 ? 267 TRP A CG 1 ATOM 2036 C CD1 . TRP A 1 267 ? 13.709 1.406 27.875 1.00 18.84 ? 267 TRP A CD1 1 ATOM 2037 C CD2 . TRP A 1 267 ? 11.977 2.379 28.928 1.00 17.47 ? 267 TRP A CD2 1 ATOM 2038 N NE1 . TRP A 1 267 ? 13.715 2.738 27.537 1.00 17.22 ? 267 TRP A NE1 1 ATOM 2039 C CE2 . TRP A 1 267 ? 12.672 3.360 28.173 1.00 18.04 ? 267 TRP A CE2 1 ATOM 2040 C CE3 . TRP A 1 267 ? 10.851 2.768 29.672 1.00 18.95 ? 267 TRP A CE3 1 ATOM 2041 C CZ2 . TRP A 1 267 ? 12.280 4.695 28.152 1.00 17.47 ? 267 TRP A CZ2 1 ATOM 2042 C CZ3 . TRP A 1 267 ? 10.471 4.103 29.652 1.00 18.33 ? 267 TRP A CZ3 1 ATOM 2043 C CH2 . TRP A 1 267 ? 11.187 5.048 28.906 1.00 18.37 ? 267 TRP A CH2 1 ATOM 2044 N N . ILE A 1 268 ? 12.155 -2.277 31.893 1.00 24.54 ? 268 ILE A N 1 ATOM 2045 C CA . ILE A 1 268 ? 11.459 -3.324 32.631 1.00 25.02 ? 268 ILE A CA 1 ATOM 2046 C C . ILE A 1 268 ? 10.954 -2.876 34.002 1.00 25.17 ? 268 ILE A C 1 ATOM 2047 O O . ILE A 1 268 ? 9.797 -3.174 34.384 1.00 25.23 ? 268 ILE A O 1 ATOM 2048 C CB . ILE A 1 268 ? 12.303 -4.590 32.760 1.00 25.18 ? 268 ILE A CB 1 ATOM 2049 C CG1 . ILE A 1 268 ? 12.265 -5.363 31.450 1.00 25.53 ? 268 ILE A CG1 1 ATOM 2050 C CG2 . ILE A 1 268 ? 11.762 -5.487 33.861 1.00 25.44 ? 268 ILE A CG2 1 ATOM 2051 C CD1 . ILE A 1 268 ? 13.128 -6.606 31.454 1.00 27.59 ? 268 ILE A CD1 1 ATOM 2052 N N . ASN A 1 269 ? 11.809 -2.157 34.722 1.00 23.91 ? 269 ASN A N 1 ATOM 2053 C CA . ASN A 1 269 ? 11.430 -1.608 35.992 1.00 23.09 ? 269 ASN A CA 1 ATOM 2054 C C . ASN A 1 269 ? 10.344 -0.569 35.806 1.00 22.88 ? 269 ASN A C 1 ATOM 2055 O O . ASN A 1 269 ? 9.332 -0.587 36.521 1.00 23.83 ? 269 ASN A O 1 ATOM 2056 C CB . ASN A 1 269 ? 12.640 -1.011 36.716 1.00 23.09 ? 269 ASN A CB 1 ATOM 2057 C CG . ASN A 1 269 ? 13.611 -2.068 37.211 1.00 25.03 ? 269 ASN A CG 1 ATOM 2058 O OD1 . ASN A 1 269 ? 13.283 -2.918 38.039 1.00 27.69 ? 269 ASN A OD1 1 ATOM 2059 N ND2 . ASN A 1 269 ? 14.818 -2.010 36.710 1.00 26.89 ? 269 ASN A ND2 1 ATOM 2060 N N . TYR A 1 270 ? 10.541 0.344 34.854 1.00 22.43 ? 270 TYR A N 1 ATOM 2061 C CA . TYR A 1 270 ? 9.529 1.359 34.564 1.00 21.32 ? 270 TYR A CA 1 ATOM 2062 C C . TYR A 1 270 ? 8.138 0.728 34.407 1.00 20.88 ? 270 TYR A C 1 ATOM 2063 O O . TYR A 1 270 ? 7.178 1.114 35.115 1.00 19.42 ? 270 TYR A O 1 ATOM 2064 C CB . TYR A 1 270 ? 9.892 2.131 33.318 1.00 21.36 ? 270 TYR A CB 1 ATOM 2065 C CG . TYR A 1 270 ? 8.969 3.303 33.029 1.00 22.44 ? 270 TYR A CG 1 ATOM 2066 C CD1 . TYR A 1 270 ? 9.119 4.528 33.683 1.00 21.02 ? 270 TYR A CD1 1 ATOM 2067 C CD2 . TYR A 1 270 ? 7.944 3.179 32.098 1.00 22.26 ? 270 TYR A CD2 1 ATOM 2068 C CE1 . TYR A 1 270 ? 8.252 5.598 33.413 1.00 20.47 ? 270 TYR A CE1 1 ATOM 2069 C CE2 . TYR A 1 270 ? 7.075 4.220 31.839 1.00 22.11 ? 270 TYR A CE2 1 ATOM 2070 C CZ . TYR A 1 270 ? 7.236 5.432 32.478 1.00 23.30 ? 270 TYR A CZ 1 ATOM 2071 O OH . TYR A 1 270 ? 6.359 6.469 32.149 1.00 21.84 ? 270 TYR A OH 1 ATOM 2072 N N . ASP A 1 271 ? 8.046 -0.279 33.528 1.00 20.20 ? 271 ASP A N 1 ATOM 2073 C CA . ASP A 1 271 ? 6.779 -0.975 33.316 1.00 19.88 ? 271 ASP A CA 1 ATOM 2074 C C . ASP A 1 271 ? 6.203 -1.491 34.617 1.00 19.94 ? 271 ASP A C 1 ATOM 2075 O O . ASP A 1 271 ? 5.028 -1.240 34.941 1.00 20.72 ? 271 ASP A O 1 ATOM 2076 C CB . ASP A 1 271 ? 6.942 -2.102 32.306 1.00 20.46 ? 271 ASP A CB 1 ATOM 2077 C CG . ASP A 1 271 ? 5.634 -2.781 31.977 1.00 20.12 ? 271 ASP A CG 1 ATOM 2078 O OD1 . ASP A 1 271 ? 4.790 -2.158 31.292 1.00 15.30 ? 271 ASP A OD1 1 ATOM 2079 O OD2 . ASP A 1 271 ? 5.488 -3.952 32.398 1.00 20.16 ? 271 ASP A OD2 1 ATOM 2080 N N . TYR A 1 272 ? 7.055 -2.147 35.402 1.00 19.28 ? 272 TYR A N 1 ATOM 2081 C CA . TYR A 1 272 ? 6.621 -2.777 36.619 1.00 18.51 ? 272 TYR A CA 1 ATOM 2082 C C . TYR A 1 272 ? 6.165 -1.762 37.631 1.00 18.33 ? 272 TYR A C 1 ATOM 2083 O O . TYR A 1 272 ? 5.161 -1.990 38.334 1.00 17.85 ? 272 TYR A O 1 ATOM 2084 C CB . TYR A 1 272 ? 7.737 -3.647 37.206 1.00 19.15 ? 272 TYR A CB 1 ATOM 2085 C CG . TYR A 1 272 ? 7.244 -4.487 38.360 1.00 19.62 ? 272 TYR A CG 1 ATOM 2086 C CD1 . TYR A 1 272 ? 6.378 -5.579 38.146 1.00 20.49 ? 272 TYR A CD1 1 ATOM 2087 C CD2 . TYR A 1 272 ? 7.609 -4.183 39.655 1.00 19.20 ? 272 TYR A CD2 1 ATOM 2088 C CE1 . TYR A 1 272 ? 5.899 -6.334 39.221 1.00 21.99 ? 272 TYR A CE1 1 ATOM 2089 C CE2 . TYR A 1 272 ? 7.155 -4.947 40.724 1.00 21.11 ? 272 TYR A CE2 1 ATOM 2090 C CZ . TYR A 1 272 ? 6.305 -6.008 40.509 1.00 21.34 ? 272 TYR A CZ 1 ATOM 2091 O OH . TYR A 1 272 ? 5.845 -6.726 41.598 1.00 23.35 ? 272 TYR A OH 1 ATOM 2092 N N . LEU A 1 273 ? 6.901 -0.649 37.711 1.00 18.01 ? 273 LEU A N 1 ATOM 2093 C CA . LEU A 1 273 ? 6.452 0.482 38.525 1.00 18.23 ? 273 LEU A CA 1 ATOM 2094 C C . LEU A 1 273 ? 5.006 0.837 38.194 1.00 18.23 ? 273 LEU A C 1 ATOM 2095 O O . LEU A 1 273 ? 4.211 1.070 39.105 1.00 19.33 ? 273 LEU A O 1 ATOM 2096 C CB . LEU A 1 273 ? 7.292 1.732 38.311 1.00 17.43 ? 273 LEU A CB 1 ATOM 2097 C CG . LEU A 1 273 ? 6.633 2.983 38.951 1.00 19.20 ? 273 LEU A CG 1 ATOM 2098 C CD1 . LEU A 1 273 ? 6.875 3.098 40.481 1.00 20.40 ? 273 LEU A CD1 1 ATOM 2099 C CD2 . LEU A 1 273 ? 7.113 4.234 38.314 1.00 22.29 ? 273 LEU A CD2 1 ATOM 2100 N N . GLN A 1 274 ? 4.686 0.923 36.894 1.00 18.39 ? 274 GLN A N 1 ATOM 2101 C CA . GLN A 1 274 ? 3.352 1.344 36.439 1.00 17.51 ? 274 GLN A CA 1 ATOM 2102 C C . GLN A 1 274 ? 2.328 0.269 36.855 1.00 17.09 ? 274 GLN A C 1 ATOM 2103 O O . GLN A 1 274 ? 1.254 0.596 37.345 1.00 18.08 ? 274 GLN A O 1 ATOM 2104 C CB . GLN A 1 274 ? 3.295 1.560 34.917 1.00 17.83 ? 274 GLN A CB 1 ATOM 2105 C CG . GLN A 1 274 ? 4.223 2.573 34.255 1.00 16.39 ? 274 GLN A CG 1 ATOM 2106 C CD . GLN A 1 274 ? 4.415 3.882 35.016 1.00 22.83 ? 274 GLN A CD 1 ATOM 2107 O OE1 . GLN A 1 274 ? 3.468 4.488 35.554 1.00 24.24 ? 274 GLN A OE1 1 ATOM 2108 N NE2 . GLN A 1 274 ? 5.674 4.352 35.034 1.00 24.23 ? 274 GLN A NE2 1 ATOM 2109 N N . SER A 1 275 ? 2.669 -1.003 36.710 1.00 15.71 ? 275 SER A N 1 ATOM 2110 C CA . SER A 1 275 ? 1.799 -2.043 37.221 1.00 15.64 ? 275 SER A CA 1 ATOM 2111 C C . SER A 1 275 ? 1.525 -1.843 38.709 1.00 15.94 ? 275 SER A C 1 ATOM 2112 O O . SER A 1 275 ? 0.402 -2.061 39.140 1.00 14.66 ? 275 SER A O 1 ATOM 2113 C CB . SER A 1 275 ? 2.381 -3.435 36.974 1.00 15.33 ? 275 SER A CB 1 ATOM 2114 O OG . SER A 1 275 ? 2.515 -3.683 35.609 1.00 15.39 ? 275 SER A OG 1 ATOM 2115 N N . LEU A 1 276 ? 2.551 -1.437 39.482 1.00 16.62 ? 276 LEU A N 1 ATOM 2116 C CA . LEU A 1 276 ? 2.375 -1.176 40.951 1.00 17.26 ? 276 LEU A CA 1 ATOM 2117 C C . LEU A 1 276 ? 1.445 -0.010 41.313 1.00 17.14 ? 276 LEU A C 1 ATOM 2118 O O . LEU A 1 276 ? 0.571 -0.158 42.210 1.00 17.05 ? 276 LEU A O 1 ATOM 2119 C CB . LEU A 1 276 ? 3.712 -0.926 41.654 1.00 17.47 ? 276 LEU A CB 1 ATOM 2120 C CG . LEU A 1 276 ? 4.610 -2.131 41.936 1.00 18.61 ? 276 LEU A CG 1 ATOM 2121 C CD1 . LEU A 1 276 ? 5.982 -1.618 42.332 1.00 15.04 ? 276 LEU A CD1 1 ATOM 2122 C CD2 . LEU A 1 276 ? 3.997 -2.983 43.047 1.00 20.17 ? 276 LEU A CD2 1 ATOM 2123 N N . LYS A 1 277 ? 1.661 1.134 40.657 1.00 15.94 ? 277 LYS A N 1 ATOM 2124 C CA . LYS A 1 277 ? 0.753 2.270 40.787 1.00 16.69 ? 277 LYS A CA 1 ATOM 2125 C C . LYS A 1 277 ? -0.718 1.804 40.585 1.00 16.90 ? 277 LYS A C 1 ATOM 2126 O O . LYS A 1 277 ? -1.585 2.094 41.422 1.00 16.38 ? 277 LYS A O 1 ATOM 2127 C CB . LYS A 1 277 ? 1.069 3.394 39.787 1.00 17.03 ? 277 LYS A CB 1 ATOM 2128 C CG . LYS A 1 277 ? 2.469 4.094 39.802 1.00 18.12 ? 277 LYS A CG 1 ATOM 2129 C CD . LYS A 1 277 ? 2.212 5.590 39.287 1.00 20.81 ? 277 LYS A CD 1 ATOM 2130 C CE . LYS A 1 277 ? 3.417 6.238 38.564 1.00 26.37 ? 277 LYS A CE 1 ATOM 2131 N NZ . LYS A 1 277 ? 3.187 7.150 37.333 1.00 25.03 ? 277 LYS A NZ 1 ATOM 2132 N N . LYS A 1 278 ? -0.980 1.058 39.493 1.00 16.88 ? 278 LYS A N 1 ATOM 2133 C CA . LYS A 1 278 ? -2.327 0.554 39.199 1.00 16.56 ? 278 LYS A CA 1 ATOM 2134 C C . LYS A 1 278 ? -2.786 -0.509 40.191 1.00 17.25 ? 278 LYS A C 1 ATOM 2135 O O . LYS A 1 278 ? -3.885 -0.377 40.760 1.00 17.28 ? 278 LYS A O 1 ATOM 2136 C CB . LYS A 1 278 ? -2.490 0.103 37.729 1.00 16.36 ? 278 LYS A CB 1 ATOM 2137 C CG . LYS A 1 278 ? -2.238 1.243 36.681 1.00 16.87 ? 278 LYS A CG 1 ATOM 2138 C CD . LYS A 1 278 ? -2.820 2.614 37.108 1.00 15.08 ? 278 LYS A CD 1 ATOM 2139 C CE . LYS A 1 278 ? -2.846 3.620 35.954 1.00 15.42 ? 278 LYS A CE 1 ATOM 2140 N NZ . LYS A 1 278 ? -3.604 4.885 36.325 1.00 13.25 ? 278 LYS A NZ 1 ATOM 2141 N N . TYR A 1 279 ? -1.952 -1.522 40.459 1.00 17.22 ? 279 TYR A N 1 ATOM 2142 C CA . TYR A 1 279 ? -2.346 -2.559 41.421 1.00 17.93 ? 279 TYR A CA 1 ATOM 2143 C C . TYR A 1 279 ? -2.700 -2.078 42.823 1.00 18.42 ? 279 TYR A C 1 ATOM 2144 O O . TYR A 1 279 ? -3.715 -2.554 43.413 1.00 18.69 ? 279 TYR A O 1 ATOM 2145 C CB . TYR A 1 279 ? -1.283 -3.642 41.525 1.00 18.28 ? 279 TYR A CB 1 ATOM 2146 C CG . TYR A 1 279 ? -1.708 -4.845 42.326 1.00 19.52 ? 279 TYR A CG 1 ATOM 2147 C CD1 . TYR A 1 279 ? -2.518 -5.841 41.767 1.00 21.63 ? 279 TYR A CD1 1 ATOM 2148 C CD2 . TYR A 1 279 ? -1.296 -5.002 43.642 1.00 20.63 ? 279 TYR A CD2 1 ATOM 2149 C CE1 . TYR A 1 279 ? -2.908 -6.966 42.517 1.00 21.88 ? 279 TYR A CE1 1 ATOM 2150 C CE2 . TYR A 1 279 ? -1.678 -6.118 44.392 1.00 21.24 ? 279 TYR A CE2 1 ATOM 2151 C CZ . TYR A 1 279 ? -2.474 -7.099 43.838 1.00 22.32 ? 279 TYR A CZ 1 ATOM 2152 O OH . TYR A 1 279 ? -2.834 -8.193 44.617 1.00 22.33 ? 279 TYR A OH 1 ATOM 2153 N N . TYR A 1 280 ? -1.858 -1.189 43.377 1.00 18.33 ? 280 TYR A N 1 ATOM 2154 C CA . TYR A 1 280 ? -2.064 -0.689 44.743 1.00 17.94 ? 280 TYR A CA 1 ATOM 2155 C C . TYR A 1 280 ? -2.958 0.556 44.761 1.00 18.48 ? 280 TYR A C 1 ATOM 2156 O O . TYR A 1 280 ? -3.482 0.910 45.804 1.00 18.53 ? 280 TYR A O 1 ATOM 2157 C CB . TYR A 1 280 ? -0.729 -0.514 45.526 1.00 17.63 ? 280 TYR A CB 1 ATOM 2158 C CG . TYR A 1 280 ? -0.106 -1.854 45.881 1.00 15.06 ? 280 TYR A CG 1 ATOM 2159 C CD1 . TYR A 1 280 ? -0.665 -2.674 46.878 1.00 14.07 ? 280 TYR A CD1 1 ATOM 2160 C CD2 . TYR A 1 280 ? 1.026 -2.341 45.178 1.00 14.06 ? 280 TYR A CD2 1 ATOM 2161 C CE1 . TYR A 1 280 ? -0.109 -3.984 47.170 1.00 13.75 ? 280 TYR A CE1 1 ATOM 2162 C CE2 . TYR A 1 280 ? 1.585 -3.624 45.443 1.00 10.21 ? 280 TYR A CE2 1 ATOM 2163 C CZ . TYR A 1 280 ? 1.027 -4.444 46.447 1.00 13.91 ? 280 TYR A CZ 1 ATOM 2164 O OH . TYR A 1 280 ? 1.581 -5.728 46.672 1.00 11.18 ? 280 TYR A OH 1 ATOM 2165 N N . GLY A 1 281 ? -3.146 1.206 43.608 1.00 18.37 ? 281 GLY A N 1 ATOM 2166 C CA . GLY A 1 281 ? -4.016 2.384 43.514 1.00 17.45 ? 281 GLY A CA 1 ATOM 2167 C C . GLY A 1 281 ? -5.489 2.007 43.402 1.00 18.02 ? 281 GLY A C 1 ATOM 2168 O O . GLY A 1 281 ? -6.332 2.599 44.072 1.00 17.14 ? 281 GLY A O 1 ATOM 2169 N N . HIS A 1 282 ? -5.788 0.998 42.568 1.00 18.39 ? 282 HIS A N 1 ATOM 2170 C CA . HIS A 1 282 ? -7.152 0.723 42.143 1.00 18.85 ? 282 HIS A CA 1 ATOM 2171 C C . HIS A 1 282 ? -7.531 -0.767 42.084 1.00 18.87 ? 282 HIS A C 1 ATOM 2172 O O . HIS A 1 282 ? -8.722 -1.140 42.209 1.00 18.66 ? 282 HIS A O 1 ATOM 2173 C CB . HIS A 1 282 ? -7.420 1.440 40.820 1.00 18.71 ? 282 HIS A CB 1 ATOM 2174 C CG . HIS A 1 282 ? -7.308 2.919 40.931 1.00 20.27 ? 282 HIS A CG 1 ATOM 2175 N ND1 . HIS A 1 282 ? -8.389 3.727 41.243 1.00 21.47 ? 282 HIS A ND1 1 ATOM 2176 C CD2 . HIS A 1 282 ? -6.236 3.736 40.827 1.00 21.56 ? 282 HIS A CD2 1 ATOM 2177 C CE1 . HIS A 1 282 ? -7.982 4.981 41.313 1.00 22.75 ? 282 HIS A CE1 1 ATOM 2178 N NE2 . HIS A 1 282 ? -6.681 5.013 41.070 1.00 25.14 ? 282 HIS A NE2 1 ATOM 2179 N N . GLY A 1 283 ? -6.529 -1.606 41.931 1.00 17.81 ? 283 GLY A N 1 ATOM 2180 C CA . GLY A 1 283 ? -6.753 -3.038 41.947 1.00 17.43 ? 283 GLY A CA 1 ATOM 2181 C C . GLY A 1 283 ? -6.760 -3.643 43.339 1.00 17.49 ? 283 GLY A C 1 ATOM 2182 O O . GLY A 1 283 ? -7.051 -2.952 44.322 1.00 17.43 ? 283 GLY A O 1 ATOM 2183 N N . ALA A 1 284 ? -6.464 -4.950 43.395 1.00 17.40 ? 284 ALA A N 1 ATOM 2184 C CA . ALA A 1 284 ? -6.578 -5.785 44.592 1.00 17.48 ? 284 ALA A CA 1 ATOM 2185 C C . ALA A 1 284 ? -5.671 -5.387 45.720 1.00 17.62 ? 284 ALA A C 1 ATOM 2186 O O . ALA A 1 284 ? -5.999 -5.617 46.893 1.00 17.68 ? 284 ALA A O 1 ATOM 2187 C CB . ALA A 1 284 ? -6.347 -7.259 44.260 1.00 17.46 ? 284 ALA A CB 1 ATOM 2188 N N . GLY A 1 285 ? -4.505 -4.857 45.391 1.00 17.29 ? 285 GLY A N 1 ATOM 2189 C CA . GLY A 1 285 ? -3.618 -4.424 46.433 1.00 17.55 ? 285 GLY A CA 1 ATOM 2190 C C . GLY A 1 285 ? -4.121 -3.277 47.294 1.00 17.48 ? 285 GLY A C 1 ATOM 2191 O O . GLY A 1 285 ? -3.506 -2.974 48.315 1.00 17.74 ? 285 GLY A O 1 ATOM 2192 N N . ASN A 1 286 ? -5.204 -2.617 46.873 1.00 16.96 ? 286 ASN A N 1 ATOM 2193 C CA . ASN A 1 286 ? -5.788 -1.537 47.644 1.00 16.63 ? 286 ASN A CA 1 ATOM 2194 C C . ASN A 1 286 ? -7.117 -1.990 48.268 1.00 17.29 ? 286 ASN A C 1 ATOM 2195 O O . ASN A 1 286 ? -7.988 -2.457 47.580 1.00 16.54 ? 286 ASN A O 1 ATOM 2196 C CB . ASN A 1 286 ? -6.028 -0.362 46.745 1.00 15.65 ? 286 ASN A CB 1 ATOM 2197 C CG . ASN A 1 286 ? -6.502 0.802 47.488 1.00 17.60 ? 286 ASN A CG 1 ATOM 2198 O OD1 . ASN A 1 286 ? -7.637 0.832 48.012 1.00 22.76 ? 286 ASN A OD1 1 ATOM 2199 N ND2 . ASN A 1 286 ? -5.650 1.794 47.582 1.00 13.75 ? 286 ASN A ND2 1 ATOM 2200 N N . PRO A 1 287 ? -7.281 -1.821 49.579 1.00 18.20 ? 287 PRO A N 1 ATOM 2201 C CA . PRO A 1 287 ? -8.426 -2.471 50.233 1.00 18.47 ? 287 PRO A CA 1 ATOM 2202 C C . PRO A 1 287 ? -9.778 -2.088 49.661 1.00 18.25 ? 287 PRO A C 1 ATOM 2203 O O . PRO A 1 287 ? -10.700 -2.862 49.763 1.00 19.03 ? 287 PRO A O 1 ATOM 2204 C CB . PRO A 1 287 ? -8.352 -1.991 51.685 1.00 18.06 ? 287 PRO A CB 1 ATOM 2205 C CG . PRO A 1 287 ? -7.409 -0.830 51.688 1.00 19.27 ? 287 PRO A CG 1 ATOM 2206 C CD . PRO A 1 287 ? -6.557 -0.874 50.455 1.00 18.28 ? 287 PRO A CD 1 ATOM 2207 N N . LEU A 1 288 ? -9.875 -0.906 49.070 1.00 18.13 ? 288 LEU A N 1 ATOM 2208 C CA . LEU A 1 288 ? -11.123 -0.367 48.551 1.00 16.98 ? 288 LEU A CA 1 ATOM 2209 C C . LEU A 1 288 ? -11.136 -0.284 47.027 1.00 16.68 ? 288 LEU A C 1 ATOM 2210 O O . LEU A 1 288 ? -12.096 0.200 46.432 1.00 17.67 ? 288 LEU A O 1 ATOM 2211 C CB . LEU A 1 288 ? -11.314 1.028 49.141 1.00 17.47 ? 288 LEU A CB 1 ATOM 2212 C CG . LEU A 1 288 ? -12.026 1.037 50.506 1.00 19.58 ? 288 LEU A CG 1 ATOM 2213 C CD1 . LEU A 1 288 ? -12.069 2.425 51.141 1.00 19.35 ? 288 LEU A CD1 1 ATOM 2214 C CD2 . LEU A 1 288 ? -13.459 0.473 50.352 1.00 21.53 ? 288 LEU A CD2 1 ATOM 2215 N N . GLY A 1 289 ? -10.057 -0.742 46.393 1.00 15.57 ? 289 GLY A N 1 ATOM 2216 C CA . GLY A 1 289 ? -9.908 -0.676 44.961 1.00 14.10 ? 289 GLY A CA 1 ATOM 2217 C C . GLY A 1 289 ? -10.943 -1.462 44.168 1.00 13.15 ? 289 GLY A C 1 ATOM 2218 O O . GLY A 1 289 ? -11.652 -0.865 43.376 1.00 12.20 ? 289 GLY A O 1 ATOM 2219 N N . PRO A 1 290 ? -11.012 -2.810 44.355 1.00 12.57 ? 290 PRO A N 1 ATOM 2220 C CA . PRO A 1 290 ? -12.033 -3.611 43.640 1.00 12.20 ? 290 PRO A CA 1 ATOM 2221 C C . PRO A 1 290 ? -13.466 -3.127 44.035 1.00 13.51 ? 290 PRO A C 1 ATOM 2222 O O . PRO A 1 290 ? -14.463 -3.386 43.313 1.00 11.96 ? 290 PRO A O 1 ATOM 2223 C CB . PRO A 1 290 ? -11.810 -5.054 44.158 1.00 11.54 ? 290 PRO A CB 1 ATOM 2224 C CG . PRO A 1 290 ? -10.445 -5.079 44.847 1.00 12.34 ? 290 PRO A CG 1 ATOM 2225 C CD . PRO A 1 290 ? -10.218 -3.617 45.307 1.00 12.45 ? 290 PRO A CD 1 ATOM 2226 N N . THR A 1 291 ? -13.568 -2.419 45.164 1.00 13.45 ? 291 THR A N 1 ATOM 2227 C CA . THR A 1 291 ? -14.870 -1.963 45.581 1.00 14.66 ? 291 THR A CA 1 ATOM 2228 C C . THR A 1 291 ? -15.265 -0.803 44.666 1.00 15.50 ? 291 THR A C 1 ATOM 2229 O O . THR A 1 291 ? -16.450 -0.484 44.499 1.00 16.41 ? 291 THR A O 1 ATOM 2230 C CB . THR A 1 291 ? -14.881 -1.545 47.056 1.00 14.65 ? 291 THR A CB 1 ATOM 2231 O OG1 . THR A 1 291 ? -15.245 -2.684 47.871 1.00 14.26 ? 291 THR A OG1 1 ATOM 2232 C CG2 . THR A 1 291 ? -15.822 -0.372 47.261 1.00 11.40 ? 291 THR A CG2 1 ATOM 2233 N N . GLN A 1 292 ? -14.274 -0.171 44.060 1.00 15.24 ? 292 GLN A N 1 ATOM 2234 C CA . GLN A 1 292 ? -14.591 0.861 43.059 1.00 15.63 ? 292 GLN A CA 1 ATOM 2235 C C . GLN A 1 292 ? -15.283 0.232 41.824 1.00 15.25 ? 292 GLN A C 1 ATOM 2236 O O . GLN A 1 292 ? -16.004 0.903 41.132 1.00 14.06 ? 292 GLN A O 1 ATOM 2237 C CB . GLN A 1 292 ? -13.340 1.688 42.690 1.00 15.65 ? 292 GLN A CB 1 ATOM 2238 C CG . GLN A 1 292 ? -12.709 2.409 43.908 1.00 14.68 ? 292 GLN A CG 1 ATOM 2239 C CD . GLN A 1 292 ? -13.778 3.128 44.753 1.00 14.11 ? 292 GLN A CD 1 ATOM 2240 O OE1 . GLN A 1 292 ? -14.338 4.154 44.334 1.00 15.53 ? 292 GLN A OE1 1 ATOM 2241 N NE2 . GLN A 1 292 ? -14.038 2.607 45.949 1.00 9.47 ? 292 GLN A NE2 1 ATOM 2242 N N . GLY A 1 293 ? -15.110 -1.079 41.608 1.00 15.75 ? 293 GLY A N 1 ATOM 2243 C CA . GLY A 1 293 ? -15.698 -1.749 40.443 1.00 15.44 ? 293 GLY A CA 1 ATOM 2244 C C . GLY A 1 293 ? -17.069 -2.397 40.649 1.00 15.60 ? 293 GLY A C 1 ATOM 2245 O O . GLY A 1 293 ? -17.625 -3.009 39.733 1.00 15.31 ? 293 GLY A O 1 ATOM 2246 N N . VAL A 1 294 ? -17.621 -2.339 41.851 1.00 16.05 ? 294 VAL A N 1 ATOM 2247 C CA . VAL A 1 294 ? -18.781 -3.184 42.059 1.00 16.14 ? 294 VAL A CA 1 ATOM 2248 C C . VAL A 1 294 ? -20.046 -2.676 41.385 1.00 14.78 ? 294 VAL A C 1 ATOM 2249 O O . VAL A 1 294 ? -20.830 -3.472 40.960 1.00 14.83 ? 294 VAL A O 1 ATOM 2250 C CB . VAL A 1 294 ? -18.953 -3.755 43.530 1.00 16.84 ? 294 VAL A CB 1 ATOM 2251 C CG1 . VAL A 1 294 ? -17.661 -3.617 44.293 1.00 17.48 ? 294 VAL A CG1 1 ATOM 2252 C CG2 . VAL A 1 294 ? -20.176 -3.154 44.249 1.00 15.49 ? 294 VAL A CG2 1 ATOM 2253 N N . GLY A 1 295 ? -20.158 -1.363 41.203 1.00 15.12 ? 295 GLY A N 1 ATOM 2254 C CA . GLY A 1 295 ? -21.268 -0.733 40.500 1.00 13.99 ? 295 GLY A CA 1 ATOM 2255 C C . GLY A 1 295 ? -21.392 -1.235 39.071 1.00 14.08 ? 295 GLY A C 1 ATOM 2256 O O . GLY A 1 295 ? -22.499 -1.618 38.638 1.00 14.82 ? 295 GLY A O 1 ATOM 2257 N N . TYR A 1 296 ? -20.272 -1.250 38.344 1.00 12.37 ? 296 TYR A N 1 ATOM 2258 C CA . TYR A 1 296 ? -20.245 -1.679 36.998 1.00 11.93 ? 296 TYR A CA 1 ATOM 2259 C C . TYR A 1 296 ? -20.474 -3.165 36.889 1.00 12.55 ? 296 TYR A C 1 ATOM 2260 O O . TYR A 1 296 ? -21.118 -3.612 35.958 1.00 13.87 ? 296 TYR A O 1 ATOM 2261 C CB . TYR A 1 296 ? -18.882 -1.331 36.350 1.00 13.13 ? 296 TYR A CB 1 ATOM 2262 C CG . TYR A 1 296 ? -18.904 -1.436 34.835 1.00 12.56 ? 296 TYR A CG 1 ATOM 2263 C CD1 . TYR A 1 296 ? -19.411 -0.402 34.042 1.00 14.28 ? 296 TYR A CD1 1 ATOM 2264 C CD2 . TYR A 1 296 ? -18.479 -2.602 34.200 1.00 16.09 ? 296 TYR A CD2 1 ATOM 2265 C CE1 . TYR A 1 296 ? -19.422 -0.519 32.639 1.00 17.27 ? 296 TYR A CE1 1 ATOM 2266 C CE2 . TYR A 1 296 ? -18.471 -2.726 32.814 1.00 16.80 ? 296 TYR A CE2 1 ATOM 2267 C CZ . TYR A 1 296 ? -18.933 -1.688 32.033 1.00 19.09 ? 296 TYR A CZ 1 ATOM 2268 O OH . TYR A 1 296 ? -18.957 -1.853 30.649 1.00 20.41 ? 296 TYR A OH 1 ATOM 2269 N N . ALA A 1 297 ? -19.899 -3.937 37.799 1.00 12.44 ? 297 ALA A N 1 ATOM 2270 C CA . ALA A 1 297 ? -20.096 -5.361 37.861 1.00 13.10 ? 297 ALA A CA 1 ATOM 2271 C C . ALA A 1 297 ? -21.574 -5.653 38.049 1.00 14.00 ? 297 ALA A C 1 ATOM 2272 O O . ALA A 1 297 ? -22.046 -6.611 37.501 1.00 14.71 ? 297 ALA A O 1 ATOM 2273 C CB . ALA A 1 297 ? -19.280 -5.990 39.012 1.00 11.77 ? 297 ALA A CB 1 ATOM 2274 N N . ASN A 1 298 ? -22.309 -4.848 38.817 1.00 14.90 ? 298 ASN A N 1 ATOM 2275 C CA . ASN A 1 298 ? -23.740 -5.158 39.018 1.00 16.10 ? 298 ASN A CA 1 ATOM 2276 C C . ASN A 1 298 ? -24.544 -4.768 37.789 1.00 17.05 ? 298 ASN A C 1 ATOM 2277 O O . ASN A 1 298 ? -25.540 -5.439 37.475 1.00 17.98 ? 298 ASN A O 1 ATOM 2278 C CB . ASN A 1 298 ? -24.332 -4.512 40.285 1.00 15.88 ? 298 ASN A CB 1 ATOM 2279 C CG . ASN A 1 298 ? -23.822 -5.154 41.565 1.00 17.39 ? 298 ASN A CG 1 ATOM 2280 O OD1 . ASN A 1 298 ? -23.880 -6.411 41.759 1.00 15.09 ? 298 ASN A OD1 1 ATOM 2281 N ND2 . ASN A 1 298 ? -23.308 -4.302 42.461 1.00 15.39 ? 298 ASN A ND2 1 ATOM 2282 N N . GLU A 1 299 ? -24.118 -3.706 37.088 1.00 16.31 ? 299 GLU A N 1 ATOM 2283 C CA . GLU A 1 299 ? -24.731 -3.369 35.784 1.00 16.05 ? 299 GLU A CA 1 ATOM 2284 C C . GLU A 1 299 ? -24.479 -4.462 34.740 1.00 16.46 ? 299 GLU A C 1 ATOM 2285 O O . GLU A 1 299 ? -25.389 -4.904 34.059 1.00 15.89 ? 299 GLU A O 1 ATOM 2286 C CB . GLU A 1 299 ? -24.226 -2.031 35.285 1.00 15.50 ? 299 GLU A CB 1 ATOM 2287 C CG . GLU A 1 299 ? -24.715 -0.914 36.153 1.00 14.57 ? 299 GLU A CG 1 ATOM 2288 C CD . GLU A 1 299 ? -24.261 0.426 35.671 1.00 16.65 ? 299 GLU A CD 1 ATOM 2289 O OE1 . GLU A 1 299 ? -23.128 0.504 35.168 1.00 16.56 ? 299 GLU A OE1 1 ATOM 2290 O OE2 . GLU A 1 299 ? -25.055 1.385 35.750 1.00 18.19 ? 299 GLU A OE2 1 ATOM 2291 N N . LEU A 1 300 ? -23.247 -4.943 34.634 1.00 17.12 ? 300 LEU A N 1 ATOM 2292 C CA . LEU A 1 300 ? -23.044 -6.099 33.754 1.00 17.45 ? 300 LEU A CA 1 ATOM 2293 C C . LEU A 1 300 ? -23.979 -7.284 34.136 1.00 17.41 ? 300 LEU A C 1 ATOM 2294 O O . LEU A 1 300 ? -24.580 -7.903 33.256 1.00 19.01 ? 300 LEU A O 1 ATOM 2295 C CB . LEU A 1 300 ? -21.589 -6.531 33.728 1.00 17.04 ? 300 LEU A CB 1 ATOM 2296 C CG . LEU A 1 300 ? -21.376 -7.827 32.935 1.00 16.76 ? 300 LEU A CG 1 ATOM 2297 C CD1 . LEU A 1 300 ? -21.442 -7.534 31.456 1.00 15.65 ? 300 LEU A CD1 1 ATOM 2298 C CD2 . LEU A 1 300 ? -19.972 -8.457 33.275 1.00 14.75 ? 300 LEU A CD2 1 ATOM 2299 N N . ILE A 1 301 ? -24.125 -7.577 35.420 1.00 16.88 ? 301 ILE A N 1 ATOM 2300 C CA . ILE A 1 301 ? -24.988 -8.677 35.852 1.00 17.23 ? 301 ILE A CA 1 ATOM 2301 C C . ILE A 1 301 ? -26.436 -8.465 35.361 1.00 17.26 ? 301 ILE A C 1 ATOM 2302 O O . ILE A 1 301 ? -27.023 -9.353 34.758 1.00 18.13 ? 301 ILE A O 1 ATOM 2303 C CB . ILE A 1 301 ? -24.889 -8.905 37.384 1.00 17.20 ? 301 ILE A CB 1 ATOM 2304 C CG1 . ILE A 1 301 ? -23.667 -9.706 37.744 1.00 15.94 ? 301 ILE A CG1 1 ATOM 2305 C CG2 . ILE A 1 301 ? -26.155 -9.581 37.985 1.00 16.73 ? 301 ILE A CG2 1 ATOM 2306 C CD1 . ILE A 1 301 ? -23.342 -9.531 39.214 1.00 18.99 ? 301 ILE A CD1 1 ATOM 2307 N N . ALA A 1 302 ? -26.980 -7.276 35.586 1.00 17.48 ? 302 ALA A N 1 ATOM 2308 C CA . ALA A 1 302 ? -28.265 -6.855 35.007 1.00 17.69 ? 302 ALA A CA 1 ATOM 2309 C C . ALA A 1 302 ? -28.406 -7.188 33.526 1.00 18.13 ? 302 ALA A C 1 ATOM 2310 O O . ALA A 1 302 ? -29.378 -7.806 33.072 1.00 17.59 ? 302 ALA A O 1 ATOM 2311 C CB . ALA A 1 302 ? -28.436 -5.354 35.200 1.00 17.39 ? 302 ALA A CB 1 ATOM 2312 N N . ARG A 1 303 ? -27.394 -6.774 32.781 1.00 19.15 ? 303 ARG A N 1 ATOM 2313 C CA . ARG A 1 303 ? -27.347 -7.003 31.352 1.00 18.84 ? 303 ARG A CA 1 ATOM 2314 C C . ARG A 1 303 ? -27.269 -8.483 30.999 1.00 19.56 ? 303 ARG A C 1 ATOM 2315 O O . ARG A 1 303 ? -27.945 -8.927 30.093 1.00 20.46 ? 303 ARG A O 1 ATOM 2316 C CB . ARG A 1 303 ? -26.207 -6.216 30.730 1.00 18.25 ? 303 ARG A CB 1 ATOM 2317 C CG . ARG A 1 303 ? -26.464 -4.744 30.784 1.00 15.33 ? 303 ARG A CG 1 ATOM 2318 C CD . ARG A 1 303 ? -25.299 -3.935 30.247 1.00 13.01 ? 303 ARG A CD 1 ATOM 2319 N NE . ARG A 1 303 ? -25.678 -2.527 30.087 1.00 11.71 ? 303 ARG A NE 1 ATOM 2320 C CZ . ARG A 1 303 ? -24.828 -1.521 29.842 1.00 14.52 ? 303 ARG A CZ 1 ATOM 2321 N NH1 . ARG A 1 303 ? -23.513 -1.759 29.706 1.00 15.22 ? 303 ARG A NH1 1 ATOM 2322 N NH2 . ARG A 1 303 ? -25.293 -0.279 29.666 1.00 8.64 ? 303 ARG A NH2 1 ATOM 2323 N N . LEU A 1 304 ? -26.468 -9.257 31.718 1.00 20.46 ? 304 LEU A N 1 ATOM 2324 C CA . LEU A 1 304 ? -26.307 -10.642 31.362 1.00 19.81 ? 304 LEU A CA 1 ATOM 2325 C C . LEU A 1 304 ? -27.555 -11.393 31.706 1.00 20.66 ? 304 LEU A C 1 ATOM 2326 O O . LEU A 1 304 ? -27.848 -12.383 31.031 1.00 20.88 ? 304 LEU A O 1 ATOM 2327 C CB . LEU A 1 304 ? -25.147 -11.268 32.092 1.00 19.45 ? 304 LEU A CB 1 ATOM 2328 C CG . LEU A 1 304 ? -23.684 -10.954 31.781 1.00 19.95 ? 304 LEU A CG 1 ATOM 2329 C CD1 . LEU A 1 304 ? -22.838 -11.811 32.701 1.00 16.23 ? 304 LEU A CD1 1 ATOM 2330 C CD2 . LEU A 1 304 ? -23.277 -11.140 30.297 1.00 20.12 ? 304 LEU A CD2 1 ATOM 2331 N N . THR A 1 305 ? -28.265 -10.939 32.756 1.00 20.96 ? 305 THR A N 1 ATOM 2332 C CA . THR A 1 305 ? -29.516 -11.584 33.226 1.00 21.69 ? 305 THR A CA 1 ATOM 2333 C C . THR A 1 305 ? -30.817 -10.885 32.823 1.00 22.46 ? 305 THR A C 1 ATOM 2334 O O . THR A 1 305 ? -31.886 -11.347 33.216 1.00 22.47 ? 305 THR A O 1 ATOM 2335 C CB . THR A 1 305 ? -29.563 -11.712 34.760 1.00 21.43 ? 305 THR A CB 1 ATOM 2336 O OG1 . THR A 1 305 ? -29.253 -10.447 35.339 1.00 22.14 ? 305 THR A OG1 1 ATOM 2337 C CG2 . THR A 1 305 ? -28.582 -12.766 35.288 1.00 21.50 ? 305 THR A CG2 1 ATOM 2338 N N . HIS A 1 306 ? -30.729 -9.768 32.073 1.00 23.47 ? 306 HIS A N 1 ATOM 2339 C CA . HIS A 1 306 ? -31.900 -9.043 31.544 1.00 23.30 ? 306 HIS A CA 1 ATOM 2340 C C . HIS A 1 306 ? -32.886 -8.805 32.663 1.00 24.46 ? 306 HIS A C 1 ATOM 2341 O O . HIS A 1 306 ? -34.120 -9.013 32.492 1.00 23.87 ? 306 HIS A O 1 ATOM 2342 C CB . HIS A 1 306 ? -32.586 -9.821 30.417 1.00 23.32 ? 306 HIS A CB 1 ATOM 2343 C CG . HIS A 1 306 ? -31.632 -10.518 29.494 1.00 24.91 ? 306 HIS A CG 1 ATOM 2344 N ND1 . HIS A 1 306 ? -30.928 -9.859 28.504 1.00 25.72 ? 306 HIS A ND1 1 ATOM 2345 C CD2 . HIS A 1 306 ? -31.255 -11.822 29.422 1.00 25.48 ? 306 HIS A CD2 1 ATOM 2346 C CE1 . HIS A 1 306 ? -30.151 -10.725 27.871 1.00 26.38 ? 306 HIS A CE1 1 ATOM 2347 N NE2 . HIS A 1 306 ? -30.339 -11.925 28.403 1.00 25.32 ? 306 HIS A NE2 1 ATOM 2348 N N . SER A 1 307 ? -32.325 -8.402 33.819 1.00 24.87 ? 307 SER A N 1 ATOM 2349 C CA . SER A 1 307 ? -33.052 -8.134 35.071 1.00 24.75 ? 307 SER A CA 1 ATOM 2350 C C . SER A 1 307 ? -32.618 -6.770 35.579 1.00 24.81 ? 307 SER A C 1 ATOM 2351 O O . SER A 1 307 ? -31.549 -6.300 35.193 1.00 24.37 ? 307 SER A O 1 ATOM 2352 C CB . SER A 1 307 ? -32.661 -9.156 36.155 1.00 24.93 ? 307 SER A CB 1 ATOM 2353 O OG . SER A 1 307 ? -32.945 -10.473 35.739 1.00 25.39 ? 307 SER A OG 1 ATOM 2354 N N . PRO A 1 308 ? -33.417 -6.146 36.473 1.00 25.16 ? 308 PRO A N 1 ATOM 2355 C CA . PRO A 1 308 ? -33.044 -4.876 37.127 1.00 25.86 ? 308 PRO A CA 1 ATOM 2356 C C . PRO A 1 308 ? -31.658 -4.879 37.854 1.00 26.75 ? 308 PRO A C 1 ATOM 2357 O O . PRO A 1 308 ? -31.212 -5.929 38.354 1.00 26.80 ? 308 PRO A O 1 ATOM 2358 C CB . PRO A 1 308 ? -34.162 -4.677 38.158 1.00 26.00 ? 308 PRO A CB 1 ATOM 2359 C CG . PRO A 1 308 ? -35.344 -5.444 37.609 1.00 26.07 ? 308 PRO A CG 1 ATOM 2360 C CD . PRO A 1 308 ? -34.792 -6.576 36.822 1.00 25.26 ? 308 PRO A CD 1 ATOM 2361 N N . VAL A 1 309 ? -31.018 -3.706 37.932 1.00 27.02 ? 309 VAL A N 1 ATOM 2362 C CA . VAL A 1 309 ? -29.727 -3.558 38.565 1.00 27.31 ? 309 VAL A CA 1 ATOM 2363 C C . VAL A 1 309 ? -29.969 -3.693 40.038 1.00 28.47 ? 309 VAL A C 1 ATOM 2364 O O . VAL A 1 309 ? -30.912 -3.084 40.555 1.00 28.99 ? 309 VAL A O 1 ATOM 2365 C CB . VAL A 1 309 ? -29.105 -2.173 38.295 1.00 27.39 ? 309 VAL A CB 1 ATOM 2366 C CG1 . VAL A 1 309 ? -27.688 -2.125 38.804 1.00 25.45 ? 309 VAL A CG1 1 ATOM 2367 C CG2 . VAL A 1 309 ? -29.129 -1.858 36.813 1.00 26.31 ? 309 VAL A CG2 1 ATOM 2368 N N . HIS A 1 310 ? -29.153 -4.521 40.702 1.00 29.05 ? 310 HIS A N 1 ATOM 2369 C CA . HIS A 1 310 ? -29.117 -4.578 42.166 1.00 29.78 ? 310 HIS A CA 1 ATOM 2370 C C . HIS A 1 310 ? -27.770 -4.054 42.648 1.00 29.13 ? 310 HIS A C 1 ATOM 2371 O O . HIS A 1 310 ? -26.729 -4.723 42.550 1.00 29.43 ? 310 HIS A O 1 ATOM 2372 C CB . HIS A 1 310 ? -29.475 -5.972 42.692 1.00 30.11 ? 310 HIS A CB 1 ATOM 2373 C CG . HIS A 1 310 ? -30.801 -6.452 42.179 1.00 35.19 ? 310 HIS A CG 1 ATOM 2374 N ND1 . HIS A 1 310 ? -30.930 -7.551 41.349 1.00 38.25 ? 310 HIS A ND1 1 ATOM 2375 C CD2 . HIS A 1 310 ? -32.048 -5.926 42.306 1.00 37.58 ? 310 HIS A CD2 1 ATOM 2376 C CE1 . HIS A 1 310 ? -32.203 -7.700 41.012 1.00 39.32 ? 310 HIS A CE1 1 ATOM 2377 N NE2 . HIS A 1 310 ? -32.902 -6.726 41.577 1.00 39.68 ? 310 HIS A NE2 1 ATOM 2378 N N . ASP A 1 311 ? -27.807 -2.811 43.111 1.00 28.32 ? 311 ASP A N 1 ATOM 2379 C CA . ASP A 1 311 ? -26.613 -2.090 43.462 1.00 28.03 ? 311 ASP A CA 1 ATOM 2380 C C . ASP A 1 311 ? -26.912 -0.865 44.285 1.00 27.90 ? 311 ASP A C 1 ATOM 2381 O O . ASP A 1 311 ? -27.771 -0.053 43.958 1.00 28.49 ? 311 ASP A O 1 ATOM 2382 C CB . ASP A 1 311 ? -25.857 -1.659 42.208 1.00 27.77 ? 311 ASP A CB 1 ATOM 2383 C CG . ASP A 1 311 ? -24.616 -0.865 42.529 1.00 27.50 ? 311 ASP A CG 1 ATOM 2384 O OD1 . ASP A 1 311 ? -23.557 -1.478 42.813 1.00 28.34 ? 311 ASP A OD1 1 ATOM 2385 O OD2 . ASP A 1 311 ? -24.708 0.376 42.494 1.00 27.10 ? 311 ASP A OD2 1 ATOM 2386 N N . ASP A 1 312 ? -26.126 -0.695 45.321 1.00 28.02 ? 312 ASP A N 1 ATOM 2387 C CA . ASP A 1 312 ? -26.336 0.383 46.231 1.00 28.32 ? 312 ASP A CA 1 ATOM 2388 C C . ASP A 1 312 ? -24.998 1.113 46.487 1.00 26.80 ? 312 ASP A C 1 ATOM 2389 O O . ASP A 1 312 ? -24.880 1.931 47.398 1.00 26.75 ? 312 ASP A O 1 ATOM 2390 C CB . ASP A 1 312 ? -26.999 -0.228 47.460 1.00 29.50 ? 312 ASP A CB 1 ATOM 2391 C CG . ASP A 1 312 ? -27.478 0.776 48.415 1.00 34.35 ? 312 ASP A CG 1 ATOM 2392 O OD1 . ASP A 1 312 ? -28.092 1.782 47.966 1.00 39.38 ? 312 ASP A OD1 1 ATOM 2393 O OD2 . ASP A 1 312 ? -27.248 0.541 49.636 1.00 40.37 ? 312 ASP A OD2 1 ATOM 2394 N N . THR A 1 313 ? -24.026 0.861 45.608 1.00 25.04 ? 313 THR A N 1 ATOM 2395 C CA . THR A 1 313 ? -22.722 1.510 45.658 1.00 23.12 ? 313 THR A CA 1 ATOM 2396 C C . THR A 1 313 ? -22.576 2.762 44.741 1.00 24.02 ? 313 THR A C 1 ATOM 2397 O O . THR A 1 313 ? -22.906 3.900 45.131 1.00 23.75 ? 313 THR A O 1 ATOM 2398 C CB . THR A 1 313 ? -21.577 0.464 45.409 1.00 22.94 ? 313 THR A CB 1 ATOM 2399 O OG1 . THR A 1 313 ? -21.348 0.246 43.999 1.00 17.20 ? 313 THR A OG1 1 ATOM 2400 C CG2 . THR A 1 313 ? -21.900 -0.853 46.124 1.00 21.24 ? 313 THR A CG2 1 ATOM 2401 N N . SER A 1 314 ? -22.100 2.545 43.513 1.00 24.17 ? 314 SER A N 1 ATOM 2402 C CA . SER A 1 314 ? -21.710 3.627 42.616 1.00 23.70 ? 314 SER A CA 1 ATOM 2403 C C . SER A 1 314 ? -22.703 3.911 41.491 1.00 24.13 ? 314 SER A C 1 ATOM 2404 O O . SER A 1 314 ? -22.517 4.875 40.750 1.00 24.08 ? 314 SER A O 1 ATOM 2405 C CB . SER A 1 314 ? -20.337 3.343 42.008 1.00 23.36 ? 314 SER A CB 1 ATOM 2406 O OG . SER A 1 314 ? -20.440 2.304 41.048 1.00 22.91 ? 314 SER A OG 1 ATOM 2407 N N . SER A 1 315 ? -23.729 3.072 41.330 1.00 24.51 ? 315 SER A N 1 ATOM 2408 C CA . SER A 1 315 ? -24.724 3.286 40.259 1.00 25.34 ? 315 SER A CA 1 ATOM 2409 C C . SER A 1 315 ? -25.688 4.434 40.537 1.00 25.84 ? 315 SER A C 1 ATOM 2410 O O . SER A 1 315 ? -26.068 4.659 41.667 1.00 26.84 ? 315 SER A O 1 ATOM 2411 C CB . SER A 1 315 ? -25.504 2.004 39.955 1.00 24.58 ? 315 SER A CB 1 ATOM 2412 O OG . SER A 1 315 ? -26.300 1.606 41.052 1.00 27.03 ? 315 SER A OG 1 ATOM 2413 N N . ASN A 1 316 ? -26.053 5.166 39.506 1.00 26.46 ? 316 ASN A N 1 ATOM 2414 C CA . ASN A 1 316 ? -27.119 6.137 39.594 1.00 27.53 ? 316 ASN A CA 1 ATOM 2415 C C . ASN A 1 316 ? -28.469 5.443 39.332 1.00 27.71 ? 316 ASN A C 1 ATOM 2416 O O . ASN A 1 316 ? -28.653 4.818 38.280 1.00 28.54 ? 316 ASN A O 1 ATOM 2417 C CB . ASN A 1 316 ? -26.854 7.243 38.577 1.00 27.39 ? 316 ASN A CB 1 ATOM 2418 C CG . ASN A 1 316 ? -27.919 8.329 38.577 1.00 29.54 ? 316 ASN A CG 1 ATOM 2419 O OD1 . ASN A 1 316 ? -29.127 8.073 38.811 1.00 29.58 ? 316 ASN A OD1 1 ATOM 2420 N ND2 . ASN A 1 316 ? -27.473 9.562 38.309 1.00 30.32 ? 316 ASN A ND2 1 ATOM 2421 N N . HIS A 1 317 ? -29.410 5.582 40.267 1.00 27.94 ? 317 HIS A N 1 ATOM 2422 C CA . HIS A 1 317 ? -30.703 4.869 40.240 1.00 27.72 ? 317 HIS A CA 1 ATOM 2423 C C . HIS A 1 317 ? -31.720 5.448 39.267 1.00 27.27 ? 317 HIS A C 1 ATOM 2424 O O . HIS A 1 317 ? -32.534 4.728 38.684 1.00 26.97 ? 317 HIS A O 1 ATOM 2425 C CB . HIS A 1 317 ? -31.301 4.809 41.645 1.00 28.27 ? 317 HIS A CB 1 ATOM 2426 C CG . HIS A 1 317 ? -30.596 3.846 42.548 1.00 30.17 ? 317 HIS A CG 1 ATOM 2427 N ND1 . HIS A 1 317 ? -31.021 2.548 42.729 1.00 34.21 ? 317 HIS A ND1 1 ATOM 2428 C CD2 . HIS A 1 317 ? -29.463 3.971 43.277 1.00 33.07 ? 317 HIS A CD2 1 ATOM 2429 C CE1 . HIS A 1 317 ? -30.198 1.921 43.556 1.00 33.99 ? 317 HIS A CE1 1 ATOM 2430 N NE2 . HIS A 1 317 ? -29.236 2.759 43.890 1.00 34.10 ? 317 HIS A NE2 1 ATOM 2431 N N . THR A 1 318 ? -31.689 6.757 39.117 1.00 26.52 ? 318 THR A N 1 ATOM 2432 C CA . THR A 1 318 ? -32.466 7.410 38.091 1.00 25.89 ? 318 THR A CA 1 ATOM 2433 C C . THR A 1 318 ? -32.038 6.872 36.715 1.00 25.77 ? 318 THR A C 1 ATOM 2434 O O . THR A 1 318 ? -32.884 6.461 35.898 1.00 25.74 ? 318 THR A O 1 ATOM 2435 C CB . THR A 1 318 ? -32.205 8.922 38.112 1.00 26.09 ? 318 THR A CB 1 ATOM 2436 O OG1 . THR A 1 318 ? -32.437 9.440 39.421 1.00 24.83 ? 318 THR A OG1 1 ATOM 2437 C CG2 . THR A 1 318 ? -33.071 9.643 37.074 1.00 25.38 ? 318 THR A CG2 1 ATOM 2438 N N . LEU A 1 319 ? -30.726 6.891 36.463 1.00 25.15 ? 319 LEU A N 1 ATOM 2439 C CA . LEU A 1 319 ? -30.173 6.399 35.209 1.00 24.14 ? 319 LEU A CA 1 ATOM 2440 C C . LEU A 1 319 ? -30.458 4.903 34.996 1.00 24.42 ? 319 LEU A C 1 ATOM 2441 O O . LEU A 1 319 ? -30.863 4.490 33.886 1.00 24.79 ? 319 LEU A O 1 ATOM 2442 C CB . LEU A 1 319 ? -28.692 6.665 35.176 1.00 23.91 ? 319 LEU A CB 1 ATOM 2443 C CG . LEU A 1 319 ? -28.048 7.643 34.200 1.00 23.66 ? 319 LEU A CG 1 ATOM 2444 C CD1 . LEU A 1 319 ? -28.932 8.782 33.799 1.00 24.46 ? 319 LEU A CD1 1 ATOM 2445 C CD2 . LEU A 1 319 ? -26.714 8.144 34.773 1.00 21.53 ? 319 LEU A CD2 1 ATOM 2446 N N . ASP A 1 320 ? -30.298 4.095 36.046 1.00 23.39 ? 320 ASP A N 1 ATOM 2447 C CA . ASP A 1 320 ? -30.472 2.657 35.892 1.00 23.03 ? 320 ASP A CA 1 ATOM 2448 C C . ASP A 1 320 ? -31.867 2.082 35.931 1.00 23.47 ? 320 ASP A C 1 ATOM 2449 O O . ASP A 1 320 ? -32.069 1.025 35.374 1.00 23.66 ? 320 ASP A O 1 ATOM 2450 C CB . ASP A 1 320 ? -29.564 1.857 36.841 1.00 22.61 ? 320 ASP A CB 1 ATOM 2451 C CG . ASP A 1 320 ? -28.134 1.839 36.380 1.00 20.35 ? 320 ASP A CG 1 ATOM 2452 O OD1 . ASP A 1 320 ? -27.749 2.688 35.534 1.00 22.55 ? 320 ASP A OD1 1 ATOM 2453 O OD2 . ASP A 1 320 ? -27.372 0.997 36.861 1.00 16.17 ? 320 ASP A OD2 1 ATOM 2454 N N . SER A 1 321 ? -32.833 2.726 36.567 1.00 24.09 ? 321 SER A N 1 ATOM 2455 C CA . SER A 1 321 ? -34.144 2.063 36.721 1.00 25.39 ? 321 SER A CA 1 ATOM 2456 C C . SER A 1 321 ? -35.094 2.371 35.565 1.00 25.67 ? 321 SER A C 1 ATOM 2457 O O . SER A 1 321 ? -36.285 2.122 35.640 1.00 24.78 ? 321 SER A O 1 ATOM 2458 C CB . SER A 1 321 ? -34.789 2.378 38.090 1.00 25.50 ? 321 SER A CB 1 ATOM 2459 O OG . SER A 1 321 ? -35.245 3.719 38.128 1.00 27.09 ? 321 SER A OG 1 ATOM 2460 N N . SER A 1 322 ? -34.516 2.880 34.475 1.00 26.88 ? 322 SER A N 1 ATOM 2461 C CA . SER A 1 322 ? -35.270 3.380 33.320 1.00 27.08 ? 322 SER A CA 1 ATOM 2462 C C . SER A 1 322 ? -34.757 2.775 32.016 1.00 26.85 ? 322 SER A C 1 ATOM 2463 O O . SER A 1 322 ? -33.577 2.968 31.688 1.00 27.53 ? 322 SER A O 1 ATOM 2464 C CB . SER A 1 322 ? -35.168 4.912 33.293 1.00 27.02 ? 322 SER A CB 1 ATOM 2465 O OG . SER A 1 322 ? -35.146 5.409 31.957 1.00 29.76 ? 322 SER A OG 1 ATOM 2466 N N . PRO A 1 323 ? -35.633 2.077 31.242 1.00 26.63 ? 323 PRO A N 1 ATOM 2467 C CA . PRO A 1 323 ? -35.151 1.393 30.029 1.00 25.83 ? 323 PRO A CA 1 ATOM 2468 C C . PRO A 1 323 ? -34.455 2.339 29.061 1.00 25.78 ? 323 PRO A C 1 ATOM 2469 O O . PRO A 1 323 ? -33.469 1.931 28.447 1.00 27.10 ? 323 PRO A O 1 ATOM 2470 C CB . PRO A 1 323 ? -36.415 0.807 29.391 1.00 26.13 ? 323 PRO A CB 1 ATOM 2471 C CG . PRO A 1 323 ? -37.508 0.934 30.417 1.00 27.34 ? 323 PRO A CG 1 ATOM 2472 C CD . PRO A 1 323 ? -37.110 2.118 31.296 1.00 26.95 ? 323 PRO A CD 1 ATOM 2473 N N . ALA A 1 324 ? -34.911 3.592 28.954 1.00 24.89 ? 324 ALA A N 1 ATOM 2474 C CA . ALA A 1 324 ? -34.277 4.607 28.081 1.00 24.03 ? 324 ALA A CA 1 ATOM 2475 C C . ALA A 1 324 ? -32.753 4.812 28.315 1.00 23.97 ? 324 ALA A C 1 ATOM 2476 O O . ALA A 1 324 ? -31.958 4.951 27.375 1.00 24.04 ? 324 ALA A O 1 ATOM 2477 C CB . ALA A 1 324 ? -34.999 5.954 28.225 1.00 23.37 ? 324 ALA A CB 1 ATOM 2478 N N . THR A 1 325 ? -32.369 4.861 29.590 1.00 23.43 ? 325 THR A N 1 ATOM 2479 C CA . THR A 1 325 ? -31.015 5.168 29.992 1.00 22.25 ? 325 THR A CA 1 ATOM 2480 C C . THR A 1 325 ? -30.266 3.930 30.499 1.00 22.43 ? 325 THR A C 1 ATOM 2481 O O . THR A 1 325 ? -29.056 3.985 30.675 1.00 22.88 ? 325 THR A O 1 ATOM 2482 C CB . THR A 1 325 ? -31.025 6.286 31.014 1.00 22.10 ? 325 THR A CB 1 ATOM 2483 O OG1 . THR A 1 325 ? -32.147 6.105 31.891 1.00 21.34 ? 325 THR A OG1 1 ATOM 2484 C CG2 . THR A 1 325 ? -31.219 7.601 30.292 1.00 22.23 ? 325 THR A CG2 1 ATOM 2485 N N . PHE A 1 326 ? -30.978 2.821 30.732 1.00 21.26 ? 326 PHE A N 1 ATOM 2486 C CA . PHE A 1 326 ? -30.307 1.555 30.971 1.00 20.64 ? 326 PHE A CA 1 ATOM 2487 C C . PHE A 1 326 ? -31.118 0.364 30.404 1.00 20.61 ? 326 PHE A C 1 ATOM 2488 O O . PHE A 1 326 ? -31.753 -0.362 31.195 1.00 21.62 ? 326 PHE A O 1 ATOM 2489 C CB . PHE A 1 326 ? -30.033 1.366 32.482 1.00 19.90 ? 326 PHE A CB 1 ATOM 2490 C CG . PHE A 1 326 ? -29.101 0.226 32.785 1.00 20.26 ? 326 PHE A CG 1 ATOM 2491 C CD1 . PHE A 1 326 ? -27.708 0.383 32.652 1.00 19.65 ? 326 PHE A CD1 1 ATOM 2492 C CD2 . PHE A 1 326 ? -29.604 -1.033 33.140 1.00 19.56 ? 326 PHE A CD2 1 ATOM 2493 C CE1 . PHE A 1 326 ? -26.841 -0.705 32.913 1.00 18.38 ? 326 PHE A CE1 1 ATOM 2494 C CE2 . PHE A 1 326 ? -28.748 -2.119 33.390 1.00 19.54 ? 326 PHE A CE2 1 ATOM 2495 C CZ . PHE A 1 326 ? -27.365 -1.945 33.272 1.00 19.67 ? 326 PHE A CZ 1 ATOM 2496 N N . PRO A 1 327 ? -31.105 0.145 29.063 1.00 19.76 ? 327 PRO A N 1 ATOM 2497 C CA . PRO A 1 327 ? -31.956 -0.918 28.526 1.00 19.91 ? 327 PRO A CA 1 ATOM 2498 C C . PRO A 1 327 ? -31.350 -2.305 28.766 1.00 19.59 ? 327 PRO A C 1 ATOM 2499 O O . PRO A 1 327 ? -30.147 -2.472 28.638 1.00 19.29 ? 327 PRO A O 1 ATOM 2500 C CB . PRO A 1 327 ? -32.031 -0.576 27.006 1.00 19.76 ? 327 PRO A CB 1 ATOM 2501 C CG . PRO A 1 327 ? -30.754 0.115 26.746 1.00 19.37 ? 327 PRO A CG 1 ATOM 2502 C CD . PRO A 1 327 ? -30.361 0.836 27.987 1.00 19.44 ? 327 PRO A CD 1 ATOM 2503 N N . LEU A 1 328 ? -32.188 -3.292 29.071 1.00 19.87 ? 328 LEU A N 1 ATOM 2504 C CA . LEU A 1 328 ? -31.698 -4.644 29.493 1.00 20.75 ? 328 LEU A CA 1 ATOM 2505 C C . LEU A 1 328 ? -31.596 -5.703 28.391 1.00 20.95 ? 328 LEU A C 1 ATOM 2506 O O . LEU A 1 328 ? -31.127 -6.831 28.637 1.00 21.12 ? 328 LEU A O 1 ATOM 2507 C CB . LEU A 1 328 ? -32.601 -5.212 30.611 1.00 19.93 ? 328 LEU A CB 1 ATOM 2508 C CG . LEU A 1 328 ? -32.796 -4.291 31.827 1.00 22.41 ? 328 LEU A CG 1 ATOM 2509 C CD1 . LEU A 1 328 ? -33.909 -4.773 32.769 1.00 20.26 ? 328 LEU A CD1 1 ATOM 2510 C CD2 . LEU A 1 328 ? -31.463 -4.184 32.562 1.00 21.30 ? 328 LEU A CD2 1 ATOM 2511 N N . ASN A 1 329 ? -32.100 -5.389 27.206 1.00 21.78 ? 329 ASN A N 1 ATOM 2512 C CA . ASN A 1 329 ? -32.197 -6.408 26.160 1.00 23.22 ? 329 ASN A CA 1 ATOM 2513 C C . ASN A 1 329 ? -31.622 -5.882 24.887 1.00 22.45 ? 329 ASN A C 1 ATOM 2514 O O . ASN A 1 329 ? -32.082 -6.265 23.809 1.00 22.98 ? 329 ASN A O 1 ATOM 2515 C CB . ASN A 1 329 ? -33.654 -6.802 25.862 1.00 23.98 ? 329 ASN A CB 1 ATOM 2516 C CG . ASN A 1 329 ? -34.340 -7.481 27.025 1.00 28.19 ? 329 ASN A CG 1 ATOM 2517 O OD1 . ASN A 1 329 ? -33.930 -8.558 27.463 1.00 33.59 ? 329 ASN A OD1 1 ATOM 2518 N ND2 . ASN A 1 329 ? -35.414 -6.873 27.514 1.00 30.88 ? 329 ASN A ND2 1 ATOM 2519 N N . SER A 1 330 ? -30.660 -4.975 24.982 1.00 21.77 ? 330 SER A N 1 ATOM 2520 C CA . SER A 1 330 ? -29.944 -4.614 23.793 1.00 21.60 ? 330 SER A CA 1 ATOM 2521 C C . SER A 1 330 ? -29.092 -5.858 23.697 1.00 22.00 ? 330 SER A C 1 ATOM 2522 O O . SER A 1 330 ? -29.207 -6.811 24.545 1.00 23.34 ? 330 SER A O 1 ATOM 2523 C CB . SER A 1 330 ? -29.108 -3.380 24.009 1.00 21.47 ? 330 SER A CB 1 ATOM 2524 O OG . SER A 1 330 ? -29.904 -2.400 24.611 1.00 20.71 ? 330 SER A OG 1 ATOM 2525 N N . THR A 1 331 ? -28.275 -5.921 22.685 1.00 20.45 ? 331 THR A N 1 ATOM 2526 C CA . THR A 1 331 ? -27.492 -7.137 22.539 1.00 19.80 ? 331 THR A CA 1 ATOM 2527 C C . THR A 1 331 ? -26.020 -6.755 22.546 1.00 19.07 ? 331 THR A C 1 ATOM 2528 O O . THR A 1 331 ? -25.150 -7.578 22.874 1.00 19.11 ? 331 THR A O 1 ATOM 2529 C CB . THR A 1 331 ? -27.896 -7.831 21.216 1.00 20.04 ? 331 THR A CB 1 ATOM 2530 O OG1 . THR A 1 331 ? -29.075 -8.586 21.464 1.00 19.19 ? 331 THR A OG1 1 ATOM 2531 C CG2 . THR A 1 331 ? -26.780 -8.711 20.614 1.00 18.96 ? 331 THR A CG2 1 ATOM 2532 N N . LEU A 1 332 ? -25.782 -5.489 22.203 1.00 16.98 ? 332 LEU A N 1 ATOM 2533 C CA . LEU A 1 332 ? -24.460 -4.922 22.144 1.00 16.68 ? 332 LEU A CA 1 ATOM 2534 C C . LEU A 1 332 ? -24.441 -3.649 22.965 1.00 15.70 ? 332 LEU A C 1 ATOM 2535 O O . LEU A 1 332 ? -25.429 -2.922 23.012 1.00 16.66 ? 332 LEU A O 1 ATOM 2536 C CB . LEU A 1 332 ? -24.074 -4.592 20.699 1.00 16.43 ? 332 LEU A CB 1 ATOM 2537 C CG . LEU A 1 332 ? -24.213 -5.702 19.664 1.00 14.55 ? 332 LEU A CG 1 ATOM 2538 C CD1 . LEU A 1 332 ? -24.375 -5.065 18.334 1.00 14.09 ? 332 LEU A CD1 1 ATOM 2539 C CD2 . LEU A 1 332 ? -22.957 -6.560 19.681 1.00 13.64 ? 332 LEU A CD2 1 ATOM 2540 N N . TYR A 1 333 ? -23.303 -3.376 23.569 1.00 14.54 ? 333 TYR A N 1 ATOM 2541 C CA . TYR A 1 333 ? -23.150 -2.330 24.568 1.00 13.33 ? 333 TYR A CA 1 ATOM 2542 C C . TYR A 1 333 ? -21.690 -1.902 24.462 1.00 14.28 ? 333 TYR A C 1 ATOM 2543 O O . TYR A 1 333 ? -20.767 -2.725 24.237 1.00 13.19 ? 333 TYR A O 1 ATOM 2544 C CB . TYR A 1 333 ? -23.413 -2.858 25.975 1.00 12.88 ? 333 TYR A CB 1 ATOM 2545 C CG . TYR A 1 333 ? -24.870 -3.203 26.337 1.00 12.30 ? 333 TYR A CG 1 ATOM 2546 C CD1 . TYR A 1 333 ? -25.735 -2.245 26.837 1.00 11.03 ? 333 TYR A CD1 1 ATOM 2547 C CD2 . TYR A 1 333 ? -25.344 -4.515 26.207 1.00 10.72 ? 333 TYR A CD2 1 ATOM 2548 C CE1 . TYR A 1 333 ? -27.088 -2.604 27.204 1.00 11.18 ? 333 TYR A CE1 1 ATOM 2549 C CE2 . TYR A 1 333 ? -26.607 -4.873 26.551 1.00 10.40 ? 333 TYR A CE2 1 ATOM 2550 C CZ . TYR A 1 333 ? -27.504 -3.919 27.043 1.00 12.97 ? 333 TYR A CZ 1 ATOM 2551 O OH . TYR A 1 333 ? -28.811 -4.304 27.366 1.00 12.31 ? 333 TYR A OH 1 ATOM 2552 N N . ALA A 1 334 ? -21.487 -0.605 24.588 1.00 14.18 ? 334 ALA A N 1 ATOM 2553 C CA . ALA A 1 334 ? -20.181 -0.049 24.519 1.00 14.36 ? 334 ALA A CA 1 ATOM 2554 C C . ALA A 1 334 ? -20.079 1.037 25.611 1.00 15.53 ? 334 ALA A C 1 ATOM 2555 O O . ALA A 1 334 ? -20.977 1.941 25.736 1.00 15.24 ? 334 ALA A O 1 ATOM 2556 C CB . ALA A 1 334 ? -19.942 0.503 23.138 1.00 13.85 ? 334 ALA A CB 1 ATOM 2557 N N . ASP A 1 335 ? -19.034 0.896 26.454 1.00 15.97 ? 335 ASP A N 1 ATOM 2558 C CA . ASP A 1 335 ? -18.750 1.859 27.530 1.00 15.72 ? 335 ASP A CA 1 ATOM 2559 C C . ASP A 1 335 ? -17.316 2.409 27.375 1.00 16.07 ? 335 ASP A C 1 ATOM 2560 O O . ASP A 1 335 ? -16.388 1.720 26.904 1.00 16.95 ? 335 ASP A O 1 ATOM 2561 C CB . ASP A 1 335 ? -18.963 1.259 28.914 1.00 15.62 ? 335 ASP A CB 1 ATOM 2562 C CG . ASP A 1 335 ? -20.417 0.912 29.226 1.00 17.31 ? 335 ASP A CG 1 ATOM 2563 O OD1 . ASP A 1 335 ? -21.314 1.822 29.191 1.00 15.87 ? 335 ASP A OD1 1 ATOM 2564 O OD2 . ASP A 1 335 ? -20.643 -0.289 29.592 1.00 17.11 ? 335 ASP A OD2 1 ATOM 2565 N N . PHE A 1 336 ? -17.135 3.660 27.769 1.00 16.13 ? 336 PHE A N 1 ATOM 2566 C CA . PHE A 1 336 ? -15.875 4.372 27.583 1.00 16.09 ? 336 PHE A CA 1 ATOM 2567 C C . PHE A 1 336 ? -15.515 5.072 28.870 1.00 16.62 ? 336 PHE A C 1 ATOM 2568 O O . PHE A 1 336 ? -16.355 5.805 29.448 1.00 17.75 ? 336 PHE A O 1 ATOM 2569 C CB . PHE A 1 336 ? -16.006 5.393 26.423 1.00 16.54 ? 336 PHE A CB 1 ATOM 2570 C CG . PHE A 1 336 ? -16.174 4.744 25.091 1.00 14.66 ? 336 PHE A CG 1 ATOM 2571 C CD1 . PHE A 1 336 ? -17.424 4.348 24.664 1.00 11.96 ? 336 PHE A CD1 1 ATOM 2572 C CD2 . PHE A 1 336 ? -15.064 4.464 24.303 1.00 14.49 ? 336 PHE A CD2 1 ATOM 2573 C CE1 . PHE A 1 336 ? -17.578 3.711 23.453 1.00 13.09 ? 336 PHE A CE1 1 ATOM 2574 C CE2 . PHE A 1 336 ? -15.190 3.805 23.099 1.00 12.54 ? 336 PHE A CE2 1 ATOM 2575 C CZ . PHE A 1 336 ? -16.461 3.417 22.683 1.00 15.47 ? 336 PHE A CZ 1 ATOM 2576 N N . SER A 1 337 ? -14.278 4.876 29.323 1.00 16.25 ? 337 SER A N 1 ATOM 2577 C CA . SER A 1 337 ? -13.896 5.315 30.665 1.00 15.82 ? 337 SER A CA 1 ATOM 2578 C C . SER A 1 337 ? -12.379 5.563 30.778 1.00 16.12 ? 337 SER A C 1 ATOM 2579 O O . SER A 1 337 ? -11.699 5.666 29.739 1.00 17.64 ? 337 SER A O 1 ATOM 2580 C CB . SER A 1 337 ? -14.364 4.302 31.695 1.00 15.24 ? 337 SER A CB 1 ATOM 2581 O OG . SER A 1 337 ? -14.489 4.886 32.971 1.00 17.26 ? 337 SER A OG 1 ATOM 2582 N N . HIS A 1 338 ? -11.863 5.697 32.016 1.00 15.70 ? 338 HIS A N 1 ATOM 2583 C CA . HIS A 1 338 ? -10.417 5.836 32.252 1.00 14.48 ? 338 HIS A CA 1 ATOM 2584 C C . HIS A 1 338 ? -9.818 4.534 32.711 1.00 14.68 ? 338 HIS A C 1 ATOM 2585 O O . HIS A 1 338 ? -10.531 3.638 33.190 1.00 14.76 ? 338 HIS A O 1 ATOM 2586 C CB . HIS A 1 338 ? -10.111 6.879 33.323 1.00 14.38 ? 338 HIS A CB 1 ATOM 2587 C CG . HIS A 1 338 ? -10.786 8.195 33.112 1.00 12.84 ? 338 HIS A CG 1 ATOM 2588 N ND1 . HIS A 1 338 ? -10.147 9.267 32.533 1.00 10.91 ? 338 HIS A ND1 1 ATOM 2589 C CD2 . HIS A 1 338 ? -12.041 8.617 33.418 1.00 14.17 ? 338 HIS A CD2 1 ATOM 2590 C CE1 . HIS A 1 338 ? -10.983 10.290 32.470 1.00 14.57 ? 338 HIS A CE1 1 ATOM 2591 N NE2 . HIS A 1 338 ? -12.137 9.923 33.005 1.00 16.11 ? 338 HIS A NE2 1 ATOM 2592 N N . ASP A 1 339 ? -8.500 4.479 32.616 1.00 15.08 ? 339 ASP A N 1 ATOM 2593 C CA . ASP A 1 339 ? -7.675 3.405 33.139 1.00 15.98 ? 339 ASP A CA 1 ATOM 2594 C C . ASP A 1 339 ? -8.011 3.025 34.592 1.00 16.01 ? 339 ASP A C 1 ATOM 2595 O O . ASP A 1 339 ? -8.173 1.849 34.899 1.00 16.87 ? 339 ASP A O 1 ATOM 2596 C CB . ASP A 1 339 ? -6.154 3.736 32.955 1.00 15.18 ? 339 ASP A CB 1 ATOM 2597 C CG . ASP A 1 339 ? -5.686 4.946 33.770 1.00 16.05 ? 339 ASP A CG 1 ATOM 2598 O OD1 . ASP A 1 339 ? -6.461 5.494 34.585 1.00 15.14 ? 339 ASP A OD1 1 ATOM 2599 O OD2 . ASP A 1 339 ? -4.518 5.367 33.611 1.00 17.05 ? 339 ASP A OD2 1 ATOM 2600 N N . ASN A 1 340 ? -8.144 4.017 35.465 1.00 15.95 ? 340 ASN A N 1 ATOM 2601 C CA . ASN A 1 340 ? -8.281 3.735 36.880 1.00 16.80 ? 340 ASN A CA 1 ATOM 2602 C C . ASN A 1 340 ? -9.556 2.995 37.169 1.00 17.14 ? 340 ASN A C 1 ATOM 2603 O O . ASN A 1 340 ? -9.525 2.004 37.905 1.00 17.25 ? 340 ASN A O 1 ATOM 2604 C CB . ASN A 1 340 ? -8.176 4.999 37.745 1.00 16.30 ? 340 ASN A CB 1 ATOM 2605 C CG . ASN A 1 340 ? -6.759 5.576 37.775 1.00 17.47 ? 340 ASN A CG 1 ATOM 2606 O OD1 . ASN A 1 340 ? -5.742 4.868 37.495 1.00 14.91 ? 340 ASN A OD1 1 ATOM 2607 N ND2 . ASN A 1 340 ? -6.678 6.874 38.073 1.00 15.09 ? 340 ASN A ND2 1 ATOM 2608 N N . GLY A 1 341 ? -10.676 3.457 36.612 1.00 16.13 ? 341 GLY A N 1 ATOM 2609 C CA . GLY A 1 341 ? -11.916 2.767 36.854 1.00 16.30 ? 341 GLY A CA 1 ATOM 2610 C C . GLY A 1 341 ? -11.928 1.386 36.193 1.00 16.76 ? 341 GLY A C 1 ATOM 2611 O O . GLY A 1 341 ? -12.716 0.510 36.573 1.00 16.61 ? 341 GLY A O 1 ATOM 2612 N N . ILE A 1 342 ? -11.088 1.196 35.171 1.00 16.71 ? 342 ILE A N 1 ATOM 2613 C CA . ILE A 1 342 ? -11.154 -0.028 34.382 1.00 16.45 ? 342 ILE A CA 1 ATOM 2614 C C . ILE A 1 342 ? -10.411 -1.084 35.185 1.00 17.28 ? 342 ILE A C 1 ATOM 2615 O O . ILE A 1 342 ? -10.782 -2.249 35.180 1.00 18.07 ? 342 ILE A O 1 ATOM 2616 C CB . ILE A 1 342 ? -10.526 0.154 32.945 1.00 16.72 ? 342 ILE A CB 1 ATOM 2617 C CG1 . ILE A 1 342 ? -11.479 0.901 32.031 1.00 15.60 ? 342 ILE A CG1 1 ATOM 2618 C CG2 . ILE A 1 342 ? -10.308 -1.156 32.289 1.00 14.46 ? 342 ILE A CG2 1 ATOM 2619 C CD1 . ILE A 1 342 ? -10.823 1.436 30.788 1.00 17.19 ? 342 ILE A CD1 1 ATOM 2620 N N . ILE A 1 343 ? -9.334 -0.670 35.866 1.00 17.56 ? 343 ILE A N 1 ATOM 2621 C CA . ILE A 1 343 ? -8.595 -1.551 36.750 1.00 15.98 ? 343 ILE A CA 1 ATOM 2622 C C . ILE A 1 343 ? -9.595 -2.038 37.794 1.00 15.03 ? 343 ILE A C 1 ATOM 2623 O O . ILE A 1 343 ? -9.836 -3.224 37.923 1.00 15.42 ? 343 ILE A O 1 ATOM 2624 C CB . ILE A 1 343 ? -7.360 -0.844 37.400 1.00 16.03 ? 343 ILE A CB 1 ATOM 2625 C CG1 . ILE A 1 343 ? -6.300 -0.428 36.354 1.00 14.18 ? 343 ILE A CG1 1 ATOM 2626 C CG2 . ILE A 1 343 ? -6.753 -1.736 38.460 1.00 15.99 ? 343 ILE A CG2 1 ATOM 2627 C CD1 . ILE A 1 343 ? -5.411 -1.537 35.840 1.00 7.42 ? 343 ILE A CD1 1 ATOM 2628 N N . SER A 1 344 ? -10.217 -1.130 38.519 1.00 14.81 ? 344 SER A N 1 ATOM 2629 C CA . SER A 1 344 ? -11.174 -1.541 39.572 1.00 14.81 ? 344 SER A CA 1 ATOM 2630 C C . SER A 1 344 ? -12.227 -2.508 39.054 1.00 15.17 ? 344 SER A C 1 ATOM 2631 O O . SER A 1 344 ? -12.584 -3.493 39.722 1.00 15.80 ? 344 SER A O 1 ATOM 2632 C CB . SER A 1 344 ? -11.844 -0.356 40.241 1.00 14.04 ? 344 SER A CB 1 ATOM 2633 O OG . SER A 1 344 ? -10.886 0.518 40.772 1.00 15.41 ? 344 SER A OG 1 ATOM 2634 N N . ILE A 1 345 ? -12.692 -2.258 37.842 1.00 14.89 ? 345 ILE A N 1 ATOM 2635 C CA . ILE A 1 345 ? -13.702 -3.121 37.248 1.00 15.26 ? 345 ILE A CA 1 ATOM 2636 C C . ILE A 1 345 ? -13.219 -4.562 36.932 1.00 14.63 ? 345 ILE A C 1 ATOM 2637 O O . ILE A 1 345 ? -13.926 -5.524 37.204 1.00 13.11 ? 345 ILE A O 1 ATOM 2638 C CB . ILE A 1 345 ? -14.342 -2.442 36.005 1.00 15.11 ? 345 ILE A CB 1 ATOM 2639 C CG1 . ILE A 1 345 ? -15.117 -1.199 36.423 1.00 14.16 ? 345 ILE A CG1 1 ATOM 2640 C CG2 . ILE A 1 345 ? -15.243 -3.426 35.279 1.00 13.80 ? 345 ILE A CG2 1 ATOM 2641 C CD1 . ILE A 1 345 ? -15.568 -0.345 35.235 1.00 14.92 ? 345 ILE A CD1 1 ATOM 2642 N N . LEU A 1 346 ? -12.033 -4.668 36.314 1.00 14.92 ? 346 LEU A N 1 ATOM 2643 C CA . LEU A 1 346 ? -11.410 -5.927 35.994 1.00 15.08 ? 346 LEU A CA 1 ATOM 2644 C C . LEU A 1 346 ? -11.288 -6.824 37.273 1.00 16.29 ? 346 LEU A C 1 ATOM 2645 O O . LEU A 1 346 ? -11.638 -8.034 37.241 1.00 16.23 ? 346 LEU A O 1 ATOM 2646 C CB . LEU A 1 346 ? -10.030 -5.685 35.367 1.00 15.43 ? 346 LEU A CB 1 ATOM 2647 C CG . LEU A 1 346 ? -9.913 -5.017 33.994 1.00 16.23 ? 346 LEU A CG 1 ATOM 2648 C CD1 . LEU A 1 346 ? -8.464 -4.969 33.441 1.00 17.22 ? 346 LEU A CD1 1 ATOM 2649 C CD2 . LEU A 1 346 ? -10.870 -5.644 32.976 1.00 15.93 ? 346 LEU A CD2 1 ATOM 2650 N N . PHE A 1 347 ? -10.801 -6.221 38.372 1.00 15.68 ? 347 PHE A N 1 ATOM 2651 C CA . PHE A 1 347 ? -10.632 -6.909 39.644 1.00 16.05 ? 347 PHE A CA 1 ATOM 2652 C C . PHE A 1 347 ? -11.945 -7.279 40.322 1.00 16.31 ? 347 PHE A C 1 ATOM 2653 O O . PHE A 1 347 ? -12.074 -8.410 40.789 1.00 16.97 ? 347 PHE A O 1 ATOM 2654 C CB . PHE A 1 347 ? -9.694 -6.160 40.595 1.00 15.24 ? 347 PHE A CB 1 ATOM 2655 C CG . PHE A 1 347 ? -8.206 -6.357 40.266 1.00 14.53 ? 347 PHE A CG 1 ATOM 2656 C CD1 . PHE A 1 347 ? -7.491 -7.451 40.778 1.00 11.81 ? 347 PHE A CD1 1 ATOM 2657 C CD2 . PHE A 1 347 ? -7.516 -5.436 39.470 1.00 10.27 ? 347 PHE A CD2 1 ATOM 2658 C CE1 . PHE A 1 347 ? -6.101 -7.608 40.484 1.00 12.20 ? 347 PHE A CE1 1 ATOM 2659 C CE2 . PHE A 1 347 ? -6.103 -5.594 39.171 1.00 10.95 ? 347 PHE A CE2 1 ATOM 2660 C CZ . PHE A 1 347 ? -5.413 -6.659 39.671 1.00 10.09 ? 347 PHE A CZ 1 ATOM 2661 N N . ALA A 1 348 ? -12.926 -6.375 40.323 1.00 16.24 ? 348 ALA A N 1 ATOM 2662 C CA . ALA A 1 348 ? -14.261 -6.695 40.860 1.00 16.20 ? 348 ALA A CA 1 ATOM 2663 C C . ALA A 1 348 ? -14.938 -7.815 40.080 1.00 16.62 ? 348 ALA A C 1 ATOM 2664 O O . ALA A 1 348 ? -15.847 -8.477 40.588 1.00 15.75 ? 348 ALA A O 1 ATOM 2665 C CB . ALA A 1 348 ? -15.141 -5.495 40.879 1.00 16.25 ? 348 ALA A CB 1 ATOM 2666 N N . LEU A 1 349 ? -14.469 -8.048 38.846 1.00 16.50 ? 349 LEU A N 1 ATOM 2667 C CA . LEU A 1 349 ? -15.067 -9.105 38.021 1.00 16.37 ? 349 LEU A CA 1 ATOM 2668 C C . LEU A 1 349 ? -14.390 -10.444 38.277 1.00 16.73 ? 349 LEU A C 1 ATOM 2669 O O . LEU A 1 349 ? -14.758 -11.450 37.688 1.00 17.55 ? 349 LEU A O 1 ATOM 2670 C CB . LEU A 1 349 ? -15.053 -8.737 36.524 1.00 15.50 ? 349 LEU A CB 1 ATOM 2671 C CG . LEU A 1 349 ? -16.057 -7.634 36.160 1.00 16.53 ? 349 LEU A CG 1 ATOM 2672 C CD1 . LEU A 1 349 ? -15.873 -7.117 34.754 1.00 14.37 ? 349 LEU A CD1 1 ATOM 2673 C CD2 . LEU A 1 349 ? -17.453 -8.144 36.387 1.00 16.21 ? 349 LEU A CD2 1 ATOM 2674 N N . GLY A 1 350 ? -13.389 -10.449 39.147 1.00 17.09 ? 350 GLY A N 1 ATOM 2675 C CA . GLY A 1 350 ? -12.640 -11.660 39.451 1.00 17.21 ? 350 GLY A CA 1 ATOM 2676 C C . GLY A 1 350 ? -11.516 -11.965 38.481 1.00 18.19 ? 350 GLY A C 1 ATOM 2677 O O . GLY A 1 350 ? -10.781 -12.922 38.698 1.00 18.72 ? 350 GLY A O 1 ATOM 2678 N N . LEU A 1 351 ? -11.346 -11.162 37.429 1.00 18.45 ? 351 LEU A N 1 ATOM 2679 C CA . LEU A 1 351 ? -10.468 -11.573 36.309 1.00 19.25 ? 351 LEU A CA 1 ATOM 2680 C C . LEU A 1 351 ? -9.022 -11.782 36.694 1.00 19.31 ? 351 LEU A C 1 ATOM 2681 O O . LEU A 1 351 ? -8.238 -12.372 35.913 1.00 20.67 ? 351 LEU A O 1 ATOM 2682 C CB . LEU A 1 351 ? -10.542 -10.608 35.109 1.00 19.09 ? 351 LEU A CB 1 ATOM 2683 C CG . LEU A 1 351 ? -11.977 -10.232 34.712 1.00 21.30 ? 351 LEU A CG 1 ATOM 2684 C CD1 . LEU A 1 351 ? -11.972 -9.226 33.559 1.00 20.31 ? 351 LEU A CD1 1 ATOM 2685 C CD2 . LEU A 1 351 ? -12.809 -11.492 34.370 1.00 20.94 ? 351 LEU A CD2 1 ATOM 2686 N N . TYR A 1 352 ? -8.648 -11.288 37.869 1.00 19.19 ? 352 TYR A N 1 ATOM 2687 C CA . TYR A 1 352 ? -7.241 -11.414 38.287 1.00 19.18 ? 352 TYR A CA 1 ATOM 2688 C C . TYR A 1 352 ? -7.074 -12.115 39.631 1.00 19.63 ? 352 TYR A C 1 ATOM 2689 O O . TYR A 1 352 ? -6.146 -11.848 40.391 1.00 19.34 ? 352 TYR A O 1 ATOM 2690 C CB . TYR A 1 352 ? -6.451 -10.094 38.124 1.00 17.88 ? 352 TYR A CB 1 ATOM 2691 C CG . TYR A 1 352 ? -6.312 -9.765 36.667 1.00 17.05 ? 352 TYR A CG 1 ATOM 2692 C CD1 . TYR A 1 352 ? -5.341 -10.392 35.865 1.00 15.12 ? 352 TYR A CD1 1 ATOM 2693 C CD2 . TYR A 1 352 ? -7.190 -8.861 36.055 1.00 13.23 ? 352 TYR A CD2 1 ATOM 2694 C CE1 . TYR A 1 352 ? -5.242 -10.102 34.481 1.00 13.07 ? 352 TYR A CE1 1 ATOM 2695 C CE2 . TYR A 1 352 ? -7.085 -8.566 34.688 1.00 13.87 ? 352 TYR A CE2 1 ATOM 2696 C CZ . TYR A 1 352 ? -6.132 -9.200 33.905 1.00 14.73 ? 352 TYR A CZ 1 ATOM 2697 O OH . TYR A 1 352 ? -6.082 -8.868 32.551 1.00 16.41 ? 352 TYR A OH 1 ATOM 2698 N N . ASN A 1 353 ? -7.969 -13.064 39.865 1.00 20.22 ? 353 ASN A N 1 ATOM 2699 C CA . ASN A 1 353 ? -8.008 -13.778 41.114 1.00 21.44 ? 353 ASN A CA 1 ATOM 2700 C C . ASN A 1 353 ? -7.097 -15.003 41.175 1.00 22.28 ? 353 ASN A C 1 ATOM 2701 O O . ASN A 1 353 ? -7.245 -15.844 42.060 1.00 22.72 ? 353 ASN A O 1 ATOM 2702 C CB . ASN A 1 353 ? -9.447 -14.142 41.426 1.00 21.48 ? 353 ASN A CB 1 ATOM 2703 C CG . ASN A 1 353 ? -10.096 -13.161 42.297 1.00 21.15 ? 353 ASN A CG 1 ATOM 2704 O OD1 . ASN A 1 353 ? -9.696 -11.996 42.376 1.00 20.33 ? 353 ASN A OD1 1 ATOM 2705 N ND2 . ASN A 1 353 ? -11.118 -13.616 42.970 1.00 21.07 ? 353 ASN A ND2 1 ATOM 2706 N N . GLY A 1 354 ? -6.156 -15.102 40.245 1.00 23.16 ? 354 GLY A N 1 ATOM 2707 C CA . GLY A 1 354 ? -5.108 -16.104 40.340 1.00 24.25 ? 354 GLY A CA 1 ATOM 2708 C C . GLY A 1 354 ? -3.778 -15.389 40.436 1.00 25.48 ? 354 GLY A C 1 ATOM 2709 O O . GLY A 1 354 ? -2.728 -16.034 40.436 1.00 26.11 ? 354 GLY A O 1 ATOM 2710 N N . THR A 1 355 ? -3.835 -14.049 40.504 1.00 25.78 ? 355 THR A N 1 ATOM 2711 C CA . THR A 1 355 ? -2.668 -13.154 40.595 1.00 25.68 ? 355 THR A CA 1 ATOM 2712 C C . THR A 1 355 ? -2.297 -12.881 42.083 1.00 26.77 ? 355 THR A C 1 ATOM 2713 O O . THR A 1 355 ? -3.160 -12.497 42.902 1.00 26.45 ? 355 THR A O 1 ATOM 2714 C CB . THR A 1 355 ? -2.947 -11.789 39.864 1.00 25.72 ? 355 THR A CB 1 ATOM 2715 O OG1 . THR A 1 355 ? -3.068 -11.971 38.440 1.00 23.77 ? 355 THR A OG1 1 ATOM 2716 C CG2 . THR A 1 355 ? -1.855 -10.726 40.181 1.00 24.18 ? 355 THR A CG2 1 ATOM 2717 N N . LYS A 1 356 ? -1.020 -13.076 42.425 1.00 26.92 ? 356 LYS A N 1 ATOM 2718 C CA . LYS A 1 356 ? -0.534 -12.850 43.799 1.00 27.35 ? 356 LYS A CA 1 ATOM 2719 C C . LYS A 1 356 ? -0.070 -11.407 43.965 1.00 26.76 ? 356 LYS A C 1 ATOM 2720 O O . LYS A 1 356 ? 0.624 -10.892 43.097 1.00 28.40 ? 356 LYS A O 1 ATOM 2721 C CB . LYS A 1 356 ? 0.586 -13.839 44.145 1.00 27.29 ? 356 LYS A CB 1 ATOM 2722 C CG . LYS A 1 356 ? 0.083 -14.993 44.970 1.00 30.77 ? 356 LYS A CG 1 ATOM 2723 C CD . LYS A 1 356 ? 0.523 -16.381 44.464 1.00 36.04 ? 356 LYS A CD 1 ATOM 2724 C CE . LYS A 1 356 ? -0.369 -17.434 45.160 1.00 42.19 ? 356 LYS A CE 1 ATOM 2725 N NZ . LYS A 1 356 ? -0.003 -18.900 44.981 1.00 44.97 ? 356 LYS A NZ 1 ATOM 2726 N N . PRO A 1 357 ? -0.419 -10.761 45.081 1.00 26.13 ? 357 PRO A N 1 ATOM 2727 C CA . PRO A 1 357 ? -0.091 -9.353 45.294 1.00 26.14 ? 357 PRO A CA 1 ATOM 2728 C C . PRO A 1 357 ? 1.323 -9.073 44.816 1.00 25.96 ? 357 PRO A C 1 ATOM 2729 O O . PRO A 1 357 ? 2.237 -9.853 45.111 1.00 26.46 ? 357 PRO A O 1 ATOM 2730 C CB . PRO A 1 357 ? -0.180 -9.195 46.821 1.00 26.39 ? 357 PRO A CB 1 ATOM 2731 C CG . PRO A 1 357 ? -1.118 -10.245 47.251 1.00 26.78 ? 357 PRO A CG 1 ATOM 2732 C CD . PRO A 1 357 ? -0.974 -11.398 46.285 1.00 26.18 ? 357 PRO A CD 1 ATOM 2733 N N . LEU A 1 358 ? 1.515 -8.010 44.058 1.00 25.34 ? 358 LEU A N 1 ATOM 2734 C CA . LEU A 1 358 ? 2.805 -7.818 43.462 1.00 25.74 ? 358 LEU A CA 1 ATOM 2735 C C . LEU A 1 358 ? 3.796 -7.376 44.528 1.00 27.38 ? 358 LEU A C 1 ATOM 2736 O O . LEU A 1 358 ? 3.451 -6.549 45.406 1.00 27.31 ? 358 LEU A O 1 ATOM 2737 C CB . LEU A 1 358 ? 2.762 -6.786 42.334 1.00 24.54 ? 358 LEU A CB 1 ATOM 2738 C CG . LEU A 1 358 ? 1.633 -6.789 41.306 1.00 24.85 ? 358 LEU A CG 1 ATOM 2739 C CD1 . LEU A 1 358 ? 2.009 -5.833 40.195 1.00 22.11 ? 358 LEU A CD1 1 ATOM 2740 C CD2 . LEU A 1 358 ? 1.258 -8.168 40.743 1.00 20.57 ? 358 LEU A CD2 1 ATOM 2741 N N . SER A 1 359 ? 5.016 -7.927 44.427 1.00 28.62 ? 359 SER A N 1 ATOM 2742 C CA . SER A 1 359 ? 6.158 -7.568 45.266 1.00 29.52 ? 359 SER A CA 1 ATOM 2743 C C . SER A 1 359 ? 6.394 -6.072 45.167 1.00 29.92 ? 359 SER A C 1 ATOM 2744 O O . SER A 1 359 ? 6.416 -5.516 44.071 1.00 30.37 ? 359 SER A O 1 ATOM 2745 C CB . SER A 1 359 ? 7.432 -8.342 44.823 1.00 29.93 ? 359 SER A CB 1 ATOM 2746 O OG . SER A 1 359 ? 8.640 -7.699 45.250 1.00 29.76 ? 359 SER A OG 1 ATOM 2747 N N . THR A 1 360 ? 6.560 -5.427 46.312 1.00 30.48 ? 360 THR A N 1 ATOM 2748 C CA . THR A 1 360 ? 6.901 -3.999 46.350 1.00 31.48 ? 360 THR A CA 1 ATOM 2749 C C . THR A 1 360 ? 8.406 -3.703 46.084 1.00 31.90 ? 360 THR A C 1 ATOM 2750 O O . THR A 1 360 ? 8.789 -2.548 45.934 1.00 31.43 ? 360 THR A O 1 ATOM 2751 C CB . THR A 1 360 ? 6.419 -3.354 47.688 1.00 31.47 ? 360 THR A CB 1 ATOM 2752 O OG1 . THR A 1 360 ? 7.029 -4.035 48.779 1.00 30.18 ? 360 THR A OG1 1 ATOM 2753 C CG2 . THR A 1 360 ? 4.891 -3.501 47.848 1.00 31.17 ? 