data_3GDP # _entry.id 3GDP # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3GDP RCSB RCSB051731 WWPDB D_1000051731 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1ju2 'triclinic crystal form' unspecified PDB 3gdn 'complex with benzaldehyde' unspecified # _pdbx_database_status.entry_id 3GDP _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2009-02-24 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Dreveny, I.' 1 'Gruber, K.' 2 'Kratky, C.' 3 # _citation.id primary _citation.title ;Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. ; _citation.journal_abbrev Biochemistry _citation.journal_volume 48 _citation.page_first 3370 _citation.page_last 3377 _citation.year 2009 _citation.journal_id_ASTM BICHAW _citation.country US _citation.journal_id_ISSN 0006-2960 _citation.journal_id_CSD 0033 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 19256550 _citation.pdbx_database_id_DOI 10.1021/bi802162s # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Dreveny, I.' 1 primary 'Andryushkova, A.S.' 2 primary 'Glieder, A.' 3 primary 'Gruber, K.' 4 primary 'Kratky, C.' 5 # _cell.entry_id 3GDP _cell.length_a 69.050 _cell.length_b 93.710 _cell.length_c 87.260 _cell.angle_alpha 90.00 _cell.angle_beta 106.39 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 3GDP _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'R-oxynitrile lyase isoenzyme 1' 56535.785 2 4.1.2.10 ? ? ? 2 non-polymer syn 'ISOPROPYL ALCOHOL' 60.095 2 ? ? ? ? 3 non-polymer syn 'FLAVIN-ADENINE DINUCLEOTIDE' 785.550 2 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 11 ? ? ? ? 5 non-polymer man BETA-L-FUCOSE 164.156 1 ? ? ? ? 6 non-polymer man ALPHA-D-MANNOSE 180.156 4 ? ? ? ? 7 non-polymer man ALPHA-L-FUCOSE 164.156 2 ? ? ? ? 8 non-polymer man BETA-D-MANNOSE 180.156 2 ? ? ? ? 9 non-polymer man '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' 221.208 1 ? ? ? ? 10 water nat water 18.015 1589 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;LATTSDHDFSYLSFAYDATDLELEGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQED DGKTPVERFVSEDGIDNVRGRVLGGTSIINAGVYARANTSIYSASGVDWDMDLVNQTYEWVEDTIVYKPNSQSWQSVTKT AFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFSNAPGLTATGVIYRDSNG TPHQAFVRSKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGQFLHDNPRNFINILPPNPIEPTIVTVLG ISNDFYQCSFSSLPFTTPPFGFFPSSSYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNLTDLSHCV SGMKKIGELLSTDALKPYKVEDLPGVEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGIN ALRVVDGSTFPYTPASHPQGFYLMLGRYVGIKILQERSASD ; _entity_poly.pdbx_seq_one_letter_code_can ;LATTSDHDFSYLSFAYDATDLELEGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQED DGKTPVERFVSEDGIDNVRGRVLGGTSIINAGVYARANTSIYSASGVDWDMDLVNQTYEWVEDTIVYKPNSQSWQSVTKT AFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFSNAPGLTATGVIYRDSNG TPHQAFVRSKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGQFLHDNPRNFINILPPNPIEPTIVTVLG ISNDFYQCSFSSLPFTTPPFGFFPSSSYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNLTDLSHCV SGMKKIGELLSTDALKPYKVEDLPGVEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGIN ALRVVDGSTFPYTPASHPQGFYLMLGRYVGIKILQERSASD ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 LEU n 1 2 ALA n 1 3 THR n 1 4 THR n 1 5 SER n 1 6 ASP n 1 7 HIS n 1 8 ASP n 1 9 PHE n 1 10 SER n 1 11 TYR n 1 12 LEU n 1 13 SER n 1 14 PHE n 1 15 ALA n 1 16 TYR n 1 17 ASP n 1 18 ALA n 1 19 THR n 1 20 ASP n 1 21 LEU n 1 22 GLU n 1 23 LEU n 1 24 GLU n 1 25 GLY n 1 26 SER n 1 27 TYR n 1 28 ASP n 1 29 TYR n 1 30 VAL n 1 31 ILE n 1 32 VAL n 1 33 GLY n 1 34 GLY n 1 35 GLY n 1 36 THR n 1 37 SER n 1 38 GLY n 1 39 CYS n 1 40 PRO n 1 41 LEU n 1 42 ALA n 1 43 ALA n 1 44 THR n 1 45 LEU n 1 46 SER n 1 47 GLU n 1 48 LYS n 1 49 TYR n 1 50 LYS n 1 51 VAL n 1 52 LEU n 1 53 VAL n 1 54 LEU n 1 55 GLU n 1 56 ARG n 1 57 GLY n 1 58 SER n 1 59 LEU n 1 60 PRO n 1 61 THR n 1 62 ALA n 1 63 TYR n 1 64 PRO n 1 65 ASN n 1 66 VAL n 1 67 LEU n 1 68 THR n 1 69 ALA n 1 70 ASP n 1 71 GLY n 1 72 PHE n 1 73 VAL n 1 74 TYR n 1 75 ASN n 1 76 LEU n 1 77 GLN n 1 78 GLN n 1 79 GLU n 1 80 ASP n 1 81 ASP n 1 82 GLY n 1 83 LYS n 1 84 THR n 1 85 PRO n 1 86 VAL n 1 87 GLU n 1 88 ARG n 1 89 PHE n 1 90 VAL n 1 91 SER n 1 92 GLU n 1 93 ASP n 1 94 GLY n 1 95 ILE n 1 96 ASP n 1 97 ASN n 1 98 VAL n 1 99 ARG n 1 100 GLY n 1 101 ARG n 1 102 VAL n 1 103 LEU n 1 104 GLY n 1 105 GLY n 1 106 THR n 1 107 SER n 1 108 ILE n 1 109 ILE n 1 110 ASN n 1 111 ALA n 1 112 GLY n 1 113 VAL n 1 114 TYR n 1 115 ALA n 1 116 ARG n 1 117 ALA n 1 118 ASN n 1 119 THR n 1 120 SER n 1 121 ILE n 1 122 TYR n 1 123 SER n 1 124 ALA n 1 125 SER n 1 126 GLY n 1 127 VAL n 1 128 ASP n 1 129 TRP n 1 130 ASP n 1 131 MET n 1 132 ASP n 1 133 LEU n 1 134 VAL n 1 135 ASN n 1 136 GLN n 1 137 THR n 1 138 TYR n 1 139 GLU n 1 140 TRP n 1 141 VAL n 1 142 GLU n 1 143 ASP n 1 144 THR n 1 145 ILE n 1 146 VAL n 1 147 TYR n 1 148 LYS n 1 149 PRO n 1 150 ASN n 1 151 SER n 1 152 GLN n 1 153 SER n 1 154 TRP n 1 155 GLN n 1 156 SER n 1 157 VAL n 1 158 THR n 1 159 LYS n 1 160 THR n 1 161 ALA n 1 162 PHE n 1 163 LEU n 1 164 GLU n 1 165 ALA n 1 166 GLY n 1 167 VAL n 1 168 HIS n 1 169 PRO n 1 170 ASN n 1 171 HIS n 1 172 GLY n 1 173 PHE n 1 174 SER n 1 175 LEU n 1 176 ASP n 1 177 HIS n 1 178 GLU n 1 179 GLU n 1 180 GLY n 1 181 THR n 1 182 ARG n 1 183 ILE n 1 184 THR n 1 185 GLY n 1 186 SER n 1 187 THR n 1 188 PHE n 1 189 ASP n 1 190 ASN n 1 191 LYS n 1 192 GLY n 1 193 THR n 1 194 ARG n 1 195 HIS n 1 196 ALA n 1 197 ALA n 1 198 ASP n 1 199 GLU n 1 200 LEU n 1 201 LEU n 1 202 ASN n 1 203 LYS n 1 204 GLY n 1 205 ASN n 1 206 SER n 1 207 ASN n 1 208 ASN n 1 209 LEU n 1 210 ARG n 1 211 VAL n 1 212 GLY n 1 213 VAL n 1 214 HIS n 1 215 ALA n 1 216 SER n 1 217 VAL n 1 218 GLU n 1 219 LYS n 1 220 ILE n 1 221 ILE n 1 222 PHE n 1 223 SER n 1 224 ASN n 1 225 ALA n 1 226 PRO n 1 227 GLY n 1 228 LEU n 1 229 THR n 1 230 ALA n 1 231 THR n 1 232 GLY n 1 233 VAL n 1 234 ILE n 1 235 TYR n 1 236 ARG n 1 237 ASP n 1 238 SER n 1 239 ASN n 1 240 GLY n 1 241 THR n 1 242 PRO n 1 243 HIS n 1 244 GLN n 1 245 ALA n 1 246 PHE n 1 247 VAL n 1 248 ARG n 1 249 SER n 1 250 LYS n 1 251 GLY n 1 252 GLU n 1 253 VAL n 1 254 ILE n 1 255 VAL n 1 256 SER n 1 257 ALA n 1 258 GLY n 1 259 THR n 1 260 ILE n 1 261 GLY n 1 262 THR n 1 263 PRO n 1 264 GLN n 1 265 LEU n 1 266 LEU n 1 267 LEU n 1 268 LEU n 1 269 SER n 1 270 GLY n 1 271 VAL n 1 272 GLY n 1 273 PRO n 1 274 GLU n 1 275 SER n 1 276 TYR n 1 277 LEU n 1 278 SER n 1 279 SER n 1 280 LEU n 1 281 ASN n 1 282 ILE n 1 283 PRO n 1 284 VAL n 1 285 VAL n 1 286 LEU n 1 287 SER n 1 288 HIS n 1 289 PRO n 1 290 TYR n 1 291 VAL n 1 292 GLY n 1 293 GLN n 1 294 PHE n 1 295 LEU n 1 296 HIS n 1 297 ASP n 1 298 ASN n 1 299 PRO n 1 300 ARG n 1 301 ASN n 1 302 PHE n 1 303 ILE n 1 304 ASN n 1 305 ILE n 1 306 LEU n 1 307 PRO n 1 308 PRO n 1 309 ASN n 1 310 PRO n 1 311 ILE n 1 312 GLU n 1 313 PRO n 1 314 THR n 1 315 ILE n 1 316 VAL n 1 317 THR n 1 318 VAL n 1 319 LEU n 1 320 GLY n 1 321 ILE n 1 322 SER n 1 323 ASN n 1 324 ASP n 1 325 PHE n 1 326 TYR n 1 327 GLN n 1 328 CYS n 1 329 SER n 1 330 PHE n 1 331 SER n 1 332 SER n 1 333 LEU n 1 334 PRO n 1 335 PHE n 1 336 THR n 1 337 THR n 1 338 PRO n 1 339 PRO n 1 340 PHE n 1 341 GLY n 1 342 PHE n 1 343 PHE n 1 344 PRO n 1 345 SER n 1 346 SER n 1 347 SER n 1 348 TYR n 1 349 PRO n 1 350 LEU n 1 351 PRO n 1 352 ASN n 1 353 SER n 1 354 THR n 1 355 PHE n 1 356 ALA n 1 357 HIS n 1 358 PHE n 1 359 ALA n 1 360 SER n 1 361 LYS n 1 362 VAL n 1 363 ALA n 1 364 GLY n 1 365 PRO n 1 366 LEU n 1 367 SER n 1 368 TYR n 1 369 GLY n 1 370 SER n 1 371 LEU n 1 372 THR n 1 373 LEU n 1 374 LYS n 1 375 SER n 1 376 SER n 1 377 SER n 1 378 ASN n 1 379 VAL n 1 380 ARG n 1 381 VAL n 1 382 SER n 1 383 PRO n 1 384 ASN n 1 385 VAL n 1 386 LYS n 1 387 PHE n 1 388 ASN n 1 389 TYR n 1 390 TYR n 1 391 SER n 1 392 ASN n 1 393 LEU n 1 394 THR n 1 395 ASP n 1 396 LEU n 1 397 SER n 1 398 HIS n 1 399 CYS n 1 400 VAL n 1 401 SER n 1 402 GLY n 1 403 MET n 1 404 LYS n 1 405 LYS n 1 406 ILE n 1 407 GLY n 1 408 GLU n 1 409 LEU n 1 410 LEU n 1 411 SER n 1 412 THR n 1 413 ASP n 1 414 ALA n 1 415 LEU n 1 416 LYS n 1 417 PRO n 1 418 TYR n 1 419 LYS n 1 420 VAL n 1 421 GLU n 1 422 ASP n 1 423 LEU n 1 424 PRO n 1 425 GLY n 1 426 VAL n 1 427 GLU n 1 428 GLY n 1 429 PHE n 1 430 ASN n 1 431 ILE n 1 432 LEU n 1 433 GLY n 1 434 ILE n 1 435 PRO n 1 436 LEU n 1 437 PRO n 1 438 LYS n 1 439 ASP n 1 440 GLN n 1 441 THR n 1 442 ASP n 1 443 ASP n 1 444 ALA n 1 445 ALA n 1 446 PHE n 1 447 GLU n 1 448 THR n 1 449 PHE n 1 450 CYS n 1 451 ARG n 1 452 GLU n 1 453 SER n 1 454 VAL n 1 455 ALA n 1 456 SER n 1 457 TYR n 1 458 TRP n 1 459 HIS n 1 460 TYR n 1 461 HIS n 1 462 GLY n 1 463 GLY n 1 464 CYS n 1 465 LEU n 1 466 VAL n 1 467 GLY n 1 468 LYS n 1 469 VAL n 1 470 LEU n 1 471 ASP n 1 472 GLY n 1 473 ASP n 1 474 PHE n 1 475 ARG n 1 476 VAL n 1 477 THR n 1 478 GLY n 1 479 ILE n 1 480 ASN n 1 481 ALA n 1 482 LEU n 1 483 ARG n 1 484 VAL n 1 485 VAL n 1 486 ASP n 1 487 GLY n 1 488 SER n 1 489 THR n 1 490 PHE n 1 491 PRO n 1 492 TYR n 1 493 THR n 1 494 PRO n 1 495 ALA n 1 496 SER n 1 497 HIS n 1 498 PRO n 1 499 GLN n 1 500 GLY n 1 501 PHE n 1 502 TYR n 1 503 LEU n 1 504 MET n 1 505 LEU n 1 506 GLY n 1 507 ARG n 1 508 TYR n 1 509 VAL n 1 510 GLY n 1 511 ILE n 1 512 LYS n 1 513 ILE n 1 514 LEU n 1 515 GLN n 1 516 GLU n 1 517 ARG n 1 518 SER n 1 519 ALA n 1 520 SER n 1 521 ASP n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'sweet almond' _entity_src_nat.pdbx_organism_scientific 'Prunus dulcis' _entity_src_nat.pdbx_ncbi_taxonomy_id 3755 _entity_src_nat.genus ? _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q945K2_PRUDU _struct_ref.pdbx_db_accession Q945K2 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;LATTSDHDFSYLSFAYDATDLELEGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQED DGKTPVERFVSEDGIDNVRGRVLGGTSIINAGVYARANTSIYSASGVDWDMDLVNQTYEWVEDTIVYKPNSQSWQSVTKT AFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFSNAPGLTATGVIYRDSNG TPHQAFVRSKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGQFLHDNPRNFINILPPNPIEPTIVTVLG ISNDFYQCSFSSLPFTTPPFGFFPSASYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNLTDLSHCV SGMKKIGELLSTDALKPYKVEDLPGVEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGIN ALRVVDGSTFPYTPASHPQGFYLMLGRYVGIKILQERSASD ; _struct_ref.pdbx_align_begin 28 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3GDP A 1 ? 521 ? Q945K2 28 ? 548 ? 1 521 2 1 3GDP B 1 ? 521 ? Q945K2 28 ? 548 ? 1 521 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3GDP SER A 346 ? UNP Q945K2 ALA 373 'SEE REMARK 999' 346 1 2 3GDP SER B 346 ? UNP Q945K2 ALA 373 'SEE REMARK 999' 346 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FAD non-polymer . 'FLAVIN-ADENINE DINUCLEOTIDE' ? 'C27 H33 N9 O15 P2' 785.550 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 FUL L-saccharide . BETA-L-FUCOSE 6-DEOXY-BETA-L-GALACTOSE 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 IPA non-polymer . 'ISOPROPYL ALCOHOL' 2-PROPANOL 'C3 H8 O' 60.095 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NDG D-saccharide . '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3GDP _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.40 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 48.65 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION' _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details '20% w/v PEG-4000, 16% v/v isopropanol, pH 7.0, VAPOR DIFFUSION, temperature 298K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'MAR scanner 345 mm plate' _diffrn_detector.pdbx_collection_date 2001-06-01 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.8439 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'EMBL/DESY, HAMBURG BEAMLINE X11' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.8439 _diffrn_source.pdbx_synchrotron_site 'EMBL/DESY, Hamburg' _diffrn_source.pdbx_synchrotron_beamline X11 # _reflns.entry_id 3GDP _reflns.B_iso_Wilson_estimate 15.300 _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.d_resolution_high 1.57 _reflns.d_resolution_low 39.0 _reflns.number_all 143518 _reflns.number_obs 143518 _reflns.percent_possible_obs 96.7 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value 0.058 _reflns.pdbx_netI_over_sigmaI 11.2 _reflns.pdbx_redundancy 3.4 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.57 _reflns_shell.d_res_low 1.67 _reflns_shell.percent_possible_obs ? _reflns_shell.percent_possible_all 89.9 _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_obs 2.6 _reflns_shell.pdbx_Rsym_value 0.385 _reflns_shell.pdbx_redundancy ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3GDP _refine.ls_d_res_high 1.570 _refine.ls_d_res_low 38.250 _refine.pdbx_ls_sigma_F 0.00 _refine.pdbx_data_cutoff_high_absF 2001043.000 _refine.pdbx_data_cutoff_low_absF 0.000 _refine.ls_percent_reflns_obs 95.600 _refine.ls_number_reflns_obs 142082 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.details 'BULK SOLVENT MODEL USED' _refine.ls_R_factor_R_work 0.186 _refine.ls_R_factor_R_free 0.210 _refine.ls_percent_reflns_R_free 10.000 _refine.ls_number_reflns_R_free 14166 _refine.ls_R_factor_R_free_error 0.002 _refine.B_iso_mean 15.642 _refine.solvent_model_param_bsol 46.627 _refine.solvent_model_param_ksol 0.350 _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.aniso_B[1][1] -1.250 _refine.aniso_B[2][2] 4.900 _refine.aniso_B[3][3] -3.660 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 1.130 _refine.aniso_B[2][3] 0.000 _refine.solvent_model_details 'FLAT MODEL' _refine.pdbx_method_to_determine_struct ? _refine.B_iso_max 53.42 _refine.B_iso_min 4.39 _refine.occupancy_max 1.00 _refine.occupancy_min 0.50 _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all ? _refine.ls_R_factor_all ? _refine.ls_R_factor_obs ? _refine.ls_redundancy_reflns_obs ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_starting_model 'pdb entry 1ju2' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_overall_ESU_R ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 3GDP _refine_analyze.Luzzati_coordinate_error_obs 0.170 _refine_analyze.Luzzati_sigma_a_obs 0.160 _refine_analyze.Luzzati_d_res_low_obs 5.000 _refine_analyze.Luzzati_coordinate_error_free 0.200 _refine_analyze.Luzzati_sigma_a_free 0.170 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7988 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 378 _refine_hist.number_atoms_solvent 1589 _refine_hist.number_atoms_total 9955 _refine_hist.d_res_high 1.570 _refine_hist.d_res_low 38.250 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d ? 0.006 ? ? 'X-RAY DIFFRACTION' ? c_angle_deg ? 1.400 ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d ? 24.400 ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d ? 0.870 ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it ? 0.950 1.500 ? 'X-RAY DIFFRACTION' ? c_mcangle_it ? 1.370 2.000 ? 'X-RAY DIFFRACTION' ? c_scbond_it ? 1.640 2.000 ? 'X-RAY DIFFRACTION' ? c_scangle_it ? 2.370 2.500 ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 1.570 _refine_ls_shell.d_res_low 1.670 _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.percent_reflns_obs 91.700 _refine_ls_shell.number_reflns_R_work 20323 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.257 _refine_ls_shell.R_factor_R_free 0.280 _refine_ls_shell.percent_reflns_R_free 9.900 _refine_ls_shell.number_reflns_R_free 2238 _refine_ls_shell.R_factor_R_free_error 0.006 _refine_ls_shell.number_reflns_all 22561 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein.top 'X-RAY DIFFRACTION' 2 carbohydrate.param iso.top 'X-RAY DIFFRACTION' 3 water_rep.param fad.top 'X-RAY DIFFRACTION' 4 iso.par water.top 'X-RAY DIFFRACTION' 5 fad.par carbohydrate.top 'X-RAY DIFFRACTION' # _struct.entry_id 3GDP _struct.title 'Hydroxynitrile lyase from almond, monoclinic crystal form' _struct.pdbx_descriptor 'R-oxynitrile lyase isoenzyme 1 (E.C.4.1.2.10)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag N _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3GDP _struct_keywords.pdbx_keywords LYASE _struct_keywords.text 'HYDROXYNITRILE LYASE, FLAVIN, GMC OXIDOREDUCTASE, ALMOND, CYANOGENESIS, Flavoprotein, Lyase' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 4 ? F N N 4 ? G N N 4 ? H N N 5 ? I N N 6 ? J N N 6 ? K N N 4 ? L N N 4 ? M N N 7 ? N N N 4 ? O N N 2 ? P N N 3 ? Q N N 4 ? R N N 4 ? S N N 7 ? T N N 8 ? U N N 6 ? V N N 4 ? W N N 4 ? X N N 8 ? Y N N 6 ? Z N N 9 ? AA N N 4 ? BA N N 10 ? CA N N 10 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 PHE A 9 ? SER A 13 ? PHE A 9 SER A 13 5 ? 5 HELX_P HELX_P2 2 THR A 19 ? LEU A 21 ? THR A 19 LEU A 21 5 ? 3 HELX_P HELX_P3 3 SER A 37 ? SER A 46 ? SER A 37 SER A 46 1 ? 10 HELX_P HELX_P4 4 LEU A 59 ? ASP A 70 ? LEU A 59 ASP A 70 5 ? 12 HELX_P HELX_P5 5 GLY A 71 ? GLN A 78 ? GLY A 71 GLN A 78 1 ? 8 HELX_P HELX_P6 6 GLY A 104 ? ILE A 109 ? GLY A 104 ILE A 109 5 ? 6 HELX_P HELX_P7 7 ASP A 130 ? VAL A 146 ? ASP A 130 VAL A 146 1 ? 17 HELX_P HELX_P8 8 GLN A 152 ? ALA A 165 ? GLN A 152 ALA A 165 1 ? 14 HELX_P HELX_P9 9 ALA A 196 ? GLY A 204 ? ALA A 196 GLY A 204 5 ? 9 HELX_P HELX_P10 10 ALA A 257 ? SER A 269 ? ALA A 257 SER A 269 1 ? 13 HELX_P HELX_P11 11 PRO A 273 ? LEU A 280 ? PRO A 273 LEU A 280 1 ? 8 HELX_P HELX_P12 12 ASN A 392 ? SER A 411 ? ASN A 392 SER A 411 1 ? 20 HELX_P HELX_P13 13 THR A 412 ? LYS A 419 ? THR A 412 LYS A 419 5 ? 8 HELX_P HELX_P14 14 ASP A 442 ? VAL A 454 ? ASP A 442 VAL A 454 1 ? 13 HELX_P HELX_P15 15 ASP A 486 ? PHE A 490 ? ASP A 486 PHE A 490 5 ? 5 HELX_P HELX_P16 16 PRO A 498 ? SER A 520 ? PRO A 498 SER A 520 1 ? 23 HELX_P HELX_P17 17 PHE B 9 ? SER B 13 ? PHE B 9 SER B 13 5 ? 5 HELX_P HELX_P18 18 THR B 19 ? LEU B 21 ? THR B 19 LEU B 21 5 ? 3 HELX_P HELX_P19 19 SER B 37 ? SER B 46 ? SER B 37 SER B 46 1 ? 10 HELX_P HELX_P20 20 LEU B 59 ? ASP B 70 ? LEU B 59 ASP B 70 5 ? 12 HELX_P HELX_P21 21 GLY B 71 ? GLN B 78 ? GLY B 71 GLN B 78 1 ? 8 HELX_P HELX_P22 22 GLY B 104 ? ILE B 109 ? GLY B 104 ILE B 109 5 ? 6 HELX_P HELX_P23 23 ASP B 130 ? VAL B 146 ? ASP B 130 VAL B 146 1 ? 17 HELX_P HELX_P24 24 GLN B 152 ? ALA B 165 ? GLN B 152 ALA B 165 1 ? 14 HELX_P HELX_P25 25 ALA B 196 ? GLY B 204 ? ALA B 196 GLY B 204 5 ? 9 HELX_P HELX_P26 26 ALA B 257 ? SER B 269 ? ALA B 257 SER B 269 1 ? 13 HELX_P HELX_P27 27 PRO B 273 ? LEU B 280 ? PRO B 273 LEU B 280 1 ? 8 HELX_P HELX_P28 28 ASN B 392 ? SER B 411 ? ASN B 392 SER B 411 1 ? 20 HELX_P HELX_P29 29 THR B 412 ? LYS B 419 ? THR B 412 LYS B 419 5 ? 8 HELX_P HELX_P30 30 ASP B 442 ? VAL B 454 ? ASP B 442 VAL B 454 1 ? 13 HELX_P HELX_P31 31 PRO B 498 ? ASP B 521 ? PRO B 498 ASP B 521 1 ? 24 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 399 SG ? ? ? 1_555 A CYS 450 SG ? ? A CYS 399 A CYS 450 1_555 ? ? ? ? ? ? ? 2.038 ? disulf2 disulf ? ? B CYS 399 SG ? ? ? 1_555 B CYS 450 SG ? ? B CYS 399 B CYS 450 1_555 ? ? ? ? ? ? ? 2.029 ? covale1 covale ? ? A ASN 118 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 118 A NAG 524 1_555 ? ? ? ? ? ? ? 1.449 ? covale2 covale ? ? A ASN 135 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 135 A NAG 525 1_555 ? ? ? ? ? ? ? 1.450 ? covale3 covale ? ? A ASN 352 ND2 ? ? ? 1_555 N NAG . C1 ? ? A ASN 352 A NAG 533 1_555 ? ? ? ? ? ? ? 1.455 ? covale4 covale ? ? A ASN 392 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 392 A NAG 530 1_555 ? ? ? ? ? ? ? 1.450 ? covale5 covale ? ? B ASN 118 ND2 ? ? ? 1_555 AA NAG . C1 ? ? B ASN 118 B NAG 534 1_555 ? ? ? ? ? ? ? 1.450 ? covale6 covale ? ? B ASN 135 ND2 ? ? ? 1_555 V NAG . C1 ? ? B ASN 135 B NAG 529 1_555 ? ? ? ? ? ? ? 1.448 ? covale7 covale ? ? B ASN 392 ND2 ? ? ? 1_555 R NAG . C1 ? ? B ASN 392 B NAG 525 1_555 ? ? ? ? ? ? ? 1.446 ? covale8 covale ? ? F NAG . O3 ? ? ? 1_555 H FUL . C1 ? ? A NAG 525 A FUL 527 1_555 ? ? ? ? ? ? ? 1.399 ? covale9 covale ? ? F NAG . O4 ? ? ? 1_555 G NAG . C1 ? ? A NAG 525 A NAG 526 1_555 ? ? ? ? ? ? ? 1.393 ? covale10 covale ? ? G NAG . O4 ? ? ? 1_555 I MAN . C1 ? ? A NAG 526 A MAN 528 1_555 ? ? ? ? ? ? ? 1.390 ? covale11 covale ? ? I MAN . O6 ? ? ? 1_555 J MAN . C1 ? ? A MAN 528 A MAN 529 1_555 ? ? ? ? ? ? ? 1.396 ? covale12 covale ? ? K NAG . O3 ? ? ? 1_555 M FUC . C1 ? ? A NAG 530 A FUC 532 1_555 ? ? ? ? ? ? ? 1.403 ? covale13 covale ? ? K NAG . O4 ? ? ? 1_555 L NAG . C1 ? ? A NAG 530 A NAG 531 1_555 ? ? ? ? ? ? ? 1.390 ? covale14 covale ? ? Q NAG . C1 ? ? ? 1_555 R NAG . O4 ? ? B NAG 524 B NAG 525 1_555 ? ? ? ? ? ? ? 1.384 ? covale15 covale ? ? Q NAG . O4 ? ? ? 1_555 T BMA . C1 ? ? B NAG 524 B BMA 527 1_555 ? ? ? ? ? ? ? 1.385 ? covale16 covale ? ? R NAG . O3 ? ? ? 1_555 S FUC . C1 ? ? B NAG 525 B FUC 526 1_555 ? ? ? ? ? ? ? 1.401 ? covale17 covale ? ? T BMA . O3 ? ? ? 1_555 U MAN . C1 ? ? B BMA 527 B MAN 528 1_555 ? ? ? ? ? ? ? 1.399 ? covale18 covale ? ? V NAG . O4 ? ? ? 1_555 W NAG . C1 ? ? B NAG 529 B NAG 530 1_555 ? ? ? ? ? ? ? 1.389 ? covale19 covale ? ? W NAG . O4 ? ? ? 1_555 X BMA . C1 ? ? B NAG 530 B BMA 531 1_555 ? ? ? ? ? ? ? 1.389 ? covale20 covale ? ? X BMA . O6 ? ? ? 1_555 Y MAN . C1 ? ? B BMA 531 B MAN 532 1_555 ? ? ? ? ? ? ? 1.397 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 HIS 168 A . ? HIS 168 A PRO 169 A ? PRO 169 A 1 0.00 2 ALA 225 A . ? ALA 225 A PRO 226 A ? PRO 226 A 1 -2.26 3 GLY 364 A . ? GLY 364 A PRO 365 A ? PRO 365 A 1 -0.15 4 HIS 168 B . ? HIS 168 B PRO 169 B ? PRO 169 B 1 -0.64 5 ALA 225 B . ? ALA 225 B PRO 226 B ? PRO 226 B 1 -0.13 6 GLY 364 B . ? GLY 364 B PRO 365 B ? PRO 365 B 1 -0.43 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 7 ? B ? 6 ? C ? 2 ? D ? 2 ? E ? 7 ? F ? 7 ? G ? 2 ? H ? 4 ? I ? 7 ? J ? 6 ? K ? 2 ? L ? 2 ? M ? 7 ? N ? 7 ? O ? 2 ? P ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? parallel A 4 5 ? parallel A 5 6 ? anti-parallel A 6 7 ? anti-parallel B 1 2 ? parallel B 2 3 ? parallel B 3 4 ? parallel B 4 5 ? parallel B 5 6 ? parallel C 1 2 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel E 6 7 ? anti-parallel F 1 2 ? parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel F 5 6 ? anti-parallel F 6 7 ? anti-parallel G 1 2 ? parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel I 1 2 ? parallel I 2 3 ? parallel I 3 4 ? parallel I 4 5 ? parallel I 5 6 ? anti-parallel I 6 7 ? anti-parallel J 1 2 ? parallel J 2 3 ? parallel J 3 4 ? parallel J 4 5 ? parallel J 5 6 ? parallel K 1 2 ? anti-parallel L 1 2 ? anti-parallel M 1 2 ? parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? anti-parallel M 5 6 ? anti-parallel M 6 7 ? anti-parallel N 1 2 ? parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel N 4 5 ? anti-parallel N 5 6 ? anti-parallel N 6 7 ? anti-parallel O 1 2 ? parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ALA A 15 ? ASP A 17 ? ALA A 15 ASP A 17 A 2 LEU A 209 ? VAL A 213 ? LEU A 209 VAL A 213 A 3 VAL A 51 ? LEU A 54 ? VAL A 51 LEU A 54 A 4 GLU A 24 ? VAL A 32 ? GLU A 24 VAL A 32 A 5 PRO A 242 ? VAL A 255 ? PRO A 242 VAL A 255 A 6 LEU A 228 ? ARG A 236 ? LEU A 228 ARG A 236 A 7 SER A 216 ? ASN A 224 ? SER A 216 ASN A 224 B 1 ALA A 15 ? ASP A 17 ? ALA A 15 ASP A 17 B 2 LEU A 209 ? VAL A 213 ? LEU A 209 VAL A 213 B 3 VAL A 51 ? LEU A 54 ? VAL A 51 LEU A 54 B 4 GLU A 24 ? VAL A 32 ? GLU A 24 VAL A 32 B 5 PRO A 242 ? VAL A 255 ? PRO A 242 VAL A 255 B 6 LEU A 482 ? VAL A 484 ? LEU A 482 VAL A 484 C 1 VAL A 86 ? VAL A 90 ? VAL A 86 VAL A 90 C 2 ASP A 96 ? GLY A 100 ? ASP A 96 GLY A 100 D 1 VAL A 113 ? TYR A 114 ? VAL A 113 TYR A 114 D 2 GLY A 185 ? SER A 186 ? GLY A 185 SER A 186 E 1 ASN A 170 ? PHE A 173 ? ASN A 170 PHE A 173 E 2 GLY A 180 ? ILE A 183 ? GLY A 180 ILE A 183 E 3 VAL A 318 ? ILE A 321 ? VAL A 318 ILE A 321 E 4 PHE A 325 ? SER A 332 ? PHE A 325 SER A 332 E 5 PHE A 355 ? VAL A 362 ? PHE A 355 VAL A 362 E 6 PRO A 299 ? ILE A 305 ? PRO A 299 ILE A 305 E 7 ILE A 431 ? LEU A 432 ? ILE A 431 LEU A 432 F 1 ASN A 170 ? PHE A 173 ? ASN A 170 PHE A 173 F 2 GLY A 180 ? ILE A 183 ? GLY A 180 ILE A 183 F 3 VAL A 318 ? ILE A 321 ? VAL A 318 ILE A 321 F 4 PHE A 325 ? SER A 332 ? PHE A 325 SER A 332 F 5 PHE A 355 ? VAL A 362 ? PHE A 355 VAL A 362 F 6 PRO A 299 ? ILE A 305 ? PRO A 299 ILE A 305 F 7 ALA A 455 ? SER A 456 ? ALA A 455 SER A 456 G 1 VAL A 271 ? GLY A 272 ? VAL A 271 GLY A 272 G 2 LEU A 286 ? SER A 287 ? LEU A 286 SER A 287 H 1 ASN A 384 ? VAL A 385 ? ASN A 384 VAL A 385 H 2 GLY A 369 ? THR A 372 ? GLY A 369 THR A 372 H 3 GLN A 293 ? HIS A 296 ? GLN A 293 HIS A 296 H 4 HIS A 461 ? GLY A 462 ? HIS A 461 GLY A 462 I 1 ALA B 15 ? ASP B 17 ? ALA B 15 ASP B 17 I 2 LEU B 209 ? VAL B 213 ? LEU B 209 VAL B 213 I 3 VAL B 51 ? LEU B 54 ? VAL B 51 LEU B 54 I 4 GLU B 24 ? VAL B 32 ? GLU B 24 VAL B 32 I 5 PRO B 242 ? VAL B 255 ? PRO B 242 VAL B 255 I 6 ALA B 230 ? ARG B 236 ? ALA B 230 ARG B 236 I 7 SER B 216 ? PHE B 222 ? SER B 216 PHE B 222 J 1 ALA B 15 ? ASP B 17 ? ALA B 15 ASP B 17 J 2 LEU B 209 ? VAL B 213 ? LEU B 209 VAL B 213 J 3 VAL B 51 ? LEU B 54 ? VAL B 51 LEU B 54 J 4 GLU B 24 ? VAL B 32 ? GLU B 24 VAL B 32 J 5 PRO B 242 ? VAL B 255 ? PRO B 242 VAL B 255 J 6 LEU B 482 ? VAL B 484 ? LEU B 482 VAL B 484 K 1 VAL B 86 ? VAL B 90 ? VAL B 86 VAL B 90 K 2 ASP B 96 ? GLY B 100 ? ASP B 96 GLY B 100 L 1 VAL B 113 ? TYR B 114 ? VAL B 113 TYR B 114 L 2 GLY B 185 ? SER B 186 ? GLY B 185 SER B 186 M 1 ASN B 170 ? PHE B 173 ? ASN B 170 PHE B 173 M 2 GLY B 180 ? ILE B 183 ? GLY B 180 ILE B 183 M 3 VAL B 318 ? ILE B 321 ? VAL B 318 ILE B 321 M 4 PHE B 325 ? SER B 332 ? PHE B 325 SER B 332 M 5 PHE B 355 ? VAL B 362 ? PHE B 355 VAL B 362 M 6 PRO B 299 ? ILE B 305 ? PRO B 299 ILE B 305 M 7 ILE B 431 ? LEU B 432 ? ILE B 431 LEU B 432 N 1 ASN B 170 ? PHE B 173 ? ASN B 170 PHE B 173 N 2 GLY B 180 ? ILE B 183 ? GLY B 180 ILE B 183 N 3 VAL B 318 ? ILE B 321 ? VAL B 318 ILE B 321 N 4 PHE B 325 ? SER B 332 ? PHE B 325 SER B 332 N 5 PHE B 355 ? VAL B 362 ? PHE B 355 VAL B 362 N 6 PRO B 299 ? ILE B 305 ? PRO B 299 ILE B 305 N 7 ALA B 455 ? SER B 456 ? ALA B 455 SER B 456 O 1 VAL B 271 ? GLY B 272 ? VAL B 271 GLY B 272 O 2 LEU B 286 ? SER B 287 ? LEU B 286 SER B 287 P 1 ASN B 384 ? VAL B 385 ? ASN B 384 VAL B 385 P 2 GLY B 369 ? THR B 372 ? GLY B 369 THR B 372 P 3 GLN B 293 ? HIS B 296 ? GLN B 293 HIS B 296 P 4 HIS B 461 ? GLY B 462 ? HIS B 461 GLY B 462 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N TYR A 16 ? N TYR A 16 O VAL A 211 ? O VAL A 211 A 2 3 O GLY A 212 ? O GLY A 212 N VAL A 53 ? N VAL A 53 A 3 4 O LEU A 52 ? O LEU A 52 N ILE A 31 ? N ILE A 31 A 4 5 N TYR A 27 ? N TYR A 27 O PHE A 246 ? O PHE A 246 A 5 6 O HIS A 243 ? O HIS A 243 N TYR A 235 ? N TYR A 235 A 6 7 O GLY A 232 ? O GLY A 232 N ILE A 221 ? N ILE A 221 B 1 2 N TYR A 16 ? N TYR A 16 O VAL A 211 ? O VAL A 211 B 2 3 O GLY A 212 ? O GLY A 212 N VAL A 53 ? N VAL A 53 B 3 4 O LEU A 52 ? O LEU A 52 N ILE A 31 ? N ILE A 31 B 4 5 N TYR A 27 ? N TYR A 27 O PHE A 246 ? O PHE A 246 B 5 6 N VAL A 255 ? N VAL A 255 O ARG A 483 ? O ARG A 483 C 1 2 N GLU A 87 ? N GLU A 87 O ARG A 99 ? O ARG A 99 D 1 2 N TYR A 114 ? N TYR A 114 O GLY A 185 ? O GLY A 185 E 1 2 N HIS A 171 ? N HIS A 171 O THR A 181 ? O THR A 181 E 2 3 N GLY A 180 ? N GLY A 180 O ILE A 321 ? O ILE A 321 E 3 4 N GLY A 320 ? N GLY A 320 O GLN A 327 ? O GLN A 327 E 4 5 N TYR A 326 ? N TYR A 326 O LYS A 361 ? O LYS A 361 E 5 6 O PHE A 358 ? O PHE A 358 N ILE A 303 ? N ILE A 303 E 6 7 N ASN A 304 ? N ASN A 304 O LEU A 432 ? O LEU A 432 F 1 2 N HIS A 171 ? N HIS A 171 O THR A 181 ? O THR A 181 F 2 3 N GLY A 180 ? N GLY A 180 O ILE A 321 ? O ILE A 321 F 3 4 N GLY A 320 ? N GLY A 320 O GLN A 327 ? O GLN A 327 F 4 5 N TYR A 326 ? N TYR A 326 O LYS A 361 ? O LYS A 361 F 5 6 O PHE A 358 ? O PHE A 358 N ILE A 303 ? N ILE A 303 F 6 7 N ARG A 300 ? N ARG A 300 O ALA A 455 ? O ALA A 455 G 1 2 N GLY A 272 ? N GLY A 272 O LEU A 286 ? O LEU A 286 H 1 2 O ASN A 384 ? O ASN A 384 N THR A 372 ? N THR A 372 H 2 3 O GLY A 369 ? O GLY A 369 N LEU A 295 ? N LEU A 295 H 3 4 N HIS A 296 ? N HIS A 296 O HIS A 461 ? O HIS A 461 I 1 2 N TYR B 16 ? N TYR B 16 O VAL B 211 ? O VAL B 211 I 2 3 O GLY B 212 ? O GLY B 212 N VAL B 53 ? N VAL B 53 I 3 4 O LEU B 52 ? O LEU B 52 N ILE B 31 ? N ILE B 31 I 4 5 N GLY B 25 ? N GLY B 25 O PHE B 246 ? O PHE B 246 I 5 6 O HIS B 243 ? O HIS B 243 N TYR B 235 ? N TYR B 235 I 6 7 O GLY B 232 ? O GLY B 232 N ILE B 221 ? N ILE B 221 J 1 2 N TYR B 16 ? N TYR B 16 O VAL B 211 ? O VAL B 211 J 2 3 O GLY B 212 ? O GLY B 212 N VAL B 53 ? N VAL B 53 J 3 4 O LEU B 52 ? O LEU B 52 N ILE B 31 ? N ILE B 31 J 4 5 N GLY B 25 ? N GLY B 25 O PHE B 246 ? O PHE B 246 J 5 6 N VAL B 255 ? N VAL B 255 O ARG B 483 ? O ARG B 483 K 1 2 N GLU B 87 ? N GLU B 87 O ARG B 99 ? O ARG B 99 L 1 2 N TYR B 114 ? N TYR B 114 O GLY B 185 ? O GLY B 185 M 1 2 N HIS B 171 ? N HIS B 171 O THR B 181 ? O THR B 181 M 2 3 N GLY B 180 ? N GLY B 180 O ILE B 321 ? O ILE B 321 M 3 4 N GLY B 320 ? N GLY B 320 O GLN B 327 ? O GLN B 327 M 4 5 N TYR B 326 ? N TYR B 326 O LYS B 361 ? O LYS B 361 M 5 6 O PHE B 358 ? O PHE B 358 N ILE B 303 ? N ILE B 303 M 6 7 N ASN B 304 ? N ASN B 304 O LEU B 432 ? O LEU B 432 N 1 2 N HIS B 171 ? N HIS B 171 O THR B 181 ? O THR B 181 N 2 3 N GLY B 180 ? N GLY B 180 O ILE B 321 ? O ILE B 321 N 3 4 N GLY B 320 ? N GLY B 320 O GLN B 327 ? O GLN B 327 N 4 5 N TYR B 326 ? N TYR B 326 O LYS B 361 ? O LYS B 361 N 5 6 O PHE B 358 ? O PHE B 358 N ILE B 303 ? N ILE B 303 N 6 7 N ARG B 300 ? N ARG B 300 O ALA B 455 ? O ALA B 455 O 1 2 N GLY B 272 ? N GLY B 272 O LEU B 286 ? O LEU B 286 P 1 2 O ASN B 384 ? O ASN B 384 N THR B 372 ? N THR B 372 P 2 3 O GLY B 369 ? O GLY B 369 N LEU B 295 ? N LEU B 295 P 3 4 N HIS B 296 ? N HIS B 296 O HIS B 461 ? O HIS B 461 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE IPA A 522' AC2 Software ? ? ? ? 39 'BINDING SITE FOR RESIDUE FAD A 523' AC3 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 524' AC4 Software ? ? ? ? 12 'BINDING SITE FOR RESIDUE NAG A 525' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 526' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUL A 527' AC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 528' AC8 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MAN A 529' AC9 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG A 530' BC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 531' BC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUC A 532' BC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 533' BC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE IPA B 522' BC5 Software ? ? ? ? 39 'BINDING SITE FOR RESIDUE FAD B 523' BC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 524' BC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 525' BC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUC B 526' BC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE BMA B 527' CC1 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE MAN B 528' CC2 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG B 529' CC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 530' CC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE BMA B 531' CC5 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE MAN B 532' CC6 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NDG B 533' CC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 534' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 7 ILE A 121 ? ILE A 121 . ? 1_555 ? 2 AC1 7 SER A 125 ? SER A 125 . ? 1_555 ? 3 AC1 7 PHE A 490 ? PHE A 490 . ? 1_555 ? 4 AC1 7 TYR A 492 ? TYR A 492 . ? 1_555 ? 5 AC1 7 HOH BA . ? HOH A 866 . ? 1_555 ? 6 AC1 7 HOH BA . ? HOH A 1156 . ? 1_555 ? 7 AC1 7 HOH BA . ? HOH A 1176 . ? 1_555 ? 8 AC2 39 GLY A 33 ? GLY A 33 . ? 1_555 ? 9 AC2 39 GLY A 35 ? GLY A 35 . ? 1_555 ? 10 AC2 39 THR A 36 ? THR A 36 . ? 1_555 ? 11 AC2 39 SER A 37 ? SER A 37 . ? 1_555 ? 12 AC2 39 LEU A 54 ? LEU A 54 . ? 1_555 ? 13 AC2 39 GLU A 55 ? GLU A 55 . ? 1_555 ? 14 AC2 39 ARG A 56 ? ARG A 56 . ? 1_555 ? 15 AC2 39 VAL A 98 ? VAL A 98 . ? 1_555 ? 16 AC2 39 GLY A 100 ? GLY A 100 . ? 1_555 ? 17 AC2 39 ARG A 101 ? ARG A 101 . ? 1_555 ? 18 AC2 39 VAL A 102 ? VAL A 102 . ? 1_555 ? 19 AC2 39 GLY A 105 ? GLY A 105 . ? 1_555 ? 20 AC2 39 THR A 106 ? THR A 106 . ? 1_555 ? 21 AC2 39 ASN A 110 ? ASN A 110 . ? 1_555 ? 22 AC2 39 ALA A 111 ? ALA A 111 . ? 1_555 ? 23 AC2 39 GLY A 112 ? GLY A 112 . ? 1_555 ? 24 AC2 39 VAL A 113 ? VAL A 113 . ? 1_555 ? 25 AC2 39 ALA A 215 ? ALA A 215 . ? 1_555 ? 26 AC2 39 VAL A 217 ? VAL A 217 . ? 1_555 ? 27 AC2 39 SER A 256 ? SER A 256 . ? 1_555 ? 28 AC2 39 ALA A 257 ? ALA A 257 . ? 1_555 ? 29 AC2 39 VAL A 379 ? VAL A 379 . ? 1_555 ? 30 AC2 39 TRP A 458 ? TRP A 458 . ? 1_555 ? 31 AC2 39 HIS A 459 ? HIS A 459 . ? 1_555 ? 32 AC2 39 ASP A 486 ? ASP A 486 . ? 1_555 ? 33 AC2 39 GLY A 487 ? GLY A 487 . ? 1_555 ? 34 AC2 39 HIS A 497 ? HIS A 497 . ? 1_555 ? 35 AC2 39 PRO A 498 ? PRO A 498 . ? 1_555 ? 36 AC2 39 GLN A 499 ? GLN A 499 . ? 1_555 ? 37 AC2 39 TYR A 502 ? TYR A 502 . ? 1_555 ? 38 AC2 39 HOH BA . ? HOH A 593 . ? 1_555 ? 39 AC2 39 HOH BA . ? HOH A 694 . ? 1_555 ? 40 AC2 39 HOH BA . ? HOH A 777 . ? 1_555 ? 41 AC2 39 HOH BA . ? HOH A 831 . ? 1_555 ? 42 AC2 39 HOH BA . ? HOH A 835 . ? 1_555 ? 43 AC2 39 HOH BA . ? HOH A 845 . ? 1_555 ? 44 AC2 39 HOH BA . ? HOH A 853 . ? 1_555 ? 45 AC2 39 HOH BA . ? HOH A 879 . ? 1_555 ? 46 AC2 39 HOH BA . ? HOH A 920 . ? 1_555 ? 47 AC3 10 ASN A 118 ? ASN A 118 . ? 1_555 ? 48 AC3 10 HIS A 177 ? HIS A 177 . ? 1_555 ? 49 AC3 10 GLU A 179 ? GLU A 179 . ? 1_555 ? 50 AC3 10 ASN A 323 ? ASN A 323 . ? 1_555 ? 51 AC3 10 HOH BA . ? HOH A 632 . ? 1_555 ? 52 AC3 10 HOH BA . ? HOH A 827 . ? 1_555 ? 53 AC3 10 HOH BA . ? HOH A 925 . ? 1_555 ? 54 AC3 10 HOH BA . ? HOH A 1202 . ? 1_555 ? 55 AC3 10 HOH BA . ? HOH A 1299 . ? 1_555 ? 56 AC3 10 HOH BA . ? HOH A 1349 . ? 1_555 ? 57 AC4 12 ARG A 116 ? ARG A 116 . ? 1_555 ? 58 AC4 12 ASP A 132 ? ASP A 132 . ? 1_555 ? 59 AC4 12 ASN A 135 ? ASN A 135 . ? 1_555 ? 60 AC4 12 ASP A 176 ? ASP A 176 . ? 1_555 ? 61 AC4 12 NAG G . ? NAG A 526 . ? 1_555 ? 62 AC4 12 FUL H . ? FUL A 527 . ? 1_555 ? 63 AC4 12 HOH BA . ? HOH A 568 . ? 1_555 ? 64 AC4 12 HOH BA . ? HOH A 877 . ? 1_555 ? 65 AC4 12 HOH BA . ? HOH A 1088 . ? 1_555 ? 66 AC4 12 HOH BA . ? HOH A 1208 . ? 1_555 ? 67 AC4 12 HOH BA . ? HOH A 1213 . ? 1_555 ? 68 AC4 12 HOH BA . ? HOH A 1250 . ? 1_555 ? 69 AC5 6 THR A 119 ? THR A 119 . ? 1_555 ? 70 AC5 6 ASP A 176 ? ASP A 176 . ? 1_555 ? 71 AC5 6 NAG F . ? NAG A 525 . ? 1_555 ? 72 AC5 6 FUL H . ? FUL A 527 . ? 1_555 ? 73 AC5 6 MAN I . ? MAN A 528 . ? 1_555 ? 74 AC5 6 HOH BA . ? HOH A 538 . ? 1_555 ? 75 AC6 3 NAG F . ? NAG A 525 . ? 1_555 ? 76 AC6 3 NAG G . ? NAG A 526 . ? 1_555 ? 77 AC6 3 HOH BA . ? HOH A 568 . ? 1_555 ? 78 AC7 3 NAG G . ? NAG A 526 . ? 1_555 ? 79 AC7 3 MAN J . ? MAN A 529 . ? 1_555 ? 80 AC7 3 HOH BA . ? HOH A 554 . ? 1_555 ? 81 AC8 4 HIS A 171 ? HIS A 171 . ? 1_555 ? 82 AC8 4 GLU A 178 ? GLU A 178 . ? 1_555 ? 83 AC8 4 MAN I . ? MAN A 528 . ? 1_555 ? 84 AC8 4 HOH BA . ? HOH A 588 . ? 1_555 ? 85 AC9 7 LEU A 366 ? LEU A 366 . ? 1_555 ? 86 AC9 7 ASN A 392 ? ASN A 392 . ? 1_555 ? 87 AC9 7 NAG L . ? NAG A 531 . ? 1_555 ? 88 AC9 7 FUC M . ? FUC A 532 . ? 1_555 ? 89 AC9 7 HOH BA . ? HOH A 587 . ? 1_555 ? 90 AC9 7 HOH BA . ? HOH A 683 . ? 1_555 ? 91 AC9 7 HOH BA . ? HOH A 784 . ? 1_555 ? 92 BC1 3 NAG K . ? NAG A 530 . ? 1_555 ? 93 BC1 3 FUC M . ? FUC A 532 . ? 1_555 ? 94 BC1 3 HOH BA . ? HOH A 686 . ? 1_555 ? 95 BC2 3 NAG K . ? NAG A 530 . ? 1_555 ? 96 BC2 3 NAG L . ? NAG A 531 . ? 1_555 ? 97 BC2 3 HOH BA . ? HOH A 683 . ? 1_555 ? 98 BC3 6 ASN A 352 ? ASN A 352 . ? 1_555 ? 99 BC3 6 ASN A 430 ? ASN A 430 . ? 1_555 ? 100 BC3 6 HOH BA . ? HOH A 570 . ? 1_555 ? 101 BC3 6 HOH BA . ? HOH A 650 . ? 1_555 ? 102 BC3 6 HOH BA . ? HOH A 824 . ? 1_555 ? 103 BC3 6 HOH BA . ? HOH A 1301 . ? 1_555 ? 104 BC4 6 ILE B 121 ? ILE B 121 . ? 1_555 ? 105 BC4 6 PHE B 490 ? PHE B 490 . ? 1_555 ? 106 BC4 6 TYR B 492 ? TYR B 492 . ? 1_555 ? 107 BC4 6 HOH CA . ? HOH B 850 . ? 1_555 ? 108 BC4 6 HOH CA . ? HOH B 1002 . ? 1_555 ? 109 BC4 6 HOH CA . ? HOH B 1381 . ? 1_555 ? 110 BC5 39 GLY B 33 ? GLY B 33 . ? 1_555 ? 111 BC5 39 GLY B 35 ? GLY B 35 . ? 1_555 ? 112 BC5 39 THR B 36 ? THR B 36 . ? 1_555 ? 113 BC5 39 SER B 37 ? SER B 37 . ? 1_555 ? 114 BC5 39 LEU B 54 ? LEU B 54 . ? 1_555 ? 115 BC5 39 GLU B 55 ? GLU B 55 . ? 1_555 ? 116 BC5 39 ARG B 56 ? ARG B 56 . ? 1_555 ? 117 BC5 39 VAL B 98 ? VAL B 98 . ? 1_555 ? 118 BC5 39 GLY B 100 ? GLY B 100 . ? 1_555 ? 119 BC5 39 ARG B 101 ? ARG B 101 . ? 1_555 ? 120 BC5 39 VAL B 102 ? VAL B 102 . ? 1_555 ? 121 BC5 39 GLY B 105 ? GLY B 105 . ? 1_555 ? 122 BC5 39 THR B 106 ? THR B 106 . ? 1_555 ? 123 BC5 39 ASN B 110 ? ASN B 110 . ? 1_555 ? 124 BC5 39 ALA B 111 ? ALA B 111 . ? 1_555 ? 125 BC5 39 GLY B 112 ? GLY B 112 . ? 1_555 ? 126 BC5 39 VAL B 113 ? VAL B 113 . ? 1_555 ? 127 BC5 39 ALA B 215 ? ALA B 215 . ? 1_555 ? 128 BC5 39 VAL B 217 ? VAL B 217 . ? 1_555 ? 129 BC5 39 SER B 256 ? SER B 256 . ? 1_555 ? 130 BC5 39 ALA B 257 ? ALA B 257 . ? 1_555 ? 131 BC5 39 VAL B 379 ? VAL B 379 . ? 1_555 ? 132 BC5 39 TRP B 458 ? TRP B 458 . ? 1_555 ? 133 BC5 39 HIS B 459 ? HIS B 459 . ? 1_555 ? 134 BC5 39 ASP B 486 ? ASP B 486 . ? 1_555 ? 135 BC5 39 GLY B 487 ? GLY B 487 . ? 1_555 ? 136 BC5 39 HIS B 497 ? HIS B 497 . ? 1_555 ? 137 BC5 39 PRO B 498 ? PRO B 498 . ? 1_555 ? 138 BC5 39 GLN B 499 ? GLN B 499 . ? 1_555 ? 139 BC5 39 TYR B 502 ? TYR B 502 . ? 1_555 ? 140 BC5 39 HOH CA . ? HOH B 831 . ? 1_555 ? 141 BC5 39 HOH CA . ? HOH B 841 . ? 1_555 ? 142 BC5 39 HOH CA . ? HOH B 847 . ? 1_555 ? 143 BC5 39 HOH CA . ? HOH B 848 . ? 1_555 ? 144 BC5 39 HOH CA . ? HOH B 851 . ? 1_555 ? 145 BC5 39 HOH CA . ? HOH B 861 . ? 1_555 ? 146 BC5 39 HOH CA . ? HOH B 885 . ? 1_555 ? 147 BC5 39 HOH CA . ? HOH B 976 . ? 1_555 ? 148 BC5 39 HOH CA . ? HOH B 1058 . ? 1_555 ? 149 BC6 4 NAG R . ? NAG B 525 . ? 1_555 ? 150 BC6 4 FUC S . ? FUC B 526 . ? 1_555 ? 151 BC6 4 BMA T . ? BMA B 527 . ? 1_555 ? 152 BC6 4 HOH CA . ? HOH B 1432 . ? 1_555 ? 153 BC7 6 LEU B 366 ? LEU B 366 . ? 1_555 ? 154 BC7 6 ASN B 392 ? ASN B 392 . ? 1_555 ? 155 BC7 6 NAG Q . ? NAG B 524 . ? 1_555 ? 156 BC7 6 FUC S . ? FUC B 526 . ? 1_555 ? 157 BC7 6 HOH CA . ? HOH B 1007 . ? 1_555 ? 158 BC7 6 HOH CA . ? HOH B 1245 . ? 1_555 ? 159 BC8 3 NAG Q . ? NAG B 524 . ? 1_555 ? 160 BC8 3 NAG R . ? NAG B 525 . ? 1_555 ? 161 BC8 3 HOH CA . ? HOH B 1277 . ? 1_555 ? 162 BC9 3 ASP A 422 ? ASP A 422 . ? 1_555 ? 163 BC9 3 NAG Q . ? NAG B 524 . ? 1_555 ? 164 BC9 3 MAN U . ? MAN B 528 . ? 1_555 ? 165 CC1 9 LYS A 416 ? LYS A 416 . ? 1_555 ? 166 CC1 9 PRO A 417 ? PRO A 417 . ? 1_555 ? 167 CC1 9 LYS A 419 ? LYS A 419 . ? 1_555 ? 168 CC1 9 ASP A 422 ? ASP A 422 . ? 1_555 ? 169 CC1 9 HOH BA . ? HOH A 607 . ? 1_555 ? 170 CC1 9 BMA T . ? BMA B 527 . ? 1_555 ? 171 CC1 9 HOH CA . ? HOH B 535 . ? 1_555 ? 172 CC1 9 HOH CA . ? HOH B 590 . ? 1_555 ? 173 CC1 9 HOH CA . ? HOH B 625 . ? 1_555 ? 174 CC2 10 ARG B 116 ? ARG B 116 . ? 1_555 ? 175 CC2 10 ASP B 132 ? ASP B 132 . ? 1_555 ? 176 CC2 10 ASN B 135 ? ASN B 135 . ? 1_555 ? 177 CC2 10 ASP B 176 ? ASP B 176 . ? 1_555 ? 178 CC2 10 NAG W . ? NAG B 530 . ? 1_555 ? 179 CC2 10 HOH CA . ? HOH B 866 . ? 1_555 ? 180 CC2 10 HOH CA . ? HOH B 880 . ? 1_555 ? 181 CC2 10 HOH CA . ? HOH B 1276 . ? 1_555 ? 182 CC2 10 HOH CA . ? HOH B 1283 . ? 1_555 ? 183 CC2 10 HOH CA . ? HOH B 1323 . ? 1_555 ? 184 CC3 5 GLU B 178 ? GLU B 178 . ? 1_555 ? 185 CC3 5 NAG V . ? NAG B 529 . ? 1_555 ? 186 CC3 5 BMA X . ? BMA B 531 . ? 1_555 ? 187 CC3 5 HOH CA . ? HOH B 1341 . ? 1_555 ? 188 CC3 5 HOH CA . ? HOH B 1373 . ? 1_555 ? 189 CC4 4 NAG W . ? NAG B 530 . ? 1_555 ? 190 CC4 4 MAN Y . ? MAN B 532 . ? 1_555 ? 191 CC4 4 HOH CA . ? HOH B 1291 . ? 1_555 ? 192 CC4 4 HOH CA . ? HOH B 1380 . ? 1_555 ? 193 CC5 5 HIS B 171 ? HIS B 171 . ? 1_555 ? 194 CC5 5 GLU B 178 ? GLU B 178 . ? 1_555 ? 195 CC5 5 BMA X . ? BMA B 531 . ? 1_555 ? 196 CC5 5 HOH CA . ? HOH B 1097 . ? 1_555 ? 197 CC5 5 HOH CA . ? HOH B 1370 . ? 1_555 ? 198 CC6 7 ALA A 519 ? ALA A 519 . ? 1_465 ? 199 CC6 7 HOH BA . ? HOH A 1267 . ? 1_465 ? 200 CC6 7 ASN B 352 ? ASN B 352 . ? 1_555 ? 201 CC6 7 ASN B 430 ? ASN B 430 . ? 1_555 ? 202 CC6 7 HOH CA . ? HOH B 1232 . ? 1_555 ? 203 CC6 7 HOH CA . ? HOH B 1502 . ? 1_555 ? 204 CC6 7 HOH CA . ? HOH B 1597 . ? 1_555 ? 205 CC7 6 ASN B 118 ? ASN B 118 . ? 1_555 ? 206 CC7 6 SER B 120 ? SER B 120 . ? 1_555 ? 207 CC7 6 HIS B 177 ? HIS B 177 . ? 1_555 ? 208 CC7 6 ASN B 323 ? ASN B 323 . ? 1_555 ? 209 CC7 6 HOH CA . ? HOH B 911 . ? 1_555 ? 210 CC7 6 HOH CA . ? HOH B 921 . ? 1_555 ? # _database_PDB_matrix.entry_id 3GDP _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.000000 _database_PDB_matrix.origx_vector[2] 0.000000 _database_PDB_matrix.origx_vector[3] 0.000000 # _atom_sites.entry_id 3GDP _atom_sites.fract_transf_matrix[1][1] 0.014482 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.004260 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010671 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.011945 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LEU A 1 1 ? 73.998 -4.750 -10.138 1.00 17.36 ? 1 LEU A N 1 ATOM 2 C CA . LEU A 1 1 ? 73.520 -3.492 -10.785 1.00 16.58 ? 1 LEU A CA 1 ATOM 3 C C . LEU A 1 1 ? 74.540 -2.367 -10.644 1.00 15.74 ? 1 LEU A C 1 ATOM 4 O O . LEU A 1 1 ? 75.341 -2.349 -9.706 1.00 16.78 ? 1 LEU A O 1 ATOM 5 C CB . LEU A 1 1 ? 72.184 -3.062 -10.175 1.00 19.17 ? 1 LEU A CB 1 ATOM 6 C CG . LEU A 1 1 ? 71.026 -4.046 -10.356 1.00 19.58 ? 1 LEU A CG 1 ATOM 7 C CD1 . LEU A 1 1 ? 69.804 -3.548 -9.607 1.00 22.23 ? 1 LEU A CD1 1 ATOM 8 C CD2 . LEU A 1 1 ? 70.724 -4.204 -11.836 1.00 21.15 ? 1 LEU A CD2 1 ATOM 9 N N . ALA A 1 2 ? 74.498 -1.424 -11.580 1.00 13.93 ? 2 ALA A N 1 ATOM 10 C CA . ALA A 1 2 ? 75.421 -0.297 -11.583 1.00 14.09 ? 2 ALA A CA 1 ATOM 11 C C . ALA A 1 2 ? 74.831 0.939 -10.919 1.00 14.65 ? 2 ALA A C 1 ATOM 12 O O . ALA A 1 2 ? 73.645 0.980 -10.591 1.00 14.86 ? 2 ALA A O 1 ATOM 13 C CB . ALA A 1 2 ? 75.825 0.033 -13.016 1.00 13.90 ? 2 ALA A CB 1 ATOM 14 N N . THR A 1 3 ? 75.678 1.943 -10.723 1.00 14.42 ? 3 THR A N 1 ATOM 15 C CA . THR A 1 3 ? 75.263 3.198 -10.115 1.00 16.71 ? 3 THR A CA 1 ATOM 16 C C . THR A 1 3 ? 75.373 4.306 -11.155 1.00 15.46 ? 3 THR A C 1 ATOM 17 O O . THR A 1 3 ? 76.358 4.387 -11.887 1.00 14.88 ? 3 THR A O 1 ATOM 18 C CB . THR A 1 3 ? 76.151 3.548 -8.906 1.00 18.55 ? 3 THR A CB 1 ATOM 19 O OG1 . THR A 1 3 ? 76.065 2.499 -7.934 1.00 21.26 ? 3 THR A OG1 1 ATOM 20 C CG2 . THR A 1 3 ? 75.700 4.857 -8.271 1.00 21.08 ? 3 THR A CG2 1 ATOM 21 N N . THR A 1 4 ? 74.349 5.150 -11.221 1.00 15.71 ? 4 THR A N 1 ATOM 22 C CA . THR A 1 4 ? 74.307 6.258 -12.172 1.00 16.15 ? 4 THR A CA 1 ATOM 23 C C . THR A 1 4 ? 75.652 6.970 -12.319 1.00 16.62 ? 4 THR A C 1 ATOM 24 O O . THR A 1 4 ? 76.296 7.316 -11.328 1.00 16.21 ? 4 THR A O 1 ATOM 25 C CB . THR A 1 4 ? 73.227 7.277 -11.750 1.00 17.41 ? 4 THR A CB 1 ATOM 26 O OG1 . THR A 1 4 ? 71.935 6.660 -11.841 1.00 18.68 ? 4 THR A OG1 1 ATOM 27 C CG2 . THR A 1 4 ? 73.268 8.512 -12.637 1.00 16.01 ? 4 THR A CG2 1 ATOM 28 N N . SER A 1 5 ? 76.068 7.180 -13.565 1.00 16.27 ? 5 SER A N 1 ATOM 29 C CA . SER A 1 5 ? 77.334 7.848 -13.862 1.00 16.95 ? 5 SER A CA 1 ATOM 30 C C . SER A 1 5 ? 77.373 8.234 -15.337 1.00 16.27 ? 5 SER A C 1 ATOM 31 O O . SER A 1 5 ? 76.519 7.807 -16.117 1.00 15.04 ? 5 SER A O 1 ATOM 32 C CB . SER A 1 5 ? 78.508 6.916 -13.564 1.00 17.87 ? 5 SER A CB 1 ATOM 33 O OG . SER A 1 5 ? 78.596 5.891 -14.542 1.00 20.28 ? 5 SER A OG 1 ATOM 34 N N . ASP A 1 6 ? 78.362 9.037 -15.720 1.00 15.62 ? 6 ASP A N 1 ATOM 35 C CA . ASP A 1 6 ? 78.495 9.442 -17.114 1.00 15.37 ? 6 ASP A CA 1 ATOM 36 C C . ASP A 1 6 ? 78.836 8.220 -17.958 1.00 13.85 ? 6 ASP A C 1 ATOM 37 O O . ASP A 1 6 ? 79.359 7.229 -17.446 1.00 12.70 ? 6 ASP A O 1 ATOM 38 C CB . ASP A 1 6 ? 79.617 10.471 -17.296 1.00 17.74 ? 6 ASP A CB 1 ATOM 39 C CG . ASP A 1 6 ? 79.406 11.728 -16.479 1.00 21.28 ? 6 ASP A CG 1 ATOM 40 O OD1 . ASP A 1 6 ? 78.242 12.135 -16.286 1.00 22.09 ? 6 ASP A OD1 1 ATOM 41 O OD2 . ASP A 1 6 ? 80.419 12.319 -16.049 1.00 21.90 ? 6 ASP A OD2 1 ATOM 42 N N . HIS A 1 7 ? 78.534 8.293 -19.249 1.00 13.01 ? 7 HIS A N 1 ATOM 43 C CA . HIS A 1 7 ? 78.851 7.197 -20.159 1.00 13.79 ? 7 HIS A CA 1 ATOM 44 C C . HIS A 1 7 ? 80.379 7.100 -20.134 1.00 13.77 ? 7 HIS A C 1 ATOM 45 O O . HIS A 1 7 ? 81.069 8.095 -20.360 1.00 14.37 ? 7 HIS A O 1 ATOM 46 C CB . HIS A 1 7 ? 78.366 7.528 -21.571 1.00 12.00 ? 7 HIS A CB 1 ATOM 47 C CG . HIS A 1 7 ? 78.432 6.372 -22.521 1.00 12.13 ? 7 HIS A CG 1 ATOM 48 N ND1 . HIS A 1 7 ? 77.368 5.525 -22.736 1.00 10.61 ? 7 HIS A ND1 1 ATOM 49 C CD2 . HIS A 1 7 ? 79.440 5.920 -23.304 1.00 11.47 ? 7 HIS A CD2 1 ATOM 50 C CE1 . HIS A 1 7 ? 77.717 4.599 -23.614 1.00 8.79 ? 7 HIS A CE1 1 ATOM 51 N NE2 . HIS A 1 7 ? 78.968 4.817 -23.973 1.00 9.87 ? 7 HIS A NE2 1 ATOM 52 N N . ASP A 1 8 ? 80.902 5.910 -19.859 1.00 13.45 ? 8 ASP A N 1 ATOM 53 C CA . ASP A 1 8 ? 82.349 5.704 -19.763 1.00 13.99 ? 8 ASP A CA 1 ATOM 54 C C . ASP A 1 8 ? 83.063 5.514 -21.104 1.00 14.58 ? 8 ASP A C 1 ATOM 55 O O . ASP A 1 8 ? 82.995 4.442 -21.703 1.00 13.33 ? 8 ASP A O 1 ATOM 56 C CB . ASP A 1 8 ? 82.626 4.499 -18.862 1.00 15.32 ? 8 ASP A CB 1 ATOM 57 C CG . ASP A 1 8 ? 84.092 4.357 -18.505 1.00 14.55 ? 8 ASP A CG 1 ATOM 58 O OD1 . ASP A 1 8 ? 84.930 5.063 -19.104 1.00 15.74 ? 8 ASP A OD1 1 ATOM 59 O OD2 . ASP A 1 8 ? 84.400 3.526 -17.626 1.00 16.79 ? 8 ASP A OD2 1 ATOM 60 N N . PHE A 1 9 ? 83.758 6.554 -21.561 1.00 12.66 ? 9 PHE A N 1 ATOM 61 C CA . PHE A 1 9 ? 84.490 6.501 -22.824 1.00 12.93 ? 9 PHE A CA 1 ATOM 62 C C . PHE A 1 9 ? 85.995 6.309 -22.636 1.00 12.55 ? 9 PHE A C 1 ATOM 63 O O . PHE A 1 9 ? 86.790 6.756 -23.465 1.00 12.57 ? 9 PHE A O 1 ATOM 64 C CB . PHE A 1 9 ? 84.256 7.778 -23.641 1.00 14.05 ? 9 PHE A CB 1 ATOM 65 C CG . PHE A 1 9 ? 82.901 7.854 -24.292 1.00 14.68 ? 9 PHE A CG 1 ATOM 66 C CD1 . PHE A 1 9 ? 81.959 8.787 -23.867 1.00 13.07 ? 9 PHE A CD1 1 ATOM 67 C CD2 . PHE A 1 9 ? 82.579 7.012 -25.353 1.00 13.05 ? 9 PHE A CD2 1 ATOM 68 C CE1 . PHE A 1 9 ? 80.716 8.883 -24.491 1.00 14.42 ? 9 PHE A CE1 1 ATOM 69 C CE2 . PHE A 1 9 ? 81.341 7.098 -25.984 1.00 13.51 ? 9 PHE A CE2 1 ATOM 70 C CZ . PHE A 1 9 ? 80.406 8.039 -25.553 1.00 14.08 ? 9 PHE A CZ 1 ATOM 71 N N . SER A 1 10 ? 86.391 5.645 -21.555 1.00 13.59 ? 10 SER A N 1 ATOM 72 C CA . SER A 1 10 ? 87.810 5.415 -21.298 1.00 14.00 ? 10 SER A CA 1 ATOM 73 C C . SER A 1 10 ? 88.459 4.608 -22.420 1.00 14.12 ? 10 SER A C 1 ATOM 74 O O . SER A 1 10 ? 89.637 4.790 -22.729 1.00 13.98 ? 10 SER A O 1 ATOM 75 C CB . SER A 1 10 ? 87.998 4.680 -19.968 1.00 14.72 ? 10 SER A CB 1 ATOM 76 O OG . SER A 1 10 ? 87.539 5.463 -18.880 1.00 16.00 ? 10 SER A OG 1 ATOM 77 N N . TYR A 1 11 ? 87.677 3.723 -23.033 1.00 12.15 ? 11 TYR A N 1 ATOM 78 C CA . TYR A 1 11 ? 88.165 2.873 -24.112 1.00 12.75 ? 11 TYR A CA 1 ATOM 79 C C . TYR A 1 11 ? 88.630 3.641 -25.347 1.00 12.06 ? 11 TYR A C 1 ATOM 80 O O . TYR A 1 11 ? 89.262 3.071 -26.234 1.00 12.33 ? 11 TYR A O 1 ATOM 81 C CB . TYR A 1 11 ? 87.080 1.860 -24.503 1.00 10.24 ? 11 TYR A CB 1 ATOM 82 C CG . TYR A 1 11 ? 85.864 2.463 -25.180 1.00 10.13 ? 11 TYR A CG 1 ATOM 83 C CD1 . TYR A 1 11 ? 85.900 2.827 -26.522 1.00 8.96 ? 11 TYR A CD1 1 ATOM 84 C CD2 . TYR A 1 11 ? 84.675 2.658 -24.477 1.00 9.55 ? 11 TYR A CD2 1 ATOM 85 C CE1 . TYR A 1 11 ? 84.782 3.370 -27.158 1.00 10.00 ? 11 TYR A CE1 1 ATOM 86 C CE2 . TYR A 1 11 ? 83.549 3.201 -25.103 1.00 9.18 ? 11 TYR A CE2 1 ATOM 87 C CZ . TYR A 1 11 ? 83.611 3.551 -26.441 1.00 8.76 ? 11 TYR A CZ 1 ATOM 88 O OH . TYR A 1 11 ? 82.501 4.066 -27.074 1.00 10.05 ? 11 TYR A OH 1 ATOM 89 N N . LEU A 1 12 ? 88.322 4.932 -25.414 1.00 12.19 ? 12 LEU A N 1 ATOM 90 C CA . LEU A 1 12 ? 88.737 5.728 -26.561 1.00 12.59 ? 12 LEU A CA 1 ATOM 91 C C . LEU A 1 12 ? 90.255 5.730 -26.726 1.00 12.61 ? 12 LEU A C 1 ATOM 92 O O . LEU A 1 12 ? 90.764 6.010 -27.811 1.00 13.10 ? 12 LEU A O 1 ATOM 93 C CB . LEU A 1 12 ? 88.230 7.165 -26.427 1.00 14.14 ? 12 LEU A CB 1 ATOM 94 C CG . LEU A 1 12 ? 86.714 7.340 -26.567 1.00 14.77 ? 12 LEU A CG 1 ATOM 95 C CD1 . LEU A 1 12 ? 86.357 8.810 -26.430 1.00 16.53 ? 12 LEU A CD1 1 ATOM 96 C CD2 . LEU A 1 12 ? 86.254 6.802 -27.918 1.00 13.78 ? 12 LEU A CD2 1 ATOM 97 N N . SER A 1 13 ? 90.971 5.407 -25.651 1.00 12.48 ? 13 SER A N 1 ATOM 98 C CA . SER A 1 13 ? 92.431 5.383 -25.693 1.00 13.74 ? 13 SER A CA 1 ATOM 99 C C . SER A 1 13 ? 92.944 4.332 -26.672 1.00 13.13 ? 13 SER A C 1 ATOM 100 O O . SER A 1 13 ? 94.056 4.450 -27.192 1.00 13.23 ? 13 SER A O 1 ATOM 101 C CB . SER A 1 13 ? 93.005 5.116 -24.299 1.00 14.38 ? 13 SER A CB 1 ATOM 102 O OG . SER A 1 13 ? 92.693 3.811 -23.853 1.00 16.51 ? 13 SER A OG 1 ATOM 103 N N . PHE A 1 14 ? 92.141 3.300 -26.917 1.00 11.50 ? 14 PHE A N 1 ATOM 104 C CA . PHE A 1 14 ? 92.538 2.261 -27.855 1.00 9.82 ? 14 PHE A CA 1 ATOM 105 C C . PHE A 1 14 ? 91.570 2.113 -29.028 1.00 10.14 ? 14 PHE A C 1 ATOM 106 O O . PHE A 1 14 ? 91.448 1.042 -29.620 1.00 10.45 ? 14 PHE A O 1 ATOM 107 C CB . PHE A 1 14 ? 92.754 0.912 -27.134 1.00 10.98 ? 14 PHE A CB 1 ATOM 108 C CG . PHE A 1 14 ? 91.590 0.449 -26.291 1.00 10.82 ? 14 PHE A CG 1 ATOM 109 C CD1 . PHE A 1 14 ? 90.465 -0.123 -26.878 1.00 9.81 ? 14 PHE A CD1 1 ATOM 110 C CD2 . PHE A 1 14 ? 91.648 0.535 -24.903 1.00 11.96 ? 14 PHE A CD2 1 ATOM 111 C CE1 . PHE A 1 14 ? 89.415 -0.610 -26.089 1.00 10.26 ? 14 PHE A CE1 1 ATOM 112 C CE2 . PHE A 1 14 ? 90.605 0.053 -24.107 1.00 12.97 ? 14 PHE A CE2 1 ATOM 113 C CZ . PHE A 1 14 ? 89.488 -0.522 -24.703 1.00 11.51 ? 14 PHE A CZ 1 ATOM 114 N N . ALA A 1 15 ? 90.898 3.209 -29.368 1.00 9.77 ? 15 ALA A N 1 ATOM 115 C CA . ALA A 1 15 ? 89.967 3.220 -30.492 1.00 12.07 ? 15 ALA A CA 1 ATOM 116 C C . ALA A 1 15 ? 90.631 4.004 -31.619 1.00 14.40 ? 15 ALA A C 1 ATOM 117 O O . ALA A 1 15 ? 91.203 5.072 -31.391 1.00 16.44 ? 15 ALA A O 1 ATOM 118 C CB . ALA A 1 15 ? 88.651 3.882 -30.090 1.00 12.55 ? 15 ALA A CB 1 ATOM 119 N N . TYR A 1 16 ? 90.564 3.467 -32.831 1.00 13.45 ? 16 TYR A N 1 ATOM 120 C CA . TYR A 1 16 ? 91.177 4.117 -33.981 1.00 13.98 ? 16 TYR A CA 1 ATOM 121 C C . TYR A 1 16 ? 90.259 4.097 -35.183 1.00 13.67 ? 16 TYR A C 1 ATOM 122 O O . TYR A 1 16 ? 89.394 3.231 -35.302 1.00 12.24 ? 16 TYR A O 1 ATOM 123 C CB . TYR A 1 16 ? 92.470 3.401 -34.379 1.00 15.66 ? 16 TYR A CB 1 ATOM 124 C CG . TYR A 1 16 ? 93.446 3.186 -33.253 1.00 16.85 ? 16 TYR A CG 1 ATOM 125 C CD1 . TYR A 1 16 ? 93.242 2.178 -32.311 1.00 15.53 ? 16 TYR A CD1 1 ATOM 126 C CD2 . TYR A 1 16 ? 94.567 4.004 -33.115 1.00 18.26 ? 16 TYR A CD2 1 ATOM 127 C CE1 . TYR A 1 16 ? 94.130 1.991 -31.255 1.00 17.12 ? 16 TYR A CE1 1 ATOM 128 C CE2 . TYR A 1 16 ? 95.461 3.827 -32.063 1.00 19.75 ? 16 TYR A CE2 1 ATOM 129 C CZ . TYR A 1 16 ? 95.235 2.820 -31.137 1.00 19.69 ? 16 TYR A CZ 1 ATOM 130 O OH . TYR A 1 16 ? 96.105 2.654 -30.083 1.00 22.16 ? 16 TYR A OH 1 ATOM 131 N N . ASP A 1 17 ? 90.451 5.056 -36.079 1.00 14.33 ? 17 ASP A N 1 ATOM 132 C CA . ASP A 1 17 ? 89.671 5.082 -37.303 1.00 14.28 ? 17 ASP A CA 1 ATOM 133 C C . ASP A 1 17 ? 90.422 4.097 -38.189 1.00 14.27 ? 17 ASP A C 1 ATOM 134 O O . ASP A 1 17 ? 91.648 3.999 -38.107 1.00 14.36 ? 17 ASP A O 1 ATOM 135 C CB . ASP A 1 17 ? 89.677 6.478 -37.928 1.00 14.50 ? 17 ASP A CB 1 ATOM 136 C CG . ASP A 1 17 ? 88.802 6.564 -39.165 1.00 14.44 ? 17 ASP A CG 1 ATOM 137 O OD1 . ASP A 1 17 ? 89.205 6.042 -40.225 1.00 15.25 ? 17 ASP A OD1 1 ATOM 138 O OD2 . ASP A 1 17 ? 87.702 7.144 -39.072 1.00 17.70 ? 17 ASP A OD2 1 ATOM 139 N N . ALA A 1 18 ? 89.699 3.351 -39.016 1.00 14.56 ? 18 ALA A N 1 ATOM 140 C CA . ALA A 1 18 ? 90.331 2.364 -39.885 1.00 13.78 ? 18 ALA A CA 1 ATOM 141 C C . ALA A 1 18 ? 91.481 2.944 -40.707 1.00 15.48 ? 18 ALA A C 1 ATOM 142 O O . ALA A 1 18 ? 92.456 2.246 -40.991 1.00 15.19 ? 18 ALA A O 1 ATOM 143 C CB . ALA A 1 18 ? 89.292 1.736 -40.807 1.00 15.08 ? 18 ALA A CB 1 ATOM 144 N N . THR A 1 19 ? 91.370 4.216 -41.084 1.00 15.76 ? 19 THR A N 1 ATOM 145 C CA . THR A 1 19 ? 92.414 4.862 -41.876 1.00 17.66 ? 19 THR A CA 1 ATOM 146 C C . THR A 1 19 ? 93.736 4.936 -41.123 1.00 19.35 ? 19 THR A C 1 ATOM 147 O O . THR A 1 19 ? 94.794 5.101 -41.730 1.00 20.14 ? 19 THR A O 1 ATOM 148 C CB . THR A 1 19 ? 92.022 6.302 -42.281 1.00 16.34 ? 19 THR A CB 1 ATOM 149 O OG1 . THR A 1 19 ? 91.742 7.071 -41.104 1.00 18.24 ? 19 THR A OG1 1 ATOM 150 C CG2 . THR A 1 19 ? 90.807 6.293 -43.189 1.00 16.32 ? 19 THR A CG2 1 ATOM 151 N N . ASP A 1 20 ? 93.609 4.768 -39.899 1.00 20.06 ? 20 ASP A N 1 ATOM 152 C CA . ASP A 1 20 ? 94.787 4.870 -39.048 1.00 20.30 ? 20 ASP A CA 1 ATOM 153 C C . ASP A 1 20 ? 95.355 3.517 -38.625 1.00 20.54 ? 20 ASP A C 1 ATOM 154 O O . ASP A 1 20 ? 96.404 3.454 -37.985 1.00 20.59 ? 20 ASP A O 1 ATOM 155 C CB . ASP A 1 20 ? 94.457 5.723 -37.819 1.00 21.82 ? 20 ASP A CB 1 ATOM 156 C CG . ASP A 1 20 ? 94.310 7.200 -38.160 1.00 24.29 ? 20 ASP A CG 1 ATOM 157 O OD1 . ASP A 1 20 ? 94.691 7.604 -39.278 1.00 25.52 ? 20 ASP A OD1 1 ATOM 158 O OD2 . ASP A 1 20 ? 93.804 7.960 -37.305 1.00 27.40 ? 20 ASP A OD2 1 ATOM 159 N N . LEU A 1 21 ? 94.684 2.457 -38.897 1.00 19.39 ? 21 LEU A N 1 ATOM 160 C CA . LEU A 1 21 ? 95.112 1.100 -38.569 1.00 17.98 ? 21 LEU A CA 1 ATOM 161 C C . LEU A 1 21 ? 96.111 0.619 -39.611 1.00 18.48 ? 21 LEU A C 1 ATOM 162 O O . LEU A 1 21 ? 96.079 1.064 -40.758 1.00 20.41 ? 21 LEU A O 1 ATOM 163 C CB . LEU A 1 21 ? 93.912 0.149 -38.543 1.00 17.00 ? 21 LEU A CB 1 ATOM 164 C CG . LEU A 1 21 ? 92.899 0.365 -37.419 1.00 17.47 ? 21 LEU A CG 1 ATOM 165 C CD1 . LEU A 1 21 ? 91.735 -0.596 -37.591 1.00 16.58 ? 21 LEU A CD1 1 ATOM 166 C CD2 . LEU A 1 21 ? 93.575 0.151 -36.074 1.00 17.82 ? 21 LEU A CD2 1 ATOM 167 N N . GLU A 1 22 ? 96.991 -0.296 -39.215 1.00 19.23 ? 22 GLU A N 1 ATOM 168 C CA . GLU A 1 22 ? 97.993 -0.823 -40.134 1.00 18.69 ? 22 GLU A CA 1 ATOM 169 C C . GLU A 1 22 ? 97.319 -1.496 -41.328 1.00 19.14 ? 22 GLU A C 1 ATOM 170 O O . GLU A 1 22 ? 96.196 -1.991 -41.215 1.00 18.75 ? 22 GLU A O 1 ATOM 171 C CB . GLU A 1 22 ? 98.906 -1.825 -39.412 1.00 19.44 ? 22 GLU A CB 1 ATOM 172 C CG . GLU A 1 22 ? 98.248 -3.135 -38.967 1.00 20.03 ? 22 GLU A CG 1 ATOM 173 C CD . GLU A 1 22 ? 97.196 -2.955 -37.885 1.00 21.54 ? 22 GLU A CD 1 ATOM 174 O OE1 . GLU A 1 22 ? 97.366 -2.070 -37.018 1.00 19.84 ? 22 GLU A OE1 1 ATOM 175 O OE2 . GLU A 1 22 ? 96.204 -3.718 -37.890 1.00 21.97 ? 22 GLU A OE2 1 ATOM 176 N N . LEU A 1 23 ? 98.001 -1.505 -42.472 1.00 17.86 ? 23 LEU A N 1 ATOM 177 C CA . LEU A 1 23 ? 97.458 -2.118 -43.681 1.00 17.30 ? 23 LEU A CA 1 ATOM 178 C C . LEU A 1 23 ? 97.385 -3.635 -43.537 1.00 17.39 ? 23 LEU A C 1 ATOM 179 O O . LEU A 1 23 ? 96.515 -4.280 -44.123 1.00 17.68 ? 23 LEU A O 1 ATOM 180 C CB . LEU A 1 23 ? 98.316 -1.757 -44.896 1.00 19.12 ? 23 LEU A CB 1 ATOM 181 C CG . LEU A 1 23 ? 98.389 -0.276 -45.273 1.00 20.81 ? 23 LEU A CG 1 ATOM 182 C CD1 . LEU A 1 23 ? 99.305 -0.114 -46.479 1.00 21.73 ? 23 LEU A CD1 1 ATOM 183 C CD2 . LEU A 1 23 ? 96.999 0.257 -45.584 1.00 20.54 ? 23 LEU A CD2 1 ATOM 184 N N . GLU A 1 24 ? 98.312 -4.214 -42.757 1.00 15.97 ? 24 GLU A N 1 ATOM 185 C CA . GLU A 1 24 ? 98.334 -5.655 -42.519 1.00 17.50 ? 24 GLU A CA 1 ATOM 186 C C . GLU A 1 24 ? 98.706 -5.930 -41.066 1.00 17.24 ? 24 GLU A C 1 ATOM 187 O O . GLU A 1 24 ? 99.858 -5.748 -40.664 1.00 18.14 ? 24 GLU A O 1 ATOM 188 C CB . GLU A 1 24 ? 99.333 -6.345 -43.450 1.00 19.80 ? 24 GLU A CB 1 ATOM 189 C CG . GLU A 1 24 ? 99.358 -7.860 -43.299 1.00 24.10 ? 24 GLU A CG 1 ATOM 190 C CD . GLU A 1 24 ? 100.316 -8.534 -44.264 1.00 28.47 ? 24 GLU A CD 1 ATOM 191 O OE1 . GLU A 1 24 ? 100.962 -7.816 -45.058 1.00 31.42 ? 24 GLU A OE1 1 ATOM 192 O OE2 . GLU A 1 24 ? 100.430 -9.779 -44.227 1.00 30.37 ? 24 GLU A OE2 1 ATOM 193 N N . GLY A 1 25 ? 97.720 -6.355 -40.297 1.00 14.21 ? 25 GLY A N 1 ATOM 194 C CA . GLY A 1 25 ? 97.958 -6.633 -38.894 1.00 13.59 ? 25 GLY A CA 1 ATOM 195 C C . GLY A 1 25 ? 97.846 -8.099 -38.525 1.00 12.56 ? 25 GLY A C 1 ATOM 196 O O . GLY A 1 25 ? 97.281 -8.901 -39.269 1.00 13.03 ? 25 GLY A O 1 ATOM 197 N N . SER A 1 26 ? 98.391 -8.439 -37.362 1.00 11.81 ? 26 SER A N 1 ATOM 198 C CA . SER A 1 26 ? 98.378 -9.807 -36.854 1.00 12.05 ? 26 SER A CA 1 ATOM 199 C C . SER A 1 26 ? 97.887 -9.795 -35.406 1.00 12.22 ? 26 SER A C 1 ATOM 200 O O . SER A 1 26 ? 98.428 -9.071 -34.573 1.00 12.75 ? 26 SER A O 1 ATOM 201 C CB . SER A 1 26 ? 99.794 -10.387 -36.916 1.00 12.28 ? 26 SER A CB 1 ATOM 202 O OG . SER A 1 26 ? 99.828 -11.716 -36.439 1.00 12.70 ? 26 SER A OG 1 ATOM 203 N N . TYR A 1 27 ? 96.864 -10.596 -35.113 1.00 11.00 ? 27 TYR A N 1 ATOM 204 C CA . TYR A 1 27 ? 96.296 -10.667 -33.765 1.00 9.28 ? 27 TYR A CA 1 ATOM 205 C C . TYR A 1 27 ? 95.951 -12.099 -33.390 1.00 9.61 ? 27 TYR A C 1 ATOM 206 O O . TYR A 1 27 ? 96.106 -13.010 -34.197 1.00 10.66 ? 27 TYR A O 1 ATOM 207 C CB . TYR A 1 27 ? 95.014 -9.831 -33.679 1.00 9.46 ? 27 TYR A CB 1 ATOM 208 C CG . TYR A 1 27 ? 95.188 -8.389 -34.085 1.00 9.42 ? 27 TYR A CG 1 ATOM 209 C CD1 . TYR A 1 27 ? 95.211 -8.021 -35.430 1.00 10.55 ? 27 TYR A CD1 1 ATOM 210 C CD2 . TYR A 1 27 ? 95.365 -7.394 -33.125 1.00 8.66 ? 27 TYR A CD2 1 ATOM 211 C CE1 . TYR A 1 27 ? 95.410 -6.698 -35.807 1.00 11.90 ? 27 TYR A CE1 1 ATOM 212 C CE2 . TYR A 1 27 ? 95.566 -6.067 -33.491 1.00 11.06 ? 27 TYR A CE2 1 ATOM 213 C CZ . TYR A 1 27 ? 95.588 -5.728 -34.832 1.00 11.68 ? 27 TYR A CZ 1 ATOM 214 O OH . TYR A 1 27 ? 95.793 -4.419 -35.203 1.00 14.38 ? 27 TYR A OH 1 ATOM 215 N N . ASP A 1 28 ? 95.490 -12.294 -32.158 1.00 9.27 ? 28 ASP A N 1 ATOM 216 C CA . ASP A 1 28 ? 95.075 -13.620 -31.719 1.00 8.17 ? 28 ASP A CA 1 ATOM 217 C C . ASP A 1 28 ? 93.614 -13.785 -32.126 1.00 9.45 ? 28 ASP A C 1 ATOM 218 O O . ASP A 1 28 ? 93.209 -14.852 -32.589 1.00 9.47 ? 28 ASP A O 1 ATOM 219 C CB . ASP A 1 28 ? 95.207 -13.771 -30.201 1.00 10.21 ? 28 ASP A CB 1 ATOM 220 C CG . ASP A 1 28 ? 96.650 -13.852 -29.748 1.00 10.29 ? 28 ASP A CG 1 ATOM 221 O OD1 . ASP A 1 28 ? 97.383 -14.740 -30.237 1.00 11.82 ? 28 ASP A OD1 1 ATOM 222 O OD2 . ASP A 1 28 ? 97.053 -13.032 -28.899 1.00 11.19 ? 28 ASP A OD2 1 ATOM 223 N N . TYR A 1 29 ? 92.828 -12.724 -31.960 1.00 7.02 ? 29 TYR A N 1 ATOM 224 C CA . TYR A 1 29 ? 91.417 -12.765 -32.330 1.00 8.21 ? 29 TYR A CA 1 ATOM 225 C C . TYR A 1 29 ? 90.976 -11.509 -33.055 1.00 7.30 ? 29 TYR A C 1 ATOM 226 O O . TYR A 1 29 ? 91.403 -10.399 -32.727 1.00 8.74 ? 29 TYR A O 1 ATOM 227 C CB . TYR A 1 29 ? 90.523 -12.954 -31.095 1.00 8.29 ? 29 TYR A CB 1 ATOM 228 C CG . TYR A 1 29 ? 90.788 -14.236 -30.352 1.00 8.30 ? 29 TYR A CG 1 ATOM 229 C CD1 . TYR A 1 29 ? 91.722 -14.282 -29.322 1.00 9.15 ? 29 TYR A CD1 1 ATOM 230 C CD2 . TYR A 1 29 ? 90.154 -15.419 -30.724 1.00 9.36 ? 29 TYR A CD2 1 ATOM 231 C CE1 . TYR A 1 29 ? 92.024 -15.477 -28.681 1.00 8.62 ? 29 TYR A CE1 1 ATOM 232 C CE2 . TYR A 1 29 ? 90.449 -16.623 -30.089 1.00 9.12 ? 29 TYR A CE2 1 ATOM 233 C CZ . TYR A 1 29 ? 91.389 -16.640 -29.070 1.00 8.48 ? 29 TYR A CZ 1 ATOM 234 O OH . TYR A 1 29 ? 91.707 -17.822 -28.454 1.00 9.84 ? 29 TYR A OH 1 ATOM 235 N N . VAL A 1 30 ? 90.127 -11.701 -34.057 1.00 7.81 ? 30 VAL A N 1 ATOM 236 C CA . VAL A 1 30 ? 89.572 -10.595 -34.823 1.00 7.69 ? 30 VAL A CA 1 ATOM 237 C C . VAL A 1 30 ? 88.061 -10.731 -34.708 1.00 8.57 ? 30 VAL A C 1 ATOM 238 O O . VAL A 1 30 ? 87.500 -11.764 -35.067 1.00 8.86 ? 30 VAL A O 1 ATOM 239 C CB . VAL A 1 30 ? 89.976 -10.667 -36.313 1.00 8.20 ? 30 VAL A CB 1 ATOM 240 C CG1 . VAL A 1 30 ? 89.200 -9.625 -37.113 1.00 10.77 ? 30 VAL A CG1 1 ATOM 241 C CG2 . VAL A 1 30 ? 91.478 -10.439 -36.455 1.00 10.56 ? 30 VAL A CG2 1 ATOM 242 N N . ILE A 1 31 ? 87.412 -9.695 -34.187 1.00 8.10 ? 31 ILE A N 1 ATOM 243 C CA . ILE A 1 31 ? 85.965 -9.703 -34.015 1.00 9.30 ? 31 ILE A CA 1 ATOM 244 C C . ILE A 1 31 ? 85.319 -8.773 -35.041 1.00 8.95 ? 31 ILE A C 1 ATOM 245 O O . ILE A 1 31 ? 85.650 -7.587 -35.108 1.00 9.31 ? 31 ILE A O 1 ATOM 246 C CB . ILE A 1 31 ? 85.572 -9.217 -32.593 1.00 10.37 ? 31 ILE A CB 1 ATOM 247 C CG1 . ILE A 1 31 ? 86.322 -10.022 -31.526 1.00 12.80 ? 31 ILE A CG1 1 ATOM 248 C CG2 . ILE A 1 31 ? 84.072 -9.323 -32.401 1.00 11.02 ? 31 ILE A CG2 1 ATOM 249 C CD1 . ILE A 1 31 ? 86.085 -11.511 -31.583 1.00 15.64 ? 31 ILE A CD1 1 ATOM 250 N N . VAL A 1 32 ? 84.402 -9.310 -35.840 1.00 7.28 ? 32 VAL A N 1 ATOM 251 C CA . VAL A 1 32 ? 83.717 -8.504 -36.846 1.00 7.40 ? 32 VAL A CA 1 ATOM 252 C C . VAL A 1 32 ? 82.409 -7.992 -36.260 1.00 6.87 ? 32 VAL A C 1 ATOM 253 O O . VAL A 1 32 ? 81.494 -8.771 -35.979 1.00 7.44 ? 32 VAL A O 1 ATOM 254 C CB . VAL A 1 32 ? 83.410 -9.323 -38.121 1.00 4.99 ? 32 VAL A CB 1 ATOM 255 C CG1 . VAL A 1 32 ? 82.723 -8.434 -39.159 1.00 8.07 ? 32 VAL A CG1 1 ATOM 256 C CG2 . VAL A 1 32 ? 84.699 -9.900 -38.684 1.00 7.65 ? 32 VAL A CG2 1 ATOM 257 N N . GLY A 1 33 ? 82.330 -6.678 -36.067 1.00 7.23 ? 33 GLY A N 1 ATOM 258 C CA . GLY A 1 33 ? 81.132 -6.081 -35.507 1.00 7.13 ? 33 GLY A CA 1 ATOM 259 C C . GLY A 1 33 ? 81.292 -5.780 -34.027 1.00 8.22 ? 33 GLY A C 1 ATOM 260 O O . GLY A 1 33 ? 81.279 -6.690 -33.200 1.00 9.03 ? 33 GLY A O 1 ATOM 261 N N . GLY A 1 34 ? 81.454 -4.503 -33.693 1.00 7.29 ? 34 GLY A N 1 ATOM 262 C CA . GLY A 1 34 ? 81.603 -4.121 -32.301 1.00 6.11 ? 34 GLY A CA 1 ATOM 263 C C . GLY A 1 34 ? 80.234 -3.812 -31.736 1.00 6.95 ? 34 GLY A C 1 ATOM 264 O O . GLY A 1 34 ? 79.961 -2.688 -31.308 1.00 7.62 ? 34 GLY A O 1 ATOM 265 N N . GLY A 1 35 ? 79.367 -4.820 -31.744 1.00 7.28 ? 35 GLY A N 1 ATOM 266 C CA . GLY A 1 35 ? 78.011 -4.635 -31.263 1.00 6.39 ? 35 GLY A CA 1 ATOM 267 C C . GLY A 1 35 ? 77.705 -5.147 -29.871 1.00 6.42 ? 35 GLY A C 1 ATOM 268 O O . GLY A 1 35 ? 78.587 -5.256 -29.016 1.00 6.58 ? 35 GLY A O 1 ATOM 269 N N . THR A 1 36 ? 76.433 -5.476 -29.663 1.00 6.12 ? 36 THR A N 1 ATOM 270 C CA . THR A 1 36 ? 75.920 -5.966 -28.393 1.00 6.12 ? 36 THR A CA 1 ATOM 271 C C . THR A 1 36 ? 76.697 -7.174 -27.870 1.00 6.26 ? 36 THR A C 1 ATOM 272 O O . THR A 1 36 ? 77.137 -7.175 -26.721 1.00 7.52 ? 36 THR A O 1 ATOM 273 C CB . THR A 1 36 ? 74.422 -6.303 -28.530 1.00 7.29 ? 36 THR A CB 1 ATOM 274 O OG1 . THR A 1 36 ? 73.736 -5.159 -29.062 1.00 6.54 ? 36 THR A OG1 1 ATOM 275 C CG2 . THR A 1 36 ? 73.818 -6.650 -27.177 1.00 6.60 ? 36 THR A CG2 1 ATOM 276 N N . SER A 1 37 ? 76.870 -8.197 -28.702 1.00 6.77 ? 37 SER A N 1 ATOM 277 C CA . SER A 1 37 ? 77.634 -9.374 -28.286 1.00 6.29 ? 37 SER A CA 1 ATOM 278 C C . SER A 1 37 ? 79.131 -9.173 -28.532 1.00 6.05 ? 37 SER A C 1 ATOM 279 O O . SER A 1 37 ? 79.964 -9.593 -27.729 1.00 6.96 ? 37 SER A O 1 ATOM 280 C CB . SER A 1 37 ? 77.184 -10.626 -29.052 1.00 5.19 ? 37 SER A CB 1 ATOM 281 O OG . SER A 1 37 ? 75.867 -11.023 -28.712 1.00 6.78 ? 37 SER A OG 1 ATOM 282 N N . GLY A 1 38 ? 79.460 -8.529 -29.649 1.00 5.87 ? 38 GLY A N 1 ATOM 283 C CA . GLY A 1 38 ? 80.850 -8.308 -30.013 1.00 5.92 ? 38 GLY A CA 1 ATOM 284 C C . GLY A 1 38 ? 81.732 -7.585 -29.009 1.00 7.06 ? 38 GLY A C 1 ATOM 285 O O . GLY A 1 38 ? 82.880 -7.977 -28.801 1.00 7.19 ? 38 GLY A O 1 ATOM 286 N N . CYS A 1 39 ? 81.216 -6.528 -28.392 1.00 7.61 ? 39 CYS A N 1 ATOM 287 C CA . CYS A 1 39 ? 82.015 -5.774 -27.428 1.00 7.57 ? 39 CYS A CA 1 ATOM 288 C C . CYS A 1 39 ? 82.413 -6.586 -26.190 1.00 8.66 ? 39 CYS A C 1 ATOM 289 O O . CYS A 1 39 ? 83.597 -6.667 -25.858 1.00 8.88 ? 39 CYS A O 1 ATOM 290 C CB . CYS A 1 39 ? 81.280 -4.488 -27.032 1.00 8.90 ? 39 CYS A CB 1 ATOM 291 S SG . CYS A 1 39 ? 81.274 -3.249 -28.361 1.00 9.78 ? 39 CYS A SG 1 ATOM 292 N N . PRO A 1 40 ? 81.442 -7.191 -25.484 1.00 7.50 ? 40 PRO A N 1 ATOM 293 C CA . PRO A 1 40 ? 81.834 -7.974 -24.305 1.00 8.56 ? 40 PRO A CA 1 ATOM 294 C C . PRO A 1 40 ? 82.698 -9.186 -24.663 1.00 8.94 ? 40 PRO A C 1 ATOM 295 O O . PRO A 1 40 ? 83.520 -9.627 -23.861 1.00 8.26 ? 40 PRO A O 1 ATOM 296 C CB . PRO A 1 40 ? 80.495 -8.355 -23.665 1.00 7.85 ? 40 PRO A CB 1 ATOM 297 C CG . PRO A 1 40 ? 79.508 -8.264 -24.811 1.00 6.31 ? 40 PRO A CG 1 ATOM 298 C CD . PRO A 1 40 ? 79.977 -7.053 -25.564 1.00 7.89 ? 40 PRO A CD 1 ATOM 299 N N . LEU A 1 41 ? 82.508 -9.721 -25.864 1.00 8.34 ? 41 LEU A N 1 ATOM 300 C CA . LEU A 1 41 ? 83.311 -10.851 -26.326 1.00 8.77 ? 41 LEU A CA 1 ATOM 301 C C . LEU A 1 41 ? 84.756 -10.376 -26.480 1.00 9.26 ? 41 LEU A C 1 ATOM 302 O O . LEU A 1 41 ? 85.692 -11.009 -25.992 1.00 9.36 ? 41 LEU A O 1 ATOM 303 C CB . LEU A 1 41 ? 82.798 -11.354 -27.681 1.00 8.65 ? 41 LEU A CB 1 ATOM 304 C CG . LEU A 1 41 ? 83.708 -12.339 -28.427 1.00 10.16 ? 41 LEU A CG 1 ATOM 305 C CD1 . LEU A 1 41 ? 83.838 -13.646 -27.642 1.00 9.62 ? 41 LEU A CD1 1 ATOM 306 C CD2 . LEU A 1 41 ? 83.132 -12.599 -29.811 1.00 9.57 ? 41 LEU A CD2 1 ATOM 307 N N . ALA A 1 42 ? 84.927 -9.249 -27.161 1.00 8.81 ? 42 ALA A N 1 ATOM 308 C CA . ALA A 1 42 ? 86.251 -8.684 -27.388 1.00 9.03 ? 42 ALA A CA 1 ATOM 309 C C . ALA A 1 42 ? 86.962 -8.350 -26.078 1.00 9.97 ? 42 ALA A C 1 ATOM 310 O O . ALA A 1 42 ? 88.137 -8.672 -25.895 1.00 10.46 ? 42 ALA A O 1 ATOM 311 C CB . ALA A 1 42 ? 86.131 -7.438 -28.244 1.00 10.03 ? 42 ALA A CB 1 ATOM 312 N N . ALA A 1 43 ? 86.253 -7.692 -25.170 1.00 8.10 ? 43 ALA A N 1 ATOM 313 C CA . ALA A 1 43 ? 86.840 -7.319 -23.890 1.00 8.71 ? 43 ALA A CA 1 ATOM 314 C C . ALA A 1 43 ? 87.304 -8.553 -23.123 1.00 8.67 ? 43 ALA A C 1 ATOM 315 O O . ALA A 1 43 ? 88.403 -8.576 -22.565 1.00 8.73 ? 43 ALA A O 1 ATOM 316 C CB . ALA A 1 43 ? 85.829 -6.537 -23.060 1.00 7.30 ? 43 ALA A CB 1 ATOM 317 N N . THR A 1 44 ? 86.466 -9.583 -23.106 1.00 7.99 ? 44 THR A N 1 ATOM 318 C CA . THR A 1 44 ? 86.794 -10.811 -22.398 1.00 8.37 ? 44 THR A CA 1 ATOM 319 C C . THR A 1 44 ? 88.049 -11.474 -22.957 1.00 9.68 ? 44 THR A C 1 ATOM 320 O O . THR A 1 44 ? 88.966 -11.814 -22.208 1.00 9.40 ? 44 THR A O 1 ATOM 321 C CB . THR A 1 44 ? 85.609 -11.789 -22.452 1.00 9.54 ? 44 THR A CB 1 ATOM 322 O OG1 . THR A 1 44 ? 84.491 -11.203 -21.773 1.00 8.12 ? 44 THR A OG1 1 ATOM 323 C CG2 . THR A 1 44 ? 85.964 -13.111 -21.784 1.00 10.59 ? 44 THR A CG2 1 ATOM 324 N N . LEU A 1 45 ? 88.095 -11.652 -24.272 1.00 7.16 ? 45 LEU A N 1 ATOM 325 C CA . LEU A 1 45 ? 89.259 -12.268 -24.895 1.00 8.16 ? 45 LEU A CA 1 ATOM 326 C C . LEU A 1 45 ? 90.527 -11.451 -24.651 1.00 9.65 ? 45 LEU A C 1 ATOM 327 O O . LEU A 1 45 ? 91.603 -12.019 -24.479 1.00 9.46 ? 45 LEU A O 1 ATOM 328 C CB . LEU A 1 45 ? 89.034 -12.435 -26.402 1.00 6.93 ? 45 LEU A CB 1 ATOM 329 C CG . LEU A 1 45 ? 88.007 -13.496 -26.811 1.00 6.52 ? 45 LEU A CG 1 ATOM 330 C CD1 . LEU A 1 45 ? 87.747 -13.410 -28.304 1.00 8.16 ? 45 LEU A CD1 1 ATOM 331 C CD2 . LEU A 1 45 ? 88.508 -14.881 -26.430 1.00 9.09 ? 45 LEU A CD2 1 ATOM 332 N N . SER A 1 46 ? 90.398 -10.124 -24.619 1.00 9.65 ? 46 SER A N 1 ATOM 333 C CA . SER A 1 46 ? 91.560 -9.255 -24.423 1.00 9.80 ? 46 SER A CA 1 ATOM 334 C C . SER A 1 46 ? 92.197 -9.393 -23.043 1.00 10.00 ? 46 SER A C 1 ATOM 335 O O . SER A 1 46 ? 93.291 -8.881 -22.807 1.00 10.34 ? 46 SER A O 1 ATOM 336 C CB . SER A 1 46 ? 91.188 -7.784 -24.670 1.00 9.14 ? 46 SER A CB 1 ATOM 337 O OG . SER A 1 46 ? 90.481 -7.226 -23.575 1.00 9.37 ? 46 SER A OG 1 ATOM 338 N N . GLU A 1 47 ? 91.517 -10.075 -22.128 1.00 10.32 ? 47 GLU A N 1 ATOM 339 C CA . GLU A 1 47 ? 92.067 -10.264 -20.793 1.00 11.23 ? 47 GLU A CA 1 ATOM 340 C C . GLU A 1 47 ? 93.382 -11.034 -20.875 1.00 11.92 ? 47 GLU A C 1 ATOM 341 O O . GLU A 1 47 ? 94.265 -10.872 -20.026 1.00 12.85 ? 47 GLU A O 1 ATOM 342 C CB . GLU A 1 47 ? 91.070 -11.019 -19.910 1.00 13.27 ? 47 GLU A CB 1 ATOM 343 C CG . GLU A 1 47 ? 89.896 -10.165 -19.443 1.00 15.70 ? 47 GLU A CG 1 ATOM 344 C CD . GLU A 1 47 ? 88.891 -10.948 -18.621 1.00 18.72 ? 47 GLU A CD 1 ATOM 345 O OE1 . GLU A 1 47 ? 89.314 -11.854 -17.871 1.00 20.87 ? 47 GLU A OE1 1 ATOM 346 O OE2 . GLU A 1 47 ? 87.680 -10.651 -18.709 1.00 18.21 ? 47 GLU A OE2 1 ATOM 347 N N . LYS A 1 48 ? 93.519 -11.855 -21.912 1.00 11.35 ? 48 LYS A N 1 ATOM 348 C CA . LYS A 1 48 ? 94.722 -12.660 -22.095 1.00 11.20 ? 48 LYS A CA 1 ATOM 349 C C . LYS A 1 48 ? 95.367 -12.566 -23.475 1.00 11.62 ? 48 LYS A C 1 ATOM 350 O O . LYS A 1 48 ? 96.581 -12.744 -23.607 1.00 11.40 ? 48 LYS A O 1 ATOM 351 C CB . LYS A 1 48 ? 94.410 -14.131 -21.806 1.00 12.21 ? 48 LYS A CB 1 ATOM 352 C CG . LYS A 1 48 ? 94.119 -14.439 -20.348 1.00 18.48 ? 48 LYS A CG 1 ATOM 353 C CD . LYS A 1 48 ? 93.771 -15.908 -20.166 1.00 22.98 ? 48 LYS A CD 1 ATOM 354 C CE . LYS A 1 48 ? 93.807 -16.310 -18.699 1.00 26.11 ? 48 LYS A CE 1 ATOM 355 N NZ . LYS A 1 48 ? 92.956 -15.437 -17.849 1.00 29.23 ? 48 LYS A NZ 1 ATOM 356 N N . TYR A 1 49 ? 94.569 -12.285 -24.502 1.00 10.37 ? 49 TYR A N 1 ATOM 357 C CA . TYR A 1 49 ? 95.105 -12.239 -25.858 1.00 9.56 ? 49 TYR A CA 1 ATOM 358 C C . TYR A 1 49 ? 94.938 -10.925 -26.610 1.00 9.40 ? 49 TYR A C 1 ATOM 359 O O . TYR A 1 49 ? 94.202 -10.039 -26.179 1.00 9.41 ? 49 TYR A O 1 ATOM 360 C CB . TYR A 1 49 ? 94.500 -13.386 -26.674 1.00 10.47 ? 49 TYR A CB 1 ATOM 361 C CG . TYR A 1 49 ? 94.845 -14.752 -26.123 1.00 11.82 ? 49 TYR A CG 1 ATOM 362 C CD1 . TYR A 1 49 ? 93.938 -15.466 -25.336 1.00 13.46 ? 49 TYR A CD1 1 ATOM 363 C CD2 . TYR A 1 49 ? 96.094 -15.318 -26.367 1.00 14.28 ? 49 TYR A CD2 1 ATOM 364 C CE1 . TYR A 1 49 ? 94.274 -16.718 -24.806 1.00 14.57 ? 49 TYR A CE1 1 ATOM 365 C CE2 . TYR A 1 49 ? 96.440 -16.559 -25.842 1.00 15.22 ? 49 TYR A CE2 1 ATOM 366 C CZ . TYR A 1 49 ? 95.529 -17.254 -25.066 1.00 15.23 ? 49 TYR A CZ 1 ATOM 367 O OH . TYR A 1 49 ? 95.884 -18.486 -24.559 1.00 17.38 ? 49 TYR A OH 1 ATOM 368 N N . LYS A 1 50 ? 95.638 -10.812 -27.740 1.00 9.27 ? 50 LYS A N 1 ATOM 369 C CA . LYS A 1 50 ? 95.589 -9.613 -28.573 1.00 7.31 ? 50 LYS A CA 1 ATOM 370 C C . LYS A 1 50 ? 94.349 -9.670 -29.450 1.00 8.82 ? 50 LYS A C 1 ATOM 371 O O . LYS A 1 50 ? 94.192 -10.574 -30.271 1.00 8.80 ? 50 LYS A O 1 ATOM 372 C CB . LYS A 1 50 ? 96.849 -9.519 -29.432 1.00 8.38 ? 50 LYS A CB 1 ATOM 373 C CG . LYS A 1 50 ? 98.137 -9.442 -28.616 1.00 9.24 ? 50 LYS A CG 1 ATOM 374 C CD . LYS A 1 50 ? 98.217 -8.152 -27.816 1.00 9.26 ? 50 LYS A CD 1 ATOM 375 C CE . LYS A 1 50 ? 99.509 -8.090 -27.008 1.00 10.72 ? 50 LYS A CE 1 ATOM 376 N NZ . LYS A 1 50 ? 99.642 -6.794 -26.281 1.00 10.15 ? 50 LYS A NZ 1 ATOM 377 N N . VAL A 1 51 ? 93.481 -8.680 -29.274 1.00 8.73 ? 51 VAL A N 1 ATOM 378 C CA . VAL A 1 51 ? 92.218 -8.625 -29.992 1.00 9.37 ? 51 VAL A CA 1 ATOM 379 C C . VAL A 1 51 ? 92.016 -7.356 -30.802 1.00 9.79 ? 51 VAL A C 1 ATOM 380 O O . VAL A 1 51 ? 92.405 -6.267 -30.381 1.00 9.56 ? 51 VAL A O 1 ATOM 381 C CB . VAL A 1 51 ? 91.042 -8.740 -28.989 1.00 8.40 ? 51 VAL A CB 1 ATOM 382 C CG1 . VAL A 1 51 ? 89.712 -8.734 -29.727 1.00 8.75 ? 51 VAL A CG1 1 ATOM 383 C CG2 . VAL A 1 51 ? 91.194 -10.001 -28.151 1.00 8.74 ? 51 VAL A CG2 1 ATOM 384 N N . LEU A 1 52 ? 91.404 -7.514 -31.972 1.00 8.70 ? 52 LEU A N 1 ATOM 385 C CA . LEU A 1 52 ? 91.076 -6.389 -32.832 1.00 8.66 ? 52 LEU A CA 1 ATOM 386 C C . LEU A 1 52 ? 89.588 -6.489 -33.133 1.00 9.37 ? 52 LEU A C 1 ATOM 387 O O . LEU A 1 52 ? 89.109 -7.533 -33.574 1.00 8.29 ? 52 LEU A O 1 ATOM 388 C CB . LEU A 1 52 ? 91.851 -6.438 -34.153 1.00 8.27 ? 52 LEU A CB 1 ATOM 389 C CG . LEU A 1 52 ? 91.430 -5.343 -35.144 1.00 8.88 ? 52 LEU A CG 1 ATOM 390 C CD1 . LEU A 1 52 ? 91.803 -3.978 -34.577 1.00 10.03 ? 52 LEU A CD1 1 ATOM 391 C CD2 . LEU A 1 52 ? 92.094 -5.561 -36.499 1.00 10.44 ? 52 LEU A CD2 1 ATOM 392 N N . VAL A 1 53 ? 88.859 -5.413 -32.862 1.00 9.85 ? 53 VAL A N 1 ATOM 393 C CA . VAL A 1 53 ? 87.430 -5.358 -33.145 1.00 10.54 ? 53 VAL A CA 1 ATOM 394 C C . VAL A 1 53 ? 87.284 -4.408 -34.323 1.00 10.59 ? 53 VAL A C 1 ATOM 395 O O . VAL A 1 53 ? 87.887 -3.331 -34.333 1.00 12.77 ? 53 VAL A O 1 ATOM 396 C CB . VAL A 1 53 ? 86.624 -4.776 -31.970 1.00 13.55 ? 53 VAL A CB 1 ATOM 397 C CG1 . VAL A 1 53 ? 85.142 -4.737 -32.327 1.00 14.64 ? 53 VAL A CG1 1 ATOM 398 C CG2 . VAL A 1 53 ? 86.852 -5.595 -30.725 1.00 15.42 ? 53 VAL A CG2 1 ATOM 399 N N . LEU A 1 54 ? 86.489 -4.805 -35.310 1.00 8.07 ? 54 LEU A N 1 ATOM 400 C CA . LEU A 1 54 ? 86.266 -3.981 -36.494 1.00 8.36 ? 54 LEU A CA 1 ATOM 401 C C . LEU A 1 54 ? 84.784 -3.641 -36.613 1.00 8.89 ? 54 LEU A C 1 ATOM 402 O O . LEU A 1 54 ? 83.949 -4.523 -36.817 1.00 8.61 ? 54 LEU A O 1 ATOM 403 C CB . LEU A 1 54 ? 86.746 -4.721 -37.745 1.00 9.00 ? 54 LEU A CB 1 ATOM 404 C CG . LEU A 1 54 ? 88.251 -5.009 -37.792 1.00 9.99 ? 54 LEU A CG 1 ATOM 405 C CD1 . LEU A 1 54 ? 88.549 -6.019 -38.889 1.00 11.71 ? 54 LEU A CD1 1 ATOM 406 C CD2 . LEU A 1 54 ? 89.012 -3.710 -38.029 1.00 10.96 ? 54 LEU A CD2 1 ATOM 407 N N . GLU A 1 55 ? 84.470 -2.354 -36.493 1.00 7.11 ? 55 GLU A N 1 ATOM 408 C CA . GLU A 1 55 ? 83.093 -1.867 -36.556 1.00 9.34 ? 55 GLU A CA 1 ATOM 409 C C . GLU A 1 55 ? 82.908 -0.900 -37.718 1.00 8.68 ? 55 GLU A C 1 ATOM 410 O O . GLU A 1 55 ? 83.670 0.050 -37.862 1.00 8.82 ? 55 GLU A O 1 ATOM 411 C CB . GLU A 1 55 ? 82.750 -1.166 -35.237 1.00 9.46 ? 55 GLU A CB 1 ATOM 412 C CG . GLU A 1 55 ? 81.465 -0.349 -35.251 1.00 8.82 ? 55 GLU A CG 1 ATOM 413 C CD . GLU A 1 55 ? 80.256 -1.170 -35.633 1.00 9.34 ? 55 GLU A CD 1 ATOM 414 O OE1 . GLU A 1 55 ? 80.139 -2.306 -35.131 1.00 8.69 ? 55 GLU A OE1 1 ATOM 415 O OE2 . GLU A 1 55 ? 79.422 -0.677 -36.424 1.00 8.38 ? 55 GLU A OE2 1 ATOM 416 N N . ARG A 1 56 ? 81.885 -1.136 -38.534 1.00 8.09 ? 56 ARG A N 1 ATOM 417 C CA . ARG A 1 56 ? 81.619 -0.286 -39.691 1.00 8.51 ? 56 ARG A CA 1 ATOM 418 C C . ARG A 1 56 ? 81.146 1.121 -39.326 1.00 8.35 ? 56 ARG A C 1 ATOM 419 O O . ARG A 1 56 ? 81.403 2.072 -40.066 1.00 9.00 ? 56 ARG A O 1 ATOM 420 C CB . ARG A 1 56 ? 80.574 -0.948 -40.595 1.00 7.83 ? 56 ARG A CB 1 ATOM 421 C CG . ARG A 1 56 ? 79.240 -1.157 -39.907 1.00 7.40 ? 56 ARG A CG 1 ATOM 422 C CD . ARG A 1 56 ? 78.177 -1.721 -40.834 1.00 7.21 ? 56 ARG A CD 1 ATOM 423 N NE . ARG A 1 56 ? 76.896 -1.754 -40.135 1.00 6.96 ? 56 ARG A NE 1 ATOM 424 C CZ . ARG A 1 56 ? 75.706 -1.817 -40.723 1.00 4.71 ? 56 ARG A CZ 1 ATOM 425 N NH1 . ARG A 1 56 ? 75.605 -1.866 -42.047 1.00 6.11 ? 56 ARG A NH1 1 ATOM 426 N NH2 . ARG A 1 56 ? 74.612 -1.790 -39.976 1.00 6.16 ? 56 ARG A NH2 1 ATOM 427 N N . GLY A 1 57 ? 80.457 1.252 -38.194 1.00 8.66 ? 57 GLY A N 1 ATOM 428 C CA . GLY A 1 57 ? 79.951 2.552 -37.776 1.00 9.47 ? 57 GLY A CA 1 ATOM 429 C C . GLY A 1 57 ? 80.928 3.460 -37.045 1.00 9.50 ? 57 GLY A C 1 ATOM 430 O O . GLY A 1 57 ? 82.099 3.124 -36.866 1.00 10.51 ? 57 GLY A O 1 ATOM 431 N N . SER A 1 58 ? 80.432 4.620 -36.617 1.00 9.09 ? 58 SER A N 1 ATOM 432 C CA . SER A 1 58 ? 81.244 5.605 -35.899 1.00 10.07 ? 58 SER A CA 1 ATOM 433 C C . SER A 1 58 ? 81.254 5.372 -34.391 1.00 9.64 ? 58 SER A C 1 ATOM 434 O O . SER A 1 58 ? 80.618 4.451 -33.881 1.00 9.61 ? 58 SER A O 1 ATOM 435 C CB . SER A 1 58 ? 80.701 7.020 -36.147 1.00 10.03 ? 58 SER A CB 1 ATOM 436 O OG . SER A 1 58 ? 80.596 7.321 -37.525 1.00 12.04 ? 58 SER A OG 1 ATOM 437 N N . LEU A 1 59 ? 81.996 6.215 -33.680 1.00 11.03 ? 59 LEU A N 1 ATOM 438 C CA . LEU A 1 59 ? 82.042 6.154 -32.225 1.00 10.96 ? 59 LEU A CA 1 ATOM 439 C C . LEU A 1 59 ? 80.728 6.800 -31.786 1.00 11.18 ? 59 LEU A C 1 ATOM 440 O O . LEU A 1 59 ? 80.166 7.623 -32.515 1.00 11.65 ? 59 LEU A O 1 ATOM 441 C CB . LEU A 1 59 ? 83.219 6.977 -31.689 1.00 12.53 ? 59 LEU A CB 1 ATOM 442 C CG . LEU A 1 59 ? 84.634 6.497 -32.021 1.00 14.37 ? 59 LEU A CG 1 ATOM 443 C CD1 . LEU A 1 59 ? 85.641 7.584 -31.670 1.00 16.16 ? 59 LEU A CD1 1 ATOM 444 C CD2 . LEU A 1 59 ? 84.935 5.222 -31.253 1.00 15.08 ? 59 LEU A CD2 1 ATOM 445 N N . PRO A 1 60 ? 80.212 6.433 -30.603 1.00 11.00 ? 60 PRO A N 1 ATOM 446 C CA . PRO A 1 60 ? 78.953 7.028 -30.142 1.00 11.15 ? 60 PRO A CA 1 ATOM 447 C C . PRO A 1 60 ? 79.056 8.549 -30.008 1.00 11.14 ? 60 PRO A C 1 ATOM 448 O O . PRO A 1 60 ? 78.060 9.262 -30.119 1.00 11.04 ? 60 PRO A O 1 ATOM 449 C CB . PRO A 1 60 ? 78.722 6.348 -28.794 1.00 10.83 ? 60 PRO A CB 1 ATOM 450 C CG . PRO A 1 60 ? 79.366 5.004 -28.978 1.00 11.26 ? 60 PRO A CG 1 ATOM 451 C CD . PRO A 1 60 ? 80.652 5.364 -29.690 1.00 11.75 ? 60 PRO A CD 1 ATOM 452 N N . THR A 1 61 ? 80.268 9.037 -29.771 1.00 10.55 ? 61 THR A N 1 ATOM 453 C CA . THR A 1 61 ? 80.488 10.471 -29.614 1.00 12.36 ? 61 THR A CA 1 ATOM 454 C C . THR A 1 61 ? 80.175 11.275 -30.878 1.00 12.94 ? 61 THR A C 1 ATOM 455 O O . THR A 1 61 ? 79.944 12.485 -30.807 1.00 13.83 ? 61 THR A O 1 ATOM 456 C CB . THR A 1 61 ? 81.939 10.761 -29.182 1.00 12.35 ? 61 THR A CB 1 ATOM 457 O OG1 . THR A 1 61 ? 82.846 10.126 -30.090 1.00 13.87 ? 61 THR A OG1 1 ATOM 458 C CG2 . THR A 1 61 ? 82.190 10.237 -27.773 1.00 14.57 ? 61 THR A CG2 1 ATOM 459 N N . ALA A 1 62 ? 80.166 10.608 -32.030 1.00 12.61 ? 62 ALA A N 1 ATOM 460 C CA . ALA A 1 62 ? 79.874 11.276 -33.296 1.00 12.29 ? 62 ALA A CA 1 ATOM 461 C C . ALA A 1 62 ? 78.392 11.622 -33.419 1.00 12.55 ? 62 ALA A C 1 ATOM 462 O O . ALA A 1 62 ? 78.006 12.459 -34.239 1.00 12.77 ? 62 ALA A O 1 ATOM 463 C CB . ALA A 1 62 ? 80.296 10.397 -34.460 1.00 13.53 ? 62 ALA A CB 1 ATOM 464 N N . TYR A 1 63 ? 77.566 10.969 -32.606 1.00 12.03 ? 63 TYR A N 1 ATOM 465 C CA . TYR A 1 63 ? 76.126 11.209 -32.619 1.00 12.88 ? 63 TYR A CA 1 ATOM 466 C C . TYR A 1 63 ? 75.620 11.288 -31.182 1.00 13.75 ? 63 TYR A C 1 ATOM 467 O O . TYR A 1 63 ? 75.035 10.342 -30.658 1.00 12.21 ? 63 TYR A O 1 ATOM 468 C CB . TYR A 1 63 ? 75.411 10.090 -33.384 1.00 11.85 ? 63 TYR A CB 1 ATOM 469 C CG . TYR A 1 63 ? 75.826 10.010 -34.833 1.00 10.60 ? 63 TYR A CG 1 ATOM 470 C CD1 . TYR A 1 63 ? 76.916 9.236 -35.227 1.00 9.84 ? 63 TYR A CD1 1 ATOM 471 C CD2 . TYR A 1 63 ? 75.159 10.753 -35.806 1.00 11.74 ? 63 TYR A CD2 1 ATOM 472 C CE1 . TYR A 1 63 ? 77.336 9.205 -36.557 1.00 9.23 ? 63 TYR A CE1 1 ATOM 473 C CE2 . TYR A 1 63 ? 75.570 10.732 -37.136 1.00 10.15 ? 63 TYR A CE2 1 ATOM 474 C CZ . TYR A 1 63 ? 76.660 9.958 -37.505 1.00 9.91 ? 63 TYR A CZ 1 ATOM 475 O OH . TYR A 1 63 ? 77.075 9.954 -38.818 1.00 11.81 ? 63 TYR A OH 1 ATOM 476 N N . PRO A 1 64 ? 75.831 12.442 -30.533 1.00 13.73 ? 64 PRO A N 1 ATOM 477 C CA . PRO A 1 64 ? 75.444 12.738 -29.151 1.00 14.14 ? 64 PRO A CA 1 ATOM 478 C C . PRO A 1 64 ? 74.072 12.262 -28.681 1.00 13.43 ? 64 PRO A C 1 ATOM 479 O O . PRO A 1 64 ? 73.919 11.865 -27.528 1.00 14.48 ? 64 PRO A O 1 ATOM 480 C CB . PRO A 1 64 ? 75.575 14.256 -29.080 1.00 15.71 ? 64 PRO A CB 1 ATOM 481 C CG . PRO A 1 64 ? 76.715 14.523 -29.997 1.00 15.94 ? 64 PRO A CG 1 ATOM 482 C CD . PRO A 1 64 ? 76.391 13.644 -31.180 1.00 15.53 ? 64 PRO A CD 1 ATOM 483 N N . ASN A 1 65 ? 73.077 12.298 -29.560 1.00 13.21 ? 65 ASN A N 1 ATOM 484 C CA . ASN A 1 65 ? 71.739 11.887 -29.161 1.00 12.85 ? 65 ASN A CA 1 ATOM 485 C C . ASN A 1 65 ? 71.528 10.397 -28.906 1.00 12.97 ? 65 ASN A C 1 ATOM 486 O O . ASN A 1 65 ? 70.438 9.984 -28.513 1.00 11.07 ? 65 ASN A O 1 ATOM 487 C CB . ASN A 1 65 ? 70.709 12.420 -30.158 1.00 15.23 ? 65 ASN A CB 1 ATOM 488 C CG . ASN A 1 65 ? 70.569 13.929 -30.079 1.00 16.68 ? 65 ASN A CG 1 ATOM 489 O OD1 . ASN A 1 65 ? 70.424 14.487 -28.992 1.00 17.89 ? 65 ASN A OD1 1 ATOM 490 N ND2 . ASN A 1 65 ? 70.614 14.595 -31.225 1.00 17.13 ? 65 ASN A ND2 1 ATOM 491 N N . VAL A 1 66 ? 72.557 9.584 -29.120 1.00 12.03 ? 66 VAL A N 1 ATOM 492 C CA . VAL A 1 66 ? 72.416 8.159 -28.830 1.00 11.21 ? 66 VAL A CA 1 ATOM 493 C C . VAL A 1 66 ? 72.814 7.958 -27.370 1.00 11.16 ? 66 VAL A C 1 ATOM 494 O O . VAL A 1 66 ? 72.766 6.845 -26.849 1.00 12.58 ? 66 VAL A O 1 ATOM 495 C CB . VAL A 1 66 ? 73.340 7.271 -29.712 1.00 10.65 ? 66 VAL A CB 1 ATOM 496 C CG1 . VAL A 1 66 ? 73.030 7.482 -31.184 1.00 9.49 ? 66 VAL A CG1 1 ATOM 497 C CG2 . VAL A 1 66 ? 74.810 7.576 -29.417 1.00 12.92 ? 66 VAL A CG2 1 ATOM 498 N N . LEU A 1 67 ? 73.192 9.047 -26.706 1.00 10.75 ? 67 LEU A N 1 ATOM 499 C CA . LEU A 1 67 ? 73.641 8.972 -25.319 1.00 10.99 ? 67 LEU A CA 1 ATOM 500 C C . LEU A 1 67 ? 72.636 9.376 -24.242 1.00 10.32 ? 67 LEU A C 1 ATOM 501 O O . LEU A 1 67 ? 72.983 9.430 -23.063 1.00 12.10 ? 67 LEU A O 1 ATOM 502 C CB . LEU A 1 67 ? 74.923 9.794 -25.162 1.00 11.26 ? 67 LEU A CB 1 ATOM 503 C CG . LEU A 1 67 ? 76.078 9.375 -26.080 1.00 12.94 ? 67 LEU A CG 1 ATOM 504 C CD1 . LEU A 1 67 ? 77.254 10.330 -25.917 1.00 13.94 ? 67 LEU A CD1 1 ATOM 505 C CD2 . LEU A 1 67 ? 76.493 7.949 -25.746 1.00 12.86 ? 67 LEU A CD2 1 ATOM 506 N N . THR A 1 68 ? 71.395 9.649 -24.632 1.00 11.34 ? 68 THR A N 1 ATOM 507 C CA . THR A 1 68 ? 70.369 10.030 -23.662 1.00 11.23 ? 68 THR A CA 1 ATOM 508 C C . THR A 1 68 ? 69.035 9.388 -24.011 1.00 11.20 ? 68 THR A C 1 ATOM 509 O O . THR A 1 68 ? 68.771 9.083 -25.179 1.00 11.59 ? 68 THR A O 1 ATOM 510 C CB . THR A 1 68 ? 70.158 11.554 -23.634 1.00 13.08 ? 68 THR A CB 1 ATOM 511 O OG1 . THR A 1 68 ? 69.645 11.982 -24.901 1.00 14.21 ? 68 THR A OG1 1 ATOM 512 C CG2 . THR A 1 68 ? 71.470 12.276 -23.349 1.00 13.55 ? 68 THR A CG2 1 ATOM 513 N N . ALA A 1 69 ? 68.195 9.191 -23.000 1.00 10.29 ? 69 ALA A N 1 ATOM 514 C CA . ALA A 1 69 ? 66.887 8.605 -23.227 1.00 12.21 ? 69 ALA A CA 1 ATOM 515 C C . ALA A 1 69 ? 66.030 9.510 -24.101 1.00 12.53 ? 69 ALA A C 1 ATOM 516 O O . ALA A 1 69 ? 65.273 9.029 -24.936 1.00 13.00 ? 69 ALA A O 1 ATOM 517 C CB . ALA A 1 69 ? 66.184 8.339 -21.894 1.00 11.75 ? 69 ALA A CB 1 ATOM 518 N N . ASP A 1 70 ? 66.136 10.823 -23.930 1.00 14.74 ? 70 ASP A N 1 ATOM 519 C CA . ASP A 1 70 ? 65.312 11.700 -24.753 1.00 15.25 ? 70 ASP A CA 1 ATOM 520 C C . ASP A 1 70 ? 65.796 11.795 -26.193 1.00 15.37 ? 70 ASP A C 1 ATOM 521 O O . ASP A 1 70 ? 65.236 12.540 -26.996 1.00 16.53 ? 70 ASP A O 1 ATOM 522 C CB . ASP A 1 70 ? 65.201 13.103 -24.155 1.00 18.50 ? 70 ASP A CB 1 ATOM 523 C CG . ASP A 1 70 ? 66.539 13.701 -23.790 0.50 17.40 ? 70 ASP A CG 1 ATOM 524 O OD1 . ASP A 1 70 ? 67.504 13.552 -24.565 0.50 19.65 ? 70 ASP A OD1 1 ATOM 525 O OD2 . ASP A 1 70 ? 66.618 14.352 -22.727 0.50 20.10 ? 70 ASP A OD2 1 ATOM 526 N N . GLY A 1 71 ? 66.826 11.022 -26.523 1.00 13.84 ? 71 GLY A N 1 ATOM 527 C CA . GLY A 1 71 ? 67.340 11.007 -27.880 1.00 12.80 ? 71 GLY A CA 1 ATOM 528 C C . GLY A 1 71 ? 66.863 9.784 -28.648 1.00 11.03 ? 71 GLY A C 1 ATOM 529 O O . GLY A 1 71 ? 67.086 9.679 -29.849 1.00 11.04 ? 71 GLY A O 1 ATOM 530 N N . PHE A 1 72 ? 66.206 8.856 -27.956 1.00 12.14 ? 72 PHE A N 1 ATOM 531 C CA . PHE A 1 72 ? 65.714 7.621 -28.574 1.00 10.10 ? 72 PHE A CA 1 ATOM 532 C C . PHE A 1 72 ? 64.932 7.841 -29.872 1.00 10.30 ? 72 PHE A C 1 ATOM 533 O O . PHE A 1 72 ? 65.301 7.331 -30.934 1.00 10.52 ? 72 PHE A O 1 ATOM 534 C CB . PHE A 1 72 ? 64.841 6.841 -27.578 1.00 10.92 ? 72 PHE A CB 1 ATOM 535 C CG . PHE A 1 72 ? 64.201 5.620 -28.165 1.00 10.57 ? 72 PHE A CG 1 ATOM 536 C CD1 . PHE A 1 72 ? 64.983 4.581 -28.659 1.00 9.31 ? 72 PHE A CD1 1 ATOM 537 C CD2 . PHE A 1 72 ? 62.816 5.513 -28.239 1.00 9.71 ? 72 PHE A CD2 1 ATOM 538 C CE1 . PHE A 1 72 ? 64.397 3.458 -29.215 1.00 9.41 ? 72 PHE A CE1 1 ATOM 539 C CE2 . PHE A 1 72 ? 62.216 4.390 -28.794 1.00 10.64 ? 72 PHE A CE2 1 ATOM 540 C CZ . PHE A 1 72 ? 63.009 3.360 -29.284 1.00 10.34 ? 72 PHE A CZ 1 ATOM 541 N N . VAL A 1 73 ? 63.839 8.589 -29.786 1.00 10.25 ? 73 VAL A N 1 ATOM 542 C CA . VAL A 1 73 ? 63.024 8.866 -30.960 1.00 10.06 ? 73 VAL A CA 1 ATOM 543 C C . VAL A 1 73 ? 63.833 9.635 -32.002 1.00 10.55 ? 73 VAL A C 1 ATOM 544 O O . VAL A 1 73 ? 63.737 9.362 -33.196 1.00 10.24 ? 73 VAL A O 1 ATOM 545 C CB . VAL A 1 73 ? 61.762 9.674 -30.573 1.00 10.42 ? 73 VAL A CB 1 ATOM 546 C CG1 . VAL A 1 73 ? 61.036 10.151 -31.819 1.00 11.69 ? 73 VAL A CG1 1 ATOM 547 C CG2 . VAL A 1 73 ? 60.838 8.801 -29.734 1.00 12.94 ? 73 VAL A CG2 1 ATOM 548 N N . TYR A 1 74 ? 64.641 10.586 -31.543 1.00 10.80 ? 74 TYR A N 1 ATOM 549 C CA . TYR A 1 74 ? 65.464 11.389 -32.438 1.00 12.17 ? 74 TYR A CA 1 ATOM 550 C C . TYR A 1 74 ? 66.280 10.549 -33.420 1.00 11.06 ? 74 TYR A C 1 ATOM 551 O O . TYR A 1 74 ? 66.262 10.801 -34.622 1.00 11.19 ? 74 TYR A O 1 ATOM 552 C CB . TYR A 1 74 ? 66.422 12.268 -31.627 1.00 15.65 ? 74 TYR A CB 1 ATOM 553 C CG . TYR A 1 74 ? 67.315 13.148 -32.477 1.00 17.22 ? 74 TYR A CG 1 ATOM 554 C CD1 . TYR A 1 74 ? 66.908 14.426 -32.863 1.00 20.74 ? 74 TYR A CD1 1 ATOM 555 C CD2 . TYR A 1 74 ? 68.557 12.693 -32.919 1.00 19.79 ? 74 TYR A CD2 1 ATOM 556 C CE1 . TYR A 1 74 ? 67.717 15.229 -33.668 1.00 21.81 ? 74 TYR A CE1 1 ATOM 557 C CE2 . TYR A 1 74 ? 69.373 13.485 -33.726 1.00 21.98 ? 74 TYR A CE2 1 ATOM 558 C CZ . TYR A 1 74 ? 68.946 14.751 -34.095 1.00 23.01 ? 74 TYR A CZ 1 ATOM 559 O OH . TYR A 1 74 ? 69.751 15.533 -34.895 1.00 24.86 ? 74 TYR A OH 1 ATOM 560 N N . ASN A 1 75 ? 67.002 9.555 -32.910 1.00 10.28 ? 75 ASN A N 1 ATOM 561 C CA . ASN A 1 75 ? 67.834 8.721 -33.770 1.00 9.47 ? 75 ASN A CA 1 ATOM 562 C C . ASN A 1 75 ? 67.020 8.038 -34.865 1.00 9.88 ? 75 ASN A C 1 ATOM 563 O O . ASN A 1 75 ? 67.474 7.924 -36.005 1.00 10.63 ? 75 ASN A O 1 ATOM 564 C CB . ASN A 1 75 ? 68.569 7.676 -32.927 1.00 11.02 ? 75 ASN A CB 1 ATOM 565 C CG . ASN A 1 75 ? 69.364 8.299 -31.796 1.00 11.74 ? 75 ASN A CG 1 ATOM 566 O OD1 . ASN A 1 75 ? 69.385 7.781 -30.679 1.00 12.97 ? 75 ASN A OD1 1 ATOM 567 N ND2 . ASN A 1 75 ? 70.025 9.417 -32.081 1.00 9.56 ? 75 ASN A ND2 1 ATOM 568 N N . LEU A 1 76 ? 65.814 7.593 -34.520 1.00 9.45 ? 76 LEU A N 1 ATOM 569 C CA . LEU A 1 76 ? 64.944 6.922 -35.482 1.00 9.67 ? 76 LEU A CA 1 ATOM 570 C C . LEU A 1 76 ? 64.406 7.898 -36.531 1.00 10.12 ? 76 LEU A C 1 ATOM 571 O O . LEU A 1 76 ? 64.128 7.512 -37.665 1.00 9.49 ? 76 LEU A O 1 ATOM 572 C CB . LEU A 1 76 ? 63.770 6.250 -34.758 1.00 9.52 ? 76 LEU A CB 1 ATOM 573 C CG . LEU A 1 76 ? 64.112 5.188 -33.709 1.00 10.10 ? 76 LEU A CG 1 ATOM 574 C CD1 . LEU A 1 76 ? 62.831 4.667 -33.069 1.00 11.09 ? 76 LEU A CD1 1 ATOM 575 C CD2 . LEU A 1 76 ? 64.878 4.049 -34.364 1.00 12.13 ? 76 LEU A CD2 1 ATOM 576 N N . GLN A 1 77 ? 64.272 9.165 -36.149 1.00 10.41 ? 77 GLN A N 1 ATOM 577 C CA . GLN A 1 77 ? 63.760 10.190 -37.055 1.00 11.49 ? 77 GLN A CA 1 ATOM 578 C C . GLN A 1 77 ? 64.794 10.702 -38.048 1.00 12.40 ? 77 GLN A C 1 ATOM 579 O O . GLN A 1 77 ? 64.438 11.206 -39.111 1.00 13.06 ? 77 GLN A O 1 ATOM 580 C CB . GLN A 1 77 ? 63.244 11.393 -36.265 1.00 11.00 ? 77 GLN A CB 1 ATOM 581 C CG . GLN A 1 77 ? 62.056 11.132 -35.366 1.00 12.92 ? 77 GLN A CG 1 ATOM 582 C CD . GLN A 1 77 ? 61.760 12.329 -34.491 1.00 12.44 ? 77 GLN A CD 1 ATOM 583 O OE1 . GLN A 1 77 ? 62.644 12.827 -33.797 1.00 12.08 ? 77 GLN A OE1 1 ATOM 584 N NE2 . GLN A 1 77 ? 60.519 12.801 -34.518 1.00 13.26 ? 77 GLN A NE2 1 ATOM 585 N N . GLN A 1 78 ? 66.072 10.580 -37.703 1.00 12.89 ? 78 GLN A N 1 ATOM 586 C CA . GLN A 1 78 ? 67.130 11.081 -38.567 1.00 12.90 ? 78 GLN A CA 1 ATOM 587 C C . GLN A 1 78 ? 67.262 10.379 -39.908 1.00 13.11 ? 78 GLN A C 1 ATOM 588 O O . GLN A 1 78 ? 67.185 9.155 -40.006 1.00 12.54 ? 78 GLN A O 1 ATOM 589 C CB . GLN A 1 78 ? 68.466 11.065 -37.821 1.00 13.44 ? 78 GLN A CB 1 ATOM 590 C CG A GLN A 1 78 ? 68.431 11.913 -36.559 0.50 12.67 ? 78 GLN A CG 1 ATOM 591 C CG B GLN A 1 78 ? 69.701 11.154 -38.723 0.50 12.69 ? 78 GLN A CG 1 ATOM 592 C CD A GLN A 1 78 ? 67.704 13.237 -36.767 0.50 13.31 ? 78 GLN A CD 1 ATOM 593 C CD B GLN A 1 78 ? 70.980 11.408 -37.951 0.50 13.33 ? 78 GLN A CD 1 ATOM 594 O OE1 A GLN A 1 78 ? 68.186 14.124 -37.476 0.50 13.46 ? 78 GLN A OE1 1 ATOM 595 O OE1 B GLN A 1 78 ? 71.332 10.648 -37.048 0.50 13.50 ? 78 GLN A OE1 1 ATOM 596 N NE2 A GLN A 1 78 ? 66.531 13.368 -36.156 0.50 8.69 ? 78 GLN A NE2 1 ATOM 597 N NE2 B GLN A 1 78 ? 71.827 12.414 -38.137 0.50 8.86 ? 78 GLN A NE2 1 ATOM 598 N N . GLU A 1 79 ? 67.455 11.176 -40.951 1.00 14.15 ? 79 GLU A N 1 ATOM 599 C CA . GLU A 1 79 ? 67.593 10.645 -42.294 1.00 15.73 ? 79 GLU A CA 1 ATOM 600 C C . GLU A 1 79 ? 68.831 9.757 -42.379 1.00 14.31 ? 79 GLU A C 1 ATOM 601 O O . GLU A 1 79 ? 69.881 10.066 -41.812 1.00 13.61 ? 79 GLU A O 1 ATOM 602 C CB . GLU A 1 79 ? 67.677 11.799 -43.295 1.00 20.40 ? 79 GLU A CB 1 ATOM 603 C CG . GLU A 1 79 ? 66.586 12.841 -43.074 1.00 28.00 ? 79 GLU A CG 1 ATOM 604 C CD . GLU A 1 79 ? 66.653 13.999 -44.053 1.00 32.01 ? 79 GLU A CD 1 ATOM 605 O OE1 . GLU A 1 79 ? 67.774 14.468 -44.347 1.00 34.58 ? 79 GLU A OE1 1 ATOM 606 O OE2 . GLU A 1 79 ? 65.581 14.449 -44.514 1.00 35.34 ? 79 GLU A OE2 1 ATOM 607 N N . ASP A 1 80 ? 68.686 8.643 -43.084 1.00 13.89 ? 80 ASP A N 1 ATOM 608 C CA . ASP A 1 80 ? 69.762 7.676 -43.253 1.00 12.60 ? 80 ASP A CA 1 ATOM 609 C C . ASP A 1 80 ? 70.694 8.120 -44.375 1.00 13.19 ? 80 ASP A C 1 ATOM 610 O O . ASP A 1 80 ? 70.355 7.991 -45.552 1.00 13.90 ? 80 ASP A O 1 ATOM 611 C CB . ASP A 1 80 ? 69.160 6.309 -43.591 1.00 12.37 ? 80 ASP A CB 1 ATOM 612 C CG . ASP A 1 80 ? 70.191 5.203 -43.626 1.00 12.24 ? 80 ASP A CG 1 ATOM 613 O OD1 . ASP A 1 80 ? 71.401 5.503 -43.715 1.00 13.34 ? 80 ASP A OD1 1 ATOM 614 O OD2 . ASP A 1 80 ? 69.783 4.022 -43.577 1.00 13.33 ? 80 ASP A OD2 1 ATOM 615 N N . ASP A 1 81 ? 71.862 8.646 -44.013 1.00 12.05 ? 81 ASP A N 1 ATOM 616 C CA . ASP A 1 81 ? 72.823 9.096 -45.015 1.00 12.84 ? 81 ASP A CA 1 ATOM 617 C C . ASP A 1 81 ? 73.916 8.059 -45.246 1.00 12.10 ? 81 ASP A C 1 ATOM 618 O O . ASP A 1 81 ? 74.925 8.340 -45.894 1.00 12.59 ? 81 ASP A O 1 ATOM 619 C CB . ASP A 1 81 ? 73.454 10.433 -44.602 1.00 12.68 ? 81 ASP A CB 1 ATOM 620 C CG . ASP A 1 81 ? 74.279 10.333 -43.331 1.00 15.31 ? 81 ASP A CG 1 ATOM 621 O OD1 . ASP A 1 81 ? 74.469 9.212 -42.817 1.00 14.18 ? 81 ASP A OD1 1 ATOM 622 O OD2 . ASP A 1 81 ? 74.745 11.386 -42.844 1.00 16.24 ? 81 ASP A OD2 1 ATOM 623 N N . GLY A 1 82 ? 73.705 6.858 -44.715 1.00 12.34 ? 82 GLY A N 1 ATOM 624 C CA . GLY A 1 82 ? 74.682 5.797 -44.875 1.00 11.23 ? 82 GLY A CA 1 ATOM 625 C C . GLY A 1 82 ? 75.744 5.771 -43.791 1.00 11.38 ? 82 GLY A C 1 ATOM 626 O O . GLY A 1 82 ? 76.539 4.832 -43.721 1.00 11.62 ? 82 GLY A O 1 ATOM 627 N N . LYS A 1 83 ? 75.761 6.793 -42.941 1.00 12.01 ? 83 LYS A N 1 ATOM 628 C CA . LYS A 1 83 ? 76.750 6.872 -41.871 1.00 12.69 ? 83 LYS A CA 1 ATOM 629 C C . LYS A 1 83 ? 76.107 6.969 -40.495 1.00 10.70 ? 83 LYS A C 1 ATOM 630 O O . LYS A 1 83 ? 76.743 6.676 -39.482 1.00 11.10 ? 83 LYS A O 1 ATOM 631 C CB . LYS A 1 83 ? 77.662 8.082 -42.094 1.00 15.44 ? 83 LYS A CB 1 ATOM 632 C CG . LYS A 1 83 ? 78.273 8.139 -43.487 1.00 22.22 ? 83 LYS A CG 1 ATOM 633 C CD . LYS A 1 83 ? 79.159 9.363 -43.667 1.00 26.26 ? 83 LYS A CD 1 ATOM 634 C CE . LYS A 1 83 ? 79.705 9.439 -45.088 1.00 30.19 ? 83 LYS A CE 1 ATOM 635 N NZ . LYS A 1 83 ? 80.562 10.639 -45.304 1.00 32.70 ? 83 LYS A NZ 1 ATOM 636 N N . THR A 1 84 ? 74.846 7.386 -40.463 1.00 10.19 ? 84 THR A N 1 ATOM 637 C CA . THR A 1 84 ? 74.114 7.536 -39.210 1.00 9.55 ? 84 THR A CA 1 ATOM 638 C C . THR A 1 84 ? 74.007 6.220 -38.435 1.00 9.32 ? 84 THR A C 1 ATOM 639 O O . THR A 1 84 ? 74.063 5.136 -39.018 1.00 9.56 ? 84 THR A O 1 ATOM 640 C CB . THR A 1 84 ? 72.711 8.106 -39.476 1.00 10.74 ? 84 THR A CB 1 ATOM 641 O OG1 . THR A 1 84 ? 72.107 7.397 -40.562 1.00 10.17 ? 84 THR A OG1 1 ATOM 642 C CG2 . THR A 1 84 ? 72.804 9.587 -39.834 1.00 11.55 ? 84 THR A CG2 1 ATOM 643 N N . PRO A 1 85 ? 73.847 6.301 -37.103 1.00 9.46 ? 85 PRO A N 1 ATOM 644 C CA . PRO A 1 85 ? 73.743 5.113 -36.247 1.00 8.69 ? 85 PRO A CA 1 ATOM 645 C C . PRO A 1 85 ? 72.520 4.227 -36.453 1.00 8.86 ? 85 PRO A C 1 ATOM 646 O O . PRO A 1 85 ? 72.508 3.069 -36.028 1.00 8.62 ? 85 PRO A O 1 ATOM 647 C CB . PRO A 1 85 ? 73.819 5.695 -34.836 1.00 8.26 ? 85 PRO A CB 1 ATOM 648 C CG . PRO A 1 85 ? 73.205 7.063 -34.999 1.00 8.62 ? 85 PRO A CG 1 ATOM 649 C CD . PRO A 1 85 ? 73.815 7.536 -36.294 1.00 8.20 ? 85 PRO A CD 1 ATOM 650 N N . VAL A 1 86 ? 71.492 4.772 -37.093 1.00 7.86 ? 86 VAL A N 1 ATOM 651 C CA . VAL A 1 86 ? 70.281 4.012 -37.364 1.00 8.14 ? 86 VAL A CA 1 ATOM 652 C C . VAL A 1 86 ? 70.178 3.726 -38.858 1.00 8.64 ? 86 VAL A C 1 ATOM 653 O O . VAL A 1 86 ? 69.962 4.641 -39.660 1.00 10.69 ? 86 VAL A O 1 ATOM 654 C CB . VAL A 1 86 ? 69.016 4.778 -36.914 1.00 8.79 ? 86 VAL A CB 1 ATOM 655 C CG1 . VAL A 1 86 ? 67.768 3.981 -37.279 1.00 10.16 ? 86 VAL A CG1 1 ATOM 656 C CG2 . VAL A 1 86 ? 69.064 5.023 -35.408 1.00 10.12 ? 86 VAL A CG2 1 ATOM 657 N N . GLU A 1 87 ? 70.354 2.460 -39.233 1.00 7.31 ? 87 GLU A N 1 ATOM 658 C CA . GLU A 1 87 ? 70.255 2.075 -40.634 1.00 6.80 ? 87 GLU A CA 1 ATOM 659 C C . GLU A 1 87 ? 68.842 1.589 -40.913 1.00 8.09 ? 87 GLU A C 1 ATOM 660 O O . GLU A 1 87 ? 68.335 0.686 -40.241 1.00 9.30 ? 87 GLU A O 1 ATOM 661 C CB . GLU A 1 87 ? 71.250 0.964 -40.993 1.00 8.85 ? 87 GLU A CB 1 ATOM 662 C CG . GLU A 1 87 ? 71.044 0.462 -42.423 1.00 8.78 ? 87 GLU A CG 1 ATOM 663 C CD . GLU A 1 87 ? 72.090 -0.535 -42.892 1.00 10.47 ? 87 GLU A CD 1 ATOM 664 O OE1 . GLU A 1 87 ? 72.956 -0.937 -42.088 1.00 10.35 ? 87 GLU A OE1 1 ATOM 665 O OE2 . GLU A 1 87 ? 72.042 -0.916 -44.082 1.00 13.21 ? 87 GLU A OE2 1 ATOM 666 N N . ARG A 1 88 ? 68.210 2.193 -41.910 1.00 6.92 ? 88 ARG A N 1 ATOM 667 C CA . ARG A 1 88 ? 66.849 1.835 -42.279 1.00 7.79 ? 88 ARG A CA 1 ATOM 668 C C . ARG A 1 88 ? 66.793 0.712 -43.301 1.00 7.94 ? 88 ARG A C 1 ATOM 669 O O . ARG A 1 88 ? 67.674 0.589 -44.151 1.00 10.20 ? 88 ARG A O 1 ATOM 670 C CB . ARG A 1 88 ? 66.131 3.049 -42.873 1.00 9.02 ? 88 ARG A CB 1 ATOM 671 C CG . ARG A 1 88 ? 66.061 4.256 -41.966 1.00 8.04 ? 88 ARG A CG 1 ATOM 672 C CD . ARG A 1 88 ? 65.304 5.395 -42.647 1.00 10.58 ? 88 ARG A CD 1 ATOM 673 N NE . ARG A 1 88 ? 65.137 6.542 -41.763 1.00 12.74 ? 88 ARG A NE 1 ATOM 674 C CZ . ARG A 1 88 ? 64.363 7.589 -42.036 1.00 13.24 ? 88 ARG A CZ 1 ATOM 675 N NH1 . ARG A 1 88 ? 63.683 7.635 -43.174 1.00 13.16 ? 88 ARG A NH1 1 ATOM 676 N NH2 . ARG A 1 88 ? 64.264 8.586 -41.167 1.00 14.55 ? 88 ARG A NH2 1 ATOM 677 N N . PHE A 1 89 ? 65.755 -0.112 -43.201 1.00 8.62 ? 89 PHE A N 1 ATOM 678 C CA . PHE A 1 89 ? 65.526 -1.174 -44.171 1.00 8.80 ? 89 PHE A CA 1 ATOM 679 C C . PHE A 1 89 ? 64.065 -1.582 -44.128 1.00 7.83 ? 89 PHE A C 1 ATOM 680 O O . PHE A 1 89 ? 63.349 -1.263 -43.179 1.00 8.30 ? 89 PHE A O 1 ATOM 681 C CB . PHE A 1 89 ? 66.482 -2.370 -43.961 1.00 9.63 ? 89 PHE A CB 1 ATOM 682 C CG . PHE A 1 89 ? 66.191 -3.227 -42.755 1.00 9.94 ? 89 PHE A CG 1 ATOM 683 C CD1 . PHE A 1 89 ? 65.374 -4.351 -42.861 1.00 9.07 ? 89 PHE A CD1 1 ATOM 684 C CD2 . PHE A 1 89 ? 66.807 -2.963 -41.536 1.00 9.90 ? 89 PHE A CD2 1 ATOM 685 C CE1 . PHE A 1 89 ? 65.185 -5.202 -41.774 1.00 8.92 ? 89 PHE A CE1 1 ATOM 686 C CE2 . PHE A 1 89 ? 66.622 -3.806 -40.444 1.00 9.65 ? 89 PHE A CE2 1 ATOM 687 C CZ . PHE A 1 89 ? 65.812 -4.928 -40.563 1.00 9.53 ? 89 PHE A CZ 1 ATOM 688 N N . VAL A 1 90 ? 63.605 -2.234 -45.186 1.00 7.53 ? 90 VAL A N 1 ATOM 689 C CA . VAL A 1 90 ? 62.218 -2.663 -45.258 1.00 7.65 ? 90 VAL A CA 1 ATOM 690 C C . VAL A 1 90 ? 62.227 -4.135 -45.624 1.00 8.58 ? 90 VAL A C 1 ATOM 691 O O . VAL A 1 90 ? 62.879 -4.523 -46.596 1.00 8.63 ? 90 VAL A O 1 ATOM 692 C CB . VAL A 1 90 ? 61.446 -1.889 -46.350 1.00 8.71 ? 90 VAL A CB 1 ATOM 693 C CG1 . VAL A 1 90 ? 59.965 -2.223 -46.276 1.00 10.00 ? 90 VAL A CG1 1 ATOM 694 C CG2 . VAL A 1 90 ? 61.660 -0.396 -46.185 1.00 10.00 ? 90 VAL A CG2 1 ATOM 695 N N . SER A 1 91 ? 61.519 -4.957 -44.853 1.00 6.89 ? 91 SER A N 1 ATOM 696 C CA . SER A 1 91 ? 61.484 -6.381 -45.160 1.00 7.65 ? 91 SER A CA 1 ATOM 697 C C . SER A 1 91 ? 60.667 -6.583 -46.433 1.00 7.57 ? 91 SER A C 1 ATOM 698 O O . SER A 1 91 ? 59.931 -5.687 -46.862 1.00 7.25 ? 91 SER A O 1 ATOM 699 C CB . SER A 1 91 ? 60.860 -7.182 -44.011 1.00 7.54 ? 91 SER A CB 1 ATOM 700 O OG . SER A 1 91 ? 59.453 -7.015 -43.944 1.00 9.05 ? 91 SER A OG 1 ATOM 701 N N . GLU A 1 92 ? 60.811 -7.756 -47.040 1.00 6.59 ? 92 GLU A N 1 ATOM 702 C CA . GLU A 1 92 ? 60.086 -8.078 -48.262 1.00 7.50 ? 92 GLU A CA 1 ATOM 703 C C . GLU A 1 92 ? 58.590 -8.135 -47.955 1.00 8.61 ? 92 GLU A C 1 ATOM 704 O O . GLU A 1 92 ? 57.760 -8.097 -48.867 1.00 10.13 ? 92 GLU A O 1 ATOM 705 C CB . GLU A 1 92 ? 60.569 -9.424 -48.818 1.00 8.12 ? 92 GLU A CB 1 ATOM 706 C CG A GLU A 1 92 ? 60.097 -9.734 -50.232 0.50 10.25 ? 92 GLU A CG 1 ATOM 707 C CG B GLU A 1 92 ? 61.975 -9.347 -49.394 0.50 10.41 ? 92 GLU A CG 1 ATOM 708 C CD A GLU A 1 92 ? 60.593 -11.084 -50.722 0.50 12.51 ? 92 GLU A CD 1 ATOM 709 C CD B GLU A 1 92 ? 62.398 -10.653 -50.036 0.50 13.25 ? 92 GLU A CD 1 ATOM 710 O OE1 A GLU A 1 92 ? 61.713 -11.480 -50.335 0.50 12.72 ? 92 GLU A OE1 1 ATOM 711 O OE1 B GLU A 1 92 ? 61.571 -11.588 -50.080 0.50 12.84 ? 92 GLU A OE1 1 ATOM 712 O OE2 A GLU A 1 92 ? 59.869 -11.741 -51.502 0.50 13.35 ? 92 GLU A OE2 1 ATOM 713 O OE2 B GLU A 1 92 ? 63.556 -10.743 -50.495 0.50 13.25 ? 92 GLU A OE2 1 ATOM 714 N N . ASP A 1 93 ? 58.253 -8.215 -46.666 1.00 8.33 ? 93 ASP A N 1 ATOM 715 C CA . ASP A 1 93 ? 56.856 -8.260 -46.232 1.00 7.38 ? 93 ASP A CA 1 ATOM 716 C C . ASP A 1 93 ? 56.242 -6.866 -46.337 1.00 7.66 ? 93 ASP A C 1 ATOM 717 O O . ASP A 1 93 ? 55.018 -6.717 -46.311 1.00 9.04 ? 93 ASP A O 1 ATOM 718 C CB . ASP A 1 93 ? 56.734 -8.718 -44.773 1.00 7.69 ? 93 ASP A CB 1 ATOM 719 C CG . ASP A 1 93 ? 57.602 -9.914 -44.451 1.00 8.87 ? 93 ASP A CG 1 ATOM 720 O OD1 . ASP A 1 93 ? 58.777 -9.709 -44.077 1.00 8.61 ? 93 ASP A OD1 1 ATOM 721 O OD2 . ASP A 1 93 ? 57.108 -11.057 -44.570 1.00 10.07 ? 93 ASP A OD2 1 ATOM 722 N N . GLY A 1 94 ? 57.104 -5.855 -46.435 1.00 8.92 ? 94 GLY A N 1 ATOM 723 C CA . GLY A 1 94 ? 56.655 -4.475 -46.531 1.00 8.59 ? 94 GLY A CA 1 ATOM 724 C C . GLY A 1 94 ? 56.668 -3.742 -45.198 1.00 9.80 ? 94 GLY A C 1 ATOM 725 O O . GLY A 1 94 ? 56.073 -2.673 -45.070 1.00 12.14 ? 94 GLY A O 1 ATOM 726 N N . ILE A 1 95 ? 57.367 -4.303 -44.214 1.00 8.28 ? 95 ILE A N 1 ATOM 727 C CA . ILE A 1 95 ? 57.434 -3.718 -42.875 1.00 7.94 ? 95 ILE A CA 1 ATOM 728 C C . ILE A 1 95 ? 58.739 -2.960 -42.619 1.00 8.06 ? 95 ILE A C 1 ATOM 729 O O . ILE A 1 95 ? 59.828 -3.530 -42.701 1.00 7.84 ? 95 ILE A O 1 ATOM 730 C CB . ILE A 1 95 ? 57.259 -4.821 -41.802 1.00 6.92 ? 95 ILE A CB 1 ATOM 731 C CG1 . ILE A 1 95 ? 55.929 -5.550 -42.023 1.00 7.08 ? 95 ILE A CG1 1 ATOM 732 C CG2 . ILE A 1 95 ? 57.301 -4.221 -40.400 1.00 6.59 ? 95 ILE A CG2 1 ATOM 733 C CD1 . ILE A 1 95 ? 54.698 -4.649 -41.946 1.00 9.74 ? 95 ILE A CD1 1 ATOM 734 N N . ASP A 1 96 ? 58.617 -1.669 -42.318 1.00 7.95 ? 96 ASP A N 1 ATOM 735 C CA . ASP A 1 96 ? 59.777 -0.825 -42.044 1.00 6.95 ? 96 ASP A CA 1 ATOM 736 C C . ASP A 1 96 ? 60.516 -1.338 -40.812 1.00 8.42 ? 96 ASP A C 1 ATOM 737 O O . ASP A 1 96 ? 59.903 -1.851 -39.868 1.00 7.73 ? 96 ASP A O 1 ATOM 738 C CB . ASP A 1 96 ? 59.353 0.630 -41.819 1.00 7.94 ? 96 ASP A CB 1 ATOM 739 C CG . ASP A 1 96 ? 58.847 1.301 -43.085 1.00 11.72 ? 96 ASP A CG 1 ATOM 740 O OD1 . ASP A 1 96 ? 59.043 0.741 -44.188 1.00 12.33 ? 96 ASP A OD1 1 ATOM 741 O OD2 . ASP A 1 96 ? 58.262 2.404 -42.973 1.00 11.88 ? 96 ASP A OD2 1 ATOM 742 N N . ASN A 1 97 ? 61.833 -1.182 -40.817 1.00 7.17 ? 97 ASN A N 1 ATOM 743 C CA . ASN A 1 97 ? 62.652 -1.670 -39.716 1.00 7.33 ? 97 ASN A CA 1 ATOM 744 C C . ASN A 1 97 ? 63.984 -0.922 -39.668 1.00 8.32 ? 97 ASN A C 1 ATOM 745 O O . ASN A 1 97 ? 64.297 -0.126 -40.562 1.00 8.34 ? 97 ASN A O 1 ATOM 746 C CB . ASN A 1 97 ? 62.910 -3.168 -39.917 1.00 6.75 ? 97 ASN A CB 1 ATOM 747 C CG . ASN A 1 97 ? 62.927 -3.941 -38.615 1.00 7.25 ? 97 ASN A CG 1 ATOM 748 O OD1 . ASN A 1 97 ? 63.406 -3.451 -37.599 1.00 7.95 ? 97 ASN A OD1 1 ATOM 749 N ND2 . ASN A 1 97 ? 62.415 -5.171 -38.648 1.00 8.23 ? 97 ASN A ND2 1 ATOM 750 N N . VAL A 1 98 ? 64.764 -1.175 -38.620 1.00 7.15 ? 98 VAL A N 1 ATOM 751 C CA . VAL A 1 98 ? 66.069 -0.544 -38.462 1.00 7.85 ? 98 VAL A CA 1 ATOM 752 C C . VAL A 1 98 ? 67.055 -1.455 -37.734 1.00 7.33 ? 98 VAL A C 1 ATOM 753 O O . VAL A 1 98 ? 66.660 -2.402 -37.056 1.00 8.24 ? 98 VAL A O 1 ATOM 754 C CB . VAL A 1 98 ? 65.993 0.783 -37.648 1.00 8.30 ? 98 VAL A CB 1 ATOM 755 C CG1 . VAL A 1 98 ? 65.014 1.746 -38.293 1.00 7.64 ? 98 VAL A CG1 1 ATOM 756 C CG2 . VAL A 1 98 ? 65.591 0.496 -36.200 1.00 9.20 ? 98 VAL A CG2 1 ATOM 757 N N . ARG A 1 99 ? 68.341 -1.170 -37.910 1.00 8.19 ? 99 ARG A N 1 ATOM 758 C CA . ARG A 1 99 ? 69.403 -1.901 -37.228 1.00 6.97 ? 99 ARG A CA 1 ATOM 759 C C . ARG A 1 99 ? 70.511 -0.908 -36.911 1.00 7.42 ? 99 ARG A C 1 ATOM 760 O O . ARG A 1 99 ? 70.634 0.126 -37.569 1.00 7.70 ? 99 ARG A O 1 ATOM 761 C CB . ARG A 1 99 ? 69.950 -3.062 -38.071 1.00 7.96 ? 99 ARG A CB 1 ATOM 762 C CG . ARG A 1 99 ? 70.618 -2.687 -39.379 1.00 6.82 ? 99 ARG A CG 1 ATOM 763 C CD . ARG A 1 99 ? 71.411 -3.883 -39.907 1.00 7.39 ? 99 ARG A CD 1 ATOM 764 N NE . ARG A 1 99 ? 71.705 -3.749 -41.325 1.00 8.55 ? 99 ARG A NE 1 ATOM 765 C CZ . ARG A 1 99 ? 72.770 -4.265 -41.930 1.00 7.79 ? 99 ARG A CZ 1 ATOM 766 N NH1 . ARG A 1 99 ? 73.669 -4.962 -41.243 1.00 7.65 ? 99 ARG A NH1 1 ATOM 767 N NH2 . ARG A 1 99 ? 72.937 -4.070 -43.230 1.00 9.36 ? 99 ARG A NH2 1 ATOM 768 N N . GLY A 1 100 ? 71.303 -1.214 -35.892 1.00 7.23 ? 100 GLY A N 1 ATOM 769 C CA . GLY A 1 100 ? 72.378 -0.320 -35.510 1.00 6.93 ? 100 GLY A CA 1 ATOM 770 C C . GLY A 1 100 ? 73.572 -0.318 -36.445 1.00 7.94 ? 100 GLY A C 1 ATOM 771 O O . GLY A 1 100 ? 73.861 -1.306 -37.116 1.00 6.38 ? 100 GLY A O 1 ATOM 772 N N . ARG A 1 101 ? 74.271 0.810 -36.474 1.00 6.49 ? 101 ARG A N 1 ATOM 773 C CA . ARG A 1 101 ? 75.460 0.988 -37.306 1.00 6.96 ? 101 ARG A CA 1 ATOM 774 C C . ARG A 1 101 ? 76.314 1.994 -36.541 1.00 8.01 ? 101 ARG A C 1 ATOM 775 O O . ARG A 1 101 ? 76.401 3.165 -36.905 1.00 8.29 ? 101 ARG A O 1 ATOM 776 C CB . ARG A 1 101 ? 75.058 1.543 -38.676 1.00 8.25 ? 101 ARG A CB 1 ATOM 777 C CG . ARG A 1 101 ? 76.213 1.711 -39.656 1.00 8.46 ? 101 ARG A CG 1 ATOM 778 C CD . ARG A 1 101 ? 75.690 2.029 -41.040 1.00 10.57 ? 101 ARG A CD 1 ATOM 779 N NE . ARG A 1 101 ? 74.816 3.195 -41.008 1.00 11.68 ? 101 ARG A NE 1 ATOM 780 C CZ . ARG A 1 101 ? 73.964 3.523 -41.972 1.00 11.56 ? 101 ARG A CZ 1 ATOM 781 N NH1 . ARG A 1 101 ? 73.863 2.773 -43.063 1.00 12.23 ? 101 ARG A NH1 1 ATOM 782 N NH2 . ARG A 1 101 ? 73.202 4.596 -41.836 1.00 11.72 ? 101 ARG A NH2 1 ATOM 783 N N . VAL A 1 102 ? 76.934 1.516 -35.466 1.00 8.13 ? 102 VAL A N 1 ATOM 784 C CA . VAL A 1 102 ? 77.728 2.363 -34.587 1.00 9.04 ? 102 VAL A CA 1 ATOM 785 C C . VAL A 1 102 ? 78.421 1.453 -33.570 1.00 9.59 ? 102 VAL A C 1 ATOM 786 O O . VAL A 1 102 ? 77.982 0.324 -33.352 1.00 8.26 ? 102 VAL A O 1 ATOM 787 C CB . VAL A 1 102 ? 76.781 3.355 -33.850 1.00 9.33 ? 102 VAL A CB 1 ATOM 788 C CG1 . VAL A 1 102 ? 75.700 2.575 -33.112 1.00 9.30 ? 102 VAL A CG1 1 ATOM 789 C CG2 . VAL A 1 102 ? 77.559 4.243 -32.889 1.00 8.94 ? 102 VAL A CG2 1 ATOM 790 N N . LEU A 1 103 ? 79.507 1.923 -32.963 1.00 8.89 ? 103 LEU A N 1 ATOM 791 C CA . LEU A 1 103 ? 80.194 1.115 -31.961 1.00 8.79 ? 103 LEU A CA 1 ATOM 792 C C . LEU A 1 103 ? 79.237 0.962 -30.782 1.00 8.80 ? 103 LEU A C 1 ATOM 793 O O . LEU A 1 103 ? 78.703 1.947 -30.272 1.00 8.83 ? 103 LEU A O 1 ATOM 794 C CB . LEU A 1 103 ? 81.491 1.790 -31.510 1.00 8.75 ? 103 LEU A CB 1 ATOM 795 C CG . LEU A 1 103 ? 82.345 0.968 -30.539 1.00 8.64 ? 103 LEU A CG 1 ATOM 796 C CD1 . LEU A 1 103 ? 82.759 -0.342 -31.205 1.00 8.31 ? 103 LEU A CD1 1 ATOM 797 C CD2 . LEU A 1 103 ? 83.573 1.765 -30.123 1.00 8.55 ? 103 LEU A CD2 1 ATOM 798 N N . GLY A 1 104 ? 79.032 -0.278 -30.353 1.00 6.63 ? 104 GLY A N 1 ATOM 799 C CA . GLY A 1 104 ? 78.102 -0.557 -29.277 1.00 7.67 ? 104 GLY A CA 1 ATOM 800 C C . GLY A 1 104 ? 76.922 -1.268 -29.920 1.00 6.56 ? 104 GLY A C 1 ATOM 801 O O . GLY A 1 104 ? 76.080 -1.869 -29.250 1.00 8.82 ? 104 GLY A O 1 ATOM 802 N N . GLY A 1 105 ? 76.863 -1.188 -31.245 1.00 6.60 ? 105 GLY A N 1 ATOM 803 C CA . GLY A 1 105 ? 75.798 -1.842 -31.978 1.00 7.06 ? 105 GLY A CA 1 ATOM 804 C C . GLY A 1 105 ? 74.409 -1.305 -31.708 1.00 7.14 ? 105 GLY A C 1 ATOM 805 O O . GLY A 1 105 ? 74.223 -0.128 -31.389 1.00 6.97 ? 105 GLY A O 1 ATOM 806 N N . THR A 1 106 ? 73.421 -2.180 -31.834 1.00 6.31 ? 106 THR A N 1 ATOM 807 C CA . THR A 1 106 ? 72.043 -1.786 -31.631 1.00 5.63 ? 106 THR A CA 1 ATOM 808 C C . THR A 1 106 ? 71.716 -1.462 -30.173 1.00 6.95 ? 106 THR A C 1 ATOM 809 O O . THR A 1 106 ? 70.681 -0.856 -29.887 1.00 5.68 ? 106 THR A O 1 ATOM 810 C CB . THR A 1 106 ? 71.105 -2.876 -32.214 1.00 5.60 ? 106 THR A CB 1 ATOM 811 O OG1 . THR A 1 106 ? 71.413 -3.046 -33.606 1.00 6.42 ? 106 THR A OG1 1 ATOM 812 C CG2 . THR A 1 106 ? 69.650 -2.478 -32.085 1.00 6.82 ? 106 THR A CG2 1 ATOM 813 N N . SER A 1 107 ? 72.599 -1.838 -29.248 1.00 6.77 ? 107 SER A N 1 ATOM 814 C CA . SER A 1 107 ? 72.355 -1.526 -27.839 1.00 7.71 ? 107 SER A CA 1 ATOM 815 C C . SER A 1 107 ? 72.511 -0.014 -27.647 1.00 8.58 ? 107 SER A C 1 ATOM 816 O O . SER A 1 107 ? 72.106 0.536 -26.623 1.00 8.98 ? 107 SER A O 1 ATOM 817 C CB . SER A 1 107 ? 73.336 -2.271 -26.921 1.00 8.16 ? 107 SER A CB 1 ATOM 818 O OG . SER A 1 107 ? 74.638 -1.715 -26.971 1.00 8.77 ? 107 SER A OG 1 ATOM 819 N N . ILE A 1 108 ? 73.089 0.646 -28.649 1.00 10.08 ? 108 ILE A N 1 ATOM 820 C CA . ILE A 1 108 ? 73.312 2.095 -28.620 1.00 11.20 ? 108 ILE A CA 1 ATOM 821 C C . ILE A 1 108 ? 72.091 2.897 -29.089 1.00 11.23 ? 108 ILE A C 1 ATOM 822 O O . ILE A 1 108 ? 71.993 4.102 -28.834 1.00 10.95 ? 108 ILE A O 1 ATOM 823 C CB . ILE A 1 108 ? 74.547 2.473 -29.505 1.00 14.15 ? 108 ILE A CB 1 ATOM 824 C CG1 . ILE A 1 108 ? 75.845 2.095 -28.786 1.00 17.45 ? 108 ILE A CG1 1 ATOM 825 C CG2 . ILE A 1 108 ? 74.551 3.963 -29.828 1.00 16.10 ? 108 ILE A CG2 1 ATOM 826 C CD1 . ILE A 1 108 ? 76.159 2.960 -27.569 1.00 20.61 ? 108 ILE A CD1 1 ATOM 827 N N . ILE A 1 109 ? 71.152 2.235 -29.760 1.00 10.31 ? 109 ILE A N 1 ATOM 828 C CA . ILE A 1 109 ? 69.966 2.926 -30.266 1.00 8.99 ? 109 ILE A CA 1 ATOM 829 C C . ILE A 1 109 ? 68.639 2.333 -29.803 1.00 8.14 ? 109 ILE A C 1 ATOM 830 O O . ILE A 1 109 ? 67.575 2.776 -30.248 1.00 8.26 ? 109 ILE A O 1 ATOM 831 C CB . ILE A 1 109 ? 69.938 2.936 -31.818 1.00 9.11 ? 109 ILE A CB 1 ATOM 832 C CG1 . ILE A 1 109 ? 69.896 1.496 -32.350 1.00 8.51 ? 109 ILE A CG1 1 ATOM 833 C CG2 . ILE A 1 109 ? 71.156 3.671 -32.364 1.00 10.28 ? 109 ILE A CG2 1 ATOM 834 C CD1 . ILE A 1 109 ? 69.490 1.396 -33.807 1.00 7.42 ? 109 ILE A CD1 1 ATOM 835 N N . ASN A 1 110 ? 68.686 1.350 -28.909 1.00 7.80 ? 110 ASN A N 1 ATOM 836 C CA . ASN A 1 110 ? 67.459 0.694 -28.467 1.00 7.98 ? 110 ASN A CA 1 ATOM 837 C C . ASN A 1 110 ? 66.651 1.369 -27.358 1.00 8.38 ? 110 ASN A C 1 ATOM 838 O O . ASN A 1 110 ? 66.990 2.461 -26.901 1.00 8.10 ? 110 ASN A O 1 ATOM 839 C CB . ASN A 1 110 ? 67.749 -0.772 -28.106 1.00 8.02 ? 110 ASN A CB 1 ATOM 840 C CG . ASN A 1 110 ? 68.614 -0.930 -26.875 1.00 8.18 ? 110 ASN A CG 1 ATOM 841 O OD1 . ASN A 1 110 ? 68.697 -0.041 -26.031 1.00 9.70 ? 110 ASN A OD1 1 ATOM 842 N ND2 . ASN A 1 110 ? 69.248 -2.094 -26.756 1.00 6.92 ? 110 ASN A ND2 1 ATOM 843 N N . ALA A 1 111 ? 65.570 0.717 -26.940 1.00 6.68 ? 111 ALA A N 1 ATOM 844 C CA . ALA A 1 111 ? 64.691 1.265 -25.906 1.00 7.45 ? 111 ALA A CA 1 ATOM 845 C C . ALA A 1 111 ? 65.191 1.095 -24.470 1.00 6.83 ? 111 ALA A C 1 ATOM 846 O O . ALA A 1 111 ? 64.489 1.453 -23.517 1.00 8.21 ? 111 ALA A O 1 ATOM 847 C CB . ALA A 1 111 ? 63.291 0.676 -26.050 1.00 8.74 ? 111 ALA A CB 1 ATOM 848 N N . GLY A 1 112 ? 66.392 0.540 -24.323 1.00 6.56 ? 112 GLY A N 1 ATOM 849 C CA . GLY A 1 112 ? 66.998 0.365 -23.012 1.00 7.18 ? 112 GLY A CA 1 ATOM 850 C C . GLY A 1 112 ? 66.463 -0.690 -22.056 1.00 7.23 ? 112 GLY A C 1 ATOM 851 O O . GLY A 1 112 ? 67.015 -0.870 -20.972 1.00 7.93 ? 112 GLY A O 1 ATOM 852 N N . VAL A 1 113 ? 65.406 -1.397 -22.432 1.00 6.80 ? 113 VAL A N 1 ATOM 853 C CA . VAL A 1 113 ? 64.847 -2.410 -21.536 1.00 6.61 ? 113 VAL A CA 1 ATOM 854 C C . VAL A 1 113 ? 65.812 -3.583 -21.335 1.00 6.03 ? 113 VAL A C 1 ATOM 855 O O . VAL A 1 113 ? 66.320 -4.149 -22.299 1.00 7.64 ? 113 VAL A O 1 ATOM 856 C CB . VAL A 1 113 ? 63.503 -2.940 -22.075 1.00 6.63 ? 113 VAL A CB 1 ATOM 857 C CG1 . VAL A 1 113 ? 62.888 -3.922 -21.081 1.00 7.39 ? 113 VAL A CG1 1 ATOM 858 C CG2 . VAL A 1 113 ? 62.553 -1.776 -22.316 1.00 6.26 ? 113 VAL A CG2 1 ATOM 859 N N . TYR A 1 114 ? 66.064 -3.937 -20.075 1.00 6.67 ? 114 TYR A N 1 ATOM 860 C CA . TYR A 1 114 ? 66.967 -5.040 -19.761 1.00 7.21 ? 114 TYR A CA 1 ATOM 861 C C . TYR A 1 114 ? 66.286 -6.163 -18.991 1.00 8.38 ? 114 TYR A C 1 ATOM 862 O O . TYR A 1 114 ? 65.636 -5.926 -17.970 1.00 9.23 ? 114 TYR A O 1 ATOM 863 C CB . TYR A 1 114 ? 68.158 -4.546 -18.934 1.00 7.41 ? 114 TYR A CB 1 ATOM 864 C CG . TYR A 1 114 ? 69.139 -5.649 -18.584 1.00 7.23 ? 114 TYR A CG 1 ATOM 865 C CD1 . TYR A 1 114 ? 70.266 -5.881 -19.370 1.00 7.41 ? 114 TYR A CD1 1 ATOM 866 C CD2 . TYR A 1 114 ? 68.920 -6.482 -17.484 1.00 7.38 ? 114 TYR A CD2 1 ATOM 867 C CE1 . TYR A 1 114 ? 71.154 -6.916 -19.072 1.00 8.45 ? 114 TYR A CE1 1 ATOM 868 C CE2 . TYR A 1 114 ? 69.798 -7.520 -17.179 1.00 7.07 ? 114 TYR A CE2 1 ATOM 869 C CZ . TYR A 1 114 ? 70.914 -7.731 -17.976 1.00 7.93 ? 114 TYR A CZ 1 ATOM 870 O OH . TYR A 1 114 ? 71.795 -8.749 -17.678 1.00 8.07 ? 114 TYR A OH 1 ATOM 871 N N . ALA A 1 115 ? 66.458 -7.389 -19.477 1.00 7.87 ? 115 ALA A N 1 ATOM 872 C CA . ALA A 1 115 ? 65.885 -8.558 -18.827 1.00 8.66 ? 115 ALA A CA 1 ATOM 873 C C . ALA A 1 115 ? 66.810 -9.747 -19.024 1.00 8.58 ? 115 ALA A C 1 ATOM 874 O O . ALA A 1 115 ? 67.524 -9.824 -20.022 1.00 7.72 ? 115 ALA A O 1 ATOM 875 C CB . ALA A 1 115 ? 64.516 -8.873 -19.421 1.00 9.28 ? 115 ALA A CB 1 ATOM 876 N N . ARG A 1 116 ? 66.821 -10.658 -18.058 1.00 9.01 ? 116 ARG A N 1 ATOM 877 C CA . ARG A 1 116 ? 67.622 -11.863 -18.185 1.00 9.09 ? 116 ARG A CA 1 ATOM 878 C C . ARG A 1 116 ? 66.741 -12.838 -18.951 1.00 9.53 ? 116 ARG A C 1 ATOM 879 O O . ARG A 1 116 ? 65.513 -12.737 -18.912 1.00 9.99 ? 116 ARG A O 1 ATOM 880 C CB . ARG A 1 116 ? 67.965 -12.455 -16.815 1.00 9.72 ? 116 ARG A CB 1 ATOM 881 C CG . ARG A 1 116 ? 69.017 -11.687 -16.043 1.00 9.22 ? 116 ARG A CG 1 ATOM 882 C CD . ARG A 1 116 ? 69.416 -12.444 -14.789 1.00 10.60 ? 116 ARG A CD 1 ATOM 883 N NE . ARG A 1 116 ? 70.472 -11.763 -14.047 1.00 9.82 ? 116 ARG A NE 1 ATOM 884 C CZ . ARG A 1 116 ? 71.069 -12.266 -12.971 1.00 12.46 ? 116 ARG A CZ 1 ATOM 885 N NH1 . ARG A 1 116 ? 70.715 -13.461 -12.508 1.00 11.69 ? 116 ARG A NH1 1 ATOM 886 N NH2 . ARG A 1 116 ? 72.021 -11.575 -12.357 1.00 13.68 ? 116 ARG A NH2 1 ATOM 887 N N . ALA A 1 117 ? 67.360 -13.786 -19.638 1.00 9.18 ? 117 ALA A N 1 ATOM 888 C CA . ALA A 1 117 ? 66.600 -14.755 -20.408 1.00 8.96 ? 117 ALA A CA 1 ATOM 889 C C . ALA A 1 117 ? 65.753 -15.677 -19.536 1.00 10.07 ? 117 ALA A C 1 ATOM 890 O O . ALA A 1 117 ? 66.073 -15.931 -18.372 1.00 11.87 ? 117 ALA A O 1 ATOM 891 C CB . ALA A 1 117 ? 67.544 -15.588 -21.270 1.00 9.00 ? 117 ALA A CB 1 ATOM 892 N N . ASN A 1 118 ? 64.662 -16.160 -20.121 1.00 10.50 ? 118 ASN A N 1 ATOM 893 C CA . ASN A 1 118 ? 63.760 -17.108 -19.472 1.00 10.82 ? 118 ASN A CA 1 ATOM 894 C C . ASN A 1 118 ? 64.684 -18.243 -19.003 1.00 12.71 ? 118 ASN A C 1 ATOM 895 O O . ASN A 1 118 ? 65.389 -18.840 -19.815 1.00 13.67 ? 118 ASN A O 1 ATOM 896 C CB . ASN A 1 118 ? 62.769 -17.622 -20.522 1.00 10.24 ? 118 ASN A CB 1 ATOM 897 C CG . ASN A 1 118 ? 61.773 -18.619 -19.966 1.00 11.95 ? 118 ASN A CG 1 ATOM 898 O OD1 . ASN A 1 118 ? 62.063 -19.355 -19.027 1.00 14.94 ? 118 ASN A OD1 1 ATOM 899 N ND2 . ASN A 1 118 ? 60.593 -18.656 -20.575 1.00 13.45 ? 118 ASN A ND2 1 ATOM 900 N N . THR A 1 119 ? 64.692 -18.537 -17.706 1.00 13.18 ? 119 THR A N 1 ATOM 901 C CA . THR A 1 119 ? 65.575 -19.581 -17.180 1.00 14.07 ? 119 THR A CA 1 ATOM 902 C C . THR A 1 119 ? 65.281 -20.997 -17.668 1.00 15.34 ? 119 THR A C 1 ATOM 903 O O . THR A 1 119 ? 66.062 -21.913 -17.411 1.00 16.24 ? 119 THR A O 1 ATOM 904 C CB . THR A 1 119 ? 65.566 -19.603 -15.633 1.00 15.32 ? 119 THR A CB 1 ATOM 905 O OG1 . THR A 1 119 ? 64.235 -19.843 -15.162 1.00 16.28 ? 119 THR A OG1 1 ATOM 906 C CG2 . THR A 1 119 ? 66.074 -18.284 -15.078 1.00 15.22 ? 119 THR A CG2 1 ATOM 907 N N . SER A 1 120 ? 64.172 -21.175 -18.378 1.00 15.93 ? 120 SER A N 1 ATOM 908 C CA . SER A 1 120 ? 63.787 -22.497 -18.870 1.00 17.84 ? 120 SER A CA 1 ATOM 909 C C . SER A 1 120 ? 64.178 -22.787 -20.318 1.00 18.17 ? 120 SER A C 1 ATOM 910 O O . SER A 1 120 ? 63.994 -23.906 -20.795 1.00 18.82 ? 120 SER A O 1 ATOM 911 C CB . SER A 1 120 ? 62.272 -22.683 -18.727 1.00 17.69 ? 120 SER A CB 1 ATOM 912 O OG . SER A 1 120 ? 61.856 -22.512 -17.384 1.00 19.93 ? 120 SER A OG 1 ATOM 913 N N . ILE A 1 121 ? 64.726 -21.796 -21.015 1.00 18.25 ? 121 ILE A N 1 ATOM 914 C CA . ILE A 1 121 ? 65.092 -21.981 -22.417 1.00 18.61 ? 121 ILE A CA 1 ATOM 915 C C . ILE A 1 121 ? 66.485 -22.540 -22.697 1.00 18.41 ? 121 ILE A C 1 ATOM 916 O O . ILE A 1 121 ? 66.779 -22.919 -23.829 1.00 18.07 ? 121 ILE A O 1 ATOM 917 C CB . ILE A 1 121 ? 64.941 -20.659 -23.198 1.00 19.39 ? 121 ILE A CB 1 ATOM 918 C CG1 . ILE A 1 121 ? 65.901 -19.608 -22.638 1.00 21.43 ? 121 ILE A CG1 1 ATOM 919 C CG2 . ILE A 1 121 ? 63.504 -20.170 -23.107 1.00 19.14 ? 121 ILE A CG2 1 ATOM 920 C CD1 . ILE A 1 121 ? 65.793 -18.253 -23.306 1.00 23.20 ? 121 ILE A CD1 1 ATOM 921 N N . TYR A 1 122 ? 67.341 -22.601 -21.682 1.00 17.83 ? 122 TYR A N 1 ATOM 922 C CA . TYR A 1 122 ? 68.696 -23.103 -21.884 1.00 17.54 ? 122 TYR A CA 1 ATOM 923 C C . TYR A 1 122 ? 68.781 -24.592 -22.218 1.00 19.36 ? 122 TYR A C 1 ATOM 924 O O . TYR A 1 122 ? 69.583 -24.999 -23.056 1.00 19.43 ? 122 TYR A O 1 ATOM 925 C CB . TYR A 1 122 ? 69.566 -22.817 -20.654 1.00 15.22 ? 122 TYR A CB 1 ATOM 926 C CG . TYR A 1 122 ? 69.696 -21.347 -20.323 1.00 13.74 ? 122 TYR A CG 1 ATOM 927 C CD1 . TYR A 1 122 ? 68.803 -20.726 -19.451 1.00 13.11 ? 122 TYR A CD1 1 ATOM 928 C CD2 . TYR A 1 122 ? 70.705 -20.572 -20.894 1.00 13.03 ? 122 TYR A CD2 1 ATOM 929 C CE1 . TYR A 1 122 ? 68.910 -19.365 -19.153 1.00 13.81 ? 122 TYR A CE1 1 ATOM 930 C CE2 . TYR A 1 122 ? 70.820 -19.210 -20.606 1.00 13.93 ? 122 TYR A CE2 1 ATOM 931 C CZ . TYR A 1 122 ? 69.921 -18.615 -19.735 1.00 12.46 ? 122 TYR A CZ 1 ATOM 932 O OH . TYR A 1 122 ? 70.029 -17.274 -19.448 1.00 11.38 ? 122 TYR A OH 1 ATOM 933 N N . SER A 1 123 ? 67.949 -25.402 -21.572 1.00 21.03 ? 123 SER A N 1 ATOM 934 C CA . SER A 1 123 ? 67.974 -26.845 -21.803 1.00 23.63 ? 123 SER A CA 1 ATOM 935 C C . SER A 1 123 ? 67.738 -27.353 -23.222 1.00 24.22 ? 123 SER A C 1 ATOM 936 O O . SER A 1 123 ? 68.365 -28.322 -23.635 1.00 25.56 ? 123 SER A O 1 ATOM 937 C CB . SER A 1 123 ? 67.005 -27.547 -20.851 1.00 24.52 ? 123 SER A CB 1 ATOM 938 O OG . SER A 1 123 ? 67.667 -27.926 -19.655 1.00 29.68 ? 123 SER A OG 1 ATOM 939 N N . ALA A 1 124 ? 66.857 -26.708 -23.974 1.00 24.65 ? 124 ALA A N 1 ATOM 940 C CA . ALA A 1 124 ? 66.563 -27.160 -25.331 1.00 25.81 ? 124 ALA A CA 1 ATOM 941 C C . ALA A 1 124 ? 67.205 -26.323 -26.429 1.00 25.48 ? 124 ALA A C 1 ATOM 942 O O . ALA A 1 124 ? 66.847 -26.445 -27.592 1.00 26.92 ? 124 ALA A O 1 ATOM 943 C CB . ALA A 1 124 ? 65.049 -27.200 -25.527 1.00 26.24 ? 124 ALA A CB 1 ATOM 944 N N . SER A 1 125 ? 68.162 -25.482 -26.057 1.00 23.37 ? 125 SER A N 1 ATOM 945 C CA . SER A 1 125 ? 68.833 -24.593 -27.007 1.00 21.33 ? 125 SER A CA 1 ATOM 946 C C . SER A 1 125 ? 69.847 -25.229 -27.964 1.00 19.97 ? 125 SER A C 1 ATOM 947 O O . SER A 1 125 ? 70.160 -24.657 -29.009 1.00 18.86 ? 125 SER A O 1 ATOM 948 C CB . SER A 1 125 ? 69.537 -23.471 -26.243 1.00 21.05 ? 125 SER A CB 1 ATOM 949 O OG . SER A 1 125 ? 70.546 -24.018 -25.417 1.00 20.25 ? 125 SER A OG 1 ATOM 950 N N . GLY A 1 126 ? 70.369 -26.398 -27.614 1.00 18.96 ? 126 GLY A N 1 ATOM 951 C CA . GLY A 1 126 ? 71.356 -27.038 -28.468 1.00 17.25 ? 126 GLY A CA 1 ATOM 952 C C . GLY A 1 126 ? 72.756 -26.723 -27.968 1.00 15.88 ? 126 GLY A C 1 ATOM 953 O O . GLY A 1 126 ? 73.754 -27.071 -28.598 1.00 14.74 ? 126 GLY A O 1 ATOM 954 N N . VAL A 1 127 ? 72.818 -26.044 -26.828 1.00 15.21 ? 127 VAL A N 1 ATOM 955 C CA . VAL A 1 127 ? 74.082 -25.675 -26.196 1.00 14.54 ? 127 VAL A CA 1 ATOM 956 C C . VAL A 1 127 ? 74.078 -26.219 -24.769 1.00 15.51 ? 127 VAL A C 1 ATOM 957 O O . VAL A 1 127 ? 73.062 -26.149 -24.081 1.00 14.89 ? 127 VAL A O 1 ATOM 958 C CB . VAL A 1 127 ? 74.255 -24.131 -26.134 1.00 13.45 ? 127 VAL A CB 1 ATOM 959 C CG1 . VAL A 1 127 ? 75.445 -23.768 -25.250 1.00 13.28 ? 127 VAL A CG1 1 ATOM 960 C CG2 . VAL A 1 127 ? 74.448 -23.571 -27.533 1.00 14.16 ? 127 VAL A CG2 1 ATOM 961 N N . ASP A 1 128 ? 75.206 -26.771 -24.333 1.00 16.13 ? 128 ASP A N 1 ATOM 962 C CA . ASP A 1 128 ? 75.321 -27.298 -22.975 1.00 18.66 ? 128 ASP A CA 1 ATOM 963 C C . ASP A 1 128 ? 75.799 -26.128 -22.124 1.00 16.83 ? 128 ASP A C 1 ATOM 964 O O . ASP A 1 128 ? 77.000 -25.898 -21.988 1.00 18.60 ? 128 ASP A O 1 ATOM 965 C CB . ASP A 1 128 ? 76.344 -28.437 -22.927 1.00 21.41 ? 128 ASP A CB 1 ATOM 966 C CG . ASP A 1 128 ? 76.427 -29.092 -21.559 1.00 27.40 ? 128 ASP A CG 1 ATOM 967 O OD1 . ASP A 1 128 ? 75.827 -28.559 -20.601 1.00 30.42 ? 128 ASP A OD1 1 ATOM 968 O OD2 . ASP A 1 128 ? 77.099 -30.140 -21.440 1.00 30.30 ? 128 ASP A OD2 1 ATOM 969 N N . TRP A 1 129 ? 74.853 -25.389 -21.557 1.00 16.37 ? 129 TRP A N 1 ATOM 970 C CA . TRP A 1 129 ? 75.176 -24.213 -20.758 1.00 15.10 ? 129 TRP A CA 1 ATOM 971 C C . TRP A 1 129 ? 75.733 -24.458 -19.365 1.00 15.53 ? 129 TRP A C 1 ATOM 972 O O . TRP A 1 129 ? 75.289 -25.354 -18.648 1.00 16.42 ? 129 TRP A O 1 ATOM 973 C CB . TRP A 1 129 ? 73.943 -23.313 -20.613 1.00 15.51 ? 129 TRP A CB 1 ATOM 974 C CG . TRP A 1 129 ? 73.392 -22.792 -21.902 1.00 14.24 ? 129 TRP A CG 1 ATOM 975 C CD1 . TRP A 1 129 ? 72.455 -23.387 -22.695 1.00 14.45 ? 129 TRP A CD1 1 ATOM 976 C CD2 . TRP A 1 129 ? 73.743 -21.563 -22.545 1.00 14.17 ? 129 TRP A CD2 1 ATOM 977 N NE1 . TRP A 1 129 ? 72.198 -22.603 -23.796 1.00 13.96 ? 129 TRP A NE1 1 ATOM 978 C CE2 . TRP A 1 129 ? 72.976 -21.477 -23.728 1.00 13.96 ? 129 TRP A CE2 1 ATOM 979 C CE3 . TRP A 1 129 ? 74.633 -20.525 -22.238 1.00 14.79 ? 129 TRP A CE3 1 ATOM 980 C CZ2 . TRP A 1 129 ? 73.072 -20.392 -24.607 1.00 14.13 ? 129 TRP A CZ2 1 ATOM 981 C CZ3 . TRP A 1 129 ? 74.729 -19.445 -23.112 1.00 14.19 ? 129 TRP A CZ3 1 ATOM 982 C CH2 . TRP A 1 129 ? 73.952 -19.389 -24.282 1.00 13.36 ? 129 TRP A CH2 1 ATOM 983 N N . ASP A 1 130 ? 76.711 -23.636 -18.997 1.00 15.35 ? 130 ASP A N 1 ATOM 984 C CA . ASP A 1 130 ? 77.323 -23.665 -17.674 1.00 14.82 ? 130 ASP A CA 1 ATOM 985 C C . ASP A 1 130 ? 76.532 -22.567 -16.967 1.00 15.49 ? 130 ASP A C 1 ATOM 986 O O . ASP A 1 130 ? 76.850 -21.384 -17.103 1.00 13.47 ? 130 ASP A O 1 ATOM 987 C CB . ASP A 1 130 ? 78.800 -23.265 -17.763 1.00 16.27 ? 130 ASP A CB 1 ATOM 988 C CG . ASP A 1 130 ? 79.493 -23.261 -16.411 1.00 17.39 ? 130 ASP A CG 1 ATOM 989 O OD1 . ASP A 1 130 ? 78.812 -23.049 -15.386 1.00 17.91 ? 130 ASP A OD1 1 ATOM 990 O OD2 . ASP A 1 130 ? 80.728 -23.454 -16.377 1.00 20.39 ? 130 ASP A OD2 1 ATOM 991 N N . MET A 1 131 ? 75.493 -22.949 -16.230 1.00 15.28 ? 