data_3HII # _entry.id 3HII # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3HII RCSB RCSB053175 WWPDB D_1000053175 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3HI7 'The crystal structure of human diamine oxidase' unspecified PDB 3HIG 'Crystal structure of human diamine oxidase in complex with the inhibitor berenil' unspecified # _pdbx_database_status.entry_id 3HII _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.recvd_initial_deposition_date 2009-05-20 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'McGrath, A.P.' 1 'Guss, J.M.' 2 # _citation.id primary _citation.title 'Structure and inhibition of human diamine oxidase' _citation.journal_abbrev Biochemistry _citation.journal_volume 48 _citation.page_first 9810 _citation.page_last 9822 _citation.year 2009 _citation.journal_id_ASTM BICHAW _citation.country US _citation.journal_id_ISSN 0006-2960 _citation.journal_id_CSD 0033 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 19764817 _citation.pdbx_database_id_DOI 10.1021/bi9014192 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'McGrath, A.P.' 1 primary 'Hilmer, K.M.' 2 primary 'Collyer, C.A.' 3 primary 'Shepard, E.M.' 4 primary 'Elmore, B.O.' 5 primary 'Brown, D.E.' 6 primary 'Dooley, D.M.' 7 primary 'Guss, J.M.' 8 # _cell.entry_id 3HII _cell.length_a 92.455 _cell.length_b 94.690 _cell.length_c 196.279 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3HII _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Amiloride-sensitive amine oxidase' 83463.797 2 1.4.3.22 ? ? ? 2 non-polymer syn 'COPPER (II) ION' 63.546 2 ? ? ? ? 3 non-polymer syn 'CALCIUM ION' 40.078 4 ? ? ? ? 4 non-polymer syn GLYCEROL 92.094 1 ? ? ? ? 5 non-polymer syn '1,5-BIS(4-AMIDINOPHENOXY)PENTANE' 340.419 2 ? ? ? ? 6 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 12 ? ? ? ? 7 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 8 water nat water 18.015 916 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Diamine oxidase, DAO, Amiloride-binding protein, ABP, Histaminase, Kidney amine oxidase, KAO' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer yes _entity_poly.pdbx_seq_one_letter_code ;RSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAV IFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDV VVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVH FGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYN(TPQ)DYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLR HGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKY LLFTSPQENPWGHKRSYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWDPPVVFEQFLHN NENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDC SMPPPFSYNGTYRPV ; _entity_poly.pdbx_seq_one_letter_code_can ;RSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAV IFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDV VVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVH FGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTR LHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFT SPQENPWGHKRSYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWDPPVVFEQFLHNNENI ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPP PFSYNGTYRPV ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 PRO n 1 4 GLY n 1 5 THR n 1 6 LEU n 1 7 PRO n 1 8 ARG n 1 9 LYS n 1 10 ALA n 1 11 GLY n 1 12 VAL n 1 13 PHE n 1 14 SER n 1 15 ASP n 1 16 LEU n 1 17 SER n 1 18 ASN n 1 19 GLN n 1 20 GLU n 1 21 LEU n 1 22 LYS n 1 23 ALA n 1 24 VAL n 1 25 HIS n 1 26 SER n 1 27 PHE n 1 28 LEU n 1 29 TRP n 1 30 SER n 1 31 LYS n 1 32 LYS n 1 33 GLU n 1 34 LEU n 1 35 ARG n 1 36 LEU n 1 37 GLN n 1 38 PRO n 1 39 SER n 1 40 SER n 1 41 THR n 1 42 THR n 1 43 THR n 1 44 MET n 1 45 ALA n 1 46 LYS n 1 47 ASN n 1 48 THR n 1 49 VAL n 1 50 PHE n 1 51 LEU n 1 52 ILE n 1 53 GLU n 1 54 MET n 1 55 LEU n 1 56 LEU n 1 57 PRO n 1 58 LYS n 1 59 LYS n 1 60 TYR n 1 61 HIS n 1 62 VAL n 1 63 LEU n 1 64 ARG n 1 65 PHE n 1 66 LEU n 1 67 ASP n 1 68 LYS n 1 69 GLY n 1 70 GLU n 1 71 ARG n 1 72 HIS n 1 73 PRO n 1 74 VAL n 1 75 ARG n 1 76 GLU n 1 77 ALA n 1 78 ARG n 1 79 ALA n 1 80 VAL n 1 81 ILE n 1 82 PHE n 1 83 PHE n 1 84 GLY n 1 85 ASP n 1 86 GLN n 1 87 GLU n 1 88 HIS n 1 89 PRO n 1 90 ASN n 1 91 VAL n 1 92 THR n 1 93 GLU n 1 94 PHE n 1 95 ALA n 1 96 VAL n 1 97 GLY n 1 98 PRO n 1 99 LEU n 1 100 PRO n 1 101 GLY n 1 102 PRO n 1 103 CYS n 1 104 TYR n 1 105 MET n 1 106 ARG n 1 107 ALA n 1 108 LEU n 1 109 SER n 1 110 PRO n 1 111 ARG n 1 112 PRO n 1 113 GLY n 1 114 TYR n 1 115 GLN n 1 116 SER n 1 117 SER n 1 118 TRP n 1 119 ALA n 1 120 SER n 1 121 ARG n 1 122 PRO n 1 123 ILE n 1 124 SER n 1 125 THR n 1 126 ALA n 1 127 GLU n 1 128 TYR n 1 129 ALA n 1 130 LEU n 1 131 LEU n 1 132 TYR n 1 133 HIS n 1 134 THR n 1 135 LEU n 1 136 GLN n 1 137 GLU n 1 138 ALA n 1 139 THR n 1 140 LYS n 1 141 PRO n 1 142 LEU n 1 143 HIS n 1 144 GLN n 1 145 PHE n 1 146 PHE n 1 147 LEU n 1 148 ASN n 1 149 THR n 1 150 THR n 1 151 GLY n 1 152 PHE n 1 153 SER n 1 154 PHE n 1 155 GLN n 1 156 ASP n 1 157 CYS n 1 158 HIS n 1 159 ASP n 1 160 ARG n 1 161 CYS n 1 162 LEU n 1 163 ALA n 1 164 PHE n 1 165 THR n 1 166 ASP n 1 167 VAL n 1 168 ALA n 1 169 PRO n 1 170 ARG n 1 171 GLY n 1 172 VAL n 1 173 ALA n 1 174 SER n 1 175 GLY n 1 176 GLN n 1 177 ARG n 1 178 ARG n 1 179 SER n 1 180 TRP n 1 181 LEU n 1 182 ILE n 1 183 ILE n 1 184 GLN n 1 185 ARG n 1 186 TYR n 1 187 VAL n 1 188 GLU n 1 189 GLY n 1 190 TYR n 1 191 PHE n 1 192 LEU n 1 193 HIS n 1 194 PRO n 1 195 THR n 1 196 GLY n 1 197 LEU n 1 198 GLU n 1 199 LEU n 1 200 LEU n 1 201 VAL n 1 202 ASP n 1 203 HIS n 1 204 GLY n 1 205 SER n 1 206 THR n 1 207 ASP n 1 208 ALA n 1 209 GLY n 1 210 HIS n 1 211 TRP n 1 212 ALA n 1 213 VAL n 1 214 GLU n 1 215 GLN n 1 216 VAL n 1 217 TRP n 1 218 TYR n 1 219 ASN n 1 220 GLY n 1 221 LYS n 1 222 PHE n 1 223 TYR n 1 224 GLY n 1 225 SER n 1 226 PRO n 1 227 GLU n 1 228 GLU n 1 229 LEU n 1 230 ALA n 1 231 ARG n 1 232 LYS n 1 233 TYR n 1 234 ALA n 1 235 ASP n 1 236 GLY n 1 237 GLU n 1 238 VAL n 1 239 ASP n 1 240 VAL n 1 241 VAL n 1 242 VAL n 1 243 LEU n 1 244 GLU n 1 245 ASP n 1 246 PRO n 1 247 LEU n 1 248 PRO n 1 249 GLY n 1 250 GLY n 1 251 LYS n 1 252 GLY n 1 253 HIS n 1 254 ASP n 1 255 SER n 1 256 THR n 1 257 GLU n 1 258 GLU n 1 259 PRO n 1 260 PRO n 1 261 LEU n 1 262 PHE n 1 263 SER n 1 264 SER n 1 265 HIS n 1 266 LYS n 1 267 PRO n 1 268 ARG n 1 269 GLY n 1 270 ASP n 1 271 PHE n 1 272 PRO n 1 273 SER n 1 274 PRO n 1 275 ILE n 1 276 HIS n 1 277 VAL n 1 278 SER n 1 279 GLY n 1 280 PRO n 1 281 ARG n 1 282 LEU n 1 283 VAL n 1 284 GLN n 1 285 PRO n 1 286 HIS n 1 287 GLY n 1 288 PRO n 1 289 ARG n 1 290 PHE n 1 291 ARG n 1 292 LEU n 1 293 GLU n 1 294 GLY n 1 295 ASN n 1 296 ALA n 1 297 VAL n 1 298 LEU n 1 299 TYR n 1 300 GLY n 1 301 GLY n 1 302 TRP n 1 303 SER n 1 304 PHE n 1 305 ALA n 1 306 PHE n 1 307 ARG n 1 308 LEU n 1 309 ARG n 1 310 SER n 1 311 SER n 1 312 SER n 1 313 GLY n 1 314 LEU n 1 315 GLN n 1 316 VAL n 1 317 LEU n 1 318 ASN n 1 319 VAL n 1 320 HIS n 1 321 PHE n 1 322 GLY n 1 323 GLY n 1 324 GLU n 1 325 ARG n 1 326 ILE n 1 327 ALA n 1 328 TYR n 1 329 GLU n 1 330 VAL n 1 331 SER n 1 332 VAL n 1 333 GLN n 1 334 GLU n 1 335 ALA n 1 336 VAL n 1 337 ALA n 1 338 LEU n 1 339 TYR n 1 340 GLY n 1 341 GLY n 1 342 HIS n 1 343 THR n 1 344 PRO n 1 345 ALA n 1 346 GLY n 1 347 MET n 1 348 GLN n 1 349 THR n 1 350 LYS n 1 351 TYR n 1 352 LEU n 1 353 ASP n 1 354 VAL n 1 355 GLY n 1 356 TRP n 1 357 GLY n 1 358 LEU n 1 359 GLY n 1 360 SER n 1 361 VAL n 1 362 THR n 1 363 HIS n 1 364 GLU n 1 365 LEU n 1 366 ALA n 1 367 PRO n 1 368 GLY n 1 369 ILE n 1 370 ASP n 1 371 CYS n 1 372 PRO n 1 373 GLU n 1 374 THR n 1 375 ALA n 1 376 THR n 1 377 PHE n 1 378 LEU n 1 379 ASP n 1 380 THR n 1 381 PHE n 1 382 HIS n 1 383 TYR n 1 384 TYR n 1 385 ASP n 1 386 ALA n 1 387 ASP n 1 388 ASP n 1 389 PRO n 1 390 VAL n 1 391 HIS n 1 392 TYR n 1 393 PRO n 1 394 ARG n 1 395 ALA n 1 396 LEU n 1 397 CYS n 1 398 LEU n 1 399 PHE n 1 400 GLU n 1 401 MET n 1 402 PRO n 1 403 THR n 1 404 GLY n 1 405 VAL n 1 406 PRO n 1 407 LEU n 1 408 ARG n 1 409 ARG n 1 410 HIS n 1 411 PHE n 1 412 ASN n 1 413 SER n 1 414 ASN n 1 415 PHE n 1 416 LYS n 1 417 GLY n 1 418 GLY n 1 419 PHE n 1 420 ASN n 1 421 PHE n 1 422 TYR n 1 423 ALA n 1 424 GLY n 1 425 LEU n 1 426 LYS n 1 427 GLY n 1 428 GLN n 1 429 VAL n 1 430 LEU n 1 431 VAL n 1 432 LEU n 1 433 ARG n 1 434 THR n 1 435 THR n 1 436 SER n 1 437 THR n 1 438 VAL n 1 439 TYR n 1 440 ASN n 1 441 TPQ n 1 442 ASP n 1 443 TYR n 1 444 ILE n 1 445 TRP n 1 446 ASP n 1 447 PHE n 1 448 ILE n 1 449 PHE n 1 450 TYR n 1 451 PRO n 1 452 ASN n 1 453 GLY n 1 454 VAL n 1 455 MET n 1 456 GLU n 1 457 ALA n 1 458 LYS n 1 459 MET n 1 460 HIS n 1 461 ALA n 1 462 THR n 1 463 GLY n 1 464 TYR n 1 465 VAL n 1 466 HIS n 1 467 ALA n 1 468 THR n 1 469 PHE n 1 470 TYR n 1 471 THR n 1 472 PRO n 1 473 GLU n 1 474 GLY n 1 475 LEU n 1 476 ARG n 1 477 HIS n 1 478 GLY n 1 479 THR n 1 480 ARG n 1 481 LEU n 1 482 HIS n 1 483 THR n 1 484 HIS n 1 485 LEU n 1 486 ILE n 1 487 GLY n 1 488 ASN n 1 489 ILE n 1 490 HIS n 1 491 THR n 1 492 HIS n 1 493 LEU n 1 494 VAL n 1 495 HIS n 1 496 TYR n 1 497 ARG n 1 498 VAL n 1 499 ASP n 1 500 LEU n 1 501 ASP n 1 502 VAL n 1 503 ALA n 1 504 GLY n 1 505 THR n 1 506 LYS n 1 507 ASN n 1 508 SER n 1 509 PHE n 1 510 GLN n 1 511 THR n 1 512 LEU n 1 513 GLN n 1 514 MET n 1 515 LYS n 1 516 LEU n 1 517 GLU n 1 518 ASN n 1 519 ILE n 1 520 THR n 1 521 ASN n 1 522 PRO n 1 523 TRP n 1 524 SER n 1 525 PRO n 1 526 ARG n 1 527 HIS n 1 528 ARG n 1 529 VAL n 1 530 VAL n 1 531 GLN n 1 532 PRO n 1 533 THR n 1 534 LEU n 1 535 GLU n 1 536 GLN n 1 537 THR n 1 538 GLN n 1 539 TYR n 1 540 SER n 1 541 TRP n 1 542 GLU n 1 543 ARG n 1 544 GLN n 1 545 ALA n 1 546 ALA n 1 547 PHE n 1 548 ARG n 1 549 PHE n 1 550 LYS n 1 551 ARG n 1 552 LYS n 1 553 LEU n 1 554 PRO n 1 555 LYS n 1 556 TYR n 1 557 LEU n 1 558 LEU n 1 559 PHE n 1 560 THR n 1 561 SER n 1 562 PRO n 1 563 GLN n 1 564 GLU n 1 565 ASN n 1 566 PRO n 1 567 TRP n 1 568 GLY n 1 569 HIS n 1 570 LYS n 1 571 ARG n 1 572 SER n 1 573 TYR n 1 574 ARG n 1 575 LEU n 1 576 GLN n 1 577 ILE n 1 578 HIS n 1 579 SER n 1 580 MET n 1 581 ALA n 1 582 ASP n 1 583 GLN n 1 584 VAL n 1 585 LEU n 1 586 PRO n 1 587 PRO n 1 588 GLY n 1 589 TRP n 1 590 GLN n 1 591 GLU n 1 592 GLU n 1 593 GLN n 1 594 ALA n 1 595 ILE n 1 596 THR n 1 597 TRP n 1 598 ALA n 1 599 ARG n 1 600 TYR n 1 601 PRO n 1 602 LEU n 1 603 ALA n 1 604 VAL n 1 605 THR n 1 606 LYS n 1 607 TYR n 1 608 ARG n 1 609 GLU n 1 610 SER n 1 611 GLU n 1 612 LEU n 1 613 CYS n 1 614 SER n 1 615 SER n 1 616 SER n 1 617 ILE n 1 618 TYR n 1 619 HIS n 1 620 GLN n 1 621 ASN n 1 622 ASP n 1 623 PRO n 1 624 TRP n 1 625 ASP n 1 626 PRO n 1 627 PRO n 1 628 VAL n 1 629 VAL n 1 630 PHE n 1 631 GLU n 1 632 GLN n 1 633 PHE n 1 634 LEU n 1 635 HIS n 1 636 ASN n 1 637 ASN n 1 638 GLU n 1 639 ASN n 1 640 ILE n 1 641 GLU n 1 642 ASN n 1 643 GLU n 1 644 ASP n 1 645 LEU n 1 646 VAL n 1 647 ALA n 1 648 TRP n 1 649 VAL n 1 650 THR n 1 651 VAL n 1 652 GLY n 1 653 PHE n 1 654 LEU n 1 655 HIS n 1 656 ILE n 1 657 PRO n 1 658 HIS n 1 659 SER n 1 660 GLU n 1 661 ASP n 1 662 ILE n 1 663 PRO n 1 664 ASN n 1 665 THR n 1 666 ALA n 1 667 THR n 1 668 PRO n 1 669 GLY n 1 670 ASN n 1 671 SER n 1 672 VAL n 1 673 GLY n 1 674 PHE n 1 675 LEU n 1 676 LEU n 1 677 ARG n 1 678 PRO n 1 679 PHE n 1 680 ASN n 1 681 PHE n 1 682 PHE n 1 683 PRO n 1 684 GLU n 1 685 ASP n 1 686 PRO n 1 687 SER n 1 688 LEU n 1 689 ALA n 1 690 SER n 1 691 ARG n 1 692 ASP n 1 693 THR n 1 694 VAL n 1 695 ILE n 1 696 VAL n 1 697 TRP n 1 698 PRO n 1 699 ARG n 1 700 ASP n 1 701 ASN n 1 702 GLY n 1 703 PRO n 1 704 ASN n 1 705 TYR n 1 706 VAL n 1 707 GLN n 1 708 ARG n 1 709 TRP n 1 710 ILE n 1 711 PRO n 1 712 GLU n 1 713 ASP n 1 714 ARG n 1 715 ASP n 1 716 CYS n 1 717 SER n 1 718 MET n 1 719 PRO n 1 720 PRO n 1 721 PRO n 1 722 PHE n 1 723 SER n 1 724 TYR n 1 725 ASN n 1 726 GLY n 1 727 THR n 1 728 TYR n 1 729 ARG n 1 730 PRO n 1 731 VAL n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ABP1 _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line 'Schneider 2' _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ABP1_HUMAN _struct_ref.pdbx_db_accession P19801 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;PSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAV IFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDV VVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVH FGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTR LHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFT SPQENPWGHKRSYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWDPPVVFEQFLHNNENI ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPP PFSYNGTYRPV ; _struct_ref.pdbx_align_begin 21 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3HII A 1 ? 731 ? P19801 21 ? 751 ? 21 751 2 1 3HII B 1 ? 731 ? P19801 21 ? 751 ? 21 751 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3HII ARG A 1 ? UNP P19801 PRO 21 ENGINEERED 21 1 2 3HII ARG B 1 ? UNP P19801 PRO 21 ENGINEERED 21 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CU non-polymer . 'COPPER (II) ION' ? 'Cu 2' 63.546 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PNT non-polymer . '1,5-BIS(4-AMIDINOPHENOXY)PENTANE' ? 'C19 H24 N4 O2' 340.419 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TPQ 'L-peptide linking' n '5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE' '5-(2-CARBOXY-2-AMINOETHYL)-4-HYDROXY-1,2-BENZOQUINONE; 2,4,5-TRIHYDROXYPHENYLALANINE QUINONE; TOPA QUINONE' 'C9 H9 N O5' 211.171 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3HII _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.pdbx_mosaicity 0.431 _exptl_crystal.pdbx_mosaicity_esd ? _exptl_crystal.density_Matthews 2.58 _exptl_crystal.density_diffrn ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_percent_sol 52.24 _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 7.5 _exptl_crystal_grow.temp 298 _exptl_crystal_grow.pdbx_details '0.1M bis-tris propane, 20%(w/v) PEG 3350, 0.2M sodium sulfate, pH 7.5, vapor diffusion, hanging drop, temperature 298K' _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'MAR scanner 345 mm plate' _diffrn_detector.pdbx_collection_date 2008-11-05 _diffrn_detector.details 'OSMIC MIRRORS' # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator 'Ni FILTER' _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.5418 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'RIGAKU RU200' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.5418 _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? # _reflns.entry_id 3HII _reflns.d_resolution_high 2.149 _reflns.d_resolution_low 50.000 _reflns.number_obs 89751 _reflns.pdbx_Rmerge_I_obs 0.103 _reflns.pdbx_netI_over_sigmaI 9.903 _reflns.pdbx_chi_squared 1.067 _reflns.pdbx_redundancy 3.000 _reflns.percent_possible_obs 95.000 _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.number_all 89751 _reflns.pdbx_Rsym_value ? _reflns.B_iso_Wilson_estimate 29.96 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.149 _reflns_shell.d_res_low 2.23 _reflns_shell.number_measured_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_unique_obs ? _reflns_shell.Rmerge_I_obs 0.336 _reflns_shell.meanI_over_sigI_obs 2.7 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared 1.041 _reflns_shell.pdbx_redundancy 2.40 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 8090 _reflns_shell.percent_possible_all 87.10 _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3HII _refine.ls_d_res_high 2.149 _refine.ls_d_res_low 25.840 _refine.pdbx_ls_sigma_F 0.00 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 94.980 _refine.ls_number_reflns_obs 85093 _refine.ls_number_reflns_all 85093 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES: REFINED INDIVIDUALLY' _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.18359 _refine.ls_R_factor_R_work 0.18159 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free 0.22093 _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free 5.100 _refine.ls_number_reflns_R_free 4554 _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 21.017 _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.pdbx_isotropic_thermal_model ? _refine.aniso_B[1][1] 1.200 _refine.aniso_B[2][2] -0.940 _refine.aniso_B[3][3] -0.270 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc 0.948 _refine.correlation_coeff_Fo_to_Fc_free 0.926 _refine.overall_SU_R_Cruickshank_DPI 0.245 _refine.overall_SU_R_free 0.190 _refine.pdbx_overall_ESU_R 0.245 _refine.pdbx_overall_ESU_R_Free 0.190 _refine.overall_SU_ML 0.118 _refine.overall_SU_B 4.494 _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.200 _refine.pdbx_solvent_ion_probe_radii 0.800 _refine.pdbx_solvent_shrinkage_radii 0.800 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model 'PDB ENTRY 3HI7' _refine.pdbx_method_to_determine_struct 'BY REFINEMENT' _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set 0.866 _refine.B_iso_max 62.23 _refine.B_iso_min 11.86 _refine.occupancy_max 1.00 _refine.occupancy_min 0.30 _refine.pdbx_ls_sigma_I ? _refine.ls_redundancy_reflns_obs ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.overall_FOM_free_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_phase_error ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 11354 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 241 _refine_hist.number_atoms_solvent 916 _refine_hist.number_atoms_total 12511 _refine_hist.d_res_high 2.149 _refine_hist.d_res_low 25.840 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.008 0.021 ? 12215 'X-RAY DIFFRACTION' ? r_bond_other_d 0.001 0.020 ? 8166 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.199 1.957 ? 16761 'X-RAY DIFFRACTION' ? r_angle_other_deg 0.784 3.000 ? 19717 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.521 5.000 ? 1482 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 30.900 22.920 ? 572 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 11.793 15.000 ? 1721 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 13.985 15.000 ? 76 'X-RAY DIFFRACTION' ? r_chiral_restr 0.070 0.200 ? 1780 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.005 0.021 ? 13734 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.001 0.020 ? 2697 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.431 1.500 ? 7254 'X-RAY DIFFRACTION' ? r_mcbond_other 0.081 1.500 ? 2876 'X-RAY DIFFRACTION' ? r_mcangle_it 0.808 2.000 ? 11775 'X-RAY DIFFRACTION' ? r_scbond_it 1.191 3.000 ? 4961 'X-RAY DIFFRACTION' ? r_scangle_it 1.932 4.500 ? 4963 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 2.149 _refine_ls_shell.d_res_low 2.204 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 84.910 _refine_ls_shell.number_reflns_R_work 5522 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.232 _refine_ls_shell.R_factor_R_free 0.301 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 290 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.number_reflns_all 5812 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3HII _struct.title 'Crystal structure of human diamine oxidase in complex with the inhibitor pentamidine' _struct.pdbx_descriptor 'Amiloride-sensitive amine oxidase (E.C.1.4.3.22)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3HII _struct_keywords.text ;oxidoreductase, copper amine oxidase, topaquinone, TPQ, diamine oxidase, DAO, human, pentamidine, Glycoprotein, Heparin-binding, Metal-binding, Secreted ; _struct_keywords.pdbx_keywords OXIDOREDUCTASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 4 ? G N N 5 ? H N N 6 ? I N N 6 ? J N N 7 ? K N N 6 ? L N N 6 ? M N N 6 ? N N N 6 ? O N N 2 ? P N N 3 ? Q N N 3 ? R N N 5 ? S N N 6 ? T N N 6 ? U N N 6 ? V N N 6 ? W N N 6 ? X N N 6 ? Y N N 8 ? Z N N 8 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ARG A 8 ? SER A 14 ? ARG A 28 SER A 34 5 ? 7 HELX_P HELX_P2 2 SER A 17 ? LYS A 31 ? SER A 37 LYS A 51 1 ? 15 HELX_P HELX_P3 3 LYS A 32 ? ARG A 35 ? LYS A 52 ARG A 55 5 ? 4 HELX_P HELX_P4 4 LYS A 58 ? GLY A 69 ? LYS A 78 GLY A 89 1 ? 12 HELX_P HELX_P5 5 SER A 116 ? ARG A 121 ? SER A 136 ARG A 141 1 ? 6 HELX_P HELX_P6 6 SER A 124 ? THR A 139 ? SER A 144 THR A 159 1 ? 16 HELX_P HELX_P7 7 LEU A 142 ? GLY A 151 ? LEU A 162 GLY A 171 1 ? 10 HELX_P HELX_P8 8 GLY A 189 ? LEU A 192 ? GLY A 209 LEU A 212 5 ? 4 HELX_P HELX_P9 9 ASP A 207 ? TRP A 211 ? ASP A 227 TRP A 231 5 ? 5 HELX_P HELX_P10 10 SER A 225 ? ASP A 235 ? SER A 245 ASP A 255 1 ? 11 HELX_P HELX_P11 11 THR A 343 ? THR A 349 ? THR A 363 THR A 369 1 ? 7 HELX_P HELX_P12 12 VAL A 354 ? VAL A 361 ? VAL A 374 VAL A 381 5 ? 8 HELX_P HELX_P13 13 THR A 471 ? ARG A 476 ? THR A 491 ARG A 496 5 ? 6 HELX_P HELX_P14 14 TRP A 541 ? ALA A 546 ? TRP A 561 ALA A 566 5 ? 6 HELX_P HELX_P15 15 TRP A 589 ? TYR A 600 ? TRP A 609 TYR A 620 5 ? 12 HELX_P HELX_P16 16 ARG A 608 ? LEU A 612 ? ARG A 628 LEU A 632 5 ? 5 HELX_P HELX_P17 17 GLU A 631 ? ASN A 636 ? GLU A 651 ASN A 656 1 ? 6 HELX_P HELX_P18 18 HIS A 658 ? ILE A 662 ? HIS A 678 ILE A 682 5 ? 5 HELX_P HELX_P19 19 ASP A 685 ? SER A 690 ? ASP A 705 SER A 710 5 ? 6 HELX_P HELX_P20 20 ARG B 8 ? SER B 14 ? ARG B 28 SER B 34 5 ? 7 HELX_P HELX_P21 21 SER B 17 ? SER B 30 ? SER B 37 SER B 50 1 ? 14 HELX_P HELX_P22 22 LYS B 31 ? ARG B 35 ? LYS B 51 ARG B 55 5 ? 5 HELX_P HELX_P23 23 LYS B 58 ? LYS B 68 ? LYS B 78 LYS B 88 1 ? 11 HELX_P HELX_P24 24 SER B 116 ? ARG B 121 ? SER B 136 ARG B 141 1 ? 6 HELX_P HELX_P25 25 SER B 124 ? THR B 139 ? SER B 144 THR B 159 1 ? 16 HELX_P HELX_P26 26 LEU B 142 ? GLY B 151 ? LEU B 162 GLY B 171 1 ? 10 HELX_P HELX_P27 27 GLY B 189 ? LEU B 192 ? GLY B 209 LEU B 212 5 ? 4 HELX_P HELX_P28 28 ASP B 207 ? TRP B 211 ? ASP B 227 TRP B 231 5 ? 5 HELX_P HELX_P29 29 SER B 225 ? ASP B 235 ? SER B 245 ASP B 255 1 ? 11 HELX_P HELX_P30 30 THR B 343 ? THR B 349 ? THR B 363 THR B 369 1 ? 7 HELX_P HELX_P31 31 VAL B 354 ? VAL B 361 ? VAL B 374 VAL B 381 5 ? 8 HELX_P HELX_P32 32 THR B 471 ? ARG B 476 ? THR B 491 ARG B 496 5 ? 6 HELX_P HELX_P33 33 TRP B 541 ? ALA B 546 ? TRP B 561 ALA B 566 5 ? 6 HELX_P HELX_P34 34 TRP B 589 ? TYR B 600 ? TRP B 609 TYR B 620 5 ? 12 HELX_P HELX_P35 35 ARG B 608 ? LEU B 612 ? ARG B 628 LEU B 632 5 ? 5 HELX_P HELX_P36 36 VAL B 629 ? HIS B 635 ? VAL B 649 HIS B 655 5 ? 7 HELX_P HELX_P37 37 HIS B 658 ? ILE B 662 ? HIS B 678 ILE B 682 5 ? 5 HELX_P HELX_P38 38 ASP B 685 ? SER B 690 ? ASP B 705 SER B 710 5 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 157 SG ? ? ? 1_555 A CYS 161 SG ? ? A CYS 177 A CYS 181 1_555 ? ? ? ? ? ? ? 2.066 ? disulf2 disulf ? ? A CYS 371 SG ? ? ? 1_555 A CYS 397 SG ? ? A CYS 391 A CYS 417 1_555 ? ? ? ? ? ? ? 2.045 ? disulf3 disulf ? ? A CYS 716 SG ? ? ? 1_555 B CYS 716 SG ? ? A CYS 736 B CYS 736 1_555 ? ? ? ? ? ? ? 2.049 ? disulf4 disulf ? ? B CYS 157 SG ? ? ? 1_555 B CYS 161 SG ? ? B CYS 177 B CYS 181 1_555 ? ? ? ? ? ? ? 2.046 ? disulf5 disulf ? ? B CYS 371 SG ? ? ? 1_555 B CYS 397 SG ? ? B CYS 391 B CYS 417 1_555 ? ? ? ? ? ? ? 2.066 ? covale1 covale ? ? A ASN 440 C ? ? ? 1_555 A TPQ 441 N ? ? A ASN 460 A TPQ 461 1_555 ? ? ? ? ? ? ? 1.334 ? covale2 covale ? ? A TPQ 441 C ? ? ? 1_555 A ASP 442 N ? ? A TPQ 461 A ASP 462 1_555 ? ? ? ? ? ? ? 1.330 ? covale3 covale ? ? B ASN 440 C ? ? ? 1_555 B TPQ 441 N ? ? B ASN 460 B TPQ 461 1_555 ? ? ? ? ? ? ? 1.332 ? covale4 covale ? ? B TPQ 441 C ? ? ? 1_555 B ASP 442 N ? ? B TPQ 461 B ASP 462 1_555 ? ? ? ? ? ? ? 1.332 ? covale5 covale ? ? A ASN 90 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 110 A NAG 1101 1_555 ? ? ? ? ? ? ? 1.443 ? metalc1 metalc ? ? A TPQ 441 O4 ? ? ? 1_555 C CU . CU ? ? A TPQ 461 A CU 801 1_555 ? ? ? ? ? ? ? 2.233 ? metalc2 metalc ? ? A HIS 490 NE2 ? ? ? 1_555 C CU . CU ? ? A HIS 510 A CU 801 1_555 ? ? ? ? ? ? ? 2.085 ? metalc3 metalc ? ? A HIS 492 NE2 ? ? ? 1_555 C CU . CU ? ? A HIS 512 A CU 801 1_555 ? ? ? ? ? ? ? 2.034 ? metalc4 metalc ? ? A ASP 499 OD1 ? ? ? 1_555 D CA . CA ? ? A ASP 519 A CA 802 1_555 ? ? ? ? ? ? ? 2.313 ? metalc5 metalc ? ? A LEU 500 O ? ? ? 1_555 D CA . CA ? ? A LEU 520 A CA 802 1_555 ? ? ? ? ? ? ? 2.322 ? metalc6 metalc ? ? A ASP 501 OD1 ? ? ? 1_555 D CA . CA ? ? A ASP 521 A CA 802 1_555 ? ? ? ? ? ? ? 2.382 ? covale6 covale ? ? A ASN 518 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 538 A NAG 5381 1_555 ? ? ? ? ? ? ? 1.440 ? metalc7 metalc ? ? A GLU 542 OE1 ? ? ? 1_555 E CA . CA ? ? A GLU 562 A CA 803 1_555 ? ? ? ? ? ? ? 2.504 ? metalc8 metalc ? ? A GLU 542 OE2 ? ? ? 1_555 E CA . CA ? ? A GLU 562 A CA 803 1_555 ? ? ? ? ? ? ? 2.610 ? metalc9 metalc ? ? A PHE 633 O ? ? ? 1_555 E CA . CA ? ? A PHE 653 A CA 803 1_555 ? ? ? ? ? ? ? 2.326 ? metalc10 metalc ? ? A ASN 636 OD1 ? ? ? 1_555 E CA . CA ? ? A ASN 656 A CA 803 1_555 ? ? ? ? ? ? ? 2.450 ? metalc11 metalc ? ? A GLU 638 OE1 ? ? ? 1_555 E CA . CA ? ? A GLU 658 A CA 803 1_555 ? ? ? ? ? ? ? 2.449 ? metalc12 metalc ? ? A ASP 644 OD1 ? ? ? 1_555 D CA . CA ? ? A ASP 664 A CA 802 1_555 ? ? ? ? ? ? ? 2.337 ? metalc13 metalc ? ? A LEU 645 O ? ? ? 1_555 D CA . CA ? ? A LEU 665 A CA 802 1_555 ? ? ? ? ? ? ? 2.361 ? metalc14 metalc ? ? A HIS 655 ND1 ? ? ? 1_555 C CU . CU ? ? A HIS 675 A CU 801 1_555 ? ? ? ? ? ? ? 2.020 ? covale7 covale ? ? A ASN 725 ND2 ? ? ? 1_555 M NAG . C1 ? ? A ASN 745 A NAG 7451 1_555 ? ? ? ? ? ? ? 1.428 ? covale8 covale ? ? B ASN 90 ND2 ? ? ? 1_555 S NAG . C1 ? ? B ASN 110 B NAG 1101 1_555 ? ? ? ? ? ? ? 1.444 ? metalc15 metalc ? ? B TPQ 441 O4 ? ? ? 1_555 O CU . CU ? ? B TPQ 461 B CU 801 1_555 ? ? ? ? ? ? ? 2.159 ? metalc16 metalc ? ? B HIS 490 NE2 ? ? ? 1_555 O CU . CU ? ? B HIS 510 B CU 801 1_555 ? ? ? ? ? ? ? 2.114 ? metalc17 metalc ? ? B HIS 492 NE2 ? ? ? 1_555 O CU . CU ? ? B HIS 512 B CU 801 1_555 ? ? ? ? ? ? ? 2.000 ? metalc18 metalc ? ? B ASP 499 OD1 ? ? ? 1_555 P CA . CA ? ? B ASP 519 B CA 802 1_555 ? ? ? ? ? ? ? 2.266 ? metalc19 metalc ? ? B LEU 500 O ? ? ? 1_555 P CA . CA ? ? B LEU 520 B CA 802 1_555 ? ? ? ? ? ? ? 2.341 ? metalc20 metalc ? ? B ASP 501 OD1 ? ? ? 1_555 P CA . CA ? ? B ASP 521 B CA 802 1_555 ? ? ? ? ? ? ? 2.220 ? covale9 covale ? ? B ASN 518 ND2 ? ? ? 1_555 U NAG . C1 ? ? B ASN 538 B NAG 5381 1_555 ? ? ? ? ? ? ? 1.431 ? metalc21 metalc ? ? B GLU 542 OE1 ? ? ? 1_555 Q CA . CA ? ? B GLU 562 B CA 803 1_555 ? ? ? ? ? ? ? 2.597 ? metalc22 metalc ? ? B GLU 542 OE2 ? ? ? 1_555 Q CA . CA ? ? B GLU 562 B CA 803 1_555 ? ? ? ? ? ? ? 2.700 ? metalc23 metalc ? ? B PHE 633 O ? ? ? 1_555 Q CA . CA ? ? B PHE 653 B CA 803 1_555 ? ? ? ? ? ? ? 2.406 ? metalc24 metalc ? ? B ASN 636 OD1 ? ? ? 1_555 Q CA . CA ? ? B ASN 656 B CA 803 1_555 ? ? ? ? ? ? ? 2.347 ? metalc25 metalc ? ? B GLU 638 OE1 ? ? ? 1_555 Q CA . CA ? ? B GLU 658 B CA 803 1_555 ? ? ? ? ? ? ? 2.475 ? metalc26 metalc ? ? B ASP 644 OD1 ? ? ? 1_555 P CA . CA ? ? B ASP 664 B CA 802 1_555 ? ? ? ? ? ? ? 2.259 ? metalc27 metalc ? ? B LEU 645 O ? ? ? 1_555 P CA . CA ? ? B LEU 665 B CA 802 1_555 ? ? ? ? ? ? ? 2.316 ? metalc28 metalc ? ? B HIS 655 ND1 ? ? ? 1_555 O CU . CU ? ? B HIS 675 B CU 801 1_555 ? ? ? ? ? ? ? 2.020 ? covale10 covale ? ? B ASN 725 ND2 ? ? ? 1_555 W NAG . C1 ? ? B ASN 745 B NAG 7451 1_555 ? ? ? ? ? ? ? 1.436 ? covale11 covale ? ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 1101 A NAG 1102 1_555 ? ? ? ? ? ? ? 1.438 ? covale12 covale ? ? I NAG . O4 ? ? ? 1_555 J BMA . C1 ? ? A NAG 1102 A BMA 1103 1_555 ? ? ? ? ? ? ? 1.456 ? covale13 covale ? ? K NAG . O4 ? ? ? 1_555 L NAG . C1 ? ? A NAG 5381 A NAG 5382 1_555 ? ? ? ? ? ? ? 1.438 ? covale14 covale ? ? M NAG . O4 ? ? ? 1_555 N NAG . C1 ? ? A NAG 7451 A NAG 7452 1_555 ? ? ? ? ? ? ? 1.438 ? covale15 covale ? ? S NAG . O4 ? ? ? 1_555 T NAG . C1 ? ? B NAG 1101 B NAG 1102 1_555 ? ? ? ? ? ? ? 1.435 ? covale16 covale ? ? U NAG . O4 ? ? ? 1_555 V NAG . C1 ? ? B NAG 5381 B NAG 5382 1_555 ? ? ? ? ? ? ? 1.436 ? covale17 covale ? ? W NAG . O4 ? ? ? 1_555 X NAG . C1 ? ? B NAG 7451 B NAG 7452 1_555 ? ? ? ? ? ? ? 1.443 ? metalc29 metalc ? ? D CA . CA ? ? ? 1_555 Y HOH . O ? ? A CA 802 A HOH 20 1_555 ? ? ? ? ? ? ? 2.507 ? metalc30 metalc ? ? E CA . CA ? ? ? 1_555 Y HOH . O ? ? A CA 803 A HOH 758 1_555 ? ? ? ? ? ? ? 2.381 ? metalc31 metalc ? ? E CA . CA ? ? ? 1_555 Y HOH . O ? ? A CA 803 A HOH 817 1_555 ? ? ? ? ? ? ? 2.324 ? metalc32 metalc ? ? P CA . CA ? ? ? 1_555 Z HOH . O ? ? B CA 802 B HOH 876 1_555 ? ? ? ? ? ? ? 2.440 ? metalc33 metalc ? ? Q CA . CA ? ? ? 1_555 Z HOH . O ? ? B CA 803 B HOH 5 1_555 ? ? ? ? ? ? ? 2.384 ? metalc34 metalc ? ? Q CA . CA ? ? ? 1_555 Z HOH . O ? ? B CA 803 B HOH 834 1_555 ? ? ? ? ? ? ? 2.326 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 97 A . ? GLY 117 A PRO 98 A ? PRO 118 A 1 -6.45 2 LEU 99 A . ? LEU 119 A PRO 100 A ? PRO 120 A 1 0.91 3 ALA 168 A . ? ALA 188 A PRO 169 A ? PRO 189 A 1 0.23 4 ILE 662 A . ? ILE 682 A PRO 663 A ? PRO 683 A 1 3.46 5 GLY 97 B . ? GLY 117 B PRO 98 B ? PRO 118 B 1 -4.65 6 LEU 99 B . ? LEU 119 B PRO 100 B ? PRO 120 B 1 -4.42 7 ALA 168 B . ? ALA 188 B PRO 169 B ? PRO 189 B 1 2.85 8 ILE 662 B . ? ILE 682 B PRO 663 B ? PRO 683 B 1 0.73 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 20 ? B ? 9 ? C ? 5 ? D ? 5 ? E ? 2 ? F ? 4 ? G ? 3 ? H ? 20 ? I ? 9 ? J ? 5 ? K ? 5 ? L ? 4 ? M ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel A 5 6 ? anti-parallel A 6 7 ? anti-parallel A 7 8 ? anti-parallel A 8 9 ? anti-parallel A 9 10 ? anti-parallel A 10 11 ? anti-parallel A 11 12 ? anti-parallel A 12 13 ? anti-parallel A 13 14 ? anti-parallel A 14 15 ? anti-parallel A 15 16 ? anti-parallel A 16 17 ? anti-parallel A 17 18 ? anti-parallel A 18 19 ? anti-parallel A 19 20 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel B 8 9 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel C 4 5 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel H 12 13 ? anti-parallel H 13 14 ? anti-parallel H 14 15 ? anti-parallel H 15 16 ? anti-parallel H 16 17 ? anti-parallel H 17 18 ? anti-parallel H 18 19 ? anti-parallel H 19 20 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel I 5 6 ? anti-parallel I 6 7 ? anti-parallel I 7 8 ? anti-parallel I 8 9 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 TYR A 104 ? LEU A 108 ? TYR A 124 LEU A 128 A 2 ASN A 90 ? GLY A 97 ? ASN A 110 GLY A 117 A 3 GLU A 76 ? PHE A 83 ? GLU A 96 PHE A 103 A 4 ASN A 47 ? LEU A 55 ? ASN A 67 LEU A 75 A 5 THR A 376 ? TYR A 384 ? THR A 396 TYR A 404 A 6 VAL A 390 ? PRO A 402 ? VAL A 410 PRO A 422 A 7 GLN A 428 ? SER A 436 ? GLN A 448 SER A 456 A 8 TPQ A 441 ? PHE A 449 ? TPQ A 461 PHE A 469 A 9 MET A 455 ? GLY A 463 ? MET A 475 GLY A 483 A 10 SER A 671 ? PHE A 679 ? SER A 691 PHE A 699 A 11 LYS A 570 ? HIS A 578 ? LYS A 590 HIS A 598 A 12 TYR A 556 ? GLU A 564 ? TYR A 576 GLU A 584 A 13 LYS A 506 ? THR A 520 ? LYS A 526 THR A 540 A 14 GLU A 643 ? HIS A 655 ? GLU A 663 HIS A 675 A 15 HIS A 490 ? LEU A 500 ? HIS A 510 LEU A 520 A 16 GLU A 324 ? TYR A 339 ? GLU A 344 TYR A 359 A 17 GLY A 313 ? PHE A 321 ? GLY A 333 PHE A 341 A 18 TRP A 302 ? ARG A 309 ? TRP A 322 ARG A 329 A 19 ALA A 296 ? TYR A 299 ? ALA A 316 TYR A 319 A 20 ARG A 291 ? GLU A 293 ? ARG A 311 GLU A 313 B 1 ARG A 291 ? GLU A 293 ? ARG A 311 GLU A 313 B 2 ALA A 296 ? TYR A 299 ? ALA A 316 TYR A 319 B 3 TRP A 302 ? ARG A 309 ? TRP A 322 ARG A 329 B 4 GLY A 313 ? PHE A 321 ? GLY A 333 PHE A 341 B 5 GLU A 324 ? TYR A 339 ? GLU A 344 TYR A 359 B 6 HIS A 490 ? LEU A 500 ? HIS A 510 LEU A 520 B 7 GLU A 643 ? HIS A 655 ? GLU A 663 HIS A 675 B 8 LYS A 506 ? THR A 520 ? LYS A 526 THR A 540 B 9 ARG A 528 ? TYR A 539 ? ARG A 548 TYR A 559 C 1 LEU A 602 ? LYS A 606 ? LEU A 622 LYS A 626 C 2 GLU A 643 ? HIS A 655 ? GLU A 663 HIS A 675 C 3 HIS A 490 ? LEU A 500 ? HIS A 510 LEU A 520 C 4 GLU A 324 ? TYR A 339 ? GLU A 344 TYR A 359 C 5 LYS A 350 ? LEU A 352 ? LYS A 370 LEU A 372 D 1 LEU A 162 ? ASP A 166 ? LEU A 182 ASP A 186 D 2 ARG A 178 ? ARG A 185 ? ARG A 198 ARG A 205 D 3 PRO A 194 ? ASP A 202 ? PRO A 214 ASP A 222 D 4 ALA A 212 ? TYR A 218 ? ALA A 232 TYR A 238 D 5 LYS A 221 ? PHE A 222 ? LYS A 241 PHE A 242 E 1 ARG A 281 ? VAL A 283 ? ARG A 301 VAL A 303 E 2 ARG B 281 ? VAL B 283 ? ARG B 301 VAL B 303 F 1 ARG A 408 ? SER A 413 ? ARG A 428 SER A 433 F 2 PHE A 419 ? LEU A 425 ? PHE A 439 LEU A 445 F 3 VAL A 694 ? TRP A 697 ? VAL A 714 TRP A 717 F 4 TYR A 705 ? GLN A 707 ? TYR A 725 GLN A 727 G 1 ALA A 467 ? PHE A 469 ? ALA A 487 PHE A 489 G 2 LEU A 485 ? ASN A 488 ? LEU A 505 ASN A 508 G 3 GLY A 478 ? HIS A 482 ? GLY A 498 HIS A 502 H 1 TYR B 104 ? ALA B 107 ? TYR B 124 ALA B 127 H 2 ASN B 90 ? GLY B 97 ? ASN B 110 GLY B 117 H 3 GLU B 76 ? PHE B 83 ? GLU B 96 PHE B 103 H 4 ASN B 47 ? LEU B 55 ? ASN B 67 LEU B 75 H 5 THR B 376 ? TYR B 384 ? THR B 396 TYR B 404 H 6 VAL B 390 ? PRO B 402 ? VAL B 410 PRO B 422 H 7 GLN B 428 ? THR B 437 ? GLN B 448 THR B 457 H 8 TPQ B 441 ? PHE B 449 ? TPQ B 461 PHE B 469 H 9 MET B 455 ? GLY B 463 ? MET B 475 GLY B 483 H 10 SER B 671 ? PHE B 679 ? SER B 691 PHE B 699 H 11 LYS B 570 ? HIS B 578 ? LYS B 590 HIS B 598 H 12 TYR B 556 ? GLU B 564 ? TYR B 576 GLU B 584 H 13 LYS B 506 ? THR B 520 ? LYS B 526 THR B 540 H 14 GLU B 643 ? HIS B 655 ? GLU B 663 HIS B 675 H 15 HIS B 490 ? LEU B 500 ? HIS B 510 LEU B 520 H 16 GLU B 324 ? TYR B 339 ? GLU B 344 TYR B 359 H 17 GLY B 313 ? PHE B 321 ? GLY B 333 PHE B 341 H 18 TRP B 302 ? ARG B 309 ? TRP B 322 ARG B 329 H 19 ALA B 296 ? TYR B 299 ? ALA B 316 TYR B 319 H 20 ARG B 291 ? GLU B 293 ? ARG B 311 GLU B 313 I 1 ARG B 291 ? GLU B 293 ? ARG B 311 GLU B 313 I 2 ALA B 296 ? TYR B 299 ? ALA B 316 TYR B 319 I 3 TRP B 302 ? ARG B 309 ? TRP B 322 ARG B 329 I 4 GLY B 313 ? PHE B 321 ? GLY B 333 PHE B 341 I 5 GLU B 324 ? TYR B 339 ? GLU B 344 TYR B 359 I 6 HIS B 490 ? LEU B 500 ? HIS B 510 LEU B 520 I 7 GLU B 643 ? HIS B 655 ? GLU B 663 HIS B 675 I 8 LYS B 506 ? THR B 520 ? LYS B 526 THR B 540 I 9 ARG B 528 ? GLN B 538 ? ARG B 548 GLN B 558 J 1 LEU B 602 ? LYS B 606 ? LEU B 622 LYS B 626 J 2 GLU B 643 ? HIS B 655 ? GLU B 663 HIS B 675 J 3 HIS B 490 ? LEU B 500 ? HIS B 510 LEU B 520 J 4 GLU B 324 ? TYR B 339 ? GLU B 344 TYR B 359 J 5 LYS B 350 ? LEU B 352 ? LYS B 370 LEU B 372 K 1 LEU B 162 ? ASP B 166 ? LEU B 182 ASP B 186 K 2 ARG B 178 ? ARG B 185 ? ARG B 198 ARG B 205 K 3 PRO B 194 ? ASP B 202 ? PRO B 214 ASP B 222 K 4 ALA B 212 ? TYR B 218 ? ALA B 232 TYR B 238 K 5 LYS B 221 ? PHE B 222 ? LYS B 241 PHE B 242 L 1 ARG B 408 ? SER B 413 ? ARG B 428 SER B 433 L 2 PHE B 419 ? LEU B 425 ? PHE B 439 LEU B 445 L 3 VAL B 694 ? TRP B 697 ? VAL B 714 TRP B 717 L 4 TYR B 705 ? GLN B 707 ? TYR B 725 GLN B 727 M 1 ALA B 467 ? PHE B 469 ? ALA B 487 PHE B 489 M 2 LEU B 485 ? ASN B 488 ? LEU B 505 ASN B 508 M 3 GLY B 478 ? HIS B 482 ? GLY B 498 HIS B 502 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O ARG A 106 ? O ARG A 126 N ALA A 95 ? N ALA A 115 A 2 3 O VAL A 96 ? O VAL A 116 N ALA A 77 ? N ALA A 97 A 3 4 O ARG A 78 ? O ARG A 98 N GLU A 53 ? N GLU A 73 A 4 5 N ILE A 52 ? N ILE A 72 O TYR A 383 ? O TYR A 403 A 5 6 N THR A 380 ? N THR A 400 O TYR A 392 ? O TYR A 412 A 6 7 N PHE A 399 ? N PHE A 419 O VAL A 431 ? O VAL A 451 A 7 8 N LEU A 432 ? N LEU A 452 O PHE A 447 ? O PHE A 467 A 8 9 N ILE A 448 ? N ILE A 468 O GLU A 456 ? O GLU A 476 A 9 10 N MET A 455 ? N MET A 475 O LEU A 676 ? O LEU A 696 A 10 11 O ARG A 677 ? O ARG A 697 N ARG A 574 ? N ARG A 594 A 11 12 O ARG A 571 ? O ARG A 591 N GLN A 563 ? N GLN A 583 A 12 13 O LEU A 558 ? O LEU A 578 N GLN A 510 ? N GLN A 530 A 13 14 N ASN A 507 ? N ASN A 527 O GLU A 643 ? O GLU A 663 A 14 15 O VAL A 651 ? O VAL A 671 N VAL A 494 ? N VAL A 514 A 15 16 O LEU A 493 ? O LEU A 513 N VAL A 336 ? N VAL A 356 A 16 17 O ILE A 326 ? O ILE A 346 N VAL A 319 ? N VAL A 339 A 17 18 O HIS A 320 ? O HIS A 340 N SER A 303 ? N SER A 323 A 18 19 O PHE A 304 ? O PHE A 324 N VAL A 297 ? N VAL A 317 A 19 20 O LEU A 298 ? O LEU A 318 N ARG A 291 ? N ARG A 311 B 1 2 N ARG A 291 ? N ARG A 311 O LEU A 298 ? O LEU A 318 B 2 3 N VAL A 297 ? N VAL A 317 O PHE A 304 ? O PHE A 324 B 3 4 N SER A 303 ? N SER A 323 O HIS A 320 ? O HIS A 340 B 4 5 N VAL A 319 ? N VAL A 339 O ILE A 326 ? O ILE A 346 B 5 6 N VAL A 336 ? N VAL A 356 O LEU A 493 ? O LEU A 513 B 6 7 N VAL A 494 ? N VAL A 514 O VAL A 651 ? O VAL A 671 B 7 8 O GLU A 643 ? O GLU A 663 N ASN A 507 ? N ASN A 527 B 8 9 N ILE A 519 ? N ILE A 539 O VAL A 529 ? O VAL A 549 C 1 2 N THR A 605 ? N THR A 625 O VAL A 646 ? O VAL A 666 C 2 3 O VAL A 651 ? O VAL A 671 N VAL A 494 ? N VAL A 514 C 3 4 O LEU A 493 ? O LEU A 513 N VAL A 336 ? N VAL A 356 C 4 5 N ALA A 337 ? N ALA A 357 O TYR A 351 ? O TYR A 371 D 1 2 N ALA A 163 ? N ALA A 183 O GLN A 184 ? O GLN A 204 D 2 3 N SER A 179 ? N SER A 199 O VAL A 201 ? O VAL A 221 D 3 4 N GLU A 198 ? N GLU A 218 O TRP A 217 ? O TRP A 237 D 4 5 N TYR A 218 ? N TYR A 238 O LYS A 221 ? O LYS A 241 E 1 2 N VAL A 283 ? N VAL A 303 O ARG B 281 ? O ARG B 301 F 1 2 N ASN A 412 ? N ASN A 432 O ASN A 420 ? O ASN A 440 F 2 3 N TYR A 422 ? N TYR A 442 O VAL A 696 ? O VAL A 716 F 3 4 N ILE A 695 ? N ILE A 715 O GLN A 707 ? O GLN A 727 G 1 2 N THR A 468 ? N THR A 488 O ILE A 486 ? O ILE A 506 G 2 3 O GLY A 487 ? O GLY A 507 N THR A 479 ? N THR A 499 H 1 2 O ARG B 106 ? O ARG B 126 N ALA B 95 ? N ALA B 115 H 2 3 O ASN B 90 ? O ASN B 110 N PHE B 83 ? N PHE B 103 H 3 4 O ARG B 78 ? O ARG B 98 N GLU B 53 ? N GLU B 73 H 4 5 N ILE B 52 ? N ILE B 72 O TYR B 383 ? O TYR B 403 H 5 6 N THR B 380 ? N THR B 400 O TYR B 392 ? O TYR B 412 H 6 7 N PHE B 399 ? N PHE B 419 O VAL B 431 ? O VAL B 451 H 7 8 N SER B 436 ? N SER B 456 O TYR B 443 ? O TYR B 463 H 8 9 N ASP B 446 ? N ASP B 466 O LYS B 458 ? O LYS B 478 H 9 10 N MET B 455 ? N MET B 475 O LEU B 676 ? O LEU B 696 H 10 11 O ARG B 677 ? O ARG B 697 N ARG B 574 ? N ARG B 594 H 11 12 O ARG B 571 ? O ARG B 591 N SER B 561 ? N SER B 581 H 12 13 O LEU B 558 ? O LEU B 578 N GLN B 510 ? N GLN B 530 H 13 14 N ASN B 507 ? N ASN B 527 O GLU B 643 ? O GLU B 663 H 14 15 O ALA B 647 ? O ALA B 667 N VAL B 498 ? N VAL B 518 H 15 16 O HIS B 495 ? O HIS B 515 N GLN B 333 ? N GLN B 353 H 16 17 O ILE B 326 ? O ILE B 346 N VAL B 319 ? N VAL B 339 H 17 18 O HIS B 320 ? O HIS B 340 N SER B 303 ? N SER B 323 H 18 19 O PHE B 304 ? O PHE B 324 N VAL B 297 ? N VAL B 317 H 19 20 O LEU B 298 ? O LEU B 318 N ARG B 291 ? N ARG B 311 I 1 2 N ARG B 291 ? N ARG B 311 O LEU B 298 ? O LEU B 318 I 2 3 N VAL B 297 ? N VAL B 317 O PHE B 304 ? O PHE B 324 I 3 4 N SER B 303 ? N SER B 323 O HIS B 320 ? O HIS B 340 I 4 5 N VAL B 319 ? N VAL B 339 O ILE B 326 ? O ILE B 346 I 5 6 N GLN B 333 ? N GLN B 353 O HIS B 495 ? O HIS B 515 I 6 7 N VAL B 498 ? N VAL B 518 O ALA B 647 ? O ALA B 667 I 7 8 O GLU B 643 ? O GLU B 663 N ASN B 507 ? N ASN B 527 I 8 9 N THR B 511 ? N THR B 531 O THR B 537 ? O THR B 557 J 1 2 N THR B 605 ? N THR B 625 O VAL B 646 ? O VAL B 666 J 2 3 O ALA B 647 ? O ALA B 667 N VAL B 498 ? N VAL B 518 J 3 4 O HIS B 495 ? O HIS B 515 N GLN B 333 ? N GLN B 353 J 4 5 N ALA B 337 ? N ALA B 357 O TYR B 351 ? O TYR B 371 K 1 2 N ALA B 163 ? N ALA B 183 O GLN B 184 ? O GLN B 204 K 2 3 N ILE B 183 ? N ILE B 203 O THR B 195 ? O THR B 215 K 3 4 N GLU B 198 ? N GLU B 218 O TRP B 217 ? O TRP B 237 K 4 5 N TYR B 218 ? N TYR B 238 O LYS B 221 ? O LYS B 241 L 1 2 N ASN B 412 ? N ASN B 432 O ASN B 420 ? O ASN B 440 L 2 3 N TYR B 422 ? N TYR B 442 O VAL B 696 ? O VAL B 716 L 3 4 N ILE B 695 ? N ILE B 715 O GLN B 707 ? O GLN B 727 M 1 2 N THR B 468 ? N THR B 488 O ILE B 486 ? O ILE B 506 M 2 3 O GLY B 487 ? O GLY B 507 N THR B 479 ? N THR B 499 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CU A 801' AC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 802' AC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 803' AC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL A 804' AC5 Software ? ? ? ? 16 'BINDING SITE FOR RESIDUE PNT A 901' AC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 1101' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 1102' AC8 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE BMA A 1103' AC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 5381' BC1 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 5382' BC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 7451' BC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 7452' BC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CU B 801' BC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA B 802' BC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA B 803' BC7 Software ? ? ? ? 14 'BINDING SITE FOR RESIDUE PNT B 901' BC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 1101' BC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 1102' CC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 5381' CC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG B 5382' CC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 7451' CC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG B 7452' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 TPQ A 441 ? TPQ A 461 . ? 1_555 ? 2 AC1 4 HIS A 490 ? HIS A 510 . ? 1_555 ? 3 AC1 4 HIS A 492 ? HIS A 512 . ? 1_555 ? 4 AC1 4 HIS A 655 ? HIS A 675 . ? 1_555 ? 5 AC2 6 HOH Y . ? HOH A 20 . ? 1_555 ? 6 AC2 6 ASP A 499 ? ASP A 519 . ? 1_555 ? 7 AC2 6 LEU A 500 ? LEU A 520 . ? 1_555 ? 8 AC2 6 ASP A 501 ? ASP A 521 . ? 1_555 ? 9 AC2 6 ASP A 644 ? ASP A 664 . ? 1_555 ? 10 AC2 6 LEU A 645 ? LEU A 665 . ? 1_555 ? 11 AC3 6 GLU A 542 ? GLU A 562 . ? 1_555 ? 12 AC3 6 PHE A 633 ? PHE A 653 . ? 1_555 ? 13 AC3 6 ASN A 636 ? ASN A 656 . ? 1_555 ? 14 AC3 6 GLU A 638 ? GLU A 658 . ? 1_555 ? 15 AC3 6 HOH Y . ? HOH A 758 . ? 1_555 ? 16 AC3 6 HOH Y . ? HOH A 817 . ? 1_555 ? 17 AC4 7 GLU A 293 ? GLU A 313 . ? 1_555 ? 18 AC4 7 GLY A 294 ? GLY A 314 . ? 1_555 ? 19 AC4 7 TRP A 541 ? TRP A 561 . ? 3_455 ? 20 AC4 7 ASN A 637 ? ASN A 657 . ? 3_455 ? 21 AC4 7 HOH Y . ? HOH A 864 . ? 1_555 ? 22 AC4 7 HOH Y . ? HOH A 1047 . ? 1_555 ? 23 AC4 7 HOH Y . ? HOH A 1132 . ? 1_555 ? 24 AC5 16 TYR A 128 ? TYR A 148 . ? 1_555 ? 25 AC5 16 THR A 165 ? THR A 185 . ? 1_555 ? 26 AC5 16 ASP A 166 ? ASP A 186 . ? 1_555 ? 27 AC5 16 TYR A 351 ? TYR A 371 . ? 1_555 ? 28 AC5 16 ASP A 353 ? ASP A 373 . ? 1_555 ? 29 AC5 16 TRP A 356 ? TRP A 376 . ? 1_555 ? 30 AC5 16 GLY A 357 ? GLY A 377 . ? 1_555 ? 31 AC5 16 SER A 360 ? SER A 380 . ? 1_555 ? 32 AC5 16 VAL A 361 ? VAL A 381 . ? 1_555 ? 33 AC5 16 TYR A 384 ? TYR A 404 . ? 1_555 ? 34 AC5 16 VAL A 438 ? VAL A 458 . ? 1_555 ? 35 AC5 16 TYR A 439 ? TYR A 459 . ? 1_555 ? 36 AC5 16 ASN A 440 ? ASN A 460 . ? 1_555 ? 37 AC5 16 HOH Y . ? HOH A 885 . ? 1_555 ? 38 AC5 16 HOH Y . ? HOH A 936 . ? 1_555 ? 39 AC5 16 PHE B 415 ? PHE B 435 . ? 1_555 ? 40 AC6 4 GLN A 86 ? GLN A 106 . ? 1_555 ? 41 AC6 4 ASN A 90 ? ASN A 110 . ? 1_555 ? 42 AC6 4 THR A 92 ? THR A 112 . ? 1_555 ? 43 AC6 4 NAG I . ? NAG A 1102 . ? 1_555 ? 44 AC7 4 ARG A 699 ? ARG A 719 . ? 3_445 ? 45 AC7 4 HOH Y . ? HOH A 857 . ? 1_555 ? 46 AC7 4 NAG H . ? NAG A 1101 . ? 1_555 ? 47 AC7 4 BMA J . ? BMA A 1103 . ? 1_555 ? 48 AC8 4 ARG A 699 ? ARG A 719 . ? 3_445 ? 49 AC8 4 GLY A 702 ? GLY A 722 . ? 3_445 ? 50 AC8 4 HOH Y . ? HOH A 795 . ? 3_445 ? 51 AC8 4 NAG I . ? NAG A 1102 . ? 1_555 ? 52 AC9 4 ASN A 518 ? ASN A 538 . ? 1_555 ? 53 AC9 4 ARG A 528 ? ARG A 548 . ? 1_555 ? 54 AC9 4 NAG L . ? NAG A 5382 . ? 1_555 ? 55 AC9 4 TRP B 589 ? TRP B 609 . ? 1_555 ? 56 BC1 1 NAG K . ? NAG A 5381 . ? 1_555 ? 57 BC2 5 ASN A 725 ? ASN A 745 . ? 1_555 ? 58 BC2 5 HOH Y . ? HOH A 797 . ? 1_555 ? 59 BC2 5 NAG N . ? NAG A 7452 . ? 1_555 ? 60 BC2 5 ASN B 704 ? ASN B 724 . ? 1_555 ? 61 BC2 5 HOH Z . ? HOH B 1043 . ? 1_555 ? 62 BC3 1 NAG M . ? NAG A 7451 . ? 1_555 ? 63 BC4 4 TPQ B 441 ? TPQ B 461 . ? 1_555 ? 64 BC4 4 HIS B 490 ? HIS B 510 . ? 1_555 ? 65 BC4 4 HIS B 492 ? HIS B 512 . ? 1_555 ? 66 BC4 4 HIS B 655 ? HIS B 675 . ? 1_555 ? 67 BC5 6 ASP B 499 ? ASP B 519 . ? 1_555 ? 68 BC5 6 LEU B 500 ? LEU B 520 . ? 1_555 ? 69 BC5 6 ASP B 501 ? ASP B 521 . ? 1_555 ? 70 BC5 6 ASP B 644 ? ASP B 664 . ? 1_555 ? 71 BC5 6 LEU B 645 ? LEU B 665 . ? 1_555 ? 72 BC5 6 HOH Z . ? HOH B 876 . ? 1_555 ? 73 BC6 6 HOH Z . ? HOH B 5 . ? 1_555 ? 74 BC6 6 GLU B 542 ? GLU B 562 . ? 1_555 ? 75 BC6 6 PHE B 633 ? PHE B 653 . ? 1_555 ? 76 BC6 6 ASN B 636 ? ASN B 656 . ? 1_555 ? 77 BC6 6 GLU B 638 ? GLU B 658 . ? 1_555 ? 78 BC6 6 HOH Z . ? HOH B 834 . ? 1_555 ? 79 BC7 14 PHE A 415 ? PHE A 435 . ? 1_555 ? 80 BC7 14 TYR B 128 ? TYR B 148 . ? 1_555 ? 81 BC7 14 THR B 165 ? THR B 185 . ? 1_555 ? 82 BC7 14 ASP B 166 ? ASP B 186 . ? 1_555 ? 83 BC7 14 TYR B 351 ? TYR B 371 . ? 1_555 ? 84 BC7 14 ASP B 353 ? ASP B 373 . ? 1_555 ? 85 BC7 14 TRP B 356 ? TRP B 376 . ? 1_555 ? 86 BC7 14 GLY B 357 ? GLY B 377 . ? 1_555 ? 87 BC7 14 SER B 360 ? SER B 380 . ? 1_555 ? 88 BC7 14 VAL B 361 ? VAL B 381 . ? 1_555 ? 89 BC7 14 TYR B 384 ? TYR B 404 . ? 1_555 ? 90 BC7 14 TYR B 439 ? TYR B 459 . ? 1_555 ? 91 BC7 14 ASN B 440 ? ASN B 460 . ? 1_555 ? 92 BC7 14 HOH Z . ? HOH B 889 . ? 1_555 ? 93 BC8 5 GLN B 86 ? GLN B 106 . ? 1_555 ? 94 BC8 5 ASN B 90 ? ASN B 110 . ? 1_555 ? 95 BC8 5 THR B 92 ? THR B 112 . ? 1_555 ? 96 BC8 5 GLU B 237 ? GLU B 257 . ? 4_545 ? 97 BC8 5 NAG T . ? NAG B 1102 . ? 1_555 ? 98 BC9 4 LEU B 34 ? LEU B 54 . ? 1_555 ? 99 BC9 4 PHE B 83 ? PHE B 103 . ? 1_555 ? 100 BC9 4 PHE B 94 ? PHE B 114 . ? 1_555 ? 101 BC9 4 NAG S . ? NAG B 1101 . ? 1_555 ? 102 CC1 5 TRP A 589 ? TRP A 609 . ? 1_555 ? 103 CC1 5 ASN B 518 ? ASN B 538 . ? 1_555 ? 104 CC1 5 ARG B 528 ? ARG B 548 . ? 1_555 ? 105 CC1 5 HOH Z . ? HOH B 760 . ? 1_555 ? 106 CC1 5 NAG V . ? NAG B 5382 . ? 1_555 ? 107 CC2 3 HOH Z . ? HOH B 760 . ? 1_555 ? 108 CC2 3 HOH Z . ? HOH B 872 . ? 1_555 ? 109 CC2 3 NAG U . ? NAG B 5381 . ? 1_555 ? 110 CC3 5 ASN A 704 ? ASN A 724 . ? 1_555 ? 111 CC3 5 ASN B 725 ? ASN B 745 . ? 1_555 ? 112 CC3 5 HOH Z . ? HOH B 1033 . ? 1_555 ? 113 CC3 5 HOH Z . ? HOH B 1110 . ? 1_555 ? 114 CC3 5 NAG X . ? NAG B 7452 . ? 1_555 ? 115 CC4 1 NAG W . ? NAG B 7451 . ? 1_555 ? # _atom_sites.entry_id 3HII _atom_sites.fract_transf_matrix[1][1] 0.010816 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010561 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.005095 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CA CU N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . PRO A 1 7 ? -55.559 1.115 47.121 1.00 44.04 ? 27 PRO A N 1 ATOM 2 C CA . PRO A 1 7 ? -54.548 1.325 48.179 1.00 43.70 ? 27 PRO A CA 1 ATOM 3 C C . PRO A 1 7 ? -55.077 1.071 49.598 1.00 43.09 ? 27 PRO A C 1 ATOM 4 O O . PRO A 1 7 ? -54.300 0.693 50.488 1.00 43.56 ? 27 PRO A O 1 ATOM 5 C CB . PRO A 1 7 ? -54.142 2.798 48.001 1.00 43.79 ? 27 PRO A CB 1 ATOM 6 C CG . PRO A 1 7 ? -54.683 3.205 46.644 1.00 44.05 ? 27 PRO A CG 1 ATOM 7 C CD . PRO A 1 7 ? -55.917 2.376 46.452 1.00 44.18 ? 27 PRO A CD 1 ATOM 8 N N . ARG A 1 8 ? -56.379 1.292 49.803 1.00 41.99 ? 28 ARG A N 1 ATOM 9 C CA . ARG A 1 8 ? -57.064 0.913 51.046 1.00 41.03 ? 28 ARG A CA 1 ATOM 10 C C . ARG A 1 8 ? -57.125 -0.610 51.227 1.00 39.84 ? 28 ARG A C 1 ATOM 11 O O . ARG A 1 8 ? -57.218 -1.099 52.352 1.00 39.85 ? 28 ARG A O 1 ATOM 12 C CB . ARG A 1 8 ? -58.492 1.483 51.071 1.00 41.00 ? 28 ARG A CB 1 ATOM 13 N N . LYS A 1 9 ? -57.078 -1.349 50.119 1.00 38.37 ? 29 LYS A N 1 ATOM 14 C CA . LYS A 1 9 ? -57.077 -2.812 50.155 1.00 37.29 ? 29 LYS A CA 1 ATOM 15 C C . LYS A 1 9 ? -55.838 -3.405 50.828 1.00 35.86 ? 29 LYS A C 1 ATOM 16 O O . LYS A 1 9 ? -55.933 -4.453 51.460 1.00 36.10 ? 29 LYS A O 1 ATOM 17 C CB . LYS A 1 9 ? -57.216 -3.392 48.747 1.00 37.31 ? 29 LYS A CB 1 ATOM 18 C CG . LYS A 1 9 ? -58.561 -3.075 48.102 1.00 38.24 ? 29 LYS A CG 1 ATOM 19 C CD . LYS A 1 9 ? -59.058 -4.211 47.228 1.00 38.55 ? 29 LYS A CD 1 ATOM 20 C CE . LYS A 1 9 ? -60.532 -4.039 46.915 1.00 38.67 ? 29 LYS A CE 1 ATOM 21 N NZ . LYS A 1 9 ? -61.062 -5.204 46.167 1.00 39.14 ? 29 LYS A NZ 1 ATOM 22 N N . ALA A 1 10 ? -54.695 -2.736 50.700 1.00 33.83 ? 30 ALA A N 1 ATOM 23 C CA . ALA A 1 10 ? -53.451 -3.198 51.318 1.00 32.67 ? 30 ALA A CA 1 ATOM 24 C C . ALA A 1 10 ? -53.547 -3.285 52.847 1.00 31.20 ? 30 ALA A C 1 ATOM 25 O O . ALA A 1 10 ? -52.776 -4.002 53.469 1.00 31.12 ? 30 ALA A O 1 ATOM 26 C CB . ALA A 1 10 ? -52.268 -2.295 50.901 1.00 32.38 ? 30 ALA A CB 1 ATOM 27 N N . GLY A 1 11 ? -54.493 -2.547 53.431 1.00 29.84 ? 31 GLY A N 1 ATOM 28 C CA . GLY A 1 11 ? -54.805 -2.604 54.855 1.00 28.69 ? 31 GLY A CA 1 ATOM 29 C C . GLY A 1 11 ? -55.063 -3.999 55.406 1.00 27.66 ? 31 GLY A C 1 ATOM 30 O O . GLY A 1 11 ? -54.832 -4.247 56.585 1.00 27.04 ? 31 GLY A O 1 ATOM 31 N N . VAL A 1 12 ? -55.539 -4.909 54.557 1.00 26.70 ? 32 VAL A N 1 ATOM 32 C CA . VAL A 1 12 ? -55.747 -6.295 54.949 1.00 25.78 ? 32 VAL A CA 1 ATOM 33 C C . VAL A 1 12 ? -54.428 -6.943 55.414 1.00 25.00 ? 32 VAL A C 1 ATOM 34 O O . VAL A 1 12 ? -54.429 -7.779 56.309 1.00 24.18 ? 32 VAL A O 1 ATOM 35 C CB . VAL A 1 12 ? -56.408 -7.106 53.813 1.00 26.13 ? 32 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 12 ? -55.432 -7.325 52.668 1.00 25.95 ? 32 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 12 ? -56.967 -8.434 54.349 1.00 25.72 ? 32 VAL A CG2 1 ATOM 38 N N . PHE A 1 13 ? -53.310 -6.511 54.835 1.00 24.37 ? 33 PHE A N 1 ATOM 39 C CA . PHE A 1 13 ? -51.987 -7.023 55.194 1.00 23.85 ? 33 PHE A CA 1 ATOM 40 C C . PHE A 1 13 ? -51.300 -6.202 56.288 1.00 23.79 ? 33 PHE A C 1 ATOM 41 O O . PHE A 1 13 ? -50.189 -6.531 56.702 1.00 23.44 ? 33 PHE A O 1 ATOM 42 C CB . PHE A 1 13 ? -51.082 -7.046 53.959 1.00 23.66 ? 33 PHE A CB 1 ATOM 43 C CG . PHE A 1 13 ? -51.631 -7.847 52.809 1.00 22.53 ? 33 PHE A CG 1 ATOM 44 C CD1 . PHE A 1 13 ? -51.773 -9.221 52.910 1.00 21.77 ? 33 PHE A CD1 1 ATOM 45 C CD2 . PHE A 1 13 ? -51.978 -7.230 51.617 1.00 21.21 ? 33 PHE A CD2 1 ATOM 46 C CE1 . PHE A 1 13 ? -52.255 -9.962 51.850 1.00 20.65 ? 33 PHE A CE1 1 ATOM 47 C CE2 . PHE A 1 13 ? -52.478 -7.967 50.558 1.00 21.16 ? 33 PHE A CE2 1 ATOM 48 C CZ . PHE A 1 13 ? -52.612 -9.338 50.671 1.00 20.93 ? 33 PHE A CZ 1 ATOM 49 N N . SER A 1 14 ? -51.956 -5.147 56.759 1.00 23.72 ? 34 SER A N 1 ATOM 50 C CA . SER A 1 14 ? -51.314 -4.188 57.647 1.00 24.35 ? 34 SER A CA 1 ATOM 51 C C . SER A 1 14 ? -51.192 -4.648 59.089 1.00 24.46 ? 34 SER A C 1 ATOM 52 O O . SER A 1 14 ? -52.070 -5.312 59.631 1.00 24.52 ? 34 SER A O 1 ATOM 53 C CB . SER A 1 14 ? -52.055 -2.850 57.629 1.00 24.15 ? 34 SER A CB 1 ATOM 54 O OG . SER A 1 14 ? -53.299 -2.966 58.290 1.00 25.38 ? 34 SER A OG 1 ATOM 55 N N . ASP A 1 15 ? -50.093 -4.248 59.711 1.00 24.78 ? 35 ASP A N 1 ATOM 56 C CA . ASP A 1 15 ? -49.869 -4.495 61.120 1.00 24.92 ? 35 ASP A CA 1 ATOM 57 C C . ASP A 1 15 ? -50.887 -3.774 61.987 1.00 24.73 ? 35 ASP A C 1 ATOM 58 O O . ASP A 1 15 ? -51.551 -2.845 61.553 1.00 24.43 ? 35 ASP A O 1 ATOM 59 C CB . ASP A 1 15 ? -48.462 -4.044 61.511 1.00 25.15 ? 35 ASP A CB 1 ATOM 60 C CG . ASP A 1 15 ? -47.401 -4.948 60.959 1.00 25.84 ? 35 ASP A CG 1 ATOM 61 O OD1 . ASP A 1 15 ? -47.529 -6.183 61.127 1.00 28.56 ? 35 ASP A OD1 1 ATOM 62 O OD2 . ASP A 1 15 ? -46.447 -4.431 60.353 1.00 24.79 ? 35 ASP A OD2 1 ATOM 63 N N . LEU A 1 16 ? -51.001 -4.223 63.227 1.00 24.91 ? 36 LEU A N 1 ATOM 64 C CA . LEU A 1 16 ? -51.910 -3.608 64.174 1.00 24.85 ? 36 LEU A CA 1 ATOM 65 C C . LEU A 1 16 ? -51.393 -2.217 64.555 1.00 25.17 ? 36 LEU A C 1 ATOM 66 O O . LEU A 1 16 ? -50.189 -2.034 64.752 1.00 24.67 ? 36 LEU A O 1 ATOM 67 C CB . LEU A 1 16 ? -52.034 -4.477 65.423 1.00 24.81 ? 36 LEU A CB 1 ATOM 68 C CG . LEU A 1 16 ? -52.576 -5.894 65.227 1.00 24.21 ? 36 LEU A CG 1 ATOM 69 C CD1 . LEU A 1 16 ? -52.552 -6.657 66.550 1.00 23.13 ? 36 LEU A CD1 1 ATOM 70 C CD2 . LEU A 1 16 ? -53.981 -5.879 64.610 1.00 22.66 ? 36 LEU A CD2 1 ATOM 71 N N . SER A 1 17 ? -52.310 -1.250 64.647 1.00 25.10 ? 37 SER A N 1 ATOM 72 C CA . SER A 1 17 ? -51.988 0.096 65.123 1.00 25.07 ? 37 SER A CA 1 ATOM 73 C C . SER A 1 17 ? -51.836 0.097 66.630 1.00 24.94 ? 37 SER A C 1 ATOM 74 O O . SER A 1 17 ? -52.265 -0.842 67.300 1.00 24.03 ? 37 SER A O 1 ATOM 75 C CB . SER A 1 17 ? -53.109 1.065 64.775 1.00 25.09 ? 37 SER A CB 1 ATOM 76 O OG . SER A 1 17 ? -54.306 0.708 65.466 1.00 26.54 ? 37 SER A OG 1 ATOM 77 N N . ASN A 1 18 ? -51.260 1.178 67.154 1.00 24.95 ? 38 ASN A N 1 ATOM 78 C CA . ASN A 1 18 ? -51.203 1.411 68.598 1.00 25.29 ? 38 ASN A CA 1 ATOM 79 C C . ASN A 1 18 ? -52.595 1.266 69.236 1.00 25.43 ? 38 ASN A C 1 ATOM 80 O O . ASN A 1 18 ? -52.750 0.600 70.261 1.00 25.32 ? 38 ASN A O 1 ATOM 81 C CB . ASN A 1 18 ? -50.610 2.795 68.880 1.00 25.50 ? 38 ASN A CB 1 ATOM 82 C CG . ASN A 1 18 ? -50.300 3.021 70.344 1.00 25.84 ? 38 ASN A CG 1 ATOM 83 O OD1 . ASN A 1 18 ? -50.059 2.084 71.103 1.00 26.99 ? 38 ASN A OD1 1 ATOM 84 N ND2 . ASN A 1 18 ? -50.287 4.282 70.746 1.00 27.42 ? 38 ASN A ND2 1 ATOM 85 N N . GLN A 1 19 ? -53.606 1.846 68.592 1.00 25.60 ? 39 GLN A N 1 ATOM 86 C CA . GLN A 1 19 ? -54.993 1.749 69.060 1.00 26.04 ? 39 GLN A CA 1 ATOM 87 C C . GLN A 1 19 ? -55.511 0.307 69.122 1.00 25.98 ? 39 GLN A C 1 ATOM 88 O O . GLN A 1 19 ? -56.112 -0.103 70.109 1.00 26.31 ? 39 GLN A O 1 ATOM 89 C CB . GLN A 1 19 ? -55.919 2.583 68.162 1.00 26.06 ? 39 GLN A CB 1 ATOM 90 N N . GLU A 1 20 ? -55.284 -0.451 68.058 1.00 26.34 ? 40 GLU A N 1 ATOM 91 C CA . GLU A 1 20 ? -55.738 -1.843 67.989 1.00 25.97 ? 40 GLU A CA 1 ATOM 92 C C . GLU A 1 20 ? -55.021 -2.743 68.999 1.00 25.89 ? 40 GLU A C 1 ATOM 93 O O . GLU A 1 20 ? -55.647 -3.608 69.612 1.00 25.83 ? 40 GLU A O 1 ATOM 94 C CB . GLU A 1 20 ? -55.546 -2.399 66.585 1.00 26.34 ? 40 GLU A CB 1 ATOM 95 C CG . GLU A 1 20 ? -56.471 -1.819 65.533 1.00 25.68 ? 40 GLU A CG 1 ATOM 96 C CD . GLU A 1 20 ? -56.093 -2.276 64.135 1.00 26.24 ? 40 GLU A CD 1 ATOM 97 O OE1 . GLU A 1 20 ? -54.892 -2.198 63.784 1.00 26.45 ? 40 GLU A OE1 1 ATOM 98 O OE2 . GLU A 1 20 ? -56.989 -2.716 63.385 1.00 25.13 ? 40 GLU A OE2 1 ATOM 99 N N . LEU A 1 21 ? -53.717 -2.541 69.171 1.00 25.56 ? 41 LEU A N 1 ATOM 100 C CA . LEU A 1 21 ? -52.969 -3.275 70.173 1.00 25.55 ? 41 LEU A CA 1 ATOM 101 C C . LEU A 1 21 ? -53.602 -3.049 71.557 1.00 26.08 ? 41 LEU A C 1 ATOM 102 O O . LEU A 1 21 ? -53.849 -4.007 72.301 1.00 25.70 ? 41 LEU A O 1 ATOM 103 C CB . LEU A 1 21 ? -51.493 -2.853 70.172 1.00 25.18 ? 41 LEU A CB 1 ATOM 104 C CG . LEU A 1 21 ? -50.641 -3.281 68.966 1.00 24.96 ? 41 LEU A CG 1 ATOM 105 C CD1 . LEU A 1 21 ? -49.348 -2.479 68.904 1.00 24.12 ? 41 LEU A CD1 1 ATOM 106 C CD2 . LEU A 1 21 ? -50.337 -4.774 69.012 1.00 23.36 ? 41 LEU A CD2 1 ATOM 107 N N . LYS A 1 22 ? -53.863 -1.784 71.888 1.00 26.44 ? 42 LYS A N 1 ATOM 108 C CA . LYS A 1 22 ? -54.501 -1.429 73.158 1.00 26.91 ? 42 LYS A CA 1 ATOM 109 C C . LYS A 1 22 ? -55.882 -2.053 73.282 1.00 27.13 ? 42 LYS A C 1 ATOM 110 O O . LYS A 1 22 ? -56.243 -2.534 74.353 1.00 27.44 ? 42 LYS A O 1 ATOM 111 C CB . LYS A 1 22 ? -54.631 0.090 73.318 1.00 26.87 ? 42 LYS A CB 1 ATOM 112 C CG . LYS A 1 22 ? -53.336 0.812 73.609 1.00 27.69 ? 42 LYS A CG 1 ATOM 113 C CD . LYS A 1 22 ? -53.547 2.329 73.625 1.00 28.73 ? 42 LYS A CD 1 ATOM 114 C CE . LYS A 1 22 ? -52.222 3.082 73.785 1.00 29.26 ? 42 LYS A CE 1 ATOM 115 N NZ . LYS A 1 22 ? -52.355 4.537 73.443 1.00 29.41 ? 42 LYS A NZ 1 ATOM 116 N N . ALA A 1 23 ? -56.650 -2.036 72.196 1.00 27.20 ? 43 ALA A N 1 ATOM 117 C CA . ALA A 1 23 ? -57.995 -2.612 72.205 1.00 27.55 ? 43 ALA A CA 1 ATOM 118 C C . ALA A 1 23 ? -57.972 -4.111 72.491 1.00 28.18 ? 43 ALA A C 1 ATOM 119 O O . ALA A 1 23 ? -58.849 -4.622 73.190 1.00 28.10 ? 43 ALA A O 1 ATOM 120 C CB . ALA A 1 23 ? -58.707 -2.339 70.885 1.00 27.13 ? 43 ALA A CB 1 ATOM 121 N N . VAL A 1 24 ? -56.985 -4.811 71.929 1.00 28.48 ? 44 VAL A N 1 ATOM 122 C CA . VAL A 1 24 ? -56.835 -6.246 72.153 1.00 29.07 ? 44 VAL A CA 1 ATOM 123 C C . VAL A 1 24 ? -56.383 -6.506 73.588 1.00 29.75 ? 44 VAL A C 1 ATOM 124 O O . VAL A 1 24 ? -56.936 -7.361 74.274 1.00 30.12 ? 44 VAL A O 1 ATOM 125 C CB . VAL A 1 24 ? -55.832 -6.905 71.154 1.00 29.12 ? 44 VAL A CB 1 ATOM 126 C CG1 . VAL A 1 24 ? -55.473 -8.316 71.604 1.00 28.59 ? 44 VAL A CG1 1 ATOM 127 C CG2 . VAL A 1 24 ? -56.412 -6.927 69.726 1.00 28.83 ? 44 VAL A CG2 1 ATOM 128 N N . HIS A 1 25 ? -55.387 -5.753 74.034 1.00 30.35 ? 45 HIS A N 1 ATOM 129 C CA . HIS A 1 25 ? -54.875 -5.880 75.382 1.00 31.45 ? 45 HIS A CA 1 ATOM 130 C C . HIS A 1 25 ? -55.960 -5.603 76.431 1.00 31.59 ? 45 HIS A C 1 ATOM 131 O O . HIS A 1 25 ? -56.047 -6.314 77.433 1.00 31.18 ? 45 HIS A O 1 ATOM 132 C CB . HIS A 1 25 ? -53.693 -4.932 75.579 1.00 31.84 ? 45 HIS A CB 1 ATOM 133 C CG . HIS A 1 25 ? -52.917 -5.195 76.826 1.00 34.47 ? 45 HIS A CG 1 ATOM 134 N ND1 . HIS A 1 25 ? -52.337 -4.190 77.566 1.00 38.26 ? 45 HIS A ND1 1 ATOM 135 C CD2 . HIS A 1 25 ? -52.631 -6.350 77.470 1.00 37.02 ? 45 HIS A CD2 1 ATOM 136 C CE1 . HIS A 1 25 ? -51.720 -4.715 78.610 1.00 38.48 ? 45 HIS A CE1 1 ATOM 137 N NE2 . HIS A 1 25 ? -51.883 -6.025 78.573 1.00 37.97 ? 45 HIS A NE2 1 ATOM 138 N N . SER A 1 26 ? -56.775 -4.575 76.185 1.00 31.79 ? 46 SER A N 1 ATOM 139 C CA A SER A 1 26 ? -57.874 -4.218 77.093 0.50 31.96 ? 46 SER A CA 1 ATOM 140 C CA B SER A 1 26 ? -57.881 -4.207 77.076 0.50 32.02 ? 46 SER A CA 1 ATOM 141 C C . SER A 1 26 ? -58.924 -5.317 77.150 1.00 32.03 ? 46 SER A C 1 ATOM 142 O O . SER A 1 26 ? -59.423 -5.650 78.228 1.00 32.09 ? 46 SER A O 1 ATOM 143 C CB A SER A 1 26 ? -58.541 -2.905 76.672 0.50 32.00 ? 46 SER A CB 1 ATOM 144 C CB B SER A 1 26 ? -58.538 -2.909 76.590 0.50 32.08 ? 46 SER A CB 1 ATOM 145 O OG A SER A 1 26 ? -57.719 -1.796 76.977 0.50 31.99 ? 46 SER A OG 1 ATOM 146 O OG B SER A 1 26 ? -59.843 -2.759 77.113 0.50 32.39 ? 46 SER A OG 1 ATOM 147 N N . PHE A 1 27 ? -59.259 -5.873 75.989 1.00 32.06 ? 47 PHE A N 1 ATOM 148 C CA . PHE A 1 27 ? -60.205 -6.972 75.912 1.00 32.18 ? 47 PHE A CA 1 ATOM 149 C C . PHE A 1 27 ? -59.708 -8.182 76.705 1.00 32.40 ? 47 PHE A C 1 ATOM 150 O O . PHE A 1 27 ? -60.475 -8.803 77.441 1.00 32.50 ? 47 PHE A O 1 ATOM 151 C CB . PHE A 1 27 ? -60.457 -7.354 74.457 1.00 32.03 ? 47 PHE A CB 1 ATOM 152 C CG . PHE A 1 27 ? -61.248 -8.620 74.289 1.00 32.03 ? 47 PHE A CG 1 ATOM 153 C CD1 . PHE A 1 27 ? -62.630 -8.612 74.417 1.00 32.53 ? 47 PHE A CD1 1 ATOM 154 C CD2 . PHE A 1 27 ? -60.612 -9.818 73.990 1.00 31.24 ? 47 PHE A CD2 1 ATOM 155 C CE1 . PHE A 1 27 ? -63.360 -9.778 74.266 1.00 32.13 ? 47 PHE A CE1 1 ATOM 156 C CE2 . PHE A 1 27 ? -61.330 -10.981 73.836 1.00 31.07 ? 47 PHE A CE2 1 ATOM 157 C CZ . PHE A 1 27 ? -62.710 -10.964 73.972 1.00 32.18 ? 47 PHE A CZ 1 ATOM 158 N N . LEU A 1 28 ? -58.428 -8.513 76.570 1.00 32.66 ? 48 LEU A N 1 ATOM 159 C CA . LEU A 1 28 ? -57.869 -9.623 77.340 1.00 32.95 ? 48 LEU A CA 1 ATOM 160 C C . LEU A 1 28 ? -57.935 -9.320 78.839 1.00 33.56 ? 48 LEU A C 1 ATOM 161 O O . LEU A 1 28 ? -58.355 -10.167 79.634 1.00 33.36 ? 48 LEU A O 1 ATOM 162 C CB . LEU A 1 28 ? -56.439 -9.953 76.892 1.00 32.90 ? 48 LEU A CB 1 ATOM 163 C CG . LEU A 1 28 ? -56.330 -10.557 75.477 1.00 32.37 ? 48 LEU A CG 1 ATOM 164 C CD1 . LEU A 1 28 ? -54.871 -10.694 75.043 1.00 31.00 ? 48 LEU A CD1 1 ATOM 165 C CD2 . LEU A 1 28 ? -57.039 -11.900 75.392 1.00 29.77 ? 48 LEU A CD2 1 ATOM 166 N N . TRP A 1 29 ? -57.556 -8.104 79.217 1.00 34.35 ? 49 TRP A N 1 ATOM 167 C CA . TRP A 1 29 ? -57.629 -7.686 80.621 1.00 35.29 ? 49 TRP A CA 1 ATOM 168 C C . TRP A 1 29 ? -59.056 -7.633 81.205 1.00 35.59 ? 49 TRP A C 1 ATOM 169 O O . TRP A 1 29 ? -59.219 -7.769 82.411 1.00 35.80 ? 49 TRP A O 1 ATOM 170 C CB . TRP A 1 29 ? -56.902 -6.352 80.830 1.00 35.43 ? 49 TRP A CB 1 ATOM 171 C CG . TRP A 1 29 ? -55.459 -6.566 81.094 1.00 37.02 ? 49 TRP A CG 1 ATOM 172 C CD1 . TRP A 1 29 ? -54.557 -7.170 80.262 1.00 38.58 ? 49 TRP A CD1 1 ATOM 173 C CD2 . TRP A 1 29 ? -54.745 -6.231 82.283 1.00 37.96 ? 49 TRP A CD2 1 ATOM 174 N NE1 . TRP A 1 29 ? -53.320 -7.217 80.859 1.00 39.50 ? 49 TRP A NE1 1 ATOM 175 C CE2 . TRP A 1 29 ? -53.405 -6.649 82.099 1.00 38.24 ? 49 TRP A CE2 1 ATOM 176 C CE3 . TRP A 1 29 ? -55.102 -5.610 83.485 1.00 39.05 ? 49 TRP A CE3 1 ATOM 177 C CZ2 . TRP A 1 29 ? -52.421 -6.464 83.067 1.00 39.14 ? 49 TRP A CZ2 1 ATOM 178 C CZ3 . TRP A 1 29 ? -54.124 -5.426 84.450 1.00 39.51 ? 49 TRP A CZ3 1 ATOM 179 C CH2 . TRP A 1 29 ? -52.795 -5.853 84.235 1.00 39.77 ? 49 TRP A CH2 1 ATOM 180 N N . SER A 1 30 ? -60.076 -7.468 80.364 1.00 36.04 ? 50 SER A N 1 ATOM 181 C CA . SER A 1 30 ? -61.464 -7.439 80.843 1.00 36.41 ? 50 SER A CA 1 ATOM 182 C C . SER A 1 30 ? -61.990 -8.830 81.230 1.00 37.20 ? 50 SER A C 1 ATOM 183 O O . SER A 1 30 ? -63.016 -8.934 81.907 1.00 37.45 ? 50 SER A O 1 ATOM 184 C CB . SER A 1 30 ? -62.392 -6.790 79.807 1.00 36.31 ? 50 SER A CB 1 ATOM 185 O OG . SER A 1 30 ? -62.726 -7.677 78.753 1.00 35.81 ? 50 SER A OG 1 ATOM 186 N N . LYS A 1 31 ? -61.307 -9.890 80.784 1.00 37.60 ? 51 LYS A N 1 ATOM 187 C CA . LYS A 1 31 ? -61.635 -11.256 81.192 1.00 37.78 ? 51 LYS A CA 1 ATOM 188 C C . LYS A 1 31 ? -60.933 -11.563 82.517 1.00 37.63 ? 51 LYS A C 1 ATOM 189 O O . LYS A 1 31 ? -59.795 -12.036 82.537 1.00 37.49 ? 51 LYS A O 1 ATOM 190 C CB . LYS A 1 31 ? -61.217 -12.267 80.121 1.00 37.94 ? 51 LYS A CB 1 ATOM 191 C CG . LYS A 1 31 ? -61.747 -11.991 78.722 1.00 38.90 ? 51 LYS A CG 1 ATOM 192 C CD . LYS A 1 31 ? -63.257 -11.927 78.686 1.00 40.51 ? 51 LYS A CD 1 ATOM 193 C CE . LYS A 1 31 ? -63.776 -11.847 77.259 1.00 41.21 ? 51 LYS A CE 1 ATOM 194 N NZ . LYS A 1 31 ? -65.235 -11.514 77.214 1.00 41.40 ? 51 LYS A NZ 1 ATOM 195 N N . LYS A 1 32 ? -61.622 -11.285 83.625 1.00 37.52 ? 52 LYS A N 1 ATOM 196 C CA . LYS A 1 32 ? -61.026 -11.395 84.971 1.00 37.30 ? 52 LYS A CA 1 ATOM 197 C C . LYS A 1 32 ? -60.534 -12.802 85.312 1.00 36.75 ? 52 LYS A C 1 ATOM 198 O O . LYS A 1 32 ? -59.616 -12.967 86.118 1.00 36.39 ? 52 LYS A O 1 ATOM 199 C CB . LYS A 1 32 ? -62.020 -10.929 86.048 1.00 37.59 ? 52 LYS A CB 1 ATOM 200 C CG . LYS A 1 32 ? -61.904 -9.458 86.430 1.00 38.00 ? 52 LYS A CG 1 ATOM 201 C CD . LYS A 1 32 ? -61.966 -8.544 85.216 1.00 39.40 ? 52 LYS A CD 1 ATOM 202 N N . GLU A 1 33 ? -61.139 -13.815 84.699 1.00 36.43 ? 53 GLU A N 1 ATOM 203 C CA . GLU A 1 33 ? -60.737 -15.195 84.952 1.00 36.22 ? 53 GLU A CA 1 ATOM 204 C C . GLU A 1 33 ? -59.320 -15.535 84.456 1.00 35.58 ? 53 GLU A C 1 ATOM 205 O O . GLU A 1 33 ? -58.752 -16.537 84.875 1.00 35.33 ? 53 GLU A O 1 ATOM 206 C CB . GLU A 1 33 ? -61.769 -16.179 84.384 1.00 36.39 ? 53 GLU A CB 1 ATOM 207 C CG . GLU A 1 33 ? -61.747 -16.360 82.877 1.00 38.16 ? 53 GLU A CG 1 ATOM 208 C CD . GLU A 1 33 ? -62.491 -15.274 82.114 1.00 39.35 ? 53 GLU A CD 1 ATOM 209 O OE1 . GLU A 1 33 ? -62.874 -14.238 82.713 1.00 39.33 ? 53 GLU A OE1 1 ATOM 210 O OE2 . GLU A 1 33 ? -62.683 -15.477 80.897 1.00 40.71 ? 53 GLU A OE2 1 ATOM 211 N N . LEU A 1 34 ? -58.754 -14.709 83.574 1.00 34.91 ? 54 LEU A N 1 ATOM 212 C CA . LEU A 1 34 ? -57.391 -14.930 83.077 1.00 34.36 ? 54 LEU A CA 1 ATOM 213 C C . LEU A 1 34 ? -56.339 -14.498 84.090 1.00 34.19 ? 54 LEU A C 1 ATOM 214 O O . LEU A 1 34 ? -55.167 -14.861 83.953 1.00 33.94 ? 54 LEU A O 1 ATOM 215 C CB . LEU A 1 34 ? -57.168 -14.190 81.753 1.00 34.21 ? 54 LEU A CB 1 ATOM 216 C CG . LEU A 1 34 ? -58.071 -14.630 80.600 1.00 33.97 ? 54 LEU A CG 1 ATOM 217 C CD1 . LEU A 1 34 ? -57.898 -13.716 79.387 1.00 33.04 ? 54 LEU A CD1 1 ATOM 218 C CD2 . LEU A 1 34 ? -57.814 -16.092 80.229 1.00 32.80 ? 54 LEU A CD2 1 ATOM 219 N N . ARG A 1 35 ? -56.754 -13.718 85.095 1.00 33.94 ? 55 ARG A N 1 ATOM 220 C CA . ARG A 1 35 ? -55.865 -13.282 86.175 1.00 33.88 ? 55 ARG A CA 1 ATOM 221 C C . ARG A 1 35 ? -54.563 -12.680 85.629 1.00 33.57 ? 55 ARG A C 1 ATOM 222 O O . ARG A 1 35 ? -53.465 -12.995 86.102 1.00 33.12 ? 55 ARG A O 1 ATOM 223 C CB . ARG A 1 35 ? -55.560 -14.459 87.117 1.00 34.13 ? 55 ARG A CB 1 ATOM 224 C CG . ARG A 1 35 ? -56.777 -15.033 87.833 1.00 35.20 ? 55 ARG A CG 1 ATOM 225 C CD . ARG A 1 35 ? -56.490 -16.413 88.435 1.00 36.77 ? 55 ARG A CD 1 ATOM 226 N NE . ARG A 1 35 ? -55.213 -16.459 89.148 1.00 37.43 ? 55 ARG A NE 1 ATOM 227 N N . LEU A 1 36 ? -54.697 -11.807 84.634 1.00 33.46 ? 56 LEU A N 1 ATOM 228 C CA . LEU A 1 36 ? -53.538 -11.295 83.905 1.00 33.45 ? 56 LEU A CA 1 ATOM 229 C C . LEU A 1 36 ? -52.799 -10.240 84.710 1.00 33.68 ? 56 LEU A C 1 ATOM 230 O O . LEU A 1 36 ? -53.422 -9.370 85.305 1.00 34.27 ? 56 LEU A O 1 ATOM 231 C CB . LEU A 1 36 ? -53.952 -10.720 82.550 1.00 33.03 ? 56 LEU A CB 1 ATOM 232 C CG . LEU A 1 36 ? -54.414 -11.740 81.513 1.00 32.47 ? 56 LEU A CG 1 ATOM 233 C CD1 . LEU A 1 36 ? -55.064 -11.039 80.312 1.00 31.08 ? 56 LEU A CD1 1 ATOM 234 C CD2 . LEU A 1 36 ? -53.249 -12.614 81.077 1.00 31.60 ? 56 LEU A CD2 1 ATOM 235 N N . GLN A 1 37 ? -51.470 -10.334 84.718 1.00 33.54 ? 57 GLN A N 1 ATOM 236 C CA . GLN A 1 37 ? -50.607 -9.351 85.356 1.00 33.41 ? 57 GLN A CA 1 ATOM 237 C C . GLN A 1 37 ? -49.666 -8.730 84.327 1.00 33.68 ? 57 GLN A C 1 ATOM 238 O O . GLN A 1 37 ? -49.501 -9.276 83.230 1.00 33.47 ? 57 GLN A O 1 ATOM 239 C CB . GLN A 1 37 ? -49.804 -10.015 86.467 1.00 33.45 ? 57 GLN A CB 1 ATOM 240 C CG . GLN A 1 37 ? -50.682 -10.508 87.602 1.00 33.30 ? 57 GLN A CG 1 ATOM 241 C CD . GLN A 1 37 ? -49.897 -11.176 88.694 1.00 32.60 ? 57 GLN A CD 1 ATOM 242 O OE1 . GLN A 1 37 ? -48.991 -10.583 89.271 1.00 34.08 ? 57 GLN A OE1 1 ATOM 243 N NE2 . GLN A 1 37 ? -50.243 -12.421 88.992 1.00 33.10 ? 57 GLN A NE2 1 ATOM 244 N N . PRO A 1 38 ? -49.051 -7.583 84.670 1.00 33.70 ? 58 PRO A N 1 ATOM 245 C CA . PRO A 1 38 ? -48.101 -6.960 83.756 1.00 33.71 ? 58 PRO A CA 1 ATOM 246 C C . PRO A 1 38 ? -46.851 -7.810 83.550 1.00 33.85 ? 58 PRO A C 1 ATOM 247 O O . PRO A 1 38 ? -46.429 -8.530 84.463 1.00 33.37 ? 58 PRO A O 1 ATOM 248 C CB . PRO A 1 38 ? -47.740 -5.634 84.451 1.00 33.94 ? 58 PRO A CB 1 ATOM 249 C CG . PRO A 1 38 ? -48.791 -5.406 85.487 1.00 33.73 ? 58 PRO A CG 1 ATOM 250 C CD . PRO A 1 38 ? -49.260 -6.774 85.888 1.00 33.94 ? 58 PRO A CD 1 ATOM 251 N N . SER A 1 39 ? -46.262 -7.703 82.359 1.00 34.08 ? 59 SER A N 1 ATOM 252 C CA . SER A 1 39 ? -45.100 -8.506 81.985 1.00 34.57 ? 59 SER A CA 1 ATOM 253 C C . SER A 1 39 ? -43.904 -8.222 82.883 1.00 34.79 ? 59 SER A C 1 ATOM 254 O O . SER A 1 39 ? -43.080 -9.105 83.122 1.00 35.09 ? 59 SER A O 1 ATOM 255 C CB . SER A 1 39 ? -44.715 -8.258 80.520 1.00 34.78 ? 59 SER A CB 1 ATOM 256 O OG . SER A 1 39 ? -44.007 -7.033 80.365 1.00 35.52 ? 59 SER A OG 1 ATOM 257 N N . SER A 1 40 ? -43.825 -6.994 83.392 1.00 34.96 ? 60 SER A N 1 ATOM 258 C CA . SER A 1 40 ? -42.728 -6.583 84.252 1.00 35.00 ? 60 SER A CA 1 ATOM 259 C C . SER A 1 40 ? -42.819 -7.115 85.683 1.00 35.03 ? 60 SER A C 1 ATOM 260 O O . SER A 1 40 ? -41.865 -6.970 86.440 1.00 35.57 ? 60 SER A O 1 ATOM 261 C CB . SER A 1 40 ? -42.633 -5.054 84.288 1.00 35.15 ? 60 SER A CB 1 ATOM 262 O OG . SER A 1 40 ? -43.817 -4.474 84.813 1.00 35.60 ? 60 SER A OG 1 ATOM 263 N N . THR A 1 41 ? -43.948 -7.707 86.069 1.00 34.73 ? 61 THR A N 1 ATOM 264 C CA . THR A 1 41 ? -44.051 -8.340 87.386 1.00 34.62 ? 61 THR A CA 1 ATOM 265 C C . THR A 1 41 ? -42.990 -9.438 87.502 1.00 34.64 ? 61 THR A C 1 ATOM 266 O O . THR A 1 41 ? -42.975 -10.373 86.695 1.00 34.40 ? 61 THR A O 1 ATOM 267 C CB . THR A 1 41 ? -45.433 -8.987 87.611 1.00 34.72 ? 61 THR A CB 1 ATOM 268 O OG1 . THR A 1 41 ? -46.467 -8.056 87.278 1.00 35.26 ? 61 THR A OG1 1 ATOM 269 C CG2 . THR A 1 41 ? -45.586 -9.439 89.063 1.00 33.89 ? 61 THR A CG2 1 ATOM 270 N N . THR A 1 42 ? -42.124 -9.338 88.508 1.00 34.64 ? 62 THR A N 1 ATOM 271 C CA . THR A 1 42 ? -40.952 -10.221 88.607 1.00 34.79 ? 62 THR A CA 1 ATOM 272 C C . THR A 1 42 ? -41.231 -11.528 89.353 1.00 34.20 ? 62 THR A C 1 ATOM 273 O O . THR A 1 42 ? -40.612 -11.831 90.377 1.00 34.64 ? 62 THR A O 1 ATOM 274 C CB . THR A 1 42 ? -39.740 -9.493 89.241 1.00 34.95 ? 62 THR A CB 1 ATOM 275 O OG1 . THR A 1 42 ? -40.169 -8.758 90.392 1.00 36.14 ? 62 THR A OG1 1 ATOM 276 C CG2 . THR A 1 42 ? -39.101 -8.530 88.234 1.00 35.89 ? 62 THR A CG2 1 ATOM 277 N N . THR A 1 43 ? -42.174 -12.296 88.819 1.00 33.41 ? 63 THR A N 1 ATOM 278 C CA . THR A 1 43 ? -42.376 -13.689 89.205 1.00 32.24 ? 63 THR A CA 1 ATOM 279 C C . THR A 1 43 ? -42.724 -14.465 87.939 1.00 31.59 ? 63 THR A C 1 ATOM 280 O O . THR A 1 43 ? -43.396 -13.933 87.049 1.00 31.37 ? 63 THR A O 1 ATOM 281 C CB . THR A 1 43 ? -43.516 -13.856 90.243 1.00 32.16 ? 63 THR A CB 1 ATOM 282 O OG1 . THR A 1 43 ? -43.701 -15.250 90.530 1.00 32.03 ? 63 THR A OG1 1 ATOM 283 C CG2 . THR A 1 43 ? -44.825 -13.276 89.727 1.00 30.87 ? 63 THR A CG2 1 ATOM 284 N N . MET A 1 44 ? -42.270 -15.710 87.863 1.00 30.67 ? 64 MET A N 1 ATOM 285 C CA . MET A 1 44 ? -42.636 -16.592 86.759 1.00 30.28 ? 64 MET A CA 1 ATOM 286 C C . MET A 1 44 ? -44.053 -17.151 86.932 1.00 29.94 ? 64 MET A C 1 ATOM 287 O O . MET A 1 44 ? -44.732 -17.471 85.949 1.00 29.02 ? 64 MET A O 1 ATOM 288 C CB . MET A 1 44 ? -41.632 -17.741 86.632 1.00 30.34 ? 64 MET A CB 1 ATOM 289 C CG . MET A 1 44 ? -40.178 -17.316 86.423 1.00 30.19 ? 64 MET A CG 1 ATOM 290 S SD . MET A 1 44 ? -39.804 -16.575 84.817 1.00 30.37 ? 64 MET A SD 1 ATOM 291 C CE . MET A 1 44 ? -40.468 -14.909 85.001 1.00 30.37 ? 64 MET A CE 1 ATOM 292 N N . ALA A 1 45 ? -44.507 -17.258 88.179 1.00 29.62 ? 65 ALA A N 1 ATOM 293 C CA . ALA A 1 45 ? -45.812 -17.830 88.459 1.00 29.74 ? 65 ALA A CA 1 ATOM 294 C C . ALA A 1 45 ? -46.870 -16.746 88.319 1.00 29.63 ? 65 ALA A C 1 ATOM 295 O O . ALA A 1 45 ? -47.498 -16.358 89.291 1.00 30.11 ? 65 ALA A O 1 ATOM 296 C CB . ALA A 1 45 ? -45.844 -18.472 89.862 1.00 29.46 ? 65 ALA A CB 1 ATOM 297 N N . LYS A 1 46 ? -47.061 -16.278 87.089 1.00 29.57 ? 66 LYS A N 1 ATOM 298 C CA . LYS A 1 46 ? -48.049 -15.256 86.761 1.00 29.19 ? 66 LYS A CA 1 ATOM 299 C C . LYS A 1 46 ? -48.643 -15.571 85.398 1.00 28.58 ? 66 LYS A C 1 ATOM 300 O O . LYS A 1 46 ? -48.011 -16.235 84.585 1.00 28.18 ? 66 LYS A O 1 ATOM 301 C CB . LYS A 1 46 ? -47.393 -13.874 86.708 1.00 29.32 ? 66 LYS A CB 1 ATOM 302 C CG . LYS A 1 46 ? -46.329 -13.761 85.626 1.00 30.38 ? 66 LYS A CG 1 ATOM 303 C CD . LYS A 1 46 ? -45.704 -12.377 85.571 1.00 31.65 ? 66 LYS A CD 1 ATOM 304 C CE . LYS A 1 46 ? -44.616 -12.335 84.503 1.00 32.00 ? 66 LYS A CE 1 ATOM 305 N NZ . LYS A 1 46 ? -43.894 -11.033 84.497 1.00 32.93 ? 66 LYS A NZ 1 ATOM 306 N N . ASN A 1 47 ? -49.851 -15.077 85.158 1.00 28.13 ? 67 ASN A N 1 ATOM 307 C CA . ASN A 1 47 ? -50.456 -15.099 83.835 1.00 27.78 ? 67 ASN A CA 1 ATOM 308 C C . ASN A 1 47 ? -50.220 -13.748 83.139 1.00 27.50 ? 67 ASN A C 1 ATOM 309 O O . ASN A 1 47 ? -50.557 -12.710 83.702 1.00 27.42 ? 67 ASN A O 1 ATOM 310 C CB . ASN A 1 47 ? -51.949 -15.383 83.958 1.00 27.69 ? 67 ASN A CB 1 ATOM 311 C CG . ASN A 1 47 ? -52.247 -16.807 84.417 1.00 27.79 ? 67 ASN A CG 1 ATOM 312 O OD1 . ASN A 1 47 ? -51.348 -17.644 84.546 1.00 27.49 ? 67 ASN A OD1 1 ATOM 313 N ND2 . ASN A 1 47 ? -53.527 -17.092 84.642 1.00 27.42 ? 67 ASN A ND2 1 ATOM 314 N N . THR A 1 48 ? -49.643 -13.768 81.932 1.00 27.04 ? 68 THR A N 1 ATOM 315 C CA A THR A 1 48 ? -49.294 -12.539 81.210 0.50 26.89 ? 68 THR A CA 1 ATOM 316 C CA B THR A 1 48 ? -49.305 -12.538 81.199 0.50 26.68 ? 68 THR A CA 1 ATOM 317 C C . THR A 1 48 ? -49.497 -12.711 79.700 1.00 26.59 ? 68 THR A C 1 ATOM 318 O O . THR A 1 48 ? -49.381 -13.821 79.176 1.00 26.82 ? 68 THR A O 1 ATOM 319 C CB A THR A 1 48 ? -47.823 -12.127 81.511 0.50 26.93 ? 68 THR A CB 1 ATOM 320 C CB B THR A 1 48 ? -47.836 -12.111 81.430 0.50 26.68 ? 68 THR A CB 1 ATOM 321 O OG1 A THR A 1 48 ? -47.632 -10.734 81.233 0.50 27.67 ? 68 THR A OG1 1 ATOM 322 O OG1 B THR A 1 48 ? -46.945 -13.107 80.903 0.50 26.51 ? 68 THR A OG1 1 ATOM 323 C CG2 A THR A 1 48 ? -46.833 -12.957 80.693 0.50 26.82 ? 68 THR A CG2 1 ATOM 324 C CG2 B THR A 1 48 ? -47.561 -11.903 82.905 0.50 26.06 ? 68 THR A CG2 1 ATOM 325 N N . VAL A 1 49 ? -49.797 -11.610 79.012 1.00 25.98 ? 69 VAL A N 1 ATOM 326 C CA . VAL A 1 49 ? -49.890 -11.610 77.562 1.00 25.17 ? 69 VAL A CA 1 ATOM 327 C C . VAL A 1 49 ? -48.493 -11.269 77.020 1.00 24.60 ? 69 VAL A C 1 ATOM 328 O O . VAL A 1 49 ? -47.992 -10.169 77.195 1.00 24.50 ? 69 VAL A O 1 ATOM 329 C CB . VAL A 1 49 ? -50.943 -10.616 77.039 1.00 25.26 ? 69 VAL A CB 1 ATOM 330 C CG1 . VAL A 1 49 ? -51.153 -10.808 75.530 1.00 24.89 ? 69 VAL A CG1 1 ATOM 331 C CG2 . VAL A 1 49 ? -52.285 -10.777 77.784 1.00 25.12 ? 69 VAL A CG2 1 ATOM 332 N N . PHE A 1 50 ? -47.854 -12.233 76.379 1.00 24.10 ? 70 PHE A N 1 ATOM 333 C CA . PHE A 1 50 ? -46.457 -12.078 75.989 1.00 23.47 ? 70 PHE A CA 1 ATOM 334 C C . PHE A 1 50 ? -46.321 -11.347 74.651 1.00 23.23 ? 70 PHE A C 1 ATOM 335 O O . PHE A 1 50 ? -45.410 -10.523 74.475 1.00 22.81 ? 70 PHE A O 1 ATOM 336 C CB . PHE A 1 50 ? -45.785 -13.436 75.907 1.00 23.13 ? 70 PHE A CB 1 ATOM 337 C CG . PHE A 1 50 ? -44.325 -13.359 75.601 1.00 23.58 ? 70 PHE A CG 1 ATOM 338 C CD1 . PHE A 1 50 ? -43.439 -12.861 76.542 1.00 23.47 ? 70 PHE A CD1 1 ATOM 339 C CD2 . PHE A 1 50 ? -43.832 -13.782 74.369 1.00 23.62 ? 70 PHE A CD2 1 ATOM 340 C CE1 . PHE A 1 50 ? -42.080 -12.787 76.265 1.00 24.88 ? 70 PHE A CE1 1 ATOM 341 C CE2 . PHE A 1 50 ? -42.468 -13.710 74.085 1.00 23.10 ? 70 PHE A CE2 1 ATOM 342 C CZ . PHE A 1 50 ? -41.595 -13.218 75.032 1.00 23.33 ? 70 PHE A CZ 1 ATOM 343 N N . LEU A 1 51 ? -47.233 -11.645 73.732 1.00 22.77 ? 71 LEU A N 1 ATOM 344 C CA . LEU A 1 51 ? -47.162 -11.133 72.367 1.00 23.08 ? 71 LEU A CA 1 ATOM 345 C C . LEU A 1 51 ? -48.558 -10.877 71.834 1.00 22.87 ? 71 LEU A C 1 ATOM 346 O O . LEU A 1 51 ? -49.468 -11.675 72.065 1.00 22.49 ? 71 LEU A O 1 ATOM 347 C CB . LEU A 1 51 ? -46.452 -12.149 71.462 1.00 22.98 ? 71 LEU A CB 1 ATOM 348 C CG . LEU A 1 51 ? -46.480 -11.937 69.946 1.00 23.77 ? 71 LEU A CG 1 ATOM 349 C CD1 . LEU A 1 51 ? -45.784 -10.633 69.573 1.00 23.92 ? 71 LEU A CD1 1 ATOM 350 C CD2 . LEU A 1 51 ? -45.821 -13.119 69.233 1.00 23.79 ? 71 LEU A CD2 1 ATOM 351 N N . ILE A 1 52 ? -48.707 -9.759 71.119 1.00 22.75 ? 72 ILE A N 1 ATOM 352 C CA . ILE A 1 52 ? -49.895 -9.477 70.315 1.00 22.66 ? 72 ILE A CA 1 ATOM 353 C C . ILE A 1 52 ? -49.428 -8.945 68.959 1.00 22.63 ? 72 ILE A C 1 ATOM 354 O O . ILE A 1 52 ? -48.638 -7.992 68.895 1.00 22.13 ? 72 ILE A O 1 ATOM 355 C CB . ILE A 1 52 ? -50.820 -8.400 70.951 1.00 22.81 ? 72 ILE A CB 1 ATOM 356 C CG1 . ILE A 1 52 ? -51.276 -8.795 72.358 1.00 22.92 ? 72 ILE A CG1 1 ATOM 357 C CG2 . ILE A 1 52 ? -52.035 -8.125 70.052 1.00 22.06 ? 72 ILE A CG2 1 ATOM 358 C CD1 . ILE A 1 52 ? -51.884 -7.599 73.139 1.00 22.93 ? 72 ILE A CD1 1 ATOM 359 N N . GLU A 1 53 ? -49.926 -9.556 67.885 1.00 22.49 ? 73 GLU A N 1 ATOM 360 C CA . GLU A 1 53 ? -49.627 -9.103 66.527 1.00 22.44 ? 73 GLU A CA 1 ATOM 361 C C . GLU A 1 53 ? -50.783 -9.476 65.610 1.00 22.58 ? 73 GLU A C 1 ATOM 362 O O . GLU A 1 53 ? -51.609 -10.307 65.963 1.00 22.36 ? 73 GLU A O 1 ATOM 363 C CB . GLU A 1 53 ? -48.307 -9.710 66.026 1.00 22.06 ? 73 GLU A CB 1 ATOM 364 C CG . GLU A 1 53 ? -48.309 -11.235 65.864 1.00 22.07 ? 73 GLU A CG 1 ATOM 365 C CD . GLU A 1 53 ? -46.944 -11.804 65.428 1.00 21.78 ? 73 GLU A CD 1 ATOM 366 O OE1 . GLU A 1 53 ? -45.928 -11.093 65.500 1.00 20.31 ? 73 GLU A OE1 1 ATOM 367 O OE2 . GLU A 1 53 ? -46.891 -12.971 65.010 1.00 21.91 ? 73 GLU A OE2 1 ATOM 368 N N . MET A 1 54 ? -50.855 -8.838 64.446 1.00 23.02 ? 74 MET A N 1 ATOM 369 C CA . MET A 1 54 ? -51.912 -9.124 63.478 1.00 23.05 ? 74 MET A CA 1 ATOM 370 C C . MET A 1 54 ? -51.787 -10.553 62.949 1.00 23.12 ? 74 MET A C 1 ATOM 371 O O . MET A 1 54 ? -50.683 -11.018 62.650 1.00 22.95 ? 74 MET A O 1 ATOM 372 C CB . MET A 1 54 ? -51.874 -8.133 62.306 1.00 23.13 ? 74 MET A CB 1 ATOM 373 C CG . MET A 1 54 ? -53.042 -8.281 61.337 1.00 23.78 ? 74 MET A CG 1 ATOM 374 S SD . MET A 1 54 ? -52.760 -9.442 59.979 1.00 24.53 ? 74 MET A SD 1 ATOM 375 C CE . MET A 1 54 ? -51.568 -8.543 58.968 1.00 26.73 ? 74 MET A CE 1 ATOM 376 N N . LEU A 1 55 ? -52.941 -11.218 62.820 1.00 22.95 ? 75 LEU A N 1 ATOM 377 C CA . LEU A 1 55 ? -53.041 -12.577 62.333 1.00 22.89 ? 75 LEU A CA 1 ATOM 378 C C . LEU A 1 55 ? -53.665 -12.539 60.944 1.00 23.31 ? 75 LEU A C 1 ATOM 379 O O . LEU A 1 55 ? -54.850 -12.237 60.786 1.00 22.78 ? 75 LEU A O 1 ATOM 380 C CB . LEU A 1 55 ? -53.902 -13.430 63.281 1.00 23.00 ? 75 LEU A CB 1 ATOM 381 C CG . LEU A 1 55 ? -54.170 -14.889 62.878 1.00 23.08 ? 75 LEU A CG 1 ATOM 382 C CD1 . LEU A 1 55 ? -52.864 -15.698 62.939 1.00 23.84 ? 75 LEU A CD1 1 ATOM 383 C CD2 . LEU A 1 55 ? -55.253 -15.535 63.760 1.00 23.14 ? 75 LEU A CD2 1 ATOM 384 N N . LEU A 1 56 ? -52.855 -12.867 59.942 1.00 23.59 ? 76 LEU A N 1 ATOM 385 C CA . LEU A 1 56 ? -53.281 -12.795 58.556 1.00 24.07 ? 76 LEU A CA 1 ATOM 386 C C . LEU A 1 56 ? -54.531 -13.643 58.307 1.00 23.70 ? 76 LEU A C 1 ATOM 387 O O . LEU A 1 56 ? -54.600 -14.775 58.768 1.00 23.68 ? 76 LEU A O 1 ATOM 388 C CB . LEU A 1 56 ? -52.139 -13.269 57.656 1.00 24.19 ? 76 LEU A CB 1 ATOM 389 C CG . LEU A 1 56 ? -52.182 -12.778 56.222 1.00 25.49 ? 76 LEU A CG 1 ATOM 390 C CD1 . LEU A 1 56 ? -52.146 -11.259 56.197 1.00 25.42 ? 76 LEU A CD1 1 ATOM 391 C CD2 . LEU A 1 56 ? -51.015 -13.384 55.428 1.00 27.51 ? 76 LEU A CD2 1 ATOM 392 N N . PRO A 1 57 ? -55.525 -13.103 57.582 1.00 23.81 ? 77 PRO A N 1 ATOM 393 C CA . PRO A 1 57 ? -56.666 -13.959 57.232 1.00 24.06 ? 77 PRO A CA 1 ATOM 394 C C . PRO A 1 57 ? -56.273 -15.037 56.231 1.00 24.14 ? 77 PRO A C 1 ATOM 395 O O . PRO A 1 57 ? -55.173 -15.001 55.680 1.00 24.39 ? 77 PRO A O 1 ATOM 396 C CB . PRO A 1 57 ? -57.663 -12.996 56.577 1.00 23.88 ? 77 PRO A CB 1 ATOM 397 C CG . PRO A 1 57 ? -57.133 -11.626 56.799 1.00 23.83 ? 77 PRO A CG 1 ATOM 398 C CD . PRO A 1 57 ? -55.657 -11.761 56.999 1.00 23.80 ? 77 PRO A CD 1 ATOM 399 N N . LYS A 1 58 ? -57.180 -15.970 55.984 1.00 24.30 ? 78 LYS A N 1 ATOM 400 C CA . LYS A 1 58 ? -56.952 -17.015 55.003 1.00 24.87 ? 78 LYS A CA 1 ATOM 401 C C . LYS A 1 58 ? -56.774 -16.432 53.595 1.00 24.89 ? 78 LYS A C 1 ATOM 402 O O . LYS A 1 58 ? -57.480 -15.486 53.195 1.00 25.14 ? 78 LYS A O 1 ATOM 403 C CB . LYS A 1 58 ? -58.107 -18.023 55.021 1.00 25.28 ? 78 LYS A CB 1 ATOM 404 C CG . LYS A 1 58 ? -58.217 -18.799 56.350 1.00 25.56 ? 78 LYS A CG 1 ATOM 405 C CD . LYS A 1 58 ? -59.493 -19.621 56.404 1.00 26.72 ? 78 LYS A CD 1 ATOM 406 C CE . LYS A 1 58 ? -59.474 -20.603 57.568 1.00 27.42 ? 78 LYS A CE 1 ATOM 407 N N . LYS A 1 59 ? -55.833 -17.012 52.853 1.00 24.45 ? 79 LYS A N 1 ATOM 408 C CA . LYS A 1 59 ? -55.524 -16.584 51.482 1.00 24.46 ? 79 LYS A CA 1 ATOM 409 C C . LYS A 1 59 ? -56.747 -16.672 50.579 1.00 24.70 ? 79 LYS A C 1 ATOM 410 O O . LYS A 1 59 ? -56.978 -15.790 49.760 1.00 24.68 ? 79 LYS A O 1 ATOM 411 C CB . LYS A 1 59 ? -54.371 -17.432 50.915 1.00 24.14 ? 79 LYS A CB 1 ATOM 412 C CG . LYS A 1 59 ? -53.899 -17.081 49.491 1.00 23.25 ? 79 LYS A CG 1 ATOM 413 C CD . LYS A 1 59 ? -52.582 -17.838 49.180 1.00 22.17 ? 79 LYS A CD 1 ATOM 414 C CE . LYS A 1 59 ? -52.099 -17.640 47.742 1.00 22.24 ? 79 LYS A CE 1 ATOM 415 N NZ . LYS A 1 59 ? -50.871 -18.445 47.409 1.00 20.43 ? 79 LYS A NZ 1 ATOM 416 N N . TYR A 1 60 ? -57.524 -17.736 50.731 1.00 25.29 ? 80 TYR A N 1 ATOM 417 C CA . TYR A 1 60 ? -58.762 -17.912 49.965 1.00 26.19 ? 80 TYR A CA 1 ATOM 418 C C . TYR A 1 60 ? -59.641 -16.663 50.071 1.00 25.87 ? 80 TYR A C 1 ATOM 419 O O . TYR A 1 60 ? -60.128 -16.142 49.075 1.00 26.16 ? 80 TYR A O 1 ATOM 420 C CB . TYR A 1 60 ? -59.533 -19.140 50.478 1.00 26.67 ? 80 TYR A CB 1 ATOM 421 C CG . TYR A 1 60 ? -60.891 -19.317 49.837 1.00 28.43 ? 80 TYR A CG 1 ATOM 422 C CD1 . TYR A 1 60 ? -61.019 -19.925 48.595 1.00 30.50 ? 80 TYR A CD1 1 ATOM 423 C CD2 . TYR A 1 60 ? -62.045 -18.858 50.471 1.00 30.98 ? 80 TYR A CD2 1 ATOM 424 C CE1 . TYR A 1 60 ? -62.264 -20.079 47.996 1.00 31.73 ? 80 TYR A CE1 1 ATOM 425 C CE2 . TYR A 1 60 ? -63.291 -19.004 49.886 1.00 32.32 ? 80 TYR A CE2 1 ATOM 426 C CZ . TYR A 1 60 ? -63.395 -19.619 48.649 1.00 33.39 ? 80 TYR A CZ 1 ATOM 427 O OH . TYR A 1 60 ? -64.635 -19.764 48.068 1.00 37.10 ? 80 TYR A OH 1 ATOM 428 N N . HIS A 1 61 ? -59.805 -16.176 51.290 1.00 26.06 ? 81 HIS A N 1 ATOM 429 C CA . HIS A 1 61 ? -60.665 -15.029 51.560 1.00 26.06 ? 81 HIS A CA 1 ATOM 430 C C . HIS A 1 61 ? -60.034 -13.710 51.115 1.00 25.51 ? 81 HIS A C 1 ATOM 431 O O . HIS A 1 61 ? -60.719 -12.848 50.555 1.00 25.25 ? 81 HIS A O 1 ATOM 432 C CB . HIS A 1 61 ? -60.991 -14.982 53.045 1.00 26.40 ? 81 HIS A CB 1 ATOM 433 C CG . HIS A 1 61 ? -61.870 -16.101 53.497 1.00 28.36 ? 81 HIS A CG 1 ATOM 434 N ND1 . HIS A 1 61 ? -63.050 -16.419 52.858 1.00 30.80 ? 81 HIS A ND1 1 ATOM 435 C CD2 . HIS A 1 61 ? -61.751 -16.971 54.528 1.00 30.43 ? 81 HIS A CD2 1 ATOM 436 C CE1 . HIS A 1 61 ? -63.617 -17.441 53.477 1.00 30.93 ? 81 HIS A CE1 1 ATOM 437 N NE2 . HIS A 1 61 ? -62.850 -17.793 54.492 1.00 30.13 ? 81 HIS A NE2 1 ATOM 438 N N . VAL A 1 62 ? -58.735 -13.558 51.375 1.00 24.72 ? 82 VAL A N 1 ATOM 439 C CA . VAL A 1 62 ? -57.994 -12.377 50.950 1.00 24.17 ? 82 VAL A CA 1 ATOM 440 C C . VAL A 1 62 ? -58.068 -12.222 49.430 1.00 24.28 ? 82 VAL A C 1 ATOM 441 O O . VAL A 1 62 ? -58.362 -11.141 48.932 1.00 23.77 ? 82 VAL A O 1 ATOM 442 C CB . VAL A 1 62 ? -56.502 -12.437 51.384 1.00 23.95 ? 82 VAL A CB 1 ATOM 443 C CG1 . VAL A 1 62 ? -55.732 -11.250 50.829 1.00 23.37 ? 82 VAL A CG1 1 ATOM 444 C CG2 . VAL A 1 62 ? -56.375 -12.491 52.901 1.00 22.19 ? 82 VAL A CG2 1 ATOM 445 N N . LEU A 1 63 ? -57.811 -13.301 48.697 1.00 24.55 ? 83 LEU A N 1 ATOM 446 C CA . LEU A 1 63 ? -57.823 -13.235 47.236 1.00 25.19 ? 83 LEU A CA 1 ATOM 447 C C . LEU A 1 63 ? -59.221 -12.914 46.686 1.00 25.89 ? 83 LEU A C 1 ATOM 448 O O . LEU A 1 63 ? -59.342 -12.179 45.705 1.00 25.88 ? 83 LEU A O 1 ATOM 449 C CB . LEU A 1 63 ? -57.275 -14.525 46.599 1.00 25.08 ? 83 LEU A CB 1 ATOM 450 C CG . LEU A 1 63 ? -55.760 -14.791 46.708 1.00 24.93 ? 83 LEU A CG 1 ATOM 451 C CD1 . LEU A 1 63 ? -55.370 -15.969 45.828 1.00 23.78 ? 83 LEU A CD1 1 ATOM 452 C CD2 . LEU A 1 63 ? -54.930 -13.573 46.339 1.00 24.61 ? 83 LEU A CD2 1 ATOM 453 N N . ARG A 1 64 ? -60.269 -13.452 47.304 1.00 26.68 ? 84 ARG A N 1 ATOM 454 C CA . ARG A 1 64 ? -61.643 -13.101 46.890 1.00 27.89 ? 84 ARG A CA 1 ATOM 455 C C . ARG A 1 64 ? -61.941 -11.632 47.155 1.00 28.00 ? 84 ARG A C 1 ATOM 456 O O . ARG A 1 64 ? -62.660 -10.990 46.383 1.00 28.13 ? 84 ARG A O 1 ATOM 457 C CB . ARG A 1 64 ? -62.681 -13.998 47.566 1.00 28.06 ? 84 ARG A CB 1 ATOM 458 C CG . ARG A 1 64 ? -62.709 -15.379 46.942 1.00 30.50 ? 84 ARG A CG 1 ATOM 459 C CD . ARG A 1 64 ? -63.421 -16.393 47.804 1.00 34.50 ? 84 ARG A CD 1 ATOM 460 N NE . ARG A 1 64 ? -64.750 -15.939 48.206 1.00 37.90 ? 84 ARG A NE 1 ATOM 461 C CZ . ARG A 1 64 ? -65.809 -15.868 47.401 1.00 39.80 ? 84 ARG A CZ 1 ATOM 462 N NH1 . ARG A 1 64 ? -65.721 -16.216 46.119 1.00 40.61 ? 84 ARG A NH1 1 ATOM 463 N NH2 . ARG A 1 64 ? -66.969 -15.433 47.887 1.00 41.74 ? 84 ARG A NH2 1 ATOM 464 N N . PHE A 1 65 ? -61.371 -11.106 48.236 1.00 28.14 ? 85 PHE A N 1 ATOM 465 C CA . PHE A 1 65 ? -61.469 -9.684 48.548 1.00 28.56 ? 85 PHE A CA 1 ATOM 466 C C . PHE A 1 65 ? -60.709 -8.877 47.499 1.00 28.46 ? 85 PHE A C 1 ATOM 467 O O . PHE A 1 65 ? -61.260 -7.958 46.898 1.00 28.90 ? 85 PHE A O 1 ATOM 468 C CB . PHE A 1 65 ? -60.924 -9.417 49.953 1.00 28.58 ? 85 PHE A CB 1 ATOM 469 C CG . PHE A 1 65 ? -60.693 -7.963 50.266 1.00 29.68 ? 85 PHE A CG 1 ATOM 470 C CD1 . PHE A 1 65 ? -61.746 -7.056 50.257 1.00 30.32 ? 85 PHE A CD1 1 ATOM 471 C CD2 . PHE A 1 65 ? -59.422 -7.505 50.590 1.00 30.16 ? 85 PHE A CD2 1 ATOM 472 C CE1 . PHE A 1 65 ? -61.535 -5.723 50.559 1.00 30.45 ? 85 PHE A CE1 1 ATOM 473 C CE2 . PHE A 1 65 ? -59.204 -6.174 50.890 1.00 30.52 ? 85 PHE A CE2 1 ATOM 474 C CZ . PHE A 1 65 ? -60.265 -5.279 50.882 1.00 30.46 ? 85 PHE A CZ 1 ATOM 475 N N . LEU A 1 66 ? -59.459 -9.255 47.262 1.00 27.91 ? 86 LEU A N 1 ATOM 476 C CA . LEU A 1 66 ? -58.585 -8.534 46.345 1.00 27.68 ? 86 LEU A CA 1 ATOM 477 C C . LEU A 1 66 ? -58.985 -8.648 44.880 1.00 27.51 ? 86 LEU A C 1 ATOM 478 O O . LEU A 1 66 ? -58.937 -7.665 44.159 1.00 27.49 ? 86 LEU A O 1 ATOM 479 C CB . LEU A 1 66 ? -57.134 -9.022 46.485 1.00 27.59 ? 86 LEU A CB 1 ATOM 480 C CG . LEU A 1 66 ? -56.465 -8.849 47.849 1.00 27.08 ? 86 LEU A CG 1 ATOM 481 C CD1 . LEU A 1 66 ? -55.061 -9.397 47.784 1.00 26.05 ? 86 LEU A CD1 1 ATOM 482 C CD2 . LEU A 1 66 ? -56.469 -7.382 48.284 1.00 25.71 ? 86 LEU A CD2 1 ATOM 483 N N . ASP A 1 67 ? -59.350 -9.842 44.437 1.00 27.76 ? 87 ASP A N 1 ATOM 484 C CA . ASP A 1 67 ? -59.501 -10.108 43.009 1.00 28.01 ? 87 ASP A CA 1 ATOM 485 C C . ASP A 1 67 ? -60.955 -10.221 42.537 1.00 28.67 ? 87 ASP A C 1 ATOM 486 O O . ASP A 1 67 ? -61.203 -10.151 41.338 1.00 28.11 ? 87 ASP A O 1 ATOM 487 C CB . ASP A 1 67 ? -58.769 -11.397 42.620 1.00 27.99 ? 87 ASP A CB 1 ATOM 488 C CG . ASP A 1 67 ? -57.272 -11.379 42.962 1.00 27.89 ? 87 ASP A CG 1 ATOM 489 O OD1 . ASP A 1 67 ? -56.705 -10.306 43.264 1.00 26.20 ? 87 ASP A OD1 1 ATOM 490 O OD2 . ASP A 1 67 ? -56.660 -12.468 42.912 1.00 27.06 ? 87 ASP A OD2 1 ATOM 491 N N . LYS A 1 68 ? -61.906 -10.426 43.448 1.00 29.65 ? 88 LYS A N 1 ATOM 492 C CA . LYS A 1 68 ? -63.291 -10.740 43.034 1.00 30.78 ? 88 LYS A CA 1 ATOM 493 C C . LYS A 1 68 ? -64.341 -9.839 43.662 1.00 31.23 ? 88 LYS A C 1 ATOM 494 O O . LYS A 1 68 ? -65.527 -10.158 43.608 1.00 31.61 ? 88 LYS A O 1 ATOM 495 C CB . LYS A 1 68 ? -63.656 -12.192 43.369 1.00 31.05 ? 88 LYS A CB 1 ATOM 496 C CG . LYS A 1 68 ? -62.605 -13.222 43.049 1.00 32.73 ? 88 LYS A CG 1 ATOM 497 C CD . LYS A 1 68 ? -62.499 -13.481 41.564 1.00 35.26 ? 88 LYS A CD 1 ATOM 498 C CE . LYS A 1 68 ? -61.607 -14.691 41.287 1.00 37.11 ? 88 LYS A CE 1 ATOM 499 N NZ . LYS A 1 68 ? -62.100 -15.952 41.960 1.00 38.81 ? 88 LYS A NZ 1 ATOM 500 N N . GLY A 1 69 ? -63.918 -8.736 44.271 1.00 31.57 ? 89 GLY A N 1 ATOM 501 C CA . GLY A 1 69 ? -64.843 -7.771 44.839 1.00 31.85 ? 89 GLY A CA 1 ATOM 502 C C . GLY A 1 69 ? -65.603 -8.208 46.081 1.00 32.16 ? 89 GLY A C 1 ATOM 503 O O . GLY A 1 69 ? -66.512 -7.507 46.512 1.00 32.53 ? 89 GLY A O 1 ATOM 504 N N . GLU A 1 70 ? -65.241 -9.341 46.678 1.00 32.39 ? 90 GLU A N 1 ATOM 505 C CA . GLU A 1 70 ? -65.971 -9.844 47.852 1.00 32.45 ? 90 GLU A CA 1 ATOM 506 C C . GLU A 1 70 ? -65.582 -9.064 49.106 1.00 32.23 ? 90 GLU A C 1 ATOM 507 O O . GLU A 1 70 ? -64.720 -8.189 49.054 1.00 32.46 ? 90 GLU A O 1 ATOM 508 C CB . GLU A 1 70 ? -65.745 -11.353 48.033 1.00 32.49 ? 90 GLU A CB 1 ATOM 509 C CG . GLU A 1 70 ? -66.242 -12.199 46.856 1.00 33.44 ? 90 GLU A CG 1 ATOM 510 C CD . GLU A 1 70 ? -67.765 -12.215 46.722 1.00 33.68 ? 90 GLU A CD 1 ATOM 511 N N . ARG A 1 71 ? -66.224 -9.374 50.230 1.00 32.16 ? 91 ARG A N 1 ATOM 512 C CA . ARG A 1 71 ? -66.054 -8.598 51.458 1.00 31.93 ? 91 ARG A CA 1 ATOM 513 C C . ARG A 1 71 ? -64.640 -8.672 52.040 1.00 32.14 ? 91 ARG A C 1 ATOM 514 O O . ARG A 1 71 ? -63.928 -9.663 51.869 1.00 32.03 ? 91 ARG A O 1 ATOM 515 C CB . ARG A 1 71 ? -67.054 -9.064 52.521 1.00 31.78 ? 91 ARG A CB 1 ATOM 516 N N . HIS A 1 72 ? -64.258 -7.606 52.733 1.00 32.34 ? 92 HIS A N 1 ATOM 517 C CA . HIS A 1 72 ? -63.040 -7.561 53.534 1.00 32.63 ? 92 HIS A CA 1 ATOM 518 C C . HIS A 1 72 ? -63.068 -8.728 54.532 1.00 32.21 ? 92 HIS A C 1 ATOM 519 O O . HIS A 1 72 ? -64.085 -8.932 55.206 1.00 32.32 ? 92 HIS A O 1 ATOM 520 C CB . HIS A 1 72 ? -62.983 -6.226 54.292 1.00 32.98 ? 92 HIS A CB 1 ATOM 521 C CG . HIS A 1 72 ? -61.596 -5.747 54.597 1.00 34.82 ? 92 HIS A CG 1 ATOM 522 N ND1 . HIS A 1 72 ? -60.764 -6.378 55.499 1.00 36.99 ? 92 HIS A ND1 1 ATOM 523 C CD2 . HIS A 1 72 ? -60.909 -4.671 54.144 1.00 36.49 ? 92 HIS A CD2 1 ATOM 524 C CE1 . HIS A 1 72 ? -59.620 -5.719 55.575 1.00 37.33 ? 92 HIS A CE1 1 ATOM 525 N NE2 . HIS A 1 72 ? -59.681 -4.680 54.763 1.00 37.10 ? 92 HIS A NE2 1 ATOM 526 N N . PRO A 1 73 ? -61.969 -9.508 54.623 1.00 31.32 ? 93 PRO A N 1 ATOM 527 C CA . PRO A 1 73 ? -61.930 -10.550 55.644 1.00 30.61 ? 93 PRO A CA 1 ATOM 528 C C . PRO A 1 73 ? -61.911 -9.961 57.044 1.00 29.74 ? 93 PRO A C 1 ATOM 529 O O . PRO A 1 73 ? -61.440 -8.844 57.233 1.00 29.34 ? 93 PRO A O 1 ATOM 530 C CB . PRO A 1 73 ? -60.606 -11.286 55.355 1.00 30.68 ? 93 PRO A CB 1 ATOM 531 C CG . PRO A 1 73 ? -60.276 -10.951 53.969 1.00 31.06 ? 93 PRO A CG 1 ATOM 532 C CD . PRO A 1 73 ? -60.789 -9.572 53.747 1.00 31.37 ? 93 PRO A CD 1 ATOM 533 N N . VAL A 1 74 ? -62.420 -10.720 58.008 1.00 29.23 ? 94 VAL A N 1 ATOM 534 C CA . VAL A 1 74 ? -62.401 -10.320 59.411 1.00 28.44 ? 94 VAL A CA 1 ATOM 535 C C . VAL A 1 74 ? -60.950 -10.125 59.854 1.00 27.99 ? 94 VAL A C 1 ATOM 536 O O . VAL A 1 74 ? -60.073 -10.923 59.514 1.00 27.77 ? 94 VAL A O 1 ATOM 537 C CB . VAL A 1 74 ? -63.089 -11.373 60.308 1.00 28.73 ? 94 VAL A CB 1 ATOM 538 C CG1 . VAL A 1 74 ? -62.863 -11.050 61.780 1.00 29.36 ? 94 VAL A CG1 1 ATOM 539 C CG2 . VAL A 1 74 ? -64.600 -11.450 59.990 1.00 28.19 ? 94 VAL A CG2 1 ATOM 540 N N . ARG A 1 75 ? -60.710 -9.040 60.582 1.00 26.93 ? 95 ARG A N 1 ATOM 541 C CA . ARG A 1 75 ? -59.388 -8.707 61.073 1.00 26.20 ? 95 ARG A CA 1 ATOM 542 C C . ARG A 1 75 ? -59.239 -9.230 62.498 1.00 25.63 ? 95 ARG A C 1 ATOM 543 O O . ARG A 1 75 ? -60.130 -9.026 63.342 1.00 25.13 ? 95 ARG A O 1 ATOM 544 C CB . ARG A 1 75 ? -59.188 -7.189 61.018 1.00 26.44 ? 95 ARG A CB 1 ATOM 545 C CG . ARG A 1 75 ? -57.778 -6.710 61.314 1.00 25.79 ? 95 ARG A CG 1 ATOM 546 C CD . ARG A 1 75 ? -57.596 -5.319 60.764 1.00 24.84 ? 95 ARG A CD 1 ATOM 547 N NE . ARG A 1 75 ? -56.441 -4.612 61.310 1.00 23.38 ? 95 ARG A NE 1 ATOM 548 C CZ . ARG A 1 75 ? -55.207 -4.648 60.811 1.00 23.14 ? 95 ARG A CZ 1 ATOM 549 N NH1 . ARG A 1 75 ? -54.906 -5.397 59.751 1.00 22.74 ? 95 ARG A NH1 1 ATOM 550 N NH2 . ARG A 1 75 ? -54.255 -3.932 61.391 1.00 23.98 ? 95 ARG A NH2 1 ATOM 551 N N . GLU A 1 76 ? -58.122 -9.921 62.747 1.00 24.57 ? 96 GLU A N 1 ATOM 552 C CA . GLU A 1 76 ? -57.840 -10.539 64.042 1.00 23.86 ? 96 GLU A CA 1 ATOM 553 C C . GLU A 1 76 ? -56.412 -10.298 64.494 1.00 23.12 ? 96 GLU A C 1 ATOM 554 O O . GLU A 1 76 ? -55.543 -9.957 63.692 1.00 22.79 ? 96 GLU A O 1 ATOM 555 C CB . GLU A 1 76 ? -58.035 -12.047 63.958 1.00 23.93 ? 96 GLU A CB 1 ATOM 556 C CG . GLU A 1 76 ? -59.387 -12.497 63.470 1.00 24.27 ? 96 GLU A CG 1 ATOM 557 C CD . GLU A 1 76 ? -59.510 -14.010 63.502 1.00 25.36 ? 96 GLU A CD 1 ATOM 558 O OE1 . GLU A 1 76 ? -58.669 -14.692 62.878 1.00 24.85 ? 96 GLU A OE1 1 ATOM 559 O OE2 . GLU A 1 76 ? -60.432 -14.519 64.165 1.00 25.95 ? 96 GLU A OE2 1 ATOM 560 N N . ALA A 1 77 ? -56.171 -10.524 65.781 1.00 22.43 ? 97 ALA A N 1 ATOM 561 C CA . ALA A 1 77 ? -54.826 -10.459 66.349 1.00 22.17 ? 97 ALA A CA 1 ATOM 562 C C . ALA A 1 77 ? -54.489 -11.796 66.964 1.00 22.17 ? 97 ALA A C 1 ATOM 563 O O . ALA A 1 77 ? -55.338 -12.426 67.594 1.00 22.36 ? 97 ALA A O 1 ATOM 564 C CB . ALA A 1 77 ? -54.724 -9.374 67.418 1.00 21.43 ? 97 ALA A CB 1 ATOM 565 N N . ARG A 1 78 ? -53.243 -12.217 66.783 1.00 21.76 ? 98 ARG A N 1 ATOM 566 C CA . ARG A 1 78 ? -52.687 -13.325 67.537 1.00 21.74 ? 98 ARG A CA 1 ATOM 567 C C . ARG A 1 78 ? -52.313 -12.788 68.916 1.00 21.94 ? 98 ARG A C 1 ATOM 568 O O . ARG A 1 78 ? -51.685 -11.738 69.018 1.00 21.83 ? 98 ARG A O 1 ATOM 569 C CB . ARG A 1 78 ? -51.455 -13.864 66.807 1.00 21.63 ? 98 ARG A CB 1 ATOM 570 C CG . ARG A 1 78 ? -50.614 -14.860 67.575 1.00 22.12 ? 98 ARG A CG 1 ATOM 571 C CD . ARG A 1 78 ? -49.268 -15.042 66.915 1.00 21.25 ? 98 ARG A CD 1 ATOM 572 N NE . ARG A 1 78 ? -48.476 -16.073 67.579 1.00 22.71 ? 98 ARG A NE 1 ATOM 573 C CZ . ARG A 1 78 ? -47.210 -16.358 67.276 1.00 24.31 ? 98 ARG A CZ 1 ATOM 574 N NH1 . ARG A 1 78 ? -46.569 -15.660 66.340 1.00 23.71 ? 98 ARG A NH1 1 ATOM 575 N NH2 . ARG A 1 78 ? -46.569 -17.327 67.929 1.00 24.35 ? 98 ARG A NH2 1 ATOM 576 N N . ALA A 1 79 ? -52.709 -13.505 69.964 1.00 21.98 ? 99 ALA A N 1 ATOM 577 C CA . ALA A 1 79 ? -52.346 -13.171 71.338 1.00 22.52 ? 99 ALA A CA 1 ATOM 578 C C . ALA A 1 79 ? -51.727 -14.400 71.981 1.00 22.43 ? 99 ALA A C 1 ATOM 579 O O . ALA A 1 79 ? -52.352 -15.447 72.026 1.00 22.93 ? 99 ALA A O 1 ATOM 580 C CB . ALA A 1 79 ? -53.577 -12.750 72.124 1.00 22.78 ? 99 ALA A CB 1 ATOM 581 N N . VAL A 1 80 ? -50.498 -14.276 72.461 1.00 22.73 ? 100 VAL A N 1 ATOM 582 C CA . VAL A 1 80 ? -49.817 -15.381 73.118 1.00 22.63 ? 100 VAL A CA 1 ATOM 583 C C . VAL A 1 80 ? -49.860 -15.125 74.613 1.00 22.99 ? 100 VAL A C 1 ATOM 584 O O . VAL A 1 80 ? -49.335 -14.116 75.091 1.00 22.77 ? 100 VAL A O 1 ATOM 585 C CB . VAL A 1 80 ? -48.357 -15.494 72.669 1.00 22.65 ? 100 VAL A CB 1 ATOM 586 C CG1 . VAL A 1 80 ? -47.628 -16.568 73.473 1.00 22.25 ? 100 VAL A CG1 1 ATOM 587 C CG2 . VAL A 1 80 ? -48.278 -15.786 71.162 1.00 22.66 ? 100 VAL A CG2 1 ATOM 588 N N . ILE A 1 81 ? -50.487 -16.035 75.347 1.00 23.52 ? 101 ILE A N 1 ATOM 589 C CA . ILE A 1 81 ? -50.607 -15.899 76.800 1.00 24.01 ? 101 ILE A CA 1 ATOM 590 C C . ILE A 1 81 ? -49.772 -16.938 77.533 1.00 24.09 ? 101 ILE A C 1 ATOM 591 O O . ILE A 1 81 ? -49.941 -18.142 77.323 1.00 23.88 ? 101 ILE A O 1 ATOM 592 C CB . ILE A 1 81 ? -52.071 -16.025 77.253 1.00 24.03 ? 101 ILE A CB 1 ATOM 593 C CG1 . ILE A 1 81 ? -52.914 -14.932 76.583 1.00 24.67 ? 101 ILE A CG1 1 ATOM 594 C CG2 . ILE A 1 81 ? -52.149 -15.923 78.772 1.00 24.42 ? 101 ILE A CG2 1 ATOM 595 C CD1 . ILE A 1 81 ? -54.387 -14.975 76.930 1.00 25.78 ? 101 ILE A CD1 1 ATOM 596 N N . PHE A 1 82 ? -48.878 -16.453 78.391 1.00 24.30 ? 102 PHE A N 1 ATOM 597 C CA . PHE A 1 82 ? -48.120 -17.288 79.309 1.00 24.60 ? 102 PHE A CA 1 ATOM 598 C C . PHE A 1 82 ? -48.986 -17.579 80.533 1.00 25.14 ? 102 PHE A C 1 ATOM 599 O O . PHE A 1 82 ? -49.257 -16.680 81.313 1.00 25.70 ? 102 PHE A O 1 ATOM 600 C CB . PHE A 1 82 ? -46.870 -16.540 79.792 1.00 24.22 ? 102 PHE A CB 1 ATOM 601 C CG . PHE A 1 82 ? -45.731 -16.504 78.810 1.00 24.11 ? 102 PHE A CG 1 ATOM 602 C CD1 . PHE A 1 82 ? -45.898 -16.830 77.467 1.00 23.62 ? 102 PHE A CD1 1 ATOM 603 C CD2 . PHE A 1 82 ? -44.473 -16.101 79.241 1.00 24.61 ? 102 PHE A CD2 1 ATOM 604 C CE1 . PHE A 1 82 ? -44.832 -16.785 76.589 1.00 23.61 ? 102 PHE A CE1 1 ATOM 605 C CE2 . PHE A 1 82 ? -43.403 -16.048 78.361 1.00 24.23 ? 102 PHE A CE2 1 ATOM 606 C CZ . PHE A 1 82 ? -43.588 -16.392 77.028 1.00 23.97 ? 102 PHE A CZ 1 ATOM 607 N N . PHE A 1 83 ? -49.390 -18.827 80.721 1.00 25.79 ? 103 PHE A N 1 ATOM 608 C CA . PHE A 1 83 ? -50.173 -19.217 81.892 1.00 26.17 ? 103 PHE A CA 1 ATOM 609 C C . PHE A 1 83 ? -49.264 -19.823 82.954 1.00 26.73 ? 103 PHE A C 1 ATOM 610 O O . PHE A 1 83 ? -49.201 -21.035 83.110 1.00 26.44 ? 103 PHE A O 1 ATOM 611 C CB . PHE A 1 83 ? -51.280 -20.202 81.502 1.00 26.07 ? 103 PHE A CB 1 ATOM 612 C CG . PHE A 1 83 ? -52.469 -19.560 80.846 1.00 26.35 ? 103 PHE A CG 1 ATOM 613 C CD1 . PHE A 1 83 ? -53.321 -18.738 81.577 1.00 25.88 ? 103 PHE A CD1 1 ATOM 614 C CD2 . PHE A 1 83 ? -52.771 -19.809 79.511 1.00 27.04 ? 103 PHE A CD2 1 ATOM 615 C CE1 . PHE A 1 83 ? -54.437 -18.165 80.987 1.00 25.66 ? 103 PHE A CE1 1 ATOM 616 C CE2 . PHE A 1 83 ? -53.888 -19.231 78.911 1.00 26.68 ? 103 PHE A CE2 1 ATOM 617 C CZ . PHE A 1 83 ? -54.720 -18.404 79.648 1.00 26.23 ? 103 PHE A CZ 1 ATOM 618 N N . GLY A 1 84 ? -48.557 -18.961 83.677 1.00 27.87 ? 104 GLY A N 1 ATOM 619 C CA . GLY A 1 84 ? -47.675 -19.381 84.761 1.00 28.74 ? 104 GLY A CA 1 ATOM 620 C C . GLY A 1 84 ? -48.367 -19.593 86.107 1.00 29.56 ? 104 GLY A C 1 ATOM 621 O O . GLY A 1 84 ? -47.820 -20.286 86.974 1.00 30.15 ? 104 GLY A O 1 ATOM 622 N N . ASP A 1 85 ? -49.569 -19.031 86.274 1.00 30.25 ? 105 ASP A N 1 ATOM 623 C CA . ASP A 1 85 ? -50.236 -18.949 87.587 1.00 31.10 ? 105 ASP A CA 1 ATOM 624 C C . ASP A 1 85 ? -51.226 -20.099 87.767 1.00 31.43 ? 105 ASP A C 1 ATOM 625 O O . ASP A 1 85 ? -52.426 -19.898 87.914 1.00 31.79 ? 105 ASP A O 1 ATOM 626 C CB . ASP A 1 85 ? -50.940 -17.591 87.726 1.00 31.29 ? 105 ASP A CB 1 ATOM 627 C CG . ASP A 1 85 ? -51.414 -17.301 89.142 1.00 32.42 ? 105 ASP A CG 1 ATOM 628 O OD1 . ASP A 1 85 ? -50.942 -17.957 90.095 1.00 33.06 ? 105 ASP A OD1 1 ATOM 629 O OD2 . ASP A 1 85 ? -52.268 -16.399 89.297 1.00 33.81 ? 105 ASP A OD2 1 ATOM 630 N N . GLN A 1 86 ? -50.698 -21.313 87.737 1.00 31.98 ? 106 GLN A N 1 ATOM 631 C CA . GLN A 1 86 ? -51.504 -22.525 87.819 1.00 32.36 ? 106 GLN A CA 1 ATOM 632 C C . GLN A 1 86 ? -50.555 -23.681 88.058 1.00 32.95 ? 106 GLN A C 1 ATOM 633 O O . GLN A 1 86 ? -49.336 -23.531 87.907 1.00 33.01 ? 106 GLN A O 1 ATOM 634 C CB . GLN A 1 86 ? -52.323 -22.753 86.544 1.00 32.44 ? 106 GLN A CB 1 ATOM 635 C CG . GLN A 1 86 ? -51.495 -22.885 85.241 1.00 32.27 ? 106 GLN A CG 1 ATOM 636 C CD . GLN A 1 86 ? -52.347 -22.761 83.980 1.00 31.72 ? 106 GLN A CD 1 ATOM 637 O OE1 . GLN A 1 86 ? -53.236 -21.910 83.898 1.00 32.83 ? 106 GLN A OE1 1 ATOM 638 N NE2 . GLN A 1 86 ? -52.066 -23.597 82.987 1.00 30.44 ? 106 GLN A NE2 1 ATOM 639 N N . GLU A 1 87 ? -51.110 -24.824 88.446 1.00 33.38 ? 107 GLU A N 1 ATOM 640 C CA . GLU A 1 87 ? -50.306 -25.999 88.806 1.00 33.53 ? 107 GLU A CA 1 ATOM 641 C C . GLU A 1 87 ? -49.485 -26.544 87.635 1.00 32.89 ? 107 GLU A C 1 ATOM 642 O O . GLU A 1 87 ? -48.337 -26.943 87.809 1.00 32.77 ? 107 GLU A O 1 ATOM 643 C CB . GLU A 1 87 ? -51.224 -27.101 89.323 1.00 34.09 ? 107 GLU A CB 1 ATOM 644 C CG . GLU A 1 87 ? -50.501 -28.277 89.938 1.00 36.18 ? 107 GLU A CG 1 ATOM 645 C CD . GLU A 1 87 ? -51.422 -29.454 90.179 1.00 38.62 ? 107 GLU A CD 1 ATOM 646 O OE1 . GLU A 1 87 ? -52.618 -29.390 89.801 1.00 39.96 ? 107 GLU A OE1 1 ATOM 647 O OE2 . GLU A 1 87 ? -50.935 -30.450 90.743 1.00 41.20 ? 107 GLU A OE2 1 ATOM 648 N N . HIS A 1 88 ? -50.091 -26.583 86.451 1.00 32.15 ? 108 HIS A N 1 ATOM 649 C CA . HIS A 1 88 ? -49.403 -27.038 85.249 1.00 31.51 ? 108 HIS A CA 1 ATOM 650 C C . HIS A 1 88 ? -49.277 -25.869 84.273 1.00 30.55 ? 108 HIS A C 1 ATOM 651 O O . HIS A 1 88 ? -50.138 -25.676 83.400 1.00 30.37 ? 108 HIS A O 1 ATOM 652 C CB . HIS A 1 88 ? -50.157 -28.204 84.617 1.00 31.60 ? 108 HIS A CB 1 ATOM 653 C CG . HIS A 1 88 ? -50.334 -29.366 85.542 1.00 32.88 ? 108 HIS A CG 1 ATOM 654 N ND1 . HIS A 1 88 ? -49.285 -30.169 85.933 1.00 33.42 ? 108 HIS A ND1 1 ATOM 655 C CD2 . HIS A 1 88 ? -51.435 -29.854 86.160 1.00 33.28 ? 108 HIS A CD2 1 ATOM 656 C CE1 . HIS A 1 88 ? -49.732 -31.102 86.754 1.00 34.61 ? 108 HIS A CE1 1 ATOM 657 N NE2 . HIS A 1 88 ? -51.034 -30.937 86.903 1.00 34.97 ? 108 HIS A NE2 1 ATOM 658 N N . PRO A 1 89 ? -48.206 -25.077 84.425 1.00 29.55 ? 109 PRO A N 1 ATOM 659 C CA . PRO A 1 89 ? -48.021 -23.914 83.563 1.00 28.98 ? 109 PRO A CA 1 ATOM 660 C C . PRO A 1 89 ? -48.011 -24.293 82.081 1.00 28.17 ? 109 PRO A C 1 ATOM 661 O O . PRO A 1 89 ? -47.615 -25.390 81.733 1.00 28.04 ? 109 PRO A O 1 ATOM 662 C CB . PRO A 1 89 ? -46.652 -23.373 83.993 1.00 28.93 ? 109 PRO A CB 1 ATOM 663 C CG . PRO A 1 89 ? -46.443 -23.888 85.356 1.00 29.37 ? 109 PRO A CG 1 ATOM 664 C CD . PRO A 1 89 ? -47.095 -25.223 85.383 1.00 29.44 ? 109 PRO A CD 1 ATOM 665 N N . ASN A 1 90 ? -48.493 -23.404 81.224 1.00 27.68 ? 110 ASN A N 1 ATOM 666 C CA . ASN A 1 90 ? -48.395 -23.618 79.785 1.00 27.04 ? 110 ASN A CA 1 ATOM 667 C C . ASN A 1 90 ? -48.440 -22.299 79.019 1.00 26.36 ? 110 ASN A C 1 ATOM 668 O O . ASN A 1 90 ? -48.708 -21.248 79.595 1.00 26.10 ? 110 ASN A O 1 ATOM 669 C CB . ASN A 1 90 ? -49.474 -24.615 79.306 1.00 27.00 ? 110 ASN A CB 1 ATOM 670 C CG . ASN A 1 90 ? -50.857 -23.991 79.136 1.00 27.80 ? 110 ASN A CG 1 ATOM 671 O OD1 . ASN A 1 90 ? -51.007 -22.907 78.560 1.00 26.07 ? 110 ASN A OD1 1 ATOM 672 N ND2 . ASN A 1 90 ? -51.884 -24.699 79.618 1.00 29.49 ? 110 ASN A ND2 1 ATOM 673 N N . VAL A 1 91 ? -48.141 -22.366 77.727 1.00 25.85 ? 111 VAL A N 1 ATOM 674 C CA . VAL A 1 91 ? -48.364 -21.254 76.816 1.00 25.22 ? 111 VAL A CA 1 ATOM 675 C C . VAL A 1 91 ? -49.529 -21.631 75.920 1.00 25.12 ? 111 VAL A C 1 ATOM 676 O O . VAL A 1 91 ? -49.536 -22.706 75.343 1.00 25.34 ? 111 VAL A O 1 ATOM 677 C CB . VAL A 1 91 ? -47.134 -20.986 75.947 1.00 25.04 ? 111 VAL A CB 1 ATOM 678 C CG1 . VAL A 1 91 ? -47.407 -19.849 74.959 1.00 24.00 ? 111 VAL A CG1 1 ATOM 679 C CG2 . VAL A 1 91 ? -45.926 -20.677 76.824 1.00 24.46 ? 111 VAL A CG2 1 ATOM 680 N N . THR A 1 92 ? -50.508 -20.746 75.805 1.00 25.08 ? 112 THR A N 1 ATOM 681 C CA . THR A 1 92 ? -51.649 -20.938 74.910 1.00 25.24 ? 112 THR A CA 1 ATOM 682 C C . THR A 1 92 ? -51.796 -19.697 74.043 1.00 24.98 ? 112 THR A C 1 ATOM 683 O O . THR A 1 92 ? -51.639 -18.574 74.538 1.00 25.51 ? 112 THR A O 1 ATOM 684 C CB . THR A 1 92 ? -52.964 -21.103 75.706 1.00 25.44 ? 112 THR A CB 1 ATOM 685 O OG1 . THR A 1 92 ? -52.798 -22.112 76.709 1.00 26.83 ? 112 THR A OG1 1 ATOM 686 C CG2 . THR A 1 92 ? -54.121 -21.477 74.786 1.00 25.17 ? 112 THR A CG2 1 ATOM 687 N N . GLU A 1 93 ? -52.096 -19.892 72.763 1.00 24.53 ? 113 GLU A N 1 ATOM 688 C CA . GLU A 1 93 ? -52.339 -18.783 71.856 1.00 24.62 ? 113 GLU A CA 1 ATOM 689 C C . GLU A 1 93 ? -53.828 -18.669 71.561 1.00 24.80 ? 113 GLU A C 1 ATOM 690 O O . GLU A 1 93 ? -54.547 -19.661 71.591 1.00 24.89 ? 113 GLU A O 1 ATOM 691 C CB . GLU A 1 93 ? -51.555 -18.950 70.547 1.00 24.30 ? 113 GLU A CB 1 ATOM 692 C CG . GLU A 1 93 ? -50.038 -19.071 70.770 1.00 23.46 ? 113 GLU A CG 1 ATOM 693 C CD . GLU A 1 93 ? -49.221 -18.763 69.532 1.00 22.49 ? 113 GLU A CD 1 ATOM 694 O OE1 . GLU A 1 93 ? -49.794 -18.290 68.519 1.00 20.61 ? 113 GLU A OE1 1 ATOM 695 O OE2 . GLU A 1 93 ? -47.986 -18.969 69.579 1.00 22.41 ? 113 GLU A OE2 1 ATOM 696 N N . PHE A 1 94 ? -54.276 -17.447 71.295 1.00 24.95 ? 114 PHE A N 1 ATOM 697 C CA . PHE A 1 94 ? -55.649 -17.200 70.859 1.00 25.77 ? 114 PHE A CA 1 ATOM 698 C C . PHE A 1 94 ? -55.653 -16.279 69.660 1.00 25.92 ? 114 PHE A C 1 ATOM 699 O O . PHE A 1 94 ? -54.694 -15.549 69.423 1.00 26.43 ? 114 PHE A O 1 ATOM 700 C CB . PHE A 1 94 ? -56.484 -16.579 71.990 1.00 25.65 ? 114 PHE A CB 1 ATOM 701 C CG . PHE A 1 94 ? -56.540 -17.427 73.236 1.00 26.33 ? 114 PHE A CG 1 ATOM 702 C CD1 . PHE A 1 94 ? -55.497 -17.405 74.153 1.00 26.86 ? 114 PHE A CD1 1 ATOM 703 C CD2 . PHE A 1 94 ? -57.635 -18.244 73.487 1.00 26.73 ? 114 PHE A CD2 1 ATOM 704 C CE1 . PHE A 1 94 ? -55.541 -18.191 75.305 1.00 27.55 ? 114 PHE A CE1 1 ATOM 705 C CE2 . PHE A 1 94 ? -57.689 -19.027 74.630 1.00 27.49 ? 114 PHE A CE2 1 ATOM 706 C CZ . PHE A 1 94 ? -56.633 -19.011 75.537 1.00 27.39 ? 114 PHE A CZ 1 ATOM 707 N N . ALA A 1 95 ? -56.730 -16.347 68.890 1.00 26.48 ? 115 ALA A N 1 ATOM 708 C CA . ALA A 1 95 ? -57.031 -15.349 67.882 1.00 26.71 ? 115 ALA A CA 1 ATOM 709 C C . ALA A 1 95 ? -58.119 -14.465 68.466 1.00 27.01 ? 115 ALA A C 1 ATOM 710 O O . ALA A 1 95 ? -59.205 -14.946 68.786 1.00 27.14 ? 115 ALA A O 1 ATOM 711 C CB . ALA A 1 95 ? -57.501 -16.008 66.597 1.00 26.54 ? 115 ALA A CB 1 ATOM 712 N N . VAL A 1 96 ? -57.813 -13.180 68.625 1.00 27.38 ? 116 VAL A N 1 ATOM 713 C CA . VAL A 1 96 ? -58.757 -12.205 69.154 1.00 27.35 ? 116 VAL A CA 1 ATOM 714 C C . VAL A 1 96 ? -59.353 -11.377 68.014 1.00 27.64 ? 116 VAL A C 1 ATOM 715 O O . VAL A 1 96 ? -58.636 -10.860 67.140 1.00 26.92 ? 116 VAL A O 1 ATOM 716 C CB . VAL A 1 96 ? -58.088 -11.275 70.186 1.00 27.33 ? 116 VAL A CB 1 ATOM 717 C CG1 . VAL A 1 96 ? -59.097 -10.265 70.734 1.00 26.78 ? 116 VAL A CG1 1 ATOM 718 C CG2 . VAL A 1 96 ? -57.466 -12.091 71.312 1.00 27.40 ? 116 VAL A CG2 1 ATOM 719 N N . GLY A 1 97 ? -60.675 -11.260 68.019 1.00 28.01 ? 117 GLY A N 1 ATOM 720 C CA . GLY A 1 97 ? -61.367 -10.463 67.011 1.00 28.43 ? 117 GLY A CA 1 ATOM 721 C C . GLY A 1 97 ? -62.817 -10.197 67.378 1.00 28.66 ? 117 GLY A C 1 ATOM 722 O O . GLY A 1 97 ? -63.258 -10.589 68.458 1.00 28.71 ? 117 GLY A O 1 ATOM 723 N N . PRO A 1 98 ? -63.560 -9.499 66.494 1.00 28.94 ? 118 PRO A N 1 ATOM 724 C CA . PRO A 1 98 ? -63.021 -8.878 65.288 1.00 28.62 ? 118 PRO A CA 1 ATOM 725 C C . PRO A 1 98 ? -62.376 -7.542 65.618 1.00 28.77 ? 118 PRO A C 1 ATOM 726 O O . PRO A 1 98 ? -62.493 -7.047 66.747 1.00 28.31 ? 118 PRO A O 1 ATOM 727 C CB . PRO A 1 98 ? -64.259 -8.676 64.410 1.00 28.82 ? 118 PRO A CB 1 ATOM 728 C CG . PRO A 1 98 ? -65.386 -8.487 65.381 1.00 28.84 ? 118 PRO A CG 1 ATOM 729 C CD . PRO A 1 98 ? -65.006 -9.243 66.645 1.00 29.00 ? 118 PRO A CD 1 ATOM 730 N N . LEU A 1 99 ? -61.675 -6.975 64.643 1.00 28.95 ? 119 LEU A N 1 ATOM 731 C CA . LEU A 1 99 ? -61.098 -5.653 64.798 1.00 29.12 ? 119 LEU A CA 1 ATOM 732 C C . LEU A 1 99 ? -61.660 -4.777 63.689 1.00 29.71 ? 119 LEU A C 1 ATOM 733 O O . LEU A 1 99 ? -61.537 -5.118 62.507 1.00 29.37 ? 119 LEU A O 1 ATOM 734 C CB . LEU A 1 99 ? -59.578 -5.695 64.733 1.00 29.17 ? 119 LEU A CB 1 ATOM 735 C CG . LEU A 1 99 ? -58.843 -6.388 65.882 1.00 29.40 ? 119 LEU A CG 1 ATOM 736 C CD1 . LEU A 1 99 ? -57.337 -6.471 65.575 1.00 28.72 ? 119 LEU A CD1 1 ATOM 737 C CD2 . LEU A 1 99 ? -59.079 -5.673 67.198 1.00 29.46 ? 119 LEU A CD2 1 ATOM 738 N N . PRO A 1 100 ? -62.295 -3.652 64.058 1.00 30.36 ? 120 PRO A N 1 ATOM 739 C CA . PRO A 1 100 ? -62.493 -3.160 65.423 1.00 30.83 ? 120 PRO A CA 1 ATOM 740 C C . PRO A 1 100 ? -63.576 -3.924 66.201 1.00 31.31 ? 120 PRO A C 1 ATOM 741 O O . PRO A 1 100 ? -64.360 -4.669 65.608 1.00 31.69 ? 120 PRO A O 1 ATOM 742 C CB . PRO A 1 100 ? -62.927 -1.710 65.202 1.00 30.89 ? 120 PRO A CB 1 ATOM 743 C CG . PRO A 1 100 ? -63.645 -1.741 63.879 1.00 30.94 ? 120 PRO A CG 1 ATOM 744 C CD . PRO A 1 100 ? -62.893 -2.752 63.052 1.00 30.49 ? 120 PRO A CD 1 ATOM 745 N N . GLY A 1 101 ? -63.591 -3.730 67.517 1.00 31.76 ? 121 GLY A N 1 ATOM 746 C CA . GLY A 1 101 ? -64.636 -4.258 68.398 1.00 32.22 ? 121 GLY A CA 1 ATOM 747 C C . GLY A 1 101 ? -64.453 -5.702 68.832 1.00 32.46 ? 121 GLY A C 1 ATOM 748 O O . GLY A 1 101 ? -65.325 -6.527 68.586 1.00 32.60 ? 121 GLY A O 1 ATOM 749 N N . PRO A 1 102 ? -63.321 -6.023 69.484 1.00 32.73 ? 122 PRO A N 1 ATOM 750 C CA . PRO A 1 102 ? -63.084 -7.426 69.827 1.00 33.34 ? 122 PRO A CA 1 ATOM 751 C C . PRO A 1 102 ? -64.142 -8.007 70.775 1.00 33.75 ? 122 PRO A C 1 ATOM 752 O O . PRO A 1 102 ? -64.476 -7.369 71.775 1.00 34.16 ? 122 PRO A O 1 ATOM 753 C CB . PRO A 1 102 ? -61.686 -7.409 70.482 1.00 33.17 ? 122 PRO A CB 1 ATOM 754 C CG . PRO A 1 102 ? -61.405 -5.986 70.800 1.00 33.00 ? 122 PRO A CG 1 ATOM 755 C CD . PRO A 1 102 ? -62.172 -5.167 69.824 1.00 32.61 ? 122 PRO A CD 1 ATOM 756 N N A CYS A 1 103 ? -64.674 -9.182 70.421 0.50 34.03 ? 123 CYS A N 1 ATOM 757 N N B CYS A 1 103 ? -64.649 -9.197 70.459 0.50 33.92 ? 123 CYS A N 1 ATOM 758 C CA A CYS A 1 103 ? -65.677 -9.903 71.226 0.50 34.24 ? 123 CYS A CA 1 ATOM 759 C CA B CYS A 1 103 ? -65.638 -9.872 71.306 0.50 34.03 ? 123 CYS A CA 1 ATOM 760 C C A CYS A 1 103 ? -65.236 -11.297 71.669 0.50 34.26 ? 123 CYS A C 1 ATOM 761 C C B CYS A 1 103 ? -65.422 -11.382 71.473 0.50 34.10 ? 123 CYS A C 1 ATOM 762 O O A CYS A 1 103 ? -65.701 -11.790 72.699 0.50 34.40 ? 123 CYS A O 1 ATOM 763 O O B CYS A 1 103 ? -66.256 -12.052 72.088 0.50 34.04 ? 123 CYS A O 1 ATOM 764 C CB A CYS A 1 103 ? -66.973 -10.094 70.438 0.50 34.26 ? 123 CYS A CB 1 ATOM 765 C CB B CYS A 1 103 ? -67.039 -9.647 70.740 0.50 34.05 ? 123 CYS A CB 1 ATOM 766 S SG A CYS A 1 103 ? -67.483 -8.702 69.449 0.50 34.93 ? 123 CYS A SG 1 ATOM 767 S SG B CYS A 1 103 ? -67.385 -10.651 69.283 0.50 34.20 ? 123 CYS A SG 1 ATOM 768 N N . TYR A 1 104 ? -64.351 -11.928 70.900 1.00 34.10 ? 124 TYR A N 1 ATOM 769 C CA . TYR A 1 104 ? -64.004 -13.334 71.102 1.00 34.21 ? 124 TYR A CA 1 ATOM 770 C C . TYR A 1 104 ? -62.497 -13.561 71.184 1.00 34.46 ? 124 TYR A C 1 ATOM 771 O O . TYR A 1 104 ? -61.700 -12.801 70.622 1.00 34.28 ? 124 TYR A O 1 ATOM 772 C CB . TYR A 1 104 ? -64.593 -14.195 69.973 1.00 34.20 ? 124 TYR A CB 1 ATOM 773 C CG . TYR A 1 104 ? -64.040 -13.915 68.580 1.00 34.16 ? 124 TYR A CG 1 ATOM 774 C CD1 . TYR A 1 104 ? -62.779 -14.386 68.192 1.00 33.79 ? 124 TYR A CD1 1 ATOM 775 C CD2 . TYR A 1 104 ? -64.790 -13.210 67.641 1.00 33.24 ? 124 TYR A CD2 1 ATOM 776 C CE1 . TYR A 1 104 ? -62.276 -14.145 66.914 1.00 33.62 ? 124 TYR A CE1 1 ATOM 777 C CE2 . TYR A 1 104 ? -64.290 -12.957 66.361 1.00 32.84 ? 124 TYR A CE2 1 ATOM 778 C CZ . TYR A 1 104 ? -63.036 -13.431 66.004 1.00 33.10 ? 124 TYR A CZ 1 ATOM 779 O OH . TYR A 1 104 ? -62.541 -13.182 64.744 1.00 32.27 ? 124 TYR A OH 1 ATOM 780 N N . MET A 1 105 ? -62.125 -14.611 71.910 1.00 34.71 ? 125 MET A N 1 ATOM 781 C CA . MET A 1 105 ? -60.802 -15.192 71.811 1.00 34.79 ? 125 MET A CA 1 ATOM 782 C C . MET A 1 105 ? -60.968 -16.689 71.534 1.00 34.94 ? 125 MET A C 1 ATOM 783 O O . MET A 1 105 ? -61.509 -17.427 72.366 1.00 35.42 ? 125 MET A O 1 ATOM 784 C CB . MET A 1 105 ? -59.978 -14.920 73.069 1.00 34.96 ? 125 MET A CB 1 ATOM 785 C CG . MET A 1 105 ? -60.566 -15.424 74.372 1.00 35.24 ? 125 MET A CG 1 ATOM 786 S SD . MET A 1 105 ? -59.688 -14.738 75.777 1.00 35.99 ? 125 MET A SD 1 ATOM 787 C CE . MET A 1 105 ? -58.136 -15.641 75.725 1.00 35.48 ? 125 MET A CE 1 ATOM 788 N N . ARG A 1 106 ? -60.538 -17.120 70.345 1.00 34.56 ? 126 ARG A N 1 ATOM 789 C CA . ARG A 1 106 ? -60.607 -18.533 69.940 1.00 34.30 ? 126 ARG A CA 1 ATOM 790 C C . ARG A 1 106 ? -59.219 -19.172 69.938 1.00 33.82 ? 126 ARG A C 1 ATOM 791 O O . ARG A 1 106 ? -58.205 -18.477 69.832 1.00 33.64 ? 126 ARG A O 1 ATOM 792 C CB . ARG A 1 106 ? -61.243 -18.675 68.553 1.00 34.33 ? 126 ARG A CB 1 ATOM 793 C CG . ARG A 1 106 ? -60.437 -18.058 67.409 1.00 35.49 ? 126 ARG A CG 1 ATOM 794 C CD . ARG A 1 106 ? -61.175 -18.139 66.067 1.00 36.63 ? 126 ARG A CD 1 ATOM 795 N NE . ARG A 1 106 ? -60.374 -17.558 64.987 1.00 37.20 ? 126 ARG A NE 1 ATOM 796 C CZ . ARG A 1 106 ? -59.349 -18.167 64.389 1.00 38.32 ? 126 ARG A CZ 1 ATOM 797 N NH1 . ARG A 1 106 ? -58.983 -19.395 64.748 1.00 38.58 ? 126 ARG A NH1 1 ATOM 798 N NH2 . ARG A 1 106 ? -58.676 -17.547 63.423 1.00 38.62 ? 126 ARG A NH2 1 ATOM 799 N N . ALA A 1 107 ? -59.187 -20.501 70.029 1.00 33.12 ? 127 ALA A N 1 ATOM 800 C CA . ALA A 1 107 ? -57.935 -21.255 70.085 1.00 32.69 ? 127 ALA A CA 1 ATOM 801 C C . ALA A 1 107 ? -57.128 -21.050 68.812 1.00 32.24 ? 127 ALA A C 1 ATOM 802 O O . ALA A 1 107 ? -57.687 -20.943 67.721 1.00 32.30 ? 127 ALA A O 1 ATOM 803 C CB . ALA A 1 107 ? -58.205 -22.744 70.307 1.00 32.38 ? 127 ALA A CB 1 ATOM 804 N N . LEU A 1 108 ? -55.813 -20.970 68.965 1.00 31.77 ? 128 LEU A N 1 ATOM 805 C CA . LEU A 1 108 ? -54.919 -20.742 67.839 1.00 31.49 ? 128 LEU A CA 1 ATOM 806 C C . LEU A 1 108 ? -53.707 -21.646 67.993 1.00 31.77 ? 128 LEU A C 1 ATOM 807 O O . LEU A 1 108 ? -53.120 -21.710 69.067 1.00 31.31 ? 128 LEU A O 1 ATOM 808 C CB . LEU A 1 108 ? -54.480 -19.275 67.797 1.00 30.88 ? 128 LEU A CB 1 ATOM 809 C CG . LEU A 1 108 ? -53.639 -18.875 66.583 1.00 30.52 ? 128 LEU A CG 1 ATOM 810 C CD1 . LEU A 1 108 ? -54.453 -19.030 65.305 1.00 28.46 ? 128 LEU A CD1 1 ATOM 811 C CD2 . LEU A 1 108 ? -53.081 -17.457 66.714 1.00 28.40 ? 128 LEU A CD2 1 ATOM 812 N N . SER A 1 109 ? -53.357 -22.358 66.923 1.00 32.38 ? 129 SER A N 1 ATOM 813 C CA . SER A 1 109 ? -52.232 -23.295 66.943 1.00 32.81 ? 129 SER A CA 1 ATOM 814 C C . SER A 1 109 ? -52.252 -24.212 68.175 1.00 32.53 ? 129 SER A C 1 ATOM 815 O O . SER A 1 109 ? -51.233 -24.364 68.850 1.00 32.53 ? 129 SER A O 1 ATOM 816 C CB . SER A 1 109 ? -50.913 -22.513 66.896 1.00 32.91 ? 129 SER A CB 1 ATOM 817 O OG . SER A 1 109 ? -50.960 -21.502 65.901 1.00 34.79 ? 129 SER A OG 1 ATOM 818 N N . PRO A 1 110 ? -53.417 -24.806 68.490 1.00 32.54 ? 130 PRO A N 1 ATOM 819 C CA . PRO A 1 110 ? -53.447 -25.693 69.651 1.00 32.57 ? 130 PRO A CA 1 ATOM 820 C C . PRO A 1 110 ? -52.605 -26.938 69.389 1.00 32.64 ? 130 PRO A C 1 ATOM 821 O O . PRO A 1 110 ? -52.573 -27.432 68.261 1.00 33.09 ? 130 PRO A O 1 ATOM 822 C CB . PRO A 1 110 ? -54.925 -26.052 69.784 1.00 32.45 ? 130 PRO A CB 1 ATOM 823 C CG . PRO A 1 110 ? -55.467 -25.914 68.400 1.00 32.83 ? 130 PRO A CG 1 ATOM 824 C CD . PRO A 1 110 ? -54.695 -24.812 67.751 1.00 32.43 ? 130 PRO A CD 1 ATOM 825 N N . ARG A 1 111 ? -51.916 -27.420 70.414 1.00 32.42 ? 131 ARG A N 1 ATOM 826 C CA . ARG A 1 111 ? -51.052 -28.588 70.280 1.00 32.46 ? 131 ARG A CA 1 ATOM 827 C C . ARG A 1 111 ? -51.356 -29.558 71.421 1.00 32.65 ? 131 ARG A C 1 ATOM 828 O O . ARG A 1 111 ? -50.509 -29.807 72.278 1.00 32.67 ? 131 ARG A O 1 ATOM 829 C CB . ARG A 1 111 ? -49.576 -28.159 70.280 1.00 32.20 ? 131 ARG A CB 1 ATOM 830 C CG . ARG A 1 111 ? -48.620 -29.225 69.778 1.00 31.65 ? 131 ARG A CG 1 ATOM 831 C CD . ARG A 1 111 ? -47.160 -28.767 69.830 1.00 30.85 ? 131 ARG A CD 1 ATOM 832 N NE . ARG A 1 111 ? -46.256 -29.879 69.533 1.00 30.45 ? 131 ARG A NE 1 ATOM 833 C CZ . ARG A 1 111 ? -44.935 -29.867 69.700 1.00 30.07 ? 131 ARG A CZ 1 ATOM 834 N NH1 . ARG A 1 111 ? -44.311 -28.787 70.163 1.00 29.80 ? 131 ARG A NH1 1 ATOM 835 N NH2 . ARG A 1 111 ? -44.227 -30.953 69.407 1.00 29.69 ? 131 ARG A NH2 1 ATOM 836 N N . PRO A 1 112 ? -52.585 -30.108 71.438 1.00 32.91 ? 132 PRO A N 1 ATOM 837 C CA . PRO A 1 112 ? -52.987 -30.983 72.538 1.00 33.06 ? 132 PRO A CA 1 ATOM 838 C C . PRO A 1 112 ? -52.125 -32.246 72.619 1.00 33.00 ? 132 PRO A C 1 ATOM 839 O O . PRO A 1 112 ? -51.755 -32.813 71.593 1.00 33.44 ? 132 PRO A O 1 ATOM 840 C CB . PRO A 1 112 ? -54.439 -31.327 72.190 1.00 33.32 ? 132 PRO A CB 1 ATOM 841 C CG . PRO A 1 112 ? -54.492 -31.230 70.708 1.00 32.79 ? 132 PRO A CG 1 ATOM 842 C CD . PRO A 1 112 ? -53.618 -30.049 70.389 1.00 32.86 ? 132 PRO A CD 1 ATOM 843 N N . GLY A 1 113 ? -51.802 -32.667 73.834 1.00 32.89 ? 133 GLY A N 1 ATOM 844 C CA . GLY A 1 113 ? -50.932 -33.819 74.044 1.00 32.80 ? 133 GLY A CA 1 ATOM 845 C C . GLY A 1 113 ? -49.445 -33.507 74.142 1.00 32.49 ? 133 GLY A C 1 ATOM 846 O O . GLY A 1 113 ? -48.644 -34.410 74.407 1.00 33.14 ? 133 GLY A O 1 ATOM 847 N N . TYR A 1 114 ? -49.067 -32.247 73.926 1.00 31.83 ? 134 TYR A N 1 ATOM 848 C CA . TYR A 1 114 ? -47.679 -31.803 74.091 1.00 31.27 ? 134 TYR A CA 1 ATOM 849 C C . TYR A 1 114 ? -47.598 -31.156 75.453 1.00 31.41 ? 134 TYR A C 1 ATOM 850 O O . TYR A 1 114 ? -48.481 -30.386 75.827 1.00 31.35 ? 134 TYR A O 1 ATOM 851 C CB . TYR A 1 114 ? -47.304 -30.804 72.993 1.00 31.05 ? 134 TYR A CB 1 ATOM 852 C CG . TYR A 1 114 ? -45.979 -30.083 73.163 1.00 29.25 ? 134 TYR A CG 1 ATOM 853 C CD1 . TYR A 1 114 ? -45.943 -28.707 73.401 1.00 28.14 ? 134 TYR A CD1 1 ATOM 854 C CD2 . TYR A 1 114 ? -44.762 -30.758 73.043 1.00 28.28 ? 134 TYR A CD2 1 ATOM 855 C CE1 . TYR A 1 114 ? -44.741 -28.023 73.534 1.00 26.74 ? 134 TYR A CE1 1 ATOM 856 C CE2 . TYR A 1 114 ? -43.538 -30.073 73.171 1.00 27.52 ? 134 TYR A CE2 1 ATOM 857 C CZ . TYR A 1 114 ? -43.540 -28.710 73.419 1.00 26.77 ? 134 TYR A CZ 1 ATOM 858 O OH . TYR A 1 114 ? -42.353 -28.017 73.545 1.00 26.66 ? 134 TYR A OH 1 ATOM 859 N N . GLN A 1 115 ? -46.546 -31.468 76.196 1.00 31.46 ? 135 GLN A N 1 ATOM 860 C CA . GLN A 1 115 ? -46.474 -31.084 77.598 1.00 31.63 ? 135 GLN A CA 1 ATOM 861 C C . GLN A 1 115 ? -45.353 -30.100 77.934 1.00 31.25 ? 135 GLN A C 1 ATOM 862 O O . GLN A 1 115 ? -45.318 -29.577 79.049 1.00 31.45 ? 135 GLN A O 1 ATOM 863 C CB . GLN A 1 115 ? -46.344 -32.345 78.463 1.00 31.88 ? 135 GLN A CB 1 ATOM 864 C CG . GLN A 1 115 ? -47.607 -33.215 78.476 1.00 32.39 ? 135 GLN A CG 1 ATOM 865 C CD . GLN A 1 115 ? -47.762 -34.016 79.764 1.00 33.64 ? 135 GLN A CD 1 ATOM 866 N N . SER A 1 116 ? -44.464 -29.818 76.981 1.00 30.50 ? 136 SER A N 1 ATOM 867 C CA . SER A 1 116 ? -43.309 -28.969 77.253 1.00 29.92 ? 136 SER A CA 1 ATOM 868 C C . SER A 1 116 ? -43.491 -27.506 76.819 1.00 29.15 ? 136 SER A C 1 ATOM 869 O O . SER A 1 116 ? -42.497 -26.800 76.625 1.00 29.21 ? 136 SER A O 1 ATOM 870 C CB . SER A 1 116 ? -42.058 -29.556 76.592 1.00 29.87 ? 136 SER A CB 1 ATOM 871 O OG . SER A 1 116 ? -41.687 -30.775 77.199 1.00 30.79 ? 136 SER A OG 1 ATOM 872 N N . SER A 1 117 ? -44.727 -27.023 76.686 1.00 28.21 ? 137 SER A N 1 ATOM 873 C CA . SER A 1 117 ? -44.913 -25.654 76.178 1.00 27.31 ? 137 SER A CA 1 ATOM 874 C C . SER A 1 117 ? -44.288 -24.604 77.099 1.00 26.85 ? 137 SER A C 1 ATOM 875 O O . SER A 1 117 ? -43.683 -23.641 76.613 1.00 26.71 ? 137 SER A O 1 ATOM 876 C CB . SER A 1 117 ? -46.378 -25.330 75.884 1.00 27.34 ? 137 SER A CB 1 ATOM 877 O OG . SER A 1 117 ? -47.162 -25.271 77.050 1.00 26.89 ? 137 SER A OG 1 ATOM 878 N N . TRP A 1 118 ? -44.389 -24.797 78.415 1.00 26.09 ? 138 TRP A N 1 ATOM 879 C CA . TRP A 1 118 ? -43.821 -23.824 79.345 1.00 25.75 ? 138 TRP A CA 1 ATOM 880 C C . TRP A 1 118 ? -42.303 -23.762 79.168 1.00 25.30 ? 138 TRP A C 1 ATOM 881 O O . TRP A 1 118 ? -41.741 -22.668 79.045 1.00 25.19 ? 138 TRP A O 1 ATOM 882 C CB . TRP A 1 118 ? -44.211 -24.119 80.807 1.00 25.71 ? 138 TRP A CB 1 ATOM 883 C CG . TRP A 1 118 ? -43.872 -22.998 81.767 1.00 24.76 ? 138 TRP A CG 1 ATOM 884 C CD1 . TRP A 1 118 ? -42.892 -23.004 82.724 1.00 24.95 ? 138 TRP A CD1 1 ATOM 885 C CD2 . TRP A 1 118 ? -44.497 -21.714 81.850 1.00 24.75 ? 138 TRP A CD2 1 ATOM 886 N NE1 . TRP A 1 118 ? -42.876 -21.810 83.399 1.00 24.08 ? 138 TRP A NE1 1 ATOM 887 C CE2 . TRP A 1 118 ? -43.851 -20.999 82.885 1.00 25.11 ? 138 TRP A CE2 1 ATOM 888 C CE3 . TRP A 1 118 ? -45.550 -21.097 81.156 1.00 25.77 ? 138 TRP A CE3 1 ATOM 889 C CZ2 . TRP A 1 118 ? -44.218 -19.698 83.239 1.00 24.34 ? 138 TRP A CZ2 1 ATOM 890 C CZ3 . TRP A 1 118 ? -45.919 -19.805 81.514 1.00 25.03 ? 138 TRP A CZ3 1 ATOM 891 C CH2 . TRP A 1 118 ? -45.254 -19.122 82.545 1.00 25.47 ? 138 TRP A CH2 1 ATOM 892 N N . ALA A 1 119 ? -41.649 -24.925 79.119 1.00 24.53 ? 139 ALA A N 1 ATOM 893 C CA . ALA A 1 119 ? -40.197 -24.965 78.911 1.00 24.45 ? 139 ALA A CA 1 ATOM 894 C C . ALA A 1 119 ? -39.789 -24.377 77.546 1.00 24.15 ? 139 ALA A C 1 ATOM 895 O O . ALA A 1 119 ? -38.679 -23.853 77.400 1.00 23.87 ? 139 ALA A O 1 ATOM 896 C CB . ALA A 1 119 ? -39.663 -26.387 79.067 1.00 24.68 ? 139 ALA A CB 1 ATOM 897 N N . SER A 1 120 ? -40.686 -24.446 76.561 1.00 23.64 ? 140 SER A N 1 ATOM 898 C CA . SER A 1 120 ? -40.383 -23.944 75.214 1.00 23.67 ? 140 SER A CA 1 ATOM 899 C C . SER A 1 120 ? -40.476 -22.423 75.088 1.00 23.29 ? 140 SER A C 1 ATOM 900 O O . SER A 1 120 ? -40.025 -21.871 74.101 1.00 23.50 ? 140 SER A O 1 ATOM 901 C CB . SER A 1 120 ? -41.327 -24.552 74.178 1.00 23.46 ? 140 SER A CB 1 ATOM 902 O OG . SER A 1 120 ? -42.601 -23.921 74.213 1.00 23.65 ? 140 SER A OG 1 ATOM 903 N N . ARG A 1 121 ? -41.087 -21.758 76.066 1.00 22.95 ? 141 ARG A N 1 ATOM 904 C CA . ARG A 1 121 ? -41.423 -20.345 75.928 1.00 22.79 ? 141 ARG A CA 1 ATOM 905 C C . ARG A 1 121 ? -40.162 -19.474 75.885 1.00 22.54 ? 141 ARG A C 1 ATOM 906 O O . ARG A 1 121 ? -39.132 -19.837 76.468 1.00 21.92 ? 141 ARG A O 1 ATOM 907 C CB . ARG A 1 121 ? -42.384 -19.887 77.043 1.00 23.01 ? 141 ARG A CB 1 ATOM 908 C CG . ARG A 1 121 ? -41.718 -19.408 78.316 1.00 22.78 ? 141 ARG A CG 1 ATOM 909 C CD . ARG A 1 121 ? -42.677 -19.358 79.493 1.00 24.45 ? 141 ARG A CD 1 ATOM 910 N NE . ARG A 1 121 ? -41.985 -18.883 80.695 1.00 24.19 ? 141 ARG A NE 1 ATOM 911 C CZ . ARG A 1 121 ? -41.172 -19.622 81.449 1.00 23.97 ? 141 ARG A CZ 1 ATOM 912 N NH1 . ARG A 1 121 ? -40.951 -20.893 81.155 1.00 23.50 ? 141 ARG A NH1 1 ATOM 913 N NH2 . ARG A 1 121 ? -40.580 -19.087 82.516 1.00 24.48 ? 141 ARG A NH2 1 ATOM 914 N N . PRO A 1 122 ? -40.238 -18.331 75.175 1.00 22.52 ? 142 PRO A N 1 ATOM 915 C CA . PRO A 1 122 ? -39.133 -17.378 75.166 1.00 22.67 ? 142 PRO A CA 1 ATOM 916 C C . PRO A 1 122 ? -38.806 -16.857 76.550 1.00 23.26 ? 142 PRO A C 1 ATOM 917 O O . PRO A 1 122 ? -39.677 -16.831 77.443 1.00 22.79 ? 142 PRO A O 1 ATOM 918 C CB . PRO A 1 122 ? -39.671 -16.227 74.308 1.00 22.59 ? 142 PRO A CB 1 ATOM 919 C CG . PRO A 1 122 ? -40.635 -16.876 73.395 1.00 21.85 ? 142 PRO A CG 1 ATOM 920 C CD . PRO A 1 122 ? -41.302 -17.924 74.234 1.00 22.38 ? 142 PRO A CD 1 ATOM 921 N N . ILE A 1 123 ? -37.554 -16.448 76.712 1.00 23.47 ? 143 ILE A N 1 ATOM 922 C CA . ILE A 1 123 ? -37.114 -15.766 77.912 1.00 24.11 ? 143 ILE A CA 1 ATOM 923 C C . ILE A 1 123 ? -37.753 -14.372 77.940 1.00 24.66 ? 143 ILE A C 1 ATOM 924 O O . ILE A 1 123 ? -38.272 -13.903 76.935 1.00 24.37 ? 143 ILE A O 1 ATOM 925 C CB . ILE A 1 123 ? -35.574 -15.690 77.962 1.00 24.17 ? 143 ILE A CB 1 ATOM 926 C CG1 . ILE A 1 123 ? -35.080 -15.348 79.375 1.00 24.30 ? 143 ILE A CG1 1 ATOM 927 C CG2 . ILE A 1 123 ? -35.057 -14.682 76.929 1.00 24.35 ? 143 ILE A CG2 1 ATOM 928 C CD1 . ILE A 1 123 ? -33.785 -16.016 79.741 1.00 24.00 ? 143 ILE A CD1 1 ATOM 929 N N . SER A 1 124 ? -37.737 -13.729 79.104 1.00 25.36 ? 144 SER A N 1 ATOM 930 C CA . SER A 1 124 ? -38.385 -12.433 79.283 1.00 25.43 ? 144 SER A CA 1 ATOM 931 C C . SER A 1 124 ? -37.583 -11.562 80.241 1.00 25.89 ? 144 SER A C 1 ATOM 932 O O . SER A 1 124 ? -36.719 -12.052 80.976 1.00 25.87 ? 144 SER A O 1 ATOM 933 C CB . SER A 1 124 ? -39.814 -12.626 79.807 1.00 25.52 ? 144 SER A CB 1 ATOM 934 O OG . SER A 1 124 ? -39.811 -13.221 81.091 1.00 24.80 ? 144 SER A OG 1 ATOM 935 N N . THR A 1 125 ? -37.866 -10.266 80.218 1.00 26.45 ? 145 THR A N 1 ATOM 936 C CA . THR A 1 125 ? -37.199 -9.318 81.110 1.00 26.67 ? 145 THR A CA 1 ATOM 937 C C . THR A 1 125 ? -37.354 -9.712 82.580 1.00 26.63 ? 145 THR A C 1 ATOM 938 O O . THR A 1 125 ? -36.389 -9.657 83.348 1.00 26.80 ? 145 THR A O 1 ATOM 939 C CB . THR A 1 125 ? -37.706 -7.887 80.868 1.00 26.62 ? 145 THR A CB 1 ATOM 940 O OG1 . THR A 1 125 ? -37.283 -7.472 79.568 1.00 27.73 ? 145 THR A OG1 1 ATOM 941 C CG2 . THR A 1 125 ? -37.133 -6.915 81.882 1.00 26.92 ? 145 THR A CG2 1 ATOM 942 N N . ALA A 1 126 ? -38.553 -10.133 82.969 1.00 26.51 ? 146 ALA A N 1 ATOM 943 C CA . ALA A 1 126 ? -38.786 -10.548 84.358 1.00 26.42 ? 146 ALA A CA 1 ATOM 944 C C . ALA A 1 126 ? -37.866 -11.716 84.717 1.00 26.39 ? 146 ALA A C 1 ATOM 945 O O . ALA A 1 126 ? -37.270 -11.741 85.797 1.00 26.06 ? 146 ALA A O 1 ATOM 946 C CB . ALA A 1 126 ? -40.255 -10.916 84.579 1.00 25.97 ? 146 ALA A CB 1 ATOM 947 N N . GLU A 1 127 ? -37.739 -12.665 83.787 1.00 26.52 ? 147 GLU A N 1 ATOM 948 C CA . GLU A 1 127 ? -36.919 -13.847 84.005 1.00 26.40 ? 147 GLU A CA 1 ATOM 949 C C . GLU A 1 127 ? -35.456 -13.463 84.122 1.00 26.30 ? 147 GLU A C 1 ATOM 950 O O . GLU A 1 127 ? -34.748 -13.989 84.978 1.00 27.03 ? 147 GLU A O 1 ATOM 951 C CB . GLU A 1 127 ? -37.118 -14.878 82.881 1.00 26.40 ? 147 GLU A CB 1 ATOM 952 C CG . GLU A 1 127 ? -36.560 -16.262 83.210 1.00 26.38 ? 147 GLU A CG 1 ATOM 953 C CD . GLU A 1 127 ? -36.997 -17.346 82.239 1.00 26.12 ? 147 GLU A CD 1 ATOM 954 O OE1 . GLU A 1 127 ? -37.557 -17.014 81.170 1.00 25.68 ? 147 GLU A OE1 1 ATOM 955 O OE2 . GLU A 1 127 ? -36.775 -18.537 82.547 1.00 25.06 ? 147 GLU A OE2 1 ATOM 956 N N . TYR A 1 128 ? -35.002 -12.540 83.278 1.00 26.01 ? 148 TYR A N 1 ATOM 957 C CA . TYR A 1 128 ? -33.621 -12.070 83.359 1.00 26.08 ? 148 TYR A CA 1 ATOM 958 C C . TYR A 1 128 ? -33.319 -11.434 84.720 1.00 26.40 ? 148 TYR A C 1 ATOM 959 O O . TYR A 1 128 ? -32.251 -11.680 85.300 1.00 26.35 ? 148 TYR A O 1 ATOM 960 C CB . TYR A 1 128 ? -33.306 -11.060 82.247 1.00 25.90 ? 148 TYR A CB 1 ATOM 961 C CG . TYR A 1 128 ? -32.883 -11.675 80.934 1.00 25.48 ? 148 TYR A CG 1 ATOM 962 C CD1 . TYR A 1 128 ? -31.700 -12.410 80.837 1.00 26.43 ? 148 TYR A CD1 1 ATOM 963 C CD2 . TYR A 1 128 ? -33.634 -11.489 79.778 1.00 25.42 ? 148 TYR A CD2 1 ATOM 964 C CE1 . TYR A 1 128 ? -31.295 -12.966 79.637 1.00 25.37 ? 148 TYR A CE1 1 ATOM 965 C CE2 . TYR A 1 128 ? -33.231 -12.034 78.567 1.00 24.73 ? 148 TYR A CE2 1 ATOM 966 C CZ . TYR A 1 128 ? -32.055 -12.766 78.508 1.00 24.94 ? 148 TYR A CZ 1 ATOM 967 O OH . TYR A 1 128 ? -31.653 -13.312 77.325 1.00 23.51 ? 148 TYR A OH 1 ATOM 968 N N . ALA A 1 129 ? -34.242 -10.605 85.210 1.00 26.54 ? 149 ALA A N 1 ATOM 969 C CA . ALA A 1 129 ? -34.077 -9.957 86.517 1.00 27.23 ? 149 ALA A CA 1 ATOM 970 C C . ALA A 1 129 ? -33.892 -11.011 87.608 1.00 27.57 ? 149 ALA A C 1 ATOM 971 O O . ALA A 1 129 ? -32.973 -10.916 88.415 1.00 27.97 ? 149 ALA A O 1 ATOM 972 C CB . ALA A 1 129 ? -35.271 -9.061 86.840 1.00 26.71 ? 149 ALA A CB 1 ATOM 973 N N . LEU A 1 130 ? -34.756 -12.022 87.611 1.00 27.83 ? 150 LEU A N 1 ATOM 974 C CA . LEU A 1 130 ? -34.640 -13.114 88.576 1.00 27.88 ? 150 LEU A CA 1 ATOM 975 C C . LEU A 1 130 ? -33.336 -13.900 88.383 1.00 28.33 ? 150 LEU A C 1 ATOM 976 O O . LEU A 1 130 ? -32.728 -14.340 89.356 1.00 28.25 ? 150 LEU A O 1 ATOM 977 C CB . LEU A 1 130 ? -35.844 -14.041 88.484 1.00 27.58 ? 150 LEU A CB 1 ATOM 978 C CG . LEU A 1 130 ? -37.194 -13.437 88.883 1.00 26.71 ? 150 LEU A CG 1 ATOM 979 C CD1 . LEU A 1 130 ? -38.323 -14.325 88.419 1.00 25.95 ? 150 LEU A CD1 1 ATOM 980 C CD2 . LEU A 1 130 ? -37.282 -13.213 90.394 1.00 25.53 ? 150 LEU A CD2 1 ATOM 981 N N . LEU A 1 131 ? -32.895 -14.067 87.138 1.00 28.75 ? 151 LEU A N 1 ATOM 982 C CA . LEU A 1 131 ? -31.618 -14.746 86.890 1.00 29.02 ? 151 LEU A CA 1 ATOM 983 C C . LEU A 1 131 ? -30.477 -13.959 87.511 1.00 29.45 ? 151 LEU A C 1 ATOM 984 O O . LEU A 1 131 ? -29.584 -14.532 88.147 1.00 29.46 ? 151 LEU A O 1 ATOM 985 C CB . LEU A 1 131 ? -31.346 -14.934 85.390 1.00 28.98 ? 151 LEU A CB 1 ATOM 986 C CG . LEU A 1 131 ? -31.968 -16.139 84.687 1.00 28.72 ? 151 LEU A CG 1 ATOM 987 C CD1 . LEU A 1 131 ? -31.712 -16.060 83.182 1.00 29.06 ? 151 LEU A CD1 1 ATOM 988 C CD2 . LEU A 1 131 ? -31.407 -17.434 85.251 1.00 27.42 ? 151 LEU A CD2 1 ATOM 989 N N . TYR A 1 132 ? -30.503 -12.644 87.326 1.00 29.86 ? 152 TYR A N 1 ATOM 990 C CA . TYR A 1 132 ? -29.465 -11.809 87.886 1.00 30.31 ? 152 TYR A CA 1 ATOM 991 C C . TYR A 1 132 ? -29.481 -11.917 89.422 1.00 30.63 ? 152 TYR A C 1 ATOM 992 O O . TYR A 1 132 ? -28.427 -11.962 90.051 1.00 30.36 ? 152 TYR A O 1 ATOM 993 C CB . TYR A 1 132 ? -29.593 -10.354 87.410 1.00 30.42 ? 152 TYR A CB 1 ATOM 994 C CG . TYR A 1 132 ? -28.249 -9.679 87.181 1.00 30.64 ? 152 TYR A CG 1 ATOM 995 N N . HIS A 1 133 ? -30.672 -11.992 90.011 1.00 31.00 ? 153 HIS A N 1 ATOM 996 C CA . HIS A 1 133 ? -30.804 -12.180 91.463 1.00 31.40 ? 153 HIS A CA 1 ATOM 997 C C . HIS A 1 133 ? -30.219 -13.519 91.901 1.00 31.61 ? 153 HIS A C 1 ATOM 998 O O . HIS A 1 133 ? -29.489 -13.586 92.901 1.00 31.67 ? 153 HIS A O 1 ATOM 999 C CB . HIS A 1 133 ? -32.270 -12.089 91.899 1.00 31.46 ? 153 HIS A CB 1 ATOM 1000 C CG . HIS A 1 133 ? -32.490 -12.382 93.352 0.50 31.17 ? 153 HIS A CG 1 ATOM 1001 N ND1 . HIS A 1 133 ? -32.593 -11.390 94.303 0.50 31.63 ? 153 HIS A ND1 1 ATOM 1002 C CD2 . HIS A 1 133 ? -32.636 -13.553 94.014 0.50 31.00 ? 153 HIS A CD2 1 ATOM 1003 C CE1 . HIS A 1 133 ? -32.791 -11.938 95.488 0.50 31.43 ? 153 HIS A CE1 1 ATOM 1004 N NE2 . HIS A 1 133 ? -32.818 -13.250 95.341 0.50 31.17 ? 153 HIS A NE2 1 ATOM 1005 N N . THR A 1 134 ? -30.542 -14.573 91.147 1.00 31.71 ? 154 THR A N 1 ATOM 1006 C CA . THR A 1 134 ? -30.014 -15.910 91.401 1.00 31.79 ? 154 THR A CA 1 ATOM 1007 C C . THR A 1 134 ? -28.484 -15.906 91.358 1.00 31.92 ? 154 THR A C 1 ATOM 1008 O O . THR A 1 134 ? -27.836 -16.482 92.233 1.00 31.74 ? 154 THR A O 1 ATOM 1009 C CB . THR A 1 134 ? -30.548 -16.943 90.384 1.00 31.77 ? 154 THR A CB 1 ATOM 1010 O OG1 . THR A 1 134 ? -31.982 -16.929 90.374 1.00 31.87 ? 154 THR A OG1 1 ATOM 1011 C CG2 . THR A 1 134 ? -30.075 -18.343 90.738 1.00 32.14 ? 154 THR A CG2 1 ATOM 1012 N N . LEU A 1 135 ? -27.911 -15.236 90.363 1.00 32.15 ? 155 LEU A N 1 ATOM 1013 C CA . LEU A 1 135 ? -26.452 -15.189 90.222 1.00 32.41 ? 155 LEU A CA 1 ATOM 1014 C C . LEU A 1 135 ? -25.786 -14.413 91.355 1.00 32.73 ? 155 LEU A C 1 ATOM 1015 O O . LEU A 1 135 ? -24.736 -14.824 91.849 1.00 32.56 ? 155 LEU A O 1 ATOM 1016 C CB . LEU A 1 135 ? -26.043 -14.573 88.881 1.00 32.60 ? 155 LEU A CB 1 ATOM 1017 C CG . LEU A 1 135 ? -26.186 -15.435 87.620 1.00 32.87 ? 155 LEU A CG 1 ATOM 1018 C CD1 . LEU A 1 135 ? -25.549 -14.724 86.438 1.00 33.23 ? 155 LEU A CD1 1 ATOM 1019 C CD2 . LEU A 1 135 ? -25.559 -16.792 87.801 1.00 32.65 ? 155 LEU A CD2 1 ATOM 1020 N N . GLN A 1 136 ? -26.388 -13.286 91.743 1.00 33.01 ? 156 GLN A N 1 ATOM 1021 C CA . GLN A 1 136 ? -25.866 -12.447 92.826 1.00 33.57 ? 156 GLN A CA 1 ATOM 1022 C C . GLN A 1 136 ? -25.762 -13.218 94.144 1.00 33.62 ? 156 GLN A C 1 ATOM 1023 O O . GLN A 1 136 ? -24.761 -13.100 94.850 1.00 34.01 ? 156 GLN A O 1 ATOM 1024 C CB . GLN A 1 136 ? -26.736 -11.194 93.010 1.00 34.04 ? 156 GLN A CB 1 ATOM 1025 C CG . GLN A 1 136 ? -26.508 -10.125 91.936 1.00 35.32 ? 156 GLN A CG 1 ATOM 1026 C CD . GLN A 1 136 ? -27.419 -8.927 92.092 1.00 37.97 ? 156 GLN A CD 1 ATOM 1027 O OE1 . GLN A 1 136 ? -28.645 -9.061 92.144 1.00 38.86 ? 156 GLN A OE1 1 ATOM 1028 N NE2 . GLN A 1 136 ? -26.823 -7.740 92.163 1.00 39.39 ? 156 GLN A NE2 1 ATOM 1029 N N . GLU A 1 137 ? -26.784 -14.016 94.454 1.00 33.29 ? 157 GLU A N 1 ATOM 1030 C CA . GLU A 1 137 ? -26.772 -14.882 95.635 1.00 33.40 ? 157 GLU A CA 1 ATOM 1031 C C . GLU A 1 137 ? -25.828 -16.073 95.451 1.00 32.71 ? 157 GLU A C 1 ATOM 1032 O O . GLU A 1 137 ? -24.929 -16.295 96.263 1.00 32.56 ? 157 GLU A O 1 ATOM 1033 C CB . GLU A 1 137 ? -28.180 -15.403 95.937 1.00 33.80 ? 157 GLU A CB 1 ATOM 1034 C CG . GLU A 1 137 ? -29.182 -14.326 96.360 1.00 35.91 ? 157 GLU A CG 1 ATOM 1035 C CD . GLU A 1 137 ? -29.047 -13.896 97.821 1.00 38.87 ? 157 GLU A CD 1 ATOM 1036 O OE1 . GLU A 1 137 ? -28.106 -14.337 98.523 1.00 40.46 ? 157 GLU A OE1 1 ATOM 1037 O OE2 . GLU A 1 137 ? -29.902 -13.103 98.268 1.00 41.93 ? 157 GLU A OE2 1 ATOM 1038 N N . ALA A 1 138 ? -26.033 -16.834 94.376 1.00 31.94 ? 158 ALA A N 1 ATOM 1039 C CA . ALA A 1 138 ? -25.288 -18.072 94.163 1.00 31.24 ? 158 ALA A CA 1 ATOM 1040 C C . ALA A 1 138 ? -23.780 -17.845 94.040 1.00 30.80 ? 158 ALA A C 1 ATOM 1041 O O . ALA A 1 138 ? -23.001 -18.699 94.438 1.00 30.49 ? 158 ALA A O 1 ATOM 1042 C CB . ALA A 1 138 ? -25.822 -18.824 92.947 1.00 30.85 ? 158 ALA A CB 1 ATOM 1043 N N . THR A 1 139 ? -23.368 -16.694 93.517 1.00 30.67 ? 159 THR A N 1 ATOM 1044 C CA . THR A 1 139 ? -21.948 -16.439 93.268 1.00 30.58 ? 159 THR A CA 1 ATOM 1045 C C . THR A 1 139 ? -21.239 -15.687 94.407 1.00 30.46 ? 159 THR A C 1 ATOM 1046 O O . THR A 1 139 ? -20.069 -15.334 94.277 1.00 29.65 ? 159 THR A O 1 ATOM 1047 C CB . THR A 1 139 ? -21.731 -15.688 91.927 1.00 30.82 ? 159 THR A CB 1 ATOM 1048 O OG1 . THR A 1 139 ? -22.315 -14.380 91.991 1.00 31.05 ? 159 THR A OG1 1 ATOM 1049 C CG2 . THR A 1 139 ? -22.335 -16.467 90.757 1.00 30.55 ? 159 THR A CG2 1 ATOM 1050 N N . LYS A 1 140 ? -21.928 -15.477 95.527 1.00 30.68 ? 160 LYS A N 1 ATOM 1051 C CA . LYS A 1 140 ? -21.321 -14.818 96.701 1.00 31.08 ? 160 LYS A CA 1 ATOM 1052 C C . LYS A 1 140 ? -19.977 -15.415 97.142 1.00 30.50 ? 160 LYS A C 1 ATOM 1053 O O . LYS A 1 140 ? -19.032 -14.674 97.411 1.00 30.82 ? 160 LYS A O 1 ATOM 1054 C CB . LYS A 1 140 ? -22.293 -14.790 97.886 1.00 31.61 ? 160 LYS A CB 1 ATOM 1055 C CG . LYS A 1 140 ? -23.395 -13.758 97.739 1.00 33.40 ? 160 LYS A CG 1 ATOM 1056 C CD . LYS A 1 140 ? -24.128 -13.504 99.050 1.00 35.42 ? 160 LYS A CD 1 ATOM 1057 C CE . LYS A 1 140 ? -25.236 -12.476 98.870 1.00 36.31 ? 160 LYS A CE 1 ATOM 1058 N NZ . LYS A 1 140 ? -24.734 -11.210 98.248 1.00 38.22 ? 160 LYS A NZ 1 ATOM 1059 N N . PRO A 1 141 ? -19.866 -16.749 97.187 1.00 29.82 ? 161 PRO A N 1 ATOM 1060 C CA . PRO A 1 141 ? -18.553 -17.320 97.502 1.00 29.47 ? 161 PRO A CA 1 ATOM 1061 C C . PRO A 1 141 ? -17.430 -16.855 96.566 1.00 29.30 ? 161 PRO A C 1 ATOM 1062 O O . PRO A 1 141 ? -16.254 -16.828 96.968 1.00 28.84 ? 161 PRO A O 1 ATOM 1063 C CB . PRO A 1 141 ? -18.774 -18.828 97.351 1.00 29.53 ? 161 PRO A CB 1 ATOM 1064 C CG . PRO A 1 141 ? -20.230 -19.031 97.489 1.00 29.33 ? 161 PRO A CG 1 ATOM 1065 C CD . PRO A 1 141 ? -20.893 -17.786 96.998 1.00 30.16 ? 161 PRO A CD 1 ATOM 1066 N N . LEU A 1 142 ? -17.784 -16.485 95.335 1.00 28.89 ? 162 LEU A N 1 ATOM 1067 C CA . LEU A 1 142 ? -16.781 -16.093 94.339 1.00 28.73 ? 162 LEU A CA 1 ATOM 1068 C C . LEU A 1 142 ? -16.475 -14.587 94.312 1.00 28.69 ? 162 LEU A C 1 ATOM 1069 O O . LEU A 1 142 ? -15.692 -14.121 93.485 1.00 28.19 ? 162 LEU A O 1 ATOM 1070 C CB . LEU A 1 142 ? -17.218 -16.564 92.942 1.00 28.40 ? 162 LEU A CB 1 ATOM 1071 C CG . LEU A 1 142 ? -17.271 -18.072 92.710 1.00 28.12 ? 162 LEU A CG 1 ATOM 1072 C CD1 . LEU A 1 142 ? -17.902 -18.365 91.362 1.00 26.40 ? 162 LEU A CD1 1 ATOM 1073 C CD2 . LEU A 1 142 ? -15.881 -18.713 92.814 1.00 27.87 ? 162 LEU A CD2 1 ATOM 1074 N N . HIS A 1 143 ? -17.075 -13.821 95.215 1.00 29.10 ? 163 HIS A N 1 ATOM 1075 C CA . HIS A 1 143 ? -16.942 -12.365 95.161 1.00 29.43 ? 163 HIS A CA 1 ATOM 1076 C C . HIS A 1 143 ? -15.474 -11.924 95.118 1.00 29.33 ? 163 HIS A C 1 ATOM 1077 O O . HIS A 1 143 ? -15.049 -11.197 94.218 1.00 28.87 ? 163 HIS A O 1 ATOM 1078 C CB . HIS A 1 143 ? -17.657 -11.733 96.352 1.00 29.74 ? 163 HIS A CB 1 ATOM 1079 C CG . HIS A 1 143 ? -17.530 -10.244 96.415 1.00 31.47 ? 163 HIS A CG 1 ATOM 1080 N ND1 . HIS A 1 143 ? -18.213 -9.402 95.564 1.00 32.71 ? 163 HIS A ND1 1 ATOM 1081 C CD2 . HIS A 1 143 ? -16.817 -9.445 97.245 1.00 33.03 ? 163 HIS A CD2 1 ATOM 1082 C CE1 . HIS A 1 143 ? -17.923 -8.149 95.862 1.00 33.29 ? 163 HIS A CE1 1 ATOM 1083 N NE2 . HIS A 1 143 ? -17.077 -8.146 96.877 1.00 33.86 ? 163 HIS A NE2 1 ATOM 1084 N N . GLN A 1 144 ? -14.690 -12.391 96.075 1.00 29.33 ? 164 GLN A N 1 ATOM 1085 C CA . GLN A 1 144 ? -13.292 -11.986 96.154 1.00 29.62 ? 164 GLN A CA 1 ATOM 1086 C C . GLN A 1 144 ? -12.510 -12.505 94.951 1.00 28.93 ? 164 GLN A C 1 ATOM 1087 O O . GLN A 1 144 ? -11.626 -11.827 94.439 1.00 28.65 ? 164 GLN A O 1 ATOM 1088 C CB . GLN A 1 144 ? -12.663 -12.491 97.452 1.00 29.99 ? 164 GLN A CB 1 ATOM 1089 C CG . GLN A 1 144 ? -11.396 -11.772 97.820 1.00 32.77 ? 164 GLN A CG 1 ATOM 1090 C CD . GLN A 1 144 ? -11.629 -10.289 98.009 1.00 35.42 ? 164 GLN A CD 1 ATOM 1091 O OE1 . GLN A 1 144 ? -12.437 -9.884 98.847 1.00 38.76 ? 164 GLN A OE1 1 ATOM 1092 N NE2 . GLN A 1 144 ? -10.944 -9.471 97.212 1.00 36.53 ? 164 GLN A NE2 1 ATOM 1093 N N . PHE A 1 145 ? -12.838 -13.718 94.519 1.00 28.58 ? 165 PHE A N 1 ATOM 1094 C CA . PHE A 1 145 ? -12.326 -14.261 93.256 1.00 28.46 ? 165 PHE A CA 1 ATOM 1095 C C . PHE A 1 145 ? -12.609 -13.291 92.101 1.00 28.55 ? 165 PHE A C 1 ATOM 1096 O O . PHE A 1 145 ? -11.713 -12.989 91.303 1.00 28.58 ? 165 PHE A O 1 ATOM 1097 C CB . PHE A 1 145 ? -12.951 -15.634 92.983 1.00 28.21 ? 165 PHE A CB 1 ATOM 1098 C CG . PHE A 1 145 ? -12.685 -16.180 91.597 1.00 27.84 ? 165 PHE A CG 1 ATOM 1099 C CD1 . PHE A 1 145 ? -11.473 -16.777 91.288 1.00 27.66 ? 165 PHE A CD1 1 ATOM 1100 C CD2 . PHE A 1 145 ? -13.669 -16.131 90.615 1.00 27.47 ? 165 PHE A CD2 1 ATOM 1101 C CE1 . PHE A 1 145 ? -11.236 -17.295 90.013 1.00 27.80 ? 165 PHE A CE1 1 ATOM 1102 C CE2 . PHE A 1 145 ? -13.441 -16.651 89.348 1.00 26.38 ? 165 PHE A CE2 1 ATOM 1103 C CZ . PHE A 1 145 ? -12.226 -17.233 89.049 1.00 26.81 ? 165 PHE A CZ 1 ATOM 1104 N N . PHE A 1 146 ? -13.843 -12.794 92.024 1.00 28.74 ? 166 PHE A N 1 ATOM 1105 C CA . PHE A 1 146 ? -14.216 -11.858 90.961 1.00 29.06 ? 166 PHE A CA 1 ATOM 1106 C C . PHE A 1 146 ? -13.342 -10.604 90.986 1.00 29.62 ? 166 PHE A C 1 ATOM 1107 O O . PHE A 1 146 ? -12.799 -10.187 89.958 1.00 29.81 ? 166 PHE A O 1 ATOM 1108 C CB . PHE A 1 146 ? -15.695 -11.445 91.061 1.00 28.94 ? 166 PHE A CB 1 ATOM 1109 C CG . PHE A 1 146 ? -16.681 -12.548 90.758 1.00 27.89 ? 166 PHE A CG 1 ATOM 1110 C CD1 . PHE A 1 146 ? -16.418 -13.522 89.792 1.00 28.12 ? 166 PHE A CD1 1 ATOM 1111 C CD2 . PHE A 1 146 ? -17.900 -12.581 91.410 1.00 27.34 ? 166 PHE A CD2 1 ATOM 1112 C CE1 . PHE A 1 146 ? -17.345 -14.527 89.518 1.00 27.86 ? 166 PHE A CE1 1 ATOM 1113 C CE2 . PHE A 1 146 ? -18.832 -13.583 91.139 1.00 28.21 ? 166 PHE A CE2 1 ATOM 1114 C CZ . PHE A 1 146 ? -18.555 -14.552 90.186 1.00 27.27 ? 166 PHE A CZ 1 ATOM 1115 N N . LEU A 1 147 ? -13.204 -10.008 92.165 1.00 30.40 ? 167 LEU A N 1 ATOM 1116 C CA . LEU A 1 147 ? -12.445 -8.773 92.302 1.00 30.85 ? 167 LEU A CA 1 ATOM 1117 C C . LEU A 1 147 ? -10.980 -8.996 91.933 1.00 31.34 ? 167 LEU A C 1 ATOM 1118 O O . LEU A 1 147 ? -10.405 -8.205 91.185 1.00 31.39 ? 167 LEU A O 1 ATOM 1119 C CB . LEU A 1 147 ? -12.562 -8.210 93.721 1.00 31.04 ? 167 LEU A CB 1 ATOM 1120 C CG . LEU A 1 147 ? -13.915 -7.621 94.125 1.00 31.00 ? 167 LEU A CG 1 ATOM 1121 C CD1 . LEU A 1 147 ? -13.837 -7.145 95.576 1.00 31.30 ? 167 LEU A CD1 1 ATOM 1122 C CD2 . LEU A 1 147 ? -14.342 -6.471 93.208 1.00 30.52 ? 167 LEU A CD2 1 ATOM 1123 N N . ASN A 1 148 ? -10.390 -10.080 92.433 1.00 31.74 ? 168 ASN A N 1 ATOM 1124 C CA . ASN A 1 148 ? -8.984 -10.380 92.144 1.00 32.11 ? 168 ASN A CA 1 ATOM 1125 C C . ASN A 1 148 ? -8.730 -10.686 90.668 1.00 31.76 ? 168 ASN A C 1 ATOM 1126 O O . ASN A 1 148 ? -7.733 -10.239 90.116 1.00 31.91 ? 168 ASN A O 1 ATOM 1127 C CB . ASN A 1 148 ? -8.480 -11.548 92.994 1.00 32.59 ? 168 ASN A CB 1 ATOM 1128 C CG . ASN A 1 148 ? -8.490 -11.241 94.482 1.00 33.86 ? 168 ASN A CG 1 ATOM 1129 O OD1 . ASN A 1 148 ? -8.914 -10.167 94.905 1.00 36.95 ? 168 ASN A OD1 1 ATOM 1130 N ND2 . ASN A 1 148 ? -8.030 -12.194 95.286 1.00 35.72 ? 168 ASN A ND2 1 ATOM 1131 N N . THR A 1 149 ? -9.621 -11.442 90.027 1.00 31.31 ? 169 THR A N 1 ATOM 1132 C CA . THR A 1 149 ? -9.399 -11.846 88.626 1.00 30.96 ? 169 THR A CA 1 ATOM 1133 C C . THR A 1 149 ? -9.860 -10.810 87.582 1.00 30.64 ? 169 THR A C 1 ATOM 1134 O O . THR A 1 149 ? -9.304 -10.753 86.480 1.00 30.51 ? 169 THR A O 1 ATOM 1135 C CB . THR A 1 149 ? -10.057 -13.210 88.309 1.00 30.96 ? 169 THR A CB 1 ATOM 1136 O OG1 . THR A 1 149 ? -11.460 -13.148 88.583 1.00 31.07 ? 169 THR A OG1 1 ATOM 1137 C CG2 . THR A 1 149 ? -9.415 -14.329 89.137 1.00 30.64 ? 169 THR A CG2 1 ATOM 1138 N N . THR A 1 150 ? -10.859 -9.995 87.920 1.00 30.14 ? 170 THR A N 1 ATOM 1139 C CA . THR A 1 150 ? -11.473 -9.084 86.935 1.00 29.85 ? 170 THR A CA 1 ATOM 1140 C C . THR A 1 150 ? -11.574 -7.614 87.344 1.00 29.52 ? 170 THR A C 1 ATOM 1141 O O . THR A 1 150 ? -11.745 -6.758 86.487 1.00 29.56 ? 170 THR A O 1 ATOM 1142 C CB . THR A 1 150 ? -12.896 -9.547 86.598 1.00 29.72 ? 170 THR A CB 1 ATOM 1143 O OG1 . THR A 1 150 ? -13.746 -9.355 87.734 1.00 29.01 ? 170 THR A OG1 1 ATOM 1144 C CG2 . THR A 1 150 ? -12.898 -11.020 86.200 1.00 29.44 ? 170 THR A CG2 1 ATOM 1145 N N . GLY A 1 151 ? -11.501 -7.319 88.640 1.00 29.16 ? 171 GLY A N 1 ATOM 1146 C CA . GLY A 1 151 ? -11.791 -5.973 89.134 1.00 28.72 ? 171 GLY A CA 1 ATOM 1147 C C . GLY A 1 151 ? -13.269 -5.593 89.092 1.00 28.64 ? 171 GLY A C 1 ATOM 1148 O O . GLY A 1 151 ? -13.628 -4.473 89.460 1.00 28.84 ? 171 GLY A O 1 ATOM 1149 N N . PHE A 1 152 ? -14.130 -6.507 88.638 1.00 28.07 ? 172 PHE A N 1 ATOM 1150 C CA . PHE A 1 152 ? -15.574 -6.261 88.539 1.00 27.62 ? 172 PHE A CA 1 ATOM 1151 C C . PHE A 1 152 ? -16.272 -7.272 89.455 1.00 27.30 ? 172 PHE A C 1 ATOM 1152 O O . PHE A 1 152 ? -15.638 -8.220 89.919 1.00 27.09 ? 172 PHE A O 1 ATOM 1153 C CB . PHE A 1 152 ? -16.074 -6.457 87.094 1.00 27.27 ? 172 PHE A CB 1 ATOM 1154 C CG . PHE A 1 152 ? -15.695 -5.343 86.120 1.00 27.00 ? 172 PHE A CG 1 ATOM 1155 C CD1 . PHE A 1 152 ? -14.385 -4.893 85.994 1.00 26.07 ? 172 PHE A CD1 1 ATOM 1156 C CD2 . PHE A 1 152 ? -16.653 -4.803 85.273 1.00 25.59 ? 172 PHE A CD2 1 ATOM 1157 C CE1 . PHE A 1 152 ? -14.048 -3.897 85.078 1.00 25.12 ? 172 PHE A CE1 1 ATOM 1158 C CE2 . PHE A 1 152 ? -16.324 -3.812 84.360 1.00 25.79 ? 172 PHE A CE2 1 ATOM 1159 C CZ . PHE A 1 152 ? -15.020 -3.357 84.264 1.00 25.40 ? 172 PHE A CZ 1 ATOM 1160 N N . SER A 1 153 ? -17.572 -7.093 89.680 1.00 27.01 ? 173 SER A N 1 ATOM 1161 C CA . SER A 1 153 ? -18.335 -7.968 90.582 1.00 27.44 ? 173 SER A CA 1 ATOM 1162 C C . SER A 1 153 ? -19.822 -8.028 90.232 1.00 27.77 ? 173 SER A C 1 ATOM 1163 O O . SER A 1 153 ? -20.304 -7.244 89.411 1.00 26.97 ? 173 SER A O 1 ATOM 1164 C CB . SER A 1 153 ? -18.192 -7.468 92.027 1.00 27.87 ? 173 SER A CB 1 ATOM 1165 O OG . SER A 1 153 ? -18.704 -6.143 92.170 1.00 27.83 ? 173 SER A OG 1 ATOM 1166 N N . PHE A 1 154 ? -20.538 -8.957 90.870 1.00 28.41 ? 174 PHE A N 1 ATOM 1167 C CA . PHE A 1 154 ? -22.001 -9.013 90.799 1.00 28.98 ? 174 PHE A CA 1 ATOM 1168 C C . PHE A 1 154 ? -22.657 -8.301 91.989 1.00 29.86 ? 174 PHE A C 1 ATOM 1169 O O . PHE A 1 154 ? -23.758 -7.770 91.847 1.00 30.08 ? 174 PHE A O 1 ATOM 1170 C CB . PHE A 1 154 ? -22.521 -10.463 90.738 1.00 29.17 ? 174 PHE A CB 1 ATOM 1171 C CG . PHE A 1 154 ? -22.532 -11.064 89.353 1.00 29.16 ? 174 PHE A CG 1 ATOM 1172 C CD1 . PHE A 1 154 ? -23.327 -10.522 88.349 1.00 29.87 ? 174 PHE A CD1 1 ATOM 1173 C CD2 . PHE A 1 154 ? -21.771 -12.186 89.062 1.00 29.64 ? 174 PHE A CD2 1 ATOM 1174 C CE1 . PHE A 1 154 ? -23.342 -11.074 87.070 1.00 30.22 ? 174 PHE A CE1 1 ATOM 1175 C CE2 . PHE A 1 154 ? -21.774 -12.748 87.780 1.00 30.35 ? 174 PHE A CE2 1 ATOM 1176 C CZ . PHE A 1 154 ? -22.563 -12.195 86.787 1.00 30.75 ? 174 PHE A CZ 1 ATOM 1177 N N . GLN A 1 155 ? -22.017 -8.311 93.163 1.00 30.76 ? 175 GLN A N 1 ATOM 1178 C CA . GLN A 1 155 ? -22.604 -7.659 94.350 1.00 31.34 ? 175 GLN A CA 1 ATOM 1179 C C . GLN A 1 155 ? -21.964 -6.300 94.609 1.00 31.35 ? 175 GLN A C 1 ATOM 1180 O O . GLN A 1 155 ? -20.756 -6.134 94.407 1.00 31.30 ? 175 GLN A O 1 ATOM 1181 C CB . GLN A 1 155 ? -22.545 -8.558 95.600 1.00 31.75 ? 175 GLN A CB 1 ATOM 1182 C CG . GLN A 1 155 ? -21.189 -8.722 96.264 1.00 33.73 ? 175 GLN A CG 1 ATOM 1183 C CD . GLN A 1 155 ? -21.287 -9.346 97.671 1.00 36.29 ? 175 GLN A CD 1 ATOM 1184 O OE1 . GLN A 1 155 ? -22.291 -9.982 98.026 1.00 37.35 ? 175 GLN A OE1 1 ATOM 1185 N NE2 . GLN A 1 155 ? -20.234 -9.174 98.464 1.00 35.51 ? 175 GLN A NE2 1 ATOM 1186 N N . ASP A 1 156 ? -22.791 -5.332 95.019 1.00 31.26 ? 176 ASP A N 1 ATOM 1187 C CA . ASP A 1 156 ? -22.347 -3.960 95.343 1.00 31.31 ? 176 ASP A CA 1 ATOM 1188 C C . ASP A 1 156 ? -21.559 -3.285 94.208 1.00 31.22 ? 176 ASP A C 1 ATOM 1189 O O . ASP A 1 156 ? -20.551 -2.633 94.467 1.00 31.03 ? 176 ASP A O 1 ATOM 1190 C CB . ASP A 1 156 ? -21.470 -3.956 96.607 1.00 31.34 ? 176 ASP A CB 1 ATOM 1191 C CG . ASP A 1 156 ? -22.140 -4.611 97.805 1.00 31.54 ? 176 ASP A CG 1 ATOM 1192 O OD1 . ASP A 1 156 ? -23.366 -4.468 97.987 1.00 32.55 ? 176 ASP A OD1 1 ATOM 1193 O OD2 . ASP A 1 156 ? -21.417 -5.255 98.585 1.00 32.43 ? 176 ASP A OD2 1 ATOM 1194 N N . CYS A 1 157 ? -21.995 -3.460 92.960 1.00 31.04 ? 177 CYS A N 1 ATOM 1195 C CA . CYS A 1 157 ? -21.302 -2.859 91.822 1.00 31.04 ? 177 CYS A CA 1 ATOM 1196 C C . CYS A 1 157 ? -22.072 -1.651 91.327 1.00 31.13 ? 177 CYS A C 1 ATOM 1197 O O . CYS A 1 157 ? -23.282 -1.533 91.559 1.00 30.88 ? 177 CYS A O 1 ATOM 1198 C CB . CYS A 1 157 ? -21.123 -3.861 90.668 1.00 31.22 ? 177 CYS A CB 1 ATOM 1199 S SG . CYS A 1 157 ? -22.653 -4.285 89.772 1.00 30.65 ? 177 CYS A SG 1 ATOM 1200 N N . HIS A 1 158 ? -21.367 -0.759 90.637 1.00 31.02 ? 178 HIS A N 1 ATOM 1201 C CA . HIS A 1 158 ? -21.990 0.436 90.077 1.00 31.20 ? 178 HIS A CA 1 ATOM 1202 C C . HIS A 1 158 ? -21.545 0.644 88.631 1.00 31.14 ? 178 HIS A C 1 ATOM 1203 O O . HIS A 1 158 ? -22.368 0.558 87.722 1.00 31.75 ? 178 HIS A O 1 ATOM 1204 C CB . HIS A 1 158 ? -21.692 1.658 90.962 1.00 31.15 ? 178 HIS A CB 1 ATOM 1205 C CG . HIS A 1 158 ? -22.105 1.470 92.393 1.00 31.82 ? 178 HIS A CG 1 ATOM 1206 N ND1 . HIS A 1 158 ? -23.253 2.026 92.917 1.00 32.04 ? 178 HIS A ND1 1 ATOM 1207 C CD2 . HIS A 1 158 ? -21.543 0.753 93.396 1.00 30.88 ? 178 HIS A CD2 1 ATOM 1208 C CE1 . HIS A 1 158 ? -23.372 1.670 94.184 1.00 32.13 ? 178 HIS A CE1 1 ATOM 1209 N NE2 . HIS A 1 158 ? -22.349 0.893 94.498 1.00 32.40 ? 178 HIS A NE2 1 ATOM 1210 N N . ASP A 1 159 ? -20.256 0.915 88.428 1.00 30.87 ? 179 ASP A N 1 ATOM 1211 C CA . ASP A 1 159 ? -19.670 1.076 87.098 1.00 30.73 ? 179 ASP A CA 1 ATOM 1212 C C . ASP A 1 159 ? -18.735 -0.086 86.750 1.00 30.04 ? 179 ASP A C 1 ATOM 1213 O O . ASP A 1 159 ? -18.177 -0.114 85.659 1.00 29.61 ? 179 ASP A O 1 ATOM 1214 C CB . ASP A 1 159 ? -18.885 2.396 87.009 1.00 31.06 ? 179 ASP A CB 1 ATOM 1215 C CG . ASP A 1 159 ? -19.773 3.637 87.151 1.00 32.95 ? 179 ASP A CG 1 ATOM 1216 O OD1 . ASP A 1 159 ? -20.929 3.643 86.672 1.00 35.31 ? 179 ASP A OD1 1 ATOM 1217 O OD2 . ASP A 1 159 ? -19.300 4.631 87.743 1.00 36.87 ? 179 ASP A OD2 1 ATOM 1218 N N . ARG A 1 160 ? -18.567 -1.043 87.666 1.00 29.39 ? 180 ARG A N 1 ATOM 1219 C CA . ARG A 1 160 ? -17.718 -2.212 87.422 1.00 29.21 ? 180 ARG A CA 1 ATOM 1220 C C . ARG A 1 160 ? -18.514 -3.492 87.682 1.00 28.52 ? 180 ARG A C 1 ATOM 1221 O O . ARG A 1 160 ? -18.176 -4.307 88.555 1.00 28.02 ? 180 ARG A O 1 ATOM 1222 C CB . ARG A 1 160 ? -16.441 -2.149 88.274 1.00 29.51 ? 180 ARG A CB 1 ATOM 1223 C CG . ARG A 1 160 ? -15.641 -0.863 88.063 1.00 31.42 ? 180 ARG A CG 1 ATOM 1224 C CD . ARG A 1 160 ? -14.384 -0.818 88.916 1.00 34.22 ? 180 ARG A CD 1 ATOM 1225 N NE . ARG A 1 160 ? -13.293 -1.564 88.295 1.00 37.38 ? 180 ARG A NE 1 ATOM 1226 C CZ . ARG A 1 160 ? -12.448 -1.077 87.382 1.00 39.21 ? 180 ARG A CZ 1 ATOM 1227 N NH1 . ARG A 1 160 ? -12.525 0.185 86.962 1.00 38.66 ? 180 ARG A NH1 1 ATOM 1228 N NH2 . ARG A 1 160 ? -11.504 -1.871 86.884 1.00 40.59 ? 180 ARG A NH2 1 ATOM 1229 N N . CYS A 1 161 ? -19.580 -3.653 86.904 1.00 27.75 ? 181 CYS A N 1 ATOM 1230 C CA . CYS A 1 161 ? -20.483 -4.787 87.058 1.00 27.24 ? 181 CYS A CA 1 ATOM 1231 C C . CYS A 1 161 ? -20.147 -5.901 86.077 1.00 26.67 ? 181 CYS A C 1 ATOM 1232 O O . CYS A 1 161 ? -19.817 -5.648 84.912 1.00 25.87 ? 181 CYS A O 1 ATOM 1233 C CB . CYS A 1 161 ? -21.931 -4.365 86.826 1.00 27.13 ? 181 CYS A CB 1 ATOM 1234 S SG . CYS A 1 161 ? -22.571 -3.203 88.014 1.00 28.89 ? 181 CYS A SG 1 ATOM 1235 N N . LEU A 1 162 ? -20.248 -7.134 86.558 1.00 26.04 ? 182 LEU A N 1 ATOM 1236 C CA . LEU A 1 162 ? -20.241 -8.283 85.682 1.00 25.82 ? 182 LEU A CA 1 ATOM 1237 C C . LEU A 1 162 ? -21.619 -8.402 85.064 1.00 25.71 ? 182 LEU A C 1 ATOM 1238 O O . LEU A 1 162 ? -22.610 -7.926 85.618 1.00 25.44 ? 182 LEU A O 1 ATOM 1239 C CB . LEU A 1 162 ? -19.894 -9.554 86.446 1.00 25.93 ? 182 LEU A CB 1 ATOM 1240 C CG . LEU A 1 162 ? -18.461 -9.594 86.970 1.00 25.80 ? 182 LEU A CG 1 ATOM 1241 C CD1 . LEU A 1 162 ? -18.257 -10.793 87.907 1.00 24.39 ? 182 LEU A CD1 1 ATOM 1242 C CD2 . LEU A 1 162 ? -17.495 -9.627 85.791 1.00 25.45 ? 182 LEU A CD2 1 ATOM 1243 N N . ALA A 1 163 ? -21.661 -8.999 83.885 1.00 25.39 ? 183 ALA A N 1 ATOM 1244 C CA . ALA A 1 163 ? -22.902 -9.268 83.211 1.00 25.31 ? 183 ALA A CA 1 ATOM 1245 C C . ALA A 1 163 ? -22.803 -10.678 82.669 1.00 25.48 ? 183 ALA A C 1 ATOM 1246 O O . ALA A 1 163 ? -21.725 -11.301 82.718 1.00 25.18 ? 183 ALA A O 1 ATOM 1247 C CB . ALA A 1 163 ? -23.123 -8.262 82.095 1.00 25.29 ? 183 ALA A CB 1 ATOM 1248 N N . PHE A 1 164 ? -23.922 -11.193 82.177 1.00 25.45 ? 184 PHE A N 1 ATOM 1249 C CA . PHE A 1 164 ? -23.925 -12.503 81.541 1.00 25.58 ? 184 PHE A CA 1 ATOM 1250 C C . PHE A 1 164 ? -24.703 -12.473 80.229 1.00 25.22 ? 184 PHE A C 1 ATOM 1251 O O . PHE A 1 164 ? -25.542 -11.613 80.015 1.00 25.15 ? 184 PHE A O 1 ATOM 1252 C CB . PHE A 1 164 ? -24.490 -13.574 82.484 1.00 25.69 ? 184 PHE A CB 1 ATOM 1253 C CG . PHE A 1 164 ? -25.946 -13.405 82.797 1.00 25.85 ? 184 PHE A CG 1 ATOM 1254 C CD1 . PHE A 1 164 ? -26.912 -14.008 82.004 1.00 26.49 ? 184 PHE A CD1 1 ATOM 1255 C CD2 . PHE A 1 164 ? -26.350 -12.629 83.869 1.00 26.35 ? 184 PHE A CD2 1 ATOM 1256 C CE1 . PHE A 1 164 ? -28.258 -13.856 82.284 1.00 27.43 ? 184 PHE A CE1 1 ATOM 1257 C CE2 . PHE A 1 164 ? -27.701 -12.462 84.151 1.00 27.27 ? 184 PHE A CE2 1 ATOM 1258 C CZ . PHE A 1 164 ? -28.655 -13.076 83.360 1.00 27.15 ? 184 PHE A CZ 1 ATOM 1259 N N . THR A 1 165 ? -24.379 -13.419 79.355 1.00 25.16 ? 185 THR A N 1 ATOM 1260 C CA . THR A 1 165 ? -25.118 -13.667 78.124 1.00 24.66 ? 185 THR A CA 1 ATOM 1261 C C . THR A 1 165 ? -25.574 -15.118 78.185 1.00 24.41 ? 185 THR A C 1 ATOM 1262 O O . THR A 1 165 ? -24.746 -16.015 78.310 1.00 23.96 ? 185 THR A O 1 ATOM 1263 C CB . THR A 1 165 ? -24.207 -13.476 76.895 1.00 24.88 ? 185 THR A CB 1 ATOM 1264 O OG1 . THR A 1 165 ? -23.837 -12.091 76.766 1.00 24.97 ? 185 THR A OG1 1 ATOM 1265 C CG2 . THR A 1 165 ? -24.888 -13.962 75.618 1.00 24.02 ? 185 THR A CG2 1 ATOM 1266 N N . ASP A 1 166 ? -26.878 -15.360 78.115 1.00 23.85 ? 186 ASP A N 1 ATOM 1267 C CA . ASP A 1 166 ? -27.359 -16.738 78.100 1.00 24.00 ? 186 ASP A CA 1 ATOM 1268 C C . ASP A 1 166 ? -27.338 -17.264 76.675 1.00 23.64 ? 186 ASP A C 1 ATOM 1269 O O . ASP A 1 166 ? -27.574 -16.517 75.720 1.00 23.89 ? 186 ASP A O 1 ATOM 1270 C CB . ASP A 1 166 ? -28.764 -16.866 78.682 1.00 23.99 ? 186 ASP A CB 1 ATOM 1271 C CG . ASP A 1 166 ? -29.767 -15.979 77.978 1.00 24.13 ? 186 ASP A CG 1 ATOM 1272 O OD1 . ASP A 1 166 ? -29.420 -14.810 77.729 1.00 24.48 ? 