360 THR A CG2 1 ATOM 2754 N N . THR A 1 361 ? 9.230 -4.745 45.969 1.00 33.32 ? 361 THR A N 1 ATOM 2755 C CA . THR A 1 361 ? 10.702 -4.602 46.017 1.00 34.58 ? 361 THR A CA 1 ATOM 2756 C C . THR A 1 361 ? 11.436 -5.154 44.788 1.00 35.27 ? 361 THR A C 1 ATOM 2757 O O . THR A 1 361 ? 12.498 -4.657 44.410 1.00 35.04 ? 361 THR A O 1 ATOM 2758 C CB . THR A 1 361 ? 11.283 -5.370 47.232 1.00 34.80 ? 361 THR A CB 1 ATOM 2759 O OG1 . THR A 1 361 ? 11.145 -6.776 46.992 1.00 34.31 ? 361 THR A OG1 1 ATOM 2760 C CG2 . THR A 1 361 ? 10.557 -4.995 48.548 1.00 34.52 ? 361 THR A CG2 1 ATOM 2761 N N . THR A 1 362 ? 10.881 -6.217 44.194 1.00 36.74 ? 362 THR A N 1 ATOM 2762 C CA . THR A 1 362 ? 11.429 -6.833 42.961 1.00 37.11 ? 362 THR A CA 1 ATOM 2763 C C . THR A 1 362 ? 10.425 -6.852 41.790 1.00 36.70 ? 362 THR A C 1 ATOM 2764 O O . THR A 1 362 ? 9.223 -7.000 42.006 1.00 36.79 ? 362 THR A O 1 ATOM 2765 C CB . THR A 1 362 ? 11.832 -8.312 43.208 1.00 37.92 ? 362 THR A CB 1 ATOM 2766 O OG1 . THR A 1 362 ? 11.624 -8.662 44.593 1.00 39.39 ? 362 THR A OG1 1 ATOM 2767 C CG2 . THR A 1 362 ? 13.295 -8.551 42.768 1.00 38.34 ? 362 THR A CG2 1 ATOM 2768 N N . VAL A 1 363 ? 10.938 -6.697 40.565 1.00 36.25 ? 363 VAL A N 1 ATOM 2769 C CA . VAL A 1 363 ? 10.219 -6.972 39.317 1.00 35.93 ? 363 VAL A CA 1 ATOM 2770 C C . VAL A 1 363 ? 9.591 -8.390 39.264 1.00 35.59 ? 363 VAL A C 1 ATOM 2771 O O . VAL A 1 363 ? 10.258 -9.390 39.591 1.00 34.96 ? 363 VAL A O 1 ATOM 2772 C CB . VAL A 1 363 ? 11.188 -6.883 38.116 1.00 36.11 ? 363 VAL A CB 1 ATOM 2773 C CG1 . VAL A 1 363 ? 10.433 -7.076 36.805 1.00 37.08 ? 363 VAL A CG1 1 ATOM 2774 C CG2 . VAL A 1 363 ? 11.929 -5.565 38.109 1.00 36.24 ? 363 VAL A CG2 1 ATOM 2775 N N . GLU A 1 364 ? 8.321 -8.461 38.846 1.00 34.62 ? 364 GLU A N 1 ATOM 2776 C CA . GLU A 1 364 ? 7.654 -9.745 38.550 1.00 34.15 ? 364 GLU A CA 1 ATOM 2777 C C . GLU A 1 364 ? 7.201 -9.783 37.092 1.00 33.71 ? 364 GLU A C 1 ATOM 2778 O O . GLU A 1 364 ? 6.408 -8.923 36.657 1.00 34.18 ? 364 GLU A O 1 ATOM 2779 C CB . GLU A 1 364 ? 6.463 -10.014 39.497 1.00 33.49 ? 364 GLU A CB 1 ATOM 2780 C CG . GLU A 1 364 ? 6.892 -10.073 40.954 1.00 34.16 ? 364 GLU A CG 1 ATOM 2781 C CD . GLU A 1 364 ? 5.802 -10.482 41.955 1.00 35.50 ? 364 GLU A CD 1 ATOM 2782 O OE1 . GLU A 1 364 ? 6.153 -11.218 42.902 1.00 38.95 ? 364 GLU A OE1 1 ATOM 2783 O OE2 . GLU A 1 364 ? 4.624 -10.077 41.854 1.00 33.68 ? 364 GLU A OE2 1 ATOM 2784 N N . ASN A 1 365 ? 7.702 -10.769 36.340 1.00 32.65 ? 365 ASN A N 1 ATOM 2785 C CA . ASN A 1 365 ? 7.329 -10.931 34.929 1.00 31.75 ? 365 ASN A CA 1 ATOM 2786 C C . ASN A 1 365 ? 5.848 -11.282 34.737 1.00 31.59 ? 365 ASN A C 1 ATOM 2787 O O . ASN A 1 365 ? 5.103 -11.489 35.713 1.00 30.97 ? 365 ASN A O 1 ATOM 2788 C CB . ASN A 1 365 ? 8.266 -11.907 34.192 1.00 31.39 ? 365 ASN A CB 1 ATOM 2789 C CG . ASN A 1 365 ? 8.181 -13.335 34.714 1.00 32.21 ? 365 ASN A CG 1 ATOM 2790 O OD1 . ASN A 1 365 ? 7.084 -13.916 34.808 1.00 33.46 ? 365 ASN A OD1 1 ATOM 2791 N ND2 . ASN A 1 365 ? 9.344 -13.935 35.020 1.00 31.84 ? 365 ASN A ND2 1 ATOM 2792 N N . ILE A 1 366 ? 5.418 -11.355 33.479 1.00 31.38 ? 366 ILE A N 1 ATOM 2793 C CA . ILE A 1 366 ? 3.993 -11.531 33.210 1.00 30.80 ? 366 ILE A CA 1 ATOM 2794 C C . ILE A 1 366 ? 3.455 -12.921 33.595 1.00 30.86 ? 366 ILE A C 1 ATOM 2795 O O . ILE A 1 366 ? 2.236 -13.105 33.701 1.00 30.44 ? 366 ILE A O 1 ATOM 2796 C CB . ILE A 1 366 ? 3.618 -11.145 31.754 1.00 30.88 ? 366 ILE A CB 1 ATOM 2797 C CG1 . ILE A 1 366 ? 2.096 -10.969 31.624 1.00 30.12 ? 366 ILE A CG1 1 ATOM 2798 C CG2 . ILE A 1 366 ? 4.142 -12.182 30.775 1.00 28.23 ? 366 ILE A CG2 1 ATOM 2799 C CD1 . ILE A 1 366 ? 1.509 -9.761 32.316 1.00 28.20 ? 366 ILE A CD1 1 ATOM 2800 N N . THR A 1 367 ? 4.364 -13.876 33.823 1.00 30.82 ? 367 THR A N 1 ATOM 2801 C CA . THR A 1 367 ? 3.993 -15.198 34.361 1.00 30.94 ? 367 THR A CA 1 ATOM 2802 C C . THR A 1 367 ? 3.750 -15.119 35.856 1.00 30.71 ? 367 THR A C 1 ATOM 2803 O O . THR A 1 367 ? 2.708 -15.529 36.353 1.00 30.55 ? 367 THR A O 1 ATOM 2804 C CB . THR A 1 367 ? 5.090 -16.221 34.096 1.00 31.08 ? 367 THR A CB 1 ATOM 2805 O OG1 . THR A 1 367 ? 5.466 -16.129 32.718 1.00 31.35 ? 367 THR A OG1 1 ATOM 2806 C CG2 . THR A 1 367 ? 4.612 -17.652 34.434 1.00 32.03 ? 367 THR A CG2 1 ATOM 2807 N N . GLN A 1 368 ? 4.720 -14.553 36.572 1.00 30.73 ? 368 GLN A N 1 ATOM 2808 C CA . GLN A 1 368 ? 4.618 -14.434 38.028 1.00 29.78 ? 368 GLN A CA 1 ATOM 2809 C C . GLN A 1 368 ? 3.326 -13.710 38.381 1.00 29.04 ? 368 GLN A C 1 ATOM 2810 O O . GLN A 1 368 ? 2.655 -14.100 39.343 1.00 28.81 ? 368 GLN A O 1 ATOM 2811 C CB . GLN A 1 368 ? 5.854 -13.753 38.624 1.00 29.81 ? 368 GLN A CB 1 ATOM 2812 C CG . GLN A 1 368 ? 7.167 -14.341 38.103 1.00 31.28 ? 368 GLN A CG 1 ATOM 2813 C CD . GLN A 1 368 ? 8.409 -13.610 38.619 1.00 32.34 ? 368 GLN A CD 1 ATOM 2814 O OE1 . GLN A 1 368 ? 9.104 -12.921 37.872 1.00 30.82 ? 368 GLN A OE1 1 ATOM 2815 N NE2 . GLN A 1 368 ? 8.699 -13.781 39.898 1.00 33.87 ? 368 GLN A NE2 1 ATOM 2816 N N . THR A 1 369 ? 2.933 -12.714 37.575 1.00 27.72 ? 369 THR A N 1 ATOM 2817 C CA . THR A 1 369 ? 1.698 -11.959 37.868 1.00 26.72 ? 369 THR A CA 1 ATOM 2818 C C . THR A 1 369 ? 0.395 -12.580 37.268 1.00 26.30 ? 369 THR A C 1 ATOM 2819 O O . THR A 1 369 ? -0.713 -12.005 37.384 1.00 25.52 ? 369 THR A O 1 ATOM 2820 C CB . THR A 1 369 ? 1.827 -10.446 37.529 1.00 26.30 ? 369 THR A CB 1 ATOM 2821 O OG1 . THR A 1 369 ? 1.985 -10.283 36.115 1.00 27.35 ? 369 THR A OG1 1 ATOM 2822 C CG2 . THR A 1 369 ? 2.996 -9.841 38.216 1.00 24.34 ? 369 THR A CG2 1 ATOM 2823 N N . ASP A 1 370 ? 0.545 -13.760 36.637 1.00 26.55 ? 370 ASP A N 1 ATOM 2824 C CA . ASP A 1 370 ? -0.561 -14.515 36.005 1.00 24.88 ? 370 ASP A CA 1 ATOM 2825 C C . ASP A 1 370 ? -1.342 -13.596 35.031 1.00 24.37 ? 370 ASP A C 1 ATOM 2826 O O . ASP A 1 370 ? -2.591 -13.527 35.037 1.00 23.90 ? 370 ASP A O 1 ATOM 2827 C CB . ASP A 1 370 ? -1.482 -15.124 37.064 1.00 25.06 ? 370 ASP A CB 1 ATOM 2828 C CG . ASP A 1 370 ? -2.438 -16.152 36.494 1.00 27.72 ? 370 ASP A CG 1 ATOM 2829 O OD1 . ASP A 1 370 ? -1.976 -16.953 35.656 1.00 30.29 ? 370 ASP A OD1 1 ATOM 2830 O OD2 . ASP A 1 370 ? -3.643 -16.187 36.895 1.00 29.03 ? 370 ASP A OD2 1 ATOM 2831 N N . GLY A 1 371 ? -0.601 -12.866 34.211 1.00 22.53 ? 371 GLY A N 1 ATOM 2832 C CA . GLY A 1 371 ? -1.238 -12.039 33.198 1.00 21.94 ? 371 GLY A CA 1 ATOM 2833 C C . GLY A 1 371 ? -1.637 -10.626 33.584 1.00 20.84 ? 371 GLY A C 1 ATOM 2834 O O . GLY A 1 371 ? -2.285 -9.954 32.831 1.00 20.92 ? 371 GLY A O 1 ATOM 2835 N N . PHE A 1 372 ? -1.224 -10.145 34.741 1.00 20.28 ? 372 PHE A N 1 ATOM 2836 C CA . PHE A 1 372 ? -1.539 -8.765 35.077 1.00 19.01 ? 372 PHE A CA 1 ATOM 2837 C C . PHE A 1 372 ? -0.396 -7.805 34.875 1.00 18.77 ? 372 PHE A C 1 ATOM 2838 O O . PHE A 1 372 ? 0.720 -8.040 35.348 1.00 18.80 ? 372 PHE A O 1 ATOM 2839 C CB . PHE A 1 372 ? -2.028 -8.581 36.513 1.00 19.22 ? 372 PHE A CB 1 ATOM 2840 C CG . PHE A 1 372 ? -2.255 -7.166 36.827 1.00 18.01 ? 372 PHE A CG 1 ATOM 2841 C CD1 . PHE A 1 372 ? -3.433 -6.552 36.431 1.00 18.27 ? 372 PHE A CD1 1 ATOM 2842 C CD2 . PHE A 1 372 ? -1.244 -6.405 37.393 1.00 18.26 ? 372 PHE A CD2 1 ATOM 2843 C CE1 . PHE A 1 372 ? -3.616 -5.209 36.640 1.00 18.37 ? 372 PHE A CE1 1 ATOM 2844 C CE2 . PHE A 1 372 ? -1.410 -5.075 37.607 1.00 17.24 ? 372 PHE A CE2 1 ATOM 2845 C CZ . PHE A 1 372 ? -2.592 -4.459 37.229 1.00 18.11 ? 372 PHE A CZ 1 ATOM 2846 N N . SER A 1 373 ? -0.676 -6.722 34.163 1.00 18.10 ? 373 SER A N 1 ATOM 2847 C CA . SER A 1 373 ? 0.213 -5.583 34.118 1.00 17.88 ? 373 SER A CA 1 ATOM 2848 C C . SER A 1 373 ? -0.587 -4.418 33.589 1.00 17.34 ? 373 SER A C 1 ATOM 2849 O O . SER A 1 373 ? -1.603 -4.621 32.921 1.00 17.62 ? 373 SER A O 1 ATOM 2850 C CB . SER A 1 373 ? 1.430 -5.843 33.225 1.00 18.28 ? 373 SER A CB 1 ATOM 2851 O OG . SER A 1 373 ? 1.120 -5.678 31.856 1.00 17.89 ? 373 SER A OG 1 ATOM 2852 N N . SER A 1 374 ? -0.144 -3.201 33.879 1.00 16.07 ? 374 SER A N 1 ATOM 2853 C CA . SER A 1 374 ? -0.815 -2.048 33.327 1.00 16.57 ? 374 SER A CA 1 ATOM 2854 C C . SER A 1 374 ? -0.965 -2.168 31.842 1.00 16.19 ? 374 SER A C 1 ATOM 2855 O O . SER A 1 374 ? -2.050 -1.947 31.307 1.00 16.80 ? 374 SER A O 1 ATOM 2856 C CB . SER A 1 374 ? -0.028 -0.800 33.593 1.00 15.84 ? 374 SER A CB 1 ATOM 2857 O OG . SER A 1 374 ? -0.334 -0.332 34.875 1.00 21.54 ? 374 SER A OG 1 ATOM 2858 N N . ALA A 1 375 ? 0.155 -2.474 31.194 1.00 15.45 ? 375 ALA A N 1 ATOM 2859 C CA . ALA A 1 375 ? 0.267 -2.459 29.758 1.00 15.78 ? 375 ALA A CA 1 ATOM 2860 C C . ALA A 1 375 ? -0.575 -3.568 29.107 1.00 15.32 ? 375 ALA A C 1 ATOM 2861 O O . ALA A 1 375 ? -1.064 -3.376 27.987 1.00 15.79 ? 375 ALA A O 1 ATOM 2862 C CB . ALA A 1 375 ? 1.787 -2.575 29.322 1.00 15.91 ? 375 ALA A CB 1 ATOM 2863 N N . TRP A 1 376 ? -0.733 -4.695 29.803 1.00 13.61 ? 376 TRP A N 1 ATOM 2864 C CA . TRP A 1 376 ? -1.593 -5.779 29.345 1.00 14.55 ? 376 TRP A CA 1 ATOM 2865 C C . TRP A 1 376 ? -3.074 -5.542 29.691 1.00 14.90 ? 376 TRP A C 1 ATOM 2866 O O . TRP A 1 376 ? -3.931 -6.299 29.254 1.00 15.72 ? 376 TRP A O 1 ATOM 2867 C CB . TRP A 1 376 ? -1.115 -7.140 29.924 1.00 12.60 ? 376 TRP A CB 1 ATOM 2868 C CG . TRP A 1 376 ? 0.073 -7.692 29.188 1.00 14.54 ? 376 TRP A CG 1 ATOM 2869 C CD1 . TRP A 1 376 ? 1.142 -6.983 28.655 1.00 15.45 ? 376 TRP A CD1 1 ATOM 2870 C CD2 . TRP A 1 376 ? 0.314 -9.065 28.870 1.00 14.46 ? 376 TRP A CD2 1 ATOM 2871 N NE1 . TRP A 1 376 ? 2.005 -7.838 28.029 1.00 16.07 ? 376 TRP A NE1 1 ATOM 2872 C CE2 . TRP A 1 376 ? 1.524 -9.121 28.151 1.00 14.24 ? 376 TRP A CE2 1 ATOM 2873 C CE3 . TRP A 1 376 ? -0.396 -10.261 29.120 1.00 14.38 ? 376 TRP A CE3 1 ATOM 2874 C CZ2 . TRP A 1 376 ? 2.049 -10.324 27.666 1.00 14.91 ? 376 TRP A CZ2 1 ATOM 2875 C CZ3 . TRP A 1 376 ? 0.130 -11.454 28.669 1.00 16.06 ? 376 TRP A CZ3 1 ATOM 2876 C CH2 . TRP A 1 376 ? 1.348 -11.481 27.944 1.00 17.44 ? 376 TRP A CH2 1 ATOM 2877 N N . THR A 1 377 ? -3.394 -4.518 30.466 1.00 14.88 ? 377 THR A N 1 ATOM 2878 C CA . THR A 1 377 ? -4.800 -4.352 30.851 1.00 15.85 ? 377 THR A CA 1 ATOM 2879 C C . THR A 1 377 ? -5.365 -2.994 30.442 1.00 15.89 ? 377 THR A C 1 ATOM 2880 O O . THR A 1 377 ? -6.354 -2.922 29.706 1.00 16.86 ? 377 THR A O 1 ATOM 2881 C CB . THR A 1 377 ? -5.052 -4.639 32.360 1.00 15.91 ? 377 THR A CB 1 ATOM 2882 O OG1 . THR A 1 377 ? -4.300 -3.708 33.133 1.00 17.51 ? 377 THR A OG1 1 ATOM 2883 C CG2 . THR A 1 377 ? -4.557 -6.028 32.751 1.00 15.63 ? 377 THR A CG2 1 ATOM 2884 N N . VAL A 1 378 ? -4.737 -1.914 30.896 1.00 16.20 ? 378 VAL A N 1 ATOM 2885 C CA . VAL A 1 378 ? -5.194 -0.580 30.565 1.00 14.99 ? 378 VAL A CA 1 ATOM 2886 C C . VAL A 1 378 ? -4.223 0.274 29.781 1.00 15.60 ? 378 VAL A C 1 ATOM 2887 O O . VAL A 1 378 ? -3.914 1.392 30.199 1.00 15.10 ? 378 VAL A O 1 ATOM 2888 C CB . VAL A 1 378 ? -5.543 0.142 31.822 1.00 15.99 ? 378 VAL A CB 1 ATOM 2889 C CG1 . VAL A 1 378 ? -6.626 -0.588 32.481 1.00 13.25 ? 378 VAL A CG1 1 ATOM 2890 C CG2 . VAL A 1 378 ? -4.253 0.263 32.802 1.00 16.09 ? 378 VAL A CG2 1 ATOM 2891 N N . PRO A 1 379 ? -3.782 -0.203 28.605 1.00 16.10 ? 379 PRO A N 1 ATOM 2892 C CA . PRO A 1 379 ? -2.959 0.680 27.785 1.00 16.78 ? 379 PRO A CA 1 ATOM 2893 C C . PRO A 1 379 ? -3.805 1.786 27.217 1.00 17.73 ? 379 PRO A C 1 ATOM 2894 O O . PRO A 1 379 ? -5.020 1.810 27.473 1.00 18.81 ? 379 PRO A O 1 ATOM 2895 C CB . PRO A 1 379 ? -2.489 -0.231 26.648 1.00 17.47 ? 379 PRO A CB 1 ATOM 2896 C CG . PRO A 1 379 ? -3.501 -1.379 26.640 1.00 16.97 ? 379 PRO A CG 1 ATOM 2897 C CD . PRO A 1 379 ? -3.853 -1.570 28.061 1.00 15.74 ? 379 PRO A CD 1 ATOM 2898 N N . PHE A 1 380 ? -3.203 2.700 26.465 1.00 17.66 ? 380 PHE A N 1 ATOM 2899 C CA . PHE A 1 380 ? -4.026 3.646 25.718 1.00 18.95 ? 380 PHE A CA 1 ATOM 2900 C C . PHE A 1 380 ? -4.975 2.833 24.802 1.00 19.33 ? 380 PHE A C 1 ATOM 2901 O O . PHE A 1 380 ? -4.530 1.833 24.155 1.00 18.94 ? 380 PHE A O 1 ATOM 2902 C CB . PHE A 1 380 ? -3.173 4.582 24.848 1.00 18.53 ? 380 PHE A CB 1 ATOM 2903 C CG . PHE A 1 380 ? -2.525 5.691 25.604 1.00 19.33 ? 380 PHE A CG 1 ATOM 2904 C CD1 . PHE A 1 380 ? -3.251 6.461 26.480 1.00 19.05 ? 380 PHE A CD1 1 ATOM 2905 C CD2 . PHE A 1 380 ? -1.173 5.989 25.402 1.00 20.81 ? 380 PHE A CD2 1 ATOM 2906 C CE1 . PHE A 1 380 ? -2.656 7.497 27.158 1.00 20.11 ? 380 PHE A CE1 1 ATOM 2907 C CE2 . PHE A 1 380 ? -0.574 7.035 26.065 1.00 22.57 ? 380 PHE A CE2 1 ATOM 2908 C CZ . PHE A 1 380 ? -1.321 7.796 26.950 1.00 20.44 ? 380 PHE A CZ 1 ATOM 2909 N N . ALA A 1 381 ? -6.259 3.246 24.765 1.00 18.99 ? 381 ALA A N 1 ATOM 2910 C CA . ALA A 1 381 ? -7.259 2.618 23.900 1.00 18.30 ? 381 ALA A CA 1 ATOM 2911 C C . ALA A 1 381 ? -7.543 1.122 24.233 1.00 17.97 ? 381 ALA A C 1 ATOM 2912 O O . ALA A 1 381 ? -8.035 0.378 23.410 1.00 18.41 ? 381 ALA A O 1 ATOM 2913 C CB . ALA A 1 381 ? -6.802 2.767 22.455 1.00 17.32 ? 381 ALA A CB 1 ATOM 2914 N N . SER A 1 382 ? -7.227 0.686 25.439 1.00 17.50 ? 382 SER A N 1 ATOM 2915 C CA . SER A 1 382 ? -7.525 -0.664 25.879 1.00 17.05 ? 382 SER A CA 1 ATOM 2916 C C . SER A 1 382 ? -8.978 -1.019 25.643 1.00 17.14 ? 382 SER A C 1 ATOM 2917 O O . SER A 1 382 ? -9.880 -0.142 25.628 1.00 16.86 ? 382 SER A O 1 ATOM 2918 C CB . SER A 1 382 ? -7.283 -0.789 27.374 1.00 16.81 ? 382 SER A CB 1 ATOM 2919 O OG . SER A 1 382 ? -8.351 -0.181 28.085 1.00 18.87 ? 382 SER A OG 1 ATOM 2920 N N . ARG A 1 383 ? -9.229 -2.320 25.551 1.00 17.05 ? 383 ARG A N 1 ATOM 2921 C CA . ARG A 1 383 ? -10.622 -2.805 25.466 1.00 17.53 ? 383 ARG A CA 1 ATOM 2922 C C . ARG A 1 383 ? -10.863 -4.123 26.235 1.00 17.78 ? 383 ARG A C 1 ATOM 2923 O O . ARG A 1 383 ? -9.987 -5.035 26.274 1.00 17.31 ? 383 ARG A O 1 ATOM 2924 C CB . ARG A 1 383 ? -11.120 -2.882 23.989 1.00 17.20 ? 383 ARG A CB 1 ATOM 2925 C CG . ARG A 1 383 ? -10.441 -3.946 23.088 1.00 16.77 ? 383 ARG A CG 1 ATOM 2926 C CD . ARG A 1 383 ? -8.945 -3.744 22.800 1.00 17.24 ? 383 ARG A CD 1 ATOM 2927 N NE . ARG A 1 383 ? -8.590 -2.411 22.302 1.00 17.61 ? 383 ARG A NE 1 ATOM 2928 C CZ . ARG A 1 383 ? -8.388 -2.106 21.025 1.00 15.99 ? 383 ARG A CZ 1 ATOM 2929 N NH1 . ARG A 1 383 ? -8.561 -3.034 20.093 1.00 16.57 ? 383 ARG A NH1 1 ATOM 2930 N NH2 . ARG A 1 383 ? -8.040 -0.877 20.681 1.00 12.75 ? 383 ARG A NH2 1 ATOM 2931 N N . LEU A 1 384 ? -12.029 -4.179 26.875 1.00 16.56 ? 384 LEU A N 1 ATOM 2932 C CA . LEU A 1 384 ? -12.508 -5.398 27.447 1.00 17.36 ? 384 LEU A CA 1 ATOM 2933 C C . LEU A 1 384 ? -13.698 -5.828 26.636 1.00 17.48 ? 384 LEU A C 1 ATOM 2934 O O . LEU A 1 384 ? -14.604 -4.991 26.422 1.00 18.22 ? 384 LEU A O 1 ATOM 2935 C CB . LEU A 1 384 ? -13.009 -5.107 28.878 1.00 18.66 ? 384 LEU A CB 1 ATOM 2936 C CG . LEU A 1 384 ? -13.932 -6.086 29.654 1.00 18.13 ? 384 LEU A CG 1 ATOM 2937 C CD1 . LEU A 1 384 ? -13.088 -7.271 30.282 1.00 19.97 ? 384 LEU A CD1 1 ATOM 2938 C CD2 . LEU A 1 384 ? -14.713 -5.369 30.720 1.00 12.16 ? 384 LEU A CD2 1 ATOM 2939 N N . TYR A 1 385 ? -13.764 -7.104 26.229 1.00 16.77 ? 385 TYR A N 1 ATOM 2940 C CA . TYR A 1 385 ? -15.005 -7.647 25.629 1.00 15.95 ? 385 TYR A CA 1 ATOM 2941 C C . TYR A 1 385 ? -15.640 -8.717 26.528 1.00 16.57 ? 385 TYR A C 1 ATOM 2942 O O . TYR A 1 385 ? -15.012 -9.752 26.851 1.00 16.59 ? 385 TYR A O 1 ATOM 2943 C CB . TYR A 1 385 ? -14.791 -8.311 24.264 1.00 16.18 ? 385 TYR A CB 1 ATOM 2944 C CG . TYR A 1 385 ? -14.094 -7.531 23.157 1.00 15.85 ? 385 TYR A CG 1 ATOM 2945 C CD1 . TYR A 1 385 ? -14.362 -6.158 22.928 1.00 14.99 ? 385 TYR A CD1 1 ATOM 2946 C CD2 . TYR A 1 385 ? -13.216 -8.175 22.301 1.00 15.85 ? 385 TYR A CD2 1 ATOM 2947 C CE1 . TYR A 1 385 ? -13.728 -5.458 21.909 1.00 14.70 ? 385 TYR A CE1 1 ATOM 2948 C CE2 . TYR A 1 385 ? -12.575 -7.484 21.252 1.00 17.78 ? 385 TYR A CE2 1 ATOM 2949 C CZ . TYR A 1 385 ? -12.846 -6.138 21.063 1.00 16.80 ? 385 TYR A CZ 1 ATOM 2950 O OH . TYR A 1 385 ? -12.218 -5.488 20.054 1.00 16.02 ? 385 TYR A OH 1 ATOM 2951 N N . VAL A 1 386 ? -16.882 -8.491 26.934 1.00 16.07 ? 386 VAL A N 1 ATOM 2952 C CA . VAL A 1 386 ? -17.596 -9.551 27.555 1.00 16.38 ? 386 VAL A CA 1 ATOM 2953 C C . VAL A 1 386 ? -18.493 -10.209 26.471 1.00 18.26 ? 386 VAL A C 1 ATOM 2954 O O . VAL A 1 386 ? -19.239 -9.499 25.736 1.00 18.49 ? 386 VAL A O 1 ATOM 2955 C CB . VAL A 1 386 ? -18.417 -9.023 28.724 1.00 16.81 ? 386 VAL A CB 1 ATOM 2956 C CG1 . VAL A 1 386 ? -19.259 -10.157 29.363 1.00 14.95 ? 386 VAL A CG1 1 ATOM 2957 C CG2 . VAL A 1 386 ? -17.502 -8.335 29.774 1.00 14.28 ? 386 VAL A CG2 1 ATOM 2958 N N . GLU A 1 387 ? -18.391 -11.534 26.308 1.00 18.44 ? 387 GLU A N 1 ATOM 2959 C CA . GLU A 1 387 ? -19.365 -12.229 25.434 1.00 19.97 ? 387 GLU A CA 1 ATOM 2960 C C . GLU A 1 387 ? -20.205 -13.238 26.162 1.00 20.21 ? 387 GLU A C 1 ATOM 2961 O O . GLU A 1 387 ? -19.864 -13.758 27.227 1.00 20.67 ? 387 GLU A O 1 ATOM 2962 C CB . GLU A 1 387 ? -18.756 -12.834 24.149 1.00 18.70 ? 387 GLU A CB 1 ATOM 2963 C CG . GLU A 1 387 ? -17.316 -12.750 24.154 1.00 21.56 ? 387 GLU A CG 1 ATOM 2964 C CD . GLU A 1 387 ? -16.651 -13.398 22.993 1.00 21.11 ? 387 GLU A CD 1 ATOM 2965 O OE1 . GLU A 1 387 ? -16.361 -12.661 22.006 1.00 18.47 ? 387 GLU A OE1 1 ATOM 2966 O OE2 . GLU A 1 387 ? -16.329 -14.615 23.144 1.00 20.06 ? 387 GLU A OE2 1 ATOM 2967 N N . MET A 1 388 ? -21.340 -13.474 25.564 1.00 21.28 ? 388 MET A N 1 ATOM 2968 C CA . MET A 1 388 ? -22.191 -14.541 25.958 1.00 22.43 ? 388 MET A CA 1 ATOM 2969 C C . MET A 1 388 ? -22.449 -15.291 24.655 1.00 22.64 ? 388 MET A C 1 ATOM 2970 O O . MET A 1 388 ? -22.700 -14.671 23.643 1.00 22.77 ? 388 MET A O 1 ATOM 2971 C CB . MET A 1 388 ? -23.429 -13.906 26.562 1.00 22.20 ? 388 MET A CB 1 ATOM 2972 C CG . MET A 1 388 ? -24.330 -14.809 27.329 1.00 24.44 ? 388 MET A CG 1 ATOM 2973 S SD . MET A 1 388 ? -25.077 -13.924 28.702 1.00 23.79 ? 388 MET A SD 1 ATOM 2974 C CE . MET A 1 388 ? -26.167 -12.812 27.848 1.00 24.91 ? 388 MET A CE 1 ATOM 2975 N N . MET A 1 389 ? -22.331 -16.612 24.658 1.00 24.03 ? 389 MET A N 1 ATOM 2976 C CA . MET A 1 389 ? -22.543 -17.414 23.449 1.00 25.37 ? 389 MET A CA 1 ATOM 2977 C C . MET A 1 389 ? -23.412 -18.575 23.757 1.00 27.35 ? 389 MET A C 1 ATOM 2978 O O . MET A 1 389 ? -23.463 -19.044 24.894 1.00 27.45 ? 389 MET A O 1 ATOM 2979 C CB . MET A 1 389 ? -21.220 -17.964 22.867 1.00 24.91 ? 389 MET A CB 1 ATOM 2980 C CG . MET A 1 389 ? -20.425 -18.882 23.774 1.00 22.51 ? 389 MET A CG 1 ATOM 2981 S SD . MET A 1 389 ? -18.803 -19.451 23.097 1.00 24.37 ? 389 MET A SD 1 ATOM 2982 C CE . MET A 1 389 ? -18.000 -17.891 22.691 1.00 24.02 ? 389 MET A CE 1 ATOM 2983 N N . GLN A 1 390 ? -24.075 -19.064 22.726 1.00 29.38 ? 390 GLN A N 1 ATOM 2984 C CA . GLN A 1 390 ? -24.905 -20.237 22.861 1.00 31.80 ? 390 GLN A CA 1 ATOM 2985 C C . GLN A 1 390 ? -24.283 -21.332 22.054 1.00 32.71 ? 390 GLN A C 1 ATOM 2986 O O . GLN A 1 390 ? -23.921 -21.130 20.913 1.00 32.97 ? 390 GLN A O 1 ATOM 2987 C CB . GLN A 1 390 ? -26.317 -19.985 22.381 1.00 31.73 ? 390 GLN A CB 1 ATOM 2988 C CG . GLN A 1 390 ? -27.271 -20.777 23.177 1.00 34.28 ? 390 GLN A CG 1 ATOM 2989 C CD . GLN A 1 390 ? -27.673 -20.053 24.415 1.00 37.92 ? 390 GLN A CD 1 ATOM 2990 O OE1 . GLN A 1 390 ? -28.474 -20.558 25.178 1.00 42.02 ? 390 GLN A OE1 1 ATOM 2991 N NE2 . GLN A 1 390 ? -27.157 -18.835 24.607 1.00 38.81 ? 390 GLN A NE2 1 ATOM 2992 N N . CYS A 1 391 ? -24.123 -22.486 22.667 1.00 34.88 ? 391 CYS A N 1 ATOM 2993 C CA . CYS A 1 391 ? -23.339 -23.531 22.042 1.00 37.70 ? 391 CYS A CA 1 ATOM 2994 C C . CYS A 1 391 ? -24.148 -24.773 21.803 1.00 39.89 ? 391 CYS A C 1 ATOM 2995 O O . CYS A 1 391 ? -25.212 -24.959 22.401 1.00 40.46 ? 391 CYS A O 1 ATOM 2996 C CB . CYS A 1 391 ? -22.100 -23.851 22.860 1.00 37.29 ? 391 CYS A CB 1 ATOM 2997 S SG . CYS A 1 391 ? -20.923 -22.502 22.840 1.00 35.76 ? 391 CYS A SG 1 ATOM 2998 N N . GLN A 1 392 ? -23.621 -25.611 20.911 1.00 42.95 ? 392 GLN A N 1 ATOM 2999 C CA . GLN A 1 392 ? -24.288 -26.829 20.451 1.00 45.33 ? 392 GLN A CA 1 ATOM 3000 C C . GLN A 1 392 ? -24.570 -27.768 21.599 1.00 45.99 ? 392 GLN A C 1 ATOM 3001 O O . GLN A 1 392 ? -25.719 -28.155 21.807 1.00 47.25 ? 392 GLN A O 1 ATOM 3002 C CB . GLN A 1 392 ? -23.460 -27.535 19.368 1.00 45.64 ? 392 GLN A CB 1 ATOM 3003 N N . ALA A 1 393 ? -23.543 -28.099 22.370 1.00 46.41 ? 393 ALA A N 1 ATOM 3004 C CA . ALA A 1 393 ? -23.686 -29.180 23.341 1.00 46.84 ? 393 ALA A CA 1 ATOM 3005 C C . ALA A 1 393 ? -24.492 -28.890 24.641 1.00 46.61 ? 393 ALA A C 1 ATOM 3006 O O . ALA A 1 393 ? -24.733 -29.815 25.431 1.00 46.29 ? 393 ALA A O 1 ATOM 3007 C CB . ALA A 1 393 ? -22.289 -29.787 23.653 1.00 47.31 ? 393 ALA A CB 1 ATOM 3008 N N . GLU A 1 394 ? -24.914 -27.628 24.841 1.00 46.30 ? 394 GLU A N 1 ATOM 3009 C CA . GLU A 1 394 ? -25.355 -27.123 26.171 1.00 45.31 ? 394 GLU A CA 1 ATOM 3010 C C . GLU A 1 394 ? -26.566 -26.164 26.143 1.00 44.46 ? 394 GLU A C 1 ATOM 3011 O O . GLU A 1 394 ? -26.632 -25.272 25.302 1.00 44.53 ? 394 GLU A O 1 ATOM 3012 C CB . GLU A 1 394 ? -24.155 -26.471 26.886 1.00 45.48 ? 394 GLU A CB 1 ATOM 3013 C CG . GLU A 1 394 ? -24.471 -25.491 28.035 1.00 46.72 ? 394 GLU A CG 1 ATOM 3014 C CD . GLU A 1 394 ? -24.658 -26.143 29.415 1.00 49.34 ? 394 GLU A CD 1 ATOM 3015 O OE1 . GLU A 1 394 ? -23.725 -26.829 29.903 1.00 49.10 ? 394 GLU A OE1 1 ATOM 3016 O OE2 . GLU A 1 394 ? -25.737 -25.929 30.028 1.00 49.61 ? 394 GLU A OE2 1 ATOM 3017 N N . GLN A 1 395 ? -27.501 -26.329 27.082 1.00 43.11 ? 395 GLN A N 1 ATOM 3018 C CA . GLN A 1 395 ? -28.726 -25.492 27.137 1.00 41.63 ? 395 GLN A CA 1 ATOM 3019 C C . GLN A 1 395 ? -28.495 -24.024 27.546 1.00 40.12 ? 395 GLN A C 1 ATOM 3020 O O . GLN A 1 395 ? -29.169 -23.124 27.048 1.00 39.73 ? 395 GLN A O 1 ATOM 3021 C CB . GLN A 1 395 ? -29.775 -26.124 28.068 1.00 42.03 ? 395 GLN A CB 1 ATOM 3022 N N . GLU A 1 396 ? -27.525 -23.800 28.434 1.00 37.62 ? 396 GLU A N 1 ATOM 3023 C CA . GLU A 1 396 ? -27.265 -22.490 29.053 1.00 35.17 ? 396 GLU A CA 1 ATOM 3024 C C . GLU A 1 396 ? -26.278 -21.592 28.293 1.00 32.65 ? 396 GLU A C 1 ATOM 3025 O O . GLU A 1 396 ? -25.356 -22.097 27.631 1.00 32.83 ? 396 GLU A O 1 ATOM 3026 C CB . GLU A 1 396 ? -26.676 -22.718 30.442 1.00 35.47 ? 396 GLU A CB 1 ATOM 3027 C CG . GLU A 1 396 ? -27.691 -22.816 31.573 1.00 38.32 ? 396 GLU A CG 1 ATOM 3028 C CD . GLU A 1 396 ? -27.036 -22.703 32.953 1.00 41.98 ? 396 GLU A CD 1 ATOM 3029 O OE1 . GLU A 1 396 ? -26.686 -21.543 33.351 1.00 43.68 ? 396 GLU A OE1 1 ATOM 3030 O OE2 . GLU A 1 396 ? -26.888 -23.770 33.613 1.00 39.38 ? 396 GLU A OE2 1 ATOM 3031 N N . PRO A 1 397 ? -26.419 -20.257 28.441 1.00 29.53 ? 397 PRO A N 1 ATOM 3032 C CA . PRO A 1 397 ? -25.422 -19.375 27.823 1.00 27.22 ? 397 PRO A CA 1 ATOM 3033 C C . PRO A 1 397 ? -24.066 -19.453 28.540 1.00 24.97 ? 397 PRO A C 1 ATOM 3034 O O . PRO A 1 397 ? -24.024 -19.553 29.739 1.00 24.13 ? 397 PRO A O 1 ATOM 3035 C CB . PRO A 1 397 ? -26.045 -17.974 27.957 1.00 26.88 ? 397 PRO A CB 1 ATOM 3036 C CG . PRO A 1 397 ? -27.316 -18.144 28.796 1.00 27.46 ? 397 PRO A CG 1 ATOM 3037 C CD . PRO A 1 397 ? -27.320 -19.525 29.354 1.00 29.27 ? 397 PRO A CD 1 ATOM 3038 N N . LEU A 1 398 ? -22.985 -19.423 27.792 1.00 22.90 ? 398 LEU A N 1 ATOM 3039 C CA . LEU A 1 398 ? -21.655 -19.510 28.328 1.00 21.98 ? 398 LEU A CA 1 ATOM 3040 C C . LEU A 1 398 ? -20.989 -18.108 28.249 1.00 22.12 ? 398 LEU A C 1 ATOM 3041 O O . LEU A 1 398 ? -21.013 -17.476 27.165 1.00 22.85 ? 398 LEU A O 1 ATOM 3042 C CB . LEU A 1 398 ? -20.850 -20.513 27.482 1.00 22.14 ? 398 LEU A CB 1 ATOM 3043 C CG . LEU A 1 398 ? -21.179 -22.022 27.467 1.00 20.47 ? 398 LEU A CG 1 ATOM 3044 C CD1 . LEU A 1 398 ? -19.964 -22.755 27.016 1.00 19.36 ? 398 LEU A CD1 1 ATOM 3045 C CD2 . LEU A 1 398 ? -21.564 -22.542 28.847 1.00 19.44 ? 398 LEU A CD2 1 ATOM 3046 N N . VAL A 1 399 ? -20.418 -17.604 29.358 1.00 19.86 ? 399 VAL A N 1 ATOM 3047 C CA . VAL A 1 399 ? -19.832 -16.279 29.359 1.00 17.85 ? 399 VAL A CA 1 ATOM 3048 C C . VAL A 1 399 ? -18.358 -16.393 29.021 1.00 18.45 ? 399 VAL A C 1 ATOM 3049 O O . VAL A 1 399 ? -17.674 -17.269 29.535 1.00 17.81 ? 399 VAL A O 1 ATOM 3050 C CB . VAL A 1 399 ? -19.938 -15.659 30.727 1.00 17.76 ? 399 VAL A CB 1 ATOM 3051 C CG1 . VAL A 1 399 ? -19.113 -14.393 30.791 1.00 17.95 ? 399 VAL A CG1 1 ATOM 3052 C CG2 . VAL A 1 399 ? -21.373 -15.367 31.090 1.00 16.08 ? 399 VAL A CG2 1 ATOM 3053 N N . ARG A 1 400 ? -17.843 -15.514 28.162 1.00 18.49 ? 400 ARG A N 1 ATOM 3054 C CA . ARG A 1 400 ? -16.395 -15.449 27.957 1.00 18.36 ? 400 ARG A CA 1 ATOM 3055 C C . ARG A 1 400 ? -15.922 -14.005 27.979 1.00 18.81 ? 400 ARG A C 1 ATOM 3056 O O . ARG A 1 400 ? -16.687 -13.105 27.596 1.00 19.63 ? 400 ARG A O 1 ATOM 3057 C CB . ARG A 1 400 ? -16.003 -16.136 26.672 1.00 18.58 ? 400 ARG A CB 1 ATOM 3058 C CG . ARG A 1 400 ? -14.561 -15.960 26.296 1.00 20.26 ? 400 ARG A CG 1 ATOM 3059 C CD . ARG A 1 400 ? -14.173 -16.822 25.084 1.00 20.06 ? 400 ARG A CD 1 ATOM 3060 N NE . ARG A 1 400 ? -14.564 -16.188 23.830 1.00 23.42 ? 400 ARG A NE 1 ATOM 3061 C CZ . ARG A 1 400 ? -14.140 -16.562 22.627 1.00 23.20 ? 400 ARG A CZ 1 ATOM 3062 N NH1 . ARG A 1 400 ? -13.296 -17.571 22.517 1.00 23.52 ? 400 ARG A NH1 1 ATOM 3063 N NH2 . ARG A 1 400 ? -14.551 -15.901 21.535 1.00 21.73 ? 400 ARG A NH2 1 ATOM 3064 N N . VAL A 1 401 ? -14.677 -13.787 28.422 1.00 18.42 ? 401 VAL A N 1 ATOM 3065 C CA . VAL A 1 401 ? -14.093 -12.454 28.605 1.00 17.44 ? 401 VAL A CA 1 ATOM 3066 C C . VAL A 1 401 ? -12.751 -12.339 27.892 1.00 17.45 ? 401 VAL A C 1 ATOM 3067 O O . VAL A 1 401 ? -11.896 -13.215 28.077 1.00 16.69 ? 401 VAL A O 1 ATOM 3068 C CB . VAL A 1 401 ? -13.892 -12.160 30.084 1.00 16.68 ? 401 VAL A CB 1 ATOM 3069 C CG1 . VAL A 1 401 ? -12.803 -11.148 30.275 1.00 17.89 ? 401 VAL A CG1 1 ATOM 3070 C CG2 . VAL A 1 401 ? -15.171 -11.614 30.697 1.00 16.94 ? 401 VAL A CG2 1 ATOM 3071 N N . LEU A 1 402 ? -12.561 -11.300 27.065 1.00 16.86 ? 402 LEU A N 1 ATOM 3072 C CA . LEU A 1 402 ? -11.208 -11.046 26.521 1.00 17.84 ? 402 LEU A CA 1 ATOM 3073 C C . LEU A 1 402 ? -10.661 -9.689 26.971 1.00 18.66 ? 402 LEU A C 1 ATOM 3074 O O . LEU A 1 402 ? -11.398 -8.700 27.063 1.00 20.16 ? 402 LEU A O 1 ATOM 3075 C CB . LEU A 1 402 ? -11.134 -11.186 24.994 1.00 17.70 ? 402 LEU A CB 1 ATOM 3076 C CG . LEU A 1 402 ? -11.683 -12.499 24.392 1.00 17.01 ? 402 LEU A CG 1 ATOM 3077 C CD1 . LEU A 1 402 ? -13.207 -12.469 24.363 1.00 11.18 ? 402 LEU A CD1 1 ATOM 3078 C CD2 . LEU A 1 402 ? -11.137 -12.704 22.993 1.00 13.70 ? 402 LEU A CD2 1 ATOM 3079 N N . VAL A 1 403 ? -9.368 -9.638 27.262 1.00 19.09 ? 403 VAL A N 1 ATOM 3080 C CA . VAL A 1 403 ? -8.730 -8.404 27.734 1.00 19.02 ? 403 VAL A CA 1 ATOM 3081 C C . VAL A 1 403 ? -7.590 -8.075 26.785 1.00 18.67 ? 403 VAL A C 1 ATOM 3082 O O . VAL A 1 403 ? -6.578 -8.748 26.763 1.00 18.55 ? 403 VAL A O 1 ATOM 3083 C CB . VAL A 1 403 ? -8.278 -8.561 29.221 1.00 19.02 ? 403 VAL A CB 1 ATOM 3084 C CG1 . VAL A 1 403 ? -7.448 -7.378 29.675 1.00 18.82 ? 403 VAL A CG1 1 ATOM 3085 C CG2 . VAL A 1 403 ? -9.536 -8.751 30.104 1.00 18.95 ? 403 VAL A CG2 1 ATOM 3086 N N . ASN A 1 404 ? -7.807 -7.055 25.963 1.00 19.52 ? 404 ASN A N 1 ATOM 3087 C CA . ASN A 1 404 ? -6.957 -6.730 24.800 1.00 19.43 ? 404 ASN A CA 1 ATOM 3088 C C . ASN A 1 404 ? -6.613 -7.891 23.895 1.00 20.51 ? 404 ASN A C 1 ATOM 3089 O O . ASN A 1 404 ? -5.467 -8.034 23.477 1.00 20.90 ? 404 ASN A O 1 ATOM 3090 C CB . ASN A 1 404 ? -5.708 -5.988 25.229 1.00 19.82 ? 404 ASN A CB 1 ATOM 3091 C CG . ASN A 1 404 ? -6.040 -4.694 25.947 1.00 19.64 ? 404 ASN A CG 1 ATOM 3092 O OD1 . ASN A 1 404 ? -6.552 -3.739 25.343 1.00 16.22 ? 404 ASN A OD1 1 ATOM 3093 N ND2 . ASN A 1 404 ? -5.812 -4.676 27.266 1.00 21.43 ? 404 ASN A ND2 1 ATOM 3094 N N . ASP A 1 405 ? -7.629 -8.708 23.588 1.00 21.16 ? 405 ASP A N 1 ATOM 3095 C CA . ASP A 1 405 ? -7.570 -9.793 22.581 1.00 21.72 ? 405 ASP A CA 1 ATOM 3096 C C . ASP A 1 405 ? -7.019 -11.117 23.147 1.00 22.49 ? 405 ASP A C 1 ATOM 3097 O O . ASP A 1 405 ? -6.790 -12.069 22.401 1.00 23.01 ? 405 ASP A O 1 ATOM 3098 C CB . ASP A 1 405 ? -6.837 -9.386 21.292 1.00 20.23 ? 405 ASP A CB 1 ATOM 3099 C CG . ASP A 1 405 ? -7.397 -8.129 20.672 1.00 21.99 ? 405 ASP A CG 1 ATOM 3100 O OD1 . ASP A 1 405 ? -8.558 -7.777 20.995 1.00 23.41 ? 405 ASP A OD1 1 ATOM 3101 O OD2 . ASP A 1 405 ? -6.696 -7.482 19.836 1.00 17.82 ? 405 ASP A OD2 1 ATOM 3102 N N . ARG A 1 406 ? -6.798 -11.135 24.467 1.00 23.34 ? 406 ARG A N 1 ATOM 3103 C CA . ARG A 1 406 ? -6.401 -12.315 25.251 1.00 22.75 ? 406 ARG A CA 1 ATOM 3104 C C . ARG A 1 406 ? -7.601 -12.875 26.004 1.00 22.51 ? 406 ARG A C 1 ATOM 3105 O O . ARG A 1 406 ? -8.291 -12.158 26.748 1.00 22.05 ? 406 ARG A O 1 ATOM 3106 C CB . ARG A 1 406 ? -5.345 -11.913 26.261 1.00 23.16 ? 406 ARG A CB 1 ATOM 3107 C CG . ARG A 1 406 ? -4.827 -13.062 27.110 1.00 25.34 ? 406 ARG A CG 1 ATOM 3108 C CD . ARG A 1 406 ? -3.839 -12.597 28.181 1.00 28.05 ? 406 ARG A CD 1 ATOM 3109 N NE . ARG A 1 406 ? -3.481 -13.700 29.085 1.00 31.79 ? 406 ARG A NE 1 ATOM 3110 C CZ . ARG A 1 406 ? -3.916 -13.837 30.345 1.00 34.16 ? 406 ARG A CZ 1 ATOM 3111 N NH1 . ARG A 1 406 ? -4.721 -12.932 30.891 1.00 32.67 ? 406 ARG A NH1 1 ATOM 3112 N NH2 . ARG A 1 406 ? -3.533 -14.887 31.080 1.00 36.76 ? 406 ARG A NH2 1 ATOM 3113 N N . VAL A 1 407 ? -7.881 -14.164 25.797 1.00 22.24 ? 407 VAL A N 1 ATOM 3114 C CA . VAL A 1 407 ? -8.921 -14.814 26.584 1.00 20.44 ? 407 VAL A CA 1 ATOM 3115 C C . VAL A 1 407 ? -8.393 -14.926 28.012 1.00 21.15 ? 407 VAL A C 1 ATOM 3116 O O . VAL A 1 407 ? -7.241 -15.320 28.230 1.00 21.25 ? 407 VAL A O 1 ATOM 3117 C CB . VAL A 1 407 ? -9.282 -16.207 26.046 1.00 20.56 ? 407 VAL A CB 1 ATOM 3118 C CG1 . VAL A 1 407 ? -10.427 -16.807 26.851 1.00 18.00 ? 407 VAL A CG1 1 ATOM 3119 C CG2 . VAL A 1 407 ? -9.670 -16.144 24.543 1.00 17.00 ? 407 VAL A CG2 1 ATOM 3120 N N . VAL A 1 408 ? -9.217 -14.545 28.974 1.00 20.48 ? 408 VAL A N 1 ATOM 3121 C CA . VAL A 1 408 ? -8.819 -14.532 30.351 1.00 20.32 ? 408 VAL A CA 1 ATOM 3122 C C . VAL A 1 408 ? -9.814 -15.429 31.020 1.00 20.63 ? 408 VAL A C 1 ATOM 3123 O O . VAL A 1 408 ? -11.004 -15.125 30.976 1.00 20.78 ? 408 VAL A O 1 ATOM 3124 C CB . VAL A 1 408 ? -8.797 -13.084 31.009 1.00 20.36 ? 408 VAL A CB 1 ATOM 3125 C CG1 . VAL A 1 408 ? -8.471 -13.184 32.503 1.00 20.11 ? 408 VAL A CG1 1 ATOM 3126 C CG2 . VAL A 1 408 ? -7.792 -12.194 30.332 1.00 18.58 ? 408 VAL A CG2 1 ATOM 3127 N N . PRO A 1 409 ? -9.336 -16.559 31.597 1.00 20.42 ? 409 PRO A N 1 ATOM 3128 C CA . PRO A 1 409 ? -10.210 -17.553 32.167 1.00 20.48 ? 409 PRO A CA 1 ATOM 3129 C C . PRO A 1 409 ? -10.927 -17.003 33.377 1.00 21.13 ? 409 PRO A C 1 ATOM 3130 O O . PRO A 1 409 ? -10.279 -16.536 34.319 1.00 22.37 ? 409 PRO A O 1 ATOM 3131 C CB . PRO A 1 409 ? -9.250 -18.674 32.622 1.00 20.40 ? 409 PRO A CB 1 ATOM 3132 C CG . PRO A 1 409 ? -8.001 -18.475 31.842 1.00 21.63 ? 409 PRO A CG 1 ATOM 3133 C CD . PRO A 1 409 ? -7.923 -16.984 31.601 1.00 20.43 ? 409 PRO A CD 1 ATOM 3134 N N . LEU A 1 410 ? -12.252 -17.106 33.388 1.00 20.95 ? 410 LEU A N 1 ATOM 3135 C CA . LEU A 1 410 ? -13.058 -16.683 34.545 1.00 21.02 ? 410 LEU A CA 1 ATOM 3136 C C . LEU A 1 410 ? -12.657 -17.352 35.885 1.00 21.24 ? 410 LEU A C 1 ATOM 3137 O O . LEU A 1 410 ? -12.119 -18.474 35.907 1.00 20.36 ? 410 LEU A O 1 ATOM 3138 C CB . LEU A 1 410 ? -14.533 -16.949 34.255 1.00 21.01 ? 410 LEU A CB 1 ATOM 3139 C CG . LEU A 1 410 ? -15.059 -16.366 32.932 1.00 20.68 ? 410 LEU A CG 1 ATOM 3140 C CD1 . LEU A 1 410 ? -16.564 -16.398 32.945 1.00 19.65 ? 410 LEU A CD1 1 ATOM 3141 C CD2 . LEU A 1 410 ? -14.523 -14.961 32.662 1.00 16.80 ? 410 LEU A CD2 1 ATOM 3142 N N . HIS A 1 411 ? -12.900 -16.640 36.986 1.00 20.74 ? 411 HIS A N 1 ATOM 3143 C CA . HIS A 1 411 ? -12.627 -17.171 38.317 1.00 20.66 ? 411 HIS A CA 1 ATOM 3144 C C . HIS A 1 411 ? -13.940 -17.118 39.049 1.00 20.48 ? 411 HIS A C 1 ATOM 3145 O O . HIS A 1 411 ? -14.858 -16.348 38.659 1.00 19.54 ? 411 HIS A O 1 ATOM 3146 C CB . HIS A 1 411 ? -11.555 -16.354 39.065 1.00 20.73 ? 411 HIS A CB 1 ATOM 3147 C CG . HIS A 1 411 ? -10.138 -16.651 38.634 1.00 21.14 ? 411 HIS A CG 1 ATOM 3148 N ND1 . HIS A 1 411 ? -9.488 -15.933 37.652 1.00 22.78 ? 411 HIS A ND1 1 ATOM 3149 C CD2 . HIS A 1 411 ? -9.249 -17.573 39.064 1.00 21.36 ? 411 HIS A CD2 1 ATOM 3150 C CE1 . HIS A 1 411 ? -8.267 -16.411 37.478 1.00 23.66 ? 411 HIS A CE1 1 ATOM 3151 N NE2 . HIS A 1 411 ? -8.097 -17.405 38.325 1.00 24.33 ? 411 HIS A NE2 1 ATOM 3152 N N . GLY A 1 412 ? -14.042 -17.959 40.080 1.00 19.89 ? 412 GLY A N 1 ATOM 3153 C CA . GLY A 1 412 ? -15.199 -17.963 40.976 1.00 19.05 ? 412 GLY A CA 1 ATOM 3154 C C . GLY A 1 412 ? -16.324 -18.841 40.475 1.00 19.37 ? 412 GLY A C 1 ATOM 3155 O O . GLY A 1 412 ? -17.428 -18.869 41.051 1.00 17.59 ? 412 GLY A O 1 ATOM 3156 N N . CYS A 1 413 ? -16.027 -19.573 39.396 1.00 20.45 ? 413 CYS A N 1 ATOM 3157 C CA . CYS A 1 413 ? -16.988 -20.500 38.767 1.00 21.43 ? 413 CYS A CA 1 ATOM 3158 C C . CYS A 1 413 ? -16.276 -21.636 38.023 1.00 21.62 ? 413 CYS A C 1 ATOM 3159 O O . CYS A 1 413 ? -15.063 -21.537 37.729 1.00 22.31 ? 413 CYS A O 1 ATOM 3160 C CB . CYS A 1 413 ? -17.928 -19.733 37.839 1.00 21.41 ? 413 CYS A CB 1 ATOM 3161 S SG . CYS A 1 413 ? -17.115 -18.796 36.543 1.00 22.31 ? 413 CYS A SG 1 ATOM 3162 N N . PRO A 1 414 ? -17.004 -22.730 37.726 1.00 22.11 ? 414 PRO A N 1 ATOM 3163 C CA . PRO A 1 414 ? -16.286 -23.860 37.089 1.00 22.13 ? 414 PRO A CA 1 ATOM 3164 C C . PRO A 1 414 ? -15.841 -23.556 35.650 1.00 22.37 ? 414 PRO A C 1 ATOM 3165 O O . PRO A 1 414 ? -16.538 -23.916 34.709 1.00 23.57 ? 414 PRO A O 1 ATOM 3166 C CB . PRO A 1 414 ? -17.309 -25.002 37.109 1.00 20.78 ? 414 PRO A CB 1 ATOM 3167 C CG . PRO A 1 414 ? -18.410 -24.556 38.121 1.00 21.89 ? 414 PRO A CG 1 ATOM 3168 C CD . PRO A 1 414 ? -18.410 -23.057 38.062 1.00 21.61 ? 414 PRO A CD 1 ATOM 3169 N N . VAL A 1 415 ? -14.687 -22.933 35.464 1.00 22.92 ? 415 VAL A N 1 ATOM 3170 C CA . VAL A 1 415 ? -14.205 -22.708 34.090 1.00 24.05 ? 415 VAL A CA 1 ATOM 3171 C C . VAL A 1 415 ? -14.015 -23.977 33.347 1.00 24.47 ? 415 VAL A C 1 ATOM 3172 O O . VAL A 1 415 ? -13.620 -24.971 33.940 1.00 25.81 ? 415 VAL A O 1 ATOM 3173 C CB . VAL A 1 415 ? -12.856 -21.949 33.942 1.00 24.49 ? 415 VAL A CB 1 ATOM 3174 C CG1 . VAL A 1 415 ? -13.114 -20.529 33.514 1.00 23.68 ? 415 VAL A CG1 1 ATOM 3175 C CG2 . VAL A 1 415 ? -11.907 -22.071 35.168 1.00 23.88 ? 415 VAL A CG2 1 ATOM 3176 N N . ASP A 1 416 ? -14.317 -23.944 32.058 1.00 24.85 ? 416 ASP A N 1 ATOM 3177 C CA . ASP A 1 416 ? -13.954 -25.021 31.133 1.00 25.33 ? 416 ASP A CA 1 ATOM 3178 C C . ASP A 1 416 ? -12.593 -24.696 30.497 1.00 25.50 ? 416 ASP A C 1 ATOM 3179 O O . ASP A 1 416 ? -11.987 -23.699 30.868 1.00 26.21 ? 416 ASP A O 1 ATOM 3180 C CB . ASP A 1 416 ? -15.089 -25.271 30.125 1.00 25.22 ? 416 ASP A CB 1 ATOM 3181 C CG . ASP A 1 416 ? -15.336 -24.093 29.166 1.00 26.69 ? 416 ASP A CG 1 ATOM 3182 O OD1 . ASP A 1 416 ? -14.364 -23.433 28.749 1.00 25.96 ? 416 ASP A OD1 1 ATOM 3183 O OD2 . ASP A 1 416 ? -16.523 -23.862 28.818 1.00 26.82 ? 416 ASP A OD2 1 ATOM 3184 N N . ALA A 1 417 ? -12.083 -25.523 29.593 1.00 26.29 ? 417 ALA A N 1 ATOM 3185 C CA . ALA A 1 417 ? -10.717 -25.304 29.041 1.00 27.21 ? 417 ALA A CA 1 ATOM 3186 C C . ALA A 1 417 ? -10.660 -24.166 28.028 1.00 27.64 ? 417 ALA A C 1 ATOM 3187 O O . ALA A 1 417 ? -9.556 -23.780 27.554 1.00 28.06 ? 417 ALA A O 1 ATOM 3188 C CB . ALA A 1 417 ? -10.168 -26.589 28.384 1.00 27.59 ? 417 ALA A CB 1 ATOM 3189 N N . LEU A 1 418 ? -11.847 -23.653 27.672 1.00 27.00 ? 418 LEU A N 1 ATOM 3190 C CA . LEU A 1 418 ? -11.950 -22.565 26.710 1.00 26.19 ? 418 LEU A CA 1 ATOM 3191 C C . LEU A 1 418 ? -12.099 -21.222 27.430 1.00 25.61 ? 418 LEU A C 1 ATOM 3192 O O . LEU A 1 418 ? -12.281 -20.165 26.784 1.00 25.29 ? 418 LEU A O 1 ATOM 3193 C CB . LEU A 1 418 ? -13.058 -22.842 25.691 1.00 25.96 ? 418 LEU A CB 1 ATOM 3194 C CG . LEU A 1 418 ? -12.826 -24.109 24.840 1.00 26.60 ? 418 LEU A CG 1 ATOM 3195 C CD1 . LEU A 1 418 ? -14.024 -24.422 23.989 1.00 24.80 ? 418 LEU A CD1 1 ATOM 3196 C CD2 . LEU A 1 418 ? -11.544 -24.042 23.973 1.00 25.44 ? 418 LEU A CD2 1 ATOM 3197 N N . GLY A 1 419 ? -11.966 -21.271 28.760 1.00 24.03 ? 419 GLY A N 1 ATOM 3198 C CA . GLY A 1 419 ? -12.012 -20.075 29.592 1.00 23.35 ? 419 GLY A CA 1 ATOM 3199 C C . GLY A 1 419 ? -13.391 -19.620 30.044 1.00 22.99 ? 419 GLY A C 1 ATOM 3200 O O . GLY A 1 419 ? -13.501 -18.570 30.665 1.00 22.25 ? 419 GLY A O 1 ATOM 3201 N N . ARG A 1 420 ? -14.429 -20.407 29.758 1.00 22.47 ? 420 ARG A N 1 ATOM 3202 C CA . ARG A 1 420 ? -15.815 -19.947 29.903 1.00 23.31 ? 420 ARG A CA 1 ATOM 3203 C C . ARG A 1 420 ? -16.520 -20.494 31.124 1.00 23.26 ? 420 ARG A C 1 ATOM 3204 O O . ARG A 1 420 ? -16.248 -21.593 31.589 1.00 24.96 ? 420 ARG A O 1 ATOM 3205 C CB . ARG A 1 420 ? -16.674 -20.340 28.675 1.00 23.28 ? 420 ARG A CB 1 ATOM 3206 C CG . ARG A 1 420 ? -16.050 -20.100 27.288 1.00 23.74 ? 420 ARG A CG 1 ATOM 3207 C CD . ARG A 1 420 ? -16.882 -20.788 26.150 1.00 24.71 ? 420 ARG A CD 1 ATOM 3208 N NE . ARG A 1 420 ? -16.918 -22.258 26.254 1.00 24.38 ? 420 ARG A NE 1 ATOM 3209 C CZ . ARG A 1 420 ? -17.160 -23.094 25.235 1.00 25.51 ? 420 ARG A CZ 1 ATOM 3210 N NH1 . ARG A 1 420 ? -17.395 -22.616 24.004 1.00 25.64 ? 420 ARG A NH1 1 ATOM 3211 N NH2 . ARG A 1 420 ? -17.172 -24.411 25.443 1.00 20.13 ? 420 ARG A NH2 1 ATOM 3212 N N . CYS A 1 421 ? -17.475 -19.763 31.633 1.00 23.37 ? 421 CYS A N 1 ATOM 3213 C CA . CYS A 1 421 ? -18.380 -20.371 32.617 1.00 24.00 ? 421 CYS A CA 1 ATOM 3214 C C . CYS A 1 421 ? -19.776 -20.245 32.126 1.00 23.33 ? 421 CYS A C 1 ATOM 3215 O O . CYS A 1 421 ? -20.078 -19.338 31.351 1.00 23.97 ? 421 CYS A O 1 ATOM 3216 C CB . CYS A 1 421 ? -18.312 -19.657 33.953 1.00 23.76 ? 421 CYS A CB 1 ATOM 3217 S SG . CYS A 1 421 ? -16.905 -20.101 34.972 1.00 27.56 ? 421 CYS A SG 1 ATOM 3218 N N . THR A 1 422 ? -20.662 -21.099 32.614 1.00 23.27 ? 422 THR A N 1 ATOM 3219 C CA . THR A 1 422 ? -22.076 -20.876 32.359 1.00 22.85 ? 422 THR A CA 1 ATOM 3220 C C . THR A 1 422 ? -22.472 -19.560 33.009 1.00 23.37 ? 422 THR A C 1 ATOM 3221 O O . THR A 1 422 ? -21.952 -19.212 34.060 1.00 24.29 ? 422 THR A O 1 ATOM 3222 C CB . THR A 1 422 ? -22.952 -21.983 32.917 1.00 22.77 ? 422 THR A CB 1 ATOM 3223 O OG1 . THR A 1 422 ? -23.026 -21.849 34.327 1.00 22.22 ? 422 THR A OG1 1 ATOM 3224 C CG2 . THR A 1 422 ? -22.442 -23.399 32.521 1.00 21.22 ? 422 THR A CG2 1 ATOM 3225 N N . ARG A 1 423 ? -23.408 -18.843 32.402 1.00 23.81 ? 423 ARG A N 1 ATOM 3226 C CA . ARG A 1 423 ? -23.843 -17.545 32.905 1.00 24.13 ? 423 ARG A CA 1 ATOM 3227 C C . ARG A 1 423 ? -24.305 -17.591 34.333 1.00 24.38 ? 423 ARG A C 1 ATOM 3228 O O . ARG A 1 423 ? -23.928 -16.710 35.117 1.00 24.30 ? 423 ARG A O 1 ATOM 3229 C CB . ARG A 1 423 ? -24.920 -16.933 32.013 1.00 23.76 ? 423 ARG A CB 1 ATOM 3230 C CG . ARG A 1 423 ? -25.334 -15.520 32.350 1.00 25.23 ? 423 ARG A CG 1 ATOM 3231 C CD . ARG A 1 423 ? -26.661 -15.468 33.138 1.00 27.92 ? 423 ARG A CD 1 ATOM 3232 N NE . ARG A 1 423 ? -27.686 -16.399 32.667 1.00 27.57 ? 423 ARG A NE 1 ATOM 3233 C CZ . ARG A 1 423 ? -28.600 -16.131 31.722 1.00 30.15 ? 423 ARG A CZ 1 ATOM 3234 N NH1 . ARG A 1 423 ? -28.627 -14.947 31.084 1.00 29.88 ? 423 ARG A NH1 1 ATOM 3235 N NH2 . ARG A 1 423 ? -29.497 -17.068 31.394 1.00 26.94 ? 423 ARG A NH2 1 ATOM 3236 N N . ASP A 1 424 ? -25.102 -18.602 34.684 1.00 25.17 ? 424 ASP A N 1 ATOM 3237 C CA . ASP A 1 424 ? -25.703 -18.658 36.048 1.00 25.80 ? 424 ASP A CA 1 ATOM 3238 C C . ASP A 1 424 ? -24.633 -18.785 37.116 1.00 25.23 ? 424 ASP A C 1 ATOM 3239 O O . ASP A 1 424 ? -24.738 -18.163 38.189 1.00 25.08 ? 424 ASP A O 1 ATOM 3240 C CB . ASP A 1 424 ? -26.732 -19.797 36.205 1.00 26.61 ? 424 ASP A CB 1 ATOM 3241 C CG . ASP A 1 424 ? -28.128 -19.417 35.706 1.00 30.30 ? 424 ASP A CG 1 ATOM 3242 O OD1 . ASP A 1 424 ? -28.422 -18.205 35.460 1.00 35.03 ? 424 ASP A OD1 1 ATOM 3243 O OD2 . ASP A 1 424 ? -28.958 -20.341 35.547 1.00 34.71 ? 424 ASP A OD2 1 ATOM 3244 N N . SER A 1 425 ? -23.592 -19.557 36.796 1.00 24.12 ? 425 SER A N 1 ATOM 3245 C CA . SER A 1 425 ? -22.518 -19.816 37.737 1.00 23.72 ? 425 SER A CA 1 ATOM 3246 C C . SER A 1 425 ? -21.513 -18.640 37.765 1.00 23.27 ? 425 SER A C 1 ATOM 3247 O O . SER A 1 425 ? -20.950 -18.303 38.807 1.00 23.82 ? 425 SER A O 1 ATOM 3248 C CB . SER A 1 425 ? -21.835 -21.147 37.423 1.00 22.85 ? 425 SER A CB 1 ATOM 3249 O OG . SER A 1 425 ? -20.949 -20.973 36.337 1.00 24.17 ? 425 SER A OG 1 ATOM 3250 N N . PHE A 1 426 ? -21.287 -18.007 36.628 1.00 22.73 ? 426 PHE A N 1 ATOM 3251 C CA . PHE A 1 426 ? -20.545 -16.748 36.617 1.00 21.85 ? 426 PHE A CA 1 ATOM 3252 C C . PHE A 1 426 ? -21.184 -15.691 37.524 1.00 22.04 ? 426 PHE A C 1 ATOM 3253 O O . PHE A 1 426 ? -20.482 -15.029 38.311 1.00 21.79 ? 426 PHE A O 1 ATOM 3254 C CB . PHE A 1 426 ? -20.404 -16.207 35.203 1.00 20.72 ? 426 PHE A CB 1 ATOM 3255 C CG . PHE A 1 426 ? -19.586 -14.984 35.126 1.00 19.79 ? 426 PHE A CG 1 ATOM 3256 C CD1 . PHE A 1 426 ? -18.234 -15.018 35.474 1.00 21.07 ? 426 PHE A CD1 1 ATOM 3257 C CD2 . PHE A 1 426 ? -20.163 -13.775 34.741 1.00 19.65 ? 426 PHE A CD2 1 ATOM 3258 C CE1 . PHE A 1 426 ? -17.453 -13.875 35.415 1.00 22.47 ? 426 PHE A CE1 1 ATOM 3259 C CE2 . PHE A 1 426 ? -19.380 -12.595 34.681 1.00 20.22 ? 426 PHE A CE2 1 ATOM 3260 C CZ . PHE A 1 426 ? -18.043 -12.639 35.002 1.00 21.10 ? 426 PHE A CZ 1 ATOM 3261 N N . VAL A 1 427 ? -22.500 -15.526 37.413 1.00 22.15 ? 427 VAL A N 1 ATOM 3262 C CA . VAL A 1 427 ? -23.186 -14.491 38.201 1.00 22.51 ? 427 VAL A CA 1 ATOM 3263 C C . VAL A 1 427 ? -23.062 -14.827 39.677 1.00 22.84 ? 427 VAL A C 1 ATOM 3264 O O . VAL A 1 427 ? -22.601 -14.015 40.501 1.00 23.66 ? 427 VAL A O 1 ATOM 3265 C CB . VAL A 1 427 ? -24.644 -14.294 37.740 1.00 22.44 ? 427 VAL A CB 1 ATOM 3266 C CG1 . VAL A 1 427 ? -25.481 -13.566 38.797 1.00 22.20 ? 427 VAL A CG1 1 ATOM 3267 C CG2 . VAL A 1 427 ? -24.666 -13.523 36.411 1.00 21.49 ? 427 VAL A CG2 1 ATOM 3268 N N . ARG A 1 428 ? -23.408 -16.059 40.002 1.00 23.81 ? 428 ARG A N 1 ATOM 3269 C CA . ARG A 1 428 ? -23.245 -16.590 41.352 1.00 24.27 ? 428 ARG A CA 1 ATOM 3270 C C . ARG A 1 428 ? -21.838 -16.358 41.919 1.00 23.70 ? 428 ARG A C 1 ATOM 3271 O O . ARG A 1 428 ? -21.720 -16.091 43.103 1.00 23.71 ? 428 ARG A O 1 ATOM 3272 C CB . ARG A 1 428 ? -23.620 -18.066 41.370 1.00 24.71 ? 428 ARG A CB 1 ATOM 3273 C CG . ARG A 1 428 ? -23.394 -18.820 42.685 1.00 29.78 ? 428 ARG A CG 1 ATOM 3274 C CD . ARG A 1 428 ? -22.839 -20.210 42.375 1.00 37.01 ? 428 ARG A CD 1 ATOM 3275 N NE . ARG A 1 428 ? -23.237 -21.194 43.379 1.00 44.77 ? 428 ARG A NE 1 ATOM 3276 C CZ . ARG A 1 428 ? -23.697 -22.419 43.093 1.00 48.47 ? 428 ARG A CZ 1 ATOM 3277 N NH1 . ARG A 1 428 ? -23.837 -22.804 41.818 1.00 48.87 ? 428 ARG A NH1 1 ATOM 3278 N NH2 . ARG A 1 428 ? -24.049 -23.250 44.084 1.00 48.37 ? 428 ARG A NH2 1 ATOM 3279 N N . GLY A 1 429 ? -20.784 -16.442 41.086 1.00 23.28 ? 429 GLY A N 1 ATOM 3280 C CA . GLY A 1 429 ? -19.405 -16.215 41.561 1.00 21.90 ? 429 GLY A CA 1 ATOM 3281 C C . GLY A 1 429 ? -19.117 -14.753 41.960 1.00 21.68 ? 429 GLY A C 1 ATOM 3282 O O . GLY A 1 429 ? -18.153 -14.446 42.710 1.00 22.51 ? 429 GLY A O 1 ATOM 3283 N N . LEU A 1 430 ? -19.952 -13.838 41.488 1.00 19.71 ? 430 LEU A N 1 ATOM 3284 C CA . LEU A 1 430 ? -19.712 -12.414 41.730 1.00 18.19 ? 430 LEU A CA 1 ATOM 3285 C C . LEU A 1 430 ? -20.468 -11.913 42.948 1.00 18.03 ? 430 LEU A C 1 ATOM 3286 O O . LEU A 1 430 ? -21.039 -10.783 42.949 1.00 17.74 ? 430 LEU A O 1 ATOM 3287 C CB . LEU A 1 430 ? -20.043 -11.585 40.479 1.00 17.54 ? 430 LEU A CB 1 ATOM 3288 C CG . LEU A 1 430 ? -19.364 -11.858 39.121 1.00 14.85 ? 430 LEU A CG 1 ATOM 3289 C CD1 . LEU A 1 430 ? -20.047 -10.973 38.088 1.00 14.70 ? 430 LEU A CD1 1 ATOM 3290 C CD2 . LEU A 1 430 ? -17.829 -11.620 39.127 1.00 9.64 ? 430 LEU A CD2 1 ATOM 3291 N N . SER A 1 431 ? -20.470 -12.771 43.979 1.00 18.01 ? 431 SER A N 1 ATOM 3292 C CA . SER A 1 431 ? -21.051 -12.473 45.291 1.00 18.36 ? 431 SER A CA 1 ATOM 3293 C C . SER A 1 431 ? -20.402 -11.266 45.932 1.00 18.53 ? 431 SER A C 1 ATOM 3294 O O . SER A 1 431 ? -21.076 -10.515 46.640 1.00 18.57 ? 431 SER A O 1 ATOM 3295 C CB . SER A 1 431 ? -20.884 -13.667 46.229 1.00 18.74 ? 431 SER A CB 1 ATOM 3296 O OG . SER A 1 431 ? -19.634 -14.273 46.007 1.00 17.82 ? 431 SER A OG 1 ATOM 3297 N N . PHE A 1 432 ? -19.100 -11.066 45.682 1.00 18.78 ? 432 PHE A N 1 ATOM 3298 C CA . PHE A 1 432 ? -18.441 -9.871 46.184 1.00 19.05 ? 432 PHE A CA 1 ATOM 3299 C C . PHE A 1 432 ? -19.224 -8.659 45.683 1.00 19.80 ? 432 PHE A C 1 ATOM 3300 O O . PHE A 1 432 ? -19.795 -7.935 46.485 1.00 20.15 ? 432 PHE A O 1 ATOM 3301 C CB . PHE A 1 432 ? -16.964 -9.831 45.802 1.00 19.62 ? 432 PHE A CB 1 ATOM 3302 C CG . PHE A 1 432 ? -16.255 -8.520 46.178 1.00 20.18 ? 432 PHE A CG 1 ATOM 3303 C CD1 . PHE A 1 432 ? -15.831 -8.282 47.490 1.00 18.92 ? 432 PHE A CD1 1 ATOM 3304 C CD2 . PHE A 1 432 ? -16.019 -7.550 45.215 1.00 19.69 ? 432 PHE A CD2 1 ATOM 3305 C CE1 . PHE A 1 432 ? -15.218 -7.124 47.822 1.00 18.45 ? 432 PHE A CE1 1 ATOM 3306 C CE2 . PHE A 1 432 ? -15.386 -6.371 45.542 1.00 20.79 ? 432 PHE A CE2 1 ATOM 3307 C CZ . PHE A 1 432 ? -15.013 -6.133 46.856 1.00 20.03 ? 432 PHE A CZ 1 ATOM 3308 N N . ALA A 1 433 ? -19.334 -8.473 44.365 1.00 19.64 ? 433 ALA A N 1 ATOM 3309 C CA . ALA A 1 433 ? -20.084 -7.310 43.842 1.00 19.02 ? 433 ALA A CA 1 ATOM 3310 C C . ALA A 1 433 ? -21.573 -7.352 44.230 1.00 19.45 ? 433 ALA A C 1 ATOM 3311 O O . ALA A 1 433 ? -22.224 -6.309 44.484 1.00 17.51 ? 433 ALA A O 1 ATOM 3312 C CB . ALA A 1 433 ? -19.898 -7.191 42.338 1.00 17.86 ? 433 ALA A CB 1 ATOM 3313 N N . ARG A 1 434 ? -22.101 -8.572 44.309 1.00 20.81 ? 434 ARG A N 1 ATOM 3314 C CA . ARG A 1 434 ? -23.554 -8.726 44.510 1.00 22.39 ? 434 ARG A CA 1 ATOM 3315 C C . ARG A 1 434 ? -23.950 -8.279 45.904 1.00 22.57 ? 434 ARG A C 1 ATOM 3316 O O . ARG A 1 434 ? -25.090 -7.821 46.112 1.00 22.87 ? 434 ARG A O 1 ATOM 3317 C CB . ARG A 1 434 ? -24.081 -10.156 44.215 1.00 21.82 ? 434 ARG A CB 1 ATOM 3318 C CG . ARG A 1 434 ? -24.533 -10.394 42.777 1.00 24.26 ? 434 ARG A CG 1 ATOM 3319 C CD . ARG A 1 434 ? -25.230 -11.815 42.478 1.00 25.48 ? 434 ARG A CD 1 ATOM 3320 N NE . ARG A 1 434 ? -24.486 -12.989 42.972 1.00 29.00 ? 434 ARG A NE 1 ATOM 3321 C CZ . ARG A 1 434 ? -24.748 -13.594 44.133 1.00 28.11 ? 434 ARG A CZ 1 ATOM 3322 N NH1 . ARG A 1 434 ? -25.733 -13.134 44.898 1.00 28.46 ? 434 ARG A NH1 1 ATOM 3323 N NH2 . ARG A 1 434 ? -24.034 -14.643 44.539 1.00 25.96 ? 434 ARG A NH2 1 ATOM 3324 N N . SER A 1 435 ? -23.013 -8.402 46.848 1.00 22.96 ? 435 SER A N 1 ATOM 3325 C CA . SER A 1 435 ? -23.255 -8.025 48.254 1.00 23.08 ? 435 SER A CA 1 ATOM 3326 C C . SER A 1 435 ? -22.970 -6.543 48.493 1.00 23.01 ? 435 SER A C 1 ATOM 3327 O O . SER A 1 435 ? -23.282 -5.997 49.548 1.00 23.60 ? 435 SER A O 1 ATOM 3328 C CB . SER A 1 435 ? -22.494 -8.946 49.237 1.00 23.13 ? 435 SER A CB 1 ATOM 3329 O OG . SER A 1 435 ? -21.103 -9.121 48.889 1.00 23.96 ? 435 SER A OG 1 ATOM 3330 N N . GLY A 1 436 ? -22.440 -5.874 47.484 1.00 22.66 ? 436 GLY A N 1 ATOM 3331 C CA . GLY A 1 436 ? -22.037 -4.476 47.636 1.00 22.73 ? 436 GLY A CA 1 ATOM 3332 C C . GLY A 1 436 ? -20.540 -4.284 47.922 1.00 22.28 ? 436 GLY A C 1 ATOM 3333 O O . GLY A 1 436 ? -20.102 -3.178 48.233 1.00 21.70 ? 436 GLY A O 1 ATOM 3334 N N . GLY A 1 437 ? -19.758 -5.359 47.821 1.00 22.06 ? 437 GLY A N 1 ATOM 3335 C CA . GLY A 1 437 ? -18.328 -5.342 48.169 1.00 22.89 ? 437 GLY A CA 1 ATOM 3336 C C . GLY A 1 437 ? -18.069 -4.686 49.524 1.00 23.10 ? 437 GLY A C 1 ATOM 3337 O O . GLY A 1 437 ? -18.793 -4.951 50.484 1.00 24.41 ? 437 GLY A O 1 ATOM 3338 N N . ASP A 1 438 ? -17.070 -3.806 49.605 1.00 22.57 ? 438 ASP A N 1 ATOM 3339 C CA . ASP A 1 438 ? -16.792 -3.082 50.845 1.00 22.74 ? 438 ASP A CA 1 ATOM 3340 C C . ASP A 1 438 ? -17.253 -1.647 50.764 1.00 23.34 ? 438 ASP A C 1 ATOM 3341 O O . ASP A 1 438 ? -16.652 -0.763 51.380 1.00 23.76 ? 438 ASP A O 1 ATOM 3342 C CB . ASP A 1 438 ? -15.311 -3.153 51.229 1.00 21.39 ? 438 ASP A CB 1 ATOM 3343 C CG . ASP A 1 438 ? -14.811 -4.571 51.272 1.00 21.72 ? 438 ASP A CG 1 ATOM 3344 O OD1 . ASP A 1 438 ? -15.491 -5.427 51.869 1.00 23.18 ? 438 ASP A OD1 1 ATOM 3345 O OD2 . ASP A 1 438 ? -13.749 -4.860 50.698 1.00 21.47 ? 438 ASP A OD2 1 ATOM 3346 N N . TRP A 1 439 ? -18.331 -1.400 50.031 1.00 23.67 ? 439 TRP A N 1 ATOM 3347 C CA . TRP A 1 439 ? -18.743 -0.032 49.824 1.00 23.69 ? 439 TRP A CA 1 ATOM 3348 C C . TRP A 1 439 ? -19.076 0.638 51.177 1.00 25.03 ? 439 TRP A C 1 ATOM 3349 O O . TRP A 1 439 ? -18.850 1.856 51.345 1.00 24.39 ? 439 TRP A O 1 ATOM 3350 C CB . TRP A 1 439 ? -19.893 0.053 48.817 1.00 22.22 ? 439 TRP A CB 1 ATOM 3351 C CG . TRP A 1 439 ? -20.200 1.445 48.421 1.00 20.60 ? 439 TRP A CG 1 ATOM 3352 C CD1 . TRP A 1 439 ? -21.147 2.277 48.979 1.00 18.39 ? 439 TRP A CD1 1 ATOM 3353 C CD2 . TRP A 1 439 ? -19.523 2.221 47.417 1.00 19.27 ? 439 TRP A CD2 1 ATOM 3354 N NE1 . TRP A 1 439 ? -21.109 3.505 48.366 1.00 19.70 ? 439 TRP A NE1 1 ATOM 3355 C CE2 . TRP A 1 439 ? -20.120 3.500 47.408 1.00 18.40 ? 439 TRP A CE2 1 ATOM 3356 C CE3 . TRP A 1 439 ? -18.484 1.950 46.505 1.00 18.44 ? 439 TRP A CE3 1 ATOM 3357 C CZ2 . TRP A 1 439 ? -19.725 4.490 46.529 1.00 18.47 ? 439 TRP A CZ2 1 ATOM 3358 C CZ3 . TRP A 1 439 ? -18.091 2.951 45.611 1.00 17.95 ? 439 TRP A CZ3 1 ATOM 3359 C CH2 . TRP A 1 439 ? -18.711 4.204 45.632 1.00 18.57 ? 439 TRP A CH2 1 ATOM 3360 N N . ALA A 1 440 ? -19.587 -0.151 52.142 1.00 26.75 ? 440 ALA A N 1 ATOM 3361 C CA . ALA A 1 440 ? -19.927 0.391 53.489 1.00 28.46 ? 440 ALA A CA 1 ATOM 3362 C C . ALA A 1 440 ? -18.725 1.044 54.207 1.00 29.57 ? 440 ALA A C 1 ATOM 3363 O O . ALA A 1 440 ? -18.890 1.893 55.071 1.00 29.87 ? 440 ALA A O 1 ATOM 3364 C CB . ALA A 1 440 ? -20.574 -0.693 54.381 1.00 27.94 ? 440 ALA A CB 1 ATOM 3365 N N . GLU A 1 441 ? -17.517 0.643 53.818 1.00 31.28 ? 441 GLU A N 1 ATOM 3366 C CA . GLU A 1 441 ? -16.299 1.144 54.415 1.00 32.90 ? 441 GLU A CA 1 ATOM 3367 C C . GLU A 1 441 ? -15.848 2.465 53.823 1.00 33.20 ? 441 GLU A C 1 ATOM 3368 O O . GLU A 1 441 ? -14.807 2.987 54.203 1.00 33.42 ? 441 GLU A O 1 ATOM 3369 C CB . GLU A 1 441 ? -15.211 0.084 54.307 1.00 33.64 ? 441 GLU A CB 1 ATOM 3370 C CG . GLU A 1 441 ? -15.619 -1.204 55.036 1.00 37.35 ? 441 GLU A CG 1 ATOM 3371 C CD . GLU A 1 441 ? -14.482 -2.214 55.195 1.00 42.48 ? 441 GLU A CD 1 ATOM 3372 O OE1 . GLU A 1 441 ? -13.305 -1.837 54.990 1.00 43.93 ? 441 GLU A OE1 1 ATOM 3373 O OE2 . GLU A 1 441 ? -14.781 -3.387 55.551 1.00 43.73 ? 441 GLU A OE2 1 ATOM 3374 N N . CYS A 1 442 ? -16.642 3.021 52.910 1.00 33.78 ? 442 CYS A N 1 ATOM 3375 C CA . CYS A 1 442 ? -16.284 4.262 52.227 1.00 33.87 ? 442 CYS A CA 1 ATOM 3376 C C . CYS A 1 442 ? -16.433 5.437 53.174 1.00 35.68 ? 442 CYS A C 1 ATOM 3377 O O . CYS A 1 442 ? -15.924 6.531 52.913 1.00 35.40 ? 442 CYS A O 1 ATOM 3378 C CB . CYS A 1 442 ? -17.143 4.475 50.974 1.00 33.25 ? 442 CYS A CB 1 ATOM 3379 S SG . CYS A 1 442 ? -16.781 3.410 49.506 1.00 30.08 ? 442 CYS A SG 1 ATOM 3380 N N . PHE A 1 443 ? -17.117 5.198 54.292 1.00 38.00 ? 443 PHE A N 1 ATOM 3381 C CA . PHE A 1 443 ? -17.596 6.283 55.161 1.00 40.40 ? 443 PHE A CA 1 ATOM 3382 C C . PHE A 1 443 ? -17.131 6.217 56.626 1.00 41.97 ? 443 PHE A C 1 ATOM 3383 O O . PHE A 1 443 ? -16.777 7.237 57.201 1.00 42.48 ? 443 PHE A O 1 ATOM 3384 C CB . PHE A 1 443 ? -19.117 6.403 55.011 1.00 40.42 ? 443 PHE A CB 1 ATOM 3385 C CG . PHE A 1 443 ? -19.546 6.498 53.583 1.00 40.02 ? 443 PHE A CG 1 ATOM 3386 C CD1 . PHE A 1 443 ? -19.313 7.666 52.862 1.00 39.53 ? 443 PHE A CD1 1 ATOM 3387 C CD2 . PHE A 1 443 ? -20.093 5.394 52.928 1.00 40.73 ? 443 PHE A CD2 1 ATOM 3388 C CE1 . PHE A 1 443 ? -19.655 7.765 51.532 1.00 39.10 ? 443 PHE A CE1 1 ATOM 3389 C CE2 . PHE A 1 443 ? -20.463 5.485 51.578 1.00 41.45 ? 443 PHE A CE2 1 ATOM 3390 C CZ . PHE A 1 443 ? -20.239 6.684 50.884 1.00 41.17 ? 443 PHE A CZ 1 ATOM 3391 N N . ALA A 1 444 ? -17.118 5.025 57.215 1.00 44.15 ? 444 ALA A N 1 ATOM 3392 C CA . ALA A 1 444 ? -16.440 4.800 58.508 1.00 46.25 ? 444 ALA A CA 1 ATOM 3393 C C . ALA A 1 444 ? -14.928 4.440 58.353 1.00 47.24 ? 444 ALA A C 1 ATOM 3394 O O . ALA A 1 444 ? -14.038 5.322 58.420 1.00 47.76 ? 444 ALA A O 1 ATOM 3395 C CB . ALA A 1 444 ? -17.196 3.709 59.349 1.00 46.78 ? 444 ALA A CB 1 ATOM 3396 O OXT . ALA A 1 444 ? -14.553 3.260 58.166 1.00 47.38 ? 444 ALA A OXT 1 ATOM 3397 N N . SER B 1 7 ? 1.683 -19.579 -1.389 1.00 43.03 ? 7 SER B N 1 ATOM 3398 C CA . SER B 1 7 ? 1.339 -18.124 -1.606 1.00 43.23 ? 7 SER B CA 1 ATOM 3399 C C . SER B 1 7 ? 1.953 -17.140 -0.577 1.00 42.92 ? 7 SER B C 1 ATOM 3400 O O . SER B 1 7 ? 1.771 -15.910 -0.716 1.00 43.13 ? 7 SER B O 1 ATOM 3401 C CB . SER B 1 7 ? -0.179 -17.919 -1.666 1.00 43.93 ? 7 SER B CB 1 ATOM 3402 O OG . SER B 1 7 ? -0.797 -18.706 -2.698 1.00 45.77 ? 7 SER B OG 1 ATOM 3403 N N . CYS B 1 8 ? 2.616 -17.690 0.462 1.00 41.76 ? 8 CYS B N 1 ATOM 3404 C CA . CYS B 1 8 ? 3.620 -16.976 1.313 1.00 40.63 ? 8 CYS B CA 1 ATOM 3405 C C . CYS B 1 8 ? 5.023 -17.519 0.922 1.00 39.46 ? 8 CYS B C 1 ATOM 3406 O O . CYS B 1 8 ? 6.067 -17.084 1.409 1.00 39.31 ? 8 CYS B O 1 ATOM 3407 C CB . CYS B 1 8 ? 3.341 -17.145 2.828 1.00 40.10 ? 8 CYS B CB 1 ATOM 3408 S SG . CYS B 1 8 ? 2.958 -18.885 3.382 1.00 41.29 ? 8 CYS B SG 1 ATOM 3409 N N . ASP B 1 9 ? 5.005 -18.467 0.002 1.00 37.78 ? 9 ASP B N 1 ATOM 3410 C CA . ASP B 1 9 ? 6.189 -19.010 -0.596 1.00 36.83 ? 9 ASP B CA 1 ATOM 3411 C C . ASP B 1 9 ? 6.176 -18.758 -2.109 1.00 36.29 ? 9 ASP B C 1 ATOM 3412 O O . ASP B 1 9 ? 5.562 -19.530 -2.875 1.00 36.93 ? 9 ASP B O 1 ATOM 3413 C CB . ASP B 1 9 ? 6.241 -20.514 -0.342 1.00 36.58 ? 9 ASP B CB 1 ATOM 3414 C CG . ASP B 1 9 ? 7.576 -21.127 -0.725 1.00 36.49 ? 9 ASP B CG 1 ATOM 3415 O OD1 . ASP B 1 9 ? 8.600 -20.417 -0.778 1.00 37.34 ? 9 ASP B OD1 1 ATOM 3416 O OD2 . ASP B 1 9 ? 7.608 -22.335 -0.962 1.00 37.14 ? 9 ASP B OD2 1 ATOM 3417 N N . THR B 1 10 ? 6.877 -17.706 -2.533 1.00 34.41 ? 10 THR B N 1 ATOM 3418 C CA . THR B 1 10 ? 6.887 -17.262 -3.924 1.00 33.12 ? 10 THR B CA 1 ATOM 3419 C C . THR B 1 10 ? 8.277 -17.345 -4.555 1.00 32.76 ? 10 THR B C 1 ATOM 3420 O O . THR B 1 10 ? 9.306 -17.515 -3.866 1.00 32.09 ? 10 THR B O 1 ATOM 3421 C CB . THR B 1 10 ? 6.419 -15.807 -4.037 1.00 32.99 ? 10 THR B CB 1 ATOM 3422 O OG1 . THR B 1 10 ? 7.235 -14.967 -3.205 1.00 33.40 ? 10 THR B OG1 1 ATOM 3423 C CG2 . THR B 1 10 ? 4.947 -15.662 -3.601 1.00 32.63 ? 10 THR B CG2 1 ATOM 3424 N N . VAL B 1 11 ? 8.306 -17.213 -5.872 1.00 32.06 ? 11 VAL B N 1 ATOM 3425 C CA . VAL B 1 11 ? 9.571 -17.225 -6.599 1.00 32.23 ? 11 VAL B CA 1 ATOM 3426 C C . VAL B 1 11 ? 10.378 -15.998 -6.217 1.00 31.78 ? 11 VAL B C 1 ATOM 3427 O O . VAL B 1 11 ? 11.600 -16.042 -6.103 1.00 31.09 ? 11 VAL B O 1 ATOM 3428 C CB . VAL B 1 11 ? 9.356 -17.266 -8.151 1.00 32.36 ? 11 VAL B CB 1 ATOM 3429 C CG1 . VAL B 1 11 ? 10.640 -16.928 -8.896 1.00 31.69 ? 11 VAL B CG1 1 ATOM 3430 C CG2 . VAL B 1 11 ? 8.810 -18.634 -8.588 1.00 32.36 ? 11 VAL B CG2 1 ATOM 3431 N N . ASP B 1 12 ? 9.679 -14.895 -5.998 1.00 32.12 ? 12 ASP B N 1 ATOM 3432 C CA . ASP B 1 12 ? 10.393 -13.654 -5.854 1.00 32.23 ? 12 ASP B CA 1 ATOM 3433 C C . ASP B 1 12 ? 10.836 -13.370 -4.423 1.00 31.37 ? 12 ASP B C 1 ATOM 3434 O O . ASP B 1 12 ? 11.956 -12.902 -4.202 1.00 30.70 ? 12 ASP B O 1 ATOM 3435 C CB . ASP B 1 12 ? 9.591 -12.499 -6.428 1.00 33.11 ? 12 ASP B CB 1 ATOM 3436 C CG . ASP B 1 12 ? 10.431 -11.651 -7.361 1.00 36.40 ? 12 ASP B CG 1 ATOM 3437 O OD1 . ASP B 1 12 ? 11.192 -10.755 -6.858 1.00 33.03 ? 12 ASP B OD1 1 ATOM 3438 O OD2 . ASP B 1 12 ? 10.323 -11.924 -8.595 1.00 39.81 ? 12 ASP B OD2 1 ATOM 3439 N N . GLN B 1 13 ? 9.962 -13.649 -3.462 1.00 30.12 ? 13 GLN B N 1 ATOM 3440 C CA . GLN B 1 13 ? 10.255 -13.282 -2.098 1.00 29.49 ? 13 GLN B CA 1 ATOM 3441 C C . GLN B 1 13 ? 10.749 -14.455 -1.274 1.00 28.99 ? 13 GLN B C 1 ATOM 3442 O O . GLN B 1 13 ? 11.240 -14.251 -0.177 1.00 28.71 ? 13 GLN B O 1 ATOM 3443 C CB . GLN B 1 13 ? 9.070 -12.568 -1.450 1.00 29.72 ? 13 GLN B CB 1 ATOM 3444 C CG . GLN B 1 13 ? 8.888 -11.127 -1.923 1.00 31.48 ? 13 GLN B CG 1 ATOM 3445 C CD . GLN B 1 13 ? 9.986 -10.182 -1.425 1.00 35.53 ? 13 GLN B CD 1 ATOM 3446 O OE1 . GLN B 1 13 ? 10.054 -9.849 -0.229 1.00 37.79 ? 13 GLN B OE1 1 ATOM 3447 N NE2 . GLN B 1 13 ? 10.833 -9.723 -2.345 1.00 35.45 ? 13 GLN B NE2 1 ATOM 3448 N N . GLY B 1 14 ? 10.662 -15.674 -1.827 1.00 28.41 ? 14 GLY B N 1 ATOM 3449 C CA . GLY B 1 14 ? 11.161 -16.873 -1.167 1.00 27.85 ? 14 GLY B CA 1 ATOM 3450 C C . GLY B 1 14 ? 10.195 -17.358 -0.091 1.00 28.26 ? 14 GLY B C 1 ATOM 3451 O O . GLY B 1 14 ? 8.986 -17.241 -0.240 1.00 28.12 ? 14 GLY B O 1 ATOM 3452 N N . TYR B 1 15 ? 10.723 -17.887 1.012 1.00 27.85 ? 15 TYR B N 1 ATOM 3453 C CA . TYR B 1 15 ? 9.869 -18.539 1.973 1.00 28.58 ? 15 TYR B CA 1 ATOM 3454 C C . TYR B 1 15 ? 9.479 -17.601 3.100 1.00 29.13 ? 15 TYR B C 1 ATOM 3455 O O . TYR B 1 15 ? 10.251 -17.386 4.035 1.00 29.48 ? 15 TYR B O 1 ATOM 3456 C CB . TYR B 1 15 ? 10.534 -19.795 2.482 1.00 27.95 ? 15 TYR B CB 1 ATOM 3457 C CG . TYR B 1 15 ? 9.676 -20.633 3.390 1.00 29.03 ? 15 TYR B CG 1 ATOM 3458 C CD1 . TYR B 1 15 ? 8.919 -21.673 2.888 1.00 29.16 ? 15 TYR B CD1 1 ATOM 3459 C CD2 . TYR B 1 15 ? 9.637 -20.393 4.759 1.00 28.02 ? 15 TYR B CD2 1 ATOM 3460 C CE1 . TYR B 1 15 ? 8.144 -22.455 3.723 1.00 28.73 ? 15 TYR B CE1 1 ATOM 3461 C CE2 . TYR B 1 15 ? 8.888 -21.158 5.591 1.00 27.52 ? 15 TYR B CE2 1 ATOM 3462 C CZ . TYR B 1 15 ? 8.143 -22.188 5.082 1.00 28.31 ? 15 TYR B CZ 1 ATOM 3463 O OH . TYR B 1 15 ? 7.371 -22.949 5.925 1.00 27.32 ? 15 TYR B OH 1 ATOM 3464 N N . GLN B 1 16 ? 8.286 -17.017 2.992 1.00 30.02 ? 16 GLN B N 1 ATOM 3465 C CA . GLN B 1 16 ? 7.828 -15.990 3.964 1.00 30.98 ? 16 GLN B CA 1 ATOM 3466 C C . GLN B 1 16 ? 6.694 -16.519 4.839 1.00 32.02 ? 16 GLN B C 1 ATOM 3467 O O . GLN B 1 16 ? 6.052 -15.757 5.558 1.00 33.38 ? 