131 MET A N 1 ATOM 992 C CA . MET A 1 131 ? 74.654 -21.962 -15.561 1.00 16.03 ? 131 MET A CA 1 ATOM 993 C C . MET A 1 131 ? 75.358 -21.089 -14.532 1.00 15.48 ? 131 MET A C 1 ATOM 994 O O . MET A 1 131 ? 74.974 -19.934 -14.340 1.00 14.96 ? 131 MET A O 1 ATOM 995 C CB . MET A 1 131 ? 73.429 -22.635 -14.938 1.00 17.79 ? 131 MET A CB 1 ATOM 996 C CG . MET A 1 131 ? 72.463 -23.216 -15.970 1.00 20.04 ? 131 MET A CG 1 ATOM 997 S SD . MET A 1 131 ? 72.106 -22.094 -17.361 1.00 23.73 ? 131 MET A SD 1 ATOM 998 C CE . MET A 1 131 ? 71.238 -20.763 -16.539 1.00 18.83 ? 131 MET A CE 1 ATOM 999 N N . ASP A 1 132 ? 76.376 -21.619 -13.862 1.00 15.12 ? 132 ASP A N 1 ATOM 1000 C CA . ASP A 1 132 ? 77.099 -20.801 -12.897 1.00 15.73 ? 132 ASP A CA 1 ATOM 1001 C C . ASP A 1 132 ? 77.768 -19.662 -13.660 1.00 13.73 ? 132 ASP A C 1 ATOM 1002 O O . ASP A 1 132 ? 77.773 -18.515 -13.206 1.00 14.47 ? 132 ASP A O 1 ATOM 1003 C CB . ASP A 1 132 ? 78.168 -21.614 -12.159 1.00 18.65 ? 132 ASP A CB 1 ATOM 1004 C CG . ASP A 1 132 ? 77.576 -22.658 -11.232 1.00 21.60 ? 132 ASP A CG 1 ATOM 1005 O OD1 . ASP A 1 132 ? 76.548 -22.373 -10.585 1.00 22.05 ? 132 ASP A OD1 1 ATOM 1006 O OD2 . ASP A 1 132 ? 78.151 -23.763 -11.137 1.00 25.81 ? 132 ASP A OD2 1 ATOM 1007 N N . LEU A 1 133 ? 78.326 -19.986 -14.826 1.00 13.11 ? 133 LEU A N 1 ATOM 1008 C CA . LEU A 1 133 ? 78.999 -18.996 -15.659 1.00 11.46 ? 133 LEU A CA 1 ATOM 1009 C C . LEU A 1 133 ? 77.992 -18.014 -16.247 1.00 10.05 ? 133 LEU A C 1 ATOM 1010 O O . LEU A 1 133 ? 78.259 -16.817 -16.332 1.00 10.42 ? 133 LEU A O 1 ATOM 1011 C CB . LEU A 1 133 ? 79.780 -19.687 -16.784 1.00 12.47 ? 133 LEU A CB 1 ATOM 1012 C CG . LEU A 1 133 ? 80.536 -18.779 -17.761 1.00 12.66 ? 133 LEU A CG 1 ATOM 1013 C CD1 . LEU A 1 133 ? 81.478 -17.844 -16.998 1.00 13.12 ? 133 LEU A CD1 1 ATOM 1014 C CD2 . LEU A 1 133 ? 81.306 -19.642 -18.755 1.00 14.68 ? 133 LEU A CD2 1 ATOM 1015 N N . VAL A 1 134 ? 76.834 -18.523 -16.655 1.00 10.19 ? 134 VAL A N 1 ATOM 1016 C CA . VAL A 1 134 ? 75.799 -17.663 -17.211 1.00 10.46 ? 134 VAL A CA 1 ATOM 1017 C C . VAL A 1 134 ? 75.441 -16.559 -16.220 1.00 10.87 ? 134 VAL A C 1 ATOM 1018 O O . VAL A 1 134 ? 75.460 -15.378 -16.564 1.00 11.78 ? 134 VAL A O 1 ATOM 1019 C CB . VAL A 1 134 ? 74.520 -18.464 -17.555 1.00 11.05 ? 134 VAL A CB 1 ATOM 1020 C CG1 . VAL A 1 134 ? 73.369 -17.509 -17.860 1.00 9.83 ? 134 VAL A CG1 1 ATOM 1021 C CG2 . VAL A 1 134 ? 74.783 -19.368 -18.755 1.00 10.76 ? 134 VAL A CG2 1 ATOM 1022 N N . ASN A 1 135 ? 75.129 -16.938 -14.984 1.00 11.26 ? 135 ASN A N 1 ATOM 1023 C CA . ASN A 1 135 ? 74.764 -15.944 -13.983 1.00 11.38 ? 135 ASN A CA 1 ATOM 1024 C C . ASN A 1 135 ? 75.918 -15.018 -13.618 1.00 10.87 ? 135 ASN A C 1 ATOM 1025 O O . ASN A 1 135 ? 75.711 -13.828 -13.377 1.00 10.35 ? 135 ASN A O 1 ATOM 1026 C CB . ASN A 1 135 ? 74.206 -16.626 -12.736 1.00 11.64 ? 135 ASN A CB 1 ATOM 1027 C CG . ASN A 1 135 ? 72.797 -17.144 -12.944 1.00 13.40 ? 135 ASN A CG 1 ATOM 1028 O OD1 . ASN A 1 135 ? 72.226 -17.007 -14.025 1.00 12.41 ? 135 ASN A OD1 1 ATOM 1029 N ND2 . ASN A 1 135 ? 72.238 -17.742 -11.898 1.00 15.04 ? 135 ASN A ND2 1 ATOM 1030 N N . GLN A 1 136 ? 77.134 -15.553 -13.578 1.00 11.24 ? 136 GLN A N 1 ATOM 1031 C CA . GLN A 1 136 ? 78.297 -14.728 -13.271 1.00 11.35 ? 136 GLN A CA 1 ATOM 1032 C C . GLN A 1 136 ? 78.450 -13.671 -14.356 1.00 10.67 ? 136 GLN A C 1 ATOM 1033 O O . GLN A 1 136 ? 78.824 -12.530 -14.082 1.00 10.15 ? 136 GLN A O 1 ATOM 1034 C CB . GLN A 1 136 ? 79.564 -15.581 -13.223 1.00 11.05 ? 136 GLN A CB 1 ATOM 1035 C CG . GLN A 1 136 ? 79.708 -16.415 -11.968 1.00 15.13 ? 136 GLN A CG 1 ATOM 1036 C CD . GLN A 1 136 ? 80.750 -17.498 -12.126 1.00 17.85 ? 136 GLN A CD 1 ATOM 1037 O OE1 . GLN A 1 136 ? 81.580 -17.447 -13.037 1.00 19.47 ? 136 GLN A OE1 1 ATOM 1038 N NE2 . GLN A 1 136 ? 80.720 -18.484 -11.237 1.00 17.71 ? 136 GLN A NE2 1 ATOM 1039 N N . THR A 1 137 ? 78.146 -14.061 -15.592 1.00 9.90 ? 137 THR A N 1 ATOM 1040 C CA . THR A 1 137 ? 78.258 -13.156 -16.726 1.00 9.48 ? 137 THR A CA 1 ATOM 1041 C C . THR A 1 137 ? 77.158 -12.096 -16.701 1.00 9.88 ? 137 THR A C 1 ATOM 1042 O O . THR A 1 137 ? 77.405 -10.936 -17.027 1.00 8.44 ? 137 THR A O 1 ATOM 1043 C CB . THR A 1 137 ? 78.232 -13.945 -18.051 1.00 10.38 ? 137 THR A CB 1 ATOM 1044 O OG1 . THR A 1 137 ? 79.311 -14.892 -18.052 1.00 10.77 ? 137 THR A OG1 1 ATOM 1045 C CG2 . THR A 1 137 ? 78.400 -13.006 -19.239 1.00 10.85 ? 137 THR A CG2 1 ATOM 1046 N N . TYR A 1 138 ? 75.947 -12.485 -16.313 1.00 9.07 ? 138 TYR A N 1 ATOM 1047 C CA . TYR A 1 138 ? 74.858 -11.516 -16.213 1.00 9.40 ? 138 TYR A CA 1 ATOM 1048 C C . TYR A 1 138 ? 75.268 -10.452 -15.190 1.00 9.56 ? 138 TYR A C 1 ATOM 1049 O O . TYR A 1 138 ? 75.095 -9.255 -15.420 1.00 8.99 ? 138 TYR A O 1 ATOM 1050 C CB . TYR A 1 138 ? 73.561 -12.193 -15.752 1.00 8.65 ? 138 TYR A CB 1 ATOM 1051 C CG . TYR A 1 138 ? 72.739 -12.831 -16.857 1.00 9.03 ? 138 TYR A CG 1 ATOM 1052 C CD1 . TYR A 1 138 ? 72.248 -14.130 -16.724 1.00 9.83 ? 138 TYR A CD1 1 ATOM 1053 C CD2 . TYR A 1 138 ? 72.425 -12.125 -18.016 1.00 9.23 ? 138 TYR A CD2 1 ATOM 1054 C CE1 . TYR A 1 138 ? 71.462 -14.712 -17.719 1.00 10.21 ? 138 TYR A CE1 1 ATOM 1055 C CE2 . TYR A 1 138 ? 71.636 -12.698 -19.021 1.00 8.70 ? 138 TYR A CE2 1 ATOM 1056 C CZ . TYR A 1 138 ? 71.160 -13.990 -18.864 1.00 9.57 ? 138 TYR A CZ 1 ATOM 1057 O OH . TYR A 1 138 ? 70.380 -14.559 -19.846 1.00 10.35 ? 138 TYR A OH 1 ATOM 1058 N N . GLU A 1 139 ? 75.820 -10.899 -14.062 1.00 10.39 ? 139 GLU A N 1 ATOM 1059 C CA . GLU A 1 139 ? 76.253 -9.993 -13.000 1.00 11.35 ? 139 GLU A CA 1 ATOM 1060 C C . GLU A 1 139 ? 77.340 -9.037 -13.496 1.00 9.51 ? 139 GLU A C 1 ATOM 1061 O O . GLU A 1 139 ? 77.316 -7.846 -13.196 1.00 11.64 ? 139 GLU A O 1 ATOM 1062 C CB . GLU A 1 139 ? 76.766 -10.806 -11.803 1.00 12.36 ? 139 GLU A CB 1 ATOM 1063 C CG . GLU A 1 139 ? 75.689 -11.666 -11.145 1.00 16.94 ? 139 GLU A CG 1 ATOM 1064 C CD . GLU A 1 139 ? 76.255 -12.714 -10.201 1.00 22.11 ? 139 GLU A CD 1 ATOM 1065 O OE1 . GLU A 1 139 ? 75.455 -13.424 -9.552 1.00 24.98 ? 139 GLU A OE1 1 ATOM 1066 O OE2 . GLU A 1 139 ? 77.494 -12.832 -10.110 1.00 23.69 ? 139 GLU A OE2 1 ATOM 1067 N N . TRP A 1 140 ? 78.283 -9.572 -14.267 1.00 9.88 ? 140 TRP A N 1 ATOM 1068 C CA . TRP A 1 140 ? 79.387 -8.796 -14.832 1.00 9.94 ? 140 TRP A CA 1 ATOM 1069 C C . TRP A 1 140 ? 78.844 -7.654 -15.703 1.00 9.54 ? 140 TRP A C 1 ATOM 1070 O O . TRP A 1 140 ? 79.311 -6.515 -15.621 1.00 11.20 ? 140 TRP A O 1 ATOM 1071 C CB . TRP A 1 140 ? 80.259 -9.738 -15.666 1.00 10.38 ? 140 TRP A CB 1 ATOM 1072 C CG . TRP A 1 140 ? 81.524 -9.171 -16.256 1.00 11.24 ? 140 TRP A CG 1 ATOM 1073 C CD1 . TRP A 1 140 ? 82.767 -9.152 -15.682 1.00 11.66 ? 140 TRP A CD1 1 ATOM 1074 C CD2 . TRP A 1 140 ? 81.694 -8.680 -17.590 1.00 10.50 ? 140 TRP A CD2 1 ATOM 1075 N NE1 . TRP A 1 140 ? 83.701 -8.695 -16.585 1.00 10.80 ? 140 TRP A NE1 1 ATOM 1076 C CE2 . TRP A 1 140 ? 83.067 -8.398 -17.764 1.00 10.72 ? 140 TRP A CE2 1 ATOM 1077 C CE3 . TRP A 1 140 ? 80.816 -8.459 -18.661 1.00 10.73 ? 140 TRP A CE3 1 ATOM 1078 C CZ2 . TRP A 1 140 ? 83.584 -7.909 -18.968 1.00 12.54 ? 140 TRP A CZ2 1 ATOM 1079 C CZ3 . TRP A 1 140 ? 81.332 -7.973 -19.858 1.00 12.40 ? 140 TRP A CZ3 1 ATOM 1080 C CH2 . TRP A 1 140 ? 82.703 -7.705 -20.000 1.00 11.39 ? 140 TRP A CH2 1 ATOM 1081 N N . VAL A 1 141 ? 77.857 -7.964 -16.539 1.00 9.07 ? 141 VAL A N 1 ATOM 1082 C CA . VAL A 1 141 ? 77.244 -6.964 -17.405 1.00 9.88 ? 141 VAL A CA 1 ATOM 1083 C C . VAL A 1 141 ? 76.411 -5.974 -16.592 1.00 9.12 ? 141 VAL A C 1 ATOM 1084 O O . VAL A 1 141 ? 76.534 -4.760 -16.750 1.00 9.81 ? 141 VAL A O 1 ATOM 1085 C CB . VAL A 1 141 ? 76.318 -7.625 -18.455 1.00 8.47 ? 141 VAL A CB 1 ATOM 1086 C CG1 . VAL A 1 141 ? 75.568 -6.554 -19.247 1.00 9.22 ? 141 VAL A CG1 1 ATOM 1087 C CG2 . VAL A 1 141 ? 77.133 -8.501 -19.388 1.00 10.33 ? 141 VAL A CG2 1 ATOM 1088 N N . GLU A 1 142 ? 75.566 -6.507 -15.715 1.00 9.50 ? 142 GLU A N 1 ATOM 1089 C CA . GLU A 1 142 ? 74.684 -5.688 -14.895 1.00 9.49 ? 142 GLU A CA 1 ATOM 1090 C C . GLU A 1 142 ? 75.403 -4.712 -13.975 1.00 9.41 ? 142 GLU A C 1 ATOM 1091 O O . GLU A 1 142 ? 74.940 -3.590 -13.772 1.00 10.13 ? 142 GLU A O 1 ATOM 1092 C CB . GLU A 1 142 ? 73.750 -6.598 -14.095 1.00 10.54 ? 142 GLU A CB 1 ATOM 1093 C CG . GLU A 1 142 ? 72.761 -7.329 -14.995 1.00 8.97 ? 142 GLU A CG 1 ATOM 1094 C CD . GLU A 1 142 ? 72.225 -8.601 -14.384 1.00 10.20 ? 142 GLU A CD 1 ATOM 1095 O OE1 . GLU A 1 142 ? 71.555 -9.369 -15.112 1.00 9.27 ? 142 GLU A OE1 1 ATOM 1096 O OE2 . GLU A 1 142 ? 72.468 -8.834 -13.181 1.00 11.97 ? 142 GLU A OE2 1 ATOM 1097 N N . ASP A 1 143 ? 76.539 -5.128 -13.430 1.00 9.64 ? 143 ASP A N 1 ATOM 1098 C CA . ASP A 1 143 ? 77.293 -4.254 -12.546 1.00 12.01 ? 143 ASP A CA 1 ATOM 1099 C C . ASP A 1 143 ? 77.940 -3.105 -13.311 1.00 11.67 ? 143 ASP A C 1 ATOM 1100 O O . ASP A 1 143 ? 78.433 -2.152 -12.706 1.00 11.86 ? 143 ASP A O 1 ATOM 1101 C CB . ASP A 1 143 ? 78.371 -5.044 -11.796 1.00 14.02 ? 143 ASP A CB 1 ATOM 1102 C CG . ASP A 1 143 ? 77.790 -5.964 -10.735 1.00 17.56 ? 143 ASP A CG 1 ATOM 1103 O OD1 . ASP A 1 143 ? 76.598 -5.807 -10.389 1.00 20.71 ? 143 ASP A OD1 1 ATOM 1104 O OD2 . ASP A 1 143 ? 78.530 -6.838 -10.238 1.00 19.75 ? 143 ASP A OD2 1 ATOM 1105 N N . THR A 1 144 ? 77.921 -3.181 -14.640 1.00 11.11 ? 144 THR A N 1 ATOM 1106 C CA . THR A 1 144 ? 78.533 -2.140 -15.455 1.00 10.71 ? 144 THR A CA 1 ATOM 1107 C C . THR A 1 144 ? 77.554 -1.208 -16.172 1.00 11.38 ? 144 THR A C 1 ATOM 1108 O O . THR A 1 144 ? 77.789 0.003 -16.228 1.00 12.44 ? 144 THR A O 1 ATOM 1109 C CB . THR A 1 144 ? 79.478 -2.753 -16.521 1.00 12.94 ? 144 THR A CB 1 ATOM 1110 O OG1 . THR A 1 144 ? 80.360 -3.699 -15.900 1.00 14.28 ? 144 THR A OG1 1 ATOM 1111 C CG2 . THR A 1 144 ? 80.316 -1.662 -17.185 1.00 12.14 ? 144 THR A CG2 1 ATOM 1112 N N . ILE A 1 145 ? 76.462 -1.755 -16.709 1.00 10.52 ? 145 ILE A N 1 ATOM 1113 C CA . ILE A 1 145 ? 75.507 -0.934 -17.460 1.00 10.06 ? 145 ILE A CA 1 ATOM 1114 C C . ILE A 1 145 ? 74.004 -1.115 -17.212 1.00 9.15 ? 145 ILE A C 1 ATOM 1115 O O . ILE A 1 145 ? 73.199 -0.665 -18.029 1.00 9.30 ? 145 ILE A O 1 ATOM 1116 C CB . ILE A 1 145 ? 75.724 -1.099 -18.988 1.00 9.00 ? 145 ILE A CB 1 ATOM 1117 C CG1 . ILE A 1 145 ? 75.504 -2.562 -19.389 1.00 9.27 ? 145 ILE A CG1 1 ATOM 1118 C CG2 . ILE A 1 145 ? 77.128 -0.647 -19.375 1.00 11.21 ? 145 ILE A CG2 1 ATOM 1119 C CD1 . ILE A 1 145 ? 75.549 -2.806 -20.893 1.00 8.97 ? 145 ILE A CD1 1 ATOM 1120 N N . VAL A 1 146 ? 73.610 -1.746 -16.109 1.00 8.51 ? 146 VAL A N 1 ATOM 1121 C CA . VAL A 1 146 ? 72.183 -1.937 -15.840 1.00 9.00 ? 146 VAL A CA 1 ATOM 1122 C C . VAL A 1 146 ? 71.774 -1.242 -14.544 1.00 10.64 ? 146 VAL A C 1 ATOM 1123 O O . VAL A 1 146 ? 72.473 -1.334 -13.530 1.00 10.33 ? 146 VAL A O 1 ATOM 1124 C CB . VAL A 1 146 ? 71.825 -3.437 -15.773 1.00 9.28 ? 146 VAL A CB 1 ATOM 1125 C CG1 . VAL A 1 146 ? 70.326 -3.611 -15.546 1.00 9.21 ? 146 VAL A CG1 1 ATOM 1126 C CG2 . VAL A 1 146 ? 72.242 -4.118 -17.077 1.00 10.53 ? 146 VAL A CG2 1 ATOM 1127 N N . TYR A 1 147 ? 70.635 -0.554 -14.579 1.00 10.02 ? 147 TYR A N 1 ATOM 1128 C CA . TYR A 1 147 ? 70.167 0.203 -13.421 1.00 11.18 ? 147 TYR A CA 1 ATOM 1129 C C . TYR A 1 147 ? 68.735 -0.062 -13.000 1.00 12.22 ? 147 TYR A C 1 ATOM 1130 O O . TYR A 1 147 ? 67.893 -0.436 -13.814 1.00 12.68 ? 147 TYR A O 1 ATOM 1131 C CB . TYR A 1 147 ? 70.296 1.705 -13.705 1.00 11.50 ? 147 TYR A CB 1 ATOM 1132 C CG . TYR A 1 147 ? 71.620 2.076 -14.309 1.00 10.65 ? 147 TYR A CG 1 ATOM 1133 C CD1 . TYR A 1 147 ? 71.896 1.800 -15.647 1.00 11.08 ? 147 TYR A CD1 1 ATOM 1134 C CD2 . TYR A 1 147 ? 72.638 2.603 -13.519 1.00 10.59 ? 147 TYR A CD2 1 ATOM 1135 C CE1 . TYR A 1 147 ? 73.154 2.023 -16.180 1.00 12.00 ? 147 TYR A CE1 1 ATOM 1136 C CE2 . TYR A 1 147 ? 73.901 2.831 -14.043 1.00 11.09 ? 147 TYR A CE2 1 ATOM 1137 C CZ . TYR A 1 147 ? 74.154 2.535 -15.371 1.00 11.58 ? 147 TYR A CZ 1 ATOM 1138 O OH . TYR A 1 147 ? 75.418 2.713 -15.874 1.00 12.88 ? 147 TYR A OH 1 ATOM 1139 N N . LYS A 1 148 ? 68.474 0.138 -11.711 1.00 12.62 ? 148 LYS A N 1 ATOM 1140 C CA . LYS A 1 148 ? 67.131 0.006 -11.168 1.00 12.78 ? 148 LYS A CA 1 ATOM 1141 C C . LYS A 1 148 ? 66.554 1.376 -11.519 1.00 12.43 ? 148 LYS A C 1 ATOM 1142 O O . LYS A 1 148 ? 67.059 2.404 -11.070 1.00 13.02 ? 148 LYS A O 1 ATOM 1143 C CB . LYS A 1 148 ? 67.187 -0.182 -9.650 1.00 13.49 ? 148 LYS A CB 1 ATOM 1144 C CG . LYS A 1 148 ? 65.822 -0.314 -8.989 1.00 16.38 ? 148 LYS A CG 1 ATOM 1145 C CD . LYS A 1 148 ? 65.955 -0.347 -7.474 1.00 19.88 ? 148 LYS A CD 1 ATOM 1146 C CE . LYS A 1 148 ? 64.596 -0.404 -6.791 1.00 22.43 ? 148 LYS A CE 1 ATOM 1147 N NZ . LYS A 1 148 ? 63.868 -1.659 -7.103 1.00 25.93 ? 148 LYS A NZ 1 ATOM 1148 N N . PRO A 1 149 ? 65.491 1.412 -12.335 1.00 12.91 ? 149 PRO A N 1 ATOM 1149 C CA . PRO A 1 149 ? 64.861 2.667 -12.757 1.00 13.26 ? 149 PRO A CA 1 ATOM 1150 C C . PRO A 1 149 ? 64.151 3.519 -11.709 1.00 13.95 ? 149 PRO A C 1 ATOM 1151 O O . PRO A 1 149 ? 63.752 3.038 -10.648 1.00 14.04 ? 149 PRO A O 1 ATOM 1152 C CB . PRO A 1 149 ? 63.902 2.209 -13.848 1.00 12.66 ? 149 PRO A CB 1 ATOM 1153 C CG . PRO A 1 149 ? 63.447 0.891 -13.329 1.00 14.28 ? 149 PRO A CG 1 ATOM 1154 C CD . PRO A 1 149 ? 64.742 0.253 -12.857 1.00 12.87 ? 149 PRO A CD 1 ATOM 1155 N N . ASN A 1 150 ? 64.009 4.798 -12.039 1.00 16.62 ? 150 ASN A N 1 ATOM 1156 C CA . ASN A 1 150 ? 63.312 5.759 -11.194 1.00 17.35 ? 150 ASN A CA 1 ATOM 1157 C C . ASN A 1 150 ? 61.845 5.422 -11.364 1.00 16.50 ? 150 ASN A C 1 ATOM 1158 O O . ASN A 1 150 ? 61.460 4.812 -12.362 1.00 15.17 ? 150 ASN A O 1 ATOM 1159 C CB . ASN A 1 150 ? 63.503 7.185 -11.716 1.00 19.66 ? 150 ASN A CB 1 ATOM 1160 C CG . ASN A 1 150 ? 64.910 7.702 -11.537 1.00 21.16 ? 150 ASN A CG 1 ATOM 1161 O OD1 . ASN A 1 150 ? 65.363 8.557 -12.300 1.00 24.08 ? 150 ASN A OD1 1 ATOM 1162 N ND2 . ASN A 1 150 ? 65.602 7.212 -10.518 1.00 21.87 ? 150 ASN A ND2 1 ATOM 1163 N N . SER A 1 151 ? 61.019 5.817 -10.406 1.00 16.20 ? 151 SER A N 1 ATOM 1164 C CA . SER A 1 151 ? 59.595 5.577 -10.549 1.00 15.69 ? 151 SER A CA 1 ATOM 1165 C C . SER A 1 151 ? 59.150 6.612 -11.584 1.00 13.65 ? 151 SER A C 1 ATOM 1166 O O . SER A 1 151 ? 59.707 7.709 -11.650 1.00 13.20 ? 151 SER A O 1 ATOM 1167 C CB . SER A 1 151 ? 58.873 5.808 -9.219 1.00 16.99 ? 151 SER A CB 1 ATOM 1168 O OG . SER A 1 151 ? 59.000 7.152 -8.795 1.00 20.51 ? 151 SER A OG 1 ATOM 1169 N N . GLN A 1 152 ? 58.176 6.253 -12.413 1.00 12.43 ? 152 GLN A N 1 ATOM 1170 C CA . GLN A 1 152 ? 57.665 7.162 -13.434 1.00 10.94 ? 152 GLN A CA 1 ATOM 1171 C C . GLN A 1 152 ? 56.153 7.038 -13.462 1.00 11.76 ? 152 GLN A C 1 ATOM 1172 O O . GLN A 1 152 ? 55.619 5.934 -13.565 1.00 11.02 ? 152 GLN A O 1 ATOM 1173 C CB . GLN A 1 152 ? 58.222 6.802 -14.809 1.00 9.68 ? 152 GLN A CB 1 ATOM 1174 C CG . GLN A 1 152 ? 59.736 6.796 -14.898 1.00 11.43 ? 152 GLN A CG 1 ATOM 1175 C CD . GLN A 1 152 ? 60.212 6.302 -16.245 1.00 11.68 ? 152 GLN A CD 1 ATOM 1176 O OE1 . GLN A 1 152 ? 60.464 7.087 -17.161 1.00 10.88 ? 152 GLN A OE1 1 ATOM 1177 N NE2 . GLN A 1 152 ? 60.314 4.985 -16.382 1.00 12.44 ? 152 GLN A NE2 1 ATOM 1178 N N . SER A 1 153 ? 55.466 8.173 -13.390 1.00 12.00 ? 153 SER A N 1 ATOM 1179 C CA . SER A 1 153 ? 54.011 8.180 -13.375 1.00 11.22 ? 153 SER A CA 1 ATOM 1180 C C . SER A 1 153 ? 53.327 7.306 -14.420 1.00 10.14 ? 153 SER A C 1 ATOM 1181 O O . SER A 1 153 ? 52.504 6.457 -14.069 1.00 10.78 ? 153 SER A O 1 ATOM 1182 C CB . SER A 1 153 ? 53.483 9.607 -13.501 1.00 12.28 ? 153 SER A CB 1 ATOM 1183 O OG . SER A 1 153 ? 52.068 9.603 -13.470 1.00 12.96 ? 153 SER A OG 1 ATOM 1184 N N . TRP A 1 154 ? 53.646 7.496 -15.699 1.00 10.07 ? 154 TRP A N 1 ATOM 1185 C CA . TRP A 1 154 ? 52.979 6.689 -16.712 1.00 8.54 ? 154 TRP A CA 1 ATOM 1186 C C . TRP A 1 154 ? 53.283 5.201 -16.594 1.00 8.58 ? 154 TRP A C 1 ATOM 1187 O O . TRP A 1 154 ? 52.416 4.368 -16.858 1.00 8.44 ? 154 TRP A O 1 ATOM 1188 C CB . TRP A 1 154 ? 53.304 7.162 -18.127 1.00 9.25 ? 154 TRP A CB 1 ATOM 1189 C CG . TRP A 1 154 ? 52.506 6.392 -19.127 1.00 9.69 ? 154 TRP A CG 1 ATOM 1190 C CD1 . TRP A 1 154 ? 52.962 5.425 -19.976 1.00 10.06 ? 154 TRP A CD1 1 ATOM 1191 C CD2 . TRP A 1 154 ? 51.084 6.427 -19.285 1.00 10.57 ? 154 TRP A CD2 1 ATOM 1192 N NE1 . TRP A 1 154 ? 51.909 4.849 -20.647 1.00 11.80 ? 154 TRP A NE1 1 ATOM 1193 C CE2 . TRP A 1 154 ? 50.744 5.447 -20.241 1.00 10.42 ? 154 TRP A CE2 1 ATOM 1194 C CE3 . TRP A 1 154 ? 50.061 7.192 -18.706 1.00 10.82 ? 154 TRP A CE3 1 ATOM 1195 C CZ2 . TRP A 1 154 ? 49.422 5.209 -20.635 1.00 10.29 ? 154 TRP A CZ2 1 ATOM 1196 C CZ3 . TRP A 1 154 ? 48.747 6.956 -19.096 1.00 11.73 ? 154 TRP A CZ3 1 ATOM 1197 C CH2 . TRP A 1 154 ? 48.441 5.971 -20.053 1.00 12.52 ? 154 TRP A CH2 1 ATOM 1198 N N . GLN A 1 155 ? 54.506 4.858 -16.206 1.00 8.91 ? 155 GLN A N 1 ATOM 1199 C CA . GLN A 1 155 ? 54.841 3.448 -16.058 1.00 9.46 ? 155 GLN A CA 1 ATOM 1200 C C . GLN A 1 155 ? 54.050 2.870 -14.888 1.00 10.10 ? 155 GLN A C 1 ATOM 1201 O O . GLN A 1 155 ? 53.630 1.712 -14.924 1.00 9.55 ? 155 GLN A O 1 ATOM 1202 C CB . GLN A 1 155 ? 56.347 3.263 -15.841 1.00 8.37 ? 155 GLN A CB 1 ATOM 1203 C CG . GLN A 1 155 ? 57.191 3.612 -17.069 1.00 8.05 ? 155 GLN A CG 1 ATOM 1204 C CD . GLN A 1 155 ? 56.835 2.773 -18.286 1.00 8.76 ? 155 GLN A CD 1 ATOM 1205 O OE1 . GLN A 1 155 ? 56.953 1.547 -18.264 1.00 8.81 ? 155 GLN A OE1 1 ATOM 1206 N NE2 . GLN A 1 155 ? 56.398 3.431 -19.355 1.00 8.42 ? 155 GLN A NE2 1 ATOM 1207 N N . SER A 1 156 ? 53.835 3.680 -13.856 1.00 10.37 ? 156 SER A N 1 ATOM 1208 C CA . SER A 1 156 ? 53.068 3.230 -12.702 1.00 10.48 ? 156 SER A CA 1 ATOM 1209 C C . SER A 1 156 ? 51.608 3.033 -13.098 1.00 10.43 ? 156 SER A C 1 ATOM 1210 O O . SER A 1 156 ? 50.957 2.098 -12.636 1.00 10.54 ? 156 SER A O 1 ATOM 1211 C CB . SER A 1 156 ? 53.173 4.240 -11.556 1.00 10.64 ? 156 SER A CB 1 ATOM 1212 O OG . SER A 1 156 ? 54.488 4.265 -11.028 1.00 12.61 ? 156 SER A OG 1 ATOM 1213 N N . VAL A 1 157 ? 51.086 3.913 -13.949 1.00 9.24 ? 157 VAL A N 1 ATOM 1214 C CA . VAL A 1 157 ? 49.706 3.767 -14.399 1.00 10.49 ? 157 VAL A CA 1 ATOM 1215 C C . VAL A 1 157 ? 49.592 2.448 -15.155 1.00 9.55 ? 157 VAL A C 1 ATOM 1216 O O . VAL A 1 157 ? 48.645 1.687 -14.962 1.00 10.92 ? 157 VAL A O 1 ATOM 1217 C CB . VAL A 1 157 ? 49.282 4.923 -15.334 1.00 11.47 ? 157 VAL A CB 1 ATOM 1218 C CG1 . VAL A 1 157 ? 47.930 4.619 -15.965 1.00 14.51 ? 157 VAL A CG1 1 ATOM 1219 C CG2 . VAL A 1 157 ? 49.206 6.218 -14.545 1.00 12.42 ? 157 VAL A CG2 1 ATOM 1220 N N . THR A 1 158 ? 50.577 2.179 -16.009 1.00 8.94 ? 158 THR A N 1 ATOM 1221 C CA . THR A 1 158 ? 50.605 0.953 -16.796 1.00 8.12 ? 158 THR A CA 1 ATOM 1222 C C . THR A 1 158 ? 50.668 -0.267 -15.879 1.00 8.25 ? 158 THR A C 1 ATOM 1223 O O . THR A 1 158 ? 50.004 -1.275 -16.126 1.00 7.86 ? 158 THR A O 1 ATOM 1224 C CB . THR A 1 158 ? 51.815 0.957 -17.761 1.00 9.47 ? 158 THR A CB 1 ATOM 1225 O OG1 . THR A 1 158 ? 51.705 2.081 -18.644 1.00 9.27 ? 158 THR A OG1 1 ATOM 1226 C CG2 . THR A 1 158 ? 51.850 -0.317 -18.594 1.00 10.65 ? 158 THR A CG2 1 ATOM 1227 N N . LYS A 1 159 ? 51.464 -0.177 -14.819 1.00 8.11 ? 159 LYS A N 1 ATOM 1228 C CA . LYS A 1 159 ? 51.576 -1.280 -13.870 1.00 8.15 ? 159 LYS A CA 1 ATOM 1229 C C . LYS A 1 159 ? 50.212 -1.564 -13.235 1.00 8.03 ? 159 LYS A C 1 ATOM 1230 O O . LYS A 1 159 ? 49.827 -2.724 -13.075 1.00 7.48 ? 159 LYS A O 1 ATOM 1231 C CB . LYS A 1 159 ? 52.612 -0.940 -12.794 1.00 8.99 ? 159 LYS A CB 1 ATOM 1232 C CG . LYS A 1 159 ? 52.715 -1.938 -11.644 1.00 9.23 ? 159 LYS A CG 1 ATOM 1233 C CD . LYS A 1 159 ? 53.947 -1.639 -10.788 1.00 8.44 ? 159 LYS A CD 1 ATOM 1234 C CE . LYS A 1 159 ? 53.956 -2.450 -9.499 1.00 9.97 ? 159 LYS A CE 1 ATOM 1235 N NZ . LYS A 1 159 ? 55.236 -2.253 -8.754 1.00 10.24 ? 159 LYS A NZ 1 ATOM 1236 N N . THR A 1 160 ? 49.473 -0.512 -12.884 1.00 7.74 ? 160 THR A N 1 ATOM 1237 C CA . THR A 1 160 ? 48.158 -0.711 -12.274 1.00 8.12 ? 160 THR A CA 1 ATOM 1238 C C . THR A 1 160 ? 47.192 -1.340 -13.274 1.00 7.99 ? 160 THR A C 1 ATOM 1239 O O . THR A 1 160 ? 46.336 -2.145 -12.901 1.00 8.99 ? 160 THR A O 1 ATOM 1240 C CB . THR A 1 160 ? 47.540 0.619 -11.741 1.00 10.64 ? 160 THR A CB 1 ATOM 1241 O OG1 . THR A 1 160 ? 47.250 1.504 -12.830 1.00 13.97 ? 160 THR A OG1 1 ATOM 1242 C CG2 . THR A 1 160 ? 48.497 1.302 -10.783 1.00 10.21 ? 160 THR A CG2 1 ATOM 1243 N N . ALA A 1 161 ? 47.336 -0.982 -14.547 1.00 7.57 ? 161 ALA A N 1 ATOM 1244 C CA . ALA A 1 161 ? 46.467 -1.530 -15.580 1.00 7.63 ? 161 ALA A CA 1 ATOM 1245 C C . ALA A 1 161 ? 46.735 -3.025 -15.757 1.00 7.50 ? 161 ALA A C 1 ATOM 1246 O O . ALA A 1 161 ? 45.801 -3.818 -15.837 1.00 7.07 ? 161 ALA A O 1 ATOM 1247 C CB . ALA A 1 161 ? 46.685 -0.793 -16.895 1.00 8.87 ? 161 ALA A CB 1 ATOM 1248 N N . PHE A 1 162 ? 48.009 -3.407 -15.822 1.00 7.90 ? 162 PHE A N 1 ATOM 1249 C CA . PHE A 1 162 ? 48.370 -4.817 -15.976 1.00 7.38 ? 162 PHE A CA 1 ATOM 1250 C C . PHE A 1 162 ? 47.835 -5.652 -14.812 1.00 7.65 ? 162 PHE A C 1 ATOM 1251 O O . PHE A 1 162 ? 47.275 -6.730 -15.014 1.00 8.73 ? 162 PHE A O 1 ATOM 1252 C CB . PHE A 1 162 ? 49.895 -4.983 -16.055 1.00 7.47 ? 162 PHE A CB 1 ATOM 1253 C CG . PHE A 1 162 ? 50.473 -4.753 -17.430 1.00 7.86 ? 162 PHE A CG 1 ATOM 1254 C CD1 . PHE A 1 162 ? 51.575 -3.922 -17.601 1.00 9.22 ? 162 PHE A CD1 1 ATOM 1255 C CD2 . PHE A 1 162 ? 49.931 -5.384 -18.551 1.00 10.08 ? 162 PHE A CD2 1 ATOM 1256 C CE1 . PHE A 1 162 ? 52.137 -3.717 -18.866 1.00 8.28 ? 162 PHE A CE1 1 ATOM 1257 C CE2 . PHE A 1 162 ? 50.487 -5.185 -19.822 1.00 9.43 ? 162 PHE A CE2 1 ATOM 1258 C CZ . PHE A 1 162 ? 51.591 -4.351 -19.977 1.00 9.87 ? 162 PHE A CZ 1 ATOM 1259 N N . LEU A 1 163 ? 48.004 -5.154 -13.591 1.00 8.23 ? 163 LEU A N 1 ATOM 1260 C CA . LEU A 1 163 ? 47.534 -5.881 -12.415 1.00 7.65 ? 163 LEU A CA 1 ATOM 1261 C C . LEU A 1 163 ? 46.011 -5.990 -12.377 1.00 9.05 ? 163 LEU A C 1 ATOM 1262 O O . LEU A 1 163 ? 45.464 -7.019 -11.977 1.00 8.85 ? 163 LEU A O 1 ATOM 1263 C CB . LEU A 1 163 ? 48.073 -5.215 -11.140 1.00 9.15 ? 163 LEU A CB 1 ATOM 1264 C CG . LEU A 1 163 ? 49.600 -5.323 -11.012 1.00 8.44 ? 163 LEU A CG 1 ATOM 1265 C CD1 . LEU A 1 163 ? 50.095 -4.480 -9.849 1.00 10.61 ? 163 LEU A CD1 1 ATOM 1266 C CD2 . LEU A 1 163 ? 49.993 -6.786 -10.826 1.00 10.02 ? 163 LEU A CD2 1 ATOM 1267 N N . GLU A 1 164 ? 45.328 -4.936 -12.809 1.00 9.12 ? 164 GLU A N 1 ATOM 1268 C CA . GLU A 1 164 ? 43.876 -4.951 -12.839 1.00 8.92 ? 164 GLU A CA 1 ATOM 1269 C C . GLU A 1 164 ? 43.411 -5.938 -13.913 1.00 9.89 ? 164 GLU A C 1 ATOM 1270 O O . GLU A 1 164 ? 42.382 -6.600 -13.760 1.00 9.57 ? 164 GLU A O 1 ATOM 1271 C CB . GLU A 1 164 ? 43.342 -3.548 -13.148 1.00 11.14 ? 164 GLU A CB 1 ATOM 1272 C CG . GLU A 1 164 ? 41.955 -3.287 -12.598 1.00 14.09 ? 164 GLU A CG 1 ATOM 1273 C CD . GLU A 1 164 ? 41.417 -1.920 -12.972 1.00 10.64 ? 164 GLU A CD 1 ATOM 1274 O OE1 . GLU A 1 164 ? 42.157 -0.924 -12.831 1.00 12.09 ? 164 GLU A OE1 1 ATOM 1275 O OE2 . GLU A 1 164 ? 40.248 -1.845 -13.399 1.00 14.31 ? 164 GLU A OE2 1 ATOM 1276 N N . ALA A 1 165 ? 44.187 -6.046 -14.992 1.00 7.78 ? 165 ALA A N 1 ATOM 1277 C CA . ALA A 1 165 ? 43.848 -6.938 -16.098 1.00 8.65 ? 165 ALA A CA 1 ATOM 1278 C C . ALA A 1 165 ? 44.308 -8.388 -15.928 1.00 9.77 ? 165 ALA A C 1 ATOM 1279 O O . ALA A 1 165 ? 44.344 -9.151 -16.894 1.00 10.27 ? 165 ALA A O 1 ATOM 1280 C CB . ALA A 1 165 ? 44.386 -6.369 -17.406 1.00 6.59 ? 165 ALA A CB 1 ATOM 1281 N N . GLY A 1 166 ? 44.681 -8.760 -14.707 1.00 8.31 ? 166 GLY A N 1 ATOM 1282 C CA . GLY A 1 166 ? 45.081 -10.132 -14.445 1.00 8.55 ? 166 GLY A CA 1 ATOM 1283 C C . GLY A 1 166 ? 46.452 -10.624 -14.871 1.00 9.60 ? 166 GLY A C 1 ATOM 1284 O O . GLY A 1 166 ? 46.680 -11.835 -14.913 1.00 10.82 ? 166 GLY A O 1 ATOM 1285 N N . VAL A 1 167 ? 47.371 -9.723 -15.194 1.00 8.40 ? 167 VAL A N 1 ATOM 1286 C CA . VAL A 1 167 ? 48.707 -10.170 -15.577 1.00 8.68 ? 167 VAL A CA 1 ATOM 1287 C C . VAL A 1 167 ? 49.421 -10.368 -14.241 1.00 9.12 ? 167 VAL A C 1 ATOM 1288 O O . VAL A 1 167 ? 50.099 -9.476 -13.729 1.00 8.94 ? 167 VAL A O 1 ATOM 1289 C CB . VAL A 1 167 ? 49.420 -9.125 -16.448 1.00 9.81 ? 167 VAL A CB 1 ATOM 1290 C CG1 . VAL A 1 167 ? 50.763 -9.674 -16.914 1.00 10.16 ? 167 VAL A CG1 1 ATOM 1291 C CG2 . VAL A 1 167 ? 48.548 -8.787 -17.659 1.00 11.95 ? 167 VAL A CG2 1 ATOM 1292 N N . HIS A 1 168 ? 49.232 -11.562 -13.686 1.00 9.27 ? 168 HIS A N 1 ATOM 1293 C CA . HIS A 1 168 ? 49.760 -11.931 -12.379 1.00 10.17 ? 168 HIS A CA 1 ATOM 1294 C C . HIS A 1 168 ? 50.820 -13.028 -12.417 1.00 9.52 ? 168 HIS A C 1 ATOM 1295 O O . HIS A 1 168 ? 50.907 -13.793 -13.377 1.00 8.72 ? 168 HIS A O 1 ATOM 1296 C CB . HIS A 1 168 ? 48.586 -12.372 -11.501 1.00 9.35 ? 168 HIS A CB 1 ATOM 1297 C CG . HIS A 1 168 ? 47.533 -11.319 -11.334 1.00 9.90 ? 168 HIS A CG 1 ATOM 1298 N ND1 . HIS A 1 168 ? 46.244 -11.607 -10.943 1.00 9.52 ? 168 HIS A ND1 1 ATOM 1299 C CD2 . HIS A 1 168 ? 47.592 -9.973 -11.483 1.00 9.79 ? 168 HIS A CD2 1 ATOM 1300 C CE1 . HIS A 1 168 ? 45.553 -10.483 -10.856 1.00 9.24 ? 168 HIS A CE1 1 ATOM 1301 N NE2 . HIS A 1 168 ? 46.347 -9.478 -11.177 1.00 8.53 ? 168 HIS A NE2 1 ATOM 1302 N N . PRO A 1 169 ? 51.640 -13.121 -11.358 1.00 10.31 ? 169 PRO A N 1 ATOM 1303 C CA . PRO A 1 169 ? 51.623 -12.272 -10.160 1.00 10.13 ? 169 PRO A CA 1 ATOM 1304 C C . PRO A 1 169 ? 52.454 -11.005 -10.337 1.00 10.62 ? 169 PRO A C 1 ATOM 1305 O O . PRO A 1 169 ? 52.960 -10.729 -11.424 1.00 10.13 ? 169 PRO A O 1 ATOM 1306 C CB . PRO A 1 169 ? 52.223 -13.183 -9.100 1.00 10.71 ? 169 PRO A CB 1 ATOM 1307 C CG . PRO A 1 169 ? 53.285 -13.899 -9.887 1.00 9.96 ? 169 PRO A CG 1 ATOM 1308 C CD . PRO A 1 169 ? 52.555 -14.262 -11.172 1.00 9.93 ? 169 PRO A CD 1 ATOM 1309 N N . ASN A 1 170 ? 52.584 -10.236 -9.260 1.00 9.07 ? 170 ASN A N 1 ATOM 1310 C CA . ASN A 1 170 ? 53.397 -9.023 -9.276 1.00 9.41 ? 170 ASN A CA 1 ATOM 1311 C C . ASN A 1 170 ? 54.762 -9.438 -8.738 1.00 11.78 ? 170 ASN A C 1 ATOM 1312 O O . ASN A 1 170 ? 54.849 -10.057 -7.679 1.00 13.16 ? 170 ASN A O 1 ATOM 1313 C CB . ASN A 1 170 ? 52.783 -7.946 -8.376 1.00 8.94 ? 170 ASN A CB 1 ATOM 1314 C CG . ASN A 1 170 ? 53.668 -6.720 -8.240 1.00 9.69 ? 170 ASN A CG 1 ATOM 1315 O OD1 . ASN A 1 170 ? 54.494 -6.433 -9.108 1.00 10.85 ? 170 ASN A OD1 1 ATOM 1316 N ND2 . ASN A 1 170 ? 53.487 -5.980 -7.154 1.00 9.43 ? 170 ASN A ND2 1 ATOM 1317 N N . HIS A 1 171 ? 55.821 -9.113 -9.472 1.00 10.34 ? 171 HIS A N 1 ATOM 1318 C CA . HIS A 1 171 ? 57.175 -9.481 -9.060 1.00 10.23 ? 171 HIS A CA 1 ATOM 1319 C C . HIS A 1 171 ? 57.959 -8.326 -8.444 1.00 10.66 ? 171 HIS A C 1 ATOM 1320 O O . HIS A 1 171 ? 59.113 -8.505 -8.057 1.00 12.47 ? 171 HIS A O 1 ATOM 1321 C CB . HIS A 1 171 ? 57.958 -10.014 -10.264 1.00 9.65 ? 171 HIS A CB 1 ATOM 1322 C CG . HIS A 1 171 ? 57.399 -11.275 -10.842 1.00 10.15 ? 171 HIS A CG 1 ATOM 1323 N ND1 . HIS A 1 171 ? 57.606 -12.512 -10.271 1.00 11.52 ? 171 HIS A ND1 1 ATOM 1324 C CD2 . HIS A 1 171 ? 56.625 -11.488 -11.932 1.00 11.24 ? 171 HIS A CD2 1 ATOM 1325 C CE1 . HIS A 1 171 ? 56.984 -13.433 -10.985 1.00 11.51 ? 171 HIS A CE1 1 ATOM 1326 N NE2 . HIS A 1 171 ? 56.380 -12.837 -11.998 1.00 12.43 ? 171 HIS A NE2 1 ATOM 1327 N N . GLY A 1 172 ? 57.339 -7.152 -8.347 1.00 9.99 ? 172 GLY A N 1 ATOM 1328 C CA . GLY A 1 172 ? 58.035 -5.996 -7.804 1.00 10.34 ? 172 GLY A CA 1 ATOM 1329 C C . GLY A 1 172 ? 59.128 -5.619 -8.784 1.00 10.56 ? 172 GLY A C 1 ATOM 1330 O O . GLY A 1 172 ? 58.872 -5.552 -9.986 1.00 10.67 ? 172 GLY A O 1 ATOM 1331 N N . PHE A 1 173 ? 60.334 -5.348 -8.291 1.00 9.46 ? 173 PHE A N 1 ATOM 1332 C CA . PHE A 1 173 ? 61.449 -5.041 -9.184 1.00 10.70 ? 173 PHE A CA 1 ATOM 1333 C C . PHE A 1 173 ? 62.220 -6.338 -9.373 1.00 10.58 ? 173 PHE A C 1 ATOM 1334 O O . PHE A 1 173 ? 62.707 -6.923 -8.400 1.00 11.31 ? 173 PHE A O 1 ATOM 1335 C CB . PHE A 1 173 ? 62.399 -3.998 -8.592 1.00 10.91 ? 173 PHE A CB 1 ATOM 1336 C CG . PHE A 1 173 ? 63.678 -3.842 -9.379 1.00 10.31 ? 173 PHE A CG 1 ATOM 1337 C CD1 . PHE A 1 173 ? 63.656 -3.323 -10.671 1.00 12.96 ? 173 PHE A CD1 1 ATOM 1338 C CD2 . PHE A 1 173 ? 64.896 -4.253 -8.845 1.00 12.28 ? 173 PHE A CD2 1 ATOM 1339 C CE1 . PHE A 1 173 ? 64.830 -3.217 -11.424 1.00 13.25 ? 173 PHE A CE1 1 ATOM 1340 C CE2 . PHE A 1 173 ? 66.077 -4.153 -9.586 1.00 12.47 ? 173 PHE A CE2 1 ATOM 1341 C CZ . PHE A 1 173 ? 66.043 -3.633 -10.880 1.00 12.79 ? 173 PHE A CZ 1 ATOM 1342 N N . SER A 1 174 ? 62.337 -6.787 -10.617 1.00 8.75 ? 174 SER A N 1 ATOM 1343 C CA . SER A 1 174 ? 63.045 -8.029 -10.906 1.00 8.47 ? 174 SER A CA 1 ATOM 1344 C C . SER A 1 174 ? 63.542 -8.043 -12.343 1.00 9.29 ? 174 SER A C 1 ATOM 1345 O O . SER A 1 174 ? 62.850 -7.582 -13.249 1.00 10.75 ? 174 SER A O 1 ATOM 1346 C CB . SER A 1 174 ? 62.120 -9.226 -10.670 1.00 10.95 ? 174 SER A CB 1 ATOM 1347 O OG . SER A 1 174 ? 62.763 -10.444 -11.006 1.00 11.08 ? 174 SER A OG 1 ATOM 1348 N N . LEU A 1 175 ? 64.740 -8.584 -12.546 1.00 9.99 ? 175 LEU A N 1 ATOM 1349 C CA . LEU A 1 175 ? 65.342 -8.651 -13.875 1.00 9.54 ? 175 LEU A CA 1 ATOM 1350 C C . LEU A 1 175 ? 64.915 -9.878 -14.669 1.00 9.79 ? 175 LEU A C 1 ATOM 1351 O O . LEU A 1 175 ? 65.083 -9.926 -15.889 1.00 9.98 ? 175 LEU A O 1 ATOM 1352 C CB . LEU A 1 175 ? 66.866 -8.671 -13.755 1.00 9.72 ? 175 LEU A CB 1 ATOM 1353 C CG . LEU A 1 175 ? 67.515 -7.519 -12.993 1.00 10.27 ? 175 LEU A CG 1 ATOM 1354 C CD1 . LEU A 1 175 ? 69.015 -7.735 -12.928 1.00 12.40 ? 175 LEU A CD1 1 ATOM 1355 C CD2 . LEU A 1 175 ? 67.182 -6.210 -13.686 1.00 9.76 ? 175 LEU A CD2 1 ATOM 1356 N N . ASP A 1 176 ? 64.361 -10.864 -13.976 1.00 9.32 ? 176 ASP A N 1 ATOM 1357 C CA . ASP A 1 176 ? 63.965 -12.113 -14.611 1.00 8.94 ? 176 ASP A CA 1 ATOM 1358 C C . ASP A 1 176 ? 62.676 -12.142 -15.418 1.00 9.05 ? 176 ASP A C 1 ATOM 1359 O O . ASP A 1 176 ? 61.640 -11.621 -15.001 1.00 9.63 ? 176 ASP A O 1 ATOM 1360 C CB . ASP A 1 176 ? 63.920 -13.219 -13.562 1.00 9.95 ? 176 ASP A CB 1 ATOM 1361 C CG . ASP A 1 176 ? 65.291 -13.564 -13.033 1.00 11.61 ? 176 ASP A CG 1 ATOM 1362 O OD1 . ASP A 1 176 ? 66.128 -14.036 -13.829 1.00 12.12 ? 176 ASP A OD1 1 ATOM 1363 O OD2 . ASP A 1 176 ? 65.532 -13.360 -11.827 1.00 13.53 ? 176 ASP A OD2 1 ATOM 1364 N N . HIS A 1 177 ? 62.767 -12.782 -16.578 1.00 8.72 ? 177 HIS A N 1 ATOM 1365 C CA . HIS A 1 177 ? 61.638 -12.943 -17.481 1.00 8.95 ? 177 HIS A CA 1 ATOM 1366 C C . HIS A 1 177 ? 60.709 -14.009 -16.906 1.00 9.23 ? 177 HIS A C 1 ATOM 1367 O O . HIS A 1 177 ? 60.956 -15.208 -17.062 1.00 11.59 ? 177 HIS A O 1 ATOM 1368 C CB . HIS A 1 177 ? 62.130 -13.392 -18.857 1.00 8.26 ? 177 HIS A CB 1 ATOM 1369 C CG . HIS A 1 177 ? 61.029 -13.636 -19.838 1.00 7.59 ? 177 HIS A CG 1 ATOM 1370 N ND1 . HIS A 1 177 ? 60.511 -12.640 -20.640 1.00 8.02 ? 177 HIS A ND1 1 ATOM 1371 C CD2 . HIS A 1 177 ? 60.317 -14.753 -20.119 1.00 10.03 ? 177 HIS A CD2 1 ATOM 1372 C CE1 . HIS A 1 177 ? 59.529 -13.135 -21.372 1.00 8.18 ? 177 HIS A CE1 1 ATOM 1373 N NE2 . HIS A 1 177 ? 59.390 -14.415 -21.074 1.00 9.45 ? 177 HIS A NE2 1 ATOM 1374 N N . GLU A 1 178 ? 59.652 -13.570 -16.234 1.00 8.78 ? 178 GLU A N 1 ATOM 1375 C CA . GLU A 1 178 ? 58.685 -14.481 -15.637 1.00 9.67 ? 178 GLU A CA 1 ATOM 1376 C C . GLU A 1 178 ? 57.270 -13.993 -15.892 1.00 8.48 ? 178 GLU A C 1 ATOM 1377 O O . GLU A 1 178 ? 57.023 -12.790 -15.987 1.00 9.84 ? 178 GLU A O 1 ATOM 1378 C CB . GLU A 1 178 ? 58.885 -14.574 -14.127 1.00 12.25 ? 178 GLU A CB 1 ATOM 1379 C CG . GLU A 1 178 ? 60.259 -15.004 -13.671 1.00 14.51 ? 178 GLU A CG 1 ATOM 1380 C CD . GLU A 1 178 ? 60.319 -15.148 -12.163 1.00 16.76 ? 178 GLU A CD 1 ATOM 1381 O OE1 . GLU A 1 178 ? 59.834 -16.176 -11.643 1.00 19.48 ? 178 GLU A OE1 1 ATOM 1382 O OE2 . GLU A 1 178 ? 60.831 -14.223 -11.497 1.00 16.92 ? 178 GLU A OE2 1 ATOM 1383 N N . GLU A 1 179 ? 56.340 -14.935 -15.987 1.00 9.79 ? 179 GLU A N 1 ATOM 1384 C CA . GLU A 1 179 ? 54.939 -14.602 -16.200 1.00 9.72 ? 179 GLU A CA 1 ATOM 1385 C C . GLU A 1 179 ? 54.489 -13.649 -15.097 1.00 10.12 ? 179 GLU A C 1 ATOM 1386 O O . GLU A 1 179 ? 54.816 -13.848 -13.925 1.00 10.21 ? 179 GLU A O 1 ATOM 1387 C CB . GLU A 1 179 ? 54.095 -15.876 -16.164 1.00 12.44 ? 179 GLU A CB 1 ATOM 1388 C CG . GLU A 1 179 ? 52.611 -15.650 -16.380 1.00 17.58 ? 179 GLU A CG 1 ATOM 1389 C CD . GLU A 1 179 ? 51.834 -16.951 -16.405 1.00 20.98 ? 179 GLU A CD 1 ATOM 1390 O OE1 . GLU A 1 179 ? 52.450 -18.011 -16.168 1.00 24.13 ? 179 GLU A OE1 1 ATOM 1391 O OE2 . GLU A 1 179 ? 50.612 -16.914 -16.658 1.00 22.88 ? 179 GLU A OE2 1 ATOM 1392 N N . GLY A 1 180 ? 53.741 -12.615 -15.477 1.00 8.55 ? 180 GLY A N 1 ATOM 1393 C CA . GLY A 1 180 ? 53.263 -11.645 -14.509 1.00 8.70 ? 180 GLY A CA 1 ATOM 1394 C C . GLY A 1 180 ? 53.756 -10.239 -14.807 1.00 6.81 ? 180 GLY A C 1 ATOM 1395 O O . GLY A 1 180 ? 54.358 -9.988 -15.855 1.00 7.49 ? 180 GLY A O 1 ATOM 1396 N N . THR A 1 181 ? 53.505 -9.327 -13.875 1.00 6.31 ? 181 THR A N 1 ATOM 1397 C CA . THR A 1 181 ? 53.898 -7.929 -14.014 1.00 7.14 ? 181 THR A CA 1 ATOM 1398 C C . THR A 1 181 ? 55.088 -7.585 -13.129 1.00 7.94 ? 181 THR A C 1 ATOM 1399 O O . THR A 1 181 ? 55.175 -8.041 -11.992 1.00 8.17 ? 181 THR A O 1 ATOM 1400 C CB . THR A 1 181 ? 52.733 -7.004 -13.628 1.00 8.68 ? 181 THR A CB 1 ATOM 1401 O OG1 . THR A 1 181 ? 51.615 -7.272 -14.481 1.00 7.88 ? 181 THR A OG1 1 ATOM 1402 C CG2 . THR A 1 181 ? 53.134 -5.545 -13.757 1.00 8.87 ? 181 THR A CG2 1 ATOM 1403 N N . ARG A 1 182 ? 55.995 -6.766 -13.649 1.00 8.01 ? 182 ARG A N 1 ATOM 1404 C CA . ARG A 1 182 ? 57.166 -6.362 -12.882 1.00 6.71 ? 182 ARG A CA 1 ATOM 1405 C C . ARG A 1 182 ? 57.794 -5.101 -13.453 1.00 7.47 ? 182 ARG A C 1 ATOM 1406 O O . ARG A 1 182 ? 57.444 -4.654 -14.545 1.00 8.05 ? 182 ARG A O 1 ATOM 1407 C CB . ARG A 1 182 ? 58.227 -7.469 -12.900 1.00 6.21 ? 182 ARG A CB 1 ATOM 1408 C CG . ARG A 1 182 ? 59.082 -7.514 -14.178 1.00 8.88 ? 182 ARG A CG 1 ATOM 1409 C CD . ARG A 1 182 ? 60.058 -8.686 -14.135 1.00 6.35 ? 182 ARG A CD 1 ATOM 1410 N NE . ARG A 1 182 ? 61.099 -8.621 -15.161 1.00 6.91 ? 182 ARG A NE 1 ATOM 1411 C CZ . ARG A 1 182 ? 60.951 -9.009 -16.426 1.00 7.17 ? 182 ARG A CZ 1 ATOM 1412 N NH1 . ARG A 1 182 ? 59.791 -9.496 -16.851 1.00 9.11 ? 182 ARG A NH1 1 ATOM 1413 N NH2 . ARG A 1 182 ? 61.980 -8.931 -17.264 1.00 8.77 ? 182 ARG A NH2 1 ATOM 1414 N N . ILE A 1 183 ? 58.710 -4.527 -12.680 1.00 7.35 ? 183 ILE A N 1 ATOM 1415 C CA . ILE A 1 183 ? 59.484 -3.375 -13.115 1.00 8.30 ? 183 ILE A CA 1 ATOM 1416 C C . ILE A 1 183 ? 60.835 -4.041 -13.328 1.00 8.88 ? 183 ILE A C 1 ATOM 1417 O O . ILE A 1 183 ? 61.363 -4.679 -12.417 1.00 9.63 ? 183 ILE A O 1 ATOM 1418 C CB . ILE A 1 183 ? 59.621 -2.301 -12.016 1.00 9.91 ? 183 ILE A CB 1 ATOM 1419 C CG1 . ILE A 1 183 ? 58.254 -1.676 -11.732 1.00 11.39 ? 183 ILE A CG1 1 ATOM 1420 C CG2 . ILE A 1 183 ? 60.615 -1.222 -12.459 1.00 11.16 ? 183 ILE A CG2 1 ATOM 1421 C CD1 . ILE A 1 183 ? 58.280 -0.621 -10.643 1.00 14.44 ? 183 ILE A CD1 1 ATOM 1422 N N . THR A 1 184 ? 61.381 -3.927 -14.532 1.00 8.98 ? 184 THR A N 1 ATOM 1423 C CA . THR A 1 184 ? 62.658 -4.559 -14.821 1.00 8.76 ? 184 THR A CA 1 ATOM 1424 C C . THR A 1 184 ? 63.784 -3.526 -14.874 1.00 8.26 ? 184 THR A C 1 ATOM 1425 O O . THR A 1 184 ? 63.567 -2.350 -14.587 1.00 9.52 ? 184 THR A O 1 ATOM 1426 C CB . THR A 1 184 ? 62.577 -5.354 -16.150 1.00 7.94 ? 184 THR A CB 1 ATOM 1427 O OG1 . THR A 1 184 ? 63.675 -6.268 -16.226 1.00 10.39 ? 184 THR A OG1 1 ATOM 1428 C CG2 . THR A 1 184 ? 62.613 -4.415 -17.354 1.00 9.43 ? 184 THR A CG2 1 ATOM 1429 N N . GLY A 1 185 ? 64.986 -3.967 -15.228 1.00 8.50 ? 185 GLY A N 1 ATOM 1430 C CA . GLY A 1 185 ? 66.106 -3.047 -15.299 1.00 8.74 ? 185 GLY A CA 1 ATOM 1431 C C . GLY A 1 185 ? 66.169 -2.297 -16.616 1.00 8.15 ? 185 GLY A C 1 ATOM 1432 O O . GLY A 1 185 ? 65.448 -2.620 -17.560 1.00 7.79 ? 185 GLY A O 1 ATOM 1433 N N . SER A 1 186 ? 67.026 -1.285 -16.682 1.00 8.87 ? 186 SER A N 1 ATOM 1434 C CA . SER A 1 186 ? 67.182 -0.502 -17.904 1.00 8.90 ? 186 SER A CA 1 ATOM 1435 C C . SER A 1 186 ? 68.644 -0.132 -18.101 1.00 8.32 ? 186 SER A C 1 ATOM 1436 O O . SER A 1 186 ? 69.396 -0.033 -17.130 1.00 7.14 ? 186 SER A O 1 ATOM 1437 C CB . SER A 1 186 ? 66.336 0.775 -17.822 1.00 9.68 ? 186 SER A CB 1 ATOM 1438 O OG . SER A 1 186 ? 66.559 1.621 -18.936 1.00 9.96 ? 186 SER A OG 1 ATOM 1439 N N . THR A 1 187 ? 69.057 0.047 -19.352 1.00 8.33 ? 187 THR A N 1 ATOM 1440 C CA . THR A 1 187 ? 70.429 0.444 -19.615 1.00 8.60 ? 187 THR A CA 1 ATOM 1441 C C . THR A 1 187 ? 70.533 1.972 -19.595 1.00 9.76 ? 187 THR A C 1 ATOM 1442 O O . THR A 1 187 ? 71.594 2.543 -19.847 1.00 8.99 ? 187 THR A O 1 ATOM 1443 C CB . THR A 1 187 ? 70.975 -0.158 -20.943 1.00 8.27 ? 187 THR A CB 1 ATOM 1444 O OG1 . THR A 1 187 ? 69.976 -0.097 -21.968 1.00 7.65 ? 187 THR A OG1 1 ATOM 1445 C CG2 . THR A 1 187 ? 71.384 -1.618 -20.724 1.00 8.54 ? 187 THR A CG2 1 ATOM 1446 N N . PHE A 1 188 ? 69.412 2.628 -19.307 1.00 9.06 ? 188 PHE A N 1 ATOM 1447 C CA . PHE A 1 188 ? 69.393 4.084 -19.156 1.00 8.94 ? 188 PHE A CA 1 ATOM 1448 C C . PHE A 1 188 ? 69.505 4.267 -17.642 1.00 10.20 ? 188 PHE A C 1 ATOM 1449 O O . PHE A 1 188 ? 68.793 3.590 -16.895 1.00 11.05 ? 188 PHE A O 1 ATOM 1450 C CB . PHE A 1 188 ? 68.056 4.691 -19.597 1.00 10.14 ? 188 PHE A CB 1 ATOM 1451 C CG . PHE A 1 188 ? 67.853 4.728 -21.082 1.00 8.19 ? 188 PHE A CG 1 ATOM 1452 C CD1 . PHE A 1 188 ? 66.792 4.040 -21.663 1.00 9.24 ? 188 PHE A CD1 1 ATOM 1453 C CD2 . PHE A 1 188 ? 68.703 5.470 -21.900 1.00 8.77 ? 188 PHE A CD2 1 ATOM 1454 C CE1 . PHE A 1 188 ? 66.579 4.088 -23.041 1.00 9.56 ? 188 PHE A CE1 1 ATOM 1455 C CE2 . PHE A 1 188 ? 68.500 5.523 -23.277 1.00 9.33 ? 188 PHE A CE2 1 ATOM 1456 C CZ . PHE A 1 188 ? 67.434 4.831 -23.849 1.00 8.82 ? 188 PHE A CZ 1 ATOM 1457 N N . ASP A 1 189 ? 70.382 5.151 -17.170 1.00 9.89 ? 189 ASP A N 1 ATOM 1458 C CA . ASP A 1 189 ? 70.472 5.337 -15.728 1.00 10.58 ? 189 ASP A CA 1 ATOM 1459 C C . ASP A 1 189 ? 69.458 6.365 -15.230 1.00 10.71 ? 189 ASP A C 1 ATOM 1460 O O . ASP A 1 189 ? 68.693 6.932 -16.014 1.00 11.37 ? 189 ASP A O 1 ATOM 1461 C CB . ASP A 1 189 ? 71.901 5.695 -15.269 1.00 11.24 ? 189 ASP A CB 1 ATOM 1462 C CG . ASP A 1 189 ? 72.361 7.067 -15.719 1.00 11.95 ? 189 ASP A CG 1 ATOM 1463 O OD1 . ASP A 1 189 ? 71.520 7.958 -15.964 1.00 12.71 ? 189 ASP A OD1 1 ATOM 1464 O OD2 . ASP A 1 189 ? 73.594 7.255 -15.800 1.00 11.12 ? 189 ASP A OD2 1 ATOM 1465 N N . ASN A 1 190 ? 69.459 6.605 -13.926 1.00 12.44 ? 190 ASN A N 1 ATOM 1466 C CA . ASN A 1 190 ? 68.499 7.512 -13.312 1.00 14.25 ? 190 ASN A CA 1 ATOM 1467 C C . ASN A 1 190 ? 68.545 8.979 -13.733 1.00 14.75 ? 190 ASN A C 1 ATOM 1468 O O . ASN A 1 190 ? 67.678 9.765 -13.344 1.00 15.39 ? 190 ASN A O 1 ATOM 1469 C CB . ASN A 1 190 ? 68.598 7.365 -11.796 1.00 16.36 ? 190 ASN A CB 1 ATOM 1470 C CG . ASN A 1 190 ? 68.533 5.911 -11.363 1.00 19.22 ? 190 ASN A CG 1 ATOM 1471 O OD1 . ASN A 1 190 ? 69.450 5.134 -11.630 1.00 22.89 ? 190 ASN A OD1 1 ATOM 1472 N ND2 . ASN A 1 190 ? 67.442 5.529 -10.714 1.00 22.06 ? 190 ASN A ND2 1 ATOM 1473 N N . LYS A 1 191 ? 69.540 9.347 -14.534 1.00 14.42 ? 191 LYS A N 1 ATOM 1474 C CA . LYS A 1 191 ? 69.645 10.717 -15.025 1.00 15.00 ? 191 LYS A CA 1 ATOM 1475 C C . LYS A 1 191 ? 69.312 10.734 -16.512 1.00 14.30 ? 191 LYS A C 1 ATOM 1476 O O . LYS A 1 191 ? 69.380 11.774 -17.165 1.00 16.02 ? 191 LYS A O 1 ATOM 1477 C CB . LYS A 1 191 ? 71.051 11.275 -14.793 1.00 16.90 ? 191 LYS A CB 1 ATOM 1478 C CG . LYS A 1 191 ? 71.369 11.516 -13.326 1.00 21.10 ? 191 LYS A CG 1 ATOM 1479 C CD . LYS A 1 191 ? 72.742 12.142 -13.140 1.00 23.69 ? 191 LYS A CD 1 ATOM 1480 C CE . LYS A 1 191 ? 73.060 12.319 -11.661 1.00 26.08 ? 191 LYS A CE 1 ATOM 1481 N NZ . LYS A 1 191 ? 74.398 12.937 -11.438 1.00 30.55 ? 191 LYS A NZ 1 ATOM 1482 N N . GLY A 1 192 ? 68.950 9.569 -17.040 1.00 13.50 ? 192 GLY A N 1 ATOM 1483 C CA . GLY A 1 192 ? 68.604 9.470 -18.446 1.00 11.90 ? 192 GLY A CA 1 ATOM 1484 C C . GLY A 1 192 ? 69.782 9.211 -19.364 1.00 11.29 ? 192 GLY A C 1 ATOM 1485 O O . GLY A 1 192 ? 69.632 9.206 -20.585 1.00 12.06 ? 192 GLY A O 1 ATOM 1486 N N . THR A 1 193 ? 70.959 8.998 -18.786 1.00 11.43 ? 193 THR A N 1 ATOM 1487 C CA . THR A 1 193 ? 72.151 8.735 -19.585 1.00 10.30 ? 193 THR A CA 1 ATOM 1488 C C . THR A 1 193 ? 72.131 7.303 -20.101 1.00 10.61 ? 193 THR A C 1 ATOM 1489 O O . THR A 1 193 ? 71.921 6.369 -19.333 1.00 10.33 ? 193 THR A O 1 ATOM 1490 C CB . THR A 1 193 ? 73.429 8.927 -18.755 1.00 11.33 ? 193 THR A CB 1 ATOM 1491 O OG1 . THR A 1 193 ? 73.504 10.287 -18.309 1.00 14.93 ? 193 THR A OG1 1 ATOM 1492 C CG2 . THR A 1 193 ? 74.661 8.598 -19.588 1.00 10.73 ? 193 THR A CG2 1 ATOM 1493 N N . ARG A 1 194 ? 72.347 7.128 -21.401 1.00 10.22 ? 194 ARG A N 1 ATOM 1494 C CA . ARG A 1 194 ? 72.359 5.785 -21.959 1.00 9.94 ? 194 ARG A CA 1 ATOM 1495 C C . ARG A 1 194 ? 73.705 5.112 -21.763 1.00 10.35 ? 194 ARG A C 1 ATOM 1496 O O . ARG A 1 194 ? 74.757 5.704 -22.003 1.00 12.13 ? 194 ARG A O 1 ATOM 1497 C CB . ARG A 1 194 ? 72.054 5.781 -23.460 1.00 10.63 ? 194 ARG A CB 1 ATOM 1498 C CG . ARG A 1 194 ? 71.981 4.353 -24.018 1.00 9.61 ? 194 ARG A CG 1 ATOM 1499 C CD . ARG A 1 194 ? 72.113 4.304 -25.528 1.00 9.31 ? 194 ARG A CD 1 ATOM 1500 N NE . ARG A 1 194 ? 70.937 4.799 -26.237 1.00 8.96 ? 194 ARG A NE 1 ATOM 1501 C CZ . ARG A 1 194 ? 69.809 4.113 -26.390 1.00 7.71 ? 194 ARG A CZ 1 ATOM 1502 N NH1 . ARG A 1 194 ? 69.694 2.896 -25.872 1.00 8.86 ? 194 ARG A NH1 1 ATOM 1503 N NH2 . ARG A 1 194 ? 68.807 4.629 -27.088 1.00 9.15 ? 194 ARG A NH2 1 ATOM 1504 N N . HIS A 1 195 ? 73.656 3.867 -21.314 1.00 9.74 ? 195 HIS A N 1 ATOM 1505 C CA . HIS A 1 195 ? 74.849 3.065 -21.136 1.00 8.68 ? 195 HIS A CA 1 ATOM 1506 C C . HIS A 1 195 ? 74.638 1.920 -22.117 1.00 9.83 ? 195 HIS A C 1 ATOM 1507 O O . HIS A 1 195 ? 73.501 1.529 -22.382 1.00 9.93 ? 195 HIS A O 1 ATOM 1508 C CB . HIS A 1 195 ? 74.956 2.604 -19.683 1.00 9.83 ? 195 HIS A CB 1 ATOM 1509 C CG . HIS A 1 195 ? 75.239 3.728 -18.733 1.00 11.05 ? 195 HIS A CG 1 ATOM 1510 N ND1 . HIS A 1 195 ? 76.514 4.201 -18.498 1.00 10.19 ? 195 HIS A ND1 1 ATOM 1511 C CD2 . HIS A 1 195 ? 74.408 4.524 -18.021 1.00 10.97 ? 195 HIS A CD2 1 ATOM 1512 C CE1 . HIS A 1 195 ? 76.453 5.238 -17.682 1.00 13.04 ? 195 HIS A CE1 1 ATOM 1513 N NE2 . HIS A 1 195 ? 75.186 5.455 -17.377 1.00 10.79 ? 195 HIS A NE2 1 ATOM 1514 N N . ALA A 1 196 ? 75.717 1.407 -22.690 1.00 9.39 ? 196 ALA A N 1 ATOM 1515 C CA . ALA A 1 196 ? 75.569 0.355 -23.685 1.00 9.71 ? 196 ALA A CA 1 ATOM 1516 C C . ALA A 1 196 ? 76.752 -0.587 -23.771 1.00 8.46 ? 196 ALA A C 1 ATOM 1517 O O . ALA A 1 196 ? 77.698 -0.495 -22.989 1.00 7.57 ? 196 ALA A O 1 ATOM 1518 C CB . ALA A 1 196 ? 75.308 0.982 -25.050 1.00 8.44 ? 196 ALA A CB 1 ATOM 1519 N N . ALA A 1 197 ? 76.693 -1.484 -24.750 1.00 7.37 ? 197 ALA A N 1 ATOM 1520 C CA . ALA A 1 197 ? 77.737 -2.479 -24.949 1.00 8.01 ? 197 ALA A CA 1 ATOM 1521 C C . ALA A 1 197 ? 79.146 -1.917 -25.132 1.00 7.49 ? 197 ALA A C 1 ATOM 1522 O O . ALA A 1 197 ? 80.121 -2.570 -24.758 1.00 9.04 ? 197 ALA A O 1 ATOM 1523 C CB . ALA A 1 197 ? 77.378 -3.373 -26.134 1.00 8.42 ? 197 ALA A CB 1 ATOM 1524 N N . ASP A 1 198 ? 79.267 -0.720 -25.700 1.00 8.75 ? 198 ASP A N 1 ATOM 1525 C CA . ASP A 1 198 ? 80.587 -0.140 -25.904 1.00 8.81 ? 198 ASP A CA 1 ATOM 1526 C C . ASP A 1 198 ? 81.338 0.024 -24.589 1.00 8.92 ? 198 ASP A C 1 ATOM 1527 O O . ASP A 1 198 ? 82.555 -0.138 -24.540 1.00 8.88 ? 198 ASP A O 1 ATOM 1528 C CB . ASP A 1 198 ? 80.484 1.207 -26.639 1.00 9.38 ? 198 ASP A CB 1 ATOM 1529 C CG . ASP A 1 198 ? 79.728 2.261 -25.849 1.00 10.33 ? 198 ASP A CG 1 ATOM 1530 O OD1 . ASP A 1 198 ? 78.611 1.972 -25.374 1.00 11.10 ? 198 ASP A OD1 1 ATOM 1531 O OD2 . ASP A 1 198 ? 80.247 3.393 -25.722 1.00 10.15 ? 198 ASP A OD2 1 ATOM 1532 N N . GLU A 1 199 ? 80.614 0.322 -23.516 1.00 9.67 ? 199 GLU A N 1 ATOM 1533 C CA . GLU A 1 199 ? 81.251 0.502 -22.219 1.00 9.43 ? 199 GLU A CA 1 ATOM 1534 C C . GLU A 1 199 ? 81.836 -0.785 -21.660 1.00 10.24 ? 199 GLU A C 1 ATOM 1535 O O . GLU A 1 199 ? 82.684 -0.747 -20.772 1.00 11.68 ? 199 GLU A O 1 ATOM 1536 C CB . GLU A 1 199 ? 80.260 1.086 -21.219 1.00 9.84 ? 199 GLU A CB 1 ATOM 1537 C CG . GLU A 1 199 ? 79.995 2.560 -21.430 1.00 9.35 ? 199 GLU A CG 1 ATOM 1538 C CD . GLU A 1 199 ? 78.835 3.045 -20.606 1.00 11.89 ? 199 GLU A CD 1 ATOM 1539 O OE1 . GLU A 1 199 ? 77.685 2.736 -20.977 1.00 12.63 ? 199 GLU A OE1 1 ATOM 1540 O OE2 . GLU A 1 199 ? 79.070 3.721 -19.583 1.00 11.54 ? 199 GLU A OE2 1 ATOM 1541 N N . LEU A 1 200 ? 81.382 -1.926 -22.167 1.00 9.64 ? 200 LEU A N 1 ATOM 1542 C CA . LEU A 1 200 ? 81.911 -3.193 -21.687 1.00 9.52 ? 200 LEU A CA 1 ATOM 1543 C C . LEU A 1 200 ? 83.342 -3.371 -22.208 1.00 10.67 ? 200 LEU A C 1 ATOM 1544 O O . LEU A 1 200 ? 84.092 -4.224 -21.728 1.00 9.79 ? 200 LEU A O 1 ATOM 1545 C CB . LEU A 1 200 ? 80.997 -4.351 -22.117 1.00 10.46 ? 200 LEU A CB 1 ATOM 1546 C CG . LEU A 1 200 ? 79.593 -4.286 -21.486 1.00 10.12 ? 200 LEU A CG 1 ATOM 1547 C CD1 . LEU A 1 200 ? 78.723 -5.423 -22.011 1.00 11.02 ? 200 LEU A CD1 1 ATOM 1548 C CD2 . LEU A 1 200 ? 79.703 -4.363 -19.967 1.00 10.43 ? 200 LEU A CD2 1 ATOM 1549 N N . LEU A 1 201 ? 83.723 -2.543 -23.178 1.00 9.80 ? 201 LEU A N 1 ATOM 1550 C CA . LEU A 1 201 ? 85.078 -2.583 -23.729 1.00 10.43 ? 201 LEU A CA 1 ATOM 1551 C C . LEU A 1 201 ? 86.053 -2.124 -22.643 1.00 11.72 ? 201 LEU A C 1 ATOM 1552 O O . LEU A 1 201 ? 87.227 -2.493 -22.651 1.00 11.91 ? 201 LEU A O 1 ATOM 1553 C CB . LEU A 1 201 ? 85.197 -1.655 -24.944 1.00 9.87 ? 201 LEU A CB 1 ATOM 1554 C CG . LEU A 1 201 ? 84.409 -2.025 -26.207 1.00 10.15 ? 201 LEU A CG 1 ATOM 1555 C CD1 . LEU A 1 201 ? 84.487 -0.882 -27.210 1.00 10.16 ? 201 LEU A CD1 1 ATOM 1556 C CD2 . LEU A 1 201 ? 84.967 -3.309 -26.815 1.00 9.26 ? 201 LEU A CD2 1 ATOM 1557 N N . ASN A 1 202 ? 85.555 -1.320 -21.706 1.00 11.47 ? 202 ASN A N 1 ATOM 1558 C CA . ASN A 1 202 ? 86.379 -0.807 -20.610 1.00 11.90 ? 202 ASN A CA 1 ATOM 1559 C C . ASN A 1 202 ? 86.814 -1.910 -19.658 1.00 13.40 ? 202 ASN A C 1 ATOM 1560 O O . ASN A 1 202 ? 87.726 -1.721 -18.852 1.00 13.29 ? 202 ASN A O 1 ATOM 1561 C CB . ASN A 1 202 ? 85.618 0.264 -19.820 1.00 11.84 ? 202 ASN A CB 1 ATOM 1562 C CG . ASN A 1 202 ? 85.367 1.515 -20.632 1.00 11.69 ? 202 ASN A CG 1 ATOM 1563 O OD1 . ASN A 1 202 ? 86.285 2.066 -21.239 1.00 13.33 ? 202 ASN A OD1 1 ATOM 1564 N ND2 . ASN A 1 202 ? 84.121 1.979 -20.641 1.00 11.45 ? 202 ASN A ND2 1 ATOM 1565 N N . LYS A 1 203 ? 86.154 -3.059 -19.754 1.00 12.97 ? 203 LYS A N 1 ATOM 1566 C CA . LYS A 1 203 ? 86.464 -4.205 -18.907 1.00 14.61 ? 203 LYS A CA 1 ATOM 1567 C C . LYS A 1 203 ? 87.612 -5.009 -19.510 1.00 13.25 ? 203 LYS A C 1 ATOM 1568 O O . LYS A 1 203 ? 88.130 -5.931 -18.883 1.00 15.12 ? 203 LYS A O 1 ATOM 1569 C CB . LYS A 1 203 ? 85.230 -5.098 -18.766 1.00 15.81 ? 203 LYS A CB 1 ATOM 1570 C CG . LYS A 1 203 ? 83.996 -4.379 -18.236 1.00 19.69 ? 203 LYS A CG 1 ATOM 1571 C CD . LYS A 1 203 ? 84.063 -4.159 -16.733 1.00 21.39 ? 203 LYS A CD 1 ATOM 1572 C CE . LYS A 1 203 ? 83.908 -5.469 -15.973 1.00 21.77 ? 203 LYS A CE 1 ATOM 1573 N NZ . LYS A 1 203 ? 83.905 -5.260 -14.497 1.00 22.21 ? 203 LYS A NZ 1 ATOM 1574 N N . GLY A 1 204 ? 87.999 -4.658 -20.733 1.00 13.28 ? 204 GLY A N 1 ATOM 1575 C CA . GLY A 1 204 ? 89.086 -5.356 -21.396 1.00 12.28 ? 204 GLY A CA 1 ATOM 1576 C C . GLY A 1 204 ? 90.433 -4.796 -20.983 1.00 13.08 ? 204 GLY A C 1 ATOM 1577 O O . GLY A 1 204 ? 90.498 -3.823 -20.231 1.00 14.24 ? 204 GLY A O 1 ATOM 1578 N N . ASN A 1 205 ? 91.506 -5.410 -21.473 1.00 13.04 ? 205 ASN A N 1 ATOM 1579 C CA . ASN A 1 205 ? 92.863 -4.966 -21.157 1.00 13.44 ? 205 ASN A CA 1 ATOM 1580 C C . ASN A 1 205 ? 93.277 -3.925 -22.195 1.00 13.65 ? 205 ASN A C 1 ATOM 1581 O O . ASN A 1 205 ? 93.352 -4.223 -23.388 1.00 13.16 ? 205 ASN A O 1 ATOM 1582 C CB . ASN A 1 205 ? 93.824 -6.158 -21.189 1.00 14.17 ? 205 ASN A CB 1 ATOM 1583 C CG . ASN A 1 205 ? 95.219 -5.796 -20.719 1.00 15.67 ? 205 ASN A CG 1 ATOM 1584 O OD1 . ASN A 1 205 ? 95.824 -4.848 -21.215 1.00 16.36 ? 205 ASN A OD1 1 ATOM 1585 N ND2 . ASN A 1 205 ? 95.739 -6.555 -19.760 1.00 17.71 ? 205 ASN A ND2 1 ATOM 1586 N N . SER A 1 206 ? 93.548 -2.708 -21.735 1.00 12.79 ? 206 SER A N 1 ATOM 1587 C CA . SER A 1 206 ? 93.915 -1.608 -22.621 1.00 14.45 ? 206 SER A CA 1 ATOM 1588 C C . SER A 1 206 ? 95.222 -1.775 -23.392 1.00 13.89 ? 206 SER A C 1 ATOM 1589 O O . SER A 1 206 ? 95.533 -0.961 -24.259 1.00 13.85 ? 206 SER A O 1 ATOM 1590 C CB . SER A 1 206 ? 93.951 -0.293 -21.836 1.00 16.46 ? 206 SER A CB 1 ATOM 1591 O OG . SER A 1 206 ? 94.934 -0.325 -20.818 1.00 19.66 ? 206 SER A OG 1 ATOM 1592 N N . ASN A 1 207 ? 95.987 -2.818 -23.079 1.00 12.03 ? 207 ASN A N 1 ATOM 1593 C CA . ASN A 1 207 ? 97.243 -3.064 -23.779 1.00 11.89 ? 207 ASN A CA 1 ATOM 1594 C C . ASN A 1 207 ? 97.075 -4.195 -24.792 1.00 10.37 ? 207 ASN A C 1 ATOM 1595 O O . ASN A 1 207 ? 97.957 -4.428 -25.619 1.00 11.72 ? 207 ASN A O 1 ATOM 1596 C CB . ASN A 1 207 ? 98.349 -3.440 -22.788 1.00 11.80 ? 207 ASN A CB 1 ATOM 1597 C CG . ASN A 1 207 ? 99.722 -3.505 -23.440 1.00 14.12 ? 207 ASN A CG 1 ATOM 1598 O OD1 . ASN A 1 207 ? 100.445 -4.492 -23.299 1.00 15.77 ? 207 ASN A OD1 1 ATOM 1599 N ND2 . ASN A 1 207 ? 100.090 -2.444 -24.149 1.00 12.60 ? 207 ASN A ND2 1 ATOM 1600 N N . ASN A 1 208 ? 95.941 -4.890 -24.731 1.00 11.47 ? 208 ASN A N 1 ATOM 1601 C CA . ASN A 1 208 ? 95.677 -6.009 -25.639 1.00 10.43 ? 208 ASN A CA 1 ATOM 1602 C C . ASN A 1 208 ? 94.509 -5.795 -26.595 1.00 10.81 ? 208 ASN A C 1 ATOM 1603 O O . ASN A 1 208 ? 94.403 -6.488 -27.603 1.00 11.11 ? 208 ASN A O 1 ATOM 1604 C CB . ASN A 1 208 ? 95.399 -7.295 -24.851 1.00 10.50 ? 208 ASN A CB 1 ATOM 1605 C CG . ASN A 1 208 ? 96.544 -7.687 -23.940 1.00 11.68 ? 208 ASN A CG 1 ATOM 1606 O OD1 . ASN A 1 208 ? 97.692 -7.300 -24.158 1.00 12.84 ? 208 ASN A OD1 1 ATOM 1607 N ND2 . ASN A 1 208 ? 96.238 -8.477 -22.920 1.00 11.80 ? 208 ASN A ND2 1 ATOM 1608 N N . LEU A 1 209 ? 93.637 -4.842 -26.281 1.00 10.02 ? 209 LEU A N 1 ATOM 1609 C CA . LEU A 1 209 ? 92.460 -4.588 -27.107 1.00 10.29 ? 209 LEU A CA 1 ATOM 1610 C C . LEU A 1 209 ? 92.576 -3.348 -27.984 1.00 11.64 ? 209 LEU A C 1 ATOM 1611 O O . LEU A 1 209 ? 92.953 -2.277 -27.514 1.00 12.15 ? 209 LEU A O 1 ATOM 1612 C CB . LEU A 1 209 ? 91.221 -4.467 -26.206 1.00 9.77 ? 209 LEU A CB 1 ATOM 1613 C CG . LEU A 1 209 ? 89.844 -4.214 -26.832 1.00 9.41 ? 209 LEU A CG 1 ATOM 1614 C CD1 . LEU A 1 209 ? 89.481 -5.343 -27.793 1.00 11.02 ? 209 LEU A CD1 1 ATOM 1615 C CD2 . LEU A 1 209 ? 88.804 -4.111 -25.719 1.00 12.05 ? 209 LEU A CD2 1 ATOM 1616 N N . ARG A 1 210 ? 92.255 -3.512 -29.264 1.00 11.60 ? 210 ARG A N 1 ATOM 1617 C CA . ARG A 1 210 ? 92.277 -2.413 -30.220 1.00 11.42 ? 210 ARG A CA 1 ATOM 1618 C C . ARG A 1 210 ? 90.942 -2.432 -30.948 1.00 12.35 ? 210 ARG A C 1 ATOM 1619 O O . ARG A 1 210 ? 90.460 -3.491 -31.358 1.00 11.71 ? 210 ARG A O 1 ATOM 1620 C CB . ARG A 1 210 ? 93.428 -2.570 -31.221 1.00 13.48 ? 210 ARG A CB 1 ATOM 1621 C CG . ARG A 1 210 ? 94.810 -2.346 -30.617 1.00 15.05 ? 210 ARG A CG 1 ATOM 1622 C CD . ARG A 1 210 ? 95.920 -2.699 -31.601 1.00 18.30 ? 210 ARG A CD 1 ATOM 1623 N NE A ARG A 1 210 ? 96.003 -1.777 -32.731 0.50 20.25 ? 210 ARG A NE 1 ATOM 1624 N NE B ARG A 1 210 ? 97.070 -1.802 -31.518 0.50 21.57 ? 210 ARG A NE 1 ATOM 1625 C CZ A ARG A 1 210 ? 96.531 -0.559 -32.667 0.50 21.15 ? 210 ARG A CZ 1 ATOM 1626 C CZ B ARG A 1 210 ? 97.819 -1.643 -30.432 0.50 22.74 ? 210 ARG A CZ 1 ATOM 1627 N NH1 A ARG A 1 210 ? 97.032 -0.107 -31.524 0.50 21.66 ? 210 ARG A NH1 1 ATOM 1628 N NH1 B ARG A 1 210 ? 97.546 -2.324 -29.326 0.50 23.37 ? 210 ARG A NH1 1 ATOM 1629 N NH2 A ARG A 1 210 ? 96.558 0.210 -33.747 0.50 21.28 ? 210 ARG A NH2 1 ATOM 1630 N NH2 B ARG A 1 210 ? 98.843 -0.800 -30.450 0.50 23.14 ? 210 ARG A NH2 1 ATOM 1631 N N . VAL A 1 211 ? 90.337 -1.258 -31.084 1.00 11.09 ? 211 VAL A N 1 ATOM 1632 C CA . VAL A 1 211 ? 89.050 -1.133 -31.752 1.00 10.89 ? 211 VAL A CA 1 ATOM 1633 C C . VAL A 1 211 ? 89.172 -0.239 -32.974 1.00 11.61 ? 211 VAL A C 1 ATOM 1634 O O . VAL A 1 211 ? 89.740 0.853 -32.907 1.00 12.04 ? 211 VAL A O 1 ATOM 1635 C CB . VAL A 1 211 ? 87.981 -0.524 -30.812 1.00 11.35 ? 211 VAL A CB 1 ATOM 1636 C CG1 . VAL A 1 211 ? 86.678 -0.320 -31.571 1.00 12.17 ? 211 VAL A CG1 1 ATOM 1637 C CG2 . VAL A 1 211 ? 87.766 -1.426 -29.605 1.00 10.56 ? 211 VAL A CG2 1 ATOM 1638 N N . GLY A 1 212 ? 88.644 -0.712 -34.095 1.00 10.40 ? 212 GLY A N 1 ATOM 1639 C CA . GLY A 1 212 ? 88.684 0.081 -35.303 1.00 11.10 ? 212 GLY A CA 1 ATOM 1640 C C . GLY A 1 212 ? 87.271 0.472 -35.683 1.00 10.84 ? 212 GLY A C 1 ATOM 1641 O O . GLY A 1 212 ? 86.381 -0.380 -35.726 1.00 12.29 ? 212 GLY A O 1 ATOM 1642 N N . VAL A 1 213 ? 87.045 1.758 -35.923 1.00 9.67 ? 213 VAL A N 1 ATOM 1643 C CA . VAL A 1 213 ? 85.722 2.213 -36.331 1.00 8.94 ? 213 VAL A CA 1 ATOM 1644 C C . VAL A 1 213 ? 85.785 2.636 -37.794 1.00 9.17 ? 213 VAL A C 1 ATOM 1645 O O . VAL A 1 213 ? 86.872 2.829 -38.345 1.00 9.13 ? 213 VAL A O 1 ATOM 1646 C CB . VAL A 1 213 ? 85.206 3.381 -35.452 1.00 10.50 ? 213 VAL A CB 1 ATOM 1647 C CG1 . VAL A 1 213 ? 84.942 2.879 -34.038 1.00 9.67 ? 213 VAL A CG1 1 ATOM 1648 C CG2 . VAL A 1 213 ? 86.215 4.520 -35.432 1.00 10.91 ? 213 VAL A CG2 1 ATOM 1649 N N . HIS A 1 214 ? 84.623 2.767 -38.426 1.00 9.81 ? 214 HIS A N 1 ATOM 1650 C CA . HIS A 1 214 ? 84.563 3.124 -39.840 1.00 10.84 ? 214 HIS A CA 1 ATOM 1651 C C . HIS A 1 214 ? 85.340 2.057 -40.607 1.00 10.43 ? 214 HIS A C 1 ATOM 1652 O O . HIS A 1 214 ? 86.044 2.350 -41.575 1.00 9.78 ? 214 HIS A O 1 ATOM 1653 C CB . HIS A 1 214 ? 85.187 4.504 -40.069 1.00 12.41 ? 214 HIS A CB 1 ATOM 1654 C CG . HIS A 1 214 ? 84.437 5.618 -39.410 1.00 13.78 ? 214 HIS A CG 1 ATOM 1655 N ND1 . HIS A 1 214 ? 85.053 6.771 -38.969 1.00 17.01 ? 214 HIS A ND1 1 ATOM 1656 C CD2 . HIS A 1 214 ? 83.122 5.763 -39.125 1.00 15.48 ? 214 HIS A CD2 1 ATOM 1657 C CE1 . HIS A 1 214 ? 84.149 7.576 -38.441 1.00 16.58 ? 214 HIS A CE1 1 ATOM 1658 N NE2 . HIS A 1 214 ? 82.968 6.988 -38.522 1.00 15.13 ? 214 HIS A NE2 1 ATOM 1659 N N . ALA A 1 215 ? 85.201 0.814 -40.153 1.00 10.44 ? 215 ALA A N 1 ATOM 1660 C CA . ALA A 1 215 ? 85.875 -0.329 -40.762 1.00 10.00 ? 215 ALA A CA 1 ATOM 1661 C C . ALA A 1 215 ? 84.833 -1.291 -41.313 1.00 9.94 ? 215 ALA A C 1 ATOM 1662 O O . ALA A 1 215 ? 84.153 -1.991 -40.558 1.00 10.40 ? 215 ALA A O 1 ATOM 1663 C CB . ALA A 1 215 ? 86.742 -1.032 -39.728 1.00 10.38 ? 215 ALA A CB 1 ATOM 1664 N N . SER A 1 216 ? 84.709 -1.319 -42.636 1.00 9.36 ? 216 SER A N 1 ATOM 1665 C CA . SER A 1 216 ? 83.739 -2.179 -43.300 1.00 9.51 ? 216 SER A CA 1 ATOM 1666 C C . SER A 1 216 ? 84.364 -3.519 -43.668 1.00 9.04 ? 216 SER A C 1 ATOM 1667 O O . SER A 1 216 ? 85.167 -3.596 -44.597 1.00 10.49 ? 216 SER A O 1 ATOM 1668 C CB . SER A 1 216 ? 83.210 -1.481 -44.559 1.00 10.74 ? 216 SER A CB 1 ATOM 1669 O OG . SER A 1 216 ? 82.247 -2.273 -45.234 1.00 10.48 ? 216 SER A OG 1 ATOM 1670 N N . VAL A 1 217 ? 84.001 -4.568 -42.933 1.00 8.64 ? 217 VAL A N 1 ATOM 1671 C CA . VAL A 1 217 ? 84.530 -5.904 -43.197 1.00 7.83 ? 217 VAL A CA 1 ATOM 1672 C C . VAL A 1 217 ? 83.779 -6.486 -44.390 1.00 7.99 ? 217 VAL A C 1 ATOM 1673 O O . VAL A 1 217 ? 82.563 -6.690 -44.340 1.00 7.51 ? 217 VAL A O 1 ATOM 1674 C CB . VAL A 1 217 ? 84.375 -6.814 -41.966 1.00 7.75 ? 217 VAL A CB 1 ATOM 1675 C CG1 . VAL A 1 217 ? 84.919 -8.200 -42.272 1.00 8.50 ? 217 VAL A CG1 1 ATOM 1676 C CG2 . VAL A 1 217 ? 85.121 -6.205 -40.778 1.00 8.48 ? 217 VAL A CG2 1 ATOM 1677 N N . GLU A 1 218 ? 84.521 -6.757 -45.459 1.00 8.66 ? 218 GLU A N 1 ATOM 1678 C CA . GLU A 1 218 ? 83.940 -7.246 -46.701 1.00 9.49 ? 218 GLU A CA 1 ATOM 1679 C C . GLU A 1 218 ? 84.054 -8.735 -46.968 1.00 10.40 ? 218 GLU A C 1 ATOM 1680 O O . GLU A 1 218 ? 83.233 -9.296 -47.695 1.00 12.17 ? 218 GLU A O 1 ATOM 1681 C CB . GLU A 1 218 ? 84.569 -6.509 -47.885 1.00 10.97 ? 218 GLU A CB 1 ATOM 1682 C CG . GLU A 1 218 ? 84.667 -5.006 -47.711 1.00 14.69 ? 218 GLU A CG 1 ATOM 1683 C CD . GLU A 1 218 ? 85.194 -4.322 -48.955 1.00 16.65 ? 218 GLU A CD 1 ATOM 1684 O OE1 . GLU A 1 218 ? 86.086 -4.898 -49.614 1.00 17.96 ? 218 GLU A OE1 1 ATOM 1685 O OE2 . GLU A 1 218 ? 84.727 -3.206 -49.267 1.00 19.29 ? 218 GLU A OE2 1 ATOM 1686 N N . LYS A 1 219 ? 85.057 -9.383 -46.391 1.00 9.94 ? 219 LYS A N 1 ATOM 1687 C CA . LYS A 1 219 ? 85.242 -10.799 -46.662 1.00 12.14 ? 219 LYS A CA 1 ATOM 1688 C C . LYS A 1 219 ? 86.132 -11.505 -45.648 1.00 12.04 ? 219 LYS A C 1 ATOM 1689 O O . LYS A 1 219 ? 87.061 -10.912 -45.099 1.00 10.94 ? 219 LYS A O 1 ATOM 1690 C CB . LYS A 1 219 ? 85.840 -10.945 -48.066 1.00 16.22 ? 219 LYS A CB 1 ATOM 1691 C CG . LYS A 1 219 ? 85.973 -12.361 -48.594 1.00 21.00 ? 219 LYS A CG 1 ATOM 1692 C CD . LYS A 1 219 ? 86.507 -12.329 -50.021 1.00 23.61 ? 219 LYS A CD 1 ATOM 1693 C CE . LYS A 1 219 ? 86.538 -13.712 -50.649 1.00 25.12 ? 219 LYS A CE 1 ATOM 1694 N NZ . LYS A 1 219 ? 86.980 -13.654 -52.073 1.00 28.30 ? 219 LYS A NZ 1 ATOM 1695 N N . ILE A 1 220 ? 85.825 -12.772 -45.391 1.00 10.24 ? 220 ILE A N 1 ATOM 1696 C CA . ILE A 1 220 ? 86.628 -13.583 -44.484 1.00 10.79 ? 220 ILE A CA 1 ATOM 1697 C C . ILE A 1 220 ? 87.642 -14.289 -45.381 1.00 11.19 ? 220 ILE A C 1 ATOM 1698 O O . ILE A 1 220 ? 87.293 -14.746 -46.469 1.00 12.49 ? 220 ILE A O 1 ATOM 1699 C CB . ILE A 1 220 ? 85.778 -14.649 -43.768 1.00 9.73 ? 220 ILE A CB 1 ATOM 1700 C CG1 . ILE A 1 220 ? 84.690 -13.972 -42.928 1.00 10.98 ? 220 ILE A CG1 1 ATOM 1701 C CG2 . ILE A 1 220 ? 86.670 -15.514 -42.881 1.00 10.59 ? 220 ILE A CG2 1 ATOM 1702 C CD1 . ILE A 1 220 ? 83.620 -14.922 -42.442 1.00 12.63 ? 220 ILE A CD1 1 ATOM 1703 N N . ILE A 1 221 ? 88.893 -14.359 -44.936 1.00 10.91 ? 221 ILE A N 1 ATOM 1704 C CA . ILE A 1 221 ? 89.948 -15.008 -45.710 1.00 12.83 ? 221 ILE A CA 1 ATOM 1705 C C . ILE A 1 221 ? 90.133 -16.433 -45.206 1.00 12.27 ? 221 ILE A C 1 ATOM 1706 O O . ILE A 1 221 ? 90.118 -16.670 -44.001 1.00 12.05 ? 221 ILE A O 1 ATOM 1707 C CB . ILE A 1 221 ? 91.291 -14.256 -45.564 1.00 14.46 ? 221 ILE A CB 1 ATOM 1708 C CG1 . ILE A 1 221 ? 91.109 -12.786 -45.945 1.00 15.34 ? 221 ILE A CG1 1 ATOM 1709 C CG2 . ILE A 1 221 ? 92.352 -14.907 -46.446 1.00 14.93 ? 221 ILE A CG2 1 ATOM 1710 C CD1 . ILE A 1 221 ? 92.341 -11.931 -45.709 1.00 17.38 ? 221 ILE A CD1 1 ATOM 1711 N N . PHE A 1 222 ? 90.302 -17.378 -46.126 1.00 12.64 ? 222 PHE A N 1 ATOM 1712 C CA . PHE A 1 222 ? 90.489 -18.776 -45.744 1.00 13.27 ? 222 PHE A CA 1 ATOM 1713 C C . PHE A 1 222 ? 91.755 -19.383 -46.329 1.00 15.97 ? 222 PHE A C 1 ATOM 1714 O O . PHE A 1 222 ? 92.395 -18.808 -47.210 1.00 14.73 ? 222 PHE A O 1 ATOM 1715 C CB . PHE A 1 222 ? 89.307 -19.638 -46.201 1.00 12.71 ? 222 PHE A CB 1 ATOM 1716 C CG . PHE A 1 222 ? 87.982 -19.210 -45.648 1.00 12.67 ? 222 PHE A CG 1 ATOM 1717 C CD1 . PHE A 1 222 ? 87.185 -18.303 -46.340 1.00 12.10 ? 222 PHE A CD1 1 ATOM 1718 C CD2 . PHE A 1 222 ? 87.525 -19.718 -44.438 1.00 12.54 ? 222 PHE A CD2 1 ATOM 1719 C CE1 . PHE A 1 222 ? 85.947 -17.910 -45.834 1.00 12.79 ? 222 PHE A CE1 1 ATOM 1720 C CE2 . PHE A 1 222 ? 86.290 -19.332 -43.922 1.00 13.08 ? 222 PHE A CE2 1 ATOM 1721 C CZ . PHE A 1 222 ? 85.498 -18.424 -44.623 1.00 13.11 ? 222 PHE A CZ 1 ATOM 1722 N N . SER A 1 223 ? 92.092 -20.563 -45.823 1.00 18.27 ? 223 SER A N 1 ATOM 1723 C CA . SER A 1 223 ? 93.247 -21.318 -46.278 1.00 21.06 ? 223 SER A CA 1 ATOM 1724 C C . SER A 1 223 ? 93.106 -22.730 -45.735 1.00 22.28 ? 223 SER A C 1 ATOM 1725 O O . SER A 1 223 ? 92.310 -22.985 -44.837 1.00 22.85 ? 223 SER A O 1 ATOM 1726 C CB . SER A 1 223 ? 94.547 -20.708 -45.753 1.00 22.31 ? 223 SER A CB 1 ATOM 1727 O OG . SER A 1 223 ? 94.730 -21.022 -44.384 1.00 25.70 ? 223 SER A OG 1 ATOM 1728 N N . ASN A 1 224 ? 93.880 -23.645 -46.296 1.00 24.03 ? 224 ASN A N 1 ATOM 1729 C CA . ASN A 1 224 ? 93.866 -25.032 -45.854 1.00 25.87 ? 224 ASN A CA 1 ATOM 1730 C C . ASN A 1 224 ? 95.172 -25.186 -45.093 1.00 26.15 ? 224 ASN A C 1 ATOM 1731 O O . ASN A 1 224 ? 96.237 -25.265 -45.707 1.00 27.07 ? 224 ASN A O 1 ATOM 1732 C CB . ASN A 1 224 ? 93.811 -25.969 -47.068 1.00 27.32 ? 224 ASN A CB 1 ATOM 1733 C CG . ASN A 1 224 ? 92.558 -25.764 -47.906 1.00 29.52 ? 224 ASN A CG 1 ATOM 1734 O OD1 . ASN A 1 224 ? 92.591 -25.855 -49.135 1.00 32.35 ? 224 ASN A OD1 1 ATOM 1735 N ND2 . ASN A 1 224 ? 91.443 -25.508 -47.241 1.00 30.29 ? 224 ASN A ND2 1 ATOM 1736 N N . ALA A 1 225 ? 95.092 -25.202 -43.761 1.00 26.81 ? 225 ALA A N 1 ATOM 1737 C CA . ALA A 1 225 ? 96.297 -25.303 -42.932 1.00 27.19 ? 225 ALA A CA 1 ATOM 1738 C C . ALA A 1 225 ? 96.324 -26.358 -41.807 1.00 26.81 ? 225 ALA A C 1 ATOM 1739 O O . ALA A 1 225 ? 96.538 -26.024 -40.638 1.00 27.78 ? 225 ALA A O 1 ATOM 1740 C CB . ALA A 1 225 ? 96.594 -23.946 -42.338 1.00 26.86 ? 225 ALA A CB 1 ATOM 1741 N N . PRO A 1 226 ? 96.160 -27.640 -42.158 1.00 25.60 ? 226 PRO A N 1 ATOM 1742 C CA . PRO A 1 226 ? 95.907 -28.210 -43.489 1.00 24.81 ? 226 PRO A CA 1 ATOM 1743 C C . PRO A 1 226 ? 94.430 -28.194 -43.882 1.00 23.06 ? 226 PRO A C 1 ATOM 1744 O O . PRO A 1 226 ? 94.092 -28.193 -45.064 1.00 23.86 ? 226 PRO A O 1 ATOM 1745 C CB . PRO A 1 226 ? 96.446 -29.631 -43.347 1.00 24.88 ? 226 PRO A CB 1 ATOM 1746 C CG . PRO A 1 226 ? 96.040 -29.968 -41.944 1.00 25.02 ? 226 PRO A CG 1 ATOM 1747 C CD . PRO A 1 226 ? 96.415 -28.717 -41.176 1.00 26.44 ? 226 PRO A CD 1 ATOM 1748 N N . GLY A 1 227 ? 93.555 -28.201 -42.878 1.00 21.67 ? 227 GLY A N 1 ATOM 1749 C CA . GLY A 1 227 ? 92.124 -28.193 -43.142 1.00 19.02 ? 227 GLY A CA 1 ATOM 1750 C C . GLY A 1 227 ? 91.605 -26.791 -43.388 1.00 17.78 ? 227 GLY A C 1 ATOM 1751 O O . GLY A 1 227 ? 92.303 -25.813 -43.111 1.00 17.06 ? 227 GLY A O 1 ATOM 1752 N N . LEU A 1 228 ? 90.388 -26.690 -43.915 1.00 15.44 ? 228 LEU A N 1 ATOM 1753 C CA . LEU A 1 228 ? 89.787 -25.388 -44.190 1.00 13.04 ? 228 LEU A CA 1 ATOM 1754 C C . LEU A 1 228 ? 89.775 -24.582 -42.897 1.00 11.92 ? 228 LEU A C 1 ATOM 1755 O O . LEU A 1 228 ? 89.193 -25.003 -41.897 1.00 10.85 ? 228 LEU A O 1 ATOM 1756 C CB . LEU A 1 228 ? 88.363 -25.560 -44.727 1.00 13.86 ? 228 LEU A CB 1 ATOM 1757 C CG . LEU A 1 228 ? 87.610 -24.267 -45.060 1.00 14.64 ? 228 LEU A CG 1 ATOM 1758 C CD1 . LEU A 1 228 ? 88.419 -23.420 -46.030 1.00 12.54 ? 228 LEU A CD1 1 ATOM 1759 C CD2 . LEU A 1 228 ? 86.250 -24.612 -45.652 1.00 14.09 ? 228 LEU A CD2 1 ATOM 1760 N N . THR A 1 229 ? 90.416 -23.417 -42.931 1.00 12.33 ? 229 THR A N 1 ATOM 1761 C CA . THR A 1 229 ? 90.526 -22.563 -41.754 1.00 12.61 ? 229 THR A CA 1 ATOM 1762 C C . THR A 1 229 ? 90.409 -21.077 -42.088 1.00 10.97 ? 229 THR A C 1 ATOM 1763 O O . THR A 1 229 ? 90.911 -20.627 -43.113 1.00 12.74 ? 229 THR A O 1 ATOM 1764 C CB . THR A 1 229 ? 91.897 -22.775 -41.070 1.00 13.74 ? 229 THR A CB 1 ATOM 1765 O OG1 . THR A 1 229 ? 92.087 -24.167 -40.792 1.00 15.90 ? 229 THR A OG1 1 ATOM 1766 C CG2 . THR A 1 229 ? 91.981 -21.989 -39.777 1.00 13.38 ? 229 THR A CG2 1 ATOM 1767 N N . ALA A 1 230 ? 89.742 -20.320 -41.219 1.00 9.78 ? 230 ALA A N 1 ATOM 1768 C CA . ALA A 1 230 ? 89.622 -18.877 -41.413 1.00 10.36 ? 230 ALA A CA 1 ATOM 1769 C C . ALA A 1 230 ? 90.951 -18.295 -40.930 1.00 10.91 ? 230 ALA A C 1 ATOM 1770 O O . ALA A 1 230 ? 91.417 -18.627 -39.838 1.00 12.44 ? 230 ALA A O 1 ATOM 1771 C CB . ALA A 1 230 ? 88.464 -18.324 -40.586 1.00 9.30 ? 230 ALA A CB 1 ATOM 1772 N N . THR A 1 231 ? 91.569 -17.439 -41.738 1.00 11.70 ? 231 THR A N 1 ATOM 1773 C CA . THR A 1 231 ? 92.861 -16.866 -41.369 1.00 11.11 ? 231 THR A CA 1 ATOM 1774 C C . THR A 1 231 ? 92.832 -15.370 -41.090 1.00 11.21 ? 231 THR A C 1 ATOM 1775 O O . THR A 1 231 ? 93.783 -14.820 -40.534 1.00 11.28 ? 231 THR A O 1 ATOM 1776 C CB . THR A 1 231 ? 93.904 -17.124 -42.467 1.00 13.20 ? 231 THR A CB 1 ATOM 1777 O OG1 . THR A 1 231 ? 93.488 -16.482 -43.677 1.00 14.34 ? 231 THR A OG1 1 ATOM 1778 C CG2 . THR A 1 231 ? 94.050 -18.617 -42.715 1.00 15.93 ? 231 THR A CG2 1 ATOM 1779 N N . GLY A 1 232 ? 91.749 -14.711 -41.476 1.00 9.03 ? 232 GLY A N 1 ATOM 1780 C CA . GLY A 1 232 ? 91.652 -13.281 -41.246 1.00 10.34 ? 232 GLY A CA 1 ATOM 1781 C C . GLY A 1 232 ? 90.495 -12.675 -42.003 1.00 10.24 ? 232 GLY A C 1 ATOM 1782 O O . GLY A 1 232 ? 89.600 -13.388 -42.449 1.00 10.38 ? 232 GLY A O 1 ATOM 1783 N N . VAL A 1 233 ? 90.509 -11.354 -42.149 1.00 10.51 ? 233 VAL A N 1 ATOM 1784 C CA . VAL A 1 233 ? 89.447 -10.665 -42.865 1.00 10.44 ? 233 VAL A CA 1 ATOM 1785 C C . VAL A 1 233 ? 89.989 -9.476 -43.635 1.00 10.79 ? 233 VAL A C 1 ATOM 1786 O O . VAL A 1 233 ? 91.080 -8.977 -43.356 1.00 9.98 ? 233 VAL A O 1 ATOM 1787 C CB . VAL A 1 233 ? 88.346 -10.136 -41.904 1.00 10.59 ? 233 VAL A CB 1 ATOM 1788 C CG1 . VAL A 1 233 ? 87.803 -11.269 -41.053 1.00 11.36 ? 233 VAL A CG1 1 ATOM 1789 C CG2 . VAL A 1 233 ? 88.904 -9.018 -41.024 1.00 11.71 ? 233 VAL A CG2 1 ATOM 1790 N N . ILE A 1 234 ? 89.214 -9.036 -44.617 1.00 11.17 ? 234 ILE A N 1 ATOM 1791 C CA . ILE A 1 234 ? 89.565 -7.871 -45.412 1.00 11.11 ? 234 ILE A CA 1 ATOM 1792 C C . ILE A 1 234 ? 88.544 -6.808 -45.040 1.00 9.36 ? 234 ILE A C 1 ATOM 1793 O O . ILE A 1 234 ? 87.342 -7.074 -45.047 1.00 10.96 ? 234 ILE A O 1 ATOM 1794 C CB . ILE A 1 234 ? 89.442 -8.148 -46.923 1.00 12.44 ? 234 ILE A CB 1 ATOM 1795 C CG1 . ILE A 1 234 ? 90.434 -9.232 -47.337 1.00 13.12 ? 234 ILE A CG1 1 ATOM 1796 C CG2 . ILE A 1 234 ? 89.691 -6.862 -47.710 1.00 12.02 ? 234 ILE A CG2 1 ATOM 1797 C CD1 . ILE A 1 234 ? 90.306 -9.656 -48.790 1.00 15.29 ? 234 ILE A CD1 1 ATOM 1798 N N . TYR A 1 235 ? 89.015 -5.617 -44.689 1.00 9.81 ? 235 TYR A N 1 ATOM 1799 C CA . TYR A 1 235 ? 88.104 -4.532 -44.352 1.00 10.39 ? 235 TYR A CA 1 ATOM 1800 C C . TYR A 1 235 ? 88.547 -3.279 -45.091 1.00 11.67 ? 235 TYR A C 1 ATOM 1801 O O . TYR A 1 235 ? 89.709 -3.160 -45.482 1.00 12.53 ? 235 TYR A O 1 ATOM 1802 C CB . TYR A 1 235 ? 88.056 -4.309 -42.831 1.00 10.40 ? 235 TYR A CB 1 ATOM 1803 C CG . TYR A 1 235 ? 89.354 -3.882 -42.177 1.00 10.15 ? 235 TYR A CG 1 ATOM 1804 C CD1 . TYR A 1 235 ? 89.646 -2.533 -41.982 1.00 11.33 ? 235 TYR A CD1 1 ATOM 1805 C CD2 . TYR A 1 235 ? 90.271 -4.828 -41.720 1.00 10.48 ? 235 TYR A CD2 1 ATOM 1806 C CE1 . TYR A 1 235 ? 90.818 -2.132 -41.341 1.00 11.72 ? 235 TYR A CE1 1 ATOM 1807 C CE2 . TYR A 1 235 ? 91.449 -4.441 -41.080 1.00 10.45 ? 235 TYR A CE2 1 ATOM 1808 C CZ . TYR A 1 235 ? 91.714 -3.089 -40.894 1.00 12.36 ? 235 TYR A CZ 1 ATOM 1809 O OH . TYR A 1 235 ? 92.876 -2.691 -40.274 1.00 12.57 ? 235 TYR A OH 1 ATOM 1810 N N . ARG A 1 236 ? 87.621 -2.350 -45.299 1.00 10.44 ? 236 ARG A N 1 ATOM 1811 C CA . ARG A 1 236 ? 87.942 -1.130 -46.031 1.00 13.59 ? 236 ARG A CA 1 ATOM 1812 C C . ARG A 1 236 ? 87.692 0.121 -45.195 1.00 13.49 ? 236 ARG A C 1 ATOM 1813 O O . ARG A 1 236 ? 86.759 0.157 -44.389 1.00 12.73 ? 236 ARG A O 1 ATOM 1814 C CB . ARG A 1 236 ? 87.108 -1.083 -47.317 1.00 15.56 ? 236 ARG A CB 1 ATOM 1815 C CG . ARG A 1 236 ? 87.605 -0.099 -48.364 1.00 18.92 ? 236 ARG A CG 1 ATOM 1816 C CD . ARG A 1 236 ? 86.816 -0.251 -49.654 1.00 20.09 ? 236 ARG A CD 1 ATOM 1817 N NE . ARG A 1 236 ? 86.917 -1.604 -50.198 1.00 22.38 ? 236 ARG A NE 1 ATOM 1818 C CZ . ARG A 1 236 ? 87.978 -2.082 -50.843 1.00 24.27 ? 236 ARG A CZ 1 ATOM 1819 N NH1 . ARG A 1 236 ? 89.046 -1.317 -51.039 1.00 24.49 ? 236 ARG A NH1 1 ATOM 1820 N NH2 . ARG A 1 236 ? 87.973 -3.330 -51.291 1.00 25.81 ? 236 ARG A NH2 1 ATOM 1821 N N . ASP A 1 237 ? 88.530 1.141 -45.378 1.00 14.54 ? 237 ASP A N 1 ATOM 1822 C CA . ASP A 1 237 ? 88.370 2.387 -44.633 1.00 15.36 ? 237 ASP A CA 1 ATOM 1823 C C . ASP A 1 237 ? 87.649 3.449 -45.457 1.00 16.33 ? 237 ASP A C 1 ATOM 1824 O O . ASP A 1 237 ? 87.291 3.213 -46.613 1.00 15.84 ? 237 ASP A O 1 ATOM 1825 C CB . ASP A 1 237 ? 89.727 2.925 -44.135 1.00 15.76 ? 237 ASP A CB 1 ATOM 1826 C CG . ASP A 1 237 ? 90.692 3.267 -45.265 1.00 17.83 ? 237 ASP A CG 1 ATOM 1827 O OD1 . ASP A 1 237 ? 90.240 3.713 -46.339 1.00 17.00 ? 237 ASP A OD1 1 ATOM 1828 O OD2 . ASP A 1 237 ? 91.917 3.113 -45.060 1.00 17.96 ? 237 ASP A OD2 1 ATOM 1829 N N . SER A 1 238 ? 87.435 4.617 -44.857 1.00 17.08 ? 238 SER A N 1 ATOM 1830 C CA . SER A 1 238 ? 86.729 5.707 -45.523 1.00 18.18 ? 238 SER A CA 1 ATOM 1831 C C . SER A 1 238 ? 87.421 6.258 -46.769 1.00 19.13 ? 238 SER A C 1 ATOM 1832 O O . SER A 1 238 ? 86.809 7.002 -47.537 1.00 19.54 ? 238 SER A O 1 ATOM 1833 C CB . SER A 1 238 ? 86.462 6.846 -44.530 1.00 15.67 ? 238 SER A CB 1 ATOM 1834 O OG . SER A 1 238 ? 87.659 7.314 -43.945 1.00 16.08 ? 238 SER A OG 1 ATOM 1835 N N . ASN A 1 239 ? 88.688 5.905 -46.972 1.00 19.88 ? 239 ASN A N 1 ATOM 1836 C CA . ASN A 1 239 ? 89.416 6.367 -48.153 1.00 21.34 ? 239 ASN A CA 1 ATOM 1837 C C . ASN A 1 239 ? 89.269 5.357 -49.278 1.00 21.00 ? 239 ASN A C 1 ATOM 1838 O O . ASN A 1 239 ? 89.670 5.614 -50.414 1.00 21.29 ? 239 ASN A O 1 ATOM 1839 C CB . ASN A 1 239 ? 90.906 6.555 -47.850 1.00 22.00 ? 239 ASN A CB 1 ATOM 1840 C CG . ASN A 1 239 ? 91.178 7.749 -46.963 1.00 23.24 ? 239 ASN A CG 1 ATOM 1841 O OD1 . ASN A 1 239 ? 90.587 8.815 -47.142 1.00 27.09 ? 239 ASN A OD1 1 ATOM 1842 N ND2 . ASN A 1 239 ? 92.090 7.586 -46.011 1.00 23.80 ? 239 ASN A ND2 1 ATOM 1843 N N . GLY A 1 240 ? 88.687 4.207 -48.954 1.00 20.37 ? 240 GLY A N 1 ATOM 1844 C CA . GLY A 1 240 ? 88.503 3.160 -49.942 1.00 19.80 ? 240 GLY A CA 1 ATOM 1845 C C . GLY A 1 240 ? 89.678 2.202 -49.933 1.00 17.81 ? 240 GLY A C 1 ATOM 1846 O O . GLY A 1 240 ? 89.740 1.275 -50.738 1.00 18.64 ? 240 GLY A O 1 ATOM 1847 N N . THR A 1 241 ? 90.613 2.432 -49.015 1.00 17.61 ? 241 THR A N 1 ATOM 1848 C CA . THR A 1 241 ? 91.806 1.602 -48.891 1.00 16.99 ? 241 THR A CA 1 ATOM 1849 C C . THR A 1 241 ? 91.510 0.314 -48.124 1.00 17.05 ? 241 THR A C 1 ATOM 1850 O O . THR A 1 241 ? 90.990 0.351 -47.010 1.00 14.78 ? 241 THR A O 1 ATOM 1851 C CB . THR A 1 241 ? 92.934 2.362 -48.157 1.00 19.41 ? 241 THR A CB 1 ATOM 1852 O OG1 . THR A 1 241 ? 93.252 3.565 -48.872 1.00 19.77 ? 241 THR A OG1 1 ATOM 1853 C CG2 . THR A 1 241 ? 94.179 1.499 -48.054 1.00 19.44 ? 241 THR A CG2 1 ATOM 1854 N N . PRO A 1 242 ? 91.829 -0.845 -48.721 1.00 16.19 ? 242 PRO A N 1 ATOM 1855 C CA . PRO A 1 242 ? 91.578 -2.120 -48.046 1.00 16.27 ? 242 PRO A CA 1 ATOM 1856 C C . PRO A 1 242 ? 92.729 -2.541 -47.137 1.00 16.32 ? 242 PRO A C 1 ATOM 1857 O O . PRO A 1 242 ? 93.901 -2.383 -47.484 1.00 17.44 ? 242 PRO A O 1 ATOM 1858 C CB . PRO A 1 242 ? 91.381 -3.083 -49.207 1.00 15.63 ? 242 PRO A CB 1 ATOM 1859 C CG . PRO A 1 242 ? 92.383 -2.567 -50.209 1.00 16.26 ? 242 PRO A CG 1 ATOM 1860 C CD . PRO A 1 242 ? 92.165 -1.061 -50.142 1.00 16.77 ? 242 PRO A CD 1 ATOM 1861 N N . HIS A 1 243 ? 92.379 -3.066 -45.968 1.00 14.04 ? 243 HIS A N 1 ATOM 1862 C CA . HIS A 1 243 ? 93.354 -3.537 -44.997 1.00 13.68 ? 243 HIS A CA 1 ATOM 1863 C C . HIS A 1 243 ? 93.080 -5.016 -44.770 1.00 13.98 ? 243 HIS A C 1 ATOM 1864 O O . HIS A 1 243 ? 92.036 -5.535 -45.171 1.00 14.33 ? 243 HIS A O 1 ATOM 1865 C CB . HIS A 1 243 ? 93.180 -2.849 -43.643 1.00 12.32 ? 243 HIS A CB 1 ATOM 1866 C CG . HIS A 1 243 ? 93.375 -1.367 -43.660 1.00 13.86 ? 243 HIS A CG 1 ATOM 1867 N ND1 . HIS A 1 243 ? 92.659 -0.525 -44.485 1.00 16.71 ? 243 HIS A ND1 1 ATOM 1868 C CD2 . HIS A 1 243 ? 94.148 -0.567 -42.888 1.00 14.23 ? 243 HIS A CD2 1 ATOM 1869 C CE1 . HIS A 1 243 ? 92.981 0.727 -44.217 1.00 13.61 ? 243 HIS A CE1 1 ATOM 1870 N NE2 . HIS A 1 243 ? 93.882 0.730 -43.251 1.00 16.28 ? 243 HIS A NE2 1 ATOM 1871 N N . GLN A 1 244 ? 94.015 -5.682 -44.107 1.00 13.53 ? 244 GLN A N 1 ATOM 1872 C CA . GLN A 1 244 ? 93.859 -7.090 -43.776 1.00 14.20 ? 244 GLN A CA 1 ATOM 1873 C C . GLN A 1 244 ? 94.277 -7.298 -42.329 1.00 12.99 ? 244 GLN A C 1 ATOM 1874 O O . GLN A 1 244 ? 95.252 -6.710 -41.869 1.00 13.40 ? 244 GLN A O 1 ATOM 1875 C CB . GLN A 1 244 ? 94.729 -7.968 -44.677 1.00 15.90 ? 244 GLN A CB 1 ATOM 1876 C CG . GLN A 1 244 ? 94.348 -7.945 -46.138 1.00 19.96 ? 244 GLN A CG 1 ATOM 1877 C CD . GLN A 1 244 ? 95.206 -8.881 -46.968 1.00 22.55 ? 244 GLN A CD 1 ATOM 1878 O OE1 . GLN A 1 244 ? 96.432 -8.756 -47.001 1.00 24.76 ? 244 GLN A OE1 1 ATOM 1879 N NE2 . GLN A 1 244 ? 94.565 -9.827 -47.643 1.00 25.02 ? 244 GLN A NE2 1 ATOM 1880 N N . ALA A 1 245 ? 93.525 -8.123 -41.613 1.00 12.02 ? 245 ALA A N 1 ATOM 1881 C CA . ALA A 1 245 ? 93.829 -8.444 -40.226 1.00 11.74 ? 245 ALA A CA 1 ATOM 1882 C C . ALA A 1 245 ? 93.815 -9.962 -40.147 1.00 12.44 ? 245 ALA A C 1 ATOM 1883 O O . ALA A 1 245 ? 92.805 -10.592 -40.462 1.00 13.27 ? 245 ALA A O 1 ATOM 1884 C CB . ALA A 1 245 ? 92.774 -7.856 -39.299 1.00 12.02 ? 245 ALA A CB 1 ATOM 1885 N N . PHE A 1 246 ? 94.940 -10.547 -39.750 1.00 11.68 ? 246 PHE A N 1 ATOM 1886 C CA . PHE A 1 246 ? 95.049 -11.996 -39.649 1.00 12.00 ? 246 PHE A CA 1 ATOM 1887 C C . PHE A 1 246 ? 95.152 -12.456 -38.204 1.00 12.15 ? 246 PHE A C 1 ATOM 1888 O O . PHE A 1 246 ? 95.531 -11.687 -37.320 1.00 11.87 ? 246 PHE A O 1 ATOM 1889 C CB . PHE A 1 246 ? 96.281 -12.505 -40.405 1.00 12.63 ? 246 PHE A CB 1 ATOM 1890 C CG . PHE A 1 246 ? 96.261 -12.219 -41.877 1.00 13.07 ? 246 PHE A CG 1 ATOM 1891 C CD1 . PHE A 1 246 ? 96.755 -11.019 -42.375 1.00 15.55 ? 246 PHE A CD1 1 ATOM 1892 C CD2 . PHE A 1 246 ? 95.754 -13.157 -42.769 1.00 15.14 ? 246 PHE A CD2 1 ATOM 1893 C CE1 . PHE A 1 246 ? 96.746 -10.759 -43.747 1.00 17.15 ? 246 PHE A CE1 1 ATOM 1894 C CE2 . PHE A 1 246 ? 95.740 -12.907 -44.139 1.00 16.43 ? 246 PHE A CE2 1 ATOM 1895 C CZ . PHE A 1 246 ? 96.236 -11.707 -44.627 1.00 15.88 ? 246 PHE A CZ 1 ATOM 1896 N N . VAL A 1 247 ? 94.819 -13.722 -37.975 1.00 12.91 ? 247 VAL A N 1 ATOM 1897 C CA . VAL A 1 247 ? 94.900 -14.304 -36.642 1.00 12.69 ? 247 VAL A CA 1 ATOM 1898 C C . VAL A 1 247 ? 96.033 -15.324 -36.625 1.00 13.01 ? 247 VAL A C 1 ATOM 1899 O O . VAL A 1 247 ? 96.291 -15.998 -37.623 1.00 15.13 ? 247 VAL A O 1 ATOM 1900 C CB . VAL A 1 247 ? 93.575 -14.991 -36.238 1.00 13.27 ? 247 VAL A CB 1 ATOM 1901 C CG1 . VAL A 1 247 ? 92.467 -13.948 -36.138 1.00 13.07 ? 247 VAL A CG1 1 ATOM 1902 C CG2 . VAL A 1 247 ? 93.204 -16.063 -37.247 1.00 13.19 ? 247 VAL A CG2 1 ATOM 1903 N N . ARG A 1 248 ? 96.711 -15.428 -35.488 1.00 13.18 ? 248 ARG A N 1 ATOM 1904 C CA . ARG A 1 248 ? 97.826 -16.351 -35.347 1.00 13.44 ? 248 ARG A CA 1 ATOM 1905 C C . ARG A 1 248 ? 97.397 -17.734 -34.864 1.00 14.26 ? 248 ARG A C 1 ATOM 1906 O O . ARG A 1 248 ? 96.217 -17.984 -34.629 1.00 16.04 ? 248 ARG A O 1 ATOM 1907 C CB . ARG A 1 248 ? 98.870 -15.755 -34.400 1.00 13.32 ? 248 ARG A CB 1 ATOM 1908 C CG . ARG A 1 248 ? 99.468 -14.445 -34.915 1.00 15.15 ? 248 ARG A CG 1 ATOM 1909 C CD . ARG A 1 248 ? 100.752 -14.071 -34.186 1.00 14.82 ? 248 ARG A CD 1 ATOM 1910 N NE . ARG A 1 248 ? 100.524 -13.576 -32.829 1.00 16.20 ? 248 ARG A NE 1 ATOM 1911 C CZ . ARG A 1 248 ? 100.305 -12.301 -32.518 1.00 15.26 ? 248 ARG A CZ 1 ATOM 1912 N NH1 . ARG A 1 248 ? 100.280 -11.373 -33.464 1.00 13.74 ? 248 ARG A NH1 1 ATOM 1913 N NH2 . ARG A 1 248 ? 100.118 -11.949 -31.254 1.00 15.75 ? 248 ARG A NH2 1 ATOM 1914 N N . SER A 1 249 ? 98.367 -18.632 -34.728 1.00 15.65 ? 249 SER A N 1 ATOM 1915 C CA . SER A 1 249 ? 98.097 -19.997 -34.287 1.00 16.80 ? 249 SER A CA 1 ATOM 1916 C C . SER A 1 249 ? 97.140 -20.060 -33.100 1.00 16.86 ? 249 SER A C 1 ATOM 1917 O O . SER A 1 249 ? 97.308 -19.341 -32.112 1.00 17.91 ? 249 SER A O 1 ATOM 1918 C CB . SER A 1 249 ? 99.410 -20.699 -33.925 1.00 18.11 ? 249 SER A CB 1 ATOM 1919 O OG . SER A 1 249 ? 99.178 -22.045 -33.544 1.00 21.11 ? 249 SER A OG 1 ATOM 1920 N N . LYS A 1 250 ? 96.139 -20.932 -33.213 1.00 16.16 ? 250 LYS A N 1 ATOM 1921 C CA . LYS A 1 250 ? 95.127 -21.137 -32.179 1.00 16.75 ? 250 LYS A CA 1 ATOM 1922 C C . LYS A 1 250 ? 94.126 -19.992 -32.061 1.00 14.99 ? 250 LYS A C 1 ATOM 1923 O O . LYS A 1 250 ? 93.149 -20.096 -31.320 1.00 15.70 ? 250 LYS A O 1 ATOM 1924 C CB . LYS A 1 250 ? 95.785 -21.374 -30.815 1.00 19.51 ? 250 LYS A CB 1 ATOM 1925 C CG . LYS A 1 250 ? 96.586 -22.664 -30.719 1.00 23.72 ? 250 LYS A CG 1 ATOM 1926 C CD . LYS A 1 250 ? 97.026 -22.914 -29.285 1.00 26.53 ? 250 LYS A CD 1 ATOM 1927 C CE . LYS A 1 250 ? 97.786 -24.219 -29.148 1.00 29.23 ? 250 LYS A CE 1 ATOM 1928 N NZ . LYS A 1 250 ? 98.126 -24.494 -27.724 1.00 31.80 ? 250 LYS A NZ 1 ATOM 1929 N N . GLY A 1 251 ? 94.374 -18.907 -32.789 1.00 13.90 ? 251 GLY A N 1 ATOM 1930 C CA . GLY A 1 251 ? 93.477 -17.763 -32.751 1.00 12.53 ? 251 GLY A CA 1 ATOM 1931 C C . GLY A 1 251 ? 92.265 -17.972 -33.639 1.00 11.43 ? 251 GLY A C 1 ATOM 1932 O O . GLY A 1 251 ? 92.219 -18.928 -34.411 1.00 11.39 ? 251 GLY A O 1 ATOM 1933 N N . GLU A 1 252 ? 91.286 -17.075 -33.554 1.00 10.24 ? 252 GLU A N 1 ATOM 1934 C CA . GLU A 1 252 ? 90.081 -17.237 -34.358 1.00 9.50 ? 252 GLU A CA 1 ATOM 1935 C C . GLU A 1 252 ? 89.440 -15.943 -34.824 1.00 9.49 ? 252 GLU A C 1 ATOM 1936 O O . GLU A 1 252 ? 89.673 -14.869 -34.267 1.00 8.73 ? 252 GLU A O 1 ATOM 1937 C CB . GLU A 1 252 ? 89.029 -18.018 -33.563 1.00 11.53 ? 252 GLU A CB 1 ATOM 1938 C CG . GLU A 1 252 ? 89.542 -19.295 -32.920 1.00 13.48 ? 252 GLU A CG 1 ATOM 1939 C CD . GLU A 1 252 ? 88.468 -20.018 -32.137 1.00 15.63 ? 252 GLU A CD 1 ATOM 1940 O OE1 . GLU A 1 252 ? 87.396 -20.288 -32.717 1.00 16.46 ? 252 GLU A OE1 1 ATOM 1941 O OE2 . GLU A 1 252 ? 88.694 -20.321 -30.946 1.00 14.10 ? 252 GLU A OE2 1 ATOM 1942 N N . VAL A 1 253 ? 88.638 -16.069 -35.873 1.00 8.28 ? 253 VAL A N 1 ATOM 1943 C CA . VAL A 1 253 ? 87.876 -14.955 -36.406 1.00 8.67 ? 253 VAL A CA 1 ATOM 1944 C C . VAL A 1 253 ? 86.477 -15.233 -35.873 1.00 9.14 ? 253 VAL A C 1 ATOM 1945 O O . VAL A 1 253 ? 85.962 -16.345 -36.018 1.00 8.69 ? 253 VAL A O 1 ATOM 1946 C CB . VAL A 1 253 ? 87.824 -14.967 -37.949 1.00 7.97 ? 253 VAL A CB 1 ATOM 1947 C CG1 . VAL A 1 253 ? 86.791 -13.955 -38.441 1.00 9.97 ? 253 VAL A CG1 1 ATOM 1948 C CG2 . VAL A 1 253 ? 89.198 -14.639 -38.523 1.00 9.36 ? 253 VAL A CG2 1 ATOM 1949 N N . ILE A 1 254 ? 85.871 -14.244 -35.232 1.00 8.00 ? 254 ILE A N 1 ATOM 1950 C CA . ILE A 1 254 ? 84.528 -14.418 -34.702 1.00 7.81 ? 254 ILE A CA 1 ATOM 1951 C C . ILE A 1 254 ? 83.652 -13.339 -35.307 1.00 7.71 ? 254 ILE A C 1 ATOM 1952 O O . ILE A 1 254 ? 83.971 -12.150 -35.225 1.00 8.47 ? 254 ILE A O 1 ATOM 1953 C CB . ILE A 1 254 ? 84.509 -14.300 -33.167 1.00 8.35 ? 254 ILE A CB 1 ATOM 1954 C CG1 . ILE A 1 254 ? 85.489 -15.314 -32.565 1.00 11.40 ? 254 ILE A CG1 1 ATOM 1955 C CG2 . ILE A 1 254 ? 83.102 -14.556 -32.649 1.00 10.97 ? 254 ILE A CG2 1 ATOM 1956 C CD1 . ILE A 1 254 ? 85.777 -15.110 -31.095 1.00 12.84 ? 254 ILE A CD1 1 ATOM 1957 N N . VAL A 1 255 ? 82.559 -13.764 -35.932 1.00 7.16 ? 255 VAL A N 1 ATOM 1958 C CA . VAL A 1 255 ? 81.631 -12.841 -36.566 1.00 6.99 ? 255 VAL A CA 1 ATOM 1959 C C . VAL A 1 255 ? 80.497 -12.506 -35.602 1.00 5.81 ? 255 VAL A C 1 ATOM 1960 O O . VAL A 1 255 ? 79.775 -13.391 -35.142 1.00 6.88 ? 255 VAL A O 1 ATOM 1961 C CB . VAL A 1 255 ? 81.052 -13.452 -37.861 1.00 6.21 ? 255 VAL A CB 1 ATOM 1962 C CG1 . VAL A 1 255 ? 80.223 -12.404 -38.607 1.00 7.47 ? 255 VAL A CG1 1 ATOM 1963 C CG2 . VAL A 1 255 ? 82.189 -13.956 -38.746 1.00 8.43 ? 255 VAL A CG2 1 ATOM 1964 N N . SER A 1 256 ? 80.364 -11.218 -35.294 1.00 5.89 ? 256 SER A N 1 ATOM 1965 C CA . SER A 1 256 ? 79.335 -10.720 -34.387 1.00 5.90 ? 256 SER A CA 1 ATOM 1966 C C . SER A 1 256 ? 78.679 -9.532 -35.079 1.00 6.51 ? 256 SER A C 1 ATOM 1967 O O . SER A 1 256 ? 78.392 -8.508 -34.452 1.00 6.59 ? 256 SER A O 1 ATOM 1968 C CB . SER A 1 256 ? 79.975 -10.267 -33.070 1.00 7.24 ? 256 SER A CB 1 ATOM 1969 O OG . SER A 1 256 ? 80.664 -11.339 -32.443 1.00 7.66 ? 256 SER A OG 1 ATOM 1970 N N . ALA A 1 257 ? 78.438 -9.689 -36.378 1.00 5.95 ? 257 ALA A N 1 ATOM 1971 C CA . ALA A 1 257 ? 77.860 -8.636 -37.207 1.00 5.42 ? 257 ALA A CA 1 ATOM 1972 C C . ALA A 1 257 ? 76.338 -8.546 -37.161 1.00 7.49 ? 257 ALA A C 1 ATOM 1973 O O . ALA A 1 257 ? 75.737 -7.782 -37.919 1.00 7.81 ? 257 ALA A O 1 ATOM 1974 C CB . ALA A 1 257 ? 78.330 -8.808 -38.646 1.00 5.91 ? 257 ALA A CB 1 ATOM 1975 N N . GLY A 1 258 ? 75.719 -9.328 -36.281 1.00 5.75 ? 258 GLY A N 1 ATOM 1976 C CA . GLY A 1 258 ? 74.274 -9.291 -36.141 1.00 7.39 ? 258 GLY A CA 1 ATOM 1977 C C . GLY A 1 258 ? 73.473 -10.207 -37.044 1.00 7.52 ? 258 GLY A C 1 ATOM 1978 O O . GLY A 1 258 ? 74.001 -10.799 -37.986 1.00 7.48 ? 258 GLY A O 1 ATOM 1979 N N . THR A 1 259 ? 72.183 -10.312 -36.741 1.00 6.93 ? 259 THR A N 1 ATOM 1980 C CA . THR A 1 259 ? 71.245 -11.137 -37.495 1.00 6.88 ? 259 THR A CA 1 ATOM 1981 C C . THR A 1 259 ? 71.298 -10.843 -38.993 1.00 7.42 ? 259 THR A C 1 ATOM 1982 O O . THR A 1 259 ? 71.192 -11.750 -39.818 1.00 7.57 ? 259 THR A O 1 ATOM 1983 C CB . THR A 1 259 ? 69.804 -10.903 -36.984 1.00 7.52 ? 259 THR A CB 1 ATOM 1984 O OG1 . THR A 1 259 ? 69.719 -11.320 -35.615 1.00 9.10 ? 259 THR A OG1 1 ATOM 1985 C CG2 . THR A 1 259 ? 68.791 -11.676 -37.817 1.00 6.44 ? 259 THR A CG2 1 ATOM 1986 N N . ILE A 1 260 ? 71.462 -9.572 -39.344 1.00 6.93 ? 260 ILE A N 1 ATOM 1987 C CA . ILE A 1 260 ? 71.519 -9.188 -40.747 1.00 7.62 ? 260 ILE A CA 1 ATOM 1988 C C . ILE A 1 260 ? 72.942 -9.244 -41.304 1.00 8.37 ? 260 ILE A C 1 ATOM 1989 O O . ILE A 1 260 ? 73.173 -9.800 -42.377 1.00 9.19 ? 260 ILE A O 1 ATOM 1990 C CB . ILE A 1 260 ? 70.964 -7.752 -40.955 1.00 9.38 ? 260 ILE A CB 1 ATOM 1991 C CG1 . ILE A 1 260 ? 69.533 -7.651 -40.415 1.00 11.06 ? 260 ILE A CG1 1 ATOM 1992 C CG2 . ILE A 1 260 ? 71.015 -7.382 -42.427 1.00 8.95 ? 260 ILE A CG2 1 ATOM 1993 C CD1 . ILE A 1 260 ? 68.530 -8.544 -41.112 1.00 15.12 ? 260 ILE A CD1 1 ATOM 1994 N N . GLY A 1 261 ? 73.891 -8.681 -40.559 1.00 7.91 ? 261 GLY A N 1 ATOM 1995 C CA . GLY A 1 261 ? 75.272 -8.639 -41.008 1.00 7.28 ? 261 GLY A CA 1 ATOM 1996 C C . GLY A 1 261 ? 76.079 -9.925 -41.052 1.00 6.98 ? 261 GLY A C 1 ATOM 1997 O O . GLY A 1 261 ? 76.942 -10.076 -41.915 1.00 7.53 ? 261 GLY A O 1 ATOM 1998 N N . THR A 1 262 ? 75.824 -10.846 -40.132 1.00 7.47 ? 262 THR A N 1 ATOM 1999 C CA . THR A 1 262 ? 76.581 -12.093 -40.115 1.00 6.63 ? 262 THR A CA 1 ATOM 2000 C C . THR A 1 262 ? 76.285 -12.991 -41.317 1.00 7.42 ? 262 THR A C 1 ATOM 2001 O O . THR A 1 262 ? 77.209 -13.399 -42.024 1.00 8.09 ? 262 THR A O 1 ATOM 2002 C CB . THR A 1 262 ? 76.361 -12.839 -38.786 1.00 6.51 ? 262 THR A CB 1 ATOM 2003 O OG1 . THR A 1 262 ? 77.019 -12.112 -37.741 1.00 7.32 ? 262 THR A OG1 1 ATOM 2004 C CG2 . THR A 1 262 ? 76.929 -14.252 -38.845 1.00 8.47 ? 262 THR A CG2 1 ATOM 2005 N N . PRO A 1 263 ? 75.005 -13.304 -41.579 1.00 7.12 ? 263 PRO A N 1 ATOM 2006 C CA . PRO A 1 263 ? 74.729 -14.159 -42.739 1.00 7.43 ? 263 PRO A CA 1 ATOM 2007 C C . PRO A 1 263 ? 75.222 -13.502 -44.032 1.00 7.84 ? 263 PRO A C 1 ATOM 2008 O O . PRO A 1 263 ? 75.714 -14.176 -44.934 1.00 8.10 ? 263 PRO A O 1 ATOM 2009 C CB . PRO A 1 263 ? 73.206 -14.303 -42.712 1.00 8.48 ? 263 PRO A CB 1 ATOM 2010 C CG . PRO A 1 263 ? 72.878 -14.188 -41.253 1.00 8.72 ? 263 PRO A CG 1 ATOM 2011 C CD . PRO A 1 263 ? 73.779 -13.058 -40.799 1.00 7.83 ? 263 PRO A CD 1 ATOM 2012 N N . GLN A 1 264 ? 75.088 -12.180 -44.117 1.00 8.47 ? 264 GLN A N 1 ATOM 2013 C CA . GLN A 1 264 ? 75.534 -11.449 -45.300 1.00 7.44 ? 264 GLN A CA 1 ATOM 2014 C C . GLN A 1 264 ? 77.028 -11.637 -45.545 1.00 7.41 ? 264 GLN A C 1 ATOM 2015 O O . GLN A 1 264 ? 77.452 -11.909 -46.671 1.00 7.80 ? 264 GLN A O 1 ATOM 2016 C CB . GLN A 1 264 ? 75.233 -9.955 -45.154 1.00 6.18 ? 264 GLN A CB 1 ATOM 2017 C CG . GLN A 1 264 ? 75.821 -9.110 -46.274 1.00 8.02 ? 264 GLN A CG 1 ATOM 2018 C CD . GLN A 1 264 ? 75.645 -7.622 -46.038 1.00 10.48 ? 264 GLN A CD 1 ATOM 2019 O OE1 . GLN A 1 264 ? 75.844 -7.132 -44.928 1.00 10.23 ? 264 GLN A OE1 1 ATOM 2020 N NE2 . GLN A 1 264 ? 75.288 -6.893 -47.090 1.00 8.99 ? 264 GLN A NE2 1 ATOM 2021 N N . LEU A 1 265 ? 77.827 -11.484 -44.491 1.00 6.65 ? 265 LEU A N 1 ATOM 2022 C CA . LEU A 1 265 ? 79.271 -11.635 -44.616 1.00 7.51 ? 265 LEU A CA 1 ATOM 2023 C C . LEU A 1 265 ? 79.656 -13.069 -44.977 1.00 6.70 ? 265 LEU A C 1 ATOM 2024 O O . LEU A 1 265 ? 80.556 -13.282 -45.788 1.00 7.23 ? 265 LEU A O 1 ATOM 2025 C CB . LEU A 1 265 ? 79.970 -11.219 -43.318 1.00 7.55 ? 265 LEU A CB 1 ATOM 2026 C CG . LEU A 1 265 ? 81.495 -11.364 -43.344 1.00 7.66 ? 265 LEU A CG 1 ATOM 2027 C CD1 . LEU A 1 265 ? 82.086 -10.517 -44.461 1.00 9.03 ? 265 LEU A CD1 1 ATOM 2028 C CD2 . LEU A 1 265 ? 82.070 -10.948 -41.999 1.00 9.14 ? 265 LEU A CD2 1 ATOM 2029 N N . LEU A 1 266 ? 78.980 -14.047 -44.378 1.00 8.11 ? 266 LEU A N 1 ATOM 2030 C CA . LEU A 1 266 ? 79.268 -15.446 -44.673 1.00 7.17 ? 266 LEU A CA 1 ATOM 2031 C C . LEU A 1 266 ? 78.997 -15.732 -46.150 1.00 6.62 ? 266 LEU A C 1 ATOM 2032 O O . LEU A 1 266 ? 79.823 -16.332 -46.831 1.00 7.61 ? 266 LEU A O 1 ATOM 2033 C CB . LEU A 1 266 ? 78.423 -16.369 -43.787 1.00 7.61 ? 266 LEU A CB 1 ATOM 2034 C CG . LEU A 1 266 ? 78.849 -16.429 -42.315 1.00 8.26 ? 266 LEU A CG 1 ATOM 2035 C CD1 . LEU A 1 266 ? 77.846 -17.255 -41.521 1.00 8.41 ? 266 LEU A CD1 1 ATOM 2036 C CD2 . LEU A 1 266 ? 80.249 -17.035 -42.209 1.00 8.90 ? 266 LEU A CD2 1 ATOM 2037 N N . LEU A 1 267 ? 77.845 -15.288 -46.646 1.00 7.33 ? 267 LEU A N 1 ATOM 2038 C CA . LEU A 1 267 ? 77.501 -15.496 -48.048 1.00 7.78 ? 267 LEU A CA 1 ATOM 2039 C C . LEU A 1 267 ? 78.536 -14.833 -48.955 1.00 8.21 ? 267 LEU A C 1 ATOM 2040 O O . LEU A 1 267 ? 79.034 -15.448 -49.894 1.00 9.71 ? 267 LEU A O 1 ATOM 2041 C CB . LEU A 1 267 ? 76.110 -14.928 -48.346 1.00 7.92 ? 267 LEU A CB 1 ATOM 2042 C CG . LEU A 1 267 ? 74.942 -15.639 -47.655 1.00 7.07 ? 267 LEU A CG 1 ATOM 2043 C CD1 . LEU A 1 267 ? 73.639 -14.898 -47.942 1.00 8.92 ? 267 LEU A CD1 1 ATOM 2044 C CD2 . LEU A 1 267 ? 74.854 -17.082 -48.145 1.00 8.61 ? 267 LEU A CD2 1 ATOM 2045 N N . LEU A 1 268 ? 78.859 -13.577 -48.669 1.00 8.03 ? 268 LEU A N 1 ATOM 2046 C CA . LEU A 1 268 ? 79.834 -12.847 -49.467 1.00 8.52 ? 268 LEU A CA 1 ATOM 2047 C C . LEU A 1 268 ? 81.210 -13.505 -49.438 1.00 9.52 ? 268 LEU A C 1 ATOM 2048 O O . LEU A 1 268 ? 82.020 -13.307 -50.346 1.00 11.68 ? 268 LEU A O 1 ATOM 2049 C CB . LEU A 1 268 ? 79.946 -11.401 -48.974 1.00 8.20 ? 268 LEU A CB 1 ATOM 2050 C CG . LEU A 1 268 ? 78.799 -10.460 -49.347 1.00 8.79 ? 268 LEU A CG 1 ATOM 2051 C CD1 . LEU A 1 268 ? 78.925 -9.154 -48.571 1.00 8.88 ? 268 LEU A CD1 1 ATOM 2052 C CD2 . LEU A 1 268 ? 78.825 -10.205 -50.855 1.00 8.50 ? 268 LEU A CD2 1 ATOM 2053 N N . SER A 1 269 ? 81.463 -14.292 -48.395 1.00 8.23 ? 269 SER A N 1 ATOM 2054 C CA . SER A 1 269 ? 82.742 -14.975 -48.231 1.00 8.73 ? 269 SER A CA 1 ATOM 2055 C C . SER A 1 269 ? 82.745 -16.400 -48.777 1.00 10.03 ? 269 SER A C 1 ATOM 2056 O O . SER A 1 269 ? 83.724 -17.129 -48.617 1.00 11.49 ? 269 SER A O 1 ATOM 2057 C CB . SER A 1 269 ? 83.133 -14.995 -46.752 1.00 9.50 ? 269 SER A CB 1 ATOM 2058 O OG . SER A 1 269 ? 83.230 -13.673 -46.253 1.00 8.29 ? 269 SER A OG 1 ATOM 2059 N N . GLY A 1 270 ? 81.646 -16.801 -49.406 1.00 9.66 ? 270 GLY A N 1 ATOM 2060 C CA . GLY A 1 270 ? 81.582 -18.135 -49.977 1.00 9.57 ? 270 GLY A CA 1 ATOM 2061 C C . GLY A 1 270 ? 81.114 -19.252 -49.064 1.00 10.18 ? 270 GLY A C 1 ATOM 2062 O O . GLY A 1 270 ? 81.335 -20.427 -49.363 1.00 10.65 ? 270 GLY A O 1 ATOM 2063 N N . VAL A 1 271 ? 80.479 -18.907 -47.950 1.00 8.15 ? 271 VAL A N 1 ATOM 2064 C CA . VAL A 1 271 ? 79.970 -19.922 -47.033 1.00 9.54 ? 271 VAL A CA 1 ATOM 2065 C C . VAL A 1 271 ? 78.448 -19.833 -47.034 1.00 10.56 ? 271 VAL A C 1 ATOM 2066 O O . VAL A 1 271 ? 77.864 -18.928 -46.433 1.00 10.61 ? 271 VAL A O 1 ATOM 2067 C CB . VAL A 1 271 ? 80.505 -19.712 -45.598 1.00 8.75 ? 271 VAL A CB 1 ATOM 2068 C CG1 . VAL A 1 271 ? 79.950 -20.782 -44.672 1.00 9.63 ? 271 VAL A CG1 1 ATOM 2069 C CG2 . VAL A 1 271 ? 82.022 -19.764 -45.599 1.00 8.86 ? 271 VAL A CG2 1 ATOM 2070 N N . GLY A 1 272 ? 77.812 -20.770 -47.731 1.00 9.46 ? 272 GLY A N 1 ATOM 2071 C CA . GLY A 1 272 ? 76.365 -20.777 -47.821 1.00 10.62 ? 272 GLY A CA 1 ATOM 2072 C C . GLY A 1 272 ? 75.882 -21.794 -48.838 1.00 10.26 ? 272 GLY A C 1 ATOM 2073 O O . GLY A 1 272 ? 76.665 -22.641 -49.272 1.00 9.93 ? 272 GLY A O 1 ATOM 2074 N N . PRO A 1 273 ? 74.602 -21.733 -49.245 1.00 11.61 ? 273 PRO A N 1 ATOM 2075 C CA . PRO A 1 273 ? 74.020 -22.662 -50.220 1.00 12.40 ? 273 PRO A CA 1 ATOM 2076 C C . PRO A 1 273 ? 74.825 -22.690 -51.516 1.00 13.21 ? 273 PRO A C 1 ATOM 2077 O O . PRO A 1 273 ? 74.957 -21.678 -52.200 1.00 11.39 ? 273 PRO A O 1 ATOM 2078 C CB . PRO A 1 273 ? 72.613 -22.108 -50.423 1.00 13.91 ? 273 PRO A CB 1 ATOM 2079 C CG . PRO A 1 273 ? 72.308 -21.480 -49.094 1.00 12.67 ? 273 PRO A CG 1 ATOM 2080 C CD . PRO A 1 273 ? 73.594 -20.756 -48.799 1.00 13.00 ? 273 PRO A CD 1 ATOM 2081 N N . GLU A 1 274 ? 75.351 -23.861 -51.850 1.00 13.13 ? 274 GLU A N 1 ATOM 2082 C CA . GLU A 1 274 ? 76.163 -24.025 -53.046 1.00 14.18 ? 274 GLU A CA 1 ATOM 2083 C C . GLU A 1 274 ? 75.515 -23.499 -54.329 1.00 13.35 ? 274 GLU A C 1 ATOM 2084 O O . GLU A 1 274 ? 76.120 -22.706 -55.048 1.00 12.48 ? 274 GLU A O 1 ATOM 2085 C CB . GLU A 1 274 ? 76.535 -25.503 -53.203 1.00 18.33 ? 274 GLU A CB 1 ATOM 2086 C CG . GLU A 1 274 ? 77.518 -25.793 -54.317 1.00 24.73 ? 274 GLU A CG 1 ATOM 2087 C CD . GLU A 1 274 ? 78.258 -27.097 -54.098 1.00 29.50 ? 274 GLU A CD 1 ATOM 2088 O OE1 . GLU A 1 274 ? 77.592 -28.132 -53.874 1.00 32.54 ? 274 GLU A OE1 1 ATOM 2089 O OE2 . GLU A 1 274 ? 79.507 -27.084 -54.149 1.00 32.62 ? 274 GLU A OE2 1 ATOM 2090 N N . SER A 1 275 ? 74.291 -23.928 -54.620 1.00 12.58 ? 275 SER A N 1 ATOM 2091 C CA . SER A 1 275 ? 73.618 -23.480 -55.838 1.00 12.05 ? 275 SER A CA 1 ATOM 2092 C C . SER A 1 275 ? 73.358 -21.974 -55.835 1.00 12.04 ? 275 SER A C 1 ATOM 2093 O O . SER A 1 275 ? 73.425 -21.323 -56.878 1.00 12.26 ? 275 SER A O 1 ATOM 2094 C CB . SER A 1 275 ? 72.304 -24.244 -56.034 1.00 15.86 ? 275 SER A CB 1 ATOM 2095 O OG . SER A 1 275 ? 71.450 -24.099 -54.917 1.00 20.38 ? 275 SER A OG 1 ATOM 2096 N N . TYR A 1 276 ? 73.063 -21.419 -54.665 1.00 10.66 ? 276 TYR A N 1 ATOM 2097 C CA . TYR A 1 276 ? 72.814 -19.986 -54.559 1.00 9.52 ? 276 TYR A CA 1 ATOM 2098 C C . TYR A 1 276 ? 74.091 -19.202 -54.853 1.00 8.55 ? 276 TYR A C 1 ATOM 2099 O O . TYR A 1 276 ? 74.096 -18.294 -55.684 1.00 10.02 ? 276 TYR A O 1 ATOM 2100 C CB . TYR A 1 276 ? 72.307 -19.633 -53.160 1.00 8.85 ? 276 TYR A CB 1 ATOM 2101 C CG . TYR A 1 276 ? 72.157 -18.145 -52.935 1.00 10.00 ? 276 TYR A CG 1 ATOM 2102 C CD1 . TYR A 1 276 ? 71.120 -17.428 -53.529 1.00 11.46 ? 276 TYR A CD1 1 ATOM 2103 C CD2 . TYR A 1 276 ? 73.071 -17.450 -52.146 1.00 10.96 ? 276 TYR A CD2 1 ATOM 2104 C CE1 . TYR A 1 276 ? 70.997 -16.049 -53.340 1.00 11.04 ? 276 TYR A CE1 1 ATOM 2105 C CE2 . TYR A 1 276 ? 72.960 -16.079 -51.954 1.00 12.39 ? 276 TYR A CE2 1 ATOM 2106 C CZ . TYR A 1 276 ? 71.923 -15.385 -52.551 1.00 12.39 ? 276 TYR A CZ 1 ATOM 2107 O OH . TYR A 1 276 ? 71.815 -14.029 -52.356 1.00 13.86 ? 276 TYR A OH 1 ATOM 2108 N N . LEU A 1 277 ? 75.177 -19.558 -54.174 1.00 8.14 ? 277 LEU A N 1 ATOM 2109 C CA . LEU A 1 277 ? 76.447 -18.870 -54.380 1.00 8.69 ? 277 LEU A CA 1 ATOM 2110 C C . LEU A 1 277 ? 76.904 -18.972 -55.832 1.00 9.58 ? 277 LEU A C 1 ATOM 2111 O O . LEU A 1 277 ? 77.303 -17.978 -56.434 1.00 10.44 ? 277 LEU A O 1 ATOM 2112 C CB . LEU A 1 277 ? 77.526 -19.443 -53.454 1.00 7.95 ? 277 LEU A CB 1 ATOM 2113 C CG . LEU A 1 277 ? 77.298 -19.234 -51.952 1.00 9.53 ? 277 LEU A CG 1 ATOM 2114 C CD1 . LEU A 1 277 ? 78.416 -19.908 -51.167 1.00 11.83 ? 277 LEU A CD1 1 ATOM 2115 C CD2 . LEU A 1 277 ? 77.255 -17.744 -51.641 1.00 10.38 ? 277 LEU A CD2 1 ATOM 2116 N N . SER A 1 278 ? 76.842 -20.174 -56.393 1.00 9.52 ? 278 SER A N 1 ATOM 2117 C CA . SER A 1 278 ? 77.259 -20.374 -57.777 1.00 10.31 ? 278 SER A CA 1 ATOM 2118 C C . SER A 1 278 ? 76.445 -19.523 -58.744 1.00 9.52 ? 278 SER A C 1 ATOM 2119 O O . SER A 1 278 ? 76.988 -18.990 -59.712 1.00 11.30 ? 278 SER A O 1 ATOM 2120 C CB . SER A 1 278 ? 77.136 -21.850 -58.163 1.00 12.23 ? 278 SER A CB 1 ATOM 2121 O OG A SER A 1 278 ? 78.038 -22.646 -57.414 0.50 12.79 ? 278 SER A OG 1 ATOM 2122 O OG B SER A 1 278 ? 77.574 -22.059 -59.494 0.50 12.80 ? 278 SER A OG 1 ATOM 2123 N N . SER A 1 279 ? 75.147 -19.390 -58.483 1.00 9.70 ? 279 SER A N 1 ATOM 2124 C CA . SER A 1 279 ? 74.284 -18.602 -59.362 1.00 10.79 ? 279 SER A CA 1 ATOM 2125 C C . SER A 1 279 ? 74.752 -17.158 -59.440 1.00 10.49 ? 279 SER A C 1 ATOM 2126 O O . SER A 1 279 ? 74.484 -16.464 -60.420 1.00 10.88 ? 279 SER A O 1 ATOM 2127 C CB . SER A 1 279 ? 72.834 -18.625 -58.872 1.00 10.40 ? 279 SER A CB 1 ATOM 2128 O OG . SER A 1 279 ? 72.660 -17.783 -57.742 1.00 12.58 ? 279 SER A OG 1 ATOM 2129 N N . LEU A 1 280 ? 75.452 -16.707 -58.405 1.00 9.76 ? 280 LEU A N 1 ATOM 2130 C CA . LEU A 1 280 ? 75.942 -15.335 -58.362 1.00 10.28 ? 280 LEU A CA 1 ATOM 2131 C C . LEU A 1 280 ? 77.437 -15.250 -58.650 1.00 10.50 ? 280 LEU A C 1 ATOM 2132 O O . LEU A 1 280 ? 78.035 -14.176 -58.564 1.00 11.01 ? 280 LEU A O 1 ATOM 2133 C CB . LEU A 1 280 ? 75.636 -14.715 -56.993 1.00 9.59 ? 280 LEU A CB 1 ATOM 2134 C CG . LEU A 1 280 ? 74.155 -14.609 -56.615 1.00 11.62 ? 280 LEU A CG 1 ATOM 2135 C CD1 . LEU A 1 280 ? 74.031 -14.016 -55.218 1.00 10.82 ? 280 LEU A CD1 1 ATOM 2136 C CD2 . LEU A 1 280 ? 73.420 -13.742 -57.633 1.00 11.33 ? 280 LEU A CD2 1 ATOM 2137 N N . ASN A 1 281 ? 78.033 -16.387 -58.992 1.00 10.29 ? 281 ASN A N 1 ATOM 2138 C CA . ASN A 1 281 ? 79.456 -16.451 -59.301 1.00 12.51 ? 281 ASN A CA 1 ATOM 2139 C C . ASN A 1 281 ? 80.344 -16.172 -58.095 1.00 12.41 ? 281 ASN A C 1 ATOM 2140 O O . ASN A 1 281 ? 81.459 -15.672 -58.234 1.00 13.75 ? 281 ASN A O 1 ATOM 2141 C CB . ASN A 1 281 ? 79.791 -15.484 -60.438 1.00 12.92 ? 281 ASN A CB 1 ATOM 2142 C CG . ASN A 1 281 ? 79.160 -15.901 -61.747 1.00 14.04 ? 281 ASN A CG 1 ATOM 2143 O OD1 . ASN A 1 281 ? 78.873 -15.069 -62.607 1.00 17.85 ? 281 ASN A OD1 1 ATOM 2144 N ND2 . ASN A 1 281 ? 78.949 -17.201 -61.909 1.00 13.84 ? 281 ASN A ND2 1 ATOM 2145 N N . ILE A 1 282 ? 79.834 -16.477 -56.907 1.00 10.68 ? 282 ILE A N 1 ATOM 2146 C CA . ILE A 1 282 ? 80.616 -16.308 -55.691 1.00 10.69 ? 282 ILE A CA 1 ATOM 2147 C C . ILE A 1 282 ? 81.266 -17.675 -55.464 1.00 11.18 ? 282 ILE A C 1 ATOM 2148 O O . ILE A 1 282 ? 80.573 -18.685 -55.334 1.00 11.44 ? 282 ILE A O 1 ATOM 2149 C CB . ILE A 1 282 ? 79.720 -15.954 -54.482 1.00 9.58 ? 282 ILE A CB 1 ATOM 2150 C CG1 . ILE A 1 282 ? 79.103 -14.564 -54.677 1.00 9.72 ? 282 ILE A CG1 1 ATOM 2151 C CG2 . ILE A 1 282 ? 80.541 -15.998 -53.196 1.00 10.24 ? 282 ILE A CG2 1 ATOM 2152 C CD1 . ILE A 1 282 ? 78.084 -14.184 -53.607 1.00 10.66 ? 282 ILE A CD1 1 ATOM 2153 N N . PRO A 1 283 ? 82.609 -17.731 -55.447 1.00 12.52 ? 283 PRO A N 1 ATOM 2154 C CA . PRO A 1 283 ? 83.282 -19.015 -55.235 1.00 12.28 ? 283 PRO A CA 1 ATOM 2155 C C . PRO A 1 283 ? 82.817 -19.677 -53.948 1.00 12.22 ? 283 PRO A C 1 ATOM 2156 O O . PRO A 1 283 ? 82.698 -19.021 -52.912 1.00 13.60 ? 283 PRO A O 1 ATOM 2157 C CB . PRO A 1 283 ? 84.756 -18.627 -55.182 1.00 13.19 ? 283 PRO A CB 1 ATOM 2158 C CG . PRO A 1 283 ? 84.819 -17.439 -56.086 1.00 14.92 ? 283 PRO A CG 1 ATOM 2159 C CD . PRO A 1 283 ? 83.592 -16.659 -55.675 1.00 12.75 ? 283 PRO A CD 1 ATOM 2160 N N . VAL A 1 284 ? 82.554 -20.976 -54.017 1.00 12.55 ? 284 VAL A N 1 ATOM 2161 C CA . VAL A 1 284 ? 82.101 -21.716 -52.848 1.00 12.75 ? 284 VAL A CA 1 ATOM 2162 C C . VAL A 1 284 ? 83.276 -22.201 -51.999 1.00 14.30 ? 284 VAL A C 1 ATOM 2163 O O . VAL A 1 284 ? 84.085 -23.016 -52.447 1.00 15.18 ? 284 VAL A O 1 ATOM 2164 C CB . VAL A 1 284 ? 81.254 -22.944 -53.255 1.00 12.68 ? 284 VAL A CB 1 ATOM 2165 C CG1 . VAL A 1 284 ? 80.770 -23.675 -52.016 1.00 12.49 ? 284 VAL A CG1 1 ATOM 2166 C CG2 . VAL A 1 284 ? 80.074 -22.504 -54.110 1.00 14.28 ? 284 VAL A CG2 1 ATOM 2167 N N . VAL A 1 285 ? 83.370 -21.685 -50.778 1.00 12.69 ? 285 VAL A N 1 ATOM 2168 C CA . VAL A 1 285 ? 84.426 -22.088 -49.858 1.00 12.64 ? 285 VAL A CA 1 ATOM 2169 C C . VAL A 1 285 ? 83.950 -23.362 -49.170 1.00 12.68 ? 285 VAL A C 1 ATOM 2170 O O . VAL A 1 285 ? 84.708 -24.321 -49.017 1.00 13.39 ? 285 VAL A O 1 ATOM 2171 C CB . VAL A 1 285 ? 84.705 -20.991 -48.809 1.00 12.81 ? 285 VAL A CB 1 ATOM 2172 C CG1 . VAL A 1 285 ? 85.623 -21.527 -47.715 1.00 13.82 ? 285 VAL A CG1 1 ATOM 2173 C CG2 . VAL A 1 285 ? 85.349 -19.789 -49.490 1.00 12.87 ? 285 VAL A CG2 1 ATOM 2174 N N . LEU A 1 286 ? 82.683 -23.366 -48.769 1.00 11.59 ? 286 LEU A N 1 ATOM 2175 C CA . LEU A 1 286 ? 82.076 -24.527 -48.129 1.00 11.86 ? 286 LEU A CA 1 ATOM 2176 C C . LEU A 1 286 ? 80.562 -24.455 -48.255 1.00 13.11 ? 286 LEU A C 1 ATOM 2177 O O . LEU A 1 286 ? 79.944 -23.456 -47.880 1.00 12.87 ? 286 LEU A O 1 ATOM 2178 C CB . LEU A 1 286 ? 82.456 -24.606 -46.645 1.00 12.19 ? 286 LEU A CB 1 ATOM 2179 C CG . LEU A 1 286 ? 81.886 -25.822 -45.902 1.00 13.04 ? 286 LEU A CG 1 ATOM 2180 C CD1 . LEU A 1 286 ? 82.460 -27.093 -46.507 1.00 13.84 ? 286 LEU A CD1 1 ATOM 2181 C CD2 . LEU A 1 286 ? 82.223 -25.747 -44.417 1.00 12.77 ? 286 LEU A CD2 1 ATOM 2182 N N . SER A 1 287 ? 79.969 -25.512 -48.801 1.00 12.20 ? 287 SER A N 1 ATOM 2183 C CA . SER A 1 287 ? 78.524 -25.569 -48.956 1.00 12.73 ? 287 SER A CA 1 ATOM 2184 C C . SER A 1 287 ? 77.906 -25.606 -47.563 1.00 12.28 ? 287 SER A C 1 ATOM 2185 O O . SER A 1 287 ? 78.191 -26.504 -46.772 1.00 13.71 ? 287 SER A O 1 ATOM 2186 C CB . SER A 1 287 ? 78.121 -26.819 -49.739 1.00 15.66 ? 287 SER A CB 1 ATOM 2187 O OG . SER A 1 287 ? 76.715 -26.884 -49.892 1.00 18.37 ? 287 SER A OG 1 ATOM 2188 N N . HIS A 1 288 ? 77.072 -24.614 -47.269 1.00 11.62 ? 288 HIS A N 1 ATOM 2189 C CA . HIS A 1 288 ? 76.405 -24.496 -45.974 1.00 11.49 ? 288 HIS A CA 1 ATOM 2190 C C . HIS A 1 288 ? 74.979 -24.062 -46.278 1.00 11.56 ? 288 HIS A C 1 ATOM 2191 O O . HIS A 1 288 ? 74.671 -22.871 -46.316 1.00 11.04 ? 288 HIS A O 1 ATOM 2192 C CB . HIS A 1 288 ? 77.118 -23.445 -45.119 1.00 12.70 ? 288 HIS A CB 1 ATOM 2193 C CG . HIS A 1 288 ? 77.731 -24.000 -43.871 1.00 13.78 ? 288 HIS A CG 1 ATOM 2194 N ND1 . HIS A 1 288 ? 76.978 -24.455 -42.813 1.00 15.06 ? 288 HIS A ND1 1 ATOM 2195 C CD2 . HIS A 1 288 ? 79.027 -24.182 -43.519 1.00 14.14 ? 288 HIS A CD2 1 ATOM 2196 C CE1 . HIS A 1 288 ? 77.782 -24.895 -41.859 1.00 14.58 ? 288 HIS A CE1 1 ATOM 2197 N NE2 . HIS A 1 288 ? 79.029 -24.740 -42.263 1.00 13.84 ? 288 HIS A NE2 1 ATOM 2198 N N . PRO A 1 289 ? 74.085 -25.036 -46.492 1.00 11.16 ? 289 PRO A N 1 ATOM 2199 C CA . PRO A 1 289 ? 72.678 -24.788 -46.815 1.00 11.94 ? 289 PRO A CA 1 ATOM 2200 C C . PRO A 1 289 ? 71.840 -23.879 -45.927 1.00 10.96 ? 289 PRO A C 1 ATOM 2201 O O . PRO A 1 289 ? 70.901 -23.249 -46.415 1.00 11.46 ? 289 PRO A O 1 ATOM 2202 C CB . PRO A 1 289 ? 72.093 -26.200 -46.911 1.00 13.75 ? 289 PRO A CB 1 ATOM 2203 C CG . PRO A 1 289 ? 72.941 -26.986 -45.971 1.00 14.84 ? 289 PRO A CG 1 ATOM 2204 C CD . PRO A 1 289 ? 74.325 -26.476 -46.293 1.00 13.77 ? 289 PRO A CD 1 ATOM 2205 N N . TYR A 1 290 ? 72.171 -23.784 -44.645 1.00 10.09 ? 290 TYR A N 1 ATOM 2206 C CA . TYR A 1 290 ? 71.358 -22.975 -43.749 1.00 9.98 ? 290 TYR A CA 1 ATOM 2207 C C . TYR A 1 290 ? 71.813 -21.552 -43.444 1.00 9.36 ? 290 TYR A C 1 ATOM 2208 O O . TYR A 1 290 ? 71.190 -20.871 -42.631 1.00 9.43 ? 290 TYR A O 1 ATOM 2209 C CB . TYR A 1 290 ? 71.117 -23.752 -42.452 1.00 11.11 ? 290 TYR A CB 1 ATOM 2210 C CG . TYR A 1 290 ? 70.455 -25.088 -42.713 1.00 13.57 ? 290 TYR A CG 1 ATOM 2211 C CD1 . TYR A 1 290 ? 71.102 -26.284 -42.409 1.00 14.38 ? 290 TYR A CD1 1 ATOM 2212 C CD2 . TYR A 1 290 ? 69.199 -25.154 -43.314 1.00 13.67 ? 290 TYR A CD2 1 ATOM 2213 C CE1 . TYR A 1 290 ? 70.515 -27.516 -42.703 1.00 16.65 ? 290 TYR A CE1 1 ATOM 2214 C CE2 . TYR A 1 290 ? 68.604 -26.378 -43.613 1.00 17.19 ? 290 TYR A CE2 1 ATOM 2215 C CZ . TYR A 1 290 ? 69.268 -27.553 -43.307 1.00 18.34 ? 290 TYR A CZ 1 ATOM 2216 O OH . TYR A 1 290 ? 68.692 -28.764 -43.620 1.00 20.37 ? 290 TYR A OH 1 ATOM 2217 N N . VAL A 1 291 ? 72.885 -21.094 -44.087 1.00 8.81 ? 291 VAL A N 1 ATOM 2218 C CA . VAL A 1 291 ? 73.338 -19.723 -43.867 1.00 8.03 ? 291 VAL A CA 1 ATOM 2219 C C . VAL A 1 291 ? 72.277 -18.793 -44.460 1.00 9.71 ? 291 VAL A C 1 ATOM 2220 O O . VAL A 1 291 ? 71.929 -18.905 -45.636 1.00 8.91 ? 291 VAL A O 1 ATOM 2221 C CB . VAL A 1 291 ? 74.694 -19.442 -44.562 1.00 7.17 ? 291 VAL A CB 1 ATOM 2222 C CG1 . VAL A 1 291 ? 75.025 -17.949 -44.484 1.00 6.91 ? 291 VAL A CG1 1 ATOM 2223 C CG2 . VAL A 1 291 ? 75.802 -20.246 -43.890 1.00 7.73 ? 291 VAL A CG2 1 ATOM 2224 N N . GLY A 1 292 ? 71.756 -17.885 -43.640 1.00 8.64 ? 292 GLY A N 1 ATOM 2225 C CA . GLY A 1 292 ? 70.738 -16.967 -44.117 1.00 9.56 ? 292 GLY A CA 1 ATOM 2226 C C . GLY A 1 292 ? 69.338 -17.539 -44.005 1.00 10.20 ? 292 GLY A C 1 ATOM 2227 O O . GLY A 1 292 ? 68.367 -16.895 -44.389 1.00 10.47 ? 292 GLY A O 1 ATOM 2228 N N . GLN A 1 293 ? 69.229 -18.759 -43.490 1.00 8.84 ? 293 GLN A N 1 ATOM 2229 C CA . GLN A 1 293 ? 67.925 -19.390 -43.335 1.00 8.33 ? 293 GLN A CA 1 ATOM 2230 C C . GLN A 1 293 ? 67.438 -19.247 -41.903 1.00 9.00 ? 293 GLN A C 1 ATOM 2231 O O . GLN A 1 293 ? 68.229 -19.020 -40.988 1.00 8.97 ? 293 GLN A O 1 ATOM 2232 C CB . GLN A 1 293 ? 68.001 -20.875 -43.707 1.00 11.30 ? 293 GLN A CB 1 ATOM 2233 C CG . GLN A 1 293 ? 68.426 -21.127 -45.147 1.00 14.38 ? 293 GLN A CG 1 ATOM 2234 C CD . GLN A 1 293 ? 67.493 -20.478 -46.151 1.00 15.83 ? 293 GLN A CD 1 ATOM 2235 O OE1 . GLN A 1 293 ? 66.302 -20.781 -46.193 1.00 20.42 ? 293 GLN A OE1 1 ATOM 2236 N NE2 . GLN A 1 293 ? 68.034 -19.580 -46.967 1.00 19.01 ? 293 GLN A NE2 1 ATOM 2237 N N . PHE A 1 294 ? 66.128 -19.379 -41.722 1.00 9.52 ? 294 PHE A N 1 ATOM 2238 C CA . PHE A 1 294 ? 65.509 -19.288 -40.407 1.00 9.58 ? 294 PHE A CA 1 ATOM 2239 C C . PHE A 1 294 ? 65.666 -17.913 -39.760 1.00 9.16 ? 294 PHE A C 1 ATOM 2240 O O . PHE A 1 294 ? 66.198 -17.786 -38.656 1.00 10.55 ? 294 PHE A O 1 ATOM 2241 C CB . PHE A 1 294 ? 66.080 -20.376 -39.492 1.00 11.46 ? 294 PHE A CB 1 ATOM 2242 C CG . PHE A 1 294 ? 65.993 -21.757 -40.079 1.00 13.76 ? 294 PHE A CG 1 ATOM 2243 C CD1 . PHE A 1 294 ? 67.141 -22.518 -40.273 1.00 15.74 ? 294 PHE A CD1 1 ATOM 2244 C CD2 . PHE A 1 294 ? 64.765 -22.283 -40.471 1.00 17.75 ? 294 PHE A CD2 1 ATOM 2245 C CE1 . PHE A 1 294 ? 67.071 -23.782 -40.855 1.00 17.91 ? 294 PHE A CE1 1 ATOM 2246 C CE2 . PHE A 1 294 ? 64.684 -23.549 -41.054 1.00 18.65 ? 294 PHE A CE2 1 ATOM 2247 C CZ . PHE A 1 294 ? 65.840 -24.299 -41.247 1.00 19.09 ? 294 PHE A CZ 1 ATOM 2248 N N . LEU A 1 295 ? 65.204 -16.888 -40.471 1.00 8.95 ? 295 LEU A N 1 ATOM 2249 C CA . LEU A 1 295 ? 65.232 -15.508 -39.980 1.00 8.05 ? 295 LEU A CA 1 ATOM 2250 C C . LEU A 1 295 ? 63.869 -15.258 -39.337 1.00 7.79 ? 295 LEU A C 1 ATOM 2251 O O . LEU A 1 295 ? 62.840 -15.343 -40.012 1.00 8.83 ? 295 LEU A O 1 ATOM 2252 C CB . LEU A 1 295 ? 65.437 -14.526 -41.138 1.00 10.64 ? 295 LEU A CB 1 ATOM 2253 C CG A LEU A 1 295 ? 66.852 -14.122 -41.562 0.50 11.50 ? 295 LEU A CG 1 ATOM 2254 C CG B LEU A 1 295 ? 65.706 -13.085 -40.714 0.50 11.31 ? 295 LEU A CG 1 ATOM 2255 C CD1 A LEU A 1 295 ? 67.457 -13.223 -40.507 0.50 9.18 ? 295 LEU A CD1 1 ATOM 2256 C CD1 B LEU A 1 295 ? 67.045 -12.928 -40.010 0.50 8.89 ? 295 LEU A CD1 1 ATOM 2257 C CD2 A LEU A 1 295 ? 67.709 -15.355 -41.790 0.50 10.01 ? 295 LEU A CD2 1 ATOM 2258 C CD2 B LEU A 1 295 ? 65.632 -12.175 -41.931 0.50 9.86 ? 295 LEU A CD2 1 ATOM 2259 N N . HIS A 1 296 ? 63.869 -14.938 -38.044 1.00 7.52 ? 296 HIS A N 1 ATOM 2260 C CA . HIS A 1 296 ? 62.637 -14.707 -37.287 1.00 8.03 ? 296 HIS A CA 1 ATOM 2261 C C . HIS A 1 296 ? 62.492 -13.270 -36.792 1.00 8.76 ? 296 HIS A C 1 ATOM 2262 O O . HIS A 1 296 ? 63.456 -12.682 -36.301 1.00 10.42 ? 296 HIS A O 1 ATOM 2263 C CB . HIS A 1 296 ? 62.595 -15.598 -36.036 1.00 8.25 ? 296 HIS A CB 1 ATOM 2264 C CG . HIS A 1 296 ? 62.643 -17.068 -36.312 1.00 8.66 ? 296 HIS A CG 1 ATOM 2265 N ND1 . HIS A 1 296 ? 61.589 -17.912 -36.020 1.00 8.71 ? 296 HIS A ND1 1 ATOM 2266 C CD2 . HIS A 1 296 ? 63.630 -17.858 -36.794 1.00 8.12 ? 296 HIS A CD2 1 ATOM 2267 C CE1 . HIS A 1 296 ? 61.929 -19.153 -36.308 1.00 9.26 ? 296 HIS A CE1 1 ATOM 2268 N NE2 . HIS A 1 296 ? 63.165 -19.149 -36.782 1.00 10.79 ? 296 HIS A NE2 1 ATOM 2269 N N . ASP A 1 297 ? 61.293 -12.705 -36.910 1.00 6.43 ? 297 ASP A N 1 ATOM 2270 C CA . ASP A 1 297 ? 61.054 -11.367 -36.380 1.00 5.84 ? 297 ASP A CA 1 ATOM 2271 C C . ASP A 1 297 ? 59.729 -11.366 -35.631 1.00 4.91 ? 297 ASP A C 1 ATOM 2272 O O . ASP A 1 297 ? 58.663 -11.483 -36.234 1.00 7.40 ? 297 ASP A O 1 ATOM 2273 C CB . ASP A 1 297 ? 61.025 -10.297 -37.476 1.00 6.12 ? 297 ASP A CB 1 ATOM 2274 C CG . ASP A 1 297 ? 61.009 -8.889 -36.898 1.00 7.81 ? 297 ASP A CG 1 ATOM 2275 O OD1 . ASP A 1 297 ? 61.755 -8.643 -35.920 1.00 8.56 ? 297 ASP A OD1 1 ATOM 2276 O OD2 . ASP A 1 297 ? 60.263 -8.028 -37.415 1.00 9.09 ? 297 ASP A OD2 1 ATOM 2277 N N . ASN A 1 298 ? 59.797 -11.250 -34.308 1.00 5.55 ? 298 ASN A N 1 ATOM 2278 C CA . ASN A 1 298 ? 58.584 -11.234 -33.501 1.00 4.39 ? 298 ASN A CA 1 ATOM 2279 C C . ASN A 1 298 ? 57.725 -10.052 -33.905 1.00 5.92 ? 298 ASN A C 1 ATOM 2280 O O . ASN A 1 298 ? 58.202 -8.921 -33.961 1.00 7.59 ? 298 ASN A O 1 ATOM 2281 C CB . ASN A 1 298 ? 58.912 -11.111 -32.011 1.00 6.38 ? 298 ASN A CB 1 ATOM 2282 C CG . ASN A 1 298 ? 59.856 -12.188 -31.535 1.00 6.99 ? 298 ASN A CG 1 ATOM 2283 O OD1 . ASN A 1 298 ? 61.045 -12.169 -31.853 1.00 9.21 ? 298 ASN A OD1 1 ATOM 2284 N ND2 . ASN A 1 298 ? 59.332 -13.136 -30.768 1.00 6.97 ? 298 ASN A ND2 1 ATOM 2285 N N . PRO A 1 299 ? 56.445 -10.298 -34.206 1.00 6.83 ? 299 PRO A N 1 ATOM 2286 C CA . PRO A 1 299 ? 55.580 -9.186 -34.597 1.00 6.95 ? 299 PRO A CA 1 ATOM 2287 C C . PRO A 1 299 ? 55.156 -8.314 -33.424 1.00 7.97 ? 299 PRO A C 1 ATOM 2288 O O . PRO A 1 299 ? 55.013 -8.783 -32.293 1.00 8.71 ? 299 PRO A O 1 ATOM 2289 C CB . PRO A 1 299 ? 54.391 -9.887 -35.254 1.00 7.29 ? 299 PRO A CB 1 ATOM 2290 C CG . PRO A 1 299 ? 54.308 -11.182 -34.504 1.00 8.40 ? 299 PRO A CG 1 ATOM 2291 C CD . PRO A 1 299 ? 55.762 -11.593 -34.389 1.00 6.73 ? 299 PRO A CD 1 ATOM 2292 N N . ARG A 1 300 ? 54.982 -7.030 -33.707 1.00 6.78 ? 300 ARG A N 1 ATOM 2293 C CA . ARG A 1 300 ? 54.530 -6.079 -32.711 1.00 7.16 ? 300 ARG A CA 1 ATOM 2294 C C . ARG A 1 300 ? 53.186 -5.554 -33.174 1.00 7.28 ? 300 ARG A C 1 ATOM 2295 O O . ARG A 1 300 ? 53.038 -5.123 -34.314 1.00 8.39 ? 300 ARG A O 1 ATOM 2296 C CB . ARG A 1 300 ? 55.497 -4.895 -32.578 1.00 8.40 ? 300 ARG A CB 1 ATOM 2297 C CG . ARG A 1 300 ? 54.941 -3.728 -31.736 1.00 8.13 ? 300 ARG A CG 1 ATOM 2298 C CD . ARG A 1 300 ? 56.030 -2.722 -31.365 1.00 10.54 ? 300 ARG A CD 1 ATOM 2299 N NE . ARG A 1 300 ? 56.774 -2.276 -32.540 1.00 10.45 ? 300 ARG A NE 1 ATOM 2300 C CZ . ARG A 1 300 ? 56.580 -1.122 -33.172 1.00 8.73 ? 300 ARG A CZ 1 ATOM 2301 N NH1 . ARG A 1 300 ? 55.665 -0.262 -32.743 1.00 9.83 ? 300 ARG A NH1 1 ATOM 2302 N NH2 . ARG A 1 300 ? 57.282 -0.845 -34.260 1.00 9.31 ? 300 ARG A NH2 1 ATOM 2303 N N . ASN A 1 301 ? 52.193 -5.635 -32.301 1.00 7.30 ? 301 ASN A N 1 ATOM 2304 C CA . ASN A 1 301 ? 50.887 -5.087 -32.611 1.00 7.37 ? 301 ASN A CA 1 ATOM 2305 C C . ASN A 1 301 ? 50.657 -4.114 -31.470 1.00 8.37 ? 301 ASN A C 1 ATOM 2306 O O . ASN A 1 301 ? 51.194 -4.298 -30.370 1.00 8.19 ? 301 ASN A O 1 ATOM 2307 C CB . ASN A 1 301 ? 49.831 -6.184 -32.721 1.00 8.79 ? 301 ASN A CB 1 ATOM 2308 C CG . ASN A 1 301 ? 50.008 -7.013 -33.990 1.00 8.75 ? 301 ASN A CG 1 ATOM 2309 O OD1 . ASN A 1 301 ? 50.789 -7.963 -34.026 1.00 10.82 ? 301 ASN A OD1 1 ATOM 2310 N ND2 . ASN A 1 301 ? 49.298 -6.632 -35.046 1.00 11.26 ? 301 ASN A ND2 1 ATOM 2311 N N . PHE A 1 302 ? 49.865 -3.081 -31.714 1.00 7.61 ? 302 PHE A N 1 ATOM 2312 C CA . PHE A 1 302 ? 49.735 -2.044 -30.706 1.00 8.87 ? 302 PHE A CA 1 ATOM 2313 C C . PHE A 1 302 ? 48.506 -1.159 -30.816 1.00 8.08 ? 302 PHE A C 1 ATOM 2314 O O . PHE A 1 302 ? 47.751 -1.224 -31.784 1.00 8.49 ? 302 PHE A O 1 ATOM 2315 C CB . PHE A 1 302 ? 50.956 -1.150 -30.854 1.00 8.74 ? 302 PHE A CB 1 ATOM 2316 C CG . PHE A 1 302 ? 51.095 -0.580 -32.248 1.00 9.61 ? 302 PHE A CG 1 ATOM 2317 C CD1 . PHE A 1 302 ? 50.362 0.540 -32.633 1.00 7.68 ? 302 PHE A CD1 1 ATOM 2318 C CD2 . PHE A 1 302 ? 51.887 -1.217 -33.199 1.00 9.57 ? 302 PHE A CD2 1 ATOM 2319 C CE1 . PHE A 1 302 ? 50.413 1.015 -33.950 1.00 7.56 ? 302 PHE A CE1 1 ATOM 2320 C CE2 . PHE A 1 302 ? 51.945 -0.753 -34.514 1.00 10.13 ? 302 PHE A CE2 1 ATOM 2321 C CZ . PHE A 1 302 ? 51.204 0.366 -34.890 1.00 9.32 ? 302 PHE A CZ 1 ATOM 2322 N N . ILE A 1 303 ? 48.345 -0.313 -29.802 1.00 8.52 ? 303 ILE A N 1 ATOM 2323 C CA . ILE A 1 303 ? 47.278 0.674 -29.759 1.00 8.49 ? 303 ILE A CA 1 ATOM 2324 C C . ILE A 1 303 ? 47.881 1.963 -29.209 1.00 8.46 ? 303 ILE A C 1 ATOM 2325 O O . ILE A 1 303 ? 48.532 1.959 -28.157 1.00 9.18 ? 303 ILE A O 1 ATOM 2326 C CB . ILE A 1 303 ? 46.104 0.250 -28.844 1.00 8.43 ? 303 ILE A CB 1 ATOM 2327 C CG1 . ILE A 1 303 ? 45.352 -0.937 -29.454 1.00 7.43 ? 303 ILE A CG1 1 ATOM 2328 C CG2 . ILE A 1 303 ? 45.150 1.431 -28.649 1.00 9.06 ? 303 ILE A CG2 1 ATOM 2329 C CD1 . ILE A 1 303 ? 44.645 -0.624 -30.772 1.00 8.60 ? 303 ILE A CD1 1 ATOM 2330 N N . ASN A 1 304 ? 47.688 3.057 -29.940 1.00 8.57 ? 304 ASN A N 1 ATOM 2331 C CA . ASN A 1 304 ? 48.179 4.362 -29.515 1.00 8.72 ? 304 ASN A CA 1 ATOM 2332 C C . ASN A 1 304 ? 46.988 5.183 -29.037 1.00 9.64 ? 304 ASN A C 1 ATOM 2333 O O . ASN A 1 304 ? 46.031 5.377 -29.789 1.00 10.36 ? 304 ASN A O 1 ATOM 2334 C CB . ASN A 1 304 ? 48.832 5.118 -30.681 1.00 11.44 ? 304 ASN A CB 1 ATOM 2335 C CG . ASN A 1 304 ? 50.009 4.382 -31.279 1.00 12.44 ? 304 ASN A CG 1 ATOM 2336 O OD1 . ASN A 1 304 ? 50.980 4.074 -30.590 1.00 12.94 ? 304 ASN A OD1 1 ATOM 2337 N ND2 . ASN A 1 304 ? 49.933 4.105 -32.576 1.00 15.67 ? 304 ASN A ND2 1 ATOM 2338 N N . ILE A 1 305 ? 47.026 5.644 -27.791 1.00 8.84 ? 305 ILE A N 1 ATOM 2339 C CA . ILE A 1 305 ? 45.946 6.482 -27.288 1.00 9.06 ? 305 ILE A CA 1 ATOM 2340 C C . ILE A 1 305 ? 46.460 7.907 -27.112 1.00 9.55 ? 305 ILE A C 1 ATOM 2341 O O . ILE A 1 305 ? 47.630 8.126 -26.787 1.00 8.82 ? 305 ILE A O 1 ATOM 2342 C CB . ILE A 1 305 ? 45.371 5.977 -25.935 1.00 7.97 ? 305 ILE A CB 1 ATOM 2343 C CG1 . ILE A 1 305 ? 46.441 6.014 -24.842 1.00 9.01 ? 305 ILE A CG1 1 ATOM 2344 C CG2 . ILE A 1 305 ? 44.806 4.576 -26.107 1.00 8.29 ? 305 ILE A CG2 1 ATOM 2345 C CD1 . ILE A 1 305 ? 45.892 5.733 -23.446 1.00 12.29 ? 305 ILE A CD1 1 ATOM 2346 N N . LEU A 1 306 ? 45.574 8.866 -27.353 1.00 10.14 ? 306 LEU A N 1 ATOM 2347 C CA . LEU A 1 306 ? 45.881 10.287 -27.225 1.00 10.59 ? 306 LEU A CA 1 ATOM 2348 C C . LEU A 1 306 ? 45.024 10.834 -26.089 1.00 10.28 ? 306 LEU A C 1 ATOM 2349 O O . LEU A 1 306 ? 43.878 11.221 -26.302 1.00 12.07 ? 306 LEU A O 1 ATOM 2350 C CB . LEU A 1 306 ? 45.539 11.011 -28.527 1.00 10.89 ? 306 LEU A CB 1 ATOM 2351 C CG . LEU A 1 306 ? 46.366 10.603 -29.748 1.00 10.64 ? 306 LEU A CG 1 ATOM 2352 C CD1 . LEU A 1 306 ? 45.623 10.963 -31.025 1.00 12.86 ? 306 LEU A CD1 1 ATOM 2353 C CD2 . LEU A 1 306 ? 47.719 11.284 -29.687 1.00 14.29 ? 306 LEU A CD2 1 ATOM 2354 N N . PRO A 1 307 ? 45.568 10.859 -24.863 1.00 10.86 ? 307 PRO A N 1 ATOM 2355 C CA . PRO A 1 307 ? 44.852 11.353 -23.681 1.00 12.24 ? 307 PRO A CA 1 ATOM 2356 C C . PRO A 1 307 ? 44.424 12.813 -23.789 1.00 14.47 ? 307 PRO A C 1 ATOM 2357 O O . PRO A 1 307 ? 45.151 13.641 -24.337 1.00 13.39 ? 307 PRO A O 1 ATOM 2358 C CB . PRO A 1 307 ? 45.860 11.141 -22.552 1.00 12.79 ? 307 PRO A CB 1 ATOM 2359 C CG . PRO A 1 307 ? 46.672 9.974 -23.032 1.00 13.57 ? 307 PRO A CG 1 ATOM 2360 C CD . PRO A 1 307 ? 46.887 10.324 -24.483 1.00 11.72 ? 307 PRO A CD 1 ATOM 2361 N N . PRO A 1 308 ? 43.230 13.143 -23.266 1.00 14.54 ? 308 PRO A N 1 ATOM 2362 C CA . PRO A 1 308 ? 42.735 14.522 -23.315 1.00 16.45 ? 308 PRO A CA 1 ATOM 2363 C C . PRO A 1 308 ? 43.598 15.396 -22.409 1.00 17.16 ? 308 PRO A C 1 ATOM 2364 O O . PRO A 1 308 ? 43.688 16.613 -22.582 1.00 17.95 ? 308 PRO A O 1 ATOM 2365 C CB . PRO A 1 308 ? 41.297 14.386 -22.819 1.00 16.17 ? 308 PRO A CB 1 ATOM 2366 C CG . PRO A 1 308 ? 41.384 13.245 -21.854 1.00 16.47 ? 308 PRO A CG 1 ATOM 2367 C CD . PRO A 1 308 ? 42.255 12.257 -22.603 1.00 15.31 ? 308 PRO A CD 1 ATOM 2368 N N . ASN A 1 309 ? 44.231 14.757 -21.433 1.00 19.33 ? 309 ASN A N 1 ATOM 2369 C CA . ASN A 1 309 ? 45.118 15.451 -20.515 1.00 20.87 ? 309 ASN A CA 1 ATOM 2370 C C . ASN A 1 309 ? 46.522 14.926 -20.769 1.00 21.71 ? 309 ASN A C 1 ATOM 2371 O O . ASN A 1 309 ? 46.768 13.721 -20.715 1.00 22.72 ? 309 ASN A O 1 ATOM 2372 C CB . ASN A 1 309 ? 44.701 15.201 -19.067 1.00 23.53 ? 309 ASN A CB 1 ATOM 2373 C CG . ASN A 1 309 ? 43.392 15.874 -18.722 1.00 24.96 ? 309 ASN A CG 1 ATOM 2374 O OD1 . ASN A 1 309 ? 43.246 17.086 -18.886 1.00 27.31 ? 309 ASN A OD1 1 ATOM 2375 N ND2 . ASN A 1 309 ? 42.431 15.095 -18.241 1.00 26.94 ? 309 ASN A ND2 1 ATOM 2376 N N . PRO A 1 310 ? 47.463 15.831 -21.056 1.00 19.58 ? 310 PRO A N 1 ATOM 2377 C CA . PRO A 1 310 ? 48.857 15.481 -21.332 1.00 19.10 ? 310 PRO A CA 1 ATOM 2378 C C . PRO A 1 310 ? 49.494 14.522 -20.334 1.00 18.31 ? 310 PRO A C 1 ATOM 2379 O O . PRO A 1 310 ? 49.221 14.584 -19.136 1.00 17.76 ? 310 PRO A O 1 ATOM 2380 C CB . PRO A 1 310 ? 49.556 16.836 -21.334 1.00 20.42 ? 310 PRO A CB 1 ATOM 2381 C CG . PRO A 1 310 ? 48.486 17.763 -21.824 1.00 20.34 ? 310 PRO A CG 1 ATOM 2382 C CD . PRO A 1 310 ? 47.281 17.295 -21.059 1.00 19.95 ? 310 PRO A CD 1 ATOM 2383 N N . ILE A 1 311 ? 50.332 13.625 -20.846 1.00 16.68 ? 311 ILE A N 1 ATOM 2384 C CA . ILE A 1 311 ? 51.064 12.688 -20.006 1.00 15.03 ? 311 ILE A CA 1 ATOM 2385 C C . ILE A 1 311 ? 52.538 12.933 -20.304 1.00 14.82 ? 311 ILE A C 1 ATOM 2386 O O . ILE A 1 311 ? 52.887 13.410 -21.388 1.00 15.21 ? 311 ILE A O 1 ATOM 2387 C CB . ILE A 1 311 ? 50.699 11.208 -20.300 1.00 14.58 ? 311 ILE A CB 1 ATOM 2388 C CG1 . ILE A 1 311 ? 50.902 10.885 -21.780 1.00 14.28 ? 311 ILE A CG1 1 ATOM 2389 C CG2 . ILE A 1 311 ? 49.265 10.938 -19.878 1.00 14.72 ? 311 ILE A CG2 1 ATOM 2390 C CD1 . ILE A 1 311 ? 50.678 9.416 -22.107 1.00 14.82 ? 311 ILE A CD1 1 ATOM 2391 N N . GLU A 1 312 ? 53.401 12.622 -19.346 1.00 14.48 ? 312 GLU A N 1 ATOM 2392 C CA . GLU A 1 312 ? 54.828 12.854 -19.524 1.00 15.05 ? 312 GLU A CA 1 ATOM 2393 C C . GLU A 1 312 ? 55.549 11.685 -20.188 1.00 15.41 ? 312 GLU A C 1 ATOM 2394 O O . GLU A 1 312 ? 55.160 10.527 -20.021 1.00 14.10 ? 312 GLU A O 1 ATOM 2395 C CB . GLU A 1 312 ? 55.473 13.173 -18.170 1.00 17.85 ? 312 GLU A CB 1 ATOM 2396 C CG . GLU A 1 312 ? 55.864 11.973 -17.302 1.00 19.91 ? 312 GLU A CG 1 ATOM 2397 C CD . GLU A 1 312 ? 54.715 11.028 -16.976 1.00 21.04 ? 312 GLU A CD 1 ATOM 2398 O OE1 . GLU A 1 312 ? 53.537 11.455 -16.988 1.00 22.80 ? 312 GLU A OE1 1 ATOM 2399 O OE2 . GLU A 1 312 ? 55.002 9.848 -16.682 1.00 18.29 ? 312 GLU A OE2 1 ATOM 2400 N N . PRO A 1 313 ? 56.601 11.979 -20.971 1.00 14.03 ? 313 PRO A N 1 ATOM 2401 C CA . PRO A 1 313 ? 57.353 10.916 -21.643 1.00 13.71 ? 313 PRO A CA 1 ATOM 2402 C C . PRO A 1 313 ? 58.086 10.051 -20.623 1.00 13.06 ? 313 PRO A C 1 ATOM 2403 O O . PRO A 1 313 ? 58.558 10.543 -19.598 1.00 13.01 ? 313 PRO A O 1 ATOM 2404 C CB . PRO A 1 313 ? 58.303 11.689 -22.558 1.00 15.29 ? 313 PRO A CB 1 ATOM 2405 C CG . PRO A 1 313 ? 58.524 12.971 -21.811 1.00 16.96 ? 313 PRO A CG 1 ATOM 2406 C CD . PRO A 1 313 ? 57.136 13.306 -21.325 1.00 15.22 ? 313 PRO A CD 1 ATOM 2407 N N . THR A 1 314 ? 58.179 8.758 -20.908 1.00 11.63 ? 314 THR A N 1 ATOM 2408 C CA . THR A 1 314 ? 58.834 7.832 -19.995 1.00 11.79 ? 314 THR A CA 1 ATOM 2409 C C . THR A 1 314 ? 59.644 6.794 -20.746 1.00 11.17 ? 314 THR A C 1 ATOM 2410 O O . THR A 1 314 ? 59.469 6.605 -21.950 1.00 12.13 ? 314 THR A O 1 ATOM 2411 C CB . THR A 1 314 ? 57.803 7.053 -19.161 1.00 12.09 ? 314 THR A CB 1 ATOM 2412 O OG1 . THR A 1 314 ? 56.892 6.385 -20.045 1.00 10.85 ? 314 THR A OG1 1 ATOM 2413 C CG2 . THR A 1 314 ? 57.024 7.986 -18.253 1.00 11.19 ? 314 THR A CG2 1 ATOM 2414 N N . ILE A 1 315 ? 60.538 6.129 -20.024 1.00 10.61 ? 315 ILE A N 1 ATOM 2415 C CA . ILE A 1 315 ? 61.318 5.049 -20.611 1.00 11.30 ? 315 ILE A CA 1 ATOM 2416 C C . ILE A 1 315 ? 60.589 3.784 -20.158 1.00 10.43 ? 315 ILE A C 1 ATOM 2417 O O . ILE A 1 315 ? 60.049 3.732 -19.052 1.00 9.92 ? 315 ILE A O 1 ATOM 2418 C CB . ILE A 1 315 ? 62.776 5.019 -20.093 1.00 14.65 ? 315 ILE A CB 1 ATOM 2419 C CG1 . ILE A 1 315 ? 62.797 4.910 -18.570 1.00 16.29 ? 315 ILE A CG1 1 ATOM 2420 C CG2 . ILE A 1 315 ? 63.517 6.263 -20.562 1.00 15.59 ? 315 ILE A CG2 1 ATOM 2421 C CD1 . ILE A 1 315 ? 64.187 4.684 -17.994 1.00 17.88 ? 315 ILE A CD1 1 ATOM 2422 N N . VAL A 1 316 ? 60.549 2.773 -21.014 1.00 9.14 ? 316 VAL A N 1 ATOM 2423 C CA . VAL A 1 316 ? 59.861 1.534 -20.675 1.00 8.53 ? 316 VAL A CA 1 ATOM 2424 C C . VAL A 1 316 ? 60.545 0.793 -19.533 1.00 7.62 ? 316 VAL A C 1 ATOM 2425 O O . VAL A 1 316 ? 61.741 0.503 -19.602 1.00 8.78 ? 316 VAL A O 1 ATOM 2426 C CB . VAL A 1 316 ? 59.782 0.598 -21.895 1.00 8.82 ? 316 VAL A CB 1 ATOM 2427 C CG1 . VAL A 1 316 ? 59.168 -0.737 -21.490 1.00 10.60 ? 316 VAL A CG1 1 ATOM 2428 C CG2 . VAL A 1 316 ? 58.947 1.250 -22.990 1.00 13.10 ? 316 VAL A CG2 1 ATOM 2429 N N . THR A 1 317 ? 59.783 0.497 -18.484 1.00 7.36 ? 317 THR A N 1 ATOM 2430 C CA . THR A 1 317 ? 60.316 -0.233 -17.334 1.00 8.60 ? 317 THR A CA 1 ATOM 2431 C C . THR A 1 317 ? 59.341 -1.297 -16.824 1.00 9.13 ? 317 THR A C 1 ATOM 2432 O O . THR A 1 317 ? 59.760 -2.300 -16.239 1.00 8.26 ? 317 THR A O 1 ATOM 2433 C CB . THR A 1 317 ? 60.655 0.712 -16.161 1.00 8.60 ? 317 THR A CB 1 ATOM 2434 O OG1 . THR A 1 317 ? 59.452 1.306 -15.658 1.00 9.26 ? 317 THR A OG1 1 ATOM 2435 C CG2 . THR A 1 317 ? 61.617 1.805 -16.614 1.00 8.73 ? 317 THR A CG2 1 ATOM 2436 N N . VAL A 1 318 ? 58.049 -1.082 -17.049 1.00 8.75 ? 318 VAL A N 1 ATOM 2437 C CA . VAL A 1 318 ? 57.032 -2.030 -16.599 1.00 9.09 ? 318 VAL A CA 1 ATOM 2438 C C . VAL A 1 318 ? 56.660 -3.026 -17.695 1.00 8.66 ? 318 VAL A C 1 ATOM 2439 O O . VAL A 1 318 ? 56.253 -2.643 -18.794 1.00 9.03 ? 318 VAL A O 1 ATOM 2440 C CB . VAL A 1 318 ? 55.760 -1.286 -16.113 1.00 8.54 ? 318 VAL A CB 1 ATOM 2441 C CG1 . VAL A 1 318 ? 54.620 -2.273 -15.882 1.00 9.99 ? 318 VAL A CG1 1 ATOM 2442 C CG2 . VAL A 1 318 ? 56.071 -0.543 -14.824 1.00 9.05 ? 318 VAL A CG2 1 ATOM 2443 N N . LEU A 1 319 ? 56.807 -4.310 -17.386 1.00 8.36 ? 319 LEU A N 1 ATOM 2444 C CA . LEU A 1 319 ? 56.492 -5.356 -18.346 1.00 7.06 ? 319 LEU A CA 1 ATOM 2445 C C . LEU A 1 319 ? 55.354 -6.257 -17.876 1.00 7.04 ? 319 LEU A C 1 ATOM 2446 O O . LEU A 1 319 ? 55.301 -6.645 -16.706 1.00 8.79 ? 319 LEU A O 1 ATOM 2447 C CB . LEU A 1 319 ? 57.733 -6.212 -18.616 1.00 6.50 ? 