186 ASP A OD1 1 ATOM 1273 O OD2 . ASP A 1 166 ? -30.889 -16.439 77.703 1.00 23.83 ? 186 ASP A OD2 1 ATOM 1274 N N . VAL A 1 167 ? -27.037 -18.550 76.538 1.00 23.33 ? 187 VAL A N 1 ATOM 1275 C CA . VAL A 1 167 ? -27.062 -19.211 75.239 1.00 22.94 ? 187 VAL A CA 1 ATOM 1276 C C . VAL A 1 167 ? -28.221 -20.190 75.257 1.00 22.95 ? 187 VAL A C 1 ATOM 1277 O O . VAL A 1 167 ? -28.663 -20.602 76.326 1.00 23.36 ? 187 VAL A O 1 ATOM 1278 C CB . VAL A 1 167 ? -25.736 -19.949 74.932 1.00 22.80 ? 187 VAL A CB 1 ATOM 1279 C CG1 . VAL A 1 167 ? -24.575 -18.981 74.966 1.00 21.59 ? 187 VAL A CG1 1 ATOM 1280 C CG2 . VAL A 1 167 ? -25.515 -21.113 75.891 1.00 22.32 ? 187 VAL A CG2 1 ATOM 1281 N N . ALA A 1 168 ? -28.725 -20.525 74.075 1.00 22.80 ? 188 ALA A N 1 ATOM 1282 C CA . ALA A 1 168 ? -29.840 -21.452 73.918 1.00 22.34 ? 188 ALA A CA 1 ATOM 1283 C C . ALA A 1 168 ? -29.503 -22.451 72.793 1.00 22.31 ? 188 ALA A C 1 ATOM 1284 O O . ALA A 1 168 ? -28.642 -22.168 71.967 1.00 22.04 ? 188 ALA A O 1 ATOM 1285 C CB . ALA A 1 168 ? -31.097 -20.679 73.605 1.00 22.30 ? 188 ALA A CB 1 ATOM 1286 N N . PRO A 1 169 ? -30.158 -23.627 72.764 1.00 22.33 ? 189 PRO A N 1 ATOM 1287 C CA . PRO A 1 169 ? -31.193 -24.119 73.681 1.00 22.68 ? 189 PRO A CA 1 ATOM 1288 C C . PRO A 1 169 ? -30.642 -24.430 75.084 1.00 22.61 ? 189 PRO A C 1 ATOM 1289 O O . PRO A 1 169 ? -29.416 -24.373 75.309 1.00 21.66 ? 189 PRO A O 1 ATOM 1290 C CB . PRO A 1 169 ? -31.671 -25.406 73.008 1.00 22.60 ? 189 PRO A CB 1 ATOM 1291 C CG . PRO A 1 169 ? -30.456 -25.910 72.297 1.00 22.70 ? 189 PRO A CG 1 ATOM 1292 C CD . PRO A 1 169 ? -29.730 -24.676 71.820 1.00 22.51 ? 189 PRO A CD 1 ATOM 1293 N N . ARG A 1 170 ? -31.561 -24.770 75.986 1.00 22.66 ? 190 ARG A N 1 ATOM 1294 C CA . ARG A 1 170 ? -31.323 -24.738 77.425 1.00 23.28 ? 190 ARG A CA 1 ATOM 1295 C C . ARG A 1 170 ? -31.498 -26.145 78.017 1.00 23.58 ? 190 ARG A C 1 ATOM 1296 O O . ARG A 1 170 ? -32.505 -26.453 78.699 1.00 23.65 ? 190 ARG A O 1 ATOM 1297 C CB . ARG A 1 170 ? -32.275 -23.715 78.079 1.00 23.14 ? 190 ARG A CB 1 ATOM 1298 C CG . ARG A 1 170 ? -32.279 -22.368 77.356 1.00 23.09 ? 190 ARG A CG 1 ATOM 1299 C CD . ARG A 1 170 ? -33.363 -21.395 77.824 1.00 23.00 ? 190 ARG A CD 1 ATOM 1300 N NE . ARG A 1 170 ? -33.356 -20.170 77.007 1.00 22.38 ? 190 ARG A NE 1 ATOM 1301 C CZ . ARG A 1 170 ? -32.560 -19.116 77.197 1.00 22.28 ? 190 ARG A CZ 1 ATOM 1302 N NH1 . ARG A 1 170 ? -31.691 -19.087 78.202 1.00 22.34 ? 190 ARG A NH1 1 ATOM 1303 N NH2 . ARG A 1 170 ? -32.643 -18.067 76.377 1.00 20.81 ? 190 ARG A NH2 1 ATOM 1304 N N . GLY A 1 171 ? -30.515 -26.995 77.732 1.00 23.38 ? 191 GLY A N 1 ATOM 1305 C CA . GLY A 1 171 ? -30.521 -28.368 78.209 1.00 23.75 ? 191 GLY A CA 1 ATOM 1306 C C . GLY A 1 171 ? -30.164 -29.388 77.143 1.00 24.01 ? 191 GLY A C 1 ATOM 1307 O O . GLY A 1 171 ? -29.582 -29.047 76.108 1.00 24.10 ? 191 GLY A O 1 ATOM 1308 N N . VAL A 1 172 ? -30.512 -30.645 77.419 1.00 24.11 ? 192 VAL A N 1 ATOM 1309 C CA . VAL A 1 172 ? -30.206 -31.765 76.534 1.00 24.01 ? 192 VAL A CA 1 ATOM 1310 C C . VAL A 1 172 ? -31.448 -32.478 76.021 1.00 24.01 ? 192 VAL A C 1 ATOM 1311 O O . VAL A 1 172 ? -31.324 -33.424 75.251 1.00 24.45 ? 192 VAL A O 1 ATOM 1312 C CB . VAL A 1 172 ? -29.305 -32.803 77.238 1.00 24.40 ? 192 VAL A CB 1 ATOM 1313 C CG1 . VAL A 1 172 ? -27.965 -32.150 77.661 1.00 24.17 ? 192 VAL A CG1 1 ATOM 1314 C CG2 . VAL A 1 172 ? -30.035 -33.443 78.426 1.00 23.19 ? 192 VAL A CG2 1 ATOM 1315 N N . ALA A 1 173 ? -32.637 -32.026 76.419 1.00 23.85 ? 193 ALA A N 1 ATOM 1316 C CA . ALA A 1 173 ? -33.882 -32.669 76.003 1.00 24.00 ? 193 ALA A CA 1 ATOM 1317 C C . ALA A 1 173 ? -35.079 -31.774 76.231 1.00 24.24 ? 193 ALA A C 1 ATOM 1318 O O . ALA A 1 173 ? -35.043 -30.876 77.068 1.00 24.29 ? 193 ALA A O 1 ATOM 1319 C CB . ALA A 1 173 ? -34.084 -33.995 76.752 1.00 23.45 ? 193 ALA A CB 1 ATOM 1320 N N . SER A 1 174 ? -36.148 -32.056 75.491 1.00 24.88 ? 194 SER A N 1 ATOM 1321 C CA . SER A 1 174 ? -37.405 -31.326 75.583 1.00 25.30 ? 194 SER A CA 1 ATOM 1322 C C . SER A 1 174 ? -37.927 -31.255 77.015 1.00 25.28 ? 194 SER A C 1 ATOM 1323 O O . SER A 1 174 ? -37.937 -32.253 77.719 1.00 25.79 ? 194 SER A O 1 ATOM 1324 C CB . SER A 1 174 ? -38.449 -32.004 74.696 1.00 25.49 ? 194 SER A CB 1 ATOM 1325 O OG . SER A 1 174 ? -39.729 -31.438 74.899 1.00 27.62 ? 194 SER A OG 1 ATOM 1326 N N . GLY A 1 175 ? -38.362 -30.072 77.440 1.00 25.40 ? 195 GLY A N 1 ATOM 1327 C CA . GLY A 1 175 ? -38.876 -29.868 78.797 1.00 25.22 ? 195 GLY A CA 1 ATOM 1328 C C . GLY A 1 175 ? -37.871 -29.274 79.769 1.00 25.22 ? 195 GLY A C 1 ATOM 1329 O O . GLY A 1 175 ? -38.243 -28.853 80.863 1.00 25.33 ? 195 GLY A O 1 ATOM 1330 N N . GLN A 1 176 ? -36.599 -29.241 79.379 1.00 25.29 ? 196 GLN A N 1 ATOM 1331 C CA . GLN A 1 176 ? -35.554 -28.673 80.216 1.00 25.19 ? 196 GLN A CA 1 ATOM 1332 C C . GLN A 1 176 ? -35.407 -27.166 79.976 1.00 25.28 ? 196 GLN A C 1 ATOM 1333 O O . GLN A 1 176 ? -35.663 -26.654 78.878 1.00 25.24 ? 196 GLN A O 1 ATOM 1334 C CB . GLN A 1 176 ? -34.222 -29.382 79.961 1.00 25.12 ? 196 GLN A CB 1 ATOM 1335 C CG . GLN A 1 176 ? -34.238 -30.856 80.343 1.00 25.28 ? 196 GLN A CG 1 ATOM 1336 C CD . GLN A 1 176 ? -32.865 -31.529 80.289 1.00 25.82 ? 196 GLN A CD 1 ATOM 1337 O OE1 . GLN A 1 176 ? -31.841 -30.893 80.025 1.00 24.14 ? 196 GLN A OE1 1 ATOM 1338 N NE2 . GLN A 1 176 ? -32.849 -32.834 80.537 1.00 25.83 ? 196 GLN A NE2 1 ATOM 1339 N N . ARG A 1 177 ? -34.997 -26.466 81.022 1.00 25.04 ? 197 ARG A N 1 ATOM 1340 C CA . ARG A 1 177 ? -34.707 -25.046 80.949 1.00 24.56 ? 197 ARG A CA 1 ATOM 1341 C C . ARG A 1 177 ? -33.477 -24.813 81.811 1.00 24.21 ? 197 ARG A C 1 ATOM 1342 O O . ARG A 1 177 ? -33.548 -24.263 82.923 1.00 24.37 ? 197 ARG A O 1 ATOM 1343 C CB . ARG A 1 177 ? -35.916 -24.224 81.412 1.00 24.84 ? 197 ARG A CB 1 ATOM 1344 C CG . ARG A 1 177 ? -35.859 -22.743 81.013 1.00 25.24 ? 197 ARG A CG 1 ATOM 1345 C CD . ARG A 1 177 ? -37.146 -22.058 81.375 1.00 25.35 ? 197 ARG A CD 1 ATOM 1346 N NE . ARG A 1 177 ? -37.247 -20.694 80.855 1.00 24.75 ? 197 ARG A NE 1 ATOM 1347 C CZ . ARG A 1 177 ? -37.747 -20.359 79.666 1.00 23.85 ? 197 ARG A CZ 1 ATOM 1348 N NH1 . ARG A 1 177 ? -38.186 -21.281 78.812 1.00 24.08 ? 197 ARG A NH1 1 ATOM 1349 N NH2 . ARG A 1 177 ? -37.796 -19.079 79.316 1.00 23.57 ? 197 ARG A NH2 1 ATOM 1350 N N . ARG A 1 178 ? -32.351 -25.277 81.283 1.00 23.53 ? 198 ARG A N 1 ATOM 1351 C CA . ARG A 1 178 ? -31.064 -25.231 81.967 1.00 23.52 ? 198 ARG A CA 1 ATOM 1352 C C . ARG A 1 178 ? -30.085 -24.486 81.082 1.00 23.04 ? 198 ARG A C 1 ATOM 1353 O O . ARG A 1 178 ? -29.631 -25.032 80.080 1.00 22.87 ? 198 ARG A O 1 ATOM 1354 C CB . ARG A 1 178 ? -30.545 -26.651 82.208 1.00 23.50 ? 198 ARG A CB 1 ATOM 1355 C CG . ARG A 1 178 ? -31.483 -27.545 83.013 1.00 23.87 ? 198 ARG A CG 1 ATOM 1356 C CD . ARG A 1 178 ? -31.153 -29.011 82.761 1.00 24.41 ? 198 ARG A CD 1 ATOM 1357 N NE . ARG A 1 178 ? -29.840 -29.372 83.287 1.00 25.08 ? 198 ARG A NE 1 ATOM 1358 C CZ . ARG A 1 178 ? -29.120 -30.422 82.897 1.00 26.30 ? 198 ARG A CZ 1 ATOM 1359 N NH1 . ARG A 1 178 ? -29.548 -31.242 81.933 1.00 26.26 ? 198 ARG A NH1 1 ATOM 1360 N NH2 . ARG A 1 178 ? -27.946 -30.647 83.465 1.00 26.94 ? 198 ARG A NH2 1 ATOM 1361 N N . SER A 1 179 ? -29.773 -23.239 81.430 1.00 22.87 ? 199 SER A N 1 ATOM 1362 C CA . SER A 1 179 ? -29.027 -22.362 80.525 1.00 22.67 ? 199 SER A CA 1 ATOM 1363 C C . SER A 1 179 ? -27.563 -22.198 80.919 1.00 22.94 ? 199 SER A C 1 ATOM 1364 O O . SER A 1 179 ? -27.258 -21.941 82.083 1.00 23.08 ? 199 SER A O 1 ATOM 1365 C CB . SER A 1 179 ? -29.684 -20.988 80.474 1.00 22.35 ? 199 SER A CB 1 ATOM 1366 O OG . SER A 1 179 ? -30.989 -21.071 79.937 1.00 22.23 ? 199 SER A OG 1 ATOM 1367 N N . TRP A 1 180 ? -26.659 -22.331 79.949 1.00 22.89 ? 200 TRP A N 1 ATOM 1368 C CA . TRP A 1 180 ? -25.271 -21.927 80.162 1.00 22.97 ? 200 TRP A CA 1 ATOM 1369 C C . TRP A 1 180 ? -25.175 -20.411 80.044 1.00 22.93 ? 200 TRP A C 1 ATOM 1370 O O . TRP A 1 180 ? -25.787 -19.802 79.156 1.00 23.05 ? 200 TRP A O 1 ATOM 1371 C CB . TRP A 1 180 ? -24.320 -22.613 79.182 1.00 23.09 ? 200 TRP A CB 1 ATOM 1372 C CG . TRP A 1 180 ? -23.889 -23.941 79.678 1.00 23.94 ? 200 TRP A CG 1 ATOM 1373 C CD1 . TRP A 1 180 ? -24.344 -25.164 79.261 1.00 23.86 ? 200 TRP A CD1 1 ATOM 1374 C CD2 . TRP A 1 180 ? -22.931 -24.196 80.715 1.00 24.11 ? 200 TRP A CD2 1 ATOM 1375 N NE1 . TRP A 1 180 ? -23.722 -26.161 79.978 1.00 25.24 ? 200 TRP A NE1 1 ATOM 1376 C CE2 . TRP A 1 180 ? -22.852 -25.597 80.874 1.00 24.68 ? 200 TRP A CE2 1 ATOM 1377 C CE3 . TRP A 1 180 ? -22.131 -23.378 81.524 1.00 24.81 ? 200 TRP A CE3 1 ATOM 1378 C CZ2 . TRP A 1 180 ? -22.002 -26.200 81.811 1.00 24.79 ? 200 TRP A CZ2 1 ATOM 1379 C CZ3 . TRP A 1 180 ? -21.282 -23.983 82.462 1.00 24.16 ? 200 TRP A CZ3 1 ATOM 1380 C CH2 . TRP A 1 180 ? -21.227 -25.381 82.589 1.00 24.64 ? 200 TRP A CH2 1 ATOM 1381 N N . LEU A 1 181 ? -24.416 -19.803 80.946 1.00 22.88 ? 201 LEU A N 1 ATOM 1382 C CA . LEU A 1 181 ? -24.283 -18.353 80.988 1.00 22.82 ? 201 LEU A CA 1 ATOM 1383 C C . LEU A 1 181 ? -22.820 -17.986 80.867 1.00 22.76 ? 201 LEU A C 1 ATOM 1384 O O . LEU A 1 181 ? -21.993 -18.476 81.633 1.00 23.33 ? 201 LEU A O 1 ATOM 1385 C CB . LEU A 1 181 ? -24.861 -17.804 82.292 1.00 22.59 ? 201 LEU A CB 1 ATOM 1386 C CG . LEU A 1 181 ? -26.265 -18.275 82.668 1.00 22.51 ? 201 LEU A CG 1 ATOM 1387 C CD1 . LEU A 1 181 ? -26.722 -17.557 83.921 1.00 23.35 ? 201 LEU A CD1 1 ATOM 1388 C CD2 . LEU A 1 181 ? -27.288 -18.103 81.539 1.00 19.88 ? 201 LEU A CD2 1 ATOM 1389 N N . ILE A 1 182 ? -22.511 -17.142 79.890 1.00 22.85 ? 202 ILE A N 1 ATOM 1390 C CA . ILE A 1 182 ? -21.170 -16.607 79.701 1.00 22.73 ? 202 ILE A CA 1 ATOM 1391 C C . ILE A 1 182 ? -21.026 -15.326 80.520 1.00 23.07 ? 202 ILE A C 1 ATOM 1392 O O . ILE A 1 182 ? -21.754 -14.350 80.288 1.00 23.64 ? 202 ILE A O 1 ATOM 1393 C CB . ILE A 1 182 ? -20.905 -16.265 78.227 1.00 22.78 ? 202 ILE A CB 1 ATOM 1394 C CG1 . ILE A 1 182 ? -21.071 -17.507 77.331 1.00 22.77 ? 202 ILE A CG1 1 ATOM 1395 C CG2 . ILE A 1 182 ? -19.507 -15.693 78.069 1.00 21.96 ? 202 ILE A CG2 1 ATOM 1396 C CD1 . ILE A 1 182 ? -21.245 -17.175 75.840 1.00 22.15 ? 202 ILE A CD1 1 ATOM 1397 N N . ILE A 1 183 ? -20.090 -15.325 81.468 1.00 22.81 ? 203 ILE A N 1 ATOM 1398 C CA . ILE A 1 183 ? -19.845 -14.169 82.307 1.00 22.15 ? 203 ILE A CA 1 ATOM 1399 C C . ILE A 1 183 ? -18.890 -13.214 81.587 1.00 22.63 ? 203 ILE A C 1 ATOM 1400 O O . ILE A 1 183 ? -17.852 -13.625 81.045 1.00 22.59 ? 203 ILE A O 1 ATOM 1401 C CB . ILE A 1 183 ? -19.251 -14.559 83.690 1.00 22.35 ? 203 ILE A CB 1 ATOM 1402 C CG1 . ILE A 1 183 ? -20.071 -15.677 84.354 1.00 21.35 ? 203 ILE A CG1 1 ATOM 1403 C CG2 . ILE A 1 183 ? -19.204 -13.333 84.619 1.00 20.46 ? 203 ILE A CG2 1 ATOM 1404 C CD1 . ILE A 1 183 ? -21.540 -15.372 84.467 1.00 20.44 ? 203 ILE A CD1 1 ATOM 1405 N N . GLN A 1 184 ? -19.260 -11.939 81.593 1.00 22.68 ? 204 GLN A N 1 ATOM 1406 C CA . GLN A 1 184 ? -18.528 -10.893 80.895 1.00 22.94 ? 204 GLN A CA 1 ATOM 1407 C C . GLN A 1 184 ? -18.412 -9.656 81.780 1.00 23.11 ? 204 GLN A C 1 ATOM 1408 O O . GLN A 1 184 ? -19.172 -9.482 82.747 1.00 22.07 ? 204 GLN A O 1 ATOM 1409 C CB . GLN A 1 184 ? -19.245 -10.497 79.601 1.00 22.95 ? 204 GLN A CB 1 ATOM 1410 C CG . GLN A 1 184 ? -19.390 -11.611 78.548 1.00 22.71 ? 204 GLN A CG 1 ATOM 1411 C CD . GLN A 1 184 ? -20.726 -11.543 77.813 1.00 22.27 ? 204 GLN A CD 1 ATOM 1412 O OE1 . GLN A 1 184 ? -21.724 -11.059 78.354 1.00 19.64 ? 204 GLN A OE1 1 ATOM 1413 N NE2 . GLN A 1 184 ? -20.748 -12.031 76.575 1.00 20.88 ? 204 GLN A NE2 1 ATOM 1414 N N . ARG A 1 185 ? -17.449 -8.806 81.442 1.00 23.25 ? 205 ARG A N 1 ATOM 1415 C CA . ARG A 1 185 ? -17.343 -7.492 82.050 1.00 24.00 ? 205 ARG A CA 1 ATOM 1416 C C . ARG A 1 185 ? -18.223 -6.511 81.313 1.00 23.87 ? 205 ARG A C 1 ATOM 1417 O O . ARG A 1 185 ? -18.138 -6.386 80.094 1.00 23.95 ? 205 ARG A O 1 ATOM 1418 C CB . ARG A 1 185 ? -15.893 -7.015 82.041 1.00 23.95 ? 205 ARG A CB 1 ATOM 1419 C CG . ARG A 1 185 ? -15.010 -7.897 82.879 1.00 25.15 ? 205 ARG A CG 1 ATOM 1420 C CD . ARG A 1 185 ? -13.786 -7.176 83.369 1.00 26.68 ? 205 ARG A CD 1 ATOM 1421 N NE . ARG A 1 185 ? -12.815 -6.972 82.308 1.00 27.91 ? 205 ARG A NE 1 ATOM 1422 C CZ . ARG A 1 185 ? -11.540 -6.660 82.505 1.00 29.36 ? 205 ARG A CZ 1 ATOM 1423 N NH1 . ARG A 1 185 ? -11.062 -6.497 83.731 1.00 30.58 ? 205 ARG A NH1 1 ATOM 1424 N NH2 . ARG A 1 185 ? -10.737 -6.498 81.466 1.00 30.58 ? 205 ARG A NH2 1 ATOM 1425 N N . TYR A 1 186 ? -19.068 -5.807 82.056 1.00 24.42 ? 206 TYR A N 1 ATOM 1426 C CA . TYR A 1 186 ? -20.007 -4.870 81.453 1.00 24.74 ? 206 TYR A CA 1 ATOM 1427 C C . TYR A 1 186 ? -19.344 -3.533 81.142 1.00 24.73 ? 206 TYR A C 1 ATOM 1428 O O . TYR A 1 186 ? -19.515 -2.550 81.871 1.00 24.57 ? 206 TYR A O 1 ATOM 1429 C CB . TYR A 1 186 ? -21.231 -4.675 82.352 1.00 25.11 ? 206 TYR A CB 1 ATOM 1430 C CG . TYR A 1 186 ? -22.340 -3.892 81.697 1.00 26.69 ? 206 TYR A CG 1 ATOM 1431 C CD1 . TYR A 1 186 ? -22.848 -4.273 80.463 1.00 28.34 ? 206 TYR A CD1 1 ATOM 1432 C CD2 . TYR A 1 186 ? -22.873 -2.765 82.303 1.00 29.25 ? 206 TYR A CD2 1 ATOM 1433 C CE1 . TYR A 1 186 ? -23.860 -3.558 79.854 1.00 30.32 ? 206 TYR A CE1 1 ATOM 1434 C CE2 . TYR A 1 186 ? -23.896 -2.043 81.702 1.00 31.01 ? 206 TYR A CE2 1 ATOM 1435 C CZ . TYR A 1 186 ? -24.381 -2.449 80.475 1.00 31.21 ? 206 TYR A CZ 1 ATOM 1436 O OH . TYR A 1 186 ? -25.393 -1.754 79.862 1.00 35.04 ? 206 TYR A OH 1 ATOM 1437 N N . VAL A 1 187 ? -18.580 -3.526 80.051 1.00 24.56 ? 207 VAL A N 1 ATOM 1438 C CA . VAL A 1 187 ? -17.964 -2.323 79.498 1.00 24.50 ? 207 VAL A CA 1 ATOM 1439 C C . VAL A 1 187 ? -18.501 -2.104 78.075 1.00 24.66 ? 207 VAL A C 1 ATOM 1440 O O . VAL A 1 187 ? -19.270 -2.911 77.571 1.00 25.03 ? 207 VAL A O 1 ATOM 1441 C CB . VAL A 1 187 ? -16.426 -2.447 79.445 1.00 24.46 ? 207 VAL A CB 1 ATOM 1442 C CG1 . VAL A 1 187 ? -15.844 -2.530 80.855 1.00 23.62 ? 207 VAL A CG1 1 ATOM 1443 C CG2 . VAL A 1 187 ? -16.021 -3.661 78.597 1.00 23.77 ? 207 VAL A CG2 1 ATOM 1444 N N . GLU A 1 188 ? -18.087 -1.016 77.438 1.00 24.71 ? 208 GLU A N 1 ATOM 1445 C CA . GLU A 1 188 ? -18.478 -0.711 76.071 1.00 24.78 ? 208 GLU A CA 1 ATOM 1446 C C . GLU A 1 188 ? -18.150 -1.885 75.160 1.00 24.65 ? 208 GLU A C 1 ATOM 1447 O O . GLU A 1 188 ? -16.988 -2.305 75.067 1.00 24.14 ? 208 GLU A O 1 ATOM 1448 C CB . GLU A 1 188 ? -17.733 0.530 75.583 1.00 25.18 ? 208 GLU A CB 1 ATOM 1449 C CG . GLU A 1 188 ? -18.092 0.986 74.170 1.00 26.32 ? 208 GLU A CG 1 ATOM 1450 C CD . GLU A 1 188 ? -17.222 2.135 73.692 1.00 27.34 ? 208 GLU A CD 1 ATOM 1451 O OE1 . GLU A 1 188 ? -16.328 2.566 74.450 1.00 28.27 ? 208 GLU A OE1 1 ATOM 1452 O OE2 . GLU A 1 188 ? -17.438 2.609 72.553 1.00 27.82 ? 208 GLU A OE2 1 ATOM 1453 N N . GLY A 1 189 ? -19.173 -2.408 74.487 1.00 24.23 ? 209 GLY A N 1 ATOM 1454 C CA . GLY A 1 189 ? -19.006 -3.573 73.631 1.00 24.02 ? 209 GLY A CA 1 ATOM 1455 C C . GLY A 1 189 ? -18.731 -4.799 74.475 1.00 23.47 ? 209 GLY A C 1 ATOM 1456 O O . GLY A 1 189 ? -17.879 -5.625 74.137 1.00 23.50 ? 209 GLY A O 1 ATOM 1457 N N . TYR A 1 190 ? -19.471 -4.901 75.577 1.00 23.04 ? 210 TYR A N 1 ATOM 1458 C CA . TYR A 1 190 ? -19.290 -5.945 76.596 1.00 22.44 ? 210 TYR A CA 1 ATOM 1459 C C . TYR A 1 190 ? -19.326 -7.362 76.054 1.00 21.73 ? 210 TYR A C 1 ATOM 1460 O O . TYR A 1 190 ? -18.777 -8.261 76.675 1.00 21.11 ? 210 TYR A O 1 ATOM 1461 C CB . TYR A 1 190 ? -20.360 -5.814 77.680 1.00 22.81 ? 210 TYR A CB 1 ATOM 1462 C CG . TYR A 1 190 ? -21.771 -5.951 77.178 1.00 23.85 ? 210 TYR A CG 1 ATOM 1463 C CD1 . TYR A 1 190 ? -22.436 -7.162 77.246 1.00 25.50 ? 210 TYR A CD1 1 ATOM 1464 C CD2 . TYR A 1 190 ? -22.453 -4.858 76.658 1.00 25.98 ? 210 TYR A CD2 1 ATOM 1465 C CE1 . TYR A 1 190 ? -23.751 -7.287 76.792 1.00 27.07 ? 210 TYR A CE1 1 ATOM 1466 C CE2 . TYR A 1 190 ? -23.758 -4.973 76.201 1.00 27.24 ? 210 TYR A CE2 1 ATOM 1467 C CZ . TYR A 1 190 ? -24.402 -6.191 76.265 1.00 27.75 ? 210 TYR A CZ 1 ATOM 1468 O OH . TYR A 1 190 ? -25.704 -6.301 75.818 1.00 29.34 ? 210 TYR A OH 1 ATOM 1469 N N . PHE A 1 191 ? -19.994 -7.556 74.910 1.00 21.23 ? 211 PHE A N 1 ATOM 1470 C CA . PHE A 1 191 ? -20.035 -8.843 74.215 1.00 20.73 ? 211 PHE A CA 1 ATOM 1471 C C . PHE A 1 191 ? -18.660 -9.471 74.035 1.00 20.47 ? 211 PHE A C 1 ATOM 1472 O O . PHE A 1 191 ? -18.532 -10.689 74.002 1.00 20.72 ? 211 PHE A O 1 ATOM 1473 C CB . PHE A 1 191 ? -20.650 -8.696 72.819 1.00 20.62 ? 211 PHE A CB 1 ATOM 1474 C CG . PHE A 1 191 ? -21.925 -7.908 72.785 1.00 20.86 ? 211 PHE A CG 1 ATOM 1475 C CD1 . PHE A 1 191 ? -21.935 -6.610 72.284 1.00 20.55 ? 211 PHE A CD1 1 ATOM 1476 C CD2 . PHE A 1 191 ? -23.115 -8.461 73.229 1.00 21.10 ? 211 PHE A CD2 1 ATOM 1477 C CE1 . PHE A 1 191 ? -23.099 -5.884 72.235 1.00 20.50 ? 211 PHE A CE1 1 ATOM 1478 C CE2 . PHE A 1 191 ? -24.296 -7.730 73.191 1.00 21.31 ? 211 PHE A CE2 1 ATOM 1479 C CZ . PHE A 1 191 ? -24.288 -6.440 72.699 1.00 21.50 ? 211 PHE A CZ 1 ATOM 1480 N N . LEU A 1 192 ? -17.647 -8.635 73.874 1.00 20.69 ? 212 LEU A N 1 ATOM 1481 C CA . LEU A 1 192 ? -16.289 -9.090 73.597 1.00 20.84 ? 212 LEU A CA 1 ATOM 1482 C C . LEU A 1 192 ? -15.415 -9.192 74.846 1.00 21.24 ? 212 LEU A C 1 ATOM 1483 O O . LEU A 1 192 ? -14.188 -9.289 74.729 1.00 21.59 ? 212 LEU A O 1 ATOM 1484 C CB . LEU A 1 192 ? -15.629 -8.139 72.591 1.00 20.52 ? 212 LEU A CB 1 ATOM 1485 C CG . LEU A 1 192 ? -16.409 -7.912 71.289 1.00 20.58 ? 212 LEU A CG 1 ATOM 1486 C CD1 . LEU A 1 192 ? -15.576 -7.109 70.294 1.00 20.77 ? 212 LEU A CD1 1 ATOM 1487 C CD2 . LEU A 1 192 ? -16.845 -9.246 70.684 1.00 19.89 ? 212 LEU A CD2 1 ATOM 1488 N N . HIS A 1 193 ? -16.034 -9.212 76.026 1.00 21.46 ? 213 HIS A N 1 ATOM 1489 C CA . HIS A 1 193 ? -15.290 -9.235 77.287 1.00 21.63 ? 213 HIS A CA 1 ATOM 1490 C C . HIS A 1 193 ? -15.662 -10.389 78.233 1.00 22.18 ? 213 HIS A C 1 ATOM 1491 O O . HIS A 1 193 ? -16.092 -10.159 79.368 1.00 22.09 ? 213 HIS A O 1 ATOM 1492 C CB . HIS A 1 193 ? -15.485 -7.887 77.983 1.00 21.87 ? 213 HIS A CB 1 ATOM 1493 C CG . HIS A 1 193 ? -14.863 -6.744 77.248 1.00 21.06 ? 213 HIS A CG 1 ATOM 1494 N ND1 . HIS A 1 193 ? -13.568 -6.340 77.472 1.00 21.35 ? 213 HIS A ND1 1 ATOM 1495 C CD2 . HIS A 1 193 ? -15.349 -5.933 76.277 1.00 22.01 ? 213 HIS A CD2 1 ATOM 1496 C CE1 . HIS A 1 193 ? -13.287 -5.315 76.686 1.00 22.44 ? 213 HIS A CE1 1 ATOM 1497 N NE2 . HIS A 1 193 ? -14.347 -5.055 75.942 1.00 21.39 ? 213 HIS A NE2 1 ATOM 1498 N N . PRO A 1 194 ? -15.484 -11.642 77.778 1.00 22.48 ? 214 PRO A N 1 ATOM 1499 C CA . PRO A 1 194 ? -15.683 -12.782 78.656 1.00 22.68 ? 214 PRO A CA 1 ATOM 1500 C C . PRO A 1 194 ? -14.588 -12.865 79.715 1.00 23.13 ? 214 PRO A C 1 ATOM 1501 O O . PRO A 1 194 ? -13.439 -12.460 79.454 1.00 22.70 ? 214 PRO A O 1 ATOM 1502 C CB . PRO A 1 194 ? -15.581 -13.971 77.709 1.00 22.87 ? 214 PRO A CB 1 ATOM 1503 C CG . PRO A 1 194 ? -14.662 -13.506 76.650 1.00 22.92 ? 214 PRO A CG 1 ATOM 1504 C CD . PRO A 1 194 ? -15.000 -12.058 76.455 1.00 22.82 ? 214 PRO A CD 1 ATOM 1505 N N . THR A 1 195 ? -14.944 -13.396 80.886 1.00 23.28 ? 215 THR A N 1 ATOM 1506 C CA . THR A 1 195 ? -14.015 -13.482 82.012 1.00 23.57 ? 215 THR A CA 1 ATOM 1507 C C . THR A 1 195 ? -13.322 -14.828 82.110 1.00 24.07 ? 215 THR A C 1 ATOM 1508 O O . THR A 1 195 ? -12.262 -14.943 82.724 1.00 24.24 ? 215 THR A O 1 ATOM 1509 C CB . THR A 1 195 ? -14.727 -13.190 83.338 1.00 23.57 ? 215 THR A CB 1 ATOM 1510 O OG1 . THR A 1 195 ? -15.775 -14.146 83.550 1.00 22.00 ? 215 THR A OG1 1 ATOM 1511 C CG2 . THR A 1 195 ? -15.305 -11.780 83.311 1.00 23.05 ? 215 THR A CG2 1 ATOM 1512 N N . GLY A 1 196 ? -13.907 -15.846 81.487 1.00 24.68 ? 216 GLY A N 1 ATOM 1513 C CA . GLY A 1 196 ? -13.389 -17.208 81.593 1.00 24.57 ? 216 GLY A CA 1 ATOM 1514 C C . GLY A 1 196 ? -14.259 -18.080 82.467 1.00 24.61 ? 216 GLY A C 1 ATOM 1515 O O . GLY A 1 196 ? -14.038 -19.282 82.544 1.00 25.17 ? 216 GLY A O 1 ATOM 1516 N N . LEU A 1 197 ? -15.248 -17.481 83.127 1.00 24.76 ? 217 LEU A N 1 ATOM 1517 C CA . LEU A 1 197 ? -16.231 -18.233 83.906 1.00 24.62 ? 217 LEU A CA 1 ATOM 1518 C C . LEU A 1 197 ? -17.485 -18.425 83.077 1.00 24.25 ? 217 LEU A C 1 ATOM 1519 O O . LEU A 1 197 ? -17.918 -17.517 82.385 1.00 24.34 ? 217 LEU A O 1 ATOM 1520 C CB . LEU A 1 197 ? -16.579 -17.487 85.199 1.00 24.74 ? 217 LEU A CB 1 ATOM 1521 C CG . LEU A 1 197 ? -17.533 -18.174 86.180 1.00 25.12 ? 217 LEU A CG 1 ATOM 1522 C CD1 . LEU A 1 197 ? -16.899 -19.444 86.816 1.00 25.94 ? 217 LEU A CD1 1 ATOM 1523 C CD2 . LEU A 1 197 ? -17.968 -17.191 87.259 1.00 24.39 ? 217 LEU A CD2 1 ATOM 1524 N N . GLU A 1 198 ? -18.058 -19.617 83.138 1.00 24.19 ? 218 GLU A N 1 ATOM 1525 C CA . GLU A 1 198 ? -19.379 -19.856 82.588 1.00 24.28 ? 218 GLU A CA 1 ATOM 1526 C C . GLU A 1 198 ? -20.176 -20.622 83.622 1.00 24.20 ? 218 GLU A C 1 ATOM 1527 O O . GLU A 1 198 ? -19.606 -21.442 84.337 1.00 24.68 ? 218 GLU A O 1 ATOM 1528 C CB . GLU A 1 198 ? -19.269 -20.662 81.300 1.00 24.41 ? 218 GLU A CB 1 ATOM 1529 C CG . GLU A 1 198 ? -18.433 -19.985 80.232 1.00 24.33 ? 218 GLU A CG 1 ATOM 1530 C CD . GLU A 1 198 ? -18.508 -20.690 78.892 1.00 25.32 ? 218 GLU A CD 1 ATOM 1531 O OE1 . GLU A 1 198 ? -19.027 -21.823 78.842 1.00 25.49 ? 218 GLU A OE1 1 ATOM 1532 O OE2 . GLU A 1 198 ? -18.043 -20.107 77.886 1.00 25.97 ? 218 GLU A OE2 1 ATOM 1533 N N . LEU A 1 199 ? -21.479 -20.369 83.701 1.00 24.13 ? 219 LEU A N 1 ATOM 1534 C CA . LEU A 1 199 ? -22.336 -21.001 84.714 1.00 24.12 ? 219 LEU A CA 1 ATOM 1535 C C . LEU A 1 199 ? -23.598 -21.638 84.121 1.00 23.77 ? 219 LEU A C 1 ATOM 1536 O O . LEU A 1 199 ? -24.271 -21.031 83.297 1.00 23.43 ? 219 LEU A O 1 ATOM 1537 C CB . LEU A 1 199 ? -22.761 -19.967 85.762 1.00 24.14 ? 219 LEU A CB 1 ATOM 1538 C CG . LEU A 1 199 ? -21.664 -19.102 86.378 1.00 24.99 ? 219 LEU A CG 1 ATOM 1539 C CD1 . LEU A 1 199 ? -22.287 -18.013 87.281 1.00 25.46 ? 219 LEU A CD1 1 ATOM 1540 C CD2 . LEU A 1 199 ? -20.664 -19.965 87.147 1.00 26.12 ? 219 LEU A CD2 1 ATOM 1541 N N . LEU A 1 200 ? -23.920 -22.853 84.566 1.00 23.38 ? 220 LEU A N 1 ATOM 1542 C CA . LEU A 1 200 ? -25.144 -23.532 84.166 1.00 23.33 ? 220 LEU A CA 1 ATOM 1543 C C . LEU A 1 200 ? -26.188 -23.345 85.255 1.00 23.65 ? 220 LEU A C 1 ATOM 1544 O O . LEU A 1 200 ? -25.966 -23.744 86.402 1.00 23.87 ? 220 LEU A O 1 ATOM 1545 C CB . LEU A 1 200 ? -24.903 -25.029 83.959 1.00 23.13 ? 220 LEU A CB 1 ATOM 1546 C CG . LEU A 1 200 ? -26.107 -25.874 83.505 1.00 22.64 ? 220 LEU A CG 1 ATOM 1547 C CD1 . LEU A 1 200 ? -26.651 -25.406 82.147 1.00 20.02 ? 220 LEU A CD1 1 ATOM 1548 C CD2 . LEU A 1 200 ? -25.749 -27.366 83.464 1.00 20.52 ? 220 LEU A CD2 1 ATOM 1549 N N . VAL A 1 201 ? -27.323 -22.757 84.896 1.00 23.66 ? 221 VAL A N 1 ATOM 1550 C CA . VAL A 1 201 ? -28.415 -22.528 85.842 1.00 23.96 ? 221 VAL A CA 1 ATOM 1551 C C . VAL A 1 201 ? -29.661 -23.266 85.398 1.00 24.66 ? 221 VAL A C 1 ATOM 1552 O O . VAL A 1 201 ? -30.082 -23.130 84.250 1.00 24.76 ? 221 VAL A O 1 ATOM 1553 C CB . VAL A 1 201 ? -28.741 -21.017 85.961 1.00 23.84 ? 221 VAL A CB 1 ATOM 1554 C CG1 . VAL A 1 201 ? -29.983 -20.794 86.812 1.00 23.55 ? 221 VAL A CG1 1 ATOM 1555 C CG2 . VAL A 1 201 ? -27.532 -20.251 86.520 1.00 22.93 ? 221 VAL A CG2 1 ATOM 1556 N N . ASP A 1 202 ? -30.241 -24.051 86.303 1.00 25.48 ? 222 ASP A N 1 ATOM 1557 C CA . ASP A 1 202 ? -31.569 -24.640 86.095 1.00 26.06 ? 222 ASP A CA 1 ATOM 1558 C C . ASP A 1 202 ? -32.610 -23.629 86.567 1.00 26.38 ? 222 ASP A C 1 ATOM 1559 O O . ASP A 1 202 ? -32.745 -23.393 87.775 1.00 26.89 ? 222 ASP A O 1 ATOM 1560 C CB . ASP A 1 202 ? -31.722 -25.955 86.868 1.00 26.11 ? 222 ASP A CB 1 ATOM 1561 C CG . ASP A 1 202 ? -33.050 -26.669 86.585 1.00 27.50 ? 222 ASP A CG 1 ATOM 1562 O OD1 . ASP A 1 202 ? -33.922 -26.127 85.863 1.00 29.53 ? 222 ASP A OD1 1 ATOM 1563 O OD2 . ASP A 1 202 ? -33.229 -27.789 87.101 1.00 29.21 ? 222 ASP A OD2 1 ATOM 1564 N N . HIS A 1 203 ? -33.330 -23.029 85.620 1.00 26.24 ? 223 HIS A N 1 ATOM 1565 C CA . HIS A 1 203 ? -34.372 -22.041 85.946 1.00 26.36 ? 223 HIS A CA 1 ATOM 1566 C C . HIS A 1 203 ? -35.764 -22.480 85.455 1.00 26.84 ? 223 HIS A C 1 ATOM 1567 O O . HIS A 1 203 ? -36.584 -21.670 85.050 1.00 27.22 ? 223 HIS A O 1 ATOM 1568 C CB . HIS A 1 203 ? -33.989 -20.617 85.471 1.00 26.29 ? 223 HIS A CB 1 ATOM 1569 C CG . HIS A 1 203 ? -33.614 -20.510 84.020 1.00 24.59 ? 223 HIS A CG 1 ATOM 1570 N ND1 . HIS A 1 203 ? -34.333 -19.751 83.125 1.00 23.87 ? 223 HIS A ND1 1 ATOM 1571 C CD2 . HIS A 1 203 ? -32.565 -21.010 83.326 1.00 23.85 ? 223 HIS A CD2 1 ATOM 1572 C CE1 . HIS A 1 203 ? -33.764 -19.813 81.935 1.00 23.63 ? 223 HIS A CE1 1 ATOM 1573 N NE2 . HIS A 1 203 ? -32.692 -20.577 82.027 1.00 22.73 ? 223 HIS A NE2 1 ATOM 1574 N N . GLY A 1 204 ? -36.027 -23.779 85.547 1.00 27.73 ? 224 GLY A N 1 ATOM 1575 C CA . GLY A 1 204 ? -37.293 -24.353 85.098 1.00 28.46 ? 224 GLY A CA 1 ATOM 1576 C C . GLY A 1 204 ? -38.506 -24.039 85.964 1.00 28.90 ? 224 GLY A C 1 ATOM 1577 O O . GLY A 1 204 ? -39.587 -23.759 85.435 1.00 28.94 ? 224 GLY A O 1 ATOM 1578 N N A SER A 1 205 ? -38.328 -24.077 87.285 0.50 29.11 ? 225 SER A N 1 ATOM 1579 N N B SER A 1 205 ? -38.344 -24.085 87.286 0.50 29.23 ? 225 SER A N 1 ATOM 1580 C CA A SER A 1 205 ? -39.446 -23.912 88.219 0.50 29.25 ? 225 SER A CA 1 ATOM 1581 C CA B SER A 1 205 ? -39.496 -23.957 88.185 0.50 29.50 ? 225 SER A CA 1 ATOM 1582 C C A SER A 1 205 ? -39.993 -22.491 88.213 0.50 29.46 ? 225 SER A C 1 ATOM 1583 C C B SER A 1 205 ? -39.992 -22.516 88.251 0.50 29.58 ? 225 SER A C 1 ATOM 1584 O O A SER A 1 205 ? -39.240 -21.533 88.040 0.50 29.58 ? 225 SER A O 1 ATOM 1585 O O B SER A 1 205 ? -39.205 -21.574 88.169 0.50 29.70 ? 225 SER A O 1 ATOM 1586 C CB A SER A 1 205 ? -39.016 -24.279 89.644 0.50 29.30 ? 225 SER A CB 1 ATOM 1587 C CB B SER A 1 205 ? -39.162 -24.467 89.594 0.50 29.57 ? 225 SER A CB 1 ATOM 1588 O OG A SER A 1 205 ? -40.061 -24.028 90.572 0.50 28.43 ? 225 SER A OG 1 ATOM 1589 O OG B SER A 1 205 ? -39.011 -23.401 90.517 0.50 29.64 ? 225 SER A OG 1 ATOM 1590 N N . THR A 1 206 ? -41.302 -22.358 88.410 1.00 29.82 ? 226 THR A N 1 ATOM 1591 C CA . THR A 1 206 ? -41.935 -21.034 88.509 1.00 30.37 ? 226 THR A CA 1 ATOM 1592 C C . THR A 1 206 ? -41.628 -20.346 89.847 1.00 30.97 ? 226 THR A C 1 ATOM 1593 O O . THR A 1 206 ? -41.927 -19.168 90.018 1.00 30.96 ? 226 THR A O 1 ATOM 1594 C CB . THR A 1 206 ? -43.458 -21.109 88.321 1.00 30.38 ? 226 THR A CB 1 ATOM 1595 O OG1 . THR A 1 206 ? -44.026 -22.001 89.290 1.00 30.86 ? 226 THR A OG1 1 ATOM 1596 C CG2 . THR A 1 206 ? -43.797 -21.592 86.927 1.00 30.20 ? 226 THR A CG2 1 ATOM 1597 N N . ASP A 1 207 ? -41.052 -21.093 90.789 1.00 31.30 ? 227 ASP A N 1 ATOM 1598 C CA . ASP A 1 207 ? -40.517 -20.527 92.011 1.00 31.84 ? 227 ASP A CA 1 ATOM 1599 C C . ASP A 1 207 ? -39.010 -20.335 91.843 1.00 31.70 ? 227 ASP A C 1 ATOM 1600 O O . ASP A 1 207 ? -38.246 -21.298 91.909 1.00 31.55 ? 227 ASP A O 1 ATOM 1601 C CB . ASP A 1 207 ? -40.814 -21.458 93.197 1.00 32.09 ? 227 ASP A CB 1 ATOM 1602 C CG . ASP A 1 207 ? -40.208 -20.961 94.511 1.00 33.43 ? 227 ASP A CG 1 ATOM 1603 O OD1 . ASP A 1 207 ? -39.625 -19.855 94.546 1.00 34.63 ? 227 ASP A OD1 1 ATOM 1604 O OD2 . ASP A 1 207 ? -40.316 -21.686 95.522 1.00 36.50 ? 227 ASP A OD2 1 ATOM 1605 N N . ALA A 1 208 ? -38.588 -19.088 91.661 1.00 31.64 ? 228 ALA A N 1 ATOM 1606 C CA . ALA A 1 208 ? -37.171 -18.768 91.440 1.00 32.04 ? 228 ALA A CA 1 ATOM 1607 C C . ALA A 1 208 ? -36.258 -19.149 92.605 1.00 32.23 ? 228 ALA A C 1 ATOM 1608 O O . ALA A 1 208 ? -35.046 -19.212 92.434 1.00 32.24 ? 228 ALA A O 1 ATOM 1609 C CB . ALA A 1 208 ? -37.002 -17.291 91.114 1.00 32.13 ? 228 ALA A CB 1 ATOM 1610 N N . GLY A 1 209 ? -36.831 -19.375 93.787 1.00 32.44 ? 229 GLY A N 1 ATOM 1611 C CA . GLY A 1 209 ? -36.072 -19.857 94.936 1.00 32.46 ? 229 GLY A CA 1 ATOM 1612 C C . GLY A 1 209 ? -35.522 -21.263 94.755 1.00 32.66 ? 229 GLY A C 1 ATOM 1613 O O . GLY A 1 209 ? -34.572 -21.654 95.441 1.00 32.82 ? 229 GLY A O 1 ATOM 1614 N N . HIS A 1 210 ? -36.119 -22.031 93.844 1.00 32.65 ? 230 HIS A N 1 ATOM 1615 C CA . HIS A 1 210 ? -35.617 -23.362 93.516 1.00 32.80 ? 230 HIS A CA 1 ATOM 1616 C C . HIS A 1 210 ? -34.474 -23.350 92.504 1.00 32.05 ? 230 HIS A C 1 ATOM 1617 O O . HIS A 1 210 ? -33.826 -24.371 92.300 1.00 32.36 ? 230 HIS A O 1 ATOM 1618 C CB . HIS A 1 210 ? -36.740 -24.235 92.975 1.00 33.17 ? 230 HIS A CB 1 ATOM 1619 C CG . HIS A 1 210 ? -37.798 -24.549 93.982 1.00 35.49 ? 230 HIS A CG 1 ATOM 1620 N ND1 . HIS A 1 210 ? -39.092 -24.868 93.626 1.00 37.61 ? 230 HIS A ND1 1 ATOM 1621 C CD2 . HIS A 1 210 ? -37.755 -24.595 95.335 1.00 37.45 ? 230 HIS A CD2 1 ATOM 1622 C CE1 . HIS A 1 210 ? -39.799 -25.102 94.718 1.00 38.77 ? 230 HIS A CE1 1 ATOM 1623 N NE2 . HIS A 1 210 ? -39.012 -24.939 95.768 1.00 38.56 ? 230 HIS A NE2 1 ATOM 1624 N N . TRP A 1 211 ? -34.239 -22.209 91.864 1.00 31.15 ? 231 TRP A N 1 ATOM 1625 C CA . TRP A 1 211 ? -33.235 -22.107 90.812 1.00 30.28 ? 231 TRP A CA 1 ATOM 1626 C C . TRP A 1 211 ? -31.834 -22.320 91.377 1.00 30.42 ? 231 TRP A C 1 ATOM 1627 O O . TRP A 1 211 ? -31.519 -21.844 92.465 1.00 30.42 ? 231 TRP A O 1 ATOM 1628 C CB . TRP A 1 211 ? -33.318 -20.742 90.130 1.00 29.70 ? 231 TRP A CB 1 ATOM 1629 C CG . TRP A 1 211 ? -34.582 -20.514 89.353 1.00 27.93 ? 231 TRP A CG 1 ATOM 1630 C CD1 . TRP A 1 211 ? -35.671 -21.338 89.281 1.00 26.41 ? 231 TRP A CD1 1 ATOM 1631 C CD2 . TRP A 1 211 ? -34.891 -19.377 88.546 1.00 25.82 ? 231 TRP A CD2 1 ATOM 1632 N NE1 . TRP A 1 211 ? -36.631 -20.789 88.470 1.00 25.94 ? 231 TRP A NE1 1 ATOM 1633 C CE2 . TRP A 1 211 ? -36.180 -19.581 88.009 1.00 26.84 ? 231 TRP A CE2 1 ATOM 1634 C CE3 . TRP A 1 211 ? -34.206 -18.202 88.230 1.00 25.71 ? 231 TRP A CE3 1 ATOM 1635 C CZ2 . TRP A 1 211 ? -36.797 -18.653 87.164 1.00 26.38 ? 231 TRP A CZ2 1 ATOM 1636 C CZ3 . TRP A 1 211 ? -34.818 -17.280 87.394 1.00 25.82 ? 231 TRP A CZ3 1 ATOM 1637 C CH2 . TRP A 1 211 ? -36.101 -17.511 86.874 1.00 26.41 ? 231 TRP A CH2 1 ATOM 1638 N N . ALA A 1 212 ? -30.989 -23.029 90.634 1.00 30.28 ? 232 ALA A N 1 ATOM 1639 C CA . ALA A 1 212 ? -29.670 -23.389 91.147 1.00 30.20 ? 232 ALA A CA 1 ATOM 1640 C C . ALA A 1 212 ? -28.613 -23.354 90.065 1.00 30.08 ? 232 ALA A C 1 ATOM 1641 O O . ALA A 1 212 ? -28.864 -23.780 88.938 1.00 30.10 ? 232 ALA A O 1 ATOM 1642 C CB . ALA A 1 212 ? -29.722 -24.791 91.787 1.00 30.09 ? 232 ALA A CB 1 ATOM 1643 N N . VAL A 1 213 ? -27.436 -22.842 90.416 1.00 30.01 ? 233 VAL A N 1 ATOM 1644 C CA . VAL A 1 213 ? -26.246 -23.033 89.604 1.00 30.31 ? 233 VAL A CA 1 ATOM 1645 C C . VAL A 1 213 ? -25.828 -24.481 89.805 1.00 30.54 ? 233 VAL A C 1 ATOM 1646 O O . VAL A 1 213 ? -25.380 -24.844 90.889 1.00 30.89 ? 233 VAL A O 1 ATOM 1647 C CB . VAL A 1 213 ? -25.089 -22.105 90.036 1.00 30.20 ? 233 VAL A CB 1 ATOM 1648 C CG1 . VAL A 1 213 ? -23.817 -22.446 89.277 1.00 29.60 ? 233 VAL A CG1 1 ATOM 1649 C CG2 . VAL A 1 213 ? -25.465 -20.654 89.830 1.00 29.81 ? 233 VAL A CG2 1 ATOM 1650 N N . GLU A 1 214 ? -26.004 -25.315 88.785 1.00 30.50 ? 234 GLU A N 1 ATOM 1651 C CA . GLU A 1 214 ? -25.727 -26.745 88.927 1.00 30.45 ? 234 GLU A CA 1 ATOM 1652 C C . GLU A 1 214 ? -24.329 -27.133 88.466 1.00 30.52 ? 234 GLU A C 1 ATOM 1653 O O . GLU A 1 214 ? -23.878 -28.248 88.727 1.00 30.64 ? 234 GLU A O 1 ATOM 1654 C CB . GLU A 1 214 ? -26.781 -27.587 88.206 1.00 30.50 ? 234 GLU A CB 1 ATOM 1655 C CG . GLU A 1 214 ? -26.901 -27.353 86.710 1.00 30.49 ? 234 GLU A CG 1 ATOM 1656 C CD . GLU A 1 214 ? -27.818 -28.371 86.044 1.00 30.11 ? 234 GLU A CD 1 ATOM 1657 O OE1 . GLU A 1 214 ? -28.885 -27.979 85.499 1.00 30.45 ? 234 GLU A OE1 1 ATOM 1658 O OE2 . GLU A 1 214 ? -27.471 -29.568 86.067 1.00 28.29 ? 234 GLU A OE2 1 ATOM 1659 N N . GLN A 1 215 ? -23.641 -26.223 87.790 1.00 30.50 ? 235 GLN A N 1 ATOM 1660 C CA . GLN A 1 215 ? -22.298 -26.502 87.300 1.00 30.90 ? 235 GLN A CA 1 ATOM 1661 C C . GLN A 1 215 ? -21.578 -25.197 87.009 1.00 29.99 ? 235 GLN A C 1 ATOM 1662 O O . GLN A 1 215 ? -22.209 -24.187 86.728 1.00 29.74 ? 235 GLN A O 1 ATOM 1663 C CB . GLN A 1 215 ? -22.359 -27.381 86.038 1.00 31.53 ? 235 GLN A CB 1 ATOM 1664 C CG . GLN A 1 215 ? -20.996 -27.779 85.432 1.00 33.93 ? 235 GLN A CG 1 ATOM 1665 C CD . GLN A 1 215 ? -20.135 -28.602 86.381 1.00 37.22 ? 235 GLN A CD 1 ATOM 1666 O OE1 . GLN A 1 215 ? -19.146 -28.106 86.931 1.00 41.00 ? 235 GLN A OE1 1 ATOM 1667 N NE2 . GLN A 1 215 ? -20.513 -29.855 86.586 1.00 37.33 ? 235 GLN A NE2 1 ATOM 1668 N N . VAL A 1 216 ? -20.252 -25.252 87.080 1.00 29.22 ? 236 VAL A N 1 ATOM 1669 C CA . VAL A 1 216 ? -19.382 -24.102 86.914 1.00 28.81 ? 236 VAL A CA 1 ATOM 1670 C C . VAL A 1 216 ? -18.196 -24.499 86.038 1.00 28.59 ? 236 VAL A C 1 ATOM 1671 O O . VAL A 1 216 ? -17.541 -25.507 86.291 1.00 28.85 ? 236 VAL A O 1 ATOM 1672 C CB . VAL A 1 216 ? -18.860 -23.641 88.297 1.00 28.89 ? 236 VAL A CB 1 ATOM 1673 C CG1 . VAL A 1 216 ? -17.869 -22.504 88.162 1.00 28.19 ? 236 VAL A CG1 1 ATOM 1674 C CG2 . VAL A 1 216 ? -20.031 -23.251 89.198 1.00 28.71 ? 236 VAL A CG2 1 ATOM 1675 N N . TRP A 1 217 ? -17.923 -23.713 85.007 1.00 28.02 ? 237 TRP A N 1 ATOM 1676 C CA . TRP A 1 217 ? -16.747 -23.921 84.174 1.00 27.60 ? 237 TRP A CA 1 ATOM 1677 C C . TRP A 1 217 ? -15.891 -22.668 84.279 1.00 27.48 ? 237 TRP A C 1 ATOM 1678 O O . TRP A 1 217 ? -16.397 -21.562 84.108 1.00 27.57 ? 237 TRP A O 1 ATOM 1679 C CB . TRP A 1 217 ? -17.171 -24.174 82.723 1.00 27.55 ? 237 TRP A CB 1 ATOM 1680 C CG . TRP A 1 217 ? -16.057 -24.492 81.746 1.00 26.77 ? 237 TRP A CG 1 ATOM 1681 C CD1 . TRP A 1 217 ? -15.657 -25.730 81.343 1.00 26.53 ? 237 TRP A CD1 1 ATOM 1682 C CD2 . TRP A 1 217 ? -15.237 -23.555 81.025 1.00 26.17 ? 237 TRP A CD2 1 ATOM 1683 N NE1 . TRP A 1 217 ? -14.638 -25.630 80.428 1.00 26.17 ? 237 TRP A NE1 1 ATOM 1684 C CE2 . TRP A 1 217 ? -14.364 -24.307 80.209 1.00 25.94 ? 237 TRP A CE2 1 ATOM 1685 C CE3 . TRP A 1 217 ? -15.165 -22.158 80.983 1.00 25.57 ? 237 TRP A CE3 1 ATOM 1686 C CZ2 . TRP A 1 217 ? -13.427 -23.711 79.360 1.00 25.71 ? 237 TRP A CZ2 1 ATOM 1687 C CZ3 . TRP A 1 217 ? -14.224 -21.563 80.139 1.00 26.17 ? 237 TRP A CZ3 1 ATOM 1688 C CH2 . TRP A 1 217 ? -13.364 -22.340 79.347 1.00 25.75 ? 237 TRP A CH2 1 ATOM 1689 N N . TYR A 1 218 ? -14.609 -22.835 84.585 1.00 27.60 ? 238 TYR A N 1 ATOM 1690 C CA . TYR A 1 218 ? -13.676 -21.713 84.575 1.00 27.92 ? 238 TYR A CA 1 ATOM 1691 C C . TYR A 1 218 ? -12.359 -22.099 83.935 1.00 28.33 ? 238 TYR A C 1 ATOM 1692 O O . TYR A 1 218 ? -11.703 -23.041 84.380 1.00 28.30 ? 238 TYR A O 1 ATOM 1693 C CB . TYR A 1 218 ? -13.404 -21.181 85.985 1.00 28.02 ? 238 TYR A CB 1 ATOM 1694 C CG . TYR A 1 218 ? -12.360 -20.096 85.961 1.00 28.08 ? 238 TYR A CG 1 ATOM 1695 C CD1 . TYR A 1 218 ? -12.643 -18.865 85.390 1.00 28.16 ? 238 TYR A CD1 1 ATOM 1696 C CD2 . TYR A 1 218 ? -11.068 -20.316 86.443 1.00 28.72 ? 238 TYR A CD2 1 ATOM 1697 C CE1 . TYR A 1 218 ? -11.694 -17.870 85.327 1.00 27.92 ? 238 TYR A CE1 1 ATOM 1698 C CE2 . TYR A 1 218 ? -10.106 -19.315 86.388 1.00 28.07 ? 238 TYR A CE2 1 ATOM 1699 C CZ . TYR A 1 218 ? -10.431 -18.093 85.822 1.00 27.51 ? 238 TYR A CZ 1 ATOM 1700 O OH . TYR A 1 218 ? -9.509 -17.076 85.742 1.00 26.63 ? 238 TYR A OH 1 ATOM 1701 N N . ASN A 1 219 ? -11.982 -21.372 82.886 1.00 29.00 ? 239 ASN A N 1 ATOM 1702 C CA . ASN A 1 219 ? -10.668 -21.498 82.269 1.00 29.41 ? 239 ASN A CA 1 ATOM 1703 C C . ASN A 1 219 ? -10.238 -22.942 82.034 1.00 29.75 ? 239 ASN A C 1 ATOM 1704 O O . ASN A 1 219 ? -9.115 -23.327 82.364 1.00 29.87 ? 239 ASN A O 1 ATOM 1705 C CB . ASN A 1 219 ? -9.614 -20.781 83.119 1.00 29.66 ? 239 ASN A CB 1 ATOM 1706 C CG . ASN A 1 219 ? -8.264 -20.676 82.416 1.00 30.97 ? 239 ASN A CG 1 ATOM 1707 O OD1 . ASN A 1 219 ? -8.192 -20.682 81.183 1.00 31.55 ? 239 ASN A OD1 1 ATOM 1708 N ND2 . ASN A 1 219 ? -7.187 -20.590 83.199 1.00 31.48 ? 239 ASN A ND2 1 ATOM 1709 N N . GLY A 1 220 ? -11.151 -23.744 81.500 1.00 29.86 ? 240 GLY A N 1 ATOM 1710 C CA . GLY A 1 220 ? -10.821 -25.084 81.017 1.00 30.04 ? 240 GLY A CA 1 ATOM 1711 C C . GLY A 1 220 ? -11.210 -26.231 81.930 1.00 30.25 ? 240 GLY A C 1 ATOM 1712 O O . GLY A 1 220 ? -11.034 -27.388 81.556 1.00 30.20 ? 240 GLY A O 1 ATOM 1713 N N . LYS A 1 221 ? -11.728 -25.932 83.123 1.00 30.50 ? 241 LYS A N 1 ATOM 1714 C CA . LYS A 1 221 ? -12.120 -26.982 84.064 1.00 30.70 ? 241 LYS A CA 1 ATOM 1715 C C . LYS A 1 221 ? -13.522 -26.785 84.617 1.00 30.82 ? 241 LYS A C 1 ATOM 1716 O O . LYS A 1 221 ? -13.989 -25.660 84.789 1.00 30.72 ? 241 LYS A O 1 ATOM 1717 C CB . LYS A 1 221 ? -11.148 -27.050 85.240 1.00 30.81 ? 241 LYS A CB 1 ATOM 1718 C CG . LYS A 1 221 ? -9.742 -27.462 84.878 1.00 31.27 ? 241 LYS A CG 1 ATOM 1719 C CD . LYS A 1 221 ? -8.884 -27.602 86.144 1.00 31.32 ? 241 LYS A CD 1 ATOM 1720 N N . PHE A 1 222 ? -14.170 -27.905 84.913 1.00 31.22 ? 242 PHE A N 1 ATOM 1721 C CA . PHE A 1 222 ? -15.456 -27.912 85.571 1.00 31.51 ? 242 PHE A CA 1 ATOM 1722 C C . PHE A 1 222 ? -15.210 -27.957 87.064 1.00 32.12 ? 242 PHE A C 1 ATOM 1723 O O . PHE A 1 222 ? -14.188 -28.489 87.506 1.00 32.26 ? 242 PHE A O 1 ATOM 1724 C CB . PHE A 1 222 ? -16.272 -29.113 85.117 1.00 31.36 ? 242 PHE A CB 1 ATOM 1725 C CG . PHE A 1 222 ? -16.706 -29.037 83.686 1.00 31.61 ? 242 PHE A CG 1 ATOM 1726 C CD1 . PHE A 1 222 ? -17.855 -28.343 83.332 1.00 31.37 ? 242 PHE A CD1 1 ATOM 1727 C CD2 . PHE A 1 222 ? -15.968 -29.663 82.688 1.00 32.47 ? 242 PHE A CD2 1 ATOM 1728 C CE1 . PHE A 1 222 ? -18.267 -28.268 82.001 1.00 31.52 ? 242 PHE A CE1 1 ATOM 1729 C CE2 . PHE A 1 222 ? -16.372 -29.596 81.357 1.00 32.47 ? 242 PHE A CE2 1 ATOM 1730 C CZ . PHE A 1 222 ? -17.523 -28.891 81.013 1.00 31.98 ? 242 PHE A CZ 1 ATOM 1731 N N . TYR A 1 223 ? -16.133 -27.388 87.837 1.00 32.74 ? 243 TYR A N 1 ATOM 1732 C CA . TYR A 1 223 ? -15.945 -27.274 89.287 1.00 33.09 ? 243 TYR A CA 1 ATOM 1733 C C . TYR A 1 223 ? -17.139 -27.668 90.144 1.00 33.63 ? 243 TYR A C 1 ATOM 1734 O O . TYR A 1 223 ? -17.022 -27.682 91.369 1.00 34.96 ? 243 TYR A O 1 ATOM 1735 C CB . TYR A 1 223 ? -15.525 -25.847 89.646 1.00 32.95 ? 243 TYR A CB 1 ATOM 1736 C CG . TYR A 1 223 ? -14.096 -25.561 89.309 1.00 32.49 ? 243 TYR A CG 1 ATOM 1737 C CD1 . TYR A 1 223 ? -13.760 -24.866 88.154 1.00 32.24 ? 243 TYR A CD1 1 ATOM 1738 C CD2 . TYR A 1 223 ? -13.071 -26.005 90.130 1.00 31.60 ? 243 TYR A CD2 1 ATOM 1739 C CE1 . TYR A 1 223 ? -12.443 -24.607 87.835 1.00 31.40 ? 243 TYR A CE1 1 ATOM 1740 C CE2 . TYR A 1 223 ? -11.748 -25.753 89.815 1.00 31.42 ? 243 TYR A CE2 1 ATOM 1741 C CZ . TYR A 1 223 ? -11.441 -25.055 88.669 1.00 31.24 ? 243 TYR A CZ 1 ATOM 1742 O OH . TYR A 1 223 ? -10.127 -24.801 88.352 1.00 32.91 ? 243 TYR A OH 1 ATOM 1743 N N . GLY A 1 224 ? -18.289 -27.957 89.551 1.00 33.55 ? 244 GLY A N 1 ATOM 1744 C CA . GLY A 1 224 ? -19.413 -28.473 90.344 1.00 33.69 ? 244 GLY A CA 1 ATOM 1745 C C . GLY A 1 224 ? -20.274 -27.406 91.002 1.00 33.51 ? 244 GLY A C 1 ATOM 1746 O O . GLY A 1 224 ? -21.487 -27.398 90.812 1.00 34.02 ? 244 GLY A O 1 ATOM 1747 N N . SER A 1 225 ? -19.655 -26.518 91.781 1.00 33.35 ? 245 SER A N 1 ATOM 1748 C CA . SER A 1 225 ? -20.369 -25.424 92.455 1.00 33.06 ? 245 SER A CA 1 ATOM 1749 C C . SER A 1 225 ? -19.507 -24.163 92.557 1.00 33.01 ? 245 SER A C 1 ATOM 1750 O O . SER A 1 225 ? -18.286 -24.239 92.458 1.00 32.69 ? 245 SER A O 1 ATOM 1751 C CB . SER A 1 225 ? -20.764 -25.846 93.875 1.00 33.13 ? 245 SER A CB 1 ATOM 1752 O OG . SER A 1 225 ? -19.644 -25.776 94.758 1.00 33.11 ? 245 SER A OG 1 ATOM 1753 N N . PRO A 1 226 ? -20.145 -22.997 92.780 1.00 33.01 ? 246 PRO A N 1 ATOM 1754 C CA . PRO A 1 226 ? -19.385 -21.786 93.097 1.00 33.08 ? 246 PRO A CA 1 ATOM 1755 C C . PRO A 1 226 ? -18.465 -21.944 94.320 1.00 33.23 ? 246 PRO A C 1 ATOM 1756 O O . PRO A 1 226 ? -17.316 -21.486 94.292 1.00 33.12 ? 246 PRO A O 1 ATOM 1757 C CB . PRO A 1 226 ? -20.476 -20.751 93.373 1.00 33.22 ? 246 PRO A CB 1 ATOM 1758 C CG . PRO A 1 226 ? -21.671 -21.238 92.610 1.00 33.32 ? 246 PRO A CG 1 ATOM 1759 C CD . PRO A 1 226 ? -21.580 -22.725 92.570 1.00 32.89 ? 246 PRO A CD 1 ATOM 1760 N N . GLU A 1 227 ? -18.964 -22.602 95.366 1.00 33.32 ? 247 GLU A N 1 ATOM 1761 C CA . GLU A 1 227 ? -18.187 -22.819 96.595 1.00 33.63 ? 247 GLU A CA 1 ATOM 1762 C C . GLU A 1 227 ? -16.905 -23.611 96.339 1.00 33.64 ? 247 GLU A C 1 ATOM 1763 O O . GLU A 1 227 ? -15.839 -23.264 96.861 1.00 33.84 ? 247 GLU A O 1 ATOM 1764 C CB . GLU A 1 227 ? -19.039 -23.527 97.660 1.00 33.60 ? 247 GLU A CB 1 ATOM 1765 N N . GLU A 1 228 ? -16.999 -24.655 95.520 1.00 33.68 ? 248 GLU A N 1 ATOM 1766 C CA . GLU A 1 228 ? -15.835 -25.480 95.199 1.00 33.88 ? 248 GLU A CA 1 ATOM 1767 C C . GLU A 1 228 ? -14.764 -24.669 94.476 1.00 34.08 ? 248 GLU A C 1 ATOM 1768 O O . GLU A 1 228 ? -13.583 -24.764 94.809 1.00 34.38 ? 248 GLU A O 1 ATOM 1769 C CB . GLU A 1 228 ? -16.242 -26.696 94.363 1.00 33.74 ? 248 GLU A CB 1 ATOM 1770 C CG . GLU A 1 228 ? -15.087 -27.608 93.957 0.50 33.73 ? 248 GLU A CG 1 ATOM 1771 C CD . GLU A 1 228 ? -15.547 -28.850 93.211 0.50 33.65 ? 248 GLU A CD 1 ATOM 1772 O OE1 . GLU A 1 228 ? -16.614 -29.402 93.554 0.50 33.75 ? 248 GLU A OE1 1 ATOM 1773 O OE2 . GLU A 1 228 ? -14.843 -29.272 92.274 0.50 33.35 ? 248 GLU A OE2 1 ATOM 1774 N N . LEU A 1 229 ? -15.163 -23.874 93.485 1.00 34.20 ? 249 LEU A N 1 ATOM 1775 C CA . LEU A 1 229 ? -14.197 -22.996 92.797 1.00 34.08 ? 249 LEU A CA 1 ATOM 1776 C C . LEU A 1 229 ? -13.593 -21.982 93.792 1.00 34.20 ? 249 LEU A C 1 ATOM 1777 O O . LEU A 1 229 ? -12.382 -21.747 93.796 1.00 33.97 ? 249 LEU A O 1 ATOM 1778 C CB . LEU A 1 229 ? -14.861 -22.276 91.615 1.00 33.71 ? 249 LEU A CB 1 ATOM 1779 C CG . LEU A 1 229 ? -14.021 -21.270 90.824 1.00 33.86 ? 249 LEU A CG 1 ATOM 1780 C CD1 . LEU A 1 229 ? -12.704 -21.898 90.311 1.00 32.22 ? 249 LEU A CD1 1 ATOM 1781 C CD2 . LEU A 1 229 ? -14.846 -20.678 89.665 1.00 32.84 ? 249 LEU A CD2 1 ATOM 1782 N N . ALA A 1 230 ? -14.446 -21.397 94.628 1.00 34.22 ? 250 ALA A N 1 ATOM 1783 C CA . ALA A 1 230 ? -13.999 -20.474 95.674 1.00 34.82 ? 250 ALA A CA 1 ATOM 1784 C C . ALA A 1 230 ? -12.946 -21.132 96.573 1.00 35.25 ? 250 ALA A C 1 ATOM 1785 O O . ALA A 1 230 ? -11.870 -20.575 96.803 1.00 35.50 ? 250 ALA A O 1 ATOM 1786 C CB . ALA A 1 230 ? -15.183 -20.015 96.501 1.00 34.35 ? 250 ALA A CB 1 ATOM 1787 N N . ARG A 1 231 ? -13.263 -22.329 97.056 1.00 35.91 ? 251 ARG A N 1 ATOM 1788 C CA . ARG A 1 231 ? -12.351 -23.099 97.902 1.00 36.28 ? 251 ARG A CA 1 ATOM 1789 C C . ARG A 1 231 ? -11.009 -23.318 97.208 1.00 36.78 ? 251 ARG A C 1 ATOM 1790 O O . ARG A 1 231 ? -9.954 -22.890 97.716 1.00 37.00 ? 251 ARG A O 1 ATOM 1791 C CB . ARG A 1 231 ? -12.976 -24.450 98.260 1.00 36.12 ? 251 ARG A CB 1 ATOM 1792 N N . LYS A 1 232 ? -11.056 -23.976 96.049 1.00 36.89 ? 252 LYS A N 1 ATOM 1793 C CA . LYS A 1 232 ? -9.844 -24.320 95.301 1.00 37.15 ? 252 LYS A CA 1 ATOM 1794 C C . LYS A 1 232 ? -9.025 -23.086 94.947 1.00 37.35 ? 252 LYS A C 1 ATOM 1795 O O . LYS A 1 232 ? -7.793 -23.132 94.950 1.00 37.55 ? 252 LYS A O 1 ATOM 1796 C CB . LYS A 1 232 ? -10.182 -25.110 94.036 1.00 37.31 ? 252 LYS A CB 1 ATOM 1797 C CG . LYS A 1 232 ? -10.653 -26.533 94.310 1.00 37.74 ? 252 LYS A CG 1 ATOM 1798 C CD . LYS A 1 232 ? -10.754 -27.355 93.033 1.00 38.33 ? 252 LYS A CD 1 ATOM 1799 N N . TYR A 1 233 ? -9.704 -21.983 94.654 1.00 37.44 ? 253 TYR A N 1 ATOM 1800 C CA . TYR A 1 233 ? -9.016 -20.717 94.439 1.00 37.68 ? 253 TYR A CA 1 ATOM 1801 C C . TYR A 1 233 ? -8.347 -20.218 95.714 1.00 38.11 ? 253 TYR A C 1 ATOM 1802 O O . TYR A 1 233 ? -7.196 -19.787 95.678 1.00 38.17 ? 253 TYR A O 1 ATOM 1803 C CB . TYR A 1 233 ? -9.974 -19.647 93.938 1.00 37.41 ? 253 TYR A CB 1 ATOM 1804 C CG . TYR A 1 233 ? -9.343 -18.280 93.875 1.00 36.75 ? 253 TYR A CG 1 ATOM 1805 C CD1 . TYR A 1 233 ? -8.265 -18.033 93.036 1.00 36.15 ? 253 TYR A CD1 1 ATOM 1806 C CD2 . TYR A 1 233 ? -9.818 -17.235 94.660 1.00 36.39 ? 253 TYR A CD2 1 ATOM 1807 C CE1 . TYR A 1 233 ? -7.683 -16.777 92.967 1.00 36.43 ? 253 TYR A CE1 1 ATOM 1808 C CE2 . TYR A 1 233 ? -9.239 -15.978 94.604 1.00 36.80 ? 253 TYR A CE2 1 ATOM 1809 C CZ . TYR A 1 233 ? -8.173 -15.756 93.756 1.00 36.94 ? 253 TYR A CZ 1 ATOM 1810 O OH . TYR A 1 233 ? -7.599 -14.508 93.697 1.00 38.46 ? 253 TYR A OH 1 ATOM 1811 N N . ALA A 1 234 ? -9.081 -20.245 96.823 1.00 38.73 ? 254 ALA A N 1 ATOM 1812 C CA . ALA A 1 234 ? -8.533 -19.834 98.117 1.00 39.45 ? 254 ALA A CA 1 ATOM 1813 C C . ALA A 1 234 ? -7.291 -20.668 98.444 1.00 39.99 ? 254 ALA A C 1 ATOM 1814 O O . ALA A 1 234 ? -6.265 -20.124 98.842 1.00 40.06 ? 254 ALA A O 1 ATOM 1815 C CB . ALA A 1 234 ? -9.585 -19.964 99.222 1.00 39.16 ? 254 ALA A CB 1 ATOM 1816 N N . ASP A 1 235 ? -7.373 -21.976 98.208 1.00 40.80 ? 255 ASP A N 1 ATOM 1817 C CA . ASP A 1 235 ? -6.258 -22.898 98.463 1.00 41.50 ? 255 ASP A CA 1 ATOM 1818 C C . ASP A 1 235 ? -5.170 -22.887 97.379 1.00 41.77 ? 255 ASP A C 1 ATOM 1819 O O . ASP A 1 235 ? -4.334 -23.799 97.327 1.00 41.97 ? 255 ASP A O 1 ATOM 1820 C CB . ASP A 1 235 ? -6.783 -24.339 98.629 1.00 41.73 ? 255 ASP A CB 1 ATOM 1821 C CG . ASP A 1 235 ? -7.730 -24.487 99.794 1.00 42.11 ? 255 ASP A CG 1 ATOM 1822 O OD1 . ASP A 1 235 ? -7.783 -23.573 100.641 1.00 44.43 ? 255 ASP A OD1 1 ATOM 1823 O OD2 . ASP A 1 235 ? -8.423 -25.519 99.867 1.00 43.12 ? 255 ASP A OD2 1 ATOM 1824 N N . GLY A 1 236 ? -5.179 -21.881 96.506 1.00 41.98 ? 256 GLY A N 1 ATOM 1825 C CA . GLY A 1 236 ? -4.118 -21.725 95.511 1.00 42.06 ? 256 GLY A CA 1 ATOM 1826 C C . GLY A 1 236 ? -4.025 -22.838 94.474 1.00 42.19 ? 256 GLY A C 1 ATOM 1827 O O . GLY A 1 236 ? -2.977 -23.009 93.843 1.00 42.23 ? 256 GLY A O 1 ATOM 1828 N N . GLU A 1 237 ? -5.119 -23.578 94.281 1.00 42.29 ? 257 GLU A N 1 ATOM 1829 C CA . GLU A 1 237 ? -5.149 -24.717 93.354 1.00 42.37 ? 257 GLU A CA 1 ATOM 1830 C C . GLU A 1 237 ? -5.783 -24.385 91.996 1.00 41.87 ? 257 GLU A C 1 ATOM 1831 O O . GLU A 1 237 ? -6.084 -25.296 91.229 1.00 41.74 ? 257 GLU A O 1 ATOM 1832 C CB . GLU A 1 237 ? -5.930 -25.891 93.957 1.00 42.72 ? 257 GLU A CB 1 ATOM 1833 C CG . GLU A 1 237 ? -5.517 -26.310 95.348 1.00 44.49 ? 257 GLU A CG 1 ATOM 1834 C CD . GLU A 1 237 ? -6.208 -27.594 95.781 1.00 47.10 ? 257 GLU A CD 1 ATOM 1835 O OE1 . GLU A 1 237 ? -6.015 -28.624 95.095 1.00 50.10 ? 257 GLU A OE1 1 ATOM 1836 O OE2 . GLU A 1 237 ? -6.943 -27.579 96.796 1.00 48.50 ? 257 GLU A OE2 1 ATOM 1837 N N . VAL A 1 238 ? -6.002 -23.105 91.698 1.00 41.35 ? 258 VAL A N 1 ATOM 1838 C CA . VAL A 1 238 ? -6.609 -22.720 90.418 1.00 40.71 ? 258 VAL A CA 1 ATOM 1839 C C . VAL A 1 238 ? -5.676 -21.833 89.612 1.00 40.30 ? 258 VAL A C 1 ATOM 1840 O O . VAL A 1 238 ? -5.289 -20.766 90.073 1.00 40.17 ? 258 VAL A O 1 ATOM 1841 C CB . VAL A 1 238 ? -7.944 -21.977 90.615 1.00 40.61 ? 258 VAL A CB 1 ATOM 1842 C CG1 . VAL A 1 238 ? -8.533 -21.563 89.259 1.00 40.48 ? 258 VAL A CG1 1 ATOM 1843 C CG2 . VAL A 1 238 ? -8.920 -22.845 91.387 1.00 39.75 ? 258 VAL A CG2 1 ATOM 1844 N N . ASP A 1 239 ? -5.325 -22.282 88.409 1.00 39.87 ? 259 ASP A N 1 ATOM 1845 C CA . ASP A 1 239 ? -4.595 -21.452 87.463 1.00 39.90 ? 259 ASP A CA 1 ATOM 1846 C C . ASP A 1 239 ? -5.562 -20.418 86.904 1.00 39.71 ? 259 ASP A C 1 ATOM 1847 O O . ASP A 1 239 ? -6.354 -20.719 86.013 1.00 39.98 ? 259 ASP A O 1 ATOM 1848 C CB . ASP A 1 239 ? -3.996 -22.299 86.333 1.00 39.98 ? 259 ASP A CB 1 ATOM 1849 N N . VAL A 1 240 ? -5.510 -19.206 87.445 1.00 39.51 ? 260 VAL A N 1 ATOM 1850 C CA . VAL A 1 240 ? -6.435 -18.154 87.046 1.00 39.39 ? 260 VAL A CA 1 ATOM 1851 C C . VAL A 1 240 ? -5.803 -17.224 86.015 1.00 39.46 ? 260 VAL A C 1 ATOM 1852 O O . VAL A 1 240 ? -4.575 -17.144 85.887 1.00 39.01 ? 260 VAL A O 1 ATOM 1853 C CB . VAL A 1 240 ? -6.919 -17.320 88.256 1.00 39.52 ? 260 VAL A CB 1 ATOM 1854 C CG1 . VAL A 1 240 ? -7.509 -18.232 89.340 1.00 39.57 ? 260 VAL A CG1 1 ATOM 1855 C CG2 . VAL A 1 240 ? -5.791 -16.458 88.822 1.00 39.23 ? 260 VAL A CG2 1 ATOM 1856 N N . VAL A 1 241 ? -6.663 -16.539 85.268 1.00 39.26 ? 261 VAL A N 1 ATOM 1857 C CA . VAL A 1 241 ? -6.229 -15.494 84.360 1.00 39.16 ? 261 VAL A CA 1 ATOM 1858 C C . VAL A 1 241 ? -6.730 -14.177 84.926 1.00 39.27 ? 261 VAL A C 1 ATOM 1859 O O . VAL A 1 241 ? -7.937 -13.924 84.940 1.00 39.08 ? 261 VAL A O 1 ATOM 1860 C CB . VAL A 1 241 ? -6.784 -15.700 82.944 1.00 39.13 ? 261 VAL A CB 1 ATOM 1861 C CG1 . VAL A 1 241 ? -6.267 -14.612 82.010 1.00 38.03 ? 261 VAL A CG1 1 ATOM 1862 C CG2 . VAL A 1 241 ? -6.412 -17.082 82.428 1.00 38.82 ? 261 VAL A CG2 1 ATOM 1863 N N . VAL A 1 242 ? -5.799 -13.363 85.413 1.00 39.41 ? 262 VAL A N 1 ATOM 1864 C CA . VAL A 1 242 ? -6.101 -12.034 85.928 1.00 39.77 ? 262 VAL A CA 1 ATOM 1865 C C . VAL A 1 242 ? -6.209 -11.062 84.751 1.00 40.48 ? 262 VAL A C 1 ATOM 1866 O O . VAL A 1 242 ? -5.229 -10.820 84.044 1.00 40.34 ? 262 VAL A O 1 ATOM 1867 C CB . VAL A 1 242 ? -5.002 -11.546 86.904 1.00 39.80 ? 262 VAL A CB 1 ATOM 1868 C CG1 . VAL A 1 242 ? -5.298 -10.127 87.383 1.00 39.62 ? 262 VAL A CG1 1 ATOM 1869 C CG2 . VAL A 1 242 ? -4.862 -12.509 88.087 1.00 38.86 ? 262 VAL A CG2 1 ATOM 1870 N N . LEU A 1 243 ? -7.403 -10.516 84.541 1.00 41.29 ? 263 LEU A N 1 ATOM 1871 C CA . LEU A 1 243 ? -7.657 -9.609 83.419 1.00 41.99 ? 263 LEU A CA 1 ATOM 1872 C C . LEU A 1 243 ? -7.159 -8.211 83.767 1.00 43.12 ? 263 LEU A C 1 ATOM 1873 O O . LEU A 1 243 ? -7.288 -7.777 84.917 1.00 43.23 ? 263 LEU A O 1 ATOM 1874 C CB . LEU A 1 243 ? -9.156 -9.543 83.115 1.00 41.66 ? 263 LEU A CB 1 ATOM 1875 C CG . LEU A 1 243 ? -9.892 -10.869 82.964 1.00 41.07 ? 263 LEU A CG 1 ATOM 1876 C CD1 . LEU A 1 243 ? -11.367 -10.620 82.762 1.00 40.31 ? 263 LEU A CD1 1 ATOM 1877 C CD2 . LEU A 1 243 ? -9.308 -11.680 81.822 1.00 40.42 ? 263 LEU A CD2 1 ATOM 1878 N N . GLU A 1 244 ? -6.616 -7.502 82.780 1.00 44.46 ? 264 GLU A N 1 ATOM 1879 C CA . GLU A 1 244 ? -6.165 -6.118 82.989 1.00 45.56 ? 264 GLU A CA 1 ATOM 1880 C C . GLU A 1 244 ? -7.358 -5.179 83.190 1.00 46.65 ? 264 GLU A C 1 ATOM 1881 O O . GLU A 1 244 ? -8.509 -5.559 82.953 1.00 46.60 ? 264 GLU A O 1 ATOM 1882 C CB . GLU A 1 244 ? -5.304 -5.634 81.818 1.00 45.42 ? 264 GLU A CB 1 ATOM 1883 N N . ASP A 1 245 ? -7.068 -3.962 83.644 1.00 47.90 ? 265 ASP A N 1 ATOM 1884 C CA . ASP A 1 245 ? -8.090 -2.941 83.871 1.00 49.05 ? 265 ASP A CA 1 ATOM 1885 C C . ASP A 1 245 ? -8.570 -2.429 82.514 1.00 49.71 ? 265 ASP A C 1 ATOM 1886 O O . ASP A 1 245 ? -7.748 -2.048 81.683 1.00 50.05 ? 265 ASP A O 1 ATOM 1887 C CB . ASP A 1 245 ? -7.498 -1.788 84.705 1.00 49.22 ? 265 ASP A CB 1 ATOM 1888 C CG . ASP A 1 245 ? -8.548 -0.784 85.193 1.00 50.01 ? 265 ASP A CG 1 ATOM 1889 O OD1 . ASP A 1 245 ? -9.663 -0.708 84.634 1.00 51.29 ? 265 ASP A OD1 1 ATOM 1890 O OD2 . ASP A 1 245 ? -8.247 -0.042 86.151 1.00 51.78 ? 265 ASP A OD2 1 ATOM 1891 N N . PRO A 1 246 ? -9.894 -2.446 82.270 1.00 50.49 ? 266 PRO A N 1 ATOM 1892 C CA . PRO A 1 246 ? -10.430 -1.832 81.054 1.00 51.00 ? 266 PRO A CA 1 ATOM 1893 C C . PRO A 1 246 ? -10.719 -0.342 81.227 1.00 51.61 ? 266 PRO A C 1 ATOM 1894 O O . PRO A 1 246 ? -10.417 0.441 80.325 1.00 52.28 ? 266 PRO A O 1 ATOM 1895 C CB . PRO A 1 246 ? -11.727 -2.611 80.805 1.00 50.92 ? 266 PRO A CB 1 ATOM 1896 C CG . PRO A 1 246 ? -12.159 -3.078 82.139 1.00 50.46 ? 266 PRO A CG 1 ATOM 1897 C CD . PRO A 1 246 ? -10.937 -3.167 83.024 1.00 50.55 ? 266 PRO A CD 1 ATOM 1898 N N . LEU A 1 247 ? -11.294 0.038 82.371 1.00 52.06 ? 267 LEU A N 1 ATOM 1899 C CA . LEU A 1 247 ? -11.661 1.427 82.653 1.00 52.14 ? 267 LEU A CA 1 ATOM 1900 C C . LEU A 1 247 ? -10.532 2.135 83.401 1.00 52.42 ? 267 LEU A C 1 ATOM 1901 O O . LEU A 1 247 ? -9.473 2.405 82.831 1.00 52.69 ? 267 LEU A O 1 ATOM 1902 C CB . LEU A 1 247 ? -12.938 1.480 83.495 1.00 52.25 ? 267 LEU A CB 1 ATOM 1903 C CG . LEU A 1 247 ? -14.147 0.683 82.993 1.00 52.19 ? 267 LEU A CG 1 ATOM 1904 C CD1 . LEU A 1 247 ? -15.277 0.762 84.003 1.00 51.98 ? 267 LEU A CD1 1 ATOM 1905 C CD2 . LEU A 1 247 ? -14.599 1.175 81.622 1.00 52.05 ? 267 LEU A CD2 1 ATOM 1906 N N . GLU A 1 258 ? -6.616 6.716 77.372 1.00 39.27 ? 278 GLU A N 1 ATOM 1907 C CA . GLU A 1 258 ? -6.719 7.588 76.210 1.00 39.04 ? 278 GLU A CA 1 ATOM 1908 C C . GLU A 1 258 ? -7.188 6.821 74.969 1.00 38.73 ? 278 GLU A C 1 ATOM 1909 O O . GLU A 1 258 ? -8.172 7.220 74.338 1.00 39.30 ? 278 GLU A O 1 ATOM 1910 C CB . GLU A 1 258 ? -5.380 8.285 75.933 1.00 39.10 ? 278 GLU A CB 1 ATOM 1911 N N . PRO A 1 259 ? -6.498 5.719 74.609 1.00 37.91 ? 279 PRO A N 1 ATOM 1912 C CA . PRO A 1 259 ? -6.926 5.004 73.393 1.00 37.07 ? 279 PRO A CA 1 ATOM 1913 C C . PRO A 1 259 ? -8.328 4.410 73.522 1.00 36.05 ? 279 PRO A C 1 ATOM 1914 O O . PRO A 1 259 ? -8.750 4.081 74.628 1.00 36.22 ? 279 PRO A O 1 ATOM 1915 C CB . PRO A 1 259 ? -5.892 3.878 73.244 1.00 37.20 ? 279 PRO A CB 1 ATOM 1916 C CG . PRO A 1 259 ? -4.754 4.243 74.149 1.00 37.74 ? 279 PRO A CG 1 ATOM 1917 C CD . PRO A 1 259 ? -5.344 5.066 75.255 1.00 38.15 ? 279 PRO A CD 1 ATOM 1918 N N . PRO A 1 260 ? -9.053 4.270 72.401 1.00 34.61 ? 280 PRO A N 1 ATOM 1919 C CA . PRO A 1 260 ? -10.338 3.577 72.487 1.00 33.63 ? 280 PRO A CA 1 ATOM 1920 C C . PRO A 1 260 ? -10.201 2.125 72.946 1.00 32.35 ? 280 PRO A C 1 ATOM 1921 O O . PRO A 1 260 ? -9.177 1.490 72.711 1.00 31.78 ? 280 PRO A O 1 ATOM 1922 C CB . PRO A 1 260 ? -10.863 3.625 71.044 1.00 33.76 ? 280 PRO A CB 1 ATOM 1923 C CG . PRO A 1 260 ? -10.173 4.775 70.422 1.00 34.12 ? 280 PRO A CG 1 ATOM 1924 C CD . PRO A 1 260 ? -8.805 4.790 71.044 1.00 34.59 ? 280 PRO A CD 1 ATOM 1925 N N . LEU A 1 261 ? -11.234 1.622 73.608 1.00 31.21 ? 281 LEU A N 1 ATOM 1926 C CA . LEU A 1 261 ? -11.324 0.208 73.947 1.00 30.59 ? 281 LEU A CA 1 ATOM 1927 C C . LEU A 1 261 ? -11.413 -0.579 72.639 1.00 29.89 ? 281 LEU A C 1 ATOM 1928 O O . LEU A 1 261 ? -12.082 -0.140 71.696 1.00 29.36 ? 281 LEU A O 1 ATOM 1929 C CB . LEU A 1 261 ? -12.569 -0.034 74.814 1.00 30.48 ? 281 LEU A CB 1 ATOM 1930 C CG . LEU A 1 261 ? -12.584 -1.198 75.798 1.00 31.16 ? 281 LEU A CG 1 ATOM 1931 C CD1 . LEU A 1 261 ? -11.367 -1.182 76.709 1.00 30.65 ? 281 LEU A CD1 1 ATOM 1932 C CD2 . LEU A 1 261 ? -13.885 -1.152 76.625 1.00 31.57 ? 281 LEU A CD2 1 ATOM 1933 N N . PHE A 1 262 ? -10.729 -1.719 72.559 1.00 29.07 ? 282 PHE A N 1 ATOM 1934 C CA . PHE A 1 262 ? -10.736 -2.512 71.322 1.00 28.61 ? 282 PHE A CA 1 ATOM 1935 C C . PHE A 1 262 ? -12.161 -2.823 70.849 1.00 27.75 ? 282 PHE A C 1 ATOM 1936 O O . PHE A 1 262 ? -12.383 -2.980 69.655 1.00 27.58 ? 282 PHE A O 1 ATOM 1937 C CB . PHE A 1 262 ? -9.902 -3.802 71.454 1.00 28.61 ? 282 PHE A CB 1 ATOM 1938 C CG . PHE A 1 262 ? -10.572 -4.904 72.250 1.00 29.70 ? 282 PHE A CG 1 ATOM 1939 C CD1 . PHE A 1 262 ? -11.429 -5.805 71.632 1.00 29.90 ? 282 PHE A CD1 1 ATOM 1940 C CD2 . PHE A 1 262 ? -10.316 -5.062 73.605 1.00 29.64 ? 282 PHE A CD2 1 ATOM 1941 C CE1 . PHE A 1 262 ? -12.041 -6.818 72.358 1.00 29.43 ? 282 PHE A CE1 1 ATOM 1942 C CE2 . PHE A 1 262 ? -10.920 -6.079 74.328 1.00 29.46 ? 282 PHE A CE2 1 ATOM 1943 C CZ . PHE A 1 262 ? -11.783 -6.950 73.707 1.00 29.61 ? 282 PHE A CZ 1 ATOM 1944 N N . SER A 1 263 ? -13.117 -2.885 71.779 1.00 26.70 ? 283 SER A N 1 ATOM 1945 C CA . SER A 1 263 ? -14.511 -3.210 71.456 1.00 25.93 ? 283 SER A CA 1 ATOM 1946 C C . SER A 1 263 ? -15.384 -1.988 71.171 1.00 25.45 ? 283 SER A C 1 ATOM 1947 O O . SER A 1 263 ? -16.605 -2.121 71.038 1.00 25.04 ? 283 SER A O 1 ATOM 1948 C CB . SER A 1 263 ? -15.135 -4.025 72.590 1.00 26.00 ? 283 SER A CB 1 ATOM 1949 O OG . SER A 1 263 ? -15.076 -3.317 73.809 1.00 25.72 ? 283 SER A OG 1 ATOM 1950 N N . SER A 1 264 ? -14.755 -0.815 71.091 1.00 25.09 ? 284 SER A N 1 ATOM 1951 C CA A SER A 1 264 ? -15.426 0.432 70.741 0.50 24.83 ? 284 SER A CA 1 ATOM 1952 C CA B SER A 1 264 ? -15.439 0.428 70.738 0.50 25.25 ? 284 SER A CA 1 ATOM 1953 C C . SER A 1 264 ? -15.384 0.673 69.234 1.00 25.24 ? 284 SER A C 1 ATOM 1954 O O . SER A 1 264 ? -14.457 0.232 68.562 1.00 25.26 ? 284 SER A O 1 ATOM 1955 C CB A SER A 1 264 ? -14.745 1.609 71.446 0.50 24.68 ? 284 SER A CB 1 ATOM 1956 C CB B SER A 1 264 ? -14.814 1.627 71.466 0.50 25.17 ? 284 SER A CB 1 ATOM 1957 O OG A SER A 1 264 ? -15.328 2.840 71.070 0.50 22.41 ? 284 SER A OG 1 ATOM 1958 O OG B SER A 1 264 ? -13.528 1.940 70.961 0.50 25.49 ? 284 SER A OG 1 ATOM 1959 N N . HIS A 1 265 ? -16.379 1.398 68.718 1.00 25.77 ? 285 HIS A N 1 ATOM 1960 C CA . HIS A 1 265 ? -16.379 1.827 67.319 1.00 26.33 ? 285 HIS A CA 1 ATOM 1961 C C . HIS A 1 265 ? -15.551 3.108 67.107 1.00 27.10 ? 285 HIS A C 1 ATOM 1962 O O . HIS A 1 265 ? -15.398 3.557 65.974 1.00 27.09 ? 285 HIS A O 1 ATOM 1963 C CB . HIS A 1 265 ? -17.804 2.086 66.818 1.00 26.29 ? 285 HIS A CB 1 ATOM 1964 C CG . HIS A 1 265 ? -18.565 0.847 66.464 1.00 26.09 ? 285 HIS A CG 1 ATOM 1965 N ND1 . HIS A 1 265 ? -19.081 -0.006 67.414 1.00 26.56 ? 285 HIS A ND1 1 ATOM 1966 C CD2 . HIS A 1 265 ? -18.942 0.346 65.266 1.00 26.01 ? 285 HIS A CD2 1 ATOM 1967 C CE1 . HIS A 1 265 ? -19.725 -0.991 66.816 1.00 25.88 ? 285 HIS A CE1 1 ATOM 1968 N NE2 . HIS A 1 265 ? -19.660 -0.797 65.514 1.00 26.07 ? 285 HIS A NE2 1 ATOM 1969 N N . LYS A 1 266 ? -15.033 3.704 68.178 1.00 27.64 ? 286 LYS A N 1 ATOM 1970 C CA . LYS A 1 266 ? -14.313 4.973 68.060 1.00 28.55 ? 286 LYS A CA 1 ATOM 1971 C C . LYS A 1 266 ? -13.110 4.852 67.114 1.00 28.60 ? 286 LYS A C 1 ATOM 1972 O O . LYS A 1 266 ? -12.363 3.880 67.184 1.00 28.66 ? 286 LYS A O 1 ATOM 1973 C CB . LYS A 1 266 ? -13.841 5.453 69.428 1.00 28.84 ? 286 LYS A CB 1 ATOM 1974 C CG . LYS A 1 266 ? -14.952 5.963 70.321 1.00 30.60 ? 286 LYS A CG 1 ATOM 1975 C CD . LYS A 1 266 ? -14.431 6.222 71.736 1.00 33.19 ? 286 LYS A CD 1 ATOM 1976 C CE . LYS A 1 266 ? -15.475 6.915 72.608 1.00 34.53 ? 286 LYS A CE 1 ATOM 1977 N NZ . LYS A 1 266 ? -15.050 6.949 74.045 1.00 36.53 ? 286 LYS A NZ 1 ATOM 1978 N N . PRO A 1 267 ? -12.927 5.832 66.214 1.00 28.75 ? 287 PRO A N 1 ATOM 1979 C CA . PRO A 1 267 ? -11.808 5.713 65.273 1.00 28.96 ? 287 PRO A CA 1 ATOM 1980 C C . PRO A 1 267 ? -10.434 5.659 65.935 1.00 29.02 ? 287 PRO A C 1 ATOM 1981 O O . PRO A 1 267 ? -10.205 6.314 66.950 1.00 29.29 ? 287 PRO A O 1 ATOM 1982 C CB . PRO A 1 267 ? -11.932 6.974 64.414 1.00 29.23 ? 287 PRO A CB 1 ATOM 1983 C CG . PRO A 1 267 ? -13.347 7.371 64.508 1.00 29.08 ? 287 PRO A CG 1 ATOM 1984 C CD . PRO A 1 267 ? -13.816 6.954 65.871 1.00 28.72 ? 287 PRO A CD 1 ATOM 1985 N N . ARG A 1 268 ? -9.547 4.850 65.374 1.00 29.05 ? 288 ARG A N 1 ATOM 1986 C CA . ARG A 1 268 ? -8.130 4.890 65.708 1.00 29.06 ? 288 ARG A CA 1 ATOM 1987 C C . ARG A 1 268 ? -7.334 4.448 64.495 1.00 29.74 ? 288 ARG A C 1 ATOM 1988 O O . ARG A 1 268 ? -7.883 3.821 63.581 1.00 29.38 ? 288 ARG A O 1 ATOM 1989 C CB . ARG A 1 268 ? -7.800 4.009 66.917 1.00 29.17 ? 288 ARG A CB 1 ATOM 1990 C CG . ARG A 1 268 ? -8.163 2.531 66.798 1.00 28.47 ? 288 ARG A CG 1 ATOM 1991 C CD . ARG A 1 268 ? -9.569 2.236 67.306 1.00 28.47 ? 288 ARG A CD 1 ATOM 1992 N NE . ARG A 1 268 ? -9.801 0.802 67.493 1.00 28.39 ? 288 ARG A NE 1 ATOM 1993 C CZ . ARG A 1 268 ? -10.928 0.265 67.960 1.00 27.84 ? 288 ARG A CZ 1 ATOM 1994 N NH1 . ARG A 1 268 ? -11.959 1.026 68.310 1.00 27.43 ? 288 ARG A NH1 1 ATOM 1995 N NH2 . ARG A 1 268 ? -11.027 -1.053 68.071 1.00 29.28 ? 288 ARG A NH2 1 ATOM 1996 N N . GLY A 1 269 ? -6.041 4.775 64.500 1.00 30.50 ? 289 GLY A N 1 ATOM 1997 C CA . GLY A 1 269 ? -5.181 4.613 63.328 1.00 30.92 ? 289 GLY A CA 1 ATOM 1998 C C . GLY A 1 269 ? -5.444 5.711 62.310 1.00 31.55 ? 289 GLY A C 1 ATOM 1999 O O . GLY A 1 269 ? -6.423 6.453 62.418 1.00 31.85 ? 289 GLY A O 1 ATOM 2000 N N . ASP A 1 270 ? -4.563 5.816 61.321 1.00 32.26 ? 290 ASP A N 1 ATOM 2001 C CA . ASP A 1 270 ? -4.697 6.797 60.250 1.00 32.99 ? 290 ASP A CA 1 ATOM 2002 C C . ASP A 1 270 ? -4.433 6.130 58.917 1.00 33.08 ? 290 ASP A C 1 ATOM 2003 O O . ASP A 1 270 ? -3.485 5.357 58.790 1.00 33.35 ? 290 ASP A O 1 ATOM 2004 C CB . ASP A 1 270 ? -3.677 7.927 60.414 1.00 33.57 ? 290 ASP A CB 1 ATOM 2005 C CG . ASP A 1 270 ? -3.766 8.606 61.759 1.00 34.56 ? 290 ASP A CG 1 ATOM 2006 O OD1 . ASP A 1 270 ? -4.689 9.425 61.958 1.00 36.47 ? 290 ASP A OD1 1 ATOM 2007 O OD2 . ASP A 1 270 ? -2.905 8.315 62.616 1.00 36.64 ? 290 ASP A OD2 1 ATOM 2008 N N . PHE A 1 271 ? -5.250 6.444 57.919 1.00 33.14 ? 291 PHE A N 1 ATOM 2009 C CA . PHE A 1 271 ? -4.971 6.015 56.554 1.00 33.12 ? 291 PHE A CA 1 ATOM 2010 C C . PHE A 1 271 ? -3.783 6.800 56.013 1.00 33.52 ? 291 PHE A C 1 ATOM 2011 O O . PHE A 1 271 ? -3.596 7.956 56.377 1.00 33.10 ? 291 PHE A O 1 ATOM 2012 C CB . PHE A 1 271 ? -6.159 6.297 55.641 1.00 33.05 ? 291 PHE A CB 1 ATOM 2013 C CG . PHE A 1 271 ? -7.386 5.484 55.939 1.00 32.01 ? 291 PHE A CG 1 ATOM 2014 C CD1 . PHE A 1 271 ? -7.308 4.116 56.159 1.00 30.91 ? 291 PHE A CD1 1 ATOM 2015 C CD2 . PHE A 1 271 ? -8.635 6.085 55.939 1.00 31.32 ? 291 PHE A CD2 1 ATOM 2016 C CE1 . PHE A 1 271 ? -8.455 3.366 56.406 1.00 30.98 ? 291 PHE A CE1 1 ATOM 2017 C CE2 . PHE A 1 271 ? -9.786 5.334 56.180 1.00 31.30 ? 291 PHE A CE2 1 ATOM 2018 C CZ . PHE A 1 271 ? -9.690 3.978 56.414 1.00 29.95 ? 291 PHE A CZ 1 ATOM 2019 N N . PRO A 1 272 ? -2.993 6.189 55.119 1.00 34.08 ? 292 PRO A N 1 ATOM 2020 C CA . PRO A 1 272 ? -1.907 6.945 54.500 1.00 34.61 ? 292 PRO A CA 1 ATOM 2021 C C . PRO A 1 272 ? -2.398 8.104 53.639 1.00 35.14 ? 292 PRO A C 1 ATOM 2022 O O . PRO A 1 272 ? -1.709 9.113 53.550 1.00 35.04 ? 292 PRO A O 1 ATOM 2023 C CB . PRO A 1 272 ? -1.166 5.902 53.651 1.00 34.64 ? 292 PRO A CB 1 ATOM 2024 C CG . PRO A 1 272 ? -2.083 4.734 53.547 1.00 34.71 ? 292 PRO A CG 1 ATOM 2025 C CD . PRO A 1 272 ? -2.964 4.766 54.751 1.00 34.29 ? 292 PRO A CD 1 ATOM 2026 N N . SER A 1 273 ? -3.574 7.964 53.023 1.00 35.83 ? 293 SER A N 1 ATOM 2027 C CA . SER A 1 273 ? -4.157 9.041 52.213 1.00 36.42 ? 293 SER A CA 1 ATOM 2028 C C . SER A 1 273 ? -5.350 9.678 52.931 1.00 36.70 ? 293 SER A C 1 ATOM 2029 O O . SER A 1 273 ? -6.467 9.178 52.804 1.00 37.34 ? 293 SER A O 1 ATOM 2030 C CB . SER A 1 273 ? -4.590 8.511 50.841 1.00 36.33 ? 293 SER A CB 1 ATOM 2031 N N . PRO A 1 274 ? -5.128 10.804 53.648 1.00 36.86 ? 294 PRO A N 1 ATOM 2032 C CA . PRO A 1 274 ? -6.167 11.408 54.505 1.00 36.85 ? 294 PRO A CA 1 ATOM 2033 C C . PRO A 1 274 ? -7.483 11.738 53.794 1.00 36.82 ? 294 PRO A C 1 ATOM 2034 O O . PRO A 1 274 ? -7.466 12.252 52.678 1.00 36.92 ? 294 PRO A O 1 ATOM 2035 C CB . PRO A 1 274 ? -5.519 12.712 55.006 1.00 36.93 ? 294 PRO A CB 1 ATOM 2036 C CG . PRO A 1 274 ? -4.071 12.624 54.657 1.00 36.87 ? 294 PRO A CG 1 ATOM 2037 C CD . PRO A 1 274 ? -3.955 11.689 53.504 1.00 36.95 ? 294 PRO A CD 1 ATOM 2038 N N . ILE A 1 275 ? -8.605 11.447 54.456 1.00 36.68 ? 295 ILE A N 1 ATOM 2039 C CA . ILE A 1 275 ? -9.945 11.787 53.968 1.00 36.51 ? 295 ILE A CA 1 ATOM 2040 C C . ILE A 1 275 ? -10.601 12.763 54.967 1.00 36.40 ? 295 ILE A C 1 ATOM 2041 O O . ILE A 1 275 ? -11.078 12.354 56.039 1.00 36.47 ? 295 ILE A O 1 ATOM 2042 C CB . ILE A 1 275 ? -10.822 10.519 53.815 1.00 36.73 ? 295 ILE A CB 1 ATOM 2043 C CG1 . ILE A 1 275 ? -10.241 9.574 52.748 1.00 37.49 ? 295 ILE A CG1 1 ATOM 2044 C CG2 . ILE A 1 275 ? -12.256 10.887 53.460 1.00 36.36 ? 295 ILE A CG2 1 ATOM 2045 C CD1 . ILE A 1 275 ? -10.959 8.229 52.664 1.00 37.62 ? 295 ILE A CD1 1 ATOM 2046 N N . HIS A 1 276 ? -10.620 14.047 54.615 1.00 35.59 ? 296 HIS A N 1 ATOM 2047 C CA . HIS A 1 276 ? -11.088 15.096 55.524 1.00 35.07 ? 296 HIS A CA 1 ATOM 2048 C C . HIS A 1 276 ? -12.523 15.560 55.269 1.00 34.38 ? 296 HIS A C 1 ATOM 2049 O O . HIS A 1 276 ? -13.072 16.324 56.067 1.00 34.71 ? 296 HIS A O 1 ATOM 2050 C CB . HIS A 1 276 ? -10.154 16.310 55.435 1.00 35.19 ? 296 HIS A CB 1 ATOM 2051 N N . VAL A 1 277 ? -13.131 15.116 54.170 1.00 33.37 ? 297 VAL A N 1 ATOM 2052 C CA . VAL A 1 277 ? -14.460 15.603 53.779 1.00 32.23 ? 297 VAL A CA 1 ATOM 2053 C C . VAL A 1 277 ? -15.477 14.479 53.697 1.00 31.48 ? 297 VAL A C 1 ATOM 2054 O O . VAL A 1 277 ? -15.115 13.306 53.637 1.00 31.18 ? 297 VAL A O 1 ATOM 2055 C CB . VAL A 1 277 ? -14.425 16.350 52.432 1.00 32.39 ? 297 VAL A CB 1 ATOM 2056 C CG1 . VAL A 1 277 ? -13.670 17.663 52.576 1.00 32.67 ? 297 VAL A CG1 1 ATOM 2057 C CG2 . VAL A 1 277 ? -13.822 15.476 51.325 1.00 31.79 ? 297 VAL A CG2 1 ATOM 2058 N N . SER A 1 278 ? -16.755 14.847 53.717 1.00 30.48 ? 298 SER A N 1 ATOM 2059 C CA . SER A 1 278 ? -17.825 13.877 53.564 1.00 29.93 ? 298 SER A CA 1 ATOM 2060 C C . SER A 1 278 ? -17.796 13.320 52.150 1.00 28.62 ? 298 SER A C 1 ATOM 2061 O O . SER A 1 278 ? -17.456 14.025 51.208 1.00 28.57 ? 298 SER A O 1 ATOM 2062 C CB . SER A 1 278 ? -19.181 14.527 53.847 1.00 30.32 ? 298 SER A CB 1 ATOM 2063 O OG . SER A 1 278 ? -19.223 15.856 53.343 1.00 32.20 ? 298 SER A OG 1 ATOM 2064 N N . GLY A 1 279 ? -18.144 12.049 52.006 1.00 27.41 ? 299 GLY A N 1 ATOM 2065 C CA . GLY A 1 279 ? -18.216 11.427 50.693 1.00 26.52 ? 299 GLY A CA 1 ATOM 2066 C C . GLY A 1 279 ? -19.432 11.903 49.924 1.00 25.54 ? 299 GLY A C 1 ATOM 2067 O O . GLY A 1 279 ? -20.246 12.664 50.441 1.00 24.80 ? 299 GLY A O 1 ATOM 2068 N N . PRO A 1 280 ? -19.574 11.445 48.679 1.00 24.95 ? 300 PRO A N 1 ATOM 2069 C CA . PRO A 1 280 ? -20.771 11.797 47.921 1.00 24.72 ? 300 PRO A CA 1 ATOM 2070 C C . PRO A 1 280 ? -22.050 11.333 48.613 1.00 24.26 ? 300 PRO A C 1 ATOM 2071 O O . PRO A 1 280 ? -22.022 10.385 49.416 1.00 24.16 ? 300 PRO A O 1 ATOM 2072 C CB . PRO A 1 280 ? -20.588 11.083 46.577 1.00 24.88 ? 300 PRO A CB 1 ATOM 2073 C CG . PRO A 1 280 ? -19.342 10.305 46.667 1.00 24.98 ? 300 PRO A CG 1 ATOM 2074 C CD . PRO A 1 280 ? -18.697 10.495 47.977 1.00 24.95 ? 300 PRO A CD 1 ATOM 2075 N N . ARG A 1 281 ? -23.154 12.000 48.291 1.00 23.49 ? 301 ARG A N 1 ATOM 2076 C CA . ARG A 1 281 ? -24.432 11.745 48.934 1.00 23.42 ? 301 ARG A CA 1 ATOM 2077 C C . ARG A 1 281 ? -25.558 11.784 47.907 1.00 23.09 ? 301 ARG A C 1 ATOM 2078 O O . ARG A 1 281 ? -25.472 12.495 46.906 1.00 22.66 ? 301 ARG A O 1 ATOM 2079 C CB . ARG A 1 281 ? -24.692 12.798 50.027 1.00 23.33 ? 301 ARG A CB 1 ATOM 2080 N N . LEU A 1 282 ? -26.609 11.014 48.167 1.00 22.81 ? 302 LEU A N 1 ATOM 2081 C CA . LEU A 1 282 ? -27.829 11.072 47.360 1.00 23.03 ? 302 LEU A CA 1 ATOM 2082 C C . LEU A 1 282 ? -28.592 12.368 47.627 1.00 22.27 ? 302 LEU A C 1 ATOM 2083 O O . LEU A 1 282 ? -28.751 12.746 48.763 1.00 22.32 ? 302 LEU A O 1 ATOM 2084 C CB . LEU A 1 282 ? -28.752 9.888 47.691 1.00 23.22 ? 302 LEU A CB 1 ATOM 2085 C CG . LEU A 1 282 ? -28.511 8.561 46.975 1.00 24.92 ? 302 LEU A CG 1 ATOM 2086 C CD1 . LEU A 1 282 ? -27.214 7.928 47.416 1.00 26.10 ? 302 LEU A CD1 1 ATOM 2087 C CD2 . LEU A 1 282 ? -29.695 7.600 47.213 1.00 24.82 ? 302 LEU A CD2 1 ATOM 2088 N N . VAL A 1 283 ? -29.047 13.048 46.579 1.00 22.27 ? 303 VAL A N 1 ATOM 2089 C CA . VAL A 1 283 ? -30.047 14.107 46.715 1.00 22.02 ? 303 VAL A CA 1 ATOM 2090 C C . VAL A 1 283 ? -31.306 13.697 45.969 1.00 21.74 ? 303 VAL A C 1 ATOM 2091 O O . VAL A 1 283 ? -31.240 12.960 44.998 1.00 21.67 ? 303 VAL A O 1 ATOM 2092 C CB . VAL A 1 283 ? -29.552 15.471 46.173 1.00 22.46 ? 303 VAL A CB 1 ATOM 2093 C CG1 . VAL A 1 283 ? -28.327 15.956 46.960 1.00 22.31 ? 303 VAL A CG1 1 ATOM 2094 C CG2 . VAL A 1 283 ? -29.263 15.391 44.673 1.00 22.88 ? 303 VAL A CG2 1 ATOM 2095 N N . GLN A 1 284 ? -32.455 14.173 46.432 1.00 22.01 ? 304 GLN A N 1 ATOM 2096 C CA . GLN A 1 284 ? -33.741 13.818 45.834 1.00 21.77 ? 304 GLN A CA 1 ATOM 2097 C C . GLN A 1 284 ? -34.640 15.073 45.726 1.00 22.15 ? 304 GLN A C 1 ATOM 2098 O O . GLN A 1 284 ? -35.691 15.145 46.334 1.00 21.44 ? 304 GLN A O 1 ATOM 2099 C CB . GLN A 1 284 ? -34.413 12.695 46.646 1.00 21.63 ? 304 GLN A CB 1 ATOM 2100 C CG . GLN A 1 284 ? -35.533 11.967 45.897 1.00 21.04 ? 304 GLN A CG 1 ATOM 2101 C CD . GLN A 1 284 ? -36.161 10.844 46.698 1.00 20.40 ? 304 GLN A CD 1 ATOM 2102 O OE1 . GLN A 1 284 ? -36.208 9.699 46.241 1.00 19.44 ? 304 GLN A OE1 1 ATOM 2103 N NE2 . GLN A 1 284 ? -36.648 11.162 47.903 1.00 20.19 ? 304 GLN A NE2 1 ATOM 2104 N N . PRO A 1 285 ? -34.218 16.060 44.919 1.00 22.89 ? 305 PRO A N 1 ATOM 2105 C CA . PRO A 1 285 ? -34.940 17.327 44.751 1.00 23.34 ? 305 PRO A CA 1 ATOM 2106 C C . PRO A 1 285 ? -36.393 17.182 44.295 1.00 23.74 ? 305 PRO A C 1 ATOM 2107 O O . PRO A 1 285 ? -37.241 18.009 44.652 1.00 23.67 ? 305 PRO A O 1 ATOM 2108 C CB . PRO A 1 285 ? -34.139 18.026 43.646 1.00 23.68 ? 305 PRO A CB 1 ATOM 2109 C CG . PRO A 1 285 ? -33.450 16.894 42.913 1.00 23.19 ? 305 PRO A CG 1 ATOM 2110 C CD . PRO A 1 285 ? -33.047 16.002 44.029 1.00 22.80 ? 305 PRO A CD 1 ATOM 2111 N N . HIS A 1 286 ? -36.669 16.144 43.511 1.00 23.85 ? 306 HIS A N 1 ATOM 2112 C CA . HIS A 1 286 ? -38.010 15.906 43.002 1.00 24.29 ? 306 HIS A CA 1 ATOM 2113 C C . HIS A 1 286 ? -38.865 15.066 43.939 1.00 23.63 ? 306 HIS A C 1 ATOM 2114 O O . HIS A 1 286 ? -40.031 14.842 43.660 1.00 24.16 ? 306 HIS A O 1 ATOM 2115 C CB . HIS A 1 286 ? -37.917 15.253 41.636 1.00 24.99 ? 306 HIS A CB 1 ATOM 2116 C CG . HIS A 1 286 ? -37.072 16.029 40.679 1.00 27.43 ? 306 HIS A CG 1 ATOM 2117 N ND1 . HIS A 1 286 ? -37.427 17.280 40.222 1.00 30.72 ? 306 HIS A ND1 1 ATOM 2118 C CD2 . HIS A 1 286 ? -35.862 15.759 40.139 1.00 30.55 ? 306 HIS A CD2 1 ATOM 2119 C CE1 . HIS A 1 286 ? -36.482 17.737 39.420 1.00 31.78 ? 306 HIS A CE1 1 ATOM 2120 N NE2 . HIS A 1 286 ? -35.522 16.831 39.349 1.00 31.87 ? 306 HIS A NE2 1 ATOM 2121 N N . GLY A 1 287 ? -38.292 14.618 45.056 1.00 22.92 ? 307 GLY A N 1 ATOM 2122 C CA . GLY A 1 287 ? -39.019 13.803 46.018 1.00 22.24 ? 307 GLY A CA 1 ATOM 2123 C C . GLY A 1 287 ? -39.085 12.354 45.586 1.00 21.51 ? 307 GLY A C 1 ATOM 2124 O O . GLY A 1 287 ? -38.523 11.989 44.556 1.00 21.04 ? 307 GLY A O 1 ATOM 2125 N N . PRO A 1 288 ? -39.773 11.509 46.373 1.00 21.07 ? 308 PRO A N 1 ATOM 2126 C CA . PRO A 1 288 ? -39.851 10.085 46.029 1.00 20.84 ? 308 PRO A CA 1 ATOM 2127 C C . PRO A 1 288 ? -40.556 9.837 44.712 1.00 20.84 ? 308 PRO A C 1 ATOM 2128 O O . PRO A 1 288 ? -41.505 10.546 44.372 1.00 20.72 ? 308 PRO A O 1 ATOM 2129 C CB . PRO A 1 288 ? -40.660 9.482 47.185 1.00 20.86 ? 308 PRO A CB 1 ATOM 2130 C CG . PRO A 1 288 ? -40.532 10.481 48.310 1.00 20.84 ? 308 PRO A CG 1 ATOM 2131 C CD . PRO A 1 288 ? -40.453 11.809 47.646 1.00 20.92 ? 308 PRO A CD 1 ATOM 2132 N N . ARG A 1 289 ? -40.076 8.851 43.964 1.00 21.21 ? 309 ARG A N 1 ATOM 2133 C CA . ARG A 1 289 ? -40.719 8.445 42.712 1.00 21.24 ? 309 ARG A CA 1 ATOM 2134 C C . ARG A 1 289 ? -41.637 7.241 42.904 1.00 21.07 ? 309 ARG A C 1 ATOM 2135 O O . ARG A 1 289 ? -42.415 6.890 42.002 1.00 21.37 ? 309 ARG A O 1 ATOM 2136 C CB . ARG A 1 289 ? -39.668 8.144 41.663 1.00 21.13 ? 309 ARG A CB 1 ATOM 2137 C CG . ARG A 1 289 ? -38.794 9.337 41.373 1.00 21.26 ? 309 ARG A CG 1 ATOM 2138 C CD . ARG A 1 289 ? -38.171 9.250 39.991 1.00 21.82 ? 309 ARG A CD 1 ATOM 2139 N NE . ARG A 1 289 ? -37.357 8.048 39.802 1.00 20.09 ? 309 ARG A NE 1 ATOM 2140 C CZ . ARG A 1 289 ? -36.823 7.675 38.633 1.00 20.74 ? 309 ARG A CZ 1 ATOM 2141 N NH1 . ARG A 1 289 ? -37.005 8.401 37.536 1.00 20.29 ? 309 ARG A NH1 1 ATOM 2142 N NH2 . ARG A 1 289 ? -36.107 6.555 38.552 1.00 20.38 ? 309 ARG A NH2 1 ATOM 2143 N N . PHE A 1 290 ? -41.549 6.619 44.078 1.00 20.31 ? 310 PHE A N 1 ATOM 2144 C CA . PHE A 1 290 ? -42.523 5.603 44.489 1.00 19.68 ? 310 PHE A CA 1 ATOM 2145 C C . PHE A 1 290 ? -43.655 6.271 45.270 1.00 19.58 ? 310 PHE A C 1 ATOM 2146 O O . PHE A 1 290 ? -43.479 7.363 45.825 1.00 18.72 ? 310 PHE A O 1 ATOM 2147 C CB . PHE A 1 290 ? -41.854 4.522 45.348 1.00 19.43 ? 310 PHE A CB 1 ATOM 2148 C CG . PHE A 1 290 ? -41.115 5.065 46.547 1.00 18.88 ? 310 PHE A CG 1 ATOM 2149 C CD1 . PHE A 1 290 ? -41.771 5.269 47.750 1.00 17.14 ? 310 PHE A CD1 1 ATOM 2150 C CD2 . PHE A 1 290 ? -39.765 5.387 46.461 1.00 17.91 ? 310 PHE A CD2 1 ATOM 2151 C CE1 . PHE A 1 290 ? -41.103 5.772 48.846 1.00 16.71 ? 310 PHE A CE1 1 ATOM 2152 C CE2 . PHE A 1 290 ? -39.083 5.900 47.556 1.00 17.47 ? 310 PHE A CE2 1 ATOM 2153 C CZ . PHE A 1 290 ? -39.747 6.090 48.751 1.00 17.19 ? 310 PHE A CZ 1 ATOM 2154 N N . ARG A 1 291 ? -44.807 5.602 45.321 1.00 19.35 ? 311 ARG A N 1 ATOM 2155 C CA . ARG A 1 291 ? -45.950 6.081 46.079 1.00 19.45 ? 311 ARG A CA 1 ATOM 2156 C C . ARG A 1 291 ? -46.168 5.158 47.271 1.00 19.53 ? 311 ARG A C 1 ATOM 2157 O O . ARG A 1 291 ? -46.635 4.031 47.115 1.00 19.89 ? 311 ARG A O 1 ATOM 2158 C CB . ARG A 1 291 ? -47.202 6.099 45.212 1.00 19.47 ? 311 ARG A CB 1 ATOM 2159 C CG . ARG A 1 291 ? -46.993 6.702 43.851 1.00 20.55 ? 311 ARG A CG 1 ATOM 2160 C CD . ARG A 1 291 ? -48.304 6.857 43.124 1.00 21.32 ? 311 ARG A CD 1 ATOM 2161 N NE . ARG A 1 291 ? -48.087 7.020 41.695 1.00 23.24 ? 311 ARG A NE 1 ATOM 2162 C CZ . ARG A 1 291 ? -49.054 7.011 40.779 1.00 24.76 ? 311 ARG A CZ 1 ATOM 2163 N NH1 . ARG A 1 291 ? -50.320 6.839 41.133 1.00 24.51 ? 311 ARG A NH1 1 ATOM 2164 N NH2 . ARG A 1 291 ? -48.746 7.170 39.501 1.00 25.56 ? 311 ARG A NH2 1 ATOM 2165 N N . LEU A 1 292 ? -45.812 5.638 48.452 1.00 18.98 ? 312 LEU A N 1 ATOM 2166 C CA . LEU A 1 292 ? -46.006 4.902 49.687 1.00 18.89 ? 312 LEU A CA 1 ATOM 2167 C C . LEU A 1 292 ? -47.195 5.540 50.394 1.00 19.03 ? 312 LEU A C 1 ATOM 2168 O O . LEU A 1 292 ? -47.171 6.730 50.723 1.00 18.65 ? 312 LEU A O 1 ATOM 2169 C CB . LEU A 1 292 ? -44.761 4.988 50.567 1.00 18.60 ? 312 LEU A CB 1 ATOM 2170 C CG . LEU A 1 292 ? -44.850 4.539 52.039 1.00 19.51 ? 312 LEU A CG 1 ATOM 2171 C CD1 . LEU A 1 292 ? -45.158 3.054 52.151 1.00 20.16 ? 312 LEU A CD1 1 ATOM 2172 C CD2 . LEU A 1 292 ? -43.546 4.879 52.783 1.00 17.91 ? 312 LEU A CD2 1 ATOM 2173 N N . GLU A 1 293 ? -48.236 4.752 50.592 1.00 18.94 ? 313 GLU A N 1 ATOM 2174 C CA . GLU A 1 293 ? -49.386 5.182 51.346 1.00 19.62 ? 313 GLU A CA 1 ATOM 2175 C C . GLU A 1 293 ? -49.825 4.022 52.251 1.00 19.67 ? 313 GLU A C 1 ATOM 2176 O O . GLU A 1 293 ? -50.203 2.957 51.773 1.00 19.48 ? 313 GLU A O 1 ATOM 2177 C CB . GLU A 1 293 ? -50.504 5.626 50.403 1.00 19.61 ? 313 GLU A CB 1 ATOM 2178 C CG . GLU A 1 293 ? -51.651 6.273 51.133 1.00 21.43 ? 313 GLU A CG 1 ATOM 2179 C CD . GLU A 1 293 ? -52.746 6.760 50.207 1.00 23.29 ? 313 GLU A CD 1 ATOM 2180 O OE1 . GLU A 1 293 ? -52.628 6.616 48.977 1.00 25.24 ? 313 GLU A OE1 1 ATOM 2181 O OE2 . GLU A 1 293 ? -53.735 7.292 50.725 1.00 26.74 ? 313 GLU A OE2 1 ATOM 2182 N N . GLY A 1 294 ? -49.749 4.243 53.559 1.00 20.08 ? 314 GLY A N 1 ATOM 2183 C CA . GLY A 1 294 ? -49.937 3.187 54.539 1.00 20.52 ? 314 GLY A CA 1 ATOM 2184 C C . GLY A 1 294 ? -48.885 2.110 54.353 1.00 20.72 ? 314 GLY A C 1 ATOM 2185 O O . GLY A 1 294 ? -47.671 2.378 54.364 1.00 21.31 ? 314 GLY A O 1 ATOM 2186 N N . ASN A 1 295 ? -49.344 0.887 54.166 1.00 20.58 ? 315 ASN A N 1 ATOM 2187 C CA . ASN A 1 295 ? -48.438 -0.213 53.869 1.00 20.53 ? 315 ASN A CA 1 ATOM 2188 C C . ASN A 1 295 ? -48.538 -0.637 52.396 1.00 20.10 ? 315 ASN A C 1 ATOM 2189 O O . ASN A 1 295 ? -48.221 -1.775 52.061 1.00 20.30 ? 315 ASN A O 1 ATOM 2190 C CB . ASN A 1 295 ? -48.712 -1.376 54.826 1.00 20.75 ? 315 ASN A CB 1 ATOM 2191 C CG . ASN A 1 295 ? -50.020 -2.099 54.523 1.00 21.87 ? 315 ASN A CG 1 ATOM 2192 O OD1 . ASN A 1 295 ? -51.028 -1.475 54.171 1.00 23.48 ? 315 ASN A OD1 1 ATOM 2193 N ND2 . ASN A 1 295 ? -49.996 -3.425 54.622 1.00 21.91 ? 315 ASN A ND2 1 ATOM 2194 N N . ALA A 1 296 ? -48.967 0.287 51.526 1.00 19.65 ? 316 ALA A N 1 ATOM 2195 C CA . ALA A 1 296 ? -49.078 0.036 50.082 1.00 19.29 ? 316 ALA A CA 1 ATOM 2196 C C . ALA A 1 296 ? -47.998 0.811 49.344 1.00 19.08 ? 316 ALA A C 1 ATOM 2197 O O . ALA A 1 296 ? -47.790 1.993 49.609 1.00 19.06 ? 316 ALA A O 1 ATOM 2198 C CB . ALA A 1 296 ? -50.452 0.451 49.554 1.00 18.69 ? 316 ALA A CB 1 ATOM 2199 N N . VAL A 1 297 ? -47.345 0.151 48.394 1.00 18.68 ? 317 VAL A N 1 ATOM 2200 C CA . VAL A 1 297 ? -46.298 0.772 47.599 1.00 18.44 ? 317 VAL A CA 1 ATOM 2201 C C . VAL A 1 297 ? -46.574 0.589 46.111 1.00 18.34 ? 317 VAL A C 1 ATOM 2202 O O . VAL A 1 297 ? -46.932 -0.506 45.650 1.00 18.13 ? 317 VAL A O 1 ATOM 2203 C CB . VAL A 1 297 ? -44.900 0.192 47.966 1.00 18.67 ? 317 VAL A CB 1 ATOM 2204 C CG1 . VAL A 1 297 ? -43.796 0.818 47.104 1.00 17.66 ? 317 VAL A CG1 1 ATOM 2205 C CG2 . VAL A 1 297 ? -44.614 0.419 49.445 1.00 17.85 ? 317 VAL A CG2 1 ATOM 2206 N N . LEU A 1 298 ? -46.436 1.688 45.376 1.00 18.53 ? 318 LEU A N 1 ATOM 2207 C CA . LEU A 1 298 ? -46.404 1.681 43.912 1.00 18.46 ? 318 LEU A CA 1 ATOM 2208 C C . LEU A 1 298 ? -45.052 2.244 43.479 1.00 18.38 ? 318 LEU A C 1 ATOM 2209 O O . LEU A 1 298 ? -44.599 3.225 44.027 1.00 18.36 ? 318 LEU A O 1 ATOM 2210 C CB . LEU A 1 298 ? -47.546 2.528 43.352 1.00 18.35 ? 318 LEU A CB 1 ATOM 2211 C CG . LEU A 1 298 ? -48.953 2.077 43.797 1.00 19.27 ? 318 LEU A CG 1 ATOM 2212 C CD1 . LEU A 1 298 ? -50.027 3.144 43.536 1.00 18.54 ? 318 LEU A CD1 1 ATOM 2213 C CD2 . LEU A 1 298 ? -49.320 0.761 43.100 1.00 19.81 ? 318 LEU A CD2 1 ATOM 2214 N N . TYR A 1 299 ? -44.406 1.597 42.514 1.00 18.76 ? 319 TYR A N 1 ATOM 2215 C CA . TYR A 1 299 ? -43.105 2.018 42.005 1.00 18.80 ? 319 TYR A CA 1 ATOM 2216 C C . TYR A 1 299 ? -42.961 1.513 40.571 1.00 19.31 ? 319 TYR A C 1 ATOM 2217 O O . TYR A 1 299 ? -42.660 0.336 40.347 1.00 18.38 ? 319 TYR A O 1 ATOM 2218 C CB . TYR A 1 299 ? -41.978 1.453 42.870 1.00 19.15 ? 319 TYR A CB 1 ATOM 2219 C CG . TYR A 1 299 ? -40.577 1.700 42.336 1.00 19.43 ? 319 TYR A CG 1 ATOM 2220 C CD1 . TYR A 1 299 ? -40.103 2.989 42.139 1.00 19.63 ? 319 TYR A CD1 1 ATOM 2221 C CD2 . TYR A 1 299 ? -39.724 0.639 42.044 1.00 20.99 ? 319 TYR A CD2 1 ATOM 2222 C CE1 . TYR A 1 299 ? -38.818 3.218 41.659 1.00 20.77 ? 319 TYR A CE1 1 ATOM 2223 C CE2 . TYR A 1 299 ? -38.435 0.859 41.564 1.00 20.51 ? 319 TYR A CE2 1 ATOM 2224 C CZ . TYR A 1 299 ? -37.992 2.147 41.377 1.00 20.46 ? 319 TYR A CZ 1 ATOM 2225 O OH . TYR A 1 299 ? -36.725 2.371 40.905 1.00 20.25 ? 319 TYR A OH 1 ATOM 2226 N N . GLY A 1 300 ? -43.197 2.410 39.615 1.00 19.43 ? 320 GLY A N 1 ATOM 2227 C CA . GLY A 1 300 ? -43.236 2.064 38.194 1.00 19.81 ? 320 GLY A CA 1 ATOM 2228 C C . GLY A 1 300 ? -44.172 0.909 37.902 1.00 19.72 ? 320 GLY A C 1 ATOM 2229 O O . GLY A 1 300 ? -45.415 1.027 38.031 1.00 20.00 ? 320 GLY A O 1 ATOM 2230 N N . GLY A 1 301 ? -43.580 -0.216 37.509 1.00 19.28 ? 321 GLY A N 1 ATOM 2231 C CA . GLY A 1 301 ? -44.342 -1.418 37.215 1.00 18.94 ? 321 GLY A CA 1 ATOM 2232 C C . GLY A 1 301 ? -44.864 -2.105 38.462 1.00 19.00 ? 321 GLY A C 1 ATOM 2233 O O . GLY A 1 301 ? -45.816 -2.888 38.385 1.00 18.57 ? 321 GLY A O 1 ATOM 2234 N N . TRP A 1 302 ? -44.252 -1.813 39.612 1.00 19.03 ? 322 TRP A N 1 ATOM 2235 C CA . TRP A 1 302 ? -44.517 -2.568 40.837 1.00 19.02 ? 322 TRP A CA 1 ATOM 2236 C C . TRP A 1 302 ? -45.733 -2.115 41.633 1.00 19.29 ? 322 TRP A C 1 ATOM 2237 O O . TRP A 1 302 ? -46.065 -0.929 41.687 1.00 19.26 ? 322 TRP A O 1 ATOM 2238 C CB . TRP A 1 302 ? -43.321 -2.496 41.772 1.00 18.84 ? 322 TRP A CB 1 ATOM 2239 C CG . TRP A 1 302 ? -42.075 -3.137 41.250 1.00 18.55 ? 322 TRP A CG 1 ATOM 2240 C CD1 . TRP A 1 302 ? -41.019 -2.515 40.656 1.00 17.60 ? 322 TRP A CD1 1 ATOM 2241 C CD2 . TRP A 1 302 ? -41.747 -4.531 41.300 1.00 18.10 ? 322 TRP A CD2 1 ATOM 2242 N NE1 . TRP A 1 302 ? -40.048 -3.437 40.330 1.00 19.06 ? 322 TRP A NE1 1 ATOM 2243 C CE2 . TRP A 1 302 ? -40.474 -4.682 40.709 1.00 18.40 ? 322 TRP A CE2 1 ATOM 2244 C CE3 . TRP A 1 302 ? -42.418 -5.669 41.757 1.00 17.72 ? 322 TRP A CE3 1 ATOM 2245 C CZ2 . TRP A 1 302 ? -39.851 -5.922 40.594 1.00 19.23 ? 322 TRP A CZ2 1 ATOM 2246 C CZ3 . TRP A 1 302 ? -41.796 -6.906 41.636 1.00 17.62 ? 322 TRP A CZ3 1 ATOM 2247 C CH2 . TRP A 1 302 ? -40.530 -7.022 41.058 1.00 18.46 ? 322 TRP A CH2 1 ATOM 2248 N N . SER A 1 303 ? -46.356 -3.084 42.289 1.00 19.46 ? 323 SER A N 1 ATOM 2249 C CA . SER A 1 303 ? -47.361 -2.837 43.308 1.00 19.87 ? 323 SER A CA 1 ATOM 2250 C C . SER A 1 303 ? -47.225 -3.911 44.374 1.00 19.73 ? 323 SER A C 1 ATOM 2251 O O . SER A 1 303 ? -47.256 -5.081 44.057 1.00 19.78 ? 323 SER A O 1 ATOM 2252 C CB . SER A 1 303 ? -48.761 -2.899 42.704 1.00 19.98 ? 323 SER A CB 1 ATOM 2253 O OG . SER A 1 303 ? -49.734 -2.809 43.719 1.00 21.84 ? 323 SER A OG 1 ATOM 2254 N N . PHE A 1 304 ? -47.066 -3.514 45.631 1.00 19.77 ? 324 PHE A N 1 ATOM 2255 C CA . PHE A 1 304 ? -47.002 -4.475 46.720 1.00 19.78 ? 324 PHE A CA 1 ATOM 2256 C C . PHE A 1 304 ? -47.407 -3.859 48.055 1.00 19.48 ? 324 PHE A C 1 ATOM 2257 O O . PHE A 1 304 ? -47.476 -2.644 48.197 1.00 19.31 ? 324 PHE A O 1 ATOM 2258 C CB . PHE A 1 304 ? -45.599 -5.099 46.816 1.00 20.08 ? 324 PHE A CB 1 ATOM 2259 C CG . PHE A 1 304 ? -44.500 -4.120 47.180 1.00 19.57 ? 324 PHE A CG 1 ATOM 2260 C CD1 . PHE A 1 304 ? -44.168 -3.893 48.512 1.00 18.85 ? 324 PHE A CD1 1 ATOM 2261 C CD2 . PHE A 1 304 ? -43.755 -3.486 46.185 1.00 19.38 ? 324 PHE A CD2 1 ATOM 2262 C CE1 . PHE A 1 304 ? -43.131 -3.015 48.857 1.00 19.03 ? 324 PHE A CE1 1 ATOM 2263 C CE2 . PHE A 1 304 ? -42.714 -2.600 46.513 1.00 18.84 ? 324 PHE A CE2 1 ATOM 2264 C CZ . PHE A 1 304 ? -42.406 -2.358 47.850 1.00 19.31 ? 324 PHE A CZ 1 ATOM 2265 N N . ALA A 1 305 ? -47.706 -4.718 49.015 1.00 19.27 ? 325 ALA A N 1 ATOM 2266 C CA . ALA A 1 305 ? -47.964 -4.300 50.390 1.00 19.27 ? 325 ALA A CA 1 ATOM 2267 C C . ALA A 1 305 ? -46.869 -4.901 51.247 1.00 19.32 ? 325 ALA A C 1 ATOM 2268 O O . ALA A 1 305 ? -46.183 -5.827 50.825 1.00 18.79 ? 325 ALA A O 1 ATOM 2269 C CB . ALA A 1 305 ? -49.341 -4.780 50.860 1.00 18.96 ? 325 ALA A CB 1 ATOM 2270 N N . PHE A 1 306 ? -46.681 -4.372 52.444 1.00 19.96 ? 326 PHE A N 1 ATOM 2271 C CA . PHE A 1 306 ? -45.703 -4.953 53.352 1.00 21.12 ? 326 PHE A CA 1 ATOM 2272 C C . PHE A 1 306 ? -46.235 -4.976 54.758 1.00 21.48 ? 326 PHE A C 1 ATOM 2273 O O . PHE A 1 306 ? -47.231 -4.336 55.077 1.00 22.04 ? 326 PHE A O 1 ATOM 2274 C CB . PHE A 1 306 ? -44.367 -4.199 53.310 1.00 20.99 ? 326 PHE A CB 1 ATOM 2275 C CG . PHE A 1 306 ? -44.481 -2.755 53.690 1.00 23.00 ? 326 PHE A CG 1 ATOM 2276 C CD1 . PHE A 1 306 ? -44.353 -2.359 55.012 1.00 23.52 ? 326 PHE A CD1 1 ATOM 2277 C CD2 . PHE A 1 306 ? -44.737 -1.790 52.721 1.00 23.26 ? 326 PHE A CD2 1 ATOM 2278 C CE1 . PHE A 1 306 ? -44.483 -1.027 55.358 1.00 24.51 ? 326 PHE A CE1 1 ATOM 2279 C CE2 . PHE A 1 306 ? -44.855 -0.468 53.063 1.00 23.65 ? 326 PHE A CE2 1 ATOM 2280 C CZ . PHE A 1 306 ? -44.730 -0.084 54.383 1.00 23.81 ? 326 PHE A CZ 1 ATOM 2281 N N . ARG A 1 307 ? -45.570 -5.751 55.591 1.00 21.87 ? 327 ARG A N 1 ATOM 2282 C CA . ARG A 1 307 ? -45.821 -5.713 57.016 1.00 22.42 ? 327 ARG A CA 1 ATOM 2283 C C . ARG A 1 307 ? -44.566 -6.172 57.721 1.00 22.12 ? 327 ARG A C 1 ATOM 2284 O O . ARG A 1 307 ? -43.669 -6.759 57.108 1.00 21.79 ? 327 ARG A O 1 ATOM 2285 C CB . ARG A 1 307 ? -46.982 -6.611 57.399 1.00 22.57 ? 327 ARG A CB 1 ATOM 2286 C CG . ARG A 1 307 ? -46.636 -8.079 57.363 1.00 24.58 ? 327 ARG A CG 1 ATOM 2287 C CD . ARG A 1 307 ? -47.705 -8.921 58.017 1.00 25.95 ? 327 ARG A CD 1 ATOM 2288 N NE . ARG A 1 307 ? -47.777 -8.717 59.460 1.00 26.97 ? 327 ARG A NE 1 ATOM 2289 C CZ . ARG A 1 307 ? -48.355 -9.567 60.308 1.00 26.13 ? 327 ARG A CZ 1 ATOM 2290 N NH1 . ARG A 1 307 ? -48.371 -9.293 61.609 1.00 26.39 ? 327 ARG A NH1 1 ATOM 2291 N NH2 . ARG A 1 307 ? -48.891 -10.704 59.866 1.00 26.29 ? 327 ARG A NH2 1 ATOM 2292 N N . LEU A 1 308 ? -44.519 -5.890 59.011 1.00 22.09 ? 328 LEU A N 1 ATOM 2293 C CA . LEU A 1 308 ? -43.413 -6.279 59.842 1.00 22.50 ? 328 LEU A CA 1 ATOM 2294 C C . LEU A 1 308 ? -43.990 -7.098 60.998 1.00 22.65 ? 328 LEU A C 1 ATOM 2295 O O . LEU A 1 308 ? -44.472 -6.556 61.989 1.00 22.79 ? 328 LEU A O 1 ATOM 2296 C CB . LEU A 1 308 ? -42.679 -5.031 60.315 1.00 22.41 ? 328 LEU A CB 1 ATOM 2297 C CG . LEU A 1 308 ? -41.505 -5.235 61.268 1.00 23.14 ? 328 LEU A CG 1 ATOM 2298 C CD1 . LEU A 1 308 ? -40.376 -5.996 60.594 1.00 22.97 ? 328 LEU A CD1 1 ATOM 2299 C CD2 . LEU A 1 308 ? -41.030 -3.880 61.772 1.00 24.60 ? 328 LEU A CD2 1 ATOM 2300 N N . ARG A 1 309 ? -43.978 -8.410 60.834 1.00 23.28 ? 329 ARG A N 1 ATOM 2301 C CA . ARG A 1 309 ? -44.505 -9.318 61.849 1.00 23.83 ? 329 ARG A CA 1 ATOM 2302 C C . ARG A 1 309 ? -43.560 -9.291 63.045 1.00 23.27 ? 329 ARG A C 1 ATOM 2303 O O . ARG A 1 309 ? -42.370 -9.580 62.907 1.00 23.01 ? 329 ARG A O 1 ATOM 2304 C CB . ARG A 1 309 ? -44.641 -10.718 61.256 1.00 24.42 ? 329 ARG A CB 1 ATOM 2305 C CG . ARG A 1 309 ? -45.374 -11.755 62.105 1.00 27.51 ? 329 ARG A CG 1 ATOM 2306 C CD . ARG A 1 309 ? -45.865 -12.896 61.206 1.00 31.21 ? 329 ARG A CD 1 ATOM 2307 N NE . ARG A 1 309 ? -46.360 -14.070 61.938 1.00 35.96 ? 329 ARG A NE 1 ATOM 2308 C CZ . ARG A 1 309 ? -45.659 -15.187 62.189 1.00 38.61 ? 329 ARG A CZ 1 ATOM 2309 N NH1 . ARG A 1 309 ? -44.393 -15.318 61.800 1.00 38.87 ? 329 ARG A NH1 1 ATOM 2310 N NH2 . ARG A 1 309 ? -46.230 -16.192 62.847 1.00 39.25 ? 329 ARG A NH2 1 ATOM 2311 N N . SER A 1 310 ? -44.079 -8.891 64.204 1.00 23.17 ? 330 SER A N 1 ATOM 2312 C CA . SER A 1 310 ? -43.278 -8.813 65.431 1.00 23.32 ? 330 SER A CA 1 ATOM 2313 C C . SER A 1 310 ? -42.513 -10.102 65.745 1.00 23.47 ? 330 SER A C 1 ATOM 2314 O O . SER A 1 310 ? -41.376 -10.056 66.231 1.00 23.49 ? 330 SER A O 1 ATOM 2315 C CB . SER A 1 310 ? -44.167 -8.442 66.633 1.00 23.58 ? 330 SER A CB 1 ATOM 2316 O OG . SER A 1 310 ? -44.534 -7.076 66.601 1.00 22.98 ? 330 SER A OG 1 ATOM 2317 N N . SER A 1 311 ? -43.129 -11.250 65.480 1.00 23.59 ? 331 SER A N 1 ATOM 2318 C CA . SER A 1 311 ? -42.485 -12.525 65.791 1.00 24.32 ? 331 SER A CA 1 ATOM 2319 C C . SER A 1 311 ? -41.318 -12.835 64.829 1.00 25.07 ? 331 SER A C 1 ATOM 2320 O O . SER A 1 311 ? -40.167 -13.013 65.276 1.00 26.11 ? 331 SER A O 1 ATOM 2321 C CB . SER A 1 311 ? -43.501 -13.675 65.817 1.00 23.71 ? 331 SER A CB 1 ATOM 2322 O OG . SER A 1 311 ? -44.286 -13.715 64.638 1.00 23.16 ? 331 SER A OG 1 ATOM 2323 N N . SER A 1 312 ? -41.610 -12.854 63.530 1.00 25.29 ? 332 SER A N 1 ATOM 2324 C CA . SER A 1 312 ? -40.678 -13.351 62.503 1.00 25.28 ? 332 SER A CA 1 ATOM 2325 C C . SER A 1 312 ? -40.003 -12.293 61.622 1.00 25.46 ? 332 SER A C 1 ATOM 2326 O O . SER A 1 312 ? -38.943 -12.564 61.060 1.00 25.99 ? 332 SER A O 1 ATOM 2327 C CB . SER A 1 312 ? -41.407 -14.343 61.603 1.00 25.12 ? 332 SER A CB 1 ATOM 2328 O OG . SER A 1 312 ? -42.531 -13.739 61.008 1.00 24.78 ? 332 SER A OG 1 ATOM 2329 N N . GLY A 1 313 ? -40.613 -11.117 61.476 1.00 25.41 ? 333 GLY A N 1 ATOM 2330 C CA . GLY A 1 313 ? -40.006 -10.014 60.721 1.00 25.14 ? 333 GLY A CA 1 ATOM 2331 C C . GLY A 1 313 ? -40.719 -9.613 59.432 1.00 25.14 ? 333 GLY A C 1 ATOM 2332 O O . GLY A 1 313 ? -41.938 -9.791 59.289 1.00 24.90 ? 333 GLY A O 1 ATOM 2333 N N . LEU A 1 314 ? -39.927 -9.095 58.494 1.00 24.75 ? 334 LEU A N 1 ATOM 2334 C CA . LEU A 1 314 ? -40.408 -8.390 57.298 1.00 24.63 ? 334 LEU A CA 1 ATOM 2335 C C . LEU A 1 314 ? -41.081 -9.307 56.287 1.00 25.09 ? 334 LEU A C 1 ATOM 2336 O O . LEU A 1 314 ? -40.599 -10.411 56.010 1.00 24.96 ? 334 LEU A O 1 ATOM 2337 C CB . LEU A 1 314 ? -39.225 -7.683 56.621 1.00 24.46 ? 334 LEU A CB 1 ATOM 2338 C CG . LEU A 1 314 ? -39.477 -6.474 55.716 1.00 24.18 ? 334 LEU A CG 1 ATOM 2339 C CD1 . LEU A 1 314 ? -40.089 -5.345 56.494 1.00 21.92 ? 334 LEU A CD1 1 ATOM 2340 C CD2 . LEU A 1 314 ? -38.167 -6.006 55.099 1.00 23.20 ? 334 LEU A CD2 1 ATOM 2341 N N . GLN A 1 315 ? -42.202 -8.844 55.733 1.00 25.61 ? 335 GLN A N 1 ATOM 2342 C CA . GLN A 1 315 ? -42.877 -9.538 54.633 1.00 25.54 ? 335 GLN A CA 1 ATOM 2343 C C . GLN A 1 315 ? -43.311 -8.563 53.569 1.00 25.03 ? 335 GLN A C 1 ATOM 2344 O O . GLN A 1 315 ? -43.748 -7.456 53.894 1.00 25.89 ? 335 GLN A O 1 ATOM 2345 C CB . GLN A 1 315 ? -44.124 -10.233 55.134 1.00 25.98 ? 335 GLN A CB 1 ATOM 2346 C CG . GLN A 1 315 ? -43.946 -10.990 56.414 1.00 27.16 ? 335 GLN A CG 1 ATOM 2347 C CD . GLN A 1 315 ? -45.093 -11.919 56.664 1.00 29.15 ? 335 GLN A CD 1 ATOM 2348 O OE1 . GLN A 1 315 ? -46.148 -11.805 56.040 1.00 30.64 ? 335 GLN A OE1 1 ATOM 2349 N NE2 . GLN A 1 315 ? -44.899 -12.853 57.574 1.00 31.42 ? 335 GLN A NE2 1 ATOM 2350 N N . VAL A 1 316 ? -43.199 -8.960 52.305 1.00 24.11 ? 336 VAL A N 1 ATOM 2351 C CA . VAL A 1 316 ? -43.862 -8.234 51.228 1.00 23.49 ? 336 VAL A CA 1 ATOM 2352 C C . VAL A 1 316 ? -44.961 -9.130 50.682 1.00 22.64 ? 336 VAL A C 1 ATOM 2353 O O . VAL A 1 316 ? -44.761 -10.330 50.467 1.00 21.90 ? 336 VAL A O 1 ATOM 2354 C CB . VAL A 1 316 ? -42.904 -7.742 50.112 1.00 23.38 ? 336 VAL A CB 1 ATOM 2355 C CG1 . VAL A 1 316 ? -41.885 -6.769 50.687 1.00 24.56 ? 336 VAL A CG1 1 ATOM 2356 C CG2 . VAL A 1 316 ? -42.210 -8.895 49.422 1.00 24.75 ? 336 VAL A CG2 1 ATOM 2357 N N . LEU A 1 317 ? -46.133 -8.536 50.487 1.00 21.86 ? 337 LEU A N 1 ATOM 2358 C CA . LEU A 1 317 ? -47.328 -9.276 50.128 1.00 21.18 ? 337 LEU A CA 1 ATOM 2359 C C . LEU A 1 317 ? -47.978 -8.749 48.861 1.00 20.74 ? 337 LEU A C 1 ATOM 2360 O O . LEU A 1 317 ? -47.858 -7.572 48.539 1.00 20.87 ? 337 LEU A O 1 ATOM 2361 C CB . LEU A 1 317 ? -48.312 -9.223 51.298 1.00 21.16 ? 337 LEU A CB 1 ATOM 2362 C CG . LEU A 1 317 ? -47.752 -10.002 52.497 1.00 22.11 ? 337 LEU A CG 1 ATOM 2363 C CD1 . LEU A 1 317 ? -47.832 -9.181 53.763 1.00 22.37 ? 337 LEU A CD1 1 ATOM 2364 C CD2 . LEU A 1 317 ? -48.446 -11.338 52.640 1.00 21.75 ? 337 LEU A CD2 1 ATOM 2365 N N . ASN A 1 318 ? -48.663 -9.645 48.149 1.00 20.42 ? 338 ASN A N 1 ATOM 2366 C CA . ASN A 1 318 ? -49.508 -9.295 47.006 1.00 19.70 ? 338 ASN A CA 1 ATOM 2367 C C . ASN A 1 318 ? -48.721 -8.542 45.938 1.00 19.18 ? 338 ASN A C 1 ATOM 2368 O O . ASN A 1 318 ? -49.178 -7.549 45.381 1.00 19.23 ? 338 ASN A O 1 ATOM 2369 C CB . ASN A 1 318 ? -50.722 -8.495 47.484 1.00 19.91 ? 338 ASN A CB 1 ATOM 2370 C CG . ASN A 1 318 ? -51.787 -8.361 46.416 1.00 19.93 ? 338 ASN A CG 1 ATOM 2371 O OD1 . ASN A 1 318 ? -52.038 -9.302 45.659 1.00 20.14 ? 338 ASN A OD1 1 ATOM 2372 N ND2 . ASN A 1 318 ? -52.405 -7.188 46.335 1.00 18.29 ? 338 ASN A ND2 1 ATOM 2373 N N . VAL A 1 319 ? -47.521 -9.049 45.660 1.00 18.72 ? 339 VAL A N 1 ATOM 2374 C CA . VAL A 1 319 ? -46.576 -8.395 44.784 1.00 17.87 ? 339 VAL A CA 1 ATOM 2375 C C . VAL A 1 319 ? -47.010 -8.558 43.336 1.00 18.03 ? 339 VAL A C 1 ATOM 2376 O O . VAL A 1 319 ? -47.108 -9.682 42.838 1.00 17.30 ? 339 VAL A O 1 ATOM 2377 C CB . VAL A 1 319 ? -45.158 -8.982 44.956 1.00 18.07 ? 339 VAL A CB 1 ATOM 2378 C CG1 . VAL A 1 319 ? -44.173 -8.292 44.019 1.00 17.64 ? 339 VAL A CG1 1 ATOM 2379 C CG2 . VAL A 1 319 ? -44.688 -8.877 46.424 1.00 16.01 ? 339 VAL A CG2 1 ATOM 2380 N N . HIS A 1 320 ? -47.257 -7.425 42.673 1.00 18.12 ? 340 HIS A N 1 ATOM 2381 C CA . HIS A 1 320 ? -47.552 -7.378 41.247 1.00 18.08 ? 340 HIS A CA 1 ATOM 2382 C C . HIS A 1 320 ? -46.457 -6.624 40.502 1.00 18.52 ? 340 HIS A C 1 ATOM 2383 O O . HIS A 1 320 ? -45.799 -5.746 41.065 1.00 17.79 ? 340 HIS A O 1 ATOM 2384 C CB . HIS A 1 320 ? -48.855 -6.623 40.974 1.00 17.80 ? 340 HIS A CB 1 ATOM 2385 C CG . HIS A 1 320 ? -50.094 -7.315 41.446 1.00 17.79 ? 340 HIS A CG 1 ATOM 2386 N ND1 . HIS A 1 320 ? -50.331 -7.605 42.771 1.00 17.81 ? 340 HIS A ND1 1 ATOM 2387 C CD2 . HIS A 1 320 ? -51.192 -7.730 40.768 1.00 18.16 ? 340 HIS A CD2 1 ATOM 2388 C CE1 . HIS A 1 320 ? -51.512 -8.188 42.886 1.00 18.49 ? 340 HIS A CE1 1 ATOM 2389 N NE2 . HIS A 1 320 ? -52.054 -8.277 41.686 1.00 17.71 ? 340 HIS A NE2 1 ATOM 2390 N N . PHE A 1 321 ? -46.281 -6.984 39.233 1.00 19.17 ? 341 PHE A N 1 ATOM 2391 C CA . PHE A 1 321 ? -45.626 -6.129 38.264 1.00 20.46 ? 341 PHE A CA 1 ATOM 2392 C C . PHE A 1 321 ? -46.474 -6.105 36.997 1.00 21.35 ? 341 PHE A C 1 ATOM 2393 O O . PHE A 1 321 ? -46.969 -7.141 36.573 1.00 21.86 ? 341 PHE A O 1 ATOM 2394 C CB . PHE A 1 321 ? -44.209 -6.605 37.957 1.00 20.41 ? 341 PHE A CB 1 ATOM 2395 C CG . PHE A 1 321 ? -43.403 -5.607 37.197 1.00 21.23 ? 341 PHE A CG 1 ATOM 2396 C CD1 . PHE A 1 321 ? -42.462 -4.818 37.842 1.00 21.67 ? 341 PHE A CD1 1 ATOM 2397 C CD2 . PHE A 1 321 ? -43.621 -5.406 35.835 1.00 24.17 ? 341 PHE A CD2 1 ATOM 2398 C CE1 . PHE A 1 321 ? -41.710 -3.871 37.133 1.00 21.94 ? 341 PHE A CE1 1 ATOM 2399 C CE2 . PHE A 1 321 ? -42.887 -4.449 35.124 1.00 24.30 ? 341 PHE A CE2 1 ATOM 2400 C CZ . PHE A 1 321 ? -41.916 -3.693 35.778 1.00 23.01 ? 341 PHE A CZ 1 ATOM 2401 N N . GLY A 1 322 ? -46.661 -4.918 36.425 1.00 22.10 ? 342 GLY A N 1 ATOM 2402 C CA . GLY A 1 322 ? -47.481 -4.739 35.231 1.00 22.74 ? 342 GLY A CA 1 ATOM 2403 C C . GLY A 1 322 ? -48.969 -5.003 35.428 1.00 23.26 ? 342 GLY A C 1 ATOM 2404 O O . GLY A 1 322 ? -49.690 -5.256 34.465 1.00 23.17 ? 342 GLY A O 1 ATOM 2405 N N . GLY A 1 323 ? -49.435 -4.931 36.668 1.00 23.82 ? 343 GLY A N 1 ATOM 2406 C CA . GLY A 1 323 ? -50.819 -5.273 36.982 1.00 24.11 ? 343 GLY A CA 1 ATOM 2407 C C . GLY A 1 323 ? -51.077 -6.767 37.072 1.00 24.39 ? 343 GLY A C 1 ATOM 2408 O O . GLY A 1 323 ? -52.229 -7.193 37.125 1.00 25.00 ? 343 GLY A O 1 ATOM 2409 N N . GLU A 1 324 ? -50.019 -7.572 37.097 1.00 23.95 ? 344 GLU A N 1 ATOM 2410 C CA . GLU A 1 324 ? -50.176 -9.009 37.249 1.00 24.00 ? 344 GLU A CA 1 ATOM 2411 C C . GLU A 1 324 ? -49.408 -9.523 38.460 1.00 23.07 ? 344 GLU A C 1 ATOM 2412 O O . GLU A 1 324 ? -48.271 -9.103 38.719 1.00 22.30 ? 344 GLU A O 1 ATOM 2413 C CB . GLU A 1 324 ? -49.733 -9.704 35.978 1.00 24.56 ? 344 GLU A CB 1 ATOM 2414 C CG . GLU A 1 324 ? -50.443 -9.126 34.761 1.00 26.91 ? 344 GLU A CG 1 ATOM 2415 C CD . GLU A 1 324 ? -50.245 -9.955 33.544 1.00 29.39 ? 344 GLU A CD 1 ATOM 2416 O OE1 . GLU A 1 324 ? -49.505 -9.515 32.636 1.00 33.33 ? 344 GLU A OE1 1 ATOM 2417 O OE2 . GLU A 1 324 ? -50.824 -11.052 33.497 1.00 32.13 ? 344 GLU A OE2 1 ATOM 2418 N N . ARG A 1 325 ? -50.041 -10.424 39.207 1.00 22.16 ? 345 ARG A N 1 ATOM 2419 C CA . ARG A 1 325 ? -49.429 -10.969 40.410 1.00 21.62 ? 345 ARG A CA 1 ATOM 2420 C C . ARG A 1 325 ? -48.228 -11.841 40.057 1.00 21.26 ? 345 ARG A C 1 ATOM 2421 O O . ARG A 1 325 ? -48.224 -12.567 39.057 1.00 19.85 ? 345 ARG A O 1 ATOM 2422 C CB . ARG A 1 325 ? -50.430 -11.760 41.259 1.00 21.75 ? 345 ARG A CB 1 ATOM 2423 C CG . ARG A 1 325 ? -49.876 -12.140 42.634 1.00 22.04 ? 345 ARG A CG 1 ATOM 2424 C CD . ARG A 1 325 ? -50.941 -12.717 43.574 1.00 22.45 ? 345 ARG A CD 1 ATOM 2425 N NE . ARG A 1 325 ? -51.922 -11.708 43.995 1.00 23.85 ? 345 ARG A NE 1 ATOM 2426 C CZ . ARG A 1 325 ? -53.221 -11.702 43.670 1.00 23.58 ? 345 ARG A CZ 1 ATOM 2427 N NH1 . ARG A 1 325 ? -53.748 -12.662 42.925 1.00 23.79 ? 345 ARG A NH1 1 ATOM 2428 N NH2 . ARG A 1 325 ? -54.008 -10.726 44.104 1.00 23.11 ? 345 ARG A NH2 1 ATOM 2429 N N . ILE A 1 326 ? -47.215 -11.729 40.900 1.00 20.80 ? 346 ILE A N 1 ATOM 2430 C CA . ILE A 1 326 ? -45.997 -12.517 40.812 1.00 21.45 ? 346 ILE A CA 1 ATOM 2431 C C . ILE A 1 326 ? -45.813 -13.376 42.068 1.00 20.95 ? 346 ILE A C 1 ATOM 2432 O O . ILE A 1 326 ? -45.478 -14.562 41.963 1.00 20.88 ? 346 ILE A O 1 ATOM 2433 C CB . ILE A 1 326 ? -44.806 -11.584 40.650 1.00 21.78 ? 346 ILE A CB 1 ATOM 2434 C CG1 . ILE A 1 326 ? -44.873 -10.928 39.269 1.00 23.79 ? 346 ILE A CG1 1 ATOM 2435 C CG2 . ILE A 1 326 ? -43.501 -12.331 40.823 1.00 23.06 ? 346 ILE A CG2 1 ATOM 2436 C CD1 . ILE A 1 326 ? -43.970 -9.733 39.152 1.00 27.08 ? 346 ILE A CD1 1 ATOM 2437 N N . ALA A 1 327 ? -46.046 -12.777 43.240 1.00 20.09 ? 347 ALA A N 1 ATOM 2438 C CA . ALA A 1 327 ? -45.904 -13.462 44.531 1.00 20.11 ? 347 ALA A CA 1 ATOM 2439 C C . ALA A 1 327 ? -46.956 -13.001 45.546 1.00 19.96 ? 347 ALA A C 1 ATOM 2440 O O . ALA A 1 327 ? -47.123 -11.806 45.775 1.00 19.90 ? 347 ALA A O 1 ATOM 2441 C CB . ALA A 1 327 ? -44.506 -13.207 45.100 1.00 19.89 ? 347 ALA A CB 1 ATOM 2442 N N . TYR A 1 328 ? -47.647 -13.948 46.177 1.00 19.83 ? 348 TYR A N 1 ATOM 2443 C CA . TYR A 1 328 ? -48.581 -13.605 47.251 1.00 19.52 ? 348 TYR A CA 1 ATOM 2444 C C . TYR A 1 328 ? -47.854 -13.188 48.529 1.00 19.34 ? 348 TYR A C 1 ATOM 2445 O O . TYR A 1 328 ? -48.345 -12.324 49.263 1.00 18.87 ? 348 TYR A O 1 ATOM 2446 C CB . TYR A 1 328 ? -49.531 -14.765 47.554 1.00 19.82 ? 348 TYR A CB 1 ATOM 2447 C CG . TYR A 1 328 ? -50.583 -14.410 48.575 1.00 19.49 ? 348 TYR A CG 1 ATOM 2448 C CD1 . TYR A 1 328 ? -51.676 -13.636 48.218 1.00 20.13 ? 348 TYR A CD1 1 ATOM 2449 C CD2 . TYR A 1 328 ? -50.478 -14.834 49.899 1.00 19.38 ? 348 TYR A CD2 1 ATOM 2450 C CE1 . TYR A 1 328 ? -52.654 -13.300 49.149 1.00 19.86 ? 348 TYR A CE1 1 ATOM 2451 C CE2 . TYR A 1 328 ? -51.447 -14.505 50.838 1.00 18.83 ? 348 TYR A CE2 1 ATOM 2452 C CZ . TYR A 1 328 ? -52.536 -13.729 50.449 1.00 20.04 ? 348 TYR A CZ 1 ATOM 2453 O OH . TYR A 1 328 ? -53.513 -13.369 51.345 1.00 21.60 ? 348 TYR A OH 1 ATOM 2454 N N . GLU A 1 329 ? -46.691 -13.801 48.790 1.00 19.05 ? 349 GLU A N 1 ATOM 2455 C CA . GLU A 1 329 ? -45.912 -13.538 50.001 1.00 18.04 ? 349 GLU A CA 1 ATOM 2456 C C . GLU A 1 329 ? -44.449 -13.890 49.783 1.00 17.81 ? 349 GLU A C 1 ATOM 2457 O O . GLU A 1 329 ? -44.123 -14.908 49.159 1.00 18.12 ? 349 GLU A O 1 ATOM 2458 C CB . GLU A 1 329 ? -46.457 -14.367 51.169 1.00 18.53 ? 349 GLU A CB 1 ATOM 2459 C CG . GLU A 1 329 ? -45.750 -14.150 52.540 1.00 18.53 ? 349 GLU A CG 1 ATOM 2460 C CD . GLU A 1 329 ? -46.010 -15.283 53.526 1.00 20.16 ? 349 GLU A CD 1 ATOM 2461 O OE1 . GLU A 1 329 ? -46.859 -16.145 53.220 1.00 21.39 ? 349 GLU A OE1 1 ATOM 2462 O OE2 . GLU A 1 329 ? -45.363 -15.328 54.601 1.00 19.59 ? 349 GLU A OE2 1 ATOM 2463 N N . VAL A 1 330 ? -43.571 -13.025 50.266 1.00 17.01 ? 350 VAL A N 1 ATOM 2464 C CA . VAL A 1 330 ? -42.167 -13.336 50.424 1.00 17.11 ? 350 VAL A CA 1 ATOM 2465 C C . VAL A 1 330 ? -41.824 -12.866 51.831 1.00 17.22 ? 350 VAL A C 1 ATOM 2466 O O . VAL A 1 330 ? -42.020 -11.690 52.154 1.00 16.63 ? 350 VAL A O 1 ATOM 2467 C CB . VAL A 1 330 ? -41.280 -12.614 49.387 1.00 17.38 ? 350 VAL A CB 1 ATOM 2468 C CG1 . VAL A 1 330 ? -39.858 -13.171 49.425 1.00 16.58 ? 350 VAL A CG1 1 ATOM 2469 C CG2 . VAL A 1 330 ? -41.882 -12.735 47.977 1.00 16.50 ? 350 VAL A CG2 1 ATOM 2470 N N . SER A 1 331 ? -41.352 -13.782 52.675 1.00 17.09 ? 351 SER A N 1 ATOM 2471 C CA . SER A 1 331 ? -41.145 -13.466 54.076 1.00 16.82 ? 351 SER A CA 1 ATOM 2472 C C . SER A 1 331 ? -39.989 -14.230 54.695 1.00 16.70 ? 351 SER A C 1 ATOM 2473 O O . SER A 1 331 ? -39.725 -15.387 54.348 1.00 16.47 ? 351 SER A O 1 ATOM 2474 C CB . SER A 1 331 ? -42.418 -13.755 54.866 1.00 17.07 ? 351 SER A CB 1 ATOM 2475 O OG . SER A 1 331 ? -42.836 -15.098 54.688 1.00 17.54 ? 351 SER A OG 1 ATOM 2476 N N . VAL A 1 332 ? -39.316 -13.560 55.625 1.00 16.35 ? 352 VAL A N 1 ATOM 2477 C CA . VAL A 1 332 ? -38.339 -14.182 56.500 1.00 16.93 ? 352 VAL A CA 1 ATOM 2478 C C . VAL A 1 332 ? -39.086 -15.136 57.435 1.00 16.76 ? 352 VAL A C 1 ATOM 2479 O O . VAL A 1 332 ? -40.123 -14.780 58.015 1.00 16.16 ? 352 VAL A O 1 ATOM 2480 C CB . VAL A 1 332 ? -37.558 -13.117 57.328 1.00 17.25 ? 352 VAL A CB 1 ATOM 2481 C CG1 . VAL A 1 332 ? -36.418 -13.759 58.132 1.00 17.55 ? 352 VAL A CG1 1 ATOM 2482 C CG2 . VAL A 1 332 ? -37.015 -12.009 56.400 1.00 18.09 ? 352 VAL A CG2 1 ATOM 2483 N N . GLN A 1 333 ? -38.578 -16.363 57.538 1.00 16.80 ? 353 GLN A N 1 ATOM 2484 C CA . GLN A 1 333 ? -39.179 -17.392 58.383 1.00 17.17 ? 353 GLN A CA 1 ATOM 2485 C C . GLN A 1 333 ? -38.359 -17.711 59.632 1.00 17.61 ? 353 GLN A C 1 ATOM 2486 O O . GLN A 1 333 ? -38.917 -17.972 60.693 1.00 18.15 ? 353 GLN A O 1 ATOM 2487 C CB . GLN A 1 333 ? -39.375 -18.663 57.557 1.00 17.16 ? 353 GLN A CB 1 ATOM 2488 C CG . GLN A 1 333 ? -40.456 -18.515 56.487 1.00 16.87 ? 353 GLN A CG 1 ATOM 2489 C CD . GLN A 1 333 ? -41.834 -18.325 57.091 1.00 16.36 ? 353 GLN A CD 1 ATOM 2490 O OE1 . GLN A 1 333 ? -42.207 -19.047 58.012 1.00 16.75 ? 353 GLN A OE1 1 ATOM 2491 N NE2 . GLN A 1 333 ? -42.603 -17.366 56.567 1.00 15.98 ? 353 GLN A NE2 1 ATOM 2492 N N . GLU A 1 334 ? -37.036 -17.729 59.496 1.00 17.92 ? 354 GLU A N 1 ATOM 2493 C CA . GLU A 1 334 ? -36.144 -18.044 60.610 1.00 18.32 ? 354 GLU A CA 1 ATOM 2494 C C . GLU A 1 334 ? -34.730 -17.618 60.231 1.00 18.32 ? 354 GLU A C 1 ATOM 2495 O O . GLU A 1 334 ? -34.397 -17.527 59.054 1.00 17.92 ? 354 GLU A O 1 ATOM 2496 C CB . GLU A 1 334 ? -36.184 -19.543 60.939 1.00 18.43 ? 354 GLU A CB 1 ATOM 2497 C CG . GLU A 1 334 ? -35.383 -19.979 62.194 1.00 19.39 ? 354 GLU A CG 1 ATOM 2498 C CD . GLU A 1 334 ? -35.782 -19.227 63.450 1.00 20.41 ? 354 GLU A CD 1 ATOM 2499 O OE1 . GLU A 1 334 ? -36.629 -19.743 64.219 1.00 22.13 ? 354 GLU A OE1 1 ATOM 2500 O OE2 . GLU A 1 334 ? -35.268 -18.108 63.652 1.00 19.55 ? 354 GLU A OE2 1 ATOM 2501 N N . ALA A 1 335 ? -33.920 -17.327 61.238 1.00 18.85 ? 355 ALA A N 1 ATOM 2502 C CA . ALA A 1 335 ? -32.515 -16.962 61.033 1.00 18.82 ? 355 ALA A CA 1 ATOM 2503 C C . ALA A 1 335 ? -31.732 -17.536 62.196 1.00 18.93 ? 355 ALA A C 1 ATOM 2504 O O . ALA A 1 335 ? -32.058 -17.265 63.351 1.00 18.94 ? 355 ALA A O 1 ATOM 2505 C CB . ALA A 1 335 ? -32.352 -15.469 60.963 1.00 18.49 ? 355 ALA A CB 1 ATOM 2506 N N . VAL A 1 336 ? -30.715 -18.337 61.886 1.00 18.55 ? 356 VAL A N 1 ATOM 2507 C CA . VAL A 1 336 ? -30.031 -19.129 62.895 1.00 18.73 ? 356 VAL A CA 1 ATOM 2508 C C . VAL A 1 336 ? -28.525 -18.949 62.794 1.00 18.95 ? 356 VAL A C 1 ATOM 2509 O O . VAL A 1 336 ? -27.992 -18.604 61.725 1.00 18.89 ? 356 VAL A O 1 ATOM 2510 C CB . VAL A 1 336 ? -30.376 -20.653 62.782 1.00 18.69 ? 356 VAL A CB 1 ATOM 2511 C CG1 . VAL A 1 336 ? -31.877 -20.873 62.643 1.00 18.28 ? 356 VAL A CG1 1 ATOM 2512 C CG2 . VAL A 1 336 ? -29.651 -21.296 61.617 1.00 18.80 ? 356 VAL A CG2 1 ATOM 2513 N N . ALA A 1 337 ? -27.862 -19.172 63.920 1.00 18.48 ? 357 ALA A N 1 ATOM 2514 C CA . ALA A 1 337 ? -26.421 -19.153 64.009 1.00 18.89 ? 357 ALA A CA 1 ATOM 2515 C C . ALA A 1 337 ? -26.012 -20.373 64.837 1.00 19.06 ? 357 ALA A C 1 ATOM 2516 O O . ALA A 1 337 ? -26.336 -20.466 66.030 1.00 19.67 ? 357 ALA A O 1 ATOM 2517 C CB . ALA A 1 337 ? -25.926 -17.825 64.639 1.00 18.62 ? 357 ALA A CB 1 ATOM 2518 N N . LEU A 1 338 ? -25.339 -21.323 64.189 1.00 18.96 ? 358 LEU A N 1 ATOM 2519 C CA . LEU A 1 338 ? -25.072 -22.631 64.778 1.00 19.00 ? 358 LEU A CA 1 ATOM 2520 C C . LEU A 1 338 ? -23.600 -22.723 65.103 1.00 19.05 ? 358 LEU A C 1 ATOM 2521 O O . LEU A 1 338 ? -22.769 -22.680 64.193 1.00 18.96 ? 358 LEU A O 1 ATOM 2522 C CB . LEU A 1 338 ? -25.455 -23.735 63.793 1.00 18.82 ? 358 LEU A CB 1 ATOM 2523 C CG . LEU A 1 338 ? -26.882 -23.683 63.237 1.00 20.03 ? 358 LEU A CG 1 ATOM 2524 C CD1 . LEU A 1 338 ? -27.133 -24.803 62.212 1.00 19.73 ? 358 LEU A CD1 1 ATOM 2525 C CD2 . LEU A 1 338 ? -27.908 -23.744 64.387 1.00 19.82 ? 358 LEU A CD2 1 ATOM 2526 N N . TYR A 1 339 ? -23.280 -22.868 66.386 1.00 19.13 ? 359 TYR A N 1 ATOM 2527 C CA . TYR A 1 339 ? -21.907 -22.718 66.858 1.00 19.72 ? 359 TYR A CA 1 ATOM 2528 C C . TYR A 1 339 ? -21.229 -24.022 67.196 1.00 20.15 ? 359 TYR A C 1 ATOM 2529 O O . TYR A 1 339 ? -21.882 -25.024 67.490 1.00 20.43 ? 359 TYR A O 1 ATOM 2530 C CB . TYR A 1 339 ? -21.881 -21.803 68.095 1.00 19.97 ? 359 TYR A CB 1 ATOM 2531 C CG . TYR A 1 339 ? -22.197 -20.370 67.728 1.00 19.21 ? 359 TYR A CG 1 ATOM 2532 C CD1 . TYR A 1 339 ? -21.171 -19.458 67.499 1.00 17.39 ? 359 TYR A CD1 1 ATOM 2533 C CD2 . TYR A 1 339 ? -23.511 -19.948 67.548 1.00 18.40 ? 359 TYR A CD2 1 ATOM 2534 C CE1 . TYR A 1 339 ? -21.437 -18.166 67.121 1.00 17.82 ? 359 TYR A CE1 1 ATOM 2535 C CE2 . TYR A 1 339 ? -23.796 -18.640 67.170 1.00 18.61 ? 359 TYR A CE2 1 ATOM 2536 C CZ . TYR A 1 339 ? -22.754 -17.757 66.953 1.00 18.46 ? 359 TYR A CZ 1 ATOM 2537 O OH . TYR A 1 339 ? -23.004 -16.464 66.582 1.00 19.56 ? 359 TYR A OH 1 ATOM 2538 N N . GLY A 1 340 ? -19.901 -23.990 67.153 1.00 20.95 ? 360 GLY A N 1 ATOM 2539 C CA . GLY A 1 340 ? -19.072 -24.993 67.816 1.00 21.51 ? 360 GLY A CA 1 ATOM 2540 C C . GLY A 1 340 ? -18.274 -24.259 68.871 1.00 22.16 ? 360 GLY A C 1 ATOM 2541 O O . GLY A 1 340 ? -18.138 -23.029 68.799 1.00 22.06 ? 360 GLY A O 1 ATOM 2542 N N . GLY A 1 341 ? -17.756 -24.987 69.858 1.00 22.83 ? 361 GLY A N 1 ATOM 2543 C CA . GLY A 1 341 ? -16.916 -24.362 70.871 1.00 23.41 ? 361 GLY A CA 1 ATOM 2544 C C . GLY A 1 341 ? -16.147 -25.291 71.796 1.00 24.11 ? 361 GLY A C 1 ATOM 2545 O O . GLY A 1 341 ? -16.491 -26.462 71.974 1.00 24.25 ? 361 GLY A O 1 ATOM 2546 N N . HIS A 1 342 ? -15.110 -24.721 72.402 1.00 24.76 ? 362 HIS A N 1 ATOM 2547 C CA . HIS A 1 342 ? -14.317 -25.377 73.434 1.00 25.27 ? 362 HIS A CA 1 ATOM 2548 C C . HIS A 1 342 ? -14.951 -25.230 74.819 1.00 25.08 ? 362 HIS A C 1 ATOM 2549 O O . HIS A 1 342 ? -14.782 -26.097 75.677 1.00 25.23 ? 362 HIS A O 1 ATOM 2550 C CB . HIS A 1 342 ? -12.890 -24.816 73.442 1.00 25.71 ? 362 HIS A CB 1 ATOM 2551 C CG . HIS A 1 342 ? -12.802 -23.349 73.755 1.00 28.14 ? 362 HIS A CG 1 ATOM 2552 N ND1 . HIS A 1 342 ? -13.372 -22.375 72.958 1.00 30.27 ? 362 HIS A ND1 1 ATOM 2553 C CD2 . HIS A 1 342 ? -12.181 -22.688 74.763 1.00 30.61 ? 362 HIS A CD2 1 ATOM 2554 C CE1 . HIS A 1 342 ? -13.138 -21.183 73.480 1.00 30.13 ? 362 HIS A CE1 1 ATOM 2555 N NE2 . HIS A 1 342 ? -12.407 -21.344 74.570 1.00 30.82 ? 362 HIS A NE2 1 ATOM 2556 N N . THR A 1 343 ? -15.665 -24.133 75.050 1.00 24.79 ? 363 THR A N 1 ATOM 2557 C CA . THR A 1 343 ? -16.351 -23.940 76.325 1.00 24.30 ? 363 THR A CA 1 ATOM 2558 C C . THR A 1 343 ? -17.745 -24.562 76.231 1.00 24.28 ? 363 THR A C 1 ATOM 2559 O O . THR A 1 343 ? -18.254 -24.740 75.124 1.00 24.45 ? 363 THR A O 1 ATOM 2560 C CB . THR A 1 343 ? -16.446 -22.449 76.716 1.00 24.41 ? 363 THR A CB 1 ATOM 2561 O OG1 . THR A 1 343 ? -17.495 -21.803 75.979 1.00 23.37 ? 363 THR A OG1 1 ATOM 2562 C CG2 . THR A 1 343 ? -15.121 -21.743 76.473 1.00 23.20 ? 363 THR A CG2 1 ATOM 2563 N N . PRO A 1 344 ? -18.361 -24.902 77.383 1.00 24.01 ? 364 PRO A N 1 ATOM 2564 C CA . PRO A 1 344 ? -19.720 -25.473 77.389 1.00 23.78 ? 364 PRO A CA 1 ATOM 2565 C C . PRO A 1 344 ? -20.786 -24.565 76.750 1.00 23.59 ? 364 PRO A C 1 ATOM 2566 O O . PRO A 1 344 ? -21.667 -25.057 76.031 1.00 23.41 ? 364 PRO A O 1 ATOM 2567 C CB . PRO A 1 344 ? -20.029 -25.681 78.884 1.00 24.13 ? 364 PRO A CB 1 ATOM 2568 C CG . PRO A 1 344 ? -18.735 -25.584 79.594 1.00 24.12 ? 364 PRO A CG 1 ATOM 2569 C CD . PRO A 1 344 ? -17.793 -24.799 78.743 1.00 24.17 ? 364 PRO A CD 1 ATOM 2570 N N . ALA A 1 345 ? -20.704 -23.261 77.016 1.00 23.12 ? 365 ALA A N 1 ATOM 2571 C CA . ALA A 1 345 ? -21.604 -22.282 76.397 1.00 23.10 ? 365 ALA A CA 1 ATOM 2572 C C . ALA A 1 345 ? -21.459 -22.292 74.885 1.00 22.92 ? 365 ALA A C 1 ATOM 2573 O O . ALA A 1 345 ? -22.452 -22.241 74.164 1.00 22.54 ? 365 ALA A O 1 ATOM 2574 C CB . ALA A 1 345 ? -21.331 -20.875 76.932 1.00 22.86 ? 365 ALA A CB 1 ATOM 2575 N N . GLY A 1 346 ? -20.215 -22.356 74.417 1.00 22.88 ? 366 GLY A N 1 ATOM 2576 C CA . GLY A 1 346 ? -19.924 -22.346 72.994 1.00 23.06 ? 366 GLY A CA 1 ATOM 2577 C C . GLY A 1 346 ? -20.444 -23.573 72.287 1.00 23.00 ? 366 GLY A C 1 ATOM 2578 O O . GLY A 1 346 ? -21.074 -23.471 71.237 1.00 23.21 ? 366 GLY A O 1 ATOM 2579 N N . MET A 1 347 ? -20.197 -24.744 72.863 1.00 23.37 ? 367 MET A N 1 ATOM 2580 C CA . MET A 1 347 ? -20.697 -25.982 72.270 1.00 23.25 ? 367 MET A CA 1 ATOM 2581 C C . MET A 1 347 ? -22.223 -26.157 72.440 1.00 22.71 ? 367 MET A C 1 ATOM 2582 O O . MET A 1 347 ? -22.829 -27.009 71.796 1.00 22.59 ? 367 MET A O 1 ATOM 2583 C CB . MET A 1 347 ? -19.891 -27.202 72.746 1.00 23.54 ? 367 MET A CB 1 ATOM 2584 C CG . MET A 1 347 ? -19.961 -27.571 74.208 1.00 25.39 ? 367 MET A CG 1 ATOM 2585 S SD . MET A 1 347 ? -18.914 -29.010 74.585 1.00 27.17 ? 367 MET A SD 1 ATOM 2586 C CE . MET A 1 347 ? -17.257 -28.317 74.561 1.00 26.15 ? 367 MET A CE 1 ATOM 2587 N N . GLN A 1 348 ? -22.846 -25.323 73.267 1.00 22.04 ? 368 GLN A N 1 ATOM 2588 C CA . GLN A 1 348 ? -24.294 -25.357 73.453 1.00 21.54 ? 368 GLN A CA 1 ATOM 2589 C C . GLN A 1 348 ? -25.048 -24.515 72.416 1.00 21.36 ? 368 GLN A C 1 ATOM 2590 O O . GLN A 1 348 ? -26.220 -24.770 72.141 1.00 21.25 ? 368 GLN A O 1 ATOM 2591 C CB . GLN A 1 348 ? -24.647 -24.829 74.848 1.00 21.50 ? 368 GLN A CB 1 ATOM 2592 C CG . GLN A 1 348 ? -26.115 -24.998 75.245 1.00 21.26 ? 368 GLN A CG 1 ATOM 2593 C CD . GLN A 1 348 ? -26.497 -26.447 75.390 1.00 20.41 ? 368 GLN A CD 1 ATOM 2594 O OE1 . GLN A 1 348 ? -25.636 -27.297 75.619 1.00 20.99 ? 368 GLN A OE1 1 ATOM 2595 N NE2 . GLN A 1 348 ? -27.786 -26.743 75.264 1.00 20.31 ? 368 GLN A NE2 1 ATOM 2596 N N . THR A 1 349 ? -24.387 -23.501 71.858 1.00 21.36 ? 369 THR A N 1 ATOM 2597 C CA . THR A 1 349 ? -25.106 -22.419 71.172 1.00 21.08 ? 369 THR A CA 1 ATOM 2598 C C . THR A 1 349 ? -25.640 -22.763 69.789 1.00 21.26 ? 369 THR A C 1 ATOM 2599 O O . THR A 1 349 ? -24.886 -22.909 68.831 1.00 21.28 ? 369 THR A O 1 ATOM 2600 C CB . THR A 1 349 ? -24.264 -21.146 71.044 1.00 20.88 ? 369 THR A CB 1 ATOM 2601 O OG1 . THR A 1 349 ? -23.772 -20.773 72.336 1.00 20.86 ? 369 THR A OG1 1 ATOM 2602 C CG2 . THR A 1 349 ? -25.112 -20.004 70.444 1.00 19.57 ? 369 THR A CG2 1 ATOM 2603 N N . LYS A 1 350 ? -26.958 -22.878 69.709 1.00 21.53 ? 370 LYS A N 1 ATOM 2604 C CA . LYS A 1 350 ? -27.660 -22.862 68.440 1.00 21.83 ? 370 LYS A CA 1 ATOM 2605 C C . LYS A 1 350 ? -28.758 -21.821 68.549 1.00 21.57 ? 370 LYS A C 1 ATOM 2606 O O . LYS A 1 350 ? -29.857 -22.111 69.017 1.00 21.30 ? 370 LYS A O 1 ATOM 2607 C CB . LYS A 1 350 ? -28.251 -24.235 68.124 1.00 22.29 ? 370 LYS A CB 1 ATOM 2608 C CG . LYS A 1 350 ? -27.237 -25.344 68.057 1.00 24.24 ? 370 LYS A CG 1 ATOM 2609 C CD . LYS A 1 350 ? -27.919 -26.689 67.937 1.00 26.77 ? 370 LYS A CD 1 ATOM 2610 C CE . LYS A 1 350 ? -26.910 -27.801 67.756 1.00 27.67 ? 370 LYS A CE 1 ATOM 2611 N NZ . LYS A 1 350 ? -26.111 -28.010 68.982 1.00 28.77 ? 370 LYS A NZ 1 ATOM 2612 N N . TYR A 1 351 ? -28.455 -20.596 68.137 1.00 21.53 ? 371 TYR A N 1 ATOM 2613 C CA . TYR A 1 351 ? -29.431 -19.517 68.243 1.00 21.81 ? 371 TYR A CA 1 ATOM 2614 C C . TYR A 1 351 ? -30.461 -19.569 67.107 1.00 21.87 ? 371 TYR A C 1 ATOM 2615 O O . TYR A 1 351 ? -30.086 -19.570 65.935 1.00 21.55 ? 371 TYR A O 1 ATOM 2616 C CB . TYR A 1 351 ? -28.746 -18.154 68.228 1.00 21.80 ? 371 TYR A CB 1 ATOM 2617 C CG . TYR A 1 351 ? -28.096 -17.726 69.523 1.00 21.84 ? 371 TYR A CG 1 ATOM 2618 C CD1 . TYR A 1 351 ? -28.790 -17.788 70.729 1.00 22.66 ? 371 TYR A CD1 1 ATOM 2619 C CD2 . TYR A 1 351 ? -26.810 -17.196 69.530 1.00 21.65 ? 371 TYR A CD2 1 ATOM 2620 C CE1 . TYR A 1 351 ? -28.207 -17.370 71.916 1.00 23.00 ? 371 TYR A CE1 1 ATOM 2621 C CE2 . TYR A 1 351 ? -26.214 -16.769 70.714 1.00 23.44 ? 371 TYR A CE2 1 ATOM 2622 C CZ . TYR A 1 351 ? -26.918 -16.868 71.905 1.00 22.59 ? 371 TYR A CZ 1 ATOM 2623 O OH . TYR A 1 351 ? -26.348 -16.446 73.080 1.00 24.12 ? 371 TYR A OH 1 ATOM 2624 N N . LEU A 1 352 ? -31.744 -19.601 67.473 1.00 21.88 ? 372 LEU A N 1 ATOM 2625 C CA . LEU A 1 352 ? -32.863 -19.461 66.529 1.00 22.24 ? 372 LEU A CA 1 ATOM 2626 C C . LEU A 1 352 ? -33.598 -18.152 66.828 1.00 22.24 ? 372 LEU A C 1 ATOM 2627 O O . LEU A 1 352 ? -34.333 -18.058 67.812 1.00 22.03 ? 372 LEU A O 1 ATOM 2628 C CB . LEU A 1 352 ? -33.833 -20.633 66.655 1.00 22.08 ? 372 LEU A CB 1 ATOM 2629 C CG . LEU A 1 352 ? -33.453 -21.896 65.898 1.00 23.60 ? 372 LEU A CG 1 ATOM 2630 C CD1 . LEU A 1 352 ? -32.151 -22.477 66.416 1.00 22.35 ? 372 LEU A CD1 1 ATOM 2631 C CD2 . LEU A 1 352 ? -34.601 -22.919 65.969 1.00 23.54 ? 372 LEU A CD2 1 ATOM 2632 N N . ASP A 1 353 ? -33.423 -17.154 65.967 1.00 22.21 ? 373 ASP A N 1 ATOM 2633 C CA . ASP A 1 353 ? -33.775 -15.781 66.328 1.00 22.86 ? 373 ASP A CA 1 ATOM 2634 C C . ASP A 1 353 ? -35.265 -15.450 66.408 1.00 22.51 ? 373 ASP A C 1 ATOM 2635 O O . ASP A 1 353 ? -35.633 -14.520 67.115 1.00 22.27 ? 373 ASP A O 1 ATOM 2636 C CB . ASP A 1 353 ? -33.053 -14.795 65.415 1.00 23.55 ? 373 ASP A CB 1 ATOM 2637 C CG . ASP A 1 353 ? -31.548 -14.812 65.629 1.00 25.76 ? 373 ASP A CG 1 ATOM 2638 O OD1 . ASP A 1 353 ? -31.070 -15.355 66.659 1.00 27.96 ? 373 ASP A OD1 1 ATOM 2639 O OD2 . ASP A 1 353 ? -30.837 -14.290 64.765 1.00 31.58 ? 373 ASP A OD2 1 ATOM 2640 N N . VAL A 1 354 ? -36.123 -16.197 65.723 1.00 22.22 ? 374 VAL A N 1 ATOM 2641 C CA . VAL A 1 354 ? -37.565 -16.006 65.881 1.00 22.49 ? 374 VAL A CA 1 ATOM 2642 C C . VAL A 1 354 ? -37.966 -16.307 67.337 1.00 23.01 ? 374 VAL A C 1 ATOM 2643 O O . VAL A 1 354 ? -38.963 -15.781 67.835 1.00 22.93 ? 374 VAL A O 1 ATOM 2644 C CB . VAL A 1 354 ? -38.390 -16.840 64.856 1.00 22.55 ? 374 VAL A CB 1 ATOM 2645 C CG1 . VAL A 1 354 ? -39.847 -16.878 65.224 1.00 21.94 ? 374 VAL A CG1 1 ATOM 2646 C CG2 . VAL A 1 354 ? -38.219 -16.267 63.440 1.00 21.46 ? 374 VAL A CG2 1 ATOM 2647 N N . GLY A 1 355 ? -37.150 -17.111 68.020 1.00 23.31 ? 375 GLY A N 1 ATOM 2648 C CA . GLY A 1 355 ? -37.311 -17.360 69.446 1.00 23.98 ? 375 GLY A CA 1 ATOM 2649 C C . GLY A 1 355 ? -37.056 -16.137 70.321 1.00 24.30 ? 375 GLY A C 1 ATOM 2650 O O . GLY A 1 355 ? -37.312 -16.178 71.525 1.00 24.32 ? 375 GLY A O 1 ATOM 2651 N N . TRP A 1 356 ? -36.564 -15.059 69.706 1.00 24.49 ? 376 TRP A N 1 ATOM 2652 C CA . TRP A 1 356 ? -36.232 -13.813 70.391 1.00 24.74 ? 376 TRP A CA 1 ATOM 2653 C C . TRP A 1 356 ? -37.001 -12.620 69.832 1.00 24.65 ? 376 TRP A C 1 ATOM 2654 O O . TRP A 1 356 ? -36.661 -11.477 70.121 1.00 25.61 ? 376 TRP A O 1 ATOM 2655 C CB . TRP A 1 356 ? -34.733 -13.551 70.253 1.00 24.78 ? 376 TRP A CB 1 ATOM 2656 C CG . TRP A 1 356 ? -33.894 -14.649 70.817 1.00 25.59 ? 376 TRP A CG 1 ATOM 2657 C CD1 . TRP A 1 356 ? -33.514 -15.801 70.190 1.00 25.64 ? 376 TRP A CD1 1 ATOM 2658 C CD2 . TRP A 1 356 ? -33.341 -14.710 72.131 1.00 25.75 ? 376 TRP A CD2 1 ATOM 2659 N NE1 . TRP A 1 356 ? -32.750 -16.571 71.029 1.00 25.62 ? 376 TRP A NE1 1 ATOM 2660 C CE2 . TRP A 1 356 ? -32.630 -15.925 72.230 1.00 25.25 ? 376 TRP A CE2 1 ATOM 2661 C CE3 . TRP A 1 356 ? -33.362 -13.848 73.231 1.00 25.67 ? 376 TRP A CE3 1 ATOM 2662 C CZ2 . TRP A 1 356 ? -31.953 -16.301 73.387 1.00 26.02 ? 376 TRP A CZ2 1 ATOM 2663 C CZ3 . TRP A 1 356 ? -32.703 -14.232 74.389 1.00 25.95 ? 376 TRP A CZ3 1 ATOM 2664 C CH2 . TRP A 1 356 ? -31.995 -15.439 74.453 1.00 26.37 ? 376 TRP A CH2 1 ATOM 2665 N N . GLY A 1 357 ? -38.037 -12.876 69.041 1.00 24.49 ? 377 GLY A N 1 ATOM 2666 C CA . GLY A 1 357 ? -38.820 -11.814 68.442 1.00 24.22 ? 377 GLY A CA 1 ATOM 2667 C C . GLY A 1 357 ? -37.985 -11.069 67.424 1.00 24.21 ? 377 GLY A C 1 ATOM 2668 O O . GLY A 1 357 ? -37.770 -9.866 67.538 1.00 24.55 ? 377 GLY A O 1 ATOM 2669 N N . LEU A 1 358 ? -37.513 -11.805 66.426 1.00 24.06 ? 378 LEU A N 1 ATOM 2670 C CA . LEU A 1 358 ? -36.708 -11.253 65.330 1.00 23.94 ? 378 LEU A CA 1 ATOM 2671 C C . LEU A 1 358 ? -37.324 -9.982 64.720 1.00 23.37 ? 378 LEU A C 1 ATOM 2672 O O . LEU A 1 358 ? -36.610 -9.035 64.397 1.00 22.87 ? 378 LEU A O 1 ATOM 2673 C CB . LEU A 1 358 ? -36.527 -12.339 64.260 1.00 24.02 ? 378 LEU A CB 1 ATOM 2674 C CG . LEU A 1 358 ? -35.585 -12.144 63.078 1.00 24.63 ? 378 LEU A CG 1 ATOM 2675 C CD1 . LEU A 1 358 ? -34.140 -11.958 63.541 1.00 27.53 ? 378 LEU A CD1 1 ATOM 2676 C CD2 . LEU A 1 358 ? -35.710 -13.366 62.173 1.00 24.40 ? 378 LEU A CD2 1 ATOM 2677 N N . GLY A 1 359 ? -38.651 -9.961 64.602 1.00 22.99 ? 379 GLY A N 1 ATOM 2678 C CA . GLY A 1 359 ? -39.364 -8.829 64.008 1.00 22.80 ? 379 GLY A CA 1 ATOM 2679 C C . GLY A 1 359 ? -39.646 -7.644 64.922 1.00 22.83 ? 379 GLY A C 1 ATOM 2680 O O . GLY A 1 359 ? -40.192 -6.645 64.471 1.00 23.47 ? 379 GLY A O 1 ATOM 2681 N N . SER A 1 360 ? -39.281 -7.735 66.197 1.00 22.54 ? 380 SER A N 1 ATOM 2682 C CA . SER A 1 360 ? -39.570 -6.666 67.154 1.00 22.44 ? 380 SER A CA 1 ATOM 2683 C C . SER A 1 360 ? -38.305 -6.053 67.775 1.00 21.68 ? 380 SER A C 1 ATOM 2684 O O . SER A 1 360 ? -38.383 -5.331 68.763 1.00 21.56 ? 380 SER A O 1 ATOM 2685 C CB . SER A 1 360 ? -40.518 -7.175 68.244 1.00 22.67 ? 380 SER A CB 1 ATOM 2686 O OG . SER A 1 360 ? -39.990 -8.332 68.868 1.00 24.38 ? 380 SER A OG 1 ATOM 2687 N N . VAL A 1 361 ? -37.150 -6.339 67.180 1.00 20.71 ? 381 VAL A N 1 ATOM 2688 C CA . VAL A 1 361 ? -35.899 -5.717 67.572 1.00 20.13 ? 381 VAL A CA 1 ATOM 2689 C C . VAL A 1 361 ? -35.419 -4.835 66.419 1.00 19.72 ? 381 VAL A C 1 ATOM 2690 O O . VAL A 1 361 ? -34.228 -4.731 66.122 1.00 19.34 ? 381 VAL A O 1 ATOM 2691 C CB . VAL A 1 361 ? -34.859 -6.765 68.007 1.00 20.25 ? 381 VAL A CB 1 ATOM 2692 C CG1 . VAL A 1 361 ? -35.226 -7.301 69.376 1.00 19.95 ? 381 VAL A CG1 1 ATOM 2693 C CG2 . VAL A 1 361 ? -34.755 -7.898 66.988 1.00 20.18 ? 381 VAL A CG2 1 ATOM 2694 N N . THR A 1 362 ? -36.406 -4.196 65.798 1.00 19.32 ? 382 THR A N 1 ATOM 2695 C CA . THR A 1 362 ? -36.250 -3.277 64.701 1.00 19.18 ? 382 THR A CA 1 ATOM 2696 C C . THR A 1 362 ? -35.925 -1.876 65.220 1.00 19.37 ? 382 THR A C 1 ATOM 2697 O O . THR A 1 362 ? -36.774 -0.967 65.201 1.00 19.44 ? 382 THR A O 1 ATOM 2698 C CB . THR A 1 362 ? -37.576 -3.215 63.916 1.00 19.35 ? 382 THR A CB 1 ATOM 2699 O OG1 . THR A 1 362 ? -38.638 -2.858 64.812 1.00 17.74 ? 382 THR A OG1 1 ATOM 2700 C CG2 . THR A 1 362 ? -37.889 -4.583 63.278 1.00 19.23 ? 382 THR A CG2 1 ATOM 2701 N N . HIS A 1 363 ? -34.689 -1.689 65.665 1.00 19.52 ? 383 HIS A N 1 ATOM 2702 C CA . HIS A 1 363 ? -34.328 -0.447 66.347 1.00 19.89 ? 383 HIS A CA 1 ATOM 2703 C C . HIS A 1 363 ? -33.984 0.666 65.368 1.00 19.90 ? 383 HIS A C 1 ATOM 2704 O O . HIS A 1 363 ? -33.913 0.449 64.154 1.00 19.61 ? 383 HIS A O 1 ATOM 2705 C CB . HIS A 1 363 ? -33.272 -0.705 67.433 1.00 20.11 ? 383 HIS A CB 1 ATOM 2706 C CG . HIS A 1 363 ? -33.861 -1.336 68.662 1.00 21.54 ? 383 HIS A CG 1 ATOM 2707 N ND1 . HIS A 1 363 ? -34.728 -0.662 69.496 1.00 22.01 ? 383 HIS A ND1 1 ATOM 2708 C CD2 . HIS A 1 363 ? -33.772 -2.595 69.154 1.00 23.26 ? 383 HIS A CD2 1 ATOM 2709 C CE1 . HIS A 1 363 ? -35.119 -1.469 70.467 1.00 22.62 ? 383 HIS A CE1 1 ATOM 2710 N NE2 . HIS A 1 363 ? -34.550 -2.647 70.285 1.00 22.88 ? 383 HIS A NE2 1 ATOM 2711 N N . GLU A 1 364 ? -33.836 1.872 65.899 1.00 20.21 ? 384 GLU A N 1 ATOM 2712 C CA . GLU A 1 364 ? -33.921 3.077 65.101 1.00 20.16 ? 384 GLU A CA 1 ATOM 2713 C C . GLU A 1 364 ? -32.841 3.167 64.023 1.00 20.36 ? 384 GLU A C 1 ATOM 2714 O O . GLU A 1 364 ? -31.645 3.089 64.311 1.00 19.41 ? 384 GLU A O 1 ATOM 2715 C CB . GLU A 1 364 ? -33.881 4.293 66.019 1.00 20.36 ? 384 GLU A CB 1 ATOM 2716 C CG . GLU A 1 364 ? -34.016 5.654 65.324 1.00 21.24 ? 384 GLU A CG 1 ATOM 2717 C CD . GLU A 1 364 ? -34.092 6.796 66.328 1.00 22.95 ? 384 GLU A CD 1 ATOM 2718 O OE1 . GLU A 1 364 ? -34.196 6.523 67.558 1.00 22.33 ? 384 GLU A OE1 1 ATOM 2719 O OE2 . GLU A 1 364 ? -34.050 7.962 65.889 1.00 22.93 ? 384 GLU A OE2 1 ATOM 2720 N N . LEU A 1 365 ? -33.298 3.339 62.781 1.00 20.45 ? 385 LEU A N 1 ATOM 2721 C CA . LEU A 1 365 ? -32.431 3.495 61.632 1.00 20.85 ? 385 LEU A CA 1 ATOM 2722 C C . LEU A 1 365 ? -31.871 4.915 61.603 1.00 21.20 ? 385 LEU A C 1 ATOM 2723 O O . LEU A 1 365 ? -32.635 5.882 61.649 1.00 21.38 ? 385 LEU A O 1 ATOM 2724 C CB . LEU A 1 365 ? -33.214 3.209 60.338 1.00 21.28 ? 385 LEU A CB 1 ATOM 2725 C CG . LEU A 1 365 ? -33.767 1.786 60.158 1.00 20.81 ? 385 LEU A CG 1 ATOM 2726 C CD1 . LEU A 1 365 ? -34.825 1.725 59.030 1.00 20.89 ? 385 LEU A CD1 1 ATOM 2727 C CD2 . LEU A 1 365 ? -32.640 0.822 59.892 1.00 20.52 ? 385 LEU A CD2 1 ATOM 2728 N N . ALA A 1 366 ? -30.543 5.030 61.535 1.00 21.37 ? 386 ALA A N 1 ATOM 2729 C CA . ALA A 1 366 ? -29.858 6.323 61.539 1.00 21.45 ? 386 ALA A CA 1 ATOM 2730 C C . ALA A 1 366 ? -29.825 6.943 60.140 1.00 21.78 ? 386 ALA A C 1 ATOM 2731 O O . ALA A 1 366 ? -29.180 6.390 59.241 1.00 21.81 ? 386 ALA A O 1 ATOM 2732 C CB . ALA A 1 366 ? -28.437 6.161 62.074 1.00 21.06 ? 386 ALA A CB 1 ATOM 2733 N N . PRO A 1 367 ? -30.496 8.100 59.947 1.00 22.40 ? 387 PRO A N 1 ATOM 2734 C CA . PRO A 1 367 ? -30.553 8.681 58.602 1.00 22.90 ? 387 PRO A CA 1 ATOM 2735 C C . PRO A 1 367 ? -29.192 9.101 58.069 1.00 23.46 ? 387 PRO A C 1 ATOM 2736 O O . PRO A 1 367 ? -28.428 9.785 58.763 1.00 23.55 ? 387 PRO A O 1 ATOM 2737 C CB . PRO A 1 367 ? -31.464 9.897 58.778 1.00 22.93 ? 387 PRO A CB 1 ATOM 2738 C CG . PRO A 1 367 ? -32.292 9.562 59.980 1.00 22.89 ? 387 PRO A CG 1 ATOM 2739 C CD . PRO A 1 367 ? -31.331 8.866 60.888 1.00 22.41 ? 387 PRO A CD 1 ATOM 2740 N N . GLY A 1 368 ? -28.899 8.676 56.848 1.00 23.69 ? 388 GLY A N 1 ATOM 2741 C CA . GLY A 1 368 ? -27.601 8.916 56.235 1.00 24.20 ? 388 GLY A CA 1 ATOM 2742 C C . GLY A 1 368 ? -26.608 7.795 56.432 1.00 24.43 ? 388 GLY A C 1 ATOM 2743 O O . GLY A 1 368 ? -25.579 7.770 55.753 1.00 25.43 ? 388 GLY A O 1 ATOM 2744 N N . ILE A 1 369 ? -26.901 6.867 57.349 1.00 24.19 ? 389 ILE A N 1 ATOM 2745 C CA . ILE A 1 369 ? -26.005 5.749 57.638 1.00 23.83 ? 389 ILE A CA 1 ATOM 2746 C C . ILE A 1 369 ? -26.710 4.440 57.311 1.00 23.28 ? 389 ILE A C 1 ATOM 2747 O O . ILE A 1 369 ? -26.317 3.750 56.374 1.00 23.69 ? 389 ILE A O 1 ATOM 2748 C CB . ILE A 1 369 ? -25.514 5.765 59.112 1.00 23.85 ? 389 ILE A CB 1 ATOM 2749 C CG1 . ILE A 1 369 ? -24.715 7.039 59.399 1.00 25.04 ? 389 ILE A CG1 1 ATOM 2750 C CG2 . ILE A 1 369 ? -24.624 4.574 59.391 1.00 23.80 ? 389 ILE A CG2 1 ATOM 2751 C CD1 . ILE A 1 369 ? -24.304 7.208 60.863 1.00 24.90 ? 389 ILE A CD1 1 ATOM 2752 N N . ASP A 1 370 ? -27.762 4.119 58.073 1.00 22.64 ? 390 ASP A N 1 ATOM 2753 C CA . ASP A 1 370 ? -28.536 2.881 57.893 1.00 21.55 ? 390 ASP A CA 1 ATOM 2754 C C . ASP A 1 370 ? -29.378 2.904 56.611 1.00 21.19 ? 390 ASP A C 1 ATOM 2755 O O . ASP A 1 370 ? -29.558 1.873 55.962 1.00 19.84 ? 390 ASP A O 1 ATOM 2756 C CB . ASP A 1 370 ? -29.447 2.640 59.099 1.00 21.37 ? 390 ASP A CB 1 ATOM 2757 C CG . ASP A 1 370 ? -28.680 2.277 60.367 1.00 21.43 ? 390 ASP A CG 1 ATOM 2758 O OD1 . ASP A 1 370 ? -27.602 1.647 60.284 1.00 22.27 ? 390 ASP A OD1 1 ATOM 2759 O OD2 . ASP A 1 370 ? -29.165 2.603 61.471 1.00 19.39 ? 390 ASP A OD2 1 ATOM 2760 N N . CYS A 1 371 ? -29.908 4.080 56.269 1.00 20.99 ? 391 CYS A N 1 ATOM 2761 C CA . CYS A 1 371 ? -30.532 4.315 54.967 1.00 21.27 ? 391 CYS A CA 1 ATOM 2762 C C . CYS A 1 371 ? -30.055 5.686 54.491 1.00 21.25 ? 391 CYS A C 1 ATOM 2763 O O . CYS A 1 371 ? -29.556 6.467 55.294 1.00 21.31 ? 391 CYS A O 1 ATOM 2764 C CB . CYS A 1 371 ? -32.074 4.277 55.052 1.00 21.25 ? 391 CYS A CB 1 ATOM 2765 S SG . CYS A 1 371 ? -32.748 2.918 56.056 1.00 21.55 ? 391 CYS A SG 1 ATOM 2766 N N . PRO A 1 372 ? -30.187 5.979 53.185 1.00 21.57 ? 392 PRO A N 1 ATOM 2767 C CA . PRO A 1 372 ? -29.818 7.324 52.717 1.00 21.97 ? 392 PRO A CA 1 ATOM 2768 C C . PRO A 1 372 ? -30.605 8.425 53.416 1.00 22.35 ? 392 PRO A C 1 ATOM 2769 O O . PRO A 1 372 ? -31.736 8.192 53.860 1.00 22.33 ? 392 PRO A O 1 ATOM 2770 C CB . PRO A 1 372 ? -30.167 7.312 51.222 1.00 21.89 ? 392 PRO A CB 1 ATOM 2771 C CG . PRO A 1 372 ? -30.322 5.894 50.838 1.00 22.12 ? 392 PRO A CG 1 ATOM 2772 C CD . PRO A 1 372 ? -30.563 5.076 52.084 1.00 21.60 ? 392 PRO A CD 1 ATOM 2773 N N . GLU A 1 373 ? -30.008 9.619 53.488 1.00 22.74 ? 393 GLU A N 1 ATOM 2774 C CA . GLU A 1 373 ? -30.659 10.784 54.087 1.00 23.00 ? 393 GLU A CA 1 ATOM 2775 C C . GLU A 1 373 ? -31.967 11.091 53.385 1.00 22.07 ? 393 GLU A C 1 ATOM 2776 O O . GLU A 1 373 ? -32.832 11.726 53.953 1.00 22.15 ? 393 GLU A O 1 ATOM 2777 C CB . GLU A 1 373 ? -29.784 12.036 53.994 1.00 23.51 ? 393 GLU A CB 1 ATOM 2778 C CG . GLU A 1 373 ? -28.487 11.971 54.732 1.00 26.10 ? 393 GLU A CG 1 ATOM 2779 C CD . GLU A 1 373 ? -27.356 11.514 53.861 1.00 29.13 ? 393 GLU A CD 1 ATOM 2780 O OE1 . GLU A 1 373 ? -27.535 10.565 53.059 1.00 30.96 ? 393 GLU A OE1 1 ATOM 2781 O OE2 . GLU A 1 373 ? -26.274 12.112 53.981 1.00 33.90 ? 393 GLU A OE2 1 ATOM 2782 N N . THR A 1 374 ? -32.077 10.654 52.139 1.00 21.48 ? 394 THR A N 1 ATOM 2783 C CA . THR A 1 374 ? -33.259 10.866 51.318 1.00 20.93 ? 394 THR A CA 1 ATOM 2784 C C . THR A 1 374 ? -34.372 9.809 51.500 1.00 20.58 ? 394 THR A C 1 ATOM 2785 O O . THR A 1 374 ? -35.423 9.897 50.855 1.00 19.85 ? 394 THR A O 1 ATOM 2786 C CB . THR A 1 374 ? -32.829 10.888 49.851 1.00 21.25 ? 394 THR A CB 1 ATOM 2787 O OG1 . THR A 1 374 ? -32.093 9.697 49.563 1.00 21.23 ? 394 THR A OG1 1 ATOM 2788 C CG2 . THR A 1 374 ? -31.916 12.122 49.558 1.00 20.81 ? 394 THR A CG2 1 ATOM 2789 N N . ALA A 1 375 ? -34.158 8.823 52.372 1.00 19.96 ? 395 ALA A N 1 ATOM 2790 C CA . ALA A 1 375 ? -35.153 7.754 52.564 1.00 19.59 ? 395 ALA A CA 1 ATOM 2791 C C . ALA A 1 375 ? -36.407 8.226 53.288 1.00 19.27 ? 395 ALA A C 1 ATOM 2792 O O . ALA A 1 375 ? -36.373 9.187 54.055 1.00 18.11 ? 395 ALA A O 1 ATOM 2793 C CB . ALA A 1 375 ? -34.547 6.583 53.332 1.00 19.01 ? 395 ALA A CB 1 ATOM 2794 N N . THR A 1 376 ? -37.509 7.515 53.042 1.00 19.18 ? 396 THR A N 1 ATOM 2795 C CA . THR A 1 376 ? -38.699 7.644 53.854 1.00 18.68 ? 396 THR A CA 1 ATOM 2796 C C . THR A 1 376 ? -38.527 6.676 55.011 1.00 19.55 ? 396 THR A C 1 ATOM 2797 O O . THR A 1 376 ? -38.322 5.470 54.799 1.00 19.92 ? 396 THR A O 1 ATOM 2798 C CB . THR A 1 376 ? -39.972 7.289 53.077 1.00 18.94 ? 396 THR A CB 1 ATOM 2799 O OG1 . THR A 1 376 ? -40.014 8.047 51.863 1.00 17.42 ? 396 THR A OG1 1 ATOM 2800 C CG2 . THR A 1 376 ? -41.235 7.566 53.938 1.00 17.26 ? 396 THR A CG2 1 ATOM 2801 N N . PHE A 1 377 ? -38.591 7.214 56.226 1.00 19.47 ? 397 PHE A N 1 ATOM 2802 C CA . PHE A 1 377 ? -38.418 6.446 57.447 1.00 19.48 ? 397 PHE A CA 1 ATOM 2803 C C . PHE A 1 377 ? -39.781 6.266 58.092 1.00 19.51 ? 397 PHE A C 1 ATOM 2804 O O . PHE A 1 377 ? -40.580 7.195 58.119 1.00 19.90 ? 397 PHE A O 1 ATOM 2805 C CB . PHE A 1 377 ? -37.473 7.170 58.404 1.00 19.38 ? 397 PHE A CB 1 ATOM 2806 C CG . PHE A 1 377 ? -36.052 7.249 57.911 1.00 19.81 ? 397 PHE A CG 1 ATOM 2807 C CD1 . PHE A 1 377 ? -35.633 8.313 57.139 1.00 19.55 ? 397 PHE A CD1 1 ATOM 2808 C CD2 . PHE A 1 377 ? -35.134 6.254 58.227 1.00 20.32 ? 397 PHE A CD2 1 ATOM 2809 C CE1 . PHE A 1 377 ? -34.335 8.392 56.685 1.00 20.08 ? 397 PHE A CE1 1 ATOM 2810 C CE2 . PHE A 1 377 ? -33.821 6.326 57.775 1.00 20.45 ? 397 PHE A CE2 1 ATOM 2811 C CZ . PHE A 1 377 ? -33.423 7.395 56.998 1.00 20.18 ? 397 PHE A CZ 1 ATOM 2812 N N . LEU A 1 378 ? -40.042 5.070 58.602 1.00 19.29 ? 398 LEU A N 1 ATOM 2813 C CA . LEU A 1 378 ? -41.352 4.711 59.096 1.00 19.86 ? 398 LEU A CA 1 ATOM 2814 C C . LEU A 1 378 ? -41.273 4.172 60.509 1.00 20.11 ? 398 LEU A C 1 ATOM 2815 O O . LEU A 1 378 ? -40.404 3.366 60.829 1.00 20.03 ? 398 LEU A O 1 ATOM 2816 C CB . LEU A 1 378 ? -41.971 3.647 58.201 1.00 19.77 ? 398 LEU A CB 1 ATOM 2817 C CG . LEU A 1 378 ? -42.290 4.080 56.777 1.00 20.32 ? 398 LEU A CG 1 ATOM 2818 C CD1 . LEU A 1 378 ? -42.762 2.883 55.992 1.00 19.16 ? 398 LEU A CD1 1 ATOM 2819 C CD2 . LEU A 1 378 ? -43.339 5.206 56.772 1.00 19.48 ? 398 LEU A CD2 1 ATOM 2820 N N . ASP A 1 379 ? -42.199 4.623 61.343 1.00 20.82 ? 399 ASP A N 1 ATOM 2821 C CA . ASP A 1 379 ? -42.348 4.110 62.700 1.00 21.47 ? 399 ASP A CA 1 ATOM 2822 C C . ASP A 1 379 ? -43.173 2.843 62.716 1.00 21.32 ? 399 ASP A C 1 ATOM 2823 O O . ASP A 1 379 ? -43.929 2.568 61.780 1.00 21.23 ? 399 ASP A O 1 ATOM 2824 C CB . ASP A 1 379 ? -43.051 5.141 63.578 1.00 21.68 ? 399 ASP A CB 1 ATOM 2825 C CG . ASP A 1 379 ? -42.243 6.394 63.755 1.00 23.30 ? 399 ASP A CG 1 ATOM 2826 O OD1 . ASP A 1 379 ? -41.118 6.483 63.212 1.00 24.18 ? 399 ASP A OD1 1 ATOM 2827 O OD2 . ASP A 1 379 ? -42.736 7.290 64.448 1.00 27.42 ? 399 ASP A OD2 1 ATOM 2828 N N . THR A 1 380 ? -43.032 2.071 63.790 1.00 21.30 ? 400 THR A N 1 ATOM 2829 C CA . THR A 1 380 ? -44.000 1.033 64.071 1.00 21.54 ? 400 THR A CA 1 ATOM 2830 C C . THR A 1 380 ? -44.243 0.880 65.563 1.00 21.36 ? 400 THR A C 1 ATOM 2831 O O . THR A 1 380 ? -43.641 1.571 66.379 1.00 21.22 ? 400 THR A O 1 ATOM 2832 C CB . THR A 1 380 ? -43.619 -0.326 63.412 1.00 21.76 ? 400 THR A CB 1 ATOM 2833 O OG1 . THR A 1 380 ? -44.808 -1.109 63.240 1.00 21.13 ? 400 THR A OG1 1 ATOM 2834 C CG2 . THR A 1 380 ? -42.608 -1.109 64.252 1.00 21.28 ? 400 THR A CG2 1 ATOM 2835 N N . PHE A 1 381 ? -45.177 0.000 65.892 1.00 21.65 ? 401 PHE A N 1 ATOM 2836 C CA . PHE A 1 381 ? -45.465 -0.375 67.263 1.00 22.04 ? 401 PHE A CA 1 ATOM 2837 C C . PHE A 1 381 ? -45.304 -1.883 67.409 1.00 22.42 ? 401 PHE A C 1 ATOM 2838 O O . PHE A 1 381 ? -45.705 -2.642 66.521 1.00 22.24 ? 401 PHE A O 1 ATOM 2839 C CB . PHE A 1 381 ? -46.889 0.037 67.636 1.00 22.20 ? 401 PHE A CB 1 ATOM 2840 C CG . PHE A 1 381 ? -47.015 1.475 68.096 1.00 22.46 ? 401 PHE A CG 1 ATOM 2841 C CD1 . PHE A 1 381 ? -47.225 2.496 67.183 1.00 22.63 ? 401 PHE A CD1 1 ATOM 2842 C CD2 . PHE A 1 381 ? -46.939 1.791 69.448 1.00 22.85 ? 401 PHE A CD2 1 ATOM 2843 C CE1 . PHE A 1 381 ? -47.358 3.816 67.609 1.00 24.00 ? 401 PHE A CE1 1 ATOM 2844 C CE2 . PHE A 1 381 ? -47.072 3.107 69.887 1.00 23.22 ? 401 PHE A CE2 1 ATOM 2845 C CZ . PHE A 1 381 ? -47.281 4.119 68.967 1.00 23.28 ? 401 PHE A CZ 1 ATOM 2846 N N . HIS A 1 382 ? -44.693 -2.303 68.516 1.00 22.66 ? 402 HIS A N 1 ATOM 2847 C CA . HIS A 1 382 ? -44.592 -3.718 68.877 1.00 22.95 ? 402 HIS A CA 1 ATOM 2848 C C . HIS A 1 382 ? -45.159 -3.959 70.268 1.00 22.86 ? 402 HIS A C 1 ATOM 2849 O O . HIS A 1 382 ? -44.989 -3.142 71.158 1.00 22.49 ? 402 HIS A O 1 ATOM 2850 C CB . HIS A 1 382 ? -43.127 -4.174 68.891 1.00 22.85 ? 402 HIS A CB 1 ATOM 2851 C CG . HIS A 1 382 ? -42.488 -4.208 67.541 1.00 24.35 ? 402 HIS A CG 1 ATOM 2852 N ND1 . HIS A 1 382 ? -42.989 -4.960 66.499 1.00 23.95 ? 402 HIS A ND1 1 ATOM 2853 C CD2 . HIS A 1 382 ? -41.382 -3.589 67.064 1.00 25.19 ? 402 HIS A CD2 1 ATOM 2854 C CE1 . HIS A 1 382 ? -42.227 -4.789 65.434 1.00 25.13 ? 402 HIS A CE1 1 ATOM 2855 N NE2 . HIS A 1 382 ? -41.238 -3.970 65.753 1.00 25.03 ? 402 HIS A NE2 1 ATOM 2856 N N . TYR A 1 383 ? -45.818 -5.096 70.448 1.00 23.55 ? 403 TYR A N 1 ATOM 2857 C CA . TYR A 1 383 ? -46.154 -5.592 71.772 1.00 23.89 ? 403 TYR A CA 1 ATOM 2858 C C . TYR A 1 383 ? -45.523 -6.971 71.923 1.00 24.01 ? 403 TYR A C 1 ATOM 2859 O O . TYR A 1 383 ? -46.074 -7.964 71.464 1.00 23.32 ? 403 TYR A O 1 ATOM 2860 C CB . TYR A 1 383 ? -47.665 -5.651 71.958 1.00 24.23 ? 403 TYR A CB 1 ATOM 2861 C CG . TYR A 1 383 ? -48.082 -6.008 73.365 1.00 25.98 ? 403 TYR A CG 1 ATOM 2862 C CD1 . TYR A 1 383 ? -48.437 -5.025 74.283 1.00 28.43 ? 403 TYR A CD1 1 ATOM 2863 C CD2 . TYR A 1 383 ? -48.140 -7.330 73.769 1.00 27.98 ? 403 TYR A CD2 1 ATOM 2864 C CE1 . TYR A 1 383 ? -48.830 -5.365 75.582 1.00 30.09 ? 403 TYR A CE1 1 ATOM 2865 C CE2 . TYR A 1 383 ? -48.521 -7.676 75.044 1.00 30.11 ? 403 TYR A CE2 1 ATOM 2866 C CZ . TYR A 1 383 ? -48.867 -6.698 75.948 1.00 29.97 ? 403 TYR A CZ 1 ATOM 2867 O OH . TYR A 1 383 ? -49.247 -7.082 77.208 1.00 32.38 ? 403 TYR A OH 1 ATOM 2868 N N . TYR A 1 384 ? -44.339 -6.996 72.532 1.00 24.56 ? 404 TYR A N 1 ATOM 2869 C CA . TYR A 1 384 ? -43.562 -8.212 72.741 1.00 25.15 ? 404 TYR A CA 1 ATOM 2870 C C . TYR A 1 384 ? -42.856 -8.077 74.096 1.00 25.30 ? 404 TYR A C 1 ATOM 2871 O O . TYR A 1 384 ? -41.976 -7.235 74.243 1.00 24.83 ? 404 TYR A O 1 ATOM 2872 C CB . TYR A 1 384 ? -42.534 -8.401 71.608 1.00 25.47 ? 404 TYR A CB 1 ATOM 2873 C CG . TYR A 1 384 ? -41.662 -9.634 71.776 1.00 27.10 ? 404 TYR A CG 1 ATOM 2874 C CD1 . TYR A 1 384 ? -41.886 -10.786 71.025 1.00 28.37 ? 404 TYR A CD1 1 ATOM 2875 C CD2 . TYR A 1 384 ? -40.626 -9.656 72.712 1.00 28.75 ? 404 TYR A CD2 1 ATOM 2876 C CE1 . TYR A 1 384 ? -41.090 -11.929 71.202 1.00 29.20 ? 404 TYR A CE1 1 ATOM 2877 C CE2 . TYR A 1 384 ? -39.833 -10.787 72.899 1.00 28.98 ? 404 TYR A CE2 1 ATOM 2878 C CZ . TYR A 1 384 ? -40.059 -11.917 72.142 1.00 30.24 ? 404 TYR A CZ 1 ATOM 2879 O OH . TYR A 1 384 ? -39.254 -13.032 72.341 1.00 30.86 ? 404 TYR A OH 1 ATOM 2880 N N . ASP A 1 385 ? -43.240 -8.899 75.075 1.00 25.33 ? 405 ASP A N 1 ATOM 2881 C CA . ASP A 1 385 ? -42.693 -8.810 76.442 1.00 25.69 ? 405 ASP A CA 1 ATOM 2882 C C . ASP A 1 385 ? -42.789 -7.382 77.017 1.00 26.04 ? 405 ASP A C 1 ATOM 2883 O O . ASP A 1 385 ? -41.807 -6.815 77.474 1.00 26.47 ? 405 ASP A O 1 ATOM 2884 C CB . ASP A 1 385 ? -41.240 -9.291 76.478 1.00 25.88 ? 405 ASP A CB 1 ATOM 2885 C CG . ASP A 1 385 ? -40.713 -9.473 77.895 1.00 25.60 ? 405 ASP A CG 1 ATOM 2886 O OD1 . ASP A 1 385 ? -41.538 -9.630 78.819 1.00 26.06 ? 405 ASP A OD1 1 ATOM 2887 O OD2 . ASP A 1 385 ? -39.476 -9.475 78.080 1.00 24.77 ? 405 ASP A OD2 1 ATOM 2888 N N . ALA A 1 386 ? -43.979 -6.808 76.980 1.00 26.13 ? 406 ALA A N 1 ATOM 2889 C CA . ALA A 1 386 ? -44.159 -5.413 77.367 1.00 26.64 ? 406 ALA A CA 1 ATOM 2890 C C . ALA A 1 386 ? -45.468 -5.243 78.121 1.00 26.71 ? 406 ALA A C 1 ATOM 2891 O O . ALA A 1 386 ? -46.367 -6.069 78.009 1.00 26.59 ? 406 ALA A O 1 ATOM 2892 C CB . ALA A 1 386 ? -44.141 -4.511 76.120 1.00 26.61 ? 406 ALA A CB 1 ATOM 2893 N N . ASP A 1 387 ? -45.564 -4.164 78.886 1.00 27.26 ? 407 ASP A N 1 ATOM 2894 C CA . ASP A 1 387 ? -46.789 -3.833 79.625 1.00 27.57 ? 407 ASP A CA 1 ATOM 2895 C C . ASP A 1 387 ? -47.782 -3.071 78.761 1.00 27.25 ? 407 ASP A C 1 ATOM 2896 O O . ASP A 1 387 ? -48.990 -3.134 78.998 1.00 27.40 ? 407 ASP A O 1 ATOM 2897 C CB . ASP A 1 387 ? -46.450 -2.998 80.858 1.00 27.97 ? 407 ASP A CB 1 ATOM 2898 C CG . ASP A 1 387 ? -45.604 -3.753 81.858 1.00 29.50 ? 407 ASP A CG 1 ATOM 2899 O OD1 . ASP A 1 387 ? -45.651 -5.002 81.855 1.00 30.22 ? 407 ASP A OD1 1 ATOM 2900 O OD2 . ASP A 1 387 ? -44.899 -3.096 82.659 1.00 32.00 ? 407 ASP A OD2 1 ATOM 2901 N N . ASP A 1 388 ? -47.262 -2.320 77.788 1.00 26.69 ? 408 ASP A N 1 ATOM 2902 C CA . ASP A 1 388 ? -48.077 -1.558 76.848 1.00 26.18 ? 408 ASP A CA 1 ATOM 2903 C C . ASP A 1 388 ? -47.425 -1.622 75.473 1.00 25.42 ? 408 ASP A C 1 ATOM 2904 O O . ASP A 1 388 ? -46.229 -1.898 75.384 1.00 24.82 ? 408 ASP A O 1 ATOM 2905 C CB . ASP A 1 388 ? -48.141 -0.088 77.274 1.00 26.25 ? 408 ASP A CB 1 ATOM 2906 C CG . ASP A 1 388 ? -48.730 0.095 78.651 1.00 27.25 ? 408 ASP A CG 1 ATOM 2907 O OD1 . ASP A 1 388 ? -49.973 0.086 78.768 1.00 28.16 ? 408 ASP A OD1 1 ATOM 2908 O OD2 . ASP A 1 388 ? -47.947 0.237 79.611 1.00 28.63 ? 408 ASP A OD2 1 ATOM 2909 N N . PRO A 1 389 ? -48.194 -1.336 74.407 1.00 24.56 ? 409 PRO A N 1 ATOM 2910 C CA . PRO A 1 389 ? -47.578 -1.218 73.091 1.00 24.46 ? 409 PRO A CA 1 ATOM 2911 C C . PRO A 1 389 ? -46.468 -0.159 73.099 1.00 24.40 ? 409 PRO A C 1 ATOM 2912 O O . PRO A 1 389 ? -46.593 0.864 73.791 1.00 24.41 ? 409 PRO A O 1 ATOM 2913 C CB . PRO A 1 389 ? -48.736 -0.789 72.193 1.00 24.52 ? 409 PRO A CB 1 ATOM 2914 C CG . PRO A 1 389 ? -49.983 -1.139 72.956 1.00 24.44 ? 409 PRO A CG 1 ATOM 2915 C CD . PRO A 1 389 ? -49.628 -0.994 74.378 1.00 24.44 ? 409 PRO A CD 1 ATOM 2916 N N . VAL A 1 390 ? -45.387 -0.434 72.375 1.00 23.68 ? 410 VAL A N 1 ATOM 2917 C CA . VAL A 1 390 ? -44.182 0.390 72.406 1.00 23.58 ? 410 VAL A CA 1 ATOM 2918 C C . VAL A 1 390 ? -43.895 0.959 71.024 1.00 23.37 ? 410 VAL A C 1 ATOM 2919 O O . VAL A 1 390 ? -43.908 0.223 70.035 1.00 23.18 ? 410 VAL A O 1 ATOM 2920 C CB . VAL A 1 390 ? -42.966 -0.436 72.848 1.00 23.69 ? 410 VAL A CB 1 ATOM 2921 C CG1 . VAL A 1 390 ? -41.688 0.426 72.844 1.00 23.01 ? 410 VAL A CG1 1 ATOM 2922 C CG2 . VAL A 1 390 ? -43.217 -1.058 74.225 1.00 23.04 ? 410 VAL A CG2 1 ATOM 2923 N N . HIS A 1 391 ? -43.640 2.265 70.970 1.00 22.96 ? 411 HIS A N 1 ATOM 2924 C CA . HIS A 1 391 ? -43.332 2.966 69.727 1.00 22.80 ? 411 HIS A CA 1 ATOM 2925 C C . HIS A 1 391 ? -41.862 2.772 69.361 1.00 22.31 ? 411 HIS A C 1 ATOM 2926 O O . HIS A 1 391 ? -40.974 3.005 70.181 1.00 22.22 ? 411 HIS A O 1 ATOM 2927 C CB . HIS A 1 391 ? -43.643 4.458 69.876 1.00 22.97 ? 411 HIS A CB 1 ATOM 2928 C CG . HIS A 1 391 ? -43.307 5.287 68.671 1.00 23.26 ? 411 HIS A CG 1 ATOM 2929 N ND1 . HIS A 1 391 ? -42.157 6.044 68.587 1.00 24.76 ? 411 HIS A ND1 1 ATOM 2930 C CD2 . HIS A 1 391 ? -43.981 5.498 67.515 1.00 23.15 ? 411 HIS A CD2 1 ATOM 2931 C CE1 . HIS A 1 391 ? -42.136 6.680 67.428 1.00 24.64 ? 411 HIS A CE1 1 ATOM 2932 N NE2 . HIS A 1 391 ? -43.233 6.369 66.760 1.00 23.65 ? 411 HIS A NE2 1 ATOM 2933 N N . TYR A 1 392 ? -41.627 2.330 68.129 1.00 21.98 ? 412 TYR A N 1 ATOM 2934 C CA . TYR A 1 392 ? -40.286 2.092 67.602 1.00 21.79 ? 412 TYR A CA 1 ATOM 2935 C C . TYR A 1 392 ? -40.061 3.092 66.476 1.00 21.44 ? 412 TYR A C 1 ATOM 2936 O O . TYR A 1 392 ? -40.598 2.923 65.386 1.00 21.22 ? 412 TYR A O 1 ATOM 2937 C CB . TYR A 1 392 ? -40.155 0.648 67.083 1.00 21.84 ? 412 TYR A CB 1 ATOM 2938 C CG . TYR A 1 392 ? -39.879 -0.365 68.171 1.00 22.39 ? 412 TYR A CG 1 ATOM 2939 C CD1 . TYR A 1 392 ? -40.869 -0.707 69.094 1.00 23.55 ? 412 TYR A CD1 1 ATOM 2940 C CD2 . TYR A 1 392 ? -38.629 -0.971 68.292 1.00 23.88 ? 412 TYR A CD2 1 ATOM 2941 C CE1 . TYR A 1 392 ? -40.627 -1.628 70.097 1.00 22.61 ? 412 TYR A CE1 1 ATOM 2942 C CE2 . TYR A 1 392 ? -38.371 -1.888 69.294 1.00 23.80 ? 412 TYR A CE2 1 ATOM 2943 C CZ . TYR A 1 392 ? -39.380 -2.211 70.197 1.00 23.61 ? 412 TYR A CZ 1 ATOM 2944 O OH . TYR A 1 392 ? -39.136 -3.122 71.192 1.00 24.51 ? 412 TYR A OH 1 ATOM 2945 N N . PRO A 1 393 ? -39.283 4.150 66.739 1.00 21.24 ? 413 PRO A N 1 ATOM 2946 C CA . PRO A 1 393 ? -39.052 5.160 65.708 1.00 21.17 ? 413 PRO A CA 1 ATOM 2947 C C . PRO A 1 393 ? -38.154 4.643 64.586 1.00 20.61 ? 413 PRO A C 1 ATOM 2948 O O . PRO A 1 393 ? -37.163 3.977 64.854 1.00 20.35 ? 413 PRO A O 1 ATOM 2949 C CB . PRO A 1 393 ? -38.343 6.296 66.462 1.00 20.88 ? 413 PRO A CB 1 ATOM 2950 C CG . PRO A 1 393 ? -38.213 5.871 67.842 1.00 21.69 ? 413 PRO A CG 1 ATOM 2951 C CD . PRO A 1 393 ? -38.509 4.428 67.954 1.00 21.17 ? 413 PRO A CD 1 ATOM 2952 N N . ARG A 1 394 ? -38.510 4.959 63.349 1.00 20.46 ? 414 ARG A N 1 ATOM 2953 C CA . ARG A 1 394 ? -37.693 4.614 62.189 1.00 20.50 ? 414 ARG A CA 1 ATOM 2954 C C . ARG A 1 394 ? -37.288 3.153 62.215 1.00 19.98 ? 414 ARG A C 1 ATOM 2955 O O . ARG A 1 394 ? -36.108 2.823 62.093 1.00 19.32 ? 414 ARG A O 1 ATOM 2956 C CB . ARG A 1 394 ? -36.446 5.483 62.137 1.00 20.57 ? 414 ARG A CB 1 ATOM 2957 C CG . ARG A 1 394 ? -36.712 6.973 62.154 1.00 21.99 ? 414 ARG A CG 1 ATOM 2958 C CD . ARG A 1 394 ? -35.377 7.644 62.139 1.00 23.94 ? 414 ARG A CD 1 ATOM 2959 N NE . ARG A 1 394 ? -35.423 9.097 62.051 1.00 24.61 ? 414 ARG A NE 1 ATOM 2960 C CZ . ARG A 1 394 ? -34.539 9.904 62.628 1.00 24.69 ? 414 ARG A CZ 1 ATOM 2961 N NH1 . ARG A 1 394 ? -33.562 9.410 63.391 1.00 24.29 ? 414 ARG A NH1 1 ATOM 2962 N NH2 . ARG A 1 394 ? -34.647 11.213 62.472 1.00 25.82 ? 414 ARG A NH2 1 ATOM 2963 N N . ALA A 1 395 ? -38.283 2.297 62.410 1.00 19.70 ? 415 ALA A N 1 ATOM 2964 C CA . ALA A 1 395 ? -38.101 0.858 62.395 1.00 19.93 ? 415 ALA A CA 1 ATOM 2965 C C . ALA A 1 395 ? -37.821 0.341 60.987 1.00 19.92 ? 415 ALA A C 1 ATOM 2966 O O . ALA A 1 395 ? -37.091 -0.631 60.836 1.00 20.44 ? 415 ALA A O 1 ATOM 2967 C CB . ALA A 1 395 ? -39.340 0.170 62.973 1.00 20.19 ? 415 ALA A CB 1 ATOM 2968 N N . LEU A 1 396 ? -38.436 0.969 59.979 1.00 19.86 ? 416 LEU A N 1 ATOM 2969 C CA . LEU A 1 396 ? -38.228 0.625 58.566 1.00 19.92 ? 416 LEU A CA 1 ATOM 2970 C C . LEU A 1 396 ? -37.868 1.862 57.738 1.00 19.79 ? 416 LEU A C 1 ATOM 2971 O O . LEU A 1 396 ? -38.154 2.999 58.128 1.00 19.38 ? 416 LEU A O 1 ATOM 2972 C CB . LEU A 1 396 ? -39.498 0.044 57.933 1.00 20.21 ? 416 LEU A CB 1 ATOM 2973 C CG . LEU A 1 396 ? -40.324 -1.057 58.574 1.00 20.95 ? 416 LEU A CG 1 ATOM 2974 C CD1 . LEU A 1 396 ? -41.373 -0.465 59.534 1.00 19.94 ? 416 LEU A CD1 1 ATOM 2975 C CD2 . LEU A 1 396 ? -41.013 -1.879 57.469 1.00 21.48 ? 416 LEU A CD2 1 ATOM 2976 N N . CYS A 1 397 ? -37.270 1.636 56.574 1.00 19.56 ? 417 CYS A N 1 ATOM 2977 C CA . CYS A 1 397 ? -37.127 2.696 55.592 1.00 19.43 ? 417 CYS A CA 1 ATOM 2978 C C . CYS A 1 397 ? -37.384 2.177 54.184 1.00 19.37 ? 417 CYS A C 1 ATOM 2979 O O . CYS A 1 397 ? -37.208 0.985 53.895 1.00 19.14 ? 417 CYS A O 1 ATOM 2980 C CB . CYS A 1 397 ? -35.746 3.344 55.679 1.00 19.76 ? 417 CYS A CB 1 ATOM 2981 S SG . CYS A 1 397 ? -34.443 2.292 55.098 1.00 20.50 ? 417 CYS A SG 1 ATOM 2982 N N . LEU A 1 398 ? -37.801 3.096 53.316 1.00 19.11 ? 418 LEU A N 1 ATOM 2983 C CA . LEU A 1 398 ? -38.074 2.804 51.924 1.00 18.64 ? 418 LEU A CA 1 ATOM 2984 C C . LEU A 1 398 ? -37.406 3.930 51.153 1.00 18.59 ? 418 LEU A C 1 ATOM 2985 O O . LEU A 1 398 ? -37.580 5.097 51.494 1.00 17.77 ? 418 LEU A O 1 ATOM 2986 C CB . LEU A 1 398 ? -39.589 2.764 51.677 1.00 18.71 ? 418 LEU A CB 1 ATOM 2987 C CG . LEU A 1 398 ? -40.104 2.415 50.286 1.00 18.56 ? 418 LEU A CG 1 ATOM 2988 C CD1 . LEU A 1 398 ? -39.673 1.020 49.926 1.00 17.56 ? 418 LEU A CD1 1 ATOM 2989 C CD2 . LEU A 1 398 ? -41.635 2.543 50.217 1.00 18.69 ? 418 LEU A CD2 1 ATOM 2990 N N . PHE A 1 399 ? -36.614 3.573 50.143 1.00 18.34 ? 419 PHE A N 1 ATOM 2991 C CA . PHE A 1 399 ? -35.855 4.552 49.388 1.00 18.35 ? 419 PHE A CA 1 ATOM 2992 C C . PHE A 1 399 ? -35.450 4.064 48.005 1.00 18.90 ? 419 PHE A C 1 ATOM 2993 O O . PHE A 1 399 ? -35.270 2.861 47.782 1.00 18.83 ? 419 PHE A O 1 ATOM 2994 C CB . PHE A 1 399 ? -34.609 4.974 50.173 1.00 18.41 ? 419 PHE A CB 1 ATOM 2995 C CG . PHE A 1 399 ? -33.619 3.862 50.440 1.00 18.01 ? 419 PHE A CG 1 ATOM 2996 C CD1 . PHE A 1 399 ? -32.540 3.652 49.587 1.00 19.51 ? 419 PHE A CD1 1 ATOM 2997 C CD2 . PHE A 1 399 ? -33.715 3.092 51.574 1.00 18.35 ? 419 PHE A CD2 1 ATOM 2998 C CE1 . PHE A 1 399 ? -31.602 2.661 49.840 1.00 19.11 ? 419 PHE A CE1 1 ATOM 2999 C CE2 . PHE A 1 399 ? -32.787 2.080 51.835 1.00 19.41 ? 419 PHE A CE2 1 ATOM 3000 C CZ . PHE A 1 399 ? -31.724 1.873 50.969 1.00 19.78 ? 419 PHE A CZ 1 ATOM 3001 N N . GLU A 1 400 ? -35.320 5.007 47.077 1.00 19.28 ? 420 GLU A N 1 ATOM 3002 C CA . GLU A 1 400 ? -34.779 4.723 45.764 1.00 19.66 ? 420 GLU A CA 1 ATOM 3003 C C . GLU A 1 400 ? -33.325 5.130 45.784 1.00 20.43 ? 420 GLU A C 1 ATOM 3004 O O . GLU A 1 400 ? -32.981 6.160 46.340 1.00 21.07 ? 420 GLU A O 1 ATOM 3005 C CB . GLU A 1 400 ? -35.505 5.490 44.669 1.00 19.37 ? 420 GLU A CB 1 ATOM 3006 C CG . GLU A 1 400 ? -35.191 4.926 43.283 1.00 20.00 ? 420 GLU A CG 1 ATOM 3007 C CD . GLU A 1 400 ? -35.904 5.631 42.147 1.00 19.70 ? 420 GLU A CD 1 ATOM 3008 O OE1 . GLU A 1 400 ? -36.362 6.781 42.343 1.00 20.00 ? 420 GLU A OE1 1 ATOM 3009 O OE2 . GLU A 1 400 ? -35.993 5.028 41.047 1.00 19.61 ? 420 GLU A OE2 1 ATOM 3010 N N . MET A 1 401 ? -32.468 4.308 45.202 1.00 21.06 ? 421 MET A N 1 ATOM 3011 C CA . MET A 1 401 ? -31.063 4.642 45.129 1.00 21.60 ? 421 MET A CA 1 ATOM 3012 C C . MET A 1 401 ? -30.474 4.242 43.800 1.00 21.11 ? 421 MET A C 1 ATOM 3013 O O . MET A 1 401 ? -30.853 3.227 43.224 1.00 21.07 ? 421 MET A O 1 ATOM 3014 C CB . MET A 1 401 ? -30.272 3.977 46.249 1.00 22.22 ? 421 MET A CB 1 ATOM 3015 C CG . MET A 1 401 ? -30.225 2.475 46.228 1.00 23.57 ? 421 MET A CG 1 ATOM 3016 S SD . MET A 1 401 ? -28.869 1.907 47.279 1.00 28.73 ? 421 MET A SD 1 ATOM 3017 C CE . MET A 1 401 ? -27.496 1.817 46.115 1.00 28.25 ? 421 MET A CE 1 ATOM 3018 N N . PRO A 1 402 ? -29.531 5.043 43.309 1.00 21.00 ? 422 PRO A N 1 ATOM 3019 C CA . PRO A 1 402 ? -28.821 4.629 42.120 1.00 20.42 ? 422 PRO A CA 1 ATOM 3020 C C . PRO A 1 402 ? -27.931 3.445 42.446 1.00 19.98 ? 422 PRO A C 1 ATOM 3021 O O . PRO A 1 402 ? -27.262 3.441 43.474 1.00 18.99 ? 422 PRO A O 1 ATOM 3022 C CB . PRO A 1 402 ? -27.981 5.848 41.755 1.00 20.38 ? 422 PRO A CB 1 ATOM 3023 C CG . PRO A 1 402 ? -28.496 6.951 42.565 1.00 21.42 ? 422 PRO A CG 1 ATOM 3024 C CD . PRO A 1 402 ? -29.110 6.370 43.778 1.00 20.72 ? 422 PRO A CD 1 ATOM 3025 N N . THR A 1 403 ? -27.955 2.439 41.583 1.00 19.98 ? 423 THR A N 1 ATOM 3026 C CA . THR A 1 403 ? -27.132 1.251 41.767 1.00 20.00 ? 423 THR A CA 1 ATOM 3027 C C . THR A 1 403 ? -25.678 1.503 41.350 1.00 20.56 ? 423 THR A C 1 ATOM 3028 O O . THR A 1 403 ? -24.804 0.729 41.675 1.00 21.65 ? 423 THR A O 1 ATOM 3029 C CB . THR A 1 403 ? -27.666 0.114 40.917 1.00 19.68 ? 423 THR A CB 1 ATOM 3030 O OG1 . THR A 1 403 ? -27.632 0.518 39.546 1.00 19.20 ? 423 THR A OG1 1 ATOM 3031 C CG2 . THR A 1 403 ? -29.111 -0.245 41.320 1.00 18.39 ? 423 THR A CG2 1 ATOM 3032 N N . GLY A 1 404 ? -25.437 2.571 40.600 1.00 21.33 ? 424 GLY A N 1 ATOM 3033 C CA . GLY A 1 404 ? -24.124 2.857 40.039 1.00 21.52 ? 424 GLY A CA 1 ATOM 3034 C C . GLY A 1 404 ? -23.801 2.142 38.732 1.00 21.31 ? 424 GLY A C 1 ATOM 3035 O O . GLY A 1 404 ? -22.746 2.396 38.137 1.00 21.96 ? 424 GLY A O 1 ATOM 3036 N N . VAL A 1 405 ? -24.677 1.246 38.283 1.00 20.64 ? 425 VAL A N 1 ATOM 3037 C CA . VAL A 1 405 ? -24.481 0.544 37.013 1.00 20.16 ? 425 VAL A CA 1 ATOM 3038 C C . VAL A 1 405 ? -25.772 0.611 36.190 1.00 19.90 ? 425 VAL A C 1 ATOM 3039 O O . VAL A 1 405 ? -26.866 0.391 36.732 1.00 19.90 ? 425 VAL A O 1 ATOM 3040 C CB . VAL A 1 405 ? -24.055 -0.930 37.241 1.00 20.50 ? 425 VAL A CB 1 ATOM 3041 C CG1 . VAL A 1 405 ? -25.159 -1.723 37.930 1.00 19.91 ? 425 VAL A CG1 1 ATOM 3042 C CG2 . VAL A 1 405 ? -23.656 -1.591 35.920 1.00 19.53 ? 425 VAL A CG2 1 ATOM 3043 N N . PRO A 1 406 ? -25.662 0.932 34.885 1.00 19.16 ? 426 PRO A N 1 ATOM 3044 C CA . PRO A 1 406 ? -26.899 1.127 34.123 1.00 18.75 ? 426 PRO A CA 1 ATOM 3045 C C . PRO A 1 406 ? -27.719 -0.155 34.032 1.00 18.22 ? 426 PRO A C 1 ATOM 3046 O O . PRO A 1 406 ? -27.156 -1.239 34.068 1.00 17.83 ? 426 PRO A O 1 ATOM 3047 C CB . PRO A 1 406 ? -26.403 1.584 32.744 1.00 18.76 ? 426 PRO A CB 1 ATOM 3048 C CG . PRO A 1 406 ? -24.968 1.165 32.681 1.00 18.64 ? 426 PRO A CG 1 ATOM 3049 C CD . PRO A 1 406 ? -24.459 1.169 34.066 1.00 18.83 ? 426 PRO A CD 1 ATOM 3050 N N . LEU A 1 407 ? -29.046 -0.041 33.959 1.00 18.32 ? 427 LEU A N 1 ATOM 3051 C CA . LEU A 1 407 ? -29.893 -1.237 33.836 1.00 17.99 ? 427 LEU A CA 1 ATOM 3052 C C . LEU A 1 407 ? -29.601 -1.912 32.496 1.00 18.13 ? 427 LEU A C 1 ATOM 3053 O O . LEU A 1 407 ? -29.507 -3.137 32.405 1.00 17.90 ? 427 LEU A O 1 ATOM 3054 C CB . LEU A 1 407 ? -31.377 -0.890 33.985 1.00 18.02 ? 427 LEU A CB 1 ATOM 3055 C CG . LEU A 1 407 ? -32.331 -2.090 34.108 1.00 18.23 ? 427 LEU A CG 1 ATOM 3056 C CD1 . LEU A 1 407 ? -33.569 -1.742 34.934 1.00 19.91 ? 427 LEU A CD1 1 ATOM 3057 C CD2 . LEU A 1 407 ? -32.741 -2.596 32.731 1.00 19.19 ? 427 LEU A CD2 1 ATOM 3058 N N . ARG A 1 408 ? -29.443 -1.086 31.467 1.00 18.13 ? 428 ARG A N 1 ATOM 3059 C CA . ARG A 1 408 ? -29.003 -1.536 30.155 1.00 18.24 ? 428 ARG A CA 1 ATOM 3060 C C . ARG A 1 408 ? -28.287 -0.394 29.463 1.00 18.28 ? 428 ARG A C 1 ATOM 3061 O O . ARG A 1 408 ? -28.613 0.781 29.690 1.00 18.13 ? 428 ARG A O 1 ATOM 3062 C CB . ARG A 1 408 ? -30.191 -1.981 29.302 1.00 18.05 ? 428 ARG A CB 1 ATOM 3063 C CG . ARG A 1 408 ? -31.310 -0.946 29.193 1.00 17.58 ? 428 ARG A CG 1 ATOM 3064 C CD . ARG A 1 408 ? -32.446 -1.477 28.327 1.00 17.16 ? 428 ARG A CD 1 ATOM 3065 N NE . ARG A 1 408 ? -33.757 -1.076 28.835 1.00 17.17 ? 428 ARG A NE 1 ATOM 3066 C CZ . ARG A 1 408 ? -34.371 0.078 28.562 1.00 18.88 ? 428 ARG A CZ 1 ATOM 3067 N NH1 . ARG A 1 408 ? -33.809 0.991 27.772 1.00 17.96 ? 428 ARG A NH1 1 ATOM 3068 N NH2 . ARG A 1 408 ? -35.568 0.322 29.084 1.00 18.85 ? 428 ARG A NH2 1 ATOM 3069 N N . ARG A 1 409 ? -27.306 -0.741 28.635 1.00 18.06 ? 429 ARG A N 1 ATOM 3070 C CA . ARG A 1 409 ? -26.616 0.244 27.831 1.00 18.11 ? 429 ARG A CA 1 ATOM 3071 C C . ARG A 1 409 ? -26.031 -0.424 26.605 1.00 18.21 ? 429 ARG A C 1 ATOM 3072 O O . ARG A 1 409 ? -25.749 -1.621 26.615 1.00 17.81 ? 429 ARG A O 1 ATOM 3073 C CB . ARG A 1 409 ? -25.525 0.952 28.647 1.00 18.01 ? 429 ARG A CB 1 ATOM 3074 C CG . ARG A 1 409 ? -24.334 0.069 29.013 1.00 17.81 ? 429 ARG A CG 1 ATOM 3075 C CD . ARG A 1 409 ? -23.247 0.104 27.953 1.00 18.70 ? 429 ARG A CD 1 ATOM 3076 N NE . ARG A 1 409 ? -22.485 1.350 27.997 1.00 18.33 ? 429 ARG A NE 1 ATOM 3077 C CZ . ARG A 1 409 ? -21.457 1.638 27.200 1.00 19.14 ? 429 ARG A CZ 1 ATOM 3078 N NH1 . ARG A 1 409 ? -21.048 0.780 26.270 1.00 17.64 ? 429 ARG A NH1 1 ATOM 3079 N NH2 . ARG A 1 409 ? -20.831 2.802 27.330 1.00 19.45 ? 429 ARG A NH2 1 ATOM 3080 N N . HIS A 1 410 ? -25.868 0.362 25.548 1.00 18.51 ? 430 HIS A N 1 ATOM 3081 C CA . HIS A 1 410 ? -25.262 -0.111 24.326 1.00 18.95 ? 430 HIS A CA 1 ATOM 3082 C C . HIS A 1 410 ? -24.629 1.023 23.545 1.00 18.61 ? 430 HIS A C 1 ATOM 3083 O O . HIS A 1 410 ? -25.251 2.055 23.343 1.00 18.65 ? 430 HIS A O 1 ATOM 3084 C CB . HIS A 1 410 ? -26.299 -0.792 23.437 1.00 19.20 ? 430 HIS A CB 1 ATOM 3085 C CG . HIS A 1 410 ? -25.726 -1.296 22.150 1.00 20.02 ? 430 HIS A CG 1 ATOM 3086 N ND1 . HIS A 1 410 ? -24.811 -2.324 22.103 1.00 19.87 ? 430 HIS A ND1 1 ATOM 3087 C CD2 . HIS A 1 410 ? -25.920 -0.902 20.868 1.00 20.60 ? 