16 GLN B O 1 ATOM 3468 C CB . GLN B 1 16 ? 7.399 -14.669 3.279 1.00 30.08 ? 16 GLN B CB 1 ATOM 3469 C CG . GLN B 1 16 ? 8.412 -14.040 2.347 1.00 29.41 ? 16 GLN B CG 1 ATOM 3470 C CD . GLN B 1 16 ? 9.533 -13.304 3.074 1.00 31.64 ? 16 GLN B CD 1 ATOM 3471 O OE1 . GLN B 1 16 ? 9.400 -12.971 4.265 1.00 28.49 ? 16 GLN B OE1 1 ATOM 3472 N NE2 . GLN B 1 16 ? 10.652 -13.017 2.346 1.00 30.01 ? 16 GLN B NE2 1 ATOM 3473 N N . CYS B 1 17 ? 6.419 -17.815 4.753 1.00 33.11 ? 17 CYS B N 1 ATOM 3474 C CA . CYS B 1 17 ? 5.506 -18.463 5.682 1.00 33.86 ? 17 CYS B CA 1 ATOM 3475 C C . CYS B 1 17 ? 6.176 -18.546 7.058 1.00 33.91 ? 17 CYS B C 1 ATOM 3476 O O . CYS B 1 17 ? 7.386 -18.842 7.132 1.00 34.55 ? 17 CYS B O 1 ATOM 3477 C CB . CYS B 1 17 ? 5.193 -19.862 5.181 1.00 33.99 ? 17 CYS B CB 1 ATOM 3478 S SG . CYS B 1 17 ? 4.758 -19.898 3.435 1.00 38.07 ? 17 CYS B SG 1 ATOM 3479 N N . PHE B 1 18 ? 5.416 -18.264 8.124 1.00 32.89 ? 18 PHE B N 1 ATOM 3480 C CA . PHE B 1 18 ? 5.841 -18.520 9.507 1.00 32.32 ? 18 PHE B CA 1 ATOM 3481 C C . PHE B 1 18 ? 7.133 -17.815 9.896 1.00 32.09 ? 18 PHE B C 1 ATOM 3482 O O . PHE B 1 18 ? 7.941 -18.336 10.679 1.00 32.48 ? 18 PHE B O 1 ATOM 3483 C CB . PHE B 1 18 ? 6.008 -20.022 9.711 1.00 31.98 ? 18 PHE B CB 1 ATOM 3484 C CG . PHE B 1 18 ? 4.858 -20.810 9.228 1.00 32.03 ? 18 PHE B CG 1 ATOM 3485 C CD1 . PHE B 1 18 ? 3.571 -20.580 9.742 1.00 31.47 ? 18 PHE B CD1 1 ATOM 3486 C CD2 . PHE B 1 18 ? 5.040 -21.793 8.265 1.00 30.73 ? 18 PHE B CD2 1 ATOM 3487 C CE1 . PHE B 1 18 ? 2.493 -21.325 9.287 1.00 30.69 ? 18 PHE B CE1 1 ATOM 3488 C CE2 . PHE B 1 18 ? 3.979 -22.549 7.811 1.00 29.54 ? 18 PHE B CE2 1 ATOM 3489 C CZ . PHE B 1 18 ? 2.689 -22.316 8.321 1.00 29.44 ? 18 PHE B CZ 1 ATOM 3490 N N . SER B 1 19 ? 7.294 -16.612 9.369 1.00 31.95 ? 19 SER B N 1 ATOM 3491 C CA . SER B 1 19 ? 8.574 -15.941 9.286 1.00 31.62 ? 19 SER B CA 1 ATOM 3492 C C . SER B 1 19 ? 9.195 -15.660 10.663 1.00 30.80 ? 19 SER B C 1 ATOM 3493 O O . SER B 1 19 ? 10.426 -15.581 10.787 1.00 30.49 ? 19 SER B O 1 ATOM 3494 C CB . SER B 1 19 ? 8.386 -14.644 8.509 1.00 32.07 ? 19 SER B CB 1 ATOM 3495 O OG . SER B 1 19 ? 7.626 -13.748 9.315 1.00 34.05 ? 19 SER B OG 1 ATOM 3496 N N . GLU B 1 20 ? 8.350 -15.516 11.688 1.00 29.74 ? 20 GLU B N 1 ATOM 3497 C CA . GLU B 1 20 ? 8.832 -15.244 13.060 1.00 29.38 ? 20 GLU B CA 1 ATOM 3498 C C . GLU B 1 20 ? 9.618 -16.435 13.680 1.00 27.73 ? 20 GLU B C 1 ATOM 3499 O O . GLU B 1 20 ? 10.393 -16.259 14.602 1.00 27.26 ? 20 GLU B O 1 ATOM 3500 C CB . GLU B 1 20 ? 7.697 -14.714 13.990 1.00 29.73 ? 20 GLU B CB 1 ATOM 3501 C CG . GLU B 1 20 ? 6.635 -15.741 14.397 1.00 32.64 ? 20 GLU B CG 1 ATOM 3502 C CD . GLU B 1 20 ? 5.775 -16.292 13.205 1.00 39.32 ? 20 GLU B CD 1 ATOM 3503 O OE1 . GLU B 1 20 ? 5.352 -15.497 12.300 1.00 37.02 ? 20 GLU B OE1 1 ATOM 3504 O OE2 . GLU B 1 20 ? 5.511 -17.545 13.201 1.00 42.18 ? 20 GLU B OE2 1 ATOM 3505 N N . THR B 1 21 ? 9.402 -17.628 13.139 1.00 26.19 ? 21 THR B N 1 ATOM 3506 C CA . THR B 1 21 ? 10.136 -18.829 13.505 1.00 25.40 ? 21 THR B CA 1 ATOM 3507 C C . THR B 1 21 ? 11.092 -19.260 12.371 1.00 25.78 ? 21 THR B C 1 ATOM 3508 O O . THR B 1 21 ? 12.302 -19.463 12.595 1.00 25.17 ? 21 THR B O 1 ATOM 3509 C CB . THR B 1 21 ? 9.123 -19.945 13.782 1.00 24.67 ? 21 THR B CB 1 ATOM 3510 O OG1 . THR B 1 21 ? 8.409 -19.566 14.948 1.00 27.40 ? 21 THR B OG1 1 ATOM 3511 C CG2 . THR B 1 21 ? 9.756 -21.263 14.032 1.00 22.98 ? 21 THR B CG2 1 ATOM 3512 N N . SER B 1 22 ? 10.547 -19.369 11.154 1.00 25.42 ? 22 SER B N 1 ATOM 3513 C CA . SER B 1 22 ? 11.262 -20.025 10.053 1.00 26.25 ? 22 SER B CA 1 ATOM 3514 C C . SER B 1 22 ? 12.523 -19.260 9.641 1.00 26.75 ? 22 SER B C 1 ATOM 3515 O O . SER B 1 22 ? 13.434 -19.837 9.017 1.00 27.75 ? 22 SER B O 1 ATOM 3516 C CB . SER B 1 22 ? 10.355 -20.216 8.847 1.00 25.97 ? 22 SER B CB 1 ATOM 3517 O OG . SER B 1 22 ? 10.077 -18.951 8.248 1.00 25.79 ? 22 SER B OG 1 ATOM 3518 N N . HIS B 1 23 ? 12.578 -17.976 9.996 1.00 26.10 ? 23 HIS B N 1 ATOM 3519 C CA . HIS B 1 23 ? 13.703 -17.105 9.616 1.00 25.57 ? 23 HIS B CA 1 ATOM 3520 C C . HIS B 1 23 ? 14.876 -17.167 10.616 1.00 24.96 ? 23 HIS B C 1 ATOM 3521 O O . HIS B 1 23 ? 15.963 -16.649 10.339 1.00 24.64 ? 23 HIS B O 1 ATOM 3522 C CB . HIS B 1 23 ? 13.209 -15.669 9.404 1.00 24.76 ? 23 HIS B CB 1 ATOM 3523 C CG . HIS B 1 23 ? 12.401 -15.484 8.146 1.00 27.98 ? 23 HIS B CG 1 ATOM 3524 N ND1 . HIS B 1 23 ? 12.127 -14.240 7.603 1.00 31.81 ? 23 HIS B ND1 1 ATOM 3525 C CD2 . HIS B 1 23 ? 11.824 -16.386 7.312 1.00 28.25 ? 23 HIS B CD2 1 ATOM 3526 C CE1 . HIS B 1 23 ? 11.428 -14.388 6.488 1.00 29.91 ? 23 HIS B CE1 1 ATOM 3527 N NE2 . HIS B 1 23 ? 11.235 -15.680 6.286 1.00 27.60 ? 23 HIS B NE2 1 ATOM 3528 N N . LEU B 1 24 ? 14.658 -17.821 11.756 1.00 24.62 ? 24 LEU B N 1 ATOM 3529 C CA . LEU B 1 24 ? 15.699 -17.938 12.798 1.00 24.24 ? 24 LEU B CA 1 ATOM 3530 C C . LEU B 1 24 ? 16.287 -19.349 12.880 1.00 23.41 ? 24 LEU B C 1 ATOM 3531 O O . LEU B 1 24 ? 16.814 -19.735 13.923 1.00 22.97 ? 24 LEU B O 1 ATOM 3532 C CB . LEU B 1 24 ? 15.198 -17.484 14.172 1.00 24.12 ? 24 LEU B CB 1 ATOM 3533 C CG . LEU B 1 24 ? 14.653 -16.045 14.181 1.00 25.56 ? 24 LEU B CG 1 ATOM 3534 C CD1 . LEU B 1 24 ? 13.666 -15.793 15.345 1.00 26.30 ? 24 LEU B CD1 1 ATOM 3535 C CD2 . LEU B 1 24 ? 15.777 -14.993 14.142 1.00 23.70 ? 24 LEU B CD2 1 ATOM 3536 N N . TRP B 1 25 ? 16.208 -20.104 11.779 1.00 21.73 ? 25 TRP B N 1 ATOM 3537 C CA . TRP B 1 25 ? 16.836 -21.408 11.737 1.00 21.03 ? 25 TRP B CA 1 ATOM 3538 C C . TRP B 1 25 ? 18.317 -21.330 11.252 1.00 19.59 ? 25 TRP B C 1 ATOM 3539 O O . TRP B 1 25 ? 18.922 -22.326 10.933 1.00 18.57 ? 25 TRP B O 1 ATOM 3540 C CB . TRP B 1 25 ? 16.000 -22.383 10.901 1.00 21.04 ? 25 TRP B CB 1 ATOM 3541 C CG . TRP B 1 25 ? 14.620 -22.633 11.467 1.00 23.45 ? 25 TRP B CG 1 ATOM 3542 C CD1 . TRP B 1 25 ? 14.249 -22.551 12.767 1.00 23.57 ? 25 TRP B CD1 1 ATOM 3543 C CD2 . TRP B 1 25 ? 13.429 -23.020 10.739 1.00 24.64 ? 25 TRP B CD2 1 ATOM 3544 N NE1 . TRP B 1 25 ? 12.911 -22.858 12.910 1.00 23.80 ? 25 TRP B NE1 1 ATOM 3545 C CE2 . TRP B 1 25 ? 12.384 -23.146 11.683 1.00 24.98 ? 25 TRP B CE2 1 ATOM 3546 C CE3 . TRP B 1 25 ? 13.152 -23.275 9.390 1.00 23.80 ? 25 TRP B CE3 1 ATOM 3547 C CZ2 . TRP B 1 25 ? 11.074 -23.515 11.322 1.00 25.16 ? 25 TRP B CZ2 1 ATOM 3548 C CZ3 . TRP B 1 25 ? 11.855 -23.645 9.025 1.00 25.06 ? 25 TRP B CZ3 1 ATOM 3549 C CH2 . TRP B 1 25 ? 10.827 -23.763 9.998 1.00 24.79 ? 25 TRP B CH2 1 ATOM 3550 N N . GLY B 1 26 ? 18.895 -20.146 11.221 1.00 18.93 ? 26 GLY B N 1 ATOM 3551 C CA . GLY B 1 26 ? 20.220 -19.980 10.587 1.00 19.36 ? 26 GLY B CA 1 ATOM 3552 C C . GLY B 1 26 ? 20.344 -20.577 9.204 1.00 18.90 ? 26 GLY B C 1 ATOM 3553 O O . GLY B 1 26 ? 19.624 -20.183 8.292 1.00 19.78 ? 26 GLY B O 1 ATOM 3554 N N . GLN B 1 27 ? 21.269 -21.514 9.052 1.00 18.40 ? 27 GLN B N 1 ATOM 3555 C CA . GLN B 1 27 ? 21.610 -22.059 7.771 1.00 17.84 ? 27 GLN B CA 1 ATOM 3556 C C . GLN B 1 27 ? 20.691 -23.217 7.452 1.00 18.37 ? 27 GLN B C 1 ATOM 3557 O O . GLN B 1 27 ? 20.816 -23.874 6.372 1.00 18.38 ? 27 GLN B O 1 ATOM 3558 C CB . GLN B 1 27 ? 23.064 -22.510 7.717 1.00 18.01 ? 27 GLN B CB 1 ATOM 3559 C CG . GLN B 1 27 ? 23.425 -23.803 8.505 1.00 18.17 ? 27 GLN B CG 1 ATOM 3560 C CD . GLN B 1 27 ? 23.533 -23.545 10.006 1.00 21.56 ? 27 GLN B CD 1 ATOM 3561 O OE1 . GLN B 1 27 ? 24.034 -22.475 10.450 1.00 22.57 ? 27 GLN B OE1 1 ATOM 3562 N NE2 . GLN B 1 27 ? 23.025 -24.498 10.807 1.00 20.79 ? 27 GLN B NE2 1 ATOM 3563 N N . TYR B 1 28 ? 19.811 -23.491 8.405 1.00 17.98 ? 28 TYR B N 1 ATOM 3564 C CA . TYR B 1 28 ? 18.682 -24.379 8.180 1.00 19.31 ? 28 TYR B CA 1 ATOM 3565 C C . TYR B 1 28 ? 17.439 -23.625 7.721 1.00 19.43 ? 28 TYR B C 1 ATOM 3566 O O . TYR B 1 28 ? 16.416 -24.250 7.482 1.00 19.77 ? 28 TYR B O 1 ATOM 3567 C CB . TYR B 1 28 ? 18.369 -25.269 9.408 1.00 19.89 ? 28 TYR B CB 1 ATOM 3568 C CG . TYR B 1 28 ? 19.515 -26.210 9.807 1.00 20.77 ? 28 TYR B CG 1 ATOM 3569 C CD1 . TYR B 1 28 ? 20.328 -26.818 8.844 1.00 23.31 ? 28 TYR B CD1 1 ATOM 3570 C CD2 . TYR B 1 28 ? 19.799 -26.464 11.131 1.00 21.28 ? 28 TYR B CD2 1 ATOM 3571 C CE1 . TYR B 1 28 ? 21.383 -27.646 9.191 1.00 21.75 ? 28 TYR B CE1 1 ATOM 3572 C CE2 . TYR B 1 28 ? 20.859 -27.295 11.498 1.00 22.33 ? 28 TYR B CE2 1 ATOM 3573 C CZ . TYR B 1 28 ? 21.647 -27.877 10.534 1.00 22.94 ? 28 TYR B CZ 1 ATOM 3574 O OH . TYR B 1 28 ? 22.658 -28.724 10.906 1.00 22.28 ? 28 TYR B OH 1 ATOM 3575 N N . ALA B 1 29 ? 17.528 -22.299 7.573 1.00 19.49 ? 29 ALA B N 1 ATOM 3576 C CA . ALA B 1 29 ? 16.373 -21.522 7.111 1.00 19.70 ? 29 ALA B CA 1 ATOM 3577 C C . ALA B 1 29 ? 16.206 -21.624 5.607 1.00 20.15 ? 29 ALA B C 1 ATOM 3578 O O . ALA B 1 29 ? 17.190 -21.599 4.835 1.00 20.29 ? 29 ALA B O 1 ATOM 3579 C CB . ALA B 1 29 ? 16.472 -20.068 7.523 1.00 19.14 ? 29 ALA B CB 1 ATOM 3580 N N . PRO B 1 30 ? 14.947 -21.722 5.164 1.00 20.31 ? 30 PRO B N 1 ATOM 3581 C CA . PRO B 1 30 ? 14.736 -21.736 3.690 1.00 19.10 ? 30 PRO B CA 1 ATOM 3582 C C . PRO B 1 30 ? 15.065 -20.356 3.143 1.00 18.28 ? 30 PRO B C 1 ATOM 3583 O O . PRO B 1 30 ? 14.798 -19.374 3.829 1.00 18.19 ? 30 PRO B O 1 ATOM 3584 C CB . PRO B 1 30 ? 13.252 -22.016 3.538 1.00 19.63 ? 30 PRO B CB 1 ATOM 3585 C CG . PRO B 1 30 ? 12.617 -21.940 4.954 1.00 19.64 ? 30 PRO B CG 1 ATOM 3586 C CD . PRO B 1 30 ? 13.696 -21.649 5.956 1.00 20.43 ? 30 PRO B CD 1 ATOM 3587 N N . PHE B 1 31 ? 15.669 -20.256 1.961 1.00 17.21 ? 31 PHE B N 1 ATOM 3588 C CA . PHE B 1 31 ? 15.822 -18.935 1.353 1.00 17.04 ? 31 PHE B CA 1 ATOM 3589 C C . PHE B 1 31 ? 14.633 -17.988 1.605 1.00 16.93 ? 31 PHE B C 1 ATOM 3590 O O . PHE B 1 31 ? 13.495 -18.364 1.353 1.00 16.59 ? 31 PHE B O 1 ATOM 3591 C CB . PHE B 1 31 ? 15.967 -18.995 -0.159 1.00 16.79 ? 31 PHE B CB 1 ATOM 3592 C CG . PHE B 1 31 ? 15.949 -17.619 -0.781 1.00 17.15 ? 31 PHE B CG 1 ATOM 3593 C CD1 . PHE B 1 31 ? 17.007 -16.736 -0.558 1.00 15.56 ? 31 PHE B CD1 1 ATOM 3594 C CD2 . PHE B 1 31 ? 14.848 -17.171 -1.530 1.00 17.73 ? 31 PHE B CD2 1 ATOM 3595 C CE1 . PHE B 1 31 ? 17.004 -15.464 -1.104 1.00 17.22 ? 31 PHE B CE1 1 ATOM 3596 C CE2 . PHE B 1 31 ? 14.839 -15.877 -2.078 1.00 15.58 ? 31 PHE B CE2 1 ATOM 3597 C CZ . PHE B 1 31 ? 15.927 -15.024 -1.857 1.00 15.88 ? 31 PHE B CZ 1 ATOM 3598 N N . PHE B 1 32 ? 14.897 -16.765 2.055 1.00 17.18 ? 32 PHE B N 1 ATOM 3599 C CA . PHE B 1 32 ? 13.858 -15.726 2.131 1.00 18.16 ? 32 PHE B CA 1 ATOM 3600 C C . PHE B 1 32 ? 14.537 -14.429 1.727 1.00 18.51 ? 32 PHE B C 1 ATOM 3601 O O . PHE B 1 32 ? 15.558 -14.098 2.288 1.00 19.40 ? 32 PHE B O 1 ATOM 3602 C CB . PHE B 1 32 ? 13.202 -15.630 3.530 1.00 17.82 ? 32 PHE B CB 1 ATOM 3603 C CG . PHE B 1 32 ? 14.181 -15.335 4.658 1.00 19.03 ? 32 PHE B CG 1 ATOM 3604 C CD1 . PHE B 1 32 ? 14.853 -16.380 5.304 1.00 19.28 ? 32 PHE B CD1 1 ATOM 3605 C CD2 . PHE B 1 32 ? 14.428 -14.020 5.057 1.00 20.93 ? 32 PHE B CD2 1 ATOM 3606 C CE1 . PHE B 1 32 ? 15.765 -16.132 6.317 1.00 21.43 ? 32 PHE B CE1 1 ATOM 3607 C CE2 . PHE B 1 32 ? 15.330 -13.740 6.085 1.00 23.38 ? 32 PHE B CE2 1 ATOM 3608 C CZ . PHE B 1 32 ? 16.013 -14.808 6.713 1.00 23.35 ? 32 PHE B CZ 1 ATOM 3609 N N . SER B 1 33 ? 13.986 -13.738 0.728 1.00 19.21 ? 33 SER B N 1 ATOM 3610 C CA . SER B 1 33 ? 14.494 -12.477 0.183 1.00 18.92 ? 33 SER B CA 1 ATOM 3611 C C . SER B 1 33 ? 14.558 -11.334 1.145 1.00 19.54 ? 33 SER B C 1 ATOM 3612 O O . SER B 1 33 ? 13.597 -11.012 1.819 1.00 19.87 ? 33 SER B O 1 ATOM 3613 C CB . SER B 1 33 ? 13.631 -12.000 -0.990 1.00 18.82 ? 33 SER B CB 1 ATOM 3614 O OG . SER B 1 33 ? 14.059 -10.691 -1.360 1.00 16.73 ? 33 SER B OG 1 ATOM 3615 N N . LEU B 1 34 ? 15.697 -10.671 1.146 1.00 20.61 ? 34 LEU B N 1 ATOM 3616 C CA . LEU B 1 34 ? 15.891 -9.545 2.027 1.00 21.18 ? 34 LEU B CA 1 ATOM 3617 C C . LEU B 1 34 ? 15.663 -8.220 1.315 1.00 22.56 ? 34 LEU B C 1 ATOM 3618 O O . LEU B 1 34 ? 16.122 -7.172 1.796 1.00 21.97 ? 34 LEU B O 1 ATOM 3619 C CB . LEU B 1 34 ? 17.293 -9.603 2.611 1.00 20.40 ? 34 LEU B CB 1 ATOM 3620 C CG . LEU B 1 34 ? 17.503 -10.802 3.524 1.00 19.16 ? 34 LEU B CG 1 ATOM 3621 C CD1 . LEU B 1 34 ? 18.985 -10.964 3.863 1.00 18.53 ? 34 LEU B CD1 1 ATOM 3622 C CD2 . LEU B 1 34 ? 16.624 -10.620 4.757 1.00 19.70 ? 34 LEU B CD2 1 ATOM 3623 N N . ALA B 1 35 ? 14.966 -8.263 0.172 1.00 24.13 ? 35 ALA B N 1 ATOM 3624 C CA . ALA B 1 35 ? 14.856 -7.089 -0.679 1.00 26.09 ? 35 ALA B CA 1 ATOM 3625 C C . ALA B 1 35 ? 14.209 -5.911 0.071 1.00 28.01 ? 35 ALA B C 1 ATOM 3626 O O . ALA B 1 35 ? 14.702 -4.780 -0.024 1.00 28.44 ? 35 ALA B O 1 ATOM 3627 C CB . ALA B 1 35 ? 14.108 -7.412 -1.982 1.00 25.44 ? 35 ALA B CB 1 ATOM 3628 N N . ASN B 1 36 ? 13.139 -6.203 0.823 1.00 30.02 ? 36 ASN B N 1 ATOM 3629 C CA A ASN B 1 36 ? 12.429 -5.187 1.593 0.50 31.53 ? 36 ASN B CA 1 ATOM 3630 C CA B ASN B 1 36 ? 12.406 -5.209 1.620 0.50 31.79 ? 36 ASN B CA 1 ATOM 3631 C C . ASN B 1 36 ? 13.199 -4.705 2.848 1.00 33.02 ? 36 ASN B C 1 ATOM 3632 O O . ASN B 1 36 ? 12.812 -3.699 3.504 1.00 33.36 ? 36 ASN B O 1 ATOM 3633 C CB A ASN B 1 36 ? 11.005 -5.673 1.886 0.50 31.24 ? 36 ASN B CB 1 ATOM 3634 C CB B ASN B 1 36 ? 11.000 -5.733 1.996 0.50 31.64 ? 36 ASN B CB 1 ATOM 3635 C CG A ASN B 1 36 ? 10.180 -5.803 0.617 0.50 30.97 ? 36 ASN B CG 1 ATOM 3636 C CG B ASN B 1 36 ? 10.987 -6.553 3.284 0.50 32.64 ? 36 ASN B CG 1 ATOM 3637 O OD1 A ASN B 1 36 ? 9.890 -4.812 -0.040 0.50 30.78 ? 36 ASN B OD1 1 ATOM 3638 O OD1 B ASN B 1 36 ? 10.753 -7.767 3.261 0.50 32.31 ? 36 ASN B OD1 1 ATOM 3639 N ND2 A ASN B 1 36 ? 9.834 -7.031 0.246 0.50 31.93 ? 36 ASN B ND2 1 ATOM 3640 N ND2 B ASN B 1 36 ? 11.212 -5.884 4.419 0.50 33.49 ? 36 ASN B ND2 1 ATOM 3641 N N . GLU B 1 37 ? 14.314 -5.391 3.143 1.00 33.87 ? 37 GLU B N 1 ATOM 3642 C CA . GLU B 1 37 ? 15.232 -5.008 4.197 1.00 35.01 ? 37 GLU B CA 1 ATOM 3643 C C . GLU B 1 37 ? 16.419 -4.206 3.676 1.00 35.19 ? 37 GLU B C 1 ATOM 3644 O O . GLU B 1 37 ? 17.237 -3.713 4.472 1.00 35.09 ? 37 GLU B O 1 ATOM 3645 C CB . GLU B 1 37 ? 15.728 -6.257 4.929 1.00 35.48 ? 37 GLU B CB 1 ATOM 3646 C CG . GLU B 1 37 ? 14.631 -7.006 5.671 1.00 38.40 ? 37 GLU B CG 1 ATOM 3647 C CD . GLU B 1 37 ? 14.180 -6.267 6.924 1.00 42.15 ? 37 GLU B CD 1 ATOM 3648 O OE1 . GLU B 1 37 ? 14.748 -5.184 7.234 1.00 43.06 ? 37 GLU B OE1 1 ATOM 3649 O OE2 . GLU B 1 37 ? 13.255 -6.776 7.596 1.00 45.02 ? 37 GLU B OE2 1 ATOM 3650 N N . SER B 1 38 ? 16.516 -4.075 2.349 1.00 35.26 ? 38 SER B N 1 ATOM 3651 C CA . SER B 1 38 ? 17.613 -3.337 1.719 1.00 35.38 ? 38 SER B CA 1 ATOM 3652 C C . SER B 1 38 ? 17.368 -1.833 1.877 1.00 36.16 ? 38 SER B C 1 ATOM 3653 O O . SER B 1 38 ? 16.329 -1.309 1.444 1.00 37.05 ? 38 SER B O 1 ATOM 3654 C CB . SER B 1 38 ? 17.729 -3.727 0.234 1.00 35.51 ? 38 SER B CB 1 ATOM 3655 O OG . SER B 1 38 ? 19.005 -3.412 -0.335 1.00 34.00 ? 38 SER B OG 1 ATOM 3656 N N . VAL B 1 39 ? 18.306 -1.129 2.508 1.00 36.26 ? 39 VAL B N 1 ATOM 3657 C CA . VAL B 1 39 ? 18.191 0.328 2.616 1.00 35.70 ? 39 VAL B CA 1 ATOM 3658 C C . VAL B 1 39 ? 18.581 0.965 1.293 1.00 35.28 ? 39 VAL B C 1 ATOM 3659 O O . VAL B 1 39 ? 18.112 2.050 0.936 1.00 35.98 ? 39 VAL B O 1 ATOM 3660 C CB . VAL B 1 39 ? 19.012 0.885 3.800 1.00 35.87 ? 39 VAL B CB 1 ATOM 3661 C CG1 . VAL B 1 39 ? 18.990 2.412 3.841 1.00 35.01 ? 39 VAL B CG1 1 ATOM 3662 C CG2 . VAL B 1 39 ? 18.461 0.309 5.112 1.00 37.01 ? 39 VAL B CG2 1 ATOM 3663 N N . ILE B 1 40 ? 19.431 0.295 0.547 1.00 34.69 ? 40 ILE B N 1 ATOM 3664 C CA . ILE B 1 40 ? 19.719 0.761 -0.806 1.00 34.55 ? 40 ILE B CA 1 ATOM 3665 C C . ILE B 1 40 ? 18.814 -0.004 -1.783 1.00 34.82 ? 40 ILE B C 1 ATOM 3666 O O . ILE B 1 40 ? 18.568 -1.197 -1.622 1.00 34.21 ? 40 ILE B O 1 ATOM 3667 C CB . ILE B 1 40 ? 21.233 0.654 -1.121 1.00 34.31 ? 40 ILE B CB 1 ATOM 3668 C CG1 . ILE B 1 40 ? 22.024 1.547 -0.135 1.00 33.53 ? 40 ILE B CG1 1 ATOM 3669 C CG2 . ILE B 1 40 ? 21.545 1.000 -2.608 1.00 32.85 ? 40 ILE B CG2 1 ATOM 3670 C CD1 . ILE B 1 40 ? 23.494 1.188 0.005 1.00 31.27 ? 40 ILE B CD1 1 ATOM 3671 N N . SER B 1 41 ? 18.268 0.701 -2.758 1.00 35.81 ? 41 SER B N 1 ATOM 3672 C CA . SER B 1 41 ? 17.376 0.056 -3.706 1.00 36.94 ? 41 SER B CA 1 ATOM 3673 C C . SER B 1 41 ? 18.164 -0.914 -4.588 1.00 37.22 ? 41 SER B C 1 ATOM 3674 O O . SER B 1 41 ? 19.222 -0.557 -5.115 1.00 37.49 ? 41 SER B O 1 ATOM 3675 C CB . SER B 1 41 ? 16.632 1.081 -4.545 1.00 36.92 ? 41 SER B CB 1 ATOM 3676 O OG . SER B 1 41 ? 15.646 0.435 -5.325 1.00 38.38 ? 41 SER B OG 1 ATOM 3677 N N . PRO B 1 42 ? 17.664 -2.152 -4.717 1.00 38.09 ? 42 PRO B N 1 ATOM 3678 C CA . PRO B 1 42 ? 18.277 -3.151 -5.616 1.00 38.84 ? 42 PRO B CA 1 ATOM 3679 C C . PRO B 1 42 ? 18.112 -2.812 -7.098 1.00 39.35 ? 42 PRO B C 1 ATOM 3680 O O . PRO B 1 42 ? 18.886 -3.290 -7.918 1.00 39.59 ? 42 PRO B O 1 ATOM 3681 C CB . PRO B 1 42 ? 17.536 -4.448 -5.269 1.00 38.77 ? 42 PRO B CB 1 ATOM 3682 C CG . PRO B 1 42 ? 16.224 -3.979 -4.654 1.00 38.26 ? 42 PRO B CG 1 ATOM 3683 C CD . PRO B 1 42 ? 16.559 -2.724 -3.924 1.00 37.84 ? 42 PRO B CD 1 ATOM 3684 N N . GLU B 1 43 ? 17.111 -2.011 -7.444 1.00 39.89 ? 43 GLU B N 1 ATOM 3685 C CA . GLU B 1 43 ? 16.951 -1.582 -8.827 1.00 41.12 ? 43 GLU B CA 1 ATOM 3686 C C . GLU B 1 43 ? 18.222 -0.972 -9.425 1.00 41.41 ? 43 GLU B C 1 ATOM 3687 O O . GLU B 1 43 ? 19.049 -0.337 -8.726 1.00 41.38 ? 43 GLU B O 1 ATOM 3688 C CB . GLU B 1 43 ? 15.772 -0.618 -9.009 1.00 41.09 ? 43 GLU B CB 1 ATOM 3689 C CG . GLU B 1 43 ? 14.440 -1.317 -9.257 1.00 43.75 ? 43 GLU B CG 1 ATOM 3690 C CD . GLU B 1 43 ? 13.670 -1.553 -7.976 1.00 48.50 ? 43 GLU B CD 1 ATOM 3691 O OE1 . GLU B 1 43 ? 12.777 -0.720 -7.664 1.00 51.41 ? 43 GLU B OE1 1 ATOM 3692 O OE2 . GLU B 1 43 ? 13.961 -2.548 -7.271 1.00 48.91 ? 43 GLU B OE2 1 ATOM 3693 N N . VAL B 1 44 ? 18.365 -1.206 -10.722 1.00 41.20 ? 44 VAL B N 1 ATOM 3694 C CA . VAL B 1 44 ? 19.393 -0.607 -11.535 1.00 41.58 ? 44 VAL B CA 1 ATOM 3695 C C . VAL B 1 44 ? 19.079 0.889 -11.669 1.00 41.63 ? 44 VAL B C 1 ATOM 3696 O O . VAL B 1 44 ? 17.977 1.272 -12.088 1.00 41.72 ? 44 VAL B O 1 ATOM 3697 C CB . VAL B 1 44 ? 19.348 -1.240 -12.938 1.00 42.05 ? 44 VAL B CB 1 ATOM 3698 C CG1 . VAL B 1 44 ? 20.582 -0.858 -13.749 1.00 42.67 ? 44 VAL B CG1 1 ATOM 3699 C CG2 . VAL B 1 44 ? 19.159 -2.783 -12.844 1.00 42.39 ? 44 VAL B CG2 1 ATOM 3700 N N . PRO B 1 45 ? 20.034 1.756 -11.303 1.00 41.26 ? 45 PRO B N 1 ATOM 3701 C CA . PRO B 1 45 ? 19.744 3.172 -11.454 1.00 40.69 ? 45 PRO B CA 1 ATOM 3702 C C . PRO B 1 45 ? 19.561 3.598 -12.920 1.00 40.40 ? 45 PRO B C 1 ATOM 3703 O O . PRO B 1 45 ? 20.009 2.898 -13.853 1.00 39.54 ? 45 PRO B O 1 ATOM 3704 C CB . PRO B 1 45 ? 20.982 3.847 -10.841 1.00 40.81 ? 45 PRO B CB 1 ATOM 3705 C CG . PRO B 1 45 ? 21.521 2.849 -9.901 1.00 40.44 ? 45 PRO B CG 1 ATOM 3706 C CD . PRO B 1 45 ? 21.282 1.528 -10.555 1.00 41.10 ? 45 PRO B CD 1 ATOM 3707 N N . ALA B 1 46 ? 18.896 4.742 -13.102 1.00 39.67 ? 46 ALA B N 1 ATOM 3708 C CA . ALA B 1 46 ? 18.703 5.313 -14.425 1.00 39.12 ? 46 ALA B CA 1 ATOM 3709 C C . ALA B 1 46 ? 20.046 5.762 -14.952 1.00 38.13 ? 46 ALA B C 1 ATOM 3710 O O . ALA B 1 46 ? 20.912 6.169 -14.189 1.00 38.70 ? 46 ALA B O 1 ATOM 3711 C CB . ALA B 1 46 ? 17.744 6.479 -14.378 1.00 39.59 ? 46 ALA B CB 1 ATOM 3712 N N . GLY B 1 47 ? 20.222 5.665 -16.257 1.00 37.07 ? 47 GLY B N 1 ATOM 3713 C CA . GLY B 1 47 ? 21.477 6.016 -16.891 1.00 35.75 ? 47 GLY B CA 1 ATOM 3714 C C . GLY B 1 47 ? 22.418 4.842 -16.881 1.00 35.02 ? 47 GLY B C 1 ATOM 3715 O O . GLY B 1 47 ? 23.420 4.852 -17.605 1.00 35.43 ? 47 GLY B O 1 ATOM 3716 N N . CYS B 1 48 ? 22.070 3.816 -16.089 1.00 33.73 ? 48 CYS B N 1 ATOM 3717 C CA . CYS B 1 48 ? 22.943 2.665 -15.816 1.00 32.79 ? 48 CYS B CA 1 ATOM 3718 C C . CYS B 1 48 ? 22.518 1.360 -16.508 1.00 32.06 ? 48 CYS B C 1 ATOM 3719 O O . CYS B 1 48 ? 21.310 1.012 -16.588 1.00 31.31 ? 48 CYS B O 1 ATOM 3720 C CB . CYS B 1 48 ? 23.008 2.401 -14.296 1.00 33.42 ? 48 CYS B CB 1 ATOM 3721 S SG . CYS B 1 48 ? 23.883 3.650 -13.292 1.00 33.03 ? 48 CYS B SG 1 ATOM 3722 N N . ARG B 1 49 ? 23.519 0.599 -16.936 1.00 30.01 ? 49 ARG B N 1 ATOM 3723 C CA . ARG B 1 49 ? 23.245 -0.656 -17.597 1.00 29.07 ? 49 ARG B CA 1 ATOM 3724 C C . ARG B 1 49 ? 24.174 -1.781 -17.090 1.00 27.03 ? 49 ARG B C 1 ATOM 3725 O O . ARG B 1 49 ? 25.394 -1.638 -17.060 1.00 26.21 ? 49 ARG B O 1 ATOM 3726 C CB . ARG B 1 49 ? 23.382 -0.405 -19.106 1.00 30.00 ? 49 ARG B CB 1 ATOM 3727 C CG . ARG B 1 49 ? 22.866 -1.488 -20.064 1.00 33.68 ? 49 ARG B CG 1 ATOM 3728 C CD . ARG B 1 49 ? 23.483 -1.256 -21.467 1.00 40.26 ? 49 ARG B CD 1 ATOM 3729 N NE . ARG B 1 49 ? 24.694 -0.390 -21.439 1.00 45.46 ? 49 ARG B NE 1 ATOM 3730 C CZ . ARG B 1 49 ? 25.909 -0.712 -21.902 1.00 46.70 ? 49 ARG B CZ 1 ATOM 3731 N NH1 . ARG B 1 49 ? 26.158 -1.900 -22.460 1.00 47.16 ? 49 ARG B NH1 1 ATOM 3732 N NH2 . ARG B 1 49 ? 26.892 0.178 -21.814 1.00 49.25 ? 49 ARG B NH2 1 ATOM 3733 N N . VAL B 1 50 ? 23.577 -2.900 -16.688 1.00 25.87 ? 50 VAL B N 1 ATOM 3734 C CA . VAL B 1 50 ? 24.314 -4.077 -16.222 1.00 23.90 ? 50 VAL B CA 1 ATOM 3735 C C . VAL B 1 50 ? 25.055 -4.776 -17.397 1.00 23.59 ? 50 VAL B C 1 ATOM 3736 O O . VAL B 1 50 ? 24.444 -5.131 -18.420 1.00 23.03 ? 50 VAL B O 1 ATOM 3737 C CB . VAL B 1 50 ? 23.354 -5.088 -15.504 1.00 24.68 ? 50 VAL B CB 1 ATOM 3738 C CG1 . VAL B 1 50 ? 24.142 -6.246 -14.829 1.00 23.96 ? 50 VAL B CG1 1 ATOM 3739 C CG2 . VAL B 1 50 ? 22.473 -4.409 -14.477 1.00 23.51 ? 50 VAL B CG2 1 ATOM 3740 N N . THR B 1 51 ? 26.367 -4.964 -17.252 1.00 22.52 ? 51 THR B N 1 ATOM 3741 C CA . THR B 1 51 ? 27.191 -5.573 -18.299 1.00 22.38 ? 51 THR B CA 1 ATOM 3742 C C . THR B 1 51 ? 27.924 -6.856 -17.877 1.00 21.71 ? 51 THR B C 1 ATOM 3743 O O . THR B 1 51 ? 28.736 -7.381 -18.636 1.00 22.42 ? 51 THR B O 1 ATOM 3744 C CB . THR B 1 51 ? 28.228 -4.574 -18.836 1.00 22.88 ? 51 THR B CB 1 ATOM 3745 O OG1 . THR B 1 51 ? 29.198 -4.305 -17.824 1.00 23.63 ? 51 THR B OG1 1 ATOM 3746 C CG2 . THR B 1 51 ? 27.561 -3.260 -19.246 1.00 23.49 ? 51 THR B CG2 1 ATOM 3747 N N . PHE B 1 52 ? 27.659 -7.333 -16.658 1.00 20.93 ? 52 PHE B N 1 ATOM 3748 C CA . PHE B 1 52 ? 28.284 -8.541 -16.054 1.00 19.57 ? 52 PHE B CA 1 ATOM 3749 C C . PHE B 1 52 ? 27.353 -8.986 -14.942 1.00 18.64 ? 52 PHE B C 1 ATOM 3750 O O . PHE B 1 52 ? 26.837 -8.156 -14.208 1.00 18.33 ? 52 PHE B O 1 ATOM 3751 C CB . PHE B 1 52 ? 29.648 -8.180 -15.461 1.00 19.48 ? 52 PHE B CB 1 ATOM 3752 C CG . PHE B 1 52 ? 30.400 -9.331 -14.767 1.00 18.27 ? 52 PHE B CG 1 ATOM 3753 C CD1 . PHE B 1 52 ? 30.194 -9.600 -13.422 1.00 15.18 ? 52 PHE B CD1 1 ATOM 3754 C CD2 . PHE B 1 52 ? 31.397 -10.063 -15.456 1.00 18.29 ? 52 PHE B CD2 1 ATOM 3755 C CE1 . PHE B 1 52 ? 30.905 -10.631 -12.769 1.00 15.72 ? 52 PHE B CE1 1 ATOM 3756 C CE2 . PHE B 1 52 ? 32.128 -11.118 -14.818 1.00 15.94 ? 52 PHE B CE2 1 ATOM 3757 C CZ . PHE B 1 52 ? 31.883 -11.408 -13.491 1.00 16.51 ? 52 PHE B CZ 1 ATOM 3758 N N . ALA B 1 53 ? 27.135 -10.286 -14.840 1.00 17.57 ? 53 ALA B N 1 ATOM 3759 C CA . ALA B 1 53 ? 26.457 -10.848 -13.683 1.00 17.27 ? 53 ALA B CA 1 ATOM 3760 C C . ALA B 1 53 ? 26.967 -12.256 -13.370 1.00 15.98 ? 53 ALA B C 1 ATOM 3761 O O . ALA B 1 53 ? 26.934 -13.140 -14.209 1.00 15.57 ? 53 ALA B O 1 ATOM 3762 C CB . ALA B 1 53 ? 24.872 -10.787 -13.844 1.00 16.86 ? 53 ALA B CB 1 ATOM 3763 N N . GLN B 1 54 ? 27.518 -12.414 -12.170 1.00 15.79 ? 54 GLN B N 1 ATOM 3764 C CA . GLN B 1 54 ? 27.923 -13.717 -11.593 1.00 14.69 ? 54 GLN B CA 1 ATOM 3765 C C . GLN B 1 54 ? 26.991 -13.986 -10.425 1.00 14.13 ? 54 GLN B C 1 ATOM 3766 O O . GLN B 1 54 ? 26.757 -13.116 -9.594 1.00 14.14 ? 54 GLN B O 1 ATOM 3767 C CB . GLN B 1 54 ? 29.369 -13.685 -11.081 1.00 14.28 ? 54 GLN B CB 1 ATOM 3768 C CG . GLN B 1 54 ? 29.905 -14.946 -10.366 1.00 15.74 ? 54 GLN B CG 1 ATOM 3769 C CD . GLN B 1 54 ? 31.476 -15.056 -10.461 1.00 19.35 ? 54 GLN B CD 1 ATOM 3770 O OE1 . GLN B 1 54 ? 32.058 -15.131 -11.568 1.00 20.82 ? 54 GLN B OE1 1 ATOM 3771 N NE2 . GLN B 1 54 ? 32.152 -15.064 -9.304 1.00 16.86 ? 54 GLN B NE2 1 ATOM 3772 N N . VAL B 1 55 ? 26.464 -15.195 -10.358 1.00 13.99 ? 55 VAL B N 1 ATOM 3773 C CA . VAL B 1 55 ? 25.733 -15.625 -9.170 1.00 14.52 ? 55 VAL B CA 1 ATOM 3774 C C . VAL B 1 55 ? 26.466 -16.782 -8.491 1.00 14.62 ? 55 VAL B C 1 ATOM 3775 O O . VAL B 1 55 ? 26.857 -17.725 -9.155 1.00 15.15 ? 55 VAL B O 1 ATOM 3776 C CB . VAL B 1 55 ? 24.316 -16.057 -9.493 1.00 14.09 ? 55 VAL B CB 1 ATOM 3777 C CG1 . VAL B 1 55 ? 24.287 -17.053 -10.709 1.00 13.39 ? 55 VAL B CG1 1 ATOM 3778 C CG2 . VAL B 1 55 ? 23.677 -16.660 -8.266 1.00 13.76 ? 55 VAL B CG2 1 ATOM 3779 N N . LEU B 1 56 ? 26.676 -16.689 -7.184 1.00 14.71 ? 56 LEU B N 1 ATOM 3780 C CA . LEU B 1 56 ? 27.187 -17.820 -6.398 1.00 14.60 ? 56 LEU B CA 1 ATOM 3781 C C . LEU B 1 56 ? 26.054 -18.345 -5.525 1.00 15.27 ? 56 LEU B C 1 ATOM 3782 O O . LEU B 1 56 ? 25.444 -17.584 -4.741 1.00 15.86 ? 56 LEU B O 1 ATOM 3783 C CB . LEU B 1 56 ? 28.420 -17.422 -5.591 1.00 14.44 ? 56 LEU B CB 1 ATOM 3784 C CG . LEU B 1 56 ? 28.928 -18.478 -4.570 1.00 13.78 ? 56 LEU B CG 1 ATOM 3785 C CD1 . LEU B 1 56 ? 29.662 -19.652 -5.224 1.00 6.73 ? 56 LEU B CD1 1 ATOM 3786 C CD2 . LEU B 1 56 ? 29.815 -17.763 -3.618 1.00 10.84 ? 56 LEU B CD2 1 ATOM 3787 N N . SER B 1 57 ? 25.698 -19.622 -5.702 1.00 16.04 ? 57 SER B N 1 ATOM 3788 C CA . SER B 1 57 ? 24.484 -20.124 -5.068 1.00 15.83 ? 57 SER B CA 1 ATOM 3789 C C . SER B 1 57 ? 24.787 -21.283 -4.163 1.00 16.89 ? 57 SER B C 1 ATOM 3790 O O . SER B 1 57 ? 25.657 -22.107 -4.475 1.00 18.31 ? 57 SER B O 1 ATOM 3791 C CB . SER B 1 57 ? 23.447 -20.505 -6.149 1.00 16.80 ? 57 SER B CB 1 ATOM 3792 O OG . SER B 1 57 ? 22.212 -20.978 -5.618 1.00 13.60 ? 57 SER B OG 1 ATOM 3793 N N . ARG B 1 58 ? 24.091 -21.362 -3.022 1.00 17.53 ? 58 ARG B N 1 ATOM 3794 C CA . ARG B 1 58 ? 24.151 -22.577 -2.179 1.00 17.09 ? 58 ARG B CA 1 ATOM 3795 C C . ARG B 1 58 ? 23.264 -23.634 -2.812 1.00 17.36 ? 58 ARG B C 1 ATOM 3796 O O . ARG B 1 58 ? 22.453 -23.281 -3.669 1.00 16.86 ? 58 ARG B O 1 ATOM 3797 C CB . ARG B 1 58 ? 23.648 -22.279 -0.760 1.00 17.61 ? 58 ARG B CB 1 ATOM 3798 C CG . ARG B 1 58 ? 23.890 -23.426 0.229 1.00 15.23 ? 58 ARG B CG 1 ATOM 3799 C CD . ARG B 1 58 ? 23.746 -23.000 1.650 1.00 13.18 ? 58 ARG B CD 1 ATOM 3800 N NE . ARG B 1 58 ? 23.713 -24.209 2.440 1.00 15.54 ? 58 ARG B NE 1 ATOM 3801 C CZ . ARG B 1 58 ? 22.993 -24.387 3.538 1.00 11.62 ? 58 ARG B CZ 1 ATOM 3802 N NH1 . ARG B 1 58 ? 22.250 -23.409 4.029 1.00 10.21 ? 58 ARG B NH1 1 ATOM 3803 N NH2 . ARG B 1 58 ? 23.019 -25.573 4.127 1.00 9.24 ? 58 ARG B NH2 1 ATOM 3804 N N . HIS B 1 59 ? 23.418 -24.917 -2.432 1.00 17.20 ? 59 HIS B N 1 ATOM 3805 C CA . HIS B 1 59 ? 22.379 -25.912 -2.749 1.00 17.00 ? 59 HIS B CA 1 ATOM 3806 C C . HIS B 1 59 ? 21.089 -25.664 -1.990 1.00 16.94 ? 59 HIS B C 1 ATOM 3807 O O . HIS B 1 59 ? 21.026 -24.824 -1.095 1.00 16.43 ? 59 HIS B O 1 ATOM 3808 C CB . HIS B 1 59 ? 22.814 -27.328 -2.442 1.00 17.41 ? 59 HIS B CB 1 ATOM 3809 C CG . HIS B 1 59 ? 23.150 -27.543 -1.011 1.00 16.41 ? 59 HIS B CG 1 ATOM 3810 N ND1 . HIS B 1 59 ? 22.186 -27.688 -0.030 1.00 15.36 ? 59 HIS B ND1 1 ATOM 3811 C CD2 . HIS B 1 59 ? 24.350 -27.650 -0.398 1.00 11.79 ? 59 HIS B CD2 1 ATOM 3812 C CE1 . HIS B 1 59 ? 22.786 -27.859 1.135 1.00 13.65 ? 59 HIS B CE1 1 ATOM 3813 N NE2 . HIS B 1 59 ? 24.096 -27.856 0.934 1.00 13.79 ? 59 HIS B NE2 1 ATOM 3814 N N . GLY B 1 60 ? 20.055 -26.406 -2.361 1.00 17.35 ? 60 GLY B N 1 ATOM 3815 C CA . GLY B 1 60 ? 18.727 -26.180 -1.814 1.00 17.62 ? 60 GLY B CA 1 ATOM 3816 C C . GLY B 1 60 ? 18.590 -26.950 -0.529 1.00 18.56 ? 60 GLY B C 1 ATOM 3817 O O . GLY B 1 60 ? 19.526 -27.651 -0.127 1.00 18.51 ? 60 GLY B O 1 ATOM 3818 N N . ALA B 1 61 ? 17.440 -26.772 0.119 1.00 19.08 ? 61 ALA B N 1 ATOM 3819 C CA . ALA B 1 61 ? 17.052 -27.508 1.283 1.00 20.34 ? 61 ALA B CA 1 ATOM 3820 C C . ALA B 1 61 ? 17.278 -29.021 1.124 1.00 22.05 ? 61 ALA B C 1 ATOM 3821 O O . ALA B 1 61 ? 16.973 -29.609 0.090 1.00 22.79 ? 61 ALA B O 1 ATOM 3822 C CB . ALA B 1 61 ? 15.584 -27.194 1.605 1.00 19.82 ? 61 ALA B CB 1 ATOM 3823 N N . ARG B 1 62 ? 17.845 -29.648 2.149 1.00 23.70 ? 62 ARG B N 1 ATOM 3824 C CA . ARG B 1 62 ? 18.212 -31.054 2.089 1.00 24.86 ? 62 ARG B CA 1 ATOM 3825 C C . ARG B 1 62 ? 17.683 -31.791 3.307 1.00 25.32 ? 62 ARG B C 1 ATOM 3826 O O . ARG B 1 62 ? 17.397 -31.208 4.373 1.00 26.57 ? 62 ARG B O 1 ATOM 3827 C CB . ARG B 1 62 ? 19.728 -31.227 2.021 1.00 24.98 ? 62 ARG B CB 1 ATOM 3828 C CG . ARG B 1 62 ? 20.471 -30.702 3.279 1.00 26.16 ? 62 ARG B CG 1 ATOM 3829 C CD . ARG B 1 62 ? 21.891 -31.276 3.398 1.00 26.85 ? 62 ARG B CD 1 ATOM 3830 N NE . ARG B 1 62 ? 22.706 -30.770 4.533 1.00 28.97 ? 62 ARG B NE 1 ATOM 3831 C CZ . ARG B 1 62 ? 22.486 -30.994 5.845 1.00 30.44 ? 62 ARG B CZ 1 ATOM 3832 N NH1 . ARG B 1 62 ? 21.401 -31.654 6.276 1.00 31.88 ? 62 ARG B NH1 1 ATOM 3833 N NH2 . ARG B 1 62 ? 23.324 -30.503 6.760 1.00 29.71 ? 62 ARG B NH2 1 ATOM 3834 N N . TYR B 1 63 ? 17.565 -33.089 3.151 1.00 25.64 ? 63 TYR B N 1 ATOM 3835 C CA . TYR B 1 63 ? 17.367 -33.976 4.270 1.00 26.49 ? 63 TYR B CA 1 ATOM 3836 C C . TYR B 1 63 ? 18.570 -33.911 5.215 1.00 27.54 ? 63 TYR B C 1 ATOM 3837 O O . TYR B 1 63 ? 19.662 -33.470 4.824 1.00 27.20 ? 63 TYR B O 1 ATOM 3838 C CB . TYR B 1 63 ? 17.199 -35.374 3.734 1.00 26.30 ? 63 TYR B CB 1 ATOM 3839 C CG . TYR B 1 63 ? 15.891 -35.597 3.003 1.00 25.49 ? 63 TYR B CG 1 ATOM 3840 C CD1 . TYR B 1 63 ? 14.668 -35.299 3.626 1.00 23.02 ? 63 TYR B CD1 1 ATOM 3841 C CD2 . TYR B 1 63 ? 15.872 -36.104 1.689 1.00 25.08 ? 63 TYR B CD2 1 ATOM 3842 C CE1 . TYR B 1 63 ? 13.462 -35.505 2.989 1.00 23.86 ? 63 TYR B CE1 1 ATOM 3843 C CE2 . TYR B 1 63 ? 14.636 -36.331 1.021 1.00 26.42 ? 63 TYR B CE2 1 ATOM 3844 C CZ . TYR B 1 63 ? 13.445 -36.021 1.701 1.00 27.07 ? 63 TYR B CZ 1 ATOM 3845 O OH . TYR B 1 63 ? 12.234 -36.217 1.103 1.00 31.70 ? 63 TYR B OH 1 ATOM 3846 N N . PRO B 1 64 ? 18.373 -34.319 6.477 1.00 28.46 ? 64 PRO B N 1 ATOM 3847 C CA . PRO B 1 64 ? 19.499 -34.342 7.420 1.00 29.38 ? 64 PRO B CA 1 ATOM 3848 C C . PRO B 1 64 ? 20.570 -35.327 6.953 1.00 30.33 ? 64 PRO B C 1 ATOM 3849 O O . PRO B 1 64 ? 20.232 -36.306 6.301 1.00 30.27 ? 64 PRO B O 1 ATOM 3850 C CB . PRO B 1 64 ? 18.847 -34.835 8.712 1.00 29.32 ? 64 PRO B CB 1 ATOM 3851 C CG . PRO B 1 64 ? 17.351 -34.613 8.534 1.00 28.61 ? 64 PRO B CG 1 ATOM 3852 C CD . PRO B 1 64 ? 17.118 -34.803 7.083 1.00 28.43 ? 64 PRO B CD 1 ATOM 3853 N N . THR B 1 65 ? 21.837 -35.096 7.258 1.00 31.70 ? 65 THR B N 1 ATOM 3854 C CA . THR B 1 65 ? 22.839 -36.052 6.816 1.00 34.25 ? 65 THR B CA 1 ATOM 3855 C C . THR B 1 65 ? 22.594 -37.378 7.516 1.00 35.78 ? 65 THR B C 1 ATOM 3856 O O . THR B 1 65 ? 21.848 -37.427 8.497 1.00 36.61 ? 65 THR B O 1 ATOM 3857 C CB . THR B 1 65 ? 24.278 -35.617 7.094 1.00 34.20 ? 65 THR B CB 1 ATOM 3858 O OG1 . THR B 1 65 ? 24.634 -36.055 8.403 1.00 36.72 ? 65 THR B OG1 1 ATOM 3859 C CG2 . THR B 1 65 ? 24.462 -34.097 6.978 1.00 34.45 ? 65 THR B CG2 1 ATOM 3860 N N . ASP B 1 66 ? 23.201 -38.457 7.016 1.00 37.30 ? 66 ASP B N 1 ATOM 3861 C CA . ASP B 1 66 ? 22.961 -39.794 7.568 1.00 38.82 ? 66 ASP B CA 1 ATOM 3862 C C . ASP B 1 66 ? 23.293 -39.890 9.073 1.00 39.17 ? 66 ASP B C 1 ATOM 3863 O O . ASP B 1 66 ? 22.476 -40.334 9.872 1.00 39.03 ? 66 ASP B O 1 ATOM 3864 C CB . ASP B 1 66 ? 23.746 -40.832 6.788 1.00 39.38 ? 66 ASP B CB 1 ATOM 3865 C CG . ASP B 1 66 ? 23.313 -42.237 7.110 1.00 41.05 ? 66 ASP B CG 1 ATOM 3866 O OD1 . ASP B 1 66 ? 22.111 -42.538 6.890 1.00 44.48 ? 66 ASP B OD1 1 ATOM 3867 O OD2 . ASP B 1 66 ? 24.163 -43.030 7.585 1.00 40.86 ? 66 ASP B OD2 1 ATOM 3868 N N . SER B 1 67 ? 24.500 -39.456 9.427 1.00 39.96 ? 67 SER B N 1 ATOM 3869 C CA . SER B 1 67 ? 24.915 -39.197 10.806 1.00 40.77 ? 67 SER B CA 1 ATOM 3870 C C . SER B 1 67 ? 23.773 -38.641 11.677 1.00 41.16 ? 67 SER B C 1 ATOM 3871 O O . SER B 1 67 ? 23.248 -39.341 12.540 1.00 41.03 ? 67 SER B O 1 ATOM 3872 C CB . SER B 1 67 ? 26.065 -38.191 10.765 1.00 41.04 ? 67 SER B CB 1 ATOM 3873 O OG . SER B 1 67 ? 27.005 -38.438 11.777 1.00 42.46 ? 67 SER B OG 1 ATOM 3874 N N . LYS B 1 68 ? 23.375 -37.391 11.394 1.00 41.50 ? 68 LYS B N 1 ATOM 3875 C CA . LYS B 1 68 ? 22.452 -36.602 12.221 1.00 41.18 ? 68 LYS B CA 1 ATOM 3876 C C . LYS B 1 68 ? 21.076 -37.216 12.328 1.00 41.23 ? 68 LYS B C 1 ATOM 3877 O O . LYS B 1 68 ? 20.451 -37.177 13.400 1.00 40.61 ? 68 LYS B O 1 ATOM 3878 C CB . LYS B 1 68 ? 22.322 -35.165 11.693 1.00 41.10 ? 68 LYS B CB 1 ATOM 3879 C CG . LYS B 1 68 ? 23.606 -34.329 11.729 1.00 40.65 ? 68 LYS B CG 1 ATOM 3880 C CD . LYS B 1 68 ? 23.819 -33.743 13.105 1.00 41.56 ? 68 LYS B CD 1 ATOM 3881 C CE . LYS B 1 68 ? 24.671 -32.484 13.088 1.00 41.26 ? 68 LYS B CE 1 ATOM 3882 N NZ . LYS B 1 68 ? 24.145 -31.620 14.191 1.00 43.76 ? 68 LYS B NZ 1 ATOM 3883 N N . GLY B 1 69 ? 20.607 -37.771 11.214 1.00 41.49 ? 69 GLY B N 1 ATOM 3884 C CA . GLY B 1 69 ? 19.305 -38.435 11.162 1.00 41.55 ? 69 GLY B CA 1 ATOM 3885 C C . GLY B 1 69 ? 19.243 -39.663 12.055 1.00 42.05 ? 69 GLY B C 1 ATOM 3886 O O . GLY B 1 69 ? 18.232 -39.882 12.711 1.00 41.55 ? 69 GLY B O 1 ATOM 3887 N N . LYS B 1 70 ? 20.317 -40.471 12.058 1.00 42.72 ? 70 LYS B N 1 ATOM 3888 C CA . LYS B 1 70 ? 20.483 -41.607 12.992 1.00 43.34 ? 70 LYS B CA 1 ATOM 3889 C C . LYS B 1 70 ? 20.126 -41.081 14.388 1.00 43.17 ? 70 LYS B C 1 ATOM 3890 O O . LYS B 1 70 ? 19.147 -41.514 15.018 1.00 43.25 ? 70 LYS B O 1 ATOM 3891 C CB . LYS B 1 70 ? 21.945 -42.112 13.047 1.00 43.72 ? 70 LYS B CB 1 ATOM 3892 C CG . LYS B 1 70 ? 22.596 -42.573 11.745 1.00 44.64 ? 70 LYS B CG 1 ATOM 3893 C CD . LYS B 1 70 ? 22.355 -44.051 11.496 1.00 45.66 ? 70 LYS B CD 1 ATOM 3894 C CE . LYS B 1 70 ? 22.815 -44.457 10.120 1.00 44.23 ? 70 LYS B CE 1 ATOM 3895 N NZ . LYS B 1 70 ? 22.320 -45.815 9.821 1.00 45.73 ? 70 LYS B NZ 1 ATOM 3896 N N . LYS B 1 71 ? 20.927 -40.120 14.835 1.00 42.38 ? 71 LYS B N 1 ATOM 3897 C CA . LYS B 1 71 ? 20.765 -39.505 16.147 1.00 41.70 ? 71 LYS B CA 1 ATOM 3898 C C . LYS B 1 71 ? 19.338 -38.981 16.400 1.00 41.03 ? 71 LYS B C 1 ATOM 3899 O O . LYS B 1 71 ? 18.732 -39.354 17.391 1.00 41.56 ? 71 LYS B O 1 ATOM 3900 C CB . LYS B 1 71 ? 21.881 -38.468 16.392 1.00 41.19 ? 71 LYS B CB 1 ATOM 3901 C CG . LYS B 1 71 ? 23.266 -39.128 16.345 1.00 40.83 ? 71 LYS B CG 1 ATOM 3902 C CD . LYS B 1 71 ? 24.420 -38.167 16.188 1.00 41.45 ? 71 LYS B CD 1 ATOM 3903 C CE . LYS B 1 71 ? 25.683 -38.929 15.785 1.00 42.59 ? 71 LYS B CE 1 ATOM 3904 N NZ . LYS B 1 71 ? 26.925 -38.103 15.866 1.00 43.43 ? 71 LYS B NZ 1 ATOM 3905 N N . TYR B 1 72 ? 18.791 -38.179 15.490 1.00 40.35 ? 72 TYR B N 1 ATOM 3906 C CA . TYR B 1 72 ? 17.435 -37.645 15.648 1.00 39.46 ? 72 TYR B CA 1 ATOM 3907 C C . TYR B 1 72 ? 16.442 -38.776 15.881 1.00 39.12 ? 72 TYR B C 1 ATOM 3908 O O . TYR B 1 72 ? 15.644 -38.735 16.811 1.00 38.13 ? 72 TYR B O 1 ATOM 3909 C CB . TYR B 1 72 ? 16.948 -36.840 14.416 1.00 39.49 ? 72 TYR B CB 1 ATOM 3910 C CG . TYR B 1 72 ? 17.706 -35.582 14.033 1.00 38.00 ? 72 TYR B CG 1 ATOM 3911 C CD1 . TYR B 1 72 ? 18.355 -34.820 14.977 1.00 37.43 ? 72 TYR B CD1 1 ATOM 3912 C CD2 . TYR B 1 72 ? 17.729 -35.135 12.711 1.00 37.35 ? 72 TYR B CD2 1 ATOM 3913 C CE1 . TYR B 1 72 ? 19.040 -33.671 14.621 1.00 36.54 ? 72 TYR B CE1 1 ATOM 3914 C CE2 . TYR B 1 72 ? 18.411 -33.977 12.355 1.00 35.11 ? 72 TYR B CE2 1 ATOM 3915 C CZ . TYR B 1 72 ? 19.055 -33.253 13.321 1.00 34.75 ? 72 TYR B CZ 1 ATOM 3916 O OH . TYR B 1 72 ? 19.747 -32.108 13.010 1.00 33.13 ? 72 TYR B OH 1 ATOM 3917 N N . SER B 1 73 ? 16.502 -39.762 14.988 1.00 39.37 ? 73 SER B N 1 ATOM 3918 C CA . SER B 1 73 ? 15.687 -40.972 15.025 1.00 39.55 ? 73 SER B CA 1 ATOM 3919 C C . SER B 1 73 ? 15.887 -41.713 16.371 1.00 39.22 ? 73 SER B C 1 ATOM 3920 O O . SER B 1 73 ? 14.907 -41.999 17.075 1.00 38.43 ? 73 SER B O 1 ATOM 3921 C CB . SER B 1 73 ? 16.031 -41.842 13.799 1.00 39.58 ? 73 SER B CB 1 ATOM 3922 O OG . SER B 1 73 ? 15.419 -43.118 13.833 1.00 41.78 ? 73 SER B OG 1 ATOM 3923 N N . ALA B 1 74 ? 17.153 -41.958 16.731 1.00 38.95 ? 74 ALA B N 1 ATOM 3924 C CA . ALA B 1 74 ? 17.524 -42.536 18.034 1.00 39.29 ? 74 ALA B CA 1 ATOM 3925 C C . ALA B 1 74 ? 16.966 -41.746 19.193 1.00 39.27 ? 74 ALA B C 1 ATOM 3926 O O . ALA B 1 74 ? 16.391 -42.322 20.110 1.00 39.78 ? 74 ALA B O 1 ATOM 3927 C CB . ALA B 1 74 ? 19.051 -42.654 18.193 1.00 38.95 ? 74 ALA B CB 1 ATOM 3928 N N . LEU B 1 75 ? 17.154 -40.433 19.165 1.00 39.13 ? 75 LEU B N 1 ATOM 3929 C CA . LEU B 1 75 ? 16.684 -39.596 20.257 1.00 39.21 ? 75 LEU B CA 1 ATOM 3930 C C . LEU B 1 75 ? 15.181 -39.769 20.432 1.00 39.68 ? 75 LEU B C 1 ATOM 3931 O O . LEU B 1 75 ? 14.698 -40.003 21.548 1.00 39.61 ? 75 LEU B O 1 ATOM 3932 C CB . LEU B 1 75 ? 17.063 -38.118 20.046 1.00 38.84 ? 75 LEU B CB 1 ATOM 3933 C CG . LEU B 1 75 ? 16.600 -37.042 21.049 1.00 38.51 ? 75 LEU B CG 1 ATOM 3934 C CD1 . LEU B 1 75 ? 16.925 -37.424 22.487 1.00 37.69 ? 75 LEU B CD1 1 ATOM 3935 C CD2 . LEU B 1 75 ? 17.182 -35.680 20.748 1.00 37.59 ? 75 LEU B CD2 1 ATOM 3936 N N . ILE B 1 76 ? 14.437 -39.674 19.339 1.00 40.35 ? 76 ILE B N 1 ATOM 3937 C CA . ILE B 1 76 ? 12.981 -39.678 19.460 1.00 41.09 ? 76 ILE B CA 1 ATOM 3938 C C . ILE B 1 76 ? 12.476 -41.031 19.941 1.00 41.62 ? 76 ILE B C 1 ATOM 3939 O O . ILE B 1 76 ? 11.451 -41.083 20.614 1.00 41.81 ? 76 ILE B O 1 ATOM 3940 C CB . ILE B 1 76 ? 12.254 -39.204 18.179 1.00 40.78 ? 76 ILE B CB 1 ATOM 3941 C CG1 . ILE B 1 76 ? 12.778 -37.841 17.767 1.00 41.14 ? 76 ILE B CG1 1 ATOM 3942 C CG2 . ILE B 1 76 ? 10.768 -39.058 18.433 1.00 40.95 ? 76 ILE B CG2 1 ATOM 3943 C CD1 . ILE B 1 76 ? 12.824 -37.633 16.267 1.00 42.54 ? 76 ILE B CD1 1 ATOM 3944 N N . GLU B 1 77 ? 13.196 -42.110 19.635 1.00 42.14 ? 77 GLU B N 1 ATOM 3945 C CA . GLU B 1 77 ? 12.837 -43.416 20.183 1.00 43.58 ? 77 GLU B CA 1 ATOM 3946 C C . GLU B 1 77 ? 12.988 -43.420 21.719 1.00 43.67 ? 77 GLU B C 1 ATOM 3947 O O . GLU B 1 77 ? 12.084 -43.831 22.447 1.00 43.70 ? 77 GLU B O 1 ATOM 3948 C CB . GLU B 1 77 ? 13.671 -44.544 19.554 1.00 44.03 ? 77 GLU B CB 1 ATOM 3949 C CG . GLU B 1 77 ? 13.453 -44.729 18.061 1.00 46.32 ? 77 GLU B CG 1 ATOM 3950 C CD . GLU B 1 77 ? 13.500 -46.183 17.667 1.00 51.32 ? 77 GLU B CD 1 ATOM 3951 O OE1 . GLU B 1 77 ? 14.516 -46.846 18.006 1.00 52.08 ? 77 GLU B OE1 1 ATOM 3952 O OE2 . GLU B 1 77 ? 12.511 -46.676 17.049 1.00 52.36 ? 77 GLU B OE2 1 ATOM 3953 N N . GLU B 1 78 ? 14.139 -42.952 22.195 1.00 44.01 ? 78 GLU B N 1 ATOM 3954 C CA . GLU B 1 78 ? 14.421 -42.858 23.627 1.00 44.13 ? 78 GLU B CA 1 ATOM 3955 C C . GLU B 1 78 ? 13.414 -41.974 24.336 1.00 43.84 ? 78 GLU B C 1 ATOM 3956 O O . GLU B 1 78 ? 12.987 -42.275 25.449 1.00 43.35 ? 78 GLU B O 1 ATOM 3957 C CB . GLU B 1 78 ? 15.829 -42.334 23.864 1.00 44.26 ? 78 GLU B CB 1 ATOM 3958 C CG . GLU B 1 78 ? 16.894 -43.381 23.650 1.00 46.62 ? 78 GLU B CG 1 ATOM 3959 C CD . GLU B 1 78 ? 18.304 -42.893 23.970 1.00 50.70 ? 78 GLU B CD 1 ATOM 3960 O OE1 . GLU B 1 78 ? 19.233 -43.478 23.374 1.00 54.09 ? 78 GLU B OE1 1 ATOM 3961 O OE2 . GLU B 1 78 ? 18.507 -41.956 24.799 1.00 50.87 ? 78 GLU B OE2 1 ATOM 3962 N N . ILE B 1 79 ? 13.032 -40.881 23.682 1.00 43.60 ? 79 ILE B N 1 ATOM 3963 C CA . ILE B 1 79 ? 11.989 -40.038 24.218 1.00 43.69 ? 79 ILE B CA 1 ATOM 3964 C C . ILE B 1 79 ? 10.680 -40.829 24.399 1.00 44.26 ? 79 ILE B C 1 ATOM 3965 O O . ILE B 1 79 ? 10.024 -40.710 25.421 1.00 43.76 ? 79 ILE B O 1 ATOM 3966 C CB . ILE B 1 79 ? 11.837 -38.724 23.408 1.00 43.50 ? 79 ILE B CB 1 ATOM 3967 C CG1 . ILE B 1 79 ? 13.045 -37.829 23.702 1.00 42.26 ? 79 ILE B CG1 1 ATOM 3968 C CG2 . ILE B 1 79 ? 10.554 -37.991 23.776 1.00 42.79 ? 79 ILE B CG2 1 ATOM 3969 C CD1 . ILE B 1 79 ? 13.310 -36.764 22.698 1.00 40.88 ? 79 ILE B CD1 1 ATOM 3970 N N . GLN B 1 80 ? 10.356 -41.678 23.432 1.00 45.31 ? 80 GLN B N 1 ATOM 3971 C CA . GLN B 1 80 ? 9.120 -42.465 23.447 1.00 46.38 ? 80 GLN B CA 1 ATOM 3972 C C . GLN B 1 80 ? 9.180 -43.681 24.384 1.00 46.51 ? 80 GLN B C 1 ATOM 3973 O O . GLN B 1 80 ? 8.165 -44.104 24.929 1.00 45.74 ? 80 GLN B O 1 ATOM 3974 C CB . GLN B 1 80 ? 8.757 -42.896 22.019 1.00 46.63 ? 80 GLN B CB 1 ATOM 3975 C CG . GLN B 1 80 ? 8.312 -41.734 21.123 1.00 47.88 ? 80 GLN B CG 1 ATOM 3976 C CD . GLN B 1 80 ? 8.155 -42.098 19.644 1.00 49.03 ? 80 GLN B CD 1 ATOM 3977 O OE1 . GLN B 1 80 ? 8.689 -43.111 19.160 1.00 48.21 ? 80 GLN B OE1 1 ATOM 3978 N NE2 . GLN B 1 80 ? 7.411 -41.263 18.923 1.00 48.58 ? 80 GLN B NE2 1 ATOM 3979 N N . GLN B 1 81 ? 10.371 -44.240 24.566 1.00 47.27 ? 81 GLN B N 1 ATOM 3980 C CA . GLN B 1 81 ? 10.538 -45.340 25.514 1.00 48.13 ? 81 GLN B CA 1 ATOM 3981 C C . GLN B 1 81 ? 10.420 -44.892 26.979 1.00 47.96 ? 81 GLN B C 1 ATOM 3982 O O . GLN B 1 81 ? 9.848 -45.614 27.786 1.00 48.13 ? 81 GLN B O 1 ATOM 3983 C CB . GLN B 1 81 ? 11.864 -46.054 25.298 1.00 48.44 ? 81 GLN B CB 1 ATOM 3984 C CG . GLN B 1 81 ? 11.811 -47.146 24.273 1.00 50.99 ? 81 GLN B CG 1 ATOM 3985 C CD . GLN B 1 81 ? 13.211 -47.559 23.825 1.00 55.54 ? 81 GLN B CD 1 ATOM 3986 O OE1 . GLN B 1 81 ? 14.175 -47.561 24.625 1.00 56.22 ? 81 GLN B OE1 1 ATOM 3987 N NE2 . GLN B 1 81 ? 13.337 -47.911 22.536 1.00 56.99 ? 81 GLN B NE2 1 ATOM 3988 N N . ASN B 1 82 ? 10.920 -43.695 27.303 1.00 47.63 ? 82 ASN B N 1 ATOM 3989 C CA . ASN B 1 82 ? 11.102 -43.276 28.694 1.00 47.34 ? 82 ASN B CA 1 ATOM 3990 C C . ASN B 1 82 ? 9.981 -42.430 29.309 1.00 48.10 ? 82 ASN B C 1 ATOM 3991 O O . ASN B 1 82 ? 9.648 -42.599 30.488 1.00 48.31 ? 82 ASN B O 1 ATOM 3992 C CB . ASN B 1 82 ? 12.464 -42.579 28.905 1.00 47.01 ? 82 ASN B CB 1 ATOM 3993 C CG . ASN B 1 82 ? 13.670 -43.448 28.509 1.00 44.96 ? 82 ASN B CG 1 ATOM 3994 O OD1 . ASN B 1 82 ? 13.536 -44.599 28.070 1.00 42.87 ? 82 ASN B OD1 1 ATOM 3995 N ND2 . ASN B 1 82 ? 14.858 -42.874 28.660 1.00 43.98 ? 82 ASN B ND2 1 ATOM 3996 N N . ALA B 1 83 ? 9.401 -41.519 28.534 1.00 48.71 ? 83 ALA B N 1 ATOM 3997 C CA . ALA B 1 83 ? 8.462 -40.531 29.101 1.00 49.32 ? 83 ALA B CA 1 ATOM 3998 C C . ALA B 1 83 ? 7.093 -41.119 29.482 1.00 50.18 ? 83 ALA B C 1 ATOM 3999 O O . ALA B 1 83 ? 6.664 -42.137 28.932 1.00 50.00 ? 83 ALA B O 1 ATOM 4000 C CB . ALA B 1 83 ? 8.302 -39.329 28.166 1.00 48.82 ? 83 ALA B CB 1 ATOM 4001 N N . THR B 1 84 ? 6.416 -40.474 30.429 1.00 51.30 ? 84 THR B N 1 ATOM 4002 C CA . THR B 1 84 ? 5.131 -40.984 30.922 1.00 52.74 ? 84 THR B CA 1 ATOM 4003 C C . THR B 1 84 ? 3.959 -40.052 30.593 1.00 53.34 ? 84 THR B C 1 ATOM 4004 O O . THR B 1 84 ? 2.798 -40.478 30.584 1.00 53.71 ? 84 THR B O 1 ATOM 4005 C CB . THR B 1 84 ? 5.175 -41.251 32.441 1.00 52.82 ? 84 THR B CB 1 ATOM 4006 O OG1 . THR B 1 84 ? 5.474 -40.019 33.120 1.00 52.75 ? 84 THR B OG1 1 ATOM 4007 C CG2 . THR B 1 84 ? 6.246 -42.332 32.777 1.00 52.54 ? 84 THR B CG2 1 ATOM 4008 N N . THR B 1 85 ? 4.265 -38.782 30.340 1.00 53.98 ? 85 THR B N 1 ATOM 4009 C CA . THR B 1 85 ? 3.249 -37.830 29.866 1.00 54.68 ? 85 THR B CA 1 ATOM 4010 C C . THR B 1 85 ? 3.628 -37.053 28.594 1.00 54.42 ? 85 THR B C 1 ATOM 4011 O O . THR B 1 85 ? 4.405 -36.081 28.635 1.00 54.57 ? 85 THR B O 1 ATOM 4012 C CB . THR B 1 85 ? 2.786 -36.816 30.966 1.00 54.87 ? 85 THR B CB 1 ATOM 4013 O OG1 . THR B 1 85 ? 3.922 -36.213 31.601 1.00 55.84 ? 85 THR B OG1 1 ATOM 4014 C CG2 . THR B 1 85 ? 1.945 -37.502 31.993 1.00 55.38 ? 85 THR B CG2 1 ATOM 4015 N N . PHE B 1 86 ? 3.062 -37.484 27.471 1.00 53.91 ? 86 PHE B N 1 ATOM 4016 C CA . PHE B 1 86 ? 3.090 -36.677 26.271 1.00 53.54 ? 86 PHE B CA 1 ATOM 4017 C C . PHE B 1 86 ? 1.750 -36.007 26.186 1.00 53.22 ? 86 PHE B C 1 ATOM 4018 O O . PHE B 1 86 ? 0.843 -36.531 25.529 1.00 53.14 ? 86 PHE B O 1 ATOM 4019 C CB . PHE B 1 86 ? 3.262 -37.524 25.016 1.00 53.60 ? 86 PHE B CB 1 ATOM 4020 C CG . PHE B 1 86 ? 4.363 -38.516 25.088 1.00 53.32 ? 86 PHE B CG 1 ATOM 4021 C CD1 . PHE B 1 86 ? 5.638 -38.183 24.670 1.00 52.80 ? 86 PHE B CD1 1 ATOM 4022 C CD2 . PHE B 1 86 ? 4.115 -39.805 25.536 1.00 54.36 ? 86 PHE B CD2 1 ATOM 4023 C CE1 . PHE B 1 86 ? 6.660 -39.118 24.712 1.00 53.40 ? 86 PHE B CE1 1 ATOM 4024 C CE2 . PHE B 1 86 ? 5.129 -40.752 25.586 1.00 54.78 ? 86 PHE B CE2 1 ATOM 4025 C CZ . PHE B 1 86 ? 6.408 -40.406 25.165 1.00 54.23 ? 86 PHE B CZ 1 ATOM 4026 N N . ASP B 1 87 ? 1.600 -34.871 26.861 1.00 52.81 ? 87 ASP B N 1 ATOM 4027 C CA . ASP B 1 87 ? 0.399 -34.069 26.646 1.00 52.98 ? 87 ASP B CA 1 ATOM 4028 C C . ASP B 1 87 ? 0.634 -32.550 26.447 1.00 52.61 ? 87 ASP B C 1 ATOM 4029 O O . ASP B 1 87 ? 1.784 -32.083 26.429 1.00 52.77 ? 87 ASP B O 1 ATOM 4030 C CB . ASP B 1 87 ? -0.705 -34.409 27.665 1.00 53.54 ? 87 ASP B CB 1 ATOM 4031 C CG . ASP B 1 87 ? -0.317 -34.096 29.103 1.00 54.57 ? 87 ASP B CG 1 ATOM 4032 O OD1 . ASP B 1 87 ? 0.055 -32.934 29.383 1.00 54.77 ? 87 ASP B OD1 1 ATOM 4033 O OD2 . ASP B 1 87 ? -0.429 -35.015 29.960 1.00 56.09 ? 87 ASP B OD2 1 ATOM 4034 N N . GLY B 1 88 ? -0.458 -31.800 26.270 1.00 51.97 ? 88 GLY B N 1 ATOM 4035 C CA . GLY B 1 88 ? -0.409 -30.438 25.718 1.00 50.93 ? 88 GLY B CA 1 ATOM 4036 C C . GLY B 1 88 ? 0.329 -30.446 24.383 1.00 50.05 ? 88 GLY B C 1 ATOM 4037 O O . GLY B 1 88 ? 0.103 -31.311 23.533 1.00 49.74 ? 88 GLY B O 1 ATOM 4038 N N . LYS B 1 89 ? 1.247 -29.498 24.222 1.00 49.34 ? 89 LYS B N 1 ATOM 4039 C CA . LYS B 1 89 ? 2.087 -29.410 23.015 1.00 48.21 ? 89 LYS B CA 1 ATOM 4040 C C . LYS B 1 89 ? 3.026 -30.607 22.808 1.00 47.17 ? 89 LYS B C 1 ATOM 4041 O O . LYS B 1 89 ? 3.671 -30.702 21.776 1.00 47.04 ? 89 LYS B O 1 ATOM 4042 C CB . LYS B 1 89 ? 2.859 -28.081 22.979 1.00 48.40 ? 89 LYS B CB 1 ATOM 4043 C CG . LYS B 1 89 ? 3.664 -27.754 24.238 1.00 48.98 ? 89 LYS B CG 1 ATOM 4044 C CD . LYS B 1 89 ? 3.830 -26.252 24.367 1.00 51.07 ? 89 LYS B CD 1 ATOM 4045 C CE . LYS B 1 89 ? 4.855 -25.873 25.438 1.00 52.85 ? 89 LYS B CE 1 ATOM 4046 N NZ . LYS B 1 89 ? 5.143 -24.398 25.438 1.00 51.49 ? 89 LYS B NZ 1 ATOM 4047 N N . TYR B 1 90 ? 3.064 -31.531 23.763 1.00 45.99 ? 90 TYR B N 1 ATOM 4048 C CA . TYR B 1 90 ? 3.932 -32.704 23.641 1.00 45.13 ? 90 TYR B CA 1 ATOM 4049 C C . TYR B 1 90 ? 3.254 -33.925 23.022 1.00 44.99 ? 90 TYR B C 1 ATOM 4050 O O . TYR B 1 90 ? 3.941 -34.859 22.619 1.00 44.97 ? 90 TYR B O 1 ATOM 4051 C CB . TYR B 1 90 ? 4.556 -33.091 24.999 1.00 44.62 ? 90 TYR B CB 1 ATOM 4052 C CG . TYR B 1 90 ? 5.465 -32.040 25.548 1.00 42.76 ? 90 TYR B CG 1 ATOM 4053 C CD1 . TYR B 1 90 ? 6.807 -32.014 25.198 1.00 41.67 ? 90 TYR B CD1 1 ATOM 4054 C CD2 . TYR B 1 90 ? 4.982 -31.048 26.406 1.00 41.59 ? 90 TYR B CD2 1 ATOM 4055 C CE1 . TYR B 1 90 ? 7.659 -31.020 25.686 1.00 41.05 ? 90 TYR B CE1 1 ATOM 4056 C CE2 . TYR B 1 90 ? 5.829 -30.056 26.916 1.00 40.99 ? 90 TYR B CE2 1 ATOM 4057 C CZ . TYR B 1 90 ? 7.166 -30.050 26.537 1.00 40.85 ? 90 TYR B CZ 1 ATOM 4058 O OH . TYR B 1 90 ? 8.012 -29.086 27.008 1.00 39.02 ? 90 TYR B OH 1 ATOM 4059 N N . ALA B 1 91 ? 1.924 -33.921 22.938 1.00 44.99 ? 91 ALA B N 1 ATOM 4060 C CA . ALA B 1 91 ? 1.176 -35.125 22.546 1.00 45.13 ? 91 ALA B CA 1 ATOM 4061 C C . ALA B 1 91 ? 1.748 -35.829 21.310 1.00 45.14 ? 91 ALA B C 1 ATOM 4062 O O . ALA B 1 91 ? 1.898 -37.068 21.294 1.00 44.78 ? 91 ALA B O 1 ATOM 4063 C CB . ALA B 1 91 ? -0.291 -34.808 22.363 1.00 45.17 ? 91 ALA B CB 1 ATOM 4064 N N . PHE B 1 92 ? 2.124 -35.018 20.315 1.00 45.38 ? 92 PHE B N 1 ATOM 4065 C CA . PHE B 1 92 ? 2.541 -35.495 18.986 1.00 45.29 ? 92 PHE B CA 1 ATOM 4066 C C . PHE B 1 92 ? 3.732 -36.432 19.042 1.00 45.58 ? 92 PHE B C 1 ATOM 4067 O O . PHE B 1 92 ? 3.894 -37.314 18.191 1.00 45.45 ? 92 PHE B O 1 ATOM 4068 C CB . PHE B 1 92 ? 2.831 -34.306 18.051 1.00 45.55 ? 92 PHE B CB 1 ATOM 4069 C CG . PHE B 1 92 ? 4.136 -33.604 18.330 1.00 44.05 ? 92 PHE B CG 1 ATOM 4070 C CD1 . PHE B 1 92 ? 4.187 -32.524 19.203 1.00 42.93 ? 92 PHE B CD1 1 ATOM 4071 C CD2 . PHE B 1 92 ? 5.314 -34.024 17.708 1.00 43.54 ? 92 PHE B CD2 1 ATOM 4072 C CE1 . PHE B 1 92 ? 5.398 -31.867 19.463 1.00 42.70 ? 92 PHE B CE1 1 ATOM 4073 C CE2 . PHE B 1 92 ? 6.537 -33.385 17.968 1.00 43.06 ? 92 PHE B CE2 1 ATOM 4074 C CZ . PHE B 1 92 ? 6.579 -32.308 18.849 1.00 42.78 ? 92 PHE B CZ 1 ATOM 4075 N N . LEU B 1 93 ? 4.560 -36.240 20.057 1.00 45.82 ? 93 LEU B N 1 ATOM 4076 C CA . LEU B 1 93 ? 5.750 -37.042 20.214 1.00 46.51 ? 93 LEU B CA 1 ATOM 4077 C C . LEU B 1 93 ? 5.459 -38.486 20.548 1.00 47.19 ? 93 LEU B C 1 ATOM 4078 O O . LEU B 1 93 ? 6.295 -39.357 20.306 1.00 46.84 ? 93 LEU B O 1 ATOM 4079 C CB . LEU B 1 93 ? 6.658 -36.455 21.281 1.00 46.36 ? 93 LEU B CB 1 ATOM 4080 C CG . LEU B 1 93 ? 7.612 -35.380 20.784 1.00 45.74 ? 93 LEU B CG 1 ATOM 4081 C CD1 . LEU B 1 93 ? 8.174 -34.639 21.989 1.00 45.75 ? 93 LEU B CD1 1 ATOM 4082 C CD2 . LEU B 1 93 ? 8.694 -36.023 19.962 1.00 42.53 ? 93 LEU B CD2 1 ATOM 4083 N N . LYS B 1 94 ? 4.280 -38.754 21.103 1.00 48.43 ? 94 LYS B N 1 ATOM 4084 C CA . LYS B 1 94 ? 3.965 -40.131 21.492 1.00 49.74 ? 94 LYS B CA 1 ATOM 4085 C C . LYS B 1 94 ? 4.099 -41.073 20.299 1.00 50.13 ? 94 LYS B C 1 ATOM 4086 O O . LYS B 1 94 ? 4.801 -42.112 20.380 1.00 50.15 ? 94 LYS B O 1 ATOM 4087 C CB . LYS B 1 94 ? 2.574 -40.260 22.139 1.00 49.99 ? 94 LYS B CB 1 ATOM 4088 C CG . LYS B 1 94 ? 2.255 -41.709 22.533 1.00 51.29 ? 94 LYS B CG 1 ATOM 4089 C CD . LYS B 1 94 ? 1.244 -41.832 23.667 1.00 54.40 ? 94 LYS B CD 1 ATOM 4090 C CE . LYS B 1 94 ? 0.973 -43.313 23.967 1.00 55.34 ? 94 LYS B CE 1 ATOM 4091 N NZ . LYS B 1 94 ? 0.514 -43.575 25.366 1.00 56.90 ? 94 LYS B NZ 1 ATOM 4092 N N . THR B 1 95 ? 3.447 -40.670 19.201 1.00 50.31 ? 95 THR B N 1 ATOM 4093 C CA . THR B 1 95 ? 3.354 -41.464 17.977 1.00 50.58 ? 95 THR B CA 1 ATOM 4094 C C . THR B 1 95 ? 4.335 -41.094 16.868 1.00 50.22 ? 95 THR B C 1 ATOM 4095 O O . THR B 1 95 ? 4.540 -41.892 15.942 1.00 50.83 ? 95 THR B O 1 ATOM 4096 C CB . THR B 1 95 ? 1.930 -41.396 17.375 1.00 51.11 ? 95 THR B CB 1 ATOM 4097 O OG1 . THR B 1 95 ? 1.457 -40.033 17.385 1.00 51.17 ? 95 THR B OG1 1 ATOM 4098 C CG2 . THR B 1 95 ? 0.981 -42.305 18.155 1.00 50.70 ? 95 THR B CG2 1 ATOM 4099 N N . TYR B 1 96 ? 4.934 -39.907 16.953 1.00 49.39 ? 96 TYR B N 1 ATOM 4100 C CA . TYR B 1 96 ? 5.772 -39.408 15.877 1.00 48.32 ? 96 TYR B CA 1 ATOM 4101 C C . TYR B 1 96 ? 6.624 -40.521 15.273 1.00 48.22 ? 96 TYR B C 1 ATOM 4102 O O . TYR B 1 96 ? 7.302 -41.266 15.994 1.00 47.95 ? 96 TYR B O 1 ATOM 4103 C CB . TYR B 1 96 ? 6.631 -38.204 16.309 1.00 48.07 ? 96 TYR B CB 1 ATOM 4104 C CG . TYR B 1 96 ? 7.384 -37.596 15.132 1.00 45.87 ? 96 TYR B CG 1 ATOM 4105 C CD1 . TYR B 1 96 ? 6.834 -36.561 14.393 1.00 44.23 ? 96 TYR B CD1 1 ATOM 4106 C CD2 . TYR B 1 96 ? 8.629 -38.099 14.737 1.00 44.51 ? 96 TYR B CD2 1 ATOM 4107 C CE1 . TYR B 1 96 ? 7.505 -36.032 13.308 1.00 43.17 ? 96 TYR B CE1 1 ATOM 4108 C CE2 . TYR B 1 96 ? 9.304 -37.571 13.648 1.00 43.29 ? 96 TYR B CE2 1 ATOM 4109 C CZ . TYR B 1 96 ? 8.731 -36.540 12.949 1.00 42.75 ? 96 TYR B CZ 1 ATOM 4110 O OH . TYR B 1 96 ? 9.385 -36.020 11.881 1.00 43.97 ? 96 TYR B OH 1 ATOM 4111 N N . ASN B 1 97 ? 6.573 -40.616 13.941 1.00 48.26 ? 97 ASN B N 1 ATOM 4112 C CA . ASN B 1 97 ? 7.160 -41.735 13.188 1.00 48.14 ? 97 ASN B CA 1 ATOM 4113 C C . ASN B 1 97 ? 8.181 -41.247 12.170 1.00 47.33 ? 97 ASN B C 1 ATOM 4114 O O . ASN B 1 97 ? 7.844 -40.979 11.014 1.00 47.85 ? 97 ASN B O 1 ATOM 4115 C CB . ASN B 1 97 ? 6.039 -42.546 12.503 1.00 48.56 ? 97 ASN B CB 1 ATOM 4116 C CG . ASN B 1 97 ? 6.531 -43.853 11.895 1.00 49.34 ? 97 ASN B CG 1 ATOM 4117 O OD1 . ASN B 1 97 ? 7.704 -44.234 12.041 1.00 49.68 ? 97 ASN B OD1 1 ATOM 4118 N ND2 . ASN B 1 97 ? 5.621 -44.556 11.204 1.00 50.79 ? 97 ASN B ND2 1 ATOM 4119 N N . TYR B 1 98 ? 9.430 -41.152 12.609 1.00 46.22 ? 98 TYR B N 1 ATOM 4120 C CA . TYR B 1 98 ? 10.511 -40.562 11.815 1.00 45.00 ? 98 TYR B CA 1 ATOM 4121 C C . TYR B 1 98 ? 10.694 -41.279 10.475 1.00 44.64 ? 98 TYR B C 1 ATOM 4122 O O . TYR B 1 98 ? 11.072 -42.458 10.439 1.00 44.33 ? 98 TYR B O 1 ATOM 4123 C CB . TYR B 1 98 ? 11.810 -40.536 12.631 1.00 44.21 ? 98 TYR B CB 1 ATOM 4124 C CG . TYR B 1 98 ? 12.954 -39.761 12.016 1.00 42.93 ? 98 TYR B CG 1 ATOM 4125 C CD1 . TYR B 1 98 ? 13.847 -40.384 11.133 1.00 43.25 ? 98 TYR B CD1 1 ATOM 4126 C CD2 . TYR B 1 98 ? 13.180 -38.420 12.344 1.00 40.11 ? 98 TYR B CD2 1 ATOM 4127 C CE1 . TYR B 1 98 ? 14.917 -39.682 10.568 1.00 40.97 ? 98 TYR B CE1 1 ATOM 4128 C CE2 . TYR B 1 98 ? 14.250 -37.719 11.794 1.00 38.28 ? 98 TYR B CE2 1 ATOM 4129 C CZ . TYR B 1 98 ? 15.108 -38.350 10.906 1.00 39.01 ? 98 TYR B CZ 1 ATOM 4130 O OH . TYR B 1 98 ? 16.163 -37.662 10.350 1.00 38.73 ? 98 TYR B OH 1 ATOM 4131 N N . SER B 1 99 ? 10.411 -40.549 9.387 1.00 44.07 ? 99 SER B N 1 ATOM 4132 C CA . SER B 1 99 ? 10.512 -41.088 8.022 1.00 43.48 ? 99 SER B CA 1 ATOM 4133 C C . SER B 1 99 ? 11.377 -40.294 7.042 1.00 43.26 ? 99 SER B C 1 ATOM 4134 O O . SER B 1 99 ? 11.595 -40.767 5.918 1.00 43.75 ? 99 SER B O 1 ATOM 4135 C CB . SER B 1 99 ? 9.136 -41.350 7.409 1.00 43.03 ? 99 SER B CB 1 ATOM 4136 O OG . SER B 1 99 ? 8.144 -40.570 8.020 1.00 43.32 ? 99 SER B OG 1 ATOM 4137 N N . LEU B 1 100 ? 11.863 -39.116 7.468 1.00 41.89 ? 100 LEU B N 1 ATOM 4138 C CA . LEU B 1 100 ? 12.767 -38.252 6.673 1.00 40.49 ? 100 LEU B CA 1 ATOM 4139 C C . LEU B 1 100 ? 13.841 -38.993 5.873 1.00 39.79 ? 100 LEU B C 1 ATOM 4140 O O . LEU B 1 100 ? 14.357 -40.043 6.322 1.00 40.00 ? 100 LEU B O 1 ATOM 4141 C CB . LEU B 1 100 ? 13.467 -37.220 7.570 1.00 40.27 ? 100 LEU B CB 1 ATOM 4142 C CG . LEU B 1 100 ? 12.637 -36.336 8.496 1.00 39.66 ? 100 LEU B CG 1 ATOM 4143 C CD1 . LEU B 1 100 ? 13.523 -35.264 9.099 1.00 38.00 ? 100 LEU B CD1 1 ATOM 4144 C CD2 . LEU B 1 100 ? 11.458 -35.736 7.759 1.00 41.02 ? 100 LEU B CD2 1 ATOM 4145 N N . GLY B 1 101 ? 14.178 -38.437 4.703 1.00 38.43 ? 101 GLY B N 1 ATOM 4146 C CA . GLY B 1 101 ? 15.219 -38.990 3.825 1.00 37.47 ? 101 GLY B CA 1 ATOM 4147 C C . GLY B 1 101 ? 16.574 -38.603 4.349 1.00 36.73 ? 101 GLY B C 1 ATOM 4148 O O . GLY B 1 101 ? 16.662 -38.157 5.487 1.00 36.50 ? 101 GLY B O 1 ATOM 4149 N N . ALA B 1 102 ? 17.618 -38.727 3.522 1.00 36.10 ? 102 ALA B N 1 ATOM 4150 C CA . ALA B 1 102 ? 18.982 -38.512 3.998 1.00 36.11 ? 102 ALA B CA 1 ATOM 4151 C C . ALA B 1 102 ? 19.970 -37.986 2.968 1.00 36.18 ? 102 ALA B C 1 ATOM 4152 O O . ALA B 1 102 ? 20.204 -38.610 1.932 1.00 36.82 ? 102 ALA B O 1 ATOM 4153 C CB . ALA B 1 102 ? 19.526 -39.798 4.615 1.00 36.50 ? 102 ALA B CB 1 ATOM 4154 N N . ASP B 1 103 ? 20.595 -36.862 3.294 1.00 35.93 ? 103 ASP B N 1 ATOM 4155 C CA . ASP B 1 103 ? 21.592 -36.208 2.436 1.00 35.76 ? 103 ASP B CA 1 ATOM 4156 C C . ASP B 1 103 ? 20.997 -35.510 1.221 1.00 35.11 ? 103 ASP B C 1 ATOM 4157 O O . ASP B 1 103 ? 21.476 -34.452 0.811 1.00 35.55 ? 103 ASP B O 1 ATOM 4158 C CB . ASP B 1 103 ? 22.682 -37.193 1.992 1.00 36.21 ? 103 ASP B CB 1 ATOM 4159 C CG . ASP B 1 103 ? 23.418 -37.821 3.176 1.00 38.19 ? 103 ASP B CG 1 ATOM 4160 O OD1 . ASP B 1 103 ? 24.236 -37.101 3.819 1.00 37.72 ? 103 ASP B OD1 1 ATOM 4161 O OD2 . ASP B 1 103 ? 23.164 -39.033 3.447 1.00 38.16 ? 103 ASP B OD2 1 ATOM 4162 N N . ASP B 1 104 ? 19.953 -36.109 0.655 1.00 34.30 ? 104 ASP B N 1 ATOM 4163 C CA . ASP B 1 104 ? 19.459 -35.729 -0.655 1.00 33.51 ? 104 ASP B CA 1 ATOM 4164 C C . ASP B 1 104 ? 18.761 -34.374 -0.545 1.00 32.07 ? 104 ASP B C 1 ATOM 4165 O O . ASP B 1 104 ? 18.433 -33.939 0.548 1.00 31.66 ? 104 ASP B O 1 ATOM 4166 C CB . ASP B 1 104 ? 18.533 -36.822 -1.241 1.00 34.25 ? 104 ASP B CB 1 ATOM 4167 C CG . ASP B 1 104 ? 19.276 -38.172 -1.569 1.00 36.24 ? 104 ASP B CG 1 ATOM 4168 O OD1 . ASP B 1 104 ? 20.537 -38.227 -1.552 1.00 38.53 ? 104 ASP B OD1 1 ATOM 4169 O OD2 . ASP B 1 104 ? 18.586 -39.186 -1.862 1.00 36.01 ? 104 ASP B OD2 1 ATOM 4170 N N . LEU B 1 105 ? 18.638 -33.676 -1.668 1.00 30.28 ? 105 LEU B N 1 ATOM 4171 C CA . LEU B 1 105 ? 17.767 -32.519 -1.784 1.00 29.12 ? 105 LEU B CA 1 ATOM 4172 C C . LEU B 1 105 ? 16.305 -32.947 -1.504 1.00 28.56 ? 105 LEU B C 1 ATOM 4173 O O . LEU B 1 105 ? 15.920 -34.067 -1.808 1.00 29.71 ? 105 LEU B O 1 ATOM 4174 C CB . LEU B 1 105 ? 17.886 -32.011 -3.217 1.00 28.83 ? 105 LEU B CB 1 ATOM 4175 C CG . LEU B 1 105 ? 18.481 -30.703 -3.707 1.00 28.22 ? 105 LEU B CG 1 ATOM 4176 C CD1 . LEU B 1 105 ? 19.608 -30.222 -2.843 1.00 28.19 ? 105 LEU B CD1 1 ATOM 4177 C CD2 . LEU B 1 105 ? 18.895 -30.782 -5.193 1.00 26.67 ? 105 LEU B CD2 1 ATOM 4178 N N . THR B 1 106 ? 15.482 -32.092 -0.930 1.00 27.46 ? 106 THR B N 1 ATOM 4179 C CA . THR B 1 106 ? 14.050 -32.407 -0.806 1.00 26.94 ? 106 THR B CA 1 ATOM 4180 C C . THR B 1 106 ? 13.221 -31.839 -1.985 1.00 27.16 ? 106 THR B C 1 ATOM 4181 O O . THR B 1 106 ? 13.672 -30.922 -2.663 1.00 27.61 ? 106 THR B O 1 ATOM 4182 C CB . THR B 1 106 ? 13.501 -31.801 0.450 1.00 26.68 ? 106 THR B CB 1 ATOM 4183 O OG1 . THR B 1 106 ? 13.648 -30.378 0.363 1.00 27.03 ? 106 THR B OG1 1 ATOM 4184 C CG2 . THR B 1 106 ? 14.227 -32.336 1.665 1.00 25.56 ? 106 THR B CG2 1 ATOM 4185 N N . PRO B 1 107 ? 12.018 -32.374 -2.262 1.00 27.33 ? 107 PRO B N 1 ATOM 4186 C CA . PRO B 1 107 ? 11.252 -31.710 -3.323 1.00 26.90 ? 107 PRO B CA 1 ATOM 4187 C C . PRO B 1 107 ? 11.256 -30.187 -3.179 1.00 26.37 ? 107 PRO B C 1 ATOM 4188 O O . PRO B 1 107 ? 11.495 -29.472 -4.151 1.00 26.85 ? 107 PRO B O 1 ATOM 4189 C CB . PRO B 1 107 ? 9.836 -32.272 -3.133 1.00 27.71 ? 107 PRO B CB 1 ATOM 4190 C CG . PRO B 1 107 ? 10.057 -33.666 -2.505 1.00 27.99 ? 107 PRO B CG 1 ATOM 4191 C CD . PRO B 1 107 ? 11.520 -33.743 -2.039 1.00 27.64 ? 107 PRO B CD 1 ATOM 4192 N N . PHE B 1 108 ? 11.025 -29.694 -1.972 1.00 24.91 ? 108 PHE B N 1 ATOM 4193 C CA . PHE B 1 108 ? 11.063 -28.255 -1.704 1.00 23.71 ? 108 PHE B CA 1 ATOM 4194 C C . PHE B 1 108 ? 12.448 -27.616 -2.046 1.00 22.50 ? 108 PHE B C 1 ATOM 4195 O O . PHE B 1 108 ? 12.551 -26.575 -2.685 1.00 21.52 ? 108 PHE B O 1 ATOM 4196 C CB . PHE B 1 108 ? 10.652 -28.001 -0.235 1.00 23.46 ? 108 PHE B CB 1 ATOM 4197 C CG . PHE B 1 108 ? 10.791 -26.561 0.206 1.00 23.51 ? 108 PHE B CG 1 ATOM 4198 C CD1 . PHE B 1 108 ? 9.779 -25.649 -0.051 1.00 21.79 ? 108 PHE B CD1 1 ATOM 4199 C CD2 . PHE B 1 108 ? 11.929 -26.128 0.866 1.00 24.10 ? 108 PHE B CD2 1 ATOM 4200 C CE1 . PHE B 1 108 ? 9.886 -24.364 0.319 1.00 22.29 ? 108 PHE B CE1 1 ATOM 4201 C CE2 . PHE B 1 108 ? 12.049 -24.807 1.254 1.00 25.79 ? 