319 LEU A CB 1 ATOM 2448 C CG . LEU A 1 319 ? 58.996 -5.458 -19.035 1.00 7.43 ? 319 LEU A CG 1 ATOM 2449 C CD1 . LEU A 1 319 ? 60.084 -6.464 -19.377 1.00 7.02 ? 319 LEU A CD1 1 ATOM 2450 C CD2 . LEU A 1 319 ? 58.692 -4.566 -20.242 1.00 8.60 ? 319 LEU A CD2 1 ATOM 2451 N N . GLY A 1 320 ? 54.448 -6.569 -18.802 1.00 7.89 ? 320 GLY A N 1 ATOM 2452 C CA . GLY A 1 320 ? 53.320 -7.442 -18.524 1.00 7.93 ? 320 GLY A CA 1 ATOM 2453 C C . GLY A 1 320 ? 53.585 -8.693 -19.338 1.00 8.81 ? 320 GLY A C 1 ATOM 2454 O O . GLY A 1 320 ? 53.336 -8.732 -20.548 1.00 7.92 ? 320 GLY A O 1 ATOM 2455 N N . ILE A 1 321 ? 54.088 -9.723 -18.669 1.00 7.39 ? 321 ILE A N 1 ATOM 2456 C CA . ILE A 1 321 ? 54.468 -10.964 -19.331 1.00 8.12 ? 321 ILE A CA 1 ATOM 2457 C C . ILE A 1 321 ? 53.482 -12.123 -19.271 1.00 8.48 ? 321 ILE A C 1 ATOM 2458 O O . ILE A 1 321 ? 53.083 -12.561 -18.199 1.00 9.13 ? 321 ILE A O 1 ATOM 2459 C CB . ILE A 1 321 ? 55.827 -11.467 -18.763 1.00 8.02 ? 321 ILE A CB 1 ATOM 2460 C CG1 . ILE A 1 321 ? 56.884 -10.364 -18.891 1.00 8.30 ? 321 ILE A CG1 1 ATOM 2461 C CG2 . ILE A 1 321 ? 56.273 -12.735 -19.483 1.00 7.37 ? 321 ILE A CG2 1 ATOM 2462 C CD1 . ILE A 1 321 ? 57.167 -9.930 -20.325 1.00 8.17 ? 321 ILE A CD1 1 ATOM 2463 N N . SER A 1 322 ? 53.088 -12.608 -20.442 1.00 8.66 ? 322 SER A N 1 ATOM 2464 C CA . SER A 1 322 ? 52.212 -13.767 -20.531 1.00 11.25 ? 322 SER A CA 1 ATOM 2465 C C . SER A 1 322 ? 53.075 -14.820 -21.219 1.00 10.54 ? 322 SER A C 1 ATOM 2466 O O . SER A 1 322 ? 54.141 -14.500 -21.748 1.00 11.37 ? 322 SER A O 1 ATOM 2467 C CB . SER A 1 322 ? 50.964 -13.446 -21.359 1.00 12.72 ? 322 SER A CB 1 ATOM 2468 O OG . SER A 1 322 ? 50.132 -12.520 -20.674 1.00 17.32 ? 322 SER A OG 1 ATOM 2469 N N . ASN A 1 323 ? 52.644 -16.075 -21.218 1.00 12.98 ? 323 ASN A N 1 ATOM 2470 C CA . ASN A 1 323 ? 53.450 -17.114 -21.846 1.00 13.26 ? 323 ASN A CA 1 ATOM 2471 C C . ASN A 1 323 ? 53.568 -16.989 -23.360 1.00 12.53 ? 323 ASN A C 1 ATOM 2472 O O . ASN A 1 323 ? 54.605 -17.317 -23.935 1.00 14.09 ? 323 ASN A O 1 ATOM 2473 C CB . ASN A 1 323 ? 52.904 -18.503 -21.502 1.00 16.23 ? 323 ASN A CB 1 ATOM 2474 C CG . ASN A 1 323 ? 53.146 -18.879 -20.054 1.00 20.34 ? 323 ASN A CG 1 ATOM 2475 O OD1 . ASN A 1 323 ? 52.229 -18.865 -19.235 1.00 23.95 ? 323 ASN A OD1 1 ATOM 2476 N ND2 . ASN A 1 323 ? 54.390 -19.208 -19.731 1.00 21.54 ? 323 ASN A ND2 1 ATOM 2477 N N . ASP A 1 324 ? 52.515 -16.501 -24.008 1.00 10.66 ? 324 ASP A N 1 ATOM 2478 C CA . ASP A 1 324 ? 52.528 -16.391 -25.461 1.00 10.21 ? 324 ASP A CA 1 ATOM 2479 C C . ASP A 1 324 ? 52.751 -14.996 -26.040 1.00 8.66 ? 324 ASP A C 1 ATOM 2480 O O . ASP A 1 324 ? 52.924 -14.850 -27.253 1.00 9.23 ? 324 ASP A O 1 ATOM 2481 C CB . ASP A 1 324 ? 51.230 -16.971 -26.025 1.00 14.11 ? 324 ASP A CB 1 ATOM 2482 C CG . ASP A 1 324 ? 50.950 -18.370 -25.513 1.00 16.40 ? 324 ASP A CG 1 ATOM 2483 O OD1 . ASP A 1 324 ? 51.874 -19.209 -25.546 1.00 16.54 ? 324 ASP A OD1 1 ATOM 2484 O OD2 . ASP A 1 324 ? 49.806 -18.629 -25.085 1.00 20.36 ? 324 ASP A OD2 1 ATOM 2485 N N . PHE A 1 325 ? 52.749 -13.979 -25.185 1.00 7.73 ? 325 PHE A N 1 ATOM 2486 C CA . PHE A 1 325 ? 52.956 -12.606 -25.634 1.00 6.83 ? 325 PHE A CA 1 ATOM 2487 C C . PHE A 1 325 ? 53.476 -11.741 -24.489 1.00 7.50 ? 325 PHE A C 1 ATOM 2488 O O . PHE A 1 325 ? 53.190 -12.010 -23.323 1.00 7.61 ? 325 PHE A O 1 ATOM 2489 C CB . PHE A 1 325 ? 51.657 -12.031 -26.221 1.00 6.59 ? 325 PHE A CB 1 ATOM 2490 C CG . PHE A 1 325 ? 50.466 -12.139 -25.306 1.00 6.61 ? 325 PHE A CG 1 ATOM 2491 C CD1 . PHE A 1 325 ? 50.247 -11.193 -24.307 1.00 6.08 ? 325 PHE A CD1 1 ATOM 2492 C CD2 . PHE A 1 325 ? 49.562 -13.189 -25.445 1.00 8.01 ? 325 PHE A CD2 1 ATOM 2493 C CE1 . PHE A 1 325 ? 49.141 -11.293 -23.459 1.00 6.83 ? 325 PHE A CE1 1 ATOM 2494 C CE2 . PHE A 1 325 ? 48.455 -13.297 -24.602 1.00 8.37 ? 325 PHE A CE2 1 ATOM 2495 C CZ . PHE A 1 325 ? 48.245 -12.351 -23.610 1.00 7.42 ? 325 PHE A CZ 1 ATOM 2496 N N . TYR A 1 326 ? 54.242 -10.710 -24.834 1.00 6.83 ? 326 TYR A N 1 ATOM 2497 C CA . TYR A 1 326 ? 54.853 -9.817 -23.847 1.00 7.40 ? 326 TYR A CA 1 ATOM 2498 C C . TYR A 1 326 ? 54.396 -8.393 -24.129 1.00 7.05 ? 326 TYR A C 1 ATOM 2499 O O . TYR A 1 326 ? 54.372 -7.968 -25.286 1.00 8.03 ? 326 TYR A O 1 ATOM 2500 C CB . TYR A 1 326 ? 56.371 -9.908 -23.960 1.00 8.84 ? 326 TYR A CB 1 ATOM 2501 C CG . TYR A 1 326 ? 56.878 -11.306 -24.251 1.00 7.24 ? 326 TYR A CG 1 ATOM 2502 C CD1 . TYR A 1 326 ? 57.747 -11.537 -25.315 1.00 9.07 ? 326 TYR A CD1 1 ATOM 2503 C CD2 . TYR A 1 326 ? 56.489 -12.393 -23.470 1.00 10.09 ? 326 TYR A CD2 1 ATOM 2504 C CE1 . TYR A 1 326 ? 58.218 -12.814 -25.597 1.00 10.38 ? 326 TYR A CE1 1 ATOM 2505 C CE2 . TYR A 1 326 ? 56.955 -13.682 -23.745 1.00 10.00 ? 326 TYR A CE2 1 ATOM 2506 C CZ . TYR A 1 326 ? 57.821 -13.879 -24.814 1.00 10.45 ? 326 TYR A CZ 1 ATOM 2507 O OH . TYR A 1 326 ? 58.289 -15.142 -25.110 1.00 13.01 ? 326 TYR A OH 1 ATOM 2508 N N . GLN A 1 327 ? 54.068 -7.641 -23.079 1.00 5.65 ? 327 GLN A N 1 ATOM 2509 C CA . GLN A 1 327 ? 53.545 -6.297 -23.287 1.00 5.62 ? 327 GLN A CA 1 ATOM 2510 C C . GLN A 1 327 ? 54.158 -5.184 -22.444 1.00 7.30 ? 327 GLN A C 1 ATOM 2511 O O . GLN A 1 327 ? 54.780 -5.428 -21.411 1.00 6.34 ? 327 GLN A O 1 ATOM 2512 C CB . GLN A 1 327 ? 52.024 -6.344 -23.084 1.00 6.56 ? 327 GLN A CB 1 ATOM 2513 C CG . GLN A 1 327 ? 51.393 -7.567 -23.757 1.00 9.07 ? 327 GLN A CG 1 ATOM 2514 C CD . GLN A 1 327 ? 49.883 -7.619 -23.651 1.00 7.51 ? 327 GLN A CD 1 ATOM 2515 O OE1 . GLN A 1 327 ? 49.314 -7.506 -22.562 1.00 9.40 ? 327 GLN A OE1 1 ATOM 2516 N NE2 . GLN A 1 327 ? 49.222 -7.808 -24.788 1.00 9.28 ? 327 GLN A NE2 1 ATOM 2517 N N . CYS A 1 328 ? 53.977 -3.951 -22.903 1.00 8.17 ? 328 CYS A N 1 ATOM 2518 C CA . CYS A 1 328 ? 54.497 -2.787 -22.201 1.00 9.99 ? 328 CYS A CA 1 ATOM 2519 C C . CYS A 1 328 ? 53.891 -1.526 -22.802 1.00 10.34 ? 328 CYS A C 1 ATOM 2520 O O . CYS A 1 328 ? 53.136 -1.591 -23.776 1.00 10.11 ? 328 CYS A O 1 ATOM 2521 C CB . CYS A 1 328 ? 56.020 -2.731 -22.316 1.00 10.58 ? 328 CYS A CB 1 ATOM 2522 S SG . CYS A 1 328 ? 56.614 -2.461 -24.002 1.00 17.12 ? 328 CYS A SG 1 ATOM 2523 N N . SER A 1 329 ? 54.219 -0.379 -22.219 1.00 10.35 ? 329 SER A N 1 ATOM 2524 C CA . SER A 1 329 ? 53.699 0.884 -22.715 1.00 10.65 ? 329 SER A CA 1 ATOM 2525 C C . SER A 1 329 ? 54.777 1.951 -22.695 1.00 10.90 ? 329 SER A C 1 ATOM 2526 O O . SER A 1 329 ? 55.572 2.039 -21.758 1.00 13.36 ? 329 SER A O 1 ATOM 2527 C CB . SER A 1 329 ? 52.501 1.337 -21.883 1.00 10.73 ? 329 SER A CB 1 ATOM 2528 O OG . SER A 1 329 ? 51.899 2.477 -22.466 1.00 12.17 ? 329 SER A OG 1 ATOM 2529 N N . PHE A 1 330 ? 54.788 2.755 -23.748 1.00 11.99 ? 330 PHE A N 1 ATOM 2530 C CA . PHE A 1 330 ? 55.755 3.827 -23.926 1.00 13.36 ? 330 PHE A CA 1 ATOM 2531 C C . PHE A 1 330 ? 54.990 5.135 -24.120 1.00 12.34 ? 330 PHE A C 1 ATOM 2532 O O . PHE A 1 330 ? 54.102 5.211 -24.963 1.00 12.70 ? 330 PHE A O 1 ATOM 2533 C CB . PHE A 1 330 ? 56.603 3.506 -25.170 1.00 15.87 ? 330 PHE A CB 1 ATOM 2534 C CG . PHE A 1 330 ? 57.544 4.601 -25.583 1.00 16.59 ? 330 PHE A CG 1 ATOM 2535 C CD1 . PHE A 1 330 ? 58.542 5.047 -24.724 1.00 19.74 ? 330 PHE A CD1 1 ATOM 2536 C CD2 . PHE A 1 330 ? 57.459 5.156 -26.858 1.00 18.55 ? 330 PHE A CD2 1 ATOM 2537 C CE1 . PHE A 1 330 ? 59.446 6.029 -25.130 1.00 19.83 ? 330 PHE A CE1 1 ATOM 2538 C CE2 . PHE A 1 330 ? 58.358 6.138 -27.274 1.00 18.75 ? 330 PHE A CE2 1 ATOM 2539 C CZ . PHE A 1 330 ? 59.352 6.575 -26.409 1.00 20.41 ? 330 PHE A CZ 1 ATOM 2540 N N . SER A 1 331 ? 55.305 6.152 -23.323 1.00 11.41 ? 331 SER A N 1 ATOM 2541 C CA . SER A 1 331 ? 54.644 7.446 -23.476 1.00 11.37 ? 331 SER A CA 1 ATOM 2542 C C . SER A 1 331 ? 55.668 8.389 -24.093 1.00 11.30 ? 331 SER A C 1 ATOM 2543 O O . SER A 1 331 ? 56.847 8.355 -23.736 1.00 10.71 ? 331 SER A O 1 ATOM 2544 C CB . SER A 1 331 ? 54.148 7.983 -22.127 1.00 11.22 ? 331 SER A CB 1 ATOM 2545 O OG . SER A 1 331 ? 55.205 8.152 -21.199 1.00 10.72 ? 331 SER A OG 1 ATOM 2546 N N . SER A 1 332 ? 55.224 9.233 -25.016 1.00 10.53 ? 332 SER A N 1 ATOM 2547 C CA . SER A 1 332 ? 56.153 10.128 -25.687 1.00 12.68 ? 332 SER A CA 1 ATOM 2548 C C . SER A 1 332 ? 55.536 11.448 -26.125 1.00 12.88 ? 332 SER A C 1 ATOM 2549 O O . SER A 1 332 ? 54.323 11.634 -26.062 1.00 12.61 ? 332 SER A O 1 ATOM 2550 C CB . SER A 1 332 ? 56.734 9.408 -26.904 1.00 16.21 ? 332 SER A CB 1 ATOM 2551 O OG . SER A 1 332 ? 57.716 10.196 -27.551 1.00 21.97 ? 332 SER A OG 1 ATOM 2552 N N . LEU A 1 333 ? 56.394 12.357 -26.578 1.00 14.22 ? 333 LEU A N 1 ATOM 2553 C CA . LEU A 1 333 ? 55.975 13.670 -27.054 1.00 14.20 ? 333 LEU A CA 1 ATOM 2554 C C . LEU A 1 333 ? 55.489 13.575 -28.496 1.00 15.46 ? 333 LEU A C 1 ATOM 2555 O O . LEU A 1 333 ? 55.772 12.599 -29.194 1.00 13.92 ? 333 LEU A O 1 ATOM 2556 C CB . LEU A 1 333 ? 57.152 14.645 -26.989 1.00 14.75 ? 333 LEU A CB 1 ATOM 2557 C CG . LEU A 1 333 ? 57.729 14.959 -25.609 1.00 14.67 ? 333 LEU A CG 1 ATOM 2558 C CD1 . LEU A 1 333 ? 58.934 15.875 -25.764 1.00 17.81 ? 333 LEU A CD1 1 ATOM 2559 C CD2 . LEU A 1 333 ? 56.664 15.617 -24.740 1.00 16.53 ? 333 LEU A CD2 1 ATOM 2560 N N . PRO A 1 334 ? 54.746 14.592 -28.962 1.00 15.71 ? 334 PRO A N 1 ATOM 2561 C CA . PRO A 1 334 ? 54.227 14.623 -30.332 1.00 16.81 ? 334 PRO A CA 1 ATOM 2562 C C . PRO A 1 334 ? 55.355 14.952 -31.309 1.00 18.03 ? 334 PRO A C 1 ATOM 2563 O O . PRO A 1 334 ? 56.434 15.372 -30.892 1.00 18.88 ? 334 PRO A O 1 ATOM 2564 C CB . PRO A 1 334 ? 53.173 15.725 -30.269 1.00 17.04 ? 334 PRO A CB 1 ATOM 2565 C CG . PRO A 1 334 ? 53.763 16.678 -29.282 1.00 17.26 ? 334 PRO A CG 1 ATOM 2566 C CD . PRO A 1 334 ? 54.256 15.750 -28.190 1.00 17.17 ? 334 PRO A CD 1 ATOM 2567 N N . PHE A 1 335 ? 55.107 14.770 -32.602 1.00 18.31 ? 335 PHE A N 1 ATOM 2568 C CA . PHE A 1 335 ? 56.126 15.056 -33.612 1.00 18.82 ? 335 PHE A CA 1 ATOM 2569 C C . PHE A 1 335 ? 55.553 15.101 -35.025 1.00 18.61 ? 335 PHE A C 1 ATOM 2570 O O . PHE A 1 335 ? 54.482 14.558 -35.284 1.00 19.57 ? 335 PHE A O 1 ATOM 2571 C CB . PHE A 1 335 ? 57.238 14.003 -33.539 1.00 19.16 ? 335 PHE A CB 1 ATOM 2572 C CG . PHE A 1 335 ? 56.745 12.581 -33.636 1.00 19.52 ? 335 PHE A CG 1 ATOM 2573 C CD1 . PHE A 1 335 ? 56.168 12.103 -34.810 1.00 20.11 ? 335 PHE A CD1 1 ATOM 2574 C CD2 . PHE A 1 335 ? 56.856 11.720 -32.549 1.00 21.01 ? 335 PHE A CD2 1 ATOM 2575 C CE1 . PHE A 1 335 ? 55.710 10.792 -34.900 1.00 21.81 ? 335 PHE A CE1 1 ATOM 2576 C CE2 . PHE A 1 335 ? 56.400 10.404 -32.629 1.00 21.34 ? 335 PHE A CE2 1 ATOM 2577 C CZ . PHE A 1 335 ? 55.826 9.940 -33.806 1.00 19.67 ? 335 PHE A CZ 1 ATOM 2578 N N . THR A 1 336 ? 56.263 15.763 -35.936 1.00 19.65 ? 336 THR A N 1 ATOM 2579 C CA . THR A 1 336 ? 55.821 15.841 -37.326 1.00 19.97 ? 336 THR A CA 1 ATOM 2580 C C . THR A 1 336 ? 56.739 15.009 -38.215 1.00 20.00 ? 336 THR A C 1 ATOM 2581 O O . THR A 1 336 ? 56.411 14.724 -39.367 1.00 20.77 ? 336 THR A O 1 ATOM 2582 C CB . THR A 1 336 ? 55.785 17.296 -37.848 1.00 20.51 ? 336 THR A CB 1 ATOM 2583 O OG1 . THR A 1 336 ? 57.014 17.957 -37.530 1.00 21.60 ? 336 THR A OG1 1 ATOM 2584 C CG2 . THR A 1 336 ? 54.620 18.051 -37.231 1.00 20.59 ? 336 THR A CG2 1 ATOM 2585 N N . THR A 1 337 ? 57.894 14.628 -37.675 1.00 18.71 ? 337 THR A N 1 ATOM 2586 C CA . THR A 1 337 ? 58.843 13.791 -38.403 1.00 16.87 ? 337 THR A CA 1 ATOM 2587 C C . THR A 1 337 ? 58.709 12.402 -37.794 1.00 15.87 ? 337 THR A C 1 ATOM 2588 O O . THR A 1 337 ? 58.973 12.206 -36.609 1.00 14.40 ? 337 THR A O 1 ATOM 2589 C CB . THR A 1 337 ? 60.289 14.281 -38.231 1.00 18.21 ? 337 THR A CB 1 ATOM 2590 O OG1 . THR A 1 337 ? 60.429 15.571 -38.841 1.00 21.37 ? 337 THR A OG1 1 ATOM 2591 C CG2 . THR A 1 337 ? 61.259 13.312 -38.884 1.00 17.53 ? 337 THR A CG2 1 ATOM 2592 N N . PRO A 1 338 ? 58.295 11.416 -38.599 1.00 15.49 ? 338 PRO A N 1 ATOM 2593 C CA . PRO A 1 338 ? 58.128 10.056 -38.090 1.00 16.31 ? 338 PRO A CA 1 ATOM 2594 C C . PRO A 1 338 ? 59.411 9.292 -37.779 1.00 14.29 ? 338 PRO A C 1 ATOM 2595 O O . PRO A 1 338 ? 60.391 9.374 -38.519 1.00 13.62 ? 338 PRO A O 1 ATOM 2596 C CB . PRO A 1 338 ? 57.320 9.384 -39.193 1.00 17.46 ? 338 PRO A CB 1 ATOM 2597 C CG . PRO A 1 338 ? 57.872 10.019 -40.420 1.00 18.66 ? 338 PRO A CG 1 ATOM 2598 C CD . PRO A 1 338 ? 57.949 11.486 -40.031 1.00 16.45 ? 338 PRO A CD 1 ATOM 2599 N N . PRO A 1 339 ? 59.423 8.565 -36.652 1.00 13.85 ? 339 PRO A N 1 ATOM 2600 C CA . PRO A 1 339 ? 60.598 7.777 -36.265 1.00 13.58 ? 339 PRO A CA 1 ATOM 2601 C C . PRO A 1 339 ? 60.490 6.521 -37.127 1.00 12.97 ? 339 PRO A C 1 ATOM 2602 O O . PRO A 1 339 ? 59.567 5.730 -36.949 1.00 11.52 ? 339 PRO A O 1 ATOM 2603 C CB . PRO A 1 339 ? 60.349 7.471 -34.787 1.00 14.12 ? 339 PRO A CB 1 ATOM 2604 C CG . PRO A 1 339 ? 59.374 8.542 -34.352 1.00 17.11 ? 339 PRO A CG 1 ATOM 2605 C CD . PRO A 1 339 ? 58.468 8.659 -35.536 1.00 14.15 ? 339 PRO A CD 1 ATOM 2606 N N . PHE A 1 340 ? 61.411 6.350 -38.069 1.00 11.59 ? 340 PHE A N 1 ATOM 2607 C CA . PHE A 1 340 ? 61.364 5.199 -38.963 1.00 11.04 ? 340 PHE A CA 1 ATOM 2608 C C . PHE A 1 340 ? 61.340 3.877 -38.208 1.00 10.34 ? 340 PHE A C 1 ATOM 2609 O O . PHE A 1 340 ? 62.137 3.659 -37.297 1.00 10.94 ? 340 PHE A O 1 ATOM 2610 C CB . PHE A 1 340 ? 62.558 5.214 -39.917 1.00 10.22 ? 340 PHE A CB 1 ATOM 2611 C CG . PHE A 1 340 ? 62.370 4.347 -41.128 1.00 10.09 ? 340 PHE A CG 1 ATOM 2612 C CD1 . PHE A 1 340 ? 61.657 4.816 -42.226 1.00 10.63 ? 340 PHE A CD1 1 ATOM 2613 C CD2 . PHE A 1 340 ? 62.881 3.052 -41.161 1.00 9.96 ? 340 PHE A CD2 1 ATOM 2614 C CE1 . PHE A 1 340 ? 61.453 4.011 -43.340 1.00 10.91 ? 340 PHE A CE1 1 ATOM 2615 C CE2 . PHE A 1 340 ? 62.681 2.236 -42.275 1.00 9.59 ? 340 PHE A CE2 1 ATOM 2616 C CZ . PHE A 1 340 ? 61.965 2.716 -43.366 1.00 9.78 ? 340 PHE A CZ 1 ATOM 2617 N N . GLY A 1 341 ? 60.421 2.999 -38.598 1.00 9.62 ? 341 GLY A N 1 ATOM 2618 C CA . GLY A 1 341 ? 60.312 1.704 -37.957 1.00 11.03 ? 341 GLY A CA 1 ATOM 2619 C C . GLY A 1 341 ? 59.315 1.653 -36.814 1.00 11.52 ? 341 GLY A C 1 ATOM 2620 O O . GLY A 1 341 ? 58.862 0.570 -36.442 1.00 12.14 ? 341 GLY A O 1 ATOM 2621 N N . PHE A 1 342 ? 58.971 2.809 -36.250 1.00 13.28 ? 342 PHE A N 1 ATOM 2622 C CA . PHE A 1 342 ? 58.018 2.847 -35.142 1.00 13.22 ? 342 PHE A CA 1 ATOM 2623 C C . PHE A 1 342 ? 56.672 2.362 -35.656 1.00 14.12 ? 342 PHE A C 1 ATOM 2624 O O . PHE A 1 342 ? 56.051 1.469 -35.081 1.00 14.36 ? 342 PHE A O 1 ATOM 2625 C CB . PHE A 1 342 ? 57.882 4.263 -34.585 1.00 15.01 ? 342 PHE A CB 1 ATOM 2626 C CG . PHE A 1 342 ? 57.205 4.314 -33.249 1.00 18.29 ? 342 PHE A CG 1 ATOM 2627 C CD1 . PHE A 1 342 ? 57.844 3.817 -32.116 1.00 20.61 ? 342 PHE A CD1 1 ATOM 2628 C CD2 . PHE A 1 342 ? 55.916 4.819 -33.125 1.00 20.28 ? 342 PHE A CD2 1 ATOM 2629 C CE1 . PHE A 1 342 ? 57.206 3.820 -30.877 1.00 22.91 ? 342 PHE A CE1 1 ATOM 2630 C CE2 . PHE A 1 342 ? 55.267 4.828 -31.890 1.00 22.45 ? 342 PHE A CE2 1 ATOM 2631 C CZ . PHE A 1 342 ? 55.915 4.326 -30.765 1.00 22.75 ? 342 PHE A CZ 1 ATOM 2632 N N . PHE A 1 343 ? 56.214 2.979 -36.736 1.00 14.41 ? 343 PHE A N 1 ATOM 2633 C CA . PHE A 1 343 ? 54.977 2.572 -37.373 1.00 14.84 ? 343 PHE A CA 1 ATOM 2634 C C . PHE A 1 343 ? 55.481 1.759 -38.568 1.00 13.78 ? 343 PHE A C 1 ATOM 2635 O O . PHE A 1 343 ? 56.561 2.032 -39.092 1.00 12.53 ? 343 PHE A O 1 ATOM 2636 C CB . PHE A 1 343 ? 54.174 3.814 -37.756 1.00 17.14 ? 343 PHE A CB 1 ATOM 2637 C CG . PHE A 1 343 ? 53.709 4.602 -36.557 1.00 20.81 ? 343 PHE A CG 1 ATOM 2638 C CD1 . PHE A 1 343 ? 53.810 5.988 -36.522 1.00 23.15 ? 343 PHE A CD1 1 ATOM 2639 C CD2 . PHE A 1 343 ? 53.184 3.941 -35.446 1.00 22.01 ? 343 PHE A CD2 1 ATOM 2640 C CE1 . PHE A 1 343 ? 53.397 6.706 -35.394 1.00 25.68 ? 343 PHE A CE1 1 ATOM 2641 C CE2 . PHE A 1 343 ? 52.770 4.646 -34.318 1.00 24.53 ? 343 PHE A CE2 1 ATOM 2642 C CZ . PHE A 1 343 ? 52.876 6.032 -34.292 1.00 24.52 ? 343 PHE A CZ 1 ATOM 2643 N N . PRO A 1 344 ? 54.724 0.739 -38.998 1.00 13.77 ? 344 PRO A N 1 ATOM 2644 C CA . PRO A 1 344 ? 55.134 -0.114 -40.122 1.00 12.53 ? 344 PRO A CA 1 ATOM 2645 C C . PRO A 1 344 ? 55.396 0.514 -41.490 1.00 13.23 ? 344 PRO A C 1 ATOM 2646 O O . PRO A 1 344 ? 56.091 -0.079 -42.308 1.00 11.40 ? 344 PRO A O 1 ATOM 2647 C CB . PRO A 1 344 ? 54.040 -1.178 -40.160 1.00 13.55 ? 344 PRO A CB 1 ATOM 2648 C CG . PRO A 1 344 ? 52.831 -0.423 -39.717 1.00 12.01 ? 344 PRO A CG 1 ATOM 2649 C CD . PRO A 1 344 ? 53.355 0.408 -38.561 1.00 14.22 ? 344 PRO A CD 1 ATOM 2650 N N . SER A 1 345 ? 54.847 1.696 -41.743 1.00 14.73 ? 345 SER A N 1 ATOM 2651 C CA . SER A 1 345 ? 55.067 2.362 -43.023 1.00 18.22 ? 345 SER A CA 1 ATOM 2652 C C . SER A 1 345 ? 55.027 3.875 -42.863 1.00 19.09 ? 345 SER A C 1 ATOM 2653 O O . SER A 1 345 ? 54.637 4.392 -41.820 1.00 17.63 ? 345 SER A O 1 ATOM 2654 C CB . SER A 1 345 ? 54.024 1.913 -44.051 1.00 19.74 ? 345 SER A CB 1 ATOM 2655 O OG . SER A 1 345 ? 52.728 2.348 -43.695 1.00 24.08 ? 345 SER A OG 1 ATOM 2656 N N . SER A 1 346 ? 55.434 4.582 -43.908 1.00 21.48 ? 346 SER A N 1 ATOM 2657 C CA . SER A 1 346 ? 55.472 6.034 -43.888 1.00 24.73 ? 346 SER A CA 1 ATOM 2658 C C . SER A 1 346 ? 54.101 6.707 -43.941 1.00 26.02 ? 346 SER A C 1 ATOM 2659 O O . SER A 1 346 ? 53.950 7.845 -43.507 1.00 28.04 ? 346 SER A O 1 ATOM 2660 C CB . SER A 1 346 ? 56.359 6.537 -45.033 1.00 25.24 ? 346 SER A CB 1 ATOM 2661 O OG . SER A 1 346 ? 56.001 5.941 -46.262 0.50 23.27 ? 346 SER A OG 1 ATOM 2662 N N . SER A 1 347 ? 53.101 6.013 -44.466 1.00 25.99 ? 347 SER A N 1 ATOM 2663 C CA . SER A 1 347 ? 51.769 6.596 -44.541 1.00 27.54 ? 347 SER A CA 1 ATOM 2664 C C . SER A 1 347 ? 51.000 6.265 -43.270 1.00 27.03 ? 347 SER A C 1 ATOM 2665 O O . SER A 1 347 ? 50.109 5.410 -43.266 1.00 28.54 ? 347 SER A O 1 ATOM 2666 C CB . SER A 1 347 ? 51.022 6.076 -45.771 1.00 28.68 ? 347 SER A CB 1 ATOM 2667 O OG . SER A 1 347 ? 50.750 4.697 -45.654 1.00 32.61 ? 347 SER A OG 1 ATOM 2668 N N . TYR A 1 348 ? 51.367 6.947 -42.190 1.00 24.97 ? 348 TYR A N 1 ATOM 2669 C CA . TYR A 1 348 ? 50.742 6.751 -40.888 1.00 22.58 ? 348 TYR A CA 1 ATOM 2670 C C . TYR A 1 348 ? 50.523 8.136 -40.279 1.00 21.29 ? 348 TYR A C 1 ATOM 2671 O O . TYR A 1 348 ? 51.351 9.027 -40.450 1.00 21.94 ? 348 TYR A O 1 ATOM 2672 C CB . TYR A 1 348 ? 51.675 5.941 -39.986 1.00 22.49 ? 348 TYR A CB 1 ATOM 2673 C CG . TYR A 1 348 ? 50.982 5.280 -38.823 1.00 21.51 ? 348 TYR A CG 1 ATOM 2674 C CD1 . TYR A 1 348 ? 50.449 3.997 -38.945 1.00 22.05 ? 348 TYR A CD1 1 ATOM 2675 C CD2 . TYR A 1 348 ? 50.843 5.939 -37.602 1.00 20.01 ? 348 TYR A CD2 1 ATOM 2676 C CE1 . TYR A 1 348 ? 49.794 3.386 -37.876 1.00 20.26 ? 348 TYR A CE1 1 ATOM 2677 C CE2 . TYR A 1 348 ? 50.191 5.337 -36.527 1.00 19.10 ? 348 TYR A CE2 1 ATOM 2678 C CZ . TYR A 1 348 ? 49.668 4.062 -36.673 1.00 20.55 ? 348 TYR A CZ 1 ATOM 2679 O OH . TYR A 1 348 ? 49.001 3.470 -35.626 1.00 18.81 ? 348 TYR A OH 1 ATOM 2680 N N . PRO A 1 349 ? 49.405 8.337 -39.565 1.00 19.98 ? 349 PRO A N 1 ATOM 2681 C CA . PRO A 1 349 ? 49.133 9.644 -38.953 1.00 19.57 ? 349 PRO A CA 1 ATOM 2682 C C . PRO A 1 349 ? 50.130 10.034 -37.859 1.00 19.15 ? 349 PRO A C 1 ATOM 2683 O O . PRO A 1 349 ? 50.614 9.187 -37.111 1.00 18.20 ? 349 PRO A O 1 ATOM 2684 C CB . PRO A 1 349 ? 47.707 9.485 -38.428 1.00 19.38 ? 349 PRO A CB 1 ATOM 2685 C CG . PRO A 1 349 ? 47.632 8.023 -38.107 1.00 18.12 ? 349 PRO A CG 1 ATOM 2686 C CD . PRO A 1 349 ? 48.306 7.393 -39.301 1.00 19.87 ? 349 PRO A CD 1 ATOM 2687 N N . LEU A 1 350 ? 50.425 11.328 -37.776 1.00 19.03 ? 350 LEU A N 1 ATOM 2688 C CA . LEU A 1 350 ? 51.364 11.860 -36.795 1.00 20.54 ? 350 LEU A CA 1 ATOM 2689 C C . LEU A 1 350 ? 50.643 12.396 -35.558 1.00 18.90 ? 350 LEU A C 1 ATOM 2690 O O . LEU A 1 350 ? 49.563 12.976 -35.660 1.00 20.96 ? 350 LEU A O 1 ATOM 2691 C CB . LEU A 1 350 ? 52.178 12.986 -37.432 1.00 22.96 ? 350 LEU A CB 1 ATOM 2692 C CG . LEU A 1 350 ? 53.010 12.590 -38.654 1.00 25.52 ? 350 LEU A CG 1 ATOM 2693 C CD1 . LEU A 1 350 ? 53.028 13.735 -39.652 1.00 27.20 ? 350 LEU A CD1 1 ATOM 2694 C CD2 . LEU A 1 350 ? 54.416 12.213 -38.220 1.00 25.78 ? 350 LEU A CD2 1 ATOM 2695 N N . PRO A 1 351 ? 51.232 12.197 -34.369 1.00 18.35 ? 351 PRO A N 1 ATOM 2696 C CA . PRO A 1 351 ? 50.610 12.683 -33.135 1.00 17.42 ? 351 PRO A CA 1 ATOM 2697 C C . PRO A 1 351 ? 50.949 14.151 -32.889 1.00 17.48 ? 351 PRO A C 1 ATOM 2698 O O . PRO A 1 351 ? 52.124 14.522 -32.886 1.00 16.78 ? 351 PRO A O 1 ATOM 2699 C CB . PRO A 1 351 ? 51.212 11.770 -32.074 1.00 17.05 ? 351 PRO A CB 1 ATOM 2700 C CG . PRO A 1 351 ? 52.606 11.572 -32.582 1.00 17.32 ? 351 PRO A CG 1 ATOM 2701 C CD . PRO A 1 351 ? 52.390 11.335 -34.070 1.00 17.08 ? 351 PRO A CD 1 ATOM 2702 N N . ASN A 1 352 ? 49.927 14.984 -32.700 1.00 18.09 ? 352 ASN A N 1 ATOM 2703 C CA . ASN A 1 352 ? 50.160 16.401 -32.445 1.00 19.23 ? 352 ASN A CA 1 ATOM 2704 C C . ASN A 1 352 ? 50.033 16.734 -30.958 1.00 18.40 ? 352 ASN A C 1 ATOM 2705 O O . ASN A 1 352 ? 50.031 17.902 -30.564 1.00 17.94 ? 352 ASN A O 1 ATOM 2706 C CB . ASN A 1 352 ? 49.227 17.287 -33.302 1.00 22.89 ? 352 ASN A CB 1 ATOM 2707 C CG . ASN A 1 352 ? 47.746 16.960 -33.128 1.00 28.42 ? 352 ASN A CG 1 ATOM 2708 O OD1 . ASN A 1 352 ? 47.193 17.099 -32.036 1.00 29.23 ? 352 ASN A OD1 1 ATOM 2709 N ND2 . ASN A 1 352 ? 47.110 16.541 -34.222 1.00 32.92 ? 352 ASN A ND2 1 ATOM 2710 N N . SER A 1 353 ? 49.945 15.687 -30.140 1.00 15.68 ? 353 SER A N 1 ATOM 2711 C CA . SER A 1 353 ? 49.850 15.815 -28.686 1.00 15.33 ? 353 SER A CA 1 ATOM 2712 C C . SER A 1 353 ? 50.583 14.618 -28.079 1.00 15.22 ? 353 SER A C 1 ATOM 2713 O O . SER A 1 353 ? 50.997 13.718 -28.811 1.00 14.14 ? 353 SER A O 1 ATOM 2714 C CB . SER A 1 353 ? 48.383 15.815 -28.237 1.00 17.38 ? 353 SER A CB 1 ATOM 2715 O OG . SER A 1 353 ? 47.710 14.638 -28.651 1.00 19.17 ? 353 SER A OG 1 ATOM 2716 N N . THR A 1 354 ? 50.755 14.602 -26.758 1.00 13.32 ? 354 THR A N 1 ATOM 2717 C CA . THR A 1 354 ? 51.443 13.477 -26.120 1.00 13.27 ? 354 THR A CA 1 ATOM 2718 C C . THR A 1 354 ? 50.608 12.215 -26.301 1.00 11.47 ? 354 THR A C 1 ATOM 2719 O O . THR A 1 354 ? 49.381 12.279 -26.386 1.00 12.51 ? 354 THR A O 1 ATOM 2720 C CB . THR A 1 354 ? 51.685 13.716 -24.606 1.00 13.53 ? 354 THR A CB 1 ATOM 2721 O OG1 . THR A 1 354 ? 50.438 13.960 -23.945 1.00 13.96 ? 354 THR A OG1 1 ATOM 2722 C CG2 . THR A 1 354 ? 52.612 14.908 -24.394 1.00 14.80 ? 354 THR A CG2 1 ATOM 2723 N N . PHE A 1 355 ? 51.265 11.062 -26.368 1.00 10.75 ? 355 PHE A N 1 ATOM 2724 C CA . PHE A 1 355 ? 50.533 9.818 -26.559 1.00 10.69 ? 355 PHE A CA 1 ATOM 2725 C C . PHE A 1 355 ? 51.174 8.646 -25.836 1.00 8.90 ? 355 PHE A C 1 ATOM 2726 O O . PHE A 1 355 ? 52.309 8.735 -25.369 1.00 8.25 ? 355 PHE A O 1 ATOM 2727 C CB . PHE A 1 355 ? 50.416 9.500 -28.057 1.00 12.95 ? 355 PHE A CB 1 ATOM 2728 C CG . PHE A 1 355 ? 51.707 9.063 -28.697 1.00 13.93 ? 355 PHE A CG 1 ATOM 2729 C CD1 . PHE A 1 355 ? 51.942 7.717 -28.967 1.00 16.24 ? 355 PHE A CD1 1 ATOM 2730 C CD2 . PHE A 1 355 ? 52.685 9.993 -29.034 1.00 14.98 ? 355 PHE A CD2 1 ATOM 2731 C CE1 . PHE A 1 355 ? 53.134 7.304 -29.566 1.00 17.03 ? 355 PHE A CE1 1 ATOM 2732 C CE2 . PHE A 1 355 ? 53.880 9.593 -29.631 1.00 17.47 ? 355 PHE A CE2 1 ATOM 2733 C CZ . PHE A 1 355 ? 54.104 8.245 -29.898 1.00 18.40 ? 355 PHE A CZ 1 ATOM 2734 N N . ALA A 1 356 ? 50.419 7.558 -25.737 1.00 10.19 ? 356 ALA A N 1 ATOM 2735 C CA . ALA A 1 356 ? 50.885 6.336 -25.099 1.00 9.31 ? 356 ALA A CA 1 ATOM 2736 C C . ALA A 1 356 ? 50.780 5.219 -26.125 1.00 8.90 ? 356 ALA A C 1 ATOM 2737 O O . ALA A 1 356 ? 49.759 5.077 -26.804 1.00 8.40 ? 356 ALA A O 1 ATOM 2738 C CB . ALA A 1 356 ? 50.030 6.012 -23.883 1.00 10.62 ? 356 ALA A CB 1 ATOM 2739 N N . HIS A 1 357 ? 51.846 4.436 -26.228 1.00 9.34 ? 357 HIS A N 1 ATOM 2740 C CA . HIS A 1 357 ? 51.932 3.322 -27.164 1.00 8.84 ? 357 HIS A CA 1 ATOM 2741 C C . HIS A 1 357 ? 51.880 2.007 -26.386 1.00 10.02 ? 357 HIS A C 1 ATOM 2742 O O . HIS A 1 357 ? 52.836 1.665 -25.698 1.00 12.29 ? 357 HIS A O 1 ATOM 2743 C CB . HIS A 1 357 ? 53.263 3.431 -27.920 1.00 9.44 ? 357 HIS A CB 1 ATOM 2744 C CG . HIS A 1 357 ? 53.501 2.353 -28.933 1.00 9.43 ? 357 HIS A CG 1 ATOM 2745 N ND1 . HIS A 1 357 ? 52.881 2.335 -30.164 1.00 10.17 ? 357 HIS A ND1 1 ATOM 2746 C CD2 . HIS A 1 357 ? 54.365 1.310 -28.933 1.00 11.31 ? 357 HIS A CD2 1 ATOM 2747 C CE1 . HIS A 1 357 ? 53.360 1.333 -30.882 1.00 12.22 ? 357 HIS A CE1 1 ATOM 2748 N NE2 . HIS A 1 357 ? 54.262 0.696 -30.159 1.00 10.19 ? 357 HIS A NE2 1 ATOM 2749 N N . PHE A 1 358 ? 50.764 1.287 -26.471 1.00 8.87 ? 358 PHE A N 1 ATOM 2750 C CA . PHE A 1 358 ? 50.646 -0.004 -25.794 1.00 8.91 ? 358 PHE A CA 1 ATOM 2751 C C . PHE A 1 358 ? 51.057 -1.056 -26.819 1.00 9.65 ? 358 PHE A C 1 ATOM 2752 O O . PHE A 1 358 ? 50.385 -1.241 -27.835 1.00 9.50 ? 358 PHE A O 1 ATOM 2753 C CB . PHE A 1 358 ? 49.210 -0.256 -25.316 1.00 9.77 ? 358 PHE A CB 1 ATOM 2754 C CG . PHE A 1 358 ? 48.826 0.545 -24.099 1.00 8.59 ? 358 PHE A CG 1 ATOM 2755 C CD1 . PHE A 1 358 ? 48.310 1.830 -24.228 1.00 11.14 ? 358 PHE A CD1 1 ATOM 2756 C CD2 . PHE A 1 358 ? 49.016 0.025 -22.822 1.00 12.12 ? 358 PHE A CD2 1 ATOM 2757 C CE1 . PHE A 1 358 ? 47.989 2.589 -23.098 1.00 11.11 ? 358 PHE A CE1 1 ATOM 2758 C CE2 . PHE A 1 358 ? 48.699 0.774 -21.687 1.00 11.45 ? 358 PHE A CE2 1 ATOM 2759 C CZ . PHE A 1 358 ? 48.184 2.060 -21.828 1.00 11.81 ? 358 PHE A CZ 1 ATOM 2760 N N . ALA A 1 359 ? 52.166 -1.739 -26.548 1.00 8.34 ? 359 ALA A N 1 ATOM 2761 C CA . ALA A 1 359 ? 52.694 -2.731 -27.478 1.00 8.78 ? 359 ALA A CA 1 ATOM 2762 C C . ALA A 1 359 ? 52.595 -4.172 -26.993 1.00 9.28 ? 359 ALA A C 1 ATOM 2763 O O . ALA A 1 359 ? 52.656 -4.450 -25.794 1.00 8.77 ? 359 ALA A O 1 ATOM 2764 C CB . ALA A 1 359 ? 54.145 -2.392 -27.806 1.00 9.09 ? 359 ALA A CB 1 ATOM 2765 N N . SER A 1 360 ? 52.450 -5.086 -27.947 1.00 7.90 ? 360 SER A N 1 ATOM 2766 C CA . SER A 1 360 ? 52.337 -6.509 -27.647 1.00 8.16 ? 360 SER A CA 1 ATOM 2767 C C . SER A 1 360 ? 53.228 -7.314 -28.597 1.00 8.83 ? 360 SER A C 1 ATOM 2768 O O . SER A 1 360 ? 53.084 -7.235 -29.820 1.00 8.96 ? 360 SER A O 1 ATOM 2769 C CB . SER A 1 360 ? 50.876 -6.950 -27.784 1.00 8.98 ? 360 SER A CB 1 ATOM 2770 O OG . SER A 1 360 ? 50.699 -8.292 -27.358 1.00 8.14 ? 360 SER A OG 1 ATOM 2771 N N . LYS A 1 361 ? 54.153 -8.075 -28.019 1.00 7.71 ? 361 LYS A N 1 ATOM 2772 C CA . LYS A 1 361 ? 55.096 -8.894 -28.777 1.00 7.64 ? 361 LYS A CA 1 ATOM 2773 C C . LYS A 1 361 ? 54.732 -10.375 -28.691 1.00 7.17 ? 361 LYS A C 1 ATOM 2774 O O . LYS A 1 361 ? 54.611 -10.923 -27.601 1.00 7.73 ? 361 LYS A O 1 ATOM 2775 C CB . LYS A 1 361 ? 56.516 -8.692 -28.223 1.00 8.29 ? 361 LYS A CB 1 ATOM 2776 C CG . LYS A 1 361 ? 57.604 -9.555 -28.866 1.00 9.56 ? 361 LYS A CG 1 ATOM 2777 C CD . LYS A 1 361 ? 58.943 -9.373 -28.148 1.00 10.26 ? 361 LYS A CD 1 ATOM 2778 C CE . LYS A 1 361 ? 60.028 -10.247 -28.757 1.00 10.35 ? 361 LYS A CE 1 ATOM 2779 N NZ . LYS A 1 361 ? 61.306 -10.209 -27.978 1.00 8.93 ? 361 LYS A NZ 1 ATOM 2780 N N . VAL A 1 362 ? 54.550 -11.020 -29.839 1.00 7.27 ? 362 VAL A N 1 ATOM 2781 C CA . VAL A 1 362 ? 54.232 -12.443 -29.848 1.00 7.67 ? 362 VAL A CA 1 ATOM 2782 C C . VAL A 1 362 ? 55.504 -13.238 -29.554 1.00 8.77 ? 362 VAL A C 1 ATOM 2783 O O . VAL A 1 362 ? 56.575 -12.929 -30.079 1.00 8.20 ? 362 VAL A O 1 ATOM 2784 C CB . VAL A 1 362 ? 53.653 -12.882 -31.217 1.00 8.62 ? 362 VAL A CB 1 ATOM 2785 C CG1 . VAL A 1 362 ? 53.559 -14.400 -31.287 1.00 9.66 ? 362 VAL A CG1 1 ATOM 2786 C CG2 . VAL A 1 362 ? 52.275 -12.266 -31.414 1.00 9.76 ? 362 VAL A CG2 1 ATOM 2787 N N . ALA A 1 363 ? 55.380 -14.248 -28.699 1.00 7.53 ? 363 ALA A N 1 ATOM 2788 C CA . ALA A 1 363 ? 56.508 -15.103 -28.328 1.00 8.24 ? 363 ALA A CA 1 ATOM 2789 C C . ALA A 1 363 ? 57.030 -15.895 -29.530 1.00 9.02 ? 363 ALA A C 1 ATOM 2790 O O . ALA A 1 363 ? 56.295 -16.145 -30.483 1.00 8.53 ? 363 ALA A O 1 ATOM 2791 C CB . ALA A 1 363 ? 56.081 -16.062 -27.222 1.00 8.99 ? 363 ALA A CB 1 ATOM 2792 N N . GLY A 1 364 ? 58.299 -16.293 -29.474 1.00 8.69 ? 364 GLY A N 1 ATOM 2793 C CA . GLY A 1 364 ? 58.887 -17.058 -30.561 1.00 8.36 ? 364 GLY A CA 1 ATOM 2794 C C . GLY A 1 364 ? 59.716 -16.205 -31.501 1.00 7.98 ? 364 GLY A C 1 ATOM 2795 O O . GLY A 1 364 ? 60.814 -15.780 -31.141 1.00 9.04 ? 364 GLY A O 1 ATOM 2796 N N . PRO A 1 365 ? 59.231 -15.946 -32.726 1.00 7.08 ? 365 PRO A N 1 ATOM 2797 C CA . PRO A 1 365 ? 57.955 -16.406 -33.285 1.00 7.21 ? 365 PRO A CA 1 ATOM 2798 C C . PRO A 1 365 ? 58.174 -17.737 -33.993 1.00 7.30 ? 365 PRO A C 1 ATOM 2799 O O . PRO A 1 365 ? 59.314 -18.115 -34.267 1.00 8.74 ? 365 PRO A O 1 ATOM 2800 C CB . PRO A 1 365 ? 57.611 -15.302 -34.267 1.00 7.83 ? 365 PRO A CB 1 ATOM 2801 C CG . PRO A 1 365 ? 58.964 -15.000 -34.858 1.00 7.54 ? 365 PRO A CG 1 ATOM 2802 C CD . PRO A 1 365 ? 59.877 -14.981 -33.636 1.00 7.91 ? 365 PRO A CD 1 ATOM 2803 N N . LEU A 1 366 ? 57.090 -18.441 -34.297 1.00 8.37 ? 366 LEU A N 1 ATOM 2804 C CA . LEU A 1 366 ? 57.209 -19.716 -34.994 1.00 9.21 ? 366 LEU A CA 1 ATOM 2805 C C . LEU A 1 366 ? 57.443 -19.478 -36.485 1.00 8.63 ? 366 LEU A C 1 ATOM 2806 O O . LEU A 1 366 ? 58.101 -20.276 -37.153 1.00 8.70 ? 366 LEU A O 1 ATOM 2807 C CB . LEU A 1 366 ? 55.945 -20.559 -34.776 1.00 10.01 ? 366 LEU A CB 1 ATOM 2808 C CG . LEU A 1 366 ? 55.746 -21.071 -33.345 1.00 11.19 ? 366 LEU A CG 1 ATOM 2809 C CD1 . LEU A 1 366 ? 54.424 -21.804 -33.233 1.00 10.46 ? 366 LEU A CD1 1 ATOM 2810 C CD2 . LEU A 1 366 ? 56.900 -21.994 -32.969 1.00 13.58 ? 366 LEU A CD2 1 ATOM 2811 N N . SER A 1 367 ? 56.905 -18.371 -36.996 1.00 8.02 ? 367 SER A N 1 ATOM 2812 C CA . SER A 1 367 ? 57.043 -18.007 -38.404 1.00 6.30 ? 367 SER A CA 1 ATOM 2813 C C . SER A 1 367 ? 58.463 -17.546 -38.684 1.00 6.93 ? 367 SER A C 1 ATOM 2814 O O . SER A 1 367 ? 59.102 -16.935 -37.828 1.00 6.10 ? 367 SER A O 1 ATOM 2815 C CB . SER A 1 367 ? 56.084 -16.866 -38.757 1.00 7.23 ? 367 SER A CB 1 ATOM 2816 O OG . SER A 1 367 ? 54.740 -17.223 -38.506 1.00 6.91 ? 367 SER A OG 1 ATOM 2817 N N . TYR A 1 368 ? 58.953 -17.830 -39.884 1.00 6.15 ? 368 TYR A N 1 ATOM 2818 C CA . TYR A 1 368 ? 60.295 -17.416 -40.254 1.00 7.83 ? 368 TYR A CA 1 ATOM 2819 C C . TYR A 1 368 ? 60.455 -17.245 -41.757 1.00 7.70 ? 368 TYR A C 1 ATOM 2820 O O . TYR A 1 368 ? 59.627 -17.713 -42.548 1.00 7.26 ? 368 TYR A O 1 ATOM 2821 C CB . TYR A 1 368 ? 61.328 -18.419 -39.728 1.00 7.87 ? 368 TYR A CB 1 ATOM 2822 C CG . TYR A 1 368 ? 61.244 -19.792 -40.355 1.00 9.96 ? 368 TYR A CG 1 ATOM 2823 C CD1 . TYR A 1 368 ? 61.843 -20.059 -41.589 1.00 11.09 ? 368 TYR A CD1 1 ATOM 2824 C CD2 . TYR A 1 368 ? 60.559 -20.823 -39.720 1.00 13.61 ? 368 TYR A CD2 1 ATOM 2825 C CE1 . TYR A 1 368 ? 61.758 -21.329 -42.172 1.00 13.89 ? 368 TYR A CE1 1 ATOM 2826 C CE2 . TYR A 1 368 ? 60.466 -22.090 -40.291 1.00 14.69 ? 368 TYR A CE2 1 ATOM 2827 C CZ . TYR A 1 368 ? 61.065 -22.336 -41.512 1.00 15.24 ? 368 TYR A CZ 1 ATOM 2828 O OH . TYR A 1 368 ? 60.961 -23.590 -42.070 1.00 17.64 ? 368 TYR A OH 1 ATOM 2829 N N . GLY A 1 369 ? 61.527 -16.552 -42.131 1.00 8.28 ? 369 GLY A N 1 ATOM 2830 C CA . GLY A 1 369 ? 61.840 -16.313 -43.528 1.00 7.93 ? 369 GLY A CA 1 ATOM 2831 C C . GLY A 1 369 ? 63.329 -16.494 -43.752 1.00 9.92 ? 369 GLY A C 1 ATOM 2832 O O . GLY A 1 369 ? 63.996 -17.221 -43.008 1.00 11.14 ? 369 GLY A O 1 ATOM 2833 N N . SER A 1 370 ? 63.864 -15.834 -44.773 1.00 8.78 ? 370 SER A N 1 ATOM 2834 C CA . SER A 1 370 ? 65.282 -15.956 -45.069 1.00 9.61 ? 370 SER A CA 1 ATOM 2835 C C . SER A 1 370 ? 65.912 -14.649 -45.512 1.00 9.30 ? 370 SER A C 1 ATOM 2836 O O . SER A 1 370 ? 65.223 -13.664 -45.802 1.00 9.15 ? 370 SER A O 1 ATOM 2837 C CB . SER A 1 370 ? 65.511 -17.012 -46.155 1.00 10.90 ? 370 SER A CB 1 ATOM 2838 O OG . SER A 1 370 ? 64.973 -16.588 -47.394 1.00 13.60 ? 370 SER A OG 1 ATOM 2839 N N . LEU A 1 371 ? 67.238 -14.660 -45.563 1.00 9.20 ? 371 LEU A N 1 ATOM 2840 C CA . LEU A 1 371 ? 68.013 -13.505 -45.978 1.00 9.66 ? 371 LEU A CA 1 ATOM 2841 C C . LEU A 1 371 ? 68.788 -13.861 -47.242 1.00 10.28 ? 371 LEU A C 1 ATOM 2842 O O . LEU A 1 371 ? 69.342 -14.955 -47.349 1.00 11.51 ? 371 LEU A O 1 ATOM 2843 C CB . LEU A 1 371 ? 68.982 -13.097 -44.858 1.00 9.59 ? 371 LEU A CB 1 ATOM 2844 C CG . LEU A 1 371 ? 69.955 -11.936 -45.101 1.00 7.31 ? 371 LEU A CG 1 ATOM 2845 C CD1 . LEU A 1 371 ? 70.368 -11.345 -43.762 1.00 8.52 ? 371 LEU A CD1 1 ATOM 2846 C CD2 . LEU A 1 371 ? 71.177 -12.409 -45.884 1.00 6.50 ? 371 LEU A CD2 1 ATOM 2847 N N . THR A 1 372 ? 68.807 -12.937 -48.196 1.00 10.14 ? 372 THR A N 1 ATOM 2848 C CA . THR A 1 372 ? 69.523 -13.121 -49.455 1.00 11.68 ? 372 THR A CA 1 ATOM 2849 C C . THR A 1 372 ? 70.252 -11.819 -49.766 1.00 10.85 ? 372 THR A C 1 ATOM 2850 O O . THR A 1 372 ? 69.886 -10.759 -49.258 1.00 10.72 ? 372 THR A O 1 ATOM 2851 C CB . THR A 1 372 ? 68.557 -13.445 -50.620 1.00 14.87 ? 372 THR A CB 1 ATOM 2852 O OG1 . THR A 1 372 ? 67.546 -12.431 -50.702 1.00 17.06 ? 372 THR A OG1 1 ATOM 2853 C CG2 . THR A 1 372 ? 67.898 -14.810 -50.412 1.00 17.40 ? 372 THR A CG2 1 ATOM 2854 N N . LEU A 1 373 ? 71.282 -11.892 -50.598 1.00 10.47 ? 373 LEU A N 1 ATOM 2855 C CA . LEU A 1 373 ? 72.040 -10.695 -50.948 1.00 9.98 ? 373 LEU A CA 1 ATOM 2856 C C . LEU A 1 373 ? 71.340 -9.837 -51.995 1.00 10.89 ? 373 LEU A C 1 ATOM 2857 O O . LEU A 1 373 ? 70.668 -10.357 -52.889 1.00 12.21 ? 373 LEU A O 1 ATOM 2858 C CB . LEU A 1 373 ? 73.416 -11.085 -51.490 1.00 9.72 ? 373 LEU A CB 1 ATOM 2859 C CG . LEU A 1 373 ? 74.348 -11.889 -50.585 1.00 9.93 ? 373 LEU A CG 1 ATOM 2860 C CD1 . LEU A 1 373 ? 75.591 -12.298 -51.368 1.00 9.69 ? 373 LEU A CD1 1 ATOM 2861 C CD2 . LEU A 1 373 ? 74.722 -11.054 -49.373 1.00 9.39 ? 373 LEU A CD2 1 ATOM 2862 N N . LYS A 1 374 ? 71.483 -8.519 -51.873 1.00 11.37 ? 374 LYS A N 1 ATOM 2863 C CA . LYS A 1 374 ? 70.920 -7.615 -52.868 1.00 13.24 ? 374 LYS A CA 1 ATOM 2864 C C . LYS A 1 374 ? 72.082 -7.304 -53.807 1.00 14.01 ? 374 LYS A C 1 ATOM 2865 O O . LYS A 1 374 ? 71.893 -7.066 -55.000 1.00 17.25 ? 374 LYS A O 1 ATOM 2866 C CB . LYS A 1 374 ? 70.412 -6.313 -52.255 1.00 15.61 ? 374 LYS A CB 1 ATOM 2867 C CG . LYS A 1 374 ? 69.814 -5.407 -53.324 1.00 19.57 ? 374 LYS A CG 1 ATOM 2868 C CD . LYS A 1 374 ? 70.040 -3.936 -53.044 1.00 24.14 ? 374 LYS A CD 1 ATOM 2869 C CE . LYS A 1 374 ? 69.728 -3.099 -54.277 1.00 25.09 ? 374 LYS A CE 1 ATOM 2870 N NZ . LYS A 1 374 ? 68.339 -3.328 -54.767 1.00 27.43 ? 374 LYS A NZ 1 ATOM 2871 N N . SER A 1 375 ? 73.288 -7.300 -53.247 1.00 11.77 ? 375 SER A N 1 ATOM 2872 C CA . SER A 1 375 ? 74.505 -7.072 -54.020 1.00 11.07 ? 375 SER A CA 1 ATOM 2873 C C . SER A 1 375 ? 75.409 -8.275 -53.797 1.00 11.10 ? 375 SER A C 1 ATOM 2874 O O . SER A 1 375 ? 75.619 -8.696 -52.663 1.00 11.08 ? 375 SER A O 1 ATOM 2875 C CB . SER A 1 375 ? 75.234 -5.812 -53.558 1.00 10.57 ? 375 SER A CB 1 ATOM 2876 O OG . SER A 1 375 ? 76.469 -5.684 -54.246 1.00 11.89 ? 375 SER A OG 1 ATOM 2877 N N . SER A 1 376 ? 75.949 -8.826 -54.876 1.00 12.85 ? 376 SER A N 1 ATOM 2878 C CA . SER A 1 376 ? 76.816 -9.991 -54.759 1.00 13.48 ? 376 SER A CA 1 ATOM 2879 C C . SER A 1 376 ? 78.248 -9.610 -54.406 1.00 12.75 ? 376 SER A C 1 ATOM 2880 O O . SER A 1 376 ? 79.093 -10.485 -54.213 1.00 12.84 ? 376 SER A O 1 ATOM 2881 C CB . SER A 1 376 ? 76.815 -10.778 -56.074 1.00 14.48 ? 376 SER A CB 1 ATOM 2882 O OG . SER A 1 376 ? 77.398 -10.014 -57.121 1.00 16.20 ? 376 SER A OG 1 ATOM 2883 N N . SER A 1 377 ? 78.520 -8.311 -54.295 1.00 13.41 ? 377 SER A N 1 ATOM 2884 C CA . SER A 1 377 ? 79.880 -7.863 -54.010 1.00 13.72 ? 377 SER A CA 1 ATOM 2885 C C . SER A 1 377 ? 80.055 -6.731 -53.005 1.00 14.20 ? 377 SER A C 1 ATOM 2886 O O . SER A 1 377 ? 81.138 -6.571 -52.446 1.00 16.33 ? 377 SER A O 1 ATOM 2887 C CB . SER A 1 377 ? 80.550 -7.435 -55.316 1.00 14.48 ? 377 SER A CB 1 ATOM 2888 O OG . SER A 1 377 ? 79.900 -6.293 -55.856 1.00 15.40 ? 377 SER A OG 1 ATOM 2889 N N . ASN A 1 378 ? 79.009 -5.943 -52.780 1.00 12.48 ? 378 ASN A N 1 ATOM 2890 C CA . ASN A 1 378 ? 79.107 -4.802 -51.871 1.00 11.72 ? 378 ASN A CA 1 ATOM 2891 C C . ASN A 1 378 ? 78.430 -5.046 -50.528 1.00 11.13 ? 378 ASN A C 1 ATOM 2892 O O . ASN A 1 378 ? 77.204 -5.101 -50.447 1.00 10.39 ? 378 ASN A O 1 ATOM 2893 C CB . ASN A 1 378 ? 78.483 -3.575 -52.534 1.00 12.49 ? 378 ASN A CB 1 ATOM 2894 C CG . ASN A 1 378 ? 78.869 -2.280 -51.850 1.00 14.77 ? 378 ASN A CG 1 ATOM 2895 O OD1 . ASN A 1 378 ? 79.214 -2.263 -50.669 1.00 14.24 ? 378 ASN A OD1 1 ATOM 2896 N ND2 . ASN A 1 378 ? 78.800 -1.180 -52.592 1.00 15.76 ? 378 ASN A ND2 1 ATOM 2897 N N . VAL A 1 379 ? 79.235 -5.166 -49.475 1.00 9.79 ? 379 VAL A N 1 ATOM 2898 C CA . VAL A 1 379 ? 78.717 -5.411 -48.133 1.00 8.27 ? 379 VAL A CA 1 ATOM 2899 C C . VAL A 1 379 ? 77.968 -4.203 -47.558 1.00 9.20 ? 379 VAL A C 1 ATOM 2900 O O . VAL A 1 379 ? 77.254 -4.329 -46.561 1.00 8.11 ? 379 VAL A O 1 ATOM 2901 C CB . VAL A 1 379 ? 79.865 -5.817 -47.162 1.00 8.50 ? 379 VAL A CB 1 ATOM 2902 C CG1 . VAL A 1 379 ? 80.725 -4.605 -46.820 1.00 8.35 ? 379 VAL A CG1 1 ATOM 2903 C CG2 . VAL A 1 379 ? 79.288 -6.457 -45.907 1.00 7.67 ? 379 VAL A CG2 1 ATOM 2904 N N . ARG A 1 380 ? 78.125 -3.036 -48.182 1.00 10.69 ? 380 ARG A N 1 ATOM 2905 C CA . ARG A 1 380 ? 77.438 -1.838 -47.705 1.00 11.96 ? 380 ARG A CA 1 ATOM 2906 C C . ARG A 1 380 ? 76.004 -1.762 -48.231 1.00 10.94 ? 380 ARG A C 1 ATOM 2907 O O . ARG A 1 380 ? 75.245 -0.857 -47.869 1.00 11.05 ? 380 ARG A O 1 ATOM 2908 C CB . ARG A 1 380 ? 78.197 -0.575 -48.115 1.00 14.68 ? 380 ARG A CB 1 ATOM 2909 C CG . ARG A 1 380 ? 79.578 -0.428 -47.499 1.00 20.05 ? 380 ARG A CG 1 ATOM 2910 C CD . ARG A 1 380 ? 80.245 0.829 -48.040 1.00 25.12 ? 380 ARG A CD 1 ATOM 2911 N NE . ARG A 1 380 ? 81.664 0.910 -47.706 1.00 29.29 ? 380 ARG A NE 1 ATOM 2912 C CZ . ARG A 1 380 ? 82.144 1.381 -46.559 1.00 31.74 ? 380 ARG A CZ 1 ATOM 2913 N NH1 . ARG A 1 380 ? 81.318 1.825 -45.618 1.00 32.31 ? 380 ARG A NH1 1 ATOM 2914 N NH2 . ARG A 1 380 ? 83.454 1.407 -46.357 1.00 32.39 ? 380 ARG A NH2 1 ATOM 2915 N N . VAL A 1 381 ? 75.637 -2.704 -49.095 1.00 10.37 ? 381 VAL A N 1 ATOM 2916 C CA . VAL A 1 381 ? 74.285 -2.743 -49.638 1.00 10.86 ? 381 VAL A CA 1 ATOM 2917 C C . VAL A 1 381 ? 73.462 -3.697 -48.774 1.00 11.14 ? 381 VAL A C 1 ATOM 2918 O O . VAL A 1 381 ? 73.766 -4.883 -48.685 1.00 12.01 ? 381 VAL A O 1 ATOM 2919 C CB . VAL A 1 381 ? 74.275 -3.239 -51.097 1.00 10.08 ? 381 VAL A CB 1 ATOM 2920 C CG1 . VAL A 1 381 ? 72.846 -3.423 -51.570 1.00 11.96 ? 381 VAL A CG1 1 ATOM 2921 C CG2 . VAL A 1 381 ? 74.987 -2.240 -51.994 1.00 12.31 ? 381 VAL A CG2 1 ATOM 2922 N N . SER A 1 382 ? 72.421 -3.171 -48.139 1.00 11.29 ? 382 SER A N 1 ATOM 2923 C CA . SER A 1 382 ? 71.576 -3.974 -47.261 1.00 11.86 ? 382 SER A CA 1 ATOM 2924 C C . SER A 1 382 ? 71.030 -5.231 -47.928 1.00 11.17 ? 382 SER A C 1 ATOM 2925 O O . SER A 1 382 ? 70.591 -5.200 -49.079 1.00 11.16 ? 382 SER A O 1 ATOM 2926 C CB . SER A 1 382 ? 70.407 -3.133 -46.744 1.00 14.58 ? 382 SER A CB 1 ATOM 2927 O OG A SER A 1 382 ? 70.871 -1.986 -46.058 0.50 16.50 ? 382 SER A OG 1 ATOM 2928 O OG B SER A 1 382 ? 69.596 -3.860 -45.835 0.50 16.59 ? 382 SER A OG 1 ATOM 2929 N N . PRO A 1 383 ? 71.067 -6.363 -47.209 1.00 11.23 ? 383 PRO A N 1 ATOM 2930 C CA . PRO A 1 383 ? 70.565 -7.636 -47.733 1.00 11.01 ? 383 PRO A CA 1 ATOM 2931 C C . PRO A 1 383 ? 69.041 -7.618 -47.787 1.00 11.58 ? 383 PRO A C 1 ATOM 2932 O O . PRO A 1 383 ? 68.398 -6.790 -47.136 1.00 12.10 ? 383 PRO A O 1 ATOM 2933 C CB . PRO A 1 383 ? 71.054 -8.656 -46.705 1.00 11.66 ? 383 PRO A CB 1 ATOM 2934 C CG . PRO A 1 383 ? 72.257 -8.010 -46.099 1.00 14.26 ? 383 PRO A CG 1 ATOM 2935 C CD . PRO A 1 383 ? 71.820 -6.575 -45.960 1.00 11.73 ? 383 PRO A CD 1 ATOM 2936 N N . ASN A 1 384 ? 68.470 -8.532 -48.564 1.00 10.12 ? 384 ASN A N 1 ATOM 2937 C CA . ASN A 1 384 ? 67.024 -8.650 -48.651 1.00 12.14 ? 384 ASN A CA 1 ATOM 2938 C C . ASN A 1 384 ? 66.621 -9.591 -47.521 1.00 10.88 ? 384 ASN A C 1 ATOM 2939 O O . ASN A 1 384 ? 67.286 -10.601 -47.284 1.00 11.87 ? 384 ASN A O 1 ATOM 2940 C CB . ASN A 1 384 ? 66.617 -9.268 -49.989 1.00 13.54 ? 384 ASN A CB 1 ATOM 2941 C CG . ASN A 1 384 ? 65.113 -9.415 -50.131 0.50 14.42 ? 384 ASN A CG 1 ATOM 2942 O OD1 . ASN A 1 384 ? 64.393 -8.432 -50.306 0.50 15.89 ? 384 ASN A OD1 1 ATOM 2943 N ND2 . ASN A 1 384 ? 64.630 -10.650 -50.047 0.50 15.41 ? 384 ASN A ND2 1 ATOM 2944 N N . VAL A 1 385 ? 65.551 -9.263 -46.809 1.00 9.17 ? 385 VAL A N 1 ATOM 2945 C CA . VAL A 1 385 ? 65.091 -10.129 -45.732 1.00 7.98 ? 385 VAL A CA 1 ATOM 2946 C C . VAL A 1 385 ? 63.575 -10.214 -45.711 1.00 7.93 ? 385 VAL A C 1 ATOM 2947 O O . VAL A 1 385 ? 62.890 -9.215 -45.919 1.00 9.09 ? 385 VAL A O 1 ATOM 2948 C CB . VAL A 1 385 ? 65.573 -9.638 -44.336 1.00 8.78 ? 385 VAL A CB 1 ATOM 2949 C CG1 A VAL A 1 385 ? 67.084 -9.718 -44.248 0.50 5.77 ? 385 VAL A CG1 1 ATOM 2950 C CG1 B VAL A 1 385 ? 65.018 -8.309 -43.992 0.50 5.95 ? 385 VAL A CG1 1 ATOM 2951 C CG2 A VAL A 1 385 ? 65.103 -8.214 -44.083 0.50 4.80 ? 385 VAL A CG2 1 ATOM 2952 C CG2 B VAL A 1 385 ? 65.355 -10.690 -43.291 0.50 4.78 ? 385 VAL A CG2 1 ATOM 2953 N N . LYS A 1 386 ? 63.059 -11.418 -45.485 1.00 7.42 ? 386 LYS A N 1 ATOM 2954 C CA . LYS A 1 386 ? 61.617 -11.624 -45.393 1.00 9.18 ? 386 LYS A CA 1 ATOM 2955 C C . LYS A 1 386 ? 61.353 -12.409 -44.116 1.00 9.83 ? 386 LYS A C 1 ATOM 2956 O O . LYS A 1 386 ? 62.066 -13.364 -43.817 1.00 9.81 ? 386 LYS A O 1 ATOM 2957 C CB . LYS A 1 386 ? 61.081 -12.389 -46.606 1.00 10.09 ? 386 LYS A CB 1 ATOM 2958 C CG . LYS A 1 386 ? 59.560 -12.462 -46.608 1.00 11.46 ? 386 LYS A CG 1 ATOM 2959 C CD . LYS A 1 386 ? 58.989 -12.853 -47.958 1.00 13.05 ? 386 LYS A CD 1 ATOM 2960 C CE . LYS A 1 386 ? 57.475 -12.697 -47.958 1.00 13.21 ? 386 LYS A CE 1 ATOM 2961 N NZ . LYS A 1 386 ? 56.868 -13.062 -49.271 1.00 14.95 ? 386 LYS A NZ 1 ATOM 2962 N N . PHE A 1 387 ? 60.335 -12.007 -43.360 1.00 7.84 ? 387 PHE A N 1 ATOM 2963 C CA . PHE A 1 387 ? 60.030 -12.676 -42.102 1.00 7.90 ? 387 PHE A CA 1 ATOM 2964 C C . PHE A 1 387 ? 58.767 -13.534 -42.097 1.00 7.70 ? 387 PHE A C 1 ATOM 2965 O O . PHE A 1 387 ? 58.578 -14.355 -41.200 1.00 8.82 ? 387 PHE A O 1 ATOM 2966 C CB . PHE A 1 387 ? 59.962 -11.634 -40.982 1.00 7.24 ? 387 PHE A CB 1 ATOM 2967 C CG . PHE A 1 387 ? 61.259 -10.906 -40.758 1.00 7.94 ? 387 PHE A CG 1 ATOM 2968 C CD1 . PHE A 1 387 ? 61.343 -9.529 -40.937 1.00 7.07 ? 387 PHE A CD1 1 ATOM 2969 C CD2 . PHE A 1 387 ? 62.395 -11.598 -40.345 1.00 6.73 ? 387 PHE A CD2 1 ATOM 2970 C CE1 . PHE A 1 387 ? 62.543 -8.849 -40.702 1.00 6.59 ? 387 PHE A CE1 1 ATOM 2971 C CE2 . PHE A 1 387 ? 63.594 -10.933 -40.109 1.00 6.98 ? 387 PHE A CE2 1 ATOM 2972 C CZ . PHE A 1 387 ? 63.671 -9.555 -40.285 1.00 7.49 ? 387 PHE A CZ 1 ATOM 2973 N N . ASN A 1 388 ? 57.911 -13.341 -43.097 1.00 7.07 ? 388 ASN A N 1 ATOM 2974 C CA . ASN A 1 388 ? 56.665 -14.095 -43.229 1.00 6.18 ? 388 ASN A CA 1 ATOM 2975 C C . ASN A 1 388 ? 55.784 -14.042 -41.989 1.00 5.67 ? 388 ASN A C 1 ATOM 2976 O O . ASN A 1 388 ? 55.350 -15.071 -41.471 1.00 7.57 ? 388 ASN A O 1 ATOM 2977 C CB . ASN A 1 388 ? 56.972 -15.550 -43.599 1.00 6.27 ? 388 ASN A CB 1 ATOM 2978 C CG . ASN A 1 388 ? 57.643 -15.668 -44.954 1.00 8.73 ? 388 ASN A CG 1 ATOM 2979 O OD1 . ASN A 1 388 ? 57.151 -15.133 -45.945 1.00 10.38 ? 388 ASN A OD1 1 ATOM 2980 N ND2 . ASN A 1 388 ? 58.772 -16.364 -45.003 1.00 9.99 ? 388 ASN A ND2 1 ATOM 2981 N N . TYR A 1 389 ? 55.515 -12.827 -41.526 1.00 6.54 ? 389 TYR A N 1 ATOM 2982 C CA . TYR A 1 389 ? 54.689 -12.629 -40.348 1.00 6.42 ? 389 TYR A CA 1 ATOM 2983 C C . TYR A 1 389 ? 53.388 -13.407 -40.457 1.00 7.47 ? 389 TYR A C 1 ATOM 2984 O O . TYR A 1 389 ? 52.735 -13.411 -41.507 1.00 8.07 ? 389 TYR A O 1 ATOM 2985 C CB . TYR A 1 389 ? 54.359 -11.144 -40.154 1.00 6.54 ? 389 TYR A CB 1 ATOM 2986 C CG . TYR A 1 389 ? 55.561 -10.241 -40.003 1.00 6.47 ? 389 TYR A CG 1 ATOM 2987 C CD1 . TYR A 1 389 ? 56.076 -9.544 -41.094 1.00 7.53 ? 389 TYR A CD1 1 ATOM 2988 C CD2 . TYR A 1 389 ? 56.187 -10.085 -38.765 1.00 5.53 ? 389 TYR A CD2 1 ATOM 2989 C CE1 . TYR A 1 389 ? 57.187 -8.709 -40.962 1.00 6.55 ? 389 TYR A CE1 1 ATOM 2990 C CE2 . TYR A 1 389 ? 57.301 -9.253 -38.618 1.00 8.22 ? 389 TYR A CE2 1 ATOM 2991 C CZ . TYR A 1 389 ? 57.793 -8.568 -39.724 1.00 6.81 ? 389 TYR A CZ 1 ATOM 2992 O OH . TYR A 1 389 ? 58.884 -7.735 -39.592 1.00 6.86 ? 389 TYR A OH 1 ATOM 2993 N N . TYR A 1 390 ? 53.033 -14.073 -39.364 1.00 7.40 ? 390 TYR A N 1 ATOM 2994 C CA . TYR A 1 390 ? 51.802 -14.840 -39.267 1.00 7.20 ? 390 TYR A CA 1 ATOM 2995 C C . TYR A 1 390 ? 51.613 -15.978 -40.271 1.00 9.66 ? 390 TYR A C 1 ATOM 2996 O O . TYR A 1 390 ? 50.492 -16.448 -40.477 1.00 10.86 ? 390 TYR A O 1 ATOM 2997 C CB . TYR A 1 390 ? 50.611 -13.867 -39.293 1.00 8.35 ? 390 TYR A CB 1 ATOM 2998 C CG . TYR A 1 390 ? 50.642 -12.920 -38.107 1.00 8.30 ? 390 TYR A CG 1 ATOM 2999 C CD1 . TYR A 1 390 ? 50.488 -11.538 -38.269 1.00 11.13 ? 390 TYR A CD1 1 ATOM 3000 C CD2 . TYR A 1 390 ? 50.886 -13.406 -36.825 1.00 9.55 ? 390 TYR A CD2 1 ATOM 3001 C CE1 . TYR A 1 390 ? 50.588 -10.668 -37.170 1.00 11.86 ? 390 TYR A CE1 1 ATOM 3002 C CE2 . TYR A 1 390 ? 50.986 -12.553 -35.732 1.00 10.85 ? 390 TYR A CE2 1 ATOM 3003 C CZ . TYR A 1 390 ? 50.841 -11.193 -35.905 1.00 12.58 ? 390 TYR A CZ 1 ATOM 3004 O OH . TYR A 1 390 ? 50.980 -10.375 -34.800 1.00 12.51 ? 390 TYR A OH 1 ATOM 3005 N N . SER A 1 391 ? 52.702 -16.435 -40.885 1.00 9.23 ? 391 SER A N 1 ATOM 3006 C CA . SER A 1 391 ? 52.603 -17.552 -41.824 1.00 10.39 ? 391 SER A CA 1 ATOM 3007 C C . SER A 1 391 ? 52.257 -18.797 -41.002 1.00 11.87 ? 391 SER A C 1 ATOM 3008 O O . SER A 1 391 ? 51.613 -19.729 -41.493 1.00 12.62 ? 391 SER A O 1 ATOM 3009 C CB . SER A 1 391 ? 53.920 -17.744 -42.589 1.00 11.89 ? 391 SER A CB 1 ATOM 3010 O OG . SER A 1 391 ? 55.021 -17.915 -41.715 1.00 12.49 ? 391 SER A OG 1 ATOM 3011 N N . ASN A 1 392 ? 52.695 -18.805 -39.746 1.00 9.89 ? 392 ASN A N 1 ATOM 3012 C CA . ASN A 1 392 ? 52.379 -19.897 -38.834 1.00 10.96 ? 392 ASN A CA 1 ATOM 3013 C C . ASN A 1 392 ? 51.178 -19.392 -38.039 1.00 11.64 ? 392 ASN A C 1 ATOM 3014 O O . ASN A 1 392 ? 51.278 -18.411 -37.302 1.00 10.73 ? 392 ASN A O 1 ATOM 3015 C CB . ASN A 1 392 ? 53.546 -20.187 -37.893 1.00 11.98 ? 392 ASN A CB 1 ATOM 3016 C CG . ASN A 1 392 ? 53.327 -21.447 -37.076 1.00 14.45 ? 392 ASN A CG 1 ATOM 3017 O OD1 . ASN A 1 392 ? 52.437 -21.497 -36.228 1.00 11.76 ? 392 ASN A OD1 1 ATOM 3018 N ND2 . ASN A 1 392 ? 54.136 -22.469 -37.346 1.00 17.52 ? 392 ASN A ND2 1 ATOM 3019 N N . LEU A 1 393 ? 50.041 -20.059 -38.194 1.00 10.32 ? 393 LEU A N 1 ATOM 3020 C CA . LEU A 1 393 ? 48.817 -19.631 -37.527 1.00 9.96 ? 393 LEU A CA 1 ATOM 3021 C C . LEU A 1 393 ? 48.857 -19.585 -36.005 1.00 9.33 ? 393 LEU A C 1 ATOM 3022 O O . LEU A 1 393 ? 48.042 -18.896 -35.389 1.00 10.35 ? 393 LEU A O 1 ATOM 3023 C CB . LEU A 1 393 ? 47.644 -20.495 -37.996 1.00 11.02 ? 393 LEU A CB 1 ATOM 3024 C CG . LEU A 1 393 ? 47.347 -20.372 -39.494 1.00 13.38 ? 393 LEU A CG 1 ATOM 3025 C CD1 . LEU A 1 393 ? 46.217 -21.317 -39.869 1.00 14.65 ? 393 LEU A CD1 1 ATOM 3026 C CD2 . LEU A 1 393 ? 46.981 -18.934 -39.834 1.00 13.88 ? 393 LEU A CD2 1 ATOM 3027 N N . THR A 1 394 ? 49.782 -20.312 -35.387 1.00 8.80 ? 394 THR A N 1 ATOM 3028 C CA . THR A 1 394 ? 49.869 -20.279 -33.934 1.00 9.56 ? 394 THR A CA 1 ATOM 3029 C C . THR A 1 394 ? 50.315 -18.878 -33.506 1.00 9.10 ? 394 THR A C 1 ATOM 3030 O O . THR A 1 394 ? 49.885 -18.377 -32.465 1.00 8.63 ? 394 THR A O 1 ATOM 3031 C CB . THR A 1 394 ? 50.845 -21.345 -33.398 1.00 11.64 ? 394 THR A CB 1 ATOM 3032 O OG1 . THR A 1 394 ? 50.352 -22.650 -33.731 1.00 14.18 ? 394 THR A OG1 1 ATOM 3033 C CG2 . THR A 1 394 ? 50.961 -21.245 -31.885 1.00 13.33 ? 394 THR A CG2 1 ATOM 3034 N N . ASP A 1 395 ? 51.161 -18.239 -34.314 1.00 8.41 ? 395 ASP A N 1 ATOM 3035 C CA . ASP A 1 395 ? 51.608 -16.881 -34.000 1.00 8.21 ? 395 ASP A CA 1 ATOM 3036 C C . ASP A 1 395 ? 50.391 -15.959 -34.018 1.00 7.18 ? 395 ASP A C 1 ATOM 3037 O O . ASP A 1 395 ? 50.253 -15.071 -33.177 1.00 9.01 ? 395 ASP A O 1 ATOM 3038 C CB . ASP A 1 395 ? 52.608 -16.348 -35.036 1.00 8.23 ? 395 ASP A CB 1 ATOM 3039 C CG . ASP A 1 395 ? 54.001 -16.945 -34.899 1.00 6.20 ? 395 ASP A CG 1 ATOM 3040 O OD1 . ASP A 1 395 ? 54.328 -17.523 -33.837 1.00 8.16 ? 395 ASP A OD1 1 ATOM 3041 O OD2 . ASP A 1 395 ? 54.782 -16.809 -35.867 1.00 7.46 ? 395 ASP A OD2 1 ATOM 3042 N N . LEU A 1 396 ? 49.518 -16.165 -34.999 1.00 7.13 ? 396 LEU A N 1 ATOM 3043 C CA . LEU A 1 396 ? 48.323 -15.343 -35.136 1.00 7.20 ? 396 LEU A CA 1 ATOM 3044 C C . LEU A 1 396 ? 47.389 -15.520 -33.943 1.00 8.86 ? 396 LEU A C 1 ATOM 3045 O O . LEU A 1 396 ? 46.821 -14.550 -33.449 1.00 8.12 ? 396 LEU A O 1 ATOM 3046 C CB . LEU A 1 396 ? 47.592 -15.694 -36.437 1.00 6.82 ? 396 LEU A CB 1 ATOM 3047 C CG . LEU A 1 396 ? 46.373 -14.838 -36.792 1.00 9.34 ? 396 LEU A CG 1 ATOM 3048 C CD1 . LEU A 1 396 ? 46.773 -13.371 -36.892 1.00 10.29 ? 396 LEU A CD1 1 ATOM 3049 C CD2 . LEU A 1 396 ? 45.786 -15.320 -38.111 1.00 10.87 ? 396 LEU A CD2 1 ATOM 3050 N N . SER A 1 397 ? 47.233 -16.758 -33.480 1.00 8.03 ? 397 SER A N 1 ATOM 3051 C CA . SER A 1 397 ? 46.367 -17.021 -32.337 1.00 9.10 ? 397 SER A CA 1 ATOM 3052 C C . SER A 1 397 ? 46.917 -16.283 -31.120 1.00 8.34 ? 397 SER A C 1 ATOM 3053 O O . SER A 1 397 ? 46.161 -15.749 -30.309 1.00 8.39 ? 397 SER A O 1 ATOM 3054 C CB . SER A 1 397 ? 46.293 -18.526 -32.051 1.00 11.31 ? 397 SER A CB 1 ATOM 3055 O OG . SER A 1 397 ? 47.554 -19.038 -31.656 0.50 13.21 ? 397 SER A OG 1 ATOM 3056 N N . HIS A 1 398 ? 48.239 -16.247 -31.003 1.00 8.47 ? 398 HIS A N 1 ATOM 3057 C CA . HIS A 1 398 ? 48.873 -15.558 -29.886 1.00 8.26 ? 398 HIS A CA 1 ATOM 3058 C C . HIS A 1 398 ? 48.698 -14.045 -30.005 1.00 9.34 ? 398 HIS A C 1 ATOM 3059 O O . HIS A 1 398 ? 48.552 -13.360 -28.991 1.00 10.10 ? 398 HIS A O 1 ATOM 3060 C CB . HIS A 1 398 ? 50.352 -15.950 -29.799 1.00 7.70 ? 398 HIS A CB 1 ATOM 3061 C CG . HIS A 1 398 ? 50.560 -17.384 -29.419 1.00 8.51 ? 398 HIS A CG 1 ATOM 3062 N ND1 . HIS A 1 398 ? 51.766 -18.037 -29.580 1.00 10.56 ? 398 HIS A ND1 1 ATOM 3063 C CD2 . HIS A 1 398 ? 49.714 -18.295 -28.881 1.00 10.89 ? 398 HIS A CD2 1 ATOM 3064 C CE1 . HIS A 1 398 ? 51.650 -19.283 -29.161 1.00 9.87 ? 398 HIS A CE1 1 ATOM 3065 N NE2 . HIS A 1 398 ? 50.413 -19.467 -28.731 1.00 10.87 ? 398 HIS A NE2 1 ATOM 3066 N N . CYS A 1 399 ? 48.693 -13.522 -31.231 1.00 8.96 ? 399 CYS A N 1 ATOM 3067 C CA . CYS A 1 399 ? 48.490 -12.082 -31.423 1.00 7.93 ? 399 CYS A CA 1 ATOM 3068 C C . CYS A 1 399 ? 47.087 -11.727 -30.964 1.00 7.69 ? 399 CYS A C 1 ATOM 3069 O O . CYS A 1 399 ? 46.873 -10.730 -30.273 1.00 7.28 ? 399 CYS A O 1 ATOM 3070 C CB . CYS A 1 399 ? 48.621 -11.671 -32.897 1.00 9.26 ? 399 CYS A CB 1 ATOM 3071 S SG . CYS A 1 399 ? 48.222 -9.902 -33.146 1.00 14.08 ? 399 CYS A SG 1 ATOM 3072 N N . VAL A 1 400 ? 46.121 -12.547 -31.362 1.00 7.90 ? 400 VAL A N 1 ATOM 3073 C CA . VAL A 1 400 ? 44.741 -12.306 -30.985 1.00 7.04 ? 400 VAL A CA 1 ATOM 3074 C C . VAL A 1 400 ? 44.604 -12.256 -29.468 1.00 7.87 ? 400 VAL A C 1 ATOM 3075 O O . VAL A 1 400 ? 44.020 -11.318 -28.928 1.00 7.22 ? 400 VAL A O 1 ATOM 3076 C CB . VAL A 1 400 ? 43.809 -13.390 -31.565 1.00 6.79 ? 400 VAL A CB 1 ATOM 3077 C CG1 . VAL A 1 400 ? 42.402 -13.222 -31.009 1.00 6.94 ? 400 VAL A CG1 1 ATOM 3078 C CG2 . VAL A 1 400 ? 43.784 -13.278 -33.089 1.00 7.17 ? 400 VAL A CG2 1 ATOM 3079 N N . SER A 1 401 ? 45.157 -13.252 -28.779 1.00 7.25 ? 401 SER A N 1 ATOM 3080 C CA . SER A 1 401 ? 45.092 -13.286 -27.321 1.00 6.73 ? 401 SER A CA 1 ATOM 3081 C C . SER A 1 401 ? 45.767 -12.046 -26.745 1.00 6.97 ? 401 SER A C 1 ATOM 3082 O O . SER A 1 401 ? 45.261 -11.424 -25.806 1.00 7.35 ? 401 SER A O 1 ATOM 3083 C CB . SER A 1 401 ? 45.779 -14.544 -26.789 1.00 8.17 ? 401 SER A CB 1 ATOM 3084 O OG . SER A 1 401 ? 45.108 -15.707 -27.240 0.50 5.83 ? 401 SER A OG 1 ATOM 3085 N N . GLY A 1 402 ? 46.911 -11.690 -27.319 1.00 7.44 ? 402 GLY A N 1 ATOM 3086 C CA . GLY A 1 402 ? 47.637 -10.521 -26.862 1.00 6.06 ? 402 GLY A CA 1 ATOM 3087 C C . GLY A 1 402 ? 46.852 -9.232 -27.013 1.00 6.79 ? 402 GLY A C 1 ATOM 3088 O O . GLY A 1 402 ? 46.804 -8.423 -26.087 1.00 6.82 ? 402 GLY A O 1 ATOM 3089 N N . MET A 1 403 ? 46.230 -9.025 -28.170 1.00 6.90 ? 403 MET A N 1 ATOM 3090 C CA . MET A 1 403 ? 45.469 -7.798 -28.365 1.00 7.03 ? 403 MET A CA 1 ATOM 3091 C C . MET A 1 403 ? 44.197 -7.776 -27.520 1.00 8.24 ? 403 MET A C 1 ATOM 3092 O O . MET A 1 403 ? 43.704 -6.706 -27.169 1.00 7.98 ? 403 MET A O 1 ATOM 3093 C CB . MET A 1 403 ? 45.160 -7.576 -29.850 1.00 7.77 ? 403 MET A CB 1 ATOM 3094 C CG . MET A 1 403 ? 46.405 -7.248 -30.685 1.00 7.85 ? 403 MET A CG 1 ATOM 3095 S SD . MET A 1 403 ? 47.625 -6.164 -29.856 1.00 9.35 ? 403 MET A SD 1 ATOM 3096 C CE . MET A 1 403 ? 46.711 -4.606 -29.757 1.00 9.34 ? 403 MET A CE 1 ATOM 3097 N N . LYS A 1 404 ? 43.667 -8.950 -27.185 1.00 6.93 ? 404 LYS A N 1 ATOM 3098 C CA . LYS A 1 404 ? 42.492 -9.003 -26.323 1.00 7.63 ? 404 LYS A CA 1 ATOM 3099 C C . LYS A 1 404 ? 42.937 -8.537 -24.935 1.00 8.08 ? 404 LYS A C 1 ATOM 3100 O O . LYS A 1 404 ? 42.188 -7.866 -24.228 1.00 7.34 ? 404 LYS A O 1 ATOM 3101 C CB . LYS A 1 404 ? 41.935 -10.426 -26.244 1.00 6.94 ? 404 LYS A CB 1 ATOM 3102 C CG . LYS A 1 404 ? 41.057 -10.810 -27.427 1.00 6.98 ? 404 LYS A CG 1 ATOM 3103 C CD . LYS A 1 404 ? 40.583 -12.247 -27.288 1.00 8.89 ? 404 LYS A CD 1 ATOM 3104 C CE . LYS A 1 404 ? 39.605 -12.624 -28.390 1.00 10.02 ? 404 LYS A CE 1 ATOM 3105 N NZ . LYS A 1 404 ? 39.203 -14.058 -28.276 1.00 11.01 ? 404 LYS A NZ 1 ATOM 3106 N N . LYS A 1 405 ? 44.162 -8.886 -24.547 1.00 7.58 ? 405 LYS A N 1 ATOM 3107 C CA . LYS A 1 405 ? 44.663 -8.467 -23.243 1.00 7.30 ? 405 LYS A CA 1 ATOM 3108 C C . LYS A 1 405 ? 44.835 -6.949 -23.248 1.00 7.17 ? 405 LYS A C 1 ATOM 3109 O O . LYS A 1 405 ? 44.566 -6.292 -22.245 1.00 7.39 ? 405 LYS A O 1 ATOM 3110 C CB . LYS A 1 405 ? 45.986 -9.172 -22.908 1.00 6.91 ? 405 LYS A CB 1 ATOM 3111 C CG . LYS A 1 405 ? 46.551 -8.825 -21.520 1.00 6.66 ? 405 LYS A CG 1 ATOM 3112 C CD . LYS A 1 405 ? 45.574 -9.141 -20.375 1.00 6.75 ? 405 LYS A CD 1 ATOM 3113 C CE . LYS A 1 405 ? 45.393 -10.644 -20.163 1.00 6.91 ? 405 LYS A CE 1 ATOM 3114 N NZ . LYS A 1 405 ? 44.442 -10.956 -19.043 1.00 8.39 ? 405 LYS A NZ 1 ATOM 3115 N N . ILE A 1 406 ? 45.282 -6.391 -24.373 1.00 6.72 ? 406 ILE A N 1 ATOM 3116 C CA . ILE A 1 406 ? 45.424 -4.938 -24.474 1.00 6.74 ? 406 ILE A CA 1 ATOM 3117 C C . ILE A 1 406 ? 44.022 -4.339 -24.313 1.00 7.58 ? 406 ILE A C 1 ATOM 3118 O O . ILE A 1 406 ? 43.845 -3.306 -23.667 1.00 7.29 ? 406 ILE A O 1 ATOM 3119 C CB . ILE A 1 406 ? 46.018 -4.507 -25.844 1.00 8.03 ? 406 ILE A CB 1 ATOM 3120 C CG1 . ILE A 1 406 ? 47.471 -4.973 -25.956 1.00 9.48 ? 406 ILE A CG1 1 ATOM 3121 C CG2 . ILE A 1 406 ? 45.949 -2.989 -25.995 1.00 8.47 ? 406 ILE A CG2 1 ATOM 3122 C CD1 . ILE A 1 406 ? 48.381 -4.457 -24.843 1.00 10.48 ? 406 ILE A CD1 1 ATOM 3123 N N . GLY A 1 407 ? 43.026 -4.999 -24.900 1.00 8.32 ? 407 GLY A N 1 ATOM 3124 C CA . GLY A 1 407 ? 41.656 -4.527 -24.771 1.00 7.77 ? 407 GLY A CA 1 ATOM 3125 C C . GLY A 1 407 ? 41.250 -4.484 -23.307 1.00 9.34 ? 407 GLY A C 1 ATOM 3126 O O . GLY A 1 407 ? 40.534 -3.576 -22.877 1.00 9.19 ? 407 GLY A O 1 ATOM 3127 N N . GLU A 1 408 ? 41.702 -5.469 -22.536 1.00 8.45 ? 408 GLU A N 1 ATOM 3128 C CA . GLU A 1 408 ? 41.397 -5.505 -21.110 1.00 9.08 ? 408 GLU A CA 1 ATOM 3129 C C . GLU A 1 408 ? 42.022 -4.298 -20.425 1.00 9.59 ? 408 GLU A C 1 ATOM 3130 O O . GLU A 1 408 ? 41.384 -3.652 -19.590 1.00 8.97 ? 408 GLU A O 1 ATOM 3131 C CB . GLU A 1 408 ? 41.935 -6.784 -20.467 1.00 8.71 ? 408 GLU A CB 1 ATOM 3132 C CG . GLU A 1 408 ? 41.095 -8.018 -20.736 1.00 11.62 ? 408 GLU A CG 1 ATOM 3133 C CD . GLU A 1 408 ? 41.504 -9.182 -19.852 1.00 12.48 ? 408 GLU A CD 1 ATOM 3134 O OE1 . GLU A 1 408 ? 42.156 -10.120 -20.353 1.00 13.67 ? 408 GLU A OE1 1 ATOM 3135 O OE2 . GLU A 1 408 ? 41.178 -9.148 -18.646 1.00 16.07 ? 408 GLU A OE2 1 ATOM 3136 N N . LEU A 1 409 ? 43.273 -4.002 -20.775 1.00 9.06 ? 409 LEU A N 1 ATOM 3137 C CA . LEU A 1 409 ? 43.968 -2.857 -20.198 1.00 8.11 ? 409 LEU A CA 1 ATOM 3138 C C . LEU A 1 409 ? 43.177 -1.586 -20.477 1.00 8.51 ? 409 LEU A C 1 ATOM 3139 O O . LEU A 1 409 ? 43.002 -0.747 -19.597 1.00 8.34 ? 409 LEU A O 1 ATOM 3140 C CB . LEU A 1 409 ? 45.373 -2.717 -20.795 1.00 7.78 ? 409 LEU A CB 1 ATOM 3141 C CG A LEU A 1 409 ? 46.529 -3.520 -20.188 0.50 7.92 ? 409 LEU A CG 1 ATOM 3142 C CG B LEU A 1 409 ? 46.322 -3.904 -20.495 0.50 7.88 ? 409 LEU A CG 1 ATOM 3143 C CD1 A LEU A 1 409 ? 46.195 -4.996 -20.125 0.50 9.36 ? 409 LEU A CD1 1 ATOM 3144 C CD1 B LEU A 1 409 ? 47.689 -3.646 -21.110 0.50 9.30 ? 409 LEU A CD1 1 ATOM 3145 C CD2 A LEU A 1 409 ? 47.775 -3.290 -21.032 0.50 6.90 ? 409 LEU A CD2 1 ATOM 3146 C CD2 B LEU A 1 409 ? 46.448 -4.164 -19.002 0.50 6.88 ? 409 LEU A CD2 1 ATOM 3147 N N . LEU A 1 410 ? 42.691 -1.457 -21.707 1.00 8.37 ? 410 LEU A N 1 ATOM 3148 C CA . LEU A 1 410 ? 41.924 -0.282 -22.106 1.00 8.35 ? 410 LEU A CA 1 ATOM 3149 C C . LEU A 1 410 ? 40.582 -0.174 -21.392 1.00 8.49 ? 410 LEU A C 1 ATOM 3150 O O . LEU A 1 410 ? 39.985 0.900 -21.350 1.00 10.20 ? 410 LEU A O 1 ATOM 3151 C CB . LEU A 1 410 ? 41.693 -0.300 -23.618 1.00 8.62 ? 410 LEU A CB 1 ATOM 3152 C CG . LEU A 1 410 ? 42.966 -0.186 -24.459 1.00 8.98 ? 410 LEU A CG 1 ATOM 3153 C CD1 . LEU A 1 410 ? 42.626 -0.304 -25.938 1.00 12.79 ? 410 LEU A CD1 1 ATOM 3154 C CD2 . LEU A 1 410 ? 43.648 1.145 -24.168 1.00 10.70 ? 410 LEU A CD2 1 ATOM 3155 N N . SER A 1 411 ? 40.116 -1.283 -20.826 1.00 6.79 ? 411 SER A N 1 ATOM 3156 C CA . SER A 1 411 ? 38.833 -1.308 -20.126 1.00 7.63 ? 411 SER A CA 1 ATOM 3157 C C . SER A 1 411 ? 38.956 -1.205 -18.602 1.00 9.26 ? 411 SER A C 1 ATOM 3158 O O . SER A 1 411 ? 37.949 -1.249 -17.889 1.00 10.54 ? 411 SER A O 1 ATOM 3159 C CB . SER A 1 411 ? 38.083 -2.593 -20.485 1.00 8.16 ? 411 SER A CB 1 ATOM 3160 O OG . SER A 1 411 ? 38.018 -2.758 -21.892 1.00 10.34 ? 411 SER A OG 1 ATOM 3161 N N . THR A 1 412 ? 40.181 -1.053 -18.106 1.00 9.79 ? 412 THR A N 1 ATOM 3162 C CA . THR A 1 412 ? 40.430 -0.963 -16.666 1.00 8.65 ? 412 THR A CA 1 ATOM 3163 C C . THR A 1 412 ? 40.074 0.391 -16.056 1.00 9.07 ? 412 THR A C 1 ATOM 3164 O O . THR A 1 412 ? 40.000 1.400 -16.757 1.00 9.28 ? 412 THR A O 1 ATOM 3165 C CB . THR A 1 412 ? 41.921 -1.201 -16.337 1.00 8.16 ? 412 THR A CB 1 ATOM 3166 O OG1 . THR A 1 412 ? 42.711 -0.199 -16.989 1.00 9.12 ? 412 THR A OG1 1 ATOM 3167 C CG2 . THR A 1 412 ? 42.373 -2.580 -16.797 1.00 7.99 ? 412 THR A CG2 1 ATOM 3168 N N . ASP A 1 413 ? 39.863 0.406 -14.741 1.00 9.74 ? 413 ASP A N 1 ATOM 3169 C CA . ASP A 1 413 ? 39.576 1.656 -14.040 1.00 9.08 ? 413 ASP A CA 1 ATOM 3170 C C . ASP A 1 413 ? 40.811 2.538 -14.223 1.00 10.14 ? 413 ASP A C 1 ATOM 3171 O O . ASP A 1 413 ? 40.713 3.758 -14.379 1.00 9.46 ? 413 ASP A O 1 ATOM 3172 C CB . ASP A 1 413 ? 39.377 1.420 -12.535 1.00 10.06 ? 413 ASP A CB 1 ATOM 3173 C CG . ASP A 1 413 ? 38.101 0.671 -12.211 1.00 11.65 ? 413 ASP A CG 1 ATOM 3174 O OD1 . ASP A 1 413 ? 37.293 0.414 -13.128 1.00 13.14 ? 413 ASP A OD1 1 ATOM 3175 O OD2 . ASP A 1 413 ? 37.907 0.346 -11.016 1.00 14.90 ? 413 ASP A OD2 1 ATOM 3176 N N . ALA A 1 414 ? 41.978 1.900 -14.202 1.00 9.90 ? 414 ALA A N 1 ATOM 3177 C CA . ALA A 1 414 ? 43.256 2.593 -14.338 1.00 10.30 ? 414 ALA A CA 1 ATOM 3178 C C . ALA A 1 414 ? 43.379 3.458 -15.589 1.00 10.26 ? 414 ALA A C 1 ATOM 3179 O O . ALA A 1 414 ? 43.962 4.538 -15.541 1.00 10.96 ? 414 ALA A O 1 ATOM 3180 C CB . ALA A 1 414 ? 44.403 1.580 -14.295 1.00 11.30 ? 414 ALA A CB 1 ATOM 3181 N N . LEU A 1 415 ? 42.831 3.001 -16.708 1.00 9.24 ? 415 LEU A N 1 ATOM 3182 C CA . LEU A 1 415 ? 42.939 3.781 -17.933 1.00 9.78 ? 415 LEU A CA 1 ATOM 3183 C C . LEU A 1 415 ? 41.734 4.672 -18.246 1.00 10.13 ? 415 LEU A C 1 ATOM 3184 O O . LEU A 1 415 ? 41.757 5.411 -19.225 1.00 10.14 ? 415 LEU A O 1 ATOM 3185 C CB . LEU A 1 415 ? 43.251 2.860 -19.123 1.00 13.26 ? 415 LEU A CB 1 ATOM 3186 C CG . LEU A 1 415 ? 44.554 2.045 -19.012 1.00 14.28 ? 415 LEU A CG 1 ATOM 3187 C CD1 . LEU A 1 415 ? 44.916 1.481 -20.377 1.00 17.21 ? 415 LEU A CD1 1 ATOM 3188 C CD2 . LEU A 1 415 ? 45.692 2.911 -18.493 1.00 15.94 ? 415 LEU A CD2 1 ATOM 3189 N N . LYS A 1 416 ? 40.699 4.629 -17.409 1.00 9.93 ? 416 LYS A N 1 ATOM 3190 C CA . LYS A 1 416 ? 39.512 5.459 -17.633 1.00 12.35 ? 416 LYS A CA 1 ATOM 3191 C C . LYS A 1 416 ? 39.823 6.943 -17.777 1.00 12.01 ? 416 LYS A C 1 ATOM 3192 O O . LYS A 1 416 ? 39.285 7.612 -18.666 1.00 12.31 ? 416 LYS A O 1 ATOM 3193 C CB . LYS A 1 416 ? 38.504 5.306 -16.486 1.00 15.02 ? 416 LYS A CB 1 ATOM 3194 C CG . LYS A 1 416 ? 38.054 3.902 -16.201 1.00 20.16 ? 416 LYS A CG 1 ATOM 3195 C CD . LYS A 1 416 ? 37.174 3.895 -14.959 1.00 23.30 ? 416 LYS A CD 1 ATOM 3196 C CE . LYS A 1 416 ? 35.705 4.021 -15.312 1.00 25.90 ? 416 LYS A CE 1 ATOM 3197 N NZ . LYS A 1 416 ? 35.165 2.720 -15.815 1.00 28.95 ? 416 LYS A NZ 1 ATOM 3198 N N . PRO A 1 417 ? 40.675 7.488 -16.889 1.00 12.25 ? 417 PRO A N 1 ATOM 3199 C CA . PRO A 1 417 ? 41.019 8.913 -16.954 1.00 12.38 ? 417 PRO A CA 1 ATOM 3200 C C . PRO A 1 417 ? 41.655 9.364 -18.256 1.00 13.05 ? 417 PRO A C 1 ATOM 3201 O O . PRO A 1 417 ? 41.802 10.564 -18.496 1.00 13.28 ? 417 PRO A O 1 ATOM 3202 C CB . PRO A 1 417 ? 41.972 9.098 -15.771 1.00 13.35 ? 417 PRO A CB 1 ATOM 3203 C CG . PRO A 1 417 ? 41.538 8.052 -14.805 1.00 13.65 ? 417 PRO A CG 1 ATOM 3204 C CD . PRO A 1 417 ? 41.305 6.860 -15.713 1.00 12.41 ? 417 PRO A CD 1 ATOM 3205 N N . TYR A 1 418 ? 42.029 8.410 -19.099 1.00 11.49 ? 418 TYR A N 1 ATOM 3206 C CA . TYR A 1 418 ? 42.684 8.752 -20.349 1.00 11.46 ? 418 TYR A CA 1 ATOM 3207 C C . TYR A 1 418 ? 41.798 8.648 -21.586 1.00 12.41 ? 418 TYR A C 1 ATOM 3208 O O . TYR A 1 418 ? 42.267 8.789 -22.715 1.00 11.48 ? 418 TYR A O 1 ATOM 3209 C CB . TYR A 1 418 ? 43.965 7.923 -20.477 1.00 11.28 ? 418 TYR A CB 1 ATOM 3210 C CG . TYR A 1 418 ? 44.833 8.098 -19.249 1.00 10.80 ? 418 TYR A CG 1 ATOM 3211 C CD1 . TYR A 1 418 ? 44.810 7.165 -18.212 1.00 9.82 ? 418 TYR A CD1 1 ATOM 3212 C CD2 . TYR A 1 418 ? 45.588 9.257 -19.071 1.00 11.58 ? 418 TYR A CD2 1 ATOM 3213 C CE1 . TYR A 1 418 ? 45.512 7.385 -17.027 1.00 11.04 ? 418 TYR A CE1 1 ATOM 3214 C CE2 . TYR A 1 418 ? 46.290 9.489 -17.891 1.00 12.52 ? 418 TYR A CE2 1 ATOM 3215 C CZ . TYR A 1 418 ? 46.245 8.550 -16.872 1.00 12.24 ? 418 TYR A CZ 1 ATOM 3216 O OH . TYR A 1 418 ? 46.917 8.784 -15.692 1.00 15.10 ? 418 TYR A OH 1 ATOM 3217 N N . LYS A 1 419 ? 40.508 8.416 -21.362 1.00 12.29 ? 419 LYS A N 1 ATOM 3218 C CA . LYS A 1 419 ? 39.540 8.351 -22.449 1.00 14.01 ? 419 LYS A CA 1 ATOM 3219 C C . LYS A 1 419 ? 39.062 9.781 -22.682 1.00 15.37 ? 419 LYS A C 1 ATOM 3220 O O . LYS A 1 419 ? 39.127 10.615 -21.779 1.00 15.70 ? 419 LYS A O 1 ATOM 3221 C CB . LYS A 1 419 ? 38.331 7.496 -22.062 1.00 13.75 ? 419 LYS A CB 1 ATOM 3222 C CG . LYS A 1 419 ? 38.572 6.000 -22.015 1.00 13.27 ? 419 LYS A CG 1 ATOM 3223 C CD . LYS A 1 419 ? 37.253 5.264 -21.832 1.00 13.54 ? 419 LYS A CD 1 ATOM 3224 C CE . LYS A 1 419 ? 37.431 3.755 -21.920 1.00 13.89 ? 419 LYS A CE 1 ATOM 3225 N NZ . LYS A 1 419 ? 36.115 3.057 -21.923 1.00 16.10 ? 419 LYS A NZ 1 ATOM 3226 N N . VAL A 1 420 ? 38.588 10.068 -23.889 1.00 16.32 ? 420 VAL A N 1 ATOM 3227 C CA . VAL A 1 420 ? 38.077 11.400 -24.191 1.00 19.46 ? 420 VAL A CA 1 ATOM 3228 C C . VAL A 1 420 ? 36.580 11.415 -23.892 1.00 21.45 ? 420 VAL A C 1 ATOM 3229 O O . VAL A 1 420 ? 36.001 12.460 -23.594 1.00 21.61 ? 420 VAL A O 1 ATOM 3230 C CB . VAL A 1 420 ? 38.306 11.767 -25.674 1.00 20.28 ? 420 VAL A CB 1 ATOM 3231 C CG1 . VAL A 1 420 ? 37.641 13.101 -25.990 1.00 21.78 ? 420 VAL A CG1 1 ATOM 3232 C CG2 . VAL A 1 420 ? 39.796 11.847 -25.962 1.00 21.22 ? 420 VAL A CG2 1 ATOM 3233 N N . GLU A 1 421 ? 35.968 10.236 -23.967 1.00 23.51 ? 421 GLU A N 1 ATOM 3234 C CA . GLU A 1 421 ? 34.540 10.063 -23.714 1.00 26.90 ? 421 GLU A CA 1 ATOM 3235 C C . GLU A 1 421 ? 34.351 8.804 -22.874 1.00 27.44 ? 421 GLU A C 1 ATOM 3236 O O . GLU A 1 421 ? 35.030 7.803 -23.096 1.00 26.16 ? 421 GLU A O 1 ATOM 3237 C CB . GLU A 1 421 ? 33.791 9.889 -25.034 1.00 29.70 ? 421 GLU A CB 1 ATOM 3238 C CG . GLU A 1 421 ? 34.203 10.856 -26.127 1.00 34.93 ? 421 GLU A CG 1 ATOM 3239 C CD . GLU A 1 421 ? 33.563 10.520 -27.459 1.00 37.78 ? 421 GLU A CD 1 ATOM 3240 O OE1 . GLU A 1 421 ? 32.316 10.462 -27.521 1.00 40.18 ? 421 GLU A OE1 1 ATOM 3241 O OE2 . GLU A 1 421 ? 34.304 10.311 -28.444 1.00 40.35 ? 421 GLU A OE2 1 ATOM 3242 N N . ASP A 1 422 ? 33.427 8.842 -21.921 1.00 28.61 ? 422 ASP A N 1 ATOM 3243 C CA . ASP A 1 422 ? 33.185 7.678 -21.074 1.00 29.66 ? 422 ASP A CA 1 ATOM 3244 C C . ASP A 1 422 ? 32.247 6.680 -21.754 1.00 29.63 ? 422 ASP A C 1 ATOM 3245 O O . ASP A 1 422 ? 31.075 6.562 -21.393 1.00 30.98 ? 422 ASP A O 1 ATOM 3246 C CB . ASP A 1 422 ? 32.613 8.119 -19.720 1.00 30.89 ? 422 ASP A CB 1 ATOM 3247 C CG A ASP A 1 422 ? 31.264 8.799 -19.846 0.50 31.62 ? 422 ASP A CG 1 ATOM 3248 C CG B ASP A 1 422 ? 32.541 6.918 -18.765 0.50 32.31 ? 422 ASP A CG 1 ATOM 3249 O OD1 A ASP A 1 422 ? 31.079 9.587 -20.797 0.50 32.63 ? 422 ASP A OD1 1 ATOM 3250 O OD1 B ASP A 1 422 ? 33.027 5.824 -19.122 0.50 33.34 ? 422 ASP A OD1 1 ATOM 3251 O OD2 A ASP A 1 422 ? 30.392 8.553 -18.985 0.50 31.76 ? 422 ASP A OD2 1 ATOM 3252 O OD2 B ASP A 1 422 ? 32.012 7.100 -17.650 0.50 32.45 ? 422 ASP A OD2 1 ATOM 3253 N N . LEU A 1 423 ? 32.774 5.968 -22.748 1.00 27.53 ? 423 LEU A N 1 ATOM 3254 C CA . LEU A 1 423 ? 32.002 4.971 -23.483 1.00 25.15 ? 423 LEU A CA 1 ATOM 3255 C C . LEU A 1 423 ? 32.303 3.583 -22.920 1.00 23.49 ? 423 LEU A C 1 ATOM 3256 O O . LEU A 1 423 ? 33.334 3.379 -22.280 1.00 23.00 ? 423 LEU A O 1 ATOM 3257 C CB . LEU A 1 423 ? 32.348 5.024 -24.975 1.00 25.31 ? 423 LEU A CB 1 ATOM 3258 C CG . LEU A 1 423 ? 32.090 6.361 -25.679 1.00 26.23 ? 423 LEU A CG 1 ATOM 3259 C CD1 . LEU A 1 423 ? 32.442 6.242 -27.152 1.00 25.22 ? 423 LEU A CD1 1 ATOM 3260 C CD2 . LEU A 1 423 ? 30.632 6.758 -25.513 1.00 26.76 ? 423 LEU A CD2 1 ATOM 3261 N N . PRO A 1 424 ? 31.408 2.610 -23.154 1.00 22.21 ? 424 PRO A N 1 ATOM 3262 C CA . PRO A 1 424 ? 31.607 1.246 -22.650 1.00 20.69 ? 424 PRO A CA 1 ATOM 3263 C C . PRO A 1 424 ? 32.760 0.481 -23.299 1.00 19.52 ? 424 PRO A C 1 ATOM 3264 O O . PRO A 1 424 ? 33.181 0.792 -24.413 1.00 18.93 ? 424 PRO A O 1 ATOM 3265 C CB . PRO A 1 424 ? 30.257 0.587 -22.914 1.00 21.15 ? 424 PRO A CB 1 ATOM 3266 C CG . PRO A 1 424 ? 29.816 1.254 -24.175 1.00 22.82 ? 424 PRO A CG 1 ATOM 3267 C CD . PRO A 1 424 ? 30.146 2.708 -23.910 1.00 21.23 ? 424 PRO A CD 1 ATOM 3268 N N . GLY A 1 425 ? 33.263 -0.521 -22.584 1.00 18.06 ? 425 GLY A N 1 ATOM 3269 C CA . GLY A 1 425 ? 34.349 -1.338 -23.096 1.00 16.44 ? 425 GLY A CA 1 ATOM 3270 C C . GLY A 1 425 ? 35.629 -0.595 -23.425 1.00 15.17 ? 425 GLY A C 1 ATOM 3271 O O . GLY A 1 425 ? 36.116 0.208 -22.628 1.00 15.57 ? 425 GLY A O 1 ATOM 3272 N N . VAL A 1 426 ? 36.172 -0.869 -24.608 1.00 13.05 ? 426 VAL A N 1 ATOM 3273 C CA . VAL A 1 426 ? 37.413 -0.251 -25.060 1.00 12.33 ? 426 VAL A CA 1 ATOM 3274 C C . VAL A 1 426 ? 37.181 1.058 -25.806 1.00 11.77 ? 426 VAL A C 1 ATOM 3275 O O . VAL A 1 426 ? 38.127 1.685 -26.274 1.00 12.66 ? 426 VAL A O 1 ATOM 3276 C CB . VAL A 1 426 ? 38.194 -1.193 -26.006 1.00 10.86 ? 426 VAL A CB 1 ATOM 3277 C CG1 . VAL A 1 426 ? 38.423 -2.529 -25.332 1.00 10.14 ? 426 VAL A CG1 1 ATOM 3278 C CG2 . VAL A 1 426 ? 37.432 -1.375 -27.314 1.00 10.29 ? 426 VAL A CG2 1 ATOM 3279 N N . GLU A 1 427 ? 35.923 1.467 -25.916 1.00 14.33 ? 427 GLU A N 1 ATOM 3280 C CA . GLU A 1 427 ? 35.589 2.693 -26.631 1.00 14.89 ? 427 GLU A CA 1 ATOM 3281 C C . GLU A 1 427 ? 35.751 3.951 -25.788 1.00 14.72 ? 427 GLU A C 1 ATOM 3282 O O . GLU A 1 427 ? 35.752 3.893 -24.559 1.00 14.97 ? 427 GLU A O 1 ATOM 3283 C CB . GLU A 1 427 ? 34.155 2.608 -27.157 1.00 16.86 ? 427 GLU A CB 1 ATOM 3284 C CG . GLU A 1 427 ? 33.961 1.562 -28.243 1.00 20.89 ? 427 GLU A CG 1 ATOM 3285 C CD . GLU A 1 427 ? 32.539 1.521 -28.763 1.00 24.67 ? 427 GLU A CD 1 ATOM 3286 O OE1 . GLU A 1 427 ? 31.680 0.882 -28.120 1.00 24.20 ? 427 GLU A OE1 1 ATOM 3287 O OE2 . GLU A 1 427 ? 32.279 2.144 -29.814 1.00 26.95 ? 427 GLU A OE2 1 ATOM 3288 N N . GLY A 1 428 ? 35.896 5.091 -26.459 1.00 14.15 ? 428 GLY A N 1 ATOM 3289 C CA . GLY A 1 428 ? 36.037 6.346 -25.742 1.00 14.04 ? 428 GLY A CA 1 ATOM 3290 C C . GLY A 1 428 ? 37.393 7.016 -25.854 1.00 13.88 ? 428 GLY A C 1 ATOM 3291 O O . GLY A 1 428 ? 37.534 8.189 -25.507 1.00 14.48 ? 428 GLY A O 1 ATOM 3292 N N . PHE A 1 429 ? 38.394 6.282 -26.327 1.00 13.41 ? 429 PHE A N 1 ATOM 3293 C CA . PHE A 1 429 ? 39.731 6.844 -26.475 1.00 13.90 ? 429 PHE A CA 1 ATOM 3294 C C . PHE A 1 429 ? 39.904 7.540 -27.813 1.00 14.10 ? 429 PHE A C 1 ATOM 3295 O O . PHE A 1 429 ? 39.211 7.236 -28.782 1.00 16.10 ? 429 PHE A O 1 ATOM 3296 C CB . PHE A 1 429 ? 40.813 5.758 -26.396 1.00 11.93 ? 429 PHE A CB 1 ATOM 3297 C CG . PHE A 1 429 ? 40.914 5.078 -25.065 1.00 11.38 ? 429 PHE A CG 1 ATOM 3298 C CD1 . PHE A 1 429 ? 40.231 3.891 -24.818 1.00 11.71 ? 429 PHE A CD1 1 ATOM 3299 C CD2 . PHE A 1 429 ? 41.712 5.612 -24.062 1.00 10.75 ? 429 PHE A CD2 1 ATOM 3300 C CE1 . PHE A 1 429 ? 40.347 3.247 -23.591 1.00 11.07 ? 429 PHE A CE1 1 ATOM 3301 C CE2 . PHE A 1 429 ? 41.833 4.976 -22.832 1.00 11.83 ? 429 PHE A CE2 1 ATOM 3302 C CZ . PHE A 1 429 ? 41.151 3.792 -22.596 1.00 11.24 ? 429 PHE A CZ 1 ATOM 3303 N N . ASN A 1 430 ? 40.840 8.479 -27.852 1.00 14.84 ? 430 ASN A N 1 ATOM 3304 C CA . ASN A 1 430 ? 41.179 9.166 -29.086 1.00 15.65 ? 430 ASN A CA 1 ATOM 3305 C C . ASN A 1 430 ? 42.322 8.274 -29.567 1.00 15.29 ? 430 ASN A C 1 ATOM 3306 O O . ASN A 1 430 ? 43.391 8.248 -28.957 1.00 15.12 ? 430 ASN A O 1 ATOM 3307 C CB . ASN A 1 430 ? 41.685 10.579 -28.792 1.00 17.40 ? 430 ASN A CB 1 ATOM 3308 C CG . ASN A 1 430 ? 42.053 11.346 -30.049 1.00 20.04 ? 430 ASN A CG 1 ATOM 3309 O OD1 . ASN A 1 430 ? 42.453 12.509 -29.982 1.00 21.77 ? 430 ASN A OD1 1 ATOM 3310 N ND2 . ASN A 1 430 ? 41.921 10.700 -31.203 1.00 20.37 ? 430 ASN A ND2 1 ATOM 3311 N N . ILE A 1 431 ? 42.089 7.526 -30.639 1.00 14.12 ? 431 ILE A N 1 ATOM 3312 C CA . ILE A 1 431 ? 43.096 6.604 -31.155 1.00 14.48 ? 431 ILE A CA 1 ATOM 3313 C C . ILE A 1 431 ? 43.911 7.129 -32.329 1.00 15.06 ? 431 ILE A C 1 ATOM 3314 O O . ILE A 1 431 ? 43.366 7.723 -33.260 1.00 16.94 ? 431 ILE A O 1 ATOM 3315 C CB . ILE A 1 431 ? 42.436 5.268 -31.601 1.00 14.66 ? 431 ILE A CB 1 ATOM 3316 C CG1 . ILE A 1 431 ? 41.679 4.635 -30.428 1.00 16.28 ? 431 ILE A CG1 1 ATOM 3317 C CG2 . ILE A 1 431 ? 43.490 4.315 -32.151 1.00 14.98 ? 431 ILE A CG2 1 ATOM 3318 C CD1 . ILE A 1 431 ? 42.548 4.278 -29.239 1.00 15.17 ? 431 ILE A CD1 1 ATOM 3319 N N . LEU A 1 432 ? 45.221 6.910 -32.276 1.00 14.30 ? 432 LEU A N 1 ATOM 3320 C CA . LEU A 1 432 ? 46.105 7.306 -33.368 1.00 14.39 ? 432 LEU A CA 1 ATOM 3321 C C . LEU A 1 432 ? 46.380 6.022 -34.144 1.00 14.88 ? 432 LEU A C 1 ATOM 3322 O O . LEU A 1 432 ? 47.087 5.140 -33.660 1.00 15.60 ? 432 LEU A O 1 ATOM 3323 C CB . LEU A 1 432 ? 47.429 7.869 -32.839 1.00 14.43 ? 432 LEU A CB 1 ATOM 3324 C CG . LEU A 1 432 ? 48.441 8.264 -33.924 1.00 15.20 ? 432 LEU A CG 1 ATOM 3325 C CD1 . LEU A 1 432 ? 47.986 9.557 -34.595 1.00 16.20 ? 432 LEU A CD1 1 ATOM 3326 C CD2 . LEU A 1 432 ? 49.825 8.446 -33.314 1.00 14.86 ? 432 LEU A CD2 1 ATOM 3327 N N . GLY A 1 433 ? 45.812 5.907 -35.339 1.00 14.15 ? 433 GLY A N 1 ATOM 3328 C CA . GLY A 1 433 ? 46.029 4.706 -36.123 1.00 13.46 ? 433 GLY A CA 1 ATOM 3329 C C . GLY A 1 433 ? 44.849 3.753 -36.085 1.00 11.51 ? 433 GLY A C 1 ATOM 3330 O O . GLY A 1 433 ? 43.720 4.155 -35.808 1.00 12.39 ? 433 GLY A O 1 ATOM 3331 N N . ILE A 1 434 ? 45.116 2.478 -36.347 1.00 10.25 ? 434 ILE A N 1 ATOM 3332 C CA . ILE A 1 434 ? 44.066 1.463 -36.378 1.00 11.09 ? 434 ILE A CA 1 ATOM 3333 C C . ILE A 1 434 ? 43.567 1.065 -34.993 1.00 10.66 ? 434 ILE A C 1 ATOM 3334 O O . ILE A 1 434 ? 44.335 0.608 -34.152 1.00 11.04 ? 434 ILE A O 1 ATOM 3335 C CB . ILE A 1 434 ? 44.557 0.205 -37.116 1.00 12.19 ? 434 ILE A CB 1 ATOM 3336 C CG1 . ILE A 1 434 ? 45.018 0.594 -38.525 1.00 11.98 ? 434 ILE A CG1 1 ATOM 3337 C CG2 . ILE A 1 434 ? 43.442 -0.841 -37.170 1.00 11.92 ? 434 ILE A CG2 1 ATOM 3338 C CD1 . ILE A 1 434 ? 45.690 -0.518 -39.285 1.00 12.15 ? 434 ILE A CD1 1 ATOM 3339 N N . PRO A 1 435 ? 42.259 1.233 -34.743 1.00 11.48 ? 435 PRO A N 1 ATOM 3340 C CA . PRO A 1 435 ? 41.669 0.886 -33.447 1.00 11.13 ? 435 PRO A CA 1 ATOM 3341 C C . PRO A 1 435 ? 41.332 -0.599 -33.310 1.00 9.89 ? 435 PRO A C 1 ATOM 3342 O O . PRO A 1 435 ? 41.226 -1.318 -34.304 1.00 10.19 ? 435 PRO A O 1 ATOM 3343 C CB . PRO A 1 435 ? 40.421 1.756 -33.407 1.00 12.20 ? 435 PRO A CB 1 ATOM 3344 C CG . PRO A 1 435 ? 39.970 1.706 -34.837 1.00 12.34 ? 435 PRO A CG 1 ATOM 3345 C CD . PRO A 1 435 ? 41.267 1.903 -35.607 1.00 12.90 ? 435 PRO A CD 1 ATOM 3346 N N . LEU A 1 436 ? 41.174 -1.056 -32.072 1.00 9.65 ? 436 LEU A N 1 ATOM 3347 C CA . LEU A 1 436 ? 40.816 -2.446 -31.819 1.00 9.54 ? 436 LEU A CA 1 ATOM 3348 C C . LEU A 1 436 ? 39.368 -2.660 -32.210 1.00 9.84 ? 436 LEU A C 1 ATOM 3349 O O . LEU A 1 436 ? 38.585 -1.711 -32.260 1.00 10.28 ? 436 LEU A O 1 ATOM 3350 C CB . LEU A 1 436 ? 40.910 -2.787 -30.330 1.00 11.62 ? 436 LEU A CB 1 ATOM 3351 C CG . LEU A 1 436 ? 42.230 -3.008 -29.604 1.00 13.12 ? 436 LEU A CG 1 ATOM 3352 C CD1 . LEU A 1 436 ? 41.919 -3.372 -28.153 1.00 14.34 ? 436 LEU A CD1 1 ATOM 3353 C CD2 . LEU A 1 436 ? 43.020 -4.124 -30.274 1.00 14.82 ? 436 LEU A CD2 1 ATOM 3354 N N . PRO A 1 437 ? 38.996 -3.911 -32.516 1.00 10.22 ? 437 PRO A N 1 ATOM 3355 C CA . PRO A 1 437 ? 37.602 -4.178 -32.872 1.00 10.40 ? 437 PRO A CA 1 ATOM 3356 C C . PRO A 1 437 ? 36.832 -3.875 -31.581 1.00 10.20 ? 437 PRO A C 1 ATOM 3357 O O . PRO A 1 437 ? 37.357 -4.102 -30.490 1.00 10.11 ? 437 PRO A O 1 ATOM 3358 C CB . PRO A 1 437 ? 37.611 -5.670 -33.191 1.00 11.38 ? 437 PRO A CB 1 ATOM 3359 C CG . PRO A 1 437 ? 38.986 -5.884 -33.763 1.00 12.17 ? 437 PRO A CG 1 ATOM 3360 C CD . PRO A 1 437 ? 39.857 -5.069 -32.823 1.00 10.27 ? 437 PRO A CD 1 ATOM 3361 N N . LYS A 1 438 ? 35.612 -3.360 -31.685 1.00 11.73 ? 438 LYS A N 1 ATOM 3362 C CA . LYS A 1 438 ? 34.829 -3.042 -30.488 1.00 12.06 ? 438 LYS A CA 1 ATOM 3363 C C . LYS A 1 438 ? 34.461 -4.305 -29.708 1.00 11.11 ? 438 LYS A C 1 ATOM 3364 O O . LYS A 1 438 ? 34.583 -4.355 -28.478 1.00 10.28 ? 438 LYS A O 1 ATOM 3365 C CB . LYS A 1 438 ? 33.550 -2.299 -30.878 1.00 14.47 ? 438 LYS A CB 1 ATOM 3366 C CG . LYS A 1 438 ? 33.783 -1.068 -31.738 1.00 19.07 ? 438 LYS A CG 1 ATOM 3367 C CD . LYS A 1 438 ? 32.465 -0.470 -32.208 1.00 21.89 ? 438 LYS A CD 1 ATOM 3368 C CE . LYS A 1 438 ? 32.692 0.650 -33.211 1.00 25.33 ? 438 LYS A CE 1 ATOM 3369 N NZ . LYS A 1 438 ? 33.514 1.754 -32.641 1.00 28.06 ? 438 LYS A NZ 1 ATOM 3370 N N . ASP A 1 439 ? 34.002 -5.316 -30.438 1.00 10.46 ? 439 ASP A N 1 ATOM 3371 C CA . ASP A 1 439 ? 33.595 -6.598 -29.864 1.00 10.40 ? 439 ASP A CA 1 ATOM 3372 C C . ASP A 1 439 ? 34.829 -7.404 -29.464 1.00 9.60 ? 439 ASP A C 1 ATOM 3373 O O . ASP A 1 439 ? 35.550 -7.907 -30.324 1.00 10.99 ? 439 ASP A O 1 ATOM 3374 C CB . ASP A 1 439 ? 32.780 -7.370 -30.904 1.00 10.82 ? 439 ASP A CB 1 ATOM 3375 C CG . ASP A 1 439 ? 32.230 -8.679 -30.376 1.00 11.42 ? 439 ASP A CG 1 ATOM 3376 O OD1 . ASP A 1 439 ? 32.666 -9.136 -29.299 1.00 10.49 ? 439 ASP A OD1 1 ATOM 3377 O OD2 . ASP A 1 439 ? 31.358 -9.260 -31.056 1.00 12.11 ? 439 ASP A OD2 1 ATOM 3378 N N . GLN A 1 440 ? 35.061 -7.541 -28.161 1.00 9.60 ? 440 GLN A N 1 ATOM 3379 C CA . GLN A 1 440 ? 36.231 -8.270 -27.679 1.00 9.66 ? 440 GLN A CA 1 ATOM 3380 C C . GLN A 1 440 ? 36.154 -9.788 -27.847 1.00 9.88 ? 440 GLN A C 1 ATOM 3381 O O . GLN A 1 440 ? 37.101 -10.497 -27.508 1.00 11.48 ? 440 GLN A O 1 ATOM 3382 C CB . GLN A 1 440 ? 36.504 -7.915 -26.212 1.00 9.29 ? 440 GLN A CB 1 ATOM 3383 C CG . GLN A 1 440 ? 36.766 -6.426 -25.985 1.00 9.56 ? 440 GLN A CG 1 ATOM 3384 C CD . GLN A 1 440 ? 37.926 -5.898 -26.819 1.00 9.82 ? 440 GLN A CD 1 ATOM 3385 O OE1 . GLN A 1 440 ? 39.090 -6.205 -26.553 1.00 8.65 ? 440 GLN A OE1 1 ATOM 3386 N NE2 . GLN A 1 440 ? 37.608 -5.107 -27.840 1.00 10.89 ? 440 GLN A NE2 1 ATOM 3387 N N . THR A 1 441 ? 35.037 -10.285 -28.375 1.00 10.11 ? 441 THR A N 1 ATOM 3388 C CA . THR A 1 441 ? 34.875 -11.720 -28.592 1.00 10.27 ? 441 THR A CA 1 ATOM 3389 C C . THR A 1 441 ? 34.885 -12.065 -30.086 1.00 11.26 ? 441 THR A C 1 ATOM 3390 O O . THR A 1 441 ? 34.722 -13.227 -30.461 1.00 13.41 ? 441 THR A O 1 ATOM 3391 C CB . THR A 1 441 ? 33.553 -12.243 -27.975 1.00 11.04 ? 441 THR A CB 1 ATOM 3392 O OG1 . THR A 1 441 ? 32.436 -11.646 -28.652 1.00 10.56 ? 441 THR A OG1 1 ATOM 3393 C CG2 . THR A 1 441 ? 33.487 -11.908 -26.490 1.00 11.02 ? 441 THR A CG2 1 ATOM 3394 N N . ASP A 1 442 ? 35.078 -11.059 -30.934 1.00 10.57 ? 442 ASP A N 1 ATOM 3395 C CA . ASP A 1 442 ? 35.101 -11.274 -32.384 1.00 11.33 ? 442 ASP A CA 1 ATOM 3396 C C . ASP A 1 442 ? 36.510 -11.658 -32.836 1.00 10.00 ? 442 ASP A C 1 ATOM 3397 O O . ASP A 1 442 ? 37.291 -10.809 -33.270 1.00 10.32 ? 442 ASP A O 1 ATOM 3398 C CB . ASP A 1 442 ? 34.653 -10.004 -33.117 1.00 12.41 ? 442 ASP A CB 1 ATOM 3399 C CG . ASP A 1 442 ? 34.379 -10.240 -34.596 1.00 14.39 ? 442 ASP A CG 1 ATOM 3400 O OD1 . ASP A 1 442 ? 34.906 -11.221 -35.161 1.00 15.93 ? 442 ASP A OD1 1 ATOM 3401 O OD2 . ASP A 1 442 ? 33.644 -9.429 -35.197 1.00 16.40 ? 442 ASP A OD2 1 ATOM 3402 N N . ASP A 1 443 ? 36.826 -12.945 -32.740 1.00 10.67 ? 443 ASP A N 1 ATOM 3403 C CA . ASP A 1 443 ? 38.142 -13.445 -33.117 1.00 11.39 ? 443 ASP A CA 1 ATOM 3404 C C . ASP A 1 443 ? 38.546 -13.109 -34.549 1.00 9.70 ? 443 ASP A C 1 ATOM 3405 O O . ASP A 1 443 ? 39.673 -12.683 -34.796 1.00 9.50 ? 443 ASP A O 1 ATOM 3406 C CB . ASP A 1 443 ? 38.206 -14.963 -32.905 1.00 12.58 ? 443 ASP A CB 1 ATOM 3407 C CG . ASP A 1 443 ? 38.175 -15.349 -31.435 1.00 14.66 ? 443 ASP A CG 1 ATOM 3408 O OD1 . ASP A 1 443 ? 37.963 -14.459 -30.587 1.00 14.80 ? 443 ASP A OD1 1 ATOM 3409 O OD2 . ASP A 1 443 ? 38.358 -16.547 -31.129 1.00 18.89 ? 443 ASP A OD2 1 ATOM 3410 N N . ALA A 1 444 ? 37.633 -13.298 -35.497 1.00 9.86 ? 444 ALA A N 1 ATOM 3411 C CA . ALA A 1 444 ? 37.942 -13.008 -36.892 1.00 9.64 ? 444 ALA A CA 1 ATOM 3412 C C . ALA A 1 444 ? 38.349 -11.550 -37.084 1.00 9.87 ? 444 ALA A C 1 ATOM 3413 O O . ALA A 1 444 ? 39.254 -11.246 -37.866 1.00 10.94 ? 444 ALA A O 1 ATOM 3414 C CB . ALA A 1 444 ? 36.748 -13.340 -37.775 1.00 11.65 ? 444 ALA A CB 1 ATOM 3415 N N . ALA A 1 445 ? 37.680 -10.649 -36.371 1.00 9.72 ? 445 ALA A N 1 ATOM 3416 C CA . ALA A 1 445 ? 37.996 -9.232 -36.471 1.00 7.93 ? 445 ALA A CA 1 ATOM 3417 C C . ALA A 1 445 ? 39.390 -8.974 -35.903 1.00 9.24 ? 445 ALA A C 1 ATOM 3418 O O . ALA A 1 445 ? 40.134 -8.140 -36.423 1.00 9.25 ? 445 ALA A O 1 ATOM 3419 C CB . ALA A 1 445 ? 36.961 -8.405 -35.720 1.00 9.26 ? 445 ALA A CB 1 ATOM 3420 N N . PHE A 1 446 ? 39.741 -9.690 -34.839 1.00 8.58 ? 446 PHE A N 1 ATOM 3421 C CA . PHE A 1 446 ? 41.056 -9.521 -34.235 1.00 8.17 ? 446 PHE A CA 1 ATOM 3422 C C . PHE A 1 446 ? 42.148 -10.076 -35.137 1.00 7.47 ? 446 PHE A C 1 ATOM 3423 O O . PHE A 1 446 ? 43.250 -9.545 -35.169 1.00 7.27 ? 446 PHE A O 1 ATOM 3424 C CB . PHE A 1 446 ? 41.124 -10.181 -32.852 1.00 8.09 ? 446 PHE A CB 1 ATOM 3425 C CG . PHE A 1 446 ? 40.672 -9.283 -31.733 1.00 7.93 ? 446 PHE A CG 1 ATOM 3426 C CD1 . PHE A 1 446 ? 39.321 -9.059 -31.502 1.00 8.44 ? 446 PHE A CD1 1 ATOM 3427 C CD2 . PHE A 1 446 ? 41.605 -8.636 -30.926 1.00 6.91 ? 446 PHE A CD2 1 ATOM 3428 C CE1 . PHE A 1 446 ? 38.903 -8.205 -30.486 1.00 8.70 ? 446 PHE A CE1 1 ATOM 3429 C CE2 . PHE A 1 446 ? 41.199 -7.781 -29.907 1.00 7.39 ? 446 PHE A CE2 1 ATOM 3430 C CZ . PHE A 1 446 ? 39.845 -7.563 -29.685 1.00 7.95 ? 446 PHE A CZ 1 ATOM 3431 N N . GLU A 1 447 ? 41.848 -11.144 -35.872 1.00 7.63 ? 447 GLU A N 1 ATOM 3432 C CA . GLU A 1 447 ? 42.842 -11.705 -36.781 1.00 8.71 ? 447 GLU A CA 1 ATOM 3433 C C . GLU A 1 447 ? 43.133 -10.689 -37.880 1.00 9.46 ? 447 GLU A C 1 ATOM 3434 O O . GLU A 1 447 ? 44.284 -10.498 -38.273 1.00 9.11 ? 447 GLU A O 1 ATOM 3435 C CB . GLU A 1 447 ? 42.344 -13.023 -37.387 1.00 9.26 ? 447 GLU A CB 1 ATOM 3436 C CG . GLU A 1 447 ? 42.332 -14.175 -36.396 1.00 10.95 ? 447 GLU A CG 1 ATOM 3437 C CD . GLU A 1 447 ? 42.035 -15.508 -37.050 1.00 14.49 ? 447 GLU A CD 1 ATOM 3438 O OE1 . GLU A 1 447 ? 41.995 -15.564 -38.302 1.00 15.15 ? 447 GLU A OE1 1 ATOM 3439 O OE2 . GLU A 1 447 ? 41.853 -16.503 -36.314 1.00 16.12 ? 447 GLU A OE2 1 ATOM 3440 N N . THR A 1 448 ? 42.087 -10.031 -38.373 1.00 9.56 ? 448 THR A N 1 ATOM 3441 C CA . THR A 1 448 ? 42.257 -9.022 -39.409 1.00 10.24 ? 448 THR A CA 1 ATOM 3442 C C . THR A 1 448 ? 43.057 -7.845 -38.854 1.00 9.37 ? 448 THR A C 1 ATOM 3443 O O . THR A 1 448 ? 43.930 -7.304 -39.532 1.00 9.51 ? 448 THR A O 1 ATOM 3444 C CB . THR A 1 448 ? 40.898 -8.524 -39.925 1.00 10.65 ? 448 THR A CB 1 ATOM 3445 O OG1 . THR A 1 448 ? 40.248 -9.588 -40.631 1.00 13.29 ? 448 THR A OG1 1 ATOM 3446 C CG2 . THR A 1 448 ? 41.081 -7.336 -40.858 1.00 12.13 ? 448 THR A CG2 1 ATOM 3447 N N . PHE A 1 449 ? 42.755 -7.450 -37.621 1.00 9.83 ? 449 PHE A N 1 ATOM 3448 C CA . PHE A 1 449 ? 43.484 -6.353 -36.986 1.00 8.99 ? 449 PHE A CA 1 ATOM 3449 C C . PHE A 1 449 ? 44.964 -6.717 -36.884 1.00 9.62 ? 449 PHE A C 1 ATOM 3450 O O . PHE A 1 449 ? 45.836 -5.912 -37.207 1.00 9.57 ? 449 PHE A O 1 ATOM 3451 C CB . PHE A 1 449 ? 42.948 -6.084 -35.576 1.00 9.33 ? 449 PHE A CB 1 ATOM 3452 C CG . PHE A 1 449 ? 43.811 -5.148 -34.774 1.00 9.29 ? 449 PHE A CG 1 ATOM 3453 C CD1 . PHE A 1 449 ? 43.624 -3.770 -34.848 1.00 10.29 ? 449 PHE A CD1 1 ATOM 3454 C CD2 . PHE A 1 449 ? 44.851 -5.643 -33.986 1.00 8.97 ? 449 PHE A CD2 1 ATOM 3455 C CE1 . PHE A 1 449 ? 44.462 -2.897 -34.150 1.00 10.52 ? 449 PHE A CE1 1 ATOM 3456 C CE2 . PHE A 1 449 ? 45.696 -4.782 -33.286 1.00 7.81 ? 449 PHE A CE2 1 ATOM 3457 C CZ . PHE A 1 449 ? 45.503 -3.405 -33.367 1.00 9.29 ? 449 PHE A CZ 1 ATOM 3458 N N . CYS A 1 450 ? 45.240 -7.933 -36.421 1.00 7.86 ? 450 CYS A N 1 ATOM 3459 C CA . CYS A 1 450 ? 46.611 -8.396 -36.268 1.00 8.53 ? 450 CYS A CA 1 ATOM 3460 C C . CYS A 1 450 ? 47.390 -8.368 -37.572 1.00 9.19 ? 450 CYS A C 1 ATOM 3461 O O . CYS A 1 450 ? 48.511 -7.865 -37.621 1.00 10.50 ? 450 CYS A O 1 ATOM 3462 C CB . CYS A 1 450 ? 46.625 -9.813 -35.692 1.00 9.56 ? 450 CYS A CB 1 ATOM 3463 S SG . CYS A 1 450 ? 46.328 -9.844 -33.897 1.00 11.00 ? 450 CYS A SG 1 ATOM 3464 N N . ARG A 1 451 ? 46.790 -8.902 -38.630 1.00 7.64 ? 451 ARG A N 1 ATOM 3465 C CA . ARG A 1 451 ? 47.450 -8.949 -39.927 1.00 9.18 ? 451 ARG A CA 1 ATOM 3466 C C . ARG A 1 451 ? 47.694 -7.590 -40.575 1.00 9.38 ? 451 ARG A C 1 ATOM 3467 O O . ARG A 1 451 ? 48.788 -7.319 -41.061 1.00 10.35 ? 451 ARG A O 1 ATOM 3468 C CB . ARG A 1 451 ? 46.640 -9.810 -40.901 1.00 8.18 ? 451 ARG A CB 1 ATOM 3469 C CG . ARG A 1 451 ? 46.673 -11.308 -40.619 1.00 8.79 ? 451 ARG A CG 1 ATOM 3470 C CD . ARG A 1 451 ? 45.860 -12.055 -41.677 1.00 8.12 ? 451 ARG A CD 1 ATOM 3471 N NE . ARG A 1 451 ? 45.820 -13.502 -41.476 1.00 8.86 ? 451 ARG A NE 1 ATOM 3472 C CZ . ARG A 1 451 ? 46.821 -14.334 -41.754 1.00 8.26 ? 451 ARG A CZ 1 ATOM 3473 N NH1 . ARG A 1 451 ? 47.965 -13.872 -42.247 1.00 11.10 ? 451 ARG A NH1 1 ATOM 3474 N NH2 . ARG A 1 451 ? 46.665 -15.638 -41.561 1.00 10.22 ? 451 ARG A NH2 1 ATOM 3475 N N . GLU A 1 452 ? 46.672 -6.740 -40.585 1.00 10.20 ? 452 GLU A N 1 ATOM 3476 C CA . GLU A 1 452 ? 46.780 -5.437 -41.229 1.00 11.00 ? 452 GLU A CA 1 ATOM 3477 C C . GLU A 1 452 ? 47.499 -4.333 -40.469 1.00 10.68 ? 452 GLU A C 1 ATOM 3478 O O . GLU A 1 452 ? 47.920 -3.350 -41.073 1.00 12.95 ? 452 GLU A O 1 ATOM 3479 C CB . GLU A 1 452 ? 45.389 -4.928 -41.616 1.00 12.88 ? 452 GLU A CB 1 ATOM 3480 C CG . GLU A 1 452 ? 44.599 -5.886 -42.488 1.00 19.70 ? 452 GLU A CG 1 ATOM 3481 C CD . GLU A 1 452 ? 43.417 -5.216 -43.158 1.00 22.06 ? 452 GLU A CD 1 ATOM 3482 O OE1 . GLU A 1 452 ? 42.653 -4.519 -42.459 1.00 20.99 ? 452 GLU A OE1 1 ATOM 3483 O OE2 . GLU A 1 452 ? 43.253 -5.390 -44.385 1.00 24.79 ? 452 GLU A OE2 1 ATOM 3484 N N . SER A 1 453 ? 47.655 -4.486 -39.159 1.00 8.89 ? 453 SER A N 1 ATOM 3485 C CA . SER A 1 453 ? 48.302 -3.442 -38.369 1.00 8.59 ? 453 SER A CA 1 ATOM 3486 C C . SER A 1 453 ? 49.692 -3.806 -37.860 1.00 8.64 ? 453 SER A C 1 ATOM 3487 O O . SER A 1 453 ? 50.340 -2.996 -37.200 1.00 9.23 ? 453 SER A O 1 ATOM 3488 C CB . SER A 1 453 ? 47.420 -3.080 -37.170 1.00 7.47 ? 453 SER A CB 1 ATOM 3489 O OG . SER A 1 453 ? 47.432 -4.121 -36.203 1.00 9.13 ? 453 SER A OG 1 ATOM 3490 N N . VAL A 1 454 ? 50.150 -5.013 -38.179 1.00 8.40 ? 454 VAL A N 1 ATOM 3491 C CA . VAL A 1 454 ? 51.447 -5.496 -37.710 1.00 8.04 ? 454 VAL A CA 1 ATOM 3492 C C . VAL A 1 454 ? 52.656 -4.621 -38.037 1.00 8.88 ? 454 VAL A C 1 ATOM 3493 O O . VAL A 1 454 ? 52.705 -3.958 -39.073 1.00 8.48 ? 454 VAL A O 1 ATOM 3494 C CB . VAL A 1 454 ? 51.725 -6.932 -38.238 1.00 8.15 ? 454 VAL A CB 1 ATOM 3495 C CG1 . VAL A 1 454 ? 52.094 -6.896 -39.719 1.00 8.28 ? 454 VAL A CG1 1 ATOM 3496 C CG2 . VAL A 1 454 ? 52.832 -7.587 -37.411 1.00 10.05 ? 454 VAL A CG2 1 ATOM 3497 N N . ALA A 1 455 ? 53.626 -4.633 -37.125 1.00 7.29 ? 455 ALA A N 1 ATOM 3498 C CA . ALA A 1 455 ? 54.877 -3.893 -37.271 1.00 7.27 ? 455 ALA A CA 1 ATOM 3499 C C . ALA A 1 455 ? 55.966 -4.780 -36.679 1.00 7.25 ? 455 ALA A C 1 ATOM 3500 O O . ALA A 1 455 ? 55.675 -5.869 -36.196 1.00 7.07 ? 455 ALA A O 1 ATOM 3501 C CB . ALA A 1 455 ? 54.806 -2.577 -36.510 1.00 8.53 ? 455 ALA A CB 1 ATOM 3502 N N . SER A 1 456 ? 57.218 -4.332 -36.724 1.00 6.57 ? 456 SER A N 1 ATOM 3503 C CA . SER A 1 456 ? 58.304 -5.118 -36.145 1.00 6.93 ? 456 SER A CA 1 ATOM 3504 C C . SER A 1 456 ? 58.586 -4.668 -34.717 1.00 8.78 ? 456 SER A C 1 ATOM 3505 O O . SER A 1 456 ? 58.469 -3.483 -34.399 1.00 9.52 ? 456 SER A O 1 ATOM 3506 C CB . SER A 1 456 ? 59.586 -4.968 -36.967 1.00 7.60 ? 456 SER A CB 1 ATOM 3507 O OG . SER A 1 456 ? 60.674 -5.613 -36.316 1.00 6.82 ? 456 SER A OG 1 ATOM 3508 N N . TYR A 1 457 ? 58.944 -5.614 -33.854 1.00 8.70 ? 457 TYR A N 1 ATOM 3509 C CA . TYR A 1 457 ? 59.280 -5.274 -32.476 1.00 10.13 ? 457 TYR A CA 1 ATOM 3510 C C . TYR A 1 457 ? 60.784 -4.987 -32.438 1.00 10.59 ? 457 TYR A C 1 ATOM 3511 O O . TYR A 1 457 ? 61.340 -4.662 -31.389 1.00 10.42 ? 457 TYR A O 1 ATOM 3512 C CB . TYR A 1 457 ? 58.944 -6.427 -31.516 1.00 10.70 ? 457 TYR A CB 1 ATOM 3513 C CG . TYR A 1 457 ? 58.480 -5.936 -30.160 1.00 12.82 ? 457 TYR A CG 1 ATOM 3514 C CD1 . TYR A 1 457 ? 57.121 -5.797 -29.875 1.00 11.93 ? 457 TYR A CD1 1 ATOM 3515 C CD2 . TYR A 1 457 ? 59.399 -5.526 -29.194 1.00 14.35 ? 457 TYR A CD2 1 ATOM 3516 C CE1 . TYR A 1 457 ? 56.688 -5.254 -28.665 1.00 15.06 ? 457 TYR A CE1 1 ATOM 3517 C CE2 . TYR A 1 457 ? 58.979 -4.983 -27.984 1.00 16.86 ? 457 TYR A CE2 1 ATOM 3518 C CZ . TYR A 1 457 ? 57.624 -4.847 -27.727 1.00 16.86 ? 457 TYR A CZ 1 ATOM 3519 O OH . TYR A 1 457 ? 57.208 -4.284 -26.543 1.00 20.98 ? 457 TYR A OH 1 ATOM 3520 N N . TRP A 1 458 ? 61.424 -5.115 -33.601 1.00 9.49 ? 458 TRP A N 1 ATOM 3521 C CA . TRP A 1 458 ? 62.857 -4.869 -33.776 1.00 9.48 ? 458 TRP A CA 1 ATOM 3522 C C . TRP A 1 458 ? 63.742 -5.903 -33.092 1.00 8.14 ? 458 TRP A C 1 ATOM 3523 O O . TRP A 1 458 ? 64.948 -5.695 -32.942 1.00 8.06 ? 458 TRP A O 1 ATOM 3524 C CB . TRP A 1 458 ? 63.242 -3.486 -33.245 1.00 10.95 ? 458 TRP A CB 1 ATOM 3525 C CG . TRP A 1 458 ? 62.349 -2.367 -33.681 1.00 13.43 ? 458 TRP A CG 1 ATOM 3526 C CD1 . TRP A 1 458 ? 62.028 -2.017 -34.961 1.00 13.25 ? 458 TRP A CD1 1 ATOM 3527 C CD2 . TRP A 1 458 ? 61.684 -1.429 -32.828 1.00 14.90 ? 458 TRP A CD2 1 ATOM 3528 N NE1 . TRP A 1 458 ? 61.206 -0.914 -34.956 1.00 14.85 ? 458 TRP A NE1 1 ATOM 3529 C CE2 . TRP A 1 458 ? 60.980 -0.533 -33.660 1.00 15.81 ? 458 TRP A CE2 1 ATOM 3530 C CE3 . TRP A 1 458 ? 61.615 -1.257 -31.438 1.00 15.16 ? 458 TRP A CE3 1 ATOM 3531 C CZ2 . TRP A 1 458 ? 60.215 0.523 -33.148 1.00 17.02 ? 458 TRP A CZ2 1 ATOM 3532 C CZ3 . TRP A 1 458 ? 60.856 -0.209 -30.929 1.00 16.76 ? 458 TRP A CZ3 1 ATOM 3533 C CH2 . TRP A 1 458 ? 60.167 0.667 -31.784 1.00 17.94 ? 458 TRP A CH2 1 ATOM 3534 N N . HIS A 1 459 ? 63.153 -7.019 -32.679 1.00 7.50 ? 459 HIS A N 1 ATOM 3535 C CA . HIS A 1 459 ? 63.923 -8.053 -32.004 1.00 7.34 ? 459 HIS A CA 1 ATOM 3536 C C . HIS A 1 459 ? 64.218 -9.249 -32.901 1.00 8.72 ? 459 HIS A C 1 ATOM 3537 O O . HIS A 1 459 ? 64.317 -10.383 -32.423 1.00 9.09 ? 459 HIS A O 1 ATOM 3538 C CB . HIS A 1 459 ? 63.183 -8.511 -30.741 1.00 6.64 ? 459 HIS A CB 1 ATOM 3539 C CG . HIS A 1 459 ? 63.008 -7.432 -29.720 1.00 7.38 ? 459 HIS A CG 1 ATOM 3540 N ND1 . HIS A 1 459 ? 62.338 -7.633 -28.529 1.00 9.30 ? 459 HIS A ND1 1 ATOM 3541 C CD2 . HIS A 1 459 ? 63.420 -6.142 -29.701 1.00 8.61 ? 459 HIS A CD2 1 ATOM 3542 C CE1 . HIS A 1 459 ? 62.345 -6.516 -27.827 1.00 9.03 ? 459 HIS A CE1 1 ATOM 3543 N NE2 . HIS A 1 459 ? 62.996 -5.593 -28.515 1.00 8.24 ? 459 HIS A NE2 1 ATOM 3544 N N . TYR A 1 460 ? 64.357 -8.997 -34.200 1.00 6.24 ? 460 TYR A N 1 ATOM 3545 C CA . TYR A 1 460 ? 64.653 -10.066 -35.151 1.00 7.59 ? 460 TYR A CA 1 ATOM 3546 C C . TYR A 1 460 ? 65.934 -10.787 -34.754 1.00 7.79 ? 460 TYR A C 1 ATOM 3547 O O . TYR A 1 460 ? 66.840 -10.203 -34.155 1.00 8.04 ? 460 TYR A O 1 ATOM 3548 C CB . TYR A 1 460 ? 64.764 -9.496 -36.569 1.00 6.20 ? 460 TYR A CB 1 ATOM 3549 C CG . TYR A 1 460 ? 65.557 -8.213 -36.634 1.00 4.98 ? 460 TYR A CG 1 ATOM 3550 C CD1 . TYR A 1 460 ? 66.951 -8.232 -36.646 1.00 7.53 ? 460 TYR A CD1 1 ATOM 3551 C CD2 . TYR A 1 460 ? 64.912 -6.973 -36.620 1.00 6.16 ? 460 TYR A CD2 1 ATOM 3552 C CE1 . TYR A 1 460 ? 67.689 -7.046 -36.636 1.00 7.67 ? 460 TYR A CE1 1 ATOM 3553 C CE2 . TYR A 1 460 ? 65.640 -5.782 -36.609 1.00 5.93 ? 460 TYR A CE2 1 ATOM 3554 C CZ . TYR A 1 460 ? 67.029 -5.829 -36.614 1.00 8.99 ? 460 TYR A CZ 1 ATOM 3555 O OH . TYR A 1 460 ? 67.762 -4.663 -36.553 1.00 9.51 ? 460 TYR A OH 1 ATOM 3556 N N . HIS A 1 461 ? 65.997 -12.067 -35.098 1.00 6.94 ? 461 HIS A N 1 ATOM 3557 C CA . HIS A 1 461 ? 67.126 -12.912 -34.748 1.00 7.43 ? 461 HIS A CA 1 ATOM 3558 C C . HIS A 1 461 ? 67.156 -14.108 -35.691 1.00 7.73 ? 461 HIS A C 1 ATOM 3559 O O . HIS A 1 461 ? 66.268 -14.267 -36.529 1.00 7.73 ? 461 HIS A O 1 ATOM 3560 C CB . HIS A 1 461 ? 66.952 -13.409 -33.311 1.00 7.42 ? 461 HIS A CB 1 ATOM 3561 C CG . HIS A 1 461 ? 65.604 -14.008 -33.048 1.00 6.43 ? 461 HIS A CG 1 ATOM 3562 N ND1 . HIS A 1 461 ? 64.478 -13.242 -32.821 1.00 7.03 ? 461 HIS A ND1 1 ATOM 3563 C CD2 . HIS A 1 461 ? 65.188 -15.296 -33.037 1.00 7.99 ? 461 HIS A CD2 1 ATOM 3564 C CE1 . HIS A 1 461 ? 63.429 -14.033 -32.684 1.00 6.95 ? 461 HIS A CE1 1 ATOM 3565 N NE2 . HIS A 1 461 ? 63.833 -15.286 -32.811 1.00 7.39 ? 461 HIS A NE2 1 ATOM 3566 N N . GLY A 1 462 ? 68.174 -14.949 -35.541 1.00 7.65 ? 462 GLY A N 1 ATOM 3567 C CA . GLY A 1 462 ? 68.296 -16.126 -36.385 1.00 7.87 ? 462 GLY A CA 1 ATOM 3568 C C . GLY A 1 462 ? 69.133 -15.879 -37.624 1.00 7.71 ? 462 GLY A C 1 ATOM 3569 O O . GLY A 1 462 ? 69.755 -14.827 -37.756 1.00 8.95 ? 462 GLY A O 1 ATOM 3570 N N . GLY A 1 463 ? 69.157 -16.855 -38.530 1.00 8.68 ? 463 GLY A N 1 ATOM 3571 C CA . GLY A 1 463 ? 69.924 -16.718 -39.759 1.00 7.37 ? 463 GLY A CA 1 ATOM 3572 C C . GLY A 1 463 ? 71.235 -17.488 -39.806 1.00 8.15 ? 463 GLY A C 1 ATOM 3573 O O . GLY A 1 463 ? 71.824 -17.656 -40.876 1.00 9.96 ? 463 GLY A O 1 ATOM 3574 N N . CYS A 1 464 ? 71.701 -17.947 -38.649 1.00 7.43 ? 464 CYS A N 1 ATOM 3575 C CA . CYS A 1 464 ? 72.949 -18.707 -38.551 1.00 7.16 ? 464 CYS A CA 1 ATOM 3576 C C . CYS A 1 464 ? 72.807 -19.555 -37.289 1.00 8.12 ? 464 CYS A C 1 ATOM 3577 O O . CYS A 1 464 ? 73.601 -19.458 -36.350 1.00 6.63 ? 464 CYS A O 1 ATOM 3578 C CB . CYS A 1 464 ? 74.127 -17.743 -38.420 1.00 9.76 ? 464 CYS A CB 1 ATOM 3579 S SG . CYS A 1 464 ? 75.734 -18.513 -38.644 1.00 10.91 ? 464 CYS A SG 1 ATOM 3580 N N . LEU A 1 465 ? 71.786 -20.404 -37.296 1.00 7.61 ? 465 LEU A N 1 ATOM 3581 C CA . LEU A 1 465 ? 71.436 -21.224 -36.142 1.00 9.46 ? 465 LEU A CA 1 ATOM 3582 C C . LEU A 1 465 ? 72.371 -22.311 -35.636 1.00 9.63 ? 465 LEU A C 1 ATOM 3583 O O . LEU A 1 465 ? 73.051 -22.995 -36.401 1.00 9.62 ? 465 LEU A O 1 ATOM 3584 C CB . LEU A 1 465 ? 70.063 -21.873 -36.369 1.00 9.53 ? 465 LEU A CB 1 ATOM 3585 C CG . LEU A 1 465 ? 68.865 -20.992 -36.728 1.00 11.30 ? 465 LEU A CG 1 ATOM 3586 C CD1 . LEU A 1 465 ? 67.615 -21.861 -36.755 1.00 10.16 ? 465 LEU A CD1 1 ATOM 3587 C CD2 . LEU A 1 465 ? 68.706 -19.873 -35.717 1.00 11.05 ? 465 LEU A CD2 1 ATOM 3588 N N . VAL A 1 466 ? 72.386 -22.451 -34.315 1.00 9.97 ? 466 VAL A N 1 ATOM 3589 C CA . VAL A 1 466 ? 73.145 -23.503 -33.663 1.00 9.36 ? 466 VAL A CA 1 ATOM 3590 C C . VAL A 1 466 ? 72.364 -24.750 -34.067 1.00 10.70 ? 466 VAL A C 1 ATOM 3591 O O . VAL A 1 466 ? 71.136 -24.777 -33.960 1.00 11.58 ? 466 VAL A O 1 ATOM 3592 C CB . VAL A 1 466 ? 73.098 -23.361 -32.128 1.00 10.26 ? 466 VAL A CB 1 ATOM 3593 C CG1 . VAL A 1 466 ? 73.508 -24.673 -31.468 1.00 10.26 ? 466 VAL A CG1 1 ATOM 3594 C CG2 . VAL A 1 466 ? 74.016 -22.235 -31.686 1.00 10.07 ? 466 VAL A CG2 1 ATOM 3595 N N . GLY A 1 467 ? 73.067 -25.770 -34.545 1.00 10.45 ? 467 GLY A N 1 ATOM 3596 C CA . GLY A 1 467 ? 72.397 -26.987 -34.966 1.00 10.75 ? 467 GLY A CA 1 ATOM 3597 C C . GLY A 1 467 ? 72.115 -27.018 -36.458 1.00 11.81 ? 467 GLY A C 1 ATOM 3598 O O . GLY A 1 467 ? 71.709 -28.048 -36.994 1.00 12.25 ? 467 GLY A O 1 ATOM 3599 N N . LYS A 1 468 ? 72.318 -25.884 -37.127 1.00 11.99 ? 468 LYS A N 1 ATOM 3600 C CA . LYS A 1 468 ? 72.096 -25.785 -38.569 1.00 11.84 ? 468 LYS A CA 1 ATOM 3601 C C . LYS A 1 468 ? 73.385 -25.337 -39.249 1.00 12.04 ? 468 LYS A C 1 ATOM 3602 O O . LYS A 1 468 ? 73.837 -25.956 -40.214 1.00 13.85 ? 468 LYS A O 1 ATOM 3603 C CB . LYS A 1 468 ? 70.975 -24.785 -38.879 1.00 12.92 ? 468 LYS A CB 1 ATOM 3604 C CG . LYS A 1 468 ? 69.616 -25.163 -38.308 1.00 14.22 ? 468 LYS A CG 1 ATOM 3605 C CD . LYS A 1 468 ? 69.075 -26.435 -38.945 1.00 18.21 ? 468 LYS A CD 1 ATOM 3606 C CE . LYS A 1 468 ? 67.718 -26.803 -38.360 1.00 21.01 ? 468 LYS A CE 1 ATOM 3607 N NZ . LYS A 1 468 ? 67.132 -27.995 -39.032 1.00 25.68 ? 468 LYS A NZ 1 ATOM 3608 N N . VAL A 1 469 ? 73.971 -24.252 -38.747 1.00 10.22 ? 469 VAL A N 1 ATOM 3609 C CA . VAL A 1 469 ? 75.220 -23.736 -39.296 1.00 9.20 ? 469 VAL A CA 1 ATOM 3610 C C . VAL A 1 469 ? 76.339 -23.877 -38.265 1.00 8.05 ? 469 VAL A C 1 ATOM 3611 O O . VAL A 1 469 ? 77.480 -24.177 -38.610 1.00 9.90 ? 469 VAL A O 1 ATOM 3612 C CB . VAL A 1 469 ? 75.101 -22.232 -39.673 1.00 6.39 ? 469 VAL A CB 1 ATOM 3613 C CG1 . VAL A 1 469 ? 76.413 -21.743 -40.270 1.00 8.77 ? 469 VAL A CG1 1 ATOM 3614 C CG2 . VAL A 1 469 ? 73.961 -22.023 -40.661 1.00 8.53 ? 469 VAL A CG2 1 ATOM 3615 N N . LEU A 1 470 ? 75.999 -23.663 -36.999 1.00 8.42 ? 470 LEU A N 1 ATOM 3616 C CA . LEU A 1 470 ? 76.973 -23.730 -35.909 1.00 7.84 ? 470 LEU A CA 1 ATOM 3617 C C . LEU A 1 470 ? 76.806 -24.956 -35.021 1.00 9.32 ? 470 LEU A C 1 ATOM 3618 O O . LEU A 1 470 ? 75.743 -25.578 -34.995 1.00 9.80 ? 470 LEU A O 1 ATOM 3619 C CB . LEU A 1 470 ? 76.834 -22.495 -35.015 1.00 8.80 ? 470 LEU A CB 1 ATOM 3620 C CG . LEU A 1 470 ? 76.740 -21.121 -35.674 1.00 8.12 ? 470 LEU A CG 1 ATOM 3621 C CD1 . LEU A 1 470 ? 76.505 -20.066 -34.593 1.00 8.40 ? 470 LEU A CD1 1 ATOM 3622 C CD2 . LEU A 1 470 ? 78.006 -20.830 -36.452 1.00 7.36 ? 470 LEU A CD2 1 ATOM 3623 N N . ASP A 1 471 ? 77.859 -25.295 -34.283 1.00 10.66 ? 471 ASP A N 1 ATOM 3624 C CA . ASP A 1 471 ? 77.776 -26.412 -33.353 1.00 11.03 ? 471 ASP A CA 1 ATOM 3625 C C . ASP A 1 471 ? 77.540 -25.840 -31.954 1.00 11.49 ? 471 ASP A C 1 ATOM 3626 O O . ASP A 1 471 ? 77.341 -24.629 -31.806 1.00 10.86 ? 471 ASP A O 1 ATOM 3627 C CB . ASP A 1 471 ? 79.043 -27.291 -33.413 1.00 12.47 ? 471 ASP A CB 1 ATOM 3628 C CG . ASP A 1 471 ? 80.297 -26.592 -32.912 1.00 12.53 ? 471 ASP A CG 1 ATOM 3629 O OD1 . ASP A 1 471 ? 81.386 -27.185 -33.083 1.00 15.54 ? 471 ASP A OD1 1 ATOM 3630 O OD2 . ASP A 1 471 ? 80.220 -25.479 -32.349 1.00 12.26 ? 471 ASP A OD2 1 ATOM 3631 N N . GLY A 1 472 ? 77.557 -26.697 -30.938 1.00 9.75 ? 472 GLY A N 1 ATOM 3632 C CA . GLY A 1 472 ? 77.305 -26.255 -29.574 1.00 10.70 ? 472 GLY A CA 1 ATOM 3633 C C . GLY A 1 472 ? 78.300 -25.289 -28.961 1.00 10.15 ? 472 GLY A C 1 ATOM 3634 O O . GLY A 1 472 ? 78.045 -24.732 -27.886 1.00 11.06 ? 472 GLY A O 1 ATOM 3635 N N . ASP A 1 473 ? 79.430 -25.094 -29.631 1.00 10.91 ? 473 ASP A N 1 ATOM 3636 C CA . ASP A 1 473 ? 80.467 -24.186 -29.152 1.00 11.70 ? 473 ASP A CA 1 ATOM 3637 C C . ASP A 1 473 ? 80.508 -22.933 -30.027 1.00 10.94 ? 473 ASP A C 1 ATOM 3638 O O . ASP A 1 473 ? 81.451 -22.150 -29.962 1.00 10.21 ? 473 ASP A O 1 ATOM 3639 C CB . ASP A 1 473 ? 81.830 -24.884 -29.177 1.00 13.67 ? 473 ASP A CB 1 ATOM 3640 C CG . ASP A 1 473 ? 81.866 -26.125 -28.299 1.00 16.92 ? 473 ASP A CG 1 ATOM 3641 O OD1 . ASP A 1 473 ? 81.599 -26.002 -27.087 1.00 19.77 ? 473 ASP A OD1 1 ATOM 3642 O OD2 . ASP A 1 473 ? 82.160 -27.223 -28.818 1.00 20.36 ? 473 ASP A OD2 1 ATOM 3643 N N . PHE A 1 474 ? 79.469 -22.770 -30.841 1.00 10.02 ? 474 PHE A N 1 ATOM 3644 C CA . PHE A 1 474 ? 79.314 -21.640 -31.755 1.00 9.44 ? 474 PHE A CA 1 ATOM 3645 C C . PHE A 1 474 ? 80.309 -21.598 -32.906 1.00 9.23 ? 474 PHE A C 1 ATOM 3646 O O . PHE A 1 474 ? 80.514 -20.554 -33.532 1.00 9.69 ? 474 PHE A O 1 ATOM 3647 C CB . PHE A 1 474 ? 79.333 -20.316 -30.983 1.00 8.20 ? 474 PHE A CB 1 ATOM 3648 C CG . PHE A 1 474 ? 78.224 -20.197 -29.974 1.00 8.20 ? 474 PHE A CG 1 ATOM 3649 C CD1 . PHE A 1 474 ? 78.361 -20.747 -28.703 1.00 7.63 ? 474 PHE A CD1 1 ATOM 3650 C CD2 . PHE A 1 474 ? 77.025 -19.579 -30.314 1.00 9.29 ? 474 PHE A CD2 1 ATOM 3651 C CE1 . PHE A 1 474 ? 77.317 -20.686 -27.780 1.00 8.75 ? 474 PHE A CE1 1 ATOM 3652 C CE2 . PHE A 1 474 ? 75.975 -19.513 -29.402 1.00 9.20 ? 474 PHE A CE2 1 ATOM 3653 C CZ . PHE A 1 474 ? 76.121 -20.068 -28.133 1.00 10.67 ? 474 PHE A CZ 1 ATOM 3654 N N . ARG A 1 475 ? 80.926 -22.738 -33.192 1.00 7.95 ? 475 ARG A N 1 ATOM 3655 C CA . ARG A 1 475 ? 81.863 -22.822 -34.301 1.00 8.07 ? 475 ARG A CA 1 ATOM 3656 C C . ARG A 1 475 ? 81.069 -23.080 -35.577 1.00 8.07 ? 475 ARG A C 1 ATOM 3657 O O . ARG A 1 475 ? 80.059 -23.786 -35.552 1.00 8.73 ? 475 ARG A O 1 ATOM 3658 C CB . ARG A 1 475 ? 82.833 -23.996 -34.121 1.00 8.33 ? 475 ARG A CB 1 ATOM 3659 C CG . ARG A 1 475 ? 83.789 -23.920 -32.949 1.00 9.89 ? 475 ARG A CG 1 ATOM 3660 C CD . ARG A 1 475 ? 84.856 -24.994 -33.129 1.00 12.61 ? 475 ARG A CD 1 ATOM 3661 N NE . ARG A 1 475 ? 85.777 -25.110 -32.003 1.00 13.22 ? 475 ARG A NE 1 ATOM 3662 C CZ A ARG A 1 475 ? 85.429 -25.542 -30.797 0.50 14.38 ? 475 ARG A CZ 1 ATOM 3663 C CZ B ARG A 1 475 ? 87.018 -24.640 -32.004 0.50 15.02 ? 475 ARG A CZ 1 ATOM 3664 N NH1 A ARG A 1 475 ? 84.178 -25.897 -30.554 0.50 17.31 ? 475 ARG A NH1 1 ATOM 3665 N NH1 B ARG A 1 475 ? 87.494 -24.024 -33.074 0.50 17.94 ? 475 ARG A NH1 1 ATOM 3666 N NH2 A ARG A 1 475 ? 86.334 -25.631 -29.837 0.50 17.22 ? 475 ARG A NH2 1 ATOM 3667 N NH2 B ARG A 1 475 ? 87.780 -24.775 -30.932 0.50 17.71 ? 475 ARG A NH2 1 ATOM 3668 N N . VAL A 1 476 ? 81.516 -22.502 -36.687 1.00 8.63 ? 476 VAL A N 1 ATOM 3669 C CA . VAL A 1 476 ? 80.867 -22.748 -37.969 1.00 8.04 ? 476 VAL A CA 1 ATOM 3670 C C . VAL A 1 476 ? 81.350 -24.152 -38.347 1.00 8.98 ? 476 VAL A C 1 ATOM 3671 O O . VAL A 1 476 ? 82.549 -24.381 -38.503 1.00 9.75 ? 476 VAL A O 1 ATOM 3672 C CB . VAL A 1 476 ? 81.321 -21.732 -39.040 1.00 8.70 ? 476 VAL A CB 1 ATOM 3673 C CG1 . VAL A 1 476 ? 80.835 -22.164 -40.415 1.00 9.48 ? 476 VAL A CG1 1 ATOM 3674 C CG2 . VAL A 1 476 ? 80.765 -20.350 -38.706 1.00 10.83 ? 476 VAL A CG2 1 ATOM 3675 N N . THR A 1 477 ? 80.425 -25.095 -38.482 1.00 9.77 ? 477 THR A N 1 ATOM 3676 C CA . THR A 1 477 ? 80.817 -26.463 -38.801 1.00 10.61 ? 477 THR A CA 1 ATOM 3677 C C . THR A 1 477 ? 81.609 -26.581 -40.100 1.00 11.02 ? 477 THR A C 1 ATOM 3678 O O . THR A 1 477 ? 81.317 -25.907 -41.090 1.00 10.93 ? 477 THR A O 1 ATOM 3679 C CB . THR A 1 477 ? 79.587 -27.402 -38.868 1.00 10.80 ? 477 THR A CB 1 ATOM 3680 O OG1 . THR A 1 477 ? 78.739 -27.019 -39.959 1.00 13.17 ? 477 THR A OG1 1 ATOM 3681 C CG2 . THR A 1 477 ? 78.796 -27.332 -37.565 1.00 10.12 ? 477 THR A CG2 1 ATOM 3682 N N . GLY A 1 478 ? 82.634 -27.430 -40.077 1.00 10.40 ? 478 GLY A N 1 ATOM 3683 C CA . GLY A 1 478 ? 83.445 -27.648 -41.260 1.00 10.93 ? 478 GLY A CA 1 ATOM 3684 C C . GLY A 1 478 ? 84.557 -26.649 -41.500 1.00 11.41 ? 478 GLY A C 1 ATOM 3685 O O . GLY A 1 478 ? 85.357 -26.828 -42.416 1.00 12.08 ? 478 GLY A O 1 ATOM 3686 N N . ILE A 1 479 ? 84.615 -25.603 -40.682 1.00 10.50 ? 479 ILE A N 1 ATOM 3687 C CA . ILE A 1 479 ? 85.643 -24.576 -40.823 1.00 10.75 ? 479 ILE A CA 1 ATOM 3688 C C . ILE A 1 479 ? 86.329 -24.330 -39.483 1.00 10.79 ? 479 ILE A C 1 ATOM 3689 O O . ILE A 1 479 ? 85.662 -24.133 -38.471 1.00 11.45 ? 479 ILE A O 1 ATOM 3690 C CB . ILE A 1 479 ? 85.034 -23.240 -41.312 1.00 9.93 ? 479 ILE A CB 1 ATOM 3691 C CG1 . ILE A 1 479 ? 84.300 -23.457 -42.636 1.00 10.72 ? 479 ILE A CG1 1 ATOM 3692 C CG2 . ILE A 1 479 ? 86.130 -22.197 -41.479 1.00 9.17 ? 479 ILE A CG2 1 ATOM 3693 C CD1 . ILE A 1 479 ? 83.641 -22.209 -43.177 1.00 11.84 ? 479 ILE A CD1 1 ATOM 3694 N N . ASN A 1 480 ? 87.659 -24.351 -39.476 1.00 11.26 ? 480 ASN A N 1 ATOM 3695 C CA . ASN A 1 480 ? 88.410 -24.116 -38.246 1.00 11.06 ? 480 ASN A CA 1 ATOM 3696 C C . ASN A 1 480 ? 88.635 -22.625 -38.025 1.00 10.70 ? 480 ASN A C 1 ATOM 3697 O O . ASN A 1 480 ? 88.616 -21.838 -38.974 1.00 9.54 ? 480 ASN A O 1 ATOM 3698 C CB . ASN A 1 480 ? 89.773 -24.815 -38.292 1.00 12.88 ? 480 ASN A CB 1 ATOM 3699 C CG . ASN A 1 480 ? 89.655 -26.313 -38.483 1.00 13.91 ? 480 ASN A CG 1 ATOM 3700 O OD1 . ASN A 1 480 ? 88.818 -26.962 -37.863 1.00 15.27 ? 480 ASN A OD1 1 ATOM 3701 N ND2 . ASN A 1 480 ? 90.506 -26.872 -39.339 1.00 17.19 ? 480 ASN A ND2 1 ATOM 3702 N N . ALA A 1 481 ? 88.836 -22.256 -36.761 1.00 9.82 ? 481 ALA A N 1 ATOM 3703 C CA . ALA A 1 481 ? 89.105 -20.874 -36.363 1.00 8.57 ? 481 ALA A CA 1 ATOM 3704 C C . ALA A 1 481 ? 88.042 -19.858 -36.770 1.00 8.01 ? 481 ALA A C 1 ATOM 3705 O O . ALA A 1 481 ? 88.363 -18.700 -37.042 1.00 8.48 ? 481 ALA A O 1 ATOM 3706 C CB . ALA A 1 481 ? 90.463 -20.440 -36.905 1.00 11.83 ? 481 ALA A CB 1 ATOM 3707 N N . LEU A 1 482 ? 86.784 -20.285 -36.803 1.00 8.10 ? 482 LEU A N 1 ATOM 3708 C CA . LEU A 1 482 ? 85.692 -19.389 -37.171 1.00 7.58 ? 482 LEU A CA 1 ATOM 3709 C C . LEU A 1 482 ? 84.449 -19.633 -36.322 1.00 7.82 ? 482 LEU A C 1 ATOM 3710 O O . LEU A 1 482 ? 83.922 -20.743 -36.282 1.00 7.89 ? 482 LEU A O 1 ATOM 3711 C CB . LEU A 1 482 ? 85.329 -19.569 -38.649 1.00 8.71 ? 482 LEU A CB 1 ATOM 3712 C CG . LEU A 1 482 ? 84.202 -18.669 -39.169 1.00 7.65 ? 482 LEU A CG 1 ATOM 3713 C CD1 . LEU A 1 482 ? 84.651 -17.213 -39.142 1.00 9.69 ? 482 LEU A CD1 1 ATOM 3714 C CD2 . LEU A 1 482 ? 83.822 -19.081 -40.583 1.00 8.39 ? 482 LEU A CD2 1 ATOM 3715 N N . ARG A 1 483 ? 83.983 -18.596 -35.636 1.00 7.07 ? 483 ARG A N 1 ATOM 3716 C CA . ARG A 1 483 ? 82.781 -18.729 -34.820 1.00 7.98 ? 483 ARG A CA 1 ATOM 3717 C C . ARG A 1 483 ? 81.827 -17.580 -35.108 1.00 8.23 ? 483 ARG A C 1 ATOM 3718 O O . ARG A 1 483 ? 82.182 -16.621 -35.788 1.00 8.97 ? 483 ARG A O 1 ATOM 3719 C CB . ARG A 1 483 ? 83.122 -18.736 -33.326 1.00 9.42 ? 483 ARG A CB 1 ATOM 3720 C CG . ARG A 1 483 ? 84.206 -19.727 -32.944 1.00 8.97 ? 483 ARG A CG 1 ATOM 3721 C CD . ARG A 1 483 ? 84.093 -20.145 -31.485 1.00 11.14 ? 483 ARG A CD 1 ATOM 3722 N NE . ARG A 1 483 ? 85.324 -20.778 -31.021 1.00 11.52 ? 483 ARG A NE 1 ATOM 3723 C CZ . ARG A 1 483 ? 85.409 -21.589 -29.972 1.00 12.00 ? 483 ARG A CZ 1 ATOM 3724 N NH1 . ARG A 1 483 ? 84.328 -21.889 -29.263 1.00 14.03 ? 483 ARG A NH1 1 ATOM 3725 N NH2 . ARG A 1 483 ? 86.586 -22.087 -29.621 1.00 12.83 ? 483 ARG A NH2 1 ATOM 3726 N N . VAL A 1 484 ? 80.611 -17.704 -34.595 1.00 7.24 ? 484 VAL A N 1 ATOM 3727 C CA . VAL A 1 484 ? 79.592 -16.678 -34.748 1.00 7.25 ? 484 VAL A CA 1 ATOM 3728 C C . VAL A 1 484 ? 78.973 -16.477 -33.371 1.00 7.15 ? 484 VAL A C 1 ATOM 3729 O O . VAL A 1 484 ? 78.530 -17.435 -32.739 1.00 8.80 ? 484 VAL A O 1 ATOM 3730 C CB . VAL A 1 484 ? 78.484 -17.101 -35.740 1.00 5.72 ? 484 VAL A CB 1 ATOM 3731 C CG1 . VAL A 1 484 ? 77.320 -16.119 -35.662 1.00 7.79 ? 484 VAL A CG1 1 ATOM 3732 C CG2 . VAL A 1 484 ? 79.039 -17.141 -37.162 1.00 5.07 ? 484 VAL A CG2 1 ATOM 3733 N N . VAL A 1 485 ? 78.961 -15.232 -32.900 1.00 7.15 ? 485 VAL A N 1 ATOM 3734 C CA . VAL A 1 485 ? 78.397 -14.917 -31.591 1.00 7.06 ? 485 VAL A CA 1 ATOM 3735 C C . VAL A 1 485 ? 77.624 -13.598 -31.646 1.00 7.19 ? 485 VAL A C 1 ATOM 3736 O O . VAL A 1 485 ? 78.218 -12.523 -31.648 1.00 8.16 ? 485 VAL A O 1 ATOM 3737 C CB . VAL A 1 485 ? 79.509 -14.802 -30.510 1.00 7.44 ? 485 VAL A CB 1 ATOM 3738 C CG1 . VAL A 1 485 ? 78.881 -14.622 -29.129 1.00 8.97 ? 485 VAL A CG1 1 ATOM 3739 C CG2 . VAL A 1 485 ? 80.404 -16.042 -30.540 1.00 8.21 ? 485 VAL A CG2 1 ATOM 3740 N N . ASP A 1 486 ? 76.298 -13.701 -31.703 1.00 6.60 ? 486 ASP A N 1 ATOM 3741 C CA . ASP A 1 486 ? 75.399 -12.546 -31.749 1.00 7.78 ? 486 ASP A CA 1 ATOM 3742 C C . ASP A 1 486 ? 73.955 -13.047 -31.817 1.00 7.30 ? 486 ASP A C 1 ATOM 3743 O O . ASP A 1 486 ? 73.691 -14.217 -31.550 1.00 6.88 ? 486 ASP A O 1 ATOM 3744 C CB . ASP A 1 486 ? 75.705 -11.644 -32.957 1.00 7.93 ? 486 ASP A CB 1 ATOM 3745 C CG . ASP A 1 486 ? 75.652 -12.386 -34.281 1.00 6.66 ? 486 ASP A CG 1 ATOM 3746 O OD1 . ASP A 1 486 ? 74.966 -13.427 -34.356 1.00 8.61 ? 486 ASP A OD1 1 ATOM 3747 O OD2 . ASP A 1 486 ? 76.290 -11.916 -35.251 1.00 7.75 ? 486 ASP A OD2 1 ATOM 3748 N N . GLY A 1 487 ? 73.024 -12.174 -32.193 1.00 6.79 ? 487 GLY A N 1 ATOM 3749 C CA . GLY A 1 487 ? 71.627 -12.578 -32.253 1.00 7.48 ? 487 GLY A CA 1 ATOM 3750 C C . GLY A 1 487 ? 71.203 -13.528 -33.360 1.00 6.43 ? 487 GLY A C 1 ATOM 3751 O O . GLY A 1 487 ? 70.043 -13.928 -33.411 1.00 7.89 ? 487 GLY A O 1 ATOM 3752 N N . SER A 1 488 ? 72.128 -13.910 -34.234 1.00 6.78 ? 488 SER A N 1 ATOM 3753 C CA . SER A 1 488 ? 71.800 -14.798 -35.347 1.00 6.34 ? 488 SER A CA 1 ATOM 3754 C C . SER A 1 488 ? 71.792 -16.289 -35.019 1.00 7.09 ? 488 SER A C 1 ATOM 3755 O O . SER A 1 488 ? 71.386 -17.099 -35.854 1.00 7.99 ? 488 SER A O 1 ATOM 3756 C CB . SER A 1 488 ? 72.794 -14.582 -36.494 1.00 6.29 ? 488 SER A CB 1 ATOM 3757 O OG . SER A 1 488 ? 74.067 -15.125 -36.163 1.00 8.22 ? 488 SER A OG 1 ATOM 3758 N N . THR A 1 489 ? 72.196 -16.659 -33.807 1.00 8.44 ? 489 THR A N 1 ATOM 3759 C CA . THR A 1 489 ? 72.322 -18.078 -33.482 1.00 7.40 ? 489 THR A CA 1 ATOM 3760 C C . THR A 1 489 ? 71.153 -18.913 -32.961 1.00 9.24 ? 489 THR A C 1 ATOM 3761 O O . THR A 1 489 ? 71.278 -20.137 -32.872 1.00 9.86 ? 489 THR A O 1 ATOM 3762 C CB . THR A 1 489 ? 73.515 -18.295 -32.531 1.00 9.34 ? 489 THR A CB 1 ATOM 3763 O OG1 . THR A 1 489 ? 73.142 -17.943 -31.197 1.00 11.88 ? 489 THR A OG1 1 ATOM 3764 C CG2 . THR A 1 489 ? 74.694 -17.433 -32.964 1.00 7.14 ? 489 THR A CG2 1 ATOM 3765 N N . PHE A 1 490 ? 70.029 -18.290 -32.623 1.00 8.23 ? 490 PHE A N 1 ATOM 3766 C CA . PHE A 1 490 ? 68.882 -19.051 -32.128 1.00 7.01 ? 490 PHE A CA 1 ATOM 3767 C C . PHE A 1 490 ? 67.582 -18.639 -32.808 1.00 8.17 ? 490 PHE A C 1 ATOM 3768 O O . PHE A 1 490 ? 67.405 -17.483 -33.177 1.00 9.16 ? 490 PHE A O 1 ATOM 3769 C CB . PHE A 1 490 ? 68.752 -18.894 -30.615 1.00 8.40 ? 490 PHE A CB 1 ATOM 3770 C CG . PHE A 1 490 ? 69.925 -19.441 -29.849 1.00 8.56 ? 490 PHE A CG 1 ATOM 3771 C CD1 . PHE A 1 490 ? 70.815 -18.585 -29.210 1.00 7.83 ? 490 PHE A CD1 1 ATOM 3772 C CD2 . PHE A 1 490 ? 70.142 -20.815 -29.773 1.00 8.20 ? 490 PHE A CD2 1 ATOM 3773 C CE1 . PHE A 1 490 ? 71.906 -19.085 -28.502 1.00 8.51 ? 490 PHE A CE1 1 ATOM 3774 C CE2 . PHE A 1 490 ? 71.232 -21.329 -29.066 1.00 8.94 ? 490 PHE A CE2 1 ATOM 3775 C CZ . PHE A 1 490 ? 72.115 -20.464 -28.430 1.00 7.99 ? 490 PHE A CZ 1 ATOM 3776 N N . PRO A 1 491 ? 66.648 -19.588 -32.970 1.00 8.41 ? 491 PRO A N 1 ATOM 3777 C CA . PRO A 1 491 ? 65.358 -19.329 -33.618 1.00 8.45 ? 491 PRO A CA 1 ATOM 3778 C C . PRO A 1 491 ? 64.315 -18.557 -32.821 1.00 9.20 ? 491 PRO A C 1 ATOM 3779 O O . PRO A 1 491 ? 63.477 -17.864 -33.400 1.00 9.49 ? 491 PRO A O 1 ATOM 3780 C CB . PRO A 1 491 ? 64.870 -20.730 -33.968 1.00 8.20 ? 491 PRO A CB 1 ATOM 3781 C CG . PRO A 1 491 ? 65.389 -21.543 -32.819 1.00 9.70 ? 491 PRO A CG 1 ATOM 3782 C CD . PRO A 1 491 ? 66.801 -21.024 -32.665 1.00 8.64 ? 491 PRO A CD 1 ATOM 3783 N N . TYR A 1 492 ? 64.361 -18.670 -31.500 1.00 8.77 ? 492 TYR A N 1 ATOM 3784 C CA . TYR A 1 492 ? 63.371 -18.001 -30.671 1.00 9.41 ? 492 TYR A CA 1 ATOM 3785 C C . TYR A 1 492 ? 63.973 -16.938 -29.767 1.00 9.16 ? 492 TYR A C 1 ATOM 3786 O O . TYR A 1 492 ? 65.137 -17.019 -29.385 1.00 9.09 ? 492 TYR A O 1 ATOM 3787 C CB . TYR A 1 492 ? 62.613 -19.060 -29.867 1.00 11.10 ? 492 TYR A CB 1 ATOM 3788 C CG . TYR A 1 492 ? 62.009 -20.123 -30.764 1.00 12.28 ? 492 TYR A CG 1 ATOM 3789 C CD1 . TYR A 1 492 ? 62.229 -21.481 -30.526 1.00 14.41 ? 492 TYR A CD1 1 ATOM 3790 C CD2 . TYR A 1 492 ? 61.251 -19.765 -31.883 1.00 10.80 ? 492 TYR A CD2 1 ATOM 3791 C CE1 . TYR A 1 492 ? 61.710 -22.457 -31.387 1.00 14.82 ? 492 TYR A CE1 1 ATOM 3792 C CE2 . TYR A 1 492 ? 60.732 -20.729 -32.745 1.00 13.67 ? 492 TYR A CE2 1 ATOM 3793 C CZ . TYR A 1 492 ? 60.967 -22.070 -32.493 1.00 15.65 ? 492 TYR A CZ 1 ATOM 3794 O OH . TYR A 1 492 ? 60.473 -23.016 -33.362 1.00 16.89 ? 492 TYR A OH 1 ATOM 3795 N N . THR A 1 493 ? 63.178 -15.924 -29.443 1.00 8.62 ? 493 THR A N 1 ATOM 3796 C CA . THR A 1 493 ? 63.660 -14.849 -28.594 1.00 8.70 ? 493 THR A CA 1 ATOM 3797 C C . THR A 1 493 ? 63.785 -15.355 -27.152 1.00 8.86 ? 493 THR A C 1 ATOM 3798 O O . THR A 1 493 ? 62.909 -16.053 -26.643 1.00 9.53 ? 493 THR A O 1 ATOM 3799 C CB . THR A 1 493 ? 62.724 -13.609 -28.698 1.00 10.06 ? 493 THR A CB 1 ATOM 3800 O OG1 . THR A 1 493 ? 63.393 -12.462 -28.161 1.00 11.42 ? 493 THR A OG1 1 ATOM 3801 C CG2 . THR A 1 493 ? 61.422 -13.837 -27.955 1.00 10.79 ? 493 THR A CG2 1 ATOM 3802 N N . PRO A 1 494 ? 64.892 -15.009 -26.479 1.00 8.04 ? 494 PRO A N 1 ATOM 3803 C CA . PRO A 1 494 ? 65.199 -15.406 -25.099 1.00 9.42 ? 494 PRO A CA 1 ATOM 3804 C C . PRO A 1 494 ? 64.336 -14.795 -23.999 1.00 8.36 ? 494 PRO A C 1 ATOM 3805 O O . PRO A 1 494 ? 64.247 -15.340 -22.899 1.00 9.94 ? 494 PRO A O 1 ATOM 3806 C CB . PRO A 1 494 ? 66.667 -15.021 -24.957 1.00 9.99 ? 494 PRO A CB 1 ATOM 3807 C CG . PRO A 1 494 ? 66.751 -13.781 -25.785 1.00 8.91 ? 494 PRO A CG 1 ATOM 3808 C CD . PRO A 1 494 ? 65.966 -14.160 -27.030 1.00 8.70 ? 494 PRO A CD 1 ATOM 3809 N N . ALA A 1 495 ? 63.707 -13.665 -24.292 1.00 7.98 ? 495 ALA A N 1 ATOM 3810 C CA . ALA A 1 495 ? 62.859 -12.991 -23.319 1.00 7.65 ? 495 ALA A CA 1 ATOM 3811 C C . ALA A 1 495 ? 62.063 -11.930 -24.060 1.00 7.94 ? 495 ALA A C 1 ATOM 3812 O O . ALA A 1 495 ? 62.118 -11.854 -25.288 1.00 8.77 ? 495 ALA A O 1 ATOM 3813 C CB . ALA A 1 495 ? 63.719 -12.342 -22.236 1.00 7.82 ? 495 ALA A CB 1 ATOM 3814 N N . SER A 1 496 ? 61.327 -11.110 -23.317 1.00 8.02 ? 496 SER A N 1 ATOM 3815 C CA . SER A 1 496 ? 60.540 -10.044 -23.929 1.00 7.25 ? 496 SER A CA 1 ATOM 3816 C C . SER A 1 496 ? 61.481 -9.061 -24.622 1.00 9.56 ? 496 SER A C 1 ATOM 3817 O O . SER A 1 496 ? 61.140 -8.461 -25.644 1.00 8.73 ? 496 SER A O 1 ATOM 3818 C CB . SER A 1 496 ? 59.723 -9.312 -22.861 1.00 6.98 ? 496 SER A CB 1 ATOM 3819 O OG . SER A 1 496 ? 60.568 -8.741 -21.877 1.00 8.30 ? 496 SER A OG 1 ATOM 3820 N N . HIS A 1 497 ? 62.671 -8.910 -24.050 1.00 8.24 ? 497 HIS A N 1 ATOM 3821 C CA . HIS A 1 497 ? 63.693 -8.014 -24.569 1.00 7.37 ? 497 HIS A CA 1 ATOM 3822 C C . HIS A 1 497 ? 64.983 -8.820 -24.509 1.00 7.03 ? 497 HIS A C 1 ATOM 3823 O O . HIS A 1 497 ? 65.437 -9.214 -23.435 1.00 7.49 ? 497 HIS A O 1 ATOM 3824 C CB . HIS A 1 497 ? 63.731 -6.751 -23.713 1.00 7.48 ? 497 HIS A CB 1 ATOM 3825 C CG . HIS A 1 497 ? 62.461 -5.957 -23.786 1.00 8.63 ? 497 HIS A CG 1 ATOM 3826 N ND1 . HIS A 1 497 ? 61.308 -6.329 -23.125 1.00 8.75 ? 497 HIS A ND1 1 ATOM 3827 C CD2 . HIS A 1 497 ? 62.142 -4.857 -24.508 1.00 9.39 ? 497 HIS A CD2 1 ATOM 3828 C CE1 . HIS A 1 497 ? 60.335 -5.492 -23.439 1.00 10.71 ? 497 HIS A CE1 1 ATOM 3829 N NE2 . HIS A 1 497 ? 60.814 -4.590 -24.278 1.00 9.29 ? 497 HIS A NE2 1 ATOM 3830 N N . PRO A 1 498 ? 65.591 -9.071 -25.678 1.00 7.86 ? 498 PRO A N 1 ATOM 3831 C CA . PRO A 1 498 ? 66.816 -9.855 -25.831 1.00 6.88 ? 498 PRO A CA 1 ATOM 3832 C C . PRO A 1 498 ? 68.209 -9.293 -25.596 1.00 7.14 ? 498 PRO A C 1 ATOM 3833 O O . PRO A 1 498 ? 69.158 -10.072 -25.563 1.00 7.09 ? 498 PRO A O 1 ATOM 3834 C CB . PRO A 1 498 ? 66.679 -10.373 -27.251 1.00 7.68 ? 498 PRO A CB 1 ATOM 3835 C CG . PRO A 1 498 ? 66.191 -9.130 -27.955 1.00 8.04 ? 498 PRO A CG 1 ATOM 3836 C CD . PRO A 1 498 ? 65.119 -8.600 -26.997 1.00 7.44 ? 498 PRO A CD 1 ATOM 3837 N N . GLN A 1 499 ? 68.371 -7.985 -25.431 1.00 5.58 ? 499 GLN A N 1 ATOM 3838 C CA . GLN A 1 499 ? 69.733 -7.479 -25.267 1.00 5.86 ? 499 GLN A CA 1 ATOM 3839 C C . GLN A 1 499 ? 70.486 -8.092 -24.087 1.00 6.94 ? 499 GLN A C 1 ATOM 3840 O O . GLN A 1 499 ? 71.681 -8.366 -24.193 1.00 8.11 ? 499 GLN A O 1 ATOM 3841 C CB . GLN A 1 499 ? 69.757 -5.940 -25.191 1.00 7.09 ? 499 GLN A CB 1 ATOM 3842 C CG . GLN A 1 499 ? 69.477 -5.308 -23.833 1.00 6.38 ? 499 GLN A CG 1 ATOM 3843 C CD . GLN A 1 499 ? 69.799 -3.818 -23.844 1.00 7.50 ? 499 GLN A CD 1 ATOM 3844 O OE1 . GLN A 1 499 ? 70.753 -3.389 -24.497 1.00 9.08 ? 499 GLN A OE1 1 ATOM 3845 N NE2 . GLN A 1 499 ? 69.018 -3.028 -23.113 1.00 9.16 ? 499 GLN A NE2 1 ATOM 3846 N N . GLY A 1 500 ? 69.799 -8.329 -22.976 1.00 6.46 ? 500 GLY A N 1 ATOM 3847 C CA . GLY A 1 500 ? 70.474 -8.918 -21.828 1.00 7.08 ? 500 GLY A CA 1 ATOM 3848 C C . GLY A 1 500 ? 71.123 -10.248 -22.174 1.00 7.51 ? 500 GLY A C 1 ATOM 3849 O O . GLY A 1 500 ? 72.266 -10.523 -21.792 1.00 6.53 ? 500 GLY A O 1 ATOM 3850 N N . PHE A 1 501 ? 70.394 -11.083 -22.906 1.00 7.52 ? 501 PHE A N 1 ATOM 3851 C CA . PHE A 1 501 ? 70.907 -12.388 -23.303 1.00 7.43 ? 501 PHE A CA 1 ATOM 3852 C C . PHE A 1 501 ? 72.079 -12.261 -24.283 1.00 7.10 ? 501 PHE A C 1 ATOM 3853 O O . PHE A 1 501 ? 73.085 -12.960 -24.151 1.00 8.73 ? 501 PHE A O 1 ATOM 3854 C CB . PHE A 1 501 ? 69.789 -13.220 -23.940 1.00 8.95 ? 501 PHE A CB 1 ATOM 3855 C CG . PHE A 1 501 ? 70.236 -14.577 -24.409 1.00 8.54 ? 501 PHE A CG 1 ATOM 3856 C CD1 . PHE A 1 501 ? 70.472 -15.602 -23.498 1.00 9.29 ? 501 PHE A CD1 1 ATOM 3857 C CD2 . PHE A 1 501 ? 70.446 -14.820 -25.763 1.00 8.03 ? 501 PHE A CD2 1 ATOM 3858 C CE1 . PHE A 1 501 ? 70.913 -16.852 -23.932 1.00 9.36 ? 501 PHE A CE1 1 ATOM 3859 C CE2 . PHE A 1 501 ? 70.887 -16.064 -26.208 1.00 8.82 ? 501 PHE A CE2 1 ATOM 3860 C CZ . PHE A 1 501 ? 71.120 -17.082 -25.292 1.00 10.21 ? 501 PHE A CZ 1 ATOM 3861 N N . TYR A 1 502 ? 71.959 -11.369 -25.262 1.00 7.73 ? 502 TYR A N 1 ATOM 3862 C CA . TYR A 1 502 ? 73.030 -11.201 -26.242 1.00 7.60 ? 502 TYR A CA 1 ATOM 3863 C C . TYR A 1 502 ? 74.282 -10.571 -25.624 1.00 8.45 ? 502 TYR A C 1 ATOM 3864 O O . TYR A 1 502 ? 75.399 -10.876 -26.044 1.00 8.94 ? 502 TYR A O 1 ATOM 3865 C CB . TYR A 1 502 ? 72.538 -10.373 -27.436 1.00 7.43 ? 502 TYR A CB 1 ATOM 3866 C CG . TYR A 1 502 ? 71.368 -10.994 -28.184 1.00 7.99 ? 502 TYR A CG 1 ATOM 3867 C CD1 . TYR A 1 502 ? 70.419 -10.191 -28.814 1.00 9.03 ? 502 TYR A CD1 1 ATOM 3868 C CD2 . TYR A 1 502 ? 71.187 -12.379 -28.227 1.00 8.95 ? 502 TYR A CD2 1 ATOM 3869 C CE1 . TYR A 1 502 ? 69.312 -10.746 -29.459 1.00 8.77 ? 502 TYR A CE1 1 ATOM 3870 C CE2 . TYR A 1 502 ? 70.077 -12.946 -28.876 1.00 7.77 ? 502 TYR A CE2 1 ATOM 3871 C CZ . TYR A 1 502 ? 69.146 -12.120 -29.483 1.00 9.78 ? 502 TYR A CZ 1 ATOM 3872 O OH . TYR A 1 502 ? 68.029 -12.654 -30.087 1.00 9.63 ? 502 TYR A OH 1 ATOM 3873 N N . LEU A 1 503 ? 74.102 -9.693 -24.637 1.00 8.13 ? 503 LEU A N 1 ATOM 3874 C CA . LEU A 1 503 ? 75.248 -9.072 -23.962 1.00 7.52 ? 503 LEU A CA 1 ATOM 3875 C C . LEU A 1 503 ? 75.985 -10.176 -23.206 1.00 8.02 ? 503 LEU A C 1 ATOM 3876 O O . LEU A 1 503 ? 77.209 -10.282 -23.266 1.00 7.57 ? 503 LEU A O 1 ATOM 3877 C CB . LEU A 1 503 ? 74.781 -7.998 -22.970 1.00 7.69 ? 503 LEU A CB 1 ATOM 3878 C CG . LEU A 1 503 ? 74.233 -6.694 -23.561 1.00 8.47 ? 503 LEU A CG 1 ATOM 3879 C CD1 . LEU A 1 503 ? 73.357 -5.993 -22.536 1.00 9.37 ? 503 LEU A CD1 1 ATOM 3880 C CD2 . LEU A 1 503 ? 75.387 -5.800 -24.002 1.00 8.15 ? 503 LEU A CD2 1 ATOM 3881 N N . MET A 1 504 ? 75.216 -10.998 -22.500 1.00 8.64 ? 504 MET A N 1 ATOM 3882 C CA . MET A 1 504 ? 75.760 -12.108 -21.727 1.00 8.32 ? 504 MET A CA 1 ATOM 3883 C C . MET A 1 504 ? 76.466 -13.098 -22.650 1.00 8.86 ? 504 MET A C 1 ATOM 3884 O O . MET A 1 504 ? 77.573 -13.548 -22.363 1.00 7.82 ? 504 MET A O 1 ATOM 3885 C CB . MET A 1 504 ? 74.617 -12.800 -20.970 1.00 8.14 ? 504 MET A CB 1 ATOM 3886 C CG . MET A 1 504 ? 75.006 -14.013 -20.127 1.00 10.12 ? 504 MET A CG 1 ATOM 3887 S SD . MET A 1 504 ? 75.213 -15.554 -21.047 1.00 9.85 ? 504 MET A SD 1 ATOM 3888 C CE . MET A 1 504 ? 73.531 -15.868 -21.608 1.00 11.36 ? 504 MET A CE 1 ATOM 3889 N N . LEU A 1 505 ? 75.831 -13.414 -23.775 1.00 7.92 ? 505 LEU A N 1 ATOM 3890 C CA . LEU A 1 505 ? 76.391 -14.364 -24.732 1.00 6.99 ? 505 LEU A CA 1 ATOM 3891 C C . LEU A 1 505 ? 77.807 -14.007 -25.174 1.00 8.42 ? 505 LEU A C 1 ATOM 3892 O O . LEU A 1 505 ? 78.667 -14.883 -25.296 1.00 7.68 ? 505 LEU A O 1 ATOM 3893 C CB . LEU A 1 505 ? 75.483 -14.464 -25.965 1.00 7.72 ? 505 LEU A CB 1 ATOM 3894 C CG . LEU A 1 505 ? 75.879 -15.511 -27.007 1.00 9.19 ? 505 LEU A CG 1 ATOM 3895 C CD1 . LEU A 1 505 ? 75.694 -16.901 -26.408 1.00 10.55 ? 505 LEU A CD1 1 ATOM 3896 C CD2 . LEU A 1 505 ? 75.020 -15.357 -28.263 1.00 11.68 ? 505 LEU A CD2 1 ATOM 3897 N N . GLY A 1 506 ? 78.046 -12.721 -25.412 1.00 6.94 ? 506 GLY A N 1 ATOM 3898 C CA . GLY A 1 506 ? 79.355 -12.280 -25.854 1.00 6.81 ? 506 GLY A CA 1 ATOM 3899 C C . GLY A 1 506 ? 80.458 -12.707 -24.906 1.00 8.30 ? 506 GLY A C 1 ATOM 3900 O O . GLY A 1 506 ? 81.420 -13.365 -25.312 1.00 7.85 ? 506 GLY A O 1 ATOM 3901 N N . ARG A 1 507 ? 80.327 -12.337 -23.638 1.00 8.09 ? 507 ARG A N 1 ATOM 3902 C CA . ARG A 1 507 ? 81.343 -12.706 -22.662 1.00 8.73 ? 507 ARG A CA 1 ATOM 3903 C C . ARG A 1 507 ? 81.339 -14.202 -22.371 1.00 10.20 ? 507 ARG A C 1 ATOM 3904 O O . ARG A 1 507 ? 82.400 -14.794 -22.184 1.00 9.38 ? 507 ARG A O 1 ATOM 3905 C CB . ARG A 1 507 ? 