430 HIS A CD2 1 ATOM 3088 C CE1 . HIS A 1 410 ? -24.476 -2.551 20.844 1.00 20.50 ? 430 HIS A CE1 1 ATOM 3089 N NE2 . HIS A 1 410 ? -25.139 -1.705 20.075 1.00 19.50 ? 430 HIS A NE2 1 ATOM 3090 N N . PHE A 1 411 ? -23.394 0.810 23.104 1.00 18.62 ? 431 PHE A N 1 ATOM 3091 C CA . PHE A 1 411 ? -22.725 1.687 22.147 1.00 18.71 ? 431 PHE A CA 1 ATOM 3092 C C . PHE A 1 411 ? -22.760 1.022 20.768 1.00 19.18 ? 431 PHE A C 1 ATOM 3093 O O . PHE A 1 411 ? -22.062 0.024 20.536 1.00 18.93 ? 431 PHE A O 1 ATOM 3094 C CB . PHE A 1 411 ? -21.272 1.902 22.572 1.00 18.81 ? 431 PHE A CB 1 ATOM 3095 C CG . PHE A 1 411 ? -20.525 2.876 21.708 1.00 19.35 ? 431 PHE A CG 1 ATOM 3096 C CD1 . PHE A 1 411 ? -19.728 2.433 20.659 1.00 21.47 ? 431 PHE A CD1 1 ATOM 3097 C CD2 . PHE A 1 411 ? -20.616 4.234 21.948 1.00 20.01 ? 431 PHE A CD2 1 ATOM 3098 C CE1 . PHE A 1 411 ? -19.019 3.341 19.856 1.00 21.32 ? 431 PHE A CE1 1 ATOM 3099 C CE2 . PHE A 1 411 ? -19.921 5.145 21.155 1.00 22.07 ? 431 PHE A CE2 1 ATOM 3100 C CZ . PHE A 1 411 ? -19.117 4.691 20.106 1.00 22.28 ? 431 PHE A CZ 1 ATOM 3101 N N . ASN A 1 412 ? -23.580 1.555 19.861 1.00 19.81 ? 432 ASN A N 1 ATOM 3102 C CA . ASN A 1 412 ? -23.706 0.991 18.518 1.00 20.44 ? 432 ASN A CA 1 ATOM 3103 C C . ASN A 1 412 ? -22.694 1.657 17.585 1.00 21.39 ? 432 ASN A C 1 ATOM 3104 O O . ASN A 1 412 ? -22.974 2.690 16.979 1.00 20.39 ? 432 ASN A O 1 ATOM 3105 C CB . ASN A 1 412 ? -25.134 1.151 17.973 1.00 20.36 ? 432 ASN A CB 1 ATOM 3106 C CG . ASN A 1 412 ? -25.442 0.155 16.860 1.00 20.24 ? 432 ASN A CG 1 ATOM 3107 O OD1 . ASN A 1 412 ? -25.646 0.527 15.707 1.00 20.31 ? 432 ASN A OD1 1 ATOM 3108 N ND2 . ASN A 1 412 ? -25.445 -1.117 17.203 1.00 19.12 ? 432 ASN A ND2 1 ATOM 3109 N N . SER A 1 413 ? -21.508 1.064 17.497 1.00 23.01 ? 433 SER A N 1 ATOM 3110 C CA . SER A 1 413 ? -20.415 1.636 16.723 1.00 24.26 ? 433 SER A CA 1 ATOM 3111 C C . SER A 1 413 ? -20.725 1.591 15.228 1.00 25.41 ? 433 SER A C 1 ATOM 3112 O O . SER A 1 413 ? -21.485 0.731 14.770 1.00 25.43 ? 433 SER A O 1 ATOM 3113 C CB . SER A 1 413 ? -19.127 0.869 17.009 1.00 24.82 ? 433 SER A CB 1 ATOM 3114 O OG . SER A 1 413 ? -18.048 1.366 16.232 1.00 25.30 ? 433 SER A OG 1 ATOM 3115 N N . ASN A 1 414 ? -20.163 2.530 14.471 1.00 26.51 ? 434 ASN A N 1 ATOM 3116 C CA . ASN A 1 414 ? -20.182 2.416 13.010 1.00 27.83 ? 434 ASN A CA 1 ATOM 3117 C C . ASN A 1 414 ? -18.863 1.843 12.481 1.00 28.76 ? 434 ASN A C 1 ATOM 3118 O O . ASN A 1 414 ? -18.670 1.745 11.284 1.00 29.55 ? 434 ASN A O 1 ATOM 3119 C CB . ASN A 1 414 ? -20.533 3.752 12.324 1.00 27.56 ? 434 ASN A CB 1 ATOM 3120 C CG . ASN A 1 414 ? -19.432 4.796 12.438 1.00 27.68 ? 434 ASN A CG 1 ATOM 3121 O OD1 . ASN A 1 414 ? -18.297 4.507 12.845 1.00 25.73 ? 434 ASN A OD1 1 ATOM 3122 N ND2 . ASN A 1 414 ? -19.767 6.026 12.076 1.00 26.92 ? 434 ASN A ND2 1 ATOM 3123 N N . PHE A 1 415 ? -17.950 1.494 13.382 1.00 30.21 ? 435 PHE A N 1 ATOM 3124 C CA . PHE A 1 415 ? -16.669 0.884 13.012 1.00 31.08 ? 435 PHE A CA 1 ATOM 3125 C C . PHE A 1 415 ? -15.870 1.755 12.034 1.00 31.45 ? 435 PHE A C 1 ATOM 3126 O O . PHE A 1 415 ? -14.995 1.261 11.330 1.00 32.09 ? 435 PHE A O 1 ATOM 3127 C CB . PHE A 1 415 ? -16.905 -0.533 12.438 1.00 31.42 ? 435 PHE A CB 1 ATOM 3128 C CG . PHE A 1 415 ? -17.936 -1.331 13.210 1.00 31.90 ? 435 PHE A CG 1 ATOM 3129 C CD1 . PHE A 1 415 ? -19.151 -1.668 12.632 1.00 32.70 ? 435 PHE A CD1 1 ATOM 3130 C CD2 . PHE A 1 415 ? -17.700 -1.694 14.530 1.00 33.86 ? 435 PHE A CD2 1 ATOM 3131 C CE1 . PHE A 1 415 ? -20.103 -2.374 13.339 1.00 32.97 ? 435 PHE A CE1 1 ATOM 3132 C CE2 . PHE A 1 415 ? -18.662 -2.403 15.261 1.00 33.94 ? 435 PHE A CE2 1 ATOM 3133 C CZ . PHE A 1 415 ? -19.860 -2.739 14.663 1.00 33.94 ? 435 PHE A CZ 1 ATOM 3134 N N . LYS A 1 416 ? -16.177 3.050 12.011 1.00 31.53 ? 436 LYS A N 1 ATOM 3135 C CA . LYS A 1 416 ? -15.527 4.008 11.127 1.00 31.40 ? 436 LYS A CA 1 ATOM 3136 C C . LYS A 1 416 ? -15.176 5.269 11.913 1.00 31.03 ? 436 LYS A C 1 ATOM 3137 O O . LYS A 1 416 ? -15.239 6.380 11.380 1.00 31.34 ? 436 LYS A O 1 ATOM 3138 C CB . LYS A 1 416 ? -16.458 4.364 9.957 1.00 31.49 ? 436 LYS A CB 1 ATOM 3139 N N . GLY A 1 417 ? -14.813 5.099 13.183 1.00 30.31 ? 437 GLY A N 1 ATOM 3140 C CA . GLY A 1 417 ? -14.453 6.235 14.040 1.00 29.78 ? 437 GLY A CA 1 ATOM 3141 C C . GLY A 1 417 ? -15.619 6.962 14.690 1.00 29.02 ? 437 GLY A C 1 ATOM 3142 O O . GLY A 1 417 ? -15.422 8.003 15.322 1.00 28.75 ? 437 GLY A O 1 ATOM 3143 N N . GLY A 1 418 ? -16.829 6.428 14.542 1.00 28.14 ? 438 GLY A N 1 ATOM 3144 C CA . GLY A 1 418 ? -18.016 7.052 15.119 1.00 27.38 ? 438 GLY A CA 1 ATOM 3145 C C . GLY A 1 418 ? -19.054 6.043 15.569 1.00 26.72 ? 438 GLY A C 1 ATOM 3146 O O . GLY A 1 418 ? -18.726 4.909 15.916 1.00 27.18 ? 438 GLY A O 1 ATOM 3147 N N . PHE A 1 419 ? -20.316 6.448 15.543 1.00 25.59 ? 439 PHE A N 1 ATOM 3148 C CA . PHE A 1 419 ? -21.383 5.611 16.061 1.00 24.81 ? 439 PHE A CA 1 ATOM 3149 C C . PHE A 1 419 ? -22.708 5.862 15.358 1.00 23.78 ? 439 PHE A C 1 ATOM 3150 O O . PHE A 1 419 ? -22.877 6.869 14.684 1.00 23.39 ? 439 PHE A O 1 ATOM 3151 C CB . PHE A 1 419 ? -21.496 5.775 17.588 1.00 24.98 ? 439 PHE A CB 1 ATOM 3152 C CG . PHE A 1 419 ? -22.177 7.053 18.058 1.00 25.15 ? 439 PHE A CG 1 ATOM 3153 C CD1 . PHE A 1 419 ? -23.029 7.012 19.152 1.00 25.11 ? 439 PHE A CD1 1 ATOM 3154 C CD2 . PHE A 1 419 ? -21.944 8.284 17.451 1.00 25.61 ? 439 PHE A CD2 1 ATOM 3155 C CE1 . PHE A 1 419 ? -23.655 8.162 19.619 1.00 26.16 ? 439 PHE A CE1 1 ATOM 3156 C CE2 . PHE A 1 419 ? -22.574 9.440 17.900 1.00 24.93 ? 439 PHE A CE2 1 ATOM 3157 C CZ . PHE A 1 419 ? -23.424 9.386 18.985 1.00 26.24 ? 439 PHE A CZ 1 ATOM 3158 N N . ASN A 1 420 ? -23.624 4.910 15.498 1.00 22.83 ? 440 ASN A N 1 ATOM 3159 C CA . ASN A 1 420 ? -24.994 5.052 15.004 1.00 22.19 ? 440 ASN A CA 1 ATOM 3160 C C . ASN A 1 420 ? -25.899 5.524 16.115 1.00 21.51 ? 440 ASN A C 1 ATOM 3161 O O . ASN A 1 420 ? -26.880 6.230 15.860 1.00 21.86 ? 440 ASN A O 1 ATOM 3162 C CB . ASN A 1 420 ? -25.505 3.721 14.469 1.00 22.35 ? 440 ASN A CB 1 ATOM 3163 C CG . ASN A 1 420 ? -24.605 3.145 13.388 1.00 22.75 ? 440 ASN A CG 1 ATOM 3164 O OD1 . ASN A 1 420 ? -24.184 3.857 12.475 1.00 23.01 ? 440 ASN A OD1 1 ATOM 3165 N ND2 . ASN A 1 420 ? -24.311 1.852 13.487 1.00 22.03 ? 440 ASN A ND2 1 ATOM 3166 N N . PHE A 1 421 ? -25.592 5.094 17.337 1.00 20.37 ? 441 PHE A N 1 ATOM 3167 C CA . PHE A 1 421 ? -26.236 5.628 18.531 1.00 19.87 ? 441 PHE A CA 1 ATOM 3168 C C . PHE A 1 421 ? -25.585 5.115 19.810 1.00 19.21 ? 441 PHE A C 1 ATOM 3169 O O . PHE A 1 421 ? -24.892 4.101 19.800 1.00 19.66 ? 441 PHE A O 1 ATOM 3170 C CB . PHE A 1 421 ? -27.758 5.329 18.541 1.00 19.87 ? 441 PHE A CB 1 ATOM 3171 C CG . PHE A 1 421 ? -28.105 3.867 18.699 1.00 19.04 ? 441 PHE A CG 1 ATOM 3172 C CD1 . PHE A 1 421 ? -28.288 3.055 17.587 1.00 18.41 ? 441 PHE A CD1 1 ATOM 3173 C CD2 . PHE A 1 421 ? -28.279 3.312 19.970 1.00 18.66 ? 441 PHE A CD2 1 ATOM 3174 C CE1 . PHE A 1 421 ? -28.615 1.716 17.741 1.00 19.57 ? 441 PHE A CE1 1 ATOM 3175 C CE2 . PHE A 1 421 ? -28.614 1.975 20.132 1.00 18.53 ? 441 PHE A CE2 1 ATOM 3176 C CZ . PHE A 1 421 ? -28.779 1.172 19.025 1.00 19.45 ? 441 PHE A CZ 1 ATOM 3177 N N . TYR A 1 422 ? -25.763 5.857 20.898 1.00 19.13 ? 442 TYR A N 1 ATOM 3178 C CA . TYR A 1 422 ? -25.608 5.307 22.248 1.00 18.83 ? 442 TYR A CA 1 ATOM 3179 C C . TYR A 1 422 ? -26.978 5.310 22.908 1.00 18.82 ? 442 TYR A C 1 ATOM 3180 O O . TYR A 1 422 ? -27.718 6.282 22.787 1.00 18.72 ? 442 TYR A O 1 ATOM 3181 C CB . TYR A 1 422 ? -24.646 6.123 23.103 1.00 18.83 ? 442 TYR A CB 1 ATOM 3182 C CG . TYR A 1 422 ? -24.724 5.760 24.568 1.00 18.11 ? 442 TYR A CG 1 ATOM 3183 C CD1 . TYR A 1 422 ? -23.948 4.740 25.090 1.00 18.94 ? 442 TYR A CD1 1 ATOM 3184 C CD2 . TYR A 1 422 ? -25.603 6.411 25.419 1.00 18.71 ? 442 TYR A CD2 1 ATOM 3185 C CE1 . TYR A 1 422 ? -24.028 4.391 26.423 1.00 19.25 ? 442 TYR A CE1 1 ATOM 3186 C CE2 . TYR A 1 422 ? -25.693 6.065 26.761 1.00 19.02 ? 442 TYR A CE2 1 ATOM 3187 C CZ . TYR A 1 422 ? -24.900 5.055 27.256 1.00 18.66 ? 442 TYR A CZ 1 ATOM 3188 O OH . TYR A 1 422 ? -24.982 4.700 28.583 1.00 18.66 ? 442 TYR A OH 1 ATOM 3189 N N . ALA A 1 423 ? -27.300 4.233 23.614 1.00 18.44 ? 443 ALA A N 1 ATOM 3190 C CA . ALA A 1 423 ? -28.541 4.153 24.383 1.00 18.83 ? 443 ALA A CA 1 ATOM 3191 C C . ALA A 1 423 ? -28.246 3.603 25.767 1.00 18.64 ? 443 ALA A C 1 ATOM 3192 O O . ALA A 1 423 ? -27.485 2.658 25.908 1.00 18.31 ? 443 ALA A O 1 ATOM 3193 C CB . ALA A 1 423 ? -29.588 3.276 23.680 1.00 17.80 ? 443 ALA A CB 1 ATOM 3194 N N . GLY A 1 424 ? -28.866 4.194 26.783 1.00 19.07 ? 444 GLY A N 1 ATOM 3195 C CA . GLY A 1 424 ? -28.669 3.736 28.152 1.00 19.27 ? 444 GLY A CA 1 ATOM 3196 C C . GLY A 1 424 ? -29.793 4.148 29.074 1.00 19.47 ? 444 GLY A C 1 ATOM 3197 O O . GLY A 1 424 ? -30.464 5.148 28.842 1.00 19.19 ? 444 GLY A O 1 ATOM 3198 N N . LEU A 1 425 ? -29.991 3.357 30.122 1.00 19.88 ? 445 LEU A N 1 ATOM 3199 C CA . LEU A 1 425 ? -30.957 3.660 31.165 1.00 20.11 ? 445 LEU A CA 1 ATOM 3200 C C . LEU A 1 425 ? -30.226 3.604 32.497 1.00 19.89 ? 445 LEU A C 1 ATOM 3201 O O . LEU A 1 425 ? -29.694 2.558 32.869 1.00 19.69 ? 445 LEU A O 1 ATOM 3202 C CB . LEU A 1 425 ? -32.128 2.668 31.116 1.00 20.10 ? 445 LEU A CB 1 ATOM 3203 C CG . LEU A 1 425 ? -33.120 2.645 32.290 1.00 20.94 ? 445 LEU A CG 1 ATOM 3204 C CD1 . LEU A 1 425 ? -33.674 4.014 32.603 1.00 21.04 ? 445 LEU A CD1 1 ATOM 3205 C CD2 . LEU A 1 425 ? -34.266 1.670 32.004 1.00 20.11 ? 445 LEU A CD2 1 ATOM 3206 N N . LYS A 1 426 ? -30.191 4.738 33.199 1.00 20.19 ? 446 LYS A N 1 ATOM 3207 C CA . LYS A 1 426 ? -29.511 4.859 34.492 1.00 20.55 ? 446 LYS A CA 1 ATOM 3208 C C . LYS A 1 426 ? -30.080 3.848 35.484 1.00 20.66 ? 446 LYS A C 1 ATOM 3209 O O . LYS A 1 426 ? -31.289 3.664 35.562 1.00 21.12 ? 446 LYS A O 1 ATOM 3210 C CB . LYS A 1 426 ? -29.662 6.280 35.054 1.00 20.34 ? 446 LYS A CB 1 ATOM 3211 C CG . LYS A 1 426 ? -29.032 6.517 36.418 1.00 21.72 ? 446 LYS A CG 1 ATOM 3212 C CD . LYS A 1 426 ? -29.239 7.963 36.914 1.00 23.01 ? 446 LYS A CD 1 ATOM 3213 C CE . LYS A 1 426 ? -28.635 8.155 38.300 1.00 24.27 ? 446 LYS A CE 1 ATOM 3214 N NZ . LYS A 1 426 ? -28.851 9.525 38.848 1.00 25.72 ? 446 LYS A NZ 1 ATOM 3215 N N . GLY A 1 427 ? -29.197 3.217 36.244 1.00 20.46 ? 447 GLY A N 1 ATOM 3216 C CA . GLY A 1 427 ? -29.588 2.207 37.211 1.00 20.36 ? 447 GLY A CA 1 ATOM 3217 C C . GLY A 1 427 ? -30.133 2.794 38.490 1.00 20.20 ? 447 GLY A C 1 ATOM 3218 O O . GLY A 1 427 ? -29.461 3.591 39.144 1.00 19.94 ? 447 GLY A O 1 ATOM 3219 N N . GLN A 1 428 ? -31.373 2.419 38.808 1.00 20.03 ? 448 GLN A N 1 ATOM 3220 C CA . GLN A 1 428 ? -32.022 2.733 40.074 1.00 20.05 ? 448 GLN A CA 1 ATOM 3221 C C . GLN A 1 428 ? -32.651 1.450 40.642 1.00 19.56 ? 448 GLN A C 1 ATOM 3222 O O . GLN A 1 428 ? -32.947 0.515 39.901 1.00 19.22 ? 448 GLN A O 1 ATOM 3223 C CB . GLN A 1 428 ? -33.132 3.780 39.882 1.00 20.51 ? 448 GLN A CB 1 ATOM 3224 C CG . GLN A 1 428 ? -32.676 5.163 39.374 1.00 21.04 ? 448 GLN A CG 1 ATOM 3225 C CD . GLN A 1 428 ? -32.127 6.082 40.479 1.00 23.41 ? 448 GLN A CD 1 ATOM 3226 O OE1 . GLN A 1 428 ? -31.988 5.677 41.640 1.00 24.43 ? 448 GLN A OE1 1 ATOM 3227 N NE2 . GLN A 1 428 ? -31.828 7.333 40.113 1.00 21.88 ? 448 GLN A NE2 1 ATOM 3228 N N . VAL A 1 429 ? -32.828 1.423 41.959 1.00 19.02 ? 449 VAL A N 1 ATOM 3229 C CA A VAL A 1 429 ? -33.541 0.341 42.639 0.60 18.77 ? 449 VAL A CA 1 ATOM 3230 C CA B VAL A 1 429 ? -33.566 0.354 42.614 0.40 18.88 ? 449 VAL A CA 1 ATOM 3231 C C . VAL A 1 429 ? -34.321 0.903 43.824 1.00 18.60 ? 449 VAL A C 1 ATOM 3232 O O . VAL A 1 429 ? -33.895 1.880 44.443 1.00 18.51 ? 449 VAL A O 1 ATOM 3233 C CB A VAL A 1 429 ? -32.579 -0.753 43.165 0.60 19.06 ? 449 VAL A CB 1 ATOM 3234 C CB B VAL A 1 429 ? -32.632 -0.799 43.040 0.40 19.09 ? 449 VAL A CB 1 ATOM 3235 C CG1 A VAL A 1 429 ? -32.038 -1.608 42.007 0.60 18.23 ? 449 VAL A CG1 1 ATOM 3236 C CG1 B VAL A 1 429 ? -32.046 -0.548 44.435 0.40 18.81 ? 449 VAL A CG1 1 ATOM 3237 C CG2 A VAL A 1 429 ? -31.444 -0.133 43.996 0.60 18.25 ? 449 VAL A CG2 1 ATOM 3238 C CG2 B VAL A 1 429 ? -33.378 -2.125 42.986 0.40 18.93 ? 449 VAL A CG2 1 ATOM 3239 N N . LEU A 1 430 ? -35.454 0.280 44.134 1.00 18.04 ? 450 LEU A N 1 ATOM 3240 C CA . LEU A 1 430 ? -36.242 0.618 45.314 1.00 17.20 ? 450 LEU A CA 1 ATOM 3241 C C . LEU A 1 430 ? -35.851 -0.374 46.400 1.00 16.94 ? 450 LEU A C 1 ATOM 3242 O O . LEU A 1 430 ? -35.782 -1.571 46.138 1.00 16.95 ? 450 LEU A O 1 ATOM 3243 C CB . LEU A 1 430 ? -37.725 0.474 45.020 1.00 16.95 ? 450 LEU A CB 1 ATOM 3244 C CG . LEU A 1 430 ? -38.674 0.723 46.195 1.00 17.03 ? 450 LEU A CG 1 ATOM 3245 C CD1 . LEU A 1 430 ? -38.690 2.226 46.540 1.00 16.44 ? 450 LEU A CD1 1 ATOM 3246 C CD2 . LEU A 1 430 ? -40.085 0.209 45.862 1.00 15.24 ? 450 LEU A CD2 1 ATOM 3247 N N . VAL A 1 431 ? -35.618 0.117 47.615 1.00 16.51 ? 451 VAL A N 1 ATOM 3248 C CA . VAL A 1 431 ? -35.194 -0.729 48.717 1.00 16.30 ? 451 VAL A CA 1 ATOM 3249 C C . VAL A 1 431 ? -36.120 -0.537 49.911 1.00 16.72 ? 451 VAL A C 1 ATOM 3250 O O . VAL A 1 431 ? -36.288 0.584 50.380 1.00 16.54 ? 451 VAL A O 1 ATOM 3251 C CB . VAL A 1 431 ? -33.773 -0.380 49.171 1.00 16.52 ? 451 VAL A CB 1 ATOM 3252 C CG1 . VAL A 1 431 ? -33.364 -1.247 50.382 1.00 16.01 ? 451 VAL A CG1 1 ATOM 3253 C CG2 . VAL A 1 431 ? -32.800 -0.519 48.016 1.00 15.41 ? 451 VAL A CG2 1 ATOM 3254 N N . LEU A 1 432 ? -36.707 -1.645 50.378 1.00 16.96 ? 452 LEU A N 1 ATOM 3255 C CA . LEU A 1 432 ? -37.455 -1.718 51.635 1.00 17.09 ? 452 LEU A CA 1 ATOM 3256 C C . LEU A 1 432 ? -36.572 -2.437 52.621 1.00 16.76 ? 452 LEU A C 1 ATOM 3257 O O . LEU A 1 432 ? -36.159 -3.572 52.375 1.00 16.96 ? 452 LEU A O 1 ATOM 3258 C CB . LEU A 1 432 ? -38.755 -2.518 51.459 1.00 17.46 ? 452 LEU A CB 1 ATOM 3259 C CG . LEU A 1 432 ? -39.614 -2.739 52.711 1.00 17.51 ? 452 LEU A CG 1 ATOM 3260 C CD1 . LEU A 1 432 ? -40.120 -1.397 53.255 1.00 17.02 ? 452 LEU A CD1 1 ATOM 3261 C CD2 . LEU A 1 432 ? -40.780 -3.701 52.412 1.00 16.86 ? 452 LEU A CD2 1 ATOM 3262 N N . ARG A 1 433 ? -36.318 -1.800 53.758 1.00 16.31 ? 453 ARG A N 1 ATOM 3263 C CA . ARG A 1 433 ? -35.339 -2.292 54.699 1.00 15.81 ? 453 ARG A CA 1 ATOM 3264 C C . ARG A 1 433 ? -35.829 -2.201 56.125 1.00 16.10 ? 453 ARG A C 1 ATOM 3265 O O . ARG A 1 433 ? -36.504 -1.239 56.514 1.00 16.10 ? 453 ARG A O 1 ATOM 3266 C CB . ARG A 1 433 ? -34.041 -1.487 54.565 1.00 15.67 ? 453 ARG A CB 1 ATOM 3267 C CG . ARG A 1 433 ? -32.991 -1.782 55.642 1.00 16.58 ? 453 ARG A CG 1 ATOM 3268 C CD . ARG A 1 433 ? -31.706 -1.030 55.332 1.00 17.98 ? 453 ARG A CD 1 ATOM 3269 N NE . ARG A 1 433 ? -31.086 -1.549 54.120 1.00 16.92 ? 453 ARG A NE 1 ATOM 3270 C CZ . ARG A 1 433 ? -30.169 -0.909 53.399 1.00 18.05 ? 453 ARG A CZ 1 ATOM 3271 N NH1 . ARG A 1 433 ? -29.756 0.303 53.733 1.00 16.87 ? 453 ARG A NH1 1 ATOM 3272 N NH2 . ARG A 1 433 ? -29.665 -1.496 52.316 1.00 18.71 ? 453 ARG A NH2 1 ATOM 3273 N N . THR A 1 434 ? -35.472 -3.211 56.908 1.00 16.48 ? 454 THR A N 1 ATOM 3274 C CA . THR A 1 434 ? -35.524 -3.109 58.357 1.00 16.70 ? 454 THR A CA 1 ATOM 3275 C C . THR A 1 434 ? -34.269 -3.783 58.896 1.00 17.30 ? 454 THR A C 1 ATOM 3276 O O . THR A 1 434 ? -33.396 -4.212 58.127 1.00 17.26 ? 454 THR A O 1 ATOM 3277 C CB . THR A 1 434 ? -36.840 -3.715 58.945 1.00 16.97 ? 454 THR A CB 1 ATOM 3278 O OG1 . THR A 1 434 ? -36.950 -3.388 60.338 1.00 15.93 ? 454 THR A OG1 1 ATOM 3279 C CG2 . THR A 1 434 ? -36.885 -5.225 58.773 1.00 15.82 ? 454 THR A CG2 1 ATOM 3280 N N . THR A 1 435 ? -34.167 -3.859 60.212 1.00 17.81 ? 455 THR A N 1 ATOM 3281 C CA . THR A 1 435 ? -33.046 -4.504 60.854 1.00 18.33 ? 455 THR A CA 1 ATOM 3282 C C . THR A 1 435 ? -33.560 -5.373 61.993 1.00 19.21 ? 455 THR A C 1 ATOM 3283 O O . THR A 1 435 ? -34.723 -5.261 62.407 1.00 18.85 ? 455 THR A O 1 ATOM 3284 C CB . THR A 1 435 ? -32.061 -3.462 61.441 1.00 18.61 ? 455 THR A CB 1 ATOM 3285 O OG1 . THR A 1 435 ? -32.715 -2.706 62.471 1.00 19.09 ? 455 THR A OG1 1 ATOM 3286 C CG2 . THR A 1 435 ? -31.545 -2.510 60.358 1.00 17.80 ? 455 THR A CG2 1 ATOM 3287 N N . SER A 1 436 ? -32.695 -6.241 62.493 1.00 19.50 ? 456 SER A N 1 ATOM 3288 C CA . SER A 1 436 ? -32.974 -6.950 63.723 1.00 20.39 ? 456 SER A CA 1 ATOM 3289 C C . SER A 1 436 ? -31.690 -6.995 64.537 1.00 20.92 ? 456 SER A C 1 ATOM 3290 O O . SER A 1 436 ? -30.660 -7.512 64.081 1.00 20.69 ? 456 SER A O 1 ATOM 3291 C CB . SER A 1 436 ? -33.549 -8.343 63.458 1.00 20.44 ? 456 SER A CB 1 ATOM 3292 O OG . SER A 1 436 ? -32.657 -9.140 62.722 1.00 22.81 ? 456 SER A OG 1 ATOM 3293 N N . THR A 1 437 ? -31.748 -6.375 65.714 1.00 21.65 ? 457 THR A N 1 ATOM 3294 C CA . THR A 1 437 ? -30.652 -6.400 66.669 1.00 22.51 ? 457 THR A CA 1 ATOM 3295 C C . THR A 1 437 ? -31.188 -7.003 67.956 1.00 23.63 ? 457 THR A C 1 ATOM 3296 O O . THR A 1 437 ? -31.661 -6.278 68.829 1.00 23.84 ? 457 THR A O 1 ATOM 3297 C CB . THR A 1 437 ? -30.129 -4.993 66.983 1.00 22.24 ? 457 THR A CB 1 ATOM 3298 O OG1 . THR A 1 437 ? -29.862 -4.280 65.771 1.00 23.14 ? 457 THR A OG1 1 ATOM 3299 C CG2 . THR A 1 437 ? -28.859 -5.066 67.835 1.00 21.79 ? 457 THR A CG2 1 ATOM 3300 N N . VAL A 1 438 ? -31.139 -8.322 68.077 1.00 24.81 ? 458 VAL A N 1 ATOM 3301 C CA . VAL A 1 438 ? -31.616 -8.981 69.303 1.00 25.65 ? 458 VAL A CA 1 ATOM 3302 C C . VAL A 1 438 ? -30.661 -8.694 70.466 1.00 26.09 ? 458 VAL A C 1 ATOM 3303 O O . VAL A 1 438 ? -31.094 -8.461 71.610 1.00 27.36 ? 458 VAL A O 1 ATOM 3304 C CB . VAL A 1 438 ? -31.759 -10.510 69.120 1.00 26.12 ? 458 VAL A CB 1 ATOM 3305 N N . TYR A 1 439 ? -29.367 -8.687 70.172 1.00 25.77 ? 459 TYR A N 1 ATOM 3306 C CA . TYR A 1 439 ? -28.360 -8.549 71.203 1.00 25.88 ? 459 TYR A CA 1 ATOM 3307 C C . TYR A 1 439 ? -27.025 -8.118 70.609 1.00 25.31 ? 459 TYR A C 1 ATOM 3308 O O . TYR A 1 439 ? -26.770 -6.922 70.505 1.00 25.68 ? 459 TYR A O 1 ATOM 3309 C CB . TYR A 1 439 ? -28.254 -9.872 71.957 1.00 26.30 ? 459 TYR A CB 1 ATOM 3310 C CG . TYR A 1 439 ? -27.413 -9.872 73.201 1.00 28.56 ? 459 TYR A CG 1 ATOM 3311 C CD1 . TYR A 1 439 ? -27.801 -9.145 74.325 1.00 30.25 ? 459 TYR A CD1 1 ATOM 3312 C CD2 . TYR A 1 439 ? -26.255 -10.661 73.287 1.00 31.18 ? 459 TYR A CD2 1 ATOM 3313 C CE1 . TYR A 1 439 ? -27.043 -9.184 75.507 1.00 32.28 ? 459 TYR A CE1 1 ATOM 3314 C CE2 . TYR A 1 439 ? -25.495 -10.708 74.456 1.00 30.78 ? 459 TYR A CE2 1 ATOM 3315 C CZ . TYR A 1 439 ? -25.891 -9.970 75.557 1.00 32.79 ? 459 TYR A CZ 1 ATOM 3316 O OH . TYR A 1 439 ? -25.143 -10.018 76.707 1.00 33.99 ? 459 TYR A OH 1 ATOM 3317 N N . ASN A 1 440 ? -26.192 -9.068 70.191 1.00 24.98 ? 460 ASN A N 1 ATOM 3318 C CA . ASN A 1 440 ? -24.832 -8.749 69.714 1.00 24.47 ? 460 ASN A CA 1 ATOM 3319 C C . ASN A 1 440 ? -24.770 -8.400 68.227 1.00 24.03 ? 460 ASN A C 1 ATOM 3320 O O . ASN A 1 440 ? -24.134 -7.423 67.855 1.00 23.87 ? 460 ASN A O 1 ATOM 3321 C CB . ASN A 1 440 ? -23.843 -9.879 70.041 1.00 24.24 ? 460 ASN A CB 1 ATOM 3322 C CG . ASN A 1 440 ? -24.256 -11.223 69.467 1.00 24.63 ? 460 ASN A CG 1 ATOM 3323 O OD1 . ASN A 1 440 ? -25.314 -11.756 69.809 1.00 25.40 ? 460 ASN A OD1 1 ATOM 3324 N ND2 . ASN A 1 440 ? -23.403 -11.798 68.614 1.00 23.69 ? 460 ASN A ND2 1 HETATM 3325 N N . TPQ A 1 441 ? -25.435 -9.203 67.395 1.00 23.53 ? 461 TPQ A N 1 HETATM 3326 C CA . TPQ A 1 441 ? -25.452 -9.018 65.941 1.00 23.64 ? 461 TPQ A CA 1 HETATM 3327 C CB . TPQ A 1 441 ? -25.780 -10.357 65.252 1.00 24.37 ? 461 TPQ A CB 1 HETATM 3328 C C . TPQ A 1 441 ? -26.546 -8.083 65.444 1.00 22.83 ? 461 TPQ A C 1 HETATM 3329 O O . TPQ A 1 441 ? -27.610 -7.989 66.050 1.00 23.09 ? 461 TPQ A O 1 HETATM 3330 C C1 . TPQ A 1 441 ? -24.560 -11.152 64.868 1.00 25.56 ? 461 TPQ A C1 1 HETATM 3331 C C2 . TPQ A 1 441 ? -24.426 -12.551 65.332 1.00 25.96 ? 461 TPQ A C2 1 HETATM 3332 O O2 . TPQ A 1 441 ? -25.300 -13.083 66.050 0.50 25.32 ? 461 TPQ A O2 1 HETATM 3333 C C3 . TPQ A 1 441 ? -23.220 -13.316 64.917 1.00 27.15 ? 461 TPQ A C3 1 HETATM 3334 C C4 . TPQ A 1 441 ? -22.238 -12.743 64.101 1.00 26.59 ? 461 TPQ A C4 1 HETATM 3335 O O4 . TPQ A 1 441 ? -21.235 -13.385 63.764 1.00 24.85 ? 461 TPQ A O4 1 HETATM 3336 C C5 . TPQ A 1 441 ? -22.372 -11.349 63.641 1.00 27.40 ? 461 TPQ A C5 1 HETATM 3337 O O5 . TPQ A 1 441 ? -21.489 -10.843 62.914 0.50 27.82 ? 461 TPQ A O5 1 HETATM 3338 C C6 . TPQ A 1 441 ? -23.581 -10.581 64.051 1.00 26.98 ? 461 TPQ A C6 1 ATOM 3339 N N . ASP A 1 442 ? -26.292 -7.418 64.321 1.00 22.23 ? 462 ASP A N 1 ATOM 3340 C CA . ASP A 1 442 ? -27.304 -6.635 63.632 1.00 21.52 ? 462 ASP A CA 1 ATOM 3341 C C . ASP A 1 442 ? -27.486 -7.211 62.238 1.00 21.21 ? 462 ASP A C 1 ATOM 3342 O O . ASP A 1 442 ? -26.556 -7.202 61.427 1.00 21.47 ? 462 ASP A O 1 ATOM 3343 C CB . ASP A 1 442 ? -26.909 -5.165 63.519 1.00 21.54 ? 462 ASP A CB 1 ATOM 3344 C CG . ASP A 1 442 ? -26.744 -4.491 64.862 1.00 21.66 ? 462 ASP A CG 1 ATOM 3345 O OD1 . ASP A 1 442 ? -25.853 -4.916 65.623 1.00 20.54 ? 462 ASP A OD1 1 ATOM 3346 O OD2 . ASP A 1 442 ? -27.486 -3.515 65.136 1.00 21.93 ? 462 ASP A OD2 1 ATOM 3347 N N . TYR A 1 443 ? -28.671 -7.756 61.978 1.00 20.53 ? 463 TYR A N 1 ATOM 3348 C CA A TYR A 1 443 ? -28.975 -8.167 60.630 0.50 20.10 ? 463 TYR A CA 1 ATOM 3349 C CA B TYR A 1 443 ? -29.090 -8.214 60.643 0.50 20.07 ? 463 TYR A CA 1 ATOM 3350 C C . TYR A 1 443 ? -29.731 -7.045 59.922 1.00 19.72 ? 463 TYR A C 1 ATOM 3351 O O . TYR A 1 443 ? -30.580 -6.360 60.513 1.00 19.23 ? 463 TYR A O 1 ATOM 3352 C CB A TYR A 1 443 ? -29.698 -9.505 60.641 0.50 19.92 ? 463 TYR A CB 1 ATOM 3353 C CB B TYR A 1 443 ? -30.209 -9.258 60.707 0.50 19.95 ? 463 TYR A CB 1 ATOM 3354 C CG A TYR A 1 443 ? -28.857 -10.558 61.334 0.50 20.80 ? 463 TYR A CG 1 ATOM 3355 C CG B TYR A 1 443 ? -29.922 -10.623 61.280 0.50 20.52 ? 463 TYR A CG 1 ATOM 3356 C CD1 A TYR A 1 443 ? -27.721 -11.079 60.728 0.50 20.87 ? 463 TYR A CD1 1 ATOM 3357 C CD1 B TYR A 1 443 ? -29.449 -11.648 60.480 0.50 20.64 ? 463 TYR A CD1 1 ATOM 3358 C CD2 A TYR A 1 443 ? -29.162 -10.986 62.619 0.50 22.00 ? 463 TYR A CD2 1 ATOM 3359 C CD2 B TYR A 1 443 ? -30.226 -10.917 62.600 0.50 21.29 ? 463 TYR A CD2 1 ATOM 3360 C CE1 A TYR A 1 443 ? -26.938 -12.025 61.364 0.50 21.26 ? 463 TYR A CE1 1 ATOM 3361 C CE1 B TYR A 1 443 ? -29.229 -12.912 60.990 0.50 20.50 ? 463 TYR A CE1 1 ATOM 3362 C CE2 A TYR A 1 443 ? -28.381 -11.932 63.263 0.50 22.27 ? 463 TYR A CE2 1 ATOM 3363 C CE2 B TYR A 1 443 ? -30.011 -12.173 63.116 0.50 21.29 ? 463 TYR A CE2 1 ATOM 3364 C CZ A TYR A 1 443 ? -27.275 -12.448 62.630 0.50 21.75 ? 463 TYR A CZ 1 ATOM 3365 C CZ B TYR A 1 443 ? -29.514 -13.170 62.305 0.50 21.12 ? 463 TYR A CZ 1 ATOM 3366 O OH A TYR A 1 443 ? -26.511 -13.391 63.275 0.50 22.30 ? 463 TYR A OH 1 ATOM 3367 O OH B TYR A 1 443 ? -29.294 -14.429 62.816 0.50 21.74 ? 463 TYR A OH 1 ATOM 3368 N N . ILE A 1 444 ? -29.381 -6.846 58.659 1.00 19.08 ? 464 ILE A N 1 ATOM 3369 C CA . ILE A 1 444 ? -30.029 -5.860 57.815 1.00 18.63 ? 464 ILE A CA 1 ATOM 3370 C C . ILE A 1 444 ? -30.832 -6.626 56.754 1.00 18.75 ? 464 ILE A C 1 ATOM 3371 O O . ILE A 1 444 ? -30.273 -7.416 55.993 1.00 18.04 ? 464 ILE A O 1 ATOM 3372 C CB . ILE A 1 444 ? -28.989 -4.930 57.158 1.00 18.82 ? 464 ILE A CB 1 ATOM 3373 C CG1 . ILE A 1 444 ? -28.052 -4.342 58.229 1.00 19.21 ? 464 ILE A CG1 1 ATOM 3374 C CG2 . ILE A 1 444 ? -29.678 -3.809 56.343 1.00 17.57 ? 464 ILE A CG2 1 ATOM 3375 C CD1 . ILE A 1 444 ? -27.025 -3.325 57.684 1.00 18.04 ? 464 ILE A CD1 1 ATOM 3376 N N . TRP A 1 445 ? -32.144 -6.388 56.717 1.00 18.67 ? 465 TRP A N 1 ATOM 3377 C CA . TRP A 1 445 ? -33.052 -7.130 55.850 1.00 18.40 ? 465 TRP A CA 1 ATOM 3378 C C . TRP A 1 445 ? -33.564 -6.222 54.747 1.00 18.54 ? 465 TRP A C 1 ATOM 3379 O O . TRP A 1 445 ? -34.246 -5.238 55.035 1.00 18.61 ? 465 TRP A O 1 ATOM 3380 C CB . TRP A 1 445 ? -34.263 -7.627 56.648 1.00 18.32 ? 465 TRP A CB 1 ATOM 3381 C CG . TRP A 1 445 ? -33.917 -8.498 57.800 1.00 18.76 ? 465 TRP A CG 1 ATOM 3382 C CD1 . TRP A 1 445 ? -33.873 -8.134 59.112 1.00 18.25 ? 465 TRP A CD1 1 ATOM 3383 C CD2 . TRP A 1 445 ? -33.573 -9.884 57.751 1.00 17.90 ? 465 TRP A CD2 1 ATOM 3384 N NE1 . TRP A 1 445 ? -33.520 -9.207 59.883 1.00 19.49 ? 465 TRP A NE1 1 ATOM 3385 C CE2 . TRP A 1 445 ? -33.333 -10.298 59.075 1.00 18.10 ? 465 TRP A CE2 1 ATOM 3386 C CE3 . TRP A 1 445 ? -33.448 -10.822 56.711 1.00 18.88 ? 465 TRP A CE3 1 ATOM 3387 C CZ2 . TRP A 1 445 ? -32.967 -11.615 59.401 1.00 17.45 ? 465 TRP A CZ2 1 ATOM 3388 C CZ3 . TRP A 1 445 ? -33.089 -12.147 57.039 1.00 18.63 ? 465 TRP A CZ3 1 ATOM 3389 C CH2 . TRP A 1 445 ? -32.861 -12.524 58.374 1.00 17.22 ? 465 TRP A CH2 1 ATOM 3390 N N . ASP A 1 446 ? -33.259 -6.567 53.497 1.00 18.37 ? 466 ASP A N 1 ATOM 3391 C CA . ASP A 1 446 ? -33.689 -5.787 52.347 1.00 18.62 ? 466 ASP A CA 1 ATOM 3392 C C . ASP A 1 446 ? -34.596 -6.608 51.445 1.00 18.44 ? 466 ASP A C 1 ATOM 3393 O O . ASP A 1 446 ? -34.387 -7.816 51.248 1.00 18.62 ? 466 ASP A O 1 ATOM 3394 C CB . ASP A 1 446 ? -32.501 -5.345 51.482 1.00 18.65 ? 466 ASP A CB 1 ATOM 3395 C CG . ASP A 1 446 ? -31.513 -4.463 52.210 1.00 19.23 ? 466 ASP A CG 1 ATOM 3396 O OD1 . ASP A 1 446 ? -31.778 -3.976 53.340 1.00 19.03 ? 466 ASP A OD1 1 ATOM 3397 O OD2 . ASP A 1 446 ? -30.441 -4.251 51.615 1.00 18.07 ? 466 ASP A OD2 1 ATOM 3398 N N . PHE A 1 447 ? -35.595 -5.927 50.896 1.00 18.05 ? 467 PHE A N 1 ATOM 3399 C CA . PHE A 1 447 ? -36.308 -6.387 49.728 1.00 17.74 ? 467 PHE A CA 1 ATOM 3400 C C . PHE A 1 447 ? -36.130 -5.280 48.703 1.00 17.66 ? 467 PHE A C 1 ATOM 3401 O O . PHE A 1 447 ? -36.383 -4.105 48.991 1.00 17.02 ? 467 PHE A O 1 ATOM 3402 C CB . PHE A 1 447 ? -37.781 -6.653 50.050 1.00 18.02 ? 467 PHE A CB 1 ATOM 3403 C CG . PHE A 1 447 ? -38.000 -7.902 50.880 1.00 19.38 ? 467 PHE A CG 1 ATOM 3404 C CD1 . PHE A 1 447 ? -38.529 -7.825 52.163 1.00 20.85 ? 467 PHE A CD1 1 ATOM 3405 C CD2 . PHE A 1 447 ? -37.656 -9.149 50.382 1.00 18.69 ? 467 PHE A CD2 1 ATOM 3406 C CE1 . PHE A 1 447 ? -38.738 -8.974 52.921 1.00 20.76 ? 467 PHE A CE1 1 ATOM 3407 C CE2 . PHE A 1 447 ? -37.842 -10.305 51.146 1.00 19.85 ? 467 PHE A CE2 1 ATOM 3408 C CZ . PHE A 1 447 ? -38.385 -10.220 52.412 1.00 19.69 ? 467 PHE A CZ 1 ATOM 3409 N N . ILE A 1 448 ? -35.664 -5.665 47.521 1.00 17.45 ? 468 ILE A N 1 ATOM 3410 C CA . ILE A 1 448 ? -35.176 -4.740 46.524 1.00 17.97 ? 468 ILE A CA 1 ATOM 3411 C C . ILE A 1 448 ? -35.965 -4.946 45.236 1.00 17.74 ? 468 ILE A C 1 ATOM 3412 O O . ILE A 1 448 ? -36.194 -6.085 44.811 1.00 17.75 ? 468 ILE A O 1 ATOM 3413 C CB . ILE A 1 448 ? -33.679 -5.003 46.257 1.00 18.11 ? 468 ILE A CB 1 ATOM 3414 C CG1 . ILE A 1 448 ? -32.850 -4.761 47.527 1.00 19.89 ? 468 ILE A CG1 1 ATOM 3415 C CG2 . ILE A 1 448 ? -33.172 -4.139 45.139 1.00 19.33 ? 468 ILE A CG2 1 ATOM 3416 C CD1 . ILE A 1 448 ? -31.477 -5.485 47.483 1.00 21.69 ? 468 ILE A CD1 1 ATOM 3417 N N . PHE A 1 449 ? -36.356 -3.848 44.599 1.00 17.58 ? 469 PHE A N 1 ATOM 3418 C CA . PHE A 1 449 ? -37.204 -3.920 43.418 1.00 17.72 ? 469 PHE A CA 1 ATOM 3419 C C . PHE A 1 449 ? -36.592 -3.120 42.283 1.00 17.77 ? 469 PHE A C 1 ATOM 3420 O O . PHE A 1 449 ? -36.370 -1.923 42.407 1.00 17.75 ? 469 PHE A O 1 ATOM 3421 C CB . PHE A 1 449 ? -38.620 -3.424 43.742 1.00 17.79 ? 469 PHE A CB 1 ATOM 3422 C CG . PHE A 1 449 ? -39.268 -4.160 44.879 1.00 16.73 ? 469 PHE A CG 1 ATOM 3423 C CD1 . PHE A 1 449 ? -39.043 -3.770 46.182 1.00 16.72 ? 469 PHE A CD1 1 ATOM 3424 C CD2 . PHE A 1 449 ? -40.098 -5.241 44.642 1.00 17.64 ? 469 PHE A CD2 1 ATOM 3425 C CE1 . PHE A 1 449 ? -39.636 -4.453 47.240 1.00 17.68 ? 469 PHE A CE1 1 ATOM 3426 C CE2 . PHE A 1 449 ? -40.678 -5.934 45.693 1.00 16.23 ? 469 PHE A CE2 1 ATOM 3427 C CZ . PHE A 1 449 ? -40.453 -5.531 46.988 1.00 16.06 ? 469 PHE A CZ 1 ATOM 3428 N N . TYR A 1 450 ? -36.307 -3.811 41.182 1.00 18.14 ? 470 TYR A N 1 ATOM 3429 C CA . TYR A 1 450 ? -35.641 -3.227 40.027 1.00 17.98 ? 470 TYR A CA 1 ATOM 3430 C C . TYR A 1 450 ? -36.709 -2.859 39.015 1.00 17.80 ? 470 TYR A C 1 ATOM 3431 O O . TYR A 1 450 ? -37.746 -3.512 38.966 1.00 17.58 ? 470 TYR A O 1 ATOM 3432 C CB . TYR A 1 450 ? -34.703 -4.228 39.381 1.00 18.20 ? 470 TYR A CB 1 ATOM 3433 C CG . TYR A 1 450 ? -33.486 -4.631 40.183 1.00 19.09 ? 470 TYR A CG 1 ATOM 3434 C CD1 . TYR A 1 450 ? -33.582 -5.570 41.190 1.00 19.98 ? 470 TYR A CD1 1 ATOM 3435 C CD2 . TYR A 1 450 ? -32.223 -4.112 39.886 1.00 20.70 ? 470 TYR A CD2 1 ATOM 3436 C CE1 . TYR A 1 450 ? -32.465 -5.976 41.907 1.00 20.99 ? 470 TYR A CE1 1 ATOM 3437 C CE2 . TYR A 1 450 ? -31.084 -4.516 40.605 1.00 21.98 ? 470 TYR A CE2 1 ATOM 3438 C CZ . TYR A 1 450 ? -31.220 -5.448 41.609 1.00 22.34 ? 470 TYR A CZ 1 ATOM 3439 O OH . TYR A 1 450 ? -30.123 -5.878 42.319 1.00 23.34 ? 470 TYR A OH 1 ATOM 3440 N N . PRO A 1 451 ? -36.469 -1.807 38.205 1.00 17.72 ? 471 PRO A N 1 ATOM 3441 C CA . PRO A 1 451 ? -37.500 -1.321 37.279 1.00 17.70 ? 471 PRO A CA 1 ATOM 3442 C C . PRO A 1 451 ? -37.883 -2.305 36.171 1.00 17.60 ? 471 PRO A C 1 ATOM 3443 O O . PRO A 1 451 ? -38.929 -2.127 35.541 1.00 17.69 ? 471 PRO A O 1 ATOM 3444 C CB . PRO A 1 451 ? -36.861 -0.056 36.684 1.00 17.62 ? 471 PRO A CB 1 ATOM 3445 C CG . PRO A 1 451 ? -35.885 0.387 37.740 1.00 18.25 ? 471 PRO A CG 1 ATOM 3446 C CD . PRO A 1 451 ? -35.301 -0.908 38.213 1.00 17.88 ? 471 PRO A CD 1 ATOM 3447 N N . ASN A 1 452 ? -37.044 -3.323 35.941 1.00 17.52 ? 472 ASN A N 1 ATOM 3448 C CA . ASN A 1 452 ? -37.333 -4.379 34.965 1.00 17.43 ? 472 ASN A CA 1 ATOM 3449 C C . ASN A 1 452 ? -38.015 -5.634 35.544 1.00 17.36 ? 472 ASN A C 1 ATOM 3450 O O . ASN A 1 452 ? -37.975 -6.699 34.929 1.00 17.44 ? 472 ASN A O 1 ATOM 3451 C CB . ASN A 1 452 ? -36.054 -4.762 34.207 1.00 17.21 ? 472 ASN A CB 1 ATOM 3452 C CG . ASN A 1 452 ? -35.062 -5.543 35.063 1.00 17.35 ? 472 ASN A CG 1 ATOM 3453 O OD1 . ASN A 1 452 ? -35.118 -5.506 36.297 1.00 16.69 ? 472 ASN A OD1 1 ATOM 3454 N ND2 . ASN A 1 452 ? -34.143 -6.248 34.404 1.00 12.96 ? 472 ASN A ND2 1 ATOM 3455 N N . GLY A 1 453 ? -38.650 -5.519 36.707 1.00 17.15 ? 473 GLY A N 1 ATOM 3456 C CA . GLY A 1 453 ? -39.458 -6.638 37.245 1.00 17.22 ? 473 GLY A CA 1 ATOM 3457 C C . GLY A 1 453 ? -38.684 -7.695 38.038 1.00 16.89 ? 473 GLY A C 1 ATOM 3458 O O . GLY A 1 453 ? -39.245 -8.721 38.443 1.00 16.58 ? 473 GLY A O 1 ATOM 3459 N N . VAL A 1 454 ? -37.397 -7.442 38.253 1.00 16.68 ? 474 VAL A N 1 ATOM 3460 C CA . VAL A 1 454 ? -36.572 -8.284 39.101 1.00 16.41 ? 474 VAL A CA 1 ATOM 3461 C C . VAL A 1 454 ? -36.753 -7.831 40.556 1.00 16.99 ? 474 VAL A C 1 ATOM 3462 O O . VAL A 1 454 ? -36.720 -6.636 40.847 1.00 16.79 ? 474 VAL A O 1 ATOM 3463 C CB . VAL A 1 454 ? -35.084 -8.187 38.679 1.00 16.00 ? 474 VAL A CB 1 ATOM 3464 C CG1 . VAL A 1 454 ? -34.153 -8.924 39.674 1.00 15.19 ? 474 VAL A CG1 1 ATOM 3465 C CG2 . VAL A 1 454 ? -34.923 -8.738 37.273 1.00 15.92 ? 474 VAL A CG2 1 ATOM 3466 N N A MET A 1 455 ? -36.952 -8.775 41.465 0.50 17.31 ? 475 MET A N 1 ATOM 3467 N N B MET A 1 455 ? -36.977 -8.800 41.448 0.50 17.15 ? 475 MET A N 1 ATOM 3468 C CA A MET A 1 455 ? -36.883 -8.441 42.877 0.50 17.76 ? 475 MET A CA 1 ATOM 3469 C CA B MET A 1 455 ? -37.002 -8.573 42.899 0.50 17.46 ? 475 MET A CA 1 ATOM 3470 C C A MET A 1 455 ? -35.898 -9.351 43.576 0.50 17.60 ? 475 MET A C 1 ATOM 3471 C C B MET A 1 455 ? -35.805 -9.306 43.501 0.50 17.43 ? 475 MET A C 1 ATOM 3472 O O A MET A 1 455 ? -35.680 -10.484 43.173 0.50 17.71 ? 475 MET A O 1 ATOM 3473 O O B MET A 1 455 ? -35.314 -10.268 42.924 0.50 17.45 ? 475 MET A O 1 ATOM 3474 C CB A MET A 1 455 ? -38.248 -8.487 43.555 0.50 17.92 ? 475 MET A CB 1 ATOM 3475 C CB B MET A 1 455 ? -38.305 -9.093 43.527 0.50 17.53 ? 475 MET A CB 1 ATOM 3476 C CG A MET A 1 455 ? -38.899 -9.835 43.582 0.50 18.98 ? 475 MET A CG 1 ATOM 3477 C CG B MET A 1 455 ? -38.428 -8.843 45.037 0.50 17.84 ? 475 MET A CG 1 ATOM 3478 S SD A MET A 1 455 ? -40.184 -9.834 44.834 0.50 21.03 ? 475 MET A SD 1 ATOM 3479 S SD B MET A 1 455 ? -39.896 -9.562 45.813 0.50 19.85 ? 475 MET A SD 1 ATOM 3480 C CE A MET A 1 455 ? -39.199 -10.000 46.325 0.50 20.70 ? 475 MET A CE 1 ATOM 3481 C CE B MET A 1 455 ? -39.506 -9.420 47.550 0.50 19.07 ? 475 MET A CE 1 ATOM 3482 N N . GLU A 1 456 ? -35.315 -8.829 44.637 1.00 17.55 ? 476 GLU A N 1 ATOM 3483 C CA . GLU A 1 456 ? -34.202 -9.466 45.299 1.00 17.68 ? 476 GLU A CA 1 ATOM 3484 C C . GLU A 1 456 ? -34.420 -9.367 46.783 1.00 17.53 ? 476 GLU A C 1 ATOM 3485 O O . GLU A 1 456 ? -34.871 -8.337 47.267 1.00 17.61 ? 476 GLU A O 1 ATOM 3486 C CB . GLU A 1 456 ? -32.915 -8.755 44.893 1.00 17.74 ? 476 GLU A CB 1 ATOM 3487 C CG . GLU A 1 456 ? -31.708 -9.135 45.712 1.00 18.83 ? 476 GLU A CG 1 ATOM 3488 C CD . GLU A 1 456 ? -30.427 -8.674 45.076 1.00 19.45 ? 476 GLU A CD 1 ATOM 3489 O OE1 . GLU A 1 456 ? -30.465 -7.781 44.197 1.00 19.81 ? 476 GLU A OE1 1 ATOM 3490 O OE2 . GLU A 1 456 ? -29.373 -9.208 45.465 1.00 22.75 ? 476 GLU A OE2 1 ATOM 3491 N N . ALA A 1 457 ? -34.135 -10.455 47.491 1.00 17.58 ? 477 ALA A N 1 ATOM 3492 C CA . ALA A 1 457 ? -34.119 -10.471 48.935 1.00 17.74 ? 477 ALA A CA 1 ATOM 3493 C C . ALA A 1 457 ? -32.670 -10.587 49.366 1.00 18.48 ? 477 ALA A C 1 ATOM 3494 O O . ALA A 1 457 ? -31.883 -11.288 48.737 1.00 17.64 ? 477 ALA A O 1 ATOM 3495 C CB . ALA A 1 457 ? -34.915 -11.633 49.462 1.00 17.75 ? 477 ALA A CB 1 ATOM 3496 N N . LYS A 1 458 ? -32.327 -9.902 50.454 1.00 19.32 ? 478 LYS A N 1 ATOM 3497 C CA . LYS A 1 458 ? -30.954 -9.835 50.911 1.00 19.78 ? 478 LYS A CA 1 ATOM 3498 C C . LYS A 1 458 ? -30.927 -9.708 52.437 1.00 19.70 ? 478 LYS A C 1 ATOM 3499 O O . LYS A 1 458 ? -31.751 -9.002 53.041 1.00 19.32 ? 478 LYS A O 1 ATOM 3500 C CB . LYS A 1 458 ? -30.282 -8.627 50.246 1.00 20.42 ? 478 LYS A CB 1 ATOM 3501 C CG . LYS A 1 458 ? -28.766 -8.700 50.174 1.00 22.62 ? 478 LYS A CG 1 ATOM 3502 C CD . LYS A 1 458 ? -28.155 -7.418 49.571 1.00 23.40 ? 478 LYS A CD 1 ATOM 3503 C CE . LYS A 1 458 ? -28.399 -7.308 48.091 1.00 25.21 ? 478 LYS A CE 1 ATOM 3504 N NZ . LYS A 1 458 ? -27.755 -6.105 47.475 1.00 25.69 ? 478 LYS A NZ 1 ATOM 3505 N N . MET A 1 459 ? -30.017 -10.435 53.065 1.00 19.69 ? 479 MET A N 1 ATOM 3506 C CA . MET A 1 459 ? -29.668 -10.195 54.452 1.00 19.93 ? 479 MET A CA 1 ATOM 3507 C C . MET A 1 459 ? -28.187 -9.805 54.493 1.00 19.99 ? 479 MET A C 1 ATOM 3508 O O . MET A 1 459 ? -27.375 -10.394 53.789 1.00 19.47 ? 479 MET A O 1 ATOM 3509 C CB . MET A 1 459 ? -29.944 -11.450 55.278 1.00 20.35 ? 479 MET A CB 1 ATOM 3510 C CG . MET A 1 459 ? -29.636 -11.352 56.766 1.00 21.68 ? 479 MET A CG 1 ATOM 3511 S SD . MET A 1 459 ? -27.898 -11.685 57.204 1.00 26.24 ? 479 MET A SD 1 ATOM 3512 C CE . MET A 1 459 ? -27.549 -13.262 56.434 1.00 26.74 ? 479 MET A CE 1 ATOM 3513 N N . HIS A 1 460 ? -27.847 -8.796 55.291 1.00 20.20 ? 480 HIS A N 1 ATOM 3514 C CA . HIS A 1 460 ? -26.444 -8.481 55.581 1.00 20.54 ? 480 HIS A CA 1 ATOM 3515 C C . HIS A 1 460 ? -26.200 -8.684 57.065 1.00 20.32 ? 480 HIS A C 1 ATOM 3516 O O . HIS A 1 460 ? -27.069 -8.368 57.872 1.00 21.57 ? 480 HIS A O 1 ATOM 3517 C CB . HIS A 1 460 ? -26.093 -7.020 55.267 1.00 20.43 ? 480 HIS A CB 1 ATOM 3518 C CG . HIS A 1 460 ? -26.688 -6.482 54.007 1.00 21.54 ? 480 HIS A CG 1 ATOM 3519 N ND1 . HIS A 1 460 ? -25.938 -6.258 52.871 1.00 21.27 ? 480 HIS A ND1 1 ATOM 3520 C CD2 . HIS A 1 460 ? -27.941 -6.052 53.726 1.00 21.53 ? 480 HIS A CD2 1 ATOM 3521 C CE1 . HIS A 1 460 ? -26.716 -5.747 51.934 1.00 23.37 ? 480 HIS A CE1 1 ATOM 3522 N NE2 . HIS A 1 460 ? -27.936 -5.606 52.429 1.00 22.63 ? 480 HIS A NE2 1 ATOM 3523 N N . ALA A 1 461 ? -25.016 -9.158 57.430 1.00 19.90 ? 481 ALA A N 1 ATOM 3524 C CA . ALA A 1 461 ? -24.636 -9.295 58.837 1.00 20.03 ? 481 ALA A CA 1 ATOM 3525 C C . ALA A 1 461 ? -23.626 -8.230 59.264 1.00 19.95 ? 481 ALA A C 1 ATOM 3526 O O . ALA A 1 461 ? -22.629 -7.995 58.571 1.00 19.90 ? 481 ALA A O 1 ATOM 3527 C CB . ALA A 1 461 ? -24.063 -10.669 59.095 1.00 19.91 ? 481 ALA A CB 1 ATOM 3528 N N . THR A 1 462 ? -23.892 -7.594 60.405 1.00 19.75 ? 482 THR A N 1 ATOM 3529 C CA . THR A 1 462 ? -22.918 -6.732 61.061 1.00 19.73 ? 482 THR A CA 1 ATOM 3530 C C . THR A 1 462 ? -23.126 -6.756 62.599 1.00 20.48 ? 482 THR A C 1 ATOM 3531 O O . THR A 1 462 ? -23.819 -7.621 63.106 1.00 20.12 ? 482 THR A O 1 ATOM 3532 C CB . THR A 1 462 ? -22.934 -5.305 60.440 1.00 19.76 ? 482 THR A CB 1 ATOM 3533 O OG1 . THR A 1 462 ? -21.899 -4.514 61.029 1.00 18.99 ? 482 THR A OG1 1 ATOM 3534 C CG2 . THR A 1 462 ? -24.295 -4.625 60.615 1.00 19.06 ? 482 THR A CG2 1 ATOM 3535 N N . GLY A 1 463 ? -22.519 -5.842 63.355 1.00 20.77 ? 483 GLY A N 1 ATOM 3536 C CA . GLY A 1 463 ? -22.631 -5.917 64.814 1.00 21.01 ? 483 GLY A CA 1 ATOM 3537 C C . GLY A 1 463 ? -21.543 -6.798 65.396 1.00 20.91 ? 483 GLY A C 1 ATOM 3538 O O . GLY A 1 463 ? -20.543 -7.071 64.725 1.00 21.35 ? 483 GLY A O 1 ATOM 3539 N N . TYR A 1 464 ? -21.739 -7.255 66.631 1.00 20.83 ? 484 TYR A N 1 ATOM 3540 C CA . TYR A 1 464 ? -20.707 -8.009 67.369 1.00 20.98 ? 484 TYR A CA 1 ATOM 3541 C C . TYR A 1 464 ? -20.852 -9.519 67.212 1.00 20.94 ? 484 TYR A C 1 ATOM 3542 O O . TYR A 1 464 ? -21.967 -10.038 67.284 1.00 20.43 ? 484 TYR A O 1 ATOM 3543 C CB . TYR A 1 464 ? -20.794 -7.698 68.868 1.00 21.01 ? 484 TYR A CB 1 ATOM 3544 C CG . TYR A 1 464 ? -20.367 -6.304 69.240 1.00 20.74 ? 484 TYR A CG 1 ATOM 3545 C CD1 . TYR A 1 464 ? -21.294 -5.269 69.295 1.00 19.97 ? 484 TYR A CD1 1 ATOM 3546 C CD2 . TYR A 1 464 ? -19.030 -6.021 69.541 1.00 19.56 ? 484 TYR A CD2 1 ATOM 3547 C CE1 . TYR A 1 464 ? -20.906 -3.976 69.629 1.00 21.44 ? 484 TYR A CE1 1 ATOM 3548 C CE2 . TYR A 1 464 ? -18.634 -4.739 69.877 1.00 20.69 ? 484 TYR A CE2 1 ATOM 3549 C CZ . TYR A 1 464 ? -19.576 -3.721 69.926 1.00 20.70 ? 484 TYR A CZ 1 ATOM 3550 O OH . TYR A 1 464 ? -19.203 -2.451 70.262 1.00 21.98 ? 484 TYR A OH 1 ATOM 3551 N N . VAL A 1 465 ? -19.726 -10.220 67.046 1.00 20.75 ? 485 VAL A N 1 ATOM 3552 C CA . VAL A 1 465 ? -19.727 -11.695 67.027 1.00 20.77 ? 485 VAL A CA 1 ATOM 3553 C C . VAL A 1 465 ? -20.039 -12.283 68.413 1.00 21.71 ? 485 VAL A C 1 ATOM 3554 O O . VAL A 1 465 ? -19.852 -11.628 69.438 1.00 21.77 ? 485 VAL A O 1 ATOM 3555 C CB . VAL A 1 465 ? -18.370 -12.303 66.524 1.00 20.77 ? 485 VAL A CB 1 ATOM 3556 C CG1 . VAL A 1 465 ? -18.029 -11.799 65.124 1.00 19.90 ? 485 VAL A CG1 1 ATOM 3557 C CG2 . VAL A 1 465 ? -17.225 -12.022 67.495 1.00 19.34 ? 485 VAL A CG2 1 ATOM 3558 N N . HIS A 1 466 ? -20.541 -13.515 68.413 1.00 22.41 ? 486 HIS A N 1 ATOM 3559 C CA . HIS A 1 466 ? -20.728 -14.324 69.614 1.00 22.90 ? 486 HIS A CA 1 ATOM 3560 C C . HIS A 1 466 ? -19.373 -14.953 69.944 1.00 23.43 ? 486 HIS A C 1 ATOM 3561 O O . HIS A 1 466 ? -18.817 -15.700 69.131 1.00 23.71 ? 486 HIS A O 1 ATOM 3562 C CB . HIS A 1 466 ? -21.773 -15.404 69.324 1.00 22.86 ? 486 HIS A CB 1 ATOM 3563 C CG . HIS A 1 466 ? -22.148 -16.245 70.501 1.00 22.39 ? 486 HIS A CG 1 ATOM 3564 N ND1 . HIS A 1 466 ? -22.630 -15.715 71.677 1.00 22.39 ? 486 HIS A ND1 1 ATOM 3565 C CD2 . HIS A 1 466 ? -22.159 -17.590 70.662 1.00 22.56 ? 486 HIS A CD2 1 ATOM 3566 C CE1 . HIS A 1 466 ? -22.906 -16.695 72.519 1.00 22.46 ? 486 HIS A CE1 1 ATOM 3567 N NE2 . HIS A 1 466 ? -22.631 -17.844 71.926 1.00 21.73 ? 486 HIS A NE2 1 ATOM 3568 N N . ALA A 1 467 ? -18.846 -14.651 71.130 1.00 23.82 ? 487 ALA A N 1 ATOM 3569 C CA . ALA A 1 467 ? -17.444 -14.933 71.445 1.00 23.88 ? 487 ALA A CA 1 ATOM 3570 C C . ALA A 1 467 ? -17.294 -15.493 72.851 1.00 24.11 ? 487 ALA A C 1 ATOM 3571 O O . ALA A 1 467 ? -18.090 -15.183 73.734 1.00 23.69 ? 487 ALA A O 1 ATOM 3572 C CB . ALA A 1 467 ? -16.620 -13.662 71.297 1.00 23.46 ? 487 ALA A CB 1 ATOM 3573 N N . THR A 1 468 ? -16.251 -16.299 73.047 1.00 24.51 ? 488 THR A N 1 ATOM 3574 C CA . THR A 1 468 ? -15.984 -16.951 74.336 1.00 24.52 ? 488 THR A CA 1 ATOM 3575 C C . THR A 1 468 ? -14.539 -16.722 74.787 1.00 24.83 ? 488 THR A C 1 ATOM 3576 O O . THR A 1 468 ? -13.714 -16.169 74.041 1.00 24.16 ? 488 THR A O 1 ATOM 3577 C CB . THR A 1 468 ? -16.307 -18.470 74.283 1.00 24.75 ? 488 THR A CB 1 ATOM 3578 O OG1 . THR A 1 468 ? -15.630 -19.086 73.178 1.00 24.05 ? 488 THR A OG1 1 ATOM 3579 C CG2 . THR A 1 468 ? -17.830 -18.699 74.151 1.00 24.02 ? 488 THR A CG2 1 ATOM 3580 N N . PHE A 1 469 ? -14.249 -17.137 76.018 1.00 25.27 ? 489 PHE A N 1 ATOM 3581 C CA . PHE A 1 469 ? -12.936 -16.919 76.626 1.00 25.67 ? 489 PHE A CA 1 ATOM 3582 C C . PHE A 1 469 ? -11.889 -17.756 75.936 1.00 26.00 ? 489 PHE A C 1 ATOM 3583 O O . PHE A 1 469 ? -12.103 -18.942 75.716 1.00 25.92 ? 489 PHE A O 1 ATOM 3584 C CB . PHE A 1 469 ? -12.968 -17.299 78.105 1.00 25.64 ? 489 PHE A CB 1 ATOM 3585 C CG . PHE A 1 469 ? -11.719 -16.928 78.864 1.00 25.98 ? 489 PHE A CG 1 ATOM 3586 C CD1 . PHE A 1 469 ? -11.413 -15.591 79.113 1.00 26.47 ? 489 PHE A CD1 1 ATOM 3587 C CD2 . PHE A 1 469 ? -10.877 -17.912 79.379 1.00 26.01 ? 489 PHE A CD2 1 ATOM 3588 C CE1 . PHE A 1 469 ? -10.274 -15.244 79.834 1.00 26.30 ? 489 PHE A CE1 1 ATOM 3589 C CE2 . PHE A 1 469 ? -9.734 -17.563 80.112 1.00 25.35 ? 489 PHE A CE2 1 ATOM 3590 C CZ . PHE A 1 469 ? -9.434 -16.240 80.332 1.00 25.14 ? 489 PHE A CZ 1 ATOM 3591 N N . TYR A 1 470 ? -10.756 -17.139 75.614 1.00 26.87 ? 490 TYR A N 1 ATOM 3592 C CA . TYR A 1 470 ? -9.656 -17.847 74.945 1.00 27.66 ? 490 TYR A CA 1 ATOM 3593 C C . TYR A 1 470 ? -8.981 -18.859 75.859 1.00 28.09 ? 490 TYR A C 1 ATOM 3594 O O . TYR A 1 470 ? -8.597 -18.543 76.977 1.00 28.24 ? 490 TYR A O 1 ATOM 3595 C CB . TYR A 1 470 ? -8.587 -16.882 74.416 1.00 27.38 ? 490 TYR A CB 1 ATOM 3596 C CG . TYR A 1 470 ? -7.321 -17.599 74.004 1.00 28.53 ? 490 TYR A CG 1 ATOM 3597 C CD1 . TYR A 1 470 ? -6.211 -17.648 74.852 1.00 29.64 ? 490 TYR A CD1 1 ATOM 3598 C CD2 . TYR A 1 470 ? -7.246 -18.272 72.787 1.00 29.21 ? 490 TYR A CD2 1 ATOM 3599 C CE1 . TYR A 1 470 ? -5.062 -18.331 74.487 1.00 29.74 ? 490 TYR A CE1 1 ATOM 3600 C CE2 . TYR A 1 470 ? -6.102 -18.948 72.410 1.00 29.39 ? 490 TYR A CE2 1 ATOM 3601 C CZ . TYR A 1 470 ? -5.013 -18.979 73.264 1.00 30.15 ? 490 TYR A CZ 1 ATOM 3602 O OH . TYR A 1 470 ? -3.874 -19.648 72.881 1.00 30.53 ? 490 TYR A OH 1 ATOM 3603 N N . THR A 1 471 ? -8.872 -20.084 75.364 1.00 29.15 ? 491 THR A N 1 ATOM 3604 C CA . THR A 1 471 ? -7.881 -21.047 75.832 1.00 29.77 ? 491 THR A CA 1 ATOM 3605 C C . THR A 1 471 ? -7.348 -21.691 74.557 1.00 30.49 ? 491 THR A C 1 ATOM 3606 O O . THR A 1 471 ? -8.022 -21.613 73.527 1.00 30.49 ? 491 THR A O 1 ATOM 3607 C CB . THR A 1 471 ? -8.489 -22.147 76.694 1.00 29.85 ? 491 THR A CB 1 ATOM 3608 O OG1 . THR A 1 471 ? -9.146 -23.093 75.843 1.00 29.51 ? 491 THR A OG1 1 ATOM 3609 C CG2 . THR A 1 471 ? -9.485 -21.579 77.715 1.00 29.02 ? 491 THR A CG2 1 ATOM 3610 N N . PRO A 1 472 ? -6.160 -22.337 74.617 1.00 31.04 ? 492 PRO A N 1 ATOM 3611 C CA . PRO A 1 472 ? -5.571 -22.992 73.441 1.00 31.40 ? 492 PRO A CA 1 ATOM 3612 C C . PRO A 1 472 ? -6.497 -23.989 72.741 1.00 31.77 ? 492 PRO A C 1 ATOM 3613 O O . PRO A 1 472 ? -6.507 -24.060 71.516 1.00 31.97 ? 492 PRO A O 1 ATOM 3614 C CB . PRO A 1 472 ? -4.343 -23.700 74.016 1.00 31.53 ? 492 PRO A CB 1 ATOM 3615 C CG . PRO A 1 472 ? -3.929 -22.835 75.162 1.00 31.13 ? 492 PRO A CG 1 ATOM 3616 C CD . PRO A 1 472 ? -5.235 -22.356 75.767 1.00 31.18 ? 492 PRO A CD 1 ATOM 3617 N N . GLU A 1 473 ? -7.283 -24.725 73.522 1.00 32.12 ? 493 GLU A N 1 ATOM 3618 C CA . GLU A 1 473 ? -8.268 -25.675 72.995 1.00 32.27 ? 493 GLU A CA 1 ATOM 3619 C C . GLU A 1 473 ? -9.357 -25.005 72.150 1.00 31.55 ? 493 GLU A C 1 ATOM 3620 O O . GLU A 1 473 ? -10.005 -25.660 71.335 1.00 31.58 ? 493 GLU A O 1 ATOM 3621 C CB . GLU A 1 473 ? -8.933 -26.450 74.145 1.00 32.86 ? 493 GLU A CB 1 ATOM 3622 C CG . GLU A 1 473 ? -8.067 -27.548 74.778 1.00 34.94 ? 493 GLU A CG 1 ATOM 3623 C CD . GLU A 1 473 ? -7.055 -27.038 75.797 1.00 38.58 ? 493 GLU A CD 1 ATOM 3624 O OE1 . GLU A 1 473 ? -7.297 -25.985 76.434 1.00 40.27 ? 493 GLU A OE1 1 ATOM 3625 O OE2 . GLU A 1 473 ? -6.012 -27.712 75.976 1.00 40.83 ? 493 GLU A OE2 1 ATOM 3626 N N . GLY A 1 474 ? -9.569 -23.708 72.360 1.00 30.89 ? 494 GLY A N 1 ATOM 3627 C CA . GLY A 1 474 ? -10.525 -22.933 71.572 1.00 30.06 ? 494 GLY A CA 1 ATOM 3628 C C . GLY A 1 474 ? -10.198 -22.819 70.098 1.00 29.44 ? 494 GLY A C 1 ATOM 3629 O O . GLY A 1 474 ? -11.099 -22.628 69.274 1.00 28.95 ? 494 GLY A O 1 ATOM 3630 N N . LEU A 1 475 ? -8.918 -22.956 69.757 1.00 28.55 ? 495 LEU A N 1 ATOM 3631 C CA . LEU A 1 475 ? -8.480 -22.829 68.365 1.00 27.87 ? 495 LEU A CA 1 ATOM 3632 C C . LEU A 1 475 ? -9.014 -23.939 67.444 1.00 27.28 ? 495 LEU A C 1 ATOM 3633 O O . LEU A 1 475 ? -9.029 -23.778 66.230 1.00 27.72 ? 495 LEU A O 1 ATOM 3634 C CB . LEU A 1 475 ? -6.951 -22.722 68.298 1.00 27.80 ? 495 LEU A CB 1 ATOM 3635 C CG . LEU A 1 475 ? -6.357 -21.520 69.049 1.00 27.82 ? 495 LEU A CG 1 ATOM 3636 C CD1 . LEU A 1 475 ? -4.852 -21.440 68.854 1.00 28.09 ? 495 LEU A CD1 1 ATOM 3637 C CD2 . LEU A 1 475 ? -7.007 -20.217 68.601 1.00 28.35 ? 495 LEU A CD2 1 ATOM 3638 N N . ARG A 1 476 ? -9.484 -25.045 68.009 1.00 26.64 ? 496 ARG A N 1 ATOM 3639 C CA . ARG A 1 476 ? -10.161 -26.071 67.221 1.00 26.70 ? 496 ARG A CA 1 ATOM 3640 C C . ARG A 1 476 ? -11.623 -25.710 66.872 1.00 25.94 ? 496 ARG A C 1 ATOM 3641 O O . ARG A 1 476 ? -12.274 -26.437 66.133 1.00 25.11 ? 496 ARG A O 1 ATOM 3642 C CB . ARG A 1 476 ? -10.153 -27.410 67.957 1.00 27.05 ? 496 ARG A CB 1 ATOM 3643 C CG . ARG A 1 476 ? -8.762 -28.023 68.132 1.00 29.22 ? 496 ARG A CG 1 ATOM 3644 C CD . ARG A 1 476 ? -8.810 -29.452 68.708 1.00 31.31 ? 496 ARG A CD 1 ATOM 3645 N NE . ARG A 1 476 ? -9.673 -30.341 67.919 1.00 33.11 ? 496 ARG A NE 1 ATOM 3646 C CZ . ARG A 1 476 ? -10.869 -30.800 68.297 1.00 33.92 ? 496 ARG A CZ 1 ATOM 3647 N NH1 . ARG A 1 476 ? -11.383 -30.494 69.482 1.00 34.80 ? 496 ARG A NH1 1 ATOM 3648 N NH2 . ARG A 1 476 ? -11.558 -31.589 67.480 1.00 34.20 ? 496 ARG A NH2 1 ATOM 3649 N N . HIS A 1 477 ? -12.134 -24.612 67.420 1.00 25.26 ? 497 HIS A N 1 ATOM 3650 C CA . HIS A 1 477 ? -13.531 -24.236 67.233 1.00 25.04 ? 497 HIS A CA 1 ATOM 3651 C C . HIS A 1 477 ? -13.709 -22.749 66.925 1.00 24.88 ? 497 HIS A C 1 ATOM 3652 O O . HIS A 1 477 ? -14.800 -22.201 67.117 1.00 24.58 ? 497 HIS A O 1 ATOM 3653 C CB . HIS A 1 477 ? -14.329 -24.591 68.480 1.00 24.90 ? 497 HIS A CB 1 ATOM 3654 C CG . HIS A 1 477 ? -14.201 -26.022 68.893 1.00 25.17 ? 497 HIS A CG 1 ATOM 3655 N ND1 . HIS A 1 477 ? -14.994 -27.021 68.369 1.00 24.88 ? 497 HIS A ND1 1 ATOM 3656 C CD2 . HIS A 1 477 ? -13.385 -26.622 69.792 1.00 24.80 ? 497 HIS A CD2 1 ATOM 3657 C CE1 . HIS A 1 477 ? -14.672 -28.172 68.927 1.00 24.26 ? 497 HIS A CE1 1 ATOM 3658 N NE2 . HIS A 1 477 ? -13.692 -27.961 69.786 1.00 23.80 ? 497 HIS A NE2 1 ATOM 3659 N N . GLY A 1 478 ? -12.651 -22.109 66.431 1.00 24.69 ? 498 GLY A N 1 ATOM 3660 C CA . GLY A 1 478 ? -12.656 -20.666 66.224 1.00 25.04 ? 498 GLY A CA 1 ATOM 3661 C C . GLY A 1 478 ? -11.271 -20.021 66.168 1.00 25.10 ? 498 GLY A C 1 ATOM 3662 O O . GLY A 1 478 ? -10.255 -20.697 66.012 1.00 24.78 ? 498 GLY A O 1 ATOM 3663 N N . THR A 1 479 ? -11.258 -18.697 66.304 1.00 25.30 ? 499 THR A N 1 ATOM 3664 C CA . THR A 1 479 ? -10.080 -17.883 66.062 1.00 25.21 ? 499 THR A CA 1 ATOM 3665 C C . THR A 1 479 ? -9.850 -16.923 67.213 1.00 25.43 ? 499 THR A C 1 ATOM 3666 O O . THR A 1 479 ? -10.793 -16.290 67.688 1.00 25.28 ? 499 THR A O 1 ATOM 3667 C CB . THR A 1 479 ? -10.269 -17.040 64.782 1.00 25.18 ? 499 THR A CB 1 ATOM 3668 O OG1 . THR A 1 479 ? -10.618 -17.899 63.692 1.00 24.50 ? 499 THR A OG1 1 ATOM 3669 C CG2 . THR A 1 479 ? -8.998 -16.253 64.443 1.00 24.02 ? 499 THR A CG2 1 ATOM 3670 N N . ARG A 1 480 ? -8.596 -16.817 67.650 1.00 25.58 ? 500 ARG A N 1 ATOM 3671 C CA . ARG A 1 480 ? -8.197 -15.812 68.638 1.00 25.58 ? 500 ARG A CA 1 ATOM 3672 C C . ARG A 1 480 ? -8.236 -14.428 68.015 1.00 25.18 ? 500 ARG A C 1 ATOM 3673 O O . ARG A 1 480 ? -7.540 -14.165 67.025 1.00 24.53 ? 500 ARG A O 1 ATOM 3674 C CB . ARG A 1 480 ? -6.790 -16.095 69.172 1.00 25.91 ? 500 ARG A CB 1 ATOM 3675 C CG . ARG A 1 480 ? -6.456 -15.299 70.418 1.00 27.17 ? 500 ARG A CG 1 ATOM 3676 C CD . ARG A 1 480 ? -5.067 -15.620 70.919 1.00 27.78 ? 500 ARG A CD 1 ATOM 3677 N NE . ARG A 1 480 ? -4.823 -15.042 72.230 1.00 29.40 ? 500 ARG A NE 1 ATOM 3678 C CZ . ARG A 1 480 ? -3.746 -15.286 72.982 1.00 30.59 ? 500 ARG A CZ 1 ATOM 3679 N NH1 . ARG A 1 480 ? -2.786 -16.103 72.564 1.00 29.71 ? 500 ARG A NH1 1 ATOM 3680 N NH2 . ARG A 1 480 ? -3.632 -14.703 74.166 1.00 30.52 ? 500 ARG A NH2 1 ATOM 3681 N N . LEU A 1 481 ? -9.047 -13.545 68.599 1.00 24.89 ? 501 LEU A N 1 ATOM 3682 C CA . LEU A 1 481 ? -9.276 -12.202 68.046 1.00 24.98 ? 501 LEU A CA 1 ATOM 3683 C C . LEU A 1 481 ? -8.686 -11.096 68.895 1.00 25.22 ? 501 LEU A C 1 ATOM 3684 O O . LEU A 1 481 ? -8.480 -9.963 68.423 1.00 25.48 ? 501 LEU A O 1 ATOM 3685 C CB . LEU A 1 481 ? -10.775 -11.959 67.908 1.00 24.87 ? 501 LEU A CB 1 ATOM 3686 C CG . LEU A 1 481 ? -11.535 -13.025 67.123 1.00 24.60 ? 501 LEU A CG 1 ATOM 3687 C CD1 . LEU A 1 481 ? -13.021 -12.688 67.078 1.00 24.40 ? 501 LEU A CD1 1 ATOM 3688 C CD2 . LEU A 1 481 ? -10.946 -13.151 65.721 1.00 25.03 ? 501 LEU A CD2 1 ATOM 3689 N N . HIS A 1 482 ? -8.456 -11.417 70.163 1.00 25.53 ? 502 HIS A N 1 ATOM 3690 C CA . HIS A 1 482 ? -7.825 -10.509 71.108 1.00 25.56 ? 502 HIS A CA 1 ATOM 3691 C C . HIS A 1 482 ? -7.182 -11.367 72.191 1.00 25.39 ? 502 HIS A C 1 ATOM 3692 O O . HIS A 1 482 ? -7.213 -12.594 72.096 1.00 24.82 ? 502 HIS A O 1 ATOM 3693 C CB . HIS A 1 482 ? -8.851 -9.532 71.696 1.00 25.61 ? 502 HIS A CB 1 ATOM 3694 C CG . HIS A 1 482 ? -8.264 -8.204 72.061 1.00 26.82 ? 502 HIS A CG 1 ATOM 3695 N ND1 . HIS A 1 482 ? -7.794 -7.919 73.329 1.00 25.71 ? 502 HIS A ND1 1 ATOM 3696 C CD2 . HIS A 1 482 ? -8.039 -7.094 71.316 1.00 26.46 ? 502 HIS A CD2 1 ATOM 3697 C CE1 . HIS A 1 482 ? -7.326 -6.683 73.351 1.00 25.32 ? 502 HIS A CE1 1 ATOM 3698 N NE2 . HIS A 1 482 ? -7.467 -6.159 72.145 1.00 26.28 ? 502 HIS A NE2 1 ATOM 3699 N N . THR A 1 483 ? -6.594 -10.723 73.201 1.00 25.75 ? 503 THR A N 1 ATOM 3700 C CA . THR A 1 483 ? -5.796 -11.412 74.221 1.00 25.74 ? 503 THR A CA 1 ATOM 3701 C C . THR A 1 483 ? -6.572 -12.557 74.860 1.00 25.59 ? 503 THR A C 1 ATOM 3702 O O . THR A 1 483 ? -6.090 -13.683 74.887 1.00 25.91 ? 503 THR A O 1 ATOM 3703 C CB . THR A 1 483 ? -5.293 -10.431 75.320 1.00 26.06 ? 503 THR A CB 1 ATOM 3704 O OG1 . THR A 1 483 ? -4.669 -9.298 74.707 1.00 27.30 ? 503 THR A OG1 1 ATOM 3705 C CG2 . THR A 1 483 ? -4.281 -11.106 76.253 1.00 25.01 ? 503 THR A CG2 1 ATOM 3706 N N . HIS A 1 484 ? -7.787 -12.280 75.317 1.00 25.72 ? 504 HIS A N 1 ATOM 3707 C CA . HIS A 1 484 ? -8.607 -13.274 76.022 1.00 25.79 ? 504 HIS A CA 1 ATOM 3708 C C . HIS A 1 484 ? -9.857 -13.713 75.252 1.00 25.04 ? 504 HIS A C 1 ATOM 3709 O O . HIS A 1 484 ? -10.791 -14.256 75.848 1.00 24.56 ? 504 HIS A O 1 ATOM 3710 C CB . HIS A 1 484 ? -9.043 -12.709 77.390 1.00 26.41 ? 504 HIS A CB 1 ATOM 3711 C CG . HIS A 1 484 ? -7.909 -12.231 78.246 1.00 27.96 ? 504 HIS A CG 1 ATOM 3712 N ND1 . HIS A 1 484 ? -6.973 -13.086 78.792 1.00 30.67 ? 504 HIS A ND1 1 ATOM 3713 C CD2 . HIS A 1 484 ? -7.566 -10.986 78.658 1.00 29.30 ? 504 HIS A CD2 1 ATOM 3714 C CE1 . HIS A 1 484 ? -6.103 -12.388 79.503 1.00 29.89 ? 504 HIS A CE1 1 ATOM 3715 N NE2 . HIS A 1 484 ? -6.444 -11.112 79.440 1.00 29.23 ? 504 HIS A NE2 1 ATOM 3716 N N . LEU A 1 485 ? -9.869 -13.519 73.934 1.00 24.44 ? 505 LEU A N 1 ATOM 3717 C CA . LEU A 1 485 ? -11.107 -13.645 73.155 1.00 24.01 ? 505 LEU A CA 1 ATOM 3718 C C . LEU A 1 485 ? -10.999 -14.649 72.005 1.00 23.91 ? 505 LEU A C 1 ATOM 3719 O O . LEU A 1 485 ? -10.073 -14.578 71.199 1.00 22.97 ? 505 LEU A O 1 ATOM 3720 C CB . LEU A 1 485 ? -11.475 -12.278 72.585 1.00 23.78 ? 505 LEU A CB 1 ATOM 3721 C CG . LEU A 1 485 ? -12.869 -12.119 71.969 1.00 24.09 ? 505 LEU A CG 1 ATOM 3722 C CD1 . LEU A 1 485 ? -13.983 -12.352 73.010 1.00 22.57 ? 505 LEU A CD1 1 ATOM 3723 C CD2 . LEU A 1 485 ? -12.980 -10.733 71.328 1.00 22.31 ? 505 LEU A CD2 1 ATOM 3724 N N . ILE A 1 486 ? -11.963 -15.569 71.935 1.00 23.72 ? 506 ILE A N 1 ATOM 3725 C CA . ILE A 1 486 ? -12.114 -16.472 70.780 1.00 23.54 ? 506 ILE A CA 1 ATOM 3726 C C . ILE A 1 486 ? -13.413 -16.151 70.069 1.00 23.09 ? 506 ILE A C 1 ATOM 3727 O O . ILE A 1 486 ? -14.471 -16.054 70.702 1.00 23.11 ? 506 ILE A O 1 ATOM 3728 C CB . ILE A 1 486 ? -12.160 -17.965 71.181 1.00 23.65 ? 506 ILE A CB 1 ATOM 3729 C CG1 . ILE A 1 486 ? -10.757 -18.484 71.506 1.00 24.59 ? 506 ILE A CG1 1 ATOM 3730 C CG2 . ILE A 1 486 ? -12.749 -18.815 70.058 1.00 23.92 ? 506 ILE A CG2 1 ATOM 3731 C CD1 . ILE A 1 486 ? -10.021 -19.042 70.335 1.00 25.12 ? 506 ILE A CD1 1 ATOM 3732 N N . GLY A 1 487 ? -13.326 -15.961 68.760 1.00 22.36 ? 507 GLY A N 1 ATOM 3733 C CA . GLY A 1 487 ? -14.513 -15.905 67.925 1.00 21.93 ? 507 GLY A CA 1 ATOM 3734 C C . GLY A 1 487 ? -14.861 -17.308 67.485 1.00 21.30 ? 507 GLY A C 1 ATOM 3735 O O . GLY A 1 487 ? -14.154 -17.894 66.672 1.00 21.70 ? 507 GLY A O 1 ATOM 3736 N N . ASN A 1 488 ? -15.947 -17.846 68.024 1.00 20.76 ? 508 ASN A N 1 ATOM 3737 C CA . ASN A 1 488 ? -16.394 -19.204 67.709 1.00 20.34 ? 508 ASN A CA 1 ATOM 3738 C C . ASN A 1 488 ? -16.829 -19.367 66.265 1.00 20.54 ? 508 ASN A C 1 ATOM 3739 O O . ASN A 1 488 ? -17.501 -18.476 65.707 1.00 20.62 ? 508 ASN A O 1 ATOM 3740 C CB . ASN A 1 488 ? -17.565 -19.612 68.616 1.00 20.33 ? 508 ASN A CB 1 ATOM 3741 C CG . ASN A 1 488 ? -17.175 -19.658 70.091 1.00 19.84 ? 508 ASN A CG 1 ATOM 3742 O OD1 . ASN A 1 488 ? -16.725 -18.665 70.651 1.00 20.29 ? 508 ASN A OD1 1 ATOM 3743 N ND2 . ASN A 1 488 ? -17.345 -20.807 70.714 1.00 19.23 ? 508 ASN A ND2 1 ATOM 3744 N N . ILE A 1 489 ? -16.446 -20.501 65.674 1.00 20.30 ? 509 ILE A N 1 ATOM 3745 C CA . ILE A 1 489 ? -16.917 -20.903 64.355 1.00 20.41 ? 509 ILE A CA 1 ATOM 3746 C C . ILE A 1 489 ? -18.424 -21.115 64.404 1.00 20.38 ? 509 ILE A C 1 ATOM 3747 O O . ILE A 1 489 ? -18.956 -21.620 65.394 1.00 20.50 ? 509 ILE A O 1 ATOM 3748 C CB . ILE A 1 489 ? -16.228 -22.208 63.867 1.00 20.71 ? 509 ILE A CB 1 ATOM 3749 C CG1 . ILE A 1 489 ? -16.486 -22.430 62.369 1.00 21.28 ? 509 ILE A CG1 1 ATOM 3750 C CG2 . ILE A 1 489 ? -16.679 -23.414 64.686 1.00 19.56 ? 509 ILE A CG2 1 ATOM 3751 C CD1 . ILE A 1 489 ? -15.715 -23.630 61.767 1.00 20.77 ? 509 ILE A CD1 1 ATOM 3752 N N . HIS A 1 490 ? -19.104 -20.699 63.341 1.00 19.97 ? 510 HIS A N 1 ATOM 3753 C CA . HIS A 1 490 ? -20.541 -20.870 63.232 1.00 19.66 ? 510 HIS A CA 1 ATOM 3754 C C . HIS A 1 490 ? -21.008 -20.744 61.799 1.00 19.92 ? 510 HIS A C 1 ATOM 3755 O O . HIS A 1 490 ? -20.282 -20.263 60.933 1.00 19.86 ? 510 HIS A O 1 ATOM 3756 C CB . HIS A 1 490 ? -21.276 -19.829 64.093 1.00 19.66 ? 510 HIS A CB 1 ATOM 3757 C CG . HIS A 1 490 ? -20.965 -18.410 63.727 1.00 19.09 ? 510 HIS A CG 1 ATOM 3758 N ND1 . HIS A 1 490 ? -19.748 -17.824 63.996 1.00 18.03 ? 510 HIS A ND1 1 ATOM 3759 C CD2 . HIS A 1 490 ? -21.711 -17.462 63.106 1.00 20.09 ? 510 HIS A CD2 1 ATOM 3760 C CE1 . HIS A 1 490 ? -19.756 -16.577 63.559 1.00 19.46 ? 510 HIS A CE1 1 ATOM 3761 N NE2 . HIS A 1 490 ? -20.938 -16.328 63.017 1.00 18.88 ? 510 HIS A NE2 1 ATOM 3762 N N . THR A 1 491 ? -22.246 -21.155 61.568 1.00 20.21 ? 511 THR A N 1 ATOM 3763 C CA . THR A 1 491 ? -22.884 -20.974 60.283 1.00 20.41 ? 511 THR A CA 1 ATOM 3764 C C . THR A 1 491 ? -24.170 -20.195 60.484 1.00 20.74 ? 511 THR A C 1 ATOM 3765 O O . THR A 1 491 ? -24.984 -20.540 61.349 1.00 20.84 ? 511 THR A O 1 ATOM 3766 C CB . THR A 1 491 ? -23.175 -22.336 59.622 1.00 20.67 ? 511 THR A CB 1 ATOM 3767 O OG1 . THR A 1 491 ? -21.936 -23.029 59.421 1.00 20.93 ? 511 THR A OG1 1 ATOM 3768 C CG2 . THR A 1 491 ? -23.874 -22.170 58.281 1.00 20.99 ? 511 THR A CG2 1 ATOM 3769 N N . HIS A 1 492 ? -24.330 -19.135 59.690 1.00 20.47 ? 512 HIS A N 1 ATOM 3770 C CA . HIS A 1 492 ? -25.575 -18.400 59.590 1.00 20.36 ? 512 HIS A CA 1 ATOM 3771 C C . HIS A 1 492 ? -26.433 -19.092 58.559 1.00 20.23 ? 512 HIS A C 1 ATOM 3772 O O . HIS A 1 492 ? -25.965 -19.361 57.462 1.00 20.36 ? 512 HIS A O 1 ATOM 3773 C CB . HIS A 1 492 ? -25.346 -16.961 59.103 1.00 20.21 ? 512 HIS A CB 1 ATOM 3774 C CG . HIS A 1 492 ? -24.547 -16.118 60.038 1.00 20.81 ? 512 HIS A CG 1 ATOM 3775 N ND1 . HIS A 1 492 ? -25.110 -15.446 61.101 1.00 20.79 ? 512 HIS A ND1 1 ATOM 3776 C CD2 . HIS A 1 492 ? -23.223 -15.829 60.066 1.00 21.42 ? 512 HIS A CD2 1 ATOM 3777 C CE1 . HIS A 1 492 ? -24.168 -14.778 61.744 1.00 20.22 ? 512 HIS A CE1 1 ATOM 3778 N NE2 . HIS A 1 492 ? -23.016 -14.992 61.135 1.00 22.34 ? 512 HIS A NE2 1 ATOM 3779 N N . LEU A 1 493 ? -27.691 -19.357 58.895 1.00 20.01 ? 513 LEU A N 1 ATOM 3780 C CA . LEU A 1 493 ? -28.650 -19.885 57.925 1.00 19.80 ? 513 LEU A CA 1 ATOM 3781 C C . LEU A 1 493 ? -29.953 -19.121 58.055 1.00 19.64 ? 513 LEU A C 1 ATOM 3782 O O . LEU A 1 493 ? -30.459 -18.953 59.165 1.00 19.84 ? 513 LEU A O 1 ATOM 3783 C CB . LEU A 1 493 ? -28.908 -21.370 58.151 1.00 19.89 ? 513 LEU A CB 1 ATOM 3784 C CG . LEU A 1 493 ? -27.710 -22.327 58.037 1.00 20.72 ? 513 LEU A CG 1 ATOM 3785 C CD1 . LEU A 1 493 ? -28.041 -23.706 58.599 1.00 19.65 ? 513 LEU A CD1 1 ATOM 3786 C CD2 . LEU A 1 493 ? -27.247 -22.442 56.580 1.00 18.98 ? 513 LEU A CD2 1 ATOM 3787 N N . VAL A 1 494 ? -30.483 -18.650 56.927 1.00 18.76 ? 514 VAL A N 1 ATOM 3788 C CA . VAL A 1 494 ? -31.766 -17.974 56.896 1.00 18.24 ? 514 VAL A CA 1 ATOM 3789 C C . VAL A 1 494 ? -32.737 -18.748 56.019 1.00 18.16 ? 514 VAL A C 1 ATOM 3790 O O . VAL A 1 494 ? -32.370 -19.228 54.946 1.00 17.79 ? 514 VAL A O 1 ATOM 3791 C CB . VAL A 1 494 ? -31.661 -16.524 56.374 1.00 18.15 ? 514 VAL A CB 1 ATOM 3792 C CG1 . VAL A 1 494 ? -33.039 -15.883 56.339 1.00 17.73 ? 514 VAL A CG1 1 ATOM 3793 C CG2 . VAL A 1 494 ? -30.697 -15.690 57.254 1.00 17.62 ? 514 VAL A CG2 1 ATOM 3794 N N . HIS A 1 495 ? -33.974 -18.875 56.495 1.00 17.37 ? 515 HIS A N 1 ATOM 3795 C CA . HIS A 1 495 ? -35.026 -19.486 55.710 1.00 17.41 ? 515 HIS A CA 1 ATOM 3796 C C . HIS A 1 495 ? -36.042 -18.446 55.247 1.00 17.19 ? 515 HIS A C 1 ATOM 3797 O O . HIS A 1 495 ? -36.502 -17.623 56.037 1.00 16.79 ? 515 HIS A O 1 ATOM 3798 C CB . HIS A 1 495 ? -35.737 -20.586 56.497 1.00 17.17 ? 515 HIS A CB 1 ATOM 3799 C CG . HIS A 1 495 ? -36.378 -21.617 55.620 1.00 17.23 ? 515 HIS A CG 1 ATOM 3800 N ND1 . HIS A 1 495 ? -37.669 -22.065 55.812 1.00 16.44 ? 515 HIS A ND1 1 ATOM 3801 C CD2 . HIS A 1 495 ? -35.907 -22.273 54.529 1.00 16.93 ? 515 HIS A CD2 1 ATOM 3802 C CE1 . HIS A 1 495 ? -37.954 -22.969 54.889 1.00 17.18 ? 515 HIS A CE1 1 ATOM 3803 N NE2 . HIS A 1 495 ? -36.908 -23.105 54.092 1.00 14.82 ? 515 HIS A NE2 1 ATOM 3804 N N . TYR A 1 496 ? -36.383 -18.507 53.961 1.00 16.96 ? 516 TYR A N 1 ATOM 3805 C CA . TYR A 1 496 ? -37.396 -17.625 53.369 1.00 16.75 ? 516 TYR A CA 1 ATOM 3806 C C . TYR A 1 496 ? -38.568 -18.422 52.836 1.00 16.33 ? 516 TYR A C 1 ATOM 3807 O O . TYR A 1 496 ? -38.380 -19.502 52.265 1.00 16.48 ? 516 TYR A O 1 ATOM 3808 C CB . TYR A 1 496 ? -36.815 -16.841 52.201 1.00 16.13 ? 516 TYR A CB 1 ATOM 3809 C CG . TYR A 1 496 ? -35.971 -15.655 52.568 1.00 17.28 ? 516 TYR A CG 1 ATOM 3810 C CD1 . TYR A 1 496 ? -34.580 -15.763 52.640 1.00 18.06 ? 516 TYR A CD1 1 ATOM 3811 C CD2 . TYR A 1 496 ? -36.545 -14.399 52.772 1.00 16.59 ? 516 TYR A CD2 1 ATOM 3812 C CE1 . TYR A 1 496 ? -33.791 -14.668 52.944 1.00 17.46 ? 516 TYR A CE1 1 ATOM 3813 C CE2 . TYR A 1 496 ? -35.762 -13.304 53.063 1.00 17.40 ? 516 TYR A CE2 1 ATOM 3814 C CZ . TYR A 1 496 ? -34.385 -13.446 53.159 1.00 17.13 ? 516 TYR A CZ 1 ATOM 3815 O OH . TYR A 1 496 ? -33.606 -12.362 53.461 1.00 19.06 ? 516 TYR A OH 1 ATOM 3816 N N . ARG A 1 497 ? -39.769 -17.866 53.000 1.00 15.84 ? 517 ARG A N 1 ATOM 3817 C CA . ARG A 1 497 ? -40.978 -18.395 52.372 1.00 15.45 ? 517 ARG A CA 1 ATOM 3818 C C . ARG A 1 497 ? -41.259 -17.550 51.158 1.00 15.20 ? 517 ARG A C 1 ATOM 3819 O O . ARG A 1 497 ? -41.340 -16.325 51.252 1.00 15.43 ? 517 ARG A O 1 ATOM 3820 C CB . ARG A 1 497 ? -42.174 -18.321 53.316 1.00 15.27 ? 517 ARG A CB 1 ATOM 3821 C CG . ARG A 1 497 ? -43.491 -18.859 52.727 1.00 14.63 ? 517 ARG A CG 1 ATOM 3822 C CD . ARG A 1 497 ? -44.628 -18.680 53.719 1.00 15.18 ? 517 ARG A CD 1 ATOM 3823 N NE . ARG A 1 497 ? -45.964 -18.860 53.126 1.00 16.64 ? 517 ARG A NE 1 ATOM 3824 C CZ . ARG A 1 497 ? -46.608 -20.025 52.998 1.00 15.96 ? 517 ARG A CZ 1 ATOM 3825 N NH1 . ARG A 1 497 ? -46.062 -21.155 53.410 1.00 14.47 ? 517 ARG A NH1 1 ATOM 3826 N NH2 . ARG A 1 497 ? -47.819 -20.053 52.452 1.00 17.24 ? 517 ARG A NH2 1 ATOM 3827 N N . VAL A 1 498 ? -41.421 -18.201 50.018 1.00 15.28 ? 518 VAL A N 1 ATOM 3828 C CA . VAL A 1 498 ? -41.581 -17.497 48.756 1.00 15.14 ? 518 VAL A CA 1 ATOM 3829 C C . VAL A 1 498 ? -42.804 -18.047 48.035 1.00 15.25 ? 518 VAL A C 1 ATOM 3830 O O . VAL A 1 498 ? -42.707 -18.922 47.177 1.00 14.78 ? 518 VAL A O 1 ATOM 3831 C CB . VAL A 1 498 ? -40.298 -17.583 47.896 1.00 15.36 ? 518 VAL A CB 1 ATOM 3832 C CG1 . VAL A 1 498 ? -40.385 -16.605 46.740 1.00 15.47 ? 518 VAL A CG1 1 ATOM 3833 C CG2 . VAL A 1 498 ? -39.046 -17.306 48.749 1.00 15.12 ? 518 VAL A CG2 1 ATOM 3834 N N . ASP A 1 499 ? -43.972 -17.541 48.431 1.00 15.73 ? 519 ASP A N 1 ATOM 3835 C CA . ASP A 1 499 ? -45.236 -17.996 47.866 1.00 16.11 ? 519 ASP A CA 1 ATOM 3836 C C . ASP A 1 499 ? -45.447 -17.275 46.546 1.00 16.38 ? 519 ASP A C 1 ATOM 3837 O O . ASP A 1 499 ? -46.119 -16.248 46.482 1.00 16.42 ? 519 ASP A O 1 ATOM 3838 C CB . ASP A 1 499 ? -46.394 -17.734 48.843 1.00 15.79 ? 519 ASP A CB 1 ATOM 3839 C CG . ASP A 1 499 ? -47.736 -18.242 48.322 1.00 15.71 ? 519 ASP A CG 1 ATOM 3840 O OD1 . ASP A 1 499 ? -47.772 -18.908 47.262 1.00 15.46 ? 519 ASP A OD1 1 ATOM 3841 O OD2 . ASP A 1 499 ? -48.764 -17.991 48.990 1.00 16.50 ? 519 ASP A OD2 1 ATOM 3842 N N . LEU A 1 500 ? -44.832 -17.806 45.495 1.00 17.24 ? 520 LEU A N 1 ATOM 3843 C CA . LEU A 1 500 ? -45.001 -17.271 44.157 1.00 17.72 ? 520 LEU A CA 1 ATOM 3844 C C . LEU A 1 500 ? -46.387 -17.678 43.636 1.00 17.55 ? 520 LEU A C 1 ATOM 3845 O O . LEU A 1 500 ? -46.796 -18.828 43.789 1.00 16.97 ? 520 LEU A O 1 ATOM 3846 C CB . LEU A 1 500 ? -43.899 -17.775 43.220 1.00 18.13 ? 520 LEU A CB 1 ATOM 3847 C CG . LEU A 1 500 ? -42.483 -17.267 43.552 1.00 19.55 ? 520 LEU A CG 1 ATOM 3848 C CD1 . LEU A 1 500 ? -41.404 -18.198 43.006 1.00 19.38 ? 520 LEU A CD1 1 ATOM 3849 C CD2 . LEU A 1 500 ? -42.262 -15.834 43.063 1.00 20.49 ? 520 LEU A CD2 1 ATOM 3850 N N . ASP A 1 501 ? -47.108 -16.709 43.072 1.00 17.97 ? 521 ASP A N 1 ATOM 3851 C CA . ASP A 1 501 ? -48.340 -16.943 42.326 1.00 18.26 ? 521 ASP A CA 1 ATOM 3852 C C . ASP A 1 501 ? -48.124 -16.331 40.945 1.00 18.30 ? 521 ASP A C 1 ATOM 3853 O O . ASP A 1 501 ? -48.562 -15.217 40.663 1.00 18.06 ? 521 ASP A O 1 ATOM 3854 C CB . ASP A 1 501 ? -49.546 -16.262 42.987 1.00 18.73 ? 521 ASP A CB 1 ATOM 3855 C CG . ASP A 1 501 ? -50.042 -16.961 44.234 1.00 18.92 ? 521 ASP A CG 1 ATOM 3856 O OD1 . ASP A 1 501 ? -49.489 -17.988 44.672 1.00 18.49 ? 521 ASP A OD1 1 ATOM 3857 O OD2 . ASP A 1 501 ? -51.027 -16.446 44.800 1.00 22.02 ? 521 ASP A OD2 1 ATOM 3858 N N . VAL A 1 502 ? -47.460 -17.070 40.071 1.00 18.46 ? 522 VAL A N 1 ATOM 3859 C CA . VAL A 1 502 ? -47.021 -16.499 38.802 1.00 18.80 ? 522 VAL A CA 1 ATOM 3860 C C . VAL A 1 502 ? -48.225 -16.320 37.874 1.00 19.61 ? 522 VAL A C 1 ATOM 3861 O O . VAL A 1 502 ? -48.847 -17.289 37.455 1.00 20.27 ? 522 VAL A O 1 ATOM 3862 C CB . VAL A 1 502 ? -45.893 -17.330 38.173 1.00 18.54 ? 522 VAL A CB 1 ATOM 3863 C CG1 . VAL A 1 502 ? -45.344 -16.628 36.938 1.00 17.92 ? 522 VAL A CG1 1 ATOM 3864 C CG2 . VAL A 1 502 ? -44.773 -17.577 39.231 1.00 17.18 ? 522 VAL A CG2 1 ATOM 3865 N N . ALA A 1 503 ? -48.567 -15.063 37.610 1.00 20.49 ? 523 ALA A N 1 ATOM 3866 C CA . ALA A 1 503 ? -49.761 -14.688 36.862 1.00 21.24 ? 523 ALA A CA 1 ATOM 3867 C C . ALA A 1 503 ? -51.046 -15.328 37.412 1.00 22.31 ? 523 ALA A C 1 ATOM 3868 O O . ALA A 1 503 ? -52.020 -15.455 36.693 1.00 22.65 ? 523 ALA A O 1 ATOM 3869 C CB . ALA A 1 503 ? -49.582 -15.030 35.393 1.00 20.94 ? 523 ALA A CB 1 ATOM 3870 N N . GLY A 1 504 ? -51.061 -15.705 38.688 1.00 23.55 ? 524 GLY A N 1 ATOM 3871 C CA . GLY A 1 504 ? -52.163 -16.505 39.237 1.00 24.11 ? 524 GLY A CA 1 ATOM 3872 C C . GLY A 1 504 ? -51.692 -17.540 40.244 1.00 24.84 ? 524 GLY A C 1 ATOM 3873 O O . GLY A 1 504 ? -50.490 -17.804 40.383 1.00 24.12 ? 524 GLY A O 1 ATOM 3874 N N . THR A 1 505 ? -52.662 -18.133 40.934 1.00 25.31 ? 525 THR A N 1 ATOM 3875 C CA A THR A 1 505 ? -52.414 -19.127 41.961 0.60 25.62 ? 525 THR A CA 1 ATOM 3876 C CA B THR A 1 505 ? -52.383 -19.130 41.969 0.40 25.38 ? 525 THR A CA 1 ATOM 3877 C C . THR A 1 505 ? -51.803 -20.413 41.399 1.00 25.69 ? 525 THR A C 1 ATOM 3878 O O . THR A 1 505 ? -50.852 -20.941 41.950 1.00 25.76 ? 525 THR A O 1 ATOM 3879 C CB A THR A 1 505 ? -53.741 -19.461 42.666 0.60 25.94 ? 525 THR A CB 1 ATOM 3880 C CB B THR A 1 505 ? -53.644 -19.504 42.783 0.40 25.56 ? 525 THR A CB 1 ATOM 3881 O OG1 A THR A 1 505 ? -54.490 -18.249 42.854 0.60 26.21 ? 525 THR A OG1 1 ATOM 3882 O OG1 B THR A 1 505 ? -54.783 -19.540 41.913 0.40 24.94 ? 525 THR A OG1 1 ATOM 3883 C CG2 A THR A 1 505 ? -53.487 -20.111 43.998 0.60 25.81 ? 525 THR A CG2 1 ATOM 3884 C CG2 B THR A 1 505 ? -53.875 -18.498 43.918 0.40 25.02 ? 525 THR A CG2 1 ATOM 3885 N N . LYS A 1 506 ? -52.360 -20.909 40.288 1.00 25.86 ? 526 LYS A N 1 ATOM 3886 C CA . LYS A 1 506 ? -51.966 -22.228 39.757 1.00 25.73 ? 526 LYS A CA 1 ATOM 3887 C C . LYS A 1 506 ? -50.693 -22.197 38.913 1.00 23.93 ? 526 LYS A C 1 ATOM 3888 O O . LYS A 1 506 ? -50.677 -21.662 37.804 1.00 23.44 ? 526 LYS A O 1 ATOM 3889 C CB . LYS A 1 506 ? -53.102 -22.858 38.948 1.00 26.52 ? 526 LYS A CB 1 ATOM 3890 C CG . LYS A 1 506 ? -54.383 -23.127 39.763 1.00 30.09 ? 526 LYS A CG 1 ATOM 3891 C CD . LYS A 1 506 ? -54.237 -24.336 40.688 1.00 33.17 ? 526 LYS A CD 1 ATOM 3892 C CE . LYS A 1 506 ? -55.584 -24.776 41.264 1.00 34.97 ? 526 LYS A CE 1 ATOM 3893 N NZ . LYS A 1 506 ? -56.568 -25.115 40.183 1.00 37.44 ? 526 LYS A NZ 1 ATOM 3894 N N . ASN A 1 507 ? -49.648 -22.813 39.452 1.00 22.19 ? 527 ASN A N 1 ATOM 3895 C CA . ASN A 1 507 ? -48.353 -22.887 38.811 1.00 21.23 ? 527 ASN A CA 1 ATOM 3896 C C . ASN A 1 507 ? -47.793 -24.312 38.736 1.00 20.64 ? 527 ASN A C 1 ATOM 3897 O O . ASN A 1 507 ? -48.316 -25.260 39.355 1.00 20.01 ? 527 ASN A O 1 ATOM 3898 C CB . ASN A 1 507 ? -47.345 -22.032 39.577 1.00 21.09 ? 527 ASN A CB 1 ATOM 3899 C CG . ASN A 1 507 ? -47.676 -20.549 39.566 1.00 20.36 ? 527 ASN A CG 1 ATOM 3900 O OD1 . ASN A 1 507 ? -47.372 -19.825 40.529 1.00 17.70 ? 527 ASN A OD1 1 ATOM 3901 N ND2 . ASN A 1 507 ? -48.265 -20.078 38.470 1.00 19.85 ? 527 ASN A ND2 1 ATOM 3902 N N . SER A 1 508 ? -46.733 -24.445 37.943 1.00 19.75 ? 528 SER A N 1 ATOM 3903 C CA A SER A 1 508 ? -45.924 -25.650 37.944 0.50 19.58 ? 528 SER A CA 1 ATOM 3904 C CA B SER A 1 508 ? -45.913 -25.649 37.911 0.50 19.82 ? 528 SER A CA 1 ATOM 3905 C C . SER A 1 508 ? -44.468 -25.253 38.167 1.00 19.40 ? 528 SER A C 1 ATOM 3906 O O . SER A 1 508 ? -44.135 -24.065 38.191 1.00 19.13 ? 528 SER A O 1 ATOM 3907 C CB A SER A 1 508 ? -46.111 -26.426 36.638 0.50 19.67 ? 528 SER A CB 1 ATOM 3908 C CB B SER A 1 508 ? -46.026 -26.364 36.562 0.50 19.96 ? 528 SER A CB 1 ATOM 3909 O OG A SER A 1 508 ? -47.459 -26.863 36.499 0.50 19.30 ? 528 SER A OG 1 ATOM 3910 O OG B SER A 1 508 ? -45.375 -25.638 35.530 0.50 21.09 ? 528 SER A OG 1 ATOM 3911 N N . PHE A 1 509 ? -43.618 -26.246 38.370 1.00 19.25 ? 529 PHE A N 1 ATOM 3912 C CA . PHE A 1 509 ? -42.203 -26.011 38.585 1.00 19.41 ? 529 PHE A CA 1 ATOM 3913 C C . PHE A 1 509 ? -41.421 -26.852 37.592 1.00 19.95 ? 529 PHE A C 1 ATOM 3914 O O . PHE A 1 509 ? -41.723 -28.016 37.403 1.00 20.53 ? 529 PHE A O 1 ATOM 3915 C CB . PHE A 1 509 ? -41.808 -26.367 40.016 1.00 19.00 ? 529 PHE A CB 1 ATOM 3916 C CG . PHE A 1 509 ? -40.329 -26.287 40.274 1.00 18.36 ? 529 PHE A CG 1 ATOM 3917 C CD1 . PHE A 1 509 ? -39.687 -25.055 40.323 1.00 16.03 ? 529 PHE A CD1 1 ATOM 3918 C CD2 . PHE A 1 509 ? -39.578 -27.440 40.463 1.00 16.94 ? 529 PHE A CD2 1 ATOM 3919 C CE1 . PHE A 1 509 ? -38.316 -24.966 40.559 1.00 17.42 ? 529 PHE A CE1 1 ATOM 3920 C CE2 . PHE A 1 509 ? -38.209 -27.359 40.693 1.00 17.91 ? 529 PHE A CE2 1 ATOM 3921 C CZ . PHE A 1 509 ? -37.576 -26.112 40.745 1.00 16.98 ? 529 PHE A CZ 1 ATOM 3922 N N . GLN A 1 510 ? -40.431 -26.248 36.947 1.00 20.44 ? 530 GLN A N 1 ATOM 3923 C CA . GLN A 1 510 ? -39.558 -26.955 36.018 1.00 20.90 ? 530 GLN A CA 1 ATOM 3924 C C . GLN A 1 510 ? -38.165 -26.351 36.083 1.00 20.53 ? 530 GLN A C 1 ATOM 3925 O O . GLN A 1 510 ? -37.978 -25.254 36.616 1.00 20.71 ? 530 GLN A O 1 ATOM 3926 C CB . GLN A 1 510 ? -40.107 -26.892 34.584 1.00 21.33 ? 530 GLN A CB 1 ATOM 3927 C CG . GLN A 1 510 ? -40.170 -25.503 33.983 1.00 23.07 ? 530 GLN A CG 1 ATOM 3928 C CD . GLN A 1 510 ? -40.493 -25.506 32.490 1.00 25.95 ? 530 GLN A CD 1 ATOM 3929 O OE1 . GLN A 1 510 ? -41.027 -26.476 31.939 1.00 30.12 ? 530 GLN A OE1 1 ATOM 3930 N NE2 . GLN A 1 510 ? -40.172 -24.419 31.836 1.00 26.34 ? 530 GLN A NE2 1 ATOM 3931 N N . THR A 1 511 ? -37.189 -27.076 35.557 1.00 20.28 ? 531 THR A N 1 ATOM 3932 C CA . THR A 1 511 ? -35.820 -26.576 35.497 1.00 20.08 ? 531 THR A CA 1 ATOM 3933 C C . THR A 1 511 ? -35.286 -26.713 34.086 1.00 19.96 ? 531 THR A C 1 ATOM 3934 O O . THR A 1 511 ? -35.801 -27.513 33.297 1.00 19.59 ? 531 THR A O 1 ATOM 3935 C CB . THR A 1 511 ? -34.880 -27.296 36.497 1.00 20.03 ? 531 THR A CB 1 ATOM 3936 O OG1 . THR A 1 511 ? -34.835 -28.698 36.217 1.00 21.52 ? 531 THR A OG1 1 ATOM 3937 C CG2 . THR A 1 511 ? -35.342 -27.077 37.942 1.00 20.09 ? 531 THR A CG2 1 ATOM 3938 N N . LEU A 1 512 ? -34.278 -25.901 33.764 1.00 19.98 ? 532 LEU A N 1 ATOM 3939 C CA . LEU A 1 512 ? -33.591 -25.976 32.486 1.00 20.16 ? 532 LEU A CA 1 ATOM 3940 C C . LEU A 1 512 ? -32.096 -26.142 32.727 1.00 20.62 ? 532 LEU A C 1 ATOM 3941 O O . LEU A 1 512 ? -31.533 -25.559 33.661 1.00 20.75 ? 532 LEU A O 1 ATOM 3942 C CB . LEU A 1 512 ? -33.841 -24.735 31.628 1.00 19.98 ? 532 LEU A CB 1 ATOM 3943 C CG . LEU A 1 512 ? -35.273 -24.205 31.501 1.00 21.17 ? 532 LEU A CG 1 ATOM 3944 C CD1 . LEU A 1 512 ? -35.259 -22.812 30.839 1.00 19.25 ? 532 LEU A CD1 1 ATOM 3945 C CD2 . LEU A 1 512 ? -36.221 -25.184 30.759 1.00 18.11 ? 532 LEU A CD2 1 ATOM 3946 N N . GLN A 1 513 ? -31.475 -26.956 31.883 1.00 20.93 ? 533 GLN A N 1 ATOM 3947 C CA . GLN A 1 513 ? -30.052 -27.209 31.935 1.00 21.40 ? 533 GLN A CA 1 ATOM 3948 C C . GLN A 1 513 ? -29.508 -27.218 30.520 1.00 21.66 ? 533 GLN A C 1 ATOM 3949 O O . GLN A 1 513 ? -30.249 -27.462 29.560 1.00 21.50 ? 533 GLN A O 1 ATOM 3950 C CB . GLN A 1 513 ? -29.770 -28.564 32.610 1.00 21.60 ? 533 GLN A CB 1 ATOM 3951 N N . MET A 1 514 ? -28.217 -26.933 30.390 1.00 22.03 ? 534 MET A N 1 ATOM 3952 C CA . MET A 1 514 ? -27.531 -27.148 29.136 1.00 22.73 ? 534 MET A CA 1 ATOM 3953 C C . MET A 1 514 ? -27.086 -28.594 29.095 1.00 22.96 ? 534 MET A C 1 ATOM 3954 O O . MET A 1 514 ? -26.538 -29.097 30.068 1.00 23.48 ? 534 MET A O 1 ATOM 3955 C CB . MET A 1 514 ? -26.315 -26.240 28.997 1.00 22.95 ? 534 MET A CB 1 ATOM 3956 C CG . MET A 1 514 ? -25.666 -26.332 27.619 1.00 24.12 ? 534 MET A CG 1 ATOM 3957 S SD . MET A 1 514 ? -24.338 -27.556 27.505 1.00 26.01 ? 534 MET A SD 1 ATOM 3958 C CE . MET A 1 514 ? -23.023 -26.665 28.318 1.00 26.32 ? 534 MET A CE 1 ATOM 3959 N N . LYS A 1 515 ? -27.345 -29.267 27.979 1.00 23.19 ? 535 LYS A N 1 ATOM 3960 C CA . LYS A 1 515 ? -26.828 -30.613 27.753 1.00 23.22 ? 535 LYS A CA 1 ATOM 3961 C C . LYS A 1 515 ? -26.197 -30.657 26.365 1.00 23.03 ? 535 LYS A C 1 ATOM 3962 O O . LYS A 1 515 ? -26.781 -30.171 25.404 1.00 22.71 ? 535 LYS A O 1 ATOM 3963 C CB . LYS A 1 515 ? -27.946 -31.644 27.863 1.00 23.47 ? 535 LYS A CB 1 ATOM 3964 C CG . LYS A 1 515 ? -27.473 -33.080 27.875 1.00 25.18 ? 535 LYS A CG 1 ATOM 3965 C CD . LYS A 1 515 ? -28.505 -34.000 28.535 1.00 27.40 ? 535 LYS A CD 1 ATOM 3966 N N . LEU A 1 516 ? -25.000 -31.224 26.269 1.00 22.63 ? 536 LEU A N 1 ATOM 3967 C CA . LEU A 1 516 ? -24.312 -31.300 24.996 1.00 22.89 ? 536 LEU A CA 1 ATOM 3968 C C . LEU A 1 516 ? -24.906 -32.416 24.149 1.00 22.80 ? 536 LEU A C 1 ATOM 3969 O O . LEU A 1 516 ? -25.359 -33.427 24.668 1.00 23.23 ? 536 LEU A O 1 ATOM 3970 C CB . LEU A 1 516 ? -22.805 -31.557 25.184 1.00 22.59 ? 536 LEU A CB 1 ATOM 3971 C CG . LEU A 1 516 ? -21.971 -30.498 25.916 1.00 22.85 ? 536 LEU A CG 1 ATOM 3972 C CD1 . LEU A 1 516 ? -20.542 -31.000 26.096 1.00 22.63 ? 536 LEU A CD1 1 ATOM 3973 C CD2 . LEU A 1 516 ? -21.970 -29.143 25.190 1.00 22.60 ? 536 LEU A CD2 1 ATOM 3974 N N . GLU A 1 517 ? -24.909 -32.214 22.842 1.00 23.11 ? 537 GLU A N 1 ATOM 3975 C CA . GLU A 1 517 ? -25.145 -33.288 21.883 1.00 23.06 ? 537 GLU A CA 1 ATOM 3976 C C . GLU A 1 517 ? -23.894 -33.403 21.004 1.00 23.69 ? 537 GLU A C 1 ATOM 3977 O O . GLU A 1 517 ? -23.070 -32.491 20.935 1.00 23.40 ? 537 GLU A O 1 ATOM 3978 C CB . GLU A 1 517 ? -26.371 -32.995 21.016 1.00 22.96 ? 537 GLU A CB 1 ATOM 3979 C CG . GLU A 1 517 ? -26.198 -31.813 20.073 1.00 22.47 ? 537 GLU A CG 1 ATOM 3980 C CD . GLU A 1 517 ? -27.376 -31.595 19.143 1.00 22.09 ? 537 GLU A CD 1 ATOM 3981 O OE1 . GLU A 1 517 ? -28.373 -32.333 19.227 1.00 22.46 ? 537 GLU A OE1 1 ATOM 3982 O OE2 . GLU A 1 517 ? -27.298 -30.668 18.318 1.00 22.00 ? 537 GLU A OE2 1 ATOM 3983 N N . ASN A 1 518 ? -23.785 -34.537 20.331 1.00 24.19 ? 538 ASN A N 1 ATOM 3984 C CA . ASN A 1 518 ? -22.661 -34.851 19.492 1.00 24.67 ? 538 ASN A CA 1 ATOM 3985 C C . ASN A 1 518 ? -23.268 -35.376 18.211 1.00 24.85 ? 538 ASN A C 1 ATOM 3986 O O . ASN A 1 518 ? -23.789 -36.492 18.172 1.00 24.64 ? 538 ASN A O 1 ATOM 3987 C CB . ASN A 1 518 ? -21.785 -35.892 20.190 1.00 24.93 ? 538 ASN A CB 1 ATOM 3988 C CG . ASN A 1 518 ? -20.596 -36.330 19.355 1.00 25.91 ? 538 ASN A CG 1 ATOM 3989 O OD1 . ASN A 1 518 ? -20.469 -35.968 18.181 1.00 25.34 ? 538 ASN A OD1 1 ATOM 3990 N ND2 . ASN A 1 518 ? -19.705 -37.115 19.972 1.00 27.21 ? 538 ASN A ND2 1 ATOM 3991 N N . ILE A 1 519 ? -23.265 -34.531 17.182 1.00 25.16 ? 539 ILE A N 1 ATOM 3992 C CA . ILE A 1 519 ? -23.882 -34.870 15.903 1.00 25.27 ? 539 ILE A CA 1 ATOM 3993 C C . ILE A 1 519 ? -22.856 -34.786 14.781 1.00 25.28 ? 539 ILE A C 1 ATOM 3994 O O . ILE A 1 519 ? -21.780 -34.210 14.945 1.00 24.86 ? 539 ILE A O 1 ATOM 3995 C CB . ILE A 1 519 ? -25.076 -33.939 15.569 1.00 25.05 ? 539 ILE A CB 1 ATOM 3996 C CG1 . ILE A 1 519 ? -24.636 -32.473 15.531 1.00 25.68 ? 539 ILE A CG1 1 ATOM 3997 C CG2 . ILE A 1 519 ? -26.195 -34.123 16.585 1.00 25.30 ? 539 ILE A CG2 1 ATOM 3998 C CD1 . ILE A 1 519 ? -25.672 -31.530 14.957 1.00 25.42 ? 539 ILE A CD1 1 ATOM 3999 N N . THR A 1 520 ? -23.209 -35.387 13.647 1.00 25.51 ? 540 THR A N 1 ATOM 4000 C CA . THR A 1 520 ? -22.492 -35.186 12.396 1.00 25.29 ? 540 THR A CA 1 ATOM 4001 C C . THR A 1 520 ? -22.554 -33.706 12.057 1.00 25.14 ? 540 THR A C 1 ATOM 4002 O O . THR A 1 520 ? -23.625 -33.101 12.129 1.00 24.86 ? 540 THR A O 1 ATOM 4003 C CB . THR A 1 520 ? -23.140 -36.000 11.255 1.00 25.19 ? 540 THR A CB 1 ATOM 4004 O OG1 . THR A 1 520 ? -23.117 -37.384 11.602 1.00 26.37 ? 540 THR A OG1 1 ATOM 4005 C CG2 . THR A 1 520 ? -22.408 -35.791 9.917 1.00 25.37 ? 540 THR A CG2 1 ATOM 4006 N N . ASN A 1 521 ? -21.404 -33.123 11.726 1.00 25.17 ? 541 ASN A N 1 ATOM 4007 C CA . ASN A 1 521 ? -21.353 -31.748 11.235 1.00 25.53 ? 541 ASN A CA 1 ATOM 4008 C C . ASN A 1 521 ? -22.116 -31.693 9.912 1.00 25.92 ? 541 ASN A C 1 ATOM 4009 O O . ASN A 1 521 ? -21.664 -32.279 8.917 1.00 25.90 ? 541 ASN A O 1 ATOM 4010 C CB . ASN A 1 521 ? -19.905 -31.280 11.059 1.00 25.33 ? 541 ASN A CB 1 ATOM 4011 C CG . ASN A 1 521 ? -19.798 -29.878 10.483 1.00 25.37 ? 541 ASN A CG 1 ATOM 4012 O OD1 . ASN A 1 521 ? -20.667 -29.429 9.735 1.00 24.08 ? 541 ASN A OD1 1 ATOM 4013 N ND2 . ASN A 1 521 ? -18.715 -29.177 10.832 1.00 24.94 ? 541 ASN A ND2 1 ATOM 4014 N N . PRO A 1 522 ? -23.265 -30.984 9.897 1.00 26.44 ? 542 PRO A N 1 ATOM 4015 C CA . PRO A 1 522 ? -24.194 -31.033 8.771 1.00 27.00 ? 542 PRO A CA 1 ATOM 4016 C C . PRO A 1 522 ? -23.640 -30.515 7.452 1.00 27.31 ? 542 PRO A C 1 ATOM 4017 O O . PRO A 1 522 ? -24.150 -30.901 6.410 1.00 28.23 ? 542 PRO A O 1 ATOM 4018 C CB . PRO A 1 522 ? -25.376 -30.144 9.224 1.00 27.10 ? 542 PRO A CB 1 ATOM 4019 C CG . PRO A 1 522 ? -25.131 -29.819 10.633 1.00 27.00 ? 542 PRO A CG 1 ATOM 4020 C CD . PRO A 1 522 ? -23.672 -29.967 10.883 1.00 26.61 ? 542 PRO A CD 1 ATOM 4021 N N . TRP A 1 523 ? -22.627 -29.651 7.497 1.00 27.35 ? 543 TRP A N 1 ATOM 4022 C CA . TRP A 1 523 ? -22.036 -29.061 6.288 1.00 27.28 ? 543 TRP A CA 1 ATOM 4023 C C . TRP A 1 523 ? -20.616 -29.583 6.018 1.00 27.96 ? 543 TRP A C 1 ATOM 4024 O O . TRP A 1 523 ? -19.966 -29.156 5.067 1.00 27.46 ? 543 TRP A O 1 ATOM 4025 C CB . TRP A 1 523 ? -22.026 -27.531 6.384 1.00 27.03 ? 543 TRP A CB 1 ATOM 4026 C CG . TRP A 1 523 ? -21.429 -26.987 7.663 1.00 25.75 ? 543 TRP A CG 1 ATOM 4027 C CD1 . TRP A 1 523 ? -22.086 -26.760 8.847 1.00 23.59 ? 543 TRP A CD1 1 ATOM 4028 C CD2 . TRP A 1 523 ? -20.062 -26.617 7.885 1.00 24.19 ? 543 TRP A CD2 1 ATOM 4029 N NE1 . TRP A 1 523 ? -21.210 -26.261 9.784 1.00 23.33 ? 543 TRP A NE1 1 ATOM 4030 C CE2 . TRP A 1 523 ? -19.961 -26.173 9.225 1.00 22.88 ? 543 TRP A CE2 1 ATOM 4031 C CE3 . TRP A 1 523 ? -18.915 -26.615 7.084 1.00 23.97 ? 543 TRP A CE3 1 ATOM 4032 C CZ2 . TRP A 1 523 ? -18.764 -25.732 9.776 1.00 23.02 ? 543 TRP A CZ2 1 ATOM 4033 C CZ3 . TRP A 1 523 ? -17.727 -26.172 7.626 1.00 23.67 ? 543 TRP A CZ3 1 ATOM 4034 C CH2 . TRP A 1 523 ? -17.657 -25.738 8.966 1.00 24.68 ? 543 TRP A CH2 1 ATOM 4035 N N . SER A 1 524 ? -20.142 -30.492 6.867 1.00 28.56 ? 544 SER A N 1 ATOM 4036 C CA . SER A 1 524 ? -18.850 -31.140 6.673 1.00 29.25 ? 544 SER A CA 1 ATOM 4037 C C . SER A 1 524 ? -18.930 -32.548 7.270 1.00 29.80 ? 544 SER A C 1 ATOM 4038 O O . SER A 1 524 ? -18.492 -32.767 8.394 1.00 29.73 ? 544 SER A O 1 ATOM 4039 C CB . SER A 1 524 ? -17.736 -30.320 7.322 1.00 29.33 ? 544 SER A CB 1 ATOM 4040 O OG . SER A 1 524 ? -16.458 -30.887 7.065 1.00 29.83 ? 544 SER A OG 1 ATOM 4041 N N . PRO A 1 525 ? -19.517 -33.502 6.512 1.00 30.73 ? 545 PRO A N 1 ATOM 4042 C CA . PRO A 1 525 ? -19.849 -34.880 6.931 1.00 30.85 ? 545 PRO A CA 1 ATOM 4043 C C . PRO A 1 525 ? -18.730 -35.633 7.664 1.00 30.77 ? 545 PRO A C 1 ATOM 4044 O O . PRO A 1 525 ? -19.021 -36.421 8.559 1.00 31.01 ? 545 PRO A O 1 ATOM 4045 C CB . PRO A 1 525 ? -20.168 -35.591 5.607 1.00 31.38 ? 545 PRO A CB 1 ATOM 4046 C CG . PRO A 1 525 ? -20.541 -34.523 4.666 1.00 31.25 ? 545 PRO A CG 1 ATOM 4047 C CD . PRO A 1 525 ? -19.882 -33.253 5.104 1.00 30.70 ? 545 PRO A CD 1 ATOM 4048 N N . ARG A 1 526 ? -17.472 -35.380 7.305 1.00 30.54 ? 546 ARG A N 1 ATOM 4049 C CA . ARG A 1 526 ? -16.333 -36.045 7.954 1.00 30.13 ? 546 ARG A CA 1 ATOM 4050 C C . ARG A 1 526 ? -16.102 -35.583 9.388 1.00 29.85 ? 546 ARG A C 1 ATOM 4051 O O . ARG A 1 526 ? -15.209 -36.097 10.063 1.00 29.76 ? 546 ARG A O 1 ATOM 4052 C CB . ARG A 1 526 ? -15.042 -35.828 7.152 1.00 30.30 ? 546 ARG A CB 1 ATOM 4053 C CG . ARG A 1 526 ? -15.040 -36.486 5.767 1.00 30.54 ? 546 ARG A CG 1 ATOM 4054 C CD . ARG A 1 526 ? -13.676 -36.358 5.086 1.00 30.46 ? 546 ARG A CD 1 ATOM 4055 N N . HIS A 1 527 ? -16.900 -34.625 9.863 1.00 29.27 ? 547 HIS A N 1 ATOM 4056 C CA . HIS A 1 527 ? -16.648 -33.999 11.155 1.00 28.56 ? 547 HIS A CA 1 ATOM 4057 C C . HIS A 1 527 ? -17.830 -34.049 12.099 1.00 27.99 ? 547 HIS A C 1 ATOM 4058 O O . HIS A 1 527 ? -18.953 -34.331 11.692 1.00 27.49 ? 547 HIS A O 1 ATOM 4059 C CB . HIS A 1 527 ? -16.223 -32.557 10.935 1.00 28.66 ? 547 HIS A CB 1 ATOM 4060 C CG . HIS A 1 527 ? -14.997 -32.427 10.097 1.00 28.94 ? 547 HIS A CG 1 ATOM 4061 N ND1 . HIS A 1 527 ? -15.047 -32.193 8.740 1.00 28.06 ? 547 HIS A ND1 1 ATOM 4062 C CD2 . HIS A 1 527 ? -13.686 -32.538 10.415 1.00 28.97 ? 547 HIS A CD2 1 ATOM 4063 C CE1 . HIS A 1 527 ? -13.817 -32.147 8.263 1.00 28.13 ? 547 HIS A CE1 1 ATOM 4064 N NE2 . HIS A 1 527 ? -12.974 -32.360 9.257 1.00 28.32 ? 547 HIS A NE2 1 ATOM 4065 N N . ARG A 1 528 ? -17.546 -33.766 13.371 1.00 27.72 ? 548 ARG A N 1 ATOM 4066 C CA . ARG A 1 528 ? -18.559 -33.744 14.422 1.00 27.37 ? 548 ARG A CA 1 ATOM 4067 C C . ARG A 1 528 ? -18.800 -32.319 14.912 1.00 26.76 ? 548 ARG A C 1 ATOM 4068 O O . ARG A 1 528 ? -17.893 -31.496 14.933 1.00 26.71 ? 548 ARG A O 1 ATOM 4069 C CB . ARG A 1 528 ? -18.128 -34.580 15.634 1.00 27.61 ? 548 ARG A CB 1 ATOM 4070 C CG . ARG A 1 528 ? -17.607 -35.972 15.350 1.00 27.38 ? 548 ARG A CG 1 ATOM 4071 C CD . ARG A 1 528 ? -18.614 -36.822 14.658 1.00 27.73 ? 548 ARG A CD 1 ATOM 4072 N NE . ARG A 1 528 ? -19.804 -37.047 15.469 1.00 28.62 ? 548 ARG A NE 1 ATOM 4073 C CZ . ARG A 1 528 ? -20.887 -37.687 15.040 1.00 28.98 ? 548 ARG A CZ 1 ATOM 4074 N NH1 . ARG A 1 528 ? -20.929 -38.182 13.810 1.00 29.33 ? 548 ARG A NH1 1 ATOM 4075 N NH2 . ARG A 1 528 ? -21.935 -37.840 15.845 1.00 29.83 ? 548 ARG A NH2 1 ATOM 4076 N N . VAL A 1 529 ? -20.032 -32.053 15.324 1.00 26.14 ? 549 VAL A N 1 ATOM 4077 C CA . VAL A 1 529 ? -20.350 -30.866 16.104 1.00 25.52 ? 549 VAL A CA 1 ATOM 4078 C C . VAL A 1 529 ? -20.761 -31.322 17.498 1.00 25.22 ? 549 VAL A C 1 ATOM 4079 O O . VAL A 1 529 ? -21.782 -32.000 17.657 1.00 25.27 ? 549 VAL A O 1 ATOM 4080 C CB . VAL A 1 529 ? -21.489 -30.059 15.447 1.00 25.67 ? 549 VAL A CB 1 ATOM 4081 C CG1 . VAL A 1 529 ? -22.103 -29.066 16.444 1.00 24.69 ? 549 VAL A CG1 1 ATOM 4082 C CG2 . VAL A 1 529 ? -20.968 -29.352 14.180 1.00 24.26 ? 549 VAL A CG2 1 ATOM 4083 N N . VAL A 1 530 ? -19.956 -30.976 18.499 1.00 24.69 ? 550 VAL A N 1 ATOM 4084 C CA . VAL A 1 530 ? -20.322 -31.205 19.901 1.00 24.29 ? 550 VAL A CA 1 ATOM 4085 C C . VAL A 1 530 ? -20.767 -29.869 20.480 1.00 23.82 ? 550 VAL A C 1 ATOM 4086 O O . VAL A 1 530 ? -19.960 -28.951 20.590 1.00 23.42 ? 550 VAL A O 1 ATOM 4087 C CB . VAL A 1 530 ? -19.146 -31.764 20.725 1.00 24.34 ? 550 VAL A CB 1 ATOM 4088 C CG1 . VAL A 1 530 ? -19.534 -31.881 22.192 1.00 23.36 ? 550 VAL A CG1 1 ATOM 4089 C CG2 . VAL A 1 530 ? -18.705 -33.133 20.171 1.00 24.93 ? 550 VAL A CG2 1 ATOM 4090 N N . GLN A 1 531 ? -22.044 -29.751 20.836 1.00 23.33 ? 551 GLN A N 1 ATOM 4091 C CA . GLN A 1 531 ? -22.604 -28.435 21.162 1.00 23.36 ? 551 GLN A CA 1 ATOM 4092 C C . GLN A 1 531 ? -23.755 -28.453 22.173 1.00 23.27 ? 551 GLN A C 1 ATOM 4093 O O . GLN A 1 531 ? -24.443 -29.479 22.332 1.00 23.03 ? 551 GLN A O 1 ATOM 4094 C CB . GLN A 1 531 ? -23.097 -27.752 19.890 1.00 23.43 ? 551 GLN A CB 1 ATOM 4095 C CG . GLN A 1 531 ? -24.377 -28.386 19.312 1.00 24.03 ? 551 GLN A CG 1 ATOM 4096 C CD . GLN A 1 531 ? -25.091 -27.475 18.362 1.00 23.85 ? 551 GLN A CD 1 ATOM 4097 O OE1 . GLN A 1 531 ? -24.811 -26.284 18.318 1.00 25.10 ? 551 GLN A OE1 1 ATOM 4098 N NE2 . GLN A 1 531 ? -26.035 -28.023 17.599 1.00 24.15 ? 551 GLN A NE2 1 ATOM 4099 N N . PRO A 1 532 ? -23.972 -27.306 22.842 1.00 22.68 ? 552 PRO A N 1 ATOM 4100 C CA . PRO A 1 532 ? -25.069 -27.141 23.790 1.00 22.84 ? 552 PRO A CA 1 ATOM 4101 C C . PRO A 1 532 ? -26.440 -27.369 23.182 1.00 22.43 ? 552 PRO A C 1 ATOM 4102 O O . PRO A 1 532 ? -26.697 -26.975 22.043 1.00 21.83 ? 552 PRO A O 1 ATOM 4103 C CB . PRO A 1 532 ? -24.954 -25.667 24.204 1.00 22.70 ? 552 PRO A CB 1 ATOM 4104 C CG . PRO A 1 532 ? -23.536 -25.353 24.054 1.00 22.88 ? 552 PRO A CG 1 ATOM 4105 C CD . PRO A 1 532 ? -23.080 -26.133 22.850 1.00 22.81 ? 552 PRO A CD 1 ATOM 4106 N N . THR A 1 533 ? -27.301 -28.007 23.956 1.00 22.57 ? 553 THR A N 1 ATOM 4107 C CA . THR A 1 533 ? -28.729 -28.003 23.695 1.00 22.55 ? 553 THR A CA 1 ATOM 4108 C C . THR A 1 533 ? -29.445 -27.599 24.972 1.00 22.91 ? 553 THR A C 1 ATOM 4109 O O . THR A 1 533 ? -28.859 -27.620 26.050 1.00 22.32 ? 553 THR A O 1 ATOM 4110 C CB . THR A 1 533 ? -29.216 -29.381 23.257 1.00 22.74 ? 553 THR A CB 1 ATOM 4111 O OG1 . THR A 1 533 ? -29.178 -30.284 24.372 1.00 21.85 ? 553 THR A OG1 1 ATOM 4112 C CG2 . THR A 1 533 ? -28.339 -29.923 22.110 1.00 22.36 ? 553 THR A CG2 1 ATOM 4113 N N . LEU A 1 534 ? -30.713 -27.227 24.832 1.00 23.65 ? 554 LEU A N 1 ATOM 4114 C CA . LEU A 1 534 ? -31.548 -26.808 25.946 1.00 24.72 ? 554 LEU A CA 1 ATOM 4115 C C . LEU A 1 534 ? -32.366 -28.015 26.385 1.00 25.26 ? 554 LEU A C 1 ATOM 4116 O O . LEU A 1 534 ? -33.140 -28.548 25.595 1.00 25.74 ? 554 LEU A O 1 ATOM 4117 C CB . LEU A 1 534 ? -32.471 -25.660 25.500 1.00 24.98 ? 554 LEU A CB 1 ATOM 4118 C CG . LEU A 1 534 ? -33.582 -25.148 26.420 1.00 25.91 ? 554 LEU A CG 1 ATOM 4119 C CD1 . LEU A 1 534 ? -33.046 -24.807 27.774 1.00 27.28 ? 554 LEU A CD1 1 ATOM 4120 C CD2 . LEU A 1 534 ? -34.237 -23.921 25.808 1.00 27.52 ? 554 LEU A CD2 1 ATOM 4121 N N . GLU A 1 535 ? -32.186 -28.436 27.636 1.00 25.77 ? 555 GLU A N 1 ATOM 4122 C CA . GLU A 1 535 ? -32.946 -29.538 28.249 1.00 26.22 ? 555 GLU A CA 1 ATOM 4123 C C . GLU A 1 535 ? -33.933 -28.999 29.296 1.00 26.02 ? 555 GLU A C 1 ATOM 4124 O O . GLU A 1 535 ? -33.522 -28.285 30.217 1.00 25.52 ? 555 GLU A O 1 ATOM 4125 C CB . GLU A 1 535 ? -31.964 -30.480 28.939 1.00 26.97 ? 555 GLU A CB 1 ATOM 4126 C CG . GLU A 1 535 ? -32.552 -31.741 29.546 1.00 29.19 ? 555 GLU A CG 1 ATOM 4127 C CD . GLU A 1 535 ? -31.510 -32.512 30.349 1.00 32.00 ? 555 GLU A CD 1 ATOM 4128 O OE1 . GLU A 1 535 ? -31.060 -33.581 29.871 1.00 35.20 ? 555 GLU A OE1 1 ATOM 4129 O OE2 . GLU A 1 535 ? -31.123 -32.035 31.442 1.00 31.99 ? 555 GLU A OE2 1 ATOM 4130 N N . GLN A 1 536 ? -35.213 -29.350 29.151 1.00 25.63 ? 556 GLN A N 1 ATOM 4131 C CA . GLN A 1 536 ? -36.256 -29.038 30.135 1.00 25.83 ? 556 GLN A CA 1 ATOM 4132 C C . GLN A 1 536 ? -36.523 -30.255 31.017 1.00 25.16 ? 556 GLN A C 1 ATOM 4133 O O . GLN A 1 536 ? -36.626 -31.371 30.515 1.00 25.29 ? 556 GLN A O 1 ATOM 4134 C CB . GLN A 1 536 ? -37.591 -28.715 29.451 1.00 26.64 ? 556 GLN A CB 1 ATOM 4135 C CG . GLN A 1 536 ? -37.635 -27.488 28.573 1.00 29.24 ? 556 GLN A CG 1 ATOM 4136 C CD . GLN A 1 536 ? -39.070 -26.978 28.345 1.00 33.37 ? 556 GLN A CD 1 ATOM 4137 O OE1 . GLN A 1 536 ? -39.935 -27.075 29.231 1.00 36.10 ? 556 GLN A OE1 1 ATOM 4138 N NE2 . GLN A 1 536 ? -39.317 -26.420 27.163 1.00 34.47 ? 556 GLN A NE2 1 ATOM 4139 N N . THR A 1 537 ? -36.660 -30.041 32.321 1.00 24.36 ? 557 THR A N 1 ATOM 4140 C CA . THR A 1 537 ? -37.120 -31.086 33.229 1.00 23.72 ? 557 THR A CA 1 ATOM 4141 C C . THR A 1 537 ? -38.379 -30.624 33.951 1.00 23.51 ? 557 THR A C 1 ATOM 4142 O O . THR A 1 537 ? -38.398 -29.554 34.554 1.00 23.41 ? 557 THR A O 1 ATOM 4143 C CB . THR A 1 537 ? -36.060 -31.443 34.267 1.00 23.83 ? 557 THR A CB 1 ATOM 4144 O OG1 . THR A 1 537 ? -34.836 -31.773 33.607 1.00 22.80 ? 557 THR A OG1 1 ATOM 4145 C CG2 . THR A 1 537 ? -36.530 -32.617 35.131 1.00 22.41 ? 557 THR A CG2 1 ATOM 4146 N N . GLN A 1 538 ? -39.422 -31.440 33.881 1.00 23.25 ? 558 GLN A N 1 ATOM 4147 C CA . GLN A 1 538 ? -40.676 -31.180 34.575 1.00 23.43 ? 558 GLN A CA 1 ATOM 4148 C C . GLN A 1 538 ? -40.666 -31.900 35.916 1.00 22.60 ? 558 GLN A C 1 ATOM 4149 O O . GLN A 1 538 ? -39.959 -32.878 36.086 1.00 23.22 ? 558 GLN A O 1 ATOM 4150 C CB . GLN A 1 538 ? -41.861 -31.659 33.741 1.00 23.74 ? 558 GLN A CB 1 ATOM 4151 C CG . GLN A 1 538 ? -41.815 -31.229 32.296 1.00 26.04 ? 558 GLN A CG 1 ATOM 4152 C CD . GLN A 1 538 ? -41.557 -29.745 32.149 1.00 29.02 ? 558 GLN A CD 1 ATOM 4153 O OE1 . GLN A 1 538 ? -42.132 -28.930 32.877 1.00 33.20 ? 558 GLN A OE1 1 ATOM 4154 N NE2 . GLN A 1 538 ? -40.681 -29.384 31.220 1.00 30.90 ? 558 GLN A NE2 1 ATOM 4155 N N . TYR A 1 539 ? -41.431 -31.384 36.865 1.00 21.76 ? 559 TYR A N 1 ATOM 4156 C CA . TYR A 1 539 ? -41.498 -31.924 38.218 1.00 20.86 ? 559 TYR A CA 1 ATOM 4157 C C . TYR A 1 539 ? -42.968 -32.101 38.551 1.00 21.04 ? 559 TYR A C 1 ATOM 4158 O O . TYR A 1 539 ? -43.755 -31.170 38.375 1.00 20.87 ? 559 TYR A O 1 ATOM 4159 C CB . TYR A 1 539 ? -40.824 -30.969 39.210 1.00 20.32 ? 559 TYR A CB 1 ATOM 4160 C CG . TYR A 1 539 ? -39.328 -30.829 38.985 1.00 18.48 ? 559 TYR A CG 1 ATOM 4161 C CD1 . TYR A 1 539 ? -38.836 -30.117 37.901 1.00 16.97 ? 559 TYR A CD1 1 ATOM 4162 C CD2 . TYR A 1 539 ? -38.415 -31.412 39.845 1.00 16.92 ? 559 TYR A CD2 1 ATOM 4163 C CE1 . TYR A 1 539 ? -37.480 -29.999 37.674 1.00 17.46 ? 559 TYR A CE1 1 ATOM 4164 C CE2 . TYR A 1 539 ? -37.044 -31.302 39.625 1.00 17.06 ? 559 TYR A CE2 1 ATOM 4165 C CZ . TYR A 1 539 ? -36.587 -30.596 38.531 1.00 16.91 ? 559 TYR A CZ 1 ATOM 4166 O OH . TYR A 1 539 ? -35.235 -30.467 38.296 1.00 17.85 ? 559 TYR A OH 1 ATOM 4167 N N . SER A 1 540 ? -43.342 -33.297 39.006 1.00 21.07 ? 560 SER A N 1 ATOM 4168 C CA . SER A 1 540 ? -44.742 -33.613 39.294 1.00 21.04 ? 560 SER A CA 1 ATOM 4169 C C . SER A 1 540 ? -45.050 -33.775 40.779 1.00 20.20 ? 560 SER A C 1 ATOM 4170 O O . SER A 1 540 ? -46.197 -33.673 41.171 1.00 19.89 ? 560 SER A O 1 ATOM 4171 C CB . SER A 1 540 ? -45.143 -34.900 38.569 1.00 21.50 ? 560 SER A CB 1 ATOM 4172 O OG . SER A 1 540 ? -45.307 -34.659 37.186 1.00 23.32 ? 560 SER A OG 1 ATOM 4173 N N . TRP A 1 541 ? -44.041 -34.054 41.599 1.00 20.21 ? 561 TRP A N 1 ATOM 4174 C CA . TRP A 1 541 ? -44.270 -34.359 43.019 1.00 19.76 ? 561 TRP A CA 1 ATOM 4175 C C . TRP A 1 541 ? -43.309 -33.608 43.925 1.00 19.54 ? 561 TRP A C 1 ATOM 4176 O O . TRP A 1 541 ? -42.152 -33.386 43.571 1.00 20.08 ? 561 TRP A O 1 ATOM 4177 C CB . TRP A 1 541 ? -44.162 -35.862 43.251 1.00 19.60 ? 561 TRP A CB 1 ATOM 4178 C CG . TRP A 1 541 ? -44.969 -36.663 42.275 1.00 19.50 ? 561 TRP A CG 1 ATOM 4179 C CD1 . TRP A 1 541 ? -44.542 -37.166 41.082 1.00 19.33 ? 561 TRP A CD1 1 ATOM 4180 C CD2 . TRP A 1 541 ? -46.344 -37.049 42.407 1.00 18.19 ? 561 TRP A CD2 1 ATOM 4181 N NE1 . TRP A 1 541 ? -45.568 -37.835 40.460 1.00 19.64 ? 561 TRP A NE1 1 ATOM 4182 C CE2 . TRP A 1 541 ? -46.687 -37.771 41.245 1.00 18.83 ? 561 TRP A CE2 1 ATOM 4183 C CE3 . TRP A 1 541 ? -47.322 -36.848 43.389 1.00 17.84 ? 561 TRP A CE3 1 ATOM 4184 C CZ2 . TRP A 1 541 ? -47.966 -38.313 41.045 1.00 18.53 ? 561 TRP A CZ2 1 ATOM 4185 C CZ3 . TRP A 1 541 ? -48.597 -37.377 43.184 1.00 17.46 ? 561 TRP A CZ3 1 ATOM 4186 C CH2 . TRP A 1 541 ? -48.903 -38.101 42.023 1.00 16.51 ? 561 TRP A CH2 1 ATOM 4187 N N . GLU A 1 542 ? -43.788 -33.219 45.103 1.00 19.47 ? 562 GLU A N 1 ATOM 4188 C CA . GLU A 1 542 ? -42.990 -32.392 46.012 1.00 19.17 ? 562 GLU A CA 1 ATOM 4189 C C . GLU A 1 542 ? -41.573 -32.917 46.194 1.00 19.29 ? 562 GLU A C 1 ATOM 4190 O O . GLU A 1 542 ? -40.620 -32.153 46.097 1.00 19.85 ? 562 GLU A O 1 ATOM 4191 C CB . GLU A 1 542 ? -43.668 -32.271 47.374 1.00 19.03 ? 562 GLU A CB 1 ATOM 4192 C CG . GLU A 1 542 ? -44.927 -31.416 47.362 1.00 19.33 ? 562 GLU A CG 1 ATOM 4193 C CD . GLU A 1 542 ? -45.624 -31.396 48.700 1.00 19.62 ? 562 GLU A CD 1 ATOM 4194 O OE1 . GLU A 1 542 ? -45.775 -32.485 49.315 1.00 17.70 ? 562 GLU A OE1 1 ATOM 4195 O OE2 . GLU A 1 542 ? -46.026 -30.291 49.146 1.00 18.53 ? 562 GLU A OE2 1 ATOM 4196 N N . ARG A 1 543 ? -41.433 -34.222 46.427 1.00 19.51 ? 563 ARG A N 1 ATOM 4197 C CA A ARG A 1 543 ? -40.132 -34.821 46.729 0.60 19.67 ? 563 ARG A CA 1 ATOM 4198 C CA B ARG A 1 543 ? -40.131 -34.802 46.733 0.40 19.55 ? 563 ARG A CA 1 ATOM 4199 C C . ARG A 1 543 ? -39.136 -34.623 45.587 1.00 19.87 ? 563 ARG A C 1 ATOM 4200 O O . ARG A 1 543 ? -37.941 -34.505 45.820 1.00 20.06 ? 563 ARG A O 1 ATOM 4201 C CB A ARG A 1 543 ? -40.262 -36.320 47.043 0.60 19.59 ? 563 ARG A CB 1 ATOM 4202 C CB B ARG A 1 543 ? -40.277 -36.282 47.091 0.40 19.37 ? 563 ARG A CB 1 ATOM 4203 C CG A ARG A 1 543 ? -40.913 -36.658 48.393 0.60 19.58 ? 563 ARG A CG 1 ATOM 4204 C CG B ARG A 1 543 ? -38.979 -36.965 47.485 0.40 18.83 ? 563 ARG A CG 1 ATOM 4205 C CD A ARG A 1 543 ? -39.998 -36.399 49.588 0.60 19.45 ? 563 ARG A CD 1 ATOM 4206 C CD B ARG A 1 543 ? -38.143 -36.153 48.458 0.40 17.32 ? 563 ARG A CD 1 ATOM 4207 N NE A ARG A 1 543 ? -40.476 -37.076 50.799 0.60 19.75 ? 563 ARG A NE 1 ATOM 4208 N NE B ARG A 1 543 ? -38.695 -36.153 49.808 0.40 16.09 ? 563 ARG A NE 1 ATOM 4209 C CZ A ARG A 1 543 ? -39.893 -37.011 52.000 0.60 19.14 ? 563 ARG A CZ 1 ATOM 4210 C CZ B ARG A 1 543 ? -38.158 -35.494 50.832 0.40 14.32 ? 563 ARG A CZ 1 ATOM 4211 N NH1 A ARG A 1 543 ? -38.797 -36.287 52.194 0.60 18.83 ? 563 ARG A NH1 1 ATOM 4212 N NH1 B ARG A 1 543 ? -37.045 -34.786 50.664 0.40 11.79 ? 563 ARG A NH1 1 ATOM 4213 N NH2 A ARG A 1 543 ? -40.413 -37.677 53.025 0.60 20.15 ? 563 ARG A NH2 1 ATOM 4214 N NH2 B ARG A 1 543 ? -38.733 -35.550 52.026 0.40 14.91 ? 563 ARG A NH2 1 ATOM 4215 N N . GLN A 1 544 ? -39.630 -34.592 44.352 1.00 20.17 ? 564 GLN A N 1 ATOM 4216 C CA . GLN A 1 544 ? -38.754 -34.376 43.206 1.00 20.69 ? 564 GLN A CA 1 ATOM 4217 C C . GLN A 1 544 ? -38.169 -32.957 43.212 1.00 20.88 ? 564 GLN A C 1 ATOM 4218 O O . GLN A 1 544 ? -37.070 -32.734 42.701 1.00 21.24 ? 564 GLN A O 1 ATOM 4219 C CB . GLN A 1 544 ? -39.518 -34.600 41.901 1.00 21.08 ? 564 GLN A CB 1 ATOM 4220 C CG . GLN A 1 544 ? -40.022 -36.017 41.692 1.00 19.73 ? 564 GLN A CG 1 ATOM 4221 C CD . GLN A 1 544 ? -40.938 -36.099 40.495 1.00 19.60 ? 564 GLN A CD 1 ATOM 4222 O OE1 . GLN A 1 544 ? -41.741 -35.198 40.268 1.00 19.06 ? 564 GLN A OE1 1 ATOM 4223 N NE2 . GLN A 1 544 ? -40.821 -37.177 39.716 1.00 17.92 ? 564 GLN A NE2 1 ATOM 4224 N N . ALA A 1 545 ? -38.918 -32.010 43.782 1.00 20.82 ? 565 ALA A N 1 ATOM 4225 C CA . ALA A 1 545 ? -38.526 -30.597 43.808 1.00 20.86 ? 565 ALA A CA 1 ATOM 4226 C C . ALA A 1 545 ? -37.905 -30.188 45.160 1.00 20.95 ? 565 ALA A C 1 ATOM 4227 O O . ALA A 1 545 ? -37.769 -28.990 45.446 1.00 20.57 ? 565 ALA A O 1 ATOM 4228 C CB . ALA A 1 545 ? -39.736 -29.722 43.487 1.00 20.57 ? 565 ALA A CB 1 ATOM 4229 N N . ALA A 1 546 ? -37.536 -31.178 45.976 1.00 21.04 ? 566 ALA A N 1 ATOM 4230 C CA . ALA A 1 546 ? -36.854 -30.942 47.245 1.00 21.46 ? 566 ALA A CA 1 ATOM 4231 C C . ALA A 1 546 ? -35.358 -31.152 47.037 1.00 21.84 ? 566 ALA A C 1 ATOM 4232 O O . ALA A 1 546 ? -34.876 -32.274 47.080 1.00 22.14 ? 566 ALA A O 1 ATOM 4233 C CB . ALA A 1 546 ? -37.377 -31.887 48.327 1.00 21.48 ? 566 ALA A CB 1 ATOM 4234 N N . PHE A 1 547 ? -34.625 -30.070 46.817 1.00 22.20 ? 567 PHE A N 1 ATOM 4235 C CA . PHE A 1 547 ? -33.212 -30.167 46.466 1.00 22.60 ? 567 PHE A CA 1 ATOM 4236 C C . PHE A 1 547 ? -32.368 -30.115 47.715 1.00 23.97 ? 567 PHE A C 1 ATOM 4237 O O . PHE A 1 547 ? -32.383 -29.117 48.421 1.00 24.20 ? 567 PHE A O 1 ATOM 4238 C CB . PHE A 1 547 ? -32.819 -29.026 45.522 1.00 22.32 ? 567 PHE A CB 1 ATOM 4239 C CG . PHE A 1 547 ? -33.501 -29.089 44.192 1.00 20.31 ? 567 PHE A CG 1 ATOM 4240 C CD1 . PHE A 1 547 ? -32.909 -29.754 43.126 1.00 20.78 ? 567 PHE A CD1 1 ATOM 4241 C CD2 . PHE A 1 547 ? -34.749 -28.521 44.014 1.00 19.12 ? 567 PHE A CD2 1 ATOM 4242 C CE1 . PHE A 1 547 ? -33.551 -29.839 41.893 1.00 19.84 ? 567 PHE A CE1 1 ATOM 4243 C CE2 . PHE A 1 547 ? -35.396 -28.591 42.793 1.00 18.97 ? 567 PHE A CE2 1 ATOM 4244 C CZ . PHE A 1 547 ? -34.795 -29.250 41.727 1.00 18.92 ? 567 PHE A CZ 1 ATOM 4245 N N . ARG A 1 548 ? -31.639 -31.188 47.992 1.00 25.52 ? 568 ARG A N 1 ATOM 4246 C CA . ARG A 1 548 ? -30.723 -31.220 49.129 1.00 27.17 ? 568 ARG A CA 1 ATOM 4247 C C . ARG A 1 548 ? -29.415 -30.563 48.721 1.00 27.98 ? 568 ARG A C 1 ATOM 4248 O O . ARG A 1 548 ? -29.177 -30.338 47.538 1.00 28.06 ? 568 ARG A O 1 ATOM 4249 C CB . ARG A 1 548 ? -30.479 -32.655 49.597 1.00 27.31 ? 568 ARG A CB 1 ATOM 4250 C CG . ARG A 1 548 ? -31.711 -33.335 50.177 1.00 28.06 ? 568 ARG A CG 1 ATOM 4251 C CD . ARG A 1 548 ? -31.532 -34.856 50.242 1.00 29.83 ? 568 ARG A CD 1 ATOM 4252 N N . PHE A 1 549 ? -28.578 -30.250 49.702 1.00 29.29 ? 569 PHE A N 1 ATOM 4253 C CA . PHE A 1 549 ? -27.305 -29.583 49.443 1.00 30.53 ? 569 PHE A CA 1 ATOM 4254 C C . PHE A 1 549 ? -26.320 -30.468 48.675 1.00 31.86 ? 569 PHE A C 1 ATOM 4255 O O . PHE A 1 549 ? -25.459 -29.956 47.968 1.00 32.44 ? 569 PHE A O 1 ATOM 4256 C CB . PHE A 1 549 ? -26.661 -29.085 50.750 1.00 30.58 ? 569 PHE A CB 1 ATOM 4257 C CG . PHE A 1 549 ? -27.201 -27.767 51.221 1.00 30.62 ? 569 PHE A CG 1 ATOM 4258 C CD1 . PHE A 1 549 ? -28.086 -27.696 52.286 1.00 30.58 ? 569 PHE A CD1 1 ATOM 4259 C CD2 . PHE A 1 549 ? -26.844 -26.591 50.570 1.00 30.69 ? 569 PHE A CD2 1 ATOM 4260 C CE1 . PHE A 1 549 ? -28.598 -26.468 52.706 1.00 30.78 ? 569 PHE A CE1 1 ATOM 4261 C CE2 . PHE A 1 549 ? -27.345 -25.362 50.992 1.00 30.86 ? 569 PHE A CE2 1 ATOM 4262 C CZ . PHE A 1 549 ? -28.226 -25.304 52.060 1.00 30.97 ? 569 PHE A CZ 1 ATOM 4263 N N . LYS A 1 550 ? -26.433 -31.784 48.825 1.00 33.31 ? 570 LYS A N 1 ATOM 4264 C CA . LYS A 1 550 ? -25.594 -32.721 48.062 1.00 34.43 ? 570 LYS A CA 1 ATOM 4265 C C . LYS A 1 550 ? -25.975 -32.718 46.582 1.00 35.08 ? 570 LYS A C 1 ATOM 4266 O O . LYS A 1 550 ? -25.109 -32.781 45.715 1.00 36.14 ? 570 LYS A O 1 ATOM 4267 C CB . LYS A 1 550 ? -25.727 -34.142 48.620 1.00 34.45 ? 570 LYS A CB 1 ATOM 4268 N N . ARG A 1 551 ? -27.275 -32.628 46.306 1.00 35.47 ? 571 ARG A N 1 ATOM 4269 C CA . ARG A 1 551 ? -27.807 -32.645 44.938 1.00 35.42 ? 571 ARG A CA 1 ATOM 4270 C C . ARG A 1 551 ? -27.319 -31.449 44.113 1.00 35.06 ? 571 ARG A C 1 ATOM 4271 O O . ARG A 1 551 ? -27.117 -30.338 44.648 1.00 35.27 ? 571 ARG A O 1 ATOM 4272 C CB . ARG A 1 551 ? -29.345 -32.645 44.991 1.00 35.81 ? 571 ARG A CB 1 ATOM 4273 C CG . ARG A 1 551 ? -30.081 -32.993 43.674 1.00 36.86 ? 571 ARG A CG 1 ATOM 4274 C CD . ARG A 1 551 ? -31.568 -33.197 43.982 1.00 37.69 ? 571 ARG A CD 1 ATOM 4275 N NE . ARG A 1 551 ? -32.425 -33.482 42.829 1.00 37.52 ? 571 ARG A NE 1 ATOM 4276 C CZ . ARG A 1 551 ? -33.755 -33.589 42.899 1.00 37.85 ? 571 ARG A CZ 1 ATOM 4277 N NH1 . ARG A 1 551 ? -34.380 -33.421 44.059 1.00 38.77 ? 571 ARG A NH1 1 ATOM 4278 N NH2 . ARG A 1 551 ? -34.473 -33.851 41.810 1.00 37.76 ? 571 ARG A NH2 1 ATOM 4279 N N . LYS A 1 552 ? -27.125 -31.682 42.813 1.00 33.95 ? 572 LYS A N 1 ATOM 4280 C CA . LYS A 1 552 ? -26.789 -30.610 41.870 1.00 32.97 ? 572 LYS A CA 1 ATOM 4281 C C . LYS A 1 552 ? -28.018 -29.719 41.675 1.00 31.58 ? 572 LYS A C 1 ATOM 4282 O O . LYS A 1 552 ? -29.093 -30.218 41.334 1.00 31.92 ? 572 LYS A O 1 ATOM 4283 C CB . LYS A 1 552 ? -26.349 -31.198 40.521 1.00 32.99 ? 572 LYS A CB 1 ATOM 4284 N N . LEU A 1 553 ? -27.866 -28.415 41.919 1.00 29.99 ? 573 LEU A N 1 ATOM 4285 C CA . LEU A 1 553 ? -28.983 -27.464 41.803 1.00 28.19 ? 573 LEU A CA 1 ATOM 4286 C C . LEU A 1 553 ? -28.979 -26.924 40.374 1.00 26.68 ? 573 LEU A C 1 ATOM 4287 O O . LEU A 1 553 ? -28.006 -26.310 39.963 1.00 25.82 ? 573 LEU A O 1 ATOM 4288 C CB . LEU A 1 553 ? -28.835 -26.324 42.828 1.00 28.16 ? 573 LEU A CB 1 ATOM 4289 C CG . LEU A 1 553 ? -30.068 -25.516 43.265 1.00 27.11 ? 573 LEU A CG 1 ATOM 4290 C CD1 . LEU A 1 553 ? -31.178 -26.383 43.861 1.00 25.06 ? 573 LEU A CD1 1 ATOM 4291 C CD2 . LEU A 1 553 ? -29.684 -24.435 44.278 1.00 25.82 ? 573 LEU A CD2 1 ATOM 4292 N N . PRO A 1 554 ? -30.056 -27.168 39.605 1.00 25.64 ? 574 PRO A N 1 ATOM 4293 C CA . PRO A 1 554 ? -30.081 -26.661 38.229 1.00 24.81 ? 574 PRO A CA 1 ATOM 4294 C C . PRO A 1 554 ? -29.927 -25.140 38.159 1.00 24.04 ? 574 PRO A C 1 ATOM 4295 O O . PRO A 1 554 ? -30.256 -24.423 39.123 1.00 22.71 ? 574 PRO A O 1 ATOM 4296 C CB . PRO A 1 554 ? -31.454 -27.094 37.711 1.00 24.93 ? 574 PRO A CB 1 ATOM 4297 C CG . PRO A 1 554 ? -31.858 -28.220 38.589 1.00 25.40 ? 574 PRO A CG 1 ATOM 4298 C CD . PRO A 1 554 ? -31.277 -27.930 39.927 1.00 25.54 ? 574 PRO A CD 1 ATOM 4299 N N . LYS A 1 555 ? -29.410 -24.677 37.022 1.00 23.30 ? 575 LYS A N 1 ATOM 4300 C CA . LYS A 1 555 ? -29.093 -23.272 36.812 1.00 22.95 ? 575 LYS A CA 1 ATOM 4301 C C . LYS A 1 555 ? -30.336 -22.448 36.580 1.00 22.16 ? 575 LYS A C 1 ATOM 4302 O O . LYS A 1 555 ? -30.333 -21.252 36.866 1.00 22.75 ? 575 LYS A O 1 ATOM 4303 C CB . LYS A 1 555 ? -28.120 -23.108 35.634 1.00 23.47 ? 575 LYS A CB 1 ATOM 4304 C CG . LYS A 1 555 ? -26.750 -23.770 35.869 1.00 23.37 ? 575 LYS A CG 1 ATOM 4305 N N . TYR A 1 556 ? -31.394 -23.072 36.065 1.00 20.92 ? 576 TYR A N 1 ATOM 4306 C CA . TYR A 1 556 ? -32.684 -22.396 35.895 1.00 20.01 ? 576 TYR A CA 1 ATOM 4307 C C . TYR A 1 556 ? -33.774 -23.084 36.694 1.00 19.21 ? 576 TYR A C 1 ATOM 4308 O O . TYR A 1 556 ? -34.206 -24.192 36.358 1.00 18.86 ? 576 TYR A O 1 ATOM 4309 C CB . TYR A 1 556 ? -33.079 -22.317 34.413 1.00 19.73 ? 576 TYR A CB 1 ATOM 4310 C CG . TYR A 1 556 ? -32.374 -21.196 33.702 1.00 20.43 ? 576 TYR A CG 1 ATOM 4311 C CD1 . TYR A 1 556 ? -31.013 -21.283 33.403 1.00 20.42 ? 576 TYR A CD1 1 ATOM 4312 C CD2 . TYR A 1 556 ? -33.051 -20.024 33.361 1.00 20.14 ? 576 TYR A CD2 1 ATOM 4313 C CE1 . TYR A 1 556 ? -30.358 -20.244 32.759 1.00 19.96 ? 576 TYR A CE1 1 ATOM 4314 C CE2 . TYR A 1 556 ? -32.405 -18.990 32.723 1.00 20.05 ? 576 TYR A CE2 1 ATOM 4315 C CZ . TYR A 1 556 ? -31.055 -19.104 32.423 1.00 19.98 ? 576 TYR A CZ 1 ATOM 4316 O OH . TYR A 1 556 ? -30.401 -18.053 31.803 1.00 20.28 ? 576 TYR A OH 1 ATOM 4317 N N . LEU A 1 557 ? -34.208 -22.413 37.753 1.00 18.32 ? 577 LEU A N 1 ATOM 4318 C CA . LEU A 1 557 ? -35.275 -22.900 38.616 1.00 17.99 ? 577 LEU A CA 1 ATOM 4319 C C . LEU A 1 557 ? -36.492 -22.038 38.307 1.00 17.98 ? 577 LEU A C 1 ATOM 4320 O O . LEU A 1 557 ? -36.545 -20.867 38.694 1.00 18.16 ? 577 LEU A O 1 ATOM 4321 C CB . LEU A 1 557 ? -34.851 -22.793 40.091 1.00 17.57 ? 577 LEU A CB 1 ATOM 4322 C CG . LEU A 1 557 ? -33.461 -23.367 40.439 1.00 17.58 ? 577 LEU A CG 1 ATOM 4323 C CD1 . LEU A 1 557 ? -32.942 -22.858 41.797 1.00 14.81 ? 577 LEU A CD1 1 ATOM 4324 C CD2 . LEU A 1 557 ? -33.469 -24.892 40.423 1.00 14.76 ? 577 LEU A CD2 1 ATOM 4325 N N . LEU A 1 558 ? -37.445 -22.598 37.571 1.00 18.26 ? 578 LEU A N 1 ATOM 4326 C CA . LEU A 1 558 ? -38.559 -21.824 37.030 1.00 18.35 ? 578 LEU A CA 1 ATOM 4327 C C . LEU A 1 558 ? -39.909 -22.187 37.667 1.00 18.41 ? 578 LEU A C 1 ATOM 4328 O O . LEU A 1 558 ? -40.232 -23.374 37.844 1.00 18.10 ? 578 LEU A O 1 ATOM 4329 C CB . LEU A 1 558 ? -38.657 -22.032 35.512 1.00 18.51 ? 578 LEU A CB 1 ATOM 4330 C CG . LEU A 1 558 ? -37.426 -21.690 34.661 1.00 20.24 ? 578 LEU A CG 1 ATOM 4331 C CD1 . LEU A 1 558 ? -37.739 -21.918 33.185 1.00 19.81 ? 578 LEU A CD1 1 ATOM 4332 C CD2 . LEU A 1 558 ? -36.957 -20.258 34.902 1.00 20.15 ? 578 LEU A CD2 1 ATOM 4333 N N . PHE A 1 559 ? -40.682 -21.156 37.997 1.00 17.95 ? 579 PHE A N 1 ATOM 4334 C CA . PHE A 1 559 ? -42.073 -21.313 38.418 1.00 18.05 ? 579 PHE A CA 1 ATOM 4335 C C . PHE A 1 559 ? -42.943 -20.750 37.319 1.00 18.21 ? 579 PHE A C 1 ATOM 4336 O O . PHE A 1 559 ? -42.837 -19.573 36.986 1.00 17.72 ? 579 PHE A O 1 ATOM 4337 C CB . PHE A 1 559 ? -42.297 -20.657 39.773 1.00 17.85 ? 579 PHE A CB 1 ATOM 4338 C CG . PHE A 1 559 ? -41.512 -21.327 40.865 1.00 17.72 ? 579 PHE A CG 1 ATOM 4339 C CD1 . PHE A 1 559 ? -40.158 -21.092 41.000 1.00 17.01 ? 579 PHE A CD1 1 ATOM 4340 C CD2 . PHE A 1 559 ? -42.112 -22.246 41.707 1.00 16.92 ? 579 PHE A CD2 1 ATOM 4341 C CE1 . PHE A 1 559 ? -39.418 -21.743 41.980 1.00 17.18 ? 579 PHE A CE1 1 ATOM 4342 C CE2 . PHE A 1 559 ? -41.388 -22.897 42.669 1.00 16.43 ? 579 PHE A CE2 1 ATOM 4343 C CZ . PHE A 1 559 ? -40.028 -22.648 42.807 1.00 16.12 ? 579 PHE A CZ 1 ATOM 4344 N N . THR A 1 560 ? -43.746 -21.619 36.706 1.00 19.09 ? 580 THR A N 1 ATOM 4345 C CA . THR A 1 560 ? -44.416 -21.297 35.447 1.00 20.12 ? 580 THR A CA 1 ATOM 4346 C C . THR A 1 560 ? -45.934 -21.220 35.567 1.00 20.71 ? 580 THR A C 1 ATOM 4347 O O . THR A 1 560 ? -46.542 -21.870 36.414 1.00 20.37 ? 580 THR A O 1 ATOM 4348 C CB . THR A 1 560 ? -44.088 -22.351 34.372 1.00 20.68 ? 580 THR A CB 1 ATOM 4349 O OG1 . THR A 1 560 ? -44.846 -23.544 34.637 1.00 23.16 ? 580 THR A OG1 1 ATOM 4350 C CG2 . THR A 1 560 ? -42.568 -22.666 34.366 1.00 18.78 ? 580 THR A CG2 1 ATOM 4351 N N . SER A 1 561 ? -46.527 -20.424 34.681 1.00 21.51 ? 581 SER A N 1 ATOM 4352 C CA . SER A 1 561 ? -47.955 -20.381 34.472 1.00 22.13 ? 581 SER A CA 1 ATOM 4353 C C . SER A 1 561 ? -48.276 -21.089 33.162 1.00 23.26 ? 581 SER A C 1 ATOM 4354 O O . SER A 1 561 ? -47.463 -21.068 32.241 1.00 23.46 ? 581 SER A O 1 ATOM 4355 C CB . SER A 1 561 ? -48.413 -18.929 34.372 1.00 22.45 ? 581 SER A CB 1 ATOM 4356 O OG . SER A 1 561 ? -49.800 -18.841 34.101 1.00 22.07 ? 581 SER A OG 1 ATOM 4357 N N . PRO A 1 562 ? -49.476 -21.688 33.045 1.00 24.40 ? 582 PRO A N 1 ATOM 4358 C CA . PRO A 1 562 ? -49.825 -22.290 31.749 1.00 25.31 ? 582 PRO A CA 1 ATOM 4359 C C . PRO A 1 562 ? -49.985 -21.268 30.610 1.00 26.00 ? 582 PRO A C 1 ATOM 4360 O O . PRO A 1 562 ? -49.917 -21.639 29.452 1.00 26.92 ? 582 PRO A O 1 ATOM 4361 C CB . PRO A 1 562 ? -51.150 -23.013 32.035 1.00 25.34 ? 582 PRO A CB 1 ATOM 4362 C CG . PRO A 1 562 ? -51.196 -23.170 33.501 1.00 25.43 ? 582 PRO A CG 1 ATOM 4363 C CD . PRO A 1 562 ? -50.509 -21.948 34.054 1.00 24.13 ? 582 PRO A CD 1 ATOM 4364 N N . GLN A 1 563 ? -50.163 -19.994 30.938 1.00 26.84 ? 583 GLN A N 1 ATOM 4365 C CA . GLN A 1 563 ? -50.237 -18.936 29.925 1.00 27.14 ? 583 GLN A CA 1 ATOM 4366 C C . GLN A 1 563 ? -48.897 -18.786 29.200 1.00 27.02 ? 583 GLN A C 1 ATOM 4367 O O . GLN A 1 563 ? -47.829 -18.862 29.820 1.00 26.03 ? 583 GLN A O 1 ATOM 4368 C CB . GLN A 1 563 ? -50.572 -17.592 30.565 1.00 27.75 ? 583 GLN A CB 1 ATOM 4369 C CG . GLN A 1 563 ? -51.811 -17.559 31.454 1.00 30.24 ? 583 GLN A CG 1 ATOM 4370 C CD . GLN A 1 563 ? -51.936 -16.237 32.187 1.00 33.21 ? 583 GLN A CD 1 ATOM 4371 O OE1 . GLN A 1 563 ? -51.471 -15.199 31.699 1.00 35.83 ? 583 GLN A OE1 1 ATOM 4372 N NE2 . GLN A 1 563 ? -52.539 -16.266 33.372 1.00 34.41 ? 583 GLN A NE2 1 ATOM 4373 N N . GLU A 1 564 ? -48.972 -18.571 27.889 1.00 26.73 ? 584 GLU A N 1 ATOM 4374 C CA . GLU A 1 564 ? -47.798 -18.406 27.044 1.00 26.77 ? 584 GLU A CA 1 ATOM 4375 C C . GLU A 1 564 ? -47.639 -16.933 26.722 1.00 25.55 ? 584 GLU A C 1 ATOM 4376 O O . GLU A 1 564 ? -48.636 -16.210 26.652 1.00 25.66 ? 584 GLU A O 1 ATOM 4377 C CB . GLU A 1 564 ? -47.962 -19.169 25.731 1.00 27.20 ? 584 GLU A CB 1 ATOM 4378 C CG . GLU A 1 564 ? -47.864 -20.685 25.846 1.00 29.98 ? 584 GLU A CG 1 ATOM 4379 C CD . GLU A 1 564 ? -47.958 -21.371 24.493 1.00 32.89 ? 584 GLU A CD 1 ATOM 4380 O OE1 . GLU A 1 564 ? -48.359 -20.711 23.511 1.00 34.80 ? 584 GLU A OE1 1 ATOM 4381 O OE2 . GLU A 1 564 ? -47.615 -22.567 24.401 1.00 37.00 ? 584 GLU A OE2 1 ATOM 4382 N N . ASN A 1 565 ? -46.395 -16.492 26.519 1.00 23.90 ? 585 ASN A N 1 ATOM 4383 C CA . ASN A 1 565 ? -46.137 -15.151 25.990 1.00 22.54 ? 585 ASN A CA 1 ATOM 4384 C C . ASN A 1 565 ? -46.416 -15.170 24.484 1.00 22.28 ? 585 ASN A C 1 ATOM 4385 O O . ASN A 1 565 ? -46.739 -16.227 23.952 1.00 21.82 ? 585 ASN A O 1 ATOM 4386 C CB . ASN A 1 565 ? -44.726 -14.668 26.364 1.00 22.37 ? 585 ASN A CB 1 ATOM 4387 C CG . ASN A 1 565 ? -43.606 -15.349 25.581 1.00 21.36 ? 585 ASN A CG 1 ATOM 4388 O OD1 . ASN A 1 565 ? -43.833 -16.156 24.680 1.00 19.39 ? 585 ASN A OD1 1 ATOM 4389 N ND2 . ASN A 1 565 ? -42.368 -15.013 25.941 1.00 18.89 ? 585 ASN A ND2 1 ATOM 4390 N N . PRO A 1 566 ? -46.317 -14.015 23.794 1.00 21.67 ? 586 PRO A N 1 ATOM 4391 C CA . PRO A 1 566 ? -46.590 -13.986 22.351 1.00 21.48 ? 586 PRO A CA 1 ATOM 4392 C C . PRO A 1 566 ? -45.688 -14.850 21.470 1.00 21.31 ? 586 PRO A C 1 ATOM 4393 O O . PRO A 1 566 ? -46.002 -15.052 20.300 1.00 21.39 ? 586 PRO A O 1 ATOM 4394 C CB . PRO A 1 566 ? -46.397 -12.505 21.991 1.00 21.81 ? 586 PRO A CB 1 ATOM 4395 C CG . PRO A 1 566 ? -46.707 -11.787 23.250 1.00 22.14 ? 586 PRO A CG 1 ATOM 4396 C CD . PRO A 1 566 ? -46.137 -12.657 24.329 1.00 21.74 ? 586 PRO A CD 1 ATOM 4397 N N . TRP A 1 567 ? -44.590 -15.364 22.017 1.00 21.21 ? 587 TRP A N 1 ATOM 4398 C CA . TRP A 1 567 ? -43.627 -16.135 21.241 1.00 20.68 ? 587 TRP A CA 1 ATOM 4399 C C . TRP A 1 567 ? -43.737 -17.636 21.519 1.00 20.62 ? 587 TRP A C 1 ATOM 4400 O O . TRP A 1 567 ? -42.870 -18.402 21.114 1.00 20.65 ? 587 TRP A O 1 ATOM 4401 C CB . TRP A 1 567 ? -42.223 -15.622 21.539 1.00 20.61 ? 587 TRP A CB 1 ATOM 4402 C CG . TRP A 1 567 ? -42.219 -14.140 21.647 1.00 20.78 ? 587 TRP A CG 1 ATOM 4403 C CD1 . TRP A 1 567 ? -41.888 -13.395 22.739 1.00 20.55 ? 587 TRP A CD1 1 ATOM 4404 C CD2 . TRP A 1 567 ? -42.633 -13.214 20.637 1.00 20.17 ? 587 TRP A CD2 1 ATOM 4405 N NE1 . TRP A 1 567 ? -42.044 -12.059 22.461 1.00 20.80 ? 587 TRP A NE1 1 ATOM 4406 C CE2 . TRP A 1 567 ? -42.501 -11.924 21.176 1.00 20.14 ? 587 TRP A CE2 1 ATOM 4407 C CE3 . TRP A 1 567 ? -43.080 -13.355 19.316 1.00 20.20 ? 587 TRP A CE3 1 ATOM 4408 C CZ2 . TRP A 1 567 ? -42.812 -10.776 20.447 1.00 21.52 ? 587 TRP A CZ2 1 ATOM 4409 C CZ3 . TRP A 1 567 ? -43.387 -12.216 18.590 1.00 20.25 ? 587 TRP A CZ3 1 ATOM 4410 C CH2 . TRP A 1 567 ? -43.255 -10.943 19.156 1.00 21.54 ? 587 TRP A CH2 1 ATOM 4411 N N . GLY A 1 568 ? -44.800 -18.047 22.213 1.00 20.41 ? 588 GLY A N 1 ATOM 4412 C CA . GLY A 1 568 ? -45.080 -19.468 22.450 1.00 20.48 ? 588 GLY A CA 1 ATOM 4413 C C . GLY A 1 568 ? -44.411 -20.071 23.679 1.00 20.46 ? 588 GLY A C 1 ATOM 4414 O O . GLY A 1 568 ? -44.418 -21.297 23.859 1.00 21.49 ? 588 GLY A O 1 ATOM 4415 N N . HIS A 1 569 ? -43.839 -19.231 24.536 1.00 20.10 ? 589 HIS A N 1 ATOM 4416 C CA . HIS A 1 569 ? -43.146 -19.720 25.728 1.00 19.51 ? 589 HIS A CA 1 ATOM 4417 C C . HIS A 1 569 ? -43.940 -19.415 26.975 1.00 19.70 ? 589 HIS A C 1 ATOM 4418 O O . HIS A 1 569 ? -44.528 -18.341 27.092 1.00 19.40 ? 589 HIS A O 1 ATOM 4419 C CB . HIS A 1 569 ? -41.755 -19.111 25.819 1.00 19.25 ? 589 HIS A CB 1 ATOM 4420 C CG . HIS A 1 569 ? -40.825 -19.625 24.772 1.00 18.30 ? 589 HIS A CG 1 ATOM 4421 N ND1 . HIS A 1 569 ? -40.182 -20.838 24.884 1.00 16.94 ? 589 HIS A ND1 1 ATOM 4422 C CD2 . HIS A 1 569 ? -40.464 -19.111 23.575 1.00 16.55 ? 589 HIS A CD2 1 ATOM 4423 C CE1 . HIS A 1 569 ? -39.455 -21.041 23.800 1.00 18.48 ? 589 HIS A CE1 1 ATOM 4424 N NE2 . HIS A 1 569 ? -39.607 -20.007 22.992 1.00 17.19 ? 589 HIS A NE2 1 ATOM 4425 N N . LYS A 1 570 ? -43.954 -20.369 27.908 1.00 19.90 ? 590 LYS A N 1 ATOM 4426 C CA . LYS A 1 570 ? -44.732 -20.219 29.135 1.00 19.76 ? 590 LYS A CA 1 ATOM 4427 C C . LYS A 1 570 ? -44.184 -19.068 29.986 1.00 19.91 ? 590 LYS A C 1 ATOM 4428 O O . LYS A 1 570 ? -42.964 -18.838 30.080 1.00 19.36 ? 590 LYS A O 1 ATOM 4429 C CB . LYS A 1 570 ? -44.758 -21.526 29.943 1.00 19.90 ? 590 LYS A CB 1 ATOM 4430 C CG . LYS A 1 570 ? -45.612 -22.635 29.313 1.00 20.15 ? 590 LYS A CG 1 ATOM 4431 N N . ARG A 1 571 ? -45.107 -18.348 30.596 1.00 19.71 ? 591 ARG A N 1 ATOM 4432 C CA . ARG A 1 571 ? -44.774 -17.182 31.387 1.00 20.14 ? 591 ARG A CA 1 ATOM 4433 C C . ARG A 1 571 ? -44.261 -17.660 32.726 1.00 19.43 ? 591 ARG A C 1 ATOM 4434 O O . ARG A 1 571 ? -44.957 -18.374 33.438 1.00 19.55 ? 591 ARG A O 1 ATOM 4435 C CB . ARG A 1 571 ? -46.003 -16.304 31.555 1.00 20.34 ? 591 ARG A CB 1 ATOM 4436 C CG . ARG A 1 571 ? -46.598 -15.870 30.220 1.00 21.65 ? 591 ARG A CG 1 ATOM 4437 C CD . ARG A 1 571 ? -47.822 -15.020 30.446 1.00 22.57 ? 591 ARG A CD 1 ATOM 4438 N NE . ARG A 1 571 ? -47.433 -13.714 30.938 1.00 24.06 ? 591 ARG A NE 1 ATOM 4439 C CZ . ARG A 1 571 ? -48.246 -12.838 31.510 1.00 26.21 ? 591 ARG A CZ 1 ATOM 4440 N NH1 . ARG A 1 571 ? -49.536 -13.105 31.688 1.00 26.40 ? 591 ARG A NH1 1 ATOM 4441 N NH2 . ARG A 1 571 ? -47.750 -11.670 31.899 1.00 28.87 ? 591 ARG A NH2 1 ATOM 4442 N N . SER A 1 572 ? -43.026 -17.299 33.055 1.00 18.67 ? 592 SER A N 1 ATOM 4443 C CA A SER A 1 572 ? -42.376 -17.816 34.253 0.60 18.05 ? 592 SER A CA 1 ATOM 4444 C CA B SER A 1 572 ? -42.434 -17.788 34.289 0.40 18.41 ? 592 SER A CA 1 ATOM 4445 C C . SER A 1 572 ? -41.611 -16.736 35.010 1.00 18.15 ? 592 SER A C 1 ATOM 4446 O O . SER A 1 572 ? -41.293 -15.675 34.455 1.00 17.69 ? 592 SER A O 1 ATOM 4447 C CB A SER A 1 572 ? -41.410 -18.944 33.877 0.60 17.90 ? 592 SER A CB 1 ATOM 4448 C CB B SER A 1 572 ? -41.582 -19.027 34.011 0.40 18.37 ? 592 SER A CB 1 ATOM 4449 O OG A SER A 1 572 ? -42.024 -19.902 33.029 0.60 16.30 ? 592 SER A OG 1 ATOM 4450 O OG B SER A 1 572 ? -40.326 -18.678 33.473 0.40 18.62 ? 592 SER A OG 1 ATOM 4451 N N . TYR A 1 573 ? -41.329 -17.033 36.278 1.00 17.87 ? 593 TYR A N 1 ATOM 4452 C CA . TYR A 1 573 ? -40.381 -16.295 37.075 1.00 17.83 ? 593 TYR A CA 1 ATOM 4453 C C . TYR A 1 573 ? -39.331 -17.284 37.530 1.00 17.94 ? 593 TYR A C 1 ATOM 4454 O O . TYR A 1 573 ? -39.646 -18.413 37.870 1.00 18.39 ? 593 TYR A O 1 ATOM 4455 C CB . TYR A 1 573 ? -41.045 -15.597 38.265 1.00 17.49 ? 593 TYR A CB 1 ATOM 4456 C CG . TYR A 1 573 ? -41.154 -14.110 38.059 1.00 17.19 ? 593 TYR A CG 1 ATOM 4457 C CD1 . TYR A 1 573 ? -42.166 -13.574 37.274 1.00 16.01 ? 593 TYR A CD1 1 ATOM 4458 C CD2 . TYR A 1 573 ? -40.229 -13.239 38.626 1.00 16.97 ? 593 TYR A CD2 1 ATOM 4459 C CE1 . TYR A 1 573 ? -42.264 -12.209 37.064 1.00 16.86 ? 593 TYR A CE1 1 ATOM 4460 C CE2 . TYR A 1 573 ? -40.323 -11.864 38.434 1.00 16.85 ? 593 TYR A CE2 1 ATOM 4461 C CZ . TYR A 1 573 ? -41.354 -11.354 37.651 1.00 17.36 ? 593 TYR A CZ 1 ATOM 4462 O OH . TYR A 1 573 ? -41.464 -9.993 37.437 1.00 16.52 ? 593 TYR A OH 1 ATOM 4463 N N . ARG A 1 574 ? -38.079 -16.840 37.516 1.00 18.59 ? 594 ARG A N 1 ATOM 4464 C CA . ARG A 1 574 ? -36.928 -17.679 37.804 1.00 18.79 ? 594 ARG A CA 1 ATOM 4465 C C . ARG A 1 574 ? -36.396 -17.327 39.179 1.00 18.88 ? 594 ARG A C 1 ATOM 4466 O O . ARG A 1 574 ? -36.228 -16.141 39.484 1.00 18.70 ? 594 ARG A O 1 ATOM 4467 C CB . ARG A 1 574 ? -35.846 -17.403 36.758 1.00 19.04 ? 594 ARG A CB 1 ATOM 4468 C CG . ARG A 1 574 ? -34.526 -18.098 36.994 1.00 19.87 ? 594 ARG A CG 1 ATOM 4469 C CD . ARG A 1 574 ? -33.454 -17.561 36.055 1.00 20.34 ? 594 ARG A CD 1 ATOM 4470 N NE . ARG A 1 574 ? -32.168 -18.200 36.311 1.00 20.46 ? 594 ARG A NE 1 ATOM 4471 C CZ . ARG A 1 574 ? -31.007 -17.827 35.774 1.00 21.78 ? 594 ARG A CZ 1 ATOM 4472 N NH1 . ARG A 1 574 ? -30.928 -16.789 34.941 1.00 19.69 ? 594 ARG A NH1 1 ATOM 4473 N NH2 . ARG A 1 574 ? -29.903 -18.502 36.081 1.00 23.21 ? 594 ARG A NH2 1 ATOM 4474 N N . LEU A 1 575 ? -36.117 -18.347 39.996 1.00 18.78 ? 595 LEU A N 1 ATOM 4475 C CA . LEU A 1 575 ? -35.486 -18.143 41.296 1.00 19.33 ? 595 LEU A CA 1 ATOM 4476 C C . LEU A 1 575 ? -33.971 -18.361 41.172 1.00 19.95 ? 595 LEU A C 1 ATOM 4477 O O . LEU A 1 575 ? -33.519 -19.404 40.698 1.00 19.92 ? 595 LEU A O 1 ATOM 4478 C CB . LEU A 1 575 ? -36.067 -19.088 42.350 1.00 19.15 ? 595 LEU A CB 1 ATOM 4479 C CG . LEU A 1 575 ? -35.344 -19.116 43.710 1.00 20.16 ? 595 LEU A CG 1 ATOM 4480 C CD1 . LEU A 1 575 ? -35.659 -17.881 44.528 1.00 20.90 ? 595 LEU A CD1 1 ATOM 4481 C CD2 . LEU A 1 575 ? -35.714 -20.364 44.503 1.00 21.64 ? 595 LEU A CD2 1 ATOM 4482 N N . GLN A 1 576 ? -33.200 -17.376 41.615 1.00 20.63 ? 596 GLN A N 1 ATOM 4483 C CA . GLN A 1 576 ? -31.749 -17.426 41.541 1.00 21.83 ? 596 GLN A CA 1 ATOM 4484 C C . GLN A 1 576 ? -31.178 -17.202 42.939 1.00 21.96 ? 596 GLN A C 1 ATOM 4485 O O . GLN A 1 576 ? -31.368 -16.138 43.528 1.00 22.10 ? 596 GLN A O 1 ATOM 4486 C CB . GLN A 1 576 ? -31.273 -16.355 40.558 1.00 22.30 ? 596 GLN A CB 1 ATOM 4487 C CG . GLN A 1 576 ? -29.767 -16.259 40.373 1.00 24.67 ? 596 GLN A CG 1 ATOM 4488 C CD . GLN A 1 576 ? -29.389 -15.339 39.217 1.00 27.13 ? 596 GLN A CD 1 ATOM 4489 O OE1 . GLN A 1 576 ? -30.073 -15.298 38.183 1.00 28.34 ? 596 GLN A OE1 1 ATOM 4490 N NE2 . GLN A 1 576 ? -28.299 -14.585 39.391 1.00 28.30 ? 596 GLN A NE2 1 ATOM 4491 N N . ILE A 1 577 ? -30.488 -18.208 43.470 1.00 21.89 ? 597 ILE A N 1 ATOM 4492 C CA . ILE A 1 577 ? -30.056 -18.200 44.856 1.00 22.14 ? 597 ILE A CA 1 ATOM 4493 C C . ILE A 1 577 ? -28.596 -17.756 44.980 1.00 22.49 ? 597 ILE A C 1 ATOM 4494 O O . ILE A 1 577 ? -27.740 -18.252 44.252 1.00 22.30 ? 597 ILE A O 1 ATOM 4495 C CB . ILE A 1 577 ? -30.227 -19.595 45.487 1.00 22.10 ? 597 ILE A CB 1 ATOM 4496 C CG1 . ILE A 1 577 ? -31.724 -19.919 45.638 1.00 22.36 ? 597 ILE A CG1 1 ATOM 4497 C CG2 . ILE A 1 577 ? -29.500 -19.671 46.825 1.00 21.96 ? 597 ILE A CG2 1 ATOM 4498 C CD1 . ILE A 1 577 ? -32.043 -21.395 45.790 1.00 20.46 ? 597 ILE A CD1 1 ATOM 4499 N N A HIS A 1 578 ? -28.338 -16.836 45.912 0.50 22.60 ? 598 HIS A N 1 ATOM 4500 N N B HIS A 1 578 ? -28.338 -16.794 45.874 0.50 22.65 ? 598 HIS A N 1 ATOM 4501 C CA A HIS A 1 578 ? -26.995 -16.355 46.208 0.50 22.81 ? 598 HIS A CA 1 ATOM 4502 C CA B HIS A 1 578 ? -26.979 -16.361 46.205 0.50 22.90 ? 598 HIS A CA 1 ATOM 4503 C C A HIS A 1 578 ? -26.620 -16.779 47.622 0.50 22.88 ? 598 HIS A C 1 ATOM 4504 C C B HIS A 1 578 ? -26.642 -16.800 47.619 0.50 22.93 ? 598 HIS A C 1 ATOM 4505 O O A HIS A 1 578 ? -27.040 -16.152 48.602 0.50 22.58 ? 598 HIS A O 1 ATOM 4506 O O B HIS A 1 578 ? -27.104 -16.200 48.597 0.50 22.65 ? 598 HIS A O 1 ATOM 4507 C CB A HIS A 1 578 ? -26.936 -14.834 46.059 0.50 22.92 ? 598 HIS A CB 1 ATOM 4508 C CB B HIS A 1 578 ? -26.814 -14.843 46.091 0.50 23.05 ? 598 HIS A CB 1 ATOM 4509 C CG A HIS A 1 578 ? -27.136 -14.364 44.651 0.50 23.75 ? 598 HIS A CG 1 ATOM 4510 C CG B HIS A 1 578 ? -25.450 -14.361 46.482 0.50 23.98 ? 598 HIS A CG 1 ATOM 4511 N ND1 A HIS A 1 578 ? -26.252 -13.521 44.012 0.50 24.63 ? 598 HIS A ND1 1 ATOM 4512 N ND1 B HIS A 1 578 ? -25.230 -13.530 47.561 0.50 25.91 ? 598 HIS A ND1 1 ATOM 4513 C CD2 A HIS A 1 578 ? -28.112 -14.634 43.752 0.50 23.61 ? 598 HIS A CD2 1 ATOM 4514 C CD2 B HIS A 1 578 ? -24.230 -14.617 45.953 0.50 24.67 ? 598 HIS A CD2 1 ATOM 4515 C CE1 A HIS A 1 578 ? -26.678 -13.288 42.784 0.50 24.62 ? 598 HIS A CE1 1 ATOM 4516 C CE1 B HIS A 1 578 ? -23.936 -13.289 47.674 0.50 24.94 ? 598 HIS A CE1 1 ATOM 4517 N NE2 A HIS A 1 578 ? -27.803 -13.955 42.600 0.50 24.18 ? 598 HIS A NE2 1 ATOM 4518 N NE2 B HIS A 1 578 ? -23.307 -13.937 46.711 0.50 24.99 ? 598 HIS A NE2 1 ATOM 4519 N N . SER A 1 579 ? -25.830 -17.845 47.723 1.00 22.89 ? 599 SER A N 1 ATOM 4520 C CA . SER A 1 579 ? -25.566 -18.489 49.008 1.00 23.36 ? 599 SER A CA 1 ATOM 4521 C C . SER A 1 579 ? -24.264 -19.283 49.041 1.00 24.24 ? 599 SER A C 1 ATOM 4522 O O . SER A 1 579 ? -23.774 -19.736 48.009 1.00 23.31 ? 599 SER A O 1 ATOM 4523 C CB . SER A 1 579 ? -26.728 -19.439 49.333 1.00 23.06 ? 599 SER A CB 1 ATOM 4524 O OG . SER A 1 579 ? -26.569 -20.081 50.587 1.00 21.78 ? 599 SER A OG 1 ATOM 4525 N N . MET A 1 580 ? -23.735 -19.435 50.250 1.00 25.13 ? 600 MET A N 1 ATOM 4526 C CA A MET A 1 580 ? -22.585 -20.301 50.511 0.70 26.22 ? 600 MET A CA 1 ATOM 4527 C CA B MET A 1 580 ? -22.586 -20.291 50.508 0.30 25.68 ? 600 MET A CA 1 ATOM 4528 C C . MET A 1 580 ? -22.943 -21.366 51.539 1.00 26.01 ? 600 MET A C 1 ATOM 4529 O O . MET A 1 580 ? -22.063 -22.027 52.080 1.00 26.75 ? 600 MET A O 1 ATOM 4530 C CB A MET A 1 580 ? -21.390 -19.481 51.013 0.70 26.84 ? 600 MET A CB 1 ATOM 4531 C CB B MET A 1 580 ? -21.407 -19.444 50.994 0.30 25.82 ? 600 MET A CB 1 ATOM 4532 C CG A MET A 1 580 ? -20.653 -18.710 49.925 0.70 29.03 ? 600 MET A CG 1 ATOM 4533 C CG B MET A 1 580 ? -21.002 -18.337 50.018 0.30 26.11 ? 600 MET A CG 1 ATOM 4534 S SD A MET A 1 580 ? -19.108 -17.968 50.538 0.70 34.79 ? 600 MET A SD 1 ATOM 4535 S SD B MET A 1 580 ? -22.009 -16.838 50.118 0.30 27.08 ? 600 MET A SD 1 ATOM 4536 C CE A MET A 1 580 ? -18.136 -19.436 50.867 0.70 33.59 ? 600 MET A CE 1 ATOM 4537 C CE B MET A 1 580 ? -21.227 -15.962 51.473 0.30 26.95 ? 600 MET A CE 1 ATOM 4538 N N . ALA A 1 581 ? -24.241 -21.548 51.793 1.00 25.86 ? 601 ALA A N 1 ATOM 4539 C CA . ALA A 1 581 ? -24.725 -22.513 52.782 1.00 25.82 ? 601 ALA A CA 1 ATOM 4540 C C . ALA A 1 581 ? -24.511 -23.967 52.367 1.00 26.02 ? 601 ALA A C 1 ATOM 4541 O O . ALA A 1 581 ? -24.279 -24.277 51.206 1.00 26.16 ? 601 ALA A O 1 ATOM 4542 C CB . ALA A 1 581 ? -26.222 -22.270 53.089 1.00 25.43 ? 601 ALA A CB 1 ATOM 4543 N N . ASP A 1 582 ? -24.624 -24.855 53.343 1.00 26.66 ? 602 ASP A N 1 ATOM 4544 C CA . ASP A 1 582 ? -24.407 -26.279 53.152 1.00 27.21 ? 602 ASP A CA 1 ATOM 4545 C C . ASP A 1 582 ? -25.117 -26.975 54.304 1.00 26.78 ? 602 ASP A C 1 ATOM 4546 O O . ASP A 1 582 ? -25.695 -26.307 55.168 1.00 26.70 ? 602 ASP A O 1 ATOM 4547 C CB . ASP A 1 582 ? -22.903 -26.573 53.182 1.00 27.69 ? 602 ASP A CB 1 ATOM 4548 C CG . ASP A 1 582 ? -22.545 -27.903 52.541 1.00 30.39 ? 602 ASP A CG 1 ATOM 4549 O OD1 . ASP A 1 582 ? -23.456 -28.729 52.289 1.00 32.19 ? 602 ASP A OD1 1 ATOM 4550 O OD2 . ASP A 1 582 ? -21.334 -28.125 52.292 1.00 33.92 ? 602 ASP A OD2 1 ATOM 4551 N N . GLN A 1 583 ? -25.068 -28.302 54.328 1.00 26.40 ? 603 GLN A N 1 ATOM 4552 C CA . GLN A 1 583 ? -25.602 -29.065 55.443 1.00 26.35 ? 603 GLN A CA 1 ATOM 4553 C C . GLN A 1 583 ? -24.703 -28.855 56.670 1.00 26.43 ? 603 GLN A C 1 ATOM 4554 O O . GLN A 1 583 ? -23.491 -29.082 56.601 1.00 26.19 ? 603 GLN A O 1 ATOM 4555 C CB . GLN A 1 583 ? -25.683 -30.553 55.081 1.00 26.35 ? 603 GLN A CB 1 ATOM 4556 C CG . GLN A 1 583 ? -26.454 -31.388 56.081 1.00 26.32 ? 603 GLN A CG 1 ATOM 4557 C CD . GLN A 1 583 ? -27.879 -30.901 56.248 1.00 27.52 ? 603 GLN A CD 1 ATOM 4558 O OE1 . GLN A 1 583 ? -28.612 -30.774 55.271 1.00 28.24 ? 603 GLN A OE1 1 ATOM 4559 N NE2 . GLN A 1 583 ? -28.274 -30.609 57.484 1.00 25.99 ? 603 GLN A NE2 1 ATOM 4560 N N . VAL A 1 584 ? -25.288 -28.427 57.787 1.00 26.33 ? 604 VAL A N 1 ATOM 4561 C CA . VAL A 1 584 ? -24.500 -28.171 58.996 1.00 26.49 ? 604 VAL A CA 1 ATOM 4562 C C . VAL A 1 584 ? -24.660 -29.319 59.994 1.00 26.20 ? 604 VAL A C 1 ATOM 4563 O O . VAL A 1 584 ? -23.697 -30.036 60.291 1.00 26.31 ? 604 VAL A O 1 ATOM 4564 C CB . VAL A 1 584 ? -24.877 -26.822 59.638 1.00 26.60 ? 604 VAL A CB 1 ATOM 4565 C CG1 . VAL A 1 584 ? -24.031 -26.567 60.896 1.00 27.18 ? 604 VAL A CG1 1 ATOM 4566 C CG2 . VAL A 1 584 ? -24.697 -25.693 58.621 1.00 26.18 ? 604 VAL A CG2 1 ATOM 4567 N N . LEU A 1 585 ? -25.871 -29.512 60.498 1.00 25.57 ? 605 LEU A N 1 ATOM 4568 C CA . LEU A 1 585 ? -26.125 -30.596 61.443 1.00 25.31 ? 605 LEU A CA 1 ATOM 4569 C C . LEU A 1 585 ? -26.516 -31.854 60.664 1.00 25.25 ? 605 LEU A C 1 ATOM 4570 O O . LEU A 1 585 ? -27.029 -31.752 59.546 1.00 25.57 ? 605 LEU A O 1 ATOM 4571 C CB . LEU A 1 585 ? -27.236 -30.208 62.429 1.00 25.35 ? 605 LEU A CB 1 ATOM 4572 C CG . LEU A 1 585 ? -26.996 -28.970 63.296 1.00 24.92 ? 605 LEU A CG 1 ATOM 4573 C CD1 . LEU A 1 585 ? -28.199 -28.774 64.219 1.00 25.56 ? 605 LEU A CD1 1 ATOM 4574 C CD2 . LEU A 1 585 ? -25.688 -29.087 64.101 1.00 23.92 ? 605 LEU A CD2 1 ATOM 4575 N N . PRO A 1 586 ? -26.273 -33.047 61.241 1.00 25.12 ? 606 PRO A N 1 ATOM 4576 C CA . PRO A 1 586 ? -26.678 -34.273 60.551 1.00 25.00 ? 606 PRO A CA 1 ATOM 4577 C C . PRO A 1 586 ? -28.190 -34.450 60.590 1.00 25.06 ? 606 PRO A C 1 ATOM 4578 O O . PRO A 1 586 ? -28.795 -34.267 61.653 1.00 24.90 ? 606 PRO A O 1 ATOM 4579 C CB . PRO A 1 586 ? -25.977 -35.388 61.337 1.00 24.96 ? 606 PRO A CB 1 ATOM 4580 C CG . PRO A 1 586 ? -25.601 -34.795 62.643 1.00 25.27 ? 606 PRO A CG 1 ATOM 4581 C CD . PRO A 1 586 ? -25.655 -33.307 62.552 1.00 25.05 ? 606 PRO A CD 1 ATOM 4582 N N . PRO A 1 587 ? -28.805 -34.761 59.434 1.00 25.19 ? 607 PRO A N 1 ATOM 4583 C CA . PRO A 1 587 ? -30.249 -34.957 59.384 1.00 25.33 ? 607 PRO A CA 1 ATOM 4584 C C . PRO A 1 587 ? -30.731 -36.027 60.366 1.00 25.67 ? 607 PRO A C 1 ATOM 4585 O O . PRO A 1 587 ? -30.195 -37.133 60.391 1.00 25.97 ? 607 PRO A O 1 ATOM 4586 C CB . PRO A 1 587 ? -30.491 -35.393 57.938 1.00 25.64 ? 607 PRO A CB 1 ATOM 4587 C CG . PRO A 1 587 ? -29.375 -34.774 57.172 1.00 25.28 ? 607 PRO A CG 1 ATOM 4588 C CD . PRO A 1 587 ? -28.201 -34.786 58.089 1.00 24.97 ? 607 PRO A CD 1 ATOM 4589 N N . GLY A 1 588 ? -31.712 -35.676 61.186 1.00 25.74 ? 608 GLY A N 1 ATOM 4590 C CA . GLY A 1 588 ? -32.319 -36.616 62.112 1.00 26.04 ? 608 GLY A CA 1 ATOM 4591 C C . GLY A 1 588 ? -31.708 -36.608 63.504 1.00 26.01 ? 608 GLY A C 1 ATOM 4592 O O . GLY A 1 588 ? -32.212 -37.284 64.392 1.00 26.32 ? 608 GLY A O 1 ATOM 4593 N N . TRP A 1 589 ? -30.626 -35.860 63.711 1.00 25.69 ? 609 TRP A N 1 ATOM 4594 C CA . TRP A 1 589 ? -29.967 -35.863 65.010 1.00 25.25 ? 609 TRP A CA 1 ATOM 4595 C C . TRP A 1 589 ? -30.485 -34.757 65.944 1.00 25.08 ? 609 TRP A C 1 ATOM 4596 O O . TRP A 1 589 ? -30.209 -33.576 65.740 1.00 24.71 ? 609 TRP A O 1 ATOM 4597 C CB . TRP A 1 589 ? -28.452 -35.742 64.862 1.00 25.23 ? 609 TRP A CB 1 ATOM 4598 C CG . TRP A 1 589 ? -27.790 -35.660 66.220 1.00 25.69 ? 609 TRP A CG 1 ATOM 4599 C CD1 . TRP A 1 589 ? -27.281 -34.545 66.823 1.00 25.09 ? 609 TRP A CD1 1 ATOM 4600 C CD2 . TRP A 1 589 ? -27.634 -36.734 67.157 1.00 25.46 ? 609 TRP A CD2 1 ATOM 4601 N NE1 . TRP A 1 589 ? -26.791 -34.862 68.072 1.00 26.88 ? 609 TRP A NE1 1 ATOM 4602 C CE2 . TRP A 1 589 ? -26.996 -36.201 68.302 1.00 26.55 ? 609 TRP A CE2 1 ATOM 4603 C CE3 . TRP A 1 589 ? -27.953 -38.101 67.130 1.00 26.02 ? 609 TRP A CE3 1 ATOM 4604 C CZ2 . TRP A 1 589 ? -26.670 -36.984 69.416 1.00 26.91 ? 609 TRP A CZ2 1 ATOM 4605 C CZ3 . TRP A 1 589 ? -27.632 -38.890 68.248 1.00 27.44 ? 609 TRP A CZ3 1 ATOM 4606 C CH2 . TRP A 1 589 ? -27.000 -38.322 69.376 1.00 27.40 ? 609 TRP A CH2 1 ATOM 4607 N N . GLN A 1 590 ? -31.244 -35.158 66.958 1.00 25.06 ? 610 GLN A N 1 ATOM 4608 C CA . GLN A 1 590 ? -31.613 -34.299 68.076 1.00 25.32 ? 610 GLN A CA 1 ATOM 4609 C C . GLN A 1 590 ? -32.137 -32.910 67.666 1.00 25.16 ? 610 GLN A C 1 ATOM 4610 O O . GLN A 1 590 ? -33.223 -32.811 67.096 1.00 25.03 ? 610 GLN A O 1 ATOM 4611 C CB . GLN A 1 590 ? -30.425 -34.209 69.041 1.00 25.59 ? 610 GLN A CB 1 ATOM 4612 C CG . GLN A 1 590 ? -30.060 -35.543 69.691 1.00 27.35 ? 610 GLN A CG 1 ATOM 4613 C CD . GLN A 1 590 ? -31.160 -36.082 70.608 1.00 29.26 ? 610 GLN A CD 1 ATOM 4614 O OE1 . GLN A 1 590 ? -31.919 -35.319 71.204 1.00 32.90 ? 610 GLN A OE1 1 ATOM 4615 N NE2 . GLN A 1 590 ? -31.249 -37.397 70.715 1.00 30.47 ? 610 GLN A NE2 1 ATOM 4616 N N . GLU A 1 591 ? -31.362 -31.853 67.926 1.00 25.31 ? 611 GLU A N 1 ATOM 4617 C CA . GLU A 1 591 ? -31.822 -30.467 67.732 1.00 25.32 ? 611 GLU A CA 1 ATOM 4618 C C . GLU A 1 591 ? -32.042 -30.122 66.256 1.00 24.67 ? 611 GLU A C 1 ATOM 4619 O O . GLU A 1 591 ? -32.713 -29.140 65.941 1.00 24.67 ? 611 GLU A O 1 ATOM 4620 C CB . GLU A 1 591 ? -30.820 -29.460 68.314 1.00 25.77 ? 611 GLU A CB 1 ATOM 4621 C CG . GLU A 1 591 ? -30.501 -29.603 69.801 1.00 27.71 ? 611 GLU A CG 1 ATOM 4622 C CD . GLU A 1 591 ? -29.375 -30.587 70.101 1.00 30.02 ? 611 GLU A CD 1 ATOM 4623 O OE1 . GLU A 1 591 ? -28.715 -31.094 69.162 1.00 31.50 ? 611 GLU A OE1 1 ATOM 4624 O OE2 . GLU A 1 591 ? -29.151 -30.864 71.297 1.00 34.25 ? 611 GLU A OE2 1 ATOM 4625 N N . GLU A 1 592 ? -31.449 -30.910 65.360 1.00 23.73 ? 612 GLU A N 1 ATOM 4626 C CA . GLU A 1 592 ? -31.604 -30.710 63.924 1.00 23.16 ? 612 GLU A CA 1 ATOM 4627 C C . GLU A 1 592 ? -33.067 -30.798 63.510 1.00 22.54 ? 612 GLU A C 1 ATOM 4628 O O . GLU A 1 592 ? -33.445 -30.270 62.466 1.00 22.11 ? 612 GLU A O 1 ATOM 4629 C CB . GLU A 1 592 ? -30.767 -31.729 63.133 1.00 22.90 ? 612 GLU A CB 1 ATOM 4630 C CG . GLU A 1 592 ? -30.693 -31.447 61.620 1.00 22.91 ? 612 GLU A CG 1 ATOM 4631 C CD . GLU A 1 592 ? -31.880 -31.999 60.793 1.00 22.39 ? 612 GLU A CD 1 ATOM 4632 O OE1 . GLU A 1 592 ? -32.650 -32.871 61.274 1.00 20.07 ? 612 GLU A OE1 1 ATOM 4633 O OE2 . GLU A 1 592 ? -32.032 -31.557 59.630 1.00 21.79 ? 612 GLU A OE2 1 ATOM 4634 N N . GLN A 1 593 ? -33.889 -31.449 64.332 1.00 22.24 ? 613 GLN A N 1 ATOM 4635 C CA . GLN A 1 593 ? -35.342 -31.471 64.125 1.00 22.17 ? 613 GLN A CA 1 ATOM 4636 C C . GLN A 1 593 ? -35.968 -30.052 64.080 1.00 21.95 ? 613 GLN A C 1 ATOM 4637 O O . GLN A 1 593 ? -37.032 -29.848 63.477 1.00 21.38 ? 613 GLN A O 1 ATOM 4638 C CB . GLN A 1 593 ? -36.010 -32.312 65.223 1.00 22.34 ? 613 GLN A CB 1 ATOM 4639 C CG . GLN A 1 593 ? -37.496 -32.645 64.985 1.00 23.31 ? 613 GLN A CG 1 ATOM 4640 C CD . GLN A 1 593 ? -37.718 -33.719 63.915 1.00 24.61 ? 613 GLN A CD 1 ATOM 4641 O OE1 . GLN A 1 593 ? -36.811 -34.059 63.142 1.00 25.02 ? 613 GLN A OE1 1 ATOM 4642 N NE2 . GLN A 1 593 ? -38.933 -34.255 63.870 1.00 24.13 ? 613 GLN A NE2 1 ATOM 4643 N N . ALA A 1 594 ? -35.313 -29.084 64.727 1.00 21.37 ? 614 ALA A N 1 ATOM 4644 C CA . ALA A 1 594 ? -35.788 -27.700 64.745 1.00 21.13 ? 614 ALA A CA 1 ATOM 4645 C C . ALA A 1 594 ? -35.569 -27.006 63.403 1.00 20.96 ? 614 ALA A C 1 ATOM 4646 O O . ALA A 1 594 ? -36.304 -26.071 63.068 1.00 20.65 ? 614 ALA A O 1 ATOM 4647 C CB . ALA A 1 594 ? -35.080 -26.907 65.866 1.00 21.34 ? 614 ALA A CB 1 ATOM 4648 N N . ILE A 1 595 ? -34.565 -27.471 62.642 1.00 20.40 ? 615 ILE A N 1 ATOM 4649 C CA . ILE A 1 595 ? -34.126 -26.802 61.415 1.00 19.73 ? 615 ILE A CA 1 ATOM 4650 C C . ILE A 1 595 ? -34.018 -27.755 60.210 1.00 19.98 ? 615 ILE A C 1 ATOM 4651 O O . ILE A 1 595 ? -33.046 -27.720 59.441 1.00 20.31 ? 615 ILE A O 1 ATOM 4652 C CB . ILE A 1 595 ? -32.800 -26.026 61.662 1.00 19.95 ? 615 ILE A CB 1 ATOM 4653 C CG1 . ILE A 1 595 ? -31.647 -26.952 62.063 1.00 19.49 ? 615 ILE A CG1 1 ATOM 4654 C CG2 . ILE A 1 595 ? -33.007 -24.952 62.770 1.00 18.57 ? 615 ILE A CG2 1 ATOM 4655 C CD1 . ILE A 1 595 ? -30.259 -26.302 61.906 1.00 18.83 ? 615 ILE A CD1 1 ATOM 4656 N N . THR A 1 596 ? -35.041 -28.583 60.018 1.00 19.18 ? 616 THR A N 1 ATOM 4657 C CA . THR A 1 596 ? -35.047 -29.527 58.896 1.00 18.73 ? 616 THR A CA 1 ATOM 4658 C C . THR A 1 596 ? -35.147 -28.814 57.545 1.00 18.80 ? 616 THR A C 1 ATOM 4659 O O . THR A 1 596 ? -34.750 -29.364 56.521 1.00 18.94 ? 616 THR A O 1 ATOM 4660 C CB . THR A 1 596 ? -36.156 -30.596 59.036 1.00 18.37 ? 616 THR A CB 1 ATOM 4661 O OG1 . THR A 1 596 ? -37.441 -29.972 59.030 1.00 16.51 ? 616 THR A OG1 1 ATOM 4662 C CG2 . THR A 1 596 ? -35.978 -31.397 60.354 1.00 18.21 ? 616 THR A CG2 1 ATOM 4663 N N . TRP A 1 597 ? -35.648 -27.579 57.546 1.00 18.89 ? 617 TRP A N 1 ATOM 4664 C CA . TRP A 1 597 ? -35.638 -26.740 56.342 1.00 18.23 ? 617 TRP A CA 1 ATOM 4665 C C . TRP A 1 597 ? -34.227 -26.485 55.819 1.00 18.60 ? 617 TRP A C 1 ATOM 4666 O O . TRP A 1 597 ? -34.043 -26.316 54.619 1.00 18.82 ? 617 TRP A O 1 ATOM 4667 C CB . TRP A 1 597 ? -36.363 -25.410 56.565 1.00 18.10 ? 617 TRP A CB 1 ATOM 4668 C CG . TRP A 1 597 ? -35.957 -24.636 57.806 1.00 17.03 ? 617 TRP A CG 1 ATOM 4669 C CD1 . TRP A 1 597 ? -36.615 -24.615 59.004 1.00 16.82 ? 617 TRP A CD1 1 ATOM 4670 C CD2 . TRP A 1 597 ? -34.825 -23.767 57.959 1.00 16.40 ? 617 TRP A CD2 1 ATOM 4671 N NE1 . TRP A 1 597 ? -35.959 -23.798 59.891 1.00 16.88 ? 617 TRP A NE1 1 ATOM 4672 C CE2 . TRP A 1 597 ? -34.860 -23.262 59.273 1.00 15.66 ? 617 TRP A CE2 1 ATOM 4673 C CE3 . TRP A 1 597 ? -33.787 -23.358 57.107 1.00 17.94 ? 617 TRP A CE3 1 ATOM 4674 C CZ2 . TRP A 1 597 ? -33.897 -22.378 59.759 1.00 15.87 ? 617 TRP A CZ2 1 ATOM 4675 C CZ3 . TRP A 1 597 ? -32.825 -22.469 57.594 1.00 15.39 ? 617 TRP A CZ3 1 ATOM 4676 C CH2 . TRP A 1 597 ? -32.885 -22.002 58.910 1.00 16.02 ? 617 TRP A CH2 1 ATOM 4677 N N . ALA A 1 598 ? -33.242 -26.476 56.715 1.00 18.56 ? 618 ALA A N 1 ATOM 4678 C CA . ALA A 1 598 ? -31.860 -26.195 56.359 1.00 18.73 ? 618 ALA A CA 1 ATOM 4679 C C . ALA A 1 598 ? -31.199 -27.376 55.647 1.00 18.73 ? 618 ALA A C 1 ATOM 4680 O O . ALA A 1 598 ? -30.014 -27.331 55.335 1.00 18.77 ? 618 ALA A O 1 ATOM 4681 C CB . ALA A 1 598 ? -31.061 -25.797 57.601 1.00 18.62 ? 618 ALA A CB 1 ATOM 4682 N N . ARG A 1 599 ? -31.966 -28.439 55.409 1.00 18.72 ? 619 ARG A N 1 ATOM 4683 C CA . ARG A 1 599 ? -31.549 -29.507 54.504 1.00 18.38 ? 619 ARG A CA 1 ATOM 4684 C C . ARG A 1 599 ? -31.632 -29.089 53.042 1.00 18.30 ? 619 ARG A C 1 ATOM 4685 O O . ARG A 1 599 ? -30.996 -29.697 52.180 1.00 18.14 ? 619 ARG A O 1 ATOM 4686 C CB . ARG A 1 599 ? -32.437 -30.732 54.694 1.00 18.45 ? 619 ARG A CB 1 ATOM 4687 C CG . ARG A 1 599 ? -32.345 -31.346 56.067 1.00 18.67 ? 619 ARG A CG 1 ATOM 4688 C CD . ARG A 1 599 ? -33.304 -32.486 56.221 1.00 18.19 ? 619 ARG A CD 1 ATOM 4689 N NE . ARG A 1 599 ? -33.350 -32.982 57.593 1.00 19.06 ? 619 ARG A NE 1 ATOM 4690 C CZ . ARG A 1 599 ? -34.142 -33.975 57.997 1.00 19.94 ? 619 ARG A CZ 1 ATOM 4691 N NH1 . ARG A 1 599 ? -34.946 -34.587 57.136 1.00 20.23 ? 619 ARG A NH1 1 ATOM 4692 N NH2 . ARG A 1 599 ? -34.123 -34.365 59.259 1.00 19.90 ? 619 ARG A NH2 1 ATOM 4693 N N . TYR A 1 600 ? -32.435 -28.064 52.766 1.00 18.37 ? 620 TYR A N 1 ATOM 4694 C CA . TYR A 1 600 ? -32.849 -27.740 51.405 1.00 18.22 ? 620 TYR A CA 1 ATOM 4695 C C . TYR A 1 600 ? -32.531 -26.305 51.006 1.00 17.97 ? 620 TYR A C 1 ATOM 4696 O O . TYR A 1 600 ? -33.127 -25.373 51.550 1.00 18.27 ? 620 TYR A O 1 ATOM 4697 C CB . TYR A 1 600 ? -34.360 -27.969 51.278 1.00 18.54 ? 620 TYR A CB 1 ATOM 4698 C CG . TYR A 1 600 ? -34.789 -29.363 51.684 1.00 18.39 ? 620 TYR A CG 1 ATOM 4699 C CD1 . TYR A 1 600 ? -34.453 -30.469 50.902 1.00 19.55 ? 620 TYR A CD1 1 ATOM 4700 C CD2 . TYR A 1 600 ? -35.513 -29.580 52.846 1.00 18.60 ? 620 TYR A CD2 1 ATOM 4701 C CE1 . TYR A 1 600 ? -34.829 -31.761 51.272 1.00 20.23 ? 620 TYR A CE1 1 ATOM 4702 C CE2 . TYR A 1 600 ? -35.900 -30.868 53.228 1.00 18.85 ? 620 TYR A CE2 1 ATOM 4703 C CZ . TYR A 1 600 ? -35.565 -31.951 52.434 1.00 19.42 ? 620 TYR A CZ 1 ATOM 4704 O OH . TYR A 1 600 ? -35.942 -33.223 52.800 1.00 19.76 ? 620 TYR A OH 1 ATOM 4705 N N . PRO A 1 601 ? -31.600 -26.111 50.053 1.00 17.71 ? 621 PRO A N 1 ATOM 4706 C CA . PRO A 1 601 ? -31.505 -24.774 49.497 1.00 17.61 ? 621 PRO A CA 1 ATOM 4707 C C . PRO A 1 601 ? -32.818 -24.352 48.831 1.00 17.65 ? 621 PRO A C 1 ATOM 4708 O O . PRO A 1 601 ? -33.189 -23.185 48.900 1.00 17.78 ? 621 PRO A O 1 ATOM 4709 C CB . PRO A 1 601 ? -30.370 -24.884 48.472 1.00 17.32 ? 621 PRO A CB 1 ATOM 4710 C CG . PRO A 1 601 ? -30.141 -26.327 48.274 1.00 17.80 ? 621 PRO A CG 1 ATOM 4711 C CD . PRO A 1 601 ? -30.491 -26.959 49.587 1.00 18.03 ? 621 PRO A CD 1 ATOM 4712 N N . LEU A 1 602 ? -33.499 -25.300 48.195 1.00 17.47 ? 622 LEU A N 1 ATOM 4713 C CA . LEU A 1 602 ? -34.834 -25.061 47.647 1.00 17.42 ? 622 LEU A CA 1 ATOM 4714 C C . LEU A 1 602 ? -35.679 -26.288 47.872 1.00 17.03 ? 622 LEU A C 1 ATOM 4715 O O . LEU A 1 602 ? -35.236 -27.432 47.645 1.00 16.65 ? 622 LEU A O 1 ATOM 4716 C CB . LEU A 1 602 ? -34.801 -24.746 46.135 1.00 17.41 ? 622 LEU A CB 1 ATOM 4717 C CG . LEU A 1 602 ? -36.140 -24.728 45.377 1.00 18.17 ? 622 LEU A CG 1 ATOM 4718 C CD1 . LEU A 1 602 ? -37.013 -23.541 45.799 1.00 18.39 ? 622 LEU A CD1 1 ATOM 4719 C CD2 . LEU A 1 602 ? -35.931 -24.722 43.828 1.00 16.74 ? 622 LEU A CD2 1 ATOM 4720 N N . ALA A 1 603 ? -36.907 -26.033 48.301 1.00 16.66 ? 623 ALA A N 1 ATOM 4721 C CA . ALA A 1 603 ? -37.929 -27.043 48.364 1.00 16.63 ? 623 ALA A CA 1 ATOM 4722 C C . ALA A 1 603 ? -39.257 -26.382 47.988 1.00 16.71 ? 623 ALA A C 1 ATOM 4723 O O . ALA A 1 603 ? -39.491 -25.204 48.290 1.00 17.22 ? 623 ALA A O 1 ATOM 4724 C CB . ALA A 1 603 ? -37.973 -27.648 49.767 1.00 16.31 ? 623 ALA A CB 1 ATOM 4725 N N . VAL A 1 604 ? -40.115 -27.131 47.316 1.00 16.66 ? 624 VAL A N 1 ATOM 4726 C CA . VAL A 1 604 ? -41.398 -26.602 46.846 1.00 16.74 ? 624 VAL A CA 1 ATOM 4727 C C . VAL A 1 604 ? -42.526 -27.379 47.506 1.00 16.84 ? 624 VAL A C 1 ATOM 4728 O O . VAL A 1 604 ? -42.505 -28.609 47.504 1.00 17.83 ? 624 VAL A O 1 ATOM 4729 C CB . VAL A 1 604 ? -41.487 -26.714 45.302 1.00 16.70 ? 624 VAL A CB 1 ATOM 4730 C CG1 . VAL A 1 604 ? -42.786 -26.118 44.775 1.00 16.07 ? 624 VAL A CG1 1 ATOM 4731 C CG2 . VAL A 1 604 ? -40.280 -26.018 44.663 1.00 16.13 ? 624 VAL A CG2 1 ATOM 4732 N N . THR A 1 605 ? -43.489 -26.688 48.113 1.00 17.19 ? 625 THR A N 1 ATOM 4733 C CA . THR A 1 605 ? -44.646 -27.378 48.702 1.00 16.78 ? 625 THR A CA 1 ATOM 4734 C C . THR A 1 605 ? -45.971 -26.927 48.107 1.00 17.26 ? 625 THR A C 1 ATOM 4735 O O . THR A 1 605 ? -46.072 -25.867 47.504 1.00 17.63 ? 625 THR A O 1 ATOM 4736 C CB . THR A 1 605 ? -44.707 -27.248 50.247 1.00 17.11 ? 625 THR A CB 1 ATOM 4737 O OG1 . THR A 1 605 ? -44.818 -25.868 50.647 1.00 16.81 ? 625 THR A OG1 1 ATOM 4738 C CG2 . THR A 1 605 ? -43.476 -27.886 50.888 1.00 16.67 ? 625 THR A CG2 1 ATOM 4739 N N . LYS A 1 606 ? -46.988 -27.757 48.263 1.00 17.55 ? 626 LYS A N 1 ATOM 4740 C CA . LYS A 1 606 ? -48.353 -27.349 47.954 1.00 18.08 ? 626 LYS A CA 1 ATOM 4741 C C . LYS A 1 606 ? -48.870 -26.460 49.079 1.00 18.24 ? 626 LYS A C 1 ATOM 4742 O O . LYS A 1 606 ? -48.766 -26.823 50.253 1.00 18.67 ? 626 LYS A O 1 ATOM 4743 C CB . LYS A 1 606 ? -49.245 -28.571 47.803 1.00 18.13 ? 626 LYS A CB 1 ATOM 4744 C CG . LYS A 1 606 ? -50.732 -28.245 47.659 1.00 18.69 ? 626 LYS A CG 1 ATOM 4745 C CD . LYS A 1 606 ? -51.502 -29.468 47.227 1.00 19.49 ? 626 LYS A CD 1 ATOM 4746 C CE . LYS A 1 606 ? -53.006 -29.252 47.379 1.00 20.65 ? 626 LYS A CE 1 ATOM 4747 N NZ . LYS A 1 606 ? -53.695 -30.166 46.448 1.00 21.80 ? 626 LYS A NZ 1 ATOM 4748 N N . TYR A 1 607 ? -49.409 -25.295 48.718 1.00 19.07 ? 627 TYR A N 1 ATOM 4749 C CA . TYR A 1 607 ? -49.948 -24.335 49.690 1.00 19.28 ? 627 TYR A CA 1 ATOM 4750 C C . TYR A 1 607 ? -50.955 -24.977 50.660 1.00 19.88 ? 627 TYR A C 1 ATOM 4751 O O . TYR A 1 607 ? -51.756 -25.822 50.272 1.00 19.65 ? 627 TYR A O 1 ATOM 4752 C CB . TYR A 1 607 ? -50.624 -23.157 48.987 1.00 19.17 ? 627 TYR A CB 1 ATOM 4753 C CG . TYR A 1 607 ? -51.122 -22.106 49.956 1.00 19.84 ? 627 TYR A CG 1 ATOM 4754 C CD1 . TYR A 1 607 ? -52.392 -22.198 50.525 1.00 19.00 ? 627 TYR A CD1 1 ATOM 4755 C CD2 . TYR A 1 607 ? -50.314 -21.023 50.326 1.00 20.63 ? 627 TYR A CD2 1 ATOM 4756 C CE1 . TYR A 1 607 ? -52.843 -21.246 51.431 1.00 20.55 ? 627 TYR A CE1 1 ATOM 4757 C CE2 . TYR A 1 607 ? -50.770 -20.061 51.228 1.00 20.67 ? 627 TYR A CE2 1 ATOM 4758 C CZ . TYR A 1 607 ? -52.027 -20.184 51.778 1.00 20.65 ? 627 TYR A CZ 1 ATOM 4759 O OH . TYR A 1 607 ? -52.465 -19.245 52.667 1.00 21.66 ? 627 TYR A OH 1 ATOM 4760 N N . ARG A 1 608 ? -50.894 -24.549 51.912 1.00 20.34 ? 628 ARG A N 1 ATOM 4761 C CA . ARG A 1 608 ? -51.791 -25.033 52.944 1.00 21.60 ? 628 ARG A CA 1 ATOM 4762 C C . ARG A 1 608 ? -51.764 -24.056 54.120 1.00 21.36 ? 628 ARG A C 1 ATOM 4763 O O . ARG A 1 608 ? -50.683 -23.655 54.561 1.00 20.86 ? 628 ARG A O 1 ATOM 4764 C CB . ARG A 1 608 ? -51.325 -26.423 53.391 1.00 21.78 ? 628 ARG A CB 1 ATOM 4765 C CG . ARG A 1 608 ? -52.263 -27.127 54.287 1.00 22.87 ? 628 ARG A CG 1 ATOM 4766 C CD . ARG A 1 608 ? -51.943 -28.613 54.378 1.00 20.95 ? 628 ARG A CD 1 ATOM 4767 N NE . ARG A 1 608 ? -52.479 -29.277 53.199 1.00 19.68 ? 628 ARG A NE 1 ATOM 4768 C CZ . ARG A 1 608 ? -51.774 -29.883 52.254 1.00 18.09 ? 628 ARG A CZ 1 ATOM 4769 N NH1 . ARG A 1 608 ? -50.447 -29.971 52.313 1.00 19.61 ? 628 ARG A NH1 1 ATOM 4770 N NH2 . ARG A 1 608 ? -52.418 -30.423 51.237 1.00 18.09 ? 628 ARG A NH2 1 ATOM 4771 N N . GLU A 1 609 ? -52.947 -23.695 54.625 1.00 21.85 ? 629 GLU A N 1 ATOM 4772 C CA . GLU A 1 609 ? -53.084 -22.790 55.778 1.00 22.06 ? 629 GLU A CA 1 ATOM 4773 C C . GLU A 1 609 ? -52.458 -23.339 57.053 1.00 22.75 ? 629 GLU A C 1 ATOM 4774 O O . GLU A 1 609 ? -52.070 -22.580 57.945 1.00 23.27 ? 629 GLU A O 1 ATOM 4775 C CB . GLU A 1 609 ? -54.559 -22.474 56.045 1.00 22.20 ? 629 GLU A CB 1 ATOM 4776 C CG . GLU A 1 609 ? -55.239 -21.618 54.990 1.00 22.10 ? 629 GLU A CG 1 ATOM 4777 C CD . GLU A 1 609 ? -54.702 -20.189 54.940 1.00 23.45 ? 629 GLU A CD 1 ATOM 4778 O OE1 . GLU A 1 609 ? -54.268 -19.667 56.003 1.00 23.72 ? 629 GLU A OE1 1 ATOM 4779 O OE2 . GLU A 1 609 ? -54.724 -19.587 53.833 1.00 21.53 ? 629 GLU A OE2 1 ATOM 4780 N N . SER A 1 610 ? -52.382 -24.660 57.162 1.00 23.18 ? 630 SER A N 1 ATOM 4781 C CA . SER A 1 610 ? -51.686 -25.284 58.279 1.00 23.32 ? 630 SER A CA 1 ATOM 4782 C C . SER A 1 610 ? -50.166 -25.295 58.094 1.00 23.13 ? 630 SER A C 1 ATOM 4783 O O . SER A 1 610 ? -49.470 -25.788 58.971 1.00 24.19 ? 630 SER A O 1 ATOM 4784 C CB . SER A 1 610 ? -52.186 -26.720 58.493 1.00 23.22 ? 630 SER A CB 1 ATOM 4785 O OG . SER A 1 610 ? -52.155 -27.451 57.279 1.00 24.00 ? 630 SER A OG 1 ATOM 4786 N N . GLU A 1 611 ? -49.647 -24.740 56.997 1.00 22.50 ? 631 GLU A N 1 ATOM 4787 C CA . GLU A 1 611 ? -48.196 -24.763 56.722 1.00 22.26 ? 631 GLU A CA 1 ATOM 4788 C C . GLU A 1 611 ? -47.654 -23.392 56.302 1.00 22.17 ? 631 GLU A C 1 ATOM 4789 O O . GLU A 1 611 ? -46.801 -23.292 55.397 1.00 22.23 ? 631 GLU A O 1 ATOM 4790 C CB . GLU A 1 611 ? -47.866 -25.789 55.621 1.00 21.90 ? 631 GLU A CB 1 ATOM 4791 C CG . GLU A 1 611 ? -48.270 -27.214 55.940 1.00 22.22 ? 631 GLU A CG 1 ATOM 4792 C CD . GLU A 1 611 ? -48.033 -28.178 54.786 1.00 22.66 ? 631 GLU A CD 1 ATOM 4793 O OE1 . GLU A 1 611 ? -47.374 -27.796 53.787 1.00 22.16 ? 631 GLU A OE1 1 ATOM 4794 O OE2 . GLU A 1 611 ? -48.525 -29.324 54.877 1.00 22.37 ? 631 GLU A OE2 1 ATOM 4795 N N . LEU A 1 612 ? -48.136 -22.339 56.960 1.00 21.80 ? 632 LEU A N 1 ATOM 4796 C CA . LEU A 1 612 ? -47.739 -20.976 56.616 1.00 21.74 ? 632 LEU A CA 1 ATOM 4797 C C . LEU A 1 612 ? -46.319 -20.649 57.087 1.00 21.83 ? 632 LEU A C 1 ATOM 4798 O O . LEU A 1 612 ? -45.702 -19.726 56.562 1.00 21.39 ? 632 LEU A O 1 ATOM 4799 C CB . LEU A 1 612 ? -48.709 -19.953 57.221 1.00 21.56 ? 632 LEU A CB 1 ATOM 4800 C CG . LEU A 1 612 ? -50.179 -20.098 56.809 1.00 22.82 ? 632 LEU A CG 1 ATOM 4801 C CD1 . LEU A 1 612 ? -51.079 -19.175 57.629 1.00 23.11 ? 632 LEU A CD1 1 ATOM 4802 C CD2 . LEU A 1 612 ? -50.346 -19.848 55.324 1.00 23.26 ? 632 LEU A CD2 1 ATOM 4803 N N . CYS A 1 613 ? -45.826 -21.375 58.093 1.00 21.54 ? 633 CYS A N 1 ATOM 4804 C CA . CYS A 1 613 ? -44.539 -21.069 58.693 1.00 22.35 ? 633 CYS A CA 1 ATOM 4805 C C . CYS A 1 613 ? -43.673 -22.292 58.858 1.00 21.37 ? 633 CYS A C 1 ATOM 4806 O O . CYS A 1 613 ? -44.163 -23.383 59.150 1.00 21.10 ? 633 CYS A O 1 ATOM 4807 C CB . CYS A 1 613 ? -44.712 -20.420 60.067 1.00 22.44 ? 633 CYS A CB 1 ATOM 4808 S SG . CYS A 1 613 ? -45.604 -18.875 60.003 1.00 28.94 ? 633 CYS A SG 1 ATOM 4809 N N . SER A 1 614 ? -42.375 -22.089 58.676 1.00 20.87 ? 634 SER A N 1 ATOM 4810 C CA . SER A 1 614 ? -41.406 -23.162 58.819 1.00 20.42 ? 634 SER A CA 1 ATOM 4811 C C . SER A 1 614 ? -40.797 -23.137 60.205 1.00 19.99 ? 634 SER A C 1 ATOM 4812 O O . SER A 1 614 ? -40.138 -24.092 60.606 1.00 20.46 ? 634 SER A O 1 ATOM 4813 C CB . SER A 1 614 ? -40.319 -23.055 57.754 1.00 20.77 ? 634 SER A CB 1 ATOM 4814 O OG . SER A 1 614 ? -39.677 -21.785 57.771 1.00 20.06 ? 634 SER A OG 1 ATOM 4815 N N . SER A 1 615 ? -40.999 -22.053 60.948 1.00 19.30 ? 635 SER A N 1 ATOM 4816 C CA . SER A 1 615 ? -40.520 -22.011 62.329 1.00 18.95 ? 635 SER A CA 1 ATOM 4817 C C . SER A 1 615 ? -41.543 -21.394 63.260 1.00 18.37 ? 635 SER A C 1 ATOM 4818 O O . SER A 1 615 ? -42.711 -21.270 62.915 1.00 18.20 ? 635 SER A O 1 ATOM 4819 C CB . SER A 1 615 ? -39.190 -21.273 62.421 1.00 18.86 ? 635 SER A CB 1 ATOM 4820 O OG . SER A 1 615 ? -38.546 -21.597 63.639 1.00 19.54 ? 635 SER A OG 1 ATOM 4821 N N . SER A 1 616 ? -41.098 -21.029 64.452 1.00 18.03 ? 636 SER A N 1 ATOM 4822 C CA . SER A 1 616 ? -41.961 -20.428 65.440 1.00 18.09 ? 636 SER A CA 1 ATOM 4823 C C . SER A 1 616 ? -41.103 -19.886 66.560 1.00 18.58 ? 636 SER A C 1 ATOM 4824 O O . SER A 1 616 ? -39.905 -20.212 66.666 1.00 18.52 ? 636 SER A O 1 ATOM 4825 C CB . SER A 1 616 ? -42.945 -21.459 66.017 1.00 18.08 ? 636 SER A CB 1 ATOM 4826 O OG . SER A 1 616 ? -42.315 -22.220 67.037 1.00 17.53 ? 636 SER A OG 1 ATOM 4827 N N . ILE A 1 617 ? -41.729 -19.086 67.413 1.00 19.08 ? 637 ILE A N 1 ATOM 4828 C CA . ILE A 1 617 ? -41.066 -18.568 68.613 1.00 19.76 ? 637 ILE A CA 1 ATOM 4829 C C . ILE A 1 617 ? -40.701 -19.631 69.633 1.00 19.88 ? 637 ILE A C 1 ATOM 4830 O O . ILE A 1 617 ? -39.915 -19.351 70.522 1.00 20.93 ? 637 ILE A O 1 ATOM 4831 C CB . ILE A 1 617 ? -41.907 -17.450 69.330 1.00 19.74 ? 637 ILE A CB 1 ATOM 4832 C CG1 . ILE A 1 617 ? -43.247 -17.988 69.861 1.00 20.19 ? 637 ILE A CG1 1 ATOM 4833 C CG2 . ILE A 1 617 ? -42.104 -16.268 68.377 1.00 19.64 ? 637 ILE A CG2 1 ATOM 4834 C CD1 . ILE A 1 617 ? -44.004 -17.012 70.767 1.00 19.71 ? 637 ILE A CD1 1 ATOM 4835 N N . TYR A 1 618 ? -41.255 -20.840 69.510 1.00 20.32 ? 638 TYR A N 1 ATOM 4836 C CA . TYR A 1 618 ? -40.989 -21.923 70.473 1.00 20.29 ? 638 TYR A CA 1 ATOM 4837 C C . TYR A 1 618 ? -39.793 -22.817 70.104 1.00 20.46 ? 638 TYR A C 1 ATOM 4838 O O . TYR A 1 618 ? -39.302 -23.573 70.950 1.00 19.73 ? 638 TYR A O 1 ATOM 4839 C CB . TYR A 1 618 ? -42.236 -22.780 70.643 1.00 20.54 ? 638 TYR A CB 1 ATOM 4840 C CG . TYR A 1 618 ? -43.469 -21.946 70.933 1.00 21.04 ? 638 TYR A CG 1 ATOM 4841 C CD1 . TYR A 1 618 ? -44.429 -21.732 69.948 1.00 22.00 ? 638 TYR A CD1 1 ATOM 4842 C CD2 . TYR A 1 618 ? -43.651 -21.342 72.177 1.00 22.43 ? 638 TYR A CD2 1 ATOM 4843 C CE1 . TYR A 1 618 ? -45.555 -20.955 70.192 1.00 23.28 ? 638 TYR A CE1 1 ATOM 4844 C CE2 . TYR A 1 618 ? -44.780 -20.551 72.434 1.00 23.55 ? 638 TYR A CE2 1 ATOM 4845 C CZ . TYR A 1 618 ? -45.724 -20.363 71.437 1.00 23.50 ? 638 TYR A CZ 1 ATOM 4846 O OH . TYR A 1 618 ? -46.834 -19.588 71.662 1.00 24.69 ? 638 TYR A OH 1 ATOM 4847 N N . HIS A 1 619 ? -39.326 -22.717 68.861 1.00 19.95 ? 639 HIS A N 1 ATOM 4848 C CA . HIS A 1 619 ? -38.271 -23.609 68.362 1.00 20.40 ? 639 HIS A CA 1 ATOM 4849 C C . HIS A 1 619 ? -36.945 -23.476 69.109 1.00 20.64 ? 639 HIS A C 1 ATOM 4850 O O . HIS A 1 619 ? -36.254 -24.473 69.307 1.00 20.50 ? 639 HIS A O 1 ATOM 4851 C CB . HIS A 1 619 ? -38.026 -23.388 66.863 1.00 20.22 ? 639 HIS A CB 1 ATOM 4852 C CG . HIS A 1 619 ? -39.016 -24.085 65.981 1.00 19.92 ? 639 HIS A CG 1 ATOM 4853 N ND1 . HIS A 1 619 ? -40.371 -23.832 66.031 1.00 18.66 ? 639 HIS A ND1 1 ATOM 4854 C CD2 . HIS A 1 619 ? -38.840 -25.014 65.012 1.00 18.34 ? 639 HIS A CD2 1 ATOM 4855 C CE1 . HIS A 1 619 ? -40.986 -24.591 65.142 1.00 19.50 ? 639 HIS A CE1 1 ATOM 4856 N NE2 . HIS A 1 619 ? -40.079 -25.314 64.508 1.00 18.26 ? 639 HIS A NE2 1 ATOM 4857 N N . GLN A 1 620 ? -36.592 -22.254 69.509 1.00 20.89 ? 640 GLN A N 1 ATOM 4858 C CA . GLN A 1 620 ? -35.317 -22.008 70.188 1.00 21.01 ? 640 GLN A CA 1 ATOM 4859 C C . GLN A 1 620 ? -35.190 -22.839 71.465 1.00 21.32 ? 640 GLN A C 1 ATOM 4860 O O . GLN A 1 620 ? -34.158 -23.451 71.709 1.00 20.81 ? 640 GLN A O 1 ATOM 4861 C CB . GLN A 1 620 ? -35.177 -20.525 70.522 1.00 20.92 ? 640 GLN A CB 1 ATOM 4862 C CG . GLN A 1 620 ? -33.980 -20.156 71.397 1.00 20.56 ? 640 GLN A CG 1 ATOM 4863 C CD . GLN A 1 620 ? -32.632 -20.308 70.683 1.00 20.85 ? 640 GLN A CD 1 ATOM 4864 O OE1 . GLN A 1 620 ? -32.034 -19.318 70.268 1.00 20.44 ? 640 GLN A OE1 1 ATOM 4865 N NE2 . GLN A 1 620 ? -32.147 -21.544 70.563 1.00 20.02 ? 640 GLN A NE2 1 ATOM 4866 N N . ASN A 1 621 ? -36.244 -22.842 72.280 1.00 21.61 ? 641 ASN A N 1 ATOM 4867 C CA . ASN A 1 621 ? -36.192 -23.487 73.601 1.00 21.70 ? 641 ASN A CA 1 ATOM 4868 C C . ASN A 1 621 ? -36.763 -24.912 73.670 1.00 21.72 ? 641 ASN A C 1 ATOM 4869 O O . ASN A 1 621 ? -36.636 -25.566 74.703 1.00 22.26 ? 641 ASN A O 1 ATOM 4870 C CB . ASN A 1 621 ? -36.833 -22.583 74.661 1.00 21.24 ? 641 ASN A CB 1 ATOM 4871 C CG . ASN A 1 621 ? -35.997 -21.350 74.962 1.00 21.44 ? 641 ASN A CG 1 ATOM 4872 O OD1 . ASN A 1 621 ? -34.777 -21.319 74.712 1.00 20.67 ? 641 ASN A OD1 1 ATOM 4873 N ND2 . ASN A 1 621 ? -36.641 -20.333 75.528 1.00 18.74 ? 641 ASN A ND2 1 ATOM 4874 N N . ASP A 1 622 ? -37.375 -25.402 72.595 1.00 22.08 ? 642 ASP A N 1 ATOM 4875 C CA . ASP A 1 622 ? -37.560 -26.862 72.430 1.00 22.13 ? 642 ASP A CA 1 ATOM 4876 C C . ASP A 1 622 ? -37.272 -27.313 70.997 1.00 22.25 ? 642 ASP A C 1 ATOM 4877 O O . ASP A 1 622 ? -38.193 -27.683 70.250 1.00 21.25 ? 642 ASP A O 1 ATOM 4878 C CB . ASP A 1 622 ? -38.961 -27.319 72.848 1.00 22.36 ? 642 ASP A CB 1 ATOM 4879 C CG . ASP A 1 622 ? -39.088 -28.842 72.903 1.00 23.13 ? 642 ASP A CG 1 ATOM 4880 O OD1 . ASP A 1 622 ? -38.120 -29.552 72.514 1.00 23.30 ? 642 ASP A OD1 1 ATOM 4881 O OD2 . ASP A 1 622 ? -40.156 -29.329 73.340 1.00 24.27 ? 642 ASP A OD2 1 ATOM 4882 N N . PRO A 1 623 ? -35.986 -27.306 70.618 1.00 22.62 ? 643 PRO A N 1 ATOM 4883 C CA . PRO A 1 623 ? -35.581 -27.728 69.284 1.00 23.36 ? 643 PRO A CA 1 ATOM 4884 C C . PRO A 1 623 ? -35.728 -29.228 69.050 1.00 23.58 ? 643 PRO A C 1 ATOM 4885 O O . PRO A 1 623 ? -35.721 -29.673 67.900 1.00 23.92 ? 643 PRO A O 1 ATOM 4886 C CB . PRO A 1 623 ? -34.100 -27.315 69.220 1.00 23.42 ? 643 PRO A CB 1 ATOM 4887 C CG . PRO A 1 623 ? -33.662 -27.288 70.647 1.00 23.22 ? 643 PRO A CG 1 ATOM 4888 C CD . PRO A 1 623 ? -34.844 -26.806 71.405 1.00 22.79 ? 643 PRO A CD 1 ATOM 4889 N N . TRP A 1 624 ? -35.870 -29.989 70.133 1.00 23.75 ? 