108 PHE B CE2 1 ATOM 4202 C CZ . PHE B 1 108 ? 11.018 -23.919 0.970 1.00 25.11 ? 108 PHE B CZ 1 ATOM 4203 N N . GLY B 1 109 ? 13.512 -28.251 -1.606 1.00 22.17 ? 109 GLY B N 1 ATOM 4204 C CA . GLY B 1 109 ? 14.842 -27.771 -1.932 1.00 21.74 ? 109 GLY B CA 1 ATOM 4205 C C . GLY B 1 109 ? 15.057 -27.719 -3.430 1.00 20.96 ? 109 GLY B C 1 ATOM 4206 O O . GLY B 1 109 ? 15.717 -26.826 -3.946 1.00 21.58 ? 109 GLY B O 1 ATOM 4207 N N . GLU B 1 110 ? 14.506 -28.699 -4.123 1.00 20.69 ? 110 GLU B N 1 ATOM 4208 C CA . GLU B 1 110 ? 14.552 -28.743 -5.580 1.00 19.90 ? 110 GLU B CA 1 ATOM 4209 C C . GLU B 1 110 ? 13.882 -27.521 -6.203 1.00 18.81 ? 110 GLU B C 1 ATOM 4210 O O . GLU B 1 110 ? 14.485 -26.821 -7.044 1.00 18.19 ? 110 GLU B O 1 ATOM 4211 C CB . GLU B 1 110 ? 13.910 -30.048 -6.076 1.00 19.84 ? 110 GLU B CB 1 ATOM 4212 C CG . GLU B 1 110 ? 14.718 -31.290 -5.706 1.00 23.07 ? 110 GLU B CG 1 ATOM 4213 C CD . GLU B 1 110 ? 14.144 -32.604 -6.266 1.00 24.59 ? 110 GLU B CD 1 ATOM 4214 O OE1 . GLU B 1 110 ? 13.234 -32.579 -7.111 1.00 26.32 ? 110 GLU B OE1 1 ATOM 4215 O OE2 . GLU B 1 110 ? 14.628 -33.680 -5.862 1.00 27.82 ? 110 GLU B OE2 1 ATOM 4216 N N . GLN B 1 111 ? 12.641 -27.270 -5.778 1.00 18.26 ? 111 GLN B N 1 ATOM 4217 C CA . GLN B 1 111 ? 11.866 -26.145 -6.255 1.00 18.78 ? 111 GLN B CA 1 ATOM 4218 C C . GLN B 1 111 ? 12.535 -24.778 -5.964 1.00 19.26 ? 111 GLN B C 1 ATOM 4219 O O . GLN B 1 111 ? 12.399 -23.825 -6.742 1.00 19.11 ? 111 GLN B O 1 ATOM 4220 C CB . GLN B 1 111 ? 10.437 -26.166 -5.693 1.00 18.90 ? 111 GLN B CB 1 ATOM 4221 C CG . GLN B 1 111 ? 9.560 -25.007 -6.283 1.00 18.71 ? 111 GLN B CG 1 ATOM 4222 C CD . GLN B 1 111 ? 9.358 -25.217 -7.780 1.00 20.72 ? 111 GLN B CD 1 ATOM 4223 O OE1 . GLN B 1 111 ? 8.961 -26.304 -8.205 1.00 21.91 ? 111 GLN B OE1 1 ATOM 4224 N NE2 . GLN B 1 111 ? 9.664 -24.204 -8.582 1.00 18.83 ? 111 GLN B NE2 1 ATOM 4225 N N . GLU B 1 112 ? 13.214 -24.688 -4.832 1.00 19.59 ? 112 GLU B N 1 ATOM 4226 C CA . GLU B 1 112 ? 13.966 -23.483 -4.472 1.00 20.78 ? 112 GLU B CA 1 ATOM 4227 C C . GLU B 1 112 ? 14.963 -23.148 -5.553 1.00 20.77 ? 112 GLU B C 1 ATOM 4228 O O . GLU B 1 112 ? 15.110 -21.996 -5.927 1.00 21.07 ? 112 GLU B O 1 ATOM 4229 C CB . GLU B 1 112 ? 14.728 -23.677 -3.136 1.00 20.56 ? 112 GLU B CB 1 ATOM 4230 C CG . GLU B 1 112 ? 13.994 -23.201 -1.886 1.00 22.22 ? 112 GLU B CG 1 ATOM 4231 C CD . GLU B 1 112 ? 14.834 -23.405 -0.590 1.00 24.69 ? 112 GLU B CD 1 ATOM 4232 O OE1 . GLU B 1 112 ? 15.678 -24.348 -0.590 1.00 26.09 ? 112 GLU B OE1 1 ATOM 4233 O OE2 . GLU B 1 112 ? 14.633 -22.652 0.417 1.00 22.74 ? 112 GLU B OE2 1 ATOM 4234 N N . LEU B 1 113 ? 15.666 -24.143 -6.072 1.00 20.83 ? 113 LEU B N 1 ATOM 4235 C CA . LEU B 1 113 ? 16.715 -23.793 -7.030 1.00 21.05 ? 113 LEU B CA 1 ATOM 4236 C C . LEU B 1 113 ? 16.114 -23.559 -8.423 1.00 21.45 ? 113 LEU B C 1 ATOM 4237 O O . LEU B 1 113 ? 16.754 -22.916 -9.273 1.00 21.83 ? 113 LEU B O 1 ATOM 4238 C CB . LEU B 1 113 ? 17.828 -24.841 -7.045 1.00 20.66 ? 113 LEU B CB 1 ATOM 4239 C CG . LEU B 1 113 ? 18.976 -24.722 -6.005 1.00 21.59 ? 113 LEU B CG 1 ATOM 4240 C CD1 . LEU B 1 113 ? 20.225 -23.887 -6.495 1.00 21.46 ? 113 LEU B CD1 1 ATOM 4241 C CD2 . LEU B 1 113 ? 18.492 -24.229 -4.680 1.00 20.08 ? 113 LEU B CD2 1 ATOM 4242 N N . VAL B 1 114 ? 14.890 -24.075 -8.638 1.00 21.07 ? 114 VAL B N 1 ATOM 4243 C CA . VAL B 1 114 ? 14.164 -23.875 -9.886 1.00 19.68 ? 114 VAL B CA 1 ATOM 4244 C C . VAL B 1 114 ? 13.807 -22.415 -9.819 1.00 19.92 ? 114 VAL B C 1 ATOM 4245 O O . VAL B 1 114 ? 14.089 -21.655 -10.760 1.00 19.66 ? 114 VAL B O 1 ATOM 4246 C CB . VAL B 1 114 ? 12.873 -24.729 -9.985 1.00 19.72 ? 114 VAL B CB 1 ATOM 4247 C CG1 . VAL B 1 114 ? 11.910 -24.159 -11.059 1.00 18.35 ? 114 VAL B CG1 1 ATOM 4248 C CG2 . VAL B 1 114 ? 13.207 -26.169 -10.292 1.00 17.87 ? 114 VAL B CG2 1 ATOM 4249 N N . ASN B 1 115 ? 13.228 -22.014 -8.682 1.00 18.76 ? 115 ASN B N 1 ATOM 4250 C CA . ASN B 1 115 ? 12.829 -20.633 -8.510 1.00 18.10 ? 115 ASN B CA 1 ATOM 4251 C C . ASN B 1 115 ? 14.020 -19.626 -8.617 1.00 17.62 ? 115 ASN B C 1 ATOM 4252 O O . ASN B 1 115 ? 13.880 -18.547 -9.196 1.00 18.04 ? 115 ASN B O 1 ATOM 4253 C CB . ASN B 1 115 ? 12.071 -20.457 -7.195 1.00 17.75 ? 115 ASN B CB 1 ATOM 4254 C CG . ASN B 1 115 ? 10.727 -21.183 -7.177 1.00 19.13 ? 115 ASN B CG 1 ATOM 4255 O OD1 . ASN B 1 115 ? 10.272 -21.772 -8.175 1.00 18.55 ? 115 ASN B OD1 1 ATOM 4256 N ND2 . ASN B 1 115 ? 10.083 -21.139 -6.034 1.00 14.89 ? 115 ASN B ND2 1 ATOM 4257 N N . SER B 1 116 ? 15.164 -19.960 -8.023 1.00 17.25 ? 116 SER B N 1 ATOM 4258 C CA . SER B 1 116 ? 16.376 -19.151 -8.141 1.00 16.63 ? 116 SER B CA 1 ATOM 4259 C C . SER B 1 116 ? 16.753 -18.986 -9.633 1.00 16.69 ? 116 SER B C 1 ATOM 4260 O O . SER B 1 116 ? 17.182 -17.911 -10.027 1.00 16.41 ? 116 SER B O 1 ATOM 4261 C CB . SER B 1 116 ? 17.500 -19.809 -7.347 1.00 16.51 ? 116 SER B CB 1 ATOM 4262 O OG . SER B 1 116 ? 18.788 -19.210 -7.513 1.00 16.44 ? 116 SER B OG 1 ATOM 4263 N N . GLY B 1 117 ? 16.578 -20.054 -10.444 1.00 16.70 ? 117 GLY B N 1 ATOM 4264 C CA . GLY B 1 117 ? 16.843 -20.037 -11.891 1.00 15.13 ? 117 GLY B CA 1 ATOM 4265 C C . GLY B 1 117 ? 15.941 -19.063 -12.642 1.00 14.90 ? 117 GLY B C 1 ATOM 4266 O O . GLY B 1 117 ? 16.393 -18.247 -13.450 1.00 14.34 ? 117 GLY B O 1 ATOM 4267 N N . ILE B 1 118 ? 14.657 -19.130 -12.345 1.00 14.39 ? 118 ILE B N 1 ATOM 4268 C CA . ILE B 1 118 ? 13.714 -18.222 -12.911 1.00 14.33 ? 118 ILE B CA 1 ATOM 4269 C C . ILE B 1 118 ? 14.125 -16.790 -12.551 1.00 14.80 ? 118 ILE B C 1 ATOM 4270 O O . ILE B 1 118 ? 14.261 -15.915 -13.419 1.00 14.04 ? 118 ILE B O 1 ATOM 4271 C CB . ILE B 1 118 ? 12.268 -18.558 -12.420 1.00 13.95 ? 118 ILE B CB 1 ATOM 4272 C CG1 . ILE B 1 118 ? 11.926 -20.002 -12.804 1.00 12.99 ? 118 ILE B CG1 1 ATOM 4273 C CG2 . ILE B 1 118 ? 11.245 -17.510 -13.013 1.00 13.67 ? 118 ILE B CG2 1 ATOM 4274 C CD1 . ILE B 1 118 ? 10.556 -20.531 -12.256 1.00 9.54 ? 118 ILE B CD1 1 ATOM 4275 N N . LYS B 1 119 ? 14.348 -16.569 -11.261 1.00 14.90 ? 119 LYS B N 1 ATOM 4276 C CA . LYS B 1 119 ? 14.624 -15.234 -10.771 1.00 15.17 ? 119 LYS B CA 1 ATOM 4277 C C . LYS B 1 119 ? 15.891 -14.720 -11.427 1.00 15.28 ? 119 LYS B C 1 ATOM 4278 O O . LYS B 1 119 ? 15.940 -13.567 -11.886 1.00 14.96 ? 119 LYS B O 1 ATOM 4279 C CB . LYS B 1 119 ? 14.660 -15.193 -9.235 1.00 14.83 ? 119 LYS B CB 1 ATOM 4280 C CG . LYS B 1 119 ? 14.811 -13.792 -8.664 1.00 16.03 ? 119 LYS B CG 1 ATOM 4281 C CD . LYS B 1 119 ? 14.191 -13.616 -7.265 1.00 17.16 ? 119 LYS B CD 1 ATOM 4282 C CE . LYS B 1 119 ? 14.323 -12.159 -6.873 1.00 17.13 ? 119 LYS B CE 1 ATOM 4283 N NZ . LYS B 1 119 ? 14.431 -11.979 -5.423 1.00 15.66 ? 119 LYS B NZ 1 ATOM 4284 N N . PHE B 1 120 ? 16.912 -15.565 -11.523 1.00 15.33 ? 120 PHE B N 1 ATOM 4285 C CA . PHE B 1 120 ? 18.163 -15.062 -12.145 1.00 16.36 ? 120 PHE B CA 1 ATOM 4286 C C . PHE B 1 120 ? 17.910 -14.685 -13.599 1.00 16.57 ? 120 PHE B C 1 ATOM 4287 O O . PHE B 1 120 ? 18.389 -13.651 -14.041 1.00 15.27 ? 120 PHE B O 1 ATOM 4288 C CB . PHE B 1 120 ? 19.311 -16.058 -12.035 1.00 15.13 ? 120 PHE B CB 1 ATOM 4289 C CG . PHE B 1 120 ? 20.635 -15.538 -12.545 1.00 15.05 ? 120 PHE B CG 1 ATOM 4290 C CD1 . PHE B 1 120 ? 21.381 -14.639 -11.798 1.00 15.49 ? 120 PHE B CD1 1 ATOM 4291 C CD2 . PHE B 1 120 ? 21.172 -16.016 -13.727 1.00 14.81 ? 120 PHE B CD2 1 ATOM 4292 C CE1 . PHE B 1 120 ? 22.623 -14.197 -12.237 1.00 13.81 ? 120 PHE B CE1 1 ATOM 4293 C CE2 . PHE B 1 120 ? 22.405 -15.584 -14.174 1.00 16.54 ? 120 PHE B CE2 1 ATOM 4294 C CZ . PHE B 1 120 ? 23.127 -14.646 -13.427 1.00 16.09 ? 120 PHE B CZ 1 ATOM 4295 N N . TYR B 1 121 ? 17.094 -15.508 -14.290 1.00 17.32 ? 121 TYR B N 1 ATOM 4296 C CA . TYR B 1 121 ? 16.831 -15.311 -15.720 1.00 18.03 ? 121 TYR B CA 1 ATOM 4297 C C . TYR B 1 121 ? 16.272 -13.913 -15.935 1.00 18.61 ? 121 TYR B C 1 ATOM 4298 O O . TYR B 1 121 ? 16.756 -13.169 -16.790 1.00 19.27 ? 121 TYR B O 1 ATOM 4299 C CB . TYR B 1 121 ? 15.869 -16.349 -16.348 1.00 17.88 ? 121 TYR B CB 1 ATOM 4300 C CG . TYR B 1 121 ? 15.676 -16.038 -17.829 1.00 18.08 ? 121 TYR B CG 1 ATOM 4301 C CD1 . TYR B 1 121 ? 14.618 -15.237 -18.296 1.00 17.13 ? 121 TYR B CD1 1 ATOM 4302 C CD2 . TYR B 1 121 ? 16.629 -16.445 -18.747 1.00 16.93 ? 121 TYR B CD2 1 ATOM 4303 C CE1 . TYR B 1 121 ? 14.501 -14.925 -19.669 1.00 13.78 ? 121 TYR B CE1 1 ATOM 4304 C CE2 . TYR B 1 121 ? 16.521 -16.119 -20.055 1.00 16.19 ? 121 TYR B CE2 1 ATOM 4305 C CZ . TYR B 1 121 ? 15.486 -15.368 -20.506 1.00 13.83 ? 121 TYR B CZ 1 ATOM 4306 O OH . TYR B 1 121 ? 15.505 -15.113 -21.820 1.00 15.68 ? 121 TYR B OH 1 ATOM 4307 N N . GLN B 1 122 ? 15.277 -13.586 -15.125 1.00 18.31 ? 122 GLN B N 1 ATOM 4308 C CA . GLN B 1 122 ? 14.488 -12.390 -15.254 1.00 19.64 ? 122 GLN B CA 1 ATOM 4309 C C . GLN B 1 122 ? 15.238 -11.093 -14.902 1.00 20.44 ? 122 GLN B C 1 ATOM 4310 O O . GLN B 1 122 ? 15.111 -10.095 -15.611 1.00 20.48 ? 122 GLN B O 1 ATOM 4311 C CB . GLN B 1 122 ? 13.216 -12.549 -14.399 1.00 20.17 ? 122 GLN B CB 1 ATOM 4312 C CG . GLN B 1 122 ? 12.532 -13.860 -14.708 1.00 23.48 ? 122 GLN B CG 1 ATOM 4313 C CD . GLN B 1 122 ? 11.026 -13.841 -14.478 1.00 29.91 ? 122 GLN B CD 1 ATOM 4314 O OE1 . GLN B 1 122 ? 10.554 -13.665 -13.343 1.00 32.03 ? 122 GLN B OE1 1 ATOM 4315 N NE2 . GLN B 1 122 ? 10.255 -14.067 -15.560 1.00 30.81 ? 122 GLN B NE2 1 ATOM 4316 N N . ARG B 1 123 ? 15.967 -11.101 -13.777 1.00 20.11 ? 123 ARG B N 1 ATOM 4317 C CA . ARG B 1 123 ? 16.616 -9.944 -13.260 1.00 19.86 ? 123 ARG B CA 1 ATOM 4318 C C . ARG B 1 123 ? 17.633 -9.476 -14.293 1.00 20.24 ? 123 ARG B C 1 ATOM 4319 O O . ARG B 1 123 ? 17.919 -8.274 -14.433 1.00 20.56 ? 123 ARG B O 1 ATOM 4320 C CB . ARG B 1 123 ? 17.325 -10.316 -11.952 1.00 19.85 ? 123 ARG B CB 1 ATOM 4321 C CG . ARG B 1 123 ? 18.027 -9.141 -11.332 1.00 20.31 ? 123 ARG B CG 1 ATOM 4322 C CD . ARG B 1 123 ? 18.575 -9.410 -9.899 1.00 22.72 ? 123 ARG B CD 1 ATOM 4323 N NE . ARG B 1 123 ? 19.462 -8.303 -9.551 1.00 22.07 ? 123 ARG B NE 1 ATOM 4324 C CZ . ARG B 1 123 ? 19.075 -7.175 -8.952 1.00 23.06 ? 123 ARG B CZ 1 ATOM 4325 N NH1 . ARG B 1 123 ? 17.814 -7.010 -8.571 1.00 20.73 ? 123 ARG B NH1 1 ATOM 4326 N NH2 . ARG B 1 123 ? 19.964 -6.210 -8.725 1.00 24.42 ? 123 ARG B NH2 1 ATOM 4327 N N . TYR B 1 124 ? 18.198 -10.420 -15.012 1.00 19.86 ? 124 TYR B N 1 ATOM 4328 C CA . TYR B 1 124 ? 19.217 -10.051 -15.987 1.00 20.19 ? 124 TYR B CA 1 ATOM 4329 C C . TYR B 1 124 ? 18.784 -10.411 -17.417 1.00 20.46 ? 124 TYR B C 1 ATOM 4330 O O . TYR B 1 124 ? 19.611 -10.559 -18.321 1.00 19.07 ? 124 TYR B O 1 ATOM 4331 C CB . TYR B 1 124 ? 20.544 -10.663 -15.597 1.00 20.03 ? 124 TYR B CB 1 ATOM 4332 C CG . TYR B 1 124 ? 20.960 -10.242 -14.208 1.00 19.84 ? 124 TYR B CG 1 ATOM 4333 C CD1 . TYR B 1 124 ? 21.410 -8.944 -13.949 1.00 19.01 ? 124 TYR B CD1 1 ATOM 4334 C CD2 . TYR B 1 124 ? 20.892 -11.145 -13.152 1.00 19.64 ? 124 TYR B CD2 1 ATOM 4335 C CE1 . TYR B 1 124 ? 21.771 -8.542 -12.650 1.00 18.76 ? 124 TYR B CE1 1 ATOM 4336 C CE2 . TYR B 1 124 ? 21.255 -10.787 -11.889 1.00 19.76 ? 124 TYR B CE2 1 ATOM 4337 C CZ . TYR B 1 124 ? 21.684 -9.481 -11.622 1.00 19.64 ? 124 TYR B CZ 1 ATOM 4338 O OH . TYR B 1 124 ? 22.041 -9.166 -10.322 1.00 18.02 ? 124 TYR B OH 1 ATOM 4339 N N . GLU B 1 125 ? 17.457 -10.490 -17.583 1.00 20.32 ? 125 GLU B N 1 ATOM 4340 C CA . GLU B 1 125 ? 16.808 -10.751 -18.875 1.00 21.26 ? 125 GLU B CA 1 ATOM 4341 C C . GLU B 1 125 ? 17.471 -10.123 -20.116 1.00 21.22 ? 125 GLU B C 1 ATOM 4342 O O . GLU B 1 125 ? 17.614 -10.770 -21.175 1.00 21.03 ? 125 GLU B O 1 ATOM 4343 C CB . GLU B 1 125 ? 15.353 -10.306 -18.816 1.00 21.11 ? 125 GLU B CB 1 ATOM 4344 C CG . GLU B 1 125 ? 14.527 -10.901 -19.903 1.00 21.30 ? 125 GLU B CG 1 ATOM 4345 C CD . GLU B 1 125 ? 14.592 -10.130 -21.186 1.00 20.04 ? 125 GLU B CD 1 ATOM 4346 O OE1 . GLU B 1 125 ? 14.681 -8.885 -21.155 1.00 17.94 ? 125 GLU B OE1 1 ATOM 4347 O OE2 . GLU B 1 125 ? 14.584 -10.803 -22.234 1.00 20.97 ? 125 GLU B OE2 1 ATOM 4348 N N . SER B 1 126 ? 17.846 -8.855 -20.003 1.00 20.35 ? 126 SER B N 1 ATOM 4349 C CA . SER B 1 126 ? 18.354 -8.212 -21.179 1.00 20.80 ? 126 SER B CA 1 ATOM 4350 C C . SER B 1 126 ? 19.750 -8.761 -21.518 1.00 19.39 ? 126 SER B C 1 ATOM 4351 O O . SER B 1 126 ? 20.277 -8.447 -22.574 1.00 19.67 ? 126 SER B O 1 ATOM 4352 C CB . SER B 1 126 ? 18.251 -6.675 -21.112 1.00 20.85 ? 126 SER B CB 1 ATOM 4353 O OG . SER B 1 126 ? 19.401 -6.184 -20.509 1.00 23.85 ? 126 SER B OG 1 ATOM 4354 N N . LEU B 1 127 ? 20.279 -9.657 -20.681 1.00 18.45 ? 127 LEU B N 1 ATOM 4355 C CA . LEU B 1 127 ? 21.509 -10.409 -21.003 1.00 17.05 ? 127 LEU B CA 1 ATOM 4356 C C . LEU B 1 127 ? 21.335 -11.908 -21.136 1.00 17.97 ? 127 LEU B C 1 ATOM 4357 O O . LEU B 1 127 ? 22.101 -12.558 -21.889 1.00 18.01 ? 127 LEU B O 1 ATOM 4358 C CB . LEU B 1 127 ? 22.571 -10.175 -19.959 1.00 16.75 ? 127 LEU B CB 1 ATOM 4359 C CG . LEU B 1 127 ? 22.988 -8.742 -19.726 1.00 13.48 ? 127 LEU B CG 1 ATOM 4360 C CD1 . LEU B 1 127 ? 23.795 -8.630 -18.439 1.00 8.77 ? 127 LEU B CD1 1 ATOM 4361 C CD2 . LEU B 1 127 ? 23.752 -8.342 -20.915 1.00 14.02 ? 127 LEU B CD2 1 ATOM 4362 N N . THR B 1 128 ? 20.354 -12.452 -20.394 1.00 18.20 ? 128 THR B N 1 ATOM 4363 C CA . THR B 1 128 ? 20.122 -13.875 -20.277 1.00 18.11 ? 128 THR B CA 1 ATOM 4364 C C . THR B 1 128 ? 19.354 -14.357 -21.533 1.00 19.43 ? 128 THR B C 1 ATOM 4365 O O . THR B 1 128 ? 19.117 -15.541 -21.740 1.00 19.52 ? 128 THR B O 1 ATOM 4366 C CB . THR B 1 128 ? 19.381 -14.253 -18.914 1.00 18.43 ? 128 THR B CB 1 ATOM 4367 O OG1 . THR B 1 128 ? 18.122 -13.567 -18.795 1.00 18.26 ? 128 THR B OG1 1 ATOM 4368 C CG2 . THR B 1 128 ? 20.188 -13.893 -17.686 1.00 17.86 ? 128 THR B CG2 1 ATOM 4369 N N . ARG B 1 129 ? 18.966 -13.422 -22.380 1.00 20.82 ? 129 ARG B N 1 ATOM 4370 C CA . ARG B 1 129 ? 18.182 -13.757 -23.535 1.00 21.83 ? 129 ARG B CA 1 ATOM 4371 C C . ARG B 1 129 ? 19.025 -14.308 -24.643 1.00 22.34 ? 129 ARG B C 1 ATOM 4372 O O . ARG B 1 129 ? 18.510 -15.057 -25.466 1.00 22.00 ? 129 ARG B O 1 ATOM 4373 C CB . ARG B 1 129 ? 17.386 -12.569 -24.033 1.00 22.46 ? 129 ARG B CB 1 ATOM 4374 C CG . ARG B 1 129 ? 18.159 -11.397 -24.660 1.00 23.00 ? 129 ARG B CG 1 ATOM 4375 C CD . ARG B 1 129 ? 17.312 -10.208 -24.247 1.00 24.72 ? 129 ARG B CD 1 ATOM 4376 N NE . ARG B 1 129 ? 17.227 -9.160 -25.229 1.00 25.43 ? 129 ARG B NE 1 ATOM 4377 C CZ . ARG B 1 129 ? 16.436 -8.088 -25.129 1.00 25.68 ? 129 ARG B CZ 1 ATOM 4378 N NH1 . ARG B 1 129 ? 15.627 -7.872 -24.086 1.00 25.18 ? 129 ARG B NH1 1 ATOM 4379 N NH2 . ARG B 1 129 ? 16.451 -7.216 -26.108 1.00 26.43 ? 129 ARG B NH2 1 ATOM 4380 N N . ASN B 1 130 ? 20.313 -13.977 -24.650 1.00 22.61 ? 130 ASN B N 1 ATOM 4381 C CA . ASN B 1 130 ? 21.175 -14.387 -25.763 1.00 23.27 ? 130 ASN B CA 1 ATOM 4382 C C . ASN B 1 130 ? 22.613 -14.673 -25.363 1.00 23.26 ? 130 ASN B C 1 ATOM 4383 O O . ASN B 1 130 ? 23.515 -14.774 -26.207 1.00 24.25 ? 130 ASN B O 1 ATOM 4384 C CB . ASN B 1 130 ? 21.160 -13.319 -26.856 1.00 23.80 ? 130 ASN B CB 1 ATOM 4385 C CG . ASN B 1 130 ? 21.808 -11.990 -26.416 1.00 25.34 ? 130 ASN B CG 1 ATOM 4386 O OD1 . ASN B 1 130 ? 22.186 -11.795 -25.256 1.00 26.90 ? 130 ASN B OD1 1 ATOM 4387 N ND2 . ASN B 1 130 ? 21.901 -11.065 -27.344 1.00 24.79 ? 130 ASN B ND2 1 ATOM 4388 N N . ILE B 1 131 ? 22.841 -14.784 -24.068 1.00 23.21 ? 131 ILE B N 1 ATOM 4389 C CA . ILE B 1 131 ? 24.148 -15.202 -23.579 1.00 22.29 ? 131 ILE B CA 1 ATOM 4390 C C . ILE B 1 131 ? 24.002 -16.405 -22.690 1.00 22.14 ? 131 ILE B C 1 ATOM 4391 O O . ILE B 1 131 ? 23.255 -16.366 -21.708 1.00 22.22 ? 131 ILE B O 1 ATOM 4392 C CB . ILE B 1 131 ? 24.862 -14.089 -22.823 1.00 21.97 ? 131 ILE B CB 1 ATOM 4393 C CG1 . ILE B 1 131 ? 25.336 -13.030 -23.833 1.00 22.02 ? 131 ILE B CG1 1 ATOM 4394 C CG2 . ILE B 1 131 ? 26.072 -14.683 -22.100 1.00 21.56 ? 131 ILE B CG2 1 ATOM 4395 C CD1 . ILE B 1 131 ? 25.318 -11.653 -23.341 1.00 21.08 ? 131 ILE B CD1 1 ATOM 4396 N N . VAL B 1 132 ? 24.727 -17.460 -23.045 1.00 21.82 ? 132 VAL B N 1 ATOM 4397 C CA . VAL B 1 132 ? 24.775 -18.685 -22.256 1.00 21.16 ? 132 VAL B CA 1 ATOM 4398 C C . VAL B 1 132 ? 25.817 -18.530 -21.135 1.00 20.64 ? 132 VAL B C 1 ATOM 4399 O O . VAL B 1 132 ? 27.024 -18.381 -21.411 1.00 20.50 ? 132 VAL B O 1 ATOM 4400 C CB . VAL B 1 132 ? 25.041 -19.899 -23.182 1.00 21.13 ? 132 VAL B CB 1 ATOM 4401 C CG1 . VAL B 1 132 ? 25.116 -21.195 -22.415 1.00 20.89 ? 132 VAL B CG1 1 ATOM 4402 C CG2 . VAL B 1 132 ? 23.891 -19.994 -24.192 1.00 21.48 ? 132 VAL B CG2 1 ATOM 4403 N N . PRO B 1 133 ? 25.344 -18.527 -19.869 1.00 19.70 ? 133 PRO B N 1 ATOM 4404 C CA . PRO B 1 133 ? 26.238 -18.386 -18.720 1.00 19.41 ? 133 PRO B CA 1 ATOM 4405 C C . PRO B 1 133 ? 27.267 -19.521 -18.609 1.00 19.39 ? 133 PRO B C 1 ATOM 4406 O O . PRO B 1 133 ? 26.948 -20.678 -18.933 1.00 19.31 ? 133 PRO B O 1 ATOM 4407 C CB . PRO B 1 133 ? 25.278 -18.405 -17.520 1.00 18.89 ? 133 PRO B CB 1 ATOM 4408 C CG . PRO B 1 133 ? 23.918 -18.088 -18.086 1.00 19.34 ? 133 PRO B CG 1 ATOM 4409 C CD . PRO B 1 133 ? 23.940 -18.711 -19.441 1.00 19.87 ? 133 PRO B CD 1 ATOM 4410 N N . PHE B 1 134 ? 28.490 -19.200 -18.175 1.00 17.96 ? 134 PHE B N 1 ATOM 4411 C CA . PHE B 1 134 ? 29.456 -20.253 -17.886 1.00 17.49 ? 134 PHE B CA 1 ATOM 4412 C C . PHE B 1 134 ? 29.272 -20.730 -16.451 1.00 16.42 ? 134 PHE B C 1 ATOM 4413 O O . PHE B 1 134 ? 29.203 -19.917 -15.519 1.00 15.31 ? 134 PHE B O 1 ATOM 4414 C CB . PHE B 1 134 ? 30.904 -19.830 -18.158 1.00 17.23 ? 134 PHE B CB 1 ATOM 4415 C CG . PHE B 1 134 ? 31.880 -20.953 -17.990 1.00 18.48 ? 134 PHE B CG 1 ATOM 4416 C CD1 . PHE B 1 134 ? 32.068 -21.888 -19.010 1.00 17.78 ? 134 PHE B CD1 1 ATOM 4417 C CD2 . PHE B 1 134 ? 32.605 -21.099 -16.799 1.00 18.94 ? 134 PHE B CD2 1 ATOM 4418 C CE1 . PHE B 1 134 ? 33.008 -22.949 -18.863 1.00 19.15 ? 134 PHE B CE1 1 ATOM 4419 C CE2 . PHE B 1 134 ? 33.509 -22.144 -16.627 1.00 18.99 ? 134 PHE B CE2 1 ATOM 4420 C CZ . PHE B 1 134 ? 33.714 -23.075 -17.669 1.00 19.76 ? 134 PHE B CZ 1 ATOM 4421 N N . ILE B 1 135 ? 29.159 -22.042 -16.285 1.00 16.13 ? 135 ILE B N 1 ATOM 4422 C CA . ILE B 1 135 ? 28.572 -22.584 -15.038 1.00 16.99 ? 135 ILE B CA 1 ATOM 4423 C C . ILE B 1 135 ? 29.448 -23.640 -14.351 1.00 17.42 ? 135 ILE B C 1 ATOM 4424 O O . ILE B 1 135 ? 29.795 -24.654 -14.955 1.00 17.16 ? 135 ILE B O 1 ATOM 4425 C CB . ILE B 1 135 ? 27.163 -23.168 -15.283 1.00 16.97 ? 135 ILE B CB 1 ATOM 4426 C CG1 . ILE B 1 135 ? 26.195 -22.071 -15.696 1.00 16.49 ? 135 ILE B CG1 1 ATOM 4427 C CG2 . ILE B 1 135 ? 26.652 -23.974 -14.066 1.00 15.92 ? 135 ILE B CG2 1 ATOM 4428 C CD1 . ILE B 1 135 ? 24.710 -22.535 -15.723 1.00 18.17 ? 135 ILE B CD1 1 ATOM 4429 N N . ARG B 1 136 ? 29.788 -23.395 -13.085 1.00 17.66 ? 136 ARG B N 1 ATOM 4430 C CA . ARG B 1 136 ? 30.590 -24.348 -12.325 1.00 17.49 ? 136 ARG B CA 1 ATOM 4431 C C . ARG B 1 136 ? 29.892 -24.876 -11.089 1.00 17.54 ? 136 ARG B C 1 ATOM 4432 O O . ARG B 1 136 ? 28.976 -24.245 -10.590 1.00 17.01 ? 136 ARG B O 1 ATOM 4433 C CB . ARG B 1 136 ? 31.917 -23.755 -11.954 1.00 17.64 ? 136 ARG B CB 1 ATOM 4434 C CG . ARG B 1 136 ? 32.773 -23.454 -13.090 1.00 16.51 ? 136 ARG B CG 1 ATOM 4435 C CD . ARG B 1 136 ? 34.049 -22.933 -12.530 1.00 17.69 ? 136 ARG B CD 1 ATOM 4436 N NE . ARG B 1 136 ? 33.800 -21.859 -11.536 1.00 16.36 ? 136 ARG B NE 1 ATOM 4437 C CZ . ARG B 1 136 ? 34.778 -21.249 -10.848 1.00 16.50 ? 136 ARG B CZ 1 ATOM 4438 N NH1 . ARG B 1 136 ? 36.067 -21.581 -11.040 1.00 14.52 ? 136 ARG B NH1 1 ATOM 4439 N NH2 . ARG B 1 136 ? 34.467 -20.277 -9.990 1.00 17.40 ? 136 ARG B NH2 1 ATOM 4440 N N . SER B 1 137 ? 30.307 -26.058 -10.620 1.00 18.23 ? 137 SER B N 1 ATOM 4441 C CA . SER B 1 137 ? 29.678 -26.646 -9.444 1.00 19.90 ? 137 SER B CA 1 ATOM 4442 C C . SER B 1 137 ? 30.655 -27.453 -8.657 1.00 20.22 ? 137 SER B C 1 ATOM 4443 O O . SER B 1 137 ? 31.375 -28.249 -9.222 1.00 21.94 ? 137 SER B O 1 ATOM 4444 C CB . SER B 1 137 ? 28.482 -27.538 -9.840 1.00 20.58 ? 137 SER B CB 1 ATOM 4445 O OG . SER B 1 137 ? 27.890 -28.217 -8.727 1.00 20.88 ? 137 SER B OG 1 ATOM 4446 N N . SER B 1 138 ? 30.673 -27.280 -7.341 1.00 20.85 ? 138 SER B N 1 ATOM 4447 C CA . SER B 1 138 ? 31.484 -28.169 -6.497 1.00 21.06 ? 138 SER B CA 1 ATOM 4448 C C . SER B 1 138 ? 30.933 -29.584 -6.697 1.00 21.51 ? 138 SER B C 1 ATOM 4449 O O . SER B 1 138 ? 29.776 -29.739 -7.109 1.00 21.00 ? 138 SER B O 1 ATOM 4450 C CB . SER B 1 138 ? 31.405 -27.740 -5.029 1.00 20.40 ? 138 SER B CB 1 ATOM 4451 O OG . SER B 1 138 ? 32.335 -28.451 -4.219 1.00 20.39 ? 138 SER B OG 1 ATOM 4452 N N . GLY B 1 139 ? 31.727 -30.603 -6.384 1.00 22.42 ? 139 GLY B N 1 ATOM 4453 C CA . GLY B 1 139 ? 31.302 -31.976 -6.631 1.00 23.71 ? 139 GLY B CA 1 ATOM 4454 C C . GLY B 1 139 ? 30.644 -32.679 -5.461 1.00 25.18 ? 139 GLY B C 1 ATOM 4455 O O . GLY B 1 139 ? 31.337 -33.363 -4.701 1.00 27.37 ? 139 GLY B O 1 ATOM 4456 N N . SER B 1 140 ? 29.323 -32.542 -5.312 1.00 24.52 ? 140 SER B N 1 ATOM 4457 C CA . SER B 1 140 ? 28.566 -33.196 -4.253 1.00 23.57 ? 140 SER B CA 1 ATOM 4458 C C . SER B 1 140 ? 27.178 -33.387 -4.814 1.00 23.39 ? 140 SER B C 1 ATOM 4459 O O . SER B 1 140 ? 26.620 -32.445 -5.370 1.00 23.47 ? 140 SER B O 1 ATOM 4460 C CB . SER B 1 140 ? 28.494 -32.283 -3.032 1.00 23.61 ? 140 SER B CB 1 ATOM 4461 O OG . SER B 1 140 ? 27.461 -32.696 -2.131 1.00 24.04 ? 140 SER B OG 1 ATOM 4462 N N . SER B 1 141 ? 26.595 -34.569 -4.680 1.00 22.53 ? 141 SER B N 1 ATOM 4463 C CA . SER B 1 141 ? 25.308 -34.810 -5.340 1.00 22.90 ? 141 SER B CA 1 ATOM 4464 C C . SER B 1 141 ? 24.333 -33.652 -5.141 1.00 21.79 ? 141 SER B C 1 ATOM 4465 O O . SER B 1 141 ? 23.689 -33.251 -6.095 1.00 22.16 ? 141 SER B O 1 ATOM 4466 C CB . SER B 1 141 ? 24.623 -36.075 -4.856 1.00 22.45 ? 141 SER B CB 1 ATOM 4467 O OG . SER B 1 141 ? 25.577 -37.050 -4.647 1.00 27.96 ? 141 SER B OG 1 ATOM 4468 N N . ARG B 1 142 ? 24.206 -33.140 -3.917 1.00 20.79 ? 142 ARG B N 1 ATOM 4469 C CA . ARG B 1 142 ? 23.194 -32.131 -3.664 1.00 20.41 ? 142 ARG B CA 1 ATOM 4470 C C . ARG B 1 142 ? 23.485 -30.813 -4.374 1.00 19.67 ? 142 ARG B C 1 ATOM 4471 O O . ARG B 1 142 ? 22.565 -30.082 -4.735 1.00 19.66 ? 142 ARG B O 1 ATOM 4472 C CB . ARG B 1 142 ? 22.908 -31.948 -2.181 1.00 20.77 ? 142 ARG B CB 1 ATOM 4473 C CG . ARG B 1 142 ? 24.101 -31.492 -1.306 1.00 22.94 ? 142 ARG B CG 1 ATOM 4474 C CD . ARG B 1 142 ? 23.690 -31.457 0.165 1.00 28.65 ? 142 ARG B CD 1 ATOM 4475 N NE . ARG B 1 142 ? 24.784 -31.111 1.082 1.00 34.97 ? 142 ARG B NE 1 ATOM 4476 C CZ . ARG B 1 142 ? 25.677 -31.988 1.560 1.00 38.54 ? 142 ARG B CZ 1 ATOM 4477 N NH1 . ARG B 1 142 ? 25.620 -33.286 1.216 1.00 38.23 ? 142 ARG B NH1 1 ATOM 4478 N NH2 . ARG B 1 142 ? 26.632 -31.568 2.388 1.00 39.80 ? 142 ARG B NH2 1 ATOM 4479 N N . VAL B 1 143 ? 24.758 -30.542 -4.616 1.00 19.36 ? 143 VAL B N 1 ATOM 4480 C CA . VAL B 1 143 ? 25.176 -29.268 -5.196 1.00 19.56 ? 143 VAL B CA 1 ATOM 4481 C C . VAL B 1 143 ? 24.937 -29.287 -6.711 1.00 18.97 ? 143 VAL B C 1 ATOM 4482 O O . VAL B 1 143 ? 24.249 -28.413 -7.241 1.00 18.21 ? 143 VAL B O 1 ATOM 4483 C CB . VAL B 1 143 ? 26.627 -28.854 -4.780 1.00 19.52 ? 143 VAL B CB 1 ATOM 4484 C CG1 . VAL B 1 143 ? 27.015 -27.491 -5.408 1.00 18.68 ? 143 VAL B CG1 1 ATOM 4485 C CG2 . VAL B 1 143 ? 26.727 -28.773 -3.282 1.00 19.38 ? 143 VAL B CG2 1 ATOM 4486 N N . ILE B 1 144 ? 25.492 -30.322 -7.355 1.00 19.74 ? 144 ILE B N 1 ATOM 4487 C CA . ILE B 1 144 ? 25.265 -30.735 -8.764 1.00 19.29 ? 144 ILE B CA 1 ATOM 4488 C C . ILE B 1 144 ? 23.791 -30.769 -9.129 1.00 18.73 ? 144 ILE B C 1 ATOM 4489 O O . ILE B 1 144 ? 23.350 -30.134 -10.101 1.00 20.01 ? 144 ILE B O 1 ATOM 4490 C CB . ILE B 1 144 ? 25.851 -32.138 -8.987 1.00 19.56 ? 144 ILE B CB 1 ATOM 4491 C CG1 . ILE B 1 144 ? 27.371 -32.115 -8.980 1.00 21.58 ? 144 ILE B CG1 1 ATOM 4492 C CG2 . ILE B 1 144 ? 25.459 -32.683 -10.309 1.00 21.05 ? 144 ILE B CG2 1 ATOM 4493 C CD1 . ILE B 1 144 ? 27.988 -33.563 -8.962 1.00 24.48 ? 144 ILE B CD1 1 ATOM 4494 N N . ALA B 1 145 ? 23.003 -31.488 -8.355 1.00 17.74 ? 145 ALA B N 1 ATOM 4495 C CA . ALA B 1 145 ? 21.558 -31.524 -8.610 1.00 17.00 ? 145 ALA B CA 1 ATOM 4496 C C . ALA B 1 145 ? 20.937 -30.146 -8.528 1.00 16.30 ? 145 ALA B C 1 ATOM 4497 O O . ALA B 1 145 ? 20.038 -29.817 -9.312 1.00 17.05 ? 145 ALA B O 1 ATOM 4498 C CB . ALA B 1 145 ? 20.848 -32.468 -7.635 1.00 16.72 ? 145 ALA B CB 1 ATOM 4499 N N . SER B 1 146 ? 21.416 -29.334 -7.594 1.00 15.83 ? 146 SER B N 1 ATOM 4500 C CA . SER B 1 146 ? 20.850 -27.999 -7.370 1.00 15.17 ? 146 SER B CA 1 ATOM 4501 C C . SER B 1 146 ? 21.233 -27.098 -8.523 1.00 15.10 ? 146 SER B C 1 ATOM 4502 O O . SER B 1 146 ? 20.406 -26.347 -8.989 1.00 15.38 ? 146 SER B O 1 ATOM 4503 C CB . SER B 1 146 ? 21.364 -27.399 -6.071 1.00 15.57 ? 146 SER B CB 1 ATOM 4504 O OG . SER B 1 146 ? 20.738 -27.921 -4.917 1.00 16.50 ? 146 SER B OG 1 ATOM 4505 N N . GLY B 1 147 ? 22.490 -27.158 -8.962 1.00 13.99 ? 147 GLY B N 1 ATOM 4506 C CA . GLY B 1 147 ? 22.882 -26.464 -10.161 1.00 15.40 ? 147 GLY B CA 1 ATOM 4507 C C . GLY B 1 147 ? 21.908 -26.776 -11.308 1.00 16.25 ? 147 GLY B C 1 ATOM 4508 O O . GLY B 1 147 ? 21.376 -25.857 -11.971 1.00 16.00 ? 147 GLY B O 1 ATOM 4509 N N . LYS B 1 148 ? 21.644 -28.064 -11.515 1.00 16.87 ? 148 LYS B N 1 ATOM 4510 C CA . LYS B 1 148 ? 20.776 -28.498 -12.620 1.00 16.93 ? 148 LYS B CA 1 ATOM 4511 C C . LYS B 1 148 ? 19.315 -28.111 -12.449 1.00 17.43 ? 148 LYS B C 1 ATOM 4512 O O . LYS B 1 148 ? 18.625 -27.894 -13.457 1.00 18.62 ? 148 LYS B O 1 ATOM 4513 C CB . LYS B 1 148 ? 20.907 -29.995 -12.842 1.00 17.58 ? 148 LYS B CB 1 ATOM 4514 C CG . LYS B 1 148 ? 22.264 -30.423 -13.422 1.00 17.64 ? 148 LYS B CG 1 ATOM 4515 C CD . LYS B 1 148 ? 22.324 -31.955 -13.536 1.00 19.87 ? 148 LYS B CD 1 ATOM 4516 C CE . LYS B 1 148 ? 23.732 -32.419 -13.912 1.00 22.04 ? 148 LYS B CE 1 ATOM 4517 N NZ . LYS B 1 148 ? 24.095 -33.666 -13.136 1.00 20.71 ? 148 LYS B NZ 1 ATOM 4518 N N . LYS B 1 149 ? 18.833 -27.966 -11.213 1.00 17.55 ? 149 LYS B N 1 ATOM 4519 C CA . LYS B 1 149 ? 17.499 -27.438 -10.998 1.00 17.62 ? 149 LYS B CA 1 ATOM 4520 C C . LYS B 1 149 ? 17.406 -25.930 -11.277 1.00 19.19 ? 149 LYS B C 1 ATOM 4521 O O . LYS B 1 149 ? 16.318 -25.391 -11.619 1.00 21.02 ? 149 LYS B O 1 ATOM 4522 C CB . LYS B 1 149 ? 17.046 -27.702 -9.572 1.00 18.21 ? 149 LYS B CB 1 ATOM 4523 C CG . LYS B 1 149 ? 16.610 -29.128 -9.308 1.00 17.74 ? 149 LYS B CG 1 ATOM 4524 C CD . LYS B 1 149 ? 15.169 -29.347 -9.752 1.00 19.36 ? 149 LYS B CD 1 ATOM 4525 C CE . LYS B 1 149 ? 14.876 -30.870 -10.003 1.00 20.15 ? 149 LYS B CE 1 ATOM 4526 N NZ . LYS B 1 149 ? 13.531 -31.089 -10.616 1.00 19.96 ? 149 LYS B NZ 1 ATOM 4527 N N . PHE B 1 150 ? 18.508 -25.225 -11.065 1.00 18.65 ? 150 PHE B N 1 ATOM 4528 C CA . PHE B 1 150 ? 18.582 -23.837 -11.374 1.00 18.68 ? 150 PHE B CA 1 ATOM 4529 C C . PHE B 1 150 ? 18.633 -23.718 -12.912 1.00 18.92 ? 150 PHE B C 1 ATOM 4530 O O . PHE B 1 150 ? 17.883 -22.951 -13.485 1.00 18.98 ? 150 PHE B O 1 ATOM 4531 C CB . PHE B 1 150 ? 19.821 -23.239 -10.685 1.00 19.16 ? 150 PHE B CB 1 ATOM 4532 C CG . PHE B 1 150 ? 20.176 -21.811 -11.107 1.00 18.33 ? 150 PHE B CG 1 ATOM 4533 C CD1 . PHE B 1 150 ? 20.637 -21.528 -12.392 1.00 18.95 ? 150 PHE B CD1 1 ATOM 4534 C CD2 . PHE B 1 150 ? 20.129 -20.766 -10.178 1.00 18.69 ? 150 PHE B CD2 1 ATOM 4535 C CE1 . PHE B 1 150 ? 20.996 -20.203 -12.740 1.00 18.58 ? 150 PHE B CE1 1 ATOM 4536 C CE2 . PHE B 1 150 ? 20.471 -19.467 -10.506 1.00 16.28 ? 150 PHE B CE2 1 ATOM 4537 C CZ . PHE B 1 150 ? 20.914 -19.188 -11.777 1.00 16.85 ? 150 PHE B CZ 1 ATOM 4538 N N . ILE B 1 151 ? 19.490 -24.485 -13.578 1.00 18.85 ? 151 ILE B N 1 ATOM 4539 C CA . ILE B 1 151 ? 19.516 -24.469 -15.058 1.00 19.73 ? 151 ILE B CA 1 ATOM 4540 C C . ILE B 1 151 ? 18.167 -24.790 -15.675 1.00 20.57 ? 151 ILE B C 1 ATOM 4541 O O . ILE B 1 151 ? 17.790 -24.231 -16.682 1.00 21.44 ? 151 ILE B O 1 ATOM 4542 C CB . ILE B 1 151 ? 20.547 -25.455 -15.631 1.00 19.29 ? 151 ILE B CB 1 ATOM 4543 C CG1 . ILE B 1 151 ? 21.958 -24.931 -15.349 1.00 15.14 ? 151 ILE B CG1 1 ATOM 4544 C CG2 . ILE B 1 151 ? 20.234 -25.759 -17.110 1.00 17.60 ? 151 ILE B CG2 1 ATOM 4545 C CD1 . ILE B 1 151 ? 23.031 -25.980 -15.596 1.00 15.31 ? 151 ILE B CD1 1 ATOM 4546 N N . GLU B 1 152 ? 17.460 -25.712 -15.046 1.00 21.78 ? 152 GLU B N 1 ATOM 4547 C CA . GLU B 1 152 ? 16.106 -26.104 -15.428 1.00 21.96 ? 152 GLU B CA 1 ATOM 4548 C C . GLU B 1 152 ? 15.132 -24.946 -15.462 1.00 21.48 ? 152 GLU B C 1 ATOM 4549 O O . GLU B 1 152 ? 14.457 -24.759 -16.439 1.00 21.23 ? 152 GLU B O 1 ATOM 4550 C CB . GLU B 1 152 ? 15.602 -27.169 -14.446 1.00 22.36 ? 152 GLU B CB 1 ATOM 4551 C CG . GLU B 1 152 ? 14.543 -28.142 -15.012 1.00 23.46 ? 152 GLU B CG 1 ATOM 4552 C CD . GLU B 1 152 ? 14.043 -29.163 -13.993 1.00 23.35 ? 152 GLU B CD 1 ATOM 4553 O OE1 . GLU B 1 152 ? 14.857 -29.770 -13.263 1.00 23.00 ? 152 GLU B OE1 1 ATOM 4554 O OE2 . GLU B 1 152 ? 12.813 -29.371 -13.945 1.00 25.50 ? 152 GLU B OE2 1 ATOM 4555 N N . GLY B 1 153 ? 15.057 -24.188 -14.380 1.00 21.92 ? 153 GLY B N 1 ATOM 4556 C CA . GLY B 1 153 ? 14.143 -23.048 -14.272 1.00 21.57 ? 153 GLY B CA 1 ATOM 4557 C C . GLY B 1 153 ? 14.547 -21.878 -15.152 1.00 21.88 ? 153 GLY B C 1 ATOM 4558 O O . GLY B 1 153 ? 13.687 -21.243 -15.778 1.00 22.15 ? 153 GLY B O 1 ATOM 4559 N N . PHE B 1 154 ? 15.857 -21.609 -15.223 1.00 21.88 ? 154 PHE B N 1 ATOM 4560 C CA . PHE B 1 154 ? 16.431 -20.665 -16.196 1.00 21.97 ? 154 PHE B CA 1 ATOM 4561 C C . PHE B 1 154 ? 15.954 -20.989 -17.618 1.00 22.53 ? 154 PHE B C 1 ATOM 4562 O O . PHE B 1 154 ? 15.462 -20.113 -18.346 1.00 22.54 ? 154 PHE B O 1 ATOM 4563 C CB . PHE B 1 154 ? 17.961 -20.743 -16.124 1.00 21.41 ? 154 PHE B CB 1 ATOM 4564 C CG . PHE B 1 154 ? 18.708 -19.747 -16.996 1.00 19.71 ? 154 PHE B CG 1 ATOM 4565 C CD1 . PHE B 1 154 ? 18.927 -20.002 -18.357 1.00 16.29 ? 154 PHE B CD1 1 ATOM 4566 C CD2 . PHE B 1 154 ? 19.280 -18.587 -16.430 1.00 18.13 ? 154 PHE B CD2 1 ATOM 4567 C CE1 . PHE B 1 154 ? 19.662 -19.101 -19.138 1.00 13.17 ? 154 PHE B CE1 1 ATOM 4568 C CE2 . PHE B 1 154 ? 20.040 -17.694 -17.220 1.00 14.80 ? 154 PHE B CE2 1 ATOM 4569 C CZ . PHE B 1 154 ? 20.208 -17.949 -18.564 1.00 14.42 ? 154 PHE B CZ 1 ATOM 4570 N N . GLN B 1 155 ? 16.095 -22.243 -18.005 1.00 23.12 ? 155 GLN B N 1 ATOM 4571 C CA . GLN B 1 155 ? 15.795 -22.648 -19.370 1.00 24.81 ? 155 GLN B CA 1 ATOM 4572 C C . GLN B 1 155 ? 14.293 -22.561 -19.659 1.00 23.93 ? 155 GLN B C 1 ATOM 4573 O O . GLN B 1 155 ? 13.905 -22.163 -20.761 1.00 24.51 ? 155 GLN B O 1 ATOM 4574 C CB . GLN B 1 155 ? 16.411 -24.029 -19.655 1.00 25.78 ? 155 GLN B CB 1 ATOM 4575 C CG . GLN B 1 155 ? 16.304 -24.559 -21.112 1.00 32.92 ? 155 GLN B CG 1 ATOM 4576 C CD . GLN B 1 155 ? 16.917 -23.619 -22.178 1.00 39.21 ? 155 GLN B CD 1 ATOM 4577 O OE1 . GLN B 1 155 ? 18.142 -23.412 -22.193 1.00 44.02 ? 155 GLN B OE1 1 ATOM 4578 N NE2 . GLN B 1 155 ? 16.063 -23.051 -23.069 1.00 35.84 ? 155 GLN B NE2 1 ATOM 4579 N N . SER B 1 156 ? 13.453 -22.874 -18.669 1.00 23.06 ? 156 SER B N 1 ATOM 4580 C CA . SER B 1 156 ? 11.981 -22.777 -18.806 1.00 22.63 ? 156 SER B CA 1 ATOM 4581 C C . SER B 1 156 ? 11.495 -21.368 -19.024 1.00 21.83 ? 156 SER B C 1 ATOM 4582 O O . SER B 1 156 ? 10.472 -21.162 -19.674 1.00 22.38 ? 156 SER B O 1 ATOM 4583 C CB . SER B 1 156 ? 11.254 -23.306 -17.568 1.00 22.46 ? 156 SER B CB 1 ATOM 4584 O OG . SER B 1 156 ? 11.337 -24.709 -17.525 1.00 24.60 ? 156 SER B OG 1 ATOM 4585 N N . THR B 1 157 ? 12.186 -20.416 -18.414 1.00 20.74 ? 157 THR B N 1 ATOM 4586 C CA . THR B 1 157 ? 11.855 -19.010 -18.524 1.00 20.10 ? 157 THR B CA 1 ATOM 4587 C C . THR B 1 157 ? 12.381 -18.489 -19.858 1.00 20.15 ? 157 THR B C 1 ATOM 4588 O O . THR B 1 157 ? 11.690 -17.765 -20.536 1.00 20.84 ? 157 THR B O 1 ATOM 4589 C CB . THR B 1 157 ? 12.481 -18.245 -17.369 1.00 19.69 ? 157 THR B CB 1 ATOM 4590 O OG1 . THR B 1 157 ? 12.221 -18.963 -16.166 1.00 19.77 ? 157 THR B OG1 1 ATOM 4591 C CG2 . THR B 1 157 ? 11.934 -16.866 -17.258 1.00 17.76 ? 157 THR B CG2 1 ATOM 4592 N N . LYS B 1 158 ? 13.584 -18.894 -20.252 1.00 20.54 ? 158 LYS B N 1 ATOM 4593 C CA . LYS B 1 158 ? 14.149 -18.523 -21.564 1.00 20.95 ? 158 LYS B CA 1 ATOM 4594 C C . LYS B 1 158 ? 13.235 -18.901 -22.741 1.00 22.88 ? 158 LYS B C 1 ATOM 4595 O O . LYS B 1 158 ? 13.047 -18.106 -23.655 1.00 24.27 ? 158 LYS B O 1 ATOM 4596 C CB . LYS B 1 158 ? 15.579 -19.098 -21.763 1.00 19.75 ? 158 LYS B CB 1 ATOM 4597 C CG . LYS B 1 158 ? 16.332 -18.429 -22.928 1.00 17.12 ? 158 LYS B CG 1 ATOM 4598 C CD . LYS B 1 158 ? 17.678 -19.003 -23.198 1.00 12.66 ? 158 LYS B CD 1 ATOM 4599 C CE . LYS B 1 158 ? 18.503 -18.108 -24.168 1.00 11.96 ? 158 LYS B CE 1 ATOM 4600 N NZ . LYS B 1 158 ? 19.712 -18.893 -24.631 1.00 15.07 ? 158 LYS B NZ 1 ATOM 4601 N N . LEU B 1 159 ? 12.672 -20.108 -22.728 1.00 24.53 ? 159 LEU B N 1 ATOM 4602 C CA . LEU B 1 159 ? 11.705 -20.505 -23.738 1.00 25.53 ? 159 LEU B CA 1 ATOM 4603 C C . LEU B 1 159 ? 10.422 -19.675 -23.726 1.00 26.04 ? 159 LEU B C 1 ATOM 4604 O O . LEU B 1 159 ? 9.781 -19.527 -24.764 1.00 26.59 ? 159 LEU B O 1 ATOM 4605 C CB . LEU B 1 159 ? 11.317 -21.982 -23.589 1.00 26.39 ? 159 LEU B CB 1 ATOM 4606 C CG . LEU B 1 159 ? 12.218 -23.123 -24.095 1.00 28.66 ? 159 LEU B CG 1 ATOM 4607 C CD1 . LEU B 1 159 ? 11.629 -24.502 -23.681 1.00 30.09 ? 159 LEU B CD1 1 ATOM 4608 C CD2 . LEU B 1 159 ? 12.508 -23.070 -25.612 1.00 27.46 ? 159 LEU B CD2 1 ATOM 4609 N N . LYS B 1 160 ? 9.982 -19.177 -22.586 1.00 26.18 ? 160 LYS B N 1 ATOM 4610 C CA . LYS B 1 160 ? 8.740 -18.380 -22.652 1.00 27.15 ? 160 LYS B CA 1 ATOM 4611 C C . LYS B 1 160 ? 8.989 -16.911 -22.956 1.00 27.08 ? 160 LYS B C 1 ATOM 4612 O O . LYS B 1 160 ? 8.070 -16.081 -22.899 1.00 26.39 ? 160 LYS B O 1 ATOM 4613 C CB . LYS B 1 160 ? 7.873 -18.547 -21.410 1.00 27.69 ? 160 LYS B CB 1 ATOM 4614 C CG . LYS B 1 160 ? 7.227 -19.934 -21.335 1.00 30.52 ? 160 LYS B CG 1 ATOM 4615 C CD . LYS B 1 160 ? 6.110 -20.046 -20.267 1.00 37.26 ? 160 LYS B CD 1 ATOM 4616 C CE . LYS B 1 160 ? 6.662 -20.294 -18.835 1.00 39.39 ? 160 LYS B CE 1 ATOM 4617 N NZ . LYS B 1 160 ? 7.128 -19.035 -18.162 1.00 38.44 ? 160 LYS B NZ 1 ATOM 4618 N N . ASP B 1 161 ? 10.236 -16.592 -23.309 1.00 26.68 ? 161 ASP B N 1 ATOM 4619 C CA . ASP B 1 161 ? 10.616 -15.212 -23.416 1.00 26.55 ? 161 ASP B CA 1 ATOM 4620 C C . ASP B 1 161 ? 10.653 -14.779 -24.883 1.00 26.99 ? 161 ASP B C 1 ATOM 4621 O O . ASP B 1 161 ? 11.494 -15.238 -25.639 1.00 27.07 ? 161 ASP B O 1 ATOM 4622 C CB . ASP B 1 161 ? 11.948 -14.996 -22.709 1.00 26.20 ? 161 ASP B CB 1 ATOM 4623 C CG . ASP B 1 161 ? 12.490 -13.586 -22.884 1.00 24.35 ? 161 ASP B CG 1 ATOM 4624 O OD1 . ASP B 1 161 ? 11.718 -12.689 -23.267 1.00 26.00 ? 161 ASP B OD1 1 ATOM 4625 O OD2 . ASP B 1 161 ? 13.703 -13.383 -22.639 1.00 19.97 ? 161 ASP B OD2 1 ATOM 4626 N N . PRO B 1 162 ? 9.749 -13.870 -25.276 1.00 27.05 ? 162 PRO B N 1 ATOM 4627 C CA . PRO B 1 162 ? 9.656 -13.456 -26.670 1.00 26.93 ? 162 PRO B CA 1 ATOM 4628 C C . PRO B 1 162 ? 10.951 -12.798 -27.212 1.00 27.61 ? 162 PRO B C 1 ATOM 4629 O O . PRO B 1 162 ? 11.237 -12.881 -28.406 1.00 25.70 ? 162 PRO B O 1 ATOM 4630 C CB . PRO B 1 162 ? 8.487 -12.460 -26.659 1.00 27.51 ? 162 PRO B CB 1 ATOM 4631 C CG . PRO B 1 162 ? 8.404 -11.939 -25.241 1.00 26.49 ? 162 PRO B CG 1 ATOM 4632 C CD . PRO B 1 162 ? 8.885 -13.066 -24.377 1.00 27.28 ? 162 PRO B CD 1 ATOM 4633 N N . ARG B 1 163 ? 11.744 -12.172 -26.338 1.00 28.79 ? 163 ARG B N 1 ATOM 4634 C CA . ARG B 1 163 ? 12.975 -11.518 -26.791 1.00 29.23 ? 163 ARG B CA 1 ATOM 4635 C C . ARG B 1 163 ? 14.208 -12.412 -26.830 1.00 28.86 ? 163 ARG B C 1 ATOM 4636 O O . ARG B 1 163 ? 15.282 -11.926 -27.157 1.00 28.53 ? 163 ARG B O 1 ATOM 4637 C CB . ARG B 1 163 ? 13.243 -10.256 -25.992 1.00 29.82 ? 163 ARG B CB 1 ATOM 4638 C CG . ARG B 1 163 ? 12.053 -9.362 -25.966 1.00 32.35 ? 163 ARG B CG 1 ATOM 4639 C CD . ARG B 1 163 ? 12.091 -8.360 -24.857 1.00 35.77 ? 163 ARG B CD 1 ATOM 4640 N NE . ARG B 1 163 ? 10.788 -8.321 -24.201 1.00 41.07 ? 163 ARG B NE 1 ATOM 4641 C CZ . ARG B 1 163 ? 9.698 -7.745 -24.696 1.00 41.37 ? 163 ARG B CZ 1 ATOM 4642 N NH1 . ARG B 1 163 ? 9.739 -7.159 -25.873 1.00 42.28 ? 163 ARG B NH1 1 ATOM 4643 N NH2 . ARG B 1 163 ? 8.559 -7.776 -24.018 1.00 41.52 ? 163 ARG B NH2 1 ATOM 4644 N N . ALA B 1 164 ? 14.045 -13.706 -26.555 1.00 28.56 ? 164 ALA B N 1 ATOM 4645 C CA . ALA B 1 164 ? 15.164 -14.652 -26.532 1.00 29.39 ? 164 ALA B CA 1 ATOM 4646 C C . ALA B 1 164 ? 15.709 -14.965 -27.921 1.00 30.09 ? 164 ALA B C 1 ATOM 4647 O O . ALA B 1 164 ? 14.914 -15.049 -28.859 1.00 31.38 ? 164 ALA B O 1 ATOM 4648 C CB . ALA B 1 164 ? 14.738 -15.946 -25.847 1.00 28.81 ? 164 ALA B CB 1 ATOM 4649 N N . GLN B 1 165 ? 17.035 -15.154 -28.053 1.00 29.93 ? 165 GLN B N 1 ATOM 4650 C CA . GLN B 1 165 ? 17.626 -15.777 -29.234 1.00 30.24 ? 165 GLN B CA 1 ATOM 4651 C C . GLN B 1 165 ? 17.591 -17.313 -29.044 1.00 31.79 ? 165 GLN B C 1 ATOM 4652 O O . GLN B 1 165 ? 18.406 -17.872 -28.290 1.00 31.97 ? 165 GLN B O 1 ATOM 4653 C CB . GLN B 1 165 ? 19.053 -15.260 -29.504 1.00 29.88 ? 165 GLN B CB 1 ATOM 4654 C CG . GLN B 1 165 ? 19.757 -15.945 -30.677 1.00 28.64 ? 165 GLN B CG 1 ATOM 4655 C CD . GLN B 1 165 ? 21.120 -15.317 -31.044 1.00 30.05 ? 165 GLN B CD 1 ATOM 4656 O OE1 . GLN B 1 165 ? 21.420 -14.160 -30.712 1.00 31.57 ? 165 GLN B OE1 1 ATOM 4657 N NE2 . GLN B 1 165 ? 21.938 -16.079 -31.760 1.00 29.00 ? 165 GLN B NE2 1 ATOM 4658 N N . PRO B 1 166 ? 16.638 -18.010 -29.714 1.00 32.83 ? 166 PRO B N 1 ATOM 4659 C CA . PRO B 1 166 ? 16.386 -19.440 -29.500 1.00 33.03 ? 166 PRO B CA 1 ATOM 4660 C C . PRO B 1 166 ? 17.356 -20.310 -30.284 1.00 33.30 ? 166 PRO B C 1 ATOM 4661 O O . PRO B 1 166 ? 18.058 -19.789 -31.147 1.00 33.05 ? 166 PRO B O 1 ATOM 4662 C CB . PRO B 1 166 ? 14.966 -19.622 -30.020 1.00 33.43 ? 166 PRO B CB 1 ATOM 4663 C CG . PRO B 1 166 ? 14.867 -18.645 -31.160 1.00 33.55 ? 166 PRO B CG 1 ATOM 4664 C CD . PRO B 1 166 ? 15.780 -17.468 -30.785 1.00 33.41 ? 166 PRO B CD 1 ATOM 4665 N N . GLY B 1 167 ? 17.425 -21.604 -29.946 1.00 33.53 ? 167 GLY B N 1 ATOM 4666 C CA . GLY B 1 167 ? 18.380 -22.522 -30.574 1.00 33.91 ? 167 GLY B CA 1 ATOM 4667 C C . GLY B 1 167 ? 19.872 -22.225 -30.350 1.00 34.13 ? 167 GLY B C 1 ATOM 4668 O O . GLY B 1 167 ? 20.728 -22.508 -31.226 1.00 34.39 ? 167 GLY B O 1 ATOM 4669 N N . GLN B 1 168 ? 20.188 -21.641 -29.185 1.00 33.48 ? 168 GLN B N 1 ATOM 4670 C CA . GLN B 1 168 ? 21.572 -21.561 -28.697 1.00 32.19 ? 168 GLN B CA 1 ATOM 4671 C C . GLN B 1 168 ? 21.802 -22.836 -27.921 1.00 31.25 ? 168 GLN B C 1 ATOM 4672 O O . GLN B 1 168 ? 20.835 -23.558 -27.597 1.00 31.40 ? 168 GLN B O 1 ATOM 4673 C CB . GLN B 1 168 ? 21.783 -20.357 -27.798 1.00 32.28 ? 168 GLN B CB 1 ATOM 4674 C CG . GLN B 1 168 ? 21.763 -19.019 -28.532 1.00 33.12 ? 168 GLN B CG 1 ATOM 4675 C CD . GLN B 1 168 ? 21.988 -17.855 -27.595 1.00 33.52 ? 168 GLN B CD 1 ATOM 4676 O OE1 . GLN B 1 168 ? 21.270 -17.688 -26.606 1.00 31.38 ? 168 GLN B OE1 1 ATOM 4677 N NE2 . GLN B 1 168 ? 22.978 -17.037 -27.900 1.00 33.04 ? 168 GLN B NE2 1 ATOM 4678 N N . SER B 1 169 ? 23.059 -23.157 -27.625 1.00 30.07 ? 169 SER B N 1 ATOM 4679 C CA . SER B 1 169 ? 23.280 -24.366 -26.812 1.00 28.94 ? 169 SER B CA 1 ATOM 4680 C C . SER B 1 169 ? 22.621 -24.203 -25.451 1.00 28.04 ? 169 SER B C 1 ATOM 4681 O O . SER B 1 169 ? 22.444 -23.094 -24.946 1.00 27.60 ? 169 SER B O 1 ATOM 4682 C CB . SER B 1 169 ? 24.754 -24.756 -26.713 1.00 28.15 ? 169 SER B CB 1 ATOM 4683 O OG . SER B 1 169 ? 25.503 -23.650 -26.345 1.00 28.56 ? 169 SER B OG 1 ATOM 4684 N N . SER B 1 170 ? 22.170 -25.318 -24.911 1.00 27.98 ? 170 SER B N 1 ATOM 4685 C CA . SER B 1 170 ? 21.822 -25.396 -23.490 1.00 28.26 ? 170 SER B CA 1 ATOM 4686 C C . SER B 1 170 ? 22.860 -24.738 -22.556 1.00 26.24 ? 170 SER B C 1 ATOM 4687 O O . SER B 1 170 ? 24.086 -24.814 -22.777 1.00 24.83 ? 170 SER B O 1 ATOM 4688 C CB . SER B 1 170 ? 21.659 -26.874 -23.079 1.00 28.94 ? 170 SER B CB 1 ATOM 4689 O OG . SER B 1 170 ? 20.308 -27.288 -23.232 1.00 33.66 ? 170 SER B OG 1 ATOM 4690 N N . PRO B 1 171 ? 22.372 -24.093 -21.499 1.00 25.46 ? 171 PRO B N 1 ATOM 4691 C CA . PRO B 1 171 ? 23.299 -23.945 -20.383 1.00 25.19 ? 171 PRO B CA 1 ATOM 4692 C C . PRO B 1 171 ? 23.483 -25.327 -19.715 1.00 25.11 ? 171 PRO B C 1 ATOM 4693 O O . PRO B 1 171 ? 22.540 -26.139 -19.677 1.00 25.29 ? 171 PRO B O 1 ATOM 4694 C CB . PRO B 1 171 ? 22.580 -22.964 -19.474 1.00 25.44 ? 171 PRO B CB 1 ATOM 4695 C CG . PRO B 1 171 ? 21.137 -23.069 -19.835 1.00 25.02 ? 171 PRO B CG 1 ATOM 4696 C CD . PRO B 1 171 ? 21.040 -23.540 -21.228 1.00 24.87 ? 171 PRO B CD 1 ATOM 4697 N N . LYS B 1 172 ? 24.683 -25.628 -19.225 1.00 25.13 ? 172 LYS B N 1 ATOM 4698 C CA . LYS B 1 172 ? 24.928 -26.909 -18.552 1.00 24.66 ? 172 LYS B CA 1 ATOM 4699 C C . LYS B 1 172 ? 25.932 -26.675 -17.443 1.00 24.72 ? 172 LYS B C 1 ATOM 4700 O O . LYS B 1 172 ? 26.422 -25.545 -17.307 1.00 25.35 ? 172 LYS B O 1 ATOM 4701 C CB . LYS B 1 172 ? 25.502 -27.888 -19.544 1.00 24.67 ? 172 LYS B CB 1 ATOM 4702 C CG . LYS B 1 172 ? 26.759 -27.319 -20.186 1.00 26.12 ? 172 LYS B CG 1 ATOM 4703 C CD . LYS B 1 172 ? 27.404 -28.222 -21.167 1.00 24.62 ? 172 LYS B CD 1 ATOM 4704 C CE . LYS B 1 172 ? 28.122 -27.380 -22.163 1.00 25.57 ? 172 LYS B CE 1 ATOM 4705 N NZ . LYS B 1 172 ? 29.011 -28.303 -22.859 1.00 29.73 ? 172 LYS B NZ 1 ATOM 4706 N N . ILE B 1 173 ? 26.257 -27.720 -16.661 1.00 23.84 ? 173 ILE B N 1 ATOM 4707 C CA . ILE B 1 173 ? 27.352 -27.612 -15.715 1.00 22.53 ? 173 ILE B CA 1 ATOM 4708 C C . ILE B 1 173 ? 28.687 -27.854 -16.405 1.00 23.35 ? 173 ILE B C 1 ATOM 4709 O O . ILE B 1 173 ? 29.069 -28.981 -16.680 1.00 24.08 ? 173 ILE B O 1 ATOM 4710 C CB . ILE B 1 173 ? 27.188 -28.525 -14.508 1.00 22.03 ? 173 ILE B CB 1 ATOM 4711 C CG1 . ILE B 1 173 ? 25.903 -28.181 -13.793 1.00 18.68 ? 173 ILE B CG1 1 ATOM 4712 C CG2 . ILE B 1 173 ? 28.366 -28.333 -13.557 1.00 21.03 ? 173 ILE B CG2 1 ATOM 4713 C CD1 . ILE B 1 173 ? 25.623 -29.117 -12.683 1.00 19.05 ? 173 ILE B CD1 1 ATOM 4714 N N . ASP B 1 174 ? 29.392 -26.780 -16.692 1.00 23.75 ? 174 ASP B N 1 ATOM 4715 C CA . ASP B 1 174 ? 30.544 -26.872 -17.554 1.00 24.98 ? 174 ASP B CA 1 ATOM 4716 C C . ASP B 1 174 ? 31.703 -27.553 -16.901 1.00 25.62 ? 174 ASP B C 1 ATOM 4717 O O . ASP B 1 174 ? 32.575 -28.081 -17.576 1.00 26.88 ? 174 ASP B O 1 ATOM 4718 C CB . ASP B 1 174 ? 30.981 -25.488 -18.000 1.00 25.02 ? 174 ASP B CB 1 ATOM 4719 C CG . ASP B 1 174 ? 29.930 -24.789 -18.847 1.00 26.05 ? 174 ASP B CG 1 ATOM 4720 O OD1 . ASP B 1 174 ? 29.896 -25.053 -20.057 1.00 28.60 ? 174 ASP B OD1 1 ATOM 4721 O OD2 . ASP B 1 174 ? 29.167 -23.970 -18.311 1.00 24.39 ? 174 ASP B OD2 1 ATOM 4722 N N . VAL B 1 175 ? 31.747 -27.507 -15.579 1.00 25.93 ? 175 VAL B N 1 ATOM 4723 C CA . VAL B 1 175 ? 32.901 -27.981 -14.856 1.00 25.01 ? 175 VAL B CA 1 ATOM 4724 C C . VAL B 1 175 ? 32.339 -28.414 -13.520 1.00 25.38 ? 175 VAL B C 1 ATOM 4725 O O . VAL B 1 175 ? 31.759 -27.591 -12.792 1.00 25.37 ? 175 VAL B O 1 ATOM 4726 C CB . VAL B 1 175 ? 33.939 -26.857 -14.635 1.00 24.65 ? 175 VAL B CB 1 ATOM 4727 C CG1 . VAL B 1 175 ? 34.982 -27.277 -13.602 1.00 23.44 ? 175 VAL B CG1 1 ATOM 4728 C CG2 . VAL B 1 175 ? 34.610 -26.464 -15.915 1.00 24.50 ? 175 VAL B CG2 1 ATOM 4729 N N . VAL B 1 176 ? 32.477 -29.709 -13.220 1.00 25.83 ? 176 VAL B N 1 ATOM 4730 C CA . VAL B 1 176 ? 32.304 -30.204 -11.855 1.00 25.77 ? 176 VAL B CA 1 ATOM 4731 C C . VAL B 1 176 ? 33.685 -30.176 -11.206 1.00 25.97 ? 176 VAL B C 1 ATOM 4732 O O . VAL B 1 176 ? 34.621 -30.851 -11.703 1.00 26.08 ? 176 VAL B O 1 ATOM 4733 C CB . VAL B 1 176 ? 31.765 -31.642 -11.828 1.00 26.09 ? 176 VAL B CB 1 ATOM 4734 C CG1 . VAL B 1 176 ? 31.589 -32.109 -10.380 1.00 27.14 ? 176 VAL B CG1 1 ATOM 4735 C CG2 . VAL B 1 176 ? 30.454 -31.743 -12.568 1.00 25.11 ? 176 VAL B CG2 1 ATOM 4736 N N . ILE B 1 177 ? 33.819 -29.378 -10.135 1.00 24.93 ? 177 ILE B N 1 ATOM 4737 C CA . ILE B 1 177 ? 35.056 -29.320 -9.363 1.00 23.59 ? 177 ILE B CA 1 ATOM 4738 C C . ILE B 1 177 ? 35.044 -30.340 -8.209 1.00 23.63 ? 177 ILE B C 1 ATOM 4739 O O . ILE B 1 177 ? 34.137 -30.357 -7.365 1.00 23.39 ? 177 ILE B O 1 ATOM 4740 C CB . ILE B 1 177 ? 35.322 -27.944 -8.718 1.00 23.39 ? 177 ILE B CB 1 ATOM 4741 C CG1 . ILE B 1 177 ? 35.250 -26.807 -9.720 1.00 21.51 ? 177 ILE B CG1 1 ATOM 4742 C CG2 . ILE B 1 177 ? 36.663 -27.963 -8.032 1.00 21.83 ? 177 ILE B CG2 1 ATOM 4743 C CD1 . ILE B 1 177 ? 35.615 -25.473 -9.110 1.00 20.94 ? 177 ILE B CD1 1 ATOM 4744 N N . SER B 1 178 ? 36.105 -31.130 -8.144 1.00 23.46 ? 178 SER B N 1 ATOM 4745 C CA . SER B 1 178 ? 36.230 -32.174 -7.143 1.00 23.96 ? 178 SER B CA 1 ATOM 4746 C C . SER B 1 178 ? 36.357 -31.720 -5.673 1.00 24.18 ? 178 SER B C 1 ATOM 4747 O O . SER B 1 178 ? 37.020 -30.739 -5.353 1.00 23.61 ? 178 SER B O 1 ATOM 4748 C CB . SER B 1 178 ? 37.399 -33.101 -7.513 1.00 23.41 ? 178 SER B CB 1 ATOM 4749 O OG . SER B 1 178 ? 37.504 -34.140 -6.559 1.00 24.63 ? 178 SER B OG 1 ATOM 4750 N N . GLU B 1 179 ? 35.722 -32.485 -4.798 1.00 24.62 ? 179 GLU B N 1 ATOM 4751 C CA . GLU B 1 179 ? 35.831 -32.338 -3.360 1.00 25.18 ? 179 GLU B CA 1 ATOM 4752 C C . GLU B 1 179 ? 36.857 -33.293 -2.701 1.00 25.38 ? 179 GLU B C 1 ATOM 4753 O O . GLU B 1 179 ? 37.047 -33.238 -1.483 1.00 24.25 ? 179 GLU B O 1 ATOM 4754 C CB . GLU B 1 179 ? 34.454 -32.542 -2.733 1.00 25.21 ? 179 GLU B CB 1 ATOM 4755 C CG . GLU B 1 179 ? 33.464 -31.511 -3.231 1.00 27.33 ? 179 GLU B CG 1 ATOM 4756 C CD . GLU B 1 179 ? 32.228 -31.335 -2.352 1.00 29.81 ? 179 GLU B CD 1 ATOM 4757 O OE1 . GLU B 1 179 ? 31.880 -32.209 -1.527 1.00 29.94 ? 179 GLU B OE1 1 ATOM 4758 O OE2 . GLU B 1 179 ? 31.593 -30.277 -2.512 1.00 33.17 ? 179 GLU B OE2 1 ATOM 4759 N N . ALA B 1 180 ? 37.510 -34.163 -3.489 1.00 26.12 ? 180 ALA B N 1 ATOM 4760 C CA . ALA B 1 180 ? 38.524 -35.086 -2.905 1.00 26.77 ? 180 ALA B CA 1 ATOM 4761 C C . ALA B 1 180 ? 39.520 -34.250 -2.146 1.00 27.47 ? 180 ALA B C 1 ATOM 4762 O O . ALA B 1 180 ? 39.811 -33.107 -2.529 1.00 27.82 ? 180 ALA B O 1 ATOM 4763 C CB . ALA B 1 180 ? 39.244 -35.918 -3.950 1.00 26.14 ? 180 ALA B CB 1 ATOM 4764 N N . SER B 1 181 ? 40.036 -34.829 -1.072 1.00 28.04 ? 181 SER B N 1 ATOM 4765 C CA . SER B 1 181 ? 40.874 -34.124 -0.104 1.00 28.29 ? 181 SER B CA 1 ATOM 4766 C C . SER B 1 181 ? 42.093 -33.492 -0.755 1.00 27.72 ? 181 SER B C 1 ATOM 4767 O O . SER B 1 181 ? 42.653 -32.566 -0.195 1.00 28.44 ? 181 SER B O 1 ATOM 4768 C CB . SER B 1 181 ? 41.271 -35.066 1.052 1.00 28.66 ? 181 SER B CB 1 ATOM 4769 O OG . SER B 1 181 ? 41.584 -36.382 0.547 1.00 29.40 ? 181 SER B OG 1 ATOM 4770 N N . SER B 1 182 ? 42.489 -33.960 -1.940 1.00 27.01 ? 182 SER B N 1 ATOM 4771 C CA . SER B 1 182 ? 43.639 -33.366 -2.613 1.00 26.68 ? 182 SER B CA 1 ATOM 4772 C C . SER B 1 182 ? 43.270 -32.394 -3.723 1.00 25.86 ? 182 SER B C 1 ATOM 4773 O O . SER B 1 182 ? 44.169 -31.906 -4.434 1.00 25.90 ? 182 SER B O 1 ATOM 4774 C CB . SER B 1 182 ? 44.529 -34.440 -3.214 1.00 27.21 ? 182 SER B CB 1 ATOM 4775 O OG . SER B 1 182 ? 43.941 -34.965 -4.401 1.00 28.72 ? 182 SER B OG 1 ATOM 4776 N N . SER B 1 183 ? 41.968 -32.150 -3.898 1.00 24.06 ? 183 SER B N 1 ATOM 4777 C CA . SER B 1 183 ? 41.484 -31.274 -4.956 1.00 23.27 ? 183 SER B CA 1 ATOM 4778 C C . SER B 1 183 ? 41.555 -29.772 -4.594 1.00 22.47 ? 183 SER B C 1 ATOM 4779 O O . SER B 1 183 ? 40.934 -29.336 -3.604 1.00 23.01 ? 183 SER B O 1 ATOM 4780 C CB . SER B 1 183 ? 40.044 -31.647 -5.317 1.00 23.85 ? 183 SER B CB 1 ATOM 4781 O OG . SER B 1 183 ? 39.547 -30.833 -6.369 1.00 22.15 ? 183 SER B OG 1 ATOM 4782 N N . ASN B 1 184 ? 42.302 -28.992 -5.384 1.00 20.61 ? 184 ASN B N 1 ATOM 4783 C CA . ASN B 1 184 ? 42.266 -27.529 -5.244 1.00 19.26 ? 184 ASN B CA 1 ATOM 4784 C C . ASN B 1 184 ? 40.864 -27.082 -5.659 1.00 18.15 ? 184 ASN B C 1 ATOM 4785 O O . ASN B 1 184 ? 40.571 -26.997 -6.827 1.00 18.24 ? 184 ASN B O 1 ATOM 4786 C CB . ASN B 1 184 ? 43.397 -26.846 -6.048 1.00 18.94 ? 184 ASN B CB 1 ATOM 4787 C CG . ASN B 1 184 ? 44.777 -27.203 -5.521 1.00 19.60 ? 184 ASN B CG 1 ATOM 4788 O OD1 . ASN B 1 184 ? 44.869 -27.827 -4.469 1.00 22.47 ? 184 ASN B OD1 1 ATOM 4789 N ND2 . ASN B 1 184 ? 45.864 -26.813 -6.230 1.00 19.77 ? 184 ASN B ND2 1 ATOM 4790 N N . ASN B 1 185 ? 39.969 -26.867 -4.695 1.00 17.86 ? 185 ASN B N 1 ATOM 4791 C CA . ASN B 1 185 ? 38.572 -26.497 -4.989 1.00 16.76 ? 185 ASN B CA 1 ATOM 4792 C C . ASN B 1 185 ? 38.268 -25.073 -4.481 1.00 17.14 ? 185 ASN B C 1 ATOM 4793 O O . ASN B 1 185 ? 38.229 -24.873 -3.259 1.00 17.36 ? 185 ASN B O 1 ATOM 4794 C CB . ASN B 1 185 ? 37.675 -27.520 -4.324 1.00 16.00 ? 185 ASN B CB 1 ATOM 4795 C CG . ASN B 1 185 ? 36.192 -27.209 -4.463 1.00 17.26 ? 185 ASN B CG 1 ATOM 4796 O OD1 . ASN B 1 185 ? 35.350 -28.088 -4.275 1.00 18.01 ? 185 ASN B OD1 1 ATOM 4797 N ND2 . ASN B 1 185 ? 35.856 -25.975 -4.810 1.00 19.46 ? 185 ASN B ND2 1 ATOM 4798 N N . THR B 1 186 ? 38.015 -24.085 -5.353 1.00 16.60 ? 186 THR B N 1 ATOM 4799 C CA . THR B 1 186 ? 37.843 -22.708 -4.834 1.00 17.34 ? 186 THR B CA 1 ATOM 4800 C C . THR B 1 186 ? 36.449 -22.443 -4.268 1.00 18.19 ? 186 THR B C 1 ATOM 4801 O O . THR B 1 186 ? 36.204 -21.430 -3.588 1.00 17.89 ? 186 THR B O 1 ATOM 4802 C CB . THR B 1 186 ? 38.148 -21.598 -5.860 1.00 16.85 ? 186 THR B CB 1 ATOM 4803 O OG1 . THR B 1 186 ? 37.284 -21.741 -6.977 1.00 19.07 ? 186 THR B OG1 1 ATOM 4804 C CG2 . THR B 1 186 ? 39.550 -21.658 -6.358 1.00 15.76 ? 186 THR B CG2 1 ATOM 4805 N N . LEU B 1 187 ? 35.535 -23.354 -4.551 1.00 19.23 ? 187 LEU B N 1 ATOM 4806 C CA . LEU B 1 187 ? 34.142 -23.191 -4.123 1.00 20.47 ? 187 LEU B CA 1 ATOM 4807 C C . LEU B 1 187 ? 33.981 -23.550 -2.662 1.00 20.55 ? 187 LEU B C 1 ATOM 4808 O O . LEU B 1 187 ? 33.071 -23.053 -2.020 1.00 20.72 ? 187 LEU B O 1 ATOM 4809 C CB . LEU B 1 187 ? 33.188 -24.023 -5.001 1.00 20.26 ? 187 LEU B CB 1 ATOM 4810 C CG . LEU B 1 187 ? 33.203 -23.768 -6.522 1.00 21.06 ? 187 LEU B CG 1 ATOM 4811 C CD1 . LEU B 1 187 ? 32.222 -24.690 -7.238 1.00 18.10 ? 187 LEU B CD1 1 ATOM 4812 C CD2 . LEU B 1 187 ? 32.906 -22.320 -6.862 1.00 18.43 ? 187 LEU B CD2 1 ATOM 4813 N N . ASP B 1 188 ? 34.877 -24.406 -2.150 1.00 21.17 ? 188 ASP B N 1 ATOM 4814 C CA . ASP B 1 188 ? 34.851 -24.864 -0.743 1.00 22.11 ? 188 ASP B CA 1 ATOM 4815 C C . ASP B 1 188 ? 36.158 -25.633 -0.476 1.00 21.50 ? 188 ASP B C 1 ATOM 4816 O O . ASP B 1 188 ? 36.166 -26.874 -0.508 1.00 21.21 ? 188 ASP B O 1 ATOM 4817 C CB . ASP B 1 188 ? 33.630 -25.738 -0.501 1.00 22.95 ? 188 ASP B CB 1 ATOM 4818 C CG . ASP B 1 188 ? 33.514 -26.224 0.937 1.00 27.47 ? 188 ASP B CG 1 ATOM 4819 O OD1 . ASP B 1 188 ? 32.881 -25.553 1.787 1.00 30.14 ? 188 ASP B OD1 1 ATOM 4820 O OD2 . ASP B 1 188 ? 34.019 -27.333 1.202 1.00 35.59 ? 188 ASP B OD2 1 ATOM 4821 N N . PRO B 1 189 ? 37.278 -24.892 -0.269 1.00 20.82 ? 189 PRO B N 1 ATOM 4822 C CA . PRO B 1 189 ? 38.604 -25.499 -0.274 1.00 20.72 ? 189 PRO B CA 1 ATOM 4823 C C . PRO B 1 189 ? 38.793 -26.529 0.821 1.00 20.98 ? 189 PRO B C 1 ATOM 4824 O O . PRO B 1 189 ? 38.180 -26.439 1.872 1.00 19.50 ? 189 PRO B O 1 ATOM 4825 C CB . PRO B 1 189 ? 39.537 -24.317 -0.068 1.00 20.28 ? 189 PRO B CB 1 ATOM 4826 C CG . PRO B 1 189 ? 38.738 -23.162 -0.371 1.00 19.81 ? 189 PRO B CG 1 ATOM 4827 C CD . PRO B 1 189 ? 37.358 -23.437 -0.058 1.00 19.66 ? 189 PRO B CD 1 ATOM 4828 N N . GLY B 1 190 ? 39.621 -27.525 0.546 1.00 21.61 ? 190 GLY B N 1 ATOM 4829 C CA . GLY B 1 190 ? 39.775 -28.613 1.494 1.00 23.31 ? 190 GLY B CA 1 ATOM 4830 C C . GLY B 1 190 ? 41.217 -28.934 1.773 1.00 24.05 ? 190 GLY B C 1 ATOM 4831 O O . GLY B 1 190 ? 41.507 -29.952 2.399 1.00 24.82 ? 190 GLY B O 1 ATOM 4832 N N . THR B 1 191 ? 42.121 -28.082 1.303 1.00 24.47 ? 191 THR B N 1 ATOM 4833 C CA . THR B 1 191 ? 43.539 -28.403 1.370 1.00 25.68 ? 191 THR B CA 1 ATOM 4834 C C . THR B 1 191 ? 44.318 -27.688 2.454 1.00 25.86 ? 191 THR B C 1 ATOM 4835 O O . THR B 1 191 ? 45.447 -28.034 2.694 1.00 26.58 ? 191 THR B O 1 ATOM 4836 C CB . THR B 1 191 ? 44.275 -28.162 0.023 1.00 25.67 ? 191 THR B CB 1 ATOM 4837 O OG1 . THR B 1 191 ? 43.718 -27.009 -0.652 1.00 25.97 ? 191 THR B OG1 1 ATOM 4838 C CG2 . THR B 1 191 ? 44.183 -29.392 -0.846 1.00 26.02 ? 191 THR B CG2 1 ATOM 4839 N N . CYS B 1 192 ? 43.736 -26.688 3.087 1.00 26.39 ? 192 CYS B N 1 ATOM 4840 C CA . CYS B 1 192 ? 44.436 -25.936 4.128 1.00 27.56 ? 192 CYS B CA 1 ATOM 4841 C C . CYS B 1 192 ? 44.472 -26.755 5.434 1.00 28.02 ? 192 CYS B C 1 ATOM 4842 O O . CYS B 1 192 ? 43.572 -26.677 6.268 1.00 27.82 ? 192 CYS B O 1 ATOM 4843 C CB . CYS B 1 192 ? 43.738 -24.587 4.314 1.00 27.85 ? 192 CYS B CB 1 ATOM 4844 S SG . CYS B 1 192 ? 44.493 -23.361 5.367 1.00 30.42 ? 192 CYS B SG 1 ATOM 4845 N N . THR B 1 193 ? 45.517 -27.561 5.588 1.00 28.64 ? 193 THR B N 1 ATOM 4846 C CA . THR B 1 193 ? 45.632 -28.505 6.714 1.00 29.44 ? 193 THR B CA 1 ATOM 4847 C C . THR B 1 193 ? 45.392 -27.924 8.120 1.00 28.35 ? 193 THR B C 1 ATOM 4848 O O . THR B 1 193 ? 44.696 -28.531 8.931 1.00 28.36 ? 193 THR B O 1 ATOM 4849 C CB . THR B 1 193 ? 47.014 -29.131 6.712 1.00 29.95 ? 193 THR B CB 1 ATOM 4850 O OG1 . THR B 1 193 ? 47.383 -29.412 5.365 1.00 31.26 ? 193 THR B OG1 1 ATOM 4851 C CG2 . THR B 1 193 ? 47.030 -30.415 7.530 1.00 32.13 ? 193 THR B CG2 1 ATOM 4852 N N . VAL B 1 194 ? 45.979 -26.763 8.404 1.00 27.94 ? 194 VAL B N 1 ATOM 4853 C CA . VAL B 1 194 ? 45.839 -26.171 9.728 1.00 27.21 ? 194 VAL B CA 1 ATOM 4854 C C . VAL B 1 194 ? 44.370 -25.803 9.975 1.00 28.06 ? 194 VAL B C 1 ATOM 4855 O O . VAL B 1 194 ? 43.843 -26.110 11.068 1.00 28.31 ? 194 VAL B O 1 ATOM 4856 C CB . VAL B 1 194 ? 46.859 -25.042 9.990 1.00 27.24 ? 194 VAL B CB 1 ATOM 4857 C CG1 . VAL B 1 194 ? 46.572 -24.323 11.321 1.00 26.81 ? 194 VAL B CG1 1 ATOM 4858 C CG2 . VAL B 1 194 ? 48.262 -25.622 10.025 1.00 26.07 ? 194 VAL B CG2 1 ATOM 4859 N N . PHE B 1 195 ? 43.704 -25.233 8.949 1.00 27.20 ? 195 PHE B N 1 ATOM 4860 C CA . PHE B 1 195 ? 42.300 -24.860 9.030 1.00 26.56 ? 195 PHE B CA 1 ATOM 4861 C C . PHE B 1 195 ? 41.376 -26.088 9.174 1.00 27.92 ? 195 PHE B C 1 ATOM 4862 O O . PHE B 1 195 ? 40.392 -26.086 9.946 1.00 27.14 ? 195 PHE B O 1 ATOM 4863 C CB . PHE B 1 195 ? 41.870 -23.973 7.841 1.00 25.80 ? 195 PHE B CB 1 ATOM 4864 C CG . PHE B 1 195 ? 40.393 -23.772 7.768 1.00 21.00 ? 195 PHE B CG 1 ATOM 4865 C CD1 . PHE B 1 195 ? 39.768 -22.846 8.608 1.00 19.66 ? 195 PHE B CD1 1 ATOM 4866 C CD2 . PHE B 1 195 ? 39.598 -24.576 6.939 1.00 16.82 ? 195 PHE B CD2 1 ATOM 4867 C CE1 . PHE B 1 195 ? 38.373 -22.674 8.599 1.00 13.51 ? 195 PHE B CE1 1 ATOM 4868 C CE2 . PHE B 1 195 ? 38.205 -24.421 6.928 1.00 12.78 ? 195 PHE B CE2 1 ATOM 4869 C CZ . PHE B 1 195 ? 37.608 -23.461 7.766 1.00 10.51 ? 195 PHE B CZ 1 ATOM 4870 N N . GLU B 1 196 ? 41.680 -27.138 8.424 1.00 29.29 ? 196 GLU B N 1 ATOM 4871 C CA . GLU B 1 196 ? 40.862 -28.348 8.517 1.00 31.03 ? 196 GLU B CA 1 ATOM 4872 C C . GLU B 1 196 ? 40.853 -28.920 9.951 1.00 32.10 ? 196 GLU B C 1 ATOM 4873 O O . GLU B 1 196 ? 39.893 -29.577 10.340 1.00 32.49 ? 196 GLU B O 1 ATOM 4874 C CB . GLU B 1 196 ? 41.302 -29.397 7.483 1.00 31.18 ? 196 GLU B CB 1 ATOM 4875 C CG . GLU B 1 196 ? 40.866 -29.083 6.005 1.00 30.80 ? 196 GLU B CG 1 ATOM 4876 C CD . GLU B 1 196 ? 39.367 -28.703 5.864 1.00 32.45 ? 196 GLU B CD 1 ATOM 4877 O OE1 . GLU B 1 196 ? 38.488 -29.359 6.511 1.00 31.79 ? 196 GLU B OE1 1 ATOM 4878 O OE2 . GLU B 1 196 ? 39.060 -27.744 5.100 1.00 30.78 ? 196 GLU B OE2 1 ATOM 4879 N N . ASP B 1 197 ? 41.920 -28.650 10.720 1.00 32.25 ? 197 ASP B N 1 ATOM 4880 C CA . ASP B 1 197 ? 42.086 -29.169 12.085 1.00 32.79 ? 197 ASP B CA 1 ATOM 4881 C C . ASP B 1 197 ? 41.500 -28.247 13.193 1.00 33.30 ? 197 ASP B C 1 ATOM 4882 O O . ASP B 1 197 ? 41.261 -28.710 14.316 1.00 33.92 ? 197 ASP B O 1 ATOM 4883 C CB . ASP B 1 197 ? 43.585 -29.405 12.385 1.00 33.20 ? 197 ASP B CB 1 ATOM 4884 C CG . ASP B 1 197 ? 44.146 -30.711 11.776 1.00 32.12 ? 197 ASP B CG 1 ATOM 4885 O OD1 . ASP B 1 197 ? 43.431 -31.496 11.153 1.00 32.35 ? 197 ASP B OD1 1 ATOM 4886 O OD2 . ASP B 1 197 ? 45.343 -30.959 11.927 1.00 31.90 ? 197 ASP B OD2 1 ATOM 4887 N N . SER B 1 198 ? 41.279 -26.965 12.880 1.00 32.96 ? 198 SER B N 1 ATOM 4888 C CA . SER B 1 198 ? 40.762 -25.965 13.836 1.00 32.94 ? 198 SER B CA 1 ATOM 4889 C C . SER B 1 198 ? 39.570 -26.457 14.670 1.00 33.48 ? 198 SER B C 1 ATOM 4890 O O . SER B 1 198 ? 38.701 -27.150 14.156 1.00 33.44 ? 198 SER B O 1 ATOM 4891 C CB . SER B 1 198 ? 40.372 -24.658 13.105 1.00 32.82 ? 198 SER B CB 1 ATOM 4892 O OG . SER B 1 198 ? 39.796 -23.695 13.986 1.00 30.63 ? 198 SER B OG 1 ATOM 4893 N N . GLU B 1 199 ? 39.533 -26.071 15.945 1.00 33.68 ? 199 GLU B N 1 ATOM 4894 C CA . GLU B 1 199 ? 38.444 -26.475 16.831 1.00 34.31 ? 199 GLU B CA 1 ATOM 4895 C C . GLU B 1 199 ? 37.870 -25.248 17.540 1.00 33.12 ? 199 GLU B C 1 ATOM 4896 O O . GLU B 1 199 ? 37.131 -25.376 18.513 1.00 34.04 ? 199 GLU B O 1 ATOM 4897 C CB . GLU B 1 199 ? 38.900 -27.580 17.835 1.00 35.25 ? 199 GLU B CB 1 ATOM 4898 C CG . GLU B 1 199 ? 39.519 -28.840 17.169 1.00 39.35 ? 199 GLU B CG 1 ATOM 4899 C CD . GLU B 1 199 ? 40.153 -29.876 18.155 1.00 46.38 ? 199 GLU B CD 1 ATOM 4900 O OE1 . GLU B 1 199 ? 41.095 -29.521 18.925 1.00 47.33 ? 199 GLU B OE1 1 ATOM 4901 O OE2 . GLU B 1 199 ? 39.723 -31.065 18.126 1.00 47.01 ? 199 GLU B OE2 1 ATOM 4902 N N . LEU B 1 200 ? 38.198 -24.056 17.044 1.00 32.12 ? 200 LEU B N 1 ATOM 4903 C CA . LEU B 1 200 ? 37.650 -22.804 17.588 1.00 30.72 ? 200 LEU B CA 1 ATOM 4904 C C . LEU B 1 200 ? 36.092 -22.754 17.598 1.00 30.66 ? 200 LEU B C 1 ATOM 4905 O O . LEU B 1 200 ? 35.486 -22.387 18.613 1.00 30.83 ? 200 LEU B O 1 ATOM 4906 C CB . LEU B 1 200 ? 38.283 -21.592 16.871 1.00 30.29 ? 200 LEU B CB 1 ATOM 4907 C CG . LEU B 1 200 ? 37.882 -20.127 17.210 1.00 30.65 ? 200 LEU B CG 1 ATOM 4908 C CD1 . LEU B 1 200 ? 37.952 -19.807 18.682 1.00 28.67 ? 200 LEU B CD1 1 ATOM 4909 C CD2 . LEU B 1 200 ? 38.740 -19.138 16.460 1.00 27.55 ? 