81.159 -11.936 -21.355 1.00 10.12 ? 507 ARG A CB 1 ATOM 3906 C CG . ARG A 1 507 ? 82.118 -12.404 -20.260 1.00 10.65 ? 507 ARG A CG 1 ATOM 3907 C CD . ARG A 1 507 ? 82.066 -11.492 -19.063 1.00 11.60 ? 507 ARG A CD 1 ATOM 3908 N NE . ARG A 1 507 ? 82.842 -11.992 -17.929 1.00 9.79 ? 507 ARG A NE 1 ATOM 3909 C CZ . ARG A 1 507 ? 84.165 -11.918 -17.815 1.00 10.65 ? 507 ARG A CZ 1 ATOM 3910 N NH1 . ARG A 1 507 ? 84.899 -11.362 -18.773 1.00 9.78 ? 507 ARG A NH1 1 ATOM 3911 N NH2 . ARG A 1 507 ? 84.753 -12.387 -16.720 1.00 10.56 ? 507 ARG A NH2 1 ATOM 3912 N N . TYR A 1 508 ? 80.153 -14.805 -22.326 1.00 10.42 ? 508 TYR A N 1 ATOM 3913 C CA . TYR A 1 508 ? 80.040 -16.238 -22.063 1.00 9.43 ? 508 TYR A CA 1 ATOM 3914 C C . TYR A 1 508 ? 80.929 -17.042 -23.013 1.00 10.46 ? 508 TYR A C 1 ATOM 3915 O O . TYR A 1 508 ? 81.733 -17.874 -22.581 1.00 9.62 ? 508 TYR A O 1 ATOM 3916 C CB . TYR A 1 508 ? 78.592 -16.705 -22.234 1.00 10.55 ? 508 TYR A CB 1 ATOM 3917 C CG . TYR A 1 508 ? 78.411 -18.182 -21.965 1.00 9.36 ? 508 TYR A CG 1 ATOM 3918 C CD1 . TYR A 1 508 ? 78.171 -18.651 -20.672 1.00 11.26 ? 508 TYR A CD1 1 ATOM 3919 C CD2 . TYR A 1 508 ? 78.521 -19.115 -22.995 1.00 9.74 ? 508 TYR A CD2 1 ATOM 3920 C CE1 . TYR A 1 508 ? 78.048 -20.015 -20.412 1.00 13.02 ? 508 TYR A CE1 1 ATOM 3921 C CE2 . TYR A 1 508 ? 78.399 -20.480 -22.746 1.00 11.22 ? 508 TYR A CE2 1 ATOM 3922 C CZ . TYR A 1 508 ? 78.165 -20.922 -21.454 1.00 11.02 ? 508 TYR A CZ 1 ATOM 3923 O OH . TYR A 1 508 ? 78.058 -22.273 -21.205 1.00 12.34 ? 508 TYR A OH 1 ATOM 3924 N N . VAL A 1 509 ? 80.773 -16.805 -24.312 1.00 8.56 ? 509 VAL A N 1 ATOM 3925 C CA . VAL A 1 509 ? 81.576 -17.526 -25.289 1.00 8.61 ? 509 VAL A CA 1 ATOM 3926 C C . VAL A 1 509 ? 83.039 -17.131 -25.153 1.00 8.82 ? 509 VAL A C 1 ATOM 3927 O O . VAL A 1 509 ? 83.934 -17.949 -25.371 1.00 9.88 ? 509 VAL A O 1 ATOM 3928 C CB . VAL A 1 509 ? 81.091 -17.258 -26.726 1.00 8.29 ? 509 VAL A CB 1 ATOM 3929 C CG1 . VAL A 1 509 ? 81.964 -18.013 -27.718 1.00 8.88 ? 509 VAL A CG1 1 ATOM 3930 C CG2 . VAL A 1 509 ? 79.639 -17.701 -26.865 1.00 8.28 ? 509 VAL A CG2 1 ATOM 3931 N N . GLY A 1 510 ? 83.282 -15.876 -24.789 1.00 8.19 ? 510 GLY A N 1 ATOM 3932 C CA . GLY A 1 510 ? 84.647 -15.422 -24.606 1.00 9.68 ? 510 GLY A CA 1 ATOM 3933 C C . GLY A 1 510 ? 85.326 -16.248 -23.529 1.00 9.58 ? 510 GLY A C 1 ATOM 3934 O O . GLY A 1 510 ? 86.469 -16.675 -23.693 1.00 10.95 ? 510 GLY A O 1 ATOM 3935 N N . ILE A 1 511 ? 84.616 -16.477 -22.426 1.00 9.50 ? 511 ILE A N 1 ATOM 3936 C CA . ILE A 1 511 ? 85.153 -17.262 -21.319 1.00 8.90 ? 511 ILE A CA 1 ATOM 3937 C C . ILE A 1 511 ? 85.356 -18.718 -21.736 1.00 10.57 ? 511 ILE A C 1 ATOM 3938 O O . ILE A 1 511 ? 86.330 -19.351 -21.333 1.00 11.53 ? 511 ILE A O 1 ATOM 3939 C CB . ILE A 1 511 ? 84.219 -17.218 -20.087 1.00 8.96 ? 511 ILE A CB 1 ATOM 3940 C CG1 . ILE A 1 511 ? 84.221 -15.813 -19.478 1.00 10.22 ? 511 ILE A CG1 1 ATOM 3941 C CG2 . ILE A 1 511 ? 84.674 -18.238 -19.050 1.00 11.29 ? 511 ILE A CG2 1 ATOM 3942 C CD1 . ILE A 1 511 ? 85.585 -15.357 -18.976 1.00 10.86 ? 511 ILE A CD1 1 ATOM 3943 N N . LYS A 1 512 ? 84.438 -19.253 -22.537 1.00 10.12 ? 512 LYS A N 1 ATOM 3944 C CA . LYS A 1 512 ? 84.573 -20.634 -22.993 1.00 10.16 ? 512 LYS A CA 1 ATOM 3945 C C . LYS A 1 512 ? 85.838 -20.773 -23.834 1.00 11.38 ? 512 LYS A C 1 ATOM 3946 O O . LYS A 1 512 ? 86.549 -21.776 -23.742 1.00 12.61 ? 512 LYS A O 1 ATOM 3947 C CB . LYS A 1 512 ? 83.352 -21.059 -23.816 1.00 12.31 ? 512 LYS A CB 1 ATOM 3948 C CG . LYS A 1 512 ? 82.051 -21.086 -23.026 1.00 13.81 ? 512 LYS A CG 1 ATOM 3949 C CD . LYS A 1 512 ? 82.094 -22.097 -21.884 1.00 17.85 ? 512 LYS A CD 1 ATOM 3950 C CE . LYS A 1 512 ? 82.194 -23.520 -22.402 1.00 19.63 ? 512 LYS A CE 1 ATOM 3951 N NZ . LYS A 1 512 ? 82.027 -24.514 -21.302 1.00 22.84 ? 512 LYS A NZ 1 ATOM 3952 N N . ILE A 1 513 ? 86.120 -19.763 -24.652 1.00 11.35 ? 513 ILE A N 1 ATOM 3953 C CA . ILE A 1 513 ? 87.313 -19.791 -25.493 1.00 10.79 ? 513 ILE A CA 1 ATOM 3954 C C . ILE A 1 513 ? 88.571 -19.729 -24.624 1.00 11.82 ? 513 ILE A C 1 ATOM 3955 O O . ILE A 1 513 ? 89.538 -20.448 -24.874 1.00 12.13 ? 513 ILE A O 1 ATOM 3956 C CB . ILE A 1 513 ? 87.314 -18.618 -26.505 1.00 9.93 ? 513 ILE A CB 1 ATOM 3957 C CG1 . ILE A 1 513 ? 86.205 -18.827 -27.540 1.00 10.95 ? 513 ILE A CG1 1 ATOM 3958 C CG2 . ILE A 1 513 ? 88.663 -18.535 -27.212 1.00 9.38 ? 513 ILE A CG2 1 ATOM 3959 C CD1 . ILE A 1 513 ? 86.004 -17.649 -28.471 1.00 11.14 ? 513 ILE A CD1 1 ATOM 3960 N N . LEU A 1 514 ? 88.558 -18.878 -23.602 1.00 11.82 ? 514 LEU A N 1 ATOM 3961 C CA . LEU A 1 514 ? 89.709 -18.766 -22.712 1.00 13.37 ? 514 LEU A CA 1 ATOM 3962 C C . LEU A 1 514 ? 89.943 -20.068 -21.955 1.00 14.54 ? 514 LEU A C 1 ATOM 3963 O O . LEU A 1 514 ? 91.086 -20.480 -21.762 1.00 15.78 ? 514 LEU A O 1 ATOM 3964 C CB . LEU A 1 514 ? 89.521 -17.620 -21.712 1.00 13.27 ? 514 LEU A CB 1 ATOM 3965 C CG . LEU A 1 514 ? 89.582 -16.208 -22.299 1.00 13.61 ? 514 LEU A CG 1 ATOM 3966 C CD1 . LEU A 1 514 ? 89.505 -15.184 -21.175 1.00 14.46 ? 514 LEU A CD1 1 ATOM 3967 C CD2 . LEU A 1 514 ? 90.876 -16.035 -23.088 1.00 13.19 ? 514 LEU A CD2 1 ATOM 3968 N N . GLN A 1 515 ? 88.864 -20.719 -21.528 1.00 14.82 ? 515 GLN A N 1 ATOM 3969 C CA . GLN A 1 515 ? 89.001 -21.977 -20.800 1.00 16.86 ? 515 GLN A CA 1 ATOM 3970 C C . GLN A 1 515 ? 89.580 -23.039 -21.728 1.00 17.39 ? 515 GLN A C 1 ATOM 3971 O O . GLN A 1 515 ? 90.367 -23.887 -21.303 1.00 18.03 ? 515 GLN A O 1 ATOM 3972 C CB . GLN A 1 515 ? 87.645 -22.431 -20.249 1.00 16.98 ? 515 GLN A CB 1 ATOM 3973 C CG . GLN A 1 515 ? 86.991 -21.404 -19.336 1.00 18.03 ? 515 GLN A CG 1 ATOM 3974 C CD . GLN A 1 515 ? 85.758 -21.934 -18.624 1.00 19.49 ? 515 GLN A CD 1 ATOM 3975 O OE1 . GLN A 1 515 ? 85.003 -22.735 -19.173 1.00 20.12 ? 515 GLN A OE1 1 ATOM 3976 N NE2 . GLN A 1 515 ? 85.540 -21.471 -17.399 1.00 20.86 ? 515 GLN A NE2 1 ATOM 3977 N N . GLU A 1 516 ? 89.197 -22.977 -22.998 1.00 16.92 ? 516 GLU A N 1 ATOM 3978 C CA . GLU A 1 516 ? 89.685 -23.920 -23.991 1.00 19.13 ? 516 GLU A CA 1 ATOM 3979 C C . GLU A 1 516 ? 91.177 -23.696 -24.239 1.00 18.99 ? 516 GLU A C 1 ATOM 3980 O O . GLU A 1 516 ? 91.938 -24.657 -24.361 1.00 19.11 ? 516 GLU A O 1 ATOM 3981 C CB . GLU A 1 516 ? 88.897 -23.760 -25.295 1.00 20.34 ? 516 GLU A CB 1 ATOM 3982 C CG . GLU A 1 516 ? 89.145 -24.858 -26.305 1.00 24.64 ? 516 GLU A CG 1 ATOM 3983 C CD . GLU A 1 516 ? 88.189 -24.785 -27.474 1.00 27.34 ? 516 GLU A CD 1 ATOM 3984 O OE1 . GLU A 1 516 ? 88.292 -23.832 -28.274 1.00 28.48 ? 516 GLU A OE1 1 ATOM 3985 O OE2 . GLU A 1 516 ? 87.327 -25.679 -27.583 1.00 29.98 ? 516 GLU A OE2 1 ATOM 3986 N N . ARG A 1 517 ? 91.593 -22.431 -24.308 1.00 18.00 ? 517 ARG A N 1 ATOM 3987 C CA . ARG A 1 517 ? 93.000 -22.098 -24.528 1.00 19.71 ? 517 ARG A CA 1 ATOM 3988 C C . ARG A 1 517 ? 93.829 -22.515 -23.314 1.00 21.09 ? 517 ARG A C 1 ATOM 3989 O O . ARG A 1 517 ? 94.988 -22.909 -23.450 1.00 22.28 ? 517 ARG A O 1 ATOM 3990 C CB . ARG A 1 517 ? 93.175 -20.591 -24.785 1.00 18.30 ? 517 ARG A CB 1 ATOM 3991 C CG . ARG A 1 517 ? 92.660 -20.102 -26.145 1.00 17.76 ? 517 ARG A CG 1 ATOM 3992 C CD . ARG A 1 517 ? 93.420 -20.721 -27.320 1.00 17.92 ? 517 ARG A CD 1 ATOM 3993 N NE . ARG A 1 517 ? 94.845 -20.386 -27.338 1.00 18.09 ? 517 ARG A NE 1 ATOM 3994 C CZ . ARG A 1 517 ? 95.371 -19.305 -27.911 1.00 18.59 ? 517 ARG A CZ 1 ATOM 3995 N NH1 . ARG A 1 517 ? 94.595 -18.422 -28.531 1.00 17.26 ? 517 ARG A NH1 1 ATOM 3996 N NH2 . ARG A 1 517 ? 96.685 -19.113 -27.875 1.00 16.96 ? 517 ARG A NH2 1 ATOM 3997 N N . SER A 1 518 ? 93.230 -22.436 -22.129 1.00 22.06 ? 518 SER A N 1 ATOM 3998 C CA . SER A 1 518 ? 93.926 -22.817 -20.903 1.00 24.62 ? 518 SER A CA 1 ATOM 3999 C C . SER A 1 518 ? 94.256 -24.300 -20.906 1.00 25.80 ? 518 SER A C 1 ATOM 4000 O O . SER A 1 518 ? 95.352 -24.710 -20.512 1.00 26.47 ? 518 SER A O 1 ATOM 4001 C CB . SER A 1 518 ? 93.070 -22.499 -19.675 1.00 25.69 ? 518 SER A CB 1 ATOM 4002 O OG . SER A 1 518 ? 93.224 -21.147 -19.285 1.00 29.08 ? 518 SER A OG 1 ATOM 4003 N N . ALA A 1 519 ? 93.298 -25.098 -21.359 1.00 26.54 ? 519 ALA A N 1 ATOM 4004 C CA . ALA A 1 519 ? 93.462 -26.541 -21.402 1.00 28.15 ? 519 ALA A CA 1 ATOM 4005 C C . ALA A 1 519 ? 94.471 -27.000 -22.442 1.00 29.92 ? 519 ALA A C 1 ATOM 4006 O O . ALA A 1 519 ? 95.097 -28.044 -22.275 1.00 30.11 ? 519 ALA A O 1 ATOM 4007 C CB . ALA A 1 519 ? 92.112 -27.209 -21.659 1.00 28.49 ? 519 ALA A CB 1 ATOM 4008 N N . SER A 1 520 ? 94.635 -26.220 -23.507 1.00 31.08 ? 520 SER A N 1 ATOM 4009 C CA . SER A 1 520 ? 95.558 -26.587 -24.574 1.00 32.79 ? 520 SER A CA 1 ATOM 4010 C C . SER A 1 520 ? 96.933 -25.944 -24.469 1.00 33.34 ? 520 SER A C 1 ATOM 4011 O O . SER A 1 520 ? 97.767 -26.137 -25.349 1.00 33.99 ? 520 SER A O 1 ATOM 4012 C CB . SER A 1 520 ? 94.945 -26.259 -25.944 1.00 32.24 ? 520 SER A CB 1 ATOM 4013 O OG . SER A 1 520 ? 94.846 -24.858 -26.138 1.00 32.51 ? 520 SER A OG 1 ATOM 4014 N N . ASP A 1 521 ? 97.174 -25.172 -23.412 1.00 34.61 ? 521 ASP A N 1 ATOM 4015 C CA . ASP A 1 521 ? 98.481 -24.538 -23.239 1.00 35.80 ? 521 ASP A CA 1 ATOM 4016 C C . ASP A 1 521 ? 99.562 -25.593 -23.022 1.00 36.53 ? 521 ASP A C 1 ATOM 4017 O O . ASP A 1 521 ? 100.757 -25.226 -22.989 1.00 37.38 ? 521 ASP A O 1 ATOM 4018 C CB . ASP A 1 521 ? 98.482 -23.572 -22.047 1.00 35.47 ? 521 ASP A CB 1 ATOM 4019 C CG . ASP A 1 521 ? 97.888 -22.224 -22.386 1.00 36.76 ? 521 ASP A CG 1 ATOM 4020 O OD1 . ASP A 1 521 ? 98.333 -21.619 -23.386 1.00 35.50 ? 521 ASP A OD1 1 ATOM 4021 O OD2 . ASP A 1 521 ? 96.986 -21.769 -21.651 1.00 36.83 ? 521 ASP A OD2 1 ATOM 4022 O OXT . ASP A 1 521 ? 99.201 -26.779 -22.881 1.00 37.08 ? 521 ASP A OXT 1 ATOM 4023 N N . LEU B 1 1 ? 49.242 42.137 8.648 1.00 15.05 ? 1 LEU B N 1 ATOM 4024 C CA . LEU B 1 1 ? 48.783 43.385 7.974 1.00 14.77 ? 1 LEU B CA 1 ATOM 4025 C C . LEU B 1 1 ? 49.818 44.492 8.129 1.00 15.00 ? 1 LEU B C 1 ATOM 4026 O O . LEU B 1 1 ? 50.619 44.485 9.068 1.00 16.82 ? 1 LEU B O 1 ATOM 4027 C CB . LEU B 1 1 ? 47.444 43.840 8.561 1.00 16.06 ? 1 LEU B CB 1 ATOM 4028 C CG . LEU B 1 1 ? 46.311 42.814 8.477 1.00 16.73 ? 1 LEU B CG 1 ATOM 4029 C CD1 . LEU B 1 1 ? 45.096 43.324 9.234 1.00 19.61 ? 1 LEU B CD1 1 ATOM 4030 C CD2 . LEU B 1 1 ? 45.967 42.552 7.021 1.00 19.16 ? 1 LEU B CD2 1 ATOM 4031 N N . ALA B 1 2 ? 49.793 45.443 7.203 1.00 13.16 ? 2 ALA B N 1 ATOM 4032 C CA . ALA B 1 2 ? 50.733 46.554 7.209 1.00 13.57 ? 2 ALA B CA 1 ATOM 4033 C C . ALA B 1 2 ? 50.164 47.793 7.883 1.00 13.39 ? 2 ALA B C 1 ATOM 4034 O O . ALA B 1 2 ? 48.986 47.842 8.238 1.00 14.20 ? 2 ALA B O 1 ATOM 4035 C CB . ALA B 1 2 ? 51.142 46.887 5.779 1.00 13.98 ? 2 ALA B CB 1 ATOM 4036 N N . THR B 1 3 ? 51.023 48.793 8.053 1.00 13.48 ? 3 THR B N 1 ATOM 4037 C CA . THR B 1 3 ? 50.642 50.055 8.668 1.00 16.32 ? 3 THR B CA 1 ATOM 4038 C C . THR B 1 3 ? 50.776 51.158 7.626 1.00 15.58 ? 3 THR B C 1 ATOM 4039 O O . THR B 1 3 ? 51.775 51.226 6.910 1.00 15.94 ? 3 THR B O 1 ATOM 4040 C CB . THR B 1 3 ? 51.553 50.385 9.865 1.00 18.29 ? 3 THR B CB 1 ATOM 4041 O OG1 . THR B 1 3 ? 51.472 49.332 10.832 1.00 20.80 ? 3 THR B OG1 1 ATOM 4042 C CG2 . THR B 1 3 ? 51.129 51.694 10.511 1.00 20.51 ? 3 THR B CG2 1 ATOM 4043 N N . THR B 1 4 ? 49.762 52.013 7.542 1.00 16.35 ? 4 THR B N 1 ATOM 4044 C CA . THR B 1 4 ? 49.746 53.118 6.588 1.00 15.87 ? 4 THR B CA 1 ATOM 4045 C C . THR B 1 4 ? 51.096 53.820 6.445 1.00 15.94 ? 4 THR B C 1 ATOM 4046 O O . THR B 1 4 ? 51.734 54.172 7.438 1.00 16.90 ? 4 THR B O 1 ATOM 4047 C CB . THR B 1 4 ? 48.680 54.161 6.988 1.00 16.53 ? 4 THR B CB 1 ATOM 4048 O OG1 . THR B 1 4 ? 47.388 53.544 6.969 1.00 18.72 ? 4 THR B OG1 1 ATOM 4049 C CG2 . THR B 1 4 ? 48.688 55.340 6.027 1.00 17.81 ? 4 THR B CG2 1 ATOM 4050 N N . SER B 1 5 ? 51.518 54.025 5.200 1.00 16.05 ? 5 SER B N 1 ATOM 4051 C CA . SER B 1 5 ? 52.787 54.687 4.898 1.00 16.69 ? 5 SER B CA 1 ATOM 4052 C C . SER B 1 5 ? 52.812 55.075 3.425 1.00 16.47 ? 5 SER B C 1 ATOM 4053 O O . SER B 1 5 ? 51.923 54.694 2.669 1.00 14.21 ? 5 SER B O 1 ATOM 4054 C CB . SER B 1 5 ? 53.957 53.743 5.178 1.00 17.48 ? 5 SER B CB 1 ATOM 4055 O OG . SER B 1 5 ? 53.969 52.670 4.247 1.00 20.13 ? 5 SER B OG 1 ATOM 4056 N N . ASP B 1 6 ? 53.828 55.828 3.015 1.00 16.29 ? 6 ASP B N 1 ATOM 4057 C CA . ASP B 1 6 ? 53.931 56.216 1.619 1.00 16.31 ? 6 ASP B CA 1 ATOM 4058 C C . ASP B 1 6 ? 54.257 54.986 0.788 1.00 15.19 ? 6 ASP B C 1 ATOM 4059 O O . ASP B 1 6 ? 54.773 53.995 1.305 1.00 14.69 ? 6 ASP B O 1 ATOM 4060 C CB . ASP B 1 6 ? 55.047 57.247 1.405 1.00 18.80 ? 6 ASP B CB 1 ATOM 4061 C CG . ASP B 1 6 ? 54.841 58.519 2.192 1.00 21.63 ? 6 ASP B CG 1 ATOM 4062 O OD1 . ASP B 1 6 ? 53.686 58.836 2.543 1.00 21.77 ? 6 ASP B OD1 1 ATOM 4063 O OD2 . ASP B 1 6 ? 55.851 59.216 2.429 1.00 23.84 ? 6 ASP B OD2 1 ATOM 4064 N N . HIS B 1 7 ? 53.948 55.051 -0.500 1.00 14.98 ? 7 HIS B N 1 ATOM 4065 C CA . HIS B 1 7 ? 54.256 53.950 -1.398 1.00 15.14 ? 7 HIS B CA 1 ATOM 4066 C C . HIS B 1 7 ? 55.784 53.850 -1.365 1.00 15.05 ? 7 HIS B C 1 ATOM 4067 O O . HIS B 1 7 ? 56.477 54.845 -1.582 1.00 15.30 ? 7 HIS B O 1 ATOM 4068 C CB . HIS B 1 7 ? 53.779 54.275 -2.812 1.00 13.89 ? 7 HIS B CB 1 ATOM 4069 C CG . HIS B 1 7 ? 53.842 53.110 -3.750 1.00 14.32 ? 7 HIS B CG 1 ATOM 4070 N ND1 . HIS B 1 7 ? 52.783 52.249 -3.940 1.00 14.07 ? 7 HIS B ND1 1 ATOM 4071 C CD2 . HIS B 1 7 ? 54.835 52.669 -4.558 1.00 14.33 ? 7 HIS B CD2 1 ATOM 4072 C CE1 . HIS B 1 7 ? 53.118 51.331 -4.829 1.00 14.16 ? 7 HIS B CE1 1 ATOM 4073 N NE2 . HIS B 1 7 ? 54.358 51.564 -5.220 1.00 14.99 ? 7 HIS B NE2 1 ATOM 4074 N N . ASP B 1 8 ? 56.302 52.656 -1.091 1.00 14.90 ? 8 ASP B N 1 ATOM 4075 C CA . ASP B 1 8 ? 57.746 52.435 -0.989 1.00 15.66 ? 8 ASP B CA 1 ATOM 4076 C C . ASP B 1 8 ? 58.448 52.241 -2.333 1.00 15.37 ? 8 ASP B C 1 ATOM 4077 O O . ASP B 1 8 ? 58.375 51.167 -2.929 1.00 14.88 ? 8 ASP B O 1 ATOM 4078 C CB . ASP B 1 8 ? 58.012 51.218 -0.099 1.00 15.93 ? 8 ASP B CB 1 ATOM 4079 C CG . ASP B 1 8 ? 59.469 51.095 0.314 1.00 16.15 ? 8 ASP B CG 1 ATOM 4080 O OD1 . ASP B 1 8 ? 60.329 51.765 -0.298 1.00 16.97 ? 8 ASP B OD1 1 ATOM 4081 O OD2 . ASP B 1 8 ? 59.751 50.316 1.250 1.00 15.31 ? 8 ASP B OD2 1 ATOM 4082 N N . PHE B 1 9 ? 59.145 53.277 -2.797 1.00 13.85 ? 9 PHE B N 1 ATOM 4083 C CA . PHE B 1 9 ? 59.867 53.209 -4.066 1.00 13.93 ? 9 PHE B CA 1 ATOM 4084 C C . PHE B 1 9 ? 61.371 52.995 -3.874 1.00 13.59 ? 9 PHE B C 1 ATOM 4085 O O . PHE B 1 9 ? 62.173 53.411 -4.714 1.00 13.30 ? 9 PHE B O 1 ATOM 4086 C CB . PHE B 1 9 ? 59.647 54.489 -4.882 1.00 14.03 ? 9 PHE B CB 1 ATOM 4087 C CG . PHE B 1 9 ? 58.291 54.584 -5.527 1.00 15.01 ? 9 PHE B CG 1 ATOM 4088 C CD1 . PHE B 1 9 ? 57.378 55.555 -5.124 1.00 15.62 ? 9 PHE B CD1 1 ATOM 4089 C CD2 . PHE B 1 9 ? 57.937 53.722 -6.563 1.00 14.97 ? 9 PHE B CD2 1 ATOM 4090 C CE1 . PHE B 1 9 ? 56.133 55.669 -5.748 1.00 15.44 ? 9 PHE B CE1 1 ATOM 4091 C CE2 . PHE B 1 9 ? 56.696 53.827 -7.191 1.00 13.45 ? 9 PHE B CE2 1 ATOM 4092 C CZ . PHE B 1 9 ? 55.793 54.804 -6.782 1.00 16.10 ? 9 PHE B CZ 1 ATOM 4093 N N . SER B 1 10 ? 61.756 52.347 -2.780 1.00 14.14 ? 10 SER B N 1 ATOM 4094 C CA . SER B 1 10 ? 63.173 52.099 -2.520 1.00 14.76 ? 10 SER B CA 1 ATOM 4095 C C . SER B 1 10 ? 63.806 51.284 -3.646 1.00 15.33 ? 10 SER B C 1 ATOM 4096 O O . SER B 1 10 ? 64.988 51.444 -3.953 1.00 15.10 ? 10 SER B O 1 ATOM 4097 C CB . SER B 1 10 ? 63.354 51.357 -1.191 1.00 14.76 ? 10 SER B CB 1 ATOM 4098 O OG . SER B 1 10 ? 62.924 52.147 -0.096 1.00 15.97 ? 10 SER B OG 1 ATOM 4099 N N . TYR B 1 11 ? 63.008 50.423 -4.271 1.00 13.74 ? 11 TYR B N 1 ATOM 4100 C CA . TYR B 1 11 ? 63.491 49.569 -5.351 1.00 13.94 ? 11 TYR B CA 1 ATOM 4101 C C . TYR B 1 11 ? 63.957 50.320 -6.597 1.00 13.03 ? 11 TYR B C 1 ATOM 4102 O O . TYR B 1 11 ? 64.570 49.730 -7.488 1.00 14.55 ? 11 TYR B O 1 ATOM 4103 C CB . TYR B 1 11 ? 62.405 48.556 -5.738 1.00 12.16 ? 11 TYR B CB 1 ATOM 4104 C CG . TYR B 1 11 ? 61.188 49.162 -6.404 1.00 11.76 ? 11 TYR B CG 1 ATOM 4105 C CD1 . TYR B 1 11 ? 61.217 49.535 -7.747 1.00 11.32 ? 11 TYR B CD1 1 ATOM 4106 C CD2 . TYR B 1 11 ? 60.006 49.360 -5.690 1.00 12.11 ? 11 TYR B CD2 1 ATOM 4107 C CE1 . TYR B 1 11 ? 60.095 50.088 -8.369 1.00 13.05 ? 11 TYR B CE1 1 ATOM 4108 C CE2 . TYR B 1 11 ? 58.878 49.914 -6.300 1.00 11.94 ? 11 TYR B CE2 1 ATOM 4109 C CZ . TYR B 1 11 ? 58.931 50.274 -7.638 1.00 11.93 ? 11 TYR B CZ 1 ATOM 4110 O OH . TYR B 1 11 ? 57.823 50.812 -8.247 1.00 13.19 ? 11 TYR B OH 1 ATOM 4111 N N . LEU B 1 12 ? 63.664 51.614 -6.674 1.00 13.64 ? 12 LEU B N 1 ATOM 4112 C CA . LEU B 1 12 ? 64.079 52.391 -7.834 1.00 14.71 ? 12 LEU B CA 1 ATOM 4113 C C . LEU B 1 12 ? 65.598 52.380 -7.981 1.00 14.51 ? 12 LEU B C 1 ATOM 4114 O O . LEU B 1 12 ? 66.125 52.652 -9.062 1.00 15.12 ? 12 LEU B O 1 ATOM 4115 C CB . LEU B 1 12 ? 63.575 53.833 -7.725 1.00 16.19 ? 12 LEU B CB 1 ATOM 4116 C CG . LEU B 1 12 ? 62.058 54.006 -7.859 1.00 16.12 ? 12 LEU B CG 1 ATOM 4117 C CD1 . LEU B 1 12 ? 61.688 55.478 -7.757 1.00 15.82 ? 12 LEU B CD1 1 ATOM 4118 C CD2 . LEU B 1 12 ? 61.601 53.434 -9.195 1.00 17.01 ? 12 LEU B CD2 1 ATOM 4119 N N . SER B 1 13 ? 66.295 52.057 -6.895 1.00 13.94 ? 13 SER B N 1 ATOM 4120 C CA . SER B 1 13 ? 67.754 52.010 -6.908 1.00 16.20 ? 13 SER B CA 1 ATOM 4121 C C . SER B 1 13 ? 68.267 50.962 -7.890 1.00 15.88 ? 13 SER B C 1 ATOM 4122 O O . SER B 1 13 ? 69.385 51.073 -8.401 1.00 15.52 ? 13 SER B O 1 ATOM 4123 C CB . SER B 1 13 ? 68.293 51.713 -5.504 1.00 14.65 ? 13 SER B CB 1 ATOM 4124 O OG . SER B 1 13 ? 67.931 50.412 -5.075 1.00 17.23 ? 13 SER B OG 1 ATOM 4125 N N . PHE B 1 14 ? 67.460 49.937 -8.151 1.00 15.34 ? 14 PHE B N 1 ATOM 4126 C CA . PHE B 1 14 ? 67.866 48.901 -9.089 1.00 15.07 ? 14 PHE B CA 1 ATOM 4127 C C . PHE B 1 14 ? 66.910 48.745 -10.268 1.00 15.00 ? 14 PHE B C 1 ATOM 4128 O O . PHE B 1 14 ? 66.828 47.682 -10.880 1.00 15.47 ? 14 PHE B O 1 ATOM 4129 C CB . PHE B 1 14 ? 68.080 47.556 -8.368 1.00 15.08 ? 14 PHE B CB 1 ATOM 4130 C CG . PHE B 1 14 ? 66.919 47.103 -7.516 1.00 15.20 ? 14 PHE B CG 1 ATOM 4131 C CD1 . PHE B 1 14 ? 65.766 46.584 -8.096 1.00 15.32 ? 14 PHE B CD1 1 ATOM 4132 C CD2 . PHE B 1 14 ? 67.004 47.147 -6.126 1.00 15.24 ? 14 PHE B CD2 1 ATOM 4133 C CE1 . PHE B 1 14 ? 64.714 46.112 -7.303 1.00 15.55 ? 14 PHE B CE1 1 ATOM 4134 C CE2 . PHE B 1 14 ? 65.959 46.678 -5.321 1.00 16.16 ? 14 PHE B CE2 1 ATOM 4135 C CZ . PHE B 1 14 ? 64.813 46.158 -5.912 1.00 15.63 ? 14 PHE B CZ 1 ATOM 4136 N N . ALA B 1 15 ? 66.194 49.818 -10.588 1.00 15.68 ? 15 ALA B N 1 ATOM 4137 C CA . ALA B 1 15 ? 65.268 49.813 -11.717 1.00 17.84 ? 15 ALA B CA 1 ATOM 4138 C C . ALA B 1 15 ? 65.922 50.591 -12.856 1.00 19.54 ? 15 ALA B C 1 ATOM 4139 O O . ALA B 1 15 ? 66.455 51.680 -12.644 1.00 20.61 ? 15 ALA B O 1 ATOM 4140 C CB . ALA B 1 15 ? 63.950 50.466 -11.325 1.00 16.52 ? 15 ALA B CB 1 ATOM 4141 N N . TYR B 1 16 ? 65.884 50.031 -14.061 1.00 19.84 ? 16 TYR B N 1 ATOM 4142 C CA . TYR B 1 16 ? 66.493 50.684 -15.214 1.00 20.87 ? 16 TYR B CA 1 ATOM 4143 C C . TYR B 1 16 ? 65.586 50.650 -16.429 1.00 20.94 ? 16 TYR B C 1 ATOM 4144 O O . TYR B 1 16 ? 64.751 49.756 -16.571 1.00 20.27 ? 16 TYR B O 1 ATOM 4145 C CB . TYR B 1 16 ? 67.803 49.992 -15.595 1.00 21.96 ? 16 TYR B CB 1 ATOM 4146 C CG . TYR B 1 16 ? 68.790 49.815 -14.468 1.00 24.47 ? 16 TYR B CG 1 ATOM 4147 C CD1 . TYR B 1 16 ? 68.603 48.832 -13.496 1.00 23.80 ? 16 TYR B CD1 1 ATOM 4148 C CD2 . TYR B 1 16 ? 69.920 50.629 -14.375 1.00 25.65 ? 16 TYR B CD2 1 ATOM 4149 C CE1 . TYR B 1 16 ? 69.518 48.661 -12.460 1.00 25.59 ? 16 TYR B CE1 1 ATOM 4150 C CE2 . TYR B 1 16 ? 70.840 50.468 -13.344 1.00 26.53 ? 16 TYR B CE2 1 ATOM 4151 C CZ . TYR B 1 16 ? 70.633 49.484 -12.390 1.00 27.69 ? 16 TYR B CZ 1 ATOM 4152 O OH . TYR B 1 16 ? 71.537 49.328 -11.365 1.00 28.80 ? 16 TYR B OH 1 ATOM 4153 N N . ASP B 1 17 ? 65.752 51.629 -17.310 1.00 21.25 ? 17 ASP B N 1 ATOM 4154 C CA . ASP B 1 17 ? 64.973 51.653 -18.537 1.00 21.54 ? 17 ASP B CA 1 ATOM 4155 C C . ASP B 1 17 ? 65.716 50.669 -19.427 1.00 21.95 ? 17 ASP B C 1 ATOM 4156 O O . ASP B 1 17 ? 66.942 50.586 -19.374 1.00 22.42 ? 17 ASP B O 1 ATOM 4157 C CB . ASP B 1 17 ? 64.972 53.048 -19.167 1.00 21.89 ? 17 ASP B CB 1 ATOM 4158 C CG . ASP B 1 17 ? 64.104 53.122 -20.413 1.00 20.80 ? 17 ASP B CG 1 ATOM 4159 O OD1 . ASP B 1 17 ? 64.491 52.545 -21.452 1.00 21.32 ? 17 ASP B OD1 1 ATOM 4160 O OD2 . ASP B 1 17 ? 63.029 53.751 -20.351 1.00 21.39 ? 17 ASP B OD2 1 ATOM 4161 N N . ALA B 1 18 ? 64.984 49.911 -20.232 1.00 21.40 ? 18 ALA B N 1 ATOM 4162 C CA . ALA B 1 18 ? 65.607 48.919 -21.096 1.00 22.06 ? 18 ALA B CA 1 ATOM 4163 C C . ALA B 1 18 ? 66.736 49.482 -21.958 1.00 22.33 ? 18 ALA B C 1 ATOM 4164 O O . ALA B 1 18 ? 67.669 48.761 -22.311 1.00 22.59 ? 18 ALA B O 1 ATOM 4165 C CB . ALA B 1 18 ? 64.546 48.257 -21.972 1.00 20.95 ? 18 ALA B CB 1 ATOM 4166 N N . THR B 1 19 ? 66.661 50.766 -22.296 1.00 23.37 ? 19 THR B N 1 ATOM 4167 C CA . THR B 1 19 ? 67.700 51.380 -23.119 1.00 24.26 ? 19 THR B CA 1 ATOM 4168 C C . THR B 1 19 ? 69.023 51.475 -22.368 1.00 25.16 ? 19 THR B C 1 ATOM 4169 O O . THR B 1 19 ? 70.081 51.591 -22.979 1.00 26.19 ? 19 THR B O 1 ATOM 4170 C CB . THR B 1 19 ? 67.311 52.797 -23.578 1.00 24.05 ? 19 THR B CB 1 ATOM 4171 O OG1 . THR B 1 19 ? 67.088 53.626 -22.433 1.00 24.80 ? 19 THR B OG1 1 ATOM 4172 C CG2 . THR B 1 19 ? 66.061 52.764 -24.437 1.00 22.38 ? 19 THR B CG2 1 ATOM 4173 N N . ASP B 1 20 ? 68.958 51.424 -21.041 1.00 25.56 ? 20 ASP B N 1 ATOM 4174 C CA . ASP B 1 20 ? 70.159 51.503 -20.219 1.00 26.16 ? 20 ASP B CA 1 ATOM 4175 C C . ASP B 1 20 ? 70.654 50.143 -19.746 1.00 26.01 ? 20 ASP B C 1 ATOM 4176 O O . ASP B 1 20 ? 71.630 50.054 -19.006 1.00 26.92 ? 20 ASP B O 1 ATOM 4177 C CB . ASP B 1 20 ? 69.937 52.432 -19.016 1.00 27.28 ? 20 ASP B CB 1 ATOM 4178 C CG . ASP B 1 20 ? 69.674 53.868 -19.434 1.00 29.31 ? 20 ASP B CG 1 ATOM 4179 O OD1 . ASP B 1 20 ? 70.447 54.387 -20.267 1.00 30.40 ? 20 ASP B OD1 1 ATOM 4180 O OD2 . ASP B 1 20 ? 68.704 54.476 -18.935 1.00 29.21 ? 20 ASP B OD2 1 ATOM 4181 N N . LEU B 1 21 ? 69.977 49.086 -20.181 1.00 25.13 ? 21 LEU B N 1 ATOM 4182 C CA . LEU B 1 21 ? 70.375 47.732 -19.825 1.00 24.33 ? 21 LEU B CA 1 ATOM 4183 C C . LEU B 1 21 ? 71.369 47.242 -20.859 1.00 24.35 ? 21 LEU B C 1 ATOM 4184 O O . LEU B 1 21 ? 71.381 47.723 -21.990 1.00 25.13 ? 21 LEU B O 1 ATOM 4185 C CB . LEU B 1 21 ? 69.159 46.797 -19.787 1.00 24.13 ? 21 LEU B CB 1 ATOM 4186 C CG . LEU B 1 21 ? 68.220 46.916 -18.583 1.00 24.27 ? 21 LEU B CG 1 ATOM 4187 C CD1 . LEU B 1 21 ? 67.098 45.902 -18.719 1.00 23.74 ? 21 LEU B CD1 1 ATOM 4188 C CD2 . LEU B 1 21 ? 68.996 46.668 -17.296 1.00 23.55 ? 21 LEU B CD2 1 ATOM 4189 N N . GLU B 1 22 ? 72.199 46.281 -20.472 1.00 25.17 ? 22 GLU B N 1 ATOM 4190 C CA . GLU B 1 22 ? 73.193 45.736 -21.385 1.00 25.44 ? 22 GLU B CA 1 ATOM 4191 C C . GLU B 1 22 ? 72.509 45.041 -22.571 1.00 25.96 ? 22 GLU B C 1 ATOM 4192 O O . GLU B 1 22 ? 71.385 44.548 -22.445 1.00 25.60 ? 22 GLU B O 1 ATOM 4193 C CB . GLU B 1 22 ? 74.110 44.750 -20.644 1.00 25.72 ? 22 GLU B CB 1 ATOM 4194 C CG . GLU B 1 22 ? 73.451 43.454 -20.169 1.00 25.19 ? 22 GLU B CG 1 ATOM 4195 C CD . GLU B 1 22 ? 72.459 43.650 -19.029 1.00 25.37 ? 22 GLU B CD 1 ATOM 4196 O OE1 . GLU B 1 22 ? 72.645 44.582 -18.219 1.00 23.28 ? 22 GLU B OE1 1 ATOM 4197 O OE2 . GLU B 1 22 ? 71.496 42.856 -18.932 1.00 22.33 ? 22 GLU B OE2 1 ATOM 4198 N N . LEU B 1 23 ? 73.174 45.023 -23.726 1.00 25.82 ? 23 LEU B N 1 ATOM 4199 C CA . LEU B 1 23 ? 72.617 44.380 -24.919 1.00 26.87 ? 23 LEU B CA 1 ATOM 4200 C C . LEU B 1 23 ? 72.583 42.869 -24.758 1.00 26.83 ? 23 LEU B C 1 ATOM 4201 O O . LEU B 1 23 ? 71.739 42.190 -25.345 1.00 27.59 ? 23 LEU B O 1 ATOM 4202 C CB . LEU B 1 23 ? 73.438 44.719 -26.169 1.00 28.43 ? 23 LEU B CB 1 ATOM 4203 C CG . LEU B 1 23 ? 73.539 46.167 -26.664 1.00 29.68 ? 23 LEU B CG 1 ATOM 4204 C CD1 . LEU B 1 23 ? 74.250 46.156 -28.016 1.00 30.38 ? 23 LEU B CD1 1 ATOM 4205 C CD2 . LEU B 1 23 ? 72.153 46.807 -26.787 1.00 28.17 ? 23 LEU B CD2 1 ATOM 4206 N N . GLU B 1 24 ? 73.523 42.339 -23.983 1.00 26.63 ? 24 GLU B N 1 ATOM 4207 C CA . GLU B 1 24 ? 73.588 40.901 -23.737 1.00 26.88 ? 24 GLU B CA 1 ATOM 4208 C C . GLU B 1 24 ? 73.951 40.655 -22.278 1.00 25.71 ? 24 GLU B C 1 ATOM 4209 O O . GLU B 1 24 ? 75.047 40.981 -21.835 1.00 25.28 ? 24 GLU B O 1 ATOM 4210 C CB . GLU B 1 24 ? 74.632 40.233 -24.637 1.00 29.31 ? 24 GLU B CB 1 ATOM 4211 C CG . GLU B 1 24 ? 74.611 38.713 -24.542 1.00 34.09 ? 24 GLU B CG 1 ATOM 4212 C CD . GLU B 1 24 ? 75.455 38.039 -25.605 1.00 36.68 ? 24 GLU B CD 1 ATOM 4213 O OE1 . GLU B 1 24 ? 75.476 38.542 -26.750 1.00 39.07 ? 24 GLU B OE1 1 ATOM 4214 O OE2 . GLU B 1 24 ? 76.081 36.998 -25.295 1.00 38.20 ? 24 GLU B OE2 1 ATOM 4215 N N . GLY B 1 25 ? 73.024 40.067 -21.534 1.00 24.16 ? 25 GLY B N 1 ATOM 4216 C CA . GLY B 1 25 ? 73.260 39.816 -20.125 1.00 22.52 ? 25 GLY B CA 1 ATOM 4217 C C . GLY B 1 25 ? 73.063 38.384 -19.703 1.00 19.94 ? 25 GLY B C 1 ATOM 4218 O O . GLY B 1 25 ? 72.409 37.612 -20.394 1.00 19.65 ? 25 GLY B O 1 ATOM 4219 N N . SER B 1 26 ? 73.631 38.041 -18.553 1.00 18.33 ? 26 SER B N 1 ATOM 4220 C CA . SER B 1 26 ? 73.554 36.695 -18.002 1.00 16.07 ? 26 SER B CA 1 ATOM 4221 C C . SER B 1 26 ? 73.032 36.766 -16.570 1.00 15.73 ? 26 SER B C 1 ATOM 4222 O O . SER B 1 26 ? 73.519 37.561 -15.771 1.00 16.24 ? 26 SER B O 1 ATOM 4223 C CB . SER B 1 26 ? 74.949 36.067 -18.004 1.00 17.65 ? 26 SER B CB 1 ATOM 4224 O OG . SER B 1 26 ? 74.933 34.768 -17.451 1.00 16.62 ? 26 SER B OG 1 ATOM 4225 N N . TYR B 1 27 ? 72.042 35.938 -16.248 1.00 14.30 ? 27 TYR B N 1 ATOM 4226 C CA . TYR B 1 27 ? 71.451 35.910 -14.908 1.00 12.98 ? 27 TYR B CA 1 ATOM 4227 C C . TYR B 1 27 ? 71.091 34.483 -14.522 1.00 12.55 ? 27 TYR B C 1 ATOM 4228 O O . TYR B 1 27 ? 71.177 33.577 -15.342 1.00 12.92 ? 27 TYR B O 1 ATOM 4229 C CB . TYR B 1 27 ? 70.168 36.755 -14.863 1.00 12.35 ? 27 TYR B CB 1 ATOM 4230 C CG . TYR B 1 27 ? 70.340 38.194 -15.286 1.00 14.02 ? 27 TYR B CG 1 ATOM 4231 C CD1 . TYR B 1 27 ? 70.404 38.545 -16.636 1.00 12.64 ? 27 TYR B CD1 1 ATOM 4232 C CD2 . TYR B 1 27 ? 70.472 39.203 -14.336 1.00 12.15 ? 27 TYR B CD2 1 ATOM 4233 C CE1 . TYR B 1 27 ? 70.599 39.868 -17.024 1.00 12.74 ? 27 TYR B CE1 1 ATOM 4234 C CE2 . TYR B 1 27 ? 70.668 40.525 -14.712 1.00 13.64 ? 27 TYR B CE2 1 ATOM 4235 C CZ . TYR B 1 27 ? 70.732 40.851 -16.058 1.00 13.36 ? 27 TYR B CZ 1 ATOM 4236 O OH . TYR B 1 27 ? 70.939 42.159 -16.431 1.00 16.33 ? 27 TYR B OH 1 ATOM 4237 N N . ASP B 1 28 ? 70.685 34.285 -13.271 1.00 11.94 ? 28 ASP B N 1 ATOM 4238 C CA . ASP B 1 28 ? 70.268 32.962 -12.822 1.00 11.49 ? 28 ASP B CA 1 ATOM 4239 C C . ASP B 1 28 ? 68.805 32.764 -13.227 1.00 11.41 ? 28 ASP B C 1 ATOM 4240 O O . ASP B 1 28 ? 68.412 31.683 -13.670 1.00 11.25 ? 28 ASP B O 1 ATOM 4241 C CB . ASP B 1 28 ? 70.405 32.829 -11.306 1.00 13.27 ? 28 ASP B CB 1 ATOM 4242 C CG . ASP B 1 28 ? 71.849 32.709 -10.861 1.00 14.05 ? 28 ASP B CG 1 ATOM 4243 O OD1 . ASP B 1 28 ? 72.527 31.761 -11.311 1.00 14.36 ? 28 ASP B OD1 1 ATOM 4244 O OD2 . ASP B 1 28 ? 72.307 33.556 -10.065 1.00 14.08 ? 28 ASP B OD2 1 ATOM 4245 N N . TYR B 1 29 ? 68.003 33.814 -13.068 1.00 10.25 ? 29 TYR B N 1 ATOM 4246 C CA . TYR B 1 29 ? 66.590 33.755 -13.433 1.00 9.69 ? 29 TYR B CA 1 ATOM 4247 C C . TYR B 1 29 ? 66.155 35.016 -14.159 1.00 9.97 ? 29 TYR B C 1 ATOM 4248 O O . TYR B 1 29 ? 66.570 36.123 -13.816 1.00 10.80 ? 29 TYR B O 1 ATOM 4249 C CB . TYR B 1 29 ? 65.698 33.573 -12.195 1.00 10.83 ? 29 TYR B CB 1 ATOM 4250 C CG . TYR B 1 29 ? 65.937 32.283 -11.455 1.00 10.49 ? 29 TYR B CG 1 ATOM 4251 C CD1 . TYR B 1 29 ? 66.910 32.201 -10.460 1.00 10.30 ? 29 TYR B CD1 1 ATOM 4252 C CD2 . TYR B 1 29 ? 65.240 31.126 -11.794 1.00 11.33 ? 29 TYR B CD2 1 ATOM 4253 C CE1 . TYR B 1 29 ? 67.188 30.998 -9.828 1.00 11.69 ? 29 TYR B CE1 1 ATOM 4254 C CE2 . TYR B 1 29 ? 65.510 29.912 -11.165 1.00 11.02 ? 29 TYR B CE2 1 ATOM 4255 C CZ . TYR B 1 29 ? 66.490 29.857 -10.184 1.00 11.01 ? 29 TYR B CZ 1 ATOM 4256 O OH . TYR B 1 29 ? 66.786 28.661 -9.575 1.00 14.07 ? 29 TYR B OH 1 ATOM 4257 N N . VAL B 1 30 ? 65.330 34.833 -15.182 1.00 9.91 ? 30 VAL B N 1 ATOM 4258 C CA . VAL B 1 30 ? 64.793 35.947 -15.948 1.00 10.66 ? 30 VAL B CA 1 ATOM 4259 C C . VAL B 1 30 ? 63.282 35.814 -15.845 1.00 10.78 ? 30 VAL B C 1 ATOM 4260 O O . VAL B 1 30 ? 62.719 34.775 -16.197 1.00 11.57 ? 30 VAL B O 1 ATOM 4261 C CB . VAL B 1 30 ? 65.218 35.888 -17.433 1.00 10.55 ? 30 VAL B CB 1 ATOM 4262 C CG1 . VAL B 1 30 ? 64.496 36.975 -18.224 1.00 12.36 ? 30 VAL B CG1 1 ATOM 4263 C CG2 . VAL B 1 30 ? 66.727 36.074 -17.547 1.00 12.13 ? 30 VAL B CG2 1 ATOM 4264 N N . ILE B 1 31 ? 62.633 36.850 -15.326 1.00 10.83 ? 31 ILE B N 1 ATOM 4265 C CA . ILE B 1 31 ? 61.184 36.837 -15.166 1.00 11.00 ? 31 ILE B CA 1 ATOM 4266 C C . ILE B 1 31 ? 60.546 37.798 -16.160 1.00 10.44 ? 31 ILE B C 1 ATOM 4267 O O . ILE B 1 31 ? 60.882 38.983 -16.198 1.00 11.13 ? 31 ILE B O 1 ATOM 4268 C CB . ILE B 1 31 ? 60.772 37.246 -13.723 1.00 12.93 ? 31 ILE B CB 1 ATOM 4269 C CG1 . ILE B 1 31 ? 61.269 36.205 -12.712 1.00 15.43 ? 31 ILE B CG1 1 ATOM 4270 C CG2 . ILE B 1 31 ? 59.258 37.359 -13.620 1.00 12.68 ? 31 ILE B CG2 1 ATOM 4271 C CD1 . ILE B 1 31 ? 62.767 36.136 -12.566 1.00 21.29 ? 31 ILE B CD1 1 ATOM 4272 N N . VAL B 1 32 ? 59.632 37.278 -16.973 1.00 9.06 ? 32 VAL B N 1 ATOM 4273 C CA . VAL B 1 32 ? 58.945 38.094 -17.967 1.00 9.01 ? 32 VAL B CA 1 ATOM 4274 C C . VAL B 1 32 ? 57.643 38.625 -17.391 1.00 8.60 ? 32 VAL B C 1 ATOM 4275 O O . VAL B 1 32 ? 56.717 37.858 -17.117 1.00 9.73 ? 32 VAL B O 1 ATOM 4276 C CB . VAL B 1 32 ? 58.631 37.282 -19.243 1.00 8.07 ? 32 VAL B CB 1 ATOM 4277 C CG1 . VAL B 1 32 ? 57.881 38.149 -20.244 1.00 11.09 ? 32 VAL B CG1 1 ATOM 4278 C CG2 . VAL B 1 32 ? 59.923 36.768 -19.859 1.00 11.05 ? 32 VAL B CG2 1 ATOM 4279 N N . GLY B 1 33 ? 57.584 39.943 -17.214 1.00 8.75 ? 33 GLY B N 1 ATOM 4280 C CA . GLY B 1 33 ? 56.398 40.572 -16.663 1.00 9.80 ? 33 GLY B CA 1 ATOM 4281 C C . GLY B 1 33 ? 56.552 40.893 -15.187 1.00 8.69 ? 33 GLY B C 1 ATOM 4282 O O . GLY B 1 33 ? 56.538 39.992 -14.351 1.00 8.69 ? 33 GLY B O 1 ATOM 4283 N N . GLY B 1 34 ? 56.707 42.174 -14.865 1.00 7.67 ? 34 GLY B N 1 ATOM 4284 C CA . GLY B 1 34 ? 56.852 42.578 -13.477 1.00 7.78 ? 34 GLY B CA 1 ATOM 4285 C C . GLY B 1 34 ? 55.483 42.899 -12.913 1.00 9.11 ? 34 GLY B C 1 ATOM 4286 O O . GLY B 1 34 ? 55.211 44.028 -12.494 1.00 9.42 ? 34 GLY B O 1 ATOM 4287 N N . GLY B 1 35 ? 54.617 41.892 -12.904 1.00 8.16 ? 35 GLY B N 1 ATOM 4288 C CA . GLY B 1 35 ? 53.264 42.089 -12.425 1.00 8.25 ? 35 GLY B CA 1 ATOM 4289 C C . GLY B 1 35 ? 52.959 41.589 -11.030 1.00 9.05 ? 35 GLY B C 1 ATOM 4290 O O . GLY B 1 35 ? 53.838 41.494 -10.169 1.00 8.79 ? 35 GLY B O 1 ATOM 4291 N N . THR B 1 36 ? 51.689 41.263 -10.820 1.00 7.27 ? 36 THR B N 1 ATOM 4292 C CA . THR B 1 36 ? 51.195 40.787 -9.536 1.00 7.62 ? 36 THR B CA 1 ATOM 4293 C C . THR B 1 36 ? 51.971 39.579 -9.016 1.00 7.83 ? 36 THR B C 1 ATOM 4294 O O . THR B 1 36 ? 52.443 39.593 -7.879 1.00 8.56 ? 36 THR B O 1 ATOM 4295 C CB . THR B 1 36 ? 49.699 40.466 -9.644 1.00 6.21 ? 36 THR B CB 1 ATOM 4296 O OG1 . THR B 1 36 ? 49.027 41.600 -10.210 1.00 7.92 ? 36 THR B OG1 1 ATOM 4297 C CG2 . THR B 1 36 ? 49.100 40.181 -8.269 1.00 8.34 ? 36 THR B CG2 1 ATOM 4298 N N . SER B 1 37 ? 52.110 38.543 -9.840 1.00 8.17 ? 37 SER B N 1 ATOM 4299 C CA . SER B 1 37 ? 52.866 37.357 -9.434 1.00 8.05 ? 37 SER B CA 1 ATOM 4300 C C . SER B 1 37 ? 54.361 37.557 -9.682 1.00 8.18 ? 37 SER B C 1 ATOM 4301 O O . SER B 1 37 ? 55.198 37.127 -8.887 1.00 8.82 ? 37 SER B O 1 ATOM 4302 C CB . SER B 1 37 ? 52.403 36.116 -10.209 1.00 8.24 ? 37 SER B CB 1 ATOM 4303 O OG . SER B 1 37 ? 51.103 35.703 -9.824 1.00 7.97 ? 37 SER B OG 1 ATOM 4304 N N . GLY B 1 38 ? 54.684 38.213 -10.791 1.00 8.14 ? 38 GLY B N 1 ATOM 4305 C CA . GLY B 1 38 ? 56.072 38.441 -11.159 1.00 7.61 ? 38 GLY B CA 1 ATOM 4306 C C . GLY B 1 38 ? 56.963 39.138 -10.147 1.00 8.22 ? 38 GLY B C 1 ATOM 4307 O O . GLY B 1 38 ? 58.094 38.714 -9.927 1.00 8.64 ? 38 GLY B O 1 ATOM 4308 N N . CYS B 1 39 ? 56.471 40.204 -9.529 1.00 8.63 ? 39 CYS B N 1 ATOM 4309 C CA . CYS B 1 39 ? 57.284 40.935 -8.564 1.00 9.40 ? 39 CYS B CA 1 ATOM 4310 C C . CYS B 1 39 ? 57.661 40.119 -7.326 1.00 9.62 ? 39 CYS B C 1 ATOM 4311 O O . CYS B 1 39 ? 58.838 40.033 -6.978 1.00 8.47 ? 39 CYS B O 1 ATOM 4312 C CB . CYS B 1 39 ? 56.586 42.241 -8.176 1.00 10.48 ? 39 CYS B CB 1 ATOM 4313 S SG . CYS B 1 39 ? 56.575 43.459 -9.523 1.00 10.20 ? 39 CYS B SG 1 ATOM 4314 N N . PRO B 1 40 ? 56.680 39.509 -6.641 1.00 8.95 ? 40 PRO B N 1 ATOM 4315 C CA . PRO B 1 40 ? 57.063 38.724 -5.461 1.00 8.76 ? 40 PRO B CA 1 ATOM 4316 C C . PRO B 1 40 ? 57.932 37.517 -5.820 1.00 8.77 ? 40 PRO B C 1 ATOM 4317 O O . PRO B 1 40 ? 58.780 37.098 -5.030 1.00 9.13 ? 40 PRO B O 1 ATOM 4318 C CB . PRO B 1 40 ? 55.718 38.331 -4.842 1.00 10.04 ? 40 PRO B CB 1 ATOM 4319 C CG . PRO B 1 40 ? 54.761 38.382 -6.015 1.00 9.87 ? 40 PRO B CG 1 ATOM 4320 C CD . PRO B 1 40 ? 55.215 39.606 -6.762 1.00 9.55 ? 40 PRO B CD 1 ATOM 4321 N N . LEU B 1 41 ? 57.722 36.962 -7.012 1.00 9.36 ? 41 LEU B N 1 ATOM 4322 C CA . LEU B 1 41 ? 58.521 35.824 -7.463 1.00 8.58 ? 41 LEU B CA 1 ATOM 4323 C C . LEU B 1 41 ? 59.968 36.287 -7.615 1.00 9.49 ? 41 LEU B C 1 ATOM 4324 O O . LEU B 1 41 ? 60.899 35.665 -7.088 1.00 9.02 ? 41 LEU B O 1 ATOM 4325 C CB . LEU B 1 41 ? 58.006 35.304 -8.811 1.00 9.72 ? 41 LEU B CB 1 ATOM 4326 C CG . LEU B 1 41 ? 58.896 34.277 -9.525 1.00 10.52 ? 41 LEU B CG 1 ATOM 4327 C CD1 . LEU B 1 41 ? 59.074 33.035 -8.659 1.00 10.76 ? 41 LEU B CD1 1 ATOM 4328 C CD2 . LEU B 1 41 ? 58.272 33.912 -10.866 1.00 11.60 ? 41 LEU B CD2 1 ATOM 4329 N N . ALA B 1 42 ? 60.146 37.390 -8.332 1.00 9.14 ? 42 ALA B N 1 ATOM 4330 C CA . ALA B 1 42 ? 61.472 37.952 -8.560 1.00 9.19 ? 42 ALA B CA 1 ATOM 4331 C C . ALA B 1 42 ? 62.189 38.274 -7.250 1.00 9.32 ? 42 ALA B C 1 ATOM 4332 O O . ALA B 1 42 ? 63.361 37.933 -7.075 1.00 9.97 ? 42 ALA B O 1 ATOM 4333 C CB . ALA B 1 42 ? 61.356 39.203 -9.409 1.00 10.12 ? 42 ALA B CB 1 ATOM 4334 N N . ALA B 1 43 ? 61.489 38.939 -6.335 1.00 8.97 ? 43 ALA B N 1 ATOM 4335 C CA . ALA B 1 43 ? 62.073 39.309 -5.046 1.00 9.07 ? 43 ALA B CA 1 ATOM 4336 C C . ALA B 1 43 ? 62.538 38.085 -4.261 1.00 9.22 ? 43 ALA B C 1 ATOM 4337 O O . ALA B 1 43 ? 63.630 38.078 -3.684 1.00 11.06 ? 43 ALA B O 1 ATOM 4338 C CB . ALA B 1 43 ? 61.059 40.100 -4.227 1.00 8.86 ? 43 ALA B CB 1 ATOM 4339 N N . THR B 1 44 ? 61.708 37.049 -4.243 1.00 8.37 ? 44 THR B N 1 ATOM 4340 C CA . THR B 1 44 ? 62.028 35.826 -3.526 1.00 8.67 ? 44 THR B CA 1 ATOM 4341 C C . THR B 1 44 ? 63.280 35.156 -4.079 1.00 10.57 ? 44 THR B C 1 ATOM 4342 O O . THR B 1 44 ? 64.201 34.823 -3.332 1.00 11.12 ? 44 THR B O 1 ATOM 4343 C CB . THR B 1 44 ? 60.847 34.850 -3.590 1.00 9.81 ? 44 THR B CB 1 ATOM 4344 O OG1 . THR B 1 44 ? 59.728 35.437 -2.916 1.00 9.50 ? 44 THR B OG1 1 ATOM 4345 C CG2 . THR B 1 44 ? 61.196 33.521 -2.929 1.00 10.65 ? 44 THR B CG2 1 ATOM 4346 N N . LEU B 1 45 ? 63.316 34.962 -5.391 1.00 10.69 ? 45 LEU B N 1 ATOM 4347 C CA . LEU B 1 45 ? 64.469 34.333 -6.016 1.00 11.03 ? 45 LEU B CA 1 ATOM 4348 C C . LEU B 1 45 ? 65.739 35.153 -5.800 1.00 12.55 ? 45 LEU B C 1 ATOM 4349 O O . LEU B 1 45 ? 66.820 34.584 -5.647 1.00 11.93 ? 45 LEU B O 1 ATOM 4350 C CB . LEU B 1 45 ? 64.216 34.140 -7.515 1.00 10.84 ? 45 LEU B CB 1 ATOM 4351 C CG . LEU B 1 45 ? 63.131 33.117 -7.870 1.00 9.08 ? 45 LEU B CG 1 ATOM 4352 C CD1 . LEU B 1 45 ? 62.825 33.177 -9.358 1.00 11.17 ? 45 LEU B CD1 1 ATOM 4353 C CD2 . LEU B 1 45 ? 63.591 31.723 -7.472 1.00 10.99 ? 45 LEU B CD2 1 ATOM 4354 N N . SER B 1 46 ? 65.604 36.479 -5.769 1.00 12.04 ? 46 SER B N 1 ATOM 4355 C CA . SER B 1 46 ? 66.757 37.361 -5.588 1.00 12.10 ? 46 SER B CA 1 ATOM 4356 C C . SER B 1 46 ? 67.400 37.222 -4.212 1.00 12.52 ? 46 SER B C 1 ATOM 4357 O O . SER B 1 46 ? 68.477 37.764 -3.972 1.00 13.79 ? 46 SER B O 1 ATOM 4358 C CB . SER B 1 46 ? 66.365 38.826 -5.826 1.00 10.85 ? 46 SER B CB 1 ATOM 4359 O OG . SER B 1 46 ? 65.683 39.376 -4.711 1.00 11.43 ? 46 SER B OG 1 ATOM 4360 N N . GLU B 1 47 ? 66.742 36.504 -3.308 1.00 12.88 ? 47 GLU B N 1 ATOM 4361 C CA . GLU B 1 47 ? 67.295 36.305 -1.973 1.00 13.53 ? 47 GLU B CA 1 ATOM 4362 C C . GLU B 1 47 ? 68.608 35.530 -2.054 1.00 14.28 ? 47 GLU B C 1 ATOM 4363 O O . GLU B 1 47 ? 69.489 35.689 -1.205 1.00 13.61 ? 47 GLU B O 1 ATOM 4364 C CB . GLU B 1 47 ? 66.292 35.559 -1.087 1.00 14.92 ? 47 GLU B CB 1 ATOM 4365 C CG . GLU B 1 47 ? 65.177 36.451 -0.552 1.00 17.42 ? 47 GLU B CG 1 ATOM 4366 C CD . GLU B 1 47 ? 64.114 35.681 0.210 1.00 18.81 ? 47 GLU B CD 1 ATOM 4367 O OE1 . GLU B 1 47 ? 64.461 34.691 0.886 1.00 22.05 ? 47 GLU B OE1 1 ATOM 4368 O OE2 . GLU B 1 47 ? 62.930 36.077 0.145 1.00 18.28 ? 47 GLU B OE2 1 ATOM 4369 N N . LYS B 1 48 ? 68.745 34.704 -3.086 1.00 14.05 ? 48 LYS B N 1 ATOM 4370 C CA . LYS B 1 48 ? 69.953 33.906 -3.257 1.00 15.06 ? 48 LYS B CA 1 ATOM 4371 C C . LYS B 1 48 ? 70.575 33.999 -4.644 1.00 15.54 ? 48 LYS B C 1 ATOM 4372 O O . LYS B 1 48 ? 71.781 33.786 -4.801 1.00 15.88 ? 48 LYS B O 1 ATOM 4373 C CB . LYS B 1 48 ? 69.658 32.434 -2.955 1.00 16.37 ? 48 LYS B CB 1 ATOM 4374 C CG . LYS B 1 48 ? 69.287 32.146 -1.510 1.00 21.29 ? 48 LYS B CG 1 ATOM 4375 C CD . LYS B 1 48 ? 69.146 30.651 -1.277 1.00 23.62 ? 48 LYS B CD 1 ATOM 4376 C CE . LYS B 1 48 ? 68.843 30.337 0.181 1.00 25.74 ? 48 LYS B CE 1 ATOM 4377 N NZ . LYS B 1 48 ? 68.756 28.866 0.415 1.00 26.70 ? 48 LYS B NZ 1 ATOM 4378 N N . TYR B 1 49 ? 69.769 34.328 -5.647 1.00 14.87 ? 49 TYR B N 1 ATOM 4379 C CA . TYR B 1 49 ? 70.283 34.382 -7.008 1.00 13.26 ? 49 TYR B CA 1 ATOM 4380 C C . TYR B 1 49 ? 70.144 35.705 -7.747 1.00 13.21 ? 49 TYR B C 1 ATOM 4381 O O . TYR B 1 49 ? 69.432 36.610 -7.312 1.00 11.71 ? 49 TYR B O 1 ATOM 4382 C CB . TYR B 1 49 ? 69.643 33.259 -7.829 1.00 14.11 ? 49 TYR B CB 1 ATOM 4383 C CG . TYR B 1 49 ? 69.959 31.880 -7.296 1.00 15.77 ? 49 TYR B CG 1 ATOM 4384 C CD1 . TYR B 1 49 ? 69.034 31.173 -6.525 1.00 15.27 ? 49 TYR B CD1 1 ATOM 4385 C CD2 . TYR B 1 49 ? 71.202 31.295 -7.532 1.00 16.59 ? 49 TYR B CD2 1 ATOM 4386 C CE1 . TYR B 1 49 ? 69.344 29.917 -6.002 1.00 18.94 ? 49 TYR B CE1 1 ATOM 4387 C CE2 . TYR B 1 49 ? 71.521 30.045 -7.014 1.00 18.69 ? 49 TYR B CE2 1 ATOM 4388 C CZ . TYR B 1 49 ? 70.592 29.362 -6.250 1.00 19.27 ? 49 TYR B CZ 1 ATOM 4389 O OH . TYR B 1 49 ? 70.920 28.130 -5.728 1.00 22.14 ? 49 TYR B OH 1 ATOM 4390 N N . LYS B 1 50 ? 70.852 35.807 -8.869 1.00 12.32 ? 50 LYS B N 1 ATOM 4391 C CA . LYS B 1 50 ? 70.827 37.003 -9.700 1.00 12.47 ? 50 LYS B CA 1 ATOM 4392 C C . LYS B 1 50 ? 69.586 36.938 -10.577 1.00 12.81 ? 50 LYS B C 1 ATOM 4393 O O . LYS B 1 50 ? 69.438 36.034 -11.401 1.00 13.52 ? 50 LYS B O 1 ATOM 4394 C CB . LYS B 1 50 ? 72.092 37.070 -10.555 1.00 11.43 ? 50 LYS B CB 1 ATOM 4395 C CG . LYS B 1 50 ? 73.372 37.151 -9.731 1.00 11.89 ? 50 LYS B CG 1 ATOM 4396 C CD . LYS B 1 50 ? 73.434 38.456 -8.951 1.00 13.46 ? 50 LYS B CD 1 ATOM 4397 C CE . LYS B 1 50 ? 74.688 38.539 -8.094 1.00 14.27 ? 50 LYS B CE 1 ATOM 4398 N NZ . LYS B 1 50 ? 74.787 39.858 -7.412 1.00 15.44 ? 50 LYS B NZ 1 ATOM 4399 N N . VAL B 1 51 ? 68.703 37.912 -10.392 1.00 10.80 ? 51 VAL B N 1 ATOM 4400 C CA . VAL B 1 51 ? 67.438 37.961 -11.112 1.00 11.61 ? 51 VAL B CA 1 ATOM 4401 C C . VAL B 1 51 ? 67.235 39.222 -11.938 1.00 11.96 ? 51 VAL B C 1 ATOM 4402 O O . VAL B 1 51 ? 67.617 40.318 -11.526 1.00 11.36 ? 51 VAL B O 1 ATOM 4403 C CB . VAL B 1 51 ? 66.259 37.859 -10.107 1.00 11.17 ? 51 VAL B CB 1 ATOM 4404 C CG1 . VAL B 1 51 ? 64.928 37.887 -10.842 1.00 9.31 ? 51 VAL B CG1 1 ATOM 4405 C CG2 . VAL B 1 51 ? 66.395 36.596 -9.272 1.00 10.77 ? 51 VAL B CG2 1 ATOM 4406 N N . LEU B 1 52 ? 66.629 39.049 -13.109 1.00 12.26 ? 52 LEU B N 1 ATOM 4407 C CA . LEU B 1 52 ? 66.304 40.160 -13.990 1.00 12.93 ? 52 LEU B CA 1 ATOM 4408 C C . LEU B 1 52 ? 64.808 40.090 -14.273 1.00 12.20 ? 52 LEU B C 1 ATOM 4409 O O . LEU B 1 52 ? 64.295 39.049 -14.688 1.00 12.06 ? 52 LEU B O 1 ATOM 4410 C CB . LEU B 1 52 ? 67.066 40.076 -15.318 1.00 11.99 ? 52 LEU B CB 1 ATOM 4411 C CG . LEU B 1 52 ? 66.604 41.106 -16.359 1.00 13.56 ? 52 LEU B CG 1 ATOM 4412 C CD1 . LEU B 1 52 ? 66.900 42.516 -15.862 1.00 14.79 ? 52 LEU B CD1 1 ATOM 4413 C CD2 . LEU B 1 52 ? 67.302 40.857 -17.684 1.00 14.50 ? 52 LEU B CD2 1 ATOM 4414 N N . VAL B 1 53 ? 64.111 41.191 -14.021 1.00 12.57 ? 53 VAL B N 1 ATOM 4415 C CA . VAL B 1 53 ? 62.679 41.274 -14.274 1.00 12.60 ? 53 VAL B CA 1 ATOM 4416 C C . VAL B 1 53 ? 62.502 42.227 -15.441 1.00 13.50 ? 53 VAL B C 1 ATOM 4417 O O . VAL B 1 53 ? 63.041 43.331 -15.426 1.00 15.05 ? 53 VAL B O 1 ATOM 4418 C CB . VAL B 1 53 ? 61.917 41.846 -13.068 1.00 16.15 ? 53 VAL B CB 1 ATOM 4419 C CG1 . VAL B 1 53 ? 60.429 41.895 -13.372 1.00 16.15 ? 53 VAL B CG1 1 ATOM 4420 C CG2 . VAL B 1 53 ? 62.184 41.007 -11.849 1.00 17.76 ? 53 VAL B CG2 1 ATOM 4421 N N . LEU B 1 54 ? 61.752 41.798 -16.449 1.00 10.77 ? 54 LEU B N 1 ATOM 4422 C CA . LEU B 1 54 ? 61.516 42.618 -17.634 1.00 10.98 ? 54 LEU B CA 1 ATOM 4423 C C . LEU B 1 54 ? 60.043 42.989 -17.743 1.00 10.81 ? 54 LEU B C 1 ATOM 4424 O O . LEU B 1 54 ? 59.187 42.122 -17.917 1.00 11.34 ? 54 LEU B O 1 ATOM 4425 C CB . LEU B 1 54 ? 61.968 41.859 -18.882 1.00 11.54 ? 54 LEU B CB 1 ATOM 4426 C CG . LEU B 1 54 ? 63.468 41.552 -18.898 1.00 12.45 ? 54 LEU B CG 1 ATOM 4427 C CD1 . LEU B 1 54 ? 63.793 40.556 -20.001 1.00 12.28 ? 54 LEU B CD1 1 ATOM 4428 C CD2 . LEU B 1 54 ? 64.242 42.850 -19.086 1.00 13.94 ? 54 LEU B CD2 1 ATOM 4429 N N . GLU B 1 55 ? 59.761 44.286 -17.647 1.00 9.74 ? 55 GLU B N 1 ATOM 4430 C CA . GLU B 1 55 ? 58.394 44.799 -17.714 1.00 10.55 ? 55 GLU B CA 1 ATOM 4431 C C . GLU B 1 55 ? 58.213 45.755 -18.889 1.00 10.58 ? 55 GLU B C 1 ATOM 4432 O O . GLU B 1 55 ? 58.988 46.690 -19.062 1.00 11.30 ? 55 GLU B O 1 ATOM 4433 C CB . GLU B 1 55 ? 58.057 45.512 -16.400 1.00 10.82 ? 55 GLU B CB 1 ATOM 4434 C CG . GLU B 1 55 ? 56.772 46.319 -16.413 1.00 11.12 ? 55 GLU B CG 1 ATOM 4435 C CD . GLU B 1 55 ? 55.565 45.486 -16.769 1.00 9.94 ? 55 GLU B CD 1 ATOM 4436 O OE1 . GLU B 1 55 ? 55.448 44.357 -16.247 1.00 10.79 ? 55 GLU B OE1 1 ATOM 4437 O OE2 . GLU B 1 55 ? 54.730 45.965 -17.563 1.00 10.90 ? 55 GLU B OE2 1 ATOM 4438 N N . ARG B 1 56 ? 57.174 45.527 -19.685 1.00 8.78 ? 56 ARG B N 1 ATOM 4439 C CA . ARG B 1 56 ? 56.914 46.361 -20.854 1.00 10.63 ? 56 ARG B CA 1 ATOM 4440 C C . ARG B 1 56 ? 56.453 47.778 -20.521 1.00 10.43 ? 56 ARG B C 1 ATOM 4441 O O . ARG B 1 56 ? 56.709 48.709 -21.284 1.00 11.44 ? 56 ARG B O 1 ATOM 4442 C CB . ARG B 1 56 ? 55.868 45.691 -21.747 1.00 9.74 ? 56 ARG B CB 1 ATOM 4443 C CG . ARG B 1 56 ? 54.523 45.519 -21.060 1.00 8.09 ? 56 ARG B CG 1 ATOM 4444 C CD . ARG B 1 56 ? 53.468 44.917 -21.977 1.00 9.19 ? 56 ARG B CD 1 ATOM 4445 N NE . ARG B 1 56 ? 52.181 44.866 -21.291 1.00 8.17 ? 56 ARG B NE 1 ATOM 4446 C CZ . ARG B 1 56 ? 51.001 44.817 -21.898 1.00 6.68 ? 56 ARG B CZ 1 ATOM 4447 N NH1 . ARG B 1 56 ? 50.927 44.802 -23.224 1.00 8.32 ? 56 ARG B NH1 1 ATOM 4448 N NH2 . ARG B 1 56 ? 49.890 44.813 -21.175 1.00 8.61 ? 56 ARG B NH2 1 ATOM 4449 N N . GLY B 1 57 ? 55.774 47.938 -19.387 1.00 10.43 ? 57 GLY B N 1 ATOM 4450 C CA . GLY B 1 57 ? 55.267 49.244 -18.997 1.00 10.70 ? 57 GLY B CA 1 ATOM 4451 C C . GLY B 1 57 ? 56.239 50.155 -18.266 1.00 11.41 ? 57 GLY B C 1 ATOM 4452 O O . GLY B 1 57 ? 57.406 49.820 -18.086 1.00 11.93 ? 57 GLY B O 1 ATOM 4453 N N . SER B 1 58 ? 55.742 51.313 -17.840 1.00 11.76 ? 58 SER B N 1 ATOM 4454 C CA . SER B 1 58 ? 56.553 52.300 -17.130 1.00 11.81 ? 58 SER B CA 1 ATOM 4455 C C . SER B 1 58 ? 56.560 52.078 -15.621 1.00 13.15 ? 58 SER B C 1 ATOM 4456 O O . SER B 1 58 ? 55.901 51.174 -15.106 1.00 12.97 ? 58 SER B O 1 ATOM 4457 C CB . SER B 1 58 ? 56.015 53.710 -17.397 1.00 13.04 ? 58 SER B CB 1 ATOM 4458 O OG . SER B 1 58 ? 55.955 54.000 -18.779 1.00 13.18 ? 58 SER B OG 1 ATOM 4459 N N . LEU B 1 59 ? 57.323 52.912 -14.919 1.00 12.37 ? 59 LEU B N 1 ATOM 4460 C CA . LEU B 1 59 ? 57.376 52.859 -13.465 1.00 13.15 ? 59 LEU B CA 1 ATOM 4461 C C . LEU B 1 59 ? 56.076 53.525 -13.020 1.00 13.10 ? 59 LEU B C 1 ATOM 4462 O O . LEU B 1 59 ? 55.528 54.361 -13.739 1.00 13.73 ? 59 LEU B O 1 ATOM 4463 C CB . LEU B 1 59 ? 58.569 53.666 -12.936 1.00 13.93 ? 59 LEU B CB 1 ATOM 4464 C CG . LEU B 1 59 ? 59.975 53.143 -13.239 1.00 15.58 ? 59 LEU B CG 1 ATOM 4465 C CD1 . LEU B 1 59 ? 61.007 54.210 -12.888 1.00 17.96 ? 59 LEU B CD1 1 ATOM 4466 C CD2 . LEU B 1 59 ? 60.229 51.869 -12.449 1.00 16.36 ? 59 LEU B CD2 1 ATOM 4467 N N . PRO B 1 60 ? 55.557 53.157 -11.839 1.00 13.19 ? 60 PRO B N 1 ATOM 4468 C CA . PRO B 1 60 ? 54.313 53.763 -11.360 1.00 13.98 ? 60 PRO B CA 1 ATOM 4469 C C . PRO B 1 60 ? 54.395 55.289 -11.276 1.00 13.92 ? 60 PRO B C 1 ATOM 4470 O O . PRO B 1 60 ? 53.405 55.986 -11.486 1.00 14.44 ? 60 PRO B O 1 ATOM 4471 C CB . PRO B 1 60 ? 54.123 53.118 -9.990 1.00 14.01 ? 60 PRO B CB 1 ATOM 4472 C CG . PRO B 1 60 ? 54.719 51.756 -10.185 1.00 13.30 ? 60 PRO B CG 1 ATOM 4473 C CD . PRO B 1 60 ? 55.985 52.060 -10.953 1.00 12.67 ? 60 PRO B CD 1 ATOM 4474 N N . THR B 1 61 ? 55.585 55.798 -10.976 1.00 14.90 ? 61 THR B N 1 ATOM 4475 C CA . THR B 1 61 ? 55.792 57.236 -10.854 1.00 15.99 ? 61 THR B CA 1 ATOM 4476 C C . THR B 1 61 ? 55.488 58.013 -12.135 1.00 15.28 ? 61 THR B C 1 ATOM 4477 O O . THR B 1 61 ? 55.258 59.224 -12.089 1.00 17.11 ? 61 THR B O 1 ATOM 4478 C CB . THR B 1 61 ? 57.237 57.546 -10.414 1.00 16.28 ? 61 THR B CB 1 ATOM 4479 O OG1 . THR B 1 61 ? 58.158 56.939 -11.328 1.00 17.87 ? 61 THR B OG1 1 ATOM 4480 C CG2 . THR B 1 61 ? 57.491 57.006 -9.015 1.00 16.77 ? 61 THR B CG2 1 ATOM 4481 N N . ALA B 1 62 ? 55.480 57.325 -13.273 1.00 14.70 ? 62 ALA B N 1 ATOM 4482 C CA . ALA B 1 62 ? 55.202 57.978 -14.550 1.00 14.78 ? 62 ALA B CA 1 ATOM 4483 C C . ALA B 1 62 ? 53.734 58.371 -14.679 1.00 14.91 ? 62 ALA B C 1 ATOM 4484 O O . ALA B 1 62 ? 53.382 59.227 -15.493 1.00 15.37 ? 62 ALA B O 1 ATOM 4485 C CB . ALA B 1 62 ? 55.598 57.066 -15.704 1.00 13.82 ? 62 ALA B CB 1 ATOM 4486 N N . TYR B 1 63 ? 52.881 57.736 -13.879 1.00 14.91 ? 63 TYR B N 1 ATOM 4487 C CA . TYR B 1 63 ? 51.449 58.016 -13.889 1.00 14.44 ? 63 TYR B CA 1 ATOM 4488 C C . TYR B 1 63 ? 50.945 58.100 -12.449 1.00 15.55 ? 63 TYR B C 1 ATOM 4489 O O . TYR B 1 63 ? 50.436 57.126 -11.897 1.00 14.01 ? 63 TYR B O 1 ATOM 4490 C CB . TYR B 1 63 ? 50.703 56.921 -14.660 1.00 13.84 ? 63 TYR B CB 1 ATOM 4491 C CG . TYR B 1 63 ? 51.161 56.793 -16.095 1.00 14.64 ? 63 TYR B CG 1 ATOM 4492 C CD1 . TYR B 1 63 ? 52.239 55.975 -16.437 1.00 13.75 ? 63 TYR B CD1 1 ATOM 4493 C CD2 . TYR B 1 63 ? 50.553 57.536 -17.106 1.00 15.19 ? 63 TYR B CD2 1 ATOM 4494 C CE1 . TYR B 1 63 ? 52.700 55.903 -17.751 1.00 12.58 ? 63 TYR B CE1 1 ATOM 4495 C CE2 . TYR B 1 63 ? 51.008 57.472 -18.419 1.00 14.46 ? 63 TYR B CE2 1 ATOM 4496 C CZ . TYR B 1 63 ? 52.081 56.656 -18.733 1.00 13.48 ? 63 TYR B CZ 1 ATOM 4497 O OH . TYR B 1 63 ? 52.543 56.613 -20.029 1.00 15.85 ? 63 TYR B OH 1 ATOM 4498 N N . PRO B 1 64 ? 51.072 59.284 -11.828 1.00 15.91 ? 64 PRO B N 1 ATOM 4499 C CA . PRO B 1 64 ? 50.669 59.587 -10.450 1.00 16.14 ? 64 PRO B CA 1 ATOM 4500 C C . PRO B 1 64 ? 49.293 59.111 -9.990 1.00 15.27 ? 64 PRO B C 1 ATOM 4501 O O . PRO B 1 64 ? 49.116 58.773 -8.820 1.00 15.39 ? 64 PRO B O 1 ATOM 4502 C CB . PRO B 1 64 ? 50.795 61.108 -10.385 1.00 18.18 ? 64 PRO B CB 1 ATOM 4503 C CG . PRO B 1 64 ? 51.932 61.380 -11.314 1.00 17.80 ? 64 PRO B CG 1 ATOM 4504 C CD . PRO B 1 64 ? 51.584 60.499 -12.490 1.00 17.17 ? 64 PRO B CD 1 ATOM 4505 N N . ASN B 1 65 ? 48.323 59.084 -10.897 1.00 15.63 ? 65 ASN B N 1 ATOM 4506 C CA . ASN B 1 65 ? 46.974 58.668 -10.532 1.00 16.01 ? 65 ASN B CA 1 ATOM 4507 C C . ASN B 1 65 ? 46.792 57.184 -10.225 1.00 16.20 ? 65 ASN B C 1 ATOM 4508 O O . ASN B 1 65 ? 45.711 56.763 -9.817 1.00 14.09 ? 65 ASN B O 1 ATOM 4509 C CB . ASN B 1 65 ? 45.986 59.119 -11.608 1.00 18.89 ? 65 ASN B CB 1 ATOM 4510 C CG . ASN B 1 65 ? 45.801 60.627 -11.621 1.00 21.02 ? 65 ASN B CG 1 ATOM 4511 O OD1 . ASN B 1 65 ? 45.278 61.204 -10.670 1.00 26.11 ? 65 ASN B OD1 1 ATOM 4512 N ND2 . ASN B 1 65 ? 46.244 61.272 -12.690 1.00 22.68 ? 65 ASN B ND2 1 ATOM 4513 N N . VAL B 1 66 ? 47.838 56.388 -10.417 1.00 15.80 ? 66 VAL B N 1 ATOM 4514 C CA . VAL B 1 66 ? 47.741 54.969 -10.093 1.00 13.75 ? 66 VAL B CA 1 ATOM 4515 C C . VAL B 1 66 ? 48.171 54.785 -8.638 1.00 14.02 ? 66 VAL B C 1 ATOM 4516 O O . VAL B 1 66 ? 48.126 53.679 -8.103 1.00 14.00 ? 66 VAL B O 1 ATOM 4517 C CB . VAL B 1 66 ? 48.659 54.091 -10.989 1.00 13.17 ? 66 VAL B CB 1 ATOM 4518 C CG1 . VAL B 1 66 ? 48.308 54.288 -12.453 1.00 12.73 ? 66 VAL B CG1 1 ATOM 4519 C CG2 . VAL B 1 66 ? 50.124 54.421 -10.731 1.00 14.56 ? 66 VAL B CG2 1 ATOM 4520 N N . LEU B 1 67 ? 48.571 55.879 -7.993 1.00 12.73 ? 67 LEU B N 1 ATOM 4521 C CA . LEU B 1 67 ? 49.043 55.809 -6.613 1.00 12.87 ? 67 LEU B CA 1 ATOM 4522 C C . LEU B 1 67 ? 48.043 56.193 -5.521 1.00 12.16 ? 67 LEU B C 1 ATOM 4523 O O . LEU B 1 67 ? 48.399 56.230 -4.340 1.00 12.20 ? 67 LEU B O 1 ATOM 4524 C CB . LEU B 1 67 ? 50.315 56.652 -6.472 1.00 13.33 ? 67 LEU B CB 1 ATOM 4525 C CG . LEU B 1 67 ? 51.481 56.232 -7.376 1.00 12.47 ? 67 LEU B CG 1 ATOM 4526 C CD1 . LEU B 1 67 ? 52.635 57.210 -7.225 1.00 15.07 ? 67 LEU B CD1 1 ATOM 4527 C CD2 . LEU B 1 67 ? 51.927 54.819 -7.021 1.00 14.60 ? 67 LEU B CD2 1 ATOM 4528 N N . THR B 1 68 ? 46.797 56.465 -5.900 1.00 12.52 ? 68 THR B N 1 ATOM 4529 C CA . THR B 1 68 ? 45.774 56.828 -4.922 1.00 13.55 ? 68 THR B CA 1 ATOM 4530 C C . THR B 1 68 ? 44.439 56.169 -5.248 1.00 13.52 ? 68 THR B C 1 ATOM 4531 O O . THR B 1 68 ? 44.176 55.811 -6.398 1.00 14.14 ? 68 THR B O 1 ATOM 4532 C CB . THR B 1 68 ? 45.537 58.357 -4.881 1.00 15.95 ? 68 THR B CB 1 ATOM 4533 O OG1 . THR B 1 68 ? 45.035 58.792 -6.149 1.00 15.89 ? 68 THR B OG1 1 ATOM 4534 C CG2 . THR B 1 68 ? 46.831 59.102 -4.562 1.00 15.07 ? 68 THR B CG2 1 ATOM 4535 N N . ALA B 1 69 ? 43.600 56.012 -4.229 1.00 13.25 ? 69 ALA B N 1 ATOM 4536 C CA . ALA B 1 69 ? 42.288 55.423 -4.423 1.00 13.91 ? 69 ALA B CA 1 ATOM 4537 C C . ALA B 1 69 ? 41.393 56.295 -5.293 1.00 14.64 ? 69 ALA B C 1 ATOM 4538 O O . ALA B 1 69 ? 40.657 55.783 -6.125 1.00 14.69 ? 69 ALA B O 1 ATOM 4539 C CB . ALA B 1 69 ? 41.621 55.160 -3.070 1.00 12.54 ? 69 ALA B CB 1 ATOM 4540 N N . ASP B 1 70 ? 41.441 57.613 -5.132 1.00 15.74 ? 70 ASP B N 1 ATOM 4541 C CA . ASP B 1 70 ? 40.574 58.431 -5.972 1.00 17.05 ? 70 ASP B CA 1 ATOM 4542 C C . ASP B 1 70 ? 41.056 58.550 -7.411 1.00 16.56 ? 70 ASP B C 1 ATOM 4543 O O . ASP B 1 70 ? 40.411 59.185 -8.241 1.00 17.67 ? 70 ASP B O 1 ATOM 4544 C CB . ASP B 1 70 ? 40.329 59.825 -5.373 1.00 20.44 ? 70 ASP B CB 1 ATOM 4545 C CG A ASP B 1 70 ? 41.578 60.474 -4.833 0.50 19.37 ? 70 ASP B CG 1 ATOM 4546 C CG B ASP B 1 70 ? 40.038 59.800 -3.894 0.50 20.16 ? 70 ASP B CG 1 ATOM 4547 O OD1 A ASP B 1 70 ? 42.636 60.415 -5.493 0.50 21.81 ? 70 ASP B OD1 1 ATOM 4548 O OD1 B ASP B 1 70 ? 39.739 58.719 -3.344 0.50 23.76 ? 70 ASP B OD1 1 ATOM 4549 O OD2 A ASP B 1 70 ? 41.490 61.066 -3.737 0.50 21.22 ? 70 ASP B OD2 1 ATOM 4550 O OD2 B ASP B 1 70 ? 40.128 60.879 -3.272 0.50 24.08 ? 70 ASP B OD2 1 ATOM 4551 N N . GLY B 1 71 ? 42.176 57.903 -7.712 1.00 15.49 ? 71 GLY B N 1 ATOM 4552 C CA . GLY B 1 71 ? 42.697 57.920 -9.068 1.00 13.90 ? 71 GLY B CA 1 ATOM 4553 C C . GLY B 1 71 ? 42.266 56.695 -9.861 1.00 12.70 ? 71 GLY B C 1 ATOM 4554 O O . GLY B 1 71 ? 42.547 56.584 -11.053 1.00 12.33 ? 71 GLY B O 1 ATOM 4555 N N . PHE B 1 72 ? 41.575 55.775 -9.196 1.00 12.97 ? 72 PHE B N 1 ATOM 4556 C CA . PHE B 1 72 ? 41.101 54.539 -9.822 1.00 11.59 ? 72 PHE B CA 1 ATOM 4557 C C . PHE B 1 72 ? 40.335 54.763 -11.123 1.00 11.16 ? 72 PHE B C 1 ATOM 4558 O O . PHE B 1 72 ? 40.694 54.225 -12.170 1.00 11.48 ? 72 PHE B O 1 ATOM 4559 C CB . PHE B 1 72 ? 40.217 53.757 -8.840 1.00 11.45 ? 72 PHE B CB 1 ATOM 4560 C CG . PHE B 1 72 ? 39.568 52.541 -9.444 1.00 11.10 ? 72 PHE B CG 1 ATOM 4561 C CD1 . PHE B 1 72 ? 40.343 51.506 -9.953 1.00 11.04 ? 72 PHE B CD1 1 ATOM 4562 C CD2 . PHE B 1 72 ? 38.181 52.438 -9.511 1.00 10.73 ? 72 PHE B CD2 1 ATOM 4563 C CE1 . PHE B 1 72 ? 39.749 50.384 -10.522 1.00 10.74 ? 72 PHE B CE1 1 ATOM 4564 C CE2 . PHE B 1 72 ? 37.573 51.318 -10.078 1.00 11.05 ? 72 PHE B CE2 1 ATOM 4565 C CZ . PHE B 1 72 ? 38.362 50.289 -10.585 1.00 11.02 ? 72 PHE B CZ 1 ATOM 4566 N N . VAL B 1 73 ? 39.275 55.558 -11.059 1.00 11.35 ? 73 VAL B N 1 ATOM 4567 C CA . VAL B 1 73 ? 38.477 55.826 -12.247 1.00 12.16 ? 73 VAL B CA 1 ATOM 4568 C C . VAL B 1 73 ? 39.281 56.582 -13.303 1.00 12.19 ? 73 VAL B C 1 ATOM 4569 O O . VAL B 1 73 ? 39.172 56.296 -14.495 1.00 11.94 ? 73 VAL B O 1 ATOM 4570 C CB . VAL B 1 73 ? 37.206 56.624 -11.885 1.00 12.30 ? 73 VAL B CB 1 ATOM 4571 C CG1 . VAL B 1 73 ? 36.469 57.051 -13.147 1.00 14.46 ? 73 VAL B CG1 1 ATOM 4572 C CG2 . VAL B 1 73 ? 36.303 55.766 -11.013 1.00 15.09 ? 73 VAL B CG2 1 ATOM 4573 N N . TYR B 1 74 ? 40.098 57.535 -12.865 1.00 13.09 ? 74 TYR B N 1 ATOM 4574 C CA . TYR B 1 74 ? 40.913 58.322 -13.784 1.00 12.69 ? 74 TYR B CA 1 ATOM 4575 C C . TYR B 1 74 ? 41.724 57.452 -14.743 1.00 13.40 ? 74 TYR B C 1 ATOM 4576 O O . TYR B 1 74 ? 41.724 57.681 -15.951 1.00 12.69 ? 74 TYR B O 1 ATOM 4577 C CB . TYR B 1 74 ? 41.873 59.225 -13.004 1.00 15.70 ? 74 TYR B CB 1 ATOM 4578 C CG . TYR B 1 74 ? 42.763 60.073 -13.888 1.00 18.56 ? 74 TYR B CG 1 ATOM 4579 C CD1 . TYR B 1 74 ? 42.340 61.321 -14.348 1.00 21.02 ? 74 TYR B CD1 1 ATOM 4580 C CD2 . TYR B 1 74 ? 44.024 59.620 -14.281 1.00 19.52 ? 74 TYR B CD2 1 ATOM 4581 C CE1 . TYR B 1 74 ? 43.153 62.099 -15.177 1.00 22.23 ? 74 TYR B CE1 1 ATOM 4582 C CE2 . TYR B 1 74 ? 44.843 60.387 -15.109 1.00 22.11 ? 74 TYR B CE2 1 ATOM 4583 C CZ . TYR B 1 74 ? 44.402 61.625 -15.552 1.00 22.41 ? 74 TYR B CZ 1 ATOM 4584 O OH . TYR B 1 74 ? 45.210 62.385 -16.369 1.00 23.34 ? 74 TYR B OH 1 ATOM 4585 N N . ASN B 1 75 ? 42.419 56.455 -14.203 1.00 12.31 ? 75 ASN B N 1 ATOM 4586 C CA . ASN B 1 75 ? 43.241 55.578 -15.031 1.00 12.30 ? 75 ASN B CA 1 ATOM 4587 C C . ASN B 1 75 ? 42.422 54.888 -16.117 1.00 11.08 ? 75 ASN B C 1 ATOM 4588 O O . ASN B 1 75 ? 42.880 54.745 -17.250 1.00 10.85 ? 75 ASN B O 1 ATOM 4589 C CB . ASN B 1 75 ? 43.925 54.531 -14.154 1.00 12.34 ? 75 ASN B CB 1 ATOM 4590 C CG . ASN B 1 75 ? 44.718 55.151 -13.023 1.00 13.09 ? 75 ASN B CG 1 ATOM 4591 O OD1 . ASN B 1 75 ? 44.752 54.619 -11.911 1.00 14.93 ? 75 ASN B OD1 1 ATOM 4592 N ND2 . ASN B 1 75 ? 45.365 56.279 -13.299 1.00 10.59 ? 75 ASN B ND2 1 ATOM 4593 N N . LEU B 1 76 ? 41.213 54.458 -15.769 1.00 10.55 ? 76 LEU B N 1 ATOM 4594 C CA . LEU B 1 76 ? 40.343 53.789 -16.731 1.00 10.28 ? 76 LEU B CA 1 ATOM 4595 C C . LEU B 1 76 ? 39.830 54.759 -17.796 1.00 11.25 ? 76 LEU B C 1 ATOM 4596 O O . LEU B 1 76 ? 39.586 54.367 -18.934 1.00 10.25 ? 76 LEU B O 1 ATOM 4597 C CB . LEU B 1 76 ? 39.152 53.143 -16.019 1.00 9.94 ? 76 LEU B CB 1 ATOM 4598 C CG . LEU B 1 76 ? 39.444 52.027 -15.013 1.00 10.49 ? 76 LEU B CG 1 ATOM 4599 C CD1 . LEU B 1 76 ? 38.140 51.560 -14.386 1.00 10.41 ? 76 LEU B CD1 1 ATOM 4600 C CD2 . LEU B 1 76 ? 40.143 50.868 -15.710 1.00 10.48 ? 76 LEU B CD2 1 ATOM 4601 N N . GLN B 1 77 ? 39.674 56.027 -17.426 1.00 12.43 ? 77 GLN B N 1 ATOM 4602 C CA . GLN B 1 77 ? 39.183 57.036 -18.367 1.00 13.10 ? 77 GLN B CA 1 ATOM 4603 C C . GLN B 1 77 ? 40.235 57.526 -19.360 1.00 13.70 ? 77 GLN B C 1 ATOM 4604 O O . GLN B 1 77 ? 39.896 57.993 -20.447 1.00 14.56 ? 77 GLN B O 1 ATOM 4605 C CB . GLN B 1 77 ? 38.640 58.252 -17.612 1.00 14.11 ? 77 GLN B CB 1 ATOM 4606 C CG . GLN B 1 77 ? 37.442 57.977 -16.729 1.00 12.66 ? 77 GLN B CG 1 ATOM 4607 C CD . GLN B 1 77 ? 37.120 59.162 -15.838 1.00 13.65 ? 77 GLN B CD 1 ATOM 4608 O OE1 . GLN B 1 77 ? 38.000 59.696 -15.163 1.00 14.09 ? 77 GLN B OE1 1 ATOM 4609 N NE2 . GLN B 1 77 ? 35.858 59.574 -15.826 1.00 13.62 ? 77 GLN B NE2 1 ATOM 4610 N N . GLN B 1 78 ? 41.507 57.432 -18.988 1.00 15.35 ? 78 GLN B N 1 ATOM 4611 C CA . GLN B 1 78 ? 42.579 57.911 -19.855 1.00 15.77 ? 78 GLN B CA 1 ATOM 4612 C C . GLN B 1 78 ? 42.714 57.184 -21.185 1.00 16.87 ? 78 GLN B C 1 ATOM 4613 O O . GLN B 1 78 ? 42.685 55.956 -21.250 1.00 16.60 ? 78 GLN B O 1 ATOM 4614 C CB . GLN B 1 78 ? 43.911 57.883 -19.103 1.00 16.92 ? 78 GLN B CB 1 ATOM 4615 C CG A GLN B 1 78 ? 43.887 58.747 -17.855 0.50 15.71 ? 78 GLN B CG 1 ATOM 4616 C CG B GLN B 1 78 ? 45.093 58.444 -19.886 0.50 16.14 ? 78 GLN B CG 1 ATOM 4617 C CD A GLN B 1 78 ? 43.163 60.068 -18.078 0.50 16.18 ? 78 GLN B CD 1 ATOM 4618 C CD B GLN B 1 78 ? 46.362 58.499 -19.060 0.50 16.71 ? 78 GLN B CD 1 ATOM 4619 O OE1 A GLN B 1 78 ? 43.601 60.909 -18.867 0.50 16.32 ? 78 GLN B OE1 1 ATOM 4620 O OE1 B GLN B 1 78 ? 46.673 57.565 -18.319 0.50 17.00 ? 78 GLN B OE1 1 ATOM 4621 N NE2 A GLN B 1 78 ? 42.040 60.249 -17.388 0.50 11.64 ? 78 GLN B NE2 1 ATOM 4622 N NE2 B GLN B 1 78 ? 47.242 59.494 -19.031 0.50 12.38 ? 78 GLN B NE2 1 ATOM 4623 N N . GLU B 1 79 ? 42.864 57.963 -22.251 1.00 17.08 ? 79 GLU B N 1 ATOM 4624 C CA . GLU B 1 79 ? 42.999 57.406 -23.585 1.00 18.09 ? 79 GLU B CA 1 ATOM 4625 C C . GLU B 1 79 ? 44.216 56.490 -23.646 1.00 15.73 ? 79 GLU B C 1 ATOM 4626 O O . GLU B 1 79 ? 45.249 56.765 -23.034 1.00 14.51 ? 79 GLU B O 1 ATOM 4627 C CB . GLU B 1 79 ? 43.135 58.529 -24.617 1.00 21.61 ? 79 GLU B CB 1 ATOM 4628 C CG . GLU B 1 79 ? 42.390 58.244 -25.907 1.00 28.11 ? 79 GLU B CG 1 ATOM 4629 C CD . GLU B 1 79 ? 40.884 58.230 -25.710 1.00 30.75 ? 79 GLU B CD 1 ATOM 4630 O OE1 . GLU B 1 79 ? 40.201 57.435 -26.388 1.00 33.48 ? 79 GLU B OE1 1 ATOM 4631 O OE2 . GLU B 1 79 ? 40.382 59.022 -24.883 1.00 34.09 ? 79 GLU B OE2 1 ATOM 4632 N N . ASP B 1 80 ? 44.079 55.398 -24.388 1.00 15.04 ? 80 ASP B N 1 ATOM 4633 C CA . ASP B 1 80 ? 45.146 54.420 -24.535 1.00 15.11 ? 80 ASP B CA 1 ATOM 4634 C C . ASP B 1 80 ? 46.086 54.833 -25.662 1.00 15.24 ? 80 ASP B C 1 ATOM 4635 O O . ASP B 1 80 ? 45.753 54.681 -26.839 1.00 15.89 ? 80 ASP B O 1 ATOM 4636 C CB . ASP B 1 80 ? 44.545 53.047 -24.844 1.00 15.25 ? 80 ASP B CB 1 ATOM 4637 C CG . ASP B 1 80 ? 45.576 51.938 -24.821 1.00 16.19 ? 80 ASP B CG 1 ATOM 4638 O OD1 . ASP B 1 80 ? 46.787 52.238 -24.908 1.00 15.09 ? 80 ASP B OD1 1 ATOM 4639 O OD2 . ASP B 1 80 ? 45.169 50.761 -24.731 1.00 16.38 ? 80 ASP B OD2 1 ATOM 4640 N N . ASP B 1 81 ? 47.257 55.353 -25.301 1.00 15.34 ? 81 ASP B N 1 ATOM 4641 C CA . ASP B 1 81 ? 48.232 55.780 -26.300 1.00 15.76 ? 81 ASP B CA 1 ATOM 4642 C C . ASP B 1 81 ? 49.332 54.747 -26.504 1.00 15.18 ? 81 ASP B C 1 ATOM 4643 O O . ASP B 1 81 ? 50.353 55.037 -27.125 1.00 14.92 ? 81 ASP B O 1 ATOM 4644 C CB . ASP B 1 81 ? 48.862 57.122 -25.909 1.00 16.89 ? 81 ASP B CB 1 ATOM 4645 C CG . ASP B 1 81 ? 49.642 57.053 -24.611 1.00 19.72 ? 81 ASP B CG 1 ATOM 4646 O OD1 . ASP B 1 81 ? 49.893 55.937 -24.111 1.00 17.63 ? 81 ASP B OD1 1 ATOM 4647 O OD2 . ASP B 1 81 ? 50.015 58.126 -24.094 1.00 20.81 ? 81 ASP B OD2 1 ATOM 4648 N N . GLY B 1 82 ? 49.119 53.544 -25.976 1.00 15.20 ? 82 GLY B N 1 ATOM 4649 C CA . GLY B 1 82 ? 50.101 52.483 -26.118 1.00 14.12 ? 82 GLY B CA 1 ATOM 4650 C C . GLY B 1 82 ? 51.152 52.464 -25.025 1.00 14.49 ? 82 GLY B C 1 ATOM 4651 O O . GLY B 1 82 ? 51.950 51.531 -24.941 1.00 14.75 ? 82 GLY B O 1 ATOM 4652 N N . LYS B 1 83 ? 51.152 53.489 -24.180 1.00 14.42 ? 83 LYS B N 1 ATOM 4653 C CA . LYS B 1 83 ? 52.127 53.578 -23.098 1.00 14.48 ? 83 LYS B CA 1 ATOM 4654 C C . LYS B 1 83 ? 51.482 53.690 -21.718 1.00 12.53 ? 83 LYS B C 1 ATOM 4655 O O . LYS B 1 83 ? 52.119 53.410 -20.706 1.00 14.61 ? 83 LYS B O 1 ATOM 4656 C CB . LYS B 1 83 ? 53.048 54.779 -23.339 1.00 17.97 ? 83 LYS B CB 1 ATOM 4657 C CG . LYS B 1 83 ? 53.840 54.706 -24.641 1.00 22.79 ? 83 LYS B CG 1 ATOM 4658 C CD . LYS B 1 83 ? 54.833 53.547 -24.620 1.00 25.93 ? 83 LYS B CD 1 ATOM 4659 C CE . LYS B 1 83 ? 55.688 53.479 -25.887 1.00 28.17 ? 83 LYS B CE 1 ATOM 4660 N NZ . LYS B 1 83 ? 54.955 52.973 -27.084 1.00 30.57 ? 83 LYS B NZ 1 ATOM 4661 N N . THR B 1 84 ? 50.220 54.100 -21.682 1.00 11.48 ? 84 THR B N 1 ATOM 4662 C CA . THR B 1 84 ? 49.488 54.261 -20.427 1.00 11.31 ? 84 THR B CA 1 ATOM 4663 C C . THR B 1 84 ? 49.358 52.955 -19.639 1.00 11.72 ? 84 THR B C 1 ATOM 4664 O O . THR B 1 84 ? 49.359 51.868 -20.216 1.00 12.04 ? 84 THR B O 1 ATOM 4665 C CB . THR B 1 84 ? 48.088 54.841 -20.693 1.00 11.16 ? 84 THR B CB 1 ATOM 4666 O OG1 . THR B 1 84 ? 47.493 54.154 -21.798 1.00 12.88 ? 84 THR B OG1 1 ATOM 4667 C CG2 . THR B 1 84 ? 48.176 56.331 -21.014 1.00 12.67 ? 84 THR B CG2 1 ATOM 4668 N N . PRO B 1 85 ? 49.228 53.049 -18.301 1.00 12.23 ? 85 PRO B N 1 ATOM 4669 C CA . PRO B 1 85 ? 49.105 51.876 -17.423 1.00 11.37 ? 85 PRO B CA 1 ATOM 4670 C C . PRO B 1 85 ? 47.870 51.005 -17.634 1.00 11.68 ? 85 PRO B C 1 ATOM 4671 O O . PRO B 1 85 ? 47.830 49.862 -17.183 1.00 10.55 ? 85 PRO B O 1 ATOM 4672 C CB . PRO B 1 85 ? 49.160 52.485 -16.021 1.00 10.24 ? 85 PRO B CB 1 ATOM 4673 C CG . PRO B 1 85 ? 48.542 53.840 -16.217 1.00 11.86 ? 85 PRO B CG 1 ATOM 4674 C CD . PRO B 1 85 ? 49.167 54.297 -17.516 1.00 10.98 ? 85 PRO B CD 1 ATOM 4675 N N . VAL B 1 86 ? 46.867 51.545 -18.315 1.00 10.26 ? 86 VAL B N 1 ATOM 4676 C CA . VAL B 1 86 ? 45.649 50.795 -18.587 1.00 9.57 ? 86 VAL B CA 1 ATOM 4677 C C . VAL B 1 86 ? 45.535 50.500 -20.078 1.00 11.03 ? 86 VAL B C 1 ATOM 4678 O O . VAL B 1 86 ? 45.303 51.403 -20.884 1.00 11.78 ? 86 VAL B O 1 ATOM 4679 C CB . VAL B 1 86 ? 44.395 51.574 -18.135 1.00 9.28 ? 86 VAL B CB 1 ATOM 4680 C CG1 . VAL B 1 86 ? 43.131 50.789 -18.490 1.00 9.51 ? 86 VAL B CG1 1 ATOM 4681 C CG2 . VAL B 1 86 ? 44.457 51.826 -16.639 1.00 9.78 ? 86 VAL B CG2 1 ATOM 4682 N N . GLU B 1 87 ? 45.721 49.235 -20.445 1.00 8.79 ? 87 GLU B N 1 ATOM 4683 C CA . GLU B 1 87 ? 45.611 48.834 -21.838 1.00 9.28 ? 87 GLU B CA 1 ATOM 4684 C C . GLU B 1 87 ? 44.193 48.346 -22.096 1.00 9.40 ? 87 GLU B C 1 ATOM 4685 O O . GLU B 1 87 ? 43.703 47.431 -21.425 1.00 9.78 ? 87 GLU B O 1 ATOM 4686 C CB . GLU B 1 87 ? 46.606 47.719 -22.180 1.00 10.63 ? 87 GLU B CB 1 ATOM 4687 C CG . GLU B 1 87 ? 46.294 47.044 -23.517 1.00 12.35 ? 87 GLU B CG 1 ATOM 4688 C CD . GLU B 1 87 ? 47.417 46.169 -24.031 1.00 12.58 ? 87 GLU B CD 1 ATOM 4689 O OE1 . GLU B 1 87 ? 48.258 45.728 -23.224 1.00 12.58 ? 87 GLU B OE1 1 ATOM 4690 O OE2 . GLU B 1 87 ? 47.451 45.911 -25.253 1.00 14.33 ? 87 GLU B OE2 1 ATOM 4691 N N . ARG B 1 88 ? 43.541 48.963 -23.072 1.00 8.70 ? 88 ARG B N 1 ATOM 4692 C CA . ARG B 1 88 ? 42.178 48.609 -23.428 1.00 8.96 ? 88 ARG B CA 1 ATOM 4693 C C . ARG B 1 88 ? 42.104 47.492 -24.456 1.00 8.91 ? 88 ARG B C 1 ATOM 4694 O O . ARG B 1 88 ? 42.944 47.396 -25.351 1.00 10.29 ? 88 ARG B O 1 ATOM 4695 C CB . ARG B 1 88 ? 41.451 49.824 -24.014 1.00 10.51 ? 88 ARG B CB 1 ATOM 4696 C CG . ARG B 1 88 ? 41.425 51.057 -23.139 1.00 8.76 ? 88 ARG B CG 1 ATOM 4697 C CD . ARG B 1 88 ? 40.660 52.176 -23.841 1.00 10.97 ? 88 ARG B CD 1 ATOM 4698 N NE . ARG B 1 88 ? 40.542 53.364 -23.007 1.00 12.46 ? 88 ARG B NE 1 ATOM 4699 C CZ . ARG B 1 88 ? 39.760 54.400 -23.289 1.00 13.99 ? 88 ARG B CZ 1 ATOM 4700 N NH1 . ARG B 1 88 ? 39.018 54.398 -24.391 1.00 14.09 ? 88 ARG B NH1 1 ATOM 4701 N NH2 . ARG B 1 88 ? 39.715 55.439 -22.464 1.00 15.50 ? 88 ARG B NH2 1 ATOM 4702 N N . PHE B 1 89 ? 41.092 46.643 -24.319 1.00 8.41 ? 89 PHE B N 1 ATOM 4703 C CA . PHE B 1 89 ? 40.857 45.586 -25.288 1.00 8.84 ? 89 PHE B CA 1 ATOM 4704 C C . PHE B 1 89 ? 39.385 45.215 -25.245 1.00 7.82 ? 89 PHE B C 1 ATOM 4705 O O . PHE B 1 89 ? 38.686 45.530 -24.284 1.00 9.72 ? 89 PHE B O 1 ATOM 4706 C CB . PHE B 1 89 ? 41.784 44.370 -25.059 1.00 10.02 ? 89 PHE B CB 1 ATOM 4707 C CG . PHE B 1 89 ? 41.447 43.522 -23.862 1.00 10.42 ? 89 PHE B CG 1 ATOM 4708 C CD1 . PHE B 1 89 ? 40.596 42.426 -23.984 1.00 8.90 ? 89 PHE B CD1 1 ATOM 4709 C CD2 . PHE B 1 89 ? 42.051 43.763 -22.632 1.00 11.18 ? 89 PHE B CD2 1 ATOM 4710 C CE1 . PHE B 1 89 ? 40.358 41.577 -22.904 1.00 10.00 ? 89 PHE B CE1 1 ATOM 4711 C CE2 . PHE B 1 89 ? 41.820 42.920 -21.543 1.00 10.98 ? 89 PHE B CE2 1 ATOM 4712 C CZ . PHE B 1 89 ? 40.975 41.826 -21.680 1.00 10.49 ? 89 PHE B CZ 1 ATOM 4713 N N . VAL B 1 90 ? 38.901 44.608 -26.321 1.00 8.20 ? 90 VAL B N 1 ATOM 4714 C CA . VAL B 1 90 ? 37.506 44.202 -26.398 1.00 8.58 ? 90 VAL B CA 1 ATOM 4715 C C . VAL B 1 90 ? 37.488 42.726 -26.756 1.00 8.45 ? 90 VAL B C 1 ATOM 4716 O O . VAL B 1 90 ? 38.108 42.321 -27.739 1.00 9.65 ? 90 VAL B O 1 ATOM 4717 C CB . VAL B 1 90 ? 36.756 44.993 -27.494 1.00 9.99 ? 90 VAL B CB 1 ATOM 4718 C CG1 . VAL B 1 90 ? 35.279 44.633 -27.480 1.00 10.61 ? 90 VAL B CG1 1 ATOM 4719 C CG2 . VAL B 1 90 ? 36.941 46.483 -27.276 1.00 10.89 ? 90 VAL B CG2 1 ATOM 4720 N N . SER B 1 91 ? 36.795 41.916 -25.962 1.00 8.30 ? 91 SER B N 1 ATOM 4721 C CA . SER B 1 91 ? 36.735 40.487 -26.256 1.00 7.90 ? 91 SER B CA 1 ATOM 4722 C C . SER B 1 91 ? 35.906 40.271 -27.519 1.00 8.36 ? 91 SER B C 1 ATOM 4723 O O . SER B 1 91 ? 35.166 41.159 -27.951 1.00 8.27 ? 91 SER B O 1 ATOM 4724 C CB . SER B 1 91 ? 36.112 39.708 -25.091 1.00 8.09 ? 91 SER B CB 1 ATOM 4725 O OG . SER B 1 91 ? 34.698 39.823 -25.075 1.00 8.11 ? 91 SER B OG 1 ATOM 4726 N N . GLU B 1 92 ? 36.036 39.089 -28.110 1.00 7.11 ? 92 GLU B N 1 ATOM 4727 C CA . GLU B 1 92 ? 35.295 38.757 -29.319 1.00 8.92 ? 92 GLU B CA 1 ATOM 4728 C C . GLU B 1 92 ? 33.795 38.694 -29.025 1.00 10.19 ? 92 GLU B C 1 ATOM 4729 O O . GLU B 1 92 ? 32.972 38.719 -29.944 1.00 10.79 ? 92 GLU B O 1 ATOM 4730 C CB . GLU B 1 92 ? 35.795 37.425 -29.888 1.00 8.93 ? 92 GLU B CB 1 ATOM 4731 C CG A GLU B 1 92 ? 37.161 37.521 -30.557 0.50 11.14 ? 92 GLU B CG 1 ATOM 4732 C CG B GLU B 1 92 ? 35.217 37.121 -31.282 0.50 11.31 ? 92 GLU B CG 1 ATOM 4733 C CD A GLU B 1 92 ? 37.780 36.163 -30.834 0.50 12.96 ? 92 GLU B CD 1 ATOM 4734 C CD B GLU B 1 92 ? 35.713 35.797 -31.829 0.50 13.31 ? 92 GLU B CD 1 ATOM 4735 O OE1 A GLU B 1 92 ? 37.024 35.213 -31.125 0.50 14.23 ? 92 GLU B OE1 1 ATOM 4736 O OE1 B GLU B 1 92 ? 36.893 35.463 -31.594 0.50 14.37 ? 92 GLU B OE1 1 ATOM 4737 O OE2 A GLU B 1 92 ? 39.024 36.050 -30.771 0.50 16.96 ? 92 GLU B OE2 1 ATOM 4738 O OE2 B GLU B 1 92 ? 34.922 35.095 -32.493 0.50 17.47 ? 92 GLU B OE2 1 ATOM 4739 N N . ASP B 1 93 ? 33.446 38.628 -27.740 1.00 8.48 ? 93 ASP B N 1 ATOM 4740 C CA . ASP B 1 93 ? 32.045 38.589 -27.328 1.00 9.37 ? 93 ASP B CA 1 ATOM 4741 C C . ASP B 1 93 ? 31.455 39.994 -27.430 1.00 10.02 ? 93 ASP B C 1 ATOM 4742 O O . ASP B 1 93 ? 30.235 40.165 -27.398 1.00 12.13 ? 93 ASP B O 1 ATOM 4743 C CB . ASP B 1 93 ? 31.902 38.119 -25.876 1.00 9.29 ? 93 ASP B CB 1 ATOM 4744 C CG . ASP B 1 93 ? 32.781 36.935 -25.549 1.00 9.32 ? 93 ASP B CG 1 ATOM 4745 O OD1 . ASP B 1 93 ? 33.960 37.154 -25.187 1.00 9.65 ? 93 ASP B OD1 1 ATOM 4746 O OD2 . ASP B 1 93 ? 32.294 35.787 -25.659 1.00 10.22 ? 93 ASP B OD2 1 ATOM 4747 N N . GLY B 1 94 ? 32.334 40.990 -27.528 1.00 10.29 ? 94 GLY B N 1 ATOM 4748 C CA . GLY B 1 94 ? 31.906 42.377 -27.617 1.00 11.07 ? 94 GLY B CA 1 ATOM 4749 C C . GLY B 1 94 ? 31.917 43.114 -26.285 1.00 11.86 ? 94 GLY B C 1 ATOM 4750 O O . GLY B 1 94 ? 31.309 44.176 -26.155 1.00 12.38 ? 94 GLY B O 1 ATOM 4751 N N . ILE B 1 95 ? 32.622 42.568 -25.299 1.00 10.34 ? 95 ILE B N 1 ATOM 4752 C CA . ILE B 1 95 ? 32.685 43.176 -23.968 1.00 9.20 ? 95 ILE B CA 1 ATOM 4753 C C . ILE B 1 95 ? 34.006 43.909 -23.718 1.00 9.56 ? 95 ILE B C 1 ATOM 4754 O O . ILE B 1 95 ? 35.081 43.314 -23.794 1.00 10.32 ? 95 ILE B O 1 ATOM 4755 C CB . ILE B 1 95 ? 32.483 42.093 -22.878 1.00 8.52 ? 95 ILE B CB 1 ATOM 4756 C CG1 . ILE B 1 95 ? 31.122 41.410 -23.073 1.00 7.97 ? 95 ILE B CG1 1 ATOM 4757 C CG2 . ILE B 1 95 ? 32.579 42.707 -21.488 1.00 7.87 ? 95 ILE B CG2 1 ATOM 4758 C CD1 . ILE B 1 95 ? 29.925 42.365 -23.045 1.00 8.79 ? 95 ILE B CD1 1 ATOM 4759 N N . ASP B 1 96 ? 33.916 45.205 -23.421 1.00 9.01 ? 96 ASP B N 1 ATOM 4760 C CA . ASP B 1 96 ? 35.100 46.023 -23.160 1.00 9.07 ? 96 ASP B CA 1 ATOM 4761 C C . ASP B 1 96 ? 35.841 45.534 -21.922 1.00 8.80 ? 96 ASP B C 1 ATOM 4762 O O . ASP B 1 96 ? 35.225 45.093 -20.951 1.00 8.35 ? 96 ASP B O 1 ATOM 4763 C CB . ASP B 1 96 ? 34.711 47.494 -22.981 1.00 8.76 ? 96 ASP B CB 1 ATOM 4764 C CG . ASP B 1 96 ? 34.202 48.126 -24.263 1.00 12.18 ? 96 ASP B CG 1 ATOM 4765 O OD1 . ASP B 1 96 ? 34.432 47.550 -25.348 1.00 11.77 ? 96 ASP B OD1 1 ATOM 4766 O OD2 . ASP B 1 96 ? 33.585 49.211 -24.184 1.00 12.57 ? 96 ASP B OD2 1 ATOM 4767 N N . ASN B 1 97 ? 37.166 45.633 -21.951 1.00 8.55 ? 97 ASN B N 1 ATOM 4768 C CA . ASN B 1 97 ? 37.985 45.153 -20.846 1.00 7.43 ? 97 ASN B CA 1 ATOM 4769 C C . ASN B 1 97 ? 39.326 45.885 -20.803 1.00 8.39 ? 97 ASN B C 1 ATOM 4770 O O . ASN B 1 97 ? 39.652 46.664 -21.703 1.00 6.92 ? 97 ASN B O 1 ATOM 4771 C CB . ASN B 1 97 ? 38.235 43.655 -21.033 1.00 6.84 ? 97 ASN B CB 1 ATOM 4772 C CG . ASN B 1 97 ? 38.220 42.893 -19.728 1.00 5.75 ? 97 ASN B CG 1 ATOM 4773 O OD1 . ASN B 1 97 ? 38.692 43.383 -18.705 1.00 8.39 ? 97 ASN B OD1 1 ATOM 4774 N ND2 . ASN B 1 97 ? 37.685 41.674 -19.762 1.00 8.22 ? 97 ASN B ND2 1 ATOM 4775 N N . VAL B 1 98 ? 40.103 45.638 -19.752 1.00 7.05 ? 98 VAL B N 1 ATOM 4776 C CA . VAL B 1 98 ? 41.410 46.268 -19.620 1.00 7.12 ? 98 VAL B CA 1 ATOM 4777 C C . VAL B 1 98 ? 42.387 45.361 -18.881 1.00 7.04 ? 98 VAL B C 1 ATOM 4778 O O . VAL B 1 98 ? 41.980 44.442 -18.169 1.00 9.14 ? 98 VAL B O 1 ATOM 4779 C CB . VAL B 1 98 ? 41.341 47.609 -18.830 1.00 7.28 ? 98 VAL B CB 1 ATOM 4780 C CG1 . VAL B 1 98 ? 40.338 48.556 -19.471 1.00 8.00 ? 98 VAL B CG1 1 ATOM 4781 C CG2 . VAL B 1 98 ? 40.973 47.342 -17.373 1.00 8.71 ? 98 VAL B CG2 1 ATOM 4782 N N . ARG B 1 99 ? 43.678 45.612 -19.080 1.00 7.17 ? 99 ARG B N 1 ATOM 4783 C CA . ARG B 1 99 ? 44.725 44.875 -18.386 1.00 7.78 ? 99 ARG B CA 1 ATOM 4784 C C . ARG B 1 99 ? 45.844 45.859 -18.071 1.00 7.83 ? 99 ARG B C 1 ATOM 4785 O O . ARG B 1 99 ? 46.007 46.870 -18.754 1.00 8.33 ? 99 ARG B O 1 ATOM 4786 C CB . ARG B 1 99 ? 45.265 43.700 -19.221 1.00 9.37 ? 99 ARG B CB 1 ATOM 4787 C CG . ARG B 1 99 ? 45.885 44.058 -20.562 1.00 8.25 ? 99 ARG B CG 1 ATOM 4788 C CD . ARG B 1 99 ? 46.735 42.891 -21.075 1.00 10.41 ? 99 ARG B CD 1 ATOM 4789 N NE . ARG B 1 99 ? 47.018 42.996 -22.503 1.00 8.63 ? 99 ARG B NE 1 ATOM 4790 C CZ . ARG B 1 99 ? 48.071 42.451 -23.102 1.00 9.97 ? 99 ARG B CZ 1 ATOM 4791 N NH1 . ARG B 1 99 ? 48.961 41.754 -22.401 1.00 8.58 ? 99 ARG B NH1 1 ATOM 4792 N NH2 . ARG B 1 99 ? 48.240 42.609 -24.408 1.00 12.21 ? 99 ARG B NH2 1 ATOM 4793 N N . GLY B 1 100 ? 46.603 45.574 -17.022 1.00 7.99 ? 100 GLY B N 1 ATOM 4794 C CA . GLY B 1 100 ? 47.684 46.464 -16.647 1.00 7.06 ? 100 GLY B CA 1 ATOM 4795 C C . GLY B 1 100 ? 48.878 46.447 -17.582 1.00 7.93 ? 100 GLY B C 1 ATOM 4796 O O . GLY B 1 100 ? 49.154 45.449 -18.244 1.00 8.39 ? 100 GLY B O 1 ATOM 4797 N N . ARG B 1 101 ? 49.589 47.569 -17.624 1.00 7.98 ? 101 ARG B N 1 ATOM 4798 C CA . ARG B 1 101 ? 50.780 47.728 -18.455 1.00 7.34 ? 101 ARG B CA 1 ATOM 4799 C C . ARG B 1 101 ? 51.650 48.735 -17.711 1.00 9.21 ? 101 ARG B C 1 ATOM 4800 O O . ARG B 1 101 ? 51.778 49.893 -18.108 1.00 10.37 ? 101 ARG B O 1 ATOM 4801 C CB . ARG B 1 101 ? 50.388 48.262 -19.837 1.00 8.94 ? 101 ARG B CB 1 ATOM 4802 C CG . ARG B 1 101 ? 51.552 48.439 -20.805 1.00 7.80 ? 101 ARG B CG 1 ATOM 4803 C CD . ARG B 1 101 ? 51.040 48.748 -22.201 1.00 10.94 ? 101 ARG B CD 1 ATOM 4804 N NE . ARG B 1 101 ? 50.138 49.895 -22.192 1.00 12.61 ? 101 ARG B NE 1 ATOM 4805 C CZ . ARG B 1 101 ? 49.313 50.213 -23.183 1.00 13.12 ? 101 ARG B CZ 1 ATOM 4806 N NH1 . ARG B 1 101 ? 49.267 49.469 -24.284 1.00 12.80 ? 101 ARG B NH1 1 ATOM 4807 N NH2 . ARG B 1 101 ? 48.523 51.272 -23.067 1.00 13.80 ? 101 ARG B NH2 1 ATOM 4808 N N . VAL B 1 102 ? 52.240 48.270 -16.617 1.00 8.77 ? 102 VAL B N 1 ATOM 4809 C CA . VAL B 1 102 ? 53.058 49.110 -15.755 1.00 9.77 ? 102 VAL B CA 1 ATOM 4810 C C . VAL B 1 102 ? 53.753 48.191 -14.752 1.00 9.63 ? 102 VAL B C 1 ATOM 4811 O O . VAL B 1 102 ? 53.321 47.057 -14.551 1.00 9.01 ? 102 VAL B O 1 ATOM 4812 C CB . VAL B 1 102 ? 52.144 50.121 -15.007 1.00 9.47 ? 102 VAL B CB 1 ATOM 4813 C CG1 . VAL B 1 102 ? 51.068 49.370 -14.221 1.00 11.37 ? 102 VAL B CG1 1 ATOM 4814 C CG2 . VAL B 1 102 ? 52.964 51.007 -14.085 1.00 11.57 ? 102 VAL B CG2 1 ATOM 4815 N N . LEU B 1 103 ? 54.842 48.657 -14.144 1.00 8.98 ? 103 LEU B N 1 ATOM 4816 C CA . LEU B 1 103 ? 55.535 47.840 -13.153 1.00 9.71 ? 103 LEU B CA 1 ATOM 4817 C C . LEU B 1 103 ? 54.576 47.689 -11.975 1.00 9.66 ? 103 LEU B C 1 ATOM 4818 O O . LEU B 1 103 ? 54.032 48.673 -11.474 1.00 10.99 ? 103 LEU B O 1 ATOM 4819 C CB . LEU B 1 103 ? 56.833 48.514 -12.705 1.00 9.55 ? 103 LEU B CB 1 ATOM 4820 C CG . LEU B 1 103 ? 57.669 47.705 -11.710 1.00 9.55 ? 103 LEU B CG 1 ATOM 4821 C CD1 . LEU B 1 103 ? 58.103 46.390 -12.347 1.00 10.38 ? 103 LEU B CD1 1 ATOM 4822 C CD2 . LEU B 1 103 ? 58.883 48.518 -11.284 1.00 10.12 ? 103 LEU B CD2 1 ATOM 4823 N N . GLY B 1 104 ? 54.372 46.452 -11.540 1.00 8.62 ? 104 GLY B N 1 ATOM 4824 C CA . GLY B 1 104 ? 53.435 46.187 -10.466 1.00 8.29 ? 104 GLY B CA 1 ATOM 4825 C C . GLY B 1 104 ? 52.242 45.492 -11.103 1.00 7.14 ? 104 GLY B C 1 ATOM 4826 O O . GLY B 1 104 ? 51.391 44.920 -10.428 1.00 9.03 ? 104 GLY B O 1 ATOM 4827 N N . GLY B 1 105 ? 52.191 45.549 -12.428 1.00 7.10 ? 105 GLY B N 1 ATOM 4828 C CA . GLY B 1 105 ? 51.116 44.911 -13.161 1.00 7.85 ? 105 GLY B CA 1 ATOM 4829 C C . GLY B 1 105 ? 49.732 45.465 -12.896 1.00 7.68 ? 105 GLY B C 1 ATOM 4830 O O . GLY B 1 105 ? 49.548 46.647 -12.600 1.00 7.71 ? 105 GLY B O 1 ATOM 4831 N N . THR B 1 106 ? 48.743 44.589 -12.988 1.00 7.85 ? 106 THR B N 1 ATOM 4832 C CA . THR B 1 106 ? 47.364 44.993 -12.790 1.00 8.45 ? 106 THR B CA 1 ATOM 4833 C C . THR B 1 106 ? 47.034 45.327 -11.332 1.00 8.34 ? 106 THR B C 1 ATOM 4834 O O . THR B 1 106 ? 45.998 45.929 -11.047 1.00 8.36 ? 106 THR B O 1 ATOM 4835 C CB . THR B 1 106 ? 46.431 43.905 -13.368 1.00 9.25 ? 106 THR B CB 1 ATOM 4836 O OG1 . THR B 1 106 ? 46.761 43.708 -14.750 1.00 7.79 ? 106 THR B OG1 1 ATOM 4837 C CG2 . THR B 1 106 ? 44.973 44.322 -13.281 1.00 7.82 ? 106 THR B CG2 1 ATOM 4838 N N . SER B 1 107 ? 47.921 44.965 -10.407 1.00 8.57 ? 107 SER B N 1 ATOM 4839 C CA . SER B 1 107 ? 47.682 45.282 -9.000 1.00 7.88 ? 107 SER B CA 1 ATOM 4840 C C . SER B 1 107 ? 47.863 46.790 -8.801 1.00 9.38 ? 107 SER B C 1 ATOM 4841 O O . SER B 1 107 ? 47.490 47.336 -7.761 1.00 9.71 ? 107 SER B O 1 ATOM 4842 C CB . SER B 1 107 ? 48.651 44.517 -8.083 1.00 8.44 ? 107 SER B CB 1 ATOM 4843 O OG . SER B 1 107 ? 49.967 45.045 -8.150 1.00 8.16 ? 107 SER B OG 1 ATOM 4844 N N . ILE B 1 108 ? 48.427 47.455 -9.808 1.00 9.43 ? 108 ILE B N 1 ATOM 4845 C CA . ILE B 1 108 ? 48.659 48.901 -9.762 1.00 10.44 ? 108 ILE B CA 1 ATOM 4846 C C . ILE B 1 108 ? 47.457 49.712 -10.259 1.00 10.71 ? 108 ILE B C 1 ATOM 4847 O O . ILE B 1 108 ? 47.387 50.925 -10.044 1.00 11.73 ? 108 ILE B O 1 ATOM 4848 C CB . ILE B 1 108 ? 49.939 49.282 -10.590 1.00 11.56 ? 108 ILE B CB 1 ATOM 4849 C CG1 . ILE B 1 108 ? 51.187 49.111 -9.721 1.00 14.99 ? 108 ILE B CG1 1 ATOM 4850 C CG2 . ILE B 1 108 ? 49.866 50.722 -11.096 1.00 13.40 ? 108 ILE B CG2 1 ATOM 4851 C CD1 . ILE B 1 108 ? 51.337 50.186 -8.644 1.00 15.72 ? 108 ILE B CD1 1 ATOM 4852 N N . ILE B 1 109 ? 46.502 49.049 -10.906 1.00 9.81 ? 109 ILE B N 1 ATOM 4853 C CA . ILE B 1 109 ? 45.328 49.748 -11.425 1.00 9.36 ? 109 ILE B CA 1 ATOM 4854 C C . ILE B 1 109 ? 44.003 49.153 -10.971 1.00 9.39 ? 109 ILE B C 1 ATOM 4855 O O . ILE B 1 109 ? 42.943 49.600 -11.417 1.00 8.90 ? 109 ILE B O 1 ATOM 4856 C CB . ILE B 1 109 ? 45.308 49.765 -12.975 1.00 9.78 ? 109 ILE B CB 1 ATOM 4857 C CG1 . ILE B 1 109 ? 45.199 48.332 -13.515 1.00 10.34 ? 109 ILE B CG1 1 ATOM 4858 C CG2 . ILE B 1 109 ? 46.557 50.455 -13.509 1.00 9.83 ? 109 ILE B CG2 1 ATOM 4859 C CD1 . ILE B 1 109 ? 44.792 48.261 -14.978 1.00 9.36 ? 109 ILE B CD1 1 ATOM 4860 N N . ASN B 1 110 ? 44.048 48.165 -10.080 1.00 7.20 ? 110 ASN B N 1 ATOM 4861 C CA . ASN B 1 110 ? 42.814 47.519 -9.644 1.00 8.32 ? 110 ASN B CA 1 ATOM 4862 C C . ASN B 1 110 ? 42.015 48.235 -8.558 1.00 8.27 ? 110 ASN B C 1 ATOM 4863 O O . ASN B 1 110 ? 42.344 49.359 -8.169 1.00 8.24 ? 110 ASN B O 1 ATOM 4864 C CB . ASN B 1 110 ? 43.085 46.055 -9.247 1.00 8.00 ? 110 ASN B CB 1 ATOM 4865 C CG . ASN B 1 110 ? 43.945 45.912 -8.010 1.00 7.20 ? 110 ASN B CG 1 ATOM 4866 O OD1 . ASN B 1 110 ? 44.045 46.819 -7.193 1.00 8.16 ? 110 ASN B OD1 1 ATOM 4867 N ND2 . ASN B 1 110 ? 44.552 44.737 -7.856 1.00 8.22 ? 110 ASN B ND2 1 ATOM 4868 N N . ALA B 1 111 ? 40.947 47.589 -8.096 1.00 6.73 ? 111 ALA B N 1 ATOM 4869 C CA . ALA B 1 111 ? 40.070 48.168 -7.079 1.00 7.72 ? 111 ALA B CA 1 ATOM 4870 C C . ALA B 1 111 ? 40.534 47.961 -5.635 1.00 7.54 ? 111 ALA B C 1 ATOM 4871 O O . ALA B 1 111 ? 39.800 48.270 -4.691 1.00 9.45 ? 111 ALA B O 1 ATOM 4872 C CB . ALA B 1 111 ? 38.646 47.639 -7.260 1.00 7.31 ? 111 ALA B CB 1 ATOM 4873 N N . GLY B 1 112 ? 41.738 47.421 -5.472 1.00 7.91 ? 112 GLY B N 1 ATOM 4874 C CA . GLY B 1 112 ? 42.313 47.227 -4.148 1.00 7.21 ? 112 GLY B CA 1 ATOM 4875 C C . GLY B 1 112 ? 41.791 46.157 -3.205 1.00 7.49 ? 112 GLY B C 1 ATOM 4876 O O . GLY B 1 112 ? 42.401 45.924 -2.163 1.00 8.18 ? 112 GLY B O 1 ATOM 4877 N N . VAL B 1 113 ? 40.690 45.496 -3.548 1.00 8.16 ? 113 VAL B N 1 ATOM 4878 C CA . VAL B 1 113 ? 40.132 44.473 -2.664 1.00 7.28 ? 113 VAL B CA 1 ATOM 4879 C C . VAL B 1 113 ? 41.087 43.296 -2.479 1.00 7.36 ? 113 VAL B C 1 ATOM 4880 O O . VAL B 1 113 ? 41.569 42.718 -3.455 1.00 7.97 ? 113 VAL B O 1 ATOM 4881 C CB . VAL B 1 113 ? 38.779 43.954 -3.199 1.00 7.63 ? 113 VAL B CB 1 ATOM 4882 C CG1 . VAL B 1 113 ? 38.163 42.976 -2.205 1.00 8.37 ? 113 VAL B CG1 1 ATOM 4883 C CG2 . VAL B 1 113 ? 37.831 45.127 -3.432 1.00 6.31 ? 113 VAL B CG2 1 ATOM 4884 N N . TYR B 1 114 ? 41.362 42.949 -1.222 1.00 7.08 ? 114 TYR B N 1 ATOM 4885 C CA . TYR B 1 114 ? 42.264 41.838 -0.917 1.00 8.11 ? 114 TYR B CA 1 ATOM 4886 C C . TYR B 1 114 ? 41.582 40.714 -0.151 1.00 7.98 ? 114 TYR B C 1 ATOM 4887 O O . TYR B 1 114 ? 40.952 40.948 0.882 1.00 8.25 ? 114 TYR B O 1 ATOM 4888 C CB . TYR B 1 114 ? 43.458 42.318 -0.086 1.00 6.92 ? 114 TYR B CB 1 ATOM 4889 C CG . TYR B 1 114 ? 44.440 41.211 0.252 1.00 7.24 ? 114 TYR B CG 1 ATOM 4890 C CD1 . TYR B 1 114 ? 45.545 40.956 -0.562 1.00 7.71 ? 114 TYR B CD1 1 ATOM 4891 C CD2 . TYR B 1 114 ? 44.252 40.404 1.377 1.00 7.61 ? 114 TYR B CD2 1 ATOM 4892 C CE1 . TYR B 1 114 ? 46.443 39.922 -0.262 1.00 7.75 ? 114 TYR B CE1 1 ATOM 4893 C CE2 . TYR B 1 114 ? 45.137 39.372 1.682 1.00 8.86 ? 114 TYR B CE2 1 ATOM 4894 C CZ . TYR B 1 114 ? 46.230 39.136 0.861 1.00 7.00 ? 114 TYR B CZ 1 ATOM 4895 O OH . TYR B 1 114 ? 47.112 38.124 1.168 1.00 9.03 ? 114 TYR B OH 1 ATOM 4896 N N . ALA B 1 115 ? 41.739 39.491 -0.649 1.00 7.66 ? 115 ALA B N 1 ATOM 4897 C CA . ALA B 1 115 ? 41.163 38.320 -0.006 1.00 7.62 ? 115 ALA B CA 1 ATOM 4898 C C . ALA B 1 115 ? 42.087 37.121 -0.170 1.00 7.79 ? 115 ALA B C 1 ATOM 4899 O O . ALA B 1 115 ? 42.808 37.018 -1.162 1.00 6.86 ? 115 ALA B O 1 ATOM 4900 C CB . ALA B 1 115 ? 39.799 38.005 -0.620 1.00 8.78 ? 115 ALA B CB 1 ATOM 4901 N N . ARG B 1 116 ? 42.095 36.236 0.822 1.00 7.47 ? 116 ARG B N 1 ATOM 4902 C CA . ARG B 1 116 ? 42.886 35.017 0.725 1.00 8.45 ? 116 ARG B CA 1 ATOM 4903 C C . ARG B 1 116 ? 41.987 34.050 -0.032 1.00 9.39 ? 116 ARG B C 1 ATOM 4904 O O . ARG B 1 116 ? 40.765 34.182 -0.001 1.00 9.11 ? 116 ARG B O 1 ATOM 4905 C CB . ARG B 1 116 ? 43.199 34.438 2.108 1.00 8.91 ? 116 ARG B CB 1 ATOM 4906 C CG . ARG B 1 116 ? 44.266 35.189 2.867 1.00 8.90 ? 116 ARG B CG 1 ATOM 4907 C CD . ARG B 1 116 ? 44.631 34.446 4.137 1.00 9.26 ? 116 ARG B CD 1 ATOM 4908 N NE . ARG B 1 116 ? 45.697 35.120 4.870 1.00 10.09 ? 116 ARG B NE 1 ATOM 4909 C CZ . ARG B 1 116 ? 46.311 34.605 5.929 1.00 11.73 ? 116 ARG B CZ 1 ATOM 4910 N NH1 . ARG B 1 116 ? 45.965 33.405 6.379 1.00 10.87 ? 116 ARG B NH1 1 ATOM 4911 N NH2 . ARG B 1 116 ? 47.274 35.289 6.535 1.00 12.61 ? 116 ARG B NH2 1 ATOM 4912 N N . ALA B 1 117 ? 42.586 33.078 -0.707 1.00 8.05 ? 117 ALA B N 1 ATOM 4913 C CA . ALA B 1 117 ? 41.805 32.116 -1.467 1.00 9.55 ? 117 ALA B CA 1 ATOM 4914 C C . ALA B 1 117 ? 40.954 31.190 -0.601 1.00 10.84 ? 117 ALA B C 1 ATOM 4915 O O . ALA B 1 117 ? 41.266 30.931 0.564 1.00 10.67 ? 117 ALA B O 1 ATOM 4916 C CB . ALA B 1 117 ? 42.727 31.289 -2.349 1.00 9.00 ? 117 ALA B CB 1 ATOM 4917 N N . ASN B 1 118 ? 39.866 30.710 -1.197 1.00 11.10 ? 118 ASN B N 1 ATOM 4918 C CA . ASN B 1 118 ? 38.948 29.764 -0.570 1.00 12.07 ? 118 ASN B CA 1 ATOM 4919 C C . ASN B 1 118 ? 39.833 28.604 -0.091 1.00 13.64 ? 118 ASN B C 1 ATOM 4920 O O . ASN B 1 118 ? 40.499 27.961 -0.900 1.00 13.76 ? 118 ASN B O 1 ATOM 4921 C CB . ASN B 1 118 ? 37.961 29.279 -1.638 1.00 11.12 ? 118 ASN B CB 1 ATOM 4922 C CG . ASN B 1 118 ? 36.954 28.277 -1.112 1.00 12.89 ? 118 ASN B CG 1 ATOM 4923 O OD1 . ASN B 1 118 ? 37.238 27.517 -0.187 1.00 14.84 ? 118 ASN B OD1 1 ATOM 4924 N ND2 . ASN B 1 118 ? 35.774 28.262 -1.727 1.00 14.59 ? 118 ASN B ND2 1 ATOM 4925 N N . THR B 1 119 ? 39.852 28.334 1.211 1.00 14.45 ? 119 THR B N 1 ATOM 4926 C CA . THR B 1 119 ? 40.709 27.268 1.731 1.00 15.82 ? 119 THR B CA 1 ATOM 4927 C C . THR B 1 119 ? 40.386 25.863 1.221 1.00 16.74 ? 119 THR B C 1 ATOM 4928 O O . THR B 1 119 ? 41.150 24.929 1.459 1.00 17.89 ? 119 THR B O 1 ATOM 4929 C CB . THR B 1 119 ? 40.705 27.241 3.283 1.00 16.82 ? 119 THR B CB 1 ATOM 4930 O OG1 . THR B 1 119 ? 39.375 27.011 3.761 1.00 18.92 ? 119 THR B OG1 1 ATOM 4931 C CG2 . THR B 1 119 ? 41.222 28.559 3.842 1.00 17.72 ? 119 THR B CG2 1 ATOM 4932 N N . SER B 1 120 ? 39.275 25.713 0.508 1.00 16.62 ? 120 SER B N 1 ATOM 4933 C CA . SER B 1 120 ? 38.880 24.404 -0.010 1.00 19.01 ? 120 SER B CA 1 ATOM 4934 C C . SER B 1 120 ? 39.271 24.149 -1.468 1.00 19.71 ? 120 SER B C 1 ATOM 4935 O O . SER B 1 120 ? 39.049 23.055 -1.987 1.00 21.58 ? 120 SER B O 1 ATOM 4936 C CB . SER B 1 120 ? 37.366 24.222 0.134 1.00 19.35 ? 120 SER B CB 1 ATOM 4937 O OG . SER B 1 120 ? 36.958 24.386 1.480 1.00 21.70 ? 120 SER B OG 1 ATOM 4938 N N . ILE B 1 121 ? 39.865 25.139 -2.127 1.00 19.47 ? 121 ILE B N 1 ATOM 4939 C CA . ILE B 1 121 ? 40.231 24.977 -3.533 1.00 20.03 ? 121 ILE B CA 1 ATOM 4940 C C . ILE B 1 121 ? 41.615 24.398 -3.811 1.00 19.39 ? 121 ILE B C 1 ATOM 4941 O O . ILE B 1 121 ? 41.926 24.059 -4.952 1.00 19.70 ? 121 ILE B O 1 ATOM 4942 C CB . ILE B 1 121 ? 40.096 26.319 -4.308 1.00 20.65 ? 121 ILE B CB 1 ATOM 4943 C CG1 . ILE B 1 121 ? 40.980 27.404 -3.684 1.00 22.12 ? 121 ILE B CG1 1 ATOM 4944 C CG2 . ILE B 1 121 ? 38.647 26.770 -4.305 1.00 20.83 ? 121 ILE B CG2 1 ATOM 4945 C CD1 . ILE B 1 121 ? 42.470 27.236 -3.919 1.00 21.51 ? 121 ILE B CD1 1 ATOM 4946 N N . TYR B 1 122 ? 42.442 24.275 -2.778 1.00 18.57 ? 122 TYR B N 1 ATOM 4947 C CA . TYR B 1 122 ? 43.791 23.755 -2.960 1.00 18.07 ? 122 TYR B CA 1 ATOM 4948 C C . TYR B 1 122 ? 43.859 22.272 -3.323 1.00 20.04 ? 122 TYR B C 1 ATOM 4949 O O . TYR B 1 122 ? 44.691 21.862 -4.129 1.00 19.06 ? 122 TYR B O 1 ATOM 4950 C CB . TYR B 1 122 ? 44.634 24.018 -1.706 1.00 16.30 ? 122 TYR B CB 1 ATOM 4951 C CG . TYR B 1 122 ? 44.795 25.487 -1.367 1.00 13.97 ? 122 TYR B CG 1 ATOM 4952 C CD1 . TYR B 1 122 ? 43.917 26.124 -0.488 1.00 13.26 ? 122 TYR B CD1 1 ATOM 4953 C CD2 . TYR B 1 122 ? 45.824 26.243 -1.932 1.00 11.97 ? 122 TYR B CD2 1 ATOM 4954 C CE1 . TYR B 1 122 ? 44.062 27.481 -0.177 1.00 13.21 ? 122 TYR B CE1 1 ATOM 4955 C CE2 . TYR B 1 122 ? 45.975 27.600 -1.629 1.00 12.66 ? 122 TYR B CE2 1 ATOM 4956 C CZ . TYR B 1 122 ? 45.095 28.208 -0.752 1.00 11.56 ? 122 TYR B CZ 1 ATOM 4957 O OH . TYR B 1 122 ? 45.263 29.538 -0.436 1.00 10.86 ? 122 TYR B OH 1 ATOM 4958 N N . SER B 1 123 ? 42.979 21.471 -2.739 1.00 20.96 ? 123 SER B N 1 ATOM 4959 C CA . SER B 1 123 ? 42.975 20.036 -3.004 1.00 23.79 ? 123 SER B CA 1 ATOM 4960 C C . SER B 1 123 ? 42.669 19.598 -4.437 1.00 24.05 ? 123 SER B C 1 ATOM 4961 O O . SER B 1 123 ? 43.260 18.640 -4.927 1.00 25.41 ? 123 SER B O 1 ATOM 4962 C CB . SER B 1 123 ? 42.014 19.332 -2.043 1.00 24.78 ? 123 SER B CB 1 ATOM 4963 O OG . SER B 1 123 ? 42.530 19.332 -0.721 1.00 28.34 ? 123 SER B OG 1 ATOM 4964 N N . ALA B 1 124 ? 41.760 20.288 -5.114 1.00 24.69 ? 124 ALA B N 1 ATOM 4965 C CA . ALA B 1 124 ? 41.402 19.914 -6.482 1.00 25.07 ? 124 ALA B CA 1 ATOM 4966 C C . ALA B 1 124 ? 42.126 20.726 -7.548 1.00 24.95 ? 124 ALA B C 1 ATOM 4967 O O . ALA B 1 124 ? 41.749 20.703 -8.714 1.00 26.18 ? 124 ALA B O 1 ATOM 4968 C CB . ALA B 1 124 ? 39.890 20.042 -6.669 1.00 25.72 ? 124 ALA B CB 1 ATOM 4969 N N . SER B 1 125 ? 43.173 21.434 -7.148 1.00 22.95 ? 125 SER B N 1 ATOM 4970 C CA . SER B 1 125 ? 43.925 22.282 -8.070 1.00 20.52 ? 125 SER B CA 1 ATOM 4971 C C . SER B 1 125 ? 44.912 21.610 -9.026 1.00 19.30 ? 125 SER B C 1 ATOM 4972 O O . SER B 1 125 ? 45.224 22.164 -10.075 1.00 19.62 ? 125 SER B O 1 ATOM 4973 C CB . SER B 1 125 ? 44.672 23.358 -7.274 1.00 19.72 ? 125 SER B CB 1 ATOM 4974 O OG . SER B 1 125 ? 45.657 22.761 -6.455 1.00 19.49 ? 125 SER B OG 1 ATOM 4975 N N . GLY B 1 126 ? 45.414 20.434 -8.668 1.00 18.15 ? 126 GLY B N 1 ATOM 4976 C CA . GLY B 1 126 ? 46.381 19.763 -9.520 1.00 15.60 ? 126 GLY B CA 1 ATOM 4977 C C . GLY B 1 126 ? 47.779 20.049 -9.014 1.00 15.37 ? 126 GLY B C 1 ATOM 4978 O O . GLY B 1 126 ? 48.781 19.693 -9.634 1.00 14.69 ? 126 GLY B O 1 ATOM 4979 N N . VAL B 1 127 ? 47.827 20.717 -7.868 1.00 14.19 ? 127 VAL B N 1 ATOM 4980 C CA . VAL B 1 127 ? 49.071 21.077 -7.204 1.00 13.75 ? 127 VAL B CA 1 ATOM 4981 C C . VAL B 1 127 ? 48.977 20.599 -5.758 1.00 14.31 ? 127 VAL B C 1 ATOM 4982 O O . VAL B 1 127 ? 47.938 20.748 -5.118 1.00 15.17 ? 127 VAL B O 1 ATOM 4983 C CB . VAL B 1 127 ? 49.286 22.619 -7.200 1.00 12.75 ? 127 VAL B CB 1 ATOM 4984 C CG1 . VAL B 1 127 ? 50.469 22.990 -6.306 1.00 12.42 ? 127 VAL B CG1 1 ATOM 4985 C CG2 . VAL B 1 127 ? 49.523 23.113 -8.622 1.00 11.50 ? 127 VAL B CG2 1 ATOM 4986 N N . ASP B 1 128 ? 50.052 20.006 -5.252 1.00 14.69 ? 128 ASP B N 1 ATOM 4987 C CA . ASP B 1 128 ? 50.075 19.541 -3.869 1.00 16.35 ? 128 ASP B CA 1 ATOM 4988 C C . ASP B 1 128 ? 50.664 20.699 -3.072 1.00 14.04 ? 128 ASP B C 1 ATOM 4989 O O . ASP B 1 128 ? 51.873 20.914 -3.074 1.00 14.82 ? 128 ASP B O 1 ATOM 4990 C CB . ASP B 1 128 ? 50.952 18.294 -3.749 1.00 18.24 ? 128 ASP B CB 1 ATOM 4991 C CG . ASP B 1 128 ? 50.274 17.053 -4.301 1.00 21.14 ? 128 ASP B CG 1 ATOM 4992 O OD1 . ASP B 1 128 ? 50.988 16.129 -4.739 1.00 24.94 ? 128 ASP B OD1 1 ATOM 4993 O OD2 . ASP B 1 128 ? 49.025 16.994 -4.283 1.00 22.68 ? 128 ASP B OD2 1 ATOM 4994 N N . TRP B 1 129 ? 49.796 21.448 -2.400 1.00 15.15 ? 129 TRP B N 1 ATOM 4995 C CA . TRP B 1 129 ? 50.224 22.619 -1.643 1.00 13.87 ? 129 TRP B CA 1 ATOM 4996 C C . TRP B 1 129 ? 50.791 22.396 -0.251 1.00 14.49 ? 129 TRP B C 1 ATOM 4997 O O . TRP B 1 129 ? 50.294 21.575 0.518 1.00 13.81 ? 129 TRP B O 1 ATOM 4998 C CB . TRP B 1 129 ? 49.067 23.617 -1.518 1.00 14.57 ? 129 TRP B CB 1 ATOM 4999 C CG . TRP B 1 129 ? 48.499 24.075 -2.823 1.00 13.72 ? 129 TRP B CG 1 ATOM 5000 C CD1 . TRP B 1 129 ? 47.546 23.446 -3.569 1.00 13.32 ? 129 TRP B CD1 1 ATOM 5001 C CD2 . TRP B 1 129 ? 48.863 25.257 -3.546 1.00 13.05 ? 129 TRP B CD2 1 ATOM 5002 N NE1 . TRP B 1 129 ? 47.292 24.165 -4.714 1.00 13.53 ? 129 TRP B NE1 1 ATOM 5003 C CE2 . TRP B 1 129 ? 48.087 25.281 -4.724 1.00 12.98 ? 129 TRP B CE2 1 ATOM 5004 C CE3 . TRP B 1 129 ? 49.770 26.299 -3.312 1.00 13.43 ? 129 TRP B CE3 1 ATOM 5005 C CZ2 . TRP B 1 129 ? 48.189 26.308 -5.670 1.00 13.23 ? 129 TRP B CZ2 1 ATOM 5006 C CZ3 . TRP B 1 129 ? 49.873 27.323 -4.254 1.00 12.74 ? 129 TRP B CZ3 1 ATOM 5007 C CH2 . TRP B 1 129 ? 49.085 27.317 -5.417 1.00 11.89 ? 129 TRP B CH2 1 ATOM 5008 N N . ASP B 1 130 ? 51.843 23.150 0.053 1.00 13.61 ? 130 ASP B N 1 ATOM 5009 C CA . ASP B 1 130 ? 52.480 23.142 1.365 1.00 13.06 ? 130 ASP B CA 1 ATOM 5010 C C . ASP B 1 130 ? 51.707 24.274 2.038 1.00 13.71 ? 130 ASP B C 1 ATOM 5011 O O . ASP B 1 130 ? 52.055 25.445 1.885 1.00 13.87 ? 130 ASP B O 1 ATOM 5012 C CB . ASP B 1 130 ? 53.959 23.523 1.240 1.00 14.21 ? 130 ASP B CB 1 ATOM 5013 C CG . ASP B 1 130 ? 54.665 23.595 2.583 1.00 16.50 ? 130 ASP B CG 1 ATOM 5014 O OD1 . ASP B 1 130 ? 54.011 23.954 3.584 1.00 17.57 ? 130 ASP B OD1 1 ATOM 5015 O OD2 . ASP B 1 130 ? 55.881 23.307 2.633 1.00 18.55 ? 130 ASP B OD2 1 ATOM 5016 N N . MET B 1 131 ? 50.644 23.931 2.758 1.00 13.72 ? 131 MET B N 1 ATOM 5017 C CA . MET B 1 131 ? 49.814 24.942 3.404 1.00 14.21 ? 131 MET B CA 1 ATOM 5018 C C . MET B 1 131 ? 50.508 25.819 4.433 1.00 13.38 ? 131 MET B C 1 ATOM 5019 O O . MET B 1 131 ? 50.116 26.969 4.633 1.00 12.76 ? 131 MET B O 1 ATOM 5020 C CB . MET B 1 131 ? 48.574 24.291 4.019 1.00 15.93 ? 131 MET B CB 1 ATOM 5021 C CG . MET B 1 131 ? 47.609 23.721 2.981 1.00 19.00 ? 131 MET B CG 1 ATOM 5022 S SD . MET B 1 131 ? 47.243 24.836 1.591 1.00 23.51 ? 131 MET B SD 1 ATOM 5023 C CE . MET B 1 131 ? 46.255 26.049 2.409 1.00 20.96 ? 131 MET B CE 1 ATOM 5024 N N . ASP B 1 132 ? 51.525 25.292 5.102 1.00 12.51 ? 132 ASP B N 1 ATOM 5025 C CA . ASP B 1 132 ? 52.237 26.116 6.061 1.00 13.82 ? 132 ASP B CA 1 ATOM 5026 C C . ASP B 1 132 ? 52.945 27.211 5.273 1.00 12.26 ? 132 ASP B C 1 ATOM 5027 O O . ASP B 1 132 ? 52.961 28.372 5.687 1.00 12.50 ? 132 ASP B O 1 ATOM 5028 C CB . ASP B 1 132 ? 53.251 25.289 6.856 1.00 16.45 ? 132 ASP B CB 1 ATOM 5029 C CG . ASP B 1 132 ? 52.587 24.300 7.789 1.00 19.48 ? 132 ASP B CG 1 ATOM 5030 O OD1 . ASP B 1 132 ? 51.625 24.687 8.480 1.00 20.26 ? 132 ASP B OD1 1 ATOM 5031 O OD2 . ASP B 1 132 ? 53.033 23.136 7.838 1.00 25.99 ? 132 ASP B OD2 1 ATOM 5032 N N . LEU B 1 133 ? 53.512 26.843 4.125 1.00 12.37 ? 133 LEU B N 1 ATOM 5033 C CA . LEU B 1 133 ? 54.207 27.809 3.281 1.00 11.90 ? 133 LEU B CA 1 ATOM 5034 C C . LEU B 1 133 ? 53.209 28.808 2.700 1.00 11.20 ? 133 LEU B C 1 ATOM 5035 O O . LEU B 1 133 ? 53.482 30.005 2.640 1.00 11.06 ? 133 LEU B O 1 ATOM 5036 C CB . LEU B 1 133 ? 54.956 27.097 2.146 1.00 12.73 ? 133 LEU B CB 1 ATOM 5037 C CG . LEU B 1 133 ? 55.689 27.995 1.141 1.00 12.25 ? 133 LEU B CG 1 ATOM 5038 C CD1 . LEU B 1 133 ? 56.667 28.912 1.862 1.00 13.37 ? 133 LEU B CD1 1 ATOM 5039 C CD2 . LEU B 1 133 ? 56.415 27.130 0.119 1.00 13.86 ? 133 LEU B CD2 1 ATOM 5040 N N . VAL B 1 134 ? 52.050 28.310 2.276 1.00 10.50 ? 134 VAL B N 1 ATOM 5041 C CA . VAL B 1 134 ? 51.017 29.174 1.718 1.00 10.36 ? 134 VAL B CA 1 ATOM 5042 C C . VAL B 1 134 ? 50.673 30.299 2.687 1.00 10.74 ? 134 VAL B C 1 ATOM 5043 O O . VAL B 1 134 ? 50.701 31.471 2.317 1.00 9.71 ? 134 VAL B O 1 ATOM 5044 C CB . VAL B 1 134 ? 49.725 28.385 1.403 1.00 10.50 ? 134 VAL B CB 1 ATOM 5045 C CG1 . VAL B 1 134 ? 48.565 29.348 1.170 1.00 10.28 ? 134 VAL B CG1 1 ATOM 5046 C CG2 . VAL B 1 134 ? 49.937 27.516 0.171 1.00 10.68 ? 134 VAL B CG2 1 ATOM 5047 N N . ASN B 1 135 ? 50.362 29.948 3.932 1.00 10.43 ? 135 ASN B N 1 ATOM 5048 C CA . ASN B 1 135 ? 50.015 30.964 4.919 1.00 9.85 ? 135 ASN B CA 1 ATOM 5049 C C . ASN B 1 135 ? 51.186 31.875 5.275 1.00 9.30 ? 135 ASN B C 1 ATOM 5050 O O . ASN B 1 135 ? 51.001 33.075 5.482 1.00 9.61 ? 135 ASN B O 1 ATOM 5051 C CB . ASN B 1 135 ? 49.445 30.310 6.175 1.00 9.21 ? 135 ASN B CB 1 ATOM 5052 C CG . ASN B 1 135 ? 48.037 29.789 5.964 1.00 10.73 ? 135 ASN B CG 1 ATOM 5053 O OD1 . ASN B 1 135 ? 47.446 29.960 4.892 1.00 10.86 ? 135 ASN B OD1 1 ATOM 5054 N ND2 . ASN B 1 135 ? 47.499 29.154 6.998 1.00 11.62 ? 135 ASN B ND2 1 ATOM 5055 N N . GLN B 1 136 ? 52.388 31.313 5.350 1.00 10.29 ? 136 GLN B N 1 ATOM 5056 C CA . GLN B 1 136 ? 53.565 32.121 5.649 1.00 10.22 ? 136 GLN B CA 1 ATOM 5057 C C . GLN B 1 136 ? 53.698 33.168 4.556 1.00 9.88 ? 136 GLN B C 1 ATOM 5058 O O . GLN B 1 136 ? 54.039 34.321 4.817 1.00 9.15 ? 136 GLN B O 1 ATOM 5059 C CB . GLN B 1 136 ? 54.824 31.251 5.671 1.00 12.47 ? 136 GLN B CB 1 ATOM 5060 C CG . GLN B 1 136 ? 55.022 30.465 6.952 1.00 12.95 ? 136 GLN B CG 1 ATOM 5061 C CD . GLN B 1 136 ? 56.002 29.326 6.769 1.00 16.35 ? 136 GLN B CD 1 ATOM 5062 O OE1 . GLN B 1 136 ? 56.894 29.394 5.922 1.00 18.40 ? 136 GLN B OE1 1 ATOM 5063 N NE2 . GLN B 1 136 ? 55.848 28.274 7.566 1.00 17.80 ? 136 GLN B NE2 1 ATOM 5064 N N . THR B 1 137 ? 53.405 32.757 3.325 1.00 9.84 ? 137 THR B N 1 ATOM 5065 C CA . THR B 1 137 ? 53.509 33.653 2.184 1.00 9.12 ? 137 THR B CA 1 ATOM 5066 C C . THR B 1 137 ? 52.427 34.730 2.223 1.00 9.52 ? 137 THR B C 1 ATOM 5067 O O . THR B 1 137 ? 52.708 35.894 1.956 1.00 9.57 ? 137 THR B O 1 ATOM 5068 C CB . THR B 1 137 ? 53.449 32.858 0.865 1.00 8.74 ? 137 THR B CB 1 ATOM 5069 O OG1 . THR B 1 137 ? 54.508 31.890 0.857 1.00 9.89 ? 137 THR B OG1 1 ATOM 5070 C CG2 . THR B 1 137 ? 53.633 33.787 -0.330 1.00 9.32 ? 137 THR B CG2 1 ATOM 5071 N N . TYR B 1 138 ? 51.197 34.354 2.561 1.00 9.26 ? 138 TYR B N 1 ATOM 5072 C CA . TYR B 1 138 ? 50.128 35.345 2.663 1.00 9.19 ? 138 TYR B CA 1 ATOM 5073 C C . TYR B 1 138 ? 50.560 36.407 3.676 1.00 9.45 ? 138 TYR B C 1 ATOM 5074 O O . TYR B 1 138 ? 50.408 37.605 3.434 1.00 9.63 ? 138 TYR B O 1 ATOM 5075 C CB . TYR B 1 138 ? 48.821 34.700 3.137 1.00 8.30 ? 138 TYR B CB 1 ATOM 5076 C CG . TYR B 1 138 ? 47.982 34.051 2.053 1.00 8.78 ? 138 TYR B CG 1 ATOM 5077 C CD1 . TYR B 1 138 ? 47.425 32.785 2.245 1.00 10.25 ? 138 TYR B CD1 1 ATOM 5078 C CD2 . TYR B 1 138 ? 47.703 34.718 0.859 1.00 9.06 ? 138 TYR B CD2 1 ATOM 5079 C CE1 . TYR B 1 138 ? 46.607 32.199 1.275 1.00 10.12 ? 138 TYR B CE1 1 ATOM 5080 C CE2 . TYR B 1 138 ? 46.885 34.144 -0.114 1.00 9.70 ? 138 TYR B CE2 1 ATOM 5081 C CZ . TYR B 1 138 ? 46.341 32.884 0.099 1.00 9.04 ? 138 TYR B CZ 1 ATOM 5082 O OH . TYR B 1 138 ? 45.527 32.312 -0.857 1.00 10.44 ? 138 TYR B OH 1 ATOM 5083 N N . GLU B 1 139 ? 51.102 35.966 4.810 1.00 9.81 ? 139 GLU B N 1 ATOM 5084 C CA . GLU B 1 139 ? 51.557 36.886 5.854 1.00 10.67 ? 139 GLU B CA 1 ATOM 5085 C C . GLU B 1 139 ? 52.650 37.827 5.348 1.00 8.27 ? 139 GLU B C 1 ATOM 5086 O O . GLU B 1 139 ? 52.644 39.020 5.636 1.00 9.73 ? 139 GLU B O 1 ATOM 5087 C CB . GLU B 1 139 ? 52.055 36.084 7.066 1.00 12.44 ? 139 GLU B CB 1 ATOM 5088 C CG . GLU B 1 139 ? 50.938 35.375 7.819 1.00 16.47 ? 139 GLU B CG 1 ATOM 5089 C CD . GLU B 1 139 ? 51.411 34.200 8.653 1.00 20.56 ? 139 GLU B CD 1 ATOM 5090 O OE1 . GLU B 1 139 ? 50.557 33.589 9.328 1.00 23.83 ? 139 GLU B OE1 1 ATOM 5091 O OE2 . GLU B 1 139 ? 52.623 33.889 8.642 1.00 24.70 ? 139 GLU B OE2 1 ATOM 5092 N N . TRP B 1 140 ? 53.585 37.276 4.587 1.00 8.89 ? 140 TRP B N 1 ATOM 5093 C CA . TRP B 1 140 ? 54.691 38.036 4.015 1.00 8.83 ? 140 TRP B CA 1 ATOM 5094 C C . TRP B 1 140 ? 54.141 39.173 3.145 1.00 8.42 ? 140 TRP B C 1 ATOM 5095 O O . TRP B 1 140 ? 54.609 40.318 3.215 1.00 9.95 ? 140 TRP B O 1 ATOM 5096 C CB . TRP B 1 140 ? 55.546 37.071 3.189 1.00 9.61 ? 140 TRP B CB 1 ATOM 5097 C CG . TRP B 1 140 ? 56.793 37.603 2.575 1.00 10.88 ? 140 TRP B CG 1 ATOM 5098 C CD1 . TRP B 1 140 ? 58.054 37.569 3.108 1.00 11.69 ? 140 TRP B CD1 1 ATOM 5099 C CD2 . TRP B 1 140 ? 56.936 38.092 1.239 1.00 10.88 ? 140 TRP B CD2 1 ATOM 5100 N NE1 . TRP B 1 140 ? 58.973 37.989 2.175 1.00 12.41 ? 140 TRP B NE1 1 ATOM 5101 C CE2 . TRP B 1 140 ? 58.313 38.317 1.019 1.00 12.19 ? 140 TRP B CE2 1 ATOM 5102 C CE3 . TRP B 1 140 ? 56.033 38.353 0.200 1.00 9.92 ? 140 TRP B CE3 1 ATOM 5103 C CZ2 . TRP B 1 140 ? 58.810 38.789 -0.201 1.00 12.55 ? 140 TRP B CZ2 1 ATOM 5104 C CZ3 . TRP B 1 140 ? 56.528 38.825 -1.016 1.00 12.30 ? 140 TRP B CZ3 1 ATOM 5105 C CH2 . TRP B 1 140 ? 57.906 39.036 -1.203 1.00 11.57 ? 140 TRP B CH2 1 ATOM 5106 N N . VAL B 1 141 ? 53.139 38.860 2.327 1.00 8.80 ? 141 VAL B N 1 ATOM 5107 C CA . VAL B 1 141 ? 52.523 39.857 1.458 1.00 9.31 ? 141 VAL B CA 1 ATOM 5108 C C . VAL B 1 141 ? 51.707 40.867 2.260 1.00 8.90 ? 141 VAL B C 1 ATOM 5109 O O . VAL B 1 141 ? 51.853 42.079 2.091 1.00 9.61 ? 141 VAL B O 1 ATOM 5110 C CB . VAL B 1 141 ? 51.584 39.192 0.415 1.00 8.98 ? 141 VAL B CB 1 ATOM 5111 C CG1 . VAL B 1 141 ? 50.822 40.257 -0.364 1.00 9.01 ? 141 VAL B CG1 1 ATOM 5112 C CG2 . VAL B 1 141 ? 52.394 38.326 -0.536 1.00 9.12 ? 141 VAL B CG2 1 ATOM 5113 N N . GLU B 1 142 ? 50.853 40.356 3.139 1.00 8.52 ? 142 GLU B N 1 ATOM 5114 C CA . GLU B 1 142 ? 49.987 41.196 3.957 1.00 8.81 ? 142 GLU B CA 1 ATOM 5115 C C . GLU B 1 142 ? 50.729 42.181 4.853 1.00 9.58 ? 142 GLU B C 1 ATOM 5116 O O . GLU B 1 142 ? 50.299 43.324 5.004 1.00 10.19 ? 142 GLU B O 1 ATOM 5117 C CB . GLU B 1 142 ? 49.051 40.308 4.781 1.00 9.47 ? 142 GLU B CB 1 ATOM 5118 C CG . GLU B 1 142 ? 48.053 39.562 3.900 1.00 10.09 ? 142 GLU B CG 1 ATOM 5119 C CD . GLU B 1 142 ? 47.504 38.300 4.537 1.00 11.45 ? 142 GLU B CD 1 ATOM 5120 O OE1 . GLU B 1 142 ? 46.832 37.526 3.817 1.00 9.97 ? 142 GLU B OE1 1 ATOM 5121 O OE2 . GLU B 1 142 ? 47.743 38.077 5.745 1.00 11.05 ? 142 GLU B OE2 1 ATOM 5122 N N . ASP B 1 143 ? 51.843 41.753 5.436 1.00 10.07 ? 143 ASP B N 1 ATOM 5123 C CA . ASP B 1 143 ? 52.611 42.643 6.305 1.00 11.94 ? 143 ASP B CA 1 ATOM 5124 C C . ASP B 1 143 ? 53.258 43.781 5.521 1.00 11.80 ? 143 ASP B C 1 ATOM 5125 O O . ASP B 1 143 ? 53.765 44.742 6.114 1.00 13.19 ? 143 ASP B O 1 ATOM 5126 C CB . ASP B 1 143 ? 53.704 41.869 7.049 1.00 13.88 ? 143 ASP B CB 1 ATOM 5127 C CG . ASP B 1 143 ? 53.147 40.948 8.118 1.00 15.29 ? 143 ASP B CG 1 ATOM 5128 O OD1 . ASP B 1 143 ? 52.011 41.182 8.582 1.00 20.15 ? 143 ASP B OD1 1 ATOM 5129 O OD2 . ASP B 1 143 ? 53.854 39.996 8.506 1.00 19.58 ? 143 ASP B OD2 1 ATOM 5130 N N . THR B 1 144 ? 53.223 43.685 4.194 1.00 9.94 ? 144 THR B N 1 ATOM 5131 C CA . THR B 1 144 ? 53.839 44.697 3.347 1.00 10.73 ? 144 THR B CA 1 ATOM 5132 C C . THR B 1 144 ? 52.881 45.639 2.624 1.00 10.04 ? 144 THR B C 1 ATOM 5133 O O . THR B 1 144 ? 53.134 46.844 2.557 1.00 10.57 ? 144 THR B O 1 ATOM 5134 C CB . THR B 1 144 ? 54.743 44.042 2.280 1.00 11.76 ? 144 THR B CB 1 ATOM 5135 O OG1 . THR B 1 144 ? 55.629 43.109 2.911 1.00 14.32 ? 144 THR B OG1 1 ATOM 5136 C CG2 . THR B 1 144 ? 55.571 45.100 1.554 1.00 12.19 ? 144 THR B CG2 1 ATOM 5137 N N . ILE B 1 145 ? 51.787 45.101 2.085 1.00 8.62 ? 145 ILE B N 1 ATOM 5138 C CA . ILE B 1 145 ? 50.847 45.928 1.327 1.00 8.96 ? 145 ILE B CA 1 ATOM 5139 C C . ILE B 1 145 ? 49.346 45.761 1.587 1.00 8.92 ? 145 ILE B C 1 ATOM 5140 O O . ILE B 1 145 ? 48.535 46.237 0.792 1.00 9.22 ? 145 ILE B O 1 ATOM 5141 C CB . ILE B 1 145 ? 51.067 45.748 -0.201 1.00 7.67 ? 145 ILE B CB 1 ATOM 5142 C CG1 . ILE B 1 145 ? 50.805 44.293 -0.604 1.00 8.33 ? 145 ILE B CG1 1 ATOM 5143 C CG2 . ILE B 1 145 ? 52.490 46.150 -0.574 1.00 11.11 ? 145 ILE B CG2 1 ATOM 5144 C CD1 . ILE B 1 145 ? 50.791 44.066 -2.108 1.00 7.68 ? 145 ILE B CD1 1 ATOM 5145 N N . VAL B 1 146 ? 48.961 45.106 2.677 1.00 8.85 ? 146 VAL B N 1 ATOM 5146 C CA . VAL B 1 146 ? 47.535 44.930 2.954 1.00 8.41 ? 146 VAL B CA 1 ATOM 5147 C C . VAL B 1 146 ? 47.131 45.633 4.249 1.00 10.71 ? 146 VAL B C 1 ATOM 5148 O O . VAL B 1 146 ? 47.819 45.528 5.270 1.00 11.48 ? 146 VAL B O 1 ATOM 5149 C CB . VAL B 1 146 ? 47.157 43.435 3.017 1.00 9.01 ? 146 VAL B CB 1 ATOM 5150 C CG1 . VAL B 1 146 ? 45.650 43.281 3.225 1.00 8.88 ? 146 VAL B CG1 1 ATOM 5151 C CG2 . VAL B 1 146 ? 47.575 42.749 1.724 1.00 9.49 ? 146 VAL B CG2 1 ATOM 5152 N N . TYR B 1 147 ? 46.007 46.345 4.201 1.00 9.81 ? 147 TYR B N 1 ATOM 5153 C CA . TYR B 1 147 ? 45.542 47.111 5.350 1.00 10.66 ? 147 TYR B CA 1 ATOM 5154 C C . TYR B 1 147 ? 44.103 46.871 5.770 1.00 11.44 ? 147 TYR B C 1 ATOM 5155 O O . TYR B 1 147 ? 43.249 46.564 4.947 1.00 11.73 ? 147 TYR B O 1 ATOM 5156 C CB . TYR B 1 147 ? 45.698 48.611 5.056 1.00 11.20 ? 147 TYR B CB 1 ATOM 5157 C CG . TYR B 1 147 ? 47.037 48.957 4.470 1.00 10.44 ? 147 TYR B CG 1 ATOM 5158 C CD1 . TYR B 1 147 ? 47.316 48.707 3.127 1.00 10.62 ? 147 TYR B CD1 1 ATOM 5159 C CD2 . TYR B 1 147 ? 48.066 49.431 5.280 1.00 9.60 ? 147 TYR B CD2 1 ATOM 5160 C CE1 . TYR B 1 147 ? 48.587 48.909 2.611 1.00 10.60 ? 147 TYR B CE1 1 ATOM 5161 C CE2 . TYR B 1 147 ? 49.338 49.637 4.775 1.00 10.13 ? 147 TYR B CE2 1 ATOM 5162 C CZ . TYR B 1 147 ? 49.595 49.371 3.442 1.00 11.30 ? 147 TYR B CZ 1 ATOM 5163 O OH . TYR B 1 147 ? 50.864 49.546 2.948 1.00 12.05 ? 147 TYR B OH 1 ATOM 5164 N N . LYS B 1 148 ? 43.852 47.023 7.067 1.00 11.40 ? 148 LYS B N 1 ATOM 5165 C CA . LYS B 1 148 ? 42.511 46.910 7.622 1.00 12.32 ? 148 LYS B CA 1 ATOM 5166 C C . LYS B 1 148 ? 41.956 48.289 7.303 1.00 12.90 ? 148 LYS B C 1 ATOM 5167 O O . LYS B 1 148 ? 42.491 49.296 7.762 1.00 13.66 ? 148 LYS B O 1 ATOM 5168 C CB . LYS B 1 148 ? 42.580 46.687 9.131 1.00 12.97 ? 148 LYS B CB 1 ATOM 5169 C CG . LYS B 1 148 ? 41.229 46.656 9.833 1.00 13.85 ? 148 LYS B CG 1 ATOM 5170 C CD . LYS B 1 148 ? 41.409 46.262 11.297 1.00 16.40 ? 148 LYS B CD 1 ATOM 5171 C CE . LYS B 1 148 ? 40.156 46.531 12.118 1.00 21.20 ? 148 LYS B CE 1 ATOM 5172 N NZ . LYS B 1 148 ? 38.967 45.782 11.646 1.00 25.00 ? 148 LYS B NZ 1 ATOM 5173 N N . PRO B 1 149 ? 40.873 48.355 6.517 1.00 12.84 ? 149 PRO B N 1 ATOM 5174 C CA . PRO B 1 149 ? 40.263 49.630 6.124 1.00 12.78 ? 149 PRO B CA 1 ATOM 5175 C C . PRO B 1 149 ? 39.573 50.489 7.174 1.00 12.49 ? 149 PRO B C 1 ATOM 5176 O O . PRO B 1 149 ? 39.188 50.015 8.244 1.00 12.80 ? 149 PRO B O 1 ATOM 5177 C CB . PRO B 1 149 ? 39.296 49.210 5.021 1.00 12.70 ? 149 PRO B CB 1 ATOM 5178 C CG . PRO B 1 149 ? 38.797 47.900 5.524 1.00 13.54 ? 149 PRO B CG 1 ATOM 5179 C CD . PRO B 1 149 ? 40.079 47.219 6.008 1.00 13.08 ? 149 PRO B CD 1 ATOM 5180 N N . ASN B 1 150 ? 39.425 51.769 6.837 1.00 14.96 ? 150 ASN B N 1 ATOM 5181 C CA . ASN B 1 150 ? 38.736 52.729 7.695 1.00 15.52 ? 150 ASN B CA 1 ATOM 5182 C C . ASN B 1 150 ? 37.268 52.361 7.563 1.00 16.09 ? 150 ASN B C 1 ATOM 5183 O O . ASN B 1 150 ? 36.875 51.722 6.585 1.00 15.10 ? 150 ASN B O 1 ATOM 5184 C CB . ASN B 1 150 ? 38.892 54.155 7.159 1.00 17.78 ? 150 ASN B CB 1 ATOM 5185 C CG . ASN B 1 150 ? 40.305 54.686 7.266 1.00 18.76 ? 150 ASN B CG 1 ATOM 5186 O OD1 . ASN B 1 150 ? 40.725 55.507 6.451 1.00 23.77 ? 150 ASN B OD1 1 ATOM 5187 N ND2 . ASN B 1 150 ? 41.035 54.246 8.281 1.00 19.05 ? 150 ASN B ND2 1 ATOM 5188 N N . SER B 1 151 ? 36.452 52.750 8.532 1.00 16.36 ? 151 SER B N 1 ATOM 5189 C CA . SER B 1 151 ? 35.029 52.479 8.418 1.00 16.08 ? 151 SER B CA 1 ATOM 5190 C C . SER B 1 151 ? 34.552 53.508 7.395 1.00 14.76 ? 151 SER B C 1 ATOM 5191 O O . SER B 1 151 ? 35.048 54.639 7.369 1.00 14.07 ? 151 SER B O 1 ATOM 5192 C CB . SER B 1 151 ? 34.321 52.693 9.757 1.00 17.90 ? 151 SER B CB 1 ATOM 5193 O OG . SER B 1 151 ? 34.400 54.044 10.166 1.00 22.16 ? 151 SER B OG 1 ATOM 5194 N N . GLN B 1 152 ? 33.617 53.111 6.538 1.00 12.84 ? 152 GLN B N 1 ATOM 5195 C CA . GLN B 1 152 ? 33.078 54.003 5.514 1.00 12.57 ? 152 GLN B CA 1 ATOM 5196 C C . GLN B 1 152 ? 31.563 53.870 5.512 1.00 12.28 ? 152 GLN B C 1 ATOM 5197 O O . GLN B 1 152 ? 31.030 52.762 5.445 1.00 11.19 ? 152 GLN B O 1 ATOM 5198 C CB . GLN B 1 152 ? 33.616 53.630 4.133 1.00 13.03 ? 152 GLN B CB 1 ATOM 5199 C CG . GLN B 1 152 ? 35.126 53.550 4.039 1.00 12.47 ? 152 GLN B CG 1 ATOM 5200 C CD . GLN B 1 152 ? 35.579 53.077 2.675 1.00 12.54 ? 152 GLN B CD 1 ATOM 5201 O OE1 . GLN B 1 152 ? 35.838 53.878 1.777 1.00 10.28 ? 152 GLN B OE1 1 ATOM 5202 N NE2 . GLN B 1 152 ? 35.655 51.764 2.506 1.00 13.18 ? 152 GLN B NE2 1 ATOM 5203 N N . SER B 1 153 ? 30.873 55.004 5.572 1.00 12.46 ? 153 SER B N 1 ATOM 5204 C CA . SER B 1 153 ? 29.417 55.011 5.607 1.00 12.12 ? 153 SER B CA 1 ATOM 5205 C C . SER B 1 153 ? 28.732 54.139 4.562 1.00 11.29 ? 153 SER B C 1 ATOM 5206 O O . SER B 1 153 ? 27.930 53.275 4.913 1.00 12.60 ? 153 SER B O 1 ATOM 5207 C CB . SER B 1 153 ? 28.892 56.442 5.487 1.00 13.02 ? 153 SER B CB 1 ATOM 5208 O OG . SER B 1 153 ? 27.476 56.455 5.554 1.00 13.08 ? 153 SER B OG 1 ATOM 5209 N N . TRP B 1 154 ? 29.032 54.346 3.282 1.00 11.34 ? 154 TRP B N 1 ATOM 5210 C CA . TRP B 1 154 ? 28.365 53.539 2.269 1.00 9.24 ? 154 TRP B CA 1 ATOM 5211 C C . TRP B 1 154 ? 28.660 52.048 2.384 1.00 9.84 ? 154 TRP B C 1 ATOM 5212 O O . TRP B 1 154 ? 27.776 51.222 2.149 1.00 9.15 ? 154 TRP B O 1 ATOM 5213 C CB . TRP B 1 154 ? 28.696 54.013 0.853 1.00 10.03 ? 154 TRP B CB 1 ATOM 5214 C CG . TRP B 1 154 ? 27.876 53.276 -0.153 1.00 10.09 ? 154 TRP B CG 1 ATOM 5215 C CD1 . TRP B 1 154 ? 28.306 52.311 -1.022 1.00 10.66 ? 154 TRP B CD1 1 ATOM 5216 C CD2 . TRP B 1 154 ? 26.455 53.357 -0.316 1.00 10.14 ? 154 TRP B CD2 1 ATOM 5217 N NE1 . TRP B 1 154 ? 27.240 51.785 -1.709 1.00 10.88 ? 154 TRP B NE1 1 ATOM 5218 C CE2 . TRP B 1 154 ? 26.091 52.408 -1.296 1.00 9.65 ? 154 TRP B CE2 1 ATOM 5219 C CE3 . TRP B 1 154 ? 25.452 54.139 0.274 1.00 12.71 ? 154 TRP B CE3 1 ATOM 5220 C CZ2 . TRP B 1 154 ? 24.765 52.218 -1.700 1.00 10.43 ? 154 TRP B CZ2 1 ATOM 5221 C CZ3 . TRP B 1 154 ? 24.132 53.950 -0.129 1.00 11.26 ? 154 TRP B CZ3 1 ATOM 5222 C CH2 . TRP B 1 154 ? 23.802 52.997 -1.107 1.00 12.02 ? 154 TRP B CH2 1 ATOM 5223 N N . GLN B 1 155 ? 29.892 51.692 2.731 1.00 9.83 ? 155 GLN B N 1 ATOM 5224 C CA . GLN B 1 155 ? 30.210 50.277 2.879 1.00 9.99 ? 155 GLN B CA 1 ATOM 5225 C C . GLN B 1 155 ? 29.415 49.713 4.059 1.00 10.27 ? 155 GLN B C 1 ATOM 5226 O O . GLN B 1 155 ? 28.948 48.574 4.011 1.00 9.72 ? 155 GLN B O 1 ATOM 5227 C CB . GLN B 1 155 ? 31.714 50.076 3.093 1.00 9.34 ? 155 GLN B CB 1 ATOM 5228 C CG . GLN B 1 155 ? 32.560 50.436 1.873 1.00 9.87 ? 155 GLN B CG 1 ATOM 5229 C CD . GLN B 1 155 ? 32.188 49.618 0.644 1.00 9.05 ? 155 GLN B CD 1 ATOM 5230 O OE1 . GLN B 1 155 ? 32.260 48.391 0.658 1.00 9.38 ? 155 GLN B OE1 1 ATOM 5231 N NE2 . GLN B 1 155 ? 31.787 50.296 -0.422 1.00 8.03 ? 155 GLN B NE2 1 ATOM 5232 N N . SER B 1 156 ? 29.244 50.512 5.111 1.00 10.37 ? 156 SER B N 1 ATOM 5233 C CA . SER B 1 156 ? 28.480 50.068 6.275 1.00 11.04 ? 156 SER B CA 1 ATOM 5234 C C . SER B 1 156 ? 27.014 49.882 5.900 1.00 10.86 ? 156 SER B C 1 ATOM 5235 O O . SER B 1 156 ? 26.354 48.953 6.371 1.00 10.47 ? 156 SER B O 1 ATOM 5236 C CB . SER B 1 156 ? 28.600 51.078 7.421 1.00 10.11 ? 156 SER B CB 1 ATOM 5237 O OG . SER B 1 156 ? 29.902 51.061 7.979 1.00 12.30 ? 156 SER B OG 1 ATOM 5238 N N . VAL B 1 157 ? 26.501 50.766 5.050 1.00 10.69 ? 157 VAL B N 1 ATOM 5239 C CA . VAL B 1 157 ? 25.120 50.660 4.604 1.00 10.74 ? 157 VAL B CA 1 ATOM 5240 C C . VAL B 1 157 ? 24.976 49.356 3.826 1.00 11.12 ? 157 VAL B C 1 ATOM 5241 O O . VAL B 1 157 ? 24.009 48.613 3.994 1.00 11.08 ? 157 VAL B O 1 ATOM 5242 C CB . VAL B 1 157 ? 24.738 51.842 3.691 1.00 11.88 ? 157 VAL B CB 1 ATOM 5243 C CG1 . VAL B 1 157 ? 23.381 51.597 3.052 1.00 13.04 ? 157 VAL B CG1 1 ATOM 5244 C CG2 . VAL B 1 157 ? 24.716 53.128 4.503 1.00 14.37 ? 157 VAL B CG2 1 ATOM 5245 N N . THR B 1 158 ? 25.960 49.078 2.978 1.00 9.43 ? 158 THR B N 1 ATOM 5246 C CA . THR B 1 158 ? 25.956 47.864 2.179 1.00 8.57 ? 158 THR B CA 1 ATOM 5247 C C . THR B 1 158 ? 25.997 46.637 3.092 1.00 8.53 ? 158 THR B C 1 ATOM 5248 O O . THR B 1 158 ? 25.309 45.648 2.847 1.00 8.74 ? 158 THR B O 1 ATOM 5249 C CB . THR B 1 158 ? 27.159 47.858 1.216 1.00 8.72 ? 158 THR B CB 1 ATOM 5250 O OG1 . THR B 1 158 ? 27.053 48.983 0.332 1.00 9.54 ? 158 THR B OG1 1 ATOM 5251 C CG2 . THR B 1 158 ? 27.189 46.588 0.389 1.00 9.49 ? 158 THR B CG2 1 ATOM 5252 N N . LYS B 1 159 ? 26.802 46.700 4.147 1.00 8.37 ? 159 LYS B N 1 ATOM 5253 C CA . LYS B 1 159 ? 26.894 45.585 5.085 1.00 8.08 ? 159 LYS B CA 1 ATOM 5254 C C . LYS B 1 159 ? 25.529 45.318 5.725 1.00 8.83 ? 159 LYS B C 1 ATOM 5255 O O . LYS B 1 159 ? 25.119 44.165 5.864 1.00 7.80 ? 159 LYS B O 1 ATOM 5256 C CB . LYS B 1 159 ? 27.943 45.887 6.159 1.00 8.60 ? 159 LYS B CB 1 ATOM 5257 C CG . LYS B 1 159 ? 28.008 44.889 7.313 1.00 8.66 ? 159 LYS B CG 1 ATOM 5258 C CD . LYS B 1 159 ? 29.245 45.163 8.172 1.00 8.58 ? 159 LYS B CD 1 ATOM 5259 C CE . LYS B 1 159 ? 29.239 44.360 9.469 1.00 8.32 ? 159 LYS B CE 1 ATOM 5260 N NZ . LYS B 1 159 ? 30.519 44.566 10.213 1.00 9.22 ? 159 LYS B NZ 1 ATOM 5261 N N . THR B 1 160 ? 24.817 46.377 6.104 1.00 8.54 ? 160 THR B N 1 ATOM 5262 C CA . THR B 1 160 ? 23.504 46.184 6.711 1.00 9.03 ? 160 THR B CA 1 ATOM 5263 C C . THR B 1 160 ? 22.547 45.557 5.699 1.00 8.45 ? 160 THR B C 1 ATOM 5264 O O . THR B 1 160 ? 21.730 44.707 6.051 1.00 9.27 ? 160 THR B O 1 ATOM 5265 C CB . THR B 1 160 ? 22.899 47.515 7.243 1.00 10.77 ? 160 THR B CB 1 ATOM 5266 O OG1 . THR B 1 160 ? 22.611 48.400 6.154 1.00 14.96 ? 160 THR B OG1 1 ATOM 5267 C CG2 . THR B 1 160 ? 23.874 48.193 8.194 1.00 9.16 ? 160 THR B CG2 1 ATOM 5268 N N . ALA B 1 161 ? 22.664 45.962 4.436 1.00 7.86 ? 161 ALA B N 1 ATOM 5269 C CA . ALA B 1 161 ? 21.805 45.428 3.380 1.00 8.91 ? 161 ALA B CA 1 ATOM 5270 C C . ALA B 1 161 ? 22.051 43.933 3.180 1.00 9.56 ? 161 ALA B C 1 ATOM 5271 O O . ALA B 1 161 ? 21.108 43.147 3.093 1.00 9.26 ? 161 ALA B O 1 ATOM 5272 C CB . ALA B 1 161 ? 22.054 46.181 2.084 1.00 9.95 ? 161 ALA B CB 1 ATOM 5273 N N . PHE B 1 162 ? 23.322 43.546 3.102 1.00 9.47 ? 162 PHE B N 1 ATOM 5274 C CA . PHE B 1 162 ? 23.687 42.142 2.933 1.00 9.09 ? 162 PHE B CA 1 ATOM 5275 C C . PHE B 1 162 ? 23.158 41.291 4.090 1.00 9.60 ? 162 PHE B C 1 ATOM 5276 O O . PHE B 1 162 ? 22.593 40.221 3.873 1.00 8.59 ? 162 PHE B O 1 ATOM 5277 C CB . PHE B 1 162 ? 25.214 41.991 2.852 1.00 8.43 ? 162 PHE B CB 1 ATOM 5278 C CG . PHE B 1 162 ? 25.783 42.180 1.469 1.00 8.87 ? 162 PHE B CG 1 ATOM 5279 C CD1 . PHE B 1 162 ? 26.917 42.963 1.275 1.00 10.18 ? 162 PHE B CD1 1 ATOM 5280 C CD2 . PHE B 1 162 ? 25.206 41.555 0.365 1.00 11.39 ? 162 PHE B CD2 1 ATOM 5281 C CE1 . PHE B 1 162 ? 27.473 43.123 0.004 1.00 9.98 ? 162 PHE B CE1 1 ATOM 5282 C CE2 . PHE B 1 162 ? 25.756 41.708 -0.913 1.00 9.61 ? 162 PHE B CE2 1 ATOM 5283 C CZ . PHE B 1 162 ? 26.891 42.495 -1.091 1.00 11.04 ? 162 PHE B CZ 1 ATOM 5284 N N . LEU B 1 163 ? 23.342 41.763 5.321 1.00 8.54 ? 163 LEU B N 1 ATOM 5285 C CA . LEU B 1 163 ? 22.871 41.009 6.481 1.00 8.92 ? 163 LEU B CA 1 ATOM 5286 C C . LEU B 1 163 ? 21.346 40.937 6.521 1.00 9.59 ? 163 LEU B C 1 ATOM 5287 O O . LEU B 1 163 ? 20.770 39.924 6.924 1.00 9.31 ? 163 LEU B O 1 ATOM 5288 C CB . LEU B 1 163 ? 23.425 41.629 7.771 1.00 8.07 ? 163 LEU B CB 1 ATOM 5289 C CG . LEU B 1 163 ? 24.951 41.511 7.891 1.00 9.16 ? 163 LEU B CG 1 ATOM 5290 C CD1 . LEU B 1 163 ? 25.438 42.258 9.125 1.00 12.50 ? 163 LEU B CD1 1 ATOM 5291 C CD2 . LEU B 1 163 ? 25.349 40.038 7.960 1.00 10.76 ? 163 LEU B CD2 1 ATOM 5292 N N . GLU B 1 164 ? 20.690 42.006 6.088 1.00 9.84 ? 164 GLU B N 1 ATOM 5293 C CA . GLU B 1 164 ? 19.238 42.019 6.070 1.00 10.59 ? 164 GLU B CA 1 ATOM 5294 C C . GLU B 1 164 ? 18.747 41.036 5.007 1.00 10.35 ? 164 GLU B C 1 ATOM 5295 O O . GLU B 1 164 ? 17.708 40.398 5.172 1.00 11.52 ? 164 GLU B O 1 ATOM 5296 C CB . GLU B 1 164 ? 18.721 43.427 5.765 1.00 10.99 ? 164 GLU B CB 1 ATOM 5297 C CG . GLU B 1 164 ? 17.389 43.740 6.421 1.00 13.21 ? 164 GLU B CG 1 ATOM 5298 C CD . GLU B 1 164 ? 16.828 45.084 6.000 1.00 11.24 ? 164 GLU B CD 1 ATOM 5299 O OE1 . GLU B 1 164 ? 17.541 46.102 6.142 1.00 12.97 ? 164 GLU B OE1 1 ATOM 5300 O OE2 . GLU B 1 164 ? 15.672 45.118 5.529 1.00 14.06 ? 164 GLU B OE2 1 ATOM 5301 N N . ALA B 1 165 ? 19.513 40.903 3.924 1.00 10.65 ? 165 ALA B N 1 ATOM 5302 C CA . ALA B 1 165 ? 19.155 40.007 2.823 1.00 9.77 ? 165 ALA B CA 1 ATOM 5303 C C . ALA B 1 165 ? 19.608 38.554 2.981 1.00 11.21 ? 165 ALA B C 1 ATOM 5304 O O . ALA B 1 165 ? 19.658 37.806 2.005 1.00 11.42 ? 165 ALA B O 1 ATOM 5305 C CB . ALA B 1 165 ? 19.679 40.574 1.504 1.00 8.75 ? 165 ALA B CB 1 ATOM 5306 N N . GLY B 1 166 ? 19.961 38.159 4.200 1.00 9.77 ? 166 GLY B N 1 ATOM 5307 C CA . GLY B 1 166 ? 20.353 36.781 4.441 1.00 8.90 ? 166 GLY B CA 1 ATOM 5308 C C . GLY B 1 166 ? 21.723 36.292 4.004 1.00 8.58 ? 166 GLY B C 1 ATOM 5309 O O . GLY B 1 166 ? 21.937 35.079 3.919 1.00 9.53 ? 166 GLY B O 1 ATOM 5310 N N . VAL B 1 167 ? 22.651 37.197 3.715 1.00 8.61 ? 167 VAL B N 1 ATOM 5311 C CA . VAL B 1 167 ? 23.993 36.769 3.326 1.00 8.88 ? 167 VAL B CA 1 ATOM 5312 C C . VAL B 1 167 ? 24.709 36.545 4.658 1.00 9.27 ? 167 VAL B C 1 ATOM 5313 O O . VAL B 1 167 ? 25.403 37.422 5.173 1.00 9.97 ? 167 VAL B O 1 ATOM 5314 C CB . VAL B 1 167 ? 24.710 37.846 2.486 1.00 10.50 ? 167 VAL B CB 1 ATOM 5315 C CG1 . VAL B 1 167 ? 26.063 37.319 2.009 1.00 9.63 ? 167 VAL B CG1 1 ATOM 5316 C CG2 . VAL B 1 167 ? 23.849 38.218 1.292 1.00 11.94 ? 167 VAL B CG2 1 ATOM 5317 N N . HIS B 1 168 ? 24.515 35.347 5.200 1.00 9.35 ? 168 HIS B N 1 ATOM 5318 C CA . HIS B 1 168 ? 25.049 34.965 6.502 1.00 9.56 ? 168 HIS B CA 1 ATOM 5319 C C . HIS B 1 168 ? 26.099 33.860 6.453 1.00 9.88 ? 168 HIS B C 1 ATOM 5320 O O . HIS B 1 168 ? 26.180 33.102 5.482 1.00 11.23 ? 168 HIS B O 1 ATOM 5321 C CB . HIS B 1 168 ? 23.883 34.530 7.390 1.00 8.90 ? 168 HIS B CB 1 ATOM 5322 C CG . HIS B 1 168 ? 22.824 35.576 7.544 1.00 8.10 ? 168 HIS B CG 1 ATOM 5323 N ND1 . HIS B 1 168 ? 21.544 35.284 7.965 1.00 9.75 ? 168 HIS B ND1 1 ATOM 5324 C CD2 . HIS B 1 168 ? 22.861 36.917 7.357 1.00 9.34 ? 168 HIS B CD2 1 ATOM 5325 C CE1 . HIS B 1 168 ? 20.840 36.399 8.031 1.00 10.30 ? 168 HIS B CE1 1 ATOM 5326 N NE2 . HIS B 1 168 ? 21.616 37.405 7.667 1.00 9.12 ? 168 HIS B NE2 1 ATOM 5327 N N . PRO B 1 169 ? 26.907 33.741 7.519 1.00 10.09 ? 169 PRO B N 1 ATOM 5328 C CA . PRO B 1 169 ? 26.881 34.585 8.721 1.00 8.86 ? 169 PRO B CA 1 ATOM 5329 C C . PRO B 1 169 ? 27.693 35.865 8.543 1.00 10.45 ? 169 PRO B C 1 ATOM 5330 O O . PRO B 1 169 ? 28.154 36.173 7.444 1.00 9.81 ? 169 PRO B O 1 ATOM 5331 C CB . PRO B 1 169 ? 27.504 33.677 9.771 1.00 10.66 ? 169 PRO B CB 1 ATOM 5332 C CG . PRO B 1 169 ? 28.582 32.998 8.975 1.00 8.46 ? 169 PRO B CG 1 ATOM 5333 C CD . PRO B 1 169 ? 27.854 32.624 7.691 1.00 10.23 ? 169 PRO B CD 1 ATOM 5334 N N . ASN B 1 170 ? 27.858 36.606 9.634 1.00 9.21 ? 170 ASN B N 1 ATOM 5335 C CA . ASN B 1 170 ? 28.664 37.825 9.622 1.00 10.24 ? 170 ASN B CA 1 ATOM 5336 C C . ASN B 1 170 ? 30.035 37.405 10.142 1.00 11.62 ? 170 ASN B C 1 ATOM 5337 O O . ASN B 1 170 ? 30.127 36.707 11.151 1.00 13.40 ? 170 ASN B O 1 ATOM 5338 C CB . ASN B 1 170 ? 28.056 38.891 10.540 1.00 9.91 ? 170 ASN B CB 1 ATOM 5339 C CG . ASN B 1 170 ? 28.978 40.081 10.741 1.00 10.20 ? 170 ASN B CG 1 ATOM 5340 O OD1 . ASN B 1 170 ? 29.819 40.379 9.894 1.00 9.77 ? 170 ASN B OD1 1 ATOM 5341 N ND2 . ASN B 1 170 ? 28.816 40.772 11.860 1.00 10.22 ? 170 ASN B ND2 1 ATOM 5342 N N . HIS B 1 171 ? 31.096 37.815 9.450 1.00 10.27 ? 171 HIS B N 1 ATOM 5343 C CA . HIS B 1 171 ? 32.457 37.452 9.846 1.00 11.28 ? 171 HIS B CA 1 ATOM 5344 C C . HIS B 1 171 ? 33.246 38.618 10.431 1.00 12.11 ? 171 HIS B C 1 ATOM 5345 O O . HIS B 1 171 ? 34.428 38.466 10.746 1.00 12.55 ? 171 HIS B O 1 ATOM 5346 C CB . HIS B 1 171 ? 33.221 36.904 8.637 1.00 11.73 ? 171 HIS B CB 1 ATOM 5347 C CG . HIS B 1 171 ? 32.639 35.648 8.073 1.00 10.60 ? 171 HIS B CG 1 ATOM 5348 N ND1 . HIS B 1 171 ? 32.843 34.411 8.646 1.00 11.58 ? 171 HIS B ND1 1 ATOM 5349 C CD2 . HIS B 1 171 ? 31.839 35.439 7.001 1.00 11.43 ? 171 HIS B CD2 1 ATOM 5350 C CE1 . HIS B 1 171 ? 32.193 33.495 7.952 1.00 12.71 ? 171 HIS B CE1 1 ATOM 5351 N NE2 . HIS B 1 171 ? 31.575 34.093 6.949 1.00 10.53 ? 171 HIS B NE2 1 ATOM 5352 N N . GLY B 1 172 ? 32.598 39.770 10.584 1.00 10.35 ? 172 GLY B N 1 ATOM 5353 C CA . GLY B 1 172 ? 33.289 40.937 11.106 1.00 10.84 ? 172 GLY B CA 1 ATOM 5354 C C . GLY B 1 172 ? 34.394 41.281 10.128 1.00 9.71 ? 172 GLY B C 1 ATOM 5355 O O . GLY B 1 172 ? 34.153 41.312 8.923 1.00 10.21 ? 172 GLY B O 1 ATOM 5356 N N . PHE B 1 173 ? 35.595 41.557 10.626 1.00 9.02 ? 173 PHE B N 1 ATOM 5357 C CA . PHE B 1 173 ? 36.715 41.840 9.736 1.00 8.33 ? 173 PHE B CA 1 ATOM 5358 C C . PHE B 1 173 ? 37.486 40.543 9.550 1.00 9.48 ? 173 PHE B C 1 ATOM 5359 O O . PHE B 1 173 ? 37.951 39.943 10.523 1.00 10.16 ? 173 PHE B O 1 ATOM 5360 C CB . PHE B 1 173 ? 37.664 42.886 10.320 1.00 8.82 ? 173 PHE B CB 1 ATOM 5361 C CG . PHE B 1 173 ? 38.919 43.067 9.504 1.00 8.08 ? 173 PHE B CG 1 ATOM 5362 C CD1 . PHE B 1 173 ? 38.857 43.608 8.223 1.00 8.97 ? 173 PHE B CD1 1 ATOM 5363 C CD2 . PHE B 1 173 ? 40.151 42.648 9.993 1.00 10.06 ? 173 PHE B CD2 1 ATOM 5364 C CE1 . PHE B 1 173 ? 40.007 43.726 7.436 1.00 9.40 ? 173 PHE B CE1 1 ATOM 5365 C CE2 . PHE B 1 173 ? 41.306 42.760 9.218 1.00 10.93 ? 173 PHE B CE2 1 ATOM 5366 C CZ . PHE B 1 173 ? 41.235 43.299 7.936 1.00 10.10 ? 173 PHE B CZ 1 ATOM 5367 N N . SER B 1 174 ? 37.632 40.119 8.300 1.00 8.15 ? 174 SER B N 1 ATOM 5368 C CA . SER B 1 174 ? 38.337 38.878 7.999 1.00 7.80 ? 174 SER B CA 1 ATOM 5369 C C . SER B 1 174 ? 38.834 38.880 6.563 1.00 8.91 ? 174 SER B C 1 ATOM 5370 O O . SER B 1 174 ? 38.150 39.366 5.667 1.00 9.66 ? 174 SER B O 1 ATOM 5371 C CB . SER B 1 174 ? 37.406 37.684 8.214 1.00 9.39 ? 174 SER B CB 1 ATOM 5372 O OG . SER B 1 174 ? 38.047 36.472 7.860 1.00 12.41 ? 174 SER B OG 1 ATOM 5373 N N . LEU B 1 175 ? 40.024 38.325 6.353 1.00 9.10 ? 175 LEU B N 1 ATOM 5374 C CA . LEU B 1 175 ? 40.621 38.266 5.024 1.00 8.40 ? 175 LEU B CA 1 ATOM 5375 C C . LEU B 1 175 ? 40.187 37.036 4.232 1.00 9.09 ? 175 LEU B C 1 ATOM 5376 O O . LEU B 1 175 ? 40.367 36.978 3.016 1.00 9.90 ? 175 LEU B O 1 ATOM 5377 C CB . LEU B 1 175 ? 42.146 38.244 5.140 1.00 8.86 ? 175 LEU B CB 1 ATOM 5378 C CG . LEU B 1 175 ? 42.843 39.383 5.884 1.00 9.94 ? 175 LEU B CG 1 ATOM 5379 C CD1 . LEU B 1 175 ? 44.342 39.134 5.881 1.00 11.16 ? 175 LEU B CD1 1 ATOM 5380 C CD2 . LEU B 1 175 ? 42.520 40.708 5.222 1.00 10.15 ? 175 LEU B CD2 1 ATOM 5381 N N . ASP B 1 176 ? 39.614 36.059 4.922 1.00 8.14 ? 176 ASP B N 1 ATOM 5382 C CA . ASP B 1 176 ? 39.216 34.810 4.286 1.00 8.28 ? 176 ASP B CA 1 ATOM 5383 C C . ASP B 1 176 ? 37.936 34.783 3.472 1.00 7.97 ? 176 ASP B C 1 ATOM 5384 O O . ASP B 1 176 ? 36.899 35.309 3.882 1.00 9.37 ? 176 ASP B O 1 ATOM 5385 C CB . ASP B 1 176 ? 39.161 33.705 5.336 1.00 8.98 ? 176 ASP B CB 1 ATOM 5386 C CG . ASP B 1 176 ? 40.527 33.354 5.868 1.00 11.22 ? 176 ASP B CG 1 ATOM 5387 O OD1 . ASP B 1 176 ? 41.374 32.914 5.063 1.00 12.51 ? 176 ASP B OD1 1 ATOM 5388 O OD2 . ASP B 1 176 ? 40.755 33.519 7.083 1.00 13.50 ? 176 ASP B OD2 1 ATOM 5389 N N . HIS B 1 177 ? 38.028 34.139 2.313 1.00 8.77 ? 177 HIS B N 1 ATOM 5390 C CA . HIS B 1 177 ? 36.892 33.987 1.416 1.00 9.43 ? 177 HIS B CA 1 ATOM 5391 C C . HIS B 1 177 ? 35.973 32.916 1.999 1.00 9.08 ? 177 HIS B C 1 ATOM 5392 O O . HIS B 1 177 ? 36.231 31.718 1.855 1.00 11.88 ? 177 HIS B O 1 ATOM 5393 C CB . HIS B 1 177 ? 37.366 33.545 0.029 1.00 8.49 ? 177 HIS B CB 1 ATOM 5394 C CG . HIS B 1 177 ? 36.247 33.274 -0.929 1.00 9.01 ? 177 HIS B CG 1 ATOM 5395 N ND1 . HIS B 1 177 ? 35.708 34.247 -1.740 1.00 8.88 ? 177 HIS B ND1 1 ATOM 5396 C CD2 . HIS B 1 177 ? 35.532 32.147 -1.164 1.00 9.81 ? 177 HIS B CD2 1 ATOM 5397 C CE1 . HIS B 1 177 ? 34.706 33.733 -2.435 1.00 7.53 ? 