644 TRP A N 1 ATOM 4890 C CA . TRP A 1 624 ? -36.013 -31.436 70.067 1.00 23.62 ? 644 TRP A CA 1 ATOM 4891 C C . TRP A 1 624 ? -37.415 -31.840 69.617 1.00 23.93 ? 644 TRP A C 1 ATOM 4892 O O . TRP A 1 624 ? -37.569 -32.816 68.885 1.00 24.65 ? 644 TRP A O 1 ATOM 4893 C CB . TRP A 1 624 ? -35.670 -32.062 71.431 1.00 23.64 ? 644 TRP A CB 1 ATOM 4894 C CG . TRP A 1 624 ? -34.289 -31.687 71.909 1.00 23.15 ? 644 TRP A CG 1 ATOM 4895 C CD1 . TRP A 1 624 ? -33.121 -32.244 71.517 1.00 23.56 ? 644 TRP A CD1 1 ATOM 4896 C CD2 . TRP A 1 624 ? -33.945 -30.651 72.847 1.00 23.79 ? 644 TRP A CD2 1 ATOM 4897 N NE1 . TRP A 1 624 ? -32.059 -31.632 72.150 1.00 24.94 ? 644 TRP A NE1 1 ATOM 4898 C CE2 . TRP A 1 624 ? -32.540 -30.652 72.975 1.00 24.42 ? 644 TRP A CE2 1 ATOM 4899 C CE3 . TRP A 1 624 ? -34.689 -29.734 73.598 1.00 24.37 ? 644 TRP A CE3 1 ATOM 4900 C CZ2 . TRP A 1 624 ? -31.863 -29.771 73.816 1.00 24.76 ? 644 TRP A CZ2 1 ATOM 4901 C CZ3 . TRP A 1 624 ? -34.017 -28.861 74.432 1.00 24.13 ? 644 TRP A CZ3 1 ATOM 4902 C CH2 . TRP A 1 624 ? -32.615 -28.885 74.536 1.00 24.70 ? 644 TRP A CH2 1 ATOM 4903 N N . ASP A 1 625 ? -38.429 -31.081 70.014 1.00 23.71 ? 645 ASP A N 1 ATOM 4904 C CA . ASP A 1 625 ? -39.815 -31.458 69.730 1.00 23.71 ? 645 ASP A CA 1 ATOM 4905 C C . ASP A 1 625 ? -40.664 -30.216 69.445 1.00 23.45 ? 645 ASP A C 1 ATOM 4906 O O . ASP A 1 625 ? -41.633 -29.943 70.151 1.00 23.55 ? 645 ASP A O 1 ATOM 4907 C CB . ASP A 1 625 ? -40.362 -32.258 70.919 1.00 23.89 ? 645 ASP A CB 1 ATOM 4908 C CG . ASP A 1 625 ? -41.719 -32.899 70.650 1.00 25.15 ? 645 ASP A CG 1 ATOM 4909 O OD1 . ASP A 1 625 ? -42.216 -32.879 69.490 1.00 24.14 ? 645 ASP A OD1 1 ATOM 4910 O OD2 . ASP A 1 625 ? -42.285 -33.435 71.629 1.00 26.19 ? 645 ASP A OD2 1 ATOM 4911 N N . PRO A 1 626 ? -40.310 -29.465 68.384 1.00 23.34 ? 646 PRO A N 1 ATOM 4912 C CA . PRO A 1 626 ? -40.959 -28.182 68.088 1.00 23.28 ? 646 PRO A CA 1 ATOM 4913 C C . PRO A 1 626 ? -42.313 -28.358 67.398 1.00 23.17 ? 646 PRO A C 1 ATOM 4914 O O . PRO A 1 626 ? -42.593 -29.434 66.900 1.00 22.99 ? 646 PRO A O 1 ATOM 4915 C CB . PRO A 1 626 ? -39.966 -27.517 67.142 1.00 23.39 ? 646 PRO A CB 1 ATOM 4916 C CG . PRO A 1 626 ? -39.376 -28.669 66.374 1.00 23.56 ? 646 PRO A CG 1 ATOM 4917 C CD . PRO A 1 626 ? -39.311 -29.818 67.359 1.00 23.59 ? 646 PRO A CD 1 ATOM 4918 N N . PRO A 1 627 ? -43.142 -27.294 67.351 1.00 23.08 ? 647 PRO A N 1 ATOM 4919 C CA . PRO A 1 627 ? -44.506 -27.431 66.810 1.00 22.98 ? 647 PRO A CA 1 ATOM 4920 C C . PRO A 1 627 ? -44.598 -27.497 65.283 1.00 22.55 ? 647 PRO A C 1 ATOM 4921 O O . PRO A 1 627 ? -45.666 -27.789 64.750 1.00 22.39 ? 647 PRO A O 1 ATOM 4922 C CB . PRO A 1 627 ? -45.223 -26.178 67.330 1.00 22.74 ? 647 PRO A CB 1 ATOM 4923 C CG . PRO A 1 627 ? -44.130 -25.184 67.547 1.00 23.46 ? 647 PRO A CG 1 ATOM 4924 C CD . PRO A 1 627 ? -42.890 -25.946 67.895 1.00 23.03 ? 647 PRO A CD 1 ATOM 4925 N N . VAL A 1 628 ? -43.504 -27.207 64.590 1.00 22.30 ? 648 VAL A N 1 ATOM 4926 C CA . VAL A 1 628 ? -43.463 -27.298 63.135 1.00 22.06 ? 648 VAL A CA 1 ATOM 4927 C C . VAL A 1 628 ? -42.139 -27.936 62.733 1.00 21.48 ? 648 VAL A C 1 ATOM 4928 O O . VAL A 1 628 ? -41.081 -27.477 63.166 1.00 21.09 ? 648 VAL A O 1 ATOM 4929 C CB . VAL A 1 628 ? -43.600 -25.909 62.467 1.00 22.45 ? 648 VAL A CB 1 ATOM 4930 C CG1 . VAL A 1 628 ? -43.413 -26.010 60.954 1.00 22.46 ? 648 VAL A CG1 1 ATOM 4931 C CG2 . VAL A 1 628 ? -44.952 -25.290 62.785 1.00 23.31 ? 648 VAL A CG2 1 ATOM 4932 N N . VAL A 1 629 ? -42.215 -29.015 61.948 1.00 20.61 ? 649 VAL A N 1 ATOM 4933 C CA . VAL A 1 629 ? -41.035 -29.681 61.400 1.00 20.57 ? 649 VAL A CA 1 ATOM 4934 C C . VAL A 1 629 ? -41.162 -29.628 59.885 1.00 20.57 ? 649 VAL A C 1 ATOM 4935 O O . VAL A 1 629 ? -42.023 -30.294 59.293 1.00 20.83 ? 649 VAL A O 1 ATOM 4936 C CB . VAL A 1 629 ? -40.895 -31.145 61.902 1.00 21.14 ? 649 VAL A CB 1 ATOM 4937 C CG1 . VAL A 1 629 ? -39.644 -31.820 61.292 1.00 19.76 ? 649 VAL A CG1 1 ATOM 4938 C CG2 . VAL A 1 629 ? -40.820 -31.186 63.429 1.00 20.12 ? 649 VAL A CG2 1 ATOM 4939 N N . PHE A 1 630 ? -40.333 -28.805 59.250 1.00 20.28 ? 650 PHE A N 1 ATOM 4940 C CA . PHE A 1 630 ? -40.499 -28.526 57.823 1.00 19.99 ? 650 PHE A CA 1 ATOM 4941 C C . PHE A 1 630 ? -40.523 -29.814 56.987 1.00 20.18 ? 650 PHE A C 1 ATOM 4942 O O . PHE A 1 630 ? -41.297 -29.919 56.034 1.00 19.60 ? 650 PHE A O 1 ATOM 4943 C CB . PHE A 1 630 ? -39.421 -27.573 57.306 1.00 19.75 ? 650 PHE A CB 1 ATOM 4944 C CG . PHE A 1 630 ? -39.514 -27.323 55.830 1.00 19.78 ? 650 PHE A CG 1 ATOM 4945 C CD1 . PHE A 1 630 ? -40.400 -26.383 55.331 1.00 19.47 ? 650 PHE A CD1 1 ATOM 4946 C CD2 . PHE A 1 630 ? -38.751 -28.070 54.935 1.00 18.22 ? 650 PHE A CD2 1 ATOM 4947 C CE1 . PHE A 1 630 ? -40.504 -26.168 53.968 1.00 19.32 ? 650 PHE A CE1 1 ATOM 4948 C CE2 . PHE A 1 630 ? -38.850 -27.862 53.574 1.00 18.89 ? 650 PHE A CE2 1 ATOM 4949 C CZ . PHE A 1 630 ? -39.727 -26.911 53.084 1.00 19.19 ? 650 PHE A CZ 1 ATOM 4950 N N . GLU A 1 631 ? -39.682 -30.781 57.346 1.00 20.36 ? 651 GLU A N 1 ATOM 4951 C CA . GLU A 1 631 ? -39.626 -32.083 56.641 1.00 20.79 ? 651 GLU A CA 1 ATOM 4952 C C . GLU A 1 631 ? -41.005 -32.737 56.511 1.00 20.71 ? 651 GLU A C 1 ATOM 4953 O O . GLU A 1 631 ? -41.300 -33.394 55.506 1.00 21.34 ? 651 GLU A O 1 ATOM 4954 C CB . GLU A 1 631 ? -38.654 -33.036 57.354 1.00 20.90 ? 651 GLU A CB 1 ATOM 4955 C CG . GLU A 1 631 ? -38.473 -34.419 56.703 1.00 21.70 ? 651 GLU A CG 1 ATOM 4956 C CD . GLU A 1 631 ? -37.683 -34.389 55.396 1.00 22.22 ? 651 GLU A CD 1 ATOM 4957 O OE1 . GLU A 1 631 ? -37.031 -33.368 55.091 1.00 22.05 ? 651 GLU A OE1 1 ATOM 4958 O OE2 . GLU A 1 631 ? -37.706 -35.410 54.678 1.00 23.80 ? 651 GLU A OE2 1 ATOM 4959 N N . GLN A 1 632 ? -41.856 -32.534 57.509 1.00 20.77 ? 652 GLN A N 1 ATOM 4960 C CA . GLN A 1 632 ? -43.188 -33.112 57.504 1.00 20.94 ? 652 GLN A CA 1 ATOM 4961 C C . GLN A 1 632 ? -44.071 -32.579 56.377 1.00 20.57 ? 652 GLN A C 1 ATOM 4962 O O . GLN A 1 632 ? -44.980 -33.278 55.933 1.00 20.38 ? 652 GLN A O 1 ATOM 4963 C CB . GLN A 1 632 ? -43.864 -32.959 58.880 1.00 21.43 ? 652 GLN A CB 1 ATOM 4964 C CG . GLN A 1 632 ? -43.157 -33.750 59.988 1.00 23.46 ? 652 GLN A CG 1 ATOM 4965 C CD . GLN A 1 632 ? -43.792 -33.597 61.379 1.00 26.74 ? 652 GLN A CD 1 ATOM 4966 O OE1 . GLN A 1 632 ? -44.757 -32.849 61.571 1.00 28.82 ? 652 GLN A OE1 1 ATOM 4967 N NE2 . GLN A 1 632 ? -43.235 -34.308 62.356 1.00 27.00 ? 652 GLN A NE2 1 ATOM 4968 N N . PHE A 1 633 ? -43.792 -31.363 55.897 1.00 20.09 ? 653 PHE A N 1 ATOM 4969 C CA . PHE A 1 633 ? -44.516 -30.793 54.762 1.00 19.61 ? 653 PHE A CA 1 ATOM 4970 C C . PHE A 1 633 ? -44.259 -31.601 53.479 1.00 19.57 ? 653 PHE A C 1 ATOM 4971 O O . PHE A 1 633 ? -45.064 -31.558 52.533 1.00 18.84 ? 653 PHE A O 1 ATOM 4972 C CB . PHE A 1 633 ? -44.103 -29.334 54.486 1.00 19.48 ? 653 PHE A CB 1 ATOM 4973 C CG . PHE A 1 633 ? -44.325 -28.360 55.637 1.00 19.51 ? 653 PHE A CG 1 ATOM 4974 C CD1 . PHE A 1 633 ? -44.980 -28.720 56.813 1.00 20.30 ? 653 PHE A CD1 1 ATOM 4975 C CD2 . PHE A 1 633 ? -43.894 -27.048 55.501 1.00 19.67 ? 653 PHE A CD2 1 ATOM 4976 C CE1 . PHE A 1 633 ? -45.171 -27.796 57.829 1.00 20.92 ? 653 PHE A CE1 1 ATOM 4977 C CE2 . PHE A 1 633 ? -44.087 -26.124 56.507 1.00 20.52 ? 653 PHE A CE2 1 ATOM 4978 C CZ . PHE A 1 633 ? -44.728 -26.498 57.676 1.00 20.88 ? 653 PHE A CZ 1 ATOM 4979 N N . LEU A 1 634 ? -43.127 -32.307 53.442 1.00 19.55 ? 654 LEU A N 1 ATOM 4980 C CA . LEU A 1 634 ? -42.742 -33.126 52.285 1.00 19.75 ? 654 LEU A CA 1 ATOM 4981 C C . LEU A 1 634 ? -43.219 -34.584 52.387 1.00 19.63 ? 654 LEU A C 1 ATOM 4982 O O . LEU A 1 634 ? -43.227 -35.300 51.392 1.00 20.09 ? 654 LEU A O 1 ATOM 4983 C CB . LEU A 1 634 ? -41.214 -33.109 52.117 1.00 19.58 ? 654 LEU A CB 1 ATOM 4984 C CG . LEU A 1 634 ? -40.517 -31.743 52.081 1.00 19.90 ? 654 LEU A CG 1 ATOM 4985 C CD1 . LEU A 1 634 ? -38.998 -31.923 52.093 1.00 19.18 ? 654 LEU A CD1 1 ATOM 4986 C CD2 . LEU A 1 634 ? -40.953 -30.946 50.851 1.00 20.01 ? 654 LEU A CD2 1 ATOM 4987 N N . HIS A 1 635 ? -43.597 -35.022 53.581 1.00 19.38 ? 655 HIS A N 1 ATOM 4988 C CA . HIS A 1 635 ? -43.988 -36.412 53.804 1.00 19.66 ? 655 HIS A CA 1 ATOM 4989 C C . HIS A 1 635 ? -45.064 -36.943 52.858 1.00 19.37 ? 655 HIS A C 1 ATOM 4990 O O . HIS A 1 635 ? -44.939 -38.052 52.354 1.00 19.19 ? 655 HIS A O 1 ATOM 4991 C CB . HIS A 1 635 ? -44.443 -36.632 55.250 1.00 19.91 ? 655 HIS A CB 1 ATOM 4992 C CG . HIS A 1 635 ? -43.317 -36.690 56.229 1.00 20.46 ? 655 HIS A CG 1 ATOM 4993 N ND1 . HIS A 1 635 ? -43.518 -36.730 57.591 1.00 21.94 ? 655 HIS A ND1 1 ATOM 4994 C CD2 . HIS A 1 635 ? -41.975 -36.699 56.044 1.00 20.97 ? 655 HIS A CD2 1 ATOM 4995 C CE1 . HIS A 1 635 ? -42.345 -36.793 58.202 1.00 22.41 ? 655 HIS A CE1 1 ATOM 4996 N NE2 . HIS A 1 635 ? -41.394 -36.773 57.284 1.00 21.22 ? 655 HIS A NE2 1 ATOM 4997 N N . ASN A 1 636 ? -46.119 -36.170 52.638 1.00 19.12 ? 656 ASN A N 1 ATOM 4998 C CA . ASN A 1 636 ? -47.200 -36.624 51.780 1.00 18.63 ? 656 ASN A CA 1 ATOM 4999 C C . ASN A 1 636 ? -46.911 -36.498 50.274 1.00 18.66 ? 656 ASN A C 1 ATOM 5000 O O . ASN A 1 636 ? -47.722 -36.922 49.451 1.00 18.07 ? 656 ASN A O 1 ATOM 5001 C CB . ASN A 1 636 ? -48.534 -35.973 52.176 1.00 18.75 ? 656 ASN A CB 1 ATOM 5002 C CG . ASN A 1 636 ? -48.495 -34.447 52.157 1.00 18.60 ? 656 ASN A CG 1 ATOM 5003 O OD1 . ASN A 1 636 ? -47.533 -33.835 51.686 1.00 19.41 ? 656 ASN A OD1 1 ATOM 5004 N ND2 . ASN A 1 636 ? -49.548 -33.828 52.688 1.00 18.06 ? 656 ASN A ND2 1 ATOM 5005 N N . ASN A 1 637 ? -45.757 -35.931 49.922 1.00 18.70 ? 657 ASN A N 1 ATOM 5006 C CA . ASN A 1 637 ? -45.264 -35.935 48.541 1.00 19.07 ? 657 ASN A CA 1 ATOM 5007 C C . ASN A 1 637 ? -46.330 -35.617 47.500 1.00 19.27 ? 657 ASN A C 1 ATOM 5008 O O . ASN A 1 637 ? -46.559 -36.387 46.561 1.00 19.55 ? 657 ASN A O 1 ATOM 5009 C CB . ASN A 1 637 ? -44.607 -37.278 48.195 1.00 18.99 ? 657 ASN A CB 1 ATOM 5010 C CG . ASN A 1 637 ? -43.809 -37.211 46.911 1.00 19.25 ? 657 ASN A CG 1 ATOM 5011 O OD1 . ASN A 1 637 ? -43.422 -36.132 46.482 1.00 19.84 ? 657 ASN A OD1 1 ATOM 5012 N ND2 . ASN A 1 637 ? -43.576 -38.360 46.280 1.00 19.84 ? 657 ASN A ND2 1 ATOM 5013 N N . GLU A 1 638 ? -46.952 -34.462 47.658 1.00 19.21 ? 658 GLU A N 1 ATOM 5014 C CA . GLU A 1 638 ? -48.134 -34.127 46.885 1.00 19.57 ? 658 GLU A CA 1 ATOM 5015 C C . GLU A 1 638 ? -47.817 -33.744 45.461 1.00 19.61 ? 658 GLU A C 1 ATOM 5016 O O . GLU A 1 638 ? -46.699 -33.301 45.141 1.00 19.59 ? 658 GLU A O 1 ATOM 5017 C CB . GLU A 1 638 ? -48.905 -33.005 47.565 1.00 19.28 ? 658 GLU A CB 1 ATOM 5018 C CG . GLU A 1 638 ? -49.370 -33.382 48.940 1.00 19.02 ? 658 GLU A CG 1 ATOM 5019 C CD . GLU A 1 638 ? -50.007 -32.222 49.670 1.00 20.20 ? 658 GLU A CD 1 ATOM 5020 O OE1 . GLU A 1 638 ? -49.269 -31.451 50.322 1.00 16.48 ? 658 GLU A OE1 1 ATOM 5021 O OE2 . GLU A 1 638 ? -51.252 -32.096 49.603 1.00 19.80 ? 658 GLU A OE2 1 ATOM 5022 N N . ASN A 1 639 ? -48.814 -33.928 44.604 1.00 19.99 ? 659 ASN A N 1 ATOM 5023 C CA . ASN A 1 639 ? -48.694 -33.554 43.215 1.00 20.60 ? 659 ASN A CA 1 ATOM 5024 C C . ASN A 1 639 ? -48.567 -32.044 43.150 1.00 20.70 ? 659 ASN A C 1 ATOM 5025 O O . ASN A 1 639 ? -49.296 -31.338 43.841 1.00 20.45 ? 659 ASN A O 1 ATOM 5026 C CB . ASN A 1 639 ? -49.899 -34.032 42.405 1.00 20.80 ? 659 ASN A CB 1 ATOM 5027 C CG . ASN A 1 639 ? -49.690 -33.874 40.905 1.00 21.49 ? 659 ASN A CG 1 ATOM 5028 O OD1 . ASN A 1 639 ? -49.818 -32.774 40.374 1.00 22.02 ? 659 ASN A OD1 1 ATOM 5029 N ND2 . ASN A 1 639 ? -49.356 -34.972 40.221 1.00 20.73 ? 659 ASN A ND2 1 ATOM 5030 N N . ILE A 1 640 ? -47.629 -31.558 42.341 1.00 21.19 ? 660 ILE A N 1 ATOM 5031 C CA . ILE A 1 640 ? -47.403 -30.120 42.211 1.00 21.51 ? 660 ILE A CA 1 ATOM 5032 C C . ILE A 1 640 ? -47.516 -29.608 40.766 1.00 22.70 ? 660 ILE A C 1 ATOM 5033 O O . ILE A 1 640 ? -46.921 -28.587 40.412 1.00 22.40 ? 660 ILE A O 1 ATOM 5034 C CB . ILE A 1 640 ? -46.051 -29.714 42.833 1.00 21.24 ? 660 ILE A CB 1 ATOM 5035 C CG1 . ILE A 1 640 ? -44.900 -30.512 42.211 1.00 19.60 ? 660 ILE A CG1 1 ATOM 5036 C CG2 . ILE A 1 640 ? -46.123 -29.874 44.372 1.00 19.90 ? 660 ILE A CG2 1 ATOM 5037 C CD1 . ILE A 1 640 ? -43.515 -29.966 42.541 1.00 18.93 ? 660 ILE A CD1 1 ATOM 5038 N N . GLU A 1 641 ? -48.295 -30.310 39.948 1.00 23.68 ? 661 GLU A N 1 ATOM 5039 C CA . GLU A 1 641 ? -48.632 -29.842 38.608 1.00 24.67 ? 661 GLU A CA 1 ATOM 5040 C C . GLU A 1 641 ? -49.882 -28.973 38.745 1.00 25.04 ? 661 GLU A C 1 ATOM 5041 O O . GLU A 1 641 ? -50.874 -29.391 39.344 1.00 26.28 ? 661 GLU A O 1 ATOM 5042 C CB . GLU A 1 641 ? -48.943 -31.025 37.679 1.00 25.28 ? 661 GLU A CB 1 ATOM 5043 C CG . GLU A 1 641 ? -47.971 -32.216 37.730 1.00 27.89 ? 661 GLU A CG 1 ATOM 5044 C CD . GLU A 1 641 ? -48.525 -33.457 36.997 1.00 32.64 ? 661 GLU A CD 1 ATOM 5045 O OE1 . GLU A 1 641 ? -48.615 -34.545 37.611 1.00 36.29 ? 661 GLU A OE1 1 ATOM 5046 O OE2 . GLU A 1 641 ? -48.890 -33.348 35.805 1.00 36.32 ? 661 GLU A OE2 1 ATOM 5047 N N . ASN A 1 642 ? -49.851 -27.764 38.216 1.00 24.89 ? 662 ASN A N 1 ATOM 5048 C CA A ASN A 1 642 ? -51.019 -26.899 38.241 0.50 24.66 ? 662 ASN A CA 1 ATOM 5049 C CA B ASN A 1 642 ? -51.022 -26.895 38.248 0.50 24.81 ? 662 ASN A CA 1 ATOM 5050 C C . ASN A 1 642 ? -51.619 -26.819 39.651 1.00 24.33 ? 662 ASN A C 1 ATOM 5051 O O . ASN A 1 642 ? -52.773 -27.214 39.878 1.00 24.74 ? 662 ASN A O 1 ATOM 5052 C CB A ASN A 1 642 ? -52.055 -27.401 37.233 0.50 24.82 ? 662 ASN A CB 1 ATOM 5053 C CB B ASN A 1 642 ? -52.074 -27.384 37.250 0.50 25.07 ? 662 ASN A CB 1 ATOM 5054 C CG A ASN A 1 642 ? -53.030 -26.325 36.820 0.50 24.82 ? 662 ASN A CG 1 ATOM 5055 C CG B ASN A 1 642 ? -51.612 -27.262 35.821 0.50 25.69 ? 662 ASN A CG 1 ATOM 5056 O OD1 A ASN A 1 642 ? -52.633 -25.203 36.525 0.50 25.43 ? 662 ASN A OD1 1 ATOM 5057 O OD1 B ASN A 1 642 ? -51.484 -26.157 35.301 0.50 27.06 ? 662 ASN A OD1 1 ATOM 5058 N ND2 A ASN A 1 642 ? -54.313 -26.668 36.776 0.50 25.19 ? 662 ASN A ND2 1 ATOM 5059 N ND2 B ASN A 1 642 ? -51.366 -28.398 35.171 0.50 26.72 ? 662 ASN A ND2 1 ATOM 5060 N N . GLU A 1 643 ? -50.812 -26.319 40.584 1.00 23.16 ? 663 GLU A N 1 ATOM 5061 C CA A GLU A 1 643 ? -51.215 -26.154 41.983 0.50 22.68 ? 663 GLU A CA 1 ATOM 5062 C CA B GLU A 1 643 ? -51.208 -26.159 41.973 0.50 22.29 ? 663 GLU A CA 1 ATOM 5063 C C . GLU A 1 643 ? -50.672 -24.830 42.507 1.00 22.03 ? 663 GLU A C 1 ATOM 5064 O O . GLU A 1 643 ? -49.786 -24.225 41.901 1.00 21.76 ? 663 GLU A O 1 ATOM 5065 C CB A GLU A 1 643 ? -50.681 -27.299 42.862 0.50 22.70 ? 663 GLU A CB 1 ATOM 5066 C CB B GLU A 1 643 ? -50.660 -27.327 42.798 0.50 22.05 ? 663 GLU A CB 1 ATOM 5067 C CG A GLU A 1 643 ? -51.337 -28.663 42.640 0.50 23.29 ? 663 GLU A CG 1 ATOM 5068 C CG B GLU A 1 643 ? -51.203 -27.406 44.199 0.50 20.86 ? 663 GLU A CG 1 ATOM 5069 C CD A GLU A 1 643 ? -52.675 -28.809 43.341 0.50 23.44 ? 663 GLU A CD 1 ATOM 5070 C CD B GLU A 1 643 ? -52.683 -27.073 44.267 0.50 19.32 ? 663 GLU A CD 1 ATOM 5071 O OE1 A GLU A 1 643 ? -52.787 -28.444 44.526 0.50 23.58 ? 663 GLU A OE1 1 ATOM 5072 O OE1 B GLU A 1 643 ? -53.482 -27.691 43.520 0.50 18.91 ? 663 GLU A OE1 1 ATOM 5073 O OE2 A GLU A 1 643 ? -53.621 -29.306 42.709 0.50 25.75 ? 663 GLU A OE2 1 ATOM 5074 O OE2 B GLU A 1 643 ? -53.036 -26.181 45.066 0.50 15.48 ? 663 GLU A OE2 1 ATOM 5075 N N . ASP A 1 644 ? -51.219 -24.389 43.633 1.00 21.46 ? 664 ASP A N 1 ATOM 5076 C CA . ASP A 1 644 ? -50.697 -23.260 44.377 1.00 20.54 ? 664 ASP A CA 1 ATOM 5077 C C . ASP A 1 644 ? -49.423 -23.733 45.092 1.00 20.17 ? 664 ASP A C 1 ATOM 5078 O O . ASP A 1 644 ? -49.496 -24.486 46.067 1.00 20.09 ? 664 ASP A O 1 ATOM 5079 C CB . ASP A 1 644 ? -51.744 -22.768 45.380 1.00 20.15 ? 664 ASP A CB 1 ATOM 5080 C CG . ASP A 1 644 ? -51.328 -21.483 46.084 1.00 20.08 ? 664 ASP A CG 1 ATOM 5081 O OD1 . ASP A 1 644 ? -50.169 -21.049 45.924 1.00 17.60 ? 664 ASP A OD1 1 ATOM 5082 O OD2 . ASP A 1 644 ? -52.166 -20.907 46.805 1.00 18.17 ? 664 ASP A OD2 1 ATOM 5083 N N . LEU A 1 645 ? -48.268 -23.282 44.598 1.00 19.30 ? 665 LEU A N 1 ATOM 5084 C CA . LEU A 1 645 ? -46.961 -23.721 45.098 1.00 18.97 ? 665 LEU A CA 1 ATOM 5085 C C . LEU A 1 645 ? -46.333 -22.671 46.010 1.00 18.45 ? 665 LEU A C 1 ATOM 5086 O O . LEU A 1 645 ? -46.549 -21.472 45.841 1.00 18.51 ? 665 LEU A O 1 ATOM 5087 C CB . LEU A 1 645 ? -45.993 -23.995 43.926 1.00 18.80 ? 665 LEU A CB 1 ATOM 5088 C CG . LEU A 1 645 ? -46.476 -24.925 42.797 1.00 19.23 ? 665 LEU A CG 1 ATOM 5089 C CD1 . LEU A 1 645 ? -45.401 -25.084 41.695 1.00 18.93 ? 665 LEU A CD1 1 ATOM 5090 C CD2 . LEU A 1 645 ? -46.883 -26.287 43.358 1.00 18.18 ? 665 LEU A CD2 1 ATOM 5091 N N . VAL A 1 646 ? -45.542 -23.136 46.966 1.00 18.03 ? 666 VAL A N 1 ATOM 5092 C CA . VAL A 1 646 ? -44.692 -22.279 47.768 1.00 17.29 ? 666 VAL A CA 1 ATOM 5093 C C . VAL A 1 646 ? -43.249 -22.758 47.615 1.00 17.40 ? 666 VAL A C 1 ATOM 5094 O O . VAL A 1 646 ? -42.968 -23.925 47.844 1.00 18.05 ? 666 VAL A O 1 ATOM 5095 C CB . VAL A 1 646 ? -45.109 -22.346 49.249 1.00 17.37 ? 666 VAL A CB 1 ATOM 5096 C CG1 . VAL A 1 646 ? -44.225 -21.455 50.095 1.00 15.77 ? 666 VAL A CG1 1 ATOM 5097 C CG2 . VAL A 1 646 ? -46.607 -21.980 49.390 1.00 17.00 ? 666 VAL A CG2 1 ATOM 5098 N N . ALA A 1 647 ? -42.350 -21.869 47.201 1.00 17.18 ? 667 ALA A N 1 ATOM 5099 C CA . ALA A 1 647 ? -40.919 -22.147 47.212 1.00 17.19 ? 667 ALA A CA 1 ATOM 5100 C C . ALA A 1 647 ? -40.378 -21.758 48.581 1.00 17.16 ? 667 ALA A C 1 ATOM 5101 O O . ALA A 1 647 ? -40.791 -20.760 49.156 1.00 17.51 ? 667 ALA A O 1 ATOM 5102 C CB . ALA A 1 647 ? -40.194 -21.360 46.110 1.00 16.69 ? 667 ALA A CB 1 ATOM 5103 N N . TRP A 1 648 ? -39.494 -22.576 49.126 1.00 17.01 ? 668 TRP A N 1 ATOM 5104 C CA . TRP A 1 648 ? -38.855 -22.267 50.394 1.00 16.89 ? 668 TRP A CA 1 ATOM 5105 C C . TRP A 1 648 ? -37.364 -22.286 50.138 1.00 16.68 ? 668 TRP A C 1 ATOM 5106 O O . TRP A 1 648 ? -36.853 -23.246 49.545 1.00 17.03 ? 668 TRP A O 1 ATOM 5107 C CB . TRP A 1 648 ? -39.202 -23.295 51.465 1.00 16.60 ? 668 TRP A CB 1 ATOM 5108 C CG . TRP A 1 648 ? -40.664 -23.512 51.750 1.00 17.04 ? 668 TRP A CG 1 ATOM 5109 C CD1 . TRP A 1 648 ? -41.525 -24.296 51.044 1.00 17.11 ? 668 TRP A CD1 1 ATOM 5110 C CD2 . TRP A 1 648 ? -41.410 -22.996 52.860 1.00 16.67 ? 668 TRP A CD2 1 ATOM 5111 N NE1 . TRP A 1 648 ? -42.758 -24.297 51.637 1.00 17.10 ? 668 TRP A NE1 1 ATOM 5112 C CE2 . TRP A 1 648 ? -42.716 -23.506 52.755 1.00 17.55 ? 668 TRP A CE2 1 ATOM 5113 C CE3 . TRP A 1 648 ? -41.098 -22.150 53.933 1.00 16.67 ? 668 TRP A CE3 1 ATOM 5114 C CZ2 . TRP A 1 648 ? -43.721 -23.197 53.685 1.00 17.63 ? 668 TRP A CZ2 1 ATOM 5115 C CZ3 . TRP A 1 648 ? -42.097 -21.836 54.855 1.00 16.57 ? 668 TRP A CZ3 1 ATOM 5116 C CH2 . TRP A 1 648 ? -43.387 -22.368 54.733 1.00 15.63 ? 668 TRP A CH2 1 ATOM 5117 N N . VAL A 1 649 ? -36.672 -21.240 50.584 1.00 16.15 ? 669 VAL A N 1 ATOM 5118 C CA . VAL A 1 649 ? -35.269 -21.041 50.243 1.00 15.93 ? 669 VAL A CA 1 ATOM 5119 C C . VAL A 1 649 ? -34.409 -20.890 51.481 1.00 15.96 ? 669 VAL A C 1 ATOM 5120 O O . VAL A 1 649 ? -34.710 -20.089 52.361 1.00 15.72 ? 669 VAL A O 1 ATOM 5121 C CB . VAL A 1 649 ? -35.088 -19.791 49.369 1.00 16.19 ? 669 VAL A CB 1 ATOM 5122 C CG1 . VAL A 1 649 ? -33.624 -19.615 48.969 1.00 15.82 ? 669 VAL A CG1 1 ATOM 5123 C CG2 . VAL A 1 649 ? -35.986 -19.861 48.143 1.00 14.93 ? 669 VAL A CG2 1 ATOM 5124 N N . THR A 1 650 ? -33.348 -21.688 51.548 1.00 15.72 ? 670 THR A N 1 ATOM 5125 C CA . THR A 1 650 ? -32.325 -21.542 52.566 1.00 15.78 ? 670 THR A CA 1 ATOM 5126 C C . THR A 1 650 ? -31.112 -20.836 51.962 1.00 16.15 ? 670 THR A C 1 ATOM 5127 O O . THR A 1 650 ? -30.613 -21.220 50.897 1.00 15.85 ? 670 THR A O 1 ATOM 5128 C CB . THR A 1 650 ? -31.868 -22.917 53.095 1.00 15.86 ? 670 THR A CB 1 ATOM 5129 O OG1 . THR A 1 650 ? -32.943 -23.538 53.800 1.00 17.00 ? 670 THR A OG1 1 ATOM 5130 C CG2 . THR A 1 650 ? -30.643 -22.805 54.022 1.00 14.68 ? 670 THR A CG2 1 ATOM 5131 N N . VAL A 1 651 ? -30.639 -19.807 52.643 1.00 16.58 ? 671 VAL A N 1 ATOM 5132 C CA . VAL A 1 651 ? -29.377 -19.169 52.282 1.00 16.85 ? 671 VAL A CA 1 ATOM 5133 C C . VAL A 1 651 ? -28.550 -19.027 53.540 1.00 17.32 ? 671 VAL A C 1 ATOM 5134 O O . VAL A 1 651 ? -29.086 -19.104 54.652 1.00 17.49 ? 671 VAL A O 1 ATOM 5135 C CB . VAL A 1 651 ? -29.606 -17.787 51.607 1.00 16.76 ? 671 VAL A CB 1 ATOM 5136 C CG1 . VAL A 1 651 ? -30.390 -17.951 50.305 1.00 16.92 ? 671 VAL A CG1 1 ATOM 5137 C CG2 . VAL A 1 651 ? -30.339 -16.837 52.534 1.00 16.29 ? 671 VAL A CG2 1 ATOM 5138 N N . GLY A 1 652 ? -27.242 -18.847 53.369 1.00 17.74 ? 672 GLY A N 1 ATOM 5139 C CA . GLY A 1 652 ? -26.359 -18.581 54.489 1.00 17.84 ? 672 GLY A CA 1 ATOM 5140 C C . GLY A 1 652 ? -24.889 -18.735 54.148 1.00 18.36 ? 672 GLY A C 1 ATOM 5141 O O . GLY A 1 652 ? -24.515 -18.813 52.974 1.00 17.05 ? 672 GLY A O 1 ATOM 5142 N N . PHE A 1 653 ? -24.066 -18.797 55.192 1.00 18.73 ? 673 PHE A N 1 ATOM 5143 C CA . PHE A 1 653 ? -22.621 -18.909 55.038 1.00 19.18 ? 673 PHE A CA 1 ATOM 5144 C C . PHE A 1 653 ? -21.947 -19.329 56.332 1.00 19.52 ? 673 PHE A C 1 ATOM 5145 O O . PHE A 1 653 ? -22.399 -18.978 57.434 1.00 19.88 ? 673 PHE A O 1 ATOM 5146 C CB . PHE A 1 653 ? -22.015 -17.583 54.527 1.00 19.28 ? 673 PHE A CB 1 ATOM 5147 C CG . PHE A 1 653 ? -22.286 -16.377 55.421 1.00 20.07 ? 673 PHE A CG 1 ATOM 5148 C CD1 . PHE A 1 653 ? -21.330 -15.947 56.345 1.00 19.91 ? 673 PHE A CD1 1 ATOM 5149 C CD2 . PHE A 1 653 ? -23.470 -15.652 55.302 1.00 21.31 ? 673 PHE A CD2 1 ATOM 5150 C CE1 . PHE A 1 653 ? -21.560 -14.834 57.153 1.00 20.39 ? 673 PHE A CE1 1 ATOM 5151 C CE2 . PHE A 1 653 ? -23.722 -14.533 56.115 1.00 21.35 ? 673 PHE A CE2 1 ATOM 5152 C CZ . PHE A 1 653 ? -22.760 -14.124 57.047 1.00 20.60 ? 673 PHE A CZ 1 ATOM 5153 N N . LEU A 1 654 ? -20.879 -20.107 56.184 1.00 19.71 ? 674 LEU A N 1 ATOM 5154 C CA . LEU A 1 654 ? -19.957 -20.381 57.266 1.00 20.07 ? 674 LEU A CA 1 ATOM 5155 C C . LEU A 1 654 ? -19.221 -19.085 57.592 1.00 19.84 ? 674 LEU A C 1 ATOM 5156 O O . LEU A 1 654 ? -18.701 -18.409 56.700 1.00 19.79 ? 674 LEU A O 1 ATOM 5157 C CB . LEU A 1 654 ? -18.932 -21.460 56.859 1.00 20.31 ? 674 LEU A CB 1 ATOM 5158 C CG . LEU A 1 654 ? -17.876 -21.870 57.906 1.00 20.43 ? 674 LEU A CG 1 ATOM 5159 C CD1 . LEU A 1 654 ? -18.488 -22.643 59.084 1.00 19.19 ? 674 LEU A CD1 1 ATOM 5160 C CD2 . LEU A 1 654 ? -16.755 -22.676 57.267 1.00 19.06 ? 674 LEU A CD2 1 ATOM 5161 N N . HIS A 1 655 ? -19.191 -18.744 58.874 1.00 19.70 ? 675 HIS A N 1 ATOM 5162 C CA . HIS A 1 655 ? -18.396 -17.636 59.358 1.00 19.65 ? 675 HIS A CA 1 ATOM 5163 C C . HIS A 1 655 ? -17.316 -18.189 60.313 1.00 19.92 ? 675 HIS A C 1 ATOM 5164 O O . HIS A 1 655 ? -17.612 -18.651 61.427 1.00 19.65 ? 675 HIS A O 1 ATOM 5165 C CB . HIS A 1 655 ? -19.316 -16.602 60.026 1.00 19.86 ? 675 HIS A CB 1 ATOM 5166 C CG . HIS A 1 655 ? -18.607 -15.387 60.545 1.00 19.37 ? 675 HIS A CG 1 ATOM 5167 N ND1 . HIS A 1 655 ? -19.250 -14.417 61.281 1.00 18.92 ? 675 HIS A ND1 1 ATOM 5168 C CD2 . HIS A 1 655 ? -17.317 -14.988 60.441 1.00 19.10 ? 675 HIS A CD2 1 ATOM 5169 C CE1 . HIS A 1 655 ? -18.386 -13.474 61.608 1.00 20.86 ? 675 HIS A CE1 1 ATOM 5170 N NE2 . HIS A 1 655 ? -17.204 -13.797 61.111 1.00 20.25 ? 675 HIS A NE2 1 ATOM 5171 N N . ILE A 1 656 ? -16.069 -18.176 59.844 1.00 20.17 ? 676 ILE A N 1 ATOM 5172 C CA . ILE A 1 656 ? -14.902 -18.441 60.696 1.00 20.45 ? 676 ILE A CA 1 ATOM 5173 C C . ILE A 1 656 ? -14.390 -17.056 61.071 1.00 20.66 ? 676 ILE A C 1 ATOM 5174 O O . ILE A 1 656 ? -13.841 -16.353 60.213 1.00 21.15 ? 676 ILE A O 1 ATOM 5175 C CB . ILE A 1 656 ? -13.792 -19.227 59.954 1.00 20.63 ? 676 ILE A CB 1 ATOM 5176 C CG1 . ILE A 1 656 ? -14.275 -20.634 59.588 1.00 20.92 ? 676 ILE A CG1 1 ATOM 5177 C CG2 . ILE A 1 656 ? -12.507 -19.308 60.800 1.00 20.48 ? 676 ILE A CG2 1 ATOM 5178 C CD1 . ILE A 1 656 ? -13.362 -21.364 58.591 1.00 20.47 ? 676 ILE A CD1 1 ATOM 5179 N N . PRO A 1 657 ? -14.595 -16.629 62.331 1.00 20.77 ? 677 PRO A N 1 ATOM 5180 C CA . PRO A 1 657 ? -14.172 -15.261 62.627 1.00 20.56 ? 677 PRO A CA 1 ATOM 5181 C C . PRO A 1 657 ? -12.672 -15.005 62.414 1.00 20.92 ? 677 PRO A C 1 ATOM 5182 O O . PRO A 1 657 ? -11.845 -15.924 62.457 1.00 20.78 ? 677 PRO A O 1 ATOM 5183 C CB . PRO A 1 657 ? -14.564 -15.085 64.086 1.00 21.06 ? 677 PRO A CB 1 ATOM 5184 C CG . PRO A 1 657 ? -15.747 -16.023 64.258 1.00 20.91 ? 677 PRO A CG 1 ATOM 5185 C CD . PRO A 1 657 ? -15.367 -17.219 63.444 1.00 20.87 ? 677 PRO A CD 1 ATOM 5186 N N . HIS A 1 658 ? -12.355 -13.750 62.146 1.00 21.15 ? 678 HIS A N 1 ATOM 5187 C CA . HIS A 1 658 ? -10.993 -13.306 61.933 1.00 20.90 ? 678 HIS A CA 1 ATOM 5188 C C . HIS A 1 658 ? -10.858 -11.948 62.610 1.00 21.03 ? 678 HIS A C 1 ATOM 5189 O O . HIS A 1 658 ? -11.869 -11.322 62.961 1.00 21.14 ? 678 HIS A O 1 ATOM 5190 C CB . HIS A 1 658 ? -10.667 -13.240 60.425 1.00 20.97 ? 678 HIS A CB 1 ATOM 5191 C CG . HIS A 1 658 ? -11.791 -12.733 59.567 1.00 20.41 ? 678 HIS A CG 1 ATOM 5192 N ND1 . HIS A 1 658 ? -11.748 -11.510 58.929 1.00 20.96 ? 678 HIS A ND1 1 ATOM 5193 C CD2 . HIS A 1 658 ? -12.980 -13.292 59.224 1.00 20.39 ? 678 HIS A CD2 1 ATOM 5194 C CE1 . HIS A 1 658 ? -12.869 -11.332 58.245 1.00 21.96 ? 678 HIS A CE1 1 ATOM 5195 N NE2 . HIS A 1 658 ? -13.629 -12.403 58.398 1.00 19.60 ? 678 HIS A NE2 1 ATOM 5196 N N . SER A 1 659 ? -9.618 -11.501 62.793 1.00 21.15 ? 679 SER A N 1 ATOM 5197 C CA . SER A 1 659 ? -9.313 -10.294 63.565 1.00 21.18 ? 679 SER A CA 1 ATOM 5198 C C . SER A 1 659 ? -9.981 -9.030 63.034 1.00 21.36 ? 679 SER A C 1 ATOM 5199 O O . SER A 1 659 ? -10.304 -8.124 63.815 1.00 20.99 ? 679 SER A O 1 ATOM 5200 C CB . SER A 1 659 ? -7.797 -10.086 63.650 1.00 21.30 ? 679 SER A CB 1 ATOM 5201 O OG . SER A 1 659 ? -7.217 -10.030 62.367 1.00 21.53 ? 679 SER A OG 1 ATOM 5202 N N . GLU A 1 660 ? -10.210 -8.974 61.722 1.00 21.31 ? 680 GLU A N 1 ATOM 5203 C CA . GLU A 1 660 ? -10.965 -7.868 61.119 1.00 21.14 ? 680 GLU A CA 1 ATOM 5204 C C . GLU A 1 660 ? -12.425 -7.782 61.598 1.00 21.33 ? 680 GLU A C 1 ATOM 5205 O O . GLU A 1 660 ? -13.061 -6.741 61.436 1.00 21.46 ? 680 GLU A O 1 ATOM 5206 C CB . GLU A 1 660 ? -10.931 -7.950 59.584 1.00 21.07 ? 680 GLU A CB 1 ATOM 5207 C CG . GLU A 1 660 ? -9.541 -7.726 58.973 1.00 21.18 ? 680 GLU A CG 1 ATOM 5208 C CD . GLU A 1 660 ? -8.699 -8.982 58.868 1.00 20.93 ? 680 GLU A CD 1 ATOM 5209 O OE1 . GLU A 1 660 ? -9.187 -10.079 59.215 1.00 22.04 ? 680 GLU A OE1 1 ATOM 5210 O OE2 . GLU A 1 660 ? -7.535 -8.878 58.421 1.00 21.56 ? 680 GLU A OE2 1 ATOM 5211 N N . ASP A 1 661 ? -12.958 -8.848 62.196 1.00 21.24 ? 681 ASP A N 1 ATOM 5212 C CA . ASP A 1 661 ? -14.285 -8.765 62.844 1.00 21.58 ? 681 ASP A CA 1 ATOM 5213 C C . ASP A 1 661 ? -14.308 -7.931 64.140 1.00 21.64 ? 681 ASP A C 1 ATOM 5214 O O . ASP A 1 661 ? -15.360 -7.785 64.750 1.00 21.36 ? 681 ASP A O 1 ATOM 5215 C CB . ASP A 1 661 ? -14.837 -10.166 63.157 1.00 21.54 ? 681 ASP A CB 1 ATOM 5216 C CG . ASP A 1 661 ? -15.288 -10.917 61.926 1.00 21.13 ? 681 ASP A CG 1 ATOM 5217 O OD1 . ASP A 1 661 ? -15.901 -10.297 61.044 1.00 23.23 ? 681 ASP A OD1 1 ATOM 5218 O OD2 . ASP A 1 661 ? -15.063 -12.146 61.853 1.00 21.18 ? 681 ASP A OD2 1 ATOM 5219 N N . ILE A 1 662 ? -13.162 -7.408 64.576 1.00 21.88 ? 682 ILE A N 1 ATOM 5220 C CA . ILE A 1 662 ? -13.107 -6.587 65.786 1.00 22.02 ? 682 ILE A CA 1 ATOM 5221 C C . ILE A 1 662 ? -13.057 -5.099 65.451 1.00 21.87 ? 682 ILE A C 1 ATOM 5222 O O . ILE A 1 662 ? -12.175 -4.654 64.716 1.00 22.22 ? 682 ILE A O 1 ATOM 5223 C CB . ILE A 1 662 ? -11.869 -6.921 66.643 1.00 22.35 ? 682 ILE A CB 1 ATOM 5224 C CG1 . ILE A 1 662 ? -11.906 -8.381 67.107 1.00 22.66 ? 682 ILE A CG1 1 ATOM 5225 C CG2 . ILE A 1 662 ? -11.795 -5.979 67.848 1.00 22.85 ? 682 ILE A CG2 1 ATOM 5226 C CD1 . ILE A 1 662 ? -13.090 -8.740 67.999 1.00 21.55 ? 682 ILE A CD1 1 ATOM 5227 N N . PRO A 1 663 ? -13.975 -4.305 66.019 1.00 21.59 ? 683 PRO A N 1 ATOM 5228 C CA . PRO A 1 663 ? -15.006 -4.643 66.989 1.00 21.40 ? 683 PRO A CA 1 ATOM 5229 C C . PRO A 1 663 ? -16.246 -5.315 66.400 1.00 21.25 ? 683 PRO A C 1 ATOM 5230 O O . PRO A 1 663 ? -16.945 -6.032 67.113 1.00 21.41 ? 683 PRO A O 1 ATOM 5231 C CB . PRO A 1 663 ? -15.385 -3.278 67.556 1.00 21.58 ? 683 PRO A CB 1 ATOM 5232 C CG . PRO A 1 663 ? -15.172 -2.352 66.415 1.00 21.55 ? 683 PRO A CG 1 ATOM 5233 C CD . PRO A 1 663 ? -13.963 -2.864 65.721 1.00 21.47 ? 683 PRO A CD 1 ATOM 5234 N N . ASN A 1 664 ? -16.529 -5.074 65.128 1.00 21.19 ? 684 ASN A N 1 ATOM 5235 C CA . ASN A 1 664 ? -17.752 -5.589 64.502 1.00 21.72 ? 684 ASN A CA 1 ATOM 5236 C C . ASN A 1 664 ? -17.484 -6.306 63.187 1.00 21.73 ? 684 ASN A C 1 ATOM 5237 O O . ASN A 1 664 ? -16.554 -5.960 62.455 1.00 21.41 ? 684 ASN A O 1 ATOM 5238 C CB . ASN A 1 664 ? -18.693 -4.429 64.178 1.00 21.66 ? 684 ASN A CB 1 ATOM 5239 C CG . ASN A 1 664 ? -19.647 -4.075 65.305 1.00 21.94 ? 684 ASN A CG 1 ATOM 5240 O OD1 . ASN A 1 664 ? -20.654 -3.413 65.053 1.00 22.83 ? 684 ASN A OD1 1 ATOM 5241 N ND2 . ASN A 1 664 ? -19.357 -4.502 66.529 1.00 21.40 ? 684 ASN A ND2 1 ATOM 5242 N N A THR A 1 665 ? -18.320 -7.297 62.883 0.50 21.81 ? 685 THR A N 1 ATOM 5243 N N B THR A 1 665 ? -18.311 -7.299 62.875 0.50 22.02 ? 685 THR A N 1 ATOM 5244 C CA A THR A 1 665 ? -18.369 -7.874 61.548 0.50 21.67 ? 685 THR A CA 1 ATOM 5245 C CA B THR A 1 665 ? -18.309 -7.866 61.539 0.50 22.10 ? 685 THR A CA 1 ATOM 5246 C C A THR A 1 665 ? -18.833 -6.777 60.588 0.50 21.64 ? 685 THR A C 1 ATOM 5247 C C B THR A 1 665 ? -18.825 -6.789 60.588 0.50 21.86 ? 685 THR A C 1 ATOM 5248 O O A THR A 1 665 ? -19.693 -5.962 60.945 0.50 21.67 ? 685 THR A O 1 ATOM 5249 O O B THR A 1 665 ? -19.710 -6.004 60.949 0.50 21.90 ? 685 THR A O 1 ATOM 5250 C CB A THR A 1 665 ? -19.335 -9.073 61.501 0.50 21.88 ? 685 THR A CB 1 ATOM 5251 C CB B THR A 1 665 ? -19.174 -9.125 61.452 0.50 22.34 ? 685 THR A CB 1 ATOM 5252 O OG1 A THR A 1 665 ? -18.853 -10.110 62.365 0.50 21.99 ? 685 THR A OG1 1 ATOM 5253 O OG1 B THR A 1 665 ? -20.531 -8.803 61.778 0.50 23.34 ? 685 THR A OG1 1 ATOM 5254 C CG2 A THR A 1 665 ? -19.478 -9.618 60.081 0.50 21.08 ? 685 THR A CG2 1 ATOM 5255 C CG2 B THR A 1 665 ? -18.668 -10.172 62.417 0.50 22.55 ? 685 THR A CG2 1 ATOM 5256 N N . ALA A 1 666 ? -18.241 -6.729 59.395 1.00 21.33 ? 686 ALA A N 1 ATOM 5257 C CA . ALA A 1 666 ? -18.592 -5.715 58.399 1.00 21.23 ? 686 ALA A CA 1 ATOM 5258 C C . ALA A 1 666 ? -19.464 -6.341 57.299 1.00 21.06 ? 686 ALA A C 1 ATOM 5259 O O . ALA A 1 666 ? -19.431 -7.550 57.096 1.00 20.75 ? 686 ALA A O 1 ATOM 5260 C CB . ALA A 1 666 ? -17.317 -5.097 57.816 1.00 20.98 ? 686 ALA A CB 1 ATOM 5261 N N . THR A 1 667 ? -20.248 -5.519 56.601 1.00 21.51 ? 687 THR A N 1 ATOM 5262 C CA . THR A 1 667 ? -21.201 -6.016 55.589 1.00 21.61 ? 687 THR A CA 1 ATOM 5263 C C . THR A 1 667 ? -20.606 -6.443 54.232 1.00 22.06 ? 687 THR A C 1 ATOM 5264 O O . THR A 1 667 ? -21.206 -7.276 53.549 1.00 21.99 ? 687 THR A O 1 ATOM 5265 C CB . THR A 1 667 ? -22.340 -5.009 55.326 1.00 21.67 ? 687 THR A CB 1 ATOM 5266 O OG1 . THR A 1 667 ? -21.806 -3.803 54.762 1.00 20.34 ? 687 THR A OG1 1 ATOM 5267 C CG2 . THR A 1 667 ? -23.093 -4.700 56.628 1.00 21.55 ? 687 THR A CG2 1 ATOM 5268 N N . PRO A 1 668 ? -19.455 -5.865 53.819 1.00 22.82 ? 688 PRO A N 1 ATOM 5269 C CA . PRO A 1 668 ? -18.912 -6.272 52.508 1.00 23.13 ? 688 PRO A CA 1 ATOM 5270 C C . PRO A 1 668 ? -18.608 -7.769 52.440 1.00 23.41 ? 688 PRO A C 1 ATOM 5271 O O . PRO A 1 668 ? -17.899 -8.301 53.285 1.00 22.97 ? 688 PRO A O 1 ATOM 5272 C CB . PRO A 1 668 ? -17.638 -5.436 52.381 1.00 23.25 ? 688 PRO A CB 1 ATOM 5273 C CG . PRO A 1 668 ? -17.942 -4.207 53.185 1.00 23.39 ? 688 PRO A CG 1 ATOM 5274 C CD . PRO A 1 668 ? -18.741 -4.687 54.355 1.00 22.55 ? 688 PRO A CD 1 ATOM 5275 N N . GLY A 1 669 ? -19.208 -8.445 51.466 1.00 23.91 ? 689 GLY A N 1 ATOM 5276 C CA . GLY A 1 669 ? -19.061 -9.886 51.307 1.00 23.89 ? 689 GLY A CA 1 ATOM 5277 C C . GLY A 1 669 ? -19.814 -10.716 52.327 1.00 24.39 ? 689 GLY A C 1 ATOM 5278 O O . GLY A 1 669 ? -19.717 -11.943 52.305 1.00 24.06 ? 689 GLY A O 1 ATOM 5279 N N . ASN A 1 670 ? -20.540 -10.064 53.241 1.00 24.62 ? 690 ASN A N 1 ATOM 5280 C CA . ASN A 1 670 ? -21.289 -10.782 54.274 1.00 25.16 ? 690 ASN A CA 1 ATOM 5281 C C . ASN A 1 670 ? -22.799 -10.617 54.058 1.00 24.89 ? 690 ASN A C 1 ATOM 5282 O O . ASN A 1 670 ? -23.543 -10.260 54.983 1.00 24.65 ? 690 ASN A O 1 ATOM 5283 C CB . ASN A 1 670 ? -20.877 -10.335 55.684 1.00 25.15 ? 690 ASN A CB 1 ATOM 5284 C CG . ASN A 1 670 ? -19.548 -10.938 56.134 1.00 27.50 ? 690 ASN A CG 1 ATOM 5285 O OD1 . ASN A 1 670 ? -19.186 -12.038 55.723 1.00 28.43 ? 690 ASN A OD1 1 ATOM 5286 N ND2 . ASN A 1 670 ? -18.814 -10.213 56.998 1.00 27.04 ? 690 ASN A ND2 1 ATOM 5287 N N . SER A 1 671 ? -23.241 -10.873 52.830 1.00 24.32 ? 691 SER A N 1 ATOM 5288 C CA . SER A 1 671 ? -24.673 -10.915 52.543 1.00 24.42 ? 691 SER A CA 1 ATOM 5289 C C . SER A 1 671 ? -25.043 -12.096 51.664 1.00 23.67 ? 691 SER A C 1 ATOM 5290 O O . SER A 1 671 ? -24.217 -12.606 50.903 1.00 23.94 ? 691 SER A O 1 ATOM 5291 C CB . SER A 1 671 ? -25.164 -9.621 51.893 1.00 24.53 ? 691 SER A CB 1 ATOM 5292 O OG . SER A 1 671 ? -24.535 -9.387 50.654 1.00 26.83 ? 691 SER A OG 1 ATOM 5293 N N . VAL A 1 672 ? -26.298 -12.517 51.798 1.00 22.58 ? 692 VAL A N 1 ATOM 5294 C CA . VAL A 1 672 ? -26.850 -13.619 51.046 1.00 21.82 ? 692 VAL A CA 1 ATOM 5295 C C . VAL A 1 672 ? -28.312 -13.333 50.753 1.00 21.69 ? 692 VAL A C 1 ATOM 5296 O O . VAL A 1 672 ? -28.908 -12.417 51.313 1.00 21.50 ? 692 VAL A O 1 ATOM 5297 C CB . VAL A 1 672 ? -26.738 -14.957 51.816 1.00 22.10 ? 692 VAL A CB 1 ATOM 5298 C CG1 . VAL A 1 672 ? -25.324 -15.540 51.677 1.00 21.20 ? 692 VAL A CG1 1 ATOM 5299 C CG2 . VAL A 1 672 ? -27.132 -14.783 53.273 1.00 21.48 ? 692 VAL A CG2 1 ATOM 5300 N N . GLY A 1 673 ? -28.883 -14.118 49.861 1.00 21.18 ? 693 GLY A N 1 ATOM 5301 C CA . GLY A 1 673 ? -30.276 -13.960 49.504 1.00 20.92 ? 693 GLY A CA 1 ATOM 5302 C C . GLY A 1 673 ? -30.541 -14.579 48.154 1.00 20.26 ? 693 GLY A C 1 ATOM 5303 O O . GLY A 1 673 ? -29.875 -15.549 47.771 1.00 20.33 ? 693 GLY A O 1 ATOM 5304 N N . PHE A 1 674 ? -31.497 -13.999 47.432 1.00 19.65 ? 694 PHE A N 1 ATOM 5305 C CA . PHE A 1 674 ? -31.931 -14.527 46.144 1.00 19.29 ? 694 PHE A CA 1 ATOM 5306 C C . PHE A 1 674 ? -32.635 -13.478 45.291 1.00 19.64 ? 694 PHE A C 1 ATOM 5307 O O . PHE A 1 674 ? -33.060 -12.431 45.799 1.00 19.10 ? 694 PHE A O 1 ATOM 5308 C CB . PHE A 1 674 ? -32.868 -15.722 46.358 1.00 19.06 ? 694 PHE A CB 1 ATOM 5309 C CG . PHE A 1 674 ? -34.152 -15.380 47.077 1.00 18.21 ? 694 PHE A CG 1 ATOM 5310 C CD1 . PHE A 1 674 ? -35.286 -15.039 46.369 1.00 18.14 ? 694 PHE A CD1 1 ATOM 5311 C CD2 . PHE A 1 674 ? -34.231 -15.444 48.452 1.00 18.23 ? 694 PHE A CD2 1 ATOM 5312 C CE1 . PHE A 1 674 ? -36.484 -14.740 47.023 1.00 18.54 ? 694 PHE A CE1 1 ATOM 5313 C CE2 . PHE A 1 674 ? -35.418 -15.151 49.113 1.00 18.65 ? 694 PHE A CE2 1 ATOM 5314 C CZ . PHE A 1 674 ? -36.546 -14.790 48.391 1.00 17.67 ? 694 PHE A CZ 1 ATOM 5315 N N . LEU A 1 675 ? -32.764 -13.786 43.998 1.00 19.70 ? 695 LEU A N 1 ATOM 5316 C CA . LEU A 1 675 ? -33.442 -12.930 43.038 1.00 20.14 ? 695 LEU A CA 1 ATOM 5317 C C . LEU A 1 675 ? -34.623 -13.668 42.420 1.00 19.88 ? 695 LEU A C 1 ATOM 5318 O O . LEU A 1 675 ? -34.568 -14.879 42.212 1.00 19.88 ? 695 LEU A O 1 ATOM 5319 C CB . LEU A 1 675 ? -32.493 -12.511 41.916 1.00 20.91 ? 695 LEU A CB 1 ATOM 5320 C CG . LEU A 1 675 ? -31.440 -11.467 42.273 1.00 22.94 ? 695 LEU A CG 1 ATOM 5321 C CD1 . LEU A 1 675 ? -30.291 -12.117 43.010 1.00 25.16 ? 695 LEU A CD1 1 ATOM 5322 C CD2 . LEU A 1 675 ? -30.961 -10.762 41.022 1.00 24.94 ? 695 LEU A CD2 1 ATOM 5323 N N . LEU A 1 676 ? -35.694 -12.931 42.154 1.00 19.64 ? 696 LEU A N 1 ATOM 5324 C CA . LEU A 1 676 ? -36.805 -13.418 41.355 1.00 19.66 ? 696 LEU A CA 1 ATOM 5325 C C . LEU A 1 676 ? -36.795 -12.593 40.078 1.00 19.85 ? 696 LEU A C 1 ATOM 5326 O O . LEU A 1 676 ? -36.868 -11.367 40.130 1.00 20.32 ? 696 LEU A O 1 ATOM 5327 C CB . LEU A 1 676 ? -38.115 -13.263 42.110 1.00 19.61 ? 696 LEU A CB 1 ATOM 5328 C CG . LEU A 1 676 ? -38.170 -14.031 43.436 1.00 20.51 ? 696 LEU A CG 1 ATOM 5329 C CD1 . LEU A 1 676 ? -39.439 -13.696 44.203 1.00 20.12 ? 696 LEU A CD1 1 ATOM 5330 C CD2 . LEU A 1 676 ? -38.054 -15.537 43.204 1.00 20.02 ? 696 LEU A CD2 1 ATOM 5331 N N . ARG A 1 677 ? -36.656 -13.271 38.943 1.00 19.86 ? 697 ARG A N 1 ATOM 5332 C CA A ARG A 1 677 ? -36.463 -12.637 37.646 0.60 19.81 ? 697 ARG A CA 1 ATOM 5333 C CA B ARG A 1 677 ? -36.519 -12.591 37.674 0.40 19.93 ? 697 ARG A CA 1 ATOM 5334 C C . ARG A 1 677 ? -37.496 -13.163 36.654 1.00 19.94 ? 697 ARG A C 1 ATOM 5335 O O . ARG A 1 677 ? -37.666 -14.390 36.541 1.00 19.52 ? 697 ARG A O 1 ATOM 5336 C CB A ARG A 1 677 ? -35.078 -12.985 37.090 0.60 19.75 ? 697 ARG A CB 1 ATOM 5337 C CB B ARG A 1 677 ? -35.070 -12.640 37.162 0.40 20.01 ? 697 ARG A CB 1 ATOM 5338 C CG A ARG A 1 677 ? -33.922 -12.731 38.030 0.60 19.98 ? 697 ARG A CG 1 ATOM 5339 C CG B ARG A 1 677 ? -34.615 -13.965 36.591 0.40 20.58 ? 697 ARG A CG 1 ATOM 5340 C CD A ARG A 1 677 ? -32.596 -13.200 37.431 0.60 20.73 ? 697 ARG A CD 1 ATOM 5341 C CD B ARG A 1 677 ? -33.452 -13.785 35.642 0.40 21.75 ? 697 ARG A CD 1 ATOM 5342 N NE A ARG A 1 677 ? -32.290 -12.584 36.139 0.60 20.85 ? 697 ARG A NE 1 ATOM 5343 N NE B ARG A 1 677 ? -32.186 -13.569 36.332 0.40 22.36 ? 697 ARG A NE 1 ATOM 5344 C CZ A ARG A 1 677 ? -31.158 -12.776 35.458 0.60 22.03 ? 697 ARG A CZ 1 ATOM 5345 C CZ B ARG A 1 677 ? -31.039 -13.330 35.706 0.40 23.31 ? 697 ARG A CZ 1 ATOM 5346 N NH1 A ARG A 1 677 ? -30.190 -13.557 35.942 0.60 21.91 ? 697 ARG A NH1 1 ATOM 5347 N NH1 B ARG A 1 677 ? -31.014 -13.269 34.382 0.40 23.59 ? 697 ARG A NH1 1 ATOM 5348 N NH2 A ARG A 1 677 ? -30.983 -12.174 34.286 0.60 21.87 ? 697 ARG A NH2 1 ATOM 5349 N NH2 B ARG A 1 677 ? -29.920 -13.148 36.393 0.40 23.43 ? 697 ARG A NH2 1 ATOM 5350 N N . PRO A 1 678 ? -38.166 -12.260 35.911 1.00 19.95 ? 698 PRO A N 1 ATOM 5351 C CA . PRO A 1 678 ? -39.115 -12.757 34.917 1.00 19.77 ? 698 PRO A CA 1 ATOM 5352 C C . PRO A 1 678 ? -38.388 -13.504 33.792 1.00 19.56 ? 698 PRO A C 1 ATOM 5353 O O . PRO A 1 678 ? -37.278 -13.136 33.386 1.00 20.04 ? 698 PRO A O 1 ATOM 5354 C CB . PRO A 1 678 ? -39.813 -11.492 34.413 1.00 19.63 ? 698 PRO A CB 1 ATOM 5355 C CG . PRO A 1 678 ? -38.869 -10.379 34.701 1.00 20.51 ? 698 PRO A CG 1 ATOM 5356 C CD . PRO A 1 678 ? -38.040 -10.791 35.888 1.00 19.99 ? 698 PRO A CD 1 ATOM 5357 N N . PHE A 1 679 ? -39.011 -14.570 33.324 1.00 18.94 ? 699 PHE A N 1 ATOM 5358 C CA . PHE A 1 679 ? -38.426 -15.432 32.307 1.00 18.68 ? 699 PHE A CA 1 ATOM 5359 C C . PHE A 1 679 ? -39.567 -15.808 31.380 1.00 18.57 ? 699 PHE A C 1 ATOM 5360 O O . PHE A 1 679 ? -40.396 -16.675 31.700 1.00 18.34 ? 699 PHE A O 1 ATOM 5361 C CB . PHE A 1 679 ? -37.784 -16.671 32.948 1.00 18.55 ? 699 PHE A CB 1 ATOM 5362 C CG . PHE A 1 679 ? -37.082 -17.547 31.973 1.00 17.22 ? 699 PHE A CG 1 ATOM 5363 C CD1 . PHE A 1 679 ? -35.750 -17.323 31.657 1.00 17.37 ? 699 PHE A CD1 1 ATOM 5364 C CD2 . PHE A 1 679 ? -37.753 -18.587 31.350 1.00 16.95 ? 699 PHE A CD2 1 ATOM 5365 C CE1 . PHE A 1 679 ? -35.091 -18.140 30.727 1.00 17.37 ? 699 PHE A CE1 1 ATOM 5366 C CE2 . PHE A 1 679 ? -37.107 -19.395 30.421 1.00 18.15 ? 699 PHE A CE2 1 ATOM 5367 C CZ . PHE A 1 679 ? -35.765 -19.168 30.116 1.00 16.36 ? 699 PHE A CZ 1 ATOM 5368 N N . ASN A 1 680 ? -39.628 -15.097 30.258 1.00 18.85 ? 700 ASN A N 1 ATOM 5369 C CA . ASN A 1 680 ? -40.700 -15.231 29.259 1.00 18.75 ? 700 ASN A CA 1 ATOM 5370 C C . ASN A 1 680 ? -42.067 -14.826 29.812 1.00 18.61 ? 700 ASN A C 1 ATOM 5371 O O . ASN A 1 680 ? -43.116 -15.223 29.293 1.00 18.37 ? 700 ASN A O 1 ATOM 5372 C CB . ASN A 1 680 ? -40.733 -16.640 28.670 1.00 18.68 ? 700 ASN A CB 1 ATOM 5373 C CG . ASN A 1 680 ? -39.457 -16.994 27.926 1.00 19.19 ? 700 ASN A CG 1 ATOM 5374 O OD1 . ASN A 1 680 ? -38.941 -16.199 27.139 1.00 17.50 ? 700 ASN A OD1 1 ATOM 5375 N ND2 . ASN A 1 680 ? -38.964 -18.207 28.147 1.00 18.14 ? 700 ASN A ND2 1 ATOM 5376 N N . PHE A 1 681 ? -42.036 -14.010 30.858 1.00 18.86 ? 701 PHE A N 1 ATOM 5377 C CA . PHE A 1 681 ? -43.246 -13.522 31.492 1.00 18.91 ? 701 PHE A CA 1 ATOM 5378 C C . PHE A 1 681 ? -43.835 -12.370 30.689 1.00 18.78 ? 701 PHE A C 1 ATOM 5379 O O . PHE A 1 681 ? -45.034 -12.340 30.438 1.00 18.46 ? 701 PHE A O 1 ATOM 5380 C CB . PHE A 1 681 ? -42.941 -13.068 32.910 1.00 19.00 ? 701 PHE A CB 1 ATOM 5381 C CG . PHE A 1 681 ? -44.166 -12.802 33.742 1.00 19.90 ? 701 PHE A CG 1 ATOM 5382 C CD1 . PHE A 1 681 ? -44.743 -11.542 33.767 1.00 21.48 ? 701 PHE A CD1 1 ATOM 5383 C CD2 . PHE A 1 681 ? -44.734 -13.807 34.503 1.00 20.90 ? 701 PHE A CD2 1 ATOM 5384 C CE1 . PHE A 1 681 ? -45.854 -11.284 34.547 1.00 21.40 ? 701 PHE A CE1 1 ATOM 5385 C CE2 . PHE A 1 681 ? -45.847 -13.555 35.284 1.00 21.18 ? 701 PHE A CE2 1 ATOM 5386 C CZ . PHE A 1 681 ? -46.405 -12.294 35.305 1.00 21.45 ? 701 PHE A CZ 1 ATOM 5387 N N . PHE A 1 682 ? -42.979 -11.430 30.306 1.00 18.93 ? 702 PHE A N 1 ATOM 5388 C CA . PHE A 1 682 ? -43.382 -10.244 29.553 1.00 19.63 ? 702 PHE A CA 1 ATOM 5389 C C . PHE A 1 682 ? -42.964 -10.390 28.082 1.00 19.56 ? 702 PHE A C 1 ATOM 5390 O O . PHE A 1 682 ? -42.014 -11.112 27.783 1.00 19.90 ? 702 PHE A O 1 ATOM 5391 C CB . PHE A 1 682 ? -42.729 -8.990 30.151 1.00 19.81 ? 702 PHE A CB 1 ATOM 5392 C CG . PHE A 1 682 ? -43.022 -8.779 31.620 1.00 21.04 ? 702 PHE A CG 1 ATOM 5393 C CD1 . PHE A 1 682 ? -42.073 -9.094 32.587 1.00 21.87 ? 702 PHE A CD1 1 ATOM 5394 C CD2 . PHE A 1 682 ? -44.243 -8.264 32.033 1.00 21.60 ? 702 PHE A CD2 1 ATOM 5395 C CE1 . PHE A 1 682 ? -42.334 -8.895 33.939 1.00 21.98 ? 702 PHE A CE1 1 ATOM 5396 C CE2 . PHE A 1 682 ? -44.509 -8.062 33.384 1.00 21.98 ? 702 PHE A CE2 1 ATOM 5397 C CZ . PHE A 1 682 ? -43.556 -8.374 34.333 1.00 22.24 ? 702 PHE A CZ 1 ATOM 5398 N N . PRO A 1 683 ? -43.657 -9.695 27.159 1.00 19.61 ? 703 PRO A N 1 ATOM 5399 C CA . PRO A 1 683 ? -43.330 -9.813 25.726 1.00 19.57 ? 703 PRO A CA 1 ATOM 5400 C C . PRO A 1 683 ? -41.935 -9.311 25.340 1.00 19.11 ? 703 PRO A C 1 ATOM 5401 O O . PRO A 1 683 ? -41.366 -9.774 24.353 1.00 18.92 ? 703 PRO A O 1 ATOM 5402 C CB . PRO A 1 683 ? -44.392 -8.949 25.044 1.00 19.66 ? 703 PRO A CB 1 ATOM 5403 C CG . PRO A 1 683 ? -45.455 -8.763 26.054 1.00 20.06 ? 703 PRO A CG 1 ATOM 5404 C CD . PRO A 1 683 ? -44.809 -8.806 27.383 1.00 19.66 ? 703 PRO A CD 1 ATOM 5405 N N . GLU A 1 684 ? -41.416 -8.362 26.116 1.00 19.04 ? 704 GLU A N 1 ATOM 5406 C CA . GLU A 1 684 ? -40.081 -7.780 25.915 1.00 18.75 ? 704 GLU A CA 1 ATOM 5407 C C . GLU A 1 684 ? -39.695 -7.123 27.238 1.00 18.37 ? 704 GLU A C 1 ATOM 5408 O O . GLU A 1 684 ? -40.474 -7.186 28.206 1.00 17.91 ? 704 GLU A O 1 ATOM 5409 C CB . GLU A 1 684 ? -40.095 -6.757 24.762 1.00 19.08 ? 704 GLU A CB 1 ATOM 5410 C CG . GLU A 1 684 ? -41.256 -5.756 24.857 1.00 19.68 ? 704 GLU A CG 1 ATOM 5411 C CD . GLU A 1 684 ? -41.257 -4.692 23.765 1.00 21.14 ? 704 GLU A CD 1 ATOM 5412 O OE1 . GLU A 1 684 ? -40.627 -4.890 22.698 1.00 21.55 ? 704 GLU A OE1 1 ATOM 5413 O OE2 . GLU A 1 684 ? -41.912 -3.650 23.979 1.00 20.34 ? 704 GLU A OE2 1 ATOM 5414 N N . ASP A 1 685 ? -38.506 -6.519 27.293 1.00 17.72 ? 705 ASP A N 1 ATOM 5415 C CA . ASP A 1 685 ? -37.995 -5.876 28.516 1.00 17.64 ? 705 ASP A CA 1 ATOM 5416 C C . ASP A 1 685 ? -39.040 -4.972 29.205 1.00 17.41 ? 705 ASP A C 1 ATOM 5417 O O . ASP A 1 685 ? -39.400 -3.929 28.671 1.00 17.52 ? 705 ASP A O 1 ATOM 5418 C CB . ASP A 1 685 ? -36.749 -5.070 28.174 1.00 17.41 ? 705 ASP A CB 1 ATOM 5419 C CG . ASP A 1 685 ? -36.200 -4.273 29.353 1.00 18.43 ? 705 ASP A CG 1 ATOM 5420 O OD1 . ASP A 1 685 ? -36.673 -4.424 30.503 1.00 17.22 ? 705 ASP A OD1 1 ATOM 5421 O OD2 . ASP A 1 685 ? -35.269 -3.473 29.111 1.00 19.82 ? 705 ASP A OD2 1 ATOM 5422 N N . PRO A 1 686 ? -39.516 -5.362 30.403 1.00 17.49 ? 706 PRO A N 1 ATOM 5423 C CA . PRO A 1 686 ? -40.589 -4.574 31.025 1.00 18.00 ? 706 PRO A CA 1 ATOM 5424 C C . PRO A 1 686 ? -40.165 -3.158 31.440 1.00 18.46 ? 706 PRO A C 1 ATOM 5425 O O . PRO A 1 686 ? -41.028 -2.321 31.678 1.00 18.65 ? 706 PRO A O 1 ATOM 5426 C CB . PRO A 1 686 ? -41.001 -5.429 32.240 1.00 18.14 ? 706 PRO A CB 1 ATOM 5427 C CG . PRO A 1 686 ? -39.859 -6.274 32.526 1.00 17.34 ? 706 PRO A CG 1 ATOM 5428 C CD . PRO A 1 686 ? -39.173 -6.543 31.218 1.00 17.34 ? 706 PRO A CD 1 ATOM 5429 N N . SER A 1 687 ? -38.855 -2.889 31.484 1.00 18.73 ? 707 SER A N 1 ATOM 5430 C CA . SER A 1 687 ? -38.350 -1.554 31.788 1.00 18.98 ? 707 SER A CA 1 ATOM 5431 C C . SER A 1 687 ? -38.461 -0.596 30.602 1.00 19.29 ? 707 SER A C 1 ATOM 5432 O O . SER A 1 687 ? -38.159 0.575 30.737 1.00 19.22 ? 707 SER A O 1 ATOM 5433 C CB . SER A 1 687 ? -36.886 -1.604 32.270 1.00 18.98 ? 707 SER A CB 1 ATOM 5434 O OG . SER A 1 687 ? -35.988 -1.686 31.182 1.00 17.68 ? 707 SER A OG 1 ATOM 5435 N N . LEU A 1 688 ? -38.894 -1.082 29.443 1.00 19.80 ? 708 LEU A N 1 ATOM 5436 C CA . LEU A 1 688 ? -39.084 -0.211 28.285 1.00 19.91 ? 708 LEU A CA 1 ATOM 5437 C C . LEU A 1 688 ? -40.084 0.933 28.496 1.00 20.38 ? 708 LEU A C 1 ATOM 5438 O O . LEU A 1 688 ? -40.019 1.938 27.789 1.00 19.68 ? 708 LEU A O 1 ATOM 5439 C CB . LEU A 1 688 ? -39.471 -1.025 27.056 1.00 20.01 ? 708 LEU A CB 1 ATOM 5440 C CG . LEU A 1 688 ? -38.311 -1.823 26.455 1.00 20.22 ? 708 LEU A CG 1 ATOM 5441 C CD1 . LEU A 1 688 ? -38.835 -2.848 25.456 1.00 20.48 ? 708 LEU A CD1 1 ATOM 5442 C CD2 . LEU A 1 688 ? -37.252 -0.907 25.825 1.00 18.91 ? 708 LEU A CD2 1 ATOM 5443 N N . ALA A 1 689 ? -40.996 0.792 29.457 1.00 20.88 ? 709 ALA A N 1 ATOM 5444 C CA . ALA A 1 689 ? -41.928 1.877 29.783 1.00 21.26 ? 709 ALA A CA 1 ATOM 5445 C C . ALA A 1 689 ? -41.264 3.019 30.565 1.00 21.49 ? 709 ALA A C 1 ATOM 5446 O O . ALA A 1 689 ? -41.857 4.089 30.708 1.00 21.24 ? 709 ALA A O 1 ATOM 5447 C CB . ALA A 1 689 ? -43.143 1.330 30.560 1.00 21.67 ? 709 ALA A CB 1 ATOM 5448 N N . SER A 1 690 ? -40.048 2.797 31.077 1.00 21.71 ? 710 SER A N 1 ATOM 5449 C CA . SER A 1 690 ? -39.305 3.848 31.760 1.00 21.86 ? 710 SER A CA 1 ATOM 5450 C C . SER A 1 690 ? -39.000 4.990 30.798 1.00 22.12 ? 710 SER A C 1 ATOM 5451 O O . SER A 1 690 ? -38.495 4.766 29.708 1.00 22.61 ? 710 SER A O 1 ATOM 5452 C CB . SER A 1 690 ? -37.990 3.319 32.355 1.00 21.97 ? 710 SER A CB 1 ATOM 5453 O OG . SER A 1 690 ? -37.202 4.382 32.913 1.00 21.41 ? 710 SER A OG 1 ATOM 5454 N N . ARG A 1 691 ? -39.294 6.215 31.214 1.00 22.54 ? 711 ARG A N 1 ATOM 5455 C CA . ARG A 1 691 ? -38.978 7.382 30.405 1.00 23.16 ? 711 ARG A CA 1 ATOM 5456 C C . ARG A 1 691 ? -37.599 7.984 30.723 1.00 22.67 ? 711 ARG A C 1 ATOM 5457 O O . ARG A 1 691 ? -37.235 9.006 30.158 1.00 22.95 ? 711 ARG A O 1 ATOM 5458 C CB . ARG A 1 691 ? -40.089 8.430 30.516 1.00 23.47 ? 711 ARG A CB 1 ATOM 5459 C CG . ARG A 1 691 ? -41.474 7.979 30.006 1.00 25.86 ? 711 ARG A CG 1 ATOM 5460 C CD . ARG A 1 691 ? -41.388 7.070 28.782 1.00 29.12 ? 711 ARG A CD 1 ATOM 5461 N NE . ARG A 1 691 ? -42.591 7.000 27.931 1.00 32.07 ? 711 ARG A NE 1 ATOM 5462 C CZ . ARG A 1 691 ? -43.419 5.954 27.811 1.00 34.36 ? 711 ARG A CZ 1 ATOM 5463 N NH1 . ARG A 1 691 ? -43.263 4.855 28.535 1.00 36.01 ? 711 ARG A NH1 1 ATOM 5464 N NH2 . ARG A 1 691 ? -44.437 6.009 26.956 1.00 34.82 ? 711 ARG A NH2 1 ATOM 5465 N N . ASP A 1 692 ? -36.824 7.328 31.581 1.00 22.27 ? 712 ASP A N 1 ATOM 5466 C CA . ASP A 1 692 ? -35.478 7.779 31.926 1.00 22.21 ? 712 ASP A CA 1 ATOM 5467 C C . ASP A 1 692 ? -34.443 7.415 30.882 1.00 21.61 ? 712 ASP A C 1 ATOM 5468 O O . ASP A 1 692 ? -33.328 7.913 30.937 1.00 20.55 ? 712 ASP A O 1 ATOM 5469 C CB . ASP A 1 692 ? -35.030 7.157 33.244 1.00 22.90 ? 712 ASP A CB 1 ATOM 5470 C CG . ASP A 1 692 ? -35.882 7.578 34.395 1.00 24.45 ? 712 ASP A CG 1 ATOM 5471 O OD1 . ASP A 1 692 ? -36.261 8.763 34.451 1.00 29.11 ? 712 ASP A OD1 1 ATOM 5472 O OD2 . ASP A 1 692 ? -36.160 6.724 35.252 1.00 27.97 ? 712 ASP A OD2 1 ATOM 5473 N N . THR A 1 693 ? -34.801 6.519 29.959 1.00 21.38 ? 713 THR A N 1 ATOM 5474 C CA . THR A 1 693 ? -33.900 6.111 28.890 1.00 21.25 ? 713 THR A CA 1 ATOM 5475 C C . THR A 1 693 ? -33.401 7.319 28.082 1.00 21.34 ? 713 THR A C 1 ATOM 5476 O O . THR A 1 693 ? -34.152 8.240 27.778 1.00 20.97 ? 713 THR A O 1 ATOM 5477 C CB . THR A 1 693 ? -34.583 5.122 27.942 1.00 21.30 ? 713 THR A CB 1 ATOM 5478 O OG1 . THR A 1 693 ? -35.041 3.993 28.695 1.00 21.30 ? 713 THR A OG1 1 ATOM 5479 C CG2 . THR A 1 693 ? -33.613 4.657 26.842 1.00 20.40 ? 713 THR A CG2 1 ATOM 5480 N N . VAL A 1 694 ? -32.118 7.305 27.752 1.00 21.46 ? 714 VAL A N 1 ATOM 5481 C CA . VAL A 1 694 ? -31.542 8.340 26.911 1.00 21.40 ? 714 VAL A CA 1 ATOM 5482 C C . VAL A 1 694 ? -30.886 7.686 25.702 1.00 21.31 ? 714 VAL A C 1 ATOM 5483 O O . VAL A 1 694 ? -30.190 6.677 25.846 1.00 21.29 ? 714 VAL A O 1 ATOM 5484 C CB . VAL A 1 694 ? -30.521 9.168 27.727 1.00 21.57 ? 714 VAL A CB 1 ATOM 5485 C CG1 . VAL A 1 694 ? -29.732 10.109 26.827 1.00 21.31 ? 714 VAL A CG1 1 ATOM 5486 C CG2 . VAL A 1 694 ? -31.261 9.940 28.850 1.00 20.69 ? 714 VAL A CG2 1 ATOM 5487 N N . ILE A 1 695 ? -31.121 8.254 24.520 1.00 20.86 ? 715 ILE A N 1 ATOM 5488 C CA . ILE A 1 695 ? -30.460 7.815 23.294 1.00 20.82 ? 715 ILE A CA 1 ATOM 5489 C C . ILE A 1 695 ? -29.796 9.018 22.621 1.00 21.22 ? 715 ILE A C 1 ATOM 5490 O O . ILE A 1 695 ? -30.459 10.026 22.354 1.00 21.48 ? 715 ILE A O 1 ATOM 5491 C CB . ILE A 1 695 ? -31.447 7.156 22.277 1.00 20.69 ? 715 ILE A CB 1 ATOM 5492 C CG1 . ILE A 1 695 ? -32.371 6.139 22.957 1.00 19.77 ? 715 ILE A CG1 1 ATOM 5493 C CG2 . ILE A 1 695 ? -30.664 6.474 21.152 1.00 19.96 ? 715 ILE A CG2 1 ATOM 5494 C CD1 . ILE A 1 695 ? -33.360 5.461 21.993 1.00 18.30 ? 715 ILE A CD1 1 ATOM 5495 N N . VAL A 1 696 ? -28.494 8.909 22.366 1.00 21.55 ? 716 VAL A N 1 ATOM 5496 C CA . VAL A 1 696 ? -27.731 9.939 21.659 1.00 21.80 ? 716 VAL A CA 1 ATOM 5497 C C . VAL A 1 696 ? -27.527 9.494 20.218 1.00 22.81 ? 716 VAL A C 1 ATOM 5498 O O . VAL A 1 696 ? -27.059 8.377 19.976 1.00 22.35 ? 716 VAL A O 1 ATOM 5499 C CB . VAL A 1 696 ? -26.351 10.166 22.284 1.00 22.04 ? 716 VAL A CB 1 ATOM 5500 C CG1 . VAL A 1 696 ? -25.608 11.307 21.556 1.00 20.25 ? 716 VAL A CG1 1 ATOM 5501 C CG2 . VAL A 1 696 ? -26.468 10.450 23.788 1.00 21.27 ? 716 VAL A CG2 1 ATOM 5502 N N . TRP A 1 697 ? -27.872 10.377 19.280 1.00 23.78 ? 717 TRP A N 1 ATOM 5503 C CA . TRP A 1 697 ? -27.815 10.096 17.856 1.00 25.18 ? 717 TRP A CA 1 ATOM 5504 C C . TRP A 1 697 ? -26.861 11.073 17.155 1.00 26.38 ? 717 TRP A C 1 ATOM 5505 O O . TRP A 1 697 ? -26.877 12.265 17.451 1.00 26.24 ? 717 TRP A O 1 ATOM 5506 C CB . TRP A 1 697 ? -29.199 10.283 17.239 1.00 25.26 ? 717 TRP A CB 1 ATOM 5507 C CG . TRP A 1 697 ? -30.296 9.485 17.856 1.00 25.49 ? 717 TRP A CG 1 ATOM 5508 C CD1 . TRP A 1 697 ? -31.105 9.870 18.873 1.00 26.15 ? 717 TRP A CD1 1 ATOM 5509 C CD2 . TRP A 1 697 ? -30.738 8.180 17.460 1.00 25.40 ? 717 TRP A CD2 1 ATOM 5510 N NE1 . TRP A 1 697 ? -32.015 8.882 19.155 1.00 25.80 ? 717 TRP A NE1 1 ATOM 5511 C CE2 . TRP A 1 697 ? -31.812 7.833 18.300 1.00 25.46 ? 717 TRP A CE2 1 ATOM 5512 C CE3 . TRP A 1 697 ? -30.325 7.269 16.478 1.00 25.79 ? 717 TRP A CE3 1 ATOM 5513 C CZ2 . TRP A 1 697 ? -32.488 6.610 18.195 1.00 25.94 ? 717 TRP A CZ2 1 ATOM 5514 C CZ3 . TRP A 1 697 ? -30.992 6.050 16.375 1.00 25.82 ? 717 TRP A CZ3 1 ATOM 5515 C CH2 . TRP A 1 697 ? -32.061 5.735 17.230 1.00 26.43 ? 717 TRP A CH2 1 ATOM 5516 N N . PRO A 1 698 ? -26.049 10.583 16.206 1.00 27.69 ? 718 PRO A N 1 ATOM 5517 C CA . PRO A 1 698 ? -25.201 11.504 15.457 1.00 29.03 ? 718 PRO A CA 1 ATOM 5518 C C . PRO A 1 698 ? -25.987 12.337 14.437 1.00 30.28 ? 718 PRO A C 1 ATOM 5519 O O . PRO A 1 698 ? -27.055 11.926 14.002 1.00 30.00 ? 718 PRO A O 1 ATOM 5520 C CB . PRO A 1 698 ? -24.247 10.563 14.721 1.00 28.74 ? 718 PRO A CB 1 ATOM 5521 C CG . PRO A 1 698 ? -25.115 9.382 14.412 1.00 28.24 ? 718 PRO A CG 1 ATOM 5522 C CD . PRO A 1 698 ? -25.980 9.219 15.655 1.00 27.86 ? 718 PRO A CD 1 ATOM 5523 N N . ARG A 1 699 ? -25.442 13.498 14.085 1.00 31.95 ? 719 ARG A N 1 ATOM 5524 C CA A ARG A 1 699 ? -26.010 14.359 13.050 0.60 32.86 ? 719 ARG A CA 1 ATOM 5525 C CA B ARG A 1 699 ? -26.005 14.355 13.038 0.40 32.73 ? 719 ARG A CA 1 ATOM 5526 C C . ARG A 1 699 ? -24.876 14.827 12.139 1.00 33.53 ? 719 ARG A C 1 ATOM 5527 O O . ARG A 1 699 ? -23.820 15.212 12.623 1.00 33.49 ? 719 ARG A O 1 ATOM 5528 C CB A ARG A 1 699 ? -26.706 15.570 13.682 0.60 32.92 ? 719 ARG A CB 1 ATOM 5529 C CB B ARG A 1 699 ? -26.709 15.570 13.643 0.40 32.71 ? 719 ARG A CB 1 ATOM 5530 C CG A ARG A 1 699 ? -27.963 15.238 14.499 0.60 33.24 ? 719 ARG A CG 1 ATOM 5531 C CG B ARG A 1 699 ? -28.072 15.270 14.225 0.40 32.59 ? 719 ARG A CG 1 ATOM 5532 C CD A ARG A 1 699 ? -29.131 14.906 13.595 0.60 33.94 ? 719 ARG A CD 1 ATOM 5533 C CD B ARG A 1 699 ? -28.301 16.063 15.488 0.40 32.51 ? 719 ARG A CD 1 ATOM 5534 N NE A ARG A 1 699 ? -30.389 14.693 14.318 0.60 34.15 ? 719 ARG A NE 1 ATOM 5535 N NE B ARG A 1 699 ? -28.836 17.396 15.245 0.40 32.56 ? 719 ARG A NE 1 ATOM 5536 C CZ A ARG A 1 699 ? -30.955 13.510 14.564 0.60 34.28 ? 719 ARG A CZ 1 ATOM 5537 C CZ B ARG A 1 699 ? -28.908 18.350 16.168 0.40 31.79 ? 719 ARG A CZ 1 ATOM 5538 N NH1 A ARG A 1 699 ? -30.393 12.371 14.171 0.60 34.44 ? 719 ARG A NH1 1 ATOM 5539 N NH1 B ARG A 1 699 ? -28.459 18.126 17.388 0.40 31.30 ? 719 ARG A NH1 1 ATOM 5540 N NH2 A ARG A 1 699 ? -32.106 13.464 15.222 0.60 35.22 ? 719 ARG A NH2 1 ATOM 5541 N NH2 B ARG A 1 699 ? -29.419 19.535 15.867 0.40 32.06 ? 719 ARG A NH2 1 ATOM 5542 N N . ASP A 1 700 ? -25.097 14.792 10.829 1.00 35.04 ? 720 ASP A N 1 ATOM 5543 C CA . ASP A 1 700 ? -24.052 15.196 9.875 1.00 36.52 ? 720 ASP A CA 1 ATOM 5544 C C . ASP A 1 700 ? -23.708 16.664 10.014 1.00 36.91 ? 720 ASP A C 1 ATOM 5545 O O . ASP A 1 700 ? -24.587 17.512 9.934 1.00 37.77 ? 720 ASP A O 1 ATOM 5546 C CB . ASP A 1 700 ? -24.477 14.891 8.443 1.00 36.87 ? 720 ASP A CB 1 ATOM 5547 C CG . ASP A 1 700 ? -24.403 13.420 8.122 1.00 39.04 ? 720 ASP A CG 1 ATOM 5548 O OD1 . ASP A 1 700 ? -23.944 12.639 8.991 1.00 42.27 ? 720 ASP A OD1 1 ATOM 5549 O OD2 . ASP A 1 700 ? -24.795 13.039 6.993 1.00 42.68 ? 720 ASP A OD2 1 ATOM 5550 N N . ASN A 1 701 ? -22.431 16.948 10.256 1.00 37.41 ? 721 ASN A N 1 ATOM 5551 C CA . ASN A 1 701 ? -21.932 18.320 10.395 1.00 37.57 ? 721 ASN A CA 1 ATOM 5552 C C . ASN A 1 701 ? -22.556 19.111 11.549 1.00 37.19 ? 721 ASN A C 1 ATOM 5553 O O . ASN A 1 701 ? -22.691 20.329 11.454 1.00 37.63 ? 721 ASN A O 1 ATOM 5554 C CB . ASN A 1 701 ? -22.138 19.092 9.087 1.00 37.99 ? 721 ASN A CB 1 ATOM 5555 C CG . ASN A 1 701 ? -21.689 18.310 7.874 1.00 39.25 ? 721 ASN A CG 1 ATOM 5556 O OD1 . ASN A 1 701 ? -20.504 17.996 7.733 1.00 42.33 ? 721 ASN A OD1 1 ATOM 5557 N ND2 . ASN A 1 701 ? -22.631 17.986 6.990 1.00 40.28 ? 721 ASN A ND2 1 ATOM 5558 N N . GLY A 1 702 ? -22.927 18.432 12.632 1.00 36.32 ? 722 GLY A N 1 ATOM 5559 C CA . GLY A 1 702 ? -23.491 19.105 13.809 1.00 35.59 ? 722 GLY A CA 1 ATOM 5560 C C . GLY A 1 702 ? -23.238 18.347 15.109 1.00 34.85 ? 722 GLY A C 1 ATOM 5561 O O . GLY A 1 702 ? -22.696 17.242 15.091 1.00 34.61 ? 722 GLY A O 1 ATOM 5562 N N . PRO A 1 703 ? -23.615 18.945 16.254 1.00 33.79 ? 723 PRO A N 1 ATOM 5563 C CA . PRO A 1 703 ? -23.556 18.206 17.509 1.00 33.04 ? 723 PRO A CA 1 ATOM 5564 C C . PRO A 1 703 ? -24.587 17.083 17.496 1.00 31.88 ? 723 PRO A C 1 ATOM 5565 O O . PRO A 1 703 ? -25.497 17.108 16.675 1.00 31.70 ? 723 PRO A O 1 ATOM 5566 C CB . PRO A 1 703 ? -23.907 19.257 18.577 1.00 33.22 ? 723 PRO A CB 1 ATOM 5567 C CG . PRO A 1 703 ? -23.963 20.574 17.865 1.00 33.72 ? 723 PRO A CG 1 ATOM 5568 C CD . PRO A 1 703 ? -24.188 20.289 16.426 1.00 33.90 ? 723 PRO A CD 1 ATOM 5569 N N . ASN A 1 704 ? -24.431 16.106 18.383 1.00 30.54 ? 724 ASN A N 1 ATOM 5570 C CA . ASN A 1 704 ? -25.363 14.976 18.449 1.00 29.60 ? 724 ASN A CA 1 ATOM 5571 C C . ASN A 1 704 ? -26.736 15.424 18.960 1.00 28.94 ? 724 ASN A C 1 ATOM 5572 O O . ASN A 1 704 ? -26.842 16.410 19.670 1.00 28.98 ? 724 ASN A O 1 ATOM 5573 C CB . ASN A 1 704 ? -24.788 13.870 19.342 1.00 28.92 ? 724 ASN A CB 1 ATOM 5574 C CG . ASN A 1 704 ? -23.478 13.298 18.801 1.00 28.60 ? 724 ASN A CG 1 ATOM 5575 O OD1 . ASN A 1 704 ? -23.343 13.060 17.605 1.00 26.26 ? 724 ASN A OD1 1 ATOM 5576 N ND2 . ASN A 1 704 ? -22.512 13.074 19.687 1.00 27.38 ? 724 ASN A ND2 1 ATOM 5577 N N . TYR A 1 705 ? -27.786 14.722 18.562 1.00 28.40 ? 725 TYR A N 1 ATOM 5578 C CA . TYR A 1 705 ? -29.119 14.916 19.148 1.00 27.99 ? 725 TYR A CA 1 ATOM 5579 C C . TYR A 1 705 ? -29.284 13.978 20.345 1.00 27.01 ? 725 TYR A C 1 ATOM 5580 O O . TYR A 1 705 ? -29.298 12.763 20.181 1.00 26.39 ? 725 TYR A O 1 ATOM 5581 C CB . TYR A 1 705 ? -30.209 14.628 18.116 1.00 28.30 ? 725 TYR A CB 1 ATOM 5582 C CG . TYR A 1 705 ? -31.616 14.495 18.681 1.00 29.74 ? 725 TYR A CG 1 ATOM 5583 C CD1 . TYR A 1 705 ? -32.150 15.466 19.521 1.00 32.26 ? 725 TYR A CD1 1 ATOM 5584 C CD2 . TYR A 1 705 ? -32.417 13.409 18.352 1.00 31.86 ? 725 TYR A CD2 1 ATOM 5585 C CE1 . TYR A 1 705 ? -33.449 15.353 20.030 1.00 33.03 ? 725 TYR A CE1 1 ATOM 5586 C CE2 . TYR A 1 705 ? -33.714 13.287 18.855 1.00 33.29 ? 725 TYR A CE2 1 ATOM 5587 C CZ . TYR A 1 705 ? -34.219 14.265 19.693 1.00 34.05 ? 725 TYR A CZ 1 ATOM 5588 O OH . TYR A 1 705 ? -35.501 14.143 20.191 1.00 37.69 ? 725 TYR A OH 1 ATOM 5589 N N . VAL A 1 706 ? -29.392 14.545 21.544 1.00 26.18 ? 726 VAL A N 1 ATOM 5590 C CA . VAL A 1 706 ? -29.606 13.751 22.751 1.00 25.72 ? 726 VAL A CA 1 ATOM 5591 C C . VAL A 1 706 ? -31.111 13.600 22.964 1.00 25.34 ? 726 VAL A C 1 ATOM 5592 O O . VAL A 1 706 ? -31.775 14.532 23.410 1.00 25.57 ? 726 VAL A O 1 ATOM 5593 C CB . VAL A 1 706 ? -28.970 14.409 23.982 1.00 25.79 ? 726 VAL A CB 1 ATOM 5594 C CG1 . VAL A 1 706 ? -29.258 13.585 25.237 1.00 25.69 ? 726 VAL A CG1 1 ATOM 5595 C CG2 . VAL A 1 706 ? -27.463 14.596 23.773 1.00 24.99 ? 726 VAL A CG2 1 ATOM 5596 N N . GLN A 1 707 ? -31.646 12.435 22.615 1.00 24.86 ? 727 GLN A N 1 ATOM 5597 C CA . GLN A 1 707 ? -33.083 12.166 22.752 1.00 24.56 ? 727 GLN A CA 1 ATOM 5598 C C . GLN A 1 707 ? -33.432 11.785 24.201 1.00 24.55 ? 727 GLN A C 1 ATOM 5599 O O . GLN A 1 707 ? -32.888 10.831 24.746 1.00 24.01 ? 727 GLN A O 1 ATOM 5600 C CB . GLN A 1 707 ? -33.507 11.055 21.792 1.00 24.13 ? 727 GLN A CB 1 ATOM 5601 C CG . GLN A 1 707 ? -35.003 10.933 21.621 1.00 23.90 ? 727 GLN A CG 1 ATOM 5602 C CD . GLN A 1 707 ? -35.394 9.938 20.551 1.00 23.80 ? 727 GLN A CD 1 ATOM 5603 O OE1 . GLN A 1 707 ? -34.602 9.073 20.160 1.00 25.29 ? 727 GLN A OE1 1 ATOM 5604 N NE2 . GLN A 1 707 ? -36.627 10.038 20.082 1.00 21.22 ? 727 GLN A NE2 1 ATOM 5605 N N . ARG A 1 708 ? -34.341 12.550 24.802 1.00 25.02 ? 728 ARG A N 1 ATOM 5606 C CA . ARG A 1 708 ? -34.807 12.341 26.176 1.00 25.46 ? 728 ARG A CA 1 ATOM 5607 C C . ARG A 1 708 ? -36.320 12.242 26.187 1.00 25.49 ? 728 ARG A C 1 ATOM 5608 O O . ARG A 1 708 ? -36.972 12.713 25.263 1.00 25.26 ? 728 ARG A O 1 ATOM 5609 C CB . ARG A 1 708 ? -34.422 13.528 27.057 1.00 25.71 ? 728 ARG A CB 1 ATOM 5610 C CG . ARG A 1 708 ? -32.983 13.536 27.482 1.00 26.82 ? 728 ARG A CG 1 ATOM 5611 C CD . ARG A 1 708 ? -32.632 14.842 28.180 1.00 27.42 ? 728 ARG A CD 1 ATOM 5612 N NE . ARG A 1 708 ? -31.185 14.968 28.358 1.00 27.61 ? 728 ARG A NE 1 ATOM 5613 C CZ . ARG A 1 708 ? -30.480 14.331 29.290 1.00 28.10 ? 728 ARG A CZ 1 ATOM 5614 N NH1 . ARG A 1 708 ? -31.075 13.508 30.151 1.00 27.98 ? 728 ARG A NH1 1 ATOM 5615 N NH2 . ARG A 1 708 ? -29.165 14.519 29.368 1.00 29.13 ? 728 ARG A NH2 1 ATOM 5616 N N . TRP A 1 709 ? -36.869 11.625 27.231 1.00 25.45 ? 729 TRP A N 1 ATOM 5617 C CA . TRP A 1 709 ? -38.307 11.692 27.491 1.00 25.72 ? 729 TRP A CA 1 ATOM 5618 C C . TRP A 1 709 ? -38.608 12.290 28.875 1.00 26.32 ? 729 TRP A C 1 ATOM 5619 O O . TRP A 1 709 ? -39.770 12.399 29.271 1.00 26.73 ? 729 TRP A O 1 ATOM 5620 C CB . TRP A 1 709 ? -38.945 10.308 27.323 1.00 25.27 ? 729 TRP A CB 1 ATOM 5621 C CG . TRP A 1 709 ? -38.889 9.839 25.917 1.00 24.36 ? 729 TRP A CG 1 ATOM 5622 C CD1 . TRP A 1 709 ? -39.879 9.928 24.987 1.00 24.18 ? 729 TRP A CD1 1 ATOM 5623 C CD2 . TRP A 1 709 ? -37.772 9.232 25.259 1.00 22.31 ? 729 TRP A CD2 1 ATOM 5624 N NE1 . TRP A 1 709 ? -39.456 9.406 23.798 1.00 23.99 ? 729 TRP A NE1 1 ATOM 5625 C CE2 . TRP A 1 709 ? -38.158 8.985 23.930 1.00 23.10 ? 729 TRP A CE2 1 ATOM 5626 C CE3 . TRP A 1 709 ? -36.483 8.870 25.667 1.00 21.48 ? 729 TRP A CE3 1 ATOM 5627 C CZ2 . TRP A 1 709 ? -37.306 8.376 23.002 1.00 22.27 ? 729 TRP A CZ2 1 ATOM 5628 C CZ3 . TRP A 1 709 ? -35.629 8.278 24.742 1.00 21.55 ? 729 TRP A CZ3 1 ATOM 5629 C CH2 . TRP A 1 709 ? -36.045 8.032 23.432 1.00 21.62 ? 729 TRP A CH2 1 ATOM 5630 N N . ILE A 1 710 ? -37.557 12.647 29.605 1.00 26.99 ? 730 ILE A N 1 ATOM 5631 C CA . ILE A 1 710 ? -37.655 13.406 30.842 1.00 28.04 ? 730 ILE A CA 1 ATOM 5632 C C . ILE A 1 710 ? -36.528 14.441 30.777 1.00 28.70 ? 730 ILE A C 1 ATOM 5633 O O . ILE A 1 710 ? -35.409 14.098 30.389 1.00 28.97 ? 730 ILE A O 1 ATOM 5634 C CB . ILE A 1 710 ? -37.456 12.518 32.096 1.00 28.10 ? 730 ILE A CB 1 ATOM 5635 C CG1 . ILE A 1 710 ? -38.697 11.665 32.368 1.00 28.00 ? 730 ILE A CG1 1 ATOM 5636 C CG2 . ILE A 1 710 ? -37.175 13.377 33.323 1.00 28.65 ? 730 ILE A CG2 1 ATOM 5637 C CD1 . ILE A 1 710 ? -38.503 10.654 33.493 1.00 29.60 ? 730 ILE A CD1 1 ATOM 5638 N N . PRO A 1 711 ? -36.808 15.702 31.144 1.00 29.45 ? 731 PRO A N 1 ATOM 5639 C CA . PRO A 1 711 ? -35.738 16.696 31.031 1.00 29.93 ? 731 PRO A CA 1 ATOM 5640 C C . PRO A 1 711 ? -34.545 16.367 31.921 1.00 30.19 ? 731 PRO A C 1 ATOM 5641 O O . PRO A 1 711 ? -34.699 15.721 32.959 1.00 29.62 ? 731 PRO A O 1 ATOM 5642 C CB . PRO A 1 711 ? -36.408 18.007 31.473 1.00 29.77 ? 731 PRO A CB 1 ATOM 5643 C CG . PRO A 1 711 ? -37.664 17.603 32.162 1.00 29.97 ? 731 PRO A CG 1 ATOM 5644 C CD . PRO A 1 711 ? -38.081 16.305 31.571 1.00 29.53 ? 731 PRO A CD 1 ATOM 5645 N N . GLU A 1 712 ? -33.367 16.795 31.491 1.00 31.14 ? 732 GLU A N 1 ATOM 5646 C CA . GLU A 1 712 ? -32.159 16.638 32.285 1.00 32.10 ? 732 GLU A CA 1 ATOM 5647 C C . GLU A 1 712 ? -32.336 17.334 33.629 1.00 33.61 ? 732 GLU A C 1 ATOM 5648 O O . GLU A 1 712 ? -32.843 18.451 33.695 1.00 33.63 ? 732 GLU A O 1 ATOM 5649 C CB . GLU A 1 712 ? -30.954 17.224 31.545 1.00 31.75 ? 732 GLU A CB 1 ATOM 5650 C CG . GLU A 1 712 ? -29.625 16.988 32.253 1.00 30.93 ? 732 GLU A CG 1 ATOM 5651 C CD . GLU A 1 712 ? -28.431 17.557 31.507 1.00 29.39 ? 732 GLU A CD 1 ATOM 5652 O OE1 . GLU A 1 712 ? -28.609 18.133 30.417 1.00 28.83 ? 732 GLU A OE1 1 ATOM 5653 O OE2 . GLU A 1 712 ? -27.300 17.413 32.008 1.00 28.82 ? 732 GLU A OE2 1 ATOM 5654 N N . ASP A 1 713 ? -31.928 16.663 34.701 1.00 35.55 ? 733 ASP A N 1 ATOM 5655 C CA . ASP A 1 713 ? -32.019 17.237 36.041 1.00 37.02 ? 733 ASP A CA 1 ATOM 5656 C C . ASP A 1 713 ? -30.659 17.632 36.586 1.00 37.62 ? 733 ASP A C 1 ATOM 5657 O O . ASP A 1 713 ? -29.735 16.829 36.597 1.00 38.07 ? 733 ASP A O 1 ATOM 5658 C CB . ASP A 1 713 ? -32.633 16.238 37.013 1.00 37.22 ? 733 ASP A CB 1 ATOM 5659 C CG . ASP A 1 713 ? -32.349 16.597 38.470 1.00 38.46 ? 733 ASP A CG 1 ATOM 5660 O OD1 . ASP A 1 713 ? -32.759 17.712 38.870 1.00 38.25 ? 733 ASP A OD1 1 ATOM 5661 O OD2 . ASP A 1 713 ? -31.718 15.777 39.199 1.00 37.77 ? 733 ASP A OD2 1 ATOM 5662 N N . ARG A 1 714 ? -30.541 18.864 37.060 1.00 38.52 ? 734 ARG A N 1 ATOM 5663 C CA . ARG A 1 714 ? -29.387 19.235 37.886 1.00 39.30 ? 734 ARG A CA 1 ATOM 5664 C C . ARG A 1 714 ? -29.811 19.943 39.183 1.00 39.27 ? 734 ARG A C 1 ATOM 5665 O O . ARG A 1 714 ? -28.958 20.488 39.902 1.00 39.74 ? 734 ARG A O 1 ATOM 5666 C CB . ARG A 1 714 ? -28.403 20.084 37.075 1.00 39.54 ? 734 ARG A CB 1 ATOM 5667 C CG . ARG A 1 714 ? -27.973 19.424 35.757 1.00 41.03 ? 734 ARG A CG 1 ATOM 5668 C CD . ARG A 1 714 ? -27.342 20.427 34.823 1.00 42.99 ? 734 ARG A CD 1 ATOM 5669 N NE . ARG A 1 714 ? -26.025 20.820 35.314 1.00 44.27 ? 734 ARG A NE 1 ATOM 5670 C CZ . ARG A 1 714 ? -25.452 21.999 35.096 1.00 45.78 ? 734 ARG A CZ 1 ATOM 5671 N NH1 . ARG A 1 714 ? -26.071 22.946 34.390 1.00 46.75 ? 734 ARG A NH1 1 ATOM 5672 N NH2 . ARG A 1 714 ? -24.244 22.236 35.595 1.00 46.55 ? 734 ARG A NH2 1 ATOM 5673 N N . ASP A 1 715 ? -31.109 19.892 39.501 1.00 38.72 ? 735 ASP A N 1 ATOM 5674 C CA . ASP A 1 715 ? -31.651 20.549 40.694 1.00 38.40 ? 735 ASP A CA 1 ATOM 5675 C C . ASP A 1 715 ? -30.950 20.132 41.969 1.00 37.83 ? 735 ASP A C 1 ATOM 5676 O O . ASP A 1 715 ? -30.323 19.079 42.039 1.00 37.86 ? 735 ASP A O 1 ATOM 5677 C CB . ASP A 1 715 ? -33.143 20.248 40.860 1.00 38.48 ? 735 ASP A CB 1 ATOM 5678 C CG . ASP A 1 715 ? -34.003 21.000 39.882 1.00 39.13 ? 735 ASP A CG 1 ATOM 5679 O OD1 . ASP A 1 715 ? -33.456 21.528 38.893 1.00 40.52 ? 735 ASP A OD1 1 ATOM 5680 O OD2 . ASP A 1 715 ? -35.231 21.072 40.112 1.00 40.53 ? 735 ASP A OD2 1 ATOM 5681 N N . CYS A 1 716 ? -31.094 20.969 42.986 1.00 37.47 ? 736 CYS A N 1 ATOM 5682 C CA . CYS A 1 716 ? -30.512 20.723 44.288 1.00 37.20 ? 736 CYS A CA 1 ATOM 5683 C C . CYS A 1 716 ? -31.545 20.840 45.397 1.00 36.61 ? 736 CYS A C 1 ATOM 5684 O O . CYS A 1 716 ? -32.540 21.555 45.285 1.00 36.50 ? 736 CYS A O 1 ATOM 5685 C CB . CYS A 1 716 ? -29.346 21.686 44.538 1.00 37.34 ? 736 CYS A CB 1 ATOM 5686 S SG . CYS A 1 716 ? -27.730 20.935 44.208 1.00 38.62 ? 736 CYS A SG 1 ATOM 5687 N N . SER A 1 717 ? -31.301 20.095 46.461 1.00 36.29 ? 737 SER A N 1 ATOM 5688 C CA . SER A 1 717 ? -32.118 20.154 47.660 1.00 35.89 ? 737 SER A CA 1 ATOM 5689 C C . SER A 1 717 ? -31.219 19.754 48.803 1.00 35.90 ? 737 SER A C 1 ATOM 5690 O O . SER A 1 717 ? -30.091 19.329 48.577 1.00 35.11 ? 737 SER A O 1 ATOM 5691 C CB . SER A 1 717 ? -33.306 19.197 47.559 1.00 36.00 ? 737 SER A CB 1 ATOM 5692 O OG . SER A 1 717 ? -32.870 17.873 47.295 1.00 34.43 ? 737 SER A OG 1 ATOM 5693 N N . MET A 1 718 ? -31.720 19.895 50.022 1.00 36.11 ? 738 MET A N 1 ATOM 5694 C CA . MET A 1 718 ? -30.972 19.514 51.208 1.00 36.68 ? 738 MET A CA 1 ATOM 5695 C C . MET A 1 718 ? -31.838 18.648 52.094 1.00 36.06 ? 738 MET A C 1 ATOM 5696 O O . MET A 1 718 ? -33.048 18.894 52.216 1.00 35.89 ? 738 MET A O 1 ATOM 5697 C CB . MET A 1 718 ? -30.556 20.733 52.012 1.00 37.29 ? 738 MET A CB 1 ATOM 5698 C CG . MET A 1 718 ? -29.721 21.736 51.257 1.00 39.92 ? 738 MET A CG 1 ATOM 5699 S SD . MET A 1 718 ? -29.242 23.078 52.369 1.00 46.90 ? 738 MET A SD 1 ATOM 5700 C CE . MET A 1 718 ? -30.857 23.615 52.972 1.00 44.74 ? 738 MET A CE 1 ATOM 5701 N N . PRO A 1 719 ? -31.220 17.643 52.730 1.00 35.26 ? 739 PRO A N 1 ATOM 5702 C CA . PRO A 1 719 ? -31.920 16.810 53.687 1.00 34.87 ? 739 PRO A CA 1 ATOM 5703 C C . PRO A 1 719 ? -32.049 17.514 55.027 1.00 34.38 ? 739 PRO A C 1 ATOM 5704 O O . PRO A 1 719 ? -31.270 18.433 55.319 1.00 33.88 ? 739 PRO A O 1 ATOM 5705 C CB . PRO A 1 719 ? -30.982 15.616 53.835 1.00 35.18 ? 739 PRO A CB 1 ATOM 5706 C CG . PRO A 1 719 ? -29.630 16.214 53.683 1.00 34.81 ? 739 PRO A CG 1 ATOM 5707 C CD . PRO A 1 719 ? -29.797 17.266 52.622 1.00 35.21 ? 739 PRO A CD 1 ATOM 5708 N N . PRO A 1 720 ? -32.998 17.063 55.866 1.00 33.93 ? 740 PRO A N 1 ATOM 5709 C CA . PRO A 1 720 ? -33.066 17.675 57.191 1.00 33.60 ? 740 PRO A CA 1 ATOM 5710 C C . PRO A 1 720 ? -31.801 17.356 57.969 1.00 32.95 ? 740 PRO A C 1 ATOM 5711 O O . PRO A 1 720 ? -31.127 16.379 57.649 1.00 32.54 ? 740 PRO A O 1 ATOM 5712 C CB . PRO A 1 720 ? -34.281 17.009 57.850 1.00 33.84 ? 740 PRO A CB 1 ATOM 5713 C CG . PRO A 1 720 ? -34.854 16.059 56.833 1.00 33.99 ? 740 PRO A CG 1 ATOM 5714 C CD . PRO A 1 720 ? -33.879 15.893 55.729 1.00 33.85 ? 740 PRO A CD 1 ATOM 5715 N N . PRO A 1 721 ? -31.465 18.185 58.972 1.00 32.25 ? 741 PRO A N 1 ATOM 5716 C CA . PRO A 1 721 ? -30.334 17.856 59.818 1.00 31.62 ? 741 PRO A CA 1 ATOM 5717 C C . PRO A 1 721 ? -30.511 16.475 60.436 1.00 30.94 ? 741 PRO A C 1 ATOM 5718 O O . PRO A 1 721 ? -31.642 16.036 60.681 1.00 30.71 ? 741 PRO A O 1 ATOM 5719 C CB . PRO A 1 721 ? -30.372 18.940 60.912 1.00 31.87 ? 741 PRO A CB 1 ATOM 5720 C CG . PRO A 1 721 ? -31.106 20.065 60.312 1.00 32.34 ? 741 PRO A CG 1 ATOM 5721 C CD . PRO A 1 721 ? -32.079 19.476 59.337 1.00 32.29 ? 741 PRO A CD 1 ATOM 5722 N N . PHE A 1 722 ? -29.393 15.804 60.668 1.00 30.02 ? 742 PHE A N 1 ATOM 5723 C CA . PHE A 1 722 ? -29.384 14.517 61.323 1.00 29.55 ? 742 PHE A CA 1 ATOM 5724 C C . PHE A 1 722 ? -29.959 14.630 62.725 1.00 29.49 ? 742 PHE A C 1 ATOM 5725 O O . PHE A 1 722 ? -29.612 15.550 63.462 1.00 29.97 ? 742 PHE A O 1 ATOM 5726 C CB . PHE A 1 722 ? -27.954 13.999 61.414 1.00 29.42 ? 742 PHE A CB 1 ATOM 5727 C CG . PHE A 1 722 ? -27.833 12.693 62.139 1.00 28.76 ? 742 PHE A CG 1 ATOM 5728 C CD1 . PHE A 1 722 ? -27.900 11.496 61.447 1.00 27.93 ? 742 PHE A CD1 1 ATOM 5729 C CD2 . PHE A 1 722 ? -27.661 12.660 63.511 1.00 28.66 ? 742 PHE A CD2 1 ATOM 5730 C CE1 . PHE A 1 722 ? -27.790 10.280 62.106 1.00 27.73 ? 742 PHE A CE1 1 ATOM 5731 C CE2 . PHE A 1 722 ? -27.556 11.456 64.181 1.00 29.14 ? 742 PHE A CE2 1 ATOM 5732 C CZ . PHE A 1 722 ? -27.621 10.261 63.482 1.00 28.66 ? 742 PHE A CZ 1 ATOM 5733 N N . SER A 1 723 ? -30.843 13.702 63.079 1.00 28.88 ? 743 SER A N 1 ATOM 5734 C CA . SER A 1 723 ? -31.241 13.498 64.467 1.00 28.71 ? 743 SER A CA 1 ATOM 5735 C C . SER A 1 723 ? -31.282 12.001 64.763 1.00 28.35 ? 743 SER A C 1 ATOM 5736 O O . SER A 1 723 ? -31.334 11.168 63.851 1.00 28.36 ? 743 SER A O 1 ATOM 5737 C CB . SER A 1 723 ? -32.600 14.151 64.776 1.00 28.84 ? 743 SER A CB 1 ATOM 5738 O OG . SER A 1 723 ? -33.641 13.599 63.985 1.00 29.65 ? 743 SER A OG 1 ATOM 5739 N N . TYR A 1 724 ? -31.226 11.669 66.046 1.00 27.79 ? 744 TYR A N 1 ATOM 5740 C CA . TYR A 1 724 ? -31.337 10.288 66.500 1.00 27.29 ? 744 TYR A CA 1 ATOM 5741 C C . TYR A 1 724 ? -31.849 10.258 67.936 1.00 26.98 ? 744 TYR A C 1 ATOM 5742 O O . TYR A 1 724 ? -31.330 10.969 68.788 1.00 26.59 ? 744 TYR A O 1 ATOM 5743 C CB . TYR A 1 724 ? -29.983 9.593 66.426 1.00 26.86 ? 744 TYR A CB 1 ATOM 5744 C CG . TYR A 1 724 ? -30.111 8.102 66.475 1.00 26.88 ? 744 TYR A CG 1 ATOM 5745 C CD1 . TYR A 1 724 ? -30.411 7.381 65.322 1.00 27.12 ? 744 TYR A CD1 1 ATOM 5746 C CD2 . TYR A 1 724 ? -29.963 7.406 67.668 1.00 25.42 ? 744 TYR A CD2 1 ATOM 5747 C CE1 . TYR A 1 724 ? -30.541 6.007 65.350 1.00 26.58 ? 744 TYR A CE1 1 ATOM 5748 C CE2 . TYR A 1 724 ? -30.088 6.030 67.706 1.00 25.04 ? 744 TYR A CE2 1 ATOM 5749 C CZ . TYR A 1 724 ? -30.380 5.338 66.543 1.00 25.70 ? 744 TYR A CZ 1 ATOM 5750 O OH . TYR A 1 724 ? -30.517 3.981 66.560 1.00 24.98 ? 744 TYR A OH 1 ATOM 5751 N N . ASN A 1 725 ? -32.855 9.428 68.197 1.00 26.46 ? 745 ASN A N 1 ATOM 5752 C CA . ASN A 1 725 ? -33.510 9.395 69.494 1.00 26.13 ? 745 ASN A CA 1 ATOM 5753 C C . ASN A 1 725 ? -32.986 8.328 70.451 1.00 25.87 ? 745 ASN A C 1 ATOM 5754 O O . ASN A 1 725 ? -32.578 8.641 71.571 1.00 25.88 ? 745 ASN A O 1 ATOM 5755 C CB . ASN A 1 725 ? -35.011 9.218 69.319 1.00 26.45 ? 745 ASN A CB 1 ATOM 5756 C CG . ASN A 1 725 ? -35.758 9.469 70.594 1.00 27.07 ? 745 ASN A CG 1 ATOM 5757 O OD1 . ASN A 1 725 ? -35.911 8.586 71.425 1.00 27.86 ? 745 ASN A OD1 1 ATOM 5758 N ND2 . ASN A 1 725 ? -36.211 10.694 70.765 1.00 30.88 ? 745 ASN A ND2 1 ATOM 5759 N N . GLY A 1 726 ? -33.028 7.069 70.027 1.00 25.43 ? 746 GLY A N 1 ATOM 5760 C CA . GLY A 1 726 ? -32.494 5.959 70.817 1.00 24.72 ? 746 GLY A CA 1 ATOM 5761 C C . GLY A 1 726 ? -33.436 5.355 71.848 1.00 24.43 ? 746 GLY A C 1 ATOM 5762 O O . GLY A 1 726 ? -33.103 4.338 72.464 1.00 24.16 ? 746 GLY A O 1 ATOM 5763 N N . THR A 1 727 ? -34.596 5.971 72.057 1.00 24.12 ? 747 THR A N 1 ATOM 5764 C CA . THR A 1 727 ? -35.595 5.430 72.978 1.00 23.74 ? 747 THR A CA 1 ATOM 5765 C C . THR A 1 727 ? -36.792 4.880 72.223 1.00 23.71 ? 747 THR A C 1 ATOM 5766 O O . THR A 1 727 ? -37.074 5.268 71.085 1.00 23.62 ? 747 THR A O 1 ATOM 5767 C CB . THR A 1 727 ? -36.084 6.465 74.023 1.00 23.68 ? 747 THR A CB 1 ATOM 5768 O OG1 . THR A 1 727 ? -37.006 7.373 73.425 1.00 22.89 ? 747 THR A OG1 1 ATOM 5769 C CG2 . THR A 1 727 ? -34.910 7.236 74.629 1.00 23.60 ? 747 THR A CG2 1 ATOM 5770 N N . TYR A 1 728 ? -37.471 3.946 72.875 1.00 24.03 ? 748 TYR A N 1 ATOM 5771 C CA . TYR A 1 728 ? -38.617 3.256 72.318 1.00 24.27 ? 748 TYR A CA 1 ATOM 5772 C C . TYR A 1 728 ? -39.557 3.008 73.488 1.00 24.76 ? 748 TYR A C 1 ATOM 5773 O O . TYR A 1 728 ? -39.215 2.277 74.421 1.00 24.44 ? 748 TYR A O 1 ATOM 5774 C CB . TYR A 1 728 ? -38.200 1.942 71.613 1.00 24.05 ? 748 TYR A CB 1 ATOM 5775 C CG . TYR A 1 728 ? -37.146 1.139 72.355 1.00 24.06 ? 748 TYR A CG 1 ATOM 5776 C CD1 . TYR A 1 728 ? -37.485 -0.002 73.085 1.00 23.89 ? 748 TYR A CD1 1 ATOM 5777 C CD2 . TYR A 1 728 ? -35.808 1.539 72.352 1.00 24.24 ? 748 TYR A CD2 1 ATOM 5778 C CE1 . TYR A 1 728 ? -36.510 -0.727 73.778 1.00 24.00 ? 748 TYR A CE1 1 ATOM 5779 C CE2 . TYR A 1 728 ? -34.842 0.829 73.045 1.00 22.46 ? 748 TYR A CE2 1 ATOM 5780 C CZ . TYR A 1 728 ? -35.195 -0.291 73.757 1.00 23.83 ? 748 TYR A CZ 1 ATOM 5781 O OH . TYR A 1 728 ? -34.221 -0.986 74.441 1.00 25.40 ? 748 TYR A OH 1 ATOM 5782 N N . ARG A 1 729 ? -40.714 3.664 73.461 1.00 25.32 ? 749 ARG A N 1 ATOM 5783 C CA . ARG A 1 729 ? -41.596 3.706 74.624 1.00 26.23 ? 749 ARG A CA 1 ATOM 5784 C C . ARG A 1 729 ? -43.056 3.708 74.202 1.00 26.07 ? 749 ARG A C 1 ATOM 5785 O O . ARG A 1 729 ? -43.370 4.060 73.075 1.00 25.44 ? 749 ARG A O 1 ATOM 5786 C CB . ARG A 1 729 ? -41.336 4.982 75.450 1.00 26.76 ? 749 ARG A CB 1 ATOM 5787 C CG . ARG A 1 729 ? -39.884 5.289 75.780 1.00 28.47 ? 749 ARG A CG 1 ATOM 5788 C CD . ARG A 1 729 ? -39.398 4.478 76.948 1.00 31.29 ? 749 ARG A CD 1 ATOM 5789 N NE . ARG A 1 729 ? -37.943 4.516 77.099 1.00 33.10 ? 749 ARG A NE 1 ATOM 5790 C CZ . ARG A 1 729 ? -37.244 5.565 77.534 1.00 35.43 ? 749 ARG A CZ 1 ATOM 5791 N NH1 . ARG A 1 729 ? -37.843 6.716 77.840 1.00 36.69 ? 749 ARG A NH1 1 ATOM 5792 N NH2 . ARG A 1 729 ? -35.920 5.469 77.648 1.00 36.10 ? 749 ARG A NH2 1 ATOM 5793 N N . PRO A 1 730 ? -43.965 3.373 75.127 1.00 27.04 ? 750 PRO A N 1 ATOM 5794 C CA . PRO A 1 730 ? -45.401 3.505 74.829 1.00 27.58 ? 750 PRO A CA 1 ATOM 5795 C C . PRO A 1 730 ? -45.835 4.935 74.512 1.00 28.22 ? 750 PRO A C 1 ATOM 5796 O O . PRO A 1 730 ? -45.216 5.887 74.955 1.00 28.24 ? 750 PRO A O 1 ATOM 5797 C CB . PRO A 1 730 ? -46.081 3.023 76.120 1.00 27.58 ? 750 PRO A CB 1 ATOM 5798 C CG . PRO A 1 730 ? -45.046 2.216 76.833 1.00 27.35 ? 750 PRO A CG 1 ATOM 5799 C CD . PRO A 1 730 ? -43.731 2.841 76.481 1.00 26.94 ? 750 PRO A CD 1 ATOM 5800 N N . VAL A 1 731 ? -46.893 5.074 73.729 1.00 29.25 ? 751 VAL A N 1 ATOM 5801 C CA . VAL A 1 731 ? -47.473 6.375 73.448 1.00 29.79 ? 751 VAL A CA 1 ATOM 5802 C C . VAL A 1 731 ? -48.959 6.294 73.752 1.00 30.43 ? 751 VAL A C 1 ATOM 5803 O O . VAL A 1 731 ? -49.643 5.312 73.433 1.00 30.36 ? 751 VAL A O 1 ATOM 5804 C CB . VAL A 1 731 ? -47.238 6.798 71.988 1.00 30.24 ? 751 VAL A CB 1 ATOM 5805 C CG1 . VAL A 1 731 ? -48.167 7.947 71.591 1.00 29.96 ? 751 VAL A CG1 1 ATOM 5806 C CG2 . VAL A 1 731 ? -45.761 7.181 71.779 1.00 29.81 ? 751 VAL A CG2 1 ATOM 5807 O OXT . VAL A 1 731 ? -49.493 7.219 74.357 1.00 31.42 ? 751 VAL A OXT 1 ATOM 5808 N N . ARG B 1 8 ? 5.631 9.670 39.989 1.00 45.11 ? 28 ARG B N 1 ATOM 5809 C CA . ARG B 1 8 ? 5.020 8.384 40.420 1.00 44.83 ? 28 ARG B CA 1 ATOM 5810 C C . ARG B 1 8 ? 5.801 7.204 39.845 1.00 44.60 ? 28 ARG B C 1 ATOM 5811 O O . ARG B 1 8 ? 6.152 7.201 38.659 1.00 45.12 ? 28 ARG B O 1 ATOM 5812 C CB . ARG B 1 8 ? 3.552 8.309 39.972 1.00 44.83 ? 28 ARG B CB 1 ATOM 5813 N N . LYS B 1 9 ? 6.067 6.212 40.693 1.00 43.84 ? 29 LYS B N 1 ATOM 5814 C CA . LYS B 1 9 ? 6.653 4.942 40.262 1.00 43.18 ? 29 LYS B CA 1 ATOM 5815 C C . LYS B 1 9 ? 5.659 4.081 39.470 1.00 42.23 ? 29 LYS B C 1 ATOM 5816 O O . LYS B 1 9 ? 6.069 3.268 38.638 1.00 42.19 ? 29 LYS B O 1 ATOM 5817 C CB . LYS B 1 9 ? 7.167 4.158 41.472 1.00 43.44 ? 29 LYS B CB 1 ATOM 5818 C CG . LYS B 1 9 ? 8.331 4.842 42.203 1.00 44.36 ? 29 LYS B CG 1 ATOM 5819 C CD . LYS B 1 9 ? 8.902 3.949 43.304 1.00 45.01 ? 29 LYS B CD 1 ATOM 5820 C CE . LYS B 1 9 ? 10.308 4.378 43.713 1.00 45.21 ? 29 LYS B CE 1 ATOM 5821 N NZ . LYS B 1 9 ? 11.081 3.224 44.258 1.00 45.75 ? 29 LYS B NZ 1 ATOM 5822 N N . ALA B 1 10 ? 4.360 4.280 39.727 1.00 40.80 ? 30 ALA B N 1 ATOM 5823 C CA . ALA B 1 10 ? 3.272 3.604 38.996 1.00 39.50 ? 30 ALA B CA 1 ATOM 5824 C C . ALA B 1 10 ? 3.327 3.783 37.466 1.00 38.24 ? 30 ALA B C 1 ATOM 5825 O O . ALA B 1 10 ? 2.692 3.025 36.725 1.00 38.28 ? 30 ALA B O 1 ATOM 5826 C CB . ALA B 1 10 ? 1.916 4.080 39.525 1.00 39.32 ? 30 ALA B CB 1 ATOM 5827 N N . GLY B 1 11 ? 4.058 4.798 37.009 1.00 36.51 ? 31 GLY B N 1 ATOM 5828 C CA . GLY B 1 11 ? 4.364 4.986 35.591 1.00 35.25 ? 31 GLY B CA 1 ATOM 5829 C C . GLY B 1 11 ? 4.957 3.769 34.897 1.00 34.01 ? 31 GLY B C 1 ATOM 5830 O O . GLY B 1 11 ? 4.742 3.582 33.706 1.00 33.45 ? 31 GLY B O 1 ATOM 5831 N N . VAL B 1 12 ? 5.694 2.936 35.634 1.00 32.74 ? 32 VAL B N 1 ATOM 5832 C CA . VAL B 1 12 ? 6.195 1.665 35.089 1.00 31.87 ? 32 VAL B CA 1 ATOM 5833 C C . VAL B 1 12 ? 5.054 0.779 34.544 1.00 31.33 ? 32 VAL B C 1 ATOM 5834 O O . VAL B 1 12 ? 5.253 0.017 33.591 1.00 30.69 ? 32 VAL B O 1 ATOM 5835 C CB . VAL B 1 12 ? 7.041 0.873 36.126 1.00 31.68 ? 32 VAL B CB 1 ATOM 5836 C CG1 . VAL B 1 12 ? 6.184 0.426 37.304 1.00 31.68 ? 32 VAL B CG1 1 ATOM 5837 C CG2 . VAL B 1 12 ? 7.703 -0.334 35.471 1.00 30.94 ? 32 VAL B CG2 1 ATOM 5838 N N . PHE B 1 13 ? 3.870 0.900 35.150 1.00 30.81 ? 33 PHE B N 1 ATOM 5839 C CA . PHE B 1 13 ? 2.679 0.154 34.744 1.00 30.56 ? 33 PHE B CA 1 ATOM 5840 C C . PHE B 1 13 ? 1.784 0.901 33.723 1.00 30.65 ? 33 PHE B C 1 ATOM 5841 O O . PHE B 1 13 ? 0.744 0.378 33.320 1.00 30.73 ? 33 PHE B O 1 ATOM 5842 C CB . PHE B 1 13 ? 1.812 -0.175 35.984 1.00 30.38 ? 33 PHE B CB 1 ATOM 5843 C CG . PHE B 1 13 ? 2.523 -0.977 37.041 1.00 29.03 ? 33 PHE B CG 1 ATOM 5844 C CD1 . PHE B 1 13 ? 2.935 -2.276 36.787 1.00 28.84 ? 33 PHE B CD1 1 ATOM 5845 C CD2 . PHE B 1 13 ? 2.750 -0.446 38.299 1.00 28.35 ? 33 PHE B CD2 1 ATOM 5846 C CE1 . PHE B 1 13 ? 3.575 -3.019 37.762 1.00 27.21 ? 33 PHE B CE1 1 ATOM 5847 C CE2 . PHE B 1 13 ? 3.396 -1.190 39.277 1.00 27.56 ? 33 PHE B CE2 1 ATOM 5848 C CZ . PHE B 1 13 ? 3.805 -2.474 39.005 1.00 26.84 ? 33 PHE B CZ 1 ATOM 5849 N N . SER B 1 14 ? 2.158 2.109 33.318 1.00 30.48 ? 34 SER B N 1 ATOM 5850 C CA . SER B 1 14 ? 1.249 2.940 32.526 1.00 30.65 ? 34 SER B CA 1 ATOM 5851 C C . SER B 1 14 ? 1.232 2.555 31.045 1.00 30.44 ? 34 SER B C 1 ATOM 5852 O O . SER B 1 14 ? 2.239 2.108 30.482 1.00 30.30 ? 34 SER B O 1 ATOM 5853 C CB . SER B 1 14 ? 1.599 4.417 32.678 1.00 30.70 ? 34 SER B CB 1 ATOM 5854 O OG . SER B 1 14 ? 2.923 4.672 32.244 1.00 32.39 ? 34 SER B OG 1 ATOM 5855 N N . ASP B 1 15 ? 0.069 2.731 30.424 1.00 30.15 ? 35 ASP B N 1 ATOM 5856 C CA . ASP B 1 15 ? -0.097 2.473 29.004 1.00 29.81 ? 35 ASP B CA 1 ATOM 5857 C C . ASP B 1 15 ? 0.677 3.519 28.210 1.00 29.41 ? 35 ASP B C 1 ATOM 5858 O O . ASP B 1 15 ? 1.060 4.557 28.738 1.00 29.20 ? 35 ASP B O 1 ATOM 5859 C CB . ASP B 1 15 ? -1.576 2.521 28.605 1.00 30.03 ? 35 ASP B CB 1 ATOM 5860 C CG . ASP B 1 15 ? -2.382 1.397 29.207 1.00 30.84 ? 35 ASP B CG 1 ATOM 5861 O OD1 . ASP B 1 15 ? -2.040 0.209 28.972 1.00 34.25 ? 35 ASP B OD1 1 ATOM 5862 O OD2 . ASP B 1 15 ? -3.369 1.695 29.910 1.00 29.89 ? 35 ASP B OD2 1 ATOM 5863 N N . LEU B 1 16 ? 0.906 3.237 26.934 1.00 29.20 ? 36 LEU B N 1 ATOM 5864 C CA . LEU B 1 16 ? 1.632 4.161 26.080 1.00 28.93 ? 36 LEU B CA 1 ATOM 5865 C C . LEU B 1 16 ? 0.784 5.388 25.819 1.00 28.71 ? 36 LEU B C 1 ATOM 5866 O O . LEU B 1 16 ? -0.426 5.284 25.590 1.00 29.03 ? 36 LEU B O 1 ATOM 5867 C CB . LEU B 1 16 ? 2.004 3.504 24.749 1.00 28.89 ? 36 LEU B CB 1 ATOM 5868 C CG . LEU B 1 16 ? 2.863 2.241 24.818 1.00 28.85 ? 36 LEU B CG 1 ATOM 5869 C CD1 . LEU B 1 16 ? 3.201 1.769 23.402 1.00 27.98 ? 36 LEU B CD1 1 ATOM 5870 C CD2 . LEU B 1 16 ? 4.133 2.467 25.652 1.00 28.29 ? 36 LEU B CD2 1 ATOM 5871 N N . SER B 1 17 ? 1.418 6.554 25.870 1.00 28.27 ? 37 SER B N 1 ATOM 5872 C CA . SER B 1 17 ? 0.766 7.795 25.476 1.00 28.06 ? 37 SER B CA 1 ATOM 5873 C C . SER B 1 17 ? 0.619 7.855 23.953 1.00 27.54 ? 37 SER B C 1 ATOM 5874 O O . SER B 1 17 ? 1.131 6.998 23.228 1.00 27.01 ? 37 SER B O 1 ATOM 5875 C CB . SER B 1 17 ? 1.571 8.999 25.965 1.00 28.19 ? 37 SER B CB 1 ATOM 5876 O OG . SER B 1 17 ? 2.826 9.046 25.320 1.00 28.30 ? 37 SER B OG 1 ATOM 5877 N N . ASN B 1 18 ? -0.113 8.859 23.490 1.00 27.16 ? 38 ASN B N 1 ATOM 5878 C CA . ASN B 1 18 ? -0.213 9.168 22.072 1.00 27.19 ? 38 ASN B CA 1 ATOM 5879 C C . ASN B 1 18 ? 1.187 9.354 21.486 1.00 27.19 ? 38 ASN B C 1 ATOM 5880 O O . ASN B 1 18 ? 1.511 8.796 20.439 1.00 27.08 ? 38 ASN B O 1 ATOM 5881 C CB . ASN B 1 18 ? -1.033 10.448 21.895 1.00 27.25 ? 38 ASN B CB 1 ATOM 5882 C CG . ASN B 1 18 ? -1.541 10.652 20.477 1.00 26.73 ? 38 ASN B CG 1 ATOM 5883 O OD1 . ASN B 1 18 ? -1.645 9.720 19.687 1.00 25.66 ? 38 ASN B OD1 1 ATOM 5884 N ND2 . ASN B 1 18 ? -1.896 11.892 20.166 1.00 26.74 ? 38 ASN B ND2 1 ATOM 5885 N N . GLN B 1 19 ? 2.014 10.115 22.194 1.00 27.42 ? 39 GLN B N 1 ATOM 5886 C CA . GLN B 1 19 ? 3.385 10.393 21.776 1.00 27.54 ? 39 GLN B CA 1 ATOM 5887 C C . GLN B 1 19 ? 4.185 9.111 21.618 1.00 27.80 ? 39 GLN B C 1 ATOM 5888 O O . GLN B 1 19 ? 4.848 8.907 20.606 1.00 27.85 ? 39 GLN B O 1 ATOM 5889 C CB . GLN B 1 19 ? 4.073 11.318 22.787 1.00 27.55 ? 39 GLN B CB 1 ATOM 5890 N N . GLU B 1 20 ? 4.109 8.239 22.617 1.00 27.93 ? 40 GLU B N 1 ATOM 5891 C CA . GLU B 1 20 ? 4.813 6.970 22.568 1.00 28.00 ? 40 GLU B CA 1 ATOM 5892 C C . GLU B 1 20 ? 4.327 6.057 21.439 1.00 28.07 ? 40 GLU B C 1 ATOM 5893 O O . GLU B 1 20 ? 5.141 5.415 20.758 1.00 27.81 ? 40 GLU B O 1 ATOM 5894 C CB . GLU B 1 20 ? 4.710 6.271 23.917 1.00 28.47 ? 40 GLU B CB 1 ATOM 5895 C CG . GLU B 1 20 ? 5.519 6.964 25.011 1.00 28.98 ? 40 GLU B CG 1 ATOM 5896 C CD . GLU B 1 20 ? 5.368 6.286 26.360 1.00 29.86 ? 40 GLU B CD 1 ATOM 5897 O OE1 . GLU B 1 20 ? 4.212 6.093 26.806 1.00 28.82 ? 40 GLU B OE1 1 ATOM 5898 O OE2 . GLU B 1 20 ? 6.402 5.949 26.976 1.00 28.98 ? 40 GLU B OE2 1 ATOM 5899 N N . LEU B 1 21 ? 3.014 6.021 21.219 1.00 27.62 ? 41 LEU B N 1 ATOM 5900 C CA . LEU B 1 21 ? 2.451 5.209 20.145 1.00 27.47 ? 41 LEU B CA 1 ATOM 5901 C C . LEU B 1 21 ? 2.962 5.658 18.773 1.00 27.64 ? 41 LEU B C 1 ATOM 5902 O O . LEU B 1 21 ? 3.377 4.833 17.960 1.00 26.83 ? 41 LEU B O 1 ATOM 5903 C CB . LEU B 1 21 ? 0.914 5.215 20.193 1.00 27.22 ? 41 LEU B CB 1 ATOM 5904 C CG . LEU B 1 21 ? 0.296 4.378 21.328 1.00 26.32 ? 41 LEU B CG 1 ATOM 5905 C CD1 . LEU B 1 21 ? -1.173 4.719 21.520 1.00 24.52 ? 41 LEU B CD1 1 ATOM 5906 C CD2 . LEU B 1 21 ? 0.481 2.880 21.076 1.00 24.39 ? 41 LEU B CD2 1 ATOM 5907 N N . LYS B 1 22 ? 2.906 6.967 18.532 1.00 28.36 ? 42 LYS B N 1 ATOM 5908 C CA . LYS B 1 22 ? 3.487 7.592 17.339 1.00 28.81 ? 42 LYS B CA 1 ATOM 5909 C C . LYS B 1 22 ? 4.982 7.306 17.205 1.00 29.09 ? 42 LYS B C 1 ATOM 5910 O O . LYS B 1 22 ? 5.479 7.072 16.104 1.00 29.74 ? 42 LYS B O 1 ATOM 5911 C CB . LYS B 1 22 ? 3.272 9.107 17.382 1.00 28.94 ? 42 LYS B CB 1 ATOM 5912 C CG . LYS B 1 22 ? 1.847 9.552 17.064 1.00 29.31 ? 42 LYS B CG 1 ATOM 5913 C CD . LYS B 1 22 ? 1.652 11.047 17.335 1.00 29.11 ? 42 LYS B CD 1 ATOM 5914 C CE . LYS B 1 22 ? 0.229 11.492 17.014 1.00 28.61 ? 42 LYS B CE 1 ATOM 5915 N NZ . LYS B 1 22 ? -0.027 12.912 17.390 1.00 27.93 ? 42 LYS B NZ 1 ATOM 5916 N N . ALA B 1 23 ? 5.694 7.314 18.325 1.00 29.27 ? 43 ALA B N 1 ATOM 5917 C CA . ALA B 1 23 ? 7.128 7.045 18.312 1.00 29.46 ? 43 ALA B CA 1 ATOM 5918 C C . ALA B 1 23 ? 7.421 5.613 17.885 1.00 29.74 ? 43 ALA B C 1 ATOM 5919 O O . ALA B 1 23 ? 8.354 5.384 17.116 1.00 29.59 ? 43 ALA B O 1 ATOM 5920 C CB . ALA B 1 23 ? 7.750 7.340 19.683 1.00 29.11 ? 43 ALA B CB 1 ATOM 5921 N N . VAL B 1 24 ? 6.632 4.648 18.371 1.00 29.96 ? 44 VAL B N 1 ATOM 5922 C CA . VAL B 1 24 ? 6.855 3.242 18.008 1.00 30.32 ? 44 VAL B CA 1 ATOM 5923 C C . VAL B 1 24 ? 6.503 3.004 16.536 1.00 31.12 ? 44 VAL B C 1 ATOM 5924 O O . VAL B 1 24 ? 7.220 2.297 15.815 1.00 30.90 ? 44 VAL B O 1 ATOM 5925 C CB . VAL B 1 24 ? 6.077 2.257 18.926 1.00 30.42 ? 44 VAL B CB 1 ATOM 5926 C CG1 . VAL B 1 24 ? 6.172 0.837 18.393 1.00 29.30 ? 44 VAL B CG1 1 ATOM 5927 C CG2 . VAL B 1 24 ? 6.617 2.316 20.360 1.00 29.79 ? 44 VAL B CG2 1 ATOM 5928 N N . HIS B 1 25 ? 5.402 3.618 16.108 1.00 31.85 ? 45 HIS B N 1 ATOM 5929 C CA . HIS B 1 25 ? 4.930 3.532 14.738 1.00 32.65 ? 45 HIS B CA 1 ATOM 5930 C C . HIS B 1 25 ? 5.932 4.153 13.757 1.00 32.74 ? 45 HIS B C 1 ATOM 5931 O O . HIS B 1 25 ? 6.218 3.564 12.721 1.00 32.44 ? 45 HIS B O 1 ATOM 5932 C CB . HIS B 1 25 ? 3.582 4.238 14.615 1.00 32.98 ? 45 HIS B CB 1 ATOM 5933 C CG . HIS B 1 25 ? 2.825 3.884 13.377 1.00 34.99 ? 45 HIS B CG 1 ATOM 5934 N ND1 . HIS B 1 25 ? 2.574 4.793 12.371 1.00 38.06 ? 45 HIS B ND1 1 ATOM 5935 C CD2 . HIS B 1 25 ? 2.259 2.721 12.983 1.00 36.74 ? 45 HIS B CD2 1 ATOM 5936 C CE1 . HIS B 1 25 ? 1.886 4.204 11.409 1.00 38.30 ? 45 HIS B CE1 1 ATOM 5937 N NE2 . HIS B 1 25 ? 1.678 2.947 11.758 1.00 38.95 ? 45 HIS B NE2 1 ATOM 5938 N N . SER B 1 26 ? 6.442 5.339 14.089 1.00 33.03 ? 46 SER B N 1 ATOM 5939 C CA A SER B 1 26 ? 7.441 6.014 13.252 0.60 33.31 ? 46 SER B CA 1 ATOM 5940 C CA B SER B 1 26 ? 7.442 6.023 13.268 0.40 33.21 ? 46 SER B CA 1 ATOM 5941 C C . SER B 1 26 ? 8.686 5.153 13.084 1.00 33.38 ? 46 SER B C 1 ATOM 5942 O O . SER B 1 26 ? 9.176 4.971 11.969 1.00 33.80 ? 46 SER B O 1 ATOM 5943 C CB A SER B 1 26 ? 7.841 7.368 13.843 0.60 33.31 ? 46 SER B CB 1 ATOM 5944 C CB B SER B 1 26 ? 7.829 7.353 13.921 0.40 33.19 ? 46 SER B CB 1 ATOM 5945 O OG A SER B 1 26 ? 6.868 8.353 13.557 0.60 33.96 ? 46 SER B OG 1 ATOM 5946 O OG B SER B 1 26 ? 8.836 8.025 13.188 0.40 33.16 ? 46 SER B OG 1 ATOM 5947 N N . PHE B 1 27 ? 9.185 4.622 14.190 1.00 33.39 ? 47 PHE B N 1 ATOM 5948 C CA . PHE B 1 27 ? 10.376 3.775 14.180 1.00 33.62 ? 47 PHE B CA 1 ATOM 5949 C C . PHE B 1 27 ? 10.226 2.582 13.226 1.00 33.81 ? 47 PHE B C 1 ATOM 5950 O O . PHE B 1 27 ? 11.104 2.313 12.402 1.00 33.41 ? 47 PHE B O 1 ATOM 5951 C CB . PHE B 1 27 ? 10.666 3.310 15.609 1.00 33.50 ? 47 PHE B CB 1 ATOM 5952 C CG . PHE B 1 27 ? 11.686 2.235 15.701 1.00 34.05 ? 47 PHE B CG 1 ATOM 5953 C CD1 . PHE B 1 27 ? 13.031 2.528 15.568 1.00 35.25 ? 47 PHE B CD1 1 ATOM 5954 C CD2 . PHE B 1 27 ? 11.304 0.924 15.928 1.00 35.15 ? 47 PHE B CD2 1 ATOM 5955 C CE1 . PHE B 1 27 ? 13.986 1.528 15.655 1.00 36.08 ? 47 PHE B CE1 1 ATOM 5956 C CE2 . PHE B 1 27 ? 12.244 -0.084 16.015 1.00 36.00 ? 47 PHE B CE2 1 ATOM 5957 C CZ . PHE B 1 27 ? 13.590 0.214 15.885 1.00 36.65 ? 47 PHE B CZ 1 ATOM 5958 N N . LEU B 1 28 ? 9.100 1.882 13.329 1.00 33.82 ? 48 LEU B N 1 ATOM 5959 C CA . LEU B 1 28 ? 8.849 0.725 12.483 1.00 33.51 ? 48 LEU B CA 1 ATOM 5960 C C . LEU B 1 28 ? 8.712 1.158 11.020 1.00 33.90 ? 48 LEU B C 1 ATOM 5961 O O . LEU B 1 28 ? 9.243 0.508 10.124 1.00 34.13 ? 48 LEU B O 1 ATOM 5962 C CB . LEU B 1 28 ? 7.605 -0.035 12.963 1.00 33.33 ? 48 LEU B CB 1 ATOM 5963 C CG . LEU B 1 28 ? 7.738 -0.699 14.343 1.00 32.30 ? 48 LEU B CG 1 ATOM 5964 C CD1 . LEU B 1 28 ? 6.392 -1.180 14.861 1.00 31.74 ? 48 LEU B CD1 1 ATOM 5965 C CD2 . LEU B 1 28 ? 8.738 -1.846 14.303 1.00 30.62 ? 48 LEU B CD2 1 ATOM 5966 N N . TRP B 1 29 ? 8.021 2.266 10.783 1.00 34.44 ? 49 TRP B N 1 ATOM 5967 C CA . TRP B 1 29 ? 7.848 2.773 9.423 1.00 34.81 ? 49 TRP B CA 1 ATOM 5968 C C . TRP B 1 29 ? 9.153 3.250 8.782 1.00 34.86 ? 49 TRP B C 1 ATOM 5969 O O . TRP B 1 29 ? 9.252 3.251 7.567 1.00 35.02 ? 49 TRP B O 1 ATOM 5970 C CB . TRP B 1 29 ? 6.800 3.883 9.370 1.00 35.00 ? 49 TRP B CB 1 ATOM 5971 C CG . TRP B 1 29 ? 5.450 3.364 9.082 1.00 36.07 ? 49 TRP B CG 1 ATOM 5972 C CD1 . TRP B 1 29 ? 4.660 2.632 9.925 1.00 37.75 ? 49 TRP B CD1 1 ATOM 5973 C CD2 . TRP B 1 29 ? 4.719 3.499 7.861 1.00 36.63 ? 49 TRP B CD2 1 ATOM 5974 N NE1 . TRP B 1 29 ? 3.476 2.313 9.304 1.00 38.11 ? 49 TRP B NE1 1 ATOM 5975 C CE2 . TRP B 1 29 ? 3.483 2.834 8.038 1.00 36.90 ? 49 TRP B CE2 1 ATOM 5976 C CE3 . TRP B 1 29 ? 4.980 4.125 6.637 1.00 36.95 ? 49 TRP B CE3 1 ATOM 5977 C CZ2 . TRP B 1 29 ? 2.506 2.779 7.036 1.00 36.75 ? 49 TRP B CZ2 1 ATOM 5978 C CZ3 . TRP B 1 29 ? 4.006 4.067 5.635 1.00 36.69 ? 49 TRP B CZ3 1 ATOM 5979 C CH2 . TRP B 1 29 ? 2.788 3.396 5.843 1.00 36.69 ? 49 TRP B CH2 1 ATOM 5980 N N . SER B 1 30 ? 10.141 3.639 9.589 1.00 34.92 ? 50 SER B N 1 ATOM 5981 C CA . SER B 1 30 ? 11.454 4.048 9.067 1.00 34.85 ? 50 SER B CA 1 ATOM 5982 C C . SER B 1 30 ? 12.297 2.862 8.585 1.00 35.06 ? 50 SER B C 1 ATOM 5983 O O . SER B 1 30 ? 13.320 3.056 7.922 1.00 35.19 ? 50 SER B O 1 ATOM 5984 C CB . SER B 1 30 ? 12.233 4.827 10.117 1.00 34.63 ? 50 SER B CB 1 ATOM 5985 O OG . SER B 1 30 ? 12.817 3.957 11.067 1.00 34.92 ? 50 SER B OG 1 ATOM 5986 N N . LYS B 1 31 ? 11.883 1.644 8.933 1.00 35.00 ? 51 LYS B N 1 ATOM 5987 C CA . LYS B 1 31 ? 12.529 0.439 8.435 1.00 35.04 ? 51 LYS B CA 1 ATOM 5988 C C . LYS B 1 31 ? 11.907 0.031 7.097 1.00 34.91 ? 51 LYS B C 1 ATOM 5989 O O . LYS B 1 31 ? 10.862 -0.631 7.051 1.00 34.40 ? 51 LYS B O 1 ATOM 5990 C CB . LYS B 1 31 ? 12.404 -0.685 9.455 1.00 35.15 ? 51 LYS B CB 1 ATOM 5991 C CG . LYS B 1 31 ? 13.116 -0.393 10.751 1.00 36.09 ? 51 LYS B CG 1 ATOM 5992 C CD . LYS B 1 31 ? 13.150 -1.630 11.643 1.00 37.90 ? 51 LYS B CD 1 ATOM 5993 C CE . LYS B 1 31 ? 14.111 -1.449 12.794 1.00 38.80 ? 51 LYS B CE 1 ATOM 5994 N NZ . LYS B 1 31 ? 15.526 -1.309 12.329 1.00 40.60 ? 51 LYS B NZ 1 ATOM 5995 N N . LYS B 1 32 ? 12.555 0.440 6.007 1.00 34.54 ? 52 LYS B N 1 ATOM 5996 C CA . LYS B 1 32 ? 11.982 0.290 4.663 1.00 34.31 ? 52 LYS B CA 1 ATOM 5997 C C . LYS B 1 32 ? 11.815 -1.164 4.247 1.00 33.84 ? 52 LYS B C 1 ATOM 5998 O O . LYS B 1 32 ? 10.921 -1.492 3.472 1.00 33.50 ? 52 LYS B O 1 ATOM 5999 C CB . LYS B 1 32 ? 12.840 1.033 3.632 1.00 34.58 ? 52 LYS B CB 1 ATOM 6000 N N . GLU B 1 33 ? 12.665 -2.040 4.773 1.00 33.52 ? 53 GLU B N 1 ATOM 6001 C CA . GLU B 1 33 ? 12.589 -3.465 4.438 1.00 33.46 ? 53 GLU B CA 1 ATOM 6002 C C . GLU B 1 33 ? 11.328 -4.158 4.985 1.00 32.97 ? 53 GLU B C 1 ATOM 6003 O O . GLU B 1 33 ? 11.005 -5.262 4.565 1.00 32.81 ? 53 GLU B O 1 ATOM 6004 C CB . GLU B 1 33 ? 13.865 -4.214 4.875 1.00 33.52 ? 53 GLU B CB 1 ATOM 6005 C CG . GLU B 1 33 ? 14.009 -4.519 6.380 1.00 34.82 ? 53 GLU B CG 1 ATOM 6006 C CD . GLU B 1 33 ? 14.423 -3.316 7.210 1.00 36.49 ? 53 GLU B CD 1 ATOM 6007 O OE1 . GLU B 1 33 ? 14.402 -2.181 6.684 1.00 37.43 ? 53 GLU B OE1 1 ATOM 6008 O OE2 . GLU B 1 33 ? 14.761 -3.504 8.402 1.00 38.06 ? 53 GLU B OE2 1 ATOM 6009 N N . LEU B 1 34 ? 10.623 -3.517 5.913 1.00 32.69 ? 54 LEU B N 1 ATOM 6010 C CA . LEU B 1 34 ? 9.354 -4.048 6.419 1.00 32.39 ? 54 LEU B CA 1 ATOM 6011 C C . LEU B 1 34 ? 8.188 -3.868 5.432 1.00 31.94 ? 54 LEU B C 1 ATOM 6012 O O . LEU B 1 34 ? 7.171 -4.546 5.551 1.00 31.90 ? 54 LEU B O 1 ATOM 6013 C CB . LEU B 1 34 ? 9.008 -3.405 7.767 1.00 32.51 ? 54 LEU B CB 1 ATOM 6014 C CG . LEU B 1 34 ? 9.986 -3.686 8.922 1.00 32.46 ? 54 LEU B CG 1 ATOM 6015 C CD1 . LEU B 1 34 ? 9.467 -3.090 10.219 1.00 32.90 ? 54 LEU B CD1 1 ATOM 6016 C CD2 . LEU B 1 34 ? 10.241 -5.183 9.112 1.00 32.07 ? 54 LEU B CD2 1 ATOM 6017 N N . ARG B 1 35 ? 8.339 -2.960 4.469 1.00 31.65 ? 55 ARG B N 1 ATOM 6018 C CA . ARG B 1 35 ? 7.324 -2.717 3.438 1.00 31.41 ? 55 ARG B CA 1 ATOM 6019 C C . ARG B 1 35 ? 5.945 -2.435 4.037 1.00 31.05 ? 55 ARG B C 1 ATOM 6020 O O . ARG B 1 35 ? 4.922 -2.883 3.516 1.00 30.93 ? 55 ARG B O 1 ATOM 6021 C CB . ARG B 1 35 ? 7.231 -3.899 2.468 1.00 31.63 ? 55 ARG B CB 1 ATOM 6022 C CG . ARG B 1 35 ? 8.536 -4.249 1.755 1.00 33.08 ? 55 ARG B CG 1 ATOM 6023 C CD . ARG B 1 35 ? 8.341 -5.347 0.699 1.00 34.73 ? 55 ARG B CD 1 ATOM 6024 N NE . ARG B 1 35 ? 7.281 -5.021 -0.264 1.00 37.61 ? 55 ARG B NE 1 ATOM 6025 C CZ . ARG B 1 35 ? 7.477 -4.391 -1.423 1.00 38.63 ? 55 ARG B CZ 1 ATOM 6026 N N . LEU B 1 36 ? 5.922 -1.661 5.115 1.00 30.51 ? 56 LEU B N 1 ATOM 6027 C CA . LEU B 1 36 ? 4.685 -1.413 5.837 1.00 30.11 ? 56 LEU B CA 1 ATOM 6028 C C . LEU B 1 36 ? 3.716 -0.564 5.031 1.00 30.07 ? 56 LEU B C 1 ATOM 6029 O O . LEU B 1 36 ? 4.116 0.337 4.299 1.00 30.46 ? 56 LEU B O 1 ATOM 6030 C CB . LEU B 1 36 ? 4.974 -0.756 7.186 1.00 29.86 ? 56 LEU B CB 1 ATOM 6031 C CG . LEU B 1 36 ? 5.777 -1.609 8.170 1.00 29.11 ? 56 LEU B CG 1 ATOM 6032 C CD1 . LEU B 1 36 ? 6.011 -0.839 9.460 1.00 28.97 ? 56 LEU B CD1 1 ATOM 6033 C CD2 . LEU B 1 36 ? 5.099 -2.937 8.448 1.00 27.24 ? 56 LEU B CD2 1 ATOM 6034 N N . GLN B 1 37 ? 2.433 -0.882 5.165 1.00 29.79 ? 57 GLN B N 1 ATOM 6035 C CA . GLN B 1 37 ? 1.359 -0.120 4.559 1.00 29.40 ? 57 GLN B CA 1 ATOM 6036 C C . GLN B 1 37 ? 0.266 0.101 5.623 1.00 29.68 ? 57 GLN B C 1 ATOM 6037 O O . GLN B 1 37 ? 0.201 -0.639 6.609 1.00 29.83 ? 57 GLN B O 1 ATOM 6038 C CB . GLN B 1 37 ? 0.791 -0.875 3.360 1.00 29.40 ? 57 GLN B CB 1 ATOM 6039 C CG . GLN B 1 37 ? 1.815 -1.287 2.320 1.00 29.11 ? 57 GLN B CG 1 ATOM 6040 C CD . GLN B 1 37 ? 1.174 -1.934 1.108 1.00 29.30 ? 57 GLN B CD 1 ATOM 6041 O OE1 . GLN B 1 37 ? 0.188 -1.438 0.584 1.00 29.79 ? 57 GLN B OE1 1 ATOM 6042 N NE2 . GLN B 1 37 ? 1.726 -3.053 0.667 1.00 29.98 ? 57 GLN B NE2 1 ATOM 6043 N N . PRO B 1 38 ? -0.600 1.112 5.432 1.00 29.60 ? 58 PRO B N 1 ATOM 6044 C CA . PRO B 1 38 ? -1.645 1.360 6.431 1.00 29.53 ? 58 PRO B CA 1 ATOM 6045 C C . PRO B 1 38 ? -2.615 0.189 6.609 1.00 29.59 ? 58 PRO B C 1 ATOM 6046 O O . PRO B 1 38 ? -2.822 -0.595 5.684 1.00 29.46 ? 58 PRO B O 1 ATOM 6047 C CB . PRO B 1 38 ? -2.384 2.590 5.884 1.00 29.64 ? 58 PRO B CB 1 ATOM 6048 C CG . PRO B 1 38 ? -1.494 3.176 4.831 1.00 29.64 ? 58 PRO B CG 1 ATOM 6049 C CD . PRO B 1 38 ? -0.660 2.061 4.307 1.00 29.77 ? 58 PRO B CD 1 ATOM 6050 N N . SER B 1 39 ? -3.195 0.076 7.801 1.00 29.88 ? 59 SER B N 1 ATOM 6051 C CA . SER B 1 39 ? -4.241 -0.906 8.063 1.00 30.43 ? 59 SER B CA 1 ATOM 6052 C C . SER B 1 39 ? -5.384 -0.752 7.062 1.00 30.60 ? 59 SER B C 1 ATOM 6053 O O . SER B 1 39 ? -5.989 -1.739 6.667 1.00 31.05 ? 59 SER B O 1 ATOM 6054 C CB . SER B 1 39 ? -4.800 -0.753 9.484 1.00 30.56 ? 59 SER B CB 1 ATOM 6055 O OG . SER B 1 39 ? -5.674 0.373 9.582 1.00 31.46 ? 59 SER B OG 1 ATOM 6056 N N . SER B 1 40 ? -5.656 0.486 6.646 1.00 30.77 ? 60 SER B N 1 ATOM 6057 C CA . SER B 1 40 ? -6.808 0.789 5.792 1.00 30.95 ? 60 SER B CA 1 ATOM 6058 C C . SER B 1 40 ? -6.665 0.366 4.326 1.00 30.99 ? 60 SER B C 1 ATOM 6059 O O . SER B 1 40 ? -7.650 0.367 3.601 1.00 30.89 ? 60 SER B O 1 ATOM 6060 C CB . SER B 1 40 ? -7.154 2.282 5.872 1.00 30.78 ? 60 SER B CB 1 ATOM 6061 O OG . SER B 1 40 ? -6.069 3.106 5.490 1.00 31.40 ? 60 SER B OG 1 ATOM 6062 N N . THR B 1 41 ? -5.451 0.031 3.884 1.00 31.30 ? 61 THR B N 1 ATOM 6063 C CA . THR B 1 41 ? -5.242 -0.426 2.508 1.00 31.14 ? 61 THR B CA 1 ATOM 6064 C C . THR B 1 41 ? -5.969 -1.755 2.315 1.00 31.29 ? 61 THR B C 1 ATOM 6065 O O . THR B 1 41 ? -5.763 -2.690 3.090 1.00 30.87 ? 61 THR B O 1 ATOM 6066 C CB . THR B 1 41 ? -3.750 -0.599 2.203 1.00 31.49 ? 61 THR B CB 1 ATOM 6067 O OG1 . THR B 1 41 ? -3.075 0.629 2.488 1.00 31.63 ? 61 THR B OG1 1 ATOM 6068 C CG2 . THR B 1 41 ? -3.512 -1.000 0.742 1.00 30.55 ? 61 THR B CG2 1 ATOM 6069 N N . THR B 1 42 ? -6.815 -1.833 1.285 1.00 31.27 ? 62 THR B N 1 ATOM 6070 C CA . THR B 1 42 ? -7.787 -2.927 1.150 1.00 31.34 ? 62 THR B CA 1 ATOM 6071 C C . THR B 1 42 ? -7.240 -4.106 0.339 1.00 30.90 ? 62 THR B C 1 ATOM 6072 O O . THR B 1 42 ? -7.792 -4.476 -0.717 1.00 30.59 ? 62 THR B O 1 ATOM 6073 C CB . THR B 1 42 ? -9.113 -2.431 0.498 1.00 31.77 ? 62 THR B CB 1 ATOM 6074 O OG1 . THR B 1 42 ? -8.841 -1.968 -0.827 1.00 33.20 ? 62 THR B OG1 1 ATOM 6075 C CG2 . THR B 1 42 ? -9.730 -1.294 1.309 1.00 31.65 ? 62 THR B CG2 1 ATOM 6076 N N . THR B 1 43 ? -6.140 -4.665 0.839 1.00 29.99 ? 63 THR B N 1 ATOM 6077 C CA . THR B 1 43 ? -5.593 -5.923 0.366 1.00 29.48 ? 63 THR B CA 1 ATOM 6078 C C . THR B 1 43 ? -5.062 -6.660 1.581 1.00 28.87 ? 63 THR B C 1 ATOM 6079 O O . THR B 1 43 ? -4.626 -6.034 2.541 1.00 28.19 ? 63 THR B O 1 ATOM 6080 C CB . THR B 1 43 ? -4.427 -5.735 -0.648 1.00 29.52 ? 63 THR B CB 1 ATOM 6081 O OG1 . THR B 1 43 ? -4.003 -7.013 -1.118 1.00 29.22 ? 63 THR B OG1 1 ATOM 6082 C CG2 . THR B 1 43 ? -3.225 -5.043 -0.002 1.00 29.92 ? 63 THR B CG2 1 ATOM 6083 N N . MET B 1 44 ? -5.101 -7.987 1.531 1.00 28.59 ? 64 MET B N 1 ATOM 6084 C CA . MET B 1 44 ? -4.518 -8.810 2.579 1.00 28.21 ? 64 MET B CA 1 ATOM 6085 C C . MET B 1 44 ? -3.021 -9.008 2.331 1.00 28.10 ? 64 MET B C 1 ATOM 6086 O O . MET B 1 44 ? -2.278 -9.362 3.250 1.00 28.16 ? 64 MET B O 1 ATOM 6087 C CB . MET B 1 44 ? -5.232 -10.159 2.633 1.00 28.40 ? 64 MET B CB 1 ATOM 6088 C CG . MET B 1 44 ? -6.741 -10.072 2.858 1.00 28.45 ? 64 MET B CG 1 ATOM 6089 S SD . MET B 1 44 ? -7.207 -9.507 4.517 1.00 29.13 ? 64 MET B SD 1 ATOM 6090 C CE . MET B 1 44 ? -7.149 -7.724 4.345 1.00 28.13 ? 64 MET B CE 1 ATOM 6091 N N . ALA B 1 45 ? -2.576 -8.771 1.095 1.00 27.82 ? 65 ALA B N 1 ATOM 6092 C CA . ALA B 1 45 ? -1.178 -9.000 0.707 1.00 27.87 ? 65 ALA B CA 1 ATOM 6093 C C . ALA B 1 45 ? -0.327 -7.769 0.996 1.00 27.73 ? 65 ALA B C 1 ATOM 6094 O O . ALA B 1 45 ? 0.251 -7.174 0.096 1.00 28.02 ? 65 ALA B O 1 ATOM 6095 C CB . ALA B 1 45 ? -1.077 -9.392 -0.776 1.00 27.49 ? 65 ALA B CB 1 ATOM 6096 N N . LYS B 1 46 ? -0.264 -7.401 2.268 1.00 27.88 ? 66 LYS B N 1 ATOM 6097 C CA . LYS B 1 46 ? 0.479 -6.236 2.722 1.00 27.43 ? 66 LYS B CA 1 ATOM 6098 C C . LYS B 1 46 ? 1.076 -6.562 4.081 1.00 27.19 ? 66 LYS B C 1 ATOM 6099 O O . LYS B 1 46 ? 0.599 -7.453 4.786 1.00 26.84 ? 66 LYS B O 1 ATOM 6100 C CB . LYS B 1 46 ? -0.438 -5.024 2.851 1.00 27.95 ? 66 LYS B CB 1 ATOM 6101 C CG . LYS B 1 46 ? -1.567 -5.226 3.860 1.00 28.49 ? 66 LYS B CG 1 ATOM 6102 C CD . LYS B 1 46 ? -2.528 -4.046 3.955 1.00 30.22 ? 66 LYS B CD 1 ATOM 6103 C CE . LYS B 1 46 ? -3.580 -4.336 5.044 1.00 30.25 ? 66 LYS B CE 1 ATOM 6104 N NZ . LYS B 1 46 ? -4.546 -3.254 5.213 1.00 31.96 ? 66 LYS B NZ 1 ATOM 6105 N N . ASN B 1 47 ? 2.141 -5.854 4.423 1.00 26.71 ? 67 ASN B N 1 ATOM 6106 C CA . ASN B 1 47 ? 2.677 -5.867 5.768 1.00 26.21 ? 67 ASN B CA 1 ATOM 6107 C C . ASN B 1 47 ? 2.133 -4.632 6.488 1.00 25.74 ? 67 ASN B C 1 ATOM 6108 O O . ASN B 1 47 ? 2.148 -3.530 5.931 1.00 25.86 ? 67 ASN B O 1 ATOM 6109 C CB . ASN B 1 47 ? 4.201 -5.823 5.732 1.00 26.47 ? 67 ASN B CB 1 ATOM 6110 C CG . ASN B 1 47 ? 4.805 -7.011 5.023 1.00 25.22 ? 67 ASN B CG 1 ATOM 6111 O OD1 . ASN B 1 47 ? 4.144 -8.018 4.787 1.00 25.82 ? 67 ASN B OD1 1 ATOM 6112 N ND2 . ASN B 1 47 ? 6.073 -6.898 4.685 1.00 24.65 ? 67 ASN B ND2 1 ATOM 6113 N N . THR B 1 48 ? 1.638 -4.823 7.706 1.00 25.00 ? 68 THR B N 1 ATOM 6114 C CA A THR B 1 48 ? 1.042 -3.742 8.470 0.60 24.74 ? 68 THR B CA 1 ATOM 6115 C CA B THR B 1 48 ? 1.015 -3.750 8.477 0.40 24.76 ? 68 THR B CA 1 ATOM 6116 C C . THR B 1 48 ? 1.207 -3.999 9.964 1.00 24.64 ? 68 THR B C 1 ATOM 6117 O O . THR B 1 48 ? 1.224 -5.150 10.404 1.00 24.44 ? 68 THR B O 1 ATOM 6118 C CB A THR B 1 48 ? -0.463 -3.581 8.114 0.60 24.78 ? 68 THR B CB 1 ATOM 6119 C CB B THR B 1 48 ? -0.512 -3.662 8.212 0.40 24.77 ? 68 THR B CB 1 ATOM 6120 O OG1 A THR B 1 48 ? -0.953 -2.338 8.626 0.60 24.26 ? 68 THR B OG1 1 ATOM 6121 O OG1 B THR B 1 48 ? -1.146 -4.876 8.633 0.40 24.70 ? 68 THR B OG1 1 ATOM 6122 C CG2 A THR B 1 48 ? -1.287 -4.727 8.679 0.60 24.68 ? 68 THR B CG2 1 ATOM 6123 C CG2 B THR B 1 48 ? -0.808 -3.426 6.739 0.40 24.33 ? 68 THR B CG2 1 ATOM 6124 N N . VAL B 1 49 ? 1.337 -2.921 10.733 1.00 24.66 ? 69 VAL B N 1 ATOM 6125 C CA . VAL B 1 49 ? 1.416 -3.016 12.189 1.00 24.85 ? 69 VAL B CA 1 ATOM 6126 C C . VAL B 1 49 ? -0.022 -3.064 12.720 1.00 24.96 ? 69 VAL B C 1 ATOM 6127 O O . VAL B 1 49 ? -0.754 -2.085 12.624 1.00 25.26 ? 69 VAL B O 1 ATOM 6128 C CB . VAL B 1 49 ? 2.195 -1.826 12.809 1.00 24.68 ? 69 VAL B CB 1 ATOM 6129 C CG1 . VAL B 1 49 ? 2.378 -2.028 14.313 1.00 24.70 ? 69 VAL B CG1 1 ATOM 6130 C CG2 . VAL B 1 49 ? 3.563 -1.671 12.131 1.00 24.92 ? 69 VAL B CG2 1 ATOM 6131 N N . PHE B 1 50 ? -0.424 -4.217 13.243 1.00 25.23 ? 70 PHE B N 1 ATOM 6132 C CA . PHE B 1 50 ? -1.798 -4.447 13.677 1.00 25.24 ? 70 PHE B CA 1 ATOM 6133 C C . PHE B 1 50 ? -2.054 -3.852 15.068 1.00 25.50 ? 70 PHE B C 1 ATOM 6134 O O . PHE B 1 50 ? -3.099 -3.267 15.318 1.00 25.79 ? 70 PHE B O 1 ATOM 6135 C CB . PHE B 1 50 ? -2.099 -5.949 13.679 1.00 25.06 ? 70 PHE B CB 1 ATOM 6136 C CG . PHE B 1 50 ? -3.523 -6.282 14.010 1.00 26.20 ? 70 PHE B CG 1 ATOM 6137 C CD1 . PHE B 1 50 ? -4.547 -5.979 13.123 1.00 25.79 ? 70 PHE B CD1 1 ATOM 6138 C CD2 . PHE B 1 50 ? -3.850 -6.887 15.218 1.00 26.67 ? 70 PHE B CD2 1 ATOM 6139 C CE1 . PHE B 1 50 ? -5.864 -6.285 13.431 1.00 25.63 ? 70 PHE B CE1 1 ATOM 6140 C CE2 . PHE B 1 50 ? -5.183 -7.183 15.530 1.00 26.80 ? 70 PHE B CE2 1 ATOM 6141 C CZ . PHE B 1 50 ? -6.178 -6.883 14.635 1.00 25.50 ? 70 PHE B CZ 1 ATOM 6142 N N . LEU B 1 51 ? -1.095 -4.001 15.969 1.00 25.55 ? 71 LEU B N 1 ATOM 6143 C CA . LEU B 1 51 ? -1.292 -3.618 17.355 1.00 25.61 ? 71 LEU B CA 1 ATOM 6144 C C . LEU B 1 51 ? 0.003 -3.128 17.970 1.00 25.59 ? 71 LEU B C 1 ATOM 6145 O O . LEU B 1 51 ? 1.053 -3.727 17.755 1.00 25.13 ? 71 LEU B O 1 ATOM 6146 C CB . LEU B 1 51 ? -1.815 -4.820 18.139 1.00 25.97 ? 71 LEU B CB 1 ATOM 6147 C CG . LEU B 1 51 ? -1.538 -4.943 19.638 1.00 26.60 ? 71 LEU B CG 1 ATOM 6148 C CD1 . LEU B 1 51 ? -2.261 -3.846 20.396 1.00 27.61 ? 71 LEU B CD1 1 ATOM 6149 C CD2 . LEU B 1 51 ? -1.977 -6.321 20.110 1.00 26.53 ? 71 LEU B CD2 1 ATOM 6150 N N . ILE B 1 52 ? -0.094 -2.030 18.720 1.00 25.50 ? 72 ILE B N 1 ATOM 6151 C CA . ILE B 1 52 ? 0.979 -1.561 19.587 1.00 25.76 ? 72 ILE B CA 1 ATOM 6152 C C . ILE B 1 52 ? 0.401 -1.255 20.977 1.00 25.93 ? 72 ILE B C 1 ATOM 6153 O O . ILE B 1 52 ? -0.553 -0.486 21.096 1.00 26.24 ? 72 ILE B O 1 ATOM 6154 C CB . ILE B 1 52 ? 1.637 -0.262 19.076 1.00 25.63 ? 72 ILE B CB 1 ATOM 6155 C CG1 . ILE B 1 52 ? 2.199 -0.433 17.663 1.00 25.56 ? 72 ILE B CG1 1 ATOM 6156 C CG2 . ILE B 1 52 ? 2.748 0.162 20.040 1.00 25.57 ? 72 ILE B CG2 1 ATOM 6157 C CD1 . ILE B 1 52 ? 2.534 0.876 16.990 1.00 24.07 ? 72 ILE B CD1 1 ATOM 6158 N N . GLU B 1 53 ? 0.986 -1.853 22.008 1.00 26.00 ? 73 GLU B N 1 ATOM 6159 C CA . GLU B 1 53 ? 0.637 -1.562 23.401 1.00 26.22 ? 73 GLU B CA 1 ATOM 6160 C C . GLU B 1 53 ? 1.889 -1.731 24.267 1.00 26.29 ? 73 GLU B C 1 ATOM 6161 O O . GLU B 1 53 ? 2.884 -2.283 23.812 1.00 25.34 ? 73 GLU B O 1 ATOM 6162 C CB . GLU B 1 53 ? -0.479 -2.498 23.883 1.00 26.27 ? 73 GLU B CB 1 ATOM 6163 C CG . GLU B 1 53 ? -0.102 -3.979 23.858 1.00 26.31 ? 73 GLU B CG 1 ATOM 6164 C CD . GLU B 1 53 ? -1.264 -4.924 24.153 1.00 27.33 ? 73 GLU B CD 1 ATOM 6165 O OE1 . GLU B 1 53 ? -2.431 -4.464 24.228 1.00 29.05 ? 73 GLU B OE1 1 ATOM 6166 O OE2 . GLU B 1 53 ? -0.996 -6.140 24.301 1.00 26.61 ? 73 GLU B OE2 1 ATOM 6167 N N . MET B 1 54 ? 1.842 -1.249 25.508 1.00 26.74 ? 74 MET B N 1 ATOM 6168 C CA . MET B 1 54 ? 3.005 -1.354 26.399 1.00 26.68 ? 74 MET B CA 1 ATOM 6169 C C . MET B 1 54 ? 3.224 -2.813 26.795 1.00 26.95 ? 74 MET B C 1 ATOM 6170 O O . MET B 1 54 ? 2.265 -3.556 27.042 1.00 26.48 ? 74 MET B O 1 ATOM 6171 C CB . MET B 1 54 ? 2.838 -0.461 27.632 1.00 26.68 ? 74 MET B CB 1 ATOM 6172 C CG . MET B 1 54 ? 4.003 -0.490 28.621 1.00 27.11 ? 74 MET B CG 1 ATOM 6173 S SD . MET B 1 54 ? 3.921 -1.846 29.823 1.00 29.81 ? 74 MET B SD 1 ATOM 6174 C CE . MET B 1 54 ? 2.672 -1.259 30.971 1.00 29.13 ? 74 MET B CE 1 ATOM 6175 N N . LEU B 1 55 ? 4.497 -3.211 26.821 1.00 27.07 ? 75 LEU B N 1 ATOM 6176 C CA . LEU B 1 55 ? 4.916 -4.555 27.185 1.00 27.43 ? 75 LEU B CA 1 ATOM 6177 C C . LEU B 1 55 ? 5.536 -4.508 28.583 1.00 27.58 ? 75 LEU B C 1 ATOM 6178 O O . LEU B 1 55 ? 6.629 -3.964 28.766 1.00 27.65 ? 75 LEU B O 1 ATOM 6179 C CB . LEU B 1 55 ? 5.948 -5.081 26.169 1.00 27.71 ? 75 LEU B CB 1 ATOM 6180 C CG . LEU B 1 55 ? 6.417 -6.534 26.326 1.00 27.96 ? 75 LEU B CG 1 ATOM 6181 C CD1 . LEU B 1 55 ? 5.253 -7.490 26.171 1.00 27.79 ? 75 LEU B CD1 1 ATOM 6182 C CD2 . LEU B 1 55 ? 7.533 -6.880 25.334 1.00 26.73 ? 75 LEU B CD2 1 ATOM 6183 N N . LEU B 1 56 ? 4.845 -5.087 29.560 1.00 27.45 ? 76 LEU B N 1 ATOM 6184 C CA . LEU B 1 56 ? 5.278 -5.021 30.951 1.00 27.84 ? 76 LEU B CA 1 ATOM 6185 C C . LEU B 1 56 ? 6.690 -5.605 31.142 1.00 27.68 ? 76 LEU B C 1 ATOM 6186 O O . LEU B 1 56 ? 6.991 -6.665 30.608 1.00 27.31 ? 76 LEU B O 1 ATOM 6187 C CB . LEU B 1 56 ? 4.274 -5.749 31.858 1.00 27.90 ? 76 LEU B CB 1 ATOM 6188 C CG . LEU B 1 56 ? 4.152 -5.248 33.300 1.00 29.13 ? 76 LEU B CG 1 ATOM 6189 C CD1 . LEU B 1 56 ? 3.958 -3.732 33.368 1.00 28.16 ? 76 LEU B CD1 1 ATOM 6190 C CD2 . LEU B 1 56 ? 3.000 -5.966 33.995 1.00 30.13 ? 76 LEU B CD2 1 ATOM 6191 N N . PRO B 1 57 ? 7.557 -4.908 31.894 1.00 27.87 ? 77 PRO B N 1 ATOM 6192 C CA . PRO B 1 57 ? 8.847 -5.492 32.262 1.00 28.17 ? 77 PRO B CA 1 ATOM 6193 C C . PRO B 1 57 ? 8.692 -6.703 33.171 1.00 28.50 ? 77 PRO B C 1 ATOM 6194 O O . PRO B 1 57 ? 7.620 -6.949 33.715 1.00 28.56 ? 77 PRO B O 1 ATOM 6195 C CB . PRO B 1 57 ? 9.552 -4.368 33.042 1.00 28.10 ? 77 PRO B CB 1 ATOM 6196 C CG . PRO B 1 57 ? 8.782 -3.149 32.798 1.00 27.90 ? 77 PRO B CG 1 ATOM 6197 C CD . PRO B 1 57 ? 7.386 -3.562 32.468 1.00 28.06 ? 77 PRO B CD 1 ATOM 6198 N N . LYS B 1 58 ? 9.777 -7.435 33.353 1.00 29.21 ? 78 LYS B N 1 ATOM 6199 C CA . LYS B 1 58 ? 9.790 -8.581 34.253 1.00 29.50 ? 78 LYS B CA 1 ATOM 6200 C C . LYS B 1 58 ? 9.494 -8.151 35.691 1.00 29.41 ? 78 LYS B C 1 ATOM 6201 O O . LYS B 1 58 ? 9.946 -7.092 36.139 1.00 28.65 ? 78 LYS B O 1 ATOM 6202 C CB . LYS B 1 58 ? 11.140 -9.290 34.181 1.00 29.81 ? 78 LYS B CB 1 ATOM 6203 C CG . LYS B 1 58 ? 11.397 -9.975 32.844 1.00 31.27 ? 78 LYS B CG 1 ATOM 6204 C CD . LYS B 1 58 ? 12.798 -10.556 32.811 1.00 33.51 ? 78 LYS B CD 1 ATOM 6205 C CE . LYS B 1 58 ? 13.128 -11.153 31.453 1.00 34.99 ? 78 LYS B CE 1 ATOM 6206 N NZ . LYS B 1 58 ? 14.515 -11.722 31.427 1.00 36.71 ? 78 LYS B NZ 1 ATOM 6207 N N . LYS B 1 59 ? 8.726 -8.982 36.396 1.00 29.44 ? 79 LYS B N 1 ATOM 6208 C CA . LYS B 1 59 ? 8.328 -8.695 37.774 1.00 29.74 ? 79 LYS B CA 1 ATOM 6209 C C . LYS B 1 59 ? 9.541 -8.510 38.677 1.00 30.12 ? 79 LYS B C 1 ATOM 6210 O O . LYS B 1 59 ? 9.530 -7.667 39.563 1.00 30.20 ? 79 LYS B O 1 ATOM 6211 C CB . LYS B 1 59 ? 7.443 -9.819 38.324 1.00 29.34 ? 79 LYS B CB 1 ATOM 6212 C CG . LYS B 1 59 ? 6.845 -9.533 39.696 1.00 28.17 ? 79 LYS B CG 1 ATOM 6213 C CD . LYS B 1 59 ? 5.937 -10.656 40.137 1.00 26.58 ? 79 LYS B CD 1 ATOM 6214 C CE . LYS B 1 59 ? 5.365 -10.415 41.521 1.00 25.63 ? 79 LYS B CE 1 ATOM 6215 N NZ . LYS B 1 59 ? 4.394 -11.466 41.883 1.00 24.01 ? 79 LYS B NZ 1 ATOM 6216 N N . TYR B 1 60 ? 10.572 -9.317 38.447 1.00 30.95 ? 80 TYR B N 1 ATOM 6217 C CA . TYR B 1 60 ? 11.823 -9.229 39.202 1.00 31.49 ? 80 TYR B CA 1 ATOM 6218 C C . TYR B 1 60 ? 12.370 -7.803 39.173 1.00 31.19 ? 80 TYR B C 1 ATOM 6219 O O . TYR B 1 60 ? 12.674 -7.220 40.217 1.00 31.34 ? 80 TYR B O 1 ATOM 6220 C CB . TYR B 1 60 ? 12.846 -10.214 38.629 1.00 31.87 ? 80 TYR B CB 1 ATOM 6221 C CG . TYR B 1 60 ? 14.232 -10.031 39.171 1.00 34.18 ? 80 TYR B CG 1 ATOM 6222 C CD1 . TYR B 1 60 ? 14.564 -10.490 40.441 1.00 36.66 ? 80 TYR B CD1 1 ATOM 6223 C CD2 . TYR B 1 60 ? 15.212 -9.388 38.421 1.00 36.27 ? 80 TYR B CD2 1 ATOM 6224 C CE1 . TYR B 1 60 ? 15.835 -10.317 40.955 1.00 37.79 ? 80 TYR B CE1 1 ATOM 6225 C CE2 . TYR B 1 60 ? 16.493 -9.210 38.925 1.00 37.95 ? 80 TYR B CE2 1 ATOM 6226 C CZ . TYR B 1 60 ? 16.794 -9.679 40.193 1.00 39.11 ? 80 TYR B CZ 1 ATOM 6227 O OH . TYR B 1 60 ? 18.054 -9.511 40.705 1.00 41.80 ? 80 TYR B OH 1 ATOM 6228 N N . HIS B 1 61 ? 12.456 -7.238 37.972 1.00 31.06 ? 81 HIS B N 1 ATOM 6229 C CA . HIS B 1 61 ? 12.981 -5.889 37.787 1.00 30.95 ? 81 HIS B CA 1 ATOM 6230 C C . HIS B 1 61 ? 12.025 -4.821 38.328 1.00 30.51 ? 81 HIS B C 1 ATOM 6231 O O . HIS B 1 61 ? 12.464 -3.820 38.904 1.00 30.57 ? 81 HIS B O 1 ATOM 6232 C CB . HIS B 1 61 ? 13.297 -5.630 36.307 1.00 31.23 ? 81 HIS B CB 1 ATOM 6233 C CG . HIS B 1 61 ? 14.382 -6.509 35.753 1.00 32.66 ? 81 HIS B CG 1 ATOM 6234 N ND1 . HIS B 1 61 ? 15.595 -6.687 36.386 1.00 33.83 ? 81 HIS B ND1 1 ATOM 6235 C CD2 . HIS B 1 61 ? 14.440 -7.251 34.620 1.00 33.44 ? 81 HIS B CD2 1 ATOM 6236 C CE1 . HIS B 1 61 ? 16.347 -7.508 35.672 1.00 33.94 ? 81 HIS B CE1 1 ATOM 6237 N NE2 . HIS B 1 61 ? 15.671 -7.860 34.594 1.00 33.64 ? 81 HIS B NE2 1 ATOM 6238 N N . VAL B 1 62 ? 10.721 -5.032 38.150 1.00 29.68 ? 82 VAL B N 1 ATOM 6239 C CA . VAL B 1 62 ? 9.725 -4.080 38.646 1.00 29.00 ? 82 VAL B CA 1 ATOM 6240 C C . VAL B 1 62 ? 9.746 -3.992 40.178 1.00 28.89 ? 82 VAL B C 1 ATOM 6241 O O . VAL B 1 62 ? 9.683 -2.904 40.738 1.00 28.27 ? 82 VAL B O 1 ATOM 6242 C CB . VAL B 1 62 ? 8.281 -4.430 38.164 1.00 28.93 ? 82 VAL B CB 1 ATOM 6243 C CG1 . VAL B 1 62 ? 7.288 -3.430 38.717 1.00 27.99 ? 82 VAL B CG1 1 ATOM 6244 C CG2 . VAL B 1 62 ? 8.204 -4.465 36.635 1.00 27.17 ? 82 VAL B CG2 1 ATOM 6245 N N . LEU B 1 63 ? 9.837 -5.135 40.850 1.00 29.16 ? 83 LEU B N 1 ATOM 6246 C CA . LEU B 1 63 ? 9.865 -5.150 42.317 1.00 29.70 ? 83 LEU B CA 1 ATOM 6247 C C . LEU B 1 63 ? 11.157 -4.551 42.887 1.00 30.14 ? 83 LEU B C 1 ATOM 6248 O O . LEU B 1 63 ? 11.123 -3.909 43.928 1.00 30.17 ? 83 LEU B O 1 ATOM 6249 C CB . LEU B 1 63 ? 9.648 -6.566 42.859 1.00 29.46 ? 83 LEU B CB 1 ATOM 6250 C CG . LEU B 1 63 ? 8.221 -7.114 42.706 1.00 29.86 ? 83 LEU B CG 1 ATOM 6251 C CD1 . LEU B 1 63 ? 8.113 -8.513 43.316 1.00 29.45 ? 83 LEU B CD1 1 ATOM 6252 C CD2 . LEU B 1 63 ? 7.203 -6.172 43.330 1.00 29.82 ? 83 LEU B CD2 1 ATOM 6253 N N . ARG B 1 64 ? 12.283 -4.748 42.204 1.00 30.75 ? 84 ARG B N 1 ATOM 6254 C CA . ARG B 1 64 ? 13.553 -4.146 42.643 1.00 31.22 ? 84 ARG B CA 1 ATOM 6255 C C . ARG B 1 64 ? 13.499 -2.628 42.496 1.00 31.71 ? 84 ARG B C 1 ATOM 6256 O O . ARG B 1 64 ? 14.078 -1.895 43.300 1.00 32.28 ? 84 ARG B O 1 ATOM 6257 C CB . ARG B 1 64 ? 14.739 -4.725 41.864 1.00 31.14 ? 84 ARG B CB 1 ATOM 6258 C CG . ARG B 1 64 ? 15.247 -6.046 42.401 1.00 31.28 ? 84 ARG B CG 1 ATOM 6259 C CD . ARG B 1 64 ? 16.238 -6.683 41.434 1.00 32.62 ? 84 ARG B CD 1 ATOM 6260 N N . PHE B 1 65 ? 12.793 -2.164 41.470 1.00 32.06 ? 85 PHE B N 1 ATOM 6261 C CA . PHE B 1 65 ? 12.540 -0.738 41.269 1.00 32.29 ? 85 PHE B CA 1 ATOM 6262 C C . PHE B 1 65 ? 11.609 -0.160 42.341 1.00 32.49 ? 85 PHE B C 1 ATOM 6263 O O . PHE B 1 65 ? 11.844 0.939 42.854 1.00 32.63 ? 85 PHE B O 1 ATOM 6264 C CB . PHE B 1 65 ? 11.932 -0.530 39.879 1.00 32.29 ? 85 PHE B CB 1 ATOM 6265 C CG . PHE B 1 65 ? 11.362 0.839 39.649 1.00 33.00 ? 85 PHE B CG 1 ATOM 6266 C CD1 . PHE B 1 65 ? 12.170 1.964 39.713 1.00 33.98 ? 85 PHE B CD1 1 ATOM 6267 C CD2 . PHE B 1 65 ? 10.012 1.004 39.336 1.00 33.52 ? 85 PHE B CD2 1 ATOM 6268 C CE1 . PHE B 1 65 ? 11.640 3.235 39.483 1.00 33.97 ? 85 PHE B CE1 1 ATOM 6269 C CE2 . PHE B 1 65 ? 9.478 2.268 39.101 1.00 33.63 ? 85 PHE B CE2 1 ATOM 6270 C CZ . PHE B 1 65 ? 10.290 3.385 39.176 1.00 33.64 ? 85 PHE B CZ 1 ATOM 6271 N N . LEU B 1 66 ? 10.547 -0.898 42.656 1.00 32.42 ? 86 LEU B N 1 ATOM 6272 C CA . LEU B 1 66 ? 9.522 -0.430 43.587 1.00 32.39 ? 86 LEU B CA 1 ATOM 6273 C C . LEU B 1 66 ? 9.954 -0.570 45.042 1.00 32.54 ? 86 LEU B C 1 ATOM 6274 O O . LEU B 1 66 ? 9.750 0.338 45.844 1.00 32.19 ? 86 LEU B O 1 ATOM 6275 C CB . LEU B 1 66 ? 8.215 -1.209 43.375 1.00 32.35 ? 86 LEU B CB 1 ATOM 6276 C CG . LEU B 1 66 ? 7.499 -0.990 42.038 1.00 31.92 ? 86 LEU B CG 1 ATOM 6277 C CD1 . LEU B 1 66 ? 6.421 -2.036 41.849 1.00 32.39 ? 86 LEU B CD1 1 ATOM 6278 C CD2 . LEU B 1 66 ? 6.912 0.421 41.955 1.00 31.53 ? 86 LEU B CD2 1 ATOM 6279 N N . ASP B 1 67 ? 10.536 -1.715 45.374 1.00 32.97 ? 87 ASP B N 1 ATOM 6280 C CA . ASP B 1 67 ? 10.771 -2.090 46.759 1.00 33.56 ? 87 ASP B CA 1 ATOM 6281 C C . ASP B 1 67 ? 12.210 -1.892 47.224 1.00 34.60 ? 87 ASP B C 1 ATOM 6282 O O . ASP B 1 67 ? 12.435 -1.709 48.415 1.00 34.96 ? 87 ASP B O 1 ATOM 6283 C CB . ASP B 1 67 ? 10.388 -3.553 46.976 1.00 33.30 ? 87 ASP B CB 1 ATOM 6284 C CG . ASP B 1 67 ? 8.919 -3.834 46.677 1.00 32.73 ? 87 ASP B CG 1 ATOM 6285 O OD1 . ASP B 1 67 ? 8.137 -2.885 46.463 1.00 31.02 ? 87 ASP B OD1 1 ATOM 6286 O OD2 . ASP B 1 67 ? 8.542 -5.020 46.670 1.00 31.37 ? 87 ASP B OD2 1 ATOM 6287 N N . LYS B 1 68 ? 13.178 -1.936 46.309 1.00 35.56 ? 88 LYS B N 1 ATOM 6288 C CA . LYS B 1 68 ? 14.599 -1.921 46.700 1.00 36.25 ? 88 LYS B CA 1 ATOM 6289 C C . LYS B 1 68 ? 15.372 -0.752 46.095 1.00 36.93 ? 88 LYS B C 1 ATOM 6290 O O . LYS B 1 68 ? 16.600 -0.790 46.016 1.00 37.16 ? 88 LYS B O 1 ATOM 6291 C CB . LYS B 1 68 ? 15.266 -3.246 46.319 1.00 36.37 ? 88 LYS B CB 1 ATOM 6292 C CG . LYS B 1 68 ? 14.737 -4.439 47.089 1.00 36.32 ? 88 LYS B CG 1 ATOM 6293 C CD . LYS B 1 68 ? 15.075 -5.741 46.385 1.00 37.56 ? 88 LYS B CD 1 ATOM 6294 N N . GLY B 1 69 ? 14.645 0.280 45.672 1.00 37.53 ? 89 GLY B N 1 ATOM 6295 C CA . GLY B 1 69 ? 15.246 1.513 45.179 1.00 38.07 ? 89 GLY B CA 1 ATOM 6296 C C . GLY B 1 69 ? 16.195 1.385 43.999 1.00 38.44 ? 89 GLY B C 1 ATOM 6297 O O . GLY B 1 69 ? 17.108 2.182 43.872 1.00 38.59 ? 89 GLY B O 1 ATOM 6298 N N . GLU B 1 70 ? 15.977 0.396 43.134 1.00 39.02 ? 90 GLU B N 1 ATOM 6299 C CA . GLU B 1 70 ? 16.853 0.165 41.973 1.00 39.26 ? 90 GLU B CA 1 ATOM 6300 C C . GLU B 1 70 ? 16.357 0.926 40.743 1.00 38.95 ? 90 GLU B C 1 ATOM 6301 O O . GLU B 1 70 ? 15.373 1.663 40.818 1.00 38.83 ? 90 GLU B O 1 ATOM 6302 C CB . GLU B 1 70 ? 16.957 -1.330 41.662 1.00 39.48 ? 90 GLU B CB 1 ATOM 6303 C CG . GLU B 1 70 ? 17.334 -2.158 42.868 1.00 41.35 ? 90 GLU B CG 1 ATOM 6304 C CD . GLU B 1 70 ? 18.408 -3.165 42.568 1.00 43.76 ? 90 GLU B CD 1 ATOM 6305 O OE1 . GLU B 1 70 ? 18.116 -4.189 41.899 1.00 46.77 ? 90 GLU B OE1 1 ATOM 6306 O OE2 . GLU B 1 70 ? 19.551 -2.920 43.010 1.00 44.98 ? 90 GLU B OE2 1 ATOM 6307 N N . ARG B 1 71 ? 17.050 0.750 39.619 1.00 38.52 ? 91 ARG B N 1 ATOM 6308 C CA . ARG B 1 71 ? 16.752 1.492 38.397 1.00 38.28 ? 91 ARG B CA 1 ATOM 6309 C C . ARG B 1 71 ? 15.339 1.205 37.875 1.00 38.05 ? 91 ARG B C 1 ATOM 6310 O O . ARG B 1 71 ? 14.828 0.091 38.014 1.00 37.98 ? 91 ARG B O 1 ATOM 6311 C CB . ARG B 1 71 ? 17.772 1.149 37.310 1.00 38.11 ? 91 ARG B CB 1 ATOM 6312 N N . HIS B 1 72 ? 14.721 2.225 37.291 1.00 37.58 ? 92 HIS B N 1 ATOM 6313 C CA . HIS B 1 72 ? 13.485 2.065 36.543 1.00 37.68 ? 92 HIS B CA 1 ATOM 6314 C C . HIS B 1 72 ? 13.759 1.053 35.437 1.00 36.94 ? 92 HIS B C 1 ATOM 6315 O O . HIS B 1 72 ? 14.758 1.176 34.729 1.00 36.87 ? 92 HIS B O 1 ATOM 6316 C CB . HIS B 1 72 ? 13.057 3.405 35.938 1.00 37.87 ? 92 HIS B CB 1 ATOM 6317 C CG . HIS B 1 72 ? 11.636 3.441 35.470 1.00 39.73 ? 92 HIS B CG 1 ATOM 6318 N ND1 . HIS B 1 72 ? 11.117 2.527 34.574 1.00 41.49 ? 92 HIS B ND1 1 ATOM 6319 C CD2 . HIS B 1 72 ? 10.630 4.305 35.749 1.00 41.28 ? 92 HIS B CD2 1 ATOM 6320 C CE1 . HIS B 1 72 ? 9.851 2.822 34.332 1.00 41.73 ? 92 HIS B CE1 1 ATOM 6321 N NE2 . HIS B 1 72 ? 9.529 3.892 35.036 1.00 41.80 ? 92 HIS B NE2 1 ATOM 6322 N N . PRO B 1 73 ? 12.900 0.026 35.300 1.00 36.18 ? 93 PRO B N 1 ATOM 6323 C CA . PRO B 1 73 ? 13.109 -0.932 34.210 1.00 35.61 ? 93 PRO B CA 1 ATOM 6324 C C . PRO B 1 73 ? 12.996 -0.278 32.834 1.00 34.98 ? 93 PRO B C 1 ATOM 6325 O O . PRO B 1 73 ? 12.451 0.825 32.718 1.00 34.59 ? 93 PRO B O 1 ATOM 6326 C CB . PRO B 1 73 ? 11.991 -1.959 34.408 1.00 35.64 ? 93 PRO B CB 1 ATOM 6327 C CG . PRO B 1 73 ? 11.516 -1.775 35.789 1.00 36.09 ? 93 PRO B CG 1 ATOM 6328 C CD . PRO B 1 73 ? 11.764 -0.351 36.158 1.00 36.28 ? 93 PRO B CD 1 ATOM 6329 N N . VAL B 1 74 ? 13.519 -0.950 31.811 1.00 34.44 ? 94 VAL B N 1 ATOM 6330 C CA . VAL B 1 74 ? 13.410 -0.460 30.435 1.00 33.97 ? 94 VAL B CA 1 ATOM 6331 C C . VAL B 1 74 ? 11.952 -0.517 29.987 1.00 33.34 ? 94 VAL B C 1 ATOM 6332 O O . VAL B 1 74 ? 11.293 -1.538 30.132 1.00 33.50 ? 94 VAL B O 1 ATOM 6333 C CB . VAL B 1 74 ? 14.265 -1.285 29.461 1.00 34.07 ? 94 VAL B CB 1 ATOM 6334 C CG1 . VAL B 1 74 ? 14.004 -0.852 28.014 1.00 34.28 ? 94 VAL B CG1 1 ATOM 6335 C CG2 . VAL B 1 74 ? 15.747 -1.142 29.804 1.00 34.25 ? 94 VAL B CG2 1 ATOM 6336 N N . ARG B 1 75 ? 11.452 0.593 29.460 1.00 32.50 ? 95 ARG B N 1 ATOM 6337 C CA . ARG B 1 75 ? 10.099 0.647 28.935 1.00 31.67 ? 95 ARG B CA 1 ATOM 6338 C C . ARG B 1 75 ? 10.092 0.191 27.477 1.00 31.23 ? 95 ARG B C 1 ATOM 6339 O O . ARG B 1 75 ? 10.921 0.643 26.676 1.00 31.05 ? 95 ARG B O 1 ATOM 6340 C CB . ARG B 1 75 ? 9.558 2.062 29.055 1.00 31.54 ? 95 ARG B CB 1 ATOM 6341 C CG . ARG B 1 75 ? 8.065 2.205 28.765 1.00 31.22 ? 95 ARG B CG 1 ATOM 6342 C CD . ARG B 1 75 ? 7.615 3.552 29.262 1.00 30.95 ? 95 ARG B CD 1 ATOM 6343 N NE . ARG B 1 75 ? 6.252 3.932 28.898 1.00 31.28 ? 95 ARG B NE 1 ATOM 6344 C CZ . ARG B 1 75 ? 5.141 3.446 29.449 1.00 30.36 ? 95 ARG B CZ 1 ATOM 6345 N NH1 . ARG B 1 75 ? 5.189 2.483 30.370 1.00 28.98 ? 95 ARG B NH1 1 ATOM 6346 N NH2 . ARG B 1 75 ? 3.963 3.911 29.043 1.00 30.64 ? 95 ARG B NH2 1 ATOM 6347 N N . GLU B 1 76 ? 9.166 -0.711 27.145 1.00 30.38 ? 96 GLU B N 1 ATOM 6348 C CA . GLU B 1 76 ? 9.040 -1.245 25.784 1.00 30.04 ? 96 GLU B CA 1 ATOM 6349 C C . GLU B 1 76 ? 7.600 -1.334 25.316 1.00 29.31 ? 96 GLU B C 1 ATOM 6350 O O . GLU B 1 76 ? 6.658 -1.329 26.123 1.00 29.33 ? 96 GLU B O 1 ATOM 6351 C CB . GLU B 1 76 ? 9.602 -2.658 25.712 1.00 30.38 ? 96 GLU B CB 1 ATOM 6352 C CG . GLU B 1 76 ? 11.046 -2.794 26.058 1.00 31.06 ? 96 GLU B CG 1 ATOM 6353 C CD . GLU B 1 76 ? 11.498 -4.231 25.973 1.00 32.89 ? 96 GLU B CD 1 ATOM 6354 O OE1 . GLU B 1 76 ? 10.791 -5.112 26.522 1.00 32.58 ? 96 GLU B OE1 1 ATOM 6355 O OE2 . GLU B 1 76 ? 12.555 -4.478 25.349 1.00 33.42 ? 96 GLU B OE2 1 ATOM 6356 N N . ALA B 1 77 ? 7.448 -1.466 24.003 1.00 28.26 ? 97 ALA B N 1 ATOM 6357 C CA . ALA B 1 77 ? 6.154 -1.722 23.380 1.00 27.48 ? 97 ALA B CA 1 ATOM 6358 C C . ALA B 1 77 ? 6.136 -3.118 22.782 1.00 26.92 ? 97 ALA B C 1 ATOM 6359 O O . ALA B 1 77 ? 7.168 -3.640 22.353 1.00 26.33 ? 97 ALA B O 1 ATOM 6360 C CB . ALA B 1 77 ? 5.861 -0.674 22.303 1.00 27.00 ? 97 ALA B CB 1 ATOM 6361 N N . ARG B 1 78 ? 4.954 -3.725 22.800 1.00 26.65 ? 98 ARG B N 1 ATOM 6362 C CA . ARG B 1 78 ? 4.660 -4.938 22.042 1.00 26.11 ? 98 ARG B CA 1 ATOM 6363 C C . ARG B 1 78 ? 4.089 -4.471 20.715 1.00 25.83 ? 98 ARG B C 1 ATOM 6364 O O . ARG B 1 78 ? 3.168 -3.659 20.698 1.00 25.50 ? 98 ARG B O 1 ATOM 6365 C CB . ARG B 1 78 ? 3.622 -5.785 22.778 1.00 26.14 ? 98 ARG B CB 1 ATOM 6366 C CG . ARG B 1 78 ? 3.083 -6.989 22.008 1.00 25.74 ? 98 ARG B CG 1 ATOM 6367 C CD . ARG B 1 78 ? 1.756 -7.444 22.574 1.00 25.57 ? 98 ARG B CD 1 ATOM 6368 N NE . ARG B 1 78 ? 1.168 -8.550 21.828 1.00 26.09 ? 98 ARG B NE 1 ATOM 6369 C CZ . ARG B 1 78 ? -0.058 -9.042 22.033 1.00 27.22 ? 98 ARG B CZ 1 ATOM 6370 N NH1 . ARG B 1 78 ? -0.860 -8.533 22.975 1.00 26.05 ? 98 ARG B NH1 1 ATOM 6371 N NH2 . ARG B 1 78 ? -0.490 -10.056 21.288 1.00 27.25 ? 98 ARG B NH2 1 ATOM 6372 N N . ALA B 1 79 ? 4.642 -4.973 19.613 1.00 25.26 ? 99 ALA B N 1 ATOM 6373 C CA . ALA B 1 79 ? 4.180 -4.613 18.283 1.00 24.71 ? 99 ALA B CA 1 ATOM 6374 C C . ALA B 1 79 ? 3.882 -5.881 17.517 1.00 24.36 ? 99 ALA B C 1 ATOM 6375 O O . ALA B 1 79 ? 4.761 -6.721 17.337 1.00 24.45 ? 99 ALA B O 1 ATOM 6376 C CB . ALA B 1 79 ? 5.230 -3.790 17.557 1.00 25.00 ? 99 ALA B CB 1 ATOM 6377 N N . VAL B 1 80 ? 2.634 -6.017 17.075 1.00 23.80 ? 100 VAL B N 1 ATOM 6378 C CA . VAL B 1 80 ? 2.199 -7.181 16.319 1.00 23.02 ? 100 VAL B CA 1 ATOM 6379 C C . VAL B 1 80 ? 2.169 -6.805 14.840 1.00 23.21 ? 100 VAL B C 1 ATOM 6380 O O . VAL B 1 80 ? 1.452 -5.870 14.444 1.00 23.11 ? 100 VAL B O 1 ATOM 6381 C CB . VAL B 1 80 ? 0.800 -7.627 16.761 1.00 22.82 ? 100 VAL B CB 1 ATOM 6382 C CG1 . VAL B 1 80 ? 0.355 -8.861 15.970 1.00 21.26 ? 100 VAL B CG1 1 ATOM 6383 C CG2 . VAL B 1 80 ? 0.783 -7.887 18.266 1.00 21.72 ? 100 VAL B CG2 1 ATOM 6384 N N . ILE B 1 81 ? 2.955 -7.512 14.030 1.00 23.17 ? 101 ILE B N 1 ATOM 6385 C CA . ILE B 1 81 ? 3.053 -7.194 12.601 1.00 23.11 ? 101 ILE B CA 1 ATOM 6386 C C . ILE B 1 81 ? 2.490 -8.335 11.795 1.00 23.32 ? 101 ILE B C 1 ATOM 6387 O O . ILE B 1 81 ? 2.899 -9.484 11.972 1.00 23.49 ? 101 ILE B O 1 ATOM 6388 C CB . ILE B 1 81 ? 4.496 -6.916 12.147 1.00 23.42 ? 101 ILE B CB 1 ATOM 6389 C CG1 . ILE B 1 81 ? 5.084 -5.743 12.939 1.00 23.87 ? 101 ILE B CG1 1 ATOM 6390 C CG2 . ILE B 1 81 ? 4.528 -6.594 10.650 1.00 22.08 ? 101 ILE B CG2 1 ATOM 6391 C CD1 . ILE B 1 81 ? 6.499 -5.345 12.506 1.00 24.66 ? 101 ILE B CD1 1 ATOM 6392 N N . PHE B 1 82 ? 1.519 -8.011 10.942 1.00 23.32 ? 102 PHE B N 1 ATOM 6393 C CA . PHE B 1 82 ? 0.959 -8.943 9.978 1.00 23.43 ? 102 PHE B CA 1 ATOM 6394 C C . PHE B 1 82 ? 1.880 -8.858 8.772 1.00 23.90 ? 102 PHE B C 1 ATOM 6395 O O . PHE B 1 82 ? 1.924 -7.816 8.125 1.00 23.25 ? 102 PHE B O 1 ATOM 6396 C CB . PHE B 1 82 ? -0.453 -8.495 9.545 1.00 23.22 ? 102 PHE B CB 1 ATOM 6397 C CG . PHE B 1 82 ? -1.563 -8.781 10.547 1.00 23.56 ? 102 PHE B CG 1 ATOM 6398 C CD1 . PHE B 1 82 ? -1.311 -9.258 11.827 1.00 22.79 ? 102 PHE B CD1 1 ATOM 6399 C CD2 . PHE B 1 82 ? -2.884 -8.533 10.188 1.00 22.97 ? 102 PHE B CD2 1 ATOM 6400 C CE1 . PHE B 1 82 ? -2.354 -9.501 12.705 1.00 23.45 ? 102 PHE B CE1 1 ATOM 6401 C CE2 . PHE B 1 82 ? -3.933 -8.774 11.075 1.00 22.89 ? 102 PHE B CE2 1 ATOM 6402 C CZ . PHE B 1 82 ? -3.675 -9.261 12.321 1.00 21.96 ? 102 PHE B CZ 1 ATOM 6403 N N . PHE B 1 83 ? 2.610 -9.937 8.477 1.00 24.69 ? 103 PHE B N 1 ATOM 6404 C CA . PHE B 1 83 ? 3.446 -10.015 7.267 1.00 25.19 ? 103 PHE B CA 1 ATOM 6405 C C . PHE B 1 83 ? 2.708 -10.751 6.147 1.00 25.75 ? 103 PHE B C 1 ATOM 6406 O O . PHE B 1 83 ? 2.923 -11.948 5.913 1.00 26.34 ? 103 PHE B O 1 ATOM 6407 C CB . PHE B 1 83 ? 4.773 -10.721 7.551 1.00 25.06 ? 103 PHE B CB 1 ATOM 6408 C CG . PHE B 1 83 ? 5.739 -9.904 8.364 1.00 26.16 ? 103 PHE B CG 1 ATOM 6409 C CD1 . PHE B 1 83 ? 6.052 -10.263 9.665 1.00 27.59 ? 103 PHE B CD1 1 ATOM 6410 C CD2 . PHE B 1 83 ? 6.330 -8.775 7.829 1.00 27.46 ? 103 PHE B CD2 1 ATOM 6411 C CE1 . PHE B 1 83 ? 6.946 -9.512 10.412 1.00 28.58 ? 103 PHE B CE1 1 ATOM 6412 C CE2 . PHE B 1 83 ? 7.225 -8.015 8.571 1.00 28.45 ? 103 PHE B CE2 1 ATOM 6413 C CZ . PHE B 1 83 ? 7.533 -8.386 9.865 1.00 28.45 ? 103 PHE B CZ 1 ATOM 6414 N N . GLY B 1 84 ? 1.843 -10.030 5.444 1.00 26.19 ? 104 GLY B N 1 ATOM 6415 C CA . GLY B 1 84 ? 1.062 -10.607 4.358 1.00 26.53 ? 104 GLY B CA 1 ATOM 6416 C C . GLY B 1 84 ? 1.700 -10.462 2.989 1.00 26.99 ? 104 GLY B C 1 ATOM 6417 O O . GLY B 1 84 ? 1.273 -11.117 2.047 1.00 26.51 ? 104 GLY B O 1 ATOM 6418 N N . ASP B 1 85 ? 2.709 -9.593 2.881 1.00 27.53 ? 105 ASP B N 1 ATOM 6419 C CA . ASP B 1 85 ? 3.375 -9.298 1.603 1.00 27.91 ? 105 ASP B CA 1 ATOM 6420 C C . ASP B 1 85 ? 4.634 -10.155 1.468 1.00 27.91 ? 105 ASP B C 1 ATOM 6421 O O . ASP B 1 85 ? 5.751 -9.648 1.417 1.00 27.92 ? 105 ASP B O 1 ATOM 6422 C CB . ASP B 1 85 ? 3.723 -7.801 1.547 1.00 28.42 ? 105 ASP B CB 1 ATOM 6423 C CG . ASP B 1 85 ? 4.201 -7.346 0.180 1.00 29.30 ? 105 ASP B CG 1 ATOM 6424 O OD1 . ASP B 1 85 ? 4.052 -8.090 -0.804 1.00 30.40 ? 105 ASP B OD1 1 ATOM 6425 O OD2 . ASP B 1 85 ? 4.729 -6.219 0.098 1.00 31.27 ? 105 ASP B OD2 1 ATOM 6426 N N . GLN B 1 86 ? 4.435 -11.465 1.445 1.00 27.98 ? 106 GLN B N 1 ATOM 6427 C CA . GLN B 1 86 ? 5.518 -12.427 1.262 1.00 28.18 ? 106 GLN B CA 1 ATOM 6428 C C . GLN B 1 86 ? 4.890 -13.752 0.869 1.00 28.30 ? 106 GLN B C 1 ATOM 6429 O O . GLN B 1 86 ? 3.680 -13.928 1.031 1.00 28.52 ? 106 GLN B O 1 ATOM 6430 C CB . GLN B 1 86 ? 6.365 -12.570 2.531 1.00 28.18 ? 106 GLN B CB 1 ATOM 6431 C CG . GLN B 1 86 ? 5.574 -12.934 3.784 1.00 28.22 ? 106 GLN B CG 1 ATOM 6432 C CD . GLN B 1 86 ? 6.369 -12.766 5.064 1.00 27.23 ? 106 GLN B CD 1 ATOM 6433 O OE1 . GLN B 1 86 ? 6.961 -11.714 5.307 1.00 28.14 ? 106 GLN B OE1 1 ATOM 6434 N NE2 . GLN B 1 86 ? 6.370 -13.798 5.905 1.00 26.14 ? 106 GLN B NE2 1 ATOM 6435 N N . GLU B 1 87 ? 5.704 -14.661 0.331 1.00 28.10 ? 107 GLU B N 1 ATOM 6436 C CA . GLU B 1 87 ? 5.224 -15.949 -0.169 1.00 27.88 ? 107 GLU B CA 1 ATOM 6437 C C . GLU B 1 87 ? 4.498 -16.752 0.899 1.00 27.43 ? 107 GLU B C 1 ATOM 6438 O O . GLU B 1 87 ? 3.476 -17.388 0.625 1.00 27.51 ? 107 GLU B O 1 ATOM 6439 C CB . GLU B 1 87 ? 6.398 -16.785 -0.705 1.00 28.08 ? 107 GLU B CB 1 ATOM 6440 N N . HIS B 1 88 ? 5.049 -16.735 2.107 1.00 27.15 ? 108 HIS B N 1 ATOM 6441 C CA . HIS B 1 88 ? 4.505 -17.488 3.223 1.00 27.24 ? 108 HIS B CA 1 ATOM 6442 C C . HIS B 1 88 ? 4.117 -16.502 4.334 1.00 26.59 ? 108 HIS B C 1 ATOM 6443 O O . HIS B 1 88 ? 4.910 -16.219 5.239 1.00 25.97 ? 108 HIS B O 1 ATOM 6444 C CB . HIS B 1 88 ? 5.523 -18.524 3.690 1.00 27.60 ? 108 HIS B CB 1 ATOM 6445 C CG . HIS B 1 88 ? 5.884 -19.525 2.636 1.00 28.88 ? 108 HIS B CG 1 ATOM 6446 N ND1 . HIS B 1 88 ? 4.978 -20.427 2.125 1.00 31.15 ? 108 HIS B ND1 1 ATOM 6447 C CD2 . HIS B 1 88 ? 7.055 -19.766 1.998 1.00 31.16 ? 108 HIS B CD2 1 ATOM 6448 C CE1 . HIS B 1 88 ? 5.572 -21.175 1.212 1.00 31.95 ? 108 HIS B CE1 1 ATOM 6449 N NE2 . HIS B 1 88 ? 6.835 -20.799 1.121 1.00 31.05 ? 108 HIS B NE2 1 ATOM 6450 N N . PRO B 1 89 ? 2.900 -15.940 4.236 1.00 25.93 ? 109 PRO B N 1 ATOM 6451 C CA . PRO B 1 89 ? 2.450 -14.941 5.201 1.00 25.90 ? 109 PRO B CA 1 ATOM 6452 C C . PRO B 1 89 ? 2.504 -15.431 6.633 1.00 25.28 ? 109 PRO B C 1 ATOM 6453 O O . PRO B 1 89 ? 2.269 -16.610 6.881 1.00 25.23 ? 109 PRO B O 1 ATOM 6454 C CB . PRO B 1 89 ? 0.995 -14.706 4.796 1.00 25.68 ? 109 PRO B CB 1 ATOM 6455 C CG . PRO B 1 89 ? 0.978 -14.998 3.348 1.00 26.20 ? 109 PRO B CG 1 ATOM 6456 C CD . PRO B 1 89 ? 1.904 -16.144 3.169 1.00 25.72 ? 109 PRO B CD 1 ATOM 6457 N N . ASN B 1 90 ? 2.821 -14.536 7.562 1.00 25.01 ? 110 ASN B N 1 ATOM 6458 C CA . ASN B 1 90 ? 2.718 -14.865 8.976 1.00 24.88 ? 110 ASN B CA 1 ATOM 6459 C C . ASN B 1 90 ? 2.470 -13.647 9.843 1.00 24.25 ? 110 ASN B C 1 ATOM 6460 O O . ASN B 1 90 ? 2.473 -12.518 9.351 1.00 24.53 ? 110 ASN B O 1 ATOM 6461 C CB . ASN B 1 90 ? 3.944 -15.667 9.442 1.00 25.02 ? 110 ASN B CB 1 ATOM 6462 C CG . ASN B 1 90 ? 5.169 -14.806 9.712 1.00 26.39 ? 110 ASN B CG 1 ATOM 6463 O OD1 . ASN B 1 90 ? 5.089 -13.784 10.396 1.00 26.59 ? 110 ASN B OD1 1 ATOM 6464 N ND2 . ASN B 1 90 ? 6.327 -15.238 9.187 1.00 28.07 ? 110 ASN B ND2 1 ATOM 6465 N N . VAL B 1 91 ? 2.200 -13.887 11.121 1.00 23.46 ? 111 VAL B N 1 ATOM 6466 C CA . VAL B 1 91 ? 2.190 -12.832 12.117 1.00 23.13 ? 111 VAL B CA 1 ATOM 6467 C C . VAL B 1 91 ? 3.435 -13.031 12.973 1.00 23.14 ? 111 VAL B C 1 ATOM 6468 O O . VAL B 1 91 ? 3.695 -14.141 13.405 1.00 22.88 ? 111 VAL B O 1 ATOM 6469 C CB . VAL B 1 91 ? 0.948 -12.897 13.033 1.00 22.86 ? 111 VAL B CB 1 ATOM 6470 C CG1 . VAL B 1 91 ? 0.955 -11.732 14.009 1.00 22.69 ? 111 VAL B CG1 1 ATOM 6471 C CG2 . VAL B 1 91 ? -0.341 -12.897 12.222 1.00 22.99 ? 111 VAL B CG2 1 ATOM 6472 N N . THR B 1 92 ? 4.200 -11.968 13.199 1.00 23.31 ? 112 THR B N 1 ATOM 6473 C CA . THR B 1 92 ? 5.309 -11.997 14.164 1.00 23.72 ? 112 THR B CA 1 ATOM 6474 C C . THR B 1 92 ? 5.189 -10.824 15.125 1.00 24.11 ? 112 THR B C 1 ATOM 6475 O O . THR B 1 92 ? 4.839 -9.712 14.735 1.00 23.88 ? 112 THR B O 1 ATOM 6476 C CB . THR B 1 92 ? 6.691 -11.947 13.469 1.00 23.78 ? 112 THR B CB 1 ATOM 6477 O OG1 . THR B 1 92 ? 6.766 -12.976 12.479 1.00 23.95 ? 112 THR B OG1 1 ATOM 6478 C CG2 . THR B 1 92 ? 7.822 -12.119 14.474 1.00 22.63 ? 112 THR B CG2 1 ATOM 6479 N N . GLU B 1 93 ? 5.468 -11.087 16.392 1.00 24.95 ? 113 GLU B N 1 ATOM 6480 C CA . GLU B 1 93 ? 5.426 -10.055 17.412 1.00 26.07 ? 113 GLU B CA 1 ATOM 6481 C C . GLU B 1 93 ? 6.833 -9.638 17.776 1.00 26.71 ? 113 GLU B C 1 ATOM 6482 O O . GLU B 1 93 ? 7.747 -10.469 17.796 1.00 26.27 ? 113 GLU B O 1 ATOM 6483 C CB . GLU B 1 93 ? 4.750 -10.575 18.667 1.00 26.19 ? 113 GLU B CB 1 ATOM 6484 C CG . GLU B 1 93 ? 3.382 -11.129 18.426 1.00 26.41 ? 113 GLU B CG 1 ATOM 6485 C CD . GLU B 1 93 ? 2.478 -10.966 19.621 1.00 28.02 ? 113 GLU B CD 1 ATOM 6486 O OE1 . GLU B 1 93 ? 2.889 -10.338 20.620 1.00 27.97 ? 113 GLU B OE1 1 ATOM 6487 O OE2 . GLU B 1 93 ? 1.343 -11.464 19.561 1.00 29.77 ? 113 GLU B OE2 1 ATOM 6488 N N . PHE B 1 94 ? 6.987 -8.356 18.094 1.00 27.44 ? 114 PHE B N 1 ATOM 6489 C CA . PHE B 1 94 ? 8.272 -7.813 18.488 1.00 27.93 ? 114 PHE B CA 1 ATOM 6490 C C . PHE B 1 94 ? 8.185 -6.998 19.769 1.00 28.31 ? 114 PHE B C 1 ATOM 6491 O O . PHE B 1 94 ? 7.158 -6.394 20.073 1.00 28.39 ? 114 PHE B O 1 ATOM 6492 C CB . PHE B 1 94 ? 8.811 -6.918 17.376 1.00 28.43 ? 114 PHE B CB 1 ATOM 6493 C CG . PHE B 1 94 ? 8.948 -7.614 16.060 1.00 28.57 ? 114 PHE B CG 1 ATOM 6494 C CD1 . PHE B 1 94 ? 7.861 -7.717 15.203 1.00 30.03 ? 114 PHE B CD1 1 ATOM 6495 C CD2 . PHE B 1 94 ? 10.160 -8.166 15.680 1.00 29.59 ? 114 PHE B CD2 1 ATOM 6496 C CE1 . PHE B 1 94 ? 7.979 -8.369 13.975 1.00 30.63 ? 114 PHE B CE1 1 ATOM 6497 C CE2 . PHE B 1 94 ? 10.297 -8.816 14.450 1.00 30.47 ? 114 PHE B CE2 1 ATOM 6498 C CZ . PHE B 1 94 ? 9.199 -8.920 13.598 1.00 30.67 ? 114 PHE B CZ 1 ATOM 6499 N N . ALA B 1 95 ? 9.282 -6.986 20.512 1.00 28.63 ? 115 ALA B N 1 ATOM 6500 C CA . ALA B 1 95 ? 9.479 -6.032 21.583 1.00 29.11 ? 115 ALA B CA 1 ATOM 6501 C C . ALA B 1 95 ? 10.220 -4.848 20.956 1.00 29.50 ? 115 ALA B C 1 ATOM 6502 O O . ALA B 1 95 ? 11.312 -5.023 20.408 1.00 29.79 ? 115 ALA B O 1 ATOM 6503 C CB . ALA B 1 95 ? 10.296 -6.659 22.711 1.00 28.71 ? 115 ALA B CB 1 ATOM 6504 N N . VAL B 1 96 ? 9.610 -3.666 20.997 1.00 29.86 ? 116 VAL B N 1 ATOM 6505 C CA . VAL B 1 96 ? 10.222 -2.458 20.466 1.00 29.98 ? 116 VAL B CA 1 ATOM 6506 C C . VAL B 1 96 ? 10.592 -1.550 21.630 1.00 30.96 ? 116 VAL B C 1 ATOM 6507 O O . VAL B 1 96 ? 9.765 -1.278 22.515 1.00 30.56 ? 116 VAL B O 1 ATOM 6508 C CB . VAL B 1 96 ? 9.285 -1.715 19.489 1.00 30.11 ? 116 VAL B CB 1 ATOM 6509 C CG1 . VAL B 1 96 ? 9.958 -0.459 18.943 1.00 28.59 ? 116 VAL B CG1 1 ATOM 6510 C CG2 . VAL B 1 96 ? 8.871 -2.640 18.342 1.00 29.06 ? 116 VAL B CG2 1 ATOM 6511 N N . GLY B 1 97 ? 11.840 -1.091 21.632 1.00 31.74 ? 117 GLY B N 1 ATOM 6512 C CA . GLY B 1 97 ? 12.357 -0.279 22.733 1.00 32.40 ? 117 GLY B CA 1 ATOM 6513 C C . GLY B 1 97 ? 13.704 0.350 22.407 1.00 32.91 ? 117 GLY B C 1 ATOM 6514 O O . GLY B 1 97 ? 14.246 0.118 21.331 1.00 33.04 ? 117 GLY B O 1 ATOM 6515 N N . PRO B 1 98 ? 14.250 1.160 23.332 1.00 33.36 ? 118 PRO B N 1 ATOM 6516 C CA . PRO B 1 98 ? 13.603 1.555 24.580 1.00 33.47 ? 118 PRO B CA 1 ATOM 6517 C C . PRO B 1 98 ? 12.685 2.731 24.346 1.00 33.26 ? 118 PRO B C 1 ATOM 6518 O O . PRO B 1 98 ? 12.612 3.244 23.233 1.00 33.47 ? 118 PRO B O 1 ATOM 6519 C CB . PRO B 1 98 ? 14.782 1.957 25.474 1.00 33.59 ? 118 PRO B CB 1 ATOM 6520 C CG . PRO B 1 98 ? 15.805 2.479 24.503 1.00 34.00 ? 118 PRO B CG 1 ATOM 6521 C CD . PRO B 1 98 ? 15.626 1.688 23.230 1.00 33.45 ? 118 PRO B CD 1 ATOM 6522 N N . LEU B 1 99 ? 11.975 3.144 25.387 1.00 33.42 ? 119 LEU B N 1 ATOM 6523 C CA . LEU B 1 99 ? 11.114 4.312 25.316 1.00 33.52 ? 119 LEU B CA 1 ATOM 6524 C C . LEU B 1 99 ? 11.499 5.244 26.453 1.00 33.75 ? 119 LEU B C 1 ATOM 6525 O O . LEU B 1 99 ? 11.648 4.796 27.591 1.00 33.87 ? 119 LEU B O 1 ATOM 6526 C CB . LEU B 1 99 ? 9.639 3.909 25.427 1.00 33.57 ? 119 LEU B CB 1 ATOM 6527 C CG . LEU B 1 99 ? 9.073 3.083 24.263 1.00 33.92 ? 119 LEU B CG 1 ATOM 6528 C CD1 . LEU B 1 99 ? 7.695 2.485 24.606 1.00 32.98 ? 119 LEU B CD1 1 ATOM 6529 C CD2 . LEU B 1 99 ? 8.987 3.922 22.994 1.00 33.34 ? 119 LEU B CD2 1 ATOM 6530 N N . PRO B 1 100 ? 11.694 6.538 26.159 1.00 34.20 ? 120 PRO B N 1 ATOM 6531 C CA . PRO B 1 100 ? 11.666 7.160 24.835 1.00 34.56 ? 120 PRO B CA 1 ATOM 6532 C C . PRO B 1 100 ? 12.891 6.804 23.977 1.00 34.92 ? 120 PRO B C 1 ATOM 6533 O O . PRO B 1 100 ? 13.886 6.284 24.492 1.00 34.63 ? 120 PRO B O 1 ATOM 6534 C CB . PRO B 1 100 ? 11.634 8.654 25.152 1.00 34.32 ? 120 PRO B CB 1 ATOM 6535 C CG . PRO B 1 100 ? 12.284 8.774 26.477 1.00 34.52 ? 120 PRO B CG 1 ATOM 6536 C CD . PRO B 1 100 ? 11.979 7.516 27.224 1.00 34.08 ? 120 PRO B CD 1 ATOM 6537 N N . GLY B 1 101 ? 12.781 7.055 22.671 1.00 35.44 ? 121 GLY B N 1 ATOM 6538 C CA . GLY B 1 101 ? 13.886 6.865 21.726 1.00 35.82 ? 121 GLY B CA 1 ATOM 6539 C C . GLY B 1 101 ? 14.174 5.431 21.317 1.00 36.31 ? 121 GLY B C 1 ATOM 6540 O O . GLY B 1 101 ? 15.276 4.930 21.561 1.00 36.72 ? 121 GLY B O 1 ATOM 6541 N N . PRO B 1 102 ? 13.203 4.759 20.661 1.00 36.61 ? 122 PRO B N 1 ATOM 6542 C CA . PRO B 1 102 ? 13.388 3.347 20.292 1.00 36.92 ? 122 PRO B CA 1 ATOM 6543 C C . PRO B 1 102 ? 14.552 3.103 19.322 1.00 37.50 ? 122 PRO B C 1 ATOM 6544 O O . PRO B 1 102 ? 14.753 3.887 18.398 1.00 37.40 ? 122 PRO B O 1 ATOM 6545 C CB . PRO B 1 102 ? 12.049 2.963 19.638 1.00 36.72 ? 122 PRO B CB 1 ATOM 6546 C CG . PRO B 1 102 ? 11.381 4.240 19.292 1.00 36.61 ? 122 PRO B CG 1 ATOM 6547 C CD . PRO B 1 102 ? 11.903 5.293 20.215 1.00 36.38 ? 122 PRO B CD 1 ATOM 6548 N N A CYS B 1 103 ? 15.303 2.027 19.571 0.70 38.07 ? 123 CYS B N 1 ATOM 6549 N N B CYS B 1 103 ? 15.302 2.025 19.535 0.30 37.60 ? 123 CYS B N 1 ATOM 6550 C CA A CYS B 1 103 ? 16.439 1.608 18.733 0.70 38.68 ? 123 CYS B CA 1 ATOM 6551 C CA B CYS B 1 103 ? 16.388 1.661 18.619 0.30 37.75 ? 123 CYS B CA 1 ATOM 6552 C C A CYS B 1 103 ? 16.265 0.224 18.140 0.70 38.64 ? 123 CYS B C 1 ATOM 6553 C C B CYS B 1 103 ? 16.497 0.163 18.311 0.30 38.07 ? 123 CYS B C 1 ATOM 6554 O O A CYS B 1 103 ? 16.719 -0.033 17.028 0.70 39.06 ? 123 CYS B O 1 ATOM 6555 O O B CYS B 1 103 ? 17.398 -0.235 17.569 0.30 38.13 ? 123 CYS B O 1 ATOM 6556 C CB A CYS B 1 103 ? 17.726 1.550 19.555 0.70 38.77 ? 123 CYS B CB 1 ATOM 6557 C CB B CYS B 1 103 ? 17.731 2.176 19.155 0.30 37.69 ? 123 CYS B CB 1 ATOM 6558 S SG A CYS B 1 103 ? 18.086 3.021 20.445 0.70 40.32 ? 123 CYS B SG 1 ATOM 6559 S SG B CYS B 1 103 ? 18.496 1.129 20.418 0.30 36.86 ? 123 CYS B SG 1 ATOM 6560 N N . TYR B 1 104 ? 15.626 -0.668 18.890 1.00 38.36 ? 124 TYR B N 1 ATOM 6561 C CA . TYR B 1 104 ? 15.588 -2.085 18.544 1.00 38.58 ? 124 TYR B CA 1 ATOM 6562 C C . TYR B 1 104 ? 14.170 -2.625 18.368 1.00 38.75 ? 124 TYR B C 1 ATOM 6563 O O . TYR B 1 104 ? 13.167 -2.000 18.738 1.00 38.98 ? 124 TYR B O 1 ATOM 6564 C CB . TYR B 1 104 ? 16.347 -2.928 19.580 1.00 38.50 ? 124 TYR B CB 1 ATOM 6565 C CG . TYR B 1 104 ? 15.779 -2.866 20.980 1.00 39.02 ? 124 TYR B CG 1 ATOM 6566 C CD1 . TYR B 1 104 ? 14.743 -3.712 21.377 1.00 38.65 ? 124 TYR B CD1 1 ATOM 6567 C CD2 . TYR B 1 104 ? 16.285 -1.970 21.911 1.00 39.59 ? 124 TYR B CD2 1 ATOM 6568 C CE1 . TYR B 1 104 ? 14.225 -3.655 22.663 1.00 38.47 ? 124 TYR B CE1 1 ATOM 6569 C CE2 . TYR B 1 104 ? 15.774 -1.906 23.196 1.00 39.22 ? 124 TYR B CE2 1 ATOM 6570 C CZ . TYR B 1 104 ? 14.748 -2.746 23.568 1.00 38.99 ? 124 TYR B CZ 1 ATOM 6571 O OH . TYR B 1 104 ? 14.257 -2.663 24.853 1.00 39.41 ? 124 TYR B OH 1 ATOM 6572 N N . MET B 1 105 ? 14.137 -3.818 17.800 1.00 38.79 ? 125 MET B N 1 ATOM 6573 C CA . MET B 1 105 ? 12.932 -4.510 17.439 1.00 38.85 ? 125 MET B CA 1 ATOM 6574 C C . MET B 1 105 ? 13.298 -5.984 17.568 1.00 38.38 ? 125 MET B C 1 ATOM 6575 O O . MET B 1 105 ? 14.059 -6.495 16.756 1.00 38.60 ? 125 MET B O 1 ATOM 6576 C CB . MET B 1 105 ? 12.600 -4.120 16.003 1.00 38.85 ? 125 MET B CB 1 ATOM 6577 C CG . MET B 1 105 ? 11.462 -4.849 15.344 1.00 39.80 ? 125 MET B CG 1 ATOM 6578 S SD . MET B 1 105 ? 11.266 -4.228 13.650 1.00 39.00 ? 125 MET B SD 1 ATOM 6579 C CE . MET B 1 105 ? 9.984 -5.346 13.069 1.00 40.01 ? 125 MET B CE 1 ATOM 6580 N N . ARG B 1 106 ? 12.802 -6.651 18.606 1.00 38.05 ? 126 ARG B N 1 ATOM 6581 C CA . ARG B 1 106 ? 13.186 -8.042 18.888 1.00 37.94 ? 126 ARG B CA 1 ATOM 6582 C C . ARG B 1 106 ? 11.987 -8.988 18.807 1.00 38.02 ? 126 ARG B C 1 ATOM 6583 O O . ARG B 1 106 ? 11.006 -8.806 19.518 1.00 37.76 ? 126 ARG B O 1 ATOM 6584 C CB . ARG B 1 106 ? 13.829 -8.145 20.274 1.00 37.74 ? 126 ARG B CB 1 ATOM 6585 N N . ALA B 1 107 ? 12.088 -10.002 17.947 1.00 37.99 ? 127 ALA B N 1 ATOM 6586 C CA . ALA B 1 107 ? 11.026 -10.990 17.757 1.00 38.05 ? 127 ALA B CA 1 ATOM 6587 C C . ALA B 1 107 ? 10.717 -11.759 19.045 1.00 38.05 ? 127 ALA B C 1 ATOM 6588 O O . ALA B 1 107 ? 11.619 -12.087 19.805 1.00 37.98 ? 127 ALA B O 1 ATOM 6589 C CB . ALA B 1 107 ? 11.413 -11.959 16.651 1.00 37.93 ? 127 ALA B CB 1 ATOM 6590 N N . LEU B 1 108 ? 9.438 -12.053 19.266 1.00 38.12 ? 128 LEU B N 1 ATOM 6591 C CA . LEU B 1 108 ? 8.980 -12.701 20.487 1.00 38.07 ? 128 LEU B CA 1 ATOM 6592 C C . LEU B 1 108 ? 8.390 -14.072 20.197 1.00 38.43 ? 128 LEU B C 1 ATOM 6593 O O . LEU B 1 108 ? 7.969 -14.346 19.073 1.00 38.81 ? 128 LEU B O 1 ATOM 6594 C CB . LEU B 1 108 ? 7.915 -11.843 21.163 1.00 37.83 ? 128 LEU B CB 1 ATOM 6595 C CG . LEU B 1 108 ? 8.324 -10.413 21.517 1.00 37.89 ? 128 LEU B CG 1 ATOM 6596 C CD1 . LEU B 1 108 ? 7.161 -9.651 22.158 1.00 37.87 ? 128 LEU B CD1 1 ATOM 6597 C CD2 . LEU B 1 108 ? 9.533 -10.422 22.438 1.00 38.05 ? 128 LEU B CD2 1 ATOM 6598 N N . SER B 1 109 ? 8.395 -14.928 21.219 1.00 38.58 ? 129 SER B N 1 ATOM 6599 C CA . SER B 1 109 ? 7.627 -16.188 21.250 1.00 38.62 ? 129 SER B CA 1 ATOM 6600 C C . SER B 1 109 ? 7.525 -16.983 19.931 1.00 38.34 ? 129 SER B C 1 ATOM 6601 O O . SER B 1 109 ? 6.428 -17.158 19.396 1.00 38.72 ? 129 SER B O 1 ATOM 6602 C CB . SER B 1 109 ? 6.210 -15.905 21.784 1.00 38.60 ? 129 SER B CB 1 ATOM 6603 N N . PRO B 1 110 ? 8.659 -17.498 19.422 1.00 37.65 ? 130 PRO B N 1 ATOM 6604 C CA . PRO B 1 110 ? 8.617 -18.411 18.264 1.00 37.04 ? 130 PRO B CA 1 ATOM 6605 C C . PRO B 1 110 ? 7.876 -19.721 18.559 1.00 36.19 ? 130 PRO B C 1 ATOM 6606 O O . PRO B 1 110 ? 7.879 -20.175 19.698 1.00 36.62 ? 130 PRO B O 1 ATOM 6607 C CB . PRO B 1 110 ? 10.097 -18.697 17.990 1.00 37.31 ? 130 PRO B CB 1 ATOM 6608 C CG . PRO B 1 110 ? 10.814 -18.336 19.271 1.00 37.55 ? 130 PRO B CG 1 ATOM 6609 C CD . PRO B 1 110 ? 10.038 -17.213 19.855 1.00 37.78 ? 130 PRO B CD 1 ATOM 6610 N N . ARG B 1 111 ? 7.244 -20.309 17.544 1.00 34.93 ? 131 ARG B N 1 ATOM 6611 C CA . ARG B 1 111 ? 6.589 -21.621 17.664 1.00 33.83 ? 131 ARG B CA 1 ATOM 6612 C C . ARG B 1 111 ? 7.092 -22.558 16.556 1.00 33.01 ? 131 ARG B C 1 ATOM 6613 O O . ARG B 1 111 ? 6.439 -22.689 15.528 1.00 32.34 ? 131 ARG B O 1 ATOM 6614 C CB . ARG B 1 111 ? 5.059 -21.497 17.549 1.00 33.54 ? 131 ARG B CB 1 ATOM 6615 C CG . ARG B 1 111 ? 4.358 -20.845 18.727 1.00 33.11 ? 131 ARG B CG 1 ATOM 6616 C CD . ARG B 1 111 ? 2.830 -20.892 18.551 1.00 32.29 ? 131 ARG B CD 1 ATOM 6617 N NE . ARG B 1 111 ? 2.301 -22.246 18.709 1.00 31.62 ? 131 ARG B NE 1 ATOM 6618 C CZ . ARG B 1 111 ? 1.027 -22.603 18.532 1.00 31.35 ? 131 ARG B CZ 1 ATOM 6619 N NH1 . ARG B 1 111 ? 0.105 -21.714 18.187 1.00 31.90 ? 131 ARG B NH1 1 ATOM 6620 N NH2 . ARG B 1 111 ? 0.667 -23.866 18.706 1.00 31.45 ? 131 ARG B NH2 1 ATOM 6621 N N . PRO B 1 112 ? 8.247 -23.219 16.765 1.00 32.40 ? 132 PRO B N 1 ATOM 6622 C CA . PRO B 1 112 ? 8.768 -24.124 15.732 1.00 31.96 ? 132 PRO B CA 1 ATOM 6623 C C . PRO B 1 112 ? 7.774 -25.220 15.370 1.00 31.39 ? 132 PRO B C 1 ATOM 6624 O O . PRO B 1 112 ? 7.242 -25.886 16.256 1.00 31.51 ? 132 PRO B O 1 ATOM 6625 C CB . PRO B 1 112 ? 10.018 -24.734 16.387 1.00 31.97 ? 132 PRO B CB 1 ATOM 6626 C CG . PRO B 1 112 ? 10.431 -23.744 17.415 1.00 32.31 ? 132 PRO B CG 1 ATOM 6627 C CD . PRO B 1 112 ? 9.148 -23.142 17.930 1.00 32.51 ? 132 PRO B CD 1 ATOM 6628 N N . GLY B 1 113 ? 7.522 -25.399 14.081 1.00 30.85 ? 133 GLY B N 1 ATOM 6629 C CA . GLY B 1 113 ? 6.579 -26.417 13.618 1.00 30.52 ? 133 GLY B CA 1 ATOM 6630 C C . GLY B 1 113 ? 5.142 -25.952 13.436 1.00 30.33 ? 133 GLY B C 1 ATOM 6631 O O . GLY B 1 113 ? 4.353 -26.646 12.811 1.00 30.53 ? 133 GLY B O 1 ATOM 6632 N N . TYR B 1 114 ? 4.786 -24.792 13.986 1.00 30.27 ? 134 TYR B N 1 ATOM 6633 C CA . TYR B 1 114 ? 3.424 -24.272 13.865 1.00 30.19 ? 134 TYR B CA 1 ATOM 6634 C C . TYR B 1 114 ? 3.271 -23.531 12.547 1.00 29.94 ? 134 TYR B C 1 ATOM 6635 O O . TYR B 1 114 ? 4.026 -22.611 12.269 1.00 29.91 ? 134 TYR B O 1 ATOM 6636 C CB . TYR B 1 114 ? 3.100 -23.331 15.025 1.00 30.40 ? 134 TYR B CB 1 ATOM 6637 C CG . TYR B 1 114 ? 1.706 -22.743 14.976 1.00 29.58 ? 134 TYR B CG 1 ATOM 6638 C CD1 . TYR B 1 114 ? 1.510 -21.370 14.860 1.00 28.80 ? 134 TYR B CD1 1 ATOM 6639 C CD2 . TYR B 1 114 ? 0.584 -23.557 15.044 1.00 29.43 ? 134 TYR B CD2 1 ATOM 6640 C CE1 . TYR B 1 114 ? 0.222 -20.820 14.814 1.00 27.59 ? 134 TYR B CE1 1 ATOM 6641 C CE2 . TYR B 1 114 ? -0.707 -23.015 15.006 1.00 28.65 ? 134 TYR B CE2 1 ATOM 6642 C CZ . TYR B 1 114 ? -0.875 -21.641 14.891 1.00 27.47 ? 134 TYR B CZ 1 ATOM 6643 O OH . TYR B 1 114 ? -2.140 -21.095 14.845 1.00 24.78 ? 134 TYR B OH 1 ATOM 6644 N N . GLN B 1 115 ? 2.280 -23.923 11.753 1.00 29.89 ? 135 GLN B N 1 ATOM 6645 C CA . GLN B 1 115 ? 2.131 -23.409 10.392 1.00 30.22 ? 135 GLN B CA 1 ATOM 6646 C C . GLN B 1 115 ? 0.898 -22.518 10.170 1.00 30.09 ? 135 GLN B C 1 ATOM 6647 O O . GLN B 1 115 ? 0.752 -21.962 9.084 1.00 30.46 ? 135 GLN B O 1 ATOM 6648 C CB . GLN B 1 115 ? 2.122 -24.585 9.403 1.00 30.58 ? 135 GLN B CB 1 ATOM 6649 C CG . GLN B 1 115 ? 3.359 -25.456 9.542 1.00 31.90 ? 135 GLN B CG 1 ATOM 6650 C CD . GLN B 1 115 ? 3.390 -26.653 8.621 1.00 34.53 ? 135 GLN B CD 1 ATOM 6651 O OE1 . GLN B 1 115 ? 2.414 -26.974 7.945 1.00 36.92 ? 135 GLN B OE1 1 ATOM 6652 N NE2 . GLN B 1 115 ? 4.528 -27.339 8.603 1.00 35.82 ? 135 GLN B NE2 1 ATOM 6653 N N . SER B 1 116 ? 0.052 -22.341 11.191 1.00 29.27 ? 136 SER B N 1 ATOM 6654 C CA . SER B 1 116 ? -1.256 -21.682 11.006 1.00 28.81 ? 136 SER B CA 1 ATOM 6655 C C . SER B 1 116 ? -1.307 -20.235 11.496 1.00 28.38 ? 136 SER B C 1 ATOM 6656 O O . SER B 1 116 ? -2.392 -19.669 11.679 1.00 28.44 ? 136 SER B O 1 ATOM 6657 C CB . SER B 1 116 ? -2.356 -22.496 11.685 1.00 28.61 ? 136 SER B CB 1 ATOM 6658 O OG . SER B 1 116 ? -2.537 -23.730 11.026 1.00 28.21 ? 136 SER B OG 1 ATOM 6659 N N . SER B 1 117 ? -0.133 -19.637 11.681 1.00 27.31 ? 137 SER B N 1 ATOM 6660 C CA . SER B 1 117 ? -0.009 -18.266 12.165 1.00 26.80 ? 137 SER B CA 1 ATOM 6661 C C . SER B 1 117 ? -0.941 -17.272 11.460 1.00 26.37 ? 137 SER B C 1 ATOM 6662 O O . SER B 1 117 ? -1.645 -16.495 12.101 1.00 25.97 ? 137 SER B O 1 ATOM 6663 C CB . SER B 1 117 ? 1.439 -17.806 11.991 1.00 26.71 ? 137 SER B CB 1 ATOM 6664 O OG . SER B 1 117 ? 1.561 -16.435 12.227 1.00 26.73 ? 137 SER B OG 1 ATOM 6665 N N . TRP B 1 118 ? -0.928 -17.296 10.135 1.00 25.71 ? 138 TRP B N 1 ATOM 6666 C CA . TRP B 1 118 ? -1.689 -16.331 9.363 1.00 25.21 ? 138 TRP B CA 1 ATOM 6667 C C . TRP B 1 118 ? -3.194 -16.570 9.540 1.00 25.12 ? 138 TRP B C 1 ATOM 6668 O O . TRP B 1 118 ? -3.965 -15.623 9.678 1.00 25.27 ? 138 TRP B O 1 ATOM 6669 C CB . TRP B 1 118 ? -1.296 -16.412 7.888 1.00 25.11 ? 138 TRP B CB 1 ATOM 6670 C CG . TRP B 1 118 ? -1.834 -15.294 7.040 1.00 24.80 ? 138 TRP B CG 1 ATOM 6671 C CD1 . TRP B 1 118 ? -2.738 -15.398 6.024 1.00 23.62 ? 138 TRP B CD1 1 ATOM 6672 C CD2 . TRP B 1 118 ? -1.477 -13.912 7.123 1.00 24.02 ? 138 TRP B CD2 1 ATOM 6673 N NE1 . TRP B 1 118 ? -2.964 -14.168 5.468 1.00 24.99 ? 138 TRP B NE1 1 ATOM 6674 C CE2 . TRP B 1 118 ? -2.207 -13.235 6.129 1.00 24.25 ? 138 TRP B CE2 1 ATOM 6675 C CE3 . TRP B 1 118 ? -0.609 -13.180 7.942 1.00 24.78 ? 138 TRP B CE3 1 ATOM 6676 C CZ2 . TRP B 1 118 ? -2.110 -11.858 5.939 1.00 24.61 ? 138 TRP B CZ2 1 ATOM 6677 C CZ3 . TRP B 1 118 ? -0.517 -11.808 7.757 1.00 25.19 ? 138 TRP B CZ3 1 ATOM 6678 C CH2 . TRP B 1 118 ? -1.255 -11.164 6.754 1.00 25.16 ? 138 TRP B CH2 1 ATOM 6679 N N . ALA B 1 119 ? -3.596 -17.837 9.550 1.00 24.78 ? 139 ALA B N 1 ATOM 6680 C CA . ALA B 1 119 ? -4.995 -18.211 9.736 1.00 24.46 ? 139 ALA B CA 1 ATOM 6681 C C . ALA B 1 119 ? -5.508 -17.789 11.108 1.00 24.15 ? 139 ALA B C 1 ATOM 6682 O O . ALA B 1 119 ? -6.696 -17.500 11.273 1.00 23.69 ? 139 ALA B O 1 ATOM 6683 C CB . ALA B 1 119 ? -5.152 -19.698 9.568 1.00 24.32 ? 139 ALA B CB 1 ATOM 6684 N N . SER B 1 120 ? -4.595 -17.760 12.079 1.00 23.95 ? 140 SER B N 1 ATOM 6685 C CA . SER B 1 120 ? -4.925 -17.494 13.479 1.00 23.77 ? 140 SER B CA 1 ATOM 6686 C C . SER B 1 120 ? -5.182 -16.024 13.739 1.00 23.76 ? 140 SER B C 1 ATOM 6687 O O . SER B 1 120 ? -5.748 -15.669 14.771 1.00 24.00 ? 140 SER B O 1 ATOM 6688 C CB . SER B 1 120 ? -3.778 -17.953 14.402 1.00 23.65 ? 140 SER B CB 1 ATOM 6689 O OG . SER B 1 120 ? -2.714 -16.999 14.428 1.00 22.87 ? 140 SER B OG 1 ATOM 6690 N N . ARG B 1 121 ? -4.742 -15.166 12.822 1.00 23.63 ? 141 ARG B N 1 ATOM 6691 C CA . ARG B 1 121 ? -4.750 -13.732 13.073 1.00 23.33 ? 141 ARG B CA 1 ATOM 6692 C C . ARG B 1 121 ? -6.183 -13.193 13.123 1.00 23.10 ? 141 ARG B C 1 ATOM 6693 O O . ARG B 1 121 ? -7.086 -13.745 12.474 1.00 22.83 ? 141 ARG B O 1 ATOM 6694 C CB . ARG B 1 121 ? -3.925 -12.992 12.010 1.00 23.65 ? 141 ARG B CB 1 ATOM 6695 C CG . ARG B 1 121 ? -4.693 -12.703 10.714 1.00 23.81 ? 141 ARG B CG 1 ATOM 6696 C CD . ARG B 1 121 ? -3.780 -12.274 9.581 1.00 23.57 ? 141 ARG B CD 1 ATOM 6697 N NE . ARG B 1 121 ? -4.564 -11.855 8.421 1.00 22.87 ? 141 ARG B NE 1 ATOM 6698 C CZ . ARG B 1 121 ? -5.204 -12.674 7.589 1.00 23.10 ? 141 ARG B CZ 1 ATOM 6699 N NH1 . ARG B 1 121 ? -5.158 -13.994 7.746 1.00 23.00 ? 141 ARG B NH1 1 ATOM 6700 N NH2 . ARG B 1 121 ? -5.895 -12.165 6.576 1.00 23.90 ? 141 ARG B NH2 1 ATOM 6701 N N . PRO B 1 122 ? -6.400 -12.124 13.907 1.00 22.99 ? 142 PRO B N 1 ATOM 6702 C CA . PRO B 1 122 ? -7.719 -11.489 13.959 1.00 22.76 ? 142 PRO B CA 1 ATOM 6703 C C . PRO B 1 122 ? -8.203 -10.918 12.622 1.00 22.93 ? 142 PRO B C 1 ATOM 6704 O O . PRO B 1 122 ? -7.396 -10.590 11.735 1.00 22.51 ? 142 PRO B O 1 ATOM 6705 C CB . PRO B 1 122 ? -7.521 -10.355 14.963 1.00 22.97 ? 142 PRO B CB 1 ATOM 6706 C CG . PRO B 1 122 ? -6.424 -10.830 15.855 1.00 23.05 ? 142 PRO B CG 1 ATOM 6707 C CD . PRO B 1 122 ? -5.501 -11.605 14.958 1.00 22.64 ? 142 PRO B CD 1 ATOM 6708 N N . ILE B 1 123 ? -9.523 -10.795 12.496 1.00 22.58 ? 143 ILE B N 1 ATOM 6709 C CA . ILE B 1 123 ? -10.124 -10.113 11.356 1.00 22.54 ? 143 ILE B CA 1 ATOM 6710 C C . ILE B 1 123 ? -9.828 -8.617 11.475 1.00 23.09 ? 143 ILE B C 1 ATOM 6711 O O . ILE B 1 123 ? -9.409 -8.143 12.542 1.00 24.00 ? 143 ILE B O 1 ATOM 6712 C CB . ILE B 1 123 ? -11.643 -10.445 11.251 1.00 22.41 ? 143 ILE B CB 1 ATOM 6713 C CG1 . ILE B 1 123 ? -12.184 -10.135 9.852 1.00 21.82 ? 143 ILE B CG1 1 ATOM 6714 C CG2 . ILE B 1 123 ? -12.447 -9.746 12.356 1.00 20.84 ? 143 ILE B CG2 1 ATOM 6715 C CD1 . ILE B 1 123 ? -13.335 -11.026 9.455 1.00 22.45 ? 143 ILE B CD1 1 ATOM 6716 N N . SER B 1 124 ? -9.981 -7.891 10.374 1.00 23.47 ? 144 SER B N 1 ATOM 6717 C CA . SER B 1 124 ? -9.648 -6.469 10.303 1.00 23.91 ? 144 SER B CA 1 ATOM 6718 C C . SER B 1 124 ? -10.656 -5.707 9.444 1.00 24.26 ? 144 SER B C 1 ATOM 6719 O O . SER B 1 124 ? -11.435 -6.292 8.697 1.00 24.54 ? 144 SER B O 1 ATOM 6720 C CB . SER B 1 124 ? -8.246 -6.267 9.720 1.00 24.22 ? 144 SER B CB 1 ATOM 6721 O OG . SER B 1 124 ? -8.196 -6.667 8.364 1.00 24.40 ? 144 SER B OG 1 ATOM 6722 N N . THR B 1 125 ? -10.638 -4.391 9.570 1.00 24.57 ? 145 THR B N 1 ATOM 6723 C CA . THR B 1 125 ? -11.487 -3.537 8.761 1.00 24.91 ? 145 THR B CA 1 ATOM 6724 C C . THR B 1 125 ? -11.308 -3.835 7.272 1.00 24.61 ? 145 THR B C 1 ATOM 6725 O O . THR B 1 125 ? -12.287 -4.052 6.556 1.00 24.61 ? 145 THR B O 1 ATOM 6726 C CB . THR B 1 125 ? -11.223 -2.059 9.093 1.00 25.14 ? 145 THR B CB 1 ATOM 6727 O OG1 . THR B 1 125 ? -11.634 -1.816 10.450 1.00 25.61 ? 145 THR B OG1 1 ATOM 6728 C CG2 . THR B 1 125 ? -12.001 -1.130 8.157 1.00 25.92 ? 145 THR B CG2 1 ATOM 6729 N N . ALA B 1 126 ? -10.062 -3.902 6.822 1.00 24.09 ? 146 ALA B N 1 ATOM 6730 C CA . ALA B 1 126 ? -9.778 -4.175 5.416 1.00 24.00 ? 146 ALA B CA 1 ATOM 6731 C C . ALA B 1 126 ? -10.321 -5.534 4.979 1.00 23.85 ? 146 ALA B C 1 ATOM 6732 O O . ALA B 1 126 ? -10.811 -5.680 3.857 1.00 23.90 ? 146 ALA B O 1 ATOM 6733 C CB . ALA B 1 126 ? -8.275 -4.071 5.139 1.00 23.86 ? 146 ALA B CB 1 ATOM 6734 N N . GLU B 1 127 ? -10.258 -6.527 5.862 1.00 23.94 ? 147 GLU B N 1 ATOM 6735 C CA . GLU B 1 127 ? -10.760 -7.853 5.524 1.00 23.88 ? 147 GLU B CA 1 ATOM 6736 C C . GLU B 1 127 ? -12.284 -7.819 5.387 1.00 24.30 ? 147 GLU B C 1 ATOM 6737 O O . GLU B 1 127 ? -12.843 -8.460 4.487 1.00 24.57 ? 147 GLU B O 1 ATOM 6738 C CB . GLU B 1 127 ? -10.323 -8.884 6.559 1.00 23.98 ? 147 GLU B CB 1 ATOM 6739 C CG . GLU B 1 127 ? -10.588 -10.306 6.114 1.00 23.50 ? 147 GLU B CG 1 ATOM 6740 C CD . GLU B 1 127 ? -9.831 -11.327 6.907 1.00 22.75 ? 