200 LEU B CD2 1 ATOM 4910 N N . ALA B 1 201 ? 35.460 -23.132 16.486 1.00 29.81 ? 201 ALA B N 1 ATOM 4911 C CA . ALA B 1 201 ? 33.995 -23.180 16.374 1.00 30.04 ? 201 ALA B CA 1 ATOM 4912 C C . ALA B 1 201 ? 33.293 -24.028 17.445 1.00 29.77 ? 201 ALA B C 1 ATOM 4913 O O . ALA B 1 201 ? 32.330 -23.584 18.055 1.00 28.89 ? 201 ALA B O 1 ATOM 4914 C CB . ALA B 1 201 ? 33.578 -23.642 14.951 1.00 29.71 ? 201 ALA B CB 1 ATOM 4915 N N . ASP B 1 202 ? 33.783 -25.254 17.658 1.00 30.66 ? 202 ASP B N 1 ATOM 4916 C CA . ASP B 1 202 ? 33.323 -26.124 18.757 1.00 31.25 ? 202 ASP B CA 1 ATOM 4917 C C . ASP B 1 202 ? 33.391 -25.451 20.127 1.00 31.24 ? 202 ASP B C 1 ATOM 4918 O O . ASP B 1 202 ? 32.460 -25.531 20.950 1.00 30.97 ? 202 ASP B O 1 ATOM 4919 C CB . ASP B 1 202 ? 34.168 -27.379 18.803 1.00 31.83 ? 202 ASP B CB 1 ATOM 4920 C CG . ASP B 1 202 ? 33.889 -28.291 17.668 1.00 34.17 ? 202 ASP B CG 1 ATOM 4921 O OD1 . ASP B 1 202 ? 32.738 -28.283 17.220 1.00 37.68 ? 202 ASP B OD1 1 ATOM 4922 O OD2 . ASP B 1 202 ? 34.802 -29.031 17.235 1.00 38.37 ? 202 ASP B OD2 1 ATOM 4923 N N . THR B 1 203 ? 34.513 -24.798 20.389 1.00 31.58 ? 203 THR B N 1 ATOM 4924 C CA . THR B 1 203 ? 34.676 -24.150 21.686 1.00 31.36 ? 203 THR B CA 1 ATOM 4925 C C . THR B 1 203 ? 33.568 -23.131 21.889 1.00 31.33 ? 203 THR B C 1 ATOM 4926 O O . THR B 1 203 ? 32.810 -23.234 22.862 1.00 31.55 ? 203 THR B O 1 ATOM 4927 C CB . THR B 1 203 ? 36.093 -23.652 21.883 1.00 30.82 ? 203 THR B CB 1 ATOM 4928 O OG1 . THR B 1 203 ? 36.940 -24.797 21.795 1.00 31.43 ? 203 THR B OG1 1 ATOM 4929 C CG2 . THR B 1 203 ? 36.292 -23.082 23.275 1.00 31.77 ? 203 THR B CG2 1 ATOM 4930 N N . VAL B 1 204 ? 33.414 -22.218 20.928 1.00 31.30 ? 204 VAL B N 1 ATOM 4931 C CA . VAL B 1 204 ? 32.334 -21.212 20.962 1.00 30.82 ? 204 VAL B CA 1 ATOM 4932 C C . VAL B 1 204 ? 30.933 -21.820 20.987 1.00 30.33 ? 204 VAL B C 1 ATOM 4933 O O . VAL B 1 204 ? 30.040 -21.267 21.615 1.00 30.07 ? 204 VAL B O 1 ATOM 4934 C CB . VAL B 1 204 ? 32.398 -20.256 19.762 1.00 31.24 ? 204 VAL B CB 1 ATOM 4935 C CG1 . VAL B 1 204 ? 31.349 -19.141 19.925 1.00 31.32 ? 204 VAL B CG1 1 ATOM 4936 C CG2 . VAL B 1 204 ? 33.831 -19.672 19.579 1.00 30.19 ? 204 VAL B CG2 1 ATOM 4937 N N . GLU B 1 205 ? 30.738 -22.938 20.283 1.00 29.96 ? 205 GLU B N 1 ATOM 4938 C CA . GLU B 1 205 ? 29.429 -23.560 20.234 1.00 29.21 ? 205 GLU B CA 1 ATOM 4939 C C . GLU B 1 205 ? 29.147 -24.054 21.628 1.00 29.22 ? 205 GLU B C 1 ATOM 4940 O O . GLU B 1 205 ? 28.072 -23.795 22.150 1.00 29.21 ? 205 GLU B O 1 ATOM 4941 C CB . GLU B 1 205 ? 29.342 -24.712 19.222 1.00 28.96 ? 205 GLU B CB 1 ATOM 4942 C CG . GLU B 1 205 ? 27.989 -25.494 19.291 1.00 28.91 ? 205 GLU B CG 1 ATOM 4943 C CD . GLU B 1 205 ? 27.808 -26.658 18.258 1.00 29.24 ? 205 GLU B CD 1 ATOM 4944 O OE1 . GLU B 1 205 ? 28.721 -27.009 17.482 1.00 30.35 ? 205 GLU B OE1 1 ATOM 4945 O OE2 . GLU B 1 205 ? 26.699 -27.226 18.216 1.00 31.25 ? 205 GLU B OE2 1 ATOM 4946 N N . ALA B 1 206 ? 30.109 -24.739 22.253 1.00 29.20 ? 206 ALA B N 1 ATOM 4947 C CA . ALA B 1 206 ? 29.874 -25.274 23.621 1.00 28.88 ? 206 ALA B CA 1 ATOM 4948 C C . ALA B 1 206 ? 29.684 -24.148 24.619 1.00 28.85 ? 206 ALA B C 1 ATOM 4949 O O . ALA B 1 206 ? 28.714 -24.145 25.381 1.00 28.68 ? 206 ALA B O 1 ATOM 4950 C CB . ALA B 1 206 ? 30.978 -26.199 24.063 1.00 28.51 ? 206 ALA B CB 1 ATOM 4951 N N . ASN B 1 207 ? 30.569 -23.159 24.570 1.00 28.94 ? 207 ASN B N 1 ATOM 4952 C CA . ASN B 1 207 ? 30.469 -22.042 25.484 1.00 29.59 ? 207 ASN B CA 1 ATOM 4953 C C . ASN B 1 207 ? 29.133 -21.315 25.433 1.00 29.57 ? 207 ASN B C 1 ATOM 4954 O O . ASN B 1 207 ? 28.560 -21.031 26.486 1.00 29.78 ? 207 ASN B O 1 ATOM 4955 C CB . ASN B 1 207 ? 31.676 -21.102 25.357 1.00 29.87 ? 207 ASN B CB 1 ATOM 4956 C CG . ASN B 1 207 ? 32.993 -21.725 25.932 1.00 32.99 ? 207 ASN B CG 1 ATOM 4957 O OD1 . ASN B 1 207 ? 33.088 -22.944 26.216 1.00 34.12 ? 207 ASN B OD1 1 ATOM 4958 N ND2 . ASN B 1 207 ? 34.008 -20.874 26.109 1.00 33.51 ? 207 ASN B ND2 1 ATOM 4959 N N . PHE B 1 208 ? 28.609 -21.041 24.229 1.00 29.87 ? 208 PHE B N 1 ATOM 4960 C CA . PHE B 1 208 ? 27.368 -20.235 24.101 1.00 29.03 ? 208 PHE B CA 1 ATOM 4961 C C . PHE B 1 208 ? 26.140 -21.080 24.351 1.00 29.43 ? 208 PHE B C 1 ATOM 4962 O O . PHE B 1 208 ? 25.133 -20.558 24.810 1.00 28.80 ? 208 PHE B O 1 ATOM 4963 C CB . PHE B 1 208 ? 27.259 -19.499 22.757 1.00 29.03 ? 208 PHE B CB 1 ATOM 4964 C CG . PHE B 1 208 ? 25.973 -18.700 22.582 1.00 28.17 ? 208 PHE B CG 1 ATOM 4965 C CD1 . PHE B 1 208 ? 25.835 -17.414 23.128 1.00 29.14 ? 208 PHE B CD1 1 ATOM 4966 C CD2 . PHE B 1 208 ? 24.910 -19.216 21.849 1.00 27.44 ? 208 PHE B CD2 1 ATOM 4967 C CE1 . PHE B 1 208 ? 24.652 -16.665 22.957 1.00 27.43 ? 208 PHE B CE1 1 ATOM 4968 C CE2 . PHE B 1 208 ? 23.718 -18.484 21.669 1.00 25.85 ? 208 PHE B CE2 1 ATOM 4969 C CZ . PHE B 1 208 ? 23.596 -17.202 22.222 1.00 27.49 ? 208 PHE B CZ 1 ATOM 4970 N N . THR B 1 209 ? 26.225 -22.377 24.083 1.00 29.71 ? 209 THR B N 1 ATOM 4971 C CA . THR B 1 209 ? 25.095 -23.224 24.364 1.00 31.65 ? 209 THR B CA 1 ATOM 4972 C C . THR B 1 209 ? 24.904 -23.452 25.853 1.00 32.23 ? 209 THR B C 1 ATOM 4973 O O . THR B 1 209 ? 23.829 -23.875 26.285 1.00 33.21 ? 209 THR B O 1 ATOM 4974 C CB . THR B 1 209 ? 25.150 -24.615 23.695 1.00 31.40 ? 209 THR B CB 1 ATOM 4975 O OG1 . THR B 1 209 ? 26.326 -25.289 24.097 1.00 35.14 ? 209 THR B OG1 1 ATOM 4976 C CG2 . THR B 1 209 ? 25.120 -24.533 22.202 1.00 31.53 ? 209 THR B CG2 1 ATOM 4977 N N . ALA B 1 210 ? 25.942 -23.177 26.635 1.00 33.10 ? 210 ALA B N 1 ATOM 4978 C CA . ALA B 1 210 ? 25.887 -23.341 28.090 1.00 33.10 ? 210 ALA B CA 1 ATOM 4979 C C . ALA B 1 210 ? 25.141 -22.178 28.725 1.00 33.62 ? 210 ALA B C 1 ATOM 4980 O O . ALA B 1 210 ? 24.741 -22.241 29.891 1.00 33.61 ? 210 ALA B O 1 ATOM 4981 C CB . ALA B 1 210 ? 27.292 -23.476 28.677 1.00 32.82 ? 210 ALA B CB 1 ATOM 4982 N N . THR B 1 211 ? 24.942 -21.118 27.952 1.00 33.79 ? 211 THR B N 1 ATOM 4983 C CA . THR B 1 211 ? 24.306 -19.936 28.486 1.00 34.36 ? 211 THR B CA 1 ATOM 4984 C C . THR B 1 211 ? 22.789 -19.924 28.290 1.00 34.49 ? 211 THR B C 1 ATOM 4985 O O . THR B 1 211 ? 22.114 -19.032 28.838 1.00 34.40 ? 211 THR B O 1 ATOM 4986 C CB . THR B 1 211 ? 24.852 -18.660 27.821 1.00 34.89 ? 211 THR B CB 1 ATOM 4987 O OG1 . THR B 1 211 ? 24.458 -18.643 26.445 1.00 35.76 ? 211 THR B OG1 1 ATOM 4988 C CG2 . THR B 1 211 ? 26.401 -18.586 27.916 1.00 35.98 ? 211 THR B CG2 1 ATOM 4989 N N . PHE B 1 212 ? 22.254 -20.858 27.484 1.00 33.83 ? 212 PHE B N 1 ATOM 4990 C CA . PHE B 1 212 ? 20.823 -20.791 27.156 1.00 33.27 ? 212 PHE B CA 1 ATOM 4991 C C . PHE B 1 212 ? 20.092 -22.115 27.024 1.00 32.07 ? 212 PHE B C 1 ATOM 4992 O O . PHE B 1 212 ? 18.896 -22.176 27.292 1.00 31.65 ? 212 PHE B O 1 ATOM 4993 C CB . PHE B 1 212 ? 20.560 -19.902 25.928 1.00 33.54 ? 212 PHE B CB 1 ATOM 4994 C CG . PHE B 1 212 ? 20.655 -20.622 24.608 1.00 34.24 ? 212 PHE B CG 1 ATOM 4995 C CD1 . PHE B 1 212 ? 21.861 -20.691 23.926 1.00 31.91 ? 212 PHE B CD1 1 ATOM 4996 C CD2 . PHE B 1 212 ? 19.516 -21.186 24.030 1.00 34.67 ? 212 PHE B CD2 1 ATOM 4997 C CE1 . PHE B 1 212 ? 21.939 -21.335 22.713 1.00 32.97 ? 212 PHE B CE1 1 ATOM 4998 C CE2 . PHE B 1 212 ? 19.576 -21.827 22.807 1.00 34.42 ? 212 PHE B CE2 1 ATOM 4999 C CZ . PHE B 1 212 ? 20.794 -21.909 22.141 1.00 34.12 ? 212 PHE B CZ 1 ATOM 5000 N N . VAL B 1 213 ? 20.802 -23.156 26.617 1.00 31.26 ? 213 VAL B N 1 ATOM 5001 C CA . VAL B 1 213 ? 20.188 -24.477 26.492 1.00 31.05 ? 213 VAL B CA 1 ATOM 5002 C C . VAL B 1 213 ? 19.753 -25.186 27.806 1.00 31.04 ? 213 VAL B C 1 ATOM 5003 O O . VAL B 1 213 ? 18.680 -25.781 27.820 1.00 30.90 ? 213 VAL B O 1 ATOM 5004 C CB . VAL B 1 213 ? 20.998 -25.378 25.559 1.00 31.26 ? 213 VAL B CB 1 ATOM 5005 C CG1 . VAL B 1 213 ? 20.506 -26.840 25.582 1.00 31.02 ? 213 VAL B CG1 1 ATOM 5006 C CG2 . VAL B 1 213 ? 20.935 -24.815 24.162 1.00 31.14 ? 213 VAL B CG2 1 ATOM 5007 N N . PRO B 1 214 ? 20.557 -25.103 28.906 1.00 30.98 ? 214 PRO B N 1 ATOM 5008 C CA . PRO B 1 214 ? 20.140 -25.674 30.224 1.00 30.39 ? 214 PRO B CA 1 ATOM 5009 C C . PRO B 1 214 ? 18.694 -25.368 30.687 1.00 29.87 ? 214 PRO B C 1 ATOM 5010 O O . PRO B 1 214 ? 18.012 -26.257 31.153 1.00 29.42 ? 214 PRO B O 1 ATOM 5011 C CB . PRO B 1 214 ? 21.136 -25.047 31.211 1.00 30.00 ? 214 PRO B CB 1 ATOM 5012 C CG . PRO B 1 214 ? 22.400 -24.864 30.388 1.00 31.34 ? 214 PRO B CG 1 ATOM 5013 C CD . PRO B 1 214 ? 21.890 -24.452 28.997 1.00 31.30 ? 214 PRO B CD 1 ATOM 5014 N N . SER B 1 215 ? 18.243 -24.125 30.547 1.00 29.98 ? 215 SER B N 1 ATOM 5015 C CA . SER B 1 215 ? 16.897 -23.729 30.941 1.00 30.49 ? 215 SER B CA 1 ATOM 5016 C C . SER B 1 215 ? 15.868 -24.448 30.113 1.00 30.47 ? 215 SER B C 1 ATOM 5017 O O . SER B 1 215 ? 14.747 -24.633 30.558 1.00 30.72 ? 215 SER B O 1 ATOM 5018 C CB . SER B 1 215 ? 16.672 -22.235 30.706 1.00 30.57 ? 215 SER B CB 1 ATOM 5019 O OG . SER B 1 215 ? 17.728 -21.468 31.251 1.00 32.93 ? 215 SER B OG 1 ATOM 5020 N N . ILE B 1 216 ? 16.237 -24.801 28.891 1.00 30.19 ? 216 ILE B N 1 ATOM 5021 C CA . ILE B 1 216 ? 15.311 -25.444 27.982 1.00 30.36 ? 216 ILE B CA 1 ATOM 5022 C C . ILE B 1 216 ? 15.279 -26.898 28.377 1.00 30.32 ? 216 ILE B C 1 ATOM 5023 O O . ILE B 1 216 ? 14.195 -27.464 28.581 1.00 30.94 ? 216 ILE B O 1 ATOM 5024 C CB . ILE B 1 216 ? 15.713 -25.249 26.476 1.00 30.34 ? 216 ILE B CB 1 ATOM 5025 C CG1 . ILE B 1 216 ? 15.768 -23.766 26.107 1.00 30.07 ? 216 ILE B CG1 1 ATOM 5026 C CG2 . ILE B 1 216 ? 14.719 -25.920 25.566 1.00 29.83 ? 216 ILE B CG2 1 ATOM 5027 C CD1 . ILE B 1 216 ? 16.497 -23.486 24.797 1.00 31.47 ? 216 ILE B CD1 1 ATOM 5028 N N . ARG B 1 217 ? 16.472 -27.479 28.540 1.00 29.92 ? 217 ARG B N 1 ATOM 5029 C CA . ARG B 1 217 ? 16.622 -28.845 29.043 1.00 29.76 ? 217 ARG B CA 1 ATOM 5030 C C . ARG B 1 217 ? 15.784 -29.097 30.303 1.00 29.65 ? 217 ARG B C 1 ATOM 5031 O O . ARG B 1 217 ? 15.091 -30.085 30.387 1.00 29.34 ? 217 ARG B O 1 ATOM 5032 C CB . ARG B 1 217 ? 18.089 -29.167 29.311 1.00 29.81 ? 217 ARG B CB 1 ATOM 5033 C CG . ARG B 1 217 ? 18.303 -30.640 29.728 1.00 31.61 ? 217 ARG B CG 1 ATOM 5034 C CD . ARG B 1 217 ? 19.572 -30.895 30.499 1.00 32.45 ? 217 ARG B CD 1 ATOM 5035 N NE . ARG B 1 217 ? 19.983 -29.817 31.416 1.00 34.43 ? 217 ARG B NE 1 ATOM 5036 C CZ . ARG B 1 217 ? 19.564 -29.669 32.682 1.00 30.65 ? 217 ARG B CZ 1 ATOM 5037 N NH1 . ARG B 1 217 ? 18.691 -30.500 33.215 1.00 26.20 ? 217 ARG B NH1 1 ATOM 5038 N NH2 . ARG B 1 217 ? 20.013 -28.653 33.410 1.00 27.80 ? 217 ARG B NH2 1 ATOM 5039 N N . GLN B 1 218 ? 15.843 -28.191 31.264 1.00 29.94 ? 218 GLN B N 1 ATOM 5040 C CA . GLN B 1 218 ? 15.138 -28.373 32.530 1.00 31.31 ? 218 GLN B CA 1 ATOM 5041 C C . GLN B 1 218 ? 13.658 -28.489 32.243 1.00 30.99 ? 218 GLN B C 1 ATOM 5042 O O . GLN B 1 218 ? 13.032 -29.505 32.572 1.00 30.29 ? 218 GLN B O 1 ATOM 5043 C CB . GLN B 1 218 ? 15.368 -27.181 33.444 1.00 31.34 ? 218 GLN B CB 1 ATOM 5044 C CG . GLN B 1 218 ? 15.289 -27.471 34.942 1.00 33.51 ? 218 GLN B CG 1 ATOM 5045 C CD . GLN B 1 218 ? 16.190 -26.495 35.722 1.00 35.96 ? 218 GLN B CD 1 ATOM 5046 O OE1 . GLN B 1 218 ? 16.160 -25.272 35.510 1.00 35.62 ? 218 GLN B OE1 1 ATOM 5047 N NE2 . GLN B 1 218 ? 17.039 -27.047 36.568 1.00 35.82 ? 218 GLN B NE2 1 ATOM 5048 N N . ARG B 1 219 ? 13.135 -27.451 31.585 1.00 31.10 ? 219 ARG B N 1 ATOM 5049 C CA . ARG B 1 219 ? 11.737 -27.395 31.199 1.00 31.42 ? 219 ARG B CA 1 ATOM 5050 C C . ARG B 1 219 ? 11.300 -28.650 30.466 1.00 31.95 ? 219 ARG B C 1 ATOM 5051 O O . ARG B 1 219 ? 10.277 -29.233 30.813 1.00 32.68 ? 219 ARG B O 1 ATOM 5052 C CB . ARG B 1 219 ? 11.404 -26.142 30.387 1.00 30.73 ? 219 ARG B CB 1 ATOM 5053 C CG . ARG B 1 219 ? 9.889 -25.979 30.210 1.00 31.03 ? 219 ARG B CG 1 ATOM 5054 C CD . ARG B 1 219 ? 9.487 -24.796 29.331 1.00 32.12 ? 219 ARG B CD 1 ATOM 5055 N NE . ARG B 1 219 ? 9.959 -24.892 27.944 1.00 31.33 ? 219 ARG B NE 1 ATOM 5056 C CZ . ARG B 1 219 ? 10.854 -24.077 27.390 1.00 31.67 ? 219 ARG B CZ 1 ATOM 5057 N NH1 . ARG B 1 219 ? 11.416 -23.090 28.076 1.00 31.27 ? 219 ARG B NH1 1 ATOM 5058 N NH2 . ARG B 1 219 ? 11.178 -24.235 26.126 1.00 32.19 ? 219 ARG B NH2 1 ATOM 5059 N N . LEU B 1 220 ? 12.080 -29.089 29.478 1.00 32.77 ? 220 LEU B N 1 ATOM 5060 C CA . LEU B 1 220 ? 11.716 -30.304 28.730 1.00 33.62 ? 220 LEU B CA 1 ATOM 5061 C C . LEU B 1 220 ? 11.735 -31.593 29.548 1.00 33.76 ? 220 LEU B C 1 ATOM 5062 O O . LEU B 1 220 ? 10.939 -32.473 29.294 1.00 34.04 ? 220 LEU B O 1 ATOM 5063 C CB . LEU B 1 220 ? 12.588 -30.487 27.487 1.00 33.68 ? 220 LEU B CB 1 ATOM 5064 C CG . LEU B 1 220 ? 12.570 -29.506 26.327 1.00 34.20 ? 220 LEU B CG 1 ATOM 5065 C CD1 . LEU B 1 220 ? 13.620 -29.979 25.273 1.00 32.01 ? 220 LEU B CD1 1 ATOM 5066 C CD2 . LEU B 1 220 ? 11.167 -29.405 25.766 1.00 32.83 ? 220 LEU B CD2 1 ATOM 5067 N N . GLU B 1 221 ? 12.663 -31.724 30.488 1.00 34.70 ? 221 GLU B N 1 ATOM 5068 C CA . GLU B 1 221 ? 12.676 -32.899 31.366 1.00 35.86 ? 221 GLU B CA 1 ATOM 5069 C C . GLU B 1 221 ? 11.532 -32.789 32.359 1.00 36.31 ? 221 GLU B C 1 ATOM 5070 O O . GLU B 1 221 ? 10.943 -33.788 32.742 1.00 36.27 ? 221 GLU B O 1 ATOM 5071 C CB . GLU B 1 221 ? 13.996 -33.036 32.120 1.00 35.70 ? 221 GLU B CB 1 ATOM 5072 C CG . GLU B 1 221 ? 15.158 -33.615 31.299 1.00 36.34 ? 221 GLU B CG 1 ATOM 5073 C CD . GLU B 1 221 ? 16.507 -33.471 31.991 1.00 36.52 ? 221 GLU B CD 1 ATOM 5074 O OE1 . GLU B 1 221 ? 16.675 -32.587 32.842 1.00 39.25 ? 221 GLU B OE1 1 ATOM 5075 O OE2 . GLU B 1 221 ? 17.414 -34.240 31.695 1.00 36.71 ? 221 GLU B OE2 1 ATOM 5076 N N . ASN B 1 222 ? 11.226 -31.560 32.750 1.00 36.99 ? 222 ASN B N 1 ATOM 5077 C CA . ASN B 1 222 ? 10.124 -31.275 33.637 1.00 38.22 ? 222 ASN B CA 1 ATOM 5078 C C . ASN B 1 222 ? 8.787 -31.689 33.062 1.00 38.20 ? 222 ASN B C 1 ATOM 5079 O O . ASN B 1 222 ? 7.958 -32.254 33.776 1.00 38.00 ? 222 ASN B O 1 ATOM 5080 C CB . ASN B 1 222 ? 10.076 -29.792 33.888 1.00 38.82 ? 222 ASN B CB 1 ATOM 5081 C CG . ASN B 1 222 ? 10.129 -29.464 35.351 1.00 43.11 ? 222 ASN B CG 1 ATOM 5082 O OD1 . ASN B 1 222 ? 9.078 -29.217 35.986 1.00 46.69 ? 222 ASN B OD1 1 ATOM 5083 N ND2 . ASN B 1 222 ? 11.350 -29.487 35.923 1.00 43.65 ? 222 ASN B ND2 1 ATOM 5084 N N . ASP B 1 223 ? 8.597 -31.391 31.770 1.00 38.10 ? 223 ASP B N 1 ATOM 5085 C CA . ASP B 1 223 ? 7.348 -31.638 31.059 1.00 38.08 ? 223 ASP B CA 1 ATOM 5086 C C . ASP B 1 223 ? 7.228 -33.087 30.599 1.00 37.94 ? 223 ASP B C 1 ATOM 5087 O O . ASP B 1 223 ? 6.135 -33.623 30.485 1.00 38.25 ? 223 ASP B O 1 ATOM 5088 C CB . ASP B 1 223 ? 7.244 -30.705 29.861 1.00 38.07 ? 223 ASP B CB 1 ATOM 5089 C CG . ASP B 1 223 ? 7.061 -29.252 30.264 1.00 39.22 ? 223 ASP B CG 1 ATOM 5090 O OD1 . ASP B 1 223 ? 6.466 -29.002 31.327 1.00 41.10 ? 223 ASP B OD1 1 ATOM 5091 O OD2 . ASP B 1 223 ? 7.487 -28.348 29.520 1.00 39.40 ? 223 ASP B OD2 1 ATOM 5092 N N . LEU B 1 224 ? 8.362 -33.712 30.328 1.00 37.65 ? 224 LEU B N 1 ATOM 5093 C CA . LEU B 1 224 ? 8.378 -35.082 29.857 1.00 37.46 ? 224 LEU B CA 1 ATOM 5094 C C . LEU B 1 224 ? 9.002 -35.981 30.937 1.00 37.51 ? 224 LEU B C 1 ATOM 5095 O O . LEU B 1 224 ? 10.175 -36.357 30.850 1.00 37.77 ? 224 LEU B O 1 ATOM 5096 C CB . LEU B 1 224 ? 9.138 -35.171 28.521 1.00 37.48 ? 224 LEU B CB 1 ATOM 5097 C CG . LEU B 1 224 ? 8.481 -34.626 27.232 1.00 37.35 ? 224 LEU B CG 1 ATOM 5098 C CD1 . LEU B 1 224 ? 9.538 -34.057 26.265 1.00 36.03 ? 224 LEU B CD1 1 ATOM 5099 C CD2 . LEU B 1 224 ? 7.619 -35.716 26.538 1.00 35.39 ? 224 LEU B CD2 1 ATOM 5100 N N . SER B 1 225 ? 8.202 -36.308 31.950 1.00 37.41 ? 225 SER B N 1 ATOM 5101 C CA . SER B 1 225 ? 8.610 -37.141 33.093 1.00 37.41 ? 225 SER B CA 1 ATOM 5102 C C . SER B 1 225 ? 9.225 -38.493 32.746 1.00 37.00 ? 225 SER B C 1 ATOM 5103 O O . SER B 1 225 ? 8.553 -39.374 32.182 1.00 37.48 ? 225 SER B O 1 ATOM 5104 C CB . SER B 1 225 ? 7.414 -37.368 34.013 1.00 37.59 ? 225 SER B CB 1 ATOM 5105 O OG . SER B 1 225 ? 7.237 -36.237 34.846 1.00 39.69 ? 225 SER B OG 1 ATOM 5106 N N . GLY B 1 226 ? 10.496 -38.670 33.097 1.00 36.44 ? 226 GLY B N 1 ATOM 5107 C CA . GLY B 1 226 ? 11.156 -39.965 32.882 1.00 36.43 ? 226 GLY B CA 1 ATOM 5108 C C . GLY B 1 226 ? 12.239 -39.866 31.824 1.00 35.91 ? 226 GLY B C 1 ATOM 5109 O O . GLY B 1 226 ? 12.971 -40.831 31.555 1.00 36.15 ? 226 GLY B O 1 ATOM 5110 N N . VAL B 1 227 ? 12.352 -38.664 31.264 1.00 34.94 ? 227 VAL B N 1 ATOM 5111 C CA . VAL B 1 227 ? 13.270 -38.371 30.172 1.00 33.88 ? 227 VAL B CA 1 ATOM 5112 C C . VAL B 1 227 ? 14.455 -37.605 30.706 1.00 33.16 ? 227 VAL B C 1 ATOM 5113 O O . VAL B 1 227 ? 14.275 -36.720 31.511 1.00 32.57 ? 227 VAL B O 1 ATOM 5114 C CB . VAL B 1 227 ? 12.533 -37.543 29.109 1.00 33.27 ? 227 VAL B CB 1 ATOM 5115 C CG1 . VAL B 1 227 ? 13.442 -36.630 28.415 1.00 33.85 ? 227 VAL B CG1 1 ATOM 5116 C CG2 . VAL B 1 227 ? 11.824 -38.483 28.141 1.00 33.10 ? 227 VAL B CG2 1 ATOM 5117 N N . THR B 1 228 ? 15.667 -37.929 30.260 1.00 32.85 ? 228 THR B N 1 ATOM 5118 C CA . THR B 1 228 ? 16.831 -37.192 30.729 1.00 32.65 ? 228 THR B CA 1 ATOM 5119 C C . THR B 1 228 ? 17.648 -36.797 29.509 1.00 32.25 ? 228 THR B C 1 ATOM 5120 O O . THR B 1 228 ? 18.021 -37.644 28.716 1.00 32.78 ? 228 THR B O 1 ATOM 5121 C CB . THR B 1 228 ? 17.658 -37.980 31.825 1.00 32.95 ? 228 THR B CB 1 ATOM 5122 O OG1 . THR B 1 228 ? 18.800 -38.636 31.245 1.00 33.51 ? 228 THR B OG1 1 ATOM 5123 C CG2 . THR B 1 228 ? 16.794 -39.033 32.547 1.00 33.10 ? 228 THR B CG2 1 ATOM 5124 N N . LEU B 1 229 ? 17.902 -35.504 29.343 1.00 31.90 ? 229 LEU B N 1 ATOM 5125 C CA . LEU B 1 229 ? 18.425 -34.959 28.068 1.00 31.85 ? 229 LEU B CA 1 ATOM 5126 C C . LEU B 1 229 ? 19.797 -34.289 28.197 1.00 32.03 ? 229 LEU B C 1 ATOM 5127 O O . LEU B 1 229 ? 20.075 -33.650 29.237 1.00 32.20 ? 229 LEU B O 1 ATOM 5128 C CB . LEU B 1 229 ? 17.429 -33.929 27.497 1.00 31.10 ? 229 LEU B CB 1 ATOM 5129 C CG . LEU B 1 229 ? 16.094 -34.435 26.932 1.00 31.21 ? 229 LEU B CG 1 ATOM 5130 C CD1 . LEU B 1 229 ? 15.070 -33.299 26.745 1.00 29.63 ? 229 LEU B CD1 1 ATOM 5131 C CD2 . LEU B 1 229 ? 16.272 -35.235 25.620 1.00 28.39 ? 229 LEU B CD2 1 ATOM 5132 N N . THR B 1 230 ? 20.644 -34.428 27.170 1.00 31.71 ? 230 THR B N 1 ATOM 5133 C CA . THR B 1 230 ? 21.888 -33.616 27.104 1.00 31.82 ? 230 THR B CA 1 ATOM 5134 C C . THR B 1 230 ? 21.641 -32.324 26.348 1.00 31.98 ? 230 THR B C 1 ATOM 5135 O O . THR B 1 230 ? 20.760 -32.253 25.518 1.00 32.59 ? 230 THR B O 1 ATOM 5136 C CB . THR B 1 230 ? 23.052 -34.321 26.405 1.00 31.67 ? 230 THR B CB 1 ATOM 5137 O OG1 . THR B 1 230 ? 22.744 -34.490 25.010 1.00 30.77 ? 230 THR B OG1 1 ATOM 5138 C CG2 . THR B 1 230 ? 23.394 -35.677 27.083 1.00 30.75 ? 230 THR B CG2 1 ATOM 5139 N N . ASP B 1 231 ? 22.421 -31.298 26.627 1.00 32.28 ? 231 ASP B N 1 ATOM 5140 C CA . ASP B 1 231 ? 22.278 -30.053 25.893 1.00 32.69 ? 231 ASP B CA 1 ATOM 5141 C C . ASP B 1 231 ? 22.290 -30.290 24.383 1.00 32.47 ? 231 ASP B C 1 ATOM 5142 O O . ASP B 1 231 ? 21.571 -29.614 23.621 1.00 33.21 ? 231 ASP B O 1 ATOM 5143 C CB . ASP B 1 231 ? 23.369 -29.084 26.304 1.00 33.03 ? 231 ASP B CB 1 ATOM 5144 C CG . ASP B 1 231 ? 23.225 -28.633 27.768 1.00 34.85 ? 231 ASP B CG 1 ATOM 5145 O OD1 . ASP B 1 231 ? 22.133 -28.803 28.365 1.00 37.19 ? 231 ASP B OD1 1 ATOM 5146 O OD2 . ASP B 1 231 ? 24.197 -28.092 28.334 1.00 35.78 ? 231 ASP B OD2 1 ATOM 5147 N N . THR B 1 232 ? 23.052 -31.287 23.947 1.00 31.03 ? 232 THR B N 1 ATOM 5148 C CA . THR B 1 232 ? 23.182 -31.509 22.521 1.00 29.90 ? 232 THR B CA 1 ATOM 5149 C C . THR B 1 232 ? 21.869 -32.020 21.985 1.00 29.11 ? 232 THR B C 1 ATOM 5150 O O . THR B 1 232 ? 21.353 -31.528 20.965 1.00 29.80 ? 232 THR B O 1 ATOM 5151 C CB . THR B 1 232 ? 24.397 -32.376 22.195 1.00 29.80 ? 232 THR B CB 1 ATOM 5152 O OG1 . THR B 1 232 ? 25.580 -31.612 22.484 1.00 30.20 ? 232 THR B OG1 1 ATOM 5153 C CG2 . THR B 1 232 ? 24.425 -32.728 20.731 1.00 30.22 ? 232 THR B CG2 1 ATOM 5154 N N . GLU B 1 233 ? 21.282 -32.951 22.724 1.00 27.61 ? 233 GLU B N 1 ATOM 5155 C CA . GLU B 1 233 ? 20.006 -33.506 22.337 1.00 26.50 ? 233 GLU B CA 1 ATOM 5156 C C . GLU B 1 233 ? 18.949 -32.424 22.227 1.00 25.77 ? 233 GLU B C 1 ATOM 5157 O O . GLU B 1 233 ? 18.122 -32.472 21.345 1.00 25.59 ? 233 GLU B O 1 ATOM 5158 C CB . GLU B 1 233 ? 19.606 -34.636 23.281 1.00 26.54 ? 233 GLU B CB 1 ATOM 5159 C CG . GLU B 1 233 ? 20.448 -35.929 22.989 1.00 28.26 ? 233 GLU B CG 1 ATOM 5160 C CD . GLU B 1 233 ? 20.504 -36.946 24.128 1.00 28.61 ? 233 GLU B CD 1 ATOM 5161 O OE1 . GLU B 1 233 ? 20.056 -36.611 25.238 1.00 32.19 ? 233 GLU B OE1 1 ATOM 5162 O OE2 . GLU B 1 233 ? 20.978 -38.083 23.906 1.00 27.81 ? 233 GLU B OE2 1 ATOM 5163 N N . VAL B 1 234 ? 19.017 -31.416 23.081 1.00 25.13 ? 234 VAL B N 1 ATOM 5164 C CA . VAL B 1 234 ? 18.048 -30.362 23.009 1.00 24.92 ? 234 VAL B CA 1 ATOM 5165 C C . VAL B 1 234 ? 18.233 -29.654 21.680 1.00 25.54 ? 234 VAL B C 1 ATOM 5166 O O . VAL B 1 234 ? 17.241 -29.400 20.990 1.00 25.23 ? 234 VAL B O 1 ATOM 5167 C CB . VAL B 1 234 ? 18.148 -29.349 24.177 1.00 25.32 ? 234 VAL B CB 1 ATOM 5168 C CG1 . VAL B 1 234 ? 17.188 -28.219 23.937 1.00 24.82 ? 234 VAL B CG1 1 ATOM 5169 C CG2 . VAL B 1 234 ? 17.856 -30.022 25.535 1.00 22.80 ? 234 VAL B CG2 1 ATOM 5170 N N . THR B 1 235 ? 19.479 -29.361 21.276 1.00 25.11 ? 235 THR B N 1 ATOM 5171 C CA . THR B 1 235 ? 19.611 -28.716 19.976 1.00 24.68 ? 235 THR B CA 1 ATOM 5172 C C . THR B 1 235 ? 19.095 -29.598 18.830 1.00 24.65 ? 235 THR B C 1 ATOM 5173 O O . THR B 1 235 ? 18.613 -29.068 17.833 1.00 24.52 ? 235 THR B O 1 ATOM 5174 C CB . THR B 1 235 ? 20.997 -28.156 19.671 1.00 24.45 ? 235 THR B CB 1 ATOM 5175 O OG1 . THR B 1 235 ? 21.885 -29.219 19.360 1.00 24.54 ? 235 THR B OG1 1 ATOM 5176 C CG2 . THR B 1 235 ? 21.503 -27.354 20.846 1.00 25.65 ? 235 THR B CG2 1 ATOM 5177 N N . TYR B 1 236 ? 19.131 -30.919 18.995 1.00 24.20 ? 236 TYR B N 1 ATOM 5178 C CA . TYR B 1 236 ? 18.545 -31.816 17.988 1.00 24.53 ? 236 TYR B CA 1 ATOM 5179 C C . TYR B 1 236 ? 17.040 -31.597 17.815 1.00 24.71 ? 236 TYR B C 1 ATOM 5180 O O . TYR B 1 236 ? 16.579 -31.443 16.684 1.00 24.97 ? 236 TYR B O 1 ATOM 5181 C CB . TYR B 1 236 ? 18.860 -33.303 18.251 1.00 24.71 ? 236 TYR B CB 1 ATOM 5182 C CG . TYR B 1 236 ? 20.339 -33.687 18.207 1.00 27.19 ? 236 TYR B CG 1 ATOM 5183 C CD1 . TYR B 1 236 ? 21.301 -32.842 17.629 1.00 27.49 ? 236 TYR B CD1 1 ATOM 5184 C CD2 . TYR B 1 236 ? 20.766 -34.928 18.703 1.00 29.25 ? 236 TYR B CD2 1 ATOM 5185 C CE1 . TYR B 1 236 ? 22.656 -33.197 17.594 1.00 30.76 ? 236 TYR B CE1 1 ATOM 5186 C CE2 . TYR B 1 236 ? 22.115 -35.315 18.658 1.00 30.08 ? 236 TYR B CE2 1 ATOM 5187 C CZ . TYR B 1 236 ? 23.060 -34.440 18.107 1.00 32.46 ? 236 TYR B CZ 1 ATOM 5188 O OH . TYR B 1 236 ? 24.399 -34.809 18.062 1.00 34.71 ? 236 TYR B OH 1 ATOM 5189 N N . LEU B 1 237 ? 16.283 -31.563 18.910 1.00 24.25 ? 237 LEU B N 1 ATOM 5190 C CA . LEU B 1 237 ? 14.840 -31.256 18.837 1.00 24.38 ? 237 LEU B CA 1 ATOM 5191 C C . LEU B 1 237 ? 14.597 -29.882 18.218 1.00 25.16 ? 237 LEU B C 1 ATOM 5192 O O . LEU B 1 237 ? 13.627 -29.682 17.501 1.00 25.57 ? 237 LEU B O 1 ATOM 5193 C CB . LEU B 1 237 ? 14.184 -31.320 20.212 1.00 23.61 ? 237 LEU B CB 1 ATOM 5194 C CG . LEU B 1 237 ? 14.200 -32.684 20.910 1.00 23.62 ? 237 LEU B CG 1 ATOM 5195 C CD1 . LEU B 1 237 ? 13.687 -32.490 22.311 1.00 22.87 ? 237 LEU B CD1 1 ATOM 5196 C CD2 . LEU B 1 237 ? 13.380 -33.766 20.172 1.00 17.93 ? 237 LEU B CD2 1 ATOM 5197 N N . MET B 1 238 ? 15.492 -28.937 18.483 1.00 25.26 ? 238 MET B N 1 ATOM 5198 C CA . MET B 1 238 ? 15.417 -27.662 17.800 1.00 25.72 ? 238 MET B CA 1 ATOM 5199 C C . MET B 1 238 ? 15.659 -27.821 16.279 1.00 26.15 ? 238 MET B C 1 ATOM 5200 O O . MET B 1 238 ? 14.837 -27.355 15.483 1.00 26.33 ? 238 MET B O 1 ATOM 5201 C CB . MET B 1 238 ? 16.317 -26.632 18.482 1.00 25.62 ? 238 MET B CB 1 ATOM 5202 C CG . MET B 1 238 ? 15.810 -26.299 19.918 1.00 25.04 ? 238 MET B CG 1 ATOM 5203 S SD . MET B 1 238 ? 16.745 -24.959 20.682 1.00 27.17 ? 238 MET B SD 1 ATOM 5204 C CE . MET B 1 238 ? 15.801 -23.530 20.175 1.00 22.36 ? 238 MET B CE 1 ATOM 5205 N N . ASP B 1 239 ? 16.729 -28.536 15.896 1.00 25.94 ? 239 ASP B N 1 ATOM 5206 C CA . ASP B 1 239 ? 17.040 -28.840 14.489 1.00 25.84 ? 239 ASP B CA 1 ATOM 5207 C C . ASP B 1 239 ? 15.792 -29.476 13.808 1.00 26.31 ? 239 ASP B C 1 ATOM 5208 O O . ASP B 1 239 ? 15.446 -29.112 12.690 1.00 25.93 ? 239 ASP B O 1 ATOM 5209 C CB . ASP B 1 239 ? 18.248 -29.814 14.330 1.00 25.28 ? 239 ASP B CB 1 ATOM 5210 C CG . ASP B 1 239 ? 19.635 -29.203 14.675 1.00 24.20 ? 239 ASP B CG 1 ATOM 5211 O OD1 . ASP B 1 239 ? 19.829 -27.989 14.875 1.00 22.42 ? 239 ASP B OD1 1 ATOM 5212 O OD2 . ASP B 1 239 ? 20.588 -29.999 14.757 1.00 25.23 ? 239 ASP B OD2 1 ATOM 5213 N N . MET B 1 240 ? 15.103 -30.393 14.498 1.00 27.18 ? 240 MET B N 1 ATOM 5214 C CA . MET B 1 240 ? 13.882 -31.046 13.954 1.00 27.38 ? 240 MET B CA 1 ATOM 5215 C C . MET B 1 240 ? 12.763 -30.116 13.515 1.00 27.94 ? 240 MET B C 1 ATOM 5216 O O . MET B 1 240 ? 11.980 -30.488 12.646 1.00 28.63 ? 240 MET B O 1 ATOM 5217 C CB . MET B 1 240 ? 13.313 -32.069 14.912 1.00 27.43 ? 240 MET B CB 1 ATOM 5218 C CG . MET B 1 240 ? 14.059 -33.386 14.873 1.00 28.78 ? 240 MET B CG 1 ATOM 5219 S SD . MET B 1 240 ? 14.193 -34.109 13.216 1.00 32.09 ? 240 MET B SD 1 ATOM 5220 C CE . MET B 1 240 ? 12.468 -34.560 13.000 1.00 28.62 ? 240 MET B CE 1 ATOM 5221 N N . CYS B 1 241 ? 12.701 -28.908 14.084 1.00 28.39 ? 241 CYS B N 1 ATOM 5222 C CA . CYS B 1 241 ? 11.671 -27.926 13.742 1.00 28.78 ? 241 CYS B CA 1 ATOM 5223 C C . CYS B 1 241 ? 11.864 -27.357 12.328 1.00 28.56 ? 241 CYS B C 1 ATOM 5224 O O . CYS B 1 241 ? 10.911 -27.004 11.652 1.00 29.21 ? 241 CYS B O 1 ATOM 5225 C CB . CYS B 1 241 ? 11.673 -26.833 14.791 1.00 28.63 ? 241 CYS B CB 1 ATOM 5226 S SG . CYS B 1 241 ? 11.040 -25.247 14.261 1.00 32.47 ? 241 CYS B SG 1 ATOM 5227 N N . SER B 1 242 ? 13.106 -27.280 11.869 1.00 28.17 ? 242 SER B N 1 ATOM 5228 C CA . SER B 1 242 ? 13.373 -26.904 10.499 1.00 26.82 ? 242 SER B CA 1 ATOM 5229 C C . SER B 1 242 ? 13.052 -28.105 9.595 1.00 26.94 ? 242 SER B C 1 ATOM 5230 O O . SER B 1 242 ? 12.256 -27.999 8.659 1.00 26.49 ? 242 SER B O 1 ATOM 5231 C CB . SER B 1 242 ? 14.837 -26.487 10.340 1.00 26.82 ? 242 SER B CB 1 ATOM 5232 O OG . SER B 1 242 ? 15.107 -25.971 9.049 1.00 25.22 ? 242 SER B OG 1 ATOM 5233 N N . PHE B 1 243 ? 13.645 -29.245 9.897 1.00 26.29 ? 243 PHE B N 1 ATOM 5234 C CA . PHE B 1 243 ? 13.532 -30.397 9.031 1.00 27.00 ? 243 PHE B CA 1 ATOM 5235 C C . PHE B 1 243 ? 12.140 -30.977 8.924 1.00 27.70 ? 243 PHE B C 1 ATOM 5236 O O . PHE B 1 243 ? 11.732 -31.379 7.841 1.00 28.24 ? 243 PHE B O 1 ATOM 5237 C CB . PHE B 1 243 ? 14.488 -31.475 9.489 1.00 27.13 ? 243 PHE B CB 1 ATOM 5238 C CG . PHE B 1 243 ? 15.918 -31.173 9.184 1.00 27.02 ? 243 PHE B CG 1 ATOM 5239 C CD1 . PHE B 1 243 ? 16.389 -31.245 7.887 1.00 27.14 ? 243 PHE B CD1 1 ATOM 5240 C CD2 . PHE B 1 243 ? 16.797 -30.830 10.196 1.00 26.19 ? 243 PHE B CD2 1 ATOM 5241 C CE1 . PHE B 1 243 ? 17.735 -30.999 7.602 1.00 28.05 ? 243 PHE B CE1 1 ATOM 5242 C CE2 . PHE B 1 243 ? 18.130 -30.575 9.923 1.00 27.51 ? 243 PHE B CE2 1 ATOM 5243 C CZ . PHE B 1 243 ? 18.602 -30.652 8.641 1.00 27.39 ? 243 PHE B CZ 1 ATOM 5244 N N . ASP B 1 244 ? 11.405 -31.045 10.034 1.00 28.54 ? 244 ASP B N 1 ATOM 5245 C CA . ASP B 1 244 ? 10.029 -31.558 10.007 1.00 29.12 ? 244 ASP B CA 1 ATOM 5246 C C . ASP B 1 244 ? 9.104 -30.595 9.258 1.00 30.02 ? 244 ASP B C 1 ATOM 5247 O O . ASP B 1 244 ? 8.069 -30.993 8.743 1.00 30.30 ? 244 ASP B O 1 ATOM 5248 C CB . ASP B 1 244 ? 9.500 -31.808 11.426 1.00 28.47 ? 244 ASP B CB 1 ATOM 5249 C CG . ASP B 1 244 ? 8.188 -32.604 11.437 1.00 28.39 ? 244 ASP B CG 1 ATOM 5250 O OD1 . ASP B 1 244 ? 8.195 -33.784 11.036 1.00 27.31 ? 244 ASP B OD1 1 ATOM 5251 O OD2 . ASP B 1 244 ? 7.145 -32.049 11.865 1.00 29.32 ? 244 ASP B OD2 1 ATOM 5252 N N . THR B 1 245 ? 9.464 -29.322 9.207 1.00 31.15 ? 245 THR B N 1 ATOM 5253 C CA . THR B 1 245 ? 8.631 -28.389 8.487 1.00 32.90 ? 245 THR B CA 1 ATOM 5254 C C . THR B 1 245 ? 8.846 -28.513 6.972 1.00 33.86 ? 245 THR B C 1 ATOM 5255 O O . THR B 1 245 ? 7.921 -28.825 6.218 1.00 34.07 ? 245 THR B O 1 ATOM 5256 C CB . THR B 1 245 ? 8.884 -26.959 8.943 1.00 32.36 ? 245 THR B CB 1 ATOM 5257 O OG1 . THR B 1 245 ? 8.570 -26.880 10.319 1.00 34.05 ? 245 THR B OG1 1 ATOM 5258 C CG2 . THR B 1 245 ? 7.980 -25.981 8.205 1.00 32.27 ? 245 THR B CG2 1 ATOM 5259 N N . ILE B 1 246 ? 10.078 -28.290 6.549 1.00 35.09 ? 246 ILE B N 1 ATOM 5260 C CA . ILE B 1 246 ? 10.369 -28.076 5.141 1.00 36.38 ? 246 ILE B CA 1 ATOM 5261 C C . ILE B 1 246 ? 10.731 -29.344 4.366 1.00 37.59 ? 246 ILE B C 1 ATOM 5262 O O . ILE B 1 246 ? 11.229 -29.272 3.245 1.00 38.55 ? 246 ILE B O 1 ATOM 5263 C CB . ILE B 1 246 ? 11.405 -26.932 4.967 1.00 35.90 ? 246 ILE B CB 1 ATOM 5264 C CG1 . ILE B 1 246 ? 12.808 -27.365 5.381 1.00 34.49 ? 246 ILE B CG1 1 ATOM 5265 C CG2 . ILE B 1 246 ? 10.978 -25.721 5.774 1.00 34.20 ? 246 ILE B CG2 1 ATOM 5266 C CD1 . ILE B 1 246 ? 13.827 -26.253 5.178 1.00 32.37 ? 246 ILE B CD1 1 ATOM 5267 N N . SER B 1 247 ? 10.459 -30.498 4.971 1.00 39.44 ? 247 SER B N 1 ATOM 5268 C CA . SER B 1 247 ? 10.745 -31.802 4.370 1.00 41.16 ? 247 SER B CA 1 ATOM 5269 C C . SER B 1 247 ? 9.494 -32.447 3.856 1.00 42.14 ? 247 SER B C 1 ATOM 5270 O O . SER B 1 247 ? 9.569 -33.374 3.065 1.00 43.22 ? 247 SER B O 1 ATOM 5271 C CB . SER B 1 247 ? 11.371 -32.767 5.379 1.00 41.24 ? 247 SER B CB 1 ATOM 5272 O OG . SER B 1 247 ? 12.678 -32.354 5.748 1.00 42.37 ? 247 SER B OG 1 ATOM 5273 N N . THR B 1 248 ? 8.341 -31.979 4.294 1.00 43.45 ? 248 THR B N 1 ATOM 5274 C CA . THR B 1 248 ? 7.099 -32.611 3.858 1.00 45.01 ? 248 THR B CA 1 ATOM 5275 C C . THR B 1 248 ? 6.191 -31.745 2.996 1.00 44.93 ? 248 THR B C 1 ATOM 5276 O O . THR B 1 248 ? 6.491 -30.571 2.715 1.00 44.80 ? 248 THR B O 1 ATOM 5277 C CB . THR B 1 248 ? 6.250 -33.152 5.055 1.00 45.60 ? 248 THR B CB 1 ATOM 5278 O OG1 . THR B 1 248 ? 4.879 -33.263 4.640 1.00 47.24 ? 248 THR B OG1 1 ATOM 5279 C CG2 . THR B 1 248 ? 6.331 -32.194 6.266 1.00 45.90 ? 248 THR B CG2 1 ATOM 5280 N N . SER B 1 249 ? 5.089 -32.396 2.600 1.00 45.13 ? 249 SER B N 1 ATOM 5281 C CA . SER B 1 249 ? 3.925 -31.836 1.934 1.00 45.17 ? 249 SER B CA 1 ATOM 5282 C C . SER B 1 249 ? 3.630 -30.477 2.508 1.00 44.34 ? 249 SER B C 1 ATOM 5283 O O . SER B 1 249 ? 3.483 -29.505 1.761 1.00 44.38 ? 249 SER B O 1 ATOM 5284 C CB . SER B 1 249 ? 2.710 -32.782 2.148 1.00 45.73 ? 249 SER B CB 1 ATOM 5285 O OG . SER B 1 249 ? 1.493 -32.264 1.607 1.00 46.80 ? 249 SER B OG 1 ATOM 5286 N N . THR B 1 250 ? 3.595 -30.416 3.835 1.00 43.26 ? 250 THR B N 1 ATOM 5287 C CA . THR B 1 250 ? 3.062 -29.258 4.533 1.00 42.56 ? 250 THR B CA 1 ATOM 5288 C C . THR B 1 250 ? 3.967 -28.032 4.587 1.00 41.90 ? 250 THR B C 1 ATOM 5289 O O . THR B 1 250 ? 3.670 -27.108 5.350 1.00 41.30 ? 250 THR B O 1 ATOM 5290 C CB . THR B 1 250 ? 2.533 -29.597 5.980 1.00 42.98 ? 250 THR B CB 1 ATOM 5291 O OG1 . THR B 1 250 ? 3.275 -30.690 6.553 1.00 42.63 ? 250 THR B OG1 1 ATOM 5292 C CG2 . THR B 1 250 ? 1.037 -29.967 5.914 1.00 44.17 ? 250 THR B CG2 1 ATOM 5293 N N . VAL B 1 251 ? 5.039 -27.993 3.783 1.00 41.45 ? 251 VAL B N 1 ATOM 5294 C CA . VAL B 1 251 ? 5.970 -26.853 3.845 1.00 41.50 ? 251 VAL B CA 1 ATOM 5295 C C . VAL B 1 251 ? 5.253 -25.533 3.975 1.00 41.53 ? 251 VAL B C 1 ATOM 5296 O O . VAL B 1 251 ? 5.597 -24.710 4.832 1.00 40.62 ? 251 VAL B O 1 ATOM 5297 C CB . VAL B 1 251 ? 6.862 -26.619 2.614 1.00 41.42 ? 251 VAL B CB 1 ATOM 5298 C CG1 . VAL B 1 251 ? 8.300 -26.541 2.987 1.00 41.97 ? 251 VAL B CG1 1 ATOM 5299 C CG2 . VAL B 1 251 ? 6.547 -27.484 1.453 1.00 41.98 ? 251 VAL B CG2 1 ATOM 5300 N N . ASP B 1 252 ? 4.276 -25.336 3.088 1.00 42.16 ? 252 ASP B N 1 ATOM 5301 C CA . ASP B 1 252 ? 3.547 -24.069 2.962 1.00 42.48 ? 252 ASP B CA 1 ATOM 5302 C C . ASP B 1 252 ? 2.331 -23.912 3.901 1.00 42.02 ? 252 ASP B C 1 ATOM 5303 O O . ASP B 1 252 ? 1.886 -22.803 4.146 1.00 41.93 ? 252 ASP B O 1 ATOM 5304 C CB . ASP B 1 252 ? 3.142 -23.851 1.494 1.00 42.45 ? 252 ASP B CB 1 ATOM 5305 C CG . ASP B 1 252 ? 4.322 -23.404 0.616 1.00 44.92 ? 252 ASP B CG 1 ATOM 5306 O OD1 . ASP B 1 252 ? 4.408 -22.202 0.314 1.00 47.65 ? 252 ASP B OD1 1 ATOM 5307 O OD2 . ASP B 1 252 ? 5.182 -24.221 0.229 1.00 46.77 ? 252 ASP B OD2 1 ATOM 5308 N N . THR B 1 253 ? 1.805 -25.009 4.430 1.00 42.42 ? 253 THR B N 1 ATOM 5309 C CA . THR B 1 253 ? 0.548 -24.957 5.206 1.00 43.11 ? 253 THR B CA 1 ATOM 5310 C C . THR B 1 253 ? 0.699 -24.999 6.741 1.00 43.36 ? 253 THR B C 1 ATOM 5311 O O . THR B 1 253 ? -0.009 -24.268 7.453 1.00 43.53 ? 253 THR B O 1 ATOM 5312 C CB . THR B 1 253 ? -0.465 -26.040 4.730 1.00 43.31 ? 253 THR B CB 1 ATOM 5313 O OG1 . THR B 1 253 ? 0.226 -27.273 4.450 1.00 43.72 ? 253 THR B OG1 1 ATOM 5314 C CG2 . THR B 1 253 ? -1.196 -25.575 3.461 1.00 43.48 ? 253 THR B CG2 1 ATOM 5315 N N . LYS B 1 254 ? 1.614 -25.839 7.249 1.00 43.29 ? 254 LYS B N 1 ATOM 5316 C CA . LYS B 1 254 ? 1.819 -25.971 8.702 1.00 42.94 ? 254 LYS B CA 1 ATOM 5317 C C . LYS B 1 254 ? 3.283 -25.857 9.110 1.00 42.41 ? 254 LYS B C 1 ATOM 5318 O O . LYS B 1 254 ? 4.171 -26.459 8.483 1.00 42.17 ? 254 LYS B O 1 ATOM 5319 C CB . LYS B 1 254 ? 1.229 -27.293 9.243 1.00 43.03 ? 254 LYS B CB 1 ATOM 5320 N N . LEU B 1 255 ? 3.512 -25.077 10.170 1.00 41.83 ? 255 LEU B N 1 ATOM 5321 C CA . LEU B 1 255 ? 4.771 -25.106 10.933 1.00 41.37 ? 255 LEU B CA 1 ATOM 5322 C C . LEU B 1 255 ? 4.869 -26.411 11.761 1.00 40.89 ? 255 LEU B C 1 ATOM 5323 O O . LEU B 1 255 ? 3.882 -26.821 12.401 1.00 41.25 ? 255 LEU B O 1 ATOM 5324 C CB . LEU B 1 255 ? 4.844 -23.872 11.844 1.00 41.23 ? 255 LEU B CB 1 ATOM 5325 C CG . LEU B 1 255 ? 6.169 -23.490 12.505 1.00 40.38 ? 255 LEU B CG 1 ATOM 5326 C CD1 . LEU B 1 255 ? 7.286 -23.377 11.460 1.00 39.18 ? 255 LEU B CD1 1 ATOM 5327 C CD2 . LEU B 1 255 ? 6.009 -22.194 13.318 1.00 38.27 ? 255 LEU B CD2 1 ATOM 5328 N N . SER B 1 256 ? 6.030 -27.069 11.732 1.00 39.93 ? 256 SER B N 1 ATOM 5329 C CA . SER B 1 256 ? 6.225 -28.343 12.462 1.00 39.17 ? 256 SER B CA 1 ATOM 5330 C C . SER B 1 256 ? 5.826 -28.266 13.931 1.00 38.51 ? 256 SER B C 1 ATOM 5331 O O . SER B 1 256 ? 5.988 -27.209 14.557 1.00 38.06 ? 256 SER B O 1 ATOM 5332 C CB . SER B 1 256 ? 7.679 -28.814 12.395 1.00 39.17 ? 256 SER B CB 1 ATOM 5333 O OG . SER B 1 256 ? 7.847 -29.941 13.231 1.00 38.45 ? 256 SER B OG 1 ATOM 5334 N N . PRO B 1 257 ? 5.301 -29.386 14.488 1.00 38.23 ? 257 PRO B N 1 ATOM 5335 C CA . PRO B 1 257 ? 4.900 -29.397 15.916 1.00 37.51 ? 257 PRO B CA 1 ATOM 5336 C C . PRO B 1 257 ? 6.107 -29.168 16.873 1.00 36.69 ? 257 PRO B C 1 ATOM 5337 O O . PRO B 1 257 ? 5.957 -28.544 17.942 1.00 36.32 ? 257 PRO B O 1 ATOM 5338 C CB . PRO B 1 257 ? 4.288 -30.791 16.102 1.00 37.78 ? 257 PRO B CB 1 ATOM 5339 C CG . PRO B 1 257 ? 4.068 -31.356 14.721 1.00 37.74 ? 257 PRO B CG 1 ATOM 5340 C CD . PRO B 1 257 ? 5.062 -30.689 13.831 1.00 38.21 ? 257 PRO B CD 1 ATOM 5341 N N . PHE B 1 258 ? 7.289 -29.634 16.449 1.00 35.33 ? 258 PHE B N 1 ATOM 5342 C CA . PHE B 1 258 ? 8.558 -29.402 17.143 1.00 33.85 ? 258 PHE B CA 1 ATOM 5343 C C . PHE B 1 258 ? 8.848 -27.932 17.467 1.00 32.94 ? 258 PHE B C 1 ATOM 5344 O O . PHE B 1 258 ? 9.479 -27.626 18.483 1.00 32.54 ? 258 PHE B O 1 ATOM 5345 C CB . PHE B 1 258 ? 9.706 -29.959 16.311 1.00 34.03 ? 258 PHE B CB 1 ATOM 5346 C CG . PHE B 1 258 ? 9.845 -31.448 16.366 1.00 33.67 ? 258 PHE B CG 1 ATOM 5347 C CD1 . PHE B 1 258 ? 10.258 -32.079 17.538 1.00 34.02 ? 258 PHE B CD1 1 ATOM 5348 C CD2 . PHE B 1 258 ? 9.617 -32.225 15.234 1.00 34.35 ? 258 PHE B CD2 1 ATOM 5349 C CE1 . PHE B 1 258 ? 10.426 -33.482 17.605 1.00 33.01 ? 258 PHE B CE1 1 ATOM 5350 C CE2 . PHE B 1 258 ? 9.775 -33.651 15.275 1.00 34.55 ? 258 PHE B CE2 1 ATOM 5351 C CZ . PHE B 1 258 ? 10.189 -34.273 16.470 1.00 34.01 ? 258 PHE B CZ 1 ATOM 5352 N N . CYS B 1 259 ? 8.385 -27.026 16.621 1.00 32.00 ? 259 CYS B N 1 ATOM 5353 C CA . CYS B 1 259 ? 8.699 -25.601 16.773 1.00 31.89 ? 259 CYS B CA 1 ATOM 5354 C C . CYS B 1 259 ? 8.045 -24.945 17.964 1.00 31.99 ? 259 CYS B C 1 ATOM 5355 O O . CYS B 1 259 ? 8.566 -23.953 18.510 1.00 31.93 ? 259 CYS B O 1 ATOM 5356 C CB . CYS B 1 259 ? 8.330 -24.820 15.512 1.00 31.35 ? 259 CYS B CB 1 ATOM 5357 S SG . CYS B 1 259 ? 9.023 -25.565 14.063 1.00 30.47 ? 259 CYS B SG 1 ATOM 5358 N N . ASP B 1 260 ? 6.899 -25.488 18.351 1.00 32.07 ? 260 ASP B N 1 ATOM 5359 C CA . ASP B 1 260 ? 6.104 -24.917 19.437 1.00 32.74 ? 260 ASP B CA 1 ATOM 5360 C C . ASP B 1 260 ? 6.651 -25.315 20.820 1.00 31.75 ? 260 ASP B C 1 ATOM 5361 O O . ASP B 1 260 ? 6.242 -24.743 21.828 1.00 31.92 ? 260 ASP B O 1 ATOM 5362 C CB . ASP B 1 260 ? 4.619 -25.312 19.283 1.00 33.41 ? 260 ASP B CB 1 ATOM 5363 C CG . ASP B 1 260 ? 3.652 -24.381 20.073 1.00 37.94 ? 260 ASP B CG 1 ATOM 5364 O OD1 . ASP B 1 260 ? 4.053 -23.234 20.468 1.00 40.36 ? 260 ASP B OD1 1 ATOM 5365 O OD2 . ASP B 1 260 ? 2.472 -24.809 20.287 1.00 40.27 ? 260 ASP B OD2 1 ATOM 5366 N N . LEU B 1 261 ? 7.571 -26.286 20.865 1.00 30.53 ? 261 LEU B N 1 ATOM 5367 C CA . LEU B 1 261 ? 8.242 -26.681 22.112 1.00 29.22 ? 261 LEU B CA 1 ATOM 5368 C C . LEU B 1 261 ? 9.279 -25.658 22.559 1.00 28.67 ? 261 LEU B C 1 ATOM 5369 O O . LEU B 1 261 ? 9.824 -25.732 23.652 1.00 29.24 ? 261 LEU B O 1 ATOM 5370 C CB . LEU B 1 261 ? 8.889 -28.057 21.972 1.00 28.47 ? 261 LEU B CB 1 ATOM 5371 C CG . LEU B 1 261 ? 8.023 -29.227 21.466 1.00 28.00 ? 261 LEU B CG 1 ATOM 5372 C CD1 . LEU B 1 261 ? 8.905 -30.412 21.185 1.00 26.03 ? 261 LEU B CD1 1 ATOM 5373 C CD2 . LEU B 1 261 ? 6.893 -29.645 22.430 1.00 25.68 ? 261 LEU B CD2 1 ATOM 5374 N N . PHE B 1 262 ? 9.545 -24.680 21.727 1.00 27.78 ? 262 PHE B N 1 ATOM 5375 C CA . PHE B 1 262 ? 10.507 -23.660 22.084 1.00 27.58 ? 262 PHE B CA 1 ATOM 5376 C C . PHE B 1 262 ? 9.828 -22.297 21.991 1.00 27.91 ? 262 PHE B C 1 ATOM 5377 O O . PHE B 1 262 ? 8.793 -22.175 21.368 1.00 28.40 ? 262 PHE B O 1 ATOM 5378 C CB . PHE B 1 262 ? 11.753 -23.835 21.208 1.00 26.33 ? 262 PHE B CB 1 ATOM 5379 C CG . PHE B 1 262 ? 12.253 -25.253 21.211 1.00 25.16 ? 262 PHE B CG 1 ATOM 5380 C CD1 . PHE B 1 262 ? 12.957 -25.754 22.298 1.00 25.48 ? 262 PHE B CD1 1 ATOM 5381 C CD2 . PHE B 1 262 ? 11.960 -26.114 20.183 1.00 21.33 ? 262 PHE B CD2 1 ATOM 5382 C CE1 . PHE B 1 262 ? 13.384 -27.105 22.345 1.00 23.56 ? 262 PHE B CE1 1 ATOM 5383 C CE2 . PHE B 1 262 ? 12.402 -27.425 20.210 1.00 24.21 ? 262 PHE B CE2 1 ATOM 5384 C CZ . PHE B 1 262 ? 13.118 -27.925 21.310 1.00 23.47 ? 262 PHE B CZ 1 ATOM 5385 N N . THR B 1 263 ? 10.360 -21.287 22.656 1.00 28.32 ? 263 THR B N 1 ATOM 5386 C CA . THR B 1 263 ? 9.766 -19.974 22.577 1.00 28.16 ? 263 THR B CA 1 ATOM 5387 C C . THR B 1 263 ? 10.510 -19.122 21.558 1.00 29.29 ? 263 THR B C 1 ATOM 5388 O O . THR B 1 263 ? 11.667 -19.432 21.169 1.00 28.40 ? 263 THR B O 1 ATOM 5389 C CB . THR B 1 263 ? 9.889 -19.228 23.886 1.00 28.05 ? 263 THR B CB 1 ATOM 5390 O OG1 . THR B 1 263 ? 11.275 -19.028 24.170 1.00 25.96 ? 263 THR B OG1 1 ATOM 5391 C CG2 . THR B 1 263 ? 9.263 -19.999 25.004 1.00 29.04 ? 263 THR B CG2 1 ATOM 5392 N N . HIS B 1 264 ? 9.870 -18.011 21.179 1.00 30.01 ? 264 HIS B N 1 ATOM 5393 C CA . HIS B 1 264 ? 10.472 -17.063 20.266 1.00 31.22 ? 264 HIS B CA 1 ATOM 5394 C C . HIS B 1 264 ? 11.896 -16.696 20.682 1.00 31.66 ? 264 HIS B C 1 ATOM 5395 O O . HIS B 1 264 ? 12.821 -16.722 19.851 1.00 32.29 ? 264 HIS B O 1 ATOM 5396 C CB . HIS B 1 264 ? 9.611 -15.803 20.131 1.00 31.55 ? 264 HIS B CB 1 ATOM 5397 C CG . HIS B 1 264 ? 10.143 -14.812 19.135 1.00 33.15 ? 264 HIS B CG 1 ATOM 5398 N ND1 . HIS B 1 264 ? 10.279 -15.104 17.793 1.00 34.05 ? 264 HIS B ND1 1 ATOM 5399 C CD2 . HIS B 1 264 ? 10.554 -13.529 19.285 1.00 33.74 ? 264 HIS B CD2 1 ATOM 5400 C CE1 . HIS B 1 264 ? 10.754 -14.044 17.160 1.00 33.05 ? 264 HIS B CE1 1 ATOM 5401 N NE2 . HIS B 1 264 ? 10.921 -13.072 18.041 1.00 33.47 ? 264 HIS B NE2 1 ATOM 5402 N N . ASP B 1 265 ? 12.063 -16.358 21.963 1.00 31.43 ? 265 ASP B N 1 ATOM 5403 C CA . ASP B 1 265 ? 13.348 -15.896 22.488 1.00 31.32 ? 265 ASP B CA 1 ATOM 5404 C C . ASP B 1 265 ? 14.371 -17.030 22.438 1.00 30.44 ? 265 ASP B C 1 ATOM 5405 O O . ASP B 1 265 ? 15.546 -16.814 22.124 1.00 29.70 ? 265 ASP B O 1 ATOM 5406 C CB . ASP B 1 265 ? 13.204 -15.302 23.917 1.00 32.29 ? 265 ASP B CB 1 ATOM 5407 N N . GLU B 1 266 ? 13.902 -18.236 22.746 1.00 29.07 ? 266 GLU B N 1 ATOM 5408 C CA . GLU B 1 266 ? 14.665 -19.435 22.504 1.00 28.06 ? 266 GLU B CA 1 ATOM 5409 C C . GLU B 1 266 ? 15.032 -19.610 21.044 1.00 27.59 ? 266 GLU B C 1 ATOM 5410 O O . GLU B 1 266 ? 16.185 -19.981 20.760 1.00 27.67 ? 266 GLU B O 1 ATOM 5411 C CB . GLU B 1 266 ? 13.946 -20.647 23.022 1.00 28.00 ? 266 GLU B CB 1 ATOM 5412 C CG . GLU B 1 266 ? 14.104 -20.760 24.513 1.00 29.66 ? 266 GLU B CG 1 ATOM 5413 C CD . GLU B 1 266 ? 13.062 -21.620 25.182 1.00 31.48 ? 266 GLU B CD 1 ATOM 5414 O OE1 . GLU B 1 266 ? 12.563 -22.587 24.576 1.00 29.19 ? 266 GLU B OE1 1 ATOM 5415 O OE2 . GLU B 1 266 ? 12.750 -21.315 26.345 1.00 34.43 ? 266 GLU B OE2 1 ATOM 5416 N N . TRP B 1 267 ? 14.103 -19.320 20.117 1.00 25.91 ? 267 TRP B N 1 ATOM 5417 C CA . TRP B 1 267 ? 14.510 -19.241 18.696 1.00 24.53 ? 267 TRP B CA 1 ATOM 5418 C C . TRP B 1 267 ? 15.613 -18.215 18.373 1.00 24.79 ? 267 TRP B C 1 ATOM 5419 O O . TRP B 1 267 ? 16.533 -18.522 17.621 1.00 24.59 ? 267 TRP B O 1 ATOM 5420 C CB . TRP B 1 267 ? 13.321 -19.138 17.744 1.00 23.81 ? 267 TRP B CB 1 ATOM 5421 C CG . TRP B 1 267 ? 12.597 -20.458 17.699 1.00 21.37 ? 267 TRP B CG 1 ATOM 5422 C CD1 . TRP B 1 267 ? 11.313 -20.728 18.131 1.00 18.76 ? 267 TRP B CD1 1 ATOM 5423 C CD2 . TRP B 1 267 ? 13.149 -21.703 17.271 1.00 17.44 ? 267 TRP B CD2 1 ATOM 5424 N NE1 . TRP B 1 267 ? 11.032 -22.059 17.945 1.00 17.73 ? 267 TRP B NE1 1 ATOM 5425 C CE2 . TRP B 1 267 ? 12.150 -22.682 17.438 1.00 17.88 ? 267 TRP B CE2 1 ATOM 5426 C CE3 . TRP B 1 267 ? 14.397 -22.082 16.745 1.00 19.08 ? 267 TRP B CE3 1 ATOM 5427 C CZ2 . TRP B 1 267 ? 12.353 -24.022 17.088 1.00 17.95 ? 267 TRP B CZ2 1 ATOM 5428 C CZ3 . TRP B 1 267 ? 14.609 -23.420 16.384 1.00 18.49 ? 267 TRP B CZ3 1 ATOM 5429 C CH2 . TRP B 1 267 ? 13.597 -24.376 16.569 1.00 18.74 ? 267 TRP B CH2 1 ATOM 5430 N N . ILE B 1 268 ? 15.532 -17.020 18.949 1.00 24.54 ? 268 ILE B N 1 ATOM 5431 C CA . ILE B 1 268 ? 16.553 -15.997 18.741 1.00 24.81 ? 268 ILE B CA 1 ATOM 5432 C C . ILE B 1 268 ? 17.977 -16.503 19.075 1.00 25.23 ? 268 ILE B C 1 ATOM 5433 O O . ILE B 1 268 ? 18.942 -16.288 18.301 1.00 24.50 ? 268 ILE B O 1 ATOM 5434 C CB . ILE B 1 268 ? 16.239 -14.726 19.561 1.00 24.95 ? 268 ILE B CB 1 ATOM 5435 C CG1 . ILE B 1 268 ? 15.058 -13.989 18.926 1.00 25.65 ? 268 ILE B CG1 1 ATOM 5436 C CG2 . ILE B 1 268 ? 17.430 -13.793 19.621 1.00 24.81 ? 268 ILE B CG2 1 ATOM 5437 C CD1 . ILE B 1 268 ? 14.590 -12.812 19.716 1.00 27.67 ? 268 ILE B CD1 1 ATOM 5438 N N . ASN B 1 269 ? 18.096 -17.162 20.230 1.00 24.04 ? 269 ASN B N 1 ATOM 5439 C CA . ASN B 1 269 ? 19.343 -17.710 20.655 1.00 23.15 ? 269 ASN B CA 1 ATOM 5440 C C . ASN B 1 269 ? 19.727 -18.757 19.645 1.00 22.92 ? 269 ASN B C 1 ATOM 5441 O O . ASN B 1 269 ? 20.840 -18.743 19.131 1.00 23.36 ? 269 ASN B O 1 ATOM 5442 C CB . ASN B 1 269 ? 19.239 -18.303 22.063 1.00 23.01 ? 269 ASN B CB 1 ATOM 5443 C CG . ASN B 1 269 ? 19.228 -17.242 23.148 1.00 24.95 ? 269 ASN B CG 1 ATOM 5444 O OD1 . ASN B 1 269 ? 20.185 -16.489 23.305 1.00 27.48 ? 269 ASN B OD1 1 ATOM 5445 N ND2 . ASN B 1 269 ? 18.153 -17.199 23.923 1.00 26.81 ? 269 ASN B ND2 1 ATOM 5446 N N . TYR B 1 270 ? 18.811 -19.661 19.326 1.00 22.20 ? 270 TYR B N 1 ATOM 5447 C CA . TYR B 1 270 ? 19.138 -20.650 18.308 1.00 21.50 ? 270 TYR B CA 1 ATOM 5448 C C . TYR B 1 270 ? 19.763 -20.000 17.052 1.00 20.90 ? 270 TYR B C 1 ATOM 5449 O O . TYR B 1 270 ? 20.834 -20.410 16.589 1.00 19.98 ? 270 TYR B O 1 ATOM 5450 C CB . TYR B 1 270 ? 17.919 -21.430 17.924 1.00 20.92 ? 270 TYR B CB 1 ATOM 5451 C CG . TYR B 1 270 ? 18.205 -22.572 16.988 1.00 22.48 ? 270 TYR B CG 1 ATOM 5452 C CD1 . TYR B 1 270 ? 18.648 -23.803 17.468 1.00 21.01 ? 270 TYR B CD1 1 ATOM 5453 C CD2 . TYR B 1 270 ? 18.001 -22.426 15.613 1.00 22.19 ? 270 TYR B CD2 1 ATOM 5454 C CE1 . TYR B 1 270 ? 18.885 -24.861 16.601 1.00 20.63 ? 270 TYR B CE1 1 ATOM 5455 C CE2 . TYR B 1 270 ? 18.239 -23.460 14.747 1.00 22.20 ? 270 TYR B CE2 1 ATOM 5456 C CZ . TYR B 1 270 ? 18.673 -24.689 15.238 1.00 23.18 ? 270 TYR B CZ 1 ATOM 5457 O OH . TYR B 1 270 ? 18.874 -25.731 14.340 1.00 22.09 ? 270 TYR B OH 1 ATOM 5458 N N . ASP B 1 271 ? 19.098 -18.985 16.521 1.00 19.99 ? 271 ASP B N 1 ATOM 5459 C CA . ASP B 1 271 ? 19.589 -18.340 15.324 1.00 20.09 ? 271 ASP B CA 1 ATOM 5460 C C . ASP B 1 271 ? 21.014 -17.864 15.542 1.00 19.90 ? 271 ASP B C 1 ATOM 5461 O O . ASP B 1 271 ? 21.898 -18.140 14.730 1.00 20.56 ? 271 ASP B O 1 ATOM 5462 C CB . ASP B 1 271 ? 18.681 -17.187 14.926 1.00 20.18 ? 271 ASP B CB 1 ATOM 5463 C CG . ASP B 1 271 ? 19.049 -16.583 13.562 1.00 20.47 ? 271 ASP B CG 1 ATOM 5464 O OD1 . ASP B 1 271 ? 18.943 -17.294 12.536 1.00 15.63 ? 271 ASP B OD1 1 ATOM 5465 O OD2 . ASP B 1 271 ? 19.406 -15.377 13.531 1.00 20.76 ? 271 ASP B OD2 1 ATOM 5466 N N . TYR B 1 272 ? 21.230 -17.194 16.667 1.00 18.95 ? 272 TYR B N 1 ATOM 5467 C CA . TYR B 1 272 ? 22.488 -16.565 16.962 1.00 18.36 ? 272 TYR B CA 1 ATOM 5468 C C . TYR B 1 272 ? 23.609 -17.561 17.115 1.00 18.31 ? 272 TYR B C 1 ATOM 5469 O O . TYR B 1 272 ? 24.715 -17.345 16.611 1.00 17.47 ? 272 TYR B O 1 ATOM 5470 C CB . TYR B 1 272 ? 22.368 -15.675 18.192 1.00 18.86 ? 272 TYR B CB 1 ATOM 5471 C CG . TYR B 1 272 ? 23.593 -14.832 18.407 1.00 19.41 ? 272 TYR B CG 1 ATOM 5472 C CD1 . TYR B 1 272 ? 23.858 -13.737 17.601 1.00 20.04 ? 272 TYR B CD1 1 ATOM 5473 C CD2 . TYR B 1 272 ? 24.488 -15.148 19.407 1.00 19.20 ? 272 TYR B CD2 1 ATOM 5474 C CE1 . TYR B 1 272 ? 25.005 -12.989 17.793 1.00 22.37 ? 272 TYR B CE1 1 ATOM 5475 C CE2 . TYR B 1 272 ? 25.612 -14.396 19.620 1.00 21.11 ? 272 TYR B CE2 1 ATOM 5476 C CZ . TYR B 1 272 ? 25.870 -13.316 18.820 1.00 21.34 ? 272 TYR B CZ 1 ATOM 5477 O OH . TYR B 1 272 ? 27.012 -12.591 19.038 1.00 23.48 ? 272 TYR B OH 1 ATOM 5478 N N . LEU B 1 273 ? 23.308 -18.666 17.805 1.00 18.27 ? 273 LEU B N 1 ATOM 5479 C CA . LEU B 1 273 ? 24.183 -19.820 17.817 1.00 18.21 ? 273 LEU B CA 1 ATOM 5480 C C . LEU B 1 273 ? 24.661 -20.145 16.418 1.00 18.39 ? 273 LEU B C 1 ATOM 5481 O O . LEU B 1 273 ? 25.875 -20.234 16.186 1.00 19.43 ? 273 LEU B O 1 ATOM 5482 C CB . LEU B 1 273 ? 23.518 -21.044 18.397 1.00 17.38 ? 273 LEU B CB 1 ATOM 5483 C CG . LEU B 1 273 ? 24.373 -22.309 18.244 1.00 19.12 ? 273 LEU B CG 1 ATOM 5484 C CD1 . LEU B 1 273 ? 25.535 -22.459 19.265 1.00 20.55 ? 273 LEU B CD1 1 ATOM 5485 C CD2 . LEU B 1 273 ? 23.492 -23.499 18.341 1.00 21.93 ? 273 LEU B CD2 1 ATOM 5486 N N . GLN B 1 274 ? 23.727 -20.347 15.486 1.00 18.17 ? 274 GLN B N 1 ATOM 5487 C CA . GLN B 1 274 ? 24.109 -20.657 14.095 1.00 17.32 ? 274 GLN B CA 1 ATOM 5488 C C . GLN B 1 274 ? 25.005 -19.544 13.512 1.00 17.03 ? 274 GLN B C 1 ATOM 5489 O O . GLN B 1 274 ? 25.989 -19.838 12.828 1.00 17.65 ? 274 GLN B O 1 ATOM 5490 C CB . GLN B 1 274 ? 22.898 -20.898 13.190 1.00 17.55 ? 274 GLN B CB 1 ATOM 5491 C CG . GLN B 1 274 ? 21.796 -21.858 13.710 1.00 16.47 ? 274 GLN B CG 1 ATOM 5492 C CD . GLN B 1 274 ? 22.308 -23.192 14.217 1.00 22.67 ? 274 GLN B CD 1 ATOM 5493 O OE1 . GLN B 1 274 ? 23.317 -23.773 13.715 1.00 24.18 ? 274 GLN B OE1 1 ATOM 5494 N NE2 . GLN B 1 274 ? 21.614 -23.709 15.228 1.00 23.87 ? 274 GLN B NE2 1 ATOM 5495 N N . SER B 1 275 ? 24.709 -18.276 13.788 1.00 15.50 ? 275 SER B N 1 ATOM 5496 C CA . SER B 1 275 ? 25.609 -17.253 13.302 1.00 15.50 ? 275 SER B CA 1 ATOM 5497 C C . SER B 1 275 ? 27.032 -17.474 13.820 1.00 15.94 ? 275 SER B C 1 ATOM 5498 O O . SER B 1 275 ? 27.993 -17.304 13.074 1.00 14.39 ? 275 SER B O 1 ATOM 5499 C CB . SER B 1 275 ? 25.080 -15.841 13.596 1.00 15.45 ? 275 SER B CB 1 ATOM 5500 O OG . SER B 1 275 ? 23.811 -15.653 12.986 1.00 15.95 ? 275 SER B OG 1 ATOM 5501 N N . LEU B 1 276 ? 27.156 -17.858 15.109 1.00 17.06 ? 276 LEU B N 1 ATOM 5502 C CA . LEU B 1 276 ? 28.479 -18.137 15.770 1.00 17.05 ? 276 LEU B CA 1 ATOM 5503 C C . LEU B 1 276 ? 29.237 -19.263 15.147 1.00 16.84 ? 276 LEU B C 1 ATOM 5504 O O . LEU B 1 276 ? 30.431 -19.093 14.826 1.00 16.75 ? 276 LEU B O 1 ATOM 5505 C CB . LEU B 1 276 ? 28.354 -18.418 17.277 1.00 17.35 ? 276 LEU B CB 1 ATOM 5506 C CG . LEU B 1 276 ? 28.006 -17.206 18.152 1.00 18.59 ? 276 LEU B CG 1 ATOM 5507 C CD1 . LEU B 1 276 ? 27.546 -17.671 19.521 1.00 15.46 ? 276 LEU B CD1 1 ATOM 5508 C CD2 . LEU B 1 276 ? 29.204 -16.268 18.230 1.00 20.15 ? 276 LEU B CD2 1 ATOM 5509 N N . LYS B 1 277 ? 28.566 -20.405 14.992 1.00 16.29 ? 277 LYS B N 1 ATOM 5510 C CA . LYS B 1 277 ? 29.139 -21.529 14.274 1.00 16.67 ? 277 LYS B CA 1 ATOM 5511 C C . LYS B 1 277 ? 29.777 -21.049 12.933 1.00 17.03 ? 277 LYS B C 1 ATOM 5512 O O . LYS B 1 277 ? 30.994 -21.350 12.622 1.00 16.33 ? 277 LYS B O 1 ATOM 5513 C CB . LYS B 1 277 ? 28.092 -22.595 13.983 1.00 17.11 ? 277 LYS B CB 1 ATOM 5514 C CG . LYS B 1 277 ? 27.421 -23.372 15.170 1.00 18.51 ? 277 LYS B CG 1 ATOM 5515 C CD . LYS B 1 277 ? 27.055 -24.831 14.637 1.00 21.06 ? 277 LYS B CD 1 ATOM 5516 C CE . LYS B 1 277 ? 25.820 -25.497 15.341 1.00 26.40 ? 277 LYS B CE 1 ATOM 5517 N NZ . LYS B 1 277 ? 25.000 -26.553 14.537 1.00 24.76 ? 277 LYS B NZ 1 ATOM 5518 N N . LYS B 1 278 ? 28.985 -20.303 12.138 1.00 16.55 ? 278 LYS B N 1 ATOM 5519 C CA . LYS B 1 278 ? 29.487 -19.835 10.838 1.00 16.39 ? 278 LYS B CA 1 ATOM 5520 C C . LYS B 1 278 ? 30.621 -18.812 10.977 1.00 17.15 ? 278 LYS B C 1 ATOM 5521 O O . LYS B 1 278 ? 31.721 -19.004 10.383 1.00 17.04 ? 278 LYS B O 1 ATOM 5522 C CB . LYS B 1 278 ? 28.369 -19.384 9.892 1.00 16.31 ? 278 LYS B CB 1 ATOM 5523 C CG . LYS B 1 278 ? 27.382 -20.507 9.515 1.00 16.50 ? 278 LYS B CG 1 ATOM 5524 C CD . LYS B 1 278 ? 28.016 -21.870 9.213 1.00 14.99 ? 278 LYS B CD 1 ATOM 5525 C CE . LYS B 1 278 ? 26.972 -22.869 8.691 1.00 15.44 ? 278 LYS B CE 1 ATOM 5526 N NZ . LYS B 1 278 ? 27.598 -24.184 8.316 1.00 13.58 ? 278 LYS B NZ 1 ATOM 5527 N N . TYR B 1 279 ? 30.394 -17.775 11.797 1.00 16.79 ? 279 TYR B N 1 ATOM 5528 C CA . TYR B 1 279 ? 31.409 -16.756 12.024 1.00 17.85 ? 279 TYR B CA 1 ATOM 5529 C C . TYR B 1 279 ? 32.751 -17.272 12.531 1.00 18.36 ? 279 TYR B C 1 ATOM 5530 O O . TYR B 1 279 ? 33.816 -16.856 12.017 1.00 18.34 ? 279 TYR B O 1 ATOM 5531 C CB . TYR B 1 279 ? 30.908 -15.661 12.947 1.00 18.49 ? 279 TYR B CB 1 ATOM 5532 C CG . TYR B 1 279 ? 31.809 -14.463 13.026 1.00 19.20 ? 279 TYR B CG 1 ATOM 5533 C CD1 . TYR B 1 279 ? 31.736 -13.437 12.069 1.00 21.74 ? 279 TYR B CD1 1 ATOM 5534 C CD2 . TYR B 1 279 ? 32.723 -14.340 14.045 1.00 20.51 ? 279 TYR B CD2 1 ATOM 5535 C CE1 . TYR B 1 279 ? 32.589 -12.293 12.131 1.00 21.80 ? 279 TYR B CE1 1 ATOM 5536 C CE2 . TYR B 1 279 ? 33.586 -13.212 14.122 1.00 21.43 ? 279 TYR B CE2 1 ATOM 5537 C CZ . TYR B 1 279 ? 33.511 -12.190 13.179 1.00 22.49 ? 279 TYR B CZ 1 ATOM 5538 O OH . TYR B 1 279 ? 34.357 -11.083 13.294 1.00 22.58 ? 279 TYR B OH 1 ATOM 5539 N N . TYR B 1 280 ? 32.716 -18.157 13.536 1.00 18.33 ? 280 TYR B N 1 ATOM 5540 C CA . TYR B 1 280 ? 33.966 -18.647 14.120 1.00 17.86 ? 280 TYR B CA 1 ATOM 5541 C C . TYR B 1 280 ? 34.523 -19.843 13.356 1.00 18.53 ? 280 TYR B C 1 ATOM 5542 O O . TYR B 1 280 ? 35.709 -20.148 13.485 1.00 18.53 ? 280 TYR B O 1 ATOM 5543 C CB . TYR B 1 280 ? 33.868 -18.855 15.670 1.00 17.66 ? 280 TYR B CB 1 ATOM 5544 C CG . TYR B 1 280 ? 33.840 -17.517 16.371 1.00 15.05 ? 280 TYR B CG 1 ATOM 5545 C CD1 . TYR B 1 280 ? 34.993 -16.707 16.405 1.00 13.87 ? 280 TYR B CD1 1 ATOM 5546 C CD2 . TYR B 1 280 ? 32.638 -17.018 16.939 1.00 13.71 ? 280 TYR B CD2 1 ATOM 5547 C CE1 . TYR B 1 280 ? 34.960 -15.406 16.991 1.00 14.32 ? 280 TYR B CE1 1 ATOM 5548 C CE2 . TYR B 1 280 ? 32.581 -15.756 17.528 1.00 10.04 ? 280 TYR B CE2 1 ATOM 5549 C CZ . TYR B 1 280 ? 33.746 -14.927 17.554 1.00 13.98 ? 280 TYR B CZ 1 ATOM 5550 O OH . TYR B 1 280 ? 33.714 -13.626 18.108 1.00 10.58 ? 280 TYR B OH 1 ATOM 5551 N N . GLY B 1 281 ? 33.671 -20.507 12.556 1.00 18.51 ? 281 GLY B N 1 ATOM 5552 C CA . GLY B 1 281 ? 34.089 -21.650 11.749 1.00 17.54 ? 281 GLY B CA 1 ATOM 5553 C C . GLY B 1 281 ? 34.805 -21.225 10.474 1.00 17.85 ? 281 GLY B C 1 ATOM 5554 O O . GLY B 1 281 ? 35.880 -21.730 10.152 1.00 16.85 ? 281 GLY B O 1 ATOM 5555 N N . HIS B 1 282 ? 34.208 -20.284 9.746 1.00 18.27 ? 282 HIS B N 1 ATOM 5556 C CA . HIS B 1 282 ? 34.644 -19.987 8.384 1.00 18.76 ? 282 HIS B CA 1 ATOM 5557 C C . HIS B 1 282 ? 34.768 -18.485 8.085 1.00 18.97 ? 282 HIS B C 1 ATOM 5558 O O . HIS B 1 282 ? 35.441 -18.068 7.112 1.00 18.54 ? 282 HIS B O 1 ATOM 5559 C CB . HIS B 1 282 ? 33.725 -20.706 7.392 1.00 18.63 ? 282 HIS B CB 1 ATOM 5560 C CG . HIS B 1 282 ? 33.704 -22.187 7.587 1.00 20.46 ? 282 HIS B CG 1 ATOM 5561 N ND1 . HIS B 1 282 ? 34.569 -23.031 6.920 1.00 21.62 ? 282 HIS B ND1 1 ATOM 5562 C CD2 . HIS B 1 282 ? 32.981 -22.970 8.431 1.00 21.76 ? 282 HIS B CD2 1 ATOM 5563 C CE1 . HIS B 1 282 ? 34.366 -24.273 7.324 1.00 22.89 ? 282 HIS B CE1 1 ATOM 5564 N NE2 . HIS B 1 282 ? 33.407 -24.264 8.241 1.00 25.23 ? 282 HIS B NE2 1 ATOM 5565 N N . GLY B 1 283 ? 34.118 -17.675 8.915 1.00 18.38 ? 283 GLY B N 1 ATOM 5566 C CA . GLY B 1 283 ? 34.182 -16.228 8.739 1.00 17.70 ? 283 GLY B CA 1 ATOM 5567 C C . GLY B 1 283 ? 35.369 -15.575 9.408 1.00 17.69 ? 283 GLY B C 1 ATOM 5568 O O . GLY B 1 283 ? 36.392 -16.222 9.721 1.00 17.31 ? 283 GLY B O 1 ATOM 5569 N N . ALA B 1 284 ? 35.222 -14.269 9.608 1.00 17.52 ? 284 ALA B N 1 ATOM 5570 C CA . ALA B 1 284 ? 36.263 -13.406 10.207 1.00 17.94 ? 284 ALA B CA 1 ATOM 5571 C C . ALA B 1 284 ? 36.733 -13.852 11.587 1.00 17.70 ? 284 ALA B C 1 ATOM 5572 O O . ALA B 1 284 ? 37.880 -13.629 11.951 1.00 17.43 ? 284 ALA B O 1 ATOM 5573 C CB . ALA B 1 284 ? 35.779 -11.952 10.289 1.00 17.33 ? 284 ALA B CB 1 ATOM 5574 N N . GLY B 1 285 ? 35.827 -14.436 12.363 1.00 17.74 ? 285 GLY B N 1 ATOM 5575 C CA . GLY B 1 285 ? 36.208 -14.949 13.672 1.00 18.10 ? 285 GLY B CA 1 ATOM 5576 C C . GLY B 1 285 ? 37.262 -16.052 13.690 1.00 17.64 ? 285 GLY B C 1 ATOM 5577 O O . GLY B 1 285 ? 37.839 -16.339 14.744 1.00 18.25 ? 285 GLY B O 1 ATOM 5578 N N . ASN B 1 286 ? 37.493 -16.705 12.557 1.00 17.11 ? 286 ASN B N 1 ATOM 5579 C CA . ASN B 1 286 ? 38.476 -17.783 12.526 1.00 16.86 ? 286 ASN B CA 1 ATOM 5580 C C . ASN B 1 286 ? 39.716 -17.329 11.750 1.00 17.03 ? 286 ASN B C 1 ATOM 5581 O O . ASN B 1 286 ? 39.599 -16.827 10.670 1.00 16.37 ? 286 ASN B O 1 ATOM 5582 C CB . ASN B 1 286 ? 37.866 -19.024 11.898 1.00 15.83 ? 286 ASN B CB 1 ATOM 5583 C CG . ASN B 1 286 ? 38.839 -20.146 11.815 1.00 17.86 ? 286 ASN B CG 1 ATOM 5584 O OD1 . ASN B 1 286 ? 39.880 -20.062 11.108 1.00 23.28 ? 286 ASN B OD1 1 ATOM 5585 N ND2 . ASN B 1 286 ? 38.564 -21.205 12.544 1.00 13.73 ? 286 ASN B ND2 1 ATOM 5586 N N . PRO B 1 287 ? 40.915 -17.536 12.292 1.00 18.06 ? 287 PRO B N 1 ATOM 5587 C CA . PRO B 1 287 ? 42.076 -16.861 11.669 1.00 18.37 ? 287 PRO B CA 1 ATOM 5588 C C . PRO B 1 287 ? 42.316 -17.278 10.246 1.00 18.32 ? 287 PRO B C 1 ATOM 5589 O O . PRO B 1 287 ? 42.997 -16.570 9.524 1.00 19.53 ? 287 PRO B O 1 ATOM 5590 C CB . PRO B 1 287 ? 43.263 -17.326 12.503 1.00 17.92 ? 287 PRO B CB 1 ATOM 5591 C CG . PRO B 1 287 ? 42.765 -18.521 13.287 1.00 18.72 ? 287 PRO B CG 1 ATOM 5592 C CD . PRO B 1 287 ? 41.297 -18.456 13.384 1.00 18.16 ? 287 PRO B CD 1 ATOM 5593 N N . LEU B 1 288 ? 41.789 -18.427 9.844 1.00 18.12 ? 288 LEU B N 1 ATOM 5594 C CA . LEU B 1 288 ? 42.066 -18.958 8.497 1.00 17.23 ? 288 LEU B CA 1 ATOM 5595 C C . LEU B 1 288 ? 40.799 -19.050 7.665 1.00 16.48 ? 288 LEU B C 1 ATOM 5596 O O . LEU B 1 288 ? 40.774 -19.632 6.581 1.00 17.48 ? 288 LEU B O 1 ATOM 5597 C CB . LEU B 1 288 ? 42.727 -20.330 8.604 1.00 17.43 ? 288 LEU B CB 1 ATOM 5598 C CG . LEU B 1 288 ? 44.229 -20.331 8.851 1.00 19.32 ? 288 LEU B CG 1 ATOM 5599 C CD1 . LEU B 1 288 ? 44.776 -21.722 9.237 1.00 18.95 ? 288 LEU B CD1 1 ATOM 5600 C CD2 . LEU B 1 288 ? 44.899 -19.812 7.560 1.00 21.71 ? 288 LEU B CD2 1 ATOM 5601 N N . GLY B 1 289 ? 39.719 -18.502 8.191 1.00 15.67 ? 289 GLY B N 1 ATOM 5602 C CA . GLY B 1 289 ? 38.414 -18.615 7.544 1.00 14.08 ? 289 GLY B CA 1 ATOM 5603 C C . GLY B 1 289 ? 38.383 -17.815 6.243 1.00 13.26 ? 289 GLY B C 1 ATOM 5604 O O . GLY B 1 289 ? 38.168 -18.401 5.191 1.00 12.63 ? 289 GLY B O 1 ATOM 5605 N N . PRO B 1 290 ? 38.603 -16.474 6.314 1.00 12.64 ? 290 PRO B N 1 ATOM 5606 C CA . PRO B 1 290 ? 38.572 -15.668 5.094 1.00 12.33 ? 290 PRO B CA 1 ATOM 5607 C C . PRO B 1 290 ? 39.671 -16.136 4.118 1.00 13.45 ? 290 PRO B C 1 ATOM 5608 O O . PRO B 1 290 ? 39.591 -15.899 2.888 1.00 11.88 ? 290 PRO B O 1 ATOM 5609 C CB . PRO B 1 290 ? 38.893 -14.236 5.581 1.00 11.39 ? 290 PRO B CB 1 ATOM 5610 C CG . PRO B 1 290 ? 38.713 -14.229 7.080 1.00 12.23 ? 290 PRO B CG 1 ATOM 5611 C CD . PRO B 1 290 ? 39.050 -15.677 7.485 1.00 12.55 ? 290 PRO B CD 1 ATOM 5612 N N . THR B 1 291 ? 40.679 -16.821 4.655 1.00 13.52 ? 291 THR B N 1 ATOM 5613 C CA . THR B 1 291 ? 41.717 -17.329 3.782 1.00 14.73 ? 291 THR B CA 1 ATOM 5614 C C . THR B 1 291 ? 41.135 -18.461 2.902 1.00 15.30 ? 291 THR B C 1 ATOM 5615 O O . THR B 1 291 ? 41.636 -18.740 1.811 1.00 15.73 ? 291 THR B O 1 ATOM 5616 C CB . THR B 1 291 ? 42.981 -17.749 4.570 1.00 14.77 ? 291 THR B CB 1 ATOM 5617 O OG1 . THR B 1 291 ? 43.849 -16.606 4.716 1.00 13.87 ? 291 THR B OG1 1 ATOM 5618 C CG2 . THR B 1 291 ? 43.713 -18.874 3.851 1.00 12.13 ? 291 THR B CG2 1 ATOM 5619 N N . GLN B 1 292 ? 40.063 -19.070 3.373 1.00 14.77 ? 292 GLN B N 1 ATOM 5620 C CA . GLN B 1 292 ? 39.433 -20.129 2.614 1.00 15.50 ? 292 GLN B CA 1 ATOM 5621 C C . GLN B 1 292 ? 38.764 -19.534 1.372 1.00 15.31 ? 292 GLN B C 1 ATOM 5622 O O . GLN B 1 292 ? 38.584 -20.222 0.393 1.00 13.73 ? 292 GLN B O 1 ATOM 5623 C CB . GLN B 1 292 ? 38.457 -20.961 3.490 1.00 15.19 ? 292 GLN B CB 1 ATOM 5624 C CG . GLN B 1 292 ? 