177 HIS B CE1 1 ATOM 5398 N NE2 . HIS B 1 177 ? 34.579 32.462 -2.104 1.00 8.70 ? 177 HIS B NE2 1 ATOM 5399 N N . GLU B 1 178 ? 34.908 33.350 2.664 1.00 9.34 ? 178 GLU B N 1 ATOM 5400 C CA . GLU B 1 178 ? 33.946 32.434 3.260 1.00 9.25 ? 178 GLU B CA 1 ATOM 5401 C C . GLU B 1 178 ? 32.534 32.925 2.980 1.00 8.58 ? 178 GLU B C 1 ATOM 5402 O O . GLU B 1 178 ? 32.295 34.128 2.865 1.00 9.70 ? 178 GLU B O 1 ATOM 5403 C CB . GLU B 1 178 ? 34.123 32.357 4.780 1.00 11.13 ? 178 GLU B CB 1 ATOM 5404 C CG . GLU B 1 178 ? 35.489 31.919 5.257 1.00 13.02 ? 178 GLU B CG 1 ATOM 5405 C CD . GLU B 1 178 ? 35.533 31.782 6.769 1.00 13.20 ? 178 GLU B CD 1 ATOM 5406 O OE1 . GLU B 1 178 ? 35.081 30.741 7.289 1.00 16.61 ? 178 GLU B OE1 1 ATOM 5407 O OE2 . GLU B 1 178 ? 36.000 32.725 7.440 1.00 14.12 ? 178 GLU B OE2 1 ATOM 5408 N N . GLU B 1 179 ? 31.602 31.987 2.887 1.00 8.50 ? 179 GLU B N 1 ATOM 5409 C CA . GLU B 1 179 ? 30.206 32.332 2.658 1.00 8.50 ? 179 GLU B CA 1 ATOM 5410 C C . GLU B 1 179 ? 29.736 33.251 3.780 1.00 9.50 ? 179 GLU B C 1 ATOM 5411 O O . GLU B 1 179 ? 29.995 32.992 4.958 1.00 9.20 ? 179 GLU B O 1 ATOM 5412 C CB . GLU B 1 179 ? 29.352 31.060 2.620 1.00 9.59 ? 179 GLU B CB 1 ATOM 5413 C CG . GLU B 1 179 ? 27.855 31.313 2.586 1.00 15.99 ? 179 GLU B CG 1 ATOM 5414 C CD . GLU B 1 179 ? 27.052 30.033 2.517 1.00 19.18 ? 179 GLU B CD 1 ATOM 5415 O OE1 . GLU B 1 179 ? 27.616 28.960 2.824 1.00 23.10 ? 179 GLU B OE1 1 ATOM 5416 O OE2 . GLU B 1 179 ? 25.854 30.104 2.174 1.00 20.77 ? 179 GLU B OE2 1 ATOM 5417 N N . GLY B 1 180 ? 29.050 34.326 3.409 1.00 8.24 ? 180 GLY B N 1 ATOM 5418 C CA . GLY B 1 180 ? 28.562 35.268 4.397 1.00 9.10 ? 180 GLY B CA 1 ATOM 5419 C C . GLY B 1 180 ? 29.027 36.679 4.097 1.00 7.34 ? 180 GLY B C 1 ATOM 5420 O O . GLY B 1 180 ? 29.578 36.949 3.029 1.00 7.86 ? 180 GLY B O 1 ATOM 5421 N N . THR B 1 181 ? 28.810 37.581 5.048 1.00 7.99 ? 181 THR B N 1 ATOM 5422 C CA . THR B 1 181 ? 29.195 38.975 4.886 1.00 7.89 ? 181 THR B CA 1 ATOM 5423 C C . THR B 1 181 ? 30.383 39.315 5.765 1.00 8.18 ? 181 THR B C 1 ATOM 5424 O O . THR B 1 181 ? 30.486 38.836 6.896 1.00 8.04 ? 181 THR B O 1 ATOM 5425 C CB . THR B 1 181 ? 28.031 39.904 5.260 1.00 8.56 ? 181 THR B CB 1 ATOM 5426 O OG1 . THR B 1 181 ? 26.900 39.608 4.429 1.00 8.48 ? 181 THR B OG1 1 ATOM 5427 C CG2 . THR B 1 181 ? 28.432 41.365 5.080 1.00 10.07 ? 181 THR B CG2 1 ATOM 5428 N N . ARG B 1 182 ? 31.278 40.149 5.245 1.00 8.80 ? 182 ARG B N 1 ATOM 5429 C CA . ARG B 1 182 ? 32.454 40.549 6.003 1.00 7.22 ? 182 ARG B CA 1 ATOM 5430 C C . ARG B 1 182 ? 33.092 41.804 5.432 1.00 8.47 ? 182 ARG B C 1 ATOM 5431 O O . ARG B 1 182 ? 32.758 42.245 4.332 1.00 8.73 ? 182 ARG B O 1 ATOM 5432 C CB . ARG B 1 182 ? 33.502 39.427 5.987 1.00 8.01 ? 182 ARG B CB 1 ATOM 5433 C CG . ARG B 1 182 ? 34.334 39.343 4.693 1.00 8.80 ? 182 ARG B CG 1 ATOM 5434 C CD . ARG B 1 182 ? 35.332 38.192 4.760 1.00 6.69 ? 182 ARG B CD 1 ATOM 5435 N NE . ARG B 1 182 ? 36.384 38.259 3.745 1.00 6.36 ? 182 ARG B NE 1 ATOM 5436 C CZ . ARG B 1 182 ? 36.249 37.887 2.475 1.00 6.75 ? 182 ARG B CZ 1 ATOM 5437 N NH1 . ARG B 1 182 ? 35.095 37.415 2.030 1.00 7.14 ? 182 ARG B NH1 1 ATOM 5438 N NH2 . ARG B 1 182 ? 37.287 37.968 1.649 1.00 7.07 ? 182 ARG B NH2 1 ATOM 5439 N N . ILE B 1 183 ? 33.995 42.387 6.212 1.00 7.70 ? 183 ILE B N 1 ATOM 5440 C CA . ILE B 1 183 ? 34.772 43.536 5.776 1.00 7.28 ? 183 ILE B CA 1 ATOM 5441 C C . ILE B 1 183 ? 36.128 42.874 5.555 1.00 7.61 ? 183 ILE B C 1 ATOM 5442 O O . ILE B 1 183 ? 36.655 42.231 6.464 1.00 7.10 ? 183 ILE B O 1 ATOM 5443 C CB . ILE B 1 183 ? 34.912 44.605 6.880 1.00 8.15 ? 183 ILE B CB 1 ATOM 5444 C CG1 . ILE B 1 183 ? 33.554 45.255 7.153 1.00 9.32 ? 183 ILE B CG1 1 ATOM 5445 C CG2 . ILE B 1 183 ? 35.936 45.659 6.457 1.00 8.18 ? 183 ILE B CG2 1 ATOM 5446 C CD1 . ILE B 1 183 ? 33.570 46.258 8.295 1.00 12.05 ? 183 ILE B CD1 1 ATOM 5447 N N . THR B 1 184 ? 36.679 42.998 4.352 1.00 5.69 ? 184 THR B N 1 ATOM 5448 C CA . THR B 1 184 ? 37.964 42.377 4.054 1.00 8.06 ? 184 THR B CA 1 ATOM 5449 C C . THR B 1 184 ? 39.086 43.413 3.967 1.00 7.44 ? 184 THR B C 1 ATOM 5450 O O . THR B 1 184 ? 38.856 44.604 4.169 1.00 9.89 ? 184 THR B O 1 ATOM 5451 C CB . THR B 1 184 ? 37.879 41.551 2.739 1.00 7.20 ? 184 THR B CB 1 ATOM 5452 O OG1 . THR B 1 184 ? 39.006 40.674 2.658 1.00 9.49 ? 184 THR B OG1 1 ATOM 5453 C CG2 . THR B 1 184 ? 37.866 42.462 1.514 1.00 7.91 ? 184 THR B CG2 1 ATOM 5454 N N . GLY B 1 185 ? 40.303 42.957 3.688 1.00 9.11 ? 185 GLY B N 1 ATOM 5455 C CA . GLY B 1 185 ? 41.426 43.875 3.595 1.00 8.72 ? 185 GLY B CA 1 ATOM 5456 C C . GLY B 1 185 ? 41.499 44.599 2.263 1.00 8.63 ? 185 GLY B C 1 ATOM 5457 O O . GLY B 1 185 ? 40.775 44.266 1.325 1.00 8.80 ? 185 GLY B O 1 ATOM 5458 N N . SER B 1 186 ? 42.370 45.599 2.183 1.00 8.89 ? 186 SER B N 1 ATOM 5459 C CA . SER B 1 186 ? 42.545 46.371 0.957 1.00 8.42 ? 186 SER B CA 1 ATOM 5460 C C . SER B 1 186 ? 44.012 46.735 0.746 1.00 8.22 ? 186 SER B C 1 ATOM 5461 O O . SER B 1 186 ? 44.775 46.840 1.710 1.00 8.28 ? 186 SER B O 1 ATOM 5462 C CB . SER B 1 186 ? 41.702 47.651 1.028 1.00 9.08 ? 186 SER B CB 1 ATOM 5463 O OG . SER B 1 186 ? 41.908 48.474 -0.108 1.00 9.89 ? 186 SER B OG 1 ATOM 5464 N N . THR B 1 187 ? 44.412 46.907 -0.510 1.00 8.34 ? 187 THR B N 1 ATOM 5465 C CA . THR B 1 187 ? 45.782 47.293 -0.805 1.00 8.71 ? 187 THR B CA 1 ATOM 5466 C C . THR B 1 187 ? 45.892 48.818 -0.834 1.00 9.71 ? 187 THR B C 1 ATOM 5467 O O . THR B 1 187 ? 46.944 49.379 -1.141 1.00 9.24 ? 187 THR B O 1 ATOM 5468 C CB . THR B 1 187 ? 46.301 46.659 -2.121 1.00 8.06 ? 187 THR B CB 1 ATOM 5469 O OG1 . THR B 1 187 ? 45.300 46.740 -3.142 1.00 8.99 ? 187 THR B OG1 1 ATOM 5470 C CG2 . THR B 1 187 ? 46.666 45.200 -1.884 1.00 8.92 ? 187 THR B CG2 1 ATOM 5471 N N . PHE B 1 188 ? 44.779 49.479 -0.524 1.00 10.65 ? 188 PHE B N 1 ATOM 5472 C CA . PHE B 1 188 ? 44.751 50.939 -0.410 1.00 10.80 ? 188 PHE B CA 1 ATOM 5473 C C . PHE B 1 188 ? 44.862 51.141 1.098 1.00 10.17 ? 188 PHE B C 1 ATOM 5474 O O . PHE B 1 188 ? 44.127 50.496 1.850 1.00 11.41 ? 188 PHE B O 1 ATOM 5475 C CB . PHE B 1 188 ? 43.409 51.527 -0.857 1.00 10.97 ? 188 PHE B CB 1 ATOM 5476 C CG . PHE B 1 188 ? 43.203 51.537 -2.338 1.00 9.91 ? 188 PHE B CG 1 ATOM 5477 C CD1 . PHE B 1 188 ? 42.116 50.876 -2.901 1.00 10.27 ? 188 PHE B CD1 1 ATOM 5478 C CD2 . PHE B 1 188 ? 44.078 52.224 -3.176 1.00 9.86 ? 188 PHE B CD2 1 ATOM 5479 C CE1 . PHE B 1 188 ? 41.901 50.898 -4.275 1.00 10.11 ? 188 PHE B CE1 1 ATOM 5480 C CE2 . PHE B 1 188 ? 43.869 52.251 -4.553 1.00 11.19 ? 188 PHE B CE2 1 ATOM 5481 C CZ . PHE B 1 188 ? 42.777 51.585 -5.101 1.00 10.78 ? 188 PHE B CZ 1 ATOM 5482 N N . ASP B 1 189 ? 45.766 52.004 1.561 1.00 10.93 ? 189 ASP B N 1 ATOM 5483 C CA . ASP B 1 189 ? 45.860 52.206 2.999 1.00 10.67 ? 189 ASP B CA 1 ATOM 5484 C C . ASP B 1 189 ? 44.840 53.228 3.497 1.00 11.58 ? 189 ASP B C 1 ATOM 5485 O O . ASP B 1 189 ? 44.047 53.765 2.727 1.00 11.00 ? 189 ASP B O 1 ATOM 5486 C CB . ASP B 1 189 ? 47.292 52.574 3.448 1.00 11.87 ? 189 ASP B CB 1 ATOM 5487 C CG . ASP B 1 189 ? 47.756 53.939 2.962 1.00 12.45 ? 189 ASP B CG 1 ATOM 5488 O OD1 . ASP B 1 189 ? 46.918 54.829 2.720 1.00 11.92 ? 189 ASP B OD1 1 ATOM 5489 O OD2 . ASP B 1 189 ? 48.990 54.123 2.853 1.00 13.89 ? 189 ASP B OD2 1 ATOM 5490 N N . ASN B 1 190 ? 44.866 53.492 4.794 1.00 12.08 ? 190 ASN B N 1 ATOM 5491 C CA . ASN B 1 190 ? 43.903 54.390 5.409 1.00 12.98 ? 190 ASN B CA 1 ATOM 5492 C C . ASN B 1 190 ? 43.962 55.865 5.019 1.00 13.14 ? 190 ASN B C 1 ATOM 5493 O O . ASN B 1 190 ? 43.100 56.651 5.419 1.00 15.01 ? 190 ASN B O 1 ATOM 5494 C CB . ASN B 1 190 ? 43.989 54.200 6.917 1.00 13.81 ? 190 ASN B CB 1 ATOM 5495 C CG . ASN B 1 190 ? 43.827 52.745 7.310 1.00 15.35 ? 190 ASN B CG 1 ATOM 5496 O OD1 . ASN B 1 190 ? 42.734 52.299 7.645 1.00 17.57 ? 190 ASN B OD1 1 ATOM 5497 N ND2 . ASN B 1 190 ? 44.914 51.989 7.237 1.00 19.10 ? 190 ASN B ND2 1 ATOM 5498 N N . LYS B 1 191 ? 44.966 56.247 4.239 1.00 12.90 ? 191 LYS B N 1 ATOM 5499 C CA . LYS B 1 191 ? 45.075 57.625 3.770 1.00 14.56 ? 191 LYS B CA 1 ATOM 5500 C C . LYS B 1 191 ? 44.748 57.650 2.280 1.00 14.89 ? 191 LYS B C 1 ATOM 5501 O O . LYS B 1 191 ? 44.785 58.699 1.639 1.00 16.13 ? 191 LYS B O 1 ATOM 5502 C CB . LYS B 1 191 ? 46.479 58.185 4.019 1.00 15.10 ? 191 LYS B CB 1 ATOM 5503 C CG . LYS B 1 191 ? 46.798 58.360 5.495 1.00 20.25 ? 191 LYS B CG 1 ATOM 5504 C CD . LYS B 1 191 ? 48.162 58.989 5.709 1.00 22.72 ? 191 LYS B CD 1 ATOM 5505 C CE . LYS B 1 191 ? 48.477 59.118 7.194 1.00 26.85 ? 191 LYS B CE 1 ATOM 5506 N NZ . LYS B 1 191 ? 49.794 59.774 7.440 1.00 29.98 ? 191 LYS B NZ 1 ATOM 5507 N N . GLY B 1 192 ? 44.426 56.480 1.738 1.00 14.04 ? 192 GLY B N 1 ATOM 5508 C CA . GLY B 1 192 ? 44.075 56.384 0.333 1.00 14.10 ? 192 GLY B CA 1 ATOM 5509 C C . GLY B 1 192 ? 45.241 56.070 -0.582 1.00 13.84 ? 192 GLY B C 1 ATOM 5510 O O . GLY B 1 192 ? 45.067 55.980 -1.794 1.00 14.84 ? 192 GLY B O 1 ATOM 5511 N N . THR B 1 193 ? 46.431 55.906 -0.015 1.00 12.95 ? 193 THR B N 1 ATOM 5512 C CA . THR B 1 193 ? 47.603 55.598 -0.820 1.00 12.77 ? 193 THR B CA 1 ATOM 5513 C C . THR B 1 193 ? 47.535 54.161 -1.317 1.00 12.29 ? 193 THR B C 1 ATOM 5514 O O . THR B 1 193 ? 47.266 53.247 -0.540 1.00 11.57 ? 193 THR B O 1 ATOM 5515 C CB . THR B 1 193 ? 48.895 55.764 -0.004 1.00 13.38 ? 193 THR B CB 1 ATOM 5516 O OG1 . THR B 1 193 ? 48.989 57.113 0.472 1.00 15.96 ? 193 THR B OG1 1 ATOM 5517 C CG2 . THR B 1 193 ? 50.108 55.447 -0.868 1.00 15.24 ? 193 THR B CG2 1 ATOM 5518 N N . ARG B 1 194 ? 47.771 53.963 -2.610 1.00 10.41 ? 194 ARG B N 1 ATOM 5519 C CA . ARG B 1 194 ? 47.760 52.617 -3.159 1.00 10.43 ? 194 ARG B CA 1 ATOM 5520 C C . ARG B 1 194 ? 49.095 51.937 -2.956 1.00 10.18 ? 194 ARG B C 1 ATOM 5521 O O . ARG B 1 194 ? 50.152 52.531 -3.181 1.00 10.42 ? 194 ARG B O 1 ATOM 5522 C CB . ARG B 1 194 ? 47.462 52.615 -4.661 1.00 9.48 ? 194 ARG B CB 1 ATOM 5523 C CG . ARG B 1 194 ? 47.334 51.194 -5.219 1.00 10.41 ? 194 ARG B CG 1 ATOM 5524 C CD . ARG B 1 194 ? 47.465 51.169 -6.731 1.00 10.57 ? 194 ARG B CD 1 ATOM 5525 N NE . ARG B 1 194 ? 46.287 51.668 -7.434 1.00 9.84 ? 194 ARG B NE 1 ATOM 5526 C CZ . ARG B 1 194 ? 45.168 50.977 -7.613 1.00 9.31 ? 194 ARG B CZ 1 ATOM 5527 N NH1 . ARG B 1 194 ? 45.070 49.751 -7.129 1.00 9.89 ? 194 ARG B NH1 1 ATOM 5528 N NH2 . ARG B 1 194 ? 44.166 51.497 -8.307 1.00 8.98 ? 194 ARG B NH2 1 ATOM 5529 N N . HIS B 1 195 ? 49.031 50.684 -2.533 1.00 9.30 ? 195 HIS B N 1 ATOM 5530 C CA . HIS B 1 195 ? 50.211 49.867 -2.347 1.00 9.22 ? 195 HIS B CA 1 ATOM 5531 C C . HIS B 1 195 ? 50.001 48.708 -3.313 1.00 10.37 ? 195 HIS B C 1 ATOM 5532 O O . HIS B 1 195 ? 48.862 48.304 -3.555 1.00 9.75 ? 195 HIS B O 1 ATOM 5533 C CB . HIS B 1 195 ? 50.310 49.419 -0.893 1.00 9.98 ? 195 HIS B CB 1 ATOM 5534 C CG . HIS B 1 195 ? 50.603 50.549 0.047 1.00 10.80 ? 195 HIS B CG 1 ATOM 5535 N ND1 . HIS B 1 195 ? 51.879 51.012 0.274 1.00 11.86 ? 195 HIS B ND1 1 ATOM 5536 C CD2 . HIS B 1 195 ? 49.775 51.350 0.759 1.00 11.63 ? 195 HIS B CD2 1 ATOM 5537 C CE1 . HIS B 1 195 ? 51.827 52.053 1.090 1.00 13.57 ? 195 HIS B CE1 1 ATOM 5538 N NE2 . HIS B 1 195 ? 50.564 52.277 1.398 1.00 12.18 ? 195 HIS B NE2 1 ATOM 5539 N N . ALA B 1 196 ? 51.078 48.192 -3.892 1.00 10.04 ? 196 ALA B N 1 ATOM 5540 C CA . ALA B 1 196 ? 50.932 47.123 -4.868 1.00 9.90 ? 196 ALA B CA 1 ATOM 5541 C C . ALA B 1 196 ? 52.112 46.165 -4.949 1.00 10.02 ? 196 ALA B C 1 ATOM 5542 O O . ALA B 1 196 ? 53.055 46.246 -4.164 1.00 9.19 ? 196 ALA B O 1 ATOM 5543 C CB . ALA B 1 196 ? 50.662 47.730 -6.238 1.00 9.99 ? 196 ALA B CB 1 ATOM 5544 N N . ALA B 1 197 ? 52.049 45.264 -5.926 1.00 9.23 ? 197 ALA B N 1 ATOM 5545 C CA . ALA B 1 197 ? 53.083 44.256 -6.125 1.00 9.00 ? 197 ALA B CA 1 ATOM 5546 C C . ALA B 1 197 ? 54.483 44.820 -6.319 1.00 7.82 ? 197 ALA B C 1 ATOM 5547 O O . ALA B 1 197 ? 55.464 44.181 -5.940 1.00 8.25 ? 197 ALA B O 1 ATOM 5548 C CB . ALA B 1 197 ? 52.715 43.363 -7.311 1.00 7.63 ? 197 ALA B CB 1 ATOM 5549 N N . ASP B 1 198 ? 54.588 46.009 -6.902 1.00 9.55 ? 198 ASP B N 1 ATOM 5550 C CA . ASP B 1 198 ? 55.905 46.591 -7.123 1.00 9.72 ? 198 ASP B CA 1 ATOM 5551 C C . ASP B 1 198 ? 56.650 46.770 -5.800 1.00 9.44 ? 198 ASP B C 1 ATOM 5552 O O . ASP B 1 198 ? 57.869 46.641 -5.747 1.00 9.58 ? 198 ASP B O 1 ATOM 5553 C CB . ASP B 1 198 ? 55.785 47.929 -7.870 1.00 11.70 ? 198 ASP B CB 1 ATOM 5554 C CG . ASP B 1 198 ? 55.047 48.985 -7.074 1.00 11.83 ? 198 ASP B CG 1 ATOM 5555 O OD1 . ASP B 1 198 ? 53.945 48.696 -6.567 1.00 12.89 ? 198 ASP B OD1 1 ATOM 5556 O OD2 . ASP B 1 198 ? 55.568 50.117 -6.968 1.00 11.71 ? 198 ASP B OD2 1 ATOM 5557 N N . GLU B 1 199 ? 55.916 47.037 -4.726 1.00 10.40 ? 199 GLU B N 1 ATOM 5558 C CA . GLU B 1 199 ? 56.550 47.219 -3.426 1.00 9.25 ? 199 GLU B CA 1 ATOM 5559 C C . GLU B 1 199 ? 57.129 45.926 -2.864 1.00 10.60 ? 199 GLU B C 1 ATOM 5560 O O . GLU B 1 199 ? 57.996 45.955 -1.989 1.00 11.28 ? 199 GLU B O 1 ATOM 5561 C CB . GLU B 1 199 ? 55.558 47.820 -2.439 1.00 9.03 ? 199 GLU B CB 1 ATOM 5562 C CG . GLU B 1 199 ? 55.334 49.299 -2.645 1.00 9.14 ? 199 GLU B CG 1 ATOM 5563 C CD . GLU B 1 199 ? 54.196 49.811 -1.808 1.00 11.22 ? 199 GLU B CD 1 ATOM 5564 O OE1 . GLU B 1 199 ? 53.040 49.522 -2.169 1.00 11.34 ? 199 GLU B OE1 1 ATOM 5565 O OE2 . GLU B 1 199 ? 54.455 50.480 -0.784 1.00 11.53 ? 199 GLU B OE2 1 ATOM 5566 N N . LEU B 1 200 ? 56.660 44.786 -3.361 1.00 8.45 ? 200 LEU B N 1 ATOM 5567 C CA . LEU B 1 200 ? 57.187 43.517 -2.885 1.00 9.29 ? 200 LEU B CA 1 ATOM 5568 C C . LEU B 1 200 ? 58.624 43.333 -3.386 1.00 9.30 ? 200 LEU B C 1 ATOM 5569 O O . LEU B 1 200 ? 59.359 42.478 -2.893 1.00 11.00 ? 200 LEU B O 1 ATOM 5570 C CB . LEU B 1 200 ? 56.284 42.363 -3.336 1.00 8.34 ? 200 LEU B CB 1 ATOM 5571 C CG . LEU B 1 200 ? 54.869 42.466 -2.745 1.00 9.40 ? 200 LEU B CG 1 ATOM 5572 C CD1 . LEU B 1 200 ? 54.018 41.283 -3.193 1.00 10.33 ? 200 LEU B CD1 1 ATOM 5573 C CD2 . LEU B 1 200 ? 54.961 42.502 -1.223 1.00 10.63 ? 200 LEU B CD2 1 ATOM 5574 N N . LEU B 1 201 ? 59.021 44.153 -4.357 1.00 9.51 ? 201 LEU B N 1 ATOM 5575 C CA . LEU B 1 201 ? 60.382 44.105 -4.897 1.00 9.25 ? 201 LEU B CA 1 ATOM 5576 C C . LEU B 1 201 ? 61.359 44.551 -3.807 1.00 11.34 ? 201 LEU B C 1 ATOM 5577 O O . LEU B 1 201 ? 62.532 44.178 -3.819 1.00 11.85 ? 201 LEU B O 1 ATOM 5578 C CB . LEU B 1 201 ? 60.510 45.031 -6.110 1.00 9.36 ? 201 LEU B CB 1 ATOM 5579 C CG . LEU B 1 201 ? 59.707 44.666 -7.364 1.00 8.93 ? 201 LEU B CG 1 ATOM 5580 C CD1 . LEU B 1 201 ? 59.755 45.816 -8.361 1.00 8.85 ? 201 LEU B CD1 1 ATOM 5581 C CD2 . LEU B 1 201 ? 60.269 43.397 -7.986 1.00 9.28 ? 201 LEU B CD2 1 ATOM 5582 N N . ASN B 1 202 ? 60.863 45.353 -2.868 1.00 12.08 ? 202 ASN B N 1 ATOM 5583 C CA . ASN B 1 202 ? 61.680 45.852 -1.765 1.00 12.70 ? 202 ASN B CA 1 ATOM 5584 C C . ASN B 1 202 ? 62.073 44.737 -0.804 1.00 13.61 ? 202 ASN B C 1 ATOM 5585 O O . ASN B 1 202 ? 62.976 44.908 0.018 1.00 14.34 ? 202 ASN B O 1 ATOM 5586 C CB . ASN B 1 202 ? 60.929 46.937 -0.988 1.00 13.04 ? 202 ASN B CB 1 ATOM 5587 C CG . ASN B 1 202 ? 60.659 48.169 -1.821 1.00 13.86 ? 202 ASN B CG 1 ATOM 5588 O OD1 . ASN B 1 202 ? 61.567 48.720 -2.444 1.00 13.06 ? 202 ASN B OD1 1 ATOM 5589 N ND2 . ASN B 1 202 ? 59.408 48.616 -1.832 1.00 14.87 ? 202 ASN B ND2 1 ATOM 5590 N N . LYS B 1 203 ? 61.391 43.600 -0.907 1.00 13.68 ? 203 LYS B N 1 ATOM 5591 C CA . LYS B 1 203 ? 61.666 42.455 -0.047 1.00 15.15 ? 203 LYS B CA 1 ATOM 5592 C C . LYS B 1 203 ? 62.816 41.626 -0.614 1.00 14.12 ? 203 LYS B C 1 ATOM 5593 O O . LYS B 1 203 ? 63.340 40.736 0.055 1.00 15.51 ? 203 LYS B O 1 ATOM 5594 C CB . LYS B 1 203 ? 60.417 41.578 0.080 1.00 15.90 ? 203 LYS B CB 1 ATOM 5595 C CG . LYS B 1 203 ? 59.191 42.288 0.643 1.00 19.03 ? 203 LYS B CG 1 ATOM 5596 C CD . LYS B 1 203 ? 59.305 42.542 2.141 1.00 21.08 ? 203 LYS B CD 1 ATOM 5597 C CE . LYS B 1 203 ? 59.234 41.249 2.936 1.00 22.64 ? 203 LYS B CE 1 ATOM 5598 N NZ . LYS B 1 203 ? 59.262 41.503 4.406 1.00 23.38 ? 203 LYS B NZ 1 ATOM 5599 N N . GLY B 1 204 ? 63.197 41.920 -1.853 1.00 15.03 ? 204 GLY B N 1 ATOM 5600 C CA . GLY B 1 204 ? 64.285 41.196 -2.485 1.00 14.54 ? 204 GLY B CA 1 ATOM 5601 C C . GLY B 1 204 ? 65.629 41.772 -2.088 1.00 16.00 ? 204 GLY B C 1 ATOM 5602 O O . GLY B 1 204 ? 65.697 42.715 -1.300 1.00 15.78 ? 204 GLY B O 1 ATOM 5603 N N . ASN B 1 205 ? 66.701 41.205 -2.633 1.00 15.33 ? 205 ASN B N 1 ATOM 5604 C CA . ASN B 1 205 ? 68.048 41.676 -2.333 1.00 15.75 ? 205 ASN B CA 1 ATOM 5605 C C . ASN B 1 205 ? 68.430 42.714 -3.384 1.00 16.57 ? 205 ASN B C 1 ATOM 5606 O O . ASN B 1 205 ? 68.514 42.404 -4.573 1.00 16.33 ? 205 ASN B O 1 ATOM 5607 C CB . ASN B 1 205 ? 69.031 40.503 -2.365 1.00 16.11 ? 205 ASN B CB 1 ATOM 5608 C CG . ASN B 1 205 ? 70.421 40.897 -1.911 1.00 15.66 ? 205 ASN B CG 1 ATOM 5609 O OD1 . ASN B 1 205 ? 70.999 41.859 -2.414 1.00 17.70 ? 205 ASN B OD1 1 ATOM 5610 N ND2 . ASN B 1 205 ? 70.968 40.150 -0.957 1.00 18.20 ? 205 ASN B ND2 1 ATOM 5611 N N . SER B 1 206 ? 68.656 43.947 -2.942 1.00 15.67 ? 206 SER B N 1 ATOM 5612 C CA . SER B 1 206 ? 68.998 45.035 -3.848 1.00 18.07 ? 206 SER B CA 1 ATOM 5613 C C . SER B 1 206 ? 70.303 44.848 -4.617 1.00 17.83 ? 206 SER B C 1 ATOM 5614 O O . SER B 1 206 ? 70.580 45.592 -5.558 1.00 19.40 ? 206 SER B O 1 ATOM 5615 C CB . SER B 1 206 ? 69.036 46.361 -3.083 1.00 18.96 ? 206 SER B CB 1 ATOM 5616 O OG . SER B 1 206 ? 69.982 46.320 -2.029 1.00 21.35 ? 206 SER B OG 1 ATOM 5617 N N . ASN B 1 207 ? 71.105 43.862 -4.227 1.00 17.16 ? 207 ASN B N 1 ATOM 5618 C CA . ASN B 1 207 ? 72.367 43.617 -4.917 1.00 16.79 ? 207 ASN B CA 1 ATOM 5619 C C . ASN B 1 207 ? 72.254 42.452 -5.900 1.00 15.52 ? 207 ASN B C 1 ATOM 5620 O O . ASN B 1 207 ? 73.169 42.212 -6.692 1.00 14.13 ? 207 ASN B O 1 ATOM 5621 C CB . ASN B 1 207 ? 73.482 43.328 -3.907 1.00 18.89 ? 207 ASN B CB 1 ATOM 5622 C CG . ASN B 1 207 ? 74.861 43.326 -4.544 1.00 21.02 ? 207 ASN B CG 1 ATOM 5623 O OD1 . ASN B 1 207 ? 75.588 42.331 -4.480 1.00 22.62 ? 207 ASN B OD1 1 ATOM 5624 N ND2 . ASN B 1 207 ? 75.231 44.446 -5.158 1.00 20.27 ? 207 ASN B ND2 1 ATOM 5625 N N . ASN B 1 208 ? 71.132 41.735 -5.857 1.00 14.12 ? 208 ASN B N 1 ATOM 5626 C CA . ASN B 1 208 ? 70.918 40.596 -6.750 1.00 13.81 ? 208 ASN B CA 1 ATOM 5627 C C . ASN B 1 208 ? 69.758 40.800 -7.717 1.00 13.38 ? 208 ASN B C 1 ATOM 5628 O O . ASN B 1 208 ? 69.655 40.103 -8.725 1.00 14.02 ? 208 ASN B O 1 ATOM 5629 C CB . ASN B 1 208 ? 70.647 39.316 -5.952 1.00 13.35 ? 208 ASN B CB 1 ATOM 5630 C CG . ASN B 1 208 ? 71.793 38.936 -5.042 1.00 14.17 ? 208 ASN B CG 1 ATOM 5631 O OD1 . ASN B 1 208 ? 72.954 39.229 -5.329 1.00 16.63 ? 208 ASN B OD1 1 ATOM 5632 N ND2 . ASN B 1 208 ? 71.475 38.260 -3.942 1.00 12.70 ? 208 ASN B ND2 1 ATOM 5633 N N . LEU B 1 209 ? 68.889 41.756 -7.412 1.00 12.69 ? 209 LEU B N 1 ATOM 5634 C CA . LEU B 1 209 ? 67.721 42.014 -8.247 1.00 12.86 ? 209 LEU B CA 1 ATOM 5635 C C . LEU B 1 209 ? 67.852 43.251 -9.128 1.00 14.52 ? 209 LEU B C 1 ATOM 5636 O O . LEU B 1 209 ? 68.252 44.313 -8.660 1.00 14.79 ? 209 LEU B O 1 ATOM 5637 C CB . LEU B 1 209 ? 66.484 42.160 -7.352 1.00 13.03 ? 209 LEU B CB 1 ATOM 5638 C CG . LEU B 1 209 ? 65.106 42.420 -7.972 1.00 13.16 ? 209 LEU B CG 1 ATOM 5639 C CD1 . LEU B 1 209 ? 64.705 41.264 -8.883 1.00 14.65 ? 209 LEU B CD1 1 ATOM 5640 C CD2 . LEU B 1 209 ? 64.088 42.586 -6.851 1.00 13.99 ? 209 LEU B CD2 1 ATOM 5641 N N . ARG B 1 210 ? 67.517 43.092 -10.407 1.00 14.11 ? 210 ARG B N 1 ATOM 5642 C CA . ARG B 1 210 ? 67.537 44.186 -11.374 1.00 14.06 ? 210 ARG B CA 1 ATOM 5643 C C . ARG B 1 210 ? 66.194 44.175 -12.086 1.00 13.83 ? 210 ARG B C 1 ATOM 5644 O O . ARG B 1 210 ? 65.701 43.119 -12.487 1.00 13.18 ? 210 ARG B O 1 ATOM 5645 C CB . ARG B 1 210 ? 68.682 44.025 -12.388 1.00 15.59 ? 210 ARG B CB 1 ATOM 5646 C CG . ARG B 1 210 ? 70.057 44.381 -11.822 1.00 18.50 ? 210 ARG B CG 1 ATOM 5647 C CD . ARG B 1 210 ? 71.209 44.053 -12.778 1.00 20.88 ? 210 ARG B CD 1 ATOM 5648 N NE . ARG B 1 210 ? 71.400 45.037 -13.843 0.50 23.48 ? 210 ARG B NE 1 ATOM 5649 C CZ . ARG B 1 210 ? 71.916 46.252 -13.669 0.50 24.15 ? 210 ARG B CZ 1 ATOM 5650 N NH1 . ARG B 1 210 ? 72.302 46.655 -12.466 0.50 24.52 ? 210 ARG B NH1 1 ATOM 5651 N NH2 . ARG B 1 210 ? 72.052 47.065 -14.707 0.50 25.07 ? 210 ARG B NH2 1 ATOM 5652 N N . VAL B 1 211 ? 65.602 45.354 -12.219 1.00 12.19 ? 211 VAL B N 1 ATOM 5653 C CA . VAL B 1 211 ? 64.309 45.505 -12.872 1.00 12.95 ? 211 VAL B CA 1 ATOM 5654 C C . VAL B 1 211 ? 64.426 46.382 -14.110 1.00 13.96 ? 211 VAL B C 1 ATOM 5655 O O . VAL B 1 211 ? 64.966 47.486 -14.052 1.00 13.92 ? 211 VAL B O 1 ATOM 5656 C CB . VAL B 1 211 ? 63.275 46.153 -11.926 1.00 12.74 ? 211 VAL B CB 1 ATOM 5657 C CG1 . VAL B 1 211 ? 61.958 46.356 -12.657 1.00 14.11 ? 211 VAL B CG1 1 ATOM 5658 C CG2 . VAL B 1 211 ? 63.075 45.290 -10.689 1.00 12.40 ? 211 VAL B CG2 1 ATOM 5659 N N . GLY B 1 212 ? 63.913 45.886 -15.230 1.00 13.32 ? 212 GLY B N 1 ATOM 5660 C CA . GLY B 1 212 ? 63.955 46.658 -16.453 1.00 14.37 ? 212 GLY B CA 1 ATOM 5661 C C . GLY B 1 212 ? 62.552 47.055 -16.866 1.00 13.76 ? 212 GLY B C 1 ATOM 5662 O O . GLY B 1 212 ? 61.670 46.201 -16.955 1.00 14.69 ? 212 GLY B O 1 ATOM 5663 N N . VAL B 1 213 ? 62.330 48.348 -17.088 1.00 12.45 ? 213 VAL B N 1 ATOM 5664 C CA . VAL B 1 213 ? 61.016 48.820 -17.518 1.00 12.27 ? 213 VAL B CA 1 ATOM 5665 C C . VAL B 1 213 ? 61.103 49.230 -18.983 1.00 12.35 ? 213 VAL B C 1 ATOM 5666 O O . VAL B 1 213 ? 62.199 49.410 -19.515 1.00 13.36 ? 213 VAL B O 1 ATOM 5667 C CB . VAL B 1 213 ? 60.515 50.012 -16.667 1.00 12.55 ? 213 VAL B CB 1 ATOM 5668 C CG1 . VAL B 1 213 ? 60.350 49.574 -15.217 1.00 12.77 ? 213 VAL B CG1 1 ATOM 5669 C CG2 . VAL B 1 213 ? 61.484 51.184 -16.770 1.00 13.90 ? 213 VAL B CG2 1 ATOM 5670 N N . HIS B 1 214 ? 59.954 49.369 -19.636 1.00 13.03 ? 214 HIS B N 1 ATOM 5671 C CA . HIS B 1 214 ? 59.929 49.724 -21.051 1.00 12.74 ? 214 HIS B CA 1 ATOM 5672 C C . HIS B 1 214 ? 60.687 48.647 -21.818 1.00 13.15 ? 214 HIS B C 1 ATOM 5673 O O . HIS B 1 214 ? 61.379 48.926 -22.801 1.00 12.54 ? 214 HIS B O 1 ATOM 5674 C CB . HIS B 1 214 ? 60.575 51.094 -21.267 1.00 14.93 ? 214 HIS B CB 1 ATOM 5675 C CG . HIS B 1 214 ? 59.817 52.220 -20.637 1.00 16.86 ? 214 HIS B CG 1 ATOM 5676 N ND1 . HIS B 1 214 ? 60.432 53.363 -20.169 1.00 20.13 ? 214 HIS B ND1 1 ATOM 5677 C CD2 . HIS B 1 214 ? 58.494 52.388 -20.409 1.00 17.97 ? 214 HIS B CD2 1 ATOM 5678 C CE1 . HIS B 1 214 ? 59.521 54.182 -19.680 1.00 19.45 ? 214 HIS B CE1 1 ATOM 5679 N NE2 . HIS B 1 214 ? 58.335 53.615 -19.813 1.00 18.05 ? 214 HIS B NE2 1 ATOM 5680 N N . ALA B 1 215 ? 60.548 47.409 -21.347 1.00 12.40 ? 215 ALA B N 1 ATOM 5681 C CA . ALA B 1 215 ? 61.195 46.248 -21.950 1.00 12.56 ? 215 ALA B CA 1 ATOM 5682 C C . ALA B 1 215 ? 60.130 45.296 -22.485 1.00 11.78 ? 215 ALA B C 1 ATOM 5683 O O . ALA B 1 215 ? 59.441 44.624 -21.718 1.00 12.17 ? 215 ALA B O 1 ATOM 5684 C CB . ALA B 1 215 ? 62.057 45.535 -20.912 1.00 11.47 ? 215 ALA B CB 1 ATOM 5685 N N . SER B 1 216 ? 60.002 45.244 -23.806 1.00 11.93 ? 216 SER B N 1 ATOM 5686 C CA . SER B 1 216 ? 59.018 44.387 -24.455 1.00 11.47 ? 216 SER B CA 1 ATOM 5687 C C . SER B 1 216 ? 59.626 43.035 -24.813 1.00 11.32 ? 216 SER B C 1 ATOM 5688 O O . SER B 1 216 ? 60.416 42.936 -25.750 1.00 11.65 ? 216 SER B O 1 ATOM 5689 C CB . SER B 1 216 ? 58.501 45.075 -25.721 1.00 12.07 ? 216 SER B CB 1 ATOM 5690 O OG . SER B 1 216 ? 57.551 44.277 -26.403 1.00 11.75 ? 216 SER B OG 1 ATOM 5691 N N . VAL B 1 217 ? 59.265 41.998 -24.062 1.00 10.58 ? 217 VAL B N 1 ATOM 5692 C CA . VAL B 1 217 ? 59.788 40.661 -24.328 1.00 11.14 ? 217 VAL B CA 1 ATOM 5693 C C . VAL B 1 217 ? 59.028 40.081 -25.513 1.00 11.47 ? 217 VAL B C 1 ATOM 5694 O O . VAL B 1 217 ? 57.807 39.910 -25.463 1.00 10.92 ? 217 VAL B O 1 ATOM 5695 C CB . VAL B 1 217 ? 59.639 39.744 -23.101 1.00 9.49 ? 217 VAL B CB 1 ATOM 5696 C CG1 . VAL B 1 217 ? 60.236 38.369 -23.400 1.00 9.91 ? 217 VAL B CG1 1 ATOM 5697 C CG2 . VAL B 1 217 ? 60.340 40.378 -21.906 1.00 11.13 ? 217 VAL B CG2 1 ATOM 5698 N N . GLU B 1 218 ? 59.764 39.784 -26.580 1.00 11.37 ? 218 GLU B N 1 ATOM 5699 C CA . GLU B 1 218 ? 59.163 39.274 -27.810 1.00 12.72 ? 218 GLU B CA 1 ATOM 5700 C C . GLU B 1 218 ? 59.297 37.780 -28.075 1.00 13.59 ? 218 GLU B C 1 ATOM 5701 O O . GLU B 1 218 ? 58.482 37.212 -28.798 1.00 13.24 ? 218 GLU B O 1 ATOM 5702 C CB . GLU B 1 218 ? 59.750 40.006 -29.021 1.00 14.79 ? 218 GLU B CB 1 ATOM 5703 C CG . GLU B 1 218 ? 59.806 41.512 -28.894 1.00 17.21 ? 218 GLU B CG 1 ATOM 5704 C CD . GLU B 1 218 ? 60.374 42.165 -30.134 1.00 18.06 ? 218 GLU B CD 1 ATOM 5705 O OE1 . GLU B 1 218 ? 61.257 41.551 -30.772 1.00 18.69 ? 218 GLU B OE1 1 ATOM 5706 O OE2 . GLU B 1 218 ? 59.942 43.288 -30.469 1.00 18.72 ? 218 GLU B OE2 1 ATOM 5707 N N . LYS B 1 219 ? 60.311 37.140 -27.506 1.00 12.51 ? 219 LYS B N 1 ATOM 5708 C CA . LYS B 1 219 ? 60.516 35.728 -27.769 1.00 13.78 ? 219 LYS B CA 1 ATOM 5709 C C . LYS B 1 219 ? 61.355 35.027 -26.718 1.00 12.27 ? 219 LYS B C 1 ATOM 5710 O O . LYS B 1 219 ? 62.291 35.599 -26.161 1.00 13.63 ? 219 LYS B O 1 ATOM 5711 C CB . LYS B 1 219 ? 61.188 35.579 -29.147 1.00 16.49 ? 219 LYS B CB 1 ATOM 5712 C CG . LYS B 1 219 ? 61.309 34.154 -29.665 1.00 21.64 ? 219 LYS B CG 1 ATOM 5713 C CD . LYS B 1 219 ? 61.960 34.138 -31.053 1.00 23.98 ? 219 LYS B CD 1 ATOM 5714 C CE . LYS B 1 219 ? 61.957 32.734 -31.661 1.00 26.30 ? 219 LYS B CE 1 ATOM 5715 N NZ . LYS B 1 219 ? 62.526 32.708 -33.043 1.00 29.87 ? 219 LYS B NZ 1 ATOM 5716 N N . ILE B 1 220 ? 60.995 33.780 -26.447 1.00 11.90 ? 220 ILE B N 1 ATOM 5717 C CA . ILE B 1 220 ? 61.746 32.947 -25.522 1.00 13.08 ? 220 ILE B CA 1 ATOM 5718 C C . ILE B 1 220 ? 62.686 32.168 -26.439 1.00 13.76 ? 220 ILE B C 1 ATOM 5719 O O . ILE B 1 220 ? 62.255 31.648 -27.468 1.00 15.80 ? 220 ILE B O 1 ATOM 5720 C CB . ILE B 1 220 ? 60.843 31.953 -24.771 1.00 13.04 ? 220 ILE B CB 1 ATOM 5721 C CG1 . ILE B 1 220 ? 59.803 32.713 -23.943 1.00 13.54 ? 220 ILE B CG1 1 ATOM 5722 C CG2 . ILE B 1 220 ? 61.699 31.068 -23.871 1.00 13.73 ? 220 ILE B CG2 1 ATOM 5723 C CD1 . ILE B 1 220 ? 58.794 31.812 -23.271 1.00 17.35 ? 220 ILE B CD1 1 ATOM 5724 N N . ILE B 1 221 ? 63.963 32.096 -26.075 1.00 13.66 ? 221 ILE B N 1 ATOM 5725 C CA . ILE B 1 221 ? 64.951 31.385 -26.888 1.00 14.54 ? 221 ILE B CA 1 ATOM 5726 C C . ILE B 1 221 ? 65.128 29.958 -26.380 1.00 13.43 ? 221 ILE B C 1 ATOM 5727 O O . ILE B 1 221 ? 65.195 29.738 -25.171 1.00 12.66 ? 221 ILE B O 1 ATOM 5728 C CB . ILE B 1 221 ? 66.322 32.089 -26.837 1.00 15.96 ? 221 ILE B CB 1 ATOM 5729 C CG1 . ILE B 1 221 ? 66.160 33.569 -27.172 1.00 17.86 ? 221 ILE B CG1 1 ATOM 5730 C CG2 . ILE B 1 221 ? 67.284 31.433 -27.824 1.00 16.07 ? 221 ILE B CG2 1 ATOM 5731 C CD1 . ILE B 1 221 ? 67.412 34.392 -26.941 1.00 21.58 ? 221 ILE B CD1 1 ATOM 5732 N N . PHE B 1 222 ? 65.217 28.996 -27.297 1.00 14.04 ? 222 PHE B N 1 ATOM 5733 C CA . PHE B 1 222 ? 65.389 27.594 -26.913 1.00 14.54 ? 222 PHE B CA 1 ATOM 5734 C C . PHE B 1 222 ? 66.594 26.913 -27.539 1.00 16.19 ? 222 PHE B C 1 ATOM 5735 O O . PHE B 1 222 ? 67.113 27.359 -28.554 1.00 17.13 ? 222 PHE B O 1 ATOM 5736 C CB . PHE B 1 222 ? 64.154 26.775 -27.292 1.00 14.77 ? 222 PHE B CB 1 ATOM 5737 C CG . PHE B 1 222 ? 62.891 27.251 -26.651 1.00 15.62 ? 222 PHE B CG 1 ATOM 5738 C CD1 . PHE B 1 222 ? 62.030 28.102 -27.334 1.00 16.52 ? 222 PHE B CD1 1 ATOM 5739 C CD2 . PHE B 1 222 ? 62.562 26.853 -25.355 1.00 15.70 ? 222 PHE B CD2 1 ATOM 5740 C CE1 . PHE B 1 222 ? 60.843 28.553 -26.740 1.00 16.23 ? 222 PHE B CE1 1 ATOM 5741 C CE2 . PHE B 1 222 ? 61.381 27.293 -24.742 1.00 15.92 ? 222 PHE B CE2 1 ATOM 5742 C CZ . PHE B 1 222 ? 60.515 28.149 -25.437 1.00 14.28 ? 222 PHE B CZ 1 ATOM 5743 N N . SER B 1 223 ? 67.015 25.814 -26.922 1.00 17.42 ? 223 SER B N 1 ATOM 5744 C CA . SER B 1 223 ? 68.133 25.014 -27.408 1.00 19.35 ? 223 SER B CA 1 ATOM 5745 C C . SER B 1 223 ? 67.580 24.094 -28.484 1.00 20.75 ? 223 SER B C 1 ATOM 5746 O O . SER B 1 223 ? 66.369 24.001 -28.654 1.00 21.01 ? 223 SER B O 1 ATOM 5747 C CB . SER B 1 223 ? 68.724 24.174 -26.266 1.00 19.05 ? 223 SER B CB 1 ATOM 5748 O OG . SER B 1 223 ? 67.754 23.292 -25.748 1.00 18.29 ? 223 SER B OG 1 ATOM 5749 N N . ASN B 1 224 ? 68.467 23.411 -29.198 1.00 21.23 ? 224 ASN B N 1 ATOM 5750 C CA . ASN B 1 224 ? 68.056 22.485 -30.243 1.00 22.30 ? 224 ASN B CA 1 ATOM 5751 C C . ASN B 1 224 ? 67.377 21.270 -29.625 1.00 22.39 ? 224 ASN B C 1 ATOM 5752 O O . ASN B 1 224 ? 67.623 20.924 -28.469 1.00 22.91 ? 224 ASN B O 1 ATOM 5753 C CB . ASN B 1 224 ? 69.273 22.006 -31.046 1.00 23.44 ? 224 ASN B CB 1 ATOM 5754 C CG . ASN B 1 224 ? 70.010 23.138 -31.745 1.00 25.59 ? 224 ASN B CG 1 ATOM 5755 O OD1 . ASN B 1 224 ? 71.171 22.984 -32.131 1.00 27.32 ? 224 ASN B OD1 1 ATOM 5756 N ND2 . ASN B 1 224 ? 69.335 24.267 -31.936 1.00 25.83 ? 224 ASN B ND2 1 ATOM 5757 N N . ALA B 1 225 ? 66.512 20.622 -30.396 1.00 22.10 ? 225 ALA B N 1 ATOM 5758 C CA . ALA B 1 225 ? 65.843 19.420 -29.913 1.00 22.77 ? 225 ALA B CA 1 ATOM 5759 C C . ALA B 1 225 ? 66.844 18.283 -30.114 1.00 22.85 ? 225 ALA B C 1 ATOM 5760 O O . ALA B 1 225 ? 67.746 18.388 -30.948 1.00 22.28 ? 225 ALA B O 1 ATOM 5761 C CB . ALA B 1 225 ? 64.580 19.149 -30.708 1.00 24.46 ? 225 ALA B CB 1 ATOM 5762 N N . PRO B 1 226 ? 66.717 17.190 -29.335 1.00 23.50 ? 226 PRO B N 1 ATOM 5763 C CA . PRO B 1 226 ? 65.724 16.929 -28.286 1.00 24.06 ? 226 PRO B CA 1 ATOM 5764 C C . PRO B 1 226 ? 66.172 17.532 -26.951 1.00 24.38 ? 226 PRO B C 1 ATOM 5765 O O . PRO B 1 226 ? 67.207 18.191 -26.876 1.00 25.68 ? 226 PRO B O 1 ATOM 5766 C CB . PRO B 1 226 ? 65.677 15.403 -28.251 1.00 24.06 ? 226 PRO B CB 1 ATOM 5767 C CG . PRO B 1 226 ? 67.136 15.062 -28.404 1.00 23.53 ? 226 PRO B CG 1 ATOM 5768 C CD . PRO B 1 226 ? 67.560 15.996 -29.549 1.00 24.52 ? 226 PRO B CD 1 ATOM 5769 N N . GLY B 1 227 ? 65.407 17.293 -25.893 1.00 24.69 ? 227 GLY B N 1 ATOM 5770 C CA . GLY B 1 227 ? 65.778 17.838 -24.601 1.00 24.34 ? 227 GLY B CA 1 ATOM 5771 C C . GLY B 1 227 ? 65.725 19.354 -24.644 1.00 23.61 ? 227 GLY B C 1 ATOM 5772 O O . GLY B 1 227 ? 66.658 20.043 -24.230 1.00 25.44 ? 227 GLY B O 1 ATOM 5773 N N . LEU B 1 228 ? 64.625 19.876 -25.170 1.00 21.27 ? 228 LEU B N 1 ATOM 5774 C CA . LEU B 1 228 ? 64.415 21.315 -25.266 1.00 18.88 ? 228 LEU B CA 1 ATOM 5775 C C . LEU B 1 228 ? 64.603 22.033 -23.928 1.00 17.06 ? 228 LEU B C 1 ATOM 5776 O O . LEU B 1 228 ? 64.119 21.581 -22.885 1.00 16.64 ? 228 LEU B O 1 ATOM 5777 C CB . LEU B 1 228 ? 63.004 21.584 -25.787 1.00 20.00 ? 228 LEU B CB 1 ATOM 5778 C CG . LEU B 1 228 ? 62.716 20.988 -27.165 1.00 20.96 ? 228 LEU B CG 1 ATOM 5779 C CD1 . LEU B 1 228 ? 61.222 20.964 -27.426 1.00 21.91 ? 228 LEU B CD1 1 ATOM 5780 C CD2 . LEU B 1 228 ? 63.447 21.796 -28.222 1.00 21.91 ? 228 LEU B CD2 1 ATOM 5781 N N . THR B 1 229 ? 65.295 23.167 -23.972 1.00 16.06 ? 229 THR B N 1 ATOM 5782 C CA . THR B 1 229 ? 65.541 23.971 -22.781 1.00 15.70 ? 229 THR B CA 1 ATOM 5783 C C . THR B 1 229 ? 65.523 25.463 -23.105 1.00 14.81 ? 229 THR B C 1 ATOM 5784 O O . THR B 1 229 ? 66.103 25.894 -24.100 1.00 14.12 ? 229 THR B O 1 ATOM 5785 C CB . THR B 1 229 ? 66.906 23.628 -22.152 1.00 16.64 ? 229 THR B CB 1 ATOM 5786 O OG1 . THR B 1 229 ? 66.976 22.218 -21.915 1.00 19.09 ? 229 THR B OG1 1 ATOM 5787 C CG2 . THR B 1 229 ? 67.089 24.363 -20.829 1.00 17.08 ? 229 THR B CG2 1 ATOM 5788 N N . ALA B 1 230 ? 64.848 26.249 -22.269 1.00 12.16 ? 230 ALA B N 1 ATOM 5789 C CA . ALA B 1 230 ? 64.793 27.695 -22.465 1.00 13.04 ? 230 ALA B CA 1 ATOM 5790 C C . ALA B 1 230 ? 66.151 28.254 -22.046 1.00 13.60 ? 230 ALA B C 1 ATOM 5791 O O . ALA B 1 230 ? 66.638 27.964 -20.953 1.00 15.32 ? 230 ALA B O 1 ATOM 5792 C CB . ALA B 1 230 ? 63.686 28.298 -21.611 1.00 11.29 ? 230 ALA B CB 1 ATOM 5793 N N . THR B 1 231 ? 66.764 29.052 -22.914 1.00 13.83 ? 231 THR B N 1 ATOM 5794 C CA . THR B 1 231 ? 68.078 29.612 -22.621 1.00 13.79 ? 231 THR B CA 1 ATOM 5795 C C . THR B 1 231 ? 68.074 31.106 -22.317 1.00 13.75 ? 231 THR B C 1 ATOM 5796 O O . THR B 1 231 ? 69.068 31.646 -21.829 1.00 14.14 ? 231 THR B O 1 ATOM 5797 C CB . THR B 1 231 ? 69.049 29.349 -23.789 1.00 14.15 ? 231 THR B CB 1 ATOM 5798 O OG1 . THR B 1 231 ? 68.534 29.946 -24.985 1.00 16.51 ? 231 THR B OG1 1 ATOM 5799 C CG2 . THR B 1 231 ? 69.216 27.852 -24.009 1.00 14.83 ? 231 THR B CG2 1 ATOM 5800 N N . GLY B 1 232 ? 66.958 31.770 -22.596 1.00 11.90 ? 232 GLY B N 1 ATOM 5801 C CA . GLY B 1 232 ? 66.868 33.196 -22.344 1.00 11.98 ? 232 GLY B CA 1 ATOM 5802 C C . GLY B 1 232 ? 65.723 33.811 -23.121 1.00 11.50 ? 232 GLY B C 1 ATOM 5803 O O . GLY B 1 232 ? 64.851 33.097 -23.613 1.00 12.16 ? 232 GLY B O 1 ATOM 5804 N N . VAL B 1 233 ? 65.719 35.135 -23.233 1.00 12.31 ? 233 VAL B N 1 ATOM 5805 C CA . VAL B 1 233 ? 64.664 35.824 -23.963 1.00 13.11 ? 233 VAL B CA 1 ATOM 5806 C C . VAL B 1 233 ? 65.215 37.012 -24.741 1.00 13.03 ? 233 VAL B C 1 ATOM 5807 O O . VAL B 1 233 ? 66.324 37.483 -24.481 1.00 13.61 ? 233 VAL B O 1 ATOM 5808 C CB . VAL B 1 233 ? 63.563 36.358 -23.009 1.00 13.41 ? 233 VAL B CB 1 ATOM 5809 C CG1 . VAL B 1 233 ? 63.004 35.225 -22.161 1.00 12.48 ? 233 VAL B CG1 1 ATOM 5810 C CG2 . VAL B 1 233 ? 64.127 37.462 -22.126 1.00 13.79 ? 233 VAL B CG2 1 ATOM 5811 N N . ILE B 1 234 ? 64.429 37.483 -25.701 1.00 12.58 ? 234 ILE B N 1 ATOM 5812 C CA . ILE B 1 234 ? 64.791 38.642 -26.502 1.00 13.31 ? 234 ILE B CA 1 ATOM 5813 C C . ILE B 1 234 ? 63.796 39.742 -26.151 1.00 13.40 ? 234 ILE B C 1 ATOM 5814 O O . ILE B 1 234 ? 62.585 39.513 -26.176 1.00 14.18 ? 234 ILE B O 1 ATOM 5815 C CB . ILE B 1 234 ? 64.665 38.362 -28.012 1.00 14.22 ? 234 ILE B CB 1 ATOM 5816 C CG1 . ILE B 1 234 ? 65.582 37.207 -28.412 1.00 15.19 ? 234 ILE B CG1 1 ATOM 5817 C CG2 . ILE B 1 234 ? 64.991 39.627 -28.799 1.00 14.77 ? 234 ILE B CG2 1 ATOM 5818 C CD1 . ILE B 1 234 ? 65.437 36.784 -29.863 1.00 17.08 ? 234 ILE B CD1 1 ATOM 5819 N N . TYR B 1 235 ? 64.293 40.924 -25.804 1.00 13.13 ? 235 TYR B N 1 ATOM 5820 C CA . TYR B 1 235 ? 63.403 42.032 -25.482 1.00 13.50 ? 235 TYR B CA 1 ATOM 5821 C C . TYR B 1 235 ? 63.843 43.281 -26.234 1.00 15.10 ? 235 TYR B C 1 ATOM 5822 O O . TYR B 1 235 ? 65.014 43.425 -26.584 1.00 14.86 ? 235 TYR B O 1 ATOM 5823 C CB . TYR B 1 235 ? 63.350 42.269 -23.961 1.00 12.66 ? 235 TYR B CB 1 ATOM 5824 C CG . TYR B 1 235 ? 64.644 42.680 -23.297 1.00 13.59 ? 235 TYR B CG 1 ATOM 5825 C CD1 . TYR B 1 235 ? 64.955 44.026 -23.106 1.00 13.69 ? 235 TYR B CD1 1 ATOM 5826 C CD2 . TYR B 1 235 ? 65.543 41.724 -22.825 1.00 12.80 ? 235 TYR B CD2 1 ATOM 5827 C CE1 . TYR B 1 235 ? 66.122 44.411 -22.455 1.00 14.30 ? 235 TYR B CE1 1 ATOM 5828 C CE2 . TYR B 1 235 ? 66.717 42.099 -22.174 1.00 13.41 ? 235 TYR B CE2 1 ATOM 5829 C CZ . TYR B 1 235 ? 66.998 43.444 -21.992 1.00 15.16 ? 235 TYR B CZ 1 ATOM 5830 O OH . TYR B 1 235 ? 68.154 43.824 -21.350 1.00 18.24 ? 235 TYR B OH 1 ATOM 5831 N N . ARG B 1 236 ? 62.899 44.177 -26.501 1.00 15.26 ? 236 ARG B N 1 ATOM 5832 C CA . ARG B 1 236 ? 63.208 45.389 -27.251 1.00 16.85 ? 236 ARG B CA 1 ATOM 5833 C C . ARG B 1 236 ? 62.933 46.643 -26.425 1.00 18.02 ? 236 ARG B C 1 ATOM 5834 O O . ARG B 1 236 ? 61.949 46.700 -25.685 1.00 16.86 ? 236 ARG B O 1 ATOM 5835 C CB . ARG B 1 236 ? 62.372 45.411 -28.536 1.00 18.03 ? 236 ARG B CB 1 ATOM 5836 C CG . ARG B 1 236 ? 62.929 46.284 -29.653 1.00 19.73 ? 236 ARG B CG 1 ATOM 5837 C CD . ARG B 1 236 ? 62.045 46.192 -30.895 1.00 20.63 ? 236 ARG B CD 1 ATOM 5838 N NE . ARG B 1 236 ? 61.945 44.825 -31.404 1.00 21.30 ? 236 ARG B NE 1 ATOM 5839 C CZ . ARG B 1 236 ? 62.867 44.230 -32.155 1.00 22.70 ? 236 ARG B CZ 1 ATOM 5840 N NH1 . ARG B 1 236 ? 63.971 44.881 -32.501 1.00 23.51 ? 236 ARG B NH1 1 ATOM 5841 N NH2 . ARG B 1 236 ? 62.690 42.978 -32.559 1.00 23.36 ? 236 ARG B NH2 1 ATOM 5842 N N . ASP B 1 237 ? 63.804 47.645 -26.547 1.00 18.43 ? 237 ASP B N 1 ATOM 5843 C CA . ASP B 1 237 ? 63.627 48.890 -25.804 1.00 19.58 ? 237 ASP B CA 1 ATOM 5844 C C . ASP B 1 237 ? 62.899 49.951 -26.627 1.00 20.46 ? 237 ASP B C 1 ATOM 5845 O O . ASP B 1 237 ? 62.523 49.710 -27.777 1.00 20.03 ? 237 ASP B O 1 ATOM 5846 C CB . ASP B 1 237 ? 64.977 49.443 -25.313 1.00 19.86 ? 237 ASP B CB 1 ATOM 5847 C CG . ASP B 1 237 ? 65.921 49.814 -26.447 1.00 21.55 ? 237 ASP B CG 1 ATOM 5848 O OD1 . ASP B 1 237 ? 65.452 50.290 -27.500 1.00 21.88 ? 237 ASP B OD1 1 ATOM 5849 O OD2 . ASP B 1 237 ? 67.145 49.647 -26.270 1.00 21.56 ? 237 ASP B OD2 1 ATOM 5850 N N . SER B 1 238 ? 62.706 51.124 -26.031 1.00 20.44 ? 238 SER B N 1 ATOM 5851 C CA . SER B 1 238 ? 62.000 52.221 -26.687 1.00 21.96 ? 238 SER B CA 1 ATOM 5852 C C . SER B 1 238 ? 62.655 52.743 -27.963 1.00 22.85 ? 238 SER B C 1 ATOM 5853 O O . SER B 1 238 ? 62.007 53.428 -28.750 1.00 24.30 ? 238 SER B O 1 ATOM 5854 C CB . SER B 1 238 ? 61.789 53.377 -25.699 1.00 20.85 ? 238 SER B CB 1 ATOM 5855 O OG . SER B 1 238 ? 63.020 53.857 -25.193 1.00 23.08 ? 238 SER B OG 1 ATOM 5856 N N . ASN B 1 239 ? 63.931 52.431 -28.166 1.00 23.65 ? 239 ASN B N 1 ATOM 5857 C CA . ASN B 1 239 ? 64.626 52.878 -29.370 1.00 24.60 ? 239 ASN B CA 1 ATOM 5858 C C . ASN B 1 239 ? 64.488 51.858 -30.488 1.00 25.41 ? 239 ASN B C 1 ATOM 5859 O O . ASN B 1 239 ? 64.910 52.099 -31.615 1.00 25.71 ? 239 ASN B O 1 ATOM 5860 C CB . ASN B 1 239 ? 66.116 53.112 -29.092 1.00 25.53 ? 239 ASN B CB 1 ATOM 5861 C CG . ASN B 1 239 ? 66.363 54.315 -28.214 1.00 26.31 ? 239 ASN B CG 1 ATOM 5862 O OD1 . ASN B 1 239 ? 65.667 55.326 -28.320 1.00 27.88 ? 239 ASN B OD1 1 ATOM 5863 N ND2 . ASN B 1 239 ? 67.374 54.225 -27.358 1.00 25.76 ? 239 ASN B ND2 1 ATOM 5864 N N . GLY B 1 240 ? 63.897 50.714 -30.164 1.00 24.96 ? 240 GLY B N 1 ATOM 5865 C CA . GLY B 1 240 ? 63.730 49.665 -31.153 1.00 25.32 ? 240 GLY B CA 1 ATOM 5866 C C . GLY B 1 240 ? 64.905 48.712 -31.188 1.00 23.84 ? 240 GLY B C 1 ATOM 5867 O O . GLY B 1 240 ? 64.986 47.834 -32.045 1.00 25.48 ? 240 GLY B O 1 ATOM 5868 N N . THR B 1 241 ? 65.824 48.892 -30.249 1.00 23.66 ? 241 THR B N 1 ATOM 5869 C CA . THR B 1 241 ? 67.006 48.044 -30.161 1.00 23.85 ? 241 THR B CA 1 ATOM 5870 C C . THR B 1 241 ? 66.735 46.778 -29.352 1.00 22.82 ? 241 THR B C 1 ATOM 5871 O O . THR B 1 241 ? 66.207 46.840 -28.237 1.00 21.70 ? 241 THR B O 1 ATOM 5872 C CB . THR B 1 241 ? 68.172 48.794 -29.506 1.00 25.99 ? 241 THR B CB 1 ATOM 5873 O OG1 . THR B 1 241 ? 68.354 50.049 -30.170 1.00 28.08 ? 241 THR B OG1 1 ATOM 5874 C CG2 . THR B 1 241 ? 69.456 47.980 -29.607 1.00 27.18 ? 241 THR B CG2 1 ATOM 5875 N N . PRO B 1 242 ? 67.072 45.602 -29.917 1.00 21.86 ? 242 PRO B N 1 ATOM 5876 C CA . PRO B 1 242 ? 66.852 44.335 -29.214 1.00 21.55 ? 242 PRO B CA 1 ATOM 5877 C C . PRO B 1 242 ? 67.984 43.979 -28.262 1.00 21.84 ? 242 PRO B C 1 ATOM 5878 O O . PRO B 1 242 ? 69.153 44.230 -28.551 1.00 21.03 ? 242 PRO B O 1 ATOM 5879 C CB . PRO B 1 242 ? 66.728 43.331 -30.356 1.00 21.74 ? 242 PRO B CB 1 ATOM 5880 C CG . PRO B 1 242 ? 67.739 43.850 -31.337 1.00 21.33 ? 242 PRO B CG 1 ATOM 5881 C CD . PRO B 1 242 ? 67.472 45.354 -31.317 1.00 21.88 ? 242 PRO B CD 1 ATOM 5882 N N . HIS B 1 243 ? 67.623 43.392 -27.127 1.00 19.76 ? 243 HIS B N 1 ATOM 5883 C CA . HIS B 1 243 ? 68.588 42.965 -26.124 1.00 19.18 ? 243 HIS B CA 1 ATOM 5884 C C . HIS B 1 243 ? 68.328 41.491 -25.878 1.00 18.60 ? 243 HIS B C 1 ATOM 5885 O O . HIS B 1 243 ? 67.276 40.967 -26.246 1.00 17.28 ? 243 HIS B O 1 ATOM 5886 C CB . HIS B 1 243 ? 68.379 43.697 -24.799 1.00 19.37 ? 243 HIS B CB 1 ATOM 5887 C CG . HIS B 1 243 ? 68.486 45.184 -24.891 1.00 20.54 ? 243 HIS B CG 1 ATOM 5888 N ND1 . HIS B 1 243 ? 67.785 45.925 -25.818 1.00 21.96 ? 243 HIS B ND1 1 ATOM 5889 C CD2 . HIS B 1 243 ? 69.167 46.075 -24.134 1.00 21.80 ? 243 HIS B CD2 1 ATOM 5890 C CE1 . HIS B 1 243 ? 68.029 47.207 -25.625 1.00 22.38 ? 243 HIS B CE1 1 ATOM 5891 N NE2 . HIS B 1 243 ? 68.864 47.327 -24.609 1.00 22.53 ? 243 HIS B NE2 1 ATOM 5892 N N . GLN B 1 244 ? 69.283 40.830 -25.243 1.00 17.82 ? 244 GLN B N 1 ATOM 5893 C CA . GLN B 1 244 ? 69.135 39.425 -24.917 1.00 18.24 ? 244 GLN B CA 1 ATOM 5894 C C . GLN B 1 244 ? 69.571 39.199 -23.478 1.00 18.00 ? 244 GLN B C 1 ATOM 5895 O O . GLN B 1 244 ? 70.580 39.746 -23.030 1.00 17.28 ? 244 GLN B O 1 ATOM 5896 C CB . GLN B 1 244 ? 69.976 38.560 -25.858 1.00 20.18 ? 244 GLN B CB 1 ATOM 5897 C CG . GLN B 1 244 ? 69.446 38.488 -27.281 1.00 22.38 ? 244 GLN B CG 1 ATOM 5898 C CD . GLN B 1 244 ? 70.289 37.589 -28.167 1.00 24.01 ? 244 GLN B CD 1 ATOM 5899 O OE1 . GLN B 1 244 ? 71.451 37.886 -28.447 1.00 26.04 ? 244 GLN B OE1 1 ATOM 5900 N NE2 . GLN B 1 244 ? 69.709 36.478 -28.606 1.00 26.59 ? 244 GLN B NE2 1 ATOM 5901 N N . ALA B 1 245 ? 68.788 38.410 -22.752 1.00 16.57 ? 245 ALA B N 1 ATOM 5902 C CA . ALA B 1 245 ? 69.099 38.080 -21.368 1.00 14.61 ? 245 ALA B CA 1 ATOM 5903 C C . ALA B 1 245 ? 69.090 36.562 -21.297 1.00 16.01 ? 245 ALA B C 1 ATOM 5904 O O . ALA B 1 245 ? 68.079 35.929 -21.596 1.00 17.70 ? 245 ALA B O 1 ATOM 5905 C CB . ALA B 1 245 ? 68.048 38.662 -20.430 1.00 14.26 ? 245 ALA B CB 1 ATOM 5906 N N . PHE B 1 246 ? 70.219 35.977 -20.917 1.00 15.49 ? 246 PHE B N 1 ATOM 5907 C CA . PHE B 1 246 ? 70.318 34.528 -20.833 1.00 16.74 ? 246 PHE B CA 1 ATOM 5908 C C . PHE B 1 246 ? 70.369 34.046 -19.393 1.00 15.86 ? 246 PHE B C 1 ATOM 5909 O O . PHE B 1 246 ? 70.735 34.799 -18.490 1.00 16.30 ? 246 PHE B O 1 ATOM 5910 C CB . PHE B 1 246 ? 71.564 34.038 -21.579 1.00 17.69 ? 246 PHE B CB 1 ATOM 5911 C CG . PHE B 1 246 ? 71.601 34.435 -23.031 1.00 19.48 ? 246 PHE B CG 1 ATOM 5912 C CD1 . PHE B 1 246 ? 72.009 35.710 -23.410 1.00 20.78 ? 246 PHE B CD1 1 ATOM 5913 C CD2 . PHE B 1 246 ? 71.223 33.531 -24.018 1.00 21.39 ? 246 PHE B CD2 1 ATOM 5914 C CE1 . PHE B 1 246 ? 72.041 36.079 -24.755 1.00 22.35 ? 246 PHE B CE1 1 ATOM 5915 C CE2 . PHE B 1 246 ? 71.249 33.889 -25.365 1.00 21.55 ? 246 PHE B CE2 1 ATOM 5916 C CZ . PHE B 1 246 ? 71.660 35.165 -25.734 1.00 21.14 ? 246 PHE B CZ 1 ATOM 5917 N N . VAL B 1 247 ? 69.989 32.790 -19.183 1.00 16.06 ? 247 VAL B N 1 ATOM 5918 C CA . VAL B 1 247 ? 70.017 32.200 -17.850 1.00 17.18 ? 247 VAL B CA 1 ATOM 5919 C C . VAL B 1 247 ? 71.179 31.218 -17.774 1.00 16.22 ? 247 VAL B C 1 ATOM 5920 O O . VAL B 1 247 ? 71.504 30.550 -18.755 1.00 18.24 ? 247 VAL B O 1 ATOM 5921 C CB . VAL B 1 247 ? 68.695 31.463 -17.520 1.00 17.15 ? 247 VAL B CB 1 ATOM 5922 C CG1 . VAL B 1 247 ? 67.558 32.468 -17.401 1.00 18.77 ? 247 VAL B CG1 1 ATOM 5923 C CG2 . VAL B 1 247 ? 68.382 30.432 -18.592 1.00 17.24 ? 247 VAL B CG2 1 ATOM 5924 N N . ARG B 1 248 ? 71.811 31.138 -16.609 1.00 17.04 ? 248 ARG B N 1 ATOM 5925 C CA . ARG B 1 248 ? 72.946 30.245 -16.428 1.00 17.21 ? 248 ARG B CA 1 ATOM 5926 C C . ARG B 1 248 ? 72.524 28.853 -15.969 1.00 17.51 ? 248 ARG B C 1 ATOM 5927 O O . ARG B 1 248 ? 71.339 28.584 -15.773 1.00 17.53 ? 248 ARG B O 1 ATOM 5928 C CB . ARG B 1 248 ? 73.946 30.866 -15.441 1.00 18.05 ? 248 ARG B CB 1 ATOM 5929 C CG . ARG B 1 248 ? 74.551 32.177 -15.950 1.00 20.24 ? 248 ARG B CG 1 ATOM 5930 C CD . ARG B 1 248 ? 75.855 32.535 -15.242 1.00 21.66 ? 248 ARG B CD 1 ATOM 5931 N NE . ARG B 1 248 ? 75.657 33.088 -13.904 1.00 22.02 ? 248 ARG B NE 1 ATOM 5932 C CZ . ARG B 1 248 ? 75.430 34.373 -13.647 1.00 21.21 ? 248 ARG B CZ 1 ATOM 5933 N NH1 . ARG B 1 248 ? 75.369 35.254 -14.637 1.00 21.78 ? 248 ARG B NH1 1 ATOM 5934 N NH2 . ARG B 1 248 ? 75.274 34.779 -12.395 1.00 21.31 ? 248 ARG B NH2 1 ATOM 5935 N N . SER B 1 249 ? 73.501 27.964 -15.815 1.00 18.30 ? 249 SER B N 1 ATOM 5936 C CA . SER B 1 249 ? 73.243 26.590 -15.392 1.00 19.45 ? 249 SER B CA 1 ATOM 5937 C C . SER B 1 249 ? 72.259 26.508 -14.231 1.00 19.14 ? 249 SER B C 1 ATOM 5938 O O . SER B 1 249 ? 72.378 27.244 -13.251 1.00 20.61 ? 249 SER B O 1 ATOM 5939 C CB . SER B 1 249 ? 74.553 25.907 -14.993 1.00 20.17 ? 249 SER B CB 1 ATOM 5940 O OG . SER B 1 249 ? 74.333 24.546 -14.667 1.00 23.28 ? 249 SER B OG 1 ATOM 5941 N N . LYS B 1 250 ? 71.296 25.598 -14.354 1.00 17.98 ? 250 LYS B N 1 ATOM 5942 C CA . LYS B 1 250 ? 70.263 25.388 -13.341 1.00 18.52 ? 250 LYS B CA 1 ATOM 5943 C C . LYS B 1 250 ? 69.266 26.539 -13.236 1.00 17.24 ? 250 LYS B C 1 ATOM 5944 O O . LYS B 1 250 ? 68.287 26.457 -12.492 1.00 19.01 ? 250 LYS B O 1 ATOM 5945 C CB . LYS B 1 250 ? 70.903 25.144 -11.970 1.00 20.05 ? 250 LYS B CB 1 ATOM 5946 C CG . LYS B 1 250 ? 71.558 23.785 -11.809 1.00 23.39 ? 250 LYS B CG 1 ATOM 5947 C CD . LYS B 1 250 ? 72.010 23.587 -10.373 1.00 25.35 ? 250 LYS B CD 1 ATOM 5948 C CE . LYS B 1 250 ? 72.349 22.137 -10.088 1.00 28.43 ? 250 LYS B CE 1 ATOM 5949 N NZ . LYS B 1 250 ? 72.602 21.930 -8.637 1.00 28.61 ? 250 LYS B NZ 1 ATOM 5950 N N . GLY B 1 251 ? 69.521 27.612 -13.975 1.00 16.13 ? 251 GLY B N 1 ATOM 5951 C CA . GLY B 1 251 ? 68.633 28.761 -13.948 1.00 14.31 ? 251 GLY B CA 1 ATOM 5952 C C . GLY B 1 251 ? 67.403 28.538 -14.805 1.00 13.26 ? 251 GLY B C 1 ATOM 5953 O O . GLY B 1 251 ? 67.332 27.561 -15.551 1.00 13.00 ? 251 GLY B O 1 ATOM 5954 N N . GLU B 1 252 ? 66.438 29.448 -14.723 1.00 12.16 ? 252 GLU B N 1 ATOM 5955 C CA . GLU B 1 252 ? 65.213 29.290 -15.492 1.00 10.85 ? 252 GLU B CA 1 ATOM 5956 C C . GLU B 1 252 ? 64.598 30.604 -15.942 1.00 12.39 ? 252 GLU B C 1 ATOM 5957 O O . GLU B 1 252 ? 64.861 31.669 -15.375 1.00 10.28 ? 252 GLU B O 1 ATOM 5958 C CB . GLU B 1 252 ? 64.169 28.540 -14.657 1.00 13.52 ? 252 GLU B CB 1 ATOM 5959 C CG . GLU B 1 252 ? 64.653 27.234 -14.042 1.00 14.45 ? 252 GLU B CG 1 ATOM 5960 C CD . GLU B 1 252 ? 63.557 26.511 -13.279 1.00 16.83 ? 252 GLU B CD 1 ATOM 5961 O OE1 . GLU B 1 252 ? 62.494 26.246 -13.876 1.00 17.16 ? 252 GLU B OE1 1 ATOM 5962 O OE2 . GLU B 1 252 ? 63.758 26.200 -12.086 1.00 16.79 ? 252 GLU B OE2 1 ATOM 5963 N N . VAL B 1 253 ? 63.778 30.505 -16.980 1.00 11.73 ? 253 VAL B N 1 ATOM 5964 C CA . VAL B 1 253 ? 63.038 31.640 -17.504 1.00 11.00 ? 253 VAL B CA 1 ATOM 5965 C C . VAL B 1 253 ? 61.637 31.383 -16.961 1.00 11.29 ? 253 VAL B C 1 ATOM 5966 O O . VAL B 1 253 ? 61.123 30.270 -17.077 1.00 9.34 ? 253 VAL B O 1 ATOM 5967 C CB . VAL B 1 253 ? 62.978 31.630 -19.051 1.00 11.46 ? 253 VAL B CB 1 ATOM 5968 C CG1 . VAL B 1 253 ? 61.966 32.666 -19.542 1.00 9.24 ? 253 VAL B CG1 1 ATOM 5969 C CG2 . VAL B 1 253 ? 64.358 31.926 -19.634 1.00 10.22 ? 253 VAL B CG2 1 ATOM 5970 N N . ILE B 1 254 ? 61.036 32.386 -16.336 1.00 8.20 ? 254 ILE B N 1 ATOM 5971 C CA . ILE B 1 254 ? 59.689 32.227 -15.809 1.00 10.24 ? 254 ILE B CA 1 ATOM 5972 C C . ILE B 1 254 ? 58.820 33.308 -16.418 1.00 8.09 ? 254 ILE B C 1 ATOM 5973 O O . ILE B 1 254 ? 59.150 34.493 -16.354 1.00 9.75 ? 254 ILE B O 1 ATOM 5974 C CB . ILE B 1 254 ? 59.651 32.346 -14.274 1.00 10.71 ? 254 ILE B CB 1 ATOM 5975 C CG1 . ILE B 1 254 ? 60.554 31.275 -13.656 1.00 12.52 ? 254 ILE B CG1 1 ATOM 5976 C CG2 . ILE B 1 254 ? 58.211 32.164 -13.776 1.00 11.14 ? 254 ILE B CG2 1 ATOM 5977 C CD1 . ILE B 1 254 ? 60.814 31.461 -12.184 1.00 14.96 ? 254 ILE B CD1 1 ATOM 5978 N N . VAL B 1 255 ? 57.719 32.886 -17.027 1.00 8.55 ? 255 VAL B N 1 ATOM 5979 C CA . VAL B 1 255 ? 56.802 33.814 -17.663 1.00 8.50 ? 255 VAL B CA 1 ATOM 5980 C C . VAL B 1 255 ? 55.665 34.142 -16.699 1.00 7.77 ? 255 VAL B C 1 ATOM 5981 O O . VAL B 1 255 ? 54.955 33.251 -16.233 1.00 7.69 ? 255 VAL B O 1 ATOM 5982 C CB . VAL B 1 255 ? 56.236 33.205 -18.965 1.00 8.09 ? 255 VAL B CB 1 ATOM 5983 C CG1 . VAL B 1 255 ? 55.368 34.225 -19.687 1.00 10.68 ? 255 VAL B CG1 1 ATOM 5984 C CG2 . VAL B 1 255 ? 57.385 32.754 -19.867 1.00 10.54 ? 255 VAL B CG2 1 ATOM 5985 N N . SER B 1 256 ? 55.517 35.431 -16.400 1.00 6.46 ? 256 SER B N 1 ATOM 5986 C CA . SER B 1 256 ? 54.489 35.936 -15.490 1.00 7.63 ? 256 SER B CA 1 ATOM 5987 C C . SER B 1 256 ? 53.847 37.128 -16.188 1.00 7.65 ? 256 SER B C 1 ATOM 5988 O O . SER B 1 256 ? 53.527 38.140 -15.559 1.00 7.14 ? 256 SER B O 1 ATOM 5989 C CB . SER B 1 256 ? 55.134 36.395 -14.176 1.00 7.21 ? 256 SER B CB 1 ATOM 5990 O OG . SER B 1 256 ? 55.856 35.341 -13.552 1.00 9.33 ? 256 SER B OG 1 ATOM 5991 N N . ALA B 1 257 ? 53.655 36.991 -17.497 1.00 7.25 ? 257 ALA B N 1 ATOM 5992 C CA . ALA B 1 257 ? 53.097 38.059 -18.324 1.00 6.48 ? 257 ALA B CA 1 ATOM 5993 C C . ALA B 1 257 ? 51.578 38.187 -18.289 1.00 7.57 ? 257 ALA B C 1 ATOM 5994 O O . ALA B 1 257 ? 51.002 38.977 -19.030 1.00 7.75 ? 257 ALA B O 1 ATOM 5995 C CB . ALA B 1 257 ? 53.581 37.886 -19.766 1.00 7.58 ? 257 ALA B CB 1 ATOM 5996 N N . GLY B 1 258 ? 50.936 37.404 -17.428 1.00 6.30 ? 258 GLY B N 1 ATOM 5997 C CA . GLY B 1 258 ? 49.488 37.453 -17.286 1.00 7.48 ? 258 GLY B CA 1 ATOM 5998 C C . GLY B 1 258 ? 48.669 36.539 -18.179 1.00 8.31 ? 258 GLY B C 1 ATOM 5999 O O . GLY B 1 258 ? 49.180 35.915 -19.114 1.00 8.84 ? 258 GLY B O 1 ATOM 6000 N N . THR B 1 259 ? 47.378 36.467 -17.878 1.00 6.97 ? 259 THR B N 1 ATOM 6001 C CA . THR B 1 259 ? 46.433 35.643 -18.622 1.00 7.95 ? 259 THR B CA 1 ATOM 6002 C C . THR B 1 259 ? 46.500 35.914 -20.121 1.00 8.38 ? 259 THR B C 1 ATOM 6003 O O . THR B 1 259 ? 46.399 34.997 -20.937 1.00 9.02 ? 259 THR B O 1 ATOM 6004 C CB . THR B 1 259 ? 45.000 35.903 -18.112 1.00 8.52 ? 259 THR B CB 1 ATOM 6005 O OG1 . THR B 1 259 ? 44.909 35.488 -16.740 1.00 10.24 ? 259 THR B OG1 1 ATOM 6006 C CG2 . THR B 1 259 ? 43.972 35.153 -18.952 1.00 8.10 ? 259 THR B CG2 1 ATOM 6007 N N . ILE B 1 260 ? 46.684 37.176 -20.486 1.00 8.60 ? 260 ILE B N 1 ATOM 6008 C CA . ILE B 1 260 ? 46.760 37.549 -21.888 1.00 8.17 ? 260 ILE B CA 1 ATOM 6009 C C . ILE B 1 260 ? 48.186 37.476 -22.421 1.00 8.09 ? 260 ILE B C 1 ATOM 6010 O O . ILE B 1 260 ? 48.429 36.912 -23.486 1.00 8.70 ? 260 ILE B O 1 ATOM 6011 C CB . ILE B 1 260 ? 46.218 38.985 -22.112 1.00 9.30 ? 260 ILE B CB 1 ATOM 6012 C CG1 . ILE B 1 260 ? 44.789 39.101 -21.568 1.00 11.99 ? 260 ILE B CG1 1 ATOM 6013 C CG2 . ILE B 1 260 ? 46.247 39.324 -23.592 1.00 7.89 ? 260 ILE B CG2 1 ATOM 6014 C CD1 . ILE B 1 260 ? 43.804 38.126 -22.184 1.00 13.49 ? 260 ILE B CD1 1 ATOM 6015 N N . GLY B 1 261 ? 49.131 38.028 -21.668 1.00 8.37 ? 261 GLY B N 1 ATOM 6016 C CA . GLY B 1 261 ? 50.516 38.048 -22.110 1.00 8.21 ? 261 GLY B CA 1 ATOM 6017 C C . GLY B 1 261 ? 51.287 36.742 -22.181 1.00 8.06 ? 261 GLY B C 1 ATOM 6018 O O . GLY B 1 261 ? 52.091 36.552 -23.091 1.00 7.62 ? 261 GLY B O 1 ATOM 6019 N N . THR B 1 262 ? 51.062 35.845 -21.231 1.00 7.96 ? 262 THR B N 1 ATOM 6020 C CA . THR B 1 262 ? 51.786 34.577 -21.221 1.00 6.82 ? 262 THR B CA 1 ATOM 6021 C C . THR B 1 262 ? 51.477 33.670 -22.416 1.00 8.55 ? 262 THR B C 1 ATOM 6022 O O . THR B 1 262 ? 52.395 33.238 -23.117 1.00 7.65 ? 262 THR B O 1 ATOM 6023 C CB . THR B 1 262 ? 51.552 33.838 -19.891 1.00 6.50 ? 262 THR B CB 1 ATOM 6024 O OG1 . THR B 1 262 ? 52.221 34.556 -18.844 1.00 7.26 ? 262 THR B OG1 1 ATOM 6025 C CG2 . THR B 1 262 ? 52.094 32.418 -19.951 1.00 7.97 ? 262 THR B CG2 1 ATOM 6026 N N . PRO B 1 263 ? 50.192 33.376 -22.679 1.00 7.65 ? 263 PRO B N 1 ATOM 6027 C CA . PRO B 1 263 ? 49.902 32.510 -23.829 1.00 8.05 ? 263 PRO B CA 1 ATOM 6028 C C . PRO B 1 263 ? 50.409 33.149 -25.124 1.00 8.13 ? 263 PRO B C 1 ATOM 6029 O O . PRO B 1 263 ? 50.902 32.463 -26.015 1.00 8.90 ? 263 PRO B O 1 ATOM 6030 C CB . PRO B 1 263 ? 48.379 32.392 -23.806 1.00 8.74 ? 263 PRO B CB 1 ATOM 6031 C CG . PRO B 1 263 ? 48.035 32.590 -22.355 1.00 8.64 ? 263 PRO B CG 1 ATOM 6032 C CD . PRO B 1 263 ? 48.957 33.715 -21.949 1.00 7.88 ? 263 PRO B CD 1 ATOM 6033 N N . GLN B 1 264 ? 50.279 34.469 -25.222 1.00 7.98 ? 264 GLN B N 1 ATOM 6034 C CA . GLN B 1 264 ? 50.743 35.181 -26.407 1.00 8.76 ? 264 GLN B CA 1 ATOM 6035 C C . GLN B 1 264 ? 52.235 34.963 -26.639 1.00 7.26 ? 264 GLN B C 1 ATOM 6036 O O . GLN B 1 264 ? 52.648 34.632 -27.750 1.00 8.52 ? 264 GLN B O 1 ATOM 6037 C CB . GLN B 1 264 ? 50.476 36.684 -26.281 1.00 7.49 ? 264 GLN B CB 1 ATOM 6038 C CG . GLN B 1 264 ? 51.134 37.509 -27.382 1.00 8.62 ? 264 GLN B CG 1 ATOM 6039 C CD . GLN B 1 264 ? 50.972 39.002 -27.173 1.00 9.70 ? 264 GLN B CD 1 ATOM 6040 O OE1 . GLN B 1 264 ? 51.139 39.504 -26.063 1.00 9.44 ? 264 GLN B OE1 1 ATOM 6041 N NE2 . GLN B 1 264 ? 50.657 39.721 -28.245 1.00 9.29 ? 264 GLN B NE2 1 ATOM 6042 N N . LEU B 1 265 ? 53.043 35.159 -25.597 1.00 7.76 ? 265 LEU B N 1 ATOM 6043 C CA . LEU B 1 265 ? 54.490 34.989 -25.727 1.00 7.75 ? 265 LEU B CA 1 ATOM 6044 C C . LEU B 1 265 ? 54.867 33.546 -26.067 1.00 8.45 ? 265 LEU B C 1 ATOM 6045 O O . LEU B 1 265 ? 55.784 33.313 -26.860 1.00 10.01 ? 265 LEU B O 1 ATOM 6046 C CB . LEU B 1 265 ? 55.208 35.425 -24.443 1.00 9.34 ? 265 LEU B CB 1 ATOM 6047 C CG . LEU B 1 265 ? 56.734 35.263 -24.459 1.00 9.50 ? 265 LEU B CG 1 ATOM 6048 C CD1 . LEU B 1 265 ? 57.336 36.089 -25.598 1.00 11.32 ? 265 LEU B CD1 1 ATOM 6049 C CD2 . LEU B 1 265 ? 57.311 35.696 -23.117 1.00 10.50 ? 265 LEU B CD2 1 ATOM 6050 N N . LEU B 1 266 ? 54.170 32.580 -25.474 1.00 7.86 ? 266 LEU B N 1 ATOM 6051 C CA . LEU B 1 266 ? 54.459 31.175 -25.754 1.00 7.86 ? 266 LEU B CA 1 ATOM 6052 C C . LEU B 1 266 ? 54.188 30.859 -27.222 1.00 7.71 ? 266 LEU B C 1 ATOM 6053 O O . LEU B 1 266 ? 55.004 30.215 -27.881 1.00 7.97 ? 266 LEU B O 1 ATOM 6054 C CB . LEU B 1 266 ? 53.624 30.259 -24.853 1.00 7.59 ? 266 LEU B CB 1 ATOM 6055 C CG . LEU B 1 266 ? 54.050 30.234 -23.380 1.00 7.67 ? 266 LEU B CG 1 ATOM 6056 C CD1 . LEU B 1 266 ? 53.017 29.484 -22.553 1.00 9.18 ? 266 LEU B CD1 1 ATOM 6057 C CD2 . LEU B 1 266 ? 55.425 29.577 -23.253 1.00 8.90 ? 266 LEU B CD2 1 ATOM 6058 N N . LEU B 1 267 ? 53.049 31.316 -27.734 1.00 8.16 ? 267 LEU B N 1 ATOM 6059 C CA . LEU B 1 267 ? 52.709 31.078 -29.131 1.00 8.46 ? 267 LEU B CA 1 ATOM 6060 C C . LEU B 1 267 ? 53.755 31.707 -30.047 1.00 9.95 ? 267 LEU B C 1 ATOM 6061 O O . LEU B 1 267 ? 54.257 31.061 -30.967 1.00 10.03 ? 267 LEU B O 1 ATOM 6062 C CB . LEU B 1 267 ? 51.327 31.656 -29.450 1.00 9.29 ? 267 LEU B CB 1 ATOM 6063 C CG . LEU B 1 267 ? 50.142 30.970 -28.768 1.00 7.71 ? 267 LEU B CG 1 ATOM 6064 C CD1 . LEU B 1 267 ? 48.881 31.793 -28.986 1.00 9.33 ? 267 LEU B CD1 1 ATOM 6065 C CD2 . LEU B 1 267 ? 49.974 29.552 -29.313 1.00 8.71 ? 267 LEU B CD2 1 ATOM 6066 N N . LEU B 1 268 ? 54.087 32.968 -29.788 1.00 8.50 ? 268 LEU B N 1 ATOM 6067 C CA . LEU B 1 268 ? 55.075 33.674 -30.597 1.00 9.63 ? 268 LEU B CA 1 ATOM 6068 C C . LEU B 1 268 ? 56.444 33.001 -30.546 1.00 9.66 ? 268 LEU B C 1 ATOM 6069 O O . LEU B 1 268 ? 57.269 33.189 -31.443 1.00 11.63 ? 268 LEU B O 1 ATOM 6070 C CB . LEU B 1 268 ? 55.202 35.129 -30.129 1.00 8.60 ? 268 LEU B CB 1 ATOM 6071 C CG . LEU B 1 268 ? 54.045 36.077 -30.453 1.00 10.01 ? 268 LEU B CG 1 ATOM 6072 C CD1 . LEU B 1 268 ? 54.264 37.409 -29.747 1.00 10.30 ? 268 LEU B CD1 1 ATOM 6073 C CD2 . LEU B 1 268 ? 53.949 36.278 -31.960 1.00 10.39 ? 268 LEU B CD2 1 ATOM 6074 N N . SER B 1 269 ? 56.674 32.206 -29.505 1.00 8.86 ? 269 SER B N 1 ATOM 6075 C CA . SER B 1 269 ? 57.950 31.519 -29.330 1.00 9.05 ? 269 SER B CA 1 ATOM 6076 C C . SER B 1 269 ? 57.958 30.092 -29.867 1.00 10.37 ? 269 SER B C 1 ATOM 6077 O O . SER B 1 269 ? 58.931 29.363 -29.686 1.00 11.82 ? 269 SER B O 1 ATOM 6078 C CB . SER B 1 269 ? 58.337 31.514 -27.847 1.00 9.96 ? 269 SER B CB 1 ATOM 6079 O OG . SER B 1 269 ? 58.436 32.841 -27.357 1.00 9.80 ? 269 SER B OG 1 ATOM 6080 N N . GLY B 1 270 ? 56.871 29.686 -30.513 1.00 9.51 ? 270 GLY B N 1 ATOM 6081 C CA . GLY B 1 270 ? 56.819 28.345 -31.070 1.00 10.12 ? 270 GLY B CA 1 ATOM 6082 C C . GLY B 1 270 ? 56.285 27.261 -30.156 1.00 9.05 ? 270 GLY B C 1 ATOM 6083 O O . GLY B 1 270 ? 56.438 26.073 -30.448 1.00 10.77 ? 270 GLY B O 1 ATOM 6084 N N . VAL B 1 271 ? 55.666 27.649 -29.045 1.00 8.59 ? 271 VAL B N 1 ATOM 6085 C CA . VAL B 1 271 ? 55.099 26.665 -28.128 1.00 9.20 ? 271 VAL B CA 1 ATOM 6086 C C . VAL B 1 271 ? 53.578 26.787 -28.168 1.00 9.78 ? 271 VAL B C 1 ATOM 6087 O O . VAL B 1 271 ? 52.999 27.696 -27.571 1.00 9.05 ? 271 VAL B O 1 ATOM 6088 C CB . VAL B 1 271 ? 55.602 26.881 -26.683 1.00 9.95 ? 271 VAL B CB 1 ATOM 6089 C CG1 . VAL B 1 271 ? 55.043 25.802 -25.770 1.00 9.80 ? 271 VAL B CG1 1 ATOM 6090 C CG2 . VAL B 1 271 ? 57.122 26.861 -26.655 1.00 11.33 ? 271 VAL B CG2 1 ATOM 6091 N N . GLY B 1 272 ? 52.942 25.868 -28.889 1.00 8.29 ? 272 GLY B N 1 ATOM 6092 C CA . GLY B 1 272 ? 51.495 25.885 -29.019 1.00 8.06 ? 272 GLY B CA 1 ATOM 6093 C C . GLY B 1 272 ? 51.029 24.838 -30.014 1.00 9.35 ? 272 GLY B C 1 ATOM 6094 O O . GLY B 1 272 ? 51.841 24.036 -30.466 1.00 8.68 ? 272 GLY B O 1 ATOM 6095 N N . PRO B 1 273 ? 49.737 24.824 -30.387 1.00 9.35 ? 273 PRO B N 1 ATOM 6096 C CA . PRO B 1 273 ? 49.201 23.844 -31.342 1.00 10.19 ? 273 PRO B CA 1 ATOM 6097 C C . PRO B 1 273 ? 49.989 23.839 -32.647 1.00 10.55 ? 273 PRO B C 1 ATOM 6098 O O . PRO B 1 273 ? 50.138 24.872 -33.290 1.00 8.96 ? 273 PRO B O 1 ATOM 6099 C CB . PRO B 1 273 ? 47.762 24.309 -31.542 1.00 11.19 ? 273 PRO B CB 1 ATOM 6100 C CG . PRO B 1 273 ? 47.435 24.973 -30.231 1.00 10.94 ? 273 PRO B CG 1 ATOM 6101 C CD . PRO B 1 273 ? 48.685 25.758 -29.952 1.00 11.16 ? 273 PRO B CD 1 ATOM 6102 N N . GLU B 1 274 ? 50.485 22.668 -33.030 1.00 9.52 ? 274 GLU B N 1 ATOM 6103 C CA . GLU B 1 274 ? 51.283 22.518 -34.243 1.00 10.96 ? 274 GLU B CA 1 ATOM 6104 C C . GLU B 1 274 ? 50.626 23.093 -35.493 1.00 10.24 ? 274 GLU B C 1 ATOM 6105 O O . GLU B 1 274 ? 51.225 23.887 -36.209 1.00 11.19 ? 274 GLU B O 1 ATOM 6106 C CB . GLU B 1 274 ? 51.602 21.032 -34.462 1.00 13.50 ? 274 GLU B CB 1 ATOM 6107 C CG . GLU B 1 274 ? 52.677 20.736 -35.509 1.00 18.49 ? 274 GLU B CG 1 ATOM 6108 C CD . GLU B 1 274 ? 52.254 21.070 -36.925 1.00 21.09 ? 274 GLU B CD 1 ATOM 6109 O OE1 . GLU B 1 274 ? 51.096 20.771 -37.290 1.00 23.35 ? 274 GLU B OE1 1 ATOM 6110 O OE2 . GLU B 1 274 ? 53.088 21.611 -37.685 1.00 21.91 ? 274 GLU B OE2 1 ATOM 6111 N N . SER B 1 275 ? 49.391 22.697 -35.763 1.00 10.81 ? 275 SER B N 1 ATOM 6112 C CA . SER B 1 275 ? 48.729 23.188 -36.963 1.00 11.21 ? 275 SER B CA 1 ATOM 6113 C C . SER B 1 275 ? 48.437 24.686 -36.925 1.00 10.41 ? 275 SER B C 1 ATOM 6114 O O . SER B 1 275 ? 48.418 25.344 -37.964 1.00 10.91 ? 275 SER B O 1 ATOM 6115 C CB . SER B 1 275 ? 47.444 22.405 -37.222 1.00 13.53 ? 275 SER B CB 1 ATOM 6116 O OG . SER B 1 275 ? 46.508 22.599 -36.198 1.00 20.10 ? 275 SER B OG 1 ATOM 6117 N N . TYR B 1 276 ? 48.193 25.228 -35.736 1.00 10.18 ? 276 TYR B N 1 ATOM 6118 C CA . TYR B 1 276 ? 47.925 26.658 -35.609 1.00 9.13 ? 276 TYR B CA 1 ATOM 6119 C C . TYR B 1 276 ? 49.197 27.434 -35.917 1.00 9.46 ? 276 TYR B C 1 ATOM 6120 O O . TYR B 1 276 ? 49.202 28.338 -36.746 1.00 8.21 ? 276 TYR B O 1 ATOM 6121 C CB . TYR B 1 276 ? 47.439 27.009 -34.193 1.00 9.17 ? 276 TYR B CB 1 ATOM 6122 C CG . TYR B 1 276 ? 47.303 28.501 -33.958 1.00 9.92 ? 276 TYR B CG 1 ATOM 6123 C CD1 . TYR B 1 276 ? 46.254 29.226 -34.522 1.00 11.66 ? 276 TYR B CD1 1 ATOM 6124 C CD2 . TYR B 1 276 ? 48.251 29.195 -33.208 1.00 11.26 ? 276 TYR B CD2 1 ATOM 6125 C CE1 . TYR B 1 276 ? 46.153 30.604 -34.347 1.00 11.23 ? 276 TYR B CE1 1 ATOM 6126 C CE2 . TYR B 1 276 ? 48.161 30.573 -33.029 1.00 11.45 ? 276 TYR B CE2 1 ATOM 6127 C CZ . TYR B 1 276 ? 47.112 31.270 -33.602 1.00 12.94 ? 276 TYR B CZ 1 ATOM 6128 O OH . TYR B 1 276 ? 47.033 32.634 -33.440 1.00 13.29 ? 276 TYR B OH 1 ATOM 6129 N N . LEU B 1 277 ? 50.285 27.077 -35.246 1.00 7.57 ? 277 LEU B N 1 ATOM 6130 C CA . LEU B 1 277 ? 51.557 27.754 -35.461 1.00 8.12 ? 277 LEU B CA 1 ATOM 6131 C C . LEU B 1 277 ? 52.033 27.663 -36.904 1.00 8.93 ? 277 LEU B C 1 ATOM 6132 O O . LEU B 1 277 ? 52.448 28.654 -37.496 1.00 8.57 ? 277 LEU B O 1 ATOM 6133 C CB . LEU B 1 277 ? 52.624 27.195 -34.508 1.00 8.76 ? 277 LEU B CB 1 ATOM 6134 C CG . LEU B 1 277 ? 52.393 27.445 -33.009 1.00 8.87 ? 277 LEU B CG 1 ATOM 6135 C CD1 . LEU B 1 277 ? 53.515 26.808 -32.210 1.00 12.52 ? 277 LEU B CD1 1 ATOM 6136 C CD2 . LEU B 1 277 ? 52.339 28.939 -32.742 1.00 9.28 ? 277 LEU B CD2 1 ATOM 6137 N N . SER B 1 278 ? 51.977 26.474 -37.482 1.00 9.94 ? 278 SER B N 1 ATOM 6138 C CA . SER B 1 278 ? 52.414 26.329 -38.862 1.00 10.00 ? 278 SER B CA 1 ATOM 6139 C C . SER B 1 278 ? 51.533 27.110 -39.843 1.00 9.60 ? 278 SER B C 1 ATOM 6140 O O . SER B 1 278 ? 52.011 27.555 -40.881 1.00 11.45 ? 278 SER B O 1 ATOM 6141 C CB . SER B 1 278 ? 52.472 24.851 -39.264 1.00 13.32 ? 278 SER B CB 1 ATOM 6142 O OG A SER B 1 278 ? 51.192 24.266 -39.296 0.50 12.70 ? 278 SER B OG 1 ATOM 6143 O OG B SER B 1 278 ? 53.167 23.984 -38.466 0.50 13.64 ? 278 SER B OG 1 ATOM 6144 N N . SER B 1 279 ? 50.254 27.289 -39.524 1.00 10.38 ? 279 SER B N 1 ATOM 6145 C CA . SER B 1 279 ? 49.361 28.031 -40.417 1.00 10.33 ? 279 SER B CA 1 ATOM 6146 C C . SER B 1 279 ? 49.839 29.469 -40.518 1.00 11.27 ? 279 SER B C 1 ATOM 6147 O O . SER B 1 279 ? 49.579 30.153 -41.506 1.00 10.98 ? 279 SER B O 1 ATOM 6148 C CB . SER B 1 279 ? 47.911 28.010 -39.906 1.00 11.56 ? 279 SER B CB 1 ATOM 6149 O OG . SER B 1 279 ? 47.736 28.898 -38.819 1.00 12.89 ? 279 SER B OG 1 ATOM 6150 N N . LEU B 1 280 ? 50.549 29.923 -39.493 1.00 8.85 ? 280 LEU B N 1 ATOM 6151 C CA . LEU B 1 280 ? 51.061 31.290 -39.458 1.00 9.80 ? 280 LEU B CA 1 ATOM 6152 C C . LEU B 1 280 ? 52.555 31.360 -39.756 1.00 10.83 ? 280 LEU B C 1 ATOM 6153 O O . LEU B 1 280 ? 53.163 32.431 -39.686 1.00 10.71 ? 280 LEU B O 1 ATOM 6154 C CB . LEU B 1 280 ? 50.784 31.915 -38.088 1.00 10.08 ? 280 LEU B CB 1 ATOM 6155 C CG . LEU B 1 280 ? 49.313 32.019 -37.686 1.00 10.27 ? 280 LEU B CG 1 ATOM 6156 C CD1 . LEU B 1 280 ? 49.208 32.618 -36.292 1.00 12.48 ? 280 LEU B CD1 1 ATOM 6157 C CD2 . LEU B 1 280 ? 48.565 32.874 -38.702 1.00 11.29 ? 280 LEU B CD2 1 ATOM 6158 N N . ASN B 1 281 ? 53.138 30.209 -40.079 1.00 10.36 ? 281 ASN B N 1 ATOM 6159 C CA . ASN B 1 281 ? 54.559 30.104 -40.392 1.00 11.20 ? 281 ASN B CA 1 ATOM 6160 C C . ASN B 1 281 ? 55.466 30.368 -39.193 1.00 10.19 ? 281 ASN B C 1 ATOM 6161 O O . ASN B 1 281 ? 56.610 30.792 -39.354 1.00 12.78 ? 281 ASN B O 1 ATOM 6162 C CB . ASN B 1 281 ? 54.923 31.049 -41.539 1.00 11.97 ? 281 ASN B CB 1 ATOM 6163 C CG . ASN B 1 281 ? 54.287 30.637 -42.848 1.00 13.34 ? 281 ASN B CG 1 ATOM 6164 O OD1 . ASN B 1 281 ? 54.016 31.473 -43.709 1.00 16.28 ? 281 ASN B OD1 1 ATOM 6165 N ND2 . ASN B 1 281 ? 54.057 29.340 -43.012 1.00 11.86 ? 281 ASN B ND2 1 ATOM 6166 N N . ILE B 1 282 ? 54.945 30.134 -37.993 1.00 9.61 ? 282 ILE B N 1 ATOM 6167 C CA . ILE B 1 282 ? 55.737 30.306 -36.781 1.00 9.69 ? 282 ILE B CA 1 ATOM 6168 C C . ILE B 1 282 ? 56.395 28.949 -36.535 1.00 10.54 ? 282 ILE B C 1 ATOM 6169 O O . ILE B 1 282 ? 55.709 27.938 -36.408 1.00 10.29 ? 282 ILE B O 1 ATOM 6170 C CB . ILE B 1 282 ? 54.850 30.667 -35.570 1.00 9.25 ? 282 ILE B CB 1 ATOM 6171 C CG1 . ILE B 1 282 ? 54.204 32.039 -35.791 1.00 9.49 ? 282 ILE B CG1 1 ATOM 6172 C CG2 . ILE B 1 282 ? 55.691 30.665 -34.290 1.00 10.07 ? 282 ILE B CG2 1 ATOM 6173 C CD1 . ILE B 1 282 ? 53.118 32.382 -34.780 1.00 10.83 ? 282 ILE B CD1 1 ATOM 6174 N N . PRO B 1 283 ? 57.736 28.902 -36.498 1.00 12.03 ? 283 PRO B N 1 ATOM 6175 C CA . PRO B 1 283 ? 58.413 27.622 -36.267 1.00 12.80 ? 283 PRO B CA 1 ATOM 6176 C C . PRO B 1 283 ? 57.935 26.951 -34.986 1.00 12.66 ? 283 PRO B C 1 ATOM 6177 O O . PRO B 1 283 ? 57.827 27.595 -33.942 1.00 14.61 ? 283 PRO B O 1 ATOM 6178 C CB . PRO B 1 283 ? 59.883 28.020 -36.199 1.00 12.78 ? 283 PRO B CB 1 ATOM 6179 C CG . PRO B 1 283 ? 59.944 29.189 -37.139 1.00 14.94 ? 283 PRO B CG 1 ATOM 6180 C CD . PRO B 1 283 ? 58.713 29.974 -36.751 1.00 11.95 ? 283 PRO B CD 1 ATOM 6181 N N . VAL B 1 284 ? 57.646 25.658 -35.071 1.00 13.45 ? 284 VAL B N 1 ATOM 6182 C CA . VAL B 1 284 ? 57.173 24.907 -33.916 1.00 12.99 ? 284 VAL B CA 1 ATOM 6183 C C . VAL B 1 284 ? 58.324 24.336 -33.095 1.00 14.22 ? 284 VAL B C 1 ATOM 6184 O O . VAL B 1 284 ? 59.112 23.533 -33.595 1.00 15.28 ? 284 VAL B O 1 ATOM 6185 C CB . VAL B 1 284 ? 56.258 23.739 -34.348 1.00 13.12 ? 284 VAL B CB 1 ATOM 6186 C CG1 . VAL B 1 284 ? 55.839 22.921 -33.133 1.00 15.11 ? 284 VAL B CG1 1 ATOM 6187 C CG2 . VAL B 1 284 ? 55.031 24.282 -35.064 1.00 12.89 ? 284 VAL B CG2 1 ATOM 6188 N N . VAL B 1 285 ? 58.417 24.761 -31.839 1.00 12.26 ? 285 VAL B N 1 ATOM 6189 C CA . VAL B 1 285 ? 59.452 24.274 -30.933 1.00 12.24 ? 285 VAL B CA 1 ATOM 6190 C C . VAL B 1 285 ? 58.927 22.983 -30.309 1.00 11.93 ? 285 VAL B C 1 ATOM 6191 O O . VAL B 1 285 ? 59.630 21.977 -30.248 1.00 13.44 ? 285 VAL B O 1 ATOM 6192 C CB . VAL B 1 285 ? 59.760 25.311 -29.833 1.00 12.66 ? 285 VAL B CB 1 ATOM 6193 C CG1 . VAL B 1 285 ? 60.645 24.695 -28.758 1.00 11.80 ? 285 VAL B CG1 1 ATOM 6194 C CG2 . VAL B 1 285 ? 60.457 26.515 -30.451 1.00 13.50 ? 285 VAL B CG2 1 ATOM 6195 N N . LEU B 1 286 ? 57.680 23.020 -29.855 1.00 10.64 ? 286 LEU B N 1 ATOM 6196 C CA . LEU B 1 286 ? 57.037 21.850 -29.276 1.00 11.04 ? 286 LEU B CA 1 ATOM 6197 C C . LEU B 1 286 ? 55.530 22.013 -29.409 1.00 12.28 ? 286 LEU B C 1 ATOM 6198 O O . LEU B 1 286 ? 54.970 23.035 -29.003 1.00 12.32 ? 286 LEU B O 1 ATOM 6199 C CB . LEU B 1 286 ? 57.413 21.684 -27.799 1.00 12.59 ? 286 LEU B CB 1 ATOM 6200 C CG . LEU B 1 286 ? 56.760 20.505 -27.068 1.00 13.02 ? 286 LEU B CG 1 ATOM 6201 C CD1 . LEU B 1 286 ? 57.118 19.191 -27.754 1.00 15.28 ? 286 LEU B CD1 1 ATOM 6202 C CD2 . LEU B 1 286 ? 57.219 20.491 -25.616 1.00 15.03 ? 286 LEU B CD2 1 ATOM 6203 N N . SER B 1 287 ? 54.877 21.015 -29.994 1.00 11.69 ? 287 SER B N 1 ATOM 6204 C CA . SER B 1 287 ? 53.434 21.070 -30.158 1.00 11.11 ? 287 SER B CA 1 ATOM 6205 C C . SER B 1 287 ? 52.804 20.973 -28.772 1.00 11.95 ? 287 SER B C 1 ATOM 6206 O O . SER B 1 287 ? 52.961 19.970 -28.072 1.00 12.54 ? 287 SER B O 1 ATOM 6207 C CB . SER B 1 287 ? 52.942 19.925 -31.047 1.00 11.02 ? 287 SER B CB 1 ATOM 6208 O OG . SER B 1 287 ? 51.566 20.082 -31.343 1.00 12.67 ? 287 SER B OG 1 ATOM 6209 N N . HIS B 1 288 ? 52.105 22.034 -28.386 1.00 10.83 ? 288 HIS B N 1 ATOM 6210 C CA . HIS B 1 288 ? 51.451 22.137 -27.084 1.00 10.46 ? 288 HIS B CA 1 ATOM 6211 C C . HIS B 1 288 ? 50.006 22.557 -27.353 1.00 10.97 ? 288 HIS B C 1 ATOM 6212 O O . HIS B 1 288 ? 49.693 23.744 -27.429 1.00 10.72 ? 288 HIS B O 1 ATOM 6213 C CB . HIS B 1 288 ? 52.168 23.195 -26.243 1.00 12.08 ? 288 HIS B CB 1 ATOM 6214 C CG . HIS B 1 288 ? 52.752 22.663 -24.972 1.00 14.01 ? 288 HIS B CG 1 ATOM 6215 N ND1 . HIS B 1 288 ? 51.978 22.135 -23.963 1.00 14.90 ? 288 HIS B ND1 1 ATOM 6216 C CD2 . HIS B 1 288 ? 54.035 22.584 -24.545 1.00 14.61 ? 288 HIS B CD2 1 ATOM 6217 C CE1 . HIS B 1 288 ? 52.757 21.756 -22.965 1.00 14.31 ? 288 HIS B CE1 1 ATOM 6218 N NE2 . HIS B 1 288 ? 54.009 22.019 -23.292 1.00 14.09 ? 288 HIS B NE2 1 ATOM 6219 N N . PRO B 1 289 ? 49.106 21.576 -27.490 1.00 10.38 ? 289 PRO B N 1 ATOM 6220 C CA . PRO B 1 289 ? 47.681 21.779 -27.768 1.00 10.63 ? 289 PRO B CA 1 ATOM 6221 C C . PRO B 1 289 ? 46.900 22.794 -26.945 1.00 10.40 ? 289 PRO B C 1 ATOM 6222 O O . PRO B 1 289 ? 46.022 23.469 -27.480 1.00 10.82 ? 289 PRO B O 1 ATOM 6223 C CB . PRO B 1 289 ? 47.094 20.376 -27.610 1.00 12.34 ? 289 PRO B CB 1 ATOM 6224 C CG . PRO B 1 289 ? 48.231 19.489 -27.980 1.00 13.93 ? 289 PRO B CG 1 ATOM 6225 C CD . PRO B 1 289 ? 49.391 20.145 -27.282 1.00 11.36 ? 289 PRO B CD 1 ATOM 6226 N N . TYR B 1 290 ? 47.215 22.918 -25.661 1.00 9.07 ? 290 TYR B N 1 ATOM 6227 C CA . TYR B 1 290 ? 46.438 23.805 -24.808 1.00 8.00 ? 290 TYR B CA 1 ATOM 6228 C C . TYR B 1 290 ? 46.925 25.212 -24.501 1.00 8.89 ? 290 TYR B C 1 ATOM 6229 O O . TYR B 1 290 ? 46.329 25.901 -23.675 1.00 8.20 ? 290 TYR B O 1 ATOM 6230 C CB . TYR B 1 290 ? 46.107 23.063 -23.515 1.00 9.84 ? 290 TYR B CB 1 ATOM 6231 C CG . TYR B 1 290 ? 45.376 21.766 -23.792 1.00 11.68 ? 290 TYR B CG 1 ATOM 6232 C CD1 . TYR B 1 290 ? 45.945 20.536 -23.471 1.00 13.11 ? 290 TYR B CD1 1 ATOM 6233 C CD2 . TYR B 1 290 ? 44.132 21.772 -24.418 1.00 12.29 ? 290 TYR B CD2 1 ATOM 6234 C CE1 . TYR B 1 290 ? 45.289 19.339 -23.772 1.00 13.85 ? 290 TYR B CE1 1 ATOM 6235 C CE2 . TYR B 1 290 ? 43.469 20.586 -24.722 1.00 14.63 ? 290 TYR B CE2 1 ATOM 6236 C CZ . TYR B 1 290 ? 44.052 19.375 -24.397 1.00 15.20 ? 290 TYR B CZ 1 ATOM 6237 O OH . TYR B 1 290 ? 43.394 18.204 -24.697 1.00 18.26 ? 290 TYR B OH 1 ATOM 6238 N N . VAL B 1 291 ? 47.990 25.653 -25.158 1.00 7.82 ? 291 VAL B N 1 ATOM 6239 C CA . VAL B 1 291 ? 48.469 27.010 -24.936 1.00 7.59 ? 291 VAL B CA 1 ATOM 6240 C C . VAL B 1 291 ? 47.412 27.942 -25.534 1.00 8.20 ? 291 VAL B C 1 ATOM 6241 O O . VAL B 1 291 ? 47.070 27.828 -26.712 1.00 9.61 ? 291 VAL B O 1 ATOM 6242 C CB . VAL B 1 291 ? 49.831 27.248 -25.624 1.00 6.69 ? 291 VAL B CB 1 ATOM 6243 C CG1 . VAL B 1 291 ? 50.185 28.730 -25.594 1.00 6.96 ? 291 VAL B CG1 1 ATOM 6244 C CG2 . VAL B 1 291 ? 50.913 26.443 -24.907 1.00 8.71 ? 291 VAL B CG2 1 ATOM 6245 N N . GLY B 1 292 ? 46.877 28.840 -24.710 1.00 7.43 ? 292 GLY B N 1 ATOM 6246 C CA . GLY B 1 292 ? 45.856 29.763 -25.177 1.00 7.99 ? 292 GLY B CA 1 ATOM 6247 C C . GLY B 1 292 ? 44.447 29.204 -25.081 1.00 9.81 ? 292 GLY B C 1 ATOM 6248 O O . GLY B 1 292 ? 43.485 29.845 -25.505 1.00 9.08 ? 292 GLY B O 1 ATOM 6249 N N . GLN B 1 293 ? 44.316 28.001 -24.531 1.00 9.20 ? 293 GLN B N 1 ATOM 6250 C CA . GLN B 1 293 ? 43.005 27.383 -24.383 1.00 7.30 ? 293 GLN B CA 1 ATOM 6251 C C . GLN B 1 293 ? 42.528 27.524 -22.942 1.00 7.78 ? 293 GLN B C 1 ATOM 6252 O O . GLN B 1 293 ? 43.332 27.718 -22.029 1.00 8.41 ? 293 GLN B O 1 ATOM 6253 C CB . GLN B 1 293 ? 43.067 25.900 -24.772 1.00 8.89 ? 293 GLN B CB 1 ATOM 6254 C CG . GLN B 1 293 ? 43.505 25.652 -26.207 1.00 12.32 ? 293 GLN B CG 1 ATOM 6255 C CD . GLN B 1 293 ? 42.565 26.278 -27.221 1.00 13.49 ? 293 GLN B CD 1 ATOM 6256 O OE1 . GLN B 1 293 ? 41.371 25.977 -27.245 1.00 17.62 ? 293 GLN B OE1 1 ATOM 6257 N NE2 . GLN B 1 293 ? 43.100 27.152 -28.064 1.00 16.69 ? 293 GLN B NE2 1 ATOM 6258 N N . PHE B 1 294 ? 41.216 27.435 -22.755 1.00 8.92 ? 294 PHE B N 1 ATOM 6259 C CA . PHE B 1 294 ? 40.592 27.539 -21.444 1.00 9.81 ? 294 PHE B CA 1 ATOM 6260 C C . PHE B 1 294 ? 40.776 28.912 -20.807 1.00 10.02 ? 294 PHE B C 1 ATOM 6261 O O . PHE B 1 294 ? 41.305 29.034 -19.700 1.00 11.10 ? 294 PHE B O 1 ATOM 6262 C CB . PHE B 1 294 ? 41.130 26.447 -20.516 1.00 11.83 ? 294 PHE B CB 1 ATOM 6263 C CG . PHE B 1 294 ? 41.069 25.069 -21.110 1.00 14.12 ? 294 PHE B CG 1 ATOM 6264 C CD1 . PHE B 1 294 ? 42.236 24.380 -21.419 1.00 13.94 ? 294 PHE B CD1 1 ATOM 6265 C CD2 . PHE B 1 294 ? 39.844 24.465 -21.374 1.00 15.00 ? 294 PHE B CD2 1 ATOM 6266 C CE1 . PHE B 1 294 ? 42.188 23.109 -21.983 1.00 16.66 ? 294 PHE B CE1 1 ATOM 6267 C CE2 . PHE B 1 294 ? 39.783 23.191 -21.940 1.00 16.96 ? 294 PHE B CE2 1 ATOM 6268 C CZ . PHE B 1 294 ? 40.960 22.512 -22.245 1.00 17.61 ? 294 PHE B CZ 1 ATOM 6269 N N . LEU B 1 295 ? 40.350 29.943 -21.530 1.00 9.07 ? 295 LEU B N 1 ATOM 6270 C CA . LEU B 1 295 ? 40.400 31.326 -21.046 1.00 9.21 ? 295 LEU B CA 1 ATOM 6271 C C . LEU B 1 295 ? 39.055 31.565 -20.381 1.00 8.35 ? 295 LEU B C 1 ATOM 6272 O O . LEU B 1 295 ? 38.021 31.450 -21.033 1.00 9.73 ? 295 LEU B O 1 ATOM 6273 C CB . LEU B 1 295 ? 40.555 32.316 -22.204 1.00 11.60 ? 295 LEU B CB 1 ATOM 6274 C CG . LEU B 1 295 ? 41.935 32.756 -22.701 1.00 15.83 ? 295 LEU B CG 1 ATOM 6275 C CD1 . LEU B 1 295 ? 42.591 33.623 -21.657 1.00 15.09 ? 295 LEU B CD1 1 ATOM 6276 C CD2 . LEU B 1 295 ? 42.790 31.551 -23.033 1.00 15.94 ? 295 LEU B CD2 1 ATOM 6277 N N . HIS B 1 296 ? 39.062 31.910 -19.096 1.00 7.46 ? 296 HIS B N 1 ATOM 6278 C CA . HIS B 1 296 ? 37.823 32.143 -18.351 1.00 8.21 ? 296 HIS B CA 1 ATOM 6279 C C . HIS B 1 296 ? 37.675 33.580 -17.849 1.00 9.77 ? 296 HIS B C 1 ATOM 6280 O O . HIS B 1 296 ? 38.636 34.170 -17.362 1.00 12.19 ? 296 HIS B O 1 ATOM 6281 C CB . HIS B 1 296 ? 37.754 31.235 -17.113 1.00 8.70 ? 296 HIS B CB 1 ATOM 6282 C CG . HIS B 1 296 ? 37.810 29.768 -17.407 1.00 8.88 ? 296 HIS B CG 1 ATOM 6283 N ND1 . HIS B 1 296 ? 36.770 28.916 -17.106 1.00 9.05 ? 296 HIS B ND1 1 ATOM 6284 C CD2 . HIS B 1 296 ? 38.803 28.992 -17.900 1.00 7.49 ? 296 HIS B CD2 1 ATOM 6285 C CE1 . HIS B 1 296 ? 37.122 27.675 -17.395 1.00 8.50 ? 296 HIS B CE1 1 ATOM 6286 N NE2 . HIS B 1 296 ? 38.351 27.694 -17.879 1.00 8.59 ? 296 HIS B NE2 1 ATOM 6287 N N . ASP B 1 297 ? 36.474 34.144 -17.965 1.00 8.04 ? 297 ASP B N 1 ATOM 6288 C CA . ASP B 1 297 ? 36.234 35.486 -17.439 1.00 7.01 ? 297 ASP B CA 1 ATOM 6289 C C . ASP B 1 297 ? 34.901 35.516 -16.704 1.00 6.48 ? 297 ASP B C 1 ATOM 6290 O O . ASP B 1 297 ? 33.835 35.420 -17.321 1.00 7.14 ? 297 ASP B O 1 ATOM 6291 C CB . ASP B 1 297 ? 36.233 36.549 -18.538 1.00 6.78 ? 297 ASP B CB 1 ATOM 6292 C CG . ASP B 1 297 ? 36.208 37.958 -17.967 1.00 8.36 ? 297 ASP B CG 1 ATOM 6293 O OD1 . ASP B 1 297 ? 36.911 38.196 -16.959 1.00 7.12 ? 297 ASP B OD1 1 ATOM 6294 O OD2 . ASP B 1 297 ? 35.499 38.824 -18.524 1.00 8.41 ? 297 ASP B OD2 1 ATOM 6295 N N . ASN B 1 298 ? 34.960 35.646 -15.382 1.00 5.41 ? 298 ASN B N 1 ATOM 6296 C CA . ASN B 1 298 ? 33.745 35.682 -14.581 1.00 6.38 ? 298 ASN B CA 1 ATOM 6297 C C . ASN B 1 298 ? 32.892 36.863 -14.991 1.00 6.51 ? 298 ASN B C 1 ATOM 6298 O O . ASN B 1 298 ? 33.367 37.995 -15.038 1.00 8.22 ? 298 ASN B O 1 ATOM 6299 C CB . ASN B 1 298 ? 34.072 35.805 -13.094 1.00 5.50 ? 298 ASN B CB 1 ATOM 6300 C CG . ASN B 1 298 ? 35.034 34.736 -12.621 1.00 7.76 ? 298 ASN B CG 1 ATOM 6301 O OD1 . ASN B 1 298 ? 36.210 34.743 -12.983 1.00 8.59 ? 298 ASN B OD1 1 ATOM 6302 N ND2 . ASN B 1 298 ? 34.538 33.809 -11.809 1.00 8.56 ? 298 ASN B ND2 1 ATOM 6303 N N . PRO B 1 299 ? 31.620 36.614 -15.309 1.00 7.07 ? 299 PRO B N 1 ATOM 6304 C CA . PRO B 1 299 ? 30.756 37.726 -15.707 1.00 7.26 ? 299 PRO B CA 1 ATOM 6305 C C . PRO B 1 299 ? 30.332 38.611 -14.541 1.00 8.11 ? 299 PRO B C 1 ATOM 6306 O O . PRO B 1 299 ? 30.151 38.142 -13.413 1.00 9.71 ? 299 PRO B O 1 ATOM 6307 C CB . PRO B 1 299 ? 29.569 37.021 -16.361 1.00 8.30 ? 299 PRO B CB 1 ATOM 6308 C CG . PRO B 1 299 ? 29.490 35.722 -15.605 1.00 10.13 ? 299 PRO B CG 1 ATOM 6309 C CD . PRO B 1 299 ? 30.940 35.317 -15.485 1.00 6.98 ? 299 PRO B CD 1 ATOM 6310 N N . ARG B 1 300 ? 30.197 39.902 -14.820 1.00 8.08 ? 300 ARG B N 1 ATOM 6311 C CA . ARG B 1 300 ? 29.747 40.857 -13.819 1.00 7.94 ? 300 ARG B CA 1 ATOM 6312 C C . ARG B 1 300 ? 28.400 41.405 -14.265 1.00 8.35 ? 300 ARG B C 1 ATOM 6313 O O . ARG B 1 300 ? 28.242 41.826 -15.410 1.00 9.33 ? 300 ARG B O 1 ATOM 6314 C CB . ARG B 1 300 ? 30.735 42.024 -13.674 1.00 9.36 ? 300 ARG B CB 1 ATOM 6315 C CG . ARG B 1 300 ? 30.197 43.204 -12.842 1.00 8.22 ? 300 ARG B CG 1 ATOM 6316 C CD . ARG B 1 300 ? 31.313 44.181 -12.461 1.00 9.91 ? 300 ARG B CD 1 ATOM 6317 N NE . ARG B 1 300 ? 32.068 44.620 -13.629 1.00 11.35 ? 300 ARG B NE 1 ATOM 6318 C CZ . ARG B 1 300 ? 31.927 45.801 -14.226 1.00 9.78 ? 300 ARG B CZ 1 ATOM 6319 N NH1 . ARG B 1 300 ? 31.060 46.691 -13.765 1.00 10.45 ? 300 ARG B NH1 1 ATOM 6320 N NH2 . ARG B 1 300 ? 32.643 46.077 -15.307 1.00 10.75 ? 300 ARG B NH2 1 ATOM 6321 N N . ASN B 1 301 ? 27.417 41.357 -13.376 1.00 7.82 ? 301 ASN B N 1 ATOM 6322 C CA . ASN B 1 301 ? 26.113 41.924 -13.681 1.00 8.60 ? 301 ASN B CA 1 ATOM 6323 C C . ASN B 1 301 ? 25.867 42.887 -12.537 1.00 9.78 ? 301 ASN B C 1 ATOM 6324 O O . ASN B 1 301 ? 26.355 42.674 -11.422 1.00 9.55 ? 301 ASN B O 1 ATOM 6325 C CB . ASN B 1 301 ? 25.043 40.840 -13.821 1.00 9.64 ? 301 ASN B CB 1 ATOM 6326 C CG . ASN B 1 301 ? 25.221 40.031 -15.099 1.00 9.54 ? 301 ASN B CG 1 ATOM 6327 O OD1 . ASN B 1 301 ? 25.973 39.058 -15.131 1.00 10.69 ? 301 ASN B OD1 1 ATOM 6328 N ND2 . ASN B 1 301 ? 24.548 40.451 -16.168 1.00 10.46 ? 301 ASN B ND2 1 ATOM 6329 N N . PHE B 1 302 ? 25.116 43.947 -12.800 1.00 9.75 ? 302 PHE B N 1 ATOM 6330 C CA . PHE B 1 302 ? 24.972 44.982 -11.793 1.00 9.94 ? 302 PHE B CA 1 ATOM 6331 C C . PHE B 1 302 ? 23.733 45.850 -11.895 1.00 9.00 ? 302 PHE B C 1 ATOM 6332 O O . PHE B 1 302 ? 22.969 45.773 -12.855 1.00 9.92 ? 302 PHE B O 1 ATOM 6333 C CB . PHE B 1 302 ? 26.183 45.894 -11.938 1.00 9.08 ? 302 PHE B CB 1 ATOM 6334 C CG . PHE B 1 302 ? 26.343 46.435 -13.340 1.00 10.29 ? 302 PHE B CG 1 ATOM 6335 C CD1 . PHE B 1 302 ? 25.618 47.548 -13.759 1.00 10.40 ? 302 PHE B CD1 1 ATOM 6336 C CD2 . PHE B 1 302 ? 27.152 45.780 -14.266 1.00 11.20 ? 302 PHE B CD2 1 ATOM 6337 C CE1 . PHE B 1 302 ? 25.692 47.999 -15.079 1.00 9.66 ? 302 PHE B CE1 1 ATOM 6338 C CE2 . PHE B 1 302 ? 27.232 46.221 -15.586 1.00 10.84 ? 302 PHE B CE2 1 ATOM 6339 C CZ . PHE B 1 302 ? 26.499 47.333 -15.994 1.00 12.26 ? 302 PHE B CZ 1 ATOM 6340 N N . ILE B 1 303 ? 23.576 46.699 -10.882 1.00 9.26 ? 303 ILE B N 1 ATOM 6341 C CA . ILE B 1 303 ? 22.501 47.677 -10.819 1.00 7.39 ? 303 ILE B CA 1 ATOM 6342 C C . ILE B 1 303 ? 23.113 48.965 -10.269 1.00 8.33 ? 303 ILE B C 1 ATOM 6343 O O . ILE B 1 303 ? 23.781 48.957 -9.224 1.00 8.18 ? 303 ILE B O 1 ATOM 6344 C CB . ILE B 1 303 ? 21.342 47.237 -9.889 1.00 9.09 ? 303 ILE B CB 1 ATOM 6345 C CG1 . ILE B 1 303 ? 20.591 46.052 -10.503 1.00 7.20 ? 303 ILE B CG1 1 ATOM 6346 C CG2 . ILE B 1 303 ? 20.382 48.405 -9.673 1.00 8.80 ? 303 ILE B CG2 1 ATOM 6347 C CD1 . ILE B 1 303 ? 19.910 46.364 -11.834 1.00 9.65 ? 303 ILE B CD1 1 ATOM 6348 N N . ASN B 1 304 ? 22.904 50.061 -10.994 1.00 8.82 ? 304 ASN B N 1 ATOM 6349 C CA . ASN B 1 304 ? 23.404 51.374 -10.600 1.00 10.26 ? 304 ASN B CA 1 ATOM 6350 C C . ASN B 1 304 ? 22.245 52.195 -10.056 1.00 11.11 ? 304 ASN B C 1 ATOM 6351 O O . ASN B 1 304 ? 21.228 52.342 -10.732 1.00 11.58 ? 304 ASN B O 1 ATOM 6352 C CB . ASN B 1 304 ? 23.964 52.136 -11.803 1.00 10.85 ? 304 ASN B CB 1 ATOM 6353 C CG . ASN B 1 304 ? 25.042 51.380 -12.530 1.00 10.48 ? 304 ASN B CG 1 ATOM 6354 O OD1 . ASN B 1 304 ? 26.046 50.993 -11.941 1.00 9.76 ? 304 ASN B OD1 1 ATOM 6355 N ND2 . ASN B 1 304 ? 24.845 51.174 -13.827 1.00 10.69 ? 304 ASN B ND2 1 ATOM 6356 N N . ILE B 1 305 ? 22.393 52.733 -8.851 1.00 11.02 ? 305 ILE B N 1 ATOM 6357 C CA . ILE B 1 305 ? 21.342 53.571 -8.285 1.00 10.79 ? 305 ILE B CA 1 ATOM 6358 C C . ILE B 1 305 ? 21.887 54.976 -8.057 1.00 11.64 ? 305 ILE B C 1 ATOM 6359 O O . ILE B 1 305 ? 23.056 55.155 -7.697 1.00 10.69 ? 305 ILE B O 1 ATOM 6360 C CB . ILE B 1 305 ? 20.791 53.018 -6.941 1.00 10.42 ? 305 ILE B CB 1 ATOM 6361 C CG1 . ILE B 1 305 ? 21.864 53.080 -5.852 1.00 10.80 ? 305 ILE B CG1 1 ATOM 6362 C CG2 . ILE B 1 305 ? 20.285 51.593 -7.137 1.00 9.22 ? 305 ILE B CG2 1 ATOM 6363 C CD1 . ILE B 1 305 ? 21.328 52.835 -4.458 1.00 13.21 ? 305 ILE B CD1 1 ATOM 6364 N N . LEU B 1 306 ? 21.034 55.966 -8.299 1.00 12.03 ? 306 LEU B N 1 ATOM 6365 C CA . LEU B 1 306 ? 21.375 57.372 -8.114 1.00 13.31 ? 306 LEU B CA 1 ATOM 6366 C C . LEU B 1 306 ? 20.531 57.895 -6.953 1.00 14.36 ? 306 LEU B C 1 ATOM 6367 O O . LEU B 1 306 ? 19.368 58.250 -7.134 1.00 15.33 ? 306 LEU B O 1 ATOM 6368 C CB . LEU B 1 306 ? 21.054 58.159 -9.387 1.00 14.17 ? 306 LEU B CB 1 ATOM 6369 C CG . LEU B 1 306 ? 21.882 57.805 -10.627 1.00 14.34 ? 306 LEU B CG 1 ATOM 6370 C CD1 . LEU B 1 306 ? 21.098 58.125 -11.889 1.00 15.26 ? 306 LEU B CD1 1 ATOM 6371 C CD2 . LEU B 1 306 ? 23.197 58.562 -10.593 1.00 16.78 ? 306 LEU B CD2 1 ATOM 6372 N N . PRO B 1 307 ? 21.106 57.935 -5.742 1.00 13.56 ? 307 PRO B N 1 ATOM 6373 C CA . PRO B 1 307 ? 20.403 58.412 -4.544 1.00 15.28 ? 307 PRO B CA 1 ATOM 6374 C C . PRO B 1 307 ? 19.960 59.869 -4.660 1.00 16.23 ? 307 PRO B C 1 ATOM 6375 O O . PRO B 1 307 ? 20.596 60.668 -5.351 1.00 15.88 ? 307 PRO B O 1 ATOM 6376 C CB . PRO B 1 307 ? 21.438 58.227 -3.430 1.00 16.43 ? 307 PRO B CB 1 ATOM 6377 C CG . PRO B 1 307 ? 22.318 57.119 -3.945 1.00 17.80 ? 307 PRO B CG 1 ATOM 6378 C CD . PRO B 1 307 ? 22.465 57.480 -5.402 1.00 15.99 ? 307 PRO B CD 1 ATOM 6379 N N . PRO B 1 308 ? 18.857 60.232 -3.981 1.00 17.79 ? 308 PRO B N 1 ATOM 6380 C CA . PRO B 1 308 ? 18.339 61.604 -4.009 1.00 18.21 ? 308 PRO B CA 1 ATOM 6381 C C . PRO B 1 308 ? 19.270 62.556 -3.258 1.00 18.99 ? 308 PRO B C 1 ATOM 6382 O O . PRO B 1 308 ? 19.292 63.758 -3.520 1.00 18.55 ? 308 PRO B O 1 ATOM 6383 C CB . PRO B 1 308 ? 16.970 61.466 -3.348 1.00 19.17 ? 308 PRO B CB 1 ATOM 6384 C CG . PRO B 1 308 ? 17.176 60.357 -2.367 1.00 18.44 ? 308 PRO B CG 1 ATOM 6385 C CD . PRO B 1 308 ? 17.979 59.357 -3.184 1.00 18.00 ? 308 PRO B CD 1 ATOM 6386 N N . ASN B 1 309 ? 20.032 61.999 -2.321 1.00 18.90 ? 309 ASN B N 1 ATOM 6387 C CA . ASN B 1 309 ? 20.984 62.768 -1.535 1.00 19.11 ? 309 ASN B CA 1 ATOM 6388 C C . ASN B 1 309 ? 22.366 62.217 -1.826 1.00 19.56 ? 309 ASN B C 1 ATOM 6389 O O . ASN B 1 309 ? 22.534 61.015 -2.040 1.00 19.79 ? 309 ASN B O 1 ATOM 6390 C CB . ASN B 1 309 ? 20.655 62.660 -0.040 1.00 19.50 ? 309 ASN B CB 1 ATOM 6391 C CG . ASN B 1 309 ? 19.292 63.233 0.291 1.00 19.67 ? 309 ASN B CG 1 ATOM 6392 O OD1 . ASN B 1 309 ? 19.056 64.430 0.135 1.00 19.60 ? 309 ASN B OD1 1 ATOM 6393 N ND2 . ASN B 1 309 ? 18.384 62.377 0.744 1.00 20.69 ? 309 ASN B ND2 1 ATOM 6394 N N . PRO B 1 310 ? 23.382 63.092 -1.837 1.00 19.96 ? 310 PRO B N 1 ATOM 6395 C CA . PRO B 1 310 ? 24.756 62.661 -2.114 1.00 19.55 ? 310 PRO B CA 1 ATOM 6396 C C . PRO B 1 310 ? 25.288 61.568 -1.183 1.00 18.99 ? 310 PRO B C 1 ATOM 6397 O O . PRO B 1 310 ? 24.999 61.562 0.007 1.00 18.44 ? 310 PRO B O 1 ATOM 6398 C CB . PRO B 1 310 ? 25.568 63.956 -1.954 1.00 20.44 ? 310 PRO B CB 1 ATOM 6399 C CG . PRO B 1 310 ? 24.573 65.052 -2.178 1.00 20.25 ? 310 PRO B CG 1 ATOM 6400 C CD . PRO B 1 310 ? 23.344 64.525 -1.485 1.00 21.57 ? 310 PRO B CD 1 ATOM 6401 N N . ILE B 1 311 ? 26.051 60.636 -1.743 1.00 17.44 ? 311 ILE B N 1 ATOM 6402 C CA . ILE B 1 311 ? 26.699 59.600 -0.957 1.00 15.86 ? 311 ILE B CA 1 ATOM 6403 C C . ILE B 1 311 ? 28.172 59.809 -1.247 1.00 15.56 ? 311 ILE B C 1 ATOM 6404 O O . ILE B 1 311 ? 28.526 60.294 -2.318 1.00 16.68 ? 311 ILE B O 1 ATOM 6405 C CB . ILE B 1 311 ? 26.251 58.153 -1.341 1.00 14.78 ? 311 ILE B CB 1 ATOM 6406 C CG1 . ILE B 1 311 ? 26.452 57.883 -2.826 1.00 15.70 ? 311 ILE B CG1 1 ATOM 6407 C CG2 . ILE B 1 311 ? 24.811 57.932 -0.937 1.00 14.93 ? 311 ILE B CG2 1 ATOM 6408 C CD1 . ILE B 1 311 ? 26.161 56.435 -3.213 1.00 14.17 ? 311 ILE B CD1 1 ATOM 6409 N N . GLU B 1 312 ? 29.026 59.461 -0.298 1.00 15.60 ? 312 GLU B N 1 ATOM 6410 C CA . GLU B 1 312 ? 30.448 59.662 -0.489 1.00 15.66 ? 312 GLU B CA 1 ATOM 6411 C C . GLU B 1 312 ? 31.130 58.507 -1.215 1.00 15.64 ? 312 GLU B C 1 ATOM 6412 O O . GLU B 1 312 ? 30.734 57.345 -1.075 1.00 15.55 ? 312 GLU B O 1 ATOM 6413 C CB . GLU B 1 312 ? 31.125 59.893 0.865 1.00 17.41 ? 312 GLU B CB 1 ATOM 6414 C CG . GLU B 1 312 ? 31.431 58.638 1.674 1.00 20.64 ? 312 GLU B CG 1 ATOM 6415 C CD . GLU B 1 312 ? 30.212 57.787 2.009 1.00 22.04 ? 312 GLU B CD 1 ATOM 6416 O OE1 . GLU B 1 312 ? 29.063 58.268 1.898 1.00 23.94 ? 312 GLU B OE1 1 ATOM 6417 O OE2 . GLU B 1 312 ? 30.415 56.622 2.413 1.00 20.88 ? 312 GLU B OE2 1 ATOM 6418 N N . PRO B 1 313 ? 32.164 58.815 -2.018 1.00 15.75 ? 313 PRO B N 1 ATOM 6419 C CA . PRO B 1 313 ? 32.883 57.765 -2.747 1.00 15.61 ? 313 PRO B CA 1 ATOM 6420 C C . PRO B 1 313 ? 33.585 56.885 -1.715 1.00 14.16 ? 313 PRO B C 1 ATOM 6421 O O . PRO B 1 313 ? 34.014 57.366 -0.670 1.00 15.12 ? 313 PRO B O 1 ATOM 6422 C CB . PRO B 1 313 ? 33.890 58.550 -3.600 1.00 16.84 ? 313 PRO B CB 1 ATOM 6423 C CG . PRO B 1 313 ? 33.288 59.938 -3.696 1.00 18.08 ? 313 PRO B CG 1 ATOM 6424 C CD . PRO B 1 313 ? 32.734 60.140 -2.319 1.00 16.55 ? 313 PRO B CD 1 ATOM 6425 N N . THR B 1 314 ? 33.699 55.597 -1.999 1.00 13.76 ? 314 THR B N 1 ATOM 6426 C CA . THR B 1 314 ? 34.355 54.687 -1.071 1.00 13.09 ? 314 THR B CA 1 ATOM 6427 C C . THR B 1 314 ? 35.156 53.633 -1.810 1.00 12.66 ? 314 THR B C 1 ATOM 6428 O O . THR B 1 314 ? 34.990 53.445 -3.016 1.00 14.74 ? 314 THR B O 1 ATOM 6429 C CB . THR B 1 314 ? 33.326 53.941 -0.195 1.00 14.07 ? 314 THR B CB 1 ATOM 6430 O OG1 . THR B 1 314 ? 32.395 53.255 -1.042 1.00 12.60 ? 314 THR B OG1 1 ATOM 6431 C CG2 . THR B 1 314 ? 32.570 54.904 0.712 1.00 14.41 ? 314 THR B CG2 1 ATOM 6432 N N . ILE B 1 315 ? 36.052 52.968 -1.090 1.00 11.78 ? 315 ILE B N 1 ATOM 6433 C CA . ILE B 1 315 ? 36.802 51.876 -1.690 1.00 11.05 ? 315 ILE B CA 1 ATOM 6434 C C . ILE B 1 315 ? 36.013 50.649 -1.231 1.00 10.53 ? 315 ILE B C 1 ATOM 6435 O O . ILE B 1 315 ? 35.475 50.634 -0.123 1.00 9.92 ? 315 ILE B O 1 ATOM 6436 C CB . ILE B 1 315 ? 38.270 51.794 -1.179 1.00 12.09 ? 315 ILE B CB 1 ATOM 6437 C CG1 . ILE B 1 315 ? 38.313 51.650 0.342 1.00 14.10 ? 315 ILE B CG1 1 ATOM 6438 C CG2 . ILE B 1 315 ? 39.037 53.036 -1.614 1.00 13.75 ? 315 ILE B CG2 1 ATOM 6439 C CD1 . ILE B 1 315 ? 39.720 51.411 0.884 1.00 13.27 ? 315 ILE B CD1 1 ATOM 6440 N N . VAL B 1 316 ? 35.912 49.639 -2.085 1.00 8.95 ? 316 VAL B N 1 ATOM 6441 C CA . VAL B 1 316 ? 35.167 48.436 -1.733 1.00 8.92 ? 316 VAL B CA 1 ATOM 6442 C C . VAL B 1 316 ? 35.857 47.660 -0.619 1.00 7.43 ? 316 VAL B C 1 ATOM 6443 O O . VAL B 1 316 ? 37.047 47.350 -0.715 1.00 8.99 ? 316 VAL B O 1 ATOM 6444 C CB . VAL B 1 316 ? 34.998 47.512 -2.955 1.00 9.47 ? 316 VAL B CB 1 ATOM 6445 C CG1 . VAL B 1 316 ? 34.382 46.187 -2.527 1.00 9.53 ? 316 VAL B CG1 1 ATOM 6446 C CG2 . VAL B 1 316 ? 34.114 48.186 -3.992 1.00 12.60 ? 316 VAL B CG2 1 ATOM 6447 N N . THR B 1 317 ? 35.109 47.359 0.442 1.00 7.75 ? 317 THR B N 1 ATOM 6448 C CA . THR B 1 317 ? 35.652 46.603 1.566 1.00 8.00 ? 317 THR B CA 1 ATOM 6449 C C . THR B 1 317 ? 34.668 45.549 2.071 1.00 8.04 ? 317 THR B C 1 ATOM 6450 O O . THR B 1 317 ? 35.076 44.526 2.627 1.00 7.76 ? 317 THR B O 1 ATOM 6451 C CB . THR B 1 317 ? 36.011 47.518 2.757 1.00 8.97 ? 317 THR B CB 1 ATOM 6452 O OG1 . THR B 1 317 ? 34.824 48.155 3.245 1.00 9.28 ? 317 THR B OG1 1 ATOM 6453 C CG2 . THR B 1 317 ? 37.025 48.574 2.342 1.00 8.77 ? 317 THR B CG2 1 ATOM 6454 N N . VAL B 1 318 ? 33.377 45.803 1.878 1.00 6.13 ? 318 VAL B N 1 ATOM 6455 C CA . VAL B 1 318 ? 32.343 44.878 2.329 1.00 6.62 ? 318 VAL B CA 1 ATOM 6456 C C . VAL B 1 318 ? 31.967 43.891 1.232 1.00 6.93 ? 318 VAL B C 1 ATOM 6457 O O . VAL B 1 318 ? 31.562 44.281 0.135 1.00 7.56 ? 318 VAL B O 1 ATOM 6458 C CB . VAL B 1 318 ? 31.083 45.646 2.798 1.00 7.02 ? 318 VAL B CB 1 ATOM 6459 C CG1 . VAL B 1 318 ? 29.916 44.686 2.989 1.00 8.02 ? 318 VAL B CG1 1 ATOM 6460 C CG2 . VAL B 1 318 ? 31.383 46.360 4.108 1.00 7.87 ? 318 VAL B CG2 1 ATOM 6461 N N . LEU B 1 319 ? 32.116 42.605 1.538 1.00 6.62 ? 319 LEU B N 1 ATOM 6462 C CA . LEU B 1 319 ? 31.804 41.556 0.578 1.00 5.92 ? 319 LEU B CA 1 ATOM 6463 C C . LEU B 1 319 ? 30.669 40.657 1.056 1.00 6.41 ? 319 LEU B C 1 ATOM 6464 O O . LEU B 1 319 ? 30.609 40.273 2.227 1.00 7.74 ? 319 LEU B O 1 ATOM 6465 C CB . LEU B 1 319 ? 33.054 40.711 0.302 1.00 6.78 ? 319 LEU B CB 1 ATOM 6466 C CG . LEU B 1 319 ? 34.309 41.475 -0.139 1.00 7.65 ? 319 LEU B CG 1 ATOM 6467 C CD1 . LEU B 1 319 ? 35.421 40.486 -0.474 1.00 6.45 ? 319 LEU B CD1 1 ATOM 6468 C CD2 . LEU B 1 319 ? 33.988 42.335 -1.353 1.00 9.50 ? 319 LEU B CD2 1 ATOM 6469 N N . GLY B 1 320 ? 29.762 40.346 0.134 1.00 5.98 ? 320 GLY B N 1 ATOM 6470 C CA . GLY B 1 320 ? 28.632 39.478 0.422 1.00 7.55 ? 320 GLY B CA 1 ATOM 6471 C C . GLY B 1 320 ? 28.880 38.231 -0.403 1.00 8.41 ? 320 GLY B C 1 ATOM 6472 O O . GLY B 1 320 ? 28.624 38.204 -1.612 1.00 8.13 ? 320 GLY B O 1 ATOM 6473 N N . ILE B 1 321 ? 29.377 37.190 0.254 1.00 8.31 ? 321 ILE B N 1 ATOM 6474 C CA . ILE B 1 321 ? 29.737 35.958 -0.428 1.00 8.29 ? 321 ILE B CA 1 ATOM 6475 C C . ILE B 1 321 ? 28.740 34.807 -0.349 1.00 9.02 ? 321 ILE B C 1 ATOM 6476 O O . ILE B 1 321 ? 28.344 34.382 0.730 1.00 8.81 ? 321 ILE B O 1 ATOM 6477 C CB . ILE B 1 321 ? 31.100 35.437 0.105 1.00 8.05 ? 321 ILE B CB 1 ATOM 6478 C CG1 . ILE B 1 321 ? 32.172 36.521 -0.043 1.00 9.07 ? 321 ILE B CG1 1 ATOM 6479 C CG2 . ILE B 1 321 ? 31.506 34.165 -0.629 1.00 9.15 ? 321 ILE B CG2 1 ATOM 6480 C CD1 . ILE B 1 321 ? 32.442 36.959 -1.477 1.00 8.56 ? 321 ILE B CD1 1 ATOM 6481 N N . SER B 1 322 ? 28.335 34.318 -1.517 1.00 9.35 ? 322 SER B N 1 ATOM 6482 C CA . SER B 1 322 ? 27.445 33.167 -1.610 1.00 11.32 ? 322 SER B CA 1 ATOM 6483 C C . SER B 1 322 ? 28.274 32.098 -2.317 1.00 12.09 ? 322 SER B C 1 ATOM 6484 O O . SER B 1 322 ? 29.344 32.396 -2.849 1.00 12.46 ? 322 SER B O 1 ATOM 6485 C CB . SER B 1 322 ? 26.185 33.519 -2.412 1.00 12.17 ? 322 SER B CB 1 ATOM 6486 O OG . SER B 1 322 ? 25.391 34.477 -1.715 1.00 17.67 ? 322 SER B OG 1 ATOM 6487 N N . ASN B 1 323 ? 27.810 30.855 -2.316 1.00 13.18 ? 323 ASN B N 1 ATOM 6488 C CA . ASN B 1 323 ? 28.569 29.786 -2.954 1.00 14.35 ? 323 ASN B CA 1 ATOM 6489 C C . ASN B 1 323 ? 28.695 29.939 -4.461 1.00 13.41 ? 323 ASN B C 1 ATOM 6490 O O . ASN B 1 323 ? 29.734 29.621 -5.039 1.00 14.65 ? 323 ASN B O 1 ATOM 6491 C CB . ASN B 1 323 ? 27.940 28.421 -2.655 1.00 17.87 ? 323 ASN B CB 1 ATOM 6492 C CG . ASN B 1 323 ? 28.228 27.940 -1.250 1.00 22.14 ? 323 ASN B CG 1 ATOM 6493 O OD1 . ASN B 1 323 ? 27.311 27.694 -0.468 1.00 25.94 ? 323 ASN B OD1 1 ATOM 6494 N ND2 . ASN B 1 323 ? 29.507 27.795 -0.922 1.00 20.81 ? 323 ASN B ND2 1 ATOM 6495 N N . ASP B 1 324 ? 27.644 30.440 -5.098 1.00 11.63 ? 324 ASP B N 1 ATOM 6496 C CA . ASP B 1 324 ? 27.645 30.572 -6.548 1.00 11.16 ? 324 ASP B CA 1 ATOM 6497 C C . ASP B 1 324 ? 27.892 31.960 -7.125 1.00 8.65 ? 324 ASP B C 1 ATOM 6498 O O . ASP B 1 324 ? 28.033 32.104 -8.339 1.00 7.91 ? 324 ASP B O 1 ATOM 6499 C CB . ASP B 1 324 ? 26.331 30.015 -7.100 1.00 13.43 ? 324 ASP B CB 1 ATOM 6500 C CG . ASP B 1 324 ? 26.024 28.629 -6.568 1.00 14.81 ? 324 ASP B CG 1 ATOM 6501 O OD1 . ASP B 1 324 ? 26.933 27.775 -6.580 1.00 15.22 ? 324 ASP B OD1 1 ATOM 6502 O OD2 . ASP B 1 324 ? 24.874 28.396 -6.141 1.00 17.49 ? 324 ASP B OD2 1 ATOM 6503 N N . PHE B 1 325 ? 27.945 32.975 -6.270 1.00 7.58 ? 325 PHE B N 1 ATOM 6504 C CA . PHE B 1 325 ? 28.177 34.338 -6.729 1.00 6.58 ? 325 PHE B CA 1 ATOM 6505 C C . PHE B 1 325 ? 28.706 35.206 -5.590 1.00 6.74 ? 325 PHE B C 1 ATOM 6506 O O . PHE B 1 325 ? 28.411 34.959 -4.420 1.00 7.75 ? 325 PHE B O 1 ATOM 6507 C CB . PHE B 1 325 ? 26.885 34.917 -7.328 1.00 6.43 ? 325 PHE B CB 1 ATOM 6508 C CG . PHE B 1 325 ? 25.690 34.805 -6.424 1.00 6.84 ? 325 PHE B CG 1 ATOM 6509 C CD1 . PHE B 1 325 ? 25.476 35.736 -5.410 1.00 7.94 ? 325 PHE B CD1 1 ATOM 6510 C CD2 . PHE B 1 325 ? 24.786 33.753 -6.573 1.00 9.45 ? 325 PHE B CD2 1 ATOM 6511 C CE1 . PHE B 1 325 ? 24.380 35.622 -4.556 1.00 7.82 ? 325 PHE B CE1 1 ATOM 6512 C CE2 . PHE B 1 325 ? 23.685 33.630 -5.720 1.00 10.16 ? 325 PHE B CE2 1 ATOM 6513 C CZ . PHE B 1 325 ? 23.483 34.564 -4.713 1.00 7.50 ? 325 PHE B CZ 1 ATOM 6514 N N . TYR B 1 326 ? 29.497 36.214 -5.945 1.00 6.98 ? 326 TYR B N 1 ATOM 6515 C CA . TYR B 1 326 ? 30.112 37.111 -4.970 1.00 7.95 ? 326 TYR B CA 1 ATOM 6516 C C . TYR B 1 326 ? 29.657 38.539 -5.251 1.00 7.62 ? 326 TYR B C 1 ATOM 6517 O O . TYR B 1 326 ? 29.636 38.974 -6.405 1.00 8.43 ? 326 TYR B O 1 ATOM 6518 C CB . TYR B 1 326 ? 31.628 37.000 -5.086 1.00 8.41 ? 326 TYR B CB 1 ATOM 6519 C CG . TYR B 1 326 ? 32.106 35.586 -5.363 1.00 8.17 ? 326 TYR B CG 1 ATOM 6520 C CD1 . TYR B 1 326 ? 32.941 35.319 -6.445 1.00 7.72 ? 326 TYR B CD1 1 ATOM 6521 C CD2 . TYR B 1 326 ? 31.725 34.521 -4.547 1.00 8.53 ? 326 TYR B CD2 1 ATOM 6522 C CE1 . TYR B 1 326 ? 33.388 34.023 -6.711 1.00 11.48 ? 326 TYR B CE1 1 ATOM 6523 C CE2 . TYR B 1 326 ? 32.166 33.220 -4.805 1.00 10.60 ? 326 TYR B CE2 1 ATOM 6524 C CZ . TYR B 1 326 ? 32.998 32.984 -5.889 1.00 9.95 ? 326 TYR B CZ 1 ATOM 6525 O OH . TYR B 1 326 ? 33.446 31.711 -6.156 1.00 14.30 ? 326 TYR B OH 1 ATOM 6526 N N . GLN B 1 327 ? 29.320 39.281 -4.201 1.00 6.57 ? 327 GLN B N 1 ATOM 6527 C CA . GLN B 1 327 ? 28.803 40.630 -4.399 1.00 6.62 ? 327 GLN B CA 1 ATOM 6528 C C . GLN B 1 327 ? 29.413 41.730 -3.543 1.00 7.18 ? 327 GLN B C 1 ATOM 6529 O O . GLN B 1 327 ? 30.016 41.472 -2.503 1.00 7.90 ? 327 GLN B O 1 ATOM 6530 C CB . GLN B 1 327 ? 27.288 40.595 -4.193 1.00 7.19 ? 327 GLN B CB 1 ATOM 6531 C CG . GLN B 1 327 ? 26.641 39.388 -4.866 1.00 8.82 ? 327 GLN B CG 1 ATOM 6532 C CD . GLN B 1 327 ? 25.142 39.352 -4.714 1.00 8.56 ? 327 GLN B CD 1 ATOM 6533 O OE1 . GLN B 1 327 ? 24.617 39.433 -3.606 1.00 10.22 ? 327 GLN B OE1 1 ATOM 6534 N NE2 . GLN B 1 327 ? 24.438 39.217 -5.832 1.00 9.61 ? 327 GLN B NE2 1 ATOM 6535 N N . CYS B 1 328 ? 29.243 42.967 -3.999 1.00 8.32 ? 328 CYS B N 1 ATOM 6536 C CA . CYS B 1 328 ? 29.757 44.132 -3.293 1.00 9.50 ? 328 CYS B CA 1 ATOM 6537 C C . CYS B 1 328 ? 29.114 45.388 -3.863 1.00 9.25 ? 328 CYS B C 1 ATOM 6538 O O . CYS B 1 328 ? 28.317 45.321 -4.806 1.00 9.58 ? 328 CYS B O 1 ATOM 6539 C CB . CYS B 1 328 ? 31.279 44.227 -3.448 1.00 11.27 ? 328 CYS B CB 1 ATOM 6540 S SG . CYS B 1 328 ? 31.841 44.504 -5.148 1.00 16.22 ? 328 CYS B SG 1 ATOM 6541 N N . SER B 1 329 ? 29.462 46.533 -3.292 1.00 8.51 ? 329 SER B N 1 ATOM 6542 C CA . SER B 1 329 ? 28.919 47.795 -3.766 1.00 9.32 ? 329 SER B CA 1 ATOM 6543 C C . SER B 1 329 ? 29.993 48.868 -3.763 1.00 10.61 ? 329 SER B C 1 ATOM 6544 O O . SER B 1 329 ? 30.692 49.068 -2.770 1.00 13.08 ? 329 SER B O 1 ATOM 6545 C CB . SER B 1 329 ? 27.735 48.234 -2.903 1.00 11.79 ? 329 SER B CB 1 ATOM 6546 O OG . SER B 1 329 ? 27.109 49.374 -3.465 1.00 12.24 ? 329 SER B OG 1 ATOM 6547 N N . PHE B 1 330 ? 30.117 49.547 -4.895 1.00 10.95 ? 330 PHE B N 1 ATOM 6548 C CA . PHE B 1 330 ? 31.095 50.608 -5.085 1.00 12.36 ? 330 PHE B CA 1 ATOM 6549 C C . PHE B 1 330 ? 30.354 51.942 -5.222 1.00 11.30 ? 330 PHE B C 1 ATOM 6550 O O . PHE B 1 330 ? 29.450 52.060 -6.043 1.00 12.44 ? 330 PHE B O 1 ATOM 6551 C CB . PHE B 1 330 ? 31.891 50.305 -6.364 1.00 10.93 ? 330 PHE B CB 1 ATOM 6552 C CG . PHE B 1 330 ? 32.779 51.424 -6.828 1.00 14.64 ? 330 PHE B CG 1 ATOM 6553 C CD1 . PHE B 1 330 ? 33.826 51.882 -6.037 1.00 16.88 ? 330 PHE B CD1 1 ATOM 6554 C CD2 . PHE B 1 330 ? 32.593 51.990 -8.089 1.00 14.77 ? 330 PHE B CD2 1 ATOM 6555 C CE1 . PHE B 1 330 ? 34.682 52.888 -6.497 1.00 18.66 ? 330 PHE B CE1 1 ATOM 6556 C CE2 . PHE B 1 330 ? 33.440 52.993 -8.559 1.00 15.84 ? 330 PHE B CE2 1 ATOM 6557 C CZ . PHE B 1 330 ? 34.487 53.443 -7.762 1.00 16.90 ? 330 PHE B CZ 1 ATOM 6558 N N . SER B 1 331 ? 30.713 52.932 -4.409 1.00 10.41 ? 331 SER B N 1 ATOM 6559 C CA . SER B 1 331 ? 30.080 54.250 -4.507 1.00 11.94 ? 331 SER B CA 1 ATOM 6560 C C . SER B 1 331 ? 31.115 55.184 -5.126 1.00 11.32 ? 331 SER B C 1 ATOM 6561 O O . SER B 1 331 ? 32.300 55.118 -4.796 1.00 12.03 ? 331 SER B O 1 ATOM 6562 C CB . SER B 1 331 ? 29.626 54.758 -3.132 1.00 11.05 ? 331 SER B CB 1 ATOM 6563 O OG . SER B 1 331 ? 30.710 54.895 -2.234 1.00 10.62 ? 331 SER B OG 1 ATOM 6564 N N . SER B 1 332 ? 30.672 56.055 -6.021 1.00 11.70 ? 332 SER B N 1 ATOM 6565 C CA . SER B 1 332 ? 31.593 56.944 -6.709 1.00 13.88 ? 332 SER B CA 1 ATOM 6566 C C . SER B 1 332 ? 31.020 58.286 -7.114 1.00 14.38 ? 332 SER B C 1 ATOM 6567 O O . SER B 1 332 ? 29.811 58.489 -7.120 1.00 14.21 ? 332 SER B O 1 ATOM 6568 C CB . SER B 1 332 ? 32.117 56.221 -7.966 1.00 15.92 ? 332 SER B CB 1 ATOM 6569 O OG . SER B 1 332 ? 32.806 57.099 -8.835 1.00 17.43 ? 332 SER B OG 1 ATOM 6570 N N . LEU B 1 333 ? 31.914 59.201 -7.460 1.00 15.22 ? 333 LEU B N 1 ATOM 6571 C CA . LEU B 1 333 ? 31.520 60.515 -7.935 1.00 15.86 ? 333 LEU B CA 1 ATOM 6572 C C . LEU B 1 333 ? 31.047 60.276 -9.358 1.00 16.52 ? 333 LEU B C 1 ATOM 6573 O O . LEU B 1 333 ? 31.380 59.254 -9.960 1.00 16.66 ? 333 LEU B O 1 ATOM 6574 C CB . LEU B 1 333 ? 32.723 61.465 -7.946 1.00 16.09 ? 333 LEU B CB 1 ATOM 6575 C CG . LEU B 1 333 ? 33.348 61.860 -6.607 1.00 16.61 ? 333 LEU B CG 1 ATOM 6576 C CD1 . LEU B 1 333 ? 34.662 62.581 -6.851 1.00 18.72 ? 333 LEU B CD1 1 ATOM 6577 C CD2 . LEU B 1 333 ? 32.382 62.735 -5.841 1.00 18.03 ? 333 LEU B CD2 1 ATOM 6578 N N . PRO B 1 334 ? 30.269 61.215 -9.925 1.00 16.89 ? 334 PRO B N 1 ATOM 6579 C CA . PRO B 1 334 ? 29.793 61.017 -11.300 1.00 17.77 ? 334 PRO B CA 1 ATOM 6580 C C . PRO B 1 334 ? 30.946 60.889 -12.292 1.00 18.07 ? 334 PRO B C 1 ATOM 6581 O O . PRO B 1 334 ? 32.062 61.336 -12.022 1.00 18.81 ? 334 PRO B O 1 ATOM 6582 C CB . PRO B 1 334 ? 28.930 62.256 -11.559 1.00 18.37 ? 334 PRO B CB 1 ATOM 6583 C CG . PRO B 1 334 ? 29.547 63.319 -10.647 1.00 17.96 ? 334 PRO B CG 1 ATOM 6584 C CD . PRO B 1 334 ? 29.826 62.515 -9.383 1.00 18.02 ? 334 PRO B CD 1 ATOM 6585 N N . PHE B 1 335 ? 30.672 60.270 -13.436 1.00 18.56 ? 335 PHE B N 1 ATOM 6586 C CA . PHE B 1 335 ? 31.666 60.088 -14.490 1.00 19.29 ? 335 PHE B CA 1 ATOM 6587 C C . PHE B 1 335 ? 31.534 61.193 -15.535 1.00 19.85 ? 335 PHE B C 1 ATOM 6588 O O . PHE B 1 335 ? 30.476 61.352 -16.145 1.00 19.86 ? 335 PHE B O 1 ATOM 6589 C CB . PHE B 1 335 ? 31.464 58.739 -15.191 1.00 17.72 ? 335 PHE B CB 1 ATOM 6590 C CG . PHE B 1 335 ? 31.727 57.535 -14.320 1.00 15.66 ? 335 PHE B CG 1 ATOM 6591 C CD1 . PHE B 1 335 ? 31.287 56.276 -14.730 1.00 15.01 ? 335 PHE B CD1 1 ATOM 6592 C CD2 . PHE B 1 335 ? 32.435 57.639 -13.122 1.00 16.37 ? 335 PHE B CD2 1 ATOM 6593 C CE1 . PHE B 1 335 ? 31.543 55.122 -13.962 1.00 14.56 ? 335 PHE B CE1 1 ATOM 6594 C CE2 . PHE B 1 335 ? 32.701 56.497 -12.338 1.00 14.55 ? 335 PHE B CE2 1 ATOM 6595 C CZ . PHE B 1 335 ? 32.255 55.232 -12.761 1.00 14.76 ? 335 PHE B CZ 1 ATOM 6596 N N . THR B 1 336 ? 32.607 61.944 -15.759 1.00 21.88 ? 336 THR B N 1 ATOM 6597 C CA . THR B 1 336 ? 32.586 63.011 -16.757 1.00 21.85 ? 336 THR B CA 1 ATOM 6598 C C . THR B 1 336 ? 32.802 62.404 -18.138 1.00 20.73 ? 336 THR B C 1 ATOM 6599 O O . THR B 1 336 ? 32.193 62.824 -19.122 1.00 21.55 ? 336 THR B O 1 ATOM 6600 C CB . THR B 1 336 ? 33.677 64.063 -16.489 1.00 23.86 ? 336 THR B CB 1 ATOM 6601 O OG1 . THR B 1 336 ? 34.958 63.426 -16.386 1.00 26.11 ? 336 THR B OG1 1 ATOM 6602 C CG2 . THR B 1 336 ? 33.378 64.812 -15.207 1.00 25.56 ? 336 THR B CG2 1 ATOM 6603 N N . THR B 1 337 ? 33.685 61.415 -18.192 1.00 18.24 ? 337 THR B N 1 ATOM 6604 C CA . THR B 1 337 ? 33.987 60.681 -19.415 1.00 16.83 ? 337 THR B CA 1 ATOM 6605 C C . THR B 1 337 ? 33.908 59.209 -19.006 1.00 16.29 ? 337 THR B C 1 ATOM 6606 O O . THR B 1 337 ? 34.023 58.889 -17.826 1.00 14.80 ? 337 THR B O 1 ATOM 6607 C CB . THR B 1 337 ? 35.389 61.009 -19.949 1.00 17.68 ? 337 THR B CB 1 ATOM 6608 O OG1 . THR B 1 337 ? 36.369 60.641 -18.977 1.00 18.69 ? 337 THR B OG1 1 ATOM 6609 C CG2 . THR B 1 337 ? 35.503 62.502 -20.251 1.00 18.18 ? 337 THR B CG2 1 ATOM 6610 N N . PRO B 1 338 ? 33.729 58.296 -19.972 1.00 15.98 ? 338 PRO B N 1 ATOM 6611 C CA . PRO B 1 338 ? 33.628 56.872 -19.629 1.00 15.59 ? 338 PRO B CA 1 ATOM 6612 C C . PRO B 1 338 ? 34.891 56.168 -19.158 1.00 13.65 ? 338 PRO B C 1 ATOM 6613 O O . PRO B 1 338 ? 35.943 56.270 -19.790 1.00 12.97 ? 338 PRO B O 1 ATOM 6614 C CB . PRO B 1 338 ? 33.116 56.228 -20.921 1.00 15.67 ? 338 PRO B CB 1 ATOM 6615 C CG . PRO B 1 338 ? 32.675 57.415 -21.811 1.00 18.92 ? 338 PRO B CG 1 ATOM 6616 C CD . PRO B 1 338 ? 33.659 58.483 -21.429 1.00 16.91 ? 338 PRO B CD 1 ATOM 6617 N N . PRO B 1 339 ? 34.812 55.463 -18.020 1.00 13.52 ? 339 PRO B N 1 ATOM 6618 C CA . PRO B 1 339 ? 35.997 54.745 -17.542 1.00 12.61 ? 339 PRO B CA 1 ATOM 6619 C C . PRO B 1 339 ? 35.920 53.446 -18.344 1.00 12.33 ? 339 PRO B C 1 ATOM 6620 O O . PRO B 1 339 ? 35.038 52.621 -18.104 1.00 12.36 ? 339 PRO B O 1 ATOM 6621 C CB . PRO B 1 339 ? 35.696 54.516 -16.060 1.00 13.96 ? 339 PRO B CB 1 ATOM 6622 C CG . PRO B 1 339 ? 34.710 55.601 -15.722 1.00 14.38 ? 339 PRO B CG 1 ATOM 6623 C CD . PRO B 1 339 ? 33.825 55.606 -16.940 1.00 13.82 ? 339 PRO B CD 1 ATOM 6624 N N . PHE B 1 340 ? 36.821 53.269 -19.303 1.00 11.61 ? 340 PHE B N 1 ATOM 6625 C CA . PHE B 1 340 ? 36.779 52.078 -20.143 1.00 11.38 ? 340 PHE B CA 1 ATOM 6626 C C . PHE B 1 340 ? 36.767 50.768 -19.365 1.00 10.47 ? 340 PHE B C 1 ATOM 6627 O O . PHE B 1 340 ? 37.602 50.542 -18.490 1.00 11.34 ? 340 PHE B O 1 ATOM 6628 C CB . PHE B 1 340 ? 37.948 52.071 -21.128 1.00 11.62 ? 340 PHE B CB 1 ATOM 6629 C CG . PHE B 1 340 ? 37.734 51.161 -22.301 1.00 11.31 ? 340 PHE B CG 1 ATOM 6630 C CD1 . PHE B 1 340 ? 36.944 51.565 -23.374 1.00 12.15 ? 340 PHE B CD1 1 ATOM 6631 C CD2 . PHE B 1 340 ? 38.296 49.889 -22.324 1.00 10.57 ? 340 PHE B CD2 1 ATOM 6632 C CE1 . PHE B 1 340 ? 36.716 50.715 -24.454 1.00 11.49 ? 340 PHE B CE1 1 ATOM 6633 C CE2 . PHE B 1 340 ? 38.075 49.031 -23.397 1.00 10.78 ? 340 PHE B CE2 1 ATOM 6634 C CZ . PHE B 1 340 ? 37.282 49.444 -24.467 1.00 10.64 ? 340 PHE B CZ 1 ATOM 6635 N N . GLY B 1 341 ? 35.813 49.905 -19.702 1.00 10.67 ? 341 GLY B N 1 ATOM 6636 C CA . GLY B 1 341 ? 35.708 48.622 -19.034 1.00 10.18 ? 341 GLY B CA 1 ATOM 6637 C C . GLY B 1 341 ? 34.728 48.603 -17.876 1.00 10.61 ? 341 GLY B C 1 ATOM 6638 O O . GLY B 1 341 ? 34.245 47.537 -17.498 1.00 10.38 ? 341 GLY B O 1 ATOM 6639 N N . PHE B 1 342 ? 34.425 49.767 -17.305 1.00 11.04 ? 342 PHE B N 1 ATOM 6640 C CA . PHE B 1 342 ? 33.491 49.810 -16.183 1.00 10.36 ? 342 PHE B CA 1 ATOM 6641 C C . PHE B 1 342 ? 32.128 49.345 -16.683 1.00 10.75 ? 342 PHE B C 1 ATOM 6642 O O . PHE B 1 342 ? 31.495 48.469 -16.094 1.00 11.01 ? 342 PHE B O 1 ATOM 6643 C CB . PHE B 1 342 ? 33.385 51.220 -15.603 1.00 11.53 ? 342 PHE B CB 1 ATOM 6644 C CG . PHE B 1 342 ? 32.782 51.249 -14.228 1.00 11.93 ? 342 PHE B CG 1 ATOM 6645 C CD1 . PHE B 1 342 ? 33.573 51.032 -13.102 1.00 13.21 ? 342 PHE B CD1 1 ATOM 6646 C CD2 . PHE B 1 342 ? 31.412 51.414 -14.063 1.00 12.10 ? 342 PHE B CD2 1 ATOM 6647 C CE1 . PHE B 1 342 ? 33.004 50.974 -11.831 1.00 13.47 ? 342 PHE B CE1 1 ATOM 6648 C CE2 . PHE B 1 342 ? 30.832 51.356 -12.798 1.00 12.96 ? 342 PHE B CE2 1 ATOM 6649 C CZ . PHE B 1 342 ? 31.631 51.134 -11.679 1.00 13.79 ? 342 PHE B CZ 1 ATOM 6650 N N . PHE B 1 343 ? 31.673 49.954 -17.769 1.00 10.97 ? 343 PHE B N 1 ATOM 6651 C CA . PHE B 1 343 ? 30.423 49.561 -18.393 1.00 11.12 ? 343 PHE B CA 1 ATOM 6652 C C . PHE B 1 343 ? 30.897 48.764 -19.614 1.00 11.65 ? 343 PHE B C 1 ATOM 6653 O O . PHE B 1 343 ? 31.976 49.029 -20.150 1.00 9.95 ? 343 PHE B O 1 ATOM 6654 C CB . PHE B 1 343 ? 29.606 50.809 -18.736 1.00 11.75 ? 343 PHE B CB 1 ATOM 6655 C CG . PHE B 1 343 ? 29.105 51.542 -17.512 1.00 13.44 ? 343 PHE B CG 1 ATOM 6656 C CD1 . PHE B 1 343 ? 29.267 52.918 -17.382 1.00 14.34 ? 343 PHE B CD1 1 ATOM 6657 C CD2 . PHE B 1 343 ? 28.492 50.841 -16.473 1.00 14.26 ? 343 PHE B CD2 1 ATOM 6658 C CE1 . PHE B 1 343 ? 28.827 53.585 -16.231 1.00 16.07 ? 343 PHE B CE1 1 ATOM 6659 C CE2 . PHE B 1 343 ? 28.050 51.495 -15.322 1.00 14.41 ? 343 PHE B CE2 1 ATOM 6660 C CZ . PHE B 1 343 ? 28.219 52.871 -15.202 1.00 14.86 ? 343 PHE B CZ 1 ATOM 6661 N N . PRO B 1 344 ? 30.114 47.767 -20.058 1.00 12.32 ? 344 PRO B N 1 ATOM 6662 C CA . PRO B 1 344 ? 30.480 46.920 -21.201 1.00 11.98 ? 344 PRO B CA 1 ATOM 6663 C C . PRO B 1 344 ? 30.675 47.528 -22.590 1.00 13.30 ? 344 PRO B C 1 ATOM 6664 O O . PRO B 1 344 ? 31.369 46.938 -23.425 1.00 10.54 ? 344 PRO B O 1 ATOM 6665 C CB . PRO B 1 344 ? 29.402 45.839 -21.176 1.00 12.95 ? 344 PRO B CB 1 ATOM 6666 C CG . PRO B 1 344 ? 28.209 46.586 -20.692 1.00 11.94 ? 344 PRO B CG 1 ATOM 6667 C CD . PRO B 1 344 ? 28.775 47.412 -19.555 1.00 12.39 ? 344 PRO B CD 1 ATOM 6668 N N . SER B 1 345 ? 30.074 48.692 -22.827 1.00 13.85 ? 345 SER B N 1 ATOM 6669 C CA . SER B 1 345 ? 30.180 49.385 -24.110 1.00 18.02 ? 345 SER B CA 1 ATOM 6670 C C . SER B 1 345 ? 30.420 50.870 -23.885 1.00 18.43 ? 345 SER B C 1 ATOM 6671 O O . SER B 1 345 ? 30.105 51.409 -22.831 1.00 18.56 ? 345 SER B O 1 ATOM 6672 C CB . SER B 1 345 ? 28.898 49.205 -24.923 1.00 18.97 ? 345 SER B CB 1 ATOM 6673 O OG . SER B 1 345 ? 28.536 47.838 -24.986 1.00 23.62 ? 345 SER B OG 1 ATOM 6674 N N . SER B 1 346 ? 30.967 51.539 -24.888 1.00 21.46 ? 346 SER B N 1 ATOM 6675 C CA . SER B 1 346 ? 31.248 52.963 -24.776 1.00 23.64 ? 346 SER B CA 1 ATOM 6676 C C . SER B 1 346 ? 30.011 53.860 -24.915 1.00 25.39 ? 346 SER B C 1 ATOM 6677 O O . SER B 1 346 ? 30.074 55.055 -24.619 1.00 25.75 ? 346 SER B O 1 ATOM 6678 C CB . SER B 1 346 ? 32.291 53.367 -25.820 1.00 24.50 ? 346 SER B CB 1 ATOM 6679 O OG . SER B 1 346 ? 31.825 53.127 -27.136 1.00 26.45 ? 346 SER B OG 1 ATOM 6680 N N . SER B 1 347 ? 28.887 53.294 -25.348 1.00 25.52 ? 347 SER B N 1 ATOM 6681 C CA . SER B 1 347 ? 27.672 54.083 -25.533 1.00 26.45 ? 347 SER B CA 1 ATOM 6682 C C . SER B 1 347 ? 26.768 54.088 -24.309 1.00 25.43 ? 347 SER B C 1 ATOM 6683 O O . SER B 1 347 ? 25.631 54.534 -24.378 1.00 27.08 ? 347 SER B O 1 ATOM 6684 C CB . SER B 1 347 ? 26.886 53.565 -26.742 1.00 27.09 ? 347 SER B CB 1 ATOM 6685 O OG . SER B 1 347 ? 26.328 52.292 -26.486 1.00 29.55 ? 347 SER B OG 1 ATOM 6686 N N . TYR B 1 348 ? 27.278 53.592 -23.188 1.00 23.35 ? 348 TYR B N 1 ATOM 6687 C CA . TYR B 1 348 ? 26.512 53.522 -21.941 1.00 20.61 ? 348 TYR B CA 1 ATOM 6688 C C . TYR B 1 348 ? 26.254 54.920 -21.361 1.00 19.99 ? 348 TYR B C 1 ATOM 6689 O O . TYR B 1 348 ? 27.116 55.791 -21.427 1.00 18.65 ? 348 TYR B O 1 ATOM 6690 C CB . TYR B 1 348 ? 27.288 52.690 -20.916 1.00 18.98 ? 348 TYR B CB 1 ATOM 6691 C CG . TYR B 1 348 ? 26.444 52.101 -19.817 1.00 17.37 ? 348 TYR B CG 1 ATOM 6692 C CD1 . TYR B 1 348 ? 25.904 50.821 -19.941 1.00 17.20 ? 348 TYR B CD1 1 ATOM 6693 C CD2 . TYR B 1 348 ? 26.203 52.811 -18.646 1.00 17.62 ? 348 TYR B CD2 1 ATOM 6694 C CE1 . TYR B 1 348 ? 25.145 50.258 -18.916 1.00 14.77 ? 348 TYR B CE1 1 ATOM 6695 C CE2 . TYR B 1 348 ? 25.447 52.262 -17.618 1.00 15.93 ? 348 TYR B CE2 1 ATOM 6696 C CZ . TYR B 1 348 ? 24.923 50.986 -17.761 1.00 14.77 ? 348 TYR B CZ 1 ATOM 6697 O OH . TYR B 1 348 ? 24.174 50.444 -16.751 1.00 12.44 ? 348 TYR B OH 1 ATOM 6698 N N . PRO B 1 349 ? 25.059 55.154 -20.788 1.00 19.95 ? 349 PRO B N 1 ATOM 6699 C CA . PRO B 1 349 ? 24.752 56.470 -20.210 1.00 20.01 ? 349 PRO B CA 1 ATOM 6700 C C . PRO B 1 349 ? 25.585 56.702 -18.948 1.00 19.49 ? 349 PRO B C 1 ATOM 6701 O O . PRO B 1 349 ? 25.662 55.829 -18.088 1.00 20.41 ? 349 PRO B O 1 ATOM 6702 C CB . PRO B 1 349 ? 23.258 56.372 -19.917 1.00 20.59 ? 349 PRO B CB 1 ATOM 6703 C CG . PRO B 1 349 ? 23.083 54.915 -19.591 1.00 20.59 ? 349 PRO B CG 1 ATOM 6704 C CD . PRO B 1 349 ? 23.903 54.248 -20.671 1.00 20.14 ? 349 PRO B CD 1 ATOM 6705 N N . LEU B 1 350 ? 26.207 57.872 -18.841 1.00 18.10 ? 350 LEU B N 1 ATOM 6706 C CA . LEU B 1 350 ? 27.049 58.174 -17.686 1.00 18.18 ? 350 LEU B CA 1 ATOM 6707 C C . LEU B 1 350 ? 26.297 58.805 -16.521 1.00 18.43 ? 350 LEU B C 1 ATOM 6708 O O . LEU B 1 350 ? 25.340 59.549 -16.714 1.00 17.72 ? 350 LEU B O 1 ATOM 6709 C CB . LEU B 1 350 ? 28.197 59.100 -18.095 1.00 18.27 ? 350 LEU B CB 1 ATOM 6710 C CG . LEU B 1 350 ? 29.151 58.584 -19.174 1.00 18.99 ? 350 LEU B CG 1 ATOM 6711 C CD1 . LEU B 1 350 ? 30.220 59.629 -19.435 1.00 19.43 ? 350 LEU B CD1 1 ATOM 6712 C CD2 . LEU B 1 350 ? 29.787 57.273 -18.727 1.00 18.91 ? 350 LEU B CD2 1 ATOM 6713 N N . PRO B 1 351 ? 26.725 58.509 -15.286 1.00 18.74 ? 351 PRO B N 1 ATOM 6714 C CA . PRO B 1 351 ? 26.073 59.070 -14.100 1.00 19.21 ? 351 PRO B CA 1 ATOM 6715 C C . PRO B 1 351 ? 26.463 60.538 -13.916 1.00 20.51 ? 351 PRO B C 1 ATOM 6716 O O . PRO B 1 351 ? 27.650 60.861 -13.869 1.00 20.13 ? 351 PRO B O 1 ATOM 6717 C CB . PRO B 1 351 ? 26.597 58.183 -12.976 1.00 18.84 ? 351 PRO B CB 1 ATOM 6718 C CG . PRO B 1 351 ? 27.983 57.868 -13.433 1.00 19.06 ? 351 PRO B CG 1 ATOM 6719 C CD . PRO B 1 351 ? 27.787 57.560 -14.904 1.00 19.36 ? 351 PRO B CD 1 ATOM 6720 N N . ASN B 1 352 ? 25.472 61.421 -13.812 1.00 21.43 ? 352 ASN B N 1 ATOM 6721 C CA . ASN B 1 352 ? 25.752 62.846 -13.647 1.00 24.04 ? 352 ASN B CA 1 ATOM 6722 C C . ASN B 1 352 ? 25.771 63.286 -12.177 1.00 22.88 ? 352 ASN B C 1 ATOM 6723 O O . ASN B 1 352 ? 25.925 64.466 -11.876 1.00 23.80 ? 352 ASN B O 1 ATOM 6724 C CB . ASN B 1 352 ? 24.746 63.690 -14.470 1.00 27.13 ? 352 ASN B CB 1 ATOM 6725 C CG . ASN B 1 352 ? 23.310 63.581 -13.961 1.00 31.81 ? 352 ASN B CG 1 ATOM 6726 O OD1 . ASN B 1 352 ? 23.093 63.170 -12.816 1.00 31.66 ? 352 ASN B OD1 1 ATOM 6727 N ND2 . ASN B 1 352 ? 22.326 63.990 -14.774 1.00 36.27 ? 352 ASN B ND2 1 ATOM 6728 N N . SER B 1 353 ? 25.625 62.328 -11.268 1.00 21.22 ? 353 SER B N 1 ATOM 6729 C CA . SER B 1 353 ? 25.651 62.603 -9.830 1.00 20.11 ? 353 SER B CA 1 ATOM 6730 C C . SER B 1 353 ? 26.280 61.406 -9.118 1.00 19.08 ? 353 SER B C 1 ATOM 6731 O O . SER B 1 353 ? 26.607 60.413 -9.767 1.00 17.36 ? 353 SER B O 1 ATOM 6732 C CB . SER B 1 353 ? 24.233 62.846 -9.304 1.00 22.37 ? 353 SER B CB 1 ATOM 6733 O OG . SER B 1 353 ? 23.408 61.711 -9.506 1.00 25.74 ? 353 SER B OG 1 ATOM 6734 N N . THR B 1 354 ? 26.457 61.488 -7.799 1.00 17.01 ? 354 THR B N 1 ATOM 6735 C CA . THR B 1 354 ? 27.056 60.369 -7.067 1.00 16.64 ? 354 THR B CA 1 ATOM 6736 C C . THR B 1 354 ? 26.157 59.153 -7.240 1.00 15.72 ? 354 THR B C 1 ATOM 6737 O O . THR B 1 354 ? 24.938 59.287 -7.333 1.00 17.13 ? 354 THR B O 1 ATOM 6738 C CB . THR B 1 354 ? 27.225 60.669 -5.553 1.00 16.96 ? 354 THR B CB 1 ATOM 6739 O OG1 . THR B 1 354 ? 25.946 60.945 -4.965 1.00 17.25 ? 354 THR B OG1 1 ATOM 6740 C CG2 . THR B 1 354 ? 28.152 61.862 -5.345 1.00 17.67 ? 354 THR B CG2 1 ATOM 6741 N N . PHE B 1 355 ? 26.752 57.966 -7.294 1.00 14.48 ? 355 PHE B N 1 ATOM 6742 C CA . PHE B 1 355 ? 25.961 56.759 -7.486 1.00 13.41 ? 355 PHE B CA 1 ATOM 6743 C C . PHE B 1 355 ? 26.584 55.537 -6.827 1.00 11.53 ? 355 PHE B C 1 ATOM 6744 O O . PHE B 1 355 ? 27.746 55.559 -6.424 1.00 11.09 ? 355 PHE B O 1 ATOM 6745 C CB . PHE B 1 355 ? 25.772 56.498 -8.989 1.00 14.15 ? 355 PHE B CB 1 ATOM 6746 C CG . PHE B 1 355 ? 26.991 55.932 -9.678 1.00 13.27 ? 355 PHE B CG 1 ATOM 6747 C CD1 . PHE B 1 355 ? 27.033 54.588 -10.046 1.00 15.60 ? 355 PHE B CD1 1 ATOM 6748 C CD2 . PHE B 1 355 ? 28.089 56.739 -9.966 1.00 14.47 ? 355 PHE B CD2 1 ATOM 6749 C CE1 . PHE B 1 355 ? 28.153 54.056 -10.695 1.00 16.45 ? 355 PHE B CE1 1 ATOM 6750 C CE2 . PHE B 1 355 ? 29.213 56.218 -10.614 1.00 16.55 ? 355 PHE B CE2 1 ATOM 6751 C CZ . PHE B 1 355 ? 29.243 54.873 -10.979 1.00 16.90 ? 355 PHE B CZ 1 ATOM 6752 N N . ALA B 1 356 ? 25.789 54.479 -6.712 1.00 10.67 ? 356 ALA B N 1 ATOM 6753 C CA . ALA B 1 356 ? 26.247 53.223 -6.128 1.00 10.41 ? 356 ALA B CA 1 ATOM 6754 C C . ALA B 1 356 ? 26.101 52.127 -7.174 1.00 10.98 ? 356 ALA B C 1 ATOM 6755 O O . ALA B 1 356 ? 25.064 52.011 -7.826 1.00 10.71 ? 356 ALA B O 1 ATOM 6756 C CB . ALA B 1 356 ? 25.429 52.881 -4.890 1.00 11.54 ? 356 ALA B CB 1 ATOM 6757 N N . HIS B 1 357 ? 27.155 51.333 -7.320 1.00 10.09 ? 357 HIS B N 1 ATOM 6758 C CA . HIS B 1 357 ? 27.217 50.239 -8.283 1.00 9.88 ? 357 HIS B CA 1 ATOM 6759 C C . HIS B 1 357 ? 27.173 48.910 -7.527 1.00 10.93 ? 357 HIS B C 1 ATOM 6760 O O . HIS B 1 357 ? 28.167 48.507 -6.925 1.00 12.28 ? 357 HIS B O 1 ATOM 6761 C CB . HIS B 1 357 ? 28.532 50.363 -9.066 1.00 9.67 ? 357 HIS B CB 1 ATOM 6762 C CG . HIS B 1 357 ? 28.748 49.312 -10.115 1.00 9.81 ? 357 HIS B CG 1 ATOM 6763 N ND1 . HIS B 1 357 ? 28.105 49.328 -11.334 1.00 9.89 ? 357 HIS B ND1 1 ATOM 6764 C CD2 . HIS B 1 357 ? 29.603 48.262 -10.155 1.00 10.14 ? 357 HIS B CD2 1 ATOM 6765 C CE1 . HIS B 1 357 ? 28.558 48.337 -12.082 1.00 11.16 ? 357 HIS B CE1 1 ATOM 6766 N NE2 . HIS B 1 357 ? 29.469 47.676 -11.391 1.00 10.70 ? 357 HIS B NE2 1 ATOM 6767 N N . PHE B 1 358 ? 26.020 48.247 -7.534 1.00 8.98 ? 358 PHE B N 1 ATOM 6768 C CA . PHE B 1 358 ? 25.895 46.953 -6.873 1.00 10.13 ? 358 PHE B CA 1 ATOM 6769 C C . PHE B 1 358 ? 26.275 45.907 -7.911 1.00 9.97 ? 358 PHE B C 1 ATOM 6770 O O . PHE B 1 358 ? 25.579 45.737 -8.915 1.00 10.56 ? 358 PHE B O 1 ATOM 6771 C CB . PHE B 1 358 ? 24.464 46.715 -6.377 1.00 9.49 ? 358 PHE B CB 1 ATOM 6772 C CG . PHE B 1 358 ? 24.099 47.534 -5.174 1.00 9.91 ? 358 PHE B CG 1 ATOM 6773 C CD1 . PHE B 1 358 ? 23.599 48.823 -5.317 1.00 11.98 ? 358 PHE B CD1 1 ATOM 6774 C CD2 . PHE B 1 358 ? 24.288 47.026 -3.891 1.00 12.36 ? 358 PHE B CD2 1 ATOM 6775 C CE1 . PHE B 1 358 ? 23.291 49.598 -4.197 1.00 12.44 ? 358 PHE B CE1 1 ATOM 6776 C CE2 . PHE B 1 358 ? 23.984 47.792 -2.765 1.00 12.60 ? 358 PHE B CE2 1 ATOM 6777 C CZ . PHE B 1 358 ? 23.485 49.081 -2.920 1.00 12.32 ? 358 PHE B CZ 1 ATOM 6778 N N . ALA B 1 359 ? 27.385 45.214 -7.667 1.00 9.42 ? 359 ALA B N 1 ATOM 6779 C CA . ALA B 1 359 ? 27.888 44.219 -8.605 1.00 9.13 ? 359 ALA B CA 1 ATOM 6780 C C . ALA B 1 359 ? 27.833 42.784 -8.093 1.00 9.46 ? 359 ALA B C 1 ATOM 6781 O O . ALA B 1 359 ? 27.981 42.522 -6.896 1.00 9.21 ? 359 ALA B O 1 ATOM 6782 C CB . ALA B 1 359 ? 29.315 44.573 -9.003 1.00 10.01 ? 359 ALA B CB 1 ATOM 6783 N N . SER B 1 360 ? 27.625 41.860 -9.026 1.00 8.22 ? 360 SER B N 1 ATOM 6784 C CA . SER B 1 360 ? 27.541 40.437 -8.715 1.00 8.43 ? 360 SER B CA 1 ATOM 6785 C C . SER B 1 360 ? 28.439 39.654 -9.677 1.00 8.86 ? 360 SER B C 1 ATOM 6786 O O . SER B 1 360 ? 28.326 39.787 -10.900 1.00 8.60 ? 360 SER B O 1 ATOM 6787 C CB . SER B 1 360 ? 26.084 39.972 -8.837 1.00 8.93 ? 360 SER B CB 1 ATOM 6788 O OG . SER B 1 360 ? 25.925 38.611 -8.464 1.00 8.70 ? 360 SER B OG 1 ATOM 6789 N N . LYS B 1 361 ? 29.336 38.850 -9.111 1.00 8.23 ? 361 LYS B N 1 ATOM 6790 C CA . LYS B 1 361 ? 30.281 38.044 -9.887 1.00 8.08 ? 361 LYS B CA 1 ATOM 6791 C C . LYS B 1 361 ? 29.931 36.561 -9.790 1.00 7.78 ? 361 LYS B C 1 ATOM 6792 O O . LYS B 1 361 ? 29.824 36.018 -8.695 1.00 8.82 ? 361 LYS B O 1 ATOM 6793 C CB . LYS B 1 361 ? 31.708 38.259 -9.357 1.00 10.45 ? 361 LYS B CB 1 ATOM 6794 C CG . LYS B 1 361 ? 32.782 37.377 -10.008 1.00 9.35 ? 361 LYS B CG 1 ATOM 6795 C CD . LYS B 1 361 ? 34.142 37.575 -9.333 1.00 10.90 ? 361 LYS B CD 1 ATOM 6796 C CE . LYS B 1 361 ? 35.179 36.591 -9.855 1.00 10.66 ? 361 LYS B CE 1 ATOM 6797 N NZ . LYS B 1 361 ? 36.481 36.682 -9.117 1.00 9.66 ? 361 LYS B NZ 1 ATOM 6798 N N . VAL B 1 362 ? 29.745 35.910 -10.935 1.00 7.43 ? 362 VAL B N 1 ATOM 6799 C CA . VAL B 1 362 ? 29.432 34.486 -10.947 1.00 6.58 ? 362 VAL B CA 1 ATOM 6800 C C . VAL B 1 362 ? 30.704 33.686 -10.660 1.00 7.94 ? 362 VAL B C 1 ATOM 6801 O O . VAL B 1 362 ? 31.770 33.977 -11.208 1.00 7.35 ? 362 VAL B O 1 ATOM 6802 C CB . VAL B 1 362 ? 28.841 34.052 -12.313 1.00 6.73 ? 362 VAL B CB 1 ATOM 6803 C CG1 . VAL B 1 362 ? 28.700 32.532 -12.373 1.00 7.27 ? 362 VAL B CG1 1 ATOM 6804 C CG2 . VAL B 1 362 ? 27.482 34.704 -12.513 1.00 7.97 ? 362 VAL B CG2 1 ATOM 6805 N N . ALA B 1 363 ? 30.589 32.694 -9.782 1.00 7.82 ? 363 ALA B N 1 ATOM 6806 C CA . ALA B 1 363 ? 31.722 31.848 -9.413 1.00 8.64 ? 363 ALA B CA 1 ATOM 6807 C C . ALA B 1 363 ? 32.219 31.033 -10.608 1.00 7.86 ? 363 ALA B C 1 ATOM 6808 O O . ALA B 1 363 ? 31.479 30.801 -11.561 1.00 7.53 ? 363 ALA B O 1 ATOM 6809 C CB . ALA B 1 363 ? 31.316 30.914 -8.277 1.00 9.00 ? 363 ALA B CB 1 ATOM 6810 N N . GLY B 1 364 ? 33.473 30.595 -10.549 1.00 8.18 ? 364 GLY B N 1 ATOM 6811 C CA . GLY B 1 364 ? 34.036 29.809 -11.637 1.00 7.56 ? 364 GLY B CA 1 ATOM 6812 C C . GLY B 1 364 ? 34.867 30.664 -12.576 1.00 7.82 ? 364 GLY B C 1 ATOM 6813 O O . GLY B 1 364 ? 35.982 31.063 -12.229 1.00 7.67 ? 364 GLY B O 1 ATOM 6814 N N . PRO B 1 365 ? 34.368 30.943 -13.788 1.00 7.14 ? 365 PRO B N 1 ATOM 6815 C CA . PRO B 1 365 ? 33.080 30.498 -14.329 1.00 7.93 ? 365 PRO B CA 1 ATOM 6816 C C . PRO B 1 365 ? 33.288 29.174 -15.054 1.00 7.87 ? 365 PRO B C 1 ATOM 6817 O O . PRO B 1 365 ? 34.423 28.805 -15.358 1.00 8.79 ? 365 PRO B O 1 ATOM 6818 C CB . PRO B 1 365 ? 32.726 31.614 -15.295 1.00 8.36 ? 365 PRO B CB 1 ATOM 6819 C CG . PRO B 1 365 ? 34.067 31.914 -15.905 1.00 8.07 ? 365 PRO B CG 1 ATOM 6820 C CD . PRO B 1 365 ? 35.002 31.917 -14.698 1.00 7.54 ? 365 PRO B CD 1 ATOM 6821 N N . LEU B 1 366 ? 32.200 28.467 -15.342 1.00 8.72 ? 366 LEU B N 1 ATOM 6822 C CA . LEU B 1 366 ? 32.298 27.194 -16.049 1.00 10.01 ? 366 LEU B CA 1 ATOM 6823 C C . LEU B 1 366 ? 32.535 27.419 -17.540 1.00 9.65 ? 366 LEU B C 1 ATOM 6824 O O . LEU B 1 366 ? 33.149 26.589 -18.215 1.00 11.00 ? 366 LEU B O 1 ATOM 6825 C CB . LEU B 1 366 ? 31.023 26.375 -15.834 1.00 9.94 ? 366 LEU B CB 1 ATOM 6826 C CG . LEU B 1 366 ? 30.808 25.892 -14.398 1.00 11.41 ? 366 LEU B CG 1 ATOM 6827 C CD1 . LEU B 1 366 ? 29.411 25.312 -14.253 1.00 11.50 ? 366 LEU B CD1 1 ATOM 6828 C CD2 . LEU B 1 366 ? 31.867 24.856 -14.042 1.00 12.40 ? 366 LEU B CD2 1 ATOM 6829 N N . SER B 1 367 ? 32.046 28.547 -18.048 1.00 9.64 ? 367 SER B N 1 ATOM 6830 C CA . SER B 1 367 ? 32.202 28.893 -19.458 1.00 8.23 ? 367 SER B CA 1 ATOM 6831 C C . SER B 1 367 ? 33.632 29.334 -19.735 1.00 9.16 ? 367 SER B C 1 ATOM 6832 O O . SER B 1 367 ? 34.287 29.911 -18.869 1.00 8.98 ? 367 SER B O 1 ATOM 6833 C CB . SER B 1 367 ? 31.258 30.039 -19.830 1.00 9.08 ? 367 SER B CB 1 ATOM 6834 O OG . SER B 1 367 ? 29.910 29.705 -19.557 1.00 8.96 ? 367 SER B OG 1 ATOM 6835 N N . TYR B 1 368 ? 34.112 29.068 -20.944 1.00 8.93 ? 368 TYR B N 1 ATOM 6836 C CA . TYR B 1 368 ? 35.462 29.464 -21.312 1.00 9.05 ? 368 TYR B CA 1 ATOM 6837 C C . TYR B 1 368 ? 35.607 29.623 -22.816 1.00 9.47 ? 368 TYR B C 1 ATOM 6838 O O . TYR B 1 368 ? 34.759 29.170 -23.595 1.00 8.61 ? 368 TYR B O 1 ATOM 6839 C CB . TYR B 1 368 ? 36.482 28.442 -20.797 1.00 9.99 ? 368 TYR B CB 1 ATOM 6840 C CG . TYR B 1 368 ? 36.354 27.072 -21.421 1.00 11.90 ? 368 TYR B CG 1 ATOM 6841 C CD1 . TYR B 1 368 ? 36.896 26.800 -22.680 1.00 12.05 ? 368 TYR B CD1 1 ATOM 6842 C CD2 . TYR B 1 368 ? 35.672 26.050 -20.763 1.00 14.52 ? 368 TYR B CD2 1 ATOM 6843 C CE1 . TYR B 1 368 ? 36.758 25.540 -23.267 1.00 15.11 ? 368 TYR B CE1 1 ATOM 6844 C CE2 . TYR B 1 368 ? 35.527 24.788 -21.341 1.00 15.83 ? 368 TYR B CE2 1 ATOM 6845 C CZ . TYR B 1 368 ? 36.071 24.542 -22.590 1.00 14.82 ? 368 TYR B CZ 1 ATOM 6846 O OH . TYR B 1 368 ? 35.922 23.297 -23.160 1.00 17.37 ? 368 TYR B OH 1 ATOM 6847 N N . GLY B 1 369 ? 36.689 30.285 -23.205 1.00 8.23 ? 369 GLY B N 1 ATOM 6848 C CA . GLY B 1 369 ? 36.985 30.510 -24.605 1.00 8.77 ? 369 GLY B CA 1 ATOM 6849 C C . GLY B 1 369 ? 38.464 30.292 -24.852 1.00 9.62 ? 369 GLY B C 1 ATOM 6850 O O . GLY B 1 369 ? 39.105 29.502 -24.156 1.00 10.48 ? 369 GLY B O 1 ATOM 6851 N N . SER B 1 370 ? 39.018 30.996 -25.831 1.00 8.42 ? 370 SER B N 1 ATOM 6852 C CA . SER B 1 370 ? 40.431 30.840 -26.147 1.00 9.09 ? 370 SER B CA 1 ATOM 6853 C C . SER B 1 370 ? 41.086 32.139 -26.592 1.00 9.17 ? 370 SER B C 1 ATOM 6854 O O . SER B 1 370 ? 40.416 33.137 -26.864 1.00 8.22 ? 370 SER B O 1 ATOM 6855 C CB . SER B 1 370 ? 40.611 29.790 -27.245 1.00 10.72 ? 370 SER B CB 1 ATOM 6856 O OG . SER B 1 370 ? 40.082 30.253 -28.474 1.00 13.69 ? 370 SER B OG 1 ATOM 6857 N N . LEU B 1 371 ? 42.411 32.104 -26.654 1.00 9.10 ? 371 LEU B N 1 ATOM 6858 C CA . LEU B 1 371 ? 43.200 33.248 -27.075 1.00 9.93 ? 371 LEU B CA 1 ATOM 6859 C C . LEU B 1 371 ? 43.951 32.895 -28.355 1.00 10.49 ? 371 LEU B C 1 ATOM 6860 O O . LEU B 1 371 ? 44.506 31.803 -28.475 1.00 10.66 ? 371 LEU B O 1 ATOM 6861 C CB . LEU B 1 371 ? 44.188 33.635 -25.967 1.00 10.06 ? 371 LEU B CB 1 ATOM 6862 C CG . LEU B 1 371 ? 45.188 34.773 -26.217 1.00 8.97 ? 371 LEU B CG 1 ATOM 6863 C CD1 . LEU B 1 371 ? 45.561 35.413 -24.888 1.00 10.29 ? 371 LEU B CD1 1 ATOM 6864 C CD2 . LEU B 1 371 ? 46.426 34.249 -26.940 1.00 8.74 ? 371 LEU B CD2 1 ATOM 6865 N N . THR B 1 372 ? 43.943 33.817 -29.313 1.00 9.56 ? 