147 GLU B CD 1 ATOM 6741 O OE1 . GLU B 1 127 ? -9.266 -10.986 7.968 1.00 23.85 ? 147 GLU B OE1 1 ATOM 6742 O OE2 . GLU B 1 127 ? -9.808 -12.486 6.467 1.00 21.39 ? 147 GLU B OE2 1 ATOM 6743 N N . TYR B 1 128 ? -12.937 -7.036 6.248 1.00 24.26 ? 148 TYR B N 1 ATOM 6744 C CA . TYR B 1 128 ? -14.386 -6.813 6.167 1.00 24.58 ? 148 TYR B CA 1 ATOM 6745 C C . TYR B 1 128 ? -14.839 -6.133 4.877 1.00 24.92 ? 148 TYR B C 1 ATOM 6746 O O . TYR B 1 128 ? -15.817 -6.564 4.255 1.00 25.03 ? 148 TYR B O 1 ATOM 6747 C CB . TYR B 1 128 ? -14.873 -5.989 7.361 1.00 24.44 ? 148 TYR B CB 1 ATOM 6748 C CG . TYR B 1 128 ? -15.089 -6.792 8.619 1.00 24.64 ? 148 TYR B CG 1 ATOM 6749 C CD1 . TYR B 1 128 ? -15.910 -7.910 8.610 1.00 25.52 ? 148 TYR B CD1 1 ATOM 6750 C CD2 . TYR B 1 128 ? -14.517 -6.408 9.832 1.00 25.08 ? 148 TYR B CD2 1 ATOM 6751 C CE1 . TYR B 1 128 ? -16.136 -8.650 9.759 1.00 24.84 ? 148 TYR B CE1 1 ATOM 6752 C CE2 . TYR B 1 128 ? -14.738 -7.143 10.991 1.00 24.90 ? 148 TYR B CE2 1 ATOM 6753 C CZ . TYR B 1 128 ? -15.560 -8.268 10.940 1.00 24.77 ? 148 TYR B CZ 1 ATOM 6754 O OH . TYR B 1 128 ? -15.811 -9.021 12.060 1.00 21.16 ? 148 TYR B OH 1 ATOM 6755 N N . ALA B 1 129 ? -14.144 -5.071 4.476 1.00 25.26 ? 149 ALA B N 1 ATOM 6756 C CA . ALA B 1 129 ? -14.430 -4.414 3.196 1.00 25.74 ? 149 ALA B CA 1 ATOM 6757 C C . ALA B 1 129 ? -14.330 -5.409 2.033 1.00 26.21 ? 149 ALA B C 1 ATOM 6758 O O . ALA B 1 129 ? -15.141 -5.375 1.106 1.00 26.71 ? 149 ALA B O 1 ATOM 6759 C CB . ALA B 1 129 ? -13.492 -3.219 2.966 1.00 25.64 ? 149 ALA B CB 1 ATOM 6760 N N . LEU B 1 130 ? -13.355 -6.309 2.098 1.00 26.35 ? 150 LEU B N 1 ATOM 6761 C CA . LEU B 1 130 ? -13.185 -7.307 1.051 1.00 26.67 ? 150 LEU B CA 1 ATOM 6762 C C . LEU B 1 130 ? -14.260 -8.396 1.130 1.00 26.75 ? 150 LEU B C 1 ATOM 6763 O O . LEU B 1 130 ? -14.774 -8.840 0.108 1.00 26.41 ? 150 LEU B O 1 ATOM 6764 C CB . LEU B 1 130 ? -11.780 -7.897 1.103 1.00 26.42 ? 150 LEU B CB 1 ATOM 6765 C CG . LEU B 1 130 ? -10.684 -6.906 0.693 1.00 26.99 ? 150 LEU B CG 1 ATOM 6766 C CD1 . LEU B 1 130 ? -9.286 -7.397 1.103 1.00 27.64 ? 150 LEU B CD1 1 ATOM 6767 C CD2 . LEU B 1 130 ? -10.734 -6.640 -0.815 1.00 25.91 ? 150 LEU B CD2 1 ATOM 6768 N N . LEU B 1 131 ? -14.602 -8.821 2.341 1.00 27.47 ? 151 LEU B N 1 ATOM 6769 C CA . LEU B 1 131 ? -15.688 -9.784 2.531 1.00 27.71 ? 151 LEU B CA 1 ATOM 6770 C C . LEU B 1 131 ? -16.991 -9.254 1.962 1.00 28.26 ? 151 LEU B C 1 ATOM 6771 O O . LEU B 1 131 ? -17.699 -9.962 1.256 1.00 27.84 ? 151 LEU B O 1 ATOM 6772 C CB . LEU B 1 131 ? -15.883 -10.110 4.015 1.00 27.69 ? 151 LEU B CB 1 ATOM 6773 C CG . LEU B 1 131 ? -14.973 -11.205 4.566 1.00 28.04 ? 151 LEU B CG 1 ATOM 6774 C CD1 . LEU B 1 131 ? -15.115 -11.274 6.081 1.00 27.46 ? 151 LEU B CD1 1 ATOM 6775 C CD2 . LEU B 1 131 ? -15.296 -12.557 3.908 1.00 26.70 ? 151 LEU B CD2 1 ATOM 6776 N N . TYR B 1 132 ? -17.296 -8.001 2.283 1.00 29.23 ? 152 TYR B N 1 ATOM 6777 C CA . TYR B 1 132 ? -18.524 -7.363 1.832 1.00 30.24 ? 152 TYR B CA 1 ATOM 6778 C C . TYR B 1 132 ? -18.549 -7.316 0.301 1.00 30.20 ? 152 TYR B C 1 ATOM 6779 O O . TYR B 1 132 ? -19.579 -7.578 -0.319 1.00 29.89 ? 152 TYR B O 1 ATOM 6780 C CB . TYR B 1 132 ? -18.646 -5.959 2.442 1.00 30.83 ? 152 TYR B CB 1 ATOM 6781 C CG . TYR B 1 132 ? -20.046 -5.385 2.413 1.00 33.45 ? 152 TYR B CG 1 ATOM 6782 C CD1 . TYR B 1 132 ? -20.982 -5.731 3.381 1.00 36.19 ? 152 TYR B CD1 1 ATOM 6783 C CD2 . TYR B 1 132 ? -20.433 -4.483 1.416 1.00 36.91 ? 152 TYR B CD2 1 ATOM 6784 C CE1 . TYR B 1 132 ? -22.273 -5.208 3.365 1.00 37.89 ? 152 TYR B CE1 1 ATOM 6785 C CE2 . TYR B 1 132 ? -21.730 -3.950 1.385 1.00 38.26 ? 152 TYR B CE2 1 ATOM 6786 C CZ . TYR B 1 132 ? -22.644 -4.319 2.360 1.00 39.59 ? 152 TYR B CZ 1 ATOM 6787 O OH . TYR B 1 132 ? -23.929 -3.797 2.343 1.00 41.82 ? 152 TYR B OH 1 ATOM 6788 N N . HIS B 1 133 ? -17.405 -7.014 -0.308 1.00 30.29 ? 153 HIS B N 1 ATOM 6789 C CA . HIS B 1 133 ? -17.315 -6.990 -1.767 1.00 30.04 ? 153 HIS B CA 1 ATOM 6790 C C . HIS B 1 133 ? -17.601 -8.375 -2.328 1.00 29.66 ? 153 HIS B C 1 ATOM 6791 O O . HIS B 1 133 ? -18.317 -8.505 -3.315 1.00 29.90 ? 153 HIS B O 1 ATOM 6792 C CB . HIS B 1 133 ? -15.937 -6.505 -2.230 1.00 30.12 ? 153 HIS B CB 1 ATOM 6793 C CG . HIS B 1 133 ? -15.728 -6.608 -3.707 0.50 30.01 ? 153 HIS B CG 1 ATOM 6794 N ND1 . HIS B 1 133 ? -16.398 -5.811 -4.609 0.50 30.30 ? 153 HIS B ND1 1 ATOM 6795 C CD2 . HIS B 1 133 ? -14.928 -7.417 -4.439 0.50 30.05 ? 153 HIS B CD2 1 ATOM 6796 C CE1 . HIS B 1 133 ? -16.019 -6.124 -5.834 0.50 29.43 ? 153 HIS B CE1 1 ATOM 6797 N NE2 . HIS B 1 133 ? -15.125 -7.093 -5.758 0.50 30.02 ? 153 HIS B NE2 1 ATOM 6798 N N . THR B 1 134 ? -17.038 -9.401 -1.690 1.00 29.26 ? 154 THR B N 1 ATOM 6799 C CA . THR B 1 134 ? -17.248 -10.783 -2.102 1.00 29.04 ? 154 THR B CA 1 ATOM 6800 C C . THR B 1 134 ? -18.733 -11.151 -1.997 1.00 29.23 ? 154 THR B C 1 ATOM 6801 O O . THR B 1 134 ? -19.286 -11.739 -2.914 1.00 28.94 ? 154 THR B O 1 ATOM 6802 C CB . THR B 1 134 ? -16.391 -11.762 -1.255 1.00 29.18 ? 154 THR B CB 1 ATOM 6803 O OG1 . THR B 1 134 ? -15.003 -11.440 -1.401 1.00 29.14 ? 154 THR B OG1 1 ATOM 6804 C CG2 . THR B 1 134 ? -16.618 -13.208 -1.663 1.00 27.97 ? 154 THR B CG2 1 ATOM 6805 N N . LEU B 1 135 ? -19.379 -10.780 -0.895 1.00 29.48 ? 155 LEU B N 1 ATOM 6806 C CA . LEU B 1 135 ? -20.797 -11.089 -0.714 1.00 29.97 ? 155 LEU B CA 1 ATOM 6807 C C . LEU B 1 135 ? -21.641 -10.387 -1.755 1.00 30.11 ? 155 LEU B C 1 ATOM 6808 O O . LEU B 1 135 ? -22.518 -10.994 -2.353 1.00 30.17 ? 155 LEU B O 1 ATOM 6809 C CB . LEU B 1 135 ? -21.299 -10.670 0.669 1.00 30.40 ? 155 LEU B CB 1 ATOM 6810 C CG . LEU B 1 135 ? -21.116 -11.591 1.869 1.00 30.34 ? 155 LEU B CG 1 ATOM 6811 C CD1 . LEU B 1 135 ? -21.981 -11.056 3.020 1.00 29.79 ? 155 LEU B CD1 1 ATOM 6812 C CD2 . LEU B 1 135 ? -21.477 -13.033 1.542 1.00 30.78 ? 155 LEU B CD2 1 ATOM 6813 N N . GLN B 1 136 ? -21.370 -9.101 -1.955 1.00 30.35 ? 156 GLN B N 1 ATOM 6814 C CA . GLN B 1 136 ? -22.117 -8.298 -2.905 1.00 30.44 ? 156 GLN B CA 1 ATOM 6815 C C . GLN B 1 136 ? -22.085 -8.950 -4.284 1.00 30.35 ? 156 GLN B C 1 ATOM 6816 O O . GLN B 1 136 ? -23.121 -9.087 -4.935 1.00 30.75 ? 156 GLN B O 1 ATOM 6817 C CB . GLN B 1 136 ? -21.572 -6.864 -2.957 1.00 30.52 ? 156 GLN B CB 1 ATOM 6818 N N . GLU B 1 137 ? -20.903 -9.383 -4.701 1.00 29.83 ? 157 GLU B N 1 ATOM 6819 C CA . GLU B 1 137 ? -20.732 -10.032 -5.992 1.00 29.69 ? 157 GLU B CA 1 ATOM 6820 C C . GLU B 1 137 ? -21.327 -11.428 -6.016 1.00 28.88 ? 157 GLU B C 1 ATOM 6821 O O . GLU B 1 137 ? -22.116 -11.760 -6.903 1.00 28.45 ? 157 GLU B O 1 ATOM 6822 C CB . GLU B 1 137 ? -19.249 -10.122 -6.332 1.00 30.15 ? 157 GLU B CB 1 ATOM 6823 C CG . GLU B 1 137 ? -18.612 -8.771 -6.535 1.00 32.64 ? 157 GLU B CG 1 ATOM 6824 C CD . GLU B 1 137 ? -19.032 -8.134 -7.843 1.00 35.41 ? 157 GLU B CD 1 ATOM 6825 O OE1 . GLU B 1 137 ? -18.787 -8.746 -8.906 1.00 38.42 ? 157 GLU B OE1 1 ATOM 6826 O OE2 . GLU B 1 137 ? -19.606 -7.029 -7.808 1.00 36.81 ? 157 GLU B OE2 1 ATOM 6827 N N . ALA B 1 138 ? -20.946 -12.247 -5.041 1.00 27.80 ? 158 ALA B N 1 ATOM 6828 C CA . ALA B 1 138 ? -21.406 -13.629 -4.990 1.00 27.55 ? 158 ALA B CA 1 ATOM 6829 C C . ALA B 1 138 ? -22.932 -13.777 -4.873 1.00 27.03 ? 158 ALA B C 1 ATOM 6830 O O . ALA B 1 138 ? -23.477 -14.785 -5.332 1.00 27.21 ? 158 ALA B O 1 ATOM 6831 C CB . ALA B 1 138 ? -20.715 -14.381 -3.860 1.00 27.42 ? 158 ALA B CB 1 ATOM 6832 N N . THR B 1 139 ? -23.616 -12.797 -4.279 1.00 26.03 ? 159 THR B N 1 ATOM 6833 C CA . THR B 1 139 ? -25.068 -12.908 -4.076 1.00 25.59 ? 159 THR B CA 1 ATOM 6834 C C . THR B 1 139 ? -25.945 -12.224 -5.136 1.00 25.93 ? 159 THR B C 1 ATOM 6835 O O . THR B 1 139 ? -27.163 -12.222 -5.008 1.00 25.86 ? 159 THR B O 1 ATOM 6836 C CB . THR B 1 139 ? -25.493 -12.424 -2.667 1.00 25.61 ? 159 THR B CB 1 ATOM 6837 O OG1 . THR B 1 139 ? -25.233 -11.021 -2.520 1.00 23.73 ? 159 THR B OG1 1 ATOM 6838 C CG2 . THR B 1 139 ? -24.764 -13.219 -1.593 1.00 23.96 ? 159 THR B CG2 1 ATOM 6839 N N . LYS B 1 140 ? -25.345 -11.696 -6.200 1.00 26.43 ? 160 LYS B N 1 ATOM 6840 C CA . LYS B 1 140 ? -26.121 -11.053 -7.272 1.00 26.99 ? 160 LYS B CA 1 ATOM 6841 C C . LYS B 1 140 ? -27.288 -11.906 -7.811 1.00 26.49 ? 160 LYS B C 1 ATOM 6842 O O . LYS B 1 140 ? -28.358 -11.376 -8.080 1.00 26.13 ? 160 LYS B O 1 ATOM 6843 C CB . LYS B 1 140 ? -25.205 -10.623 -8.427 1.00 27.32 ? 160 LYS B CB 1 ATOM 6844 C CG . LYS B 1 140 ? -24.276 -9.486 -8.045 1.00 29.09 ? 160 LYS B CG 1 ATOM 6845 C CD . LYS B 1 140 ? -23.657 -8.826 -9.253 1.00 31.00 ? 160 LYS B CD 1 ATOM 6846 C CE . LYS B 1 140 ? -22.625 -7.802 -8.816 1.00 32.35 ? 160 LYS B CE 1 ATOM 6847 N NZ . LYS B 1 140 ? -22.303 -6.830 -9.885 1.00 34.19 ? 160 LYS B NZ 1 ATOM 6848 N N . PRO B 1 141 ? -27.082 -13.225 -7.967 1.00 26.00 ? 161 PRO B N 1 ATOM 6849 C CA . PRO B 1 141 ? -28.189 -14.067 -8.411 1.00 25.86 ? 161 PRO B CA 1 ATOM 6850 C C . PRO B 1 141 ? -29.390 -14.070 -7.461 1.00 25.93 ? 161 PRO B C 1 ATOM 6851 O O . PRO B 1 141 ? -30.507 -14.355 -7.891 1.00 25.94 ? 161 PRO B O 1 ATOM 6852 C CB . PRO B 1 141 ? -27.561 -15.464 -8.476 1.00 25.72 ? 161 PRO B CB 1 ATOM 6853 C CG . PRO B 1 141 ? -26.104 -15.220 -8.633 1.00 25.56 ? 161 PRO B CG 1 ATOM 6854 C CD . PRO B 1 141 ? -25.825 -13.988 -7.849 1.00 25.85 ? 161 PRO B CD 1 ATOM 6855 N N . LEU B 1 142 ? -29.154 -13.753 -6.185 1.00 25.92 ? 162 LEU B N 1 ATOM 6856 C CA . LEU B 1 142 ? -30.201 -13.733 -5.160 1.00 25.47 ? 162 LEU B CA 1 ATOM 6857 C C . LEU B 1 142 ? -30.891 -12.370 -5.006 1.00 25.34 ? 162 LEU B C 1 ATOM 6858 O O . LEU B 1 142 ? -31.712 -12.179 -4.095 1.00 24.63 ? 162 LEU B O 1 ATOM 6859 C CB . LEU B 1 142 ? -29.609 -14.157 -3.811 1.00 25.42 ? 162 LEU B CB 1 ATOM 6860 C CG . LEU B 1 142 ? -29.231 -15.630 -3.653 1.00 25.58 ? 162 LEU B CG 1 ATOM 6861 C CD1 . LEU B 1 142 ? -28.698 -15.874 -2.245 1.00 25.21 ? 162 LEU B CD1 1 ATOM 6862 C CD2 . LEU B 1 142 ? -30.434 -16.532 -3.937 1.00 25.53 ? 162 LEU B CD2 1 ATOM 6863 N N . HIS B 1 143 ? -30.581 -11.431 -5.896 1.00 25.25 ? 163 HIS B N 1 ATOM 6864 C CA . HIS B 1 143 ? -31.116 -10.077 -5.778 1.00 25.36 ? 163 HIS B CA 1 ATOM 6865 C C . HIS B 1 143 ? -32.641 -10.011 -5.657 1.00 25.28 ? 163 HIS B C 1 ATOM 6866 O O . HIS B 1 143 ? -33.158 -9.373 -4.732 1.00 24.76 ? 163 HIS B O 1 ATOM 6867 C CB . HIS B 1 143 ? -30.647 -9.188 -6.931 1.00 25.68 ? 163 HIS B CB 1 ATOM 6868 C CG . HIS B 1 143 ? -30.976 -7.742 -6.732 1.00 26.28 ? 163 HIS B CG 1 ATOM 6869 N ND1 . HIS B 1 143 ? -30.333 -6.955 -5.798 1.00 26.69 ? 163 HIS B ND1 1 ATOM 6870 C CD2 . HIS B 1 143 ? -31.899 -6.946 -7.325 1.00 27.05 ? 163 HIS B CD2 1 ATOM 6871 C CE1 . HIS B 1 143 ? -30.836 -5.733 -5.836 1.00 26.30 ? 163 HIS B CE1 1 ATOM 6872 N NE2 . HIS B 1 143 ? -31.791 -5.703 -6.749 1.00 27.18 ? 163 HIS B NE2 1 ATOM 6873 N N . GLN B 1 144 ? -33.356 -10.657 -6.583 1.00 25.40 ? 164 GLN B N 1 ATOM 6874 C CA . GLN B 1 144 ? -34.828 -10.683 -6.533 1.00 25.24 ? 164 GLN B CA 1 ATOM 6875 C C . GLN B 1 144 ? -35.345 -11.468 -5.323 1.00 25.04 ? 164 GLN B C 1 ATOM 6876 O O . GLN B 1 144 ? -36.377 -11.123 -4.729 1.00 25.26 ? 164 GLN B O 1 ATOM 6877 C CB . GLN B 1 144 ? -35.405 -11.279 -7.825 1.00 25.31 ? 164 GLN B CB 1 ATOM 6878 N N . PHE B 1 145 ? -34.637 -12.536 -4.975 1.00 24.76 ? 165 PHE B N 1 ATOM 6879 C CA . PHE B 1 145 ? -34.969 -13.347 -3.799 1.00 24.78 ? 165 PHE B CA 1 ATOM 6880 C C . PHE B 1 145 ? -34.911 -12.476 -2.536 1.00 24.63 ? 165 PHE B C 1 ATOM 6881 O O . PHE B 1 145 ? -35.839 -12.491 -1.716 1.00 23.62 ? 165 PHE B O 1 ATOM 6882 C CB . PHE B 1 145 ? -34.009 -14.539 -3.711 1.00 24.80 ? 165 PHE B CB 1 ATOM 6883 C CG . PHE B 1 145 ? -34.047 -15.263 -2.403 1.00 25.95 ? 165 PHE B CG 1 ATOM 6884 C CD1 . PHE B 1 145 ? -35.009 -16.241 -2.165 1.00 26.37 ? 165 PHE B CD1 1 ATOM 6885 C CD2 . PHE B 1 145 ? -33.105 -14.979 -1.408 1.00 26.47 ? 165 PHE B CD2 1 ATOM 6886 C CE1 . PHE B 1 145 ? -35.045 -16.913 -0.956 1.00 26.72 ? 165 PHE B CE1 1 ATOM 6887 C CE2 . PHE B 1 145 ? -33.131 -15.651 -0.195 1.00 26.95 ? 165 PHE B CE2 1 ATOM 6888 C CZ . PHE B 1 145 ? -34.100 -16.619 0.033 1.00 27.01 ? 165 PHE B CZ 1 ATOM 6889 N N . PHE B 1 146 ? -33.826 -11.705 -2.417 1.00 24.40 ? 166 PHE B N 1 ATOM 6890 C CA . PHE B 1 146 ? -33.651 -10.759 -1.322 1.00 24.50 ? 166 PHE B CA 1 ATOM 6891 C C . PHE B 1 146 ? -34.803 -9.755 -1.270 1.00 25.04 ? 166 PHE B C 1 ATOM 6892 O O . PHE B 1 146 ? -35.402 -9.536 -0.216 1.00 24.86 ? 166 PHE B O 1 ATOM 6893 C CB . PHE B 1 146 ? -32.338 -9.970 -1.468 1.00 24.23 ? 166 PHE B CB 1 ATOM 6894 C CG . PHE B 1 146 ? -31.078 -10.765 -1.226 1.00 22.67 ? 166 PHE B CG 1 ATOM 6895 C CD1 . PHE B 1 146 ? -31.040 -11.835 -0.362 1.00 22.47 ? 166 PHE B CD1 1 ATOM 6896 C CD2 . PHE B 1 146 ? -29.891 -10.373 -1.830 1.00 22.77 ? 166 PHE B CD2 1 ATOM 6897 C CE1 . PHE B 1 146 ? -29.842 -12.529 -0.135 1.00 22.95 ? 166 PHE B CE1 1 ATOM 6898 C CE2 . PHE B 1 146 ? -28.708 -11.057 -1.605 1.00 21.80 ? 166 PHE B CE2 1 ATOM 6899 C CZ . PHE B 1 146 ? -28.685 -12.132 -0.753 1.00 21.73 ? 166 PHE B CZ 1 ATOM 6900 N N . LEU B 1 147 ? -35.103 -9.139 -2.408 1.00 25.28 ? 167 LEU B N 1 ATOM 6901 C CA . LEU B 1 147 ? -36.141 -8.119 -2.452 1.00 25.66 ? 167 LEU B CA 1 ATOM 6902 C C . LEU B 1 147 ? -37.479 -8.743 -2.064 1.00 25.66 ? 167 LEU B C 1 ATOM 6903 O O . LEU B 1 147 ? -38.173 -8.221 -1.204 1.00 25.03 ? 167 LEU B O 1 ATOM 6904 C CB . LEU B 1 147 ? -36.229 -7.450 -3.831 1.00 25.78 ? 167 LEU B CB 1 ATOM 6905 C CG . LEU B 1 147 ? -35.169 -6.407 -4.237 1.00 27.06 ? 167 LEU B CG 1 ATOM 6906 C CD1 . LEU B 1 147 ? -35.516 -5.856 -5.621 1.00 28.27 ? 167 LEU B CD1 1 ATOM 6907 C CD2 . LEU B 1 147 ? -35.054 -5.252 -3.242 1.00 27.42 ? 167 LEU B CD2 1 ATOM 6908 N N . ASN B 1 148 ? -37.815 -9.877 -2.671 1.00 26.23 ? 168 ASN B N 1 ATOM 6909 C CA . ASN B 1 148 ? -39.100 -10.533 -2.409 1.00 26.93 ? 168 ASN B CA 1 ATOM 6910 C C . ASN B 1 148 ? -39.271 -11.025 -0.973 1.00 26.39 ? 168 ASN B C 1 ATOM 6911 O O . ASN B 1 148 ? -40.383 -11.001 -0.445 1.00 26.31 ? 168 ASN B O 1 ATOM 6912 C CB . ASN B 1 148 ? -39.319 -11.716 -3.368 1.00 27.36 ? 168 ASN B CB 1 ATOM 6913 C CG . ASN B 1 148 ? -39.610 -11.276 -4.804 1.00 29.48 ? 168 ASN B CG 1 ATOM 6914 O OD1 . ASN B 1 148 ? -39.702 -10.079 -5.101 1.00 31.62 ? 168 ASN B OD1 1 ATOM 6915 N ND2 . ASN B 1 148 ? -39.749 -12.254 -5.706 1.00 30.18 ? 168 ASN B ND2 1 ATOM 6916 N N . THR B 1 149 ? -38.186 -11.485 -0.353 1.00 25.75 ? 169 THR B N 1 ATOM 6917 C CA . THR B 1 149 ? -38.277 -12.111 0.965 1.00 25.52 ? 169 THR B CA 1 ATOM 6918 C C . THR B 1 149 ? -38.043 -11.137 2.110 1.00 25.48 ? 169 THR B C 1 ATOM 6919 O O . THR B 1 149 ? -38.533 -11.367 3.229 1.00 25.68 ? 169 THR B O 1 ATOM 6920 C CB . THR B 1 149 ? -37.315 -13.317 1.087 1.00 25.68 ? 169 THR B CB 1 ATOM 6921 O OG1 . THR B 1 149 ? -35.964 -12.897 0.861 1.00 25.83 ? 169 THR B OG1 1 ATOM 6922 C CG2 . THR B 1 149 ? -37.691 -14.400 0.066 1.00 24.95 ? 169 THR B CG2 1 ATOM 6923 N N . THR B 1 150 ? -37.316 -10.048 1.838 1.00 24.78 ? 170 THR B N 1 ATOM 6924 C CA . THR B 1 150 ? -36.954 -9.087 2.883 1.00 24.43 ? 170 THR B CA 1 ATOM 6925 C C . THR B 1 150 ? -37.215 -7.612 2.563 1.00 24.42 ? 170 THR B C 1 ATOM 6926 O O . THR B 1 150 ? -37.225 -6.795 3.478 1.00 24.05 ? 170 THR B O 1 ATOM 6927 C CB . THR B 1 150 ? -35.451 -9.220 3.267 1.00 24.58 ? 170 THR B CB 1 ATOM 6928 O OG1 . THR B 1 150 ? -34.639 -8.598 2.263 1.00 22.25 ? 170 THR B OG1 1 ATOM 6929 C CG2 . THR B 1 150 ? -35.056 -10.681 3.440 1.00 23.96 ? 170 THR B CG2 1 ATOM 6930 N N . GLY B 1 151 ? -37.399 -7.266 1.286 1.00 24.37 ? 171 GLY B N 1 ATOM 6931 C CA . GLY B 1 151 ? -37.487 -5.862 0.865 1.00 24.61 ? 171 GLY B CA 1 ATOM 6932 C C . GLY B 1 151 ? -36.168 -5.096 0.960 1.00 24.80 ? 171 GLY B C 1 ATOM 6933 O O . GLY B 1 151 ? -36.142 -3.884 0.762 1.00 24.85 ? 171 GLY B O 1 ATOM 6934 N N . PHE B 1 152 ? -35.082 -5.802 1.284 1.00 24.61 ? 172 PHE B N 1 ATOM 6935 C CA . PHE B 1 152 ? -33.748 -5.228 1.412 1.00 24.59 ? 172 PHE B CA 1 ATOM 6936 C C . PHE B 1 152 ? -32.850 -5.958 0.418 1.00 24.79 ? 172 PHE B C 1 ATOM 6937 O O . PHE B 1 152 ? -33.235 -6.994 -0.120 1.00 25.40 ? 172 PHE B O 1 ATOM 6938 C CB . PHE B 1 152 ? -33.191 -5.460 2.826 1.00 24.53 ? 172 PHE B CB 1 ATOM 6939 C CG . PHE B 1 152 ? -33.768 -4.561 3.895 1.00 23.77 ? 172 PHE B CG 1 ATOM 6940 C CD1 . PHE B 1 152 ? -35.140 -4.369 4.027 1.00 24.13 ? 172 PHE B CD1 1 ATOM 6941 C CD2 . PHE B 1 152 ? -32.927 -3.947 4.805 1.00 23.83 ? 172 PHE B CD2 1 ATOM 6942 C CE1 . PHE B 1 152 ? -35.656 -3.561 5.027 1.00 24.42 ? 172 PHE B CE1 1 ATOM 6943 C CE2 . PHE B 1 152 ? -33.427 -3.130 5.812 1.00 24.76 ? 172 PHE B CE2 1 ATOM 6944 C CZ . PHE B 1 152 ? -34.797 -2.937 5.927 1.00 24.99 ? 172 PHE B CZ 1 ATOM 6945 N N . SER B 1 153 ? -31.655 -5.434 0.181 1.00 24.89 ? 173 SER B N 1 ATOM 6946 C CA . SER B 1 153 ? -30.691 -6.077 -0.714 1.00 25.19 ? 173 SER B CA 1 ATOM 6947 C C . SER B 1 153 ? -29.283 -5.535 -0.457 1.00 25.38 ? 173 SER B C 1 ATOM 6948 O O . SER B 1 153 ? -29.088 -4.732 0.443 1.00 24.66 ? 173 SER B O 1 ATOM 6949 C CB . SER B 1 153 ? -31.079 -5.832 -2.172 1.00 25.37 ? 173 SER B CB 1 ATOM 6950 O OG . SER B 1 153 ? -30.907 -4.466 -2.503 1.00 25.80 ? 173 SER B OG 1 ATOM 6951 N N . PHE B 1 154 ? -28.318 -5.969 -1.263 1.00 26.43 ? 174 PHE B N 1 ATOM 6952 C CA . PHE B 1 154 ? -26.940 -5.467 -1.194 1.00 27.29 ? 174 PHE B CA 1 ATOM 6953 C C . PHE B 1 154 ? -26.639 -4.407 -2.264 1.00 28.39 ? 174 PHE B C 1 ATOM 6954 O O . PHE B 1 154 ? -25.585 -3.752 -2.232 1.00 29.23 ? 174 PHE B O 1 ATOM 6955 C CB . PHE B 1 154 ? -25.947 -6.619 -1.364 1.00 27.41 ? 174 PHE B CB 1 ATOM 6956 C CG . PHE B 1 154 ? -25.779 -7.475 -0.137 1.00 27.00 ? 174 PHE B CG 1 ATOM 6957 C CD1 . PHE B 1 154 ? -25.176 -6.970 0.997 1.00 26.01 ? 174 PHE B CD1 1 ATOM 6958 C CD2 . PHE B 1 154 ? -26.212 -8.792 -0.128 1.00 27.64 ? 174 PHE B CD2 1 ATOM 6959 C CE1 . PHE B 1 154 ? -25.017 -7.761 2.124 1.00 26.48 ? 174 PHE B CE1 1 ATOM 6960 C CE2 . PHE B 1 154 ? -26.053 -9.587 0.997 1.00 27.17 ? 174 PHE B CE2 1 ATOM 6961 C CZ . PHE B 1 154 ? -25.451 -9.070 2.119 1.00 26.26 ? 174 PHE B CZ 1 ATOM 6962 N N . GLN B 1 155 ? -27.535 -4.242 -3.225 1.00 28.71 ? 175 GLN B N 1 ATOM 6963 C CA . GLN B 1 155 ? -27.250 -3.374 -4.359 1.00 29.21 ? 175 GLN B CA 1 ATOM 6964 C C . GLN B 1 155 ? -28.289 -2.288 -4.473 1.00 28.50 ? 175 GLN B C 1 ATOM 6965 O O . GLN B 1 155 ? -29.485 -2.563 -4.425 1.00 28.61 ? 175 GLN B O 1 ATOM 6966 C CB . GLN B 1 155 ? -27.194 -4.196 -5.639 1.00 29.75 ? 175 GLN B CB 1 ATOM 6967 C CG . GLN B 1 155 ? -26.024 -5.153 -5.655 1.00 32.22 ? 175 GLN B CG 1 ATOM 6968 C CD . GLN B 1 155 ? -26.108 -6.124 -6.786 1.00 35.70 ? 175 GLN B CD 1 ATOM 6969 O OE1 . GLN B 1 155 ? -27.087 -6.868 -6.907 1.00 39.02 ? 175 GLN B OE1 1 ATOM 6970 N NE2 . GLN B 1 155 ? -25.090 -6.132 -7.632 1.00 37.09 ? 175 GLN B NE2 1 ATOM 6971 N N . ASP B 1 156 ? -27.813 -1.055 -4.612 1.00 28.11 ? 176 ASP B N 1 ATOM 6972 C CA . ASP B 1 156 ? -28.661 0.123 -4.707 1.00 28.04 ? 176 ASP B CA 1 ATOM 6973 C C . ASP B 1 156 ? -29.719 0.066 -3.601 1.00 28.05 ? 176 ASP B C 1 ATOM 6974 O O . ASP B 1 156 ? -30.914 0.255 -3.842 1.00 27.72 ? 176 ASP B O 1 ATOM 6975 C CB . ASP B 1 156 ? -29.278 0.201 -6.103 1.00 27.71 ? 176 ASP B CB 1 ATOM 6976 C CG . ASP B 1 156 ? -28.222 0.139 -7.204 1.00 27.99 ? 176 ASP B CG 1 ATOM 6977 O OD1 . ASP B 1 156 ? -27.597 1.190 -7.512 1.00 26.01 ? 176 ASP B OD1 1 ATOM 6978 O OD2 . ASP B 1 156 ? -27.996 -0.969 -7.741 1.00 26.50 ? 176 ASP B OD2 1 ATOM 6979 N N . CYS B 1 157 ? -29.249 -0.194 -2.382 1.00 27.84 ? 177 CYS B N 1 ATOM 6980 C CA . CYS B 1 157 ? -30.131 -0.496 -1.260 1.00 28.05 ? 177 CYS B CA 1 ATOM 6981 C C . CYS B 1 157 ? -30.391 0.707 -0.350 1.00 28.50 ? 177 CYS B C 1 ATOM 6982 O O . CYS B 1 157 ? -31.469 0.830 0.231 1.00 29.02 ? 177 CYS B O 1 ATOM 6983 C CB . CYS B 1 157 ? -29.565 -1.677 -0.462 1.00 27.76 ? 177 CYS B CB 1 ATOM 6984 S SG . CYS B 1 157 ? -27.871 -1.469 0.104 1.00 27.43 ? 177 CYS B SG 1 ATOM 6985 N N . HIS B 1 158 ? -29.393 1.568 -0.204 1.00 28.94 ? 178 HIS B N 1 ATOM 6986 C CA . HIS B 1 158 ? -29.533 2.839 0.518 1.00 29.33 ? 178 HIS B CA 1 ATOM 6987 C C . HIS B 1 158 ? -30.029 2.700 1.972 1.00 29.70 ? 178 HIS B C 1 ATOM 6988 O O . HIS B 1 158 ? -29.227 2.399 2.860 1.00 29.92 ? 178 HIS B O 1 ATOM 6989 C CB . HIS B 1 158 ? -30.355 3.825 -0.333 1.00 29.36 ? 178 HIS B CB 1 ATOM 6990 C CG . HIS B 1 158 ? -29.795 4.005 -1.710 1.00 29.15 ? 178 HIS B CG 1 ATOM 6991 N ND1 . HIS B 1 158 ? -28.583 4.621 -1.941 1.00 29.01 ? 178 HIS B ND1 1 ATOM 6992 C CD2 . HIS B 1 158 ? -30.240 3.583 -2.917 1.00 29.57 ? 178 HIS B CD2 1 ATOM 6993 C CE1 . HIS B 1 158 ? -28.323 4.599 -3.236 1.00 29.36 ? 178 HIS B CE1 1 ATOM 6994 N NE2 . HIS B 1 158 ? -29.310 3.972 -3.850 1.00 29.48 ? 178 HIS B NE2 1 ATOM 6995 N N . ASP B 1 159 ? -31.318 2.912 2.222 1.00 29.91 ? 179 ASP B N 1 ATOM 6996 C CA . ASP B 1 159 ? -31.871 2.780 3.583 1.00 30.43 ? 179 ASP B CA 1 ATOM 6997 C C . ASP B 1 159 ? -32.400 1.364 3.878 1.00 29.76 ? 179 ASP B C 1 ATOM 6998 O O . ASP B 1 159 ? -32.899 1.098 4.975 1.00 29.94 ? 179 ASP B O 1 ATOM 6999 C CB . ASP B 1 159 ? -32.977 3.831 3.824 1.00 30.60 ? 179 ASP B CB 1 ATOM 7000 C CG . ASP B 1 159 ? -34.100 3.750 2.809 1.00 33.32 ? 179 ASP B CG 1 ATOM 7001 O OD1 . ASP B 1 159 ? -33.867 3.229 1.692 1.00 37.73 ? 179 ASP B OD1 1 ATOM 7002 O OD2 . ASP B 1 159 ? -35.225 4.213 3.110 1.00 37.67 ? 179 ASP B OD2 1 ATOM 7003 N N . ARG B 1 160 ? -32.292 0.463 2.899 1.00 29.16 ? 180 ARG B N 1 ATOM 7004 C CA . ARG B 1 160 ? -32.762 -0.914 3.034 1.00 28.38 ? 180 ARG B CA 1 ATOM 7005 C C . ARG B 1 160 ? -31.675 -1.898 2.611 1.00 27.42 ? 180 ARG B C 1 ATOM 7006 O O . ARG B 1 160 ? -31.831 -2.671 1.657 1.00 26.45 ? 180 ARG B O 1 ATOM 7007 C CB . ARG B 1 160 ? -34.026 -1.108 2.207 1.00 29.10 ? 180 ARG B CB 1 ATOM 7008 C CG . ARG B 1 160 ? -35.211 -0.305 2.714 1.00 31.12 ? 180 ARG B CG 1 ATOM 7009 C CD . ARG B 1 160 ? -36.463 -0.667 1.943 1.00 35.07 ? 180 ARG B CD 1 ATOM 7010 N NE . ARG B 1 160 ? -37.552 0.268 2.216 1.00 38.59 ? 180 ARG B NE 1 ATOM 7011 C CZ . ARG B 1 160 ? -38.511 0.095 3.130 1.00 41.97 ? 180 ARG B CZ 1 ATOM 7012 N NH1 . ARG B 1 160 ? -38.557 -0.997 3.896 1.00 42.92 ? 180 ARG B NH1 1 ATOM 7013 N NH2 . ARG B 1 160 ? -39.448 1.030 3.275 1.00 43.38 ? 180 ARG B NH2 1 ATOM 7014 N N . CYS B 1 161 ? -30.566 -1.869 3.343 1.00 26.33 ? 181 CYS B N 1 ATOM 7015 C CA . CYS B 1 161 ? -29.423 -2.694 3.019 1.00 25.79 ? 181 CYS B CA 1 ATOM 7016 C C . CYS B 1 161 ? -29.334 -3.896 3.938 1.00 25.12 ? 181 CYS B C 1 ATOM 7017 O O . CYS B 1 161 ? -29.589 -3.802 5.141 1.00 24.68 ? 181 CYS B O 1 ATOM 7018 C CB . CYS B 1 161 ? -28.134 -1.885 3.115 1.00 25.70 ? 181 CYS B CB 1 ATOM 7019 S SG . CYS B 1 161 ? -28.020 -0.530 1.916 1.00 27.69 ? 181 CYS B SG 1 ATOM 7020 N N . LEU B 1 162 ? -28.947 -5.025 3.362 1.00 24.23 ? 182 LEU B N 1 ATOM 7021 C CA . LEU B 1 162 ? -28.587 -6.190 4.145 1.00 23.80 ? 182 LEU B CA 1 ATOM 7022 C C . LEU B 1 162 ? -27.192 -5.981 4.728 1.00 23.52 ? 182 LEU B C 1 ATOM 7023 O O . LEU B 1 162 ? -26.383 -5.223 4.181 1.00 23.40 ? 182 LEU B O 1 ATOM 7024 C CB . LEU B 1 162 ? -28.611 -7.441 3.280 1.00 23.51 ? 182 LEU B CB 1 ATOM 7025 C CG . LEU B 1 162 ? -29.975 -7.822 2.708 1.00 23.63 ? 182 LEU B CG 1 ATOM 7026 C CD1 . LEU B 1 162 ? -29.827 -9.017 1.757 1.00 22.08 ? 182 LEU B CD1 1 ATOM 7027 C CD2 . LEU B 1 162 ? -30.989 -8.124 3.836 1.00 21.55 ? 182 LEU B CD2 1 ATOM 7028 N N . ALA B 1 163 ? -26.945 -6.626 5.862 1.00 22.76 ? 183 ALA B N 1 ATOM 7029 C CA . ALA B 1 163 ? -25.641 -6.635 6.497 1.00 22.40 ? 183 ALA B CA 1 ATOM 7030 C C . ALA B 1 163 ? -25.349 -8.069 6.910 1.00 22.31 ? 183 ALA B C 1 ATOM 7031 O O . ALA B 1 163 ? -26.212 -8.933 6.791 1.00 21.42 ? 183 ALA B O 1 ATOM 7032 C CB . ALA B 1 163 ? -25.646 -5.730 7.701 1.00 22.28 ? 183 ALA B CB 1 ATOM 7033 N N . PHE B 1 164 ? -24.137 -8.318 7.404 1.00 22.52 ? 184 PHE B N 1 ATOM 7034 C CA . PHE B 1 164 ? -23.794 -9.624 7.926 1.00 22.61 ? 184 PHE B CA 1 ATOM 7035 C C . PHE B 1 164 ? -23.037 -9.562 9.252 1.00 22.75 ? 184 PHE B C 1 ATOM 7036 O O . PHE B 1 164 ? -22.366 -8.570 9.552 1.00 23.54 ? 184 PHE B O 1 ATOM 7037 C CB . PHE B 1 164 ? -23.007 -10.431 6.888 1.00 22.93 ? 184 PHE B CB 1 ATOM 7038 C CG . PHE B 1 164 ? -21.604 -9.948 6.662 1.00 22.87 ? 184 PHE B CG 1 ATOM 7039 C CD1 . PHE B 1 164 ? -20.558 -10.439 7.438 1.00 24.19 ? 184 PHE B CD1 1 ATOM 7040 C CD2 . PHE B 1 164 ? -21.321 -9.027 5.671 1.00 23.15 ? 184 PHE B CD2 1 ATOM 7041 C CE1 . PHE B 1 164 ? -19.250 -10.017 7.225 1.00 24.00 ? 184 PHE B CE1 1 ATOM 7042 C CE2 . PHE B 1 164 ? -20.011 -8.589 5.454 1.00 24.02 ? 184 PHE B CE2 1 ATOM 7043 C CZ . PHE B 1 164 ? -18.977 -9.086 6.231 1.00 24.35 ? 184 PHE B CZ 1 ATOM 7044 N N . THR B 1 165 ? -23.171 -10.632 10.033 1.00 22.02 ? 185 THR B N 1 ATOM 7045 C CA . THR B 1 165 ? -22.412 -10.843 11.249 1.00 21.65 ? 185 THR B CA 1 ATOM 7046 C C . THR B 1 165 ? -21.615 -12.132 11.059 1.00 21.44 ? 185 THR B C 1 ATOM 7047 O O . THR B 1 165 ? -22.190 -13.209 10.839 1.00 21.21 ? 185 THR B O 1 ATOM 7048 C CB . THR B 1 165 ? -23.358 -10.993 12.461 1.00 22.07 ? 185 THR B CB 1 ATOM 7049 O OG1 . THR B 1 165 ? -24.028 -9.748 12.700 1.00 23.02 ? 185 THR B OG1 1 ATOM 7050 C CG2 . THR B 1 165 ? -22.602 -11.429 13.719 1.00 21.12 ? 185 THR B CG2 1 ATOM 7051 N N . ASP B 1 166 ? -20.294 -12.033 11.107 1.00 20.84 ? 186 ASP B N 1 ATOM 7052 C CA . ASP B 1 166 ? -19.488 -13.243 11.066 1.00 20.73 ? 186 ASP B CA 1 ATOM 7053 C C . ASP B 1 166 ? -19.421 -13.893 12.444 1.00 20.07 ? 186 ASP B C 1 ATOM 7054 O O . ASP B 1 166 ? -19.465 -13.206 13.485 1.00 20.92 ? 186 ASP B O 1 ATOM 7055 C CB . ASP B 1 166 ? -18.093 -12.989 10.489 1.00 21.09 ? 186 ASP B CB 1 ATOM 7056 C CG . ASP B 1 166 ? -17.301 -11.993 11.273 1.00 21.10 ? 186 ASP B CG 1 ATOM 7057 O OD1 . ASP B 1 166 ? -17.868 -10.951 11.667 1.00 23.65 ? 186 ASP B OD1 1 ATOM 7058 O OD2 . ASP B 1 166 ? -16.096 -12.239 11.458 1.00 20.66 ? 186 ASP B OD2 1 ATOM 7059 N N . VAL B 1 167 ? -19.367 -15.221 12.449 1.00 18.99 ? 187 VAL B N 1 ATOM 7060 C CA . VAL B 1 167 ? -19.094 -15.969 13.664 1.00 18.76 ? 187 VAL B CA 1 ATOM 7061 C C . VAL B 1 167 ? -17.695 -16.559 13.573 1.00 19.10 ? 187 VAL B C 1 ATOM 7062 O O . VAL B 1 167 ? -17.115 -16.646 12.503 1.00 18.79 ? 187 VAL B O 1 ATOM 7063 C CB . VAL B 1 167 ? -20.145 -17.080 13.951 1.00 18.37 ? 187 VAL B CB 1 ATOM 7064 C CG1 . VAL B 1 167 ? -21.551 -16.496 13.955 1.00 17.53 ? 187 VAL B CG1 1 ATOM 7065 C CG2 . VAL B 1 167 ? -20.039 -18.228 12.948 1.00 17.61 ? 187 VAL B CG2 1 ATOM 7066 N N . ALA B 1 168 ? -17.160 -16.931 14.726 1.00 19.67 ? 188 ALA B N 1 ATOM 7067 C CA . ALA B 1 168 ? -15.865 -17.562 14.824 1.00 19.93 ? 188 ALA B CA 1 ATOM 7068 C C . ALA B 1 168 ? -15.985 -18.650 15.885 1.00 20.44 ? 188 ALA B C 1 ATOM 7069 O O . ALA B 1 168 ? -16.854 -18.544 16.772 1.00 20.67 ? 188 ALA B O 1 ATOM 7070 C CB . ALA B 1 168 ? -14.811 -16.543 15.203 1.00 19.81 ? 188 ALA B CB 1 ATOM 7071 N N . PRO B 1 169 ? -15.112 -19.682 15.830 1.00 20.27 ? 189 PRO B N 1 ATOM 7072 C CA . PRO B 1 169 ? -13.996 -19.888 14.903 1.00 20.61 ? 189 PRO B CA 1 ATOM 7073 C C . PRO B 1 169 ? -14.427 -20.247 13.489 1.00 20.72 ? 189 PRO B C 1 ATOM 7074 O O . PRO B 1 169 ? -15.623 -20.461 13.229 1.00 20.32 ? 189 PRO B O 1 ATOM 7075 C CB . PRO B 1 169 ? -13.230 -21.055 15.540 1.00 20.69 ? 189 PRO B CB 1 ATOM 7076 C CG . PRO B 1 169 ? -14.263 -21.783 16.290 1.00 20.31 ? 189 PRO B CG 1 ATOM 7077 C CD . PRO B 1 169 ? -15.134 -20.729 16.862 1.00 19.88 ? 189 PRO B CD 1 ATOM 7078 N N . ARG B 1 170 ? -13.446 -20.320 12.589 1.00 21.03 ? 190 ARG B N 1 ATOM 7079 C CA . ARG B 1 170 ? -13.710 -20.215 11.150 1.00 21.14 ? 190 ARG B CA 1 ATOM 7080 C C . ARG B 1 170 ? -13.224 -21.442 10.407 1.00 21.28 ? 190 ARG B C 1 ATOM 7081 O O . ARG B 1 170 ? -12.227 -21.399 9.663 1.00 21.29 ? 190 ARG B O 1 ATOM 7082 C CB . ARG B 1 170 ? -13.043 -18.953 10.593 1.00 21.40 ? 190 ARG B CB 1 ATOM 7083 C CG . ARG B 1 170 ? -13.373 -17.707 11.366 1.00 21.56 ? 190 ARG B CG 1 ATOM 7084 C CD . ARG B 1 170 ? -12.437 -16.561 11.036 1.00 21.88 ? 190 ARG B CD 1 ATOM 7085 N NE . ARG B 1 170 ? -12.676 -15.458 11.958 1.00 21.04 ? 190 ARG B NE 1 ATOM 7086 C CZ . ARG B 1 170 ? -13.617 -14.530 11.810 1.00 21.00 ? 190 ARG B CZ 1 ATOM 7087 N NH1 . ARG B 1 170 ? -14.426 -14.533 10.754 1.00 20.51 ? 190 ARG B NH1 1 ATOM 7088 N NH2 . ARG B 1 170 ? -13.740 -13.581 12.728 1.00 20.02 ? 190 ARG B NH2 1 ATOM 7089 N N . GLY B 1 171 ? -13.945 -22.540 10.609 1.00 21.48 ? 191 GLY B N 1 ATOM 7090 C CA . GLY B 1 171 ? -13.588 -23.822 10.016 1.00 21.63 ? 191 GLY B CA 1 ATOM 7091 C C . GLY B 1 171 ? -13.690 -24.964 11.004 1.00 21.80 ? 191 GLY B C 1 ATOM 7092 O O . GLY B 1 171 ? -14.326 -24.836 12.052 1.00 22.23 ? 191 GLY B O 1 ATOM 7093 N N . VAL B 1 172 ? -13.079 -26.088 10.643 1.00 21.79 ? 192 VAL B N 1 ATOM 7094 C CA . VAL B 1 172 ? -13.118 -27.310 11.442 1.00 21.82 ? 192 VAL B CA 1 ATOM 7095 C C . VAL B 1 172 ? -11.728 -27.741 11.940 1.00 22.23 ? 192 VAL B C 1 ATOM 7096 O O . VAL B 1 172 ? -11.633 -28.681 12.723 1.00 22.53 ? 192 VAL B O 1 ATOM 7097 C CB . VAL B 1 172 ? -13.766 -28.477 10.646 1.00 21.89 ? 192 VAL B CB 1 ATOM 7098 C CG1 . VAL B 1 172 ? -15.220 -28.185 10.358 1.00 21.40 ? 192 VAL B CG1 1 ATOM 7099 C CG2 . VAL B 1 172 ? -13.010 -28.767 9.329 1.00 21.29 ? 192 VAL B CG2 1 ATOM 7100 N N . ALA B 1 173 ? -10.672 -27.039 11.520 1.00 22.15 ? 193 ALA B N 1 ATOM 7101 C CA . ALA B 1 173 ? -9.287 -27.406 11.852 1.00 22.51 ? 193 ALA B CA 1 ATOM 7102 C C . ALA B 1 173 ? -8.335 -26.215 11.802 1.00 22.68 ? 193 ALA B C 1 ATOM 7103 O O . ALA B 1 173 ? -8.613 -25.207 11.161 1.00 22.92 ? 193 ALA B O 1 ATOM 7104 C CB . ALA B 1 173 ? -8.786 -28.484 10.896 1.00 22.50 ? 193 ALA B CB 1 ATOM 7105 N N . SER B 1 174 ? -7.198 -26.360 12.474 1.00 23.01 ? 194 SER B N 1 ATOM 7106 C CA . SER B 1 174 ? -6.151 -25.343 12.500 1.00 23.10 ? 194 SER B CA 1 ATOM 7107 C C . SER B 1 174 ? -5.680 -25.048 11.085 1.00 23.06 ? 194 SER B C 1 ATOM 7108 O O . SER B 1 174 ? -5.409 -25.973 10.327 1.00 23.67 ? 194 SER B O 1 ATOM 7109 C CB . SER B 1 174 ? -4.966 -25.842 13.342 1.00 23.25 ? 194 SER B CB 1 ATOM 7110 O OG . SER B 1 174 ? -3.877 -24.929 13.295 1.00 23.86 ? 194 SER B OG 1 ATOM 7111 N N . GLY B 1 175 ? -5.618 -23.768 10.724 1.00 23.04 ? 195 GLY B N 1 ATOM 7112 C CA . GLY B 1 175 ? -5.155 -23.342 9.401 1.00 22.76 ? 195 GLY B CA 1 ATOM 7113 C C . GLY B 1 175 ? -6.279 -22.870 8.495 1.00 22.68 ? 195 GLY B C 1 ATOM 7114 O O . GLY B 1 175 ? -6.028 -22.238 7.475 1.00 22.30 ? 195 GLY B O 1 ATOM 7115 N N . GLN B 1 176 ? -7.524 -23.172 8.857 1.00 22.64 ? 196 GLN B N 1 ATOM 7116 C CA . GLN B 1 176 ? -8.670 -22.758 8.038 1.00 22.48 ? 196 GLN B CA 1 ATOM 7117 C C . GLN B 1 176 ? -9.108 -21.343 8.359 1.00 22.36 ? 196 GLN B C 1 ATOM 7118 O O . GLN B 1 176 ? -8.872 -20.837 9.459 1.00 22.98 ? 196 GLN B O 1 ATOM 7119 C CB . GLN B 1 176 ? -9.834 -23.747 8.181 1.00 22.51 ? 196 GLN B CB 1 ATOM 7120 C CG . GLN B 1 176 ? -9.426 -25.183 7.795 1.00 22.80 ? 196 GLN B CG 1 ATOM 7121 C CD . GLN B 1 176 ? -10.580 -26.167 7.716 1.00 23.87 ? 196 GLN B CD 1 ATOM 7122 O OE1 . GLN B 1 176 ? -11.736 -25.841 8.019 1.00 22.14 ? 196 GLN B OE1 1 ATOM 7123 N NE2 . GLN B 1 176 ? -10.271 -27.383 7.280 1.00 23.90 ? 196 GLN B NE2 1 ATOM 7124 N N . ARG B 1 177 ? -9.704 -20.695 7.366 1.00 21.97 ? 197 ARG B N 1 ATOM 7125 C CA . ARG B 1 177 ? -10.345 -19.402 7.536 1.00 21.85 ? 197 ARG B CA 1 ATOM 7126 C C . ARG B 1 177 ? -11.625 -19.399 6.704 1.00 21.57 ? 197 ARG B C 1 ATOM 7127 O O . ARG B 1 177 ? -11.703 -18.794 5.623 1.00 21.66 ? 197 ARG B O 1 ATOM 7128 C CB . ARG B 1 177 ? -9.394 -18.269 7.129 1.00 21.72 ? 197 ARG B CB 1 ATOM 7129 C CG . ARG B 1 177 ? -9.761 -16.918 7.709 1.00 21.35 ? 197 ARG B CG 1 ATOM 7130 C CD . ARG B 1 177 ? -8.619 -15.951 7.481 1.00 22.25 ? 197 ARG B CD 1 ATOM 7131 N NE . ARG B 1 177 ? -8.788 -14.630 8.085 1.00 21.72 ? 197 ARG B NE 1 ATOM 7132 C CZ . ARG B 1 177 ? -8.384 -14.289 9.307 1.00 20.57 ? 197 ARG B CZ 1 ATOM 7133 N NH1 . ARG B 1 177 ? -7.824 -15.177 10.120 1.00 21.24 ? 197 ARG B NH1 1 ATOM 7134 N NH2 . ARG B 1 177 ? -8.556 -13.043 9.727 1.00 21.00 ? 197 ARG B NH2 1 ATOM 7135 N N . ARG B 1 178 ? -12.614 -20.127 7.217 1.00 21.33 ? 198 ARG B N 1 ATOM 7136 C CA . ARG B 1 178 ? -13.880 -20.344 6.541 1.00 20.88 ? 198 ARG B CA 1 ATOM 7137 C C . ARG B 1 178 ? -14.987 -19.901 7.491 1.00 20.63 ? 198 ARG B C 1 ATOM 7138 O O . ARG B 1 178 ? -15.302 -20.610 8.445 1.00 20.39 ? 198 ARG B O 1 ATOM 7139 C CB . ARG B 1 178 ? -14.047 -21.826 6.197 1.00 21.16 ? 198 ARG B CB 1 ATOM 7140 C CG . ARG B 1 178 ? -12.923 -22.437 5.337 1.00 22.40 ? 198 ARG B CG 1 ATOM 7141 C CD . ARG B 1 178 ? -12.894 -23.966 5.459 1.00 23.70 ? 198 ARG B CD 1 ATOM 7142 N NE . ARG B 1 178 ? -14.038 -24.611 4.813 1.00 24.57 ? 198 ARG B NE 1 ATOM 7143 C CZ . ARG B 1 178 ? -14.501 -25.829 5.101 1.00 25.79 ? 198 ARG B CZ 1 ATOM 7144 N NH1 . ARG B 1 178 ? -13.941 -26.579 6.051 1.00 26.31 ? 198 ARG B NH1 1 ATOM 7145 N NH2 . ARG B 1 178 ? -15.547 -26.309 4.432 1.00 26.97 ? 198 ARG B NH2 1 ATOM 7146 N N . SER B 1 179 ? -15.570 -18.734 7.230 1.00 20.12 ? 199 SER B N 1 ATOM 7147 C CA . SER B 1 179 ? -16.497 -18.103 8.172 1.00 20.21 ? 199 SER B CA 1 ATOM 7148 C C . SER B 1 179 ? -17.960 -18.223 7.755 1.00 20.40 ? 199 SER B C 1 ATOM 7149 O O . SER B 1 179 ? -18.336 -17.908 6.615 1.00 19.80 ? 199 SER B O 1 ATOM 7150 C CB . SER B 1 179 ? -16.158 -16.616 8.331 1.00 20.23 ? 199 SER B CB 1 ATOM 7151 O OG . SER B 1 179 ? -14.821 -16.442 8.770 1.00 19.89 ? 199 SER B OG 1 ATOM 7152 N N . TRP B 1 180 ? -18.792 -18.654 8.697 1.00 20.60 ? 200 TRP B N 1 ATOM 7153 C CA . TRP B 1 180 ? -20.243 -18.543 8.529 1.00 20.59 ? 200 TRP B CA 1 ATOM 7154 C C . TRP B 1 180 ? -20.702 -17.128 8.822 1.00 20.41 ? 200 TRP B C 1 ATOM 7155 O O . TRP B 1 180 ? -20.306 -16.545 9.819 1.00 21.06 ? 200 TRP B O 1 ATOM 7156 C CB . TRP B 1 180 ? -20.971 -19.522 9.437 1.00 20.61 ? 200 TRP B CB 1 ATOM 7157 C CG . TRP B 1 180 ? -21.076 -20.894 8.861 1.00 21.04 ? 200 TRP B CG 1 ATOM 7158 C CD1 . TRP B 1 180 ? -20.411 -22.013 9.274 1.00 22.45 ? 200 TRP B CD1 1 ATOM 7159 C CD2 . TRP B 1 180 ? -21.916 -21.305 7.782 1.00 20.71 ? 200 TRP B CD2 1 ATOM 7160 N NE1 . TRP B 1 180 ? -20.787 -23.092 8.516 1.00 21.40 ? 200 TRP B NE1 1 ATOM 7161 C CE2 . TRP B 1 180 ? -21.710 -22.685 7.593 1.00 21.03 ? 200 TRP B CE2 1 ATOM 7162 C CE3 . TRP B 1 180 ? -22.825 -20.641 6.959 1.00 20.03 ? 200 TRP B CE3 1 ATOM 7163 C CZ2 . TRP B 1 180 ? -22.376 -23.411 6.610 1.00 21.42 ? 200 TRP B CZ2 1 ATOM 7164 C CZ3 . TRP B 1 180 ? -23.482 -21.360 5.988 1.00 20.77 ? 200 TRP B CZ3 1 ATOM 7165 C CH2 . TRP B 1 180 ? -23.255 -22.729 5.816 1.00 21.08 ? 200 TRP B CH2 1 ATOM 7166 N N . LEU B 1 181 ? -21.556 -16.596 7.956 1.00 20.55 ? 201 LEU B N 1 ATOM 7167 C CA . LEU B 1 181 ? -22.025 -15.226 8.037 1.00 20.47 ? 201 LEU B CA 1 ATOM 7168 C C . LEU B 1 181 ? -23.540 -15.240 8.183 1.00 20.35 ? 201 LEU B C 1 ATOM 7169 O O . LEU B 1 181 ? -24.232 -15.888 7.396 1.00 20.94 ? 201 LEU B O 1 ATOM 7170 C CB . LEU B 1 181 ? -21.624 -14.462 6.775 1.00 20.74 ? 201 LEU B CB 1 ATOM 7171 C CG . LEU B 1 181 ? -20.145 -14.564 6.362 1.00 20.92 ? 201 LEU B CG 1 ATOM 7172 C CD1 . LEU B 1 181 ? -19.902 -13.793 5.085 1.00 22.15 ? 201 LEU B CD1 1 ATOM 7173 C CD2 . LEU B 1 181 ? -19.219 -14.078 7.457 1.00 19.32 ? 201 LEU B CD2 1 ATOM 7174 N N . ILE B 1 182 ? -24.037 -14.566 9.215 1.00 19.75 ? 202 ILE B N 1 ATOM 7175 C CA . ILE B 1 182 ? -25.470 -14.425 9.457 1.00 19.47 ? 202 ILE B CA 1 ATOM 7176 C C . ILE B 1 182 ? -25.953 -13.173 8.737 1.00 19.51 ? 202 ILE B C 1 ATOM 7177 O O . ILE B 1 182 ? -25.509 -12.075 9.045 1.00 20.18 ? 202 ILE B O 1 ATOM 7178 C CB . ILE B 1 182 ? -25.788 -14.300 10.959 1.00 18.84 ? 202 ILE B CB 1 ATOM 7179 C CG1 . ILE B 1 182 ? -25.335 -15.545 11.720 1.00 18.79 ? 202 ILE B CG1 1 ATOM 7180 C CG2 . ILE B 1 182 ? -27.286 -14.122 11.188 1.00 19.18 ? 202 ILE B CG2 1 ATOM 7181 C CD1 . ILE B 1 182 ? -25.180 -15.314 13.239 1.00 17.63 ? 202 ILE B CD1 1 ATOM 7182 N N . ILE B 1 183 ? -26.860 -13.340 7.781 1.00 19.79 ? 203 ILE B N 1 ATOM 7183 C CA . ILE B 1 183 ? -27.375 -12.212 7.005 1.00 19.96 ? 203 ILE B CA 1 ATOM 7184 C C . ILE B 1 183 ? -28.509 -11.548 7.781 1.00 20.23 ? 203 ILE B C 1 ATOM 7185 O O . ILE B 1 183 ? -29.419 -12.218 8.287 1.00 19.85 ? 203 ILE B O 1 ATOM 7186 C CB . ILE B 1 183 ? -27.837 -12.646 5.602 1.00 20.10 ? 203 ILE B CB 1 ATOM 7187 C CG1 . ILE B 1 183 ? -26.706 -13.375 4.859 1.00 20.41 ? 203 ILE B CG1 1 ATOM 7188 C CG2 . ILE B 1 183 ? -28.270 -11.450 4.785 1.00 20.62 ? 203 ILE B CG2 1 ATOM 7189 C CD1 . ILE B 1 183 ? -25.387 -12.598 4.813 1.00 20.27 ? 203 ILE B CD1 1 ATOM 7190 N N . GLN B 1 184 ? -28.427 -10.226 7.887 1.00 20.68 ? 204 GLN B N 1 ATOM 7191 C CA . GLN B 1 184 ? -29.362 -9.432 8.692 1.00 21.25 ? 204 GLN B CA 1 ATOM 7192 C C . GLN B 1 184 ? -29.843 -8.220 7.903 1.00 21.42 ? 204 GLN B C 1 ATOM 7193 O O . GLN B 1 184 ? -29.164 -7.763 6.990 1.00 21.60 ? 204 GLN B O 1 ATOM 7194 C CB . GLN B 1 184 ? -28.668 -8.968 9.984 1.00 21.44 ? 204 GLN B CB 1 ATOM 7195 C CG . GLN B 1 184 ? -28.388 -10.097 10.985 1.00 22.24 ? 204 GLN B CG 1 ATOM 7196 C CD . GLN B 1 184 ? -27.058 -9.967 11.701 1.00 23.28 ? 204 GLN B CD 1 ATOM 7197 O OE1 . GLN B 1 184 ? -26.111 -9.364 11.192 1.00 25.41 ? 204 GLN B OE1 1 ATOM 7198 N NE2 . GLN B 1 184 ? -26.974 -10.556 12.885 1.00 23.52 ? 204 GLN B NE2 1 ATOM 7199 N N . ARG B 1 185 ? -31.020 -7.716 8.246 1.00 21.58 ? 205 ARG B N 1 ATOM 7200 C CA . ARG B 1 185 ? -31.453 -6.394 7.794 1.00 22.10 ? 205 ARG B CA 1 ATOM 7201 C C . ARG B 1 185 ? -30.748 -5.314 8.593 1.00 22.26 ? 205 ARG B C 1 ATOM 7202 O O . ARG B 1 185 ? -30.840 -5.297 9.821 1.00 21.88 ? 205 ARG B O 1 ATOM 7203 C CB . ARG B 1 185 ? -32.935 -6.197 8.027 1.00 21.86 ? 205 ARG B CB 1 ATOM 7204 C CG . ARG B 1 185 ? -33.824 -6.907 7.073 1.00 22.77 ? 205 ARG B CG 1 ATOM 7205 C CD . ARG B 1 185 ? -35.192 -6.999 7.706 1.00 23.95 ? 205 ARG B CD 1 ATOM 7206 N NE . ARG B 1 185 ? -36.245 -6.813 6.748 1.00 25.15 ? 205 ARG B NE 1 ATOM 7207 C CZ . ARG B 1 185 ? -37.535 -6.962 7.009 1.00 26.41 ? 205 ARG B CZ 1 ATOM 7208 N NH1 . ARG B 1 185 ? -37.962 -7.317 8.222 1.00 26.70 ? 205 ARG B NH1 1 ATOM 7209 N NH2 . ARG B 1 185 ? -38.404 -6.747 6.036 1.00 27.58 ? 205 ARG B NH2 1 ATOM 7210 N N . TYR B 1 186 ? -30.086 -4.392 7.902 1.00 22.53 ? 206 TYR B N 1 ATOM 7211 C CA . TYR B 1 186 ? -29.379 -3.310 8.590 1.00 23.31 ? 206 TYR B CA 1 ATOM 7212 C C . TYR B 1 186 ? -30.365 -2.205 8.987 1.00 22.61 ? 206 TYR B C 1 ATOM 7213 O O . TYR B 1 186 ? -30.616 -1.282 8.225 1.00 22.92 ? 206 TYR B O 1 ATOM 7214 C CB . TYR B 1 186 ? -28.243 -2.777 7.729 1.00 23.30 ? 206 TYR B CB 1 ATOM 7215 C CG . TYR B 1 186 ? -27.337 -1.808 8.440 1.00 26.75 ? 206 TYR B CG 1 ATOM 7216 C CD1 . TYR B 1 186 ? -26.683 -2.168 9.618 1.00 29.05 ? 206 TYR B CD1 1 ATOM 7217 C CD2 . TYR B 1 186 ? -27.125 -0.530 7.932 1.00 29.30 ? 206 TYR B CD2 1 ATOM 7218 C CE1 . TYR B 1 186 ? -25.849 -1.283 10.267 1.00 30.03 ? 206 TYR B CE1 1 ATOM 7219 C CE2 . TYR B 1 186 ? -26.292 0.363 8.575 1.00 30.63 ? 206 TYR B CE2 1 ATOM 7220 C CZ . TYR B 1 186 ? -25.658 -0.021 9.739 1.00 31.14 ? 206 TYR B CZ 1 ATOM 7221 O OH . TYR B 1 186 ? -24.829 0.871 10.370 1.00 33.09 ? 206 TYR B OH 1 ATOM 7222 N N . VAL B 1 187 ? -30.952 -2.358 10.172 1.00 21.88 ? 207 VAL B N 1 ATOM 7223 C CA . VAL B 1 187 ? -31.821 -1.351 10.786 1.00 21.12 ? 207 VAL B CA 1 ATOM 7224 C C . VAL B 1 187 ? -31.333 -1.093 12.204 1.00 21.09 ? 207 VAL B C 1 ATOM 7225 O O . VAL B 1 187 ? -30.379 -1.714 12.644 1.00 21.47 ? 207 VAL B O 1 ATOM 7226 C CB . VAL B 1 187 ? -33.298 -1.813 10.813 1.00 20.86 ? 207 VAL B CB 1 ATOM 7227 C CG1 . VAL B 1 187 ? -33.778 -2.078 9.397 1.00 19.59 ? 207 VAL B CG1 1 ATOM 7228 C CG2 . VAL B 1 187 ? -33.472 -3.063 11.691 1.00 19.57 ? 207 VAL B CG2 1 ATOM 7229 N N . GLU B 1 188 ? -31.980 -0.169 12.910 1.00 21.26 ? 208 GLU B N 1 ATOM 7230 C CA . GLU B 1 188 ? -31.673 0.103 14.314 1.00 21.33 ? 208 GLU B CA 1 ATOM 7231 C C . GLU B 1 188 ? -31.710 -1.205 15.103 1.00 20.95 ? 208 GLU B C 1 ATOM 7232 O O . GLU B 1 188 ? -32.726 -1.899 15.095 1.00 21.35 ? 208 GLU B O 1 ATOM 7233 C CB . GLU B 1 188 ? -32.689 1.097 14.894 1.00 21.38 ? 208 GLU B CB 1 ATOM 7234 C CG . GLU B 1 188 ? -32.313 1.656 16.261 1.00 22.03 ? 208 GLU B CG 1 ATOM 7235 C CD . GLU B 1 188 ? -33.480 2.350 16.944 1.00 21.96 ? 208 GLU B CD 1 ATOM 7236 O OE1 . GLU B 1 188 ? -34.513 2.546 16.286 1.00 23.52 ? 208 GLU B OE1 1 ATOM 7237 O OE2 . GLU B 1 188 ? -33.378 2.680 18.144 1.00 20.49 ? 208 GLU B OE2 1 ATOM 7238 N N . GLY B 1 189 ? -30.597 -1.545 15.758 1.00 20.64 ? 209 GLY B N 1 ATOM 7239 C CA . GLY B 1 189 ? -30.451 -2.826 16.465 1.00 20.01 ? 209 GLY B CA 1 ATOM 7240 C C . GLY B 1 189 ? -30.464 -4.034 15.532 1.00 19.81 ? 209 GLY B C 1 ATOM 7241 O O . GLY B 1 189 ? -31.075 -5.075 15.843 1.00 19.04 ? 209 GLY B O 1 ATOM 7242 N N . TYR B 1 190 ? -29.769 -3.884 14.398 1.00 19.36 ? 210 TYR B N 1 ATOM 7243 C CA . TYR B 1 190 ? -29.721 -4.884 13.316 1.00 19.22 ? 210 TYR B CA 1 ATOM 7244 C C . TYR B 1 190 ? -29.384 -6.312 13.755 1.00 18.80 ? 210 TYR B C 1 ATOM 7245 O O . TYR B 1 190 ? -29.736 -7.269 13.060 1.00 19.03 ? 210 TYR B O 1 ATOM 7246 C CB . TYR B 1 190 ? -28.729 -4.448 12.228 1.00 19.59 ? 210 TYR B CB 1 ATOM 7247 C CG . TYR B 1 190 ? -27.294 -4.265 12.693 1.00 20.97 ? 210 TYR B CG 1 ATOM 7248 C CD1 . TYR B 1 190 ? -26.375 -5.300 12.624 1.00 23.23 ? 210 TYR B CD1 1 ATOM 7249 C CD2 . TYR B 1 190 ? -26.860 -3.051 13.196 1.00 24.69 ? 210 TYR B CD2 1 ATOM 7250 C CE1 . TYR B 1 190 ? -25.049 -5.116 13.040 1.00 24.41 ? 210 TYR B CE1 1 ATOM 7251 C CE2 . TYR B 1 190 ? -25.545 -2.866 13.629 1.00 25.02 ? 210 TYR B CE2 1 ATOM 7252 C CZ . TYR B 1 190 ? -24.646 -3.899 13.544 1.00 25.21 ? 210 TYR B CZ 1 ATOM 7253 O OH . TYR B 1 190 ? -23.339 -3.688 13.975 1.00 27.44 ? 210 TYR B OH 1 ATOM 7254 N N . PHE B 1 191 ? -28.698 -6.442 14.891 1.00 18.35 ? 211 PHE B N 1 ATOM 7255 C CA . PHE B 1 191 ? -28.321 -7.743 15.465 1.00 17.89 ? 211 PHE B CA 1 ATOM 7256 C C . PHE B 1 191 ? -29.510 -8.705 15.627 1.00 17.63 ? 211 PHE B C 1 ATOM 7257 O O . PHE B 1 191 ? -29.321 -9.924 15.603 1.00 16.92 ? 211 PHE B O 1 ATOM 7258 C CB . PHE B 1 191 ? -27.683 -7.583 16.861 1.00 18.00 ? 211 PHE B CB 1 ATOM 7259 C CG . PHE B 1 191 ? -26.656 -6.495 16.963 1.00 18.08 ? 211 PHE B CG 1 ATOM 7260 C CD1 . PHE B 1 191 ? -26.960 -5.313 17.608 1.00 19.03 ? 211 PHE B CD1 1 ATOM 7261 C CD2 . PHE B 1 191 ? -25.385 -6.658 16.437 1.00 17.39 ? 211 PHE B CD2 1 ATOM 7262 C CE1 . PHE B 1 191 ? -26.010 -4.296 17.718 1.00 20.24 ? 211 PHE B CE1 1 ATOM 7263 C CE2 . PHE B 1 191 ? -24.433 -5.653 16.549 1.00 18.13 ? 211 PHE B CE2 1 ATOM 7264 C CZ . PHE B 1 191 ? -24.742 -4.470 17.189 1.00 18.20 ? 211 PHE B CZ 1 ATOM 7265 N N . LEU B 1 192 ? -30.709 -8.154 15.828 1.00 17.30 ? 212 LEU B N 1 ATOM 7266 C CA . LEU B 1 192 ? -31.913 -8.945 16.085 1.00 17.54 ? 212 LEU B CA 1 ATOM 7267 C C . LEU B 1 192 ? -32.789 -9.123 14.845 1.00 17.93 ? 212 LEU B C 1 ATOM 7268 O O . LEU B 1 192 ? -33.974 -9.492 14.951 1.00 17.72 ? 212 LEU B O 1 ATOM 7269 C CB . LEU B 1 192 ? -32.746 -8.289 17.185 1.00 17.70 ? 212 LEU B CB 1 ATOM 7270 C CG . LEU B 1 192 ? -32.028 -7.915 18.479 1.00 17.91 ? 212 LEU B CG 1 ATOM 7271 C CD1 . LEU B 1 192 ? -33.058 -7.398 19.516 1.00 18.11 ? 212 LEU B CD1 1 ATOM 7272 C CD2 . LEU B 1 192 ? -31.234 -9.103 19.014 1.00 16.56 ? 212 LEU B CD2 1 ATOM 7273 N N . HIS B 1 193 ? -32.209 -8.883 13.670 1.00 18.06 ? 213 HIS B N 1 ATOM 7274 C CA . HIS B 1 193 ? -32.966 -8.944 12.424 1.00 18.22 ? 213 HIS B CA 1 ATOM 7275 C C . HIS B 1 193 ? -32.381 -9.922 11.394 1.00 18.56 ? 213 HIS B C 1 ATOM 7276 O O . HIS B 1 193 ? -32.135 -9.543 10.255 1.00 18.51 ? 213 HIS B O 1 ATOM 7277 C CB . HIS B 1 193 ? -33.099 -7.532 11.844 1.00 18.06 ? 213 HIS B CB 1 ATOM 7278 C CG . HIS B 1 193 ? -33.961 -6.627 12.669 1.00 17.32 ? 213 HIS B CG 1 ATOM 7279 N ND1 . HIS B 1 193 ? -35.315 -6.490 12.452 1.00 18.64 ? 213 HIS B ND1 1 ATOM 7280 C CD2 . HIS B 1 193 ? -33.666 -5.829 13.723 1.00 16.79 ? 213 HIS B CD2 1 ATOM 7281 C CE1 . HIS B 1 193 ? -35.816 -5.641 13.335 1.00 17.81 ? 213 HIS B CE1 1 ATOM 7282 N NE2 . HIS B 1 193 ? -34.837 -5.232 14.120 1.00 16.99 ? 213 HIS B NE2 1 ATOM 7283 N N . PRO B 1 194 ? -32.184 -11.194 11.788 1.00 18.64 ? 214 PRO B N 1 ATOM 7284 C CA . PRO B 1 194 ? -31.727 -12.185 10.806 1.00 19.13 ? 214 PRO B CA 1 ATOM 7285 C C . PRO B 1 194 ? -32.772 -12.460 9.723 1.00 19.57 ? 214 PRO B C 1 ATOM 7286 O O . PRO B 1 194 ? -33.974 -12.439 10.008 1.00 19.80 ? 214 PRO B O 1 ATOM 7287 C CB . PRO B 1 194 ? -31.525 -13.440 11.651 1.00 18.97 ? 214 PRO B CB 1 ATOM 7288 C CG . PRO B 1 194 ? -32.515 -13.300 12.753 1.00 18.18 ? 214 PRO B CG 1 ATOM 7289 C CD . PRO B 1 194 ? -32.491 -11.823 13.083 1.00 18.54 ? 214 PRO B CD 1 ATOM 7290 N N . THR B 1 195 ? -32.317 -12.721 8.501 1.00 19.89 ? 215 THR B N 1 ATOM 7291 C CA . THR B 1 195 ? -33.223 -12.974 7.373 1.00 20.24 ? 215 THR B CA 1 ATOM 7292 C C . THR B 1 195 ? -33.551 -14.450 7.140 1.00 20.61 ? 215 THR B C 1 ATOM 7293 O O . THR B 1 195 ? -34.542 -14.764 6.476 1.00 20.93 ? 215 THR B O 1 ATOM 7294 C CB . THR B 1 195 ? -32.607 -12.454 6.077 1.00 20.29 ? 215 THR B CB 1 ATOM 7295 O OG1 . THR B 1 195 ? -31.373 -13.153 5.841 1.00 20.34 ? 215 THR B OG1 1 ATOM 7296 C CG2 . THR B 1 195 ? -32.350 -10.949 6.189 1.00 19.63 ? 215 THR B CG2 1 ATOM 7297 N N . GLY B 1 196 ? -32.709 -15.350 7.661 1.00 20.56 ? 216 GLY B N 1 ATOM 7298 C CA . GLY B 1 196 ? -32.854 -16.783 7.423 1.00 20.21 ? 216 GLY B CA 1 ATOM 7299 C C . GLY B 1 196 ? -31.780 -17.347 6.524 1.00 20.19 ? 216 GLY B C 1 ATOM 7300 O O . GLY B 1 196 ? -31.668 -18.565 6.377 1.00 20.04 ? 216 GLY B O 1 ATOM 7301 N N . LEU B 1 197 ? -30.995 -16.459 5.920 1.00 20.11 ? 217 LEU B N 1 ATOM 7302 C CA . LEU B 1 197 ? -29.872 -16.841 5.077 1.00 20.31 ? 217 LEU B CA 1 ATOM 7303 C C . LEU B 1 197 ? -28.581 -16.787 5.884 1.00 20.61 ? 217 LEU B C 1 ATOM 7304 O O . LEU B 1 197 ? -28.331 -15.812 6.599 1.00 20.98 ? 217 LEU B O 1 ATOM 7305 C CB . LEU B 1 197 ? -29.757 -15.884 3.885 1.00 20.28 ? 217 LEU B CB 1 ATOM 7306 C CG . LEU B 1 197 ? -28.696 -16.275 2.841 1.00 20.43 ? 217 LEU B CG 1 ATOM 7307 C CD1 . LEU B 1 197 ? -29.060 -17.593 2.163 1.00 21.55 ? 217 LEU B CD1 1 ATOM 7308 C CD2 . LEU B 1 197 ? -28.519 -15.180 1.815 1.00 18.41 ? 217 LEU B CD2 1 ATOM 7309 N N . GLU B 1 198 ? -27.778 -17.837 5.772 1.00 21.04 ? 218 GLU B N 1 ATOM 7310 C CA . GLU B 1 198 ? -26.397 -17.839 6.248 1.00 21.42 ? 218 GLU B CA 1 ATOM 7311 C C . GLU B 1 198 ? -25.496 -18.330 5.131 1.00 21.70 ? 218 GLU B C 1 ATOM 7312 O O . GLU B 1 198 ? -25.928 -19.119 4.295 1.00 21.31 ? 218 GLU B O 1 ATOM 7313 C CB . GLU B 1 198 ? -26.246 -18.737 7.479 1.00 21.41 ? 218 GLU B CB 1 ATOM 7314 C CG . GLU B 1 198 ? -27.208 -18.337 8.609 1.00 22.42 ? 218 GLU B CG 1 ATOM 7315 C CD . GLU B 1 198 ? -27.001 -19.126 9.881 1.00 22.64 ? 218 GLU B CD 1 ATOM 7316 O OE1 . GLU B 1 198 ? -26.295 -20.151 9.842 1.00 21.61 ? 218 GLU B OE1 1 ATOM 7317 O OE2 . GLU B 1 198 ? -27.545 -18.706 10.925 1.00 23.05 ? 218 GLU B OE2 1 ATOM 7318 N N . LEU B 1 199 ? -24.253 -17.853 5.126 1.00 21.91 ? 219 LEU B N 1 ATOM 7319 C CA . LEU B 1 199 ? -23.305 -18.122 4.047 1.00 22.59 ? 219 LEU B CA 1 ATOM 7320 C C . LEU B 1 199 ? -21.926 -18.478 4.596 1.00 22.29 ? 219 LEU B C 1 ATOM 7321 O O . LEU B 1 199 ? -21.408 -17.793 5.481 1.00 21.74 ? 219 LEU B O 1 ATOM 7322 C CB . LEU B 1 199 ? -23.158 -16.887 3.158 1.00 23.06 ? 219 LEU B CB 1 ATOM 7323 C CG . LEU B 1 199 ? -24.408 -16.416 2.411 1.00 24.68 ? 219 LEU B CG 1 ATOM 7324 C CD1 . LEU B 1 199 ? -24.201 -15.026 1.813 1.00 26.20 ? 219 LEU B CD1 1 ATOM 7325 C CD2 . LEU B 1 199 ? -24.758 -17.411 1.338 1.00 27.08 ? 219 LEU B CD2 1 ATOM 7326 N N . LEU B 1 200 ? -21.341 -19.546 4.065 1.00 22.08 ? 220 LEU B N 1 ATOM 7327 C CA . LEU B 1 200 ? -19.988 -19.938 4.416 1.00 22.24 ? 220 LEU B CA 1 ATOM 7328 C C . LEU B 1 200 ? -19.031 -19.441 3.346 1.00 22.47 ? 220 LEU B C 1 ATOM 7329 O O . LEU B 1 200 ? -19.175 -19.778 2.161 1.00 22.32 ? 220 LEU B O 1 ATOM 7330 C CB . LEU B 1 200 ? -19.886 -21.452 4.561 1.00 22.06 ? 220 LEU B CB 1 ATOM 7331 C CG . LEU B 1 200 ? -18.514 -22.020 4.933 1.00 22.29 ? 220 LEU B CG 1 ATOM 7332 C CD1 . LEU B 1 200 ? -17.993 -21.457 6.259 1.00 21.57 ? 220 LEU B CD1 1 ATOM 7333 C CD2 . LEU B 1 200 ? -18.587 -23.551 4.965 1.00 22.80 ? 220 LEU B CD2 1 ATOM 7334 N N . VAL B 1 201 ? -18.054 -18.645 3.769 1.00 22.75 ? 221 VAL B N 1 ATOM 7335 C CA . VAL B 1 201 ? -17.101 -18.023 2.857 1.00 22.75 ? 221 VAL B CA 1 ATOM 7336 C C . VAL B 1 201 ? -15.678 -18.457 3.189 1.00 22.95 ? 221 VAL B C 1 ATOM 7337 O O . VAL B 1 201 ? -15.236 -18.327 4.329 1.00 22.35 ? 221 VAL B O 1 ATOM 7338 C CB . VAL B 1 201 ? -17.201 -16.492 2.937 1.00 22.87 ? 221 VAL B CB 1 ATOM 7339 C CG1 . VAL B 1 201 ? -16.095 -15.826 2.112 1.00 23.50 ? 221 VAL B CG1 1 ATOM 7340 C CG2 . VAL B 1 201 ? -18.588 -16.012 2.482 1.00 22.96 ? 221 VAL B CG2 1 ATOM 7341 N N . ASP B 1 202 ? -14.966 -18.995 2.204 1.00 23.31 ? 222 ASP B N 1 ATOM 7342 C CA . ASP B 1 202 ? -13.550 -19.301 2.382 1.00 23.79 ? 222 ASP B CA 1 ATOM 7343 C C . ASP B 1 202 ? -12.769 -18.050 2.006 1.00 23.94 ? 222 ASP B C 1 ATOM 7344 O O . ASP B 1 202 ? -12.735 -17.674 0.839 1.00 24.37 ? 222 ASP B O 1 ATOM 7345 C CB . ASP B 1 202 ? -13.124 -20.487 1.509 1.00 24.05 ? 222 ASP B CB 1 ATOM 7346 C CG . ASP B 1 202 ? -11.677 -20.933 1.775 1.00 24.77 ? 222 ASP B CG 1 ATOM 7347 O OD1 . ASP B 1 202 ? -10.896 -20.181 2.394 1.00 25.36 ? 222 ASP B OD1 1 ATOM 7348 O OD2 . ASP B 1 202 ? -11.316 -22.055 1.370 1.00 27.69 ? 222 ASP B OD2 1 ATOM 7349 N N . HIS B 1 203 ? -12.167 -17.397 2.997 1.00 24.11 ? 223 HIS B N 1 ATOM 7350 C CA . HIS B 1 203 ? -11.393 -16.177 2.755 1.00 23.97 ? 223 HIS B CA 1 ATOM 7351 C C . HIS B 1 203 ? -9.957 -16.282 3.264 1.00 24.29 ? 223 HIS B C 1 ATOM 7352 O O . HIS B 1 203 ? -9.418 -15.331 3.799 1.00 24.31 ? 223 HIS B O 1 ATOM 7353 C CB . HIS B 1 203 ? -12.107 -14.928 3.307 1.00 23.91 ? 223 HIS B CB 1 ATOM 7354 C CG . HIS B 1 203 ? -12.444 -14.987 4.766 1.00 23.40 ? 223 HIS B CG 1 ATOM 7355 N ND1 . HIS B 1 203 ? -11.819 -14.192 5.706 1.00 22.96 ? 223 HIS B ND1 1 ATOM 7356 C CD2 . HIS B 1 203 ? -13.383 -15.696 5.437 1.00 22.82 ? 223 HIS B CD2 1 ATOM 7357 C CE1 . HIS B 1 203 ? -12.342 -14.432 6.898 1.00 23.04 ? 223 HIS B CE1 1 ATOM 7358 N NE2 . HIS B 1 203 ? -13.287 -15.345 6.763 1.00 22.71 ? 223 HIS B NE2 1 ATOM 7359 N N . GLY B 1 204 ? -9.334 -17.435 3.047 1.00 25.09 ? 224 GLY B N 1 ATOM 7360 C CA . GLY B 1 204 ? -7.977 -17.690 3.536 1.00 25.90 ? 224 GLY B CA 1 ATOM 7361 C C . GLY B 1 204 ? -6.860 -17.097 2.691 1.00 26.53 ? 224 GLY B C 1 ATOM 7362 O O . GLY B 1 204 ? -5.835 -16.658 3.217 1.00 26.53 ? 224 GLY B O 1 ATOM 7363 N N . SER B 1 205 ? -7.044 -17.098 1.376 1.00 27.33 ? 225 SER B N 1 ATOM 7364 C CA . SER B 1 205 ? -6.012 -16.595 0.465 1.00 27.82 ? 225 SER B CA 1 ATOM 7365 C C . SER B 1 205 ? -5.830 -15.096 0.633 1.00 27.80 ? 225 SER B C 1 ATOM 7366 O O . SER B 1 205 ? -6.793 -14.374 0.882 1.00 27.72 ? 225 SER B O 1 ATOM 7367 C CB . SER B 1 205 ? -6.385 -16.886 -0.987 1.00 27.93 ? 225 SER B CB 1 ATOM 7368 O OG . SER B 1 205 ? -5.543 -16.167 -1.868 1.00 29.01 ? 225 SER B OG 1 ATOM 7369 N N . THR B 1 206 ? -4.599 -14.634 0.463 1.00 27.76 ? 226 THR B N 1 ATOM 7370 C CA . THR B 1 206 ? -4.305 -13.206 0.457 1.00 28.23 ? 226 THR B CA 1 ATOM 7371 C C . THR B 1 206 ? -4.804 -12.502 -0.811 1.00 28.54 ? 226 THR B C 1 ATOM 7372 O O . THR B 1 206 ? -4.793 -11.274 -0.879 1.00 29.04 ? 226 THR B O 1 ATOM 7373 C CB . THR B 1 206 ? -2.799 -12.955 0.580 1.00 28.13 ? 226 THR B CB 1 ATOM 7374 O OG1 . THR B 1 206 ? -2.122 -13.610 -0.499 1.00 28.76 ? 226 THR B OG1 1 ATOM 7375 C CG2 . THR B 1 206 ? -2.284 -13.491 1.899 1.00 27.88 ? 226 THR B CG2 1 ATOM 7376 N N . ASP B 1 207 ? -5.214 -13.275 -1.816 1.00 28.71 ? 227 ASP B N 1 ATOM 7377 C CA . ASP B 1 207 ? -5.853 -12.731 -3.003 1.00 29.13 ? 227 ASP B CA 1 ATOM 7378 C C . ASP B 1 207 ? -7.364 -12.922 -2.856 1.00 29.03 ? 227 ASP B C 1 ATOM 7379 O O . ASP B 1 207 ? -7.887 -14.018 -3.031 1.00 28.78 ? 227 ASP B O 1 ATOM 7380 C CB . ASP B 1 207 ? -5.327 -13.432 -4.258 1.00 29.39 ? 227 ASP B CB 1 ATOM 7381 C CG . ASP B 1 207 ? -5.877 -12.830 -5.555 1.00 31.32 ? 227 ASP B CG 1 ATOM 7382 O OD1 . ASP B 1 207 ? -6.858 -12.055 -5.514 1.00 32.28 ? 227 ASP B OD1 1 ATOM 7383 O OD2 . ASP B 1 207 ? -5.318 -13.143 -6.629 1.00 34.22 ? 227 ASP B OD2 1 ATOM 7384 N N . ALA B 1 208 ? -8.056 -11.836 -2.540 1.00 29.21 ? 228 ALA B N 1 ATOM 7385 C CA . ALA B 1 208 ? -9.488 -11.873 -2.304 1.00 29.63 ? 228 ALA B CA 1 ATOM 7386 C C . ALA B 1 208 ? -10.221 -12.367 -3.540 1.00 30.10 ? 228 ALA B C 1 ATOM 7387 O O . ALA B 1 208 ? -11.360 -12.821 -3.449 1.00 29.82 ? 228 ALA B O 1 ATOM 7388 C CB . ALA B 1 208 ? -9.996 -10.504 -1.897 1.00 29.38 ? 228 ALA B CB 1 ATOM 7389 N N . GLY B 1 209 ? -9.556 -12.278 -4.690 1.00 30.48 ? 229 GLY B N 1 ATOM 7390 C CA . GLY B 1 209 ? -10.054 -12.871 -5.921 1.00 31.05 ? 229 GLY B CA 1 ATOM 7391 C C . GLY B 1 209 ? -10.373 -14.348 -5.817 1.00 31.30 ? 229 GLY B C 1 ATOM 7392 O O . GLY B 1 209 ? -11.278 -14.819 -6.489 1.00 31.84 ? 229 GLY B O 1 ATOM 7393 N N . HIS B 1 210 ? -9.641 -15.081 -4.977 1.00 31.58 ? 230 HIS B N 1 ATOM 7394 C CA . HIS B 1 210 ? -9.901 -16.506 -4.760 1.00 31.81 ? 230 HIS B CA 1 ATOM 7395 C C . HIS B 1 210 ? -11.053 -16.825 -3.796 1.00 31.24 ? 230 HIS B C 1 ATOM 7396 O O . HIS B 1 210 ? -11.454 -17.983 -3.692 1.00 31.40 ? 230 HIS B O 1 ATOM 7397 C CB . HIS B 1 210 ? -8.650 -17.203 -4.220 1.00 32.48 ? 230 HIS B CB 1 ATOM 7398 C CG . HIS B 1 210 ? -7.471 -17.144 -5.142 1.00 34.97 ? 230 HIS B CG 1 ATOM 7399 N ND1 . HIS B 1 210 ? -6.184 -16.941 -4.689 1.00 37.80 ? 230 HIS B ND1 1 ATOM 7400 C CD2 . HIS B 1 210 ? -7.382 -17.267 -6.488 1.00 36.79 ? 230 HIS B CD2 1 ATOM 7401 C CE1 . HIS B 1 210 ? -5.353 -16.943 -5.717 1.00 38.39 ? 230 HIS B CE1 1 ATOM 7402 N NE2 . HIS B 1 210 ? -6.054 -17.137 -6.819 1.00 38.24 ? 230 HIS B NE2 1 ATOM 7403 N N . TRP B 1 211 ? -11.567 -15.826 -3.078 1.00 30.39 ? 231 TRP B N 1 ATOM 7404 C CA . TRP B 1 211 ? -12.559 -16.073 -2.022 1.00 29.78 ? 231 TRP B CA 1 ATOM 7405 C C . TRP B 1 211 ? -13.877 -16.555 -2.614 1.00 29.54 ? 231 TRP B C 1 ATOM 7406 O O . TRP B 1 211 ? -14.303 -16.075 -3.658 1.00 29.73 ? 231 TRP B O 1 ATOM 7407 C CB . TRP B 1 211 ? -12.801 -14.811 -1.194 1.00 29.44 ? 231 TRP B CB 1 ATOM 7408 C CG . TRP B 1 211 ? -11.614 -14.370 -0.399 1.00 27.93 ? 231 TRP B CG 1 ATOM 7409 C CD1 . TRP B 1 211 ? -10.366 -14.925 -0.397 1.00 26.89 ? 231 TRP B CD1 1 ATOM 7410 C CD2 . TRP B 1 211 ? -11.556 -13.254 0.490 1.00 27.04 ? 231 TRP B CD2 1 ATOM 7411 N NE1 . TRP B 1 211 ? -9.546 -14.237 0.457 1.00 25.37 ? 231 TRP B NE1 1 ATOM 7412 C CE2 . TRP B 1 211 ? -10.250 -13.202 1.010 1.00 26.39 ? 231 TRP B CE2 1 ATOM 7413 C CE3 . TRP B 1 211 ? -12.485 -12.290 0.900 1.00 28.13 ? 231 TRP B CE3 1 ATOM 7414 C CZ2 . TRP B 1 211 ? -9.847 -12.222 1.918 1.00 27.06 ? 231 TRP B CZ2 1 ATOM 7415 C CZ3 . TRP B 1 211 ? -12.084 -11.319 1.810 1.00 27.14 ? 231 TRP B CZ3 1 ATOM 7416 C CH2 . TRP B 1 211 ? -10.783 -11.300 2.314 1.00 27.08 ? 231 TRP B CH2 1 ATOM 7417 N N . ALA B 1 212 ? -14.520 -17.499 -1.940 1.00 28.96 ? 232 ALA B N 1 ATOM 7418 C CA . ALA B 1 212 ? -15.728 -18.105 -2.485 1.00 28.57 ? 232 ALA B CA 1 ATOM 7419 C C . ALA B 1 212 ? -16.762 -18.392 -1.415 1.00 27.85 ? 232 ALA B C 1 ATOM 7420 O O . ALA B 1 212 ? -16.422 -18.759 -0.293 1.00 26.85 ? 232 ALA B O 1 ATOM 7421 C CB . ALA B 1 212 ? -15.373 -19.399 -3.230 1.00 28.43 ? 232 ALA B CB 1 ATOM 7422 N N . VAL B 1 213 ? -18.031 -18.234 -1.792 1.00 27.54 ? 233 VAL B N 1 ATOM 7423 C CA . VAL B 1 213 ? -19.138 -18.812 -1.043 1.00 27.14 ? 233 VAL B CA 1 ATOM 7424 C C . VAL B 1 213 ? -19.119 -20.308 -1.347 1.00 27.28 ? 233 VAL B C 1 ATOM 7425 O O . VAL B 1 213 ? -19.321 -20.703 -2.479 1.00 27.79 ? 233 VAL B O 1 ATOM 7426 C CB . VAL B 1 213 ? -20.491 -18.212 -1.464 1.00 27.12 ? 233 VAL B CB 1 ATOM 7427 C CG1 . VAL B 1 213 ? -21.655 -18.825 -0.651 1.00 26.53 ? 233 VAL B CG1 1 ATOM 7428 C CG2 . VAL B 1 213 ? -20.468 -16.692 -1.322 1.00 26.96 ? 233 VAL B CG2 1 ATOM 7429 N N . GLU B 1 214 ? -18.832 -21.137 -0.351 1.00 27.48 ? 234 GLU B N 1 ATOM 7430 C CA . GLU B 1 214 ? -18.743 -22.586 -0.573 1.00 27.73 ? 234 GLU B CA 1 ATOM 7431 C C . GLU B 1 214 ? -19.998 -23.323 -0.121 1.00 27.43 ? 234 GLU B C 1 ATOM 7432 O O . GLU B 1 214 ? -20.152 -24.510 -0.395 1.00 27.25 ? 234 GLU B O 1 ATOM 7433 C CB . GLU B 1 214 ? -17.510 -23.184 0.109 1.00 27.85 ? 234 GLU B CB 1 ATOM 7434 C CG . GLU B 1 214 ? -17.438 -23.006 1.617 1.00 28.77 ? 234 GLU B CG 1 ATOM 7435 C CD . GLU B 1 214 ? -16.274 -23.765 2.238 1.00 29.36 ? 234 GLU B CD 1 ATOM 7436 O OE1 . GLU B 1 214 ? -15.312 -23.123 2.716 1.00 29.37 ? 234 GLU B OE1 1 ATOM 7437 O OE2 . GLU B 1 214 ? -16.328 -25.013 2.259 1.00 29.50 ? 234 GLU B OE2 1 ATOM 7438 N N . GLN B 1 215 ? -20.888 -22.621 0.567 1.00 27.02 ? 235 GLN B N 1 ATOM 7439 C CA . GLN B 1 215 ? -22.094 -23.239 1.101 1.00 27.01 ? 235 GLN B CA 1 ATOM 7440 C C . GLN B 1 215 ? -23.088 -22.157 1.491 1.00 25.85 ? 235 GLN B C 1 ATOM 7441 O O . GLN B 1 215 ? -22.706 -21.052 1.861 1.00 24.91 ? 235 GLN B O 1 ATOM 7442 C CB . GLN B 1 215 ? -21.752 -24.135 2.308 1.00 27.45 ? 235 GLN B CB 1 ATOM 7443 C CG . GLN B 1 215 ? -22.897 -25.011 2.833 1.00 29.76 ? 235 GLN B CG 1 ATOM 7444 C CD . GLN B 1 215 ? -23.558 -25.866 1.757 1.00 32.26 ? 235 GLN B CD 1 ATOM 7445 O OE1 . GLN B 1 215 ? -24.426 -25.392 1.017 1.00 34.72 ? 235 GLN B OE1 1 ATOM 7446 N NE2 . GLN B 1 215 ? -23.172 -27.135 1.687 1.00 31.87 ? 235 GLN B NE2 1 ATOM 7447 N N . VAL B 1 216 ? -24.366 -22.493 1.397 1.00 25.17 ? 236 VAL B N 1 ATOM 7448 C CA . VAL B 1 216 ? -25.439 -21.551 1.662 1.00 24.81 ? 236 VAL B CA 1 ATOM 7449 C C . VAL B 1 216 ? -26.512 -22.262 2.470 1.00 24.27 ? 236 VAL B C 1 ATOM 7450 O O . VAL B 1 216 ? -26.850 -23.398 2.158 1.00 23.63 ? 236 VAL B O 1 ATOM 7451 C CB . VAL B 1 216 ? -26.040 -21.048 0.327 1.00 25.08 ? 236 VAL B CB 1 ATOM 7452 C CG1 . VAL B 1 216 ? -27.294 -20.230 0.569 1.00 24.62 ? 236 VAL B CG1 1 ATOM 7453 C CG2 . VAL B 1 216 ? -24.986 -20.260 -0.466 1.00 24.97 ? 236 VAL B CG2 1 ATOM 7454 N N . TRP B 1 217 ? -27.042 -21.592 3.497 1.00 23.65 ? 237 TRP B N 1 ATOM 7455 C CA . TRP B 1 217 ? -28.108 -22.144 4.329 1.00 23.18 ? 237 TRP B CA 1 ATOM 7456 C C . TRP B 1 217 ? -29.255 -21.163 4.353 1.00 22.98 ? 237 TRP B C 1 ATOM 7457 O O . TRP B 1 217 ? -29.064 -19.981 4.654 1.00 22.57 ? 237 TRP B O 1 ATOM 7458 C CB . TRP B 1 217 ? -27.611 -22.399 5.754 1.00 23.55 ? 237 TRP B CB 1 ATOM 7459 C CG . TRP B 1 217 ? -28.606 -23.048 6.697 1.00 23.65 ? 237 TRP B CG 1 ATOM 7460 C CD1 . TRP B 1 217 ? -28.749 -24.380 6.940 1.00 24.28 ? 237 TRP B CD1 1 ATOM 7461 C CD2 . TRP B 1 217 ? -29.570 -22.384 7.539 1.00 24.96 ? 237 TRP B CD2 1 ATOM 7462 N NE1 . TRP B 1 217 ? -29.744 -24.593 7.872 1.00 24.66 ? 237 TRP B NE1 1 ATOM 7463 C CE2 . TRP B 1 217 ? -30.258 -23.383 8.258 1.00 25.30 ? 237 TRP B CE2 1 ATOM 7464 C CE3 . TRP B 1 217 ? -29.920 -21.046 7.748 1.00 24.85 ? 237 TRP B CE3 1 ATOM 7465 C CZ2 . TRP B 1 217 ? -31.270 -23.082 9.178 1.00 25.61 ? 237 TRP B CZ2 1 ATOM 7466 C CZ3 . TRP B 1 217 ? -30.933 -20.749 8.655 1.00 24.33 ? 237 TRP B CZ3 1 ATOM 7467 C CH2 . TRP B 1 217 ? -31.598 -21.761 9.349 1.00 25.62 ? 237 TRP B CH2 1 ATOM 7468 N N . TYR B 1 218 ? -30.446 -21.647 4.012 1.00 22.59 ? 238 TYR B N 1 ATOM 7469 C CA . TYR B 1 218 ? -31.639 -20.821 4.076 1.00 22.55 ? 238 TYR B CA 1 ATOM 7470 C C . TYR B 1 218 ? -32.809 -21.574 4.693 1.00 22.68 ? 238 TYR B C 1 ATOM 7471 O O . TYR B 1 218 ? -33.204 -22.629 4.193 1.00 22.57 ? 238 TYR B O 1 ATOM 7472 C CB . TYR B 1 218 ? -32.043 -20.280 2.699 1.00 22.18 ? 238 TYR B CB 1 ATOM 7473 C CG . TYR B 1 218 ? -33.291 -19.458 2.820 1.00 21.67 ? 238 TYR B CG 1 ATOM 7474 C CD1 . TYR B 1 218 ? -33.252 -18.211 3.432 1.00 21.78 ? 238 TYR B CD1 1 ATOM 7475 C CD2 . TYR B 1 218 ? -34.528 -19.952 2.412 1.00 20.91 ? 238 TYR B CD2 1 ATOM 7476 C CE1 . TYR B 1 218 ? -34.397 -17.466 3.609 1.00 21.00 ? 238 TYR B CE1 1 ATOM 7477 C CE2 . TYR B 1 218 ? -35.683 -19.199 2.573 1.00 20.33 ? 238 TYR B CE2 1 ATOM 7478 C CZ . TYR B 1 218 ? -35.604 -17.953 3.178 1.00 20.38 ? 238 TYR B CZ 1 ATOM 7479 O OH . TYR B 1 218 ? -36.723 -17.180 3.373 1.00 19.25 ? 238 TYR B OH 1 ATOM 7480 N N . ASN B 1 219 ? -33.359 -21.020 5.774 1.00 22.93 ? 239 ASN B N 1 ATOM 7481 C CA . ASN B 1 219 ? -34.578 -21.537 6.386 1.00 23.44 ? 239 ASN B CA 1 ATOM 7482 C C . ASN B 1 219 ? -34.539 -23.054 6.526 1.00 24.13 ? 239 ASN B C 1 ATOM 7483 O O . ASN B 1 219 ? -35.441 -23.749 6.078 1.00 24.11 ? 239 ASN B O 1 ATOM 7484 C CB . ASN B 1 219 ? -35.808 -21.107 5.571 1.00 23.39 ? 239 ASN B CB 1 ATOM 7485 C CG . ASN B 1 219 ? -37.125 -21.310 6.329 1.00 23.77 ? 239 ASN B CG 1 ATOM 7486 O OD1 . ASN B 1 219 ? -37.156 -21.311 7.562 1.00 23.76 ? 239 ASN B OD1 1 ATOM 7487 N ND2 . ASN B 1 219 ? -38.218 -21.468 5.588 1.00 22.05 ? 239 ASN B ND2 1 ATOM 7488 N N . GLY B 1 220 ? -33.450 -23.558 7.104 1.00 24.76 ? 240 GLY B N 1 ATOM 7489 C CA . GLY B 1 220 ? -33.351 -24.970 7.474 1.00 25.10 ? 240 GLY B CA 1 ATOM 7490 C C . GLY B 1 220 ? -32.805 -25.929 6.430 1.00 25.53 ? 240 GLY B C 1 ATOM 7491 O O . GLY B 1 220 ? -32.729 -27.119 6.699 1.00 26.25 ? 240 GLY B O 1 ATOM 7492 N N . LYS B 1 221 ? -32.434 -25.441 5.245 1.00 26.06 ? 241 LYS B N 1 ATOM 7493 C CA . LYS B 1 221 ? -31.884 -26.300 4.184 1.00 26.47 ? 241 LYS B CA 1 ATOM 7494 C C . LYS B 1 221 ? -30.576 -25.733 3.653 1.00 25.91 ? 241 LYS B C 1 ATOM 7495 O O . LYS B 1 221 ? -30.413 -24.518 3.586 1.00 25.09 ? 241 LYS B O 1 ATOM 7496 C CB . LYS B 1 221 ? -32.856 -26.435 3.006 1.00 26.83 ? 241 LYS B CB 1 ATOM 7497 C CG . LYS B 1 221 ? -34.281 -26.835 3.367 1.00 29.28 ? 241 LYS B CG 1 ATOM 7498 C CD . LYS B 1 221 ? -34.367 -28.252 3.891 1.00 31.93 ? 241 LYS B CD 1 ATOM 7499 C CE . LYS B 1 221 ? -35.788 -28.594 4.320 1.00 33.01 ? 241 LYS B CE 1 ATOM 7500 N NZ . LYS B 1 221 ? -35.798 -29.857 5.089 1.00 34.41 ? 241 LYS B NZ 1 ATOM 7501 N N . PHE B 1 222 ? -29.661 -26.624 3.265 1.00 25.91 ? 242 PHE B N 1 ATOM 7502 C CA . PHE B 1 222 ? -28.432 -26.234 2.578 1.00 26.31 ? 242 PHE B CA 1 ATOM 7503 C C . PHE B 1 222 ? -28.647 -26.205 1.064 1.00 27.00 ? 242 PHE B C 1 ATOM 7504 O O . PHE B 1 222 ? -29.395 -27.028 0.528 1.00 27.35 ? 242 PHE B O 1 ATOM 7505 C CB . PHE B 1 222 ? -27.290 -27.182 2.927 1.00 26.03 ? 242 PHE B CB 1 ATOM 7506 C CG . PHE B 1 222 ? -26.904 -27.150 4.371 1.00 26.20 ? 242 PHE B CG 1 ATOM 7507 C CD1 . PHE B 1 222 ? -25.970 -26.227 4.831 1.00 26.17 ? 242 PHE B CD1 1 ATOM 7508 C CD2 . PHE B 1 222 ? -27.471 -28.038 5.279 1.00 25.58 ? 242 PHE B CD2 1 ATOM 7509 C CE1 . PHE B 1 222 ? -25.601 -26.196 6.162 1.00 26.51 ? 242 PHE B CE1 1 ATOM 7510 C CE2 . PHE B 1 222 ? -27.108 -28.011 6.619 1.00 25.41 ? 242 PHE B CE2 1 ATOM 7511 C CZ . PHE B 1 222 ? -26.168 -27.088 7.060 1.00 26.45 ? 242 PHE B CZ 1 ATOM 7512 N N . TYR B 1 223 ? -27.989 -25.266 0.383 1.00 27.45 ? 243 TYR B N 1 ATOM 7513 C CA . TYR B 1 223 ? -28.161 -25.096 -1.057 1.00 28.11 ? 243 TYR B CA 1 ATOM 7514 C C . TYR B 1 223 ? -26.885 -25.070 -1.892 1.00 29.01 ? 243 TYR B C 1 ATOM 7515 O O . TYR B 1 223 ? -26.980 -24.985 -3.117 1.00 30.42 ? 243 TYR B O 1 ATOM 7516 C CB . TYR B 1 223 ? -28.971 -23.837 -1.352 1.00 27.97 ? 243 TYR B CB 1 ATOM 7517 C CG . TYR B 1 223 ? -30.420 -23.964 -0.950 1.00 27.91 ? 243 TYR B CG 1 ATOM 7518 C CD1 . TYR B 1 223 ? -31.350 -24.547 -1.808 1.00 27.93 ? 243 TYR B CD1 1 ATOM 7519 C CD2 . TYR B 1 223 ? -30.859 -23.513 0.289 1.00 27.33 ? 243 TYR B CD2 1 ATOM 7520 C CE1 . TYR B 1 223 ? -32.680 -24.669 -1.445 1.00 28.02 ? 243 TYR B CE1 1 ATOM 7521 C CE2 . TYR B 1 223 ? -32.185 -23.626 0.663 1.00 27.84 ? 243 TYR B CE2 1 ATOM 7522 C CZ . TYR B 1 223 ? -33.090 -24.208 -0.203 1.00 27.45 ? 243 TYR B CZ 1 ATOM 7523 O OH . TYR B 1 223 ? -34.402 -24.313 0.160 1.00 27.24 ? 243 TYR B OH 1 ATOM 7524 N N . GLY B 1 224 ? -25.701 -25.101 -1.293 1.00 28.88 ? 244 GLY B N 1 ATOM 7525 C CA . GLY B 1 224 ? -24.492 -25.279 -2.109 1.00 28.96 ? 244 GLY B CA 1 ATOM 7526 C C . GLY B 1 224 ? -23.944 -24.020 -2.765 1.00 28.81 ? 244 GLY B C 1 ATOM 7527 O O . GLY B 1 224 ? -22.752 -23.754 -2.673 1.00 28.90 ? 244 GLY B O 1 ATOM 7528 N N . SER B 1 225 ? -24.795 -23.251 -3.443 1.00 28.23 ? 245 SER B N 1 ATOM 7529 C CA . SER B 1 225 ? -24.373 -21.955 -3.981 1.00 27.97 ? 245 SER B CA 1 ATOM 7530 C C . SER B 1 225 ? -25.538 -20.972 -4.073 1.00 27.71 ? 245 SER B C 1 ATOM 7531 O O . SER B 1 225 ? -26.700 -21.383 -4.095 1.00 27.91 ? 245 SER B O 1 ATOM 7532 C CB . SER B 1 225 ? -23.752 -22.136 -5.365 1.00 27.91 ? 245 SER B CB 1 ATOM 7533 O OG . SER B 1 225 ? -24.740 -22.504 -6.313 1.00 27.79 ? 245 SER B OG 1 ATOM 7534 N N . PRO B 1 226 ? -25.227 -19.667 -4.129 1.00 27.42 ? 246 PRO B N 1 ATOM 7535 C CA . PRO B 1 226 ? -26.238 -18.642 -4.358 1.00 27.16 ? 246 PRO B CA 1 ATOM 7536 C C . PRO B 1 226 ? -27.030 -18.862 -5.646 1.00 27.02 ? 246 PRO B C 1 ATOM 7537 O O . PRO B 1 226 ? -28.242 -18.632 -5.668 1.00 26.87 ? 246 PRO B O 1 ATOM 7538 C CB . PRO B 1 226 ? -25.415 -17.355 -4.443 1.00 27.18 ? 246 PRO B CB 1 ATOM 7539 C CG . PRO B 1 226 ? -24.187 -17.644 -3.646 1.00 27.48 ? 246 PRO B CG 1 ATOM 7540 C CD . PRO B 1 226 ? -23.900 -19.082 -3.855 1.00 27.38 ? 246 PRO B CD 1 ATOM 7541 N N . GLU B 1 227 ? -26.335 -19.292 -6.702 1.00 26.77 ? 247 GLU B N 1 ATOM 7542 C CA . GLU B 1 227 ? -26.966 -19.661 -7.968 1.00 26.41 ? 247 GLU B CA 1 ATOM 7543 C C . GLU B 1 227 ? -27.996 -20.769 -7.765 1.00 26.34 ? 247 GLU B C 1 ATOM 7544 O O . GLU B 1 227 ? -29.118 -20.666 -8.263 1.00 26.06 ? 247 GLU B O 1 ATOM 7545 C CB . GLU B 1 227 ? -25.909 -20.086 -9.004 1.00 26.34 ? 247 GLU B CB 1 ATOM 7546 N N . GLU B 1 228 ? -27.637 -21.813 -7.016 1.00 26.49 ? 248 GLU B N 1 ATOM 7547 C CA . GLU B 1 228 ? -28.570 -22.924 -6.791 1.00 26.91 ? 248 GLU B CA 1 ATOM 7548 C C . GLU B 1 228 ? -29.816 -22.473 -6.027 1.00 26.27 ? 248 GLU B C 1 ATOM 7549 O O . GLU B 1 228 ? -30.937 -22.815 -6.414 1.00 25.82 ? 248 GLU B O 1 ATOM 7550 C CB . GLU B 1 228 ? -27.916 -24.097 -6.060 1.00 27.30 ? 248 GLU B CB 1 ATOM 7551 C CG . GLU B 1 228 ? -28.839 -25.323 -5.962 1.00 29.82 ? 248 GLU B CG 1 ATOM 7552 C CD . GLU B 1 228 ? -28.295 -26.437 -5.067 1.00 33.59 ? 248 GLU B CD 1 ATOM 7553 O OE1 . GLU B 1 228 ? -27.089 -26.759 -5.176 1.00 36.70 ? 248 GLU B OE1 1 ATOM 7554 O OE2 . GLU B 1 228 ? -29.079 -26.994 -4.258 1.00 35.76 ? 248 GLU B OE2 1 ATOM 7555 N N . LEU B 1 229 ? -29.622 -21.718 -4.945 1.00 25.62 ? 249 LEU B N 1 ATOM 7556 C CA . LEU B 1 229 ? -30.763 -21.184 -4.193 1.00 25.39 ? 249 LEU B CA 1 ATOM 7557 C C . LEU B 1 229 ? -31.645 -20.302 -5.084 1.00 25.26 ? 249 LEU B C 1 ATOM 7558 O O . LEU B 1 229 ? -32.871 -20.374 -5.015 1.00 25.01 ? 249 LEU B O 1 ATOM 7559 C CB . LEU B 1 229 ? -30.304 -20.420 -2.941 1.00 24.92 ? 249 LEU B CB 1 ATOM 7560 C CG . LEU B 1 229 ? -31.402 -19.735 -2.107 1.00 24.65 ? 249 LEU B CG 1 ATOM 7561 C CD1 . LEU B 1 229 ? -32.529 -20.706 -1.752 1.00 23.77 ? 249 LEU B CD1 1 ATOM 7562 C CD2 . LEU B 1 229 ? -30.812 -19.089 -0.846 1.00 23.46 ? 249 LEU B CD2 1 ATOM 7563 N N . ALA B 1 230 ? -31.012 -19.489 -5.925 1.00 25.51 ? 250 ALA B N 1 ATOM 7564 C CA . ALA B 1 230 ? -31.726 -18.621 -6.867 1.00 25.70 ? 250 ALA B CA 1 ATOM 7565 C C . ALA B 1 230 ? -32.610 -19.421 -7.836 1.00 25.98 ? 250 ALA B C 1 ATOM 7566 O O . ALA B 1 230 ? -33.793 -19.105 -8.020 1.00 25.67 ? 250 ALA B O 1 ATOM 7567 C CB . ALA B 1 230 ? -30.730 -17.748 -7.639 1.00 25.50 ? 250 ALA B CB 1 ATOM 7568 N N . ARG B 1 231 ? -32.042 -20.468 -8.433 1.00 26.24 ? 251 ARG B N 1 ATOM 7569 C CA . ARG B 1 231 ? -32.769 -21.306 -9.387 1.00 26.32 ? 251 ARG B CA 1 ATOM 7570 C C . ARG B 1 231 ? -33.934 -22.044 -8.714 1.00 26.93 ? 251 ARG B C 1 ATOM 7571 O O . ARG B 1 231 ? -35.058 -22.065 -9.231 1.00 26.82 ? 251 ARG B O 1 ATOM 7572 C CB . ARG B 1 231 ? -31.821 -22.308 -10.054 1.00 26.41 ? 251 ARG B CB 1 ATOM 7573 N N . LYS B 1 232 ? -33.673 -22.628 -7.550 1.00 27.35 ? 252 LYS B N 1 ATOM 7574 C CA . LYS B 1 232 ? -34.721 -23.333 -6.821 1.00 27.86 ? 252 LYS B CA 1 ATOM 7575 C C . LYS B 1 232 ? -35.835 -22.400 -6.363 1.00 27.76 ? 252 LYS B C 1 ATOM 7576 O O . LYS B 1 232 ? -37.005 -22.782 -6.397 1.00 27.73 ? 252 LYS B O 1 ATOM 7577 C CB . LYS B 1 232 ? -34.145 -24.138 -5.662 1.00 27.99 ? 252 LYS B CB 1 ATOM 7578 C CG . LYS B 1 232 ? -33.496 -25.437 -6.139 1.00 29.84 ? 252 LYS B CG 1 ATOM 7579 C CD . LYS B 1 232 ? -33.166 -26.357 -4.993 1.00 32.16 ? 252 LYS B CD 1 ATOM 7580 C CE . LYS B 1 232 ? -32.380 -27.566 -5.456 1.00 34.17 ? 252 LYS B CE 1 ATOM 7581 N NZ . LYS B 1 232 ? -31.461 -28.040 -4.357 1.00 37.56 ? 252 LYS B NZ 1 ATOM 7582 N N . TYR B 1 233 ? -35.470 -21.181 -5.959 1.00 27.57 ? 253 TYR B N 1 ATOM 7583 C CA . TYR B 1 233 ? -36.458 -20.151 -5.658 1.00 27.45 ? 253 TYR B CA 1 ATOM 7584 C C . TYR B 1 233 ? -37.341 -19.876 -6.883 1.00 27.54 ? 253 TYR B C 1 ATOM 7585 O O . TYR B 1 233 ? -38.568 -19.965 -6.810 1.00 26.99 ? 253 TYR B O 1 ATOM 7586 C CB . TYR B 1 233 ? -35.776 -18.858 -5.200 1.00 27.37 ? 253 TYR B CB 1 ATOM 7587 C CG . TYR B 1 233 ? -36.746 -17.723 -5.002 1.00 27.62 ? 253 TYR B CG 1 ATOM 7588 C CD1 . TYR B 1 233 ? -37.749 -17.813 -4.043 1.00 27.55 ? 253 TYR B CD1 1 ATOM 7589 C CD2 . TYR B 1 233 ? -36.684 -16.574 -5.784 1.00 27.50 ? 253 TYR B CD2 1 ATOM 7590 C CE1 . TYR B 1 233 ? -38.652 -16.789 -3.853 1.00 28.14 ? 253 TYR B CE1 1 ATOM 7591 C CE2 . TYR B 1 233 ? -37.595 -15.535 -5.601 1.00 27.93 ? 253 TYR B CE2 1 ATOM 7592 C CZ . TYR B 1 233 ? -38.580 -15.660 -4.632 1.00 28.20 ? 253 TYR B CZ 1 ATOM 7593 O OH . TYR B 1 233 ? -39.488 -14.655 -4.416 1.00 28.58 ? 253 TYR B OH 1 ATOM 7594 N N . ALA B 1 234 ? -36.704 -19.553 -8.006 1.00 27.74 ? 254 ALA B N 1 ATOM 7595 C CA . ALA B 1 234 ? -37.419 -19.332 -9.271 1.00 28.09 ? 254 ALA B CA 1 ATOM 7596 C C . ALA B 1 234 ? -38.326 -20.510 -9.642 1.00 28.27 ? 254 ALA B C 1 ATOM 7597 O O . ALA B 1 234 ? -39.435 -20.317 -10.137 1.00 28.95 ? 254 ALA B O 1 ATOM 7598 C CB . ALA B 1 234 ? -36.433 -19.063 -10.398 1.00 27.56 ? 254 ALA B CB 1 ATOM 7599 N N . ASP B 1 235 ? -37.856 -21.728 -9.392 1.00 28.58 ? 255 ASP B N 1 ATOM 7600 C CA . ASP B 1 235 ? -38.600 -22.926 -9.767 1.00 28.63 ? 255 ASP B CA 1 ATOM 7601 C C . ASP B 1 235 ? -39.640 -23.353 -8.748 1.00 29.02 ? 255 ASP B C 1 ATOM 7602 O O . ASP B 1 235 ? -40.262 -24.397 -8.916 1.00 29.54 ? 255 ASP B O 1 ATOM 7603 C CB . ASP B 1 235 ? -37.635 -24.069 -10.064 1.00 28.30 ? 255 ASP B CB 1 ATOM 7604 C CG . ASP B 1 235 ? -36.791 -23.798 -11.289 1.00 27.77 ? 255 ASP B CG 1 ATOM 7605 O OD1 . ASP B 1 235 ? -37.124 -22.875 -12.061 1.00 26.59 ? 255 ASP B OD1 1 ATOM 7606 O OD2 . ASP B 1 235 ? -35.792 -24.508 -11.484 1.00 28.16 ? 255 ASP B OD2 1 ATOM 7607 N N . GLY B 1 236 ? -39.854 -22.545 -7.714 1.00 29.10 ? 256 GLY B N 1 ATOM 7608 C CA . GLY B 1 236 ? -40.885 -22.829 -6.724 1.00 29.29 ? 256 GLY B CA 1 ATOM 7609 C C . GLY B 1 236 ? -40.498 -23.947 -5.787 1.00 29.57 ? 256 GLY B C 1 ATOM 7610 O O . GLY B 1 236 ? -41.364 -24.628 -5.246 1.00 29.54 ? 256 GLY B O 1 ATOM 7611 N N . GLU B 1 237 ? -39.196 -24.136 -5.580 1.00 30.18 ? 257 GLU B N 1 ATOM 7612 C CA . GLU B 1 237 ? -38.701 -25.231 -4.747 1.00 30.71 ? 257 GLU B CA 1 ATOM 7613 C C . GLU B 1 237 ? -38.010 -24.751 -3.465 1.00 30.78 ? 257 GLU B C 1 ATOM 7614 O O . GLU B 1 237 ? -37.110 -25.420 -2.963 1.00 31.09 ? 257 GLU B O 1 ATOM 7615 C CB . GLU B 1 237 ? -37.723 -26.091 -5.548 1.00 30.88 ? 257 GLU B CB 1 ATOM 7616 C CG . GLU B 1 237 ? -38.338 -26.773 -6.738 1.00 32.78 ? 257 GLU B CG 1 ATOM 7617 C CD . GLU B 1 237 ? -37.396 -27.772 -7.368 1.00 33.88 ? 257 GLU B CD 1 ATOM 7618 O OE1 . GLU B 1 237 ? -36.373 -27.359 -7.946 1.00 36.52 ? 257 GLU B OE1 1 ATOM 7619 O OE2 . GLU B 1 237 ? -37.682 -28.978 -7.289 1.00 36.15 ? 257 GLU B OE2 1 ATOM 7620 N N . VAL B 1 238 ? -38.411 -23.596 -2.944 1.00 30.95 ? 258 VAL B N 1 ATOM 7621 C CA . VAL B 1 238 ? -37.864 -23.104 -1.683 1.00 30.77 ? 258 VAL B CA 1 ATOM 7622 C C . VAL B 1 238 ? -38.988 -22.689 -0.753 1.00 31.25 ? 258 VAL B C 1 ATOM 7623 O O . VAL B 1 238 ? -39.930 -22.021 -1.150 1.00 31.00 ? 258 VAL B O 1 ATOM 7624 C CB . VAL B 1 238 ? -36.899 -21.911 -1.885 1.00 30.96 ? 258 VAL B CB 1 ATOM 7625 C CG1 . VAL B 1 238 ? -36.411 -21.384 -0.533 1.00 29.39 ? 258 VAL B CG1 1 ATOM 7626 C CG2 . VAL B 1 238 ? -35.713 -22.316 -2.771 1.00 29.91 ? 258 VAL B CG2 1 ATOM 7627 N N . ASP B 1 239 ? -38.882 -23.115 0.494 1.00 32.23 ? 259 ASP B N 1 ATOM 7628 C CA . ASP B 1 239 ? -39.833 -22.743 1.518 1.00 32.97 ? 259 ASP B CA 1 ATOM 7629 C C . ASP B 1 239 ? -39.374 -21.401 2.068 1.00 32.76 ? 259 ASP B C 1 ATOM 7630 O O . ASP B 1 239 ? -38.454 -21.347 2.885 1.00 33.06 ? 259 ASP B O 1 ATOM 7631 C CB . ASP B 1 239 ? -39.837 -23.810 2.610 1.00 33.63 ? 259 ASP B CB 1 ATOM 7632 C CG . ASP B 1 239 ? -40.879 -23.557 3.666 1.00 35.32 ? 259 ASP B CG 1 ATOM 7633 O OD1 . ASP B 1 239 ? -41.884 -22.867 3.377 1.00 38.05 ? 259 ASP B OD1 1 ATOM 7634 O OD2 . ASP B 1 239 ? -40.690 -24.066 4.788 1.00 38.87 ? 259 ASP B OD2 1 ATOM 7635 N N . VAL B 1 240 ? -39.976 -20.320 1.579 1.00 32.34 ? 260 VAL B N 1 ATOM 7636 C CA . VAL B 1 240 ? -39.537 -18.988 1.945 1.00 32.10 ? 260 VAL B CA 1 ATOM 7637 C C . VAL B 1 240 ? -40.367 -18.422 3.088 1.00 31.60 ? 260 VAL B C 1 ATOM 7638 O O . VAL B 1 240 ? -41.559 -18.716 3.223 1.00 31.34 ? 260 VAL B O 1 ATOM 7639 C CB . VAL B 1 240 ? -39.582 -17.995 0.749 1.00 32.46 ? 260 VAL B CB 1 ATOM 7640 C CG1 . VAL B 1 240 ? -38.744 -18.519 -0.429 1.00 32.51 ? 260 VAL B CG1 1 ATOM 7641 C CG2 . VAL B 1 240 ? -41.012 -17.706 0.332 1.00 31.89 ? 260 VAL B CG2 1 ATOM 7642 N N . VAL B 1 241 ? -39.706 -17.626 3.922 1.00 30.89 ? 261 VAL B N 1 ATOM 7643 C CA . VAL B 1 241 ? -40.378 -16.813 4.903 1.00 30.24 ? 261 VAL B CA 1 ATOM 7644 C C . VAL B 1 241 ? -40.213 -15.379 4.425 1.00 29.95 ? 261 VAL B C 1 ATOM 7645 O O . VAL B 1 241 ? -39.094 -14.877 4.334 1.00 29.85 ? 261 VAL B O 1 ATOM 7646 C CB . VAL B 1 241 ? -39.775 -16.983 6.312 1.00 30.38 ? 261 VAL B CB 1 ATOM 7647 C CG1 . VAL B 1 241 ? -40.477 -16.050 7.308 1.00 29.70 ? 261 VAL B CG1 1 ATOM 7648 C CG2 . VAL B 1 241 ? -39.881 -18.431 6.767 1.00 29.88 ? 261 VAL B CG2 1 ATOM 7649 N N . VAL B 1 242 ? -41.330 -14.750 4.073 1.00 29.31 ? 262 VAL B N 1 ATOM 7650 C CA . VAL B 1 242 ? -41.354 -13.345 3.714 1.00 28.90 ? 262 VAL B CA 1 ATOM 7651 C C . VAL B 1 242 ? -41.406 -12.577 5.026 1.00 29.14 ? 262 VAL B C 1 ATOM 7652 O O . VAL B 1 242 ? -42.366 -12.712 5.776 1.00 28.96 ? 262 VAL B O 1 ATOM 7653 C CB . VAL B 1 242 ? -42.585 -13.021 2.834 1.00 28.91 ? 262 VAL B CB 1 ATOM 7654 C CG1 . VAL B 1 242 ? -42.664 -11.539 2.532 1.00 28.23 ? 262 VAL B CG1 1 ATOM 7655 C CG2 . VAL B 1 242 ? -42.543 -13.847 1.535 1.00 27.76 ? 262 VAL B CG2 1 ATOM 7656 N N . LEU B 1 243 ? -40.369 -11.790 5.307 1.00 29.36 ? 263 LEU B N 1 ATOM 7657 C CA . LEU B 1 243 ? -40.219 -11.119 6.604 1.00 29.56 ? 263 LEU B CA 1 ATOM 7658 C C . LEU B 1 243 ? -41.256 -10.016 6.806 1.00 29.71 ? 263 LEU B C 1 ATOM 7659 O O . LEU B 1 243 ? -41.570 -9.288 5.867 1.00 30.07 ? 263 LEU B O 1 ATOM 7660 C CB . LEU B 1 243 ? -38.814 -10.521 6.747 1.00 29.37 ? 263 LEU B CB 1 ATOM 7661 C CG . LEU B 1 243 ? -37.616 -11.471 6.670 1.00 29.14 ? 263 LEU B CG 1 ATOM 7662 C CD1 . LEU B 1 243 ? -36.333 -10.729 6.965 1.00 28.79 ? 263 LEU B CD1 1 ATOM 7663 C CD2 . LEU B 1 243 ? -37.769 -12.627 7.617 1.00 28.82 ? 263 LEU B CD2 1 ATOM 7664 N N . GLU B 1 258 ? -45.940 5.940 14.597 1.00 39.43 ? 278 GLU B N 1 ATOM 7665 C CA . GLU B 1 258 ? -45.125 4.746 14.366 1.00 38.96 ? 278 GLU B CA 1 ATOM 7666 C C . GLU B 1 258 ? -44.534 4.249 15.681 1.00 38.27 ? 278 GLU B C 1 ATOM 7667 O O . GLU B 1 258 ? -43.711 4.943 16.280 1.00 38.97 ? 278 GLU B O 1 ATOM 7668 C CB . GLU B 1 258 ? -43.994 5.055 13.381 1.00 39.11 ? 278 GLU B CB 1 ATOM 7669 N N . PRO B 1 259 ? -44.948 3.057 16.147 1.00 37.07 ? 279 PRO B N 1 ATOM 7670 C CA . PRO B 1 259 ? -44.326 2.498 17.349 1.00 36.07 ? 279 PRO B CA 1 ATOM 7671 C C . PRO B 1 259 ? -42.847 2.175 17.115 1.00 34.66 ? 279 PRO B C 1 ATOM 7672 O O . PRO B 1 259 ? -42.444 1.979 15.974 1.00 34.71 ? 279 PRO B O 1 ATOM 7673 C CB . PRO B 1 259 ? -45.109 1.209 17.579 1.00 36.32 ? 279 PRO B CB 1 ATOM 7674 C CG . PRO B 1 259 ? -45.588 0.833 16.238 1.00 37.04 ? 279 PRO B CG 1 ATOM 7675 C CD . PRO B 1 259 ? -45.915 2.119 15.557 1.00 37.40 ? 279 PRO B CD 1 ATOM 7676 N N . PRO B 1 260 ? -42.035 2.128 18.182 1.00 32.86 ? 280 PRO B N 1 ATOM 7677 C CA . PRO B 1 260 ? -40.623 1.832 17.911 1.00 31.61 ? 280 PRO B CA 1 ATOM 7678 C C . PRO B 1 260 ? -40.412 0.412 17.398 1.00 29.95 ? 280 PRO B C 1 ATOM 7679 O O . PRO B 1 260 ? -41.240 -0.460 17.616 1.00 29.79 ? 280 PRO B O 1 ATOM 7680 C CB . PRO B 1 260 ? -39.947 2.005 19.277 1.00 31.51 ? 280 PRO B CB 1 ATOM 7681 C CG . PRO B 1 260 ? -40.907 2.825 20.092 1.00 32.36 ? 280 PRO B CG 1 ATOM 7682 C CD . PRO B 1 260 ? -42.276 2.452 19.598 1.00 32.87 ? 280 PRO B CD 1 ATOM 7683 N N . LEU B 1 261 ? -39.297 0.200 16.717 1.00 28.25 ? 281 LEU B N 1 ATOM 7684 C CA . LEU B 1 261 ? -38.856 -1.136 16.365 1.00 26.86 ? 281 LEU B CA 1 ATOM 7685 C C . LEU B 1 261 ? -38.598 -1.914 17.662 1.00 24.90 ? 281 LEU B C 1 ATOM 7686 O O . LEU B 1 261 ? -38.123 -1.341 18.647 1.00 23.82 ? 281 LEU B O 1 ATOM 7687 C CB . LEU B 1 261 ? -37.567 -1.031 15.541 1.00 27.20 ? 281 LEU B CB 1 ATOM 7688 C CG . LEU B 1 261 ? -37.317 -2.014 14.413 1.00 28.22 ? 281 LEU B CG 1 ATOM 7689 C CD1 . LEU B 1 261 ? -38.533 -2.109 13.512 1.00 28.67 ? 281 LEU B CD1 1 ATOM 7690 C CD2 . LEU B 1 261 ? -36.082 -1.537 13.639 1.00 28.57 ? 281 LEU B CD2 1 ATOM 7691 N N . PHE B 1 262 ? -38.895 -3.209 17.668 1.00 23.03 ? 282 PHE B N 1 ATOM 7692 C CA . PHE B 1 262 ? -38.642 -4.034 18.859 1.00 22.04 ? 282 PHE B CA 1 ATOM 7693 C C . PHE B 1 262 ? -37.168 -4.031 19.275 1.00 21.26 ? 282 PHE B C 1 ATOM 7694 O O . PHE B 1 262 ? -36.870 -4.237 20.443 1.00 20.86 ? 282 PHE B O 1 ATOM 7695 C CB . PHE B 1 262 ? -39.149 -5.482 18.682 1.00 21.60 ? 282 PHE B CB 1 ATOM 7696 C CG . PHE B 1 262 ? -38.299 -6.335 17.767 1.00 21.22 ? 282 PHE B CG 1 ATOM 7697 C CD1 . PHE B 1 262 ? -37.179 -7.003 18.253 1.00 20.65 ? 282 PHE B CD1 1 ATOM 7698 C CD2 . PHE B 1 262 ? -38.637 -6.493 16.430 1.00 20.51 ? 282 PHE B CD2 1 ATOM 7699 C CE1 . PHE B 1 262 ? -36.402 -7.795 17.416 1.00 21.17 ? 282 PHE B CE1 1 ATOM 7700 C CE2 . PHE B 1 262 ? -37.864 -7.280 15.584 1.00 20.16 ? 282 PHE B CE2 1 ATOM 7701 C CZ . PHE B 1 262 ? -36.748 -7.928 16.075 1.00 21.15 ? 282 PHE B CZ 1 ATOM 7702 N N . SER B 1 263 ? -36.264 -3.783 18.322 1.00 20.90 ? 283 SER B N 1 ATOM 7703 C CA . SER B 1 263 ? -34.808 -3.779 18.577 1.00 20.82 ? 283 SER B CA 1 ATOM 7704 C C . SER B 1 263 ? -34.285 -2.423 19.068 1.00 21.00 ? 283 SER B C 1 ATOM 7705 O O . SER B 1 263 ? -33.074 -2.250 19.302 1.00 20.50 ? 283 SER B O 1 ATOM 7706 C CB . SER B 1 263 ? -34.063 -4.178 17.305 1.00 21.06 ? 283 SER B CB 1 ATOM 7707 O OG . SER B 1 263 ? -34.458 -3.375 16.202 1.00 20.19 ? 283 SER B OG 1 ATOM 7708 N N . SER B 1 264 ? -35.203 -1.467 19.200 1.00 21.03 ? 284 SER B N 1 ATOM 7709 C CA . SER B 1 264 ? -34.890 -0.128 19.667 1.00 21.30 ? 284 SER B CA 1 ATOM 7710 C C . SER B 1 264 ? -35.050 -0.015 21.172 1.00 21.57 ? 284 SER B C 1 ATOM 7711 O O . SER B 1 264 ? -35.894 -0.690 21.765 1.00 21.11 ? 284 SER B O 1 ATOM 7712 C CB . SER B 1 264 ? -35.818 0.891 19.002 1.00 21.36 ? 284 SER B CB 1 ATOM 7713 O OG . SER B 1 264 ? -35.524 2.192 19.482 1.00 22.39 ? 284 SER B OG 1 ATOM 7714 N N . HIS B 1 265 ? -34.258 0.876 21.767 1.00 22.27 ? 285 HIS B N 1 ATOM 7715 C CA . HIS B 1 265 ? -34.359 1.238 23.183 1.00 22.72 ? 285 HIS B CA 1 ATOM 7716 C C . HIS B 1 265 ? -35.478 2.254 23.483 1.00 23.43 ? 285 HIS B C 1 ATOM 7717 O O . HIS B 1 265 ? -35.788 2.525 24.652 1.00 22.96 ? 285 HIS B O 1 ATOM 7718 C CB . HIS B 1 265 ? -33.035 1.843 23.661 1.00 22.87 ? 285 HIS B CB 1 ATOM 7719 C CG . HIS B 1 265 ? -31.976 0.834 23.962 1.00 23.80 ? 285 HIS B CG 1 ATOM 7720 N ND1 . HIS B 1 265 ? -31.311 0.136 22.976 1.00 25.08 ? 285 HIS B ND1 1 ATOM 7721 C CD2 . HIS B 1 265 ? -31.429 0.438 25.135 1.00 24.75 ? 285 HIS B CD2 1 ATOM 7722 C CE1 . HIS B 1 265 ? -30.407 -0.651 23.530 1.00 24.38 ? 285 HIS B CE1 1 ATOM 7723 N NE2 . HIS B 1 265 ? -30.462 -0.494 24.839 1.00 24.43 ? 285 HIS B NE2 1 ATOM 7724 N N . LYS B 1 266 ? -36.072 2.830 22.441 1.00 24.10 ? 286 LYS B N 1 ATOM 7725 C CA . LYS B 1 266 ? -37.085 3.873 22.635 1.00 24.67 ? 286 LYS B CA 1 ATOM 7726 C C . LYS B 1 266 ? -38.256 3.396 23.513 1.00 24.19 ? 286 LYS B C 1 ATOM 7727 O O . LYS B 1 266 ? -38.722 2.275 23.371 1.00 23.73 ? 286 LYS B O 1 ATOM 7728 C CB . LYS B 1 266 ? -37.602 4.372 21.291 1.00 25.14 ? 286 LYS B CB 1 ATOM 7729 C CG . LYS B 1 266 ? -36.588 5.185 20.507 1.00 26.94 ? 286 LYS B CG 1 ATOM 7730 C CD . LYS B 1 266 ? -37.139 5.502 19.123 1.00 30.20 ? 286 LYS B CD 1 ATOM 7731 C CE . LYS B 1 266 ? -36.153 6.297 18.276 1.00 31.55 ? 286 LYS B CE 1 ATOM 7732 N NZ . LYS B 1 266 ? -36.741 6.597 16.935 1.00 32.70 ? 286 LYS B NZ 1 ATOM 7733 N N . PRO B 1 267 ? -38.706 4.240 24.454 1.00 24.28 ? 287 PRO B N 1 ATOM 7734 C CA . PRO B 1 267 ? -39.778 3.818 25.347 1.00 24.26 ? 287 PRO B CA 1 ATOM 7735 C C . PRO B 1 267 ? -41.095 3.480 24.652 1.00 24.19 ? 287 PRO B C 1 ATOM 7736 O O . PRO B 1 267 ? -41.481 4.130 23.684 1.00 23.88 ? 287 PRO B O 1 ATOM 7737 C CB . PRO B 1 267 ? -39.967 5.028 26.272 1.00 24.54 ? 287 PRO B CB 1 ATOM 7738 C CG . PRO B 1 267 ? -38.673 5.716 26.263 1.00 24.66 ? 287 PRO B CG 1 ATOM 7739 C CD . PRO B 1 267 ? -38.091 5.502 24.899 1.00 24.27 ? 287 PRO B CD 1 ATOM 7740 N N . ARG B 1 268 ? -41.744 2.426 25.133 1.00 24.39 ? 288 ARG B N 1 ATOM 7741 C CA . ARG B 1 268 ? -43.139 2.142 24.801 1.00 24.57 ? 288 ARG B CA 1 ATOM 7742 C C . ARG B 1 268 ? -43.767 1.389 25.957 1.00 24.84 ? 288 ARG B C 1 ATOM 7743 O O . ARG B 1 268 ? -43.064 0.905 26.854 1.00 24.34 ? 288 ARG B O 1 ATOM 7744 C CB . ARG B 1 268 ? -43.289 1.347 23.494 1.00 24.63 ? 288 ARG B CB 1 ATOM 7745 C CG . ARG B 1 268 ? -42.624 -0.043 23.458 1.00 24.81 ? 288 ARG B CG 1 ATOM 7746 C CD . ARG B 1 268 ? -41.186 0.041 23.017 1.00 23.10 ? 288 ARG B CD 1 ATOM 7747 N NE . ARG B 1 268 ? -40.576 -1.265 22.731 1.00 23.53 ? 288 ARG B NE 1 ATOM 7748 C CZ . ARG B 1 268 ? -39.309 -1.413 22.326 1.00 22.90 ? 288 ARG B CZ 1 ATOM 7749 N NH1 . ARG B 1 268 ? -38.537 -0.354 22.139 1.00 21.93 ? 288 ARG B NH1 1 ATOM 7750 N NH2 . ARG B 1 268 ? -38.811 -2.615 22.091 1.00 23.66 ? 288 ARG B NH2 1 ATOM 7751 N N . GLY B 1 269 ? -45.090 1.288 25.925 1.00 25.28 ? 289 GLY B N 1 ATOM 7752 C CA . GLY B 1 269 ? -45.837 0.692 27.023 1.00 25.86 ? 289 GLY B CA 1 ATOM 7753 C C . GLY B 1 269 ? -46.006 1.712 28.136 1.00 26.46 ? 289 GLY B C 1 ATOM 7754 O O . GLY B 1 269 ? -45.465 2.814 28.073 1.00 26.72 ? 289 GLY B O 1 ATOM 7755 N N . ASP B 1 270 ? -46.780 1.350 29.147 1.00 27.10 ? 290 ASP B N 1 ATOM 7756 C CA . ASP B 1 270 ? -47.070 2.249 30.267 1.00 27.48 ? 290 ASP B CA 1 ATOM 7757 C C . ASP B 1 270 ? -46.996 1.456 31.549 1.00 27.07 ? 290 ASP B C 1 ATOM 7758 O O . ASP B 1 270 ? -47.589 0.381 31.653 1.00 27.07 ? 290 ASP B O 1 ATOM 7759 C CB . ASP B 1 270 ? -48.482 2.829 30.137 1.00 27.97 ? 290 ASP B CB 1 ATOM 7760 C CG . ASP B 1 270 ? -48.662 3.643 28.871 1.00 29.81 ? 290 ASP B CG 1 ATOM 7761 O OD1 . ASP B 1 270 ? -47.949 4.657 28.706 1.00 31.20 ? 290 ASP B OD1 1 ATOM 7762 O OD2 . ASP B 1 270 ? -49.515 3.262 28.043 1.00 33.33 ? 290 ASP B OD2 1 ATOM 7763 N N . PHE B 1 271 ? -46.269 1.977 32.526 1.00 26.79 ? 291 PHE B N 1 ATOM 7764 C CA . PHE B 1 271 ? -46.341 1.429 33.865 1.00 26.44 ? 291 PHE B CA 1 ATOM 7765 C C . PHE B 1 271 ? -47.736 1.721 34.438 1.00 26.67 ? 291 PHE B C 1 ATOM 7766 O O . PHE B 1 271 ? -48.391 2.685 34.032 1.00 26.78 ? 291 PHE B O 1 ATOM 7767 C CB . PHE B 1 271 ? -45.280 2.053 34.759 1.00 26.24 ? 291 PHE B CB 1 ATOM 7768 C CG . PHE B 1 271 ? -43.874 1.610 34.454 1.00 25.61 ? 291 PHE B CG 1 ATOM 7769 C CD1 . PHE B 1 271 ? -43.581 0.279 34.182 1.00 24.84 ? 291 PHE B CD1 1 ATOM 7770 C CD2 . PHE B 1 271 ? -42.826 2.528 34.491 1.00 24.62 ? 291 PHE B CD2 1 ATOM 7771 C CE1 . PHE B 1 271 ? -42.274 -0.124 33.922 1.00 25.02 ? 291 PHE B CE1 1 ATOM 7772 C CE2 . PHE B 1 271 ? -41.516 2.125 34.240 1.00 24.47 ? 291 PHE B CE2 1 ATOM 7773 C CZ . PHE B 1 271 ? -41.242 0.798 33.954 1.00 24.42 ? 291 PHE B CZ 1 ATOM 7774 N N . PRO B 1 272 ? -48.208 0.882 35.364 1.00 26.84 ? 292 PRO B N 1 ATOM 7775 C CA . PRO B 1 272 ? -49.452 1.204 36.053 1.00 27.01 ? 292 PRO B CA 1 ATOM 7776 C C . PRO B 1 272 ? -49.354 2.498 36.862 1.00 27.02 ? 292 PRO B C 1 ATOM 7777 O O . PRO B 1 272 ? -50.343 3.198 36.992 1.00 26.29 ? 292 PRO B O 1 ATOM 7778 C CB . PRO B 1 272 ? -49.668 0.003 36.981 1.00 27.00 ? 292 PRO B CB 1 ATOM 7779 C CG . PRO B 1 272 ? -48.895 -1.090 36.388 1.00 26.85 ? 292 PRO B CG 1 ATOM 7780 C CD . PRO B 1 272 ? -47.727 -0.470 35.700 1.00 27.14 ? 292 PRO B CD 1 ATOM 7781 N N . SER B 1 273 ? -48.173 2.786 37.405 1.00 27.43 ? 293 SER B N 1 ATOM 7782 C CA . SER B 1 273 ? -47.898 4.052 38.084 1.00 27.95 ? 293 SER B CA 1 ATOM 7783 C C . SER B 1 273 ? -46.761 4.759 37.346 1.00 28.45 ? 293 SER B C 1 ATOM 7784 O O . SER B 1 273 ? -45.594 4.643 37.739 1.00 28.49 ? 293 SER B O 1 ATOM 7785 C CB . SER B 1 273 ? -47.493 3.813 39.540 1.00 27.94 ? 293 SER B CB 1 ATOM 7786 O OG . SER B 1 273 ? -48.401 2.948 40.193 1.00 28.65 ? 293 SER B OG 1 ATOM 7787 N N . PRO B 1 274 ? -47.095 5.498 36.274 1.00 28.89 ? 294 PRO B N 1 ATOM 7788 C CA . PRO B 1 274 ? -46.064 6.171 35.467 1.00 29.23 ? 294 PRO B CA 1 ATOM 7789 C C . PRO B 1 274 ? -45.141 7.086 36.290 1.00 29.69 ? 294 PRO B C 1 ATOM 7790 O O . PRO B 1 274 ? -45.574 7.680 37.285 1.00 29.76 ? 294 PRO B O 1 ATOM 7791 C CB . PRO B 1 274 ? -46.879 6.998 34.466 1.00 29.22 ? 294 PRO B CB 1 ATOM 7792 C CG . PRO B 1 274 ? -48.235 6.398 34.454 1.00 28.79 ? 294 PRO B CG 1 ATOM 7793 C CD . PRO B 1 274 ? -48.457 5.830 35.816 1.00 28.69 ? 294 PRO B CD 1 ATOM 7794 N N . ILE B 1 275 ? -43.879 7.167 35.878 1.00 30.06 ? 295 ILE B N 1 ATOM 7795 C CA . ILE B 1 275 ? -42.890 8.031 36.522 1.00 30.46 ? 295 ILE B CA 1 ATOM 7796 C C . ILE B 1 275 ? -42.477 9.132 35.538 1.00 30.90 ? 295 ILE B C 1 ATOM 7797 O O . ILE B 1 275 ? -42.030 8.853 34.423 1.00 31.00 ? 295 ILE B O 1 ATOM 7798 C CB . ILE B 1 275 ? -41.651 7.229 36.974 1.00 30.41 ? 295 ILE B CB 1 ATOM 7799 C CG1 . ILE B 1 275 ? -42.036 6.264 38.114 1.00 30.14 ? 295 ILE B CG1 1 ATOM 7800 C CG2 . ILE B 1 275 ? -40.540 8.177 37.416 1.00 29.60 ? 295 ILE B CG2 1 ATOM 7801 C CD1 . ILE B 1 275 ? -40.979 5.208 38.427 1.00 27.99 ? 295 ILE B CD1 1 ATOM 7802 N N . HIS B 1 276 ? -42.635 10.383 35.957 1.00 31.35 ? 296 HIS B N 1 ATOM 7803 C CA . HIS B 1 276 ? -42.405 11.518 35.070 1.00 31.68 ? 296 HIS B CA 1 ATOM 7804 C C . HIS B 1 276 ? -41.195 12.363 35.460 1.00 30.67 ? 296 HIS B C 1 ATOM 7805 O O . HIS B 1 276 ? -40.811 13.258 34.713 1.00 31.41 ? 296 HIS B O 1 ATOM 7806 C CB . HIS B 1 276 ? -43.643 12.417 35.048 1.00 32.44 ? 296 HIS B CB 1 ATOM 7807 C CG . HIS B 1 276 ? -44.937 11.680 34.875 1.00 34.72 ? 296 HIS B CG 1 ATOM 7808 N ND1 . HIS B 1 276 ? -45.334 11.144 33.668 1.00 38.18 ? 296 HIS B ND1 1 ATOM 7809 C CD2 . HIS B 1 276 ? -45.936 11.413 35.751 1.00 36.84 ? 296 HIS B CD2 1 ATOM 7810 C CE1 . HIS B 1 276 ? -46.520 10.574 33.808 1.00 38.55 ? 296 HIS B CE1 1 ATOM 7811 N NE2 . HIS B 1 276 ? -46.908 10.724 35.064 1.00 37.98 ? 296 HIS B NE2 1 ATOM 7812 N N . VAL B 1 277 ? -40.593 12.102 36.615 1.00 29.39 ? 297 VAL B N 1 ATOM 7813 C CA . VAL B 1 277 ? -39.479 12.926 37.078 1.00 28.11 ? 297 VAL B CA 1 ATOM 7814 C C . VAL B 1 277 ? -38.219 12.101 37.229 1.00 27.44 ? 297 VAL B C 1 ATOM 7815 O O . VAL B 1 277 ? -38.271 10.873 37.269 1.00 27.42 ? 297 VAL B O 1 ATOM 7816 C CB . VAL B 1 277 ? -39.803 13.641 38.408 1.00 27.89 ? 297 VAL B CB 1 ATOM 7817 C CG1 . VAL B 1 277 ? -41.116 14.415 38.291 1.00 28.17 ? 297 VAL B CG1 1 ATOM 7818 C CG2 . VAL B 1 277 ? -39.866 12.647 39.561 1.00 27.52 ? 297 VAL B CG2 1 ATOM 7819 N N . SER B 1 278 ? -37.088 12.792 37.309 1.00 26.96 ? 298 SER B N 1 ATOM 7820 C CA A SER B 1 278 ? -35.795 12.134 37.447 0.60 26.85 ? 298 SER B CA 1 ATOM 7821 C CA B SER B 1 278 ? -35.786 12.148 37.452 0.40 26.80 ? 298 SER B CA 1 ATOM 7822 C C . SER B 1 278 ? -35.606 11.590 38.863 1.00 26.60 ? 298 SER B C 1 ATOM 7823 O O . SER B 1 278 ? -36.148 12.126 39.832 1.00 26.48 ? 298 SER B O 1 ATOM 7824 C CB A SER B 1 278 ? -34.662 13.098 37.091 0.60 26.93 ? 298 SER B CB 1 ATOM 7825 C CB B SER B 1 278 ? -34.666 13.145 37.145 0.40 26.86 ? 298 SER B CB 1 ATOM 7826 O OG A SER B 1 278 ? -34.643 14.214 37.967 0.60 27.11 ? 298 SER B OG 1 ATOM 7827 O OG B SER B 1 278 ? -35.034 14.024 36.097 0.40 26.78 ? 298 SER B OG 1 ATOM 7828 N N . GLY B 1 279 ? -34.846 10.510 38.973 1.00 26.15 ? 299 GLY B N 1 ATOM 7829 C CA . GLY B 1 279 ? -34.593 9.867 40.255 1.00 25.64 ? 299 GLY B CA 1 ATOM 7830 C C . GLY B 1 279 ? -33.457 10.521 41.011 1.00 25.15 ? 299 GLY B C 1 ATOM 7831 O O . GLY B 1 279 ? -32.830 11.471 40.514 1.00 24.62 ? 299 GLY B O 1 ATOM 7832 N N . PRO B 1 280 ? -33.170 10.010 42.216 1.00 24.54 ? 300 PRO B N 1 ATOM 7833 C CA . PRO B 1 280 ? -32.121 10.585 43.027 1.00 24.53 ? 300 PRO B CA 1 ATOM 7834 C C . PRO B 1 280 ? -30.781 10.520 42.316 1.00 24.28 ? 300 PRO B C 1 ATOM 7835 O O . PRO B 1 280 ? -30.572 9.655 41.461 1.00 24.13 ? 300 PRO B O 1 ATOM 7836 C CB . PRO B 1 280 ? -32.108 9.711 44.292 1.00 24.29 ? 300 PRO B CB 1 ATOM 7837 C CG . PRO B 1 280 ? -33.285 8.875 44.238 1.00 24.93 ? 300 PRO B CG 1 ATOM 7838 C CD . PRO B 1 280 ? -33.747 8.806 42.830 1.00 25.11 ? 300 PRO B CD 1 ATOM 7839 N N . ARG B 1 281 ? -29.889 11.436 42.659 1.00 24.30 ? 301 ARG B N 1 ATOM 7840 C CA . ARG B 1 281 ? -28.563 11.431 42.068 1.00 25.17 ? 301 ARG B CA 1 ATOM 7841 C C . ARG B 1 281 ? -27.496 11.728 43.111 1.00 24.74 ? 301 ARG B C 1 ATOM 7842 O O . ARG B 1 281 ? -27.774 12.312 44.161 1.00 24.63 ? 301 ARG B O 1 ATOM 7843 C CB . ARG B 1 281 ? -28.493 12.405 40.876 1.00 25.68 ? 301 ARG B CB 1 ATOM 7844 C CG . ARG B 1 281 ? -28.364 13.868 41.241 1.00 27.87 ? 301 ARG B CG 1 ATOM 7845 C CD . ARG B 1 281 ? -27.870 14.742 40.068 1.00 30.34 ? 301 ARG B CD 1 ATOM 7846 N NE . ARG B 1 281 ? -27.409 16.033 40.576 1.00 31.52 ? 301 ARG B NE 1 ATOM 7847 C CZ . ARG B 1 281 ? -28.208 17.010 41.012 1.00 33.48 ? 301 ARG B CZ 1 ATOM 7848 N NH1 . ARG B 1 281 ? -29.534 16.867 40.980 1.00 33.31 ? 301 ARG B NH1 1 ATOM 7849 N NH2 . ARG B 1 281 ? -27.680 18.150 41.475 1.00 33.48 ? 301 ARG B NH2 1 ATOM 7850 N N . LEU B 1 282 ? -26.281 11.290 42.817 1.00 24.72 ? 302 LEU B N 1 ATOM 7851 C CA . LEU B 1 282 ? -25.115 11.594 43.642 1.00 24.92 ? 302 LEU B CA 1 ATOM 7852 C C . LEU B 1 282 ? -24.660 13.040 43.456 1.00 24.40 ? 302 LEU B C 1 ATOM 7853 O O . LEU B 1 282 ? -24.593 13.524 42.339 1.00 23.65 ? 302 LEU B O 1 ATOM 7854 C CB . LEU B 1 282 ? -23.938 10.697 43.265 1.00 25.12 ? 302 LEU B CB 1 ATOM 7855 C CG . LEU B 1 282 ? -23.722 9.415 44.043 1.00 26.69 ? 302 LEU B CG 1 ATOM 7856 C CD1 . LEU B 1 282 ? -24.944 8.551 43.965 1.00 26.07 ? 302 LEU B CD1 1 ATOM 7857 C CD2 . LEU B 1 282 ? -22.480 8.698 43.466 1.00 26.98 ? 302 LEU B CD2 1 ATOM 7858 N N . VAL B 1 283 ? -24.328 13.708 44.556 1.00 24.41 ? 303 VAL B N 1 ATOM 7859 C CA . VAL B 1 283 ? -23.637 14.997 44.497 1.00 24.30 ? 303 VAL B CA 1 ATOM 7860 C C . VAL B 1 283 ? -22.305 14.840 45.211 1.00 24.03 ? 303 VAL B C 1 ATOM 7861 O O . VAL B 1 283 ? -22.194 14.071 46.160 1.00 23.96 ? 303 VAL B O 1 ATOM 7862 C CB . VAL B 1 283 ? -24.460 16.147 45.111 1.00 24.38 ? 303 VAL B CB 1 ATOM 7863 C CG1 . VAL B 1 283 ? -25.749 16.307 44.358 1.00 24.79 ? 303 VAL B CG1 1 ATOM 7864 C CG2 . VAL B 1 283 ? -24.728 15.915 46.589 1.00 24.27 ? 303 VAL B CG2 1 ATOM 7865 N N . GLN B 1 284 ? -21.287 15.533 44.717 1.00 23.93 ? 304 GLN B N 1 ATOM 7866 C CA . GLN B 1 284 ? -19.956 15.476 45.304 1.00 23.93 ? 304 GLN B CA 1 ATOM 7867 C C . GLN B 1 284 ? -19.422 16.907 45.473 1.00 24.62 ? 304 GLN B C 1 ATOM 7868 O O . GLN B 1 284 ? -18.412 17.274 44.869 1.00 23.98 ? 304 GLN B O 1 ATOM 7869 C CB . GLN B 1 284 ? -19.026 14.635 44.416 1.00 23.74 ? 304 GLN B CB 1 ATOM 7870 C CG . GLN B 1 284 ? -17.675 14.273 45.063 1.00 22.49 ? 304 GLN B CG 1 ATOM 7871 C CD . GLN B 1 284 ? -16.830 13.363 44.197 1.00 20.27 ? 304 GLN B CD 1 ATOM 7872 O OE1 . GLN B 1 284 ? -16.621 12.201 44.527 1.00 19.57 ? 304 GLN B OE1 1 ATOM 7873 N NE2 . GLN B 1 284 ? -16.353 13.883 43.076 1.00 19.64 ? 304 GLN B NE2 1 ATOM 7874 N N . PRO B 1 285 ? -20.101 17.725 46.304 1.00 25.53 ? 305 PRO B N 1 ATOM 7875 C CA . PRO B 1 285 ? -19.682 19.131 46.464 1.00 26.03 ? 305 PRO B CA 1 ATOM 7876 C C . PRO B 1 285 ? -18.255 19.338 46.975 1.00 26.30 ? 305 PRO B C 1 ATOM 7877 O O . PRO B 1 285 ? -17.654 20.366 46.673 1.00 26.71 ? 305 PRO B O 1 ATOM 7878 C CB . PRO B 1 285 ? -20.699 19.711 47.472 1.00 26.06 ? 305 PRO B CB 1 ATOM 7879 C CG . PRO B 1 285 ? -21.403 18.547 48.071 1.00 25.89 ? 305 PRO B CG 1 ATOM 7880 C CD . PRO B 1 285 ? -21.319 17.421 47.076 1.00 25.71 ? 305 PRO B CD 1 ATOM 7881 N N . HIS B 1 286 ? -17.712 18.382 47.721 1.00 26.92 ? 306 HIS B N 1 ATOM 7882 C CA . HIS B 1 286 ? -16.378 18.538 48.301 1.00 27.44 ? 306 HIS B CA 1 ATOM 7883 C C . HIS B 1 286 ? -15.296 17.857 47.478 1.00 27.65 ? 306 HIS B C 1 ATOM 7884 O O . HIS B 1 286 ? -14.168 17.701 47.935 1.00 28.23 ? 306 HIS B O 1 ATOM 7885 C CB . HIS B 1 286 ? -16.386 18.038 49.730 1.00 27.99 ? 306 HIS B CB 1 ATOM 7886 C CG . HIS B 1 286 ? -17.504 18.611 50.537 1.00 29.80 ? 306 HIS B CG 1 ATOM 7887 N ND1 . HIS B 1 286 ? -17.678 19.969 50.696 1.00 32.38 ? 306 HIS B ND1 1 ATOM 7888 C CD2 . HIS B 1 286 ? -18.530 18.018 51.189 1.00 31.44 ? 306 HIS B CD2 1 ATOM 7889 C CE1 . HIS B 1 286 ? -18.758 20.189 51.425 1.00 33.11 ? 306 HIS B CE1 1 ATOM 7890 N NE2 . HIS B 1 286 ? -19.293 19.022 51.739 1.00 33.30 ? 306 HIS B NE2 1 ATOM 7891 N N . GLY B 1 287 ? -15.638 17.474 46.252 1.00 27.36 ? 307 GLY B N 1 ATOM 7892 C CA . GLY B 1 287 ? -14.683 16.898 45.332 1.00 26.91 ? 307 GLY B CA 1 ATOM 7893 C C . GLY B 1 287 ? -14.354 15.467 45.690 1.00 26.60 ? 307 GLY B C 1 ATOM 7894 O O . GLY B 1 287 ? -14.802 14.973 46.719 1.00 26.25 ? 307 GLY B O 1 ATOM 7895 N N . PRO B 1 288 ? -13.565 14.794 44.835 1.00 26.51 ? 308 PRO B N 1 ATOM 7896 C CA . PRO B 1 288 ? -13.157 13.399 45.047 1.00 26.47 ? 308 PRO B CA 1 ATOM 7897 C C . PRO B 1 288 ? -12.386 13.170 46.345 1.00 26.26 ? 308 PRO B C 1 ATOM 7898 O O . PRO B 1 288 ? -11.620 14.031 46.760 1.00 26.66 ? 308 PRO B O 1 ATOM 7899 C CB . PRO B 1 288 ? -12.239 13.120 43.856 1.00 26.46 ? 308 PRO B CB 1 ATOM 7900 C CG . PRO B 1 288 ? -12.659 14.094 42.802 1.00 26.72 ? 308 PRO B CG 1 ATOM 7901 C CD . PRO B 1 288 ? -13.104 15.316 43.535 1.00 26.43 ? 308 PRO B CD 1 ATOM 7902 N N . ARG B 1 289 ? -12.580 12.005 46.960 1.00 26.03 ? 309 ARG B N 1 ATOM 7903 C CA . ARG B 1 289 ? -11.873 11.642 48.191 1.00 25.66 ? 309 ARG B CA 1 ATOM 7904 C C . ARG B 1 289 ? -10.732 10.690 47.888 1.00 25.73 ? 309 ARG B C 1 ATOM 7905 O O . ARG B 1 289 ? -9.976 10.318 48.772 1.00 26.28 ? 309 ARG B O 1 ATOM 7906 C CB . ARG B 1 289 ? -12.840 11.027 49.207 1.00 25.40 ? 309 ARG B CB 1 ATOM 7907 C CG . ARG B 1 289 ? -14.044 11.921 49.485 1.00 24.51 ? 309 ARG B CG 1 ATOM 7908 C CD . ARG B 1 289 ? -14.639 11.668 50.848 1.00 24.12 ? 309 ARG B CD 1 ATOM 7909 N NE . ARG B 1 289 ? -15.163 10.315 51.000 1.00 24.55 ? 309 ARG B NE 1 ATOM 7910 C CZ . ARG B 1 289 ? -15.584 9.793 52.151 1.00 24.49 ? 309 ARG B CZ 1 ATOM 7911 N NH1 . ARG B 1 289 ? -15.538 10.503 53.274 1.00 24.15 ? 309 ARG B NH1 1 ATOM 7912 N NH2 . ARG B 1 289 ? -16.053 8.548 52.184 1.00 24.45 ? 309 ARG B NH2 1 ATOM 7913 N N . PHE B 1 290 ? -10.607 10.313 46.623 1.00 25.71 ? 310 PHE B N 1 ATOM 7914 C CA . PHE B 1 290 ? -9.448 9.572 46.143 1.00 25.22 ? 310 PHE B CA 1 ATOM 7915 C C . PHE B 1 290 ? -8.531 10.553 45.427 1.00 25.35 ? 310 PHE B C 1 ATOM 7916 O O . PHE B 1 290 ? -8.971 11.610 44.980 1.00 25.27 ? 310 PHE B O 1 ATOM 7917 C CB . PHE B 1 290 ? -9.885 8.442 45.193 1.00 25.18 ? 310 PHE B CB 1 ATOM 7918 C CG . PHE B 1 290 ? -10.780 8.902 44.076 1.00 23.91 ? 310 PHE B CG 1 ATOM 7919 C CD1 . PHE B 1 290 ? -10.248 9.278 42.855 1.00 23.50 ? 310 PHE B CD1 1 ATOM 7920 C CD2 . PHE B 1 290 ? -12.152 8.983 44.262 1.00 23.18 ? 310 PHE B CD2 1 ATOM 7921 C CE1 . PHE B 1 290 ? -11.070 9.718 41.832 1.00 23.88 ? 310 PHE B CE1 1 ATOM 7922 C CE2 . PHE B 1 290 ? -12.985 9.417 43.247 1.00 23.39 ? 310 PHE B CE2 1 ATOM 7923 C CZ . PHE B 1 290 ? -12.441 9.789 42.026 1.00 24.11 ? 310 PHE B CZ 1 ATOM 7924 N N . ARG B 1 291 ? -7.254 10.211 45.336 1.00 25.77 ? 311 ARG B N 1 ATOM 7925 C CA . ARG B 1 291 ? -6.282 11.023 44.606 1.00 26.13 ? 311 ARG B CA 1 ATOM 7926 C C . ARG B 1 291 ? -5.861 10.254 43.369 1.00 26.32 ? 311 ARG B C 1 ATOM 7927 O O . ARG B 1 291 ? -5.476 9.091 43.463 1.00 26.10 ? 311 ARG B O 1 ATOM 7928 C CB . ARG B 1 291 ? -5.057 11.321 45.480 1.00 25.99 ? 311 ARG B CB 1 ATOM 7929 N N . LEU B 1 292 ? -5.960 10.899 42.212 1.00 26.84 ? 312 LEU B N 1 ATOM 7930 C CA . LEU B 1 292 ? -5.545 10.303 40.949 1.00 27.16 ? 312 LEU B CA 1 ATOM 7931 C C . LEU B 1 292 ? -4.410 11.148 40.423 1.00 27.46 ? 312 LEU B C 1 ATOM 7932 O O . LEU B 1 292 ? -4.599 12.330 40.166 1.00 27.80 ? 312 LEU B O 1 ATOM 7933 C CB . LEU B 1 292 ? -6.698 10.301 39.943 1.00 26.99 ? 312 LEU B CB 1 ATOM 7934 C CG . LEU B 1 292 ? -6.419 9.811 38.515 1.00 27.02 ? 312 LEU B CG 1 ATOM 7935 C CD1 . LEU B 1 292 ? -6.084 8.324 38.475 1.00 26.60 ? 312 LEU B CD1 1 ATOM 7936 C CD2 . LEU B 1 292 ? -7.623 10.095 37.638 1.00 27.32 ? 312 LEU B CD2 1 ATOM 7937 N N . GLU B 1 293 ? -3.233 10.546 40.295 1.00 27.73 ? 313 GLU B N 1 ATOM 7938 C CA . GLU B 1 293 ? -2.092 11.190 39.655 1.00 28.02 ? 313 GLU B CA 1 ATOM 7939 C C . GLU B 1 293 ? -1.592 10.244 38.577 1.00 27.97 ? 313 GLU B C 1 ATOM 7940 O O . GLU B 1 293 ? -0.987 9.223 38.879 1.00 28.18 ? 313 GLU B O 1 ATOM 7941 C CB . GLU B 1 293 ? -0.985 11.480 40.672 1.00 27.85 ? 313 GLU B CB 1 ATOM 7942 N N . GLY B 1 294 ? -1.877 10.581 37.323 1.00 28.37 ? 314 GLY B N 1 ATOM 7943 C CA . GLY B 1 294 ? -1.544 9.723 36.185 1.00 28.33 ? 314 GLY B CA 1 ATOM 7944 C C . GLY B 1 294 ? -2.376 8.455 36.241 1.00 28.31 ? 314 GLY B C 1 ATOM 7945 O O . GLY B 1 294 ? -3.609 8.515 36.217 1.00 28.24 ? 314 GLY B O 1 ATOM 7946 N N . ASN B 1 295 ? -1.696 7.315 36.357 1.00 27.96 ? 315 ASN B N 1 ATOM 7947 C CA . ASN B 1 295 ? -2.359 6.030 36.511 1.00 27.72 ? 315 ASN B CA 1 ATOM 7948 C C . ASN B 1 295 ? -2.253 5.489 37.939 1.00 27.36 ? 315 ASN B C 1 ATOM 7949 O O . ASN B 1 295 ? -2.437 4.294 38.149 1.00 27.42 ? 315 ASN B O 1 ATOM 7950 C CB . ASN B 1 295 ? -1.789 5.021 35.498 1.00 27.93 ? 315 ASN B CB 1 ATOM 7951 C CG . ASN B 1 295 ? -0.403 4.497 35.890 1.00 27.82 ? 315 ASN B CG 1 ATOM 7952 O OD1 . ASN B 1 295 ? 0.431 5.244 36.391 1.00 31.29 ? 315 ASN B OD1 1 ATOM 7953 N ND2 . ASN B 1 295 ? -0.166 3.215 35.665 1.00 24.76 ? 315 ASN B ND2 1 ATOM 7954 N N . ALA B 1 296 ? -1.964 6.369 38.909 1.00 26.87 ? 316 ALA B N 1 ATOM 7955 C CA . ALA B 1 296 ? -1.808 5.987 40.323 1.00 26.40 ? 316 ALA B CA 1 ATOM 7956 C C . ALA B 1 296 ? -2.989 6.483 41.147 1.00 25.72 ? 316 ALA B C 1 ATOM 7957 O O . ALA B 1 296 ? -3.344 7.653 41.073 1.00 25.43 ? 316 ALA B O 1 ATOM 7958 C CB . ALA B 1 296 ? -0.508 6.561 40.903 1.00 26.45 ? 316 ALA B CB 1 ATOM 7959 N N . VAL B 1 297 ? -3.579 5.597 41.949 1.00 25.31 ? 317 VAL B N 1 ATOM 7960 C CA . VAL B 1 297 ? -4.744 5.957 42.765 1.00 24.62 ? 317 VAL B CA 1 ATOM 7961 C C . VAL B 1 297 ? -4.472 5.763 44.254 1.00 24.26 ? 317 VAL B C 1 ATOM 7962 O O . VAL B 1 297 ? -3.921 4.749 44.664 1.00 24.08 ? 317 VAL B O 1 ATOM 7963 C CB . VAL B 1 297 ? -5.984 5.140 42.361 1.00 24.89 ? 317 VAL B CB 1 ATOM 7964 C CG1 . VAL B 1 297 ? -7.213 5.558 43.209 1.00 24.20 ? 317 VAL B CG1 1 ATOM 7965 C CG2 . VAL B 1 297 ? -6.273 5.315 40.866 1.00 23.80 ? 317 VAL B CG2 1 ATOM 7966 N N . LEU B 1 298 ? -4.844 6.761 45.050 1.00 24.27 ? 318 LEU B N 1 ATOM 7967 C CA . LEU B 1 298 ? -4.838 6.657 46.511 1.00 24.27 ? 318 LEU B CA 1 ATOM 7968 C C . LEU B 1 298 ? -6.269 6.838 47.005 1.00 23.50 ? 318 LEU B C 1 ATOM 7969 O O . LEU B 1 298 ? -6.985 7.703 46.502 1.00 23.88 ? 318 LEU B O 1 ATOM 7970 C CB . LEU B 1 298 ? -3.951 7.737 47.135 1.00 24.51 ? 318 LEU B CB 1 ATOM 7971 C CG . LEU B 1 298 ? -2.501 7.818 46.656 1.00 26.48 ? 318 LEU B CG 1 ATOM 7972 C CD1 . LEU B 1 298 ? -1.892 9.155 47.097 1.00 27.83 ? 318 LEU B CD1 1 ATOM 7973 C CD2 . LEU B 1 298 ? -1.682 6.651 47.178 1.00 26.40 ? 318 LEU B CD2 1 ATOM 7974 N N . TYR B 1 299 ? -6.690 6.027 47.971 1.00 22.76 ? 319 TYR B N 1 ATOM 7975 C CA . TYR B 1 299 ? -8.047 6.136 48.542 1.00 22.32 ? 319 TYR B CA 1 ATOM 7976 C C . TYR B 1 299 ? -8.131 5.470 49.912 1.00 22.17 ? 319 TYR B C 1 ATOM 7977 O O . TYR B 1 299 ? -8.115 4.243 50.021 1.00 21.51 ? 319 TYR B O 1 ATOM 7978 C CB . TYR B 1 299 ? -9.065 5.514 47.592 1.00 22.19 ? 319 TYR B CB 1 ATOM 7979 C CG . TYR B 1 299 ? -10.470 5.355 48.136 1.00 21.54 ? 319 TYR B CG 1 ATOM 7980 C CD1 . TYR B 1 299 ? -11.271 6.456 48.390 1.00 21.81 ? 319 TYR B CD1 1 ATOM 7981 C CD2 . TYR B 1 299 ? -11.011 4.097 48.353 1.00 21.95 ? 319 TYR B CD2 1 ATOM 7982 C CE1 . TYR B 1 299 ? -12.576 6.307 48.871 1.00 21.64 ? 319 TYR B CE1 1 ATOM 7983 C CE2 . TYR B 1 299 ? -12.317 3.941 48.827 1.00 21.77 ? 319 TYR B CE2 1 ATOM 7984 C CZ . TYR B 1 299 ? -13.091 5.043 49.085 1.00 21.38 ? 319 TYR B CZ 1 ATOM 7985 O OH . TYR B 1 299 ? -14.391 4.876 49.553 1.00 22.57 ? 319 TYR B OH 1 ATOM 7986 N N . GLY B 1 300 ? -8.231 6.289 50.956 1.00 22.66 ? 320 GLY B N 1 ATOM 7987 C CA . GLY B 1 300 ? -8.146 5.799 52.327 1.00 22.72 ? 320 GLY B CA 1 ATOM 7988 C C . GLY B 1 300 ? -6.880 4.986 52.491 1.00 22.99 ? 320 GLY B C 1 ATOM 7989 O O . GLY B 1 300 ? -5.780 5.505 52.318 1.00 23.42 ? 320 GLY B O 1 ATOM 7990 N N . GLY B 1 301 ? -7.033 3.703 52.803 1.00 23.13 ? 321 GLY B N 1 ATOM 7991 C CA . GLY B 1 301 ? -5.885 2.823 52.972 1.00 23.05 ? 321 GLY B CA 1 ATOM 7992 C C . GLY B 1 301 ? -5.279 2.337 51.671 1.00 23.24 ? 321 GLY B C 1 ATOM 7993 O O . GLY B 1 301 ? -4.178 1.773 51.678 1.00 22.95 ? 321 GLY B O 1 ATOM 7994 N N . TRP B 1 302 ? -5.994 2.540 50.558 1.00 23.22 ? 322 TRP B N 1 ATOM 7995 C CA . TRP B 1 302 ? -5.638 1.908 49.287 1.00 23.19 ? 322 TRP B CA 1 ATOM 7996 C C . TRP B 1 302 ? -4.598 2.691 48.503 1.00 23.23 ? 322 TRP B C 1 ATOM 7997 O O . TRP B 1 302 ? -4.661 3.910 48.411 1.00 22.55 ? 322 TRP B O 1 ATOM 7998 C CB . TRP B 1 302 ? -6.858 1.741 48.379 1.00 22.90 ? 322 TRP B CB 1 ATOM 7999 C CG . TRP B 1 302 ? -7.868 0.772 48.863 1.00 22.56 ? 322 TRP B CG 1 ATOM 8000 C CD1 . TRP B 1 302 ? -9.046 1.064 49.479 1.00 20.79 ? 322 TRP B CD1 1 ATOM 8001 C CD2 . TRP B 1 302 ? -7.817 -0.651 48.750 1.00 22.13 ? 322 TRP B CD2 1 ATOM 8002 N NE1 . TRP B 1 302 ? -9.727 -0.084 49.766 1.00 21.40 ? 322 TRP B NE1 1 ATOM 8003 C CE2 . TRP B 1 302 ? -8.999 -1.156 49.331 1.00 21.85 ? 322 TRP B CE2 1 ATOM 8004 C CE3 . TRP B 1 302 ? -6.891 -1.549 48.223 1.00 21.86 ? 322 TRP B CE3 1 ATOM 8005 C CZ2 . TRP B 1 302 ? -9.279 -2.513 49.392 1.00 21.51 ? 322 TRP B CZ2 1 ATOM 8006 C CZ3 . TRP B 1 302 ? -7.168 -2.902 48.291 1.00 21.61 ? 322 TRP B CZ3 1 ATOM 8007 C CH2 . TRP B 1 302 ? -8.345 -3.370 48.877 1.00 21.85 ? 322 TRP B CH2 1 ATOM 8008 N N . SER B 1 303 ? -3.669 1.955 47.912 1.00 23.30 ? 323 SER B N 1 ATOM 8009 C CA . SER B 1 303 ? -2.797 2.487 46.880 1.00 23.86 ? 323 SER B CA 1 ATOM 8010 C C . SER B 1 303 ? -2.720 1.465 45.748 1.00 23.57 ? 323 SER B C 1 ATOM 8011 O O . SER B 1 303 ? -2.510 0.285 45.999 1.00 23.71 ? 323 SER B O 1 ATOM 8012 C CB . SER B 1 303 ? -1.398 2.747 47.449 1.00 23.91 ? 323 SER B CB 1 ATOM 8013 O OG . SER B 1 303 ? -0.549 3.226 46.425 1.00 26.19 ? 323 SER B OG 1 ATOM 8014 N N . PHE B 1 304 ? -2.914 1.909 44.509 1.00 23.74 ? 324 PHE B N 1 ATOM 8015 C CA . PHE B 1 304 ? -2.733 1.030 43.360 1.00 23.47 ? 324 PHE B CA 1 ATOM 8016 C C . PHE B 1 304 ? -2.505 1.799 42.058 1.00 23.38 ? 324 PHE B C 1 ATOM 8017 O O . PHE B 1 304 ? -2.783 3.004 41.962 1.00 23.11 ? 324 PHE B O 1 ATOM 8018 C CB . PHE B 1 304 ? -3.928 0.072 43.214 1.00 23.58 ? 324 PHE B CB 1 ATOM 8019 C CG . PHE B 1 304 ? -5.234 0.758 42.909 1.00 23.42 ? 324 PHE B CG 1 ATOM 8020 C CD1 . PHE B 1 304 ? -5.633 0.971 41.589 1.00 23.21 ? 324 PHE B CD1 1 ATOM 8021 C CD2 . PHE B 1 304 ? -6.072 1.167 43.937 1.00 22.98 ? 324 PHE B CD2 1 ATOM 8022 C CE1 . PHE B 1 304 ? -6.857 1.588 41.289 1.00 22.88 ? 324 PHE B CE1 1 ATOM 8023 C CE2 . PHE B 1 304 ? -7.292 1.782 43.661 1.00 22.45 ? 324 PHE B CE2 1 ATOM 8024 C CZ . PHE B 1 304 ? -7.687 1.999 42.329 1.00 23.24 ? 324 PHE B CZ 1 ATOM 8025 N N . ALA B 1 305 ? -1.984 1.072 41.070 1.00 23.15 ? 325 ALA B N 1 ATOM 8026 C CA . ALA B 1 305 ? -1.828 1.557 39.711 1.00 23.40 ? 325 ALA B CA 1 ATOM 8027 C C . ALA B 1 305 ? -2.796 0.795 38.826 1.00 23.56 ? 325 ALA B C 1 ATOM 8028 O O . ALA B 1 305 ? -3.296 -0.265 39.210 1.00 23.82 ? 325 ALA B O 1 ATOM 8029 C CB . ALA B 1 305 ? -0.407 1.337 39.222 1.00 23.15 ? 325 ALA B CB 1 ATOM 8030 N N . PHE B 1 306 ? -3.060 1.327 37.640 1.00 23.78 ? 326 PHE B N 1 ATOM 8031 C CA . PHE B 1 306 ? -3.930 0.635 36.687 1.00 24.39 ? 326 PHE B CA 1 ATOM 8032 C C . PHE B 1 306 ? -3.485 0.848 35.256 1.00 25.02 ? 326 PHE B C 1 ATOM 8033 O O . PHE B 1 306 ? -2.812 1.831 34.935 1.00 24.69 ? 326 PHE B O 1 ATOM 8034 C CB . PHE B 1 306 ? -5.397 1.080 36.847 1.00 24.28 ? 326 PHE B CB 1 ATOM 8035 C CG . PHE B 1 306 ? -5.630 2.522 36.539 1.00 24.16 ? 326 PHE B CG 1 ATOM 8036 C CD1 . PHE B 1 306 ? -5.907 2.929 35.245 1.00 23.45 ? 326 PHE B CD1 1 ATOM 8037 C CD2 . PHE B 1 306 ? -5.578 3.477 37.546 1.00 24.81 ? 326 PHE B CD2 1 ATOM 8038 C CE1 . PHE B 1 306 ? -6.118 4.270 34.950 1.00 24.33 ? 326 PHE B CE1 1 ATOM 8039 C CE2 . PHE B 1 306 ? -5.788 4.817 37.264 1.00 24.78 ? 326 PHE B CE2 1 ATOM 8040 C CZ . PHE B 1 306 ? -6.064 5.215 35.959 1.00 24.42 ? 326 PHE B CZ 1 ATOM 8041 N N . ARG B 1 307 ? -3.871 -0.086 34.398 1.00 26.08 ? 327 ARG B N 1 ATOM 8042 C CA . ARG B 1 307 ? -3.679 0.080 32.973 1.00 26.92 ? 327 ARG B CA 1 ATOM 8043 C C . ARG B 1 307 ? -4.830 -0.546 32.200 1.00 26.95 ? 327 ARG B C 1 ATOM 8044 O O . ARG B 1 307 ? -5.566 -1.391 32.723 1.00 26.97 ? 327 ARG B O 1 ATOM 8045 C CB . ARG B 1 307 ? -2.345 -0.523 32.537 1.00 27.33 ? 327 ARG B CB 1 ATOM 8046 C CG . ARG B 1 307 ? -2.311 -2.024 32.543 1.00 29.14 ? 327 ARG B CG 1 ATOM 8047 C CD . ARG B 1 307 ? -1.081 -2.555 31.835 1.00 31.77 ? 327 ARG B CD 1 ATOM 8048 N NE . ARG B 1 307 ? -1.065 -2.239 30.399 1.00 34.14 ? 327 ARG B NE 1 ATOM 8049 C CZ . ARG B 1 307 ? -0.239 -2.803 29.518 1.00 33.63 ? 327 ARG B CZ 1 ATOM 8050 N NH1 . ARG B 1 307 ? -0.288 -2.449 28.232 1.00 34.41 ? 327 ARG B NH1 1 ATOM 8051 N NH2 . ARG B 1 307 ? 0.628 -3.730 29.912 1.00 33.27 ? 327 ARG B NH2 1 ATOM 8052 N N . LEU B 1 308 ? -4.985 -0.092 30.965 1.00 26.83 ? 328 LEU B N 1 ATOM 8053 C CA . LEU B 1 308 ? -5.987 -0.605 30.067 1.00 26.93 ? 328 LEU B CA 1 ATOM 8054 C C . LEU B 1 308 ? -5.247 -1.197 28.873 1.00 26.97 ? 328 LEU B C 1 ATOM 8055 O O . LEU B 1 308 ? -4.854 -0.487 27.954 1.00 26.91 ? 328 LEU B O 1 ATOM 8056 C CB . LEU B 1 308 ? -6.939 0.507 29.640 1.00 26.67 ? 328 LEU B CB 1 ATOM 8057 C CG . LEU B 1 308 ? -8.115 0.068 28.761 1.00 27.17 ? 328 LEU B CG 1 ATOM 8058 C CD1 . LEU B 1 308 ? -8.822 -1.158 29.330 1.00 27.07 ? 328 LEU B CD1 1 ATOM 8059 C CD2 . LEU B 1 308 ? -9.092 1.216 28.611 1.00 27.09 ? 328 LEU B CD2 1 ATOM 8060 N N . ARG B 1 309 ? -5.049 -2.505 28.925 1.00 27.06 ? 329 ARG B N 1 ATOM 8061 C CA . ARG B 1 309 ? -4.316 -3.242 27.913 1.00 27.55 ? 329 ARG B CA 1 ATOM 8062 C C . ARG B 1 309 ? -5.220 -3.424 26.704 1.00 26.81 ? 329 ARG B C 1 ATOM 8063 O O . ARG B 1 309 ? -6.298 -4.015 26.821 1.00 26.67 ? 329 ARG B O 1 ATOM 8064 C CB . ARG B 1 309 ? -3.899 -4.594 28.495 1.00 28.18 ? 329 ARG B CB 1 ATOM 8065 C CG . ARG B 1 309 ? -2.811 -5.329 27.739 1.00 30.36 ? 329 ARG B CG 1 ATOM 8066 C CD . ARG B 1 309 ? -2.267 -6.481 28.567 1.00 33.04 ? 329 ARG B CD 1 ATOM 8067 N NE . ARG B 1 309 ? -1.189 -7.179 27.867 1.00 37.13 ? 329 ARG B NE 1 ATOM 8068 C CZ . ARG B 1 309 ? -1.263 -8.396 27.314 1.00 40.04 ? 329 ARG B CZ 1 ATOM 8069 N NH1 . ARG B 1 309 ? -2.382 -9.128 27.365 1.00 41.36 ? 329 ARG B NH1 1 ATOM 8070 N NH2 . ARG B 1 309 ? -0.189 -8.901 26.707 1.00 40.34 ? 329 ARG B NH2 1 ATOM 8071 N N . SER B 1 310 ? -4.803 -2.880 25.561 1.00 26.18 ? 330 SER B N 1 ATOM 8072 C CA . SER B 1 310 ? -5.630 -2.875 24.340 1.00 25.67 ? 330 SER B CA 1 ATOM 8073 C C . SER B 1 310 ? -6.091 -4.273 23.944 1.00 25.57 ? 330 SER B C 1 ATOM 8074 O O . SER B 1 310 ? -7.217 -4.444 23.472 1.00 25.48 ? 330 SER B O 1 ATOM 8075 C CB . SER B 1 310 ? -4.865 -2.241 23.168 1.00 25.63 ? 330 SER B CB 1 ATOM 8076 O OG . SER B 1 310 ? -4.502 -0.899 23.455 1.00 23.79 ? 330 SER B OG 1 ATOM 8077 N N . SER B 1 311 ? -5.218 -5.264 24.139 1.00 25.62 ? 331 SER B N 1 ATOM 8078 C CA . SER B 1 311 ? -5.517 -6.652 23.779 1.00 25.93 ? 331 SER B CA 1 ATOM 8079 C C . SER B 1 311 ? -6.520 -7.302 24.738 1.00 26.17 ? 331 SER B C 1 ATOM 8080 O O . SER B 1 311 ? -7.578 -7.773 24.294 1.00 27.83 ? 331 SER B O 1 ATOM 8081 C CB . SER B 1 311 ? -4.229 -7.491 23.684 1.00 25.60 ? 331 SER B CB 1 ATOM 8082 O OG . SER B 1 311 ? -3.417 -7.328 24.831 1.00 25.54 ? 331 SER B OG 1 ATOM 8083 N N . SER B 1 312 ? -6.230 -7.270 26.036 1.00 25.88 ? 332 SER B N 1 ATOM 8084 C CA . SER B 1 312 ? -6.943 -8.107 27.023 1.00 25.54 ? 332 SER B CA 1 ATOM 8085 C C . SER B 1 312 ? -7.837 -7.369 28.022 1.00 25.66 ? 332 SER B C 1 ATOM 8086 O O . SER B 1 312 ? -8.653 -8.002 28.680 1.00 25.79 ? 332 SER B O 1 ATOM 8087 C CB . SER B 1 312 ? -5.936 -8.931 27.817 1.00 25.43 ? 332 SER B CB 1 ATOM 8088 O OG . SER B 1 312 ? -5.085 -8.074 28.538 1.00 24.19 ? 332 SER B OG 1 ATOM 8089 N N . GLY B 1 313 ? -7.660 -6.056 28.163 1.00 25.49 ? 333 GLY B N 1 ATOM 8090 C CA . GLY B 1 313 ? -8.531 -5.245 29.004 1.00 25.12 ? 333 GLY B CA 1 ATOM 8091 C C . GLY B 1 313 ? -7.927 -4.768 30.313 1.00 25.18 ? 333 GLY B C 1 ATOM 8092 O O . GLY B 1 313 ? -6.698 -4.682 30.469 1.00 24.78 ? 333 GLY B O 1 ATOM 8093 N N . LEU B 1 314 ? -8.814 -4.474 31.261 1.00 24.75 ? 334 LEU B N 1 ATOM 8094 C CA . LEU B 1 314 ? -8.465 -3.747 32.474 1.00 24.80 ? 334 LEU B CA 1 ATOM 8095 C C . LEU B 1 314 ? -7.541 -4.519 33.423 1.00 24.83 ? 334 LEU B C 1 ATOM 8096 O O . LEU B 1 314 ? -7.675 -5.729 33.614 1.00 24.68 ? 334 LEU B O 1 ATOM 8097 C CB . LEU B 1 314 ? -9.745 -3.343 33.216 1.00 24.88 ? 334 LEU B CB 1 ATOM 8098 C CG . LEU B 1 314 ? -9.668 -2.228 34.268 1.00 25.08 ? 334 LEU B CG 1 ATOM 8099 C CD1 . LEU B 1 314 ? -9.048 -0.958 33.720 1.00 23.31 ? 334 LEU B CD1 1 ATOM 8100 C CD2 . LEU B 1 314 ? -11.079 -1.952 34.803 1.00 24.37 ? 334 LEU B CD2 1 ATOM 8101 N N . GLN B 1 315 ? -6.591 -3.800 34.010 1.00 24.72 ? 335 GLN B N 1 ATOM 8102 C CA . GLN B 1 315 ? -5.755 -4.361 35.071 1.00 24.64 ? 335 GLN B CA 1 ATOM 8103 C C . GLN B 1 315 ? -5.570 -3.371 36.197 1.00 24.02 ? 335 GLN B C 1 ATOM 8104 O O . GLN B 1 315 ? -5.505 -2.162 35.966 1.00 23.55 ? 335 GLN B O 1 ATOM 8105 C CB . GLN B 1 315 ? -4.378 -4.730 34.533 1.00 24.75 ? 335 GLN B CB 1 ATOM 8106 C CG . GLN B 1 315 ? -4.429 -5.500 33.249 1.00 25.87 ? 335 GLN B CG 1 ATOM 8107 C CD . GLN B 1 315 ? -3.079 -6.035 32.866 1.00 27.36 ? 335 GLN B CD 1 ATOM 8108 O OE1 . GLN B 1 315 ? -2.067 -5.632 33.425 1.00 28.35 ? 335 GLN B OE1 1 ATOM 8109 N NE2 . GLN B 1 315 ? -3.054 -6.944 31.902 1.00 27.88 ? 335 GLN B NE2 1 ATOM 8110 N N . VAL B 1 316 ? -5.497 -3.895 37.416 1.00 23.85 ? 336 VAL B N 1 ATOM 8111 C CA . VAL B 1 316 ? -5.010 -3.129 38.549 1.00 23.65 ? 336 VAL B CA 1 ATOM 8112 C C . VAL B 1 316 ? -3.726 -3.815 39.026 1.00 23.33 ? 336 VAL B C 1 ATOM 8113 O O . VAL B 1 316 ? -3.634 -5.046 39.030 1.00 22.64 ? 336 VAL B O 1 ATOM 8114 C CB . VAL B 1 316 ? -6.071 -2.991 39.662 1.00 23.78 ? 336 VAL B CB 1 ATOM 8115 C CG1 . VAL B 1 316 ? -7.357 -2.406 39.080 1.00 24.48 ? 336 VAL B CG1 1 ATOM 8116 C CG2 . VAL B 1 316 ? -6.351 -4.321 40.319 1.00 24.03 ? 336 VAL B CG2 1 ATOM 8117 N N . LEU B 1 317 ? -2.732 -3.015 39.399 1.00 23.20 ? 337 LEU B N 1 ATOM 8118 C CA . LEU B 1 317 ? -1.402 -3.538 39.729 1.00 23.23 ? 337 LEU B CA 1 ATOM 8119 C C . LEU B 1 317 ? -0.836 -2.902 40.990 1.00 23.14 ? 337 LEU B C 1 ATOM 8120 O O . LEU B 1 317 ? -1.183 -1.778 41.334 1.00 22.94 ? 337 LEU B O 1 ATOM 8121 C CB . LEU B 1 317 ? -0.436 -3.284 38.571 1.00 23.16 ? 337 LEU B CB 1 ATOM 8122 C CG . LEU B 1 317 ? -0.809 -4.003 37.267 1.00 23.26 ? 337 LEU B CG 1 ATOM 8123 C CD1 . LEU B 1 317 ? -0.801 -3.010 36.127 1.00 24.23 ? 337 LEU B CD1 1 ATOM 8124 C CD2 . LEU B 1 317 ? 0.093 -5.201 36.998 1.00 22.12 ? 337 LEU B CD2 1 ATOM 8125 N N . ASN B 1 318 ? 0.039 -3.645 41.662 1.00 23.10 ? 338 ASN B N 1 ATOM 8126 C CA . ASN B 1 318 ? 0.754 -3.168 42.839 1.00 23.14 ? 338 ASN B CA 1 ATOM 8127 C C . ASN B 1 318 ? -0.200 -2.682 43.918 1.00 22.76 ? 338 ASN B C 1 ATOM 8128 O O . ASN B 1 318 ? 0.026 -1.641 44.545 1.00 22.32 ? 338 ASN B O 1 ATOM 8129 C CB . ASN B 1 318 ? 1.741 -2.058 42.450 1.00 23.21 ? 338 ASN B CB 1 ATOM 8130 C CG . ASN B 1 318 ? 2.790 -1.833 43.507 1.00 23.48 ? 338 ASN B CG 1 ATOM 8131 O OD1 . ASN B 1 318 ? 3.196 -2.772 44.186 1.00 24.03 ? 338 ASN B OD1 1 ATOM 8132 N ND2 . ASN B 1 318 ? 3.234 -0.589 43.656 1.00 23.60 ? 338 ASN B ND2 1 ATOM 8133 N N . VAL B 1 319 ? -1.266 -3.456 44.128 1.00 22.74 ? 339 VAL B N 1 ATOM 8134 C CA . VAL B 1 319 ? -2.343 -3.056 45.013 1.00 22.78 ? 339 VAL B CA 1 ATOM 8135 C C . VAL B 1 319 ? -1.853 -3.175 46.447 1.00 23.04 ? 339 VAL B C 1 ATOM 8136 O O . VAL B 1 319 ? -1.400 -4.232 46.851 1.00 22.85 ? 339 VAL B O 1 ATOM 8137 C CB . VAL B 1 319 ? -3.633 -3.918 44.823 1.00 22.88 ? 339 VAL B CB 1 ATOM 8138 C CG1 . VAL B 1 319 ? -4.739 -3.402 45.725 1.00 22.54 ? 339 VAL B CG1 1 ATOM 8139 C CG2 . VAL B 1 319 ? -4.092 -3.920 43.366 1.00 22.25 ? 339 VAL B CG2 1 ATOM 8140 N N . HIS B 1 320 ? -1.942 -2.070 47.185 1.00 23.97 ? 340 HIS B N 1 ATOM 8141 C CA . HIS B 1 320 ? -1.531 -1.974 48.582 1.00 24.65 ? 340 HIS B CA 1 ATOM 8142 C C . HIS B 1 320 ? -2.718 -1.553 49.445 1.00 25.46 ? 340 HIS B C 1 ATOM 8143 O O . HIS B 1 320 ? -3.549 -0.760 49.008 1.00 25.59 ? 340 HIS B O 1 ATOM 8144 C CB . HIS B 1 320 ? -0.458 -0.890 48.739 1.00 24.79 ? 340 HIS B CB 1 ATOM 8145 C CG . HIS B 1 320 ? 0.929 -1.331 48.395 1.00 24.51 ? 340 HIS B CG 1 ATOM 8146 N ND1 . HIS B 1 320 ? 1.325 -1.611 47.109 1.00 25.90 ? 340 HIS B ND1 1 ATOM 8147 C CD2 . HIS B 1 320 ? 2.024 -1.502 49.172 1.00 25.13 ? 340 HIS B CD2 1 ATOM 8148 C CE1 . HIS B 1 320 ? 2.602 -1.959 47.111 1.00 26.24 ? 340 HIS B CE1 1 ATOM 8149 N NE2 . HIS B 1 320 ? 3.050 -1.897 48.350 1.00 24.91 ? 340 HIS B NE2 1 ATOM 8150 N N . PHE B 1 321 ? -2.783 -2.063 50.673 1.00 26.36 ? 341 PHE B N 1 ATOM 8151 C CA . PHE B 1 321 ? -3.626 -1.460 51.705 1.00 27.41 ? 341 PHE B CA 1 ATOM 8152 C C . PHE B 1 321 ? -2.804 -1.269 52.976 1.00 28.18 ? 341 PHE B C 1 ATOM 8153 O O . PHE B 1 321 ? -2.170 -2.208 53.439 1.00 28.58 ? 341 PHE B O 1 ATOM 8154 C CB . PHE B 1 321 ? -4.862 -2.309 52.002 1.00 27.29 ? 341 PHE B CB 1 ATOM 8155 C CG . PHE B 1 321 ? -5.915 -1.586 52.799 1.00 27.81 ? 341 PHE B CG 1 ATOM 8156 C CD1 . PHE B 1 321 ? -7.060 -1.116 52.186 1.00 28.07 ? 341 PHE B CD1 1 ATOM 8157 C CD2 . PHE B 1 321 ? -5.756 -1.365 54.156 1.00 29.36 ? 341 PHE B CD2 1 ATOM 8158 C CE1 . PHE B 1 321 ? -8.040 -0.450 52.911 1.00 29.27 ? 341 PHE B CE1 1 ATOM 8159 C CE2 . PHE B 1 321 ? -6.734 -0.704 54.892 1.00 29.60 ? 341 PHE B CE2 1 ATOM 8160 C CZ . PHE B 1 321 ? -7.880 -0.243 54.264 1.00 29.06 ? 341 PHE B CZ 1 ATOM 8161 N N . GLY B 1 322 ? -2.821 -0.058 53.529 1.00 28.96 ? 342 GLY B N 1 ATOM 8162 C CA . GLY B 1 322 ? -2.083 0.246 54.754 1.00 29.32 ? 342 GLY B CA 1 ATOM 8163 C C . GLY B 1 322 ? -0.581 0.193 54.550 1.00 29.81 ? 342 GLY B C 1 ATOM 8164 O O . GLY B 1 322 ? 0.164 -0.172 55.458 1.00 30.62 ? 342 GLY B O 1 ATOM 8165 N N . GLY B 1 323 ? -0.136 0.552 53.351 1.00 30.00 ? 343 GLY B N 1 ATOM 8166 C CA . GLY B 1 323 ? 1.281 0.512 53.004 1.00 29.82 ? 343 GLY B CA 1 ATOM 8167 C C . GLY B 1 323 ? 1.830 -0.883 52.778 1.00 29.96 ? 343 GLY B C 1 ATOM 8168 O O . GLY B 1 323 ? 3.042 -1.044 52.592 1.00 30.63 ? 343 GLY B O 1 ATOM 8169 N N . GLU B 1 324 ? 0.962 -1.896 52.778 1.00 29.28 ? 344 GLU B N 1 ATOM 8170 C CA . GLU B 1 324 ? 1.405 -3.268 52.547 1.00 28.81 ? 344 GLU B CA 1 ATOM 8171 C C . GLU B 1 324 ? 0.794 -3.880 51.286 1.00 27.77 ? 344 GLU B C 1 ATOM 8172 O O . GLU B 1 324 ? -0.393 -3.691 51.008 1.00 27.01 ? 344 GLU B O 1 ATOM 8173 C CB . GLU B 1 324 ? 1.087 -4.119 53.756 1.00 29.15 ? 344 GLU B CB 1 ATOM 8174 C CG . GLU B 1 324 ? 1.933 -3.733 54.956 1.00 30.65 ? 344 GLU B CG 1 ATOM 8175 C CD . GLU B 1 324 ? 1.722 -4.662 56.094 1.00 31.02 ? 344 GLU B CD 1 ATOM 8176 O OE1 . GLU B 1 324 ? 0.647 -4.586 56.719 1.00 33.23 ? 344 GLU B OE1 1 ATOM 8177 O OE2 . GLU B 1 324 ? 2.615 -5.487 56.354 1.00 31.46 ? 344 GLU B OE2 1 ATOM 8178 N N . ARG B 1 325 ? 1.620 -4.606 50.531 1.00 26.71 ? 345 ARG B N 1 ATOM 8179 C CA . ARG B 1 325 ? 1.184 -5.180 49.267 1.00 26.00 ? 345 ARG B CA 1 ATOM 8180 C C . ARG B 1 325 ? 0.205 -6.318 49.493 1.00 25.44 ? 345 ARG B C 1 ATOM 8181 O O . ARG B 1 325 ? 0.390 -7.149 50.392 1.00 24.92 ? 345 ARG B O 1 ATOM 8182 C CB . ARG B 1 325 ? 2.354 -5.677 48.412 1.00 25.99 ? 345 ARG B CB 1 ATOM 8183 C CG . ARG B 1 325 ? 1.898 -6.104 47.002 1.00 25.82 ? 345 ARG B CG 1 ATOM 8184 C CD . ARG B 1 325 ? 3.055 -6.381 46.061 1.00 25.99 ? 345 ARG B CD 1 ATOM 8185 N NE . ARG B 1 325 ? 3.715 -5.135 45.672 1.00 26.93 ? 345 ARG B NE 1 ATOM 8186 C CZ . ARG B 1 325 ? 4.966 -4.792 45.982 1.00 27.06 ? 345 ARG B CZ 1 ATOM 8187 N NH1 . ARG B 1 325 ? 5.747 -5.613 46.677 1.00 26.89 ? 345 ARG B NH1 1 ATOM 8188 N NH2 . ARG B 1 325 ? 5.441 -3.617 45.576 1.00 26.09 ? 345 ARG B NH2 1 ATOM 8189 N N . ILE B 1 326 ? -0.838 -6.327 48.666 1.00 24.52 ? 346 ILE B N 1 ATOM 8190 C CA . ILE B 1 326 ? -1.850 -7.376 48.668 1.00 24.51 ? 346 ILE B CA 1 ATOM 8191 C C . ILE B 1 326 ? -1.822 -8.197 47.364 1.00 23.69 ? 346 ILE B C 1 ATOM 8192 O O . ILE B 1 326 ? -1.851 -9.424 47.393 1.00 23.14 ? 346 ILE B O 1 ATOM 8193 C CB . ILE B 1 326 ? -3.233 -6.741 48.857 1.00 24.88 ? 346 ILE B CB 1 ATOM 8194 C CG1 . ILE B 1 326 ? -3.317 -6.138 50.263 1.00 25.90 ? 346 ILE B CG1 1 ATOM 8195 C CG2 . ILE B 1 326 ? -4.330 -7.760 48.637 1.00 25.17 ? 346 ILE B CG2 1 ATOM 8196 C CD1 . ILE B 1 326 ? -4.513 -5.222 50.451 1.00 28.23 ? 346 ILE B CD1 1 ATOM 8197 N N . ALA B 1 327 ? -1.769 -7.507 46.228 1.00 23.12 ? 347 ALA B N 1 ATOM 8198 C CA . ALA B 1 327 ? -1.726 -8.155 44.919 1.00 22.74 ? 347 ALA B CA 1 ATOM 8199 C C . ALA B 1 327 ? -0.844 -7.359 43.961 1.00 22.50 ? 347 ALA B C 1 ATOM 8200 O O . ALA B 1 327 ? -0.988 -6.137 43.852 1.00 22.40 ? 347 ALA B O 1 ATOM 8201 C CB . ALA B 1 327 ? -3.138 -8.288 44.343 1.00 22.63 ? 347 ALA B CB 1 ATOM 8202 N N . TYR B 1 328 ? 0.059 -8.049 43.262 1.00 22.29 ? 348 TYR B N 1 ATOM 8203 C CA . TYR B 1 328 ? 0.883 -7.401 42.232 1.00 22.07 ? 348 TYR B CA 1 ATOM 8204 C C . TYR B 1 328 ? 0.066 -7.129 40.970 1.00 21.95 ? 348 TYR B C 1 ATOM 8205 O O . TYR B 1 328 ? 0.269 -6.101 40.306 1.00 22.05 ? 348 TYR B O 1 ATOM 8206 C CB . TYR B 1 328 ? 2.109 -8.261 41.880 1.00 22.04 ? 348 TYR B CB 1 ATOM 8207 C CG . TYR B 1 328 ? 3.015 -7.648 40.826 1.00 22.12 ? 348 TYR B CG 1 ATOM 8208 C CD1 . TYR B 1 328 ? 3.921 -6.643 41.162 1.00 22.98 ? 348 TYR B CD1 1 ATOM 8209 C CD2 . TYR B 1 328 ? 2.974 -8.076 39.503 1.00 23.20 ? 348 TYR B CD2 1 ATOM 8210 C CE1 . TYR B 1 328 ? 4.759 -6.087 40.228 1.00 23.00 ? 348 TYR B CE1 1 ATOM 8211 C CE2 . TYR B 1 328 ? 3.812 -7.515 38.543 1.00 23.56 ? 348 TYR B CE2 1 ATOM 8212 C CZ . TYR B 1 328 ? 4.704 -6.518 38.921 1.00 24.08 ? 348 TYR B CZ 1 ATOM 8213 O OH . TYR B 1 328 ? 5.535 -5.951 38.003 1.00 24.24 ? 348 TYR B OH 1 ATOM 8214 N N . GLU B 1 329 ? -0.851 -8.043 40.648 1.00 21.74 ? 349 GLU B N 1 ATOM 8215 C CA . GLU B 1 329 ? -1.677 -7.938 39.440 1.00 21.58 ? 349 GLU B CA 1 ATOM 8216 C C . GLU B 1 329 ? -3.043 -8.591 39.608 1.00 21.26 ? 349 GLU B C 1 ATOM 8217 O O . GLU B 1 329 ? -3.133 -9.724 40.074 1.00 20.52 ? 349 GLU B O 1 ATOM 8218 C CB . GLU B 1 329 ? -0.983 -8.612 38.254 1.00 21.55 ? 349 GLU B CB 1 ATOM 8219 C CG . GLU B 1 329 ? -1.822 -8.627 36.991 1.00 22.66 ? 349 GLU B CG 1 ATOM 8220 C CD . GLU B 1 329 ? -1.183 -9.383 35.840 1.00 24.71 ? 349 GLU B CD 1 ATOM 8221 O OE1 . GLU B 1 329 ? -0.069 -9.931 36.021 1.00 25.46 ? 349 GLU B OE1 1 ATOM 8222 O OE2 . GLU B 1 329 ? -1.820 -9.441 34.761 1.00 23.46 ? 349 GLU B OE2 1 ATOM 8223 N N . VAL B 1 330 ? -4.092 -7.858 39.224 1.00 21.18 ? 350 VAL B N 1 ATOM 8224 C CA . VAL B 1 330 ? -5.422 -8.428 39.025 1.00 21.07 ? 350 VAL B CA 1 ATOM 8225 C C . VAL B 1 330 ? -5.896 -7.990 37.647 1.00 20.78 ? 350 VAL B C 1 ATOM 8226 O O . VAL B 1 330 ? -6.036 -6.794 37.382 1.00 20.50 ? 350 VAL B O 1 ATOM 8227 C CB . VAL B 1 330 ? -6.428 -8.000 40.114 1.00 21.36 ? 350 VAL B CB 1 ATOM 8228 C CG1 . VAL B 1 330 ? -7.696 -8.854 40.030 1.00 20.30 ? 350 VAL B CG1 1 ATOM 8229 C CG2 . VAL B 1 330 ? -5.808 -8.133 41.497 1.00 21.31 ? 350 VAL B CG2 1 ATOM 8230 N N . SER B 1 331 ? -6.123 -8.961 36.762 1.00 20.80 ? 351 SER B N 1 ATOM 8231 C CA . SER B 1 331 ? -6.396 -8.668 35.354 1.00 20.56 ? 351 SER B CA 1 ATOM 8232 C C . SER B 1 331 ? -7.388 -9.612 34.688 1.00 20.19 ? 351 SER B C 1 ATOM 8233 O O . SER B 1 331 ? -7.373 -10.824 34.925 1.00 19.89 ? 351 SER B O 1 ATOM 8234 C CB . SER B 1 331 ? -5.091 -8.712 34.553 1.00 20.99 ? 351 SER B CB 1 ATOM 8235 O OG . SER B 1 331 ? -4.404 -9.931 34.748 1.00 20.92 ? 351 SER B OG 1 ATOM 8236 N N . VAL B 1 332 ? -8.215 -9.036 33.819 1.00 19.92 ? 352 VAL B N 1 ATOM 8237 C CA . VAL B 1 332 ? -9.025 -9.801 32.889 1.00 19.97 ? 352 VAL B CA 1 ATOM 8238 C C . VAL B 1 332 ? -8.109 -10.464 31.874 1.00 19.91 ? 352 VAL B C 1 ATOM 8239 O O . VAL B 1 332 ? -7.260 -9.801 31.282 1.00 19.99 ? 352 VAL B O 1 ATOM 8240 C CB . VAL B 1 332 ? -10.023 -8.897 32.128 1.00 20.33 ? 352 VAL B CB 1 ATOM 8241 C CG1 . VAL B 1 332 ? -10.884 -9.744 31.184 1.00 19.91 ? 352 VAL B CG1 1 ATOM 8242 C CG2 . VAL B 1 332 ? -10.901 -8.085 33.116 1.00 20.16 ? 352 VAL B CG2 1 ATOM 8243 N N . GLN B 1 333 ? -8.293 -11.763 31.665 1.00 20.11 ? 353 GLN B N 1 ATOM 8244 C CA . GLN B 1 333 ? -7.465 -12.541 30.736 1.00 20.32 ? 353 GLN B CA 1 ATOM 8245 C C . GLN B 1 333 ? -8.180 -12.971 29.459 1.00 20.41 ? 353 GLN B C 1 ATOM 8246 O O . GLN B 1 333 ? -7.551 -13.075 28.408 1.00 19.84 ? 353 GLN B O 1 ATOM 8247 C CB . GLN B 1 333 ? -6.948 -13.788 31.441 1.00 20.43 ? 353 GLN B CB 1 ATOM 8248 C CG . GLN B 1 333 ? -6.002 -13.479 32.591 1.00 21.87 ? 353 GLN B CG 1 ATOM 8249 C CD . GLN B 1 333 ? -4.670 -12.936 32.109 1.00 22.20 ? 353 GLN B CD 1 ATOM 8250 O OE1 . GLN B 1 333 ? -4.050 -13.513 31.223 1.00 23.62 ? 353 GLN B OE1 1 ATOM 8251 N NE2 . GLN B 1 333 ? -4.222 -11.835 32.696 1.00 22.88 ? 353 GLN B NE2 1 ATOM 8252 N N . GLU B 1 334 ? -9.475 -13.269 29.561 1.00 20.34 ? 354 GLU B N 1 ATOM 8253 C CA . GLU B 1 334 ? -10.266 -13.699 28.407 1.00 20.53 ? 354 GLU B CA 1 ATOM 8254 C C . GLU B 1 334 ? -11.737 -13.729 28.818 1.00 20.48 ? 354 GLU B C 1 ATOM 8255 O O . GLU B 1 334 ? -12.060 -13.860 30.003 1.00 20.22 ? 354 GLU B O 1 ATOM 8256 C CB . GLU B 1 334 ? -9.798 -15.081 27.924 1.00 20.95 ? 354 GLU B CB 1 ATOM 8257 C CG . GLU B 1 334 ? -10.493 -15.680 26.686 1.00 21.52 ? 354 GLU B CG 1 ATOM 8258 C CD . GLU B 1 334 ? -10.345 -14.845 25.417 1.00 22.51 ? 354 GLU B CD 1 ATOM 8259 O OE1 . GLU B 1 334 ? -9.466 -15.160 24.574 1.00 22.15 ? 354 GLU B OE1 1 ATOM 8260 O OE2 . GLU B 1 334 ? -11.112 -13.874 25.266 1.00 22.00 ? 354 GLU B OE2 1 ATOM 8261 N N . ALA B 1 335 ? -12.611 -13.586 27.831 1.00 20.22 ? 355 ALA B N 1 ATOM 8262 C CA . ALA B 1 335 ? -14.052 -13.584 28.043 1.00 20.25 ? 355 ALA B CA 1 ATOM 8263 C C . ALA B 1 335 ? -14.652 -14.262 26.834 1.00 20.19 ? 355 ALA B C 1 ATOM 8264 O O . ALA B 1 335 ? -14.382 -13.854 25.701 1.00 19.80 ? 355 ALA B O 1 ATOM 8265 C CB . ALA B 1 335 ? -14.577 -12.166 28.169 1.00 20.14 ? 355 ALA B CB 1 ATOM 8266 N N . VAL B 1 336 ? -15.447 -15.303 27.074 1.00 19.76 ? 356 VAL B N 1 ATOM 8267 C CA . VAL B 1 336 ? -15.940 -16.144 26.005 1.00 19.30 ? 356 VAL B CA 1 ATOM 8268 C C . VAL B 1 336 ? -17.448 -16.309 26.102 1.00 18.98 ? 356 VAL B C 1 ATOM 8269 O O . VAL B 1 336 ? -18.032 -16.161 27.178 1.00 18.62 ? 356 VAL B O 1 ATOM 8270 C CB . VAL B 1 336 ? -15.225 -17.535 25.979 1.00 19.60 ? 356 VAL B CB 1 ATOM 8271 C CG1 . VAL B 1 336 ? -13.672 -17.366 26.003 1.00 19.24 ? 356 VAL B CG1 1 ATOM 8272 C CG2 . VAL B 1 336 ? -15.680 -18.417 27.142 1.00 19.82 ? 356 VAL B CG2 1 ATOM 8273 N N . ALA B 1 337 ? -18.061 -16.569 24.950 1.00 18.46 ? 357 ALA B N 1 ATOM 8274 C CA . ALA B 1 337 ? -19.470 -16.915 24.851 1.00 18.57 ? 357 ALA B CA 1 ATOM 8275 C C . ALA B 1 337 ? -19.570 -18.127 23.921 1.00 18.73 ? 357 ALA B C 1 ATOM 8276 O O . ALA B 1 337 ? -19.237 -18.053 22.730 1.00 18.79 ? 357 ALA B O 1 ATOM 8277 C CB . ALA B 1 337 ? -20.289 -15.736 24.335 1.00 18.64 ? 357 ALA B CB 1 ATOM 8278 N N . LEU B 1 338 ? -19.975 -19.252 24.501 1.00 18.76 ? 358 LEU B N 1 ATOM 8279 C CA . LEU B 1 338 ? -19.960 -20.542 23.847 1.00 18.85 ? 358 LEU B CA 1 ATOM 8280 C C . LEU B 1 338 ? -21.399 -20.958 23.532 1.00 19.12 ? 358 LEU B C 1 ATOM 8281 O O . LEU B 1 338 ? -22.194 -21.225 24.444 1.00 18.83 ? 358 LEU B O 1 ATOM 8282 C CB . LEU B 1 338 ? -19.303 -21.566 24.770 1.00 19.02 ? 358 LEU B CB 1 ATOM 8283 C CG . LEU B 1 338 ? -17.924 -21.159 25.311 1.00 20.06 ? 358 LEU B CG 1 ATOM 8284 C CD1 . LEU B 1 338 ? -17.386 -22.195 26.293 1.00 19.48 ? 358 LEU B CD1 1 ATOM 8285 C CD2 . LEU B 1 338 ? -16.938 -20.930 24.156 1.00 19.30 ? 358 LEU B CD2 1 ATOM 8286 N N . TYR B 1 339 ? -21.714 -21.024 22.240 1.00 18.97 ? 359 TYR B N 1 ATOM 8287 C CA . TYR B 1 339 ? -23.087 -21.210 21.779 1.00 18.96 ? 359 TYR B CA 1 ATOM 8288 C C . TYR B 1 339 ? -23.416 -22.613 21.306 1.00 19.00 ? 359 TYR B C 1 ATOM 8289 O O . TYR B 1 339 ? -22.532 -23.389 20.950 1.00 19.09 ? 359 TYR B O 1 ATOM 8290 C CB . TYR B 1 339 ? -23.387 -20.228 20.644 1.00 18.84 ? 359 TYR B CB 1 ATOM 8291 C CG . TYR B 1 339 ? -23.415 -18.809 21.138 1.00 18.46 ? 359 TYR B CG 1 ATOM 8292 C CD1 . TYR B 1 339 ? -24.618 -18.192 21.449 1.00 18.00 ? 359 TYR B CD1 1 ATOM 8293 C CD2 . TYR B 1 339 ? -22.236 -18.100 21.336 1.00 16.85 ? 359 TYR B CD2 1 ATOM 8294 C CE1 . TYR B 1 339 ? -24.651 -16.900 21.926 1.00 18.13 ? 359 TYR B CE1 1 ATOM 8295 C CE2 . TYR B 1 339 ? -22.256 -16.815 21.806 1.00 17.44 ? 359 TYR B CE2 1 ATOM 8296 C CZ . TYR B 1 339 ? -23.468 -16.210 22.110 1.00 18.55 ? 359 TYR B CZ 1 ATOM 8297 O OH . TYR B 1 339 ? -23.513 -14.914 22.600 1.00 18.57 ? 359 TYR B OH 1 ATOM 8298 N N . GLY B 1 340 ? -24.710 -22.919 21.345 1.00 18.67 ? 360 GLY B N 1 ATOM 8299 C CA . GLY B 1 340 ? -25.291 -24.024 20.602 1.00 19.07 ? 360 GLY B CA 1 ATOM 8300 C C . GLY B 1 340 ? -26.296 -23.441 19.619 1.00 19.37 ? 360 GLY B C 1 ATOM 8301 O O . GLY B 1 340 ? -26.742 -22.296 19.781 1.00 19.59 ? 360 GLY B O 1 ATOM 8302 N N . GLY B 1 341 ? -26.649 -24.207 18.595 1.00 19.73 ? 361 GLY B N 1 ATOM 8303 C CA . GLY B 1 341 ? -27.612 -23.729 17.611 1.00 20.05 ? 361 GLY B CA 1 ATOM 8304 C C . GLY B 1 341 ? -28.125 -24.758 16.630 1.00 20.27 ? 361 GLY B C 1 ATOM 8305 O O . GLY B 1 341 ? -27.512 -25.797 16.417 1.00 20.04 ? 361 GLY B O 1 ATOM 8306 N N . HIS B 1 342 ? -29.268 -24.430 16.032 1.00 20.69 ? 362 HIS B N 1 ATOM 8307 C CA . HIS B 1 342 ? -29.862 -25.189 14.943 1.00 21.27 ? 362 HIS B CA 1 ATOM 8308 C C . HIS B 1 342 ? -29.310 -24.769 13.584 1.00 21.27 ? 362 HIS B C 1 ATOM 8309 O O . HIS B 1 342 ? -29.286 -25.578 12.656 1.00 21.87 ? 362 HIS B O 1 ATOM 8310 C CB . HIS B 1 342 ? -31.395 -25.028 14.934 1.00 21.52 ? 362 HIS B CB 1 ATOM 8311 C CG . HIS B 1 342 ? -31.872 -23.614 14.765 1.00 23.34 ? 362 HIS B CG 1 ATOM 8312 N ND1 . HIS B 1 342 ? -31.503 -22.588 15.614 1.00 26.31 ? 362 HIS B ND1 1 ATOM 8313 C CD2 . HIS B 1 342 ? -32.731 -23.067 13.871 1.00 26.08 ? 362 HIS B CD2 1 ATOM 8314 C CE1 . HIS B 1 342 ? -32.092 -21.467 15.231 1.00 26.69 ? 362 HIS B CE1 1 ATOM 8315 N NE2 . HIS B 1 342 ? -32.859 -21.735 14.187 1.00 25.86 ? 362 HIS B NE2 1 ATOM 8316 N N . THR B 1 343 ? -28.904 -23.510 13.446 1.00 20.96 ? 363 THR B N 1 ATOM 8317 C CA . THR B 1 343 ? -28.330 -23.031 12.187 1.00 20.92 ? 363 THR B CA 1 ATOM 8318 C C . THR B 1 343 ? -26.814 -23.238 12.226 1.00 20.68 ? 363 THR B C 1 ATOM 8319 O O . THR B 1 343 ? -26.224 -23.297 13.300 1.00 21.08 ? 363 THR B O 1 ATOM 8320 C CB . THR B 1 343 ? -28.656 -21.527 11.915 1.00 20.99 ? 363 THR B CB 1 ATOM 8321 O OG1 . THR B 1 343 ? -27.745 -20.693 12.639 1.00 21.00 ? 363 THR B OG1 1 ATOM 8322 C CG2 . THR B 1 343 ? -30.110 -21.173 12.310 1.00 21.52 ? 363 THR B CG2 1 ATOM 8323 N N . PRO B 1 344 ? -26.175 -23.370 11.059 1.00 20.61 ? 364 PRO B N 1 ATOM 8324 C CA . PRO B 1 344 ? -24.722 -23.588 11.075 1.00 20.67 ? 364 PRO B CA 1 ATOM 8325 C C . PRO B 1 344 ? -23.905 -22.468 11.746 1.00 20.43 ? 364 PRO B C 1 ATOM 8326 O O . PRO B 1 344 ? -22.915 -22.758 12.405 1.00 20.40 ? 364 PRO B O 1 ATOM 8327 C CB . PRO B 1 344 ? -24.354 -23.745 9.600 1.00 20.65 ? 364 PRO B CB 1 ATOM 8328 C CG . PRO B 1 344 ? -25.568 -23.316 8.820 1.00 21.70 ? 364 PRO B CG 1 ATOM 8329 C CD . PRO B 1 344 ? -26.753 -23.485 9.709 1.00 20.68 ? 364 PRO B CD 1 ATOM 8330 N N . ALA B 1 345 ? -24.315 -21.213 11.597 1.00 20.33 ? 365 ALA B N 1 ATOM 8331 C CA . ALA B 1 345 ? -23.652 -20.106 12.294 1.00 20.15 ? 365 ALA B CA 1 ATOM 8332 C C . ALA B 1 345 ? -23.748 -20.301 13.802 1.00 20.40 ? 365 ALA B C 1 ATOM 8333 O O . ALA B 1 345 ? -22.764 -20.162 14.510 1.00 20.25 ? 365 ALA B O 1 ATOM 8334 C CB . ALA B 1 345 ? -24.255 -18.787 11.895 1.00 19.86 ? 365 ALA B CB 1 ATOM 8335 N N . GLY B 1 346 ? -24.946 -20.638 14.273 1.00 20.86 ? 366 GLY B N 1 ATOM 8336 C CA . GLY B 1 346 ? -25.202 -20.866 15.686 1.00 20.96 ? 366 GLY B CA 1 ATOM 8337 C C . GLY B 1 346 ? -24.366 -21.971 16.289 1.00 20.98 ? 366 GLY B C 1 ATOM 8338 O O . GLY B 1 346 ? -23.735 -21.783 17.331 1.00 21.21 ? 366 GLY B O 1 ATOM 8339 N N . MET B 1 347 ? -24.344 -23.128 15.640 1.00 20.81 ? 367 MET B N 1 ATOM 8340 C CA . MET B 1 347 ? -23.555 -24.238 16.162 1.00 20.96 ? 367 MET B CA 1 ATOM 8341 C C . MET B 1 347 ? -22.035 -24.018 15.996 1.00 20.54 ? 367 MET B C 1 ATOM 8342 O O . MET B 1 347 ? -21.246 -24.670 16.675 1.00 19.36 ? 367 MET B O 1 ATOM 8343 C CB . MET B 1 347 ? -24.018 -25.590 15.585 1.00 21.37 ? 367 MET B CB 1 ATOM 8344 C CG . MET B 1 347 ? -23.821 -25.773 14.103 1.00 22.51 ? 367 MET B CG 1 ATOM 8345 S SD . MET B 1 347 ? -24.441 -27.370 13.541 1.00 23.70 ? 367 MET B SD 1 ATOM 8346 C CE . MET B 1 347 ? -26.222 -27.155 13.567 1.00 20.49 ? 367 MET B CE 1 ATOM 8347 N N . GLN B 1 348 ? -21.642 -23.058 15.155 1.00 20.45 ? 368 GLN B N 1 ATOM 8348 C CA . GLN B 1 348 ? -20.229 -22.718 14.966 1.00 20.46 ? 368 GLN B CA 1 ATOM 8349 C C . GLN B 1 348 ? -19.657 -21.795 16.050 1.00 20.80 ? 368 GLN B C 1 ATOM 8350 O O . GLN B 1 348 ? -18.450 -21.829 16.317 1.00 21.64 ? 368 GLN B O 1 ATOM 8351 C CB . GLN B 1 348 ? -20.035 -22.067 13.600 1.00 20.17 ? 368 GLN B CB 1 ATOM 8352 C CG . GLN B 1 348 ? -18.579 -21.859 13.182 1.00 20.24 ? 368 GLN B CG 1 ATOM 8353 C CD . GLN B 1 348 ? -17.828 -23.156 12.973 1.00 19.31 ? 368 GLN B CD 1 ATOM 8354 O OE1 . GLN B 1 348 ? -18.421 -24.197 12.713 1.00 20.08 ? 368 GLN B OE1 1 ATOM 8355 N NE2 . GLN B 1 348 ? -16.517 -23.096 13.087 1.00 20.55 ? 368 GLN B NE2 1 ATOM 8356 N N . THR B 1 349 ? -20.513 -20.992 16.681 1.00 20.80 ? 369 THR B N 1 ATOM 8357 C CA . THR B 1 349 ? -20.058 -19.830 17.450 1.00 20.38 ? 369 THR B CA 1 ATOM 8358 C C . THR B 1 349 ? -19.453 -20.154 18.811 1.00 20.56 ? 369 THR B C 1 ATOM 8359 O O . THR B 1 349 ? -20.140 -20.603 19.745 1.00 19.94 ? 369 THR B O 1 ATOM 8360 C CB . THR B 1 349 ? -21.189 -18.801 17.669 1.00 20.49 ? 369 THR B CB 1 ATOM 8361 O OG1 . THR B 1 349 ? -21.846 -18.516 16.428 1.00 20.19 ? 369 THR B OG1 1 ATOM 8362 C CG2 . THR B 1 349 ? -20.631 -17.518 18.246 1.00 18.98 ? 369 THR B CG2 1 ATOM 8363 N N . LYS B 1 350 ? -18.151 -19.913 18.911 1.00 20.83 ? 370 LYS B N 1 ATOM 8364 C CA . LYS B 1 350 ? -17.466 -19.859 20.187 1.00 21.19 ? 370 LYS B CA 1 ATOM 8365 C C . LYS B 1 350 ? -16.638 -18.582 20.154 1.00 21.55 ? 370 LYS B C 1 ATOM 8366 O O . LYS B 1 350 ? -15.521 -18.569 19.614 1.00 21.73 ? 370 LYS B O 1 ATOM 8367 C CB . LYS B 1 350 ? -16.573 -21.078 20.386 1.00 21.33 ? 370 LYS B CB 1 ATOM 8368 C CG . LYS B 1 350 ? -17.326 -22.375 20.455 1.00 22.26 ? 370 LYS B CG 1 ATOM 8369 C CD . LYS B 1 350 ? -16.402 -23.544 20.698 1.00 23.71 ? 370 LYS B CD 1 ATOM 8370 C CE . LYS B 1 350 ? -17.161 -24.862 20.627 1.00 24.21 ? 370 LYS B CE 1 ATOM 8371 N NZ . LYS B 1 350 ? -17.630 -25.142 19.235 1.00 25.22 ? 370 LYS B NZ 1 ATOM 8372 N N . TYR B 1 351 ? -17.202 -17.502 20.686 1.00 21.14 ? 371 TYR B N 1 ATOM 8373 C CA . TYR B 1 351 ? -16.536 -16.217 20.629 1.00 21.44 ? 371 TYR B CA 1 ATOM 8374 C C . TYR B 1 351 ? -15.536 -16.136 21.774 1.00 21.65 ? 371 TYR B C 1 ATOM 8375 O O . TYR B 1 351 ? -15.862 -16.465 22.917 1.00 21.65 ? 371 TYR B O 1 ATOM 8376 C CB . TYR B 1 351 ? -17.521 -15.048 20.750 1.00 21.53 ? 371 TYR B CB 1 ATOM 8377 C CG . TYR B 1 351 ? -18.286 -14.674 19.497 1.00 21.62 ? 371 TYR B CG 1 ATOM 8378 C CD1 . TYR B 1 351 ? -17.630 -14.401 18.290 1.00 21.86 ? 371 TYR B CD1 1 ATOM 8379 C CD2 . TYR B 1 351 ? -19.672 -14.534 19.530 1.00 19.72 ? 371 TYR B CD2 1 ATOM 8380 C CE1 . TYR B 1 351 ? -18.355 -14.025 17.152 1.00 20.10 ? 371 TYR B CE1 1 ATOM 8381 C CE2 . TYR B 1 351 ? -20.390 -14.166 18.409 1.00 19.80 ? 371 TYR B CE2 1 ATOM 8382 C CZ . TYR B 1 351 ? -19.736 -13.917 17.221 1.00 20.18 ? 371 TYR B CZ 1 ATOM 8383 O OH . TYR B 1 351 ? -20.478 -13.541 16.103 1.00 20.88 ? 371 TYR B OH 1 ATOM 8384 N N . LEU B 1 352 ? -14.327 -15.701 21.448 1.00 21.71 ? 372 LEU B N 1 ATOM 8385 C CA . LEU B 1 352 ? -13.265 -15.463 22.419 1.00 22.14 ? 372 LEU B CA 1 ATOM 8386 C C . LEU B 1 352 ? -12.837 -14.016 22.182 1.00 22.30 ? 372 LEU B C 1 ATOM 8387 O O . LEU B 1 352 ? -12.180 -13.709 21.187 1.00 21.56 ? 372 LEU B O 1 ATOM 8388 C CB . LEU B 1 352 ? -12.087 -16.418 22.192 1.00 22.40 ? 372 LEU B CB 1 ATOM 8389 C CG . LEU B 1 352 ? -12.206 -17.846 22.728 1.00 22.80 ? 372 LEU B CG 1 ATOM 8390 C CD1 . LEU B 1 352 ? -13.472 -18.539 22.242 1.00 24.14 ? 372 LEU B CD1 1 ATOM 8391 C CD2 . LEU B 1 352 ? -10.986 -18.663 22.342 1.00 24.04 ? 372 LEU B CD2 1 ATOM 8392 N N . ASP B 1 353 ? -13.223 -13.134 23.096 1.00 22.79 ? 373 ASP B N 1 ATOM 8393 C CA . ASP B 1 353 ? -13.203 -11.703 22.829 1.00 23.42 ? 373 ASP B CA 1 ATOM 8394 C C . ASP B 1 353 ? -11.833 -11.048 22.884 1.00 23.07 ? 373 ASP B C 1 ATOM 8395 O O . ASP B 1 353 ? -11.673 -9.942 22.381 1.00 23.03 ? 373 ASP B O 1 ATOM 8396 C CB . ASP B 1 353 ? -14.186 -10.988 23.760 1.00 23.98 ? 373 ASP B CB 1 ATOM 8397 C CG . ASP B 1 353 ? -15.621 -11.390 23.489 1.00 25.99 ? 373 ASP B CG 1 ATOM 8398 O OD1 . ASP B 1 353 ? -15.961 -11.738 22.326 1.00 29.47 ? 373 ASP B OD1 1 ATOM 8399 O OD2 . ASP B 1 353 ? -16.416 -11.378 24.439 1.00 30.50 ? 373 ASP B OD2 1 ATOM 8400 N N . VAL B 1 354 ? -10.838 -11.703 23.476 1.00 22.79 ? 374 VAL B N 1 ATOM 8401 C CA . VAL B 1 354 ? -9.482 -11.175 23.379 1.00 22.50 ? 374 VAL B CA 1 ATOM 8402 C C . VAL B 1 354 ? -9.047 -11.233 21.910 1.00 22.68 ? 374 VAL B C 1 ATOM 8403 O O . VAL B 1 354 ? -8.306 -10.368 21.451 1.00 23.04 ? 374 VAL B O 1 ATOM 8404 C CB . VAL B 1 354 ? -8.491 -11.900 24.306 1.00 22.56 ? 374 VAL B CB 1 ATOM 8405 C CG1 . VAL B 1 354 ? -7.030 -11.519 23.973 1.00 22.04 ? 374 VAL B CG1 1 ATOM 8406 C CG2 . VAL B 1 354 ? -8.811 -11.565 25.754 1.00 21.89 ? 374 VAL B CG2 1 ATOM 8407 N N . GLY B 1 355 ? -9.566 -12.208 21.160 1.00 22.52 ? 375 GLY B N 1 ATOM 8408 C CA . GLY B 1 355 ? -9.357 -12.256 19.715 1.00 22.70 ? 375 GLY B CA 1 ATOM 8409 C C . GLY B 1 355 ? -9.945 -11.087 18.935 1.00 22.96 ? 375 GLY B C 1 ATOM 8410 O O . GLY B 1 355 ? -9.768 -11.017 17.723 1.00 22.91 ? 375 GLY B O 1 ATOM 8411 N N . TRP B 1 356 ? -10.635 -10.175 19.630 1.00 23.28 ? 376 TRP B N 1 ATOM 8412 C CA . TRP B 1 356 ? -11.261 -8.985 19.034 1.00 23.51 ? 376 TRP B CA 1 ATOM 8413 C C . TRP B 1 356 ? -10.790 -7.678 19.684 1.00 23.75 ? 376 TRP B C 1 ATOM 8414 O O . TRP B 1 356 ? -11.428 -6.645 19.518 1.00 24.60 ? 376 TRP B O 1 ATOM 8415 C CB . TRP B 1 356 ? -12.793 -9.085 19.173 1.00 23.39 ? 376 TRP B CB 1 ATOM 8416 C CG . TRP B 1 356 ? -13.349 -10.285 18.486 1.00 23.00 ? 376 TRP B CG 1 ATOM 8417 C CD1 . TRP B 1 356 ? -13.397 -11.545 18.965 1.00 21.71 ? 376 TRP B CD1 1 ATOM 8418 C CD2 . TRP B 1 356 ? -13.916 -10.329 17.170 1.00 22.67 ? 376 TRP B CD2 1 ATOM 8419 N NE1 . TRP B 1 356 ? -13.969 -12.389 18.037 1.00 23.22 ? 376 TRP B NE1 1 ATOM 8420 C CE2 . TRP B 1 356 ? -14.293 -11.663 16.923 1.00 22.06 ? 376 TRP B CE2 1 ATOM 8421 C CE3 . TRP B 1 356 ? -14.139 -9.367 16.179 1.00 22.45 ? 376 TRP B CE3 1 ATOM 8422 C CZ2 . TRP B 1 356 ? -14.879 -12.066 15.722 1.00 22.65 ? 376 TRP B CZ2 1 ATOM 8423 C CZ3 . TRP B 1 356 ? -14.713 -9.766 14.982 1.00 22.45 ? 376 TRP B CZ3 1 ATOM 8424 C CH2 . TRP B 1 356 ? -15.078 -11.106 14.763 1.00 22.09 ? 376 TRP B CH2 1 ATOM 8425 N N . GLY B 1 357 ? -9.684 -7.709 20.420 1.00 23.73 ? 377 GLY B N 1 ATOM 8426 C CA . GLY B 1 357 ? -9.224 -6.517 21.150 1.00 23.60 ? 377 GLY B CA 1 ATOM 8427 C C . GLY B 1 357 ? -10.198 -6.089 22.234 1.00 23.36 ? 377 GLY B C 1 ATOM 8428 O O . GLY B 1 357 ? -10.760 -5.007 22.184 1.00 23.72 ? 377 GLY B O 1 ATOM 8429 N N . LEU B 1 358 ? -10.401 -6.961 23.214 1.00 23.41 ? 378 LEU B N 1 ATOM 8430 C CA . LEU B 1 358 ? -11.330 -6.718 24.312 1.00 23.11 ? 378 LEU B CA 1 ATOM 8431 C C . LEU B 1 358 ? -11.046 -5.368 24.984 1.00 22.69 ? 378 LEU B C 1 ATOM 8432 O O . LEU B 1 358 ? -11.965 -4.614 25.314 1.00 22.20 ? 378 LEU B O 1 ATOM 8433 C CB . LEU B 1 358 ? -11.212 -7.867 25.323 1.00 23.45 ? 378 LEU B CB 1 ATOM 8434 C CG . LEU B 1 358 ? -12.231 -7.965 26.453 1.00 24.02 ? 378 LEU B CG 1 ATOM 8435 C CD1 . LEU B 1 358 ? -13.652 -7.990 25.901 1.00 25.92 ? 378 LEU B CD1 1 ATOM 8436 C CD2 . LEU B 1 358 ? -11.961 -9.220 27.254 1.00 23.89 ? 378 LEU B CD2 1 ATOM 8437 N N . GLY B 1 359 ? -9.763 -5.053 25.130 1.00 22.57 ? 379 GLY B N 1 ATOM 8438 C CA . GLY B 1 359 ? -9.326 -3.835 25.795 1.00 22.33 ? 379 GLY B CA 1 ATOM 8439 C C . GLY B 1 359 ? -9.309 -2.570 24.961 1.00 22.27 ? 379 GLY B C 1 ATOM 8440 O O . GLY B 1 359 ? -8.973 -1.514 25.481 1.00 22.10 ? 379 GLY B O 1 ATOM 8441 N N . SER B 1 360 ? -9.670 -2.645 23.679 1.00 22.21 ? 380 SER B N 1 ATOM 8442 C CA . SER B 1 360 ? -9.668 -1.443 22.841 1.00 22.16 ? 380 SER B CA 1 ATOM 8443 C C . SER B 1 360 ? -11.029 -1.109 22.218 1.00 22.16 ? 380 SER B C 1 ATOM 8444 O O . SER B 1 360 ? -11.113 -0.299 21.294 1.00 22.53 ? 380 SER B O 1 ATOM 8445 C CB . SER B 1 360 ? -8.575 -1.539 21.765 1.00 22.32 ? 380 SER B CB 1 ATOM 8446 O OG . SER B 1 360 ? -8.745 -2.662 20.935 1.00 22.59 ? 380 SER B OG 1 ATOM 8447 N N . VAL B 1 361 ? -12.087 -1.722 22.742 1.00 21.53 ? 381 VAL B N 1 ATOM 8448 C CA . VAL B 1 361 ? -13.447 -1.393 22.369 1.00 21.15 ? 381 VAL B CA 1 ATOM 8449 C C . VAL B 1 361 ? -14.103 -0.723 23.581 1.00 21.44 ? 381 VAL B C 1 ATOM 8450 O O . VAL B 1 361 ? -15.299 -0.896 23.869 1.00 21.48 ? 381 VAL B O 1 ATOM 8451 C CB . VAL B 1 361 ? -14.234 -2.628 21.870 1.00 21.49 ? 381 VAL B CB 1 ATOM 8452 C CG1 . VAL B 1 361 ? -13.885 -2.922 20.390 1.00 20.79 ? 381 VAL B CG1 1 ATOM 8453 C CG2 . VAL B 1 361 ? -14.000 -3.848 22.752 1.00 20.44 ? 381 VAL B CG2 1 ATOM 8454 N N . THR B 1 362 ? -13.282 0.079 24.256 1.00 21.24 ? 382 THR B N 1 ATOM 8455 C CA . THR B 1 362 ? -13.633 0.780 25.471 1.00 21.14 ? 382 THR B CA 1 ATOM 8456 C C . THR B 1 362 ? -14.274 2.103 25.076 1.00 21.23 ? 382 THR B C 1 ATOM 8457 O O . THR B 1 362 ? -13.657 3.161 25.184 1.00 21.29 ? 382 THR B O 1 ATOM 8458 C CB . THR B 1 362 ? -12.365 1.043 26.302 1.00 21.36 ? 382 THR B CB 1 ATOM 8459 O OG1 . THR B 1 362 ? -11.400 1.729 25.493 1.00 20.94 ? 382 THR B OG1 1 ATOM 8460 C CG2 . THR B 1 362 ? -11.756 -0.264 26.785 1.00 20.94 ? 382 THR B CG2 1 ATOM 8461 N N . HIS B 1 363 ? -15.511 2.034 24.590 1.00 21.10 ? 383 HIS B N 1 ATOM 8462 C CA . HIS B 1 363 ? -16.138 3.191 23.970 1.00 20.90 ? 383 HIS B CA 1 ATOM 8463 C C . HIS B 1 363 ? -16.754 4.118 25.009 1.00 20.74 ? 383 HIS B C 1 ATOM 8464 O O . HIS B 1 363 ? -16.858 3.771 26.194 1.00 20.68 ? 383 HIS B O 1 ATOM 8465 C CB . HIS B 1 363 ? -17.121 2.758 22.871 1.00 21.08 ? 383 HIS B CB 1 ATOM 8466 C CG . HIS B 1 363 ? -16.435 2.382 21.595 1.00 21.99 ? 383 HIS B CG 1 ATOM 8467 N ND1 . HIS B 1 363 ? -15.796 3.307 20.797 1.00 23.97 ? 383 HIS B ND1 1 ATOM 8468 C CD2 . HIS B 1 363 ? -16.243 1.181 21.004 1.00 23.88 ? 383 HIS B CD2 1 ATOM 8469 C CE1 . HIS B 1 363 ? -15.265 2.694 19.755 1.00 23.69 ? 383 HIS B CE1 1 ATOM 8470 N NE2 . HIS B 1 363 ? -15.515 1.401 19.861 1.00 24.00 ? 383 HIS B NE2 1 ATOM 8471 N N . GLU B 1 364 ? -17.159 5.298 24.557 1.00 20.48 ? 384 GLU B N 1 ATOM 8472 C CA . GLU B 1 364 ? -17.381 6.435 25.459 1.00 20.62 ? 384 GLU B CA 1 ATOM 8473 C C . GLU B 1 364 ? -18.422 6.206 26.549 1.00 20.21 ? 384 GLU B C 1 ATOM 8474 O O . GLU B 1 364 ? -19.562 5.883 26.270 1.00 20.34 ? 384 GLU B O 1 ATOM 8475 C CB . GLU B 1 364 ? -17.743 7.681 24.652 1.00 20.32 ? 384 GLU B CB 1 ATOM 8476 C CG . GLU B 1 364 ? -17.875 8.964 25.472 1.00 20.69 ? 384 GLU B CG 1 ATOM 8477 C CD . GLU B 1 364 ? -18.121 10.186 24.597 1.00 21.23 ? 384 GLU B CD 1 ATOM 8478 O OE1 . GLU B 1 364 ? -17.911 10.089 23.372 1.00 21.60 ? 384 GLU B OE1 1 ATOM 8479 O OE2 . GLU B 1 364 ? -18.514 11.244 25.128 1.00 21.55 ? 384 GLU B OE2 1 ATOM 8480 N N . LEU B 1 365 ? -18.011 6.413 27.793 1.00 20.21 ? 385 LEU B N 1 ATOM 8481 C CA . LEU B 1 365 ? -18.910 6.301 28.930 1.00 20.20 ? 385 LEU B CA 1 ATOM 8482 C C . LEU B 1 365 ? -19.798 7.536 29.021 1.00 20.40 ? 385 LEU B C 1 ATOM 8483 O O . LEU B 1 365 ? -19.307 8.662 28.985 1.00 20.33 ? 385 LEU B O 1 ATOM 8484 C CB . LEU B 1 365 ? -18.115 6.118 30.214 1.00 19.90 ? 385 LEU B CB 1 ATOM 8485 C CG . LEU B 1 365 ? -17.309 4.824 30.275 1.00 20.02 ? 385 LEU B CG 1 ATOM 8486 C CD1 . LEU B 1 365 ? -16.201 4.898 31.345 1.00 19.82 ? 385 LEU B CD1 1 ATOM 8487 C CD2 . LEU B 1 365 ? -18.235 3.622 30.504 1.00 18.80 ? 385 LEU B CD2 1 ATOM 8488 N N . ALA B 1 366 ? -21.109 7.313 29.117 1.00 20.72 ? 386 ALA B N 1 ATOM 8489 C CA . ALA B 1 366 ? -22.092 8.393 29.153 1.00 20.92 ? 386 ALA B CA 1 ATOM 8490 C C . ALA B 1 366 ? -22.278 8.844 30.597 1.00 21.26 ? 386 ALA B C 1 ATOM 8491 O O . ALA B 1 366 ? -22.758 8.065 31.427 1.00 21.36 ? 386 ALA B O 1 ATOM 8492 C CB . ALA B 1 366 ? -23.412 7.938 28.558 1.00 20.67 ? 386 ALA B CB 1 ATOM 8493 N N . PRO B 1 367 ? -21.897 10.098 30.908 1.00 21.60 ? 387 PRO B N 1 ATOM 8494 C CA . PRO B 1 367 ? -21.975 10.572 32.295 1.00 21.60 ? 387 PRO B CA 1 ATOM 8495 C C . PRO B 1 367 ? -23.400 10.592 32.839 1.00 21.83 ? 387 PRO B C 1 ATOM 8496 O O . PRO B 1 367 ? -24.299 11.093 32.180 1.00 21.51 ? 387 PRO B O 1 ATOM 8497 C CB . PRO B 1 367 ? -21.405 11.996 32.222 1.00 21.63 ? 387 PRO B CB 1 ATOM 8498 C CG . PRO B 1 367 ? -20.592 12.031 30.976 1.00 21.70 ? 387 PRO B CG 1 ATOM 8499 C CD . PRO B 1 367 ? -21.319 11.123 30.014 1.00 21.63 ? 387 PRO B CD 1 ATOM 8500 N N . GLY B 1 368 ? -23.592 10.024 34.025 1.00 22.14 ? 388 GLY B N 1 ATOM 8501 C CA . GLY B 1 368 ? -24.921 9.901 34.621 1.00 22.71 ? 388 GLY B CA 1 ATOM 8502 C C . GLY B 1 368 ? -25.556 8.540 34.423 1.00 23.01 ? 388 GLY B C 1 ATOM 8503 O O . GLY B 1 368 ? -26.380 8.126 35.240 1.00 24.25 ? 388 GLY B O 1 ATOM 8504 N N . ILE B 1 369 ? -25.157 7.838 33.360 1.00 22.91 ? 389 ILE B N 1 ATOM 8505 C CA . ILE B 1 369 ? -25.730 6.549 32.987 1.00 22.39 ? 389 ILE B CA 1 ATOM 8506 C C . ILE B 1 369 ? -24.691 5.437 33.225 1.00 22.38 ? 389 ILE B C 1 ATOM 8507 O O . ILE B 1 369 ? -24.868 4.591 34.106 1.00 21.93 ? 389 ILE B O 1 ATOM 8508 C CB . ILE B 1 369 ? -26.204 6.580 31.507 1.00 22.48 ? 389 ILE B CB 1 ATOM 8509 C CG1 . ILE B 1 369 ? -27.182 7.745 31.277 1.00 22.88 ? 389 ILE B CG1 1 ATOM 8510 C CG2 . ILE B 1 369 ? -26.845 5.256 31.095 1.00 22.29 ? 389 ILE B CG2 1 ATOM 8511 C CD1 . ILE B 1 369 ? -27.867 7.732 29.894 1.00 21.92 ? 389 ILE B CD1 1 ATOM 8512 N N . ASP B 1 370 ? -23.587 5.465 32.473 1.00 21.99 ? 390 ASP B N 1 ATOM 8513 C CA . ASP B 1 370 ? -22.542 4.449 32.614 1.00 21.54 ? 390 ASP B CA 1 ATOM 8514 C C . ASP B 1 370 ? -21.741 4.578 33.912 1.00 21.27 ? 390 ASP B C 1 ATOM 8515 O O . ASP B 1 370 ? -21.380 3.587 34.512 1.00 20.73 ? 390 ASP B O 1 ATOM 8516 C CB . ASP B 1 370 ? -21.611 4.484 31.410 1.00 22.02 ? 390 ASP B CB 1 ATOM 8517 C CG . ASP B 1 370 ? -22.307 4.058 30.132 1.00 22.21 ? 390 ASP B CG 1 ATOM 8518 O OD1 . ASP B 1 370 ? -23.182 3.157 30.187 1.00 24.57 ? 390 ASP B OD1 1 ATOM 8519 O OD2 . ASP B 1 370 ? -21.984 4.623 29.075 1.00 21.11 ? 390 ASP B OD2 1 ATOM 8520 N N . CYS B 1 371 ? -21.465 5.811 34.321 1.00 21.17 ? 391 CYS B N 1 ATOM 8521 C CA . CYS B 1 371 ? -20.919 6.116 35.631 1.00 21.26 ? 391 CYS B CA 1 ATOM 8522 C C . CYS B 1 371 ? -21.696 7.322 36.187 1.00 21.20 ? 391 CYS B C 1 ATOM 8523 O O . CYS B 1 371 ? -22.333 8.053 35.423 1.00 20.83 ? 391 CYS B O 1 ATOM 8524 C CB . CYS B 1 371 ? -19.432 6.455 35.520 1.00 21.52 ? 391 CYS B CB 1 ATOM 8525 S SG . CYS B 1 371 ? -18.489 5.357 34.420 1.00 21.96 ? 391 CYS B SG 1 ATOM 8526 N N . PRO B 1 372 ? -21.653 7.532 37.513 1.00 21.51 ? 392 PRO B N 1 ATOM 8527 C CA . PRO B 1 372 ? -22.366 8.692 38.063 1.00 21.74 ? 392 PRO B CA 1 ATOM 8528 C C . PRO B 1 372 ? -21.901 10.018 37.456 1.00 22.00 ? 392 PRO B C 1 ATOM 8529 O O . PRO B 1 372 ? -20.762 10.123 36.960 1.00 21.29 ? 392 PRO B O 1 ATOM 8530 C CB . PRO B 1 372 ? -22.046 8.639 39.566 1.00 21.55 ? 392 PRO B CB 1 ATOM 8531 C CG . PRO B 1 372 ? -21.681 7.217 39.838 1.00 22.48 ? 392 PRO B CG 1 ATOM 8532 C CD . PRO B 1 372 ? -21.050 6.694 38.568 1.00 21.59 ? 392 PRO B CD 1 ATOM 8533 N N . GLU B 1 373 ? -22.788 11.013 37.508 1.00 22.13 ? 393 GLU B N 1 ATOM 8534 C CA . GLU B 1 373 ? -22.531 12.332 36.943 1.00 22.83 ? 393 GLU B CA 1 ATOM 8535 C C . GLU B 1 373 ? -21.299 12.952 37.594 1.00 22.44 ? 393 GLU B C 1 ATOM 8536 O O . GLU B 1 373 ? -20.633 13.794 37.002 1.00 22.33 ? 393 GLU B O 1 ATOM 8537 C CB . GLU B 1 373 ? -23.731 13.261 37.164 1.00 23.51 ? 393 GLU B CB 1 ATOM 8538 C CG . GLU B 1 373 ? -25.055 12.812 36.509 1.00 26.08 ? 393 GLU B CG 1 ATOM 8539 C CD . GLU B 1 373 ? -25.932 11.904 37.385 1.00 28.47 ? 393 GLU B CD 1 ATOM 8540 O OE1 . GLU B 1 373 ? -25.415 11.104 38.206 1.00 27.88 ? 393 GLU B OE1 1 ATOM 8541 O OE2 . GLU B 1 373 ? -27.174 11.974 37.223 1.00 33.58 ? 393 GLU B OE2 1 ATOM 8542 N N . THR B 1 374 ? -21.036 12.519 38.826 1.00 22.11 ? 394 THR B N 1 ATOM 8543 C CA . THR B 1 374 ? -19.950 12.999 39.641 1.00 22.02 ? 394 THR B CA 1 ATOM 8544 C C . THR B 1 374 ? -18.615 12.285 39.385 1.00 22.32 ? 394 THR B C 1 ATOM 8545 O O . THR B 1 374 ? -17.607 12.604 40.033 1.00 22.50 ? 394 THR B O 1 ATOM 8546 C CB . THR B 1 374 ? -20.321 12.802 41.124 1.00 22.29 ? 394 THR B CB 1 ATOM 8547 O OG1 . THR B 1 374 ? -20.842 11.471 41.316 1.00 21.01 ? 394 THR B OG1 1 ATOM 8548 C CG2 . THR B 1 374 ? -21.372 13.826 41.558 1.00 21.93 ? 394 THR B CG2 1 ATOM 8549 N N . ALA B 1 375 ? -18.597 11.323 38.462 1.00 21.63 ? 395 ALA B N 1 ATOM 8550 C CA . ALA B 1 375 ? -17.414 10.486 38.271 1.00 21.52 ? 395 ALA B CA 1 ATOM 8551 C C . ALA B 1 375 ? -16.264 11.224 37.579 1.00 21.15 ? 395 ALA B C 1 ATOM 8552 O O . ALA B 1 375 ? -16.488 12.156 36.817 1.00 21.17 ? 395 ALA B O 1 ATOM 8553 C CB . ALA B 1 375 ? -17.777 9.216 37.486 1.00 20.99 ? 395 ALA B CB 1 ATOM 8554 N N . THR B 1 376 ? -15.034 10.795 37.849 1.00 20.87 ? 396 THR B N 1 ATOM 8555 C CA . THR B 1 376 ? -13.880 11.258 37.072 1.00 21.09 ? 396 THR B CA 1 ATOM 8556 C C . THR B 1 376 ? -13.762 10.378 35.823 1.00 21.44 ? 396 THR B C 1 ATOM 8557 O O . THR B 1 376 ? -13.575 9.167 35.933 1.00 20.87 ? 396 THR B O 1 ATOM 8558 C CB . THR B 1 376 ? -12.584 11.205 37.904 1.00 20.99 ? 396 THR B CB 1 ATOM 8559 O OG1 . THR B 1 376 ? -12.737 12.045 39.059 1.00 20.12 ? 396 THR B OG1 1 ATOM 8560 C CG2 . THR B 1 376 ? -11.368 11.667 37.080 1.00 20.87 ? 396 THR B CG2 1 ATOM 8561 N N . PHE B 1 377 ? -13.892 10.987 34.645 1.00 21.88 ? 397 PHE B N 1 ATOM 8562 C CA . PHE B 1 377 ? -13.820 10.247 33.385 1.00 22.74 ? 397 PHE B CA 1 ATOM 8563 C C . PHE B 1 377 ? -12.434 10.371 32.773 1.00 22.98 ? 