39.180 -21.612 4.661 1.00 14.83 ? 292 GLN B CG 1 ATOM 5625 C CD . GLN B 1 292 ? 40.426 -22.407 4.211 1.00 13.94 ? 292 GLN B CD 1 ATOM 5626 O OE1 . GLN B 1 292 ? 40.294 -23.443 3.548 1.00 16.23 ? 292 GLN B OE1 1 ATOM 5627 N NE2 . GLN B 1 292 ? 41.609 -21.970 4.611 1.00 8.97 ? 292 GLN B NE2 1 ATOM 5628 N N . GLY B 1 293 ? 38.460 -18.229 1.417 1.00 16.34 ? 293 GLY B N 1 ATOM 5629 C CA . GLY B 1 293 ? 37.767 -17.543 0.308 1.00 15.39 ? 293 GLY B CA 1 ATOM 5630 C C . GLY B 1 293 ? 38.673 -16.851 -0.692 1.00 15.61 ? 293 GLY B C 1 ATOM 5631 O O . GLY B 1 293 ? 38.184 -16.194 -1.629 1.00 15.34 ? 293 GLY B O 1 ATOM 5632 N N . VAL B 1 294 ? 39.997 -16.946 -0.523 1.00 16.36 ? 294 VAL B N 1 ATOM 5633 C CA . VAL B 1 294 ? 40.836 -16.091 -1.368 1.00 16.15 ? 294 VAL B CA 1 ATOM 5634 C C . VAL B 1 294 ? 40.971 -16.601 -2.786 1.00 15.17 ? 294 VAL B C 1 ATOM 5635 O O . VAL B 1 294 ? 41.119 -15.808 -3.703 1.00 15.51 ? 294 VAL B O 1 ATOM 5636 C CB . VAL B 1 294 ? 42.195 -15.573 -0.721 1.00 16.98 ? 294 VAL B CB 1 ATOM 5637 C CG1 . VAL B 1 294 ? 42.209 -15.778 0.752 1.00 17.24 ? 294 VAL B CG1 1 ATOM 5638 C CG2 . VAL B 1 294 ? 43.412 -16.144 -1.413 1.00 15.63 ? 294 VAL B CG2 1 ATOM 5639 N N . GLY B 1 295 ? 40.840 -17.914 -2.973 1.00 15.64 ? 295 GLY B N 1 ATOM 5640 C CA . GLY B 1 295 ? 40.875 -18.533 -4.322 1.00 14.39 ? 295 GLY B CA 1 ATOM 5641 C C . GLY B 1 295 ? 39.745 -18.040 -5.222 1.00 14.06 ? 295 GLY B C 1 ATOM 5642 O O . GLY B 1 295 ? 39.972 -17.639 -6.372 1.00 15.02 ? 295 GLY B O 1 ATOM 5643 N N . TYR B 1 296 ? 38.534 -18.035 -4.693 1.00 12.49 ? 296 TYR B N 1 ATOM 5644 C CA . TYR B 1 296 ? 37.406 -17.610 -5.428 1.00 12.32 ? 296 TYR B CA 1 ATOM 5645 C C . TYR B 1 296 ? 37.462 -16.133 -5.658 1.00 12.77 ? 296 TYR B C 1 ATOM 5646 O O . TYR B 1 296 ? 37.051 -15.667 -6.719 1.00 14.05 ? 296 TYR B O 1 ATOM 5647 C CB . TYR B 1 296 ? 36.117 -17.944 -4.653 1.00 13.56 ? 296 TYR B CB 1 ATOM 5648 C CG . TYR B 1 296 ? 34.863 -17.828 -5.495 1.00 12.46 ? 296 TYR B CG 1 ATOM 5649 C CD1 . TYR B 1 296 ? 34.509 -18.821 -6.400 1.00 14.13 ? 296 TYR B CD1 1 ATOM 5650 C CD2 . TYR B 1 296 ? 34.047 -16.692 -5.396 1.00 16.13 ? 296 TYR B CD2 1 ATOM 5651 C CE1 . TYR B 1 296 ? 33.348 -18.694 -7.178 1.00 17.42 ? 296 TYR B CE1 1 ATOM 5652 C CE2 . TYR B 1 296 ? 32.899 -16.549 -6.147 1.00 17.22 ? 296 TYR B CE2 1 ATOM 5653 C CZ . TYR B 1 296 ? 32.540 -17.550 -7.049 1.00 19.41 ? 296 TYR B CZ 1 ATOM 5654 O OH . TYR B 1 296 ? 31.370 -17.386 -7.798 1.00 20.28 ? 296 TYR B OH 1 ATOM 5655 N N . ALA B 1 297 ? 37.940 -15.382 -4.674 1.00 12.51 ? 297 ALA B N 1 ATOM 5656 C CA . ALA B 1 297 ? 38.088 -13.943 -4.820 1.00 13.20 ? 297 ALA B CA 1 ATOM 5657 C C . ALA B 1 297 ? 39.043 -13.621 -5.924 1.00 14.03 ? 297 ALA B C 1 ATOM 5658 O O . ALA B 1 297 ? 38.847 -12.638 -6.591 1.00 15.01 ? 297 ALA B O 1 ATOM 5659 C CB . ALA B 1 297 ? 38.549 -13.237 -3.480 1.00 12.41 ? 297 ALA B CB 1 ATOM 5660 N N . ASN B 1 298 ? 40.090 -14.410 -6.130 1.00 14.85 ? 298 ASN B N 1 ATOM 5661 C CA . ASN B 1 298 ? 40.997 -14.106 -7.252 1.00 16.24 ? 298 ASN B CA 1 ATOM 5662 C C . ASN B 1 298 ? 40.404 -14.527 -8.610 1.00 17.37 ? 298 ASN B C 1 ATOM 5663 O O . ASN B 1 298 ? 40.783 -13.958 -9.660 1.00 18.03 ? 298 ASN B O 1 ATOM 5664 C CB . ASN B 1 298 ? 42.392 -14.727 -7.055 1.00 16.27 ? 298 ASN B CB 1 ATOM 5665 C CG . ASN B 1 298 ? 43.159 -14.084 -5.896 1.00 16.94 ? 298 ASN B CG 1 ATOM 5666 O OD1 . ASN B 1 298 ? 43.305 -12.871 -5.835 1.00 15.12 ? 298 ASN B OD1 1 ATOM 5667 N ND2 . ASN B 1 298 ? 43.625 -14.910 -4.958 1.00 15.32 ? 298 ASN B ND2 1 ATOM 5668 N N . GLU B 1 299 ? 39.471 -15.496 -8.603 1.00 16.75 ? 299 GLU B N 1 ATOM 5669 C CA . GLU B 1 299 ? 38.758 -15.868 -9.847 1.00 15.98 ? 299 GLU B CA 1 ATOM 5670 C C . GLU B 1 299 ? 37.757 -14.787 -10.175 1.00 16.70 ? 299 GLU B C 1 ATOM 5671 O O . GLU B 1 299 ? 37.640 -14.354 -11.340 1.00 16.59 ? 299 GLU B O 1 ATOM 5672 C CB . GLU B 1 299 ? 38.079 -17.223 -9.740 1.00 15.43 ? 299 GLU B CB 1 ATOM 5673 C CG . GLU B 1 299 ? 39.120 -18.346 -9.630 1.00 14.68 ? 299 GLU B CG 1 ATOM 5674 C CD . GLU B 1 299 ? 38.495 -19.691 -9.554 1.00 17.00 ? 299 GLU B CD 1 ATOM 5675 O OE1 . GLU B 1 299 ? 37.441 -19.824 -8.874 1.00 16.66 ? 299 GLU B OE1 1 ATOM 5676 O OE2 . GLU B 1 299 ? 39.045 -20.604 -10.207 1.00 18.28 ? 299 GLU B OE2 1 ATOM 5677 N N . LEU B 1 300 ? 37.066 -14.282 -9.156 1.00 16.77 ? 300 LEU B N 1 ATOM 5678 C CA . LEU B 1 300 ? 36.216 -13.151 -9.433 1.00 17.28 ? 300 LEU B CA 1 ATOM 5679 C C . LEU B 1 300 ? 37.021 -11.954 -9.974 1.00 17.32 ? 300 LEU B C 1 ATOM 5680 O O . LEU B 1 300 ? 36.540 -11.272 -10.865 1.00 19.32 ? 300 LEU B O 1 ATOM 5681 C CB . LEU B 1 300 ? 35.403 -12.746 -8.211 1.00 17.48 ? 300 LEU B CB 1 ATOM 5682 C CG . LEU B 1 300 ? 34.643 -11.450 -8.452 1.00 16.90 ? 300 LEU B CG 1 ATOM 5683 C CD1 . LEU B 1 300 ? 33.531 -11.709 -9.462 1.00 16.04 ? 300 LEU B CD1 1 ATOM 5684 C CD2 . LEU B 1 300 ? 34.076 -10.908 -7.132 1.00 14.64 ? 300 LEU B CD2 1 ATOM 5685 N N . ILE B 1 301 ? 38.242 -11.725 -9.493 1.00 16.98 ? 301 ILE B N 1 ATOM 5686 C CA . ILE B 1 301 ? 39.049 -10.598 -9.958 1.00 17.18 ? 301 ILE B CA 1 ATOM 5687 C C . ILE B 1 301 ? 39.413 -10.780 -11.439 1.00 17.54 ? 301 ILE B C 1 ATOM 5688 O O . ILE B 1 301 ? 39.199 -9.867 -12.253 1.00 18.52 ? 301 ILE B O 1 ATOM 5689 C CB . ILE B 1 301 ? 40.279 -10.330 -9.036 1.00 17.04 ? 301 ILE B CB 1 ATOM 5690 C CG1 . ILE B 1 301 ? 39.872 -9.564 -7.788 1.00 16.23 ? 301 ILE B CG1 1 ATOM 5691 C CG2 . ILE B 1 301 ? 41.426 -9.602 -9.760 1.00 16.47 ? 301 ILE B CG2 1 ATOM 5692 C CD1 . ILE B 1 301 ? 40.913 -9.702 -6.649 1.00 18.68 ? 301 ILE B CD1 1 ATOM 5693 N N . ALA B 1 302 ? 39.914 -11.963 -11.784 1.00 17.71 ? 302 ALA B N 1 ATOM 5694 C CA . ALA B 1 302 ? 40.119 -12.369 -13.185 1.00 17.82 ? 302 ALA B CA 1 ATOM 5695 C C . ALA B 1 302 ? 38.931 -12.036 -14.105 1.00 18.18 ? 302 ALA B C 1 ATOM 5696 O O . ALA B 1 302 ? 39.100 -11.431 -15.169 1.00 17.93 ? 302 ALA B O 1 ATOM 5697 C CB . ALA B 1 302 ? 40.432 -13.842 -13.249 1.00 17.24 ? 302 ALA B CB 1 ATOM 5698 N N . ARG B 1 303 ? 37.737 -12.434 -13.671 1.00 19.07 ? 303 ARG B N 1 ATOM 5699 C CA . ARG B 1 303 ? 36.513 -12.257 -14.436 1.00 18.68 ? 303 ARG B CA 1 ATOM 5700 C C . ARG B 1 303 ? 36.132 -10.791 -14.590 1.00 19.62 ? 303 ARG B C 1 ATOM 5701 O O . ARG B 1 303 ? 35.671 -10.377 -15.643 1.00 20.38 ? 303 ARG B O 1 ATOM 5702 C CB . ARG B 1 303 ? 35.371 -13.044 -13.792 1.00 18.26 ? 303 ARG B CB 1 ATOM 5703 C CG . ARG B 1 303 ? 35.492 -14.500 -14.031 1.00 15.27 ? 303 ARG B CG 1 ATOM 5704 C CD . ARG B 1 303 ? 34.560 -15.338 -13.206 1.00 13.44 ? 303 ARG B CD 1 ATOM 5705 N NE . ARG B 1 303 ? 34.577 -16.753 -13.673 1.00 12.13 ? 303 ARG B NE 1 ATOM 5706 C CZ . ARG B 1 303 ? 33.901 -17.770 -13.110 1.00 14.64 ? 303 ARG B CZ 1 ATOM 5707 N NH1 . ARG B 1 303 ? 33.127 -17.557 -12.036 1.00 15.61 ? 303 ARG B NH1 1 ATOM 5708 N NH2 . ARG B 1 303 ? 33.939 -19.011 -13.659 1.00 9.33 ? 303 ARG B NH2 1 ATOM 5709 N N . LEU B 1 304 ? 36.315 -9.996 -13.545 1.00 20.59 ? 304 LEU B N 1 ATOM 5710 C CA . LEU B 1 304 ? 35.938 -8.587 -13.609 1.00 19.99 ? 304 LEU B CA 1 ATOM 5711 C C . LEU B 1 304 ? 36.917 -7.829 -14.467 1.00 20.73 ? 304 LEU B C 1 ATOM 5712 O O . LEU B 1 304 ? 36.540 -6.812 -15.074 1.00 20.85 ? 304 LEU B O 1 ATOM 5713 C CB . LEU B 1 304 ? 35.947 -7.954 -12.228 1.00 19.57 ? 304 LEU B CB 1 ATOM 5714 C CG . LEU B 1 304 ? 34.952 -8.303 -11.144 1.00 19.86 ? 304 LEU B CG 1 ATOM 5715 C CD1 . LEU B 1 304 ? 35.314 -7.451 -9.929 1.00 16.61 ? 304 LEU B CD1 1 ATOM 5716 C CD2 . LEU B 1 304 ? 33.488 -8.078 -11.573 1.00 20.43 ? 304 LEU B CD2 1 ATOM 5717 N N . THR B 1 305 ? 38.170 -8.305 -14.481 1.00 21.03 ? 305 THR B N 1 ATOM 5718 C CA . THR B 1 305 ? 39.255 -7.659 -15.234 1.00 22.00 ? 305 THR B CA 1 ATOM 5719 C C . THR B 1 305 ? 39.588 -8.381 -16.519 1.00 22.54 ? 305 THR B C 1 ATOM 5720 O O . THR B 1 305 ? 40.521 -7.970 -17.206 1.00 22.64 ? 305 THR B O 1 ATOM 5721 C CB . THR B 1 305 ? 40.601 -7.567 -14.431 1.00 21.65 ? 305 THR B CB 1 ATOM 5722 O OG1 . THR B 1 305 ? 40.913 -8.856 -13.910 1.00 21.97 ? 305 THR B OG1 1 ATOM 5723 C CG2 . THR B 1 305 ? 40.517 -6.555 -13.271 1.00 21.33 ? 305 THR B CG2 1 ATOM 5724 N N . HIS B 1 306 ? 38.866 -9.469 -16.830 1.00 23.34 ? 306 HIS B N 1 ATOM 5725 C CA . HIS B 1 306 ? 39.086 -10.217 -18.077 1.00 23.41 ? 306 HIS B CA 1 ATOM 5726 C C . HIS B 1 306 ? 40.550 -10.461 -18.296 1.00 24.19 ? 306 HIS B C 1 ATOM 5727 O O . HIS B 1 306 ? 41.017 -10.314 -19.442 1.00 23.45 ? 306 HIS B O 1 ATOM 5728 C CB . HIS B 1 306 ? 38.579 -9.424 -19.274 1.00 23.30 ? 306 HIS B CB 1 ATOM 5729 C CG . HIS B 1 306 ? 37.293 -8.728 -19.014 1.00 24.70 ? 306 HIS B CG 1 ATOM 5730 N ND1 . HIS B 1 306 ? 36.092 -9.404 -18.912 1.00 25.44 ? 306 HIS B ND1 1 ATOM 5731 C CD2 . HIS B 1 306 ? 37.019 -7.418 -18.787 1.00 25.62 ? 306 HIS B CD2 1 ATOM 5732 C CE1 . HIS B 1 306 ? 35.129 -8.532 -18.648 1.00 26.55 ? 306 HIS B CE1 1 ATOM 5733 N NE2 . HIS B 1 306 ? 35.663 -7.321 -18.566 1.00 25.47 ? 306 HIS B NE2 1 ATOM 5734 N N . SER B 1 307 ? 41.256 -10.804 -17.201 1.00 24.64 ? 307 SER B N 1 ATOM 5735 C CA . SER B 1 307 ? 42.707 -11.106 -17.203 1.00 24.87 ? 307 SER B CA 1 ATOM 5736 C C . SER B 1 307 ? 42.911 -12.471 -16.582 1.00 24.83 ? 307 SER B C 1 ATOM 5737 O O . SER B 1 307 ? 41.984 -12.992 -16.011 1.00 24.84 ? 307 SER B O 1 ATOM 5738 C CB . SER B 1 307 ? 43.470 -10.078 -16.359 1.00 25.08 ? 307 SER B CB 1 ATOM 5739 O OG . SER B 1 307 ? 43.210 -8.789 -16.844 1.00 25.01 ? 307 SER B OG 1 ATOM 5740 N N . PRO B 1 308 ? 44.116 -13.059 -16.701 1.00 25.20 ? 308 PRO B N 1 ATOM 5741 C CA . PRO B 1 308 ? 44.462 -14.326 -16.023 1.00 25.86 ? 308 PRO B CA 1 ATOM 5742 C C . PRO B 1 308 ? 44.299 -14.334 -14.486 1.00 26.60 ? 308 PRO B C 1 ATOM 5743 O O . PRO B 1 308 ? 44.484 -13.307 -13.836 1.00 26.93 ? 308 PRO B O 1 ATOM 5744 C CB . PRO B 1 308 ? 45.947 -14.511 -16.363 1.00 26.02 ? 308 PRO B CB 1 ATOM 5745 C CG . PRO B 1 308 ? 46.111 -13.800 -17.727 1.00 26.53 ? 308 PRO B CG 1 ATOM 5746 C CD . PRO B 1 308 ? 45.087 -12.695 -17.755 1.00 25.23 ? 308 PRO B CD 1 ATOM 5747 N N . VAL B 1 309 ? 43.974 -15.494 -13.919 1.00 27.11 ? 309 VAL B N 1 ATOM 5748 C CA . VAL B 1 309 ? 43.871 -15.676 -12.478 1.00 27.34 ? 309 VAL B CA 1 ATOM 5749 C C . VAL B 1 309 ? 45.270 -15.510 -11.902 1.00 28.28 ? 309 VAL B C 1 ATOM 5750 O O . VAL B 1 309 ? 46.233 -16.054 -12.429 1.00 28.70 ? 309 VAL B O 1 ATOM 5751 C CB . VAL B 1 309 ? 43.337 -17.088 -12.128 1.00 27.26 ? 309 VAL B CB 1 ATOM 5752 C CG1 . VAL B 1 309 ? 42.976 -17.206 -10.667 1.00 25.18 ? 309 VAL B CG1 1 ATOM 5753 C CG2 . VAL B 1 309 ? 42.130 -17.381 -12.966 1.00 26.76 ? 309 VAL B CG2 1 ATOM 5754 N N . HIS B 1 310 ? 45.378 -14.713 -10.847 1.00 28.97 ? 310 HIS B N 1 ATOM 5755 C CA . HIS B 1 310 ? 46.582 -14.704 -10.038 1.00 29.80 ? 310 HIS B CA 1 ATOM 5756 C C . HIS B 1 310 ? 46.235 -15.205 -8.640 1.00 29.21 ? 310 HIS B C 1 ATOM 5757 O O . HIS B 1 310 ? 45.599 -14.492 -7.829 1.00 29.35 ? 310 HIS B O 1 ATOM 5758 C CB . HIS B 1 310 ? 47.266 -13.344 -10.053 1.00 30.07 ? 310 HIS B CB 1 ATOM 5759 C CG . HIS B 1 310 ? 47.517 -12.852 -11.434 1.00 34.98 ? 310 HIS B CG 1 ATOM 5760 N ND1 . HIS B 1 310 ? 46.828 -11.786 -11.984 1.00 37.97 ? 310 HIS B ND1 1 ATOM 5761 C CD2 . HIS B 1 310 ? 48.329 -13.331 -12.413 1.00 37.56 ? 310 HIS B CD2 1 ATOM 5762 C CE1 . HIS B 1 310 ? 47.229 -11.613 -13.237 1.00 39.44 ? 310 HIS B CE1 1 ATOM 5763 N NE2 . HIS B 1 310 ? 48.135 -12.539 -13.522 1.00 39.22 ? 310 HIS B NE2 1 ATOM 5764 N N . ASP B 1 311 ? 46.639 -16.459 -8.408 1.00 28.47 ? 311 ASP B N 1 ATOM 5765 C CA . ASP B 1 311 ? 46.334 -17.193 -7.188 1.00 28.03 ? 311 ASP B CA 1 ATOM 5766 C C . ASP B 1 311 ? 47.205 -18.423 -7.003 1.00 27.69 ? 311 ASP B C 1 ATOM 5767 O O . ASP B 1 311 ? 47.334 -19.256 -7.900 1.00 28.13 ? 311 ASP B O 1 ATOM 5768 C CB . ASP B 1 311 ? 44.877 -17.653 -7.223 1.00 28.00 ? 311 ASP B CB 1 ATOM 5769 C CG . ASP B 1 311 ? 44.472 -18.383 -5.969 1.00 27.48 ? 311 ASP B CG 1 ATOM 5770 O OD1 . ASP B 1 311 ? 44.172 -17.711 -4.964 1.00 28.10 ? 311 ASP B OD1 1 ATOM 5771 O OD2 . ASP B 1 311 ? 44.470 -19.624 -5.986 1.00 27.33 ? 311 ASP B OD2 1 ATOM 5772 N N . ASP B 1 312 ? 47.783 -18.573 -5.826 1.00 27.57 ? 312 ASP B N 1 ATOM 5773 C CA A ASP B 1 312 ? 48.459 -19.849 -5.505 0.50 27.54 ? 312 ASP B CA 1 ATOM 5774 C CA B ASP B 1 312 ? 48.494 -19.801 -5.496 0.50 26.99 ? 312 ASP B CA 1 ATOM 5775 C C . ASP B 1 312 ? 47.951 -20.449 -4.201 1.00 26.80 ? 312 ASP B C 1 ATOM 5776 O O . ASP B 1 312 ? 48.661 -21.191 -3.525 1.00 26.70 ? 312 ASP B O 1 ATOM 5777 C CB A ASP B 1 312 ? 49.993 -19.758 -5.503 0.50 28.03 ? 312 ASP B CB 1 ATOM 5778 C CB B ASP B 1 312 ? 50.004 -19.532 -5.468 0.50 27.01 ? 312 ASP B CB 1 ATOM 5779 C CG A ASP B 1 312 ? 50.660 -21.144 -5.376 0.50 31.05 ? 312 ASP B CG 1 ATOM 5780 C CG B ASP B 1 312 ? 50.529 -19.031 -6.819 0.50 27.73 ? 312 ASP B CG 1 ATOM 5781 O OD1 A ASP B 1 312 ? 50.131 -22.117 -5.962 0.50 33.62 ? 312 ASP B OD1 1 ATOM 5782 O OD1 B ASP B 1 312 ? 50.522 -19.826 -7.784 0.50 29.47 ? 312 ASP B OD1 1 ATOM 5783 O OD2 A ASP B 1 312 ? 51.694 -21.272 -4.672 0.50 33.93 ? 312 ASP B OD2 1 ATOM 5784 O OD2 B ASP B 1 312 ? 50.911 -17.842 -6.929 0.50 27.55 ? 312 ASP B OD2 1 ATOM 5785 N N . THR B 1 313 ? 46.686 -20.167 -3.877 1.00 25.16 ? 313 THR B N 1 ATOM 5786 C CA . THR B 1 313 ? 46.057 -20.780 -2.714 1.00 23.30 ? 313 THR B CA 1 ATOM 5787 C C . THR B 1 313 ? 45.181 -22.017 -3.105 1.00 24.27 ? 313 THR B C 1 ATOM 5788 O O . THR B 1 313 ? 45.682 -23.167 -3.167 1.00 23.34 ? 313 THR B O 1 ATOM 5789 C CB . THR B 1 313 ? 45.227 -19.763 -1.945 1.00 22.82 ? 313 THR B CB 1 ATOM 5790 O OG1 . THR B 1 313 ? 43.990 -19.541 -2.626 1.00 17.46 ? 313 THR B OG1 1 ATOM 5791 C CG2 . THR B 1 313 ? 46.006 -18.448 -1.775 1.00 21.39 ? 313 THR B CG2 1 ATOM 5792 N N . SER B 1 314 ? 43.896 -21.764 -3.407 1.00 24.15 ? 314 SER B N 1 ATOM 5793 C CA . SER B 1 314 ? 42.916 -22.839 -3.569 1.00 23.99 ? 314 SER B CA 1 ATOM 5794 C C . SER B 1 314 ? 42.538 -23.153 -4.993 1.00 24.25 ? 314 SER B C 1 ATOM 5795 O O . SER B 1 314 ? 41.802 -24.125 -5.208 1.00 24.80 ? 314 SER B O 1 ATOM 5796 C CB . SER B 1 314 ? 41.642 -22.544 -2.785 1.00 23.41 ? 314 SER B CB 1 ATOM 5797 O OG . SER B 1 314 ? 40.984 -21.442 -3.351 1.00 22.74 ? 314 SER B OG 1 ATOM 5798 N N . SER B 1 315 ? 43.004 -22.359 -5.954 1.00 24.23 ? 315 SER B N 1 ATOM 5799 C CA . SER B 1 315 ? 42.650 -22.595 -7.360 1.00 25.08 ? 315 SER B CA 1 ATOM 5800 C C . SER B 1 315 ? 43.421 -23.722 -8.060 1.00 26.08 ? 315 SER B C 1 ATOM 5801 O O . SER B 1 315 ? 44.620 -23.952 -7.811 1.00 26.75 ? 315 SER B O 1 ATOM 5802 C CB . SER B 1 315 ? 42.791 -21.327 -8.191 1.00 24.50 ? 315 SER B CB 1 ATOM 5803 O OG . SER B 1 315 ? 44.156 -20.971 -8.320 1.00 26.89 ? 315 SER B OG 1 ATOM 5804 N N . ASN B 1 316 ? 42.731 -24.406 -8.961 1.00 26.65 ? 316 ASN B N 1 ATOM 5805 C CA . ASN B 1 316 ? 43.356 -25.366 -9.814 1.00 27.59 ? 316 ASN B CA 1 ATOM 5806 C C . ASN B 1 316 ? 43.884 -24.680 -11.090 1.00 28.07 ? 316 ASN B C 1 ATOM 5807 O O . ASN B 1 316 ? 43.106 -24.116 -11.871 1.00 28.85 ? 316 ASN B O 1 ATOM 5808 C CB . ASN B 1 316 ? 42.349 -26.462 -10.131 1.00 27.77 ? 316 ASN B CB 1 ATOM 5809 C CG . ASN B 1 316 ? 42.924 -27.544 -11.044 1.00 29.49 ? 316 ASN B CG 1 ATOM 5810 O OD1 . ASN B 1 316 ? 43.710 -27.252 -11.945 1.00 29.41 ? 316 ASN B OD1 1 ATOM 5811 N ND2 . ASN B 1 316 ? 42.522 -28.797 -10.807 1.00 30.69 ? 316 ASN B ND2 1 ATOM 5812 N N . HIS B 1 317 ? 45.205 -24.751 -11.308 1.00 28.15 ? 317 HIS B N 1 ATOM 5813 C CA . HIS B 1 317 ? 45.890 -24.083 -12.425 1.00 27.66 ? 317 HIS B CA 1 ATOM 5814 C C . HIS B 1 317 ? 45.610 -24.674 -13.810 1.00 27.37 ? 317 HIS B C 1 ATOM 5815 O O . HIS B 1 317 ? 45.564 -23.955 -14.812 1.00 26.99 ? 317 HIS B O 1 ATOM 5816 C CB . HIS B 1 317 ? 47.398 -24.072 -12.177 1.00 28.34 ? 317 HIS B CB 1 ATOM 5817 C CG . HIS B 1 317 ? 47.810 -23.132 -11.090 1.00 30.15 ? 317 HIS B CG 1 ATOM 5818 N ND1 . HIS B 1 317 ? 48.156 -21.822 -11.333 1.00 33.97 ? 317 HIS B ND1 1 ATOM 5819 C CD2 . HIS B 1 317 ? 47.860 -23.290 -9.746 1.00 33.02 ? 317 HIS B CD2 1 ATOM 5820 C CE1 . HIS B 1 317 ? 48.434 -21.219 -10.188 1.00 34.07 ? 317 HIS B CE1 1 ATOM 5821 N NE2 . HIS B 1 317 ? 48.259 -22.089 -9.209 1.00 34.36 ? 317 HIS B NE2 1 ATOM 5822 N N . THR B 1 318 ? 45.464 -25.991 -13.864 1.00 26.58 ? 318 THR B N 1 ATOM 5823 C CA . THR B 1 318 ? 44.992 -26.643 -15.053 1.00 26.06 ? 318 THR B CA 1 ATOM 5824 C C . THR B 1 318 ? 43.612 -26.058 -15.450 1.00 25.87 ? 318 THR B C 1 ATOM 5825 O O . THR B 1 318 ? 43.444 -25.547 -16.564 1.00 25.87 ? 318 THR B O 1 ATOM 5826 C CB . THR B 1 318 ? 44.826 -28.159 -14.816 1.00 25.92 ? 318 THR B CB 1 ATOM 5827 O OG1 . THR B 1 318 ? 46.049 -28.720 -14.333 1.00 25.72 ? 318 THR B OG1 1 ATOM 5828 C CG2 . THR B 1 318 ? 44.412 -28.846 -16.077 1.00 25.30 ? 318 THR B CG2 1 ATOM 5829 N N . LEU B 1 319 ? 42.648 -26.166 -14.528 1.00 25.16 ? 319 LEU B N 1 ATOM 5830 C CA . LEU B 1 319 ? 41.291 -25.674 -14.710 1.00 24.28 ? 319 LEU B CA 1 ATOM 5831 C C . LEU B 1 319 ? 41.233 -24.167 -15.079 1.00 24.66 ? 319 LEU B C 1 ATOM 5832 O O . LEU B 1 319 ? 40.494 -23.787 -15.995 1.00 25.16 ? 319 LEU B O 1 ATOM 5833 C CB . LEU B 1 319 ? 40.517 -25.951 -13.442 1.00 23.70 ? 319 LEU B CB 1 ATOM 5834 C CG . LEU B 1 319 ? 39.331 -26.918 -13.452 1.00 23.69 ? 319 LEU B CG 1 ATOM 5835 C CD1 . LEU B 1 319 ? 39.480 -28.027 -14.495 1.00 24.83 ? 319 LEU B CD1 1 ATOM 5836 C CD2 . LEU B 1 319 ? 38.991 -27.462 -12.030 1.00 21.42 ? 319 LEU B CD2 1 ATOM 5837 N N . ASP B 1 320 ? 42.047 -23.322 -14.421 1.00 23.95 ? 320 ASP B N 1 ATOM 5838 C CA . ASP B 1 320 ? 41.958 -21.887 -14.641 1.00 23.31 ? 320 ASP B CA 1 ATOM 5839 C C . ASP B 1 320 ? 42.770 -21.283 -15.779 1.00 23.82 ? 320 ASP B C 1 ATOM 5840 O O . ASP B 1 320 ? 42.465 -20.164 -16.194 1.00 23.54 ? 320 ASP B O 1 ATOM 5841 C CB . ASP B 1 320 ? 42.297 -21.121 -13.365 1.00 22.99 ? 320 ASP B CB 1 ATOM 5842 C CG . ASP B 1 320 ? 41.209 -21.143 -12.389 1.00 20.31 ? 320 ASP B CG 1 ATOM 5843 O OD1 . ASP B 1 320 ? 40.281 -21.977 -12.506 1.00 22.47 ? 320 ASP B OD1 1 ATOM 5844 O OD2 . ASP B 1 320 ? 41.287 -20.337 -11.472 1.00 15.99 ? 320 ASP B OD2 1 ATOM 5845 N N . SER B 1 321 ? 43.820 -21.949 -16.253 1.00 24.27 ? 321 SER B N 1 ATOM 5846 C CA . SER B 1 321 ? 44.696 -21.272 -17.240 1.00 25.47 ? 321 SER B CA 1 ATOM 5847 C C . SER B 1 321 ? 44.247 -21.545 -18.695 1.00 25.87 ? 321 SER B C 1 ATOM 5848 O O . SER B 1 321 ? 44.978 -21.283 -19.671 1.00 25.61 ? 321 SER B O 1 ATOM 5849 C CB . SER B 1 321 ? 46.186 -21.599 -17.002 1.00 25.49 ? 321 SER B CB 1 ATOM 5850 O OG . SER B 1 321 ? 46.423 -22.978 -17.221 1.00 26.88 ? 321 SER B OG 1 ATOM 5851 N N . SER B 1 322 ? 43.010 -22.028 -18.818 1.00 26.59 ? 322 SER B N 1 ATOM 5852 C CA . SER B 1 322 ? 42.475 -22.550 -20.052 1.00 26.95 ? 322 SER B CA 1 ATOM 5853 C C . SER B 1 322 ? 41.078 -21.990 -20.282 1.00 27.11 ? 322 SER B C 1 ATOM 5854 O O . SER B 1 322 ? 40.184 -22.248 -19.456 1.00 27.42 ? 322 SER B O 1 ATOM 5855 C CB . SER B 1 322 ? 42.433 -24.082 -19.977 1.00 26.88 ? 322 SER B CB 1 ATOM 5856 O OG . SER B 1 322 ? 41.305 -24.599 -20.670 1.00 29.22 ? 322 SER B OG 1 ATOM 5857 N N . PRO B 1 323 ? 40.863 -21.271 -21.427 1.00 26.70 ? 323 PRO B N 1 ATOM 5858 C CA . PRO B 1 323 ? 39.591 -20.602 -21.689 1.00 25.92 ? 323 PRO B CA 1 ATOM 5859 C C . PRO B 1 323 ? 38.399 -21.560 -21.624 1.00 25.88 ? 323 PRO B C 1 ATOM 5860 O O . PRO B 1 323 ? 37.355 -21.160 -21.132 1.00 26.95 ? 323 PRO B O 1 ATOM 5861 C CB . PRO B 1 323 ? 39.762 -20.022 -23.091 1.00 25.89 ? 323 PRO B CB 1 ATOM 5862 C CG . PRO B 1 323 ? 41.201 -20.003 -23.337 1.00 27.01 ? 323 PRO B CG 1 ATOM 5863 C CD . PRO B 1 323 ? 41.735 -21.218 -22.607 1.00 27.00 ? 323 PRO B CD 1 ATOM 5864 N N . ALA B 1 324 ? 38.566 -22.817 -22.053 1.00 25.05 ? 324 ALA B N 1 ATOM 5865 C CA . ALA B 1 324 ? 37.513 -23.854 -22.010 1.00 24.08 ? 324 ALA B CA 1 ATOM 5866 C C . ALA B 1 324 ? 36.913 -24.070 -20.630 1.00 23.81 ? 324 ALA B C 1 ATOM 5867 O O . ALA B 1 324 ? 35.708 -24.274 -20.502 1.00 24.28 ? 324 ALA B O 1 ATOM 5868 C CB . ALA B 1 324 ? 38.057 -25.223 -22.527 1.00 23.40 ? 324 ALA B CB 1 ATOM 5869 N N . THR B 1 325 ? 37.772 -24.069 -19.608 1.00 23.23 ? 325 THR B N 1 ATOM 5870 C CA . THR B 1 325 ? 37.377 -24.400 -18.238 1.00 22.27 ? 325 THR B CA 1 ATOM 5871 C C . THR B 1 325 ? 37.417 -23.160 -17.331 1.00 22.28 ? 325 THR B C 1 ATOM 5872 O O . THR B 1 325 ? 36.928 -23.185 -16.200 1.00 22.61 ? 325 THR B O 1 ATOM 5873 C CB . THR B 1 325 ? 38.245 -25.531 -17.649 1.00 22.02 ? 325 THR B CB 1 ATOM 5874 O OG1 . THR B 1 325 ? 39.584 -25.421 -18.154 1.00 21.24 ? 325 THR B OG1 1 ATOM 5875 C CG2 . THR B 1 325 ? 37.707 -26.894 -18.078 1.00 22.27 ? 325 THR B CG2 1 ATOM 5876 N N . PHE B 1 326 ? 38.003 -22.083 -17.826 1.00 20.90 ? 326 PHE B N 1 ATOM 5877 C CA . PHE B 1 326 ? 37.865 -20.808 -17.154 1.00 20.83 ? 326 PHE B CA 1 ATOM 5878 C C . PHE B 1 326 ? 37.807 -19.604 -18.129 1.00 20.60 ? 326 PHE B C 1 ATOM 5879 O O . PHE B 1 326 ? 38.790 -18.856 -18.227 1.00 20.95 ? 326 PHE B O 1 ATOM 5880 C CB . PHE B 1 326 ? 38.970 -20.614 -16.102 1.00 19.71 ? 326 PHE B CB 1 ATOM 5881 C CG . PHE B 1 326 ? 38.698 -19.470 -15.152 1.00 20.33 ? 326 PHE B CG 1 ATOM 5882 C CD1 . PHE B 1 326 ? 37.899 -19.651 -14.024 1.00 19.57 ? 326 PHE B CD1 1 ATOM 5883 C CD2 . PHE B 1 326 ? 39.205 -18.203 -15.402 1.00 19.34 ? 326 PHE B CD2 1 ATOM 5884 C CE1 . PHE B 1 326 ? 37.650 -18.586 -13.160 1.00 18.38 ? 326 PHE B CE1 1 ATOM 5885 C CE2 . PHE B 1 326 ? 38.942 -17.131 -14.543 1.00 19.56 ? 326 PHE B CE2 1 ATOM 5886 C CZ . PHE B 1 326 ? 38.161 -17.321 -13.435 1.00 19.78 ? 326 PHE B CZ 1 ATOM 5887 N N . PRO B 1 327 ? 36.657 -19.394 -18.824 1.00 19.84 ? 327 PRO B N 1 ATOM 5888 C CA . PRO B 1 327 ? 36.636 -18.313 -19.825 1.00 20.10 ? 327 PRO B CA 1 ATOM 5889 C C . PRO B 1 327 ? 36.506 -16.938 -19.165 1.00 19.77 ? 327 PRO B C 1 ATOM 5890 O O . PRO B 1 327 ? 35.812 -16.828 -18.161 1.00 19.58 ? 327 PRO B O 1 ATOM 5891 C CB . PRO B 1 327 ? 35.406 -18.650 -20.693 1.00 19.67 ? 327 PRO B CB 1 ATOM 5892 C CG . PRO B 1 327 ? 34.502 -19.381 -19.790 1.00 19.40 ? 327 PRO B CG 1 ATOM 5893 C CD . PRO B 1 327 ? 35.371 -20.112 -18.781 1.00 19.85 ? 327 PRO B CD 1 ATOM 5894 N N . LEU B 1 328 ? 37.179 -15.924 -19.709 1.00 19.88 ? 328 LEU B N 1 ATOM 5895 C CA . LEU B 1 328 ? 37.290 -14.597 -19.054 1.00 20.60 ? 328 LEU B CA 1 ATOM 5896 C C . LEU B 1 328 ? 36.331 -13.544 -19.568 1.00 20.93 ? 328 LEU B C 1 ATOM 5897 O O . LEU B 1 328 ? 36.307 -12.422 -19.076 1.00 21.25 ? 328 LEU B O 1 ATOM 5898 C CB . LEU B 1 328 ? 38.710 -14.056 -19.220 1.00 19.99 ? 328 LEU B CB 1 ATOM 5899 C CG . LEU B 1 328 ? 39.813 -15.010 -18.782 1.00 22.21 ? 328 LEU B CG 1 ATOM 5900 C CD1 . LEU B 1 328 ? 41.175 -14.577 -19.315 1.00 20.32 ? 328 LEU B CD1 1 ATOM 5901 C CD2 . LEU B 1 328 ? 39.777 -15.056 -17.254 1.00 21.21 ? 328 LEU B CD2 1 ATOM 5902 N N . ASN B 1 329 ? 35.568 -13.887 -20.591 1.00 22.00 ? 329 ASN B N 1 ATOM 5903 C CA . ASN B 1 329 ? 34.800 -12.887 -21.318 1.00 23.40 ? 329 ASN B CA 1 ATOM 5904 C C . ASN B 1 329 ? 33.403 -13.330 -21.550 1.00 22.85 ? 329 ASN B C 1 ATOM 5905 O O . ASN B 1 329 ? 32.753 -12.791 -22.455 1.00 23.12 ? 329 ASN B O 1 ATOM 5906 C CB . ASN B 1 329 ? 35.399 -12.611 -22.700 1.00 24.11 ? 329 ASN B CB 1 ATOM 5907 C CG . ASN B 1 329 ? 36.640 -11.771 -22.629 1.00 28.35 ? 329 ASN B CG 1 ATOM 5908 O OD1 . ASN B 1 329 ? 36.651 -10.719 -21.980 1.00 33.12 ? 329 ASN B OD1 1 ATOM 5909 N ND2 . ASN B 1 329 ? 37.715 -12.235 -23.292 1.00 31.21 ? 329 ASN B ND2 1 ATOM 5910 N N . SER B 1 330 ? 32.941 -14.312 -20.772 1.00 22.16 ? 330 SER B N 1 ATOM 5911 C CA . SER B 1 330 ? 31.545 -14.684 -20.812 1.00 21.70 ? 330 SER B CA 1 ATOM 5912 C C . SER B 1 330 ? 30.997 -13.441 -20.135 1.00 22.34 ? 330 SER B C 1 ATOM 5913 O O . SER B 1 330 ? 31.782 -12.487 -19.768 1.00 23.47 ? 330 SER B O 1 ATOM 5914 C CB . SER B 1 330 ? 31.270 -15.933 -19.966 1.00 21.86 ? 330 SER B CB 1 ATOM 5915 O OG . SER B 1 330 ? 32.251 -16.931 -20.215 1.00 20.50 ? 330 SER B OG 1 ATOM 5916 N N . THR B 1 331 ? 29.695 -13.392 -19.960 1.00 20.48 ? 331 THR B N 1 ATOM 5917 C CA . THR B 1 331 ? 29.169 -12.164 -19.381 1.00 19.71 ? 331 THR B CA 1 ATOM 5918 C C . THR B 1 331 ? 28.405 -12.520 -18.135 1.00 18.84 ? 331 THR B C 1 ATOM 5919 O O . THR B 1 331 ? 28.269 -11.684 -17.201 1.00 18.66 ? 331 THR B O 1 ATOM 5920 C CB . THR B 1 331 ? 28.301 -11.459 -20.434 1.00 20.02 ? 331 THR B CB 1 ATOM 5921 O OG1 . THR B 1 331 ? 29.176 -10.741 -21.298 1.00 19.58 ? 331 THR B OG1 1 ATOM 5922 C CG2 . THR B 1 331 ? 27.273 -10.547 -19.852 1.00 19.11 ? 331 THR B CG2 1 ATOM 5923 N N . LEU B 1 332 ? 27.962 -13.780 -18.130 1.00 16.77 ? 332 LEU B N 1 ATOM 5924 C CA . LEU B 1 332 ? 27.234 -14.374 -17.031 1.00 16.52 ? 332 LEU B CA 1 ATOM 5925 C C . LEU B 1 332 ? 27.907 -15.644 -16.562 1.00 15.71 ? 332 LEU B C 1 ATOM 5926 O O . LEU B 1 332 ? 28.385 -16.441 -17.369 1.00 16.23 ? 332 LEU B O 1 ATOM 5927 C CB . LEU B 1 332 ? 25.785 -14.699 -17.432 1.00 16.42 ? 332 LEU B CB 1 ATOM 5928 C CG . LEU B 1 332 ? 24.986 -13.621 -18.136 1.00 14.43 ? 332 LEU B CG 1 ATOM 5929 C CD1 . LEU B 1 332 ? 23.919 -14.229 -18.978 1.00 13.75 ? 332 LEU B CD1 1 ATOM 5930 C CD2 . LEU B 1 332 ? 24.451 -12.694 -17.159 1.00 13.57 ? 332 LEU B CD2 1 ATOM 5931 N N . TYR B 1 333 ? 27.884 -15.847 -15.252 1.00 14.92 ? 333 TYR B N 1 ATOM 5932 C CA . TYR B 1 333 ? 28.608 -16.926 -14.602 1.00 13.21 ? 333 TYR B CA 1 ATOM 5933 C C . TYR B 1 333 ? 27.723 -17.401 -13.456 1.00 14.16 ? 333 TYR B C 1 ATOM 5934 O O . TYR B 1 333 ? 27.039 -16.609 -12.805 1.00 13.27 ? 333 TYR B O 1 ATOM 5935 C CB . TYR B 1 333 ? 29.900 -16.425 -14.064 1.00 12.70 ? 333 TYR B CB 1 ATOM 5936 C CG . TYR B 1 333 ? 30.955 -16.058 -15.095 1.00 12.28 ? 333 TYR B CG 1 ATOM 5937 C CD1 . TYR B 1 333 ? 31.832 -17.012 -15.601 1.00 11.10 ? 333 TYR B CD1 1 ATOM 5938 C CD2 . TYR B 1 333 ? 31.099 -14.741 -15.522 1.00 10.96 ? 333 TYR B CD2 1 ATOM 5939 C CE1 . TYR B 1 333 ? 32.850 -16.654 -16.532 1.00 11.49 ? 333 TYR B CE1 1 ATOM 5940 C CE2 . TYR B 1 333 ? 32.072 -14.368 -16.434 1.00 10.54 ? 333 TYR B CE2 1 ATOM 5941 C CZ . TYR B 1 333 ? 32.949 -15.336 -16.943 1.00 13.35 ? 333 TYR B CZ 1 ATOM 5942 O OH . TYR B 1 333 ? 33.902 -14.954 -17.865 1.00 12.77 ? 333 TYR B OH 1 ATOM 5943 N N . ALA B 1 334 ? 27.683 -18.717 -13.257 1.00 14.10 ? 334 ALA B N 1 ATOM 5944 C CA . ALA B 1 334 ? 26.953 -19.260 -12.157 1.00 14.28 ? 334 ALA B CA 1 ATOM 5945 C C . ALA B 1 334 ? 27.843 -20.316 -11.492 1.00 15.40 ? 334 ALA B C 1 ATOM 5946 O O . ALA B 1 334 ? 28.469 -21.199 -12.179 1.00 14.35 ? 334 ALA B O 1 ATOM 5947 C CB . ALA B 1 334 ? 25.630 -19.827 -12.615 1.00 13.53 ? 334 ALA B CB 1 ATOM 5948 N N . ASP B 1 335 ? 27.916 -20.187 -10.153 1.00 15.96 ? 335 ASP B N 1 ATOM 5949 C CA . ASP B 1 335 ? 28.637 -21.125 -9.303 1.00 15.70 ? 335 ASP B CA 1 ATOM 5950 C C . ASP B 1 335 ? 27.758 -21.674 -8.197 1.00 16.13 ? 335 ASP B C 1 ATOM 5951 O O . ASP B 1 335 ? 26.900 -20.968 -7.660 1.00 16.95 ? 335 ASP B O 1 ATOM 5952 C CB . ASP B 1 335 ? 29.872 -20.459 -8.743 1.00 15.96 ? 335 ASP B CB 1 ATOM 5953 C CG . ASP B 1 335 ? 30.911 -20.153 -9.801 1.00 17.31 ? 335 ASP B CG 1 ATOM 5954 O OD1 . ASP B 1 335 ? 31.219 -21.055 -10.620 1.00 15.87 ? 335 ASP B OD1 1 ATOM 5955 O OD2 . ASP B 1 335 ? 31.428 -18.993 -9.802 1.00 18.07 ? 335 ASP B OD2 1 ATOM 5956 N N . PHE B 1 336 ? 27.972 -22.944 -7.858 1.00 16.28 ? 336 PHE B N 1 ATOM 5957 C CA . PHE B 1 336 ? 27.146 -23.645 -6.872 1.00 16.02 ? 336 PHE B CA 1 ATOM 5958 C C . PHE B 1 336 ? 28.008 -24.378 -5.853 1.00 16.50 ? 336 PHE B C 1 ATOM 5959 O O . PHE B 1 336 ? 28.888 -25.134 -6.239 1.00 17.69 ? 336 PHE B O 1 ATOM 5960 C CB . PHE B 1 336 ? 26.227 -24.656 -7.592 1.00 16.58 ? 336 PHE B CB 1 ATOM 5961 C CG . PHE B 1 336 ? 25.192 -24.006 -8.454 1.00 15.25 ? 336 PHE B CG 1 ATOM 5962 C CD1 . PHE B 1 336 ? 25.502 -23.628 -9.748 1.00 11.31 ? 336 PHE B CD1 1 ATOM 5963 C CD2 . PHE B 1 336 ? 23.898 -23.744 -7.937 1.00 14.36 ? 336 PHE B CD2 1 ATOM 5964 C CE1 . PHE B 1 336 ? 24.574 -23.010 -10.530 1.00 13.08 ? 336 PHE B CE1 1 ATOM 5965 C CE2 . PHE B 1 336 ? 22.950 -23.106 -8.713 1.00 12.32 ? 336 PHE B CE2 1 ATOM 5966 C CZ . PHE B 1 336 ? 23.295 -22.735 -10.021 1.00 15.48 ? 336 PHE B CZ 1 ATOM 5967 N N . SER B 1 337 ? 27.741 -24.198 -4.560 1.00 16.52 ? 337 SER B N 1 ATOM 5968 C CA . SER B 1 337 ? 28.674 -24.639 -3.523 1.00 15.82 ? 337 SER B CA 1 ATOM 5969 C C . SER B 1 337 ? 27.934 -24.832 -2.209 1.00 16.00 ? 337 SER B C 1 ATOM 5970 O O . SER B 1 337 ? 26.690 -24.854 -2.220 1.00 18.09 ? 337 SER B O 1 ATOM 5971 C CB . SER B 1 337 ? 29.768 -23.602 -3.361 1.00 15.36 ? 337 SER B CB 1 ATOM 5972 O OG . SER B 1 337 ? 30.851 -24.143 -2.634 1.00 17.87 ? 337 SER B OG 1 ATOM 5973 N N . HIS B 1 338 ? 28.666 -24.968 -1.092 1.00 15.59 ? 338 HIS B N 1 ATOM 5974 C CA . HIS B 1 338 ? 28.091 -25.081 0.267 1.00 14.33 ? 338 HIS B CA 1 ATOM 5975 C C . HIS B 1 338 ? 28.152 -23.807 1.048 1.00 14.65 ? 338 HIS B C 1 ATOM 5976 O O . HIS B 1 338 ? 28.976 -22.923 0.756 1.00 14.03 ? 338 HIS B O 1 ATOM 5977 C CB . HIS B 1 338 ? 28.849 -26.108 1.120 1.00 14.21 ? 338 HIS B CB 1 ATOM 5978 C CG . HIS B 1 338 ? 29.037 -27.433 0.463 1.00 12.59 ? 338 HIS B CG 1 ATOM 5979 N ND1 . HIS B 1 338 ? 28.187 -28.490 0.681 1.00 10.96 ? 338 HIS B ND1 1 ATOM 5980 C CD2 . HIS B 1 338 ? 29.990 -27.879 -0.388 1.00 13.98 ? 338 HIS B CD2 1 ATOM 5981 C CE1 . HIS B 1 338 ? 28.592 -29.530 -0.022 1.00 14.89 ? 338 HIS B CE1 1 ATOM 5982 N NE2 . HIS B 1 338 ? 29.692 -29.192 -0.674 1.00 16.12 ? 338 HIS B NE2 1 ATOM 5983 N N . ASP B 1 339 ? 27.334 -23.760 2.102 1.00 14.90 ? 339 ASP B N 1 ATOM 5984 C CA . ASP B 1 339 ? 27.337 -22.670 3.068 1.00 15.85 ? 339 ASP B CA 1 ATOM 5985 C C . ASP B 1 339 ? 28.737 -22.284 3.545 1.00 16.18 ? 339 ASP B C 1 ATOM 5986 O O . ASP B 1 339 ? 29.132 -21.103 3.500 1.00 17.29 ? 339 ASP B O 1 ATOM 5987 C CB . ASP B 1 339 ? 26.424 -22.967 4.286 1.00 15.17 ? 339 ASP B CB 1 ATOM 5988 C CG . ASP B 1 339 ? 26.789 -24.247 5.022 1.00 16.04 ? 339 ASP B CG 1 ATOM 5989 O OD1 . ASP B 1 339 ? 27.829 -24.887 4.738 1.00 15.73 ? 339 ASP B OD1 1 ATOM 5990 O OD2 . ASP B 1 339 ? 26.014 -24.656 5.901 1.00 17.89 ? 339 ASP B OD2 1 ATOM 5991 N N . ASN B 1 340 ? 29.494 -23.274 3.977 1.00 16.17 ? 340 ASN B N 1 ATOM 5992 C CA . ASN B 1 340 ? 30.766 -22.975 4.625 1.00 17.26 ? 340 ASN B CA 1 ATOM 5993 C C . ASN B 1 340 ? 31.695 -22.235 3.690 1.00 16.89 ? 340 ASN B C 1 ATOM 5994 O O . ASN B 1 340 ? 32.314 -21.255 4.097 1.00 16.57 ? 340 ASN B O 1 ATOM 5995 C CB . ASN B 1 340 ? 31.429 -24.246 5.209 1.00 16.59 ? 340 ASN B CB 1 ATOM 5996 C CG . ASN B 1 340 ? 30.618 -24.843 6.378 1.00 17.64 ? 340 ASN B CG 1 ATOM 5997 O OD1 . ASN B 1 340 ? 29.852 -24.123 7.074 1.00 15.02 ? 340 ASN B OD1 1 ATOM 5998 N ND2 . ASN B 1 340 ? 30.788 -26.152 6.607 1.00 15.54 ? 340 ASN B ND2 1 ATOM 5999 N N . GLY B 1 341 ? 31.782 -22.686 2.441 1.00 16.16 ? 341 GLY B N 1 ATOM 6000 C CA . GLY B 1 341 ? 32.703 -22.045 1.498 1.00 16.33 ? 341 GLY B CA 1 ATOM 6001 C C . GLY B 1 341 ? 32.195 -20.667 1.126 1.00 16.64 ? 341 GLY B C 1 ATOM 6002 O O . GLY B 1 341 ? 32.966 -19.790 0.755 1.00 16.79 ? 341 GLY B O 1 ATOM 6003 N N . ILE B 1 342 ? 30.885 -20.470 1.238 1.00 16.70 ? 342 ILE B N 1 ATOM 6004 C CA . ILE B 1 342 ? 30.250 -19.224 0.805 1.00 16.64 ? 342 ILE B CA 1 ATOM 6005 C C . ILE B 1 342 ? 30.484 -18.183 1.884 1.00 17.33 ? 342 ILE B C 1 ATOM 6006 O O . ILE B 1 342 ? 30.668 -17.010 1.575 1.00 17.74 ? 342 ILE B O 1 ATOM 6007 C CB . ILE B 1 342 ? 28.703 -19.416 0.528 1.00 17.07 ? 342 ILE B CB 1 ATOM 6008 C CG1 . ILE B 1 342 ? 28.484 -20.183 -0.776 1.00 15.39 ? 342 ILE B CG1 1 ATOM 6009 C CG2 . ILE B 1 342 ? 28.013 -18.121 0.399 1.00 14.33 ? 342 ILE B CG2 1 ATOM 6010 C CD1 . ILE B 1 342 ? 27.090 -20.743 -0.901 1.00 17.21 ? 342 ILE B CD1 1 ATOM 6011 N N . ILE B 1 343 ? 30.467 -18.620 3.154 1.00 17.17 ? 343 ILE B N 1 ATOM 6012 C CA . ILE B 1 343 ? 30.805 -17.745 4.265 1.00 15.78 ? 343 ILE B CA 1 ATOM 6013 C C . ILE B 1 343 ? 32.208 -17.219 4.002 1.00 15.42 ? 343 ILE B C 1 ATOM 6014 O O . ILE B 1 343 ? 32.394 -16.006 3.903 1.00 16.15 ? 343 ILE B O 1 ATOM 6015 C CB . ILE B 1 343 ? 30.731 -18.475 5.639 1.00 15.69 ? 343 ILE B CB 1 ATOM 6016 C CG1 . ILE B 1 343 ? 29.294 -18.815 6.019 1.00 14.36 ? 343 ILE B CG1 1 ATOM 6017 C CG2 . ILE B 1 343 ? 31.386 -17.648 6.719 1.00 16.01 ? 343 ILE B CG2 1 ATOM 6018 C CD1 . ILE B 1 343 ? 28.423 -17.623 6.376 1.00 7.87 ? 343 ILE B CD1 1 ATOM 6019 N N . SER B 1 344 ? 33.180 -18.122 3.851 1.00 14.78 ? 344 SER B N 1 ATOM 6020 C CA . SER B 1 344 ? 34.585 -17.755 3.636 1.00 14.96 ? 344 SER B CA 1 ATOM 6021 C C . SER B 1 344 ? 34.730 -16.769 2.495 1.00 15.58 ? 344 SER B C 1 ATOM 6022 O O . SER B 1 344 ? 35.490 -15.768 2.609 1.00 16.41 ? 344 SER B O 1 ATOM 6023 C CB . SER B 1 344 ? 35.480 -18.980 3.376 1.00 14.17 ? 344 SER B CB 1 ATOM 6024 O OG . SER B 1 344 ? 35.433 -19.877 4.472 1.00 15.28 ? 344 SER B OG 1 ATOM 6025 N N . ILE B 1 345 ? 33.983 -17.026 1.417 1.00 15.17 ? 345 ILE B N 1 ATOM 6026 C CA . ILE B 1 345 ? 34.028 -16.161 0.230 1.00 15.45 ? 345 ILE B CA 1 ATOM 6027 C C . ILE B 1 345 ? 33.508 -14.724 0.475 1.00 14.75 ? 345 ILE B C 1 ATOM 6028 O O . ILE B 1 345 ? 34.158 -13.738 0.090 1.00 13.75 ? 345 ILE B O 1 ATOM 6029 C CB . ILE B 1 345 ? 33.317 -16.834 -0.987 1.00 15.40 ? 345 ILE B CB 1 ATOM 6030 C CG1 . ILE B 1 345 ? 34.102 -18.072 -1.436 1.00 14.40 ? 345 ILE B CG1 1 ATOM 6031 C CG2 . ILE B 1 345 ? 33.151 -15.820 -2.129 1.00 14.05 ? 345 ILE B CG2 1 ATOM 6032 C CD1 . ILE B 1 345 ? 33.391 -18.884 -2.532 1.00 14.53 ? 345 ILE B CD1 1 ATOM 6033 N N . LEU B 1 346 ? 32.327 -14.631 1.087 1.00 14.96 ? 346 LEU B N 1 ATOM 6034 C CA . LEU B 1 346 ? 31.743 -13.370 1.501 1.00 15.34 ? 346 LEU B CA 1 ATOM 6035 C C . LEU B 1 346 ? 32.740 -12.489 2.311 1.00 16.28 ? 346 LEU B C 1 ATOM 6036 O O . LEU B 1 346 ? 32.978 -11.300 1.961 1.00 17.08 ? 346 LEU B O 1 ATOM 6037 C CB . LEU B 1 346 ? 30.476 -13.627 2.313 1.00 15.79 ? 346 LEU B CB 1 ATOM 6038 C CG . LEU B 1 346 ? 29.293 -14.314 1.652 1.00 15.91 ? 346 LEU B CG 1 ATOM 6039 C CD1 . LEU B 1 346 ? 28.080 -14.348 2.592 1.00 17.49 ? 346 LEU B CD1 1 ATOM 6040 C CD2 . LEU B 1 346 ? 28.954 -13.599 0.396 1.00 16.44 ? 346 LEU B CD2 1 ATOM 6041 N N . PHE B 1 347 ? 33.335 -13.060 3.364 1.00 15.70 ? 347 PHE B N 1 ATOM 6042 C CA . PHE B 1 347 ? 34.354 -12.354 4.167 1.00 15.89 ? 347 PHE B CA 1 ATOM 6043 C C . PHE B 1 347 ? 35.653 -12.010 3.412 1.00 16.10 ? 347 PHE B C 1 ATOM 6044 O O . PHE B 1 347 ? 36.162 -10.919 3.595 1.00 17.29 ? 347 PHE B O 1 ATOM 6045 C CB . PHE B 1 347 ? 34.674 -13.111 5.467 1.00 15.07 ? 347 PHE B CB 1 ATOM 6046 C CG . PHE B 1 347 ? 33.638 -12.942 6.524 1.00 14.38 ? 347 PHE B CG 1 ATOM 6047 C CD1 . PHE B 1 347 ? 33.715 -11.877 7.423 1.00 11.77 ? 347 PHE B CD1 1 ATOM 6048 C CD2 . PHE B 1 347 ? 32.578 -13.855 6.647 1.00 10.18 ? 347 PHE B CD2 1 ATOM 6049 C CE1 . PHE B 1 347 ? 32.701 -11.712 8.424 1.00 11.84 ? 347 PHE B CE1 1 ATOM 6050 C CE2 . PHE B 1 347 ? 31.583 -13.698 7.643 1.00 10.93 ? 347 PHE B CE2 1 ATOM 6051 C CZ . PHE B 1 347 ? 31.652 -12.640 8.518 1.00 10.08 ? 347 PHE B CZ 1 ATOM 6052 N N . ALA B 1 348 ? 36.182 -12.893 2.570 1.00 16.10 ? 348 ALA B N 1 ATOM 6053 C CA . ALA B 1 348 ? 37.394 -12.540 1.766 1.00 16.27 ? 348 ALA B CA 1 ATOM 6054 C C . ALA B 1 348 ? 37.129 -11.409 0.757 1.00 16.50 ? 348 ALA B C 1 ATOM 6055 O O . ALA B 1 348 ? 38.064 -10.719 0.286 1.00 16.39 ? 348 ALA B O 1 ATOM 6056 C CB . ALA B 1 348 ? 37.925 -13.726 1.053 1.00 15.79 ? 348 ALA B CB 1 ATOM 6057 N N . LEU B 1 349 ? 35.863 -11.208 0.418 1.00 15.96 ? 349 LEU B N 1 ATOM 6058 C CA . LEU B 1 349 ? 35.527 -10.153 -0.538 1.00 16.06 ? 349 LEU B CA 1 ATOM 6059 C C . LEU B 1 349 ? 35.311 -8.841 0.197 1.00 16.47 ? 349 LEU B C 1 ATOM 6060 O O . LEU B 1 349 ? 34.998 -7.843 -0.425 1.00 16.75 ? 349 LEU B O 1 ATOM 6061 C CB . LEU B 1 349 ? 34.289 -10.507 -1.371 1.00 15.36 ? 349 LEU B CB 1 ATOM 6062 C CG . LEU B 1 349 ? 34.427 -11.692 -2.337 1.00 16.73 ? 349 LEU B CG 1 ATOM 6063 C CD1 . LEU B 1 349 ? 33.065 -12.154 -2.884 1.00 14.35 ? 349 LEU B CD1 1 ATOM 6064 C CD2 . LEU B 1 349 ? 35.419 -11.364 -3.463 1.00 16.12 ? 349 LEU B CD2 1 ATOM 6065 N N . GLY B 1 350 ? 35.435 -8.883 1.528 1.00 16.78 ? 350 GLY B N 1 ATOM 6066 C CA . GLY B 1 350 ? 35.297 -7.729 2.375 1.00 16.83 ? 350 GLY B CA 1 ATOM 6067 C C . GLY B 1 350 ? 33.879 -7.371 2.746 1.00 17.58 ? 350 GLY B C 1 ATOM 6068 O O . GLY B 1 350 ? 33.661 -6.412 3.452 1.00 18.27 ? 350 GLY B O 1 ATOM 6069 N N . LEU B 1 351 ? 32.907 -8.132 2.267 1.00 18.40 ? 351 LEU B N 1 ATOM 6070 C CA . LEU B 1 351 ? 31.493 -7.784 2.445 1.00 18.82 ? 351 LEU B CA 1 ATOM 6071 C C . LEU B 1 351 ? 31.069 -7.585 3.863 1.00 19.00 ? 351 LEU B C 1 ATOM 6072 O O . LEU B 1 351 ? 30.019 -6.993 4.121 1.00 20.80 ? 351 LEU B O 1 ATOM 6073 C CB . LEU B 1 351 ? 30.581 -8.810 1.768 1.00 19.05 ? 351 LEU B CB 1 ATOM 6074 C CG . LEU B 1 351 ? 30.959 -9.060 0.295 1.00 21.24 ? 351 LEU B CG 1 ATOM 6075 C CD1 . LEU B 1 351 ? 30.045 -10.094 -0.299 1.00 19.99 ? 351 LEU B CD1 1 ATOM 6076 C CD2 . LEU B 1 351 ? 30.943 -7.729 -0.507 1.00 20.51 ? 351 LEU B CD2 1 ATOM 6077 N N . TYR B 1 352 ? 31.850 -8.065 4.813 1.00 18.81 ? 352 TYR B N 1 ATOM 6078 C CA . TYR B 1 352 ? 31.435 -7.887 6.202 1.00 18.90 ? 352 TYR B CA 1 ATOM 6079 C C . TYR B 1 352 ? 32.461 -7.131 7.076 1.00 19.59 ? 352 TYR B C 1 ATOM 6080 O O . TYR B 1 352 ? 32.587 -7.348 8.284 1.00 19.36 ? 352 TYR B O 1 ATOM 6081 C CB . TYR B 1 352 ? 30.872 -9.189 6.775 1.00 17.91 ? 352 TYR B CB 1 ATOM 6082 C CG . TYR B 1 352 ? 29.540 -9.515 6.099 1.00 17.28 ? 352 TYR B CG 1 ATOM 6083 C CD1 . TYR B 1 352 ? 28.323 -8.909 6.534 1.00 15.28 ? 352 TYR B CD1 1 ATOM 6084 C CD2 . TYR B 1 352 ? 29.498 -10.405 5.006 1.00 12.53 ? 352 TYR B CD2 1 ATOM 6085 C CE1 . TYR B 1 352 ? 27.096 -9.186 5.874 1.00 13.40 ? 352 TYR B CE1 1 ATOM 6086 C CE2 . TYR B 1 352 ? 28.330 -10.687 4.350 1.00 13.88 ? 352 TYR B CE2 1 ATOM 6087 C CZ . TYR B 1 352 ? 27.119 -10.101 4.772 1.00 15.51 ? 352 TYR B CZ 1 ATOM 6088 O OH . TYR B 1 352 ? 25.982 -10.440 4.070 1.00 16.66 ? 352 TYR B OH 1 ATOM 6089 N N . ASN B 1 353 ? 33.128 -6.174 6.439 1.00 19.93 ? 353 ASN B N 1 ATOM 6090 C CA . ASN B 1 353 ? 34.213 -5.452 7.083 1.00 21.67 ? 353 ASN B CA 1 ATOM 6091 C C . ASN B 1 353 ? 33.751 -4.219 7.878 1.00 22.45 ? 353 ASN B C 1 ATOM 6092 O O . ASN B 1 353 ? 34.559 -3.363 8.230 1.00 22.39 ? 353 ASN B O 1 ATOM 6093 C CB . ASN B 1 353 ? 35.297 -5.091 6.061 1.00 21.43 ? 353 ASN B CB 1 ATOM 6094 C CG . ASN B 1 353 ? 36.366 -6.106 6.005 1.00 21.58 ? 353 ASN B CG 1 ATOM 6095 O OD1 . ASN B 1 353 ? 36.158 -7.268 6.393 1.00 20.94 ? 353 ASN B OD1 1 ATOM 6096 N ND2 . ASN B 1 353 ? 37.538 -5.692 5.549 1.00 20.62 ? 353 ASN B ND2 1 ATOM 6097 N N . GLY B 1 354 ? 32.451 -4.138 8.157 1.00 23.53 ? 354 GLY B N 1 ATOM 6098 C CA . GLY B 1 354 ? 31.921 -3.147 9.116 1.00 24.39 ? 354 GLY B CA 1 ATOM 6099 C C . GLY B 1 354 ? 31.239 -3.874 10.263 1.00 25.21 ? 354 GLY B C 1 ATOM 6100 O O . GLY B 1 354 ? 30.557 -3.251 11.047 1.00 25.58 ? 354 GLY B O 1 ATOM 6101 N N . THR B 1 355 ? 31.437 -5.199 10.331 1.00 25.73 ? 355 THR B N 1 ATOM 6102 C CA . THR B 1 355 ? 30.863 -6.103 11.342 1.00 25.78 ? 355 THR B CA 1 ATOM 6103 C C . THR B 1 355 ? 31.892 -6.431 12.469 1.00 26.80 ? 355 THR B C 1 ATOM 6104 O O . THR B 1 355 ? 32.995 -6.937 12.197 1.00 26.49 ? 355 THR B O 1 ATOM 6105 C CB . THR B 1 355 ? 30.384 -7.460 10.698 1.00 25.74 ? 355 THR B CB 1 ATOM 6106 O OG1 . THR B 1 355 ? 29.224 -7.258 9.883 1.00 24.01 ? 355 THR B OG1 1 ATOM 6107 C CG2 . THR B 1 355 ? 30.096 -8.551 11.769 1.00 23.96 ? 355 THR B CG2 1 ATOM 6108 N N . LYS B 1 356 ? 31.493 -6.182 13.728 1.00 27.16 ? 356 LYS B N 1 ATOM 6109 C CA . LYS B 1 356 ? 32.324 -6.468 14.897 1.00 27.49 ? 356 LYS B CA 1 ATOM 6110 C C . LYS B 1 356 ? 32.202 -7.918 15.368 1.00 26.90 ? 356 LYS B C 1 ATOM 6111 O O . LYS B 1 356 ? 31.097 -8.423 15.496 1.00 27.97 ? 356 LYS B O 1 ATOM 6112 C CB . LYS B 1 356 ? 32.024 -5.477 16.018 1.00 27.50 ? 356 LYS B CB 1 ATOM 6113 C CG . LYS B 1 356 ? 33.057 -4.349 16.043 1.00 30.72 ? 356 LYS B CG 1 ATOM 6114 C CD . LYS B 1 356 ? 32.445 -2.948 16.139 1.00 36.19 ? 356 LYS B CD 1 ATOM 6115 C CE . LYS B 1 356 ? 33.526 -1.884 15.752 1.00 42.36 ? 356 LYS B CE 1 ATOM 6116 N NZ . LYS B 1 356 ? 33.213 -0.393 15.939 1.00 44.84 ? 356 LYS B NZ 1 ATOM 6117 N N . PRO B 1 357 ? 33.338 -8.577 15.657 1.00 26.14 ? 357 PRO B N 1 ATOM 6118 C CA . PRO B 1 357 ? 33.356 -9.982 16.037 1.00 25.99 ? 357 PRO B CA 1 ATOM 6119 C C . PRO B 1 357 ? 32.226 -10.262 16.996 1.00 26.02 ? 357 PRO B C 1 ATOM 6120 O O . PRO B 1 357 ? 32.016 -9.505 17.941 1.00 26.57 ? 357 PRO B O 1 ATOM 6121 C CB . PRO B 1 357 ? 34.697 -10.128 16.751 1.00 26.45 ? 357 PRO B CB 1 ATOM 6122 C CG . PRO B 1 357 ? 35.556 -9.090 16.136 1.00 26.47 ? 357 PRO B CG 1 ATOM 6123 C CD . PRO B 1 357 ? 34.646 -7.930 15.858 1.00 26.11 ? 357 PRO B CD 1 ATOM 6124 N N . LEU B 1 358 ? 31.475 -11.318 16.755 1.00 25.48 ? 358 LEU B N 1 ATOM 6125 C CA . LEU B 1 358 ? 30.244 -11.476 17.475 1.00 25.80 ? 358 LEU B CA 1 ATOM 6126 C C . LEU B 1 358 ? 30.584 -11.882 18.881 1.00 27.69 ? 358 LEU B C 1 ATOM 6127 O O . LEU B 1 358 ? 31.557 -12.663 19.092 1.00 27.44 ? 358 LEU B O 1 ATOM 6128 C CB . LEU B 1 358 ? 29.340 -12.535 16.834 1.00 24.66 ? 358 LEU B CB 1 ATOM 6129 C CG . LEU B 1 358 ? 29.081 -12.538 15.326 1.00 24.86 ? 358 LEU B CG 1 ATOM 6130 C CD1 . LEU B 1 358 ? 27.955 -13.513 14.977 1.00 22.22 ? 358 LEU B CD1 1 ATOM 6131 C CD2 . LEU B 1 358 ? 28.816 -11.166 14.742 1.00 20.27 ? 358 LEU B CD2 1 ATOM 6132 N N . SER B 1 359 ? 29.779 -11.379 19.835 1.00 28.66 ? 359 SER B N 1 ATOM 6133 C CA . SER B 1 359 ? 29.939 -11.712 21.256 1.00 29.44 ? 359 SER B CA 1 ATOM 6134 C C . SER B 1 359 ? 29.763 -13.194 21.441 1.00 29.87 ? 359 SER B C 1 ATOM 6135 O O . SER B 1 359 ? 28.835 -13.775 20.875 1.00 30.35 ? 359 SER B O 1 ATOM 6136 C CB . SER B 1 359 ? 28.901 -10.978 22.121 1.00 29.84 ? 359 SER B CB 1 ATOM 6137 O OG . SER B 1 359 ? 28.632 -11.720 23.310 1.00 29.46 ? 359 SER B OG 1 ATOM 6138 N N . THR B 1 360 ? 30.628 -13.811 22.236 1.00 30.37 ? 360 THR B N 1 ATOM 6139 C CA . THR B 1 360 ? 30.484 -15.251 22.504 1.00 31.33 ? 360 THR B CA 1 ATOM 6140 C C . THR B 1 360 ? 29.437 -15.591 23.603 1.00 31.76 ? 360 THR B C 1 ATOM 6141 O O . THR B 1 360 ? 29.084 -16.736 23.798 1.00 31.21 ? 360 THR B O 1 ATOM 6142 C CB . THR B 1 360 ? 31.873 -15.929 22.778 1.00 31.45 ? 360 THR B CB 1 ATOM 6143 O OG1 . THR B 1 360 ? 32.497 -15.301 23.902 1.00 30.30 ? 360 THR B OG1 1 ATOM 6144 C CG2 . THR B 1 360 ? 32.806 -15.810 21.554 1.00 30.82 ? 360 THR B CG2 1 ATOM 6145 N N . THR B 1 361 ? 28.909 -14.567 24.268 1.00 33.62 ? 361 THR B N 1 ATOM 6146 C CA . THR B 1 361 ? 28.121 -14.707 25.520 1.00 34.64 ? 361 THR B CA 1 ATOM 6147 C C . THR B 1 361 ? 26.670 -14.167 25.428 1.00 35.24 ? 361 THR B C 1 ATOM 6148 O O . THR B 1 361 ? 25.751 -14.680 26.076 1.00 34.98 ? 361 THR B O 1 ATOM 6149 C CB . THR B 1 361 ? 28.820 -13.919 26.664 1.00 34.79 ? 361 THR B CB 1 ATOM 6150 O OG1 . THR B 1 361 ? 28.716 -12.516 26.382 1.00 34.56 ? 361 THR B OG1 1 ATOM 6151 C CG2 . THR B 1 361 ? 30.322 -14.296 26.809 1.00 34.31 ? 361 THR B CG2 1 ATOM 6152 N N . THR B 1 362 ? 26.482 -13.104 24.641 1.00 36.45 ? 362 THR B N 1 ATOM 6153 C CA . THR B 1 362 ? 25.168 -12.470 24.446 1.00 37.05 ? 362 THR B CA 1 ATOM 6154 C C . THR B 1 362 ? 24.730 -12.430 22.965 1.00 36.59 ? 362 THR B C 1 ATOM 6155 O O . THR B 1 362 ? 25.545 -12.147 22.092 1.00 36.48 ? 362 THR B O 1 ATOM 6156 C CB . THR B 1 362 ? 25.187 -10.974 24.901 1.00 37.81 ? 362 THR B CB 1 ATOM 6157 O OG1 . THR B 1 362 ? 26.479 -10.615 25.437 1.00 39.48 ? 362 THR B OG1 1 ATOM 6158 C CG2 . THR B 1 362 ? 24.042 -10.682 25.910 1.00 38.34 ? 362 THR B CG2 1 ATOM 6159 N N . VAL B 1 363 ? 23.439 -12.669 22.714 1.00 35.93 ? 363 VAL B N 1 ATOM 6160 C CA . VAL B 1 363 ? 22.767 -12.329 21.453 1.00 35.76 ? 363 VAL B CA 1 ATOM 6161 C C . VAL B 1 363 ? 23.048 -10.896 20.916 1.00 35.44 ? 363 VAL B C 1 ATOM 6162 O O . VAL B 1 363 ? 22.898 -9.899 21.650 1.00 34.79 ? 363 VAL B O 1 ATOM 6163 C CB . VAL B 1 363 ? 21.227 -12.430 21.609 1.00 36.04 ? 363 VAL B CB 1 ATOM 6164 C CG1 . VAL B 1 363 ? 20.534 -12.078 20.300 1.00 36.80 ? 363 VAL B CG1 1 ATOM 6165 C CG2 . VAL B 1 363 ? 20.811 -13.808 22.102 1.00 35.81 ? 363 VAL B CG2 1 ATOM 6166 N N . GLU B 1 364 ? 23.445 -10.817 19.638 1.00 34.50 ? 364 GLU B N 1 ATOM 6167 C CA . GLU B 1 364 ? 23.539 -9.547 18.908 1.00 34.14 ? 364 GLU B CA 1 ATOM 6168 C C . GLU B 1 364 ? 22.546 -9.543 17.746 1.00 33.66 ? 364 GLU B C 1 ATOM 6169 O O . GLU B 1 364 ? 22.604 -10.438 16.893 1.00 34.38 ? 364 GLU B O 1 ATOM 6170 C CB . GLU B 1 364 ? 24.967 -9.303 18.405 1.00 33.26 ? 364 GLU B CB 1 ATOM 6171 C CG . GLU B 1 364 ? 25.966 -9.228 19.536 1.00 34.25 ? 364 GLU B CG 1 ATOM 6172 C CD . GLU B 1 364 ? 27.396 -8.846 19.123 1.00 35.32 ? 364 GLU B CD 1 ATOM 6173 O OE1 . GLU B 1 364 ? 28.069 -8.166 19.923 1.00 38.80 ? 364 GLU B OE1 1 ATOM 6174 O OE2 . GLU B 1 364 ? 27.870 -9.213 18.037 1.00 33.30 ? 364 GLU B OE2 1 ATOM 6175 N N . ASN B 1 365 ? 21.649 -8.550 17.717 1.00 32.64 ? 365 ASN B N 1 ATOM 6176 C CA . ASN B 1 365 ? 20.664 -8.399 16.639 1.00 31.70 ? 365 ASN B CA 1 ATOM 6177 C C . ASN B 1 365 ? 21.290 -8.006 15.298 1.00 31.63 ? 365 ASN B C 1 ATOM 6178 O O . ASN B 1 365 ? 22.499 -7.740 15.215 1.00 31.26 ? 365 ASN B O 1 ATOM 6179 C CB . ASN B 1 365 ? 19.531 -7.438 17.039 1.00 31.31 ? 365 ASN B CB 1 ATOM 6180 C CG . ASN B 1 365 ? 20.004 -6.008 17.269 1.00 31.84 ? 365 ASN B CG 1 ATOM 6181 O OD1 . ASN B 1 365 ? 20.630 -5.389 16.405 1.00 33.23 ? 365 ASN B OD1 1 ATOM 6182 N ND2 . ASN B 1 365 ? 19.665 -5.459 18.426 1.00 32.06 ? 365 ASN B ND2 1 ATOM 6183 N N . ILE B 1 366 ? 20.465 -7.951 14.249 1.00 31.56 ? 366 ILE B N 1 ATOM 6184 C CA . ILE B 1 366 ? 20.996 -7.765 12.898 1.00 30.81 ? 366 ILE B CA 1 ATOM 6185 C C . ILE B 1 366 ? 21.626 -6.374 12.675 1.00 30.94 ? 366 ILE B C 1 ATOM 6186 O O . ILE B 1 366 ? 22.438 -6.215 11.761 1.00 30.83 ? 366 ILE B O 1 ATOM 6187 C CB . ILE B 1 366 ? 19.962 -8.162 11.776 1.00 30.76 ? 366 ILE B CB 1 ATOM 6188 C CG1 . ILE B 1 366 ? 20.663 -8.343 10.425 1.00 29.97 ? 366 ILE B CG1 1 ATOM 6189 C CG2 . ILE B 1 366 ? 18.852 -7.129 11.647 1.00 28.35 ? 366 ILE B CG2 1 ATOM 6190 C CD1 . ILE B 1 366 ? 21.583 -9.558 10.339 1.00 28.55 ? 366 ILE B CD1 1 ATOM 6191 N N . THR B 1 367 ? 21.280 -5.395 13.524 1.00 30.87 ? 367 THR B N 1 ATOM 6192 C CA . THR B 1 367 ? 21.945 -4.069 13.529 1.00 30.75 ? 367 THR B CA 1 ATOM 6193 C C . THR B 1 367 ? 23.330 -4.150 14.143 1.00 30.65 ? 367 THR B C 1 ATOM 6194 O O . THR B 1 367 ? 24.327 -3.740 13.543 1.00 31.07 ? 367 THR B O 1 ATOM 6195 C CB . THR B 1 367 ? 21.165 -3.042 14.350 1.00 31.06 ? 367 THR B CB 1 ATOM 6196 O OG1 . THR B 1 367 ? 19.779 -3.122 14.022 1.00 31.62 ? 367 THR B OG1 1 ATOM 6197 C CG2 . THR B 1 367 ? 21.673 -1.605 14.080 1.00 32.26 ? 367 THR B CG2 1 ATOM 6198 N N . GLN B 1 368 ? 23.399 -4.690 15.352 1.00 30.49 ? 368 GLN B N 1 ATOM 6199 C CA . GLN B 1 368 ? 24.681 -4.856 16.027 1.00 29.77 ? 368 GLN B CA 1 ATOM 6200 C C . GLN B 1 368 ? 25.687 -5.594 15.126 1.00 28.92 ? 368 GLN B C 1 ATOM 6201 O O . GLN B 1 368 ? 26.840 -5.173 15.022 1.00 29.02 ? 368 GLN B O 1 ATOM 6202 C CB . GLN B 1 368 ? 24.489 -5.555 17.364 1.00 29.94 ? 368 GLN B CB 1 ATOM 6203 C CG . GLN B 1 368 ? 23.329 -4.957 18.185 1.00 31.36 ? 368 GLN B CG 1 ATOM 6204 C CD . GLN B 1 368 ? 23.110 -5.676 19.485 1.00 32.24 ? 368 GLN B CD 1 ATOM 6205 O OE1 . GLN B 1 368 ? 22.199 -6.504 19.617 1.00 30.56 ? 368 GLN B OE1 1 ATOM 6206 N NE2 . GLN B 1 368 ? 23.973 -5.388 20.463 1.00 34.19 ? 368 GLN B NE2 1 ATOM 6207 N N . THR B 1 369 ? 25.257 -6.646 14.437 1.00 27.45 ? 369 THR B N 1 ATOM 6208 C CA . THR B 1 369 ? 26.192 -7.356 13.530 1.00 26.79 ? 369 THR B CA 1 ATOM 6209 C C . THR B 1 369 ? 26.362 -6.714 12.125 1.00 26.22 ? 369 THR B C 1 ATOM 6210 O O . THR B 1 369 ? 26.983 -7.327 11.232 1.00 25.82 ? 369 THR B O 1 ATOM 6211 C CB . THR B 1 369 ? 25.840 -8.856 13.365 1.00 26.15 ? 369 THR B CB 1 ATOM 6212 O OG1 . THR B 1 369 ? 24.588 -8.948 12.692 1.00 27.13 ? 369 THR B OG1 1 ATOM 6213 C CG2 . THR B 1 369 ? 25.739 -9.541 14.681 1.00 24.38 ? 369 THR B CG2 1 ATOM 6214 N N . ASP B 1 370 ? 25.801 -5.500 11.935 1.00 26.44 ? 370 ASP B N 1 ATOM 6215 C CA . ASP B 1 370 ? 25.851 -4.754 10.654 1.00 25.13 ? 370 ASP B CA 1 ATOM 6216 C C . ASP B 1 370 ? 25.438 -5.669 9.477 1.00 24.20 ? 370 ASP B C 1 ATOM 6217 O O . ASP B 1 370 ? 26.121 -5.751 8.467 1.00 24.01 ? 370 ASP B O 1 ATOM 6218 C CB . ASP B 1 370 ? 27.253 -4.142 10.443 1.00 25.14 ? 370 ASP B CB 1 ATOM 6219 C CG . ASP B 1 370 ? 27.310 -3.137 9.288 1.00 27.59 ? 370 ASP B CG 1 ATOM 6220 O OD1 . ASP B 1 370 ? 26.320 -2.410 9.092 1.00 30.11 ? 370 ASP B OD1 1 ATOM 6221 O OD2 . ASP B 1 370 ? 28.360 -3.053 8.595 1.00 28.54 ? 370 ASP B OD2 1 ATOM 6222 N N . GLY B 1 371 ? 24.327 -6.379 9.638 1.00 22.87 ? 371 GLY B N 1 ATOM 6223 C CA . GLY B 1 371 ? 23.800 -7.223 8.567 1.00 21.91 ? 371 GLY B CA 1 ATOM 6224 C C . GLY B 1 371 ? 24.319 -8.646 8.422 1.00 20.75 ? 371 GLY B C 1 ATOM 6225 O O . GLY B 1 371 ? 23.930 -9.317 7.499 1.00 21.10 ? 371 GLY B O 1 ATOM 6226 N N . PHE B 1 372 ? 25.181 -9.115 9.317 1.00 20.13 ? 372 PHE B N 1 ATOM 6227 C CA . PHE B 1 372 ? 25.639 -10.507 9.245 1.00 19.02 ? 372 PHE B CA 1 ATOM 6228 C C . PHE B 1 372 ? 24.856 -11.490 10.076 1.00 18.64 ? 372 PHE B C 1 ATOM 6229 O O . PHE B 1 372 ? 24.641 -11.273 11.255 1.00 18.65 ? 372 PHE B O 1 ATOM 6230 C CB . PHE B 1 372 ? 27.112 -10.706 9.617 1.00 19.11 ? 372 PHE B CB 1 ATOM 6231 C CG . PHE B 1 372 ? 27.495 -12.152 9.598 1.00 18.18 ? 372 PHE B CG 1 ATOM 6232 C CD1 . PHE B 1 372 ? 27.756 -12.793 8.392 1.00 18.48 ? 372 PHE B CD1 1 ATOM 6233 C CD2 . PHE B 1 372 ? 27.451 -12.917 10.763 1.00 18.43 ? 372 PHE B CD2 1 ATOM 6234 C CE1 . PHE B 1 372 ? 28.021 -14.167 8.341 1.00 17.96 ? 372 PHE B CE1 1 ATOM 6235 C CE2 . PHE B 1 372 ? 27.719 -14.267 10.725 1.00 17.32 ? 372 PHE B CE2 1 ATOM 6236 C CZ . PHE B 1 372 ? 28.015 -14.898 9.517 1.00 17.57 ? 372 PHE B CZ 1 ATOM 6237 N N . SER B 1 373 ? 24.471 -12.601 9.465 1.00 17.93 ? 373 SER B N 1 ATOM 6238 C CA . SER B 1 373 ? 23.883 -13.703 10.205 1.00 17.88 ? 373 SER B CA 1 ATOM 6239 C C . SER B 1 373 ? 23.869 -14.869 9.250 1.00 17.37 ? 373 SER B C 1 ATOM 6240 O O . SER B 1 373 ? 23.927 -14.657 8.033 1.00 17.72 ? 373 SER B O 1 ATOM 6241 C CB . SER B 1 373 ? 22.466 -13.370 10.701 1.00 18.25 ? 373 SER B CB 1 ATOM 6242 O OG . SER B 1 373 ? 21.478 -13.628 9.699 1.00 18.14 ? 373 SER B OG 1 ATOM 6243 N N . SER B 1 374 ? 23.821 -16.088 9.770 1.00 16.27 ? 374 SER B N 1 ATOM 6244 C CA . SER B 1 374 ? 23.753 -17.244 8.887 1.00 16.71 ? 374 SER B CA 1 ATOM 6245 C C . SER B 1 374 ? 22.596 -17.093 7.974 1.00 16.08 ? 374 SER B C 1 ATOM 6246 O O . SER B 1 374 ? 22.759 -17.148 6.766 1.00 17.00 ? 374 SER B O 1 ATOM 6247 C CB . SER B 1 374 ? 23.545 -18.527 9.638 1.00 15.70 ? 374 SER B CB 1 ATOM 6248 O OG . SER B 1 374 ? 24.786 -18.923 10.067 1.00 21.48 ? 374 SER B OG 1 ATOM 6249 N N . ALA B 1 375 ? 21.436 -16.855 8.580 1.00 15.75 ? 375 ALA B N 1 ATOM 6250 C CA . ALA B 1 375 ? 20.166 -16.858 7.912 1.00 15.91 ? 375 ALA B CA 1 ATOM 6251 C C . ALA B 1 375 ? 20.103 -15.744 6.834 1.00 15.33 ? 375 ALA B C 1 ATOM 6252 O O . ALA B 1 375 ? 19.464 -15.951 5.784 1.00 15.87 ? 375 ALA B O 1 ATOM 6253 C CB . ALA B 1 375 ? 18.996 -16.730 8.965 1.00 15.78 ? 375 ALA B CB 1 ATOM 6254 N N . TRP B 1 376 ? 20.735 -14.594 7.095 1.00 13.83 ? 376 TRP B N 1 ATOM 6255 C CA . TRP B 1 376 ? 20.829 -13.517 6.093 1.00 14.43 ? 376 TRP B CA 1 ATOM 6256 C C . TRP B 1 376 ? 21.912 -13.781 5.031 1.00 14.98 ? 376 TRP B C 1 ATOM 6257 O O . TRP B 1 376 ? 21.975 -13.088 4.030 1.00 16.15 ? 376 TRP B O 1 ATOM 6258 C CB . TRP B 1 376 ? 21.048 -12.148 6.777 1.00 13.07 ? 376 TRP B CB 1 ATOM 6259 C CG . TRP B 1 376 ? 19.800 -11.594 7.386 1.00 14.56 ? 376 TRP B CG 1 ATOM 6260 C CD1 . TRP B 1 376 ? 18.767 -12.312 7.990 1.00 15.40 ? 376 TRP B CD1 1 ATOM 6261 C CD2 . TRP B 1 376 ? 19.412 -10.222 7.444 1.00 14.03 ? 376 TRP B CD2 1 ATOM 6262 N NE1 . TRP B 1 376 ? 17.766 -11.455 8.373 1.00 15.98 ? 376 TRP B NE1 1 ATOM 6263 C CE2 . TRP B 1 376 ? 18.133 -10.172 8.060 1.00 14.25 ? 376 TRP B CE2 1 ATOM 6264 C CE3 . TRP B 1 376 ? 20.005 -9.036 7.013 1.00 13.98 ? 376 TRP B CE3 1 ATOM 6265 C CZ2 . TRP B 1 376 ? 17.453 -8.981 8.268 1.00 14.52 ? 376 TRP B CZ2 1 ATOM 6266 C CZ3 . TRP B 1 376 ? 19.330 -7.842 7.208 1.00 15.69 ? 376 TRP B CZ3 1 ATOM 6267 C CH2 . TRP B 1 376 ? 18.061 -7.824 7.837 1.00 17.41 ? 376 TRP B CH2 1 ATOM 6268 N N . THR B 1 377 ? 22.759 -14.783 5.201 1.00 15.22 ? 377 THR B N 1 ATOM 6269 C CA . THR B 1 377 ? 23.827 -14.969 4.199 1.00 15.84 ? 377 THR B CA 1 ATOM 6270 C C . THR B 1 377 ? 23.792 -16.337 3.507 1.00 15.77 ? 377 THR B C 1 ATOM 6271 O O . THR B 1 377 ? 23.754 -16.421 2.269 1.00 16.19 ? 377 THR B O 1 ATOM 6272 C CB . THR B 1 377 ? 25.233 -14.635 4.763 1.00 15.54 ? 377 THR B CB 1 ATOM 6273 O OG1 . THR B 1 377 ? 25.530 -15.530 5.816 1.00 17.64 ? 377 THR B OG1 1 ATOM 6274 C CG2 . THR B 1 377 ? 25.232 -13.268 5.392 1.00 15.92 ? 377 THR B CG2 1 ATOM 6275 N N . VAL B 1 378 ? 23.804 -17.409 4.299 1.00 16.06 ? 378 VAL B N 1 ATOM 6276 C CA . VAL B 1 378 ? 23.776 -18.760 3.771 1.00 14.95 ? 378 VAL B CA 1 ATOM 6277 C C . VAL B 1 378 ? 22.563 -19.573 4.189 1.00 15.61 ? 378 VAL B C 1 ATOM 6278 O O . VAL B 1 378 ? 22.694 -20.667 4.737 1.00 15.31 ? 378 VAL B O 1 ATOM 6279 C CB . VAL B 1 378 ? 25.042 -19.495 4.140 1.00 15.91 ? 378 VAL B CB 1 ATOM 6280 C CG1 . VAL B 1 378 ? 26.204 -18.766 3.541 1.00 13.32 ? 378 VAL B CG1 1 ATOM 6281 C CG2 . VAL B 1 378 ? 25.184 -19.642 5.756 1.00 15.65 ? 378 VAL B CG2 1 ATOM 6282 N N . PRO B 1 379 ? 21.356 -19.073 3.902 1.00 16.28 ? 379 PRO B N 1 ATOM 6283 C CA . PRO B 1 379 ? 20.217 -19.945 4.135 1.00 16.84 ? 379 PRO B CA 1 ATOM 6284 C C . PRO B 1 379 ? 20.217 -21.041 3.082 1.00 17.91 ? 379 PRO B C 1 ATOM 6285 O O . PRO B 1 379 ? 21.089 -21.033 2.184 1.00 19.05 ? 379 PRO B O 1 ATOM 6286 C CB . PRO B 1 379 ? 19.045 -19.014 3.907 1.00 17.33 ? 379 PRO B CB 1 ATOM 6287 C CG . PRO B 1 379 ? 19.588 -17.955 3.018 1.00 16.92 ? 379 PRO B CG 1 ATOM 6288 C CD . PRO B 1 379 ? 20.943 -17.735 3.460 1.00 15.52 ? 379 PRO B CD 1 ATOM 6289 N N . PHE B 1 380 ? 19.301 -21.999 3.176 1.00 17.95 ? 380 PHE B N 1 ATOM 6290 C CA . PHE B 1 380 ? 19.142 -22.955 2.089 1.00 18.71 ? 380 PHE B CA 1 ATOM 6291 C C . PHE B 1 380 ? 18.875 -22.135 0.816 1.00 18.96 ? 380 PHE B C 1 ATOM 6292 O O . PHE B 1 380 ? 18.080 -21.172 0.857 1.00 18.69 ? 380 PHE B O 1 ATOM 6293 C CB . PHE B 1 380 ? 17.943 -23.878 2.334 1.00 18.75 ? 380 PHE B CB 1 ATOM 6294 C CG . PHE B 1 380 ? 18.211 -24.993 3.289 1.00 19.28 ? 380 PHE B CG 1 ATOM 6295 C CD1 . PHE B 1 380 ? 19.371 -25.759 3.176 1.00 19.27 ? 380 PHE B CD1 1 ATOM 6296 C CD2 . PHE B 1 380 ? 17.294 -25.298 4.280 1.00 20.22 ? 380 PHE B CD2 1 ATOM 6297 C CE1 . PHE B 1 380 ? 19.632 -26.796 4.045 1.00 19.84 ? 380 PHE B CE1 1 ATOM 6298 C CE2 . PHE B 1 380 ? 17.531 -26.339 5.163 1.00 22.74 ? 380 PHE B CE2 1 ATOM 6299 C CZ . PHE B 1 380 ? 18.710 -27.104 5.048 1.00 20.46 ? 380 PHE B CZ 1 ATOM 6300 N N . ALA B 1 381 ? 19.517 -22.527 -0.296 1.00 18.57 ? 381 ALA B N 1 ATOM 6301 C CA . ALA B 1 381 ? 19.336 -21.884 -1.606 1.00 17.95 ? 381 ALA B CA 1 ATOM 6302 C C . ALA B 1 381 ? 19.781 -20.409 -1.630 1.00 17.97 ? 381 ALA B C 1 ATOM 6303 O O . ALA B 1 381 ? 19.292 -19.614 -2.431 1.00 18.48 ? 381 ALA B O 1 ATOM 6304 C CB . ALA B 1 381 ? 17.901 -22.018 -2.048 1.00 17.10 ? 381 ALA B CB 1 ATOM 6305 N N . SER B 1 382 ? 20.678 -20.018 -0.730 1.00 17.32 ? 382 SER B N 1 ATOM 6306 C CA . SER B 1 382 ? 21.153 -18.644 -0.727 1.00 17.18 ? 382 SER B CA 1 ATOM 6307 C C . SER B 1 382 ? 21.741 -18.302 -2.083 1.00 17.01 ? 382 SER B C 1 ATOM 6308 O O . SER B 1 382 ? 22.204 -19.188 -2.810 1.00 16.71 ? 382 SER B O 1 ATOM 6309 C CB . SER B 1 382 ? 22.268 -18.464 0.282 1.00 17.21 ? 382 SER B CB 1 ATOM 6310 O OG . SER B 1 382 ? 23.486 -19.096 -0.176 1.00 19.87 ? 382 SER B OG 1 ATOM 6311 N N . ARG B 1 383 ? 21.744 -17.010 -2.397 1.00 17.16 ? 383 ARG B N 1 ATOM 6312 C CA . ARG B 1 383 ? 22.408 -16.495 -3.589 1.00 17.28 ? 383 ARG B CA 1 ATOM 6313 C C . ARG B 1 383 ? 23.213 -15.211 -3.333 1.00 17.28 ? 383 ARG B C 1 ATOM 6314 O O . ARG B 1 383 ? 22.805 -14.350 -2.552 1.00 17.13 ? 383 ARG B O 1 ATOM 6315 C CB . ARG B 1 383 ? 21.436 -16.390 -4.789 1.00 17.06 ? 383 ARG B CB 1 ATOM 6316 C CG . ARG B 1 383 ? 20.409 -15.304 -4.743 1.00 16.62 ? 383 ARG B CG 1 ATOM 6317 C CD . ARG B 1 383 ? 19.348 -15.511 -3.643 1.00 17.86 ? 383 ARG B CD 1 ATOM 6318 N NE . ARG B 1 383 ? 18.727 -16.842 -3.633 1.00 18.07 ? 383 ARG B NE 1 ATOM 6319 C CZ . ARG B 1 383 ? 17.561 -17.148 -4.191 1.00 16.61 ? 383 ARG B CZ 1 ATOM 6320 N NH1 . ARG B 1 383 ? 16.874 -16.226 -4.842 1.00 16.72 ? 383 ARG B NH1 1 ATOM 6321 N NH2 . ARG B 1 383 ? 17.079 -18.387 -4.094 1.00 14.29 ? 383 ARG B NH2 1 ATOM 6322 N N . LEU B 1 384 ? 24.379 -15.144 -3.968 1.00 16.80 ? 384 LEU B N 1 ATOM 6323 C CA . LEU B 1 384 ? 25.204 -13.946 -4.027 1.00 17.61 ? 384 LEU B CA 1 ATOM 6324 C C . LEU B 1 384 ? 25.173 -13.432 -5.463 1.00 17.38 ? 384 LEU B C 1 ATOM 6325 O O . LEU B 1 384 ? 25.494 -14.199 -6.361 1.00 18.06 ? 384 LEU B O 1 ATOM 6326 C CB . LEU B 1 384 ? 26.673 -14.300 -3.655 1.00 17.83 ? 384 LEU B CB 1 ATOM 6327 C CG . LEU B 1 384 ? 27.740 -13.224 -3.983 1.00 18.13 ? 384 LEU B CG 1 ATOM 6328 C CD1 . LEU B 1 384 ? 27.688 -12.082 -2.921 1.00 19.48 ? 384 LEU B CD1 1 ATOM 6329 C CD2 . LEU B 1 384 ? 29.147 -13.752 -4.149 1.00 11.82 ? 384 LEU B CD2 1 ATOM 6330 N N . TYR B 1 385 ? 24.821 -12.167 -5.701 1.00 16.63 ? 385 TYR B N 1 ATOM 6331 C CA . TYR B 1 385 ? 24.968 -11.596 -7.070 1.00 16.39 ? 385 TYR B CA 1 ATOM 6332 C C . TYR B 1 385 ? 26.090 -10.553 -7.117 1.00 16.41 ? 385 TYR B C 1 ATOM 6333 O O . TYR B 1 385 ? 26.064 -9.563 -6.383 1.00 16.37 ? 385 TYR B O 1 ATOM 6334 C CB . TYR B 1 385 ? 23.691 -10.906 -7.589 1.00 16.20 ? 385 TYR B CB 1 ATOM 6335 C CG . TYR B 1 385 ? 22.400 -11.719 -7.658 1.00 15.65 ? 385 TYR B CG 1 ATOM 6336 C CD1 . TYR B 1 385 ? 22.398 -13.061 -8.029 1.00 14.28 ? 