372 THR B N 1 ATOM 6866 C CA . THR B 1 372 ? 44.643 33.633 -30.583 1.00 10.36 ? 372 THR B CA 1 ATOM 6867 C C . THR B 1 372 ? 45.399 34.921 -30.901 1.00 8.90 ? 372 THR B C 1 ATOM 6868 O O . THR B 1 372 ? 45.032 35.998 -30.428 1.00 9.83 ? 372 THR B O 1 ATOM 6869 C CB . THR B 1 372 ? 43.664 33.337 -31.744 1.00 12.25 ? 372 THR B CB 1 ATOM 6870 O OG1 . THR B 1 372 ? 42.684 34.380 -31.824 1.00 15.50 ? 372 THR B OG1 1 ATOM 6871 C CG2 . THR B 1 372 ? 42.965 32.001 -31.533 1.00 14.22 ? 372 THR B CG2 1 ATOM 6872 N N . LEU B 1 373 ? 46.456 34.813 -31.695 1.00 8.42 ? 373 LEU B N 1 ATOM 6873 C CA . LEU B 1 373 ? 47.246 35.987 -32.057 1.00 9.17 ? 373 LEU B CA 1 ATOM 6874 C C . LEU B 1 373 ? 46.541 36.863 -33.090 1.00 11.18 ? 373 LEU B C 1 ATOM 6875 O O . LEU B 1 373 ? 45.815 36.362 -33.949 1.00 11.64 ? 373 LEU B O 1 ATOM 6876 C CB . LEU B 1 373 ? 48.602 35.552 -32.620 1.00 8.55 ? 373 LEU B CB 1 ATOM 6877 C CG . LEU B 1 373 ? 49.485 34.710 -31.698 1.00 8.17 ? 373 LEU B CG 1 ATOM 6878 C CD1 . LEU B 1 373 ? 50.711 34.234 -32.466 1.00 8.43 ? 373 LEU B CD1 1 ATOM 6879 C CD2 . LEU B 1 373 ? 49.888 35.531 -30.482 1.00 9.69 ? 373 LEU B CD2 1 ATOM 6880 N N . LYS B 1 374 ? 46.754 38.175 -32.993 1.00 13.00 ? 374 LYS B N 1 ATOM 6881 C CA . LYS B 1 374 ? 46.183 39.129 -33.942 1.00 14.15 ? 374 LYS B CA 1 ATOM 6882 C C . LYS B 1 374 ? 47.326 39.523 -34.876 1.00 14.25 ? 374 LYS B C 1 ATOM 6883 O O . LYS B 1 374 ? 47.111 40.054 -35.966 1.00 17.17 ? 374 LYS B O 1 ATOM 6884 C CB . LYS B 1 374 ? 45.649 40.366 -33.218 1.00 16.95 ? 374 LYS B CB 1 ATOM 6885 C CG . LYS B 1 374 ? 44.919 41.363 -34.117 1.00 23.92 ? 374 LYS B CG 1 ATOM 6886 C CD . LYS B 1 374 ? 43.647 40.761 -34.707 1.00 28.19 ? 374 LYS B CD 1 ATOM 6887 C CE . LYS B 1 374 ? 42.766 41.824 -35.359 1.00 30.66 ? 374 LYS B CE 1 ATOM 6888 N NZ . LYS B 1 374 ? 43.431 42.516 -36.498 1.00 33.06 ? 374 LYS B NZ 1 ATOM 6889 N N . SER B 1 375 ? 48.546 39.265 -34.416 1.00 12.76 ? 375 SER B N 1 ATOM 6890 C CA . SER B 1 375 ? 49.763 39.526 -35.176 1.00 11.62 ? 375 SER B CA 1 ATOM 6891 C C . SER B 1 375 ? 50.671 38.329 -34.941 1.00 11.84 ? 375 SER B C 1 ATOM 6892 O O . SER B 1 375 ? 50.878 37.912 -33.802 1.00 12.62 ? 375 SER B O 1 ATOM 6893 C CB . SER B 1 375 ? 50.463 40.795 -34.691 1.00 12.25 ? 375 SER B CB 1 ATOM 6894 O OG . SER B 1 375 ? 51.721 40.940 -35.331 1.00 11.84 ? 375 SER B OG 1 ATOM 6895 N N . SER B 1 376 ? 51.215 37.774 -36.013 1.00 13.29 ? 376 SER B N 1 ATOM 6896 C CA . SER B 1 376 ? 52.082 36.612 -35.880 1.00 14.27 ? 376 SER B CA 1 ATOM 6897 C C . SER B 1 376 ? 53.507 36.982 -35.493 1.00 13.17 ? 376 SER B C 1 ATOM 6898 O O . SER B 1 376 ? 54.333 36.099 -35.270 1.00 14.31 ? 376 SER B O 1 ATOM 6899 C CB . SER B 1 376 ? 52.101 35.824 -37.192 1.00 16.12 ? 376 SER B CB 1 ATOM 6900 O OG . SER B 1 376 ? 52.638 36.607 -38.244 1.00 17.85 ? 376 SER B OG 1 ATOM 6901 N N . SER B 1 377 ? 53.796 38.276 -35.389 1.00 14.09 ? 377 SER B N 1 ATOM 6902 C CA . SER B 1 377 ? 55.156 38.701 -35.067 1.00 14.56 ? 377 SER B CA 1 ATOM 6903 C C . SER B 1 377 ? 55.312 39.850 -34.076 1.00 15.47 ? 377 SER B C 1 ATOM 6904 O O . SER B 1 377 ? 56.373 40.000 -33.473 1.00 18.26 ? 377 SER B O 1 ATOM 6905 C CB . SER B 1 377 ? 55.884 39.085 -36.356 1.00 16.25 ? 377 SER B CB 1 ATOM 6906 O OG . SER B 1 377 ? 55.278 40.223 -36.951 1.00 16.65 ? 377 SER B OG 1 ATOM 6907 N N . ASN B 1 378 ? 54.271 40.657 -33.906 1.00 13.23 ? 378 ASN B N 1 ATOM 6908 C CA . ASN B 1 378 ? 54.347 41.808 -33.011 1.00 12.55 ? 378 ASN B CA 1 ATOM 6909 C C . ASN B 1 378 ? 53.677 41.556 -31.660 1.00 10.94 ? 378 ASN B C 1 ATOM 6910 O O . ASN B 1 378 ? 52.453 41.498 -31.567 1.00 11.38 ? 378 ASN B O 1 ATOM 6911 C CB . ASN B 1 378 ? 53.699 43.018 -33.688 1.00 13.20 ? 378 ASN B CB 1 ATOM 6912 C CG . ASN B 1 378 ? 54.069 44.329 -33.027 1.00 15.34 ? 378 ASN B CG 1 ATOM 6913 O OD1 . ASN B 1 378 ? 54.454 44.364 -31.858 1.00 15.68 ? 378 ASN B OD1 1 ATOM 6914 N ND2 . ASN B 1 378 ? 53.940 45.424 -33.774 1.00 17.25 ? 378 ASN B ND2 1 ATOM 6915 N N . VAL B 1 379 ? 54.490 41.432 -30.613 1.00 9.86 ? 379 VAL B N 1 ATOM 6916 C CA . VAL B 1 379 ? 53.983 41.181 -29.269 1.00 9.38 ? 379 VAL B CA 1 ATOM 6917 C C . VAL B 1 379 ? 53.228 42.389 -28.696 1.00 10.35 ? 379 VAL B C 1 ATOM 6918 O O . VAL B 1 379 ? 52.515 42.267 -27.700 1.00 10.04 ? 379 VAL B O 1 ATOM 6919 C CB . VAL B 1 379 ? 55.144 40.782 -28.308 1.00 8.91 ? 379 VAL B CB 1 ATOM 6920 C CG1 . VAL B 1 379 ? 56.002 42.002 -27.978 1.00 9.27 ? 379 VAL B CG1 1 ATOM 6921 C CG2 . VAL B 1 379 ? 54.586 40.142 -27.040 1.00 8.30 ? 379 VAL B CG2 1 ATOM 6922 N N . ARG B 1 380 ? 53.384 43.553 -29.323 1.00 11.42 ? 380 ARG B N 1 ATOM 6923 C CA . ARG B 1 380 ? 52.704 44.761 -28.859 1.00 13.27 ? 380 ARG B CA 1 ATOM 6924 C C . ARG B 1 380 ? 51.276 44.868 -29.384 1.00 12.16 ? 380 ARG B C 1 ATOM 6925 O O . ARG B 1 380 ? 50.543 45.790 -29.026 1.00 13.71 ? 380 ARG B O 1 ATOM 6926 C CB . ARG B 1 380 ? 53.478 46.011 -29.269 1.00 15.65 ? 380 ARG B CB 1 ATOM 6927 C CG . ARG B 1 380 ? 54.831 46.182 -28.608 1.00 21.00 ? 380 ARG B CG 1 ATOM 6928 C CD . ARG B 1 380 ? 55.478 47.454 -29.128 1.00 25.39 ? 380 ARG B CD 1 ATOM 6929 N NE . ARG B 1 380 ? 56.812 47.687 -28.588 1.00 30.13 ? 380 ARG B NE 1 ATOM 6930 C CZ . ARG B 1 380 ? 57.064 48.179 -27.380 1.00 32.33 ? 380 ARG B CZ 1 ATOM 6931 N NH1 . ARG B 1 380 ? 56.071 48.499 -26.567 1.00 33.18 ? 380 ARG B NH1 1 ATOM 6932 N NH2 . ARG B 1 380 ? 58.318 48.365 -26.997 1.00 33.55 ? 380 ARG B NH2 1 ATOM 6933 N N . VAL B 1 381 ? 50.889 43.940 -30.252 1.00 11.30 ? 381 VAL B N 1 ATOM 6934 C CA . VAL B 1 381 ? 49.534 43.931 -30.791 1.00 12.10 ? 381 VAL B CA 1 ATOM 6935 C C . VAL B 1 381 ? 48.731 42.971 -29.923 1.00 12.35 ? 381 VAL B C 1 ATOM 6936 O O . VAL B 1 381 ? 49.044 41.783 -29.845 1.00 13.10 ? 381 VAL B O 1 ATOM 6937 C CB . VAL B 1 381 ? 49.504 43.450 -32.260 1.00 11.69 ? 381 VAL B CB 1 ATOM 6938 C CG1 . VAL B 1 381 ? 48.068 43.364 -32.753 1.00 13.41 ? 381 VAL B CG1 1 ATOM 6939 C CG2 . VAL B 1 381 ? 50.290 44.415 -33.134 1.00 12.27 ? 381 VAL B CG2 1 ATOM 6940 N N . SER B 1 382 ? 47.705 43.496 -29.261 1.00 12.40 ? 382 SER B N 1 ATOM 6941 C CA . SER B 1 382 ? 46.867 42.698 -28.372 1.00 13.73 ? 382 SER B CA 1 ATOM 6942 C C . SER B 1 382 ? 46.305 41.453 -29.041 1.00 12.99 ? 382 SER B C 1 ATOM 6943 O O . SER B 1 382 ? 45.884 41.489 -30.192 1.00 13.23 ? 382 SER B O 1 ATOM 6944 C CB . SER B 1 382 ? 45.708 43.544 -27.839 1.00 15.29 ? 382 SER B CB 1 ATOM 6945 O OG A SER B 1 382 ? 46.182 44.660 -27.111 0.50 16.97 ? 382 SER B OG 1 ATOM 6946 O OG B SER B 1 382 ? 44.892 42.832 -26.947 0.50 16.98 ? 382 SER B OG 1 ATOM 6947 N N . PRO B 1 383 ? 46.297 40.324 -28.320 1.00 12.75 ? 383 PRO B N 1 ATOM 6948 C CA . PRO B 1 383 ? 45.767 39.082 -28.891 1.00 12.19 ? 383 PRO B CA 1 ATOM 6949 C C . PRO B 1 383 ? 44.254 39.157 -28.920 1.00 12.27 ? 383 PRO B C 1 ATOM 6950 O O . PRO B 1 383 ? 43.658 40.014 -28.269 1.00 13.88 ? 383 PRO B O 1 ATOM 6951 C CB . PRO B 1 383 ? 46.222 38.010 -27.898 1.00 11.41 ? 383 PRO B CB 1 ATOM 6952 C CG . PRO B 1 383 ? 47.388 38.653 -27.164 1.00 14.04 ? 383 PRO B CG 1 ATOM 6953 C CD . PRO B 1 383 ? 46.928 40.078 -27.012 1.00 12.81 ? 383 PRO B CD 1 ATOM 6954 N N . ASN B 1 384 ? 43.629 38.265 -29.673 1.00 10.61 ? 384 ASN B N 1 ATOM 6955 C CA . ASN B 1 384 ? 42.182 38.228 -29.689 1.00 12.52 ? 384 ASN B CA 1 ATOM 6956 C C . ASN B 1 384 ? 41.813 37.243 -28.597 1.00 11.31 ? 384 ASN B C 1 ATOM 6957 O O . ASN B 1 384 ? 42.498 36.249 -28.409 1.00 11.88 ? 384 ASN B O 1 ATOM 6958 C CB . ASN B 1 384 ? 41.652 37.724 -31.035 1.00 12.87 ? 384 ASN B CB 1 ATOM 6959 C CG . ASN B 1 384 ? 41.662 38.798 -32.110 0.50 15.88 ? 384 ASN B CG 1 ATOM 6960 O OD1 . ASN B 1 384 ? 41.191 39.914 -31.891 0.50 18.40 ? 384 ASN B OD1 1 ATOM 6961 N ND2 . ASN B 1 384 ? 42.182 38.458 -33.283 0.50 17.82 ? 384 ASN B ND2 1 ATOM 6962 N N . VAL B 1 385 ? 40.738 37.522 -27.876 1.00 10.34 ? 385 VAL B N 1 ATOM 6963 C CA . VAL B 1 385 ? 40.288 36.636 -26.824 1.00 9.25 ? 385 VAL B CA 1 ATOM 6964 C C . VAL B 1 385 ? 38.772 36.576 -26.807 1.00 9.87 ? 385 VAL B C 1 ATOM 6965 O O . VAL B 1 385 ? 38.103 37.583 -27.025 1.00 8.92 ? 385 VAL B O 1 ATOM 6966 C CB . VAL B 1 385 ? 40.780 37.110 -25.430 1.00 11.09 ? 385 VAL B CB 1 ATOM 6967 C CG1 . VAL B 1 385 ? 42.292 37.076 -25.359 0.50 7.89 ? 385 VAL B CG1 1 ATOM 6968 C CG2 . VAL B 1 385 ? 40.280 38.519 -25.147 0.50 7.36 ? 385 VAL B CG2 1 ATOM 6969 N N . LYS B 1 386 ? 38.234 35.384 -26.585 1.00 7.97 ? 386 LYS B N 1 ATOM 6970 C CA . LYS B 1 386 ? 36.791 35.208 -26.488 1.00 8.96 ? 386 LYS B CA 1 ATOM 6971 C C . LYS B 1 386 ? 36.516 34.426 -25.212 1.00 9.05 ? 386 LYS B C 1 ATOM 6972 O O . LYS B 1 386 ? 37.196 33.441 -24.930 1.00 9.80 ? 386 LYS B O 1 ATOM 6973 C CB . LYS B 1 386 ? 36.234 34.465 -27.705 1.00 10.45 ? 386 LYS B CB 1 ATOM 6974 C CG . LYS B 1 386 ? 34.711 34.468 -27.728 1.00 11.71 ? 386 LYS B CG 1 ATOM 6975 C CD . LYS B 1 386 ? 34.142 33.899 -29.009 1.00 12.02 ? 386 LYS B CD 1 ATOM 6976 C CE . LYS B 1 386 ? 32.639 34.139 -29.066 1.00 13.95 ? 386 LYS B CE 1 ATOM 6977 N NZ . LYS B 1 386 ? 32.035 33.624 -30.327 1.00 15.16 ? 386 LYS B NZ 1 ATOM 6978 N N . PHE B 1 387 ? 35.526 34.860 -24.437 1.00 7.55 ? 387 PHE B N 1 ATOM 6979 C CA . PHE B 1 387 ? 35.220 34.187 -23.178 1.00 7.25 ? 387 PHE B CA 1 ATOM 6980 C C . PHE B 1 387 ? 33.937 33.350 -23.183 1.00 7.17 ? 387 PHE B C 1 ATOM 6981 O O . PHE B 1 387 ? 33.728 32.523 -22.298 1.00 7.63 ? 387 PHE B O 1 ATOM 6982 C CB . PHE B 1 387 ? 35.172 35.222 -22.050 1.00 8.44 ? 387 PHE B CB 1 ATOM 6983 C CG . PHE B 1 387 ? 36.472 35.962 -21.845 1.00 6.75 ? 387 PHE B CG 1 ATOM 6984 C CD1 . PHE B 1 387 ? 36.543 37.339 -22.034 1.00 6.46 ? 387 PHE B CD1 1 ATOM 6985 C CD2 . PHE B 1 387 ? 37.617 35.285 -21.430 1.00 7.18 ? 387 PHE B CD2 1 ATOM 6986 C CE1 . PHE B 1 387 ? 37.735 38.035 -21.805 1.00 7.94 ? 387 PHE B CE1 1 ATOM 6987 C CE2 . PHE B 1 387 ? 38.814 35.969 -21.198 1.00 7.33 ? 387 PHE B CE2 1 ATOM 6988 C CZ . PHE B 1 387 ? 38.872 37.348 -21.385 1.00 7.57 ? 387 PHE B CZ 1 ATOM 6989 N N . ASN B 1 388 ? 33.089 33.559 -24.185 1.00 6.43 ? 388 ASN B N 1 ATOM 6990 C CA . ASN B 1 388 ? 31.835 32.815 -24.312 1.00 7.22 ? 388 ASN B CA 1 ATOM 6991 C C . ASN B 1 388 ? 30.942 32.889 -23.076 1.00 7.26 ? 388 ASN B C 1 ATOM 6992 O O . ASN B 1 388 ? 30.475 31.867 -22.565 1.00 6.84 ? 388 ASN B O 1 ATOM 6993 C CB . ASN B 1 388 ? 32.128 31.350 -24.655 1.00 7.87 ? 388 ASN B CB 1 ATOM 6994 C CG . ASN B 1 388 ? 32.764 31.193 -26.020 1.00 10.15 ? 388 ASN B CG 1 ATOM 6995 O OD1 . ASN B 1 388 ? 32.283 31.754 -27.005 1.00 10.71 ? 388 ASN B OD1 1 ATOM 6996 N ND2 . ASN B 1 388 ? 33.847 30.426 -26.089 1.00 10.32 ? 388 ASN B ND2 1 ATOM 6997 N N . TYR B 1 389 ? 30.696 34.107 -22.609 1.00 6.95 ? 389 TYR B N 1 ATOM 6998 C CA . TYR B 1 389 ? 29.860 34.321 -21.438 1.00 7.32 ? 389 TYR B CA 1 ATOM 6999 C C . TYR B 1 389 ? 28.548 33.560 -21.543 1.00 8.14 ? 389 TYR B C 1 ATOM 7000 O O . TYR B 1 389 ? 27.871 33.592 -22.577 1.00 8.39 ? 389 TYR B O 1 ATOM 7001 C CB . TYR B 1 389 ? 29.550 35.810 -21.254 1.00 7.77 ? 389 TYR B CB 1 ATOM 7002 C CG . TYR B 1 389 ? 30.763 36.695 -21.105 1.00 7.43 ? 389 TYR B CG 1 ATOM 7003 C CD1 . TYR B 1 389 ? 31.287 37.385 -22.199 1.00 7.62 ? 389 TYR B CD1 1 ATOM 7004 C CD2 . TYR B 1 389 ? 31.387 36.848 -19.866 1.00 7.38 ? 389 TYR B CD2 1 ATOM 7005 C CE1 . TYR B 1 389 ? 32.404 38.207 -22.066 1.00 6.75 ? 389 TYR B CE1 1 ATOM 7006 C CE2 . TYR B 1 389 ? 32.507 37.666 -19.718 1.00 7.35 ? 389 TYR B CE2 1 ATOM 7007 C CZ . TYR B 1 389 ? 33.008 38.343 -20.822 1.00 7.01 ? 389 TYR B CZ 1 ATOM 7008 O OH . TYR B 1 389 ? 34.106 39.157 -20.683 1.00 8.51 ? 389 TYR B OH 1 ATOM 7009 N N . TYR B 1 390 ? 28.209 32.866 -20.462 1.00 7.67 ? 390 TYR B N 1 ATOM 7010 C CA . TYR B 1 390 ? 26.971 32.104 -20.356 1.00 8.14 ? 390 TYR B CA 1 ATOM 7011 C C . TYR B 1 390 ? 26.759 30.961 -21.345 1.00 9.61 ? 390 TYR B C 1 ATOM 7012 O O . TYR B 1 390 ? 25.633 30.495 -21.530 1.00 11.26 ? 390 TYR B O 1 ATOM 7013 C CB . TYR B 1 390 ? 25.781 33.077 -20.373 1.00 8.16 ? 390 TYR B CB 1 ATOM 7014 C CG . TYR B 1 390 ? 25.809 34.012 -19.179 1.00 10.45 ? 390 TYR B CG 1 ATOM 7015 C CD1 . TYR B 1 390 ? 25.707 35.398 -19.336 1.00 11.50 ? 390 TYR B CD1 1 ATOM 7016 C CD2 . TYR B 1 390 ? 26.007 33.510 -17.893 1.00 10.65 ? 390 TYR B CD2 1 ATOM 7017 C CE1 . TYR B 1 390 ? 25.815 36.257 -18.232 1.00 13.24 ? 390 TYR B CE1 1 ATOM 7018 C CE2 . TYR B 1 390 ? 26.116 34.358 -16.792 1.00 11.35 ? 390 TYR B CE2 1 ATOM 7019 C CZ . TYR B 1 390 ? 26.024 35.723 -16.966 1.00 11.78 ? 390 TYR B CZ 1 ATOM 7020 O OH . TYR B 1 390 ? 26.186 36.549 -15.873 1.00 11.93 ? 390 TYR B OH 1 ATOM 7021 N N . SER B 1 391 ? 27.836 30.494 -21.971 1.00 8.98 ? 391 SER B N 1 ATOM 7022 C CA . SER B 1 391 ? 27.722 29.368 -22.893 1.00 10.13 ? 391 SER B CA 1 ATOM 7023 C C . SER B 1 391 ? 27.367 28.150 -22.042 1.00 10.86 ? 391 SER B C 1 ATOM 7024 O O . SER B 1 391 ? 26.699 27.221 -22.501 1.00 12.80 ? 391 SER B O 1 ATOM 7025 C CB . SER B 1 391 ? 29.036 29.150 -23.649 1.00 9.78 ? 391 SER B CB 1 ATOM 7026 O OG . SER B 1 391 ? 30.131 29.020 -22.761 1.00 12.89 ? 391 SER B OG 1 ATOM 7027 N N . ASN B 1 392 ? 27.822 28.158 -20.792 1.00 11.14 ? 392 ASN B N 1 ATOM 7028 C CA . ASN B 1 392 ? 27.492 27.086 -19.868 1.00 11.16 ? 392 ASN B CA 1 ATOM 7029 C C . ASN B 1 392 ? 26.289 27.610 -19.092 1.00 11.66 ? 392 ASN B C 1 ATOM 7030 O O . ASN B 1 392 ? 26.382 28.619 -18.388 1.00 10.60 ? 392 ASN B O 1 ATOM 7031 C CB . ASN B 1 392 ? 28.643 26.800 -18.910 1.00 11.80 ? 392 ASN B CB 1 ATOM 7032 C CG . ASN B 1 392 ? 28.374 25.592 -18.048 1.00 12.50 ? 392 ASN B CG 1 ATOM 7033 O OD1 . ASN B 1 392 ? 27.496 25.617 -17.188 1.00 13.27 ? 392 ASN B OD1 1 ATOM 7034 N ND2 . ASN B 1 392 ? 29.116 24.519 -18.293 1.00 15.37 ? 392 ASN B ND2 1 ATOM 7035 N N . LEU B 1 393 ? 25.157 26.928 -19.226 1.00 10.90 ? 393 LEU B N 1 ATOM 7036 C CA . LEU B 1 393 ? 23.931 27.367 -18.574 1.00 9.80 ? 393 LEU B CA 1 ATOM 7037 C C . LEU B 1 393 ? 23.954 27.407 -17.053 1.00 8.87 ? 393 LEU B C 1 ATOM 7038 O O . LEU B 1 393 ? 23.141 28.103 -16.443 1.00 9.69 ? 393 LEU B O 1 ATOM 7039 C CB . LEU B 1 393 ? 22.753 26.520 -19.063 1.00 11.76 ? 393 LEU B CB 1 ATOM 7040 C CG . LEU B 1 393 ? 22.497 26.641 -20.570 1.00 14.30 ? 393 LEU B CG 1 ATOM 7041 C CD1 . LEU B 1 393 ? 21.344 25.735 -20.959 1.00 15.29 ? 393 LEU B CD1 1 ATOM 7042 C CD2 . LEU B 1 393 ? 22.186 28.088 -20.936 1.00 15.34 ? 393 LEU B CD2 1 ATOM 7043 N N . THR B 1 394 ? 24.870 26.674 -16.429 1.00 8.13 ? 394 THR B N 1 ATOM 7044 C CA . THR B 1 394 ? 24.946 26.707 -14.973 1.00 8.68 ? 394 THR B CA 1 ATOM 7045 C C . THR B 1 394 ? 25.446 28.094 -14.555 1.00 9.08 ? 394 THR B C 1 ATOM 7046 O O . THR B 1 394 ? 25.035 28.618 -13.520 1.00 9.50 ? 394 THR B O 1 ATOM 7047 C CB . THR B 1 394 ? 25.859 25.587 -14.423 1.00 9.74 ? 394 THR B CB 1 ATOM 7048 O OG1 . THR B 1 394 ? 25.254 24.313 -14.692 1.00 12.27 ? 394 THR B OG1 1 ATOM 7049 C CG2 . THR B 1 394 ? 26.042 25.732 -12.918 1.00 10.55 ? 394 THR B CG2 1 ATOM 7050 N N . ASP B 1 395 ? 26.314 28.701 -15.363 1.00 7.77 ? 395 ASP B N 1 ATOM 7051 C CA . ASP B 1 395 ? 26.785 30.051 -15.049 1.00 8.28 ? 395 ASP B CA 1 ATOM 7052 C C . ASP B 1 395 ? 25.572 30.989 -15.077 1.00 7.74 ? 395 ASP B C 1 ATOM 7053 O O . ASP B 1 395 ? 25.438 31.873 -14.228 1.00 7.48 ? 395 ASP B O 1 ATOM 7054 C CB . ASP B 1 395 ? 27.806 30.562 -16.079 1.00 7.46 ? 395 ASP B CB 1 ATOM 7055 C CG . ASP B 1 395 ? 29.195 29.956 -15.911 1.00 8.19 ? 395 ASP B CG 1 ATOM 7056 O OD1 . ASP B 1 395 ? 29.492 29.370 -14.847 1.00 7.49 ? 395 ASP B OD1 1 ATOM 7057 O OD2 . ASP B 1 395 ? 30.002 30.091 -16.855 1.00 8.74 ? 395 ASP B OD2 1 ATOM 7058 N N . LEU B 1 396 ? 24.696 30.801 -16.066 1.00 7.99 ? 396 LEU B N 1 ATOM 7059 C CA . LEU B 1 396 ? 23.504 31.638 -16.207 1.00 7.41 ? 396 LEU B CA 1 ATOM 7060 C C . LEU B 1 396 ? 22.569 31.494 -15.008 1.00 7.99 ? 396 LEU B C 1 ATOM 7061 O O . LEU B 1 396 ? 22.067 32.486 -14.488 1.00 7.37 ? 396 LEU B O 1 ATOM 7062 C CB . LEU B 1 396 ? 22.753 31.291 -17.504 1.00 8.28 ? 396 LEU B CB 1 ATOM 7063 C CG . LEU B 1 396 ? 21.536 32.163 -17.845 1.00 7.26 ? 396 LEU B CG 1 ATOM 7064 C CD1 . LEU B 1 396 ? 21.947 33.625 -17.951 1.00 8.99 ? 396 LEU B CD1 1 ATOM 7065 C CD2 . LEU B 1 396 ? 20.920 31.688 -19.157 1.00 9.26 ? 396 LEU B CD2 1 ATOM 7066 N N . SER B 1 397 ? 22.337 30.262 -14.568 1.00 8.81 ? 397 SER B N 1 ATOM 7067 C CA . SER B 1 397 ? 21.470 30.036 -13.416 1.00 8.29 ? 397 SER B CA 1 ATOM 7068 C C . SER B 1 397 ? 22.040 30.771 -12.208 1.00 9.30 ? 397 SER B C 1 ATOM 7069 O O . SER B 1 397 ? 21.301 31.345 -11.406 1.00 9.17 ? 397 SER B O 1 ATOM 7070 C CB . SER B 1 397 ? 21.365 28.538 -13.110 1.00 9.92 ? 397 SER B CB 1 ATOM 7071 O OG A SER B 1 397 ? 22.617 28.001 -12.734 0.50 13.48 ? 397 SER B OG 1 ATOM 7072 O OG B SER B 1 397 ? 20.500 28.337 -11.996 0.50 13.31 ? 397 SER B OG 1 ATOM 7073 N N . HIS B 1 398 ? 23.362 30.753 -12.085 1.00 8.78 ? 398 HIS B N 1 ATOM 7074 C CA . HIS B 1 398 ? 24.023 31.429 -10.979 1.00 8.50 ? 398 HIS B CA 1 ATOM 7075 C C . HIS B 1 398 ? 23.872 32.942 -11.087 1.00 9.84 ? 398 HIS B C 1 ATOM 7076 O O . HIS B 1 398 ? 23.746 33.618 -10.068 1.00 9.78 ? 398 HIS B O 1 ATOM 7077 C CB . HIS B 1 398 ? 25.495 31.018 -10.918 1.00 9.76 ? 398 HIS B CB 1 ATOM 7078 C CG . HIS B 1 398 ? 25.694 29.595 -10.498 1.00 11.18 ? 398 HIS B CG 1 ATOM 7079 N ND1 . HIS B 1 398 ? 26.900 28.939 -10.623 1.00 10.87 ? 398 HIS B ND1 1 ATOM 7080 C CD2 . HIS B 1 398 ? 24.836 28.701 -9.951 1.00 11.09 ? 398 HIS B CD2 1 ATOM 7081 C CE1 . HIS B 1 398 ? 26.775 27.704 -10.172 1.00 11.42 ? 398 HIS B CE1 1 ATOM 7082 N NE2 . HIS B 1 398 ? 25.532 27.533 -9.759 1.00 12.09 ? 398 HIS B NE2 1 ATOM 7083 N N . CYS B 1 399 ? 23.871 33.475 -12.310 1.00 9.33 ? 399 CYS B N 1 ATOM 7084 C CA . CYS B 1 399 ? 23.692 34.917 -12.496 1.00 8.79 ? 399 CYS B CA 1 ATOM 7085 C C . CYS B 1 399 ? 22.298 35.289 -12.029 1.00 8.55 ? 399 CYS B C 1 ATOM 7086 O O . CYS B 1 399 ? 22.099 36.297 -11.355 1.00 8.75 ? 399 CYS B O 1 ATOM 7087 C CB . CYS B 1 399 ? 23.823 35.337 -13.968 1.00 10.46 ? 399 CYS B CB 1 ATOM 7088 S SG . CYS B 1 399 ? 23.429 37.112 -14.202 1.00 14.49 ? 399 CYS B SG 1 ATOM 7089 N N . VAL B 1 400 ? 21.328 34.473 -12.413 1.00 9.25 ? 400 VAL B N 1 ATOM 7090 C CA . VAL B 1 400 ? 19.941 34.708 -12.040 1.00 9.12 ? 400 VAL B CA 1 ATOM 7091 C C . VAL B 1 400 ? 19.789 34.763 -10.525 1.00 9.60 ? 400 VAL B C 1 ATOM 7092 O O . VAL B 1 400 ? 19.196 35.697 -9.988 1.00 8.48 ? 400 VAL B O 1 ATOM 7093 C CB . VAL B 1 400 ? 19.011 33.611 -12.614 1.00 8.96 ? 400 VAL B CB 1 ATOM 7094 C CG1 . VAL B 1 400 ? 17.594 33.802 -12.093 1.00 9.83 ? 400 VAL B CG1 1 ATOM 7095 C CG2 . VAL B 1 400 ? 19.018 33.682 -14.138 1.00 10.21 ? 400 VAL B CG2 1 ATOM 7096 N N . SER B 1 401 ? 20.331 33.765 -9.834 1.00 9.66 ? 401 SER B N 1 ATOM 7097 C CA . SER B 1 401 ? 20.250 33.733 -8.379 1.00 9.17 ? 401 SER B CA 1 ATOM 7098 C C . SER B 1 401 ? 20.942 34.959 -7.797 1.00 8.88 ? 401 SER B C 1 ATOM 7099 O O . SER B 1 401 ? 20.443 35.585 -6.861 1.00 8.31 ? 401 SER B O 1 ATOM 7100 C CB . SER B 1 401 ? 20.905 32.460 -7.840 1.00 11.03 ? 401 SER B CB 1 ATOM 7101 O OG . SER B 1 401 ? 20.225 31.308 -8.308 1.00 15.51 ? 401 SER B OG 1 ATOM 7102 N N . GLY B 1 402 ? 22.093 35.301 -8.366 1.00 7.78 ? 402 GLY B N 1 ATOM 7103 C CA . GLY B 1 402 ? 22.834 36.456 -7.897 1.00 7.08 ? 402 GLY B CA 1 ATOM 7104 C C . GLY B 1 402 ? 22.072 37.758 -8.055 1.00 7.19 ? 402 GLY B C 1 ATOM 7105 O O . GLY B 1 402 ? 22.047 38.571 -7.136 1.00 7.19 ? 402 GLY B O 1 ATOM 7106 N N . MET B 1 403 ? 21.443 37.969 -9.208 1.00 6.69 ? 403 MET B N 1 ATOM 7107 C CA . MET B 1 403 ? 20.700 39.208 -9.409 1.00 7.09 ? 403 MET B CA 1 ATOM 7108 C C . MET B 1 403 ? 19.424 39.268 -8.576 1.00 7.90 ? 403 MET B C 1 ATOM 7109 O O . MET B 1 403 ? 18.955 40.349 -8.231 1.00 7.54 ? 403 MET B O 1 ATOM 7110 C CB . MET B 1 403 ? 20.406 39.429 -10.895 1.00 7.99 ? 403 MET B CB 1 ATOM 7111 C CG . MET B 1 403 ? 21.663 39.705 -11.724 1.00 7.48 ? 403 MET B CG 1 ATOM 7112 S SD . MET B 1 403 ? 22.884 40.805 -10.922 1.00 10.30 ? 403 MET B SD 1 ATOM 7113 C CE . MET B 1 403 ? 21.993 42.387 -10.883 1.00 10.53 ? 403 MET B CE 1 ATOM 7114 N N . LYS B 1 404 ? 18.860 38.111 -8.252 1.00 8.38 ? 404 LYS B N 1 ATOM 7115 C CA . LYS B 1 404 ? 17.681 38.088 -7.402 1.00 9.26 ? 404 LYS B CA 1 ATOM 7116 C C . LYS B 1 404 ? 18.120 38.542 -6.018 1.00 9.42 ? 404 LYS B C 1 ATOM 7117 O O . LYS B 1 404 ? 17.376 39.225 -5.317 1.00 9.08 ? 404 LYS B O 1 ATOM 7118 C CB . LYS B 1 404 ? 17.081 36.678 -7.324 1.00 9.96 ? 404 LYS B CB 1 ATOM 7119 C CG . LYS B 1 404 ? 16.274 36.257 -8.542 1.00 9.93 ? 404 LYS B CG 1 ATOM 7120 C CD . LYS B 1 404 ? 15.763 34.836 -8.368 1.00 9.22 ? 404 LYS B CD 1 ATOM 7121 C CE . LYS B 1 404 ? 14.857 34.418 -9.509 1.00 9.94 ? 404 LYS B CE 1 ATOM 7122 N NZ . LYS B 1 404 ? 14.438 32.995 -9.375 1.00 11.21 ? 404 LYS B NZ 1 ATOM 7123 N N . LYS B 1 405 ? 19.337 38.172 -5.623 1.00 8.87 ? 405 LYS B N 1 ATOM 7124 C CA . LYS B 1 405 ? 19.838 38.580 -4.314 1.00 7.96 ? 405 LYS B CA 1 ATOM 7125 C C . LYS B 1 405 ? 20.038 40.095 -4.308 1.00 8.33 ? 405 LYS B C 1 ATOM 7126 O O . LYS B 1 405 ? 19.777 40.761 -3.307 1.00 8.01 ? 405 LYS B O 1 ATOM 7127 C CB . LYS B 1 405 ? 21.146 37.853 -3.970 1.00 8.31 ? 405 LYS B CB 1 ATOM 7128 C CG . LYS B 1 405 ? 21.712 38.214 -2.585 1.00 6.86 ? 405 LYS B CG 1 ATOM 7129 C CD . LYS B 1 405 ? 20.745 37.873 -1.445 1.00 8.42 ? 405 LYS B CD 1 ATOM 7130 C CE . LYS B 1 405 ? 20.568 36.370 -1.278 1.00 8.98 ? 405 LYS B CE 1 ATOM 7131 N NZ . LYS B 1 405 ? 19.628 36.031 -0.159 1.00 11.21 ? 405 LYS B NZ 1 ATOM 7132 N N . ILE B 1 406 ? 20.492 40.645 -5.431 1.00 8.07 ? 406 ILE B N 1 ATOM 7133 C CA . ILE B 1 406 ? 20.656 42.091 -5.528 1.00 8.99 ? 406 ILE B CA 1 ATOM 7134 C C . ILE B 1 406 ? 19.252 42.676 -5.368 1.00 8.75 ? 406 ILE B C 1 ATOM 7135 O O . ILE B 1 406 ? 19.062 43.698 -4.706 1.00 8.72 ? 406 ILE B O 1 ATOM 7136 C CB . ILE B 1 406 ? 21.248 42.524 -6.898 1.00 8.41 ? 406 ILE B CB 1 ATOM 7137 C CG1 . ILE B 1 406 ? 22.694 42.029 -7.026 1.00 8.78 ? 406 ILE B CG1 1 ATOM 7138 C CG2 . ILE B 1 406 ? 21.190 44.040 -7.035 1.00 9.40 ? 406 ILE B CG2 1 ATOM 7139 C CD1 . ILE B 1 406 ? 23.627 42.519 -5.925 1.00 11.75 ? 406 ILE B CD1 1 ATOM 7140 N N . GLY B 1 407 ? 18.264 42.009 -5.963 1.00 9.81 ? 407 GLY B N 1 ATOM 7141 C CA . GLY B 1 407 ? 16.888 42.463 -5.844 1.00 8.93 ? 407 GLY B CA 1 ATOM 7142 C C . GLY B 1 407 ? 16.484 42.521 -4.382 1.00 9.54 ? 407 GLY B C 1 ATOM 7143 O O . GLY B 1 407 ? 15.779 43.437 -3.954 1.00 10.37 ? 407 GLY B O 1 ATOM 7144 N N . GLU B 1 408 ? 16.927 41.537 -3.606 1.00 9.09 ? 408 GLU B N 1 ATOM 7145 C CA . GLU B 1 408 ? 16.621 41.509 -2.180 1.00 9.03 ? 408 GLU B CA 1 ATOM 7146 C C . GLU B 1 408 ? 17.269 42.710 -1.497 1.00 9.42 ? 408 GLU B C 1 ATOM 7147 O O . GLU B 1 408 ? 16.643 43.368 -0.666 1.00 10.41 ? 408 GLU B O 1 ATOM 7148 C CB . GLU B 1 408 ? 17.134 40.219 -1.535 1.00 8.61 ? 408 GLU B CB 1 ATOM 7149 C CG . GLU B 1 408 ? 16.276 38.992 -1.802 1.00 11.19 ? 408 GLU B CG 1 ATOM 7150 C CD . GLU B 1 408 ? 16.707 37.801 -0.961 1.00 12.85 ? 408 GLU B CD 1 ATOM 7151 O OE1 . GLU B 1 408 ? 17.434 36.925 -1.475 1.00 14.08 ? 408 GLU B OE1 1 ATOM 7152 O OE2 . GLU B 1 408 ? 16.327 37.754 0.228 1.00 16.94 ? 408 GLU B OE2 1 ATOM 7153 N N . LEU B 1 409 ? 18.526 42.988 -1.845 1.00 9.17 ? 409 LEU B N 1 ATOM 7154 C CA . LEU B 1 409 ? 19.229 44.124 -1.260 1.00 9.12 ? 409 LEU B CA 1 ATOM 7155 C C . LEU B 1 409 ? 18.475 45.421 -1.514 1.00 9.71 ? 409 LEU B C 1 ATOM 7156 O O . LEU B 1 409 ? 18.344 46.253 -0.620 1.00 9.87 ? 409 LEU B O 1 ATOM 7157 C CB . LEU B 1 409 ? 20.645 44.248 -1.826 1.00 9.79 ? 409 LEU B CB 1 ATOM 7158 C CG A LEU B 1 409 ? 21.757 43.573 -1.019 0.50 8.45 ? 409 LEU B CG 1 ATOM 7159 C CG B LEU B 1 409 ? 21.574 43.039 -1.564 0.50 8.53 ? 409 LEU B CG 1 ATOM 7160 C CD1 A LEU B 1 409 ? 21.650 42.069 -1.144 0.50 9.46 ? 409 LEU B CD1 1 ATOM 7161 C CD1 B LEU B 1 409 ? 22.946 43.283 -2.174 0.50 9.56 ? 409 LEU B CD1 1 ATOM 7162 C CD2 A LEU B 1 409 ? 23.111 44.049 -1.525 0.50 9.87 ? 409 LEU B CD2 1 ATOM 7163 C CD2 B LEU B 1 409 ? 21.695 42.757 -0.074 0.50 10.04 ? 409 LEU B CD2 1 ATOM 7164 N N . LEU B 1 410 ? 17.986 45.589 -2.739 1.00 10.66 ? 410 LEU B N 1 ATOM 7165 C CA . LEU B 1 410 ? 17.248 46.790 -3.110 1.00 10.76 ? 410 LEU B CA 1 ATOM 7166 C C . LEU B 1 410 ? 15.925 46.915 -2.362 1.00 11.82 ? 410 LEU B C 1 ATOM 7167 O O . LEU B 1 410 ? 15.359 48.006 -2.269 1.00 13.75 ? 410 LEU B O 1 ATOM 7168 C CB . LEU B 1 410 ? 16.976 46.797 -4.615 1.00 10.83 ? 410 LEU B CB 1 ATOM 7169 C CG . LEU B 1 410 ? 18.208 46.942 -5.506 1.00 9.93 ? 410 LEU B CG 1 ATOM 7170 C CD1 . LEU B 1 410 ? 17.790 46.867 -6.970 1.00 13.06 ? 410 LEU B CD1 1 ATOM 7171 C CD2 . LEU B 1 410 ? 18.903 48.261 -5.212 1.00 12.63 ? 410 LEU B CD2 1 ATOM 7172 N N . SER B 1 411 ? 15.442 45.798 -1.828 1.00 10.31 ? 411 SER B N 1 ATOM 7173 C CA . SER B 1 411 ? 14.173 45.773 -1.104 1.00 10.54 ? 411 SER B CA 1 ATOM 7174 C C . SER B 1 411 ? 14.318 45.867 0.414 1.00 11.34 ? 411 SER B C 1 ATOM 7175 O O . SER B 1 411 ? 13.319 45.845 1.137 1.00 12.21 ? 411 SER B O 1 ATOM 7176 C CB . SER B 1 411 ? 13.411 44.494 -1.452 1.00 11.32 ? 411 SER B CB 1 ATOM 7177 O OG . SER B 1 411 ? 13.300 44.334 -2.858 1.00 13.16 ? 411 SER B OG 1 ATOM 7178 N N . THR B 1 412 ? 15.553 45.976 0.895 1.00 11.09 ? 412 THR B N 1 ATOM 7179 C CA . THR B 1 412 ? 15.812 46.051 2.331 1.00 10.38 ? 412 THR B CA 1 ATOM 7180 C C . THR B 1 412 ? 15.478 47.405 2.946 1.00 11.07 ? 412 THR B C 1 ATOM 7181 O O . THR B 1 412 ? 15.427 48.419 2.252 1.00 11.92 ? 412 THR B O 1 ATOM 7182 C CB . THR B 1 412 ? 17.300 45.778 2.662 1.00 8.78 ? 412 THR B CB 1 ATOM 7183 O OG1 . THR B 1 412 ? 18.120 46.763 2.019 1.00 9.94 ? 412 THR B OG1 1 ATOM 7184 C CG2 . THR B 1 412 ? 17.714 44.387 2.206 1.00 8.88 ? 412 THR B CG2 1 ATOM 7185 N N . ASP B 1 413 ? 15.255 47.411 4.258 1.00 12.28 ? 413 ASP B N 1 ATOM 7186 C CA . ASP B 1 413 ? 14.978 48.657 4.967 1.00 12.48 ? 413 ASP B CA 1 ATOM 7187 C C . ASP B 1 413 ? 16.223 49.520 4.791 1.00 12.38 ? 413 ASP B C 1 ATOM 7188 O O . ASP B 1 413 ? 16.142 50.741 4.651 1.00 12.69 ? 413 ASP B O 1 ATOM 7189 C CB . ASP B 1 413 ? 14.782 48.415 6.471 1.00 12.56 ? 413 ASP B CB 1 ATOM 7190 C CG . ASP B 1 413 ? 13.517 47.641 6.797 1.00 14.34 ? 413 ASP B CG 1 ATOM 7191 O OD1 . ASP B 1 413 ? 12.687 47.409 5.894 1.00 14.89 ? 413 ASP B OD1 1 ATOM 7192 O OD2 . ASP B 1 413 ? 13.352 47.272 7.984 1.00 14.49 ? 413 ASP B OD2 1 ATOM 7193 N N . ALA B 1 414 ? 17.378 48.860 4.807 1.00 11.51 ? 414 ALA B N 1 ATOM 7194 C CA . ALA B 1 414 ? 18.668 49.527 4.678 1.00 11.34 ? 414 ALA B CA 1 ATOM 7195 C C . ALA B 1 414 ? 18.803 50.440 3.464 1.00 11.91 ? 414 ALA B C 1 ATOM 7196 O O . ALA B 1 414 ? 19.390 51.510 3.557 1.00 12.70 ? 414 ALA B O 1 ATOM 7197 C CB . ALA B 1 414 ? 19.789 48.488 4.669 1.00 10.95 ? 414 ALA B CB 1 ATOM 7198 N N . LEU B 1 415 ? 18.260 50.039 2.322 1.00 12.07 ? 415 LEU B N 1 ATOM 7199 C CA . LEU B 1 415 ? 18.394 50.878 1.137 1.00 13.54 ? 415 LEU B CA 1 ATOM 7200 C C . LEU B 1 415 ? 17.173 51.755 0.852 1.00 14.81 ? 415 LEU B C 1 ATOM 7201 O O . LEU B 1 415 ? 17.174 52.552 -0.082 1.00 13.33 ? 415 LEU B O 1 ATOM 7202 C CB . LEU B 1 415 ? 18.712 50.007 -0.081 1.00 14.83 ? 415 LEU B CB 1 ATOM 7203 C CG . LEU B 1 415 ? 19.957 49.113 0.004 1.00 16.84 ? 415 LEU B CG 1 ATOM 7204 C CD1 . LEU B 1 415 ? 20.286 48.579 -1.376 1.00 17.69 ? 415 LEU B CD1 1 ATOM 7205 C CD2 . LEU B 1 415 ? 21.134 49.896 0.548 1.00 18.04 ? 415 LEU B CD2 1 ATOM 7206 N N . LYS B 1 416 ? 16.129 51.620 1.660 1.00 15.07 ? 416 LYS B N 1 ATOM 7207 C CA . LYS B 1 416 ? 14.919 52.418 1.463 1.00 16.89 ? 416 LYS B CA 1 ATOM 7208 C C . LYS B 1 416 ? 15.204 53.926 1.363 1.00 16.72 ? 416 LYS B C 1 ATOM 7209 O O . LYS B 1 416 ? 14.630 54.619 0.517 1.00 15.77 ? 416 LYS B O 1 ATOM 7210 C CB . LYS B 1 416 ? 13.922 52.135 2.602 1.00 18.94 ? 416 LYS B CB 1 ATOM 7211 C CG . LYS B 1 416 ? 12.472 52.465 2.277 1.00 23.75 ? 416 LYS B CG 1 ATOM 7212 C CD . LYS B 1 416 ? 11.547 52.102 3.441 1.00 26.51 ? 416 LYS B CD 1 ATOM 7213 C CE . LYS B 1 416 ? 11.426 50.591 3.636 1.00 28.05 ? 416 LYS B CE 1 ATOM 7214 N NZ . LYS B 1 416 ? 10.476 49.949 2.677 1.00 31.05 ? 416 LYS B NZ 1 ATOM 7215 N N . PRO B 1 417 ? 16.090 54.458 2.225 1.00 16.38 ? 417 PRO B N 1 ATOM 7216 C CA . PRO B 1 417 ? 16.416 55.889 2.194 1.00 16.64 ? 417 PRO B CA 1 ATOM 7217 C C . PRO B 1 417 ? 17.074 56.364 0.901 1.00 16.15 ? 417 PRO B C 1 ATOM 7218 O O . PRO B 1 417 ? 17.156 57.565 0.645 1.00 16.02 ? 417 PRO B O 1 ATOM 7219 C CB . PRO B 1 417 ? 17.354 56.059 3.389 1.00 17.24 ? 417 PRO B CB 1 ATOM 7220 C CG . PRO B 1 417 ? 16.920 54.986 4.325 1.00 17.89 ? 417 PRO B CG 1 ATOM 7221 C CD . PRO B 1 417 ? 16.704 53.812 3.398 1.00 16.58 ? 417 PRO B CD 1 ATOM 7222 N N . TYR B 1 418 ? 17.545 55.429 0.085 1.00 15.03 ? 418 TYR B N 1 ATOM 7223 C CA . TYR B 1 418 ? 18.213 55.811 -1.148 1.00 14.58 ? 418 TYR B CA 1 ATOM 7224 C C . TYR B 1 418 ? 17.341 55.751 -2.391 1.00 16.31 ? 418 TYR B C 1 ATOM 7225 O O . TYR B 1 418 ? 17.824 55.922 -3.510 1.00 15.89 ? 418 TYR B O 1 ATOM 7226 C CB . TYR B 1 418 ? 19.489 54.984 -1.305 1.00 15.22 ? 418 TYR B CB 1 ATOM 7227 C CG . TYR B 1 418 ? 20.383 55.167 -0.101 1.00 13.59 ? 418 TYR B CG 1 ATOM 7228 C CD1 . TYR B 1 418 ? 20.340 54.273 0.970 1.00 14.42 ? 418 TYR B CD1 1 ATOM 7229 C CD2 . TYR B 1 418 ? 21.185 56.302 0.023 1.00 12.95 ? 418 TYR B CD2 1 ATOM 7230 C CE1 . TYR B 1 418 ? 21.066 54.512 2.138 1.00 14.96 ? 418 TYR B CE1 1 ATOM 7231 C CE2 . TYR B 1 418 ? 21.910 56.550 1.183 1.00 15.92 ? 418 TYR B CE2 1 ATOM 7232 C CZ . TYR B 1 418 ? 21.845 55.655 2.236 1.00 15.61 ? 418 TYR B CZ 1 ATOM 7233 O OH . TYR B 1 418 ? 22.541 55.918 3.394 1.00 17.22 ? 418 TYR B OH 1 ATOM 7234 N N . LYS B 1 419 ? 16.050 55.514 -2.185 1.00 16.78 ? 419 LYS B N 1 ATOM 7235 C CA . LYS B 1 419 ? 15.091 55.494 -3.281 1.00 18.31 ? 419 LYS B CA 1 ATOM 7236 C C . LYS B 1 419 ? 14.662 56.947 -3.481 1.00 19.43 ? 419 LYS B C 1 ATOM 7237 O O . LYS B 1 419 ? 14.788 57.763 -2.566 1.00 20.45 ? 419 LYS B O 1 ATOM 7238 C CB . LYS B 1 419 ? 13.858 54.660 -2.918 1.00 18.78 ? 419 LYS B CB 1 ATOM 7239 C CG . LYS B 1 419 ? 14.081 53.162 -2.875 1.00 19.29 ? 419 LYS B CG 1 ATOM 7240 C CD . LYS B 1 419 ? 12.752 52.427 -2.774 1.00 19.23 ? 419 LYS B CD 1 ATOM 7241 C CE . LYS B 1 419 ? 12.941 50.920 -2.826 1.00 20.96 ? 419 LYS B CE 1 ATOM 7242 N NZ . LYS B 1 419 ? 11.643 50.194 -2.803 1.00 18.81 ? 419 LYS B NZ 1 ATOM 7243 N N . VAL B 1 420 ? 14.166 57.273 -4.669 1.00 19.99 ? 420 VAL B N 1 ATOM 7244 C CA . VAL B 1 420 ? 13.707 58.630 -4.940 1.00 22.83 ? 420 VAL B CA 1 ATOM 7245 C C . VAL B 1 420 ? 12.197 58.675 -4.751 1.00 25.66 ? 420 VAL B C 1 ATOM 7246 O O . VAL B 1 420 ? 11.598 59.745 -4.713 1.00 26.48 ? 420 VAL B O 1 ATOM 7247 C CB . VAL B 1 420 ? 14.043 59.068 -6.381 1.00 21.70 ? 420 VAL B CB 1 ATOM 7248 C CG1 . VAL B 1 420 ? 15.544 59.121 -6.560 1.00 21.41 ? 420 VAL B CG1 1 ATOM 7249 C CG2 . VAL B 1 420 ? 13.412 58.109 -7.384 1.00 21.92 ? 420 VAL B CG2 1 ATOM 7250 N N . GLU B 1 421 ? 11.596 57.498 -4.621 1.00 28.42 ? 421 GLU B N 1 ATOM 7251 C CA . GLU B 1 421 ? 10.157 57.388 -4.438 1.00 32.66 ? 421 GLU B CA 1 ATOM 7252 C C . GLU B 1 421 ? 9.747 56.128 -3.693 1.00 34.47 ? 421 GLU B C 1 ATOM 7253 O O . GLU B 1 421 ? 10.361 55.080 -3.842 1.00 33.84 ? 421 GLU B O 1 ATOM 7254 C CB . GLU B 1 421 ? 9.454 57.432 -5.807 1.00 33.69 ? 421 GLU B CB 1 ATOM 7255 C CG . GLU B 1 421 ? 8.000 56.959 -5.793 1.00 37.65 ? 421 GLU B CG 1 ATOM 7256 C CD . GLU B 1 421 ? 7.245 57.334 -7.062 1.00 39.47 ? 421 GLU B CD 1 ATOM 7257 O OE1 . GLU B 1 421 ? 7.839 57.270 -8.163 1.00 40.94 ? 421 GLU B OE1 1 ATOM 7258 O OE2 . GLU B 1 421 ? 6.050 57.692 -6.956 1.00 39.69 ? 421 GLU B OE2 1 ATOM 7259 N N . ASP B 1 422 ? 8.688 56.250 -2.899 1.00 37.05 ? 422 ASP B N 1 ATOM 7260 C CA . ASP B 1 422 ? 8.147 55.144 -2.118 1.00 38.52 ? 422 ASP B CA 1 ATOM 7261 C C . ASP B 1 422 ? 7.432 54.240 -3.103 1.00 38.91 ? 422 ASP B C 1 ATOM 7262 O O . ASP B 1 422 ? 6.443 54.655 -3.676 1.00 39.48 ? 422 ASP B O 1 ATOM 7263 C CB . ASP B 1 422 ? 7.123 55.674 -1.113 1.00 40.30 ? 422 ASP B CB 1 ATOM 7264 C CG . ASP B 1 422 ? 7.501 55.388 0.328 1.00 41.72 ? 422 ASP B CG 1 ATOM 7265 O OD1 . ASP B 1 422 ? 7.829 54.224 0.660 1.00 41.78 ? 422 ASP B OD1 1 ATOM 7266 O OD2 . ASP B 1 422 ? 7.440 56.343 1.133 1.00 42.68 ? 422 ASP B OD2 1 ATOM 7267 N N . LEU B 1 423 ? 7.933 53.028 -3.314 1.00 38.14 ? 423 LEU B N 1 ATOM 7268 C CA . LEU B 1 423 ? 7.303 52.080 -4.235 1.00 37.36 ? 423 LEU B CA 1 ATOM 7269 C C . LEU B 1 423 ? 7.644 50.686 -3.743 1.00 36.66 ? 423 LEU B C 1 ATOM 7270 O O . LEU B 1 423 ? 8.679 50.495 -3.105 1.00 37.28 ? 423 LEU B O 1 ATOM 7271 C CB . LEU B 1 423 ? 7.776 52.313 -5.681 1.00 37.71 ? 423 LEU B CB 1 ATOM 7272 C CG . LEU B 1 423 ? 7.227 53.622 -6.299 1.00 38.15 ? 423 LEU B CG 1 ATOM 7273 C CD1 . LEU B 1 423 ? 7.508 53.663 -7.788 1.00 38.00 ? 423 LEU B CD1 1 ATOM 7274 C CD2 . LEU B 1 423 ? 5.711 53.738 -6.082 1.00 38.10 ? 423 LEU B CD2 1 ATOM 7275 N N . PRO B 1 424 ? 6.789 49.690 -4.036 1.00 36.00 ? 424 PRO B N 1 ATOM 7276 C CA . PRO B 1 424 ? 7.105 48.343 -3.545 1.00 35.06 ? 424 PRO B CA 1 ATOM 7277 C C . PRO B 1 424 ? 8.317 47.621 -4.106 1.00 34.24 ? 424 PRO B C 1 ATOM 7278 O O . PRO B 1 424 ? 8.568 47.600 -5.315 1.00 33.89 ? 424 PRO B O 1 ATOM 7279 C CB . PRO B 1 424 ? 5.827 47.539 -3.814 1.00 34.90 ? 424 PRO B CB 1 ATOM 7280 C CG . PRO B 1 424 ? 4.860 48.501 -4.533 1.00 35.49 ? 424 PRO B CG 1 ATOM 7281 C CD . PRO B 1 424 ? 5.697 49.655 -5.024 1.00 35.60 ? 424 PRO B CD 1 ATOM 7282 N N . GLY B 1 425 ? 9.042 46.980 -3.197 1.00 32.88 ? 425 GLY B N 1 ATOM 7283 C CA . GLY B 1 425 ? 10.223 46.214 -3.570 1.00 29.58 ? 425 GLY B CA 1 ATOM 7284 C C . GLY B 1 425 ? 11.444 46.874 -4.212 1.00 27.14 ? 425 GLY B C 1 ATOM 7285 O O . GLY B 1 425 ? 12.105 47.745 -3.631 1.00 27.67 ? 425 GLY B O 1 ATOM 7286 N N . VAL B 1 426 ? 11.771 46.413 -5.417 1.00 23.94 ? 426 VAL B N 1 ATOM 7287 C CA . VAL B 1 426 ? 12.922 46.924 -6.156 1.00 21.59 ? 426 VAL B CA 1 ATOM 7288 C C . VAL B 1 426 ? 12.571 48.202 -6.904 1.00 21.01 ? 426 VAL B C 1 ATOM 7289 O O . VAL B 1 426 ? 13.416 48.794 -7.567 1.00 21.60 ? 426 VAL B O 1 ATOM 7290 C CB . VAL B 1 426 ? 13.445 45.874 -7.174 1.00 19.52 ? 426 VAL B CB 1 ATOM 7291 C CG1 . VAL B 1 426 ? 13.670 44.546 -6.479 1.00 17.84 ? 426 VAL B CG1 1 ATOM 7292 C CG2 . VAL B 1 426 ? 12.453 45.711 -8.340 1.00 18.67 ? 426 VAL B CG2 1 ATOM 7293 N N . GLU B 1 427 ? 11.317 48.624 -6.798 1.00 21.70 ? 427 GLU B N 1 ATOM 7294 C CA . GLU B 1 427 ? 10.869 49.841 -7.471 1.00 22.53 ? 427 GLU B CA 1 ATOM 7295 C C . GLU B 1 427 ? 11.067 51.088 -6.609 1.00 21.44 ? 427 GLU B C 1 ATOM 7296 O O . GLU B 1 427 ? 11.061 51.012 -5.387 1.00 20.73 ? 427 GLU B O 1 ATOM 7297 C CB . GLU B 1 427 ? 9.388 49.722 -7.884 1.00 24.92 ? 427 GLU B CB 1 ATOM 7298 C CG . GLU B 1 427 ? 9.103 48.634 -8.912 1.00 30.28 ? 427 GLU B CG 1 ATOM 7299 C CD . GLU B 1 427 ? 7.669 48.644 -9.399 1.00 33.70 ? 427 GLU B CD 1 ATOM 7300 O OE1 . GLU B 1 427 ? 7.225 49.695 -9.917 1.00 36.21 ? 427 GLU B OE1 1 ATOM 7301 O OE2 . GLU B 1 427 ? 6.995 47.598 -9.267 1.00 35.19 ? 427 GLU B OE2 1 ATOM 7302 N N . GLY B 1 428 ? 11.249 52.238 -7.251 1.00 19.72 ? 428 GLY B N 1 ATOM 7303 C CA . GLY B 1 428 ? 11.442 53.471 -6.505 1.00 18.92 ? 428 GLY B CA 1 ATOM 7304 C C . GLY B 1 428 ? 12.813 54.113 -6.612 1.00 17.42 ? 428 GLY B C 1 ATOM 7305 O O . GLY B 1 428 ? 13.004 55.239 -6.163 1.00 16.88 ? 428 GLY B O 1 ATOM 7306 N N . PHE B 1 429 ? 13.770 53.414 -7.213 1.00 16.91 ? 429 PHE B N 1 ATOM 7307 C CA . PHE B 1 429 ? 15.113 53.965 -7.371 1.00 16.65 ? 429 PHE B CA 1 ATOM 7308 C C . PHE B 1 429 ? 15.281 54.696 -8.687 1.00 16.39 ? 429 PHE B C 1 ATOM 7309 O O . PHE B 1 429 ? 14.524 54.477 -9.628 1.00 17.29 ? 429 PHE B O 1 ATOM 7310 C CB . PHE B 1 429 ? 16.185 52.864 -7.332 1.00 15.16 ? 429 PHE B CB 1 ATOM 7311 C CG . PHE B 1 429 ? 16.309 52.171 -6.002 1.00 15.50 ? 429 PHE B CG 1 ATOM 7312 C CD1 . PHE B 1 429 ? 15.611 50.993 -5.748 1.00 14.99 ? 429 PHE B CD1 1 ATOM 7313 C CD2 . PHE B 1 429 ? 17.158 52.678 -5.019 1.00 14.62 ? 429 PHE B CD2 1 ATOM 7314 C CE1 . PHE B 1 429 ? 15.749 50.327 -4.525 1.00 13.35 ? 429 PHE B CE1 1 ATOM 7315 C CE2 . PHE B 1 429 ? 17.312 52.031 -3.791 1.00 14.22 ? 429 PHE B CE2 1 ATOM 7316 C CZ . PHE B 1 429 ? 16.606 50.839 -3.543 1.00 12.51 ? 429 PHE B CZ 1 ATOM 7317 N N . ASN B 1 430 ? 16.280 55.570 -8.735 1.00 15.95 ? 430 ASN B N 1 ATOM 7318 C CA . ASN B 1 430 ? 16.624 56.293 -9.951 1.00 16.82 ? 430 ASN B CA 1 ATOM 7319 C C . ASN B 1 430 ? 17.723 55.393 -10.496 1.00 15.91 ? 430 ASN B C 1 ATOM 7320 O O . ASN B 1 430 ? 18.873 55.470 -10.059 1.00 15.96 ? 430 ASN B O 1 ATOM 7321 C CB . ASN B 1 430 ? 17.181 57.684 -9.621 1.00 17.26 ? 430 ASN B CB 1 ATOM 7322 C CG . ASN B 1 430 ? 17.603 58.460 -10.860 1.00 18.71 ? 430 ASN B CG 1 ATOM 7323 O OD1 . ASN B 1 430 ? 18.026 59.615 -10.766 1.00 20.42 ? 430 ASN B OD1 1 ATOM 7324 N ND2 . ASN B 1 430 ? 17.494 57.831 -12.025 1.00 18.05 ? 430 ASN B ND2 1 ATOM 7325 N N . ILE B 1 431 ? 17.352 54.516 -11.424 1.00 14.82 ? 431 ILE B N 1 ATOM 7326 C CA . ILE B 1 431 ? 18.291 53.564 -12.006 1.00 14.09 ? 431 ILE B CA 1 ATOM 7327 C C . ILE B 1 431 ? 19.011 54.088 -13.240 1.00 14.75 ? 431 ILE B C 1 ATOM 7328 O O . ILE B 1 431 ? 18.393 54.673 -14.131 1.00 15.57 ? 431 ILE B O 1 ATOM 7329 C CB . ILE B 1 431 ? 17.566 52.247 -12.407 1.00 14.65 ? 431 ILE B CB 1 ATOM 7330 C CG1 . ILE B 1 431 ? 16.855 51.642 -11.193 1.00 15.66 ? 431 ILE B CG1 1 ATOM 7331 C CG2 . ILE B 1 431 ? 18.564 51.251 -13.001 1.00 15.75 ? 431 ILE B CG2 1 ATOM 7332 C CD1 . ILE B 1 431 ? 17.783 51.203 -10.083 1.00 15.18 ? 431 ILE B CD1 1 ATOM 7333 N N . LEU B 1 432 ? 20.322 53.878 -13.277 1.00 13.40 ? 432 LEU B N 1 ATOM 7334 C CA . LEU B 1 432 ? 21.137 54.272 -14.420 1.00 13.59 ? 432 LEU B CA 1 ATOM 7335 C C . LEU B 1 432 ? 21.425 52.983 -15.182 1.00 14.61 ? 432 LEU B C 1 ATOM 7336 O O . LEU B 1 432 ? 22.056 52.074 -14.646 1.00 14.79 ? 432 LEU B O 1 ATOM 7337 C CB . LEU B 1 432 ? 22.460 54.890 -13.965 1.00 15.41 ? 432 LEU B CB 1 ATOM 7338 C CG . LEU B 1 432 ? 23.431 55.216 -15.102 1.00 16.13 ? 432 LEU B CG 1 ATOM 7339 C CD1 . LEU B 1 432 ? 22.892 56.399 -15.896 1.00 17.81 ? 432 LEU B CD1 1 ATOM 7340 C CD2 . LEU B 1 432 ? 24.808 55.540 -14.540 1.00 18.49 ? 432 LEU B CD2 1 ATOM 7341 N N . GLY B 1 433 ? 20.965 52.899 -16.424 1.00 14.38 ? 433 GLY B N 1 ATOM 7342 C CA . GLY B 1 433 ? 21.195 51.695 -17.202 1.00 13.81 ? 433 GLY B CA 1 ATOM 7343 C C . GLY B 1 433 ? 20.011 50.745 -17.164 1.00 13.95 ? 433 GLY B C 1 ATOM 7344 O O . GLY B 1 433 ? 18.886 51.155 -16.882 1.00 13.97 ? 433 GLY B O 1 ATOM 7345 N N . ILE B 1 434 ? 20.269 49.468 -17.435 1.00 12.85 ? 434 ILE B N 1 ATOM 7346 C CA . ILE B 1 434 ? 19.221 48.449 -17.458 1.00 12.82 ? 434 ILE B CA 1 ATOM 7347 C C . ILE B 1 434 ? 18.754 48.042 -16.061 1.00 12.11 ? 434 ILE B C 1 ATOM 7348 O O . ILE B 1 434 ? 19.545 47.568 -15.248 1.00 11.79 ? 434 ILE B O 1 ATOM 7349 C CB . ILE B 1 434 ? 19.705 47.184 -18.200 1.00 13.51 ? 434 ILE B CB 1 ATOM 7350 C CG1 . ILE B 1 434 ? 20.201 47.565 -19.599 1.00 13.34 ? 434 ILE B CG1 1 ATOM 7351 C CG2 . ILE B 1 434 ? 18.572 46.160 -18.282 1.00 12.60 ? 434 ILE B CG2 1 ATOM 7352 C CD1 . ILE B 1 434 ? 20.831 46.423 -20.365 1.00 14.39 ? 434 ILE B CD1 1 ATOM 7353 N N . PRO B 1 435 ? 17.453 48.212 -15.770 1.00 11.40 ? 435 PRO B N 1 ATOM 7354 C CA . PRO B 1 435 ? 16.918 47.849 -14.456 1.00 11.44 ? 435 PRO B CA 1 ATOM 7355 C C . PRO B 1 435 ? 16.589 46.364 -14.351 1.00 10.99 ? 435 PRO B C 1 ATOM 7356 O O . PRO B 1 435 ? 16.517 45.664 -15.361 1.00 10.87 ? 435 PRO B O 1 ATOM 7357 C CB . PRO B 1 435 ? 15.667 48.709 -14.355 1.00 12.25 ? 435 PRO B CB 1 ATOM 7358 C CG . PRO B 1 435 ? 15.158 48.669 -15.761 1.00 12.49 ? 435 PRO B CG 1 ATOM 7359 C CD . PRO B 1 435 ? 16.420 48.878 -16.587 1.00 12.36 ? 435 PRO B CD 1 ATOM 7360 N N . LEU B 1 436 ? 16.393 45.889 -13.124 1.00 10.68 ? 436 LEU B N 1 ATOM 7361 C CA . LEU B 1 436 ? 16.042 44.491 -12.900 1.00 11.06 ? 436 LEU B CA 1 ATOM 7362 C C . LEU B 1 436 ? 14.601 44.277 -13.307 1.00 12.04 ? 436 LEU B C 1 ATOM 7363 O O . LEU B 1 436 ? 13.813 45.223 -13.361 1.00 13.21 ? 436 LEU B O 1 ATOM 7364 C CB . LEU B 1 436 ? 16.131 44.120 -11.417 1.00 11.80 ? 436 LEU B CB 1 ATOM 7365 C CG . LEU B 1 436 ? 17.453 43.997 -10.674 1.00 12.81 ? 436 LEU B CG 1 ATOM 7366 C CD1 . LEU B 1 436 ? 17.152 43.603 -9.229 1.00 13.44 ? 436 LEU B CD1 1 ATOM 7367 C CD2 . LEU B 1 436 ? 18.340 42.958 -11.341 1.00 12.68 ? 436 LEU B CD2 1 ATOM 7368 N N . PRO B 1 437 ? 14.236 43.027 -13.618 1.00 12.36 ? 437 PRO B N 1 ATOM 7369 C CA . PRO B 1 437 ? 12.843 42.783 -13.992 1.00 12.63 ? 437 PRO B CA 1 ATOM 7370 C C . PRO B 1 437 ? 12.042 43.099 -12.726 1.00 13.59 ? 437 PRO B C 1 ATOM 7371 O O . PRO B 1 437 ? 12.543 42.898 -11.621 1.00 14.06 ? 437 PRO B O 1 ATOM 7372 C CB . PRO B 1 437 ? 12.834 41.292 -14.310 1.00 12.90 ? 437 PRO B CB 1 ATOM 7373 C CG . PRO B 1 437 ? 14.214 41.060 -14.857 1.00 12.63 ? 437 PRO B CG 1 ATOM 7374 C CD . PRO B 1 437 ? 15.078 41.848 -13.898 1.00 10.51 ? 437 PRO B CD 1 ATOM 7375 N N . LYS B 1 438 ? 10.819 43.596 -12.871 1.00 14.40 ? 438 LYS B N 1 ATOM 7376 C CA . LYS B 1 438 ? 10.002 43.922 -11.703 1.00 15.52 ? 438 LYS B CA 1 ATOM 7377 C C . LYS B 1 438 ? 9.620 42.677 -10.907 1.00 14.77 ? 438 LYS B C 1 ATOM 7378 O O . LYS B 1 438 ? 9.699 42.661 -9.675 1.00 15.42 ? 438 LYS B O 1 ATOM 7379 C CB . LYS B 1 438 ? 8.748 44.680 -12.147 1.00 18.59 ? 438 LYS B CB 1 ATOM 7380 C CG . LYS B 1 438 ? 9.046 46.070 -12.686 1.00 22.70 ? 438 LYS B CG 1 ATOM 7381 C CD . LYS B 1 438 ? 7.858 46.654 -13.437 1.00 26.42 ? 438 LYS B CD 1 ATOM 7382 C CE . LYS B 1 438 ? 7.592 45.885 -14.728 1.00 28.52 ? 438 LYS B CE 1 ATOM 7383 N NZ . LYS B 1 438 ? 6.490 46.478 -15.536 1.00 31.11 ? 438 LYS B NZ 1 ATOM 7384 N N . ASP B 1 439 ? 9.220 41.631 -11.622 1.00 13.82 ? 439 ASP B N 1 ATOM 7385 C CA . ASP B 1 439 ? 8.815 40.364 -11.017 1.00 13.88 ? 439 ASP B CA 1 ATOM 7386 C C . ASP B 1 439 ? 10.044 39.555 -10.604 1.00 13.54 ? 439 ASP B C 1 ATOM 7387 O O . ASP B 1 439 ? 10.760 39.025 -11.453 1.00 13.53 ? 439 ASP B O 1 ATOM 7388 C CB . ASP B 1 439 ? 7.976 39.570 -12.026 1.00 13.01 ? 439 ASP B CB 1 ATOM 7389 C CG . ASP B 1 439 ? 7.481 38.242 -11.476 1.00 13.97 ? 439 ASP B CG 1 ATOM 7390 O OD1 . ASP B 1 439 ? 7.913 37.826 -10.378 1.00 11.71 ? 439 ASP B OD1 1 ATOM 7391 O OD2 . ASP B 1 439 ? 6.651 37.605 -12.162 1.00 13.55 ? 439 ASP B OD2 1 ATOM 7392 N N . GLN B 1 440 ? 10.276 39.449 -9.298 1.00 12.68 ? 440 GLN B N 1 ATOM 7393 C CA . GLN B 1 440 ? 11.436 38.726 -8.791 1.00 12.17 ? 440 GLN B CA 1 ATOM 7394 C C . GLN B 1 440 ? 11.379 37.209 -8.953 1.00 11.68 ? 440 GLN B C 1 ATOM 7395 O O . GLN B 1 440 ? 12.339 36.512 -8.615 1.00 13.14 ? 440 GLN B O 1 ATOM 7396 C CB . GLN B 1 440 ? 11.679 39.094 -7.324 1.00 12.02 ? 440 GLN B CB 1 ATOM 7397 C CG . GLN B 1 440 ? 11.910 40.586 -7.105 1.00 11.96 ? 440 GLN B CG 1 ATOM 7398 C CD . GLN B 1 440 ? 13.054 41.136 -7.947 1.00 12.58 ? 440 GLN B CD 1 ATOM 7399 O OE1 . GLN B 1 440 ? 14.227 40.860 -7.685 1.00 12.40 ? 440 GLN B OE1 1 ATOM 7400 N NE2 . GLN B 1 440 ? 12.713 41.913 -8.970 1.00 12.84 ? 440 GLN B NE2 1 ATOM 7401 N N . THR B 1 441 ? 10.267 36.699 -9.478 1.00 12.28 ? 441 THR B N 1 ATOM 7402 C CA . THR B 1 441 ? 10.112 35.261 -9.699 1.00 12.37 ? 441 THR B CA 1 ATOM 7403 C C . THR B 1 441 ? 10.133 34.904 -11.188 1.00 12.43 ? 441 THR B C 1 ATOM 7404 O O . THR B 1 441 ? 9.981 33.738 -11.548 1.00 14.32 ? 441 THR B O 1 ATOM 7405 C CB . THR B 1 441 ? 8.784 34.724 -9.114 1.00 13.27 ? 441 THR B CB 1 ATOM 7406 O OG1 . THR B 1 441 ? 7.677 35.299 -9.823 1.00 12.41 ? 441 THR B OG1 1 ATOM 7407 C CG2 . THR B 1 441 ? 8.674 35.059 -7.636 1.00 13.66 ? 441 THR B CG2 1 ATOM 7408 N N . ASP B 1 442 ? 10.320 35.904 -12.045 1.00 11.81 ? 442 ASP B N 1 ATOM 7409 C CA . ASP B 1 442 ? 10.347 35.688 -13.495 1.00 12.97 ? 442 ASP B CA 1 ATOM 7410 C C . ASP B 1 442 ? 11.756 35.318 -13.964 1.00 11.57 ? 442 ASP B C 1 ATOM 7411 O O . ASP B 1 442 ? 12.515 36.173 -14.427 1.00 11.38 ? 442 ASP B O 1 ATOM 7412 C CB . ASP B 1 442 ? 9.882 36.952 -14.220 1.00 12.83 ? 442 ASP B CB 1 ATOM 7413 C CG . ASP B 1 442 ? 9.569 36.706 -15.686 1.00 15.07 ? 442 ASP B CG 1 ATOM 7414 O OD1 . ASP B 1 442 ? 10.040 35.690 -16.238 1.00 14.88 ? 442 ASP B OD1 1 ATOM 7415 O OD2 . ASP B 1 442 ? 8.861 37.538 -16.288 1.00 17.28 ? 442 ASP B OD2 1 ATOM 7416 N N . ASP B 1 443 ? 12.093 34.038 -13.853 1.00 12.15 ? 443 ASP B N 1 ATOM 7417 C CA . ASP B 1 443 ? 13.410 33.548 -14.245 1.00 12.16 ? 443 ASP B CA 1 ATOM 7418 C C . ASP B 1 443 ? 13.784 33.871 -15.687 1.00 10.61 ? 443 ASP B C 1 ATOM 7419 O O . ASP B 1 443 ? 14.919 34.256 -15.967 1.00 10.70 ? 443 ASP B O 1 ATOM 7420 C CB . ASP B 1 443 ? 13.490 32.035 -14.013 1.00 13.73 ? 443 ASP B CB 1 ATOM 7421 C CG . ASP B 1 443 ? 13.472 31.670 -12.535 1.00 16.50 ? 443 ASP B CG 1 ATOM 7422 O OD1 . ASP B 1 443 ? 13.166 32.551 -11.706 1.00 17.03 ? 443 ASP B OD1 1 ATOM 7423 O OD2 . ASP B 1 443 ? 13.757 30.502 -12.203 1.00 19.85 ? 443 ASP B OD2 1 ATOM 7424 N N . ALA B 1 444 ? 12.841 33.715 -16.609 1.00 11.16 ? 444 ALA B N 1 ATOM 7425 C CA . ALA B 1 444 ? 13.127 34.006 -18.009 1.00 10.43 ? 444 ALA B CA 1 ATOM 7426 C C . ALA B 1 444 ? 13.545 35.460 -18.195 1.00 10.95 ? 444 ALA B C 1 ATOM 7427 O O . ALA B 1 444 ? 14.434 35.759 -18.991 1.00 11.02 ? 444 ALA B O 1 ATOM 7428 C CB . ALA B 1 444 ? 11.908 33.696 -18.871 1.00 12.06 ? 444 ALA B CB 1 ATOM 7429 N N . ALA B 1 445 ? 12.900 36.364 -17.465 1.00 10.29 ? 445 ALA B N 1 ATOM 7430 C CA . ALA B 1 445 ? 13.223 37.783 -17.562 1.00 10.32 ? 445 ALA B CA 1 ATOM 7431 C C . ALA B 1 445 ? 14.614 38.057 -16.995 1.00 11.15 ? 445 ALA B C 1 ATOM 7432 O O . ALA B 1 445 ? 15.356 38.882 -17.532 1.00 10.22 ? 445 ALA B O 1 ATOM 7433 C CB . ALA B 1 445 ? 12.181 38.613 -16.825 1.00 11.54 ? 445 ALA B CB 1 ATOM 7434 N N . PHE B 1 446 ? 14.963 37.370 -15.909 1.00 10.12 ? 446 PHE B N 1 ATOM 7435 C CA . PHE B 1 446 ? 16.282 37.544 -15.306 1.00 9.46 ? 446 PHE B CA 1 ATOM 7436 C C . PHE B 1 446 ? 17.372 36.981 -16.217 1.00 9.49 ? 446 PHE B C 1 ATOM 7437 O O . PHE B 1 446 ? 18.489 37.491 -16.245 1.00 8.53 ? 446 PHE B O 1 ATOM 7438 C CB . PHE B 1 446 ? 16.353 36.874 -13.927 1.00 10.56 ? 446 PHE B CB 1 ATOM 7439 C CG . PHE B 1 446 ? 15.885 37.754 -12.799 1.00 9.73 ? 446 PHE B CG 1 ATOM 7440 C CD1 . PHE B 1 446 ? 14.530 37.978 -12.584 1.00 11.90 ? 446 PHE B CD1 1 ATOM 7441 C CD2 . PHE B 1 446 ? 16.807 38.378 -11.962 1.00 9.77 ? 446 PHE B CD2 1 ATOM 7442 C CE1 . PHE B 1 446 ? 14.100 38.813 -11.550 1.00 11.88 ? 446 PHE B CE1 1 ATOM 7443 C CE2 . PHE B 1 446 ? 16.389 39.213 -10.929 1.00 9.80 ? 446 PHE B CE2 1 ATOM 7444 C CZ . PHE B 1 446 ? 15.035 39.432 -10.722 1.00 11.43 ? 446 PHE B CZ 1 ATOM 7445 N N . GLU B 1 447 ? 17.057 35.926 -16.961 1.00 9.03 ? 447 GLU B N 1 ATOM 7446 C CA . GLU B 1 447 ? 18.042 35.361 -17.873 1.00 9.53 ? 447 GLU B CA 1 ATOM 7447 C C . GLU B 1 447 ? 18.352 36.366 -18.967 1.00 10.76 ? 447 GLU B C 1 ATOM 7448 O O . GLU B 1 447 ? 19.508 36.556 -19.340 1.00 9.27 ? 447 GLU B O 1 ATOM 7449 C CB . GLU B 1 447 ? 17.522 34.052 -18.476 1.00 11.03 ? 447 GLU B CB 1 ATOM 7450 C CG . GLU B 1 447 ? 17.667 32.865 -17.544 1.00 13.60 ? 447 GLU B CG 1 ATOM 7451 C CD . GLU B 1 447 ? 17.185 31.565 -18.153 1.00 17.22 ? 447 GLU B CD 1 ATOM 7452 O OE1 . GLU B 1 447 ? 17.131 31.467 -19.396 1.00 19.06 ? 447 GLU B OE1 1 ATOM 7453 O OE2 . GLU B 1 447 ? 16.877 30.627 -17.387 1.00 17.26 ? 447 GLU B OE2 1 ATOM 7454 N N . THR B 1 448 ? 17.315 37.015 -19.485 1.00 11.46 ? 448 THR B N 1 ATOM 7455 C CA . THR B 1 448 ? 17.504 38.015 -20.525 1.00 11.50 ? 448 THR B CA 1 ATOM 7456 C C . THR B 1 448 ? 18.315 39.181 -19.971 1.00 11.59 ? 448 THR B C 1 ATOM 7457 O O . THR B 1 448 ? 19.194 39.716 -20.650 1.00 11.55 ? 448 THR B O 1 ATOM 7458 C CB . THR B 1 448 ? 16.151 38.529 -21.054 1.00 13.86 ? 448 THR B CB 1 ATOM 7459 O OG1 . THR B 1 448 ? 15.468 37.455 -21.710 1.00 15.36 ? 448 THR B OG1 1 ATOM 7460 C CG2 . THR B 1 448 ? 16.357 39.676 -22.036 1.00 14.55 ? 448 THR B CG2 1 ATOM 7461 N N . PHE B 1 449 ? 18.018 39.569 -18.733 1.00 10.79 ? 449 PHE B N 1 ATOM 7462 C CA . PHE B 1 449 ? 18.740 40.656 -18.074 1.00 10.02 ? 449 PHE B CA 1 ATOM 7463 C C . PHE B 1 449 ? 20.217 40.295 -17.985 1.00 11.25 ? 449 PHE B C 1 ATOM 7464 O O . PHE B 1 449 ? 21.089 41.084 -18.349 1.00 9.23 ? 449 PHE B O 1 ATOM 7465 C CB . PHE B 1 449 ? 18.204 40.877 -16.655 1.00 11.60 ? 449 PHE B CB 1 ATOM 7466 C CG . PHE B 1 449 ? 19.034 41.832 -15.839 1.00 10.94 ? 449 PHE B CG 1 ATOM 7467 C CD1 . PHE B 1 449 ? 18.808 43.204 -15.902 1.00 11.86 ? 449 PHE B CD1 1 ATOM 7468 C CD2 . PHE B 1 449 ? 20.076 41.361 -15.042 1.00 9.43 ? 449 PHE B CD2 1 ATOM 7469 C CE1 . PHE B 1 449 ? 19.610 44.095 -15.184 1.00 11.70 ? 449 PHE B CE1 1 ATOM 7470 C CE2 . PHE B 1 449 ? 20.884 42.242 -14.323 1.00 9.64 ? 449 PHE B CE2 1 ATOM 7471 C CZ . PHE B 1 449 ? 20.653 43.612 -14.393 1.00 9.33 ? 449 PHE B CZ 1 ATOM 7472 N N . CYS B 1 450 ? 20.489 39.092 -17.491 1.00 9.93 ? 450 CYS B N 1 ATOM 7473 C CA . CYS B 1 450 ? 21.857 38.618 -17.350 1.00 10.11 ? 450 CYS B CA 1 ATOM 7474 C C . CYS B 1 450 ? 22.637 38.651 -18.658 1.00 10.92 ? 450 CYS B C 1 ATOM 7475 O O . CYS B 1 450 ? 23.748 39.177 -18.720 1.00 11.98 ? 450 CYS B O 1 ATOM 7476 C CB . CYS B 1 450 ? 21.853 37.197 -16.776 1.00 9.10 ? 450 CYS B CB 1 ATOM 7477 S SG . CYS B 1 450 ? 21.554 37.161 -14.975 1.00 11.15 ? 450 CYS B SG 1 ATOM 7478 N N . ARG B 1 451 ? 22.046 38.092 -19.705 1.00 10.54 ? 451 ARG B N 1 ATOM 7479 C CA . ARG B 1 451 ? 22.695 38.044 -21.006 1.00 9.73 ? 451 ARG B CA 1 ATOM 7480 C C . ARG B 1 451 ? 22.916 39.402 -21.652 1.00 10.55 ? 451 ARG B C 1 ATOM 7481 O O . ARG B 1 451 ? 23.990 39.675 -22.181 1.00 11.24 ? 451 ARG B O 1 ATOM 7482 C CB . ARG B 1 451 ? 21.886 37.174 -21.977 1.00 9.37 ? 451 ARG B CB 1 ATOM 7483 C CG . ARG B 1 451 ? 21.906 35.678 -21.686 1.00 10.54 ? 451 ARG B CG 1 ATOM 7484 C CD . ARG B 1 451 ? 21.068 34.938 -22.730 1.00 9.92 ? 451 ARG B CD 1 ATOM 7485 N NE . ARG B 1 451 ? 21.052 33.489 -22.546 1.00 10.08 ? 451 ARG B NE 1 ATOM 7486 C CZ . ARG B 1 451 ? 22.072 32.681 -22.823 1.00 9.39 ? 451 ARG B CZ 1 ATOM 7487 N NH1 . ARG B 1 451 ? 23.211 33.174 -23.300 1.00 10.66 ? 451 ARG B NH1 1 ATOM 7488 N NH2 . ARG B 1 451 ? 21.944 31.372 -22.642 1.00 8.80 ? 451 ARG B NH2 1 ATOM 7489 N N . GLU B 1 452 ? 21.909 40.263 -21.598 1.00 10.06 ? 452 GLU B N 1 ATOM 7490 C CA . GLU B 1 452 ? 22.000 41.571 -22.238 1.00 11.34 ? 452 GLU B CA 1 ATOM 7491 C C . GLU B 1 452 ? 22.708 42.696 -21.499 1.00 11.59 ? 452 GLU B C 1 ATOM 7492 O O . GLU B 1 452 ? 23.058 43.709 -22.106 1.00 11.68 ? 452 GLU B O 1 ATOM 7493 C CB . GLU B 1 452 ? 20.604 42.059 -22.603 1.00 11.62 ? 452 GLU B CB 1 ATOM 7494 C CG . GLU B 1 452 ? 19.807 41.093 -23.434 1.00 17.90 ? 452 GLU B CG 1 ATOM 7495 C CD . GLU B 1 452 ? 18.744 41.798 -24.244 1.00 21.81 ? 452 GLU B CD 1 ATOM 7496 O OE1 . GLU B 1 452 ? 17.944 42.564 -23.657 1.00 20.39 ? 452 GLU B OE1 1 ATOM 7497 O OE2 . GLU B 1 452 ? 18.716 41.587 -25.476 1.00 22.50 ? 452 GLU B OE2 1 ATOM 7498 N N . SER B 1 453 ? 22.928 42.531 -20.200 1.00 9.48 ? 453 SER B N 1 ATOM 7499 C CA . SER B 1 453 ? 23.567 43.578 -19.414 1.00 9.13 ? 453 SER B CA 1 ATOM 7500 C C . SER B 1 453 ? 24.944 43.207 -18.891 1.00 9.29 ? 453 SER B C 1 ATOM 7501 O O . SER B 1 453 ? 25.553 43.984 -18.159 1.00 9.15 ? 453 SER B O 1 ATOM 7502 C CB . SER B 1 453 ? 22.679 43.940 -18.220 1.00 9.51 ? 453 SER B CB 1 ATOM 7503 O OG . SER B 1 453 ? 22.639 42.875 -17.281 1.00 11.42 ? 453 SER B OG 1 ATOM 7504 N N . VAL B 1 454 ? 25.434 42.033 -19.278 1.00 8.16 ? 454 VAL B N 1 ATOM 7505 C CA . VAL B 1 454 ? 26.724 41.537 -18.804 1.00 8.34 ? 454 VAL B CA 1 ATOM 7506 C C . VAL B 1 454 ? 27.948 42.402 -19.105 1.00 9.16 ? 454 VAL B C 1 ATOM 7507 O O . VAL B 1 454 ? 28.023 43.077 -20.131 1.00 9.51 ? 454 VAL B O 1 ATOM 7508 C CB . VAL B 1 454 ? 26.981 40.094 -19.332 1.00 8.37 ? 454 VAL B CB 1 ATOM 7509 C CG1 . VAL B 1 454 ? 27.308 40.123 -20.825 1.00 9.10 ? 454 VAL B CG1 1 ATOM 7510 C CG2 . VAL B 1 454 ? 28.101 39.435 -18.537 1.00 9.66 ? 454 VAL B CG2 1 ATOM 7511 N N . ALA B 1 455 ? 28.898 42.377 -18.176 1.00 8.62 ? 455 ALA B N 1 ATOM 7512 C CA . ALA B 1 455 ? 30.154 43.104 -18.296 1.00 7.82 ? 455 ALA B CA 1 ATOM 7513 C C . ALA B 1 455 ? 31.223 42.177 -17.729 1.00 8.44 ? 455 ALA B C 1 ATOM 7514 O O . ALA B 1 455 ? 30.910 41.087 -17.263 1.00 8.44 ? 455 ALA B O 1 ATOM 7515 C CB . ALA B 1 455 ? 30.101 44.398 -17.490 1.00 9.94 ? 455 ALA B CB 1 ATOM 7516 N N . SER B 1 456 ? 32.480 42.593 -17.782 1.00 6.98 ? 456 SER B N 1 ATOM 7517 C CA . SER B 1 456 ? 33.546 41.769 -17.230 1.00 7.53 ? 456 SER B CA 1 ATOM 7518 C C . SER B 1 456 ? 33.851 42.217 -15.807 1.00 8.09 ? 456 SER B C 1 ATOM 7519 O O . SER B 1 456 ? 33.730 43.396 -15.486 1.00 9.82 ? 456 SER B O 1 ATOM 7520 C CB . SER B 1 456 ? 34.814 41.888 -18.076 1.00 8.45 ? 456 SER B CB 1 ATOM 7521 O OG . SER B 1 456 ? 35.905 41.251 -17.431 1.00 8.81 ? 456 SER B OG 1 ATOM 7522 N N . TYR B 1 457 ? 34.239 41.275 -14.953 1.00 9.20 ? 457 TYR B N 1 ATOM 7523 C CA . TYR B 1 457 ? 34.588 41.619 -13.581 1.00 9.97 ? 457 TYR B CA 1 ATOM 7524 C C . TYR B 1 457 ? 36.090 41.912 -13.543 1.00 9.89 ? 457 TYR B C 1 ATOM 7525 O O . TYR B 1 457 ? 36.636 42.277 -12.502 1.00 9.80 ? 457 TYR B O 1 ATOM 7526 C CB . TYR B 1 457 ? 34.256 40.470 -12.619 1.00 11.26 ? 457 TYR B CB 1 ATOM 7527 C CG . TYR B 1 457 ? 33.797 40.965 -11.268 1.00 14.62 ? 457 TYR B CG 1 ATOM 7528 C CD1 . TYR B 1 457 ? 32.441 41.151 -10.995 1.00 13.73 ? 457 TYR B CD1 1 ATOM 7529 C CD2 . TYR B 1 457 ? 34.720 41.337 -10.292 1.00 15.87 ? 457 TYR B CD2 1 ATOM 7530 C CE1 . TYR B 1 457 ? 32.015 41.704 -9.787 1.00 16.71 ? 457 TYR B CE1 1 ATOM 7531 C CE2 . TYR B 1 457 ? 34.306 41.889 -9.083 1.00 18.14 ? 457 TYR B CE2 1 ATOM 7532 C CZ . TYR B 1 457 ? 32.954 42.072 -8.840 1.00 17.72 ? 457 TYR B CZ 1 ATOM 7533 O OH . TYR B 1 457 ? 32.546 42.644 -7.659 1.00 22.26 ? 457 TYR B OH 1 ATOM 7534 N N . TRP B 1 458 ? 36.736 41.749 -14.698 1.00 8.67 ? 458 TRP B N 1 ATOM 7535 C CA . TRP B 1 458 ? 38.170 41.986 -14.881 1.00 9.09 ? 458 TRP B CA 1 ATOM 7536 C C . TRP B 1 458 ? 39.043 40.940 -14.194 1.00 8.46 ? 458 TRP B C 1 ATOM 7537 O O . TRP B 1 458 ? 40.252 41.130 -14.050 1.00 8.22 ? 458 TRP B O 1 ATOM 7538 C CB . TRP B 1 458 ? 38.567 43.369 -14.359 1.00 10.75 ? 458 TRP B CB 1 ATOM 7539 C CG . TRP B 1 458 ? 37.663 44.494 -14.775 1.00 12.91 ? 458 TRP B CG 1 ATOM 7540 C CD1 . TRP B 1 458 ? 37.313 44.846 -16.048 1.00 14.36 ? 458 TRP B CD1 1 ATOM 7541 C CD2 . TRP B 1 458 ? 37.020 45.435 -13.906 1.00 14.35 ? 458 TRP B CD2 1 ATOM 7542 N NE1 . TRP B 1 458 ? 36.492 45.952 -16.024 1.00 14.88 ? 458 TRP B NE1 1 ATOM 7543 C CE2 . TRP B 1 458 ? 36.298 46.333 -14.722 1.00 15.77 ? 458 TRP B CE2 1 ATOM 7544 C CE3 . TRP B 1 458 ? 36.985 45.609 -12.515 1.00 14.53 ? 458 TRP B CE3 1 ATOM 7545 C CZ2 . TRP B 1 458 ? 35.549 47.391 -14.193 1.00 15.59 ? 458 TRP B CZ2 1 ATOM 7546 C CZ3 . TRP B 1 458 ? 36.239 46.662 -11.989 1.00 17.32 ? 458 TRP B CZ3 1 ATOM 7547 C CH2 . TRP B 1 458 ? 35.532 47.538 -12.830 1.00 16.85 ? 458 TRP B CH2 1 ATOM 7548 N N . HIS B 1 459 ? 38.434 39.838 -13.776 1.00 7.56 ? 459 HIS B N 1 ATOM 7549 C CA . HIS B 1 459 ? 39.169 38.784 -13.092 1.00 6.89 ? 459 HIS B CA 1 ATOM 7550 C C . HIS B 1 459 ? 39.439 37.590 -14.000 1.00 8.40 ? 459 HIS B C 1 ATOM 7551 O O . HIS B 1 459 ? 39.542 36.455 -13.528 1.00 9.31 ? 459 HIS B O 1 ATOM 7552 C CB . HIS B 1 459 ? 38.400 38.339 -11.840 1.00 7.44 ? 459 HIS B CB 1 ATOM 7553 C CG . HIS B 1 459 ? 38.246 39.417 -10.807 1.00 6.11 ? 459 HIS B CG 1 ATOM 7554 N ND1 . HIS B 1 459 ? 37.616 39.207 -9.601 1.00 7.24 ? 459 HIS B ND1 1 ATOM 7555 C CD2 . HIS B 1 459 ? 38.637 40.714 -10.808 1.00 7.04 ? 459 HIS B CD2 1 ATOM 7556 C CE1 . HIS B 1 459 ? 37.623 40.329 -8.901 1.00 6.61 ? 459 HIS B CE1 1 ATOM 7557 N NE2 . HIS B 1 459 ? 38.236 41.258 -9.610 1.00 6.26 ? 459 HIS B NE2 1 ATOM 7558 N N . TYR B 1 460 ? 39.556 37.851 -15.301 1.00 7.60 ? 460 TYR B N 1 ATOM 7559 C CA . TYR B 1 460 ? 39.834 36.793 -16.270 1.00 7.42 ? 460 TYR B CA 1 ATOM 7560 C C . TYR B 1 460 ? 41.107 36.059 -15.863 1.00 7.51 ? 460 TYR B C 1 ATOM 7561 O O . TYR B 1 460 ? 41.994 36.628 -15.220 1.00 8.01 ? 460 TYR B O 1 ATOM 7562 C CB . TYR B 1 460 ? 39.961 37.379 -17.682 1.00 6.94 ? 460 TYR B CB 1 ATOM 7563 C CG . TYR B 1 460 ? 40.788 38.641 -17.744 1.00 6.46 ? 460 TYR B CG 1 ATOM 7564 C CD1 . TYR B 1 460 ? 42.180 38.580 -17.774 1.00 6.89 ? 460 TYR B CD1 1 ATOM 7565 C CD2 . TYR B 1 460 ? 40.180 39.900 -17.705 1.00 7.87 ? 460 TYR B CD2 1 ATOM 7566 C CE1 . TYR B 1 460 ? 42.953 39.741 -17.759 1.00 8.32 ? 460 TYR B CE1 1 ATOM 7567 C CE2 . TYR B 1 460 ? 40.943 41.067 -17.688 1.00 7.96 ? 460 TYR B CE2 1 ATOM 7568 C CZ . TYR B 1 460 ? 42.328 40.978 -17.710 1.00 9.47 ? 460 TYR B CZ 1 ATOM 7569 O OH . TYR B 1 460 ? 43.095 42.119 -17.633 1.00 10.31 ? 460 TYR B OH 1 ATOM 7570 N N . HIS B 1 461 ? 41.182 34.787 -16.238 1.00 7.14 ? 461 HIS B N 1 ATOM 7571 C CA . HIS B 1 461 ? 42.308 33.934 -15.885 1.00 8.08 ? 461 HIS B CA 1 ATOM 7572 C C . HIS B 1 461 ? 42.329 32.728 -16.815 1.00 8.23 ? 461 HIS B C 1 ATOM 7573 O O . HIS B 1 461 ? 41.441 32.569 -17.653 1.00 7.72 ? 461 HIS B O 1 ATOM 7574 C CB . HIS B 1 461 ? 42.148 33.452 -14.441 1.00 7.12 ? 461 HIS B CB 1 ATOM 7575 C CG . HIS B 1 461 ? 40.800 32.862 -14.158 1.00 8.06 ? 461 HIS B CG 1 ATOM 7576 N ND1 . HIS B 1 461 ? 39.679 33.634 -13.940 1.00 8.30 ? 461 HIS B ND1 1 ATOM 7577 C CD2 . HIS B 1 461 ? 40.382 31.574 -14.120 1.00 8.54 ? 461 HIS B CD2 1 ATOM 7578 C CE1 . HIS B 1 461 ? 38.628 32.847 -13.782 1.00 8.29 ? 461 HIS B CE1 1 ATOM 7579 N NE2 . HIS B 1 461 ? 39.028 31.593 -13.886 1.00 7.67 ? 461 HIS B NE2 1 ATOM 7580 N N . GLY B 1 462 ? 43.336 31.874 -16.650 1.00 8.19 ? 462 GLY B N 1 ATOM 7581 C CA . GLY B 1 462 ? 43.452 30.691 -17.488 1.00 8.68 ? 462 GLY B CA 1 ATOM 7582 C C . GLY B 1 462 ? 44.293 30.935 -18.728 1.00 8.36 ? 462 GLY B C 1 ATOM 7583 O O . GLY B 1 462 ? 44.909 31.991 -18.869 1.00 9.00 ? 462 GLY B O 1 ATOM 7584 N N . GLY B 1 463 ? 44.328 29.955 -19.626 1.00 8.33 ? 463 GLY B N 1 ATOM 7585 C CA . GLY B 1 463 ? 45.104 30.097 -20.848 1.00 7.60 ? 463 GLY B CA 1 ATOM 7586 C C . GLY B 1 463 ? 46.402 29.310 -20.875 1.00 9.38 ? 463 GLY B C 1 ATOM 7587 O O . GLY B 1 463 ? 47.006 29.129 -21.934 1.00 10.50 ? 463 GLY B O 1 ATOM 7588 N N . CYS B 1 464 ? 46.842 28.846 -19.710 1.00 8.44 ? 464 CYS B N 1 ATOM 7589 C CA . CYS B 1 464 ? 48.076 28.069 -19.600 1.00 9.28 ? 464 CYS B CA 1 ATOM 7590 C C . CYS B 1 464 ? 47.929 27.257 -18.318 1.00 8.84 ? 464 CYS B C 1 ATOM 7591 O O . CYS B 1 464 ? 48.715 27.389 -17.378 1.00 9.26 ? 464 CYS B O 1 ATOM 7592 C CB . CYS B 1 464 ? 49.272 29.014 -19.499 1.00 9.73 ? 464 CYS B CB 1 ATOM 7593 S SG . CYS B 1 464 ? 50.855 28.205 -19.719 1.00 11.31 ? 464 CYS B SG 1 ATOM 7594 N N . LEU B 1 465 ? 46.913 26.402 -18.313 1.00 10.46 ? 465 LEU B N 1 ATOM 7595 C CA . LEU B 1 465 ? 46.552 25.599 -17.150 1.00 10.11 ? 465 LEU B CA 1 ATOM 7596 C C . LEU B 1 465 ? 47.470 24.494 -16.655 1.00 10.73 ? 465 LEU B C 1 ATOM 7597 O O . LEU B 1 465 ? 48.113 23.789 -17.432 1.00 9.36 ? 465 LEU B O 1 ATOM 7598 C CB . LEU B 1 465 ? 45.171 24.971 -17.369 1.00 9.92 ? 465 LEU B CB 1 ATOM 7599 C CG . LEU B 1 465 ? 43.986 25.846 -17.781 1.00 11.58 ? 465 LEU B CG 1 ATOM 7600 C CD1 . LEU B 1 465 ? 42.724 24.999 -17.729 1.00 11.10 ? 465 LEU B CD1 1 ATOM 7601 C CD2 . LEU B 1 465 ? 43.858 27.046 -16.860 1.00 12.38 ? 465 LEU B CD2 1 ATOM 7602 N N . VAL B 1 466 ? 47.506 24.355 -15.335 1.00 10.05 ? 466 VAL B N 1 ATOM 7603 C CA . VAL B 1 466 ? 48.259 23.288 -14.706 1.00 9.50 ? 466 VAL B CA 1 ATOM 7604 C C . VAL B 1 466 ? 47.464 22.055 -15.137 1.00 9.74 ? 466 VAL B C 1 ATOM 7605 O O . VAL B 1 466 ? 46.234 22.040 -15.043 1.00 11.64 ? 466 VAL B O 1 ATOM 7606 C CB . VAL B 1 466 ? 48.227 23.408 -13.162 1.00 10.33 ? 466 VAL B CB 1 ATOM 7607 C CG1 . VAL B 1 466 ? 48.661 22.097 -12.523 1.00 10.34 ? 466 VAL B CG1 1 ATOM 7608 C CG2 . VAL B 1 466 ? 49.147 24.531 -12.715 1.00 8.68 ? 466 VAL B CG2 1 ATOM 7609 N N . GLY B 1 467 ? 48.156 21.039 -15.635 1.00 10.81 ? 467 GLY B N 1 ATOM 7610 C CA . GLY B 1 467 ? 47.470 19.839 -16.077 1.00 11.19 ? 467 GLY B CA 1 ATOM 7611 C C . GLY B 1 467 ? 47.143 19.837 -17.560 1.00 11.41 ? 467 GLY B C 1 ATOM 7612 O O . GLY B 1 467 ? 46.751 18.806 -18.112 1.00 12.44 ? 467 GLY B O 1 ATOM 7613 N N . LYS B 1 468 ? 47.290 20.992 -18.204 1.00 12.39 ? 468 LYS B N 1 ATOM 7614 C CA . LYS B 1 468 ? 47.026 21.127 -19.637 1.00 11.41 ? 468 LYS B CA 1 ATOM 7615 C C . LYS B 1 468 ? 48.309 21.549 -20.350 1.00 11.58 ? 468 LYS B C 1 ATOM 7616 O O . LYS B 1 468 ? 48.653 21.010 -21.404 1.00 12.05 ? 468 LYS B O 1 ATOM 7617 C CB . LYS B 1 468 ? 45.936 22.172 -19.890 1.00 12.83 ? 468 LYS B CB 1 ATOM 7618 C CG . LYS B 1 468 ? 44.585 21.841 -19.279 1.00 14.17 ? 468 LYS B CG 1 ATOM 7619 C CD . LYS B 1 468 ? 43.932 20.655 -19.960 1.00 18.42 ? 468 LYS B CD 1 ATOM 7620 C CE . LYS B 1 468 ? 42.592 20.341 -19.312 1.00 20.71 ? 468 LYS B CE 1 ATOM 7621 N NZ . LYS B 1 468 ? 41.888 19.223 -19.992 1.00 24.08 ? 468 LYS B NZ 1 ATOM 7622 N N . VAL B 1 469 ? 49.007 22.525 -19.774 1.00 11.45 ? 469 VAL B N 1 ATOM 7623 C CA . VAL B 1 469 ? 50.259 23.016 -20.336 1.00 10.35 ? 469 VAL B CA 1 ATOM 7624 C C . VAL B 1 469 ? 51.391 22.874 -19.318 1.00 9.52 ? 469 VAL B C 1 ATOM 7625 O O . VAL B 1 469 ? 52.535 22.603 -19.684 1.00 11.12 ? 469 VAL B O 1 ATOM 7626 C CB . VAL B 1 469 ? 50.157 24.514 -20.734 1.00 10.40 ? 469 VAL B CB 1 ATOM 7627 C CG1 . VAL B 1 469 ? 51.460 24.972 -21.383 1.00 10.88 ? 469 VAL B CG1 1 ATOM 7628 C CG2 . VAL B 1 469 ? 48.988 24.728 -21.687 1.00 11.08 ? 469 VAL B CG2 1 ATOM 7629 N N . LEU B 1 470 ? 51.062 23.056 -18.043 1.00 9.68 ? 470 LEU B N 1 ATOM 7630 C CA . LEU B 1 470 ? 52.049 22.983 -16.965 1.00 9.20 ? 470 LEU B CA 1 ATOM 7631 C C . LEU B 1 470 ? 51.872 21.762 -16.072 1.00 9.98 ? 470 LEU B C 1 ATOM 7632 O O . LEU B 1 470 ? 50.813 21.139 -16.063 1.00 10.67 ? 470 LEU B O 1 ATOM 7633 C CB . LEU B 1 470 ? 51.940 24.227 -16.075 1.00 9.84 ? 470 LEU B CB 1 ATOM 7634 C CG . LEU B 1 470 ? 51.853 25.604 -16.734 1.00 8.90 ? 470 LEU B CG 1 ATOM 7635 C CD1 . LEU B 1 470 ? 51.565 26.656 -15.666 1.00 9.08 ? 470 LEU B CD1 1 ATOM 7636 C CD2 . LEU B 1 470 ? 53.149 25.908 -17.461 1.00 8.19 ? 470 LEU B CD2 1 ATOM 7637 N N . ASP B 1 471 ? 52.914 21.430 -15.314 1.00 11.14 ? 471 ASP B N 1 ATOM 7638 C CA . ASP B 1 471 ? 52.835 20.315 -14.385 1.00 11.77 ? 471 ASP B CA 1 ATOM 7639 C C . ASP B 1 471 ? 52.576 20.903 -12.999 1.00 12.77 ? 471 ASP B C 1 ATOM 7640 O O . ASP B 1 471 ? 52.385 22.114 -12.865 1.00 11.15 ? 471 ASP B O 1 ATOM 7641 C CB . ASP B 1 471 ? 54.125 19.464 -14.424 1.00 12.89 ? 471 ASP B CB 1 ATOM 7642 C CG . ASP B 1 471 ? 55.351 20.184 -13.877 1.00 15.15 ? 471 ASP B CG 1 ATOM 7643 O OD1 . ASP B 1 471 ? 56.462 19.611 -13.983 1.00 16.14 ? 471 ASP B OD1 1 ATOM 7644 O OD2 . ASP B 1 471 ? 55.226 21.305 -13.342 1.00 15.41 ? 471 ASP B OD2 1 ATOM 7645 N N . GLY B 1 472 ? 52.552 20.052 -11.979 1.00 11.56 ? 472 GLY B N 1 ATOM 7646 C CA . GLY B 1 472 ? 52.299 20.508 -10.620 1.00 12.93 ? 472 GLY B CA 1 ATOM 7647 C C . GLY B 1 472 ? 53.324 21.434 -9.988 1.00 11.91 ? 472 GLY B C 1 ATOM 7648 O O . GLY B 1 472 ? 53.095 21.960 -8.896 1.00 13.23 ? 472 GLY B O 1 ATOM 7649 N N . ASP B 1 473 ? 54.448 21.645 -10.663 1.00 12.27 ? 473 ASP B N 1 ATOM 7650 C CA . ASP B 1 473 ? 55.501 22.525 -10.166 1.00 12.47 ? 473 ASP B CA 1 ATOM 7651 C C . ASP B 1 473 ? 55.573 23.761 -11.060 1.00 11.53 ? 473 ASP B C 1 ATOM 7652 O O . ASP B 1 473 ? 56.529 24.532 -11.015 1.00 11.10 ? 473 ASP B O 1 ATOM 7653 C CB . ASP B 1 473 ? 56.842 21.782 -10.161 1.00 17.13 ? 473 ASP B CB 1 ATOM 7654 C CG . ASP B 1 473 ? 56.818 20.548 -9.281 1.00 18.88 ? 473 ASP B CG 1 ATOM 7655 O OD1 . ASP B 1 473 ? 56.527 20.677 -8.073 1.00 22.41 ? 473 ASP B OD1 1 ATOM 7656 O OD2 . ASP B 1 473 ? 57.107 19.451 -9.802 1.00 22.40 ? 473 ASP B OD2 1 ATOM 7657 N N . PHE B 1 474 ? 54.539 23.919 -11.881 1.00 10.62 ? 474 PHE B N 1 ATOM 7658 C CA . PHE B 1 474 ? 54.388 25.033 -12.813 1.00 9.49 ? 474 PHE B CA 1 ATOM 7659 C C . PHE B 1 474 ? 55.367 25.058 -13.989 1.00 8.97 ? 474 PHE B C 1 ATOM 7660 O O . PHE B 1 474 ? 55.535 26.086 -14.652 1.00 8.74 ? 474 PHE B O 1 ATOM 7661 C CB . PHE B 1 474 ? 54.428 26.371 -12.059 1.00 9.99 ? 474 PHE B CB 1 ATOM 7662 C CG . PHE B 1 474 ? 53.306 26.538 -11.067 1.00 8.92 ? 474 PHE B CG 1 ATOM 7663 C CD1 . PHE B 1 474 ? 53.414 26.019 -9.777 1.00 8.78 ? 474 PHE B CD1 1 ATOM 7664 C CD2 . PHE B 1 474 ? 52.108 27.149 -11.443 1.00 8.57 ? 474 PHE B CD2 1 ATOM 7665 C CE1 . PHE B 1 474 ? 52.343 26.099 -8.876 1.00 8.22 ? 474 PHE B CE1 1 ATOM 7666 C CE2 . PHE B 1 474 ? 51.034 27.233 -10.550 1.00 9.37 ? 474 PHE B CE2 1 ATOM 7667 C CZ . PHE B 1 474 ? 51.153 26.705 -9.266 1.00 8.62 ? 474 PHE B CZ 1 ATOM 7668 N N . ARG B 1 475 ? 56.002 23.924 -14.261 1.00 9.04 ? 475 ARG B N 1 ATOM 7669 C CA . ARG B 1 475 ? 56.928 23.851 -15.382 1.00 9.51 ? 475 ARG B CA 1 ATOM 7670 C C . ARG B 1 475 ? 56.129 23.591 -16.653 1.00 9.10 ? 475 ARG B C 1 ATOM 7671 O O . ARG B 1 475 ? 55.113 22.895 -16.618 1.00 9.56 ? 475 ARG B O 1 ATOM 7672 C CB . ARG B 1 475 ? 57.920 22.691 -15.210 1.00 10.30 ? 475 ARG B CB 1 ATOM 7673 C CG . ARG B 1 475 ? 58.762 22.704 -13.949 1.00 12.76 ? 475 ARG B CG 1 ATOM 7674 C CD . ARG B 1 475 ? 59.858 21.638 -14.038 1.00 13.85 ? 475 ARG B CD 1 ATOM 7675 N NE A ARG B 1 475 ? 60.478 21.364 -12.743 0.50 12.93 ? 475 ARG B NE 1 ATOM 7676 N NE B ARG B 1 475 ? 61.153 22.180 -13.581 0.50 13.59 ? 475 ARG B NE 1 ATOM 7677 C CZ A ARG B 1 475 ? 59.938 20.592 -11.805 0.50 13.15 ? 475 ARG B CZ 1 ATOM 7678 C CZ B ARG B 1 475 ? 61.757 21.799 -12.460 0.50 14.09 ? 475 ARG B CZ 1 ATOM 7679 N NH1 A ARG B 1 475 ? 58.764 20.008 -12.013 0.50 11.13 ? 475 ARG B NH1 1 ATOM 7680 N NH1 B ARG B 1 475 ? 61.192 20.891 -11.671 0.50 12.10 ? 475 ARG B NH1 1 ATOM 7681 N NH2 A ARG B 1 475 ? 60.569 20.405 -10.656 0.50 14.21 ? 475 ARG B NH2 1 ATOM 7682 N NH2 B ARG B 1 475 ? 62.926 22.326 -12.124 0.50 15.08 ? 475 ARG B NH2 1 ATOM 7683 N N . VAL B 1 476 ? 56.577 24.159 -17.768 1.00 9.90 ? 476 VAL B N 1 ATOM 7684 C CA . VAL B 1 476 ? 55.921 23.911 -19.048 1.00 9.97 ? 476 VAL B CA 1 ATOM 7685 C C . VAL B 1 476 ? 56.405 22.504 -19.408 1.00 11.11 ? 476 VAL B C 1 ATOM 7686 O O . VAL B 1 476 ? 57.610 22.264 -19.497 1.00 12.36 ? 476 VAL B O 1 ATOM 7687 C CB . VAL B 1 476 ? 56.381 24.916 -20.129 1.00 10.51 ? 476 VAL B CB 1 ATOM 7688 C CG1 . VAL B 1 476 ? 55.879 24.483 -21.500 1.00 10.74 ? 476 VAL B CG1 1 ATOM 7689 C CG2 . VAL B 1 476 ? 55.854 26.310 -19.794 1.00 9.15 ? 476 VAL B CG2 1 ATOM 7690 N N . THR B 1 477 ? 55.476 21.574 -19.595 1.00 11.29 ? 477 THR B N 1 ATOM 7691 C CA . THR B 1 477 ? 55.855 20.198 -19.910 1.00 13.92 ? 477 THR B CA 1 ATOM 7692 C C . THR B 1 477 ? 56.633 20.088 -21.219 1.00 14.24 ? 477 THR B C 1 ATOM 7693 O O . THR B 1 477 ? 56.399 20.847 -22.157 1.00 15.35 ? 477 THR B O 1 ATOM 7694 C CB . THR B 1 477 ? 54.621 19.288 -19.998 1.00 14.78 ? 477 THR B CB 1 ATOM 7695 O OG1 . THR B 1 477 ? 53.781 19.730 -21.067 1.00 17.75 ? 477 THR B OG1 1 ATOM 7696 C CG2 . THR B 1 477 ? 53.836 19.320 -18.691 1.00 14.02 ? 477 THR B CG2 1 ATOM 7697 N N . GLY B 1 478 ? 57.569 19.143 -21.264 1.00 14.58 ? 478 GLY B N 1 ATOM 7698 C CA . GLY B 1 478 ? 58.366 18.931 -22.460 1.00 13.64 ? 478 GLY B CA 1 ATOM 7699 C C . GLY B 1 478 ? 59.523 19.892 -22.655 1.00 15.34 ? 478 GLY B C 1 ATOM 7700 O O . GLY B 1 478 ? 60.322 19.725 -23.578 1.00 15.31 ? 478 GLY B O 1 ATOM 7701 N N . ILE B 1 479 ? 59.628 20.893 -21.786 1.00 14.19 ? 479 ILE B N 1 ATOM 7702 C CA . ILE B 1 479 ? 60.693 21.883 -21.891 1.00 14.68 ? 479 ILE B CA 1 ATOM 7703 C C . ILE B 1 479 ? 61.344 22.133 -20.533 1.00 14.32 ? 479 ILE B C 1 ATOM 7704 O O . ILE B 1 479 ? 60.651 22.246 -19.527 1.00 14.72 ? 479 ILE B O 1 ATOM 7705 C CB . ILE B 1 479 ? 60.134 23.222 -22.424 1.00 14.47 ? 479 ILE B CB 1 ATOM 7706 C CG1 . ILE B 1 479 ? 59.433 22.989 -23.764 1.00 14.97 ? 479 ILE B CG1 1 ATOM 7707 C CG2 . ILE B 1 479 ? 61.256 24.237 -22.573 1.00 15.27 ? 479 ILE B CG2 1 ATOM 7708 C CD1 . ILE B 1 479 ? 58.730 24.209 -24.313 1.00 15.54 ? 479 ILE B CD1 1 ATOM 7709 N N . ASN B 1 480 ? 62.672 22.215 -20.507 1.00 14.70 ? 480 ASN B N 1 ATOM 7710 C CA . ASN B 1 480 ? 63.395 22.471 -19.262 1.00 13.60 ? 480 ASN B CA 1 ATOM 7711 C C . ASN B 1 480 ? 63.641 23.958 -19.058 1.00 13.15 ? 480 ASN B C 1 ATOM 7712 O O . ASN B 1 480 ? 63.631 24.731 -20.012 1.00 12.89 ? 480 ASN B O 1 ATOM 7713 C CB . ASN B 1 480 ? 64.754 21.763 -19.254 1.00 17.22 ? 480 ASN B CB 1 ATOM 7714 C CG . ASN B 1 480 ? 64.640 20.276 -19.454 1.00 17.74 ? 480 ASN B CG 1 ATOM 7715 O OD1 . ASN B 1 480 ? 63.726 19.637 -18.940 1.00 20.89 ? 480 ASN B OD1 1 ATOM 7716 N ND2 . ASN B 1 480 ? 65.589 19.706 -20.187 1.00 22.17 ? 480 ASN B ND2 1 ATOM 7717 N N . ALA B 1 481 ? 63.875 24.341 -17.806 1.00 11.62 ? 481 ALA B N 1 ATOM 7718 C CA . ALA B 1 481 ? 64.165 25.725 -17.437 1.00 11.65 ? 481 ALA B CA 1 ATOM 7719 C C . ALA B 1 481 ? 63.114 26.741 -17.873 1.00 10.65 ? 481 ALA B C 1 ATOM 7720 O O . ALA B 1 481 ? 63.442 27.895 -18.161 1.00 10.73 ? 481 ALA B O 1 ATOM 7721 C CB . ALA B 1 481 ? 65.532 26.130 -17.982 1.00 14.26 ? 481 ALA B CB 1 ATOM 7722 N N . LEU B 1 482 ? 61.855 26.316 -17.904 1.00 10.67 ? 482 LEU B N 1 ATOM 7723 C CA . LEU B 1 482 ? 60.765 27.204 -18.295 1.00 11.12 ? 482 LEU B CA 1 ATOM 7724 C C . LEU B 1 482 ? 59.526 26.962 -17.441 1.00 9.92 ? 482 LEU B C 1 ATOM 7725 O O . LEU B 1 482 ? 59.005 25.848 -17.389 1.00 11.39 ? 482 LEU B O 1 ATOM 7726 C CB . LEU B 1 482 ? 60.405 26.997 -19.768 1.00 10.87 ? 482 LEU B CB 1 ATOM 7727 C CG . LEU B 1 482 ? 59.276 27.889 -20.295 1.00 10.64 ? 482 LEU B CG 1 ATOM 7728 C CD1 . LEU B 1 482 ? 59.719 29.344 -20.252 1.00 11.25 ? 482 LEU B CD1 1 ATOM 7729 C CD2 . LEU B 1 482 ? 58.914 27.488 -21.720 1.00 11.02 ? 482 LEU B CD2 1 ATOM 7730 N N . ARG B 1 483 ? 59.058 28.009 -16.771 1.00 9.45 ? 483 ARG B N 1 ATOM 7731 C CA . ARG B 1 483 ? 57.867 27.903 -15.943 1.00 9.11 ? 483 ARG B CA 1 ATOM 7732 C C . ARG B 1 483 ? 56.944 29.077 -16.222 1.00 8.43 ? 483 ARG B C 1 ATOM 7733 O O . ARG B 1 483 ? 57.327 30.042 -16.887 1.00 9.32 ? 483 ARG B O 1 ATOM 7734 C CB . ARG B 1 483 ? 58.225 27.893 -14.452 1.00 10.04 ? 483 ARG B CB 1 ATOM 7735 C CG . ARG B 1 483 ? 59.277 26.865 -14.070 1.00 10.31 ? 483 ARG B CG 1 ATOM 7736 C CD . ARG B 1 483 ? 59.173 26.467 -12.599 1.00 11.02 ? 483 ARG B CD 1 ATOM 7737 N NE . ARG B 1 483 ? 60.400 25.812 -12.148 1.00 11.78 ? 483 ARG B NE 1 ATOM 7738 C CZ . ARG B 1 483 ? 60.487 25.029 -11.078 1.00 13.66 ? 483 ARG B CZ 1 ATOM 7739 N NH1 . ARG B 1 483 ? 59.415 24.783 -10.335 1.00 14.86 ? 483 ARG B NH1 1 ATOM 7740 N NH2 . ARG B 1 483 ? 61.656 24.500 -10.742 1.00 15.02 ? 483 ARG B NH2 1 ATOM 7741 N N . VAL B 1 484 ? 55.725 28.973 -15.710 1.00 8.18 ? 484 VAL B N 1 ATOM 7742 C CA . VAL B 1 484 ? 54.720 30.016 -15.854 1.00 5.96 ? 484 VAL B CA 1 ATOM 7743 C C . VAL B 1 484 ? 54.111 30.231 -14.473 1.00 7.11 ? 484 VAL B C 1 ATOM 7744 O O . VAL B 1 484 ? 53.683 29.280 -13.822 1.00 7.50 ? 484 VAL B O 1 ATOM 7745 C CB . VAL B 1 484 ? 53.608 29.604 -16.843 1.00 6.23 ? 484 VAL B CB 1 ATOM 7746 C CG1 . VAL B 1 484 ? 52.460 30.609 -16.787 1.00 6.39 ? 484 VAL B CG1 1 ATOM 7747 C CG2 . VAL B 1 484 ? 54.174 29.532 -18.259 1.00 6.89 ? 484 VAL B CG2 1 ATOM 7748 N N . VAL B 1 485 ? 54.098 31.480 -14.017 1.00 7.14 ? 485 VAL B N 1 ATOM 7749 C CA . VAL B 1 485 ? 53.541 31.796 -12.707 1.00 7.41 ? 485 VAL B CA 1 ATOM 7750 C C . VAL B 1 485 ? 52.812 33.135 -12.751 1.00 7.69 ? 485 VAL B C 1 ATOM 7751 O O . VAL B 1 485 ? 53.429 34.196 -12.725 1.00 7.59 ? 485 VAL B O 1 ATOM 7752 C CB . VAL B 1 485 ? 54.649 31.849 -11.619 1.00 8.11 ? 485 VAL B CB 1 ATOM 7753 C CG1 . VAL B 1 485 ? 54.023 32.073 -10.251 1.00 8.60 ? 485 VAL B CG1 1 ATOM 7754 C CG2 . VAL B 1 485 ? 55.446 30.550 -11.618 1.00 8.66 ? 485 VAL B CG2 1 ATOM 7755 N N . ASP B 1 486 ? 51.488 33.062 -12.843 1.00 7.76 ? 486 ASP B N 1 ATOM 7756 C CA . ASP B 1 486 ? 50.613 34.231 -12.885 1.00 7.70 ? 486 ASP B CA 1 ATOM 7757 C C . ASP B 1 486 ? 49.180 33.718 -12.932 1.00 7.60 ? 486 ASP B C 1 ATOM 7758 O O . ASP B 1 486 ? 48.934 32.541 -12.660 1.00 7.42 ? 486 ASP B O 1 ATOM 7759 C CB . ASP B 1 486 ? 50.909 35.114 -14.107 1.00 8.49 ? 486 ASP B CB 1 ATOM 7760 C CG . ASP B 1 486 ? 50.851 34.349 -15.421 1.00 7.91 ? 486 ASP B CG 1 ATOM 7761 O OD1 . ASP B 1 486 ? 50.139 33.326 -15.492 1.00 10.54 ? 486 ASP B OD1 1 ATOM 7762 O OD2 . ASP B 1 486 ? 51.516 34.785 -16.385 1.00 8.86 ? 486 ASP B OD2 1 ATOM 7763 N N . GLY B 1 487 ? 48.234 34.583 -13.286 1.00 7.07 ? 487 GLY B N 1 ATOM 7764 C CA . GLY B 1 487 ? 46.842 34.162 -13.328 1.00 7.04 ? 487 GLY B CA 1 ATOM 7765 C C . GLY B 1 487 ? 46.403 33.249 -14.464 1.00 6.16 ? 487 GLY B C 1 ATOM 7766 O O . GLY B 1 487 ? 45.234 32.886 -14.539 1.00 6.09 ? 487 GLY B O 1 ATOM 7767 N N . SER B 1 488 ? 47.323 32.863 -15.341 1.00 6.99 ? 488 SER B N 1 ATOM 7768 C CA . SER B 1 488 ? 46.970 32.003 -16.469 1.00 6.78 ? 488 SER B CA 1 ATOM 7769 C C . SER B 1 488 ? 46.939 30.514 -16.136 1.00 8.88 ? 488 SER B C 1 ATOM 7770 O O . SER B 1 488 ? 46.513 29.707 -16.964 1.00 7.61 ? 488 SER B O 1 ATOM 7771 C CB . SER B 1 488 ? 47.972 32.204 -17.612 1.00 6.78 ? 488 SER B CB 1 ATOM 7772 O OG . SER B 1 488 ? 49.231 31.617 -17.287 1.00 9.58 ? 488 SER B OG 1 ATOM 7773 N N . THR B 1 489 ? 47.347 30.150 -14.923 1.00 8.70 ? 489 THR B N 1 ATOM 7774 C CA . THR B 1 489 ? 47.459 28.734 -14.571 1.00 8.81 ? 489 THR B CA 1 ATOM 7775 C C . THR B 1 489 ? 46.282 27.912 -14.040 1.00 9.50 ? 489 THR B C 1 ATOM 7776 O O . THR B 1 489 ? 46.391 26.687 -13.960 1.00 9.61 ? 489 THR B O 1 ATOM 7777 C CB . THR B 1 489 ? 48.648 28.523 -13.607 1.00 10.03 ? 489 THR B CB 1 ATOM 7778 O OG1 . THR B 1 489 ? 48.264 28.892 -12.280 1.00 11.46 ? 489 THR B OG1 1 ATOM 7779 C CG2 . THR B 1 489 ? 49.832 29.375 -14.029 1.00 8.88 ? 489 THR B CG2 1 ATOM 7780 N N . PHE B 1 490 ? 45.170 28.542 -13.679 1.00 8.50 ? 490 PHE B N 1 ATOM 7781 C CA . PHE B 1 490 ? 44.024 27.779 -13.177 1.00 8.82 ? 490 PHE B CA 1 ATOM 7782 C C . PHE B 1 490 ? 42.731 28.190 -13.872 1.00 8.54 ? 490 PHE B C 1 ATOM 7783 O O . PHE B 1 490 ? 42.576 29.339 -14.275 1.00 8.55 ? 490 PHE B O 1 ATOM 7784 C CB . PHE B 1 490 ? 43.890 27.943 -11.661 1.00 8.37 ? 490 PHE B CB 1 ATOM 7785 C CG . PHE B 1 490 ? 45.052 27.383 -10.890 1.00 8.85 ? 490 PHE B CG 1 ATOM 7786 C CD1 . PHE B 1 490 ? 45.961 28.226 -10.265 1.00 9.02 ? 490 PHE B CD1 1 ATOM 7787 C CD2 . PHE B 1 490 ? 45.254 26.007 -10.815 1.00 10.02 ? 490 PHE B CD2 1 ATOM 7788 C CE1 . PHE B 1 490 ? 47.058 27.710 -9.575 1.00 10.19 ? 490 PHE B CE1 1 ATOM 7789 C CE2 . PHE B 1 490 ? 46.347 25.479 -10.127 1.00 9.69 ? 490 PHE B CE2 1 ATOM 7790 C CZ . PHE B 1 490 ? 47.252 26.333 -9.506 1.00 9.50 ? 490 PHE B CZ 1 ATOM 7791 N N . PRO B 1 491 ? 41.784 27.250 -14.023 1.00 9.29 ? 491 PRO B N 1 ATOM 7792 C CA . PRO B 1 491 ? 40.506 27.530 -14.686 1.00 9.18 ? 491 PRO B CA 1 ATOM 7793 C C . PRO B 1 491 ? 39.461 28.308 -13.897 1.00 8.76 ? 491 PRO B C 1 ATOM 7794 O O . PRO B 1 491 ? 38.626 28.999 -14.483 1.00 9.41 ? 491 PRO B O 1 ATOM 7795 C CB . PRO B 1 491 ? 40.008 26.138 -15.062 1.00 9.59 ? 491 PRO B CB 1 ATOM 7796 C CG . PRO B 1 491 ? 40.492 25.306 -13.915 1.00 10.15 ? 491 PRO B CG 1 ATOM 7797 C CD . PRO B 1 491 ? 41.910 25.812 -13.714 1.00 9.60 ? 491 PRO B CD 1 ATOM 7798 N N . TYR B 1 492 ? 39.495 28.195 -12.576 1.00 9.10 ? 492 TYR B N 1 ATOM 7799 C CA . TYR B 1 492 ? 38.511 28.881 -11.753 1.00 9.79 ? 492 TYR B CA 1 ATOM 7800 C C . TYR B 1 492 ? 39.138 29.934 -10.853 1.00 9.83 ? 492 TYR B C 1 ATOM 7801 O O . TYR B 1 492 ? 40.315 29.852 -10.502 1.00 11.19 ? 492 TYR B O 1 ATOM 7802 C CB . TYR B 1 492 ? 37.734 27.846 -10.939 1.00 12.04 ? 492 TYR B CB 1 ATOM 7803 C CG . TYR B 1 492 ? 37.099 26.787 -11.818 1.00 9.70 ? 492 TYR B CG 1 ATOM 7804 C CD1 . TYR B 1 492 ? 37.257 25.431 -11.535 1.00 13.88 ? 492 TYR B CD1 1 ATOM 7805 C CD2 . TYR B 1 492 ? 36.367 27.142 -12.954 1.00 10.06 ? 492 TYR B CD2 1 ATOM 7806 C CE1 . TYR B 1 492 ? 36.706 24.454 -12.365 1.00 12.33 ? 492 TYR B CE1 1 ATOM 7807 C CE2 . TYR B 1 492 ? 35.812 26.173 -13.789 1.00 10.18 ? 492 TYR B CE2 1 ATOM 7808 C CZ . TYR B 1 492 ? 35.988 24.833 -13.488 1.00 12.71 ? 492 TYR B CZ 1 ATOM 7809 O OH . TYR B 1 492 ? 35.456 23.873 -14.320 1.00 15.33 ? 492 TYR B OH 1 ATOM 7810 N N . THR B 1 493 ? 38.346 30.939 -10.498 1.00 9.49 ? 493 THR B N 1 ATOM 7811 C CA . THR B 1 493 ? 38.831 32.017 -9.654 1.00 10.00 ? 493 THR B CA 1 ATOM 7812 C C . THR B 1 493 ? 38.973 31.507 -8.213 1.00 8.92 ? 493 THR B C 1 ATOM 7813 O O . THR B 1 493 ? 38.099 30.811 -7.696 1.00 9.47 ? 493 THR B O 1 ATOM 7814 C CB . THR B 1 493 ? 37.874 33.237 -9.751 1.00 9.73 ? 493 THR B CB 1 ATOM 7815 O OG1 . THR B 1 493 ? 38.556 34.415 -9.308 1.00 10.86 ? 493 THR B OG1 1 ATOM 7816 C CG2 . THR B 1 493 ? 36.612 33.017 -8.919 1.00 9.92 ? 493 THR B CG2 1 ATOM 7817 N N . PRO B 1 494 ? 40.092 31.840 -7.552 1.00 9.68 ? 494 PRO B N 1 ATOM 7818 C CA . PRO B 1 494 ? 40.380 31.420 -6.176 1.00 10.20 ? 494 PRO B CA 1 ATOM 7819 C C . PRO B 1 494 ? 39.517 32.045 -5.082 1.00 9.51 ? 494 PRO B C 1 ATOM 7820 O O . PRO B 1 494 ? 39.417 31.507 -3.982 1.00 9.87 ? 494 PRO B O 1 ATOM 7821 C CB . PRO B 1 494 ? 41.850 31.785 -6.014 1.00 9.97 ? 494 PRO B CB 1 ATOM 7822 C CG . PRO B 1 494 ? 41.949 33.048 -6.810 1.00 10.04 ? 494 PRO B CG 1 ATOM 7823 C CD . PRO B 1 494 ? 41.181 32.687 -8.073 1.00 8.70 ? 494 PRO B CD 1 ATOM 7824 N N . ALA B 1 495 ? 38.910 33.185 -5.384 1.00 7.60 ? 495 ALA B N 1 ATOM 7825 C CA . ALA B 1 495 ? 38.066 33.879 -4.420 1.00 8.05 ? 495 ALA B CA 1 ATOM 7826 C C . ALA B 1 495 ? 37.292 34.944 -5.176 1.00 7.10 ? 495 ALA B C 1 ATOM 7827 O O . ALA B 1 495 ? 37.367 35.014 -6.402 1.00 7.95 ? 495 ALA B O 1 ATOM 7828 C CB . ALA B 1 495 ? 38.926 34.523 -3.336 1.00 8.14 ? 495 ALA B CB 1 ATOM 7829 N N . SER B 1 496 ? 36.552 35.773 -4.447 1.00 7.20 ? 496 SER B N 1 ATOM 7830 C CA . SER B 1 496 ? 35.774 36.839 -5.070 1.00 8.10 ? 496 SER B CA 1 ATOM 7831 C C . SER B 1 496 ? 36.713 37.825 -5.758 1.00 9.04 ? 496 SER B C 1 ATOM 7832 O O . SER B 1 496 ? 36.362 38.439 -6.765 1.00 7.89 ? 496 SER B O 1 ATOM 7833 C CB . SER B 1 496 ? 34.950 37.572 -4.011 1.00 8.52 ? 496 SER B CB 1 ATOM 7834 O OG . SER B 1 496 ? 35.794 38.125 -3.015 1.00 9.58 ? 496 SER B OG 1 ATOM 7835 N N . HIS B 1 497 ? 37.911 37.958 -5.197 1.00 8.00 ? 497 HIS B N 1 ATOM 7836 C CA . HIS B 1 497 ? 38.946 38.853 -5.707 1.00 6.90 ? 497 HIS B CA 1 ATOM 7837 C C . HIS B 1 497 ? 40.244 38.048 -5.627 1.00 7.83 ? 497 HIS B C 1 ATOM 7838 O O . HIS B 1 497 ? 40.699 37.684 -4.542 1.00 7.54 ? 497 HIS B O 1 ATOM 7839 C CB . HIS B 1 497 ? 38.979 40.121 -4.852 1.00 7.55 ? 497 HIS B CB 1 ATOM 7840 C CG . HIS B 1 497 ? 37.706 40.909 -4.917 1.00 7.56 ? 497 HIS B CG 1 ATOM 7841 N ND1 . HIS B 1 497 ? 36.556 40.532 -4.251 1.00 9.92 ? 497 HIS B ND1 1 ATOM 7842 C CD2 . HIS B 1 497 ? 37.385 42.027 -5.611 1.00 8.10 ? 497 HIS B CD2 1 ATOM 7843 C CE1 . HIS B 1 497 ? 35.586 41.382 -4.534 1.00 9.00 ? 497 HIS B CE1 1 ATOM 7844 N NE2 . HIS B 1 497 ? 36.063 42.299 -5.360 1.00 8.74 ? 497 HIS B NE2 1 ATOM 7845 N N . PRO B 1 498 ? 40.858 37.774 -6.789 1.00 7.21 ? 498 PRO B N 1 ATOM 7846 C CA . PRO B 1 498 ? 42.085 36.996 -6.968 1.00 6.24 ? 498 PRO B CA 1 ATOM 7847 C C . PRO B 1 498 ? 43.483 37.552 -6.732 1.00 7.35 ? 498 PRO B C 1 ATOM 7848 O O . PRO B 1 498 ? 44.434 36.769 -6.712 1.00 7.42 ? 498 PRO B O 1 ATOM 7849 C CB . PRO B 1 498 ? 41.943 36.514 -8.400 1.00 6.94 ? 498 PRO B CB 1 ATOM 7850 C CG . PRO B 1 498 ? 41.468 37.779 -9.067 1.00 6.75 ? 498 PRO B CG 1 ATOM 7851 C CD . PRO B 1 498 ? 40.398 38.296 -8.093 1.00 6.69 ? 498 PRO B CD 1 ATOM 7852 N N . GLN B 1 499 ? 43.645 38.858 -6.559 1.00 6.72 ? 499 GLN B N 1 ATOM 7853 C CA . GLN B 1 499 ? 45.004 39.364 -6.395 1.00 5.70 ? 499 GLN B CA 1 ATOM 7854 C C . GLN B 1 499 ? 45.735 38.741 -5.205 1.00 6.34 ? 499 GLN B C 1 ATOM 7855 O O . GLN B 1 499 ? 46.921 38.439 -5.300 1.00 6.33 ? 499 GLN B O 1 ATOM 7856 C CB . GLN B 1 499 ? 45.027 40.905 -6.321 1.00 6.99 ? 499 GLN B CB 1 ATOM 7857 C CG . GLN B 1 499 ? 44.852 41.537 -4.945 1.00 7.31 ? 499 GLN B CG 1 ATOM 7858 C CD . GLN B 1 499 ? 45.147 43.036 -4.970 1.00 6.92 ? 499 GLN B CD 1 ATOM 7859 O OE1 . GLN B 1 499 ? 46.090 43.479 -5.625 1.00 8.81 ? 499 GLN B OE1 1 ATOM 7860 N NE2 . GLN B 1 499 ? 44.351 43.815 -4.241 1.00 8.35 ? 499 GLN B NE2 1 ATOM 7861 N N . GLY B 1 500 ? 45.033 38.527 -4.096 1.00 5.77 ? 500 GLY B N 1 ATOM 7862 C CA . GLY B 1 500 ? 45.682 37.922 -2.943 1.00 6.95 ? 500 GLY B CA 1 ATOM 7863 C C . GLY B 1 500 ? 46.327 36.585 -3.288 1.00 7.10 ? 500 GLY B C 1 ATOM 7864 O O . GLY B 1 500 ? 47.474 36.314 -2.916 1.00 6.85 ? 500 GLY B O 1 ATOM 7865 N N . PHE B 1 501 ? 45.595 35.747 -4.013 1.00 7.18 ? 501 PHE B N 1 ATOM 7866 C CA . PHE B 1 501 ? 46.102 34.436 -4.405 1.00 6.91 ? 501 PHE B CA 1 ATOM 7867 C C . PHE B 1 501 ? 47.275 34.539 -5.384 1.00 6.04 ? 501 PHE B C 1 ATOM 7868 O O . PHE B 1 501 ? 48.262 33.818 -5.250 1.00 7.68 ? 501 PHE B O 1 ATOM 7869 C CB . PHE B 1 501 ? 44.978 33.606 -5.034 1.00 7.38 ? 501 PHE B CB 1 ATOM 7870 C CG . PHE B 1 501 ? 45.422 32.251 -5.522 1.00 8.35 ? 501 PHE B CG 1 ATOM 7871 C CD1 . PHE B 1 501 ? 45.666 31.216 -4.627 1.00 8.46 ? 501 PHE B CD1 1 ATOM 7872 C CD2 . PHE B 1 501 ? 45.613 32.020 -6.881 1.00 7.93 ? 501 PHE B CD2 1 ATOM 7873 C CE1 . PHE B 1 501 ? 46.094 29.969 -5.078 1.00 10.13 ? 501 PHE B CE1 1 ATOM 7874 C CE2 . PHE B 1 501 ? 46.042 30.778 -7.345 1.00 7.97 ? 501 PHE B CE2 1 ATOM 7875 C CZ . PHE B 1 501 ? 46.284 29.750 -6.440 1.00 9.17 ? 501 PHE B CZ 1 ATOM 7876 N N . TYR B 1 502 ? 47.174 35.438 -6.360 1.00 7.66 ? 502 TYR B N 1 ATOM 7877 C CA . TYR B 1 502 ? 48.241 35.594 -7.349 1.00 6.74 ? 502 TYR B CA 1 ATOM 7878 C C . TYR B 1 502 ? 49.502 36.208 -6.740 1.00 8.11 ? 502 TYR B C 1 ATOM 7879 O O . TYR B 1 502 ? 50.615 35.871 -7.147 1.00 8.82 ? 502 TYR B O 1 ATOM 7880 C CB . TYR B 1 502 ? 47.752 36.433 -8.539 1.00 7.65 ? 502 TYR B CB 1 ATOM 7881 C CG . TYR B 1 502 ? 46.577 35.820 -9.286 1.00 7.71 ? 502 TYR B CG 1 ATOM 7882 C CD1 . TYR B 1 502 ? 45.664 36.624 -9.967 1.00 7.42 ? 502 TYR B CD1 1 ATOM 7883 C CD2 . TYR B 1 502 ? 46.360 34.440 -9.285 1.00 6.96 ? 502 TYR B CD2 1 ATOM 7884 C CE1 . TYR B 1 502 ? 44.559 36.072 -10.622 1.00 8.11 ? 502 TYR B CE1 1 ATOM 7885 C CE2 . TYR B 1 502 ? 45.258 33.878 -9.937 1.00 6.63 ? 502 TYR B CE2 1 ATOM 7886 C CZ . TYR B 1 502 ? 44.361 34.700 -10.598 1.00 7.44 ? 502 TYR B CZ 1 ATOM 7887 O OH . TYR B 1 502 ? 43.247 34.159 -11.200 1.00 11.52 ? 502 TYR B OH 1 ATOM 7888 N N . LEU B 1 503 ? 49.331 37.102 -5.767 1.00 7.05 ? 503 LEU B N 1 ATOM 7889 C CA . LEU B 1 503 ? 50.477 37.719 -5.097 1.00 7.38 ? 503 LEU B CA 1 ATOM 7890 C C . LEU B 1 503 ? 51.213 36.612 -4.344 1.00 7.47 ? 503 LEU B C 1 ATOM 7891 O O . LEU B 1 503 ? 52.436 36.495 -4.422 1.00 8.08 ? 503 LEU B O 1 ATOM 7892 C CB . LEU B 1 503 ? 50.011 38.799 -4.112 1.00 7.66 ? 503 LEU B CB 1 ATOM 7893 C CG . LEU B 1 503 ? 49.463 40.105 -4.703 1.00 7.19 ? 503 LEU B CG 1 ATOM 7894 C CD1 . LEU B 1 503 ? 48.637 40.847 -3.662 1.00 8.69 ? 503 LEU B CD1 1 ATOM 7895 C CD2 . LEU B 1 503 ? 50.617 40.970 -5.199 1.00 8.09 ? 503 LEU B CD2 1 ATOM 7896 N N . MET B 1 504 ? 50.446 35.801 -3.621 1.00 7.55 ? 504 MET B N 1 ATOM 7897 C CA . MET B 1 504 ? 50.987 34.685 -2.853 1.00 7.52 ? 504 MET B CA 1 ATOM 7898 C C . MET B 1 504 ? 51.669 33.668 -3.771 1.00 8.62 ? 504 MET B C 1 ATOM 7899 O O . MET B 1 504 ? 52.764 33.188 -3.478 1.00 8.03 ? 504 MET B O 1 ATOM 7900 C CB . MET B 1 504 ? 49.850 34.016 -2.060 1.00 7.75 ? 504 MET B CB 1 ATOM 7901 C CG . MET B 1 504 ? 50.246 32.801 -1.224 1.00 7.02 ? 504 MET B CG 1 ATOM 7902 S SD . MET B 1 504 ? 50.434 31.259 -2.153 1.00 10.26 ? 504 MET B SD 1 ATOM 7903 C CE . MET B 1 504 ? 48.740 30.972 -2.683 1.00 10.56 ? 504 MET B CE 1 ATOM 7904 N N . LEU B 1 505 ? 51.029 33.356 -4.892 1.00 6.93 ? 505 LEU B N 1 ATOM 7905 C CA . LEU B 1 505 ? 51.568 32.385 -5.836 1.00 8.59 ? 505 LEU B CA 1 ATOM 7906 C C . LEU B 1 505 ? 52.991 32.707 -6.288 1.00 8.08 ? 505 LEU B C 1 ATOM 7907 O O . LEU B 1 505 ? 53.837 31.815 -6.391 1.00 7.70 ? 505 LEU B O 1 ATOM 7908 C CB . LEU B 1 505 ? 50.657 32.293 -7.063 1.00 8.25 ? 505 LEU B CB 1 ATOM 7909 C CG . LEU B 1 505 ? 51.049 31.244 -8.101 1.00 10.02 ? 505 LEU B CG 1 ATOM 7910 C CD1 . LEU B 1 505 ? 50.927 29.856 -7.486 1.00 10.98 ? 505 LEU B CD1 1 ATOM 7911 C CD2 . LEU B 1 505 ? 50.153 31.372 -9.319 1.00 12.73 ? 505 LEU B CD2 1 ATOM 7912 N N . GLY B 1 506 ? 53.247 33.983 -6.557 1.00 7.82 ? 506 GLY B N 1 ATOM 7913 C CA . GLY B 1 506 ? 54.564 34.393 -7.009 1.00 7.08 ? 506 GLY B CA 1 ATOM 7914 C C . GLY B 1 506 ? 55.654 33.989 -6.039 1.00 8.20 ? 506 GLY B C 1 ATOM 7915 O O . GLY B 1 506 ? 56.644 33.363 -6.429 1.00 8.10 ? 506 GLY B O 1 ATOM 7916 N N . ARG B 1 507 ? 55.489 34.349 -4.770 1.00 8.40 ? 507 ARG B N 1 ATOM 7917 C CA . ARG B 1 507 ? 56.500 33.986 -3.782 1.00 8.84 ? 507 ARG B CA 1 ATOM 7918 C C . ARG B 1 507 ? 56.476 32.489 -3.498 1.00 9.76 ? 507 ARG B C 1 ATOM 7919 O O . ARG B 1 507 ? 57.528 31.873 -3.317 1.00 10.25 ? 507 ARG B O 1 ATOM 7920 C CB . ARG B 1 507 ? 56.304 34.757 -2.473 1.00 10.11 ? 507 ARG B CB 1 ATOM 7921 C CG . ARG B 1 507 ? 57.222 34.261 -1.349 1.00 10.63 ? 507 ARG B CG 1 ATOM 7922 C CD . ARG B 1 507 ? 57.227 35.221 -0.177 1.00 12.19 ? 507 ARG B CD 1 ATOM 7923 N NE . ARG B 1 507 ? 58.016 34.746 0.962 1.00 9.57 ? 507 ARG B NE 1 ATOM 7924 C CZ . ARG B 1 507 ? 59.340 34.826 1.065 1.00 10.81 ? 507 ARG B CZ 1 ATOM 7925 N NH1 . ARG B 1 507 ? 60.066 35.363 0.093 1.00 10.57 ? 507 ARG B NH1 1 ATOM 7926 N NH2 . ARG B 1 507 ? 59.940 34.386 2.166 1.00 11.43 ? 507 ARG B NH2 1 ATOM 7927 N N . TYR B 1 508 ? 55.282 31.903 -3.459 1.00 9.75 ? 508 TYR B N 1 ATOM 7928 C CA . TYR B 1 508 ? 55.163 30.471 -3.193 1.00 9.38 ? 508 TYR B CA 1 ATOM 7929 C C . TYR B 1 508 ? 56.065 29.672 -4.133 1.00 9.87 ? 508 TYR B C 1 ATOM 7930 O O . TYR B 1 508 ? 56.887 28.868 -3.688 1.00 9.35 ? 508 TYR B O 1 ATOM 7931 C CB . TYR B 1 508 ? 53.712 30.005 -3.364 1.00 8.57 ? 508 TYR B CB 1 ATOM 7932 C CG . TYR B 1 508 ? 53.515 28.535 -3.057 1.00 8.82 ? 508 TYR B CG 1 ATOM 7933 C CD1 . TYR B 1 508 ? 53.301 28.097 -1.750 1.00 9.07 ? 508 TYR B CD1 1 ATOM 7934 C CD2 . TYR B 1 508 ? 53.590 27.580 -4.069 1.00 8.21 ? 508 TYR B CD2 1 ATOM 7935 C CE1 . TYR B 1 508 ? 53.169 26.739 -1.459 1.00 9.70 ? 508 TYR B CE1 1 ATOM 7936 C CE2 . TYR B 1 508 ? 53.460 26.223 -3.789 1.00 8.79 ? 508 TYR B CE2 1 ATOM 7937 C CZ . TYR B 1 508 ? 53.252 25.812 -2.482 1.00 9.85 ? 508 TYR B CZ 1 ATOM 7938 O OH . TYR B 1 508 ? 53.141 24.470 -2.197 1.00 11.30 ? 508 TYR B OH 1 ATOM 7939 N N . VAL B 1 509 ? 55.918 29.900 -5.435 1.00 8.92 ? 509 VAL B N 1 ATOM 7940 C CA . VAL B 1 509 ? 56.729 29.183 -6.414 1.00 8.96 ? 509 VAL B CA 1 ATOM 7941 C C . VAL B 1 509 ? 58.201 29.552 -6.269 1.00 10.40 ? 509 VAL B C 1 ATOM 7942 O O . VAL B 1 509 ? 59.083 28.718 -6.477 1.00 10.89 ? 509 VAL B O 1 ATOM 7943 C CB . VAL B 1 509 ? 56.246 29.470 -7.853 1.00 9.89 ? 509 VAL B CB 1 ATOM 7944 C CG1 . VAL B 1 509 ? 57.087 28.692 -8.856 1.00 10.55 ? 509 VAL B CG1 1 ATOM 7945 C CG2 . VAL B 1 509 ? 54.779 29.075 -7.985 1.00 11.50 ? 509 VAL B CG2 1 ATOM 7946 N N . GLY B 1 510 ? 58.470 30.799 -5.906 1.00 9.18 ? 510 GLY B N 1 ATOM 7947 C CA . GLY B 1 510 ? 59.847 31.216 -5.721 1.00 9.45 ? 510 GLY B CA 1 ATOM 7948 C C . GLY B 1 510 ? 60.519 30.389 -4.639 1.00 10.07 ? 510 GLY B C 1 ATOM 7949 O O . GLY B 1 510 ? 61.671 29.982 -4.789 1.00 12.59 ? 510 GLY B O 1 ATOM 7950 N N . ILE B 1 511 ? 59.802 30.144 -3.544 1.00 10.75 ? 511 ILE B N 1 ATOM 7951 C CA . ILE B 1 511 ? 60.336 29.354 -2.437 1.00 10.14 ? 511 ILE B CA 1 ATOM 7952 C C . ILE B 1 511 ? 60.511 27.898 -2.862 1.00 11.95 ? 511 ILE B C 1 ATOM 7953 O O . ILE B 1 511 ? 61.487 27.254 -2.489 1.00 12.56 ? 511 ILE B O 1 ATOM 7954 C CB . ILE B 1 511 ? 59.406 29.430 -1.195 1.00 10.81 ? 511 ILE B CB 1 ATOM 7955 C CG1 . ILE B 1 511 ? 59.444 30.843 -0.605 1.00 10.93 ? 511 ILE B CG1 1 ATOM 7956 C CG2 . ILE B 1 511 ? 59.831 28.405 -0.150 1.00 11.91 ? 511 ILE B CG2 1 ATOM 7957 C CD1 . ILE B 1 511 ? 60.820 31.280 -0.099 1.00 12.79 ? 511 ILE B CD1 1 ATOM 7958 N N . LYS B 1 512 ? 59.573 27.380 -3.646 1.00 12.38 ? 512 LYS B N 1 ATOM 7959 C CA . LYS B 1 512 ? 59.676 26.000 -4.116 1.00 13.86 ? 512 LYS B CA 1 ATOM 7960 C C . LYS B 1 512 ? 60.919 25.833 -4.985 1.00 13.47 ? 512 LYS B C 1 ATOM 7961 O O . LYS B 1 512 ? 61.573 24.796 -4.951 1.00 15.46 ? 512 LYS B O 1 ATOM 7962 C CB . LYS B 1 512 ? 58.430 25.603 -4.914 1.00 14.29 ? 512 LYS B CB 1 ATOM 7963 C CG . LYS B 1 512 ? 57.132 25.675 -4.119 1.00 17.16 ? 512 LYS B CG 1 ATOM 7964 C CD . LYS B 1 512 ? 57.069 24.640 -2.998 1.00 20.71 ? 512 LYS B CD 1 ATOM 7965 C CE . LYS B 1 512 ? 56.825 23.240 -3.544 1.00 22.79 ? 512 LYS B CE 1 ATOM 7966 N NZ . LYS B 1 512 ? 56.562 22.258 -2.454 1.00 24.85 ? 512 LYS B NZ 1 ATOM 7967 N N . ILE B 1 513 ? 61.241 26.861 -5.762 1.00 13.08 ? 513 ILE B N 1 ATOM 7968 C CA . ILE B 1 513 ? 62.417 26.824 -6.627 1.00 13.13 ? 513 ILE B CA 1 ATOM 7969 C C . ILE B 1 513 ? 63.681 26.886 -5.770 1.00 13.91 ? 513 ILE B C 1 ATOM 7970 O O . ILE B 1 513 ? 64.664 26.195 -6.045 1.00 14.82 ? 513 ILE B O 1 ATOM 7971 C CB . ILE B 1 513 ? 62.417 28.006 -7.643 1.00 11.91 ? 513 ILE B CB 1 ATOM 7972 C CG1 . ILE B 1 513 ? 61.316 27.791 -8.685 1.00 13.06 ? 513 ILE B CG1 1 ATOM 7973 C CG2 . ILE B 1 513 ? 63.789 28.130 -8.310 1.00 11.99 ? 513 ILE B CG2 1 ATOM 7974 C CD1 . ILE B 1 513 ? 61.116 28.972 -9.609 1.00 12.75 ? 513 ILE B CD1 1 ATOM 7975 N N . LEU B 1 514 ? 63.653 27.709 -4.727 1.00 14.01 ? 514 LEU B N 1 ATOM 7976 C CA . LEU B 1 514 ? 64.806 27.832 -3.837 1.00 15.18 ? 514 LEU B CA 1 ATOM 7977 C C . LEU B 1 514 ? 65.046 26.533 -3.081 1.00 16.87 ? 514 LEU B C 1 ATOM 7978 O O . LEU B 1 514 ? 66.191 26.135 -2.865 1.00 17.74 ? 514 LEU B O 1 ATOM 7979 C CB . LEU B 1 514 ? 64.609 28.981 -2.842 1.00 14.12 ? 514 LEU B CB 1 ATOM 7980 C CG . LEU B 1 514 ? 64.668 30.398 -3.422 1.00 13.86 ? 514 LEU B CG 1 ATOM 7981 C CD1 . LEU B 1 514 ? 64.547 31.407 -2.297 1.00 14.90 ? 514 LEU B CD1 1 ATOM 7982 C CD2 . LEU B 1 514 ? 65.980 30.599 -4.179 1.00 12.59 ? 514 LEU B CD2 1 ATOM 7983 N N . GLN B 1 515 ? 63.966 25.871 -2.679 1.00 16.33 ? 515 GLN B N 1 ATOM 7984 C CA . GLN B 1 515 ? 64.093 24.609 -1.961 1.00 18.12 ? 515 GLN B CA 1 ATOM 7985 C C . GLN B 1 515 ? 64.642 23.556 -2.914 1.00 18.72 ? 515 GLN B C 1 ATOM 7986 O O . GLN B 1 515 ? 65.396 22.669 -2.519 1.00 20.05 ? 515 GLN B O 1 ATOM 7987 C CB . GLN B 1 515 ? 62.738 24.162 -1.410 1.00 17.45 ? 515 GLN B CB 1 ATOM 7988 C CG . GLN B 1 515 ? 62.088 25.176 -0.481 1.00 17.71 ? 515 GLN B CG 1 ATOM 7989 C CD . GLN B 1 515 ? 60.829 24.649 0.183 1.00 19.63 ? 515 GLN B CD 1 ATOM 7990 O OE1 . GLN B 1 515 ? 60.049 23.918 -0.427 1.00 20.42 ? 515 GLN B OE1 1 ATOM 7991 N NE2 . GLN B 1 515 ? 60.617 25.035 1.434 1.00 21.31 ? 515 GLN B NE2 1 ATOM 7992 N N . GLU B 1 516 ? 64.259 23.669 -4.179 1.00 18.65 ? 516 GLU B N 1 ATOM 7993 C CA . GLU B 1 516 ? 64.723 22.735 -5.194 1.00 20.30 ? 516 GLU B CA 1 ATOM 7994 C C . GLU B 1 516 ? 66.221 22.939 -5.414 1.00 20.16 ? 516 GLU B C 1 ATOM 7995 O O . GLU B 1 516 ? 66.976 21.974 -5.510 1.00 21.03 ? 516 GLU B O 1 ATOM 7996 C CB . GLU B 1 516 ? 63.948 22.956 -6.497 1.00 21.32 ? 516 GLU B CB 1 ATOM 7997 C CG . GLU B 1 516 ? 64.130 21.857 -7.526 1.00 25.42 ? 516 GLU B CG 1 ATOM 7998 C CD . GLU B 1 516 ? 63.172 21.988 -8.688 1.00 27.73 ? 516 GLU B CD 1 ATOM 7999 O OE1 . GLU B 1 516 ? 63.288 22.968 -9.451 1.00 29.71 ? 516 GLU B OE1 1 ATOM 8000 O OE2 . GLU B 1 516 ? 62.299 21.107 -8.834 1.00 29.55 ? 516 GLU B OE2 1 ATOM 8001 N N . ARG B 1 517 ? 66.651 24.196 -5.483 1.00 19.28 ? 517 ARG B N 1 ATOM 8002 C CA . ARG B 1 517 ? 68.068 24.501 -5.675 1.00 19.72 ? 517 ARG B CA 1 ATOM 8003 C C . ARG B 1 517 ? 68.877 24.043 -4.463 1.00 20.89 ? 517 ARG B C 1 ATOM 8004 O O . ARG B 1 517 ? 69.999 23.557 -4.596 1.00 20.90 ? 517 ARG B O 1 ATOM 8005 C CB . ARG B 1 517 ? 68.279 26.011 -5.900 1.00 18.44 ? 517 ARG B CB 1 ATOM 8006 C CG . ARG B 1 517 ? 67.852 26.527 -7.268 1.00 17.56 ? 517 ARG B CG 1 ATOM 8007 C CD . ARG B 1 517 ? 68.630 25.861 -8.405 1.00 19.90 ? 517 ARG B CD 1 ATOM 8008 N NE . ARG B 1 517 ? 70.058 26.197 -8.447 1.00 17.64 ? 517 ARG B NE 1 ATOM 8009 C CZ . ARG B 1 517 ? 70.582 27.251 -9.070 1.00 17.93 ? 517 ARG B CZ 1 ATOM 8010 N NH1 . ARG B 1 517 ? 69.801 28.101 -9.719 1.00 17.96 ? 517 ARG B NH1 1 ATOM 8011 N NH2 . ARG B 1 517 ? 71.897 27.443 -9.065 1.00 18.33 ? 517 ARG B NH2 1 ATOM 8012 N N . SER B 1 518 ? 68.301 24.195 -3.278 1.00 21.16 ? 518 SER B N 1 ATOM 8013 C CA . SER B 1 518 ? 68.985 23.783 -2.061 1.00 23.70 ? 518 SER B CA 1 ATOM 8014 C C . SER B 1 518 ? 69.263 22.286 -2.083 1.00 24.59 ? 518 SER B C 1 ATOM 8015 O O . SER B 1 518 ? 70.362 21.840 -1.742 1.00 25.39 ? 518 SER B O 1 ATOM 8016 C CB . SER B 1 518 ? 68.139 24.115 -0.828 1.00 24.29 ? 518 SER B CB 1 ATOM 8017 O OG . SER B 1 518 ? 68.029 25.513 -0.654 1.00 28.33 ? 518 SER B OG 1 ATOM 8018 N N . ALA B 1 519 ? 68.260 21.517 -2.487 1.00 24.98 ? 519 ALA B N 1 ATOM 8019 C CA . ALA B 1 519 ? 68.381 20.069 -2.552 1.00 26.11 ? 519 ALA B CA 1 ATOM 8020 C C . ALA B 1 519 ? 69.388 19.617 -3.603 1.00 27.56 ? 519 ALA B C 1 ATOM 8021 O O . ALA B 1 519 ? 70.037 18.588 -3.437 1.00 28.41 ? 519 ALA B O 1 ATOM 8022 C CB . ALA B 1 519 ? 67.022 19.455 -2.836 1.00 25.33 ? 519 ALA B CB 1 ATOM 8023 N N . SER B 1 520 ? 69.526 20.386 -4.679 1.00 28.87 ? 520 SER B N 1 ATOM 8024 C CA . SER B 1 520 ? 70.454 20.016 -5.745 1.00 29.87 ? 520 SER B CA 1 ATOM 8025 C C . SER B 1 520 ? 71.877 20.523 -5.524 1.00 30.51 ? 520 SER B C 1 ATOM 8026 O O . SER B 1 520 ? 72.776 20.199 -6.297 1.00 30.66 ? 520 SER B O 1 ATOM 8027 C CB . SER B 1 520 ? 69.938 20.511 -7.103 1.00 30.03 ? 520 SER B CB 1 ATOM 8028 O OG . SER B 1 520 ? 70.152 21.898 -7.258 1.00 29.72 ? 520 SER B OG 1 ATOM 8029 N N . ASP B 1 521 ? 72.087 21.324 -4.482 1.00 31.75 ? 521 ASP B N 1 ATOM 8030 C CA . ASP B 1 521 ? 73.426 21.837 -4.205 1.00 33.20 ? 521 ASP B CA 1 ATOM 8031 C C . ASP B 1 521 ? 74.346 20.716 -3.743 1.00 33.71 ? 521 ASP B C 1 ATOM 8032 O O . ASP B 1 521 ? 75.555 20.983 -3.579 1.00 34.92 ? 521 ASP B O 1 ATOM 8033 C CB . ASP B 1 521 ? 73.402 22.934 -3.130 1.00 33.74 ? 521 ASP B CB 1 ATOM 8034 C CG . ASP B 1 521 ? 72.840 24.241 -3.639 1.00 34.87 ? 521 ASP B CG 1 ATOM 8035 O OD1 . ASP B 1 521 ? 73.105 24.587 -4.811 1.00 35.21 ? 521 ASP B OD1 1 ATOM 8036 O OD2 . ASP B 1 521 ? 72.146 24.928 -2.860 1.00 36.28 ? 521 ASP B OD2 1 ATOM 8037 O OXT . ASP B 1 521 ? 73.848 19.587 -3.548 1.00 33.47 ? 521 ASP B OXT 1 HETATM 8038 C C1 . IPA C 2 . ? 67.571 -18.031 -27.379 1.00 20.25 ? 522 IPA A C1 1 HETATM 8039 C C2 . IPA C 2 . ? 67.265 -19.130 -26.402 1.00 20.81 ? 522 IPA A C2 1 HETATM 8040 C C3 . IPA C 2 . ? 68.508 -19.994 -26.421 1.00 19.68 ? 522 IPA A C3 1 HETATM 8041 O O2 . IPA C 2 . ? 66.180 -20.010 -26.847 1.00 21.01 ? 522 IPA A O2 1 HETATM 8042 P PA . FAD D 3 . ? 74.194 -5.601 -33.116 1.00 6.03 ? 523 FAD A PA 1 HETATM 8043 O O1A . FAD D 3 . ? 74.306 -4.953 -31.779 1.00 9.18 ? 523 FAD A O1A 1 HETATM 8044 O O2A . FAD D 3 . ? 73.529 -4.915 -34.099 1.00 7.06 ? 523 FAD A O2A 1 HETATM 8045 O O5B . FAD D 3 . ? 75.654 -5.602 -33.512 1.00 7.80 ? 523 FAD A O5B 1 HETATM 8046 C C5B . FAD D 3 . ? 76.210 -5.941 -34.827 1.00 7.14 ? 523 FAD A C5B 1 HETATM 8047 C C4B . FAD D 3 . ? 77.280 -4.905 -35.120 1.00 6.27 ? 523 FAD A C4B 1 HETATM 8048 O O4B . FAD D 3 . ? 77.982 -5.316 -36.376 1.00 6.79 ? 523 FAD A O4B 1 HETATM 8049 C C3B . FAD D 3 . ? 76.778 -3.439 -35.400 1.00 7.82 ? 523 FAD A C3B 1 HETATM 8050 O O3B . FAD D 3 . ? 77.429 -2.501 -34.594 1.00 7.02 ? 523 FAD A O3B 1 HETATM 8051 C C2B . FAD D 3 . ? 77.009 -3.275 -36.939 1.00 6.41 ? 523 FAD A C2B 1 HETATM 8052 O O2B . FAD D 3 . ? 77.207 -1.929 -37.313 1.00 7.42 ? 523 FAD A O2B 1 HETATM 8053 C C1B . FAD D 3 . ? 78.231 -4.106 -37.165 1.00 6.44 ? 523 FAD A C1B 1 HETATM 8054 N N9A . FAD D 3 . ? 78.440 -4.655 -38.509 1.00 6.27 ? 523 FAD A N9A 1 HETATM 8055 C C8A . FAD D 3 . ? 77.511 -5.284 -39.323 1.00 5.18 ? 523 FAD A C8A 1 HETATM 8056 N N7A . FAD D 3 . ? 78.027 -5.684 -40.487 1.00 7.66 ? 523 FAD A N7A 1 HETATM 8057 C C5A . FAD D 3 . ? 79.346 -5.309 -40.424 1.00 5.05 ? 523 FAD A C5A 1 HETATM 8058 C C6A . FAD D 3 . ? 80.457 -5.450 -41.386 1.00 6.21 ? 523 FAD A C6A 1 HETATM 8059 N N6A . FAD D 3 . ? 80.332 -6.039 -42.544 1.00 9.13 ? 523 FAD A N6A 1 HETATM 8060 N N1A . FAD D 3 . ? 81.675 -4.928 -40.966 1.00 6.08 ? 523 FAD A N1A 1 HETATM 8061 C C2A . FAD D 3 . ? 81.836 -4.303 -39.747 1.00 6.76 ? 523 FAD A C2A 1 HETATM 8062 N N3A . FAD D 3 . ? 80.870 -4.128 -38.805 1.00 5.73 ? 523 FAD A N3A 1 HETATM 8063 C C4A . FAD D 3 . ? 79.642 -4.641 -39.195 1.00 6.15 ? 523 FAD A C4A 1 HETATM 8064 N N1 . FAD D 3 . ? 66.407 -5.179 -26.918 1.00 5.63 ? 523 FAD A N1 1 HETATM 8065 C C2 . FAD D 3 . ? 66.239 -5.087 -25.600 1.00 6.18 ? 523 FAD A C2 1 HETATM 8066 O O2 . FAD D 3 . ? 66.516 -5.988 -24.851 1.00 5.83 ? 523 FAD A O2 1 HETATM 8067 N N3 . FAD D 3 . ? 65.709 -3.901 -25.002 1.00 4.68 ? 523 FAD A N3 1 HETATM 8068 C C4 . FAD D 3 . ? 65.150 -2.876 -25.769 1.00 6.81 ? 523 FAD A C4 1 HETATM 8069 O O4 . FAD D 3 . ? 64.619 -1.941 -25.218 1.00 9.00 ? 523 FAD A O4 1 HETATM 8070 C C4X . FAD D 3 . ? 65.252 -3.003 -27.221 1.00 6.14 ? 523 FAD A C4X 1 HETATM 8071 N N5 . FAD D 3 . ? 64.704 -2.051 -28.049 1.00 7.26 ? 523 FAD A N5 1 HETATM 8072 C C5X . FAD D 3 . ? 65.097 -2.060 -29.379 1.00 6.33 ? 523 FAD A C5X 1 HETATM 8073 C C6 . FAD D 3 . ? 64.762 -0.918 -30.185 1.00 5.86 ? 523 FAD A C6 1 HETATM 8074 C C7 . FAD D 3 . ? 65.217 -0.807 -31.505 1.00 7.35 ? 523 FAD A C7 1 HETATM 8075 C C7M . FAD D 3 . ? 64.878 0.429 -32.316 1.00 9.30 ? 523 FAD A C7M 1 HETATM 8076 C C8 . FAD D 3 . ? 66.015 -1.898 -32.101 1.00 7.04 ? 523 FAD A C8 1 HETATM 8077 C C8M . FAD D 3 . ? 66.551 -1.844 -33.510 1.00 5.79 ? 523 FAD A C8M 1 HETATM 8078 C C9 . FAD D 3 . ? 66.298 -3.056 -31.330 1.00 6.08 ? 523 FAD A C9 1 HETATM 8079 C C9A . FAD D 3 . ? 65.879 -3.134 -29.973 1.00 5.51 ? 523 FAD A C9A 1 HETATM 8080 N N10 . FAD D 3 . ? 66.217 -4.248 -29.085 1.00 5.59 ? 523 FAD A N10 1 HETATM 8081 C C10 . FAD D 3 . ? 65.974 -4.179 -27.750 1.00 4.59 ? 523 FAD A C10 1 HETATM 8082 C "C1'" . FAD D 3 . ? 66.862 -5.460 -29.664 1.00 6.26 ? 523 FAD A "C1'" 1 HETATM 8083 C "C2'" . FAD D 3 . ? 68.372 -5.545 -29.286 1.00 6.35 ? 523 FAD A "C2'" 1 HETATM 8084 O "O2'" . FAD D 3 . ? 68.890 -4.206 -29.185 1.00 7.98 ? 523 FAD A "O2'" 1 HETATM 8085 C "C3'" . FAD D 3 . ? 69.085 -6.330 -30.385 1.00 6.58 ? 523 FAD A "C3'" 1 HETATM 8086 O "O3'" . FAD D 3 . ? 68.452 -7.611 -30.480 1.00 6.57 ? 523 FAD A "O3'" 1 HETATM 8087 C "C4'" . FAD D 3 . ? 70.570 -6.531 -30.030 1.00 6.94 ? 523 FAD A "C4'" 1 HETATM 8088 O "O4'" . FAD D 3 . ? 71.219 -5.275 -29.788 1.00 7.21 ? 523 FAD A "O4'" 1 HETATM 8089 C "C5'" . FAD D 3 . ? 71.218 -7.280 -31.175 1.00 6.59 ? 523 FAD A "C5'" 1 HETATM 8090 O "O5'" . FAD D 3 . ? 72.696 -7.614 -30.811 1.00 6.92 ? 523 FAD A "O5'" 1 HETATM 8091 P P . FAD D 3 . ? 73.669 -8.140 -31.865 1.00 6.67 ? 523 FAD A P 1 HETATM 8092 O O1P . FAD D 3 . ? 75.028 -8.188 -31.193 1.00 7.66 ? 523 FAD A O1P 1 HETATM 8093 O O2P . FAD D 3 . ? 73.218 -9.317 -32.477 1.00 7.99 ? 523 FAD A O2P 1 HETATM 8094 O O3P . FAD D 3 . ? 73.718 -7.167 -32.977 1.00 5.20 ? 523 FAD A O3P 1 HETATM 8095 C C1 . NAG E 4 . ? 59.783 -19.856 -20.507 1.00 16.33 ? 524 NAG A C1 1 HETATM 8096 C C2 . NAG E 4 . ? 58.330 -19.535 -20.881 1.00 17.67 ? 524 NAG A C2 1 HETATM 8097 C C3 . NAG E 4 . ? 57.482 -20.816 -20.857 1.00 20.00 ? 524 NAG A C3 1 HETATM 8098 C C4 . NAG E 4 . ? 58.144 -21.940 -21.668 1.00 20.59 ? 524 NAG A C4 1 HETATM 8099 C C5 . NAG E 4 . ? 59.602 -22.121 -21.237 1.00 19.73 ? 524 NAG A C5 1 HETATM 8100 C C6 . NAG E 4 . ? 60.343 -23.149 -22.073 1.00 19.20 ? 524 NAG A C6 1 HETATM 8101 C C7 . NAG E 4 . ? 57.508 -17.333 -20.302 1.00 16.99 ? 524 NAG A C7 1 HETATM 8102 C C8 . NAG E 4 . ? 56.767 -16.472 -19.292 1.00 17.20 ? 524 NAG A C8 1 HETATM 8103 N N2 . NAG E 4 . ? 57.792 -18.580 -19.931 1.00 17.74 ? 524 NAG A N2 1 HETATM 8104 O O3 . NAG E 4 . ? 56.197 -20.540 -21.394 1.00 21.89 ? 524 NAG A O3 1 HETATM 8105 O O4 . NAG E 4 . ? 57.435 -23.158 -21.468 1.00 22.62 ? 524 NAG A O4 1 HETATM 8106 O O5 . NAG E 4 . ? 60.311 -20.873 -21.368 1.00 17.45 ? 524 NAG A O5 1 HETATM 8107 O O6 . NAG E 4 . ? 60.507 -22.703 -23.411 1.00 21.04 ? 524 NAG A O6 1 HETATM 8108 O O7 . NAG E 4 . ? 57.810 -16.868 -21.400 1.00 15.19 ? 524 NAG A O7 1 HETATM 8109 C C1 . NAG F 4 . ? 70.825 -18.068 -11.894 1.00 16.58 ? 525 NAG A C1 1 HETATM 8110 C C2 . NAG F 4 . ? 70.572 -19.094 -10.778 1.00 20.09 ? 525 NAG A C2 1 HETATM 8111 C C3 . NAG F 4 . ? 69.074 -19.322 -10.524 1.00 23.90 ? 525 NAG A C3 1 HETATM 8112 C C4 . NAG F 4 . ? 68.336 -17.987 -10.376 1.00 22.22 ? 525 NAG A C4 1 HETATM 8113 C C5 . NAG F 4 . ? 68.633 -17.141 -11.610 1.00 19.34 ? 525 NAG A C5 1 HETATM 8114 C C6 . NAG F 4 . ? 67.931 -15.799 -11.618 1.00 16.36 ? 525 NAG A C6 1 HETATM 8115 C C7 . NAG F 4 . ? 72.389 -20.680 -10.645 1.00 21.41 ? 525 NAG A C7 1 HETATM 8116 C C8 . NAG F 4 . ? 73.015 -21.975 -11.140 1.00 20.80 ? 525 NAG A C8 1 HETATM 8117 N N2 . NAG F 4 . ? 71.196 -20.355 -11.137 1.00 21.09 ? 525 NAG A N2 1 HETATM 8118 O O3 . NAG F 4 . ? 68.913 -20.097 -9.320 1.00 29.56 ? 525 NAG A O3 1 HETATM 8119 O O4 . NAG F 4 . ? 66.914 -18.215 -10.254 1.00 25.61 ? 525 NAG A O4 1 HETATM 8120 O O5 . NAG F 4 . ? 70.049 -16.880 -11.682 1.00 16.77 ? 525 NAG A O5 1 HETATM 8121 O O6 . NAG F 4 . ? 68.219 -15.088 -12.813 1.00 14.20 ? 525 NAG A O6 1 HETATM 8122 O O7 . NAG F 4 . ? 72.987 -19.985 -9.823 1.00 23.23 ? 525 NAG A O7 1 HETATM 8123 C C1 . NAG G 4 . ? 66.270 -17.656 -9.152 1.00 31.10 ? 526 NAG A C1 1 HETATM 8124 C C2 . NAG G 4 . ? 64.758 -17.953 -9.240 1.00 32.68 ? 526 NAG A C2 1 HETATM 8125 C C3 . NAG G 4 . ? 64.033 -17.559 -7.935 1.00 35.84 ? 526 NAG A C3 1 HETATM 8126 C C4 . NAG G 4 . ? 64.738 -18.227 -6.743 1.00 38.47 ? 526 NAG A C4 1 HETATM 8127 C C5 . NAG G 4 . ? 66.201 -17.793 -6.742 1.00 37.18 ? 526 NAG A C5 1 HETATM 8128 C C6 . NAG G 4 . ? 66.973 -18.387 -5.577 1.00 38.03 ? 526 NAG A C6 1 HETATM 8129 C C7 . NAG G 4 . ? 64.187 -17.780 -11.584 1.00 30.27 ? 526 NAG A C7 1 HETATM 8130 C C8 . NAG G 4 . ? 64.085 -16.824 -12.762 1.00 30.14 ? 526 NAG A C8 1 HETATM 8131 N N2 . NAG G 4 . ? 64.172 -17.245 -10.365 1.00 30.67 ? 526 NAG A N2 1 HETATM 8132 O O3 . NAG G 4 . ? 62.679 -17.981 -7.999 1.00 36.39 ? 526 NAG A O3 1 HETATM 8133 O O4 . NAG G 4 . ? 64.112 -17.930 -5.464 1.00 43.25 ? 526 NAG A O4 1 HETATM 8134 O O5 . NAG G 4 . ? 66.838 -18.243 -7.962 1.00 33.90 ? 526 NAG A O5 1 HETATM 8135 O O6 . NAG G 4 . ? 68.294 -17.871 -5.517 1.00 39.95 ? 526 NAG A O6 1 HETATM 8136 O O7 . NAG G 4 . ? 64.282 -18.990 -11.787 1.00 30.28 ? 526 NAG A O7 1 HETATM 8137 C C1 . FUL H 5 . ? 67.934 -21.096 -9.357 1.00 35.50 ? 527 FUL A C1 1 HETATM 8138 C C2 . FUL H 5 . ? 67.786 -21.713 -7.962 1.00 38.35 ? 527 FUL A C2 1 HETATM 8139 O O2 . FUL H 5 . ? 67.422 -20.710 -7.027 1.00 39.07 ? 527 FUL A O2 1 HETATM 8140 C C3 . FUL H 5 . ? 66.720 -22.807 -7.983 1.00 39.74 ? 527 FUL A C3 1 HETATM 8141 O O3 . FUL H 5 . ? 66.650 -23.427 -6.708 1.00 41.43 ? 527 FUL A O3 1 HETATM 8142 C C4 . FUL H 5 . ? 67.065 -23.848 -9.049 1.00 40.34 ? 527 FUL A C4 1 HETATM 8143 O O4 . FUL H 5 . ? 68.271 -24.510 -8.694 1.00 41.43 ? 527 FUL A O4 1 HETATM 8144 C C5 . FUL H 5 . ? 67.237 -23.158 -10.408 1.00 40.25 ? 527 FUL A C5 1 HETATM 8145 C C6 . FUL H 5 . ? 67.694 -24.115 -11.493 1.00 40.46 ? 527 FUL A C6 1 HETATM 8146 O O5 . FUL H 5 . ? 68.233 -22.114 -10.311 1.00 37.79 ? 527 FUL A O5 1 HETATM 8147 C C1 . MAN I 6 . ? 63.688 -16.637 -5.178 1.00 46.60 ? 528 MAN A C1 1 HETATM 8148 C C2 . MAN I 6 . ? 63.899 -16.306 -3.686 1.00 47.90 ? 528 MAN A C2 1 HETATM 8149 C C3 . MAN I 6 . ? 62.934 -17.069 -2.758 1.00 48.90 ? 528 MAN A C3 1 HETATM 8150 C C4 . MAN I 6 . ? 61.494 -17.023 -3.278 1.00 49.69 ? 528 MAN A C4 1 HETATM 8151 C C5 . MAN I 6 . ? 61.472 -17.439 -4.748 1.00 49.76 ? 528 MAN A C5 1 HETATM 8152 C C6 . MAN I 6 . ? 60.093 -17.412 -5.376 1.00 50.90 ? 528 MAN A C6 1 HETATM 8153 O O2 . MAN I 6 . ? 63.737 -14.913 -3.479 1.00 48.23 ? 528 MAN A O2 1 HETATM 8154 O O3 . MAN I 6 . ? 62.978 -16.491 -1.461 1.00 49.84 ? 528 MAN A O3 1 HETATM 8155 O O4 . MAN I 6 . ? 60.680 -17.900 -2.514 1.00 49.85 ? 528 MAN A O4 1 HETATM 8156 O O5 . MAN I 6 . ? 62.304 -16.539 -5.517 1.00 48.47 ? 528 MAN A O5 1 HETATM 8157 O O6 . MAN I 6 . ? 60.121 -16.499 -6.490 1.00 52.26 ? 528 MAN A O6 1 HETATM 8158 C C1 . MAN J 6 . ? 58.919 -16.363 -7.186 1.00 52.66 ? 529 MAN A C1 1 HETATM 8159 C C2 . MAN J 6 . ? 59.010 -15.104 -8.053 1.00 52.63 ? 529 MAN A C2 1 HETATM 8160 C C3 . MAN J 6 . ? 59.008 -13.846 -7.168 1.00 53.02 ? 529 MAN A C3 1 HETATM 8161 C C4 . MAN J 6 . ? 57.808 -13.854 -6.213 1.00 53.23 ? 529 MAN A C4 1 HETATM 8162 C C5 . MAN J 6 . ? 57.786 -15.164 -5.419 1.00 53.27 ? 529 MAN A C5 1 HETATM 8163 C C6 . MAN J 6 . ? 56.567 -15.298 -4.527 1.00 53.26 ? 529 MAN A C6 1 HETATM 8164 O O2 . MAN J 6 . ? 57.923 -15.065 -8.960 1.00 52.72 ? 529 MAN A O2 1 HETATM 8165 O O3 . MAN J 6 . ? 58.968 -12.682 -7.980 1.00 52.82 ? 529 MAN A O3 1 HETATM 8166 O O4 . MAN J 6 . ? 57.901 -12.756 -5.318 1.00 53.42 ? 529 MAN A O4 1 HETATM 8167 O O5 . MAN J 6 . ? 57.782 -16.289 -6.325 1.00 52.77 ? 529 MAN A O5 1 HETATM 8168 O O6 . MAN J 6 . ? 55.908 -16.538 -4.736 1.00 53.29 ? 529 MAN A O6 1 HETATM 8169 C C1 . NAG K 4 . ? 53.854 -23.792 -36.823 1.00 24.46 ? 530 NAG A C1 1 HETATM 8170 C C2 . NAG K 4 . ? 53.993 -24.831 -37.940 1.00 27.79 ? 530 NAG A C2 1 HETATM 8171 C C3 . NAG K 4 . ? 53.713 -26.229 -37.384 1.00 31.60 ? 530 NAG A C3 1 HETATM 8172 C C4 . NAG K 4 . ? 54.638 -26.515 -36.199 1.00 32.14 ? 530 NAG A C4 1 HETATM 8173 C C5 . NAG K 4 . ? 54.483 -25.401 -35.153 1.00 29.75 ? 530 NAG A C5 1 HETATM 8174 C C6 . NAG K 4 . ? 55.433 -25.556 -33.979 1.00 30.04 ? 530 NAG A C6 1 HETATM 8175 C C7 . NAG K 4 . ? 53.543 -24.060 -40.175 1.00 29.15 ? 530 NAG A C7 1 HETATM 8176 C C8 . NAG K 4 . ? 52.574 -23.285 -41.052 1.00 29.06 ? 530 NAG A C8 1 HETATM 8177 N N2 . NAG K 4 . ? 53.077 -24.538 -39.026 1.00 28.69 ? 530 NAG A N2 1 HETATM 8178 O O3 . NAG K 4 . ? 53.918 -27.213 -38.415 1.00 35.24 ? 530 NAG A O3 1 HETATM 8179 O O4 . NAG K 4 . ? 54.298 -27.791 -35.616 1.00 36.37 ? 530 NAG A O4 1 HETATM 8180 O O5 . NAG K 4 . ? 54.754 -24.109 -35.750 1.00 25.61 ? 530 NAG A O5 1 HETATM 8181 O O6 . NAG K 4 . ? 56.787 -25.450 -34.395 1.00 30.59 ? 530 NAG A O6 1 HETATM 8182 O O7 . NAG K 4 . ? 54.709 -24.217 -40.539 1.00 30.92 ? 530 NAG A O7 1 HETATM 8183 C C1 . NAG L 4 . ? 55.353 -28.588 -35.186 1.00 40.36 ? 531 NAG A C1 1 HETATM 8184 C C2 . NAG L 4 . ? 54.820 -29.691 -34.262 1.00 41.29 ? 531 NAG A C2 1 HETATM 8185 C C3 . NAG L 4 . ? 55.949 -30.650 -33.875 1.00 42.67 ? 531 NAG A C3 1 HETATM 8186 C C4 . NAG L 4 . ? 56.647 -31.181 -35.128 1.00 42.85 ? 531 NAG A C4 1 HETATM 8187 C C5 . NAG L 4 . ? 57.110 -30.009 -35.997 1.00 43.01 ? 531 NAG A C5 1 HETATM 8188 C C6 . NAG L 4 . ? 57.753 -30.471 -37.293 1.00 43.17 ? 531 NAG A C6 1 HETATM 8189 C C7 . NAG L 4 . ? 52.927 -29.029 -32.929 1.00 42.23 ? 531 NAG A C7 1 HETATM 8190 C C8 . NAG L 4 . ? 52.396 -28.099 -31.851 1.00 42.86 ? 531 NAG A C8 1 HETATM 8191 N N2 . NAG L 4 . ? 54.246 -29.108 -33.065 1.00 41.66 ? 531 NAG A N2 1 HETATM 8192 O O3 . NAG L 4 . ? 55.418 -31.735 -33.127 1.00 43.55 ? 531 NAG A O3 1 HETATM 8193 O O4 . NAG L 4 . ? 57.765 -31.974 -34.754 1.00 43.75 ? 531 NAG A O4 1 HETATM 8194 O O5 . NAG L 4 . ? 55.980 -29.171 -36.342 1.00 41.81 ? 531 NAG A O5 1 HETATM 8195 O O6 . NAG L 4 . ? 57.150 -29.856 -38.422 1.00 44.37 ? 531 NAG A O6 1 HETATM 8196 O O7 . NAG L 4 . ? 52.141 -29.667 -33.632 1.00 42.80 ? 531 NAG A O7 1 HETATM 8197 C C1 . FUC M 7 . ? 52.755 -27.673 -39.050 1.00 39.07 ? 532 FUC A C1 1 HETATM 8198 C C2 . FUC M 7 . ? 53.131 -28.574 -40.232 1.00 40.64 ? 532 FUC A C2 1 HETATM 8199 C C3 . FUC M 7 . ? 53.748 -29.882 -39.724 1.00 41.79 ? 532 FUC A C3 1 HETATM 8200 C C4 . FUC M 7 . ? 52.800 -30.561 -38.732 1.00 41.98 ? 532 FUC A C4 1 HETATM 8201 C C5 . FUC M 7 . ? 52.440 -29.587 -37.605 1.00 41.57 ? 532 FUC A C5 1 HETATM 8202 C C6 . FUC M 7 . ? 51.411 -30.156 -36.648 1.00 41.50 ? 532 FUC A C6 1 HETATM 8203 O O2 . FUC M 7 . ? 54.056 -27.900 -41.073 1.00 41.49 ? 532 FUC A O2 1 HETATM 8204 O O3 . FUC M 7 . ? 53.999 -30.751 -40.818 1.00 43.35 ? 532 FUC A O3 1 HETATM 8205 O O4 . FUC M 7 . ? 51.617 -30.970 -39.404 1.00 42.12 ? 532 FUC A O4 1 HETATM 8206 O O5 . FUC M 7 . ? 51.885 -28.372 -38.158 1.00 40.42 ? 532 FUC A O5 1 HETATM 8207 C C1 . NAG N 4 . ? 45.657 16.487 -34.275 1.00 37.88 ? 533 NAG A C1 1 HETATM 8208 C C2 . NAG N 4 . ? 45.204 16.362 -35.743 1.00 40.12 ? 533 NAG A C2 1 HETATM 8209 C C3 . NAG N 4 . ? 43.685 16.167 -35.843 1.00 41.37 ? 533 NAG A C3 1 HETATM 8210 C C4 . NAG N 4 . ? 43.246 15.006 -34.956 1.00 41.31 ? 533 NAG A C4 1 HETATM 8211 C C5 . NAG N 4 . ? 43.733 15.256 -33.529 1.00 40.60 ? 533 NAG A C5 1 HETATM 8212 C C6 . NAG N 4 . ? 43.363 14.131 -32.584 1.00 39.44 ? 533 NAG A C6 1 HETATM 8213 C C7 . NAG N 4 . ? 46.183 17.424 -37.669 1.00 42.73 ? 533 NAG A C7 1 HETATM 8214 C C8 . NAG N 4 . ? 46.194 18.650 -38.567 1.00 42.63 ? 533 NAG A C8 1 HETATM 8215 N N2 . NAG N 4 . ? 45.595 17.546 -36.483 1.00 41.68 ? 533 NAG A N2 1 HETATM 8216 O O3 . NAG N 4 . ? 43.320 15.899 -37.191 1.00 42.73 ? 533 NAG A O3 1 HETATM 8217 O O4 . NAG N 4 . ? 41.829 14.894 -34.976 1.00 42.81 ? 533 NAG A O4 1 HETATM 8218 O O5 . NAG N 4 . ? 45.174 15.371 -33.510 1.00 38.90 ? 533 NAG A O5 1 HETATM 8219 O O6 . NAG N 4 . ? 43.641 14.486 -31.238 1.00 39.01 ? 533 NAG A O6 1 HETATM 8220 O O7 . NAG N 4 . ? 46.702 16.374 -38.054 1.00 43.02 ? 533 NAG A O7 1 HETATM 8221 C C1 . IPA O 2 . ? 42.679 28.925 -8.384 1.00 19.61 ? 522 IPA B C1 1 HETATM 8222 C C2 . IPA O 2 . ? 42.284 27.797 -7.475 1.00 21.76 ? 522 IPA B C2 1 HETATM 8223 C C3 . IPA O 2 . ? 43.470 26.858 -7.522 1.00 21.00 ? 522 IPA B C3 1 HETATM 8224 O O2 . IPA O 2 . ? 41.158 27.013 -7.990 1.00 20.21 ? 522 IPA B O2 1 HETATM 8225 P PA . FAD P 3 . ? 49.458 41.161 -14.251 1.00 7.10 ? 523 FAD B PA 1 HETATM 8226 O O1A . FAD P 3 . ? 49.594 41.839 -12.932 1.00 7.73 ? 523 FAD B O1A 1 HETATM 8227 O O2A . FAD P 3 . ? 48.783 41.826 -15.238 1.00 7.35 ? 523 FAD B O2A 1 HETATM 8228 O O5B . FAD P 3 . ? 50.910 41.142 -14.663 1.00 6.62 ? 523 FAD B O5B 1 HETATM 8229 C C5B . FAD P 3 . ? 51.441 40.784 -15.986 1.00 7.84 ? 523 FAD B C5B 1 HETATM 8230 C C4B . FAD P 3 . ? 52.527 41.792 -16.274 1.00 7.85 ? 523 FAD B C4B 1 HETATM 8231 O O4B . FAD P 3 . ? 53.214 41.365 -17.533 1.00 8.29 ? 523 FAD B O4B 1 HETATM 8232 C C3B . FAD P 3 . ? 52.051 43.266 -16.555 1.00 7.77 ? 523 FAD B C3B 1 HETATM 8233 O O3B . FAD P 3 . ? 52.690 44.203 -15.738 1.00 7.90 ? 523 FAD B O3B 1 HETATM 8234 C C2B . FAD P 3 . ? 52.309 43.432 -18.088 1.00 7.24 ? 523 FAD B C2B 1 HETATM 8235 O O2B . FAD P 3 . ? 52.547 44.777 -18.443 1.00 8.16 ? 523 FAD B O2B 1 HETATM 8236 C C1B . FAD P 3 . ? 53.514 42.571 -18.302 1.00 8.23 ? 523 FAD B C1B 1 HETATM 8237 N N9A . FAD P 3 . ? 53.727 42.025 -19.643 1.00 7.16 ? 523 FAD B N9A 1 HETATM 8238 C C8A . FAD P 3 . ? 52.789 41.426 -20.471 1.00 7.08 ? 523 FAD B C8A 1 HETATM 8239 N N7A . FAD P 3 . ? 53.301 41.020 -21.628 1.00 7.22 ? 523 FAD B N7A 1 HETATM 8240 C C5A . FAD P 3 . ? 54.633 41.366 -21.553 1.00 8.68 ? 523 FAD B C5A 1 HETATM 8241 C C6A . FAD P 3 . ? 55.751 41.195 -22.503 1.00 9.00 ? 523 FAD B C6A 1 HETATM 8242 N N6A . FAD P 3 . ? 55.621 40.623 -23.673 1.00 9.71 ? 523 FAD B N6A 1 HETATM 8243 N N1A . FAD P 3 . ? 56.976 41.685 -22.066 1.00 8.83 ? 523 FAD B N1A 1 HETATM 8244 C C2A . FAD P 3 . ? 57.146 42.290 -20.842 1.00 8.79 ? 523 FAD B C2A 1 HETATM 8245 N N3A . FAD P 3 . ? 56.175 42.486 -19.907 1.00 9.41 ? 523 FAD B N3A 1 HETATM 8246 C C4A . FAD P 3 . ? 54.938 42.008 -20.313 1.00 7.76 ? 523 FAD B C4A 1 HETATM 8247 N N1 . FAD P 3 . ? 41.634 41.627 -8.067 1.00 5.64 ? 523 FAD B N1 1 HETATM 8248 C C2 . FAD P 3 . ? 41.524 41.747 -6.738 1.00 6.92 ? 523 FAD B C2 1 HETATM 8249 O O2 . FAD P 3 . ? 41.872 40.879 -5.978 1.00 7.40 ? 523 FAD B O2 1 HETATM 8250 N N3 . FAD P 3 . ? 40.973 42.927 -6.139 1.00 5.84 ? 523 FAD B N3 1 HETATM 8251 C C4 . FAD P 3 . ? 40.441 43.968 -6.908 1.00 8.29 ? 523 FAD B C4 1 HETATM 8252 O O4 . FAD P 3 . ? 39.944 44.922 -6.349 1.00 7.65 ? 523 FAD B O4 1 HETATM 8253 C C4X . FAD P 3 . ? 40.527 43.835 -8.365 1.00 6.01 ? 523 FAD B C4X 1 HETATM 8254 N N5 . FAD P 3 . ? 39.982 44.790 -9.195 1.00 6.69 ? 523 FAD B N5 1 HETATM 8255 C C5X . FAD P 3 . ? 40.407 44.804 -10.517 1.00 6.98 ? 523 FAD B C5X 1 HETATM 8256 C C6 . FAD P 3 . ? 40.096 45.958 -11.319 1.00 6.92 ? 523 FAD B C6 1 HETATM 8257 C C7 . FAD P 3 . ? 40.540 46.064 -12.643 1.00 7.90 ? 523 FAD B C7 1 HETATM 8258 C C7M . FAD P 3 . ? 40.178 47.289 -13.463 1.00 7.25 ? 523 FAD B C7M 1 HETATM 8259 C C8 . FAD P 3 . ? 41.342 44.979 -13.238 1.00 7.34 ? 523 FAD B C8 1 HETATM 8260 C C8M . FAD P 3 . ? 41.868 45.035 -14.652 1.00 6.30 ? 523 FAD B C8M 1 HETATM 8261 C C9 . FAD P 3 . ? 41.628 43.822 -12.465 1.00 7.96 ? 523 FAD B C9 1 HETATM 8262 C C9A . FAD P 3 . ? 41.191 43.730 -11.115 1.00 6.39 ? 523 FAD B C9A 1 HETATM 8263 N N10 . FAD P 3 . ? 41.505 42.600 -10.233 1.00 6.25 ? 523 FAD B N10 1 HETATM 8264 C C10 . FAD P 3 . ? 41.235 42.650 -8.899 1.00 5.68 ? 523 FAD B C10 1 HETATM 8265 C "C1'" . FAD P 3 . ? 42.150 41.396 -10.823 1.00 6.03 ? 523 FAD B "C1'" 1 HETATM 8266 C "C2'" . FAD P 3 . ? 43.662 41.309 -10.454 1.00 7.27 ? 523 FAD B "C2'" 1 HETATM 8267 O "O2'" . FAD P 3 . ? 44.191 42.647 -10.379 1.00 7.18 ? 523 FAD B "O2'" 1 HETATM 8268 C "C3'" . FAD P 3 . ? 44.361 40.506 -11.546 1.00 6.08 ? 523 FAD B "C3'" 1 HETATM 8269 O "O3'" . FAD P 3 . ? 43.696 39.239 -11.659 1.00 6.85 ? 523 FAD B "O3'" 1 HETATM 8270 C "C4'" . FAD P 3 . ? 45.837 40.272 -11.176 1.00 7.25 ? 523 FAD B "C4'" 1 HETATM 8271 O "O4'" . FAD P 3 . ? 46.521 41.514 -10.968 1.00 6.24 ? 523 FAD B "O4'" 1 HETATM 8272 C "C5'" . FAD P 3 . ? 46.466 39.479 -12.291 1.00 5.87 ? 523 FAD B "C5'" 1 HETATM 8273 O "O5'" . FAD P 3 . ? 47.950 39.189 -11.932 1.00 7.59 ? 523 FAD B "O5'" 1 HETATM 8274 P P . FAD P 3 . ? 48.912 38.643 -12.975 1.00 6.55 ? 523 FAD B P 1 HETATM 8275 O O1P . FAD P 3 . ? 50.270 38.577 -12.301 1.00 7.09 ? 523 FAD B O1P 1 HETATM 8276 O O2P . FAD P 3 . ? 48.443 37.467 -13.562 1.00 7.16 ? 523 FAD B O2P 1 HETATM 8277 O O3P . FAD P 3 . ? 48.977 39.601 -14.089 1.00 6.72 ? 523 FAD B O3P 1 HETATM 8278 C C1 . NAG Q 4 . ? 29.673 18.348 -16.105 1.00 28.67 ? 524 NAG B C1 1 HETATM 8279 C C2 . NAG Q 4 . ? 29.034 17.327 -15.158 1.00 29.19 ? 524 NAG B C2 1 HETATM 8280 C C3 . NAG Q 4 . ? 30.034 16.224 -14.798 1.00 30.56 ? 524 NAG B C3 1 HETATM 8281 C C4 . NAG Q 4 . ? 30.691 15.638 -16.051 1.00 32.43 ? 524 NAG B C4 1 HETATM 8282 C C5 . NAG Q 4 . ? 31.263 16.763 -16.917 1.00 32.29 ? 524 NAG B C5 1 HETATM 8283 C C6 . NAG Q 4 . ? 31.874 16.264 -18.215 1.00 33.22 ? 524 NAG B C6 1 HETATM 8284 C C7 . NAG Q 4 . ? 27.316 18.083 -13.641 1.00 29.58 ? 524 NAG B C7 1 HETATM 8285 C C8 . NAG Q 4 . ? 26.970 18.458 -12.210 1.00 30.18 ? 524 NAG B C8 1 HETATM 8286 N N2 . NAG Q 4 . ? 28.607 18.000 -13.946 1.00 28.29 ? 524 NAG B N2 1 HETATM 8287 O O3 . NAG Q 4 . ? 29.362 15.194 -14.090 1.00 29.55 ? 524 NAG B O3 1 HETATM 8288 O O4 . NAG Q 4 . ? 31.753 14.750 -15.659 1.00 35.09 ? 524 NAG B O4 1 HETATM 8289 O O5 . NAG Q 4 . ? 30.218 17.694 -17.261 1.00 29.81 ? 524 NAG B O5 1 HETATM 8290 O O6 . NAG Q 4 . ? 31.017 16.507 -19.319 1.00 36.44 ? 524 NAG B O6 1 HETATM 8291 O O7 . NAG Q 4 . ? 26.418 17.871 -14.457 1.00 30.09 ? 524 NAG B O7 1 HETATM 8292 C C1 . NAG R 4 . ? 28.697 23.227 -17.796 1.00 18.92 ? 525 NAG B C1 1 HETATM 8293 C C2 . NAG R 4 . ? 28.784 22.183 -18.915 1.00 21.91 ? 525 NAG B C2 1 HETATM 8294 C C3 . NAG R 4 . ? 28.405 20.799 -18.376 1.00 24.27 ? 525 NAG B C3 1 HETATM 8295 C C4 . NAG R 4 . ? 29.203 20.469 -17.110 1.00 23.91 ? 525 NAG B C4 1 HETATM 8296 C C5 . NAG R 4 . ? 29.069 21.603 -16.091 1.00 22.16 ? 525 NAG B C5 1 HETATM 8297 C C6 . NAG R 4 . ? 29.899 21.383 -14.839 1.00 22.97 ? 525 NAG B C6 1 HETATM 8298 C C7 . NAG R 4 . ? 28.356 22.784 -21.215 1.00 22.89 ? 525 NAG B C7 1 HETATM 8299 C C8 . NAG R 4 . ? 27.337 23.098 -22.302 1.00 23.91 ? 525 NAG B C8 1 HETATM 8300 N N2 . NAG R 4 . ? 27.884 22.548 -19.995 1.00 22.79 ? 525 NAG B N2 1 HETATM 8301 O O3 . NAG R 4 . ? 28.669 19.803 -19.383 1.00 27.97 ? 525 NAG B O3 1 HETATM 8302 O O4 . NAG R 4 . ? 28.711 19.245 -16.534 1.00 25.76 ? 525 NAG B O4 1 HETATM 8303 O O5 . NAG R 4 . ? 29.508 22.839 -16.682 1.00 20.23 ? 525 NAG B O5 1 HETATM 8304 O O6 . NAG R 4 . ? 31.248 21.071 -15.160 1.00 25.94 ? 525 NAG B O6 1 HETATM 8305 O O7 . NAG R 4 . ? 29.557 22.755 -21.489 1.00 24.92 ? 525 NAG B O7 1 HETATM 8306 C C1 . FUC S 7 . ? 27.553 19.366 -20.108 1.00 31.66 ? 526 FUC B C1 1 HETATM 8307 C C2 . FUC S 7 . ? 28.004 18.487 -21.280 1.00 33.29 ? 526 FUC B C2 1 HETATM 8308 C C3 . FUC S 7 . ? 28.552 17.151 -20.767 1.00 34.48 ? 526 FUC B C3 1 HETATM 8309 C C4 . FUC S 7 . ? 27.526 16.471 -19.856 1.00 34.94 ? 526 FUC B C4 1 HETATM 8310 C C5 . FUC S 7 . ? 27.108 17.426 -18.734 1.00 34.44 ? 526 FUC B C5 1 HETATM 8311 C C6 . FUC S 7 . ? 26.004 16.855 -17.866 1.00 35.14 ? 526 FUC B C6 1 HETATM 8312 O O2 . FUC S 7 . ? 29.008 19.160 -22.025 1.00 33.35 ? 526 FUC B O2 1 HETATM 8313 O O3 . FUC S 7 . ? 28.850 16.302 -21.865 1.00 35.50 ? 526 FUC B O3 1 HETATM 8314 O O4 . FUC S 7 . ? 26.386 16.099 -20.617 1.00 36.11 ? 526 FUC B O4 1 HETATM 8315 O O5 . FUC S 7 . ? 26.613 18.663 -19.295 1.00 32.99 ? 526 FUC B O5 1 HETATM 8316 C C1 . BMA T 8 . ? 31.566 13.402 -15.915 1.00 38.16 ? 527 BMA B C1 1 HETATM 8317 C C2 . BMA T 8 . ? 32.900 12.672 -15.741 1.00 39.34 ? 527 BMA B C2 1 HETATM 8318 C C3 . BMA T 8 . ? 32.705 11.163 -15.883 1.00 40.82 ? 527 BMA B C3 1 HETATM 8319 C C4 . BMA T 8 . ? 31.605 10.676 -14.940 1.00 40.34 ? 527 BMA B C4 1 HETATM 8320 C C5 . BMA T 8 . ? 30.328 11.492 -15.158 1.00 39.97 ? 527 BMA B C5 1 HETATM 8321 C C6 . BMA T 8 . ? 29.229 11.119 -14.181 1.00 41.03 ? 527 BMA B C6 1 HETATM 8322 O O2 . BMA T 8 . ? 33.440 12.966 -14.461 1.00 40.33 ? 527 BMA B O2 1 HETATM 8323 O O3 . BMA T 8 . ? 33.938 10.495 -15.565 1.00 42.65 ? 527 BMA B O3 1 HETATM 8324 O O4 . BMA T 8 . ? 31.344 9.302 -15.182 1.00 41.10 ? 527 BMA B O4 1 HETATM 8325 O O5 . BMA T 8 . ? 30.600 12.900 -14.977 1.00 39.02 ? 527 BMA B O5 1 HETATM 8326 O O6 . BMA T 8 . ? 29.596 11.441 -12.847 1.00 40.90 ? 527 BMA B O6 1 HETATM 8327 C C1 . MAN U 6 . ? 34.414 9.609 -16.538 1.00 44.62 ? 528 MAN B C1 1 HETATM 8328 C C2 . MAN U 6 . ? 