397 PHE B C 1 ATOM 8564 O O . PHE B 1 377 ? -11.872 11.457 32.724 1.00 23.43 ? 397 PHE B O 1 ATOM 8565 C CB . PHE B 1 377 ? -14.889 10.755 32.415 1.00 22.92 ? 397 PHE B CB 1 ATOM 8566 C CG . PHE B 1 377 ? -16.282 10.588 32.932 1.00 23.74 ? 397 PHE B CG 1 ATOM 8567 C CD1 . PHE B 1 377 ? -16.862 11.566 33.731 1.00 23.17 ? 397 PHE B CD1 1 ATOM 8568 C CD2 . PHE B 1 377 ? -17.002 9.433 32.660 1.00 24.34 ? 397 PHE B CD2 1 ATOM 8569 C CE1 . PHE B 1 377 ? -18.150 11.397 34.238 1.00 23.20 ? 397 PHE B CE1 1 ATOM 8570 C CE2 . PHE B 1 377 ? -18.293 9.267 33.159 1.00 24.19 ? 397 PHE B CE2 1 ATOM 8571 C CZ . PHE B 1 377 ? -18.860 10.253 33.949 1.00 23.11 ? 397 PHE B CZ 1 ATOM 8572 N N . LEU B 1 378 ? -11.896 9.259 32.292 1.00 23.46 ? 398 LEU B N 1 ATOM 8573 C CA . LEU B 1 378 ? -10.515 9.210 31.809 1.00 23.82 ? 398 LEU B CA 1 ATOM 8574 C C . LEU B 1 378 ? -10.457 8.757 30.360 1.00 24.01 ? 398 LEU B C 1 ATOM 8575 O O . LEU B 1 378 ? -11.111 7.777 29.953 1.00 23.29 ? 398 LEU B O 1 ATOM 8576 C CB . LEU B 1 378 ? -9.679 8.256 32.659 1.00 24.10 ? 398 LEU B CB 1 ATOM 8577 C CG . LEU B 1 378 ? -9.621 8.545 34.154 1.00 25.05 ? 398 LEU B CG 1 ATOM 8578 C CD1 . LEU B 1 378 ? -8.753 7.517 34.833 1.00 24.17 ? 398 LEU B CD1 1 ATOM 8579 C CD2 . LEU B 1 378 ? -9.103 9.965 34.406 1.00 25.93 ? 398 LEU B CD2 1 ATOM 8580 N N . ASP B 1 379 ? -9.659 9.480 29.586 1.00 24.22 ? 399 ASP B N 1 ATOM 8581 C CA . ASP B 1 379 ? -9.439 9.152 28.191 1.00 24.29 ? 399 ASP B CA 1 ATOM 8582 C C . ASP B 1 379 ? -8.315 8.157 28.063 1.00 24.31 ? 399 ASP B C 1 ATOM 8583 O O . ASP B 1 379 ? -7.563 7.929 29.011 1.00 24.41 ? 399 ASP B O 1 ATOM 8584 C CB . ASP B 1 379 ? -9.094 10.408 27.404 1.00 24.43 ? 399 ASP B CB 1 ATOM 8585 C CG . ASP B 1 379 ? -10.230 11.417 27.385 1.00 25.25 ? 399 ASP B CG 1 ATOM 8586 O OD1 . ASP B 1 379 ? -11.284 11.185 28.031 1.00 25.55 ? 399 ASP B OD1 1 ATOM 8587 O OD2 . ASP B 1 379 ? -10.063 12.450 26.717 1.00 27.04 ? 399 ASP B OD2 1 ATOM 8588 N N . THR B 1 380 ? -8.213 7.549 26.885 1.00 23.96 ? 400 THR B N 1 ATOM 8589 C CA . THR B 1 380 ? -7.073 6.729 26.568 1.00 23.97 ? 400 THR B CA 1 ATOM 8590 C C . THR B 1 380 ? -6.820 6.708 25.068 1.00 24.00 ? 400 THR B C 1 ATOM 8591 O O . THR B 1 380 ? -7.637 7.184 24.274 1.00 23.57 ? 400 THR B O 1 ATOM 8592 C CB . THR B 1 380 ? -7.246 5.292 27.092 1.00 24.34 ? 400 THR B CB 1 ATOM 8593 O OG1 . THR B 1 380 ? -5.958 4.672 27.190 1.00 24.97 ? 400 THR B OG1 1 ATOM 8594 C CG2 . THR B 1 380 ? -8.169 4.459 26.177 1.00 22.97 ? 400 THR B CG2 1 ATOM 8595 N N . PHE B 1 381 ? -5.667 6.163 24.701 1.00 23.89 ? 401 PHE B N 1 ATOM 8596 C CA . PHE B 1 381 ? -5.290 6.002 23.302 1.00 23.94 ? 401 PHE B CA 1 ATOM 8597 C C . PHE B 1 381 ? -5.120 4.513 23.002 1.00 23.67 ? 401 PHE B C 1 ATOM 8598 O O . PHE B 1 381 ? -4.553 3.785 23.810 1.00 23.59 ? 401 PHE B O 1 ATOM 8599 C CB . PHE B 1 381 ? -3.988 6.772 23.013 1.00 24.14 ? 401 PHE B CB 1 ATOM 8600 C CG . PHE B 1 381 ? -4.194 8.239 22.735 1.00 24.41 ? 401 PHE B CG 1 ATOM 8601 C CD1 . PHE B 1 381 ? -4.161 9.168 23.765 1.00 24.72 ? 401 PHE B CD1 1 ATOM 8602 C CD2 . PHE B 1 381 ? -4.416 8.687 21.434 1.00 24.95 ? 401 PHE B CD2 1 ATOM 8603 C CE1 . PHE B 1 381 ? -4.357 10.521 23.510 1.00 24.90 ? 401 PHE B CE1 1 ATOM 8604 C CE2 . PHE B 1 381 ? -4.613 10.038 21.166 1.00 24.84 ? 401 PHE B CE2 1 ATOM 8605 C CZ . PHE B 1 381 ? -4.574 10.959 22.205 1.00 24.77 ? 401 PHE B CZ 1 ATOM 8606 N N . HIS B 1 382 ? -5.643 4.062 21.861 1.00 23.78 ? 402 HIS B N 1 ATOM 8607 C CA . HIS B 1 382 ? -5.442 2.684 21.385 1.00 23.74 ? 402 HIS B CA 1 ATOM 8608 C C . HIS B 1 382 ? -4.859 2.704 19.984 1.00 24.13 ? 402 HIS B C 1 ATOM 8609 O O . HIS B 1 382 ? -5.227 3.549 19.170 1.00 23.73 ? 402 HIS B O 1 ATOM 8610 C CB . HIS B 1 382 ? -6.750 1.890 21.340 1.00 23.41 ? 402 HIS B CB 1 ATOM 8611 C CG . HIS B 1 382 ? -7.343 1.610 22.684 1.00 23.22 ? 402 HIS B CG 1 ATOM 8612 N ND1 . HIS B 1 382 ? -6.681 0.895 23.656 1.00 22.46 ? 402 HIS B ND1 1 ATOM 8613 C CD2 . HIS B 1 382 ? -8.551 1.930 23.209 1.00 22.91 ? 402 HIS B CD2 1 ATOM 8614 C CE1 . HIS B 1 382 ? -7.442 0.811 24.733 1.00 23.28 ? 402 HIS B CE1 1 ATOM 8615 N NE2 . HIS B 1 382 ? -8.585 1.428 24.486 1.00 23.11 ? 402 HIS B NE2 1 ATOM 8616 N N . TYR B 1 383 ? -3.944 1.773 19.715 1.00 24.68 ? 403 TYR B N 1 ATOM 8617 C CA . TYR B 1 383 ? -3.510 1.475 18.350 1.00 24.95 ? 403 TYR B CA 1 ATOM 8618 C C . TYR B 1 383 ? -3.806 -0.005 18.086 1.00 24.83 ? 403 TYR B C 1 ATOM 8619 O O . TYR B 1 383 ? -3.024 -0.889 18.445 1.00 24.33 ? 403 TYR B O 1 ATOM 8620 C CB . TYR B 1 383 ? -2.024 1.800 18.161 1.00 25.52 ? 403 TYR B CB 1 ATOM 8621 C CG . TYR B 1 383 ? -1.526 1.621 16.736 1.00 27.68 ? 403 TYR B CG 1 ATOM 8622 C CD1 . TYR B 1 383 ? -1.458 2.701 15.859 1.00 30.40 ? 403 TYR B CD1 1 ATOM 8623 C CD2 . TYR B 1 383 ? -1.132 0.373 16.266 1.00 29.65 ? 403 TYR B CD2 1 ATOM 8624 C CE1 . TYR B 1 383 ? -1.005 2.540 14.549 1.00 31.92 ? 403 TYR B CE1 1 ATOM 8625 C CE2 . TYR B 1 383 ? -0.677 0.201 14.966 1.00 31.20 ? 403 TYR B CE2 1 ATOM 8626 C CZ . TYR B 1 383 ? -0.621 1.285 14.113 1.00 32.83 ? 403 TYR B CZ 1 ATOM 8627 O OH . TYR B 1 383 ? -0.179 1.107 12.824 1.00 35.93 ? 403 TYR B OH 1 ATOM 8628 N N . TYR B 1 384 ? -4.968 -0.260 17.495 1.00 25.07 ? 404 TYR B N 1 ATOM 8629 C CA . TYR B 1 384 ? -5.424 -1.608 17.193 1.00 25.38 ? 404 TYR B CA 1 ATOM 8630 C C . TYR B 1 384 ? -6.177 -1.530 15.865 1.00 25.71 ? 404 TYR B C 1 ATOM 8631 O O . TYR B 1 384 ? -7.204 -0.862 15.789 1.00 25.10 ? 404 TYR B O 1 ATOM 8632 C CB . TYR B 1 384 ? -6.347 -2.136 18.319 1.00 25.59 ? 404 TYR B CB 1 ATOM 8633 C CG . TYR B 1 384 ? -6.912 -3.522 18.062 1.00 26.13 ? 404 TYR B CG 1 ATOM 8634 C CD1 . TYR B 1 384 ? -6.406 -4.649 18.714 1.00 28.09 ? 404 TYR B CD1 1 ATOM 8635 C CD2 . TYR B 1 384 ? -7.937 -3.710 17.150 1.00 27.71 ? 404 TYR B CD2 1 ATOM 8636 C CE1 . TYR B 1 384 ? -6.930 -5.935 18.453 1.00 28.59 ? 404 TYR B CE1 1 ATOM 8637 C CE2 . TYR B 1 384 ? -8.458 -4.978 16.878 1.00 27.95 ? 404 TYR B CE2 1 ATOM 8638 C CZ . TYR B 1 384 ? -7.964 -6.080 17.527 1.00 28.93 ? 404 TYR B CZ 1 ATOM 8639 O OH . TYR B 1 384 ? -8.510 -7.319 17.218 1.00 29.38 ? 404 TYR B OH 1 ATOM 8640 N N . ASP B 1 385 ? -5.674 -2.223 14.842 1.00 25.94 ? 405 ASP B N 1 ATOM 8641 C CA . ASP B 1 385 ? -6.235 -2.158 13.483 1.00 26.85 ? 405 ASP B CA 1 ATOM 8642 C C . ASP B 1 385 ? -6.508 -0.701 13.056 1.00 27.22 ? 405 ASP B C 1 ATOM 8643 O O . ASP B 1 385 ? -7.629 -0.336 12.709 1.00 27.18 ? 405 ASP B O 1 ATOM 8644 C CB . ASP B 1 385 ? -7.513 -3.013 13.379 1.00 26.95 ? 405 ASP B CB 1 ATOM 8645 C CG . ASP B 1 385 ? -8.019 -3.150 11.946 1.00 27.99 ? 405 ASP B CG 1 ATOM 8646 O OD1 . ASP B 1 385 ? -7.202 -3.015 11.002 1.00 30.03 ? 405 ASP B OD1 1 ATOM 8647 O OD2 . ASP B 1 385 ? -9.233 -3.400 11.758 1.00 28.56 ? 405 ASP B OD2 1 ATOM 8648 N N . ALA B 1 386 ? -5.468 0.125 13.102 1.00 27.78 ? 406 ALA B N 1 ATOM 8649 C CA . ALA B 1 386 ? -5.613 1.549 12.855 1.00 28.23 ? 406 ALA B CA 1 ATOM 8650 C C . ALA B 1 386 ? -4.418 2.100 12.091 1.00 28.52 ? 406 ALA B C 1 ATOM 8651 O O . ALA B 1 386 ? -3.329 1.532 12.125 1.00 28.70 ? 406 ALA B O 1 ATOM 8652 C CB . ALA B 1 386 ? -5.779 2.289 14.172 1.00 28.30 ? 406 ALA B CB 1 ATOM 8653 N N . ASP B 1 387 ? -4.636 3.219 11.410 1.00 28.74 ? 407 ASP B N 1 ATOM 8654 C CA . ASP B 1 387 ? -3.579 3.872 10.651 1.00 28.69 ? 407 ASP B CA 1 ATOM 8655 C C . ASP B 1 387 ? -2.729 4.749 11.569 1.00 28.85 ? 407 ASP B C 1 ATOM 8656 O O . ASP B 1 387 ? -1.527 4.894 11.347 1.00 29.13 ? 407 ASP B O 1 ATOM 8657 C CB . ASP B 1 387 ? -4.174 4.696 9.497 1.00 28.66 ? 407 ASP B CB 1 ATOM 8658 C CG . ASP B 1 387 ? -4.660 3.831 8.346 1.00 28.29 ? 407 ASP B CG 1 ATOM 8659 O OD1 . ASP B 1 387 ? -4.469 2.604 8.389 1.00 28.19 ? 407 ASP B OD1 1 ATOM 8660 O OD2 . ASP B 1 387 ? -5.225 4.376 7.381 1.00 28.67 ? 407 ASP B OD2 1 ATOM 8661 N N . ASP B 1 388 ? -3.367 5.323 12.587 1.00 28.79 ? 408 ASP B N 1 ATOM 8662 C CA . ASP B 1 388 ? -2.716 6.155 13.603 1.00 28.81 ? 408 ASP B CA 1 ATOM 8663 C C . ASP B 1 388 ? -3.283 5.791 14.978 1.00 28.31 ? 408 ASP B C 1 ATOM 8664 O O . ASP B 1 388 ? -4.324 5.135 15.055 1.00 28.59 ? 408 ASP B O 1 ATOM 8665 C CB . ASP B 1 388 ? -2.995 7.628 13.317 1.00 28.89 ? 408 ASP B CB 1 ATOM 8666 C CG . ASP B 1 388 ? -2.507 8.053 11.957 1.00 30.29 ? 408 ASP B CG 1 ATOM 8667 O OD1 . ASP B 1 388 ? -1.278 8.057 11.756 1.00 32.82 ? 408 ASP B OD1 1 ATOM 8668 O OD2 . ASP B 1 388 ? -3.342 8.378 11.090 1.00 32.92 ? 408 ASP B OD2 1 ATOM 8669 N N . PRO B 1 389 ? -2.611 6.218 16.065 1.00 27.65 ? 409 PRO B N 1 ATOM 8670 C CA . PRO B 1 389 ? -3.176 6.017 17.403 1.00 27.00 ? 409 PRO B CA 1 ATOM 8671 C C . PRO B 1 389 ? -4.498 6.757 17.536 1.00 26.10 ? 409 PRO B C 1 ATOM 8672 O O . PRO B 1 389 ? -4.613 7.886 17.077 1.00 25.92 ? 409 PRO B O 1 ATOM 8673 C CB . PRO B 1 389 ? -2.120 6.624 18.332 1.00 27.19 ? 409 PRO B CB 1 ATOM 8674 C CG . PRO B 1 389 ? -0.868 6.682 17.504 1.00 27.56 ? 409 PRO B CG 1 ATOM 8675 C CD . PRO B 1 389 ? -1.323 6.932 16.121 1.00 27.53 ? 409 PRO B CD 1 ATOM 8676 N N . VAL B 1 390 ? -5.492 6.114 18.138 1.00 25.30 ? 410 VAL B N 1 ATOM 8677 C CA . VAL B 1 390 ? -6.838 6.673 18.201 1.00 24.53 ? 410 VAL B CA 1 ATOM 8678 C C . VAL B 1 390 ? -7.200 7.097 19.629 1.00 24.36 ? 410 VAL B C 1 ATOM 8679 O O . VAL B 1 390 ? -7.020 6.339 20.569 1.00 23.67 ? 410 VAL B O 1 ATOM 8680 C CB . VAL B 1 390 ? -7.861 5.668 17.634 1.00 24.55 ? 410 VAL B CB 1 ATOM 8681 C CG1 . VAL B 1 390 ? -9.276 6.236 17.695 1.00 23.04 ? 410 VAL B CG1 1 ATOM 8682 C CG2 . VAL B 1 390 ? -7.470 5.291 16.182 1.00 23.33 ? 410 VAL B CG2 1 ATOM 8683 N N . HIS B 1 391 ? -7.693 8.329 19.767 1.00 24.48 ? 411 HIS B N 1 ATOM 8684 C CA . HIS B 1 391 ? -8.159 8.872 21.050 1.00 24.43 ? 411 HIS B CA 1 ATOM 8685 C C . HIS B 1 391 ? -9.536 8.287 21.382 1.00 24.35 ? 411 HIS B C 1 ATOM 8686 O O . HIS B 1 391 ? -10.461 8.363 20.568 1.00 24.41 ? 411 HIS B O 1 ATOM 8687 C CB . HIS B 1 391 ? -8.250 10.398 20.961 1.00 24.46 ? 411 HIS B CB 1 ATOM 8688 C CG . HIS B 1 391 ? -8.679 11.066 22.232 1.00 25.40 ? 411 HIS B CG 1 ATOM 8689 N ND1 . HIS B 1 391 ? -9.925 11.625 22.390 1.00 25.94 ? 411 HIS B ND1 1 ATOM 8690 C CD2 . HIS B 1 391 ? -8.022 11.278 23.397 1.00 26.33 ? 411 HIS B CD2 1 ATOM 8691 C CE1 . HIS B 1 391 ? -10.026 12.140 23.602 1.00 27.13 ? 411 HIS B CE1 1 ATOM 8692 N NE2 . HIS B 1 391 ? -8.881 11.947 24.233 1.00 26.15 ? 411 HIS B NE2 1 ATOM 8693 N N . TYR B 1 392 ? -9.661 7.697 22.568 1.00 23.97 ? 412 TYR B N 1 ATOM 8694 C CA . TYR B 1 392 ? -10.945 7.183 23.046 1.00 23.76 ? 412 TYR B CA 1 ATOM 8695 C C . TYR B 1 392 ? -11.407 8.019 24.228 1.00 23.61 ? 412 TYR B C 1 ATOM 8696 O O . TYR B 1 392 ? -10.862 7.880 25.324 1.00 23.67 ? 412 TYR B O 1 ATOM 8697 C CB . TYR B 1 392 ? -10.809 5.717 23.459 1.00 24.08 ? 412 TYR B CB 1 ATOM 8698 C CG . TYR B 1 392 ? -10.881 4.765 22.294 1.00 23.29 ? 412 TYR B CG 1 ATOM 8699 C CD1 . TYR B 1 392 ? -9.881 4.751 21.315 1.00 24.77 ? 412 TYR B CD1 1 ATOM 8700 C CD2 . TYR B 1 392 ? -11.953 3.895 22.150 1.00 23.53 ? 412 TYR B CD2 1 ATOM 8701 C CE1 . TYR B 1 392 ? -9.949 3.883 20.225 1.00 24.09 ? 412 TYR B CE1 1 ATOM 8702 C CE2 . TYR B 1 392 ? -12.037 3.032 21.068 1.00 24.27 ? 412 TYR B CE2 1 ATOM 8703 C CZ . TYR B 1 392 ? -11.033 3.026 20.112 1.00 24.58 ? 412 TYR B CZ 1 ATOM 8704 O OH . TYR B 1 392 ? -11.125 2.166 19.053 1.00 23.85 ? 412 TYR B OH 1 ATOM 8705 N N . PRO B 1 393 ? -12.406 8.900 24.018 1.00 23.12 ? 413 PRO B N 1 ATOM 8706 C CA . PRO B 1 393 ? -12.876 9.739 25.130 1.00 23.01 ? 413 PRO B CA 1 ATOM 8707 C C . PRO B 1 393 ? -13.652 8.953 26.190 1.00 22.51 ? 413 PRO B C 1 ATOM 8708 O O . PRO B 1 393 ? -14.436 8.065 25.847 1.00 22.34 ? 413 PRO B O 1 ATOM 8709 C CB . PRO B 1 393 ? -13.789 10.760 24.443 1.00 22.75 ? 413 PRO B CB 1 ATOM 8710 C CG . PRO B 1 393 ? -14.293 10.067 23.246 1.00 23.38 ? 413 PRO B CG 1 ATOM 8711 C CD . PRO B 1 393 ? -13.204 9.115 22.799 1.00 23.55 ? 413 PRO B CD 1 ATOM 8712 N N . ARG B 1 394 ? -13.409 9.270 27.459 1.00 22.22 ? 414 ARG B N 1 ATOM 8713 C CA . ARG B 1 394 ? -14.118 8.647 28.575 1.00 21.95 ? 414 ARG B CA 1 ATOM 8714 C C . ARG B 1 394 ? -14.151 7.118 28.439 1.00 21.76 ? 414 ARG B C 1 ATOM 8715 O O . ARG B 1 394 ? -15.226 6.506 28.479 1.00 21.54 ? 414 ARG B O 1 ATOM 8716 C CB . ARG B 1 394 ? -15.552 9.187 28.652 1.00 22.04 ? 414 ARG B CB 1 ATOM 8717 C CG . ARG B 1 394 ? -15.678 10.708 28.687 1.00 23.06 ? 414 ARG B CG 1 ATOM 8718 C CD . ARG B 1 394 ? -17.154 11.079 28.850 1.00 25.07 ? 414 ARG B CD 1 ATOM 8719 N NE . ARG B 1 394 ? -17.434 12.515 28.980 1.00 25.31 ? 414 ARG B NE 1 ATOM 8720 C CZ . ARG B 1 394 ? -18.477 13.140 28.423 1.00 26.12 ? 414 ARG B CZ 1 ATOM 8721 N NH1 . ARG B 1 394 ? -19.332 12.483 27.636 1.00 26.14 ? 414 ARG B NH1 1 ATOM 8722 N NH2 . ARG B 1 394 ? -18.656 14.442 28.620 1.00 25.76 ? 414 ARG B NH2 1 ATOM 8723 N N . ALA B 1 395 ? -12.968 6.523 28.270 1.00 21.26 ? 415 ALA B N 1 ATOM 8724 C CA . ALA B 1 395 ? -12.803 5.081 28.103 1.00 20.96 ? 415 ALA B CA 1 ATOM 8725 C C . ALA B 1 395 ? -12.910 4.340 29.436 1.00 20.93 ? 415 ALA B C 1 ATOM 8726 O O . ALA B 1 395 ? -13.344 3.183 29.480 1.00 20.88 ? 415 ALA B O 1 ATOM 8727 C CB . ALA B 1 395 ? -11.437 4.775 27.438 1.00 20.87 ? 415 ALA B CB 1 ATOM 8728 N N . LEU B 1 396 ? -12.458 4.993 30.504 1.00 20.78 ? 416 LEU B N 1 ATOM 8729 C CA . LEU B 1 396 ? -12.653 4.516 31.861 1.00 20.56 ? 416 LEU B CA 1 ATOM 8730 C C . LEU B 1 396 ? -13.255 5.627 32.701 1.00 20.31 ? 416 LEU B C 1 ATOM 8731 O O . LEU B 1 396 ? -13.229 6.793 32.309 1.00 19.95 ? 416 LEU B O 1 ATOM 8732 C CB . LEU B 1 396 ? -11.325 4.110 32.520 1.00 20.99 ? 416 LEU B CB 1 ATOM 8733 C CG . LEU B 1 396 ? -10.229 3.425 31.719 1.00 21.04 ? 416 LEU B CG 1 ATOM 8734 C CD1 . LEU B 1 396 ? -9.389 4.466 30.998 1.00 20.94 ? 416 LEU B CD1 1 ATOM 8735 C CD2 . LEU B 1 396 ? -9.359 2.573 32.645 1.00 21.69 ? 416 LEU B CD2 1 ATOM 8736 N N . CYS B 1 397 ? -13.773 5.257 33.868 1.00 20.04 ? 417 CYS B N 1 ATOM 8737 C CA . CYS B 1 397 ? -14.158 6.227 34.881 1.00 19.97 ? 417 CYS B CA 1 ATOM 8738 C C . CYS B 1 397 ? -13.766 5.728 36.270 1.00 20.13 ? 417 CYS B C 1 ATOM 8739 O O . CYS B 1 397 ? -13.683 4.520 36.522 1.00 20.90 ? 417 CYS B O 1 ATOM 8740 C CB . CYS B 1 397 ? -15.663 6.516 34.820 1.00 20.21 ? 417 CYS B CB 1 ATOM 8741 S SG . CYS B 1 397 ? -16.678 5.153 35.393 1.00 20.23 ? 417 CYS B SG 1 ATOM 8742 N N . LEU B 1 398 ? -13.534 6.671 37.167 1.00 20.21 ? 418 LEU B N 1 ATOM 8743 C CA . LEU B 1 398 ? -13.127 6.381 38.532 1.00 20.57 ? 418 LEU B CA 1 ATOM 8744 C C . LEU B 1 398 ? -14.037 7.178 39.458 1.00 20.60 ? 418 LEU B C 1 ATOM 8745 O O . LEU B 1 398 ? -14.174 8.383 39.298 1.00 20.32 ? 418 LEU B O 1 ATOM 8746 C CB . LEU B 1 398 ? -11.666 6.791 38.722 1.00 20.39 ? 418 LEU B CB 1 ATOM 8747 C CG . LEU B 1 398 ? -10.994 6.459 40.042 1.00 20.75 ? 418 LEU B CG 1 ATOM 8748 C CD1 . LEU B 1 398 ? -11.094 4.953 40.367 1.00 19.36 ? 418 LEU B CD1 1 ATOM 8749 C CD2 . LEU B 1 398 ? -9.524 6.946 39.993 1.00 21.01 ? 418 LEU B CD2 1 ATOM 8750 N N . PHE B 1 399 ? -14.685 6.514 40.412 1.00 21.02 ? 419 PHE B N 1 ATOM 8751 C CA . PHE B 1 399 ? -15.663 7.213 41.237 1.00 21.01 ? 419 PHE B CA 1 ATOM 8752 C C . PHE B 1 399 ? -15.946 6.551 42.568 1.00 21.42 ? 419 PHE B C 1 ATOM 8753 O O . PHE B 1 399 ? -15.824 5.338 42.702 1.00 21.80 ? 419 PHE B O 1 ATOM 8754 C CB . PHE B 1 399 ? -16.979 7.429 40.456 1.00 21.06 ? 419 PHE B CB 1 ATOM 8755 C CG . PHE B 1 399 ? -17.727 6.161 40.118 1.00 20.96 ? 419 PHE B CG 1 ATOM 8756 C CD1 . PHE B 1 399 ? -18.712 5.660 40.977 1.00 21.07 ? 419 PHE B CD1 1 ATOM 8757 C CD2 . PHE B 1 399 ? -17.489 5.496 38.928 1.00 20.21 ? 419 PHE B CD2 1 ATOM 8758 C CE1 . PHE B 1 399 ? -19.420 4.510 40.665 1.00 19.02 ? 419 PHE B CE1 1 ATOM 8759 C CE2 . PHE B 1 399 ? -18.186 4.334 38.612 1.00 20.24 ? 419 PHE B CE2 1 ATOM 8760 C CZ . PHE B 1 399 ? -19.160 3.844 39.483 1.00 19.84 ? 419 PHE B CZ 1 ATOM 8761 N N . GLU B 1 400 ? -16.310 7.370 43.555 1.00 21.52 ? 420 GLU B N 1 ATOM 8762 C CA . GLU B 1 400 ? -16.798 6.873 44.832 1.00 21.64 ? 420 GLU B CA 1 ATOM 8763 C C . GLU B 1 400 ? -18.320 6.960 44.822 1.00 21.84 ? 420 GLU B C 1 ATOM 8764 O O . GLU B 1 400 ? -18.887 7.940 44.347 1.00 21.49 ? 420 GLU B O 1 ATOM 8765 C CB . GLU B 1 400 ? -16.238 7.697 46.001 1.00 21.54 ? 420 GLU B CB 1 ATOM 8766 C CG . GLU B 1 400 ? -16.640 7.168 47.368 1.00 21.07 ? 420 GLU B CG 1 ATOM 8767 C CD . GLU B 1 400 ? -15.915 7.853 48.515 1.00 21.63 ? 420 GLU B CD 1 ATOM 8768 O OE1 . GLU B 1 400 ? -15.610 9.054 48.405 1.00 21.71 ? 420 GLU B OE1 1 ATOM 8769 O OE2 . GLU B 1 400 ? -15.651 7.185 49.540 1.00 23.95 ? 420 GLU B OE2 1 ATOM 8770 N N . MET B 1 401 ? -18.983 5.940 45.344 1.00 22.15 ? 421 MET B N 1 ATOM 8771 C CA . MET B 1 401 ? -20.439 5.985 45.430 1.00 23.01 ? 421 MET B CA 1 ATOM 8772 C C . MET B 1 401 ? -20.918 5.329 46.699 1.00 22.28 ? 421 MET B C 1 ATOM 8773 O O . MET B 1 401 ? -20.359 4.311 47.131 1.00 21.83 ? 421 MET B O 1 ATOM 8774 C CB . MET B 1 401 ? -21.105 5.324 44.217 1.00 23.66 ? 421 MET B CB 1 ATOM 8775 C CG . MET B 1 401 ? -20.742 3.863 44.003 1.00 26.78 ? 421 MET B CG 1 ATOM 8776 S SD . MET B 1 401 ? -21.935 3.003 42.950 1.00 31.78 ? 421 MET B SD 1 ATOM 8777 C CE . MET B 1 401 ? -23.341 2.816 44.052 1.00 33.06 ? 421 MET B CE 1 ATOM 8778 N N . PRO B 1 402 ? -21.953 5.913 47.313 1.00 21.77 ? 422 PRO B N 1 ATOM 8779 C CA . PRO B 1 402 ? -22.552 5.213 48.431 1.00 21.77 ? 422 PRO B CA 1 ATOM 8780 C C . PRO B 1 402 ? -23.179 3.881 47.994 1.00 21.47 ? 422 PRO B C 1 ATOM 8781 O O . PRO B 1 402 ? -23.819 3.796 46.945 1.00 20.95 ? 422 PRO B O 1 ATOM 8782 C CB . PRO B 1 402 ? -23.592 6.207 48.975 1.00 21.41 ? 422 PRO B CB 1 ATOM 8783 C CG . PRO B 1 402 ? -23.773 7.210 47.974 1.00 22.10 ? 422 PRO B CG 1 ATOM 8784 C CD . PRO B 1 402 ? -22.583 7.215 47.060 1.00 21.91 ? 422 PRO B CD 1 ATOM 8785 N N . THR B 1 403 ? -22.931 2.845 48.786 1.00 21.96 ? 423 THR B N 1 ATOM 8786 C CA . THR B 1 403 ? -23.477 1.508 48.545 1.00 22.10 ? 423 THR B CA 1 ATOM 8787 C C . THR B 1 403 ? -24.923 1.380 49.032 1.00 22.28 ? 423 THR B C 1 ATOM 8788 O O . THR B 1 403 ? -25.618 0.446 48.678 1.00 22.47 ? 423 THR B O 1 ATOM 8789 C CB . THR B 1 403 ? -22.671 0.464 49.291 1.00 21.73 ? 423 THR B CB 1 ATOM 8790 O OG1 . THR B 1 403 ? -22.718 0.761 50.695 1.00 21.56 ? 423 THR B OG1 1 ATOM 8791 C CG2 . THR B 1 403 ? -21.220 0.448 48.801 1.00 22.39 ? 423 THR B CG2 1 ATOM 8792 N N . GLY B 1 404 ? -25.351 2.301 49.880 1.00 22.84 ? 424 GLY B N 1 ATOM 8793 C CA . GLY B 1 404 ? -26.692 2.266 50.433 1.00 23.23 ? 424 GLY B CA 1 ATOM 8794 C C . GLY B 1 404 ? -26.843 1.265 51.561 1.00 23.44 ? 424 GLY B C 1 ATOM 8795 O O . GLY B 1 404 ? -27.962 0.964 51.958 1.00 24.53 ? 424 GLY B O 1 ATOM 8796 N N . VAL B 1 405 ? -25.735 0.720 52.061 1.00 23.08 ? 425 VAL B N 1 ATOM 8797 C CA . VAL B 1 405 ? -25.772 -0.168 53.221 1.00 22.80 ? 425 VAL B CA 1 ATOM 8798 C C . VAL B 1 405 ? -24.524 0.109 54.071 1.00 22.34 ? 425 VAL B C 1 ATOM 8799 O O . VAL B 1 405 ? -23.421 0.164 53.537 1.00 22.55 ? 425 VAL B O 1 ATOM 8800 C CB . VAL B 1 405 ? -25.888 -1.669 52.815 1.00 23.07 ? 425 VAL B CB 1 ATOM 8801 C CG1 . VAL B 1 405 ? -24.668 -2.135 52.036 1.00 22.26 ? 425 VAL B CG1 1 ATOM 8802 C CG2 . VAL B 1 405 ? -26.106 -2.549 54.056 1.00 23.50 ? 425 VAL B CG2 1 ATOM 8803 N N . PRO B 1 406 ? -24.699 0.329 55.388 1.00 21.78 ? 426 PRO B N 1 ATOM 8804 C CA . PRO B 1 406 ? -23.552 0.749 56.174 1.00 21.68 ? 426 PRO B CA 1 ATOM 8805 C C . PRO B 1 406 ? -22.456 -0.288 56.126 1.00 21.41 ? 426 PRO B C 1 ATOM 8806 O O . PRO B 1 406 ? -22.748 -1.485 56.011 1.00 21.21 ? 426 PRO B O 1 ATOM 8807 C CB . PRO B 1 406 ? -24.113 0.898 57.596 1.00 21.84 ? 426 PRO B CB 1 ATOM 8808 C CG . PRO B 1 406 ? -25.455 0.253 57.582 1.00 21.98 ? 426 PRO B CG 1 ATOM 8809 C CD . PRO B 1 406 ? -25.939 0.301 56.184 1.00 22.02 ? 426 PRO B CD 1 ATOM 8810 N N . LEU B 1 407 ? -21.203 0.150 56.184 1.00 21.19 ? 427 LEU B N 1 ATOM 8811 C CA . LEU B 1 407 ? -20.103 -0.808 56.243 1.00 21.39 ? 427 LEU B CA 1 ATOM 8812 C C . LEU B 1 407 ? -20.205 -1.613 57.545 1.00 21.38 ? 427 LEU B C 1 ATOM 8813 O O . LEU B 1 407 ? -19.926 -2.815 57.573 1.00 21.42 ? 427 LEU B O 1 ATOM 8814 C CB . LEU B 1 407 ? -18.743 -0.111 56.122 1.00 21.56 ? 427 LEU B CB 1 ATOM 8815 C CG . LEU B 1 407 ? -17.565 -1.093 56.009 1.00 21.59 ? 427 LEU B CG 1 ATOM 8816 C CD1 . LEU B 1 407 ? -16.403 -0.499 55.194 1.00 21.56 ? 427 LEU B CD1 1 ATOM 8817 C CD2 . LEU B 1 407 ? -17.091 -1.543 57.389 1.00 21.37 ? 427 LEU B CD2 1 ATOM 8818 N N . ARG B 1 408 ? -20.603 -0.936 58.618 1.00 21.14 ? 428 ARG B N 1 ATOM 8819 C CA . ARG B 1 408 ? -20.916 -1.591 59.882 1.00 21.30 ? 428 ARG B CA 1 ATOM 8820 C C . ARG B 1 408 ? -21.857 -0.708 60.673 1.00 21.21 ? 428 ARG B C 1 ATOM 8821 O O . ARG B 1 408 ? -21.833 0.510 60.528 1.00 20.88 ? 428 ARG B O 1 ATOM 8822 C CB . ARG B 1 408 ? -19.650 -1.856 60.701 1.00 21.32 ? 428 ARG B CB 1 ATOM 8823 C CG . ARG B 1 408 ? -18.753 -0.630 60.908 1.00 22.56 ? 428 ARG B CG 1 ATOM 8824 C CD . ARG B 1 408 ? -17.580 -0.967 61.816 1.00 23.78 ? 428 ARG B CD 1 ATOM 8825 N NE . ARG B 1 408 ? -16.364 -0.271 61.407 1.00 24.64 ? 428 ARG B NE 1 ATOM 8826 C CZ . ARG B 1 408 ? -16.063 0.994 61.690 1.00 26.42 ? 428 ARG B CZ 1 ATOM 8827 N NH1 . ARG B 1 408 ? -16.881 1.755 62.403 1.00 28.11 ? 428 ARG B NH1 1 ATOM 8828 N NH2 . ARG B 1 408 ? -14.923 1.508 61.244 1.00 27.10 ? 428 ARG B NH2 1 ATOM 8829 N N . ARG B 1 409 ? -22.699 -1.333 61.493 1.00 21.17 ? 429 ARG B N 1 ATOM 8830 C CA . ARG B 1 409 ? -23.591 -0.597 62.382 1.00 20.82 ? 429 ARG B CA 1 ATOM 8831 C C . ARG B 1 409 ? -23.986 -1.485 63.545 1.00 21.13 ? 429 ARG B C 1 ATOM 8832 O O . ARG B 1 409 ? -23.971 -2.710 63.423 1.00 21.02 ? 429 ARG B O 1 ATOM 8833 C CB . ARG B 1 409 ? -24.821 -0.074 61.637 1.00 20.61 ? 429 ARG B CB 1 ATOM 8834 C CG . ARG B 1 409 ? -25.787 -1.140 61.140 1.00 20.13 ? 429 ARG B CG 1 ATOM 8835 C CD . ARG B 1 409 ? -26.837 -1.493 62.184 1.00 20.58 ? 429 ARG B CD 1 ATOM 8836 N NE . ARG B 1 409 ? -27.877 -0.473 62.286 1.00 20.25 ? 429 ARG B NE 1 ATOM 8837 C CZ . ARG B 1 409 ? -28.909 -0.534 63.117 1.00 20.70 ? 429 ARG B CZ 1 ATOM 8838 N NH1 . ARG B 1 409 ? -29.049 -1.555 63.966 1.00 19.88 ? 429 ARG B NH1 1 ATOM 8839 N NH2 . ARG B 1 409 ? -29.802 0.448 63.113 1.00 22.89 ? 429 ARG B NH2 1 ATOM 8840 N N . HIS B 1 410 ? -24.317 -0.857 64.673 1.00 21.10 ? 430 HIS B N 1 ATOM 8841 C CA . HIS B 1 410 ? -24.777 -1.569 65.849 1.00 20.87 ? 430 HIS B CA 1 ATOM 8842 C C . HIS B 1 410 ? -25.655 -0.694 66.732 1.00 21.12 ? 430 HIS B C 1 ATOM 8843 O O . HIS B 1 410 ? -25.285 0.440 67.051 1.00 20.80 ? 430 HIS B O 1 ATOM 8844 C CB . HIS B 1 410 ? -23.600 -2.067 66.683 1.00 21.07 ? 430 HIS B CB 1 ATOM 8845 C CG . HIS B 1 410 ? -24.017 -2.752 67.941 1.00 19.67 ? 430 HIS B CG 1 ATOM 8846 N ND1 . HIS B 1 410 ? -24.693 -3.951 67.940 1.00 21.58 ? 430 HIS B ND1 1 ATOM 8847 C CD2 . HIS B 1 410 ? -23.884 -2.397 69.240 1.00 19.58 ? 430 HIS B CD2 1 ATOM 8848 C CE1 . HIS B 1 410 ? -24.946 -4.315 69.186 1.00 21.23 ? 430 HIS B CE1 1 ATOM 8849 N NE2 . HIS B 1 410 ? -24.460 -3.391 69.995 1.00 19.59 ? 430 HIS B NE2 1 ATOM 8850 N N . PHE B 1 411 ? -26.803 -1.241 67.138 1.00 20.96 ? 431 PHE B N 1 ATOM 8851 C CA . PHE B 1 411 ? -27.665 -0.603 68.115 1.00 21.24 ? 431 PHE B CA 1 ATOM 8852 C C . PHE B 1 411 ? -27.450 -1.321 69.446 1.00 21.70 ? 431 PHE B C 1 ATOM 8853 O O . PHE B 1 411 ? -27.832 -2.477 69.596 1.00 21.49 ? 431 PHE B O 1 ATOM 8854 C CB . PHE B 1 411 ? -29.127 -0.682 67.678 1.00 21.27 ? 431 PHE B CB 1 ATOM 8855 C CG . PHE B 1 411 ? -30.061 0.020 68.599 1.00 20.96 ? 431 PHE B CG 1 ATOM 8856 C CD1 . PHE B 1 411 ? -30.652 -0.656 69.660 1.00 21.97 ? 431 PHE B CD1 1 ATOM 8857 C CD2 . PHE B 1 411 ? -30.318 1.377 68.439 1.00 21.17 ? 431 PHE B CD2 1 ATOM 8858 C CE1 . PHE B 1 411 ? -31.508 0.005 70.532 1.00 21.46 ? 431 PHE B CE1 1 ATOM 8859 C CE2 . PHE B 1 411 ? -31.180 2.045 69.295 1.00 21.38 ? 431 PHE B CE2 1 ATOM 8860 C CZ . PHE B 1 411 ? -31.775 1.357 70.348 1.00 21.38 ? 431 PHE B CZ 1 ATOM 8861 N N . ASN B 1 412 ? -26.797 -0.641 70.391 1.00 22.29 ? 432 ASN B N 1 ATOM 8862 C CA . ASN B 1 412 ? -26.485 -1.222 71.696 1.00 22.81 ? 432 ASN B CA 1 ATOM 8863 C C . ASN B 1 412 ? -27.597 -0.882 72.671 1.00 23.40 ? 432 ASN B C 1 ATOM 8864 O O . ASN B 1 412 ? -27.555 0.136 73.350 1.00 23.96 ? 432 ASN B O 1 ATOM 8865 C CB . ASN B 1 412 ? -25.136 -0.705 72.217 1.00 22.54 ? 432 ASN B CB 1 ATOM 8866 C CG . ASN B 1 412 ? -24.524 -1.628 73.240 1.00 22.70 ? 432 ASN B CG 1 ATOM 8867 O OD1 . ASN B 1 412 ? -24.479 -1.321 74.430 1.00 23.47 ? 432 ASN B OD1 1 ATOM 8868 N ND2 . ASN B 1 412 ? -24.063 -2.777 72.787 1.00 21.24 ? 432 ASN B ND2 1 ATOM 8869 N N . SER B 1 413 ? -28.611 -1.728 72.705 1.00 24.34 ? 433 SER B N 1 ATOM 8870 C CA . SER B 1 413 ? -29.783 -1.502 73.538 1.00 25.12 ? 433 SER B CA 1 ATOM 8871 C C . SER B 1 413 ? -29.450 -1.619 75.016 1.00 25.88 ? 433 SER B C 1 ATOM 8872 O O . SER B 1 413 ? -28.565 -2.388 75.396 1.00 25.07 ? 433 SER B O 1 ATOM 8873 C CB . SER B 1 413 ? -30.846 -2.536 73.196 1.00 25.14 ? 433 SER B CB 1 ATOM 8874 O OG . SER B 1 413 ? -31.943 -2.432 74.067 1.00 26.16 ? 433 SER B OG 1 ATOM 8875 N N . ASN B 1 414 ? -30.164 -0.860 75.849 1.00 27.03 ? 434 ASN B N 1 ATOM 8876 C CA . ASN B 1 414 ? -30.096 -1.072 77.297 1.00 28.29 ? 434 ASN B CA 1 ATOM 8877 C C . ASN B 1 414 ? -31.214 -1.999 77.793 1.00 29.33 ? 434 ASN B C 1 ATOM 8878 O O . ASN B 1 414 ? -31.284 -2.315 78.979 1.00 29.95 ? 434 ASN B O 1 ATOM 8879 C CB . ASN B 1 414 ? -30.056 0.265 78.064 1.00 28.21 ? 434 ASN B CB 1 ATOM 8880 C CG . ASN B 1 414 ? -31.387 1.012 78.063 1.00 28.19 ? 434 ASN B CG 1 ATOM 8881 O OD1 . ASN B 1 414 ? -32.425 0.515 77.594 1.00 26.08 ? 434 ASN B OD1 1 ATOM 8882 N ND2 . ASN B 1 414 ? -31.355 2.235 78.592 1.00 27.81 ? 434 ASN B ND2 1 ATOM 8883 N N . PHE B 1 415 ? -32.087 -2.418 76.872 1.00 30.41 ? 435 PHE B N 1 ATOM 8884 C CA . PHE B 1 415 ? -33.177 -3.363 77.152 1.00 31.11 ? 435 PHE B CA 1 ATOM 8885 C C . PHE B 1 415 ? -34.195 -2.834 78.178 1.00 31.32 ? 435 PHE B C 1 ATOM 8886 O O . PHE B 1 415 ? -34.955 -3.611 78.753 1.00 31.64 ? 435 PHE B O 1 ATOM 8887 C CB . PHE B 1 415 ? -32.613 -4.730 77.593 1.00 31.24 ? 435 PHE B CB 1 ATOM 8888 C CG . PHE B 1 415 ? -31.519 -5.244 76.699 1.00 32.12 ? 435 PHE B CG 1 ATOM 8889 C CD1 . PHE B 1 415 ? -30.201 -5.276 77.134 1.00 32.17 ? 435 PHE B CD1 1 ATOM 8890 C CD2 . PHE B 1 415 ? -31.805 -5.661 75.404 1.00 32.66 ? 435 PHE B CD2 1 ATOM 8891 C CE1 . PHE B 1 415 ? -29.187 -5.725 76.301 1.00 32.18 ? 435 PHE B CE1 1 ATOM 8892 C CE2 . PHE B 1 415 ? -30.799 -6.112 74.569 1.00 32.96 ? 435 PHE B CE2 1 ATOM 8893 C CZ . PHE B 1 415 ? -29.487 -6.143 75.016 1.00 32.59 ? 435 PHE B CZ 1 ATOM 8894 N N . LYS B 1 416 ? -34.195 -1.519 78.397 1.00 31.44 ? 436 LYS B N 1 ATOM 8895 C CA . LYS B 1 416 ? -35.129 -0.836 79.310 1.00 31.33 ? 436 LYS B CA 1 ATOM 8896 C C . LYS B 1 416 ? -35.670 0.394 78.595 1.00 30.43 ? 436 LYS B C 1 ATOM 8897 O O . LYS B 1 416 ? -35.717 1.489 79.167 1.00 30.61 ? 436 LYS B O 1 ATOM 8898 C CB . LYS B 1 416 ? -34.400 -0.379 80.576 1.00 31.71 ? 436 LYS B CB 1 ATOM 8899 C CG . LYS B 1 416 ? -33.905 -1.493 81.469 1.00 33.98 ? 436 LYS B CG 1 ATOM 8900 C CD . LYS B 1 416 ? -32.499 -1.221 82.004 1.00 36.15 ? 436 LYS B CD 1 ATOM 8901 C CE . LYS B 1 416 ? -32.377 0.104 82.727 1.00 37.78 ? 436 LYS B CE 1 ATOM 8902 N NZ . LYS B 1 416 ? -30.963 0.334 83.162 1.00 38.88 ? 436 LYS B NZ 1 ATOM 8903 N N . GLY B 1 417 ? -36.019 0.226 77.325 1.00 29.45 ? 437 GLY B N 1 ATOM 8904 C CA . GLY B 1 417 ? -36.599 1.295 76.534 1.00 28.71 ? 437 GLY B CA 1 ATOM 8905 C C . GLY B 1 417 ? -35.616 2.296 75.967 1.00 28.16 ? 437 GLY B C 1 ATOM 8906 O O . GLY B 1 417 ? -36.032 3.311 75.414 1.00 28.00 ? 437 GLY B O 1 ATOM 8907 N N . GLY B 1 418 ? -34.319 2.017 76.067 1.00 27.65 ? 438 GLY B N 1 ATOM 8908 C CA . GLY B 1 418 ? -33.306 2.941 75.567 1.00 27.12 ? 438 GLY B CA 1 ATOM 8909 C C . GLY B 1 418 ? -32.046 2.283 75.042 1.00 26.70 ? 438 GLY B C 1 ATOM 8910 O O . GLY B 1 418 ? -32.055 1.118 74.651 1.00 27.00 ? 438 GLY B O 1 ATOM 8911 N N . PHE B 1 419 ? -30.955 3.038 75.048 1.00 26.13 ? 439 PHE B N 1 ATOM 8912 C CA . PHE B 1 419 ? -29.710 2.588 74.438 1.00 25.87 ? 439 PHE B CA 1 ATOM 8913 C C . PHE B 1 419 ? -28.472 3.081 75.173 1.00 25.50 ? 439 PHE B C 1 ATOM 8914 O O . PHE B 1 419 ? -28.526 4.050 75.929 1.00 25.52 ? 439 PHE B O 1 ATOM 8915 C CB . PHE B 1 419 ? -29.685 2.945 72.939 1.00 25.71 ? 439 PHE B CB 1 ATOM 8916 C CG . PHE B 1 419 ? -29.308 4.379 72.611 1.00 26.50 ? 439 PHE B CG 1 ATOM 8917 C CD1 . PHE B 1 419 ? -28.483 4.640 71.519 1.00 27.15 ? 439 PHE B CD1 1 ATOM 8918 C CD2 . PHE B 1 419 ? -29.805 5.462 73.329 1.00 27.39 ? 439 PHE B CD2 1 ATOM 8919 C CE1 . PHE B 1 419 ? -28.136 5.943 71.168 1.00 27.39 ? 439 PHE B CE1 1 ATOM 8920 C CE2 . PHE B 1 419 ? -29.452 6.776 72.989 1.00 27.86 ? 439 PHE B CE2 1 ATOM 8921 C CZ . PHE B 1 419 ? -28.619 7.013 71.907 1.00 28.02 ? 439 PHE B CZ 1 ATOM 8922 N N . ASN B 1 420 ? -27.374 2.364 74.976 1.00 25.49 ? 440 ASN B N 1 ATOM 8923 C CA . ASN B 1 420 ? -26.058 2.771 75.469 1.00 25.38 ? 440 ASN B CA 1 ATOM 8924 C C . ASN B 1 420 ? -25.320 3.566 74.415 1.00 25.33 ? 440 ASN B C 1 ATOM 8925 O O . ASN B 1 420 ? -24.584 4.503 74.741 1.00 25.58 ? 440 ASN B O 1 ATOM 8926 C CB . ASN B 1 420 ? -25.233 1.552 75.846 1.00 25.15 ? 440 ASN B CB 1 ATOM 8927 C CG . ASN B 1 420 ? -25.913 0.698 76.889 1.00 27.00 ? 440 ASN B CG 1 ATOM 8928 O OD1 . ASN B 1 420 ? -26.492 1.220 77.840 1.00 28.12 ? 440 ASN B OD1 1 ATOM 8929 N ND2 . ASN B 1 420 ? -25.860 -0.621 76.713 1.00 27.19 ? 440 ASN B ND2 1 ATOM 8930 N N . PHE B 1 421 ? -25.486 3.150 73.156 1.00 24.76 ? 441 PHE B N 1 ATOM 8931 C CA . PHE B 1 421 ? -25.035 3.915 71.998 1.00 24.41 ? 441 PHE B CA 1 ATOM 8932 C C . PHE B 1 421 ? -25.573 3.315 70.703 1.00 24.02 ? 441 PHE B C 1 ATOM 8933 O O . PHE B 1 421 ? -26.021 2.166 70.676 1.00 23.63 ? 441 PHE B O 1 ATOM 8934 C CB . PHE B 1 421 ? -23.491 4.008 71.922 1.00 24.07 ? 441 PHE B CB 1 ATOM 8935 C CG . PHE B 1 421 ? -22.810 2.686 71.719 1.00 24.68 ? 441 PHE B CG 1 ATOM 8936 C CD1 . PHE B 1 421 ? -22.497 1.875 72.804 1.00 24.94 ? 441 PHE B CD1 1 ATOM 8937 C CD2 . PHE B 1 421 ? -22.480 2.246 70.437 1.00 26.04 ? 441 PHE B CD2 1 ATOM 8938 C CE1 . PHE B 1 421 ? -21.886 0.655 72.614 1.00 26.02 ? 441 PHE B CE1 1 ATOM 8939 C CE2 . PHE B 1 421 ? -21.853 1.027 70.246 1.00 25.15 ? 441 PHE B CE2 1 ATOM 8940 C CZ . PHE B 1 421 ? -21.557 0.230 71.332 1.00 25.69 ? 441 PHE B CZ 1 ATOM 8941 N N . TYR B 1 422 ? -25.563 4.131 69.650 1.00 23.84 ? 442 TYR B N 1 ATOM 8942 C CA . TYR B 1 422 ? -25.645 3.659 68.272 1.00 23.56 ? 442 TYR B CA 1 ATOM 8943 C C . TYR B 1 422 ? -24.334 4.050 67.600 1.00 23.74 ? 442 TYR B C 1 ATOM 8944 O O . TYR B 1 422 ? -23.886 5.188 67.743 1.00 24.03 ? 442 TYR B O 1 ATOM 8945 C CB . TYR B 1 422 ? -26.820 4.290 67.512 1.00 23.71 ? 442 TYR B CB 1 ATOM 8946 C CG . TYR B 1 422 ? -26.685 4.092 66.018 1.00 23.52 ? 442 TYR B CG 1 ATOM 8947 C CD1 . TYR B 1 422 ? -27.157 2.933 65.408 1.00 24.10 ? 442 TYR B CD1 1 ATOM 8948 C CD2 . TYR B 1 422 ? -26.030 5.033 65.225 1.00 23.66 ? 442 TYR B CD2 1 ATOM 8949 C CE1 . TYR B 1 422 ? -27.010 2.728 64.045 1.00 24.56 ? 442 TYR B CE1 1 ATOM 8950 C CE2 . TYR B 1 422 ? -25.876 4.840 63.866 1.00 24.85 ? 442 TYR B CE2 1 ATOM 8951 C CZ . TYR B 1 422 ? -26.369 3.679 63.276 1.00 25.41 ? 442 TYR B CZ 1 ATOM 8952 O OH . TYR B 1 422 ? -26.223 3.472 61.923 1.00 25.18 ? 442 TYR B OH 1 ATOM 8953 N N . ALA B 1 423 ? -23.715 3.100 66.900 1.00 23.24 ? 443 ALA B N 1 ATOM 8954 C CA . ALA B 1 423 ? -22.505 3.346 66.119 1.00 23.20 ? 443 ALA B CA 1 ATOM 8955 C C . ALA B 1 423 ? -22.763 2.924 64.677 1.00 22.90 ? 443 ALA B C 1 ATOM 8956 O O . ALA B 1 423 ? -23.294 1.847 64.432 1.00 22.64 ? 443 ALA B O 1 ATOM 8957 C CB . ALA B 1 423 ? -21.321 2.560 66.690 1.00 22.98 ? 443 ALA B CB 1 ATOM 8958 N N . GLY B 1 424 ? -22.396 3.770 63.724 1.00 22.96 ? 444 GLY B N 1 ATOM 8959 C CA . GLY B 1 424 ? -22.523 3.408 62.309 1.00 23.30 ? 444 GLY B CA 1 ATOM 8960 C C . GLY B 1 424 ? -21.465 4.049 61.421 1.00 23.24 ? 444 GLY B C 1 ATOM 8961 O O . GLY B 1 424 ? -20.979 5.143 61.710 1.00 23.31 ? 444 GLY B O 1 ATOM 8962 N N . LEU B 1 425 ? -21.109 3.350 60.344 1.00 22.75 ? 445 LEU B N 1 ATOM 8963 C CA . LEU B 1 425 ? -20.243 3.885 59.305 1.00 22.35 ? 445 LEU B CA 1 ATOM 8964 C C . LEU B 1 425 ? -20.947 3.748 57.945 1.00 21.98 ? 445 LEU B C 1 ATOM 8965 O O . LEU B 1 425 ? -21.166 2.641 57.450 1.00 21.72 ? 445 LEU B O 1 ATOM 8966 C CB . LEU B 1 425 ? -18.905 3.146 59.299 1.00 22.04 ? 445 LEU B CB 1 ATOM 8967 C CG . LEU B 1 425 ? -17.937 3.531 58.170 1.00 23.06 ? 445 LEU B CG 1 ATOM 8968 C CD1 . LEU B 1 425 ? -17.598 5.019 58.190 1.00 22.31 ? 445 LEU B CD1 1 ATOM 8969 C CD2 . LEU B 1 425 ? -16.663 2.705 58.252 1.00 23.38 ? 445 LEU B CD2 1 ATOM 8970 N N . LYS B 1 426 ? -21.309 4.884 57.364 1.00 21.90 ? 446 LYS B N 1 ATOM 8971 C CA . LYS B 1 426 ? -21.922 4.950 56.031 1.00 22.01 ? 446 LYS B CA 1 ATOM 8972 C C . LYS B 1 426 ? -21.102 4.139 55.034 1.00 21.74 ? 446 LYS B C 1 ATOM 8973 O O . LYS B 1 426 ? -19.872 4.181 55.060 1.00 21.54 ? 446 LYS B O 1 ATOM 8974 C CB . LYS B 1 426 ? -22.013 6.413 55.558 1.00 21.92 ? 446 LYS B CB 1 ATOM 8975 C CG . LYS B 1 426 ? -22.772 6.613 54.265 1.00 22.82 ? 446 LYS B CG 1 ATOM 8976 C CD . LYS B 1 426 ? -22.757 8.060 53.779 1.00 22.82 ? 446 LYS B CD 1 ATOM 8977 C CE . LYS B 1 426 ? -23.833 8.269 52.724 1.00 23.66 ? 446 LYS B CE 1 ATOM 8978 N NZ . LYS B 1 426 ? -23.591 9.394 51.785 1.00 24.71 ? 446 LYS B NZ 1 ATOM 8979 N N . GLY B 1 427 ? -21.790 3.383 54.179 1.00 21.36 ? 447 GLY B N 1 ATOM 8980 C CA . GLY B 1 427 ? -21.132 2.602 53.140 1.00 21.09 ? 447 GLY B CA 1 ATOM 8981 C C . GLY B 1 427 ? -20.724 3.451 51.947 1.00 20.97 ? 447 GLY B C 1 ATOM 8982 O O . GLY B 1 427 ? -21.543 4.203 51.411 1.00 20.71 ? 447 GLY B O 1 ATOM 8983 N N . GLN B 1 428 ? -19.448 3.351 51.562 1.00 20.78 ? 448 GLN B N 1 ATOM 8984 C CA . GLN B 1 428 ? -18.938 3.919 50.310 1.00 20.80 ? 448 GLN B CA 1 ATOM 8985 C C . GLN B 1 428 ? -18.019 2.903 49.676 1.00 20.63 ? 448 GLN B C 1 ATOM 8986 O O . GLN B 1 428 ? -17.440 2.072 50.375 1.00 20.79 ? 448 GLN B O 1 ATOM 8987 C CB . GLN B 1 428 ? -18.117 5.198 50.542 1.00 21.04 ? 448 GLN B CB 1 ATOM 8988 C CG . GLN B 1 428 ? -18.858 6.373 51.197 1.00 21.41 ? 448 GLN B CG 1 ATOM 8989 C CD . GLN B 1 428 ? -19.604 7.266 50.216 1.00 22.34 ? 448 GLN B CD 1 ATOM 8990 O OE1 . GLN B 1 428 ? -19.676 6.993 49.014 1.00 22.09 ? 448 GLN B OE1 1 ATOM 8991 N NE2 . GLN B 1 428 ? -20.175 8.346 50.735 1.00 22.89 ? 448 GLN B NE2 1 ATOM 8992 N N . VAL B 1 429 ? -17.882 2.973 48.353 1.00 20.41 ? 449 VAL B N 1 ATOM 8993 C CA A VAL B 1 429 ? -16.921 2.144 47.620 0.60 20.34 ? 449 VAL B CA 1 ATOM 8994 C CA B VAL B 1 429 ? -16.900 2.161 47.651 0.40 20.28 ? 449 VAL B CA 1 ATOM 8995 C C . VAL B 1 429 ? -16.270 2.969 46.524 1.00 20.18 ? 449 VAL B C 1 ATOM 8996 O O . VAL B 1 429 ? -16.890 3.874 45.991 1.00 20.06 ? 449 VAL B O 1 ATOM 8997 C CB A VAL B 1 429 ? -17.584 0.902 46.970 0.60 20.32 ? 449 VAL B CB 1 ATOM 8998 C CB B VAL B 1 429 ? -17.527 0.859 47.111 0.40 20.26 ? 449 VAL B CB 1 ATOM 8999 C CG1 A VAL B 1 429 ? -17.863 -0.172 48.017 0.60 20.71 ? 449 VAL B CG1 1 ATOM 9000 C CG1 B VAL B 1 429 ? -18.478 1.142 45.944 0.40 19.85 ? 449 VAL B CG1 1 ATOM 9001 C CG2 A VAL B 1 429 ? -18.861 1.285 46.221 0.60 19.68 ? 449 VAL B CG2 1 ATOM 9002 C CG2 B VAL B 1 429 ? -16.438 -0.119 46.716 0.40 20.19 ? 449 VAL B CG2 1 ATOM 9003 N N . LEU B 1 430 ? -15.018 2.654 46.201 1.00 19.95 ? 450 LEU B N 1 ATOM 9004 C CA . LEU B 1 430 ? -14.354 3.246 45.052 1.00 19.72 ? 450 LEU B CA 1 ATOM 9005 C C . LEU B 1 430 ? -14.511 2.273 43.887 1.00 19.27 ? 450 LEU B C 1 ATOM 9006 O O . LEU B 1 430 ? -14.197 1.102 44.028 1.00 19.86 ? 450 LEU B O 1 ATOM 9007 C CB . LEU B 1 430 ? -12.857 3.459 45.316 1.00 20.17 ? 450 LEU B CB 1 ATOM 9008 C CG . LEU B 1 430 ? -12.103 4.067 44.129 1.00 19.81 ? 450 LEU B CG 1 ATOM 9009 C CD1 . LEU B 1 430 ? -12.566 5.518 43.925 1.00 21.04 ? 450 LEU B CD1 1 ATOM 9010 C CD2 . LEU B 1 430 ? -10.591 3.985 44.319 1.00 21.40 ? 450 LEU B CD2 1 ATOM 9011 N N . VAL B 1 431 ? -14.955 2.768 42.739 1.00 18.63 ? 451 VAL B N 1 ATOM 9012 C CA . VAL B 1 431 ? -15.157 1.941 41.558 1.00 17.93 ? 451 VAL B CA 1 ATOM 9013 C C . VAL B 1 431 ? -14.252 2.454 40.430 1.00 18.24 ? 451 VAL B C 1 ATOM 9014 O O . VAL B 1 431 ? -14.246 3.651 40.123 1.00 17.77 ? 451 VAL B O 1 ATOM 9015 C CB . VAL B 1 431 ? -16.615 2.008 41.074 1.00 17.83 ? 451 VAL B CB 1 ATOM 9016 C CG1 . VAL B 1 431 ? -16.789 1.194 39.776 1.00 18.06 ? 451 VAL B CG1 1 ATOM 9017 C CG2 . VAL B 1 431 ? -17.574 1.532 42.177 1.00 16.38 ? 451 VAL B CG2 1 ATOM 9018 N N . LEU B 1 432 ? -13.481 1.531 39.852 1.00 18.22 ? 452 LEU B N 1 ATOM 9019 C CA . LEU B 1 432 ? -12.699 1.752 38.639 1.00 18.39 ? 452 LEU B CA 1 ATOM 9020 C C . LEU B 1 432 ? -13.369 0.922 37.551 1.00 17.84 ? 452 LEU B C 1 ATOM 9021 O O . LEU B 1 432 ? -13.478 -0.295 37.680 1.00 18.49 ? 452 LEU B O 1 ATOM 9022 C CB . LEU B 1 432 ? -11.245 1.269 38.813 1.00 18.27 ? 452 LEU B CB 1 ATOM 9023 C CG . LEU B 1 432 ? -10.423 1.305 37.516 1.00 18.79 ? 452 LEU B CG 1 ATOM 9024 C CD1 . LEU B 1 432 ? -10.394 2.720 36.965 1.00 19.44 ? 452 LEU B CD1 1 ATOM 9025 C CD2 . LEU B 1 432 ? -9.013 0.783 37.691 1.00 20.87 ? 452 LEU B CD2 1 ATOM 9026 N N . ARG B 1 433 ? -13.816 1.574 36.488 1.00 17.69 ? 453 ARG B N 1 ATOM 9027 C CA . ARG B 1 433 ? -14.654 0.906 35.496 1.00 17.43 ? 453 ARG B CA 1 ATOM 9028 C C . ARG B 1 433 ? -14.227 1.193 34.067 1.00 17.60 ? 453 ARG B C 1 ATOM 9029 O O . ARG B 1 433 ? -13.825 2.308 33.734 1.00 17.56 ? 453 ARG B O 1 ATOM 9030 C CB . ARG B 1 433 ? -16.105 1.339 35.684 1.00 17.20 ? 453 ARG B CB 1 ATOM 9031 C CG . ARG B 1 433 ? -17.044 0.995 34.521 1.00 17.02 ? 453 ARG B CG 1 ATOM 9032 C CD . ARG B 1 433 ? -18.467 1.357 34.881 1.00 17.94 ? 453 ARG B CD 1 ATOM 9033 N NE . ARG B 1 433 ? -18.920 0.566 36.024 1.00 18.94 ? 453 ARG B NE 1 ATOM 9034 C CZ . ARG B 1 433 ? -19.992 0.834 36.769 1.00 19.64 ? 453 ARG B CZ 1 ATOM 9035 N NH1 . ARG B 1 433 ? -20.759 1.894 36.521 1.00 18.94 ? 453 ARG B NH1 1 ATOM 9036 N NH2 . ARG B 1 433 ? -20.293 0.026 37.782 1.00 20.44 ? 453 ARG B NH2 1 ATOM 9037 N N . THR B 1 434 ? -14.317 0.175 33.227 1.00 17.88 ? 454 THR B N 1 ATOM 9038 C CA . THR B 1 434 ? -14.309 0.380 31.788 1.00 18.18 ? 454 THR B CA 1 ATOM 9039 C C . THR B 1 434 ? -15.382 -0.536 31.196 1.00 18.26 ? 454 THR B C 1 ATOM 9040 O O . THR B 1 434 ? -16.077 -1.240 31.928 1.00 18.76 ? 454 THR B O 1 ATOM 9041 C CB . THR B 1 434 ? -12.902 0.106 31.169 1.00 17.87 ? 454 THR B CB 1 ATOM 9042 O OG1 . THR B 1 434 ? -12.907 0.489 29.792 1.00 19.27 ? 454 THR B OG1 1 ATOM 9043 C CG2 . THR B 1 434 ? -12.527 -1.354 31.276 1.00 16.84 ? 454 THR B CG2 1 ATOM 9044 N N . THR B 1 435 ? -15.522 -0.526 29.880 1.00 18.60 ? 455 THR B N 1 ATOM 9045 C CA . THR B 1 435 ? -16.449 -1.427 29.200 1.00 19.04 ? 455 THR B CA 1 ATOM 9046 C C . THR B 1 435 ? -15.751 -2.053 28.006 1.00 19.72 ? 455 THR B C 1 ATOM 9047 O O . THR B 1 435 ? -14.641 -1.648 27.638 1.00 20.08 ? 455 THR B O 1 ATOM 9048 C CB . THR B 1 435 ? -17.690 -0.678 28.661 1.00 18.92 ? 455 THR B CB 1 ATOM 9049 O OG1 . THR B 1 435 ? -17.264 0.347 27.760 1.00 19.09 ? 455 THR B OG1 1 ATOM 9050 C CG2 . THR B 1 435 ? -18.528 -0.056 29.784 1.00 18.66 ? 455 THR B CG2 1 ATOM 9051 N N . SER B 1 436 ? -16.394 -3.044 27.404 1.00 20.56 ? 456 SER B N 1 ATOM 9052 C CA . SER B 1 436 ? -16.002 -3.498 26.066 1.00 21.03 ? 456 SER B CA 1 ATOM 9053 C C . SER B 1 436 ? -17.230 -3.866 25.258 1.00 21.12 ? 456 SER B C 1 ATOM 9054 O O . SER B 1 436 ? -18.036 -4.699 25.675 1.00 21.04 ? 456 SER B O 1 ATOM 9055 C CB . SER B 1 436 ? -15.033 -4.667 26.137 1.00 21.20 ? 456 SER B CB 1 ATOM 9056 O OG . SER B 1 436 ? -15.606 -5.740 26.824 1.00 23.73 ? 456 SER B OG 1 ATOM 9057 N N . THR B 1 437 ? -17.374 -3.203 24.115 1.00 21.50 ? 457 THR B N 1 ATOM 9058 C CA . THR B 1 437 ? -18.394 -3.513 23.142 1.00 21.69 ? 457 THR B CA 1 ATOM 9059 C C . THR B 1 437 ? -17.680 -3.916 21.853 1.00 22.87 ? 457 THR B C 1 ATOM 9060 O O . THR B 1 437 ? -17.270 -3.075 21.065 1.00 23.23 ? 457 THR B O 1 ATOM 9061 C CB . THR B 1 437 ? -19.292 -2.279 22.885 1.00 21.61 ? 457 THR B CB 1 ATOM 9062 O OG1 . THR B 1 437 ? -19.681 -1.685 24.134 1.00 20.69 ? 457 THR B OG1 1 ATOM 9063 C CG2 . THR B 1 437 ? -20.541 -2.662 22.064 1.00 20.24 ? 457 THR B CG2 1 ATOM 9064 N N . VAL B 1 438 ? -17.489 -5.203 21.634 1.00 24.19 ? 458 VAL B N 1 ATOM 9065 C CA . VAL B 1 438 ? -16.888 -5.622 20.372 1.00 25.07 ? 458 VAL B CA 1 ATOM 9066 C C . VAL B 1 438 ? -17.888 -5.346 19.244 1.00 25.40 ? 458 VAL B C 1 ATOM 9067 O O . VAL B 1 438 ? -17.514 -4.830 18.171 1.00 26.53 ? 458 VAL B O 1 ATOM 9068 C CB . VAL B 1 438 ? -16.500 -7.113 20.378 1.00 25.58 ? 458 VAL B CB 1 ATOM 9069 N N . TYR B 1 439 ? -19.156 -5.644 19.503 1.00 24.54 ? 459 TYR B N 1 ATOM 9070 C CA . TYR B 1 439 ? -20.168 -5.616 18.464 1.00 24.59 ? 459 TYR B CA 1 ATOM 9071 C C . TYR B 1 439 ? -21.566 -5.549 19.076 1.00 23.70 ? 459 TYR B C 1 ATOM 9072 O O . TYR B 1 439 ? -22.093 -4.456 19.273 1.00 24.13 ? 459 TYR B O 1 ATOM 9073 C CB . TYR B 1 439 ? -19.984 -6.863 17.593 1.00 25.04 ? 459 TYR B CB 1 ATOM 9074 C CG . TYR B 1 439 ? -20.788 -6.933 16.321 1.00 27.68 ? 459 TYR B CG 1 ATOM 9075 C CD1 . TYR B 1 439 ? -20.544 -6.052 15.274 1.00 30.45 ? 459 TYR B CD1 1 ATOM 9076 C CD2 . TYR B 1 439 ? -21.754 -7.924 16.135 1.00 29.38 ? 459 TYR B CD2 1 ATOM 9077 C CE1 . TYR B 1 439 ? -21.262 -6.137 14.077 1.00 31.28 ? 459 TYR B CE1 1 ATOM 9078 C CE2 . TYR B 1 439 ? -22.467 -8.023 14.948 1.00 29.86 ? 459 TYR B CE2 1 ATOM 9079 C CZ . TYR B 1 439 ? -22.217 -7.125 13.926 1.00 30.66 ? 459 TYR B CZ 1 ATOM 9080 O OH . TYR B 1 439 ? -22.907 -7.214 12.746 1.00 32.77 ? 459 TYR B OH 1 ATOM 9081 N N . ASN B 1 440 ? -22.139 -6.701 19.415 1.00 22.77 ? 460 ASN B N 1 ATOM 9082 C CA . ASN B 1 440 ? -23.525 -6.788 19.886 1.00 22.54 ? 460 ASN B CA 1 ATOM 9083 C C . ASN B 1 440 ? -23.672 -6.584 21.396 1.00 21.96 ? 460 ASN B C 1 ATOM 9084 O O . ASN B 1 440 ? -24.502 -5.786 21.839 1.00 21.50 ? 460 ASN B O 1 ATOM 9085 C CB . ASN B 1 440 ? -24.150 -8.128 19.467 1.00 22.70 ? 460 ASN B CB 1 ATOM 9086 C CG . ASN B 1 440 ? -23.375 -9.321 19.973 1.00 22.67 ? 460 ASN B CG 1 ATOM 9087 O OD1 . ASN B 1 440 ? -22.210 -9.484 19.643 1.00 21.95 ? 460 ASN B OD1 1 ATOM 9088 N ND2 . ASN B 1 440 ? -24.017 -10.159 20.790 1.00 23.14 ? 460 ASN B ND2 1 HETATM 9089 N N . TPQ B 1 441 ? -22.848 -7.292 22.167 1.00 21.56 ? 461 TPQ B N 1 HETATM 9090 C CA . TPQ B 1 441 ? -22.839 -7.214 23.626 1.00 21.90 ? 461 TPQ B CA 1 HETATM 9091 C CB . TPQ B 1 441 ? -22.212 -8.473 24.219 1.00 22.50 ? 461 TPQ B CB 1 HETATM 9092 C C . TPQ B 1 441 ? -21.940 -6.117 24.200 1.00 21.44 ? 461 TPQ B C 1 HETATM 9093 O O . TPQ B 1 441 ? -20.894 -5.790 23.631 1.00 20.90 ? 461 TPQ B O 1 HETATM 9094 C C1 . TPQ B 1 441 ? -23.192 -9.549 24.575 1.00 24.76 ? 461 TPQ B C1 1 HETATM 9095 C C2 . TPQ B 1 441 ? -23.009 -10.908 24.022 1.00 24.67 ? 461 TPQ B C2 1 HETATM 9096 O O2 . TPQ B 1 441 ? -22.067 -11.155 23.243 0.50 24.10 ? 461 TPQ B O2 1 HETATM 9097 C C3 . TPQ B 1 441 ? -23.985 -11.964 24.411 1.00 26.18 ? 461 TPQ B C3 1 HETATM 9098 C C4 . TPQ B 1 441 ? -25.055 -11.713 25.281 1.00 25.27 ? 461 TPQ B C4 1 HETATM 9099 O O4 . TPQ B 1 441 ? -25.848 -12.630 25.594 1.00 20.99 ? 461 TPQ B O4 1 HETATM 9100 C C5 . TPQ B 1 441 ? -25.226 -10.348 25.838 1.00 27.27 ? 461 TPQ B C5 1 HETATM 9101 O O5 . TPQ B 1 441 ? -26.168 -10.086 26.630 0.50 27.65 ? 461 TPQ B O5 1 HETATM 9102 C C6 . TPQ B 1 441 ? -24.242 -9.289 25.453 1.00 27.15 ? 461 TPQ B C6 1 ATOM 9103 N N . ASP B 1 442 ? -22.329 -5.603 25.366 1.00 20.98 ? 462 ASP B N 1 ATOM 9104 C CA . ASP B 1 442 ? -21.508 -4.665 26.125 1.00 20.09 ? 462 ASP B CA 1 ATOM 9105 C C . ASP B 1 442 ? -21.168 -5.280 27.483 1.00 19.79 ? 462 ASP B C 1 ATOM 9106 O O . ASP B 1 442 ? -22.081 -5.582 28.276 1.00 19.51 ? 462 ASP B O 1 ATOM 9107 C CB . ASP B 1 442 ? -22.263 -3.353 26.346 1.00 20.10 ? 462 ASP B CB 1 ATOM 9108 C CG . ASP B 1 442 ? -22.659 -2.688 25.059 1.00 20.59 ? 462 ASP B CG 1 ATOM 9109 O OD1 . ASP B 1 442 ? -23.407 -3.330 24.285 1.00 22.37 ? 462 ASP B OD1 1 ATOM 9110 O OD2 . ASP B 1 442 ? -22.236 -1.526 24.818 1.00 19.69 ? 462 ASP B OD2 1 ATOM 9111 N N . TYR B 1 443 ? -19.870 -5.473 27.750 1.00 19.01 ? 463 TYR B N 1 ATOM 9112 C CA A TYR B 1 443 ? -19.484 -5.893 29.075 0.50 18.50 ? 463 TYR B CA 1 ATOM 9113 C CA B TYR B 1 443 ? -19.347 -5.927 29.057 0.50 18.78 ? 463 TYR B CA 1 ATOM 9114 C C . TYR B 1 443 ? -19.010 -4.692 29.875 1.00 18.43 ? 463 TYR B C 1 ATOM 9115 O O . TYR B 1 443 ? -18.363 -3.781 29.354 1.00 18.25 ? 463 TYR B O 1 ATOM 9116 C CB A TYR B 1 443 ? -18.472 -7.025 29.004 0.50 18.54 ? 463 TYR B CB 1 ATOM 9117 C CB B TYR B 1 443 ? -17.998 -6.655 28.941 0.50 19.11 ? 463 TYR B CB 1 ATOM 9118 C CG A TYR B 1 443 ? -19.033 -8.198 28.233 0.50 18.23 ? 463 TYR B CG 1 ATOM 9119 C CG B TYR B 1 443 ? -17.932 -8.001 28.262 0.50 19.77 ? 463 TYR B CG 1 ATOM 9120 C CD1 A TYR B 1 443 ? -20.034 -8.990 28.769 0.50 18.16 ? 463 TYR B CD1 1 ATOM 9121 C CD1 B TYR B 1 443 ? -17.661 -8.104 26.908 0.50 21.17 ? 463 TYR B CD1 1 ATOM 9122 C CD2 A TYR B 1 443 ? -18.603 -8.476 26.949 0.50 19.47 ? 463 TYR B CD2 1 ATOM 9123 C CD2 B TYR B 1 443 ? -18.033 -9.170 28.995 0.50 20.59 ? 463 TYR B CD2 1 ATOM 9124 C CE1 A TYR B 1 443 ? -20.566 -10.043 28.060 0.50 18.20 ? 463 TYR B CE1 1 ATOM 9125 C CE1 B TYR B 1 443 ? -17.560 -9.340 26.296 0.50 21.45 ? 463 TYR B CE1 1 ATOM 9126 C CE2 A TYR B 1 443 ? -19.126 -9.532 26.236 0.50 19.15 ? 463 TYR B CE2 1 ATOM 9127 C CE2 B TYR B 1 443 ? -17.932 -10.404 28.396 0.50 20.61 ? 463 TYR B CE2 1 ATOM 9128 C CZ A TYR B 1 443 ? -20.107 -10.313 26.796 0.50 18.24 ? 463 TYR B CZ 1 ATOM 9129 C CZ B TYR B 1 443 ? -17.697 -10.485 27.051 0.50 20.83 ? 463 TYR B CZ 1 ATOM 9130 O OH A TYR B 1 443 ? -20.615 -11.370 26.076 0.50 18.27 ? 463 TYR B OH 1 ATOM 9131 O OH B TYR B 1 443 ? -17.602 -11.716 26.465 0.50 22.02 ? 463 TYR B OH 1 ATOM 9132 N N . ILE B 1 444 ? -19.380 -4.685 31.151 1.00 17.94 ? 464 ILE B N 1 ATOM 9133 C CA . ILE B 1 444 ? -19.013 -3.608 32.054 1.00 17.39 ? 464 ILE B CA 1 ATOM 9134 C C . ILE B 1 444 ? -18.050 -4.227 33.058 1.00 17.26 ? 464 ILE B C 1 ATOM 9135 O O . ILE B 1 444 ? -18.422 -5.147 33.786 1.00 17.50 ? 464 ILE B O 1 ATOM 9136 C CB . ILE B 1 444 ? -20.257 -2.998 32.732 1.00 16.79 ? 464 ILE B CB 1 ATOM 9137 C CG1 . ILE B 1 444 ? -21.182 -2.410 31.661 1.00 16.90 ? 464 ILE B CG1 1 ATOM 9138 C CG2 . ILE B 1 444 ? -19.862 -1.918 33.720 1.00 17.35 ? 464 ILE B CG2 1 ATOM 9139 C CD1 . ILE B 1 444 ? -22.560 -2.048 32.140 1.00 16.20 ? 464 ILE B CD1 1 ATOM 9140 N N . TRP B 1 445 ? -16.808 -3.741 33.066 1.00 17.33 ? 465 TRP B N 1 ATOM 9141 C CA . TRP B 1 445 ? -15.738 -4.287 33.922 1.00 16.99 ? 465 TRP B CA 1 ATOM 9142 C C . TRP B 1 445 ? -15.460 -3.360 35.100 1.00 17.42 ? 465 TRP B C 1 ATOM 9143 O O . TRP B 1 445 ? -15.078 -2.211 34.889 1.00 17.67 ? 465 TRP B O 1 ATOM 9144 C CB . TRP B 1 445 ? -14.451 -4.440 33.104 1.00 16.91 ? 465 TRP B CB 1 ATOM 9145 C CG . TRP B 1 445 ? -14.606 -5.284 31.917 1.00 15.35 ? 465 TRP B CG 1 ATOM 9146 C CD1 . TRP B 1 445 ? -14.758 -4.868 30.633 1.00 16.10 ? 465 TRP B CD1 1 ATOM 9147 C CD2 . TRP B 1 445 ? -14.627 -6.708 31.885 1.00 15.49 ? 465 TRP B CD2 1 ATOM 9148 N NE1 . TRP B 1 445 ? -14.873 -5.951 29.795 1.00 16.30 ? 465 TRP B NE1 1 ATOM 9149 C CE2 . TRP B 1 445 ? -14.788 -7.093 30.545 1.00 16.16 ? 465 TRP B CE2 1 ATOM 9150 C CE3 . TRP B 1 445 ? -14.527 -7.700 32.865 1.00 16.35 ? 465 TRP B CE3 1 ATOM 9151 C CZ2 . TRP B 1 445 ? -14.866 -8.427 30.161 1.00 17.73 ? 465 TRP B CZ2 1 ATOM 9152 C CZ3 . TRP B 1 445 ? -14.603 -9.015 32.485 1.00 16.48 ? 465 TRP B CZ3 1 ATOM 9153 C CH2 . TRP B 1 445 ? -14.770 -9.373 31.144 1.00 16.74 ? 465 TRP B CH2 1 ATOM 9154 N N . ASP B 1 446 ? -15.649 -3.859 36.326 1.00 17.85 ? 466 ASP B N 1 ATOM 9155 C CA . ASP B 1 446 ? -15.416 -3.093 37.564 1.00 18.25 ? 466 ASP B CA 1 ATOM 9156 C C . ASP B 1 446 ? -14.334 -3.708 38.448 1.00 18.23 ? 466 ASP B C 1 ATOM 9157 O O . ASP B 1 446 ? -14.219 -4.917 38.563 1.00 17.59 ? 466 ASP B O 1 ATOM 9158 C CB . ASP B 1 446 ? -16.681 -3.035 38.430 1.00 18.27 ? 466 ASP B CB 1 ATOM 9159 C CG . ASP B 1 446 ? -17.868 -2.376 37.733 1.00 19.62 ? 466 ASP B CG 1 ATOM 9160 O OD1 . ASP B 1 446 ? -17.701 -1.785 36.652 1.00 20.22 ? 466 ASP B OD1 1 ATOM 9161 O OD2 . ASP B 1 446 ? -18.982 -2.424 38.302 1.00 19.00 ? 466 ASP B OD2 1 ATOM 9162 N N . PHE B 1 447 ? -13.544 -2.841 39.071 1.00 19.06 ? 467 PHE B N 1 ATOM 9163 C CA . PHE B 1 447 ? -12.717 -3.200 40.211 1.00 19.11 ? 467 PHE B CA 1 ATOM 9164 C C . PHE B 1 447 ? -13.120 -2.233 41.314 1.00 19.23 ? 467 PHE B C 1 ATOM 9165 O O . PHE B 1 447 ? -13.127 -1.015 41.126 1.00 18.77 ? 467 PHE B O 1 ATOM 9166 C CB . PHE B 1 447 ? -11.235 -3.081 39.881 1.00 19.50 ? 467 PHE B CB 1 ATOM 9167 C CG . PHE B 1 447 ? -10.743 -4.146 38.954 1.00 20.04 ? 467 PHE B CG 1 ATOM 9168 C CD1 . PHE B 1 447 ? -10.329 -3.838 37.669 1.00 21.90 ? 467 PHE B CD1 1 ATOM 9169 C CD2 . PHE B 1 447 ? -10.706 -5.468 39.367 1.00 20.79 ? 467 PHE B CD2 1 ATOM 9170 C CE1 . PHE B 1 447 ? -9.872 -4.844 36.807 1.00 22.05 ? 467 PHE B CE1 1 ATOM 9171 C CE2 . PHE B 1 447 ? -10.265 -6.466 38.522 1.00 21.25 ? 467 PHE B CE2 1 ATOM 9172 C CZ . PHE B 1 447 ? -9.846 -6.157 37.241 1.00 21.83 ? 467 PHE B CZ 1 ATOM 9173 N N . ILE B 1 448 ? -13.480 -2.796 42.456 1.00 19.43 ? 468 ILE B N 1 ATOM 9174 C CA . ILE B 1 448 ? -14.223 -2.088 43.473 1.00 20.04 ? 468 ILE B CA 1 ATOM 9175 C C . ILE B 1 448 ? -13.439 -2.217 44.758 1.00 20.10 ? 468 ILE B C 1 ATOM 9176 O O . ILE B 1 448 ? -13.005 -3.323 45.094 1.00 20.20 ? 468 ILE B O 1 ATOM 9177 C CB . ILE B 1 448 ? -15.628 -2.733 43.629 1.00 20.19 ? 468 ILE B CB 1 ATOM 9178 C CG1 . ILE B 1 448 ? -16.427 -2.583 42.329 1.00 21.31 ? 468 ILE B CG1 1 ATOM 9179 C CG2 . ILE B 1 448 ? -16.395 -2.105 44.735 1.00 20.62 ? 468 ILE B CG2 1 ATOM 9180 C CD1 . ILE B 1 448 ? -17.598 -3.554 42.235 1.00 21.99 ? 468 ILE B CD1 1 ATOM 9181 N N . PHE B 1 449 ? -13.242 -1.095 45.453 1.00 20.01 ? 469 PHE B N 1 ATOM 9182 C CA . PHE B 1 449 ? -12.411 -1.056 46.642 1.00 20.53 ? 469 PHE B CA 1 ATOM 9183 C C . PHE B 1 449 ? -13.202 -0.499 47.823 1.00 20.68 ? 469 PHE B C 1 ATOM 9184 O O . PHE B 1 449 ? -13.651 0.649 47.798 1.00 20.56 ? 469 PHE B O 1 ATOM 9185 C CB . PHE B 1 449 ? -11.154 -0.208 46.400 1.00 20.95 ? 469 PHE B CB 1 ATOM 9186 C CG . PHE B 1 449 ? -10.356 -0.632 45.193 1.00 20.60 ? 469 PHE B CG 1 ATOM 9187 C CD1 . PHE B 1 449 ? -10.716 -0.210 43.925 1.00 21.17 ? 469 PHE B CD1 1 ATOM 9188 C CD2 . PHE B 1 449 ? -9.244 -1.457 45.331 1.00 21.62 ? 469 PHE B CD2 1 ATOM 9189 C CE1 . PHE B 1 449 ? -9.982 -0.602 42.794 1.00 22.36 ? 469 PHE B CE1 1 ATOM 9190 C CE2 . PHE B 1 449 ? -8.491 -1.851 44.207 1.00 20.97 ? 469 PHE B CE2 1 ATOM 9191 C CZ . PHE B 1 449 ? -8.867 -1.433 42.941 1.00 21.41 ? 469 PHE B CZ 1 ATOM 9192 N N . TYR B 1 450 ? -13.378 -1.330 48.849 1.00 20.76 ? 470 TYR B N 1 ATOM 9193 C CA . TYR B 1 450 ? -14.137 -0.946 50.036 1.00 20.84 ? 470 TYR B CA 1 ATOM 9194 C C . TYR B 1 450 ? -13.159 -0.377 51.051 1.00 20.98 ? 470 TYR B C 1 ATOM 9195 O O . TYR B 1 450 ? -11.984 -0.768 51.047 1.00 20.97 ? 470 TYR B O 1 ATOM 9196 C CB . TYR B 1 450 ? -14.844 -2.150 50.649 1.00 20.84 ? 470 TYR B CB 1 ATOM 9197 C CG . TYR B 1 450 ? -15.933 -2.772 49.805 1.00 21.83 ? 470 TYR B CG 1 ATOM 9198 C CD1 . TYR B 1 450 ? -15.626 -3.542 48.693 1.00 23.44 ? 470 TYR B CD1 1 ATOM 9199 C CD2 . TYR B 1 450 ? -17.272 -2.615 50.144 1.00 23.09 ? 470 TYR B CD2 1 ATOM 9200 C CE1 . TYR B 1 450 ? -16.631 -4.118 47.915 1.00 25.01 ? 470 TYR B CE1 1 ATOM 9201 C CE2 . TYR B 1 450 ? -18.279 -3.197 49.393 1.00 24.26 ? 470 TYR B CE2 1 ATOM 9202 C CZ . TYR B 1 450 ? -17.950 -3.951 48.279 1.00 24.97 ? 470 TYR B CZ 1 ATOM 9203 O OH . TYR B 1 450 ? -18.938 -4.520 47.522 1.00 26.59 ? 470 TYR B OH 1 ATOM 9204 N N . PRO B 1 451 ? -13.635 0.515 51.949 1.00 21.03 ? 471 PRO B N 1 ATOM 9205 C CA . PRO B 1 451 ? -12.759 1.137 52.953 1.00 21.01 ? 471 PRO B CA 1 ATOM 9206 C C . PRO B 1 451 ? -12.136 0.192 53.984 1.00 20.99 ? 471 PRO B C 1 ATOM 9207 O O . PRO B 1 451 ? -11.206 0.604 54.685 1.00 20.97 ? 471 PRO B O 1 ATOM 9208 C CB . PRO B 1 451 ? -13.680 2.142 53.658 1.00 20.86 ? 471 PRO B CB 1 ATOM 9209 C CG . PRO B 1 451 ? -14.742 2.436 52.681 1.00 21.20 ? 471 PRO B CG 1 ATOM 9210 C CD . PRO B 1 451 ? -14.970 1.142 51.941 1.00 21.04 ? 471 PRO B CD 1 ATOM 9211 N N . ASN B 1 452 ? -12.649 -1.037 54.088 1.00 21.00 ? 472 ASN B N 1 ATOM 9212 C CA . ASN B 1 452 ? -12.120 -2.033 55.030 1.00 21.00 ? 472 ASN B CA 1 ATOM 9213 C C . ASN B 1 452 ? -11.174 -3.053 54.389 1.00 20.84 ? 472 ASN B C 1 ATOM 9214 O O . ASN B 1 452 ? -11.029 -4.165 54.881 1.00 21.08 ? 472 ASN B O 1 ATOM 9215 C CB . ASN B 1 452 ? -13.273 -2.769 55.721 1.00 20.77 ? 472 ASN B CB 1 ATOM 9216 C CG . ASN B 1 452 ? -14.080 -3.604 54.763 1.00 21.13 ? 472 ASN B CG 1 ATOM 9217 O OD1 . ASN B 1 452 ? -14.008 -3.416 53.538 1.00 19.21 ? 472 ASN B OD1 1 ATOM 9218 N ND2 . ASN B 1 452 ? -14.866 -4.531 55.307 1.00 20.37 ? 472 ASN B ND2 1 ATOM 9219 N N . GLY B 1 453 ? -10.548 -2.682 53.276 1.00 21.29 ? 473 GLY B N 1 ATOM 9220 C CA . GLY B 1 453 ? -9.535 -3.528 52.638 1.00 20.99 ? 473 GLY B CA 1 ATOM 9221 C C . GLY B 1 453 ? -10.067 -4.640 51.762 1.00 20.96 ? 473 GLY B C 1 ATOM 9222 O O . GLY B 1 453 ? -9.294 -5.452 51.262 1.00 20.88 ? 473 GLY B O 1 ATOM 9223 N N . VAL B 1 454 ? -11.383 -4.700 51.588 1.00 21.00 ? 474 VAL B N 1 ATOM 9224 C CA . VAL B 1 454 ? -11.986 -5.692 50.706 1.00 21.24 ? 474 VAL B CA 1 ATOM 9225 C C . VAL B 1 454 ? -12.020 -5.122 49.290 1.00 21.44 ? 474 VAL B C 1 ATOM 9226 O O . VAL B 1 454 ? -12.492 -4.010 49.095 1.00 21.68 ? 474 VAL B O 1 ATOM 9227 C CB . VAL B 1 454 ? -13.415 -6.059 51.164 1.00 21.54 ? 474 VAL B CB 1 ATOM 9228 C CG1 . VAL B 1 454 ? -14.114 -6.998 50.133 1.00 20.95 ? 474 VAL B CG1 1 ATOM 9229 C CG2 . VAL B 1 454 ? -13.371 -6.697 52.553 1.00 20.90 ? 474 VAL B CG2 1 ATOM 9230 N N . MET B 1 455 ? -11.500 -5.861 48.315 1.00 21.82 ? 475 MET B N 1 ATOM 9231 C CA . MET B 1 455 ? -11.659 -5.468 46.911 1.00 22.69 ? 475 MET B CA 1 ATOM 9232 C C . MET B 1 455 ? -12.426 -6.523 46.138 1.00 22.35 ? 475 MET B C 1 ATOM 9233 O O . MET B 1 455 ? -12.415 -7.694 46.475 1.00 22.84 ? 475 MET B O 1 ATOM 9234 C CB . MET B 1 455 ? -10.323 -5.122 46.224 1.00 22.92 ? 475 MET B CB 1 ATOM 9235 C CG . MET B 1 455 ? -9.504 -6.267 45.666 1.00 25.65 ? 475 MET B CG 1 ATOM 9236 S SD . MET B 1 455 ? -8.336 -5.731 44.341 1.00 30.06 ? 475 MET B SD 1 ATOM 9237 C CE . MET B 1 455 ? -9.359 -5.722 42.885 1.00 29.80 ? 475 MET B CE 1 ATOM 9238 N N . GLU B 1 456 ? -13.095 -6.086 45.090 1.00 22.45 ? 476 GLU B N 1 ATOM 9239 C CA . GLU B 1 456 ? -13.996 -6.951 44.350 1.00 22.24 ? 476 GLU B CA 1 ATOM 9240 C C . GLU B 1 456 ? -13.795 -6.743 42.851 1.00 21.82 ? 476 GLU B C 1 ATOM 9241 O O . GLU B 1 456 ? -13.602 -5.618 42.394 1.00 21.54 ? 476 GLU B O 1 ATOM 9242 C CB . GLU B 1 456 ? -15.436 -6.637 44.766 1.00 22.21 ? 476 GLU B CB 1 ATOM 9243 C CG . GLU B 1 456 ? -16.509 -7.428 44.042 1.00 22.94 ? 476 GLU B CG 1 ATOM 9244 C CD . GLU B 1 456 ? -17.914 -7.099 44.537 1.00 23.89 ? 476 GLU B CD 1 ATOM 9245 O OE1 . GLU B 1 456 ? -18.070 -6.151 45.329 1.00 24.18 ? 476 GLU B OE1 1 ATOM 9246 O OE2 . GLU B 1 456 ? -18.868 -7.780 44.110 1.00 24.49 ? 476 GLU B OE2 1 ATOM 9247 N N . ALA B 1 457 ? -13.818 -7.837 42.096 1.00 21.35 ? 477 ALA B N 1 ATOM 9248 C CA . ALA B 1 457 ? -13.873 -7.759 40.646 1.00 21.26 ? 477 ALA B CA 1 ATOM 9249 C C . ALA B 1 457 ? -15.295 -8.096 40.212 1.00 21.43 ? 477 ALA B C 1 ATOM 9250 O O . ALA B 1 457 ? -15.950 -8.939 40.816 1.00 21.18 ? 477 ALA B O 1 ATOM 9251 C CB . ALA B 1 457 ? -12.884 -8.719 40.022 1.00 20.91 ? 477 ALA B CB 1 ATOM 9252 N N . LYS B 1 458 ? -15.771 -7.426 39.172 1.00 21.87 ? 478 LYS B N 1 ATOM 9253 C CA . LYS B 1 458 ? -17.110 -7.679 38.669 1.00 22.29 ? 478 LYS B CA 1 ATOM 9254 C C . LYS B 1 458 ? -17.193 -7.467 37.159 1.00 21.99 ? 478 LYS B C 1 ATOM 9255 O O . LYS B 1 458 ? -16.587 -6.537 36.618 1.00 21.50 ? 478 LYS B O 1 ATOM 9256 C CB . LYS B 1 458 ? -18.100 -6.764 39.390 1.00 22.75 ? 478 LYS B CB 1 ATOM 9257 C CG . LYS B 1 458 ? -19.514 -7.250 39.396 1.00 24.70 ? 478 LYS B CG 1 ATOM 9258 C CD . LYS B 1 458 ? -20.442 -6.264 40.103 1.00 26.58 ? 478 LYS B CD 1 ATOM 9259 C CE . LYS B 1 458 ? -20.199 -6.175 41.580 1.00 28.45 ? 478 LYS B CE 1 ATOM 9260 N NZ . LYS B 1 458 ? -21.301 -5.402 42.264 1.00 29.90 ? 478 LYS B NZ 1 ATOM 9261 N N . MET B 1 459 ? -17.930 -8.355 36.489 1.00 21.80 ? 479 MET B N 1 ATOM 9262 C CA . MET B 1 459 ? -18.329 -8.163 35.102 1.00 21.45 ? 479 MET B CA 1 ATOM 9263 C C . MET B 1 459 ? -19.859 -8.150 35.051 1.00 21.00 ? 479 MET B C 1 ATOM 9264 O O . MET B 1 459 ? -20.491 -9.003 35.665 1.00 20.57 ? 479 MET B O 1 ATOM 9265 C CB . MET B 1 459 ? -17.767 -9.289 34.237 1.00 21.99 ? 479 MET B CB 1 ATOM 9266 C CG . MET B 1 459 ? -18.095 -9.185 32.752 1.00 23.34 ? 479 MET B CG 1 ATOM 9267 S SD . MET B 1 459 ? -19.708 -9.895 32.343 1.00 29.10 ? 479 MET B SD 1 ATOM 9268 C CE . MET B 1 459 ? -19.371 -11.653 32.336 1.00 27.46 ? 479 MET B CE 1 ATOM 9269 N N . HIS B 1 460 ? -20.442 -7.180 34.336 1.00 20.21 ? 480 HIS B N 1 ATOM 9270 C CA . HIS B 1 460 ? -21.884 -7.172 34.031 1.00 19.89 ? 480 HIS B CA 1 ATOM 9271 C C . HIS B 1 460 ? -22.086 -7.293 32.531 1.00 19.40 ? 480 HIS B C 1 ATOM 9272 O O . HIS B 1 460 ? -21.380 -6.655 31.773 1.00 19.99 ? 480 HIS B O 1 ATOM 9273 C CB . HIS B 1 460 ? -22.570 -5.861 34.460 1.00 19.67 ? 480 HIS B CB 1 ATOM 9274 C CG . HIS B 1 460 ? -22.093 -5.304 35.761 1.00 19.65 ? 480 HIS B CG 1 ATOM 9275 N ND1 . HIS B 1 460 ? -22.843 -5.375 36.914 1.00 18.88 ? 480 HIS B ND1 1 ATOM 9276 C CD2 . HIS B 1 460 ? -20.962 -4.631 36.086 1.00 19.21 ? 480 HIS B CD2 1 ATOM 9277 C CE1 . HIS B 1 460 ? -22.189 -4.779 37.896 1.00 20.11 ? 480 HIS B CE1 1 ATOM 9278 N NE2 . HIS B 1 460 ? -21.043 -4.325 37.422 1.00 19.51 ? 480 HIS B NE2 1 ATOM 9279 N N . ALA B 1 461 ? -23.077 -8.067 32.108 1.00 18.97 ? 481 ALA B N 1 ATOM 9280 C CA . ALA B 1 461 ? -23.405 -8.201 30.701 1.00 18.70 ? 481 ALA B CA 1 ATOM 9281 C C . ALA B 1 461 ? -24.670 -7.409 30.382 1.00 18.72 ? 481 ALA B C 1 ATOM 9282 O O . ALA B 1 461 ? -25.676 -7.490 31.100 1.00 18.30 ? 481 ALA B O 1 ATOM 9283 C CB . ALA B 1 461 ? -23.604 -9.659 30.340 1.00 18.56 ? 481 ALA B CB 1 ATOM 9284 N N . THR B 1 462 ? -24.599 -6.630 29.306 1.00 18.61 ? 482 THR B N 1 ATOM 9285 C CA . THR B 1 462 ? -25.772 -5.975 28.740 1.00 18.36 ? 482 THR B CA 1 ATOM 9286 C C . THR B 1 462 ? -25.588 -5.874 27.213 1.00 18.80 ? 482 THR B C 1 ATOM 9287 O O . THR B 1 462 ? -24.786 -6.617 26.636 1.00 19.17 ? 482 THR B O 1 ATOM 9288 C CB . THR B 1 462 ? -26.059 -4.621 29.437 1.00 18.38 ? 482 THR B CB 1 ATOM 9289 O OG1 . THR B 1 462 ? -27.247 -4.035 28.890 1.00 17.96 ? 482 THR B OG1 1 ATOM 9290 C CG2 . THR B 1 462 ? -24.874 -3.647 29.309 1.00 17.20 ? 482 THR B CG2 1 ATOM 9291 N N . GLY B 1 463 ? -26.316 -4.986 26.551 1.00 18.55 ? 483 GLY B N 1 ATOM 9292 C CA . GLY B 1 463 ? -26.284 -4.925 25.086 1.00 18.45 ? 483 GLY B CA 1 ATOM 9293 C C . GLY B 1 463 ? -27.141 -5.994 24.423 1.00 18.25 ? 483 GLY B C 1 ATOM 9294 O O . GLY B 1 463 ? -28.054 -6.536 25.049 1.00 17.79 ? 483 GLY B O 1 ATOM 9295 N N . TYR B 1 464 ? -26.836 -6.307 23.162 1.00 18.09 ? 484 TYR B N 1 ATOM 9296 C CA . TYR B 1 464 ? -27.668 -7.214 22.359 1.00 18.29 ? 484 TYR B CA 1 ATOM 9297 C C . TYR B 1 464 ? -27.140 -8.640 22.376 1.00 18.36 ? 484 TYR B C 1 ATOM 9298 O O . TYR B 1 464 ? -25.924 -8.865 22.261 1.00 18.59 ? 484 TYR B O 1 ATOM 9299 C CB . TYR B 1 464 ? -27.721 -6.755 20.903 1.00 18.39 ? 484 TYR B CB 1 ATOM 9300 C CG . TYR B 1 464 ? -28.491 -5.468 20.653 1.00 18.70 ? 484 TYR B CG 1 ATOM 9301 C CD1 . TYR B 1 464 ? -27.862 -4.233 20.724 1.00 18.58 ? 484 TYR B CD1 1 ATOM 9302 C CD2 . TYR B 1 464 ? -29.843 -5.497 20.317 1.00 17.44 ? 484 TYR B CD2 1 ATOM 9303 C CE1 . TYR B 1 464 ? -28.561 -3.059 20.486 1.00 18.42 ? 484 TYR B CE1 1 ATOM 9304 C CE2 . TYR B 1 464 ? -30.550 -4.335 20.081 1.00 17.06 ? 484 TYR B CE2 1 ATOM 9305 C CZ . TYR B 1 464 ? -29.904 -3.120 20.155 1.00 18.33 ? 484 TYR B CZ 1 ATOM 9306 O OH . TYR B 1 464 ? -30.596 -1.966 19.913 1.00 17.46 ? 484 TYR B OH 1 ATOM 9307 N N . VAL B 1 465 ? -28.059 -9.598 22.477 1.00 18.10 ? 485 VAL B N 1 ATOM 9308 C CA . VAL B 1 465 ? -27.708 -11.015 22.398 1.00 18.09 ? 485 VAL B CA 1 ATOM 9309 C C . VAL B 1 465 ? -27.284 -11.439 20.991 1.00 18.59 ? 485 VAL B C 1 ATOM 9310 O O . VAL B 1 465 ? -27.653 -10.809 19.992 1.00 17.91 ? 485 VAL B O 1 ATOM 9311 C CB . VAL B 1 465 ? -28.890 -11.943 22.820 1.00 18.33 ? 485 VAL B CB 1 ATOM 9312 C CG1 . VAL B 1 465 ? -29.221 -11.755 24.297 1.00 17.11 ? 485 VAL B CG1 1 ATOM 9313 C CG2 . VAL B 1 465 ? -30.126 -11.735 21.913 1.00 17.61 ? 485 VAL B CG2 1 ATOM 9314 N N . HIS B 1 466 ? -26.508 -12.521 20.937 1.00 18.94 ? 486 HIS B N 1 ATOM 9315 C CA . HIS B 1 466 ? -26.148 -13.181 19.686 1.00 19.40 ? 486 HIS B CA 1 ATOM 9316 C C . HIS B 1 466 ? -27.319 -14.081 19.297 1.00 19.62 ? 486 HIS B C 1 ATOM 9317 O O . HIS B 1 466 ? -27.683 -14.985 20.040 1.00 20.36 ? 486 HIS B O 1 ATOM 9318 C CB . HIS B 1 466 ? -24.872 -13.991 19.887 1.00 19.17 ? 486 HIS B CB 1 ATOM 9319 C CG . HIS B 1 466 ? -24.337 -14.621 18.640 1.00 19.24 ? 486 HIS B CG 1 ATOM 9320 N ND1 . HIS B 1 466 ? -24.068 -13.899 17.498 1.00 18.80 ? 486 HIS B ND1 1 ATOM 9321 C CD2 . HIS B 1 466 ? -23.976 -15.902 18.374 1.00 18.63 ? 486 HIS B CD2 1 ATOM 9322 C CE1 . HIS B 1 466 ? -23.579 -14.710 16.575 1.00 19.41 ? 486 HIS B CE1 1 ATOM 9323 N NE2 . HIS B 1 466 ? -23.512 -15.931 17.082 1.00 19.16 ? 486 HIS B NE2 1 ATOM 9324 N N . ALA B 1 467 ? -27.912 -13.813 18.140 1.00 20.00 ? 487 ALA B N 1 ATOM 9325 C CA . ALA B 1 467 ? -29.200 -14.400 17.769 1.00 20.11 ? 487 ALA B CA 1 ATOM 9326 C C . ALA B 1 467 ? -29.224 -14.864 16.314 1.00 20.32 ? 487 ALA B C 1 ATOM 9327 O O . ALA B 1 467 ? -28.476 -14.361 15.475 1.00 20.88 ? 487 ALA B O 1 ATOM 9328 C CB . ALA B 1 467 ? -30.334 -13.385 18.025 1.00 19.47 ? 487 ALA B CB 1 ATOM 9329 N N . THR B 1 468 ? -30.104 -15.817 16.024 1.00 20.54 ? 488 THR B N 1 ATOM 9330 C CA . THR B 1 468 ? -30.221 -16.400 14.689 1.00 20.43 ? 488 THR B CA 1 ATOM 9331 C C . THR B 1 468 ? -31.697 -16.525 14.276 1.00 20.76 ? 488 THR B C 1 ATOM 9332 O O . THR B 1 468 ? -32.606 -16.223 15.067 1.00 20.01 ? 488 THR B O 1 ATOM 9333 C CB . THR B 1 468 ? -29.548 -17.787 14.656 1.00 20.61 ? 488 THR B CB 1 ATOM 9334 O OG1 . THR B 1 468 ? -30.071 -18.594 15.724 1.00 19.02 ? 488 THR B OG1 1 ATOM 9335 C CG2 . THR B 1 468 ? -28.031 -17.655 14.809 1.00 20.13 ? 488 THR B CG2 1 ATOM 9336 N N . PHE B 1 469 ? -31.921 -16.978 13.045 1.00 20.97 ? 489 PHE B N 1 ATOM 9337 C CA . PHE B 1 469 ? -33.257 -17.010 12.446 1.00 21.46 ? 489 PHE B CA 1 ATOM 9338 C C . PHE B 1 469 ? -34.116 -18.106 13.051 1.00 21.52 ? 489 PHE B C 1 ATOM 9339 O O . PHE B 1 469 ? -33.661 -19.235 13.204 1.00 21.31 ? 489 PHE B O 1 ATOM 9340 C CB . PHE B 1 469 ? -33.137 -17.236 10.940 1.00 21.70 ? 489 PHE B CB 1 ATOM 9341 C CG . PHE B 1 469 ? -34.443 -17.149 10.196 1.00 22.76 ? 489 PHE B CG 1 ATOM 9342 C CD1 . PHE B 1 469 ? -35.057 -15.928 9.986 1.00 22.90 ? 489 PHE B CD1 1 ATOM 9343 C CD2 . PHE B 1 469 ? -35.032 -18.287 9.668 1.00 24.32 ? 489 PHE B CD2 1 ATOM 9344 C CE1 . PHE B 1 469 ? -36.247 -15.843 9.279 1.00 23.89 ? 489 PHE B CE1 1 ATOM 9345 C CE2 . PHE B 1 469 ? -36.233 -18.208 8.965 1.00 24.39 ? 489 PHE B CE2 1 ATOM 9346 C CZ . PHE B 1 469 ? -36.839 -16.993 8.776 1.00 23.37 ? 489 PHE B CZ 1 ATOM 9347 N N . TYR B 1 470 ? -35.363 -17.772 13.380 1.00 22.11 ? 490 TYR B N 1 ATOM 9348 C CA . TYR B 1 470 ? -36.296 -18.740 13.947 1.00 22.52 ? 490 TYR B CA 1 ATOM 9349 C C . TYR B 1 470 ? -36.707 -19.843 12.969 1.00 23.08 ? 490 TYR B C 1 ATOM 9350 O O . TYR B 1 470 ? -37.178 -19.558 11.869 1.00 23.17 ? 490 TYR B O 1 ATOM 9351 C CB . TYR B 1 470 ? -37.585 -18.068 14.445 1.00 22.66 ? 490 TYR B CB 1 ATOM 9352 C CG . TYR B 1 470 ? -38.615 -19.107 14.837 1.00 22.41 ? 490 TYR B CG 1 ATOM 9353 C CD1 . TYR B 1 470 ? -39.664 -19.435 13.988 1.00 23.15 ? 490 TYR B CD1 1 ATOM 9354 C CD2 . TYR B 1 470 ? -38.478 -19.824 16.021 1.00 22.38 ? 490 TYR B CD2 1 ATOM 9355 C CE1 . TYR B 1 470 ? -40.582 -20.427 14.331 1.00 23.59 ? 490 TYR B CE1 1 ATOM 9356 C CE2 . TYR B 1 470 ? -39.381 -20.806 16.375 1.00 23.30 ? 490 TYR B CE2 1 ATOM 9357 C CZ . TYR B 1 470 ? -40.438 -21.097 15.526 1.00 24.06 ? 490 TYR B CZ 1 ATOM 9358 O OH . TYR B 1 470 ? -41.330 -22.070 15.879 1.00 25.72 ? 490 TYR B OH 1 ATOM 9359 N N . THR B 1 471 ? -36.515 -21.092 13.390 1.00 23.52 ? 491 THR B N 1 ATOM 9360 C CA . THR B 1 471 ? -37.279 -22.241 12.878 1.00 24.48 ? 491 THR B CA 1 ATOM 9361 C C . THR B 1 471 ? -37.665 -23.085 14.095 1.00 25.02 ? 491 THR B C 1 ATOM 9362 O O . THR B 1 471 ? -37.021 -22.967 15.131 1.00 24.98 ? 491 THR B O 1 ATOM 9363 C CB . THR B 1 471 ? -36.475 -23.144 11.900 1.00 24.32 ? 491 THR B CB 1 ATOM 9364 O OG1 . THR B 1 471 ? -35.501 -23.900 12.632 1.00 23.70 ? 491 THR B OG1 1 ATOM 9365 C CG2 . THR B 1 471 ? -35.794 -22.332 10.805 1.00 23.74 ? 491 THR B CG2 1 ATOM 9366 N N . PRO B 1 472 ? -38.693 -23.953 13.975 1.00 25.94 ? 492 PRO B N 1 ATOM 9367 C CA . PRO B 1 472 ? -39.055 -24.839 15.097 1.00 26.33 ? 492 PRO B CA 1 ATOM 9368 C C . PRO B 1 472 ? -37.865 -25.604 15.695 1.00 26.77 ? 492 PRO B C 1 ATOM 9369 O O . PRO B 1 472 ? -37.774 -25.751 16.916 1.00 26.57 ? 492 PRO B O 1 ATOM 9370 C CB . PRO B 1 472 ? -40.063 -25.803 14.467 1.00 26.37 ? 492 PRO B CB 1 ATOM 9371 C CG . PRO B 1 472 ? -40.732 -24.967 13.397 1.00 26.54 ? 492 PRO B CG 1 ATOM 9372 C CD . PRO B 1 472 ? -39.611 -24.116 12.832 1.00 26.12 ? 492 PRO B CD 1 ATOM 9373 N N . GLU B 1 473 ? -36.948 -26.045 14.835 1.00 27.35 ? 493 GLU B N 1 ATOM 9374 C CA . GLU B 1 473 ? -35.791 -26.835 15.255 1.00 28.03 ? 493 GLU B CA 1 ATOM 9375 C C . GLU B 1 473 ? -34.883 -26.082 16.211 1.00 27.53 ? 493 GLU B C 1 ATOM 9376 O O . GLU B 1 473 ? -34.183 -26.687 17.032 1.00 28.39 ? 493 GLU B O 1 ATOM 9377 C CB . GLU B 1 473 ? -34.973 -27.269 14.042 1.00 28.83 ? 493 GLU B CB 1 ATOM 9378 C CG . GLU B 1 473 ? -35.529 -28.473 13.294 1.00 31.57 ? 493 GLU B CG 1 ATOM 9379 C CD . GLU B 1 473 ? -36.748 -28.170 12.425 1.00 35.36 ? 493 GLU B CD 1 ATOM 9380 O OE1 . GLU B 1 473 ? -37.154 -26.994 12.277 1.00 34.97 ? 493 GLU B OE1 1 ATOM 9381 O OE2 . GLU B 1 473 ? -37.303 -29.145 11.874 1.00 39.58 ? 493 GLU B OE2 1 ATOM 9382 N N . GLY B 1 474 ? -34.885 -24.760 16.099 1.00 26.78 ? 494 GLY B N 1 ATOM 9383 C CA . GLY B 1 474 ? -34.095 -23.914 16.976 1.00 26.19 ? 494 GLY B CA 1 ATOM 9384 C C . GLY B 1 474 ? -34.465 -23.974 18.440 1.00 25.33 ? 494 GLY B C 1 ATOM 9385 O O . GLY B 1 474 ? -33.631 -23.675 19.295 1.00 25.36 ? 494 GLY B O 1 ATOM 9386 N N . LEU B 1 475 ? -35.699 -24.365 18.742 1.00 24.13 ? 495 LEU B N 1 ATOM 9387 C CA . LEU B 1 475 ? -36.163 -24.397 20.130 1.00 23.63 ? 495 LEU B CA 1 ATOM 9388 C C . LEU B 1 475 ? -35.390 -25.421 20.992 1.00 23.06 ? 495 LEU B C 1 ATOM 9389 O O . LEU B 1 475 ? -35.442 -25.377 22.221 1.00 22.47 ? 495 LEU B O 1 ATOM 9390 C CB . LEU B 1 475 ? -37.680 -24.645 20.177 1.00 23.39 ? 495 LEU B CB 1 ATOM 9391 C CG . LEU B 1 475 ? -38.538 -23.550 19.521 1.00 24.16 ? 495 LEU B CG 1 ATOM 9392 C CD1 . LEU B 1 475 ? -40.055 -23.850 19.627 1.00 23.81 ? 495 LEU B CD1 1 ATOM 9393 C CD2 . LEU B 1 475 ? -38.222 -22.184 20.139 1.00 24.15 ? 495 LEU B CD2 1 ATOM 9394 N N . ARG B 1 476 ? -34.677 -26.335 20.340 1.00 23.01 ? 496 ARG B N 1 ATOM 9395 C CA . ARG B 1 476 ? -33.742 -27.231 21.017 1.00 23.02 ? 496 ARG B CA 1 ATOM 9396 C C . ARG B 1 476 ? -32.410 -26.554 21.417 1.00 22.36 ? 496 ARG B C 1 ATOM 9397 O O . ARG B 1 476 ? -31.648 -27.129 22.195 1.00 21.89 ? 496 ARG B O 1 ATOM 9398 C CB . ARG B 1 476 ? -33.449 -28.458 20.145 1.00 23.48 ? 496 ARG B CB 1 ATOM 9399 C CG . ARG B 1 476 ? -34.620 -29.435 20.031 1.00 26.28 ? 496 ARG B CG 1 ATOM 9400 C CD . ARG B 1 476 ? -34.237 -30.702 19.247 1.00 28.57 ? 496 ARG B CD 1 ATOM 9401 N NE . ARG B 1 476 ? -33.113 -31.391 19.893 1.00 29.72 ? 496 ARG B NE 1 ATOM 9402 C CZ . ARG B 1 476 ? -31.857 -31.437 19.443 1.00 30.39 ? 496 ARG B CZ 1 ATOM 9403 N NH1 . ARG B 1 476 ? -31.505 -30.859 18.301 1.00 31.69 ? 496 ARG B NH1 1 ATOM 9404 N NH2 . ARG B 1 476 ? -30.939 -32.087 20.143 1.00 29.78 ? 496 ARG B NH2 1 ATOM 9405 N N . HIS B 1 477 ? -32.128 -25.355 20.900 1.00 21.38 ? 497 HIS B N 1 ATOM 9406 C CA . HIS B 1 477 ? -30.871 -24.665 21.218 1.00 21.37 ? 497 HIS B CA 1 ATOM 9407 C C . HIS B 1 477 ? -31.055 -23.199 21.641 1.00 21.23 ? 497 HIS B C 1 ATOM 9408 O O . HIS B 1 477 ? -30.118 -22.397 21.540 1.00 21.04 ? 497 HIS B O 1 ATOM 9409 C CB . HIS B 1 477 ? -29.939 -24.714 20.015 1.00 21.54 ? 497 HIS B CB 1 ATOM 9410 C CG . HIS B 1 477 ? -29.850 -26.062 19.382 1.00 21.52 ? 497 HIS B CG 1 ATOM 9411 N ND1 . HIS B 1 477 ? -28.903 -26.992 19.749 1.00 22.38 ? 497 HIS B ND1 1 ATOM 9412 C CD2 . HIS B 1 477 ? -30.606 -26.648 18.425 1.00 20.13 ? 497 HIS B CD2 1 ATOM 9413 C CE1 . HIS B 1 477 ? -29.061 -28.084 19.021 1.00 21.57 ? 497 HIS B CE1 1 ATOM 9414 N NE2 . HIS B 1 477 ? -30.097 -27.905 18.221 1.00 20.60 ? 497 HIS B NE2 1 ATOM 9415 N N . GLY B 1 478 ? -32.245 -22.858 22.125 1.00 20.54 ? 498 GLY B N 1 ATOM 9416 C CA . GLY B 1 478 ? -32.563 -21.474 22.432 1.00 20.09 ? 498 GLY B CA 1 ATOM 9417 C C . GLY B 1 478 ? -34.049 -21.196 22.554 1.00 19.77 ? 498 GLY B C 1 ATOM 9418 O O . GLY B 1 478 ? -34.873 -22.123 22.643 1.00 19.32 ? 498 GLY B O 1 ATOM 9419 N N . THR B 1 479 ? -34.376 -19.905 22.546 1.00 19.27 ? 499 THR B N 1 ATOM 9420 C CA . THR B 1 479 ? -35.728 -19.418 22.817 1.00 18.90 ? 499 THR B CA 1 ATOM 9421 C C . THR B 1 479 ? -36.194 -18.458 21.734 1.00 18.96 ? 499 THR B C 1 ATOM 9422 O O . THR B 1 479 ? -35.447 -17.581 21.301 1.00 18.45 ? 499 THR B O 1 ATOM 9423 C CB . THR B 1 479 ? -35.753 -18.658 24.152 1.00 18.89 ? 499 THR B CB 1 ATOM 9424 O OG1 . THR B 1 479 ? -35.237 -19.503 25.183 1.00 18.33 ? 499 THR B OG1 1 ATOM 9425 C CG2 . THR B 1 479 ? -37.171 -18.174 24.510 1.00 17.59 ? 499 THR B CG2 1 ATOM 9426 N N . ARG B 1 480 ? -37.444 -18.607 21.310 1.00 19.24 ? 500 ARG B N 1 ATOM 9427 C CA . ARG B 1 480 ? -38.032 -17.637 20.398 1.00 19.05 ? 500 ARG B CA 1 ATOM 9428 C C . ARG B 1 480 ? -38.286 -16.342 21.164 1.00 18.86 ? 500 ARG B C 1 ATOM 9429 O O . ARG B 1 480 ? -38.989 -16.346 22.167 1.00 18.73 ? 500 ARG B O 1 ATOM 9430 C CB . ARG B 1 480 ? -39.315 -18.179 19.786 1.00 19.25 ? 500 ARG B CB 1 ATOM 9431 C CG . ARG B 1 480 ? -39.817 -17.371 18.611 1.00 19.73 ? 500 ARG B CG 1 ATOM 9432 C CD . ARG B 1 480 ? -41.061 -18.003 18.029 1.00 19.44 ? 500 ARG B CD 1 ATOM 9433 N NE . ARG B 1 480 ? -41.443 -17.405 16.759 1.00 19.82 ? 500 ARG B NE 1 ATOM 9434 C CZ . ARG B 1 480 ? -42.495 -17.793 16.033 1.00 22.84 ? 500 ARG B CZ 1 ATOM 9435 N NH1 . ARG B 1 480 ? -43.286 -18.778 16.460 1.00 22.73 ? 500 ARG B NH1 1 ATOM 9436 N NH2 . ARG B 1 480 ? -42.765 -17.189 14.879 1.00 21.88 ? 500 ARG B NH2 1 ATOM 9437 N N . LEU B 1 481 ? -37.691 -15.252 20.676 1.00 18.93 ? 501 LEU B N 1 ATOM 9438 C CA . LEU B 1 481 ? -37.767 -13.920 21.291 1.00 19.24 ? 501 LEU B CA 1 ATOM 9439 C C . LEU B 1 481 ? -38.584 -12.906 20.479 1.00 19.22 ? 501 LEU B C 1 ATOM 9440 O O . LEU B 1 481 ? -39.008 -11.864 20.997 1.00 19.53 ? 501 LEU B O 1 ATOM 9441 C CB . LEU B 1 481 ? -36.352 -13.371 21.470 1.00 19.07 ? 501 LEU B CB 1 ATOM 9442 C CG . LEU B 1 481 ? -35.390 -14.262 22.247 1.00 18.81 ? 501 LEU B CG 1 ATOM 9443 C CD1 . LEU B 1 481 ? -34.077 -13.550 22.427 1.00 17.25 ? 501 LEU B CD1 1 ATOM 9444 C CD2 . LEU B 1 481 ? -35.988 -14.677 23.589 1.00 18.37 ? 501 LEU B CD2 1 ATOM 9445 N N . HIS B 1 482 ? -38.780 -13.205 19.205 1.00 19.22 ? 502 HIS B N 1 ATOM 9446 C CA . HIS B 1 482 ? -39.641 -12.418 18.346 1.00 19.68 ? 502 HIS B CA 1 ATOM 9447 C C . HIS B 1 482 ? -40.088 -13.302 17.182 1.00 19.60 ? 502 HIS B C 1 ATOM 9448 O O . HIS B 1 482 ? -39.756 -14.489 17.134 1.00 18.96 ? 502 HIS B O 1 ATOM 9449 C CB . HIS B 1 482 ? -38.918 -11.152 17.856 1.00 19.97 ? 502 HIS B CB 1 ATOM 9450 C CG . HIS B 1 482 ? -39.844 -10.016 17.552 1.00 20.89 ? 502 HIS B CG 1 ATOM 9451 N ND1 . HIS B 1 482 ? -40.389 -9.815 16.302 1.00 20.87 ? 502 HIS B ND1 1 ATOM 9452 C CD2 . HIS B 1 482 ? -40.344 -9.037 18.343 1.00 21.73 ? 502 HIS B CD2 1 ATOM 9453 C CE1 . HIS B 1 482 ? -41.189 -8.765 16.338 1.00 21.86 ? 502 HIS B CE1 1 ATOM 9454 N NE2 . HIS B 1 482 ? -41.173 -8.269 17.562 1.00 22.38 ? 502 HIS B NE2 1 ATOM 9455 N N . THR B 1 483 ? -40.855 -12.732 16.258 1.00 19.94 ? 503 THR B N 1 ATOM 9456 C CA . THR B 1 483 ? -41.438 -13.490 15.163 1.00 20.06 ? 503 THR B CA 1 ATOM 9457 C C . THR B 1 483 ? -40.396 -14.334 14.430 1.00 20.30 ? 503 THR B C 1 ATOM 9458 O O . THR B 1 483 ? -40.607 -15.529 14.217 1.00 20.96 ? 503 THR B O 1 ATOM 9459 C CB . THR B 1 483 ? -42.165 -12.562 14.179 1.00 20.29 ? 503 THR B CB 1 ATOM 9460 O OG1 . THR B 1 483 ? -43.138 -11.781 14.889 1.00 20.56 ? 503 THR B OG1 1 ATOM 9461 C CG2 . THR B 1 483 ? -42.855 -13.363 13.089 1.00 20.50 ? 503 THR B CG2 1 ATOM 9462 N N . HIS B 1 484 ? -39.267 -13.735 14.077 1.00 20.23 ? 504 HIS B N 1 ATOM 9463 C CA . HIS B 1 484 ? -38.265 -14.416 13.265 1.00 20.32 ? 504 HIS B CA 1 ATOM 9464 C C . HIS B 1 484 ? -36.943 -14.649 13.994 1.00 19.88 ? 504 HIS B C 1 ATOM 9465 O O . HIS B 1 484 ? -35.904 -14.863 13.352 1.00 19.62 ? 504 HIS B O 1 ATOM 9466 C CB . HIS B 1 484 ? -38.006 -13.594 11.997 1.00 20.56 ? 504 HIS B CB 1 ATOM 9467 C CG . HIS B 1 484 ? -39.222 -13.406 11.146 1.00 21.84 ? 504 HIS B CG 1 ATOM 9468 N ND1 . HIS B 1 484 ? -39.923 -14.464 10.606 1.00 22.11 ? 504 HIS B ND1 1 ATOM 9469 C CD2 . HIS B 1 484 ? -39.869 -12.284 10.752 1.00 22.50 ? 504 HIS B CD2 1 ATOM 9470 C CE1 . HIS B 1 484 ? -40.944 -13.998 9.907 1.00 23.25 ? 504 HIS B CE1 1 ATOM 9471 N NE2 . HIS B 1 484 ? -40.932 -12.679 9.979 1.00 22.90 ? 504 HIS B NE2 1 ATOM 9472 N N . LEU B 1 485 ? -36.985 -14.664 15.321 1.00 19.38 ? 505 LEU B N 1 ATOM 9473 C CA . LEU B 1 485 ? -35.764 -14.560 16.124 1.00 19.36 ? 505 LEU B CA 1 ATOM 9474 C C . LEU B 1 485 ? -35.640 -15.650 17.203 1.00 19.61 ? 505 LEU B C 1 ATOM 9475 O O . LEU B 1 485 ? -36.552 -15.834 18.033 1.00 19.38 ? 505 LEU B O 1 ATOM 9476 C CB . LEU B 1 485 ? -35.739 -13.174 16.780 1.00 19.32 ? 505 LEU B CB 1 ATOM 9477 C CG . LEU B 1 485 ? -34.496 -12.732 17.540 1.00 18.83 ? 505 LEU B CG 1 ATOM 9478 C CD1 . LEU B 1 485 ? -33.276 -12.659 16.599 1.00 17.71 ? 505 LEU B CD1 1 ATOM 9479 C CD2 . LEU B 1 485 ? -34.782 -11.386 18.206 1.00 17.79 ? 505 LEU B CD2 1 ATOM 9480 N N . ILE B 1 486 ? -34.507 -16.353 17.191 1.00 19.38 ? 506 ILE B N 1 ATOM 9481 C CA . ILE B 1 486 ? -34.154 -17.309 18.239 1.00 19.72 ? 506 ILE B CA 1 ATOM 9482 C C . ILE B 1 486 ? -32.976 -16.755 19.016 1.00 19.98 ? 506 ILE B C 1 ATOM 9483 O O . ILE B 1 486 ? -31.960 -16.388 18.425 1.00 19.84 ? 506 ILE B O 1 ATOM 9484 C CB . ILE B 1 486 ? -33.732 -18.684 17.680 1.00 19.80 ? 506 ILE B CB 1 ATOM 9485 C CG1 . ILE B 1 486 ? -34.955 -19.502 17.242 1.00 20.98 ? 506 ILE B CG1 1 ATOM 9486 C CG2 . ILE B 1 486 ? -32.891 -19.477 18.716 1.00 19.48 ? 506 ILE B CG2 1 ATOM 9487 C CD1 . ILE B 1 486 ? -35.575 -20.367 18.315 1.00 21.19 ? 506 ILE B CD1 1 ATOM 9488 N N . GLY B 1 487 ? -33.107 -16.706 20.341 1.00 19.97 ? 507 GLY B N 1 ATOM 9489 C CA . GLY B 1 487 ? -31.975 -16.378 21.202 1.00 20.04 ? 507 GLY B CA 1 ATOM 9490 C C . GLY B 1 487 ? -31.213 -17.646 21.510 1.00 19.43 ? 507 GLY B C 1 ATOM 9491 O O . GLY B 1 487 ? -31.696 -18.484 22.276 1.00 19.97 ? 507 GLY B O 1 ATOM 9492 N N . ASN B 1 488 ? -30.033 -17.803 20.919 1.00 18.36 ? 508 ASN B N 1 ATOM 9493 C CA . ASN B 1 488 ? -29.258 -19.033 21.115 1.00 18.12 ? 508 ASN B CA 1 ATOM 9494 C C . ASN B 1 488 ? -28.779 -19.208 22.544 1.00 17.79 ? 508 ASN B C 1 ATOM 9495 O O . ASN B 1 488 ? -28.336 -18.247 23.193 1.00 17.51 ? 508 ASN B O 1 ATOM 9496 C CB . ASN B 1 488 ? -28.043 -19.100 20.176 1.00 17.99 ? 508 ASN B CB 1 ATOM 9497 C CG . ASN B 1 488 ? -28.447 -19.146 18.713 1.00 18.59 ? 508 ASN B CG 1 ATOM 9498 O OD1 . ASN B 1 488 ? -29.120 -18.241 18.241 1.00 19.74 ? 508 ASN B OD1 1 ATOM 9499 N ND2 . ASN B 1 488 ? -28.040 -20.194 17.995 1.00 16.70 ? 508 ASN B ND2 1 ATOM 9500 N N . ILE B 1 489 ? -28.868 -20.447 23.020 1.00 17.50 ? 509 ILE B N 1 ATOM 9501 C CA . ILE B 1 489 ? -28.345 -20.806 24.325 1.00 17.98 ? 509 ILE B CA 1 ATOM 9502 C C . ILE B 1 489 ? -26.831 -20.656 24.296 1.00 17.86 ? 509 ILE B C 1 ATOM 9503 O O . ILE B 1 489 ? -26.193 -20.910 23.269 1.00 18.04 ? 509 ILE B O 1 ATOM 9504 C CB . ILE B 1 489 ? -28.732 -22.236 24.706 1.00 18.15 ? 509 ILE B CB 1 ATOM 9505 C CG1 . ILE B 1 489 ? -28.329 -22.530 26.150 1.00 19.31 ? 509 ILE B CG1 1 ATOM 9506 C CG2 . ILE B 1 489 ? -28.123 -23.264 23.711 1.00 17.61 ? 509 ILE B CG2 1 ATOM 9507 C CD1 . ILE B 1 489 ? -28.981 -23.806 26.711 1.00 20.41 ? 509 ILE B CD1 1 ATOM 9508 N N . HIS B 1 490 ? -26.268 -20.195 25.405 1.00 17.72 ? 510 HIS B N 1 ATOM 9509 C CA . HIS B 1 490 ? -24.824 -20.043 25.513 1.00 17.32 ? 510 HIS B CA 1 ATOM 9510 C C . HIS B 1 490 ? -24.387 -19.905 26.952 1.00 17.19 ? 510 HIS B C 1 ATOM 9511 O O . HIS B 1 490 ? -25.200 -19.618 27.832 1.00 16.83 ? 510 HIS B O 1 ATOM 9512 C CB . HIS B 1 490 ? -24.364 -18.812 24.729 1.00 17.46 ? 510 HIS B CB 1 ATOM 9513 C CG . HIS B 1 490 ? -24.996 -17.536 25.185 1.00 17.90 ? 510 HIS B CG 1 ATOM 9514 N ND1 . HIS B 1 490 ? -26.317 -17.226 24.931 1.00 17.50 ? 510 HIS B ND1 1 ATOM 9515 C CD2 . HIS B 1 490 ? -24.492 -16.496 25.892 1.00 17.72 ? 510 HIS B CD2 1 ATOM 9516 C CE1 . HIS B 1 490 ? -26.602 -16.053 25.469 1.00 17.05 ? 510 HIS B CE1 1 ATOM 9517 N NE2 . HIS B 1 490 ? -25.508 -15.584 26.050 1.00 17.43 ? 510 HIS B NE2 1 ATOM 9518 N N . THR B 1 491 ? -23.089 -20.096 27.176 1.00 17.13 ? 511 THR B N 1 ATOM 9519 C CA . THR B 1 491 ? -22.481 -19.833 28.460 1.00 16.81 ? 511 THR B CA 1 ATOM 9520 C C . THR B 1 491 ? -21.413 -18.741 28.326 1.00 17.51 ? 511 THR B C 1 ATOM 9521 O O . THR B 1 491 ? -20.581 -18.774 27.411 1.00 17.23 ? 511 THR B O 1 ATOM 9522 C CB . THR B 1 491 ? -21.845 -21.105 29.058 1.00 17.05 ? 511 THR B CB 1 ATOM 9523 O OG1 . THR B 1 491 ? -22.836 -22.131 29.160 1.00 17.08 ? 511 THR B OG1 1 ATOM 9524 C CG2 . THR B 1 491 ? -21.280 -20.823 30.460 1.00 15.34 ? 511 THR B CG2 1 ATOM 9525 N N . HIS B 1 492 ? -21.469 -17.772 29.237 1.00 17.57 ? 512 HIS B N 1 ATOM 9526 C CA . HIS B 1 492 ? -20.440 -16.754 29.380 1.00 18.22 ? 512 HIS B CA 1 ATOM 9527 C C . HIS B 1 492 ? -19.412 -17.262 30.377 1.00 18.45 ? 512 HIS B C 1 ATOM 9528 O O . HIS B 1 492 ? -19.784 -17.672 31.474 1.00 17.86 ? 512 HIS B O 1 ATOM 9529 C CB . HIS B 1 492 ? -21.018 -15.445 29.934 1.00 17.72 ? 512 HIS B CB 1 ATOM 9530 C CG . HIS B 1 492 ? -21.982 -14.756 29.022 1.00 18.19 ? 512 HIS B CG 1 ATOM 9531 N ND1 . HIS B 1 492 ? -21.586 -13.824 28.090 1.00 17.71 ? 512 HIS B ND1 1 ATOM 9532 C CD2 . HIS B 1 492 ? -23.332 -14.818 28.941 1.00 17.60 ? 512 HIS B CD2 1 ATOM 9533 C CE1 . HIS B 1 492 ? -22.647 -13.376 27.443 1.00 18.00 ? 512 HIS B CE1 1 ATOM 9534 N NE2 . HIS B 1 492 ? -23.719 -13.952 27.951 1.00 17.29 ? 512 HIS B NE2 1 ATOM 9535 N N . LEU B 1 493 ? -18.132 -17.221 30.010 1.00 18.96 ? 513 LEU B N 1 ATOM 9536 C CA . LEU B 1 493 ? -17.059 -17.568 30.947 1.00 19.54 ? 513 LEU B CA 1 ATOM 9537 C C . LEU B 1 493 ? -15.979 -16.524 30.844 1.00 19.66 ? 513 LEU B C 1 ATOM 9538 O O . LEU B 1 493 ? -15.624 -16.120 29.742 1.00 20.47 ? 513 LEU B O 1 ATOM 9539 C CB . LEU B 1 493 ? -16.444 -18.923 30.624 1.00 19.98 ? 513 LEU B CB 1 ATOM 9540 C CG . LEU B 1 493 ? -17.311 -20.175 30.695 1.00 20.67 ? 513 LEU B CG 1 ATOM 9541 C CD1 . LEU B 1 493 ? -16.601 -21.323 29.986 1.00 21.24 ? 513 LEU B CD1 1 ATOM 9542 C CD2 . LEU B 1 493 ? -17.637 -20.525 32.144 1.00 20.87 ? 513 LEU B CD2 1 ATOM 9543 N N . VAL B 1 494 ? -15.456 -16.101 31.992 1.00 19.48 ? 514 VAL B N 1 ATOM 9544 C CA . VAL B 1 494 ? -14.422 -15.084 32.070 1.00 19.28 ? 514 VAL B CA 1 ATOM 9545 C C . VAL B 1 494 ? -13.309 -15.640 32.941 1.00 19.40 ? 514 VAL B C 1 ATOM 9546 O O . VAL B 1 494 ? -13.576 -16.289 33.959 1.00 19.41 ? 514 VAL B O 1 ATOM 9547 C CB . VAL B 1 494 ? -14.956 -13.756 32.686 1.00 19.50 ? 514 VAL B CB 1 ATOM 9548 C CG1 . VAL B 1 494 ? -13.876 -12.677 32.684 1.00 18.34 ? 514 VAL B CG1 1 ATOM 9549 C CG2 . VAL B 1 494 ? -16.192 -13.262 31.930 1.00 19.06 ? 514 VAL B CG2 1 ATOM 9550 N N . HIS B 1 495 ? -12.069 -15.392 32.529 1.00 19.33 ? 515 HIS B N 1 ATOM 9551 C CA . HIS B 1 495 ? -10.897 -15.791 33.292 1.00 19.38 ? 515 HIS B CA 1 ATOM 9552 C C . HIS B 1 495 ? -10.159 -14.560 33.777 1.00 19.44 ? 515 HIS B C 1 ATOM 9553 O O . HIS B 1 495 ? -9.919 -13.630 32.999 1.00 19.56 ? 515 HIS B O 1 ATOM 9554 C CB . HIS B 1 495 ? -9.931 -16.624 32.453 1.00 19.33 ? 515 HIS B CB 1 ATOM 9555 C CG . HIS B 1 495 ? -9.093 -17.570 33.263 1.00 19.57 ? 515 HIS B CG 1 ATOM 9556 N ND1 . HIS B 1 495 ? -7.727 -17.694 33.099 1.00 20.28 ? 515 HIS B ND1 1 ATOM 9557 C CD2 . HIS B 1 495 ? -9.435 -18.447 34.236 1.00 19.39 ? 515 HIS B CD2 1 ATOM 9558 C CE1 . HIS B 1 495 ? -7.268 -18.610 33.933 1.00 20.53 ? 515 HIS B CE1 1 ATOM 9559 N NE2 . HIS B 1 495 ? -8.285 -19.082 34.636 1.00 20.17 ? 515 HIS B NE2 1 ATOM 9560 N N . TYR B 1 496 ? -9.795 -14.585 35.054 1.00 18.92 ? 516 TYR B N 1 ATOM 9561 C CA . TYR B 1 496 ? -9.026 -13.542 35.684 1.00 19.33 ? 516 TYR B CA 1 ATOM 9562 C C . TYR B 1 496 ? -7.705 -14.120 36.156 1.00 18.93 ? 516 TYR B C 1 ATOM 9563 O O . TYR B 1 496 ? -7.648 -15.260 36.614 1.00 19.51 ? 516 TYR B O 1 ATOM 9564 C CB . TYR B 1 496 ? -9.768 -13.012 36.917 1.00 19.05 ? 516 TYR B CB 1 ATOM 9565 C CG . TYR B 1 496 ? -10.931 -12.099 36.644 1.00 19.91 ? 516 TYR B CG 1 ATOM 9566 C CD1 . TYR B 1 496 ? -12.238 -12.591 36.551 1.00 20.41 ? 516 TYR B CD1 1 ATOM 9567 C CD2 . TYR B 1 496 ? -10.744 -10.732 36.551 1.00 20.18 ? 516 TYR B CD2 1 ATOM 9568 C CE1 . TYR B 1 496 ? -13.316 -11.727 36.333 1.00 19.38 ? 516 TYR B CE1 1 ATOM 9569 C CE2 . TYR B 1 496 ? -11.796 -9.883 36.342 1.00 19.08 ? 516 TYR B CE2 1 ATOM 9570 C CZ . TYR B 1 496 ? -13.080 -10.376 36.236 1.00 19.99 ? 516 TYR B CZ 1 ATOM 9571 O OH . TYR B 1 496 ? -14.112 -9.485 36.015 1.00 21.02 ? 516 TYR B OH 1 ATOM 9572 N N . ARG B 1 497 ? -6.653 -13.326 36.057 1.00 19.30 ? 517 ARG B N 1 ATOM 9573 C CA . ARG B 1 497 ? -5.370 -13.658 36.668 1.00 19.08 ? 517 ARG B CA 1 ATOM 9574 C C . ARG B 1 497 ? -5.306 -12.862 37.946 1.00 19.29 ? 517 ARG B C 1 ATOM 9575 O O . ARG B 1 497 ? -5.505 -11.648 37.925 1.00 19.10 ? 517 ARG B O 1 ATOM 9576 C CB . ARG B 1 497 ? -4.223 -13.252 35.758 1.00 19.37 ? 517 ARG B CB 1 ATOM 9577 C CG . ARG B 1 497 ? -2.810 -13.446 36.357 1.00 18.55 ? 517 ARG B CG 1 ATOM 9578 C CD . ARG B 1 497 ? -1.774 -12.893 35.410 1.00 20.03 ? 517 ARG B CD 1 ATOM 9579 N NE . ARG B 1 497 ? -0.418 -12.796 35.966 1.00 20.47 ? 517 ARG B NE 1 ATOM 9580 C CZ . ARG B 1 497 ? 0.460 -13.799 36.033 1.00 21.89 ? 517 ARG B CZ 1 ATOM 9581 N NH1 . ARG B 1 497 ? 0.151 -15.012 35.613 1.00 22.81 ? 517 ARG B NH1 1 ATOM 9582 N NH2 . ARG B 1 497 ? 1.665 -13.585 36.544 1.00 24.56 ? 517 ARG B NH2 1 ATOM 9583 N N . VAL B 1 498 ? -5.050 -13.542 39.062 1.00 19.63 ? 518 VAL B N 1 ATOM 9584 C CA . VAL B 1 498 ? -5.033 -12.884 40.370 1.00 19.54 ? 518 VAL B CA 1 ATOM 9585 C C . VAL B 1 498 ? -3.698 -13.193 41.041 1.00 19.80 ? 518 VAL B C 1 ATOM 9586 O O . VAL B 1 498 ? -3.562 -14.178 41.762 1.00 19.07 ? 518 VAL B O 1 ATOM 9587 C CB . VAL B 1 498 ? -6.230 -13.334 41.242 1.00 19.37 ? 518 VAL B CB 1 ATOM 9588 C CG1 . VAL B 1 498 ? -6.371 -12.452 42.463 1.00 18.96 ? 518 VAL B CG1 1 ATOM 9589 C CG2 . VAL B 1 498 ? -7.528 -13.301 40.421 1.00 19.30 ? 518 VAL B CG2 1 ATOM 9590 N N . ASP B 1 499 ? -2.707 -12.361 40.749 1.00 20.45 ? 519 ASP B N 1 ATOM 9591 C CA . ASP B 1 499 ? -1.361 -12.551 41.279 1.00 21.02 ? 519 ASP B CA 1 ATOM 9592 C C . ASP B 1 499 ? -1.336 -11.906 42.647 1.00 21.47 ? 519 ASP B C 1 ATOM 9593 O O . ASP B 1 499 ? -0.964 -10.742 42.806 1.00 21.39 ? 519 ASP B O 1 ATOM 9594 C CB . ASP B 1 499 ? -0.306 -11.941 40.358 1.00 20.75 ? 519 ASP B CB 1 ATOM 9595 C CG . ASP B 1 499 ? 1.122 -12.164 40.864 1.00 21.26 ? 519 ASP B CG 1 ATOM 9596 O OD1 . ASP B 1 499 ? 1.303 -12.888 41.866 1.00 20.66 ? 519 ASP B OD1 1 ATOM 9597 O OD2 . ASP B 1 499 ? 2.063 -11.609 40.257 1.00 22.09 ? 519 ASP B OD2 1 ATOM 9598 N N . LEU B 1 500 ? -1.799 -12.654 43.635 1.00 22.41 ? 520 LEU B N 1 ATOM 9599 C CA . LEU B 1 500 ? -1.801 -12.149 44.998 1.00 23.06 ? 520 LEU B CA 1 ATOM 9600 C C . LEU B 1 500 ? -0.369 -12.222 45.496 1.00 22.93 ? 520 LEU B C 1 ATOM 9601 O O . LEU B 1 500 ? 0.312 -13.214 45.264 1.00 22.01 ? 520 LEU B O 1 ATOM 9602 C CB . LEU B 1 500 ? -2.713 -12.978 45.899 1.00 23.16 ? 520 LEU B CB 1 ATOM 9603 C CG . LEU B 1 500 ? -4.209 -12.859 45.600 1.00 24.41 ? 520 LEU B CG 1 ATOM 9604 C CD1 . LEU B 1 500 ? -4.980 -13.871 46.428 1.00 24.07 ? 520 LEU B CD1 1 ATOM 9605 C CD2 . LEU B 1 500 ? -4.705 -11.453 45.852 1.00 24.16 ? 520 LEU B CD2 1 ATOM 9606 N N . ASP B 1 501 ? 0.076 -11.153 46.146 1.00 23.61 ? 521 ASP B N 1 ATOM 9607 C CA . ASP B 1 501 ? 1.330 -11.130 46.880 1.00 24.09 ? 521 ASP B CA 1 ATOM 9608 C C . ASP B 1 501 ? 0.981 -10.657 48.300 1.00 24.22 ? 521 ASP B C 1 ATOM 9609 O O . ASP B 1 501 ? 1.154 -9.485 48.639 1.00 24.20 ? 521 ASP B O 1 ATOM 9610 C CB . ASP B 1 501 ? 2.335 -10.178 46.219 1.00 24.04 ? 521 ASP B CB 1 ATOM 9611 C CG . ASP B 1 501 ? 2.977 -10.747 44.940 1.00 24.71 ? 521 ASP B CG 1 ATOM 9612 O OD1 . ASP B 1 501 ? 2.702 -11.899 44.503 1.00 24.93 ? 521 ASP B OD1 1 ATOM 9613 O OD2 . ASP B 1 501 ? 3.783 -10.003 44.355 1.00 23.98 ? 521 ASP B OD2 1 ATOM 9614 N N . VAL B 1 502 ? 0.462 -11.570 49.117 1.00 24.71 ? 522 VAL B N 1 ATOM 9615 C CA . VAL B 1 502 ? -0.038 -11.205 50.440 1.00 25.00 ? 522 VAL B CA 1 ATOM 9616 C C . VAL B 1 502 ? 1.132 -10.784 51.356 1.00 26.06 ? 522 VAL B C 1 ATOM 9617 O O . VAL B 1 502 ? 1.977 -11.606 51.727 1.00 25.93 ? 522 VAL B O 1 ATOM 9618 C CB . VAL B 1 502 ? -0.847 -12.344 51.083 1.00 25.12 ? 522 VAL B CB 1 ATOM 9619 C CG1 . VAL B 1 502 ? -1.406 -11.902 52.443 1.00 23.56 ? 522 VAL B CG1 1 ATOM 9620 C CG2 . VAL B 1 502 ? -1.988 -12.791 50.150 1.00 24.76 ? 522 VAL B CG2 1 ATOM 9621 N N . ALA B 1 503 ? 1.172 -9.493 51.683 1.00 27.05 ? 523 ALA B N 1 ATOM 9622 C CA . ALA B 1 503 ? 2.232 -8.894 52.505 1.00 28.27 ? 523 ALA B CA 1 ATOM 9623 C C . ALA B 1 503 ? 3.637 -9.155 51.950 1.00 29.34 ? 523 ALA B C 1 ATOM 9624 O O . ALA B 1 503 ? 4.611 -9.124 52.693 1.00 29.56 ? 523 ALA B O 1 ATOM 9625 C CB . ALA B 1 503 ? 2.133 -9.398 53.943 1.00 27.86 ? 523 ALA B CB 1 ATOM 9626 N N . GLY B 1 504 ? 3.751 -9.401 50.648 1.00 30.68 ? 524 GLY B N 1 ATOM 9627 C CA . GLY B 1 504 ? 5.011 -9.890 50.096 1.00 31.40 ? 524 GLY B CA 1 ATOM 9628 C C . GLY B 1 504 ? 4.839 -10.960 49.038 1.00 32.11 ? 524 GLY B C 1 ATOM 9629 O O . GLY B 1 504 ? 3.746 -11.513 48.848 1.00 32.51 ? 524 GLY B O 1 ATOM 9630 N N . THR B 1 505 ? 5.946 -11.271 48.374 1.00 32.35 ? 525 THR B N 1 ATOM 9631 C CA A THR B 1 505 ? 5.917 -12.140 47.212 0.60 32.45 ? 525 THR B CA 1 ATOM 9632 C CA B THR B 1 505 ? 5.933 -12.153 47.211 0.40 32.44 ? 525 THR B CA 1 ATOM 9633 C C . THR B 1 505 ? 5.637 -13.595 47.571 1.00 32.43 ? 525 THR B C 1 ATOM 9634 O O . THR B 1 505 ? 4.929 -14.284 46.840 1.00 32.83 ? 525 THR B O 1 ATOM 9635 C CB A THR B 1 505 ? 7.236 -12.030 46.419 0.60 32.60 ? 525 THR B CB 1 ATOM 9636 C CB B THR B 1 505 ? 7.274 -12.110 46.428 0.40 32.55 ? 525 THR B CB 1 ATOM 9637 O OG1 A THR B 1 505 ? 7.655 -10.658 46.383 0.60 32.23 ? 525 THR B OG1 1 ATOM 9638 O OG1 B THR B 1 505 ? 7.212 -13.021 45.324 0.40 32.65 ? 525 THR B OG1 1 ATOM 9639 C CG2 A THR B 1 505 ? 7.050 -12.536 44.997 0.60 32.63 ? 525 THR B CG2 1 ATOM 9640 C CG2 B THR B 1 505 ? 8.455 -12.486 47.320 0.40 32.31 ? 525 THR B CG2 1 ATOM 9641 N N . LYS B 1 506 ? 6.173 -14.061 48.697 1.00 32.25 ? 526 LYS B N 1 ATOM 9642 C CA . LYS B 1 506 ? 6.115 -15.497 49.004 1.00 31.86 ? 526 LYS B CA 1 ATOM 9643 C C . LYS B 1 506 ? 4.966 -15.891 49.926 1.00 30.87 ? 526 LYS B C 1 ATOM 9644 O O . LYS B 1 506 ? 4.873 -15.426 51.061 1.00 30.96 ? 526 LYS B O 1 ATOM 9645 C CB . LYS B 1 506 ? 7.456 -15.994 49.542 1.00 32.22 ? 526 LYS B CB 1 ATOM 9646 C CG . LYS B 1 506 ? 8.529 -16.097 48.455 1.00 33.29 ? 526 LYS B CG 1 ATOM 9647 C CD . LYS B 1 506 ? 9.630 -17.067 48.847 1.00 35.42 ? 526 LYS B CD 1 ATOM 9648 C CE . LYS B 1 506 ? 10.655 -17.232 47.724 1.00 36.59 ? 526 LYS B CE 1 ATOM 9649 N NZ . LYS B 1 506 ? 11.521 -18.438 47.934 1.00 37.14 ? 526 LYS B NZ 1 ATOM 9650 N N . ASN B 1 507 ? 4.110 -16.773 49.410 1.00 29.56 ? 527 ASN B N 1 ATOM 9651 C CA . ASN B 1 507 ? 2.876 -17.164 50.058 1.00 28.41 ? 527 ASN B CA 1 ATOM 9652 C C . ASN B 1 507 ? 2.707 -18.670 50.035 1.00 28.04 ? 527 ASN B C 1 ATOM 9653 O O . ASN B 1 507 ? 3.436 -19.392 49.340 1.00 27.62 ? 527 ASN B O 1 ATOM 9654 C CB . ASN B 1 507 ? 1.674 -16.539 49.336 1.00 28.04 ? 527 ASN B CB 1 ATOM 9655 C CG . ASN B 1 507 ? 1.637 -15.021 49.427 1.00 27.19 ? 527 ASN B CG 1 ATOM 9656 O OD1 . ASN B 1 507 ? 1.142 -14.354 48.518 1.00 25.45 ? 527 ASN B OD1 1 ATOM 9657 N ND2 . ASN B 1 507 ? 2.146 -14.471 50.514 1.00 26.35 ? 527 ASN B ND2 1 ATOM 9658 N N . SER B 1 508 ? 1.730 -19.134 50.804 1.00 27.44 ? 528 SER B N 1 ATOM 9659 C CA . SER B 1 508 ? 1.211 -20.481 50.666 1.00 27.43 ? 528 SER B CA 1 ATOM 9660 C C . SER B 1 508 ? -0.307 -20.404 50.420 1.00 26.71 ? 528 SER B C 1 ATOM 9661 O O . SER B 1 508 ? -0.903 -19.332 50.497 1.00 26.31 ? 528 SER B O 1 ATOM 9662 C CB . SER B 1 508 ? 1.567 -21.315 51.898 1.00 27.59 ? 528 SER B CB 1 ATOM 9663 O OG . SER B 1 508 ? 2.982 -21.588 51.930 1.00 30.03 ? 528 SER B OG 1 ATOM 9664 N N . PHE B 1 509 ? -0.903 -21.534 50.074 1.00 26.12 ? 529 PHE B N 1 ATOM 9665 C CA . PHE B 1 509 ? -2.340 -21.632 49.842 1.00 26.01 ? 529 PHE B CA 1 ATOM 9666 C C . PHE B 1 509 ? -2.890 -22.674 50.807 1.00 26.12 ? 529 PHE B C 1 ATOM 9667 O O . PHE B 1 509 ? -2.309 -23.750 50.986 1.00 26.29 ? 529 PHE B O 1 ATOM 9668 C CB . PHE B 1 509 ? -2.657 -22.021 48.390 1.00 25.75 ? 529 PHE B CB 1 ATOM 9669 C CG . PHE B 1 509 ? -4.110 -22.347 48.147 1.00 24.75 ? 529 PHE B CG 1 ATOM 9670 C CD1 . PHE B 1 509 ? -5.074 -21.355 48.184 1.00 24.50 ? 529 PHE B CD1 1 ATOM 9671 C CD2 . PHE B 1 509 ? -4.512 -23.649 47.862 1.00 25.55 ? 529 PHE B CD2 1 ATOM 9672 C CE1 . PHE B 1 509 ? -6.420 -21.652 47.954 1.00 24.22 ? 529 PHE B CE1 1 ATOM 9673 C CE2 . PHE B 1 509 ? -5.856 -23.952 47.630 1.00 24.74 ? 529 PHE B CE2 1 ATOM 9674 C CZ . PHE B 1 509 ? -6.806 -22.951 47.678 1.00 24.35 ? 529 PHE B CZ 1 ATOM 9675 N N . GLN B 1 510 ? -4.024 -22.344 51.403 1.00 25.84 ? 530 GLN B N 1 ATOM 9676 C CA . GLN B 1 510 ? -4.616 -23.133 52.464 1.00 25.95 ? 530 GLN B CA 1 ATOM 9677 C C . GLN B 1 510 ? -6.126 -22.956 52.356 1.00 25.02 ? 530 GLN B C 1 ATOM 9678 O O . GLN B 1 510 ? -6.596 -21.899 51.963 1.00 25.34 ? 530 GLN B O 1 ATOM 9679 C CB . GLN B 1 510 ? -4.084 -22.592 53.803 1.00 26.27 ? 530 GLN B CB 1 ATOM 9680 C CG . GLN B 1 510 ? -4.779 -23.082 55.060 1.00 28.59 ? 530 GLN B CG 1 ATOM 9681 C CD . GLN B 1 510 ? -4.449 -22.232 56.292 1.00 30.09 ? 530 GLN B CD 1 ATOM 9682 O OE1 . GLN B 1 510 ? -4.042 -21.075 56.185 1.00 33.29 ? 530 GLN B OE1 1 ATOM 9683 N NE2 . GLN B 1 510 ? -4.648 -22.805 57.460 1.00 32.25 ? 530 GLN B NE2 1 ATOM 9684 N N . THR B 1 511 ? -6.881 -23.988 52.686 1.00 24.60 ? 531 THR B N 1 ATOM 9685 C CA . THR B 1 511 ? -8.325 -23.876 52.777 1.00 24.16 ? 531 THR B CA 1 ATOM 9686 C C . THR B 1 511 ? -8.800 -24.297 54.166 1.00 24.24 ? 531 THR B C 1 ATOM 9687 O O . THR B 1 511 ? -8.156 -25.111 54.847 1.00 24.29 ? 531 THR B O 1 ATOM 9688 C CB . THR B 1 511 ? -9.059 -24.727 51.698 1.00 24.17 ? 531 THR B CB 1 ATOM 9689 O OG1 . THR B 1 511 ? -8.791 -26.120 51.898 1.00 24.08 ? 531 THR B OG1 1 ATOM 9690 C CG2 . THR B 1 511 ? -8.635 -24.314 50.272 1.00 23.57 ? 531 THR B CG2 1 ATOM 9691 N N . LEU B 1 512 ? -9.937 -23.741 54.571 1.00 23.64 ? 532 LEU B N 1 ATOM 9692 C CA . LEU B 1 512 ? -10.576 -24.087 55.828 1.00 23.30 ? 532 LEU B CA 1 ATOM 9693 C C . LEU B 1 512 ? -12.004 -24.578 55.561 1.00 23.35 ? 532 LEU B C 1 ATOM 9694 O O . LEU B 1 512 ? -12.696 -24.043 54.687 1.00 22.77 ? 532 LEU B O 1 ATOM 9695 C CB . LEU B 1 512 ? -10.608 -22.882 56.781 1.00 22.85 ? 532 LEU B CB 1 ATOM 9696 C CG . LEU B 1 512 ? -9.319 -22.085 57.005 1.00 22.62 ? 532 LEU B CG 1 ATOM 9697 C CD1 . LEU B 1 512 ? -9.589 -20.901 57.918 1.00 21.25 ? 532 LEU B CD1 1 ATOM 9698 C CD2 . LEU B 1 512 ? -8.197 -22.962 57.569 1.00 20.05 ? 532 LEU B CD2 1 ATOM 9699 N N . GLN B 1 513 ? -12.421 -25.588 56.322 1.00 23.32 ? 533 GLN B N 1 ATOM 9700 C CA . GLN B 1 513 ? -13.774 -26.134 56.268 1.00 23.82 ? 533 GLN B CA 1 ATOM 9701 C C . GLN B 1 513 ? -14.308 -26.321 57.685 1.00 24.12 ? 533 GLN B C 1 ATOM 9702 O O . GLN B 1 513 ? -13.552 -26.297 58.653 1.00 23.96 ? 533 GLN B O 1 ATOM 9703 C CB . GLN B 1 513 ? -13.785 -27.485 55.546 1.00 23.57 ? 533 GLN B CB 1 ATOM 9704 N N . MET B 1 514 ? -15.617 -26.491 57.802 1.00 24.65 ? 534 MET B N 1 ATOM 9705 C CA . MET B 1 514 ? -16.210 -26.908 59.054 1.00 25.29 ? 534 MET B CA 1 ATOM 9706 C C . MET B 1 514 ? -16.358 -28.415 58.998 1.00 25.29 ? 534 MET B C 1 ATOM 9707 O O . MET B 1 514 ? -16.868 -28.948 58.017 1.00 25.64 ? 534 MET B O 1 ATOM 9708 C CB . MET B 1 514 ? -17.576 -26.249 59.261 1.00 25.65 ? 534 MET B CB 1 ATOM 9709 C CG . MET B 1 514 ? -18.164 -26.471 60.642 1.00 27.08 ? 534 MET B CG 1 ATOM 9710 S SD . MET B 1 514 ? -19.156 -27.984 60.833 1.00 31.03 ? 534 MET B SD 1 ATOM 9711 C CE . MET B 1 514 ? -20.597 -27.606 59.836 1.00 29.48 ? 534 MET B CE 1 ATOM 9712 N N . LYS B 1 515 ? -15.918 -29.093 60.055 1.00 25.28 ? 535 LYS B N 1 ATOM 9713 C CA . LYS B 1 515 ? -16.071 -30.534 60.195 1.00 25.36 ? 535 LYS B CA 1 ATOM 9714 C C . LYS B 1 515 ? -16.688 -30.818 61.553 1.00 25.24 ? 535 LYS B C 1 ATOM 9715 O O . LYS B 1 515 ? -16.250 -30.261 62.561 1.00 25.32 ? 535 LYS B O 1 ATOM 9716 C CB . LYS B 1 515 ? -14.707 -31.219 60.108 1.00 25.53 ? 535 LYS B CB 1 ATOM 9717 C CG . LYS B 1 515 ? -14.761 -32.729 60.183 1.00 27.04 ? 535 LYS B CG 1 ATOM 9718 N N . LEU B 1 516 ? -17.698 -31.678 61.589 1.00 24.58 ? 536 LEU B N 1 ATOM 9719 C CA . LEU B 1 516 ? -18.365 -31.968 62.837 1.00 24.53 ? 536 LEU B CA 1 ATOM 9720 C C . LEU B 1 516 ? -17.554 -32.957 63.665 1.00 24.60 ? 536 LEU B C 1 ATOM 9721 O O . LEU B 1 516 ? -16.888 -33.829 63.123 1.00 24.55 ? 536 LEU B O 1 ATOM 9722 C CB . LEU B 1 516 ? -19.753 -32.551 62.587 1.00 24.40 ? 536 LEU B CB 1 ATOM 9723 C CG . LEU B 1 516 ? -20.819 -31.624 61.998 1.00 23.73 ? 536 LEU B CG 1 ATOM 9724 C CD1 . LEU B 1 516 ? -22.068 -32.453 61.724 1.00 22.03 ? 536 LEU B CD1 1 ATOM 9725 C CD2 . LEU B 1 516 ? -21.127 -30.459 62.932 1.00 22.17 ? 536 LEU B CD2 1 ATOM 9726 N N . GLU B 1 517 ? -17.622 -32.820 64.983 1.00 24.70 ? 537 GLU B N 1 ATOM 9727 C CA . GLU B 1 517 ? -17.172 -33.877 65.875 1.00 24.77 ? 537 GLU B CA 1 ATOM 9728 C C . GLU B 1 517 ? -18.368 -34.344 66.677 1.00 25.24 ? 537 GLU B C 1 ATOM 9729 O O . GLU B 1 517 ? -19.353 -33.618 66.819 1.00 25.19 ? 537 GLU B O 1 ATOM 9730 C CB . GLU B 1 517 ? -16.063 -33.392 66.805 1.00 24.48 ? 537 GLU B CB 1 ATOM 9731 C CG . GLU B 1 517 ? -16.519 -32.378 67.853 1.00 24.32 ? 537 GLU B CG 1 ATOM 9732 C CD . GLU B 1 517 ? -15.393 -31.933 68.764 1.00 23.71 ? 537 GLU B CD 1 ATOM 9733 O OE1 . GLU B 1 517 ? -14.259 -32.397 68.571 1.00 23.18 ? 537 GLU B OE1 1 ATOM 9734 O OE2 . GLU B 1 517 ? -15.650 -31.124 69.673 1.00 23.96 ? 537 GLU B OE2 1 ATOM 9735 N N . ASN B 1 518 ? -18.269 -35.567 67.187 1.00 25.71 ? 538 ASN B N 1 ATOM 9736 C CA . ASN B 1 518 ? -19.286 -36.155 68.023 1.00 26.05 ? 538 ASN B CA 1 ATOM 9737 C C . ASN B 1 518 ? -18.626 -36.652 69.306 1.00 26.43 ? 538 ASN B C 1 ATOM 9738 O O . ASN B 1 518 ? -18.005 -37.717 69.310 1.00 26.45 ? 538 ASN B O 1 ATOM 9739 C CB . ASN B 1 518 ? -19.939 -37.296 67.270 1.00 26.16 ? 538 ASN B CB 1 ATOM 9740 C CG . ASN B 1 518 ? -20.980 -38.019 68.082 1.00 26.73 ? 538 ASN B CG 1 ATOM 9741 O OD1 . ASN B 1 518 ? -21.216 -37.723 69.256 1.00 25.89 ? 538 ASN B OD1 1 ATOM 9742 N ND2 . ASN B 1 518 ? -21.613 -38.989 67.445 1.00 27.85 ? 538 ASN B ND2 1 ATOM 9743 N N . ILE B 1 519 ? -18.748 -35.872 70.384 1.00 26.33 ? 539 ILE B N 1 ATOM 9744 C CA . ILE B 1 519 ? -18.070 -36.191 71.643 1.00 26.31 ? 539 ILE B CA 1 ATOM 9745 C C . ILE B 1 519 ? -19.058 -36.437 72.760 1.00 26.31 ? 539 ILE B C 1 ATOM 9746 O O . ILE B 1 519 ? -20.246 -36.163 72.625 1.00 26.52 ? 539 ILE B O 1 ATOM 9747 C CB . ILE B 1 519 ? -17.075 -35.075 72.071 1.00 26.16 ? 539 ILE B CB 1 ATOM 9748 C CG1 . ILE B 1 519 ? -17.800 -33.747 72.351 1.00 26.48 ? 539 ILE B CG1 1 ATOM 9749 C CG2 . ILE B 1 519 ? -16.024 -34.876 70.997 1.00 26.26 ? 539 ILE B CG2 1 ATOM 9750 C CD1 . ILE B 1 519 ? -16.891 -32.628 72.827 1.00 23.61 ? 539 ILE B CD1 1 ATOM 9751 N N . THR B 1 520 ? -18.553 -36.974 73.865 1.00 26.26 ? 540 THR B N 1 ATOM 9752 C CA . THR B 1 520 ? -19.326 -37.057 75.092 1.00 26.42 ? 540 THR B CA 1 ATOM 9753 C C . THR B 1 520 ? -19.577 -35.632 75.589 1.00 26.43 ? 540 THR B C 1 ATOM 9754 O O . THR B 1 520 ? -18.658 -34.817 75.636 1.00 25.83 ? 540 THR B O 1 ATOM 9755 C CB . THR B 1 520 ? -18.572 -37.833 76.189 1.00 26.44 ? 540 THR B CB 1 ATOM 9756 O OG1 . THR B 1 520 ? -18.199 -39.127 75.693 1.00 26.70 ? 540 THR B OG1 1 ATOM 9757 C CG2 . THR B 1 520 ? -19.442 -37.995 77.436 1.00 25.99 ? 540 THR B CG2 1 ATOM 9758 N N . ASN B 1 521 ? -20.826 -35.333 75.923 1.00 26.43 ? 541 ASN B N 1 ATOM 9759 C CA . ASN B 1 521 ? -21.152 -34.056 76.528 1.00 26.76 ? 541 ASN B CA 1 ATOM 9760 C C . ASN B 1 521 ? -20.388 -33.953 77.860 1.00 27.02 ? 541 ASN B C 1 ATOM 9761 O O . ASN B 1 521 ? -20.675 -34.697 78.790 1.00 27.05 ? 541 ASN B O 1 ATOM 9762 C CB . ASN B 1 521 ? -22.662 -33.954 76.744 1.00 26.54 ? 541 ASN B CB 1 ATOM 9763 C CG . ASN B 1 521 ? -23.070 -32.659 77.427 1.00 26.68 ? 541 ASN B CG 1 ATOM 9764 O OD1 . ASN B 1 521 ? -22.309 -32.094 78.202 1.00 26.24 ? 541 ASN B OD1 1 ATOM 9765 N ND2 . ASN B 1 521 ? -24.277 -32.187 77.135 1.00 26.23 ? 541 ASN B ND2 1 ATOM 9766 N N . PRO B 1 522 ? -19.411 -33.036 77.953 1.00 27.58 ? 542 PRO B N 1 ATOM 9767 C CA . PRO B 1 522 ? -18.555 -33.005 79.138 1.00 28.00 ? 542 PRO B CA 1 ATOM 9768 C C . PRO B 1 522 ? -19.241 -32.629 80.450 1.00 28.28 ? 542 PRO B C 1 ATOM 9769 O O . PRO B 1 522 ? -18.611 -32.756 81.488 1.00 28.89 ? 542 PRO B O 1 ATOM 9770 C CB . PRO B 1 522 ? -17.491 -31.962 78.784 1.00 28.14 ? 542 PRO B CB 1 ATOM 9771 C CG . PRO B 1 522 ? -18.105 -31.116 77.770 1.00 28.22 ? 542 PRO B CG 1 ATOM 9772 C CD . PRO B 1 522 ? -19.063 -31.970 77.000 1.00 27.63 ? 542 PRO B CD 1 ATOM 9773 N N . TRP B 1 523 ? -20.500 -32.183 80.416 1.00 28.27 ? 543 TRP B N 1 ATOM 9774 C CA . TRP B 1 523 ? -21.250 -31.867 81.642 1.00 28.15 ? 543 TRP B CA 1 ATOM 9775 C C . TRP B 1 523 ? -22.513 -32.711 81.827 1.00 28.53 ? 543 TRP B C 1 ATOM 9776 O O . TRP B 1 523 ? -23.245 -32.537 82.800 1.00 28.19 ? 543 TRP B O 1 ATOM 9777 C CB . TRP B 1 523 ? -21.602 -30.371 81.690 1.00 28.06 ? 543 TRP B CB 1 ATOM 9778 C CG . TRP B 1 523 ? -22.296 -29.852 80.471 1.00 26.42 ? 543 TRP B CG 1 ATOM 9779 C CD1 . TRP B 1 523 ? -21.711 -29.349 79.352 1.00 25.60 ? 543 TRP B CD1 1 ATOM 9780 C CD2 . TRP B 1 523 ? -23.706 -29.780 80.257 1.00 24.66 ? 543 TRP B CD2 1 ATOM 9781 N NE1 . TRP B 1 523 ? -22.670 -28.961 78.454 1.00 25.40 ? 543 TRP B NE1 1 ATOM 9782 C CE2 . TRP B 1 523 ? -23.904 -29.218 78.983 1.00 23.93 ? 543 TRP B CE2 1 ATOM 9783 C CE3 . TRP B 1 523 ? -24.822 -30.126 81.026 1.00 23.89 ? 543 TRP B CE3 1 ATOM 9784 C CZ2 . TRP B 1 523 ? -25.171 -28.995 78.450 1.00 24.22 ? 543 TRP B CZ2 1 ATOM 9785 C CZ3 . TRP B 1 523 ? -26.086 -29.904 80.497 1.00 25.21 ? 543 TRP B CZ3 1 ATOM 9786 C CH2 . TRP B 1 523 ? -26.247 -29.342 79.217 1.00 24.48 ? 543 TRP B CH2 1 ATOM 9787 N N . SER B 1 524 ? -22.767 -33.619 80.889 1.00 28.99 ? 544 SER B N 1 ATOM 9788 C CA . SER B 1 524 ? -23.864 -34.570 80.995 1.00 28.98 ? 544 SER B CA 1 ATOM 9789 C C . SER B 1 524 ? -23.416 -35.828 80.242 1.00 29.65 ? 544 SER B C 1 ATOM 9790 O O . SER B 1 524 ? -23.806 -36.035 79.081 1.00 29.53 ? 544 SER B O 1 ATOM 9791 C CB . SER B 1 524 ? -25.146 -33.978 80.415 1.00 28.91 ? 544 SER B CB 1 ATOM 9792 O OG . SER B 1 524 ? -26.248 -34.857 80.554 1.00 27.89 ? 544 SER B OG 1 ATOM 9793 N N . PRO B 1 525 ? -22.578 -36.663 80.903 1.00 30.30 ? 545 PRO B N 1 ATOM 9794 C CA . PRO B 1 525 ? -21.865 -37.820 80.314 1.00 30.43 ? 545 PRO B CA 1 ATOM 9795 C C . PRO B 1 525 ? -22.735 -38.799 79.530 1.00 30.20 ? 545 PRO B C 1 ATOM 9796 O O . PRO B 1 525 ? -22.249 -39.439 78.604 1.00 30.47 ? 545 PRO B O 1 ATOM 9797 C CB . PRO B 1 525 ? -21.258 -38.542 81.527 1.00 30.80 ? 545 PRO B CB 1 ATOM 9798 C CG . PRO B 1 525 ? -21.389 -37.628 82.688 1.00 30.70 ? 545 PRO B CG 1 ATOM 9799 C CD . PRO B 1 525 ? -22.278 -36.491 82.341 1.00 30.56 ? 545 PRO B CD 1 ATOM 9800 N N . ARG B 1 526 ? -24.007 -38.913 79.894 1.00 29.98 ? 546 ARG B N 1 ATOM 9801 C CA . ARG B 1 526 ? -24.927 -39.789 79.183 1.00 29.86 ? 546 ARG B CA 1 ATOM 9802 C C . ARG B 1 526 ? -25.382 -39.208 77.843 1.00 29.56 ? 546 ARG B C 1 ATOM 9803 O O . ARG B 1 526 ? -26.132 -39.853 77.117 1.00 29.86 ? 546 ARG B O 1 ATOM 9804 C CB . ARG B 1 526 ? -26.151 -40.090 80.050 1.00 29.93 ? 546 ARG B CB 1 ATOM 9805 C CG . ARG B 1 526 ? -25.810 -40.751 81.385 1.00 30.74 ? 546 ARG B CG 1 ATOM 9806 C CD . ARG B 1 526 ? -27.073 -41.057 82.192 1.00 32.05 ? 546 ARG B CD 1 ATOM 9807 N N . HIS B 1 527 ? -24.943 -37.995 77.516 1.00 28.92 ? 547 HIS B N 1 ATOM 9808 C CA . HIS B 1 527 ? -25.372 -37.328 76.295 1.00 28.46 ? 547 HIS B CA 1 ATOM 9809 C C . HIS B 1 527 ? -24.181 -37.017 75.408 1.00 27.76 ? 547 HIS B C 1 ATOM 9810 O O . HIS B 1 527 ? -23.036 -37.220 75.802 1.00 27.39 ? 547 HIS B O 1 ATOM 9811 C CB . HIS B 1 527 ? -26.161 -36.067 76.646 1.00 28.40 ? 547 HIS B CB 1 ATOM 9812 C CG . HIS B 1 527 ? -27.372 -36.357 77.473 1.00 29.33 ? 547 HIS B CG 1 ATOM 9813 N ND1 . HIS B 1 527 ? -27.356 -36.332 78.850 1.00 30.04 ? 547 HIS B ND1 1 ATOM 9814 C CD2 . HIS B 1 527 ? -28.619 -36.741 77.118 1.00 30.18 ? 547 HIS B CD2 1 ATOM 9815 C CE1 . HIS B 1 527 ? -28.548 -36.667 79.307 1.00 30.17 ? 547 HIS B CE1 1 ATOM 9816 N NE2 . HIS B 1 527 ? -29.333 -36.921 78.276 1.00 29.97 ? 547 HIS B NE2 1 ATOM 9817 N N . ARG B 1 528 ? -24.475 -36.547 74.203 1.00 27.24 ? 548 ARG B N 1 ATOM 9818 C CA . ARG B 1 528 ? -23.467 -36.282 73.192 1.00 26.83 ? 548 ARG B CA 1 ATOM 9819 C C . ARG B 1 528 ? -23.491 -34.816 72.800 1.00 26.23 ? 548 ARG B C 1 ATOM 9820 O O . ARG B 1 528 ? -24.546 -34.187 72.810 1.00 26.45 ? 548 ARG B O 1 ATOM 9821 C CB . ARG B 1 528 ? -23.761 -37.101 71.926 1.00 27.00 ? 548 ARG B CB 1 ATOM 9822 C CG . ARG B 1 528 ? -24.092 -38.565 72.137 1.00 27.21 ? 548 ARG B CG 1 ATOM 9823 C CD . ARG B 1 528 ? -22.935 -39.329 72.708 1.00 27.53 ? 548 ARG B CD 1 ATOM 9824 N NE . ARG B 1 528 ? -21.714 -39.194 71.918 1.00 28.48 ? 548 ARG B NE 1 ATOM 9825 C CZ . ARG B 1 528 ? -20.536 -39.690 72.291 1.00 29.29 ? 548 ARG B CZ 1 ATOM 9826 N NH1 . ARG B 1 528 ? -20.424 -40.368 73.431 1.00 29.84 ? 548 ARG B NH1 1 ATOM 9827 N NH2 . ARG B 1 528 ? -19.467 -39.510 71.526 1.00 29.20 ? 548 ARG B NH2 1 ATOM 9828 N N . VAL B 1 529 ? -22.334 -34.281 72.430 1.00 25.24 ? 549 VAL B N 1 ATOM 9829 C CA . VAL B 1 529 ? -22.269 -33.008 71.730 1.00 24.45 ? 549 VAL B CA 1 ATOM 9830 C C . VAL B 1 529 ? -21.794 -33.297 70.307 1.00 24.31 ? 549 VAL B C 1 ATOM 9831 O O . VAL B 1 529 ? -20.691 -33.805 70.107 1.00 23.55 ? 549 VAL B O 1 ATOM 9832 C CB . VAL B 1 529 ? -21.333 -32.005 72.445 1.00 24.43 ? 549 VAL B CB 1 ATOM 9833 C CG1 . VAL B 1 529 ? -21.064 -30.792 71.564 1.00 24.01 ? 549 VAL B CG1 1 ATOM 9834 C CG2 . VAL B 1 529 ? -21.938 -31.578 73.780 1.00 23.79 ? 549 VAL B CG2 1 ATOM 9835 N N . VAL B 1 530 ? -22.655 -33.013 69.330 1.00 24.25 ? 550 VAL B N 1 ATOM 9836 C CA . VAL B 1 530 ? -22.291 -33.090 67.913 1.00 24.38 ? 550 VAL B CA 1 ATOM 9837 C C . VAL B 1 530 ? -22.207 -31.655 67.399 1.00 24.52 ? 550 VAL B C 1 ATOM 9838 O O . VAL B 1 530 ? -23.228 -30.976 67.293 1.00 24.59 ? 550 VAL B O 1 ATOM 9839 C CB . VAL B 1 530 ? -23.310 -33.937 67.109 1.00 24.35 ? 550 VAL B CB 1 ATOM 9840 C CG1 . VAL B 1 530 ? -23.011 -33.898 65.616 1.00 24.80 ? 550 VAL B CG1 1 ATOM 9841 C CG2 . VAL B 1 530 ? -23.304 -35.382 67.620 1.00 23.37 ? 550 VAL B CG2 1 ATOM 9842 N N . GLN B 1 531 ? -20.990 -31.194 67.117 1.00 24.60 ? 551 GLN B N 1 ATOM 9843 C CA . GLN B 1 531 ? -20.729 -29.768 66.923 1.00 24.70 ? 551 GLN B CA 1 ATOM 9844 C C . GLN B 1 531 ? -19.623 -29.471 65.909 1.00 24.94 ? 551 GLN B C 1 ATOM 9845 O O . GLN B 1 531 ? -18.791 -30.337 65.620 1.00 24.89 ? 551 GLN B O 1 ATOM 9846 C CB . GLN B 1 531 ? -20.341 -29.120 68.252 1.00 24.69 ? 551 GLN B CB 1 ATOM 9847 C CG . GLN B 1 531 ? -18.929 -29.480 68.765 1.00 25.36 ? 551 GLN B CG 1 ATOM 9848 C CD . GLN B 1 531 ? -18.410 -28.503 69.810 1.00 25.29 ? 551 GLN B CD 1 ATOM 9849 O OE1 . GLN B 1 531 ? -18.949 -27.421 69.960 1.00 26.18 ? 551 GLN B OE1 1 ATOM 9850 N NE2 . GLN B 1 531 ? -17.340 -28.874 70.513 1.00 25.96 ? 551 GLN B NE2 1 ATOM 9851 N N . PRO B 1 532 ? -19.604 -28.229 65.385 1.00 25.05 ? 552 PRO B N 1 ATOM 9852 C CA . PRO B 1 532 ? -18.576 -27.777 64.459 1.00 25.26 ? 552 PRO B CA 1 ATOM 9853 C C . PRO B 1 532 ? -17.178 -27.745 65.047 1.00 25.61 ? 552 PRO B C 1 ATOM 9854 O O . PRO B 1 532 ? -17.004 -27.363 66.207 1.00 25.41 ? 552 PRO B O 1 ATOM 9855 C CB . PRO B 1 532 ? -19.001 -26.346 64.134 1.00 25.15 ? 552 PRO B CB 1 ATOM 9856 C CG . PRO B 1 532 ? -20.457 -26.322 64.347 1.00 25.48 ? 552 PRO B CG 1 ATOM 9857 C CD . PRO B 1 532 ? -20.716 -27.269 65.474 1.00 24.90 ? 552 PRO B CD 1 ATOM 9858 N N . THR B 1 533 ? -16.204 -28.148 64.234 1.00 25.83 ? 553 THR B N 1 ATOM 9859 C CA . THR B 1 533 ? -14.797 -27.863 64.477 1.00 26.18 ? 553 THR B CA 1 ATOM 9860 C C . THR B 1 533 ? -14.210 -27.236 63.223 1.00 27.10 ? 553 THR B C 1 ATOM 9861 O O . THR B 1 533 ? -14.769 -27.344 62.133 1.00 26.71 ? 553 THR B O 1 ATOM 9862 C CB . THR B 1 533 ? -13.986 -29.118 64.777 1.00 26.30 ? 553 THR B CB 1 ATOM 9863 O OG1 . THR B 1 533 ? -13.927 -29.934 63.600 1.00 25.49 ? 553 THR B OG1 1 ATOM 9864 C CG2 . THR B 1 533 ? -14.592 -29.915 65.938 1.00 25.89 ? 553 THR B CG2 1 ATOM 9865 N N . LEU B 1 534 ? -13.058 -26.602 63.392 1.00 28.30 ? 554 LEU B N 1 ATOM 9866 C CA . LEU B 1 534 ? -12.386 -25.879 62.330 1.00 29.17 ? 554 LEU B CA 1 ATOM 9867 C C . LEU B 1 534 ? -11.288 -26.758 61.773 1.00 29.98 ? 554 LEU B C 1 ATOM 9868 O O . LEU B 1 534 ? -10.379 -27.128 62.503 1.00 30.41 ? 554 LEU B O 1 ATOM 9869 C CB . LEU B 1 534 ? -11.803 -24.583 62.897 1.00 29.44 ? 554 LEU B CB 1 ATOM 9870 C CG . LEU B 1 534 ? -10.882 -23.691 62.058 1.00 30.32 ? 554 LEU B CG 1 ATOM 9871 C CD1 . LEU B 1 534 ? -11.324 -23.593 60.619 1.00 30.84 ? 554 LEU B CD1 1 ATOM 9872 C CD2 . LEU B 1 534 ? -10.824 -22.310 62.711 1.00 31.34 ? 554 LEU B CD2 1 ATOM 9873 N N . GLU B 1 535 ? -11.373 -27.086 60.482 1.00 30.76 ? 555 GLU B N 1 ATOM 9874 C CA . GLU B 1 535 ? -10.403 -27.964 59.822 1.00 31.10 ? 555 GLU B CA 1 ATOM 9875 C C . GLU B 1 535 ? -9.586 -27.175 58.809 1.00 30.85 ? 555 GLU B C 1 ATOM 9876 O O . GLU B 1 535 ? -10.152 -26.443 57.996 1.00 30.91 ? 555 GLU B O 1 ATOM 9877 C CB . GLU B 1 535 ? -11.151 -29.099 59.130 1.00 31.77 ? 555 GLU B CB 1 ATOM 9878 C CG . GLU B 1 535 ? -10.296 -30.085 58.347 1.00 33.59 ? 555 GLU B CG 1 ATOM 9879 C CD . GLU B 1 535 ? -11.141 -31.012 57.485 1.00 35.42 ? 555 GLU B CD 1 ATOM 9880 O OE1 . GLU B 1 535 ? -11.520 -30.609 56.362 1.00 36.37 ? 555 GLU B OE1 1 ATOM 9881 O OE2 . GLU B 1 535 ? -11.425 -32.144 57.935 1.00 38.55 ? 555 GLU B OE2 1 ATOM 9882 N N . GLN B 1 536 ? -8.263 -27.331 58.866 1.00 30.21 ? 556 GLN B N 1 ATOM 9883 C CA . GLN B 1 536 ? -7.342 -26.628 57.977 1.00 30.25 ? 556 GLN B CA 1 ATOM 9884 C C . GLN B 1 536 ? -6.663 -27.629 57.057 1.00 30.32 ? 556 GLN B C 1 ATOM 9885 O O . GLN B 1 536 ? -6.217 -28.682 57.507 1.00 30.98 ? 556 GLN B O 1 ATOM 9886 C CB . GLN B 1 536 ? -6.291 -25.859 58.779 1.00 30.01 ? 556 GLN B CB 1 ATOM 9887 N N . THR B 1 537 ? -6.607 -27.313 55.768 1.00 30.06 ? 557 THR B N 1 ATOM 9888 C CA . THR B 1 537 ? -5.949 -28.164 54.781 1.00 29.87 ? 557 THR B CA 1 ATOM 9889 C C . THR B 1 537 ? -4.828 -27.386 54.129 1.00 29.89 ? 557 THR B C 1 ATOM 9890 O O . THR B 1 537 ? -5.047 -26.284 53.652 1.00 29.43 ? 557 THR B O 1 ATOM 9891 C CB . THR B 1 537 ? -6.927 -28.601 53.690 1.00 29.72 ? 557 THR B CB 1 ATOM 9892 O OG1 . THR B 1 537 ? -8.019 -29.305 54.288 1.00 30.01 ? 557 THR B OG1 1 ATOM 9893 C CG2 . THR B 1 537 ? -6.240 -29.489 52.659 1.00 29.40 ? 557 THR B CG2 1 ATOM 9894 N N . GLN B 1 538 ? -3.625 -27.954 54.131 1.00 30.27 ? 558 GLN B N 1 ATOM 9895 C CA . GLN B 1 538 ? -2.490 -27.362 53.423 1.00 30.67 ? 558 GLN B CA 1 ATOM 9896 C C . GLN B 1 538 ? -2.384 -27.961 52.023 1.00 30.12 ? 558 GLN B C 1 ATOM 9897 O O . GLN B 1 538 ? -2.934 -29.022 51.748 1.00 30.49 ? 558 GLN B O 1 ATOM 9898 C CB . GLN B 1 538 ? -1.189 -27.587 54.192 1.00 31.04 ? 558 GLN B CB 1 ATOM 9899 C CG . GLN B 1 538 ? -1.204 -27.063 55.635 1.00 33.07 ? 558 GLN B CG 1 ATOM 9900 C CD . GLN B 1 538 ? -1.624 -25.600 55.747 1.00 35.07 ? 558 GLN B CD 1 ATOM 9901 O OE1 . GLN B 1 538 ? -1.076 -24.731 55.069 1.00 36.88 ? 558 GLN B OE1 1 ATOM 9902 N NE2 . GLN B 1 538 ? -2.604 -25.327 56.610 1.00 36.56 ? 558 GLN B NE2 1 ATOM 9903 N N . TYR B 1 539 ? -1.695 -27.255 51.139 1.00 29.83 ? 559 TYR B N 1 ATOM 9904 C CA . TYR B 1 539 ? -1.504 -27.681 49.749 1.00 29.50 ? 559 TYR B CA 1 ATOM 9905 C C . TYR B 1 539 ? -0.033 -27.497 49.387 1.00 29.52 ? 559 TYR B C 1 ATOM 9906 O O . TYR B 1 539 ? 0.518 -26.409 49.541 1.00 29.49 ? 559 TYR B O 1 ATOM 9907 C CB . TYR B 1 539 ? -2.379 -26.845 48.809 1.00 29.21 ? 559 TYR B CB 1 ATOM 9908 C CG . TYR B 1 539 ? -3.864 -27.006 49.056 1.00 28.65 ? 559 TYR B CG 1 ATOM 9909 C CD1 . TYR B 1 539 ? -4.481 -26.409 50.158 1.00 27.80 ? 559 TYR B CD1 1 ATOM 9910 C CD2 . TYR B 1 539 ? -4.652 -27.760 48.194 1.00 28.13 ? 559 TYR B CD2 1 ATOM 9911 C CE1 . TYR B 1 539 ? -5.834 -26.572 50.397 1.00 28.10 ? 559 TYR B CE1 1 ATOM 9912 C CE2 . TYR B 1 539 ? -6.004 -27.919 48.421 1.00 28.20 ? 559 TYR B CE2 1 ATOM 9913 C CZ . TYR B 1 539 ? -6.591 -27.324 49.522 1.00 27.54 ? 559 TYR B CZ 1 ATOM 9914 O OH . TYR B 1 539 ? -7.934 -27.478 49.737 1.00 28.33 ? 559 TYR B OH 1 ATOM 9915 N N . SER B 1 540 ? 0.593 -28.565 48.908 1.00 29.61 ? 560 SER B N 1 ATOM 9916 C CA . SER B 1 540 ? 2.022 -28.556 48.616 1.00 29.81 ? 560 SER B CA 1 ATOM 9917 C C . SER B 1 540 ? 2.361 -28.464 47.129 1.00 29.82 ? 560 SER B C 1 ATOM 9918 O O . SER B 1 540 ? 3.430 -27.954 46.771 1.00 30.05 ? 560 SER B O 1 ATOM 9919 C CB . SER B 1 540 ? 2.667 -29.808 49.203 1.00 29.96 ? 560 SER B CB 1 ATOM 9920 O OG . SER B 1 540 ? 2.791 -29.683 50.605 1.00 30.46 ? 560 SER B OG 1 ATOM 9921 N N . TRP B 1 541 ? 1.465 -28.963 46.278 1.00 29.43 ? 561 TRP B N 1 ATOM 9922 C CA . TRP B 1 541 ? 1.744 -29.116 44.851 1.00 29.58 ? 561 TRP B CA 1 ATOM 9923 C C . TRP B 1 541 ? 0.638 -28.501 44.001 1.00 29.09 ? 561 TRP B C 1 ATOM 9924 O O . TRP B 1 541 ? -0.548 -28.638 44.319 1.00 29.51 ? 561 TRP B O 1 ATOM 9925 C CB . TRP B 1 541 ? 1.895 -30.604 44.511 1.00 29.66 ? 561 TRP B CB 1 ATOM 9926 C CG . TRP B 1 541 ? 2.869 -31.311 45.395 1.00 31.21 ? 561 TRP B CG 1 ATOM 9927 C CD1 . TRP B 1 541 ? 2.576 -32.140 46.445 1.00 32.67 ? 561 TRP B CD1 1 ATOM 9928 C CD2 . TRP B 1 541 ? 4.297 -31.243 45.325 1.00 32.32 ? 561 TRP B CD2 1 ATOM 9929 N NE1 . TRP B 1 541 ? 3.732 -32.596 47.022 1.00 32.85 ? 561 TRP B NE1 1 ATOM 9930 C CE2 . TRP B 1 541 ? 4.804 -32.060 46.356 1.00 33.69 ? 561 TRP B CE2 1 ATOM 9931 C CE3 . TRP B 1 541 ? 5.198 -30.589 44.477 1.00 33.40 ? 561 TRP B CE3 1 ATOM 9932 C CZ2 . TRP B 1 541 ? 6.176 -32.229 46.570 1.00 33.62 ? 561 TRP B CZ2 1 ATOM 9933 C CZ3 . TRP B 1 541 ? 6.562 -30.752 44.692 1.00 33.26 ? 561 TRP B CZ3 1 ATOM 9934 C CH2 . TRP B 1 541 ? 7.036 -31.565 45.729 1.00 33.86 ? 561 TRP B CH2 1 ATOM 9935 N N . GLU B 1 542 ? 1.028 -27.838 42.914 1.00 28.69 ? 562 GLU B N 1 ATOM 9936 C CA . GLU B 1 542 ? 0.076 -27.150 42.030 1.00 28.30 ? 562 GLU B CA 1 ATOM 9937 C C . GLU B 1 542 ? -1.221 -27.936 41.790 1.00 28.10 ? 562 GLU B C 1 ATOM 9938 O O . GLU B 1 542 ? -2.319 -27.397 41.973 1.00 28.18 ? 562 GLU B O 1 ATOM 9939 C CB . GLU B 1 542 ? 0.736 -26.826 40.690 1.00 28.23 ? 562 GLU B CB 1 ATOM 9940 C CG . GLU B 1 542 ? 1.686 -25.649 40.752 1.00 27.91 ? 562 GLU B CG 1 ATOM 9941 C CD . GLU B 1 542 ? 2.359 -25.368 39.427 1.00 27.67 ? 562 GLU B CD 1 ATOM 9942 O OE1 . GLU B 1 542 ? 2.674 -26.336 38.705 1.00 27.24 ? 562 GLU B OE1 1 ATOM 9943 O OE2 . GLU B 1 542 ? 2.590 -24.181 39.101 1.00 26.67 ? 562 GLU B OE2 1 ATOM 9944 N N . ARG B 1 543 ? -1.080 -29.207 41.415 1.00 27.78 ? 563 ARG B N 1 ATOM 9945 C CA . ARG B 1 543 ? -2.221 -30.067 41.060 1.00 27.57 ? 563 ARG B CA 1 ATOM 9946 C C . ARG B 1 543 ? -3.262 -30.214 42.176 1.00 27.32 ? 563 ARG B C 1 ATOM 9947 O O . ARG B 1 543 ? -4.467 -30.329 41.897 1.00 27.30 ? 563 ARG B O 1 ATOM 9948 C CB . ARG B 1 543 ? -1.729 -31.446 40.616 1.00 27.71 ? 563 ARG B CB 1 ATOM 9949 C CG . ARG B 1 543 ? -2.827 -32.469 40.270 1.00 28.25 ? 563 ARG B CG 1 ATOM 9950 C CD . ARG B 1 543 ? -3.860 -31.968 39.248 1.00 29.18 ? 563 ARG B CD 1 ATOM 9951 N NE . ARG B 1 543 ? -3.287 -31.651 37.940 1.00 28.81 ? 563 ARG B NE 1 ATOM 9952 C CZ . ARG B 1 543 ? -3.957 -31.092 36.931 1.00 28.59 ? 563 ARG B CZ 1 ATOM 9953 N NH1 . ARG B 1 543 ? -5.245 -30.766 37.055 1.00 28.33 ? 563 ARG B NH1 1 ATOM 9954 N NH2 . ARG B 1 543 ? -3.335 -30.860 35.776 1.00 28.27 ? 563 ARG B NH2 1 ATOM 9955 N N . GLN B 1 544 ? -2.803 -30.214 43.427 1.00 26.61 ? 564 GLN B N 1 ATOM 9956 C CA . GLN B 1 544 ? -3.708 -30.275 44.585 1.00 26.05 ? 564 GLN B CA 1 ATOM 9957 C C . GLN B 1 544 ? -4.609 -29.036 44.674 1.00 25.23 ? 564 GLN B C 1 ATOM 9958 O O . GLN B 1 544 ? -5.705 -29.107 45.206 1.00 25.49 ? 564 GLN B O 1 ATOM 9959 C CB . GLN B 1 544 ? -2.900 -30.376 45.887 1.00 26.09 ? 564 GLN B CB 1 ATOM 9960 C CG . GLN B 1 544 ? -2.039 -31.639 46.027 1.00 25.81 ? 564 GLN B CG 1 ATOM 9961 C CD . GLN B 1 544 ? -1.170 -31.616 47.281 1.00 26.30 ? 564 GLN B CD 1 ATOM 9962 O OE1 . GLN B 1 544 ? -0.476 -30.633 47.556 1.00 25.45 ? 564 GLN B OE1 1 ATOM 9963 N NE2 . GLN B 1 544 ? -1.210 -32.701 48.046 1.00 25.76 ? 564 GLN B NE2 1 ATOM 9964 N N . ALA B 1 545 ? -4.118 -27.907 44.171 1.00 24.85 ? 565 ALA B N 1 ATOM 9965 C CA . ALA B 1 545 ? -4.826 -26.624 44.209 1.00 24.34 ? 565 ALA B CA 1 ATOM 9966 C C . ALA B 1 545 ? -5.523 -26.272 42.878 1.00 24.02 ? 565 ALA B C 1 ATOM 9967 O O . ALA B 1 545 ? -5.883 -25.111 42.657 1.00 23.69 ? 565 ALA B O 1 ATOM 9968 C CB . ALA B 1 545 ? -3.855 -25.531 44.586 1.00 24.23 ? 565 ALA B CB 1 ATOM 9969 N N . ALA B 1 546 ? -5.685 -27.261 41.998 1.00 23.54 ? 566 ALA B N 1 ATOM 9970 C CA . ALA B 1 546 ? -6.426 -27.092 40.749 1.00 23.62 ? 566 ALA B CA 1 ATOM 9971 C C . ALA B 1 546 ? -7.801 -27.695 40.949 1.00 23.70 ? 566 ALA B C 1 ATOM 9972 O O . ALA B 1 546 ? -7.965 -28.905 40.855 1.00 24.09 ? 566 ALA B O 1 ATOM 9973 C CB . ALA B 1 546 ? -5.712 -27.785 39.608 1.00 23.24 ? 566 ALA B CB 1 ATOM 9974 N N . PHE B 1 547 ? -8.780 -26.855 41.250 1.00 24.18 ? 567 PHE B N 1 ATOM 9975 C CA . PHE B 1 547 ? -10.128 -27.320 41.569 1.00 24.68 ? 567 PHE B CA 1 ATOM 9976 C C . PHE B 1 547 ? -10.954 -27.373 40.301 1.00 25.72 ? 567 PHE B C 1 ATOM 9977 O O . PHE B 1 547 ? -11.140 -26.352 39.647 1.00 25.58 ? 567 PHE B O 1 ATOM 9978 C CB . PHE B 1 547 ? -10.792 -26.378 42.575 1.00 24.45 ? 567 PHE B CB 1 ATOM 9979 C CG . PHE B 1 547 ? -10.089 -26.316 43.896 1.00 23.29 ? 567 PHE B CG 1 ATOM 9980 C CD1 . PHE B 1 547 ? -9.004 -25.476 44.078 1.00 22.21 ? 567 PHE B CD1 1 ATOM 9981 C CD2 . PHE B 1 547 ? -10.495 -27.123 44.954 1.00 23.16 ? 567 PHE B CD2 1 ATOM 9982 C CE1 . PHE B 1 547 ? -8.340 -25.421 45.296 1.00 22.75 ? 567 PHE B CE1 1 ATOM 9983 C CE2 . PHE B 1 547 ? -9.839 -27.072 46.182 1.00 22.34 ? 567 PHE B CE2 1 ATOM 9984 C CZ . PHE B 1 547 ? -8.757 -26.225 46.348 1.00 22.64 ? 567 PHE B CZ 1 ATOM 9985 N N . ARG B 1 548 ? -11.420 -28.563 39.941 1.00 27.22 ? 568 ARG B N 1 ATOM 9986 C CA . ARG B 1 548 ? -12.353 -28.723 38.829 1.00 28.75 ? 568 ARG B CA 1 ATOM 9987 C C . ARG B 1 548 ? -13.759 -28.438 39.325 1.00 29.71 ? 568 ARG B C 1 ATOM 9988 O O . ARG B 1 548 ? -14.013 -28.447 40.528 1.00 29.96 ? 568 ARG B O 1 ATOM 9989 C CB . ARG B 1 548 ? -12.292 -30.138 38.251 1.00 29.18 ? 568 ARG B CB 1 ATOM 9990 C CG . ARG B 1 548 ? -10.976 -30.467 37.555 1.00 30.84 ? 568 ARG B CG 1 ATOM 9991 C CD . ARG B 1 548 ? -10.821 -31.955 37.326 1.00 32.96 ? 568 ARG B CD 1 ATOM 9992 N NE . ARG B 1 548 ? -9.589 -32.252 36.598 1.00 35.66 ? 568 ARG B NE 1 ATOM 9993 N N . PHE B 1 549 ? -14.669 -28.184 38.393 1.00 30.99 ? 569 PHE B N 1 ATOM 9994 C CA . PHE B 1 549 ? -16.068 -27.938 38.733 1.00 31.96 ? 569 PHE B CA 1 ATOM 9995 C C . PHE B 1 549 ? -16.725 -29.163 39.367 1.00 33.14 ? 569 PHE B C 1 ATOM 9996 O O . PHE B 1 549 ? -17.698 -29.024 40.095 1.00 33.90 ? 569 PHE B O 1 ATOM 9997 C CB . PHE B 1 549 ? -16.860 -27.484 37.499 1.00 31.72 ? 569 PHE B CB 1 ATOM 9998 C CG . PHE B 1 549 ? -16.570 -26.068 37.086 1.00 31.00 ? 569 PHE B CG 1 ATOM 9999 C CD1 . PHE B 1 549 ? -17.063 -25.006 37.833 1.00 30.39 ? 569 PHE B CD1 1 ATOM 10000 C CD2 . PHE B 1 549 ? -15.802 -25.791 35.959 1.00 30.12 ? 569 PHE B CD2 1 ATOM 10001 C CE1 . PHE B 1 549 ? -16.794 -23.690 37.461 1.00 30.56 ? 569 PHE B CE1 1 ATOM 10002 C CE2 . PHE B 1 549 ? -15.534 -24.475 35.584 1.00 29.82 ? 569 PHE B CE2 1 ATOM 10003 C CZ . PHE B 1 549 ? -16.026 -23.428 36.337 1.00 30.22 ? 569 PHE B CZ 1 ATOM 10004 N N . LYS B 1 550 ? -16.209 -30.354 39.079 1.00 34.22 ? 570 LYS B N 1 ATOM 10005 C CA . LYS B 1 550 ? -16.670 -31.575 39.746 1.00 35.03 ? 570 LYS B CA 1 ATOM 10006 C C . LYS B 1 550 ? -16.362 -31.523 41.242 1.00 36.00 ? 570 LYS B C 1 ATOM 10007 O O . LYS B 1 550 ? -17.211 -31.838 42.060 1.00 36.50 ? 570 LYS B O 1 ATOM 10008 C CB . LYS B 1 550 ? -15.993 -32.804 39.137 1.00 34.90 ? 570 LYS B CB 1 ATOM 10009 N N . ARG B 1 551 ? -15.142 -31.107 41.579 1.00 37.04 ? 571 ARG B N 1 ATOM 10010 C CA . ARG B 1 551 ? -14.662 -31.047 42.971 1.00 37.66 ? 571 ARG B CA 1 ATOM 10011 C C . ARG B 1 551 ? -15.466 -30.024 43.804 1.00 37.67 ? 571 ARG B C 1 ATOM 10012 O O . ARG B 1 551 ? -15.905 -28.984 43.288 1.00 38.03 ? 571 ARG B O 1 ATOM 10013 C CB . ARG B 1 551 ? -13.161 -30.689 42.966 1.00 38.18 ? 571 ARG B CB 1 ATOM 10014 C CG . ARG B 1 551 ? -12.340 -31.133 44.190 1.00 39.66 ? 571 ARG B CG 1 ATOM 10015 C CD . ARG B 1 551 ? -10.843 -31.000 43.887 1.00 41.20 ? 571 ARG B CD 1 ATOM 10016 N NE . ARG B 1 551 ? -10.006 -30.916 45.082 1.00 42.51 ? 571 ARG B NE 1 ATOM 10017 C CZ . ARG B 1 551 ? -8.724 -30.544 45.094 1.00 43.08 ? 571 ARG B CZ 1 ATOM 10018 N NH1 . ARG B 1 551 ? -8.093 -30.205 43.971 1.00 43.85 ? 571 ARG B NH1 1 ATOM 10019 N NH2 . ARG B 1 551 ? -8.063 -30.501 46.246 1.00 43.29 ? 571 ARG B NH2 1 ATOM 10020 N N . LYS B 1 552 ? -15.674 -30.332 45.083 1.00 37.18 ? 572 LYS B N 1 ATOM 10021 C CA . LYS B 1 552 ? -16.342 -29.406 46.010 1.00 36.40 ? 572 LYS B CA 1 ATOM 10022 C C . LYS B 1 552 ? -15.369 -28.283 46.362 1.00 35.27 ? 572 LYS B C 1 ATOM 10023 O O . LYS B 1 552 ? -14.241 -28.551 46.778 1.00 35.85 ? 572 LYS B O 1 ATOM 10024 C CB . LYS B 1 552 ? -16.783 -30.145 47.283 1.00 36.53 ? 572 LYS B CB 1 ATOM 10025 N N . LEU B 1 553 ? -15.785 -27.035 46.163 1.00 33.70 ? 573 LEU B N 1 ATOM 10026 C CA . LEU B 1 553 ? -14.911 -25.888 46.430 1.00 32.60 ? 573 LEU B CA 1 ATOM 10027 C C . LEU B 1 553 ? -15.003 -25.532 47.910 1.00 31.18 ? 573 LEU B C 1 ATOM 10028 O O . LEU B 1 553 ? -16.092 -25.264 48.397 1.00 30.42 ? 573 LEU B O 1 ATOM 10029 C CB . LEU B 1 553 ? -15.317 -24.688 45.565 1.00 32.67 ? 573 LEU B CB 1 ATOM 10030 C CG . LEU B 1 553 ? -14.269 -23.616 45.236 1.00 33.03 ? 573 LEU B CG 1 ATOM 10031 C CD1 . LEU B 1 553 ? -12.974 -24.202 44.634 1.00 32.28 ? 573 LEU B CD1 1 ATOM 10032 C CD2 . LEU B 1 553 ? -14.881 -22.610 44.266 1.00 31.25 ? 573 LEU B CD2 1 ATOM 10033 N N . PRO B 1 554 ? -13.866 -25.543 48.635 1.00 29.86 ? 574 PRO B N 1 ATOM 10034 C CA . PRO B 1 554 ? -13.913 -25.151 50.044 1.00 29.25 ? 574 PRO B CA 1 ATOM 10035 C C . PRO B 1 554 ? -14.463 -23.734 50.259 1.00 28.66 ? 574 PRO B C 1 ATOM 10036 O O . PRO B 1 554 ? -14.320 -22.865 49.395 1.00 28.00 ? 574 PRO B O 1 ATOM 10037 C CB . PRO B 1 554 ? -12.443 -25.217 50.485 1.00 29.38 ? 574 PRO B CB 1 ATOM 10038 C CG . PRO B 1 554 ? -11.781 -26.105 49.505 1.00 29.82 ? 574 PRO B CG 1 ATOM 10039 C CD . PRO B 1 554 ? -12.503 -25.908 48.211 1.00 29.71 ? 574 PRO B CD 1 ATOM 10040 N N . LYS B 1 555 ? -15.074 -23.510 51.415 1.00 27.96 ? 575 LYS B N 1 ATOM 10041 C CA . LYS B 1 555 ? -15.691 -22.226 51.713 1.00 27.66 ? 575 LYS B CA 1 ATOM 10042 C C . LYS B 1 555 ? -14.656 -21.142 52.004 1.00 26.82 ? 575 LYS B C 1 ATOM 10043 O O . LYS B 1 555 ? -14.924 -19.971 51.748 1.00 27.05 ? 575 LYS B O 1 ATOM 10044 C CB . LYS B 1 555 ? -16.678 -22.361 52.880 1.00 27.97 ? 575 LYS B CB 1 ATOM 10045 C CG . LYS B 1 555 ? -17.791 -23.372 52.633 1.00 29.36 ? 575 LYS B CG 1 ATOM 10046 C CD . LYS B 1 555 ? -18.655 -22.985 51.447 1.00 31.13 ? 575 LYS B CD 1 ATOM 10047 C CE . LYS B 1 555 ? -19.663 -24.083 51.096 1.00 32.95 ? 575 LYS B CE 1 ATOM 10048 N NZ . LYS B 1 555 ? -20.150 -23.906 49.701 1.00 32.44 ? 575 LYS B NZ 1 ATOM 10049 N N . TYR B 1 556 ? -13.484 -21.523 52.520 1.00 25.42 ? 576 TYR B N 1 ATOM 10050 C CA . TYR B 1 556 ? -12.387 -20.569 52.743 1.00 24.52 ? 576 TYR B CA 1 ATOM 10051 C C . TYR B 1 556 ? -11.179 -20.901 51.874 1.00 24.06 ? 576 TYR B C 1 ATOM 10052 O O . TYR B 1 556 ? -10.540 -21.929 52.057 1.00 23.40 ? 576 TYR B O 1 ATOM 10053 C CB . TYR B 1 556 ? -11.997 -20.505 54.229 1.00 24.34 ? 576 TYR B CB 1 ATOM 10054 C CG . TYR B 1 556 ? -12.958 -19.650 55.024 1.00 23.49 ? 576 TYR B CG 1 ATOM 10055 C CD1 . TYR B 1 556 ? -14.264 -20.071 55.245 1.00 23.28 ? 576 TYR B CD1 1 ATOM 10056 C CD2 . TYR B 1 556 ? -12.579 -18.405 55.512 1.00 22.86 ? 576 TYR B CD2 1 ATOM 10057 C CE1 . TYR B 1 556 ? -15.165 -19.278 55.952 1.00 23.89 ? 576 TYR B CE1 1 ATOM 10058 C CE2 . TYR B 1 556 ? -13.468 -17.608 56.216 1.00 22.99 ? 576 TYR B CE2 1 ATOM 10059 C CZ . TYR B 1 556 ? -14.761 -18.048 56.430 1.00 23.75 ? 576 TYR B CZ 1 ATOM 10060 O OH . TYR B 1 556 ? -15.649 -17.266 57.128 1.00 23.28 ? 576 TYR B OH 1 ATOM 10061 N N . LEU B 1 557 ? -10.891 -20.016 50.923 1.00 23.39 ? 577 LEU B N 1 ATOM 10062 C CA . LEU B 1 557 ? -9.753 -20.151 50.034 1.00 23.26 ? 577 LEU B CA 1 ATOM 10063 C C . LEU B 1 557 ? -8.729 -19.070 50.406 1.00 23.40 ? 577 LEU B C 1 ATOM 10064 O O . LEU B 1 557 ? -8.929 -17.895 50.122 1.00 23.35 ? 577 LEU B O 1 ATOM 10065 C CB . LEU B 1 557 ? -10.219 -20.015 48.590 1.00 22.79 ? 577 LEU B CB 1 ATOM 10066 C CG . LEU B 1 557 ? -11.311 -20.999 48.143 1.00 22.45 ? 577 LEU B CG 1 ATOM 10067 C CD1 . LEU B 1 557 ? -12.031 -20.481 46.896 1.00 20.95 ? 577 LEU B CD1 1 ATOM 10068 C CD2 . LEU B 1 557 ? -10.730 -22.384 47.892 1.00 21.03 ? 577 LEU B CD2 1 ATOM 10069 N N . LEU B 1 558 ? -7.651 -19.471 51.074 1.00 23.78 ? 578 LEU B N 1 ATOM 10070 C CA . LEU B 1 558 ? -6.746 -18.514 51.711 1.00 23.97 ? 578 LEU B CA 1 ATOM 10071 C C . LEU B 1 558 ? -5.352 -18.513 51.089 1.00 24.36 ? 578 LEU B C 1 ATOM 10072 O O . LEU B 1 558 ? -4.747 -19.565 50.867 1.00 24.23 ? 578 LEU B O 1 ATOM 10073 C CB . LEU B 1 558 ? -6.611 -18.817 53.200 1.00 24.28 ? 578 LEU B CB 1 ATOM 10074 C CG . LEU B 1 558 ? -7.845 -18.689 54.103 1.00 24.69 ? 578 LEU B CG 1 ATOM 10075 C CD1 . LEU B 1 558 ? -7.398 -18.946 55.537 1.00 24.43 ? 578 LEU B CD1 1 ATOM 10076 C CD2 . LEU B 1 558 ? -8.515 -17.335 53.986 1.00 23.51 ? 578 LEU B CD2 1 ATOM 10077 N N . PHE B 1 559 ? -4.857 -17.310 50.821 1.00 24.84 ? 579 PHE B N 1 ATOM 10078 C CA . PHE B 1 559 ? -3.472 -17.092 50.437 1.00 25.01 ? 579 PHE B CA 1 ATOM 10079 C C . PHE B 1 559 ? -2.794 -16.405 51.617 1.00 25.78 ? 579 PHE B C 1 ATOM 10080 O O . PHE B 1 559 ? -3.199 -15.324 52.036 1.00 25.54 ? 579 PHE B O 1 ATOM 10081 C CB . PHE B 1 559 ? -3.419 -16.292 49.142 1.00 24.66 ? 579 PHE B CB 1 ATOM 10082 C CG . PHE B 1 559 ? -4.084 -17.004 48.004 1.00 23.48 ? 579 PHE B CG 1 ATOM 10083 C CD1 . PHE B 1 559 ? -5.464 -16.986 47.875 1.00 21.80 ? 579 PHE B CD1 1 ATOM 10084 C CD2 . PHE B 1 559 ? -3.348 -17.766 47.120 1.00 22.46 ? 579 PHE B CD2 1 ATOM 10085 C CE1 . PHE B 1 559 ? -6.096 -17.678 46.845 1.00 21.87 ? 579 PHE B CE1 1 ATOM 10086 C CE2 . PHE B 1 559 ? -3.973 -18.461 46.080 1.00 21.99 ? 579 PHE B CE2 1 ATOM 10087 C CZ . PHE B 1 559 ? -5.350 -18.419 45.951 1.00 21.06 ? 579 PHE B CZ 1 ATOM 10088 N N . THR B 1 560 ? -1.787 -17.073 52.169 1.00 26.61 ? 580 THR B N 1 ATOM 10089 C CA . THR B 1 560 ? -1.276 -16.751 53.493 1.00 27.72 ? 580 THR B CA 1 ATOM 10090 C C . THR B 1 560 ? 0.183 -16.338 53.451 1.00 28.28 ? 580 THR B C 1 ATOM 10091 O O . THR B 1 560 ? 0.957 -16.858 52.650 1.00 28.43 ? 580 THR B O 1 ATOM 10092 C CB . THR B 1 560 ? -1.357 -17.971 54.405 1.00 27.73 ? 580 THR B CB 1 ATOM 10093 O OG1 . THR B 1 560 ? -0.415 -18.949 53.943 1.00 29.62 ? 580 THR B OG1 1 ATOM 10094 C CG2 . THR B 1 560 ? -2.760 -18.569 54.395 1.00 26.44 ? 580 THR B CG2 1 ATOM 10095 N N . SER B 1 561 ? 0.540 -15.404 54.324 1.00 29.21 ? 581 SER B N 1 ATOM 10096 C CA . SER B 1 561 ? 1.925 -15.055 54.586 1.00 29.99 ? 581 SER B CA 1 ATOM 10097 C C . SER B 1 561 ? 2.381 -15.835 55.817 1.00 30.80 ? 581 SER B C 1 ATOM 10098 O O . SER B 1 561 ? 1.558 -16.147 56.686 1.00 31.08 ? 581 SER B O 1 ATOM 10099 C CB . SER B 1 561 ? 2.044 -13.549 54.852 1.00 30.48 ? 581 SER B CB 1 ATOM 10100 O OG . SER B 1 561 ? 3.372 -13.163 55.174 1.00 30.21 ? 581 SER B OG 1 ATOM 10101 N N . PRO B 1 562 ? 3.690 -16.150 55.908 1.00 31.55 ? 582 PRO B N 1 ATOM 10102 C CA . PRO B 1 562 ? 4.239 -16.730 57.143 1.00 31.82 ? 582 PRO B CA 1 ATOM 10103 C C . PRO B 1 562 ? 4.162 -15.787 58.341 1.00 31.97 ? 582 PRO B C 1 ATOM 10104 O O . PRO B 1 562 ? 4.196 -16.245 59.479 1.00 32.21 ? 582 PRO B O 1 ATOM 10105 C CB . PRO B 1 562 ? 5.713 -16.989 56.799 1.00 32.10 ? 582 PRO B CB 1 ATOM 10106 C CG . PRO B 1 562 ? 5.818 -16.882 55.330 1.00 32.16 ? 582 PRO B CG 1 ATOM 10107 C CD . PRO B 1 562 ? 4.723 -15.992 54.869 1.00 31.52 ? 582 PRO B CD 1 ATOM 10108 N N . GLN B 1 563 ? 4.078 -14.484 58.087 1.00 32.21 ? 583 GLN B N 1 ATOM 10109 C CA . GLN B 1 563 ? 3.894 -13.506 59.155 1.00 32.31 ? 583 GLN B CA 1 ATOM 10110 C C . GLN B 1 563 ? 2.587 -13.771 59.897 1.00 32.18 ? 583 GLN B C 1 ATOM 10111 O O . GLN B 1 563 ? 1.577 -14.158 59.286 1.00 31.61 ? 583 GLN B O 1 ATOM 10112 C CB . GLN B 1 563 ? 3.829 -12.089 58.593 1.00 32.86 ? 583 GLN B CB 1 ATOM 10113 C CG . GLN B 1 563 ? 5.058 -11.606 57.864 1.00 34.38 ? 583 GLN B CG 1 ATOM 10114 C CD . GLN B 1 563 ? 4.827 -10.245 57.250 1.00 36.40 ? 583 GLN B CD 1 ATOM 10115 O OE1 . GLN B 1 563 ? 4.014 -9.463 57.745 1.00 38.86 ? 583 GLN B OE1 1 ATOM 10116 N NE2 . GLN B 1 563 ? 5.531 -9.953 56.163 1.00 37.96 ? 583 GLN B NE2 1 ATOM 10117 N N . GLU B 1 564 ? 2.613 -13.550 61.209 1.00 31.77 ? 584 GLU B N 1 ATOM 10118 C CA . GLU B 1 564 ? 1.438 -13.714 62.039 1.00 31.79 ? 584 GLU B CA 1 ATOM 10119 C C . GLU B 1 564 ? 0.924 -12.358 62.497 1.00 31.05 ? 584 GLU B C 1 ATOM 10120 O O . GLU B 1 564 ? 1.699 -11.429 62.680 1.00 31.16 ? 584 GLU B O 1 ATOM 10121 C CB . GLU B 1 564 ? 1.773 -14.566 63.254 1.00 32.31 ? 584 GLU B CB 1 ATOM 10122 C CG . GLU B 1 564 ? 2.345 -15.931 62.917 1.00 33.44 ? 584 GLU B CG 1 ATOM 10123 C CD . GLU B 1 564 ? 2.376 -16.857 64.117 1.00 35.51 ? 584 GLU B CD 1 ATOM 10124 O OE1 . GLU B 1 564 ? 2.427 -16.344 65.256 1.00 36.94 ? 584 GLU B OE1 1 ATOM 10125 O OE2 . GLU B 1 564 ? 2.340 -18.097 63.923 1.00 37.63 ? 584 GLU B OE2 1 ATOM 10126 N N . ASN B 1 565 ? -0.389 -12.247 62.680 1.00 30.14 ? 585 ASN B N 1 ATOM 10127 C CA . ASN B 1 565 ? -0.970 -11.058 63.295 1.00 29.21 ? 585 ASN B CA 1 ATOM 10128 C C . ASN B 1 565 ? -0.708 -11.094 64.816 1.00 28.78 ? 585 ASN B C 1 ATOM 10129 O O . ASN B 1 565 ? -0.167 -12.076 65.318 1.00 28.08 ? 585 ASN B O 1 ATOM 10130 C CB . ASN B 1 565 ? -2.465 -10.926 62.927 1.00 28.89 ? 585 ASN B CB 1 ATOM 10131 C CG . ASN B 1 565 ? -3.377 -11.892 63.685 1.00 28.36 ? 585 ASN B CG 1 ATOM 10132 O OD1 . ASN B 1 565 ? -2.936 -12.645 64.552 1.00 25.81 ? 585 ASN B OD1 1 ATOM 10133 N ND2 . ASN B 1 565 ? -4.677 -11.862 63.351 1.00 26.43 ? 585 ASN B ND2 1 ATOM 10134 N N . PRO B 1 566 ? -1.086 -10.034 65.552 1.00 28.51 ? 586 PRO B N 1 ATOM 10135 C CA . PRO B 1 566 ? -0.815 -10.020 67.000 1.00 28.70 ? 586 PRO B CA 1 ATOM 10136 C C . PRO B 1 566 ? -1.434 -11.146 67.826 1.00 28.50 ? 586 PRO B C 1 ATOM 10137 O O . PRO B 1 566 ? -1.040 -11.321 68.965 1.00 28.59 ? 586 PRO B O 1 ATOM 10138 C CB . PRO B 1 566 ? -1.391 -8.674 67.450 1.00 28.55 ? 586 PRO B CB 1 ATOM 10139 C CG . PRO B 1 566 ? -1.250 -7.812 66.249 1.00 28.70 ? 586 PRO B CG 1 ATOM 10140 C CD . PRO B 1 566 ? -1.593 -8.731 65.097 1.00 28.55 ? 586 PRO B CD 1 ATOM 10141 N N . TRP B 1 567 ? -2.366 -11.904 67.252 1.00 28.54 ? 587 TRP B N 1 ATOM 10142 C CA . TRP B 1 567 ? -3.104 -12.946 67.972 1.00 28.44 ? 587 TRP B CA 1 ATOM 10143 C C . TRP B 1 567 ? -2.646 -14.345 67.579 1.00 28.15 ? 587 TRP B C 1 ATOM 10144 O O . TRP B 1 567 ? -3.267 -15.342 67.967 1.00 28.39 ? 587 TRP B O 1 ATOM 10145 C CB . TRP B 1 567 ? -4.614 -12.764 67.724 1.00 28.84 ? 587 TRP B CB 1 ATOM 10146 C CG . TRP B 1 567 ? -4.973 -11.312 67.801 1.00 29.66 ? 587 TRP B CG 1 ATOM 10147 C CD1 . TRP B 1 567 ? -5.444 -10.521 66.791 1.00 30.67 ? 587 TRP B CD1 1 ATOM 10148 C CD2 . TRP B 1 567 ? -4.792 -10.456 68.929 1.00 30.42 ? 587 TRP B CD2 1 ATOM 10149 N NE1 . TRP B 1 567 ? -5.600 -9.231 67.235 1.00 30.09 ? 587 TRP B NE1 1 ATOM 10150 C CE2 . TRP B 1 567 ? -5.208 -9.166 68.546 1.00 31.07 ? 587 TRP B CE2 1 ATOM 10151 C CE3 . TRP B 1 567 ? -4.334 -10.659 70.236 1.00 31.56 ? 587 TRP B CE3 1 ATOM 10152 C CZ2 . TRP B 1 567 ? -5.178 -8.078 69.426 1.00 32.44 ? 587 TRP B CZ2 1 ATOM 10153 C CZ3 . TRP B 1 567 ? -4.310 -9.581 71.110 1.00 31.20 ? 587 TRP B CZ3 1 ATOM 10154 C CH2 . TRP B 1 567 ? -4.724 -8.308 70.701 1.00 32.77 ? 587 TRP B CH2 1 ATOM 10155 N N . GLY B 1 568 ? -1.562 -14.417 66.807 1.00 27.57 ? 588 GLY B N 1 ATOM 10156 C CA . GLY B 1 568 ? -0.935 -15.689 66.468 1.00 27.59 ? 588 GLY B CA 1 ATOM 10157 C C . GLY B 1 568 ? -1.454 -16.370 65.213 1.00 27.58 ? 588 GLY B C 1 ATOM 10158 O O . GLY B 1 568 ? -1.110 -17.521 64.955 1.00 28.57 ? 588 GLY B O 1 ATOM 10159 N N . HIS B 1 569 ? -2.289 -15.693 64.434 1.00 26.79 ? 589 HIS B N 1 ATOM 10160 C CA . HIS B 1 569 ? -2.846 -16.301 63.227 1.00 26.52 ? 589 HIS B CA 1 ATOM 10161 C C . HIS B 1 569 ? -2.128 -15.762 62.007 1.00 26.37 ? 589 HIS B C 1 ATOM 10162 O O . HIS B 1 569 ? -1.764 -14.591 61.971 1.00 26.70 ? 589 HIS B O 1 ATOM 10163 C CB . HIS B 1 569 ? -4.350 -16.028 63.133 1.00 26.03 ? 589 HIS B CB 1 ATOM 10164 C CG . HIS B 1 569 ? -5.144 -16.758 64.165 1.00 25.66 ? 589 HIS B CG 1 ATOM 10165 N ND1 . HIS B 1 569 ? -5.520 -18.075 64.017 1.00 25.47 ? 589 HIS B ND1 1 ATOM 10166 C CD2 . HIS B 1 569 ? -5.601 -16.368 65.377 1.00 24.97 ? 589 HIS B CD2 1 ATOM 10167 C CE1 . HIS B 1 569 ? -6.181 -18.464 65.093 1.00 26.38 ? 589 HIS B CE1 1 ATOM 10168 N NE2 . HIS B 1 569 ? -6.245 -17.447 65.933 1.00 24.73 ? 589 HIS B NE2 1 ATOM 10169 N N . LYS B 1 570 ? -1.929 -16.611 61.005 1.00 26.34 ? 590 LYS B N 1 ATOM 10170 C CA . LYS B 1 570 ? -1.222 -16.195 59.794 1.00 26.28 ? 590 LYS B CA 1 ATOM 10171 C C . LYS B 1 570 ? -1.977 -15.106 59.036 1.00 26.04 ? 590 LYS B C 1 ATOM 10172 O O . LYS B 1 570 ? -3.200 -15.172 58.884 1.00 25.84 ? 590 LYS B O 1 ATOM 10173 C CB . LYS B 1 570 ? -0.970 -17.393 58.883 1.00 26.64 ? 590 LYS B CB 1 ATOM 10174 C CG . LYS B 1 570 ? 0.260 -18.222 59.270 1.00 27.14 ? 590 LYS B CG 1 ATOM 10175 C CD . LYS B 1 570 ? 0.562 -19.260 58.187 1.00 27.90 ? 590 LYS B CD 1 ATOM 10176 N N . ARG B 1 571 ? -1.240 -14.098 58.573 1.00 25.76 ? 591 ARG B N 1 ATOM 10177 C CA . ARG B 1 571 ? -1.829 -13.004 57.809 1.00 25.80 ? 591 ARG B CA 1 ATOM 10178 C C . ARG B 1 571 ? -2.204 -13.509 56.419 1.00 25.52 ? 591 ARG B C 1 ATOM 10179 O O . ARG B 1 571 ? -1.356 -14.059 55.704 1.00 25.59 ? 591 ARG B O 1 ATOM 10180 C CB . ARG B 1 571 ? -0.873 -11.825 57.727 1.00 25.99 ? 591 ARG B CB 1 ATOM 10181 C CG . ARG B 1 571 ? -0.410 -11.340 59.100 1.00 27.34 ? 591 ARG B CG 1 ATOM 10182 C CD . ARG B 1 571 ? 0.517 -10.181 58.964 1.00 27.91 ? 591 ARG B CD 1 ATOM 10183 N NE . ARG B 1 571 ? -0.213 -8.976 58.569 1.00 29.45 ? 591 ARG B NE 1 ATOM 10184 C CZ . ARG B 1 571 ? 0.329 -7.942 57.939 1.00 30.61 ? 591 ARG B CZ 1 ATOM 10185 N NH1 . ARG B 1 571 ? 1.622 -7.951 57.605 1.00 31.34 ? 591 ARG B NH1 1 ATOM 10186 N NH2 . ARG B 1 571 ? -0.429 -6.897 57.631 1.00 31.67 ? 591 ARG B NH2 1 ATOM 10187 N N . SER B 1 572 ? -3.478 -13.357 56.050 1.00 24.91 ? 592 SER B N 1 ATOM 10188 C CA A SER B 1 572 ? -4.006 -13.930 54.807 0.60 24.49 ? 592 SER B CA 1 ATOM 10189 C CA B SER B 1 572 ? -3.933 -13.874 54.763 0.40 24.74 ? 592 SER B CA 1 ATOM 10190 C C . SER B 1 572 ? -5.004 -13.017 54.104 1.00 24.30 ? 592 SER B C 1 ATOM 10191 O O . SER B 1 572 ? -5.554 -12.096 54.718 1.00 24.13 ? 592 SER B O 1 ATOM 10192 C CB A SER B 1 572 ? -4.716 -15.256 55.099 0.60 24.42 ? 592 SER B CB 1 ATOM 10193 C CB B SER B 1 572 ? -4.443 -15.302 54.933 0.40 24.76 ? 592 SER B CB 1 ATOM 10194 O OG A SER B 1 572 ? -3.957 -16.105 55.941 0.60 23.52 ? 592 SER B OG 1 ATOM 10195 O OG B SER B 1 572 ? -5.591 -15.328 55.750 0.40 25.29 ? 592 SER B OG 1 ATOM 10196 N N . TYR B 1 573 ? -5.247 -13.311 52.825 1.00 23.82 ? 593 TYR B N 1 ATOM 10197 C CA . TYR B 1 573 ? -6.391 -12.786 52.089 1.00 23.17 ? 593 TYR B CA 1 ATOM 10198 C C . TYR B 1 573 ? -7.213 -13.971 51.593 1.00 23.25 ? 593 TYR B C 1 ATOM 10199 O O . TYR B 1 573 ? -6.676 -15.006 51.178 1.00 23.63 ? 593 TYR B O 1 ATOM 10200 C CB . TYR B 1 573 ? -5.972 -11.855 50.934 1.00 23.37 ? 593 TYR B CB 1 ATOM 10201 C CG . TYR B 1 573 ? -6.216 -10.398 51.247 1.00 21.61 ? 593 TYR B CG 1 ATOM 10202 C CD1 . TYR B 1 573 ? -5.378 -9.710 52.120 1.00 21.05 ? 593 TYR B CD1 1 ATOM 10203 C CD2 . TYR B 1 573 ? -7.314 -9.718 50.707 1.00 20.96 ? 593 TYR B CD2 1 ATOM 10204 C CE1 . TYR B 1 573 ? -5.600 -8.378 52.431 1.00 20.97 ? 593 TYR B CE1 1 ATOM 10205 C CE2 . TYR B 1 573 ? -7.553 -8.385 51.005 1.00 20.13 ? 593 TYR B CE2 1 ATOM 10206 C CZ . TYR B 1 573 ? -6.692 -7.713 51.880 1.00 21.87 ? 593 TYR B CZ 1 ATOM 10207 O OH . TYR B 1 573 ? -6.912 -6.394 52.215 1.00 19.79 ? 593 TYR B OH 1 ATOM 10208 N N . ARG B 1 574 ? -8.525 -13.818 51.658 1.00 23.07 ? 594 ARG B N 1 ATOM 10209 C CA . ARG B 1 574 ? -9.461 -14.857 51.273 1.00 22.84 ? 594 ARG B CA 1 ATOM 10210 C C . ARG B 1 574 ? -10.040 -14.539 49.891 1.00 22.53 ? 594 ARG B C 1 ATOM 10211 O O . ARG B 1 574 ? -10.409 -13.395 49.621 1.00 22.08 ? 594 ARG B O 1 ATOM 10212 C CB . ARG B 1 574 ? -10.583 -14.905 52.314 1.00 22.96 ? 594 ARG B CB 1 ATOM 10213 C CG . ARG B 1 574 ? -11.646 -15.925 52.060 1.00 23.73 ? 594 ARG B CG 1 ATOM 10214 C CD . ARG B 1 574 ? -12.884 -15.620 52.881 1.00 23.45 ? 594 ARG B CD 1 ATOM 10215 N NE . ARG B 1 574 ? -13.930 -16.597 52.614 1.00 23.45 ? 594 ARG B NE 1 ATOM 10216 C CZ . ARG B 1 574 ? -15.116 -16.605 53.214 1.00 24.56 ? 594 ARG B CZ 1 ATOM 10217 N NH1 . ARG B 1 574 ? -15.415 -15.681 54.114 1.00 24.74 ? 594 ARG B NH1 1 ATOM 10218 N NH2 . ARG B 1 574 ? -16.013 -17.534 52.905 1.00 24.94 ? 594 ARG B NH2 1 ATOM 10219 N N . LEU B 1 575 ? -10.116 -15.550 49.026 1.00 22.40 ? 595 LEU B N 1 ATOM 10220 C CA . LEU B 1 575 ? -10.765 -15.415 47.723 1.00 22.56 ? 595 LEU B CA 1 ATOM 10221 C C . LEU B 1 575 ? -12.166 -16.015 47.805 1.00 22.61 ? 595 LEU B C 1 ATOM 10222 O O . LEU B 1 575 ? -12.327 -17.157 48.198 1.00 22.92 ? 595 LEU B O 1 ATOM 10223 C CB . LEU B 1 575 ? -9.949 -16.107 46.627 1.00 22.48 ? 595 LEU B CB 1 ATOM 10224 C CG . LEU B 1 575 ? -10.616 -16.294 45.259 1.00 22.41 ? 595 LEU B CG 1 ATOM 10225 C CD1 . LEU B 1 575 ? -10.858 -14.963 44.559 1.00 22.68 ? 595 LEU B CD1 1 ATOM 10226 C CD2 . LEU B 1 575 ? -9.758 -17.221 44.391 1.00 23.39 ? 595 LEU B CD2 1 ATOM 10227 N N . GLN B 1 576 ? -13.166 -15.223 47.435 1.00 23.28 ? 596 GLN B N 1 ATOM 10228 C CA . GLN B 1 576 ? -14.577 -15.622 47.477 1.00 23.72 ? 596 GLN B CA 1 ATOM 10229 C C . GLN B 1 576 ? -15.191 -15.395 46.100 1.00 23.35 ? 596 GLN B C 1 ATOM 10230 O O . GLN B 1 576 ? -15.313 -14.255 45.648 1.00 23.30 ? 596 GLN B O 1 ATOM 10231 C CB . GLN B 1 576 ? -15.287 -14.780 48.534 1.00 24.38 ? 596 GLN B CB 1 ATOM 10232 C CG . GLN B 1 576 ? -16.758 -15.039 48.748 1.00 26.29 ? 596 GLN B CG 1 ATOM 10233 C CD . GLN B 1 576 ? -17.293 -14.233 49.930 1.00 29.00 ? 596 GLN B CD 1 ATOM 10234 O OE1 . GLN B 1 576 ? -16.611 -14.077 50.944 1.00 30.14 ? 596 GLN B OE1 1 ATOM 10235 N NE2 . GLN B 1 576 ? -18.508 -13.708 49.796 1.00 29.79 ? 596 GLN B NE2 1 ATOM 10236 N N . ILE B 1 577 ? -15.579 -16.484 45.445 1.00 22.95 ? 597 ILE B N 1 ATOM 10237 C CA . ILE B 1 577 ? -15.992 -16.462 44.049 1.00 22.67 ? 597 ILE B CA 1 ATOM 10238 C C . ILE B 1 577 ? -17.513 -16.385 43.920 1.00 23.00 ? 597 ILE B C 1 ATOM 10239 O O . ILE B 1 577 ? -18.242 -17.150 44.567 1.00 22.84 ? 597 ILE B O 1 ATOM 10240 C CB . ILE B 1 577 ? -15.486 -17.729 43.314 1.00 22.50 ? 597 ILE B CB 1 ATOM 10241 C CG1 . ILE B 1 577 ? -13.951 -17.774 43.317 1.00 22.17 ? 597 ILE B CG1 1 ATOM 10242 C CG2 . ILE B 1 577 ? -16.019 -17.782 41.894 1.00 22.35 ? 597 ILE B CG2 1 ATOM 10243 C CD1 . ILE B 1 577 ? -13.350 -19.170 43.026 1.00 20.11 ? 597 ILE B CD1 1 ATOM 10244 N N A HIS B 1 578 ? -17.984 -15.473 43.077 0.50 22.98 ? 598 HIS B N 1 ATOM 10245 N N B HIS B 1 578 ? -17.983 -15.447 43.097 0.50 23.05 ? 598 HIS B N 1 ATOM 10246 C CA A HIS B 1 578 ? -19.409 -15.339 42.805 0.50 23.10 ? 598 HIS B CA 1 ATOM 10247 C CA B HIS B 1 578 ? -19.406 -15.317 42.780 0.50 23.21 ? 598 HIS B CA 1 ATOM 10248 C C A HIS B 1 578 ? -19.654 -15.716 41.346 0.50 22.98 ? 598 HIS B C 1 ATOM 10249 C C B HIS B 1 578 ? -19.615 -15.736 41.332 0.50 23.03 ? 598 HIS B C 1 ATOM 10250 O O A HIS B 1 578 ? -19.364 -14.936 40.432 0.50 22.69 ? 598 HIS B O 1 ATOM 10251 O O B HIS B 1 578 ? -19.271 -14.993 40.406 0.50 22.72 ? 598 HIS B O 1 ATOM 10252 C CB A HIS B 1 578 ? -19.883 -13.922 43.133 0.50 23.20 ? 598 HIS B CB 1 ATOM 10253 C CB B HIS B 1 578 ? -19.894 -13.883 42.980 0.50 23.34 ? 598 HIS B CB 1 ATOM 10254 C CG A HIS B 1 578 ? -19.774 -13.581 44.589 0.50 23.73 ? 598 HIS B CG 1 ATOM 10255 C CG B HIS B 1 578 ? -21.358 -13.707 42.718 0.50 24.26 ? 598 HIS B CG 1 ATOM 10256 N ND1 A HIS B 1 578 ? -19.455 -12.320 45.043 0.50 24.60 ? 598 HIS B ND1 1 ATOM 10257 N ND1 B HIS B 1 578 ? -21.843 -12.942 41.679 0.50 25.60 ? 598 HIS B ND1 1 ATOM 10258 C CD2 A HIS B 1 578 ? -19.922 -14.350 45.695 0.50 24.71 ? 598 HIS B CD2 1 ATOM 10259 C CD2 B HIS B 1 578 ? -22.444 -14.216 43.348 0.50 25.13 ? 598 HIS B CD2 1 ATOM 10260 C CE1 A HIS B 1 578 ? -19.426 -12.324 46.364 0.50 24.69 ? 598 HIS B CE1 1 ATOM 10261 C CE1 B HIS B 1 578 ? -23.164 -12.979 41.686 0.50 25.30 ? 598 HIS B CE1 1 ATOM 10262 N NE2 A HIS B 1 578 ? -19.701 -13.544 46.785 0.50 24.77 ? 598 HIS B NE2 1 ATOM 10263 N NE2 B HIS B 1 578 ? -23.554 -13.744 42.689 0.50 24.91 ? 598 HIS B NE2 1 ATOM 10264 N N . SER B 1 579 ? -20.166 -16.930 41.141 1.00 22.75 ? 599 SER B N 1 ATOM 10265 C CA . SER B 1 579 ? -20.248 -17.529 39.807 1.00 22.98 ? 599 SER B CA 1 ATOM 10266 C C . SER B 1 579 ? -21.335 -18.594 39.692 1.00 23.35 ? 599 SER B C 1 ATOM 10267 O O . SER B 1 579 ? -21.710 -19.209 40.676 1.00 22.72 ? 599 SER B O 1 ATOM 10268 C CB . SER B 1 579 ? -18.895 -18.169 39.477 1.00 22.41 ? 599 SER B CB 1 ATOM 10269 O OG . SER B 1 579 ? -18.915 -18.800 38.212 1.00 21.16 ? 599 SER B OG 1 ATOM 10270 N N . MET B 1 580 ? -21.836 -18.791 38.480 1.00 24.31 ? 600 MET B N 1 ATOM 10271 C CA A MET B 1 580 ? -22.739 -19.910 38.208 0.70 25.17 ? 600 MET B CA 1 ATOM 10272 C CA B MET B 1 580 ? -22.753 -19.885 38.165 0.30 24.84 ? 600 MET B CA 1 ATOM 10273 C C . MET B 1 580 ? -22.128 -20.850 37.163 1.00 25.08 ? 600 MET B C 1 ATOM 10274 O O . MET B 1 580 ? -22.809 -21.712 36.630 1.00 26.03 ? 600 MET B O 1 ATOM 10275 C CB A MET B 1 580 ? -24.113 -19.400 37.761 0.70 25.53 ? 600 MET B CB 1 ATOM 10276 C CB B MET B 1 580 ? -24.066 -19.336 37.597 0.30 24.91 ? 600 MET B CB 1 ATOM 10277 C CG A MET B 1 580 ? -24.836 -18.559 38.810 0.70 27.16 ? 600 MET B CG 1 ATOM 10278 C CG B MET B 1 580 ? -25.237 -19.496 38.526 0.30 25.36 ? 600 MET B CG 1 ATOM 10279 S SD A MET B 1 580 ? -26.570 -18.213 38.370 0.70 31.65 ? 600 MET B SD 1 ATOM 10280 S SD B MET B 1 580 ? -25.051 -18.511 40.014 0.30 25.72 ? 600 MET B SD 1 ATOM 10281 C CE A MET B 1 580 ? -26.366 -17.057 37.011 0.70 30.41 ? 600 MET B CE 1 ATOM 10282 C CE B MET B 1 580 ? -26.579 -18.908 40.874 0.30 25.26 ? 600 MET B CE 1 ATOM 10283 N N . ALA B 1 581 ? -20.825 -20.711 36.910 1.00 25.35 ? 601 ALA B N 1 ATOM 10284 C CA . ALA B 1 581 ? -20.154 -21.500 35.869 1.00 25.17 ? 601 ALA B CA 1 ATOM 10285 C C . ALA B 1 581 ? -20.088 -22.993 36.148 1.00 25.41 ? 601 ALA B C 1 ATOM 10286 O O . ALA B 1 581 ? -20.266 -23.464 37.275 1.00 25.04 ? 601 ALA B O 1 ATOM 10287 C CB . ALA B 1 581 ? -18.754 -20.963 35.592 1.00 24.91 ? 601 ALA B CB 1 ATOM 10288 N N . ASP B 1 582 ? -19.830 -23.727 35.076 1.00 25.95 ? 602 ASP B N 1 ATOM 10289 C CA . ASP B 1 582 ? -19.705 -25.176 35.107 1.00 26.34 ? 602 ASP B CA 1 ATOM 10290 C C . ASP B 1 582 ? -18.830 -25.580 33.933 1.00 25.90 ? 602 ASP B C 1 ATOM 10291 O O . ASP B 1 582 ? -18.468 -24.731 33.112 1.00 25.47 ? 602 ASP B O 1 ATOM 10292 C CB . ASP B 1 582 ? -21.094 -25.797 34.950 1.00 26.69 ? 602 ASP B CB 1 ATOM 10293 C CG . ASP B 1 582 ? -21.189 -27.175 35.544 1.00 28.59 ? 602 ASP B CG 1 ATOM 10294 O OD1 . ASP B 1 582 ? -20.135 -27.796 35.852 1.00 31.36 ? 602 ASP B OD1 1 ATOM 10295 O OD2 . ASP B 1 582 ? -22.334 -27.642 35.691 1.00 31.48 ? 602 ASP B OD2 1 ATOM 10296 N N . GLN B 1 583 ? -18.497 -26.865 33.843 1.00 26.09 ? 603 GLN B N 1 ATOM 10297 C CA . GLN B 1 583 ? -17.833 -27.391 32.654 1.00 26.18 ? 603 GLN B CA 1 ATOM 10298 C C . GLN B 1 583 ? -18.763 -27.273 31.456 1.00 26.22 ? 603 GLN B C 1 ATOM 10299 O O . GLN B 1 583 ? -19.912 -27.732 31.506 1.00 26.20 ? 603 GLN B O 1 ATOM 10300 C CB . GLN B 1 583 ? -17.427 -28.858 32.842 1.00 26.38 ? 603 GLN B CB 1 ATOM 10301 C CG . GLN B 1 583 ? -16.453 -29.345 31.770 1.00 26.25 ? 603 GLN B CG 1 ATOM 10302 C CD . GLN B 1 583 ? -15.194 -28.489 31.731 1.00 25.74 ? 603 GLN B CD 1 ATOM 10303 O OE1 . GLN B 1 583 ? -14.561 -28.279 32.755 1.00 26.05 ? 603 GLN B OE1 1 ATOM 10304 N NE2 . GLN B 1 583 ? -14.839 -27.987 30.552 1.00 25.70 ? 603 GLN B NE2 1 ATOM 10305 N N . VAL B 1 584 ? -18.282 -26.645 30.386 1.00 26.38 ? 604 VAL B N 1 ATOM 10306 C CA . VAL B 1 584 ? -19.104 -26.440 29.202 1.00 26.60 ? 604 VAL B CA 1 ATOM 10307 C C . VAL B 1 584 ? -18.719 -27.441 28.122 1.00 26.92 ? 604 VAL B C 1 ATOM 10308 O O . VAL B 1 584 ? -19.517 -28.311 27.775 1.00 27.10 ? 604 VAL B O 1 ATOM 10309 C CB . VAL B 1 584 ? -19.011 -24.996 28.673 1.00 26.76 ? 604 VAL B CB 1 ATOM 10310 C CG1 . VAL B 1 584 ? -19.891 -24.826 27.435 1.00 26.49 ? 604 VAL B CG1 1 ATOM 10311 C CG2 . VAL B 1 584 ? -19.421 -24.007 29.763 1.00 26.86 ? 604 VAL B CG2 1 ATOM 10312 N N . LEU B 1 585 ? -17.499 -27.323 27.604 1.00 27.02 ? 605 LEU B N 1 ATOM 10313 C CA . LEU B 1 585 ? -17.022 -28.242 26.576 1.00 27.25 ? 605 LEU B CA 1 ATOM 10314 C C . LEU B 1 585 ? -16.372 -29.466 27.221 1.00 26.96 ? 605 LEU B C 1 ATOM 10315 O O . LEU B 1 585 ? -15.899 -29.382 28.351 1.00 27.35 ? 605 LEU B O 1 ATOM 10316 C CB . LEU B 1 585 ? -16.046 -27.539 25.625 1.00 27.19 ? 605 LEU B CB 1 ATOM 10317 C CG . LEU B 1 585 ? -16.629 -26.305 24.925 1.00 27.89 ? 605 LEU B CG 1 ATOM 10318 C CD1 . LEU B 1 585 ? -15.579 -25.609 24.044 1.00 29.31 ? 605 LEU B CD1 1 ATOM 10319 C CD2 . LEU B 1 585 ? -17.877 -26.656 24.110 1.00 28.20 ? 605 LEU B CD2 1 ATOM 10320 N N . PRO B 1 586 ? -16.374 -30.616 26.518 1.00 26.60 ? 606 PRO B N 1 ATOM 10321 C CA . PRO B 1 586 ? -15.678 -31.795 27.043 1.00 26.05 ? 606 PRO B CA 1 ATOM 10322 C C . PRO B 1 586 ? -14.167 -31.594 27.073 1.00 25.91 ? 606 PRO B C 1 ATOM 10323 O O . PRO B 1 586 ? -13.576 -31.228 26.060 1.00 25.13 ? 606 PRO B O 1 ATOM 10324 C CB . PRO B 1 586 ? -16.032 -32.907 26.048 1.00 25.99 ? 606 PRO B CB 1 ATOM 10325 C CG . PRO B 1 586 ? -17.146 -32.368 25.207 1.00 26.65 ? 606 PRO B CG 1 ATOM 10326 C CD . PRO B 1 586 ? -17.019 -30.885 25.222 1.00 26.63 ? 606 PRO B CD 1 ATOM 10327 N N . PRO B 1 587 ? -13.538 -31.833 28.229 1.00 25.87 ? 607 PRO B N 1 ATOM 10328 C CA . PRO B 1 587 ? -12.088 -31.758 28.264 1.00 26.14 ? 607 PRO B CA 1 ATOM 10329 C C . PRO B 1 587 ? -11.441 -32.613 27.183 1.00 26.29 ? 607 PRO B C 1 ATOM 10330 O O . PRO B 1 587 ? -11.786 -33.778 27.049 1.00 26.72 ? 607 PRO B O 1 ATOM 10331 C CB . PRO B 1 587 ? -11.756 -32.289 29.656 1.00 25.96 ? 607 PRO B CB 1 ATOM 10332 C CG . PRO B 1 587 ? -12.897 -31.815 30.479 1.00 26.02 ? 607 PRO B CG 1 ATOM 10333 C CD . PRO B 1 587 ? -14.100 -32.048 29.574 1.00 26.01 ? 607 PRO B CD 1 ATOM 10334 N N . GLY B 1 588 ? -10.539 -32.021 26.404 1.00 26.56 ? 608 GLY B N 1 ATOM 10335 C CA . GLY B 1 588 ? -9.768 -32.761 25.414 1.00 26.61 ? 608 GLY B CA 1 ATOM 10336 C C . GLY B 1 588 ? -10.377 -32.737 24.033 1.00 26.97 ? 608 GLY B C 1 ATOM 10337 O O . GLY B 1 588 ? -9.750 -33.199 23.087 1.00 27.25 ? 608 GLY B O 1 ATOM 10338 N N . TRP B 1 589 ? -11.579 -32.176 23.889 1.00 27.05 ? 609 TRP B N 1 ATOM 10339 C CA . TRP B 1 589 ? -12.265 -32.207 22.599 1.00 27.23 ? 609 TRP B CA 1 ATOM 10340 C C . TRP B 1 589 ? -12.075 -30.937 21.763 1.00 27.00 ? 609 TRP B C 1 ATOM 10341 O O . TRP B 1 589 ? -12.655 -29.899 22.057 1.00 27.02 ? 609 TRP B O 1 ATOM 10342 C CB . TRP B 1 589 ? -13.759 -32.491 22.773 1.00 27.36 ? 609 TRP B CB 1 ATOM 10343 C CG . TRP B 1 589 ? -14.455 -32.499 21.446 1.00 28.64 ? 609 TRP B CG 1 ATOM 10344 C CD1 . TRP B 1 589 ? -15.245 -31.519 20.927 1.00 28.97 ? 609 TRP B CD1 1 ATOM 10345 C CD2 . TRP B 1 589 ? -14.364 -33.516 20.445 1.00 29.85 ? 609 TRP B CD2 1 ATOM 10346 N NE1 . TRP B 1 589 ? -15.685 -31.879 19.673 1.00 29.69 ? 609 TRP B NE1 1 ATOM 10347 C CE2 . TRP B 1 589 ? -15.156 -33.099 19.353 1.00 30.10 ? 609 TRP B CE2 1 ATOM 10348 C CE3 . TRP B 1 589 ? -13.709 -34.752 20.375 1.00 30.18 ? 609 TRP B CE3 1 ATOM 10349 C CZ2 . TRP B 1 589 ? -15.299 -33.866 18.198 1.00 30.87 ? 609 TRP B CZ2 1 ATOM 10350 C CZ3 . TRP B 1 589 ? -13.853 -35.517 19.229 1.00 30.34 ? 609 TRP B CZ3 1 ATOM 10351 C CH2 . TRP B 1 589 ? -14.647 -35.074 18.157 1.00 30.87 ? 609 TRP B CH2 1 ATOM 10352 N N . GLN B 1 590 ? -11.258 -31.048 20.716 1.00 27.09 ? 610 GLN B N 1 ATOM 10353 C CA . GLN B 1 590 ? -11.102 -30.030 19.676 1.00 26.99 ? 610 GLN B CA 1 ATOM 10354 C C . GLN B 1 590 ? -10.891 -28.604 20.224 1.00 26.67 ? 610 GLN B C 1 ATOM 10355 O O . GLN B 1 590 ? -9.834 -28.318 20.803 1.00 26.23 ? 610 GLN B O 1 ATOM 10356 C CB . GLN B 1 590 ? -12.284 -30.102 18.686 1.00 27.29 ? 610 GLN B CB 1 ATOM 10357 C CG . GLN B 1 590 ? -12.441 -31.438 17.935 1.00 28.91 ? 610 GLN B CG 1 ATOM 10358 C CD . GLN B 1 590 ? -11.275 -31.770 16.993 1.00 30.89 ? 610 GLN B CD 1 ATOM 10359 O OE1 . GLN B 1 590 ? -10.514 -30.899 16.579 1.00 31.19 ? 610 GLN B OE1 1 ATOM 10360 N NE2 . GLN B 1 590 ? -11.152 -33.039 16.646 1.00 32.79 ? 610 GLN B NE2 1 ATOM 10361 N N . GLU B 1 591 ? -11.893 -27.726 20.059 1.00 26.24 ? 611 GLU B N 1 ATOM 10362 C CA . GLU B 1 591 ? -11.768 -26.290 20.398 1.00 26.18 ? 611 GLU B CA 1 ATOM 10363 C C . GLU B 1 591 ? -11.596 -26.028 21.895 1.00 25.28 ? 611 GLU B C 1 ATOM 10364 O O . GLU B 1 591 ? -11.139 -24.966 22.275 1.00 24.91 ? 611 GLU B O 1 ATOM 10365 C CB . GLU B 1 591 ? -12.981 -25.478 19.908 1.00 26.33 ? 611 GLU B CB 1 ATOM 10366 C CG . GLU B 1 591 ? -13.259 -25.561 18.406 1.00 28.04 ? 611 GLU B CG 1 ATOM 10367 C CD . GLU B 1 591 ? -14.033 -26.800 18.025 1.00 30.72 ? 611 GLU B CD 1 ATOM 10368 O OE1 . GLU B 1 591 ? -14.718 -27.371 18.898 1.00 33.68 ? 611 GLU B OE1 1 ATOM 10369 O OE2 . GLU B 1 591 ? -13.948 -27.220 16.857 1.00 35.35 ? 611 GLU B OE2 1 ATOM 10370 N N . GLU B 1 592 ? -11.973 -26.990 22.733 1.00 24.89 ? 612 GLU B N 1 ATOM 10371 C CA . GLU B 1 592 ? -11.808 -26.870 24.184 1.00 24.74 ? 612 GLU B CA 1 ATOM 10372 C C . GLU B 1 592 ? -10.342 -26.622 24.558 1.00 24.76 ? 