385 TYR B CD1 1 ATOM 6337 C CD2 . TYR B 1 385 ? 21.181 -11.110 -7.401 1.00 15.82 ? 385 TYR B CD2 1 ATOM 6338 C CE1 . TYR B 1 385 ? 21.214 -13.784 -8.087 1.00 14.81 ? 385 TYR B CE1 1 ATOM 6339 C CE2 . TYR B 1 385 ? 19.968 -11.824 -7.460 1.00 17.63 ? 385 TYR B CE2 1 ATOM 6340 C CZ . TYR B 1 385 ? 19.994 -13.159 -7.816 1.00 16.41 ? 385 TYR B CZ 1 ATOM 6341 O OH . TYR B 1 385 ? 18.836 -13.867 -7.895 1.00 15.46 ? 385 TYR B OH 1 ATOM 6342 N N . VAL B 1 386 ? 27.082 -10.763 -7.964 1.00 16.20 ? 386 VAL B N 1 ATOM 6343 C CA . VAL B 1 386 ? 28.028 -9.691 -8.241 1.00 16.28 ? 386 VAL B CA 1 ATOM 6344 C C . VAL B 1 386 ? 27.587 -9.062 -9.575 1.00 17.73 ? 386 VAL B C 1 ATOM 6345 O O . VAL B 1 386 ? 27.433 -9.778 -10.562 1.00 18.50 ? 386 VAL B O 1 ATOM 6346 C CB . VAL B 1 386 ? 29.472 -10.268 -8.321 1.00 16.57 ? 386 VAL B CB 1 ATOM 6347 C CG1 . VAL B 1 386 ? 30.508 -9.214 -8.755 1.00 14.55 ? 386 VAL B CG1 1 ATOM 6348 C CG2 . VAL B 1 386 ? 29.858 -10.955 -6.977 1.00 14.42 ? 386 VAL B CG2 1 ATOM 6349 N N . GLU B 1 387 ? 27.333 -7.756 -9.619 1.00 18.29 ? 387 GLU B N 1 ATOM 6350 C CA . GLU B 1 387 ? 27.146 -7.081 -10.927 1.00 19.93 ? 387 GLU B CA 1 ATOM 6351 C C . GLU B 1 387 ? 28.192 -6.052 -11.205 1.00 20.30 ? 387 GLU B C 1 ATOM 6352 O O . GLU B 1 387 ? 28.846 -5.531 -10.306 1.00 20.89 ? 387 GLU B O 1 ATOM 6353 C CB . GLU B 1 387 ? 25.744 -6.512 -11.157 1.00 18.43 ? 387 GLU B CB 1 ATOM 6354 C CG . GLU B 1 387 ? 25.088 -6.349 -9.916 1.00 21.43 ? 387 GLU B CG 1 ATOM 6355 C CD . GLU B 1 387 ? 23.667 -5.879 -9.967 1.00 21.04 ? 387 GLU B CD 1 ATOM 6356 O OE1 . GLU B 1 387 ? 22.777 -6.689 -10.331 1.00 17.53 ? 387 GLU B OE1 1 ATOM 6357 O OE2 . GLU B 1 387 ? 23.471 -4.713 -9.524 1.00 19.95 ? 387 GLU B OE2 1 ATOM 6358 N N . MET B 1 388 ? 28.368 -5.805 -12.485 1.00 21.29 ? 388 MET B N 1 ATOM 6359 C CA . MET B 1 388 ? 29.174 -4.731 -12.963 1.00 22.43 ? 388 MET B CA 1 ATOM 6360 C C . MET B 1 388 ? 28.213 -3.983 -13.881 1.00 22.76 ? 388 MET B C 1 ATOM 6361 O O . MET B 1 388 ? 27.472 -4.595 -14.594 1.00 22.92 ? 388 MET B O 1 ATOM 6362 C CB . MET B 1 388 ? 30.358 -5.348 -13.667 1.00 22.23 ? 388 MET B CB 1 ATOM 6363 C CG . MET B 1 388 ? 31.511 -4.434 -13.936 1.00 24.32 ? 388 MET B CG 1 ATOM 6364 S SD . MET B 1 388 ? 33.084 -5.357 -13.907 1.00 24.43 ? 388 MET B SD 1 ATOM 6365 C CE . MET B 1 388 ? 32.866 -6.521 -15.269 1.00 24.62 ? 388 MET B CE 1 ATOM 6366 N N . MET B 1 389 ? 28.159 -2.663 -13.811 1.00 24.18 ? 389 MET B N 1 ATOM 6367 C CA . MET B 1 389 ? 27.255 -1.900 -14.648 1.00 25.32 ? 389 MET B CA 1 ATOM 6368 C C . MET B 1 389 ? 28.004 -0.736 -15.213 1.00 27.28 ? 389 MET B C 1 ATOM 6369 O O . MET B 1 389 ? 28.993 -0.298 -14.642 1.00 27.35 ? 389 MET B O 1 ATOM 6370 C CB . MET B 1 389 ? 26.035 -1.397 -13.841 1.00 25.22 ? 389 MET B CB 1 ATOM 6371 C CG . MET B 1 389 ? 26.378 -0.443 -12.703 1.00 22.46 ? 389 MET B CG 1 ATOM 6372 S SD . MET B 1 389 ? 24.961 0.100 -11.728 1.00 25.45 ? 389 MET B SD 1 ATOM 6373 C CE . MET B 1 389 ? 24.166 -1.421 -11.247 1.00 24.72 ? 389 MET B CE 1 ATOM 6374 N N . GLN B 1 390 ? 27.519 -0.239 -16.340 1.00 29.45 ? 390 GLN B N 1 ATOM 6375 C CA . GLN B 1 390 ? 28.060 0.939 -16.985 1.00 31.78 ? 390 GLN B CA 1 ATOM 6376 C C . GLN B 1 390 ? 27.033 2.045 -16.889 1.00 32.70 ? 390 GLN B C 1 ATOM 6377 O O . GLN B 1 390 ? 25.854 1.838 -17.167 1.00 32.92 ? 390 GLN B O 1 ATOM 6378 C CB . GLN B 1 390 ? 28.387 0.657 -18.439 1.00 31.80 ? 390 GLN B CB 1 ATOM 6379 C CG . GLN B 1 390 ? 29.586 1.418 -18.877 1.00 34.18 ? 390 GLN B CG 1 ATOM 6380 C CD . GLN B 1 390 ? 30.866 0.715 -18.509 1.00 37.98 ? 390 GLN B CD 1 ATOM 6381 O OE1 . GLN B 1 390 ? 31.948 1.223 -18.773 1.00 41.91 ? 390 GLN B OE1 1 ATOM 6382 N NE2 . GLN B 1 390 ? 30.756 -0.472 -17.909 1.00 38.70 ? 390 GLN B NE2 1 ATOM 6383 N N . CYS B 1 391 ? 27.473 3.212 -16.454 1.00 34.89 ? 391 CYS B N 1 ATOM 6384 C CA . CYS B 1 391 ? 26.520 4.248 -16.118 1.00 37.71 ? 391 CYS B CA 1 ATOM 6385 C C . CYS B 1 391 ? 26.780 5.491 -16.900 1.00 39.77 ? 391 CYS B C 1 ATOM 6386 O O . CYS B 1 391 ? 27.848 5.642 -17.479 1.00 40.24 ? 391 CYS B O 1 ATOM 6387 C CB . CYS B 1 391 ? 26.506 4.543 -14.623 1.00 37.21 ? 391 CYS B CB 1 ATOM 6388 S SG . CYS B 1 391 ? 25.830 3.195 -13.700 1.00 35.88 ? 391 CYS B SG 1 ATOM 6389 N N . GLN B 1 392 ? 25.782 6.374 -16.893 1.00 42.95 ? 392 GLN B N 1 ATOM 6390 C CA . GLN B 1 392 ? 25.752 7.562 -17.749 1.00 45.62 ? 392 GLN B CA 1 ATOM 6391 C C . GLN B 1 392 ? 26.846 8.535 -17.381 1.00 46.13 ? 392 GLN B C 1 ATOM 6392 O O . GLN B 1 392 ? 27.688 8.892 -18.215 1.00 47.17 ? 392 GLN B O 1 ATOM 6393 C CB . GLN B 1 392 ? 24.372 8.247 -17.728 1.00 46.12 ? 392 GLN B CB 1 ATOM 6394 C CG . GLN B 1 392 ? 23.932 8.739 -19.145 1.00 50.60 ? 392 GLN B CG 1 ATOM 6395 C CD . GLN B 1 392 ? 22.435 9.127 -19.231 1.00 56.12 ? 392 GLN B CD 1 ATOM 6396 O OE1 . GLN B 1 392 ? 21.542 8.351 -18.839 1.00 56.93 ? 392 GLN B OE1 1 ATOM 6397 N NE2 . GLN B 1 392 ? 22.162 10.333 -19.770 1.00 57.71 ? 392 GLN B NE2 1 ATOM 6398 N N . ALA B 1 393 ? 26.867 8.935 -16.119 1.00 46.62 ? 393 ALA B N 1 ATOM 6399 C CA . ALA B 1 393 ? 27.797 9.976 -15.689 1.00 46.84 ? 393 ALA B CA 1 ATOM 6400 C C . ALA B 1 393 ? 29.335 9.653 -15.721 1.00 46.71 ? 393 ALA B C 1 ATOM 6401 O O . ALA B 1 393 ? 30.147 10.583 -15.617 1.00 46.51 ? 393 ALA B O 1 ATOM 6402 C CB . ALA B 1 393 ? 27.352 10.518 -14.293 1.00 47.22 ? 393 ALA B CB 1 ATOM 6403 N N . GLU B 1 394 ? 29.723 8.373 -15.881 1.00 46.37 ? 394 GLU B N 1 ATOM 6404 C CA . GLU B 1 394 ? 31.088 7.885 -15.524 1.00 45.34 ? 394 GLU B CA 1 ATOM 6405 C C . GLU B 1 394 ? 31.716 6.938 -16.556 1.00 44.36 ? 394 GLU B C 1 ATOM 6406 O O . GLU B 1 394 ? 31.034 6.076 -17.082 1.00 44.43 ? 394 GLU B O 1 ATOM 6407 C CB . GLU B 1 394 ? 31.038 7.229 -14.126 1.00 45.44 ? 394 GLU B CB 1 ATOM 6408 C CG . GLU B 1 394 ? 32.143 6.215 -13.780 1.00 46.69 ? 394 GLU B CG 1 ATOM 6409 C CD . GLU B 1 394 ? 33.420 6.830 -13.197 1.00 49.38 ? 394 GLU B CD 1 ATOM 6410 O OE1 . GLU B 1 394 ? 33.353 7.521 -12.148 1.00 49.02 ? 394 GLU B OE1 1 ATOM 6411 O OE2 . GLU B 1 394 ? 34.506 6.589 -13.784 1.00 49.61 ? 394 GLU B OE2 1 ATOM 6412 N N . GLN B 1 395 ? 33.018 7.081 -16.815 1.00 43.02 ? 395 GLN B N 1 ATOM 6413 C CA . GLN B 1 395 ? 33.707 6.271 -17.841 1.00 41.89 ? 395 GLN B CA 1 ATOM 6414 C C . GLN B 1 395 ? 33.968 4.801 -17.458 1.00 40.19 ? 395 GLN B C 1 ATOM 6415 O O . GLN B 1 395 ? 34.077 3.951 -18.342 1.00 39.90 ? 395 GLN B O 1 ATOM 6416 C CB . GLN B 1 395 ? 35.032 6.913 -18.241 1.00 42.29 ? 395 GLN B CB 1 ATOM 6417 C CG . GLN B 1 395 ? 35.099 8.439 -18.014 1.00 47.48 ? 395 GLN B CG 1 ATOM 6418 C CD . GLN B 1 395 ? 36.550 9.006 -18.086 1.00 54.02 ? 395 GLN B CD 1 ATOM 6419 O OE1 . GLN B 1 395 ? 37.493 8.290 -18.467 1.00 55.65 ? 395 GLN B OE1 1 ATOM 6420 N NE2 . GLN B 1 395 ? 36.720 10.294 -17.721 1.00 55.00 ? 395 GLN B NE2 1 ATOM 6421 N N . GLU B 1 396 ? 34.055 4.518 -16.154 1.00 37.79 ? 396 GLU B N 1 ATOM 6422 C CA . GLU B 1 396 ? 34.464 3.200 -15.599 1.00 35.26 ? 396 GLU B CA 1 ATOM 6423 C C . GLU B 1 396 ? 33.303 2.284 -15.163 1.00 32.59 ? 396 GLU B C 1 ATOM 6424 O O . GLU B 1 396 ? 32.248 2.760 -14.716 1.00 32.86 ? 396 GLU B O 1 ATOM 6425 C CB . GLU B 1 396 ? 35.332 3.416 -14.358 1.00 35.56 ? 396 GLU B CB 1 ATOM 6426 C CG . GLU B 1 396 ? 36.845 3.511 -14.584 1.00 38.48 ? 396 GLU B CG 1 ATOM 6427 C CD . GLU B 1 396 ? 37.624 3.428 -13.255 1.00 42.12 ? 396 GLU B CD 1 ATOM 6428 O OE1 . GLU B 1 396 ? 37.765 2.274 -12.717 1.00 43.71 ? 396 GLU B OE1 1 ATOM 6429 O OE2 . GLU B 1 396 ? 38.068 4.511 -12.769 1.00 39.43 ? 396 GLU B OE2 1 ATOM 6430 N N . PRO B 1 397 ? 33.514 0.966 -15.224 1.00 29.24 ? 397 PRO B N 1 ATOM 6431 C CA . PRO B 1 397 ? 32.464 0.115 -14.702 1.00 27.06 ? 397 PRO B CA 1 ATOM 6432 C C . PRO B 1 397 ? 32.354 0.209 -13.175 1.00 25.02 ? 397 PRO B C 1 ATOM 6433 O O . PRO B 1 397 ? 33.346 0.309 -12.505 1.00 23.67 ? 397 PRO B O 1 ATOM 6434 C CB . PRO B 1 397 ? 32.913 -1.291 -15.114 1.00 27.06 ? 397 PRO B CB 1 ATOM 6435 C CG . PRO B 1 397 ? 34.313 -1.133 -15.773 1.00 27.24 ? 397 PRO B CG 1 ATOM 6436 C CD . PRO B 1 397 ? 34.772 0.234 -15.454 1.00 29.07 ? 397 PRO B CD 1 ATOM 6437 N N . LEU B 1 398 ? 31.139 0.195 -12.658 1.00 23.19 ? 398 LEU B N 1 ATOM 6438 C CA . LEU B 1 398 ? 30.871 0.214 -11.234 1.00 22.13 ? 398 LEU B CA 1 ATOM 6439 C C . LEU B 1 398 ? 30.445 -1.210 -10.759 1.00 21.93 ? 398 LEU B C 1 ATOM 6440 O O . LEU B 1 398 ? 29.553 -1.831 -11.366 1.00 22.14 ? 398 LEU B O 1 ATOM 6441 C CB . LEU B 1 398 ? 29.743 1.209 -10.935 1.00 21.73 ? 398 LEU B CB 1 ATOM 6442 C CG . LEU B 1 398 ? 29.907 2.699 -11.284 1.00 20.73 ? 398 LEU B CG 1 ATOM 6443 C CD1 . LEU B 1 398 ? 28.901 3.486 -10.504 1.00 19.43 ? 398 LEU B CD1 1 ATOM 6444 C CD2 . LEU B 1 398 ? 31.318 3.203 -11.005 1.00 19.27 ? 398 LEU B CD2 1 ATOM 6445 N N . VAL B 1 399 ? 31.051 -1.712 -9.674 1.00 19.90 ? 399 VAL B N 1 ATOM 6446 C CA . VAL B 1 399 ? 30.735 -3.020 -9.164 1.00 17.76 ? 399 VAL B CA 1 ATOM 6447 C C . VAL B 1 399 ? 29.667 -2.885 -8.105 1.00 18.51 ? 399 VAL B C 1 ATOM 6448 O O . VAL B 1 399 ? 29.769 -2.033 -7.220 1.00 18.33 ? 399 VAL B O 1 ATOM 6449 C CB . VAL B 1 399 ? 31.937 -3.600 -8.523 1.00 17.85 ? 399 VAL B CB 1 ATOM 6450 C CG1 . VAL B 1 399 ? 31.589 -4.894 -7.786 1.00 17.48 ? 399 VAL B CG1 1 ATOM 6451 C CG2 . VAL B 1 399 ? 33.063 -3.789 -9.545 1.00 16.10 ? 399 VAL B CG2 1 ATOM 6452 N N . ARG B 1 400 ? 28.629 -3.708 -8.153 1.00 18.17 ? 400 ARG B N 1 ATOM 6453 C CA . ARG B 1 400 ? 27.715 -3.735 -7.031 1.00 18.23 ? 400 ARG B CA 1 ATOM 6454 C C . ARG B 1 400 ? 27.519 -5.168 -6.569 1.00 18.61 ? 400 ARG B C 1 ATOM 6455 O O . ARG B 1 400 ? 27.724 -6.090 -7.369 1.00 19.09 ? 400 ARG B O 1 ATOM 6456 C CB . ARG B 1 400 ? 26.414 -3.071 -7.408 1.00 18.53 ? 400 ARG B CB 1 ATOM 6457 C CG . ARG B 1 400 ? 25.249 -3.406 -6.481 1.00 20.29 ? 400 ARG B CG 1 ATOM 6458 C CD . ARG B 1 400 ? 24.036 -2.513 -6.726 1.00 19.85 ? 400 ARG B CD 1 ATOM 6459 N NE . ARG B 1 400 ? 23.219 -3.089 -7.769 1.00 23.06 ? 400 ARG B NE 1 ATOM 6460 C CZ . ARG B 1 400 ? 21.976 -2.719 -8.060 1.00 23.26 ? 400 ARG B CZ 1 ATOM 6461 N NH1 . ARG B 1 400 ? 21.385 -1.773 -7.355 1.00 23.55 ? 400 ARG B NH1 1 ATOM 6462 N NH2 . ARG B 1 400 ? 21.318 -3.324 -9.064 1.00 21.54 ? 400 ARG B NH2 1 ATOM 6463 N N . VAL B 1 401 ? 27.155 -5.372 -5.293 1.00 18.24 ? 401 VAL B N 1 ATOM 6464 C CA . VAL B 1 401 ? 26.964 -6.730 -4.747 1.00 17.26 ? 401 VAL B CA 1 ATOM 6465 C C . VAL B 1 401 ? 25.607 -6.894 -4.045 1.00 17.32 ? 401 VAL B C 1 ATOM 6466 O O . VAL B 1 401 ? 25.276 -6.093 -3.181 1.00 16.41 ? 401 VAL B O 1 ATOM 6467 C CB . VAL B 1 401 ? 28.105 -7.094 -3.788 1.00 16.59 ? 401 VAL B CB 1 ATOM 6468 C CG1 . VAL B 1 401 ? 27.690 -8.184 -2.836 1.00 18.03 ? 401 VAL B CG1 1 ATOM 6469 C CG2 . VAL B 1 401 ? 29.345 -7.564 -4.553 1.00 16.98 ? 401 VAL B CG2 1 ATOM 6470 N N . LEU B 1 402 ? 24.816 -7.922 -4.377 1.00 17.04 ? 402 LEU B N 1 ATOM 6471 C CA . LEU B 1 402 ? 23.654 -8.213 -3.498 1.00 18.14 ? 402 LEU B CA 1 ATOM 6472 C C . LEU B 1 402 ? 23.796 -9.569 -2.845 1.00 18.81 ? 402 LEU B C 1 ATOM 6473 O O . LEU B 1 402 ? 24.283 -10.492 -3.472 1.00 20.27 ? 402 LEU B O 1 ATOM 6474 C CB . LEU B 1 402 ? 22.299 -8.086 -4.230 1.00 18.12 ? 402 LEU B CB 1 ATOM 6475 C CG . LEU B 1 402 ? 22.086 -6.792 -5.073 1.00 17.14 ? 402 LEU B CG 1 ATOM 6476 C CD1 . LEU B 1 402 ? 22.855 -6.834 -6.436 1.00 10.26 ? 402 LEU B CD1 1 ATOM 6477 C CD2 . LEU B 1 402 ? 20.620 -6.589 -5.291 1.00 13.44 ? 402 LEU B CD2 1 ATOM 6478 N N . VAL B 1 403 ? 23.377 -9.685 -1.584 1.00 19.41 ? 403 VAL B N 1 ATOM 6479 C CA . VAL B 1 403 ? 23.435 -10.943 -0.803 1.00 18.87 ? 403 VAL B CA 1 ATOM 6480 C C . VAL B 1 403 ? 22.001 -11.228 -0.346 1.00 18.81 ? 403 VAL B C 1 ATOM 6481 O O . VAL B 1 403 ? 21.456 -10.501 0.460 1.00 18.36 ? 403 VAL B O 1 ATOM 6482 C CB . VAL B 1 403 ? 24.409 -10.789 0.389 1.00 18.80 ? 403 VAL B CB 1 ATOM 6483 C CG1 . VAL B 1 403 ? 24.355 -11.969 1.333 1.00 18.48 ? 403 VAL B CG1 1 ATOM 6484 C CG2 . VAL B 1 403 ? 25.810 -10.596 -0.132 1.00 19.01 ? 403 VAL B CG2 1 ATOM 6485 N N . ASN B 1 404 ? 21.406 -12.261 -0.945 1.00 19.47 ? 404 ASN B N 1 ATOM 6486 C CA . ASN B 1 404 ? 19.977 -12.594 -0.859 1.00 19.68 ? 404 ASN B CA 1 ATOM 6487 C C . ASN B 1 404 ? 18.976 -11.462 -1.062 1.00 20.37 ? 404 ASN B C 1 ATOM 6488 O O . ASN B 1 404 ? 17.991 -11.372 -0.334 1.00 20.85 ? 404 ASN B O 1 ATOM 6489 C CB . ASN B 1 404 ? 19.662 -13.340 0.429 1.00 19.92 ? 404 ASN B CB 1 ATOM 6490 C CG . ASN B 1 404 ? 20.411 -14.638 0.543 1.00 19.42 ? 404 ASN B CG 1 ATOM 6491 O OD1 . ASN B 1 404 ? 20.199 -15.589 -0.209 1.00 16.73 ? 404 ASN B OD1 1 ATOM 6492 N ND2 . ASN B 1 404 ? 21.299 -14.680 1.482 1.00 21.61 ? 404 ASN B ND2 1 ATOM 6493 N N . ASP B 1 405 ? 19.235 -10.631 -2.073 1.00 21.24 ? 405 ASP B N 1 ATOM 6494 C CA . ASP B 1 405 ? 18.349 -9.524 -2.563 1.00 21.72 ? 405 ASP B CA 1 ATOM 6495 C C . ASP B 1 405 ? 18.519 -8.204 -1.845 1.00 22.51 ? 405 ASP B C 1 ATOM 6496 O O . ASP B 1 405 ? 17.746 -7.247 -2.077 1.00 23.18 ? 405 ASP B O 1 ATOM 6497 C CB . ASP B 1 405 ? 16.884 -9.931 -2.607 1.00 20.36 ? 405 ASP B CB 1 ATOM 6498 C CG . ASP B 1 405 ? 16.653 -11.160 -3.472 1.00 22.11 ? 405 ASP B CG 1 ATOM 6499 O OD1 . ASP B 1 405 ? 17.550 -11.505 -4.299 1.00 23.72 ? 405 ASP B OD1 1 ATOM 6500 O OD2 . ASP B 1 405 ? 15.585 -11.799 -3.317 1.00 17.83 ? 405 ASP B OD2 1 ATOM 6501 N N . ARG B 1 406 ? 19.530 -8.180 -0.967 1.00 23.20 ? 406 ARG B N 1 ATOM 6502 C CA . ARG B 1 406 ? 19.947 -7.008 -0.185 1.00 23.03 ? 406 ARG B CA 1 ATOM 6503 C C . ARG B 1 406 ? 21.259 -6.429 -0.755 1.00 22.34 ? 406 ARG B C 1 ATOM 6504 O O . ARG B 1 406 ? 22.264 -7.124 -0.875 1.00 22.20 ? 406 ARG B O 1 ATOM 6505 C CB . ARG B 1 406 ? 20.129 -7.404 1.306 1.00 23.10 ? 406 ARG B CB 1 ATOM 6506 C CG . ARG B 1 406 ? 20.598 -6.263 2.197 1.00 25.24 ? 406 ARG B CG 1 ATOM 6507 C CD . ARG B 1 406 ? 21.030 -6.710 3.592 1.00 28.18 ? 406 ARG B CD 1 ATOM 6508 N NE . ARG B 1 406 ? 21.587 -5.593 4.352 1.00 31.65 ? 406 ARG B NE 1 ATOM 6509 C CZ . ARG B 1 406 ? 22.868 -5.470 4.708 1.00 34.15 ? 406 ARG B CZ 1 ATOM 6510 N NH1 . ARG B 1 406 ? 23.760 -6.411 4.408 1.00 32.52 ? 406 ARG B NH1 1 ATOM 6511 N NH2 . ARG B 1 406 ? 23.252 -4.398 5.397 1.00 36.64 ? 406 ARG B NH2 1 ATOM 6512 N N . VAL B 1 407 ? 21.242 -5.161 -1.130 1.00 22.08 ? 407 VAL B N 1 ATOM 6513 C CA . VAL B 1 407 ? 22.476 -4.502 -1.536 1.00 20.57 ? 407 VAL B CA 1 ATOM 6514 C C . VAL B 1 407 ? 23.391 -4.380 -0.307 1.00 21.31 ? 407 VAL B C 1 ATOM 6515 O O . VAL B 1 407 ? 22.964 -3.919 0.757 1.00 21.24 ? 407 VAL B O 1 ATOM 6516 C CB . VAL B 1 407 ? 22.223 -3.121 -2.146 1.00 20.43 ? 407 VAL B CB 1 ATOM 6517 C CG1 . VAL B 1 407 ? 23.506 -2.597 -2.747 1.00 18.28 ? 407 VAL B CG1 1 ATOM 6518 C CG2 . VAL B 1 407 ? 21.135 -3.188 -3.214 1.00 16.69 ? 407 VAL B CG2 1 ATOM 6519 N N . VAL B 1 408 ? 24.642 -4.818 -0.460 1.00 20.93 ? 408 VAL B N 1 ATOM 6520 C CA . VAL B 1 408 ? 25.613 -4.793 0.614 1.00 20.33 ? 408 VAL B CA 1 ATOM 6521 C C . VAL B 1 408 ? 26.707 -3.850 0.135 1.00 20.71 ? 408 VAL B C 1 ATOM 6522 O O . VAL B 1 408 ? 27.336 -4.120 -0.907 1.00 21.12 ? 408 VAL B O 1 ATOM 6523 C CB . VAL B 1 408 ? 26.130 -6.238 0.978 1.00 20.53 ? 408 VAL B CB 1 ATOM 6524 C CG1 . VAL B 1 408 ? 27.156 -6.204 2.108 1.00 20.52 ? 408 VAL B CG1 1 ATOM 6525 C CG2 . VAL B 1 408 ? 24.989 -7.124 1.396 1.00 18.89 ? 408 VAL B CG2 1 ATOM 6526 N N . PRO B 1 409 ? 26.906 -2.724 0.852 1.00 20.27 ? 409 PRO B N 1 ATOM 6527 C CA . PRO B 1 409 ? 27.884 -1.733 0.438 1.00 20.44 ? 409 PRO B CA 1 ATOM 6528 C C . PRO B 1 409 ? 29.298 -2.295 0.450 1.00 20.98 ? 409 PRO B C 1 ATOM 6529 O O . PRO B 1 409 ? 29.745 -2.854 1.455 1.00 22.42 ? 409 PRO B O 1 ATOM 6530 C CB . PRO B 1 409 ? 27.761 -0.629 1.506 1.00 20.44 ? 409 PRO B CB 1 ATOM 6531 C CG . PRO B 1 409 ? 26.407 -0.778 2.067 1.00 21.67 ? 409 PRO B CG 1 ATOM 6532 C CD . PRO B 1 409 ? 26.081 -2.260 1.983 1.00 20.46 ? 409 PRO B CD 1 ATOM 6533 N N . LEU B 1 410 ? 30.017 -2.137 -0.643 1.00 20.55 ? 410 LEU B N 1 ATOM 6534 C CA . LEU B 1 410 ? 31.419 -2.569 -0.682 1.00 21.12 ? 410 LEU B CA 1 ATOM 6535 C C . LEU B 1 410 ? 32.321 -1.929 0.406 1.00 21.35 ? 410 LEU B C 1 ATOM 6536 O O . LEU B 1 410 ? 32.132 -0.743 0.811 1.00 20.70 ? 410 LEU B O 1 ATOM 6537 C CB . LEU B 1 410 ? 31.991 -2.290 -2.067 1.00 20.99 ? 410 LEU B CB 1 ATOM 6538 C CG . LEU B 1 410 ? 31.159 -2.871 -3.233 1.00 20.82 ? 410 LEU B CG 1 ATOM 6539 C CD1 . LEU B 1 410 ? 32.024 -2.872 -4.504 1.00 20.05 ? 410 LEU B CD1 1 ATOM 6540 C CD2 . LEU B 1 410 ? 30.658 -4.271 -2.913 1.00 16.56 ? 410 LEU B CD2 1 ATOM 6541 N N . HIS B 1 411 ? 33.284 -2.710 0.884 1.00 20.72 ? 411 HIS B N 1 ATOM 6542 C CA . HIS B 1 411 ? 34.291 -2.165 1.772 1.00 20.56 ? 411 HIS B CA 1 ATOM 6543 C C . HIS B 1 411 ? 35.634 -2.198 1.077 1.00 20.26 ? 411 HIS B C 1 ATOM 6544 O O . HIS B 1 411 ? 35.834 -2.982 0.130 1.00 19.67 ? 411 HIS B O 1 ATOM 6545 C CB . HIS B 1 411 ? 34.355 -2.955 3.059 1.00 20.71 ? 411 HIS B CB 1 ATOM 6546 C CG . HIS B 1 411 ? 33.243 -2.650 4.012 1.00 20.90 ? 411 HIS B CG 1 ATOM 6547 N ND1 . HIS B 1 411 ? 32.028 -3.295 3.966 1.00 22.33 ? 411 HIS B ND1 1 ATOM 6548 C CD2 . HIS B 1 411 ? 33.175 -1.792 5.055 1.00 21.28 ? 411 HIS B CD2 1 ATOM 6549 C CE1 . HIS B 1 411 ? 31.252 -2.838 4.931 1.00 23.61 ? 411 HIS B CE1 1 ATOM 6550 N NE2 . HIS B 1 411 ? 31.926 -1.923 5.605 1.00 24.47 ? 411 HIS B NE2 1 ATOM 6551 N N . GLY B 1 412 ? 36.541 -1.332 1.538 1.00 20.01 ? 412 GLY B N 1 ATOM 6552 C CA . GLY B 1 412 ? 37.924 -1.333 1.065 1.00 19.16 ? 412 GLY B CA 1 ATOM 6553 C C . GLY B 1 412 ? 38.112 -0.427 -0.133 1.00 19.49 ? 412 GLY B C 1 ATOM 6554 O O . GLY B 1 412 ? 39.180 -0.429 -0.756 1.00 17.75 ? 412 GLY B O 1 ATOM 6555 N N . CYS B 1 413 ? 37.062 0.355 -0.430 1.00 20.19 ? 413 CYS B N 1 ATOM 6556 C CA . CYS B 1 413 ? 37.056 1.265 -1.582 1.00 21.43 ? 413 CYS B CA 1 ATOM 6557 C C . CYS B 1 413 ? 36.057 2.410 -1.424 1.00 21.54 ? 413 CYS B C 1 ATOM 6558 O O . CYS B 1 413 ? 35.120 2.330 -0.585 1.00 22.24 ? 413 CYS B O 1 ATOM 6559 C CB . CYS B 1 413 ? 36.814 0.503 -2.887 1.00 21.44 ? 413 CYS B CB 1 ATOM 6560 S SG . CYS B 1 413 ? 35.366 -0.509 -2.871 1.00 21.98 ? 413 CYS B SG 1 ATOM 6561 N N . PRO B 1 414 ? 36.253 3.505 -2.198 1.00 22.25 ? 414 PRO B N 1 ATOM 6562 C CA . PRO B 1 414 ? 35.327 4.643 -1.973 1.00 22.22 ? 414 PRO B CA 1 ATOM 6563 C C . PRO B 1 414 ? 33.919 4.296 -2.443 1.00 22.50 ? 414 PRO B C 1 ATOM 6564 O O . PRO B 1 414 ? 33.621 4.541 -3.602 1.00 23.47 ? 414 PRO B O 1 ATOM 6565 C CB . PRO B 1 414 ? 35.927 5.794 -2.804 1.00 20.90 ? 414 PRO B CB 1 ATOM 6566 C CG . PRO B 1 414 ? 37.295 5.306 -3.297 1.00 21.81 ? 414 PRO B CG 1 ATOM 6567 C CD . PRO B 1 414 ? 37.294 3.800 -3.217 1.00 21.74 ? 414 PRO B CD 1 ATOM 6568 N N . VAL B 1 415 ? 33.087 3.684 -1.580 1.00 23.16 ? 415 VAL B N 1 ATOM 6569 C CA . VAL B 1 415 ? 31.674 3.419 -1.936 1.00 24.01 ? 415 VAL B CA 1 ATOM 6570 C C . VAL B 1 415 ? 30.923 4.680 -2.147 1.00 24.27 ? 415 VAL B C 1 ATOM 6571 O O . VAL B 1 415 ? 31.202 5.646 -1.460 1.00 25.77 ? 415 VAL B O 1 ATOM 6572 C CB . VAL B 1 415 ? 30.816 2.692 -0.858 1.00 24.57 ? 415 VAL B CB 1 ATOM 6573 C CG1 . VAL B 1 415 ? 30.514 1.277 -1.296 1.00 23.44 ? 415 VAL B CG1 1 ATOM 6574 C CG2 . VAL B 1 415 ? 31.359 2.824 0.585 1.00 23.85 ? 415 VAL B CG2 1 ATOM 6575 N N . ASP B 1 416 ? 29.972 4.662 -3.081 1.00 24.67 ? 416 ASP B N 1 ATOM 6576 C CA . ASP B 1 416 ? 28.997 5.746 -3.259 1.00 24.97 ? 416 ASP B CA 1 ATOM 6577 C C . ASP B 1 416 ? 27.719 5.412 -2.487 1.00 25.39 ? 416 ASP B C 1 ATOM 6578 O O . ASP B 1 416 ? 27.648 4.376 -1.850 1.00 26.16 ? 416 ASP B O 1 ATOM 6579 C CB . ASP B 1 416 ? 28.730 6.000 -4.734 1.00 24.94 ? 416 ASP B CB 1 ATOM 6580 C CG . ASP B 1 416 ? 28.150 4.760 -5.479 1.00 27.00 ? 416 ASP B CG 1 ATOM 6581 O OD1 . ASP B 1 416 ? 27.363 3.976 -4.873 1.00 26.18 ? 416 ASP B OD1 1 ATOM 6582 O OD2 . ASP B 1 416 ? 28.474 4.599 -6.692 1.00 26.72 ? 416 ASP B OD2 1 ATOM 6583 N N . ALA B 1 417 ? 26.720 6.281 -2.508 1.00 26.30 ? 417 ALA B N 1 ATOM 6584 C CA . ALA B 1 417 ? 25.508 6.075 -1.683 1.00 27.22 ? 417 ALA B CA 1 ATOM 6585 C C . ALA B 1 417 ? 24.626 4.918 -2.195 1.00 27.60 ? 417 ALA B C 1 ATOM 6586 O O . ALA B 1 417 ? 23.652 4.542 -1.527 1.00 28.38 ? 417 ALA B O 1 ATOM 6587 C CB . ALA B 1 417 ? 24.672 7.393 -1.583 1.00 27.28 ? 417 ALA B CB 1 ATOM 6588 N N . LEU B 1 418 ? 24.954 4.389 -3.385 1.00 26.88 ? 418 LEU B N 1 ATOM 6589 C CA . LEU B 1 418 ? 24.218 3.283 -3.977 1.00 26.19 ? 418 LEU B CA 1 ATOM 6590 C C . LEU B 1 418 ? 24.941 1.937 -3.745 1.00 25.68 ? 418 LEU B C 1 ATOM 6591 O O . LEU B 1 418 ? 24.593 0.934 -4.365 1.00 25.62 ? 418 LEU B O 1 ATOM 6592 C CB . LEU B 1 418 ? 23.895 3.542 -5.467 1.00 26.01 ? 418 LEU B CB 1 ATOM 6593 C CG . LEU B 1 418 ? 23.034 4.792 -5.792 1.00 26.82 ? 418 LEU B CG 1 ATOM 6594 C CD1 . LEU B 1 418 ? 22.967 5.051 -7.264 1.00 24.86 ? 418 LEU B CD1 1 ATOM 6595 C CD2 . LEU B 1 418 ? 21.617 4.801 -5.175 1.00 25.22 ? 418 LEU B CD2 1 ATOM 6596 N N . GLY B 1 419 ? 25.927 1.924 -2.844 1.00 24.20 ? 419 GLY B N 1 ATOM 6597 C CA . GLY B 1 419 ? 26.649 0.696 -2.523 1.00 23.48 ? 419 GLY B CA 1 ATOM 6598 C C . GLY B 1 419 ? 27.819 0.276 -3.414 1.00 22.91 ? 419 GLY B C 1 ATOM 6599 O O . GLY B 1 419 ? 28.419 -0.757 -3.168 1.00 21.77 ? 419 GLY B O 1 ATOM 6600 N N . ARG B 1 420 ? 28.147 1.080 -4.419 1.00 22.40 ? 420 ARG B N 1 ATOM 6601 C CA . ARG B 1 420 ? 29.030 0.655 -5.517 1.00 23.31 ? 420 ARG B CA 1 ATOM 6602 C C . ARG B 1 420 ? 30.436 1.205 -5.435 1.00 23.13 ? 420 ARG B C 1 ATOM 6603 O O . ARG B 1 420 ? 30.669 2.311 -4.953 1.00 24.96 ? 420 ARG B O 1 ATOM 6604 C CB . ARG B 1 420 ? 28.454 1.061 -6.905 1.00 23.20 ? 420 ARG B CB 1 ATOM 6605 C CG . ARG B 1 420 ? 26.920 0.892 -7.082 1.00 23.78 ? 420 ARG B CG 1 ATOM 6606 C CD . ARG B 1 420 ? 26.430 1.530 -8.391 1.00 24.64 ? 420 ARG B CD 1 ATOM 6607 N NE . ARG B 1 420 ? 26.547 2.994 -8.370 1.00 24.46 ? 420 ARG B NE 1 ATOM 6608 C CZ . ARG B 1 420 ? 25.859 3.826 -9.157 1.00 25.59 ? 420 ARG B CZ 1 ATOM 6609 N NH1 . ARG B 1 420 ? 24.987 3.340 -10.048 1.00 26.03 ? 420 ARG B NH1 1 ATOM 6610 N NH2 . ARG B 1 420 ? 26.031 5.144 -9.051 1.00 20.12 ? 420 ARG B NH2 1 ATOM 6611 N N . CYS B 1 421 ? 31.389 0.468 -5.949 1.00 23.27 ? 421 CYS B N 1 ATOM 6612 C CA . CYS B 1 421 ? 32.707 1.061 -6.174 1.00 23.92 ? 421 CYS B CA 1 ATOM 6613 C C . CYS B 1 421 ? 33.007 0.918 -7.631 1.00 23.58 ? 421 CYS B C 1 ATOM 6614 O O . CYS B 1 421 ? 32.494 0.007 -8.292 1.00 23.88 ? 421 CYS B O 1 ATOM 6615 C CB . CYS B 1 421 ? 33.814 0.346 -5.381 1.00 23.91 ? 421 CYS B CB 1 ATOM 6616 S SG . CYS B 1 421 ? 33.879 0.700 -3.569 1.00 28.13 ? 421 CYS B SG 1 ATOM 6617 N N . THR B 1 422 ? 33.848 1.802 -8.141 1.00 23.21 ? 422 THR B N 1 ATOM 6618 C CA . THR B 1 422 ? 34.460 1.575 -9.447 1.00 23.01 ? 422 THR B CA 1 ATOM 6619 C C . THR B 1 422 ? 35.266 0.267 -9.427 1.00 23.30 ? 422 THR B C 1 ATOM 6620 O O . THR B 1 422 ? 35.862 -0.074 -8.417 1.00 23.92 ? 422 THR B O 1 ATOM 6621 C CB . THR B 1 422 ? 35.426 2.706 -9.848 1.00 22.74 ? 422 THR B CB 1 ATOM 6622 O OG1 . THR B 1 422 ? 36.612 2.554 -9.084 1.00 22.25 ? 422 THR B OG1 1 ATOM 6623 C CG2 . THR B 1 422 ? 34.816 4.115 -9.605 1.00 21.09 ? 422 THR B CG2 1 ATOM 6624 N N . ARG B 1 423 ? 35.315 -0.430 -10.557 1.00 23.44 ? 423 ARG B N 1 ATOM 6625 C CA . ARG B 1 423 ? 35.917 -1.743 -10.633 1.00 23.87 ? 423 ARG B CA 1 ATOM 6626 C C . ARG B 1 423 ? 37.391 -1.730 -10.264 1.00 24.33 ? 423 ARG B C 1 ATOM 6627 O O . ARG B 1 423 ? 37.834 -2.619 -9.535 1.00 24.18 ? 423 ARG B O 1 ATOM 6628 C CB . ARG B 1 423 ? 35.686 -2.377 -12.003 1.00 23.64 ? 423 ARG B CB 1 ATOM 6629 C CG . ARG B 1 423 ? 36.281 -3.781 -12.203 1.00 25.36 ? 423 ARG B CG 1 ATOM 6630 C CD . ARG B 1 423 ? 37.683 -3.781 -12.880 1.00 27.91 ? 423 ARG B CD 1 ATOM 6631 N NE . ARG B 1 423 ? 37.773 -2.855 -14.011 1.00 27.48 ? 423 ARG B NE 1 ATOM 6632 C CZ . ARG B 1 423 ? 37.466 -3.144 -15.279 1.00 29.65 ? 423 ARG B CZ 1 ATOM 6633 N NH1 . ARG B 1 423 ? 37.026 -4.352 -15.637 1.00 29.67 ? 423 ARG B NH1 1 ATOM 6634 N NH2 . ARG B 1 423 ? 37.568 -2.196 -16.204 1.00 26.67 ? 423 ARG B NH2 1 ATOM 6635 N N . ASP B 1 424 ? 38.138 -0.733 -10.747 1.00 25.08 ? 424 ASP B N 1 ATOM 6636 C CA . ASP B 1 424 ? 39.581 -0.663 -10.465 1.00 25.86 ? 424 ASP B CA 1 ATOM 6637 C C . ASP B 1 424 ? 39.845 -0.491 -8.981 1.00 25.29 ? 424 ASP B C 1 ATOM 6638 O O . ASP B 1 424 ? 40.777 -1.093 -8.443 1.00 25.23 ? 424 ASP B O 1 ATOM 6639 C CB . ASP B 1 424 ? 40.294 0.467 -11.234 1.00 26.65 ? 424 ASP B CB 1 ATOM 6640 C CG . ASP B 1 424 ? 40.523 0.134 -12.698 1.00 30.08 ? 424 ASP B CG 1 ATOM 6641 O OD1 . ASP B 1 424 ? 40.304 -1.024 -13.124 1.00 34.32 ? 424 ASP B OD1 1 ATOM 6642 O OD2 . ASP B 1 424 ? 40.935 1.050 -13.434 1.00 34.76 ? 424 ASP B OD2 1 ATOM 6643 N N . SER B 1 425 ? 39.011 0.306 -8.316 1.00 24.39 ? 425 SER B N 1 ATOM 6644 C CA . SER B 1 425 ? 39.229 0.557 -6.897 1.00 23.94 ? 425 SER B CA 1 ATOM 6645 C C . SER B 1 425 ? 38.748 -0.637 -6.044 1.00 23.31 ? 425 SER B C 1 ATOM 6646 O O . SER B 1 425 ? 39.372 -0.963 -5.037 1.00 23.81 ? 425 SER B O 1 ATOM 6647 C CB . SER B 1 425 ? 38.564 1.863 -6.466 1.00 23.09 ? 425 SER B CB 1 ATOM 6648 O OG . SER B 1 425 ? 37.158 1.679 -6.346 1.00 23.72 ? 425 SER B OG 1 ATOM 6649 N N . PHE B 1 426 ? 37.648 -1.276 -6.442 1.00 22.76 ? 426 PHE B N 1 ATOM 6650 C CA . PHE B 1 426 ? 37.222 -2.531 -5.805 1.00 21.79 ? 426 PHE B CA 1 ATOM 6651 C C . PHE B 1 426 ? 38.301 -3.612 -5.877 1.00 21.86 ? 426 PHE B C 1 ATOM 6652 O O . PHE B 1 426 ? 38.515 -4.330 -4.906 1.00 21.57 ? 426 PHE B O 1 ATOM 6653 C CB . PHE B 1 426 ? 35.945 -3.062 -6.419 1.00 20.62 ? 426 PHE B CB 1 ATOM 6654 C CG . PHE B 1 426 ? 35.451 -4.313 -5.781 1.00 19.44 ? 426 PHE B CG 1 ATOM 6655 C CD1 . PHE B 1 426 ? 35.062 -4.312 -4.447 1.00 21.20 ? 426 PHE B CD1 1 ATOM 6656 C CD2 . PHE B 1 426 ? 35.383 -5.501 -6.504 1.00 19.47 ? 426 PHE B CD2 1 ATOM 6657 C CE1 . PHE B 1 426 ? 34.588 -5.466 -3.835 1.00 22.34 ? 426 PHE B CE1 1 ATOM 6658 C CE2 . PHE B 1 426 ? 34.943 -6.682 -5.916 1.00 20.00 ? 426 PHE B CE2 1 ATOM 6659 C CZ . PHE B 1 426 ? 34.522 -6.680 -4.600 1.00 21.62 ? 426 PHE B CZ 1 ATOM 6660 N N . VAL B 1 427 ? 38.977 -3.706 -7.021 1.00 22.23 ? 427 VAL B N 1 ATOM 6661 C CA . VAL B 1 427 ? 40.009 -4.731 -7.215 1.00 22.71 ? 427 VAL B CA 1 ATOM 6662 C C . VAL B 1 427 ? 41.182 -4.426 -6.316 1.00 22.86 ? 427 VAL B C 1 ATOM 6663 O O . VAL B 1 427 ? 41.593 -5.262 -5.499 1.00 23.89 ? 427 VAL B O 1 ATOM 6664 C CB . VAL B 1 427 ? 40.389 -4.945 -8.716 1.00 22.54 ? 427 VAL B CB 1 ATOM 6665 C CG1 . VAL B 1 427 ? 41.740 -5.656 -8.857 1.00 22.21 ? 427 VAL B CG1 1 ATOM 6666 C CG2 . VAL B 1 427 ? 39.324 -5.784 -9.421 1.00 21.31 ? 427 VAL B CG2 1 ATOM 6667 N N . ARG B 1 428 ? 41.660 -3.196 -6.397 1.00 23.78 ? 428 ARG B N 1 ATOM 6668 C CA . ARG B 1 428 ? 42.711 -2.689 -5.494 1.00 24.14 ? 428 ARG B CA 1 ATOM 6669 C C . ARG B 1 428 ? 42.400 -2.913 -4.007 1.00 23.74 ? 428 ARG B C 1 ATOM 6670 O O . ARG B 1 428 ? 43.309 -3.183 -3.247 1.00 24.29 ? 428 ARG B O 1 ATOM 6671 C CB . ARG B 1 428 ? 42.955 -1.217 -5.780 1.00 24.78 ? 428 ARG B CB 1 ATOM 6672 C CG . ARG B 1 428 ? 43.893 -0.485 -4.833 1.00 29.50 ? 428 ARG B CG 1 ATOM 6673 C CD . ARG B 1 428 ? 43.369 0.918 -4.636 1.00 37.11 ? 428 ARG B CD 1 ATOM 6674 N NE . ARG B 1 428 ? 44.430 1.907 -4.437 1.00 45.01 ? 428 ARG B NE 1 ATOM 6675 C CZ . ARG B 1 428 ? 44.405 3.146 -4.948 1.00 48.60 ? 428 ARG B CZ 1 ATOM 6676 N NH1 . ARG B 1 428 ? 43.376 3.532 -5.714 1.00 49.09 ? 428 ARG B NH1 1 ATOM 6677 N NH2 . ARG B 1 428 ? 45.420 3.989 -4.716 1.00 48.39 ? 428 ARG B NH2 1 ATOM 6678 N N . GLY B 1 429 ? 41.132 -2.826 -3.584 1.00 23.37 ? 429 GLY B N 1 ATOM 6679 C CA . GLY B 1 429 ? 40.781 -3.008 -2.159 1.00 22.13 ? 429 GLY B CA 1 ATOM 6680 C C . GLY B 1 429 ? 40.944 -4.452 -1.672 1.00 21.72 ? 429 GLY B C 1 ATOM 6681 O O . GLY B 1 429 ? 41.065 -4.697 -0.473 1.00 22.52 ? 429 GLY B O 1 ATOM 6682 N N . LEU B 1 430 ? 40.961 -5.400 -2.606 1.00 20.02 ? 430 LEU B N 1 ATOM 6683 C CA . LEU B 1 430 ? 41.066 -6.827 -2.287 1.00 18.41 ? 430 LEU B CA 1 ATOM 6684 C C . LEU B 1 430 ? 42.514 -7.302 -2.328 1.00 17.96 ? 430 LEU B C 1 ATOM 6685 O O . LEU B 1 430 ? 42.814 -8.389 -2.833 1.00 17.96 ? 430 LEU B O 1 ATOM 6686 C CB . LEU B 1 430 ? 40.184 -7.674 -3.237 1.00 17.82 ? 430 LEU B CB 1 ATOM 6687 C CG . LEU B 1 430 ? 38.673 -7.376 -3.446 1.00 14.84 ? 430 LEU B CG 1 ATOM 6688 C CD1 . LEU B 1 430 ? 38.194 -8.246 -4.593 1.00 14.68 ? 430 LEU B CD1 1 ATOM 6689 C CD2 . LEU B 1 430 ? 37.781 -7.585 -2.202 1.00 9.26 ? 430 LEU B CD2 1 ATOM 6690 N N . SER B 1 431 ? 43.397 -6.470 -1.779 1.00 18.02 ? 431 SER B N 1 ATOM 6691 C CA . SER B 1 431 ? 44.811 -6.796 -1.538 1.00 18.17 ? 431 SER B CA 1 ATOM 6692 C C . SER B 1 431 ? 44.984 -8.008 -0.667 1.00 18.39 ? 431 SER B C 1 ATOM 6693 O O . SER B 1 431 ? 45.974 -8.722 -0.811 1.00 18.20 ? 431 SER B O 1 ATOM 6694 C CB . SER B 1 431 ? 45.525 -5.622 -0.856 1.00 18.54 ? 431 SER B CB 1 ATOM 6695 O OG . SER B 1 431 ? 44.671 -4.979 0.074 1.00 17.71 ? 431 SER B OG 1 ATOM 6696 N N . PHE B 1 432 ? 44.029 -8.241 0.243 1.00 18.69 ? 432 PHE B N 1 ATOM 6697 C CA . PHE B 1 432 ? 44.120 -9.394 1.129 1.00 19.14 ? 432 PHE B CA 1 ATOM 6698 C C . PHE B 1 432 ? 44.120 -10.620 0.237 1.00 19.65 ? 432 PHE B C 1 ATOM 6699 O O . PHE B 1 432 ? 45.101 -11.339 0.212 1.00 20.19 ? 432 PHE B O 1 ATOM 6700 C CB . PHE B 1 432 ? 43.025 -9.415 2.201 1.00 19.54 ? 432 PHE B CB 1 ATOM 6701 C CG . PHE B 1 432 ? 42.939 -10.733 2.974 1.00 19.77 ? 432 PHE B CG 1 ATOM 6702 C CD1 . PHE B 1 432 ? 43.809 -10.994 4.039 1.00 18.87 ? 432 PHE B CD1 1 ATOM 6703 C CD2 . PHE B 1 432 ? 42.009 -11.695 2.623 1.00 19.77 ? 432 PHE B CD2 1 ATOM 6704 C CE1 . PHE B 1 432 ? 43.759 -12.163 4.727 1.00 18.27 ? 432 PHE B CE1 1 ATOM 6705 C CE2 . PHE B 1 432 ? 41.950 -12.911 3.290 1.00 20.84 ? 432 PHE B CE2 1 ATOM 6706 C CZ . PHE B 1 432 ? 42.834 -13.156 4.353 1.00 20.12 ? 432 PHE B CZ 1 ATOM 6707 N N . ALA B 1 433 ? 43.080 -10.811 -0.575 1.00 19.70 ? 433 ALA B N 1 ATOM 6708 C CA . ALA B 1 433 ? 43.052 -11.972 -1.507 1.00 19.11 ? 433 ALA B CA 1 ATOM 6709 C C . ALA B 1 433 ? 44.196 -11.890 -2.531 1.00 19.41 ? 433 ALA B C 1 ATOM 6710 O O . ALA B 1 433 ? 44.755 -12.915 -2.969 1.00 17.48 ? 433 ALA B O 1 ATOM 6711 C CB . ALA B 1 433 ? 41.703 -12.077 -2.200 1.00 17.78 ? 433 ALA B CB 1 ATOM 6712 N N . ARG B 1 434 ? 44.542 -10.656 -2.913 1.00 20.79 ? 434 ARG B N 1 ATOM 6713 C CA . ARG B 1 434 ? 45.457 -10.489 -4.043 1.00 22.40 ? 434 ARG B CA 1 ATOM 6714 C C . ARG B 1 434 ? 46.851 -10.960 -3.626 1.00 22.63 ? 434 ARG B C 1 ATOM 6715 O O . ARG B 1 434 ? 47.610 -11.447 -4.461 1.00 23.17 ? 434 ARG B O 1 ATOM 6716 C CB . ARG B 1 434 ? 45.469 -9.049 -4.600 1.00 22.13 ? 434 ARG B CB 1 ATOM 6717 C CG . ARG B 1 434 ? 44.539 -8.808 -5.774 1.00 24.41 ? 434 ARG B CG 1 ATOM 6718 C CD . ARG B 1 434 ? 44.747 -7.467 -6.539 1.00 25.24 ? 434 ARG B CD 1 ATOM 6719 N NE . ARG B 1 434 ? 44.732 -6.294 -5.646 1.00 28.97 ? 434 ARG B NE 1 ATOM 6720 C CZ . ARG B 1 434 ? 45.837 -5.651 -5.261 1.00 27.76 ? 434 ARG B CZ 1 ATOM 6721 N NH1 . ARG B 1 434 ? 47.007 -6.049 -5.724 1.00 28.31 ? 434 ARG B NH1 1 ATOM 6722 N NH2 . ARG B 1 434 ? 45.775 -4.616 -4.439 1.00 25.62 ? 434 ARG B NH2 1 ATOM 6723 N N . SER B 1 435 ? 47.158 -10.837 -2.329 1.00 23.12 ? 435 SER B N 1 ATOM 6724 C CA . SER B 1 435 ? 48.479 -11.225 -1.776 1.00 23.41 ? 435 SER B CA 1 ATOM 6725 C C . SER B 1 435 ? 48.545 -12.699 -1.423 1.00 23.14 ? 435 SER B C 1 ATOM 6726 O O . SER B 1 435 ? 49.612 -13.218 -1.071 1.00 23.50 ? 435 SER B O 1 ATOM 6727 C CB . SER B 1 435 ? 48.839 -10.377 -0.550 1.00 23.14 ? 435 SER B CB 1 ATOM 6728 O OG . SER B 1 435 ? 47.760 -10.354 0.391 1.00 23.74 ? 435 SER B OG 1 ATOM 6729 N N . GLY B 1 436 ? 47.407 -13.373 -1.535 1.00 22.91 ? 436 GLY B N 1 ATOM 6730 C CA . GLY B 1 436 ? 47.300 -14.773 -1.119 1.00 22.80 ? 436 GLY B CA 1 ATOM 6731 C C . GLY B 1 436 ? 46.746 -14.977 0.290 1.00 22.66 ? 436 GLY B C 1 ATOM 6732 O O . GLY B 1 436 ? 46.824 -16.083 0.826 1.00 22.04 ? 436 GLY B O 1 ATOM 6733 N N . GLY B 1 437 ? 46.187 -13.917 0.887 1.00 22.22 ? 437 GLY B N 1 ATOM 6734 C CA . GLY B 1 437 ? 45.667 -13.956 2.269 1.00 23.00 ? 437 GLY B CA 1 ATOM 6735 C C . GLY B 1 437 ? 46.683 -14.531 3.229 1.00 23.25 ? 437 GLY B C 1 ATOM 6736 O O . GLY B 1 437 ? 47.854 -14.201 3.116 1.00 24.76 ? 437 GLY B O 1 ATOM 6737 N N . ASP B 1 438 ? 46.258 -15.424 4.125 1.00 22.75 ? 438 ASP B N 1 ATOM 6738 C CA . ASP B 1 438 ? 47.171 -16.141 5.028 1.00 22.62 ? 438 ASP B CA 1 ATOM 6739 C C . ASP B 1 438 ? 47.347 -17.574 4.613 1.00 22.85 ? 438 ASP B C 1 ATOM 6740 O O . ASP B 1 438 ? 47.652 -18.435 5.436 1.00 22.73 ? 438 ASP B O 1 ATOM 6741 C CB . ASP B 1 438 ? 46.689 -16.074 6.489 1.00 21.57 ? 438 ASP B CB 1 ATOM 6742 C CG . ASP B 1 438 ? 46.489 -14.663 6.952 1.00 21.55 ? 438 ASP B CG 1 ATOM 6743 O OD1 . ASP B 1 438 ? 47.369 -13.846 6.682 1.00 22.50 ? 438 ASP B OD1 1 ATOM 6744 O OD2 . ASP B 1 438 ? 45.442 -14.349 7.575 1.00 21.66 ? 438 ASP B OD2 1 ATOM 6745 N N . TRP B 1 439 ? 47.179 -17.836 3.322 1.00 23.55 ? 439 TRP B N 1 ATOM 6746 C CA . TRP B 1 439 ? 47.349 -19.200 2.829 1.00 23.87 ? 439 TRP B CA 1 ATOM 6747 C C . TRP B 1 439 ? 48.666 -19.871 3.312 1.00 25.13 ? 439 TRP B C 1 ATOM 6748 O O . TRP B 1 439 ? 48.650 -21.066 3.589 1.00 24.89 ? 439 TRP B O 1 ATOM 6749 C CB . TRP B 1 439 ? 47.181 -19.294 1.303 1.00 22.39 ? 439 TRP B CB 1 ATOM 6750 C CG . TRP B 1 439 ? 47.004 -20.723 0.839 1.00 21.16 ? 439 TRP B CG 1 ATOM 6751 C CD1 . TRP B 1 439 ? 47.991 -21.568 0.354 1.00 18.70 ? 439 TRP B CD1 1 ATOM 6752 C CD2 . TRP B 1 439 ? 45.794 -21.506 0.874 1.00 18.90 ? 439 TRP B CD2 1 ATOM 6753 N NE1 . TRP B 1 439 ? 47.450 -22.799 0.065 1.00 19.23 ? 439 TRP B NE1 1 ATOM 6754 C CE2 . TRP B 1 439 ? 46.116 -22.796 0.385 1.00 18.15 ? 439 TRP B CE2 1 ATOM 6755 C CE3 . TRP B 1 439 ? 44.465 -21.232 1.239 1.00 18.54 ? 439 TRP B CE3 1 ATOM 6756 C CZ2 . TRP B 1 439 ? 45.163 -23.806 0.256 1.00 18.78 ? 439 TRP B CZ2 1 ATOM 6757 C CZ3 . TRP B 1 439 ? 43.496 -22.248 1.098 1.00 18.17 ? 439 TRP B CZ3 1 ATOM 6758 C CH2 . TRP B 1 439 ? 43.854 -23.516 0.593 1.00 18.22 ? 439 TRP B CH2 1 ATOM 6759 N N . ALA B 1 440 ? 49.777 -19.115 3.437 1.00 26.67 ? 440 ALA B N 1 ATOM 6760 C CA . ALA B 1 440 ? 51.091 -19.694 3.857 1.00 28.35 ? 440 ALA B CA 1 ATOM 6761 C C . ALA B 1 440 ? 51.030 -20.353 5.242 1.00 29.76 ? 440 ALA B C 1 ATOM 6762 O O . ALA B 1 440 ? 51.812 -21.252 5.552 1.00 29.98 ? 440 ALA B O 1 ATOM 6763 C CB . ALA B 1 440 ? 52.233 -18.651 3.793 1.00 27.87 ? 440 ALA B CB 1 ATOM 6764 N N . GLU B 1 441 ? 50.065 -19.927 6.056 1.00 31.61 ? 441 GLU B N 1 ATOM 6765 C CA . GLU B 1 441 ? 49.907 -20.417 7.427 1.00 33.20 ? 441 GLU B CA 1 ATOM 6766 C C . GLU B 1 441 ? 49.134 -21.715 7.486 1.00 33.37 ? 441 GLU B C 1 ATOM 6767 O O . GLU B 1 441 ? 48.871 -22.224 8.568 1.00 33.46 ? 441 GLU B O 1 ATOM 6768 C CB . GLU B 1 441 ? 49.214 -19.348 8.270 1.00 33.89 ? 441 GLU B CB 1 ATOM 6769 C CG . GLU B 1 441 ? 49.978 -18.012 8.242 1.00 37.41 ? 441 GLU B CG 1 ATOM 6770 C CD . GLU B 1 441 ? 49.565 -17.055 9.358 1.00 42.82 ? 441 GLU B CD 1 ATOM 6771 O OE1 . GLU B 1 441 ? 48.877 -17.528 10.306 1.00 44.33 ? 441 GLU B OE1 1 ATOM 6772 O OE2 . GLU B 1 441 ? 49.943 -15.839 9.286 1.00 43.83 ? 441 GLU B OE2 1 ATOM 6773 N N . CYS B 1 442 ? 48.786 -22.249 6.315 1.00 33.81 ? 442 CYS B N 1 ATOM 6774 C CA . CYS B 1 442 ? 48.055 -23.502 6.214 1.00 34.06 ? 442 CYS B CA 1 ATOM 6775 C C . CYS B 1 442 ? 48.950 -24.694 6.598 1.00 35.76 ? 442 CYS B C 1 ATOM 6776 O O . CYS B 1 442 ? 48.468 -25.824 6.851 1.00 35.46 ? 442 CYS B O 1 ATOM 6777 C CB . CYS B 1 442 ? 47.474 -23.678 4.799 1.00 33.36 ? 442 CYS B CB 1 ATOM 6778 S SG . CYS B 1 442 ? 46.025 -22.620 4.304 1.00 29.65 ? 442 CYS B SG 1 ATOM 6779 N N . PHE B 1 443 ? 50.250 -24.433 6.662 1.00 37.85 ? 443 PHE B N 1 ATOM 6780 C CA . PHE B 1 443 ? 51.232 -25.518 6.705 1.00 40.42 ? 443 PHE B CA 1 ATOM 6781 C C . PHE B 1 443 ? 52.208 -25.462 7.874 1.00 41.90 ? 443 PHE B C 1 ATOM 6782 O O . PHE B 1 443 ? 52.530 -26.484 8.456 1.00 42.61 ? 443 PHE B O 1 ATOM 6783 C CB . PHE B 1 443 ? 51.915 -25.643 5.341 1.00 40.50 ? 443 PHE B CB 1 ATOM 6784 C CG . PHE B 1 443 ? 50.928 -25.761 4.205 1.00 40.17 ? 443 PHE B CG 1 ATOM 6785 C CD1 . PHE B 1 443 ? 50.187 -26.942 4.030 1.00 39.68 ? 443 PHE B CD1 1 ATOM 6786 C CD2 . PHE B 1 443 ? 50.687 -24.677 3.360 1.00 40.69 ? 443 PHE B CD2 1 ATOM 6787 C CE1 . PHE B 1 443 ? 49.252 -27.063 3.017 1.00 39.11 ? 443 PHE B CE1 1 ATOM 6788 C CE2 . PHE B 1 443 ? 49.750 -24.782 2.328 1.00 41.53 ? 443 PHE B CE2 1 ATOM 6789 C CZ . PHE B 1 443 ? 49.030 -25.988 2.156 1.00 41.11 ? 443 PHE B CZ 1 ATOM 6790 N N . ALA B 1 444 ? 52.655 -24.273 8.237 1.00 44.13 ? 444 ALA B N 1 ATOM 6791 C CA . ALA B 1 444 ? 53.364 -24.091 9.516 1.00 46.35 ? 444 ALA B CA 1 ATOM 6792 C C . ALA B 1 444 ? 52.396 -23.722 10.696 1.00 47.28 ? 444 ALA B C 1 ATOM 6793 O O . ALA B 1 444 ? 51.964 -24.588 11.500 1.00 47.67 ? 444 ALA B O 1 ATOM 6794 C CB . ALA B 1 444 ? 54.526 -23.039 9.368 1.00 46.92 ? 444 ALA B CB 1 ATOM 6795 O OXT . ALA B 1 444 ? 52.013 -22.543 10.882 1.00 47.45 ? 444 ALA B OXT 1 HETATM 6796 C C1 . NAG C 2 . ? 19.813 23.955 37.726 1.00 40.45 ? 1001 NAG A C1 1 HETATM 6797 C C2 . NAG C 2 . ? 19.193 22.908 38.662 1.00 37.03 ? 1001 NAG A C2 1 HETATM 6798 C C3 . NAG C 2 . ? 18.319 23.533 39.756 1.00 39.46 ? 1001 NAG A C3 1 HETATM 6799 C C4 . NAG C 2 . ? 19.155 24.541 40.503 1.00 40.74 ? 1001 NAG A C4 1 HETATM 6800 C C5 . NAG C 2 . ? 19.497 25.586 39.439 1.00 42.76 ? 1001 NAG A C5 1 HETATM 6801 C C6 . NAG C 2 . ? 20.109 26.876 39.999 1.00 43.97 ? 1001 NAG A C6 1 HETATM 6802 C C7 . NAG C 2 . ? 18.711 20.983 37.187 1.00 29.42 ? 1001 NAG A C7 1 HETATM 6803 C C8 . NAG C 2 . ? 17.551 20.207 36.607 1.00 25.82 ? 1001 NAG A C8 1 HETATM 6804 N N2 . NAG C 2 . ? 18.336 21.993 37.959 1.00 31.92 ? 1001 NAG A N2 1 HETATM 6805 O O3 . NAG C 2 . ? 17.804 22.587 40.674 1.00 38.84 ? 1001 NAG A O3 1 HETATM 6806 O O4 . NAG C 2 . ? 18.414 25.026 41.594 1.00 39.83 ? 1001 NAG A O4 1 HETATM 6807 O O5 . NAG C 2 . ? 20.396 24.945 38.536 1.00 42.19 ? 1001 NAG A O5 1 HETATM 6808 O O6 . NAG C 2 . ? 21.391 26.606 40.535 1.00 46.11 ? 1001 NAG A O6 1 HETATM 6809 O O7 . NAG C 2 . ? 19.887 20.696 36.932 1.00 28.73 ? 1001 NAG A O7 1 HETATM 6810 C C1 . NAG D 2 . ? -28.240 10.769 38.223 1.00 36.11 ? 1002 NAG A C1 1 HETATM 6811 C C2 . NAG D 2 . ? -27.598 11.951 38.985 1.00 41.25 ? 1002 NAG A C2 1 HETATM 6812 C C3 . NAG D 2 . ? -28.280 13.299 38.715 1.00 40.89 ? 1002 NAG A C3 1 HETATM 6813 C C4 . NAG D 2 . ? -28.436 13.558 37.206 1.00 41.68 ? 1002 NAG A C4 1 HETATM 6814 C C5 . NAG D 2 . ? -29.118 12.285 36.623 1.00 42.17 ? 1002 NAG A C5 1 HETATM 6815 C C6 . NAG D 2 . ? -29.577 12.321 35.150 1.00 41.54 ? 1002 NAG A C6 1 HETATM 6816 C C7 . NAG D 2 . ? -26.243 11.338 40.871 1.00 40.54 ? 1002 NAG A C7 1 HETATM 6817 C C8 . NAG D 2 . ? -26.098 11.121 42.344 1.00 41.86 ? 1002 NAG A C8 1 HETATM 6818 N N2 . NAG D 2 . ? -27.430 11.735 40.428 1.00 40.18 ? 1002 NAG A N2 1 HETATM 6819 O O3 . NAG D 2 . ? -27.382 14.203 39.293 1.00 43.81 ? 1002 NAG A O3 1 HETATM 6820 O O4 . NAG D 2 . ? -29.079 14.803 36.882 1.00 39.00 ? 1002 NAG A O4 1 HETATM 6821 O O5 . NAG D 2 . ? -28.288 11.136 36.855 1.00 38.34 ? 1002 NAG A O5 1 HETATM 6822 O O6 . NAG D 2 . ? -28.476 12.428 34.271 1.00 39.43 ? 1002 NAG A O6 1 HETATM 6823 O O7 . NAG D 2 . ? -25.287 11.150 40.120 1.00 38.21 ? 1002 NAG A O7 1 HETATM 6824 C C1 . NAG E 2 . ? -11.812 -12.800 43.870 1.00 24.56 ? 1003 NAG A C1 1 HETATM 6825 C C2 . NAG E 2 . ? -13.214 -13.150 44.331 1.00 25.38 ? 1003 NAG A C2 1 HETATM 6826 C C3 . NAG E 2 . ? -13.693 -12.253 45.459 1.00 27.98 ? 1003 NAG A C3 1 HETATM 6827 C C4 . NAG E 2 . ? -12.583 -12.083 46.512 1.00 29.88 ? 1003 NAG A C4 1 HETATM 6828 C C5 . NAG E 2 . ? -11.211 -11.826 45.863 1.00 30.62 ? 1003 NAG A C5 1 HETATM 6829 C C6 . NAG E 2 . ? -10.051 -11.759 46.855 1.00 30.64 ? 1003 NAG A C6 1 HETATM 6830 C C7 . NAG E 2 . ? -14.394 -14.026 42.457 1.00 29.94 ? 1003 NAG A C7 1 HETATM 6831 C C8 . NAG E 2 . ? -15.240 -13.660 41.285 1.00 29.91 ? 1003 NAG A C8 1 HETATM 6832 N N2 . NAG E 2 . ? -14.044 -12.987 43.188 1.00 27.84 ? 1003 NAG A N2 1 HETATM 6833 O O3 . NAG E 2 . ? -14.887 -12.816 46.005 1.00 28.57 ? 1003 NAG A O3 1 HETATM 6834 O O4 . NAG E 2 . ? -12.877 -11.010 47.386 1.00 32.26 ? 1003 NAG A O4 1 HETATM 6835 O O5 . NAG E 2 . ? -10.948 -12.869 44.960 1.00 28.39 ? 1003 NAG A O5 1 HETATM 6836 O O6 . NAG E 2 . ? -10.483 -10.948 47.889 1.00 30.29 ? 1003 NAG A O6 1 HETATM 6837 O O7 . NAG E 2 . ? -14.069 -15.197 42.716 1.00 30.83 ? 1003 NAG A O7 1 HETATM 6838 C C1 . NAG F 2 . ? 16.104 -43.506 28.308 1.00 44.88 ? 1001 NAG B C1 1 HETATM 6839 C C2 . NAG F 2 . ? 17.138 -42.371 28.359 1.00 44.69 ? 1001 NAG B C2 1 HETATM 6840 C C3 . NAG F 2 . ? 18.571 -42.903 28.280 1.00 46.31 ? 1001 NAG B C3 1 HETATM 6841 C C4 . NAG F 2 . ? 18.787 -43.937 29.379 1.00 47.44 ? 1001 NAG B C4 1 HETATM 6842 C C5 . NAG F 2 . ? 17.747 -45.055 29.184 1.00 49.07 ? 1001 NAG B C5 1 HETATM 6843 C C6 . NAG F 2 . ? 17.851 -46.110 30.285 1.00 50.52 ? 1001 NAG B C6 1 HETATM 6844 C C7 . NAG F 2 . ? 16.237 -40.312 27.339 1.00 39.78 ? 1001 NAG B C7 1 HETATM 6845 C C8 . NAG F 2 . ? 16.247 -39.434 26.107 1.00 35.59 ? 1001 NAG B C8 1 HETATM 6846 N N2 . NAG F 2 . ? 16.983 -41.409 27.278 1.00 41.70 ? 1001 NAG B N2 1 HETATM 6847 O O3 . NAG F 2 . ? 19.518 -41.857 28.391 1.00 46.18 ? 1001 NAG B O3 1 HETATM 6848 O O4 . NAG F 2 . ? 20.104 -44.444 29.301 1.00 46.66 ? 1001 NAG B O4 1 HETATM 6849 O O5 . NAG F 2 . ? 16.412 -44.553 29.195 1.00 46.66 ? 1001 NAG B O5 1 HETATM 6850 O O6 . NAG F 2 . ? 17.723 -45.467 31.540 1.00 51.12 ? 1001 NAG B O6 1 HETATM 6851 O O7 . NAG F 2 . ? 15.573 -40.024 28.346 1.00 40.98 ? 1001 NAG B O7 1 HETATM 6852 C C1 . NAG G 2 . ? 42.910 -29.948 -11.573 1.00 38.10 ? 1002 NAG B C1 1 HETATM 6853 C C2 . NAG G 2 . ? 43.144 -31.091 -10.576 1.00 42.57 ? 1002 NAG B C2 1 HETATM 6854 C C3 . NAG G 2 . ? 43.311 -32.425 -11.310 1.00 42.94 ? 1002 NAG B C3 1 HETATM 6855 C C4 . NAG G 2 . ? 42.087 -32.677 -12.191 1.00 43.00 ? 1002 NAG B C4 1 HETATM 6856 C C5 . NAG G 2 . ? 41.844 -31.455 -13.096 1.00 42.33 ? 1002 NAG B C5 1 HETATM 6857 C C6 . NAG G 2 . ? 40.582 -31.532 -13.972 1.00 41.81 ? 1002 NAG B C6 1 HETATM 6858 C C7 . NAG G 2 . ? 44.033 -30.454 -8.387 1.00 40.86 ? 1002 NAG B C7 1 HETATM 6859 C C8 . NAG G 2 . ? 45.267 -30.157 -7.576 1.00 38.90 ? 1002 NAG B C8 1 HETATM 6860 N N2 . NAG G 2 . ? 44.248 -30.797 -9.661 1.00 42.27 ? 1002 NAG B N2 1 HETATM 6861 O O3 . NAG G 2 . ? 43.357 -33.436 -10.332 1.00 45.08 ? 1002 NAG B O3 1 HETATM 6862 O O4 . NAG G 2 . ? 42.203 -33.883 -12.933 1.00 44.91 ? 1002 NAG B O4 1 HETATM 6863 O O5 . NAG G 2 . ? 41.749 -30.287 -12.301 1.00 39.29 ? 1002 NAG B O5 1 HETATM 6864 O O6 . NAG G 2 . ? 39.387 -31.581 -13.209 1.00 39.96 ? 1002 NAG B O6 1 HETATM 6865 O O7 . NAG G 2 . ? 42.897 -30.387 -7.893 1.00 38.66 ? 1002 NAG B O7 1 HETATM 6866 C C1 . NAG H 2 . ? 38.661 -6.553 5.478 1.00 23.37 ? 1003 NAG B C1 1 HETATM 6867 C C2 . NAG H 2 . ? 39.726 -6.161 4.441 1.00 24.62 ? 1003 NAG B C2 1 HETATM 6868 C C3 . NAG H 2 . ? 40.959 -7.025 4.482 1.00 26.31 ? 1003 NAG B C3 1 HETATM 6869 C C4 . NAG H 2 . ? 41.443 -7.225 5.915 1.00 27.25 ? 1003 NAG B C4 1 HETATM 6870 C C5 . NAG H 2 . ? 40.327 -7.636 6.867 1.00 26.27 ? 1003 NAG B C5 1 HETATM 6871 C C6 . NAG H 2 . ? 40.936 -7.727 8.273 1.00 26.29 ? 1003 NAG B C6 1 HETATM 6872 C C7 . NAG H 2 . ? 38.709 -5.238 2.533 1.00 27.35 ? 1003 NAG B C7 1 HETATM 6873 C C8 . NAG H 2 . ? 38.172 -5.468 1.161 1.00 25.75 ? 1003 NAG B C8 1 HETATM 6874 N N2 . NAG H 2 . ? 39.217 -6.308 3.118 1.00 25.30 ? 1003 NAG B N2 1 HETATM 6875 O O3 . NAG H 2 . ? 41.932 -6.348 3.698 1.00 31.21 ? 1003 NAG B O3 1 HETATM 6876 O O4 . NAG H 2 . ? 42.453 -8.227 5.939 1.00 31.14 ? 1003 NAG B O4 1 HETATM 6877 O O5 . NAG H 2 . ? 39.216 -6.735 6.784 1.00 25.16 ? 1003 NAG B O5 1 HETATM 6878 O O6 . NAG H 2 . ? 39.965 -8.168 9.215 1.00 25.44 ? 1003 NAG B O6 1 HETATM 6879 O O7 . NAG H 2 . ? 38.669 -4.134 3.089 1.00 26.42 ? 1003 NAG B O7 1 HETATM 6880 O O . HOH I 3 . ? -7.055 8.136 32.310 1.00 29.96 ? 445 HOH A O 1 HETATM 6881 O O . HOH I 3 . ? -5.608 4.881 45.191 1.00 26.35 ? 446 HOH A O 1 HETATM 6882 O O . HOH I 3 . ? 18.435 11.948 44.966 1.00 29.92 ? 447 HOH A O 1 HETATM 6883 O O . HOH I 3 . ? -11.694 -3.604 54.099 1.00 24.64 ? 448 HOH A O 1 HETATM 6884 O O . HOH I 3 . ? -21.575 13.679 23.720 1.00 22.67 ? 449 HOH A O 1 HETATM 6885 O O . HOH I 3 . ? -8.794 -4.097 29.160 1.00 13.99 ? 450 HOH A O 1 HETATM 6886 O O . HOH I 3 . ? -9.563 17.033 25.747 1.00 34.81 ? 451 HOH A O 1 HETATM 6887 O O . HOH I 3 . ? -10.291 -7.794 23.620 1.00 18.84 ? 452 HOH A O 1 HETATM 6888 O O . HOH I 3 . ? -18.568 0.550 58.036 1.00 35.37 ? 453 HOH A O 1 HETATM 6889 O O . HOH I 3 . ? -18.157 7.679 9.921 1.00 26.95 ? 454 HOH A O 1 HETATM 6890 O O . HOH I 3 . ? 13.480 0.657 48.636 1.00 23.10 ? 455 HOH A O 1 HETATM 6891 O O . HOH I 3 . ? 15.820 6.432 21.111 1.00 29.69 ? 456 HOH A O 1 HETATM 6892 O O . HOH I 3 . ? -22.351 15.837 26.038 1.00 27.63 ? 457 HOH A O 1 HETATM 6893 O O . HOH I 3 . ? -7.169 0.496 18.213 1.00 21.24 ? 458 HOH A O 1 HETATM 6894 O O . HOH I 3 . ? -29.478 -2.421 20.827 1.00 17.58 ? 459 HOH A O 1 HETATM 6895 O O . HOH I 3 . ? -32.589 -1.497 36.526 1.00 20.91 ? 460 HOH A O 1 HETATM 6896 O O . HOH I 3 . ? 9.503 10.786 18.237 1.00 36.00 ? 461 HOH A O 1 HETATM 6897 O O . HOH I 3 . ? -28.547 -7.525 27.734 1.00 27.16 ? 462 HOH A O 1 HETATM 6898 O O . HOH I 3 . ? -27.482 -6.279 39.292 1.00 20.20 ? 463 HOH A O 1 HETATM 6899 O O . HOH I 3 . ? -18.596 0.461 42.823 1.00 10.16 ? 464 HOH A O 1 HETATM 6900 O O . HOH I 3 . ? -12.890 2.074 56.074 1.00 26.80 ? 465 HOH A O 1 HETATM 6901 O O . HOH I 3 . ? -29.745 12.791 42.163 1.00 19.43 ? 466 HOH A O 1 HETATM 6902 O O . HOH I 3 . ? -17.590 -9.945 42.409 1.00 20.60 ? 467 HOH A O 1 HETATM 6903 O O . HOH I 3 . ? 14.516 -1.357 25.374 1.00 37.98 ? 468 HOH A O 1 HETATM 6904 O O . HOH I 3 . ? -26.883 3.467 32.556 1.00 23.55 ? 469 HOH A O 1 HETATM 6905 O O . HOH I 3 . ? -35.174 -2.687 28.999 1.00 17.13 ? 470 HOH A O 1 HETATM 6906 O O . HOH I 3 . ? 18.983 20.839 42.492 1.00 17.22 ? 471 HOH A O 1 HETATM 6907 O O . HOH I 3 . ? -33.638 -3.740 25.396 1.00 27.79 ? 472 HOH A O 1 HETATM 6908 O O . HOH I 3 . ? 2.009 19.325 27.742 1.00 20.20 ? 473 HOH A O 1 HETATM 6909 O O . HOH I 3 . ? 22.372 7.317 29.584 1.00 28.03 ? 474 HOH A O 1 HETATM 6910 O O . HOH I 3 . ? -31.422 -6.331 20.876 1.00 14.53 ? 475 HOH A O 1 HETATM 6911 O O . HOH I 3 . ? 16.410 18.879 40.055 1.00 20.08 ? 476 HOH A O 1 HETATM 6912 O O . HOH I 3 . ? -16.516 -4.976 54.252 1.00 25.80 ? 477 HOH A O 1 HETATM 6913 O O . HOH I 3 . ? 1.313 -8.745 21.132 1.00 20.50 ? 478 HOH A O 1 HETATM 6914 O O . HOH I 3 . ? -18.191 1.069 39.203 1.00 16.26 ? 479 HOH A O 1 HETATM 6915 O O . HOH I 3 . ? -22.922 5.611 36.853 1.00 19.27 ? 480 HOH A O 1 HETATM 6916 O O . HOH I 3 . ? -28.726 7.688 43.525 1.00 36.19 ? 481 HOH A O 1 HETATM 6917 O O . HOH I 3 . ? -17.896 11.212 41.229 1.00 29.83 ? 482 HOH A O 1 HETATM 6918 O O . HOH I 3 . ? -12.226 -3.755 47.877 1.00 29.04 ? 483 HOH A O 1 HETATM 6919 O O . HOH I 3 . ? -27.896 -15.618 25.902 1.00 29.15 ? 484 HOH A O 1 HETATM 6920 O O . HOH I 3 . ? -17.657 -16.342 39.146 1.00 19.97 ? 485 HOH A O 1 HETATM 6921 O O . HOH I 3 . ? 26.018 12.242 18.305 1.00 32.30 ? 486 HOH A O 1 HETATM 6922 O O . HOH I 3 . ? 11.932 28.233 20.513 1.00 32.55 ? 487 HOH A O 1 HETATM 6923 O O . HOH I 3 . ? -9.468 -5.601 19.994 1.00 14.75 ? 488 HOH A O 1 HETATM 6924 O O . HOH I 3 . ? -4.074 20.709 23.539 1.00 31.23 ? 489 HOH A O 1 HETATM 6925 O O . HOH I 3 . ? 21.871 -0.029 33.003 1.00 26.68 ? 490 HOH A O 1 HETATM 6926 O O . HOH I 3 . ? -26.006 3.309 44.378 1.00 23.61 ? 491 HOH A O 1 HETATM 6927 O O . HOH I 3 . ? -34.504 -5.156 22.276 1.00 29.03 ? 492 HOH A O 1 HETATM 6928 O O . HOH I 3 . ? -10.185 12.410 11.327 1.00 32.21 ? 493 HOH A O 1 HETATM 6929 O O . HOH I 3 . ? -10.867 -7.347 12.785 1.00 19.41 ? 494 HOH A O 1 HETATM 6930 O O . HOH I 3 . ? -26.638 11.591 22.046 1.00 23.82 ? 495 HOH A O 1 HETATM 6931 O O . HOH I 3 . ? -23.869 0.848 27.631 1.00 22.27 ? 496 HOH A O 1 HETATM 6932 O O . HOH I 3 . ? -7.823 5.871 53.157 1.00 34.84 ? 497 HOH A O 1 HETATM 6933 O O . HOH I 3 . ? 14.638 2.299 24.042 1.00 19.62 ? 498 HOH A O 1 HETATM 6934 O O . HOH I 3 . ? -10.890 0.717 22.365 1.00 12.30 ? 499 HOH A O 1 HETATM 6935 O O . HOH I 3 . ? -3.599 4.445 15.977 1.00 30.19 ? 500 HOH A O 1 HETATM 6936 O O . HOH I 3 . ? -20.065 -3.332 52.256 1.00 25.83 ? 501 HOH A O 1 HETATM 6937 O O . HOH I 3 . ? 7.591 -5.350 33.457 1.00 26.31 ? 502 HOH A O 1 HETATM 6938 O O . HOH I 3 . ? -4.428 -8.826 28.788 1.00 17.83 ? 503 HOH A O 1 HETATM 6939 O O . HOH I 3 . ? -22.964 7.130 13.146 1.00 39.55 ? 504 HOH A O 1 HETATM 6940 O O . HOH I 3 . ? -14.126 -14.074 36.875 1.00 19.55 ? 505 HOH A O 1 HETATM 6941 O O . HOH I 3 . ? -12.944 -19.705 24.080 1.00 25.08 ? 506 HOH A O 1 HETATM 6942 O O . HOH I 3 . ? -34.835 1.611 25.809 1.00 30.61 ? 507 HOH A O 1 HETATM 6943 O O . HOH I 3 . ? 5.974 7.708 35.790 1.00 40.37 ? 508 HOH A O 1 HETATM 6944 O O . HOH I 3 . ? -12.680 -15.869 29.718 1.00 19.11 ? 509 HOH A O 1 HETATM 6945 O O . HOH I 3 . ? -28.159 1.522 9.369 1.00 34.06 ? 510 HOH A O 1 HETATM 6946 O O . HOH I 3 . ? -35.650 9.478 39.117 1.00 32.82 ? 511 HOH A O 1 HETATM 6947 O O . HOH I 3 . ? -16.882 15.190 21.253 1.00 21.31 ? 512 HOH A O 1 HETATM 6948 O O . HOH I 3 . ? 2.787 -2.361 32.948 1.00 19.27 ? 513 HOH A O 1 HETATM 6949 O O . HOH I 3 . ? -20.149 -21.936 14.869 1.00 26.91 ? 514 HOH A O 1 HETATM 6950 O O . HOH I 3 . ? -28.039 -10.352 14.149 1.00 18.71 ? 515 HOH A O 1 HETATM 6951 O O . HOH I 3 . ? -16.795 3.918 4.884 1.00 33.98 ? 516 HOH A O 1 HETATM 6952 O O . HOH I 3 . ? 26.326 22.480 25.899 1.00 38.61 ? 517 HOH A O 1 HETATM 6953 O O . HOH I 3 . ? -15.997 -13.802 18.823 1.00 34.54 ? 518 HOH A O 1 HETATM 6954 O O . HOH I 3 . ? -29.124 8.803 12.858 1.00 30.59 ? 519 HOH A O 1 HETATM 6955 O O . HOH I 3 . ? -4.494 2.945 11.631 1.00 32.64 ? 520 HOH A O 1 HETATM 6956 O O . HOH I 3 . ? 11.041 26.936 18.177 1.00 23.14 ? 521 HOH A O 1 HETATM 6957 O O . HOH I 3 . ? 3.944 -5.784 30.975 1.00 30.51 ? 522 HOH A O 1 HETATM 6958 O O . HOH I 3 . ? -2.764 1.696 16.561 1.00 24.33 ? 523 HOH A O 1 HETATM 6959 O O . HOH I 3 . ? -18.093 15.361 33.480 1.00 19.24 ? 524 HOH A O 1 HETATM 6960 O O . HOH I 3 . ? 30.483 11.056 24.147 1.00 28.14 ? 525 HOH A O 1 HETATM 6961 O O . HOH I 3 . ? -24.239 -22.942 25.146 1.00 25.74 ? 526 HOH A O 1 HETATM 6962 O O . HOH I 3 . ? 10.426 -7.027 20.908 1.00 38.24 ? 527 HOH A O 1 HETATM 6963 O O . HOH I 3 . ? -19.999 -12.269 13.520 1.00 25.20 ? 528 HOH A O 1 HETATM 6964 O O . HOH I 3 . ? 0.895 -18.408 35.002 1.00 34.71 ? 529 HOH A O 1 HETATM 6965 O O . HOH I 3 . ? -8.312 -9.657 43.431 1.00 26.00 ? 530 HOH A O 1 HETATM 6966 O O . HOH I 3 . ? 3.964 -8.231 35.139 1.00 19.06 ? 531 HOH A O 1 HETATM 6967 O O . HOH I 3 . ? -30.392 -19.836 27.034 1.00 23.98 ? 532 HOH A O 1 HETATM 6968 O O . HOH I 3 . ? -19.336 7.814 41.879 1.00 24.29 ? 533 HOH A O 1 HETATM 6969 O O . HOH I 3 . ? -25.073 -0.211 6.066 1.00 31.50 ? 534 HOH A O 1 HETATM 6970 O O . HOH I 3 . ? -5.125 -13.788 37.650 1.00 46.42 ? 535 HOH A O 1 HETATM 6971 O O . HOH I 3 . ? -19.386 -11.708 6.895 1.00 25.46 ? 536 HOH A O 1 HETATM 6972 O O . HOH I 3 . ? -29.810 -14.684 28.268 1.00 36.29 ? 537 HOH A O 1 HETATM 6973 O O . HOH I 3 . ? -13.822 12.992 18.380 1.00 34.35 ? 538 HOH A O 1 HETATM 6974 O O . HOH I 3 . ? -1.375 6.969 46.902 1.00 35.60 ? 539 HOH A O 1 HETATM 6975 O O . HOH I 3 . ? 5.076 -7.403 32.840 1.00 27.39 ? 540 HOH A O 1 HETATM 6976 O O . HOH I 3 . ? -2.298 -3.877 25.308 1.00 26.36 ? 541 HOH A O 1 HETATM 6977 O O . HOH I 3 . ? -5.709 -14.049 34.416 1.00 35.56 ? 542 HOH A O 1 HETATM 6978 O O . HOH I 3 . ? -6.578 -9.796 17.359 1.00 29.58 ? 543 HOH A O 1 HETATM 6979 O O . HOH I 3 . ? 17.923 16.820 43.705 1.00 22.95 ? 544 HOH A O 1 HETATM 6980 O O . HOH I 3 . ? -26.021 -20.847 40.734 1.00 25.73 ? 545 HOH A O 1 HETATM 6981 O O . HOH I 3 . ? 0.708 6.756 43.154 1.00 37.37 ? 546 HOH A O 1 HETATM 6982 O O . HOH I 3 . ? 0.527 -14.437 40.842 1.00 34.66 ? 547 HOH A O 1 HETATM 6983 O O . HOH I 3 . ? 18.776 30.147 35.344 1.00 30.49 ? 548 HOH A O 1 HETATM 6984 O O . HOH I 3 . ? -25.404 3.835 36.502 1.00 28.85 ? 549 HOH A O 1 HETATM 6985 O O . HOH I 3 . ? -31.550 1.476 39.271 1.00 35.16 ? 550 HOH A O 1 HETATM 6986 O O . HOH I 3 . ? 7.497 16.172 41.897 1.00 33.98 ? 551 HOH A O 1 HETATM 6987 O O . HOH I 3 . ? 7.478 24.967 32.086 1.00 32.41 ? 552 HOH A O 1 HETATM 6988 O O . HOH I 3 . ? -18.489 17.149 20.344 1.00 35.68 ? 553 HOH A O 1 HETATM 6989 O O . HOH I 3 . ? 0.577 -18.190 32.302 1.00 30.75 ? 554 HOH A O 1 HETATM 6990 O O . HOH I 3 . ? -26.549 4.524 20.426 1.00 36.27 ? 555 HOH A O 1 HETATM 6991 O O . HOH I 3 . ? -25.656 2.375 7.953 1.00 24.85 ? 556 HOH A O 1 HETATM 6992 O O . HOH I 3 . ? -10.454 -9.946 19.428 1.00 33.30 ? 557 HOH A O 1 HETATM 6993 O O . HOH I 3 . ? 15.792 27.643 29.551 1.00 39.08 ? 558 HOH A O 1 HETATM 6994 O O . HOH I 3 . ? -30.893 11.461 32.114 1.00 38.74 ? 559 HOH A O 1 HETATM 6995 O O . HOH I 3 . ? -19.732 -20.183 40.703 1.00 18.03 ? 560 HOH A O 1 HETATM 6996 O O . HOH I 3 . ? 28.396 6.943 32.282 1.00 27.78 ? 561 HOH A O 1 HETATM 6997 O O . HOH I 3 . ? 11.411 -12.995 34.288 1.00 30.25 ? 562 HOH A O 1 HETATM 6998 O O . HOH I 3 . ? -30.418 -1.227 42.271 1.00 26.51 ? 563 HOH A O 1 HETATM 6999 O O . HOH I 3 . ? -20.095 -8.970 5.952 1.00 43.03 ? 564 HOH A O 1 HETATM 7000 O O . HOH I 3 . ? 8.468 -1.717 49.774 1.00 31.04 ? 565 HOH A O 1 HETATM 7001 O O . HOH I 3 . ? -21.914 -2.974 32.928 1.00 44.30 ? 566 HOH A O 1 HETATM 7002 O O . HOH I 3 . ? -28.728 -12.817 20.831 1.00 24.92 ? 567 HOH A O 1 HETATM 7003 O O . HOH I 3 . ? -36.563 -8.536 34.714 1.00 37.70 ? 568 HOH A O 1 HETATM 7004 O O . HOH I 3 . ? 19.054 2.513 42.205 1.00 33.04 ? 569 HOH A O 1 HETATM 7005 O O . HOH I 3 . ? -30.824 -1.883 16.834 1.00 25.53 ? 570 HOH A O 1 HETATM 7006 O O . HOH I 3 . ? 4.073 -12.244 44.048 1.00 38.53 ? 571 HOH A O 1 HETATM 7007 O O . HOH I 3 . ? -14.865 16.533 38.660 1.00 19.72 ? 572 HOH A O 1 HETATM 7008 O O . HOH I 3 . ? -35.478 4.995 24.639 1.00 35.67 ? 573 HOH A O 1 HETATM 7009 O O . HOH I 3 . ? -2.174 4.692 13.827 1.00 20.18 ? 574 HOH A O 1 HETATM 7010 O O . HOH I 3 . ? -13.788 -28.101 29.566 1.00 25.17 ? 575 HOH A O 1 HETATM 7011 O O . HOH I 3 . ? -29.759 -21.724 19.841 1.00 34.49 ? 576 HOH A O 1 HETATM 7012 O O . HOH I 3 . ? 25.948 16.837 36.883 1.00 30.13 ? 577 HOH A O 1 HETATM 7013 O O . HOH I 3 . ? -23.253 -14.158 16.405 1.00 32.13 ? 578 HOH A O 1 HETATM 7014 O O . HOH I 3 . ? -15.724 11.576 15.687 1.00 29.11 ? 579 HOH A O 1 HETATM 7015 O O . HOH I 3 . ? 2.104 8.764 50.617 1.00 26.35 ? 580 HOH A O 1 HETATM 7016 O O . HOH I 3 . ? 29.556 24.189 26.864 1.00 28.99 ? 581 HOH A O 1 HETATM 7017 O O . HOH I 3 . ? 0.182 -15.390 32.286 1.00 30.02 ? 582 HOH A O 1 HETATM 7018 O O . HOH I 3 . ? -14.692 6.923 44.849 1.00 30.11 ? 583 HOH A O 1 HETATM 7019 O O . HOH I 3 . ? -29.750 -20.128 32.411 1.00 34.73 ? 584 HOH A O 1 HETATM 7020 O O . HOH I 3 . ? 7.789 -15.551 32.196 1.00 43.20 ? 585 HOH A O 1 HETATM 7021 O O . HOH I 3 . ? -25.377 -1.617 14.104 1.00 27.34 ? 586 HOH A O 1 HETATM 7022 O O . HOH I 3 . ? -25.644 -5.241 45.076 1.00 23.86 ? 587 HOH A O 1 HETATM 7023 O O . HOH I 3 . ? -29.333 -13.035 25.245 1.00 39.35 ? 588 HOH A O 1 HETATM 7024 O O . HOH I 3 . ? -5.419 -13.249 44.683 1.00 23.23 ? 589 HOH A O 1 HETATM 7025 O O . HOH I 3 . ? -15.547 -23.450 40.338 1.00 28.61 ? 590 HOH A O 1 HETATM 7026 O O . HOH I 3 . ? -0.242 7.051 36.023 1.00 36.52 ? 591 HOH A O 1 HETATM 7027 O O . HOH I 3 . ? -29.501 0.945 41.191 1.00 38.36 ? 592 HOH A O 1 HETATM 7028 O O . HOH I 3 . ? -14.578 -10.190 42.980 1.00 34.59 ? 593 HOH A O 1 HETATM 7029 O O . HOH I 3 . ? -28.062 -1.035 30.019 1.00 22.59 ? 594 HOH A O 1 HETATM 7030 O O . HOH I 3 . ? -18.476 -13.063 16.926 1.00 45.08 ? 595 HOH A O 1 HETATM 7031 O O . HOH I 3 . ? 9.602 -5.908 25.303 1.00 46.14 ? 596 HOH A O 1 HETATM 7032 O O . HOH I 3 . ? -30.536 -17.726 21.013 1.00 26.51 ? 597 HOH A O 1 HETATM 7033 O O . HOH I 3 . ? -12.186 -8.569 47.413 1.00 36.89 ? 598 HOH A O 1 HETATM 7034 O O . HOH I 3 . ? -33.723 -0.017 8.181 1.00 29.24 ? 599 HOH A O 1 HETATM 7035 O O . HOH I 3 . ? -32.210 -16.830 30.051 1.00 29.57 ? 600 HOH A O 1 HETATM 7036 O O . HOH I 3 . ? 10.382 -1.359 48.081 1.00 36.16 ? 601 HOH A O 1 HETATM 7037 O O . HOH I 3 . ? -9.731 15.187 23.468 1.00 32.43 ? 602 HOH A O 1 HETATM 7038 O O . HOH I 3 . ? -27.246 -6.199 48.496 1.00 34.30 ? 603 HOH A O 1 HETATM 7039 O O . HOH I 3 . ? -27.994 -15.905 36.903 1.00 23.40 ? 604 HOH A O 1 HETATM 7040 O O . HOH I 3 . ? 0.575 8.175 12.178 1.00 33.14 ? 605 HOH A O 1 HETATM 7041 O O . HOH I 3 . ? -34.306 8.503 33.817 1.00 28.30 ? 606 HOH A O 1 HETATM 7042 O O . HOH I 3 . ? -18.360 12.477 15.526 1.00 16.58 ? 607 HOH A O 1 HETATM 7043 O O . HOH I 3 . ? -10.978 -10.137 16.364 1.00 29.52 ? 608 HOH A O 1 HETATM 7044 O O . HOH I 3 . ? -12.933 -8.499 44.579 1.00 30.98 ? 609 HOH A O 1 HETATM 7045 O O . HOH I 3 . ? 9.041 -3.923 51.710 1.00 27.07 ? 610 HOH A O 1 HETATM 7046 O O . HOH I 3 . ? -10.662 15.775 21.077 1.00 20.62 ? 611 HOH A O 1 HETATM 7047 O O . HOH I 3 . ? -31.745 -20.337 21.663 1.00 44.34 ? 612 HOH A O 1 HETATM 7048 O O . HOH I 3 . ? -9.371 18.065 19.598 1.00 22.60 ? 613 HOH A O 1 HETATM 7049 O O . HOH J 3 . ? 26.024 -26.780 3.263 1.00 29.52 ? 445 HOH B O 1 HETATM 7050 O O . HOH J 3 . ? 10.622 -21.445 -2.121 1.00 21.34 ? 446 HOH B O 1 HETATM 7051 O O . HOH J 3 . ? 23.435 -9.644 4.601 1.00 37.78 ? 447 HOH B O 1 HETATM 7052 O O . HOH J 3 . ? 14.477 -19.785 -4.443 1.00 13.34 ? 448 HOH B O 1 HETATM 7053 O O . HOH J 3 . ? 24.857 -15.429 -0.147 1.00 20.20 ? 449 HOH B O 1 HETATM 7054 O O . HOH J 3 . ? 43.279 -11.455 -12.413 1.00 31.25 ? 450 HOH B O 1 HETATM 7055 O O . HOH J 3 . ? 39.275 -9.108 2.568 1.00 30.17 ? 451 HOH B O 1 HETATM 7056 O O . HOH J 3 . ? 22.616 -36.156 -2.893 1.00 30.61 ? 452 HOH B O 1 HETATM 7057 O O . HOH J 3 . ? 13.527 -26.950 -18.324 1.00 23.66 ? 453 HOH B O 1 HETATM 7058 O O . HOH J 3 . ? 