35.602 8.816 -15.974 1.00 44.81 ? 528 MAN B C2 1 HETATM 8329 C C3 . MAN U 6 . ? 36.826 9.725 -15.818 1.00 45.30 ? 528 MAN B C3 1 HETATM 8330 C C4 . MAN U 6 . ? 37.140 10.420 -17.144 1.00 45.47 ? 528 MAN B C4 1 HETATM 8331 C C5 . MAN U 6 . ? 35.902 11.178 -17.632 1.00 45.91 ? 528 MAN B C5 1 HETATM 8332 C C6 . MAN U 6 . ? 36.106 11.823 -18.989 1.00 46.46 ? 528 MAN B C6 1 HETATM 8333 O O2 . MAN U 6 . ? 35.913 7.736 -16.840 1.00 45.91 ? 528 MAN B O2 1 HETATM 8334 O O3 . MAN U 6 . ? 37.946 8.959 -15.402 1.00 43.64 ? 528 MAN B O3 1 HETATM 8335 O O4 . MAN U 6 . ? 38.221 11.324 -16.966 1.00 46.23 ? 528 MAN B O4 1 HETATM 8336 O O5 . MAN U 6 . ? 34.782 10.271 -17.752 1.00 45.20 ? 528 MAN B O5 1 HETATM 8337 O O6 . MAN U 6 . ? 36.597 10.885 -19.936 1.00 46.55 ? 528 MAN B O6 1 HETATM 8338 C C1 . NAG V 4 . ? 46.092 28.811 7.006 1.00 15.51 ? 529 NAG B C1 1 HETATM 8339 C C2 . NAG V 4 . ? 45.854 27.760 8.102 1.00 18.96 ? 529 NAG B C2 1 HETATM 8340 C C3 . NAG V 4 . ? 44.362 27.467 8.264 1.00 20.16 ? 529 NAG B C3 1 HETATM 8341 C C4 . NAG V 4 . ? 43.659 28.787 8.563 1.00 19.84 ? 529 NAG B C4 1 HETATM 8342 C C5 . NAG V 4 . ? 43.890 29.705 7.360 1.00 18.36 ? 529 NAG B C5 1 HETATM 8343 C C6 . NAG V 4 . ? 43.170 31.039 7.407 1.00 17.02 ? 529 NAG B C6 1 HETATM 8344 C C7 . NAG V 4 . ? 47.654 26.212 8.486 1.00 22.01 ? 529 NAG B C7 1 HETATM 8345 C C8 . NAG V 4 . ? 48.336 24.899 8.131 1.00 22.24 ? 529 NAG B C8 1 HETATM 8346 N N2 . NAG V 4 . ? 46.573 26.542 7.785 1.00 20.62 ? 529 NAG B N2 1 HETATM 8347 O O3 . NAG V 4 . ? 44.161 26.532 9.342 1.00 22.68 ? 529 NAG B O3 1 HETATM 8348 O O4 . NAG V 4 . ? 42.253 28.581 8.801 1.00 22.94 ? 529 NAG B O4 1 HETATM 8349 O O5 . NAG V 4 . ? 45.299 29.989 7.245 1.00 14.22 ? 529 NAG B O5 1 HETATM 8350 O O6 . NAG V 4 . ? 43.399 31.770 6.209 1.00 16.98 ? 529 NAG B O6 1 HETATM 8351 O O7 . NAG V 4 . ? 48.109 26.918 9.391 1.00 23.85 ? 529 NAG B O7 1 HETATM 8352 C C1 . NAG W 4 . ? 41.719 29.349 9.828 1.00 28.28 ? 530 NAG B C1 1 HETATM 8353 C C2 . NAG W 4 . ? 40.191 29.318 9.775 1.00 29.06 ? 530 NAG B C2 1 HETATM 8354 C C3 . NAG W 4 . ? 39.596 30.076 10.975 1.00 32.38 ? 530 NAG B C3 1 HETATM 8355 C C4 . NAG W 4 . ? 40.237 29.647 12.309 1.00 34.37 ? 530 NAG B C4 1 HETATM 8356 C C5 . NAG W 4 . ? 41.767 29.647 12.193 1.00 33.57 ? 530 NAG B C5 1 HETATM 8357 C C6 . NAG W 4 . ? 42.471 29.122 13.435 1.00 33.79 ? 530 NAG B C6 1 HETATM 8358 C C7 . NAG W 4 . ? 39.262 29.204 7.551 1.00 27.77 ? 530 NAG B C7 1 HETATM 8359 C C8 . NAG W 4 . ? 38.240 29.865 6.641 1.00 27.55 ? 530 NAG B C8 1 HETATM 8360 N N2 . NAG W 4 . ? 39.749 29.942 8.542 1.00 27.56 ? 530 NAG B N2 1 HETATM 8361 O O3 . NAG W 4 . ? 38.196 29.841 11.031 1.00 31.69 ? 530 NAG B O3 1 HETATM 8362 O O4 . NAG W 4 . ? 39.836 30.564 13.352 1.00 38.73 ? 530 NAG B O4 1 HETATM 8363 O O5 . NAG W 4 . ? 42.181 28.825 11.080 1.00 30.21 ? 530 NAG B O5 1 HETATM 8364 O O6 . NAG W 4 . ? 42.366 27.708 13.533 1.00 35.91 ? 530 NAG B O6 1 HETATM 8365 O O7 . NAG W 4 . ? 39.600 28.037 7.351 1.00 28.57 ? 530 NAG B O7 1 HETATM 8366 C C1 . BMA X 8 . ? 38.980 30.073 14.330 1.00 42.61 ? 531 BMA B C1 1 HETATM 8367 C C2 . BMA X 8 . ? 38.881 31.078 15.482 1.00 43.76 ? 531 BMA B C2 1 HETATM 8368 C C3 . BMA X 8 . ? 37.899 30.557 16.529 1.00 44.98 ? 531 BMA B C3 1 HETATM 8369 C C4 . BMA X 8 . ? 36.547 30.259 15.877 1.00 45.70 ? 531 BMA B C4 1 HETATM 8370 C C5 . BMA X 8 . ? 36.709 29.346 14.651 1.00 45.97 ? 531 BMA B C5 1 HETATM 8371 C C6 . BMA X 8 . ? 35.411 29.247 13.875 1.00 47.50 ? 531 BMA B C6 1 HETATM 8372 O O2 . BMA X 8 . ? 38.425 32.329 14.987 1.00 44.79 ? 531 BMA B O2 1 HETATM 8373 O O3 . BMA X 8 . ? 37.731 31.531 17.548 1.00 44.82 ? 531 BMA B O3 1 HETATM 8374 O O4 . BMA X 8 . ? 35.689 29.636 16.821 1.00 46.54 ? 531 BMA B O4 1 HETATM 8375 O O5 . BMA X 8 . ? 37.690 29.889 13.735 1.00 43.98 ? 531 BMA B O5 1 HETATM 8376 O O6 . BMA X 8 . ? 35.162 30.504 13.213 1.00 49.52 ? 531 BMA B O6 1 HETATM 8377 C C1 . MAN Y 6 . ? 34.226 30.396 12.181 1.00 50.44 ? 532 MAN B C1 1 HETATM 8378 C C2 . MAN Y 6 . ? 34.352 31.610 11.249 1.00 50.76 ? 532 MAN B C2 1 HETATM 8379 C C3 . MAN Y 6 . ? 33.862 32.884 11.951 1.00 51.18 ? 532 MAN B C3 1 HETATM 8380 C C4 . MAN Y 6 . ? 32.454 32.680 12.518 1.00 51.29 ? 532 MAN B C4 1 HETATM 8381 C C5 . MAN Y 6 . ? 32.424 31.435 13.411 1.00 51.55 ? 532 MAN B C5 1 HETATM 8382 C C6 . MAN Y 6 . ? 31.036 31.107 13.923 1.00 52.18 ? 532 MAN B C6 1 HETATM 8383 O O2 . MAN Y 6 . ? 33.596 31.391 10.067 1.00 50.12 ? 532 MAN B O2 1 HETATM 8384 O O3 . MAN Y 6 . ? 33.855 33.968 11.033 1.00 50.81 ? 532 MAN B O3 1 HETATM 8385 O O4 . MAN Y 6 . ? 32.080 33.820 13.277 1.00 50.79 ? 532 MAN B O4 1 HETATM 8386 O O5 . MAN Y 6 . ? 32.890 30.284 12.671 1.00 51.21 ? 532 MAN B O5 1 HETATM 8387 O O6 . MAN Y 6 . ? 31.008 29.829 14.542 1.00 52.62 ? 532 MAN B O6 1 HETATM 8388 C C1 . NDG Z 9 . ? 22.093 63.318 -16.048 1.00 40.31 ? 533 NDG B C1 1 HETATM 8389 C C2 . NDG Z 9 . ? 21.408 64.256 -17.055 1.00 42.38 ? 533 NDG B C2 1 HETATM 8390 C C3 . NDG Z 9 . ? 19.893 64.371 -16.833 1.00 43.59 ? 533 NDG B C3 1 HETATM 8391 C C4 . NDG Z 9 . ? 19.258 62.998 -16.648 1.00 43.53 ? 533 NDG B C4 1 HETATM 8392 C C5 . NDG Z 9 . ? 19.984 62.275 -15.517 1.00 43.24 ? 533 NDG B C5 1 HETATM 8393 C C6 . NDG Z 9 . ? 19.373 60.907 -15.224 1.00 43.66 ? 533 NDG B C6 1 HETATM 8394 C C7 . NDG Z 9 . ? 22.981 65.962 -17.727 1.00 45.02 ? 533 NDG B C7 1 HETATM 8395 C C8 . NDG Z 9 . ? 23.368 67.427 -17.697 1.00 44.73 ? 533 NDG B C8 1 HETATM 8396 O O . NDG Z 9 . ? 21.371 62.081 -15.881 1.00 42.30 ? 533 NDG B O 1 HETATM 8397 O O3 . NDG Z 9 . ? 19.284 65.020 -17.941 1.00 44.04 ? 533 NDG B O3 1 HETATM 8398 O O4 . NDG Z 9 . ? 17.871 63.116 -16.355 1.00 44.90 ? 533 NDG B O4 1 HETATM 8399 O O6 . NDG Z 9 . ? 19.113 60.738 -13.834 1.00 43.56 ? 533 NDG B O6 1 HETATM 8400 O O7 . NDG Z 9 . ? 23.581 65.180 -18.456 1.00 45.93 ? 533 NDG B O7 1 HETATM 8401 N N2 . NDG Z 9 . ? 21.979 65.588 -16.939 1.00 43.89 ? 533 NDG B N2 1 HETATM 8402 C C1 . NAG AA 4 . ? 34.945 27.074 -1.673 1.00 17.90 ? 534 NAG B C1 1 HETATM 8403 C C2 . NAG AA 4 . ? 33.493 27.416 -2.026 1.00 19.41 ? 534 NAG B C2 1 HETATM 8404 C C3 . NAG AA 4 . ? 32.625 26.151 -1.979 1.00 22.77 ? 534 NAG B C3 1 HETATM 8405 C C4 . NAG AA 4 . ? 33.256 24.993 -2.771 1.00 23.89 ? 534 NAG B C4 1 HETATM 8406 C C5 . NAG AA 4 . ? 34.734 24.813 -2.391 1.00 23.08 ? 534 NAG B C5 1 HETATM 8407 C C6 . NAG AA 4 . ? 35.451 23.778 -3.239 1.00 23.16 ? 534 NAG B C6 1 HETATM 8408 C C7 . NAG AA 4 . ? 32.654 29.613 -1.467 1.00 16.96 ? 534 NAG B C7 1 HETATM 8409 C C8 . NAG AA 4 . ? 31.789 30.426 -0.520 1.00 17.10 ? 534 NAG B C8 1 HETATM 8410 N N2 . NAG AA 4 . ? 32.986 28.386 -1.074 1.00 18.02 ? 534 NAG B N2 1 HETATM 8411 O O3 . NAG AA 4 . ? 31.344 26.443 -2.517 1.00 24.84 ? 534 NAG B O3 1 HETATM 8412 O O4 . NAG AA 4 . ? 32.536 23.773 -2.493 1.00 26.24 ? 534 NAG B O4 1 HETATM 8413 O O5 . NAG AA 4 . ? 35.442 26.061 -2.552 1.00 21.62 ? 534 NAG B O5 1 HETATM 8414 O O6 . NAG AA 4 . ? 35.694 24.262 -4.552 1.00 24.48 ? 534 NAG B O6 1 HETATM 8415 O O7 . NAG AA 4 . ? 33.011 30.096 -2.539 1.00 15.15 ? 534 NAG B O7 1 HETATM 8416 O O . HOH BA 10 . ? 97.535 -1.081 -20.383 1.00 32.41 ? 534 HOH A O 1 HETATM 8417 O O . HOH BA 10 . ? 59.332 12.894 -18.437 1.00 32.94 ? 535 HOH A O 1 HETATM 8418 O O . HOH BA 10 . ? 62.473 3.290 -46.814 1.00 32.16 ? 536 HOH A O 1 HETATM 8419 O O . HOH BA 10 . ? 58.447 7.260 -5.882 1.00 43.89 ? 537 HOH A O 1 HETATM 8420 O O . HOH BA 10 . ? 60.715 -17.456 -9.533 1.00 38.41 ? 538 HOH A O 1 HETATM 8421 O O . HOH BA 10 . ? 76.510 -30.483 -39.467 1.00 39.50 ? 539 HOH A O 1 HETATM 8422 O O . HOH BA 10 . ? 57.013 8.941 -9.871 1.00 33.48 ? 540 HOH A O 1 HETATM 8423 O O . HOH BA 10 . ? 95.235 -22.395 -35.439 1.00 33.05 ? 541 HOH A O 1 HETATM 8424 O O . HOH BA 10 . ? 90.070 -23.106 -32.186 1.00 43.66 ? 542 HOH A O 1 HETATM 8425 O O . HOH BA 10 . ? 51.012 11.954 -12.354 1.00 39.47 ? 543 HOH A O 1 HETATM 8426 O O . HOH BA 10 . ? 83.217 -27.826 -31.499 1.00 28.69 ? 544 HOH A O 1 HETATM 8427 O O . HOH BA 10 . ? 51.744 1.316 -9.884 1.00 19.19 ? 545 HOH A O 1 HETATM 8428 O O . HOH BA 10 . ? 64.903 1.873 -46.180 1.00 25.73 ? 546 HOH A O 1 HETATM 8429 O O . HOH BA 10 . ? 68.793 -3.687 -50.228 1.00 31.39 ? 547 HOH A O 1 HETATM 8430 O O . HOH BA 10 . ? 61.191 12.915 -24.344 1.00 26.74 ? 548 HOH A O 1 HETATM 8431 O O . HOH BA 10 . ? 46.569 7.517 -10.063 1.00 27.80 ? 549 HOH A O 1 HETATM 8432 O O . HOH BA 10 . ? 62.336 11.128 -22.277 1.00 40.07 ? 550 HOH A O 1 HETATM 8433 O O . HOH BA 10 . ? 77.741 7.295 -46.796 1.00 31.07 ? 551 HOH A O 1 HETATM 8434 O O . HOH BA 10 . ? 82.553 -18.744 -59.429 1.00 44.00 ? 552 HOH A O 1 HETATM 8435 O O . HOH BA 10 . ? 79.744 -20.072 -61.038 1.00 34.43 ? 553 HOH A O 1 HETATM 8436 O O . HOH BA 10 . ? 64.109 -12.990 -4.858 1.00 41.16 ? 554 HOH A O 1 HETATM 8437 O O . HOH BA 10 . ? 61.461 12.102 -42.412 1.00 34.35 ? 555 HOH A O 1 HETATM 8438 O O . HOH BA 10 . ? 97.162 3.307 -41.518 1.00 35.17 ? 556 HOH A O 1 HETATM 8439 O O . HOH BA 10 . ? 67.982 3.402 -8.041 1.00 36.22 ? 557 HOH A O 1 HETATM 8440 O O . HOH BA 10 . ? 47.203 4.985 -9.818 1.00 33.25 ? 558 HOH A O 1 HETATM 8441 O O . HOH BA 10 . ? 55.111 -8.854 -5.194 1.00 31.72 ? 559 HOH A O 1 HETATM 8442 O O . HOH BA 10 . ? 48.709 13.123 -39.868 1.00 29.94 ? 560 HOH A O 1 HETATM 8443 O O . HOH BA 10 . ? 67.354 -6.667 -6.922 1.00 29.76 ? 561 HOH A O 1 HETATM 8444 O O . HOH BA 10 . ? 91.722 -26.818 -27.815 1.00 38.78 ? 562 HOH A O 1 HETATM 8445 O O . HOH BA 10 . ? 60.516 17.235 -29.095 1.00 33.17 ? 563 HOH A O 1 HETATM 8446 O O . HOH BA 10 . ? 61.709 9.797 -40.824 1.00 28.56 ? 564 HOH A O 1 HETATM 8447 O O . HOH BA 10 . ? 84.345 -8.018 -12.815 1.00 42.05 ? 565 HOH A O 1 HETATM 8448 O O . HOH BA 10 . ? 83.077 10.353 -36.666 1.00 34.52 ? 566 HOH A O 1 HETATM 8449 O O . HOH BA 10 . ? 87.060 -8.204 -19.509 1.00 39.86 ? 567 HOH A O 1 HETATM 8450 O O . HOH BA 10 . ? 70.832 -21.595 -8.144 1.00 40.86 ? 568 HOH A O 1 HETATM 8451 O O . HOH BA 10 . ? 43.877 -14.024 -19.628 1.00 40.45 ? 569 HOH A O 1 HETATM 8452 O O . HOH BA 10 . ? 40.043 13.099 -34.946 1.00 40.52 ? 570 HOH A O 1 HETATM 8453 O O . HOH BA 10 . ? 88.269 -19.803 -13.994 1.00 36.91 ? 571 HOH A O 1 HETATM 8454 O O . HOH BA 10 . ? 95.872 -20.710 -39.881 1.00 37.20 ? 572 HOH A O 1 HETATM 8455 O O . HOH BA 10 . ? 40.094 -18.537 -32.108 1.00 37.37 ? 573 HOH A O 1 HETATM 8456 O O . HOH BA 10 . ? 47.354 -2.210 -43.448 1.00 39.43 ? 574 HOH A O 1 HETATM 8457 O O . HOH BA 10 . ? 76.560 -5.443 -7.587 1.00 47.25 ? 575 HOH A O 1 HETATM 8458 O O . HOH BA 10 . ? 91.282 -6.436 -18.289 1.00 41.10 ? 576 HOH A O 1 HETATM 8459 O O . HOH BA 10 . ? 68.853 1.654 -6.141 1.00 38.94 ? 577 HOH A O 1 HETATM 8460 O O . HOH BA 10 . ? 61.527 -1.335 -5.402 1.00 36.40 ? 578 HOH A O 1 HETATM 8461 O O . HOH BA 10 . ? 57.736 -24.022 -42.680 1.00 42.67 ? 579 HOH A O 1 HETATM 8462 O O . HOH BA 10 . ? 39.061 -13.400 -17.347 1.00 33.48 ? 580 HOH A O 1 HETATM 8463 O O . HOH BA 10 . ? 66.068 11.139 -15.712 1.00 36.42 ? 581 HOH A O 1 HETATM 8464 O O . HOH BA 10 . ? 36.046 -3.802 -14.170 1.00 41.07 ? 582 HOH A O 1 HETATM 8465 O O . HOH BA 10 . ? 75.721 -29.070 -27.302 1.00 39.09 ? 583 HOH A O 1 HETATM 8466 O O . HOH BA 10 . ? 75.936 -13.932 -6.537 1.00 44.63 ? 584 HOH A O 1 HETATM 8467 O O . HOH BA 10 . ? 34.656 -19.343 -31.620 1.00 36.42 ? 585 HOH A O 1 HETATM 8468 O O . HOH BA 10 . ? 90.501 -1.083 -20.196 1.00 27.67 ? 586 HOH A O 1 HETATM 8469 O O . HOH BA 10 . ? 58.165 -24.867 -36.402 1.00 29.36 ? 587 HOH A O 1 HETATM 8470 O O . HOH BA 10 . ? 55.779 -17.183 -8.990 1.00 34.45 ? 588 HOH A O 1 HETATM 8471 O O . HOH BA 10 . ? 70.540 -22.824 -52.819 1.00 42.37 ? 589 HOH A O 1 HETATM 8472 O O . HOH BA 10 . ? 71.321 1.099 -24.084 1.00 8.71 ? 590 HOH A O 1 HETATM 8473 O O . HOH BA 10 . ? 82.004 -27.246 -52.850 1.00 38.48 ? 591 HOH A O 1 HETATM 8474 O O . HOH BA 10 . ? 62.781 -24.937 -34.192 1.00 34.46 ? 592 HOH A O 1 HETATM 8475 O O . HOH BA 10 . ? 71.176 -6.396 -35.053 1.00 7.98 ? 593 HOH A O 1 HETATM 8476 O O . HOH BA 10 . ? 71.121 -28.352 -31.934 1.00 35.45 ? 594 HOH A O 1 HETATM 8477 O O . HOH BA 10 . ? 68.602 -5.309 -44.233 1.00 22.56 ? 595 HOH A O 1 HETATM 8478 O O . HOH BA 10 . ? 62.766 13.544 -31.173 1.00 25.80 ? 596 HOH A O 1 HETATM 8479 O O . HOH BA 10 . ? 75.042 13.551 -23.209 1.00 31.28 ? 597 HOH A O 1 HETATM 8480 O O . HOH BA 10 . ? 39.852 7.708 -32.337 1.00 30.90 ? 598 HOH A O 1 HETATM 8481 O O . HOH BA 10 . ? 89.074 -26.113 -48.627 1.00 28.74 ? 599 HOH A O 1 HETATM 8482 O O . HOH BA 10 . ? 53.382 -2.610 -45.570 1.00 31.03 ? 600 HOH A O 1 HETATM 8483 O O . HOH BA 10 . ? 88.579 9.398 -45.252 1.00 28.83 ? 601 HOH A O 1 HETATM 8484 O O . HOH BA 10 . ? 64.363 -25.585 -22.753 1.00 24.76 ? 602 HOH A O 1 HETATM 8485 O O . HOH BA 10 . ? 69.206 2.246 -45.372 1.00 32.26 ? 603 HOH A O 1 HETATM 8486 O O . HOH BA 10 . ? 68.380 -1.577 -57.678 1.00 35.70 ? 604 HOH A O 1 HETATM 8487 O O . HOH BA 10 . ? 102.605 -2.479 -38.264 1.00 29.60 ? 605 HOH A O 1 HETATM 8488 O O . HOH BA 10 . ? 57.587 -24.402 -39.047 1.00 29.89 ? 606 HOH A O 1 HETATM 8489 O O . HOH BA 10 . ? 39.171 11.875 -19.433 1.00 31.03 ? 607 HOH A O 1 HETATM 8490 O O . HOH BA 10 . ? 68.901 -26.141 -35.192 1.00 29.43 ? 608 HOH A O 1 HETATM 8491 O O . HOH BA 10 . ? 53.496 8.978 -37.320 1.00 26.15 ? 609 HOH A O 1 HETATM 8492 O O . HOH BA 10 . ? 60.533 9.961 -13.065 1.00 31.38 ? 610 HOH A O 1 HETATM 8493 O O . HOH BA 10 . ? 64.362 -27.435 -28.485 1.00 45.75 ? 611 HOH A O 1 HETATM 8494 O O . HOH BA 10 . ? 87.569 -26.296 -21.955 1.00 33.72 ? 612 HOH A O 1 HETATM 8495 O O . HOH BA 10 . ? 55.443 -0.003 -25.907 1.00 27.97 ? 613 HOH A O 1 HETATM 8496 O O . HOH BA 10 . ? 61.782 -23.894 -44.529 1.00 25.98 ? 614 HOH A O 1 HETATM 8497 O O . HOH BA 10 . ? 81.020 -13.794 -8.384 1.00 27.47 ? 615 HOH A O 1 HETATM 8498 O O . HOH BA 10 . ? 43.681 18.221 -16.224 1.00 39.67 ? 616 HOH A O 1 HETATM 8499 O O . HOH BA 10 . ? 102.011 -3.414 -45.249 1.00 30.69 ? 617 HOH A O 1 HETATM 8500 O O . HOH BA 10 . ? 97.451 -20.671 -41.982 1.00 28.59 ? 618 HOH A O 1 HETATM 8501 O O . HOH BA 10 . ? 81.501 -21.816 -26.649 1.00 25.49 ? 619 HOH A O 1 HETATM 8502 O O . HOH BA 10 . ? 98.554 -3.964 -35.045 1.00 27.23 ? 620 HOH A O 1 HETATM 8503 O O . HOH BA 10 . ? 42.854 -13.018 -17.054 1.00 34.42 ? 621 HOH A O 1 HETATM 8504 O O . HOH BA 10 . ? 42.157 -0.398 -40.740 1.00 31.62 ? 622 HOH A O 1 HETATM 8505 O O . HOH BA 10 . ? 80.549 -7.948 -59.241 1.00 30.76 ? 623 HOH A O 1 HETATM 8506 O O . HOH BA 10 . ? 36.873 -17.623 -35.243 1.00 29.14 ? 624 HOH A O 1 HETATM 8507 O O . HOH BA 10 . ? 59.430 -14.403 -38.588 1.00 7.37 ? 625 HOH A O 1 HETATM 8508 O O . HOH BA 10 . ? 56.588 19.954 -35.729 1.00 28.28 ? 626 HOH A O 1 HETATM 8509 O O . HOH BA 10 . ? 77.100 -24.400 -13.563 1.00 41.38 ? 627 HOH A O 1 HETATM 8510 O O . HOH BA 10 . ? 95.951 -14.230 -47.424 1.00 30.58 ? 628 HOH A O 1 HETATM 8511 O O . HOH BA 10 . ? 58.509 -20.148 -43.814 1.00 29.32 ? 629 HOH A O 1 HETATM 8512 O O . HOH BA 10 . ? 94.413 -12.341 -48.641 1.00 38.03 ? 630 HOH A O 1 HETATM 8513 O O . HOH BA 10 . ? 77.008 10.910 -11.755 1.00 41.66 ? 631 HOH A O 1 HETATM 8514 O O . HOH BA 10 . ? 58.296 -26.005 -21.055 1.00 35.30 ? 632 HOH A O 1 HETATM 8515 O O . HOH BA 10 . ? 63.086 -22.889 -26.774 1.00 31.43 ? 633 HOH A O 1 HETATM 8516 O O . HOH BA 10 . ? 57.390 -2.939 -49.670 1.00 37.92 ? 634 HOH A O 1 HETATM 8517 O O . HOH BA 10 . ? 80.995 -29.788 -48.751 1.00 34.13 ? 635 HOH A O 1 HETATM 8518 O O . HOH BA 10 . ? 59.859 -16.092 -50.206 1.00 36.79 ? 636 HOH A O 1 HETATM 8519 O O . HOH BA 10 . ? 40.005 -7.105 -17.182 1.00 35.33 ? 637 HOH A O 1 HETATM 8520 O O . HOH BA 10 . ? 47.178 -15.676 -14.589 1.00 31.79 ? 638 HOH A O 1 HETATM 8521 O O . HOH BA 10 . ? 87.758 9.813 -30.705 1.00 36.57 ? 639 HOH A O 1 HETATM 8522 O O . HOH BA 10 . ? 63.406 14.179 -42.111 1.00 33.37 ? 640 HOH A O 1 HETATM 8523 O O . HOH BA 10 . ? 52.045 -15.812 -45.304 1.00 29.20 ? 641 HOH A O 1 HETATM 8524 O O . HOH BA 10 . ? 70.723 -0.561 -7.413 1.00 28.31 ? 642 HOH A O 1 HETATM 8525 O O . HOH BA 10 . ? 90.885 -10.611 -15.924 1.00 42.41 ? 643 HOH A O 1 HETATM 8526 O O . HOH BA 10 . ? 68.205 -7.340 -9.260 1.00 30.48 ? 644 HOH A O 1 HETATM 8527 O O . HOH BA 10 . ? 59.485 1.289 -48.883 1.00 27.26 ? 645 HOH A O 1 HETATM 8528 O O . HOH BA 10 . ? 44.996 14.834 -28.080 1.00 32.11 ? 646 HOH A O 1 HETATM 8529 O O . HOH BA 10 . ? 54.495 -0.886 -44.175 1.00 37.69 ? 647 HOH A O 1 HETATM 8530 O O . HOH BA 10 . ? 31.649 -1.288 -20.276 1.00 28.73 ? 648 HOH A O 1 HETATM 8531 O O . HOH BA 10 . ? 53.760 -10.179 -47.557 1.00 34.80 ? 649 HOH A O 1 HETATM 8532 O O . HOH BA 10 . ? 47.472 13.347 -33.101 1.00 35.27 ? 650 HOH A O 1 HETATM 8533 O O . HOH BA 10 . ? 97.448 -17.159 -20.503 1.00 33.02 ? 651 HOH A O 1 HETATM 8534 O O . HOH BA 10 . ? 81.284 -5.587 -13.724 1.00 31.41 ? 652 HOH A O 1 HETATM 8535 O O . HOH BA 10 . ? 76.196 -29.115 -48.130 1.00 38.08 ? 653 HOH A O 1 HETATM 8536 O O . HOH BA 10 . ? 80.013 -12.254 -10.189 1.00 38.37 ? 654 HOH A O 1 HETATM 8537 O O . HOH BA 10 . ? 78.882 -17.982 -8.784 1.00 31.73 ? 655 HOH A O 1 HETATM 8538 O O . HOH BA 10 . ? 97.416 -3.403 -19.083 1.00 35.45 ? 656 HOH A O 1 HETATM 8539 O O . HOH BA 10 . ? 59.334 9.010 -24.630 1.00 40.73 ? 657 HOH A O 1 HETATM 8540 O O . HOH BA 10 . ? 61.432 3.806 -6.956 1.00 29.64 ? 658 HOH A O 1 HETATM 8541 O O . HOH BA 10 . ? 96.134 2.778 -26.515 1.00 37.77 ? 659 HOH A O 1 HETATM 8542 O O . HOH BA 10 . ? 84.741 -26.905 -49.227 1.00 27.61 ? 660 HOH A O 1 HETATM 8543 O O . HOH BA 10 . ? 82.303 -29.963 -53.504 1.00 38.16 ? 661 HOH A O 1 HETATM 8544 O O . HOH BA 10 . ? 102.816 -7.187 -41.669 1.00 36.15 ? 662 HOH A O 1 HETATM 8545 O O . HOH BA 10 . ? 89.243 -28.011 -23.586 1.00 37.71 ? 663 HOH A O 1 HETATM 8546 O O . HOH BA 10 . ? 65.612 11.322 -19.158 1.00 36.04 ? 664 HOH A O 1 HETATM 8547 O O . HOH BA 10 . ? 47.744 -16.931 -25.455 1.00 35.16 ? 665 HOH A O 1 HETATM 8548 O O . HOH BA 10 . ? 82.599 -16.540 -63.605 1.00 37.39 ? 666 HOH A O 1 HETATM 8549 O O . HOH BA 10 . ? 100.477 -10.868 -40.836 1.00 42.62 ? 667 HOH A O 1 HETATM 8550 O O . HOH BA 10 . ? 69.982 -18.732 -50.223 1.00 29.17 ? 668 HOH A O 1 HETATM 8551 O O . HOH BA 10 . ? 98.130 1.509 -36.738 1.00 35.02 ? 669 HOH A O 1 HETATM 8552 O O . HOH BA 10 . ? 62.190 10.107 -44.045 1.00 33.86 ? 670 HOH A O 1 HETATM 8553 O O . HOH BA 10 . ? 98.775 -15.143 -39.144 1.00 44.85 ? 671 HOH A O 1 HETATM 8554 O O . HOH BA 10 . ? 97.264 -17.829 -44.340 1.00 42.81 ? 672 HOH A O 1 HETATM 8555 O O . HOH BA 10 . ? 74.987 8.424 -8.664 1.00 38.30 ? 673 HOH A O 1 HETATM 8556 O O . HOH BA 10 . ? 61.171 -10.214 -7.385 1.00 44.11 ? 674 HOH A O 1 HETATM 8557 O O . HOH BA 10 . ? 89.606 7.394 -30.240 1.00 42.22 ? 675 HOH A O 1 HETATM 8558 O O . HOH BA 10 . ? 61.149 -18.997 -14.919 1.00 32.90 ? 676 HOH A O 1 HETATM 8559 O O . HOH BA 10 . ? 78.463 -1.845 -9.736 1.00 31.14 ? 677 HOH A O 1 HETATM 8560 O O . HOH BA 10 . ? 55.663 -5.208 -49.860 1.00 37.36 ? 678 HOH A O 1 HETATM 8561 O O . HOH BA 10 . ? 58.472 -7.616 -25.387 1.00 36.45 ? 679 HOH A O 1 HETATM 8562 O O . HOH BA 10 . ? 44.216 6.948 -39.076 1.00 34.56 ? 680 HOH A O 1 HETATM 8563 O O . HOH BA 10 . ? 85.103 12.347 -26.815 1.00 40.17 ? 681 HOH A O 1 HETATM 8564 O O . HOH BA 10 . ? 62.548 -14.364 -9.401 1.00 37.52 ? 682 HOH A O 1 HETATM 8565 O O . HOH BA 10 . ? 56.430 -26.971 -39.773 1.00 36.70 ? 683 HOH A O 1 HETATM 8566 O O . HOH BA 10 . ? 93.624 2.795 -19.875 1.00 44.70 ? 684 HOH A O 1 HETATM 8567 O O . HOH BA 10 . ? 90.601 -20.217 -18.089 1.00 38.19 ? 685 HOH A O 1 HETATM 8568 O O . HOH BA 10 . ? 60.231 -33.321 -35.857 1.00 47.89 ? 686 HOH A O 1 HETATM 8569 O O . HOH BA 10 . ? 63.588 15.378 -37.804 1.00 37.97 ? 687 HOH A O 1 HETATM 8570 O O . HOH BA 10 . ? 79.670 3.962 -10.860 1.00 34.62 ? 688 HOH A O 1 HETATM 8571 O O . HOH BA 10 . ? 43.853 -17.115 -24.710 1.00 35.06 ? 689 HOH A O 1 HETATM 8572 O O . HOH BA 10 . ? 54.546 11.788 -22.994 1.00 30.43 ? 690 HOH A O 1 HETATM 8573 O O . HOH BA 10 . ? 52.484 -6.757 -44.246 1.00 36.06 ? 691 HOH A O 1 HETATM 8574 O O . HOH BA 10 . ? 53.240 -17.579 -12.145 1.00 30.06 ? 692 HOH A O 1 HETATM 8575 O O . HOH BA 10 . ? 83.487 -20.362 -11.158 1.00 36.53 ? 693 HOH A O 1 HETATM 8576 O O . HOH BA 10 . ? 67.097 -7.295 -22.385 1.00 6.89 ? 694 HOH A O 1 HETATM 8577 O O . HOH BA 10 . ? 38.105 -6.203 -19.738 1.00 32.98 ? 695 HOH A O 1 HETATM 8578 O O . HOH BA 10 . ? 86.732 -0.697 -16.239 1.00 33.90 ? 696 HOH A O 1 HETATM 8579 O O . HOH BA 10 . ? 58.048 10.041 -43.722 1.00 29.63 ? 697 HOH A O 1 HETATM 8580 O O . HOH BA 10 . ? 70.693 -24.659 -13.089 1.00 38.82 ? 698 HOH A O 1 HETATM 8581 O O . HOH BA 10 . ? 54.513 -14.130 -36.908 1.00 7.97 ? 699 HOH A O 1 HETATM 8582 O O . HOH BA 10 . ? 62.627 -3.675 -49.694 1.00 39.17 ? 700 HOH A O 1 HETATM 8583 O O . HOH BA 10 . ? 86.386 -28.807 -46.795 1.00 36.64 ? 701 HOH A O 1 HETATM 8584 O O . HOH BA 10 . ? 61.355 -20.673 -26.712 1.00 43.10 ? 702 HOH A O 1 HETATM 8585 O O . HOH BA 10 . ? 69.334 -24.428 -17.176 1.00 36.09 ? 703 HOH A O 1 HETATM 8586 O O . HOH BA 10 . ? 103.909 -11.022 -43.012 1.00 39.55 ? 704 HOH A O 1 HETATM 8587 O O . HOH BA 10 . ? 57.025 -13.234 -37.556 1.00 7.80 ? 705 HOH A O 1 HETATM 8588 O O . HOH BA 10 . ? 93.879 5.840 -20.279 1.00 44.17 ? 706 HOH A O 1 HETATM 8589 O O . HOH BA 10 . ? 60.804 -10.073 -19.561 1.00 9.33 ? 707 HOH A O 1 HETATM 8590 O O . HOH BA 10 . ? 70.885 3.262 -5.380 1.00 33.72 ? 708 HOH A O 1 HETATM 8591 O O . HOH BA 10 . ? 47.579 -13.525 -20.401 1.00 19.85 ? 709 HOH A O 1 HETATM 8592 O O . HOH BA 10 . ? 95.839 -29.473 -46.447 1.00 33.24 ? 710 HOH A O 1 HETATM 8593 O O . HOH BA 10 . ? 63.053 9.519 -14.445 1.00 30.77 ? 711 HOH A O 1 HETATM 8594 O O . HOH BA 10 . ? 58.201 -20.187 -28.904 1.00 35.17 ? 712 HOH A O 1 HETATM 8595 O O . HOH BA 10 . ? 97.834 -18.019 -41.640 1.00 34.64 ? 713 HOH A O 1 HETATM 8596 O O . HOH BA 10 . ? 49.876 -12.861 -17.954 1.00 32.08 ? 714 HOH A O 1 HETATM 8597 O O . HOH BA 10 . ? 100.590 1.202 -37.513 1.00 41.61 ? 715 HOH A O 1 HETATM 8598 O O . HOH BA 10 . ? 58.483 14.107 -16.199 1.00 36.92 ? 716 HOH A O 1 HETATM 8599 O O . HOH BA 10 . ? 81.031 -9.723 -11.158 1.00 41.78 ? 717 HOH A O 1 HETATM 8600 O O . HOH BA 10 . ? 38.476 14.401 -19.901 1.00 35.66 ? 718 HOH A O 1 HETATM 8601 O O . HOH BA 10 . ? 81.057 -2.655 -9.263 1.00 38.60 ? 719 HOH A O 1 HETATM 8602 O O . HOH BA 10 . ? 85.542 10.807 -38.379 1.00 37.54 ? 720 HOH A O 1 HETATM 8603 O O . HOH BA 10 . ? 68.893 14.298 -16.144 1.00 32.42 ? 721 HOH A O 1 HETATM 8604 O O . HOH BA 10 . ? 38.433 -11.373 -15.693 1.00 45.14 ? 722 HOH A O 1 HETATM 8605 O O . HOH BA 10 . ? 70.109 -28.576 -25.655 1.00 43.25 ? 723 HOH A O 1 HETATM 8606 O O . HOH BA 10 . ? 68.702 -23.622 -58.211 1.00 41.27 ? 724 HOH A O 1 HETATM 8607 O O . HOH BA 10 . ? 89.202 7.807 -32.747 1.00 46.24 ? 725 HOH A O 1 HETATM 8608 O O . HOH BA 10 . ? 74.978 13.748 -14.413 1.00 41.86 ? 726 HOH A O 1 HETATM 8609 O O . HOH BA 10 . ? 86.504 10.772 -33.457 1.00 36.00 ? 727 HOH A O 1 HETATM 8610 O O . HOH BA 10 . ? 76.349 12.318 -18.348 1.00 41.26 ? 728 HOH A O 1 HETATM 8611 O O . HOH BA 10 . ? 66.328 6.391 -46.657 1.00 36.41 ? 729 HOH A O 1 HETATM 8612 O O . HOH BA 10 . ? 72.060 16.922 -28.332 1.00 36.72 ? 730 HOH A O 1 HETATM 8613 O O . HOH BA 10 . ? 70.454 -25.438 -50.562 1.00 40.41 ? 731 HOH A O 1 HETATM 8614 O O . HOH BA 10 . ? 61.908 9.503 -16.928 1.00 35.00 ? 732 HOH A O 1 HETATM 8615 O O . HOH BA 10 . ? 74.468 9.777 -48.315 1.00 31.12 ? 733 HOH A O 1 HETATM 8616 O O . HOH BA 10 . ? 83.498 -25.494 -54.075 1.00 35.26 ? 734 HOH A O 1 HETATM 8617 O O . HOH BA 10 . ? 82.752 -27.081 -22.086 1.00 41.10 ? 735 HOH A O 1 HETATM 8618 O O . HOH BA 10 . ? 103.692 -9.396 -47.508 1.00 34.96 ? 736 HOH A O 1 HETATM 8619 O O . HOH BA 10 . ? 41.620 8.234 -35.436 1.00 32.47 ? 737 HOH A O 1 HETATM 8620 O O . HOH BA 10 . ? 67.006 -9.964 -55.595 1.00 37.01 ? 738 HOH A O 1 HETATM 8621 O O . HOH BA 10 . ? 45.526 4.711 -39.812 1.00 43.95 ? 739 HOH A O 1 HETATM 8622 O O . HOH BA 10 . ? 66.672 -4.999 -46.372 1.00 34.46 ? 740 HOH A O 1 HETATM 8623 O O . HOH BA 10 . ? 63.064 -22.481 -15.037 1.00 39.00 ? 741 HOH A O 1 HETATM 8624 O O . HOH BA 10 . ? 64.876 10.744 -45.166 1.00 39.04 ? 742 HOH A O 1 HETATM 8625 O O . HOH BA 10 . ? 66.740 -12.582 -53.286 1.00 33.91 ? 743 HOH A O 1 HETATM 8626 O O . HOH BA 10 . ? 77.770 16.130 -33.201 1.00 39.19 ? 744 HOH A O 1 HETATM 8627 O O . HOH BA 10 . ? 61.279 -24.064 -37.265 1.00 33.61 ? 745 HOH A O 1 HETATM 8628 O O . HOH BA 10 . ? 55.989 -24.739 -30.024 1.00 38.47 ? 746 HOH A O 1 HETATM 8629 O O . HOH BA 10 . ? 79.639 1.488 -51.488 1.00 41.85 ? 747 HOH A O 1 HETATM 8630 O O . HOH BA 10 . ? 73.468 -25.265 -59.285 1.00 42.46 ? 748 HOH A O 1 HETATM 8631 O O . HOH BA 10 . ? 69.648 -12.601 -9.151 1.00 40.12 ? 749 HOH A O 1 HETATM 8632 O O . HOH BA 10 . ? 79.431 -28.899 -46.696 1.00 37.40 ? 750 HOH A O 1 HETATM 8633 O O . HOH BA 10 . ? 96.169 -23.366 -39.032 1.00 41.49 ? 751 HOH A O 1 HETATM 8634 O O . HOH BA 10 . ? 74.123 14.132 -36.739 1.00 31.37 ? 752 HOH A O 1 HETATM 8635 O O . HOH BA 10 . ? 84.085 -13.312 -54.360 1.00 41.04 ? 753 HOH A O 1 HETATM 8636 O O . HOH BA 10 . ? 60.344 6.955 -45.293 1.00 31.22 ? 754 HOH A O 1 HETATM 8637 O O . HOH BA 10 . ? 85.510 -5.337 -52.632 1.00 39.25 ? 755 HOH A O 1 HETATM 8638 O O . HOH BA 10 . ? 83.627 -7.094 -53.541 1.00 37.84 ? 756 HOH A O 1 HETATM 8639 O O . HOH BA 10 . ? 80.686 -26.992 -24.547 1.00 41.86 ? 757 HOH A O 1 HETATM 8640 O O . HOH BA 10 . ? 46.172 -16.700 -23.269 1.00 34.57 ? 758 HOH A O 1 HETATM 8641 O O . HOH BA 10 . ? 61.388 9.009 -9.177 1.00 41.11 ? 759 HOH A O 1 HETATM 8642 O O . HOH BA 10 . ? 68.688 -28.750 -34.450 1.00 38.11 ? 760 HOH A O 1 HETATM 8643 O O . HOH BA 10 . ? 92.376 -23.270 -30.923 1.00 48.49 ? 761 HOH A O 1 HETATM 8644 O O . HOH BA 10 . ? 38.315 11.213 -34.477 1.00 38.98 ? 762 HOH A O 1 HETATM 8645 O O . HOH BA 10 . ? 63.559 -28.256 -22.098 1.00 40.86 ? 763 HOH A O 1 HETATM 8646 O O . HOH BA 10 . ? 29.730 2.863 -27.496 1.00 31.95 ? 764 HOH A O 1 HETATM 8647 O O . HOH BA 10 . ? 54.827 14.470 -42.075 1.00 43.68 ? 765 HOH A O 1 HETATM 8648 O O . HOH BA 10 . ? 81.594 14.473 -34.158 1.00 38.47 ? 766 HOH A O 1 HETATM 8649 O O . HOH BA 10 . ? 46.564 12.873 -36.058 1.00 32.45 ? 767 HOH A O 1 HETATM 8650 O O . HOH BA 10 . ? 96.182 0.650 -28.396 1.00 38.30 ? 768 HOH A O 1 HETATM 8651 O O . HOH BA 10 . ? 53.563 -16.804 -7.379 1.00 44.33 ? 769 HOH A O 1 HETATM 8652 O O . HOH BA 10 . ? 83.291 -31.004 -39.827 1.00 38.08 ? 770 HOH A O 1 HETATM 8653 O O . HOH BA 10 . ? 34.113 -0.291 -15.334 1.00 37.45 ? 771 HOH A O 1 HETATM 8654 O O . HOH BA 10 . ? 88.345 -18.354 -18.574 1.00 33.70 ? 772 HOH A O 1 HETATM 8655 O O . HOH BA 10 . ? 92.221 -8.426 -16.946 1.00 45.63 ? 773 HOH A O 1 HETATM 8656 O O . HOH BA 10 . ? 92.503 -20.444 -49.765 1.00 39.19 ? 774 HOH A O 1 HETATM 8657 O O . HOH BA 10 . ? 91.329 -5.654 -51.667 1.00 35.71 ? 775 HOH A O 1 HETATM 8658 O O . HOH BA 10 . ? 69.180 -1.024 -49.867 1.00 39.76 ? 776 HOH A O 1 HETATM 8659 O O . HOH BA 10 . ? 73.435 -3.962 -36.726 1.00 7.22 ? 777 HOH A O 1 HETATM 8660 O O . HOH BA 10 . ? 94.839 -17.701 -47.803 1.00 39.03 ? 778 HOH A O 1 HETATM 8661 O O . HOH BA 10 . ? 71.528 0.291 -52.836 1.00 43.15 ? 779 HOH A O 1 HETATM 8662 O O . HOH BA 10 . ? 34.486 4.037 -19.386 1.00 35.10 ? 780 HOH A O 1 HETATM 8663 O O . HOH BA 10 . ? 84.938 -22.050 -58.007 1.00 43.33 ? 781 HOH A O 1 HETATM 8664 O O . HOH BA 10 . ? 52.249 7.410 -9.410 1.00 35.56 ? 782 HOH A O 1 HETATM 8665 O O . HOH BA 10 . ? 100.245 -13.502 -40.632 1.00 45.61 ? 783 HOH A O 1 HETATM 8666 O O . HOH BA 10 . ? 58.973 -25.089 -32.232 1.00 38.32 ? 784 HOH A O 1 HETATM 8667 O O . HOH BA 10 . ? 80.237 -16.970 -65.166 1.00 31.65 ? 785 HOH A O 1 HETATM 8668 O O . HOH BA 10 . ? 100.832 -3.862 -19.814 1.00 40.75 ? 786 HOH A O 1 HETATM 8669 O O . HOH BA 10 . ? 80.664 6.421 -45.340 1.00 38.98 ? 787 HOH A O 1 HETATM 8670 O O . HOH BA 10 . ? 73.380 14.805 -34.060 1.00 47.03 ? 788 HOH A O 1 HETATM 8671 O O . HOH BA 10 . ? 39.344 15.076 -29.099 1.00 37.51 ? 789 HOH A O 1 HETATM 8672 O O . HOH BA 10 . ? 35.047 -2.464 -18.295 1.00 46.02 ? 790 HOH A O 1 HETATM 8673 O O . HOH BA 10 . ? 101.637 0.372 -39.879 1.00 38.25 ? 791 HOH A O 1 HETATM 8674 O O . HOH BA 10 . ? 86.239 -26.215 -18.515 1.00 47.38 ? 792 HOH A O 1 HETATM 8675 O O . HOH BA 10 . ? 70.747 15.077 -38.419 1.00 38.19 ? 793 HOH A O 1 HETATM 8676 O O . HOH BA 10 . ? 78.698 16.783 -28.124 1.00 43.42 ? 794 HOH A O 1 HETATM 8677 O O . HOH BA 10 . ? 36.640 8.978 -34.366 1.00 38.70 ? 795 HOH A O 1 HETATM 8678 O O . HOH BA 10 . ? 89.671 -16.189 -17.252 1.00 39.39 ? 796 HOH A O 1 HETATM 8679 O O . HOH BA 10 . ? 86.733 -3.652 -54.676 1.00 45.29 ? 797 HOH A O 1 HETATM 8680 O O . HOH BA 10 . ? 51.329 -8.085 -46.278 1.00 44.51 ? 798 HOH A O 1 HETATM 8681 O O . HOH BA 10 . ? 77.440 11.816 -43.933 1.00 39.34 ? 799 HOH A O 1 HETATM 8682 O O . HOH BA 10 . ? 95.400 -6.986 -51.509 1.00 40.81 ? 800 HOH A O 1 HETATM 8683 O O . HOH BA 10 . ? 62.082 -14.253 -50.032 1.00 45.15 ? 801 HOH A O 1 HETATM 8684 O O . HOH BA 10 . ? 48.369 8.775 -11.826 1.00 47.00 ? 802 HOH A O 1 HETATM 8685 O O . HOH BA 10 . ? 75.241 -31.980 -42.145 1.00 45.56 ? 803 HOH A O 1 HETATM 8686 O O . HOH BA 10 . ? 84.171 -30.367 -31.467 1.00 46.58 ? 804 HOH A O 1 HETATM 8687 O O . HOH BA 10 . ? 59.303 9.806 -17.138 1.00 44.28 ? 805 HOH A O 1 HETATM 8688 O O . HOH BA 10 . ? 74.498 13.677 -39.313 1.00 47.56 ? 806 HOH A O 1 HETATM 8689 O O . HOH BA 10 . ? 95.938 2.622 -21.208 1.00 38.19 ? 807 HOH A O 1 HETATM 8690 O O . HOH BA 10 . ? 51.045 10.353 -43.186 1.00 41.34 ? 808 HOH A O 1 HETATM 8691 O O . HOH BA 10 . ? 72.936 -26.761 -18.430 1.00 42.04 ? 809 HOH A O 1 HETATM 8692 O O . HOH BA 10 . ? 56.470 -6.574 -4.815 1.00 40.98 ? 810 HOH A O 1 HETATM 8693 O O . HOH BA 10 . ? 52.491 15.859 -17.425 1.00 39.08 ? 811 HOH A O 1 HETATM 8694 O O . HOH BA 10 . ? 72.506 -10.725 -8.524 1.00 32.91 ? 812 HOH A O 1 HETATM 8695 O O . HOH BA 10 . ? 78.313 14.282 -38.496 1.00 47.62 ? 813 HOH A O 1 HETATM 8696 O O . HOH BA 10 . ? 59.705 -18.022 -17.088 1.00 36.25 ? 814 HOH A O 1 HETATM 8697 O O . HOH BA 10 . ? 97.772 4.625 -29.250 1.00 35.82 ? 815 HOH A O 1 HETATM 8698 O O . HOH BA 10 . ? 32.460 1.988 -18.643 1.00 44.19 ? 816 HOH A O 1 HETATM 8699 O O . HOH BA 10 . ? 86.385 -16.642 -50.809 1.00 39.83 ? 817 HOH A O 1 HETATM 8700 O O . HOH BA 10 . ? 61.356 8.598 -23.152 1.00 40.35 ? 818 HOH A O 1 HETATM 8701 O O . HOH BA 10 . ? 68.508 15.809 -22.584 1.00 40.59 ? 819 HOH A O 1 HETATM 8702 O O . HOH BA 10 . ? 61.496 -18.664 -47.336 1.00 38.44 ? 820 HOH A O 1 HETATM 8703 O O . HOH BA 10 . ? 56.361 -19.276 -45.110 1.00 39.21 ? 821 HOH A O 1 HETATM 8704 O O . HOH BA 10 . ? 88.279 -19.026 -56.556 1.00 33.18 ? 822 HOH A O 1 HETATM 8705 O O . HOH BA 10 . ? 73.039 -3.777 -55.493 1.00 33.48 ? 823 HOH A O 1 HETATM 8706 O O . HOH BA 10 . ? 46.247 15.236 -30.691 1.00 38.73 ? 824 HOH A O 1 HETATM 8707 O O . HOH BA 10 . ? 96.448 -17.398 -17.484 1.00 37.54 ? 825 HOH A O 1 HETATM 8708 O O . HOH BA 10 . ? 60.682 -5.828 -40.988 1.00 5.89 ? 826 HOH A O 1 HETATM 8709 O O . HOH BA 10 . ? 54.984 -23.540 -21.679 1.00 43.28 ? 827 HOH A O 1 HETATM 8710 O O . HOH BA 10 . ? 71.026 13.366 -44.301 1.00 33.13 ? 828 HOH A O 1 HETATM 8711 O O . HOH BA 10 . ? 67.504 5.551 -30.813 1.00 9.92 ? 829 HOH A O 1 HETATM 8712 O O . HOH BA 10 . ? 57.859 -1.752 -37.922 1.00 8.23 ? 830 HOH A O 1 HETATM 8713 O O . HOH BA 10 . ? 77.777 -7.699 -31.856 1.00 7.75 ? 831 HOH A O 1 HETATM 8714 O O . HOH BA 10 . ? 51.281 -10.859 -6.780 1.00 10.07 ? 832 HOH A O 1 HETATM 8715 O O . HOH BA 10 . ? 69.285 7.568 -27.449 1.00 9.94 ? 833 HOH A O 1 HETATM 8716 O O . HOH BA 10 . ? 85.538 -22.939 -36.088 1.00 10.53 ? 834 HOH A O 1 HETATM 8717 O O . HOH BA 10 . ? 71.138 -9.073 -34.312 1.00 7.31 ? 835 HOH A O 1 HETATM 8718 O O . HOH BA 10 . ? 69.572 -15.732 -31.438 1.00 10.89 ? 836 HOH A O 1 HETATM 8719 O O . HOH BA 10 . ? 57.217 -10.041 -15.440 1.00 9.27 ? 837 HOH A O 1 HETATM 8720 O O . HOH BA 10 . ? 81.446 -13.900 -16.390 1.00 11.69 ? 838 HOH A O 1 HETATM 8721 O O . HOH BA 10 . ? 64.285 1.136 -20.608 1.00 10.04 ? 839 HOH A O 1 HETATM 8722 O O . HOH BA 10 . ? 68.839 -5.506 -33.906 1.00 10.74 ? 840 HOH A O 1 HETATM 8723 O O . HOH BA 10 . ? 67.418 -10.975 -22.577 1.00 8.48 ? 841 HOH A O 1 HETATM 8724 O O . HOH BA 10 . ? 55.356 -0.326 -19.677 1.00 9.75 ? 842 HOH A O 1 HETATM 8725 O O . HOH BA 10 . ? 60.814 -11.663 -12.376 1.00 11.51 ? 843 HOH A O 1 HETATM 8726 O O . HOH BA 10 . ? 90.886 -20.109 -29.687 1.00 11.59 ? 844 HOH A O 1 HETATM 8727 O O . HOH BA 10 . ? 78.217 -7.990 -43.258 1.00 7.52 ? 845 HOH A O 1 HETATM 8728 O O . HOH BA 10 . ? 56.196 -4.413 -10.157 1.00 9.19 ? 846 HOH A O 1 HETATM 8729 O O . HOH BA 10 . ? 70.320 -20.655 -39.918 1.00 9.18 ? 847 HOH A O 1 HETATM 8730 O O . HOH BA 10 . ? 73.165 -7.204 -50.006 1.00 12.50 ? 848 HOH A O 1 HETATM 8731 O O . HOH BA 10 . ? 77.685 5.631 -36.825 1.00 10.66 ? 849 HOH A O 1 HETATM 8732 O O . HOH BA 10 . ? 47.881 1.290 -36.302 1.00 10.26 ? 850 HOH A O 1 HETATM 8733 O O . HOH BA 10 . ? 75.813 -7.494 -50.197 1.00 8.37 ? 851 HOH A O 1 HETATM 8734 O O . HOH BA 10 . ? 54.194 -17.772 -31.026 1.00 13.95 ? 852 HOH A O 1 HETATM 8735 O O . HOH BA 10 . ? 76.271 -5.464 -42.715 1.00 9.52 ? 853 HOH A O 1 HETATM 8736 O O . HOH BA 10 . ? 48.849 -17.385 -42.586 1.00 13.79 ? 854 HOH A O 1 HETATM 8737 O O . HOH BA 10 . ? 42.158 9.185 -25.367 1.00 13.03 ? 855 HOH A O 1 HETATM 8738 O O . HOH BA 10 . ? 49.545 -9.433 -29.538 1.00 11.30 ? 856 HOH A O 1 HETATM 8739 O O . HOH BA 10 . ? 38.890 2.175 -19.225 1.00 11.71 ? 857 HOH A O 1 HETATM 8740 O O . HOH BA 10 . ? 74.064 -5.763 -38.563 1.00 8.02 ? 858 HOH A O 1 HETATM 8741 O O . HOH BA 10 . ? 60.195 -17.072 -27.551 1.00 14.32 ? 859 HOH A O 1 HETATM 8742 O O . HOH BA 10 . ? 96.048 -17.108 -30.787 1.00 13.42 ? 860 HOH A O 1 HETATM 8743 O O . HOH BA 10 . ? 49.125 -3.010 -34.390 1.00 12.80 ? 861 HOH A O 1 HETATM 8744 O O . HOH BA 10 . ? 51.432 -8.902 -31.465 1.00 12.30 ? 862 HOH A O 1 HETATM 8745 O O . HOH BA 10 . ? 60.844 -8.395 -33.318 1.00 9.16 ? 863 HOH A O 1 HETATM 8746 O O . HOH BA 10 . ? 50.484 -9.559 -41.577 1.00 14.37 ? 864 HOH A O 1 HETATM 8747 O O . HOH BA 10 . ? 51.285 -3.411 -41.264 1.00 13.11 ? 865 HOH A O 1 HETATM 8748 O O . HOH BA 10 . ? 65.797 -20.539 -29.619 1.00 14.45 ? 866 HOH A O 1 HETATM 8749 O O . HOH BA 10 . ? 67.463 -15.235 -29.920 1.00 12.26 ? 867 HOH A O 1 HETATM 8750 O O . HOH BA 10 . ? 49.611 -0.291 -38.011 1.00 13.31 ? 868 HOH A O 1 HETATM 8751 O O . HOH BA 10 . ? 58.313 3.615 -40.560 1.00 9.81 ? 869 HOH A O 1 HETATM 8752 O O . HOH BA 10 . ? 43.261 -14.372 -40.565 1.00 10.22 ? 870 HOH A O 1 HETATM 8753 O O . HOH BA 10 . ? 99.336 -12.937 -27.477 1.00 10.84 ? 871 HOH A O 1 HETATM 8754 O O . HOH BA 10 . ? 57.025 -19.687 -41.379 1.00 14.54 ? 872 HOH A O 1 HETATM 8755 O O . HOH BA 10 . ? 57.145 3.578 -12.006 1.00 12.87 ? 873 HOH A O 1 HETATM 8756 O O . HOH BA 10 . ? 43.558 -16.668 -29.554 1.00 13.63 ? 874 HOH A O 1 HETATM 8757 O O . HOH BA 10 . ? 39.287 -12.537 -40.380 1.00 13.24 ? 875 HOH A O 1 HETATM 8758 O O . HOH BA 10 . ? 48.958 -11.276 -43.108 1.00 12.77 ? 876 HOH A O 1 HETATM 8759 O O . HOH BA 10 . ? 69.543 -16.467 -14.923 1.00 11.91 ? 877 HOH A O 1 HETATM 8760 O O . HOH BA 10 . ? 81.059 -11.886 -12.661 1.00 16.07 ? 878 HOH A O 1 HETATM 8761 O O . HOH BA 10 . ? 67.172 -7.490 -33.022 1.00 12.36 ? 879 HOH A O 1 HETATM 8762 O O . HOH BA 10 . ? 74.691 -4.040 -45.373 1.00 13.66 ? 880 HOH A O 1 HETATM 8763 O O . HOH BA 10 . ? 38.665 -3.694 -12.572 1.00 13.14 ? 881 HOH A O 1 HETATM 8764 O O . HOH BA 10 . ? 39.562 -7.619 -24.338 1.00 13.00 ? 882 HOH A O 1 HETATM 8765 O O . HOH BA 10 . ? 103.281 -4.579 -24.503 1.00 10.51 ? 883 HOH A O 1 HETATM 8766 O O . HOH BA 10 . ? 65.271 -11.704 -30.001 1.00 11.62 ? 884 HOH A O 1 HETATM 8767 O O . HOH BA 10 . ? 82.964 -15.617 -14.702 1.00 16.52 ? 885 HOH A O 1 HETATM 8768 O O . HOH BA 10 . ? 43.161 -0.741 -10.337 1.00 15.42 ? 886 HOH A O 1 HETATM 8769 O O . HOH BA 10 . ? 64.629 -20.238 -44.106 1.00 12.75 ? 887 HOH A O 1 HETATM 8770 O O . HOH BA 10 . ? 70.920 0.539 -9.981 1.00 16.53 ? 888 HOH A O 1 HETATM 8771 O O . HOH BA 10 . ? 63.542 -22.007 -37.124 1.00 16.35 ? 889 HOH A O 1 HETATM 8772 O O . HOH BA 10 . ? 50.586 -9.368 -20.816 1.00 13.03 ? 890 HOH A O 1 HETATM 8773 O O . HOH BA 10 . ? 95.485 -1.538 -27.025 1.00 13.34 ? 891 HOH A O 1 HETATM 8774 O O . HOH BA 10 . ? 87.878 4.462 -42.087 1.00 13.79 ? 892 HOH A O 1 HETATM 8775 O O . HOH BA 10 . ? 77.555 -3.293 -43.881 1.00 11.51 ? 893 HOH A O 1 HETATM 8776 O O . HOH BA 10 . ? 74.161 10.008 -15.707 1.00 13.19 ? 894 HOH A O 1 HETATM 8777 O O . HOH BA 10 . ? 59.610 3.362 -13.790 1.00 11.42 ? 895 HOH A O 1 HETATM 8778 O O . HOH BA 10 . ? 64.929 -14.843 -16.163 1.00 12.69 ? 896 HOH A O 1 HETATM 8779 O O . HOH BA 10 . ? 74.475 -1.334 -45.230 1.00 13.73 ? 897 HOH A O 1 HETATM 8780 O O . HOH BA 10 . ? 82.061 -5.330 -49.969 1.00 14.57 ? 898 HOH A O 1 HETATM 8781 O O . HOH BA 10 . ? 66.257 6.639 -39.261 1.00 12.64 ? 899 HOH A O 1 HETATM 8782 O O . HOH BA 10 . ? 71.564 -7.144 -37.705 1.00 9.77 ? 900 HOH A O 1 HETATM 8783 O O . HOH BA 10 . ? 70.193 7.963 -36.929 1.00 12.38 ? 901 HOH A O 1 HETATM 8784 O O . HOH BA 10 . ? 84.384 -26.284 -36.867 1.00 14.60 ? 902 HOH A O 1 HETATM 8785 O O . HOH BA 10 . ? 34.384 -2.561 -26.401 1.00 13.43 ? 903 HOH A O 1 HETATM 8786 O O . HOH BA 10 . ? 68.590 -16.466 -17.465 1.00 15.04 ? 904 HOH A O 1 HETATM 8787 O O . HOH BA 10 . ? 79.931 -1.886 -43.735 1.00 14.45 ? 905 HOH A O 1 HETATM 8788 O O . HOH BA 10 . ? 73.725 -9.404 -19.697 1.00 14.31 ? 906 HOH A O 1 HETATM 8789 O O . HOH BA 10 . ? 56.942 5.586 -37.768 1.00 16.72 ? 907 HOH A O 1 HETATM 8790 O O . HOH BA 10 . ? 95.317 -5.614 -30.114 1.00 14.37 ? 908 HOH A O 1 HETATM 8791 O O . HOH BA 10 . ? 102.397 -6.913 -25.770 1.00 11.46 ? 909 HOH A O 1 HETATM 8792 O O . HOH BA 10 . ? 65.120 -12.965 -48.618 1.00 22.35 ? 910 HOH A O 1 HETATM 8793 O O . HOH BA 10 . ? 46.436 2.538 -32.496 1.00 12.65 ? 911 HOH A O 1 HETATM 8794 O O . HOH BA 10 . ? 51.260 9.675 -16.046 1.00 15.28 ? 912 HOH A O 1 HETATM 8795 O O . HOH BA 10 . ? 55.657 6.467 -40.039 1.00 16.69 ? 913 HOH A O 1 HETATM 8796 O O . HOH BA 10 . ? 79.442 -28.628 -42.307 1.00 21.10 ? 914 HOH A O 1 HETATM 8797 O O . HOH BA 10 . ? 79.133 -12.381 -62.219 1.00 16.14 ? 915 HOH A O 1 HETATM 8798 O O . HOH BA 10 . ? 73.131 12.633 -32.502 1.00 14.61 ? 916 HOH A O 1 HETATM 8799 O O . HOH BA 10 . ? 71.550 -0.456 -48.536 1.00 15.86 ? 917 HOH A O 1 HETATM 8800 O O . HOH BA 10 . ? 43.784 -12.780 -23.898 1.00 13.67 ? 918 HOH A O 1 HETATM 8801 O O . HOH BA 10 . ? 78.629 -23.972 -23.232 1.00 14.91 ? 919 HOH A O 1 HETATM 8802 O O . HOH BA 10 . ? 61.929 -2.956 -27.869 1.00 17.62 ? 920 HOH A O 1 HETATM 8803 O O . HOH BA 10 . ? 82.986 -1.690 -47.893 1.00 15.98 ? 921 HOH A O 1 HETATM 8804 O O . HOH BA 10 . ? 79.211 -23.146 -25.677 1.00 14.44 ? 922 HOH A O 1 HETATM 8805 O O . HOH BA 10 . ? 75.950 0.845 -44.190 1.00 11.35 ? 923 HOH A O 1 HETATM 8806 O O . HOH BA 10 . ? 74.359 -25.033 -43.014 1.00 14.98 ? 924 HOH A O 1 HETATM 8807 O O . HOH BA 10 . ? 57.346 -17.278 -24.062 1.00 17.00 ? 925 HOH A O 1 HETATM 8808 O O . HOH BA 10 . ? 77.580 10.745 -20.222 1.00 18.29 ? 926 HOH A O 1 HETATM 8809 O O . HOH BA 10 . ? 64.323 -6.590 -47.607 1.00 13.74 ? 927 HOH A O 1 HETATM 8810 O O . HOH BA 10 . ? 86.911 -26.354 -35.786 1.00 18.31 ? 928 HOH A O 1 HETATM 8811 O O . HOH BA 10 . ? 44.598 5.870 -13.373 1.00 15.39 ? 929 HOH A O 1 HETATM 8812 O O . HOH BA 10 . ? 49.146 16.288 -24.781 1.00 21.13 ? 930 HOH A O 1 HETATM 8813 O O . HOH BA 10 . ? 46.900 13.407 -26.460 1.00 16.18 ? 931 HOH A O 1 HETATM 8814 O O . HOH BA 10 . ? 41.440 -9.166 -14.195 1.00 13.21 ? 932 HOH A O 1 HETATM 8815 O O . HOH BA 10 . ? 41.535 -10.741 -16.562 1.00 19.21 ? 933 HOH A O 1 HETATM 8816 O O . HOH BA 10 . ? 82.216 1.626 -42.773 1.00 16.75 ? 934 HOH A O 1 HETATM 8817 O O . HOH BA 10 . ? 34.358 -15.287 -32.425 1.00 16.48 ? 935 HOH A O 1 HETATM 8818 O O . HOH BA 10 . ? 99.798 -5.019 -28.610 1.00 16.86 ? 936 HOH A O 1 HETATM 8819 O O . HOH BA 10 . ? 98.646 -7.738 -32.363 1.00 20.01 ? 937 HOH A O 1 HETATM 8820 O O . HOH BA 10 . ? 36.142 -4.749 -22.578 1.00 14.65 ? 938 HOH A O 1 HETATM 8821 O O . HOH BA 10 . ? 102.395 -12.435 -37.084 1.00 17.98 ? 939 HOH A O 1 HETATM 8822 O O . HOH BA 10 . ? 67.391 4.101 -14.522 1.00 21.28 ? 940 HOH A O 1 HETATM 8823 O O . HOH BA 10 . ? 70.131 -16.212 -57.378 1.00 20.43 ? 941 HOH A O 1 HETATM 8824 O O . HOH BA 10 . ? 54.739 -11.805 -45.696 1.00 16.75 ? 942 HOH A O 1 HETATM 8825 O O . HOH BA 10 . ? 76.213 11.402 -14.682 1.00 22.13 ? 943 HOH A O 1 HETATM 8826 O O . HOH BA 10 . ? 45.700 -1.966 -10.156 1.00 14.53 ? 944 HOH A O 1 HETATM 8827 O O . HOH BA 10 . ? 54.913 6.835 -10.022 1.00 24.13 ? 945 HOH A O 1 HETATM 8828 O O . HOH BA 10 . ? 77.586 -26.832 -25.918 1.00 17.02 ? 946 HOH A O 1 HETATM 8829 O O . HOH BA 10 . ? 39.392 1.771 -9.235 1.00 16.22 ? 947 HOH A O 1 HETATM 8830 O O . HOH BA 10 . ? 54.388 -14.576 -45.961 1.00 18.82 ? 948 HOH A O 1 HETATM 8831 O O . HOH BA 10 . ? 33.903 -8.812 -37.920 1.00 22.98 ? 949 HOH A O 1 HETATM 8832 O O . HOH BA 10 . ? 72.087 -15.720 -30.040 1.00 14.56 ? 950 HOH A O 1 HETATM 8833 O O . HOH BA 10 . ? 68.234 -0.511 -46.587 1.00 22.51 ? 951 HOH A O 1 HETATM 8834 O O . HOH BA 10 . ? 56.654 -21.906 -38.984 1.00 16.28 ? 952 HOH A O 1 HETATM 8835 O O . HOH BA 10 . ? 44.719 -13.743 -15.080 1.00 21.91 ? 953 HOH A O 1 HETATM 8836 O O . HOH BA 10 . ? 41.756 -15.543 -27.922 1.00 15.91 ? 954 HOH A O 1 HETATM 8837 O O . HOH BA 10 . ? 69.665 7.278 -39.804 1.00 13.03 ? 955 HOH A O 1 HETATM 8838 O O . HOH BA 10 . ? 39.299 -5.834 -37.833 1.00 14.13 ? 956 HOH A O 1 HETATM 8839 O O . HOH BA 10 . ? 54.344 -19.240 -26.840 1.00 22.98 ? 957 HOH A O 1 HETATM 8840 O O . HOH BA 10 . ? 62.791 9.737 -27.172 1.00 17.52 ? 958 HOH A O 1 HETATM 8841 O O . HOH BA 10 . ? 96.728 -3.912 -28.228 1.00 17.27 ? 959 HOH A O 1 HETATM 8842 O O . HOH BA 10 . ? 61.048 -15.322 -24.576 1.00 14.67 ? 960 HOH A O 1 HETATM 8843 O O . HOH BA 10 . ? 45.084 -14.077 -10.987 1.00 17.40 ? 961 HOH A O 1 HETATM 8844 O O . HOH BA 10 . ? 71.970 10.450 -33.908 1.00 14.63 ? 962 HOH A O 1 HETATM 8845 O O . HOH BA 10 . ? 41.416 0.713 -29.760 1.00 14.77 ? 963 HOH A O 1 HETATM 8846 O O . HOH BA 10 . ? 62.997 -16.766 -15.996 1.00 15.25 ? 964 HOH A O 1 HETATM 8847 O O . HOH BA 10 . ? 98.520 -16.880 -28.673 1.00 19.13 ? 965 HOH A O 1 HETATM 8848 O O . HOH BA 10 . ? 46.959 0.101 -34.065 1.00 16.27 ? 966 HOH A O 1 HETATM 8849 O O . HOH BA 10 . ? 36.349 2.451 -9.666 1.00 20.99 ? 967 HOH A O 1 HETATM 8850 O O . HOH BA 10 . ? 59.013 16.597 -35.265 1.00 23.86 ? 968 HOH A O 1 HETATM 8851 O O . HOH BA 10 . ? 88.075 -27.521 -41.410 1.00 15.18 ? 969 HOH A O 1 HETATM 8852 O O . HOH BA 10 . ? 46.559 -17.830 -27.862 1.00 21.64 ? 970 HOH A O 1 HETATM 8853 O O . HOH BA 10 . ? 86.213 -15.908 -48.566 1.00 21.28 ? 971 HOH A O 1 HETATM 8854 O O . HOH BA 10 . ? 100.378 -14.897 -30.425 1.00 19.45 ? 972 HOH A O 1 HETATM 8855 O O . HOH BA 10 . ? 77.475 3.394 -14.087 1.00 17.21 ? 973 HOH A O 1 HETATM 8856 O O . HOH BA 10 . ? 64.780 13.974 -39.902 1.00 20.69 ? 974 HOH A O 1 HETATM 8857 O O . HOH BA 10 . ? 76.676 3.084 -45.845 1.00 18.44 ? 975 HOH A O 1 HETATM 8858 O O . HOH BA 10 . ? 45.245 -18.941 -35.570 1.00 17.50 ? 976 HOH A O 1 HETATM 8859 O O . HOH BA 10 . ? 65.555 -2.336 -47.445 1.00 18.49 ? 977 HOH A O 1 HETATM 8860 O O . HOH BA 10 . ? 49.673 -23.802 -36.218 1.00 24.17 ? 978 HOH A O 1 HETATM 8861 O O . HOH BA 10 . ? 82.718 -22.528 -56.614 1.00 20.69 ? 979 HOH A O 1 HETATM 8862 O O . HOH BA 10 . ? 96.446 -22.304 -25.702 1.00 19.57 ? 980 HOH A O 1 HETATM 8863 O O . HOH BA 10 . ? 37.576 0.267 -30.551 1.00 16.30 ? 981 HOH A O 1 HETATM 8864 O O . HOH BA 10 . ? 55.526 -16.112 -12.229 1.00 23.11 ? 982 HOH A O 1 HETATM 8865 O O . HOH BA 10 . ? 82.452 -8.449 -50.094 1.00 19.91 ? 983 HOH A O 1 HETATM 8866 O O . HOH BA 10 . ? 80.629 4.351 -41.210 1.00 16.36 ? 984 HOH A O 1 HETATM 8867 O O . HOH BA 10 . ? 41.739 -11.317 -22.649 1.00 18.29 ? 985 HOH A O 1 HETATM 8868 O O . HOH BA 10 . ? 78.099 -6.932 -57.987 1.00 19.98 ? 986 HOH A O 1 HETATM 8869 O O . HOH BA 10 . ? 44.296 8.019 -36.459 1.00 21.89 ? 987 HOH A O 1 HETATM 8870 O O . HOH BA 10 . ? 73.192 -22.340 -59.461 1.00 16.57 ? 988 HOH A O 1 HETATM 8871 O O . HOH BA 10 . ? 96.140 -1.452 -48.873 1.00 22.08 ? 989 HOH A O 1 HETATM 8872 O O . HOH BA 10 . ? 50.250 -22.748 -39.011 1.00 25.74 ? 990 HOH A O 1 HETATM 8873 O O . HOH BA 10 . ? 34.688 -2.446 -34.270 1.00 20.04 ? 991 HOH A O 1 HETATM 8874 O O . HOH BA 10 . ? 48.838 10.886 -15.670 1.00 22.45 ? 992 HOH A O 1 HETATM 8875 O O . HOH BA 10 . ? 84.342 -17.063 -52.148 1.00 17.53 ? 993 HOH A O 1 HETATM 8876 O O . HOH BA 10 . ? 50.711 -14.642 -43.193 1.00 18.09 ? 994 HOH A O 1 HETATM 8877 O O . HOH BA 10 . ? 91.496 2.649 -21.504 1.00 16.48 ? 995 HOH A O 1 HETATM 8878 O O . HOH BA 10 . ? 63.921 11.983 -29.254 1.00 20.88 ? 996 HOH A O 1 HETATM 8879 O O . HOH BA 10 . ? 68.037 -11.630 -11.255 1.00 22.48 ? 997 HOH A O 1 HETATM 8880 O O . HOH BA 10 . ? 99.606 -18.264 -30.905 1.00 18.29 ? 998 HOH A O 1 HETATM 8881 O O . HOH BA 10 . ? 83.796 -15.610 -59.437 1.00 21.32 ? 999 HOH A O 1 HETATM 8882 O O . HOH BA 10 . ? 59.960 15.279 -32.953 1.00 21.61 ? 1000 HOH A O 1 HETATM 8883 O O . HOH BA 10 . ? 36.704 -0.982 -15.373 1.00 20.43 ? 1001 HOH A O 1 HETATM 8884 O O . HOH BA 10 . ? 89.066 1.474 -20.890 1.00 16.21 ? 1002 HOH A O 1 HETATM 8885 O O . HOH BA 10 . ? 82.518 1.175 -17.856 1.00 22.86 ? 1003 HOH A O 1 HETATM 8886 O O . HOH BA 10 . ? 45.767 8.258 -13.289 1.00 19.88 ? 1004 HOH A O 1 HETATM 8887 O O . HOH BA 10 . ? 53.985 8.621 -40.351 1.00 21.05 ? 1005 HOH A O 1 HETATM 8888 O O . HOH BA 10 . ? 89.005 -24.534 -34.936 1.00 21.88 ? 1006 HOH A O 1 HETATM 8889 O O . HOH BA 10 . ? 87.192 -22.652 -33.847 1.00 18.62 ? 1007 HOH A O 1 HETATM 8890 O O . HOH BA 10 . ? 94.503 -4.756 -39.608 1.00 17.73 ? 1008 HOH A O 1 HETATM 8891 O O . HOH BA 10 . ? 66.472 -9.500 -10.270 1.00 15.34 ? 1009 HOH A O 1 HETATM 8892 O O . HOH BA 10 . ? 62.297 0.688 -9.448 1.00 21.54 ? 1010 HOH A O 1 HETATM 8893 O O . HOH BA 10 . ? 83.643 8.215 -35.104 1.00 18.17 ? 1011 HOH A O 1 HETATM 8894 O O . HOH BA 10 . ? 57.124 -16.059 -48.562 1.00 25.54 ? 1012 HOH A O 1 HETATM 8895 O O . HOH BA 10 . ? 95.040 1.982 -24.226 1.00 27.84 ? 1013 HOH A O 1 HETATM 8896 O O . HOH BA 10 . ? 72.129 4.781 -9.512 1.00 22.98 ? 1014 HOH A O 1 HETATM 8897 O O . HOH BA 10 . ? 56.815 -0.005 -45.669 1.00 14.60 ? 1015 HOH A O 1 HETATM 8898 O O . HOH BA 10 . ? 42.848 13.460 -27.255 1.00 22.07 ? 1016 HOH A O 1 HETATM 8899 O O . HOH BA 10 . ? 49.331 -14.167 -15.600 1.00 19.52 ? 1017 HOH A O 1 HETATM 8900 O O . HOH BA 10 . ? 60.608 -17.642 -23.163 1.00 16.58 ? 1018 HOH A O 1 HETATM 8901 O O . HOH BA 10 . ? 76.501 -3.886 -56.120 1.00 20.78 ? 1019 HOH A O 1 HETATM 8902 O O . HOH BA 10 . ? 67.434 11.799 -21.195 1.00 21.27 ? 1020 HOH A O 1 HETATM 8903 O O . HOH BA 10 . ? 79.452 6.039 -39.432 1.00 18.42 ? 1021 HOH A O 1 HETATM 8904 O O . HOH BA 10 . ? 98.811 -6.623 -19.444 1.00 32.91 ? 1022 HOH A O 1 HETATM 8905 O O . HOH BA 10 . ? 37.532 -11.538 -25.206 1.00 22.72 ? 1023 HOH A O 1 HETATM 8906 O O . HOH BA 10 . ? 76.100 -27.750 -39.760 1.00 25.57 ? 1024 HOH A O 1 HETATM 8907 O O . HOH BA 10 . ? 76.169 14.275 -34.943 1.00 21.17 ? 1025 HOH A O 1 HETATM 8908 O O . HOH BA 10 . ? 39.036 1.890 -29.016 1.00 21.58 ? 1026 HOH A O 1 HETATM 8909 O O . HOH BA 10 . ? 71.926 2.867 -45.221 1.00 21.94 ? 1027 HOH A O 1 HETATM 8910 O O . HOH BA 10 . ? 66.536 8.368 -44.905 1.00 22.00 ? 1028 HOH A O 1 HETATM 8911 O O . HOH BA 10 . ? 66.541 -24.371 -18.964 1.00 22.31 ? 1029 HOH A O 1 HETATM 8912 O O . HOH BA 10 . ? 87.061 -7.299 -50.269 1.00 23.54 ? 1030 HOH A O 1 HETATM 8913 O O . HOH BA 10 . ? 92.959 -24.251 -27.981 1.00 26.16 ? 1031 HOH A O 1 HETATM 8914 O O . HOH BA 10 . ? 32.095 -7.531 -34.306 1.00 21.02 ? 1032 HOH A O 1 HETATM 8915 O O . HOH BA 10 . ? 76.752 -17.874 -10.631 1.00 20.87 ? 1033 HOH A O 1 HETATM 8916 O O . HOH BA 10 . ? 99.437 -6.878 -22.099 1.00 21.01 ? 1034 HOH A O 1 HETATM 8917 O O . HOH BA 10 . ? 84.553 2.084 -44.222 1.00 21.21 ? 1035 HOH A O 1 HETATM 8918 O O . HOH BA 10 . ? 98.588 -11.515 -25.125 1.00 18.92 ? 1036 HOH A O 1 HETATM 8919 O O . HOH BA 10 . ? 81.661 -11.120 -54.206 1.00 25.22 ? 1037 HOH A O 1 HETATM 8920 O O . HOH BA 10 . ? 79.989 2.109 -17.358 1.00 16.50 ? 1038 HOH A O 1 HETATM 8921 O O . HOH BA 10 . ? 40.032 -1.793 -36.521 1.00 16.85 ? 1039 HOH A O 1 HETATM 8922 O O . HOH BA 10 . ? 70.011 3.113 -9.829 1.00 22.95 ? 1040 HOH A O 1 HETATM 8923 O O . HOH BA 10 . ? 85.355 11.031 -29.316 1.00 25.47 ? 1041 HOH A O 1 HETATM 8924 O O . HOH BA 10 . ? 52.827 -11.658 -43.820 1.00 17.60 ? 1042 HOH A O 1 HETATM 8925 O O . HOH BA 10 . ? 35.496 -15.295 -28.597 1.00 24.91 ? 1043 HOH A O 1 HETATM 8926 O O . HOH BA 10 . ? 75.950 11.812 -40.563 1.00 19.59 ? 1044 HOH A O 1 HETATM 8927 O O . HOH BA 10 . ? 49.129 -20.029 -42.829 1.00 18.22 ? 1045 HOH A O 1 HETATM 8928 O O . HOH BA 10 . ? 57.298 -6.853 -22.388 1.00 18.13 ? 1046 HOH A O 1 HETATM 8929 O O . HOH BA 10 . ? 36.324 1.972 -18.847 1.00 24.38 ? 1047 HOH A O 1 HETATM 8930 O O . HOH BA 10 . ? 99.708 -2.697 -27.095 1.00 21.98 ? 1048 HOH A O 1 HETATM 8931 O O . HOH BA 10 . ? 93.952 -24.873 -38.785 1.00 32.78 ? 1049 HOH A O 1 HETATM 8932 O O . HOH BA 10 . ? 43.716 -16.893 -34.354 1.00 20.76 ? 1050 HOH A O 1 HETATM 8933 O O . HOH BA 10 . ? 98.207 -9.870 -21.578 1.00 27.31 ? 1051 HOH A O 1 HETATM 8934 O O . HOH BA 10 . ? 94.489 -8.680 -18.331 1.00 20.50 ? 1052 HOH A O 1 HETATM 8935 O O . HOH BA 10 . ? 76.900 -12.516 -60.688 1.00 29.26 ? 1053 HOH A O 1 HETATM 8936 O O . HOH BA 10 . ? 45.795 3.964 -11.811 1.00 25.58 ? 1054 HOH A O 1 HETATM 8937 O O . HOH BA 10 . ? 101.115 -3.060 -42.455 1.00 25.75 ? 1055 HOH A O 1 HETATM 8938 O O . HOH BA 10 . ? 72.819 -7.466 -10.963 1.00 18.16 ? 1056 HOH A O 1 HETATM 8939 O O . HOH BA 10 . ? 35.484 5.229 -29.381 1.00 20.51 ? 1057 HOH A O 1 HETATM 8940 O O . HOH BA 10 . ? 65.329 5.747 -14.559 1.00 19.61 ? 1058 HOH A O 1 HETATM 8941 O O . HOH BA 10 . ? 95.522 -16.284 -45.396 1.00 26.26 ? 1059 HOH A O 1 HETATM 8942 O O . HOH BA 10 . ? 82.560 -27.779 -35.503 1.00 20.03 ? 1060 HOH A O 1 HETATM 8943 O O . HOH BA 10 . ? 83.523 10.821 -32.994 1.00 32.52 ? 1061 HOH A O 1 HETATM 8944 O O . HOH BA 10 . ? 42.930 -7.779 -45.208 1.00 23.00 ? 1062 HOH A O 1 HETATM 8945 O O . HOH BA 10 . ? 60.805 -5.394 -5.377 1.00 21.52 ? 1063 HOH A O 1 HETATM 8946 O O . HOH BA 10 . ? 86.574 2.349 -16.892 1.00 24.01 ? 1064 HOH A O 1 HETATM 8947 O O . HOH BA 10 . ? 69.543 -23.687 -48.627 1.00 21.91 ? 1065 HOH A O 1 HETATM 8948 O O . HOH BA 10 . ? 37.005 -0.722 -34.315 1.00 19.37 ? 1066 HOH A O 1 HETATM 8949 O O . HOH BA 10 . ? 95.662 -19.333 -21.962 1.00 25.58 ? 1067 HOH A O 1 HETATM 8950 O O . HOH BA 10 . ? 70.481 -12.734 -54.043 1.00 22.34 ? 1068 HOH A O 1 HETATM 8951 O O . HOH BA 10 . ? 57.320 -17.615 -15.607 1.00 19.76 ? 1069 HOH A O 1 HETATM 8952 O O . HOH BA 10 . ? 43.159 -13.404 -12.855 1.00 16.75 ? 1070 HOH A O 1 HETATM 8953 O O . HOH BA 10 . ? 28.997 -5.626 -30.858 1.00 16.22 ? 1071 HOH A O 1 HETATM 8954 O O . HOH BA 10 . ? 37.900 -6.818 -22.425 1.00 17.45 ? 1072 HOH A O 1 HETATM 8955 O O . HOH BA 10 . ? 58.273 6.188 -40.948 1.00 14.06 ? 1073 HOH A O 1 HETATM 8956 O O . HOH BA 10 . ? 78.618 0.522 -43.368 1.00 14.34 ? 1074 HOH A O 1 HETATM 8957 O O . HOH BA 10 . ? 52.800 -9.045 -42.859 1.00 16.72 ? 1075 HOH A O 1 HETATM 8958 O O . HOH BA 10 . ? 49.532 -15.424 -10.067 1.00 17.11 ? 1076 HOH A O 1 HETATM 8959 O O . HOH BA 10 . ? 48.097 20.356 -31.403 1.00 18.64 ? 1077 HOH A O 1 HETATM 8960 O O . HOH BA 10 . ? 50.572 -12.200 -45.008 1.00 17.52 ? 1078 HOH A O 1 HETATM 8961 O O . HOH BA 10 . ? 39.190 -10.228 -23.536 1.00 17.40 ? 1079 HOH A O 1 HETATM 8962 O O . HOH BA 10 . ? 102.539 -9.007 -24.008 1.00 16.88 ? 1080 HOH A O 1 HETATM 8963 O O . HOH BA 10 . ? 41.290 -4.003 -37.981 1.00 19.85 ? 1081 HOH A O 1 HETATM 8964 O O . HOH BA 10 . ? 87.697 -28.900 -39.266 1.00 18.11 ? 1082 HOH A O 1 HETATM 8965 O O . HOH BA 10 . ? 54.932 15.991 -21.681 1.00 17.79 ? 1083 HOH A O 1 HETATM 8966 O O . HOH BA 10 . ? 63.315 5.806 -45.625 1.00 21.51 ? 1084 HOH A O 1 HETATM 8967 O O . HOH BA 10 . ? 42.496 -14.960 -25.097 1.00 19.06 ? 1085 HOH A O 1 HETATM 8968 O O . HOH BA 10 . ? 100.087 -6.135 -36.206 1.00 19.68 ? 1086 HOH A O 1 HETATM 8969 O O . HOH BA 10 . ? 45.322 -14.018 -21.979 1.00 20.39 ? 1087 HOH A O 1 HETATM 8970 O O . HOH BA 10 . ? 70.259 -21.941 -13.173 1.00 31.04 ? 1088 HOH A O 1 HETATM 8971 O O . HOH BA 10 . ? 35.225 -15.075 -34.941 1.00 22.53 ? 1089 HOH A O 1 HETATM 8972 O O . HOH BA 10 . ? 37.846 -14.388 -25.789 1.00 19.65 ? 1090 HOH A O 1 HETATM 8973 O O . HOH BA 10 . ? 37.774 -4.031 -36.553 1.00 20.56 ? 1091 HOH A O 1 HETATM 8974 O O . HOH BA 10 . ? 80.589 -20.524 -57.345 1.00 23.02 ? 1092 HOH A O 1 HETATM 8975 O O . HOH BA 10 . ? 71.172 0.650 -46.162 1.00 22.16 ? 1093 HOH A O 1 HETATM 8976 O O . HOH BA 10 . ? 70.531 -22.156 -59.823 1.00 21.80 ? 1094 HOH A O 1 HETATM 8977 O O . HOH BA 10 . ? 83.843 -14.429 -51.949 1.00 20.89 ? 1095 HOH A O 1 HETATM 8978 O O . HOH BA 10 . ? 65.922 -23.217 -29.495 1.00 25.19 ? 1096 HOH A O 1 HETATM 8979 O O . HOH BA 10 . ? 80.065 9.807 -38.573 1.00 23.54 ? 1097 HOH A O 1 HETATM 8980 O O . HOH BA 10 . ? 33.379 -5.301 -33.346 1.00 21.25 ? 1098 HOH A O 1 HETATM 8981 O O . HOH BA 10 . ? 60.063 1.857 -8.446 1.00 23.53 ? 1099 HOH A O 1 HETATM 8982 O O . HOH BA 10 . ? 35.452 -4.672 -35.752 1.00 20.42 ? 1100 HOH A O 1 HETATM 8983 O O . HOH BA 10 . ? 87.316 -24.421 -49.778 1.00 20.60 ? 1101 HOH A O 1 HETATM 8984 O O . HOH BA 10 . ? 89.025 1.822 -18.251 1.00 27.63 ? 1102 HOH A O 1 HETATM 8985 O O . HOH BA 10 . ? 62.420 -19.497 -45.370 1.00 21.67 ? 1103 HOH A O 1 HETATM 8986 O O . HOH BA 10 . ? 85.500 -16.743 -15.224 1.00 21.84 ? 1104 HOH A O 1 HETATM 8987 O O . HOH BA 10 . ? 64.319 14.971 -35.294 1.00 22.57 ? 1105 HOH A O 1 HETATM 8988 O O . HOH BA 10 . ? 93.678 -2.378 -18.878 1.00 23.10 ? 1106 HOH A O 1 HETATM 8989 O O . HOH BA 10 . ? 72.674 1.164 -50.610 1.00 26.63 ? 1107 HOH A O 1 HETATM 8990 O O . HOH BA 10 . ? 100.735 -0.197 -42.221 1.00 19.95 ? 1108 HOH A O 1 HETATM 8991 O O . HOH BA 10 . ? 37.375 -6.413 -39.512 1.00 23.44 ? 1109 HOH A O 1 HETATM 8992 O O . HOH BA 10 . ? 59.672 -2.481 -25.917 1.00 21.97 ? 1110 HOH A O 1 HETATM 8993 O O . HOH BA 10 . ? 94.174 -19.733 -36.141 1.00 17.43 ? 1111 HOH A O 1 HETATM 8994 O O . HOH BA 10 . ? 69.848 12.453 -19.848 1.00 23.58 ? 1112 HOH A O 1 HETATM 8995 O O . HOH BA 10 . ? 51.012 -16.658 -13.372 1.00 25.23 ? 1113 HOH A O 1 HETATM 8996 O O . HOH BA 10 . ? 87.156 -18.292 -52.411 1.00 25.20 ? 1114 HOH A O 1 HETATM 8997 O O . HOH BA 10 . ? 87.549 -12.686 -16.130 1.00 19.81 ? 1115 HOH A O 1 HETATM 8998 O O . HOH BA 10 . ? 51.797 -24.847 -33.112 1.00 27.90 ? 1116 HOH A O 1 HETATM 8999 O O . HOH BA 10 . ? 74.559 11.284 -21.865 1.00 20.08 ? 1117 HOH A O 1 HETATM 9000 O O . HOH BA 10 . ? 39.544 5.454 -12.584 1.00 24.83 ? 1118 HOH A O 1 HETATM 9001 O O . HOH BA 10 . ? 39.503 -4.585 -17.830 1.00 25.82 ? 1119 HOH A O 1 HETATM 9002 O O . HOH BA 10 . ? 84.703 9.032 -20.084 1.00 22.12 ? 1120 HOH A O 1 HETATM 9003 O O . HOH BA 10 . ? 81.553 -27.578 -50.098 1.00 21.05 ? 1121 HOH A O 1 HETATM 9004 O O . HOH BA 10 . ? 90.722 -22.399 -28.322 1.00 25.49 ? 1122 HOH A O 1 HETATM 9005 O O . HOH BA 10 . ? 42.512 -3.377 -40.232 1.00 23.66 ? 1123 HOH A O 1 HETATM 9006 O O . HOH BA 10 . ? 90.400 -29.511 -39.964 1.00 28.32 ? 1124 HOH A O 1 HETATM 9007 O O . HOH BA 10 . ? 49.625 -16.428 -22.953 1.00 21.59 ? 1125 HOH A O 1 HETATM 9008 O O . HOH BA 10 . ? 67.638 14.049 -40.216 1.00 23.92 ? 1126 HOH A O 1 HETATM 9009 O O . HOH BA 10 . ? 43.969 12.185 -19.808 1.00 24.02 ? 1127 HOH A O 1 HETATM 9010 O O . HOH BA 10 . ? 45.328 20.650 -30.897 1.00 26.76 ? 1128 HOH A O 1 HETATM 9011 O O . HOH BA 10 . ? 86.811 8.069 -41.472 1.00 24.51 ? 1129 HOH A O 1 HETATM 9012 O O . HOH BA 10 . ? 52.220 -1.852 -43.296 1.00 24.43 ? 1130 HOH A O 1 HETATM 9013 O O . HOH BA 10 . ? 93.610 5.019 -46.159 1.00 27.85 ? 1131 HOH A O 1 HETATM 9014 O O . HOH BA 10 . ? 55.067 -8.399 -49.496 1.00 21.18 ? 1132 HOH A O 1 HETATM 9015 O O . HOH BA 10 . ? 93.859 -19.343 -38.832 1.00 20.97 ? 1133 HOH A O 1 HETATM 9016 O O . HOH BA 10 . ? 85.185 -28.506 -38.418 1.00 36.10 ? 1134 HOH A O 1 HETATM 9017 O O . HOH BA 10 . ? 76.296 -10.286 -59.577 1.00 24.36 ? 1135 HOH A O 1 HETATM 9018 O O . HOH BA 10 . ? 54.519 -12.331 -6.143 1.00 35.17 ? 1136 HOH A O 1 HETATM 9019 O O . HOH BA 10 . ? 91.501 -27.154 -25.011 1.00 30.40 ? 1137 HOH A O 1 HETATM 9020 O O . HOH BA 10 . ? 59.653 -22.228 -35.993 1.00 21.11 ? 1138 HOH A O 1 HETATM 9021 O O . HOH BA 10 . ? 103.289 -5.214 -20.687 1.00 23.00 ? 1139 HOH A O 1 HETATM 9022 O O . HOH BA 10 . ? 54.924 -20.029 -29.494 1.00 22.92 ? 1140 HOH A O 1 HETATM 9023 O O . HOH BA 10 . ? 85.220 -28.886 -44.150 1.00 25.30 ? 1141 HOH A O 1 HETATM 9024 O O . HOH BA 10 . ? 75.518 -21.988 -61.259 1.00 28.00 ? 1142 HOH A O 1 HETATM 9025 O O . HOH BA 10 . ? 37.608 -8.902 -40.771 1.00 20.45 ? 1143 HOH A O 1 HETATM 9026 O O . HOH BA 10 . ? 72.186 -26.490 -21.052 1.00 26.95 ? 1144 HOH A O 1 HETATM 9027 O O . HOH BA 10 . ? 83.139 -19.584 -13.972 1.00 27.48 ? 1145 HOH A O 1 HETATM 9028 O O . HOH BA 10 . ? 83.364 -12.829 -14.036 1.00 24.01 ? 1146 HOH A O 1 HETATM 9029 O O . HOH BA 10 . ? 38.355 4.426 -28.972 1.00 26.02 ? 1147 HOH A O 1 HETATM 9030 O O . HOH BA 10 . ? 79.833 13.580 -36.088 1.00 24.86 ? 1148 HOH A O 1 HETATM 9031 O O . HOH BA 10 . ? 68.251 -23.922 -30.621 1.00 24.40 ? 1149 HOH A O 1 HETATM 9032 O O . HOH BA 10 . ? 59.861 2.374 -46.359 1.00 23.46 ? 1150 HOH A O 1 HETATM 9033 O O . HOH BA 10 . ? 70.200 -17.724 -47.582 1.00 19.75 ? 1151 HOH A O 1 HETATM 9034 O O . HOH BA 10 . ? 90.215 -16.760 -49.025 1.00 22.25 ? 1152 HOH A O 1 HETATM 9035 O O . HOH BA 10 . ? 46.484 16.196 -24.628 1.00 20.23 ? 1153 HOH A O 1 HETATM 9036 O O . HOH BA 10 . ? 57.587 10.336 -15.254 1.00 27.23 ? 1154 HOH A O 1 HETATM 9037 O O . HOH BA 10 . ? 70.869 12.590 -41.416 1.00 27.54 ? 1155 HOH A O 1 HETATM 9038 O O . HOH BA 10 . ? 63.504 -18.731 -26.400 1.00 21.87 ? 1156 HOH A O 1 HETATM 9039 O O . HOH BA 10 . ? 81.708 -0.963 -50.024 1.00 26.62 ? 1157 HOH A O 1 HETATM 9040 O O . HOH BA 10 . ? 32.919 -16.249 -28.683 1.00 22.51 ? 1158 HOH A O 1 HETATM 9041 O O . HOH BA 10 . ? 42.154 5.606 -11.522 1.00 25.93 ? 1159 HOH A O 1 HETATM 9042 O O . HOH BA 10 . ? 102.010 -7.695 -21.670 1.00 26.93 ? 1160 HOH A O 1 HETATM 9043 O O . HOH BA 10 . ? 56.983 10.559 -12.543 1.00 29.28 ? 1161 HOH A O 1 HETATM 9044 O O . HOH BA 10 . ? 78.426 1.435 -11.165 1.00 20.27 ? 1162 HOH A O 1 HETATM 9045 O O . HOH BA 10 . ? 101.753 -17.511 -32.483 1.00 32.03 ? 1163 HOH A O 1 HETATM 9046 O O . HOH BA 10 . ? 56.640 -5.904 -24.792 1.00 23.89 ? 1164 HOH A O 1 HETATM 9047 O O . HOH BA 10 . ? 49.131 -14.023 -46.457 1.00 29.83 ? 1165 HOH A O 1 HETATM 9048 O O . HOH BA 10 . ? 72.564 12.292 -19.715 1.00 30.74 ? 1166 HOH A O 1 HETATM 9049 O O . HOH BA 10 . ? 50.218 -5.513 -42.574 1.00 26.27 ? 1167 HOH A O 1 HETATM 9050 O O . HOH BA 10 . ? 86.704 8.183 -34.703 1.00 24.21 ? 1168 HOH A O 1 HETATM 9051 O O . HOH BA 10 . ? 74.108 -9.439 -58.815 1.00 33.02 ? 1169 HOH A O 1 HETATM 9052 O O . HOH BA 10 . ? 68.774 -23.575 -33.175 1.00 24.63 ? 1170 HOH A O 1 HETATM 9053 O O . HOH BA 10 . ? 93.151 -18.727 -21.124 1.00 21.44 ? 1171 HOH A O 1 HETATM 9054 O O . HOH BA 10 . ? 79.201 1.409 -14.302 1.00 23.66 ? 1172 HOH A O 1 HETATM 9055 O O . HOH BA 10 . ? 92.220 7.224 -35.387 1.00 19.81 ? 1173 HOH A O 1 HETATM 9056 O O . HOH BA 10 . ? 66.267 -18.018 -49.381 1.00 23.31 ? 1174 HOH A O 1 HETATM 9057 O O . HOH BA 10 . ? 78.699 3.440 -43.147 1.00 23.98 ? 1175 HOH A O 1 HETATM 9058 O O . HOH BA 10 . ? 65.865 -22.753 -26.266 1.00 22.54 ? 1176 HOH A O 1 HETATM 9059 O O . HOH BA 10 . ? 79.817 -5.655 -8.091 1.00 26.67 ? 1177 HOH A O 1 HETATM 9060 O O . HOH BA 10 . ? 93.695 -27.533 -40.039 1.00 34.28 ? 1178 HOH A O 1 HETATM 9061 O O . HOH BA 10 . ? 100.237 -10.299 -23.560 1.00 26.84 ? 1179 HOH A O 1 HETATM 9062 O O . HOH BA 10 . ? 102.473 -15.426 -36.846 1.00 23.76 ? 1180 HOH A O 1 HETATM 9063 O O . HOH BA 10 . ? 82.688 -10.956 -51.804 1.00 24.68 ? 1181 HOH A O 1 HETATM 9064 O O . HOH BA 10 . ? 98.517 -19.104 -24.468 1.00 26.49 ? 1182 HOH A O 1 HETATM 9065 O O . HOH BA 10 . ? 48.166 16.431 -17.461 1.00 29.97 ? 1183 HOH A O 1 HETATM 9066 O O . HOH BA 10 . ? 101.214 -18.013 -35.053 1.00 23.24 ? 1184 HOH A O 1 HETATM 9067 O O . HOH BA 10 . ? 56.552 4.378 -7.467 1.00 27.53 ? 1185 HOH A O 1 HETATM 9068 O O . HOH BA 10 . ? 71.637 -9.701 -58.023 1.00 24.74 ? 1186 HOH A O 1 HETATM 9069 O O . HOH BA 10 . ? 43.026 10.541 -33.808 1.00 33.72 ? 1187 HOH A O 1 HETATM 9070 O O . HOH BA 10 . ? 73.915 13.896 -25.637 1.00 26.37 ? 1188 HOH A O 1 HETATM 9071 O O . HOH BA 10 . ? 42.752 -17.629 -39.867 1.00 26.46 ? 1189 HOH A O 1 HETATM 9072 O O . HOH BA 10 . ? 32.409 -0.961 -26.612 1.00 22.58 ? 1190 HOH A O 1 HETATM 9073 O O . HOH BA 10 . ? 100.074 -15.400 -26.754 1.00 24.14 ? 1191 HOH A O 1 HETATM 9074 O O . HOH BA 10 . ? 73.591 -28.389 -31.004 1.00 27.77 ? 1192 HOH A O 1 HETATM 9075 O O . HOH BA 10 . ? 91.934 -21.987 -34.111 1.00 29.57 ? 1193 HOH A O 1 HETATM 9076 O O . HOH BA 10 . ? 41.619 5.691 -35.534 1.00 22.37 ? 1194 HOH A O 1 HETATM 9077 O O . HOH BA 10 . ? 35.882 -10.390 -39.348 1.00 24.77 ? 1195 HOH A O 1 HETATM 9078 O O . HOH BA 10 . ? 75.012 1.408 -49.505 1.00 23.45 ? 1196 HOH A O 1 HETATM 9079 O O . HOH BA 10 . ? 82.610 5.508 -42.706 1.00 25.06 ? 1197 HOH A O 1 HETATM 9080 O O . HOH BA 10 . ? 49.425 -0.860 -40.724 1.00 23.65 ? 1198 HOH A O 1 HETATM 9081 O O . HOH BA 10 . ? 47.220 12.894 -17.778 1.00 31.64 ? 1199 HOH A O 1 HETATM 9082 O O . HOH BA 10 . ? 88.832 -29.293 -44.313 1.00 29.71 ? 1200 HOH A O 1 HETATM 9083 O O . HOH BA 10 . ? 54.762 18.739 -33.721 1.00 22.86 ? 1201 HOH A O 1 HETATM 9084 O O . HOH BA 10 . ? 60.297 -20.134 -24.374 1.00 25.90 ? 1202 HOH A O 1 HETATM 9085 O O . HOH BA 10 . ? 96.995 -5.596 -46.533 1.00 27.66 ? 1203 HOH A O 1 HETATM 9086 O O . HOH BA 10 . ? 33.634 1.727 -10.617 1.00 25.08 ? 1204 HOH A O 1 HETATM 9087 O O . HOH BA 10 . ? 72.749 -25.795 -52.932 1.00 24.19 ? 1205 HOH A O 1 HETATM 9088 O O . HOH BA 10 . ? 79.874 14.993 -31.930 1.00 20.72 ? 1206 HOH A O 1 HETATM 9089 O O . HOH BA 10 . ? 79.982 13.773 -28.304 1.00 24.55 ? 1207 HOH A O 1 HETATM 9090 O O . HOH BA 10 . ? 71.100 -14.894 -9.824 1.00 29.50 ? 1208 HOH A O 1 HETATM 9091 O O . HOH BA 10 . ? 88.158 8.920 -22.989 1.00 27.06 ? 1209 HOH A O 1 HETATM 9092 O O . HOH BA 10 . ? 59.901 -4.426 -49.361 1.00 32.86 ? 1210 HOH A O 1 HETATM 9093 O O . HOH BA 10 . ? 56.876 -0.716 -48.250 1.00 28.53 ? 1211 HOH A O 1 HETATM 9094 O O . HOH BA 10 . ? 36.418 1.978 -32.457 1.00 26.33 ? 1212 HOH A O 1 HETATM 9095 O O . HOH BA 10 . ? 75.722 -20.086 -9.541 1.00 28.30 ? 1213 HOH A O 1 HETATM 9096 O O . HOH BA 10 . ? 75.080 -25.755 -15.318 1.00 21.43 ? 1214 HOH A O 1 HETATM 9097 O O . HOH BA 10 . ? 43.780 -19.485 -37.645 1.00 26.59 ? 1215 HOH A O 1 HETATM 9098 O O . HOH BA 10 . ? 68.299 -22.401 -15.828 1.00 26.50 ? 1216 HOH A O 1 HETATM 9099 O O . HOH BA 10 . ? 37.563 -17.284 -28.721 1.00 24.56 ? 1217 HOH A O 1 HETATM 9100 O O . HOH BA 10 . ? 91.307 6.581 -21.519 1.00 26.29 ? 1218 HOH A O 1 HETATM 9101 O O . HOH BA 10 . ? 54.675 -17.545 -45.883 1.00 34.75 ? 1219 HOH A O 1 HETATM 9102 O O . HOH BA 10 . ? 62.198 6.646 -7.938 1.00 29.85 ? 1220 HOH A O 1 HETATM 9103 O O . HOH BA 10 . ? 42.661 -17.518 -31.990 1.00 32.65 ? 1221 HOH A O 1 HETATM 9104 O O . HOH BA 10 . ? 82.440 -23.636 -18.628 1.00 22.95 ? 1222 HOH A O 1 HETATM 9105 O O . HOH BA 10 . ? 77.377 -19.279 -62.264 1.00 31.06 ? 1223 HOH A O 1 HETATM 9106 O O . HOH BA 10 . ? 69.457 16.042 -24.884 1.00 40.92 ? 1224 HOH A O 1 HETATM 9107 O O . HOH BA 10 . ? 58.101 11.319 -29.769 1.00 34.76 ? 1225 HOH A O 1 HETATM 9108 O O . HOH BA 10 . ? 84.883 -8.810 -51.797 1.00 31.05 ? 1226 HOH A O 1 HETATM 9109 O O . HOH BA 10 . ? 35.486 -10.824 -23.466 1.00 30.65 ? 1227 HOH A O 1 HETATM 9110 O O . HOH BA 10 . ? 82.026 7.324 -16.369 1.00 28.25 ? 1228 HOH A O 1 HETATM 9111 O O . HOH BA 10 . ? 102.646 -12.687 -39.743 1.00 26.95 ? 1229 HOH A O 1 HETATM 9112 O O . HOH BA 10 . ? 80.052 10.197 -13.505 1.00 27.32 ? 1230 HOH A O 1 HETATM 9113 O O . HOH BA 10 . ? 85.051 -23.534 -26.960 1.00 34.65 ? 1231 HOH A O 1 HETATM 9114 O O . HOH BA 10 . ? 84.935 3.182 -48.160 1.00 40.60 ? 1232 HOH A O 1 HETATM 9115 O O . HOH BA 10 . ? 83.104 -21.819 -15.560 1.00 26.83 ? 1233 HOH A O 1 HETATM 9116 O O . HOH BA 10 . ? 98.969 -20.535 -26.946 1.00 39.93 ? 1234 HOH A O 1 HETATM 9117 O O . HOH BA 10 . ? 90.867 -13.909 -17.917 1.00 26.55 ? 1235 HOH A O 1 HETATM 9118 O O . HOH BA 10 . ? 70.722 14.087 -26.210 1.00 22.16 ? 1236 HOH A O 1 HETATM 9119 O O . HOH BA 10 . ? 72.401 4.335 -47.336 1.00 27.12 ? 1237 HOH A O 1 HETATM 9120 O O . HOH BA 10 . ? 85.712 -24.427 -23.190 1.00 26.03 ? 1238 HOH A O 1 HETATM 9121 O O . HOH BA 10 . ? 75.176 -27.546 -36.851 1.00 29.01 ? 1239 HOH A O 1 HETATM 9122 O O . HOH BA 10 . ? 89.903 1.178 -53.381 1.00 25.46 ? 1240 HOH A O 1 HETATM 9123 O O . HOH BA 10 . ? 72.900 -13.111 -9.763 1.00 27.25 ? 1241 HOH A O 1 HETATM 9124 O O . HOH BA 10 . ? 46.209 -13.165 -17.896 1.00 30.16 ? 1242 HOH A O 1 HETATM 9125 O O . HOH BA 10 . ? 81.152 10.805 -20.822 1.00 27.10 ? 1243 HOH A O 1 HETATM 9126 O O . HOH BA 10 . ? 79.203 -10.067 -8.924 1.00 31.90 ? 1244 HOH A O 1 HETATM 9127 O O . HOH BA 10 . ? 81.471 -12.370 -60.864 1.00 27.38 ? 1245 HOH A O 1 HETATM 9128 O O . HOH BA 10 . ? 83.176 -14.501 -61.882 1.00 30.24 ? 1246 HOH A O 1 HETATM 9129 O O . HOH BA 10 . ? 35.396 -15.446 -25.799 1.00 29.22 ? 1247 HOH A O 1 HETATM 9130 O O . HOH BA 10 . ? 73.865 -26.049 -49.978 1.00 30.90 ? 1248 HOH A O 1 HETATM 9131 O O . HOH BA 10 . ? 34.639 -6.308 -38.183 1.00 30.13 ? 1249 HOH A O 1 HETATM 9132 O O . HOH BA 10 . ? 73.648 -17.109 -9.296 1.00 23.01 ? 1250 HOH A O 1 HETATM 9133 O O . HOH BA 10 . ? 35.175 -0.276 -19.840 1.00 24.52 ? 1251 HOH A O 1 HETATM 9134 O O . HOH BA 10 . ? 60.263 -16.584 -47.356 1.00 35.39 ? 1252 HOH A O 1 HETATM 9135 O O . HOH BA 10 . ? 73.747 -4.722 -7.429 1.00 28.44 ? 1253 HOH A O 1 HETATM 9136 O O . HOH BA 10 . ? 77.642 -29.440 -30.957 1.00 36.49 ? 1254 HOH A O 1 HETATM 9137 O O . HOH BA 10 . ? 70.846 -7.862 -8.948 1.00 29.37 ? 1255 HOH A O 1 HETATM 9138 O O . HOH BA 10 . ? 75.233 -27.798 -42.777 1.00 24.15 ? 1256 HOH A O 1 HETATM 9139 O O . HOH BA 10 . ? 62.593 -15.491 -47.647 1.00 27.12 ? 1257 HOH A O 1 HETATM 9140 O O . HOH BA 10 . ? 63.086 4.972 -24.785 1.00 27.67 ? 1258 HOH A O 1 HETATM 9141 O O . HOH BA 10 . ? 43.999 10.282 -12.828 1.00 44.81 ? 1259 HOH A O 1 HETATM 9142 O O . HOH BA 10 . ? 94.950 -5.101 -48.297 1.00 30.34 ? 1260 HOH A O 1 HETATM 9143 O O . HOH BA 10 . ? 83.779 -0.649 -16.403 1.00 24.92 ? 1261 HOH A O 1 HETATM 9144 O O . HOH BA 10 . ? 62.116 2.969 -23.369 1.00 13.17 ? 1262 HOH A O 1 HETATM 9145 O O . HOH BA 10 . ? 69.900 -3.081 -43.380 1.00 15.05 ? 1263 HOH A O 1 HETATM 9146 O O . HOH BA 10 . ? 49.651 4.951 -10.954 1.00 22.57 ? 1264 HOH A O 1 HETATM 9147 O O . HOH BA 10 . ? 52.928 -14.531 -5.865 1.00 24.12 ? 1265 HOH A O 1 HETATM 9148 O O . HOH BA 10 . ? 87.694 -15.241 -15.574 1.00 24.34 ? 1266 HOH A O 1 HETATM 9149 O O . HOH BA 10 . ? 90.308 -24.762 -18.770 1.00 30.46 ? 1267 HOH A O 1 HETATM 9150 O O . HOH BA 10 . ? 87.061 -18.990 -16.334 1.00 28.05 ? 1268 HOH A O 1 HETATM 9151 O O . HOH BA 10 . ? 52.684 17.175 -34.356 1.00 24.56 ? 1269 HOH A O 1 HETATM 9152 O O . HOH BA 10 . ? 66.347 -24.043 -45.244 1.00 29.78 ? 1270 HOH A O 1 HETATM 9153 O O . HOH BA 10 . ? 59.093 15.488 -30.448 1.00 22.72 ? 1271 HOH A O 1 HETATM 9154 O O . HOH BA 10 . ? 52.557 16.386 -20.338 1.00 25.33 ? 1272 HOH A O 1 HETATM 9155 O O . HOH BA 10 . ? 89.599 -19.416 -50.118 1.00 31.75 ? 1273 HOH A O 1 HETATM 9156 O O . HOH BA 10 . ? 62.462 13.728 -26.484 1.00 28.86 ? 1274 HOH A O 1 HETATM 9157 O O . HOH BA 10 . ? 75.038 -8.750 -9.756 1.00 24.68 ? 1275 HOH A O 1 HETATM 9158 O O . HOH BA 10 . ? 86.675 -8.814 -16.470 1.00 28.27 ? 1276 HOH A O 1 HETATM 9159 O O . HOH BA 10 . ? 30.033 2.258 -31.112 1.00 24.22 ? 1277 HOH A O 1 HETATM 9160 O O . HOH BA 10 . ? 30.837 -3.979 -32.697 1.00 34.40 ? 1278 HOH A O 1 HETATM 9161 O O . HOH BA 10 . ? 66.632 -25.052 -34.652 1.00 30.85 ? 1279 HOH A O 1 HETATM 9162 O O . HOH BA 10 . ? 78.399 6.201 -10.107 1.00 30.12 ? 1280 HOH A O 1 HETATM 9163 O O . HOH BA 10 . ? 83.622 8.021 -42.160 1.00 27.03 ? 1281 HOH A O 1 HETATM 9164 O O . HOH BA 10 . ? 80.408 -12.639 -57.973 1.00 29.89 ? 1282 HOH A O 1 HETATM 9165 O O . HOH BA 10 . ? 80.710 -7.232 -11.596 1.00 28.38 ? 1283 HOH A O 1 HETATM 9166 O O . HOH BA 10 . ? 77.982 -27.716 -44.365 1.00 25.80 ? 1284 HOH A O 1 HETATM 9167 O O . HOH BA 10 . ? 58.574 -18.869 -25.964 1.00 32.20 ? 1285 HOH A O 1 HETATM 9168 O O . HOH BA 10 . ? 72.486 -10.507 -55.801 1.00 28.12 ? 1286 HOH A O 1 HETATM 9169 O O . HOH BA 10 . ? 56.682 3.284 -45.972 1.00 31.79 ? 1287 HOH A O 1 HETATM 9170 O O . HOH BA 10 . ? 101.711 -12.624 -22.609 1.00 30.81 ? 1288 HOH A O 1 HETATM 9171 O O . HOH BA 10 . ? 38.147 4.305 -32.336 1.00 31.42 ? 1289 HOH A O 1 HETATM 9172 O O . HOH BA 10 . ? 67.736 -10.083 -52.976 1.00 29.95 ? 1290 HOH A O 1 HETATM 9173 O O . HOH BA 10 . ? 58.163 -2.314 -7.440 1.00 33.07 ? 1291 HOH A O 1 HETATM 9174 O O . HOH BA 10 . ? 74.980 3.634 -47.829 1.00 30.37 ? 1292 HOH A O 1 HETATM 9175 O O . HOH BA 10 . ? 80.789 -3.721 -55.614 1.00 35.30 ? 1293 HOH A O 1 HETATM 9176 O O . HOH BA 10 . ? 60.146 13.175 -29.739 1.00 27.42 ? 1294 HOH A O 1 HETATM 9177 O O . HOH BA 10 . ? 93.044 -6.508 -49.647 1.00 30.96 ? 1295 HOH A O 1 HETATM 9178 O O . HOH BA 10 . ? 101.374 -4.910 -38.572 1.00 29.84 ? 1296 HOH A O 1 HETATM 9179 O O . HOH BA 10 . ? 67.659 3.944 -46.335 1.00 32.58 ? 1297 HOH A O 1 HETATM 9180 O O . HOH BA 10 . ? 40.916 15.271 -26.955 1.00 26.23 ? 1298 HOH A O 1 HETATM 9181 O O . HOH BA 10 . ? 62.404 -24.435 -24.632 1.00 27.28 ? 1299 HOH A O 1 HETATM 9182 O O . HOH BA 10 . ? 101.176 -8.521 -39.794 1.00 30.33 ? 1300 HOH A O 1 HETATM 9183 O O . HOH BA 10 . ? 48.605 15.348 -36.365 1.00 26.95 ? 1301 HOH A O 1 HETATM 9184 O O . HOH BA 10 . ? 96.090 6.019 -26.713 1.00 29.95 ? 1302 HOH A O 1 HETATM 9185 O O . HOH BA 10 . ? 37.656 14.653 -22.652 1.00 30.86 ? 1303 HOH A O 1 HETATM 9186 O O . HOH BA 10 . ? 49.905 -16.296 -19.452 1.00 25.63 ? 1304 HOH A O 1 HETATM 9187 O O . HOH BA 10 . ? 39.882 -15.032 -24.015 1.00 29.15 ? 1305 HOH A O 1 HETATM 9188 O O . HOH BA 10 . ? 92.968 -16.632 -49.840 1.00 33.30 ? 1306 HOH A O 1 HETATM 9189 O O . HOH BA 10 . ? 77.399 -1.354 -55.268 1.00 31.75 ? 1307 HOH A O 1 HETATM 9190 O O . HOH BA 10 . ? 44.790 10.644 -35.794 1.00 31.93 ? 1308 HOH A O 1 HETATM 9191 O O . HOH BA 10 . ? 65.398 5.935 -8.152 1.00 38.93 ? 1309 HOH A O 1 HETATM 9192 O O . HOH BA 10 . ? 48.388 -24.217 -40.235 1.00 29.21 ? 1310 HOH A O 1 HETATM 9193 O O . HOH BA 10 . ? 69.182 -21.886 -50.614 1.00 31.71 ? 1311 HOH A O 1 HETATM 9194 O O . HOH BA 10 . ? 50.470 17.493 -16.615 1.00 28.61 ? 1312 HOH A O 1 HETATM 9195 O O . HOH BA 10 . ? 83.365 5.181 -47.191 1.00 31.30 ? 1313 HOH A O 1 HETATM 9196 O O . HOH BA 10 . ? 50.794 7.350 -11.588 1.00 27.12 ? 1314 HOH A O 1 HETATM 9197 O O . HOH BA 10 . ? 53.262 -24.642 -30.958 1.00 29.10 ? 1315 HOH A O 1 HETATM 9198 O O . HOH BA 10 . ? 77.012 1.694 -51.310 1.00 34.01 ? 1316 HOH A O 1 HETATM 9199 O O . HOH BA 10 . ? 47.812 -23.135 -32.299 1.00 39.44 ? 1317 HOH A O 1 HETATM 9200 O O . HOH BA 10 . ? 51.377 -17.277 -9.307 1.00 28.24 ? 1318 HOH A O 1 HETATM 9201 O O . HOH BA 10 . ? 82.437 -29.324 -37.669 1.00 26.37 ? 1319 HOH A O 1 HETATM 9202 O O . HOH BA 10 . ? 57.841 -17.611 -12.941 1.00 36.73 ? 1320 HOH A O 1 HETATM 9203 O O . HOH BA 10 . ? 46.945 -15.822 -11.870 1.00 30.88 ? 1321 HOH A O 1 HETATM 9204 O O . HOH BA 10 . ? 59.310 11.899 -26.055 1.00 30.53 ? 1322 HOH A O 1 HETATM 9205 O O . HOH BA 10 . ? 41.173 -19.031 -36.916 1.00 39.78 ? 1323 HOH A O 1 HETATM 9206 O O . HOH BA 10 . ? 82.620 -24.096 -25.638 1.00 34.59 ? 1324 HOH A O 1 HETATM 9207 O O . HOH BA 10 . ? 64.483 -24.113 -35.977 1.00 40.42 ? 1325 HOH A O 1 HETATM 9208 O O . HOH BA 10 . ? 58.584 0.130 -26.853 1.00 43.02 ? 1326 HOH A O 1 HETATM 9209 O O . HOH BA 10 . ? 79.373 -25.874 -20.326 1.00 25.47 ? 1327 HOH A O 1 HETATM 9210 O O . HOH BA 10 . ? 75.304 -28.961 -33.152 1.00 40.52 ? 1328 HOH A O 1 HETATM 9211 O O . HOH BA 10 . ? 84.654 -24.918 -20.726 1.00 38.62 ? 1329 HOH A O 1 HETATM 9212 O O . HOH BA 10 . ? 39.819 -0.226 -38.725 1.00 26.76 ? 1330 HOH A O 1 HETATM 9213 O O . HOH BA 10 . ? 34.822 -0.137 -12.141 1.00 42.39 ? 1331 HOH A O 1 HETATM 9214 O O . HOH BA 10 . ? 77.312 -8.324 -8.450 1.00 35.97 ? 1332 HOH A O 1 HETATM 9215 O O . HOH BA 10 . ? 89.934 -3.210 -17.281 1.00 27.67 ? 1333 HOH A O 1 HETATM 9216 O O . HOH BA 10 . ? 82.631 11.819 -17.675 1.00 37.48 ? 1334 HOH A O 1 HETATM 9217 O O . HOH BA 10 . ? 80.681 4.526 -15.541 1.00 32.57 ? 1335 HOH A O 1 HETATM 9218 O O . HOH BA 10 . ? 53.979 -22.417 -29.396 1.00 30.66 ? 1336 HOH A O 1 HETATM 9219 O O . HOH BA 10 . ? 59.649 8.084 -42.472 1.00 27.74 ? 1337 HOH A O 1 HETATM 9220 O O . HOH BA 10 . ? 96.339 -16.309 -40.369 1.00 28.14 ? 1338 HOH A O 1 HETATM 9221 O O . HOH BA 10 . ? 74.953 13.617 -44.230 1.00 36.66 ? 1339 HOH A O 1 HETATM 9222 O O . HOH BA 10 . ? 62.351 17.090 -33.004 1.00 40.97 ? 1340 HOH A O 1 HETATM 9223 O O . HOH BA 10 . ? 57.603 -6.332 -51.414 1.00 33.52 ? 1341 HOH A O 1 HETATM 9224 O O . HOH BA 10 . ? 40.010 -4.490 -43.039 1.00 31.68 ? 1342 HOH A O 1 HETATM 9225 O O . HOH BA 10 . ? 97.361 3.654 -47.619 1.00 30.17 ? 1343 HOH A O 1 HETATM 9226 O O . HOH BA 10 . ? 80.412 -10.157 -57.524 1.00 31.73 ? 1344 HOH A O 1 HETATM 9227 O O . HOH BA 10 . ? 100.877 -22.617 -31.421 1.00 30.04 ? 1345 HOH A O 1 HETATM 9228 O O . HOH BA 10 . ? 34.302 4.014 -31.439 1.00 38.54 ? 1346 HOH A O 1 HETATM 9229 O O . HOH BA 10 . ? 82.712 -1.984 -14.283 1.00 33.32 ? 1347 HOH A O 1 HETATM 9230 O O . HOH BA 10 . ? 67.319 -25.208 -47.492 1.00 34.23 ? 1348 HOH A O 1 HETATM 9231 O O . HOH BA 10 . ? 56.585 -25.440 -23.030 1.00 44.25 ? 1349 HOH A O 1 HETATM 9232 O O . HOH BA 10 . ? 76.088 15.812 -43.427 1.00 33.39 ? 1350 HOH A O 1 HETATM 9233 O O . HOH BA 10 . ? 100.435 -20.503 -29.614 1.00 38.40 ? 1351 HOH A O 1 HETATM 9234 O O . HOH BA 10 . ? 63.589 -24.904 -29.282 1.00 37.29 ? 1352 HOH A O 1 HETATM 9235 O O . HOH BA 10 . ? 48.880 -18.997 -16.481 1.00 37.66 ? 1353 HOH A O 1 HETATM 9236 O O . HOH BA 10 . ? 50.653 17.927 -14.031 1.00 31.85 ? 1366 HOH A O 1 HETATM 9237 O O . HOH BA 10 . ? 62.969 16.068 -30.704 1.00 34.90 ? 1504 HOH A O 1 HETATM 9238 O O . HOH BA 10 . ? 59.492 16.640 -16.121 1.00 44.31 ? 1584 HOH A O 1 HETATM 9239 O O . HOH CA 10 . ? 37.964 7.523 -13.327 1.00 23.59 ? 535 HOH B O 1 HETATM 9240 O O . HOH CA 10 . ? 39.316 11.590 -14.579 1.00 34.29 ? 590 HOH B O 1 HETATM 9241 O O . HOH CA 10 . ? 36.172 7.272 -19.220 1.00 30.71 ? 625 HOH B O 1 HETATM 9242 O O . HOH CA 10 . ? 36.551 14.083 -16.180 1.00 37.31 ? 826 HOH B O 1 HETATM 9243 O O . HOH CA 10 . ? 36.076 36.883 -0.726 1.00 7.57 ? 829 HOH B O 1 HETATM 9244 O O . HOH CA 10 . ? 45.471 26.078 -20.975 1.00 7.65 ? 830 HOH B O 1 HETATM 9245 O O . HOH CA 10 . ? 53.344 38.712 -24.360 1.00 10.83 ? 831 HOH B O 1 HETATM 9246 O O . HOH CA 10 . ? 36.011 35.276 6.519 1.00 11.48 ? 832 HOH B O 1 HETATM 9247 O O . HOH CA 10 . ? 35.827 41.109 -22.020 1.00 8.53 ? 833 HOH B O 1 HETATM 9248 O O . HOH CA 10 . ? 44.637 54.350 -8.646 1.00 11.29 ? 834 HOH B O 1 HETATM 9249 O O . HOH CA 10 . ? 34.537 32.520 -19.667 1.00 8.04 ? 835 HOH B O 1 HETATM 9250 O O . HOH CA 10 . ? 30.723 46.549 -0.831 1.00 9.28 ? 836 HOH B O 1 HETATM 9251 O O . HOH CA 10 . ? 56.619 32.811 2.568 1.00 13.23 ? 837 HOH B O 1 HETATM 9252 O O . HOH CA 10 . ? 48.428 39.353 -31.073 1.00 12.46 ? 838 HOH B O 1 HETATM 9253 O O . HOH CA 10 . ? 29.655 32.781 -18.027 1.00 7.97 ? 839 HOH B O 1 HETATM 9254 O O . HOH CA 10 . ? 39.684 48.087 -1.790 1.00 10.81 ? 840 HOH B O 1 HETATM 9255 O O . HOH CA 10 . ? 48.733 42.725 -17.874 1.00 7.56 ? 841 HOH B O 1 HETATM 9256 O O . HOH CA 10 . ? 29.320 29.109 -12.133 1.00 11.56 ? 842 HOH B O 1 HETATM 9257 O O . HOH CA 10 . ? 44.774 31.084 -12.541 1.00 11.60 ? 843 HOH B O 1 HETATM 9258 O O . HOH CA 10 . ? 32.575 36.935 3.407 1.00 10.76 ? 844 HOH B O 1 HETATM 9259 O O . HOH CA 10 . ? 49.264 40.856 -19.717 1.00 8.61 ? 845 HOH B O 1 HETATM 9260 O O . HOH CA 10 . ? 46.841 39.575 -18.790 1.00 8.77 ? 846 HOH B O 1 HETATM 9261 O O . HOH CA 10 . ? 46.388 37.761 -15.421 1.00 8.24 ? 847 HOH B O 1 HETATM 9262 O O . HOH CA 10 . ? 52.970 38.929 -13.015 1.00 8.63 ? 848 HOH B O 1 HETATM 9263 O O . HOH CA 10 . ? 33.225 45.173 -18.992 1.00 10.17 ? 849 HOH B O 1 HETATM 9264 O O . HOH CA 10 . ? 40.828 26.334 -10.654 1.00 11.61 ? 850 HOH B O 1 HETATM 9265 O O . HOH CA 10 . ? 42.352 39.522 -3.471 1.00 7.65 ? 851 HOH B O 1 HETATM 9266 O O . HOH CA 10 . ? 42.657 35.879 -3.759 1.00 9.14 ? 852 HOH B O 1 HETATM 9267 O O . HOH CA 10 . ? 26.585 36.033 12.143 1.00 9.24 ? 853 HOH B O 1 HETATM 9268 O O . HOH CA 10 . ? 23.025 48.234 -17.371 1.00 11.80 ? 854 HOH B O 1 HETATM 9269 O O . HOH CA 10 . ? 31.468 42.385 8.761 1.00 10.71 ? 855 HOH B O 1 HETATM 9270 O O . HOH CA 10 . ? 51.129 39.156 -31.337 1.00 8.52 ? 856 HOH B O 1 HETATM 9271 O O . HOH CA 10 . ? 32.191 33.698 -18.668 1.00 7.80 ? 857 HOH B O 1 HETATM 9272 O O . HOH CA 10 . ? 46.662 47.962 -5.294 1.00 10.63 ? 858 HOH B O 1 HETATM 9273 O O . HOH CA 10 . ? 33.768 50.503 -21.748 1.00 10.44 ? 859 HOH B O 1 HETATM 9274 O O . HOH CA 10 . ? 25.600 37.494 -22.628 1.00 15.30 ? 860 HOH B O 1 HETATM 9275 O O . HOH CA 10 . ? 51.580 41.218 -23.802 1.00 10.41 ? 861 HOH B O 1 HETATM 9276 O O . HOH CA 10 . ? 35.484 29.941 -8.601 1.00 15.12 ? 862 HOH B O 1 HETATM 9277 O O . HOH CA 10 . ? 44.131 41.305 -15.026 1.00 12.71 ? 863 HOH B O 1 HETATM 9278 O O . HOH CA 10 . ? 36.077 38.450 -14.426 1.00 10.71 ? 864 HOH B O 1 HETATM 9279 O O . HOH CA 10 . ? 24.911 37.467 -10.620 1.00 14.76 ? 865 HOH B O 1 HETATM 9280 O O . HOH CA 10 . ? 46.382 32.097 9.047 1.00 31.36 ? 866 HOH B O 1 HETATM 9281 O O . HOH CA 10 . ? 42.681 31.599 -10.970 1.00 12.07 ? 867 HOH B O 1 HETATM 9282 O O . HOH CA 10 . ? 42.856 52.391 -12.077 1.00 9.98 ? 868 HOH B O 1 HETATM 9283 O O . HOH CA 10 . ? 24.393 44.012 -15.478 1.00 13.27 ? 869 HOH B O 1 HETATM 9284 O O . HOH CA 10 . ? 49.884 42.642 -26.584 1.00 12.60 ? 870 HOH B O 1 HETATM 9285 O O . HOH CA 10 . ? 32.129 27.130 -22.411 1.00 13.36 ? 871 HOH B O 1 HETATM 9286 O O . HOH CA 10 . ? 40.540 35.200 -11.125 1.00 11.33 ? 872 HOH B O 1 HETATM 9287 O O . HOH CA 10 . ? 32.630 50.425 6.936 1.00 11.99 ? 873 HOH B O 1 HETATM 9288 O O . HOH CA 10 . ? 52.875 43.338 -25.026 1.00 9.38 ? 874 HOH B O 1 HETATM 9289 O O . HOH CA 10 . ? 49.298 21.559 -24.082 1.00 11.98 ? 875 HOH B O 1 HETATM 9290 O O . HOH CA 10 . ? 24.821 46.685 -18.958 1.00 12.51 ? 876 HOH B O 1 HETATM 9291 O O . HOH CA 10 . ? 39.560 40.226 -28.700 1.00 13.44 ? 877 HOH B O 1 HETATM 9292 O O . HOH CA 10 . ? 26.530 43.745 -22.271 1.00 12.80 ? 878 HOH B O 1 HETATM 9293 O O . HOH CA 10 . ? 14.808 39.425 -5.442 1.00 12.62 ? 879 HOH B O 1 HETATM 9294 O O . HOH CA 10 . ? 44.671 30.399 4.001 1.00 10.98 ? 880 HOH B O 1 HETATM 9295 O O . HOH CA 10 . ? 39.625 26.611 -25.087 1.00 11.84 ? 881 HOH B O 1 HETATM 9296 O O . HOH CA 10 . ? 52.919 57.502 -1.599 1.00 18.16 ? 882 HOH B O 1 HETATM 9297 O O . HOH CA 10 . ? 25.930 37.416 -1.940 1.00 13.11 ? 883 HOH B O 1 HETATM 9298 O O . HOH CA 10 . ? 38.669 24.802 -18.048 1.00 15.21 ? 884 HOH B O 1 HETATM 9299 O O . HOH CA 10 . ? 42.332 39.336 -14.189 1.00 11.29 ? 885 HOH B O 1 HETATM 9300 O O . HOH CA 10 . ? 37.420 49.868 -4.511 1.00 15.19 ? 886 HOH B O 1 HETATM 9301 O O . HOH CA 10 . ? 66.021 26.535 -10.784 1.00 15.83 ? 887 HOH B O 1 HETATM 9302 O O . HOH CA 10 . ? 60.560 23.533 -17.217 1.00 12.50 ? 888 HOH B O 1 HETATM 9303 O O . HOH CA 10 . ? 32.317 52.637 -18.876 1.00 13.51 ? 889 HOH B O 1 HETATM 9304 O O . HOH CA 10 . ? 52.945 52.355 -18.054 1.00 12.20 ? 890 HOH B O 1 HETATM 9305 O O . HOH CA 10 . ? 14.238 49.212 -0.129 1.00 14.68 ? 891 HOH B O 1 HETATM 9306 O O . HOH CA 10 . ? 46.287 47.409 8.775 1.00 13.14 ? 892 HOH B O 1 HETATM 9307 O O . HOH CA 10 . ? 43.770 30.540 1.462 1.00 18.24 ? 893 HOH B O 1 HETATM 9308 O O . HOH CA 10 . ? 19.007 34.265 -4.906 1.00 13.20 ? 894 HOH B O 1 HETATM 9309 O O . HOH CA 10 . ? 34.926 50.175 5.186 1.00 12.46 ? 895 HOH B O 1 HETATM 9310 O O . HOH CA 10 . ? 21.062 44.919 8.769 1.00 12.65 ? 896 HOH B O 1 HETATM 9311 O O . HOH CA 10 . ? 49.589 56.838 2.992 1.00 14.39 ? 897 HOH B O 1 HETATM 9312 O O . HOH CA 10 . ? 17.653 56.258 -6.263 1.00 15.38 ? 898 HOH B O 1 HETATM 9313 O O . HOH CA 10 . ? 18.633 30.422 -10.680 1.00 15.15 ? 899 HOH B O 1 HETATM 9314 O O . HOH CA 10 . ? 42.826 51.031 4.318 1.00 14.59 ? 900 HOH B O 1 HETATM 9315 O O . HOH CA 10 . ? 74.555 33.744 -8.619 1.00 14.65 ? 901 HOH B O 1 HETATM 9316 O O . HOH CA 10 . ? 45.029 54.004 -21.089 1.00 13.78 ? 902 HOH B O 1 HETATM 9317 O O . HOH CA 10 . ? 41.688 37.446 8.588 1.00 12.31 ? 903 HOH B O 1 HETATM 9318 O O . HOH CA 10 . ? 18.416 32.732 -21.598 1.00 13.24 ? 904 HOH B O 1 HETATM 9319 O O . HOH CA 10 . ? 57.321 41.201 -31.141 1.00 16.40 ? 905 HOH B O 1 HETATM 9320 O O . HOH CA 10 . ? 41.796 53.464 -20.466 1.00 12.76 ? 906 HOH B O 1 HETATM 9321 O O . HOH CA 10 . ? 46.846 46.202 -29.831 1.00 17.00 ? 907 HOH B O 1 HETATM 9322 O O . HOH CA 10 . ? 18.582 60.658 -8.116 1.00 15.33 ? 908 HOH B O 1 HETATM 9323 O O . HOH CA 10 . ? 20.334 32.743 7.872 1.00 16.23 ? 909 HOH B O 1 HETATM 9324 O O . HOH CA 10 . ? 26.564 38.048 -12.546 1.00 13.10 ? 910 HOH B O 1 HETATM 9325 O O . HOH CA 10 . ? 32.482 29.669 -5.079 1.00 14.88 ? 911 HOH B O 1 HETATM 9326 O O . HOH CA 10 . ? 21.627 49.551 -13.474 1.00 14.56 ? 912 HOH B O 1 HETATM 9327 O O . HOH CA 10 . ? 13.930 43.241 6.308 1.00 15.04 ? 913 HOH B O 1 HETATM 9328 O O . HOH CA 10 . ? 40.162 32.138 2.743 1.00 13.60 ? 914 HOH B O 1 HETATM 9329 O O . HOH CA 10 . ? 24.097 29.584 -23.622 1.00 14.87 ? 915 HOH B O 1 HETATM 9330 O O . HOH CA 10 . ? 19.963 52.708 5.698 1.00 15.43 ? 916 HOH B O 1 HETATM 9331 O O . HOH CA 10 . ? 56.259 34.993 6.271 1.00 15.68 ? 917 HOH B O 1 HETATM 9332 O O . HOH CA 10 . ? 54.620 18.287 -23.477 1.00 16.15 ? 918 HOH B O 1 HETATM 9333 O O . HOH CA 10 . ? 58.243 31.140 4.181 1.00 16.33 ? 919 HOH B O 1 HETATM 9334 O O . HOH CA 10 . ? 16.676 37.803 4.692 1.00 14.03 ? 920 HOH B O 1 HETATM 9335 O O . HOH CA 10 . ? 35.560 26.791 -5.648 1.00 28.25 ? 921 HOH B O 1 HETATM 9336 O O . HOH CA 10 . ? 19.511 54.923 -17.710 1.00 22.34 ? 922 HOH B O 1 HETATM 9337 O O . HOH CA 10 . ? 51.283 47.530 -25.370 1.00 13.68 ? 923 HOH B O 1 HETATM 9338 O O . HOH CA 10 . ? 51.583 58.170 4.133 1.00 21.40 ? 924 HOH B O 1 HETATM 9339 O O . HOH CA 10 . ? 54.259 23.546 -6.772 1.00 15.25 ? 925 HOH B O 1 HETATM 9340 O O . HOH CA 10 . ? 71.453 24.277 -6.835 1.00 19.34 ? 926 HOH B O 1 HETATM 9341 O O . HOH CA 10 . ? 63.251 50.959 -23.211 1.00 19.05 ? 927 HOH B O 1 HETATM 9342 O O . HOH CA 10 . ? 30.840 30.722 6.718 1.00 20.31 ? 928 HOH B O 1 HETATM 9343 O O . HOH CA 10 . ? 59.208 20.144 -18.059 1.00 16.48 ? 929 HOH B O 1 HETATM 9344 O O . HOH CA 10 . ? 47.875 20.670 -34.163 1.00 16.05 ? 930 HOH B O 1 HETATM 9345 O O . HOH CA 10 . ? 48.963 37.552 -0.873 1.00 13.02 ? 931 HOH B O 1 HETATM 9346 O O . HOH CA 10 . ? 55.965 50.992 -22.443 1.00 16.46 ? 932 HOH B O 1 HETATM 9347 O O . HOH CA 10 . ? 52.553 19.889 -6.837 1.00 17.35 ? 933 HOH B O 1 HETATM 9348 O O . HOH CA 10 . ? 40.787 44.298 -28.449 1.00 19.84 ? 934 HOH B O 1 HETATM 9349 O O . HOH CA 10 . ? 48.388 59.456 -13.885 1.00 16.22 ? 935 HOH B O 1 HETATM 9350 O O . HOH CA 10 . ? 22.134 46.923 -15.256 1.00 17.27 ? 936 HOH B O 1 HETATM 9351 O O . HOH CA 10 . ? 29.508 27.591 -7.878 1.00 20.84 ? 937 HOH B O 1 HETATM 9352 O O . HOH CA 10 . ? 40.376 33.763 -29.822 1.00 22.05 ? 938 HOH B O 1 HETATM 9353 O O . HOH CA 10 . ? 26.567 56.528 2.863 1.00 18.76 ? 939 HOH B O 1 HETATM 9354 O O . HOH CA 10 . ? 71.208 29.389 -11.956 1.00 13.93 ? 940 HOH B O 1 HETATM 9355 O O . HOH CA 10 . ? 70.492 40.886 -11.198 1.00 15.93 ? 941 HOH B O 1 HETATM 9356 O O . HOH CA 10 . ? 32.098 46.873 -26.753 1.00 18.85 ? 942 HOH B O 1 HETATM 9357 O O . HOH CA 10 . ? 45.573 54.651 -18.176 1.00 14.48 ? 943 HOH B O 1 HETATM 9358 O O . HOH CA 10 . ? 36.198 31.553 -5.723 1.00 14.34 ? 944 HOH B O 1 HETATM 9359 O O . HOH CA 10 . ? 11.810 49.337 9.387 1.00 16.78 ? 945 HOH B O 1 HETATM 9360 O O . HOH CA 10 . ? 8.549 34.300 -18.035 1.00 25.28 ? 946 HOH B O 1 HETATM 9361 O O . HOH CA 10 . ? 49.773 45.432 -26.465 1.00 17.94 ? 947 HOH B O 1 HETATM 9362 O O . HOH CA 10 . ? 31.736 24.901 -19.895 1.00 20.70 ? 948 HOH B O 1 HETATM 9363 O O . HOH CA 10 . ? 25.366 30.626 -0.588 1.00 21.95 ? 949 HOH B O 1 HETATM 9364 O O . HOH CA 10 . ? 53.747 22.707 -4.202 1.00 16.77 ? 950 HOH B O 1 HETATM 9365 O O . HOH CA 10 . ? 51.960 28.959 8.335 1.00 16.77 ? 951 HOH B O 1 HETATM 9366 O O . HOH CA 10 . ? 14.557 41.089 -18.864 1.00 16.87 ? 952 HOH B O 1 HETATM 9367 O O . HOH CA 10 . ? 31.044 53.346 -21.273 1.00 19.09 ? 953 HOH B O 1 HETATM 9368 O O . HOH CA 10 . ? 29.921 34.996 -26.840 1.00 17.57 ? 954 HOH B O 1 HETATM 9369 O O . HOH CA 10 . ? 62.068 39.045 -31.518 1.00 25.01 ? 955 HOH B O 1 HETATM 9370 O O . HOH CA 10 . ? 27.094 48.156 8.972 1.00 19.32 ? 956 HOH B O 1 HETATM 9371 O O . HOH CA 10 . ? 55.222 44.717 -24.979 1.00 15.42 ? 957 HOH B O 1 HETATM 9372 O O . HOH CA 10 . ? 11.542 49.227 0.108 1.00 24.88 ? 958 HOH B O 1 HETATM 9373 O O . HOH CA 10 . ? 58.253 44.752 -29.015 1.00 17.18 ? 959 HOH B O 1 HETATM 9374 O O . HOH CA 10 . ? 20.121 33.164 3.809 1.00 20.66 ? 960 HOH B O 1 HETATM 9375 O O . HOH CA 10 . ? 52.745 50.300 4.620 1.00 20.70 ? 961 HOH B O 1 HETATM 9376 O O . HOH CA 10 . ? 18.692 30.018 -15.379 1.00 18.28 ? 962 HOH B O 1 HETATM 9377 O O . HOH CA 10 . ? 77.549 40.152 -6.907 1.00 15.07 ? 963 HOH B O 1 HETATM 9378 O O . HOH CA 10 . ? 48.266 39.377 7.996 1.00 16.72 ? 964 HOH B O 1 HETATM 9379 O O . HOH CA 10 . ? 15.227 45.092 -17.630 1.00 17.35 ? 965 HOH B O 1 HETATM 9380 O O . HOH CA 10 . ? 38.823 52.611 -26.922 1.00 20.77 ? 966 HOH B O 1 HETATM 9381 O O . HOH CA 10 . ? 24.145 35.737 -24.167 1.00 13.19 ? 967 HOH B O 1 HETATM 9382 O O . HOH CA 10 . ? 25.837 32.233 -24.199 1.00 16.16 ? 968 HOH B O 1 HETATM 9383 O O . HOH CA 10 . ? 20.363 28.185 -16.796 1.00 19.30 ? 969 HOH B O 1 HETATM 9384 O O . HOH CA 10 . ? 40.730 52.694 4.269 1.00 17.15 ? 970 HOH B O 1 HETATM 9385 O O . HOH CA 10 . ? 41.879 55.010 -26.093 1.00 20.80 ? 971 HOH B O 1 HETATM 9386 O O . HOH CA 10 . ? 32.407 29.245 3.326 1.00 18.29 ? 972 HOH B O 1 HETATM 9387 O O . HOH CA 10 . ? 16.919 35.846 -3.867 1.00 16.11 ? 973 HOH B O 1 HETATM 9388 O O . HOH CA 10 . ? 47.228 31.044 -11.167 1.00 16.36 ? 974 HOH B O 1 HETATM 9389 O O . HOH CA 10 . ? 12.138 46.003 3.619 1.00 22.69 ? 975 HOH B O 1 HETATM 9390 O O . HOH CA 10 . ? 37.197 43.844 -9.017 1.00 22.35 ? 976 HOH B O 1 HETATM 9391 O O . HOH CA 10 . ? 34.782 58.566 -6.877 1.00 23.18 ? 977 HOH B O 1 HETATM 9392 O O . HOH CA 10 . ? 43.161 35.219 7.554 1.00 19.33 ? 978 HOH B O 1 HETATM 9393 O O . HOH CA 10 . ? 43.324 46.028 -27.905 1.00 20.44 ? 979 HOH B O 1 HETATM 9394 O O . HOH CA 10 . ? 9.595 31.748 -13.450 1.00 16.30 ? 980 HOH B O 1 HETATM 9395 O O . HOH CA 10 . ? 9.788 44.514 -7.359 1.00 24.04 ? 981 HOH B O 1 HETATM 9396 O O . HOH CA 10 . ? 60.641 57.730 -10.790 1.00 26.36 ? 982 HOH B O 1 HETATM 9397 O O . HOH CA 10 . ? 41.797 22.477 -0.117 1.00 21.06 ? 983 HOH B O 1 HETATM 9398 O O . HOH CA 10 . ? 57.741 38.017 -31.353 1.00 21.84 ? 984 HOH B O 1 HETATM 9399 O O . HOH CA 10 . ? 9.198 37.813 -18.943 1.00 25.01 ? 985 HOH B O 1 HETATM 9400 O O . HOH CA 10 . ? 73.669 29.643 -9.758 1.00 17.69 ? 986 HOH B O 1 HETATM 9401 O O . HOH CA 10 . ? 55.715 26.045 -38.374 1.00 20.34 ? 987 HOH B O 1 HETATM 9402 O O . HOH CA 10 . ? 64.410 48.254 -2.182 1.00 16.35 ? 988 HOH B O 1 HETATM 9403 O O . HOH CA 10 . ? 30.366 53.496 9.023 1.00 25.21 ? 989 HOH B O 1 HETATM 9404 O O . HOH CA 10 . ? 21.731 29.193 -8.851 1.00 25.11 ? 990 HOH B O 1 HETATM 9405 O O . HOH CA 10 . ? 38.161 30.046 3.011 1.00 18.64 ? 991 HOH B O 1 HETATM 9406 O O . HOH CA 10 . ? 69.646 37.879 0.610 1.00 18.48 ? 992 HOH B O 1 HETATM 9407 O O . HOH CA 10 . ? 70.826 45.009 -8.229 1.00 20.41 ? 993 HOH B O 1 HETATM 9408 O O . HOH CA 10 . ? 47.222 57.298 -15.170 1.00 15.76 ? 994 HOH B O 1 HETATM 9409 O O . HOH CA 10 . ? 47.213 49.587 -26.379 1.00 21.01 ? 995 HOH B O 1 HETATM 9410 O O . HOH CA 10 . ? 32.278 30.961 -29.643 1.00 28.35 ? 996 HOH B O 1 HETATM 9411 O O . HOH CA 10 . ? 16.588 47.646 -10.811 1.00 17.84 ? 997 HOH B O 1 HETATM 9412 O O . HOH CA 10 . ? 69.340 26.621 -17.201 1.00 17.08 ? 998 HOH B O 1 HETATM 9413 O O . HOH CA 10 . ? 74.785 41.585 -9.687 1.00 20.04 ? 999 HOH B O 1 HETATM 9414 O O . HOH CA 10 . ? 56.209 18.791 -31.327 1.00 16.25 ? 1000 HOH B O 1 HETATM 9415 O O . HOH CA 10 . ? 16.914 31.459 -8.940 1.00 17.08 ? 1001 HOH B O 1 HETATM 9416 O O . HOH CA 10 . ? 40.882 24.149 -7.490 1.00 18.08 ? 1002 HOH B O 1 HETATM 9417 O O . HOH CA 10 . ? 62.100 23.893 -14.942 1.00 20.13 ? 1003 HOH B O 1 HETATM 9418 O O . HOH CA 10 . ? 45.422 30.500 -38.489 1.00 17.88 ? 1004 HOH B O 1 HETATM 9419 O O . HOH CA 10 . ? 50.303 19.464 -18.472 1.00 18.36 ? 1005 HOH B O 1 HETATM 9420 O O . HOH CA 10 . ? 57.838 47.948 0.869 1.00 18.63 ? 1006 HOH B O 1 HETATM 9421 O O . HOH CA 10 . ? 25.295 24.005 -19.864 1.00 18.73 ? 1007 HOH B O 1 HETATM 9422 O O . HOH CA 10 . ? 21.608 55.108 5.802 1.00 20.93 ? 1008 HOH B O 1 HETATM 9423 O O . HOH CA 10 . ? 59.067 54.854 -16.268 1.00 21.64 ? 1009 HOH B O 1 HETATM 9424 O O . HOH CA 10 . ? 56.112 39.704 7.472 1.00 23.11 ? 1010 HOH B O 1 HETATM 9425 O O . HOH CA 10 . ? 18.291 39.251 -26.210 1.00 18.51 ? 1011 HOH B O 1 HETATM 9426 O O . HOH CA 10 . ? 52.678 18.627 -25.580 1.00 16.73 ? 1012 HOH B O 1 HETATM 9427 O O . HOH CA 10 . ? 63.684 55.558 -4.314 1.00 20.91 ? 1013 HOH B O 1 HETATM 9428 O O . HOH CA 10 . ? 29.367 32.278 -27.056 1.00 17.08 ? 1014 HOH B O 1 HETATM 9429 O O . HOH CA 10 . ? 58.834 33.971 4.863 1.00 17.96 ? 1015 HOH B O 1 HETATM 9430 O O . HOH CA 10 . ? 32.515 40.121 -3.653 1.00 19.24 ? 1016 HOH B O 1 HETATM 9431 O O . HOH CA 10 . ? 25.253 41.671 -23.593 1.00 18.25 ? 1017 HOH B O 1 HETATM 9432 O O . HOH CA 10 . ? 36.113 41.381 13.472 1.00 22.14 ? 1018 HOH B O 1 HETATM 9433 O O . HOH CA 10 . ? 12.775 47.160 -11.588 1.00 17.44 ? 1019 HOH B O 1 HETATM 9434 O O . HOH CA 10 . ? 52.187 34.172 -41.594 1.00 21.94 ? 1020 HOH B O 1 HETATM 9435 O O . HOH CA 10 . ? 24.595 32.657 3.233 1.00 21.18 ? 1021 HOH B O 1 HETATM 9436 O O . HOH CA 10 . ? 57.363 18.872 -16.689 1.00 21.07 ? 1022 HOH B O 1 HETATM 9437 O O . HOH CA 10 . ? 45.598 33.870 -35.112 1.00 23.71 ? 1023 HOH B O 1 HETATM 9438 O O . HOH CA 10 . ? 60.061 55.709 -1.343 1.00 21.63 ? 1024 HOH B O 1 HETATM 9439 O O . HOH CA 10 . ? 66.867 49.315 -2.760 1.00 18.43 ? 1025 HOH B O 1 HETATM 9440 O O . HOH CA 10 . ? 53.615 39.644 -39.119 1.00 19.79 ? 1026 HOH B O 1 HETATM 9441 O O . HOH CA 10 . ? 74.661 39.913 -3.202 1.00 21.91 ? 1027 HOH B O 1 HETATM 9442 O O . HOH CA 10 . ? 58.822 57.400 -14.434 1.00 33.19 ? 1028 HOH B O 1 HETATM 9443 O O . HOH CA 10 . ? 57.786 24.117 -37.620 1.00 29.73 ? 1029 HOH B O 1 HETATM 9444 O O . HOH CA 10 . ? 11.482 42.405 -3.630 1.00 19.33 ? 1030 HOH B O 1 HETATM 9445 O O . HOH CA 10 . ? 74.064 38.999 -13.724 1.00 21.48 ? 1031 HOH B O 1 HETATM 9446 O O . HOH CA 10 . ? 37.984 56.687 -8.593 1.00 20.16 ? 1032 HOH B O 1 HETATM 9447 O O . HOH CA 10 . ? 67.854 22.192 -9.092 1.00 22.05 ? 1033 HOH B O 1 HETATM 9448 O O . HOH CA 10 . ? 12.713 35.257 -6.158 1.00 22.14 ? 1034 HOH B O 1 HETATM 9449 O O . HOH CA 10 . ? 61.463 30.398 -29.864 1.00 21.29 ? 1035 HOH B O 1 HETATM 9450 O O . HOH CA 10 . ? 46.442 47.322 -27.285 1.00 18.74 ? 1036 HOH B O 1 HETATM 9451 O O . HOH CA 10 . ? 10.582 31.735 -9.706 1.00 22.76 ? 1037 HOH B O 1 HETATM 9452 O O . HOH CA 10 . ? 50.222 21.172 3.933 1.00 22.35 ? 1038 HOH B O 1 HETATM 9453 O O . HOH CA 10 . ? 44.365 22.993 -29.562 1.00 17.02 ? 1039 HOH B O 1 HETATM 9454 O O . HOH CA 10 . ? 71.335 45.145 -30.018 1.00 26.05 ? 1040 HOH B O 1 HETATM 9455 O O . HOH CA 10 . ? 47.442 51.679 9.220 1.00 23.40 ? 1041 HOH B O 1 HETATM 9456 O O . HOH CA 10 . ? 75.359 31.856 -11.342 1.00 23.34 ? 1042 HOH B O 1 HETATM 9457 O O . HOH CA 10 . ? 16.980 52.948 -16.157 1.00 30.00 ? 1043 HOH B O 1 HETATM 9458 O O . HOH CA 10 . ? 48.871 42.018 11.471 1.00 27.14 ? 1044 HOH B O 1 HETATM 9459 O O . HOH CA 10 . ? 24.639 63.084 -5.800 1.00 21.03 ? 1045 HOH B O 1 HETATM 9460 O O . HOH CA 10 . ? 22.687 60.714 -7.119 1.00 20.68 ? 1046 HOH B O 1 HETATM 9461 O O . HOH CA 10 . ? 68.834 26.949 -19.825 1.00 25.19 ? 1047 HOH B O 1 HETATM 9462 O O . HOH CA 10 . ? 73.758 35.046 -6.195 1.00 18.68 ? 1048 HOH B O 1 HETATM 9463 O O . HOH CA 10 . ? 28.080 35.117 -24.897 1.00 17.84 ? 1049 HOH B O 1 HETATM 9464 O O . HOH CA 10 . ? 55.354 48.942 1.386 1.00 17.82 ? 1050 HOH B O 1 HETATM 9465 O O . HOH CA 10 . ? 70.856 27.358 -3.124 1.00 24.06 ? 1051 HOH B O 1 HETATM 9466 O O . HOH CA 10 . ? 43.302 22.908 -11.854 1.00 23.26 ? 1052 HOH B O 1 HETATM 9467 O O . HOH CA 10 . ? 59.015 31.364 -40.251 1.00 26.90 ? 1053 HOH B O 1 HETATM 9468 O O . HOH CA 10 . ? 24.404 26.938 -24.071 1.00 21.93 ? 1054 HOH B O 1 HETATM 9469 O O . HOH CA 10 . ? 51.848 42.711 -37.222 1.00 20.39 ? 1055 HOH B O 1 HETATM 9470 O O . HOH CA 10 . ? 31.811 41.045 -5.991 1.00 20.89 ? 1056 HOH B O 1 HETATM 9471 O O . HOH CA 10 . ? 45.197 59.291 -1.207 1.00 20.33 ? 1057 HOH B O 1 HETATM 9472 O O . HOH CA 10 . ? 46.499 40.342 -16.175 1.00 8.90 ? 1058 HOH B O 1 HETATM 9473 O O . HOH CA 10 . ? 18.497 33.470 5.954 1.00 16.98 ? 1059 HOH B O 1 HETATM 9474 O O . HOH CA 10 . ? 4.140 40.937 -11.859 1.00 17.41 ? 1060 HOH B O 1 HETATM 9475 O O . HOH CA 10 . ? 24.701 31.331 8.792 1.00 16.81 ? 1061 HOH B O 1 HETATM 9476 O O . HOH CA 10 . ? 33.806 53.038 -22.133 1.00 16.09 ? 1062 HOH B O 1 HETATM 9477 O O . HOH CA 10 . ? 14.370 36.764 -4.593 1.00 21.83 ? 1063 HOH B O 1 HETATM 9478 O O . HOH CA 10 . ? 28.044 37.934 -23.948 1.00 15.03 ? 1064 HOH B O 1 HETATM 9479 O O . HOH CA 10 . ? 53.821 47.119 -24.659 1.00 17.99 ? 1065 HOH B O 1 HETATM 9480 O O . HOH CA 10 . ? 20.484 33.025 -3.079 1.00 21.42 ? 1066 HOH B O 1 HETATM 9481 O O . HOH CA 10 . ? 25.767 34.843 -26.088 1.00 19.32 ? 1067 HOH B O 1 HETATM 9482 O O . HOH CA 10 . ? 16.573 43.021 -19.033 1.00 17.62 ? 1068 HOH B O 1 HETATM 9483 O O . HOH CA 10 . ? 46.787 36.806 -39.033 1.00 19.01 ? 1069 HOH B O 1 HETATM 9484 O O . HOH CA 10 . ? 18.801 50.482 8.578 1.00 20.90 ? 1070 HOH B O 1 HETATM 9485 O O . HOH CA 10 . ? 12.996 43.030 -17.577 1.00 23.08 ? 1071 HOH B O 1 HETATM 9486 O O . HOH CA 10 . ? 40.798 23.526 -10.616 1.00 19.64 ? 1072 HOH B O 1 HETATM 9487 O O . HOH CA 10 . ? 30.359 26.963 -10.610 1.00 24.58 ? 1073 HOH B O 1 HETATM 9488 O O . HOH CA 10 . ? 13.102 40.117 -3.445 1.00 21.70 ? 1074 HOH B O 1 HETATM 9489 O O . HOH CA 10 . ? 17.632 32.088 -6.171 1.00 16.21 ? 1075 HOH B O 1 HETATM 9490 O O . HOH CA 10 . ? 12.626 40.457 -20.631 1.00 24.62 ? 1076 HOH B O 1 HETATM 9491 O O . HOH CA 10 . ? 42.713 58.760 -2.609 1.00 19.80 ? 1077 HOH B O 1 HETATM 9492 O O . HOH CA 10 . ? 50.470 18.855 -24.004 1.00 21.92 ? 1078 HOH B O 1 HETATM 9493 O O . HOH CA 10 . ? 54.730 52.587 -20.717 1.00 23.78 ? 1079 HOH B O 1 HETATM 9494 O O . HOH CA 10 . ? 13.056 32.621 -6.801 1.00 21.27 ? 1080 HOH B O 1 HETATM 9495 O O . HOH CA 10 . ? 25.758 50.390 10.391 1.00 21.22 ? 1081 HOH B O 1 HETATM 9496 O O . HOH CA 10 . ? 16.920 36.204 2.344 1.00 24.75 ? 1082 HOH B O 1 HETATM 9497 O O . HOH CA 10 . ? 45.351 49.930 8.946 1.00 24.49 ? 1083 HOH B O 1 HETATM 9498 O O . HOH CA 10 . ? 37.149 27.475 -26.971 1.00 29.00 ? 1084 HOH B O 1 HETATM 9499 O O . HOH CA 10 . ? 53.792 48.280 7.458 1.00 17.30 ? 1085 HOH B O 1 HETATM 9500 O O . HOH CA 10 . ? 59.223 31.997 -33.069 1.00 22.31 ? 1086 HOH B O 1 HETATM 9501 O O . HOH CA 10 . ? 17.927 43.857 -21.401 1.00 22.79 ? 1087 HOH B O 1 HETATM 9502 O O . HOH CA 10 . ? 21.283 33.756 0.701 1.00 34.13 ? 1088 HOH B O 1 HETATM 9503 O O . HOH CA 10 . ? 54.741 60.155 -17.799 1.00 27.51 ? 1089 HOH B O 1 HETATM 9504 O O . HOH CA 10 . ? 62.724 33.928 2.700 1.00 24.34 ? 1090 HOH B O 1 HETATM 9505 O O . HOH CA 10 . ? 17.495 29.722 -12.995 1.00 26.31 ? 1091 HOH B O 1 HETATM 9506 O O . HOH CA 10 . ? 24.849 46.050 -21.671 1.00 23.99 ? 1092 HOH B O 1 HETATM 9507 O O . HOH CA 10 . ? 43.597 39.438 9.397 1.00 23.59 ? 1093 HOH B O 1 HETATM 9508 O O . HOH CA 10 . ? 45.909 46.621 11.309 1.00 22.96 ? 1094 HOH B O 1 HETATM 9509 O O . HOH CA 10 . ? 61.895 38.057 2.183 1.00 26.70 ? 1095 HOH B O 1 HETATM 9510 O O . HOH CA 10 . ? 65.167 47.870 -34.563 1.00 23.30 ? 1096 HOH B O 1 HETATM 9511 O O . HOH CA 10 . ? 29.765 34.589 12.944 1.00 25.26 ? 1097 HOH B O 1 HETATM 9512 O O . HOH CA 10 . ? 48.218 24.259 -40.478 1.00 20.11 ? 1098 HOH B O 1 HETATM 9513 O O . HOH CA 10 . ? 58.068 27.063 5.169 1.00 25.33 ? 1099 HOH B O 1 HETATM 9514 O O . HOH CA 10 . ? 24.425 57.935 3.212 1.00 23.60 ? 1100 HOH B O 1 HETATM 9515 O O . HOH CA 10 . ? 58.425 32.338 -42.824 1.00 18.54 ? 1101 HOH B O 1 HETATM 9516 O O . HOH CA 10 . ? 68.610 44.386 -0.194 1.00 26.14 ? 1102 HOH B O 1 HETATM 9517 O O . HOH CA 10 . ? 60.501 29.698 3.772 1.00 26.51 ? 1103 HOH B O 1 HETATM 9518 O O . HOH CA 10 . ? 30.327 38.129 -30.533 1.00 28.57 ? 1104 HOH B O 1 HETATM 9519 O O . HOH CA 10 . ? 45.467 24.259 -41.134 1.00 28.06 ? 1105 HOH B O 1 HETATM 9520 O O . HOH CA 10 . ? 34.725 24.613 -17.064 1.00 21.33 ? 1106 HOH B O 1 HETATM 9521 O O . HOH CA 10 . ? 26.233 54.259 7.347 1.00 23.70 ? 1107 HOH B O 1 HETATM 9522 O O . HOH CA 10 . ? 46.429 59.259 -22.970 1.00 23.99 ? 1108 HOH B O 1 HETATM 9523 O O . HOH CA 10 . ? 47.225 20.301 -1.629 1.00 28.11 ? 1109 HOH B O 1 HETATM 9524 O O . HOH CA 10 . ? 50.159 58.147 -3.258 1.00 28.12 ? 1110 HOH B O 1 HETATM 9525 O O . HOH CA 10 . ? 40.606 39.880 -35.166 1.00 24.99 ? 1111 HOH B O 1 HETATM 9526 O O . HOH CA 10 . ? 51.675 61.035 -16.395 1.00 26.66 ? 1112 HOH B O 1 HETATM 9527 O O . HOH CA 10 . ? 61.903 20.023 -16.902 1.00 27.44 ? 1113 HOH B O 1 HETATM 9528 O O . HOH CA 10 . ? 23.222 60.061 1.673 1.00 24.32 ? 1114 HOH B O 1 HETATM 9529 O O . HOH CA 10 . ? 36.745 56.416 1.859 1.00 28.90 ? 1115 HOH B O 1 HETATM 9530 O O . HOH CA 10 . ? 55.564 57.137 5.188 1.00 28.86 ? 1116 HOH B O 1 HETATM 9531 O O . HOH CA 10 . ? 57.126 45.270 -31.310 1.00 26.13 ? 1117 HOH B O 1 HETATM 9532 O O . HOH CA 10 . ? 64.360 29.480 -30.053 1.00 26.63 ? 1118 HOH B O 1 HETATM 9533 O O . HOH CA 10 . ? 12.788 38.064 -21.884 1.00 22.15 ? 1119 HOH B O 1 HETATM 9534 O O . HOH CA 10 . ? 51.573 58.477 -21.841 1.00 20.37 ? 1120 HOH B O 1 HETATM 9535 O O . HOH CA 10 . ? 8.726 41.647 -14.435 1.00 28.07 ? 1121 HOH B O 1 HETATM 9536 O O . HOH CA 10 . ? 54.471 48.237 4.528 1.00 24.18 ? 1122 HOH B O 1 HETATM 9537 O O . HOH CA 10 . ? 35.567 29.743 -28.306 1.00 31.08 ? 1123 HOH B O 1 HETATM 9538 O O . HOH CA 10 . ? 29.711 55.518 -21.914 1.00 19.34 ? 1124 HOH B O 1 HETATM 9539 O O . HOH CA 10 . ? 14.783 42.282 1.231 1.00 24.31 ? 1125 HOH B O 1 HETATM 9540 O O . HOH CA 10 . ? 15.085 52.361 6.528 1.00 25.51 ? 1126 HOH B O 1 HETATM 9541 O O . HOH CA 10 . ? 56.596 34.360 -41.843 1.00 19.15 ? 1127 HOH B O 1 HETATM 9542 O O . HOH CA 10 . ? 24.833 30.477 -3.889 1.00 19.68 ? 1128 HOH B O 1 HETATM 9543 O O . HOH CA 10 . ? 48.534 19.710 0.826 1.00 23.39 ? 1129 HOH B O 1 HETATM 9544 O O . HOH CA 10 . ? 60.088 23.324 -7.888 1.00 31.96 ? 1130 HOH B O 1 HETATM 9545 O O . HOH CA 10 . ? 54.031 20.503 -1.514 1.00 28.14 ? 1131 HOH B O 1 HETATM 9546 O O . HOH CA 10 . ? 59.657 29.442 -33.045 1.00 21.43 ? 1132 HOH B O 1 HETATM 9547 O O . HOH CA 10 . ? 72.029 42.769 -9.261 1.00 22.23 ? 1133 HOH B O 1 HETATM 9548 O O . HOH CA 10 . ? 11.494 43.451 4.976 1.00 28.97 ? 1134 HOH B O 1 HETATM 9549 O O . HOH CA 10 . ? 21.573 50.931 7.233 1.00 22.12 ? 1135 HOH B O 1 HETATM 9550 O O . HOH CA 10 . ? 28.253 40.117 -29.585 1.00 31.28 ? 1136 HOH B O 1 HETATM 9551 O O . HOH CA 10 . ? 55.295 56.463 -20.001 1.00 32.85 ? 1137 HOH B O 1 HETATM 9552 O O . HOH CA 10 . ? 70.617 30.190 -26.610 1.00 33.08 ? 1138 HOH B O 1 HETATM 9553 O O . HOH CA 10 . ? 76.485 28.615 -16.190 1.00 28.25 ? 1139 HOH B O 1 HETATM 9554 O O . HOH CA 10 . ? 50.320 48.109 -30.771 1.00 28.19 ? 1140 HOH B O 1 HETATM 9555 O O . HOH CA 10 . ? 75.485 36.239 -4.567 1.00 24.61 ? 1141 HOH B O 1 HETATM 9556 O O . HOH CA 10 . ? 22.133 63.229 -4.892 1.00 27.92 ? 1142 HOH B O 1 HETATM 9557 O O . HOH CA 10 . ? 77.355 38.107 -5.145 1.00 26.01 ? 1143 HOH B O 1 HETATM 9558 O O . HOH CA 10 . ? 66.186 32.738 1.112 1.00 25.15 ? 1144 HOH B O 1 HETATM 9559 O O . HOH CA 10 . ? 73.636 27.371 -5.759 1.00 27.32 ? 1145 HOH B O 1 HETATM 9560 O O . HOH CA 10 . ? 18.012 29.413 -20.921 1.00 25.37 ? 1146 HOH B O 1 HETATM 9561 O O . HOH CA 10 . ? 23.706 22.805 -21.681 1.00 28.79 ? 1147 HOH B O 1 HETATM 9562 O O . HOH CA 10 . ? 37.611 56.878 -25.114 1.00 39.93 ? 1148 HOH B O 1 HETATM 9563 O O . HOH CA 10 . ? 78.443 42.276 -5.552 1.00 17.32 ? 1149 HOH B O 1 HETATM 9564 O O . HOH CA 10 . ? 47.815 47.815 -31.798 1.00 28.69 ? 1150 HOH B O 1 HETATM 9565 O O . HOH CA 10 . ? 10.134 44.698 -15.533 1.00 26.17 ? 1151 HOH B O 1 HETATM 9566 O O . HOH CA 10 . ? 31.737 51.153 11.341 1.00 25.54 ? 1152 HOH B O 1 HETATM 9567 O O . HOH CA 10 . ? 48.171 59.133 -0.965 1.00 23.76 ? 1153 HOH B O 1 HETATM 9568 O O . HOH CA 10 . ? 45.267 29.001 -28.497 1.00 19.62 ? 1154 HOH B O 1 HETATM 9569 O O . HOH CA 10 . ? 60.690 22.176 -4.338 1.00 23.51 ? 1155 HOH B O 1 HETATM 9570 O O . HOH CA 10 . ? 51.931 49.580 -27.024 1.00 23.59 ? 1156 HOH B O 1 HETATM 9571 O O . HOH CA 10 . ? 73.574 39.505 -31.749 1.00 25.68 ? 1157 HOH B O 1 HETATM 9572 O O . HOH CA 10 . ? 57.328 54.113 2.454 1.00 26.09 ? 1158 HOH B O 1 HETATM 9573 O O . HOH CA 10 . ? 34.902 61.709 -13.825 1.00 26.81 ? 1159 HOH B O 1 HETATM 9574 O O . HOH CA 10 . ? 57.645 48.173 -24.000 1.00 25.21 ? 1160 HOH B O 1 HETATM 9575 O O . HOH CA 10 . ? 38.535 51.589 -6.187 1.00 19.94 ? 1161 HOH B O 1 HETATM 9576 O O . HOH CA 10 . ? 49.445 60.781 -6.853 1.00 29.91 ? 1162 HOH B O 1 HETATM 9577 O O . HOH CA 10 . ? 25.511 34.086 1.125 1.00 28.08 ? 1163 HOH B O 1 HETATM 9578 O O . HOH CA 10 . ? 63.680 55.881 -26.740 1.00 30.44 ? 1164 HOH B O 1 HETATM 9579 O O . HOH CA 10 . ? 34.812 49.301 -27.449 1.00 21.89 ? 1165 HOH B O 1 HETATM 9580 O O . HOH CA 10 . ? 62.250 54.693 -22.680 1.00 31.39 ? 1166 HOH B O 1 HETATM 9581 O O . HOH CA 10 . ? 41.503 54.761 2.412 1.00 33.08 ? 1167 HOH B O 1 HETATM 9582 O O . HOH CA 10 . ? 54.789 26.315 -42.131 1.00 32.42 ? 1168 HOH B O 1 HETATM 9583 O O . HOH CA 10 . ? 35.791 29.223 -4.259 1.00 21.54 ? 1169 HOH B O 1 HETATM 9584 O O . HOH CA 10 . ? 34.903 44.380 -6.897 1.00 30.06 ? 1170 HOH B O 1 HETATM 9585 O O . HOH CA 10 . ? 62.075 49.245 1.862 1.00 30.68 ? 1171 HOH B O 1 HETATM 9586 O O . HOH CA 10 . ? 29.873 45.963 -25.418 1.00 22.89 ? 1172 HOH B O 1 HETATM 9587 O O . HOH CA 10 . ? 51.395 19.038 -20.923 1.00 25.70 ? 1173 HOH B O 1 HETATM 9588 O O . HOH CA 10 . ? 74.597 28.188 -11.969 1.00 25.91 ? 1174 HOH B O 1 HETATM 9589 O O . HOH CA 10 . ? 57.416 23.030 0.225 1.00 25.44 ? 1175 HOH B O 1 HETATM 9590 O O . HOH CA 10 . ? 60.102 48.811 -25.309 1.00 26.30 ? 1176 HOH B O 1 HETATM 9591 O O . HOH CA 10 . ? 64.240 48.247 0.877 1.00 32.58 ? 1177 HOH B O 1 HETATM 9592 O O . HOH CA 10 . ? 64.115 21.942 -16.086 1.00 34.50 ? 1178 HOH B O 1 HETATM 9593 O O . HOH CA 10 . ? 30.176 29.396 -27.363 1.00 33.19 ? 1179 HOH B O 1 HETATM 9594 O O . HOH CA 10 . ? 39.292 21.236 -3.829 1.00 27.97 ? 1180 HOH B O 1 HETATM 9595 O O . HOH CA 10 . ? 61.836 54.921 -16.289 1.00 27.06 ? 1181 HOH B O 1 HETATM 9596 O O . HOH CA 10 . ? 37.513 31.401 -28.724 1.00 29.67 ? 1182 HOH B O 1 HETATM 9597 O O . HOH CA 10 . ? 77.190 39.457 -2.541 1.00 34.07 ? 1183 HOH B O 1 HETATM 9598 O O . HOH CA 10 . ? 10.561 31.500 -6.970 1.00 30.59 ? 1184 HOH B O 1 HETATM 9599 O O . HOH CA 10 . ? 43.424 50.456 10.882 1.00 33.04 ? 1185 HOH B O 1 HETATM 9600 O O . HOH CA 10 . ? 23.910 33.185 -27.169 1.00 23.79 ? 1186 HOH B O 1 HETATM 9601 O O . HOH CA 10 . ? 71.496 30.213 -21.445 1.00 30.48 ? 1187 HOH B O 1 HETATM 9602 O O . HOH CA 10 . ? 54.199 50.049 -24.347 1.00 29.19 ? 1188 HOH B O 1 HETATM 9603 O O . HOH CA 10 . ? 74.108 25.795 -8.224 1.00 32.64 ? 1189 HOH B O 1 HETATM 9604 O O . HOH CA 10 . ? 11.929 55.375 0.416 1.00 28.76 ? 1190 HOH B O 1 HETATM 9605 O O . HOH CA 10 . ? 56.701 57.462 -1.808 1.00 29.60 ? 1191 HOH B O 1 HETATM 9606 O O . HOH CA 10 . ? 26.431 30.298 5.451 1.00 27.97 ? 1192 HOH B O 1 HETATM 9607 O O . HOH CA 10 . ? 74.075 40.272 -0.576 1.00 32.52 ? 1193 HOH B O 1 HETATM 9608 O O . HOH CA 10 . ? 17.597 52.542 7.416 1.00 33.59 ? 1194 HOH B O 1 HETATM 9609 O O . HOH CA 10 . ? 39.786 62.143 -16.516 1.00 34.04 ? 1195 HOH B O 1 HETATM 9610 O O . HOH CA 10 . ? 46.161 39.123 9.858 1.00 35.66 ? 1196 HOH B O 1 HETATM 9611 O O . HOH CA 10 . ? 56.011 23.400 5.426 1.00 29.23 ? 1197 HOH B O 1 HETATM 9612 O O . HOH CA 10 . ? 65.863 24.218 -9.236 1.00 32.16 ? 1198 HOH B O 1 HETATM 9613 O O . HOH CA 10 . ? 66.617 53.294 -2.847 1.00 26.01 ? 1199 HOH B O 1 HETATM 9614 O O . HOH CA 10 . ? 10.192 46.998 6.893 1.00 27.77 ? 1200 HOH B O 1 HETATM 9615 O O . HOH CA 10 . ? 60.457 49.485 -29.515 1.00 34.04 ? 1201 HOH B O 1 HETATM 9616 O O . HOH CA 10 . ? 51.585 36.611 -40.728 1.00 32.61 ? 1202 HOH B O 1 HETATM 9617 O O . HOH CA 10 . ? 39.577 58.937 -10.533 1.00 28.30 ? 1203 HOH B O 1 HETATM 9618 O O . HOH CA 10 . ? 74.884 44.051 -8.452 1.00 35.60 ? 1204 HOH B O 1 HETATM 9619 O O . HOH CA 10 . ? 49.267 37.399 -39.861 1.00 31.34 ? 1205 HOH B O 1 HETATM 9620 O O . HOH CA 10 . ? 54.162 53.009 8.460 1.00 31.76 ? 1206 HOH B O 1 HETATM 9621 O O . HOH CA 10 . ? 45.082 17.268 -27.076 1.00 32.35 ? 1207 HOH B O 1 HETATM 9622 O O . HOH CA 10 . ? 34.867 42.289 -30.490 1.00 32.62 ? 1208 HOH B O 1 HETATM 9623 O O . HOH CA 10 . ? 36.687 59.937 -5.247 1.00 29.81 ? 1209 HOH B O 1 HETATM 9624 O O . HOH CA 10 . ? 66.435 19.359 -6.395 1.00 33.36 ? 1210 HOH B O 1 HETATM 9625 O O . HOH CA 10 . ? 64.174 24.561 -30.545 1.00 25.72 ? 1211 HOH B O 1 HETATM 9626 O O . HOH CA 10 . ? 12.230 46.192 -15.389 1.00 24.03 ? 1212 HOH B O 1 HETATM 9627 O O . HOH CA 10 . ? 44.353 49.221 -26.704 1.00 29.09 ? 1213 HOH B O 1 HETATM 9628 O O . HOH CA 10 . ? 69.926 41.857 -20.781 1.00 25.02 ? 1214 HOH B O 1 HETATM 9629 O O . HOH CA 10 . ? 48.504 18.577 -12.219 1.00 30.86 ? 1215 HOH B O 1 HETATM 9630 O O . HOH CA 10 . ? 47.637 50.932 -28.725 1.00 31.08 ? 1216 HOH B O 1 HETATM 9631 O O . HOH CA 10 . ? 52.636 45.129 -36.491 1.00 29.52 ? 1217 HOH B O 1 HETATM 9632 O O . HOH CA 10 . ? 19.276 59.433 -0.546 1.00 33.77 ? 1218 HOH B O 1 HETATM 9633 O O . HOH CA 10 . ? 56.900 35.471 -35.591 1.00 29.22 ? 1219 HOH B O 1 HETATM 9634 O O . HOH CA 10 . ? 14.753 54.588 -12.649 1.00 23.53 ? 1220 HOH B O 1 HETATM 9635 O O . HOH CA 10 . ? 28.218 60.264 3.670 1.00 33.72 ? 1221 HOH B O 1 HETATM 9636 O O . HOH CA 10 . ? 42.053 21.831 -28.500 1.00 24.01 ? 1222 HOH B O 1 HETATM 9637 O O . HOH CA 10 . ? 38.673 54.203 -5.649 1.00 27.84 ? 1223 HOH B O 1 HETATM 9638 O O . HOH CA 10 . ? 65.081 43.548 1.489 1.00 30.57 ? 1224 HOH B O 1 HETATM 9639 O O . HOH CA 10 . ? 44.066 25.254 -31.523 1.00 31.59 ? 1225 HOH B O 1 HETATM 9640 O O . HOH CA 10 . ? 66.637 19.685 -9.058 1.00 36.03 ? 1226 HOH B O 1 HETATM 9641 O O . HOH CA 10 . ? 18.086 57.371 -14.742 1.00 35.08 ? 1227 HOH B O 1 HETATM 9642 O O . HOH CA 10 . ? 10.833 52.450 -10.030 1.00 26.79 ? 1228 HOH B O 1 HETATM 9643 O O . HOH CA 10 . ? 43.711 20.911 -16.133 1.00 29.22 ? 1229 HOH B O 1 HETATM 9644 O O . HOH CA 10 . ? 28.563 29.317 6.706 1.00 27.71 ? 1230 HOH B O 1 HETATM 9645 O O . HOH CA 10 . ? 33.817 26.903 -24.897 1.00 27.18 ? 1231 HOH B O 1 HETATM 9646 O O . HOH CA 10 . ? 23.102 60.234 -14.272 1.00 38.32 ? 1232 HOH B O 1 HETATM 9647 O O . HOH CA 10 . ? 59.341 46.062 2.299 1.00 34.15 ? 1233 HOH B O 1 HETATM 9648 O O . HOH CA 10 . ? 67.828 53.784 -16.628 1.00 23.65 ? 1234 HOH B O 1 HETATM 9649 O O . HOH CA 10 . ? 71.269 23.979 -28.843 1.00 29.65 ? 1235 HOH B O 1 HETATM 9650 O O . HOH CA 10 . ? 10.184 32.441 -16.141 1.00 31.80 ? 1236 HOH B O 1 HETATM 9651 O O . HOH CA 10 . ? 52.566 27.257 -43.284 1.00 27.19 ? 1237 HOH B O 1 HETATM 9652 O O . HOH CA 10 . ? 11.004 36.506 -20.674 1.00 41.27 ? 1238 HOH B O 1 HETATM 9653 O O . HOH CA 10 . ? 10.619 36.094 -4.446 1.00 27.90 ? 1239 HOH B O 1 HETATM 9654 O O . HOH CA 10 . ? 77.787 31.396 -18.067 1.00 36.20 ? 1240 HOH B O 1 HETATM 9655 O O . HOH CA 10 . ? 73.296 24.791 -34.172 1.00 30.36 ? 1241 HOH B O 1 HETATM 9656 O O . HOH CA 10 . ? 45.213 43.746 -24.531 1.00 15.37 ? 1242 HOH B O 1 HETATM 9657 O O . HOH CA 10 . ? 64.322 27.245 -31.527 1.00 20.46 ? 1243 HOH B O 1 HETATM 9658 O O . HOH CA 10 . ? 62.340 27.949 -33.366 1.00 21.70 ? 1244 HOH B O 1 HETATM 9659 O O . HOH CA 10 . ? 32.875 22.184 -17.254 1.00 27.76 ? 1245 HOH B O 1 HETATM 9660 O O . HOH CA 10 . ? 25.112 51.936 8.053 1.00 24.24 ? 1246 HOH B O 1 HETATM 9661 O O . HOH CA 10 . ? 10.329 42.260 -16.818 1.00 25.40 ? 1247 HOH B O 1 HETATM 9662 O O . HOH CA 10 . ? 28.253 32.287 12.879 1.00 26.45 ? 1248 HOH B O 1 HETATM 9663 O O . HOH CA 10 . ? 32.488 22.318 -19.881 1.00 25.67 ? 1249 HOH B O 1 HETATM 9664 O O . HOH CA 10 . ? 7.378 39.490 -15.524 1.00 25.24 ? 1250 HOH B O 1 HETATM 9665 O O . HOH CA 10 . ? 50.308 24.500 -42.323 1.00 33.79 ? 1251 HOH B O 1 HETATM 9666 O O . HOH CA 10 . ? 12.725 29.682 -9.902 1.00 30.78 ? 1252 HOH B O 1 HETATM 9667 O O . HOH CA 10 . ? 36.243 44.402 -31.418 1.00 25.68 ? 1253 HOH B O 1 HETATM 9668 O O . HOH CA 10 . ? 50.351 50.345 -29.070 1.00 28.18 ? 1254 HOH B O 1 HETATM 9669 O O . HOH CA 10 . ? 63.335 19.048 -22.445 1.00 27.40 ? 1255 HOH B O 1 HETATM 9670 O O . HOH CA 10 . ? 33.403 28.999 5.946 1.00 30.31 ? 1256 HOH B O 1 HETATM 9671 O O . HOH CA 10 . ? 70.260 48.717 -5.511 1.00 25.37 ? 1257 HOH B O 1 HETATM 9672 O O . HOH CA 10 . ? 72.320 43.528 -0.256 1.00 32.16 ? 1258 HOH B O 1 HETATM 9673 O O . HOH CA 10 . ? 41.301 22.952 -26.153 1.00 31.56 ? 1259 HOH B O 1 HETATM 9674 O O . HOH CA 10 . ? 36.888 26.189 -7.740 1.00 27.75 ? 1260 HOH B O 1 HETATM 9675 O O . HOH CA 10 . ? 62.895 31.404 3.295 1.00 22.97 ? 1261 HOH B O 1 HETATM 9676 O O . HOH CA 10 . ? 31.580 49.805 -27.343 1.00 27.45 ? 1262 HOH B O 1 HETATM 9677 O O . HOH CA 10 . ? 27.542 54.105 9.533 1.00 27.09 ? 1263 HOH B O 1 HETATM 9678 O O . HOH CA 10 . ? 37.603 47.590 9.337 1.00 26.27 ? 1264 HOH B O 1 HETATM 9679 O O . HOH CA 10 . ? 70.875 23.907 -16.451 1.00 27.83 ? 1265 HOH B O 1 HETATM 9680 O O . HOH CA 10 . ? 33.153 44.420 11.716 1.00 35.02 ? 1266 HOH B O 1 HETATM 9681 O O . HOH CA 10 . ? 26.381 65.578 -5.224 1.00 31.00 ? 1267 HOH B O 1 HETATM 9682 O O . HOH CA 10 . ? 29.783 62.835 -2.286 1.00 29.15 ? 1268 HOH B O 1 HETATM 9683 O O . HOH CA 10 . ? 38.305 56.327 4.201 1.00 27.98 ? 1269 HOH B O 1 HETATM 9684 O O . HOH CA 10 . ? 14.828 46.703 -19.736 1.00 25.93 ? 1270 HOH B O 1 HETATM 9685 O O . HOH CA 10 . ? 71.104 32.310 -28.413 1.00 31.09 ? 1271 HOH B O 1 HETATM 9686 O O . HOH CA 10 . ? 33.120 26.015 -10.425 1.00 32.27 ? 1272 HOH B O 1 HETATM 9687 O O . HOH CA 10 . ? 62.047 27.437 2.544 1.00 34.95 ? 1273 HOH B O 1 HETATM 9688 O O . HOH CA 10 . ? 56.184 16.337 -17.373 1.00 30.97 ? 1274 HOH B O 1 HETATM 9689 O O . HOH CA 10 . ? 34.454 48.110 -29.817 1.00 29.39 ? 1275 HOH B O 1 HETATM 9690 O O . HOH CA 10 . ? 45.463 25.006 5.877 1.00 28.04 ? 1276 HOH B O 1 HETATM 9691 O O . HOH CA 10 . ? 31.616 19.628 -20.463 1.00 30.72 ? 1277 HOH B O 1 HETATM 9692 O O . HOH CA 10 . ? 27.473 45.362 -24.069 1.00 33.05 ? 1278 HOH B O 1 HETATM 9693 O O . HOH CA 10 . ? 43.456 29.226 -37.025 1.00 38.41 ? 1279 HOH B O 1 HETATM 9694 O O . HOH CA 10 . ? 47.029 20.695 3.470 1.00 32.77 ? 1280 HOH B O 1 HETATM 9695 O O . HOH CA 10 . ? 61.664 17.359 -24.187 1.00 33.50 ? 1281 HOH B O 1 HETATM 9696 O O . HOH CA 10 . ? 64.372 42.982 -35.515 1.00 31.54 ? 1282 HOH B O 1 HETATM 9697 O O . HOH CA 10 . ? 50.944 26.936 9.418 1.00 29.46 ? 1283 HOH B O 1 HETATM 9698 O O . HOH CA 10 . ? 75.197 31.346 -7.839 1.00 27.88 ? 1284 HOH B O 1 HETATM 9699 O O . HOH CA 10 . ? 13.556 54.663 5.975 1.00 28.46 ? 1285 HOH B O 1 HETATM 9700 O O . HOH CA 10 . ? 15.168 59.384 1.080 1.00 30.90 ? 1286 HOH B O 1 HETATM 9701 O O . HOH CA 10 . ? 76.934 29.245 -13.515 1.00 44.91 ? 1287 HOH B O 1 HETATM 9702 O O . HOH CA 10 . ? 24.683 23.125 -17.304 1.00 24.84 ? 1288 HOH B O 1 HETATM 9703 O O . HOH CA 10 . ? 54.778 60.730 -9.757 1.00 33.44 ? 1289 HOH B O 1 HETATM 9704 O O . HOH CA 10 . ? 43.628 23.044 -14.459 1.00 27.00 ? 1290 HOH B O 1 HETATM 9705 O O . HOH CA 10 . ? 40.063 33.814 13.786 1.00 47.47 ? 1291 HOH B O 1 HETATM 9706 O O . HOH CA 10 . ? 30.608 37.779 13.720 1.00 39.43 ? 1292 HOH B O 1 HETATM 9707 O O . HOH CA 10 . ? 75.629 26.029 -10.542 1.00 33.59 ? 1293 HOH B O 1 HETATM 9708 O O . HOH CA 10 . ? 35.812 54.789 -22.510 1.00 26.18 ? 1294 HOH B O 1 HETATM 9709 O O . HOH CA 10 . ? 9.951 40.495 -19.103 1.00 30.34 ? 1295 HOH B O 1 HETATM 9710 O O . HOH CA 10 . ? 36.348 27.273 3.224 1.00 38.59 ? 1296 HOH B O 1 HETATM 9711 O O . HOH CA 10 . ? 16.746 65.637 -0.455 1.00 36.11 ? 1297 HOH B O 1 HETATM 9712 O O . HOH CA 10 . ? 62.656 20.288 -3.587 1.00 32.10 ? 1298 HOH B O 1 HETATM 9713 O O . HOH CA 10 . ? 41.935 41.955 -29.152 1.00 29.72 ? 1299 HOH B O 1 HETATM 9714 O O . HOH CA 10 . ? 35.115 30.785 -31.299 1.00 45.64 ? 1300 HOH B O 1 HETATM 9715 O O . HOH CA 10 . ? 55.586 41.110 10.531 1.00 30.93 ? 1301 HOH B O 1 HETATM 9716 O O . HOH CA 10 . ? 22.246 31.052 6.806 1.00 27.19 ? 1302 HOH B O 1 HETATM 9717 O O . HOH CA 10 . ? 38.134 23.899 -7.760 1.00 32.09 ? 1303 HOH B O 1 HETATM 9718 O O . HOH CA 10 . ? 44.719 61.327 2.399 1.00 37.47 ? 1304 HOH B O 1 HETATM 9719 O O . HOH CA 10 . ? 51.512 33.025 12.244 1.00 37.24 ? 1305 HOH B O 1 HETATM 9720 O O . HOH CA 10 . ? 34.978 28.880 1.576 1.00 34.14 ? 1306 HOH B O 1 HETATM 9721 O O . HOH CA 10 . ? 37.401 32.650 -31.036 1.00 33.04 ? 1307 HOH B O 1 HETATM 9722 O O . HOH CA 10 . ? 15.279 42.476 -24.275 1.00 36.41 ? 1308 HOH B O 1 HETATM 9723 O O . HOH CA 10 . ? 37.104 33.082 9.734 1.00 39.13 ? 1309 HOH B O 1 HETATM 9724 O O . HOH CA 10 . ? 38.244 60.713 -7.561 1.00 38.17 ? 1310 HOH B O 1 HETATM 9725 O O . HOH CA 10 . ? 32.105 46.177 -29.418 1.00 28.74 ? 1311 HOH B O 1 HETATM 9726 O O . HOH CA 10 . ? 26.680 29.727 9.490 1.00 26.12 ? 1313 HOH B O 1 HETATM 9727 O O . HOH CA 10 . ? 18.752 27.846 -18.892 1.00 31.50 ? 1314 HOH B O 1 HETATM 9728 O O . HOH CA 10 . ? 32.252 55.686 9.121 1.00 38.03 ? 1315 HOH B O 1 HETATM 9729 O O . HOH CA 10 . ? 47.894 21.529 -40.211 1.00 34.42 ? 1316 HOH B O 1 HETATM 9730 O O . HOH CA 10 . ? 56.416 51.434 3.482 1.00 43.13 ? 1317 HOH B O 1 HETATM 9731 O O . HOH CA 10 . ? 7.482 45.740 -7.329 1.00 35.22 ? 1318 HOH B O 1 HETATM 9732 O O . HOH CA 10 . ? 53.216 63.208 -14.238 1.00 35.78 ? 1319 HOH B O 1 HETATM 9733 O O . HOH CA 10 . ? 8.084 30.547 -9.810 1.00 31.28 ? 1320 HOH B O 1 HETATM 9734 O O . HOH CA 10 . ? 65.687 26.504 0.541 1.00 34.27 ? 1321 HOH B O 1 HETATM 9735 O O . HOH CA 10 . ? 28.234 62.878 -16.291 1.00 38.60 ? 1322 HOH B O 1 HETATM 9736 O O . HOH CA 10 . ? 48.533 29.933 9.497 1.00 32.28 ? 1323 HOH B O 1 HETATM 9737 O O . HOH CA 10 . ? 46.455 49.986 -31.163 1.00 34.84 ? 1324 HOH B O 1 HETATM 9738 O O . HOH CA 10 . ? 71.442 52.885 -8.080 1.00 46.40 ? 1325 HOH B O 1 HETATM 9739 O O . HOH CA 10 . ? 40.311 52.902 10.505 1.00 45.83 ? 1326 HOH B O 1 HETATM 9740 O O . HOH CA 10 . ? 27.086 57.934 -23.162 1.00 31.27 ? 1327 HOH B O 1 HETATM 9741 O O . HOH CA 10 . ? 72.830 45.805 -1.663 1.00 37.73 ? 1328 HOH B O 1 HETATM 9742 O O . HOH CA 10 . ? 44.216 48.658 12.731 1.00 36.15 ? 1329 HOH B O 1 HETATM 9743 O O . HOH CA 10 . ? 64.956 30.423 1.649 1.00 38.25 ? 1330 HOH B O 1 HETATM 9744 O O . HOH CA 10 . ? 71.529 28.958 1.393 1.00 36.78 ? 1331 HOH B O 1 HETATM 9745 O O . HOH CA 10 . ? 76.331 38.181 -20.912 1.00 34.62 ? 1332 HOH B O 1 HETATM 9746 O O . HOH CA 10 . ? 52.552 48.319 -32.717 1.00 40.46 ? 1333 HOH B O 1 HETATM 9747 O O . HOH CA 10 . ? 13.106 36.084 -1.711 1.00 39.51 ? 1334 HOH B O 1 HETATM 9748 O O . HOH CA 10 . ? 14.313 48.855 -9.998 1.00 31.49 ? 1335 HOH B O 1 HETATM 9749 O O . HOH CA 10 . ? 65.963 21.593 -32.943 1.00 39.52 ? 1336 HOH B O 1 HETATM 9750 O O . HOH CA 10 . ? 55.102 34.694 8.722 1.00 38.41 ? 1337 HOH B O 1 HETATM 9751 O O . HOH CA 10 . ? 5.487 49.110 -11.939 1.00 38.67 ? 1338 HOH B O 1 HETATM 9752 O O . HOH CA 10 . ? 60.380 39.283 5.766 1.00 32.38 ? 1339 HOH B O 1 HETATM 9753 O O . HOH CA 10 . ? 10.959 55.740 2.929 1.00 39.89 ? 1340 HOH B O 1 HETATM 9754 O O . HOH CA 10 . ? 36.206 29.338 9.361 1.00 31.71 ? 1341 HOH B O 1 HETATM 9755 O O . HOH CA 10 . ? 68.528 56.376 -25.691 1.00 34.23 ? 1342 HOH B O 1 HETATM 9756 O O . HOH CA 10 . ? 18.473 46.120 8.658 1.00 19.43 ? 1343 HOH B O 1 HETATM 9757 O O . HOH CA 10 . ? 14.811 48.582 9.769 1.00 19.80 ? 1344 HOH B O 1 HETATM 9758 O O . HOH CA 10 . ? 65.744 45.679 -1.553 1.00 29.18 ? 1345 HOH B O 1 HETATM 9759 O O . HOH CA 10 . ? 13.365 56.359 3.704 1.00 25.18 ? 1346 HOH B O 1 HETATM 9760 O O . HOH CA 10 . ? 43.866 42.980 -31.225 1.00 30.87 ? 1347 HOH B O 1 HETATM 9761 O O . HOH CA 10 . ? 76.345 43.529 -23.783 1.00 30.30 ? 1348 HOH B O 1 HETATM 9762 O O . HOH CA 10 . ? 43.265 36.254 -33.868 1.00 38.36 ? 1349 HOH B O 1 HETATM 9763 O O . HOH CA 10 . ? 75.338 40.528 -17.621 1.00 32.28 ? 1350 HOH B O 1 HETATM 9764 O O . HOH CA 10 . ? 26.491 68.939 -8.978 1.00 41.36 ? 1351 HOH B O 1 HETATM 9765 O O . HOH CA 10 . ? 77.994 39.191 -22.735 1.00 35.49 ? 1352 HOH B O 1 HETATM 9766 O O . HOH CA 10 . ? 67.688 20.708 0.672 1.00 32.89 ? 1353 HOH B O 1 HETATM 9767 O O . HOH CA 10 . ? 10.487 46.471 -0.378 1.00 33.25 ? 1354 HOH B O 1 HETATM 9768 O O . HOH CA 10 . ? 67.602 26.449 -31.253 1.00 34.00 ? 1355 HOH B O 1 HETATM 9769 O O . HOH CA 10 . ? 42.423 29.848 -34.673 1.00 37.26 ? 1356 HOH B O 1 HETATM 9770 O O . HOH CA 10 . ? 