612 GLU B C 1 ATOM 10373 O O . GLU B 1 592 ? -10.057 -26.055 25.600 1.00 25.07 ? 612 GLU B O 1 ATOM 10374 C CB . GLU B 1 592 ? -12.367 -28.117 24.887 1.00 24.34 ? 612 GLU B CB 1 ATOM 10375 C CG . GLU B 1 592 ? -12.481 -27.999 26.406 1.00 24.09 ? 612 GLU B CG 1 ATOM 10376 C CD . GLU B 1 592 ? -11.193 -28.363 27.170 1.00 23.36 ? 612 GLU B CD 1 ATOM 10377 O OE1 . GLU B 1 592 ? -10.315 -29.047 26.604 1.00 22.11 ? 612 GLU B OE1 1 ATOM 10378 O OE2 . GLU B 1 592 ? -11.070 -27.972 28.350 1.00 21.47 ? 612 GLU B OE2 1 ATOM 10379 N N . GLN B 1 593 ? -9.419 -27.018 23.682 1.00 24.98 ? 613 GLN B N 1 ATOM 10380 C CA . GLN B 1 593 ? -7.992 -26.746 23.860 1.00 24.82 ? 613 GLN B CA 1 ATOM 10381 C C . GLN B 1 593 ? -7.714 -25.261 24.042 1.00 24.69 ? 613 GLN B C 1 ATOM 10382 O O . GLN B 1 593 ? -6.745 -24.875 24.704 1.00 24.91 ? 613 GLN B O 1 ATOM 10383 C CB . GLN B 1 593 ? -7.205 -27.299 22.664 1.00 25.07 ? 613 GLN B CB 1 ATOM 10384 C CG . GLN B 1 593 ? -5.691 -27.396 22.850 1.00 26.29 ? 613 GLN B CG 1 ATOM 10385 C CD . GLN B 1 593 ? -5.276 -28.413 23.899 1.00 27.90 ? 613 GLN B CD 1 ATOM 10386 O OE1 . GLN B 1 593 ? -6.092 -28.893 24.692 1.00 29.39 ? 613 GLN B OE1 1 ATOM 10387 N NE2 . GLN B 1 593 ? -3.995 -28.728 23.924 1.00 29.67 ? 613 GLN B NE2 1 ATOM 10388 N N . ALA B 1 594 ? -8.569 -24.421 23.457 1.00 24.22 ? 614 ALA B N 1 ATOM 10389 C CA . ALA B 1 594 ? -8.418 -22.978 23.576 1.00 23.40 ? 614 ALA B CA 1 ATOM 10390 C C . ALA B 1 594 ? -8.778 -22.460 24.969 1.00 22.62 ? 614 ALA B C 1 ATOM 10391 O O . ALA B 1 594 ? -8.308 -21.400 25.361 1.00 22.52 ? 614 ALA B O 1 ATOM 10392 C CB . ALA B 1 594 ? -9.266 -22.269 22.506 1.00 23.31 ? 614 ALA B CB 1 ATOM 10393 N N . ILE B 1 595 ? -9.607 -23.198 25.708 1.00 22.02 ? 615 ILE B N 1 ATOM 10394 C CA . ILE B 1 595 ? -10.156 -22.715 26.980 1.00 21.25 ? 615 ILE B CA 1 ATOM 10395 C C . ILE B 1 595 ? -10.040 -23.728 28.133 1.00 20.87 ? 615 ILE B C 1 ATOM 10396 O O . ILE B 1 595 ? -10.998 -23.941 28.902 1.00 20.78 ? 615 ILE B O 1 ATOM 10397 C CB . ILE B 1 595 ? -11.631 -22.255 26.809 1.00 21.19 ? 615 ILE B CB 1 ATOM 10398 C CG1 . ILE B 1 595 ? -12.533 -23.384 26.306 1.00 20.49 ? 615 ILE B CG1 1 ATOM 10399 C CG2 . ILE B 1 595 ? -11.712 -21.059 25.834 1.00 20.67 ? 615 ILE B CG2 1 ATOM 10400 C CD1 . ILE B 1 595 ? -14.060 -23.075 26.503 1.00 19.46 ? 615 ILE B CD1 1 ATOM 10401 N N . THR B 1 596 ? -8.850 -24.306 28.279 1.00 20.13 ? 616 THR B N 1 ATOM 10402 C CA . THR B 1 596 ? -8.584 -25.308 29.322 1.00 19.96 ? 616 THR B CA 1 ATOM 10403 C C . THR B 1 596 ? -8.635 -24.694 30.713 1.00 20.27 ? 616 THR B C 1 ATOM 10404 O O . THR B 1 596 ? -8.850 -25.390 31.709 1.00 20.88 ? 616 THR B O 1 ATOM 10405 C CB . THR B 1 596 ? -7.206 -26.023 29.122 1.00 19.94 ? 616 THR B CB 1 ATOM 10406 O OG1 . THR B 1 596 ? -6.133 -25.067 29.156 1.00 18.83 ? 616 THR B OG1 1 ATOM 10407 C CG2 . THR B 1 596 ? -7.187 -26.773 27.798 1.00 19.38 ? 616 THR B CG2 1 ATOM 10408 N N . TRP B 1 597 ? -8.428 -23.389 30.783 1.00 20.41 ? 617 TRP B N 1 ATOM 10409 C CA . TRP B 1 597 ? -8.599 -22.665 32.022 1.00 20.53 ? 617 TRP B CA 1 ATOM 10410 C C . TRP B 1 597 ? -10.032 -22.793 32.568 1.00 21.15 ? 617 TRP B C 1 ATOM 10411 O O . TRP B 1 597 ? -10.220 -22.823 33.784 1.00 21.29 ? 617 TRP B O 1 ATOM 10412 C CB . TRP B 1 597 ? -8.206 -21.197 31.842 1.00 20.63 ? 617 TRP B CB 1 ATOM 10413 C CG . TRP B 1 597 ? -8.847 -20.465 30.682 1.00 19.80 ? 617 TRP B CG 1 ATOM 10414 C CD1 . TRP B 1 597 ? -8.281 -20.201 29.464 1.00 20.58 ? 617 TRP B CD1 1 ATOM 10415 C CD2 . TRP B 1 597 ? -10.156 -19.872 30.651 1.00 18.41 ? 617 TRP B CD2 1 ATOM 10416 N NE1 . TRP B 1 597 ? -9.166 -19.490 28.673 1.00 18.98 ? 617 TRP B NE1 1 ATOM 10417 C CE2 . TRP B 1 597 ? -10.317 -19.274 29.383 1.00 17.98 ? 617 TRP B CE2 1 ATOM 10418 C CE3 . TRP B 1 597 ? -11.204 -19.783 31.578 1.00 18.80 ? 617 TRP B CE3 1 ATOM 10419 C CZ2 . TRP B 1 597 ? -11.491 -18.605 29.014 1.00 18.79 ? 617 TRP B CZ2 1 ATOM 10420 C CZ3 . TRP B 1 597 ? -12.372 -19.110 31.211 1.00 18.65 ? 617 TRP B CZ3 1 ATOM 10421 C CH2 . TRP B 1 597 ? -12.501 -18.531 29.941 1.00 19.11 ? 617 TRP B CH2 1 ATOM 10422 N N . ALA B 1 598 ? -11.022 -22.931 31.675 1.00 21.46 ? 618 ALA B N 1 ATOM 10423 C CA . ALA B 1 598 ? -12.437 -23.029 32.069 1.00 21.38 ? 618 ALA B CA 1 ATOM 10424 C C . ALA B 1 598 ? -12.759 -24.379 32.664 1.00 21.44 ? 618 ALA B C 1 ATOM 10425 O O . ALA B 1 598 ? -13.907 -24.655 32.975 1.00 21.32 ? 618 ALA B O 1 ATOM 10426 C CB . ALA B 1 598 ? -13.366 -22.754 30.875 1.00 21.16 ? 618 ALA B CB 1 ATOM 10427 N N . ARG B 1 599 ? -11.753 -25.239 32.799 1.00 21.83 ? 619 ARG B N 1 ATOM 10428 C CA . ARG B 1 599 ? -11.892 -26.435 33.628 1.00 21.64 ? 619 ARG B CA 1 ATOM 10429 C C . ARG B 1 599 ? -11.876 -26.091 35.114 1.00 21.46 ? 619 ARG B C 1 ATOM 10430 O O . ARG B 1 599 ? -12.280 -26.903 35.939 1.00 21.90 ? 619 ARG B O 1 ATOM 10431 C CB . ARG B 1 599 ? -10.764 -27.416 33.351 1.00 21.62 ? 619 ARG B CB 1 ATOM 10432 C CG . ARG B 1 599 ? -10.776 -28.008 31.951 1.00 22.49 ? 619 ARG B CG 1 ATOM 10433 C CD . ARG B 1 599 ? -9.481 -28.772 31.667 1.00 22.44 ? 619 ARG B CD 1 ATOM 10434 N NE . ARG B 1 599 ? -9.367 -29.164 30.265 1.00 23.17 ? 619 ARG B NE 1 ATOM 10435 C CZ . ARG B 1 599 ? -8.413 -29.956 29.770 1.00 24.26 ? 619 ARG B CZ 1 ATOM 10436 N NH1 . ARG B 1 599 ? -7.473 -30.466 30.554 1.00 24.51 ? 619 ARG B NH1 1 ATOM 10437 N NH2 . ARG B 1 599 ? -8.404 -30.256 28.479 1.00 25.11 ? 619 ARG B NH2 1 ATOM 10438 N N . TYR B 1 600 ? -11.395 -24.907 35.466 1.00 21.11 ? 620 TYR B N 1 ATOM 10439 C CA . TYR B 1 600 ? -11.043 -24.636 36.859 1.00 20.93 ? 620 TYR B CA 1 ATOM 10440 C C . TYR B 1 600 ? -11.645 -23.320 37.366 1.00 20.94 ? 620 TYR B C 1 ATOM 10441 O O . TYR B 1 600 ? -11.232 -22.234 36.926 1.00 21.30 ? 620 TYR B O 1 ATOM 10442 C CB . TYR B 1 600 ? -9.520 -24.604 37.016 1.00 20.79 ? 620 TYR B CB 1 ATOM 10443 C CG . TYR B 1 600 ? -8.804 -25.830 36.493 1.00 20.39 ? 620 TYR B CG 1 ATOM 10444 C CD1 . TYR B 1 600 ? -8.107 -25.788 35.293 1.00 20.04 ? 620 TYR B CD1 1 ATOM 10445 C CD2 . TYR B 1 600 ? -8.811 -27.032 37.201 1.00 20.81 ? 620 TYR B CD2 1 ATOM 10446 C CE1 . TYR B 1 600 ? -7.443 -26.906 34.801 1.00 19.56 ? 620 TYR B CE1 1 ATOM 10447 C CE2 . TYR B 1 600 ? -8.150 -28.164 36.713 1.00 20.57 ? 620 TYR B CE2 1 ATOM 10448 C CZ . TYR B 1 600 ? -7.463 -28.082 35.507 1.00 20.11 ? 620 TYR B CZ 1 ATOM 10449 O OH . TYR B 1 600 ? -6.800 -29.170 34.999 1.00 20.58 ? 620 TYR B OH 1 ATOM 10450 N N . PRO B 1 601 ? -12.631 -23.404 38.282 1.00 21.03 ? 621 PRO B N 1 ATOM 10451 C CA . PRO B 1 601 ? -13.029 -22.178 38.980 1.00 20.90 ? 621 PRO B CA 1 ATOM 10452 C C . PRO B 1 601 ? -11.836 -21.520 39.676 1.00 20.84 ? 621 PRO B C 1 ATOM 10453 O O . PRO B 1 601 ? -11.745 -20.298 39.736 1.00 20.28 ? 621 PRO B O 1 ATOM 10454 C CB . PRO B 1 601 ? -14.055 -22.657 40.008 1.00 20.93 ? 621 PRO B CB 1 ATOM 10455 C CG . PRO B 1 601 ? -14.015 -24.178 39.977 1.00 21.21 ? 621 PRO B CG 1 ATOM 10456 C CD . PRO B 1 601 ? -13.493 -24.548 38.639 1.00 21.10 ? 621 PRO B CD 1 ATOM 10457 N N . LEU B 1 602 ? -10.930 -22.342 40.197 1.00 21.04 ? 622 LEU B N 1 ATOM 10458 C CA . LEU B 1 602 ? -9.708 -21.848 40.811 1.00 21.06 ? 622 LEU B CA 1 ATOM 10459 C C . LEU B 1 602 ? -8.576 -22.813 40.504 1.00 20.98 ? 622 LEU B C 1 ATOM 10460 O O . LEU B 1 602 ? -8.730 -24.025 40.648 1.00 21.23 ? 622 LEU B O 1 ATOM 10461 C CB . LEU B 1 602 ? -9.871 -21.693 42.329 1.00 20.99 ? 622 LEU B CB 1 ATOM 10462 C CG . LEU B 1 602 ? -8.583 -21.350 43.122 1.00 21.08 ? 622 LEU B CG 1 ATOM 10463 C CD1 . LEU B 1 602 ? -8.067 -19.962 42.762 1.00 17.45 ? 622 LEU B CD1 1 ATOM 10464 C CD2 . LEU B 1 602 ? -8.785 -21.483 44.644 1.00 19.87 ? 622 LEU B CD2 1 ATOM 10465 N N . ALA B 1 603 ? -7.450 -22.266 40.064 1.00 20.66 ? 623 ALA B N 1 ATOM 10466 C CA . ALA B 1 603 ? -6.204 -23.012 40.010 1.00 20.88 ? 623 ALA B CA 1 ATOM 10467 C C . ALA B 1 603 ? -5.088 -22.106 40.476 1.00 20.89 ? 623 ALA B C 1 ATOM 10468 O O . ALA B 1 603 ? -5.127 -20.894 40.292 1.00 21.04 ? 623 ALA B O 1 ATOM 10469 C CB . ALA B 1 603 ? -5.923 -23.536 38.602 1.00 20.72 ? 623 ALA B CB 1 ATOM 10470 N N . VAL B 1 604 ? -4.084 -22.705 41.088 1.00 21.44 ? 624 VAL B N 1 ATOM 10471 C CA . VAL B 1 604 ? -3.006 -21.943 41.666 1.00 21.94 ? 624 VAL B CA 1 ATOM 10472 C C . VAL B 1 604 ? -1.716 -22.394 41.007 1.00 22.35 ? 624 VAL B C 1 ATOM 10473 O O . VAL B 1 604 ? -1.434 -23.589 40.958 1.00 23.17 ? 624 VAL B O 1 ATOM 10474 C CB . VAL B 1 604 ? -2.961 -22.140 43.195 1.00 22.12 ? 624 VAL B CB 1 ATOM 10475 C CG1 . VAL B 1 604 ? -1.891 -21.234 43.835 1.00 21.51 ? 624 VAL B CG1 1 ATOM 10476 C CG2 . VAL B 1 604 ? -4.345 -21.858 43.803 1.00 21.38 ? 624 VAL B CG2 1 ATOM 10477 N N . THR B 1 605 ? -0.956 -21.443 40.472 1.00 22.66 ? 625 THR B N 1 ATOM 10478 C CA . THR B 1 605 ? 0.341 -21.752 39.865 1.00 22.82 ? 625 THR B CA 1 ATOM 10479 C C . THR B 1 605 ? 1.470 -20.992 40.534 1.00 23.31 ? 625 THR B C 1 ATOM 10480 O O . THR B 1 605 ? 1.271 -19.944 41.163 1.00 22.54 ? 625 THR B O 1 ATOM 10481 C CB . THR B 1 605 ? 0.396 -21.460 38.329 1.00 22.48 ? 625 THR B CB 1 ATOM 10482 O OG1 . THR B 1 605 ? 0.200 -20.060 38.076 1.00 21.20 ? 625 THR B OG1 1 ATOM 10483 C CG2 . THR B 1 605 ? -0.652 -22.268 37.594 1.00 22.56 ? 625 THR B CG2 1 ATOM 10484 N N . LYS B 1 606 ? 2.660 -21.563 40.412 1.00 24.39 ? 626 LYS B N 1 ATOM 10485 C CA . LYS B 1 606 ? 3.875 -20.878 40.786 1.00 25.54 ? 626 LYS B CA 1 ATOM 10486 C C . LYS B 1 606 ? 4.127 -19.849 39.692 1.00 26.07 ? 626 LYS B C 1 ATOM 10487 O O . LYS B 1 606 ? 4.009 -20.165 38.499 1.00 26.21 ? 626 LYS B O 1 ATOM 10488 C CB . LYS B 1 606 ? 5.027 -21.873 40.896 1.00 25.76 ? 626 LYS B CB 1 ATOM 10489 C CG . LYS B 1 606 ? 6.394 -21.257 41.117 1.00 27.12 ? 626 LYS B CG 1 ATOM 10490 C CD . LYS B 1 606 ? 7.362 -22.335 41.602 1.00 29.55 ? 626 LYS B CD 1 ATOM 10491 C CE . LYS B 1 606 ? 8.805 -21.926 41.420 1.00 32.03 ? 626 LYS B CE 1 ATOM 10492 N NZ . LYS B 1 606 ? 9.725 -23.046 41.789 1.00 34.48 ? 626 LYS B NZ 1 ATOM 10493 N N . TYR B 1 607 ? 4.437 -18.620 40.098 1.00 26.72 ? 627 TYR B N 1 ATOM 10494 C CA . TYR B 1 607 ? 4.706 -17.534 39.159 1.00 27.41 ? 627 TYR B CA 1 ATOM 10495 C C . TYR B 1 607 ? 5.792 -17.933 38.154 1.00 28.20 ? 627 TYR B C 1 ATOM 10496 O O . TYR B 1 607 ? 6.835 -18.471 38.544 1.00 27.87 ? 627 TYR B O 1 ATOM 10497 C CB . TYR B 1 607 ? 5.121 -16.254 39.903 1.00 27.42 ? 627 TYR B CB 1 ATOM 10498 C CG . TYR B 1 607 ? 5.348 -15.072 38.977 1.00 27.88 ? 627 TYR B CG 1 ATOM 10499 C CD1 . TYR B 1 607 ? 6.570 -14.896 38.313 1.00 27.92 ? 627 TYR B CD1 1 ATOM 10500 C CD2 . TYR B 1 607 ? 4.340 -14.138 38.752 1.00 28.04 ? 627 TYR B CD2 1 ATOM 10501 C CE1 . TYR B 1 607 ? 6.771 -13.828 37.445 1.00 27.50 ? 627 TYR B CE1 1 ATOM 10502 C CE2 . TYR B 1 607 ? 4.536 -13.064 37.899 1.00 28.06 ? 627 TYR B CE2 1 ATOM 10503 C CZ . TYR B 1 607 ? 5.744 -12.918 37.239 1.00 28.68 ? 627 TYR B CZ 1 ATOM 10504 O OH . TYR B 1 607 ? 5.914 -11.844 36.391 1.00 28.86 ? 627 TYR B OH 1 ATOM 10505 N N . ARG B 1 608 ? 5.519 -17.672 36.872 1.00 28.86 ? 628 ARG B N 1 ATOM 10506 C CA . ARG B 1 608 ? 6.479 -17.830 35.773 1.00 29.51 ? 628 ARG B CA 1 ATOM 10507 C C . ARG B 1 608 ? 6.272 -16.744 34.706 1.00 29.30 ? 628 ARG B C 1 ATOM 10508 O O . ARG B 1 608 ? 5.137 -16.490 34.280 1.00 27.99 ? 628 ARG B O 1 ATOM 10509 C CB . ARG B 1 608 ? 6.310 -19.195 35.102 1.00 30.25 ? 628 ARG B CB 1 ATOM 10510 C CG . ARG B 1 608 ? 6.783 -20.365 35.937 1.00 32.91 ? 628 ARG B CG 1 ATOM 10511 C CD . ARG B 1 608 ? 6.649 -21.686 35.197 1.00 36.32 ? 628 ARG B CD 1 ATOM 10512 N NE . ARG B 1 608 ? 7.381 -22.741 35.903 1.00 40.05 ? 628 ARG B NE 1 ATOM 10513 C CZ . ARG B 1 608 ? 8.543 -23.279 35.511 1.00 42.37 ? 628 ARG B CZ 1 ATOM 10514 N NH1 . ARG B 1 608 ? 9.150 -22.903 34.382 1.00 43.37 ? 628 ARG B NH1 1 ATOM 10515 N NH2 . ARG B 1 608 ? 9.109 -24.219 36.260 1.00 42.68 ? 628 ARG B NH2 1 ATOM 10516 N N . GLU B 1 609 ? 7.377 -16.143 34.254 1.00 29.10 ? 629 GLU B N 1 ATOM 10517 C CA . GLU B 1 609 ? 7.344 -15.154 33.180 1.00 29.42 ? 629 GLU B CA 1 ATOM 10518 C C . GLU B 1 609 ? 6.835 -15.739 31.864 1.00 29.08 ? 629 GLU B C 1 ATOM 10519 O O . GLU B 1 609 ? 6.344 -15.013 31.015 1.00 29.15 ? 629 GLU B O 1 ATOM 10520 C CB . GLU B 1 609 ? 8.730 -14.519 32.961 1.00 29.76 ? 629 GLU B CB 1 ATOM 10521 C CG . GLU B 1 609 ? 9.184 -13.557 34.083 1.00 30.56 ? 629 GLU B CG 1 ATOM 10522 C CD . GLU B 1 609 ? 8.404 -12.234 34.141 1.00 31.83 ? 629 GLU B CD 1 ATOM 10523 O OE1 . GLU B 1 609 ? 7.917 -11.751 33.094 1.00 31.44 ? 629 GLU B OE1 1 ATOM 10524 O OE2 . GLU B 1 609 ? 8.293 -11.662 35.251 1.00 33.14 ? 629 GLU B OE2 1 ATOM 10525 N N . SER B 1 610 ? 6.941 -17.051 31.696 1.00 28.94 ? 630 SER B N 1 ATOM 10526 C CA . SER B 1 610 ? 6.435 -17.700 30.496 1.00 28.93 ? 630 SER B CA 1 ATOM 10527 C C . SER B 1 610 ? 4.927 -17.983 30.573 1.00 28.89 ? 630 SER B C 1 ATOM 10528 O O . SER B 1 610 ? 4.365 -18.529 29.631 1.00 29.08 ? 630 SER B O 1 ATOM 10529 C CB . SER B 1 610 ? 7.174 -19.004 30.273 1.00 28.67 ? 630 SER B CB 1 ATOM 10530 O OG . SER B 1 610 ? 6.945 -19.870 31.362 1.00 29.38 ? 630 SER B OG 1 ATOM 10531 N N . GLU B 1 611 ? 4.288 -17.616 31.685 1.00 28.54 ? 631 GLU B N 1 ATOM 10532 C CA . GLU B 1 611 ? 2.879 -17.910 31.917 1.00 28.23 ? 631 GLU B CA 1 ATOM 10533 C C . GLU B 1 611 ? 2.136 -16.675 32.433 1.00 27.68 ? 631 GLU B C 1 ATOM 10534 O O . GLU B 1 611 ? 1.354 -16.769 33.373 1.00 27.61 ? 631 GLU B O 1 ATOM 10535 C CB . GLU B 1 611 ? 2.752 -19.050 32.934 1.00 28.34 ? 631 GLU B CB 1 ATOM 10536 C CG . GLU B 1 611 ? 3.505 -20.344 32.566 1.00 29.41 ? 631 GLU B CG 1 ATOM 10537 C CD . GLU B 1 611 ? 3.423 -21.407 33.654 1.00 30.66 ? 631 GLU B CD 1 ATOM 10538 O OE1 . GLU B 1 611 ? 3.081 -21.076 34.817 1.00 31.54 ? 631 GLU B OE1 1 ATOM 10539 O OE2 . GLU B 1 611 ? 3.714 -22.581 33.351 1.00 31.46 ? 631 GLU B OE2 1 ATOM 10540 N N . LEU B 1 612 ? 2.374 -15.517 31.824 1.00 26.86 ? 632 LEU B N 1 ATOM 10541 C CA . LEU B 1 612 ? 1.727 -14.285 32.280 1.00 26.59 ? 632 LEU B CA 1 ATOM 10542 C C . LEU B 1 612 ? 0.256 -14.204 31.852 1.00 26.01 ? 632 LEU B C 1 ATOM 10543 O O . LEU B 1 612 ? -0.530 -13.492 32.473 1.00 25.54 ? 632 LEU B O 1 ATOM 10544 C CB . LEU B 1 612 ? 2.464 -13.054 31.759 1.00 26.57 ? 632 LEU B CB 1 ATOM 10545 C CG . LEU B 1 612 ? 3.959 -12.975 32.072 1.00 27.65 ? 632 LEU B CG 1 ATOM 10546 C CD1 . LEU B 1 612 ? 4.502 -11.665 31.517 1.00 27.96 ? 632 LEU B CD1 1 ATOM 10547 C CD2 . LEU B 1 612 ? 4.235 -13.114 33.573 1.00 27.89 ? 632 LEU B CD2 1 ATOM 10548 N N . CYS B 1 613 ? -0.102 -14.940 30.803 1.00 25.75 ? 633 CYS B N 1 ATOM 10549 C CA . CYS B 1 613 ? -1.437 -14.877 30.212 1.00 25.94 ? 633 CYS B CA 1 ATOM 10550 C C . CYS B 1 613 ? -2.024 -16.257 29.955 1.00 24.80 ? 633 CYS B C 1 ATOM 10551 O O . CYS B 1 613 ? -1.317 -17.176 29.556 1.00 24.95 ? 633 CYS B O 1 ATOM 10552 C CB . CYS B 1 613 ? -1.380 -14.099 28.892 1.00 25.93 ? 633 CYS B CB 1 ATOM 10553 S SG . CYS B 1 613 ? -0.861 -12.394 29.094 1.00 30.35 ? 633 CYS B SG 1 ATOM 10554 N N . SER B 1 614 ? -3.331 -16.388 30.155 1.00 23.87 ? 634 SER B N 1 ATOM 10555 C CA . SER B 1 614 ? -4.011 -17.646 29.906 1.00 22.98 ? 634 SER B CA 1 ATOM 10556 C C . SER B 1 614 ? -4.584 -17.714 28.491 1.00 22.27 ? 634 SER B C 1 ATOM 10557 O O . SER B 1 614 ? -5.003 -18.775 28.055 1.00 22.13 ? 634 SER B O 1 ATOM 10558 C CB . SER B 1 614 ? -5.118 -17.871 30.942 1.00 23.05 ? 634 SER B CB 1 ATOM 10559 O OG . SER B 1 614 ? -5.954 -16.740 31.056 1.00 23.13 ? 634 SER B OG 1 ATOM 10560 N N . SER B 1 615 ? -4.616 -16.588 27.787 1.00 21.59 ? 635 SER B N 1 ATOM 10561 C CA . SER B 1 615 ? -5.133 -16.554 26.414 1.00 21.23 ? 635 SER B CA 1 ATOM 10562 C C . SER B 1 615 ? -4.264 -15.654 25.545 1.00 20.74 ? 635 SER B C 1 ATOM 10563 O O . SER B 1 615 ? -3.165 -15.273 25.955 1.00 20.95 ? 635 SER B O 1 ATOM 10564 C CB . SER B 1 615 ? -6.589 -16.095 26.402 1.00 21.28 ? 635 SER B CB 1 ATOM 10565 O OG . SER B 1 615 ? -7.228 -16.521 25.215 1.00 22.26 ? 635 SER B OG 1 ATOM 10566 N N . SER B 1 616 ? -4.749 -15.338 24.349 1.00 20.19 ? 636 SER B N 1 ATOM 10567 C CA . SER B 1 616 ? -4.060 -14.449 23.410 1.00 20.16 ? 636 SER B CA 1 ATOM 10568 C C . SER B 1 616 ? -5.058 -14.016 22.332 1.00 19.69 ? 636 SER B C 1 ATOM 10569 O O . SER B 1 616 ? -6.107 -14.627 22.177 1.00 19.12 ? 636 SER B O 1 ATOM 10570 C CB . SER B 1 616 ? -2.882 -15.177 22.739 1.00 20.11 ? 636 SER B CB 1 ATOM 10571 O OG . SER B 1 616 ? -3.336 -16.027 21.676 1.00 20.19 ? 636 SER B OG 1 ATOM 10572 N N . ILE B 1 617 ? -4.709 -12.987 21.568 1.00 20.12 ? 637 ILE B N 1 ATOM 10573 C CA . ILE B 1 617 ? -5.535 -12.547 20.416 1.00 20.44 ? 637 ILE B CA 1 ATOM 10574 C C . ILE B 1 617 ? -5.667 -13.583 19.293 1.00 20.67 ? 637 ILE B C 1 ATOM 10575 O O . ILE B 1 617 ? -6.485 -13.409 18.387 1.00 21.03 ? 637 ILE B O 1 ATOM 10576 C CB . ILE B 1 617 ? -5.005 -11.240 19.775 1.00 20.29 ? 637 ILE B CB 1 ATOM 10577 C CG1 . ILE B 1 617 ? -3.597 -11.451 19.193 1.00 20.09 ? 637 ILE B CG1 1 ATOM 10578 C CG2 . ILE B 1 617 ? -5.042 -10.110 20.802 1.00 20.44 ? 637 ILE B CG2 1 ATOM 10579 C CD1 . ILE B 1 617 ? -3.011 -10.220 18.513 1.00 20.60 ? 637 ILE B CD1 1 ATOM 10580 N N . TYR B 1 618 ? -4.855 -14.638 19.350 1.00 20.93 ? 638 TYR B N 1 ATOM 10581 C CA . TYR B 1 618 ? -4.841 -15.691 18.340 1.00 21.13 ? 638 TYR B CA 1 ATOM 10582 C C . TYR B 1 618 ? -5.790 -16.850 18.643 1.00 20.88 ? 638 TYR B C 1 ATOM 10583 O O . TYR B 1 618 ? -6.166 -17.582 17.732 1.00 20.89 ? 638 TYR B O 1 ATOM 10584 C CB . TYR B 1 618 ? -3.414 -16.238 18.180 1.00 21.32 ? 638 TYR B CB 1 ATOM 10585 C CG . TYR B 1 618 ? -2.405 -15.151 17.949 1.00 21.85 ? 638 TYR B CG 1 ATOM 10586 C CD1 . TYR B 1 618 ? -1.473 -14.826 18.922 1.00 22.83 ? 638 TYR B CD1 1 ATOM 10587 C CD2 . TYR B 1 618 ? -2.413 -14.415 16.770 1.00 23.94 ? 638 TYR B CD2 1 ATOM 10588 C CE1 . TYR B 1 618 ? -0.558 -13.810 18.724 1.00 23.90 ? 638 TYR B CE1 1 ATOM 10589 C CE2 . TYR B 1 618 ? -1.501 -13.395 16.553 1.00 23.73 ? 638 TYR B CE2 1 ATOM 10590 C CZ . TYR B 1 618 ? -0.577 -13.093 17.536 1.00 24.48 ? 638 TYR B CZ 1 ATOM 10591 O OH . TYR B 1 618 ? 0.325 -12.079 17.327 1.00 25.57 ? 638 TYR B OH 1 ATOM 10592 N N . HIS B 1 619 ? -6.167 -17.025 19.906 1.00 20.56 ? 639 HIS B N 1 ATOM 10593 C CA . HIS B 1 619 ? -7.009 -18.164 20.295 1.00 20.80 ? 639 HIS B CA 1 ATOM 10594 C C . HIS B 1 619 ? -8.331 -18.252 19.535 1.00 20.69 ? 639 HIS B C 1 ATOM 10595 O O . HIS B 1 619 ? -8.770 -19.341 19.214 1.00 20.77 ? 639 HIS B O 1 ATOM 10596 C CB . HIS B 1 619 ? -7.297 -18.156 21.802 1.00 21.21 ? 639 HIS B CB 1 ATOM 10597 C CG . HIS B 1 619 ? -6.159 -18.661 22.638 1.00 20.91 ? 639 HIS B CG 1 ATOM 10598 N ND1 . HIS B 1 619 ? -4.913 -18.075 22.626 1.00 21.15 ? 639 HIS B ND1 1 ATOM 10599 C CD2 . HIS B 1 619 ? -6.086 -19.690 23.516 1.00 20.12 ? 639 HIS B CD2 1 ATOM 10600 C CE1 . HIS B 1 619 ? -4.115 -18.729 23.455 1.00 22.09 ? 639 HIS B CE1 1 ATOM 10601 N NE2 . HIS B 1 619 ? -4.803 -19.712 24.010 1.00 20.91 ? 639 HIS B NE2 1 ATOM 10602 N N . GLN B 1 620 ? -8.964 -17.117 19.256 1.00 20.70 ? 640 GLN B N 1 ATOM 10603 C CA . GLN B 1 620 ? -10.264 -17.121 18.568 1.00 20.89 ? 640 GLN B CA 1 ATOM 10604 C C . GLN B 1 620 ? -10.216 -17.855 17.229 1.00 21.07 ? 640 GLN B C 1 ATOM 10605 O O . GLN B 1 620 ? -11.116 -18.625 16.908 1.00 20.80 ? 640 GLN B O 1 ATOM 10606 C CB . GLN B 1 620 ? -10.746 -15.684 18.350 1.00 20.78 ? 640 GLN B CB 1 ATOM 10607 C CG . GLN B 1 620 ? -12.000 -15.530 17.501 1.00 20.80 ? 640 GLN B CG 1 ATOM 10608 C CD . GLN B 1 620 ? -13.238 -16.045 18.191 1.00 19.96 ? 640 GLN B CD 1 ATOM 10609 O OE1 . GLN B 1 620 ? -14.030 -15.263 18.720 1.00 19.45 ? 640 GLN B OE1 1 ATOM 10610 N NE2 . GLN B 1 620 ? -13.416 -17.362 18.197 1.00 20.97 ? 640 GLN B NE2 1 ATOM 10611 N N . ASN B 1 621 ? -9.172 -17.599 16.441 1.00 21.63 ? 641 ASN B N 1 ATOM 10612 C CA . ASN B 1 621 ? -9.120 -18.101 15.070 1.00 21.84 ? 641 ASN B CA 1 ATOM 10613 C C . ASN B 1 621 ? -8.238 -19.352 14.894 1.00 22.11 ? 641 ASN B C 1 ATOM 10614 O O . ASN B 1 621 ? -8.218 -19.949 13.817 1.00 22.04 ? 641 ASN B O 1 ATOM 10615 C CB . ASN B 1 621 ? -8.735 -16.971 14.097 1.00 21.80 ? 641 ASN B CB 1 ATOM 10616 C CG . ASN B 1 621 ? -9.888 -15.997 13.833 1.00 21.93 ? 641 ASN B CG 1 ATOM 10617 O OD1 . ASN B 1 621 ? -11.053 -16.301 14.104 1.00 21.84 ? 641 ASN B OD1 1 ATOM 10618 N ND2 . ASN B 1 621 ? -9.561 -14.818 13.302 1.00 21.24 ? 641 ASN B ND2 1 ATOM 10619 N N . ASP B 1 622 ? -7.523 -19.753 15.944 1.00 22.37 ? 642 ASP B N 1 ATOM 10620 C CA . ASP B 1 622 ? -6.975 -21.118 16.007 1.00 22.44 ? 642 ASP B CA 1 ATOM 10621 C C . ASP B 1 622 ? -7.147 -21.703 17.411 1.00 22.33 ? 642 ASP B C 1 ATOM 10622 O O . ASP B 1 622 ? -6.167 -21.847 18.155 1.00 22.57 ? 642 ASP B O 1 ATOM 10623 C CB . ASP B 1 622 ? -5.496 -21.178 15.567 1.00 22.20 ? 642 ASP B CB 1 ATOM 10624 C CG . ASP B 1 622 ? -5.020 -22.610 15.301 1.00 22.94 ? 642 ASP B CG 1 ATOM 10625 O OD1 . ASP B 1 622 ? -5.788 -23.572 15.560 1.00 22.37 ? 642 ASP B OD1 1 ATOM 10626 O OD2 . ASP B 1 622 ? -3.877 -22.781 14.813 1.00 22.78 ? 642 ASP B OD2 1 ATOM 10627 N N . PRO B 1 623 ? -8.392 -22.064 17.773 1.00 22.20 ? 643 PRO B N 1 ATOM 10628 C CA . PRO B 1 623 ? -8.643 -22.665 19.081 1.00 22.29 ? 643 PRO B CA 1 ATOM 10629 C C . PRO B 1 623 ? -8.172 -24.122 19.162 1.00 22.39 ? 643 PRO B C 1 ATOM 10630 O O . PRO B 1 623 ? -8.092 -24.687 20.254 1.00 22.31 ? 643 PRO B O 1 ATOM 10631 C CB . PRO B 1 623 ? -10.170 -22.571 19.221 1.00 22.20 ? 643 PRO B CB 1 ATOM 10632 C CG . PRO B 1 623 ? -10.664 -22.624 17.828 1.00 22.82 ? 643 PRO B CG 1 ATOM 10633 C CD . PRO B 1 623 ? -9.635 -21.901 17.000 1.00 22.10 ? 643 PRO B CD 1 ATOM 10634 N N . TRP B 1 624 ? -7.873 -24.724 18.012 1.00 22.79 ? 644 TRP B N 1 ATOM 10635 C CA . TRP B 1 624 ? -7.434 -26.111 17.969 1.00 23.21 ? 644 TRP B CA 1 ATOM 10636 C C . TRP B 1 624 ? -5.956 -26.237 18.347 1.00 23.26 ? 644 TRP B C 1 ATOM 10637 O O . TRP B 1 624 ? -5.567 -27.217 18.971 1.00 23.77 ? 644 TRP B O 1 ATOM 10638 C CB . TRP B 1 624 ? -7.682 -26.719 16.585 1.00 23.22 ? 644 TRP B CB 1 ATOM 10639 C CG . TRP B 1 624 ? -9.099 -26.609 16.142 1.00 23.31 ? 644 TRP B CG 1 ATOM 10640 C CD1 . TRP B 1 624 ? -10.132 -27.430 16.486 1.00 23.48 ? 644 TRP B CD1 1 ATOM 10641 C CD2 . TRP B 1 624 ? -9.650 -25.618 15.262 1.00 23.33 ? 644 TRP B CD2 1 ATOM 10642 N NE1 . TRP B 1 624 ? -11.296 -27.007 15.881 1.00 24.73 ? 644 TRP B NE1 1 ATOM 10643 C CE2 . TRP B 1 624 ? -11.028 -25.897 15.127 1.00 23.98 ? 644 TRP B CE2 1 ATOM 10644 C CE3 . TRP B 1 624 ? -9.117 -24.515 14.587 1.00 22.38 ? 644 TRP B CE3 1 ATOM 10645 C CZ2 . TRP B 1 624 ? -11.873 -25.118 14.340 1.00 23.88 ? 644 TRP B CZ2 1 ATOM 10646 C CZ3 . TRP B 1 624 ? -9.955 -23.752 13.797 1.00 21.58 ? 644 TRP B CZ3 1 ATOM 10647 C CH2 . TRP B 1 624 ? -11.314 -24.055 13.678 1.00 22.29 ? 644 TRP B CH2 1 ATOM 10648 N N . ASP B 1 625 ? -5.144 -25.249 17.989 1.00 23.48 ? 645 ASP B N 1 ATOM 10649 C CA . ASP B 1 625 ? -3.706 -25.306 18.268 1.00 23.86 ? 645 ASP B CA 1 ATOM 10650 C C . ASP B 1 625 ? -3.167 -23.939 18.713 1.00 23.47 ? 645 ASP B C 1 ATOM 10651 O O . ASP B 1 625 ? -2.316 -23.350 18.049 1.00 23.91 ? 645 ASP B O 1 ATOM 10652 C CB . ASP B 1 625 ? -2.972 -25.829 17.024 1.00 24.07 ? 645 ASP B CB 1 ATOM 10653 C CG . ASP B 1 625 ? -1.504 -26.185 17.297 1.00 25.75 ? 645 ASP B CG 1 ATOM 10654 O OD1 . ASP B 1 625 ? -1.055 -26.119 18.462 1.00 27.03 ? 645 ASP B OD1 1 ATOM 10655 O OD2 . ASP B 1 625 ? -0.797 -26.518 16.328 1.00 27.00 ? 645 ASP B OD2 1 ATOM 10656 N N . PRO B 1 626 ? -3.668 -23.425 19.849 1.00 23.01 ? 646 PRO B N 1 ATOM 10657 C CA . PRO B 1 626 ? -3.300 -22.080 20.290 1.00 22.84 ? 646 PRO B CA 1 ATOM 10658 C C . PRO B 1 626 ? -1.906 -21.998 20.915 1.00 22.90 ? 646 PRO B C 1 ATOM 10659 O O . PRO B 1 626 ? -1.374 -23.022 21.349 1.00 22.76 ? 646 PRO B O 1 ATOM 10660 C CB . PRO B 1 626 ? -4.348 -21.778 21.356 1.00 22.77 ? 646 PRO B CB 1 ATOM 10661 C CG . PRO B 1 626 ? -4.636 -23.116 21.950 1.00 22.76 ? 646 PRO B CG 1 ATOM 10662 C CD . PRO B 1 626 ? -4.611 -24.063 20.784 1.00 22.85 ? 646 PRO B CD 1 ATOM 10663 N N . PRO B 1 627 ? -1.340 -20.775 20.999 1.00 22.91 ? 647 PRO B N 1 ATOM 10664 C CA . PRO B 1 627 ? -0.007 -20.563 21.544 1.00 22.84 ? 647 PRO B CA 1 ATOM 10665 C C . PRO B 1 627 ? 0.067 -20.650 23.065 1.00 23.32 ? 647 PRO B C 1 ATOM 10666 O O . PRO B 1 627 ? 1.168 -20.675 23.609 1.00 23.16 ? 647 PRO B O 1 ATOM 10667 C CB . PRO B 1 627 ? 0.344 -19.146 21.083 1.00 22.67 ? 647 PRO B CB 1 ATOM 10668 C CG . PRO B 1 627 ? -0.948 -18.466 20.943 1.00 23.22 ? 647 PRO B CG 1 ATOM 10669 C CD . PRO B 1 627 ? -1.930 -19.518 20.503 1.00 22.85 ? 647 PRO B CD 1 ATOM 10670 N N . VAL B 1 628 ? -1.077 -20.672 23.750 1.00 23.30 ? 648 VAL B N 1 ATOM 10671 C CA . VAL B 1 628 ? -1.083 -20.821 25.196 1.00 23.35 ? 648 VAL B CA 1 ATOM 10672 C C . VAL B 1 628 ? -2.172 -21.810 25.569 1.00 23.44 ? 648 VAL B C 1 ATOM 10673 O O . VAL B 1 628 ? -3.340 -21.603 25.234 1.00 23.03 ? 648 VAL B O 1 ATOM 10674 C CB . VAL B 1 628 ? -1.324 -19.471 25.927 1.00 23.59 ? 648 VAL B CB 1 ATOM 10675 C CG1 . VAL B 1 628 ? -1.344 -19.673 27.443 1.00 23.79 ? 648 VAL B CG1 1 ATOM 10676 C CG2 . VAL B 1 628 ? -0.273 -18.442 25.548 1.00 23.28 ? 648 VAL B CG2 1 ATOM 10677 N N . VAL B 1 629 ? -1.773 -22.889 26.238 1.00 23.35 ? 649 VAL B N 1 ATOM 10678 C CA . VAL B 1 629 ? -2.698 -23.883 26.753 1.00 23.33 ? 649 VAL B CA 1 ATOM 10679 C C . VAL B 1 629 ? -2.584 -23.907 28.275 1.00 23.71 ? 649 VAL B C 1 ATOM 10680 O O . VAL B 1 629 ? -1.582 -24.387 28.822 1.00 23.45 ? 649 VAL B O 1 ATOM 10681 C CB . VAL B 1 629 ? -2.391 -25.267 26.181 1.00 23.37 ? 649 VAL B CB 1 ATOM 10682 C CG1 . VAL B 1 629 ? -3.302 -26.318 26.806 1.00 22.76 ? 649 VAL B CG1 1 ATOM 10683 C CG2 . VAL B 1 629 ? -2.519 -25.245 24.648 1.00 22.77 ? 649 VAL B CG2 1 ATOM 10684 N N . PHE B 1 630 ? -3.609 -23.387 28.955 1.00 23.42 ? 650 PHE B N 1 ATOM 10685 C CA . PHE B 1 630 ? -3.534 -23.195 30.403 1.00 23.48 ? 650 PHE B CA 1 ATOM 10686 C C . PHE B 1 630 ? -3.177 -24.476 31.162 1.00 23.79 ? 650 PHE B C 1 ATOM 10687 O O . PHE B 1 630 ? -2.384 -24.428 32.091 1.00 23.73 ? 650 PHE B O 1 ATOM 10688 C CB . PHE B 1 630 ? -4.831 -22.618 30.975 1.00 23.41 ? 650 PHE B CB 1 ATOM 10689 C CG . PHE B 1 630 ? -4.767 -22.420 32.442 1.00 22.92 ? 650 PHE B CG 1 ATOM 10690 C CD1 . PHE B 1 630 ? -4.207 -21.272 32.965 1.00 23.58 ? 650 PHE B CD1 1 ATOM 10691 C CD2 . PHE B 1 630 ? -5.187 -23.414 33.308 1.00 22.26 ? 650 PHE B CD2 1 ATOM 10692 C CE1 . PHE B 1 630 ? -4.110 -21.096 34.325 1.00 23.64 ? 650 PHE B CE1 1 ATOM 10693 C CE2 . PHE B 1 630 ? -5.092 -23.241 34.671 1.00 23.02 ? 650 PHE B CE2 1 ATOM 10694 C CZ . PHE B 1 630 ? -4.555 -22.081 35.181 1.00 22.86 ? 650 PHE B CZ 1 ATOM 10695 N N . GLU B 1 631 ? -3.763 -25.601 30.762 1.00 24.21 ? 651 GLU B N 1 ATOM 10696 C CA . GLU B 1 631 ? -3.469 -26.916 31.356 1.00 25.42 ? 651 GLU B CA 1 ATOM 10697 C C . GLU B 1 631 ? -1.965 -27.228 31.457 1.00 25.97 ? 651 GLU B C 1 ATOM 10698 O O . GLU B 1 631 ? -1.526 -27.864 32.422 1.00 26.03 ? 651 GLU B O 1 ATOM 10699 C CB . GLU B 1 631 ? -4.156 -28.025 30.542 1.00 25.54 ? 651 GLU B CB 1 ATOM 10700 C CG . GLU B 1 631 ? -4.049 -29.452 31.128 1.00 26.45 ? 651 GLU B CG 1 ATOM 10701 C CD . GLU B 1 631 ? -4.830 -29.641 32.426 1.00 27.84 ? 651 GLU B CD 1 ATOM 10702 O OE1 . GLU B 1 631 ? -5.761 -28.848 32.691 1.00 27.31 ? 651 GLU B OE1 1 ATOM 10703 O OE2 . GLU B 1 631 ? -4.516 -30.595 33.177 1.00 27.46 ? 651 GLU B OE2 1 ATOM 10704 N N . GLN B 1 632 ? -1.193 -26.796 30.458 1.00 26.50 ? 652 GLN B N 1 ATOM 10705 C CA . GLN B 1 632 ? 0.248 -27.067 30.425 1.00 27.31 ? 652 GLN B CA 1 ATOM 10706 C C . GLN B 1 632 ? 0.965 -26.357 31.568 1.00 27.16 ? 652 GLN B C 1 ATOM 10707 O O . GLN B 1 632 ? 2.014 -26.808 32.004 1.00 27.17 ? 652 GLN B O 1 ATOM 10708 C CB . GLN B 1 632 ? 0.864 -26.708 29.056 1.00 27.39 ? 652 GLN B CB 1 ATOM 10709 C CG . GLN B 1 632 ? 0.257 -27.566 27.925 1.00 29.44 ? 652 GLN B CG 1 ATOM 10710 C CD . GLN B 1 632 ? 0.685 -27.183 26.503 1.00 31.90 ? 652 GLN B CD 1 ATOM 10711 O OE1 . GLN B 1 632 ? 1.310 -26.141 26.262 1.00 34.54 ? 652 GLN B OE1 1 ATOM 10712 N NE2 . GLN B 1 632 ? 0.331 -28.040 25.548 1.00 32.63 ? 652 GLN B NE2 1 ATOM 10713 N N . PHE B 1 633 ? 0.383 -25.267 32.071 1.00 27.52 ? 653 PHE B N 1 ATOM 10714 C CA . PHE B 1 633 ? 0.920 -24.592 33.257 1.00 27.72 ? 653 PHE B CA 1 ATOM 10715 C C . PHE B 1 633 ? 0.996 -25.547 34.460 1.00 27.69 ? 653 PHE B C 1 ATOM 10716 O O . PHE B 1 633 ? 1.878 -25.404 35.303 1.00 27.48 ? 653 PHE B O 1 ATOM 10717 C CB . PHE B 1 633 ? 0.057 -23.388 33.659 1.00 27.99 ? 653 PHE B CB 1 ATOM 10718 C CG . PHE B 1 633 ? 0.068 -22.228 32.681 1.00 28.50 ? 653 PHE B CG 1 ATOM 10719 C CD1 . PHE B 1 633 ? 0.796 -22.262 31.489 1.00 29.04 ? 653 PHE B CD1 1 ATOM 10720 C CD2 . PHE B 1 633 ? -0.697 -21.100 32.958 1.00 28.91 ? 653 PHE B CD2 1 ATOM 10721 C CE1 . PHE B 1 633 ? 0.774 -21.188 30.622 1.00 29.45 ? 653 PHE B CE1 1 ATOM 10722 C CE2 . PHE B 1 633 ? -0.728 -20.021 32.086 1.00 29.91 ? 653 PHE B CE2 1 ATOM 10723 C CZ . PHE B 1 633 ? 0.007 -20.063 30.919 1.00 30.00 ? 653 PHE B CZ 1 ATOM 10724 N N . LEU B 1 634 ? 0.062 -26.501 34.537 1.00 27.80 ? 654 LEU B N 1 ATOM 10725 C CA . LEU B 1 634 ? -0.008 -27.465 35.639 1.00 27.78 ? 654 LEU B CA 1 ATOM 10726 C C . LEU B 1 634 ? 0.816 -28.745 35.420 1.00 28.41 ? 654 LEU B C 1 ATOM 10727 O O . LEU B 1 634 ? 0.939 -29.551 36.342 1.00 28.30 ? 654 LEU B O 1 ATOM 10728 C CB . LEU B 1 634 ? -1.469 -27.878 35.878 1.00 27.66 ? 654 LEU B CB 1 ATOM 10729 C CG . LEU B 1 634 ? -2.488 -26.756 36.091 1.00 27.34 ? 654 LEU B CG 1 ATOM 10730 C CD1 . LEU B 1 634 ? -3.928 -27.298 36.085 1.00 26.40 ? 654 LEU B CD1 1 ATOM 10731 C CD2 . LEU B 1 634 ? -2.189 -26.009 37.381 1.00 26.45 ? 654 LEU B CD2 1 ATOM 10732 N N . HIS B 1 635 ? 1.368 -28.939 34.220 1.00 28.94 ? 655 HIS B N 1 ATOM 10733 C CA A HIS B 1 635 ? 2.022 -30.203 33.869 0.50 29.12 ? 655 HIS B CA 1 ATOM 10734 C CA B HIS B 1 635 ? 2.029 -30.206 33.865 0.50 29.10 ? 655 HIS B CA 1 ATOM 10735 C C . HIS B 1 635 ? 3.229 -30.515 34.758 1.00 29.25 ? 655 HIS B C 1 ATOM 10736 O O . HIS B 1 635 ? 3.415 -31.659 35.178 1.00 29.22 ? 655 HIS B O 1 ATOM 10737 C CB A HIS B 1 635 ? 2.429 -30.202 32.390 0.50 29.22 ? 655 HIS B CB 1 ATOM 10738 C CB B HIS B 1 635 ? 2.472 -30.217 32.393 0.50 29.21 ? 655 HIS B CB 1 ATOM 10739 C CG A HIS B 1 635 ? 1.287 -30.458 31.453 0.50 29.34 ? 655 HIS B CG 1 ATOM 10740 C CG B HIS B 1 635 ? 3.061 -31.523 31.947 0.50 29.11 ? 655 HIS B CG 1 ATOM 10741 N ND1 A HIS B 1 635 ? 1.455 -30.593 30.091 0.50 29.08 ? 655 HIS B ND1 1 ATOM 10742 N ND1 B HIS B 1 635 ? 4.418 -31.716 31.795 0.50 29.50 ? 655 HIS B ND1 1 ATOM 10743 C CD2 A HIS B 1 635 ? -0.036 -30.628 31.687 0.50 28.99 ? 655 HIS B CD2 1 ATOM 10744 C CD2 B HIS B 1 635 ? 2.477 -32.704 31.632 0.50 29.37 ? 655 HIS B CD2 1 ATOM 10745 C CE1 A HIS B 1 635 ? 0.283 -30.822 29.526 0.50 28.81 ? 655 HIS B CE1 1 ATOM 10746 C CE1 B HIS B 1 635 ? 4.645 -32.958 31.407 0.50 29.35 ? 655 HIS B CE1 1 ATOM 10747 N NE2 A HIS B 1 635 ? -0.637 -30.851 30.472 0.50 28.50 ? 655 HIS B NE2 1 ATOM 10748 N NE2 B HIS B 1 635 ? 3.483 -33.579 31.300 0.50 29.75 ? 655 HIS B NE2 1 ATOM 10749 N N . ASN B 1 636 ? 4.050 -29.507 35.047 1.00 29.26 ? 656 ASN B N 1 ATOM 10750 C CA . ASN B 1 636 ? 5.225 -29.743 35.904 1.00 29.53 ? 656 ASN B CA 1 ATOM 10751 C C . ASN B 1 636 ? 4.864 -29.917 37.385 1.00 29.55 ? 656 ASN B C 1 ATOM 10752 O O . ASN B 1 636 ? 5.723 -30.262 38.186 1.00 29.94 ? 656 ASN B O 1 ATOM 10753 C CB . ASN B 1 636 ? 6.299 -28.666 35.721 1.00 29.48 ? 656 ASN B CB 1 ATOM 10754 C CG . ASN B 1 636 ? 5.754 -27.256 35.856 1.00 30.84 ? 656 ASN B CG 1 ATOM 10755 O OD1 . ASN B 1 636 ? 4.565 -27.055 36.162 1.00 31.97 ? 656 ASN B OD1 1 ATOM 10756 N ND2 . ASN B 1 636 ? 6.610 -26.260 35.600 1.00 30.56 ? 656 ASN B ND2 1 ATOM 10757 N N . ASN B 1 637 ? 3.597 -29.683 37.737 1.00 29.43 ? 657 ASN B N 1 ATOM 10758 C CA . ASN B 1 637 ? 3.091 -29.888 39.098 1.00 29.29 ? 657 ASN B CA 1 ATOM 10759 C C . ASN B 1 637 ? 4.082 -29.451 40.181 1.00 29.51 ? 657 ASN B C 1 ATOM 10760 O O . ASN B 1 637 ? 4.548 -30.252 40.982 1.00 29.27 ? 657 ASN B O 1 ATOM 10761 C CB . ASN B 1 637 ? 2.685 -31.350 39.293 1.00 29.26 ? 657 ASN B CB 1 ATOM 10762 C CG . ASN B 1 637 ? 1.837 -31.566 40.538 1.00 29.41 ? 657 ASN B CG 1 ATOM 10763 O OD1 . ASN B 1 637 ? 1.349 -30.613 41.155 1.00 30.14 ? 657 ASN B OD1 1 ATOM 10764 N ND2 . ASN B 1 637 ? 1.669 -32.826 40.921 1.00 28.92 ? 657 ASN B ND2 1 ATOM 10765 N N . GLU B 1 638 ? 4.380 -28.160 40.199 1.00 29.80 ? 658 GLU B N 1 ATOM 10766 C CA . GLU B 1 638 ? 5.433 -27.616 41.042 1.00 30.11 ? 658 GLU B CA 1 ATOM 10767 C C . GLU B 1 638 ? 5.003 -27.435 42.493 1.00 30.22 ? 658 GLU B C 1 ATOM 10768 O O . GLU B 1 638 ? 3.805 -27.379 42.808 1.00 29.96 ? 658 GLU B O 1 ATOM 10769 C CB . GLU B 1 638 ? 5.886 -26.265 40.501 1.00 30.41 ? 658 GLU B CB 1 ATOM 10770 C CG . GLU B 1 638 ? 6.407 -26.313 39.080 1.00 31.51 ? 658 GLU B CG 1 ATOM 10771 C CD . GLU B 1 638 ? 6.694 -24.935 38.533 1.00 33.41 ? 658 GLU B CD 1 ATOM 10772 O OE1 . GLU B 1 638 ? 5.743 -24.265 38.035 1.00 32.83 ? 658 GLU B OE1 1 ATOM 10773 O OE2 . GLU B 1 638 ? 7.885 -24.531 38.592 1.00 33.04 ? 658 GLU B OE2 1 ATOM 10774 N N . ASN B 1 639 ? 6.007 -27.343 43.362 1.00 29.97 ? 659 ASN B N 1 ATOM 10775 C CA . ASN B 1 639 ? 5.806 -27.050 44.773 1.00 29.84 ? 659 ASN B CA 1 ATOM 10776 C C . ASN B 1 639 ? 5.302 -25.622 44.950 1.00 29.71 ? 659 ASN B C 1 ATOM 10777 O O . ASN B 1 639 ? 5.873 -24.696 44.389 1.00 29.64 ? 659 ASN B O 1 ATOM 10778 C CB . ASN B 1 639 ? 7.125 -27.202 45.534 1.00 29.69 ? 659 ASN B CB 1 ATOM 10779 C CG . ASN B 1 639 ? 6.951 -27.061 47.025 1.00 28.87 ? 659 ASN B CG 1 ATOM 10780 O OD1 . ASN B 1 639 ? 7.143 -25.987 47.580 1.00 29.26 ? 659 ASN B OD1 1 ATOM 10781 N ND2 . ASN B 1 639 ? 6.568 -28.145 47.679 1.00 28.79 ? 659 ASN B ND2 1 ATOM 10782 N N . ILE B 1 640 ? 4.247 -25.452 45.738 1.00 30.10 ? 660 ILE B N 1 ATOM 10783 C CA . ILE B 1 640 ? 3.649 -24.131 45.972 1.00 30.44 ? 660 ILE B CA 1 ATOM 10784 C C . ILE B 1 640 ? 3.674 -23.755 47.458 1.00 31.12 ? 660 ILE B C 1 ATOM 10785 O O . ILE B 1 640 ? 2.899 -22.909 47.915 1.00 31.01 ? 660 ILE B O 1 ATOM 10786 C CB . ILE B 1 640 ? 2.191 -24.046 45.408 1.00 30.56 ? 660 ILE B CB 1 ATOM 10787 C CG1 . ILE B 1 640 ? 1.296 -25.147 45.986 1.00 30.35 ? 660 ILE B CG1 1 ATOM 10788 C CG2 . ILE B 1 640 ? 2.204 -24.128 43.882 1.00 29.46 ? 660 ILE B CG2 1 ATOM 10789 C CD1 . ILE B 1 640 ? -0.192 -24.938 45.705 1.00 30.39 ? 660 ILE B CD1 1 ATOM 10790 N N . GLU B 1 641 ? 4.580 -24.380 48.206 1.00 31.73 ? 661 GLU B N 1 ATOM 10791 C CA . GLU B 1 641 ? 4.803 -24.023 49.599 1.00 32.54 ? 661 GLU B CA 1 ATOM 10792 C C . GLU B 1 641 ? 5.790 -22.884 49.599 1.00 32.47 ? 661 GLU B C 1 ATOM 10793 O O . GLU B 1 641 ? 6.906 -23.040 49.113 1.00 33.61 ? 661 GLU B O 1 ATOM 10794 C CB . GLU B 1 641 ? 5.384 -25.199 50.380 1.00 32.88 ? 661 GLU B CB 1 ATOM 10795 C CG . GLU B 1 641 ? 4.578 -26.472 50.240 1.00 34.51 ? 661 GLU B CG 1 ATOM 10796 C CD . GLU B 1 641 ? 5.118 -27.597 51.089 1.00 36.80 ? 661 GLU B CD 1 ATOM 10797 O OE1 . GLU B 1 641 ? 4.414 -27.993 52.040 1.00 39.09 ? 661 GLU B OE1 1 ATOM 10798 O OE2 . GLU B 1 641 ? 6.236 -28.083 50.804 1.00 37.43 ? 661 GLU B OE2 1 ATOM 10799 N N . ASN B 1 642 ? 5.383 -21.736 50.114 1.00 32.17 ? 662 ASN B N 1 ATOM 10800 C CA . ASN B 1 642 ? 6.292 -20.616 50.248 1.00 32.11 ? 662 ASN B CA 1 ATOM 10801 C C . ASN B 1 642 ? 6.902 -20.211 48.900 1.00 31.48 ? 662 ASN B C 1 ATOM 10802 O O . ASN B 1 642 ? 8.122 -20.228 48.706 1.00 31.67 ? 662 ASN B O 1 ATOM 10803 C CB . ASN B 1 642 ? 7.378 -20.970 51.269 1.00 32.40 ? 662 ASN B CB 1 ATOM 10804 C CG . ASN B 1 642 ? 8.053 -19.757 51.834 1.00 34.03 ? 662 ASN B CG 1 ATOM 10805 O OD1 . ASN B 1 642 ? 7.397 -18.880 52.405 1.00 37.52 ? 662 ASN B OD1 1 ATOM 10806 N ND2 . ASN B 1 642 ? 9.378 -19.693 51.689 1.00 36.14 ? 662 ASN B ND2 1 ATOM 10807 N N . GLU B 1 643 ? 6.026 -19.862 47.965 1.00 30.45 ? 663 GLU B N 1 ATOM 10808 C CA . GLU B 1 643 ? 6.423 -19.425 46.633 1.00 29.83 ? 663 GLU B CA 1 ATOM 10809 C C . GLU B 1 643 ? 5.636 -18.198 46.243 1.00 28.81 ? 663 GLU B C 1 ATOM 10810 O O . GLU B 1 643 ? 4.697 -17.801 46.944 1.00 28.50 ? 663 GLU B O 1 ATOM 10811 C CB . GLU B 1 643 ? 6.156 -20.526 45.597 1.00 29.97 ? 663 GLU B CB 1 ATOM 10812 C CG . GLU B 1 643 ? 6.952 -21.808 45.788 1.00 31.43 ? 663 GLU B CG 1 ATOM 10813 C CD . GLU B 1 643 ? 8.463 -21.638 45.601 1.00 33.14 ? 663 GLU B CD 1 ATOM 10814 O OE1 . GLU B 1 643 ? 8.916 -20.557 45.168 1.00 33.27 ? 663 GLU B OE1 1 ATOM 10815 O OE2 . GLU B 1 643 ? 9.199 -22.607 45.888 1.00 35.61 ? 663 GLU B OE2 1 ATOM 10816 N N . ASP B 1 644 ? 6.021 -17.605 45.117 1.00 27.73 ? 664 ASP B N 1 ATOM 10817 C CA . ASP B 1 644 ? 5.223 -16.572 44.476 1.00 26.84 ? 664 ASP B CA 1 ATOM 10818 C C . ASP B 1 644 ? 4.079 -17.314 43.776 1.00 26.03 ? 664 ASP B C 1 ATOM 10819 O O . ASP B 1 644 ? 4.296 -18.004 42.782 1.00 26.08 ? 664 ASP B O 1 ATOM 10820 C CB . ASP B 1 644 ? 6.072 -15.746 43.490 1.00 26.88 ? 664 ASP B CB 1 ATOM 10821 C CG . ASP B 1 644 ? 5.320 -14.553 42.914 1.00 26.98 ? 664 ASP B CG 1 ATOM 10822 O OD1 . ASP B 1 644 ? 4.127 -14.392 43.226 1.00 26.99 ? 664 ASP B OD1 1 ATOM 10823 O OD2 . ASP B 1 644 ? 5.916 -13.765 42.145 1.00 27.87 ? 664 ASP B OD2 1 ATOM 10824 N N . LEU B 1 645 ? 2.873 -17.201 44.328 1.00 25.01 ? 665 LEU B N 1 ATOM 10825 C CA . LEU B 1 645 ? 1.712 -17.918 43.799 1.00 24.13 ? 665 LEU B CA 1 ATOM 10826 C C . LEU B 1 645 ? 0.867 -17.002 42.927 1.00 23.38 ? 665 LEU B C 1 ATOM 10827 O O . LEU B 1 645 ? 0.878 -15.784 43.097 1.00 23.21 ? 665 LEU B O 1 ATOM 10828 C CB . LEU B 1 645 ? 0.855 -18.470 44.942 1.00 24.21 ? 665 LEU B CB 1 ATOM 10829 C CG . LEU B 1 645 ? 1.581 -19.292 46.010 1.00 24.35 ? 665 LEU B CG 1 ATOM 10830 C CD1 . LEU B 1 645 ? 0.603 -19.806 47.054 1.00 23.63 ? 665 LEU B CD1 1 ATOM 10831 C CD2 . LEU B 1 645 ? 2.328 -20.449 45.364 1.00 24.20 ? 665 LEU B CD2 1 ATOM 10832 N N . VAL B 1 646 ? 0.147 -17.599 41.985 1.00 22.78 ? 666 VAL B N 1 ATOM 10833 C CA . VAL B 1 646 ? -0.812 -16.878 41.171 1.00 22.23 ? 666 VAL B CA 1 ATOM 10834 C C . VAL B 1 646 ? -2.123 -17.664 41.180 1.00 21.83 ? 666 VAL B C 1 ATOM 10835 O O . VAL B 1 646 ? -2.147 -18.833 40.786 1.00 21.79 ? 666 VAL B O 1 ATOM 10836 C CB . VAL B 1 646 ? -0.316 -16.708 39.716 1.00 22.17 ? 666 VAL B CB 1 ATOM 10837 C CG1 . VAL B 1 646 ? -1.388 -16.012 38.865 1.00 22.30 ? 666 VAL B CG1 1 ATOM 10838 C CG2 . VAL B 1 646 ? 1.012 -15.914 39.671 1.00 21.83 ? 666 VAL B CG2 1 ATOM 10839 N N . ALA B 1 647 ? -3.197 -17.035 41.652 1.00 21.36 ? 667 ALA B N 1 ATOM 10840 C CA . ALA B 1 647 ? -4.532 -17.631 41.562 1.00 21.03 ? 667 ALA B CA 1 ATOM 10841 C C . ALA B 1 647 ? -5.101 -17.270 40.208 1.00 20.69 ? 667 ALA B C 1 ATOM 10842 O O . ALA B 1 647 ? -4.955 -16.145 39.747 1.00 21.15 ? 667 ALA B O 1 ATOM 10843 C CB . ALA B 1 647 ? -5.452 -17.123 42.669 1.00 20.83 ? 667 ALA B CB 1 ATOM 10844 N N . TRP B 1 648 ? -5.740 -18.239 39.574 1.00 20.72 ? 668 TRP B N 1 ATOM 10845 C CA . TRP B 1 648 ? -6.424 -18.034 38.313 1.00 20.27 ? 668 TRP B CA 1 ATOM 10846 C C . TRP B 1 648 ? -7.889 -18.402 38.522 1.00 19.63 ? 668 TRP B C 1 ATOM 10847 O O . TRP B 1 648 ? -8.174 -19.513 38.947 1.00 19.94 ? 668 TRP B O 1 ATOM 10848 C CB . TRP B 1 648 ? -5.840 -18.967 37.262 1.00 20.40 ? 668 TRP B CB 1 ATOM 10849 C CG . TRP B 1 648 ? -4.399 -18.804 36.974 1.00 21.07 ? 668 TRP B CG 1 ATOM 10850 C CD1 . TRP B 1 648 ? -3.361 -19.421 37.613 1.00 22.18 ? 668 TRP B CD1 1 ATOM 10851 C CD2 . TRP B 1 648 ? -3.816 -18.022 35.923 1.00 22.14 ? 668 TRP B CD2 1 ATOM 10852 N NE1 . TRP B 1 648 ? -2.166 -19.054 37.033 1.00 22.45 ? 668 TRP B NE1 1 ATOM 10853 C CE2 . TRP B 1 648 ? -2.416 -18.204 35.992 1.00 22.07 ? 668 TRP B CE2 1 ATOM 10854 C CE3 . TRP B 1 648 ? -4.339 -17.193 34.925 1.00 22.68 ? 668 TRP B CE3 1 ATOM 10855 C CZ2 . TRP B 1 648 ? -1.532 -17.573 35.108 1.00 23.28 ? 668 TRP B CZ2 1 ATOM 10856 C CZ3 . TRP B 1 648 ? -3.457 -16.557 34.048 1.00 23.42 ? 668 TRP B CZ3 1 ATOM 10857 C CH2 . TRP B 1 648 ? -2.070 -16.755 34.144 1.00 22.87 ? 668 TRP B CH2 1 ATOM 10858 N N . VAL B 1 649 ? -8.804 -17.486 38.204 1.00 19.05 ? 669 VAL B N 1 ATOM 10859 C CA . VAL B 1 649 ? -10.226 -17.633 38.563 1.00 18.70 ? 669 VAL B CA 1 ATOM 10860 C C . VAL B 1 649 ? -11.145 -17.613 37.340 1.00 18.52 ? 669 VAL B C 1 ATOM 10861 O O . VAL B 1 649 ? -11.084 -16.686 36.536 1.00 18.33 ? 669 VAL B O 1 ATOM 10862 C CB . VAL B 1 649 ? -10.658 -16.514 39.547 1.00 18.75 ? 669 VAL B CB 1 ATOM 10863 C CG1 . VAL B 1 649 ? -12.137 -16.623 39.907 1.00 18.62 ? 669 VAL B CG1 1 ATOM 10864 C CG2 . VAL B 1 649 ? -9.816 -16.573 40.804 1.00 17.45 ? 669 VAL B CG2 1 ATOM 10865 N N . THR B 1 650 ? -11.966 -18.651 37.198 1.00 18.09 ? 670 THR B N 1 ATOM 10866 C CA . THR B 1 650 ? -13.016 -18.701 36.183 1.00 17.95 ? 670 THR B CA 1 ATOM 10867 C C . THR B 1 650 ? -14.377 -18.359 36.813 1.00 17.87 ? 670 THR B C 1 ATOM 10868 O O . THR B 1 650 ? -14.761 -18.942 37.831 1.00 18.09 ? 670 THR B O 1 ATOM 10869 C CB . THR B 1 650 ? -13.121 -20.102 35.534 1.00 18.00 ? 670 THR B CB 1 ATOM 10870 O OG1 . THR B 1 650 ? -11.873 -20.460 34.920 1.00 17.86 ? 670 THR B OG1 1 ATOM 10871 C CG2 . THR B 1 650 ? -14.210 -20.129 34.479 1.00 17.91 ? 670 THR B CG2 1 ATOM 10872 N N . VAL B 1 651 ? -15.074 -17.393 36.227 1.00 17.42 ? 671 VAL B N 1 ATOM 10873 C CA . VAL B 1 651 ? -16.440 -17.065 36.626 1.00 17.41 ? 671 VAL B CA 1 ATOM 10874 C C . VAL B 1 651 ? -17.298 -16.987 35.378 1.00 17.74 ? 671 VAL B C 1 ATOM 10875 O O . VAL B 1 651 ? -16.794 -16.731 34.274 1.00 16.77 ? 671 VAL B O 1 ATOM 10876 C CB . VAL B 1 651 ? -16.531 -15.736 37.426 1.00 17.43 ? 671 VAL B CB 1 ATOM 10877 C CG1 . VAL B 1 651 ? -15.699 -15.822 38.682 1.00 17.23 ? 671 VAL B CG1 1 ATOM 10878 C CG2 . VAL B 1 651 ? -16.100 -14.526 36.588 1.00 16.93 ? 671 VAL B CG2 1 ATOM 10879 N N . GLY B 1 652 ? -18.596 -17.225 35.539 1.00 18.08 ? 672 GLY B N 1 ATOM 10880 C CA . GLY B 1 652 ? -19.489 -17.237 34.392 1.00 18.02 ? 672 GLY B CA 1 ATOM 10881 C C . GLY B 1 652 ? -20.908 -17.650 34.719 1.00 18.53 ? 672 GLY B C 1 ATOM 10882 O O . GLY B 1 652 ? -21.251 -17.868 35.873 1.00 18.78 ? 672 GLY B O 1 ATOM 10883 N N . PHE B 1 653 ? -21.731 -17.757 33.684 1.00 18.51 ? 673 PHE B N 1 ATOM 10884 C CA . PHE B 1 653 ? -23.108 -18.171 33.857 1.00 18.69 ? 673 PHE B CA 1 ATOM 10885 C C . PHE B 1 653 ? -23.716 -18.634 32.552 1.00 18.69 ? 673 PHE B C 1 ATOM 10886 O O . PHE B 1 653 ? -23.411 -18.113 31.462 1.00 18.69 ? 673 PHE B O 1 ATOM 10887 C CB . PHE B 1 653 ? -23.952 -17.037 34.464 1.00 18.68 ? 673 PHE B CB 1 ATOM 10888 C CG . PHE B 1 653 ? -23.983 -15.783 33.641 1.00 18.15 ? 673 PHE B CG 1 ATOM 10889 C CD1 . PHE B 1 653 ? -25.023 -15.548 32.747 1.00 17.83 ? 673 PHE B CD1 1 ATOM 10890 C CD2 . PHE B 1 653 ? -22.990 -14.817 33.781 1.00 18.73 ? 673 PHE B CD2 1 ATOM 10891 C CE1 . PHE B 1 653 ? -25.061 -14.391 31.987 1.00 18.00 ? 673 PHE B CE1 1 ATOM 10892 C CE2 . PHE B 1 653 ? -23.020 -13.651 33.031 1.00 17.67 ? 673 PHE B CE2 1 ATOM 10893 C CZ . PHE B 1 653 ? -24.053 -13.435 32.129 1.00 19.39 ? 673 PHE B CZ 1 ATOM 10894 N N . LEU B 1 654 ? -24.581 -19.629 32.672 1.00 18.75 ? 674 LEU B N 1 ATOM 10895 C CA . LEU B 1 654 ? -25.415 -20.058 31.565 1.00 18.89 ? 674 LEU B CA 1 ATOM 10896 C C . LEU B 1 654 ? -26.418 -18.956 31.284 1.00 18.44 ? 674 LEU B C 1 ATOM 10897 O O . LEU B 1 654 ? -26.992 -18.401 32.196 1.00 19.04 ? 674 LEU B O 1 ATOM 10898 C CB . LEU B 1 654 ? -26.128 -21.360 31.917 1.00 18.77 ? 674 LEU B CB 1 ATOM 10899 C CG . LEU B 1 654 ? -27.074 -21.914 30.853 1.00 19.29 ? 674 LEU B CG 1 ATOM 10900 C CD1 . LEU B 1 654 ? -26.330 -22.189 29.540 1.00 18.47 ? 674 LEU B CD1 1 ATOM 10901 C CD2 . LEU B 1 654 ? -27.734 -23.161 31.383 1.00 17.78 ? 674 LEU B CD2 1 ATOM 10902 N N . HIS B 1 655 ? -26.611 -18.622 30.018 1.00 18.03 ? 675 HIS B N 1 ATOM 10903 C CA . HIS B 1 655 ? -27.635 -17.663 29.640 1.00 17.64 ? 675 HIS B CA 1 ATOM 10904 C C . HIS B 1 655 ? -28.534 -18.351 28.624 1.00 17.72 ? 675 HIS B C 1 ATOM 10905 O O . HIS B 1 655 ? -28.128 -18.605 27.499 1.00 17.11 ? 675 HIS B O 1 ATOM 10906 C CB . HIS B 1 655 ? -26.975 -16.401 29.082 1.00 17.91 ? 675 HIS B CB 1 ATOM 10907 C CG . HIS B 1 655 ? -27.929 -15.328 28.651 1.00 16.79 ? 675 HIS B CG 1 ATOM 10908 N ND1 . HIS B 1 655 ? -27.516 -14.229 27.930 1.00 16.01 ? 675 HIS B ND1 1 ATOM 10909 C CD2 . HIS B 1 655 ? -29.265 -15.186 28.820 1.00 16.20 ? 675 HIS B CD2 1 ATOM 10910 C CE1 . HIS B 1 655 ? -28.555 -13.452 27.680 1.00 16.91 ? 675 HIS B CE1 1 ATOM 10911 N NE2 . HIS B 1 655 ? -29.628 -14.008 28.216 1.00 16.72 ? 675 HIS B NE2 1 ATOM 10912 N N . ILE B 1 656 ? -29.730 -18.729 29.064 1.00 17.77 ? 676 ILE B N 1 ATOM 10913 C CA . ILE B 1 656 ? -30.763 -19.187 28.152 1.00 17.73 ? 676 ILE B CA 1 ATOM 10914 C C . ILE B 1 656 ? -31.593 -17.943 27.878 1.00 17.63 ? 676 ILE B C 1 ATOM 10915 O O . ILE B 1 656 ? -32.241 -17.436 28.784 1.00 17.58 ? 676 ILE B O 1 ATOM 10916 C CB . ILE B 1 656 ? -31.628 -20.297 28.765 1.00 18.12 ? 676 ILE B CB 1 ATOM 10917 C CG1 . ILE B 1 656 ? -30.775 -21.542 29.068 1.00 17.79 ? 676 ILE B CG1 1 ATOM 10918 C CG2 . ILE B 1 656 ? -32.774 -20.679 27.811 1.00 17.87 ? 676 ILE B CG2 1 ATOM 10919 C CD1 . ILE B 1 656 ? -31.507 -22.635 29.839 1.00 16.14 ? 676 ILE B CD1 1 ATOM 10920 N N . PRO B 1 657 ? -31.544 -17.412 26.641 1.00 17.43 ? 677 PRO B N 1 ATOM 10921 C CA . PRO B 1 657 ? -32.260 -16.159 26.453 1.00 17.28 ? 677 PRO B CA 1 ATOM 10922 C C . PRO B 1 657 ? -33.759 -16.260 26.659 1.00 17.23 ? 677 PRO B C 1 ATOM 10923 O O . PRO B 1 657 ? -34.341 -17.341 26.515 1.00 17.33 ? 677 PRO B O 1 ATOM 10924 C CB . PRO B 1 657 ? -31.911 -15.775 25.017 1.00 17.44 ? 677 PRO B CB 1 ATOM 10925 C CG . PRO B 1 657 ? -30.534 -16.362 24.839 1.00 16.89 ? 677 PRO B CG 1 ATOM 10926 C CD . PRO B 1 657 ? -30.654 -17.692 25.500 1.00 17.28 ? 677 PRO B CD 1 ATOM 10927 N N . HIS B 1 658 ? -34.357 -15.128 27.036 1.00 16.90 ? 678 HIS B N 1 ATOM 10928 C CA . HIS B 1 658 ? -35.787 -15.031 27.292 1.00 16.79 ? 678 HIS B CA 1 ATOM 10929 C C . HIS B 1 658 ? -36.278 -13.699 26.724 1.00 16.42 ? 678 HIS B C 1 ATOM 10930 O O . HIS B 1 658 ? -35.474 -12.848 26.371 1.00 16.35 ? 678 HIS B O 1 ATOM 10931 C CB . HIS B 1 658 ? -36.113 -15.191 28.796 1.00 16.64 ? 678 HIS B CB 1 ATOM 10932 C CG . HIS B 1 658 ? -35.201 -14.436 29.712 1.00 17.04 ? 678 HIS B CG 1 ATOM 10933 N ND1 . HIS B 1 658 ? -35.628 -13.376 30.482 1.00 18.07 ? 678 HIS B ND1 1 ATOM 10934 C CD2 . HIS B 1 658 ? -33.884 -14.601 30.000 1.00 19.31 ? 678 HIS B CD2 1 ATOM 10935 C CE1 . HIS B 1 658 ? -34.613 -12.910 31.192 1.00 19.22 ? 678 HIS B CE1 1 ATOM 10936 N NE2 . HIS B 1 658 ? -33.545 -13.641 30.926 1.00 18.72 ? 678 HIS B NE2 1 ATOM 10937 N N . SER B 1 659 ? -37.592 -13.542 26.601 1.00 16.16 ? 679 SER B N 1 ATOM 10938 C CA . SER B 1 659 ? -38.161 -12.397 25.892 1.00 16.38 ? 679 SER B CA 1 ATOM 10939 C C . SER B 1 659 ? -37.792 -11.061 26.528 1.00 16.36 ? 679 SER B C 1 ATOM 10940 O O . SER B 1 659 ? -37.678 -10.052 25.833 1.00 15.93 ? 679 SER B O 1 ATOM 10941 C CB . SER B 1 659 ? -39.681 -12.526 25.748 1.00 16.17 ? 679 SER B CB 1 ATOM 10942 O OG . SER B 1 659 ? -40.286 -12.886 26.968 1.00 15.52 ? 679 SER B OG 1 ATOM 10943 N N . GLU B 1 660 ? -37.558 -11.051 27.831 1.00 16.68 ? 680 GLU B N 1 ATOM 10944 C CA . GLU B 1 660 ? -37.144 -9.807 28.485 1.00 17.16 ? 680 GLU B CA 1 ATOM 10945 C C . GLU B 1 660 ? -35.741 -9.333 28.044 1.00 17.63 ? 680 GLU B C 1 ATOM 10946 O O . GLU B 1 660 ? -35.371 -8.183 28.340 1.00 17.98 ? 680 GLU B O 1 ATOM 10947 C CB . GLU B 1 660 ? -37.213 -9.928 30.009 1.00 17.04 ? 680 GLU B CB 1 ATOM 10948 C CG . GLU B 1 660 ? -38.635 -10.177 30.562 1.00 16.62 ? 680 GLU B CG 1 ATOM 10949 C CD . GLU B 1 660 ? -39.069 -11.646 30.569 1.00 15.57 ? 680 GLU B CD 1 ATOM 10950 O OE1 . GLU B 1 660 ? -38.290 -12.526 30.129 1.00 14.58 ? 680 GLU B OE1 1 ATOM 10951 O OE2 . GLU B 1 660 ? -40.201 -11.918 31.031 1.00 13.24 ? 680 GLU B OE2 1 ATOM 10952 N N . ASP B 1 661 ? -34.976 -10.188 27.349 1.00 17.71 ? 681 ASP B N 1 ATOM 10953 C CA . ASP B 1 661 ? -33.672 -9.787 26.753 1.00 18.14 ? 681 ASP B CA 1 ATOM 10954 C C . ASP B 1 661 ? -33.827 -8.871 25.529 1.00 18.02 ? 681 ASP B C 1 ATOM 10955 O O . ASP B 1 661 ? -32.829 -8.425 24.964 1.00 17.81 ? 681 ASP B O 1 ATOM 10956 C CB . ASP B 1 661 ? -32.841 -11.020 26.322 1.00 18.48 ? 681 ASP B CB 1 ATOM 10957 C CG . ASP B 1 661 ? -32.203 -11.758 27.491 1.00 19.58 ? 681 ASP B CG 1 ATOM 10958 O OD1 . ASP B 1 661 ? -31.770 -11.101 28.467 1.00 19.84 ? 681 ASP B OD1 1 ATOM 10959 O OD2 . ASP B 1 661 ? -32.123 -13.005 27.423 1.00 20.73 ? 681 ASP B OD2 1 ATOM 10960 N N . ILE B 1 662 ? -35.069 -8.607 25.116 1.00 17.71 ? 682 ILE B N 1 ATOM 10961 C CA . ILE B 1 662 ? -35.354 -7.755 23.969 1.00 17.85 ? 682 ILE B CA 1 ATOM 10962 C C . ILE B 1 662 ? -35.694 -6.332 24.421 1.00 17.95 ? 682 ILE B C 1 ATOM 10963 O O . ILE B 1 662 ? -36.590 -6.156 25.260 1.00 18.11 ? 682 ILE B O 1 ATOM 10964 C CB . ILE B 1 662 ? -36.542 -8.316 23.159 1.00 17.53 ? 682 ILE B CB 1 ATOM 10965 C CG1 . ILE B 1 662 ? -36.236 -9.730 22.650 1.00 18.28 ? 682 ILE B CG1 1 ATOM 10966 C CG2 . ILE B 1 662 ? -36.880 -7.397 21.988 1.00 18.27 ? 682 ILE B CG2 1 ATOM 10967 C CD1 . ILE B 1 662 ? -35.039 -9.817 21.713 1.00 19.14 ? 682 ILE B CD1 1 ATOM 10968 N N . PRO B 1 663 ? -35.003 -5.301 23.870 1.00 17.92 ? 683 PRO B N 1 ATOM 10969 C CA . PRO B 1 663 ? -33.942 -5.283 22.858 1.00 17.82 ? 683 PRO B CA 1 ATOM 10970 C C . PRO B 1 663 ? -32.580 -5.667 23.382 1.00 17.98 ? 683 PRO B C 1 ATOM 10971 O O . PRO B 1 663 ? -31.727 -6.099 22.595 1.00 18.15 ? 683 PRO B O 1 ATOM 10972 C CB . PRO B 1 663 ? -33.896 -3.818 22.424 1.00 18.25 ? 683 PRO B CB 1 ATOM 10973 C CG . PRO B 1 663 ? -34.313 -3.057 23.663 1.00 17.85 ? 683 PRO B CG 1 ATOM 10974 C CD . PRO B 1 663 ? -35.377 -3.932 24.280 1.00 17.93 ? 683 PRO B CD 1 ATOM 10975 N N . ASN B 1 664 ? -32.369 -5.504 24.687 1.00 17.74 ? 684 ASN B N 1 ATOM 10976 C CA . ASN B 1 664 ? -31.083 -5.807 25.311 1.00 17.91 ? 684 ASN B CA 1 ATOM 10977 C C . ASN B 1 664 ? -31.204 -6.652 26.580 1.00 18.05 ? 684 ASN B C 1 ATOM 10978 O O . ASN B 1 664 ? -32.183 -6.525 27.330 1.00 18.12 ? 684 ASN B O 1 ATOM 10979 C CB . ASN B 1 664 ? -30.401 -4.506 25.735 1.00 18.08 ? 684 ASN B CB 1 ATOM 10980 C CG . ASN B 1 664 ? -29.642 -3.812 24.609 1.00 18.50 ? 684 ASN B CG 1 ATOM 10981 O OD1 . ASN B 1 664 ? -28.819 -2.946 24.894 1.00 21.14 ? 684 ASN B OD1 1 ATOM 10982 N ND2 . ASN B 1 664 ? -29.900 -4.178 23.348 1.00 17.27 ? 684 ASN B ND2 1 ATOM 10983 N N A THR B 1 665 ? -30.205 -7.506 26.810 0.50 17.85 ? 685 THR B N 1 ATOM 10984 N N B THR B 1 665 ? -30.213 -7.505 26.820 0.50 18.18 ? 685 THR B N 1 ATOM 10985 C CA A THR B 1 665 ? -29.972 -8.114 28.117 0.50 17.80 ? 685 THR B CA 1 ATOM 10986 C CA B THR B 1 665 ? -30.047 -8.130 28.120 0.50 18.46 ? 685 THR B CA 1 ATOM 10987 C C A THR B 1 665 ? -29.751 -6.989 29.133 0.50 17.93 ? 685 THR B C 1 ATOM 10988 C C B THR B 1 665 ? -29.744 -7.021 29.134 0.50 18.26 ? 685 THR B C 1 ATOM 10989 O O A THR B 1 665 ? -29.069 -6.010 28.830 0.50 17.80 ? 685 THR B O 1 ATOM 10990 O O B THR B 1 665 ? -29.002 -6.089 28.831 0.50 18.12 ? 685 THR B O 1 ATOM 10991 C CB A THR B 1 665 ? -28.698 -9.002 28.106 0.50 18.09 ? 685 THR B CB 1 ATOM 10992 C CB B THR B 1 665 ? -28.877 -9.129 28.111 0.50 18.86 ? 685 THR B CB 1 ATOM 10993 O OG1 A THR B 1 665 ? -28.872 -10.107 27.210 0.50 17.10 ? 685 THR B OG1 1 ATOM 10994 O OG1 B THR B 1 665 ? -27.641 -8.414 28.010 0.50 19.91 ? 685 THR B OG1 1 ATOM 10995 C CG2 A THR B 1 665 ? -28.375 -9.520 29.516 0.50 16.96 ? 685 THR B CG2 1 ATOM 10996 C CG2 B THR B 1 665 ? -28.993 -10.075 26.941 0.50 18.46 ? 685 THR B CG2 1 ATOM 10997 N N . ALA B 1 666 ? -30.336 -7.124 30.321 1.00 18.00 ? 686 ALA B N 1 ATOM 10998 C CA . ALA B 1 666 ? -30.183 -6.123 31.383 1.00 17.92 ? 686 ALA B CA 1 ATOM 10999 C C . ALA B 1 666 ? -29.178 -6.623 32.437 1.00 18.40 ? 686 ALA B C 1 ATOM 11000 O O . ALA B 1 666 ? -28.919 -7.828 32.536 1.00 17.58 ? 686 ALA B O 1 ATOM 11001 C CB . ALA B 1 666 ? -31.540 -5.822 32.025 1.00 17.58 ? 686 ALA B CB 1 ATOM 11002 N N . THR B 1 667 ? -28.620 -5.692 33.219 1.00 19.14 ? 687 THR B N 1 ATOM 11003 C CA . THR B 1 667 ? -27.589 -6.030 34.210 1.00 19.40 ? 687 THR B CA 1 ATOM 11004 C C . THR B 1 667 ? -28.071 -6.655 35.527 1.00 20.04 ? 687 THR B C 1 ATOM 11005 O O . THR B 1 667 ? -27.285 -7.352 36.169 1.00 19.41 ? 687 THR B O 1 ATOM 11006 C CB . THR B 1 667 ? -26.738 -4.819 34.591 1.00 19.45 ? 687 THR B CB 1 ATOM 11007 O OG1 . THR B 1 667 ? -27.583 -3.785 35.104 1.00 18.58 ? 687 THR B OG1 1 ATOM 11008 C CG2 . THR B 1 667 ? -25.929 -4.310 33.370 1.00 19.69 ? 687 THR B CG2 1 ATOM 11009 N N . PRO B 1 668 ? -29.330 -6.391 35.953 1.00 20.77 ? 688 PRO B N 1 ATOM 11010 C CA . PRO B 1 668 ? -29.710 -6.965 37.247 1.00 21.42 ? 688 PRO B CA 1 ATOM 11011 C C . PRO B 1 668 ? -29.618 -8.482 37.237 1.00 21.82 ? 688 PRO B C 1 ATOM 11012 O O . PRO B 1 668 ? -30.174 -9.128 36.353 1.00 22.18 ? 688 PRO B O 1 ATOM 11013 C CB . PRO B 1 668 ? -31.157 -6.485 37.449 1.00 21.42 ? 688 PRO B CB 1 ATOM 11014 C CG . PRO B 1 668 ? -31.240 -5.229 36.670 1.00 21.34 ? 688 PRO B CG 1 ATOM 11015 C CD . PRO B 1 668 ? -30.356 -5.456 35.456 1.00 20.87 ? 688 PRO B CD 1 ATOM 11016 N N . GLY B 1 669 ? -28.865 -9.020 38.194 1.00 22.58 ? 689 GLY B N 1 ATOM 11017 C CA . GLY B 1 669 ? -28.584 -10.447 38.285 1.00 22.94 ? 689 GLY B CA 1 ATOM 11018 C C . GLY B 1 669 ? -27.693 -11.029 37.198 1.00 23.46 ? 689 GLY B C 1 ATOM 11019 O O . GLY B 1 669 ? -27.493 -12.240 37.162 1.00 23.90 ? 689 GLY B O 1 ATOM 11020 N N . ASN B 1 670 ? -27.167 -10.203 36.299 1.00 23.32 ? 690 ASN B N 1 ATOM 11021 C CA . ASN B 1 670 ? -26.332 -10.711 35.215 1.00 23.48 ? 690 ASN B CA 1 ATOM 11022 C C . ASN B 1 670 ? -24.895 -10.274 35.426 1.00 22.95 ? 690 ASN B C 1 ATOM 11023 O O . ASN B 1 670 ? -24.294 -9.666 34.556 1.00 22.72 ? 690 ASN B O 1 ATOM 11024 C CB . ASN B 1 670 ? -26.848 -10.237 33.846 1.00 24.00 ? 690 ASN B CB 1 ATOM 11025 C CG . ASN B 1 670 ? -27.957 -11.111 33.311 1.00 25.17 ? 690 ASN B CG 1 ATOM 11026 O OD1 . ASN B 1 670 ? -27.944 -12.318 33.514 1.00 27.02 ? 690 ASN B OD1 1 ATOM 11027 N ND2 . ASN B 1 670 ? -28.936 -10.506 32.625 1.00 26.58 ? 690 ASN B ND2 1 ATOM 11028 N N . SER B 1 671 ? -24.360 -10.582 36.602 1.00 22.57 ? 691 SER B N 1 ATOM 11029 C CA . SER B 1 671 ? -22.985 -10.259 36.913 1.00 22.34 ? 691 SER B CA 1 ATOM 11030 C C . SER B 1 671 ? -22.314 -11.367 37.701 1.00 21.59 ? 691 SER B C 1 ATOM 11031 O O . SER B 1 671 ? -22.954 -12.096 38.455 1.00 21.01 ? 691 SER B O 1 ATOM 11032 C CB . SER B 1 671 ? -22.879 -8.927 37.662 1.00 22.41 ? 691 SER B CB 1 ATOM 11033 O OG . SER B 1 671 ? -23.272 -9.049 39.011 1.00 24.88 ? 691 SER B OG 1 ATOM 11034 N N . VAL B 1 672 ? -21.009 -11.477 37.493 1.00 21.03 ? 692 VAL B N 1 ATOM 11035 C CA . VAL B 1 672 ? -20.169 -12.427 38.196 1.00 20.72 ? 692 VAL B CA 1 ATOM 11036 C C . VAL B 1 672 ? -18.873 -11.747 38.600 1.00 20.70 ? 692 VAL B C 1 ATOM 11037 O O . VAL B 1 672 ? -18.551 -10.640 38.126 1.00 20.49 ? 692 VAL B O 1 ATOM 11038 C CB . VAL B 1 672 ? -19.838 -13.634 37.307 1.00 20.98 ? 692 VAL B CB 1 ATOM 11039 C CG1 . VAL B 1 672 ? -21.054 -14.576 37.226 1.00 21.42 ? 692 VAL B CG1 1 ATOM 11040 C CG2 . VAL B 1 672 ? -19.378 -13.173 35.915 1.00 19.93 ? 692 VAL B CG2 1 ATOM 11041 N N . GLY B 1 673 ? -18.126 -12.411 39.468 1.00 20.11 ? 693 GLY B N 1 ATOM 11042 C CA . GLY B 1 673 ? -16.846 -11.889 39.894 1.00 20.04 ? 693 GLY B CA 1 ATOM 11043 C C . GLY B 1 673 ? -16.330 -12.616 41.099 1.00 19.97 ? 693 GLY B C 1 ATOM 11044 O O . GLY B 1 673 ? -16.643 -13.789 41.320 1.00 19.99 ? 693 GLY B O 1 ATOM 11045 N N . PHE B 1 674 ? -15.525 -11.911 41.878 1.00 20.44 ? 694 PHE B N 1 ATOM 11046 C CA . PHE B 1 674 ? -14.979 -12.455 43.114 1.00 20.60 ? 694 PHE B CA 1 ATOM 11047 C C . PHE B 1 674 ? -14.610 -11.326 44.058 1.00 20.99 ? 694 PHE B C 1 ATOM 11048 O O . PHE B 1 674 ? -14.482 -10.173 43.640 1.00 20.56 ? 694 PHE B O 1 ATOM 11049 C CB . PHE B 1 674 ? -13.765 -13.352 42.824 1.00 20.83 ? 694 PHE B CB 1 ATOM 11050 C CG . PHE B 1 674 ? -12.638 -12.650 42.101 1.00 21.24 ? 694 PHE B CG 1 ATOM 11051 C CD1 . PHE B 1 674 ? -11.575 -12.104 42.806 1.00 21.83 ? 694 PHE B CD1 1 ATOM 11052 C CD2 . PHE B 1 674 ? -12.641 -12.537 40.726 1.00 22.06 ? 694 PHE B CD2 1 ATOM 11053 C CE1 . PHE B 1 674 ? -10.528 -11.445 42.149 1.00 21.48 ? 694 PHE B CE1 1 ATOM 11054 C CE2 . PHE B 1 674 ? -11.591 -11.876 40.058 1.00 23.00 ? 694 PHE B CE2 1 ATOM 11055 C CZ . PHE B 1 674 ? -10.537 -11.336 40.778 1.00 22.04 ? 694 PHE B CZ 1 ATOM 11056 N N . LEU B 1 675 ? -14.481 -11.666 45.337 1.00 21.92 ? 695 LEU B N 1 ATOM 11057 C CA . LEU B 1 675 ? -13.997 -10.741 46.349 1.00 22.76 ? 695 LEU B CA 1 ATOM 11058 C C . LEU B 1 675 ? -12.662 -11.225 46.880 1.00 22.88 ? 695 LEU B C 1 ATOM 11059 O O . LEU B 1 675 ? -12.379 -12.414 46.875 1.00 23.21 ? 695 LEU B O 1 ATOM 11060 C CB . LEU B 1 675 ? -14.983 -10.627 47.518 1.00 23.39 ? 695 LEU B CB 1 ATOM 11061 C CG . LEU B 1 675 ? -16.182 -9.705 47.323 1.00 24.24 ? 695 LEU B CG 1 ATOM 11062 C CD1 . LEU B 1 675 ? -17.040 -10.256 46.224 1.00 27.06 ? 695 LEU B CD1 1 ATOM 11063 C CD2 . LEU B 1 675 ? -16.969 -9.592 48.606 1.00 26.04 ? 695 LEU B CD2 1 ATOM 11064 N N . LEU B 1 676 ? -11.848 -10.274 47.322 1.00 23.07 ? 696 LEU B N 1 ATOM 11065 C CA . LEU B 1 676 ? -10.633 -10.554 48.059 1.00 23.09 ? 696 LEU B CA 1 ATOM 11066 C C . LEU B 1 676 ? -10.778 -9.865 49.418 1.00 23.25 ? 696 LEU B C 1 ATOM 11067 O O . LEU B 1 676 ? -10.886 -8.644 49.487 1.00 23.91 ? 696 LEU B O 1 ATOM 11068 C CB . LEU B 1 676 ? -9.416 -10.024 47.315 1.00 22.70 ? 696 LEU B CB 1 ATOM 11069 C CG . LEU B 1 676 ? -9.168 -10.565 45.908 1.00 22.09 ? 696 LEU B CG 1 ATOM 11070 C CD1 . LEU B 1 676 ? -8.065 -9.750 45.227 1.00 21.97 ? 696 LEU B CD1 1 ATOM 11071 C CD2 . LEU B 1 676 ? -8.824 -12.044 45.921 1.00 21.43 ? 696 LEU B CD2 1 ATOM 11072 N N . ARG B 1 677 ? -10.801 -10.653 50.481 1.00 23.12 ? 697 ARG B N 1 ATOM 11073 C CA . ARG B 1 677 ? -11.115 -10.164 51.814 1.00 23.74 ? 697 ARG B CA 1 ATOM 11074 C C . ARG B 1 677 ? -9.934 -10.391 52.740 1.00 23.73 ? 697 ARG B C 1 ATOM 11075 O O . ARG B 1 677 ? -9.364 -11.486 52.739 1.00 23.74 ? 697 ARG B O 1 ATOM 11076 C CB . ARG B 1 677 ? -12.312 -10.930 52.390 1.00 23.81 ? 697 ARG B CB 1 ATOM 11077 C CG . ARG B 1 677 ? -13.546 -10.906 51.482 1.00 25.05 ? 697 ARG B CG 1 ATOM 11078 C CD . ARG B 1 677 ? -14.673 -11.799 51.995 1.00 25.27 ? 697 ARG B CD 1 ATOM 11079 N NE . ARG B 1 677 ? -15.063 -11.455 53.354 1.00 25.86 ? 697 ARG B NE 1 ATOM 11080 C CZ . ARG B 1 677 ? -16.204 -11.823 53.929 1.00 27.73 ? 697 ARG B CZ 1 ATOM 11081 N NH1 . ARG B 1 677 ? -17.115 -12.535 53.267 1.00 28.50 ? 697 ARG B NH1 1 ATOM 11082 N NH2 . ARG B 1 677 ? -16.440 -11.459 55.178 1.00 28.09 ? 697 ARG B NH2 1 ATOM 11083 N N . PRO B 1 678 ? -9.584 -9.377 53.551 1.00 23.72 ? 698 PRO B N 1 ATOM 11084 C CA . PRO B 1 678 ? -8.582 -9.575 54.598 1.00 23.72 ? 698 PRO B CA 1 ATOM 11085 C C . PRO B 1 678 ? -9.022 -10.660 55.583 1.00 23.29 ? 698 PRO B C 1 ATOM 11086 O O . PRO B 1 678 ? -10.158 -10.618 56.071 1.00 22.97 ? 698 PRO B O 1 ATOM 11087 C CB . PRO B 1 678 ? -8.528 -8.221 55.317 1.00 23.56 ? 698 PRO B CB 1 ATOM 11088 C CG . PRO B 1 678 ? -9.240 -7.281 54.501 1.00 24.22 ? 698 PRO B CG 1 ATOM 11089 C CD . PRO B 1 678 ? -10.136 -8.013 53.563 1.00 23.77 ? 698 PRO B CD 1 ATOM 11090 N N . PHE B 1 679 ? -8.142 -11.625 55.845 1.00 22.71 ? 699 PHE B N 1 ATOM 11091 C CA . PHE B 1 679 ? -8.424 -12.681 56.814 1.00 22.82 ? 699 PHE B CA 1 ATOM 11092 C C . PHE B 1 679 ? -7.239 -12.843 57.779 1.00 23.19 ? 699 PHE B C 1 ATOM 11093 O O . PHE B 1 679 ? -6.253 -13.512 57.462 1.00 22.96 ? 699 PHE B O 1 ATOM 11094 C CB . PHE B 1 679 ? -8.725 -13.990 56.101 1.00 22.41 ? 699 PHE B CB 1 ATOM 11095 C CG . PHE B 1 679 ? -9.179 -15.091 57.018 1.00 21.95 ? 699 PHE B CG 1 ATOM 11096 C CD1 . PHE B 1 679 ? -10.518 -15.215 57.361 1.00 21.72 ? 699 PHE B CD1 1 ATOM 11097 C CD2 . PHE B 1 679 ? -8.274 -16.007 57.523 1.00 21.01 ? 699 PHE B CD2 1 ATOM 11098 C CE1 . PHE B 1 679 ? -10.947 -16.225 58.198 1.00 21.10 ? 699 PHE B CE1 1 ATOM 11099 C CE2 . PHE B 1 679 ? -8.688 -17.017 58.368 1.00 21.44 ? 699 PHE B CE2 1 ATOM 11100 C CZ . PHE B 1 679 ? -10.040 -17.130 58.703 1.00 20.97 ? 699 PHE B CZ 1 ATOM 11101 N N . ASN B 1 680 ? -7.365 -12.212 58.947 1.00 23.47 ? 700 ASN B N 1 ATOM 11102 C CA . ASN B 1 680 ? -6.310 -12.143 59.978 1.00 23.42 ? 700 ASN B CA 1 ATOM 11103 C C . ASN B 1 680 ? -5.083 -11.374 59.501 1.00 23.87 ? 700 ASN B C 1 ATOM 11104 O O . ASN B 1 680 ? -3.984 -11.553 60.032 1.00 23.63 ? 700 ASN B O 1 ATOM 11105 C CB . ASN B 1 680 ? -5.918 -13.531 60.487 1.00 23.30 ? 700 ASN B CB 1 ATOM 11106 C CG . ASN B 1 680 ? -7.050 -14.228 61.203 1.00 22.98 ? 700 ASN B CG 1 ATOM 11107 O OD1 . ASN B 1 680 ? -7.785 -13.615 61.994 1.00 22.31 ? 700 ASN B OD1 1 ATOM 11108 N ND2 . ASN B 1 680 ? -7.206 -15.517 60.929 1.00 21.11 ? 700 ASN B ND2 1 ATOM 11109 N N . PHE B 1 681 ? -5.297 -10.505 58.514 1.00 24.12 ? 701 PHE B N 1 ATOM 11110 C CA . PHE B 1 681 ? -4.235 -9.718 57.917 1.00 24.71 ? 701 PHE B CA 1 ATOM 11111 C C . PHE B 1 681 ? -3.962 -8.486 58.770 1.00 24.87 ? 701 PHE B C 1 ATOM 11112 O O . PHE B 1 681 ? -2.808 -8.123 58.988 1.00 24.49 ? 701 PHE B O 1 ATOM 11113 C CB . PHE B 1 681 ? -4.625 -9.299 56.504 1.00 24.72 ? 701 PHE B CB 1 ATOM 11114 C CG . PHE B 1 681 ? -3.502 -8.696 55.717 1.00 25.37 ? 701 PHE B CG 1 ATOM 11115 C CD1 . PHE B 1 681 ? -3.281 -7.334 55.737 1.00 25.65 ? 701 PHE B CD1 1 ATOM 11116 C CD2 . PHE B 1 681 ? -2.679 -9.494 54.939 1.00 26.66 ? 701 PHE B CD2 1 ATOM 11117 C CE1 . PHE B 1 681 ? -2.252 -6.772 55.011 1.00 27.09 ? 701 PHE B CE1 1 ATOM 11118 C CE2 . PHE B 1 681 ? -1.642 -8.937 54.205 1.00 27.67 ? 701 PHE B CE2 1 ATOM 11119 C CZ . PHE B 1 681 ? -1.429 -7.577 54.239 1.00 27.24 ? 701 PHE B CZ 1 ATOM 11120 N N . PHE B 1 682 ? -5.037 -7.846 59.225 1.00 25.04 ? 702 PHE B N 1 ATOM 11121 C CA . PHE B 1 682 ? -4.951 -6.667 60.076 1.00 25.62 ? 702 PHE B CA 1 ATOM 11122 C C . PHE B 1 682 ? -5.283 -7.044 61.518 1.00 25.57 ? 702 PHE B C 1 ATOM 11123 O O . PHE B 1 682 ? -6.038 -7.984 61.740 1.00 26.00 ? 702 PHE B O 1 ATOM 11124 C CB . PHE B 1 682 ? -5.909 -5.585 59.580 1.00 25.61 ? 702 PHE B CB 1 ATOM 11125 C CG . PHE B 1 682 ? -5.660 -5.165 58.161 1.00 26.27 ? 702 PHE B CG 1 ATOM 11126 C CD1 . PHE B 1 682 ? -4.608 -4.320 57.850 1.00 26.36 ? 702 PHE B CD1 1 ATOM 11127 C CD2 . PHE B 1 682 ? -6.475 -5.620 57.132 1.00 26.39 ? 702 PHE B CD2 1 ATOM 11128 C CE1 . PHE B 1 682 ? -4.374 -3.928 56.541 1.00 27.19 ? 702 PHE B CE1 1 ATOM 11129 C CE2 . PHE B 1 682 ? -6.246 -5.230 55.817 1.00 26.39 ? 702 PHE B CE2 1 ATOM 11130 C CZ . PHE B 1 682 ? -5.197 -4.385 55.521 1.00 27.04 ? 702 PHE B CZ 1 ATOM 11131 N N . PRO B 1 683 ? -4.720 -6.319 62.500 1.00 25.63 ? 703 PRO B N 1 ATOM 11132 C CA . PRO B 1 683 ? -4.979 -6.619 63.914 1.00 25.63 ? 703 PRO B CA 1 ATOM 11133 C C . PRO B 1 683 ? -6.455 -6.488 64.309 1.00 25.46 ? 703 PRO B C 1 ATOM 11134 O O . PRO B 1 683 ? -6.917 -7.211 65.178 1.00 25.24 ? 703 PRO B O 1 ATOM 11135 C CB . PRO B 1 683 ? -4.145 -5.566 64.662 1.00 25.51 ? 703 PRO B CB 1 ATOM 11136 C CG . PRO B 1 683 ? -3.157 -5.084 63.696 1.00 25.80 ? 703 PRO B CG 1 ATOM 11137 C CD . PRO B 1 683 ? -3.805 -5.173 62.354 1.00 25.61 ? 703 PRO B CD 1 ATOM 11138 N N . GLU B 1 684 ? -7.164 -5.558 63.673 1.00 25.36 ? 704 GLU B N 1 ATOM 11139 C CA . GLU B 1 684 ? -8.594 -5.353 63.894 1.00 25.28 ? 704 GLU B CA 1 ATOM 11140 C C . GLU B 1 684 ? -9.179 -4.748 62.612 1.00 24.99 ? 704 GLU B C 1 ATOM 11141 O O . GLU B 1 684 ? -8.465 -4.611 61.624 1.00 24.79 ? 704 GLU B O 1 ATOM 11142 C CB . GLU B 1 684 ? -8.822 -4.447 65.106 1.00 25.47 ? 704 GLU B CB 1 ATOM 11143 C CG . GLU B 1 684 ? -7.904 -3.235 65.140 1.00 26.46 ? 704 GLU B CG 1 ATOM 11144 C CD . GLU B 1 684 ? -8.189 -2.290 66.280 1.00 26.53 ? 704 GLU B CD 1 ATOM 11145 O OE1 . GLU B 1 684 ? -8.761 -2.711 67.307 1.00 28.19 ? 704 GLU B OE1 1 ATOM 11146 O OE2 . GLU B 1 684 ? -7.834 -1.110 66.144 1.00 26.31 ? 704 GLU B OE2 1 ATOM 11147 N N . ASP B 1 685 ? -10.468 -4.418 62.613 1.00 24.62 ? 705 ASP B N 1 ATOM 11148 C CA . ASP B 1 685 ? -11.130 -3.820 61.441 1.00 24.51 ? 705 ASP B CA 1 ATOM 11149 C C . ASP B 1 685 ? -10.319 -2.650 60.856 1.00 24.34 ? 705 ASP B C 1 ATOM 11150 O O . ASP B 1 685 ? -10.214 -1.609 61.488 1.00 24.42 ? 705 ASP B O 1 ATOM 11151 C CB . ASP B 1 685 ? -12.534 -3.346 61.848 1.00 24.27 ? 705 ASP B CB 1 ATOM 11152 C CG . ASP B 1 685 ? -13.303 -2.664 60.718 1.00 24.42 ? 705 ASP B CG 1 ATOM 11153 O OD1 . ASP B 1 685 ? -12.822 -2.606 59.567 1.00 23.18 ? 705 ASP B OD1 1 ATOM 11154 O OD2 . ASP B 1 685 ? -14.424 -2.172 60.998 1.00 25.01 ? 705 ASP B OD2 1 ATOM 11155 N N . PRO B 1 686 ? -9.768 -2.805 59.635 1.00 24.49 ? 706 PRO B N 1 ATOM 11156 C CA . PRO B 1 686 ? -8.948 -1.717 59.055 1.00 24.71 ? 706 PRO B CA 1 ATOM 11157 C C . PRO B 1 686 ? -9.708 -0.430 58.709 1.00 24.65 ? 706 PRO B C 1 ATOM 11158 O O . PRO B 1 686 ? -9.075 0.602 58.516 1.00 24.74 ? 706 PRO B O 1 ATOM 11159 C CB . PRO B 1 686 ? -8.343 -2.353 57.794 1.00 24.69 ? 706 PRO B CB 1 ATOM 11160 C CG . PRO B 1 686 ? -9.227 -3.481 57.468 1.00 24.68 ? 706 PRO B CG 1 ATOM 11161 C CD . PRO B 1 686 ? -9.827 -3.978 58.745 1.00 24.59 ? 706 PRO B CD 1 ATOM 11162 N N . SER B 1 687 ? -11.043 -0.483 58.658 1.00 24.69 ? 707 SER B N 1 ATOM 11163 C CA . SER B 1 687 ? -11.870 0.722 58.469 1.00 24.54 ? 707 SER B CA 1 ATOM 11164 C C . SER B 1 687 ? -11.986 1.595 59.722 1.00 24.78 ? 707 SER B C 1 ATOM 11165 O O . SER B 1 687 ? -12.633 2.639 59.687 1.00 24.34 ? 707 SER B O 1 ATOM 11166 C CB . SER B 1 687 ? -13.291 0.356 57.998 1.00 24.72 ? 707 SER B CB 1 ATOM 11167 O OG . SER B 1 687 ? -14.098 -0.142 59.057 1.00 23.04 ? 707 SER B OG 1 ATOM 11168 N N . LEU B 1 688 ? -11.378 1.182 60.831 1.00 25.07 ? 708 LEU B N 1 ATOM 11169 C CA . LEU B 1 688 ? -11.425 1.989 62.055 1.00 25.13 ? 708 LEU B CA 1 ATOM 11170 C C . LEU B 1 688 ? -10.675 3.318 61.923 1.00 25.58 ? 708 LEU B C 1 ATOM 11171 O O . LEU B 1 688 ? -10.908 4.237 62.696 1.00 25.49 ? 708 LEU B O 1 ATOM 11172 C CB . LEU B 1 688 ? -10.898 1.195 63.246 1.00 25.24 ? 708 LEU B CB 1 ATOM 11173 C CG . LEU B 1 688 ? -11.792 0.039 63.713 1.00 24.67 ? 708 LEU B CG 1 ATOM 11174 C CD1 . LEU B 1 688 ? -11.024 -0.875 64.641 1.00 23.40 ? 708 LEU B CD1 1 ATOM 11175 C CD2 . LEU B 1 688 ? -13.066 0.560 64.378 1.00 23.11 ? 708 LEU B CD2 1 ATOM 11176 N N . ALA B 1 689 ? -9.794 3.431 60.932 1.00 25.95 ? 709 ALA B N 1 ATOM 11177 C CA . ALA B 1 689 ? -9.147 4.711 60.636 1.00 26.28 ? 709 ALA B CA 1 ATOM 11178 C C . ALA B 1 689 ? -10.104 5.762 60.030 1.00 26.63 ? 709 ALA B C 1 ATOM 11179 O O . ALA B 1 689 ? -9.809 6.961 60.071 1.00 27.09 ? 709 ALA B O 1 ATOM 11180 C CB . ALA B 1 689 ? -7.931 4.492 59.720 1.00 26.19 ? 709 ALA B CB 1 ATOM 11181 N N . SER B 1 690 ? -11.237 5.333 59.468 1.00 26.86 ? 710 SER B N 1 ATOM 11182 C CA . SER B 1 690 ? -12.171 6.267 58.836 1.00 26.76 ? 710 SER B CA 1 ATOM 11183 C C . SER B 1 690 ? -12.754 7.247 59.838 1.00 27.15 ? 710 SER B C 1 ATOM 11184 O O . SER B 1 690 ? -13.221 6.861 60.912 1.00 27.52 ? 710 SER B O 1 ATOM 11185 C CB . SER B 1 690 ? -13.318 5.533 58.134 1.00 26.84 ? 710 SER B CB 1 ATOM 11186 O OG . SER B 1 690 ? -14.299 6.453 57.660 1.00 25.61 ? 710 SER B OG 1 ATOM 11187 N N . ARG B 1 691 ? -12.751 8.519 59.471 1.00 27.47 ? 711 ARG B N 1 ATOM 11188 C CA . ARG B 1 691 ? -13.292 9.556 60.349 1.00 27.97 ? 711 ARG B CA 1 ATOM 11189 C C . ARG B 1 691 ? -14.774 9.835 60.065 1.00 27.64 ? 711 ARG B C 1 ATOM 11190 O O . ARG B 1 691 ? -15.349 10.737 60.659 1.00 28.07 ? 711 ARG B O 1 ATOM 11191 C CB . ARG B 1 691 ? -12.440 10.833 60.261 1.00 28.22 ? 711 ARG B CB 1 ATOM 11192 C CG . ARG B 1 691 ? -11.000 10.689 60.833 1.00 30.15 ? 711 ARG B CG 1 ATOM 11193 C CD . ARG B 1 691 ? -10.984 9.864 62.125 1.00 32.61 ? 711 ARG B CD 1 ATOM 11194 N NE . ARG B 1 691 ? -9.770 10.019 62.929 1.00 34.73 ? 711 ARG B NE 1 ATOM 11195 C CZ . ARG B 1 691 ? -8.686 9.245 62.867 1.00 35.69 ? 711 ARG B CZ 1 ATOM 11196 N NH1 . ARG B 1 691 ? -8.602 8.225 62.016 1.00 36.62 ? 711 ARG B NH1 1 ATOM 11197 N NH2 . ARG B 1 691 ? -7.663 9.501 63.671 1.00 36.63 ? 711 ARG B NH2 1 ATOM 11198 N N . ASP B 1 692 ? -15.389 9.018 59.207 1.00 27.35 ? 712 ASP B N 1 ATOM 11199 C CA . ASP B 1 692 ? -16.810 9.136 58.874 1.00 27.37 ? 712 ASP B CA 1 ATOM 11200 C C . ASP B 1 692 ? -17.729 8.496 59.918 1.00 26.63 ? 712 ASP B C 1 ATOM 11201 O O . ASP B 1 692 ? -18.928 8.784 59.946 1.00 26.30 ? 712 ASP B O 1 ATOM 11202 C CB . ASP B 1 692 ? -17.083 8.493 57.513 1.00 27.70 ? 712 ASP B CB 1 ATOM 11203 C CG . ASP B 1 692 ? -16.504 9.286 56.366 1.00 29.75 ? 712 ASP B CG 1 ATOM 11204 O OD1 . ASP B 1 692 ? -16.353 10.518 56.499 1.00 32.96 ? 712 ASP B OD1 1 ATOM 11205 O OD2 . ASP B 1 692 ? -16.208 8.679 55.317 1.00 32.55 ? 712 ASP B OD2 1 ATOM 11206 N N . THR B 1 693 ? -17.167 7.632 60.764 1.00 26.05 ? 713 THR B N 1 ATOM 11207 C CA . THR B 1 693 ? -17.939 6.920 61.787 1.00 25.52 ? 713 THR B CA 1 ATOM 11208 C C . THR B 1 693 ? -18.700 7.905 62.650 1.00 25.12 ? 713 THR B C 1 ATOM 11209 O O . THR B 1 693 ? -18.184 8.962 62.992 1.00 25.09 ? 713 THR B O 1 ATOM 11210 C CB . THR B 1 693 ? -17.026 6.062 62.692 1.00 25.62 ? 713 THR B CB 1 ATOM 11211 O OG1 . THR B 1 693 ? -16.334 5.101 61.892 1.00 24.64 ? 713 THR B OG1 1 ATOM 11212 C CG2 . THR B 1 693 ? -17.832 5.334 63.778 1.00 25.11 ? 713 THR B CG2 1 ATOM 11213 N N . VAL B 1 694 ? -19.938 7.557 62.977 1.00 24.56 ? 714 VAL B N 1 ATOM 11214 C CA . VAL B 1 694 ? -20.768 8.367 63.856 1.00 24.03 ? 714 VAL B CA 1 ATOM 11215 C C . VAL B 1 694 ? -21.194 7.499 65.038 1.00 23.93 ? 714 VAL B C 1 ATOM 11216 O O . VAL B 1 694 ? -21.600 6.360 64.849 1.00 23.05 ? 714 VAL B O 1 ATOM 11217 C CB . VAL B 1 694 ? -22.003 8.890 63.094 1.00 24.20 ? 714 VAL B CB 1 ATOM 11218 C CG1 . VAL B 1 694 ? -22.892 9.736 64.003 1.00 23.34 ? 714 VAL B CG1 1 ATOM 11219 C CG2 . VAL B 1 694 ? -21.563 9.675 61.852 1.00 23.53 ? 714 VAL B CG2 1 ATOM 11220 N N . ILE B 1 695 ? -21.059 8.032 66.252 1.00 23.82 ? 715 ILE B N 1 ATOM 11221 C CA . ILE B 1 695 ? -21.563 7.381 67.453 1.00 23.45 ? 715 ILE B CA 1 ATOM 11222 C C . ILE B 1 695 ? -22.524 8.334 68.179 1.00 24.09 ? 715 ILE B C 1 ATOM 11223 O O . ILE B 1 695 ? -22.187 9.504 68.458 1.00 23.70 ? 715 ILE B O 1 ATOM 11224 C CB . ILE B 1 695 ? -20.426 6.934 68.404 1.00 23.36 ? 715 ILE B CB 1 ATOM 11225 C CG1 . ILE B 1 695 ? -19.277 6.285 67.612 1.00 23.20 ? 715 ILE B CG1 1 ATOM 11226 C CG2 . ILE B 1 695 ? -20.967 5.944 69.451 1.00 23.09 ? 715 ILE B CG2 1 ATOM 11227 C CD1 . ILE B 1 695 ? -18.189 5.673 68.462 1.00 21.93 ? 715 ILE B CD1 1 ATOM 11228 N N . VAL B 1 696 ? -23.724 7.833 68.473 1.00 24.12 ? 716 VAL B N 1 ATOM 11229 C CA . VAL B 1 696 ? -24.723 8.590 69.210 1.00 24.59 ? 716 VAL B CA 1 ATOM 11230 C C . VAL B 1 696 ? -24.798 8.046 70.639 1.00 25.38 ? 716 VAL B C 1 ATOM 11231 O O . VAL B 1 696 ? -25.059 6.859 70.838 1.00 25.01 ? 716 VAL B O 1 ATOM 11232 C CB . VAL B 1 696 ? -26.125 8.504 68.549 1.00 24.68 ? 716 VAL B CB 1 ATOM 11233 C CG1 . VAL B 1 696 ? -27.128 9.348 69.312 1.00 23.61 ? 716 VAL B CG1 1 ATOM 11234 C CG2 . VAL B 1 696 ? -26.076 8.955 67.090 1.00 24.45 ? 716 VAL B CG2 1 ATOM 11235 N N . TRP B 1 697 ? -24.574 8.921 71.621 1.00 26.35 ? 717 TRP B N 1 ATOM 11236 C CA . TRP B 1 697 ? -24.598 8.551 73.036 1.00 27.44 ? 717 TRP B CA 1 ATOM 11237 C C . TRP B 1 697 ? -25.755 9.218 73.769 1.00 28.51 ? 717 TRP B C 1 ATOM 11238 O O . TRP B 1 697 ? -26.083 10.364 73.491 1.00 28.92 ? 717 TRP B O 1 ATOM 11239 C CB . TRP B 1 697 ? -23.305 8.983 73.728 1.00 27.27 ? 717 TRP B CB 1 ATOM 11240 C CG . TRP B 1 697 ? -22.060 8.530 73.073 1.00 26.60 ? 717 TRP B CG 1 ATOM 11241 C CD1 . TRP B 1 697 ? -21.353 9.193 72.122 1.00 26.14 ? 717 TRP B CD1 1 ATOM 11242 C CD2 . TRP B 1 697 ? -21.340 7.323 73.345 1.00 26.44 ? 717 TRP B CD2 1 ATOM 11243 N NE1 . TRP B 1 697 ? -20.236 8.471 71.771 1.00 25.74 ? 717 TRP B NE1 1 ATOM 11244 C CE2 . TRP B 1 697 ? -20.210 7.314 72.504 1.00 25.75 ? 717 TRP B CE2 1 ATOM 11245 C CE3 . TRP B 1 697 ? -21.551 6.241 74.205 1.00 26.81 ? 717 TRP B CE3 1 ATOM 11246 C CZ2 . TRP B 1 697 ? -19.292 6.272 72.501 1.00 26.01 ? 717 TRP B CZ2 1 ATOM 11247 C CZ3 . TRP B 1 697 ? -20.639 5.206 74.203 1.00 26.59 ? 717 TRP B CZ3 1 ATOM 11248 C CH2 . TRP B 1 697 ? -19.522 5.227 73.356 1.00 26.37 ? 717 TRP B CH2 1 ATOM 11249 N N . PRO B 1 698 ? -26.354 8.518 74.741 1.00 30.21 ? 718 PRO B N 1 ATOM 11250 C CA . PRO B 1 698 ? -27.370 9.145 75.569 1.00 31.69 ? 718 PRO B CA 1 ATOM 11251 C C . PRO B 1 698 ? -26.755 10.095 76.601 1.00 33.18 ? 718 PRO B C 1 ATOM 11252 O O . PRO B 1 698 ? -25.597 9.937 76.977 1.00 33.24 ? 718 PRO B O 1 ATOM 11253 C CB . PRO B 1 698 ? -28.019 7.950 76.263 1.00 31.47 ? 718 PRO B CB 1 ATOM 11254 C CG . PRO B 1 698 ? -26.888 7.012 76.448 1.00 30.95 ? 718 PRO B CG 1 ATOM 11255 C CD . PRO B 1 698 ? -26.051 7.155 75.203 1.00 30.06 ? 718 PRO B CD 1 ATOM 11256 N N . ARG B 1 699 ? -27.534 11.073 77.041 1.00 35.28 ? 719 ARG B N 1 ATOM 11257 C CA . ARG B 1 699 ? -27.104 12.025 78.070 1.00 37.14 ? 719 ARG B CA 1 ATOM 11258 C C . ARG B 1 699 ? -28.206 12.168 79.108 1.00 38.20 ? 719 ARG B C 1 ATOM 11259 O O . ARG B 1 699 ? -29.380 12.317 78.751 1.00 38.51 ? 719 ARG B O 1 ATOM 11260 C CB . ARG B 1 699 ? -26.805 13.393 77.446 1.00 37.34 ? 719 ARG B CB 1 ATOM 11261 C CG . ARG B 1 699 ? -25.528 13.438 76.637 1.00 38.39 ? 719 ARG B CG 1 ATOM 11262 C CD . ARG B 1 699 ? -24.326 13.567 77.536 1.00 40.49 ? 719 ARG B CD 1 ATOM 11263 N NE . ARG B 1 699 ? -23.069 13.237 76.859 1.00 42.44 ? 719 ARG B NE 1 ATOM 11264 C CZ . ARG B 1 699 ? -22.599 12.001 76.665 1.00 43.55 ? 719 ARG B CZ 1 ATOM 11265 N NH1 . ARG B 1 699 ? -23.277 10.932 77.072 1.00 43.96 ? 719 ARG B NH1 1 ATOM 11266 N NH2 . ARG B 1 699 ? -21.435 11.829 76.049 1.00 44.58 ? 719 ARG B NH2 1 ATOM 11267 N N . ASP B 1 700 ? -27.834 12.120 80.384 1.00 39.71 ? 720 ASP B N 1 ATOM 11268 C CA . ASP B 1 700 ? -28.806 12.272 81.476 1.00 40.85 ? 720 ASP B CA 1 ATOM 11269 C C . ASP B 1 700 ? -29.532 13.610 81.381 1.00 41.07 ? 720 ASP B C 1 ATOM 11270 O O . ASP B 1 700 ? -28.901 14.664 81.405 1.00 41.42 ? 720 ASP B O 1 ATOM 11271 C CB . ASP B 1 700 ? -28.115 12.184 82.838 1.00 41.34 ? 720 ASP B CB 1 ATOM 11272 C CG . ASP B 1 700 ? -27.509 10.821 83.102 1.00 43.10 ? 720 ASP B CG 1 ATOM 11273 O OD1 . ASP B 1 700 ? -28.058 9.811 82.605 1.00 46.26 ? 720 ASP B OD1 1 ATOM 11274 O OD2 . ASP B 1 700 ? -26.483 10.757 83.818 1.00 45.88 ? 720 ASP B OD2 1 ATOM 11275 N N . ASN B 1 701 ? -30.854 13.553 81.242 1.00 41.38 ? 721 ASN B N 1 ATOM 11276 C CA . ASN B 1 701 ? -31.711 14.742 81.293 1.00 41.61 ? 721 ASN B CA 1 ATOM 11277 C C . ASN B 1 701 ? -31.445 15.781 80.202 1.00 41.55 ? 721 ASN B C 1 ATOM 11278 O O . ASN B 1 701 ? -31.724 16.973 80.402 1.00 42.01 ? 721 ASN B O 1 ATOM 11279 C CB . ASN B 1 701 ? -31.619 15.410 82.676 1.00 41.54 ? 721 ASN B CB 1 ATOM 11280 N N . GLY B 1 702 ? -30.927 15.330 79.056 1.00 40.82 ? 722 GLY B N 1 ATOM 11281 C CA . GLY B 1 702 ? -30.659 16.207 77.912 1.00 40.06 ? 722 GLY B CA 1 ATOM 11282 C C . GLY B 1 702 ? -30.699 15.455 76.588 1.00 39.50 ? 722 GLY B C 1 ATOM 11283 O O . GLY B 1 702 ? -30.909 14.240 76.568 1.00 39.67 ? 722 GLY B O 1 ATOM 11284 N N . PRO B 1 703 ? -30.511 16.171 75.465 1.00 38.25 ? 723 PRO B N 1 ATOM 11285 C CA . PRO B 1 703 ? -30.463 15.502 74.163 1.00 37.29 ? 723 PRO B CA 1 ATOM 11286 C C . PRO B 1 703 ? -29.210 14.648 74.007 1.00 35.99 ? 723 PRO B C 1 ATOM 11287 O O . PRO B 1 703 ? -28.245 14.823 74.757 1.00 35.89 ? 723 PRO B O 1 ATOM 11288 C CB . PRO B 1 703 ? -30.458 16.661 73.150 1.00 37.40 ? 723 PRO B CB 1 ATOM 11289 C CG . PRO B 1 703 ? -30.805 17.899 73.940 1.00 38.01 ? 723 PRO B CG 1 ATOM 11290 C CD . PRO B 1 703 ? -30.358 17.631 75.341 1.00 38.54 ? 723 PRO B CD 1 ATOM 11291 N N . ASN B 1 704 ? -29.235 13.729 73.044 1.00 34.26 ? 724 ASN B N 1 ATOM 11292 C CA . ASN B 1 704 ? -28.108 12.828 72.816 1.00 32.99 ? 724 ASN B CA 1 ATOM 11293 C C . ASN B 1 704 ? -26.897 13.587 72.314 1.00 32.03 ? 724 ASN B C 1 ATOM 11294 O O . ASN B 1 704 ? -27.038 14.608 71.660 1.00 31.66 ? 724 ASN B O 1 ATOM 11295 C CB . ASN B 1 704 ? -28.461 11.745 71.788 1.00 32.79 ? 724 ASN B CB 1 ATOM 11296 C CG . ASN B 1 704 ? -29.560 10.827 72.259 1.00 31.96 ? 724 ASN B CG 1 ATOM 11297 O OD1 . ASN B 1 704 ? -30.453 10.485 71.493 1.00 32.04 ? 724 ASN B OD1 1 ATOM 11298 N ND2 . ASN B 1 704 ? -29.511 10.433 73.520 1.00 27.71 ? 724 ASN B ND2 1 ATOM 11299 N N . TYR B 1 705 ? -25.716 13.071 72.632 1.00 31.04 ? 725 TYR B N 1 ATOM 11300 C CA . TYR B 1 705 ? -24.471 13.568 72.070 1.00 30.54 ? 725 TYR B CA 1 ATOM 11301 C C . TYR B 1 705 ? -24.185 12.812 70.775 1.00 29.81 ? 725 TYR B C 1 ATOM 11302 O O . TYR B 1 705 ? -24.005 11.599 70.793 1.00 29.61 ? 725 TYR B O 1 ATOM 11303 C CB . TYR B 1 705 ? -23.325 13.363 73.068 1.00 30.34 ? 725 TYR B CB 1 ATOM 11304 C CG . TYR B 1 705 ? -21.959 13.707 72.529 1.00 31.50 ? 725 TYR B CG 1 ATOM 11305 C CD1 . TYR B 1 705 ? -21.744 14.883 71.811 1.00 33.00 ? 725 TYR B CD1 1 ATOM 11306 C CD2 . TYR B 1 705 ? -20.872 12.865 72.748 1.00 32.20 ? 725 TYR B CD2 1 ATOM 11307 C CE1 . TYR B 1 705 ? -20.484 15.204 71.315 1.00 33.73 ? 725 TYR B CE1 1 ATOM 11308 C CE2 . TYR B 1 705 ? -19.612 13.181 72.256 1.00 33.04 ? 725 TYR B CE2 1 ATOM 11309 C CZ . TYR B 1 705 ? -19.427 14.349 71.542 1.00 33.58 ? 725 TYR B CZ 1 ATOM 11310 O OH . TYR B 1 705 ? -18.182 14.668 71.058 1.00 35.77 ? 725 TYR B OH 1 ATOM 11311 N N . VAL B 1 706 ? -24.170 13.527 69.656 1.00 29.38 ? 726 VAL B N 1 ATOM 11312 C CA . VAL B 1 706 ? -23.826 12.937 68.373 1.00 29.05 ? 726 VAL B CA 1 ATOM 11313 C C . VAL B 1 706 ? -22.348 13.188 68.088 1.00 29.11 ? 726 VAL B C 1 ATOM 11314 O O . VAL B 1 706 ? -21.969 14.265 67.642 1.00 29.11 ? 726 VAL B O 1 ATOM 11315 C CB . VAL B 1 706 ? -24.680 13.509 67.231 1.00 29.08 ? 726 VAL B CB 1 ATOM 11316 C CG1 . VAL B 1 706 ? -24.259 12.880 65.903 1.00 28.52 ? 726 VAL B CG1 1 ATOM 11317 C CG2 . VAL B 1 706 ? -26.161 13.281 67.508 1.00 27.91 ? 726 VAL B CG2 1 ATOM 11318 N N . GLN B 1 707 ? -21.519 12.185 68.357 1.00 29.46 ? 727 GLN B N 1 ATOM 11319 C CA . GLN B 1 707 ? -20.075 12.313 68.210 1.00 29.95 ? 727 GLN B CA 1 ATOM 11320 C C . GLN B 1 707 ? -19.672 12.075 66.758 1.00 30.70 ? 727 GLN B C 1 ATOM 11321 O O . GLN B 1 707 ? -20.019 11.053 66.173 1.00 31.08 ? 727 GLN B O 1 ATOM 11322 C CB . GLN B 1 707 ? -19.355 11.325 69.128 1.00 29.80 ? 727 GLN B CB 1 ATOM 11323 C CG . GLN B 1 707 ? -17.839 11.473 69.125 1.00 29.56 ? 727 GLN B CG 1 ATOM 11324 C CD . GLN B 1 707 ? -17.152 10.668 70.212 1.00 29.60 ? 727 GLN B CD 1 ATOM 11325 O OE1 . GLN B 1 707 ? -17.659 9.643 70.665 1.00 30.23 ? 727 GLN B OE1 1 ATOM 11326 N NE2 . GLN B 1 707 ? -15.974 11.125 70.627 1.00 30.98 ? 727 GLN B NE2 1 ATOM 11327 N N . ARG B 1 708 ? -18.940 13.030 66.190 1.00 31.45 ? 728 ARG B N 1 ATOM 11328 C CA . ARG B 1 708 ? -18.454 12.962 64.814 1.00 31.87 ? 728 ARG B CA 1 ATOM 11329 C C . ARG B 1 708 ? -16.972 13.313 64.783 1.00 32.47 ? 728 ARG B C 1 ATOM 11330 O O . ARG B 1 708 ? -16.454 13.922 65.718 1.00 32.48 ? 728 ARG B O 1 ATOM 11331 C CB . ARG B 1 708 ? -19.192 13.975 63.950 1.00 31.84 ? 728 ARG B CB 1 ATOM 11332 C CG . ARG B 1 708 ? -20.708 13.900 64.010 1.00 32.15 ? 728 ARG B CG 1 ATOM 11333 C CD . ARG B 1 708 ? -21.325 15.046 63.224 1.00 31.76 ? 728 ARG B CD 1 ATOM 11334 N NE . ARG B 1 708 ? -22.749 14.840 62.966 1.00 31.87 ? 728 ARG B NE 1 ATOM 11335 C CZ . ARG B 1 708 ? -23.247 14.116 61.966 1.00 32.13 ? 728 ARG B CZ 1 ATOM 11336 N NH1 . ARG B 1 708 ? -22.438 13.505 61.105 1.00 31.93 ? 728 ARG B NH1 1 ATOM 11337 N NH2 . ARG B 1 708 ? -24.569 14.007 61.822 1.00 33.02 ? 728 ARG B NH2 1 ATOM 11338 N N . TRP B 1 709 ? -16.297 12.927 63.704 1.00 32.90 ? 729 TRP B N 1 ATOM 11339 C CA . TRP B 1 709 ? -14.904 13.310 63.469 1.00 33.00 ? 729 TRP B CA 1 ATOM 11340 C C . TRP B 1 709 ? -14.729 14.050 62.132 1.00 33.81 ? 729 TRP B C 1 ATOM 11341 O O . TRP B 1 709 ? -13.611 14.385 61.741 1.00 33.66 ? 729 TRP B O 1 ATOM 11342 C CB . TRP B 1 709 ? -14.012 12.071 63.531 1.00 32.79 ? 729 TRP B CB 1 ATOM 11343 C CG . TRP B 1 709 ? -13.906 11.511 64.910 1.00 31.76 ? 729 TRP B CG 1 ATOM 11344 C CD1 . TRP B 1 709 ? -12.908 11.741 65.813 1.00 31.19 ? 729 TRP B CD1 1 ATOM 11345 C CD2 . TRP B 1 709 ? -14.844 10.644 65.562 1.00 31.28 ? 729 TRP B CD2 1 ATOM 11346 N NE1 . TRP B 1 709 ? -13.161 11.067 66.979 1.00 30.74 ? 729 TRP B NE1 1 ATOM 11347 C CE2 . TRP B 1 709 ? -14.343 10.386 66.855 1.00 30.89 ? 729 TRP B CE2 1 ATOM 11348 C CE3 . TRP B 1 709 ? -16.056 10.057 65.176 1.00 30.71 ? 729 TRP B CE3 1 ATOM 11349 C CZ2 . TRP B 1 709 ? -15.016 9.566 67.770 1.00 31.13 ? 729 TRP B CZ2 1 ATOM 11350 C CZ3 . TRP B 1 709 ? -16.723 9.242 66.080 1.00 30.74 ? 729 TRP B CZ3 1 ATOM 11351 C CH2 . TRP B 1 709 ? -16.201 9.003 67.365 1.00 31.36 ? 729 TRP B CH2 1 ATOM 11352 N N . ILE B 1 710 ? -15.844 14.264 61.433 1.00 34.46 ? 730 ILE B N 1 ATOM 11353 C CA . ILE B 1 710 ? -15.934 15.140 60.270 1.00 35.03 ? 730 ILE B CA 1 ATOM 11354 C C . ILE B 1 710 ? -17.276 15.870 60.427 1.00 35.08 ? 730 ILE B C 1 ATOM 11355 O O . ILE B 1 710 ? -18.252 15.270 60.877 1.00 35.22 ? 730 ILE B O 1 ATOM 11356 C CB . ILE B 1 710 ? -15.880 14.348 58.930 1.00 35.35 ? 730 ILE B CB 1 ATOM 11357 C CG1 . ILE B 1 710 ? -14.510 13.680 58.757 1.00 36.28 ? 730 ILE B CG1 1 ATOM 11358 C CG2 . ILE B 1 710 ? -16.149 15.264 57.730 1.00 35.45 ? 730 ILE B CG2 1 ATOM 11359 C CD1 . ILE B 1 710 ? -14.300 13.008 57.385 1.00 37.46 ? 730 ILE B CD1 1 ATOM 11360 N N . PRO B 1 711 ? -17.334 17.171 60.098 1.00 35.34 ? 731 PRO B N 1 ATOM 11361 C CA . PRO B 1 711 ? -18.598 17.876 60.342 1.00 35.26 ? 731 PRO B CA 1 ATOM 11362 C C . PRO B 1 711 ? -19.731 17.336 59.483 1.00 35.26 ? 731 PRO B C 1 ATOM 11363 O O . PRO B 1 711 ? -19.483 16.845 58.380 1.00 35.00 ? 731 PRO B O 1 ATOM 11364 C CB . PRO B 1 711 ? -18.285 19.325 59.953 1.00 35.30 ? 731 PRO B CB 1 ATOM 11365 C CG . PRO B 1 711 ? -16.789 19.417 59.906 1.00 35.54 ? 731 PRO B CG 1 ATOM 11366 C CD . PRO B 1 711 ? -16.303 18.061 59.533 1.00 35.58 ? 731 PRO B CD 1 ATOM 11367 N N . GLU B 1 712 ? -20.957 17.418 59.992 1.00 35.27 ? 732 GLU B N 1 ATOM 11368 C CA . GLU B 1 712 ? -22.127 17.049 59.211 1.00 35.57 ? 732 GLU B CA 1 ATOM 11369 C C . GLU B 1 712 ? -22.141 17.879 57.936 1.00 36.18 ? 732 GLU B C 1 ATOM 11370 O O . GLU B 1 712 ? -21.821 19.064 57.951 1.00 36.64 ? 732 GLU B O 1 ATOM 11371 C CB . GLU B 1 712 ? -23.424 17.268 59.999 1.00 35.36 ? 732 GLU B CB 1 ATOM 11372 C CG . GLU B 1 712 ? -24.684 16.884 59.220 1.00 34.18 ? 732 GLU B CG 1 ATOM 11373 C CD . GLU B 1 712 ? -25.967 16.957 60.039 1.00 32.89 ? 732 GLU B CD 1 ATOM 11374 O OE1 . GLU B 1 712 ? -25.929 17.331 61.229 1.00 31.50 ? 732 GLU B OE1 1 ATOM 11375 O OE2 . GLU B 1 712 ? -27.030 16.624 59.478 1.00 32.17 ? 732 GLU B OE2 1 ATOM 11376 N N . ASP B 1 713 ? -22.480 17.248 56.826 1.00 36.82 ? 733 ASP B N 1 ATOM 11377 C CA . ASP B 1 713 ? -22.504 17.937 55.550 1.00 37.45 ? 733 ASP B CA 1 ATOM 11378 C C . ASP B 1 713 ? -23.873 17.768 54.923 1.00 37.46 ? 733 ASP B C 1 ATOM 11379 O O . ASP B 1 713 ? -24.377 16.653 54.841 1.00 37.38 ? 733 ASP B O 1 ATOM 11380 C CB . ASP B 1 713 ? -21.436 17.362 54.621 1.00 37.58 ? 733 ASP B CB 1 ATOM 11381 C CG . ASP B 1 713 ? -21.680 17.716 53.171 1.00 38.87 ? 733 ASP B CG 1 ATOM 11382 O OD1 . ASP B 1 713 ? -21.827 18.917 52.870 1.00 40.47 ? 733 ASP B OD1 1 ATOM 11383 O OD2 . ASP B 1 713 ? -21.739 16.794 52.328 1.00 41.44 ? 733 ASP B OD2 1 ATOM 11384 N N . ARG B 1 714 ? -24.462 18.875 54.481 1.00 37.66 ? 734 ARG B N 1 ATOM 11385 C CA . ARG B 1 714 ? -25.724 18.837 53.741 1.00 37.84 ? 734 ARG B CA 1 ATOM 11386 C C . ARG B 1 714 ? -25.648 19.658 52.448 1.00 37.44 ? 734 ARG B C 1 ATOM 11387 O O . ARG B 1 714 ? -26.677 19.964 51.846 1.00 37.41 ? 734 ARG B O 1 ATOM 11388 C CB . ARG B 1 714 ? -26.867 19.345 54.625 1.00 38.16 ? 734 ARG B CB 1 ATOM 11389 C CG . ARG B 1 714 ? -27.027 18.602 55.960 1.00 39.66 ? 734 ARG B CG 1 ATOM 11390 C CD . ARG B 1 714 ? -27.772 19.472 56.980 1.00 41.36 ? 734 ARG B CD 1 ATOM 11391 N NE . ARG B 1 714 ? -29.102 19.826 56.495 1.00 42.73 ? 734 ARG B NE 1 ATOM 11392 C CZ . ARG B 1 714 ? -29.783 20.917 56.842 1.00 44.46 ? 734 ARG B CZ 1 ATOM 11393 N NH1 . ARG B 1 714 ? -29.274 21.804 57.690 1.00 45.50 ? 734 ARG B NH1 1 ATOM 11394 N NH2 . ARG B 1 714 ? -30.991 21.128 56.330 1.00 45.51 ? 734 ARG B NH2 1 ATOM 11395 N N . ASP B 1 715 ? -24.432 19.998 52.016 1.00 37.33 ? 735 ASP B N 1 ATOM 11396 C CA . ASP B 1 715 ? -24.233 20.811 50.815 1.00 37.17 ? 735 ASP B CA 1 ATOM 11397 C C . ASP B 1 715 ? -24.661 20.070 49.560 1.00 36.84 ? 735 ASP B C 1 ATOM 11398 O O . ASP B 1 715 ? -24.489 18.859 49.449 1.00 36.20 ? 735 ASP B O 1 ATOM 11399 C CB . ASP B 1 715 ? -22.764 21.209 50.648 1.00 37.36 ? 735 ASP B CB 1 ATOM 11400 C CG . ASP B 1 715 ? -22.297 22.183 51.703 1.00 37.80 ? 735 ASP B CG 1 ATOM 11401 O OD1 . ASP B 1 715 ? -23.121 22.601 52.544 1.00 38.37 ? 735 ASP B OD1 1 ATOM 11402 O OD2 . ASP B 1 715 ? -21.100 22.535 51.680 1.00 38.47 ? 735 ASP B OD2 1 ATOM 11403 N N . CYS B 1 716 ? -25.218 20.821 48.618 1.00 36.74 ? 736 CYS B N 1 ATOM 11404 C CA . CYS B 1 716 ? -25.591 20.281 47.327 1.00 36.84 ? 736 CYS B CA 1 ATOM 11405 C C . CYS B 1 716 ? -24.886 21.096 46.265 1.00 36.99 ? 736 CYS B C 1 ATOM 11406 O O . CYS B 1 716 ? -24.654 22.282 46.460 1.00 37.14 ? 736 CYS B O 1 ATOM 11407 C CB . CYS B 1 716 ? -27.103 20.349 47.129 1.00 36.57 ? 736 CYS B CB 1 ATOM 11408 S SG . CYS B 1 716 ? -27.633 19.480 45.648 1.00 36.30 ? 736 CYS B SG 1 ATOM 11409 N N . SER B 1 717 ? -24.529 20.451 45.157 1.00 36.94 ? 737 SER B N 1 ATOM 11410 C CA . SER B 1 717 ? -23.975 21.147 43.998 1.00 37.10 ? 737 SER B CA 1 ATOM 11411 C C . SER B 1 717 ? -24.402 20.444 42.713 1.00 37.26 ? 737 SER B C 1 ATOM 11412 O O . SER B 1 717 ? -24.878 19.308 42.747 1.00 37.37 ? 737 SER B O 1 ATOM 11413 C CB . SER B 1 717 ? -22.446 21.205 44.079 1.00 37.12 ? 737 SER B CB 1 ATOM 11414 O OG . SER B 1 717 ? -21.880 19.915 43.932 1.00 36.81 ? 737 SER B OG 1 ATOM 11415 N N . MET B 1 718 ? -24.215 21.119 41.584 1.00 37.58 ? 738 MET B N 1 ATOM 11416 C CA . MET B 1 718 ? -24.584 20.575 40.281 1.00 37.72 ? 738 MET B CA 1 ATOM 11417 C C . MET B 1 718 ? -23.390 19.931 39.601 1.00 37.19 ? 738 MET B C 1 ATOM 11418 O O . MET B 1 718 ? -22.258 20.406 39.743 1.00 37.53 ? 738 MET B O 1 ATOM 11419 C CB . MET B 1 718 ? -25.092 21.672 39.362 1.00 38.32 ? 738 MET B CB 1 ATOM 11420 C CG . MET B 1 718 ? -26.155 22.558 39.941 1.00 40.44 ? 738 MET B CG 1 ATOM 11421 S SD . MET B 1 718 ? -26.578 23.803 38.709 1.00 46.81 ? 738 MET B SD 1 ATOM 11422 C CE . MET B 1 718 ? -25.094 24.835 38.693 1.00 45.00 ? 738 MET B CE 1 ATOM 11423 N N . PRO B 1 719 ? -23.633 18.861 38.833 1.00 36.31 ? 739 PRO B N 1 ATOM 11424 C CA . PRO B 1 719 ? -22.554 18.287 38.053 1.00 35.66 ? 739 PRO B CA 1 ATOM 11425 C C . PRO B 1 719 ? -22.454 18.994 36.705 1.00 34.65 ? 739 PRO B C 1 ATOM 11426 O O . PRO B 1 719 ? -23.322 19.806 36.376 1.00 34.15 ? 739 PRO B O 1 ATOM 11427 C CB . PRO B 1 719 ? -23.005 16.838 37.872 1.00 35.71 ? 739 PRO B CB 1 ATOM 11428 C CG . PRO B 1 719 ? -24.513 16.937 37.805 1.00 36.26 ? 739 PRO B CG 1 ATOM 11429 C CD . PRO B 1 719 ? -24.918 18.184 38.567 1.00 36.49 ? 739 PRO B CD 1 ATOM 11430 N N . PRO B 1 720 ? -21.401 18.691 35.927 1.00 33.88 ? 740 PRO B N 1 ATOM 11431 C CA . PRO B 1 720 ? -21.332 19.160 34.552 1.00 33.44 ? 740 PRO B CA 1 ATOM 11432 C C . PRO B 1 720 ? -22.614 18.832 33.796 1.00 32.52 ? 740 PRO B C 1 ATOM 11433 O O . PRO B 1 720 ? -23.223 17.802 34.056 1.00 32.34 ? 740 PRO B O 1 ATOM 11434 C CB . PRO B 1 720 ? -20.163 18.361 33.968 1.00 33.69 ? 740 PRO B CB 1 ATOM 11435 C CG . PRO B 1 720 ? -19.269 18.102 35.136 1.00 33.89 ? 740 PRO B CG 1 ATOM 11436 C CD . PRO B 1 720 ? -20.188 17.949 36.321 1.00 34.21 ? 740 PRO B CD 1 ATOM 11437 N N . PRO B 1 721 ? -23.036 19.707 32.877 1.00 31.62 ? 741 PRO B N 1 ATOM 11438 C CA . PRO B 1 721 ? -24.166 19.348 32.028 1.00 30.83 ? 741 PRO B CA 1 ATOM 11439 C C . PRO B 1 721 ? -23.828 18.121 31.179 1.00 29.81 ? 741 PRO B C 1 ATOM 11440 O O . PRO B 1 721 ? -22.653 17.878 30.882 1.00 29.60 ? 741 PRO B O 1 ATOM 11441 C CB . PRO B 1 721 ? -24.346 20.577 31.139 1.00 31.00 ? 741 PRO B CB 1 ATOM 11442 C CG . PRO B 1 721 ? -23.579 21.679 31.816 1.00 31.48 ? 741 PRO B CG 1 ATOM 11443 C CD . PRO B 1 721 ? -22.471 21.019 32.525 1.00 31.98 ? 741 PRO B CD 1 ATOM 11444 N N . PHE B 1 722 ? -24.842 17.353 30.800 1.00 28.67 ? 742 PHE B N 1 ATOM 11445 C CA . PHE B 1 722 ? -24.609 16.148 30.024 1.00 27.73 ? 742 PHE B CA 1 ATOM 11446 C C . PHE B 1 722 ? -24.011 16.502 28.674 1.00 27.33 ? 742 PHE B C 1 ATOM 11447 O O . PHE B 1 722 ? -24.452 17.444 28.025 1.00 27.19 ? 742 PHE B O 1 ATOM 11448 C CB . PHE B 1 722 ? -25.905 15.379 29.792 1.00 27.58 ? 742 PHE B CB 1 ATOM 11449 C CG . PHE B 1 722 ? -25.715 14.122 28.994 1.00 26.72 ? 742 PHE B CG 1 ATOM 11450 C CD1 . PHE B 1 722 ? -25.301 12.947 29.619 1.00 25.84 ? 742 PHE B CD1 1 ATOM 11451 C CD2 . PHE B 1 722 ? -25.911 14.116 27.624 1.00 26.17 ? 742 PHE B CD2 1 ATOM 11452 C CE1 . PHE B 1 722 ? -25.121 11.783 28.890 1.00 25.99 ? 742 PHE B CE1 1 ATOM 11453 C CE2 . PHE B 1 722 ? -25.737 12.950 26.886 1.00 26.11 ? 742 PHE B CE2 1 ATOM 11454 C CZ . PHE B 1 722 ? -25.337 11.785 27.521 1.00 26.10 ? 742 PHE B CZ 1 ATOM 11455 N N . SER B 1 723 ? -23.003 15.749 28.261 1.00 26.72 ? 743 SER B N 1 ATOM 11456 C CA . SER B 1 723 ? -22.534 15.801 26.884 1.00 26.53 ? 743 SER B CA 1 ATOM 11457 C C . SER B 1 723 ? -22.065 14.416 26.472 1.00 26.24 ? 743 SER B C 1 ATOM 11458 O O . SER B 1 723 ? -21.721 13.596 27.320 1.00 25.90 ? 743 SER B O 1 ATOM 11459 C CB . SER B 1 723 ? -21.394 16.805 26.720 1.00 26.48 ? 743 SER B CB 1 ATOM 11460 O OG . SER B 1 723 ? -20.183 16.280 27.240 1.00 26.77 ? 743 SER B OG 1 ATOM 11461 N N . TYR B 1 724 ? -22.059 14.173 25.165 1.00 26.44 ? 744 TYR B N 1 ATOM 11462 C CA . TYR B 1 724 ? -21.594 12.908 24.595 1.00 26.09 ? 744 TYR B CA 1 ATOM 11463 C C . TYR B 1 724 ? -21.089 13.177 23.188 1.00 25.99 ? 744 TYR B C 1 ATOM 11464 O O . TYR B 1 724 ? -21.751 13.854 22.403 1.00 26.48 ? 744 TYR B O 1 ATOM 11465 C CB . TYR B 1 724 ? -22.731 11.895 24.564 1.00 25.97 ? 744 TYR B CB 1 ATOM 11466 C CG . TYR B 1 724 ? -22.278 10.464 24.437 1.00 25.01 ? 744 TYR B CG 1 ATOM 11467 C CD1 . TYR B 1 724 ? -21.890 9.748 25.556 1.00 24.36 ? 744 TYR B CD1 1 ATOM 11468 C CD2 . TYR B 1 724 ? -22.237 9.828 23.201 1.00 24.41 ? 744 TYR B CD2 1 ATOM 11469 C CE1 . TYR B 1 724 ? -21.466 8.430 25.459 1.00 25.11 ? 744 TYR B CE1 1 ATOM 11470 C CE2 . TYR B 1 724 ? -21.809 8.498 23.086 1.00 24.82 ? 744 TYR B CE2 1 ATOM 11471 C CZ . TYR B 1 724 ? -21.426 7.809 24.223 1.00 24.67 ? 744 TYR B CZ 1 ATOM 11472 O OH . TYR B 1 724 ? -21.021 6.509 24.146 1.00 22.07 ? 744 TYR B OH 1 ATOM 11473 N N . ASN B 1 725 ? -19.908 12.659 22.880 1.00 25.68 ? 745 ASN B N 1 ATOM 11474 C CA . ASN B 1 725 ? -19.273 12.903 21.601 1.00 25.51 ? 745 ASN B CA 1 ATOM 11475 C C . ASN B 1 725 ? -19.550 11.783 20.599 1.00 24.80 ? 745 ASN B C 1 ATOM 11476 O O . ASN B 1 725 ? -20.104 12.023 19.527 1.00 24.36 ? 745 ASN B O 1 ATOM 11477 C CB . ASN B 1 725 ? -17.772 13.054 21.793 1.00 26.01 ? 745 ASN B CB 1 ATOM 11478 C CG . ASN B 1 725 ? -17.091 13.515 20.544 1.00 27.47 ? 745 ASN B CG 1 ATOM 11479 O OD1 . ASN B 1 725 ? -16.741 12.721 19.674 1.00 29.20 ? 745 ASN B OD1 1 ATOM 11480 N ND2 . ASN B 1 725 ? -16.913 14.819 20.438 1.00 31.34 ? 745 ASN B ND2 1 ATOM 11481 N N . GLY B 1 726 ? -19.146 10.566 20.957 1.00 24.12 ? 746 GLY B N 1 ATOM 11482 C CA . GLY B 1 726 ? -19.416 9.387 20.155 1.00 23.68 ? 746 GLY B CA 1 ATOM 11483 C C . GLY B 1 726 ? -18.397 9.087 19.071 1.00 23.47 ? 746 GLY B C 1 ATOM 11484 O O . GLY B 1 726 ? -18.496 8.049 18.426 1.00 23.34 ? 746 GLY B O 1 ATOM 11485 N N . THR B 1 727 ? -17.432 9.981 18.856 1.00 23.06 ? 747 THR B N 1 ATOM 11486 C CA . THR B 1 727 ? -16.348 9.715 17.911 1.00 22.97 ? 747 THR B CA 1 ATOM 11487 C C . THR B 1 727 ? -15.056 9.405 18.645 1.00 23.52 ? 747 THR B C 1 ATOM 11488 O O . THR B 1 727 ? -14.865 9.804 19.795 1.00 23.37 ? 747 THR B O 1 ATOM 11489 C CB . THR B 1 727 ? -16.094 10.886 16.922 1.00 22.72 ? 747 THR B CB 1 ATOM 11490 O OG1 . THR B 1 727 ? -15.444 11.969 17.603 1.00 22.31 ? 747 THR B OG1 1 ATOM 11491 C CG2 . THR B 1 727 ? -17.399 11.359 16.269 1.00 21.55 ? 747 THR B CG2 1 ATOM 11492 N N . TYR B 1 728 ? -14.182 8.681 17.954 1.00 24.34 ? 748 TYR B N 1 ATOM 11493 C CA . TYR B 1 728 ? -12.883 8.250 18.474 1.00 25.21 ? 748 TYR B CA 1 ATOM 11494 C C . TYR B 1 728 ? -11.945 8.354 17.269 1.00 26.26 ? 748 TYR B C 1 ATOM 11495 O O . TYR B 1 728 ? -12.097 7.609 16.288 1.00 26.47 ? 748 TYR B O 1 ATOM 11496 C CB . TYR B 1 728 ? -12.951 6.820 19.077 1.00 25.06 ? 748 TYR B CB 1 ATOM 11497 C CG . TYR B 1 728 ? -13.829 5.881 18.280 1.00 24.09 ? 748 TYR B CG 1 ATOM 11498 C CD1 . TYR B 1 728 ? -13.275 4.937 17.427 1.00 23.15 ? 748 TYR B CD1 1 ATOM 11499 C CD2 . TYR B 1 728 ? -15.219 5.989 18.328 1.00 24.48 ? 748 TYR B CD2 1 ATOM 11500 C CE1 . TYR B 1 728 ? -14.076 4.121 16.656 1.00 23.34 ? 748 TYR B CE1 1 ATOM 11501 C CE2 . TYR B 1 728 ? -16.032 5.175 17.561 1.00 23.59 ? 748 TYR B CE2 1 ATOM 11502 C CZ . TYR B 1 728 ? -15.458 4.251 16.722 1.00 23.48 ? 748 TYR B CZ 1 ATOM 11503 O OH . TYR B 1 728 ? -16.254 3.440 15.952 1.00 24.36 ? 748 TYR B OH 1 ATOM 11504 N N . ARG B 1 729 ? -11.026 9.322 17.322 1.00 27.41 ? 749 ARG B N 1 ATOM 11505 C CA . ARG B 1 729 ? -10.172 9.666 16.180 1.00 28.48 ? 749 ARG B CA 1 ATOM 11506 C C . ARG B 1 729 ? -8.726 9.941 16.604 1.00 28.62 ? 749 ARG B C 1 ATOM 11507 O O . ARG B 1 729 ? -8.463 10.203 17.777 1.00 28.39 ? 749 ARG B O 1 ATOM 11508 C CB . ARG B 1 729 ? -10.690 10.925 15.484 1.00 28.83 ? 749 ARG B CB 1 ATOM 11509 C CG . ARG B 1 729 ? -12.147 10.907 15.088 1.00 31.20 ? 749 ARG B CG 1 ATOM 11510 C CD . ARG B 1 729 ? -12.393 10.079 13.861 1.00 33.57 ? 749 ARG B CD 1 ATOM 11511 N NE . ARG B 1 729 ? -13.826 9.879 13.652 1.00 35.91 ? 749 ARG B NE 1 ATOM 11512 C CZ . ARG B 1 729 ? -14.661 10.800 13.173 1.00 38.41 ? 749 ARG B CZ 1 ATOM 11513 N NH1 . ARG B 1 729 ? -14.225 12.016 12.832 1.00 39.14 ? 749 ARG B NH1 1 ATOM 11514 N NH2 . ARG B 1 729 ? -15.950 10.503 13.030 1.00 37.96 ? 749 ARG B NH2 1 ATOM 11515 N N . PRO B 1 730 ? -7.787 9.901 15.640 1.00 28.83 ? 750 PRO B N 1 ATOM 11516 C CA . PRO B 1 730 ? -6.415 10.284 15.954 1.00 29.37 ? 750 PRO B CA 1 ATOM 11517 C C . PRO B 1 730 ? -6.302 11.750 16.365 1.00 29.96 ? 750 PRO B C 1 ATOM 11518 O O . PRO B 1 730 ? -7.146 12.567 16.006 1.00 30.11 ? 750 PRO B O 1 ATOM 11519 C CB . PRO B 1 730 ? -5.650 10.026 14.646 1.00 29.43 ? 750 PRO B CB 1 ATOM 11520 C CG . PRO B 1 730 ? -6.516 9.106 13.848 1.00 29.16 ? 750 PRO B CG 1 ATOM 11521 C CD . PRO B 1 730 ? -7.927 9.431 14.251 1.00 28.82 ? 750 PRO B CD 1 ATOM 11522 N N . VAL B 1 731 ? -5.278 12.060 17.146 1.00 30.50 ? 751 VAL B N 1 ATOM 11523 C CA . VAL B 1 731 ? -5.033 13.421 17.592 1.00 31.10 ? 751 VAL B CA 1 ATOM 11524 C C . VAL B 1 731 ? -3.589 13.772 17.274 1.00 31.49 ? 751 VAL B C 1 ATOM 11525 O O . VAL B 1 731 ? -2.649 13.148 17.782 1.00 31.04 ? 751 VAL B O 1 ATOM 11526 C CB . VAL B 1 731 ? -5.271 13.586 19.103 1.00 31.18 ? 751 VAL B CB 1 ATOM 11527 C CG1 . VAL B 1 731 ? -4.767 14.952 19.573 1.00 31.09 ? 751 VAL B CG1 1 ATOM 11528 C CG2 . VAL B 1 731 ? -6.747 13.407 19.427 1.00 30.77 ? 751 VAL B CG2 1 ATOM 11529 O OXT . VAL B 1 731 ? -3.367 14.690 16.487 1.00 32.09 ? 751 VAL B OXT 1 HETATM 11530 CU CU . CU C 2 . ? -21.169 -14.592 61.886 1.00 21.27 ? 801 CU A CU 1 HETATM 11531 CA CA . CA D 3 . ? -48.234 -19.931 45.240 1.00 20.49 ? 802 CA A CA 1 HETATM 11532 CA CA . CA E 3 . ? -47.004 -31.482 51.252 1.00 19.57 ? 803 CA A CA 1 HETATM 11533 C C1 . GOL F 4 . ? -49.177 7.024 56.657 1.00 27.00 ? 804 GOL A C1 1 HETATM 11534 O O1 . GOL F 4 . ? -49.682 5.712 56.683 1.00 27.39 ? 804 GOL A O1 1 HETATM 11535 C C2 . GOL F 4 . ? -49.441 7.649 55.297 1.00 25.86 ? 804 GOL A C2 1 HETATM 11536 O O2 . GOL F 4 . ? -48.798 6.890 54.310 1.00 25.19 ? 804 GOL A O2 1 HETATM 11537 C C3 . GOL F 4 . ? -50.933 7.768 55.025 1.00 25.41 ? 804 GOL A C3 1 HETATM 11538 O O3 . GOL F 4 . ? -51.132 8.643 53.934 1.00 25.17 ? 804 GOL A O3 1 HETATM 11539 C C1 . PNT G 5 . ? -28.307 -13.457 73.133 0.75 27.49 ? 901 PNT A C1 1 HETATM 11540 C C2 . PNT G 5 . ? -27.308 -13.603 72.184 0.75 27.23 ? 901 PNT A C2 1 HETATM 11541 C C3 . PNT G 5 . ? -27.627 -13.879 70.861 0.75 27.91 ? 901 PNT A C3 1 HETATM 11542 C C4 . PNT G 5 . ? -28.954 -14.014 70.485 0.75 28.66 ? 901 PNT A C4 1 HETATM 11543 C C5 . PNT G 5 . ? -29.957 -13.885 71.438 0.75 28.55 ? 901 PNT A C5 1 HETATM 11544 C C6 . PNT G 5 . ? -29.632 -13.610 72.757 0.75 27.89 ? 901 PNT A C6 1 HETATM 11545 C C7 . PNT G 5 . ? -28.335 -12.116 75.220 0.75 29.04 ? 901 PNT A C7 1 HETATM 11546 C C8 . PNT G 5 . ? -29.697 -12.308 75.824 0.75 29.76 ? 901 PNT A C8 1 HETATM 11547 C C9 . PNT G 5 . ? -29.322 -14.320 69.077 0.75 30.81 ? 901 PNT A C9 1 HETATM 11548 C C10 . PNT G 5 . ? -30.709 -11.432 75.100 0.75 29.55 ? 901 PNT A C10 1 HETATM 11549 C "C1'" . PNT G 5 . ? -34.120 -9.650 73.986 0.75 30.34 ? 901 PNT A "C1'" 1 HETATM 11550 C "C2'" . PNT G 5 . ? -35.162 -10.530 73.692 0.75 30.70 ? 901 PNT A "C2'" 1 HETATM 11551 C "C3'" . PNT G 5 . ? -36.279 -10.083 72.995 0.75 30.68 ? 901 PNT A "C3'" 1 HETATM 11552 C "C4'" . PNT G 5 . ? -36.369 -8.756 72.594 0.75 30.22 ? 901 PNT A "C4'" 1 HETATM 11553 C "C5'" . PNT G 5 . ? -35.333 -7.873 72.891 0.75 30.80 ? 901 PNT A "C5'" 1 HETATM 11554 C "C6'" . PNT G 5 . ? -34.210 -8.316 73.582 0.75 29.88 ? 901 PNT A "C6'" 1 HETATM 11555 C "C7'" . PNT G 5 . ? -31.920 -9.288 75.005 0.75 29.53 ? 901 PNT A "C7'" 1 HETATM 11556 C "C8'" . PNT G 5 . ? -30.900 -10.092 75.786 0.75 29.45 ? 901 PNT A "C8'" 1 HETATM 11557 C "C9'" . PNT G 5 . ? -37.580 -8.270 71.856 0.75 29.63 ? 901 PNT A "C9'" 1 HETATM 11558 O O1 . PNT G 5 . ? -27.958 -13.227 74.436 0.75 28.30 ? 901 PNT A O1 1 HETATM 11559 O "O1'" . PNT G 5 . ? -33.030 -10.124 74.672 0.75 29.20 ? 901 PNT A "O1'" 1 HETATM 11560 N N1 . PNT G 5 . ? -28.664 -13.882 68.096 0.75 31.73 ? 901 PNT A N1 1 HETATM 11561 N N2 . PNT G 5 . ? -30.368 -15.111 68.855 0.75 32.89 ? 901 PNT A N2 1 HETATM 11562 N "N1'" . PNT G 5 . ? -38.068 -8.975 70.931 0.75 30.25 ? 901 PNT A "N1'" 1 HETATM 11563 N "N2'" . PNT G 5 . ? -38.140 -7.101 72.184 0.75 28.79 ? 901 PNT A "N2'" 1 HETATM 11564 C C1 . NAG H 6 . ? -53.258 -24.273 79.500 1.00 32.68 ? 1101 NAG A C1 1 HETATM 11565 C C2 . NAG H 6 . ? -54.117 -25.523 79.376 1.00 34.84 ? 1101 NAG A C2 1 HETATM 11566 C C3 . NAG H 6 . ? -55.551 -25.094 79.103 1.00 36.22 ? 1101 NAG A C3 1 HETATM 11567 C C4 . NAG H 6 . ? -56.036 -24.143 80.187 1.00 37.07 ? 1101 NAG A C4 1 HETATM 11568 C C5 . NAG H 6 . ? -55.054 -22.971 80.285 1.00 35.21 ? 1101 NAG A C5 1 HETATM 11569 C C6 . NAG H 6 . ? -55.434 -21.955 81.355 1.00 34.89 ? 1101 NAG A C6 1 HETATM 11570 C C7 . NAG H 6 . ? -53.263 -27.607 78.381 1.00 35.85 ? 1101 NAG A C7 1 HETATM 11571 C C8 . NAG H 6 . ? -52.838 -28.289 77.114 1.00 34.51 ? 1101 NAG A C8 1 HETATM 11572 N N2 . NAG H 6 . ? -53.664 -26.336 78.264 1.00 34.69 ? 1101 NAG A N2 1 HETATM 11573 O O3 . NAG H 6 . ? -56.404 -26.213 78.983 1.00 37.17 ? 1101 NAG A O3 1 HETATM 11574 O O4 . NAG H 6 . ? -57.322 -23.691 79.819 1.00 39.60 ? 1101 NAG A O4 1 HETATM 11575 O O5 . NAG H 6 . ? -53.745 -23.458 80.542 1.00 33.22 ? 1101 NAG A O5 1 HETATM 11576 O O6 . NAG H 6 . ? -55.166 -22.502 82.624 1.00 34.53 ? 1101 NAG A O6 1 HETATM 11577 O O7 . NAG H 6 . ? -53.225 -28.228 79.442 1.00 36.11 ? 1101 NAG A O7 1 HETATM 11578 C C1 . NAG I 6 . ? -58.258 -23.764 80.908 1.00 42.90 ? 1102 NAG A C1 1 HETATM 11579 C C2 . NAG I 6 . ? -59.483 -22.964 80.523 1.00 44.07 ? 1102 NAG A C2 1 HETATM 11580 C C3 . NAG I 6 . ? -60.569 -23.000 81.597 1.00 46.13 ? 1102 NAG A C3 1 HETATM 11581 C C4 . NAG I 6 . ? -60.733 -24.339 82.307 1.00 47.03 ? 1102 NAG A C4 1 HETATM 11582 C C5 . NAG I 6 . ? -59.437 -25.151 82.385 1.00 46.90 ? 1102 NAG A C5 1 HETATM 11583 C C6 . NAG I 6 . ? -59.752 -26.622 82.621 1.00 47.65 ? 1102 NAG A C6 1 HETATM 11584 C C7 . NAG I 6 . ? -58.975 -21.021 79.130 1.00 43.22 ? 1102 NAG A C7 1 HETATM 11585 C C8 . NAG I 6 . ? -58.532 -19.588 79.107 1.00 41.30 ? 1102 NAG A C8 1 HETATM 11586 N N2 . NAG I 6 . ? -59.067 -21.588 80.326 1.00 43.92 ? 1102 NAG A N2 1 HETATM 11587 O O3 . NAG I 6 . ? -61.801 -22.628 81.023 1.00 46.72 ? 1102 NAG A O3 1 HETATM 11588 O O4 . NAG I 6 . ? -61.138 -24.029 83.623 1.00 49.14 ? 1102 NAG A O4 1 HETATM 11589 O O5 . NAG I 6 . ? -58.660 -25.072 81.206 1.00 44.28 ? 1102 NAG A O5 1 HETATM 11590 O O6 . NAG I 6 . ? -58.545 -27.288 82.904 1.00 49.06 ? 1102 NAG A O6 1 HETATM 11591 O O7 . NAG I 6 . ? -59.234 -21.617 78.088 1.00 44.18 ? 1102 NAG A O7 1 HETATM 11592 C C1 . BMA J 7 . ? -62.462 -24.373 84.121 1.00 50.33 ? 1103 BMA A C1 1 HETATM 11593 C C2 . BMA J 7 . ? -63.629 -23.951 83.225 1.00 51.10 ? 1103 BMA A C2 1 HETATM 11594 C C3 . BMA J 7 . ? -64.962 -24.361 83.837 1.00 51.34 ? 1103 BMA A C3 1 HETATM 11595 C C4 . BMA J 7 . ? -64.922 -25.798 84.332 1.00 51.09 ? 1103 BMA A C4 1 HETATM 11596 C C5 . BMA J 7 . ? -63.724 -26.018 85.240 1.00 51.69 ? 1103 BMA A C5 1 HETATM 11597 C C6 . BMA J 7 . ? -63.667 -27.460 85.752 1.00 52.10 ? 1103 BMA A C6 1 HETATM 11598 O O2 . BMA J 7 . ? -63.562 -24.496 81.935 1.00 51.77 ? 1103 BMA A O2 1 HETATM 11599 O O3 . BMA J 7 . ? -65.960 -24.245 82.852 1.00 51.92 ? 1103 BMA A O3 1 HETATM 11600 O O4 . BMA J 7 . ? -66.090 -26.077 85.046 1.00 51.39 ? 1103 BMA A O4 1 HETATM 11601 O O5 . BMA J 7 . ? -62.574 -25.735 84.466 1.00 51.50 ? 1103 BMA A O5 1 HETATM 11602 O O6 . BMA J 7 . ? -64.096 -27.555 87.092 1.00 52.29 ? 1103 BMA A O6 1 HETATM 11603 C C1 . NAG K 6 . ? -18.532 -37.633 19.317 1.00 32.54 ? 5381 NAG A C1 1 HETATM 11604 C C2 . NAG K 6 . ? -17.298 -38.009 20.134 1.00 33.68 ? 5381 NAG A C2 1 HETATM 11605 C C3 . NAG K 6 . ? -16.202 -38.548 19.217 1.00 35.87 ? 5381 NAG A C3 1 HETATM 11606 C C4 . NAG K 6 . ? -16.718 -39.699 18.356 1.00 37.59 ? 5381 NAG A C4 1 HETATM 11607 C C5 . NAG K 6 . ? -17.989 -39.239 17.646 1.00 36.21 ? 5381 NAG A C5 1 HETATM 11608 C C6 . NAG K 6 . ? -18.629 -40.341 16.803 1.00 36.44 ? 5381 NAG A C6 1 HETATM 11609 C C7 . NAG K 6 . ? -17.184 -36.537 22.075 1.00 31.68 ? 5381 NAG A C7 1 HETATM 11610 C C8 . NAG K 6 . ? -16.505 -35.359 22.719 1.00 30.18 ? 5381 NAG A C8 1 HETATM 11611 N N2 . NAG K 6 . ? -16.755 -36.886 20.874 1.00 32.58 ? 5381 NAG A N2 1 HETATM 11612 O O3 . NAG K 6 . ? -15.086 -38.929 19.985 1.00 35.37 ? 5381 NAG A O3 1 HETATM 11613 O O4 . NAG K 6 . ? -15.766 -39.973 17.358 1.00 41.19 ? 5381 NAG A O4 1 HETATM 11614 O O5 . NAG K 6 . ? -18.937 -38.782 18.584 1.00 33.31 ? 5381 NAG A O5 1 HETATM 11615 O O6 . NAG K 6 . ? -18.912 -41.441 17.629 1.00 36.53 ? 5381 NAG A O6 1 HETATM 11616 O O7 . NAG K 6 . ? -18.095 -37.132 22.637 1.00 31.95 ? 5381 NAG A O7 1 HETATM 11617 C C1 . NAG L 6 . ? -15.153 -41.270 17.461 1.00 45.40 ? 5382 NAG A C1 1 HETATM 11618 C C2 . NAG L 6 . ? -14.575 -41.574 16.082 1.00 46.62 ? 5382 NAG A C2 1 HETATM 11619 C C3 . NAG L 6 . ? -13.732 -42.839 16.061 1.00 47.88 ? 5382 NAG A C3 1 HETATM 11620 C C4 . NAG L 6 . ? -12.743 -42.868 17.211 1.00 48.47 ? 5382 NAG A C4 1 HETATM 11621 C C5 . NAG L 6 . ? -13.364 -42.464 18.550 1.00 48.61 ? 5382 NAG A C5 1 HETATM 11622 C C6 . NAG L 6 . ? -12.244 -42.201 19.552 1.00 48.97 ? 5382 NAG A C6 1 HETATM 11623 C C7 . NAG L 6 . ? -15.981 -40.766 14.242 1.00 47.99 ? 5382 NAG A C7 1 HETATM 11624 C C8 . NAG L 6 . ? -17.123 -41.092 13.325 1.00 48.08 ? 5382 NAG A C8 1 HETATM 11625 N N2 . NAG L 6 . ? -15.653 -41.718 15.118 1.00 47.33 ? 5382 NAG A N2 1 HETATM 11626 O O3 . NAG L 6 . ? -13.013 -42.925 14.846 1.00 48.31 ? 5382 NAG A O3 1 HETATM 11627 O O4 . NAG L 6 . ? -12.248 -44.187 17.282 1.00 49.75 ? 5382 NAG A O4 1 HETATM 11628 O O5 . NAG L 6 . ? -14.150 -41.282 18.457 1.00 47.08 ? 5382 NAG A O5 1 HETATM 11629 O O6 . NAG L 6 . ? -12.761 -42.230 20.865 1.00 50.17 ? 5382 NAG A O6 1 HETATM 11630 O O7 . NAG L 6 . ? -15.416 -39.671 14.168 1.00 48.22 ? 5382 NAG A O7 1 HETATM 11631 C C1 . NAG M 6 . ? -36.950 11.112 71.913 1.00 35.12 ? 7451 NAG A C1 1 HETATM 11632 C C2 . NAG M 6 . ? -36.383 12.304 72.668 1.00 37.61 ? 7451 NAG A C2 1 HETATM 11633 C C3 . NAG M 6 . ? -37.328 12.810 73.745 1.00 39.27 ? 7451 NAG A C3 1 HETATM 11634 C C4 . NAG M 6 . ? -38.762 12.863 73.246 1.00 41.57 ? 7451 NAG A C4 1 HETATM 11635 C C5 . NAG M 6 . ? -39.181 11.550 72.603 1.00 40.15 ? 7451 NAG A C5 1 HETATM 11636 C C6 . NAG M 6 . ? -40.580 11.654 72.014 1.00 40.48 ? 7451 NAG A C6 1 HETATM 11637 C C7 . NAG M 6 . ? -33.921 12.230 72.772 1.00 38.17 ? 7451 NAG A C7 1 HETATM 11638 C C8 . NAG M 6 . ? -32.752 11.717 73.560 1.00 38.62 ? 7451 NAG A C8 1 HETATM 11639 N N2 . NAG M 6 . ? -35.118 11.920 73.270 1.00 38.06 ? 7451 NAG A N2 1 HETATM 11640 O O3 . NAG M 6 . ? -36.901 14.105 74.074 1.00 38.88 ? 7451 NAG A O3 1 HETATM 11641 O O4 . NAG M 6 . ? -39.649 13.135 74.308 1.00 46.50 ? 7451 NAG A O4 1 HETATM 11642 O O5 . NAG M 6 . ? -38.300 11.285 71.549 1.00 37.20 ? 7451 NAG A O5 1 HETATM 11643 O O6 . NAG M 6 . ? -40.635 12.755 71.134 1.00 40.50 ? 7451 NAG A O6 1 HETATM 11644 O O7 . NAG M 6 . ? -33.738 12.888 71.748 1.00 37.78 ? 7451 NAG A O7 1 HETATM 11645 C C1 . NAG N 6 . ? -40.073 14.506 74.219 1.00 51.14 ? 7452 NAG A C1 1 HETATM 11646 C C2 . NAG N 6 . ? -41.273 14.723 75.120 1.00 52.78 ? 7452 NAG A C2 1 HETATM 11647 C C3 . NAG N 6 . ? -41.713 16.186 75.091 1.00 54.18 ? 7452 NAG A C3 1 HETATM 11648 C C4 . NAG N 6 . ? -40.545 17.178 75.176 1.00 54.74 ? 7452 NAG A C4 1 HETATM 11649 C C5 . NAG N 6 . ? -39.322 16.742 74.369 1.00 54.69 ? 7452 NAG A C5 1 HETATM 11650 C C6 . NAG N 6 . ? -38.099 17.587 74.734 1.00 55.05 ? 7452 NAG A C6 1 HETATM 11651 C C7 . NAG N 6 . ? -42.619 12.679 75.255 1.00 53.66 ? 7452 NAG A C7 1 HETATM 11652 C C8 . NAG N 6 . ? -43.785 11.921 74.692 1.00 53.61 ? 7452 NAG A C8 1 HETATM 11653 N N2 . NAG N 6 . ? -42.366 13.862 74.694 1.00 53.07 ? 7452 NAG A N2 1 HETATM 11654 O O3 . NAG N 6 . ? -42.603 16.393 76.169 1.00 54.97 ? 7452 NAG A O3 1 HETATM 11655 O O4 . NAG N 6 . ? -40.943 18.445 74.684 1.00 55.36 ? 7452 NAG A O4 1 HETATM 11656 O O5 . NAG N 6 . ? -39.037 15.381 74.605 1.00 53.26 ? 7452 NAG A O5 1 HETATM 11657 O O6 . NAG N 6 . ? -37.463 18.038 73.557 1.00 55.25 ? 7452 NAG A O6 1 HETATM 11658 O O7 . NAG N 6 . ? -41.958 12.204 76.182 1.00 54.08 ? 7452 NAG A O7 1 HETATM 11659 CU CU . CU O 2 . ? -25.617 -13.900 27.324 1.00 19.57 ? 801 CU B CU 1 HETATM 11660 CA CA . CA P 3 . ? 1.999 -13.877 43.782 1.00 24.30 ? 802 CA B CA 1 HETATM 11661 CA CA . CA Q 3 . ? 3.726 -24.951 36.776 1.00 37.10 ? 803 CA B CA 1 HETATM 11662 C C1 . PNT R 5 . ? -19.253 -10.005 15.981 0.75 25.00 ? 901 PNT B C1 1 HETATM 11663 C C2 . PNT R 5 . ? -20.172 -10.523 16.880 0.75 24.56 ? 901 PNT B C2 1 HETATM 11664 C C3 . PNT R 5 . ? -19.802 -10.906 18.144 0.75 24.08 ? 901 PNT B C3 1 HETATM 11665 C C4 . PNT R 5 . ? -18.484 -10.781 18.522 0.75 25.04 ? 901 PNT B C4 1 HETATM 11666 C C5 . PNT R 5 . ? -17.538 -10.274 17.636 0.75 25.36 ? 901 PNT B C5 1 HETATM 11667 C C6 . PNT R 5 . ? -17.922 -9.892 16.364 0.75 24.38 ? 901 PNT B C6 1 HETATM 11668 C C7 . PNT R 5 . ? -19.408 -8.815 13.685 0.75 27.59 ? 901 PNT B C7 1 HETATM 11669 C C8 . PNT R 5 . ? -17.954 -8.460 13.559 0.75 28.14 ? 901 PNT B C8 1 HETATM 11670 C C9 . PNT R 5 . ? -18.080 -11.214 19.877 0.75 25.12 ? 901 PNT B C9 1 HETATM 11671 C C10 . PNT R 5 . ? -17.532 -7.343 14.507 0.75 28.73 ? 901 PNT B C10 1 HETATM 11672 C "C1'" . PNT R 5 . ? -14.244 -5.128 15.683 0.75 29.00 ? 901 PNT B "C1'" 1 HETATM 11673 C "C2'" . PNT R 5 . ? -13.053 -5.816 15.956 0.75 28.45 ? 901 PNT B "C2'" 1 HETATM 11674 C "C3'" . PNT R 5 . ? -12.069 -5.236 16.762 0.75 28.60 ? 901 PNT B "C3'" 1 HETATM 11675 C "C4'" . PNT R 5 . ? -12.262 -3.963 17.291 0.75 27.94 ? 901 PNT B "C4'" 1 HETATM 11676 C "C5'" . PNT R 5 . ? -13.439 -3.277 17.013 0.75 28.51 ? 901 PNT B "C5'" 1 HETATM 11677 C "C6'" . PNT R 5 . ? -14.426 -3.847 16.217 0.75 28.50 ? 901 PNT B "C6'" 1 HETATM 11678 C "C7'" . PNT R 5 . ? -16.465 -5.090 14.628 0.75 28.89 ? 901 PNT B "C7'" 1 HETATM 11679 C "C8'" . PNT R 5 . ? -17.342 -6.010 13.794 0.75 28.80 ? 901 PNT B "C8'" 1 HETATM 11680 C "C9'" . PNT R 5 . ? -11.225 -3.306 18.161 0.75 27.93 ? 901 PNT B "C9'" 1 HETATM 11681 O O1 . PNT R 5 . ? -19.793 -9.680 14.760 0.75 26.50 ? 901 PNT B O1 1 HETATM 11682 O "O1'" . PNT R 5 . ? -15.209 -5.716 14.898 0.75 27.62 ? 901 PNT B "O1'" 1 HETATM 11683 N N1 . PNT R 5 . ? -18.851 -11.103 20.863 0.75 25.42 ? 901 PNT B N1 1 HETATM 11684 N N2 . PNT R 5 . ? -16.879 -11.754 20.034 0.75 27.90 ? 901 PNT B N2 1 HETATM 11685 N "N1'" . PNT R 5 . ? -10.724 -3.960 19.115 0.75 28.69 ? 901 PNT B "N1'" 1 HETATM 11686 N "N2'" . PNT R 5 . ? -10.854 -2.040 17.956 0.75 25.25 ? 901 PNT B "N2'" 1 HETATM 11687 C C1 . NAG S 6 . ? 7.579 -14.549 9.394 1.00 31.43 ? 1101 NAG B C1 1 HETATM 11688 C C2 . NAG S 6 . ? 8.735 -15.526 9.575 1.00 33.61 ? 1101 NAG B C2 1 HETATM 11689 C C3 . NAG S 6 . ? 10.089 -14.825 9.715 1.00 34.42 ? 1101 NAG B C3 1 HETATM 11690 C C4 . NAG S 6 . ? 10.225 -13.537 8.901 1.00 34.30 ? 1101 NAG B C4 1 HETATM 11691 C C5 . NAG S 6 . ? 8.937 -12.731 8.851 1.00 33.84 ? 1101 NAG B C5 1 HETATM 11692 C C6 . NAG S 6 . ? 9.096 -11.537 7.909 1.00 34.03 ? 1101 NAG B C6 1 HETATM 11693 C C7 . NAG S 6 . ? 8.387 -17.592 10.799 1.00 36.31 ? 1101 NAG B C7 1 HETATM 11694 C C8 . NAG S 6 . ? 8.168 -18.309 12.096 1.00 36.33 ? 1101 NAG B C8 1 HETATM 11695 N N2 . NAG S 6 . ? 8.520 -16.282 10.806 1.00 34.81 ? 1101 NAG B N2 1 HETATM 11696 O O3 . NAG S 6 . ? 11.109 -15.755 9.398 1.00 32.65 ? 1101 NAG B O3 1 HETATM 11697 O O4 . NAG S 6 . ? 11.164 -12.700 9.534 1.00 36.42 ? 1101 NAG B O4 1 HETATM 11698 O O5 . NAG S 6 . ? 7.879 -13.562 8.434 1.00 33.12 ? 1101 NAG B O5 1 HETATM 11699 O O6 . NAG S 6 . ? 9.164 -11.964 6.566 1.00 32.74 ? 1101 NAG B O6 1 HETATM 11700 O O7 . NAG S 6 . ? 8.432 -18.215 9.753 1.00 39.23 ? 1101 NAG B O7 1 HETATM 11701 C C1 . NAG T 6 . ? 12.360 -12.553 8.754 1.00 39.38 ? 1102 NAG B C1 1 HETATM 11702 C C2 . NAG T 6 . ? 13.166 -11.403 9.340 1.00 39.65 ? 1102 NAG B C2 1 HETATM 11703 C C3 . NAG T 6 . ? 14.533 -11.260 8.679 1.00 41.45 ? 1102 NAG B C3 1 HETATM 11704 C C4 . NAG T 6 . ? 15.235 -12.601 8.519 1.00 42.37 ? 1102 NAG B C4 1 HETATM 11705 C C5 . NAG T 6 . ? 14.277 -13.642 7.937 1.00 43.05 ? 1102 NAG B C5 1 HETATM 11706 C C6 . NAG T 6 . ? 14.928 -15.018 7.785 1.00 43.75 ? 1102 NAG B C6 1 HETATM 11707 C C7 . NAG T 6 . ? 11.962 -9.522 10.304 1.00 38.98 ? 1102 NAG B C7 1 HETATM 11708 C C8 . NAG T 6 . ? 11.216 -8.244 10.065 1.00 38.67 ? 1102 NAG B C8 1 HETATM 11709 N N2 . NAG T 6 . ? 12.430 -10.155 9.234 1.00 38.58 ? 1102 NAG B N2 1 HETATM 11710 O O3 . NAG T 6 . ? 15.330 -10.397 9.463 1.00 42.01 ? 1102 NAG B O3 1 HETATM 11711 O O4 . NAG T 6 . ? 16.325 -12.408 7.644 1.00 44.06 ? 1102 NAG B O4 1 HETATM 11712 O O5 . NAG T 6 . ? 13.136 -13.737 8.769 1.00 40.89 ? 1102 NAG B O5 1 HETATM 11713 O O6 . NAG T 6 . ? 14.783 -15.778 8.967 1.00 45.63 ? 1102 NAG B O6 1 HETATM 11714 O O7 . NAG T 6 . ? 12.104 -9.942 11.454 1.00 39.73 ? 1102 NAG B O7 1 HETATM 11715 C C1 . NAG U 6 . ? -22.617 -39.830 68.022 1.00 31.93 ? 5381 NAG B C1 1 HETATM 11716 C C2 . NAG U 6 . ? -23.692 -40.420 67.119 1.00 32.98 ? 5381 NAG B C2 1 HETATM 11717 C C3 . NAG U 6 . ? -24.629 -41.323 67.911 1.00 34.46 ? 5381 NAG B C3 1 HETATM 11718 C C4 . NAG U 6 . ? -23.865 -42.373 68.708 1.00 35.64 ? 5381 NAG B C4 1 HETATM 11719 C C5 . NAG U 6 . ? -22.783 -41.684 69.529 1.00 35.08 ? 5381 NAG B C5 1 HETATM 11720 C C6 . NAG U 6 . ? -21.901 -42.699 70.254 1.00 34.93 ? 5381 NAG B C6 1 HETATM 11721 C C7 . NAG U 6 . ? -24.169 -38.905 65.255 1.00 31.34 ? 5381 NAG B C7 1 HETATM 11722 C C8 . NAG U 6 . ? -25.077 -37.854 64.670 1.00 30.08 ? 5381 NAG B C8 1 HETATM 11723 N N2 . NAG U 6 . ? -24.479 -39.392 66.451 1.00 32.00 ? 5381 NAG B N2 1 HETATM 11724 O O3 . NAG U 6 . ? -25.508 -41.943 67.009 1.00 33.01 ? 5381 NAG B O3 1 HETATM 11725 O O4 . NAG U 6 . ? -24.764 -42.962 69.628 1.00 39.31 ? 5381 NAG B O4 1 HETATM 11726 O O5 . NAG U 6 . ? -21.967 -40.886 68.706 1.00 32.25 ? 5381 NAG B O5 1 HETATM 11727 O O6 . NAG U 6 . ? -21.209 -43.452 69.288 1.00 35.72 ? 5381 NAG B O6 1 HETATM 11728 O O7 . NAG U 6 . ? -23.181 -39.269 64.636 1.00 30.56 ? 5381 NAG B O7 1 HETATM 11729 C C1 . NAG V 6 . ? -24.860 -44.393 69.561 1.00 42.24 ? 5382 NAG B C1 1 HETATM 11730 C C2 . NAG V 6 . ? -25.346 -44.909 70.921 1.00 44.00 ? 5382 NAG B C2 1 HETATM 11731 C C3 . NAG V 6 . ? -25.788 -46.369 70.877 1.00 45.04 ? 5382 NAG B C3 1 HETATM 11732 C C4 . NAG V 6 . ? -26.752 -46.580 69.723 1.00 45.23 ? 5382 NAG B C4 1 HETATM 11733 C C5 . NAG V 6 . ? -26.071 -46.117 68.441 1.00 45.01 ? 5382 NAG B C5 1 HETATM 11734 C C6 . NAG V 6 . ? -26.992 -46.288 67.241 1.00 44.85 ? 5382 NAG B C6 1 HETATM 11735 C C7 . NAG V 6 . ? -24.303 -43.755 72.825 1.00 45.55 ? 5382 NAG B C7 1 HETATM 11736 C C8 . NAG V 6 . ? -23.151 -43.746 73.791 1.00 46.34 ? 5382 NAG B C8 1 HETATM 11737 N N2 . NAG V 6 . ? -24.313 -44.751 71.932 1.00 44.32 ? 5382 NAG B N2 1 HETATM 11738 O O3 . NAG V 6 . ? -26.429 -46.700 72.089 1.00 45.51 ? 5382 NAG B O3 1 HETATM 11739 O O4 . NAG V 6 . ? -27.146 -47.935 69.650 1.00 45.79 ? 5382 NAG B O4 1 HETATM 11740 O O5 . NAG V 6 . ? -25.757 -44.737 68.541 1.00 43.41 ? 5382 NAG B O5 1 HETATM 11741 O O6 . NAG V 6 . ? -28.088 -45.414 67.403 1.00 45.19 ? 5382 NAG B O6 1 HETATM 11742 O O7 . NAG V 6 . ? -25.155 -42.870 72.892 1.00 45.32 ? 5382 NAG B O7 1 HETATM 11743 C C1 . NAG W 6 . ? -16.279 15.464 19.322 1.00 34.62 ? 7451 NAG B C1 1 HETATM 11744 C C2 . NAG W 6 . ? -17.144 16.543 18.679 1.00 36.13 ? 7451 NAG B C2 1 HETATM 11745 C C3 . NAG W 6 . ? -16.378 17.366 17.649 1.00 36.97 ? 7451 NAG B C3 1 HETATM 11746 C C4 . NAG W 6 . ? -15.039 17.826 18.199 1.00 37.46 ? 7451 NAG B C4 1 HETATM 11747 C C5 . NAG W 6 . ? -14.286 16.589 18.674 1.00 38.28 ? 7451 NAG B C5 1 HETATM 11748 C C6 . NAG W 6 . ? -12.892 16.900 19.214 1.00 38.50 ? 7451 NAG B C6 1 HETATM 11749 C C7 . NAG W 6 . ? -19.517 15.941 18.500 1.00 36.15 ? 7451 NAG B C7 1 HETATM 11750 C C8 . NAG W 6 . ? -20.544 15.241 17.655 1.00 36.54 ? 7451 NAG B C8 1 HETATM 11751 N N2 . NAG W 6 . ? -18.273 15.925 18.025 1.00 35.24 ? 7451 NAG B N2 1 HETATM 11752 O O3 . NAG W 6 . ? -17.171 18.467 17.294 1.00 36.92 ? 7451 NAG B O3 1 HETATM 11753 O O4 . NAG W 6 . ? -14.311 18.473 17.173 1.00 39.35 ? 7451 NAG B O4 1 HETATM 11754 O O5 . NAG W 6 . ? -15.028 15.981 19.707 1.00 35.95 ? 7451 NAG B O5 1 HETATM 11755 O O6 . NAG W 6 . ? -13.001 17.890 20.215 1.00 41.67 ? 7451 NAG B O6 1 HETATM 11756 O O7 . NAG W 6 . ? -19.855 16.480 19.549 1.00 36.24 ? 7451 NAG B O7 1 HETATM 11757 C C1 . NAG X 6 . ? -14.070 19.874 17.420 0.50 38.76 ? 7452 NAG B C1 1 HETATM 11758 C C2 . NAG X 6 . ? -12.906 20.311 16.536 0.50 38.69 ? 7452 NAG B C2 1 HETATM 11759 C C3 . NAG X 6 . ? -12.728 21.820 16.438 0.50 38.97 ? 7452 NAG B C3 1 HETATM 11760 C C4 . NAG X 6 . ? -14.071 22.484 16.218 0.50 39.41 ? 7452 NAG B C4 1 HETATM 11761 C C5 . NAG X 6 . ? -15.006 22.026 17.321 0.50 39.35 ? 7452 NAG B C5 1 HETATM 11762 C C6 . NAG X 6 . ? -16.332 22.770 17.250 0.50 39.19 ? 7452 NAG B C6 1 HETATM 11763 C C7 . NAG X 6 . ? -11.179 18.656 16.432 0.50 37.73 ? 7452 NAG B C7 1 HETATM 11764 C C8 . NAG X 6 . ? -9.906 18.099 17.000 0.50 37.28 ? 7452 NAG B C8 1 HETATM 11765 N N2 . NAG X 6 . ? -11.681 19.722 17.028 0.50 37.80 ? 7452 NAG B N2 1 HETATM 11766 O O3 . NAG X 6 . ? -11.873 22.124 15.358 0.50 39.29 ? 7452 NAG B O3 1 HETATM 11767 O O4 . NAG X 6 . ? -13.921 23.884 16.254 0.50 40.57 ? 7452 NAG B O4 1 HETATM 11768 O O5 . NAG X 6 . ? -15.219 20.642 17.151 0.50 39.28 ? 7452 NAG B O5 1 HETATM 11769 O O6 . NAG X 6 . ? -16.672 22.973 15.898 0.50 39.12 ? 7452 NAG B O6 1 HETATM 11770 O O7 . NAG X 6 . ? -11.731 18.138 15.462 0.50 37.37 ? 7452 NAG B O7 1 HETATM 11771 O O . HOH Y 8 . ? -11.625 -10.227 75.588 1.00 20.79 ? 2 HOH A O 1 HETATM 11772 O O . HOH Y 8 . ? -48.524 -17.545 51.575 1.00 16.37 ? 6 HOH A O 1 HETATM 11773 O O . HOH Y 8 . ? -40.195 -29.953 47.567 1.00 17.38 ? 7 HOH A O 1 HETATM 11774 O O . HOH Y 8 . ? -30.714 -29.189 58.875 1.00 18.46 ? 8 HOH A O 1 HETATM 11775 O O . HOH Y 8 . ? -26.896 -26.847 32.990 1.00 26.54 ? 9 HOH A O 1 HETATM 11776 O O . HOH Y 8 . ? -30.104 13.975 68.422 1.00 45.33 ? 11 HOH A O 1 HETATM 11777 O O . HOH Y 8 . ? -37.594 -28.544 61.183 1.00 16.99 ? 12 HOH A O 1 HETATM 11778 O O . HOH Y 8 . ? -53.360 -17.023 56.329 1.00 17.85 ? 13 HOH A O 1 HETATM 11779 O O . HOH Y 8 . ? -39.907 -15.855 24.841 1.00 21.69 ? 14 HOH A O 1 HETATM 11780 O O . HOH Y 8 . ? -39.721 -9.371 22.139 1.00 16.83 ? 16 HOH A O 1 HETATM 11781 O O . HOH Y 8 . ? -44.293 6.301 60.444 1.00 28.18 ? 19 HOH A O 1 HETATM 11782 O O . HOH Y 8 . ? -48.572 -20.868 42.939 1.00 15.41 ? 20 HOH A O 1 HETATM 11783 O O . HOH Y 8 . ? -20.771 -14.893 65.912 1.00 16.67 ? 752 HOH A O 1 HETATM 11784 O O . HOH Y 8 . ? -4.751 -20.473 82.079 1.00 45.46 ? 753 HOH A O 1 HETATM 11785 O O . HOH Y 8 . ? -8.018 -25.355 78.705 1.00 48.91 ? 754 HOH A O 1 HETATM 11786 O O . HOH Y 8 . ? -42.053 -26.059 85.112 1.00 56.72 ? 755 HOH A O 1 HETATM 11787 O O . HOH Y 8 . ? -25.315 11.233 10.880 1.00 50.82 ? 756 HOH A O 1 HETATM 11788 O O . HOH Y 8 . ? -32.236 15.927 49.324 1.00 16.18 ? 757 HOH A O 1 HETATM 11789 O O . HOH Y 8 . ? -47.533 -29.182 51.570 1.00 16.07 ? 758 HOH A O 1 HETATM 11790 O O . HOH Y 8 . ? -47.149 -25.681 52.145 1.00 16.63 ? 759 HOH A O 1 HETATM 11791 O O . HOH Y 8 . ? -24.751 -18.786 44.952 1.00 46.99 ? 760 HOH A O 1 HETATM 11792 O O . HOH Y 8 . ? -27.999 -0.126 14.811 1.00 22.38 ? 761 HOH A O 1 HETATM 11793 O O . HOH Y 8 . ? -35.357 12.194 57.888 1.00 37.23 ? 762 HOH A O 1 HETATM 11794 O O . HOH Y 8 . ? -44.281 -18.163 66.328 1.00 20.72 ? 763 HOH A O 1 HETATM 11795 O O . HOH Y 8 . ? -34.054 17.211 25.482 1.00 40.83 ? 764 HOH A O 1 HETATM 11796 O O . HOH Y 8 . ? -5.793 4.996 69.578 1.00 41.36 ? 765 HOH A O 1 HETATM 11797 O O . HOH Y 8 . ? -34.948 13.922 42.841 1.00 17.56 ? 766 HOH A O 1 HETATM 11798 O O . HOH Y 8 . ? -54.595 -11.101 39.218 1.00 49.90 ? 767 HOH A O 1 HETATM 11799 O O . HOH Y 8 . ? -17.173 -8.540 66.573 1.00 14.59 ? 768 HOH A O 1 HETATM 11800 O O . HOH Y 8 . ? -64.521 -11.040 83.544 1.00 46.74 ? 769 HOH A O 1 HETATM 11801 O O . HOH Y 8 . ? -48.508 -5.488 66.320 1.00 32.95 ? 770 HOH A O 1 HETATM 11802 O O . HOH Y 8 . ? -55.217 -22.262 71.520 1.00 45.83 ? 771 HOH A O 1 HETATM 11803 O O . HOH Y 8 . ? -37.134 1.787 66.304 1.00 17.52 ? 772 HOH A O 1 HETATM 11804 O O . HOH Y 8 . ? -26.787 -11.425 48.523 1.00 36.22 ? 773 HOH A O 1 HETATM 11805 O O . HOH Y 8 . ? -22.106 -11.042 49.905 1.00 38.70 ? 774 HOH A O 1 HETATM 11806 O O . HOH Y 8 . ? -40.767 -0.647 37.167 1.00 16.19 ? 775 HOH A O 1 HETATM 11807 O O . HOH Y 8 . ? -45.234 8.234 51.924 1.00 13.95 ? 776 HOH A O 1 HETATM 11808 O O . HOH Y 8 . ? -47.512 -25.461 32.077 1.00 39.72 ? 777 HOH A O 1 HETATM 11809 O O . HOH Y 8 . ? -26.899 4.210 38.760 1.00 18.32 ? 778 HOH A O 1 HETATM 11810 O O . HOH Y 8 . ? -27.917 -22.707 77.372 1.00 22.57 ? 779 HOH A O 1 HETATM 11811 O O . HOH Y 8 . ? -35.974 7.710 48.034 1.00 18.24 ? 780 HOH A O 1 HETATM 11812 O O . HOH Y 8 . ? -34.188 -34.259 62.948 1.00 30.18 ? 781 HOH A O 1 HETATM 11813 O O . HOH Y 8 . ? -52.716 -16.581 58.948 1.00 19.83 ? 782 HOH A O 1 HETATM 11814 O O . HOH Y 8 . ? -44.466 -1.297 78.295 1.00 41.35 ? 783 HOH A O 1 HETATM 11815 O O . HOH Y 8 . ? -51.230 6.580 68.805 1.00 46.87 ? 784 HOH A O 1 HETATM 11816 O O . HOH Y 8 . ? -48.535 -39.581 49.661 1.00 14.12 ? 785 HOH A O 1 HETATM 11817 O O . HOH Y 8 . ? -66.153 -7.054 73.854 1.00 55.46 ? 786 HOH A O 1 HETATM 11818 O O . HOH Y 8 . ? -31.679 -2.539 64.895 1.00 16.67 ? 787 HOH A O 1 HETATM 11819 O O . HOH Y 8 . ? -41.611 -26.405 82.599 1.00 42.29 ? 788 HOH A O 1 HETATM 11820 O O . HOH Y 8 . ? -42.425 -22.946 27.357 1.00 32.66 ? 789 HOH A O 1 HETATM 11821 O O . HOH Y 8 . ? -26.532 9.333 50.655 1.00 18.46 ? 790 HOH A O 1 HETATM 11822 O O . HOH Y 8 . ? -44.269 -32.971 65.202 1.00 38.30 ? 791 HOH A O 1 HETATM 11823 O O . HOH Y 8 . ? -46.440 -27.508 82.926 1.00 31.62 ? 792 HOH A O 1 HETATM 11824 O O . HOH Y 8 . ? -42.414 8.325 50.977 1.00 15.52 ? 793 HOH A O 1 HETATM 11825 O O . HOH Y 8 . ? -52.053 -31.740 44.245 1.00 37.34 ? 794 HOH A O 1 HETATM 11826 O O . HOH Y 8 . ? -27.125 17.752 10.289 1.00 50.39 ? 795 HOH A O 1 HETATM 11827 O O . HOH Y 8 . ? -44.762 8.274 40.953 1.00 45.52 ? 796 HOH A O 1 HETATM 11828 O O . HOH Y 8 . ? -34.984 10.962 75.696 1.00 47.32 ? 797 HOH A O 1 HETATM 11829 O O . HOH Y 8 . ? -40.192 8.509 61.617 1.00 43.71 ? 798 HOH A O 1 HETATM 11830 O O . HOH Y 8 . ? -46.118 -12.187 27.945 1.00 26.45 ? 799 HOH A O 1 HETATM 11831 O O . HOH Y 8 . ? -5.818 -14.297 91.692 1.00 47.64 ? 800 HOH A O 1 HETATM 11832 O O . HOH Y 8 . ? -54.521 -21.801 47.119 1.00 33.85 ? 805 HOH A O 1 HETATM 11833 O O . HOH Y 8 . ? -46.552 4.537 55.485 1.00 23.63 ? 806 HOH A O 1 HETATM 11834 O O . HOH Y 8 . ? -28.271 -22.093 50.027 1.00 21.01 ? 807 HOH A O 1 HETATM 11835 O O . HOH Y 8 . ? -45.085 -23.371 25.374 1.00 42.15 ? 808 HOH A O 1 HETATM 11836 O O . HOH Y 8 . ? -40.938 -7.284 21.218 1.00 20.46 ? 809 HOH A O 1 HETATM 11837 O O . HOH Y 8 . ? -55.097 -0.891 59.093 1.00 50.37 ? 810 HOH A O 1 HETATM 11838 O O . HOH Y 8 . ? -36.619 -18.563 72.681 1.00 15.66 ? 811 HOH A O 1 HETATM 11839 O O . HOH Y 8 . ? -48.381 -3.870 39.099 1.00 16.63 ? 812 HOH A O 1 HETATM 11840 O O . HOH Y 8 . ? -34.571 -9.894 53.207 1.00 17.13 ? 813 HOH A O 1 HETATM 11841 O O . HOH Y 8 . ? -36.976 -8.733 59.070 1.00 27.76 ? 814 HOH A O 1 HETATM 11842 O O . HOH Y 8 . ? -16.286 -7.085 55.079 1.00 19.70 ? 815 HOH A O 1 HETATM 11843 O O . HOH Y 8 . ? -52.134 -5.021 48.172 1.00 20.88 ? 816 HOH A O 1 HETATM 11844 O O . HOH Y 8 . ? -47.932 -31.440 53.382 1.00 16.23 ? 817 HOH A O 1 HETATM 11845 O O . HOH Y 8 . ? -33.607 -4.089 72.443 1.00 31.47 ? 818 HOH A O 1 HETATM 11846 O O . HOH Y 8 . ? -46.619 -6.433 68.128 1.00 17.74 ? 819 HOH A O 1 HETATM 11847 O O . HOH Y 8 . ? -8.269 -7.449 67.669 1.00 23.13 ? 820 HOH A O 1 HETATM 11848 O O . HOH Y 8 . ? -42.042 -12.842 58.587 1.00 21.92 ? 821 HOH A O 1 HETATM 11849 O O . HOH Y 8 . ? -47.069 -33.869 54.714 1.00 23.40 ? 822 HOH A O 1 HETATM 11850 O O . HOH Y 8 . ? -8.545 -7.403 87.252 1.00 42.97 ? 823 HOH A O 1 HETATM 11851 O O . HOH Y 8 . ? -23.269 3.860 87.917 1.00 48.90 ? 824 HOH A O 1 HETATM 11852 O O . HOH Y 8 . ? -43.294 10.598 39.851 1.00 44.13 ? 825 HOH A O 1 HETATM 11853 O O . HOH Y 8 . ? -42.111 12.506 42.427 1.00 43.46 ? 826 HOH A O 1 HETATM 11854 O O . HOH Y 8 . ? -6.702 -13.299 64.683 1.00 18.91 ? 827 HOH A O 1 HETATM 11855 O O . HOH Y 8 . ? -28.090 13.080 31.681 1.00 45.65 ? 828 HOH A O 1 HETATM 11856 O O . HOH Y 8 . ? -29.911 9.820 33.154 1.00 51.82 ? 829 HOH A O 1 HETATM 11857 O O . HOH Y 8 . ? -53.329 4.007 66.766 1.00 25.55 ? 830 HOH A O 1 HETATM 11858 O O . HOH Y 8 . ? -40.694 6.294 71.149 1.00 38.04 ? 831 HOH A O 1 HETATM 11859 O O . HOH Y 8 . ? -42.735 -27.300 80.282 1.00 24.59 ? 832 HOH A O 1 HETATM 11860 O O . HOH Y 8 . ? -45.828 -1.368 59.942 1.00 53.10 ? 833 HOH A O 1 HETATM 11861 O O . HOH Y 8 . ? -34.958 -1.322 62.169 1.00 14.70 ? 834 HOH A O 1 HETATM 11862 O O . HOH Y 8 . ? -52.724 2.062 52.049 1.00 51.84 ? 835 HOH A O 1 HETATM 11863 O O . HOH Y 8 . ? -49.221 -25.189 35.860 1.00 31.17 ? 836 HOH A O 1 HETATM 11864 O O . HOH Y 8 . ? -38.852 -21.472 97.824 1.00 42.73 ? 837 HOH A O 1 HETATM 11865 O O . HOH Y 8 . ? -44.738 -28.771 38.691 1.00 17.41 ? 838 HOH A O 1 HETATM 11866 O O . HOH Y 8 . ? -37.265 -27.421 76.509 1.00 23.88 ? 839 HOH A O 1 HETATM 11867 O O . HOH Y 8 . ? -41.939 -3.859 20.486 1.00 28.80 ? 840 HOH A O 1 HETATM 11868 O O . HOH Y 8 . ? -26.889 18.778 28.619 1.00 34.69 ? 841 HOH A O 1 HETATM 11869 O O . HOH Y 8 . ? -53.499 -14.879 53.428 1.00 27.54 ? 842 HOH A O 1 HETATM 11870 O O . HOH Y 8 . ? -42.043 -32.079 67.004 1.00 27.55 ? 843 HOH A O 1 HETATM 11871 O O . HOH Y 8 . ? -33.110 -35.290 73.613 1.00 39.55 ? 844 HOH A O 1 HETATM 11872 O O . HOH Y 8 . ? -21.094 -3.374 52.252 1.00 19.07 ? 845 HOH A O 1 HETATM 11873 O O . HOH Y 8 . ? -34.421 -36.134 70.637 1.00 44.28 ? 846 HOH A O 1 HETATM 11874 O O . HOH Y 8 . ? -61.658 -6.960 44.158 1.00 42.05 ? 847 HOH A O 1 HETATM 11875 O O . HOH Y 8 . ? -14.744 -33.119 14.124 1.00 28.96 ? 848 HOH A O 1 HETATM 11876 O O . HOH Y 8 . ? -18.392 -15.977 66.557 1.00 20.71 ? 849 HOH A O 1 HETATM 11877 O O . HOH Y 8 . ? -15.357 -14.151 86.393 1.00 23.71 ? 850 HOH A O 1 HETATM 11878 O O . HOH Y 8 . ? -33.407 -32.137 38.717 1.00 37.96 ? 851 HOH A O 1 HETATM 11879 O O . HOH Y 8 . ? -42.909 -4.367 72.691 1.00 19.43 ? 852 HOH A O 1 HETATM 11880 O O . HOH Y 8 . ? -35.989 -24.711 51.851 1.00 17.77 ? 853 HOH A O 1 HETATM 11881 O O . HOH Y 8 . ? -28.926 -34.073 73.768 1.00 52.05 ? 854 HOH A O 1 HETATM 11882 O O . HOH Y 8 . ? -18.229 -13.131 75.510 1.00 21.71 ? 855 HOH A O 1 HETATM 11883 O O . HOH Y 8 . ? -45.546 1.184 59.302 1.00 42.26 ? 856 HOH A O 1 HETATM 11884 O O . HOH Y 8 . ? -58.532 -20.256 82.994 1.00 51.31 ? 857 HOH A O 1 HETATM 11885 O O . HOH Y 8 . ? -46.700 -23.672 60.000 1.00 17.28 ? 858 HOH A O 1 HETATM 11886 O O . HOH Y 8 . ? -19.797 -26.166 53.479 1.00 50.89 ? 859 HOH A O 1 HETATM 11887 O O . HOH Y 8 . ? -53.041 -31.375 37.702 1.00 45.26 ? 860 HOH A O 1 HETATM 11888 O O . HOH Y 8 . ? -53.397 -18.707 60.494 1.00 26.52 ? 861 HOH A O 1 HETATM 11889 O O . HOH Y 8 . ? -38.693 7.800 70.661 1.00 51.57 ? 862 HOH A O 1 HETATM 11890 O O . HOH Y 8 . ? -49.326 -13.857 24.928 1.00 41.23 ? 863 HOH A O 1 HETATM 11891 O O . HOH Y 8 . ? -49.406 4.036 58.430 1.00 32.72 ? 864 HOH A O 1 HETATM 11892 O O . HOH Y 8 . ? -49.833 1.476 57.621 1.00 54.02 ? 865 HOH A O 1 HETATM 11893 O O . HOH Y 8 . ? -50.752 -0.166 60.797 1.00 44.43 ? 866 HOH A O 1 HETATM 11894 O O . HOH Y 8 . ? -32.511 -33.888 46.895 1.00 37.55 ? 867 HOH A O 1 HETATM 11895 O O . HOH Y 8 . ? -16.026 -8.328 58.384 1.00 35.71 ? 868 HOH A O 1 HETATM 11896 O O . HOH Y 8 . ? -21.904 -23.117 95.804 1.00 40.03 ? 869 HOH A O 1 HETATM 11897 O O . HOH Y 8 . ? -24.701 3.306 54.368 1.00 21.54 ? 870 HOH A O 1 HETATM 11898 O O . HOH Y 8 . ? -7.986 0.996 70.623 1.00 38.05 ? 871 HOH A O 1 HETATM 11899 O O . HOH Y 8 . ? -21.410 -1.735 18.597 1.00 27.73 ? 872 HOH A O 1 HETATM 11900 O O . HOH Y 8 . ? -57.090 -21.548 63.691 1.00 47.75 ? 873 HOH A O 1 HETATM 11901 O O . HOH Y 8 . ? -62.440 -20.917 83.798 1.00 56.54 ? 874 HOH A O 1 HETATM 11902 O O . HOH Y 8 . ? -41.740 -20.736 21.030 1.00 16.75 ? 875 HOH A O 1 HETATM 11903 O O . HOH Y 8 . ? -35.162 10.362 29.091 1.00 21.78 ? 876 HOH A O 1 HETATM 11904 O O . HOH Y 8 . ? -10.511 -4.154 86.124 1.00 36.76 ? 877 HOH A O 1 HETATM 11905 O O . HOH Y 8 . ? -38.424 -20.668 72.383 1.00 20.56 ? 878 HOH A O 1 HETATM 11906 O O . HOH Y 8 . ? -56.633 -20.127 52.234 1.00 23.66 ? 879 HOH A O 1 HETATM 11907 O O . HOH Y 8 . ? -48.238 -23.134 52.828 1.00 16.66 ? 880 HOH A O 1 HETATM 11908 O O . HOH Y 8 . ? -30.640 -34.413 53.660 1.00 41.43 ? 881 HOH A O 1 HETATM 11909 O O . HOH Y 8 . ? -34.968 -6.476 31.523 1.00 17.49 ? 882 HOH A O 1 HETATM 11910 O O . HOH Y 8 . ? -46.851 -31.889 58.251 1.00 51.10 ? 883 HOH A O 1 HETATM 11911 O O . HOH Y 8 . ? -36.333 -35.150 39.723 1.00 40.83 ? 884 HOH A O 1 HETATM 11912 O O . HOH Y 8 . ? -27.418 -14.526 65.691 1.00 35.02 ? 885 HOH A O 1 HETATM 11913 O O . HOH Y 8 . ? -47.286 -29.044 34.877 1.00 35.18 ? 886 HOH A O 1 HETATM 11914 O O . HOH Y 8 . ? -35.185 4.554 69.264 1.00 23.54 ? 887 HOH A O 1 HETATM 11915 O O . HOH Y 8 . ? -37.724 8.922 50.226 1.00 19.44 ? 888 HOH A O 1 HETATM 11916 O O . HOH Y 8 . ? -59.687 -15.479 57.104 1.00 27.64 ? 889 HOH A O 1 HETATM 11917 O O . HOH Y 8 . ? -21.304 -24.329 61.981 1.00 33.80 ? 890 HOH A O 1 HETATM 11918 O O . HOH Y 8 . ? -34.305 -25.255 75.700 1.00 27.33 ? 891 HOH A O 1 HETATM 11919 O O . HOH Y 8 . ? -31.801 -0.517 37.666 1.00 17.31 ? 892 HOH A O 1 HETATM 11920 O O . HOH Y 8 . ? -50.226 -4.961 45.125 1.00 24.80 ? 893 HOH A O 1 HETATM 11921 O O . HOH Y 8 . ? -16.578 -21.923 73.476 1.00 23.18 ? 894 HOH A O 1 HETATM 11922 O O . HOH Y 8 . ? -54.674 -20.053 38.692 1.00 40.46 ? 895 HOH A O 1 HETATM 11923 O O . HOH Y 8 . ? -37.895 13.093 22.968 1.00 39.52 ? 896 HOH A O 1 HETATM 11924 O O . HOH Y 8 . ? -26.216 -30.071 74.109 1.00 34.84 ? 897 HOH A O 1 HETATM 11925 O O . HOH Y 8 . ? -37.082 2.662 27.632 1.00 27.61 ? 898 HOH A O 1 HETATM 11926 O O . HOH Y 8 . ? -49.087 -30.510 57.186 1.00 31.12 ? 899 HOH A O 1 HETATM 11927 O O . HOH Y 8 . ? -13.978 -15.959 96.244 1.00 27.57 ? 900 HOH A O 1 HETATM 11928 O O . HOH Y 8 . ? -50.275 3.395 65.355 1.00 24.82 ? 902 HOH A O 1 HETATM 11929 O O . HOH Y 8 . ? -26.584 -24.150 40.487 1.00 45.10 ? 903 HOH A O 1 HETATM 11930 O O . HOH Y 8 . ? -15.927 0.062 17.436 1.00 23.54 ? 904 HOH A O 1 HETATM 11931 O O . HOH Y 8 . ? -56.130 -28.286 44.548 1.00 60.88 ? 905 HOH A O 1 HETATM 11932 O O . HOH Y 8 . ? -37.279 22.036 38.749 1.00 46.98 ? 906 HOH A O 1 HETATM 11933 O O . HOH Y 8 . ? -27.860 6.607 13.569 1.00 27.60 ? 907 HOH A O 1 HETATM 11934 O O . HOH Y 8 . ? -38.704 5.406 35.321 1.00 30.26 ? 908 HOH A O 1 HETATM 11935 O O . HOH Y 8 . ? -37.309 -20.063 67.129 1.00 15.84 ? 909 HOH A O 1 HETATM 11936 O O . HOH Y 8 . ? -22.783 -27.522 76.046 1.00 21.50 ? 910 HOH A O 1 HETATM 11937 O O . HOH Y 8 . ? -55.635 -24.752 53.110 1.00 27.97 ? 911 HOH A O 1 HETATM 11938 O O . HOH Y 8 . ? -39.258 -33.887 32.340 1.00 38.72 ? 912 HOH A O 1 HETATM 11939 O O . HOH Y 8 . ? -50.969 -19.305 36.437 1.00 31.61 ? 913 HOH A O 1 HETATM 11940 O O . HOH Y 8 . ? -50.248 -15.775 59.803 1.00 28.78 ? 914 HOH A O 1 HETATM 11941 O O . HOH Y 8 . ? -38.705 -28.024 85.671 1.00 54.52 ? 915 HOH A O 1 HETATM 11942 O O . HOH Y 8 . ? -35.004 -30.243 83.675 1.00 38.37 ? 916 HOH A O 1 HETATM 11943 O O . HOH Y 8 . ? -28.859 -19.996 94.219 1.00 47.25 ? 917 HOH A O 1 HETATM 11944 O O . HOH Y 8 . ? -52.619 -26.592 65.778 1.00 39.42 ? 918 HOH A O 1 HETATM 11945 O O . HOH Y 8 . ? -32.880 -31.378 85.155 1.00 49.68 ? 919 HOH A O 1 HETATM 11946 O O . HOH Y 8 . ? -7.642 7.056 68.734 1.00 43.02 ? 920 HOH A O 1 HETATM 11947 O O . HOH Y 8 . ? -28.320 -28.041 59.433 1.00 26.03 ? 921 HOH A O 1 HETATM 11948 O O . HOH Y 8 . ? -44.277 4.944 40.668 1.00 24.84 ? 922 HOH A O 1 HETATM 11949 O O . HOH Y 8 . ? -37.046 -8.904 76.484 1.00 45.62 ? 923 HOH A O 1 HETATM 11950 O O . HOH Y 8 . ? -33.276 -30.174 32.590 1.00 25.41 ? 924 HOH A O 1 HETATM 11951 O O . HOH Y 8 . ? -32.600 -28.969 34.680 1.00 29.21 ? 925 HOH A O 1 HETATM 11952 O O . HOH Y 8 . ? -40.797 -9.738 81.461 1.00 26.93 ? 926 HOH A O 1 HETATM 11953 O O . HOH Y 8 . ? -36.691 -8.302 32.817 1.00 18.21 ? 927 HOH A O 1 HETATM 11954 O O . HOH Y 8 . ? -16.583 -16.097 80.361 1.00 22.85 ? 928 HOH A O 1 HETATM 11955 O O . HOH Y 8 . ? -27.839 -26.859 56.897 1.00 22.59 ? 929 HOH A O 1 HETATM 11956 O O . HOH Y 8 . ? -0.654 -16.687 74.389 1.00 34.54 ? 930 HOH A O 1 HETATM 11957 O O . HOH Y 8 . ? -16.450 -33.368 5.563 1.00 35.38 ? 931 HOH A O 1 HETATM 11958 O O . HOH Y 8 . ? -40.619 -3.159 73.460 1.00 28.43 ? 932 HOH A O 1 HETATM 11959 O O . HOH Y 8 . ? -42.623 -35.428 36.052 1.00 44.59 ? 933 HOH A O 1 HETATM 11960 O O . HOH Y 8 . ? -15.371 -6.384 60.170 1.00 20.29 ? 934 HOH A O 1 HETATM 11961 O O . HOH Y 8 . ? -35.176 -34.218 68.153 1.00 26.95 ? 935 HOH A O 1 HETATM 11962 O O . HOH Y 8 . ? -36.879 -4.485 71.237 1.00 19.77 ? 936 HOH A O 1 HETATM 11963 O O . HOH Y 8 . ? -11.967 -7.899 79.382 1.00 33.39 ? 937 HOH A O 1 HETATM 11964 O O . HOH Y 8 . ? -49.780 -22.378 59.430 1.00 31.58 ? 938 HOH A O 1 HETATM 11965 O O . HOH Y 8 . ? -42.566 -38.804 51.308 1.00 28.14 ? 939 HOH A O 1 HETATM 11966 O O . HOH Y 8 . ? -49.206 -6.437 64.077 1.00 21.31 ? 940 HOH A O 1 HETATM 11967 O O . HOH Y 8 . ? -40.028 -15.892 80.149 1.00 23.12 ? 941 HOH A O 1 HETATM 11968 O O . HOH Y 8 . ? -27.308 -23.004 47.656 1.00 23.51 ? 942 HOH A O 1 HETATM 11969 O O . HOH Y 8 . ? -56.228 -7.835 58.393 1.00 17.94 ? 943 HOH A O 1 HETATM 11970 O O . HOH Y 8 . ? -52.353 -22.607 71.473 1.00 28.11 ? 944 HOH A O 1 HETATM 11971 O O . HOH Y 8 . ? -43.802 -2.312 30.912 1.00 32.82 ? 945 HOH A O 1 HETATM 11972 O O . HOH Y 8 . ? -47.687 -27.835 77.323 1.00 35.02 ? 946 HOH A O 1 HETATM 11973 O O . HOH Y 8 . ? -45.083 -26.196 70.605 1.00 38.49 ? 947 HOH A O 1 HETATM 11974 O O . HOH Y 8 . ? -47.291 0.504 39.769 1.00 23.44 ? 948 HOH A O 1 HETATM 11975 O O . HOH Y 8 . ? -49.447 3.438 47.378 1.00 23.58 ? 949 HOH A O 1 HETATM 11976 O O . HOH Y 8 . ? -36.255 9.509 65.988 1.00 31.61 ? 950 HOH A O 1 HETATM 11977 O O . HOH Y 8 . ? -59.460 -1.928 64.135 1.00 31.90 ? 951 HOH A O 1 HETATM 11978 O O . HOH Y 8 . ? -43.570 -26.119 33.270 1.00 29.44 ? 952 HOH A O 1 HETATM 11979 O O . HOH Y 8 . ? -20.153 16.897 14.262 1.00 44.29 ? 953 HOH A O 1 HETATM 11980 O O . HOH Y 8 . ? -57.473 -11.105 83.639 1.00 40.39 ? 954 HOH A O 1 HETATM 11981 O O . HOH Y 8 . ? -35.327 1.999 68.448 1.00 24.03 ? 955 HOH A O 1 HETATM 11982 O O . HOH Y 8 . ? -24.098 -39.026 13.940 1.00 57.14 ? 956 HOH A O 1 HETATM 11983 O O . HOH Y 8 . ? -27.543 -26.216 78.434 1.00 24.96 ? 957 HOH A O 1 HETATM 11984 O O . HOH Y 8 . ? -14.572 -29.337 6.018 1.00 30.05 ? 958 HOH A O 1 HETATM 11985 O O . HOH Y 8 . ? -32.400 -20.103 38.457 1.00 19.53 ? 959 HOH A O 1 HETATM 11986 O O . HOH Y 8 . ? -29.049 -31.400 52.703 1.00 25.17 ? 960 HOH A O 1 HETATM 11987 O O . HOH Y 8 . ? -43.234 -29.066 35.380 1.00 35.86 ? 961 HOH A O 1 HETATM 11988 O O . HOH Y 8 . ? -27.931 -15.977 61.136 1.00 24.03 ? 962 HOH A O 1 HETATM 11989 O O . HOH Y 8 . ? -36.605 -23.314 62.627 1.00 23.30 ? 963 HOH A O 1 HETATM 11990 O O . HOH Y 8 . ? -16.978 -29.826 13.078 1.00 31.86 ? 964 HOH A O 1 HETATM 11991 O O . HOH Y 8 . ? -39.799 -1.677 75.662 1.00 28.95 ? 965 HOH A O 1 HETATM 11992 O O . HOH Y 8 . ? -57.291 -13.835 60.804 1.00 25.72 ? 966 HOH A O 1 HETATM 11993 O O . HOH Y 8 . ? -33.348 18.514 29.145 1.00 28.48 ? 967 HOH A O 1 HETATM 11994 O O . HOH Y 8 . ? -28.913 -1.004 37.721 1.00 16.30 ? 968 HOH A O 1 HETATM 11995 O O . HOH Y 8 . ? -37.522 8.192 44.379 1.00 20.56 ? 969 HOH A O 1 HETATM 11996 O O . HOH Y 8 . ? -13.072 -27.723 78.963 1.00 37.32 ? 970 HOH A O 1 HETATM 11997 O O . HOH Y 8 . ? -51.299 -31.931 69.173 1.00 46.39 ? 971 HOH A O 1 HETATM 11998 O O . HOH Y 8 . ? -20.093 -2.164 84.634 1.00 24.39 ? 972 HOH A O 1 HETATM 11999 O O . HOH Y 8 . ? -21.272 -24.445 57.223 1.00 20.83 ? 973 HOH A O 1 HETATM 12000 O O . HOH Y 8 . ? -44.390 -5.100 30.134 1.00 35.14 ? 974 HOH A O 1 HETATM 12001 O O . HOH Y 8 . ? -40.071 0.671 76.227 1.00 27.04 ? 975 HOH A O 1 HETATM 12002 O O . HOH Y 8 . ? -36.875 -35.626 60.616 1.00 37.95 ? 976 HOH A O 1 HETATM 12003 O O . HOH Y 8 . ? -30.101 17.408 21.652 1.00 34.51 ? 977 HOH A O 1 HETATM 12004 O O . HOH Y 8 . ? -54.878 -22.535 64.569 1.00 36.74 ? 978 HOH A O 1 HETATM 12005 O O . HOH Y 8 . ? -48.889 -13.895 63.567 1.00 26.25 ? 979 HOH A O 1 HETATM 12006 O O . HOH Y 8 . ? -41.744 -41.386 51.148 1.00 28.79 ? 980 HOH A O 1 HETATM 12007 O O . HOH Y 8 . ? -61.631 -21.943 70.193 1.00 48.30 ? 981 HOH A O 1 HETATM 12008 O O . HOH Y 8 . ? -26.887 -22.141 93.301 1.00 39.69 ? 982 HOH A O 1 HETATM 12009 O O . HOH Y 8 . ? -40.601 -20.204 29.455 1.00 20.44 ? 983 HOH A O 1 HETATM 12010 O O . HOH Y 8 . ? -19.944 -12.117 72.233 1.00 21.25 ? 984 HOH A O 1 HETATM 12011 O O . HOH Y 8 . ? -34.572 15.107 23.681 1.00 26.65 ? 985 HOH A O 1 HETATM 12012 O O . HOH Y 8 . ? -48.233 -12.337 57.740 1.00 35.59 ? 986 HOH A O 1 HETATM 12013 O O . HOH Y 8 . ? -62.868 -7.231 61.133 1.00 30.03 ? 987 HOH A O 1 HETATM 12014 O O . HOH Y 8 . ? -16.243 -11.283 58.581 1.00 19.78 ? 988 HOH A O 1 HETATM 12015 O O . HOH Y 8 . ? -45.253 -21.243 63.493 1.00 25.16 ? 989 HOH A O 1 HETATM 12016 O O . HOH Y 8 . ? -41.405 -19.061 60.595 1.00 28.75 ? 990 HOH A O 1 HETATM 12017 O O . HOH Y 8 . ? -11.719 -18.039 97.242 1.00 36.01 ? 991 HOH A O 1 HETATM 12018 O O . HOH Y 8 . ? -33.321 7.836 48.558 1.00 17.43 ? 992 HOH A O 1 HETATM 12019 O O . HOH Y 8 . ? -31.417 -15.639 32.068 1.00 33.84 ? 993 HOH A O 1 HETATM 12020 O O . HOH Y 8 . ? -23.742 -26.275 69.157 1.00 28.13 ? 994 HOH A O 1 HETATM 12021 O O . HOH Y 8 . ? -5.751 -20.585 93.011 1.00 45.01 ? 995 HOH A O 1 HETATM 12022 O O . HOH Y 8 . ? -27.267 -32.798 51.333 1.00 25.42 ? 996 HOH A O 1 HETATM 12023 O O . HOH Y 8 . ? -5.003 6.879 66.414 1.00 44.10 ? 997 HOH A O 1 HETATM 12024 O O . HOH Y 8 . ? -24.558 -29.110 71.988 1.00 26.84 ? 998 HOH A O 1 HETATM 12025 O O . HOH Y 8 . ? -51.530 -14.251 87.330 1.00 25.74 ? 999 HOH A O 1 HETATM 12026 O O . HOH Y 8 . ? -35.820 -34.352 73.775 1.00 32.98 ? 1000 HOH A O 1 HETATM 12027 O O . HOH Y 8 . ? -30.826 7.052 31.623 1.00 36.51 ? 1001 HOH A O 1 HETATM 12028 O O . HOH Y 8 . ? -16.828 13.755 48.422 1.00 26.92 ? 1002 HOH A O 1 HETATM 12029 O O . HOH Y 8 . ? -26.229 -33.221 70.289 1.00 36.25 ? 1003 HOH A O 1 HETATM 12030 O O . HOH Y 8 . ? -32.515 13.405 60.482 1.00 32.12 ? 1004 HOH A O 1 HETATM 12031 O O . HOH Y 8 . ? -65.478 -7.181 61.361 1.00 36.91 ? 1005 HOH A O 1 HETATM 12032 O O . HOH Y 8 . ? -47.390 -24.110 34.096 1.00 30.19 ? 1006 HOH A O 1 HETATM 12033 O O . HOH Y 8 . ? -28.756 12.607 58.114 1.00 33.04 ? 1007 HOH A O 1 HETATM 12034 O O . HOH Y 8 . ? -20.645 9.368 14.698 1.00 34.01 ? 1008 HOH A O 1 HETATM 12035 O O . HOH Y 8 . ? -62.562 -14.077 57.251 1.00 42.54 ? 1009 HOH A O 1 HETATM 12036 O O . HOH Y 8 . ? -49.312 -19.341 66.181 1.00 35.82 ? 1010 HOH A O 1 HETATM 12037 O O . HOH Y 8 . ? -38.247 9.638 68.157 1.00 38.56 ? 1011 HOH A O 1 HETATM 12038 O O . HOH Y 8 . ? -46.495 -7.213 63.657 1.00 23.17 ? 1012 HOH A O 1 HETATM 12039 O O . HOH Y 8 . ? -48.149 -3.047 57.765 1.00 29.43 ? 1013 HOH A O 1 HETATM 12040 O O . HOH Y 8 . ? -35.905 -24.112 77.958 1.00 24.72 ? 1014 HOH A O 1 HETATM 12041 O O . HOH Y 8 . ? -45.450 -16.385 18.069 1.00 38.68 ? 1015 HOH A O 1 HETATM 12042 O O . HOH Y 8 . ? -16.404 -17.891 77.757 1.00 25.88 ? 1016 HOH A O 1 HETATM 12043 O O . HOH Y 8 . ? -54.539 -19.826 85.335 1.00 39.16 ? 1017 HOH A O 1 HETATM 12044 O O . HOH Y 8 . ? -26.671 -21.633 45.519 1.00 35.49 ? 1018 HOH A O 1 HETATM 12045 O O . HOH Y 8 . ? -21.797 13.898 13.069 1.00 39.34 ? 1019 HOH A O 1 HETATM 12046 O O . HOH Y 8 . ? -30.475 18.658 28.392 1.00 37.34 ? 1020 HOH A O 1 HETATM 12047 O O . HOH Y 8 . ? -3.052 -13.988 85.054 1.00 29.36 ? 1021 HOH A O 1 HETATM 12048 O O . HOH Y 8 . ? -12.203 -10.543 78.183 1.00 35.93 ? 1022 HOH A O 1 HETATM 12049 O O . HOH Y 8 . ? -35.446 -34.111 81.142 1.00 35.89 ? 1023 HOH A O 1 HETATM 12050 O O . HOH Y 8 . ? -23.139 14.473 15.291 1.00 24.85 ? 1024 HOH A O 1 HETATM 12051 O O . HOH Y 8 . ? -52.801 -15.477 42.918 1.00 23.71 ? 1025 HOH A O 1 HETATM 12052 O O . HOH Y 8 . ? -21.906 -23.654 54.853 1.00 32.35 ? 1026 HOH A O 1 HETATM 12053 O O . HOH Y 8 . ? -50.585 -2.767 39.606 1.00 39.64 ? 1027 HOH A O 1 HETATM 12054 O O . HOH Y 8 . ? -32.839 10.231 32.251 1.00 42.65 ? 1028 HOH A O 1 HETATM 12055 O O . HOH Y 8 . ? -30.812 -34.711 81.331 1.00 33.95 ? 1029 HOH A O 1 HETATM 12056 O O . HOH Y 8 . ? -42.725 -6.082 28.267 1.00 30.16 ? 1030 HOH A O 1 HETATM 12057 O O . HOH Y 8 . ? -27.227 -27.092 71.301 1.00 28.59 ? 1031 HOH A O 1 HETATM 12058 O O . HOH Y 8 . ? -56.626 -16.940 59.733 1.00 39.58 ? 1032 HOH A O 1 HETATM 12059 O O . HOH Y 8 . ? -53.177 -25.603 47.690 1.00 35.23 ? 1033 HOH A O 1 HETATM 12060 O O . HOH Y 8 . ? -47.834 -3.140 64.936 1.00 31.46 ? 1034 HOH A O 1 HETATM 12061 O O . HOH Y 8 . ? -12.685 -30.523 84.023 1.00 39.01 ? 1035 HOH A O 1 HETATM 12062 O O . HOH Y 8 . ? -26.973 -25.720 46.655 1.00 34.00 ? 1036 HOH A O 1 HETATM 12063 O O . HOH Y 8 . ? -61.126 -3.710 73.890 1.00 31.33 ? 1037 HOH A O 1 HETATM 12064 O O . HOH Y 8 . ? -7.134 1.790 62.011 1.00 33.72 ? 1038 HOH A O 1 HETATM 12065 O O . HOH Y 8 . ? -39.324 10.046 56.395 1.00 33.41 ? 1039 HOH A O 1 HETATM 12066 O O . HOH Y 8 . ? -23.482 -6.853 52.123 1.00 27.35 ? 1040 HOH A O 1 HETATM 12067 O O . HOH Y 8 . ? -25.495 -6.307 95.322 1.00 45.24 ? 1041 HOH A O 1 HETATM 12068 O O . HOH Y 8 . ? -43.553 -7.170 20.707 1.00 39.85 ? 1042 HOH A O 1 HETATM 12069 O O . HOH Y 8 . ? -23.620 -32.266 28.905 1.00 31.30 ? 1043 HOH A O 1 HETATM 12070 O O . HOH Y 8 . ? -32.266 -37.826 67.454 1.00 43.15 ? 1044 HOH A O 1 HETATM 12071 O O . HOH Y 8 . ? -25.987 -25.096 43.915 1.00 37.72 ? 1045 HOH A O 1 HETATM 12072 O O . HOH Y 8 . ? -39.163 -22.240 27.641 1.00 51.09 ? 1046 HOH A O 1 HETATM 12073 O O . HOH Y 8 . ? -45.947 7.178 54.404 1.00 23.09 ? 1047 HOH A O 1 HETATM 12074 O O . HOH Y 8 . ? -29.926 -20.685 42.121 1.00 28.40 ? 1048 HOH A O 1 HETATM 12075 O O . HOH Y 8 . ? -8.980 -9.677 75.277 1.00 17.99 ? 1049 HOH A O 1 HETATM 12076 O O . HOH Y 8 . ? -50.042 -13.567 60.618 1.00 31.83 ? 1050 HOH A O 1 HETATM 12077 O O . HOH Y 8 . ? -35.227 -27.354 83.654 1.00 23.61 ? 1051 HOH A O 1 HETATM 12078 O O . HOH Y 8 . ? -29.498 -11.104 47.484 1.00 29.78 ? 1052 HOH A O 1 HETATM 12079 O O . HOH Y 8 . ? -35.741 -10.876 33.506 1.00 27.78 ? 1053 HOH A O 1 HETATM 12080 O O . HOH Y 8 . ? -50.997 -26.948 81.248 1.00 31.78 ? 1054 HOH A O 1 HETATM 12081 O O . HOH Y 8 . ? -35.369 -24.633 88.830 1.00 28.57 ? 1055 HOH A O 1 HETATM 12082 O O . HOH Y 8 . ? -15.029 -3.272 91.408 1.00 32.46 ? 1056 HOH A O 1 HETATM 12083 O O . HOH Y 8 . ? -38.901 -37.705 55.317 1.00 31.28 ? 1057 HOH A O 1 HETATM 12084 O O . HOH Y 8 . ? -44.205 -15.754 83.813 1.00 38.71 ? 1058 HOH A O 1 HETATM 12085 O O . HOH Y 8 . ? -16.700 1.102 79.073 1.00 28.69 ? 1059 HOH A O 1 HETATM 12086 O O . HOH Y 8 . ? -4.643 9.984 57.562 1.00 36.39 ? 1060 HOH A O 1 HETATM 12087 O O . HOH Y 8 . ? -56.300 -9.885 60.190 1.00 24.14 ? 1061 HOH A O 1 HETATM 12088 O O . HOH Y 8 . ? -59.925 -17.348 46.674 1.00 30.48 ? 1062 HOH A O 1 HETATM 12089 O O . HOH Y 8 . ? -40.430 -33.878 66.050 1.00 36.15 ? 1063 HOH A O 1 HETATM 12090 O O . HOH Y 8 . ? -64.134 -15.933 73.555 1.00 49.45 ? 1064 HOH A O 1 HETATM 12091 O O . HOH Y 8 . ? -33.275 2.135 36.240 1.00 27.57 ? 1065 HOH A O 1 HETATM 12092 O O . HOH Y 8 . ? -42.574 -26.194 71.545 1.00 32.53 ? 1066 HOH A O 1 HETATM 12093 O O . HOH Y 8 . ? -22.934 -1.470 15.643 1.00 39.24 ? 1067 HOH A O 1 HETATM 12094 O O . HOH Y 8 . ? -28.415 -28.365 46.037 1.00 41.66 ? 1068 HOH A O 1 HETATM 12095 O O . HOH Y 8 . ? -56.667 -29.681 47.454 1.00 38.63 ? 1069 HOH A O 1 HETATM 12096 O O . HOH Y 8 . ? -12.882 -14.458 86.529 1.00 28.34 ? 1070 HOH A O 1 HETATM 12097 O O . HOH Y 8 . ? -19.625 -10.214 93.368 1.00 31.67 ? 1071 HOH A O 1 HETATM 12098 O O . HOH Y 8 . ? -7.793 -21.616 64.818 1.00 24.98 ? 1072 HOH A O 1 HETATM 12099 O O . HOH Y 8 . ? -13.633 3.218 74.289 1.00 35.46 ? 1073 HOH A O 1 HETATM 12100 O O . HOH Y 8 . ? -23.240 -20.920 96.013 1.00 31.45 ? 1074 HOH A O 1 HETATM 12101 O O . HOH Y 8 . ? -37.148 17.095 47.725 1.00 30.27 ? 1075 HOH A O 1 HETATM 12102 O O . HOH Y 8 . ? -7.165 -16.034 77.916 1.00 37.90 ? 1076 HOH A O 1 HETATM 12103 O O . HOH Y 8 . ? -37.068 13.966 48.993 1.00 28.42 ? 1077 HOH A O 1 HETATM 12104 O O . HOH Y 8 . ? -42.590 -37.791 37.507 1.00 35.73 ? 1078 HOH A O 1 HETATM 12105 O O . HOH Y 8 . ? -35.795 -31.276 27.060 1.00 26.94 ? 1079 HOH A O 1 HETATM 12106 O O . HOH Y 8 . ? -27.891 -38.083 58.984 1.00 46.76 ? 1080 HOH A O 1 HETATM 12107 O O . HOH Y 8 . ? -45.767 -26.929 79.822 1.00 30.89 ? 1081 HOH A O 1 HETATM 12108 O O . HOH Y 8 . ? -50.735 -2.981 47.776 1.00 32.02 ? 1082 HOH A O 1 HETATM 12109 O O . HOH Y 8 . ? -42.324 -12.165 81.875 1.00 50.27 ? 1083 HOH A O 1 HETATM 12110 O O . HOH Y 8 . ? -34.149 21.493 50.038 1.00 30.60 ? 1084 HOH A O 1 HETATM 12111 O O . HOH Y 8 . ? -44.926 -4.051 63.808 1.00 39.70 ? 1085 HOH A O 1 HETATM 12112 O O . HOH Y 8 . ? -42.289 11.526 27.858 1.00 58.06 ? 1086 HOH A O 1 HETATM 12113 O O . HOH Y 8 . ? -36.634 -7.475 61.811 1.00 26.37 ? 1087 HOH A O 1 HETATM 12114 O O . HOH Y 8 . ? -62.417 -17.948 45.001 1.00 39.89 ? 1088 HOH A O 1 HETATM 12115 O O . HOH Y 8 . ? -39.513 -22.877 83.024 1.00 25.05 ? 1089 HOH A O 1 HETATM 12116 O O . HOH Y 8 . ? -48.536 2.699 73.384 1.00 25.60 ? 1090 HOH A O 1 HETATM 12117 O O . HOH Y 8 . ? -43.785 -11.182 79.538 1.00 46.79 ? 1091 HOH A O 1 HETATM 12118 O O . HOH Y 8 . ? -38.654 -19.760 84.369 1.00 31.86 ? 1092 HOH A O 1 HETATM 12119 O O . HOH Y 8 . ? -34.891 12.093 66.039 1.00 45.41 ? 1093 HOH A O 1 HETATM 12120 O O . HOH Y 8 . ? -51.614 -17.061 53.998 1.00 32.84 ? 1094 HOH A O 1 HETATM 12121 O O . HOH Y 8 . ? -46.719 -21.554 89.266 1.00 31.06 ? 1095 HOH A O 1 HETATM 12122 O O . HOH Y 8 . ? -57.765 1.301 71.804 1.00 30.87 ? 1096 HOH A O 1 HETATM 12123 O O . HOH Y 8 . ? -65.552 -5.224 63.166 1.00 35.71 ? 1097 HOH A O 1 HETATM 12124 O O . HOH Y 8 . ? -15.477 -13.854 98.635 1.00 32.74 ? 1098 HOH A O 1 HETATM 12125 O O . HOH Y 8 . ? -25.150 -30.527 86.234 1.00 39.79 ? 1099 HOH A O 1 HETATM 12126 O O . HOH Y 8 . ? -20.895 12.212 16.825 1.00 30.46 ? 1100 HOH A O 1 HETATM 12127 O O . HOH Y 8 . ? -33.147 7.914 37.354 1.00 42.34 ? 1104 HOH A O 1 HETATM 12128 O O . HOH Y 8 . ? -30.605 14.097 34.039 1.00 44.07 ? 1105 HOH A O 1 HETATM 12129 O O . HOH Y 8 . ? -39.281 -25.462 82.275 1.00 41.58 ? 1106 HOH A O 1 HETATM 12130 O O . HOH Y 8 . ? -8.542 10.233 57.259 1.00 48.37 ? 1107 HOH A O 1 HETATM 12131 O O . HOH Y 8 . ? -34.223 -7.547 83.539 1.00 47.58 ? 1108 HOH A O 1 HETATM 12132 O O . HOH Y 8 . ? -50.150 -9.086 80.628 1.00 37.14 ? 1109 HOH A O 1 HETATM 12133 O O . HOH Y 8 . ? -49.716 2.989 75.959 1.00 35.38 ? 1110 HOH A O 1 HETATM 12134 O O . HOH Y 8 . ? -56.116 -8.198 42.442 1.00 33.66 ? 1111 HOH A O 1 HETATM 12135 O O . HOH Y 8 . ? -22.305 -12.390 94.008 1.00 36.33 ? 1112 HOH A O 1 HETATM 12136 O O . HOH Y 8 . ? -59.804 -13.544 59.192 1.00 34.06 ? 1113 HOH A O 1 HETATM 12137 O O . HOH Y 8 . ? -28.344 -5.554 44.883 1.00 43.07 ? 1114 HOH A O 1 HETATM 12138 O O . HOH Y 8 . ? -37.677 -12.811 74.437 1.00 21.53 ? 1115 HOH A O 1 HETATM 12139 O O . HOH Y 8 . ? -22.578 -30.587 85.117 1.00 38.10 ? 1116 HOH A O 1 HETATM 12140 O O . HOH Y 8 . ? -22.932 3.719 10.035 1.00 55.90 ? 1117 HOH A O 1 HETATM 12141 O O . HOH Y 8 . ? -49.549 -0.988 46.266 1.00 33.83 ? 1118 HOH A O 1 HETATM 12142 O O . HOH Y 8 . ? -44.767 -29.871 61.142 1.00 25.20 ? 1119 HOH A O 1 HETATM 12143 O O . HOH Y 8 . ? -62.421 -4.069 76.503 1.00 41.47 ? 1120 HOH A O 1 HETATM 12144 O O . HOH Y 8 . ? -18.563 1.804 70.248 1.00 38.08 ? 1121 HOH A O 1 HETATM 12145 O O . HOH Y 8 . ? -22.372 -0.632 85.018 1.00 44.12 ? 1122 HOH A O 1 HETATM 12146 O O . HOH Y 8 . ? -8.517 -2.186 74.411 1.00 31.28 ? 1123 HOH A O 1 HETATM 12147 O O . HOH Y 8 . ? -18.834 -18.784 53.636 1.00 44.87 ? 1124 HOH A O 1 HETATM 12148 O O . HOH Y 8 . ? -40.753 -16.922 89.926 1.00 32.98 ? 1125 HOH A O 1 HETATM 12149 O O . HOH Y 8 . ? -39.550 14.600 50.088 1.00 20.67 ? 1126 HOH A O 1 HETATM 12150 O O . HOH Y 8 . ? -8.722 -19.554 62.641 1.00 37.56 ? 1127 HOH A O 1 HETATM 12151 O O . HOH Y 8 . ? -37.661 -27.320 82.998 1.00 32.90 ? 1128 HOH A O 1 HETATM 12152 O O . HOH Y 8 . ? -52.518 -11.644 37.991 1.00 30.46 ? 1129 HOH A O 1 HETATM 12153 O O . HOH Y 8 . ? -54.319 -9.024 40.615 1.00 36.17 ? 1130 HOH A O 1 HETATM 12154 O O . HOH Y 8 . ? -10.553 -14.617 84.839 1.00 27.82 ? 1131 HOH A O 1 HETATM 12155 O O . HOH Y 8 . ? -53.492 8.333 53.196 1.00 29.57 ? 1132 HOH A O 1 HETATM 12156 O O . HOH Y 8 . ? -30.145 -21.628 39.875 1.00 27.15 ? 1133 HOH A O 1 HETATM 12157 O O . HOH Y 8 . ? -36.116 -37.087 57.978 1.00 33.33 ? 1134 HOH A O 1 HETATM 12158 O O . HOH Y 8 . ? -40.993 -35.701 61.815 1.00 34.99 ? 1135 HOH A O 1 HETATM 12159 O O . HOH Y 8 . ? -36.841 20.118 46.651 1.00 40.79 ? 1136 HOH A O 1 HETATM 12160 O O . HOH Y 8 . ? -37.389 20.479 42.173 1.00 48.74 ? 1137 HOH A O 1 HETATM 12161 O O . HOH Y 8 . ? -29.268 14.511 50.686 1.00 28.33 ? 1138 HOH A O 1 HETATM 12162 O O . HOH Y 8 . ? -39.455 1.656 38.317 1.00 25.16 ? 1139 HOH A O 1 HETATM 12163 O O . HOH Y 8 . ? -38.361 3.328 36.744 1.00 41.17 ? 1140 HOH A O 1 HETATM 12164 O O . HOH Y 8 . ? -17.420 8.108 11.894 1.00 37.25 ? 1141 HOH A O 1 HETATM 12165 O O . HOH Y 8 . ? -11.660 -26.915 76.489 1.00 45.97 ? 1142 HOH A O 1 HETATM 12166 O O . HOH Y 8 . ? -58.699 -21.573 53.486 1.00 39.69 ? 1143 HOH A O 1 HETATM 12167 O O . HOH Y 8 . ? -68.615 -11.461 50.055 1.00 52.12 ? 1144 HOH A O 1 HETATM 12168 O O . HOH Y 8 . ? -54.944 -19.836 58.751 1.00 39.53 ? 