43.742 -17.617 -16.226 1.00 19.98 ? 454 HOH B O 1 HETATM 7059 O O . HOH J 3 . ? 0.308 -27.280 13.245 1.00 29.92 ? 455 HOH B O 1 HETATM 7060 O O . HOH J 3 . ? 8.862 -18.182 17.534 1.00 28.77 ? 456 HOH B O 1 HETATM 7061 O O . HOH J 3 . ? 12.164 -10.180 -17.285 1.00 25.68 ? 457 HOH B O 1 HETATM 7062 O O . HOH J 3 . ? 47.122 -26.563 -9.062 1.00 29.15 ? 458 HOH B O 1 HETATM 7063 O O . HOH J 3 . ? 37.112 -23.156 -13.555 1.00 25.13 ? 459 HOH B O 1 HETATM 7064 O O . HOH J 3 . ? 15.660 -21.252 -25.483 1.00 24.75 ? 460 HOH B O 1 HETATM 7065 O O . HOH J 3 . ? 41.627 -19.909 -0.883 1.00 2.05 ? 461 HOH B O 1 HETATM 7066 O O . HOH J 3 . ? 20.979 -11.585 -4.360 1.00 13.83 ? 462 HOH B O 1 HETATM 7067 O O . HOH J 3 . ? 15.199 -9.006 -8.813 1.00 21.56 ? 463 HOH B O 1 HETATM 7068 O O . HOH J 3 . ? 2.796 -44.141 14.167 1.00 34.51 ? 464 HOH B O 1 HETATM 7069 O O . HOH J 3 . ? 25.357 -20.885 -28.204 1.00 22.15 ? 465 HOH B O 1 HETATM 7070 O O . HOH J 3 . ? 5.361 -29.992 9.960 1.00 21.93 ? 466 HOH B O 1 HETATM 7071 O O . HOH J 3 . ? 35.940 -18.026 -15.958 1.00 13.50 ? 467 HOH B O 1 HETATM 7072 O O . HOH J 3 . ? 7.931 -21.818 -10.063 1.00 17.05 ? 468 HOH B O 1 HETATM 7073 O O . HOH J 3 . ? 31.178 -18.587 -21.615 1.00 19.24 ? 469 HOH B O 1 HETATM 7074 O O . HOH J 3 . ? 45.316 -19.871 -10.724 1.00 25.88 ? 470 HOH B O 1 HETATM 7075 O O . HOH J 3 . ? 43.760 -33.835 -7.464 1.00 27.59 ? 471 HOH B O 1 HETATM 7076 O O . HOH J 3 . ? 29.472 -1.445 -22.763 1.00 26.79 ? 472 HOH B O 1 HETATM 7077 O O . HOH J 3 . ? 34.068 -5.062 -0.481 1.00 19.48 ? 473 HOH B O 1 HETATM 7078 O O . HOH J 3 . ? 25.276 -4.791 -22.209 1.00 29.21 ? 474 HOH B O 1 HETATM 7079 O O . HOH J 3 . ? 40.998 -11.148 -21.868 1.00 32.35 ? 475 HOH B O 1 HETATM 7080 O O . HOH J 3 . ? 39.648 -30.757 -1.003 1.00 31.02 ? 476 HOH B O 1 HETATM 7081 O O . HOH J 3 . ? 13.841 -3.678 -2.442 1.00 24.51 ? 477 HOH B O 1 HETATM 7082 O O . HOH J 3 . ? 46.238 -22.773 -6.271 1.00 17.84 ? 478 HOH B O 1 HETATM 7083 O O . HOH J 3 . ? 28.081 -7.073 -21.713 1.00 30.03 ? 479 HOH B O 1 HETATM 7084 O O . HOH J 3 . ? 19.940 -20.122 -5.416 1.00 10.48 ? 480 HOH B O 1 HETATM 7085 O O . HOH J 3 . ? 31.143 -20.075 -13.198 1.00 26.86 ? 481 HOH B O 1 HETATM 7086 O O . HOH J 3 . ? 26.643 -23.636 -19.423 1.00 23.51 ? 482 HOH B O 1 HETATM 7087 O O . HOH J 3 . ? 18.861 -20.793 -27.285 1.00 32.72 ? 483 HOH B O 1 HETATM 7088 O O . HOH J 3 . ? 21.180 -40.114 30.286 1.00 22.56 ? 484 HOH B O 1 HETATM 7089 O O . HOH J 3 . ? 26.888 -33.148 -13.416 1.00 18.87 ? 485 HOH B O 1 HETATM 7090 O O . HOH J 3 . ? 29.704 -5.453 8.003 1.00 34.11 ? 486 HOH B O 1 HETATM 7091 O O . HOH J 3 . ? 42.357 -15.876 7.098 1.00 32.57 ? 487 HOH B O 1 HETATM 7092 O O . HOH J 3 . ? 17.572 -9.619 -6.538 1.00 24.31 ? 488 HOH B O 1 HETATM 7093 O O . HOH J 3 . ? 36.999 -31.196 0.497 1.00 18.25 ? 489 HOH B O 1 HETATM 7094 O O . HOH J 3 . ? 36.658 -8.674 -23.130 1.00 28.68 ? 490 HOH B O 1 HETATM 7095 O O . HOH J 3 . ? 47.790 -16.460 -4.165 1.00 16.18 ? 491 HOH B O 1 HETATM 7096 O O . HOH J 3 . ? 30.691 4.371 -18.664 1.00 45.94 ? 492 HOH B O 1 HETATM 7097 O O . HOH J 3 . ? 39.102 -25.036 -7.780 1.00 18.18 ? 493 HOH B O 1 HETATM 7098 O O . HOH J 3 . ? 15.118 -29.719 4.570 1.00 24.91 ? 494 HOH B O 1 HETATM 7099 O O . HOH J 3 . ? 50.398 -14.140 6.309 1.00 39.09 ? 495 HOH B O 1 HETATM 7100 O O . HOH J 3 . ? 1.426 -23.483 11.870 1.00 24.43 ? 496 HOH B O 1 HETATM 7101 O O . HOH J 3 . ? 40.745 -32.365 11.757 1.00 36.53 ? 497 HOH B O 1 HETATM 7102 O O . HOH J 3 . ? 40.528 -9.169 -0.312 1.00 17.77 ? 498 HOH B O 1 HETATM 7103 O O . HOH J 3 . ? 38.316 -19.918 -2.501 1.00 31.94 ? 499 HOH B O 1 HETATM 7104 O O . HOH J 3 . ? 50.168 -16.463 3.174 1.00 29.15 ? 500 HOH B O 1 HETATM 7105 O O . HOH J 3 . ? 9.289 -20.331 29.069 1.00 31.52 ? 501 HOH B O 1 HETATM 7106 O O . HOH J 3 . ? 20.451 -21.892 30.302 1.00 32.71 ? 502 HOH B O 1 HETATM 7107 O O . HOH J 3 . ? 21.736 -5.162 -18.852 1.00 27.64 ? 503 HOH B O 1 HETATM 7108 O O . HOH J 3 . ? 16.170 1.351 -13.653 1.00 29.24 ? 504 HOH B O 1 HETATM 7109 O O . HOH J 3 . ? 37.483 -3.286 -1.594 1.00 29.42 ? 505 HOH B O 1 HETATM 7110 O O . HOH J 3 . ? 27.194 -3.412 -3.221 1.00 17.44 ? 506 HOH B O 1 HETATM 7111 O O . HOH J 3 . ? 40.128 -23.217 -10.131 1.00 17.76 ? 507 HOH B O 1 HETATM 7112 O O . HOH J 3 . ? 41.022 -26.061 3.643 1.00 20.96 ? 508 HOH B O 1 HETATM 7113 O O . HOH J 3 . ? 30.124 -12.938 -23.468 1.00 21.53 ? 509 HOH B O 1 HETATM 7114 O O . HOH J 3 . ? 29.852 6.371 -8.390 1.00 26.25 ? 510 HOH B O 1 HETATM 7115 O O . HOH J 3 . ? 30.230 -25.546 15.662 1.00 40.68 ? 511 HOH B O 1 HETATM 7116 O O . HOH J 3 . ? 35.754 -0.207 4.320 1.00 33.89 ? 512 HOH B O 1 HETATM 7117 O O . HOH J 3 . ? 26.494 -17.387 -25.276 1.00 25.41 ? 513 HOH B O 1 HETATM 7118 O O . HOH J 3 . ? 19.202 -44.518 14.517 1.00 22.24 ? 514 HOH B O 1 HETATM 7119 O O . HOH J 3 . ? 48.096 -28.326 -16.248 1.00 35.85 ? 515 HOH B O 1 HETATM 7120 O O . HOH J 3 . ? 0.986 -32.435 20.375 1.00 41.24 ? 516 HOH B O 1 HETATM 7121 O O . HOH J 3 . ? 29.344 -20.440 28.884 1.00 25.46 ? 517 HOH B O 1 HETATM 7122 O O . HOH J 3 . ? 9.721 -47.698 16.659 1.00 32.60 ? 518 HOH B O 1 HETATM 7123 O O . HOH J 3 . ? 3.246 -33.275 7.575 1.00 30.24 ? 519 HOH B O 1 HETATM 7124 O O . HOH J 3 . ? 35.618 -26.285 15.455 1.00 29.58 ? 520 HOH B O 1 HETATM 7125 O O . HOH J 3 . ? 5.696 -25.666 29.323 1.00 34.67 ? 521 HOH B O 1 HETATM 7126 O O . HOH J 3 . ? 11.399 -12.959 -18.354 1.00 56.00 ? 522 HOH B O 1 HETATM 7127 O O . HOH J 3 . ? 36.511 -1.177 -18.599 1.00 30.24 ? 523 HOH B O 1 HETATM 7128 O O . HOH J 3 . ? 9.679 -15.744 -19.763 1.00 27.97 ? 524 HOH B O 1 HETATM 7129 O O . HOH J 3 . ? 4.682 -26.574 16.247 1.00 33.28 ? 525 HOH B O 1 HETATM 7130 O O . HOH J 3 . ? 17.539 -15.476 3.331 1.00 18.37 ? 526 HOH B O 1 HETATM 7131 O O . HOH J 3 . ? 20.988 -17.491 -21.989 1.00 16.68 ? 527 HOH B O 1 HETATM 7132 O O . HOH J 3 . ? 48.002 -7.389 -2.356 1.00 40.40 ? 528 HOH B O 1 HETATM 7133 O O . HOH J 3 . ? 7.033 -7.296 0.128 1.00 31.46 ? 529 HOH B O 1 HETATM 7134 O O . HOH J 3 . ? 8.077 -26.483 26.072 1.00 25.28 ? 530 HOH B O 1 HETATM 7135 O O . HOH J 3 . ? 41.368 -19.033 -18.635 1.00 24.53 ? 531 HOH B O 1 HETATM 7136 O O . HOH J 3 . ? 43.954 -17.135 -18.831 1.00 27.52 ? 532 HOH B O 1 HETATM 7137 O O . HOH J 3 . ? 43.669 -24.966 13.894 1.00 32.97 ? 533 HOH B O 1 HETATM 7138 O O . HOH J 3 . ? 7.519 -21.874 -25.538 1.00 39.46 ? 534 HOH B O 1 HETATM 7139 O O . HOH J 3 . ? 44.664 -31.907 1.239 1.00 48.70 ? 535 HOH B O 1 HETATM 7140 O O . HOH J 3 . ? 22.202 0.329 -5.957 1.00 28.71 ? 536 HOH B O 1 HETATM 7141 O O . HOH J 3 . ? 45.984 -30.095 -3.921 1.00 23.08 ? 537 HOH B O 1 HETATM 7142 O O . HOH J 3 . ? 41.084 -26.941 -1.735 1.00 26.02 ? 538 HOH B O 1 HETATM 7143 O O . HOH J 3 . ? 38.840 -16.498 -22.165 1.00 28.39 ? 539 HOH B O 1 HETATM 7144 O O . HOH J 3 . ? 5.413 -34.290 11.503 1.00 29.53 ? 540 HOH B O 1 HETATM 7145 O O . HOH J 3 . ? 22.841 -16.253 26.062 1.00 30.57 ? 541 HOH B O 1 HETATM 7146 O O . HOH J 3 . ? 27.005 3.003 0.505 1.00 28.22 ? 542 HOH B O 1 HETATM 7147 O O . HOH J 3 . ? 29.880 8.182 -19.362 1.00 43.35 ? 543 HOH B O 1 HETATM 7148 O O . HOH J 3 . ? 19.562 -13.946 16.259 1.00 33.73 ? 544 HOH B O 1 HETATM 7149 O O . HOH J 3 . ? 10.279 -5.030 7.239 1.00 34.30 ? 545 HOH B O 1 HETATM 7150 O O . HOH J 3 . ? 44.194 -8.458 -13.131 1.00 46.13 ? 546 HOH B O 1 HETATM 7151 O O . HOH J 3 . ? 12.828 -32.620 36.142 1.00 34.92 ? 547 HOH B O 1 HETATM 7152 O O . HOH J 3 . ? 10.601 -3.191 5.537 1.00 32.12 ? 548 HOH B O 1 HETATM 7153 O O . HOH J 3 . ? 37.708 -2.693 5.324 1.00 33.28 ? 549 HOH B O 1 HETATM 7154 O O . HOH J 3 . ? 23.655 -35.284 -8.351 1.00 19.91 ? 550 HOH B O 1 HETATM 7155 O O . HOH J 3 . ? 18.033 -6.886 -17.692 1.00 13.60 ? 551 HOH B O 1 HETATM 7156 O O . HOH J 3 . ? 17.289 -13.733 -5.652 1.00 22.06 ? 552 HOH B O 1 HETATM 7157 O O . HOH J 3 . ? 28.609 -7.734 16.434 1.00 37.68 ? 553 HOH B O 1 HETATM 7158 O O . HOH J 3 . ? 11.688 -12.196 -10.748 1.00 27.89 ? 554 HOH B O 1 HETATM 7159 O O . HOH J 3 . ? 13.221 -24.396 32.792 1.00 32.09 ? 555 HOH B O 1 HETATM 7160 O O . HOH J 3 . ? 21.324 -16.792 11.746 1.00 21.16 ? 556 HOH B O 1 HETATM 7161 O O . HOH J 3 . ? 12.133 -7.999 -21.150 1.00 33.12 ? 557 HOH B O 1 HETATM 7162 O O . HOH J 3 . ? 9.425 -18.706 -15.424 1.00 31.30 ? 558 HOH B O 1 HETATM 7163 O O . HOH J 3 . ? 14.730 -20.359 27.804 1.00 16.55 ? 559 HOH B O 1 HETATM 7164 O O . HOH J 3 . ? 4.250 -29.599 32.835 1.00 36.95 ? 560 HOH B O 1 HETATM 7165 O O . HOH J 3 . ? 18.495 2.582 -17.229 1.00 28.62 ? 561 HOH B O 1 HETATM 7166 O O . HOH J 3 . ? 50.490 -12.759 10.527 1.00 28.52 ? 562 HOH B O 1 HETATM 7167 O O . HOH J 3 . ? 44.370 -11.362 -8.088 1.00 38.32 ? 563 HOH B O 1 HETATM 7168 O O . HOH J 3 . ? 32.336 -3.670 -17.388 1.00 28.94 ? 564 HOH B O 1 HETATM 7169 O O . HOH J 3 . ? 6.528 -22.161 24.354 1.00 32.66 ? 565 HOH B O 1 HETATM 7170 O O . HOH J 3 . ? 41.158 -3.628 -12.066 1.00 30.14 ? 566 HOH B O 1 HETATM 7171 O O . HOH J 3 . ? 45.197 -9.107 -8.948 1.00 35.77 ? 567 HOH B O 1 HETATM 7172 O O . HOH J 3 . ? 17.463 -19.910 27.331 1.00 24.79 ? 568 HOH B O 1 HETATM 7173 O O . HOH J 3 . ? 9.860 -9.903 -4.948 1.00 36.55 ? 569 HOH B O 1 HETATM 7174 O O . HOH J 3 . ? 48.914 -21.347 -14.076 1.00 39.18 ? 570 HOH B O 1 HETATM 7175 O O . HOH J 3 . ? 24.277 6.533 -11.046 1.00 36.90 ? 571 HOH B O 1 HETATM 7176 O O . HOH J 3 . ? 28.422 -3.314 4.060 1.00 27.05 ? 572 HOH B O 1 HETATM 7177 O O . HOH J 3 . ? 5.001 -21.000 20.266 1.00 34.85 ? 573 HOH B O 1 HETATM 7178 O O . HOH J 3 . ? 5.309 -29.216 7.535 1.00 36.51 ? 574 HOH B O 1 HETATM 7179 O O . HOH J 3 . ? 29.950 3.683 -15.155 1.00 26.28 ? 575 HOH B O 1 HETATM 7180 O O . HOH J 3 . ? 36.999 -12.387 -26.027 1.00 32.44 ? 576 HOH B O 1 HETATM 7181 O O . HOH J 3 . ? 2.352 -37.351 15.604 1.00 37.75 ? 577 HOH B O 1 HETATM 7182 O O . HOH J 3 . ? 7.393 -21.611 16.882 1.00 25.40 ? 578 HOH B O 1 HETATM 7183 O O . HOH J 3 . ? 31.866 -26.057 -21.598 1.00 26.29 ? 579 HOH B O 1 HETATM 7184 O O . HOH J 3 . ? 54.574 -19.880 7.223 1.00 40.16 ? 580 HOH B O 1 HETATM 7185 O O . HOH J 3 . ? 6.093 -34.963 8.929 1.00 30.56 ? 581 HOH B O 1 HETATM 7186 O O . HOH J 3 . ? 15.537 -7.269 -16.765 1.00 19.92 ? 582 HOH B O 1 HETATM 7187 O O . HOH J 3 . ? 17.831 -45.283 20.720 1.00 39.39 ? 583 HOH B O 1 HETATM 7188 O O . HOH J 3 . ? 17.837 -19.133 31.610 1.00 25.59 ? 584 HOH B O 1 HETATM 7189 O O . HOH J 3 . ? 42.289 -28.148 20.390 1.00 35.89 ? 585 HOH B O 1 HETATM 7190 O O . HOH J 3 . ? 43.465 -30.143 21.339 1.00 18.79 ? 586 HOH B O 1 HETATM 7191 O O . HOH J 3 . ? 2.786 -34.585 14.321 1.00 29.54 ? 587 HOH B O 1 HETATM 7192 O O . HOH J 3 . ? 3.784 -37.537 13.180 1.00 30.62 ? 588 HOH B O 1 HETATM 7193 O O . HOH J 3 . ? 6.470 -19.044 -26.124 1.00 39.99 ? 589 HOH B O 1 HETATM 7194 O O . HOH J 3 . ? 18.155 5.162 -19.138 1.00 39.68 ? 590 HOH B O 1 HETATM 7195 O O . HOH J 3 . ? 54.766 -17.185 5.850 1.00 24.69 ? 591 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ALA 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 ARG 3 3 ? ? ? A . n A 1 4 ASN 4 4 ? ? ? A . n A 1 5 GLN 5 5 ? ? ? A . n A 1 6 SER 6 6 ? ? ? A . n A 1 7 SER 7 7 7 SER SER A . n A 1 8 CYS 8 8 8 CYS CYS A . n A 1 9 ASP 9 9 9 ASP ASP A . n A 1 10 THR 10 10 10 THR THR A . n A 1 11 VAL 11 11 11 VAL VAL A . n A 1 12 ASP 12 12 12 ASP ASP A . n A 1 13 GLN 13 13 13 GLN GLN A . n A 1 14 GLY 14 14 14 GLY GLY A . n A 1 15 TYR 15 15 15 TYR TYR A . n A 1 16 GLN 16 16 16 GLN GLN A . n A 1 17 CYS 17 17 17 CYS CYS A . n A 1 18 PHE 18 18 18 PHE PHE A . n A 1 19 SER 19 19 19 SER SER A . n A 1 20 GLU 20 20 20 GLU GLU A . n A 1 21 THR 21 21 21 THR THR A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 HIS 23 23 23 HIS HIS A . n A 1 24 LEU 24 24 24 LEU LEU A . n A 1 25 TRP 25 25 25 TRP TRP A . n A 1 26 GLY 26 26 26 GLY GLY A . n A 1 27 GLN 27 27 27 GLN GLN A . n A 1 28 TYR 28 28 28 TYR TYR A . n A 1 29 ALA 29 29 29 ALA ALA A . n A 1 30 PRO 30 30 30 PRO PRO A . n A 1 31 PHE 31 31 31 PHE PHE A . n A 1 32 PHE 32 32 32 PHE PHE A . n A 1 33 SER 33 33 33 SER SER A . n A 1 34 LEU 34 34 34 LEU LEU A . n A 1 35 ALA 35 35 35 ALA ALA A . n A 1 36 ASN 36 36 36 ASN ASN A . n A 1 37 GLU 37 37 37 GLU GLU A . n A 1 38 SER 38 38 38 SER SER A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 ILE 40 40 40 ILE ILE A . n A 1 41 SER 41 41 41 SER SER A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 GLU 43 43 43 GLU GLU A . n A 1 44 VAL 44 44 44 VAL VAL A . n A 1 45 PRO 45 45 45 PRO PRO A . n A 1 46 ALA 46 46 46 ALA ALA A . n A 1 47 GLY 47 47 47 GLY GLY A . n A 1 48 CYS 48 48 48 CYS CYS A . n A 1 49 ARG 49 49 49 ARG ARG A . n A 1 50 VAL 50 50 50 VAL VAL A . n A 1 51 THR 51 51 51 THR THR A . n A 1 52 PHE 52 52 52 PHE PHE A . n A 1 53 ALA 53 53 53 ALA ALA A . n A 1 54 GLN 54 54 54 GLN GLN A . n A 1 55 VAL 55 55 55 VAL VAL A . n A 1 56 LEU 56 56 56 LEU LEU A . n A 1 57 SER 57 57 57 SER SER A . n A 1 58 ARG 58 58 58 ARG ARG A . n A 1 59 HIS 59 59 59 HIS HIS A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 ALA 61 61 61 ALA ALA A . n A 1 62 ARG 62 62 62 ARG ARG A . n A 1 63 TYR 63 63 63 TYR TYR A . n A 1 64 PRO 64 64 64 PRO PRO A . n A 1 65 THR 65 65 65 THR THR A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 SER 67 67 67 SER SER A . n A 1 68 LYS 68 68 68 LYS LYS A . n A 1 69 GLY 69 69 69 GLY GLY A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 LYS 71 71 71 LYS LYS A . n A 1 72 TYR 72 72 72 TYR TYR A . n A 1 73 SER 73 73 73 SER SER A . n A 1 74 ALA 74 74 74 ALA ALA A . n A 1 75 LEU 75 75 75 LEU LEU A . n A 1 76 ILE 76 76 76 ILE ILE A . n A 1 77 GLU 77 77 77 GLU GLU A . n A 1 78 GLU 78 78 78 GLU GLU A . n A 1 79 ILE 79 79 79 ILE ILE A . n A 1 80 GLN 80 80 80 GLN GLN A . n A 1 81 GLN 81 81 81 GLN GLN A . n A 1 82 ASN 82 82 82 ASN ASN A . n A 1 83 ALA 83 83 83 ALA ALA A . n A 1 84 THR 84 84 84 THR THR A . n A 1 85 THR 85 85 85 THR THR A . n A 1 86 PHE 86 86 86 PHE PHE A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 GLY 88 88 88 GLY GLY A . n A 1 89 LYS 89 89 89 LYS LYS A . n A 1 90 TYR 90 90 90 TYR TYR A . n A 1 91 ALA 91 91 91 ALA ALA A . n A 1 92 PHE 92 92 92 PHE PHE A . n A 1 93 LEU 93 93 93 LEU LEU A . n A 1 94 LYS 94 94 94 LYS LYS A . n A 1 95 THR 95 95 95 THR THR A . n A 1 96 TYR 96 96 96 TYR TYR A . n A 1 97 ASN 97 97 97 ASN ASN A . n A 1 98 TYR 98 98 98 TYR TYR A . n A 1 99 SER 99 99 99 SER SER A . n A 1 100 LEU 100 100 100 LEU LEU A . n A 1 101 GLY 101 101 101 GLY GLY A . n A 1 102 ALA 102 102 102 ALA ALA A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 ASP 104 104 104 ASP ASP A . n A 1 105 LEU 105 105 105 LEU LEU A . n A 1 106 THR 106 106 106 THR THR A . n A 1 107 PRO 107 107 107 PRO PRO A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 GLY 109 109 109 GLY GLY A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 GLN 111 111 111 GLN GLN A . n A 1 112 GLU 112 112 112 GLU GLU A . n A 1 113 LEU 113 113 113 LEU LEU A . n A 1 114 VAL 114 114 114 VAL VAL A . n A 1 115 ASN 115 115 115 ASN ASN A . n A 1 116 SER 116 116 116 SER SER A . n A 1 117 GLY 117 117 117 GLY GLY A . n A 1 118 ILE 118 118 118 ILE ILE A . n A 1 119 LYS 119 119 119 LYS LYS A . n A 1 120 PHE 120 120 120 PHE PHE A . n A 1 121 TYR 121 121 121 TYR TYR A . n A 1 122 GLN 122 122 122 GLN GLN A . n A 1 123 ARG 123 123 123 ARG ARG A . n A 1 124 TYR 124 124 124 TYR TYR A . n A 1 125 GLU 125 125 125 GLU GLU A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 ARG 129 129 129 ARG ARG A . n A 1 130 ASN 130 130 130 ASN ASN A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 VAL 132 132 132 VAL VAL A . n A 1 133 PRO 133 133 133 PRO PRO A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ILE 135 135 135 ILE ILE A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 SER 137 137 137 SER SER A . n A 1 138 SER 138 138 138 SER SER A . n A 1 139 GLY 139 139 139 GLY GLY A . n A 1 140 SER 140 140 140 SER SER A . n A 1 141 SER 141 141 141 SER SER A . n A 1 142 ARG 142 142 142 ARG ARG A . n A 1 143 VAL 143 143 143 VAL VAL A . n A 1 144 ILE 144 144 144 ILE ILE A . n A 1 145 ALA 145 145 145 ALA ALA A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 GLY 147 147 147 GLY GLY A . n A 1 148 LYS 148 148 148 LYS LYS A . n A 1 149 LYS 149 149 149 LYS LYS A . n A 1 150 PHE 150 150 150 PHE PHE A . n A 1 151 ILE 151 151 151 ILE ILE A . n A 1 152 GLU 152 152 152 GLU GLU A . n A 1 153 GLY 153 153 153 GLY GLY A . n A 1 154 PHE 154 154 154 PHE PHE A . n A 1 155 GLN 155 155 155 GLN GLN A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 THR 157 157 157 THR THR A . n A 1 158 LYS 158 158 158 LYS LYS A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LYS 160 160 160 LYS LYS A . n A 1 161 ASP 161 161 161 ASP ASP A . n A 1 162 PRO 162 162 162 PRO PRO A . n A 1 163 ARG 163 163 163 ARG ARG A . n A 1 164 ALA 164 164 164 ALA ALA A . n A 1 165 GLN 165 165 165 GLN GLN A . n A 1 166 PRO 166 166 166 PRO PRO A . n A 1 167 GLY 167 167 167 GLY GLY A . n A 1 168 GLN 168 168 168 GLN GLN A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 SER 170 170 170 SER SER A . n A 1 171 PRO 171 171 171 PRO PRO A . n A 1 172 LYS 172 172 172 LYS LYS A . n A 1 173 ILE 173 173 173 ILE ILE A . n A 1 174 ASP 174 174 174 ASP ASP A . n A 1 175 VAL 175 175 175 VAL VAL A . n A 1 176 VAL 176 176 176 VAL VAL A . n A 1 177 ILE 177 177 177 ILE ILE A . n A 1 178 SER 178 178 178 SER SER A . n A 1 179 GLU 179 179 179 GLU GLU A . n A 1 180 ALA 180 180 180 ALA ALA A . n A 1 181 SER 181 181 181 SER SER A . n A 1 182 SER 182 182 182 SER SER A . n A 1 183 SER 183 183 183 SER SER A . n A 1 184 ASN 184 184 184 ASN ASN A . n A 1 185 ASN 185 185 185 ASN ASN A . n A 1 186 THR 186 186 186 THR THR A . n A 1 187 LEU 187 187 187 LEU LEU A . n A 1 188 ASP 188 188 188 ASP ASP A . n A 1 189 PRO 189 189 189 PRO PRO A . n A 1 190 GLY 190 190 190 GLY GLY A . n A 1 191 THR 191 191 191 THR THR A . n A 1 192 CYS 192 192 192 CYS CYS A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 VAL 194 194 194 VAL VAL A . n A 1 195 PHE 195 195 195 PHE PHE A . n A 1 196 GLU 196 196 196 GLU GLU A . n A 1 197 ASP 197 197 197 ASP ASP A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 GLU 199 199 199 GLU GLU A . n A 1 200 LEU 200 200 200 LEU LEU A . n A 1 201 ALA 201 201 201 ALA ALA A . n A 1 202 ASP 202 202 202 ASP ASP A . n A 1 203 THR 203 203 203 THR THR A . n A 1 204 VAL 204 204 204 VAL VAL A . n A 1 205 GLU 205 205 205 GLU GLU A . n A 1 206 ALA 206 206 206 ALA ALA A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 PHE 208 208 208 PHE PHE A . n A 1 209 THR 209 209 209 THR THR A . n A 1 210 ALA 210 210 210 ALA ALA A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 PHE 212 212 212 PHE PHE A . n A 1 213 VAL 213 213 213 VAL VAL A . n A 1 214 PRO 214 214 214 PRO PRO A . n A 1 215 SER 215 215 215 SER SER A . n A 1 216 ILE 216 216 216 ILE ILE A . n A 1 217 ARG 217 217 217 ARG ARG A . n A 1 218 GLN 218 218 218 GLN GLN A . n A 1 219 ARG 219 219 219 ARG ARG A . n A 1 220 LEU 220 220 220 LEU LEU A . n A 1 221 GLU 221 221 221 GLU GLU A . n A 1 222 ASN 222 222 222 ASN ASN A . n A 1 223 ASP 223 223 223 ASP ASP A . n A 1 224 LEU 224 224 224 LEU LEU A . n A 1 225 SER 225 225 225 SER SER A . n A 1 226 GLY 226 226 226 GLY GLY A . n A 1 227 VAL 227 227 227 VAL VAL A . n A 1 228 THR 228 228 228 THR THR A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 THR 230 230 230 THR THR A . n A 1 231 ASP 231 231 231 ASP ASP A . n A 1 232 THR 232 232 232 THR THR A . n A 1 233 GLU 233 233 233 GLU GLU A . n A 1 234 VAL 234 234 234 VAL VAL A . n A 1 235 THR 235 235 235 THR THR A . n A 1 236 TYR 236 236 236 TYR TYR A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 MET 238 238 238 MET MET A . n A 1 239 ASP 239 239 239 ASP ASP A . n A 1 240 MET 240 240 240 MET MET A . n A 1 241 CYS 241 241 241 CYS CYS A . n A 1 242 SER 242 242 242 SER SER A . n A 1 243 PHE 243 243 243 PHE PHE A . n A 1 244 ASP 244 244 244 ASP ASP A . n A 1 245 THR 245 245 245 THR THR A . n A 1 246 ILE 246 246 246 ILE ILE A . n A 1 247 SER 247 247 247 SER SER A . n A 1 248 THR 248 248 248 THR THR A . n A 1 249 SER 249 249 249 SER SER A . n A 1 250 THR 250 250 250 THR THR A . n A 1 251 VAL 251 251 251 VAL VAL A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 THR 253 253 253 THR THR A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 LEU 255 255 255 LEU LEU A . n A 1 256 SER 256 256 256 SER SER A . n A 1 257 PRO 257 257 257 PRO PRO A . n A 1 258 PHE 258 258 258 PHE PHE A . n A 1 259 CYS 259 259 259 CYS CYS A . n A 1 260 ASP 260 260 260 ASP ASP A . n A 1 261 LEU 261 261 261 LEU LEU A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 THR 263 263 263 THR THR A . n A 1 264 HIS 264 264 264 HIS HIS A . n A 1 265 ASP 265 265 265 ASP ASP A . n A 1 266 GLU 266 266 266 GLU GLU A . n A 1 267 TRP 267 267 267 TRP TRP A . n A 1 268 ILE 268 268 268 ILE ILE A . n A 1 269 ASN 269 269 269 ASN ASN A . n A 1 270 TYR 270 270 270 TYR TYR A . n A 1 271 ASP 271 271 271 ASP ASP A . n A 1 272 TYR 272 272 272 TYR TYR A . n A 1 273 LEU 273 273 273 LEU LEU A . n A 1 274 GLN 274 274 274 GLN GLN A . n A 1 275 SER 275 275 275 SER SER A . n A 1 276 LEU 276 276 276 LEU LEU A . n A 1 277 LYS 277 277 277 LYS LYS A . n A 1 278 LYS 278 278 278 LYS LYS A . n A 1 279 TYR 279 279 279 TYR TYR A . n A 1 280 TYR 280 280 280 TYR TYR A . n A 1 281 GLY 281 281 281 GLY GLY A . n A 1 282 HIS 282 282 282 HIS HIS A . n A 1 283 GLY 283 283 283 GLY GLY A . n A 1 284 ALA 284 284 284 ALA ALA A . n A 1 285 GLY 285 285 285 GLY GLY A . n A 1 286 ASN 286 286 286 ASN ASN A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 LEU 288 288 288 LEU LEU A . n A 1 289 GLY 289 289 289 GLY GLY A . n A 1 290 PRO 290 290 290 PRO PRO A . n A 1 291 THR 291 291 291 THR THR A . n A 1 292 GLN 292 292 292 GLN GLN A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 VAL 294 294 294 VAL VAL A . n A 1 295 GLY 295 295 295 GLY GLY A . n A 1 296 TYR 296 296 296 TYR TYR A . n A 1 297 ALA 297 297 297 ALA ALA A . n A 1 298 ASN 298 298 298 ASN ASN A . n A 1 299 GLU 299 299 299 GLU GLU A . n A 1 300 LEU 300 300 300 LEU LEU A . n A 1 301 ILE 301 301 301 ILE ILE A . n A 1 302 ALA 302 302 302 ALA ALA A . n A 1 303 ARG 303 303 303 ARG ARG A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 HIS 306 306 306 HIS HIS A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 PRO 308 308 308 PRO PRO A . n A 1 309 VAL 309 309 309 VAL VAL A . n A 1 310 HIS 310 310 310 HIS HIS A . n A 1 311 ASP 311 311 311 ASP ASP A . n A 1 312 ASP 312 312 312 ASP ASP A . n A 1 313 THR 313 313 313 THR THR A . n A 1 314 SER 314 314 314 SER SER A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASN 316 316 316 ASN ASN A . n A 1 317 HIS 317 317 317 HIS HIS A . n A 1 318 THR 318 318 318 THR THR A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 SER 321 321 321 SER SER A . n A 1 322 SER 322 322 322 SER SER A . n A 1 323 PRO 323 323 323 PRO PRO A . n A 1 324 ALA 324 324 324 ALA ALA A . n A 1 325 THR 325 325 325 THR THR A . n A 1 326 PHE 326 326 326 PHE PHE A . n A 1 327 PRO 327 327 327 PRO PRO A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 ASN 329 329 329 ASN ASN A . n A 1 330 SER 330 330 330 SER SER A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 LEU 332 332 332 LEU LEU A . n A 1 333 TYR 333 333 333 TYR TYR A . n A 1 334 ALA 334 334 334 ALA ALA A . n A 1 335 ASP 335 335 335 ASP ASP A . n A 1 336 PHE 336 336 336 PHE PHE A . n A 1 337 SER 337 337 337 SER SER A . n A 1 338 HIS 338 338 338 HIS HIS A . n A 1 339 ASP 339 339 339 ASP ASP A . n A 1 340 ASN 340 340 340 ASN ASN A . n A 1 341 GLY 341 341 341 GLY GLY A . n A 1 342 ILE 342 342 342 ILE ILE A . n A 1 343 ILE 343 343 343 ILE ILE A . n A 1 344 SER 344 344 344 SER SER A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 LEU 346 346 346 LEU LEU A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 ALA 348 348 348 ALA ALA A . n A 1 349 LEU 349 349 349 LEU LEU A . n A 1 350 GLY 350 350 350 GLY GLY A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 TYR 352 352 352 TYR TYR A . n A 1 353 ASN 353 353 353 ASN ASN A . n A 1 354 GLY 354 354 354 GLY GLY A . n A 1 355 THR 355 355 355 THR THR A . n A 1 356 LYS 356 356 356 LYS LYS A . n A 1 357 PRO 357 357 357 PRO PRO A . n A 1 358 LEU 358 358 358 LEU LEU A . n A 1 359 SER 359 359 359 SER SER A . n A 1 360 THR 360 360 360 THR THR A . n A 1 361 THR 361 361 361 THR THR A . n A 1 362 THR 362 362 362 THR THR A . n A 1 363 VAL 363 363 363 VAL VAL A . n A 1 364 GLU 364 364 364 GLU GLU A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 ILE 366 366 366 ILE ILE A . n A 1 367 THR 367 367 367 THR THR A . n A 1 368 GLN 368 368 368 GLN GLN A . n A 1 369 THR 369 369 369 THR THR A . n A 1 370 ASP 370 370 370 ASP ASP A . n A 1 371 GLY 371 371 371 GLY GLY A . n A 1 372 PHE 372 372 372 PHE PHE A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 ALA 375 375 375 ALA ALA A . n A 1 376 TRP 376 376 376 TRP TRP A . n A 1 377 THR 377 377 377 THR THR A . n A 1 378 VAL 378 378 378 VAL VAL A . n A 1 379 PRO 379 379 379 PRO PRO A . n A 1 380 PHE 380 380 380 PHE PHE A . n A 1 381 ALA 381 381 381 ALA ALA A . n A 1 382 SER 382 382 382 SER SER A . n A 1 383 ARG 383 383 383 ARG ARG A . n A 1 384 LEU 384 384 384 LEU LEU A . n A 1 385 TYR 385 385 385 TYR TYR A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 GLU 387 387 387 GLU GLU A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 MET 389 389 389 MET MET A . n A 1 390 GLN 390 390 390 GLN GLN A . n A 1 391 CYS 391 391 391 CYS CYS A . n A 1 392 GLN 392 392 392 GLN GLN A . n A 1 393 ALA 393 393 393 ALA ALA A . n A 1 394 GLU 394 394 394 GLU GLU A . n A 1 395 GLN 395 395 395 GLN GLN A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PRO 397 397 397 PRO PRO A . n A 1 398 LEU 398 398 398 LEU LEU A . n A 1 399 VAL 399 399 399 VAL VAL A . n A 1 400 ARG 400 400 400 ARG ARG A . n A 1 401 VAL 401 401 401 VAL VAL A . n A 1 402 LEU 402 402 402 LEU LEU A . n A 1 403 VAL 403 403 403 VAL VAL A . n A 1 404 ASN 404 404 404 ASN ASN A . n A 1 405 ASP 405 405 405 ASP ASP A . n A 1 406 ARG 406 406 406 ARG ARG A . n A 1 407 VAL 407 407 407 VAL VAL A . n A 1 408 VAL 408 408 408 VAL VAL A . n A 1 409 PRO 409 409 409 PRO PRO A . n A 1 410 LEU 410 410 410 LEU LEU A . n A 1 411 HIS 411 411 411 HIS HIS A . n A 1 412 GLY 412 412 412 GLY GLY A . n A 1 413 CYS 413 413 413 CYS CYS A . n A 1 414 PRO 414 414 414 PRO PRO A . n A 1 415 VAL 415 415 415 VAL VAL A . n A 1 416 ASP 416 416 416 ASP ASP A . n A 1 417 ALA 417 417 417 ALA ALA A . n A 1 418 LEU 418 418 418 LEU LEU A . n A 1 419 GLY 419 419 419 GLY GLY A . n A 1 420 ARG 420 420 420 ARG ARG A . n A 1 421 CYS 421 421 421 CYS CYS A . n A 1 422 THR 422 422 422 THR THR A . n A 1 423 ARG 423 423 423 ARG ARG A . n A 1 424 ASP 424 424 424 ASP ASP A . n A 1 425 SER 425 425 425 SER SER A . n A 1 426 PHE 426 426 426 PHE PHE A . n A 1 427 VAL 427 427 427 VAL VAL A . n A 1 428 ARG 428 428 428 ARG ARG A . n A 1 429 GLY 429 429 429 GLY GLY A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 SER 431 431 431 SER SER A . n A 1 432 PHE 432 432 432 PHE PHE A . n A 1 433 ALA 433 433 433 ALA ALA A . n A 1 434 ARG 434 434 434 ARG ARG A . n A 1 435 SER 435 435 435 SER SER A . n A 1 436 GLY 436 436 436 GLY GLY A . n A 1 437 GLY 437 437 437 GLY GLY A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 TRP 439 439 439 TRP TRP A . n A 1 440 ALA 440 440 440 ALA ALA A . n A 1 441 GLU 441 441 441 GLU GLU A . n A 1 442 CYS 442 442 442 CYS CYS A . n A 1 443 PHE 443 443 443 PHE PHE A . n A 1 444 ALA 444 444 444 ALA ALA A . n B 1 1 ALA 1 1 ? ? ? B . n B 1 2 SER 2 2 ? ? ? B . n B 1 3 ARG 3 3 ? ? ? B . n B 1 4 ASN 4 4 ? ? ? B . n B 1 5 GLN 5 5 ? ? ? B . n B 1 6 SER 6 6 ? ? ? B . n B 1 7 SER 7 7 7 SER SER B . n B 1 8 CYS 8 8 8 CYS CYS B . n B 1 9 ASP 9 9 9 ASP ASP B . n B 1 10 THR 10 10 10 THR THR B . n B 1 11 VAL 11 11 11 VAL VAL B . n B 1 12 ASP 12 12 12 ASP ASP B . n B 1 13 GLN 13 13 13 GLN GLN B . n B 1 14 GLY 14 14 14 GLY GLY B . n B 1 15 TYR 15 15 15 TYR TYR B . n B 1 16 GLN 16 16 16 GLN GLN B . n B 1 17 CYS 17 17 17 CYS CYS B . n B 1 18 PHE 18 18 18 PHE PHE B . n B 1 19 SER 19 19 19 SER SER B . n B 1 20 GLU 20 20 20 GLU GLU B . n B 1 21 THR 21 21 21 THR THR B . n B 1 22 SER 22 22 22 SER SER B . n B 1 23 HIS 23 23 23 HIS HIS B . n B 1 24 LEU 24 24 24 LEU LEU B . n B 1 25 TRP 25 25 25 TRP TRP B . n B 1 26 GLY 26 26 26 GLY GLY B . n B 1 27 GLN 27 27 27 GLN GLN B . n B 1 28 TYR 28 28 28 TYR TYR B . n B 1 29 ALA 29 29 29 ALA ALA B . n B 1 30 PRO 30 30 30 PRO PRO B . n B 1 31 PHE 31 31 31 PHE PHE B . n B 1 32 PHE 32 32 32 PHE PHE B . n B 1 33 SER 33 33 33 SER SER B . n B 1 34 LEU 34 34 34 LEU LEU B . n B 1 35 ALA 35 35 35 ALA ALA B . n B 1 36 ASN 36 36 36 ASN ASN B . n B 1 37 GLU 37 37 37 GLU GLU B . n B 1 38 SER 38 38 38 SER SER B . n B 1 39 VAL 39 39 39 VAL VAL B . n B 1 40 ILE 40 40 40 ILE ILE B . n B 1 41 SER 41 41 41 SER SER B . n B 1 42 PRO 42 42 42 PRO PRO B . n B 1 43 GLU 43 43 43 GLU GLU B . n B 1 44 VAL 44 44 44 VAL VAL B . n B 1 45 PRO 45 45 45 PRO PRO B . n B 1 46 ALA 46 46 46 ALA ALA B . n B 1 47 GLY 47 47 47 GLY GLY B . n B 1 48 CYS 48 48 48 CYS CYS B . n B 1 49 ARG 49 49 49 ARG ARG B . n B 1 50 VAL 50 50 50 VAL VAL B . n B 1 51 THR 51 51 51 THR THR B . n B 1 52 PHE 52 52 52 PHE PHE B . n B 1 53 ALA 53 53 53 ALA ALA B . n B 1 54 GLN 54 54 54 GLN GLN B . n B 1 55 VAL 55 55 55 VAL VAL B . n B 1 56 LEU 56 56 56 LEU LEU B . n B 1 57 SER 57 57 57 SER SER B . n B 1 58 ARG 58 58 58 ARG ARG B . n B 1 59 HIS 59 59 59 HIS HIS B . n B 1 60 GLY 60 60 60 GLY GLY B . n B 1 61 ALA 61 61 61 ALA ALA B . n B 1 62 ARG 62 62 62 ARG ARG B . n B 1 63 TYR 63 63 63 TYR TYR B . n B 1 64 PRO 64 64 64 PRO PRO B . n B 1 65 THR 65 65 65 THR THR B . n B 1 66 ASP 66 66 66 ASP ASP B . n B 1 67 SER 67 67 67 SER SER B . n B 1 68 LYS 68 68 68 LYS LYS B . n B 1 69 GLY 69 69 69 GLY GLY B . n B 1 70 LYS 70 70 70 LYS LYS B . n B 1 71 LYS 71 71 71 LYS LYS B . n B 1 72 TYR 72 72 72 TYR TYR B . n B 1 73 SER 73 73 73 SER SER B . n B 1 74 ALA 74 74 74 ALA ALA B . n B 1 75 LEU 75 75 75 LEU LEU B . n B 1 76 ILE 76 76 76 ILE ILE B . n B 1 77 GLU 77 77 77 GLU GLU B . n B 1 78 GLU 78 78 78 GLU GLU B . n B 1 79 ILE 79 79 79 ILE ILE B . n B 1 80 GLN 80 80 80 GLN GLN B . n B 1 81 GLN 81 81 81 GLN GLN B . n B 1 82 ASN 82 82 82 ASN ASN B . n B 1 83 ALA 83 83 83 ALA ALA B . n B 1 84 THR 84 84 84 THR THR B . n B 1 85 THR 85 85 85 THR THR B . n B 1 86 PHE 86 86 86 PHE PHE B . n B 1 87 ASP 87 87 87 ASP ASP B . n B 1 88 GLY 88 88 88 GLY GLY B . n B 1 89 LYS 89 89 89 LYS LYS B . n B 1 90 TYR 90 90 90 TYR TYR B . n B 1 91 ALA 91 91 91 ALA ALA B . n B 1 92 PHE 92 92 92 PHE PHE B . n B 1 93 LEU 93 93 93 LEU LEU B . n B 1 94 LYS 94 94 94 LYS LYS B . n B 1 95 THR 95 95 95 THR THR B . n B 1 96 TYR 96 96 96 TYR TYR B . n B 1 97 ASN 97 97 97 ASN ASN B . n B 1 98 TYR 98 98 98 TYR TYR B . n B 1 99 SER 99 99 99 SER SER B . n B 1 100 LEU 100 100 100 LEU LEU B . n B 1 101 GLY 101 101 101 GLY GLY B . n B 1 102 ALA 102 102 102 ALA ALA B . n B 1 103 ASP 103 103 103 ASP ASP B . n B 1 104 ASP 104 104 104 ASP ASP B . n B 1 105 LEU 105 105 105 LEU LEU B . n B 1 106 THR 106 106 106 THR THR B . n B 1 107 PRO 107 107 107 PRO PRO B . n B 1 108 PHE 108 108 108 PHE PHE B . n B 1 109 GLY 109 109 109 GLY GLY B . n B 1 110 GLU 110 110 110 GLU GLU B . n B 1 111 GLN 111 111 111 GLN GLN B . n B 1 112 GLU 112 112 112 GLU GLU B . n B 1 113 LEU 113 113 113 LEU LEU B . n B 1 114 VAL 114 114 114 VAL VAL B . n B 1 115 ASN 115 115 115 ASN ASN B . n B 1 116 SER 116 116 116 SER SER B . n B 1 117 GLY 117 117 117 GLY GLY B . n B 1 118 ILE 118 118 118 ILE ILE B . n B 1 119 LYS 119 119 119 LYS LYS B . n B 1 120 PHE 120 120 120 PHE PHE B . n B 1 121 TYR 121 121 121 TYR TYR B . n B 1 122 GLN 122 122 122 GLN GLN B . n B 1 123 ARG 123 123 123 ARG ARG B . n B 1 124 TYR 124 124 124 TYR TYR B . n B 1 125 GLU 125 125 125 GLU GLU B . n B 1 126 SER 126 126 126 SER SER B . n B 1 127 LEU 127 127 127 LEU LEU B . n B 1 128 THR 128 128 128 THR THR B . n B 1 129 ARG 129 129 129 ARG ARG B . n B 1 130 ASN 130 130 130 ASN ASN B . n B 1 131 ILE 131 131 131 ILE ILE B . n B 1 132 VAL 132 132 132 VAL VAL B . n B 1 133 PRO 133 133 133 PRO PRO B . n B 1 134 PHE 134 134 134 PHE PHE B . n B 1 135 ILE 135 135 135 ILE ILE B . n B 1 136 ARG 136 136 136 ARG ARG B . n B 1 137 SER 137 137 137 SER SER B . n B 1 138 SER 138 138 138 SER SER B . n B 1 139 GLY 139 139 139 GLY GLY B . n B 1 140 SER 140 140 140 SER SER B . n B 1 141 SER 141 141 141 SER SER B . n B 1 142 ARG 142 142 142 ARG ARG B . n B 1 143 VAL 143 143 143 VAL VAL B . n B 1 144 ILE 144 144 144 ILE ILE B . n B 1 145 ALA 145 145 145 ALA ALA B . n B 1 146 SER 146 146 146 SER SER B . n B 1 147 GLY 147 147 147 GLY GLY B . n B 1 148 LYS 148 148 148 LYS LYS B . n B 1 149 LYS 149 149 149 LYS LYS B . n B 1 150 PHE 150 150 150 PHE PHE B . n B 1 151 ILE 151 151 151 ILE ILE B . n B 1 152 GLU 152 152 152 GLU GLU B . n B 1 153 GLY 153 153 153 GLY GLY B . n B 1 154 PHE 154 154 154 PHE PHE B . n B 1 155 GLN 155 155 155 GLN GLN B . n B 1 156 SER 156 156 156 SER SER B . n B 1 157 THR 157 157 157 THR THR B . n B 1 158 LYS 158 158 158 LYS LYS B . n B 1 159 LEU 159 159 159 LEU LEU B . n B 1 160 LYS 160 160 160 LYS LYS B . n B 1 161 ASP 161 161 161 ASP ASP B . n B 1 162 PRO 162 162 162 PRO PRO B . n B 1 163 ARG 163 163 163 ARG ARG B . n B 1 164 ALA 164 164 164 ALA ALA B . n B 1 165 GLN 165 165 165 GLN GLN B . n B 1 166 PRO 166 166 166 PRO PRO B . n B 1 167 GLY 167 167 167 GLY GLY B . n B 1 168 GLN 168 168 168 GLN GLN B . n B 1 169 SER 169 169 169 SER SER B . n B 1 170 SER 170 170 170 SER SER B . n B 1 171 PRO 171 171 171 PRO PRO B . n B 1 172 LYS 172 172 172 LYS LYS B . n B 1 173 ILE 173 173 173 ILE ILE B . n B 1 174 ASP 174 174 174 ASP ASP B . n B 1 175 VAL 175 175 175 VAL VAL B . n B 1 176 VAL 176 176 176 VAL VAL B . n B 1 177 ILE 177 177 177 ILE ILE B . n B 1 178 SER 178 178 178 SER SER B . n B 1 179 GLU 179 179 179 GLU GLU B . n B 1 180 ALA 180 180 180 ALA ALA B . n B 1 181 SER 181 181 181 SER SER B . n B 1 182 SER 182 182 182 SER SER B . n B 1 183 SER 183 183 183 SER SER B . n B 1 184 ASN 184 184 184 ASN ASN B . n B 1 185 ASN 185 185 185 ASN ASN B . n B 1 186 THR 186 186 186 THR THR B . n B 1 187 LEU 187 187 187 LEU LEU B . n B 1 188 ASP 188 188 188 ASP ASP B . n B 1 189 PRO 189 189 189 PRO PRO B . n B 1 190 GLY 190 190 190 GLY GLY B . n B 1 191 THR 191 191 191 THR THR B . n B 1 192 CYS 192 192 192 CYS CYS B . n B 1 193 THR 193 193 193 THR THR B . n B 1 194 VAL 194 194 194 VAL VAL B . n B 1 195 PHE 195 195 195 PHE PHE B . n B 1 196 GLU 196 196 196 GLU GLU B . n B 1 197 ASP 197 197 197 ASP ASP B . n B 1 198 SER 198 198 198 SER SER B . n B 1 199 GLU 199 199 199 GLU GLU B . n B 1 200 LEU 200 200 200 LEU LEU B . n B 1 201 ALA 201 201 201 ALA ALA B . n B 1 202 ASP 202 202 202 ASP ASP B . n B 1 203 THR 203 203 203 THR THR B . n B 1 204 VAL 204 204 204 VAL VAL B . n B 1 205 GLU 205 205 205 GLU GLU B . n B 1 206 ALA 206 206 206 ALA ALA B . n B 1 207 ASN 207 207 207 ASN ASN B . n B 1 208 PHE 208 208 208 PHE PHE B . n B 1 209 THR 209 209 209 THR THR B . n B 1 210 ALA 210 210 210 ALA ALA B . n B 1 211 THR 211 211 211 THR THR B . n B 1 212 PHE 212 212 212 PHE PHE B . n B 1 213 VAL 213 213 213 VAL VAL B . n B 1 214 PRO 214 214 214 PRO PRO B . n B 1 215 SER 215 215 215 SER SER B . n B 1 216 ILE 216 216 216 ILE ILE B . n B 1 217 ARG 217 217 217 ARG ARG B . n B 1 218 GLN 218 218 218 GLN GLN B . n B 1 219 ARG 219 219 219 ARG ARG B . n B 1 220 LEU 220 220 220 LEU LEU B . n B 1 221 GLU 221 221 221 GLU GLU B . n B 1 222 ASN 222 222 222 ASN ASN B . n B 1 223 ASP 223 223 223 ASP ASP B . n B 1 224 LEU 224 224 224 LEU LEU B . n B 1 225 SER 225 225 225 SER SER B . n B 1 226 GLY 226 226 226 GLY GLY B . n B 1 227 VAL 227 227 227 VAL VAL B . n B 1 228 THR 228 228 228 THR THR B . n B 1 229 LEU 229 229 229 LEU LEU B . n B 1 230 THR 230 230 230 THR THR B . n B 1 231 ASP 231 231 231 ASP ASP B . n B 1 232 THR 232 232 232 THR THR B . n B 1 233 GLU 233 233 233 GLU GLU B . n B 1 234 VAL 234 234 234 VAL VAL B . n B 1 235 THR 235 235 235 THR THR B . n B 1 236 TYR 236 236 236 TYR TYR B . n B 1 237 LEU 237 237 237 LEU LEU B . n B 1 238 MET 238 238 238 MET MET B . n B 1 239 ASP 239 239 239 ASP ASP B . n B 1 240 MET 240 240 240 MET MET B . n B 1 241 CYS 241 241 241 CYS CYS B . n B 1 242 SER 242 242 242 SER SER B . n B 1 243 PHE 243 243 243 PHE PHE B . n B 1 244 ASP 244 244 244 ASP ASP B . n B 1 245 THR 245 245 245 THR THR B . n B 1 246 ILE 246 246 246 ILE ILE B . n B 1 247 SER 247 247 247 SER SER B . n B 1 248 THR 248 248 248 THR THR B . n B 1 249 SER 249 249 249 SER SER B . n B 1 250 THR 250 250 250 THR THR B . n B 1 251 VAL 251 251 251 VAL VAL B . n B 1 252 ASP 252 252 252 ASP ASP B . n B 1 253 THR 253 253 253 THR THR B . n B 1 254 LYS 254 254 254 LYS LYS B . n B 1 255 LEU 255 255 255 LEU LEU B . n B 1 256 SER 256 256 256 SER SER B . n B 1 257 PRO 257 257 257 PRO PRO B . n B 1 258 PHE 258 258 258 PHE PHE B . n B 1 259 CYS 259 259 259 CYS CYS B . n B 1 260 ASP 260 260 260 ASP ASP B . n B 1 261 LEU 261 261 261 LEU LEU B . n B 1 262 PHE 262 262 262 PHE PHE B . n B 1 263 THR 263 263 263 THR THR B . n B 1 264 HIS 264 264 264 HIS HIS B . n B 1 265 ASP 265 265 265 ASP ASP B . n B 1 266 GLU 266 266 266 GLU GLU B . n B 1 267 TRP 267 267 267 TRP TRP B . n B 1 268 ILE 268 268 268 ILE ILE B . n B 1 269 ASN 269 269 269 ASN ASN B . n B 1 270 TYR 270 270 270 TYR TYR B . n B 1 271 ASP 271 271 271 ASP ASP B . n B 1 272 TYR 272 272 272 TYR TYR B . n B 1 273 LEU 273 273 273 LEU LEU B . n B 1 274 GLN 274 274 274 GLN GLN B . n B 1 275 SER 275 275 275 SER SER B . n B 1 276 LEU 276 276 276 LEU LEU B . n B 1 277 LYS 277 277 277 LYS LYS B . n B 1 278 LYS 278 278 278 LYS LYS B . n B 1 279 TYR 279 279 279 TYR TYR B . n B 1 280 TYR 280 280 280 TYR TYR B . n B 1 281 GLY 281 281 281 GLY GLY B . n B 1 282 HIS 282 282 282 HIS HIS B . n B 1 283 GLY 283 283 283 GLY GLY B . n B 1 284 ALA 284 284 284 ALA ALA B . n B 1 285 GLY 285 285 285 GLY GLY B . n B 1 286 ASN 286 286 286 ASN ASN B . n B 1 287 PRO 287 287 287 PRO PRO B . n B 1 288 LEU 288 288 288 LEU LEU B . n B 1 289 GLY 289 289 289 GLY GLY B . n B 1 290 PRO 290 290 290 PRO PRO B . n B 1 291 THR 291 291 291 THR THR B . n B 1 292 GLN 292 292 292 GLN GLN B . n B 1 293 GLY 293 293 293 GLY GLY B . n B 1 294 VAL 294 294 294 VAL VAL B . n B 1 295 GLY 295 295 295 GLY GLY B . n B 1 296 TYR 296 296 296 TYR TYR B . n B 1 297 ALA 297 297 297 ALA ALA B . n B 1 298 ASN 298 298 298 ASN ASN B . n B 1 299 GLU 299 299 299 GLU GLU B . n B 1 300 LEU 300 300 300 LEU LEU B . n B 1 301 ILE 301 301 301 ILE ILE B . n B 1 302 ALA 302 302 302 ALA ALA B . n B 1 303 ARG 303 303 303 ARG ARG B . n B 1 304 LEU 304 304 304 LEU LEU B . n B 1 305 THR 305 305 305 THR THR B . n B 1 306 HIS 306 306 306 HIS HIS B . n B 1 307 SER 307 307 307 SER SER B . n B 1 308 PRO 308 308 308 PRO PRO B . n B 1 309 VAL 309 309 309 VAL VAL B . n B 1 310 HIS 310 310 310 HIS HIS B . n B 1 311 ASP 311 311 311 ASP ASP B . n B 1 312 ASP 312 312 312 ASP ASP B . n B 1 313 THR 313 313 313 THR THR B . n B 1 314 SER 314 314 314 SER SER B . n B 1 315 SER 315 315 315 SER SER B . n B 1 316 ASN 316 316 316 ASN ASN B . n B 1 317 HIS 317 317 317 HIS HIS B . n B 1 318 THR 318 318 318 THR THR B . n B 1 319 LEU 319 319 319 LEU LEU B . n B 1 320 ASP 320 320 320 ASP ASP B . n B 1 321 SER 321 321 321 SER SER B . n B 1 322 SER 322 322 322 SER SER B . n B 1 323 PRO 323 323 323 PRO PRO B . n B 1 324 ALA 324 324 324 ALA ALA B . n B 1 325 THR 325 325 325 THR THR B . n B 1 326 PHE 326 326 326 PHE PHE B . n B 1 327 PRO 327 327 327 PRO PRO B . n B 1 328 LEU 328 328 328 LEU LEU B . n B 1 329 ASN 329 329 329 ASN ASN B . n B 1 330 SER 330 330 330 SER SER B . n B 1 331 THR 331 331 331 THR THR B . n B 1 332 LEU 332 332 332 LEU LEU B . n B 1 333 TYR 333 333 333 TYR TYR B . n B 1 334 ALA 334 334 334 ALA ALA B . n B 1 335 ASP 335 335 335 ASP ASP B . n B 1 336 PHE 336 336 336 PHE PHE B . n B 1 337 SER 337 337 337 SER SER B . n B 1 338 HIS 338 338 338 HIS HIS B . n B 1 339 ASP 339 339 339 ASP ASP B . n B 1 340 ASN 340 340 340 ASN ASN B . n B 1 341 GLY 341 341 341 GLY GLY B . n B 1 342 ILE 342 342 342 ILE ILE B . n B 1 343 ILE 343 343 343 ILE ILE B . n B 1 344 SER 344 344 344 SER SER B . n B 1 345 ILE 345 345 345 ILE ILE B . n B 1 346 LEU 346 346 346 LEU LEU B . n B 1 347 PHE 347 347 347 PHE PHE B . n B 1 348 ALA 348 348 348 ALA ALA B . n B 1 349 LEU 349 349 349 LEU LEU B . n B 1 350 GLY 350 350 350 GLY GLY B . n B 1 351 LEU 351 351 351 LEU LEU B . n B 1 352 TYR 352 352 352 TYR TYR B . n B 1 353 ASN 353 353 353 ASN ASN B . n B 1 354 GLY 354 354 354 GLY GLY B . n B 1 355 THR 355 355 355 THR THR B . n B 1 356 LYS 356 356 356 LYS LYS B . n B 1 357 PRO 357 357 357 PRO PRO B . n B 1 358 LEU 358 358 358 LEU LEU B . n B 1 359 SER 359 359 359 SER SER B . n B 1 360 THR 360 360 360 THR THR B . n B 1 361 THR 361 361 361 THR THR B . n B 1 362 THR 362 362 362 THR THR B . n B 1 363 VAL 363 363 363 VAL VAL B . n B 1 364 GLU 364 364 364 GLU GLU B . n B 1 365 ASN 365 365 365 ASN ASN B . n B 1 366 ILE 366 366 366 ILE ILE B . n B 1 367 THR 367 367 367 THR THR B . n B 1 368 GLN 368 368 368 GLN GLN B . n B 1 369 THR 369 369 369 THR THR B . n B 1 370 ASP 370 370 370 ASP ASP B . n B 1 371 GLY 371 371 371 GLY GLY B . n B 1 372 PHE 372 372 372 PHE PHE B . n B 1 373 SER 373 373 373 SER SER B . n B 1 374 SER 374 374 374 SER SER B . n B 1 375 ALA 375 375 375 ALA ALA B . n B 1 376 TRP 376 376 376 TRP TRP B . n B 1 377 THR 377 377 377 THR THR B . n B 1 378 VAL 378 378 378 VAL VAL B . n B 1 379 PRO 379 379 379 PRO PRO B . n B 1 380 PHE 380 380 380 PHE PHE B . n B 1 381 ALA 381 381 381 ALA ALA B . n B 1 382 SER 382 382 382 SER SER B . n B 1 383 ARG 383 383 383 ARG ARG B . n B 1 384 LEU 384 384 384 LEU LEU B . n B 1 385 TYR 385 385 385 TYR TYR B . n B 1 386 VAL 386 386 386 VAL VAL B . n B 1 387 GLU 387 387 387 GLU GLU B . n B 1 388 MET 388 388 388 MET MET B . n B 1 389 MET 389 389 389 MET MET B . n B 1 390 GLN 390 390 390 GLN GLN B . n B 1 391 CYS 391 391 391 CYS CYS B . n B 1 392 GLN 392 392 392 GLN GLN B . n B 1 393 ALA 393 393 393 ALA ALA B . n B 1 394 GLU 394 394 394 GLU GLU B . n B 1 395 GLN 395 395 395 GLN GLN B . n B 1 396 GLU 396 396 396 GLU GLU B . n B 1 397 PRO 397 397 397 PRO PRO B . n B 1 398 LEU 398 398 398 LEU LEU B . n B 1 399 VAL 399 399 399 VAL VAL B . n B 1 400 ARG 400 400 400 ARG ARG B . n B 1 401 VAL 401 401 401 VAL VAL B . n B 1 402 LEU 402 402 402 LEU LEU B . n B 1 403 VAL 403 403 403 VAL VAL B . n B 1 404 ASN 404 404 404 ASN ASN B . n B 1 405 ASP 405 405 405 ASP ASP B . n B 1 406 ARG 406 406 406 ARG ARG B . n B 1 407 VAL 407 407 407 VAL VAL B . n B 1 408 VAL 408 408 408 VAL VAL B . n B 1 409 PRO 409 409 409 PRO PRO B . n B 1 410 LEU 410 410 410 LEU LEU B . n B 1 411 HIS 411 411 411 HIS HIS B . n B 1 412 GLY 412 412 412 GLY GLY B . n B 1 413 CYS 413 413 413 CYS CYS B . n B 1 414 PRO 414 414 414 PRO PRO B . n B 1 415 VAL 415 415 415 VAL VAL B . n B 1 416 ASP 416 416 416 ASP ASP B . n B 1 417 ALA 417 417 417 ALA ALA B . n B 1 418 LEU 418 418 418 LEU LEU B . n B 1 419 GLY 419 419 419 GLY GLY B . n B 1 420 ARG 420 420 420 ARG ARG B . n B 1 421 CYS 421 421 421 CYS CYS B . n B 1 422 THR 422 422 422 THR THR B . n B 1 423 ARG 423 423 423 ARG ARG B . n B 1 424 ASP 424 424 424 ASP ASP B . n B 1 425 SER 425 425 425 SER SER B . n B 1 426 PHE 426 426 426 PHE PHE B . n B 1 427 VAL 427 427 427 VAL VAL B . n B 1 428 ARG 428 428 428 ARG ARG B . n B 1 429 GLY 429 429 429 GLY GLY B . n B 1 430 LEU 430 430 430 LEU LEU B . n B 1 431 SER 431 431 431 SER SER B . n B 1 432 PHE 432 432 432 PHE PHE B . n B 1 433 ALA 433 433 433 ALA ALA B . n B 1 434 ARG 434 434 434 ARG ARG B . n B 1 435 SER 435 435 435 SER SER B . n B 1 436 GLY 436 436 436 GLY GLY B . n B 1 437 GLY 437 437 437 GLY GLY B . n B 1 438 ASP 438 438 438 ASP ASP B . n B 1 439 TRP 439 439 439 TRP TRP B . n B 1 440 ALA 440 440 440 ALA ALA B . n B 1 441 GLU 441 441 441 GLU GLU B . n B 1 442 CYS 442 442 442 CYS CYS B . n B 1 443 PHE 443 443 443 PHE PHE B . n B 1 444 ALA 444 444 444 ALA ALA B . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 82 A ASN 82 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 316 A ASN 316 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 353 A ASN 353 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 82 B ASN 82 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 316 B ASN 316 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 353 B ASN 353 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,I 2 1 B,F,G,H,J # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-06-30 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal Blu-Ice 'data collection' . ? 1 MOLREP phasing . ? 2 REFMAC refinement 5.5.0102 ? 3 MOSFLM 'data reduction' . ? 4 SCALA 'data scaling' . ? 5 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 ND2 A ASN 97 ? ? O A HOH 521 ? ? 2.11 2 1 ND2 A ASN 353 ? ? O5 A NAG 1003 ? ? 2.13 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 CB _pdbx_validate_rmsd_angle.auth_asym_id_1 B _pdbx_validate_rmsd_angle.auth_comp_id_1 ASP _pdbx_validate_rmsd_angle.auth_seq_id_1 239 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CG _pdbx_validate_rmsd_angle.auth_asym_id_2 B _pdbx_validate_rmsd_angle.auth_comp_id_2 ASP _pdbx_validate_rmsd_angle.auth_seq_id_2 239 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 OD1 _pdbx_validate_rmsd_angle.auth_asym_id_3 B _pdbx_validate_rmsd_angle.auth_comp_id_3 ASP _pdbx_validate_rmsd_angle.auth_seq_id_3 239 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 123.90 _pdbx_validate_rmsd_angle.angle_target_value 118.30 _pdbx_validate_rmsd_angle.angle_deviation 5.60 _pdbx_validate_rmsd_angle.angle_standard_deviation 0.90 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PHE A 31 ? ? -38.93 131.33 2 1 SER A 67 ? ? -37.27 -70.94 3 1 LEU A 100 ? ? -36.22 146.05 4 1 ASP A 103 ? ? 71.54 -35.37 5 1 ASN A 130 ? ? -146.32 14.05 6 1 ASP A 188 ? ? -172.53 76.65 7 1 PHE A 212 ? ? -145.94 -29.36 8 1 LEU A 224 ? ? -111.10 79.22 9 1 THR A 313 ? ? -95.62 -91.98 10 1 THR A 377 ? ? -122.65 -57.03 11 1 VAL A 378 ? ? -117.77 57.11 12 1 ASP A 405 ? ? 85.69 6.03 13 1 PRO A 414 ? ? -69.47 85.53 14 1 LEU A 430 ? ? -94.77 40.36 15 1 PHE B 31 ? ? -36.05 130.17 16 1 TYR B 96 ? ? -39.66 129.58 17 1 LEU B 100 ? ? -39.70 146.54 18 1 ASP B 103 ? ? 73.53 -36.17 19 1 ASN B 130 ? ? -147.14 13.18 20 1 ASN B 184 ? ? -66.54 97.58 21 1 ASP B 188 ? ? -170.45 77.99 22 1 PHE B 212 ? ? -143.92 -29.51 23 1 LEU B 224 ? ? -112.51 78.84 24 1 THR B 313 ? ? -97.96 -89.20 25 1 THR B 377 ? ? -120.80 -54.41 26 1 VAL B 378 ? ? -118.40 56.69 27 1 ASP B 405 ? ? 86.49 6.38 28 1 PRO B 414 ? ? -69.14 87.56 29 1 LEU B 430 ? ? -94.03 42.05 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A GLN 392 ? CG ? A GLN 392 CG 2 1 Y 1 A GLN 392 ? CD ? A GLN 392 CD 3 1 Y 1 A GLN 392 ? OE1 ? A GLN 392 OE1 4 1 Y 1 A GLN 392 ? NE2 ? A GLN 392 NE2 5 1 Y 1 A GLN 395 ? CG ? A GLN 395 CG 6 1 Y 1 A GLN 395 ? CD ? A GLN 395 CD 7 1 Y 1 A GLN 395 ? OE1 ? A GLN 395 OE1 8 1 Y 1 A GLN 395 ? NE2 ? A GLN 395 NE2 9 1 Y 1 B LYS 254 ? CG ? B LYS 254 CG 10 1 Y 1 B LYS 254 ? CD ? B LYS 254 CD 11 1 Y 1 B LYS 254 ? CE ? B LYS 254 CE 12 1 Y 1 B LYS 254 ? NZ ? B LYS 254 NZ 13 1 Y 1 B ASP 265 ? CG ? B ASP 265 CG 14 1 Y 1 B ASP 265 ? OD1 ? B ASP 265 OD1 15 1 Y 1 B ASP 265 ? OD2 ? B ASP 265 OD2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ALA 1 ? A ALA 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A ARG 3 ? A ARG 3 4 1 Y 1 A ASN 4 ? A ASN 4 5 1 Y 1 A GLN 5 ? A GLN 5 6 1 Y 1 A SER 6 ? A SER 6 7 1 Y 1 B ALA 1 ? B ALA 1 8 1 Y 1 B SER 2 ? B SER 2 9 1 Y 1 B ARG 3 ? B ARG 3 10 1 Y 1 B ASN 4 ? B ASN 4 11 1 Y 1 B GLN 5 ? B GLN 5 12 1 Y 1 B SER 6 ? B SER 6 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 1001 1001 NAG NAG A . D 2 NAG 1 1002 1002 NAG NAG A . E 2 NAG 1 1003 1003 NAG NAG A . F 2 NAG 1 1001 1001 NAG NAG B . G 2 NAG 1 1002 1002 NAG NAG B . H 2 NAG 1 1003 1003 NAG NAG B . I 3 HOH 1 445 2 HOH HOH A . I 3 HOH 2 446 3 HOH HOH A . I 3 HOH 3 447 5 HOH HOH A . I 3 HOH 4 448 8 HOH HOH A . I 3 HOH 5 449 9 HOH HOH A . I 3 HOH 6 450 10 HOH HOH A . I 3 HOH 7 451 12 HOH HOH A . I 3 HOH 8 452 15 HOH HOH A . I 3 HOH 9 453 18 HOH HOH A . I 3 HOH 10 454 20 HOH HOH A . I 3 HOH 11 455 22 HOH HOH A . I 3 HOH 12 456 26 HOH HOH A . I 3 HOH 13 457 27 HOH HOH A . I 3 HOH 14 458 28 HOH HOH A . I 3 HOH 15 459 32 HOH HOH A . I 3 HOH 16 460 33 HOH HOH A . I 3 HOH 17 461 37 HOH HOH A . I 3 HOH 18 462 39 HOH HOH A . I 3 HOH 19 463 41 HOH HOH A . I 3 HOH 20 464 43 HOH HOH A . I 3 HOH 21 465 44 HOH HOH A . I 3 HOH 22 466 47 HOH HOH A . I 3 HOH 23 467 48 HOH HOH A . I 3 HOH 24 468 51 HOH HOH A . I 3 HOH 25 469 55 HOH HOH A . I 3 HOH 26 470 56 HOH HOH A . I 3 HOH 27 471 59 HOH HOH A . I 3 HOH 28 472 60 HOH HOH A . I 3 HOH 29 473 64 HOH HOH A . I 3 HOH 30 474 66 HOH HOH A . I 3 HOH 31 475 67 HOH HOH A . I 3 HOH 32 476 68 HOH HOH A . I 3 HOH 33 477 71 HOH HOH A . I 3 HOH 34 478 72 HOH HOH A . I 3 HOH 35 479 74 HOH HOH A . I 3 HOH 36 480 77 HOH HOH A . I 3 HOH 37 481 81 HOH HOH A . I 3 HOH 38 482 83 HOH HOH A . I 3 HOH 39 483 87 HOH HOH A . I 3 HOH 40 484 88 HOH HOH A . I 3 HOH 41 485 89 HOH HOH A . I 3 HOH 42 486 90 HOH HOH A . I 3 HOH 43 487 94 HOH HOH A . I 3 HOH 44 488 96 HOH HOH A . I 3 HOH 45 489 97 HOH HOH A . I 3 HOH 46 490 98 HOH HOH A . I 3 HOH 47 491 100 HOH HOH A . I 3 HOH 48 492 101 HOH HOH A . I 3 HOH 49 493 102 HOH HOH A . I 3 HOH 50 494 103 HOH HOH A . I 3 HOH 51 495 104 HOH HOH A . I 3 HOH 52 496 105 HOH HOH A . I 3 HOH 53 497 106 HOH HOH A . I 3 HOH 54 498 107 HOH HOH A . I 3 HOH 55 499 108 HOH HOH A . I 3 HOH 56 500 111 HOH HOH A . I 3 HOH 57 501 113 HOH HOH A . I 3 HOH 58 502 115 HOH HOH A . I 3 HOH 59 503 119 HOH HOH A . I 3 HOH 60 504 120 HOH HOH A . I 3 HOH 61 505 121 HOH HOH A . I 3 HOH 62 506 122 HOH HOH A . I 3 HOH 63 507 123 HOH HOH A . I 3 HOH 64 508 124 HOH HOH A . I 3 HOH 65 509 125 HOH HOH A . I 3 HOH 66 510 127 HOH HOH A . I 3 HOH 67 511 128 HOH HOH A . I 3 HOH 68 512 129 HOH HOH A . I 3 HOH 69 513 130 HOH HOH A . I 3 HOH 70 514 132 HOH HOH A . I 3 HOH 71 515 133 HOH HOH A . I 3 HOH 72 516 136 HOH HOH A . I 3 HOH 73 517 138 HOH HOH A . I 3 HOH 74 518 140 HOH HOH A . I 3 HOH 75 519 141 HOH HOH A . I 3 HOH 76 520 143 HOH HOH A . I 3 HOH 77 521 144 HOH HOH A . I 3 HOH 78 522 146 HOH HOH A . I 3 HOH 79 523 147 HOH HOH A . I 3 HOH 80 524 148 HOH HOH A . I 3 HOH 81 525 149 HOH HOH A . I 3 HOH 82 526 150 HOH HOH A . I 3 HOH 83 527 152 HOH HOH A . I 3 HOH 84 528 155 HOH HOH A . I 3 HOH 85 529 157 HOH HOH A . I 3 HOH 86 530 161 HOH HOH A . I 3 HOH 87 531 162 HOH HOH A . I 3 HOH 88 532 167 HOH HOH A . I 3 HOH 89 533 168 HOH HOH A . I 3 HOH 90 534 170 HOH HOH A . I 3 HOH 91 535 174 HOH HOH A . I 3 HOH 92 536 175 HOH HOH A . I 3 HOH 93 537 177 HOH HOH A . I 3 HOH 94 538 180 HOH HOH A . I 3 HOH 95 539 181 HOH HOH A . I 3 HOH 96 540 182 HOH HOH A . I 3 HOH 97 541 183 HOH HOH A . I 3 HOH 98 542 184 HOH HOH A . I 3 HOH 99 543 185 HOH HOH A . I 3 HOH 100 544 187 HOH HOH A . I 3 HOH 101 545 192 HOH HOH A . I 3 HOH 102 546 194 HOH HOH A . I 3 HOH 103 547 197 HOH HOH A . I 3 HOH 104 548 198 HOH HOH A . I 3 HOH 105 549 199 HOH HOH A . I 3 HOH 106 550 200 HOH HOH A . I 3 HOH 107 551 201 HOH HOH A . I 3 HOH 108 552 203 HOH HOH A . I 3 HOH 109 553 204 HOH HOH A . I 3 HOH 110 554 205 HOH HOH A . I 3 HOH 111 555 207 HOH HOH A . I 3 HOH 112 556 208 HOH HOH A . I 3 HOH 113 557 209 HOH HOH A . I 3 HOH 114 558 210 HOH HOH A . I 3 HOH 115 559 215 HOH HOH A . I 3 HOH 116 560 220 HOH HOH A . I 3 HOH 117 561 221 HOH HOH A . I 3 HOH 118 562 225 HOH HOH A . I 3 HOH 119 563 228 HOH HOH A . I 3 HOH 120 564 229 HOH HOH A . I 3 HOH 121 565 230 HOH HOH A . I 3 HOH 122 566 231 HOH HOH A . I 3 HOH 123 567 232 HOH HOH A . I 3 HOH 124 568 237 HOH HOH A . I 3 HOH 125 569 238 HOH HOH A . I 3 HOH 126 570 240 HOH HOH A . I 3 HOH 127 571 242 HOH HOH A . I 3 HOH 128 572 243 HOH HOH A . I 3 HOH 129 573 244 HOH HOH A . I 3 HOH 130 574 245 HOH HOH A . I 3 HOH 131 575 246 HOH HOH A . I 3 HOH 132 576 248 HOH HOH A . I 3 HOH 133 577 249 HOH HOH A . I 3 HOH 134 578 251 HOH HOH A . I 3 HOH 135 579 252 HOH HOH A . I 3 HOH 136 580 253 HOH HOH A . I 3 HOH 137 581 254 HOH HOH A . I 3 HOH 138 582 256 HOH HOH A . I 3 HOH 139 583 259 HOH HOH A . I 3 HOH 140 584 261 HOH HOH A . I 3 HOH 141 585 262 HOH HOH A . I 3 HOH 142 586 263 HOH HOH A . I 3 HOH 143 587 265 HOH HOH A . I 3 HOH 144 588 267 HOH HOH A . I 3 HOH 145 589 269 HOH HOH A . I 3 HOH 146 590 273 HOH HOH A . I 3 HOH 147 591 274 HOH HOH A . I 3 HOH 148 592 278 HOH HOH A . I 3 HOH 149 593 280 HOH HOH A . I 3 HOH 150 594 281 HOH HOH A . I 3 HOH 151 595 283 HOH HOH A . I 3 HOH 152 596 286 HOH HOH A . I 3 HOH 153 597 289 HOH HOH A . I 3 HOH 154 598 290 HOH HOH A . I 3 HOH 155 599 292 HOH HOH A . I 3 HOH 156 600 297 HOH HOH A . I 3 HOH 157 601 298 HOH HOH A . I 3 HOH 158 602 299 HOH HOH A . I 3 HOH 159 603 300 HOH HOH A . I 3 HOH 160 604 301 HOH HOH A . I 3 HOH 161 605 302 HOH HOH A . I 3 HOH 162 606 304 HOH HOH A . I 3 HOH 163 607 306 HOH HOH A . I 3 HOH 164 608 307 HOH HOH A . I 3 HOH 165 609 311 HOH HOH A . I 3 HOH 166 610 312 HOH HOH A . I 3 HOH 167 611 315 HOH HOH A . I 3 HOH 168 612 316 HOH HOH A . I 3 HOH 169 613 317 HOH HOH A . J 3 HOH 1 445 1 HOH HOH B . J 3 HOH 2 446 4 HOH HOH B . J 3 HOH 3 447 6 HOH HOH B . J 3 HOH 4 448 7 HOH HOH B . J 3 HOH 5 449 11 HOH HOH B . J 3 HOH 6 450 13 HOH HOH B . J 3 HOH 7 451 14 HOH HOH B . J 3 HOH 8 452 16 HOH HOH B . J 3 HOH 9 453 17 HOH HOH B . J 3 HOH 10 454 19 HOH HOH B . J 3 HOH 11 455 21 HOH HOH B . J 3 HOH 12 456 23 HOH HOH B . J 3 HOH 13 457 24 HOH HOH B . J 3 HOH 14 458 25 HOH HOH B . J 3 HOH 15 459 29 HOH HOH B . J 3 HOH 16 460 30 HOH HOH B . J 3 HOH 17 461 31 HOH HOH B . J 3 HOH 18 462 34 HOH HOH B . J 3 HOH 19 463 35 HOH HOH B . J 3 HOH 20 464 36 HOH HOH B . J 3 HOH 21 465 38 HOH HOH B . J 3 HOH 22 466 40 HOH HOH B . J 3 HOH 23 467 42 HOH HOH B . J 3 HOH 24 468 45 HOH HOH B . J 3 HOH 25 469 46 HOH HOH B . J 3 HOH 26 470 49 HOH HOH B . J 3 HOH 27 471 50 HOH HOH B . J 3 HOH 28 472 52 HOH HOH B . J 3 HOH 29 473 53 HOH HOH B . J 3 HOH 30 474 54 HOH HOH B . J 3 HOH 31 475 57 HOH HOH B . J 3 HOH 32 476 58 HOH HOH B . J 3 HOH 33 477 61 HOH HOH B . J 3 HOH 34 478 62 HOH HOH B . J 3 HOH 35 479 63 HOH HOH B . J 3 HOH 36 480 65 HOH HOH B . J 3 HOH 37 481 69 HOH HOH B . J 3 HOH 38 482 70 HOH HOH B . J 3 HOH 39 483 73 HOH HOH B . J 3 HOH 40 484 75 HOH HOH B . J 3 HOH 41 485 76 HOH HOH B . J 3 HOH 42 486 78 HOH HOH B . J 3 HOH 43 487 79 HOH HOH B . J 3 HOH 44 488 80 HOH HOH B . J 3 HOH 45 489 82 HOH HOH B . J 3 HOH 46 490 84 HOH HOH B . J 3 HOH 47 491 85 HOH HOH B . J 3 HOH 48 492 86 HOH HOH B . J 3 HOH 49 493 91 HOH HOH B . J 3 HOH 50 494 92 HOH HOH B . J 3 HOH 51 495 93 HOH HOH B . J 3 HOH 52 496 95 HOH HOH B . J 3 HOH 53 497 99 HOH HOH B . J 3 HOH 54 498 109 HOH HOH B . J 3 HOH 55 499 110 HOH HOH B . J 3 HOH 56 500 112 HOH HOH B . J 3 HOH 57 501 114 HOH HOH B . J 3 HOH 58 502 116 HOH HOH B . J 3 HOH 59 503 117 HOH HOH B . J 3 HOH 60 504 118 HOH HOH B . J 3 HOH 61 505 126 HOH HOH B . J 3 HOH 62 506 131 HOH HOH B . J 3 HOH 63 507 134 HOH HOH B . J 3 HOH 64 508 135 HOH HOH B . J 3 HOH 65 509 137 HOH HOH B . J 3 HOH 66 510 139 HOH HOH B . J 3 HOH 67 511 142 HOH HOH B . J 3 HOH 68 512 145 HOH HOH B . J 3 HOH 69 513 151 HOH HOH B . J 3 HOH 70 514 153 HOH HOH B . J 3 HOH 71 515 154 HOH HOH B . J 3 HOH 72 516 156 HOH HOH B . J 3 HOH 73 517 158 HOH HOH B . J 3 HOH 74 518 159 HOH HOH B . J 3 HOH 75 519 160 HOH HOH B . J 3 HOH 76 520 163 HOH HOH B . J 3 HOH 77 521 164 HOH HOH B . J 3 HOH 78 522 165 HOH HOH B . J 3 HOH 79 523 166 HOH HOH B . J 3 HOH 80 524 169 HOH HOH B . J 3 HOH 81 525 171 HOH HOH B . J 3 HOH 82 526 172 HOH HOH B . J 3 HOH 83 527 173 HOH HOH B . J 3 HOH 84 528 176 HOH HOH B . J 3 HOH 85 529 178 HOH HOH B . J 3 HOH 86 530 179 HOH HOH B . J 3 HOH 87 531 186 HOH HOH B . J 3 HOH 88 532 188 HOH HOH B . J 3 HOH 89 533 189 HOH HOH B . J 3 HOH 90 534 190 HOH HOH B . J 3 HOH 91 535 191 HOH HOH B . J 3 HOH 92 536 193 HOH HOH B . J 3 HOH 93 537 195 HOH HOH B . J 3 HOH 94 538 196 HOH HOH B . J 3 HOH 95 539 202 HOH HOH B . J 3 HOH 96 540 206 HOH HOH B . J 3 HOH 97 541 211 HOH HOH B . J 3 HOH 98 542 212 HOH HOH B . J 3 HOH 99 543 213 HOH HOH B . J 3 HOH 100 544 214 HOH HOH B . J 3 HOH 101 545 216 HOH HOH B . J 3 HOH 102 546 217 HOH HOH B . J 3 HOH 103 547 218 HOH HOH B . J 3 HOH 104 548 219 HOH HOH B . J 3 HOH 105 549 222 HOH HOH B . J 3 HOH 106 550 223 HOH HOH B . J 3 HOH 107 551 224 HOH HOH B . J 3 HOH 108 552 227 HOH HOH B . J 3 HOH 109 553 233 HOH HOH B . J 3 HOH 110 554 234 HOH HOH B . J 3 HOH 111 555 235 HOH HOH B . J 3 HOH 112 556 236 HOH HOH B . J 3 HOH 113 557 239 HOH HOH B . J 3 HOH 114 558 241 HOH HOH B . J 3 HOH 115 559 247 HOH HOH B . J 3 HOH 116 560 250 HOH HOH B . J 3 HOH 117 561 255 HOH HOH B . J 3 HOH 118 562 257 HOH HOH B . J 3 HOH 119 563 258 HOH HOH B . J 3 HOH 120 564 260 HOH HOH B . J 3 HOH 121 565 264 HOH HOH B . J 3 HOH 122 566 266 HOH HOH B . J 3 HOH 123 567 268 HOH HOH B . J 3 HOH 124 568 270 HOH HOH B . J 3 HOH 125 569 271 HOH HOH B . J 3 HOH 126 570 272 HOH HOH B . J 3 HOH 127 571 275 HOH HOH B . J 3 HOH 128 572 276 HOH HOH B . J 3 HOH 129 573 277 HOH HOH B . J 3 HOH 130 574 279 HOH HOH B . J 3 HOH 131 575 282 HOH HOH B . J 3 HOH 132 576 284 HOH HOH B . J 3 HOH 133 577 285 HOH HOH B . J 3 HOH 134 578 287 HOH HOH B . J 3 HOH 135 579 288 HOH HOH B . J 3 HOH 136 580 291 HOH HOH B . J 3 HOH 137 581 293 HOH HOH B . J 3 HOH 138 582 294 HOH HOH B . J 3 HOH 139 583 295 HOH HOH B . J 3 HOH 140 584 296 HOH HOH B . J 3 HOH 141 585 303 HOH HOH B . J 3 HOH 142 586 305 HOH HOH B . J 3 HOH 143 587 308 HOH HOH B . J 3 HOH 144 588 309 HOH HOH B . J 3 HOH 145 589 310 HOH HOH B . J 3 HOH 146 590 313 HOH HOH B . J 3 HOH 147 591 314 HOH HOH B . #