55.425 36.392 -38.590 1.00 29.20 ? 1357 HOH B O 1 HETATM 9771 O O . HOH CA 10 . ? 55.432 29.879 -46.258 1.00 44.88 ? 1358 HOH B O 1 HETATM 9772 O O . HOH CA 10 . ? 72.483 24.460 -0.058 1.00 38.11 ? 1359 HOH B O 1 HETATM 9773 O O . HOH CA 10 . ? 19.464 57.170 6.132 1.00 33.34 ? 1360 HOH B O 1 HETATM 9774 O O . HOH CA 10 . ? 78.361 41.766 -1.928 1.00 32.59 ? 1361 HOH B O 1 HETATM 9775 O O . HOH CA 10 . ? 72.537 20.429 -31.023 1.00 40.71 ? 1362 HOH B O 1 HETATM 9776 O O . HOH CA 10 . ? 77.007 47.228 -21.093 1.00 43.11 ? 1363 HOH B O 1 HETATM 9777 O O . HOH CA 10 . ? 28.879 30.002 11.627 1.00 36.33 ? 1364 HOH B O 1 HETATM 9778 O O . HOH CA 10 . ? 67.124 24.574 -15.115 1.00 35.11 ? 1365 HOH B O 1 HETATM 9779 O O . HOH CA 10 . ? 38.022 21.886 -9.777 1.00 34.71 ? 1367 HOH B O 1 HETATM 9780 O O . HOH CA 10 . ? 21.270 62.045 -11.587 1.00 27.48 ? 1368 HOH B O 1 HETATM 9781 O O . HOH CA 10 . ? 33.342 47.243 -7.776 1.00 35.00 ? 1369 HOH B O 1 HETATM 9782 O O . HOH CA 10 . ? 30.964 29.809 9.981 1.00 40.07 ? 1370 HOH B O 1 HETATM 9783 O O . HOH CA 10 . ? 59.089 54.554 -23.256 1.00 32.53 ? 1371 HOH B O 1 HETATM 9784 O O . HOH CA 10 . ? 28.157 22.449 -11.659 1.00 28.91 ? 1372 HOH B O 1 HETATM 9785 O O . HOH CA 10 . ? 39.689 32.869 9.370 1.00 40.25 ? 1373 HOH B O 1 HETATM 9786 O O . HOH CA 10 . ? 45.184 42.668 -38.868 1.00 46.98 ? 1374 HOH B O 1 HETATM 9787 O O . HOH CA 10 . ? 60.405 18.217 -19.617 1.00 42.78 ? 1375 HOH B O 1 HETATM 9788 O O . HOH CA 10 . ? 53.794 17.623 -11.129 1.00 44.18 ? 1376 HOH B O 1 HETATM 9789 O O . HOH CA 10 . ? 67.784 42.372 1.359 1.00 40.33 ? 1377 HOH B O 1 HETATM 9790 O O . HOH CA 10 . ? 50.870 22.977 10.951 1.00 42.61 ? 1378 HOH B O 1 HETATM 9791 O O . HOH CA 10 . ? 46.425 64.449 -12.663 1.00 40.35 ? 1379 HOH B O 1 HETATM 9792 O O . HOH CA 10 . ? 37.886 33.374 12.311 1.00 39.97 ? 1380 HOH B O 1 HETATM 9793 O O . HOH CA 10 . ? 38.616 28.064 -7.387 1.00 22.17 ? 1381 HOH B O 1 HETATM 9794 O O . HOH CA 10 . ? 29.583 34.677 -30.835 1.00 43.96 ? 1382 HOH B O 1 HETATM 9795 O O . HOH CA 10 . ? 43.627 41.405 -25.316 1.00 25.67 ? 1383 HOH B O 1 HETATM 9796 O O . HOH CA 10 . ? 55.904 38.627 -40.372 1.00 29.52 ? 1384 HOH B O 1 HETATM 9797 O O . HOH CA 10 . ? 70.291 17.626 -31.272 1.00 34.04 ? 1385 HOH B O 1 HETATM 9798 O O . HOH CA 10 . ? 57.077 16.681 -19.731 1.00 32.23 ? 1386 HOH B O 1 HETATM 9799 O O . HOH CA 10 . ? 50.699 17.117 -36.846 1.00 27.74 ? 1387 HOH B O 1 HETATM 9800 O O . HOH CA 10 . ? 27.090 40.278 -25.192 1.00 36.49 ? 1388 HOH B O 1 HETATM 9801 O O . HOH CA 10 . ? 56.628 41.020 5.053 1.00 28.29 ? 1389 HOH B O 1 HETATM 9802 O O . HOH CA 10 . ? 33.147 56.987 3.704 1.00 25.02 ? 1390 HOH B O 1 HETATM 9803 O O . HOH CA 10 . ? 55.473 33.830 -39.113 1.00 27.60 ? 1391 HOH B O 1 HETATM 9804 O O . HOH CA 10 . ? 65.330 21.590 -0.023 1.00 29.11 ? 1392 HOH B O 1 HETATM 9805 O O . HOH CA 10 . ? 58.203 25.042 3.184 1.00 22.69 ? 1393 HOH B O 1 HETATM 9806 O O . HOH CA 10 . ? 41.232 28.580 -30.414 1.00 26.84 ? 1394 HOH B O 1 HETATM 9807 O O . HOH CA 10 . ? 39.199 22.806 -16.502 1.00 35.31 ? 1395 HOH B O 1 HETATM 9808 O O . HOH CA 10 . ? 27.149 30.893 -26.199 1.00 24.89 ? 1396 HOH B O 1 HETATM 9809 O O . HOH CA 10 . ? 56.602 24.587 -7.823 1.00 25.81 ? 1397 HOH B O 1 HETATM 9810 O O . HOH CA 10 . ? 34.969 55.959 -5.796 1.00 31.36 ? 1398 HOH B O 1 HETATM 9811 O O . HOH CA 10 . ? 33.497 28.112 -6.975 1.00 25.95 ? 1399 HOH B O 1 HETATM 9812 O O . HOH CA 10 . ? 38.049 54.461 10.657 1.00 30.81 ? 1400 HOH B O 1 HETATM 9813 O O . HOH CA 10 . ? 43.067 60.848 -21.717 1.00 24.43 ? 1401 HOH B O 1 HETATM 9814 O O . HOH CA 10 . ? 32.875 44.046 -30.918 1.00 37.16 ? 1402 HOH B O 1 HETATM 9815 O O . HOH CA 10 . ? 52.683 38.577 10.321 1.00 33.56 ? 1403 HOH B O 1 HETATM 9816 O O . HOH CA 10 . ? 23.413 55.244 7.678 1.00 34.32 ? 1404 HOH B O 1 HETATM 9817 O O . HOH CA 10 . ? 76.001 46.298 -23.685 1.00 29.05 ? 1405 HOH B O 1 HETATM 9818 O O . HOH CA 10 . ? 42.524 40.250 11.825 1.00 33.77 ? 1406 HOH B O 1 HETATM 9819 O O . HOH CA 10 . ? 67.487 17.614 0.370 1.00 42.57 ? 1407 HOH B O 1 HETATM 9820 O O . HOH CA 10 . ? 15.241 39.745 1.605 1.00 38.14 ? 1408 HOH B O 1 HETATM 9821 O O . HOH CA 10 . ? 68.240 27.845 -2.519 1.00 29.35 ? 1409 HOH B O 1 HETATM 9822 O O . HOH CA 10 . ? 48.892 19.018 -36.379 1.00 32.95 ? 1410 HOH B O 1 HETATM 9823 O O . HOH CA 10 . ? 55.704 21.840 -37.735 1.00 28.10 ? 1411 HOH B O 1 HETATM 9824 O O . HOH CA 10 . ? 63.767 18.514 -5.408 1.00 36.70 ? 1412 HOH B O 1 HETATM 9825 O O . HOH CA 10 . ? 28.683 42.143 -26.334 1.00 30.03 ? 1413 HOH B O 1 HETATM 9826 O O . HOH CA 10 . ? 58.990 21.563 -6.205 1.00 35.75 ? 1414 HOH B O 1 HETATM 9827 O O . HOH CA 10 . ? 52.628 22.369 5.367 1.00 35.90 ? 1415 HOH B O 1 HETATM 9828 O O . HOH CA 10 . ? 63.489 19.740 -0.613 1.00 37.05 ? 1416 HOH B O 1 HETATM 9829 O O . HOH CA 10 . ? 66.336 35.699 2.891 1.00 39.22 ? 1417 HOH B O 1 HETATM 9830 O O . HOH CA 10 . ? 72.218 21.646 -28.100 1.00 41.80 ? 1418 HOH B O 1 HETATM 9831 O O . HOH CA 10 . ? 20.765 62.071 -8.710 1.00 31.71 ? 1419 HOH B O 1 HETATM 9832 O O . HOH CA 10 . ? 68.588 18.846 -21.751 1.00 41.53 ? 1420 HOH B O 1 HETATM 9833 O O . HOH CA 10 . ? 57.757 35.613 -33.047 1.00 30.54 ? 1421 HOH B O 1 HETATM 9834 O O . HOH CA 10 . ? 25.506 47.234 -23.998 1.00 33.77 ? 1422 HOH B O 1 HETATM 9835 O O . HOH CA 10 . ? 67.523 23.933 -34.271 1.00 32.59 ? 1423 HOH B O 1 HETATM 9836 O O . HOH CA 10 . ? 38.868 40.887 13.429 1.00 33.87 ? 1424 HOH B O 1 HETATM 9837 O O . HOH CA 10 . ? 16.705 62.514 -7.242 1.00 31.73 ? 1425 HOH B O 1 HETATM 9838 O O . HOH CA 10 . ? 56.257 42.687 -36.712 1.00 31.30 ? 1426 HOH B O 1 HETATM 9839 O O . HOH CA 10 . ? 32.276 57.541 6.410 1.00 30.63 ? 1427 HOH B O 1 HETATM 9840 O O . HOH CA 10 . ? 45.839 19.168 -5.749 1.00 42.78 ? 1428 HOH B O 1 HETATM 9841 O O . HOH CA 10 . ? 29.134 36.366 -28.876 1.00 30.08 ? 1429 HOH B O 1 HETATM 9842 O O . HOH CA 10 . ? 58.046 52.191 -23.912 1.00 32.84 ? 1430 HOH B O 1 HETATM 9843 O O . HOH CA 10 . ? 59.568 15.692 -20.264 1.00 33.76 ? 1431 HOH B O 1 HETATM 9844 O O . HOH CA 10 . ? 30.858 18.604 -12.154 1.00 33.18 ? 1432 HOH B O 1 HETATM 9845 O O . HOH CA 10 . ? 61.965 46.129 2.715 1.00 30.97 ? 1433 HOH B O 1 HETATM 9846 O O . HOH CA 10 . ? 63.679 28.309 0.436 1.00 28.70 ? 1434 HOH B O 1 HETATM 9847 O O . HOH CA 10 . ? 61.836 21.592 -31.762 1.00 33.96 ? 1435 HOH B O 1 HETATM 9848 O O . HOH CA 10 . ? 77.885 34.140 -20.679 1.00 36.53 ? 1436 HOH B O 1 HETATM 9849 O O . HOH CA 10 . ? 79.450 37.472 -27.958 1.00 37.09 ? 1437 HOH B O 1 HETATM 9850 O O . HOH CA 10 . ? 62.183 16.862 -26.880 1.00 32.67 ? 1438 HOH B O 1 HETATM 9851 O O . HOH CA 10 . ? 49.805 56.570 -29.661 1.00 42.07 ? 1439 HOH B O 1 HETATM 9852 O O . HOH CA 10 . ? 51.932 58.138 6.710 1.00 34.10 ? 1440 HOH B O 1 HETATM 9853 O O . HOH CA 10 . ? 50.252 38.140 9.201 1.00 34.38 ? 1441 HOH B O 1 HETATM 9854 O O . HOH CA 10 . ? 13.319 40.244 -0.668 1.00 36.84 ? 1442 HOH B O 1 HETATM 9855 O O . HOH CA 10 . ? 51.276 59.129 0.194 1.00 38.00 ? 1443 HOH B O 1 HETATM 9856 O O . HOH CA 10 . ? 42.544 50.781 -27.883 1.00 47.57 ? 1444 HOH B O 1 HETATM 9857 O O . HOH CA 10 . ? 48.661 61.537 -15.713 1.00 43.53 ? 1445 HOH B O 1 HETATM 9858 O O . HOH CA 10 . ? 59.788 33.528 -35.131 1.00 45.24 ? 1446 HOH B O 1 HETATM 9859 O O . HOH CA 10 . ? 50.891 55.115 9.805 1.00 32.97 ? 1447 HOH B O 1 HETATM 9860 O O . HOH CA 10 . ? 37.793 22.759 -25.390 1.00 45.84 ? 1448 HOH B O 1 HETATM 9861 O O . HOH CA 10 . ? 54.514 36.901 9.809 1.00 34.41 ? 1449 HOH B O 1 HETATM 9862 O O . HOH CA 10 . ? 22.376 24.644 -13.383 1.00 37.22 ? 1450 HOH B O 1 HETATM 9863 O O . HOH CA 10 . ? 75.967 24.107 -12.457 1.00 30.00 ? 1451 HOH B O 1 HETATM 9864 O O . HOH CA 10 . ? 73.636 36.956 -2.763 1.00 31.30 ? 1452 HOH B O 1 HETATM 9865 O O . HOH CA 10 . ? 36.245 56.754 5.977 1.00 35.96 ? 1453 HOH B O 1 HETATM 9866 O O . HOH CA 10 . ? 31.521 27.548 -26.070 1.00 49.95 ? 1454 HOH B O 1 HETATM 9867 O O . HOH CA 10 . ? 47.677 53.589 -29.154 1.00 40.53 ? 1455 HOH B O 1 HETATM 9868 O O . HOH CA 10 . ? 39.339 22.004 -12.323 1.00 32.94 ? 1456 HOH B O 1 HETATM 9869 O O . HOH CA 10 . ? 26.739 49.041 -22.767 1.00 33.99 ? 1457 HOH B O 1 HETATM 9870 O O . HOH CA 10 . ? 30.617 46.838 -6.846 1.00 31.57 ? 1458 HOH B O 1 HETATM 9871 O O . HOH CA 10 . ? 76.592 41.780 -19.723 1.00 31.63 ? 1459 HOH B O 1 HETATM 9872 O O . HOH CA 10 . ? 28.472 46.560 -27.862 1.00 42.73 ? 1460 HOH B O 1 HETATM 9873 O O . HOH CA 10 . ? 45.683 20.983 0.408 1.00 33.98 ? 1461 HOH B O 1 HETATM 9874 O O . HOH CA 10 . ? 36.400 47.087 -31.422 1.00 39.42 ? 1462 HOH B O 1 HETATM 9875 O O . HOH CA 10 . ? 58.343 56.988 -18.090 1.00 32.76 ? 1464 HOH B O 1 HETATM 9876 O O . HOH CA 10 . ? 19.046 59.331 1.894 1.00 31.32 ? 1465 HOH B O 1 HETATM 9877 O O . HOH CA 10 . ? 36.181 36.307 11.858 1.00 44.74 ? 1466 HOH B O 1 HETATM 9878 O O . HOH CA 10 . ? 43.776 33.594 10.064 1.00 41.37 ? 1467 HOH B O 1 HETATM 9879 O O . HOH CA 10 . ? 66.334 40.115 0.615 1.00 36.26 ? 1468 HOH B O 1 HETATM 9880 O O . HOH CA 10 . ? 26.217 21.992 -13.685 1.00 28.47 ? 1469 HOH B O 1 HETATM 9881 O O . HOH CA 10 . ? 57.653 33.370 -37.432 1.00 34.97 ? 1470 HOH B O 1 HETATM 9882 O O . HOH CA 10 . ? 36.711 50.547 11.952 1.00 35.24 ? 1471 HOH B O 1 HETATM 9883 O O . HOH CA 10 . ? 46.837 46.689 -34.397 1.00 37.54 ? 1472 HOH B O 1 HETATM 9884 O O . HOH CA 10 . ? 68.907 51.695 -27.210 1.00 31.60 ? 1473 HOH B O 1 HETATM 9885 O O . HOH CA 10 . ? 63.282 56.466 -11.140 1.00 42.64 ? 1474 HOH B O 1 HETATM 9886 O O . HOH CA 10 . ? 52.771 54.127 -28.212 1.00 35.87 ? 1475 HOH B O 1 HETATM 9887 O O . HOH CA 10 . ? 42.893 19.710 -11.667 1.00 47.52 ? 1476 HOH B O 1 HETATM 9888 O O . HOH CA 10 . ? 45.598 60.962 -7.569 1.00 46.84 ? 1477 HOH B O 1 HETATM 9889 O O . HOH CA 10 . ? 18.096 33.826 2.255 1.00 37.31 ? 1478 HOH B O 1 HETATM 9890 O O . HOH CA 10 . ? 38.824 43.331 -30.652 1.00 33.18 ? 1479 HOH B O 1 HETATM 9891 O O . HOH CA 10 . ? 22.585 31.199 4.183 1.00 37.02 ? 1480 HOH B O 1 HETATM 9892 O O . HOH CA 10 . ? 43.694 44.964 -38.353 1.00 45.36 ? 1481 HOH B O 1 HETATM 9893 O O . HOH CA 10 . ? 36.904 55.453 -3.913 1.00 37.45 ? 1482 HOH B O 1 HETATM 9894 O O . HOH CA 10 . ? 62.105 47.427 -33.997 1.00 32.61 ? 1483 HOH B O 1 HETATM 9895 O O . HOH CA 10 . ? 41.445 34.416 -34.268 1.00 32.60 ? 1484 HOH B O 1 HETATM 9896 O O . HOH CA 10 . ? 22.728 33.532 -1.498 1.00 29.15 ? 1485 HOH B O 1 HETATM 9897 O O . HOH CA 10 . ? 50.242 60.614 4.454 1.00 33.15 ? 1486 HOH B O 1 HETATM 9898 O O . HOH CA 10 . ? 69.904 18.233 -26.946 1.00 31.92 ? 1487 HOH B O 1 HETATM 9899 O O . HOH CA 10 . ? 49.129 13.005 -4.216 1.00 40.84 ? 1488 HOH B O 1 HETATM 9900 O O . HOH CA 10 . ? 59.830 23.352 4.608 1.00 34.45 ? 1489 HOH B O 1 HETATM 9901 O O . HOH CA 10 . ? 56.491 16.711 -13.571 1.00 32.50 ? 1490 HOH B O 1 HETATM 9902 O O . HOH CA 10 . ? 45.283 21.415 -33.718 1.00 36.83 ? 1491 HOH B O 1 HETATM 9903 O O . HOH CA 10 . ? 13.391 51.749 -13.693 1.00 39.10 ? 1492 HOH B O 1 HETATM 9904 O O . HOH CA 10 . ? 27.318 64.820 -7.636 1.00 38.10 ? 1493 HOH B O 1 HETATM 9905 O O . HOH CA 10 . ? 16.023 28.386 -18.833 1.00 38.12 ? 1494 HOH B O 1 HETATM 9906 O O . HOH CA 10 . ? 51.090 17.832 -8.749 1.00 29.55 ? 1495 HOH B O 1 HETATM 9907 O O . HOH CA 10 . ? 44.255 63.099 -6.581 1.00 39.48 ? 1496 HOH B O 1 HETATM 9908 O O . HOH CA 10 . ? 15.164 31.638 -4.909 1.00 33.26 ? 1497 HOH B O 1 HETATM 9909 O O . HOH CA 10 . ? 77.568 25.991 -16.589 1.00 39.49 ? 1498 HOH B O 1 HETATM 9910 O O . HOH CA 10 . ? 66.410 30.529 -31.712 1.00 40.43 ? 1499 HOH B O 1 HETATM 9911 O O . HOH CA 10 . ? 56.929 27.439 -40.643 1.00 36.28 ? 1500 HOH B O 1 HETATM 9912 O O . HOH CA 10 . ? 38.067 49.746 -28.128 1.00 36.49 ? 1501 HOH B O 1 HETATM 9913 O O . HOH CA 10 . ? 17.353 65.990 -16.352 1.00 39.09 ? 1502 HOH B O 1 HETATM 9914 O O . HOH CA 10 . ? 58.098 45.507 4.545 1.00 38.19 ? 1503 HOH B O 1 HETATM 9915 O O . HOH CA 10 . ? 39.948 16.799 -0.370 1.00 41.88 ? 1505 HOH B O 1 HETATM 9916 O O . HOH CA 10 . ? 48.524 44.567 12.286 1.00 36.53 ? 1506 HOH B O 1 HETATM 9917 O O . HOH CA 10 . ? 58.050 30.386 -44.572 1.00 38.02 ? 1507 HOH B O 1 HETATM 9918 O O . HOH CA 10 . ? 43.349 24.755 3.187 1.00 31.69 ? 1508 HOH B O 1 HETATM 9919 O O . HOH CA 10 . ? 46.054 59.821 -25.997 1.00 37.67 ? 1509 HOH B O 1 HETATM 9920 O O . HOH CA 10 . ? 13.664 51.536 -9.812 1.00 40.67 ? 1510 HOH B O 1 HETATM 9921 O O . HOH CA 10 . ? 49.769 21.631 6.665 1.00 39.84 ? 1511 HOH B O 1 HETATM 9922 O O . HOH CA 10 . ? 45.492 24.209 -33.836 1.00 32.32 ? 1512 HOH B O 1 HETATM 9923 O O . HOH CA 10 . ? 58.765 41.745 -37.915 1.00 44.21 ? 1513 HOH B O 1 HETATM 9924 O O . HOH CA 10 . ? 51.521 17.420 -39.451 1.00 39.84 ? 1514 HOH B O 1 HETATM 9925 O O . HOH CA 10 . ? 18.492 32.946 -1.070 1.00 46.16 ? 1515 HOH B O 1 HETATM 9926 O O . HOH CA 10 . ? 45.035 38.900 -37.892 1.00 43.13 ? 1516 HOH B O 1 HETATM 9927 O O . HOH CA 10 . ? 44.977 28.078 -31.453 1.00 33.01 ? 1517 HOH B O 1 HETATM 9928 O O . HOH CA 10 . ? 30.255 41.941 -30.783 1.00 41.38 ? 1518 HOH B O 1 HETATM 9929 O O . HOH CA 10 . ? 23.676 43.253 -25.381 1.00 40.63 ? 1519 HOH B O 1 HETATM 9930 O O . HOH CA 10 . ? 38.825 25.017 -28.758 1.00 43.67 ? 1520 HOH B O 1 HETATM 9931 O O . HOH CA 10 . ? 65.830 41.744 -33.394 1.00 44.12 ? 1521 HOH B O 1 HETATM 9932 O O . HOH CA 10 . ? 67.434 18.961 -33.905 1.00 42.37 ? 1522 HOH B O 1 HETATM 9933 O O . HOH CA 10 . ? 60.139 21.646 -1.811 1.00 41.47 ? 1523 HOH B O 1 HETATM 9934 O O . HOH CA 10 . ? 47.235 14.662 -3.451 1.00 34.94 ? 1524 HOH B O 1 HETATM 9935 O O . HOH CA 10 . ? 30.724 27.493 1.825 1.00 40.18 ? 1525 HOH B O 1 HETATM 9936 O O . HOH CA 10 . ? 32.164 63.652 -1.227 1.00 41.02 ? 1526 HOH B O 1 HETATM 9937 O O . HOH CA 10 . ? 61.584 31.679 -39.415 1.00 44.54 ? 1527 HOH B O 1 HETATM 9938 O O . HOH CA 10 . ? 55.161 50.720 7.516 1.00 38.47 ? 1528 HOH B O 1 HETATM 9939 O O . HOH CA 10 . ? 58.714 20.924 -34.292 1.00 32.22 ? 1529 HOH B O 1 HETATM 9940 O O . HOH CA 10 . ? 40.389 22.670 -18.755 1.00 38.29 ? 1530 HOH B O 1 HETATM 9941 O O . HOH CA 10 . ? 11.347 48.544 -15.947 1.00 35.91 ? 1531 HOH B O 1 HETATM 9942 O O . HOH CA 10 . ? 33.666 39.318 -6.420 1.00 38.54 ? 1532 HOH B O 1 HETATM 9943 O O . HOH CA 10 . ? 19.527 53.849 -20.263 1.00 37.75 ? 1533 HOH B O 1 HETATM 9944 O O . HOH CA 10 . ? 39.962 16.705 -20.063 1.00 39.91 ? 1534 HOH B O 1 HETATM 9945 O O . HOH CA 10 . ? 57.014 43.809 -34.241 1.00 37.32 ? 1536 HOH B O 1 HETATM 9946 O O . HOH CA 10 . ? 70.861 27.871 -31.432 1.00 46.01 ? 1537 HOH B O 1 HETATM 9947 O O . HOH CA 10 . ? 46.416 62.104 -19.146 1.00 32.14 ? 1538 HOH B O 1 HETATM 9948 O O . HOH CA 10 . ? 21.549 65.700 -5.493 1.00 46.28 ? 1539 HOH B O 1 HETATM 9949 O O . HOH CA 10 . ? 14.381 63.141 -6.050 1.00 37.85 ? 1540 HOH B O 1 HETATM 9950 O O . HOH CA 10 . ? 59.537 55.294 1.381 1.00 43.20 ? 1541 HOH B O 1 HETATM 9951 O O . HOH CA 10 . ? 63.197 28.615 -38.021 1.00 41.29 ? 1542 HOH B O 1 HETATM 9952 O O . HOH CA 10 . ? 40.217 48.442 -27.485 1.00 29.34 ? 1543 HOH B O 1 HETATM 9953 O O . HOH CA 10 . ? 62.899 17.487 -20.249 1.00 48.01 ? 1544 HOH B O 1 HETATM 9954 O O . HOH CA 10 . ? 63.974 34.131 -36.441 1.00 39.05 ? 1545 HOH B O 1 HETATM 9955 O O . HOH CA 10 . ? 41.009 45.446 -32.622 1.00 36.98 ? 1546 HOH B O 1 HETATM 9956 O O . HOH CA 10 . ? 56.355 37.173 7.929 1.00 47.73 ? 1547 HOH B O 1 HETATM 9957 O O . HOH CA 10 . ? 34.870 27.402 -9.040 1.00 47.91 ? 1548 HOH B O 1 HETATM 9958 O O . HOH CA 10 . ? 12.187 57.755 -1.047 1.00 38.71 ? 1549 HOH B O 1 HETATM 9959 O O . HOH CA 10 . ? 32.833 21.364 -5.979 1.00 42.39 ? 1550 HOH B O 1 HETATM 9960 O O . HOH CA 10 . ? 50.487 60.394 -4.501 1.00 47.35 ? 1551 HOH B O 1 HETATM 9961 O O . HOH CA 10 . ? 43.403 43.007 12.592 1.00 39.35 ? 1552 HOH B O 1 HETATM 9962 O O . HOH CA 10 . ? 17.947 50.911 -19.779 1.00 43.05 ? 1553 HOH B O 1 HETATM 9963 O O . HOH CA 10 . ? 25.390 51.478 -24.125 1.00 47.79 ? 1554 HOH B O 1 HETATM 9964 O O . HOH CA 10 . ? 37.896 57.997 -3.758 1.00 39.07 ? 1555 HOH B O 1 HETATM 9965 O O . HOH CA 10 . ? 28.256 24.693 -10.199 1.00 34.77 ? 1556 HOH B O 1 HETATM 9966 O O . HOH CA 10 . ? 47.149 36.522 10.456 1.00 41.23 ? 1557 HOH B O 1 HETATM 9967 O O . HOH CA 10 . ? 27.026 24.959 -7.021 1.00 41.97 ? 1558 HOH B O 1 HETATM 9968 O O . HOH CA 10 . ? 69.757 20.920 -26.921 1.00 41.47 ? 1559 HOH B O 1 HETATM 9969 O O . HOH CA 10 . ? 69.710 28.484 -29.018 1.00 42.45 ? 1560 HOH B O 1 HETATM 9970 O O . HOH CA 10 . ? 40.995 58.036 -0.185 1.00 43.64 ? 1561 HOH B O 1 HETATM 9971 O O . HOH CA 10 . ? 50.399 57.607 9.057 1.00 42.83 ? 1562 HOH B O 1 HETATM 9972 O O . HOH CA 10 . ? 13.530 62.095 -3.592 1.00 36.05 ? 1563 HOH B O 1 HETATM 9973 O O . HOH CA 10 . ? 18.136 64.747 -6.022 1.00 46.69 ? 1564 HOH B O 1 HETATM 9974 O O . HOH CA 10 . ? 33.451 63.621 -11.165 1.00 40.89 ? 1565 HOH B O 1 HETATM 9975 O O . HOH CA 10 . ? 33.692 53.481 13.448 1.00 49.28 ? 1566 HOH B O 1 HETATM 9976 O O . HOH CA 10 . ? 58.454 26.422 8.076 1.00 44.13 ? 1567 HOH B O 1 HETATM 9977 O O . HOH CA 10 . ? 60.162 37.886 -33.086 1.00 37.68 ? 1569 HOH B O 1 HETATM 9978 O O . HOH CA 10 . ? 14.400 29.431 -7.805 1.00 44.72 ? 1570 HOH B O 1 HETATM 9979 O O . HOH CA 10 . ? 38.682 62.098 -19.396 1.00 42.31 ? 1571 HOH B O 1 HETATM 9980 O O . HOH CA 10 . ? 46.721 17.952 -2.774 1.00 36.25 ? 1573 HOH B O 1 HETATM 9981 O O . HOH CA 10 . ? 63.367 42.984 3.648 1.00 44.87 ? 1574 HOH B O 1 HETATM 9982 O O . HOH CA 10 . ? 44.366 22.800 1.738 1.00 45.75 ? 1575 HOH B O 1 HETATM 9983 O O . HOH CA 10 . ? 45.559 28.199 11.795 1.00 40.79 ? 1576 HOH B O 1 HETATM 9984 O O . HOH CA 10 . ? 67.923 30.075 3.439 1.00 45.41 ? 1577 HOH B O 1 HETATM 9985 O O . HOH CA 10 . ? 54.450 45.233 8.733 1.00 39.38 ? 1578 HOH B O 1 HETATM 9986 O O . HOH CA 10 . ? 39.920 20.755 1.003 1.00 38.75 ? 1579 HOH B O 1 HETATM 9987 O O . HOH CA 10 . ? 73.142 31.579 -3.624 1.00 44.59 ? 1580 HOH B O 1 HETATM 9988 O O . HOH CA 10 . ? 61.837 43.683 -35.448 1.00 43.38 ? 1581 HOH B O 1 HETATM 9989 O O . HOH CA 10 . ? 62.147 31.945 -36.346 1.00 49.65 ? 1582 HOH B O 1 HETATM 9990 O O . HOH CA 10 . ? 64.442 39.390 -33.219 1.00 33.66 ? 1583 HOH B O 1 HETATM 9991 O O . HOH CA 10 . ? 24.294 63.598 1.531 1.00 43.85 ? 1585 HOH B O 1 HETATM 9992 O O . HOH CA 10 . ? 71.585 50.871 -26.098 1.00 33.71 ? 1586 HOH B O 1 HETATM 9993 O O . HOH CA 10 . ? 71.460 47.196 -9.640 1.00 38.62 ? 1587 HOH B O 1 HETATM 9994 O O . HOH CA 10 . ? 56.063 23.634 8.012 1.00 45.74 ? 1588 HOH B O 1 HETATM 9995 O O . HOH CA 10 . ? 66.506 20.702 -16.038 1.00 47.79 ? 1589 HOH B O 1 HETATM 9996 O O . HOH CA 10 . ? 75.438 34.344 -21.770 1.00 40.94 ? 1590 HOH B O 1 HETATM 9997 O O . HOH CA 10 . ? 11.409 28.770 -14.056 1.00 44.49 ? 1591 HOH B O 1 HETATM 9998 O O . HOH CA 10 . ? 46.086 18.162 -12.989 1.00 33.63 ? 1592 HOH B O 1 HETATM 9999 O O . HOH CA 10 . ? 43.544 29.562 -30.071 1.00 34.06 ? 1593 HOH B O 1 HETATM 10000 O O . HOH CA 10 . ? 21.179 30.055 -4.342 1.00 30.65 ? 1594 HOH B O 1 HETATM 10001 O O . HOH CA 10 . ? 21.713 59.369 -0.140 1.00 38.30 ? 1595 HOH B O 1 HETATM 10002 O O . HOH CA 10 . ? 48.139 33.842 8.957 1.00 27.37 ? 1596 HOH B O 1 HETATM 10003 O O . HOH CA 10 . ? 15.680 62.228 -15.495 1.00 47.23 ? 1597 HOH B O 1 HETATM 10004 O O . HOH CA 10 . ? 28.154 44.498 -26.401 1.00 40.42 ? 1598 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 LEU 1 1 1 LEU LEU A . n A 1 2 ALA 2 2 2 ALA ALA A . n A 1 3 THR 3 3 3 THR THR A . n A 1 4 THR 4 4 4 THR THR A . n A 1 5 SER 5 5 5 SER SER A . n A 1 6 ASP 6 6 6 ASP ASP A . n A 1 7 HIS 7 7 7 HIS HIS A . n A 1 8 ASP 8 8 8 ASP ASP A . n A 1 9 PHE 9 9 9 PHE PHE A . n A 1 10 SER 10 10 10 SER SER A . n A 1 11 TYR 11 11 11 TYR TYR A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 SER 13 13 13 SER SER A . n A 1 14 PHE 14 14 14 PHE PHE A . n A 1 15 ALA 15 15 15 ALA ALA A . n A 1 16 TYR 16 16 16 TYR TYR A . n A 1 17 ASP 17 17 17 ASP ASP A . n A 1 18 ALA 18 18 18 ALA ALA A . n A 1 19 THR 19 19 19 THR THR A . n A 1 20 ASP 20 20 20 ASP ASP A . n A 1 21 LEU 21 21 21 LEU LEU A . n A 1 22 GLU 22 22 22 GLU GLU A . n A 1 23 LEU 23 23 23 LEU LEU A . n A 1 24 GLU 24 24 24 GLU GLU A . n A 1 25 GLY 25 25 25 GLY GLY A . n A 1 26 SER 26 26 26 SER SER A . n A 1 27 TYR 27 27 27 TYR TYR A . n A 1 28 ASP 28 28 28 ASP ASP A . n A 1 29 TYR 29 29 29 TYR TYR A . n A 1 30 VAL 30 30 30 VAL VAL A . n A 1 31 ILE 31 31 31 ILE ILE A . n A 1 32 VAL 32 32 32 VAL VAL A . n A 1 33 GLY 33 33 33 GLY GLY A . n A 1 34 GLY 34 34 34 GLY GLY A . n A 1 35 GLY 35 35 35 GLY GLY A . n A 1 36 THR 36 36 36 THR THR A . n A 1 37 SER 37 37 37 SER SER A . n A 1 38 GLY 38 38 38 GLY GLY A . n A 1 39 CYS 39 39 39 CYS CYS A . n A 1 40 PRO 40 40 40 PRO PRO A . n A 1 41 LEU 41 41 41 LEU LEU A . n A 1 42 ALA 42 42 42 ALA ALA A . n A 1 43 ALA 43 43 43 ALA ALA A . n A 1 44 THR 44 44 44 THR THR A . n A 1 45 LEU 45 45 45 LEU LEU A . n A 1 46 SER 46 46 46 SER SER A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 LYS 50 50 50 LYS LYS A . n A 1 51 VAL 51 51 51 VAL VAL A . n A 1 52 LEU 52 52 52 LEU LEU A . n A 1 53 VAL 53 53 53 VAL VAL A . n A 1 54 LEU 54 54 54 LEU LEU A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 ARG 56 56 56 ARG ARG A . n A 1 57 GLY 57 57 57 GLY GLY A . n A 1 58 SER 58 58 58 SER SER A . n A 1 59 LEU 59 59 59 LEU LEU A . n A 1 60 PRO 60 60 60 PRO PRO A . n A 1 61 THR 61 61 61 THR THR A . n A 1 62 ALA 62 62 62 ALA ALA A . n A 1 63 TYR 63 63 63 TYR TYR A . n A 1 64 PRO 64 64 64 PRO PRO A . n A 1 65 ASN 65 65 65 ASN ASN A . n A 1 66 VAL 66 66 66 VAL VAL A . n A 1 67 LEU 67 67 67 LEU LEU A . n A 1 68 THR 68 68 68 THR THR A . n A 1 69 ALA 69 69 69 ALA ALA A . n A 1 70 ASP 70 70 70 ASP ASP A . n A 1 71 GLY 71 71 71 GLY GLY A . n A 1 72 PHE 72 72 72 PHE PHE A . n A 1 73 VAL 73 73 73 VAL VAL A . n A 1 74 TYR 74 74 74 TYR TYR A . n A 1 75 ASN 75 75 75 ASN ASN A . n A 1 76 LEU 76 76 76 LEU LEU A . n A 1 77 GLN 77 77 77 GLN GLN A . n A 1 78 GLN 78 78 78 GLN GLN A . n A 1 79 GLU 79 79 79 GLU GLU A . n A 1 80 ASP 80 80 80 ASP ASP A . n A 1 81 ASP 81 81 81 ASP ASP A . n A 1 82 GLY 82 82 82 GLY GLY A . n A 1 83 LYS 83 83 83 LYS LYS A . n A 1 84 THR 84 84 84 THR THR A . n A 1 85 PRO 85 85 85 PRO PRO A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 GLU 87 87 87 GLU GLU A . n A 1 88 ARG 88 88 88 ARG ARG A . n A 1 89 PHE 89 89 89 PHE PHE A . n A 1 90 VAL 90 90 90 VAL VAL A . n A 1 91 SER 91 91 91 SER SER A . n A 1 92 GLU 92 92 92 GLU GLU A . n A 1 93 ASP 93 93 93 ASP ASP A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 ILE 95 95 95 ILE ILE A . n A 1 96 ASP 96 96 96 ASP ASP A . n A 1 97 ASN 97 97 97 ASN ASN A . n A 1 98 VAL 98 98 98 VAL VAL A . n A 1 99 ARG 99 99 99 ARG ARG A . n A 1 100 GLY 100 100 100 GLY GLY A . n A 1 101 ARG 101 101 101 ARG ARG A . n A 1 102 VAL 102 102 102 VAL VAL A . n A 1 103 LEU 103 103 103 LEU LEU A . n A 1 104 GLY 104 104 104 GLY GLY A . n A 1 105 GLY 105 105 105 GLY GLY A . n A 1 106 THR 106 106 106 THR THR A . n A 1 107 SER 107 107 107 SER SER A . n A 1 108 ILE 108 108 108 ILE ILE A . n A 1 109 ILE 109 109 109 ILE ILE A . n A 1 110 ASN 110 110 110 ASN ASN A . n A 1 111 ALA 111 111 111 ALA ALA A . n A 1 112 GLY 112 112 112 GLY GLY A . n A 1 113 VAL 113 113 113 VAL VAL A . n A 1 114 TYR 114 114 114 TYR TYR A . n A 1 115 ALA 115 115 115 ALA ALA A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 ALA 117 117 117 ALA ALA A . n A 1 118 ASN 118 118 118 ASN ASN A . n A 1 119 THR 119 119 119 THR THR A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 ILE 121 121 121 ILE ILE A . n A 1 122 TYR 122 122 122 TYR TYR A . n A 1 123 SER 123 123 123 SER SER A . n A 1 124 ALA 124 124 124 ALA ALA A . n A 1 125 SER 125 125 125 SER SER A . n A 1 126 GLY 126 126 126 GLY GLY A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 ASP 128 128 128 ASP ASP A . n A 1 129 TRP 129 129 129 TRP TRP A . n A 1 130 ASP 130 130 130 ASP ASP A . n A 1 131 MET 131 131 131 MET MET A . n A 1 132 ASP 132 132 132 ASP ASP A . n A 1 133 LEU 133 133 133 LEU LEU A . n A 1 134 VAL 134 134 134 VAL VAL A . n A 1 135 ASN 135 135 135 ASN ASN A . n A 1 136 GLN 136 136 136 GLN GLN A . n A 1 137 THR 137 137 137 THR THR A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 GLU 139 139 139 GLU GLU A . n A 1 140 TRP 140 140 140 TRP TRP A . n A 1 141 VAL 141 141 141 VAL VAL A . n A 1 142 GLU 142 142 142 GLU GLU A . n A 1 143 ASP 143 143 143 ASP ASP A . n A 1 144 THR 144 144 144 THR THR A . n A 1 145 ILE 145 145 145 ILE ILE A . n A 1 146 VAL 146 146 146 VAL VAL A . n A 1 147 TYR 147 147 147 TYR TYR A . n A 1 148 LYS 148 148 148 LYS LYS A . n A 1 149 PRO 149 149 149 PRO PRO A . n A 1 150 ASN 150 150 150 ASN ASN A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 GLN 152 152 152 GLN GLN A . n A 1 153 SER 153 153 153 SER SER A . n A 1 154 TRP 154 154 154 TRP TRP A . n A 1 155 GLN 155 155 155 GLN GLN A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 VAL 157 157 157 VAL VAL A . n A 1 158 THR 158 158 158 THR THR A . n A 1 159 LYS 159 159 159 LYS LYS A . n A 1 160 THR 160 160 160 THR THR A . n A 1 161 ALA 161 161 161 ALA ALA A . n A 1 162 PHE 162 162 162 PHE PHE A . n A 1 163 LEU 163 163 163 LEU LEU A . n A 1 164 GLU 164 164 164 GLU GLU A . n A 1 165 ALA 165 165 165 ALA ALA A . n A 1 166 GLY 166 166 166 GLY GLY A . n A 1 167 VAL 167 167 167 VAL VAL A . n A 1 168 HIS 168 168 168 HIS HIS A . n A 1 169 PRO 169 169 169 PRO PRO A . n A 1 170 ASN 170 170 170 ASN ASN A . n A 1 171 HIS 171 171 171 HIS HIS A . n A 1 172 GLY 172 172 172 GLY GLY A . n A 1 173 PHE 173 173 173 PHE PHE A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 ASP 176 176 176 ASP ASP A . n A 1 177 HIS 177 177 177 HIS HIS A . n A 1 178 GLU 178 178 178 GLU GLU A . n A 1 179 GLU 179 179 179 GLU GLU A . n A 1 180 GLY 180 180 180 GLY GLY A . n A 1 181 THR 181 181 181 THR THR A . n A 1 182 ARG 182 182 182 ARG ARG A . n A 1 183 ILE 183 183 183 ILE ILE A . n A 1 184 THR 184 184 184 THR THR A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 SER 186 186 186 SER SER A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 PHE 188 188 188 PHE PHE A . n A 1 189 ASP 189 189 189 ASP ASP A . n A 1 190 ASN 190 190 190 ASN ASN A . n A 1 191 LYS 191 191 191 LYS LYS A . n A 1 192 GLY 192 192 192 GLY GLY A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 ARG 194 194 194 ARG ARG A . n A 1 195 HIS 195 195 195 HIS HIS A . n A 1 196 ALA 196 196 196 ALA ALA A . n A 1 197 ALA 197 197 197 ALA ALA A . n A 1 198 ASP 198 198 198 ASP ASP A . n A 1 199 GLU 199 199 199 GLU GLU A . n A 1 200 LEU 200 200 200 LEU LEU A . n A 1 201 LEU 201 201 201 LEU LEU A . n A 1 202 ASN 202 202 202 ASN ASN A . n A 1 203 LYS 203 203 203 LYS LYS A . n A 1 204 GLY 204 204 204 GLY GLY A . n A 1 205 ASN 205 205 205 ASN ASN A . n A 1 206 SER 206 206 206 SER SER A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 ASN 208 208 208 ASN ASN A . n A 1 209 LEU 209 209 209 LEU LEU A . n A 1 210 ARG 210 210 210 ARG ARG A . n A 1 211 VAL 211 211 211 VAL VAL A . n A 1 212 GLY 212 212 212 GLY GLY A . n A 1 213 VAL 213 213 213 VAL VAL A . n A 1 214 HIS 214 214 214 HIS HIS A . n A 1 215 ALA 215 215 215 ALA ALA A . n A 1 216 SER 216 216 216 SER SER A . n A 1 217 VAL 217 217 217 VAL VAL A . n A 1 218 GLU 218 218 218 GLU GLU A . n A 1 219 LYS 219 219 219 LYS LYS A . n A 1 220 ILE 220 220 220 ILE ILE A . n A 1 221 ILE 221 221 221 ILE ILE A . n A 1 222 PHE 222 222 222 PHE PHE A . n A 1 223 SER 223 223 223 SER SER A . n A 1 224 ASN 224 224 224 ASN ASN A . n A 1 225 ALA 225 225 225 ALA ALA A . n A 1 226 PRO 226 226 226 PRO PRO A . n A 1 227 GLY 227 227 227 GLY GLY A . n A 1 228 LEU 228 228 228 LEU LEU A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 ALA 230 230 230 ALA ALA A . n A 1 231 THR 231 231 231 THR THR A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 ILE 234 234 234 ILE ILE A . n A 1 235 TYR 235 235 235 TYR TYR A . n A 1 236 ARG 236 236 236 ARG ARG A . n A 1 237 ASP 237 237 237 ASP ASP A . n A 1 238 SER 238 238 238 SER SER A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 GLY 240 240 240 GLY GLY A . n A 1 241 THR 241 241 241 THR THR A . n A 1 242 PRO 242 242 242 PRO PRO A . n A 1 243 HIS 243 243 243 HIS HIS A . n A 1 244 GLN 244 244 244 GLN GLN A . n A 1 245 ALA 245 245 245 ALA ALA A . n A 1 246 PHE 246 246 246 PHE PHE A . n A 1 247 VAL 247 247 247 VAL VAL A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 SER 249 249 249 SER SER A . n A 1 250 LYS 250 250 250 LYS LYS A . n A 1 251 GLY 251 251 251 GLY GLY A . n A 1 252 GLU 252 252 252 GLU GLU A . n A 1 253 VAL 253 253 253 VAL VAL A . n A 1 254 ILE 254 254 254 ILE ILE A . n A 1 255 VAL 255 255 255 VAL VAL A . n A 1 256 SER 256 256 256 SER SER A . n A 1 257 ALA 257 257 257 ALA ALA A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 THR 259 259 259 THR THR A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 GLY 261 261 261 GLY GLY A . n A 1 262 THR 262 262 262 THR THR A . n A 1 263 PRO 263 263 263 PRO PRO A . n A 1 264 GLN 264 264 264 GLN GLN A . n A 1 265 LEU 265 265 265 LEU LEU A . n A 1 266 LEU 266 266 266 LEU LEU A . n A 1 267 LEU 267 267 267 LEU LEU A . n A 1 268 LEU 268 268 268 LEU LEU A . n A 1 269 SER 269 269 269 SER SER A . n A 1 270 GLY 270 270 270 GLY GLY A . n A 1 271 VAL 271 271 271 VAL VAL A . n A 1 272 GLY 272 272 272 GLY GLY A . n A 1 273 PRO 273 273 273 PRO PRO A . n A 1 274 GLU 274 274 274 GLU GLU A . n A 1 275 SER 275 275 275 SER SER A . n A 1 276 TYR 276 276 276 TYR TYR A . n A 1 277 LEU 277 277 277 LEU LEU A . n A 1 278 SER 278 278 278 SER SER A . n A 1 279 SER 279 279 279 SER SER A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 ASN 281 281 281 ASN ASN A . n A 1 282 ILE 282 282 282 ILE ILE A . n A 1 283 PRO 283 283 283 PRO PRO A . n A 1 284 VAL 284 284 284 VAL VAL A . n A 1 285 VAL 285 285 285 VAL VAL A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 SER 287 287 287 SER SER A . n A 1 288 HIS 288 288 288 HIS HIS A . n A 1 289 PRO 289 289 289 PRO PRO A . n A 1 290 TYR 290 290 290 TYR TYR A . n A 1 291 VAL 291 291 291 VAL VAL A . n A 1 292 GLY 292 292 292 GLY GLY A . n A 1 293 GLN 293 293 293 GLN GLN A . n A 1 294 PHE 294 294 294 PHE PHE A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 HIS 296 296 296 HIS HIS A . n A 1 297 ASP 297 297 297 ASP ASP A . n A 1 298 ASN 298 298 298 ASN ASN A . n A 1 299 PRO 299 299 299 PRO PRO A . n A 1 300 ARG 300 300 300 ARG ARG A . n A 1 301 ASN 301 301 301 ASN ASN A . n A 1 302 PHE 302 302 302 PHE PHE A . n A 1 303 ILE 303 303 303 ILE ILE A . n A 1 304 ASN 304 304 304 ASN ASN A . n A 1 305 ILE 305 305 305 ILE ILE A . n A 1 306 LEU 306 306 306 LEU LEU A . n A 1 307 PRO 307 307 307 PRO PRO A . n A 1 308 PRO 308 308 308 PRO PRO A . n A 1 309 ASN 309 309 309 ASN ASN A . n A 1 310 PRO 310 310 310 PRO PRO A . n A 1 311 ILE 311 311 311 ILE ILE A . n A 1 312 GLU 312 312 312 GLU GLU A . n A 1 313 PRO 313 313 313 PRO PRO A . n A 1 314 THR 314 314 314 THR THR A . n A 1 315 ILE 315 315 315 ILE ILE A . n A 1 316 VAL 316 316 316 VAL VAL A . n A 1 317 THR 317 317 317 THR THR A . n A 1 318 VAL 318 318 318 VAL VAL A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 GLY 320 320 320 GLY GLY A . n A 1 321 ILE 321 321 321 ILE ILE A . n A 1 322 SER 322 322 322 SER SER A . n A 1 323 ASN 323 323 323 ASN ASN A . n A 1 324 ASP 324 324 324 ASP ASP A . n A 1 325 PHE 325 325 325 PHE PHE A . n A 1 326 TYR 326 326 326 TYR TYR A . n A 1 327 GLN 327 327 327 GLN GLN A . n A 1 328 CYS 328 328 328 CYS CYS A . n A 1 329 SER 329 329 329 SER SER A . n A 1 330 PHE 330 330 330 PHE PHE A . n A 1 331 SER 331 331 331 SER SER A . n A 1 332 SER 332 332 332 SER SER A . n A 1 333 LEU 333 333 333 LEU LEU A . n A 1 334 PRO 334 334 334 PRO PRO A . n A 1 335 PHE 335 335 335 PHE PHE A . n A 1 336 THR 336 336 336 THR THR A . n A 1 337 THR 337 337 337 THR THR A . n A 1 338 PRO 338 338 338 PRO PRO A . n A 1 339 PRO 339 339 339 PRO PRO A . n A 1 340 PHE 340 340 340 PHE PHE A . n A 1 341 GLY 341 341 341 GLY GLY A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 PHE 343 343 343 PHE PHE A . n A 1 344 PRO 344 344 344 PRO PRO A . n A 1 345 SER 345 345 345 SER SER A . n A 1 346 SER 346 346 346 SER SER A . n A 1 347 SER 347 347 347 SER SER A . n A 1 348 TYR 348 348 348 TYR TYR A . n A 1 349 PRO 349 349 349 PRO PRO A . n A 1 350 LEU 350 350 350 LEU LEU A . n A 1 351 PRO 351 351 351 PRO PRO A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 SER 353 353 353 SER SER A . n A 1 354 THR 354 354 354 THR THR A . n A 1 355 PHE 355 355 355 PHE PHE A . n A 1 356 ALA 356 356 356 ALA ALA A . n A 1 357 HIS 357 357 357 HIS HIS A . n A 1 358 PHE 358 358 358 PHE PHE A . n A 1 359 ALA 359 359 359 ALA ALA A . n A 1 360 SER 360 360 360 SER SER A . n A 1 361 LYS 361 361 361 LYS LYS A . n A 1 362 VAL 362 362 362 VAL VAL A . n A 1 363 ALA 363 363 363 ALA ALA A . n A 1 364 GLY 364 364 364 GLY GLY A . n A 1 365 PRO 365 365 365 PRO PRO A . n A 1 366 LEU 366 366 366 LEU LEU A . n A 1 367 SER 367 367 367 SER SER A . n A 1 368 TYR 368 368 368 TYR TYR A . n A 1 369 GLY 369 369 369 GLY GLY A . n A 1 370 SER 370 370 370 SER SER A . n A 1 371 LEU 371 371 371 LEU LEU A . n A 1 372 THR 372 372 372 THR THR A . n A 1 373 LEU 373 373 373 LEU LEU A . n A 1 374 LYS 374 374 374 LYS LYS A . n A 1 375 SER 375 375 375 SER SER A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 SER 377 377 377 SER SER A . n A 1 378 ASN 378 378 378 ASN ASN A . n A 1 379 VAL 379 379 379 VAL VAL A . n A 1 380 ARG 380 380 380 ARG ARG A . n A 1 381 VAL 381 381 381 VAL VAL A . n A 1 382 SER 382 382 382 SER SER A . n A 1 383 PRO 383 383 383 PRO PRO A . n A 1 384 ASN 384 384 384 ASN ASN A . n A 1 385 VAL 385 385 385 VAL VAL A . n A 1 386 LYS 386 386 386 LYS LYS A . n A 1 387 PHE 387 387 387 PHE PHE A . n A 1 388 ASN 388 388 388 ASN ASN A . n A 1 389 TYR 389 389 389 TYR TYR A . n A 1 390 TYR 390 390 390 TYR TYR A . n A 1 391 SER 391 391 391 SER SER A . n A 1 392 ASN 392 392 392 ASN ASN A . n A 1 393 LEU 393 393 393 LEU LEU A . n A 1 394 THR 394 394 394 THR THR A . n A 1 395 ASP 395 395 395 ASP ASP A . n A 1 396 LEU 396 396 396 LEU LEU A . n A 1 397 SER 397 397 397 SER SER A . n A 1 398 HIS 398 398 398 HIS HIS A . n A 1 399 CYS 399 399 399 CYS CYS A . n A 1 400 VAL 400 400 400 VAL VAL A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 MET 403 403 403 MET MET A . n A 1 404 LYS 404 404 404 LYS LYS A . n A 1 405 LYS 405 405 405 LYS LYS A . n A 1 406 ILE 406 406 406 ILE ILE A . n A 1 407 GLY 407 407 407 GLY GLY A . n A 1 408 GLU 408 408 408 GLU GLU A . n A 1 409 LEU 409 409 409 LEU LEU A . n A 1 410 LEU 410 410 410 LEU LEU A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 THR 412 412 412 THR THR A . n A 1 413 ASP 413 413 413 ASP ASP A . n A 1 414 ALA 414 414 414 ALA ALA A . n A 1 415 LEU 415 415 415 LEU LEU A . n A 1 416 LYS 416 416 416 LYS LYS A . n A 1 417 PRO 417 417 417 PRO PRO A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 LYS 419 419 419 LYS LYS A . n A 1 420 VAL 420 420 420 VAL VAL A . n A 1 421 GLU 421 421 421 GLU GLU A . n A 1 422 ASP 422 422 422 ASP ASP A . n A 1 423 LEU 423 423 423 LEU LEU A . n A 1 424 PRO 424 424 424 PRO PRO A . n A 1 425 GLY 425 425 425 GLY GLY A . n A 1 426 VAL 426 426 426 VAL VAL A . n A 1 427 GLU 427 427 427 GLU GLU A . n A 1 428 GLY 428 428 428 GLY GLY A . n A 1 429 PHE 429 429 429 PHE PHE A . n A 1 430 ASN 430 430 430 ASN ASN A . n A 1 431 ILE 431 431 431 ILE ILE A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 GLY 433 433 433 GLY GLY A . n A 1 434 ILE 434 434 434 ILE ILE A . n A 1 435 PRO 435 435 435 PRO PRO A . n A 1 436 LEU 436 436 436 LEU LEU A . n A 1 437 PRO 437 437 437 PRO PRO A . n A 1 438 LYS 438 438 438 LYS LYS A . n A 1 439 ASP 439 439 439 ASP ASP A . n A 1 440 GLN 440 440 440 GLN GLN A . n A 1 441 THR 441 441 441 THR THR A . n A 1 442 ASP 442 442 442 ASP ASP A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 ALA 445 445 445 ALA ALA A . n A 1 446 PHE 446 446 446 PHE PHE A . n A 1 447 GLU 447 447 447 GLU GLU A . n A 1 448 THR 448 448 448 THR THR A . n A 1 449 PHE 449 449 449 PHE PHE A . n A 1 450 CYS 450 450 450 CYS CYS A . n A 1 451 ARG 451 451 451 ARG ARG A . n A 1 452 GLU 452 452 452 GLU GLU A . n A 1 453 SER 453 453 453 SER SER A . n A 1 454 VAL 454 454 454 VAL VAL A . n A 1 455 ALA 455 455 455 ALA ALA A . n A 1 456 SER 456 456 456 SER SER A . n A 1 457 TYR 457 457 457 TYR TYR A . n A 1 458 TRP 458 458 458 TRP TRP A . n A 1 459 HIS 459 459 459 HIS HIS A . n A 1 460 TYR 460 460 460 TYR TYR A . n A 1 461 HIS 461 461 461 HIS HIS A . n A 1 462 GLY 462 462 462 GLY GLY A . n A 1 463 GLY 463 463 463 GLY GLY A . n A 1 464 CYS 464 464 464 CYS CYS A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 VAL 466 466 466 VAL VAL A . n A 1 467 GLY 467 467 467 GLY GLY A . n A 1 468 LYS 468 468 468 LYS LYS A . n A 1 469 VAL 469 469 469 VAL VAL A . n A 1 470 LEU 470 470 470 LEU LEU A . n A 1 471 ASP 471 471 471 ASP ASP A . n A 1 472 GLY 472 472 472 GLY GLY A . n A 1 473 ASP 473 473 473 ASP ASP A . n A 1 474 PHE 474 474 474 PHE PHE A . n A 1 475 ARG 475 475 475 ARG ARG A . n A 1 476 VAL 476 476 476 VAL VAL A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 GLY 478 478 478 GLY GLY A . n A 1 479 ILE 479 479 479 ILE ILE A . n A 1 480 ASN 480 480 480 ASN ASN A . n A 1 481 ALA 481 481 481 ALA ALA A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 ARG 483 483 483 ARG ARG A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 VAL 485 485 485 VAL VAL A . n A 1 486 ASP 486 486 486 ASP ASP A . n A 1 487 GLY 487 487 487 GLY GLY A . n A 1 488 SER 488 488 488 SER SER A . n A 1 489 THR 489 489 489 THR THR A . n A 1 490 PHE 490 490 490 PHE PHE A . n A 1 491 PRO 491 491 491 PRO PRO A . n A 1 492 TYR 492 492 492 TYR TYR A . n A 1 493 THR 493 493 493 THR THR A . n A 1 494 PRO 494 494 494 PRO PRO A . n A 1 495 ALA 495 495 495 ALA ALA A . n A 1 496 SER 496 496 496 SER SER A . n A 1 497 HIS 497 497 497 HIS HIS A . n A 1 498 PRO 498 498 498 PRO PRO A . n A 1 499 GLN 499 499 499 GLN GLN A . n A 1 500 GLY 500 500 500 GLY GLY A . n A 1 501 PHE 501 501 501 PHE PHE A . n A 1 502 TYR 502 502 502 TYR TYR A . n A 1 503 LEU 503 503 503 LEU LEU A . n A 1 504 MET 504 504 504 MET MET A . n A 1 505 LEU 505 505 505 LEU LEU A . n A 1 506 GLY 506 506 506 GLY GLY A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 TYR 508 508 508 TYR TYR A . n A 1 509 VAL 509 509 509 VAL VAL A . n A 1 510 GLY 510 510 510 GLY GLY A . n A 1 511 ILE 511 511 511 ILE ILE A . n A 1 512 LYS 512 512 512 LYS LYS A . n A 1 513 ILE 513 513 513 ILE ILE A . n A 1 514 LEU 514 514 514 LEU LEU A . n A 1 515 GLN 515 515 515 GLN GLN A . n A 1 516 GLU 516 516 516 GLU GLU A . n A 1 517 ARG 517 517 517 ARG ARG A . n A 1 518 SER 518 518 518 SER SER A . n A 1 519 ALA 519 519 519 ALA ALA A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 ASP 521 521 521 ASP ASP A . n B 1 1 LEU 1 1 1 LEU LEU B . n B 1 2 ALA 2 2 2 ALA ALA B . n B 1 3 THR 3 3 3 THR THR B . n B 1 4 THR 4 4 4 THR THR B . n B 1 5 SER 5 5 5 SER SER B . n B 1 6 ASP 6 6 6 ASP ASP B . n B 1 7 HIS 7 7 7 HIS HIS B . n B 1 8 ASP 8 8 8 ASP ASP B . n B 1 9 PHE 9 9 9 PHE PHE B . n B 1 10 SER 10 10 10 SER SER B . n B 1 11 TYR 11 11 11 TYR TYR B . n B 1 12 LEU 12 12 12 LEU LEU B . n B 1 13 SER 13 13 13 SER SER B . n B 1 14 PHE 14 14 14 PHE PHE B . n B 1 15 ALA 15 15 15 ALA ALA B . n B 1 16 TYR 16 16 16 TYR TYR B . n B 1 17 ASP 17 17 17 ASP ASP B . n B 1 18 ALA 18 18 18 ALA ALA B . n B 1 19 THR 19 19 19 THR THR B . n B 1 20 ASP 20 20 20 ASP ASP B . n B 1 21 LEU 21 21 21 LEU LEU B . n B 1 22 GLU 22 22 22 GLU GLU B . n B 1 23 LEU 23 23 23 LEU LEU B . n B 1 24 GLU 24 24 24 GLU GLU B . n B 1 25 GLY 25 25 25 GLY GLY B . n B 1 26 SER 26 26 26 SER SER B . n B 1 27 TYR 27 27 27 TYR TYR B . n B 1 28 ASP 28 28 28 ASP ASP B . n B 1 29 TYR 29 29 29 TYR TYR B . n B 1 30 VAL 30 30 30 VAL VAL B . n B 1 31 ILE 31 31 31 ILE ILE B . n B 1 32 VAL 32 32 32 VAL VAL B . n B 1 33 GLY 33 33 33 GLY GLY B . n B 1 34 GLY 34 34 34 GLY GLY B . n B 1 35 GLY 35 35 35 GLY GLY B . n B 1 36 THR 36 36 36 THR THR B . n B 1 37 SER 37 37 37 SER SER B . n B 1 38 GLY 38 38 38 GLY GLY B . n B 1 39 CYS 39 39 39 CYS CYS B . n B 1 40 PRO 40 40 40 PRO PRO B . n B 1 41 LEU 41 41 41 LEU LEU B . n B 1 42 ALA 42 42 42 ALA ALA B . n B 1 43 ALA 43 43 43 ALA ALA B . n B 1 44 THR 44 44 44 THR THR B . n B 1 45 LEU 45 45 45 LEU LEU B . n B 1 46 SER 46 46 46 SER SER B . n B 1 47 GLU 47 47 47 GLU GLU B . n B 1 48 LYS 48 48 48 LYS LYS B . n B 1 49 TYR 49 49 49 TYR TYR B . n B 1 50 LYS 50 50 50 LYS LYS B . n B 1 51 VAL 51 51 51 VAL VAL B . n B 1 52 LEU 52 52 52 LEU LEU B . n B 1 53 VAL 53 53 53 VAL VAL B . n B 1 54 LEU 54 54 54 LEU LEU B . n B 1 55 GLU 55 55 55 GLU GLU B . n B 1 56 ARG 56 56 56 ARG ARG B . n B 1 57 GLY 57 57 57 GLY GLY B . n B 1 58 SER 58 58 58 SER SER B . n B 1 59 LEU 59 59 59 LEU LEU B . n B 1 60 PRO 60 60 60 PRO PRO B . n B 1 61 THR 61 61 61 THR THR B . n B 1 62 ALA 62 62 62 ALA ALA B . n B 1 63 TYR 63 63 63 TYR TYR B . n B 1 64 PRO 64 64 64 PRO PRO B . n B 1 65 ASN 65 65 65 ASN ASN B . n B 1 66 VAL 66 66 66 VAL VAL B . n B 1 67 LEU 67 67 67 LEU LEU B . n B 1 68 THR 68 68 68 THR THR B . n B 1 69 ALA 69 69 69 ALA ALA B . n B 1 70 ASP 70 70 70 ASP ASP B . n B 1 71 GLY 71 71 71 GLY GLY B . n B 1 72 PHE 72 72 72 PHE PHE B . n B 1 73 VAL 73 73 73 VAL VAL B . n B 1 74 TYR 74 74 74 TYR TYR B . n B 1 75 ASN 75 75 75 ASN ASN B . n B 1 76 LEU 76 76 76 LEU LEU B . n B 1 77 GLN 77 77 77 GLN GLN B . n B 1 78 GLN 78 78 78 GLN GLN B . n B 1 79 GLU 79 79 79 GLU GLU B . n B 1 80 ASP 80 80 80 ASP ASP B . n B 1 81 ASP 81 81 81 ASP ASP B . n B 1 82 GLY 82 82 82 GLY GLY B . n B 1 83 LYS 83 83 83 LYS LYS B . n B 1 84 THR 84 84 84 THR THR B . n B 1 85 PRO 85 85 85 PRO PRO B . n B 1 86 VAL 86 86 86 VAL VAL B . n B 1 87 GLU 87 87 87 GLU GLU B . n B 1 88 ARG 88 88 88 ARG ARG B . n B 1 89 PHE 89 89 89 PHE PHE B . n B 1 90 VAL 90 90 90 VAL VAL B . n B 1 91 SER 91 91 91 SER SER B . n B 1 92 GLU 92 92 92 GLU GLU B . n B 1 93 ASP 93 93 93 ASP ASP B . n B 1 94 GLY 94 94 94 GLY GLY B . n B 1 95 ILE 95 95 95 ILE ILE B . n B 1 96 ASP 96 96 96 ASP ASP B . n B 1 97 ASN 97 97 97 ASN ASN B . n B 1 98 VAL 98 98 98 VAL VAL B . n B 1 99 ARG 99 99 99 ARG ARG B . n B 1 100 GLY 100 100 100 GLY GLY B . n B 1 101 ARG 101 101 101 ARG ARG B . n B 1 102 VAL 102 102 102 VAL VAL B . n B 1 103 LEU 103 103 103 LEU LEU B . n B 1 104 GLY 104 104 104 GLY GLY B . n B 1 105 GLY 105 105 105 GLY GLY B . n B 1 106 THR 106 106 106 THR THR B . n B 1 107 SER 107 107 107 SER SER B . n B 1 108 ILE 108 108 108 ILE ILE B . n B 1 109 ILE 109 109 109 ILE ILE B . n B 1 110 ASN 110 110 110 ASN ASN B . n B 1 111 ALA 111 111 111 ALA ALA B . n B 1 112 GLY 112 112 112 GLY GLY B . n B 1 113 VAL 113 113 113 VAL VAL B . n B 1 114 TYR 114 114 114 TYR TYR B . n B 1 115 ALA 115 115 115 ALA ALA B . n B 1 116 ARG 116 116 116 ARG ARG B . n B 1 117 ALA 117 117 117 ALA ALA B . n B 1 118 ASN 118 118 118 ASN ASN B . n B 1 119 THR 119 119 119 THR THR B . n B 1 120 SER 120 120 120 SER SER B . n B 1 121 ILE 121 121 121 ILE ILE B . n B 1 122 TYR 122 122 122 TYR TYR B . n B 1 123 SER 123 123 123 SER SER B . n B 1 124 ALA 124 124 124 ALA ALA B . n B 1 125 SER 125 125 125 SER SER B . n B 1 126 GLY 126 126 126 GLY GLY B . n B 1 127 VAL 127 127 127 VAL VAL B . n B 1 128 ASP 128 128 128 ASP ASP B . n B 1 129 TRP 129 129 129 TRP TRP B . n B 1 130 ASP 130 130 130 ASP ASP B . n B 1 131 MET 131 131 131 MET MET B . n B 1 132 ASP 132 132 132 ASP ASP B . n B 1 133 LEU 133 133 133 LEU LEU B . n B 1 134 VAL 134 134 134 VAL VAL B . n B 1 135 ASN 135 135 135 ASN ASN B . n B 1 136 GLN 136 136 136 GLN GLN B . n B 1 137 THR 137 137 137 THR THR B . n B 1 138 TYR 138 138 138 TYR TYR B . n B 1 139 GLU 139 139 139 GLU GLU B . n B 1 140 TRP 140 140 140 TRP TRP B . n B 1 141 VAL 141 141 141 VAL VAL B . n B 1 142 GLU 142 142 142 GLU GLU B . n B 1 143 ASP 143 143 143 ASP ASP B . n B 1 144 THR 144 144 144 THR THR B . n B 1 145 ILE 145 145 145 ILE ILE B . n B 1 146 VAL 146 146 146 VAL VAL B . n B 1 147 TYR 147 147 147 TYR TYR B . n B 1 148 LYS 148 148 148 LYS LYS B . n B 1 149 PRO 149 149 149 PRO PRO B . n B 1 150 ASN 150 150 150 ASN ASN B . n B 1 151 SER 151 151 151 SER SER B . n B 1 152 GLN 152 152 152 GLN GLN B . n B 1 153 SER 153 153 153 SER SER B . n B 1 154 TRP 154 154 154 TRP TRP B . n B 1 155 GLN 155 155 155 GLN GLN B . n B 1 156 SER 156 156 156 SER SER B . n B 1 157 VAL 157 157 157 VAL VAL B . n B 1 158 THR 158 158 158 THR THR B . n B 1 159 LYS 159 159 159 LYS LYS B . n B 1 160 THR 160 160 160 THR THR B . n B 1 161 ALA 161 161 161 ALA ALA B . n B 1 162 PHE 162 162 162 PHE PHE B . n B 1 163 LEU 163 163 163 LEU LEU B . n B 1 164 GLU 164 164 164 GLU GLU B . n B 1 165 ALA 165 165 165 ALA ALA B . n B 1 166 GLY 166 166 166 GLY GLY B . n B 1 167 VAL 167 167 167 VAL VAL B . n B 1 168 HIS 168 168 168 HIS HIS B . n B 1 169 PRO 169 169 169 PRO PRO B . n B 1 170 ASN 170 170 170 ASN ASN B . n B 1 171 HIS 171 171 171 HIS HIS B . n B 1 172 GLY 172 172 172 GLY GLY B . n B 1 173 PHE 173 173 173 PHE PHE B . n B 1 174 SER 174 174 174 SER SER B . n B 1 175 LEU 175 175 175 LEU LEU B . n B 1 176 ASP 176 176 176 ASP ASP B . n B 1 177 HIS 177 177 177 HIS HIS B . n B 1 178 GLU 178 178 178 GLU GLU B . n B 1 179 GLU 179 179 179 GLU GLU B . n B 1 180 GLY 180 180 180 GLY GLY B . n B 1 181 THR 181 181 181 THR THR B . n B 1 182 ARG 182 182 182 ARG ARG B . n B 1 183 ILE 183 183 183 ILE ILE B . n B 1 184 THR 184 184 184 THR THR B . n B 1 185 GLY 185 185 185 GLY GLY B . n B 1 186 SER 186 186 186 SER SER B . n B 1 187 THR 187 187 187 THR THR B . n B 1 188 PHE 188 188 188 PHE PHE B . n B 1 189 ASP 189 189 189 ASP ASP B . n B 1 190 ASN 190 190 190 ASN ASN B . n B 1 191 LYS 191 191 191 LYS LYS B . n B 1 192 GLY 192 192 192 GLY GLY B . n B 1 193 THR 193 193 193 THR THR B . n B 1 194 ARG 194 194 194 ARG ARG B . n B 1 195 HIS 195 195 195 HIS HIS B . n B 1 196 ALA 196 196 196 ALA ALA B . n B 1 197 ALA 197 197 197 ALA ALA B . n B 1 198 ASP 198 198 198 ASP ASP B . n B 1 199 GLU 199 199 199 GLU GLU B . n B 1 200 LEU 200 200 200 LEU LEU B . n B 1 201 LEU 201 201 201 LEU LEU B . n B 1 202 ASN 202 202 202 ASN ASN B . n B 1 203 LYS 203 203 203 LYS LYS B . n B 1 204 GLY 204 204 204 GLY GLY B . n B 1 205 ASN 205 205 205 ASN ASN B . n B 1 206 SER 206 206 206 SER SER B . n B 1 207 ASN 207 207 207 ASN ASN B . n B 1 208 ASN 208 208 208 ASN ASN B . n B 1 209 LEU 209 209 209 LEU LEU B . n B 1 210 ARG 210 210 210 ARG ARG B . n B 1 211 VAL 211 211 211 VAL VAL B . n B 1 212 GLY 212 212 212 GLY GLY B . n B 1 213 VAL 213 213 213 VAL VAL B . n B 1 214 HIS 214 214 214 HIS HIS B . n B 1 215 ALA 215 215 215 ALA ALA B . n B 1 216 SER 216 216 216 SER SER B . n B 1 217 VAL 217 217 217 VAL VAL B . n B 1 218 GLU 218 218 218 GLU GLU B . n B 1 219 LYS 219 219 219 LYS LYS B . n B 1 220 ILE 220 220 220 ILE ILE B . n B 1 221 ILE 221 221 221 ILE ILE B . n B 1 222 PHE 222 222 222 PHE PHE B . n B 1 223 SER 223 223 223 SER SER B . n B 1 224 ASN 224 224 224 ASN ASN B . n B 1 225 ALA 225 225 225 ALA ALA B . n B 1 226 PRO 226 226 226 PRO PRO B . n B 1 227 GLY 227 227 227 GLY GLY B . n B 1 228 LEU 228 228 228 LEU LEU B . n B 1 229 THR 229 229 229 THR THR B . n B 1 230 ALA 230 230 230 ALA ALA B . n B 1 231 THR 231 231 231 THR THR B . n B 1 232 GLY 232 232 232 GLY GLY B . n B 1 233 VAL 233 233 233 VAL VAL B . n B 1 234 ILE 234 234 234 ILE ILE B . n B 1 235 TYR 235 235 235 TYR TYR B . n B 1 236 ARG 236 236 236 ARG ARG B . n B 1 237 ASP 237 237 237 ASP ASP B . n B 1 238 SER 238 238 238 SER SER B . n B 1 239 ASN 239 239 239 ASN ASN B . n B 1 240 GLY 240 240 240 GLY GLY B . n B 1 241 THR 241 241 241 THR THR B . n B 1 242 PRO 242 242 242 PRO PRO B . n B 1 243 HIS 243 243 243 HIS HIS B . n B 1 244 GLN 244 244 244 GLN GLN B . n B 1 245 ALA 245 245 245 ALA ALA B . n B 1 246 PHE 246 246 246 PHE PHE B . n B 1 247 VAL 247 247 247 VAL VAL B . n B 1 248 ARG 248 248 248 ARG ARG B . n B 1 249 SER 249 249 249 SER SER B . n B 1 250 LYS 250 250 250 LYS LYS B . n B 1 251 GLY 251 251 251 GLY GLY B . n B 1 252 GLU 252 252 252 GLU GLU B . n B 1 253 VAL 253 253 253 VAL VAL B . n B 1 254 ILE 254 254 254 ILE ILE B . n B 1 255 VAL 255 255 255 VAL VAL B . n B 1 256 SER 256 256 256 SER SER B . n B 1 257 ALA 257 257 257 ALA ALA B . n B 1 258 GLY 258 258 258 GLY GLY B . n B 1 259 THR 259 259 259 THR THR B . n B 1 260 ILE 260 260 260 ILE ILE B . n B 1 261 GLY 261 261 261 GLY GLY B . n B 1 262 THR 262 262 262 THR THR B . n B 1 263 PRO 263 263 263 PRO PRO B . n B 1 264 GLN 264 264 264 GLN GLN B . n B 1 265 LEU 265 265 265 LEU LEU B . n B 1 266 LEU 266 266 266 LEU LEU B . n B 1 267 LEU 267 267 267 LEU LEU B . n B 1 268 LEU 268 268 268 LEU LEU B . n B 1 269 SER 269 269 269 SER SER B . n B 1 270 GLY 270 270 270 GLY GLY B . n B 1 271 VAL 271 271 271 VAL VAL B . n B 1 272 GLY 272 272 272 GLY GLY B . n B 1 273 PRO 273 273 273 PRO PRO B . n B 1 274 GLU 274 274 274 GLU GLU B . n B 1 275 SER 275 275 275 SER SER B . n B 1 276 TYR 276 276 276 TYR TYR B . n B 1 277 LEU 277 277 277 LEU LEU B . n B 1 278 SER 278 278 278 SER SER B . n B 1 279 SER 279 279 279 SER SER B . n B 1 280 LEU 280 280 280 LEU LEU B . n B 1 281 ASN 281 281 281 ASN ASN B . n B 1 282 ILE 282 282 282 ILE ILE B . n B 1 283 PRO 283 283 283 PRO PRO B . n B 1 284 VAL 284 284 284 VAL VAL B . n B 1 285 VAL 285 285 285 VAL VAL B . n B 1 286 LEU 286 286 286 LEU LEU B . n B 1 287 SER 287 287 287 SER SER B . n B 1 288 HIS 288 288 288 HIS HIS B . n B 1 289 PRO 289 289 289 PRO PRO B . n B 1 290 TYR 290 290 290 TYR TYR B . n B 1 291 VAL 291 291 291 VAL VAL B . n B 1 292 GLY 292 292 292 GLY GLY B . n B 1 293 GLN 293 293 293 GLN GLN B . n B 1 294 PHE 294 294 294 PHE PHE B . n B 1 295 LEU 295 295 295 LEU LEU B . n B 1 296 HIS 296 296 296 HIS HIS B . n B 1 297 ASP 297 297 297 ASP ASP B . n B 1 298 ASN 298 298 298 ASN ASN B . n B 1 299 PRO 299 299 299 PRO PRO B . n B 1 300 ARG 300 300 300 ARG ARG B . n B 1 301 ASN 301 301 301 ASN ASN B . n B 1 302 PHE 302 302 302 PHE PHE B . n B 1 303 ILE 303 303 303 ILE ILE B . n B 1 304 ASN 304 304 304 ASN ASN B . n B 1 305 ILE 305 305 305 ILE ILE B . n B 1 306 LEU 306 306 306 LEU LEU B . n B 1 307 PRO 307 307 307 PRO PRO B . n B 1 308 PRO 308 308 308 PRO PRO B . n B 1 309 ASN 309 309 309 ASN ASN B . n B 1 310 PRO 310 310 310 PRO PRO B . n B 1 311 ILE 311 311 311 ILE ILE B . n B 1 312 GLU 312 312 312 GLU GLU B . n B 1 313 PRO 313 313 313 PRO PRO B . n B 1 314 THR 314 314 314 THR THR B . n B 1 315 ILE 315 315 315 ILE ILE B . n B 1 316 VAL 316 316 316 VAL VAL B . n B 1 317 THR 317 317 317 THR THR B . n B 1 318 VAL 318 318 318 VAL VAL B . n B 1 319 LEU 319 319 319 LEU LEU B . n B 1 320 GLY 320 320 320 GLY GLY B . n B 1 321 ILE 321 321 321 ILE ILE B . n B 1 322 SER 322 322 322 SER SER B . n B 1 323 ASN 323 323 323 ASN ASN B . n B 1 324 ASP 324 324 324 ASP ASP B . n B 1 325 PHE 325 325 325 PHE PHE B . n B 1 326 TYR 326 326 326 TYR TYR B . n B 1 327 GLN 327 327 327 GLN GLN B . n B 1 328 CYS 328 328 328 CYS CYS B . n B 1 329 SER 329 329 329 SER SER B . n B 1 330 PHE 330 330 330 PHE PHE B . n B 1 331 SER 331 331 331 SER SER B . n B 1 332 SER 332 332 332 SER SER B . n B 1 333 LEU 333 333 333 LEU LEU B . n B 1 334 PRO 334 334 334 PRO PRO B . n B 1 335 PHE 335 335 335 PHE PHE B . n B 1 336 THR 336 336 336 THR THR B . n B 1 337 THR 337 337 337 THR THR B . n B 1 338 PRO 338 338 338 PRO PRO B . n B 1 339 PRO 339 339 339 PRO PRO B . n B 1 340 PHE 340 340 340 PHE PHE B . n B 1 341 GLY 341 341 341 GLY GLY B . n B 1 342 PHE 342 342 342 PHE PHE B . n B 1 343 PHE 343 343 343 PHE PHE B . n B 1 344 PRO 344 344 344 PRO PRO B . n B 1 345 SER 345 345 345 SER SER B . n B 1 346 SER 346 346 346 SER SER B . n B 1 347 SER 347 347 347 SER SER B . n B 1 348 TYR 348 348 348 TYR TYR B . n B 1 349 PRO 349 349 349 PRO PRO B . n B 1 350 LEU 350 350 350 LEU LEU B . n B 1 351 PRO 351 351 351 PRO PRO B . n B 1 352 ASN 352 352 352 ASN ASN B . n B 1 353 SER 353 353 353 SER SER B . n B 1 354 THR 354 354 354 THR THR B . n B 1 355 PHE 355 355 355 PHE PHE B . n B 1 356 ALA 356 356 356 ALA ALA B . n B 1 357 HIS 357 357 357 HIS HIS B . n B 1 358 PHE 358 358 358 PHE PHE B . n B 1 359 ALA 359 359 359 ALA ALA B . n B 1 360 SER 360 360 360 SER SER B . n B 1 361 LYS 361 361 361 LYS LYS B . n B 1 362 VAL 362 362 362 VAL VAL B . n B 1 363 ALA 363 363 363 ALA ALA B . n B 1 364 GLY 364 364 364 GLY GLY B . n B 1 365 PRO 365 365 365 PRO PRO B . n B 1 366 LEU 366 366 366 LEU LEU B . n B 1 367 SER 367 367 367 SER SER B . n B 1 368 TYR 368 368 368 TYR TYR B . n B 1 369 GLY 369 369 369 GLY GLY B . n B 1 370 SER 370 370 370 SER SER B . n B 1 371 LEU 371 371 371 LEU LEU B . n B 1 372 THR 372 372 372 THR THR B . n B 1 373 LEU 373 373 373 LEU LEU B . n B 1 374 LYS 374 374 374 LYS LYS B . n B 1 375 SER 375 375 375 SER SER B . n B 1 376 SER 376 376 376 SER SER B . n B 1 377 SER 377 377 377 SER SER B . n B 1 378 ASN 378 378 378 ASN ASN B . n B 1 379 VAL 379 379 379 VAL VAL B . n B 1 380 ARG 380 380 380 ARG ARG B . n B 1 381 VAL 381 381 381 VAL VAL B . n B 1 382 SER 382 382 382 SER SER B . n B 1 383 PRO 383 383 383 PRO PRO B . n B 1 384 ASN 384 384 384 ASN ASN B . n B 1 385 VAL 385 385 385 VAL VAL B . n B 1 386 LYS 386 386 386 LYS LYS B . n B 1 387 PHE 387 387 387 PHE PHE B . n B 1 388 ASN 388 388 388 ASN ASN B . n B 1 389 TYR 389 389 389 TYR TYR B . n B 1 390 TYR 390 390 390 TYR TYR B . n B 1 391 SER 391 391 391 SER SER B . n B 1 392 ASN 392 392 392 ASN ASN B . n B 1 393 LEU 393 393 393 LEU LEU B . n B 1 394 THR 394 394 394 THR THR B . n B 1 395 ASP 395 395 395 ASP ASP B . n B 1 396 LEU 396 396 396 LEU LEU B . n B 1 397 SER 397 397 397 SER SER B . n B 1 398 HIS 398 398 398 HIS HIS B . n B 1 399 CYS 399 399 399 CYS CYS B . n B 1 400 VAL 400 400 400 VAL VAL B . n B 1 401 SER 401 401 401 SER SER B . n B 1 402 GLY 402 402 402 GLY GLY B . n B 1 403 MET 403 403 403 MET MET B . n B 1 404 LYS 404 404 404 LYS LYS B . n B 1 405 LYS 405 405 405 LYS LYS B . n B 1 406 ILE 406 406 406 ILE ILE B . n B 1 407 GLY 407 407 407 GLY GLY B . n B 1 408 GLU 408 408 408 GLU GLU B . n B 1 409 LEU 409 409 409 LEU LEU B . n B 1 410 LEU 410 410 410 LEU LEU B . n B 1 411 SER 411 411 411 SER SER B . n B 1 412 THR 412 412 412 THR THR B . n B 1 413 ASP 413 413 413 ASP ASP B . n B 1 414 ALA 414 414 414 ALA ALA B . n B 1 415 LEU 415 415 415 LEU LEU B . n B 1 416 LYS 416 416 416 LYS LYS B . n B 1 417 PRO 417 417 417 PRO PRO B . n B 1 418 TYR 418 418 418 TYR TYR B . n B 1 419 LYS 419 419 419 LYS LYS B . n B 1 420 VAL 420 420 420 VAL VAL B . n B 1 421 GLU 421 421 421 GLU GLU B . n B 1 422 ASP 422 422 422 ASP ASP B . n B 1 423 LEU 423 423 423 LEU LEU B . n B 1 424 PRO 424 424 424 PRO PRO B . n B 1 425 GLY 425 425 425 GLY GLY B . n B 1 426 VAL 426 426 426 VAL VAL B . n B 1 427 GLU 427 427 427 GLU GLU B . n B 1 428 GLY 428 428 428 GLY GLY B . n B 1 429 PHE 429 429 429 PHE PHE B . n B 1 430 ASN 430 430 430 ASN ASN B . n B 1 431 ILE 431 431 431 ILE ILE B . n B 1 432 LEU 432 432 432 LEU LEU B . n B 1 433 GLY 433 433 433 GLY GLY B . n B 1 434 ILE 434 434 434 ILE ILE B . n B 1 435 PRO 435 435 435 PRO PRO B . n B 1 436 LEU 436 436 436 LEU LEU B . n B 1 437 PRO 437 437 437 PRO PRO B . n B 1 438 LYS 438 438 438 LYS LYS B . n B 1 439 ASP 439 439 439 ASP ASP B . n B 1 440 GLN 440 440 440 GLN GLN B . n B 1 441 THR 441 441 441 THR THR B . n B 1 442 ASP 442 442 442 ASP ASP B . n B 1 443 ASP 443 443 443 ASP ASP B . n B 1 444 ALA 444 444 444 ALA ALA B . n B 1 445 ALA 445 445 445 ALA ALA B . n B 1 446 PHE 446 446 446 PHE PHE B . n B 1 447 GLU 447 447 447 GLU GLU B . n B 1 448 THR 448 448 448 THR THR B . n B 1 449 PHE 449 449 449 PHE PHE B . n B 1 450 CYS 450 450 450 CYS CYS B . n B 1 451 ARG 451 451 451 ARG ARG B . n B 1 452 GLU 452 452 452 GLU GLU B . n B 1 453 SER 453 453 453 SER SER B . n B 1 454 VAL 454 454 454 VAL VAL B . n B 1 455 ALA 455 455 455 ALA ALA B . n B 1 456 SER 456 456 456 SER SER B . n B 1 457 TYR 457 457 457 TYR TYR B . n B 1 458 TRP 458 458 458 TRP TRP B . n B 1 459 HIS 459 459 459 HIS HIS B . n B 1 460 TYR 460 460 460 TYR TYR B . n B 1 461 HIS 461 461 461 HIS HIS B . n B 1 462 GLY 462 462 462 GLY GLY B . n B 1 463 GLY 463 463 463 GLY GLY B . n B 1 464 CYS 464 464 464 CYS CYS B . n B 1 465 LEU 465 465 465 LEU LEU B . n B 1 466 VAL 466 466 466 VAL VAL B . n B 1 467 GLY 467 467 467 GLY GLY B . n B 1 468 LYS 468 468 468 LYS LYS B . n B 1 469 VAL 469 469 469 VAL VAL B . n B 1 470 LEU 470 470 470 LEU LEU B . n B 1 471 ASP 471 471 471 ASP ASP B . n B 1 472 GLY 472 472 472 GLY GLY B . n B 1 473 ASP 473 473 473 ASP ASP B . n B 1 474 PHE 474 474 474 PHE PHE B . n B 1 475 ARG 475 475 475 ARG ARG B . n B 1 476 VAL 476 476 476 VAL VAL B . n B 1 477 THR 477 477 477 THR THR B . n B 1 478 GLY 478 478 478 GLY GLY B . n B 1 479 ILE 479 479 479 ILE ILE B . n B 1 480 ASN 480 480 480 ASN ASN B . n B 1 481 ALA 481 481 481 ALA ALA B . n B 1 482 LEU 482 482 482 LEU LEU B . n B 1 483 ARG 483 483 483 ARG ARG B . n B 1 484 VAL 484 484 484 VAL VAL B . n B 1 485 VAL 485 485 485 VAL VAL B . n B 1 486 ASP 486 486 486 ASP ASP B . n B 1 487 GLY 487 487 487 GLY GLY B . n B 1 488 SER 488 488 488 SER SER B . n B 1 489 THR 489 489 489 THR THR B . n B 1 490 PHE 490 490 490 PHE PHE B . n B 1 491 PRO 491 491 491 PRO PRO B . n B 1 492 TYR 492 492 492 TYR TYR B . n B 1 493 THR 493 493 493 THR THR B . n B 1 494 PRO 494 494 494 PRO PRO B . n B 1 495 ALA 495 495 495 ALA ALA B . n B 1 496 SER 496 496 496 SER SER B . n B 1 497 HIS 497 497 497 HIS HIS B . n B 1 498 PRO 498 498 498 PRO PRO B . n B 1 499 GLN 499 499 499 GLN GLN B . n B 1 500 GLY 500 500 500 GLY GLY B . n B 1 501 PHE 501 501 501 PHE PHE B . n B 1 502 TYR 502 502 502 TYR TYR B . n B 1 503 LEU 503 503 503 LEU LEU B . n B 1 504 MET 504 504 504 MET MET B . n B 1 505 LEU 505 505 505 LEU LEU B . n B 1 506 GLY 506 506 506 GLY GLY B . n B 1 507 ARG 507 507 507 ARG ARG B . n B 1 508 TYR 508 508 508 TYR TYR B . n B 1 509 VAL 509 509 509 VAL VAL B . n B 1 510 GLY 510 510 510 GLY GLY B . n B 1 511 ILE 511 511 511 ILE ILE B . n B 1 512 LYS 512 512 512 LYS LYS B . n B 1 513 ILE 513 513 513 ILE ILE B . n B 1 514 LEU 514 514 514 LEU LEU B . n B 1 515 GLN 515 515 515 GLN GLN B . n B 1 516 GLU 516 516 516 GLU GLU B . n B 1 517 ARG 517 517 517 ARG ARG B . n B 1 518 SER 518 518 518 SER SER B . n B 1 519 ALA 519 519 519 ALA ALA B . n B 1 520 SER 520 520 520 SER SER B . n B 1 521 ASP 521 521 521 ASP ASP B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 IPA 1 522 522 IPA IPA A . D 3 FAD 1 523 523 FAD FAD A . E 4 NAG 1 524 524 NAG NAG A . F 4 NAG 1 525 525 NAG NAG A . G 4 NAG 2 526 526 NAG NAG A . H 5 FUL 3 527 527 FUL FUL A . I 6 MAN 4 528 528 MAN MAN A . J 6 MAN 5 529 529 MAN MAN A . K 4 NAG 1 530 530 NAG NAG A . L 4 NAG 2 531 531 NAG NAG A . M 7 FUC 3 532 532 FUC FUC A . N 4 NAG 1 533 533 NAG NAG A . O 2 IPA 1 522 522 IPA IPA B . P 3 FAD 1 523 523 FAD FAD B . Q 4 NAG 1 524 524 NAG NAG B . R 4 NAG 2 525 525 NAG NAG B . S 7 FUC 3 526 526 FUC FUC B . T 8 BMA 4 527 527 BMA BMA B . U 6 MAN 5 528 528 MAN MAN B . V 4 NAG 1 529 529 NAG NAG B . W 4 NAG 2 530 530 NAG NAG B . X 8 BMA 3 531 531 BMA BMA B . Y 6 MAN 4 532 532 MAN MAN B . Z 9 NDG 1 533 533 NDG NDG B . AA 4 NAG 1 534 534 NAG NAG B . BA 10 HOH 1 534 534 HOH HOH A . BA 10 HOH 2 535 535 HOH HOH A . BA 10 HOH 3 536 536 HOH HOH A . BA 10 HOH 4 537 537 HOH HOH A . BA 10 HOH 5 538 538 HOH HOH A . BA 10 HOH 6 539 539 HOH HOH A . BA 10 HOH 7 540 540 HOH HOH A . BA 10 HOH 8 541 541 HOH HOH A . BA 10 HOH 9 542 542 HOH HOH A . BA 10 HOH 10 543 543 HOH HOH A . BA 10 HOH 11 544 544 HOH HOH A . BA 10 HOH 12 545 545 HOH HOH A . BA 10 HOH 13 546 546 HOH HOH A . BA 10 HOH 14 547 547 HOH HOH A . BA 10 HOH 15 548 548 HOH HOH A . BA 10 HOH 16 549 549 HOH HOH A . BA 10 HOH 17 550 550 HOH HOH A . BA 10 HOH 18 551 551 HOH HOH A . BA 10 HOH 19 552 552 HOH HOH A . BA 10 HOH 20 553 553 HOH HOH A . BA 10 HOH 21 554 554 HOH HOH A . BA 10 HOH 22 555 555 HOH HOH A . BA 10 HOH 23 556 556 HOH HOH A . BA 10 HOH 24 557 557 HOH HOH A . BA 10 HOH 25 558 558 HOH HOH A . BA 10 HOH 26 559 559 HOH HOH A . BA 10 HOH 27 560 560 HOH HOH A . BA 10 HOH 28 561 561 HOH HOH A . BA 10 HOH 29 562 562 HOH HOH A . BA 10 HOH 30 563 563 HOH HOH A . BA 10 HOH 31 564 564 HOH HOH A . BA 10 HOH 32 565 565 HOH HOH A . BA 10 HOH 33 566 566 HOH HOH A . BA 10 HOH 34 567 567 HOH HOH A . BA 10 HOH 35 568 568 HOH HOH A . BA 10 HOH 36 569 569 HOH HOH A . BA 10 HOH 37 570 570 HOH HOH A . BA 10 HOH 38 571 571 HOH HOH A . BA 10 HOH 39 572 572 HOH HOH A . BA 10 HOH 40 573 573 HOH HOH A . BA 10 HOH 41 574 574 HOH HOH A . BA 10 HOH 42 575 575 HOH HOH A . BA 10 HOH 43 576 576 HOH HOH A . BA 10 HOH 44 577 577 HOH HOH A . BA 10 HOH 45 578 578 HOH HOH A . BA 10 HOH 46 579 579 HOH HOH A . BA 10 HOH 47 580 580 HOH HOH A . BA 10 HOH 48 581 581 HOH HOH A . BA 10 HOH 49 582 582 HOH HOH A . BA 10 HOH 50 583 583 HOH HOH A . BA 10 HOH 51 584 584 HOH HOH A . BA 10 HOH 52 585 585 HOH HOH A . BA 10 HOH 53 586 586 HOH HOH A . BA 10 HOH 54 587 587 HOH HOH A . BA 10 HOH 55 588 588 HOH HOH A . BA 10 HOH 56 589 589 HOH HOH A . BA 10 HOH 57 590 590 HOH HOH A . BA 10 HOH 58 591 591 HOH HOH A . BA 10 HOH 59 592 592 HOH HOH A . BA 10 HOH 60 593 593 HOH HOH A . BA 10 HOH 61 594 594 HOH HOH A . BA 10 HOH 62 595 595 HOH HOH A . BA 10 HOH 63 596 596 HOH HOH A . BA 10 HOH 64 597 597 HOH HOH A . BA 10 HOH 65 598 598 HOH HOH A . BA 10 HOH 66 599 599 HOH HOH A . BA 10 HOH 67 600 600 HOH HOH A . BA 10 HOH 68 601 601 HOH HOH A . BA 10 HOH 69 602 602 HOH HOH A . BA 10 HOH 70 603 603 HOH HOH A . BA 10 HOH 71 604 604 HOH HOH A . BA 10 HOH 72 605 605 HOH HOH A . BA 10 HOH 73 606 606 HOH HOH A . BA 10 HOH 74 607 607 HOH HOH A . BA 10 HOH 75 608 608 HOH HOH A . BA 10 HOH 76 609 609 HOH HOH A . BA 10 HOH 77 610 610 HOH HOH A . BA 10 HOH 78 611 611 HOH HOH A . BA 10 HOH 79 612 612 HOH HOH A . BA 10 HOH 80 613 613 HOH HOH A . BA 10 HOH 81 614 614 HOH HOH A . BA 10 HOH 82 615 615 HOH HOH A . BA 10 HOH 83 616 616 HOH HOH A . BA 10 HOH 84 617 617 HOH HOH A . BA 10 HOH 85 618 618 HOH HOH A . BA 10 HOH 86 619 619 HOH HOH A . BA 10 HOH 87 620 620 HOH HOH A . BA 10 HOH 88 621 621 HOH HOH A . BA 10 HOH 89 622 622 HOH HOH A . BA 10 HOH 90 623 623 HOH HOH A . BA 10 HOH 91 624 624 HOH HOH A . BA 10 HOH 92 625 625 HOH HOH A . BA 10 HOH 93 626 626 HOH HOH A . BA 10 HOH 94 627 627 HOH HOH A . BA 10 HOH 95 628 628 HOH HOH A . BA 10 HOH 96 629 629 HOH HOH A . BA 10 HOH 97 630 630 HOH HOH A . BA 10 HOH 98 631 631 HOH HOH A . BA 10 HOH 99 632 632 HOH HOH A . BA 10 HOH 100 633 633 HOH HOH A . BA 10 HOH 101 634 634 HOH HOH A . BA 10 HOH 102 635 635 HOH HOH A . BA 10 HOH 103 636 636 HOH HOH A . BA 10 HOH 104 637 637 HOH HOH A . BA 10 HOH 105 638 638 HOH HOH A . BA 10 HOH 106 639 639 HOH HOH A . BA 10 HOH 107 640 640 HOH HOH A . BA 10 HOH 108 641 641 HOH HOH A . BA 10 HOH 109 642 642 HOH HOH A . BA 10 HOH 110 643 643 HOH HOH A . BA 10 HOH 111 644 644 HOH HOH A . BA 10 HOH 112 645 645 HOH HOH A . BA 10 HOH 113 646 646 HOH HOH A . BA 10 HOH 114 647 647 HOH HOH A . BA 10 HOH 115 648 648 HOH HOH A . BA 10 HOH 116 649 649 HOH HOH A . BA 10 HOH 117 650 650 HOH HOH A . BA 10 HOH 118 651 651 HOH HOH A . BA 10 HOH 119 652 652 HOH HOH A . BA 10 HOH 120 653 653 HOH HOH A . BA 10 HOH 121 654 654 HOH HOH A . BA 10 HOH 122 655 655 HOH HOH A . BA 10 HOH 123 656 656 HOH HOH A . BA 10 HOH 124 657 657 HOH HOH A . BA 10 HOH 125 658 658 HOH HOH A . BA 10 HOH 126 659 659 HOH HOH A . BA 10 HOH 127 660 660 HOH HOH A . BA 10 HOH 128 661 661 HOH HOH A . BA 10 HOH 129 662 662 HOH HOH A . BA 10 HOH 130 663 663 HOH HOH A . BA 10 HOH 131 664 664 HOH HOH A . BA 10 HOH 132 665 665 HOH HOH A . BA 10 HOH 133 666 666 HOH HOH A . BA 10 HOH 134 667 667 HOH HOH A . BA 10 HOH 135 668 668 HOH HOH A . BA 10 HOH 136 669 669 HOH HOH A . BA 10 HOH 137 670 670 HOH HOH A . BA 10 HOH 138 671 671 HOH HOH A . BA 10 HOH 139 672 672 HOH HOH A . BA 10 HOH 140 673 673 HOH HOH A . BA 10 HOH 141 674 674 HOH HOH A . BA 10 HOH 142 675 675 HOH HOH A . BA 10 HOH 143 676 676 HOH HOH A . BA 10 HOH 144 677 677 HOH HOH A . BA 10 HOH 145 678 678 HOH HOH A . BA 10 HOH 146 679 679 HOH HOH A . BA 10 HOH 147 680 680 HOH HOH A . BA 10 HOH 148 681 681 HOH HOH A . BA 10 HOH 149 682 682 HOH HOH A . BA 10 HOH 150 683 683 HOH HOH A . BA 10 HOH 151 684 684 HOH HOH A . BA 10 HOH 152 685 685 HOH HOH A . BA 10 HOH 153 686 686 HOH HOH A . BA 10 HOH 154 687 687 HOH HOH A . BA 10 HOH 155 688 688 HOH HOH A . BA 10 HOH 156 689 689 HOH HOH A . BA 10 HOH 157 690 690 HOH HOH A . BA 10 HOH 158 691 691 HOH HOH A . BA 10 HOH 159 692 692 HOH HOH A . BA 10 HOH 160 693 693 HOH HOH A . BA 10 HOH 161 694 694 HOH HOH A . BA 10 HOH 162 695 695 HOH HOH A . BA 10 HOH 163 696 696 HOH HOH A . BA 10 HOH 164 697 697 HOH HOH A . BA 10 HOH 165 698 698 HOH HOH A . BA 10 HOH 166 699 699 HOH HOH A . BA 10 HOH 167 700 700 HOH HOH A . BA 10 HOH 168 701 701 HOH HOH A . BA 10 HOH 169 702 702 HOH HOH A . BA 10 HOH 170 703 703 HOH HOH A . BA 10 HOH 171 704 704 HOH HOH A . BA 10 HOH 172 705 705 HOH HOH A . BA 10 HOH 173 706 706 HOH HOH A . BA 10 HOH 174 707 707 HOH HOH A . BA 10 HOH 175 708 708 HOH HOH A . BA 10 HOH 176 709 709 HOH HOH A . BA 10 HOH 177 710 710 HOH HOH A . BA 10 HOH 178 711 711 HOH HOH A . BA 10 HOH 179 712 712 HOH HOH A . BA 10 HOH 180 713 713 HOH HOH A . BA 10 HOH 181 714 714 HOH HOH A . BA 10 HOH 182 715 715 HOH HOH A . BA 10 HOH 183 716 716 HOH HOH A . BA 10 HOH 184 717 717 HOH HOH A . BA 10 HOH 185 718 718 HOH HOH A . BA 10 HOH 186 719 719 HOH HOH A . BA 10 HOH 187 720 720 HOH HOH A . BA 10 HOH 188 721 721 HOH HOH A . BA 10 HOH 189 722 722 HOH HOH A . BA 10 HOH 190 723 723 HOH HOH A . BA 10 HOH 191 724 724 HOH HOH A . BA 10 HOH 192 725 725 HOH HOH A . BA 10 HOH 193 726 726 HOH HOH A . BA 10 HOH 194 727 727 HOH HOH A . BA 10 HOH 195 728 728 HOH HOH A . BA 10 HOH 196 729 729 HOH HOH A . BA 10 HOH 197 730 730 HOH HOH A . BA 10 HOH 198 731 731 HOH HOH A . BA 10 HOH 199 732 732 HOH HOH A . BA 10 HOH 200 733 733 HOH HOH A . BA 10 HOH 201 734 734 HOH HOH A . BA 10 HOH 202 735 735 HOH HOH A . BA 10 HOH 203 736 736 HOH HOH A . BA 10 HOH 204 737 737 HOH HOH A . BA 10 HOH 205 738 738 HOH HOH A . BA 10 HOH 206 739 739 HOH HOH A . BA 10 HOH 207 740 740 HOH HOH A . BA 10 HOH 208 741 741 HOH HOH A . BA 10 HOH 209 742 742 HOH HOH A . BA 10 HOH 210 743 743 HOH HOH A . BA 10 HOH 211 744 744 HOH HOH A . BA 10 HOH 212 745 745 HOH HOH A . BA 10 HOH 213 746 746 HOH HOH A . BA 10 HOH 214 747 747 HOH HOH A . BA 10 HOH 215 748 748 HOH HOH A . BA 10 HOH 216 749 749 HOH HOH A . BA 10 HOH 217 750 750 HOH HOH A . BA 10 HOH 218 751 751 HOH HOH A . BA 10 HOH 219 752 752 HOH HOH A . BA 10 HOH 220 753 753 HOH HOH A . BA 10 HOH 221 754 754 HOH HOH A . BA 10 HOH 222 755 755 HOH HOH A . BA 10 HOH 223 756 756 HOH HOH A . BA 10 HOH 224 757 757 HOH HOH A . BA 10 HOH 225 758 758 HOH HOH A . BA 10 HOH 226 759 759 HOH HOH A . BA 10 HOH 227 760 760 HOH HOH A . BA 10 HOH 228 761 761 HOH HOH A . BA 10 HOH 229 762 762 HOH HOH A . BA 10 HOH 230 763 763 HOH HOH A . BA 10 HOH 231 764 764 HOH HOH A . BA 10 HOH 232 765 765 HOH HOH A . BA 10 HOH 233 766 766 HOH HOH A . BA 10 HOH 234 767 767 HOH HOH A . BA 10 HOH 235 768 768 HOH HOH A . BA 10 HOH 236 769 769 HOH HOH A . BA 10 HOH 237 770 770 HOH HOH A . BA 10 HOH 238 771 771 HOH HOH A . BA 10 HOH 239 772 772 HOH HOH A . BA 10 HOH 240 773 773 HOH HOH A . BA 10 HOH 241 774 774 HOH HOH A . BA 10 HOH 242 775 775 HOH HOH A . BA 10 HOH 243 776 776 HOH HOH A . BA 10 HOH 244 777 777 HOH HOH A . BA 10 HOH 245 778 778 HOH HOH A . BA 10 HOH 246 779 779 HOH HOH A . BA 10 HOH 247 780 780 HOH HOH A . BA 10 HOH 248 781 781 HOH HOH A . BA 10 HOH 249 782 782 HOH HOH A . BA 10 HOH 250 783 783 HOH HOH A . BA 10 HOH 251 784 784 HOH HOH A . BA 10 HOH 252 785 785 HOH HOH A . BA 10 HOH 253 786 786 HOH HOH A . BA 10 HOH 254 787 787 HOH HOH A . BA 10 HOH 255 788 788 HOH HOH A . BA 10 HOH 256 789 789 HOH HOH A . BA 10 HOH 257 790 790 HOH HOH A . BA 10 HOH 258 791 791 HOH HOH A . BA 10 HOH 259 792 792 HOH HOH A . BA 10 HOH 260 793 793 HOH HOH A . BA 10 HOH 261 794 794 HOH HOH A . BA 10 HOH 262 795 795 HOH HOH A . BA 10 HOH 263 796 796 HOH HOH A . BA 10 HOH 264 797 797 HOH HOH A . BA 10 HOH 265 798 798 HOH HOH A . BA 10 HOH 266 799 799 HOH HOH A . BA 10 HOH 267 800 800 HOH HOH A . BA 10 HOH 268 801 801 HOH HOH A . BA 10 HOH 269 802 802 HOH HOH A . BA 10 HOH 270 803 803 HOH HOH A . BA 10 HOH 271 804 804 HOH HOH A . BA 10 HOH 272 805 805 HOH HOH A . BA 10 HOH 273 806 806 HOH HOH A . BA 10 HOH 274 807 807 HOH HOH A . BA 10 HOH 275 808 808 HOH HOH A . BA 10 HOH 276 809 809 HOH HOH A . BA 10 HOH 277 810 810 HOH HOH A . BA 10 HOH 278 811 811 HOH HOH A . BA 10 HOH 279 812 812 HOH HOH A . BA 10 HOH 280 813 813 HOH HOH A . BA 10 HOH 281 814 814 HOH HOH A . BA 10 HOH 282 815 815 HOH HOH A . BA 10 HOH 283 816 816 HOH HOH A . BA 10 HOH 284 817 817 HOH HOH A . BA 10 HOH 285 818 818 HOH HOH A . BA 10 HOH 286 819 819 HOH HOH A . BA 10 HOH 287 820 820 HOH HOH A . BA 10 HOH 288 821 821 HOH HOH A . BA 10 HOH 289 822 822 HOH HOH A . BA 10 HOH 290 823 823 HOH HOH A . BA 10 HOH 291 824 824 HOH HOH A . BA 10 HOH 292 825 825 HOH HOH A . BA 10 HOH 293 826 826 HOH HOH A . BA 10 HOH 294 827 827 HOH HOH A . BA 10 HOH 295 828 828 HOH HOH A . BA 10 HOH 296 829 829 HOH HOH A . BA 10 HOH 297 830 830 HOH HOH A . BA 10 HOH 298 831 831 HOH HOH A . BA 10 HOH 299 832 832 HOH HOH A . BA 10 HOH 300 833 833 HOH HOH A . BA 10 HOH 301 834 834 HOH HOH A . BA 10 HOH 302 835 835 HOH HOH A . BA 10 HOH 303 836 836 HOH HOH A . BA 10 HOH 304 837 837 HOH HOH A . BA 10 HOH 305 838 838 HOH HOH A . BA 10 HOH 306 839 839 HOH HOH A . BA 10 HOH 307 840 840 HOH HOH A . BA 10 HOH 308 841 841 HOH HOH A . BA 10 HOH 309 842 842 HOH HOH A . BA 10 HOH 310 843 843 HOH HOH A . BA 10 HOH 311 844 844 HOH HOH A . BA 10 HOH 312 845 845 HOH HOH A . BA 10 HOH 313 846 846 HOH HOH A . BA 10 HOH 314 847 847 HOH HOH A . BA 10 HOH 315 848 848 HOH HOH A . BA 10 HOH 316 849 849 HOH HOH A . BA 10 HOH 317 850 850 HOH HOH A . BA 10 HOH 318 851 851 HOH HOH A . BA 10 HOH 319 852 852 HOH HOH A . BA 10 HOH 320 853 853 HOH HOH A . BA 10 HOH 321 854 854 HOH HOH A . BA 10 HOH 322 855 855 HOH HOH A . BA 10 HOH 323 856 856 HOH HOH A . BA 10 HOH 324 857 857 HOH HOH A . BA 10 HOH 325 858 858 HOH HOH A . BA 10 HOH 326 859 859 HOH HOH A . BA 10 HOH 327 860 860 HOH HOH A . BA 10 HOH 328 861 861 HOH HOH A . BA 10 HOH 329 862 862 HOH HOH A . BA 10 HOH 330 863 863 HOH HOH A . BA 10 HOH 331 864 864 HOH HOH A . BA 10 HOH 332 865 865 HOH HOH A . BA 10 HOH 333 866 866 HOH HOH A . BA 10 HOH 334 867 867 HOH HOH A . BA 10 HOH 335 868 868 HOH HOH A . BA 10 HOH 336 869 869 HOH HOH A . BA 10 HOH 337 870 870 HOH HOH A . BA 10 HOH 338 871 871 HOH HOH A . BA 10 HOH 339 872 872 HOH HOH A . BA 10 HOH 340 873 873 HOH HOH A . BA 10 HOH 341 874 874 HOH HOH A . BA 10 HOH 342 875 875 HOH HOH A . BA 10 HOH 343 876 876 HOH HOH A . BA 10 HOH 344 877 877 HOH HOH A . BA 10 HOH 345 878 878 HOH HOH A . BA 10 HOH 346 879 879 HOH HOH A . BA 10 HOH 347 880 880 HOH HOH A . BA 10 HOH 348 881 881 HOH HOH A . BA 10 HOH 349 882 882 HOH HOH A . BA 10 HOH 350 883 883 HOH HOH A . BA 10 HOH 351 884 884 HOH HOH A . BA 10 HOH 352 885 885 HOH HOH A . BA 10 HOH 353 886 886 HOH HOH A . BA 10 HOH 354 887 887 HOH HOH A . BA 10 HOH 355 888 888 HOH HOH A . BA 10 HOH 356 889 889 HOH HOH A . BA 10 HOH 357 890 890 HOH HOH A . BA 10 HOH 358 891 891 HOH HOH A . BA 10 HOH 359 892 892 HOH HOH A . BA 10 HOH 360 893 893 HOH HOH A . BA 10 HOH 361 894 894 HOH HOH A . BA 10 HOH 362 895 895 HOH HOH A . BA 10 HOH 363 896 896 HOH HOH A . BA 10 HOH 364 897 897 HOH HOH A . BA 10 HOH 365 898 898 HOH HOH A . BA 10 HOH 366 899 899 HOH HOH A . BA 10 HOH 367 900 900 HOH HOH A . BA 10 HOH 368 901 901 HOH HOH A . BA 10 HOH 369 902 902 HOH HOH A . BA 10 HOH 370 903 903 HOH HOH A . BA 10 HOH 371 904 904 HOH HOH A . BA 10 HOH 372 905 905 HOH HOH A . BA 10 HOH 373 906 906 HOH HOH A . BA 10 HOH 374 907 907 HOH HOH A . BA 10 HOH 375 908 908 HOH HOH A . BA 10 HOH 376 909 909 HOH HOH A . BA 10 HOH 377 910 910 HOH HOH A . BA 10 HOH 378 911 911 HOH HOH A . BA 10 HOH 379 912 912 HOH HOH A . BA 10 HOH 380 913 913 HOH HOH A . BA 10 HOH 381 914 914 HOH HOH A . BA 10 HOH 382 915 915 HOH HOH A . BA 10 HOH 383 916 916 HOH HOH A . BA 10 HOH 384 917 917 HOH HOH A . BA 10 HOH 385 918 918 HOH HOH A . BA 10 HOH 386 919 919 HOH HOH A . BA 10 HOH 387 920 920 HOH HOH A . BA 10 HOH 388 921 921 HOH HOH A . BA 10 HOH 389 922 922 HOH HOH A . BA 10 HOH 390 923 923 HOH HOH A . BA 10 HOH 391 924 924 HOH HOH A . BA 10 HOH 392 925 925 HOH HOH A . BA 10 HOH 393 926 926 HOH HOH A . BA 10 HOH 394 927 927 HOH HOH A . BA 10 HOH 395 928 928 HOH HOH A . BA 10 HOH 396 929 929 HOH HOH A . BA 10 HOH 397 930 930 HOH HOH A . BA 10 HOH 398 931 931 HOH HOH A . BA 10 HOH 399 932 932 HOH HOH A . BA 10 HOH 400 933 933 HOH HOH A . BA 10 HOH 401 934 934 HOH HOH A . BA 10 HOH 402 935 935 HOH HOH A . BA 10 HOH 403 936 936 HOH HOH A . BA 10 HOH 404 937 937 HOH HOH A . BA 10 HOH 405 938 938 HOH HOH A . BA 10 HOH 406 939 939 HOH HOH A . BA 10 HOH 407 940 940 HOH HOH A . BA 10 HOH 408 941 941 HOH HOH A . BA 10 HOH 409 942 942 HOH HOH A . BA 10 HOH 410 943 943 HOH HOH A . BA 10 HOH 411 944 944 HOH HOH A . BA 10 HOH 412 945 945 HOH HOH A . BA 10 HOH 413 946 946 HOH HOH A . BA 10 HOH 414 947 947 HOH HOH A . BA 10 HOH 415 948 948 HOH HOH A . BA 10 HOH 416 949 949 HOH HOH A . BA 10 HOH 417 950 950 HOH HOH A . BA 10 HOH 418 951 951 HOH HOH A . BA 10 HOH 419 952 952 HOH HOH A . BA 10 HOH 420 953 953 HOH HOH A . BA 10 HOH 421 954 954 HOH HOH A . BA 10 HOH 422 955 955 HOH HOH A . BA 10 HOH 423 956 956 HOH HOH A . BA 10 HOH 424 957 957 HOH HOH A . BA 10 HOH 425 958 958 HOH HOH A . BA 10 HOH 426 959 959 HOH HOH A . BA 10 HOH 427 960 960 HOH HOH A . BA 10 HOH 428 961 961 HOH HOH A . BA 10 HOH 429 962 962 HOH HOH A . BA 10 HOH 430 963 963 HOH HOH A . BA 10 HOH 431 964 964 HOH HOH A . BA 10 HOH 432 965 965 HOH HOH A . BA 10 HOH 433 966 966 HOH HOH A . BA 10 HOH 434 967 967 HOH HOH A . BA 10 HOH 435 968 968 HOH HOH A . BA 10 HOH 436 969 969 HOH HOH A . BA 10 HOH 437 970 970 HOH HOH A . BA 10 HOH 438 971 971 HOH HOH A . BA 10 HOH 439 972 972 HOH HOH A . BA 10 HOH 440 973 973 HOH HOH A . BA 10 HOH 441 974 974 HOH HOH A . BA 10 HOH 442 975 975 HOH HOH A . BA 10 HOH 443 976 976 HOH HOH A . BA 10 HOH 444 977 977 HOH HOH A . BA 10 HOH 445 978 978 HOH HOH A . BA 10 HOH 446 979 979 HOH HOH A . BA 10 HOH 447 980 980 HOH HOH A . BA 10 HOH 448 981 981 HOH HOH A . BA 10 HOH 449 982 982 HOH HOH A . BA 10 HOH 450 983 983 HOH HOH A . BA 10 HOH 451 984 984 HOH HOH A . BA 10 HOH 452 985 985 HOH HOH A . BA 10 HOH 453 986 986 HOH HOH A . BA 10 HOH 454 987 987 HOH HOH A . BA 10 HOH 455 988 988 HOH HOH A . BA 10 HOH 456 989 989 HOH HOH A . BA 10 HOH 457 990 990 HOH HOH A . BA 10 HOH 458 991 991 HOH HOH A . BA 10 HOH 459 992 992 HOH HOH A . BA 10 HOH 460 993 993 HOH HOH A . BA 10 HOH 461 994 994 HOH HOH A . BA 10 HOH 462 995 995 HOH HOH A . BA 10 HOH 463 996 996 HOH HOH A . BA 10 HOH 464 997 997 HOH HOH A . BA 10 HOH 465 998 998 HOH HOH A . BA 10 HOH 466 999 999 HOH HOH A . BA 10 HOH 467 1000 1000 HOH HOH A . BA 10 HOH 468 1001 1001 HOH HOH A . BA 10 HOH 469 1002 1002 HOH HOH A . BA 10 HOH 470 1003 1003 HOH HOH A . BA 10 HOH 471 1004 1004 HOH HOH A . BA 10 HOH 472 1005 1005 HOH HOH A . BA 10 HOH 473 1006 1006 HOH HOH A . BA 10 HOH 474 1007 1007 HOH HOH A . BA 10 HOH 475 1008 1008 HOH HOH A . BA 10 HOH 476 1009 1009 HOH HOH A . BA 10 HOH 477 1010 1010 HOH HOH A . BA 10 HOH 478 1011 1011 HOH HOH A . BA 10 HOH 479 1012 1012 HOH HOH A . BA 10 HOH 480 1013 1013 HOH HOH A . BA 10 HOH 481 1014 1014 HOH HOH A . BA 10 HOH 482 1015 1015 HOH HOH A . BA 10 HOH 483 1016 1016 HOH HOH A . BA 10 HOH 484 1017 1017 HOH HOH A . BA 10 HOH 485 1018 1018 HOH HOH A . BA 10 HOH 486 1019 1019 HOH HOH A . BA 10 HOH 487 1020 1020 HOH HOH A . BA 10 HOH 488 1021 1021 HOH HOH A . BA 10 HOH 489 1022 1022 HOH HOH A . BA 10 HOH 490 1023 1023 HOH HOH A . BA 10 HOH 491 1024 1024 HOH HOH A . BA 10 HOH 492 1025 1025 HOH HOH A . BA 10 HOH 493 1026 1026 HOH HOH A . BA 10 HOH 494 1027 1027 HOH HOH A . BA 10 HOH 495 1028 1028 HOH HOH A . BA 10 HOH 496 1029 1029 HOH HOH A . BA 10 HOH 497 1030 1030 HOH HOH A . BA 10 HOH 498 1031 1031 HOH HOH A . BA 10 HOH 499 1032 1032 HOH HOH A . BA 10 HOH 500 1033 1033 HOH HOH A . BA 10 HOH 501 1034 1034 HOH HOH A . BA 10 HOH 502 1035 1035 HOH HOH A . BA 10 HOH 503 1036 1036 HOH HOH A . BA 10 HOH 504 1037 1037 HOH HOH A . BA 10 HOH 505 1038 1038 HOH HOH A . BA 10 HOH 506 1039 1039 HOH HOH A . BA 10 HOH 507 1040 1040 HOH HOH A . BA 10 HOH 508 1041 1041 HOH HOH A . BA 10 HOH 509 1042 1042 HOH HOH A . BA 10 HOH 510 1043 1043 HOH HOH A . BA 10 HOH 511 1044 1044 HOH HOH A . BA 10 HOH 512 1045 1045 HOH HOH A . BA 10 HOH 513 1046 1046 HOH HOH A . BA 10 HOH 514 1047 1047 HOH HOH A . BA 10 HOH 515 1048 1048 HOH HOH A . BA 10 HOH 516 1049 1049 HOH HOH A . BA 10 HOH 517 1050 1050 HOH HOH A . BA 10 HOH 518 1051 1051 HOH HOH A . BA 10 HOH 519 1052 1052 HOH HOH A . BA 10 HOH 520 1053 1053 HOH HOH A . BA 10 HOH 521 1054 1054 HOH HOH A . BA 10 HOH 522 1055 1055 HOH HOH A . BA 10 HOH 523 1056 1056 HOH HOH A . BA 10 HOH 524 1057 1057 HOH HOH A . BA 10 HOH 525 1058 1058 HOH HOH A . BA 10 HOH 526 1059 1059 HOH HOH A . BA 10 HOH 527 1060 1060 HOH HOH A . BA 10 HOH 528 1061 1061 HOH HOH A . BA 10 HOH 529 1062 1062 HOH HOH A . BA 10 HOH 530 1063 1063 HOH HOH A . BA 10 HOH 531 1064 1064 HOH HOH A . BA 10 HOH 532 1065 1065 HOH HOH A . BA 10 HOH 533 1066 1066 HOH HOH A . BA 10 HOH 534 1067 1067 HOH HOH A . BA 10 HOH 535 1068 1068 HOH HOH A . BA 10 HOH 536 1069 1069 HOH HOH A . BA 10 HOH 537 1070 1070 HOH HOH A . BA 10 HOH 538 1071 1071 HOH HOH A . BA 10 HOH 539 1072 1072 HOH HOH A . BA 10 HOH 540 1073 1073 HOH HOH A . BA 10 HOH 541 1074 1074 HOH HOH A . BA 10 HOH 542 1075 1075 HOH HOH A . BA 10 HOH 543 1076 1076 HOH HOH A . BA 10 HOH 544 1077 1077 HOH HOH A . BA 10 HOH 545 1078 1078 HOH HOH A . BA 10 HOH 546 1079 1079 HOH HOH A . BA 10 HOH 547 1080 1080 HOH HOH A . BA 10 HOH 548 1081 1081 HOH HOH A . BA 10 HOH 549 1082 1082 HOH HOH A . BA 10 HOH 550 1083 1083 HOH HOH A . BA 10 HOH 551 1084 1084 HOH HOH A . BA 10 HOH 552 1085 1085 HOH HOH A . BA 10 HOH 553 1086 1086 HOH HOH A . BA 10 HOH 554 1087 1087 HOH HOH A . BA 10 HOH 555 1088 1088 HOH HOH A . BA 10 HOH 556 1089 1089 HOH HOH A . BA 10 HOH 557 1090 1090 HOH HOH A . BA 10 HOH 558 1091 1091 HOH HOH A . BA 10 HOH 559 1092 1092 HOH HOH A . BA 10 HOH 560 1093 1093 HOH HOH A . BA 10 HOH 561 1094 1094 HOH HOH A . BA 10 HOH 562 1095 1095 HOH HOH A . BA 10 HOH 563 1096 1096 HOH HOH A . BA 10 HOH 564 1097 1097 HOH HOH A . BA 10 HOH 565 1098 1098 HOH HOH A . BA 10 HOH 566 1099 1099 HOH HOH A . BA 10 HOH 567 1100 1100 HOH HOH A . BA 10 HOH 568 1101 1101 HOH HOH A . BA 10 HOH 569 1102 1102 HOH HOH A . BA 10 HOH 570 1103 1103 HOH HOH A . BA 10 HOH 571 1104 1104 HOH HOH A . BA 10 HOH 572 1105 1105 HOH HOH A . BA 10 HOH 573 1106 1106 HOH HOH A . BA 10 HOH 574 1107 1107 HOH HOH A . BA 10 HOH 575 1108 1108 HOH HOH A . BA 10 HOH 576 1109 1109 HOH HOH A . BA 10 HOH 577 1110 1110 HOH HOH A . BA 10 HOH 578 1111 1111 HOH HOH A . BA 10 HOH 579 1112 1112 HOH HOH A . BA 10 HOH 580 1113 1113 HOH HOH A . BA 10 HOH 581 1114 1114 HOH HOH A . BA 10 HOH 582 1115 1115 HOH HOH A . BA 10 HOH 583 1116 1116 HOH HOH A . BA 10 HOH 584 1117 1117 HOH HOH A . BA 10 HOH 585 1118 1118 HOH HOH A . BA 10 HOH 586 1119 1119 HOH HOH A . BA 10 HOH 587 1120 1120 HOH HOH A . BA 10 HOH 588 1121 1121 HOH HOH A . BA 10 HOH 589 1122 1122 HOH HOH A . BA 10 HOH 590 1123 1123 HOH HOH A . BA 10 HOH 591 1124 1124 HOH HOH A . BA 10 HOH 592 1125 1125 HOH HOH A . BA 10 HOH 593 1126 1126 HOH HOH A . BA 10 HOH 594 1127 1127 HOH HOH A . BA 10 HOH 595 1128 1128 HOH HOH A . BA 10 HOH 596 1129 1129 HOH HOH A . BA 10 HOH 597 1130 1130 HOH HOH A . BA 10 HOH 598 1131 1131 HOH HOH A . BA 10 HOH 599 1132 1132 HOH HOH A . BA 10 HOH 600 1133 1133 HOH HOH A . BA 10 HOH 601 1134 1134 HOH HOH A . BA 10 HOH 602 1135 1135 HOH HOH A . BA 10 HOH 603 1136 1136 HOH HOH A . BA 10 HOH 604 1137 1137 HOH HOH A . BA 10 HOH 605 1138 1138 HOH HOH A . BA 10 HOH 606 1139 1139 HOH HOH A . BA 10 HOH 607 1140 1140 HOH HOH A . BA 10 HOH 608 1141 1141 HOH HOH A . BA 10 HOH 609 1142 1142 HOH HOH A . BA 10 HOH 610 1143 1143 HOH HOH A . BA 10 HOH 611 1144 1144 HOH HOH A . BA 10 HOH 612 1145 1145 HOH HOH A . BA 10 HOH 613 1146 1146 HOH HOH A . BA 10 HOH 614 1147 1147 HOH HOH A . BA 10 HOH 615 1148 1148 HOH HOH A . BA 10 HOH 616 1149 1149 HOH HOH A . BA 10 HOH 617 1150 1150 HOH HOH A . BA 10 HOH 618 1151 1151 HOH HOH A . BA 10 HOH 619 1152 1152 HOH HOH A . BA 10 HOH 620 1153 1153 HOH HOH A . BA 10 HOH 621 1154 1154 HOH HOH A . BA 10 HOH 622 1155 1155 HOH HOH A . BA 10 HOH 623 1156 1156 HOH HOH A . BA 10 HOH 624 1157 1157 HOH HOH A . BA 10 HOH 625 1158 1158 HOH HOH A . BA 10 HOH 626 1159 1159 HOH HOH A . BA 10 HOH 627 1160 1160 HOH HOH A . BA 10 HOH 628 1161 1161 HOH HOH A . BA 10 HOH 629 1162 1162 HOH HOH A . BA 10 HOH 630 1163 1163 HOH HOH A . BA 10 HOH 631 1164 1164 HOH HOH A . BA 10 HOH 632 1165 1165 HOH HOH A . BA 10 HOH 633 1166 1166 HOH HOH A . BA 10 HOH 634 1167 1167 HOH HOH A . BA 10 HOH 635 1168 1168 HOH HOH A . BA 10 HOH 636 1169 1169 HOH HOH A . BA 10 HOH 637 1170 1170 HOH HOH A . BA 10 HOH 638 1171 1171 HOH HOH A . BA 10 HOH 639 1172 1172 HOH HOH A . BA 10 HOH 640 1173 1173 HOH HOH A . BA 10 HOH 641 1174 1174 HOH HOH A . BA 10 HOH 642 1175 1175 HOH HOH A . BA 10 HOH 643 1176 1176 HOH HOH A . BA 10 HOH 644 1177 1177 HOH HOH A . BA 10 HOH 645 1178 1178 HOH HOH A . BA 10 HOH 646 1179 1179 HOH HOH A . BA 10 HOH 647 1180 1180 HOH HOH A . BA 10 HOH 648 1181 1181 HOH HOH A . BA 10 HOH 649 1182 1182 HOH HOH A . BA 10 HOH 650 1183 1183 HOH HOH A . BA 10 HOH 651 1184 1184 HOH HOH A . BA 10 HOH 652 1185 1185 HOH HOH A . BA 10 HOH 653 1186 1186 HOH HOH A . BA 10 HOH 654 1187 1187 HOH HOH A . BA 10 HOH 655 1188 1188 HOH HOH A . BA 10 HOH 656 1189 1189 HOH HOH A . BA 10 HOH 657 1190 1190 HOH HOH A . BA 10 HOH 658 1191 1191 HOH HOH A . BA 10 HOH 659 1192 1192 HOH HOH A . BA 10 HOH 660 1193 1193 HOH HOH A . BA 10 HOH 661 1194 1194 HOH HOH A . BA 10 HOH 662 1195 1195 HOH HOH A . BA 10 HOH 663 1196 1196 HOH HOH A . BA 10 HOH 664 1197 1197 HOH HOH A . BA 10 HOH 665 1198 1198 HOH HOH A . BA 10 HOH 666 1199 1199 HOH HOH A . BA 10 HOH 667 1200 1200 HOH HOH A . BA 10 HOH 668 1201 1201 HOH HOH A . BA 10 HOH 669 1202 1202 HOH HOH A . BA 10 HOH 670 1203 1203 HOH HOH A . BA 10 HOH 671 1204 1204 HOH HOH A . BA 10 HOH 672 1205 1205 HOH HOH A . BA 10 HOH 673 1206 1206 HOH HOH A . BA 10 HOH 674 1207 1207 HOH HOH A . BA 10 HOH 675 1208 1208 HOH HOH A . BA 10 HOH 676 1209 1209 HOH HOH A . BA 10 HOH 677 1210 1210 HOH HOH A . BA 10 HOH 678 1211 1211 HOH HOH A . BA 10 HOH 679 1212 1212 HOH HOH A . BA 10 HOH 680 1213 1213 HOH HOH A . BA 10 HOH 681 1214 1214 HOH HOH A . BA 10 HOH 682 1215 1215 HOH HOH A . BA 10 HOH 683 1216 1216 HOH HOH A . BA 10 HOH 684 1217 1217 HOH HOH A . BA 10 HOH 685 1218 1218 HOH HOH A . BA 10 HOH 686 1219 1219 HOH HOH A . BA 10 HOH 687 1220 1220 HOH HOH A . BA 10 HOH 688 1221 1221 HOH HOH A . BA 10 HOH 689 1222 1222 HOH HOH A . BA 10 HOH 690 1223 1223 HOH HOH A . BA 10 HOH 691 1224 1224 HOH HOH A . BA 10 HOH 692 1225 1225 HOH HOH A . BA 10 HOH 693 1226 1226 HOH HOH A . BA 10 HOH 694 1227 1227 HOH HOH A . BA 10 HOH 695 1228 1228 HOH HOH A . BA 10 HOH 696 1229 1229 HOH HOH A . BA 10 HOH 697 1230 1230 HOH HOH A . BA 10 HOH 698 1231 1231 HOH HOH A . BA 10 HOH 699 1232 1232 HOH HOH A . BA 10 HOH 700 1233 1233 HOH HOH A . BA 10 HOH 701 1234 1234 HOH HOH A . BA 10 HOH 702 1235 1235 HOH HOH A . BA 10 HOH 703 1236 1236 HOH HOH A . BA 10 HOH 704 1237 1237 HOH HOH A . BA 10 HOH 705 1238 1238 HOH HOH A . BA 10 HOH 706 1239 1239 HOH HOH A . BA 10 HOH 707 1240 1240 HOH HOH A . BA 10 HOH 708 1241 1241 HOH HOH A . BA 10 HOH 709 1242 1242 HOH HOH A . BA 10 HOH 710 1243 1243 HOH HOH A . BA 10 HOH 711 1244 1244 HOH HOH A . BA 10 HOH 712 1245 1245 HOH HOH A . BA 10 HOH 713 1246 1246 HOH HOH A . BA 10 HOH 714 1247 1247 HOH HOH A . BA 10 HOH 715 1248 1248 HOH HOH A . BA 10 HOH 716 1249 1249 HOH HOH A . BA 10 HOH 717 1250 1250 HOH HOH A . BA 10 HOH 718 1251 1251 HOH HOH A . BA 10 HOH 719 1252 1252 HOH HOH A . BA 10 HOH 720 1253 1253 HOH HOH A . BA 10 HOH 721 1254 1254 HOH HOH A . BA 10 HOH 722 1255 1255 HOH HOH A . BA 10 HOH 723 1256 1256 HOH HOH A . BA 10 HOH 724 1257 1257 HOH HOH A . BA 10 HOH 725 1258 1258 HOH HOH A . BA 10 HOH 726 1259 1259 HOH HOH A . BA 10 HOH 727 1260 1260 HOH HOH A . BA 10 HOH 728 1261 1261 HOH HOH A . BA 10 HOH 729 1262 1262 HOH HOH A . BA 10 HOH 730 1263 1263 HOH HOH A . BA 10 HOH 731 1264 1264 HOH HOH A . BA 10 HOH 732 1265 1265 HOH HOH A . BA 10 HOH 733 1266 1266 HOH HOH A . BA 10 HOH 734 1267 1267 HOH HOH A . BA 10 HOH 735 1268 1268 HOH HOH A . BA 10 HOH 736 1269 1269 HOH HOH A . BA 10 HOH 737 1270 1270 HOH HOH A . BA 10 HOH 738 1271 1271 HOH HOH A . BA 10 HOH 739 1272 1272 HOH HOH A . BA 10 HOH 740 1273 1273 HOH HOH A . BA 10 HOH 741 1274 1274 HOH HOH A . BA 10 HOH 742 1275 1275 HOH HOH A . BA 10 HOH 743 1276 1276 HOH HOH A . BA 10 HOH 744 1277 1277 HOH HOH A . BA 10 HOH 745 1278 1278 HOH HOH A . BA 10 HOH 746 1279 1279 HOH HOH A . BA 10 HOH 747 1280 1280 HOH HOH A . BA 10 HOH 748 1281 1281 HOH HOH A . BA 10 HOH 749 1282 1282 HOH HOH A . BA 10 HOH 750 1283 1283 HOH HOH A . BA 10 HOH 751 1284 1284 HOH HOH A . BA 10 HOH 752 1285 1285 HOH HOH A . BA 10 HOH 753 1286 1286 HOH HOH A . BA 10 HOH 754 1287 1287 HOH HOH A . BA 10 HOH 755 1288 1288 HOH HOH A . BA 10 HOH 756 1289 1289 HOH HOH A . BA 10 HOH 757 1290 1290 HOH HOH A . BA 10 HOH 758 1291 1291 HOH HOH A . BA 10 HOH 759 1292 1292 HOH HOH A . BA 10 HOH 760 1293 1293 HOH HOH A . BA 10 HOH 761 1294 1294 HOH HOH A . BA 10 HOH 762 1295 1295 HOH HOH A . BA 10 HOH 763 1296 1296 HOH HOH A . BA 10 HOH 764 1297 1297 HOH HOH A . BA 10 HOH 765 1298 1298 HOH HOH A . BA 10 HOH 766 1299 1299 HOH HOH A . BA 10 HOH 767 1300 1300 HOH HOH A . BA 10 HOH 768 1301 1301 HOH HOH A . BA 10 HOH 769 1302 1302 HOH HOH A . BA 10 HOH 770 1303 1303 HOH HOH A . BA 10 HOH 771 1304 1304 HOH HOH A . BA 10 HOH 772 1305 1305 HOH HOH A . BA 10 HOH 773 1306 1306 HOH HOH A . BA 10 HOH 774 1307 1307 HOH HOH A . BA 10 HOH 775 1308 1308 HOH HOH A . BA 10 HOH 776 1309 1309 HOH HOH A . BA 10 HOH 777 1310 1310 HOH HOH A . BA 10 HOH 778 1311 1311 HOH HOH A . BA 10 HOH 779 1312 1312 HOH HOH A . BA 10 HOH 780 1313 1313 HOH HOH A . BA 10 HOH 781 1314 1314 HOH HOH A . BA 10 HOH 782 1315 1315 HOH HOH A . BA 10 HOH 783 1316 1316 HOH HOH A . BA 10 HOH 784 1317 1317 HOH HOH A . BA 10 HOH 785 1318 1318 HOH HOH A . BA 10 HOH 786 1319 1319 HOH HOH A . BA 10 HOH 787 1320 1320 HOH HOH A . BA 10 HOH 788 1321 1321 HOH HOH A . BA 10 HOH 789 1322 1322 HOH HOH A . BA 10 HOH 790 1323 1323 HOH HOH A . BA 10 HOH 791 1324 1324 HOH HOH A . BA 10 HOH 792 1325 1325 HOH HOH A . BA 10 HOH 793 1326 1326 HOH HOH A . BA 10 HOH 794 1327 1327 HOH HOH A . BA 10 HOH 795 1328 1328 HOH HOH A . BA 10 HOH 796 1329 1329 HOH HOH A . BA 10 HOH 797 1330 1330 HOH HOH A . BA 10 HOH 798 1331 1331 HOH HOH A . BA 10 HOH 799 1332 1332 HOH HOH A . BA 10 HOH 800 1333 1333 HOH HOH A . BA 10 HOH 801 1334 1334 HOH HOH A . BA 10 HOH 802 1335 1335 HOH HOH A . BA 10 HOH 803 1336 1336 HOH HOH A . BA 10 HOH 804 1337 1337 HOH HOH A . BA 10 HOH 805 1338 1338 HOH HOH A . BA 10 HOH 806 1339 1339 HOH HOH A . BA 10 HOH 807 1340 1340 HOH HOH A . BA 10 HOH 808 1341 1341 HOH HOH A . BA 10 HOH 809 1342 1342 HOH HOH A . BA 10 HOH 810 1343 1343 HOH HOH A . BA 10 HOH 811 1344 1344 HOH HOH A . BA 10 HOH 812 1345 1345 HOH HOH A . BA 10 HOH 813 1346 1346 HOH HOH A . BA 10 HOH 814 1347 1347 HOH HOH A . BA 10 HOH 815 1348 1348 HOH HOH A . BA 10 HOH 816 1349 1349 HOH HOH A . BA 10 HOH 817 1350 1350 HOH HOH A . BA 10 HOH 818 1351 1351 HOH HOH A . BA 10 HOH 819 1352 1352 HOH HOH A . BA 10 HOH 820 1353 1353 HOH HOH A . BA 10 HOH 821 1366 1366 HOH HOH A . BA 10 HOH 822 1504 1504 HOH HOH A . BA 10 HOH 823 1584 1584 HOH HOH A . CA 10 HOH 1 535 535 HOH HOH B . CA 10 HOH 2 590 590 HOH HOH B . CA 10 HOH 3 625 625 HOH HOH B . CA 10 HOH 4 826 826 HOH HOH B . CA 10 HOH 5 829 829 HOH HOH B . CA 10 HOH 6 830 830 HOH HOH B . CA 10 HOH 7 831 831 HOH HOH B . CA 10 HOH 8 832 832 HOH HOH B . CA 10 HOH 9 833 833 HOH HOH B . CA 10 HOH 10 834 834 HOH HOH B . CA 10 HOH 11 835 835 HOH HOH B . CA 10 HOH 12 836 836 HOH HOH B . CA 10 HOH 13 837 837 HOH HOH B . CA 10 HOH 14 838 838 HOH HOH B . CA 10 HOH 15 839 839 HOH HOH B . CA 10 HOH 16 840 840 HOH HOH B . CA 10 HOH 17 841 841 HOH HOH B . CA 10 HOH 18 842 842 HOH HOH B . CA 10 HOH 19 843 843 HOH HOH B . CA 10 HOH 20 844 844 HOH HOH B . CA 10 HOH 21 845 845 HOH HOH B . CA 10 HOH 22 846 846 HOH HOH B . CA 10 HOH 23 847 847 HOH HOH B . CA 10 HOH 24 848 848 HOH HOH B . CA 10 HOH 25 849 849 HOH HOH B . CA 10 HOH 26 850 850 HOH HOH B . CA 10 HOH 27 851 851 HOH HOH B . CA 10 HOH 28 852 852 HOH HOH B . CA 10 HOH 29 853 853 HOH HOH B . CA 10 HOH 30 854 854 HOH HOH B . CA 10 HOH 31 855 855 HOH HOH B . CA 10 HOH 32 856 856 HOH HOH B . CA 10 HOH 33 857 857 HOH HOH B . CA 10 HOH 34 858 858 HOH HOH B . CA 10 HOH 35 859 859 HOH HOH B . CA 10 HOH 36 860 860 HOH HOH B . CA 10 HOH 37 861 861 HOH HOH B . CA 10 HOH 38 862 862 HOH HOH B . CA 10 HOH 39 863 863 HOH HOH B . CA 10 HOH 40 864 864 HOH HOH B . CA 10 HOH 41 865 865 HOH HOH B . CA 10 HOH 42 866 866 HOH HOH B . CA 10 HOH 43 867 867 HOH HOH B . CA 10 HOH 44 868 868 HOH HOH B . CA 10 HOH 45 869 869 HOH HOH B . CA 10 HOH 46 870 870 HOH HOH B . CA 10 HOH 47 871 871 HOH HOH B . CA 10 HOH 48 872 872 HOH HOH B . CA 10 HOH 49 873 873 HOH HOH B . CA 10 HOH 50 874 874 HOH HOH B . CA 10 HOH 51 875 875 HOH HOH B . CA 10 HOH 52 876 876 HOH HOH B . CA 10 HOH 53 877 877 HOH HOH B . CA 10 HOH 54 878 878 HOH HOH B . CA 10 HOH 55 879 879 HOH HOH B . CA 10 HOH 56 880 880 HOH HOH B . CA 10 HOH 57 881 881 HOH HOH B . CA 10 HOH 58 882 882 HOH HOH B . CA 10 HOH 59 883 883 HOH HOH B . CA 10 HOH 60 884 884 HOH HOH B . CA 10 HOH 61 885 885 HOH HOH B . CA 10 HOH 62 886 886 HOH HOH B . CA 10 HOH 63 887 887 HOH HOH B . CA 10 HOH 64 888 888 HOH HOH B . CA 10 HOH 65 889 889 HOH HOH B . CA 10 HOH 66 890 890 HOH HOH B . CA 10 HOH 67 891 891 HOH HOH B . CA 10 HOH 68 892 892 HOH HOH B . CA 10 HOH 69 893 893 HOH HOH B . CA 10 HOH 70 894 894 HOH HOH B . CA 10 HOH 71 895 895 HOH HOH B . CA 10 HOH 72 896 896 HOH HOH B . CA 10 HOH 73 897 897 HOH HOH B . CA 10 HOH 74 898 898 HOH HOH B . CA 10 HOH 75 899 899 HOH HOH B . CA 10 HOH 76 900 900 HOH HOH B . CA 10 HOH 77 901 901 HOH HOH B . CA 10 HOH 78 902 902 HOH HOH B . CA 10 HOH 79 903 903 HOH HOH B . CA 10 HOH 80 904 904 HOH HOH B . CA 10 HOH 81 905 905 HOH HOH B . CA 10 HOH 82 906 906 HOH HOH B . CA 10 HOH 83 907 907 HOH HOH B . CA 10 HOH 84 908 908 HOH HOH B . CA 10 HOH 85 909 909 HOH HOH B . CA 10 HOH 86 910 910 HOH HOH B . CA 10 HOH 87 911 911 HOH HOH B . CA 10 HOH 88 912 912 HOH HOH B . CA 10 HOH 89 913 913 HOH HOH B . CA 10 HOH 90 914 914 HOH HOH B . CA 10 HOH 91 915 915 HOH HOH B . CA 10 HOH 92 916 916 HOH HOH B . CA 10 HOH 93 917 917 HOH HOH B . CA 10 HOH 94 918 918 HOH HOH B . CA 10 HOH 95 919 919 HOH HOH B . CA 10 HOH 96 920 920 HOH HOH B . CA 10 HOH 97 921 921 HOH HOH B . CA 10 HOH 98 922 922 HOH HOH B . CA 10 HOH 99 923 923 HOH HOH B . CA 10 HOH 100 924 924 HOH HOH B . CA 10 HOH 101 925 925 HOH HOH B . CA 10 HOH 102 926 926 HOH HOH B . CA 10 HOH 103 927 927 HOH HOH B . CA 10 HOH 104 928 928 HOH HOH B . CA 10 HOH 105 929 929 HOH HOH B . CA 10 HOH 106 930 930 HOH HOH B . CA 10 HOH 107 931 931 HOH HOH B . CA 10 HOH 108 932 932 HOH HOH B . CA 10 HOH 109 933 933 HOH HOH B . CA 10 HOH 110 934 934 HOH HOH B . CA 10 HOH 111 935 935 HOH HOH B . CA 10 HOH 112 936 936 HOH HOH B . CA 10 HOH 113 937 937 HOH HOH B . CA 10 HOH 114 938 938 HOH HOH B . CA 10 HOH 115 939 939 HOH HOH B . CA 10 HOH 116 940 940 HOH HOH B . CA 10 HOH 117 941 941 HOH HOH B . CA 10 HOH 118 942 942 HOH HOH B . CA 10 HOH 119 943 943 HOH HOH B . CA 10 HOH 120 944 944 HOH HOH B . CA 10 HOH 121 945 945 HOH HOH B . CA 10 HOH 122 946 946 HOH HOH B . CA 10 HOH 123 947 947 HOH HOH B . CA 10 HOH 124 948 948 HOH HOH B . CA 10 HOH 125 949 949 HOH HOH B . CA 10 HOH 126 950 950 HOH HOH B . CA 10 HOH 127 951 951 HOH HOH B . CA 10 HOH 128 952 952 HOH HOH B . CA 10 HOH 129 953 953 HOH HOH B . CA 10 HOH 130 954 954 HOH HOH B . CA 10 HOH 131 955 955 HOH HOH B . CA 10 HOH 132 956 956 HOH HOH B . CA 10 HOH 133 957 957 HOH HOH B . CA 10 HOH 134 958 958 HOH HOH B . CA 10 HOH 135 959 959 HOH HOH B . CA 10 HOH 136 960 960 HOH HOH B . CA 10 HOH 137 961 961 HOH HOH B . CA 10 HOH 138 962 962 HOH HOH B . CA 10 HOH 139 963 963 HOH HOH B . CA 10 HOH 140 964 964 HOH HOH B . CA 10 HOH 141 965 965 HOH HOH B . CA 10 HOH 142 966 966 HOH HOH B . CA 10 HOH 143 967 967 HOH HOH B . CA 10 HOH 144 968 968 HOH HOH B . CA 10 HOH 145 969 969 HOH HOH B . CA 10 HOH 146 970 970 HOH HOH B . CA 10 HOH 147 971 971 HOH HOH B . CA 10 HOH 148 972 972 HOH HOH B . CA 10 HOH 149 973 973 HOH HOH B . CA 10 HOH 150 974 974 HOH HOH B . CA 10 HOH 151 975 975 HOH HOH B . CA 10 HOH 152 976 976 HOH HOH B . CA 10 HOH 153 977 977 HOH HOH B . CA 10 HOH 154 978 978 HOH HOH B . CA 10 HOH 155 979 979 HOH HOH B . CA 10 HOH 156 980 980 HOH HOH B . CA 10 HOH 157 981 981 HOH HOH B . CA 10 HOH 158 982 982 HOH HOH B . CA 10 HOH 159 983 983 HOH HOH B . CA 10 HOH 160 984 984 HOH HOH B . CA 10 HOH 161 985 985 HOH HOH B . CA 10 HOH 162 986 986 HOH HOH B . CA 10 HOH 163 987 987 HOH HOH B . CA 10 HOH 164 988 988 HOH HOH B . CA 10 HOH 165 989 989 HOH HOH B . CA 10 HOH 166 990 990 HOH HOH B . CA 10 HOH 167 991 991 HOH HOH B . CA 10 HOH 168 992 992 HOH HOH B . CA 10 HOH 169 993 993 HOH HOH B . CA 10 HOH 170 994 994 HOH HOH B . CA 10 HOH 171 995 995 HOH HOH B . CA 10 HOH 172 996 996 HOH HOH B . CA 10 HOH 173 997 997 HOH HOH B . CA 10 HOH 174 998 998 HOH HOH B . CA 10 HOH 175 999 999 HOH HOH B . CA 10 HOH 176 1000 1000 HOH HOH B . CA 10 HOH 177 1001 1001 HOH HOH B . CA 10 HOH 178 1002 1002 HOH HOH B . CA 10 HOH 179 1003 1003 HOH HOH B . CA 10 HOH 180 1004 1004 HOH HOH B . CA 10 HOH 181 1005 1005 HOH HOH B . CA 10 HOH 182 1006 1006 HOH HOH B . CA 10 HOH 183 1007 1007 HOH HOH B . CA 10 HOH 184 1008 1008 HOH HOH B . CA 10 HOH 185 1009 1009 HOH HOH B . CA 10 HOH 186 1010 1010 HOH HOH B . CA 10 HOH 187 1011 1011 HOH HOH B . CA 10 HOH 188 1012 1012 HOH HOH B . CA 10 HOH 189 1013 1013 HOH HOH B . CA 10 HOH 190 1014 1014 HOH HOH B . CA 10 HOH 191 1015 1015 HOH HOH B . CA 10 HOH 192 1016 1016 HOH HOH B . CA 10 HOH 193 1017 1017 HOH HOH B . CA 10 HOH 194 1018 1018 HOH HOH B . CA 10 HOH 195 1019 1019 HOH HOH B . CA 10 HOH 196 1020 1020 HOH HOH B . CA 10 HOH 197 1021 1021 HOH HOH B . CA 10 HOH 198 1022 1022 HOH HOH B . CA 10 HOH 199 1023 1023 HOH HOH B . CA 10 HOH 200 1024 1024 HOH HOH B . CA 10 HOH 201 1025 1025 HOH HOH B . CA 10 HOH 202 1026 1026 HOH HOH B . CA 10 HOH 203 1027 1027 HOH HOH B . CA 10 HOH 204 1028 1028 HOH HOH B . CA 10 HOH 205 1029 1029 HOH HOH B . CA 10 HOH 206 1030 1030 HOH HOH B . CA 10 HOH 207 1031 1031 HOH HOH B . CA 10 HOH 208 1032 1032 HOH HOH B . CA 10 HOH 209 1033 1033 HOH HOH B . CA 10 HOH 210 1034 1034 HOH HOH B . CA 10 HOH 211 1035 1035 HOH HOH B . CA 10 HOH 212 1036 1036 HOH HOH B . CA 10 HOH 213 1037 1037 HOH HOH B . CA 10 HOH 214 1038 1038 HOH HOH B . CA 10 HOH 215 1039 1039 HOH HOH B . CA 10 HOH 216 1040 1040 HOH HOH B . CA 10 HOH 217 1041 1041 HOH HOH B . CA 10 HOH 218 1042 1042 HOH HOH B . CA 10 HOH 219 1043 1043 HOH HOH B . CA 10 HOH 220 1044 1044 HOH HOH B . CA 10 HOH 221 1045 1045 HOH HOH B . CA 10 HOH 222 1046 1046 HOH HOH B . CA 10 HOH 223 1047 1047 HOH HOH B . CA 10 HOH 224 1048 1048 HOH HOH B . CA 10 HOH 225 1049 1049 HOH HOH B . CA 10 HOH 226 1050 1050 HOH HOH B . CA 10 HOH 227 1051 1051 HOH HOH B . CA 10 HOH 228 1052 1052 HOH HOH B . CA 10 HOH 229 1053 1053 HOH HOH B . CA 10 HOH 230 1054 1054 HOH HOH B . CA 10 HOH 231 1055 1055 HOH HOH B . CA 10 HOH 232 1056 1056 HOH HOH B . CA 10 HOH 233 1057 1057 HOH HOH B . CA 10 HOH 234 1058 1058 HOH HOH B . CA 10 HOH 235 1059 1059 HOH HOH B . CA 10 HOH 236 1060 1060 HOH HOH B . CA 10 HOH 237 1061 1061 HOH HOH B . CA 10 HOH 238 1062 1062 HOH HOH B . CA 10 HOH 239 1063 1063 HOH HOH B . CA 10 HOH 240 1064 1064 HOH HOH B . CA 10 HOH 241 1065 1065 HOH HOH B . CA 10 HOH 242 1066 1066 HOH HOH B . CA 10 HOH 243 1067 1067 HOH HOH B . CA 10 HOH 244 1068 1068 HOH HOH B . CA 10 HOH 245 1069 1069 HOH HOH B . CA 10 HOH 246 1070 1070 HOH HOH B . CA 10 HOH 247 1071 1071 HOH HOH B . CA 10 HOH 248 1072 1072 HOH HOH B . CA 10 HOH 249 1073 1073 HOH HOH B . CA 10 HOH 250 1074 1074 HOH HOH B . CA 10 HOH 251 1075 1075 HOH HOH B . CA 10 HOH 252 1076 1076 HOH HOH B . CA 10 HOH 253 1077 1077 HOH HOH B . CA 10 HOH 254 1078 1078 HOH HOH B . CA 10 HOH 255 1079 1079 HOH HOH B . CA 10 HOH 256 1080 1080 HOH HOH B . CA 10 HOH 257 1081 1081 HOH HOH B . CA 10 HOH 258 1082 1082 HOH HOH B . CA 10 HOH 259 1083 1083 HOH HOH B . CA 10 HOH 260 1084 1084 HOH HOH B . CA 10 HOH 261 1085 1085 HOH HOH B . CA 10 HOH 262 1086 1086 HOH HOH B . CA 10 HOH 263 1087 1087 HOH HOH B . CA 10 HOH 264 1088 1088 HOH HOH B . CA 10 HOH 265 1089 1089 HOH HOH B . CA 10 HOH 266 1090 1090 HOH HOH B . CA 10 HOH 267 1091 1091 HOH HOH B . CA 10 HOH 268 1092 1092 HOH HOH B . CA 10 HOH 269 1093 1093 HOH HOH B . CA 10 HOH 270 1094 1094 HOH HOH B . CA 10 HOH 271 1095 1095 HOH HOH B . CA 10 HOH 272 1096 1096 HOH HOH B . CA 10 HOH 273 1097 1097 HOH HOH B . CA 10 HOH 274 1098 1098 HOH HOH B . CA 10 HOH 275 1099 1099 HOH HOH B . CA 10 HOH 276 1100 1100 HOH HOH B . CA 10 HOH 277 1101 1101 HOH HOH B . CA 10 HOH 278 1102 1102 HOH HOH B . CA 10 HOH 279 1103 1103 HOH HOH B . CA 10 HOH 280 1104 1104 HOH HOH B . CA 10 HOH 281 1105 1105 HOH HOH B . CA 10 HOH 282 1106 1106 HOH HOH B . CA 10 HOH 283 1107 1107 HOH HOH B . CA 10 HOH 284 1108 1108 HOH HOH B . CA 10 HOH 285 1109 1109 HOH HOH B . CA 10 HOH 286 1110 1110 HOH HOH B . CA 10 HOH 287 1111 1111 HOH HOH B . CA 10 HOH 288 1112 1112 HOH HOH B . CA 10 HOH 289 1113 1113 HOH HOH B . CA 10 HOH 290 1114 1114 HOH HOH B . CA 10 HOH 291 1115 1115 HOH HOH B . CA 10 HOH 292 1116 1116 HOH HOH B . CA 10 HOH 293 1117 1117 HOH HOH B . CA 10 HOH 294 1118 1118 HOH HOH B . CA 10 HOH 295 1119 1119 HOH HOH B . CA 10 HOH 296 1120 1120 HOH HOH B . CA 10 HOH 297 1121 1121 HOH HOH B . CA 10 HOH 298 1122 1122 HOH HOH B . CA 10 HOH 299 1123 1123 HOH HOH B . CA 10 HOH 300 1124 1124 HOH HOH B . CA 10 HOH 301 1125 1125 HOH HOH B . CA 10 HOH 302 1126 1126 HOH HOH B . CA 10 HOH 303 1127 1127 HOH HOH B . CA 10 HOH 304 1128 1128 HOH HOH B . CA 10 HOH 305 1129 1129 HOH HOH B . CA 10 HOH 306 1130 1130 HOH HOH B . CA 10 HOH 307 1131 1131 HOH HOH B . CA 10 HOH 308 1132 1132 HOH HOH B . CA 10 HOH 309 1133 1133 HOH HOH B . CA 10 HOH 310 1134 1134 HOH HOH B . CA 10 HOH 311 1135 1135 HOH HOH B . CA 10 HOH 312 1136 1136 HOH HOH B . CA 10 HOH 313 1137 1137 HOH HOH B . CA 10 HOH 314 1138 1138 HOH HOH B . CA 10 HOH 315 1139 1139 HOH HOH B . CA 10 HOH 316 1140 1140 HOH HOH B . CA 10 HOH 317 1141 1141 HOH HOH B . CA 10 HOH 318 1142 1142 HOH HOH B . CA 10 HOH 319 1143 1143 HOH HOH B . CA 10 HOH 320 1144 1144 HOH HOH B . CA 10 HOH 321 1145 1145 HOH HOH B . CA 10 HOH 322 1146 1146 HOH HOH B . CA 10 HOH 323 1147 1147 HOH HOH B . CA 10 HOH 324 1148 1148 HOH HOH B . CA 10 HOH 325 1149 1149 HOH HOH B . CA 10 HOH 326 1150 1150 HOH HOH B . CA 10 HOH 327 1151 1151 HOH HOH B . CA 10 HOH 328 1152 1152 HOH HOH B . CA 10 HOH 329 1153 1153 HOH HOH B . CA 10 HOH 330 1154 1154 HOH HOH B . CA 10 HOH 331 1155 1155 HOH HOH B . CA 10 HOH 332 1156 1156 HOH HOH B . CA 10 HOH 333 1157 1157 HOH HOH B . CA 10 HOH 334 1158 1158 HOH HOH B . CA 10 HOH 335 1159 1159 HOH HOH B . CA 10 HOH 336 1160 1160 HOH HOH B . CA 10 HOH 337 1161 1161 HOH HOH B . CA 10 HOH 338 1162 1162 HOH HOH B . CA 10 HOH 339 1163 1163 HOH HOH B . CA 10 HOH 340 1164 1164 HOH HOH B . CA 10 HOH 341 1165 1165 HOH HOH B . CA 10 HOH 342 1166 1166 HOH HOH B . CA 10 HOH 343 1167 1167 HOH HOH B . CA 10 HOH 344 1168 1168 HOH HOH B . CA 10 HOH 345 1169 1169 HOH HOH B . CA 10 HOH 346 1170 1170 HOH HOH B . CA 10 HOH 347 1171 1171 HOH HOH B . CA 10 HOH 348 1172 1172 HOH HOH B . CA 10 HOH 349 1173 1173 HOH HOH B . CA 10 HOH 350 1174 1174 HOH HOH B . CA 10 HOH 351 1175 1175 HOH HOH B . CA 10 HOH 352 1176 1176 HOH HOH B . CA 10 HOH 353 1177 1177 HOH HOH B . CA 10 HOH 354 1178 1178 HOH HOH B . CA 10 HOH 355 1179 1179 HOH HOH B . CA 10 HOH 356 1180 1180 HOH HOH B . CA 10 HOH 357 1181 1181 HOH HOH B . CA 10 HOH 358 1182 1182 HOH HOH B . CA 10 HOH 359 1183 1183 HOH HOH B . CA 10 HOH 360 1184 1184 HOH HOH B . CA 10 HOH 361 1185 1185 HOH HOH B . CA 10 HOH 362 1186 1186 HOH HOH B . CA 10 HOH 363 1187 1187 HOH HOH B . CA 10 HOH 364 1188 1188 HOH HOH B . CA 10 HOH 365 1189 1189 HOH HOH B . CA 10 HOH 366 1190 1190 HOH HOH B . CA 10 HOH 367 1191 1191 HOH HOH B . CA 10 HOH 368 1192 1192 HOH HOH B . CA 10 HOH 369 1193 1193 HOH HOH B . CA 10 HOH 370 1194 1194 HOH HOH B . CA 10 HOH 371 1195 1195 HOH HOH B . CA 10 HOH 372 1196 1196 HOH HOH B . CA 10 HOH 373 1197 1197 HOH HOH B . CA 10 HOH 374 1198 1198 HOH HOH B . CA 10 HOH 375 1199 1199 HOH HOH B . CA 10 HOH 376 1200 1200 HOH HOH B . CA 10 HOH 377 1201 1201 HOH HOH B . CA 10 HOH 378 1202 1202 HOH HOH B . CA 10 HOH 379 1203 1203 HOH HOH B . CA 10 HOH 380 1204 1204 HOH HOH B . CA 10 HOH 381 1205 1205 HOH HOH B . CA 10 HOH 382 1206 1206 HOH HOH B . CA 10 HOH 383 1207 1207 HOH HOH B . CA 10 HOH 384 1208 1208 HOH HOH B . CA 10 HOH 385 1209 1209 HOH HOH B . CA 10 HOH 386 1210 1210 HOH HOH B . CA 10 HOH 387 1211 1211 HOH HOH B . CA 10 HOH 388 1212 1212 HOH HOH B . CA 10 HOH 389 1213 1213 HOH HOH B . CA 10 HOH 390 1214 1214 HOH HOH B . CA 10 HOH 391 1215 1215 HOH HOH B . CA 10 HOH 392 1216 1216 HOH HOH B . CA 10 HOH 393 1217 1217 HOH HOH B . CA 10 HOH 394 1218 1218 HOH HOH B . CA 10 HOH 395 1219 1219 HOH HOH B . CA 10 HOH 396 1220 1220 HOH HOH B . CA 10 HOH 397 1221 1221 HOH HOH B . CA 10 HOH 398 1222 1222 HOH HOH B . CA 10 HOH 399 1223 1223 HOH HOH B . CA 10 HOH 400 1224 1224 HOH HOH B . CA 10 HOH 401 1225 1225 HOH HOH B . CA 10 HOH 402 1226 1226 HOH HOH B . CA 10 HOH 403 1227 1227 HOH HOH B . CA 10 HOH 404 1228 1228 HOH HOH B . CA 10 HOH 405 1229 1229 HOH HOH B . CA 10 HOH 406 1230 1230 HOH HOH B . CA 10 HOH 407 1231 1231 HOH HOH B . CA 10 HOH 408 1232 1232 HOH HOH B . CA 10 HOH 409 1233 1233 HOH HOH B . CA 10 HOH 410 1234 1234 HOH HOH B . CA 10 HOH 411 1235 1235 HOH HOH B . CA 10 HOH 412 1236 1236 HOH HOH B . CA 10 HOH 413 1237 1237 HOH HOH B . CA 10 HOH 414 1238 1238 HOH HOH B . CA 10 HOH 415 1239 1239 HOH HOH B . CA 10 HOH 416 1240 1240 HOH HOH B . CA 10 HOH 417 1241 1241 HOH HOH B . CA 10 HOH 418 1242 1242 HOH HOH B . CA 10 HOH 419 1243 1243 HOH HOH B . CA 10 HOH 420 1244 1244 HOH HOH B . CA 10 HOH 421 1245 1245 HOH HOH B . CA 10 HOH 422 1246 1246 HOH HOH B . CA 10 HOH 423 1247 1247 HOH HOH B . CA 10 HOH 424 1248 1248 HOH HOH B . CA 10 HOH 425 1249 1249 HOH HOH B . CA 10 HOH 426 1250 1250 HOH HOH B . CA 10 HOH 427 1251 1251 HOH HOH B . CA 10 HOH 428 1252 1252 HOH HOH B . CA 10 HOH 429 1253 1253 HOH HOH B . CA 10 HOH 430 1254 1254 HOH HOH B . CA 10 HOH 431 1255 1255 HOH HOH B . CA 10 HOH 432 1256 1256 HOH HOH B . CA 10 HOH 433 1257 1257 HOH HOH B . CA 10 HOH 434 1258 1258 HOH HOH B . CA 10 HOH 435 1259 1259 HOH HOH B . CA 10 HOH 436 1260 1260 HOH HOH B . CA 10 HOH 437 1261 1261 HOH HOH B . CA 10 HOH 438 1262 1262 HOH HOH B . CA 10 HOH 439 1263 1263 HOH HOH B . CA 10 HOH 440 1264 1264 HOH HOH B . CA 10 HOH 441 1265 1265 HOH HOH B . CA 10 HOH 442 1266 1266 HOH HOH B . CA 10 HOH 443 1267 1267 HOH HOH B . CA 10 HOH 444 1268 1268 HOH HOH B . CA 10 HOH 445 1269 1269 HOH HOH B . CA 10 HOH 446 1270 1270 HOH HOH B . CA 10 HOH 447 1271 1271 HOH HOH B . CA 10 HOH 448 1272 1272 HOH HOH B . CA 10 HOH 449 1273 1273 HOH HOH B . CA 10 HOH 450 1274 1274 HOH HOH B . CA 10 HOH 451 1275 1275 HOH HOH B . CA 10 HOH 452 1276 1276 HOH HOH B . CA 10 HOH 453 1277 1277 HOH HOH B . CA 10 HOH 454 1278 1278 HOH HOH B . CA 10 HOH 455 1279 1279 HOH HOH B . CA 10 HOH 456 1280 1280 HOH HOH B . CA 10 HOH 457 1281 1281 HOH HOH B . CA 10 HOH 458 1282 1282 HOH HOH B . CA 10 HOH 459 1283 1283 HOH HOH B . CA 10 HOH 460 1284 1284 HOH HOH B . CA 10 HOH 461 1285 1285 HOH HOH B . CA 10 HOH 462 1286 1286 HOH HOH B . CA 10 HOH 463 1287 1287 HOH HOH B . CA 10 HOH 464 1288 1288 HOH HOH B . CA 10 HOH 465 1289 1289 HOH HOH B . CA 10 HOH 466 1290 1290 HOH HOH B . CA 10 HOH 467 1291 1291 HOH HOH B . CA 10 HOH 468 1292 1292 HOH HOH B . CA 10 HOH 469 1293 1293 HOH HOH B . CA 10 HOH 470 1294 1294 HOH HOH B . CA 10 HOH 471 1295 1295 HOH HOH B . CA 10 HOH 472 1296 1296 HOH HOH B . CA 10 HOH 473 1297 1297 HOH HOH B . CA 10 HOH 474 1298 1298 HOH HOH B . CA 10 HOH 475 1299 1299 HOH HOH B . CA 10 HOH 476 1300 1300 HOH HOH B . CA 10 HOH 477 1301 1301 HOH HOH B . CA 10 HOH 478 1302 1302 HOH HOH B . CA 10 HOH 479 1303 1303 HOH HOH B . CA 10 HOH 480 1304 1304 HOH HOH B . CA 10 HOH 481 1305 1305 HOH HOH B . CA 10 HOH 482 1306 1306 HOH HOH B . CA 10 HOH 483 1307 1307 HOH HOH B . CA 10 HOH 484 1308 1308 HOH HOH B . CA 10 HOH 485 1309 1309 HOH HOH B . CA 10 HOH 486 1310 1310 HOH HOH B . CA 10 HOH 487 1311 1311 HOH HOH B . CA 10 HOH 488 1313 1313 HOH HOH B . CA 10 HOH 489 1314 1314 HOH HOH B . CA 10 HOH 490 1315 1315 HOH HOH B . CA 10 HOH 491 1316 1316 HOH HOH B . CA 10 HOH 492 1317 1317 HOH HOH B . CA 10 HOH 493 1318 1318 HOH HOH B . CA 10 HOH 494 1319 1319 HOH HOH B . CA 10 HOH 495 1320 1320 HOH HOH B . CA 10 HOH 496 1321 1321 HOH HOH B . CA 10 HOH 497 1322 1322 HOH HOH B . CA 10 HOH 498 1323 1323 HOH HOH B . CA 10 HOH 499 1324 1324 HOH HOH B . CA 10 HOH 500 1325 1325 HOH HOH B . CA 10 HOH 501 1326 1326 HOH HOH B . CA 10 HOH 502 1327 1327 HOH HOH B . CA 10 HOH 503 1328 1328 HOH HOH B . CA 10 HOH 504 1329 1329 HOH HOH B . CA 10 HOH 505 1330 1330 HOH HOH B . CA 10 HOH 506 1331 1331 HOH HOH B . CA 10 HOH 507 1332 1332 HOH HOH B . CA 10 HOH 508 1333 1333 HOH HOH B . CA 10 HOH 509 1334 1334 HOH HOH B . CA 10 HOH 510 1335 1335 HOH HOH B . CA 10 HOH 511 1336 1336 HOH HOH B . CA 10 HOH 512 1337 1337 HOH HOH B . CA 10 HOH 513 1338 1338 HOH HOH B . CA 10 HOH 514 1339 1339 HOH HOH B . CA 10 HOH 515 1340 1340 HOH HOH B . CA 10 HOH 516 1341 1341 HOH HOH B . CA 10 HOH 517 1342 1342 HOH HOH B . CA 10 HOH 518 1343 1343 HOH HOH B . CA 10 HOH 519 1344 1344 HOH HOH B . CA 10 HOH 520 1345 1345 HOH HOH B . CA 10 HOH 521 1346 1346 HOH HOH B . CA 10 HOH 522 1347 1347 HOH HOH B . CA 10 HOH 523 1348 1348 HOH HOH B . CA 10 HOH 524 1349 1349 HOH HOH B . CA 10 HOH 525 1350 1350 HOH HOH B . CA 10 HOH 526 1351 1351 HOH HOH B . CA 10 HOH 527 1352 1352 HOH HOH B . CA 10 HOH 528 1353 1353 HOH HOH B . CA 10 HOH 529 1354 1354 HOH HOH B . CA 10 HOH 530 1355 1355 HOH HOH B . CA 10 HOH 531 1356 1356 HOH HOH B . CA 10 HOH 532 1357 1357 HOH HOH B . CA 10 HOH 533 1358 1358 HOH HOH B . CA 10 HOH 534 1359 1359 HOH HOH B . CA 10 HOH 535 1360 1360 HOH HOH B . CA 10 HOH 536 1361 1361 HOH HOH B . CA 10 HOH 537 1362 1362 HOH HOH B . CA 10 HOH 538 1363 1363 HOH HOH B . CA 10 HOH 539 1364 1364 HOH HOH B . CA 10 HOH 540 1365 1365 HOH HOH B . CA 10 HOH 541 1367 1367 HOH HOH B . CA 10 HOH 542 1368 1368 HOH HOH B . CA 10 HOH 543 1369 1369 HOH HOH B . CA 10 HOH 544 1370 1370 HOH HOH B . CA 10 HOH 545 1371 1371 HOH HOH B . CA 10 HOH 546 1372 1372 HOH HOH B . CA 10 HOH 547 1373 1373 HOH HOH B . CA 10 HOH 548 1374 1374 HOH HOH B . CA 10 HOH 549 1375 1375 HOH HOH B . CA 10 HOH 550 1376 1376 HOH HOH B . CA 10 HOH 551 1377 1377 HOH HOH B . CA 10 HOH 552 1378 1378 HOH HOH B . CA 10 HOH 553 1379 1379 HOH HOH B . CA 10 HOH 554 1380 1380 HOH HOH B . CA 10 HOH 555 1381 1381 HOH HOH B . CA 10 HOH 556 1382 1382 HOH HOH B . CA 10 HOH 557 1383 1383 HOH HOH B . CA 10 HOH 558 1384 1384 HOH HOH B . CA 10 HOH 559 1385 1385 HOH HOH B . CA 10 HOH 560 1386 1386 HOH HOH B . CA 10 HOH 561 1387 1387 HOH HOH B . CA 10 HOH 562 1388 1388 HOH HOH B . CA 10 HOH 563 1389 1389 HOH HOH B . CA 10 HOH 564 1390 1390 HOH HOH B . CA 10 HOH 565 1391 1391 HOH HOH B . CA 10 HOH 566 1392 1392 HOH HOH B . CA 10 HOH 567 1393 1393 HOH HOH B . CA 10 HOH 568 1394 1394 HOH HOH B . CA 10 HOH 569 1395 1395 HOH HOH B . CA 10 HOH 570 1396 1396 HOH HOH B . CA 10 HOH 571 1397 1397 HOH HOH B . CA 10 HOH 572 1398 1398 HOH HOH B . CA 10 HOH 573 1399 1399 HOH HOH B . CA 10 HOH 574 1400 1400 HOH HOH B . CA 10 HOH 575 1401 1401 HOH HOH B . CA 10 HOH 576 1402 1402 HOH HOH B . CA 10 HOH 577 1403 1403 HOH HOH B . CA 10 HOH 578 1404 1404 HOH HOH B . CA 10 HOH 579 1405 1405 HOH HOH B . CA 10 HOH 580 1406 1406 HOH HOH B . CA 10 HOH 581 1407 1407 HOH HOH B . CA 10 HOH 582 1408 1408 HOH HOH B . CA 10 HOH 583 1409 1409 HOH HOH B . CA 10 HOH 584 1410 1410 HOH HOH B . CA 10 HOH 585 1411 1411 HOH HOH B . CA 10 HOH 586 1412 1412 HOH HOH B . CA 10 HOH 587 1413 1413 HOH HOH B . CA 10 HOH 588 1414 1414 HOH HOH B . CA 10 HOH 589 1415 1415 HOH HOH B . CA 10 HOH 590 1416 1416 HOH HOH B . CA 10 HOH 591 1417 1417 HOH HOH B . CA 10 HOH 592 1418 1418 HOH HOH B . CA 10 HOH 593 1419 1419 HOH HOH B . CA 10 HOH 594 1420 1420 HOH HOH B . CA 10 HOH 595 1421 1421 HOH HOH B . CA 10 HOH 596 1422 1422 HOH HOH B . CA 10 HOH 597 1423 1423 HOH HOH B . CA 10 HOH 598 1424 1424 HOH HOH B . CA 10 HOH 599 1425 1425 HOH HOH B . CA 10 HOH 600 1426 1426 HOH HOH B . CA 10 HOH 601 1427 1427 HOH HOH B . CA 10 HOH 602 1428 1428 HOH HOH B . CA 10 HOH 603 1429 1429 HOH HOH B . CA 10 HOH 604 1430 1430 HOH HOH B . CA 10 HOH 605 1431 1431 HOH HOH B . CA 10 HOH 606 1432 1432 HOH HOH B . CA 10 HOH 607 1433 1433 HOH HOH B . CA 10 HOH 608 1434 1434 HOH HOH B . CA 10 HOH 609 1435 1435 HOH HOH B . CA 10 HOH 610 1436 1436 HOH HOH B . CA 10 HOH 611 1437 1437 HOH HOH B . CA 10 HOH 612 1438 1438 HOH HOH B . CA 10 HOH 613 1439 1439 HOH HOH B . CA 10 HOH 614 1440 1440 HOH HOH B . CA 10 HOH 615 1441 1441 HOH HOH B . CA 10 HOH 616 1442 1442 HOH HOH B . CA 10 HOH 617 1443 1443 HOH HOH B . CA 10 HOH 618 1444 1444 HOH HOH B . CA 10 HOH 619 1445 1445 HOH HOH B . CA 10 HOH 620 1446 1446 HOH HOH B . CA 10 HOH 621 1447 1447 HOH HOH B . CA 10 HOH 622 1448 1448 HOH HOH B . CA 10 HOH 623 1449 1449 HOH HOH B . CA 10 HOH 624 1450 1450 HOH HOH B . CA 10 HOH 625 1451 1451 HOH HOH B . CA 10 HOH 626 1452 1452 HOH HOH B . CA 10 HOH 627 1453 1453 HOH HOH B . CA 10 HOH 628 1454 1454 HOH HOH B . CA 10 HOH 629 1455 1455 HOH HOH B . CA 10 HOH 630 1456 1456 HOH HOH B . CA 10 HOH 631 1457 1457 HOH HOH B . CA 10 HOH 632 1458 1458 HOH HOH B . CA 10 HOH 633 1459 1459 HOH HOH B . CA 10 HOH 634 1460 1460 HOH HOH B . CA 10 HOH 635 1461 1461 HOH HOH B . CA 10 HOH 636 1462 1462 HOH HOH B . CA 10 HOH 637 1464 1464 HOH HOH B . CA 10 HOH 638 1465 1465 HOH HOH B . CA 10 HOH 639 1466 1466 HOH HOH B . CA 10 HOH 640 1467 1467 HOH HOH B . CA 10 HOH 641 1468 1468 HOH HOH B . CA 10 HOH 642 1469 1469 HOH HOH B . CA 10 HOH 643 1470 1470 HOH HOH B . CA 10 HOH 644 1471 1471 HOH HOH B . CA 10 HOH 645 1472 1472 HOH HOH B . CA 10 HOH 646 1473 1473 HOH HOH B . CA 10 HOH 647 1474 1474 HOH HOH B . CA 10 HOH 648 1475 1475 HOH HOH B . CA 10 HOH 649 1476 1476 HOH HOH B . CA 10 HOH 650 1477 1477 HOH HOH B . CA 10 HOH 651 1478 1478 HOH HOH B . CA 10 HOH 652 1479 1479 HOH HOH B . CA 10 HOH 653 1480 1480 HOH HOH B . CA 10 HOH 654 1481 1481 HOH HOH B . CA 10 HOH 655 1482 1482 HOH HOH B . CA 10 HOH 656 1483 1483 HOH HOH B . CA 10 HOH 657 1484 1484 HOH HOH B . CA 10 HOH 658 1485 1485 HOH HOH B . CA 10 HOH 659 1486 1486 HOH HOH B . CA 10 HOH 660 1487 1487 HOH HOH B . CA 10 HOH 661 1488 1488 HOH HOH B . CA 10 HOH 662 1489 1489 HOH HOH B . CA 10 HOH 663 1490 1490 HOH HOH B . CA 10 HOH 664 1491 1491 HOH HOH B . CA 10 HOH 665 1492 1492 HOH HOH B . CA 10 HOH 666 1493 1493 HOH HOH B . CA 10 HOH 667 1494 1494 HOH HOH B . CA 10 HOH 668 1495 1495 HOH HOH B . CA 10 HOH 669 1496 1496 HOH HOH B . CA 10 HOH 670 1497 1497 HOH HOH B . CA 10 HOH 671 1498 1498 HOH HOH B . CA 10 HOH 672 1499 1499 HOH HOH B . CA 10 HOH 673 1500 1500 HOH HOH B . CA 10 HOH 674 1501 1501 HOH HOH B . CA 10 HOH 675 1502 1502 HOH HOH B . CA 10 HOH 676 1503 1503 HOH HOH B . CA 10 HOH 677 1505 1505 HOH HOH B . CA 10 HOH 678 1506 1506 HOH HOH B . CA 10 HOH 679 1507 1507 HOH HOH B . CA 10 HOH 680 1508 1508 HOH HOH B . CA 10 HOH 681 1509 1509 HOH HOH B . CA 10 HOH 682 1510 1510 HOH HOH B . CA 10 HOH 683 1511 1511 HOH HOH B . CA 10 HOH 684 1512 1512 HOH HOH B . CA 10 HOH 685 1513 1513 HOH HOH B . CA 10 HOH 686 1514 1514 HOH HOH B . CA 10 HOH 687 1515 1515 HOH HOH B . CA 10 HOH 688 1516 1516 HOH HOH B . CA 10 HOH 689 1517 1517 HOH HOH B . CA 10 HOH 690 1518 1518 HOH HOH B . CA 10 HOH 691 1519 1519 HOH HOH B . CA 10 HOH 692 1520 1520 HOH HOH B . CA 10 HOH 693 1521 1521 HOH HOH B . CA 10 HOH 694 1522 1522 HOH HOH B . CA 10 HOH 695 1523 1523 HOH HOH B . CA 10 HOH 696 1524 1524 HOH HOH B . CA 10 HOH 697 1525 1525 HOH HOH B . CA 10 HOH 698 1526 1526 HOH HOH B . CA 10 HOH 699 1527 1527 HOH HOH B . CA 10 HOH 700 1528 1528 HOH HOH B . CA 10 HOH 701 1529 1529 HOH HOH B . CA 10 HOH 702 1530 1530 HOH HOH B . CA 10 HOH 703 1531 1531 HOH HOH B . CA 10 HOH 704 1532 1532 HOH HOH B . CA 10 HOH 705 1533 1533 HOH HOH B . CA 10 HOH 706 1534 1534 HOH HOH B . CA 10 HOH 707 1536 1536 HOH HOH B . CA 10 HOH 708 1537 1537 HOH HOH B . CA 10 HOH 709 1538 1538 HOH HOH B . CA 10 HOH 710 1539 1539 HOH HOH B . CA 10 HOH 711 1540 1540 HOH HOH B . CA 10 HOH 712 1541 1541 HOH HOH B . CA 10 HOH 713 1542 1542 HOH HOH B . CA 10 HOH 714 1543 1543 HOH HOH B . CA 10 HOH 715 1544 1544 HOH HOH B . CA 10 HOH 716 1545 1545 HOH HOH B . CA 10 HOH 717 1546 1546 HOH HOH B . CA 10 HOH 718 1547 1547 HOH HOH B . CA 10 HOH 719 1548 1548 HOH HOH B . CA 10 HOH 720 1549 1549 HOH HOH B . CA 10 HOH 721 1550 1550 HOH HOH B . CA 10 HOH 722 1551 1551 HOH HOH B . CA 10 HOH 723 1552 1552 HOH HOH B . CA 10 HOH 724 1553 1553 HOH HOH B . CA 10 HOH 725 1554 1554 HOH HOH B . CA 10 HOH 726 1555 1555 HOH HOH B . CA 10 HOH 727 1556 1556 HOH HOH B . CA 10 HOH 728 1557 1557 HOH HOH B . CA 10 HOH 729 1558 1558 HOH HOH B . CA 10 HOH 730 1559 1559 HOH HOH B . CA 10 HOH 731 1560 1560 HOH HOH B . CA 10 HOH 732 1561 1561 HOH HOH B . CA 10 HOH 733 1562 1562 HOH HOH B . CA 10 HOH 734 1563 1563 HOH HOH B . CA 10 HOH 735 1564 1564 HOH HOH B . CA 10 HOH 736 1565 1565 HOH HOH B . CA 10 HOH 737 1566 1566 HOH HOH B . CA 10 HOH 738 1567 1567 HOH HOH B . CA 10 HOH 739 1569 1569 HOH HOH B . CA 10 HOH 740 1570 1570 HOH HOH B . CA 10 HOH 741 1571 1571 HOH HOH B . CA 10 HOH 742 1573 1573 HOH HOH B . CA 10 HOH 743 1574 1574 HOH HOH B . CA 10 HOH 744 1575 1575 HOH HOH B . CA 10 HOH 745 1576 1576 HOH HOH B . CA 10 HOH 746 1577 1577 HOH HOH B . CA 10 HOH 747 1578 1578 HOH HOH B . CA 10 HOH 748 1579 1579 HOH HOH B . CA 10 HOH 749 1580 1580 HOH HOH B . CA 10 HOH 750 1581 1581 HOH HOH B . CA 10 HOH 751 1582 1582 HOH HOH B . CA 10 HOH 752 1583 1583 HOH HOH B . CA 10 HOH 753 1585 1585 HOH HOH B . CA 10 HOH 754 1586 1586 HOH HOH B . CA 10 HOH 755 1587 1587 HOH HOH B . CA 10 HOH 756 1588 1588 HOH HOH B . CA 10 HOH 757 1589 1589 HOH HOH B . CA 10 HOH 758 1590 1590 HOH HOH B . CA 10 HOH 759 1591 1591 HOH HOH B . CA 10 HOH 760 1592 1592 HOH HOH B . CA 10 HOH 761 1593 1593 HOH HOH B . CA 10 HOH 762 1594 1594 HOH HOH B . CA 10 HOH 763 1595 1595 HOH HOH B . CA 10 HOH 764 1596 1596 HOH HOH B . CA 10 HOH 765 1597 1597 HOH HOH B . CA 10 HOH 766 1598 1598 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 118 A ASN 118 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 135 A ASN 135 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 352 A ASN 352 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 392 A ASN 392 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 118 B ASN 118 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 135 B ASN 135 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 392 B ASN 392 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,H,I,J,K,L,M,N,BA 2 1 B,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,CA # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2009-03-24 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal CNS 1.2 ? package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns-online.org/ Fortran_77 ? 1 PDB_EXTRACT 3.006 'June 11, 2008' package PDB help@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 2 MAR345dtb . ? ? ? ? 'data collection' ? ? ? 3 DENZO . ? ? ? ? 'data reduction' ? ? ? 4 SCALEPACK . ? ? ? ? 'data scaling' ? ? ? 5 AMoRE . ? ? ? ? phasing ? ? ? 6 # _pdbx_entry_details.sequence_details ;AUTHORS STATE THAT SINCE THE PROTEIN WAS PURIFIED FROM A NATURAL SOURCE, THIS DIFFERENCE BETWEEN THE DEPOSITED SEQUENCE AND UNIPROT DATABASE COULD INDICATE NATURAL VARIATION. ; _pdbx_entry_details.entry_id 3GDP _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 ND2 B ASN 352 ? ? C1 B NDG 533 ? ? 1.46 2 1 NH1 A ARG 475 ? B O A HOH 1007 ? ? 1.60 3 1 OD1 B ASP 70 ? B O B HOH 1555 ? ? 2.02 4 1 NH1 A ARG 210 ? B O A HOH 959 ? ? 2.10 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ARG A 101 ? ? -150.68 74.61 2 1 LYS A 250 ? ? 72.62 -7.11 3 1 TYR A 390 ? ? 59.27 18.93 4 1 CYS A 464 ? ? -154.85 60.14 5 1 LYS A 468 ? ? -122.28 -51.16 6 1 ASP A 486 ? ? 179.67 -163.86 7 1 ARG B 101 ? ? -150.73 73.06 8 1 LYS B 250 ? ? 69.57 -5.59 9 1 CYS B 464 ? ? -156.70 61.73 10 1 ASP B 486 ? ? -177.67 -164.69 # _pdbx_unobs_or_zero_occ_atoms.id 1 _pdbx_unobs_or_zero_occ_atoms.PDB_model_num 1 _pdbx_unobs_or_zero_occ_atoms.polymer_flag N _pdbx_unobs_or_zero_occ_atoms.occupancy_flag 1 _pdbx_unobs_or_zero_occ_atoms.auth_asym_id B _pdbx_unobs_or_zero_occ_atoms.auth_comp_id NDG _pdbx_unobs_or_zero_occ_atoms.auth_seq_id 533 _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code ? _pdbx_unobs_or_zero_occ_atoms.auth_atom_id O1L _pdbx_unobs_or_zero_occ_atoms.label_alt_id ? _pdbx_unobs_or_zero_occ_atoms.label_asym_id M _pdbx_unobs_or_zero_occ_atoms.label_comp_id NDG _pdbx_unobs_or_zero_occ_atoms.label_seq_id 1 _pdbx_unobs_or_zero_occ_atoms.label_atom_id O1L # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'ISOPROPYL ALCOHOL' IPA 3 'FLAVIN-ADENINE DINUCLEOTIDE' FAD 4 N-ACETYL-D-GLUCOSAMINE NAG 5 BETA-L-FUCOSE FUL 6 ALPHA-D-MANNOSE MAN 7 ALPHA-L-FUCOSE FUC 8 BETA-D-MANNOSE BMA 9 '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' NDG 10 water HOH #