1145 HOH A O 1 HETATM 12169 O O . HOH Y 8 . ? -35.533 18.362 27.617 1.00 30.53 ? 1146 HOH A O 1 HETATM 12170 O O . HOH Y 8 . ? -28.811 1.815 12.622 1.00 39.81 ? 1147 HOH A O 1 HETATM 12171 O O . HOH Y 8 . ? -45.576 -16.963 56.784 1.00 23.76 ? 1148 HOH A O 1 HETATM 12172 O O . HOH Y 8 . ? -43.050 -17.748 62.200 1.00 39.78 ? 1149 HOH A O 1 HETATM 12173 O O . HOH Y 8 . ? -38.793 -26.213 61.349 1.00 32.36 ? 1150 HOH A O 1 HETATM 12174 O O . HOH Y 8 . ? -35.056 -17.682 74.808 1.00 28.07 ? 1151 HOH A O 1 HETATM 12175 O O . HOH Y 8 . ? -54.498 -6.952 44.289 1.00 31.61 ? 1152 HOH A O 1 HETATM 12176 O O . HOH Y 8 . ? -35.417 -34.594 48.456 1.00 38.28 ? 1153 HOH A O 1 HETATM 12177 O O . HOH Y 8 . ? -43.242 -3.308 26.298 1.00 37.62 ? 1154 HOH A O 1 HETATM 12178 O O . HOH Y 8 . ? -48.787 -15.303 57.696 1.00 38.16 ? 1155 HOH A O 1 HETATM 12179 O O . HOH Y 8 . ? -28.147 -16.944 34.361 1.00 28.96 ? 1156 HOH A O 1 HETATM 12180 O O . HOH Y 8 . ? -33.430 -10.618 34.615 1.00 34.74 ? 1157 HOH A O 1 HETATM 12181 O O . HOH Y 8 . ? -20.333 -6.808 49.368 1.00 38.79 ? 1158 HOH A O 1 HETATM 12182 O O . HOH Y 8 . ? -24.958 -22.880 48.856 1.00 36.62 ? 1159 HOH A O 1 HETATM 12183 O O . HOH Y 8 . ? -29.251 -26.545 35.001 1.00 49.01 ? 1160 HOH A O 1 HETATM 12184 O O . HOH Y 8 . ? -33.659 12.057 30.574 1.00 42.90 ? 1161 HOH A O 1 HETATM 12185 O O . HOH Y 8 . ? -18.746 -37.733 11.647 1.00 39.44 ? 1162 HOH A O 1 HETATM 12186 O O . HOH Y 8 . ? -58.092 -14.832 42.751 1.00 36.87 ? 1163 HOH A O 1 HETATM 12187 O O . HOH Y 8 . ? -53.118 -26.173 85.460 1.00 41.36 ? 1164 HOH A O 1 HETATM 12188 O O . HOH Y 8 . ? -20.800 15.168 49.818 1.00 33.78 ? 1165 HOH A O 1 HETATM 12189 O O . HOH Y 8 . ? -45.609 0.452 80.065 1.00 33.92 ? 1166 HOH A O 1 HETATM 12190 O O . HOH Y 8 . ? -63.106 -12.235 51.482 1.00 47.02 ? 1167 HOH A O 1 HETATM 12191 O O . HOH Y 8 . ? -52.037 -12.109 35.181 1.00 38.83 ? 1168 HOH A O 1 HETATM 12192 O O . HOH Y 8 . ? -27.333 15.016 33.370 1.00 34.25 ? 1169 HOH A O 1 HETATM 12193 O O . HOH Y 8 . ? -24.426 -5.138 92.430 1.00 35.29 ? 1170 HOH A O 1 HETATM 12194 O O . HOH Y 8 . ? -41.529 -33.168 74.094 1.00 34.24 ? 1171 HOH A O 1 HETATM 12195 O O . HOH Y 8 . ? -38.196 8.775 18.305 1.00 45.96 ? 1172 HOH A O 1 HETATM 12196 O O . HOH Y 8 . ? -25.692 -36.597 21.232 1.00 39.43 ? 1173 HOH A O 1 HETATM 12197 O O . HOH Y 8 . ? -42.149 -16.519 81.895 1.00 23.76 ? 1174 HOH A O 1 HETATM 12198 O O . HOH Y 8 . ? -26.575 -27.021 37.765 1.00 31.52 ? 1175 HOH A O 1 HETATM 12199 O O . HOH Y 8 . ? -33.276 12.414 56.640 1.00 37.62 ? 1176 HOH A O 1 HETATM 12200 O O . HOH Y 8 . ? -25.755 -36.973 13.511 1.00 42.09 ? 1177 HOH A O 1 HETATM 12201 O O . HOH Y 8 . ? -26.166 -33.545 11.930 1.00 36.02 ? 1178 HOH A O 1 HETATM 12202 O O . HOH Y 8 . ? -35.567 3.172 35.850 1.00 34.30 ? 1179 HOH A O 1 HETATM 12203 O O . HOH Y 8 . ? -33.214 -34.610 52.859 1.00 57.11 ? 1180 HOH A O 1 HETATM 12204 O O . HOH Y 8 . ? -53.800 -24.617 89.008 1.00 37.54 ? 1181 HOH A O 1 HETATM 12205 O O . HOH Y 8 . ? -31.301 13.631 57.904 1.00 31.75 ? 1182 HOH A O 1 HETATM 12206 O O . HOH Y 8 . ? -56.583 1.654 64.555 1.00 42.18 ? 1183 HOH A O 1 HETATM 12207 O O . HOH Y 8 . ? -49.593 -4.533 81.181 1.00 27.82 ? 1184 HOH A O 1 HETATM 12208 O O . HOH Y 8 . ? -9.810 -23.540 86.415 1.00 33.65 ? 1185 HOH A O 1 HETATM 12209 O O . HOH Y 8 . ? -40.949 -20.859 85.297 1.00 32.87 ? 1186 HOH A O 1 HETATM 12210 O O . HOH Y 8 . ? -2.830 -18.240 70.441 1.00 38.39 ? 1187 HOH A O 1 HETATM 12211 O O . HOH Y 8 . ? -48.787 -14.512 90.919 1.00 43.92 ? 1188 HOH A O 1 HETATM 12212 O O . HOH Y 8 . ? -51.423 1.626 46.302 1.00 37.29 ? 1189 HOH A O 1 HETATM 12213 O O . HOH Y 8 . ? -60.343 -15.317 44.152 1.00 44.32 ? 1190 HOH A O 1 HETATM 12214 O O . HOH Y 8 . ? -17.382 -28.497 4.277 1.00 36.77 ? 1191 HOH A O 1 HETATM 12215 O O . HOH Y 8 . ? -22.862 12.028 11.392 1.00 41.36 ? 1192 HOH A O 1 HETATM 12216 O O . HOH Y 8 . ? -26.797 -9.064 44.811 1.00 49.63 ? 1193 HOH A O 1 HETATM 12217 O O . HOH Y 8 . ? -40.808 -29.285 81.340 1.00 45.00 ? 1194 HOH A O 1 HETATM 12218 O O . HOH Y 8 . ? -58.750 -7.919 57.497 1.00 37.07 ? 1195 HOH A O 1 HETATM 12219 O O . HOH Y 8 . ? -60.930 -3.670 60.444 1.00 42.22 ? 1196 HOH A O 1 HETATM 12220 O O . HOH Y 8 . ? -33.611 17.193 61.915 1.00 46.83 ? 1197 HOH A O 1 HETATM 12221 O O . HOH Y 8 . ? -17.086 -30.229 17.496 1.00 41.71 ? 1198 HOH A O 1 HETATM 12222 O O . HOH Y 8 . ? -56.116 -18.574 61.677 1.00 41.43 ? 1199 HOH A O 1 HETATM 12223 O O . HOH Y 8 . ? -31.148 16.884 26.010 1.00 39.78 ? 1200 HOH A O 1 HETATM 12224 O O . HOH Y 8 . ? -28.774 16.412 27.295 1.00 46.11 ? 1201 HOH A O 1 HETATM 12225 O O . HOH Y 8 . ? -44.810 -39.099 37.990 1.00 35.15 ? 1202 HOH A O 1 HETATM 12226 O O . HOH Y 8 . ? -42.689 -2.865 79.253 1.00 45.55 ? 1203 HOH A O 1 HETATM 12227 O O . HOH Y 8 . ? -51.441 7.018 43.454 1.00 44.51 ? 1204 HOH A O 1 HETATM 12228 O O . HOH Y 8 . ? -26.192 -31.006 67.688 1.00 38.31 ? 1205 HOH A O 1 HETATM 12229 O O . HOH Y 8 . ? -15.229 -6.956 99.392 1.00 35.03 ? 1206 HOH A O 1 HETATM 12230 O O . HOH Y 8 . ? -17.323 -6.280 100.726 1.00 38.49 ? 1207 HOH A O 1 HETATM 12231 O O . HOH Z 8 . ? -13.386 -18.433 50.322 1.00 22.26 ? 1 HOH B O 1 HETATM 12232 O O . HOH Z 8 . ? -7.656 -14.998 16.545 1.00 18.61 ? 3 HOH B O 1 HETATM 12233 O O . HOH Z 8 . ? -6.355 -23.603 26.946 1.00 17.65 ? 4 HOH B O 1 HETATM 12234 O O . HOH Z 8 . ? 4.605 -24.702 34.574 1.00 20.61 ? 5 HOH B O 1 HETATM 12235 O O . HOH Z 8 . ? -26.397 3.787 36.081 1.00 16.23 ? 10 HOH B O 1 HETATM 12236 O O . HOH Z 8 . ? -15.463 2.197 28.047 1.00 16.99 ? 15 HOH B O 1 HETATM 12237 O O . HOH Z 8 . ? -29.920 -15.075 8.785 1.00 14.94 ? 17 HOH B O 1 HETATM 12238 O O . HOH Z 8 . ? -6.941 1.899 17.569 1.00 21.17 ? 18 HOH B O 1 HETATM 12239 O O . HOH Z 8 . ? -18.696 12.055 56.797 1.00 37.43 ? 752 HOH B O 1 HETATM 12240 O O . HOH Z 8 . ? -14.884 10.692 46.447 1.00 22.80 ? 753 HOH B O 1 HETATM 12241 O O . HOH Z 8 . ? -38.854 -10.809 14.307 1.00 16.86 ? 754 HOH B O 1 HETATM 12242 O O . HOH Z 8 . ? -28.063 -15.519 22.586 1.00 21.43 ? 755 HOH B O 1 HETATM 12243 O O . HOH Z 8 . ? -13.477 14.651 38.841 1.00 31.52 ? 756 HOH B O 1 HETATM 12244 O O . HOH Z 8 . ? -37.521 -28.078 18.096 1.00 48.16 ? 757 HOH B O 1 HETATM 12245 O O . HOH Z 8 . ? -26.202 9.771 40.338 1.00 16.71 ? 758 HOH B O 1 HETATM 12246 O O . HOH Z 8 . ? -2.043 -24.359 8.413 1.00 40.11 ? 759 HOH B O 1 HETATM 12247 O O . HOH Z 8 . ? -27.927 -42.485 67.964 1.00 45.05 ? 760 HOH B O 1 HETATM 12248 O O . HOH Z 8 . ? 8.739 7.459 26.398 1.00 45.11 ? 761 HOH B O 1 HETATM 12249 O O . HOH Z 8 . ? -36.606 -8.227 10.547 1.00 22.69 ? 762 HOH B O 1 HETATM 12250 O O . HOH Z 8 . ? 1.697 -15.092 26.805 1.00 41.75 ? 763 HOH B O 1 HETATM 12251 O O . HOH Z 8 . ? -16.319 -24.506 31.463 1.00 21.31 ? 764 HOH B O 1 HETATM 12252 O O . HOH Z 8 . ? -25.937 -13.936 23.180 1.00 17.09 ? 765 HOH B O 1 HETATM 12253 O O . HOH Z 8 . ? 10.516 -27.864 44.355 1.00 40.01 ? 766 HOH B O 1 HETATM 12254 O O . HOH Z 8 . ? -28.551 -7.533 -3.795 1.00 26.10 ? 767 HOH B O 1 HETATM 12255 O O . HOH Z 8 . ? -5.467 -18.393 6.085 1.00 31.41 ? 768 HOH B O 1 HETATM 12256 O O . HOH Z 8 . ? 4.187 -15.090 29.306 1.00 33.27 ? 769 HOH B O 1 HETATM 12257 O O . HOH Z 8 . ? -35.647 -10.851 11.295 1.00 24.53 ? 770 HOH B O 1 HETATM 12258 O O . HOH Z 8 . ? 2.856 -16.600 36.026 1.00 21.30 ? 771 HOH B O 1 HETATM 12259 O O . HOH Z 8 . ? -26.232 14.808 55.183 1.00 37.49 ? 772 HOH B O 1 HETATM 12260 O O . HOH Z 8 . ? -16.595 8.547 21.464 1.00 21.87 ? 773 HOH B O 1 HETATM 12261 O O . HOH Z 8 . ? -15.609 -3.509 62.973 1.00 20.42 ? 774 HOH B O 1 HETATM 12262 O O . HOH Z 8 . ? -20.790 -29.865 29.475 1.00 53.19 ? 775 HOH B O 1 HETATM 12263 O O . HOH Z 8 . ? -18.342 0.676 25.169 1.00 15.60 ? 776 HOH B O 1 HETATM 12264 O O . HOH Z 8 . ? -2.462 -11.510 22.868 1.00 26.05 ? 777 HOH B O 1 HETATM 12265 O O . HOH Z 8 . ? 12.689 -12.707 36.039 1.00 45.41 ? 778 HOH B O 1 HETATM 12266 O O . HOH Z 8 . ? 13.565 3.105 42.855 1.00 51.61 ? 779 HOH B O 1 HETATM 12267 O O . HOH Z 8 . ? -13.569 -11.503 -3.473 1.00 47.84 ? 780 HOH B O 1 HETATM 12268 O O . HOH Z 8 . ? -17.858 -13.177 -5.071 1.00 56.66 ? 781 HOH B O 1 HETATM 12269 O O . HOH Z 8 . ? -20.166 -24.091 22.605 1.00 42.53 ? 782 HOH B O 1 HETATM 12270 O O . HOH Z 8 . ? -28.469 -21.248 15.286 1.00 15.03 ? 783 HOH B O 1 HETATM 12271 O O . HOH Z 8 . ? -16.987 -20.420 38.513 1.00 22.86 ? 784 HOH B O 1 HETATM 12272 O O . HOH Z 8 . ? -21.797 -1.584 75.396 1.00 22.63 ? 785 HOH B O 1 HETATM 12273 O O . HOH Z 8 . ? -37.716 15.501 36.605 1.00 36.21 ? 786 HOH B O 1 HETATM 12274 O O . HOH Z 8 . ? 16.506 -9.317 32.480 1.00 54.52 ? 787 HOH B O 1 HETATM 12275 O O . HOH Z 8 . ? -16.739 13.340 25.118 1.00 24.55 ? 788 HOH B O 1 HETATM 12276 O O . HOH Z 8 . ? -26.712 -4.987 39.639 1.00 39.67 ? 789 HOH B O 1 HETATM 12277 O O . HOH Z 8 . ? -18.150 -20.426 43.268 1.00 48.04 ? 790 HOH B O 1 HETATM 12278 O O . HOH Z 8 . ? -7.423 -29.039 19.798 1.00 25.64 ? 791 HOH B O 1 HETATM 12279 O O . HOH Z 8 . ? -10.757 -27.049 53.256 1.00 25.84 ? 792 HOH B O 1 HETATM 12280 O O . HOH Z 8 . ? -10.314 -28.428 55.421 1.00 31.11 ? 793 HOH B O 1 HETATM 12281 O O . HOH Z 8 . ? -13.993 -4.804 58.333 1.00 20.03 ? 794 HOH B O 1 HETATM 12282 O O . HOH Z 8 . ? -21.043 -0.574 52.405 1.00 22.96 ? 795 HOH B O 1 HETATM 12283 O O . HOH Z 8 . ? -36.170 -10.919 13.928 1.00 15.52 ? 796 HOH B O 1 HETATM 12284 O O . HOH Z 8 . ? -8.643 -18.705 25.942 1.00 16.88 ? 797 HOH B O 1 HETATM 12285 O O . HOH Z 8 . ? -27.561 -11.165 17.206 1.00 15.68 ? 798 HOH B O 1 HETATM 12286 O O . HOH Z 8 . ? -25.650 3.900 78.893 1.00 45.97 ? 799 HOH B O 1 HETATM 12287 O O . HOH Z 8 . ? -13.969 5.861 24.142 1.00 24.45 ? 800 HOH B O 1 HETATM 12288 O O . HOH Z 8 . ? -6.062 -32.353 41.909 1.00 47.85 ? 804 HOH B O 1 HETATM 12289 O O . HOH Z 8 . ? -10.030 -31.142 41.009 1.00 43.94 ? 805 HOH B O 1 HETATM 12290 O O . HOH Z 8 . ? -18.351 18.063 56.138 1.00 44.88 ? 806 HOH B O 1 HETATM 12291 O O . HOH Z 8 . ? -15.785 -33.631 81.837 1.00 43.99 ? 807 HOH B O 1 HETATM 12292 O O . HOH Z 8 . ? -33.608 -4.299 26.992 1.00 17.64 ? 808 HOH B O 1 HETATM 12293 O O . HOH Z 8 . ? -22.684 -22.878 33.500 1.00 45.55 ? 809 HOH B O 1 HETATM 12294 O O . HOH Z 8 . ? -3.414 -25.315 40.430 1.00 25.80 ? 810 HOH B O 1 HETATM 12295 O O . HOH Z 8 . ? -6.530 0.560 -0.444 1.00 40.20 ? 811 HOH B O 1 HETATM 12296 O O . HOH Z 8 . ? -24.125 -20.535 41.811 1.00 55.39 ? 812 HOH B O 1 HETATM 12297 O O . HOH Z 8 . ? -2.637 -19.606 66.548 1.00 51.50 ? 813 HOH B O 1 HETATM 12298 O O . HOH Z 8 . ? -25.405 24.126 48.919 1.00 47.94 ? 814 HOH B O 1 HETATM 12299 O O . HOH Z 8 . ? -22.419 -22.406 40.932 1.00 40.87 ? 815 HOH B O 1 HETATM 12300 O O . HOH Z 8 . ? -14.580 14.075 26.955 1.00 48.81 ? 816 HOH B O 1 HETATM 12301 O O . HOH Z 8 . ? -8.395 13.910 38.051 1.00 49.15 ? 817 HOH B O 1 HETATM 12302 O O . HOH Z 8 . ? -8.806 13.761 35.593 1.00 44.31 ? 818 HOH B O 1 HETATM 12303 O O . HOH Z 8 . ? 2.810 -8.807 29.459 1.00 32.99 ? 819 HOH B O 1 HETATM 12304 O O . HOH Z 8 . ? 6.251 -10.474 28.479 1.00 35.05 ? 820 HOH B O 1 HETATM 12305 O O . HOH Z 8 . ? -20.032 11.001 58.754 1.00 47.45 ? 821 HOH B O 1 HETATM 12306 O O . HOH Z 8 . ? -14.789 13.948 23.048 1.00 36.09 ? 822 HOH B O 1 HETATM 12307 O O . HOH Z 8 . ? -9.512 -30.163 14.002 1.00 27.09 ? 823 HOH B O 1 HETATM 12308 O O . HOH Z 8 . ? -24.354 4.133 51.716 1.00 16.39 ? 824 HOH B O 1 HETATM 12309 O O . HOH Z 8 . ? -13.801 -28.961 35.149 1.00 26.40 ? 825 HOH B O 1 HETATM 12310 O O . HOH Z 8 . ? -15.492 -19.099 46.753 1.00 29.75 ? 826 HOH B O 1 HETATM 12311 O O . HOH Z 8 . ? -25.260 12.601 59.520 1.00 31.63 ? 827 HOH B O 1 HETATM 12312 O O . HOH Z 8 . ? 2.687 -20.322 10.921 1.00 28.17 ? 828 HOH B O 1 HETATM 12313 O O . HOH Z 8 . ? -15.494 -25.330 28.873 1.00 27.34 ? 829 HOH B O 1 HETATM 12314 O O . HOH Z 8 . ? 7.634 -31.351 40.986 1.00 41.64 ? 830 HOH B O 1 HETATM 12315 O O . HOH Z 8 . ? 1.869 -11.060 37.709 1.00 20.77 ? 831 HOH B O 1 HETATM 12316 O O . HOH Z 8 . ? -31.968 -28.114 -0.887 1.00 47.78 ? 832 HOH B O 1 HETATM 12317 O O . HOH Z 8 . ? -11.599 -4.692 30.419 1.00 29.67 ? 833 HOH B O 1 HETATM 12318 O O . HOH Z 8 . ? 3.638 -22.627 36.749 1.00 27.57 ? 834 HOH B O 1 HETATM 12319 O O . HOH Z 8 . ? -10.628 -20.197 12.619 1.00 23.94 ? 835 HOH B O 1 HETATM 12320 O O . HOH Z 8 . ? -18.750 15.923 48.291 1.00 24.52 ? 836 HOH B O 1 HETATM 12321 O O . HOH Z 8 . ? -22.978 -23.696 31.207 1.00 25.95 ? 837 HOH B O 1 HETATM 12322 O O . HOH Z 8 . ? -30.281 -29.478 3.517 1.00 29.69 ? 838 HOH B O 1 HETATM 12323 O O . HOH Z 8 . ? 6.955 0.398 31.599 1.00 24.19 ? 839 HOH B O 1 HETATM 12324 O O . HOH Z 8 . ? -32.115 -8.209 34.689 1.00 20.36 ? 840 HOH B O 1 HETATM 12325 O O . HOH Z 8 . ? 14.760 -3.815 32.800 1.00 40.25 ? 841 HOH B O 1 HETATM 12326 O O . HOH Z 8 . ? 2.477 -13.715 66.717 1.00 47.02 ? 842 HOH B O 1 HETATM 12327 O O . HOH Z 8 . ? -5.093 2.248 27.053 1.00 40.01 ? 843 HOH B O 1 HETATM 12328 O O . HOH Z 8 . ? -5.764 -7.369 30.809 1.00 27.35 ? 844 HOH B O 1 HETATM 12329 O O . HOH Z 8 . ? -41.672 -15.242 -2.438 1.00 40.13 ? 845 HOH B O 1 HETATM 12330 O O . HOH Z 8 . ? -28.242 -33.851 81.844 1.00 23.70 ? 846 HOH B O 1 HETATM 12331 O O . HOH Z 8 . ? -7.831 -4.927 68.526 1.00 28.18 ? 847 HOH B O 1 HETATM 12332 O O . HOH Z 8 . ? -42.725 -20.766 0.538 1.00 44.62 ? 848 HOH B O 1 HETATM 12333 O O . HOH Z 8 . ? 2.222 -25.406 52.325 1.00 41.89 ? 849 HOH B O 1 HETATM 12334 O O . HOH Z 8 . ? 9.802 -16.532 35.462 1.00 47.59 ? 850 HOH B O 1 HETATM 12335 O O . HOH Z 8 . ? -0.248 0.399 26.155 1.00 30.75 ? 851 HOH B O 1 HETATM 12336 O O . HOH Z 8 . ? 9.874 -12.782 40.012 1.00 45.13 ? 852 HOH B O 1 HETATM 12337 O O . HOH Z 8 . ? -11.717 11.189 19.605 0.50 13.13 ? 853 HOH B O 1 HETATM 12338 O O . HOH Z 8 . ? -8.854 -21.108 36.543 1.00 20.94 ? 854 HOH B O 1 HETATM 12339 O O . HOH Z 8 . ? -32.162 -37.236 78.474 1.00 43.35 ? 855 HOH B O 1 HETATM 12340 O O . HOH Z 8 . ? -28.527 3.423 -6.495 1.00 25.84 ? 856 HOH B O 1 HETATM 12341 O O . HOH Z 8 . ? -9.438 -21.765 4.585 1.00 22.88 ? 857 HOH B O 1 HETATM 12342 O O . HOH Z 8 . ? -28.300 3.953 78.962 1.00 54.64 ? 858 HOH B O 1 HETATM 12343 O O . HOH Z 8 . ? -7.302 -9.539 9.247 1.00 22.33 ? 859 HOH B O 1 HETATM 12344 O O . HOH Z 8 . ? -29.772 -17.084 11.204 1.00 20.96 ? 860 HOH B O 1 HETATM 12345 O O . HOH Z 8 . ? -32.991 -14.039 -7.036 1.00 21.50 ? 861 HOH B O 1 HETATM 12346 O O . HOH Z 8 . ? -8.856 -15.041 21.865 1.00 16.36 ? 862 HOH B O 1 HETATM 12347 O O . HOH Z 8 . ? -17.380 -19.112 11.221 1.00 17.93 ? 863 HOH B O 1 HETATM 12348 O O . HOH Z 8 . ? -33.207 -7.484 29.726 1.00 23.65 ? 864 HOH B O 1 HETATM 12349 O O . HOH Z 8 . ? -9.686 2.667 53.100 1.00 25.43 ? 865 HOH B O 1 HETATM 12350 O O . HOH Z 8 . ? -18.337 -17.302 -4.578 1.00 33.47 ? 866 HOH B O 1 HETATM 12351 O O . HOH Z 8 . ? -25.650 -37.457 81.947 1.00 35.18 ? 867 HOH B O 1 HETATM 12352 O O . HOH Z 8 . ? -8.180 11.972 30.769 1.00 38.45 ? 868 HOH B O 1 HETATM 12353 O O . HOH Z 8 . ? -35.330 -23.628 2.269 1.00 29.02 ? 869 HOH B O 1 HETATM 12354 O O . HOH Z 8 . ? 5.471 -8.796 30.192 1.00 23.60 ? 870 HOH B O 1 HETATM 12355 O O . HOH Z 8 . ? -42.618 -21.019 18.475 1.00 30.57 ? 871 HOH B O 1 HETATM 12356 O O . HOH Z 8 . ? -24.928 -40.602 74.703 1.00 49.44 ? 872 HOH B O 1 HETATM 12357 O O . HOH Z 8 . ? 8.369 -18.475 43.706 1.00 31.75 ? 873 HOH B O 1 HETATM 12358 O O . HOH Z 8 . ? -25.235 6.647 37.661 1.00 30.50 ? 874 HOH B O 1 HETATM 12359 O O . HOH Z 8 . ? -37.310 -25.790 0.851 1.00 41.84 ? 875 HOH B O 1 HETATM 12360 O O . HOH Z 8 . ? 2.631 -14.779 45.959 1.00 23.05 ? 876 HOH B O 1 HETATM 12361 O O . HOH Z 8 . ? 2.421 -19.203 36.566 1.00 25.84 ? 877 HOH B O 1 HETATM 12362 O O . HOH Z 8 . ? -34.376 -24.679 -13.956 1.00 62.99 ? 878 HOH B O 1 HETATM 12363 O O . HOH Z 8 . ? 8.834 -24.248 43.883 1.00 38.87 ? 879 HOH B O 1 HETATM 12364 O O . HOH Z 8 . ? 8.992 -25.740 50.269 1.00 62.34 ? 880 HOH B O 1 HETATM 12365 O O . HOH Z 8 . ? -2.150 -19.997 8.172 1.00 24.76 ? 881 HOH B O 1 HETATM 12366 O O . HOH Z 8 . ? 6.262 -4.489 50.531 1.00 53.15 ? 882 HOH B O 1 HETATM 12367 O O . HOH Z 8 . ? -11.184 -4.526 13.502 1.00 36.60 ? 883 HOH B O 1 HETATM 12368 O O . HOH Z 8 . ? -39.953 -21.244 -4.059 1.00 39.26 ? 884 HOH B O 1 HETATM 12369 O O . HOH Z 8 . ? -11.816 -6.260 56.799 1.00 19.04 ? 885 HOH B O 1 HETATM 12370 O O . HOH Z 8 . ? -18.892 -13.525 27.998 1.00 25.88 ? 886 HOH B O 1 HETATM 12371 O O . HOH Z 8 . ? -6.683 5.472 12.371 1.00 41.59 ? 887 HOH B O 1 HETATM 12372 O O . HOH Z 8 . ? -13.718 12.828 20.482 1.00 38.53 ? 888 HOH B O 1 HETATM 12373 O O . HOH Z 8 . ? -19.553 -12.276 23.157 0.70 27.20 ? 889 HOH B O 1 HETATM 12374 O O . HOH Z 8 . ? -29.159 -11.879 13.812 1.00 23.07 ? 890 HOH B O 1 HETATM 12375 O O . HOH Z 8 . ? -7.099 -33.665 23.438 1.00 51.76 ? 891 HOH B O 1 HETATM 12376 O O . HOH Z 8 . ? 4.030 -17.884 20.921 1.00 47.88 ? 892 HOH B O 1 HETATM 12377 O O . HOH Z 8 . ? -27.752 -4.514 71.242 1.00 25.79 ? 893 HOH B O 1 HETATM 12378 O O . HOH Z 8 . ? 13.221 -6.959 24.557 1.00 46.37 ? 894 HOH B O 1 HETATM 12379 O O . HOH Z 8 . ? 10.339 -11.608 36.909 1.00 37.31 ? 895 HOH B O 1 HETATM 12380 O O . HOH Z 8 . ? -18.287 0.502 52.438 1.00 19.40 ? 896 HOH B O 1 HETATM 12381 O O . HOH Z 8 . ? -7.231 -12.520 -8.974 1.00 61.91 ? 897 HOH B O 1 HETATM 12382 O O . HOH Z 8 . ? -20.720 -5.211 44.819 1.00 56.68 ? 898 HOH B O 1 HETATM 12383 O O . HOH Z 8 . ? -7.793 4.087 10.928 1.00 42.49 ? 899 HOH B O 1 HETATM 12384 O O . HOH Z 8 . ? -6.670 -0.562 63.869 1.00 51.89 ? 900 HOH B O 1 HETATM 12385 O O . HOH Z 8 . ? 10.348 -14.297 23.452 1.00 49.59 ? 902 HOH B O 1 HETATM 12386 O O . HOH Z 8 . ? 6.269 -9.256 32.954 1.00 27.14 ? 903 HOH B O 1 HETATM 12387 O O . HOH Z 8 . ? -14.316 -34.675 63.313 1.00 38.60 ? 904 HOH B O 1 HETATM 12388 O O . HOH Z 8 . ? -1.614 1.431 50.990 1.00 25.07 ? 905 HOH B O 1 HETATM 12389 O O . HOH Z 8 . ? -36.521 -14.980 4.587 1.00 16.12 ? 906 HOH B O 1 HETATM 12390 O O . HOH Z 8 . ? -7.961 -10.160 -7.416 1.00 46.40 ? 907 HOH B O 1 HETATM 12391 O O . HOH Z 8 . ? -15.729 -38.747 70.243 1.00 35.19 ? 908 HOH B O 1 HETATM 12392 O O . HOH Z 8 . ? -38.980 5.232 16.103 1.00 50.10 ? 909 HOH B O 1 HETATM 12393 O O . HOH Z 8 . ? -13.383 8.052 55.564 1.00 42.42 ? 910 HOH B O 1 HETATM 12394 O O . HOH Z 8 . ? 2.237 3.392 48.022 1.00 48.79 ? 911 HOH B O 1 HETATM 12395 O O . HOH Z 8 . ? -22.160 14.557 56.695 1.00 52.03 ? 912 HOH B O 1 HETATM 12396 O O . HOH Z 8 . ? 12.929 -9.413 23.833 1.00 54.47 ? 913 HOH B O 1 HETATM 12397 O O . HOH Z 8 . ? -13.720 -6.832 36.392 1.00 22.26 ? 914 HOH B O 1 HETATM 12398 O O . HOH Z 8 . ? 0.515 -18.795 17.592 1.00 38.10 ? 915 HOH B O 1 HETATM 12399 O O . HOH Z 8 . ? -28.241 -3.744 37.797 1.00 25.32 ? 916 HOH B O 1 HETATM 12400 O O . HOH Z 8 . ? 5.693 -8.600 46.350 1.00 31.29 ? 917 HOH B O 1 HETATM 12401 O O . HOH Z 8 . ? -26.113 -35.450 84.540 1.00 48.74 ? 918 HOH B O 1 HETATM 12402 O O . HOH Z 8 . ? -5.041 -17.043 59.405 1.00 29.18 ? 919 HOH B O 1 HETATM 12403 O O . HOH Z 8 . ? 2.353 1.637 41.865 1.00 33.29 ? 920 HOH B O 1 HETATM 12404 O O . HOH Z 8 . ? -23.657 10.655 57.635 1.00 45.43 ? 921 HOH B O 1 HETATM 12405 O O . HOH Z 8 . ? -26.320 5.907 52.390 1.00 32.14 ? 922 HOH B O 1 HETATM 12406 O O . HOH Z 8 . ? -8.907 12.888 42.319 1.00 29.45 ? 923 HOH B O 1 HETATM 12407 O O . HOH Z 8 . ? 5.888 -7.485 36.047 1.00 28.86 ? 924 HOH B O 1 HETATM 12408 O O . HOH Z 8 . ? -27.153 -36.576 73.448 1.00 30.77 ? 925 HOH B O 1 HETATM 12409 O O . HOH Z 8 . ? -22.159 17.213 42.313 1.00 22.91 ? 926 HOH B O 1 HETATM 12410 O O . HOH Z 8 . ? 13.528 -5.257 28.473 1.00 42.11 ? 927 HOH B O 1 HETATM 12411 O O . HOH Z 8 . ? 14.834 5.820 26.831 1.00 42.61 ? 928 HOH B O 1 HETATM 12412 O O . HOH Z 8 . ? -24.537 -2.643 -0.159 1.00 29.99 ? 929 HOH B O 1 HETATM 12413 O O . HOH Z 8 . ? -22.354 -6.013 6.983 1.00 31.40 ? 930 HOH B O 1 HETATM 12414 O O . HOH Z 8 . ? -32.421 4.679 13.313 1.00 44.07 ? 931 HOH B O 1 HETATM 12415 O O . HOH Z 8 . ? -41.781 -18.755 10.798 1.00 39.83 ? 932 HOH B O 1 HETATM 12416 O O . HOH Z 8 . ? -21.196 7.148 58.863 1.00 31.58 ? 933 HOH B O 1 HETATM 12417 O O . HOH Z 8 . ? 9.214 -4.855 28.801 1.00 31.06 ? 934 HOH B O 1 HETATM 12418 O O . HOH Z 8 . ? -17.756 11.314 61.865 1.00 30.82 ? 935 HOH B O 1 HETATM 12419 O O . HOH Z 8 . ? 7.634 -15.613 3.232 1.00 30.42 ? 936 HOH B O 1 HETATM 12420 O O . HOH Z 8 . ? 0.804 -19.427 8.503 1.00 34.25 ? 937 HOH B O 1 HETATM 12421 O O . HOH Z 8 . ? -6.382 -2.708 61.748 1.00 26.94 ? 938 HOH B O 1 HETATM 12422 O O . HOH Z 8 . ? -30.345 -0.364 5.653 1.00 25.35 ? 939 HOH B O 1 HETATM 12423 O O . HOH Z 8 . ? -25.696 -32.851 83.861 1.00 30.06 ? 940 HOH B O 1 HETATM 12424 O O . HOH Z 8 . ? -15.046 11.988 40.765 1.00 20.56 ? 941 HOH B O 1 HETATM 12425 O O . HOH Z 8 . ? -21.196 -24.888 12.236 1.00 28.79 ? 942 HOH B O 1 HETATM 12426 O O . HOH Z 8 . ? -12.798 -26.117 29.295 1.00 22.16 ? 943 HOH B O 1 HETATM 12427 O O . HOH Z 8 . ? -11.558 -12.579 14.221 1.00 18.87 ? 944 HOH B O 1 HETATM 12428 O O . HOH Z 8 . ? -16.789 -23.997 17.000 1.00 27.10 ? 945 HOH B O 1 HETATM 12429 O O . HOH Z 8 . ? -20.824 -27.531 2.946 1.00 30.31 ? 946 HOH B O 1 HETATM 12430 O O . HOH Z 8 . ? 1.184 -16.856 28.711 1.00 23.90 ? 947 HOH B O 1 HETATM 12431 O O . HOH Z 8 . ? 12.205 -6.867 32.354 1.00 33.08 ? 948 HOH B O 1 HETATM 12432 O O . HOH Z 8 . ? -1.429 -25.577 21.010 1.00 27.02 ? 949 HOH B O 1 HETATM 12433 O O . HOH Z 8 . ? -14.016 13.790 34.608 1.00 28.44 ? 950 HOH B O 1 HETATM 12434 O O . HOH Z 8 . ? 2.997 -14.897 16.424 1.00 46.04 ? 951 HOH B O 1 HETATM 12435 O O . HOH Z 8 . ? -48.252 -1.268 28.746 1.00 48.39 ? 952 HOH B O 1 HETATM 12436 O O . HOH Z 8 . ? -36.558 11.663 42.555 1.00 22.32 ? 953 HOH B O 1 HETATM 12437 O O . HOH Z 8 . ? -1.497 10.376 25.323 1.00 36.38 ? 954 HOH B O 1 HETATM 12438 O O . HOH Z 8 . ? -1.862 -7.963 61.697 1.00 29.52 ? 955 HOH B O 1 HETATM 12439 O O . HOH Z 8 . ? -34.121 1.545 11.733 1.00 26.09 ? 956 HOH B O 1 HETATM 12440 O O . HOH Z 8 . ? -15.142 -14.780 57.409 1.00 33.82 ? 957 HOH B O 1 HETATM 12441 O O . HOH Z 8 . ? -6.964 -28.831 13.940 1.00 24.83 ? 958 HOH B O 1 HETATM 12442 O O . HOH Z 8 . ? -34.153 -16.517 -8.257 1.00 39.05 ? 959 HOH B O 1 HETATM 12443 O O . HOH Z 8 . ? -12.962 0.307 19.002 1.00 28.65 ? 960 HOH B O 1 HETATM 12444 O O . HOH Z 8 . ? -1.698 -26.420 13.635 1.00 29.38 ? 961 HOH B O 1 HETATM 12445 O O . HOH Z 8 . ? -7.462 -28.074 6.597 1.00 36.03 ? 962 HOH B O 1 HETATM 12446 O O . HOH Z 8 . ? -7.892 -3.015 8.459 1.00 22.77 ? 963 HOH B O 1 HETATM 12447 O O . HOH Z 8 . ? -6.391 1.162 59.114 1.00 30.30 ? 964 HOH B O 1 HETATM 12448 O O . HOH Z 8 . ? -16.984 -26.305 55.207 1.00 22.13 ? 965 HOH B O 1 HETATM 12449 O O . HOH Z 8 . ? -10.599 6.460 14.210 1.00 35.89 ? 966 HOH B O 1 HETATM 12450 O O . HOH Z 8 . ? -31.566 -13.008 2.983 1.00 16.05 ? 967 HOH B O 1 HETATM 12451 O O . HOH Z 8 . ? -25.089 -6.252 37.626 1.00 27.21 ? 968 HOH B O 1 HETATM 12452 O O . HOH Z 8 . ? -19.098 -32.533 59.053 1.00 29.69 ? 969 HOH B O 1 HETATM 12453 O O . HOH Z 8 . ? -21.468 -25.503 38.595 1.00 42.15 ? 970 HOH B O 1 HETATM 12454 O O . HOH Z 8 . ? 10.665 5.870 30.043 1.00 39.44 ? 971 HOH B O 1 HETATM 12455 O O . HOH Z 8 . ? 8.509 -18.128 41.062 1.00 35.33 ? 972 HOH B O 1 HETATM 12456 O O . HOH Z 8 . ? -0.938 4.956 44.387 1.00 33.21 ? 973 HOH B O 1 HETATM 12457 O O . HOH Z 8 . ? -8.870 -24.261 4.408 1.00 45.56 ? 974 HOH B O 1 HETATM 12458 O O . HOH Z 8 . ? -5.376 -13.766 3.543 1.00 32.13 ? 975 HOH B O 1 HETATM 12459 O O . HOH Z 8 . ? -42.600 -5.911 18.209 1.00 48.15 ? 976 HOH B O 1 HETATM 12460 O O . HOH Z 8 . ? -46.466 2.513 24.043 1.00 42.80 ? 977 HOH B O 1 HETATM 12461 O O . HOH Z 8 . ? -18.448 -9.599 41.988 1.00 20.96 ? 978 HOH B O 1 HETATM 12462 O O . HOH Z 8 . ? -30.911 -8.610 23.026 1.00 21.16 ? 979 HOH B O 1 HETATM 12463 O O . HOH Z 8 . ? -18.509 -26.620 1.910 1.00 34.66 ? 980 HOH B O 1 HETATM 12464 O O . HOH Z 8 . ? -34.185 -13.841 2.839 1.00 20.69 ? 981 HOH B O 1 HETATM 12465 O O . HOH Z 8 . ? -15.838 5.941 22.089 1.00 23.04 ? 982 HOH B O 1 HETATM 12466 O O . HOH Z 8 . ? -16.000 -37.226 66.364 1.00 29.66 ? 983 HOH B O 1 HETATM 12467 O O . HOH Z 8 . ? -2.852 0.343 21.845 1.00 19.26 ? 984 HOH B O 1 HETATM 12468 O O . HOH Z 8 . ? 0.538 -26.206 12.264 1.00 29.32 ? 985 HOH B O 1 HETATM 12469 O O . HOH Z 8 . ? -43.416 -9.397 13.670 1.00 29.08 ? 986 HOH B O 1 HETATM 12470 O O . HOH Z 8 . ? -37.084 -23.554 23.822 1.00 21.22 ? 987 HOH B O 1 HETATM 12471 O O . HOH Z 8 . ? -32.131 -11.532 -9.007 1.00 40.18 ? 988 HOH B O 1 HETATM 12472 O O . HOH Z 8 . ? -31.967 1.909 20.188 1.00 28.45 ? 989 HOH B O 1 HETATM 12473 O O . HOH Z 8 . ? 13.127 3.012 28.887 1.00 35.42 ? 990 HOH B O 1 HETATM 12474 O O . HOH Z 8 . ? 16.832 -4.576 38.806 1.00 48.19 ? 991 HOH B O 1 HETATM 12475 O O . HOH Z 8 . ? -31.949 -26.895 11.835 1.00 41.42 ? 992 HOH B O 1 HETATM 12476 O O . HOH Z 8 . ? -22.273 -40.474 75.674 1.00 32.98 ? 993 HOH B O 1 HETATM 12477 O O . HOH Z 8 . ? -9.277 -30.117 48.753 1.00 48.04 ? 994 HOH B O 1 HETATM 12478 O O . HOH Z 8 . ? -2.553 -27.811 21.781 1.00 37.54 ? 995 HOH B O 1 HETATM 12479 O O . HOH Z 8 . ? 0.332 1.333 45.183 1.00 37.28 ? 996 HOH B O 1 HETATM 12480 O O . HOH Z 8 . ? -16.032 -34.860 76.045 1.00 33.20 ? 997 HOH B O 1 HETATM 12481 O O . HOH Z 8 . ? -43.760 -16.198 4.645 1.00 45.44 ? 998 HOH B O 1 HETATM 12482 O O . HOH Z 8 . ? -20.386 -24.084 19.320 1.00 28.51 ? 999 HOH B O 1 HETATM 12483 O O . HOH Z 8 . ? -24.798 13.947 33.182 1.00 23.75 ? 1000 HOH B O 1 HETATM 12484 O O . HOH Z 8 . ? -6.366 -9.392 -0.603 1.00 33.84 ? 1001 HOH B O 1 HETATM 12485 O O . HOH Z 8 . ? -31.978 -9.337 31.095 1.00 28.05 ? 1002 HOH B O 1 HETATM 12486 O O . HOH Z 8 . ? -25.794 -32.765 74.849 1.00 24.97 ? 1003 HOH B O 1 HETATM 12487 O O . HOH Z 8 . ? -7.070 -30.998 39.156 1.00 30.03 ? 1004 HOH B O 1 HETATM 12488 O O . HOH Z 8 . ? -40.898 -3.918 15.699 1.00 22.27 ? 1005 HOH B O 1 HETATM 12489 O O . HOH Z 8 . ? -7.274 -21.404 11.751 1.00 26.50 ? 1006 HOH B O 1 HETATM 12490 O O . HOH Z 8 . ? -31.185 -12.112 30.782 1.00 21.65 ? 1007 HOH B O 1 HETATM 12491 O O . HOH Z 8 . ? -23.247 4.767 77.053 1.00 30.60 ? 1008 HOH B O 1 HETATM 12492 O O . HOH Z 8 . ? 5.180 -23.245 30.862 1.00 41.08 ? 1009 HOH B O 1 HETATM 12493 O O . HOH Z 8 . ? -18.150 14.272 36.829 1.00 31.94 ? 1010 HOH B O 1 HETATM 12494 O O . HOH Z 8 . ? 0.799 -23.664 49.554 1.00 30.41 ? 1011 HOH B O 1 HETATM 12495 O O . HOH Z 8 . ? -11.978 -29.802 6.367 1.00 28.72 ? 1012 HOH B O 1 HETATM 12496 O O . HOH Z 8 . ? 10.557 7.013 16.807 1.00 35.82 ? 1013 HOH B O 1 HETATM 12497 O O . HOH Z 8 . ? -45.287 -19.860 14.608 1.00 47.94 ? 1014 HOH B O 1 HETATM 12498 O O . HOH Z 8 . ? -40.600 6.664 33.639 1.00 26.32 ? 1015 HOH B O 1 HETATM 12499 O O . HOH Z 8 . ? -7.820 -1.459 69.814 1.00 39.07 ? 1016 HOH B O 1 HETATM 12500 O O . HOH Z 8 . ? -19.249 -26.326 16.088 1.00 25.77 ? 1017 HOH B O 1 HETATM 12501 O O . HOH Z 8 . ? -16.836 -22.168 9.926 1.00 22.55 ? 1018 HOH B O 1 HETATM 12502 O O . HOH Z 8 . ? -0.469 3.678 9.008 1.00 32.02 ? 1019 HOH B O 1 HETATM 12503 O O . HOH Z 8 . ? -22.477 15.323 33.654 1.00 30.07 ? 1020 HOH B O 1 HETATM 12504 O O . HOH Z 8 . ? 4.885 -16.622 12.792 1.00 37.38 ? 1021 HOH B O 1 HETATM 12505 O O . HOH Z 8 . ? -39.098 -17.092 10.954 1.00 24.66 ? 1022 HOH B O 1 HETATM 12506 O O . HOH Z 8 . ? -45.488 -12.582 15.451 1.00 35.91 ? 1023 HOH B O 1 HETATM 12507 O O . HOH Z 8 . ? -30.534 -27.294 9.213 1.00 38.81 ? 1024 HOH B O 1 HETATM 12508 O O . HOH Z 8 . ? -36.696 -21.565 25.974 1.00 28.20 ? 1027 HOH B O 1 HETATM 12509 O O . HOH Z 8 . ? -9.689 -13.381 16.182 1.00 18.71 ? 1028 HOH B O 1 HETATM 12510 O O . HOH Z 8 . ? 4.225 -26.991 33.401 1.00 25.62 ? 1029 HOH B O 1 HETATM 12511 O O . HOH Z 8 . ? 14.866 -2.376 38.178 1.00 41.38 ? 1030 HOH B O 1 HETATM 12512 O O . HOH Z 8 . ? -3.218 10.013 17.368 1.00 29.24 ? 1031 HOH B O 1 HETATM 12513 O O . HOH Z 8 . ? -19.001 9.882 42.312 1.00 19.57 ? 1032 HOH B O 1 HETATM 12514 O O . HOH Z 8 . ? -22.593 16.742 20.690 1.00 39.46 ? 1033 HOH B O 1 HETATM 12515 O O . HOH Z 8 . ? -14.917 -20.276 49.029 1.00 32.61 ? 1034 HOH B O 1 HETATM 12516 O O . HOH Z 8 . ? -24.287 16.277 69.682 1.00 28.82 ? 1035 HOH B O 1 HETATM 12517 O O . HOH Z 8 . ? 7.006 9.944 15.988 1.00 47.47 ? 1036 HOH B O 1 HETATM 12518 O O . HOH Z 8 . ? -6.083 -15.969 5.843 1.00 24.25 ? 1037 HOH B O 1 HETATM 12519 O O . HOH Z 8 . ? -0.302 -33.546 43.475 1.00 39.37 ? 1038 HOH B O 1 HETATM 12520 O O . HOH Z 8 . ? -2.218 3.208 32.338 1.00 33.43 ? 1039 HOH B O 1 HETATM 12521 O O . HOH Z 8 . ? -9.178 -18.447 10.670 1.00 24.87 ? 1040 HOH B O 1 HETATM 12522 O O . HOH Z 8 . ? 7.252 5.897 34.192 1.00 49.91 ? 1041 HOH B O 1 HETATM 12523 O O . HOH Z 8 . ? 1.213 12.209 24.147 1.00 37.32 ? 1042 HOH B O 1 HETATM 12524 O O . HOH Z 8 . ? -30.996 13.931 70.863 1.00 39.70 ? 1043 HOH B O 1 HETATM 12525 O O . HOH Z 8 . ? -4.871 -13.417 28.409 1.00 28.16 ? 1044 HOH B O 1 HETATM 12526 O O . HOH Z 8 . ? 7.424 1.659 4.422 1.00 47.00 ? 1045 HOH B O 1 HETATM 12527 O O . HOH Z 8 . ? -19.083 9.398 53.151 1.00 24.77 ? 1046 HOH B O 1 HETATM 12528 O O . HOH Z 8 . ? -25.847 -8.812 -4.290 1.00 36.07 ? 1047 HOH B O 1 HETATM 12529 O O . HOH Z 8 . ? -7.899 -13.225 4.605 1.00 24.42 ? 1048 HOH B O 1 HETATM 12530 O O . HOH Z 8 . ? -3.101 -19.304 61.414 1.00 32.94 ? 1049 HOH B O 1 HETATM 12531 O O . HOH Z 8 . ? 3.475 -4.636 2.189 1.00 28.64 ? 1050 HOH B O 1 HETATM 12532 O O . HOH Z 8 . ? 1.127 -23.192 26.743 1.00 31.01 ? 1051 HOH B O 1 HETATM 12533 O O . HOH Z 8 . ? -8.475 -29.902 24.818 1.00 31.31 ? 1052 HOH B O 1 HETATM 12534 O O . HOH Z 8 . ? -24.474 15.822 41.104 1.00 31.19 ? 1053 HOH B O 1 HETATM 12535 O O . HOH Z 8 . ? -33.992 3.722 78.833 1.00 38.42 ? 1054 HOH B O 1 HETATM 12536 O O . HOH Z 8 . ? -5.490 -5.171 7.664 1.00 38.83 ? 1055 HOH B O 1 HETATM 12537 O O . HOH Z 8 . ? -22.805 0.748 11.450 1.00 38.01 ? 1056 HOH B O 1 HETATM 12538 O O . HOH Z 8 . ? -3.148 -14.477 -6.694 1.00 50.99 ? 1057 HOH B O 1 HETATM 12539 O O . HOH Z 8 . ? -0.559 -24.832 52.516 1.00 40.07 ? 1058 HOH B O 1 HETATM 12540 O O . HOH Z 8 . ? -35.249 -21.247 -13.216 1.00 35.42 ? 1059 HOH B O 1 HETATM 12541 O O . HOH Z 8 . ? 1.781 -18.685 5.614 1.00 32.80 ? 1060 HOH B O 1 HETATM 12542 O O . HOH Z 8 . ? 12.836 -8.661 42.506 1.00 39.53 ? 1061 HOH B O 1 HETATM 12543 O O . HOH Z 8 . ? -7.575 8.180 58.755 1.00 28.63 ? 1062 HOH B O 1 HETATM 12544 O O . HOH Z 8 . ? 8.442 -0.084 5.971 1.00 33.06 ? 1063 HOH B O 1 HETATM 12545 O O . HOH Z 8 . ? 8.548 -13.923 41.816 1.00 36.86 ? 1064 HOH B O 1 HETATM 12546 O O . HOH Z 8 . ? -2.776 -0.798 26.084 1.00 24.40 ? 1065 HOH B O 1 HETATM 12547 O O . HOH Z 8 . ? -40.895 -21.872 6.796 1.00 36.73 ? 1066 HOH B O 1 HETATM 12548 O O . HOH Z 8 . ? -18.345 15.371 25.048 1.00 35.64 ? 1067 HOH B O 1 HETATM 12549 O O . HOH Z 8 . ? -25.034 -30.892 69.953 1.00 37.19 ? 1068 HOH B O 1 HETATM 12550 O O . HOH Z 8 . ? -5.202 -21.233 27.336 1.00 30.08 ? 1069 HOH B O 1 HETATM 12551 O O . HOH Z 8 . ? 5.756 -2.334 49.070 1.00 34.04 ? 1070 HOH B O 1 HETATM 12552 O O . HOH Z 8 . ? -1.088 -18.754 4.208 1.00 49.50 ? 1071 HOH B O 1 HETATM 12553 O O . HOH Z 8 . ? 5.941 -13.839 17.372 1.00 39.39 ? 1072 HOH B O 1 HETATM 12554 O O . HOH Z 8 . ? -3.919 -17.915 67.859 1.00 29.46 ? 1073 HOH B O 1 HETATM 12555 O O . HOH Z 8 . ? -17.586 16.646 22.497 1.00 44.00 ? 1074 HOH B O 1 HETATM 12556 O O . HOH Z 8 . ? -31.074 11.232 38.354 1.00 46.74 ? 1075 HOH B O 1 HETATM 12557 O O . HOH Z 8 . ? -49.271 9.824 36.216 1.00 46.87 ? 1076 HOH B O 1 HETATM 12558 O O . HOH Z 8 . ? -32.954 14.125 41.248 1.00 37.73 ? 1077 HOH B O 1 HETATM 12559 O O . HOH Z 8 . ? -12.185 -3.315 28.126 1.00 30.28 ? 1078 HOH B O 1 HETATM 12560 O O . HOH Z 8 . ? -19.990 -22.118 39.792 1.00 33.49 ? 1079 HOH B O 1 HETATM 12561 O O . HOH Z 8 . ? -16.333 10.390 42.840 1.00 17.16 ? 1080 HOH B O 1 HETATM 12562 O O . HOH Z 8 . ? 4.104 -5.117 51.686 1.00 36.42 ? 1081 HOH B O 1 HETATM 12563 O O . HOH Z 8 . ? 2.097 -6.185 28.915 1.00 30.49 ? 1082 HOH B O 1 HETATM 12564 O O . HOH Z 8 . ? 5.307 -0.032 45.516 1.00 30.56 ? 1083 HOH B O 1 HETATM 12565 O O . HOH Z 8 . ? -15.224 -30.789 36.501 1.00 32.62 ? 1084 HOH B O 1 HETATM 12566 O O . HOH Z 8 . ? 11.494 -4.089 30.301 1.00 35.90 ? 1085 HOH B O 1 HETATM 12567 O O . HOH Z 8 . ? -5.705 -32.398 29.348 1.00 42.76 ? 1086 HOH B O 1 HETATM 12568 O O . HOH Z 8 . ? -27.758 17.502 62.981 1.00 25.37 ? 1087 HOH B O 1 HETATM 12569 O O . HOH Z 8 . ? -2.787 7.719 8.112 1.00 45.89 ? 1088 HOH B O 1 HETATM 12570 O O . HOH Z 8 . ? -2.829 -16.733 0.052 1.00 44.08 ? 1089 HOH B O 1 HETATM 12571 O O . HOH Z 8 . ? -19.118 15.596 67.517 1.00 28.29 ? 1090 HOH B O 1 HETATM 12572 O O . HOH Z 8 . ? -2.304 11.134 15.060 1.00 27.82 ? 1091 HOH B O 1 HETATM 12573 O O . HOH Z 8 . ? -31.414 5.650 76.123 1.00 31.54 ? 1092 HOH B O 1 HETATM 12574 O O . HOH Z 8 . ? -14.881 14.059 68.148 1.00 44.35 ? 1093 HOH B O 1 HETATM 12575 O O . HOH Z 8 . ? -38.857 -20.733 9.830 1.00 33.54 ? 1094 HOH B O 1 HETATM 12576 O O . HOH Z 8 . ? 6.070 10.916 19.013 1.00 33.74 ? 1095 HOH B O 1 HETATM 12577 O O . HOH Z 8 . ? -28.186 -7.586 40.416 1.00 31.05 ? 1096 HOH B O 1 HETATM 12578 O O . HOH Z 8 . ? -21.486 18.706 62.321 1.00 36.29 ? 1097 HOH B O 1 HETATM 12579 O O . HOH Z 8 . ? -20.868 -10.242 41.039 1.00 32.01 ? 1098 HOH B O 1 HETATM 12580 O O . HOH Z 8 . ? 2.321 -19.016 54.471 1.00 28.71 ? 1099 HOH B O 1 HETATM 12581 O O . HOH Z 8 . ? -2.560 3.648 25.530 1.00 40.58 ? 1100 HOH B O 1 HETATM 12582 O O . HOH Z 8 . ? -34.984 3.223 13.684 1.00 40.84 ? 1103 HOH B O 1 HETATM 12583 O O . HOH Z 8 . ? -22.220 -16.442 -7.110 1.00 35.76 ? 1104 HOH B O 1 HETATM 12584 O O . HOH Z 8 . ? 7.013 -0.811 47.595 1.00 30.42 ? 1105 HOH B O 1 HETATM 12585 O O . HOH Z 8 . ? -23.023 -23.305 26.542 1.00 37.15 ? 1106 HOH B O 1 HETATM 12586 O O . HOH Z 8 . ? -1.302 -10.836 32.348 1.00 21.23 ? 1107 HOH B O 1 HETATM 12587 O O . HOH Z 8 . ? -43.642 4.828 22.048 1.00 39.59 ? 1108 HOH B O 1 HETATM 12588 O O . HOH Z 8 . ? -17.457 -21.692 41.011 1.00 30.97 ? 1109 HOH B O 1 HETATM 12589 O O . HOH Z 8 . ? -18.285 15.174 15.408 1.00 44.56 ? 1110 HOH B O 1 HETATM 12590 O O . HOH Z 8 . ? -20.398 14.357 34.707 1.00 39.10 ? 1111 HOH B O 1 HETATM 12591 O O . HOH Z 8 . ? -17.196 -24.319 41.694 1.00 38.61 ? 1112 HOH B O 1 HETATM 12592 O O . HOH Z 8 . ? -43.377 -1.502 28.054 1.00 28.88 ? 1113 HOH B O 1 HETATM 12593 O O . HOH Z 8 . ? -17.746 3.277 54.148 1.00 35.92 ? 1114 HOH B O 1 HETATM 12594 O O . HOH Z 8 . ? 10.538 -6.758 46.833 1.00 41.40 ? 1115 HOH B O 1 HETATM 12595 O O . HOH Z 8 . ? -32.827 -2.667 -1.180 1.00 49.42 ? 1116 HOH B O 1 HETATM 12596 O O . HOH Z 8 . ? 4.958 10.109 26.594 1.00 43.10 ? 1117 HOH B O 1 HETATM 12597 O O . HOH Z 8 . ? -5.241 10.062 34.890 1.00 48.54 ? 1118 HOH B O 1 HETATM 12598 O O . HOH Z 8 . ? -33.913 -25.442 11.044 1.00 38.73 ? 1119 HOH B O 1 HETATM 12599 O O . HOH Z 8 . ? -3.353 5.378 50.304 1.00 35.66 ? 1120 HOH B O 1 HETATM 12600 O O . HOH Z 8 . ? -43.257 6.012 33.436 1.00 28.38 ? 1121 HOH B O 1 HETATM 12601 O O . HOH Z 8 . ? -7.178 -20.584 5.426 1.00 49.95 ? 1122 HOH B O 1 HETATM 12602 O O . HOH Z 8 . ? -24.763 -28.381 -0.055 1.00 47.14 ? 1123 HOH B O 1 HETATM 12603 O O . HOH Z 8 . ? -18.339 15.269 32.877 1.00 50.05 ? 1124 HOH B O 1 HETATM 12604 O O . HOH Z 8 . ? -20.794 -18.076 -5.126 1.00 44.40 ? 1125 HOH B O 1 HETATM 12605 O O . HOH Z 8 . ? -30.944 -15.434 -10.726 1.00 40.99 ? 1126 HOH B O 1 HETATM 12606 O O . HOH Z 8 . ? -13.353 -34.794 68.612 1.00 49.04 ? 1127 HOH B O 1 HETATM 12607 O O . HOH Z 8 . ? -37.159 2.529 16.263 1.00 38.74 ? 1128 HOH B O 1 HETATM 12608 O O . HOH Z 8 . ? -21.099 15.682 30.989 1.00 33.84 ? 1129 HOH B O 1 HETATM 12609 O O . HOH Z 8 . ? -6.465 14.113 42.218 1.00 49.07 ? 1130 HOH B O 1 HETATM 12610 O O . HOH Z 8 . ? 7.945 -9.382 4.135 1.00 40.09 ? 1131 HOH B O 1 HETATM 12611 O O . HOH Z 8 . ? 4.418 -9.698 35.138 1.00 33.88 ? 1132 HOH B O 1 HETATM 12612 O O . HOH Z 8 . ? -29.863 11.570 75.970 1.00 31.42 ? 1133 HOH B O 1 HETATM 12613 O O . HOH Z 8 . ? -10.401 12.855 40.189 1.00 27.12 ? 1134 HOH B O 1 HETATM 12614 O O . HOH Z 8 . ? -5.897 -19.955 61.239 1.00 51.04 ? 1135 HOH B O 1 HETATM 12615 O O . HOH Z 8 . ? -23.839 16.221 22.929 1.00 33.59 ? 1136 HOH B O 1 HETATM 12616 O O . HOH Z 8 . ? -25.681 4.953 45.227 1.00 30.60 ? 1137 HOH B O 1 HETATM 12617 O O . HOH Z 8 . ? 4.419 -19.474 52.892 1.00 37.48 ? 1138 HOH B O 1 HETATM 12618 O O . HOH Z 8 . ? -10.844 3.888 14.594 1.00 37.38 ? 1139 HOH B O 1 HETATM 12619 O O . HOH Z 8 . ? -9.584 2.727 16.713 1.00 36.63 ? 1140 HOH B O 1 HETATM 12620 O O . HOH Z 8 . ? -21.266 -18.066 44.252 1.00 43.89 ? 1141 HOH B O 1 HETATM 12621 O O . HOH Z 8 . ? -11.488 9.478 57.072 1.00 33.68 ? 1142 HOH B O 1 HETATM 12622 O O . HOH Z 8 . ? -21.950 0.201 77.788 1.00 33.53 ? 1143 HOH B O 1 HETATM 12623 O O . HOH Z 8 . ? -2.882 -29.505 19.587 1.00 53.38 ? 1144 HOH B O 1 HETATM 12624 O O . HOH Z 8 . ? 8.784 -27.585 42.483 1.00 37.36 ? 1145 HOH B O 1 HETATM 12625 O O . HOH Z 8 . ? 9.465 0.363 32.301 1.00 32.57 ? 1146 HOH B O 1 HETATM 12626 O O . HOH Z 8 . ? -38.989 -8.602 11.907 1.00 33.57 ? 1147 HOH B O 1 HETATM 12627 O O . HOH Z 8 . ? -11.378 4.724 52.011 1.00 38.40 ? 1148 HOH B O 1 HETATM 12628 O O . HOH Z 8 . ? -0.862 -31.748 36.965 1.00 38.51 ? 1149 HOH B O 1 HETATM 12629 O O . HOH Z 8 . ? -26.912 1.232 -1.707 1.00 27.11 ? 1150 HOH B O 1 HETATM 12630 O O . HOH Z 8 . ? -3.447 -11.876 26.944 1.00 29.70 ? 1151 HOH B O 1 HETATM 12631 O O . HOH Z 8 . ? -10.131 -7.368 15.125 1.00 29.09 ? 1152 HOH B O 1 HETATM 12632 O O . HOH Z 8 . ? -4.825 -4.042 10.153 1.00 29.61 ? 1153 HOH B O 1 HETATM 12633 O O . HOH Z 8 . ? -17.631 -26.632 14.161 1.00 38.73 ? 1154 HOH B O 1 HETATM 12634 O O . HOH Z 8 . ? -12.356 12.826 30.019 1.00 40.00 ? 1155 HOH B O 1 HETATM 12635 O O . HOH Z 8 . ? 7.495 -1.515 29.493 1.00 33.63 ? 1156 HOH B O 1 HETATM 12636 O O . HOH Z 8 . ? -5.053 -28.892 10.516 1.00 49.08 ? 1157 HOH B O 1 HETATM 12637 O O . HOH Z 8 . ? -16.748 -1.880 18.581 1.00 41.98 ? 1158 HOH B O 1 HETATM 12638 O O . HOH Z 8 . ? -9.325 -33.025 20.000 1.00 38.26 ? 1159 HOH B O 1 HETATM 12639 O O . HOH Z 8 . ? 0.484 -5.676 32.020 1.00 45.31 ? 1160 HOH B O 1 HETATM 12640 O O . HOH Z 8 . ? -9.742 -18.173 -0.121 1.00 35.29 ? 1161 HOH B O 1 HETATM 12641 O O . HOH Z 8 . ? -28.125 -26.754 10.489 1.00 34.43 ? 1162 HOH B O 1 HETATM 12642 O O . HOH Z 8 . ? -22.400 -26.652 31.283 1.00 33.49 ? 1163 HOH B O 1 HETATM 12643 O O . HOH Z 8 . ? 6.112 -17.339 7.164 1.00 37.96 ? 1164 HOH B O 1 HETATM 12644 O O . HOH Z 8 . ? -7.319 -29.242 60.980 1.00 38.33 ? 1165 HOH B O 1 HETATM 12645 O O . HOH Z 8 . ? -5.118 -9.444 7.421 1.00 25.66 ? 1166 HOH B O 1 HETATM 12646 O O . HOH Z 8 . ? -1.984 -19.114 16.627 1.00 33.13 ? 1167 HOH B O 1 HETATM 12647 O O . HOH Z 8 . ? -42.485 -1.211 19.842 1.00 40.12 ? 1168 HOH B O 1 HETATM 12648 O O . HOH Z 8 . ? 8.369 -13.990 0.070 1.00 51.09 ? 1169 HOH B O 1 HETATM 12649 O O . HOH Z 8 . ? -15.118 -25.428 15.372 1.00 40.57 ? 1170 HOH B O 1 HETATM 12650 O O . HOH Z 8 . ? 1.055 -4.821 -1.734 1.00 44.17 ? 1171 HOH B O 1 HETATM 12651 O O . HOH Z 8 . ? 1.802 -9.802 33.945 1.00 36.71 ? 1172 HOH B O 1 HETATM 12652 O O . HOH Z 8 . ? -17.975 -16.208 54.830 1.00 36.53 ? 1173 HOH B O 1 HETATM 12653 O O . HOH Z 8 . ? -30.032 -2.844 -8.318 1.00 29.14 ? 1174 HOH B O 1 HETATM 12654 O O . HOH Z 8 . ? -44.698 4.263 31.987 1.00 46.05 ? 1175 HOH B O 1 HETATM 12655 O O . HOH Z 8 . ? 1.388 -6.511 26.075 1.00 38.64 ? 1176 HOH B O 1 HETATM 12656 O O . HOH Z 8 . ? 1.308 -23.071 6.014 1.00 46.13 ? 1177 HOH B O 1 HETATM 12657 O O . HOH Z 8 . ? -3.341 -30.656 55.004 1.00 37.65 ? 1178 HOH B O 1 HETATM 12658 O O . HOH Z 8 . ? 15.253 1.361 6.240 1.00 43.52 ? 1179 HOH B O 1 HETATM 12659 O O . HOH Z 8 . ? -25.936 15.586 64.178 1.00 42.04 ? 1180 HOH B O 1 HETATM 12660 O O . HOH Z 8 . ? -17.427 -26.712 50.282 1.00 34.72 ? 1181 HOH B O 1 HETATM 12661 O O . HOH Z 8 . ? -28.118 1.423 5.073 1.00 39.35 ? 1182 HOH B O 1 HETATM 12662 O O . HOH Z 8 . ? -11.819 -8.778 56.154 1.00 35.04 ? 1183 HOH B O 1 HETATM 12663 O O . HOH Z 8 . ? 4.377 -13.034 52.703 1.00 35.08 ? 1184 HOH B O 1 HETATM 12664 O O . HOH Z 8 . ? 2.752 -11.417 23.047 1.00 55.94 ? 1185 HOH B O 1 HETATM 12665 O O . HOH Z 8 . ? -15.231 -26.375 42.391 1.00 43.94 ? 1186 HOH B O 1 HETATM 12666 O O . HOH Z 8 . ? -12.120 16.289 47.842 1.00 28.30 ? 1187 HOH B O 1 HETATM 12667 O O . HOH Z 8 . ? -1.985 14.264 22.256 1.00 47.54 ? 1188 HOH B O 1 HETATM 12668 O O . HOH Z 8 . ? 1.167 -0.558 9.551 1.00 43.44 ? 1189 HOH B O 1 HETATM 12669 O O . HOH Z 8 . ? -43.420 -22.568 14.460 1.00 37.43 ? 1190 HOH B O 1 HETATM 12670 O O . HOH Z 8 . ? -16.940 16.489 42.276 1.00 40.22 ? 1191 HOH B O 1 HETATM 12671 O O . HOH Z 8 . ? -5.261 -30.510 27.277 1.00 37.31 ? 1192 HOH B O 1 HETATM 12672 O O . HOH Z 8 . ? 0.897 13.980 22.432 1.00 40.92 ? 1193 HOH B O 1 HETATM 12673 O O . HOH Z 8 . ? -2.895 6.242 26.445 1.00 46.32 ? 1194 HOH B O 1 HETATM 12674 O O . HOH Z 8 . ? -35.902 -27.301 24.269 1.00 42.35 ? 1195 HOH B O 1 HETATM 12675 O O . HOH Z 8 . ? 12.390 1.242 46.599 1.00 51.60 ? 1196 HOH B O 1 HETATM 12676 O O . HOH Z 8 . ? -19.780 14.508 57.258 1.00 40.72 ? 1197 HOH B O 1 HETATM 12677 O O . HOH Z 8 . ? -2.506 9.079 43.238 1.00 38.75 ? 1198 HOH B O 1 HETATM 12678 O O . HOH Z 8 . ? -12.830 5.988 53.902 1.00 45.05 ? 1199 HOH B O 1 HETATM 12679 O O . HOH Z 8 . ? -2.784 -32.213 32.183 1.00 50.31 ? 1200 HOH B O 1 HETATM 12680 O O . HOH Z 8 . ? -44.896 -0.287 20.818 1.00 47.86 ? 1201 HOH B O 1 HETATM 12681 O O . HOH Z 8 . ? -0.144 -17.240 15.750 1.00 40.98 ? 1202 HOH B O 1 HETATM 12682 O O . HOH Z 8 . ? -25.452 -10.731 39.684 1.00 34.14 ? 1203 HOH B O 1 HETATM 12683 O O . HOH Z 8 . ? 3.511 -23.723 53.376 1.00 40.25 ? 1204 HOH B O 1 HETATM 12684 O O . HOH Z 8 . ? 2.388 -20.714 2.537 1.00 49.45 ? 1205 HOH B O 1 HETATM 12685 O O . HOH Z 8 . ? -3.422 -21.823 6.897 1.00 38.12 ? 1206 HOH B O 1 HETATM 12686 O O . HOH Z 8 . ? 8.902 6.714 10.092 1.00 53.11 ? 1207 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 21 ? ? ? A . n A 1 2 SER 2 22 ? ? ? A . n A 1 3 PRO 3 23 ? ? ? A . n A 1 4 GLY 4 24 ? ? ? A . n A 1 5 THR 5 25 ? ? ? A . n A 1 6 LEU 6 26 ? ? ? A . n A 1 7 PRO 7 27 27 PRO PRO A . n A 1 8 ARG 8 28 28 ARG ARG A . n A 1 9 LYS 9 29 29 LYS LYS A . n A 1 10 ALA 10 30 30 ALA ALA A . n A 1 11 GLY 11 31 31 GLY GLY A . n A 1 12 VAL 12 32 32 VAL VAL A . n A 1 13 PHE 13 33 33 PHE PHE A . n A 1 14 SER 14 34 34 SER SER A . n A 1 15 ASP 15 35 35 ASP ASP A . n A 1 16 LEU 16 36 36 LEU LEU A . n A 1 17 SER 17 37 37 SER SER A . n A 1 18 ASN 18 38 38 ASN ASN A . n A 1 19 GLN 19 39 39 GLN GLN A . n A 1 20 GLU 20 40 40 GLU GLU A . n A 1 21 LEU 21 41 41 LEU LEU A . n A 1 22 LYS 22 42 42 LYS LYS A . n A 1 23 ALA 23 43 43 ALA ALA A . n A 1 24 VAL 24 44 44 VAL VAL A . n A 1 25 HIS 25 45 45 HIS HIS A . n A 1 26 SER 26 46 46 SER SER A . n A 1 27 PHE 27 47 47 PHE PHE A . n A 1 28 LEU 28 48 48 LEU LEU A . n A 1 29 TRP 29 49 49 TRP TRP A . n A 1 30 SER 30 50 50 SER SER A . n A 1 31 LYS 31 51 51 LYS LYS A . n A 1 32 LYS 32 52 52 LYS LYS A . n A 1 33 GLU 33 53 53 GLU GLU A . n A 1 34 LEU 34 54 54 LEU LEU A . n A 1 35 ARG 35 55 55 ARG ARG A . n A 1 36 LEU 36 56 56 LEU LEU A . n A 1 37 GLN 37 57 57 GLN GLN A . n A 1 38 PRO 38 58 58 PRO PRO A . n A 1 39 SER 39 59 59 SER SER A . n A 1 40 SER 40 60 60 SER SER A . n A 1 41 THR 41 61 61 THR THR A . n A 1 42 THR 42 62 62 THR THR A . n A 1 43 THR 43 63 63 THR THR A . n A 1 44 MET 44 64 64 MET MET A . n A 1 45 ALA 45 65 65 ALA ALA A . n A 1 46 LYS 46 66 66 LYS LYS A . n A 1 47 ASN 47 67 67 ASN ASN A . n A 1 48 THR 48 68 68 THR THR A . n A 1 49 VAL 49 69 69 VAL VAL A . n A 1 50 PHE 50 70 70 PHE PHE A . n A 1 51 LEU 51 71 71 LEU LEU A . n A 1 52 ILE 52 72 72 ILE ILE A . n A 1 53 GLU 53 73 73 GLU GLU A . n A 1 54 MET 54 74 74 MET MET A . n A 1 55 LEU 55 75 75 LEU LEU A . n A 1 56 LEU 56 76 76 LEU LEU A . n A 1 57 PRO 57 77 77 PRO PRO A . n A 1 58 LYS 58 78 78 LYS LYS A . n A 1 59 LYS 59 79 79 LYS LYS A . n A 1 60 TYR 60 80 80 TYR TYR A . n A 1 61 HIS 61 81 81 HIS HIS A . n A 1 62 VAL 62 82 82 VAL VAL A . n A 1 63 LEU 63 83 83 LEU LEU A . n A 1 64 ARG 64 84 84 ARG ARG A . n A 1 65 PHE 65 85 85 PHE PHE A . n A 1 66 LEU 66 86 86 LEU LEU A . n A 1 67 ASP 67 87 87 ASP ASP A . n A 1 68 LYS 68 88 88 LYS LYS A . n A 1 69 GLY 69 89 89 GLY GLY A . n A 1 70 GLU 70 90 90 GLU GLU A . n A 1 71 ARG 71 91 91 ARG ARG A . n A 1 72 HIS 72 92 92 HIS HIS A . n A 1 73 PRO 73 93 93 PRO PRO A . n A 1 74 VAL 74 94 94 VAL VAL A . n A 1 75 ARG 75 95 95 ARG ARG A . n A 1 76 GLU 76 96 96 GLU GLU A . n A 1 77 ALA 77 97 97 ALA ALA A . n A 1 78 ARG 78 98 98 ARG ARG A . n A 1 79 ALA 79 99 99 ALA ALA A . n A 1 80 VAL 80 100 100 VAL VAL A . n A 1 81 ILE 81 101 101 ILE ILE A . n A 1 82 PHE 82 102 102 PHE PHE A . n A 1 83 PHE 83 103 103 PHE PHE A . n A 1 84 GLY 84 104 104 GLY GLY A . n A 1 85 ASP 85 105 105 ASP ASP A . n A 1 86 GLN 86 106 106 GLN GLN A . n A 1 87 GLU 87 107 107 GLU GLU A . n A 1 88 HIS 88 108 108 HIS HIS A . n A 1 89 PRO 89 109 109 PRO PRO A . n A 1 90 ASN 90 110 110 ASN ASN A . n A 1 91 VAL 91 111 111 VAL VAL A . n A 1 92 THR 92 112 112 THR THR A . n A 1 93 GLU 93 113 113 GLU GLU A . n A 1 94 PHE 94 114 114 PHE PHE A . n A 1 95 ALA 95 115 115 ALA ALA A . n A 1 96 VAL 96 116 116 VAL VAL A . n A 1 97 GLY 97 117 117 GLY GLY A . n A 1 98 PRO 98 118 118 PRO PRO A . n A 1 99 LEU 99 119 119 LEU LEU A . n A 1 100 PRO 100 120 120 PRO PRO A . n A 1 101 GLY 101 121 121 GLY GLY A . n A 1 102 PRO 102 122 122 PRO PRO A . n A 1 103 CYS 103 123 123 CYS CYS A . n A 1 104 TYR 104 124 124 TYR TYR A . n A 1 105 MET 105 125 125 MET MET A . n A 1 106 ARG 106 126 126 ARG ARG A . n A 1 107 ALA 107 127 127 ALA ALA A . n A 1 108 LEU 108 128 128 LEU LEU A . n A 1 109 SER 109 129 129 SER SER A . n A 1 110 PRO 110 130 130 PRO PRO A . n A 1 111 ARG 111 131 131 ARG ARG A . n A 1 112 PRO 112 132 132 PRO PRO A . n A 1 113 GLY 113 133 133 GLY GLY A . n A 1 114 TYR 114 134 134 TYR TYR A . n A 1 115 GLN 115 135 135 GLN GLN A . n A 1 116 SER 116 136 136 SER SER A . n A 1 117 SER 117 137 137 SER SER A . n A 1 118 TRP 118 138 138 TRP TRP A . n A 1 119 ALA 119 139 139 ALA ALA A . n A 1 120 SER 120 140 140 SER SER A . n A 1 121 ARG 121 141 141 ARG ARG A . n A 1 122 PRO 122 142 142 PRO PRO A . n A 1 123 ILE 123 143 143 ILE ILE A . n A 1 124 SER 124 144 144 SER SER A . n A 1 125 THR 125 145 145 THR THR A . n A 1 126 ALA 126 146 146 ALA ALA A . n A 1 127 GLU 127 147 147 GLU GLU A . n A 1 128 TYR 128 148 148 TYR TYR A . n A 1 129 ALA 129 149 149 ALA ALA A . n A 1 130 LEU 130 150 150 LEU LEU A . n A 1 131 LEU 131 151 151 LEU LEU A . n A 1 132 TYR 132 152 152 TYR TYR A . n A 1 133 HIS 133 153 153 HIS HIS A . n A 1 134 THR 134 154 154 THR THR A . n A 1 135 LEU 135 155 155 LEU LEU A . n A 1 136 GLN 136 156 156 GLN GLN A . n A 1 137 GLU 137 157 157 GLU GLU A . n A 1 138 ALA 138 158 158 ALA ALA A . n A 1 139 THR 139 159 159 THR THR A . n A 1 140 LYS 140 160 160 LYS LYS A . n A 1 141 PRO 141 161 161 PRO PRO A . n A 1 142 LEU 142 162 162 LEU LEU A . n A 1 143 HIS 143 163 163 HIS HIS A . n A 1 144 GLN 144 164 164 GLN GLN A . n A 1 145 PHE 145 165 165 PHE PHE A . n A 1 146 PHE 146 166 166 PHE PHE A . n A 1 147 LEU 147 167 167 LEU LEU A . n A 1 148 ASN 148 168 168 ASN ASN A . n A 1 149 THR 149 169 169 THR THR A . n A 1 150 THR 150 170 170 THR THR A . n A 1 151 GLY 151 171 171 GLY GLY A . n A 1 152 PHE 152 172 172 PHE PHE A . n A 1 153 SER 153 173 173 SER SER A . n A 1 154 PHE 154 174 174 PHE PHE A . n A 1 155 GLN 155 175 175 GLN GLN A . n A 1 156 ASP 156 176 176 ASP ASP A . n A 1 157 CYS 157 177 177 CYS CYS A . n A 1 158 HIS 158 178 178 HIS HIS A . n A 1 159 ASP 159 179 179 ASP ASP A . n A 1 160 ARG 160 180 180 ARG ARG A . n A 1 161 CYS 161 181 181 CYS CYS A . n A 1 162 LEU 162 182 182 LEU LEU A . n A 1 163 ALA 163 183 183 ALA ALA A . n A 1 164 PHE 164 184 184 PHE PHE A . n A 1 165 THR 165 185 185 THR THR A . n A 1 166 ASP 166 186 186 ASP ASP A . n A 1 167 VAL 167 187 187 VAL VAL A . n A 1 168 ALA 168 188 188 ALA ALA A . n A 1 169 PRO 169 189 189 PRO PRO A . n A 1 170 ARG 170 190 190 ARG ARG A . n A 1 171 GLY 171 191 191 GLY GLY A . n A 1 172 VAL 172 192 192 VAL VAL A . n A 1 173 ALA 173 193 193 ALA ALA A . n A 1 174 SER 174 194 194 SER SER A . n A 1 175 GLY 175 195 195 GLY GLY A . n A 1 176 GLN 176 196 196 GLN GLN A . n A 1 177 ARG 177 197 197 ARG ARG A . n A 1 178 ARG 178 198 198 ARG ARG A . n A 1 179 SER 179 199 199 SER SER A . n A 1 180 TRP 180 200 200 TRP TRP A . n A 1 181 LEU 181 201 201 LEU LEU A . n A 1 182 ILE 182 202 202 ILE ILE A . n A 1 183 ILE 183 203 203 ILE ILE A . n A 1 184 GLN 184 204 204 GLN GLN A . n A 1 185 ARG 185 205 205 ARG ARG A . n A 1 186 TYR 186 206 206 TYR TYR A . n A 1 187 VAL 187 207 207 VAL VAL A . n A 1 188 GLU 188 208 208 GLU GLU A . n A 1 189 GLY 189 209 209 GLY GLY A . n A 1 190 TYR 190 210 210 TYR TYR A . n A 1 191 PHE 191 211 211 PHE PHE A . n A 1 192 LEU 192 212 212 LEU LEU A . n A 1 193 HIS 193 213 213 HIS HIS A . n A 1 194 PRO 194 214 214 PRO PRO A . n A 1 195 THR 195 215 215 THR THR A . n A 1 196 GLY 196 216 216 GLY GLY A . n A 1 197 LEU 197 217 217 LEU LEU A . n A 1 198 GLU 198 218 218 GLU GLU A . n A 1 199 LEU 199 219 219 LEU LEU A . n A 1 200 LEU 200 220 220 LEU LEU A . n A 1 201 VAL 201 221 221 VAL VAL A . n A 1 202 ASP 202 222 222 ASP ASP A . n A 1 203 HIS 203 223 223 HIS HIS A . n A 1 204 GLY 204 224 224 GLY GLY A . n A 1 205 SER 205 225 225 SER SER A . n A 1 206 THR 206 226 226 THR THR A . n A 1 207 ASP 207 227 227 ASP ASP A . n A 1 208 ALA 208 228 228 ALA ALA A . n A 1 209 GLY 209 229 229 GLY GLY A . n A 1 210 HIS 210 230 230 HIS HIS A . n A 1 211 TRP 211 231 231 TRP TRP A . n A 1 212 ALA 212 232 232 ALA ALA A . n A 1 213 VAL 213 233 233 VAL VAL A . n A 1 214 GLU 214 234 234 GLU GLU A . n A 1 215 GLN 215 235 235 GLN GLN A . n A 1 216 VAL 216 236 236 VAL VAL A . n A 1 217 TRP 217 237 237 TRP TRP A . n A 1 218 TYR 218 238 238 TYR TYR A . n A 1 219 ASN 219 239 239 ASN ASN A . n A 1 220 GLY 220 240 240 GLY GLY A . n A 1 221 LYS 221 241 241 LYS LYS A . n A 1 222 PHE 222 242 242 PHE PHE A . n A 1 223 TYR 223 243 243 TYR TYR A . n A 1 224 GLY 224 244 244 GLY GLY A . n A 1 225 SER 225 245 245 SER SER A . n A 1 226 PRO 226 246 246 PRO PRO A . n A 1 227 GLU 227 247 247 GLU GLU A . n A 1 228 GLU 228 248 248 GLU GLU A . n A 1 229 LEU 229 249 249 LEU LEU A . n A 1 230 ALA 230 250 250 ALA ALA A . n A 1 231 ARG 231 251 251 ARG ARG A . n A 1 232 LYS 232 252 252 LYS LYS A . n A 1 233 TYR 233 253 253 TYR TYR A . n A 1 234 ALA 234 254 254 ALA ALA A . n A 1 235 ASP 235 255 255 ASP ASP A . n A 1 236 GLY 236 256 256 GLY GLY A . n A 1 237 GLU 237 257 257 GLU GLU A . n A 1 238 VAL 238 258 258 VAL VAL A . n A 1 239 ASP 239 259 259 ASP ASP A . n A 1 240 VAL 240 260 260 VAL VAL A . n A 1 241 VAL 241 261 261 VAL VAL A . n A 1 242 VAL 242 262 262 VAL VAL A . n A 1 243 LEU 243 263 263 LEU LEU A . n A 1 244 GLU 244 264 264 GLU GLU A . n A 1 245 ASP 245 265 265 ASP ASP A . n A 1 246 PRO 246 266 266 PRO PRO A . n A 1 247 LEU 247 267 267 LEU LEU A . n A 1 248 PRO 248 268 ? ? ? A . n A 1 249 GLY 249 269 ? ? ? A . n A 1 250 GLY 250 270 ? ? ? A . n A 1 251 LYS 251 271 ? ? ? A . n A 1 252 GLY 252 272 ? ? ? A . n A 1 253 HIS 253 273 ? ? ? A . n A 1 254 ASP 254 274 ? ? ? A . n A 1 255 SER 255 275 ? ? ? A . n A 1 256 THR 256 276 ? ? ? A . n A 1 257 GLU 257 277 ? ? ? A . n A 1 258 GLU 258 278 278 GLU GLU A . n A 1 259 PRO 259 279 279 PRO PRO A . n A 1 260 PRO 260 280 280 PRO PRO A . n A 1 261 LEU 261 281 281 LEU LEU A . n A 1 262 PHE 262 282 282 PHE PHE A . n A 1 263 SER 263 283 283 SER SER A . n A 1 264 SER 264 284 284 SER SER A . n A 1 265 HIS 265 285 285 HIS HIS A . n A 1 266 LYS 266 286 286 LYS LYS A . n A 1 267 PRO 267 287 287 PRO PRO A . n A 1 268 ARG 268 288 288 ARG ARG A . n A 1 269 GLY 269 289 289 GLY GLY A . n A 1 270 ASP 270 290 290 ASP ASP A . n A 1 271 PHE 271 291 291 PHE PHE A . n A 1 272 PRO 272 292 292 PRO PRO A . n A 1 273 SER 273 293 293 SER SER A . n A 1 274 PRO 274 294 294 PRO PRO A . n A 1 275 ILE 275 295 295 ILE ILE A . n A 1 276 HIS 276 296 296 HIS HIS A . n A 1 277 VAL 277 297 297 VAL VAL A . n A 1 278 SER 278 298 298 SER SER A . n A 1 279 GLY 279 299 299 GLY GLY A . n A 1 280 PRO 280 300 300 PRO PRO A . n A 1 281 ARG 281 301 301 ARG ARG A . n A 1 282 LEU 282 302 302 LEU LEU A . n A 1 283 VAL 283 303 303 VAL VAL A . n A 1 284 GLN 284 304 304 GLN GLN A . n A 1 285 PRO 285 305 305 PRO PRO A . n A 1 286 HIS 286 306 306 HIS HIS A . n A 1 287 GLY 287 307 307 GLY GLY A . n A 1 288 PRO 288 308 308 PRO PRO A . n A 1 289 ARG 289 309 309 ARG ARG A . n A 1 290 PHE 290 310 310 PHE PHE A . n A 1 291 ARG 291 311 311 ARG ARG A . n A 1 292 LEU 292 312 312 LEU LEU A . n A 1 293 GLU 293 313 313 GLU GLU A . n A 1 294 GLY 294 314 314 GLY GLY A . n A 1 295 ASN 295 315 315 ASN ASN A . n A 1 296 ALA 296 316 316 ALA ALA A . n A 1 297 VAL 297 317 317 VAL VAL A . n A 1 298 LEU 298 318 318 LEU LEU A . n A 1 299 TYR 299 319 319 TYR TYR A . n A 1 300 GLY 300 320 320 GLY GLY A . n A 1 301 GLY 301 321 321 GLY GLY A . n A 1 302 TRP 302 322 322 TRP TRP A . n A 1 303 SER 303 323 323 SER SER A . n A 1 304 PHE 304 324 324 PHE PHE A . n A 1 305 ALA 305 325 325 ALA ALA A . n A 1 306 PHE 306 326 326 PHE PHE A . n A 1 307 ARG 307 327 327 ARG ARG A . n A 1 308 LEU 308 328 328 LEU LEU A . n A 1 309 ARG 309 329 329 ARG ARG A . n A 1 310 SER 310 330 330 SER SER A . n A 1 311 SER 311 331 331 SER SER A . n A 1 312 SER 312 332 332 SER SER A . n A 1 313 GLY 313 333 333 GLY GLY A . n A 1 314 LEU 314 334 334 LEU LEU A . n A 1 315 GLN 315 335 335 GLN GLN A . n A 1 316 VAL 316 336 336 VAL VAL A . n A 1 317 LEU 317 337 337 LEU LEU A . n A 1 318 ASN 318 338 338 ASN ASN A . n A 1 319 VAL 319 339 339 VAL VAL A . n A 1 320 HIS 320 340 340 HIS HIS A . n A 1 321 PHE 321 341 341 PHE PHE A . n A 1 322 GLY 322 342 342 GLY GLY A . n A 1 323 GLY 323 343 343 GLY GLY A . n A 1 324 GLU 324 344 344 GLU GLU A . n A 1 325 ARG 325 345 345 ARG ARG A . n A 1 326 ILE 326 346 346 ILE ILE A . n A 1 327 ALA 327 347 347 ALA ALA A . n A 1 328 TYR 328 348 348 TYR TYR A . n A 1 329 GLU 329 349 349 GLU GLU A . n A 1 330 VAL 330 350 350 VAL VAL A . n A 1 331 SER 331 351 351 SER SER A . n A 1 332 VAL 332 352 352 VAL VAL A . n A 1 333 GLN 333 353 353 GLN GLN A . n A 1 334 GLU 334 354 354 GLU GLU A . n A 1 335 ALA 335 355 355 ALA ALA A . n A 1 336 VAL 336 356 356 VAL VAL A . n A 1 337 ALA 337 357 357 ALA ALA A . n A 1 338 LEU 338 358 358 LEU LEU A . n A 1 339 TYR 339 359 359 TYR TYR A . n A 1 340 GLY 340 360 360 GLY GLY A . n A 1 341 GLY 341 361 361 GLY GLY A . n A 1 342 HIS 342 362 362 HIS HIS A . n A 1 343 THR 343 363 363 THR THR A . n A 1 344 PRO 344 364 364 PRO PRO A . n A 1 345 ALA 345 365 365 ALA ALA A . n A 1 346 GLY 346 366 366 GLY GLY A . n A 1 347 MET 347 367 367 MET MET A . n A 1 348 GLN 348 368 368 GLN GLN A . n A 1 349 THR 349 369 369 THR THR A . n A 1 350 LYS 350 370 370 LYS LYS A . n A 1 351 TYR 351 371 371 TYR TYR A . n A 1 352 LEU 352 372 372 LEU LEU A . n A 1 353 ASP 353 373 373 ASP ASP A . n A 1 354 VAL 354 374 374 VAL VAL A . n A 1 355 GLY 355 375 375 GLY GLY A . n A 1 356 TRP 356 376 376 TRP TRP A . n A 1 357 GLY 357 377 377 GLY GLY A . n A 1 358 LEU 358 378 378 LEU LEU A . n A 1 359 GLY 359 379 379 GLY GLY A . n A 1 360 SER 360 380 380 SER SER A . n A 1 361 VAL 361 381 381 VAL VAL A . n A 1 362 THR 362 382 382 THR THR A . n A 1 363 HIS 363 383 383 HIS HIS A . n A 1 364 GLU 364 384 384 GLU GLU A . n A 1 365 LEU 365 385 385 LEU LEU A . n A 1 366 ALA 366 386 386 ALA ALA A . n A 1 367 PRO 367 387 387 PRO PRO A . n A 1 368 GLY 368 388 388 GLY GLY A . n A 1 369 ILE 369 389 389 ILE ILE A . n A 1 370 ASP 370 390 390 ASP ASP A . n A 1 371 CYS 371 391 391 CYS CYS A . n A 1 372 PRO 372 392 392 PRO PRO A . n A 1 373 GLU 373 393 393 GLU GLU A . n A 1 374 THR 374 394 394 THR THR A . n A 1 375 ALA 375 395 395 ALA ALA A . n A 1 376 THR 376 396 396 THR THR A . n A 1 377 PHE 377 397 397 PHE PHE A . n A 1 378 LEU 378 398 398 LEU LEU A . n A 1 379 ASP 379 399 399 ASP ASP A . n A 1 380 THR 380 400 400 THR THR A . n A 1 381 PHE 381 401 401 PHE PHE A . n A 1 382 HIS 382 402 402 HIS HIS A . n A 1 383 TYR 383 403 403 TYR TYR A . n A 1 384 TYR 384 404 404 TYR TYR A . n A 1 385 ASP 385 405 405 ASP ASP A . n A 1 386 ALA 386 406 406 ALA ALA A . n A 1 387 ASP 387 407 407 ASP ASP A . n A 1 388 ASP 388 408 408 ASP ASP A . n A 1 389 PRO 389 409 409 PRO PRO A . n A 1 390 VAL 390 410 410 VAL VAL A . n A 1 391 HIS 391 411 411 HIS HIS A . n A 1 392 TYR 392 412 412 TYR TYR A . n A 1 393 PRO 393 413 413 PRO PRO A . n A 1 394 ARG 394 414 414 ARG ARG A . n A 1 395 ALA 395 415 415 ALA ALA A . n A 1 396 LEU 396 416 416 LEU LEU A . n A 1 397 CYS 397 417 417 CYS CYS A . n A 1 398 LEU 398 418 418 LEU LEU A . n A 1 399 PHE 399 419 419 PHE PHE A . n A 1 400 GLU 400 420 420 GLU GLU A . n A 1 401 MET 401 421 421 MET MET A . n A 1 402 PRO 402 422 422 PRO PRO A . n A 1 403 THR 403 423 423 THR THR A . n A 1 404 GLY 404 424 424 GLY GLY A . n A 1 405 VAL 405 425 425 VAL VAL A . n A 1 406 PRO 406 426 426 PRO PRO A . n A 1 407 LEU 407 427 427 LEU LEU A . n A 1 408 ARG 408 428 428 ARG ARG A . n A 1 409 ARG 409 429 429 ARG ARG A . n A 1 410 HIS 410 430 430 HIS HIS A . n A 1 411 PHE 411 431 431 PHE PHE A . n A 1 412 ASN 412 432 432 ASN ASN A . n A 1 413 SER 413 433 433 SER SER A . n A 1 414 ASN 414 434 434 ASN ASN A . n A 1 415 PHE 415 435 435 PHE PHE A . n A 1 416 LYS 416 436 436 LYS LYS A . n A 1 417 GLY 417 437 437 GLY GLY A . n A 1 418 GLY 418 438 438 GLY GLY A . n A 1 419 PHE 419 439 439 PHE PHE A . n A 1 420 ASN 420 440 440 ASN ASN A . n A 1 421 PHE 421 441 441 PHE PHE A . n A 1 422 TYR 422 442 442 TYR TYR A . n A 1 423 ALA 423 443 443 ALA ALA A . n A 1 424 GLY 424 444 444 GLY GLY A . n A 1 425 LEU 425 445 445 LEU LEU A . n A 1 426 LYS 426 446 446 LYS LYS A . n A 1 427 GLY 427 447 447 GLY GLY A . n A 1 428 GLN 428 448 448 GLN GLN A . n A 1 429 VAL 429 449 449 VAL VAL A . n A 1 430 LEU 430 450 450 LEU LEU A . n A 1 431 VAL 431 451 451 VAL VAL A . n A 1 432 LEU 432 452 452 LEU LEU A . n A 1 433 ARG 433 453 453 ARG ARG A . n A 1 434 THR 434 454 454 THR THR A . n A 1 435 THR 435 455 455 THR THR A . n A 1 436 SER 436 456 456 SER SER A . n A 1 437 THR 437 457 457 THR THR A . n A 1 438 VAL 438 458 458 VAL VAL A . n A 1 439 TYR 439 459 459 TYR TYR A . n A 1 440 ASN 440 460 460 ASN ASN A . n A 1 441 TPQ 441 461 461 TPQ TPQ A . n A 1 442 ASP 442 462 462 ASP ASP A . n A 1 443 TYR 443 463 463 TYR TYR A . n A 1 444 ILE 444 464 464 ILE ILE A . n A 1 445 TRP 445 465 465 TRP TRP A . n A 1 446 ASP 446 466 466 ASP ASP A . n A 1 447 PHE 447 467 467 PHE PHE A . n A 1 448 ILE 448 468 468 ILE ILE A . n A 1 449 PHE 449 469 469 PHE PHE A . n A 1 450 TYR 450 470 470 TYR TYR A . n A 1 451 PRO 451 471 471 PRO PRO A . n A 1 452 ASN 452 472 472 ASN ASN A . n A 1 453 GLY 453 473 473 GLY GLY A . n A 1 454 VAL 454 474 474 VAL VAL A . n A 1 455 MET 455 475 475 MET MET A . n A 1 456 GLU 456 476 476 GLU GLU A . n A 1 457 ALA 457 477 477 ALA ALA A . n A 1 458 LYS 458 478 478 LYS LYS A . n A 1 459 MET 459 479 479 MET MET A . n A 1 460 HIS 460 480 480 HIS HIS A . n A 1 461 ALA 461 481 481 ALA ALA A . n A 1 462 THR 462 482 482 THR THR A . n A 1 463 GLY 463 483 483 GLY GLY A . n A 1 464 TYR 464 484 484 TYR TYR A . n A 1 465 VAL 465 485 485 VAL VAL A . n A 1 466 HIS 466 486 486 HIS HIS A . n A 1 467 ALA 467 487 487 ALA ALA A . n A 1 468 THR 468 488 488 THR THR A . n A 1 469 PHE 469 489 489 PHE PHE A . n A 1 470 TYR 470 490 490 TYR TYR A . n A 1 471 THR 471 491 491 THR THR A . n A 1 472 PRO 472 492 492 PRO PRO A . n A 1 473 GLU 473 493 493 GLU GLU A . n A 1 474 GLY 474 494 494 GLY GLY A . n A 1 475 LEU 475 495 495 LEU LEU A . n A 1 476 ARG 476 496 496 ARG ARG A . n A 1 477 HIS 477 497 497 HIS HIS A . n A 1 478 GLY 478 498 498 GLY GLY A . n A 1 479 THR 479 499 499 THR THR A . n A 1 480 ARG 480 500 500 ARG ARG A . n A 1 481 LEU 481 501 501 LEU LEU A . n A 1 482 HIS 482 502 502 HIS HIS A . n A 1 483 THR 483 503 503 THR THR A . n A 1 484 HIS 484 504 504 HIS HIS A . n A 1 485 LEU 485 505 505 LEU LEU A . n A 1 486 ILE 486 506 506 ILE ILE A . n A 1 487 GLY 487 507 507 GLY GLY A . n A 1 488 ASN 488 508 508 ASN ASN A . n A 1 489 ILE 489 509 509 ILE ILE A . n A 1 490 HIS 490 510 510 HIS HIS A . n A 1 491 THR 491 511 511 THR THR A . n A 1 492 HIS 492 512 512 HIS HIS A . n A 1 493 LEU 493 513 513 LEU LEU A . n A 1 494 VAL 494 514 514 VAL VAL A . n A 1 495 HIS 495 515 515 HIS HIS A . n A 1 496 TYR 496 516 516 TYR TYR A . n A 1 497 ARG 497 517 517 ARG ARG A . n A 1 498 VAL 498 518 518 VAL VAL A . n A 1 499 ASP 499 519 519 ASP ASP A . n A 1 500 LEU 500 520 520 LEU LEU A . n A 1 501 ASP 501 521 521 ASP ASP A . n A 1 502 VAL 502 522 522 VAL VAL A . n A 1 503 ALA 503 523 523 ALA ALA A . n A 1 504 GLY 504 524 524 GLY GLY A . n A 1 505 THR 505 525 525 THR THR A . n A 1 506 LYS 506 526 526 LYS LYS A . n A 1 507 ASN 507 527 527 ASN ASN A . n A 1 508 SER 508 528 528 SER SER A . n A 1 509 PHE 509 529 529 PHE PHE A . n A 1 510 GLN 510 530 530 GLN GLN A . n A 1 511 THR 511 531 531 THR THR A . n A 1 512 LEU 512 532 532 LEU LEU A . n A 1 513 GLN 513 533 533 GLN GLN A . n A 1 514 MET 514 534 534 MET MET A . n A 1 515 LYS 515 535 535 LYS LYS A . n A 1 516 LEU 516 536 536 LEU LEU A . n A 1 517 GLU 517 537 537 GLU GLU A . n A 1 518 ASN 518 538 538 ASN ASN A . n A 1 519 ILE 519 539 539 ILE ILE A . n A 1 520 THR 520 540 540 THR THR A . n A 1 521 ASN 521 541 541 ASN ASN A . n A 1 522 PRO 522 542 542 PRO PRO A . n A 1 523 TRP 523 543 543 TRP TRP A . n A 1 524 SER 524 544 544 SER SER A . n A 1 525 PRO 525 545 545 PRO PRO A . n A 1 526 ARG 526 546 546 ARG ARG A . n A 1 527 HIS 527 547 547 HIS HIS A . n A 1 528 ARG 528 548 548 ARG ARG A . n A 1 529 VAL 529 549 549 VAL VAL A . n A 1 530 VAL 530 550 550 VAL VAL A . n A 1 531 GLN 531 551 551 GLN GLN A . n A 1 532 PRO 532 552 552 PRO PRO A . n A 1 533 THR 533 553 553 THR THR A . n A 1 534 LEU 534 554 554 LEU LEU A . n A 1 535 GLU 535 555 555 GLU GLU A . n A 1 536 GLN 536 556 556 GLN GLN A . n A 1 537 THR 537 557 557 THR THR A . n A 1 538 GLN 538 558 558 GLN GLN A . n A 1 539 TYR 539 559 559 TYR TYR A . n A 1 540 SER 540 560 560 SER SER A . n A 1 541 TRP 541 561 561 TRP TRP A . n A 1 542 GLU 542 562 562 GLU GLU A . n A 1 543 ARG 543 563 563 ARG ARG A . n A 1 544 GLN 544 564 564 GLN GLN A . n A 1 545 ALA 545 565 565 ALA ALA A . n A 1 546 ALA 546 566 566 ALA ALA A . n A 1 547 PHE 547 567 567 PHE PHE A . n A 1 548 ARG 548 568 568 ARG ARG A . n A 1 549 PHE 549 569 569 PHE PHE A . n A 1 550 LYS 550 570 570 LYS LYS A . n A 1 551 ARG 551 571 571 ARG ARG A . n A 1 552 LYS 552 572 572 LYS LYS A . n A 1 553 LEU 553 573 573 LEU LEU A . n A 1 554 PRO 554 574 574 PRO PRO A . n A 1 555 LYS 555 575 575 LYS LYS A . n A 1 556 TYR 556 576 576 TYR TYR A . n A 1 557 LEU 557 577 577 LEU LEU A . n A 1 558 LEU 558 578 578 LEU LEU A . n A 1 559 PHE 559 579 579 PHE PHE A . n A 1 560 THR 560 580 580 THR THR A . n A 1 561 SER 561 581 581 SER SER A . n A 1 562 PRO 562 582 582 PRO PRO A . n A 1 563 GLN 563 583 583 GLN GLN A . n A 1 564 GLU 564 584 584 GLU GLU A . n A 1 565 ASN 565 585 585 ASN ASN A . n A 1 566 PRO 566 586 586 PRO PRO A . n A 1 567 TRP 567 587 587 TRP TRP A . n A 1 568 GLY 568 588 588 GLY GLY A . n A 1 569 HIS 569 589 589 HIS HIS A . n A 1 570 LYS 570 590 590 LYS LYS A . n A 1 571 ARG 571 591 591 ARG ARG A . n A 1 572 SER 572 592 592 SER SER A . n A 1 573 TYR 573 593 593 TYR TYR A . n A 1 574 ARG 574 594 594 ARG ARG A . n A 1 575 LEU 575 595 595 LEU LEU A . n A 1 576 GLN 576 596 596 GLN GLN A . n A 1 577 ILE 577 597 597 ILE ILE A . n A 1 578 HIS 578 598 598 HIS HIS A . n A 1 579 SER 579 599 599 SER SER A . n A 1 580 MET 580 600 600 MET MET A . n A 1 581 ALA 581 601 601 ALA ALA A . n A 1 582 ASP 582 602 602 ASP ASP A . n A 1 583 GLN 583 603 603 GLN GLN A . n A 1 584 VAL 584 604 604 VAL VAL A . n A 1 585 LEU 585 605 605 LEU LEU A . n A 1 586 PRO 586 606 606 PRO PRO A . n A 1 587 PRO 587 607 607 PRO PRO A . n A 1 588 GLY 588 608 608 GLY GLY A . n A 1 589 TRP 589 609 609 TRP TRP A . n A 1 590 GLN 590 610 610 GLN GLN A . n A 1 591 GLU 591 611 611 GLU GLU A . n A 1 592 GLU 592 612 612 GLU GLU A . n A 1 593 GLN 593 613 613 GLN GLN A . n A 1 594 ALA 594 614 614 ALA ALA A . n A 1 595 ILE 595 615 615 ILE ILE A . n A 1 596 THR 596 616 616 THR THR A . n A 1 597 TRP 597 617 617 TRP TRP A . n A 1 598 ALA 598 618 618 ALA ALA A . n A 1 599 ARG 599 619 619 ARG ARG A . n A 1 600 TYR 600 620 620 TYR TYR A . n A 1 601 PRO 601 621 621 PRO PRO A . n A 1 602 LEU 602 622 622 LEU LEU A . n A 1 603 ALA 603 623 623 ALA ALA A . n A 1 604 VAL 604 624 624 VAL VAL A . n A 1 605 THR 605 625 625 THR THR A . n A 1 606 LYS 606 626 626 LYS LYS A . n A 1 607 TYR 607 627 627 TYR TYR A . n A 1 608 ARG 608 628 628 ARG ARG A . n A 1 609 GLU 609 629 629 GLU GLU A . n A 1 610 SER 610 630 630 SER SER A . n A 1 611 GLU 611 631 631 GLU GLU A . n A 1 612 LEU 612 632 632 LEU LEU A . n A 1 613 CYS 613 633 633 CYS CYS A . n A 1 614 SER 614 634 634 SER SER A . n A 1 615 SER 615 635 635 SER SER A . n A 1 616 SER 616 636 636 SER SER A . n A 1 617 ILE 617 637 637 ILE ILE A . n A 1 618 TYR 618 638 638 TYR TYR A . n A 1 619 HIS 619 639 639 HIS HIS A . n A 1 620 GLN 620 640 640 GLN GLN A . n A 1 621 ASN 621 641 641 ASN ASN A . n A 1 622 ASP 622 642 642 ASP ASP A . n A 1 623 PRO 623 643 643 PRO PRO A . n A 1 624 TRP 624 644 644 TRP TRP A . n A 1 625 ASP 625 645 645 ASP ASP A . n A 1 626 PRO 626 646 646 PRO PRO A . n A 1 627 PRO 627 647 647 PRO PRO A . n A 1 628 VAL 628 648 648 VAL VAL A . n A 1 629 VAL 629 649 649 VAL VAL A . n A 1 630 PHE 630 650 650 PHE PHE A . n A 1 631 GLU 631 651 651 GLU GLU A . n A 1 632 GLN 632 652 652 GLN GLN A . n A 1 633 PHE 633 653 653 PHE PHE A . n A 1 634 LEU 634 654 654 LEU LEU A . n A 1 635 HIS 635 655 655 HIS HIS A . n A 1 636 ASN 636 656 656 ASN ASN A . n A 1 637 ASN 637 657 657 ASN ASN A . n A 1 638 GLU 638 658 658 GLU GLU A . n A 1 639 ASN 639 659 659 ASN ASN A . n A 1 640 ILE 640 660 660 ILE ILE A . n A 1 641 GLU 641 661 661 GLU GLU A . n A 1 642 ASN 642 662 662 ASN ASN A . n A 1 643 GLU 643 663 663 GLU GLU A . n A 1 644 ASP 644 664 664 ASP ASP A . n A 1 645 LEU 645 665 665 LEU LEU A . n A 1 646 VAL 646 666 666 VAL VAL A . n A 1 647 ALA 647 667 667 ALA ALA A . n A 1 648 TRP 648 668 668 TRP TRP A . n A 1 649 VAL 649 669 669 VAL VAL A . n A 1 650 THR 650 670 670 THR THR A . n A 1 651 VAL 651 671 671 VAL VAL A . n A 1 652 GLY 652 672 672 GLY GLY A . n A 1 653 PHE 653 673 673 PHE PHE A . n A 1 654 LEU 654 674 674 LEU LEU A . n A 1 655 HIS 655 675 675 HIS HIS A . n A 1 656 ILE 656 676 676 ILE ILE A . n A 1 657 PRO 657 677 677 PRO PRO A . n A 1 658 HIS 658 678 678 HIS HIS A . n A 1 659 SER 659 679 679 SER SER A . n A 1 660 GLU 660 680 680 GLU GLU A . n A 1 661 ASP 661 681 681 ASP ASP A . n A 1 662 ILE 662 682 682 ILE ILE A . n A 1 663 PRO 663 683 683 PRO PRO A . n A 1 664 ASN 664 684 684 ASN ASN A . n A 1 665 THR 665 685 685 THR THR A . n A 1 666 ALA 666 686 686 ALA ALA A . n A 1 667 THR 667 687 687 THR THR A . n A 1 668 PRO 668 688 688 PRO PRO A . n A 1 669 GLY 669 689 689 GLY GLY A . n A 1 670 ASN 670 690 690 ASN ASN A . n A 1 671 SER 671 691 691 SER SER A . n A 1 672 VAL 672 692 692 VAL VAL A . n A 1 673 GLY 673 693 693 GLY GLY A . n A 1 674 PHE 674 694 694 PHE PHE A . n A 1 675 LEU 675 695 695 LEU LEU A . n A 1 676 LEU 676 696 696 LEU LEU A . n A 1 677 ARG 677 697 697 ARG ARG A . n A 1 678 PRO 678 698 698 PRO PRO A . n A 1 679 PHE 679 699 699 PHE PHE A . n A 1 680 ASN 680 700 700 ASN ASN A . n A 1 681 PHE 681 701 701 PHE PHE A . n A 1 682 PHE 682 702 702 PHE PHE A . n A 1 683 PRO 683 703 703 PRO PRO A . n A 1 684 GLU 684 704 704 GLU GLU A . n A 1 685 ASP 685 705 705 ASP ASP A . n A 1 686 PRO 686 706 706 PRO PRO A . n A 1 687 SER 687 707 707 SER SER A . n A 1 688 LEU 688 708 708 LEU LEU A . n A 1 689 ALA 689 709 709 ALA ALA A . n A 1 690 SER 690 710 710 SER SER A . n A 1 691 ARG 691 711 711 ARG ARG A . n A 1 692 ASP 692 712 712 ASP ASP A . n A 1 693 THR 693 713 713 THR THR A . n A 1 694 VAL 694 714 714 VAL VAL A . n A 1 695 ILE 695 715 715 ILE ILE A . n A 1 696 VAL 696 716 716 VAL VAL A . n A 1 697 TRP 697 717 717 TRP TRP A . n A 1 698 PRO 698 718 718 PRO PRO A . n A 1 699 ARG 699 719 719 ARG ARG A . n A 1 700 ASP 700 720 720 ASP ASP A . n A 1 701 ASN 701 721 721 ASN ASN A . n A 1 702 GLY 702 722 722 GLY GLY A . n A 1 703 PRO 703 723 723 PRO PRO A . n A 1 704 ASN 704 724 724 ASN ASN A . n A 1 705 TYR 705 725 725 TYR TYR A . n A 1 706 VAL 706 726 726 VAL VAL A . n A 1 707 GLN 707 727 727 GLN GLN A . n A 1 708 ARG 708 728 728 ARG ARG A . n A 1 709 TRP 709 729 729 TRP TRP A . n A 1 710 ILE 710 730 730 ILE ILE A . n A 1 711 PRO 711 731 731 PRO PRO A . n A 1 712 GLU 712 732 732 GLU GLU A . n A 1 713 ASP 713 733 733 ASP ASP A . n A 1 714 ARG 714 734 734 ARG ARG A . n A 1 715 ASP 715 735 735 ASP ASP A . n A 1 716 CYS 716 736 736 CYS CYS A . n A 1 717 SER 717 737 737 SER SER A . n A 1 718 MET 718 738 738 MET MET A . n A 1 719 PRO 719 739 739 PRO PRO A . n A 1 720 PRO 720 740 740 PRO PRO A . n A 1 721 PRO 721 741 741 PRO PRO A . n A 1 722 PHE 722 742 742 PHE PHE A . n A 1 723 SER 723 743 743 SER SER A . n A 1 724 TYR 724 744 744 TYR TYR A . n A 1 725 ASN 725 745 745 ASN ASN A . n A 1 726 GLY 726 746 746 GLY GLY A . n A 1 727 THR 727 747 747 THR THR A . n A 1 728 TYR 728 748 748 TYR TYR A . n A 1 729 ARG 729 749 749 ARG ARG A . n A 1 730 PRO 730 750 750 PRO PRO A . n A 1 731 VAL 731 751 751 VAL VAL A . n B 1 1 ARG 1 21 ? ? ? B . n B 1 2 SER 2 22 ? ? ? B . n B 1 3 PRO 3 23 ? ? ? B . n B 1 4 GLY 4 24 ? ? ? B . n B 1 5 THR 5 25 ? ? ? B . n B 1 6 LEU 6 26 ? ? ? B . n B 1 7 PRO 7 27 ? ? ? B . n B 1 8 ARG 8 28 28 ARG ARG B . n B 1 9 LYS 9 29 29 LYS LYS B . n B 1 10 ALA 10 30 30 ALA ALA B . n B 1 11 GLY 11 31 31 GLY GLY B . n B 1 12 VAL 12 32 32 VAL VAL B . n B 1 13 PHE 13 33 33 PHE PHE B . n B 1 14 SER 14 34 34 SER SER B . n B 1 15 ASP 15 35 35 ASP ASP B . n B 1 16 LEU 16 36 36 LEU LEU B . n B 1 17 SER 17 37 37 SER SER B . n B 1 18 ASN 18 38 38 ASN ASN B . n B 1 19 GLN 19 39 39 GLN GLN B . n B 1 20 GLU 20 40 40 GLU GLU B . n B 1 21 LEU 21 41 41 LEU LEU B . n B 1 22 LYS 22 42 42 LYS LYS B . n B 1 23 ALA 23 43 43 ALA ALA B . n B 1 24 VAL 24 44 44 VAL VAL B . n B 1 25 HIS 25 45 45 HIS HIS B . n B 1 26 SER 26 46 46 SER SER B . n B 1 27 PHE 27 47 47 PHE PHE B . n B 1 28 LEU 28 48 48 LEU LEU B . n B 1 29 TRP 29 49 49 TRP TRP B . n B 1 30 SER 30 50 50 SER SER B . n B 1 31 LYS 31 51 51 LYS LYS B . n B 1 32 LYS 32 52 52 LYS LYS B . n B 1 33 GLU 33 53 53 GLU GLU B . n B 1 34 LEU 34 54 54 LEU LEU B . n B 1 35 ARG 35 55 55 ARG ARG B . n B 1 36 LEU 36 56 56 LEU LEU B . n B 1 37 GLN 37 57 57 GLN GLN B . n B 1 38 PRO 38 58 58 PRO PRO B . n B 1 39 SER 39 59 59 SER SER B . n B 1 40 SER 40 60 60 SER SER B . n B 1 41 THR 41 61 61 THR THR B . n B 1 42 THR 42 62 62 THR THR B . n B 1 43 THR 43 63 63 THR THR B . n B 1 44 MET 44 64 64 MET MET B . n B 1 45 ALA 45 65 65 ALA ALA B . n B 1 46 LYS 46 66 66 LYS LYS B . n B 1 47 ASN 47 67 67 ASN ASN B . n B 1 48 THR 48 68 68 THR THR B . n B 1 49 VAL 49 69 69 VAL VAL B . n B 1 50 PHE 50 70 70 PHE PHE B . n B 1 51 LEU 51 71 71 LEU LEU B . n B 1 52 ILE 52 72 72 ILE ILE B . n B 1 53 GLU 53 73 73 GLU GLU B . n B 1 54 MET 54 74 74 MET MET B . n B 1 55 LEU 55 75 75 LEU LEU B . n B 1 56 LEU 56 76 76 LEU LEU B . n B 1 57 PRO 57 77 77 PRO PRO B . n B 1 58 LYS 58 78 78 LYS LYS B . n B 1 59 LYS 59 79 79 LYS LYS B . n B 1 60 TYR 60 80 80 TYR TYR B . n B 1 61 HIS 61 81 81 HIS HIS B . n B 1 62 VAL 62 82 82 VAL VAL B . n B 1 63 LEU 63 83 83 LEU LEU B . n B 1 64 ARG 64 84 84 ARG ARG B . n B 1 65 PHE 65 85 85 PHE PHE B . n B 1 66 LEU 66 86 86 LEU LEU B . n B 1 67 ASP 67 87 87 ASP ASP B . n B 1 68 LYS 68 88 88 LYS LYS B . n B 1 69 GLY 69 89 89 GLY GLY B . n B 1 70 GLU 70 90 90 GLU GLU B . n B 1 71 ARG 71 91 91 ARG ARG B . n B 1 72 HIS 72 92 92 HIS HIS B . n B 1 73 PRO 73 93 93 PRO PRO B . n B 1 74 VAL 74 94 94 VAL VAL B . n B 1 75 ARG 75 95 95 ARG ARG B . n B 1 76 GLU 76 96 96 GLU GLU B . n B 1 77 ALA 77 97 97 ALA ALA B . n B 1 78 ARG 78 98 98 ARG ARG B . n B 1 79 ALA 79 99 99 ALA ALA B . n B 1 80 VAL 80 100 100 VAL VAL B . n B 1 81 ILE 81 101 101 ILE ILE B . n B 1 82 PHE 82 102 102 PHE PHE B . n B 1 83 PHE 83 103 103 PHE PHE B . n B 1 84 GLY 84 104 104 GLY GLY B . n B 1 85 ASP 85 105 105 ASP ASP B . n B 1 86 GLN 86 106 106 GLN GLN B . n B 1 87 GLU 87 107 107 GLU GLU B . n B 1 88 HIS 88 108 108 HIS HIS B . n B 1 89 PRO 89 109 109 PRO PRO B . n B 1 90 ASN 90 110 110 ASN ASN B . n B 1 91 VAL 91 111 111 VAL VAL B . n B 1 92 THR 92 112 112 THR THR B . n B 1 93 GLU 93 113 113 GLU GLU B . n B 1 94 PHE 94 114 114 PHE PHE B . n B 1 95 ALA 95 115 115 ALA ALA B . n B 1 96 VAL 96 116 116 VAL VAL B . n B 1 97 GLY 97 117 117 GLY GLY B . n B 1 98 PRO 98 118 118 PRO PRO B . n B 1 99 LEU 99 119 119 LEU LEU B . n B 1 100 PRO 100 120 120 PRO PRO B . n B 1 101 GLY 101 121 121 GLY GLY B . n B 1 102 PRO 102 122 122 PRO PRO B . n B 1 103 CYS 103 123 123 CYS CYS B . n B 1 104 TYR 104 124 124 TYR TYR B . n B 1 105 MET 105 125 125 MET MET B . n B 1 106 ARG 106 126 126 ARG ARG B . n B 1 107 ALA 107 127 127 ALA ALA B . n B 1 108 LEU 108 128 128 LEU LEU B . n B 1 109 SER 109 129 129 SER SER B . n B 1 110 PRO 110 130 130 PRO PRO B . n B 1 111 ARG 111 131 131 ARG ARG B . n B 1 112 PRO 112 132 132 PRO PRO B . n B 1 113 GLY 113 133 133 GLY GLY B . n B 1 114 TYR 114 134 134 TYR TYR B . n B 1 115 GLN 115 135 135 GLN GLN B . n B 1 116 SER 116 136 136 SER SER B . n B 1 117 SER 117 137 137 SER SER B . n B 1 118 TRP 118 138 138 TRP TRP B . n B 1 119 ALA 119 139 139 ALA ALA B . n B 1 120 SER 120 140 140 SER SER B . n B 1 121 ARG 121 141 141 ARG ARG B . n B 1 122 PRO 122 142 142 PRO PRO B . n B 1 123 ILE 123 143 143 ILE ILE B . n B 1 124 SER 124 144 144 SER SER B . n B 1 125 THR 125 145 145 THR THR B . n B 1 126 ALA 126 146 146 ALA ALA B . n B 1 127 GLU 127 147 147 GLU GLU B . n B 1 128 TYR 128 148 148 TYR TYR B . n B 1 129 ALA 129 149 149 ALA ALA B . n B 1 130 LEU 130 150 150 LEU LEU B . n B 1 131 LEU 131 151 151 LEU LEU B . n B 1 132 TYR 132 152 152 TYR TYR B . n B 1 133 HIS 133 153 153 HIS HIS B . n B 1 134 THR 134 154 154 THR THR B . n B 1 135 LEU 135 155 155 LEU LEU B . n B 1 136 GLN 136 156 156 GLN GLN B . n B 1 137 GLU 137 157 157 GLU GLU B . n B 1 138 ALA 138 158 158 ALA ALA B . n B 1 139 THR 139 159 159 THR THR B . n B 1 140 LYS 140 160 160 LYS LYS B . n B 1 141 PRO 141 161 161 PRO PRO B . n B 1 142 LEU 142 162 162 LEU LEU B . n B 1 143 HIS 143 163 163 HIS HIS B . n B 1 144 GLN 144 164 164 GLN GLN B . n B 1 145 PHE 145 165 165 PHE PHE B . n B 1 146 PHE 146 166 166 PHE PHE B . n B 1 147 LEU 147 167 167 LEU LEU B . n B 1 148 ASN 148 168 168 ASN ASN B . n B 1 149 THR 149 169 169 THR THR B . n B 1 150 THR 150 170 170 THR THR B . n B 1 151 GLY 151 171 171 GLY GLY B . n B 1 152 PHE 152 172 172 PHE PHE B . n B 1 153 SER 153 173 173 SER SER B . n B 1 154 PHE 154 174 174 PHE PHE B . n B 1 155 GLN 155 175 175 GLN GLN B . n B 1 156 ASP 156 176 176 ASP ASP B . n B 1 157 CYS 157 177 177 CYS CYS B . n B 1 158 HIS 158 178 178 HIS HIS B . n B 1 159 ASP 159 179 179 ASP ASP B . n B 1 160 ARG 160 180 180 ARG ARG B . n B 1 161 CYS 161 181 181 CYS CYS B . n B 1 162 LEU 162 182 182 LEU LEU B . n B 1 163 ALA 163 183 183 ALA ALA B . n B 1 164 PHE 164 184 184 PHE PHE B . n B 1 165 THR 165 185 185 THR THR B . n B 1 166 ASP 166 186 186 ASP ASP B . n B 1 167 VAL 167 187 187 VAL VAL B . n B 1 168 ALA 168 188 188 ALA ALA B . n B 1 169 PRO 169 189 189 PRO PRO B . n B 1 170 ARG 170 190 190 ARG ARG B . n B 1 171 GLY 171 191 191 GLY GLY B . n B 1 172 VAL 172 192 192 VAL VAL B . n B 1 173 ALA 173 193 193 ALA ALA B . n B 1 174 SER 174 194 194 SER SER B . n B 1 175 GLY 175 195 195 GLY GLY B . n B 1 176 GLN 176 196 196 GLN GLN B . n B 1 177 ARG 177 197 197 ARG ARG B . n B 1 178 ARG 178 198 198 ARG ARG B . n B 1 179 SER 179 199 199 SER SER B . n B 1 180 TRP 180 200 200 TRP TRP B . n B 1 181 LEU 181 201 201 LEU LEU B . n B 1 182 ILE 182 202 202 ILE ILE B . n B 1 183 ILE 183 203 203 ILE ILE B . n B 1 184 GLN 184 204 204 GLN GLN B . n B 1 185 ARG 185 205 205 ARG ARG B . n B 1 186 TYR 186 206 206 TYR TYR B . n B 1 187 VAL 187 207 207 VAL VAL B . n B 1 188 GLU 188 208 208 GLU GLU B . n B 1 189 GLY 189 209 209 GLY GLY B . n B 1 190 TYR 190 210 210 TYR TYR B . n B 1 191 PHE 191 211 211 PHE PHE B . n B 1 192 LEU 192 212 212 LEU LEU B . n B 1 193 HIS 193 213 213 HIS HIS B . n B 1 194 PRO 194 214 214 PRO PRO B . n B 1 195 THR 195 215 215 THR THR B . n B 1 196 GLY 196 216 216 GLY GLY B . n B 1 197 LEU 197 217 217 LEU LEU B . n B 1 198 GLU 198 218 218 GLU GLU B . n B 1 199 LEU 199 219 219 LEU LEU B . n B 1 200 LEU 200 220 220 LEU LEU B . n B 1 201 VAL 201 221 221 VAL VAL B . n B 1 202 ASP 202 222 222 ASP ASP B . n B 1 203 HIS 203 223 223 HIS HIS B . n B 1 204 GLY 204 224 224 GLY GLY B . n B 1 205 SER 205 225 225 SER SER B . n B 1 206 THR 206 226 226 THR THR B . n B 1 207 ASP 207 227 227 ASP ASP B . n B 1 208 ALA 208 228 228 ALA ALA B . n B 1 209 GLY 209 229 229 GLY GLY B . n B 1 210 HIS 210 230 230 HIS HIS B . n B 1 211 TRP 211 231 231 TRP TRP B . n B 1 212 ALA 212 232 232 ALA ALA B . n B 1 213 VAL 213 233 233 VAL VAL B . n B 1 214 GLU 214 234 234 GLU GLU B . n B 1 215 GLN 215 235 235 GLN GLN B . n B 1 216 VAL 216 236 236 VAL VAL B . n B 1 217 TRP 217 237 237 TRP TRP B . n B 1 218 TYR 218 238 238 TYR TYR B . n B 1 219 ASN 219 239 239 ASN ASN B . n B 1 220 GLY 220 240 240 GLY GLY B . n B 1 221 LYS 221 241 241 LYS LYS B . n B 1 222 PHE 222 242 242 PHE PHE B . n B 1 223 TYR 223 243 243 TYR TYR B . n B 1 224 GLY 224 244 244 GLY GLY B . n B 1 225 SER 225 245 245 SER SER B . n B 1 226 PRO 226 246 246 PRO PRO B . n B 1 227 GLU 227 247 247 GLU GLU B . n B 1 228 GLU 228 248 248 GLU GLU B . n B 1 229 LEU 229 249 249 LEU LEU B . n B 1 230 ALA 230 250 250 ALA ALA B . n B 1 231 ARG 231 251 251 ARG ARG B . n B 1 232 LYS 232 252 252 LYS LYS B . n B 1 233 TYR 233 253 253 TYR TYR B . n B 1 234 ALA 234 254 254 ALA ALA B . n B 1 235 ASP 235 255 255 ASP ASP B . n B 1 236 GLY 236 256 256 GLY GLY B . n B 1 237 GLU 237 257 257 GLU GLU B . n B 1 238 VAL 238 258 258 VAL VAL B . n B 1 239 ASP 239 259 259 ASP ASP B . n B 1 240 VAL 240 260 260 VAL VAL B . n B 1 241 VAL 241 261 261 VAL VAL B . n B 1 242 VAL 242 262 262 VAL VAL B . n B 1 243 LEU 243 263 263 LEU LEU B . n B 1 244 GLU 244 264 ? ? ? B . n B 1 245 ASP 245 265 ? ? ? B . n B 1 246 PRO 246 266 ? ? ? B . n B 1 247 LEU 247 267 ? ? ? B . n B 1 248 PRO 248 268 ? ? ? B . n B 1 249 GLY 249 269 ? ? ? B . n B 1 250 GLY 250 270 ? ? ? B . n B 1 251 LYS 251 271 ? ? ? B . n B 1 252 GLY 252 272 ? ? ? B . n B 1 253 HIS 253 273 ? ? ? B . n B 1 254 ASP 254 274 ? ? ? B . n B 1 255 SER 255 275 ? ? ? B . n B 1 256 THR 256 276 ? ? ? B . n B 1 257 GLU 257 277 ? ? ? B . n B 1 258 GLU 258 278 278 GLU GLU B . n B 1 259 PRO 259 279 279 PRO PRO B . n B 1 260 PRO 260 280 280 PRO PRO B . n B 1 261 LEU 261 281 281 LEU LEU B . n B 1 262 PHE 262 282 282 PHE PHE B . n B 1 263 SER 263 283 283 SER SER B . n B 1 264 SER 264 284 284 SER SER B . n B 1 265 HIS 265 285 285 HIS HIS B . n B 1 266 LYS 266 286 286 LYS LYS B . n B 1 267 PRO 267 287 287 PRO PRO B . n B 1 268 ARG 268 288 288 ARG ARG B . n B 1 269 GLY 269 289 289 GLY GLY B . n B 1 270 ASP 270 290 290 ASP ASP B . n B 1 271 PHE 271 291 291 PHE PHE B . n B 1 272 PRO 272 292 292 PRO PRO B . n B 1 273 SER 273 293 293 SER SER B . n B 1 274 PRO 274 294 294 PRO PRO B . n B 1 275 ILE 275 295 295 ILE ILE B . n B 1 276 HIS 276 296 296 HIS HIS B . n B 1 277 VAL 277 297 297 VAL VAL B . n B 1 278 SER 278 298 298 SER SER B . n B 1 279 GLY 279 299 299 GLY GLY B . n B 1 280 PRO 280 300 300 PRO PRO B . n B 1 281 ARG 281 301 301 ARG ARG B . n B 1 282 LEU 282 302 302 LEU LEU B . n B 1 283 VAL 283 303 303 VAL VAL B . n B 1 284 GLN 284 304 304 GLN GLN B . n B 1 285 PRO 285 305 305 PRO PRO B . n B 1 286 HIS 286 306 306 HIS HIS B . n B 1 287 GLY 287 307 307 GLY GLY B . n B 1 288 PRO 288 308 308 PRO PRO B . n B 1 289 ARG 289 309 309 ARG ARG B . n B 1 290 PHE 290 310 310 PHE PHE B . n B 1 291 ARG 291 311 311 ARG ARG B . n B 1 292 LEU 292 312 312 LEU LEU B . n B 1 293 GLU 293 313 313 GLU GLU B . n B 1 294 GLY 294 314 314 GLY GLY B . n B 1 295 ASN 295 315 315 ASN ASN B . n B 1 296 ALA 296 316 316 ALA ALA B . n B 1 297 VAL 297 317 317 VAL VAL B . n B 1 298 LEU 298 318 318 LEU LEU B . n B 1 299 TYR 299 319 319 TYR TYR B . n B 1 300 GLY 300 320 320 GLY GLY B . n B 1 301 GLY 301 321 321 GLY GLY B . n B 1 302 TRP 302 322 322 TRP TRP B . n B 1 303 SER 303 323 323 SER SER B . n B 1 304 PHE 304 324 324 PHE PHE B . n B 1 305 ALA 305 325 325 ALA ALA B . n B 1 306 PHE 306 326 326 PHE PHE B . n B 1 307 ARG 307 327 327 ARG ARG B . n B 1 308 LEU 308 328 328 LEU LEU B . n B 1 309 ARG 309 329 329 ARG ARG B . n B 1 310 SER 310 330 330 SER SER B . n B 1 311 SER 311 331 331 SER SER B . n B 1 312 SER 312 332 332 SER SER B . n B 1 313 GLY 313 333 333 GLY GLY B . n B 1 314 LEU 314 334 334 LEU LEU B . n B 1 315 GLN 315 335 335 GLN GLN B . n B 1 316 VAL 316 336 336 VAL VAL B . n B 1 317 LEU 317 337 337 LEU LEU B . n B 1 318 ASN 318 338 338 ASN ASN B . n B 1 319 VAL 319 339 339 VAL VAL B . n B 1 320 HIS 320 340 340 HIS HIS B . n B 1 321 PHE 321 341 341 PHE PHE B . n B 1 322 GLY 322 342 342 GLY GLY B . n B 1 323 GLY 323 343 343 GLY GLY B . n B 1 324 GLU 324 344 344 GLU GLU B . n B 1 325 ARG 325 345 345 ARG ARG B . n B 1 326 ILE 326 346 346 ILE ILE B . n B 1 327 ALA 327 347 347 ALA ALA B . n B 1 328 TYR 328 348 348 TYR TYR B . n B 1 329 GLU 329 349 349 GLU GLU B . n B 1 330 VAL 330 350 350 VAL VAL B . n B 1 331 SER 331 351 351 SER SER B . n B 1 332 VAL 332 352 352 VAL VAL B . n B 1 333 GLN 333 353 353 GLN GLN B . n B 1 334 GLU 334 354 354 GLU GLU B . n B 1 335 ALA 335 355 355 ALA ALA B . n B 1 336 VAL 336 356 356 VAL VAL B . n B 1 337 ALA 337 357 357 ALA ALA B . n B 1 338 LEU 338 358 358 LEU LEU B . n B 1 339 TYR 339 359 359 TYR TYR B . n B 1 340 GLY 340 360 360 GLY GLY B . n B 1 341 GLY 341 361 361 GLY GLY B . n B 1 342 HIS 342 362 362 HIS HIS B . n B 1 343 THR 343 363 363 THR THR B . n B 1 344 PRO 344 364 364 PRO PRO B . n B 1 345 ALA 345 365 365 ALA ALA B . n B 1 346 GLY 346 366 366 GLY GLY B . n B 1 347 MET 347 367 367 MET MET B . n B 1 348 GLN 348 368 368 GLN GLN B . n B 1 349 THR 349 369 369 THR THR B . n B 1 350 LYS 350 370 370 LYS LYS B . n B 1 351 TYR 351 371 371 TYR TYR B . n B 1 352 LEU 352 372 372 LEU LEU B . n B 1 353 ASP 353 373 373 ASP ASP B . n B 1 354 VAL 354 374 374 VAL VAL B . n B 1 355 GLY 355 375 375 GLY GLY B . n B 1 356 TRP 356 376 376 TRP TRP B . n B 1 357 GLY 357 377 377 GLY GLY B . n B 1 358 LEU 358 378 378 LEU LEU B . n B 1 359 GLY 359 379 379 GLY GLY B . n B 1 360 SER 360 380 380 SER SER B . n B 1 361 VAL 361 381 381 VAL VAL B . n B 1 362 THR 362 382 382 THR THR B . n B 1 363 HIS 363 383 383 HIS HIS B . n B 1 364 GLU 364 384 384 GLU GLU B . n B 1 365 LEU 365 385 385 LEU LEU B . n B 1 366 ALA 366 386 386 ALA ALA B . n B 1 367 PRO 367 387 387 PRO PRO B . n B 1 368 GLY 368 388 388 GLY GLY B . n B 1 369 ILE 369 389 389 ILE ILE B . n B 1 370 ASP 370 390 390 ASP ASP B . n B 1 371 CYS 371 391 391 CYS CYS B . n B 1 372 PRO 372 392 392 PRO PRO B . n B 1 373 GLU 373 393 393 GLU GLU B . n B 1 374 THR 374 394 394 THR THR B . n B 1 375 ALA 375 395 395 ALA ALA B . n B 1 376 THR 376 396 396 THR THR B . n B 1 377 PHE 377 397 397 PHE PHE B . n B 1 378 LEU 378 398 398 LEU LEU B . n B 1 379 ASP 379 399 399 ASP ASP B . n B 1 380 THR 380 400 400 THR THR B . n B 1 381 PHE 381 401 401 PHE PHE B . n B 1 382 HIS 382 402 402 HIS HIS B . n B 1 383 TYR 383 403 403 TYR TYR B . n B 1 384 TYR 384 404 404 TYR TYR B . n B 1 385 ASP 385 405 405 ASP ASP B . n B 1 386 ALA 386 406 406 ALA ALA B . n B 1 387 ASP 387 407 407 ASP ASP B . n B 1 388 ASP 388 408 408 ASP ASP B . n B 1 389 PRO 389 409 409 PRO PRO B . n B 1 390 VAL 390 410 410 VAL VAL B . n B 1 391 HIS 391 411 411 HIS HIS B . n B 1 392 TYR 392 412 412 TYR TYR B . n B 1 393 PRO 393 413 413 PRO PRO B . n B 1 394 ARG 394 414 414 ARG ARG B . n B 1 395 ALA 395 415 415 ALA ALA B . n B 1 396 LEU 396 416 416 LEU LEU B . n B 1 397 CYS 397 417 417 CYS CYS B . n B 1 398 LEU 398 418 418 LEU LEU B . n B 1 399 PHE 399 419 419 PHE PHE B . n B 1 400 GLU 400 420 420 GLU GLU B . n B 1 401 MET 401 421 421 MET MET B . n B 1 402 PRO 402 422 422 PRO PRO B . n B 1 403 THR 403 423 423 THR THR B . n B 1 404 GLY 404 424 424 GLY GLY B . n B 1 405 VAL 405 425 425 VAL VAL B . n B 1 406 PRO 406 426 426 PRO PRO B . n B 1 407 LEU 407 427 427 LEU LEU B . n B 1 408 ARG 408 428 428 ARG ARG B . n B 1 409 ARG 409 429 429 ARG ARG B . n B 1 410 HIS 410 430 430 HIS HIS B . n B 1 411 PHE 411 431 431 PHE PHE B . n B 1 412 ASN 412 432 432 ASN ASN B . n B 1 413 SER 413 433 433 SER SER B . n B 1 414 ASN 414 434 434 ASN ASN B . n B 1 415 PHE 415 435 435 PHE PHE B . n B 1 416 LYS 416 436 436 LYS LYS B . n B 1 417 GLY 417 437 437 GLY GLY B . n B 1 418 GLY 418 438 438 GLY GLY B . n B 1 419 PHE 419 439 439 PHE PHE B . n B 1 420 ASN 420 440 440 ASN ASN B . n B 1 421 PHE 421 441 441 PHE PHE B . n B 1 422 TYR 422 442 442 TYR TYR B . n B 1 423 ALA 423 443 443 ALA ALA B . n B 1 424 GLY 424 444 444 GLY GLY B . n B 1 425 LEU 425 445 445 LEU LEU B . n B 1 426 LYS 426 446 446 LYS LYS B . n B 1 427 GLY 427 447 447 GLY GLY B . n B 1 428 GLN 428 448 448 GLN GLN B . n B 1 429 VAL 429 449 449 VAL VAL B . n B 1 430 LEU 430 450 450 LEU LEU B . n B 1 431 VAL 431 451 451 VAL VAL B . n B 1 432 LEU 432 452 452 LEU LEU B . n B 1 433 ARG 433 453 453 ARG ARG B . n B 1 434 THR 434 454 454 THR THR B . n B 1 435 THR 435 455 455 THR THR B . n B 1 436 SER 436 456 456 SER SER B . n B 1 437 THR 437 457 457 THR THR B . n B 1 438 VAL 438 458 458 VAL VAL B . n B 1 439 TYR 439 459 459 TYR TYR B . n B 1 440 ASN 440 460 460 ASN ASN B . n B 1 441 TPQ 441 461 461 TPQ TPQ B . n B 1 442 ASP 442 462 462 ASP ASP B . n B 1 443 TYR 443 463 463 TYR TYR B . n B 1 444 ILE 444 464 464 ILE ILE B . n B 1 445 TRP 445 465 465 TRP TRP B . n B 1 446 ASP 446 466 466 ASP ASP B . n B 1 447 PHE 447 467 467 PHE PHE B . n B 1 448 ILE 448 468 468 ILE ILE B . n B 1 449 PHE 449 469 469 PHE PHE B . n B 1 450 TYR 450 470 470 TYR TYR B . n B 1 451 PRO 451 471 471 PRO PRO B . n B 1 452 ASN 452 472 472 ASN ASN B . n B 1 453 GLY 453 473 473 GLY GLY B . n B 1 454 VAL 454 474 474 VAL VAL B . n B 1 455 MET 455 475 475 MET MET B . n B 1 456 GLU 456 476 476 GLU GLU B . n B 1 457 ALA 457 477 477 ALA ALA B . n B 1 458 LYS 458 478 478 LYS LYS B . n B 1 459 MET 459 479 479 MET MET B . n B 1 460 HIS 460 480 480 HIS HIS B . n B 1 461 ALA 461 481 481 ALA ALA B . n B 1 462 THR 462 482 482 THR THR B . n B 1 463 GLY 463 483 483 GLY GLY B . n B 1 464 TYR 464 484 484 TYR TYR B . n B 1 465 VAL 465 485 485 VAL VAL B . n B 1 466 HIS 466 486 486 HIS HIS B . n B 1 467 ALA 467 487 487 ALA ALA B . n B 1 468 THR 468 488 488 THR THR B . n B 1 469 PHE 469 489 489 PHE PHE B . n B 1 470 TYR 470 490 490 TYR TYR B . n B 1 471 THR 471 491 491 THR THR B . n B 1 472 PRO 472 492 492 PRO PRO B . n B 1 473 GLU 473 493 493 GLU GLU B . n B 1 474 GLY 474 494 494 GLY GLY B . n B 1 475 LEU 475 495 495 LEU LEU B . n B 1 476 ARG 476 496 496 ARG ARG B . n B 1 477 HIS 477 497 497 HIS HIS B . n B 1 478 GLY 478 498 498 GLY GLY B . n B 1 479 THR 479 499 499 THR THR B . n B 1 480 ARG 480 500 500 ARG ARG B . n B 1 481 LEU 481 501 501 LEU LEU B . n B 1 482 HIS 482 502 502 HIS HIS B . n B 1 483 THR 483 503 503 THR THR B . n B 1 484 HIS 484 504 504 HIS HIS B . n B 1 485 LEU 485 505 505 LEU LEU B . n B 1 486 ILE 486 506 506 ILE ILE B . n B 1 487 GLY 487 507 507 GLY GLY B . n B 1 488 ASN 488 508 508 ASN ASN B . n B 1 489 ILE 489 509 509 ILE ILE B . n B 1 490 HIS 490 510 510 HIS HIS B . n B 1 491 THR 491 511 511 THR THR B . n B 1 492 HIS 492 512 512 HIS HIS B . n B 1 493 LEU 493 513 513 LEU LEU B . n B 1 494 VAL 494 514 514 VAL VAL B . n B 1 495 HIS 495 515 515 HIS HIS B . n B 1 496 TYR 496 516 516 TYR TYR B . n B 1 497 ARG 497 517 517 ARG ARG B . n B 1 498 VAL 498 518 518 VAL VAL B . n B 1 499 ASP 499 519 519 ASP ASP B . n B 1 500 LEU 500 520 520 LEU LEU B . n B 1 501 ASP 501 521 521 ASP ASP B . n B 1 502 VAL 502 522 522 VAL VAL B . n B 1 503 ALA 503 523 523 ALA ALA B . n B 1 504 GLY 504 524 524 GLY GLY B . n B 1 505 THR 505 525 525 THR THR B . n B 1 506 LYS 506 526 526 LYS LYS B . n B 1 507 ASN 507 527 527 ASN ASN B . n B 1 508 SER 508 528 528 SER SER B . n B 1 509 PHE 509 529 529 PHE PHE B . n B 1 510 GLN 510 530 530 GLN GLN B . n B 1 511 THR 511 531 531 THR THR B . n B 1 512 LEU 512 532 532 LEU LEU B . n B 1 513 GLN 513 533 533 GLN GLN B . n B 1 514 MET 514 534 534 MET MET B . n B 1 515 LYS 515 535 535 LYS LYS B . n B 1 516 LEU 516 536 536 LEU LEU B . n B 1 517 GLU 517 537 537 GLU GLU B . n B 1 518 ASN 518 538 538 ASN ASN B . n B 1 519 ILE 519 539 539 ILE ILE B . n B 1 520 THR 520 540 540 THR THR B . n B 1 521 ASN 521 541 541 ASN ASN B . n B 1 522 PRO 522 542 542 PRO PRO B . n B 1 523 TRP 523 543 543 TRP TRP B . n B 1 524 SER 524 544 544 SER SER B . n B 1 525 PRO 525 545 545 PRO PRO B . n B 1 526 ARG 526 546 546 ARG ARG B . n B 1 527 HIS 527 547 547 HIS HIS B . n B 1 528 ARG 528 548 548 ARG ARG B . n B 1 529 VAL 529 549 549 VAL VAL B . n B 1 530 VAL 530 550 550 VAL VAL B . n B 1 531 GLN 531 551 551 GLN GLN B . n B 1 532 PRO 532 552 552 PRO PRO B . n B 1 533 THR 533 553 553 THR THR B . n B 1 534 LEU 534 554 554 LEU LEU B . n B 1 535 GLU 535 555 555 GLU GLU B . n B 1 536 GLN 536 556 556 GLN GLN B . n B 1 537 THR 537 557 557 THR THR B . n B 1 538 GLN 538 558 558 GLN GLN B . n B 1 539 TYR 539 559 559 TYR TYR B . n B 1 540 SER 540 560 560 SER SER B . n B 1 541 TRP 541 561 561 TRP TRP B . n B 1 542 GLU 542 562 562 GLU GLU B . n B 1 543 ARG 543 563 563 ARG ARG B . n B 1 544 GLN 544 564 564 GLN GLN B . n B 1 545 ALA 545 565 565 ALA ALA B . n B 1 546 ALA 546 566 566 ALA ALA B . n B 1 547 PHE 547 567 567 PHE PHE B . n B 1 548 ARG 548 568 568 ARG ARG B . n B 1 549 PHE 549 569 569 PHE PHE B . n B 1 550 LYS 550 570 570 LYS LYS B . n B 1 551 ARG 551 571 571 ARG ARG B . n B 1 552 LYS 552 572 572 LYS LYS B . n B 1 553 LEU 553 573 573 LEU LEU B . n B 1 554 PRO 554 574 574 PRO PRO B . n B 1 555 LYS 555 575 575 LYS LYS B . n B 1 556 TYR 556 576 576 TYR TYR B . n B 1 557 LEU 557 577 577 LEU LEU B . n B 1 558 LEU 558 578 578 LEU LEU B . n B 1 559 PHE 559 579 579 PHE PHE B . n B 1 560 THR 560 580 580 THR THR B . n B 1 561 SER 561 581 581 SER SER B . n B 1 562 PRO 562 582 582 PRO PRO B . n B 1 563 GLN 563 583 583 GLN GLN B . n B 1 564 GLU 564 584 584 GLU GLU B . n B 1 565 ASN 565 585 585 ASN ASN B . n B 1 566 PRO 566 586 586 PRO PRO B . n B 1 567 TRP 567 587 587 TRP TRP B . n B 1 568 GLY 568 588 588 GLY GLY B . n B 1 569 HIS 569 589 589 HIS HIS B . n B 1 570 LYS 570 590 590 LYS LYS B . n B 1 571 ARG 571 591 591 ARG ARG B . n B 1 572 SER 572 592 592 SER SER B . n B 1 573 TYR 573 593 593 TYR TYR B . n B 1 574 ARG 574 594 594 ARG ARG B . n B 1 575 LEU 575 595 595 LEU LEU B . n B 1 576 GLN 576 596 596 GLN GLN B . n B 1 577 ILE 577 597 597 ILE ILE B . n B 1 578 HIS 578 598 598 HIS HIS B . n B 1 579 SER 579 599 599 SER SER B . n B 1 580 MET 580 600 600 MET MET B . n B 1 581 ALA 581 601 601 ALA ALA B . n B 1 582 ASP 582 602 602 ASP ASP B . n B 1 583 GLN 583 603 603 GLN GLN B . n B 1 584 VAL 584 604 604 VAL VAL B . n B 1 585 LEU 585 605 605 LEU LEU B . n B 1 586 PRO 586 606 606 PRO PRO B . n B 1 587 PRO 587 607 607 PRO PRO B . n B 1 588 GLY 588 608 608 GLY GLY B . n B 1 589 TRP 589 609 609 TRP TRP B . n B 1 590 GLN 590 610 610 GLN GLN B . n B 1 591 GLU 591 611 611 GLU GLU B . n B 1 592 GLU 592 612 612 GLU GLU B . n B 1 593 GLN 593 613 613 GLN GLN B . n B 1 594 ALA 594 614 614 ALA ALA B . n B 1 595 ILE 595 615 615 ILE ILE B . n B 1 596 THR 596 616 616 THR THR B . n B 1 597 TRP 597 617 617 TRP TRP B . n B 1 598 ALA 598 618 618 ALA ALA B . n B 1 599 ARG 599 619 619 ARG ARG B . n B 1 600 TYR 600 620 620 TYR TYR B . n B 1 601 PRO 601 621 621 PRO PRO B . n B 1 602 LEU 602 622 622 LEU LEU B . n B 1 603 ALA 603 623 623 ALA ALA B . n B 1 604 VAL 604 624 624 VAL VAL B . n B 1 605 THR 605 625 625 THR THR B . n B 1 606 LYS 606 626 626 LYS LYS B . n B 1 607 TYR 607 627 627 TYR TYR B . n B 1 608 ARG 608 628 628 ARG ARG B . n B 1 609 GLU 609 629 629 GLU GLU B . n B 1 610 SER 610 630 630 SER SER B . n B 1 611 GLU 611 631 631 GLU GLU B . n B 1 612 LEU 612 632 632 LEU LEU B . n B 1 613 CYS 613 633 633 CYS CYS B . n B 1 614 SER 614 634 634 SER SER B . n B 1 615 SER 615 635 635 SER SER B . n B 1 616 SER 616 636 636 SER SER B . n B 1 617 ILE 617 637 637 ILE ILE B . n B 1 618 TYR 618 638 638 TYR TYR B . n B 1 619 HIS 619 639 639 HIS HIS B . n B 1 620 GLN 620 640 640 GLN GLN B . n B 1 621 ASN 621 641 641 ASN ASN B . n B 1 622 ASP 622 642 642 ASP ASP B . n B 1 623 PRO 623 643 643 PRO PRO B . n B 1 624 TRP 624 644 644 TRP TRP B . n B 1 625 ASP 625 645 645 ASP ASP B . n B 1 626 PRO 626 646 646 PRO PRO B . n B 1 627 PRO 627 647 647 PRO PRO B . n B 1 628 VAL 628 648 648 VAL VAL B . n B 1 629 VAL 629 649 649 VAL VAL B . n B 1 630 PHE 630 650 650 PHE PHE B . n B 1 631 GLU 631 651 651 GLU GLU B . n B 1 632 GLN 632 652 652 GLN GLN B . n B 1 633 PHE 633 653 653 PHE PHE B . n B 1 634 LEU 634 654 654 LEU LEU B . n B 1 635 HIS 635 655 655 HIS HIS B . n B 1 636 ASN 636 656 656 ASN ASN B . n B 1 637 ASN 637 657 657 ASN ASN B . n B 1 638 GLU 638 658 658 GLU GLU B . n B 1 639 ASN 639 659 659 ASN ASN B . n B 1 640 ILE 640 660 660 ILE ILE B . n B 1 641 GLU 641 661 661 GLU GLU B . n B 1 642 ASN 642 662 662 ASN ASN B . n B 1 643 GLU 643 663 663 GLU GLU B . n B 1 644 ASP 644 664 664 ASP ASP B . n B 1 645 LEU 645 665 665 LEU LEU B . n B 1 646 VAL 646 666 666 VAL VAL B . n B 1 647 ALA 647 667 667 ALA ALA B . n B 1 648 TRP 648 668 668 TRP TRP B . n B 1 649 VAL 649 669 669 VAL VAL B . n B 1 650 THR 650 670 670 THR THR B . n B 1 651 VAL 651 671 671 VAL VAL B . n B 1 652 GLY 652 672 672 GLY GLY B . n B 1 653 PHE 653 673 673 PHE PHE B . n B 1 654 LEU 654 674 674 LEU LEU B . n B 1 655 HIS 655 675 675 HIS HIS B . n B 1 656 ILE 656 676 676 ILE ILE B . n B 1 657 PRO 657 677 677 PRO PRO B . n B 1 658 HIS 658 678 678 HIS HIS B . n B 1 659 SER 659 679 679 SER SER B . n B 1 660 GLU 660 680 680 GLU GLU B . n B 1 661 ASP 661 681 681 ASP ASP B . n B 1 662 ILE 662 682 682 ILE ILE B . n B 1 663 PRO 663 683 683 PRO PRO B . n B 1 664 ASN 664 684 684 ASN ASN B . n B 1 665 THR 665 685 685 THR THR B . n B 1 666 ALA 666 686 686 ALA ALA B . n B 1 667 THR 667 687 687 THR THR B . n B 1 668 PRO 668 688 688 PRO PRO B . n B 1 669 GLY 669 689 689 GLY GLY B . n B 1 670 ASN 670 690 690 ASN ASN B . n B 1 671 SER 671 691 691 SER SER B . n B 1 672 VAL 672 692 692 VAL VAL B . n B 1 673 GLY 673 693 693 GLY GLY B . n B 1 674 PHE 674 694 694 PHE PHE B . n B 1 675 LEU 675 695 695 LEU LEU B . n B 1 676 LEU 676 696 696 LEU LEU B . n B 1 677 ARG 677 697 697 ARG ARG B . n B 1 678 PRO 678 698 698 PRO PRO B . n B 1 679 PHE 679 699 699 PHE PHE B . n B 1 680 ASN 680 700 700 ASN ASN B . n B 1 681 PHE 681 701 701 PHE PHE B . n B 1 682 PHE 682 702 702 PHE PHE B . n B 1 683 PRO 683 703 703 PRO PRO B . n B 1 684 GLU 684 704 704 GLU GLU B . n B 1 685 ASP 685 705 705 ASP ASP B . n B 1 686 PRO 686 706 706 PRO PRO B . n B 1 687 SER 687 707 707 SER SER B . n B 1 688 LEU 688 708 708 LEU LEU B . n B 1 689 ALA 689 709 709 ALA ALA B . n B 1 690 SER 690 710 710 SER SER B . n B 1 691 ARG 691 711 711 ARG ARG B . n B 1 692 ASP 692 712 712 ASP ASP B . n B 1 693 THR 693 713 713 THR THR B . n B 1 694 VAL 694 714 714 VAL VAL B . n B 1 695 ILE 695 715 715 ILE ILE B . n B 1 696 VAL 696 716 716 VAL VAL B . n B 1 697 TRP 697 717 717 TRP TRP B . n B 1 698 PRO 698 718 718 PRO PRO B . n B 1 699 ARG 699 719 719 ARG ARG B . n B 1 700 ASP 700 720 720 ASP ASP B . n B 1 701 ASN 701 721 721 ASN ASN B . n B 1 702 GLY 702 722 722 GLY GLY B . n B 1 703 PRO 703 723 723 PRO PRO B . n B 1 704 ASN 704 724 724 ASN ASN B . n B 1 705 TYR 705 725 725 TYR TYR B . n B 1 706 VAL 706 726 726 VAL VAL B . n B 1 707 GLN 707 727 727 GLN GLN B . n B 1 708 ARG 708 728 728 ARG ARG B . n B 1 709 TRP 709 729 729 TRP TRP B . n B 1 710 ILE 710 730 730 ILE ILE B . n B 1 711 PRO 711 731 731 PRO PRO B . n B 1 712 GLU 712 732 732 GLU GLU B . n B 1 713 ASP 713 733 733 ASP ASP B . n B 1 714 ARG 714 734 734 ARG ARG B . n B 1 715 ASP 715 735 735 ASP ASP B . n B 1 716 CYS 716 736 736 CYS CYS B . n B 1 717 SER 717 737 737 SER SER B . n B 1 718 MET 718 738 738 MET MET B . n B 1 719 PRO 719 739 739 PRO PRO B . n B 1 720 PRO 720 740 740 PRO PRO B . n B 1 721 PRO 721 741 741 PRO PRO B . n B 1 722 PHE 722 742 742 PHE PHE B . n B 1 723 SER 723 743 743 SER SER B . n B 1 724 TYR 724 744 744 TYR TYR B . n B 1 725 ASN 725 745 745 ASN ASN B . n B 1 726 GLY 726 746 746 GLY GLY B . n B 1 727 THR 727 747 747 THR THR B . n B 1 728 TYR 728 748 748 TYR TYR B . n B 1 729 ARG 729 749 749 ARG ARG B . n B 1 730 PRO 730 750 750 PRO PRO B . n B 1 731 VAL 731 751 751 VAL VAL B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 CU 1 801 801 CU CU A . D 3 CA 1 802 802 CA CA A . E 3 CA 1 803 803 CA CA A . F 4 GOL 1 804 804 GOL GOL A . G 5 PNT 1 901 901 PNT PNT A . H 6 NAG 1 1101 1101 NAG NAG A . I 6 NAG 2 1102 1102 NAG NAG A . J 7 BMA 3 1103 1103 BMA BMA A . K 6 NAG 1 5381 5381 NAG NAG A . L 6 NAG 2 5382 5382 NAG NAG A . M 6 NAG 1 7451 7451 NAG NAG A . N 6 NAG 2 7452 7452 NAG NAG A . O 2 CU 1 801 801 CU CU B . P 3 CA 1 802 802 CA CA B . Q 3 CA 1 803 803 CA CA B . R 5 PNT 1 901 901 PNT PNT B . S 6 NAG 1 1101 1101 NAG NAG B . T 6 NAG 2 1102 1102 NAG NAG B . U 6 NAG 1 5381 5381 NAG NAG B . V 6 NAG 2 5382 5382 NAG NAG B . W 6 NAG 1 7451 7451 NAG NAG B . X 6 NAG 2 7452 7452 NAG NAG B . Y 8 HOH 1 2 2 HOH HOH A . Y 8 HOH 2 6 6 HOH HOH A . Y 8 HOH 3 7 7 HOH HOH A . Y 8 HOH 4 8 8 HOH HOH A . Y 8 HOH 5 9 9 HOH HOH A . Y 8 HOH 6 11 11 HOH HOH A . Y 8 HOH 7 12 12 HOH HOH A . Y 8 HOH 8 13 13 HOH HOH A . Y 8 HOH 9 14 14 HOH HOH A . Y 8 HOH 10 16 16 HOH HOH A . Y 8 HOH 11 19 19 HOH HOH A . Y 8 HOH 12 20 20 HOH HOH A . Y 8 HOH 13 752 21 HOH HOH A . Y 8 HOH 14 753 753 HOH HOH A . Y 8 HOH 15 754 754 HOH HOH A . Y 8 HOH 16 755 755 HOH HOH A . Y 8 HOH 17 756 756 HOH HOH A . Y 8 HOH 18 757 22 HOH HOH A . Y 8 HOH 19 758 23 HOH HOH A . Y 8 HOH 20 759 24 HOH HOH A . Y 8 HOH 21 760 25 HOH HOH A . Y 8 HOH 22 761 27 HOH HOH A . Y 8 HOH 23 762 762 HOH HOH A . Y 8 HOH 24 763 28 HOH HOH A . Y 8 HOH 25 764 764 HOH HOH A . Y 8 HOH 26 765 765 HOH HOH A . Y 8 HOH 27 766 31 HOH HOH A . Y 8 HOH 28 767 767 HOH HOH A . Y 8 HOH 29 768 32 HOH HOH A . Y 8 HOH 30 769 769 HOH HOH A . Y 8 HOH 31 770 770 HOH HOH A . Y 8 HOH 32 771 771 HOH HOH A . Y 8 HOH 33 772 34 HOH HOH A . Y 8 HOH 34 773 773 HOH HOH A . Y 8 HOH 35 774 774 HOH HOH A . Y 8 HOH 36 775 36 HOH HOH A . Y 8 HOH 37 776 40 HOH HOH A . Y 8 HOH 38 777 777 HOH HOH A . Y 8 HOH 39 778 41 HOH HOH A . Y 8 HOH 40 779 42 HOH HOH A . Y 8 HOH 41 780 44 HOH HOH A . Y 8 HOH 42 781 46 HOH HOH A . Y 8 HOH 43 782 48 HOH HOH A . Y 8 HOH 44 783 783 HOH HOH A . Y 8 HOH 45 784 784 HOH HOH A . Y 8 HOH 46 785 49 HOH HOH A . Y 8 HOH 47 786 786 HOH HOH A . Y 8 HOH 48 787 52 HOH HOH A . Y 8 HOH 49 788 788 HOH HOH A . Y 8 HOH 50 789 53 HOH HOH A . Y 8 HOH 51 790 56 HOH HOH A . Y 8 HOH 52 791 791 HOH HOH A . Y 8 HOH 53 792 57 HOH HOH A . Y 8 HOH 54 793 59 HOH HOH A . Y 8 HOH 55 794 794 HOH HOH A . Y 8 HOH 56 795 795 HOH HOH A . Y 8 HOH 57 796 796 HOH HOH A . Y 8 HOH 58 797 797 HOH HOH A . Y 8 HOH 59 798 798 HOH HOH A . Y 8 HOH 60 799 60 HOH HOH A . Y 8 HOH 61 800 800 HOH HOH A . Y 8 HOH 62 805 61 HOH HOH A . Y 8 HOH 63 806 62 HOH HOH A . Y 8 HOH 64 807 64 HOH HOH A . Y 8 HOH 65 808 808 HOH HOH A . Y 8 HOH 66 809 65 HOH HOH A . Y 8 HOH 67 810 810 HOH HOH A . Y 8 HOH 68 811 66 HOH HOH A . Y 8 HOH 69 812 67 HOH HOH A . Y 8 HOH 70 813 68 HOH HOH A . Y 8 HOH 71 814 72 HOH HOH A . Y 8 HOH 72 815 73 HOH HOH A . Y 8 HOH 73 816 74 HOH HOH A . Y 8 HOH 74 817 76 HOH HOH A . Y 8 HOH 75 818 77 HOH HOH A . Y 8 HOH 76 819 78 HOH HOH A . Y 8 HOH 77 820 79 HOH HOH A . Y 8 HOH 78 821 82 HOH HOH A . Y 8 HOH 79 822 83 HOH HOH A . Y 8 HOH 80 823 823 HOH HOH A . Y 8 HOH 81 824 824 HOH HOH A . Y 8 HOH 82 825 825 HOH HOH A . Y 8 HOH 83 826 826 HOH HOH A . Y 8 HOH 84 827 84 HOH HOH A . Y 8 HOH 85 828 828 HOH HOH A . Y 8 HOH 86 829 829 HOH HOH A . Y 8 HOH 87 830 85 HOH HOH A . Y 8 HOH 88 831 831 HOH HOH A . Y 8 HOH 89 832 86 HOH HOH A . Y 8 HOH 90 833 833 HOH HOH A . Y 8 HOH 91 834 90 HOH HOH A . Y 8 HOH 92 835 835 HOH HOH A . Y 8 HOH 93 836 836 HOH HOH A . Y 8 HOH 94 837 837 HOH HOH A . Y 8 HOH 95 838 91 HOH HOH A . Y 8 HOH 96 839 839 HOH HOH A . Y 8 HOH 97 840 94 HOH HOH A . Y 8 HOH 98 841 95 HOH HOH A . Y 8 HOH 99 842 98 HOH HOH A . Y 8 HOH 100 843 99 HOH HOH A . Y 8 HOH 101 844 844 HOH HOH A . Y 8 HOH 102 845 100 HOH HOH A . Y 8 HOH 103 846 846 HOH HOH A . Y 8 HOH 104 847 847 HOH HOH A . Y 8 HOH 105 848 101 HOH HOH A . Y 8 HOH 106 849 102 HOH HOH A . Y 8 HOH 107 850 104 HOH HOH A . Y 8 HOH 108 851 851 HOH HOH A . Y 8 HOH 109 852 107 HOH HOH A . Y 8 HOH 110 853 108 HOH HOH A . Y 8 HOH 111 854 854 HOH HOH A . Y 8 HOH 112 855 109 HOH HOH A . Y 8 HOH 113 856 856 HOH HOH A . Y 8 HOH 114 857 857 HOH HOH A . Y 8 HOH 115 858 110 HOH HOH A . Y 8 HOH 116 859 859 HOH HOH A . Y 8 HOH 117 860 860 HOH HOH A . Y 8 HOH 118 861 112 HOH HOH A . Y 8 HOH 119 862 862 HOH HOH A . Y 8 HOH 120 863 863 HOH HOH A . Y 8 HOH 121 864 864 HOH HOH A . Y 8 HOH 122 865 865 HOH HOH A . Y 8 HOH 123 866 866 HOH HOH A . Y 8 HOH 124 867 867 HOH HOH A . Y 8 HOH 125 868 868 HOH HOH A . Y 8 HOH 126 869 869 HOH HOH A . Y 8 HOH 127 870 113 HOH HOH A . Y 8 HOH 128 871 871 HOH HOH A . Y 8 HOH 129 872 114 HOH HOH A . Y 8 HOH 130 873 873 HOH HOH A . Y 8 HOH 131 874 874 HOH HOH A . Y 8 HOH 132 875 115 HOH HOH A . Y 8 HOH 133 876 116 HOH HOH A . Y 8 HOH 134 877 877 HOH HOH A . Y 8 HOH 135 878 120 HOH HOH A . Y 8 HOH 136 879 122 HOH HOH A . Y 8 HOH 137 880 123 HOH HOH A . Y 8 HOH 138 881 881 HOH HOH A . Y 8 HOH 139 882 127 HOH HOH A . Y 8 HOH 140 883 128 HOH HOH A . Y 8 HOH 141 884 884 HOH HOH A . Y 8 HOH 142 885 885 HOH HOH A . Y 8 HOH 143 886 129 HOH HOH A . Y 8 HOH 144 887 133 HOH HOH A . Y 8 HOH 145 888 134 HOH HOH A . Y 8 HOH 146 889 138 HOH HOH A . Y 8 HOH 147 890 890 HOH HOH A . Y 8 HOH 148 891 140 HOH HOH A . Y 8 HOH 149 892 141 HOH HOH A . Y 8 HOH 150 893 151 HOH HOH A . Y 8 HOH 151 894 152 HOH HOH A . Y 8 HOH 152 895 895 HOH HOH A . Y 8 HOH 153 896 896 HOH HOH A . Y 8 HOH 154 897 154 HOH HOH A . Y 8 HOH 155 898 156 HOH HOH A . Y 8 HOH 156 899 163 HOH HOH A . Y 8 HOH 157 900 164 HOH HOH A . Y 8 HOH 158 902 165 HOH HOH A . Y 8 HOH 159 903 903 HOH HOH A . Y 8 HOH 160 904 168 HOH HOH A . Y 8 HOH 161 905 905 HOH HOH A . Y 8 HOH 162 906 906 HOH HOH A . Y 8 HOH 163 907 176 HOH HOH A . Y 8 HOH 164 908 178 HOH HOH A . Y 8 HOH 165 909 179 HOH HOH A . Y 8 HOH 166 910 180 HOH HOH A . Y 8 HOH 167 911 182 HOH HOH A . Y 8 HOH 168 912 185 HOH HOH A . Y 8 HOH 169 913 187 HOH HOH A . Y 8 HOH 170 914 914 HOH HOH A . Y 8 HOH 171 915 915 HOH HOH A . Y 8 HOH 172 916 916 HOH HOH A . Y 8 HOH 173 917 917 HOH HOH A . Y 8 HOH 174 918 190 HOH HOH A . Y 8 HOH 175 919 919 HOH HOH A . Y 8 HOH 176 920 920 HOH HOH A . Y 8 HOH 177 921 191 HOH HOH A . Y 8 HOH 178 922 192 HOH HOH A . Y 8 HOH 179 923 923 HOH HOH A . Y 8 HOH 180 924 924 HOH HOH A . Y 8 HOH 181 925 925 HOH HOH A . Y 8 HOH 182 926 193 HOH HOH A . Y 8 HOH 183 927 195 HOH HOH A . Y 8 HOH 184 928 202 HOH HOH A . Y 8 HOH 185 929 205 HOH HOH A . Y 8 HOH 186 930 206 HOH HOH A . Y 8 HOH 187 931 207 HOH HOH A . Y 8 HOH 188 932 209 HOH HOH A . Y 8 HOH 189 933 212 HOH HOH A . Y 8 HOH 190 934 213 HOH HOH A . Y 8 HOH 191 935 214 HOH HOH A . Y 8 HOH 192 936 215 HOH HOH A . Y 8 HOH 193 937 216 HOH HOH A . Y 8 HOH 194 938 219 HOH HOH A . Y 8 HOH 195 939 221 HOH HOH A . Y 8 HOH 196 940 223 HOH HOH A . Y 8 HOH 197 941 224 HOH HOH A . Y 8 HOH 198 942 225 HOH HOH A . Y 8 HOH 199 943 226 HOH HOH A . Y 8 HOH 200 944 227 HOH HOH A . Y 8 HOH 201 945 228 HOH HOH A . Y 8 HOH 202 946 230 HOH HOH A . Y 8 HOH 203 947 232 HOH HOH A . Y 8 HOH 204 948 234 HOH HOH A . Y 8 HOH 205 949 235 HOH HOH A . Y 8 HOH 206 950 242 HOH HOH A . Y 8 HOH 207 951 245 HOH HOH A . Y 8 HOH 208 952 246 HOH HOH A . Y 8 HOH 209 953 248 HOH HOH A . Y 8 HOH 210 954 249 HOH HOH A . Y 8 HOH 211 955 251 HOH HOH A . Y 8 HOH 212 956 252 HOH HOH A . Y 8 HOH 213 957 254 HOH HOH A . Y 8 HOH 214 958 255 HOH HOH A . Y 8 HOH 215 959 256 HOH HOH A . Y 8 HOH 216 960 257 HOH HOH A . Y 8 HOH 217 961 258 HOH HOH A . Y 8 HOH 218 962 262 HOH HOH A . Y 8 HOH 219 963 267 HOH HOH A . Y 8 HOH 220 964 268 HOH HOH A . Y 8 HOH 221 965 270 HOH HOH A . Y 8 HOH 222 966 271 HOH HOH A . Y 8 HOH 223 967 273 HOH HOH A . Y 8 HOH 224 968 275 HOH HOH A . Y 8 HOH 225 969 276 HOH HOH A . Y 8 HOH 226 970 277 HOH HOH A . Y 8 HOH 227 971 279 HOH HOH A . Y 8 HOH 228 972 281 HOH HOH A . Y 8 HOH 229 973 282 HOH HOH A . Y 8 HOH 230 974 284 HOH HOH A . Y 8 HOH 231 975 285 HOH HOH A . Y 8 HOH 232 976 289 HOH HOH A . Y 8 HOH 233 977 290 HOH HOH A . Y 8 HOH 234 978 292 HOH HOH A . Y 8 HOH 235 979 293 HOH HOH A . Y 8 HOH 236 980 296 HOH HOH A . Y 8 HOH 237 981 300 HOH HOH A . Y 8 HOH 238 982 305 HOH HOH A . Y 8 HOH 239 983 306 HOH HOH A . Y 8 HOH 240 984 307 HOH HOH A . Y 8 HOH 241 985 308 HOH HOH A . Y 8 HOH 242 986 310 HOH HOH A . Y 8 HOH 243 987 315 HOH HOH A . Y 8 HOH 244 988 317 HOH HOH A . Y 8 HOH 245 989 318 HOH HOH A . Y 8 HOH 246 990 319 HOH HOH A . Y 8 HOH 247 991 320 HOH HOH A . Y 8 HOH 248 992 321 HOH HOH A . Y 8 HOH 249 993 322 HOH HOH A . Y 8 HOH 250 994 323 HOH HOH A . Y 8 HOH 251 995 324 HOH HOH A . Y 8 HOH 252 996 325 HOH HOH A . Y 8 HOH 253 997 326 HOH HOH A . Y 8 HOH 254 998 327 HOH HOH A . Y 8 HOH 255 999 328 HOH HOH A . Y 8 HOH 256 1000 329 HOH HOH A . Y 8 HOH 257 1001 330 HOH HOH A . Y 8 HOH 258 1002 331 HOH HOH A . Y 8 HOH 259 1003 332 HOH HOH A . Y 8 HOH 260 1004 333 HOH HOH A . Y 8 HOH 261 1005 335 HOH HOH A . Y 8 HOH 262 1006 338 HOH HOH A . Y 8 HOH 263 1007 340 HOH HOH A . Y 8 HOH 264 1008 344 HOH HOH A . Y 8 HOH 265 1009 347 HOH HOH A . Y 8 HOH 266 1010 348 HOH HOH A . Y 8 HOH 267 1011 350 HOH HOH A . Y 8 HOH 268 1012 352 HOH HOH A . Y 8 HOH 269 1013 353 HOH HOH A . Y 8 HOH 270 1014 354 HOH HOH A . Y 8 HOH 271 1015 357 HOH HOH A . Y 8 HOH 272 1016 358 HOH HOH A . Y 8 HOH 273 1017 359 HOH HOH A . Y 8 HOH 274 1018 361 HOH HOH A . Y 8 HOH 275 1019 363 HOH HOH A . Y 8 HOH 276 1020 365 HOH HOH A . Y 8 HOH 277 1021 366 HOH HOH A . Y 8 HOH 278 1022 369 HOH HOH A . Y 8 HOH 279 1023 371 HOH HOH A . Y 8 HOH 280 1024 372 HOH HOH A . Y 8 HOH 281 1025 374 HOH HOH A . Y 8 HOH 282 1026 375 HOH HOH A . Y 8 HOH 283 1027 376 HOH HOH A . Y 8 HOH 284 1028 378 HOH HOH A . Y 8 HOH 285 1029 380 HOH HOH A . Y 8 HOH 286 1030 381 HOH HOH A . Y 8 HOH 287 1031 383 HOH HOH A . Y 8 HOH 288 1032 385 HOH HOH A . Y 8 HOH 289 1033 387 HOH HOH A . Y 8 HOH 290 1034 391 HOH HOH A . Y 8 HOH 291 1035 393 HOH HOH A . Y 8 HOH 292 1036 394 HOH HOH A . Y 8 HOH 293 1037 396 HOH HOH A . Y 8 HOH 294 1038 398 HOH HOH A . Y 8 HOH 295 1039 399 HOH HOH A . Y 8 HOH 296 1040 400 HOH HOH A . Y 8 HOH 297 1041 405 HOH HOH A . Y 8 HOH 298 1042 406 HOH HOH A . Y 8 HOH 299 1043 408 HOH HOH A . Y 8 HOH 300 1044 410 HOH HOH A . Y 8 HOH 301 1045 413 HOH HOH A . Y 8 HOH 302 1046 415 HOH HOH A . Y 8 HOH 303 1047 416 HOH HOH A . Y 8 HOH 304 1048 423 HOH HOH A . Y 8 HOH 305 1049 424 HOH HOH A . Y 8 HOH 306 1050 425 HOH HOH A . Y 8 HOH 307 1051 426 HOH HOH A . Y 8 HOH 308 1052 433 HOH HOH A . Y 8 HOH 309 1053 436 HOH HOH A . Y 8 HOH 310 1054 441 HOH HOH A . Y 8 HOH 311 1055 446 HOH HOH A . Y 8 HOH 312 1056 448 HOH HOH A . Y 8 HOH 313 1057 451 HOH HOH A . Y 8 HOH 314 1058 452 HOH HOH A . Y 8 HOH 315 1059 455 HOH HOH A . Y 8 HOH 316 1060 456 HOH HOH A . Y 8 HOH 317 1061 459 HOH HOH A . Y 8 HOH 318 1062 460 HOH HOH A . Y 8 HOH 319 1063 463 HOH HOH A . Y 8 HOH 320 1064 465 HOH HOH A . Y 8 HOH 321 1065 468 HOH HOH A . Y 8 HOH 322 1066 469 HOH HOH A . Y 8 HOH 323 1067 471 HOH HOH A . Y 8 HOH 324 1068 472 HOH HOH A . Y 8 HOH 325 1069 473 HOH HOH A . Y 8 HOH 326 1070 474 HOH HOH A . Y 8 HOH 327 1071 476 HOH HOH A . Y 8 HOH 328 1072 477 HOH HOH A . Y 8 HOH 329 1073 478 HOH HOH A . Y 8 HOH 330 1074 480 HOH HOH A . Y 8 HOH 331 1075 482 HOH HOH A . Y 8 HOH 332 1076 484 HOH HOH A . Y 8 HOH 333 1077 485 HOH HOH A . Y 8 HOH 334 1078 486 HOH HOH A . Y 8 HOH 335 1079 489 HOH HOH A . Y 8 HOH 336 1080 491 HOH HOH A . Y 8 HOH 337 1081 495 HOH HOH A . Y 8 HOH 338 1082 496 HOH HOH A . Y 8 HOH 339 1083 501 HOH HOH A . Y 8 HOH 340 1084 503 HOH HOH A . Y 8 HOH 341 1085 504 HOH HOH A . Y 8 HOH 342 1086 505 HOH HOH A . Y 8 HOH 343 1087 506 HOH HOH A . Y 8 HOH 344 1088 507 HOH HOH A . Y 8 HOH 345 1089 512 HOH HOH A . Y 8 HOH 346 1090 513 HOH HOH A . Y 8 HOH 347 1091 514 HOH HOH A . Y 8 HOH 348 1092 515 HOH HOH A . Y 8 HOH 349 1093 517 HOH HOH A . Y 8 HOH 350 1094 519 HOH HOH A . Y 8 HOH 351 1095 520 HOH HOH A . Y 8 HOH 352 1096 522 HOH HOH A . Y 8 HOH 353 1097 526 HOH HOH A . Y 8 HOH 354 1098 530 HOH HOH A . Y 8 HOH 355 1099 533 HOH HOH A . Y 8 HOH 356 1100 534 HOH HOH A . Y 8 HOH 357 1104 536 HOH HOH A . Y 8 HOH 358 1105 540 HOH HOH A . Y 8 HOH 359 1106 542 HOH HOH A . Y 8 HOH 360 1107 543 HOH HOH A . Y 8 HOH 361 1108 546 HOH HOH A . Y 8 HOH 362 1109 547 HOH HOH A . Y 8 HOH 363 1110 549 HOH HOH A . Y 8 HOH 364 1111 556 HOH HOH A . Y 8 HOH 365 1112 558 HOH HOH A . Y 8 HOH 366 1113 561 HOH HOH A . Y 8 HOH 367 1114 562 HOH HOH A . Y 8 HOH 368 1115 563 HOH HOH A . Y 8 HOH 369 1116 566 HOH HOH A . Y 8 HOH 370 1117 567 HOH HOH A . Y 8 HOH 371 1118 575 HOH HOH A . Y 8 HOH 372 1119 576 HOH HOH A . Y 8 HOH 373 1120 580 HOH HOH A . Y 8 HOH 374 1121 588 HOH HOH A . Y 8 HOH 375 1122 592 HOH HOH A . Y 8 HOH 376 1123 595 HOH HOH A . Y 8 HOH 377 1124 598 HOH HOH A . Y 8 HOH 378 1125 599 HOH HOH A . Y 8 HOH 379 1126 600 HOH HOH A . Y 8 HOH 380 1127 602 HOH HOH A . Y 8 HOH 381 1128 604 HOH HOH A . Y 8 HOH 382 1129 605 HOH HOH A . Y 8 HOH 383 1130 606 HOH HOH A . Y 8 HOH 384 1131 609 HOH HOH A . Y 8 HOH 385 1132 610 HOH HOH A . Y 8 HOH 386 1133 611 HOH HOH A . Y 8 HOH 387 1134 615 HOH HOH A . Y 8 HOH 388 1135 616 HOH HOH A . Y 8 HOH 389 1136 617 HOH HOH A . Y 8 HOH 390 1137 618 HOH HOH A . Y 8 HOH 391 1138 621 HOH HOH A . Y 8 HOH 392 1139 622 HOH HOH A . Y 8 HOH 393 1140 623 HOH HOH A . Y 8 HOH 394 1141 624 HOH HOH A . Y 8 HOH 395 1142 625 HOH HOH A . Y 8 HOH 396 1143 628 HOH HOH A . Y 8 HOH 397 1144 629 HOH HOH A . Y 8 HOH 398 1145 630 HOH HOH A . Y 8 HOH 399 1146 631 HOH HOH A . Y 8 HOH 400 1147 636 HOH HOH A . Y 8 HOH 401 1148 639 HOH HOH A . Y 8 HOH 402 1149 640 HOH HOH A . Y 8 HOH 403 1150 642 HOH HOH A . Y 8 HOH 404 1151 645 HOH HOH A . Y 8 HOH 405 1152 646 HOH HOH A . Y 8 HOH 406 1153 647 HOH HOH A . Y 8 HOH 407 1154 648 HOH HOH A . Y 8 HOH 408 1155 649 HOH HOH A . Y 8 HOH 409 1156 650 HOH HOH A . Y 8 HOH 410 1157 651 HOH HOH A . Y 8 HOH 411 1158 656 HOH HOH A . Y 8 HOH 412 1159 657 HOH HOH A . Y 8 HOH 413 1160 660 HOH HOH A . Y 8 HOH 414 1161 662 HOH HOH A . Y 8 HOH 415 1162 669 HOH HOH A . Y 8 HOH 416 1163 671 HOH HOH A . Y 8 HOH 417 1164 673 HOH HOH A . Y 8 HOH 418 1165 674 HOH HOH A . Y 8 HOH 419 1166 675 HOH HOH A . Y 8 HOH 420 1167 677 HOH HOH A . Y 8 HOH 421 1168 678 HOH HOH A . Y 8 HOH 422 1169 679 HOH HOH A . Y 8 HOH 423 1170 680 HOH HOH A . Y 8 HOH 424 1171 682 HOH HOH A . Y 8 HOH 425 1172 683 HOH HOH A . Y 8 HOH 426 1173 691 HOH HOH A . Y 8 HOH 427 1174 692 HOH HOH A . Y 8 HOH 428 1175 693 HOH HOH A . Y 8 HOH 429 1176 694 HOH HOH A . Y 8 HOH 430 1177 695 HOH HOH A . Y 8 HOH 431 1178 696 HOH HOH A . Y 8 HOH 432 1179 699 HOH HOH A . Y 8 HOH 433 1180 702 HOH HOH A . Y 8 HOH 434 1181 704 HOH HOH A . Y 8 HOH 435 1182 705 HOH HOH A . Y 8 HOH 436 1183 708 HOH HOH A . Y 8 HOH 437 1184 709 HOH HOH A . Y 8 HOH 438 1185 710 HOH HOH A . Y 8 HOH 439 1186 711 HOH HOH A . Y 8 HOH 440 1187 712 HOH HOH A . Y 8 HOH 441 1188 714 HOH HOH A . Y 8 HOH 442 1189 716 HOH HOH A . Y 8 HOH 443 1190 718 HOH HOH A . Y 8 HOH 444 1191 719 HOH HOH A . Y 8 HOH 445 1192 721 HOH HOH A . Y 8 HOH 446 1193 722 HOH HOH A . Y 8 HOH 447 1194 723 HOH HOH A . Y 8 HOH 448 1195 728 HOH HOH A . Y 8 HOH 449 1196 732 HOH HOH A . Y 8 HOH 450 1197 734 HOH HOH A . Y 8 HOH 451 1198 735 HOH HOH A . Y 8 HOH 452 1199 736 HOH HOH A . Y 8 HOH 453 1200 737 HOH HOH A . Y 8 HOH 454 1201 740 HOH HOH A . Y 8 HOH 455 1202 741 HOH HOH A . Y 8 HOH 456 1203 747 HOH HOH A . Y 8 HOH 457 1204 801 HOH HOH A . Y 8 HOH 458 1205 901 HOH HOH A . Y 8 HOH 459 1206 411 HOH HOH A . Y 8 HOH 460 1207 412 HOH HOH A . Z 8 HOH 1 1 1 HOH HOH B . Z 8 HOH 2 3 3 HOH HOH B . Z 8 HOH 3 4 4 HOH HOH B . Z 8 HOH 4 5 5 HOH HOH B . Z 8 HOH 5 10 10 HOH HOH B . Z 8 HOH 6 15 15 HOH HOH B . Z 8 HOH 7 17 17 HOH HOH B . Z 8 HOH 8 18 18 HOH HOH B . Z 8 HOH 9 752 752 HOH HOH B . Z 8 HOH 10 753 26 HOH HOH B . Z 8 HOH 11 754 29 HOH HOH B . Z 8 HOH 12 755 30 HOH HOH B . Z 8 HOH 13 756 33 HOH HOH B . Z 8 HOH 14 757 757 HOH HOH B . Z 8 HOH 15 758 35 HOH HOH B . Z 8 HOH 16 759 759 HOH HOH B . Z 8 HOH 17 760 760 HOH HOH B . Z 8 HOH 18 761 761 HOH HOH B . Z 8 HOH 19 762 37 HOH HOH B . Z 8 HOH 20 763 763 HOH HOH B . Z 8 HOH 21 764 38 HOH HOH B . Z 8 HOH 22 765 39 HOH HOH B . Z 8 HOH 23 766 766 HOH HOH B . Z 8 HOH 24 767 43 HOH HOH B . Z 8 HOH 25 768 768 HOH HOH B . Z 8 HOH 26 769 45 HOH HOH B . Z 8 HOH 27 770 47 HOH HOH B . Z 8 HOH 28 771 50 HOH HOH B . Z 8 HOH 29 772 772 HOH HOH B . Z 8 HOH 30 773 51 HOH HOH B . Z 8 HOH 31 774 54 HOH HOH B . Z 8 HOH 32 775 775 HOH HOH B . Z 8 HOH 33 776 55 HOH HOH B . Z 8 HOH 34 777 58 HOH HOH B . Z 8 HOH 35 778 778 HOH HOH B . Z 8 HOH 36 779 779 HOH HOH B . Z 8 HOH 37 780 780 HOH HOH B . Z 8 HOH 38 781 781 HOH HOH B . Z 8 HOH 39 782 782 HOH HOH B . Z 8 HOH 40 783 63 HOH HOH B . Z 8 HOH 41 784 69 HOH HOH B . Z 8 HOH 42 785 70 HOH HOH B . Z 8 HOH 43 786 71 HOH HOH B . Z 8 HOH 44 787 787 HOH HOH B . Z 8 HOH 45 788 75 HOH HOH B . Z 8 HOH 46 789 789 HOH HOH B . Z 8 HOH 47 790 790 HOH HOH B . Z 8 HOH 48 791 80 HOH HOH B . Z 8 HOH 49 792 792 HOH HOH B . Z 8 HOH 50 793 793 HOH HOH B . Z 8 HOH 51 794 81 HOH HOH B . Z 8 HOH 52 795 87 HOH HOH B . Z 8 HOH 53 796 88 HOH HOH B . Z 8 HOH 54 797 89 HOH HOH B . Z 8 HOH 55 798 92 HOH HOH B . Z 8 HOH 56 799 799 HOH HOH B . Z 8 HOH 57 800 93 HOH HOH B . Z 8 HOH 58 804 804 HOH HOH B . Z 8 HOH 59 805 805 HOH HOH B . Z 8 HOH 60 806 806 HOH HOH B . Z 8 HOH 61 807 807 HOH HOH B . Z 8 HOH 62 808 96 HOH HOH B . Z 8 HOH 63 809 809 HOH HOH B . Z 8 HOH 64 810 97 HOH HOH B . Z 8 HOH 65 811 811 HOH HOH B . Z 8 HOH 66 812 812 HOH HOH B . Z 8 HOH 67 813 813 HOH HOH B . Z 8 HOH 68 814 814 HOH HOH B . Z 8 HOH 69 815 815 HOH HOH B . Z 8 HOH 70 816 816 HOH HOH B . Z 8 HOH 71 817 817 HOH HOH B . Z 8 HOH 72 818 818 HOH HOH B . Z 8 HOH 73 819 819 HOH HOH B . Z 8 HOH 74 820 820 HOH HOH B . Z 8 HOH 75 821 821 HOH HOH B . Z 8 HOH 76 822 822 HOH HOH B . Z 8 HOH 77 823 103 HOH HOH B . Z 8 HOH 78 824 105 HOH HOH B . Z 8 HOH 79 825 106 HOH HOH B . Z 8 HOH 80 826 111 HOH HOH B . Z 8 HOH 81 827 827 HOH HOH B . Z 8 HOH 82 828 117 HOH HOH B . Z 8 HOH 83 829 118 HOH HOH B . Z 8 HOH 84 830 830 HOH HOH B . Z 8 HOH 85 831 119 HOH HOH B . Z 8 HOH 86 832 832 HOH HOH B . Z 8 HOH 87 833 121 HOH HOH B . Z 8 HOH 88 834 834 HOH HOH B . Z 8 HOH 89 835 124 HOH HOH B . Z 8 HOH 90 836 125 HOH HOH B . Z 8 HOH 91 837 126 HOH HOH B . Z 8 HOH 92 838 130 HOH HOH B . Z 8 HOH 93 839 131 HOH HOH B . Z 8 HOH 94 840 132 HOH HOH B . Z 8 HOH 95 841 841 HOH HOH B . Z 8 HOH 96 842 842 HOH HOH B . Z 8 HOH 97 843 843 HOH HOH B . Z 8 HOH 98 844 135 HOH HOH B . Z 8 HOH 99 845 845 HOH HOH B . Z 8 HOH 100 846 136 HOH HOH B . Z 8 HOH 101 847 137 HOH HOH B . Z 8 HOH 102 848 848 HOH HOH B . Z 8 HOH 103 849 849 HOH HOH B . Z 8 HOH 104 850 850 HOH HOH B . Z 8 HOH 105 851 139 HOH HOH B . Z 8 HOH 106 852 852 HOH HOH B . Z 8 HOH 107 853 853 HOH HOH B . Z 8 HOH 108 854 142 HOH HOH B . Z 8 HOH 109 855 855 HOH HOH B . Z 8 HOH 110 856 143 HOH HOH B . Z 8 HOH 111 857 144 HOH HOH B . Z 8 HOH 112 858 858 HOH HOH B . Z 8 HOH 113 859 145 HOH HOH B . Z 8 HOH 114 860 146 HOH HOH B . Z 8 HOH 115 861 147 HOH HOH B . Z 8 HOH 116 862 148 HOH HOH B . Z 8 HOH 117 863 149 HOH HOH B . Z 8 HOH 118 864 150 HOH HOH B . Z 8 HOH 119 865 153 HOH HOH B . Z 8 HOH 120 866 155 HOH HOH B . Z 8 HOH 121 867 157 HOH HOH B . Z 8 HOH 122 868 158 HOH HOH B . Z 8 HOH 123 869 159 HOH HOH B . Z 8 HOH 124 870 160 HOH HOH B . Z 8 HOH 125 871 161 HOH HOH B . Z 8 HOH 126 872 872 HOH HOH B . Z 8 HOH 127 873 162 HOH HOH B . Z 8 HOH 128 874 166 HOH HOH B . Z 8 HOH 129 875 875 HOH HOH B . Z 8 HOH 130 876 167 HOH HOH B . Z 8 HOH 131 877 169 HOH HOH B . Z 8 HOH 132 878 878 HOH HOH B . Z 8 HOH 133 879 879 HOH HOH B . Z 8 HOH 134 880 880 HOH HOH B . Z 8 HOH 135 881 170 HOH HOH B . Z 8 HOH 136 882 882 HOH HOH B . Z 8 HOH 137 883 883 HOH HOH B . Z 8 HOH 138 884 171 HOH HOH B . Z 8 HOH 139 885 172 HOH HOH B . Z 8 HOH 140 886 886 HOH HOH B . Z 8 HOH 141 887 887 HOH HOH B . Z 8 HOH 142 888 888 HOH HOH B . Z 8 HOH 143 889 889 HOH HOH B . Z 8 HOH 144 890 173 HOH HOH B . Z 8 HOH 145 891 891 HOH HOH B . Z 8 HOH 146 892 892 HOH HOH B . Z 8 HOH 147 893 893 HOH HOH B . Z 8 HOH 148 894 894 HOH HOH B . Z 8 HOH 149 895 174 HOH HOH B . Z 8 HOH 150 896 175 HOH HOH B . Z 8 HOH 151 897 897 HOH HOH B . Z 8 HOH 152 898 898 HOH HOH B . Z 8 HOH 153 899 899 HOH HOH B . Z 8 HOH 154 900 900 HOH HOH B . Z 8 HOH 155 902 902 HOH HOH B . Z 8 HOH 156 903 177 HOH HOH B . Z 8 HOH 157 904 904 HOH HOH B . Z 8 HOH 158 905 181 HOH HOH B . Z 8 HOH 159 906 183 HOH HOH B . Z 8 HOH 160 907 907 HOH HOH B . Z 8 HOH 161 908 908 HOH HOH B . Z 8 HOH 162 909 909 HOH HOH B . Z 8 HOH 163 910 910 HOH HOH B . Z 8 HOH 164 911 911 HOH HOH B . Z 8 HOH 165 912 912 HOH HOH B . Z 8 HOH 166 913 913 HOH HOH B . Z 8 HOH 167 914 184 HOH HOH B . Z 8 HOH 168 915 186 HOH HOH B . Z 8 HOH 169 916 188 HOH HOH B . Z 8 HOH 170 917 189 HOH HOH B . Z 8 HOH 171 918 918 HOH HOH B . Z 8 HOH 172 919 194 HOH HOH B . Z 8 HOH 173 920 196 HOH HOH B . Z 8 HOH 174 921 921 HOH HOH B . Z 8 HOH 175 922 922 HOH HOH B . Z 8 HOH 176 923 197 HOH HOH B . Z 8 HOH 177 924 198 HOH HOH B . Z 8 HOH 178 925 199 HOH HOH B . Z 8 HOH 179 926 200 HOH HOH B . Z 8 HOH 180 927 927 HOH HOH B . Z 8 HOH 181 928 928 HOH HOH B . Z 8 HOH 182 929 929 HOH HOH B . Z 8 HOH 183 930 930 HOH HOH B . Z 8 HOH 184 931 931 HOH HOH B . Z 8 HOH 185 932 932 HOH HOH B . Z 8 HOH 186 933 201 HOH HOH B . Z 8 HOH 187 934 203 HOH HOH B . Z 8 HOH 188 935 204 HOH HOH B . Z 8 HOH 189 936 208 HOH HOH B . Z 8 HOH 190 937 210 HOH HOH B . Z 8 HOH 191 938 211 HOH HOH B . Z 8 HOH 192 939 217 HOH HOH B . Z 8 HOH 193 940 218 HOH HOH B . Z 8 HOH 194 941 220 HOH HOH B . Z 8 HOH 195 942 222 HOH HOH B . Z 8 HOH 196 943 229 HOH HOH B . Z 8 HOH 197 944 231 HOH HOH B . Z 8 HOH 198 945 233 HOH HOH B . Z 8 HOH 199 946 236 HOH HOH B . Z 8 HOH 200 947 237 HOH HOH B . Z 8 HOH 201 948 238 HOH HOH B . Z 8 HOH 202 949 239 HOH HOH B . Z 8 HOH 203 950 240 HOH HOH B . Z 8 HOH 204 951 241 HOH HOH B . Z 8 HOH 205 952 243 HOH HOH B . Z 8 HOH 206 953 244 HOH HOH B . Z 8 HOH 207 954 247 HOH HOH B . Z 8 HOH 208 955 250 HOH HOH B . Z 8 HOH 209 956 253 HOH HOH B . Z 8 HOH 210 957 259 HOH HOH B . Z 8 HOH 211 958 260 HOH HOH B . Z 8 HOH 212 959 261 HOH HOH B . Z 8 HOH 213 960 263 HOH HOH B . Z 8 HOH 214 961 264 HOH HOH B . Z 8 HOH 215 962 265 HOH HOH B . Z 8 HOH 216 963 266 HOH HOH B . Z 8 HOH 217 964 269 HOH HOH B . Z 8 HOH 218 965 272 HOH HOH B . Z 8 HOH 219 966 274 HOH HOH B . Z 8 HOH 220 967 278 HOH HOH B . Z 8 HOH 221 968 280 HOH HOH B . Z 8 HOH 222 969 283 HOH HOH B . Z 8 HOH 223 970 286 HOH HOH B . Z 8 HOH 224 971 287 HOH HOH B . Z 8 HOH 225 972 288 HOH HOH B . Z 8 HOH 226 973 291 HOH HOH B . Z 8 HOH 227 974 294 HOH HOH B . Z 8 HOH 228 975 295 HOH HOH B . Z 8 HOH 229 976 297 HOH HOH B . Z 8 HOH 230 977 298 HOH HOH B . Z 8 HOH 231 978 299 HOH HOH B . Z 8 HOH 232 979 301 HOH HOH B . Z 8 HOH 233 980 302 HOH HOH B . Z 8 HOH 234 981 303 HOH HOH B . Z 8 HOH 235 982 304 HOH HOH B . Z 8 HOH 236 983 309 HOH HOH B . Z 8 HOH 237 984 311 HOH HOH B . Z 8 HOH 238 985 312 HOH HOH B . Z 8 HOH 239 986 313 HOH HOH B . Z 8 HOH 240 987 314 HOH HOH B . Z 8 HOH 241 988 316 HOH HOH B . Z 8 HOH 242 989 334 HOH HOH B . Z 8 HOH 243 990 336 HOH HOH B . Z 8 HOH 244 991 337 HOH HOH B . Z 8 HOH 245 992 339 HOH HOH B . Z 8 HOH 246 993 341 HOH HOH B . Z 8 HOH 247 994 342 HOH HOH B . Z 8 HOH 248 995 343 HOH HOH B . Z 8 HOH 249 996 345 HOH HOH B . Z 8 HOH 250 997 346 HOH HOH B . Z 8 HOH 251 998 349 HOH HOH B . Z 8 HOH 252 999 351 HOH HOH B . Z 8 HOH 253 1000 355 HOH HOH B . Z 8 HOH 254 1001 356 HOH HOH B . Z 8 HOH 255 1002 360 HOH HOH B . Z 8 HOH 256 1003 362 HOH HOH B . Z 8 HOH 257 1004 364 HOH HOH B . Z 8 HOH 258 1005 367 HOH HOH B . Z 8 HOH 259 1006 368 HOH HOH B . Z 8 HOH 260 1007 370 HOH HOH B . Z 8 HOH 261 1008 373 HOH HOH B . Z 8 HOH 262 1009 377 HOH HOH B . Z 8 HOH 263 1010 379 HOH HOH B . Z 8 HOH 264 1011 382 HOH HOH B . Z 8 HOH 265 1012 384 HOH HOH B . Z 8 HOH 266 1013 386 HOH HOH B . Z 8 HOH 267 1014 388 HOH HOH B . Z 8 HOH 268 1015 389 HOH HOH B . Z 8 HOH 269 1016 390 HOH HOH B . Z 8 HOH 270 1017 392 HOH HOH B . Z 8 HOH 271 1018 395 HOH HOH B . Z 8 HOH 272 1019 397 HOH HOH B . Z 8 HOH 273 1020 401 HOH HOH B . Z 8 HOH 274 1021 402 HOH HOH B . Z 8 HOH 275 1022 404 HOH HOH B . Z 8 HOH 276 1023 407 HOH HOH B . Z 8 HOH 277 1024 409 HOH HOH B . Z 8 HOH 278 1027 414 HOH HOH B . Z 8 HOH 279 1028 417 HOH HOH B . Z 8 HOH 280 1029 418 HOH HOH B . Z 8 HOH 281 1030 419 HOH HOH B . Z 8 HOH 282 1031 420 HOH HOH B . Z 8 HOH 283 1032 421 HOH HOH B . Z 8 HOH 284 1033 422 HOH HOH B . Z 8 HOH 285 1034 427 HOH HOH B . Z 8 HOH 286 1035 428 HOH HOH B . Z 8 HOH 287 1036 429 HOH HOH B . Z 8 HOH 288 1037 430 HOH HOH B . Z 8 HOH 289 1038 431 HOH HOH B . Z 8 HOH 290 1039 432 HOH HOH B . Z 8 HOH 291 1040 434 HOH HOH B . Z 8 HOH 292 1041 435 HOH HOH B . Z 8 HOH 293 1042 437 HOH HOH B . Z 8 HOH 294 1043 438 HOH HOH B . Z 8 HOH 295 1044 439 HOH HOH B . Z 8 HOH 296 1045 440 HOH HOH B . Z 8 HOH 297 1046 442 HOH HOH B . Z 8 HOH 298 1047 443 HOH HOH B . Z 8 HOH 299 1048 444 HOH HOH B . Z 8 HOH 300 1049 445 HOH HOH B . Z 8 HOH 301 1050 447 HOH HOH B . Z 8 HOH 302 1051 449 HOH HOH B . Z 8 HOH 303 1052 450 HOH HOH B . Z 8 HOH 304 1053 453 HOH HOH B . Z 8 HOH 305 1054 454 HOH HOH B . Z 8 HOH 306 1055 457 HOH HOH B . Z 8 HOH 307 1056 458 HOH HOH B . Z 8 HOH 308 1057 461 HOH HOH B . Z 8 HOH 309 1058 462 HOH HOH B . Z 8 HOH 310 1059 464 HOH HOH B . Z 8 HOH 311 1060 466 HOH HOH B . Z 8 HOH 312 1061 467 HOH HOH B . Z 8 HOH 313 1062 470 HOH HOH B . Z 8 HOH 314 1063 475 HOH HOH B . Z 8 HOH 315 1064 479 HOH HOH B . Z 8 HOH 316 1065 481 HOH HOH B . Z 8 HOH 317 1066 483 HOH HOH B . Z 8 HOH 318 1067 487 HOH HOH B . Z 8 HOH 319 1068 488 HOH HOH B . Z 8 HOH 320 1069 490 HOH HOH B . Z 8 HOH 321 1070 492 HOH HOH B . Z 8 HOH 322 1071 493 HOH HOH B . Z 8 HOH 323 1072 494 HOH HOH B . Z 8 HOH 324 1073 497 HOH HOH B . Z 8 HOH 325 1074 498 HOH HOH B . Z 8 HOH 326 1075 499 HOH HOH B . Z 8 HOH 327 1076 500 HOH HOH B . Z 8 HOH 328 1077 502 HOH HOH B . Z 8 HOH 329 1078 508 HOH HOH B . Z 8 HOH 330 1079 509 HOH HOH B . Z 8 HOH 331 1080 510 HOH HOH B . Z 8 HOH 332 1081 511 HOH HOH B . Z 8 HOH 333 1082 516 HOH HOH B . Z 8 HOH 334 1083 518 HOH HOH B . Z 8 HOH 335 1084 521 HOH HOH B . Z 8 HOH 336 1085 523 HOH HOH B . Z 8 HOH 337 1086 524 HOH HOH B . Z 8 HOH 338 1087 525 HOH HOH B . Z 8 HOH 339 1088 527 HOH HOH B . Z 8 HOH 340 1089 528 HOH HOH B . Z 8 HOH 341 1090 529 HOH HOH B . Z 8 HOH 342 1091 531 HOH HOH B . Z 8 HOH 343 1092 532 HOH HOH B . Z 8 HOH 344 1093 535 HOH HOH B . Z 8 HOH 345 1094 537 HOH HOH B . Z 8 HOH 346 1095 538 HOH HOH B . Z 8 HOH 347 1096 539 HOH HOH B . Z 8 HOH 348 1097 541 HOH HOH B . Z 8 HOH 349 1098 545 HOH HOH B . Z 8 HOH 350 1099 548 HOH HOH B . Z 8 HOH 351 1100 550 HOH HOH B . Z 8 HOH 352 1103 551 HOH HOH B . Z 8 HOH 353 1104 552 HOH HOH B . Z 8 HOH 354 1105 553 HOH HOH B . Z 8 HOH 355 1106 555 HOH HOH B . Z 8 HOH 356 1107 557 HOH HOH B . Z 8 HOH 357 1108 559 HOH HOH B . Z 8 HOH 358 1109 560 HOH HOH B . Z 8 HOH 359 1110 564 HOH HOH B . Z 8 HOH 360 1111 565 HOH HOH B . Z 8 HOH 361 1112 568 HOH HOH B . Z 8 HOH 362 1113 569 HOH HOH B . Z 8 HOH 363 1114 570 HOH HOH B . Z 8 HOH 364 1115 571 HOH HOH B . Z 8 HOH 365 1116 572 HOH HOH B . Z 8 HOH 366 1117 573 HOH HOH B . Z 8 HOH 367 1118 574 HOH HOH B . Z 8 HOH 368 1119 577 HOH HOH B . Z 8 HOH 369 1120 578 HOH HOH B . Z 8 HOH 370 1121 579 HOH HOH B . Z 8 HOH 371 1122 581 HOH HOH B . Z 8 HOH 372 1123 582 HOH HOH B . Z 8 HOH 373 1124 583 HOH HOH B . Z 8 HOH 374 1125 584 HOH HOH B . Z 8 HOH 375 1126 585 HOH HOH B . Z 8 HOH 376 1127 586 HOH HOH B . Z 8 HOH 377 1128 589 HOH HOH B . Z 8 HOH 378 1129 590 HOH HOH B . Z 8 HOH 379 1130 591 HOH HOH B . Z 8 HOH 380 1131 593 HOH HOH B . Z 8 HOH 381 1132 594 HOH HOH B . Z 8 HOH 382 1133 596 HOH HOH B . Z 8 HOH 383 1134 597 HOH HOH B . Z 8 HOH 384 1135 601 HOH HOH B . Z 8 HOH 385 1136 603 HOH HOH B . Z 8 HOH 386 1137 607 HOH HOH B . Z 8 HOH 387 1138 608 HOH HOH B . Z 8 HOH 388 1139 612 HOH HOH B . Z 8 HOH 389 1140 613 HOH HOH B . Z 8 HOH 390 1141 614 HOH HOH B . Z 8 HOH 391 1142 619 HOH HOH B . Z 8 HOH 392 1143 620 HOH HOH B . Z 8 HOH 393 1144 626 HOH HOH B . Z 8 HOH 394 1145 627 HOH HOH B . Z 8 HOH 395 1146 632 HOH HOH B . Z 8 HOH 396 1147 633 HOH HOH B . Z 8 HOH 397 1148 634 HOH HOH B . Z 8 HOH 398 1149 635 HOH HOH B . Z 8 HOH 399 1150 637 HOH HOH B . Z 8 HOH 400 1151 638 HOH HOH B . Z 8 HOH 401 1152 641 HOH HOH B . Z 8 HOH 402 1153 643 HOH HOH B . Z 8 HOH 403 1154 644 HOH HOH B . Z 8 HOH 404 1155 652 HOH HOH B . Z 8 HOH 405 1156 653 HOH HOH B . Z 8 HOH 406 1157 654 HOH HOH B . Z 8 HOH 407 1158 655 HOH HOH B . Z 8 HOH 408 1159 658 HOH HOH B . Z 8 HOH 409 1160 659 HOH HOH B . Z 8 HOH 410 1161 663 HOH HOH B . Z 8 HOH 411 1162 664 HOH HOH B . Z 8 HOH 412 1163 665 HOH HOH B . Z 8 HOH 413 1164 666 HOH HOH B . Z 8 HOH 414 1165 667 HOH HOH B . Z 8 HOH 415 1166 668 HOH HOH B . Z 8 HOH 416 1167 670 HOH HOH B . Z 8 HOH 417 1168 676 HOH HOH B . Z 8 HOH 418 1169 681 HOH HOH B . Z 8 HOH 419 1170 684 HOH HOH B . Z 8 HOH 420 1171 685 HOH HOH B . Z 8 HOH 421 1172 686 HOH HOH B . Z 8 HOH 422 1173 687 HOH HOH B . Z 8 HOH 423 1174 688 HOH HOH B . Z 8 HOH 424 1175 689 HOH HOH B . Z 8 HOH 425 1176 690 HOH HOH B . Z 8 HOH 426 1177 697 HOH HOH B . Z 8 HOH 427 1178 698 HOH HOH B . Z 8 HOH 428 1179 700 HOH HOH B . Z 8 HOH 429 1180 701 HOH HOH B . Z 8 HOH 430 1181 703 HOH HOH B . Z 8 HOH 431 1182 706 HOH HOH B . Z 8 HOH 432 1183 707 HOH HOH B . Z 8 HOH 433 1184 713 HOH HOH B . Z 8 HOH 434 1185 715 HOH HOH B . Z 8 HOH 435 1186 717 HOH HOH B . Z 8 HOH 436 1187 720 HOH HOH B . Z 8 HOH 437 1188 724 HOH HOH B . Z 8 HOH 438 1189 725 HOH HOH B . Z 8 HOH 439 1190 726 HOH HOH B . Z 8 HOH 440 1191 727 HOH HOH B . Z 8 HOH 441 1192 729 HOH HOH B . Z 8 HOH 442 1193 731 HOH HOH B . Z 8 HOH 443 1194 733 HOH HOH B . Z 8 HOH 444 1195 738 HOH HOH B . Z 8 HOH 445 1196 739 HOH HOH B . Z 8 HOH 446 1197 742 HOH HOH B . Z 8 HOH 447 1198 743 HOH HOH B . Z 8 HOH 448 1199 744 HOH HOH B . Z 8 HOH 449 1200 745 HOH HOH B . Z 8 HOH 450 1201 746 HOH HOH B . Z 8 HOH 451 1202 748 HOH HOH B . Z 8 HOH 452 1203 749 HOH HOH B . Z 8 HOH 453 1204 750 HOH HOH B . Z 8 HOH 454 1205 751 HOH HOH B . Z 8 HOH 455 1206 802 HOH HOH B . Z 8 HOH 456 1207 803 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 90 A ASN 110 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 518 A ASN 538 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 725 A ASN 745 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 90 B ASN 110 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 518 B ASN 538 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 725 B ASN 745 ? ASN 'GLYCOSYLATION SITE' 7 A TPQ 441 A TPQ 461 ? TYR ? 8 B TPQ 441 B TPQ 461 ? TYR ? # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 22780 ? 1 MORE -92 ? 1 'SSA (A^2)' 46890 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O4 ? A TPQ 441 ? A TPQ 461 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 NE2 ? A HIS 490 ? A HIS 510 ? 1_555 89.8 ? 2 O4 ? A TPQ 441 ? A TPQ 461 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 NE2 ? A HIS 492 ? A HIS 512 ? 1_555 113.0 ? 3 NE2 ? A HIS 490 ? A HIS 510 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 NE2 ? A HIS 492 ? A HIS 512 ? 1_555 97.9 ? 4 O4 ? A TPQ 441 ? A TPQ 461 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 ND1 ? A HIS 655 ? A HIS 675 ? 1_555 103.5 ? 5 NE2 ? A HIS 490 ? A HIS 510 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 ND1 ? A HIS 655 ? A HIS 675 ? 1_555 97.4 ? 6 NE2 ? A HIS 492 ? A HIS 512 ? 1_555 CU ? C CU . ? A CU 801 ? 1_555 ND1 ? A HIS 655 ? A HIS 675 ? 1_555 140.3 ? 7 OD1 ? A ASP 499 ? A ASP 519 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? A LEU 500 ? A LEU 520 ? 1_555 102.3 ? 8 OD1 ? A ASP 499 ? A ASP 519 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 OD1 ? A ASP 501 ? A ASP 521 ? 1_555 87.3 ? 9 O ? A LEU 500 ? A LEU 520 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 OD1 ? A ASP 501 ? A ASP 521 ? 1_555 77.9 ? 10 OD1 ? A ASP 499 ? A ASP 519 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 OD1 ? A ASP 644 ? A ASP 664 ? 1_555 97.0 ? 11 O ? A LEU 500 ? A LEU 520 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 OD1 ? A ASP 644 ? A ASP 664 ? 1_555 157.4 ? 12 OD1 ? A ASP 501 ? A ASP 521 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 OD1 ? A ASP 644 ? A ASP 664 ? 1_555 91.4 ? 13 OD1 ? A ASP 499 ? A ASP 519 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? A LEU 645 ? A LEU 665 ? 1_555 85.6 ? 14 O ? A LEU 500 ? A LEU 520 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? A LEU 645 ? A LEU 665 ? 1_555 91.6 ? 15 OD1 ? A ASP 501 ? A ASP 521 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? A LEU 645 ? A LEU 665 ? 1_555 165.7 ? 16 OD1 ? A ASP 644 ? A ASP 664 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? A LEU 645 ? A LEU 665 ? 1_555 101.8 ? 17 OD1 ? A ASP 499 ? A ASP 519 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? Y HOH . ? A HOH 20 ? 1_555 174.0 ? 18 O ? A LEU 500 ? A LEU 520 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? Y HOH . ? A HOH 20 ? 1_555 71.8 ? 19 OD1 ? A ASP 501 ? A ASP 521 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? Y HOH . ? A HOH 20 ? 1_555 90.9 ? 20 OD1 ? A ASP 644 ? A ASP 664 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? Y HOH . ? A HOH 20 ? 1_555 88.8 ? 21 O ? A LEU 645 ? A LEU 665 ? 1_555 CA ? D CA . ? A CA 802 ? 1_555 O ? Y HOH . ? A HOH 20 ? 1_555 94.9 ? 22 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 51.3 ? 23 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? A PHE 633 ? A PHE 653 ? 1_555 90.2 ? 24 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? A PHE 633 ? A PHE 653 ? 1_555 98.4 ? 25 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 81.9 ? 26 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 131.5 ? 27 O ? A PHE 633 ? A PHE 653 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 92.9 ? 28 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 99.5 ? 29 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 92.0 ? 30 O ? A PHE 633 ? A PHE 653 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 168.8 ? 31 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 83.1 ? 32 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 758 ? 1_555 126.8 ? 33 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 758 ? 1_555 75.5 ? 34 O ? A PHE 633 ? A PHE 653 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 758 ? 1_555 98.2 ? 35 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 758 ? 1_555 148.8 ? 36 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 758 ? 1_555 80.4 ? 37 OE1 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 155.8 ? 38 OE2 ? A GLU 542 ? A GLU 562 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 151.8 ? 39 O ? A PHE 633 ? A PHE 653 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 80.1 ? 40 OD1 ? A ASN 636 ? A ASN 656 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 76.6 ? 41 OE1 ? A GLU 638 ? A GLU 658 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 88.8 ? 42 O ? Y HOH . ? A HOH 758 ? 1_555 CA ? E CA . ? A CA 803 ? 1_555 O ? Y HOH . ? A HOH 817 ? 1_555 76.8 ? 43 O4 ? B TPQ 441 ? B TPQ 461 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 NE2 ? B HIS 490 ? B HIS 510 ? 1_555 89.5 ? 44 O4 ? B TPQ 441 ? B TPQ 461 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 NE2 ? B HIS 492 ? B HIS 512 ? 1_555 111.6 ? 45 NE2 ? B HIS 490 ? B HIS 510 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 NE2 ? B HIS 492 ? B HIS 512 ? 1_555 96.9 ? 46 O4 ? B TPQ 441 ? B TPQ 461 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 ND1 ? B HIS 655 ? B HIS 675 ? 1_555 103.6 ? 47 NE2 ? B HIS 490 ? B HIS 510 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 ND1 ? B HIS 655 ? B HIS 675 ? 1_555 95.7 ? 48 NE2 ? B HIS 492 ? B HIS 512 ? 1_555 CU ? O CU . ? B CU 801 ? 1_555 ND1 ? B HIS 655 ? B HIS 675 ? 1_555 142.6 ? 49 OD1 ? B ASP 499 ? B ASP 519 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? B LEU 500 ? B LEU 520 ? 1_555 101.0 ? 50 OD1 ? B ASP 499 ? B ASP 519 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 OD1 ? B ASP 501 ? B ASP 521 ? 1_555 89.0 ? 51 O ? B LEU 500 ? B LEU 520 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 OD1 ? B ASP 501 ? B ASP 521 ? 1_555 76.7 ? 52 OD1 ? B ASP 499 ? B ASP 519 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 OD1 ? B ASP 644 ? B ASP 664 ? 1_555 100.4 ? 53 O ? B LEU 500 ? B LEU 520 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 OD1 ? B ASP 644 ? B ASP 664 ? 1_555 154.0 ? 54 OD1 ? B ASP 501 ? B ASP 521 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 OD1 ? B ASP 644 ? B ASP 664 ? 1_555 89.1 ? 55 OD1 ? B ASP 499 ? B ASP 519 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? B LEU 645 ? B LEU 665 ? 1_555 87.7 ? 56 O ? B LEU 500 ? B LEU 520 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? B LEU 645 ? B LEU 665 ? 1_555 94.1 ? 57 OD1 ? B ASP 501 ? B ASP 521 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? B LEU 645 ? B LEU 665 ? 1_555 169.5 ? 58 OD1 ? B ASP 644 ? B ASP 664 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? B LEU 645 ? B LEU 665 ? 1_555 101.3 ? 59 OD1 ? B ASP 499 ? B ASP 519 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? Z HOH . ? B HOH 876 ? 1_555 174.6 ? 60 O ? B LEU 500 ? B LEU 520 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? Z HOH . ? B HOH 876 ? 1_555 74.1 ? 61 OD1 ? B ASP 501 ? B ASP 521 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? Z HOH . ? B HOH 876 ? 1_555 87.6 ? 62 OD1 ? B ASP 644 ? B ASP 664 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? Z HOH . ? B HOH 876 ? 1_555 83.8 ? 63 O ? B LEU 645 ? B LEU 665 ? 1_555 CA ? P CA . ? B CA 802 ? 1_555 O ? Z HOH . ? B HOH 876 ? 1_555 94.9 ? 64 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 48.9 ? 65 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? B PHE 633 ? B PHE 653 ? 1_555 92.5 ? 66 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? B PHE 633 ? B PHE 653 ? 1_555 104.9 ? 67 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 82.0 ? 68 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 129.2 ? 69 O ? B PHE 633 ? B PHE 653 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 86.9 ? 70 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 95.7 ? 71 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 80.0 ? 72 O ? B PHE 633 ? B PHE 653 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 171.7 ? 73 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 95.2 ? 74 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 5 ? 1_555 153.0 ? 75 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 5 ? 1_555 157.0 ? 76 O ? B PHE 633 ? B PHE 653 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 5 ? 1_555 74.8 ? 77 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 5 ? 1_555 73.8 ? 78 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 5 ? 1_555 98.1 ? 79 OE1 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 121.7 ? 80 OE2 ? B GLU 542 ? B GLU 562 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 73.1 ? 81 O ? B PHE 633 ? B PHE 653 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 98.7 ? 82 OD1 ? B ASN 636 ? B ASN 656 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 155.0 ? 83 OE1 ? B GLU 638 ? B GLU 658 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 76.1 ? 84 O ? Z HOH . ? B HOH 5 ? 1_555 CA ? Q CA . ? B CA 803 ? 1_555 O ? Z HOH . ? B HOH 834 ? 1_555 84.2 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2009-10-20 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-11-01 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Derived calculations' 2 2 'Structure model' 'Non-polymer description' 3 2 'Structure model' 'Version format compliance' 4 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 DENZO . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data reduction' http://www.hkl-xray.com/ ? ? 2 SCALEPACK . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data scaling' http://www.hkl-xray.com/ ? ? 3 REFMAC . ? program 'Garib N. Murshudov' garib@ysbl.york.ac.uk refinement http://www.ccp4.ac.uk/dist/html/refmac5.html Fortran_77 ? 4 PDB_EXTRACT 3.005 'June 11, 2008' package PDB help@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 5 Blu-Ice . ? ? ? ? 'data collection' ? ? ? 6 HKL-2000 . ? ? ? ? 'data reduction' ? ? ? 7 HKL-2000 . ? ? ? ? 'data scaling' ? ? ? 8 REFMAC 5.5.0063 ? ? ? ? phasing ? ? ? # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS A 178 ? ? -133.92 -65.44 2 1 ARG A 190 ? ? -119.42 73.14 3 1 TYR A 459 ? ? -161.48 -88.29 4 1 VAL A 604 ? ? -102.38 -64.32 5 1 GLN A 610 ? ? 47.85 -110.07 6 1 ASN A 690 ? ? -112.63 50.10 7 1 THR B 62 ? ? -91.58 59.12 8 1 SER B 129 ? ? 37.84 65.10 9 1 HIS B 178 ? ? 56.30 -99.01 10 1 TYR B 319 ? ? -160.01 107.91 11 1 TYR B 459 ? ? -161.77 -85.85 12 1 VAL B 604 ? ? -102.57 -65.94 13 1 GLN B 610 ? ? 48.30 -109.92 14 1 ASN B 657 ? ? 39.63 63.37 15 1 ASN B 690 ? ? -110.76 54.21 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 28 ? CG ? A ARG 8 CG 2 1 Y 1 A ARG 28 ? CD ? A ARG 8 CD 3 1 Y 1 A ARG 28 ? NE ? A ARG 8 NE 4 1 Y 1 A ARG 28 ? CZ ? A ARG 8 CZ 5 1 Y 1 A ARG 28 ? NH1 ? A ARG 8 NH1 6 1 Y 1 A ARG 28 ? NH2 ? A ARG 8 NH2 7 1 Y 1 A GLN 39 ? CG ? A GLN 19 CG 8 1 Y 1 A GLN 39 ? CD ? A GLN 19 CD 9 1 Y 1 A GLN 39 ? OE1 ? A GLN 19 OE1 10 1 Y 1 A GLN 39 ? NE2 ? A GLN 19 NE2 11 1 Y 1 A LYS 52 ? CE ? A LYS 32 CE 12 1 Y 1 A LYS 52 ? NZ ? A LYS 32 NZ 13 1 Y 1 A ARG 55 ? CZ ? A ARG 35 CZ 14 1 Y 1 A ARG 55 ? NH1 ? A ARG 35 NH1 15 1 Y 1 A ARG 55 ? NH2 ? A ARG 35 NH2 16 1 Y 1 A LYS 78 ? NZ ? A LYS 58 NZ 17 1 Y 1 A GLU 90 ? OE1 ? A GLU 70 OE1 18 1 Y 1 A GLU 90 ? OE2 ? A GLU 70 OE2 19 1 Y 1 A ARG 91 ? CG ? A ARG 71 CG 20 1 Y 1 A ARG 91 ? CD ? A ARG 71 CD 21 1 Y 1 A ARG 91 ? NE ? A ARG 71 NE 22 1 Y 1 A ARG 91 ? CZ ? A ARG 71 CZ 23 1 Y 1 A ARG 91 ? NH1 ? A ARG 71 NH1 24 1 Y 1 A ARG 91 ? NH2 ? A ARG 71 NH2 25 1 Y 1 A GLN 135 ? OE1 ? A GLN 115 OE1 26 1 Y 1 A GLN 135 ? NE2 ? A GLN 115 NE2 27 1 Y 1 A TYR 152 ? CD1 ? A TYR 132 CD1 28 1 Y 1 A TYR 152 ? CD2 ? A TYR 132 CD2 29 1 Y 1 A TYR 152 ? CE1 ? A TYR 132 CE1 30 1 Y 1 A TYR 152 ? CE2 ? A TYR 132 CE2 31 1 Y 1 A TYR 152 ? CZ ? A TYR 132 CZ 32 1 Y 1 A TYR 152 ? OH ? A TYR 132 OH 33 1 Y 1 A LYS 241 ? CE ? A LYS 221 CE 34 1 Y 1 A LYS 241 ? NZ ? A LYS 221 NZ 35 1 Y 1 A GLU 247 ? CG ? A GLU 227 CG 36 1 Y 1 A GLU 247 ? CD ? A GLU 227 CD 37 1 Y 1 A GLU 247 ? OE1 ? A GLU 227 OE1 38 1 Y 1 A GLU 247 ? OE2 ? A GLU 227 OE2 39 1 Y 1 A ARG 251 ? CG ? A ARG 231 CG 40 1 Y 1 A ARG 251 ? CD ? A ARG 231 CD 41 1 Y 1 A ARG 251 ? NE ? A ARG 231 NE 42 1 Y 1 A ARG 251 ? CZ ? A ARG 231 CZ 43 1 Y 1 A ARG 251 ? NH1 ? A ARG 231 NH1 44 1 Y 1 A ARG 251 ? NH2 ? A ARG 231 NH2 45 1 Y 1 A LYS 252 ? CE ? A LYS 232 CE 46 1 Y 1 A LYS 252 ? NZ ? A LYS 232 NZ 47 1 Y 1 A ASP 259 ? CG ? A ASP 239 CG 48 1 Y 1 A ASP 259 ? OD1 ? A ASP 239 OD1 49 1 Y 1 A ASP 259 ? OD2 ? A ASP 239 OD2 50 1 Y 1 A GLU 264 ? CG ? A GLU 244 CG 51 1 Y 1 A GLU 264 ? CD ? A GLU 244 CD 52 1 Y 1 A GLU 264 ? OE1 ? A GLU 244 OE1 53 1 Y 1 A GLU 264 ? OE2 ? A GLU 244 OE2 54 1 Y 1 A GLU 278 ? CG ? A GLU 258 CG 55 1 Y 1 A GLU 278 ? CD ? A GLU 258 CD 56 1 Y 1 A GLU 278 ? OE1 ? A GLU 258 OE1 57 1 Y 1 A GLU 278 ? OE2 ? A GLU 258 OE2 58 1 Y 1 A SER 293 ? OG ? A SER 273 OG 59 1 Y 1 A HIS 296 ? CG ? A HIS 276 CG 60 1 Y 1 A HIS 296 ? ND1 ? A HIS 276 ND1 61 1 Y 1 A HIS 296 ? CD2 ? A HIS 276 CD2 62 1 Y 1 A HIS 296 ? CE1 ? A HIS 276 CE1 63 1 Y 1 A HIS 296 ? NE2 ? A HIS 276 NE2 64 1 Y 1 A ARG 301 ? CG ? A ARG 281 CG 65 1 Y 1 A ARG 301 ? CD ? A ARG 281 CD 66 1 Y 1 A ARG 301 ? NE ? A ARG 281 NE 67 1 Y 1 A ARG 301 ? CZ ? A ARG 281 CZ 68 1 Y 1 A ARG 301 ? NH1 ? A ARG 281 NH1 69 1 Y 1 A ARG 301 ? NH2 ? A ARG 281 NH2 70 1 Y 1 A LYS 436 ? CG ? A LYS 416 CG 71 1 Y 1 A LYS 436 ? CD ? A LYS 416 CD 72 1 Y 1 A LYS 436 ? CE ? A LYS 416 CE 73 1 Y 1 A LYS 436 ? NZ ? A LYS 416 NZ 74 1 Y 1 A VAL 458 ? CG1 ? A VAL 438 CG1 75 1 Y 1 A VAL 458 ? CG2 ? A VAL 438 CG2 76 1 Y 1 A GLN 533 ? CG ? A GLN 513 CG 77 1 Y 1 A GLN 533 ? CD ? A GLN 513 CD 78 1 Y 1 A GLN 533 ? OE1 ? A GLN 513 OE1 79 1 Y 1 A GLN 533 ? NE2 ? A GLN 513 NE2 80 1 Y 1 A LYS 535 ? CE ? A LYS 515 CE 81 1 Y 1 A LYS 535 ? NZ ? A LYS 515 NZ 82 1 Y 1 A ARG 546 ? NE ? A ARG 526 NE 83 1 Y 1 A ARG 546 ? CZ ? A ARG 526 CZ 84 1 Y 1 A ARG 546 ? NH1 ? A ARG 526 NH1 85 1 Y 1 A ARG 546 ? NH2 ? A ARG 526 NH2 86 1 Y 1 A ARG 568 ? NE ? A ARG 548 NE 87 1 Y 1 A ARG 568 ? CZ ? A ARG 548 CZ 88 1 Y 1 A ARG 568 ? NH1 ? A ARG 548 NH1 89 1 Y 1 A ARG 568 ? NH2 ? A ARG 548 NH2 90 1 Y 1 A LYS 570 ? CG ? A LYS 550 CG 91 1 Y 1 A LYS 570 ? CD ? A LYS 550 CD 92 1 Y 1 A LYS 570 ? CE ? A LYS 550 CE 93 1 Y 1 A LYS 570 ? NZ ? A LYS 550 NZ 94 1 Y 1 A LYS 572 ? CG ? A LYS 552 CG 95 1 Y 1 A LYS 572 ? CD ? A LYS 552 CD 96 1 Y 1 A LYS 572 ? CE ? A LYS 552 CE 97 1 Y 1 A LYS 572 ? NZ ? A LYS 552 NZ 98 1 Y 1 A LYS 575 ? CD ? A LYS 555 CD 99 1 Y 1 A LYS 575 ? CE ? A LYS 555 CE 100 1 Y 1 A LYS 575 ? NZ ? A LYS 555 NZ 101 1 Y 1 A LYS 590 ? CD ? A LYS 570 CD 102 1 Y 1 A LYS 590 ? CE ? A LYS 570 CE 103 1 Y 1 A LYS 590 ? NZ ? A LYS 570 NZ 104 1 Y 1 B ARG 28 ? CG ? B ARG 8 CG 105 1 Y 1 B ARG 28 ? CD ? B ARG 8 CD 106 1 Y 1 B ARG 28 ? NE ? B ARG 8 NE 107 1 Y 1 B ARG 28 ? CZ ? B ARG 8 CZ 108 1 Y 1 B ARG 28 ? NH1 ? B ARG 8 NH1 109 1 Y 1 B ARG 28 ? NH2 ? B ARG 8 NH2 110 1 Y 1 B GLN 39 ? CG ? B GLN 19 CG 111 1 Y 1 B GLN 39 ? CD ? B GLN 19 CD 112 1 Y 1 B GLN 39 ? OE1 ? B GLN 19 OE1 113 1 Y 1 B GLN 39 ? NE2 ? B GLN 19 NE2 114 1 Y 1 B LYS 52 ? CG ? B LYS 32 CG 115 1 Y 1 B LYS 52 ? CD ? B LYS 32 CD 116 1 Y 1 B LYS 52 ? CE ? B LYS 32 CE 117 1 Y 1 B LYS 52 ? NZ ? B LYS 32 NZ 118 1 Y 1 B ARG 55 ? NH1 ? B ARG 35 NH1 119 1 Y 1 B ARG 55 ? NH2 ? B ARG 35 NH2 120 1 Y 1 B ARG 84 ? NE ? B ARG 64 NE 121 1 Y 1 B ARG 84 ? CZ ? B ARG 64 CZ 122 1 Y 1 B ARG 84 ? NH1 ? B ARG 64 NH1 123 1 Y 1 B ARG 84 ? NH2 ? B ARG 64 NH2 124 1 Y 1 B LYS 88 ? CE ? B LYS 68 CE 125 1 Y 1 B LYS 88 ? NZ ? B LYS 68 NZ 126 1 Y 1 B ARG 91 ? CG ? B ARG 71 CG 127 1 Y 1 B ARG 91 ? CD ? B ARG 71 CD 128 1 Y 1 B ARG 91 ? NE ? B ARG 71 NE 129 1 Y 1 B ARG 91 ? CZ ? B ARG 71 CZ 130 1 Y 1 B ARG 91 ? NH1 ? B ARG 71 NH1 131 1 Y 1 B ARG 91 ? NH2 ? B ARG 71 NH2 132 1 Y 1 B GLU 107 ? CG ? B GLU 87 CG 133 1 Y 1 B GLU 107 ? CD ? B GLU 87 CD 134 1 Y 1 B GLU 107 ? OE1 ? B GLU 87 OE1 135 1 Y 1 B GLU 107 ? OE2 ? B GLU 87 OE2 136 1 Y 1 B ARG 126 ? CG ? B ARG 106 CG 137 1 Y 1 B ARG 126 ? CD ? B ARG 106 CD 138 1 Y 1 B ARG 126 ? NE ? B ARG 106 NE 139 1 Y 1 B ARG 126 ? CZ ? B ARG 106 CZ 140 1 Y 1 B ARG 126 ? NH1 ? B ARG 106 NH1 141 1 Y 1 B ARG 126 ? NH2 ? B ARG 106 NH2 142 1 Y 1 B SER 129 ? OG ? B SER 109 OG 143 1 Y 1 B GLN 156 ? CG ? B GLN 136 CG 144 1 Y 1 B GLN 156 ? CD ? B GLN 136 CD 145 1 Y 1 B GLN 156 ? OE1 ? B GLN 136 OE1 146 1 Y 1 B GLN 156 ? NE2 ? B GLN 136 NE2 147 1 Y 1 B GLN 164 ? CG ? B GLN 144 CG 148 1 Y 1 B GLN 164 ? CD ? B GLN 144 CD 149 1 Y 1 B GLN 164 ? OE1 ? B GLN 144 OE1 150 1 Y 1 B GLN 164 ? NE2 ? B GLN 144 NE2 151 1 Y 1 B GLU 247 ? CG ? B GLU 227 CG 152 1 Y 1 B GLU 247 ? CD ? B GLU 227 CD 153 1 Y 1 B GLU 247 ? OE1 ? B GLU 227 OE1 154 1 Y 1 B GLU 247 ? OE2 ? B GLU 227 OE2 155 1 Y 1 B ARG 251 ? CG ? B ARG 231 CG 156 1 Y 1 B ARG 251 ? CD ? B ARG 231 CD 157 1 Y 1 B ARG 251 ? NE ? B ARG 231 NE 158 1 Y 1 B ARG 251 ? CZ ? B ARG 231 CZ 159 1 Y 1 B ARG 251 ? NH1 ? B ARG 231 NH1 160 1 Y 1 B ARG 251 ? NH2 ? B ARG 231 NH2 161 1 Y 1 B GLU 278 ? CG ? B GLU 258 CG 162 1 Y 1 B GLU 278 ? CD ? B GLU 258 CD 163 1 Y 1 B GLU 278 ? OE1 ? B GLU 258 OE1 164 1 Y 1 B GLU 278 ? OE2 ? B GLU 258 OE2 165 1 Y 1 B ARG 311 ? CG ? B ARG 291 CG 166 1 Y 1 B ARG 311 ? CD ? B ARG 291 CD 167 1 Y 1 B ARG 311 ? NE ? B ARG 291 NE 168 1 Y 1 B ARG 311 ? CZ ? B ARG 291 CZ 169 1 Y 1 B ARG 311 ? NH1 ? B ARG 291 NH1 170 1 Y 1 B ARG 311 ? NH2 ? B ARG 291 NH2 171 1 Y 1 B GLU 313 ? CG ? B GLU 293 CG 172 1 Y 1 B GLU 313 ? CD ? B GLU 293 CD 173 1 Y 1 B GLU 313 ? OE1 ? B GLU 293 OE1 174 1 Y 1 B GLU 313 ? OE2 ? B GLU 293 OE2 175 1 Y 1 B VAL 458 ? CG1 ? B VAL 438 CG1 176 1 Y 1 B VAL 458 ? CG2 ? B VAL 438 CG2 177 1 Y 1 B GLN 533 ? CG ? B GLN 513 CG 178 1 Y 1 B GLN 533 ? CD ? B GLN 513 CD 179 1 Y 1 B GLN 533 ? OE1 ? B GLN 513 OE1 180 1 Y 1 B GLN 533 ? NE2 ? B GLN 513 NE2 181 1 Y 1 B LYS 535 ? CD ? B LYS 515 CD 182 1 Y 1 B LYS 535 ? CE ? B LYS 515 CE 183 1 Y 1 B LYS 535 ? NZ ? B LYS 515 NZ 184 1 Y 1 B ARG 546 ? NE ? B ARG 526 NE 185 1 Y 1 B ARG 546 ? CZ ? B ARG 526 CZ 186 1 Y 1 B ARG 546 ? NH1 ? B ARG 526 NH1 187 1 Y 1 B ARG 546 ? NH2 ? B ARG 526 NH2 188 1 Y 1 B GLN 556 ? CG ? B GLN 536 CG 189 1 Y 1 B GLN 556 ? CD ? B GLN 536 CD 190 1 Y 1 B GLN 556 ? OE1 ? B GLN 536 OE1 191 1 Y 1 B GLN 556 ? NE2 ? B GLN 536 NE2 192 1 Y 1 B ARG 568 ? CZ ? B ARG 548 CZ 193 1 Y 1 B ARG 568 ? NH1 ? B ARG 548 NH1 194 1 Y 1 B ARG 568 ? NH2 ? B ARG 548 NH2 195 1 Y 1 B LYS 570 ? CG ? B LYS 550 CG 196 1 Y 1 B LYS 570 ? CD ? B LYS 550 CD 197 1 Y 1 B LYS 570 ? CE ? B LYS 550 CE 198 1 Y 1 B LYS 570 ? NZ ? B LYS 550 NZ 199 1 Y 1 B LYS 572 ? CG ? B LYS 552 CG 200 1 Y 1 B LYS 572 ? CD ? B LYS 552 CD 201 1 Y 1 B LYS 572 ? CE ? B LYS 552 CE 202 1 Y 1 B LYS 572 ? NZ ? B LYS 552 NZ 203 1 Y 1 B LYS 590 ? CE ? B LYS 570 CE 204 1 Y 1 B LYS 590 ? NZ ? B LYS 570 NZ 205 1 Y 1 B ASN 721 ? CG ? B ASN 701 CG 206 1 Y 1 B ASN 721 ? OD1 ? B ASN 701 OD1 207 1 Y 1 B ASN 721 ? ND2 ? B ASN 701 ND2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 21 ? A ARG 1 2 1 Y 1 A SER 22 ? A SER 2 3 1 Y 1 A PRO 23 ? A PRO 3 4 1 Y 1 A GLY 24 ? A GLY 4 5 1 Y 1 A THR 25 ? A THR 5 6 1 Y 1 A LEU 26 ? A LEU 6 7 1 Y 1 A PRO 268 ? A PRO 248 8 1 Y 1 A GLY 269 ? A GLY 249 9 1 Y 1 A GLY 270 ? A GLY 250 10 1 Y 1 A LYS 271 ? A LYS 251 11 1 Y 1 A GLY 272 ? A GLY 252 12 1 Y 1 A HIS 273 ? A HIS 253 13 1 Y 1 A ASP 274 ? A ASP 254 14 1 Y 1 A SER 275 ? A SER 255 15 1 Y 1 A THR 276 ? A THR 256 16 1 Y 1 A GLU 277 ? A GLU 257 17 1 Y 1 B ARG 21 ? B ARG 1 18 1 Y 1 B SER 22 ? B SER 2 19 1 Y 1 B PRO 23 ? B PRO 3 20 1 Y 1 B GLY 24 ? B GLY 4 21 1 Y 1 B THR 25 ? B THR 5 22 1 Y 1 B LEU 26 ? B LEU 6 23 1 Y 1 B PRO 27 ? B PRO 7 24 1 Y 1 B GLU 264 ? B GLU 244 25 1 Y 1 B ASP 265 ? B ASP 245 26 1 Y 1 B PRO 266 ? B PRO 246 27 1 Y 1 B LEU 267 ? B LEU 247 28 1 Y 1 B PRO 268 ? B PRO 248 29 1 Y 1 B GLY 269 ? B GLY 249 30 1 Y 1 B GLY 270 ? B GLY 250 31 1 Y 1 B LYS 271 ? B LYS 251 32 1 Y 1 B GLY 272 ? B GLY 252 33 1 Y 1 B HIS 273 ? B HIS 253 34 1 Y 1 B ASP 274 ? B ASP 254 35 1 Y 1 B SER 275 ? B SER 255 36 1 Y 1 B THR 276 ? B THR 256 37 1 Y 1 B GLU 277 ? B GLU 257 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'COPPER (II) ION' CU 3 'CALCIUM ION' CA 4 GLYCEROL GOL 5 '1,5-BIS(4-AMIDINOPHENOXY)PENTANE' PNT 6 N-ACETYL-D-GLUCOSAMINE NAG 7 BETA-D-MANNOSE BMA 8 water HOH #