data_3CTT # _entry.id 3CTT # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3CTT RCSB RCSB047200 WWPDB D_1000047200 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 2qly 'Apo enzyme' unspecified PDB 2qmj 'Same enzyme in complex with Acarbose' unspecified # _pdbx_database_status.entry_id 3CTT _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2008-04-14 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry . _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sim, L.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families ; _citation.journal_abbrev Chemistry _citation.journal_volume 15 _citation.page_first 1627 _citation.page_last 1636 _citation.year 2009 _citation.journal_id_ASTM ? _citation.country GE _citation.journal_id_ISSN 0947-6539 _citation.journal_id_CSD ? _citation.book_publisher ? _citation.pdbx_database_id_PubMed 19123216 _citation.pdbx_database_id_DOI 10.1002/chem.200801578 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Cardona, F.' 1 primary 'Parmeggiani, C.' 2 primary 'Faggi, E.' 3 primary 'Bonaccini, C.' 4 primary 'Gratteri, P.' 5 primary 'Sim, L.' 6 primary 'Gloster, T.M.' 7 primary 'Roberts, S.' 8 primary 'Davies, G.J.' 9 primary 'Rose, D.R.' 10 primary 'Goti, A.' 11 # _cell.length_a 86.692 _cell.length_b 109.131 _cell.length_c 109.438 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3CTT _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3CTT _symmetry.Int_Tables_number 19 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Maltase-glucoamylase 98585.992 1 3.2.1.20 ? 'N-terminal subunit (UNP residues 87-954)' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 2 ? ? ? ? 3 non-polymer syn 'SULFATE ION' 96.063 1 ? ? ? ? 4 non-polymer syn CASUARINE 205.208 1 ? ? ? ? 5 non-polymer syn GLYCEROL 92.094 9 ? ? ? ? 6 water nat water 18.015 352 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAH ; _entity_poly.pdbx_seq_one_letter_code_can ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAH ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 ALA n 1 3 GLU n 1 4 CYS n 1 5 PRO n 1 6 VAL n 1 7 VAL n 1 8 ASN n 1 9 GLU n 1 10 LEU n 1 11 GLU n 1 12 ARG n 1 13 ILE n 1 14 ASN n 1 15 CYS n 1 16 ILE n 1 17 PRO n 1 18 ASP n 1 19 GLN n 1 20 PRO n 1 21 PRO n 1 22 THR n 1 23 LYS n 1 24 ALA n 1 25 THR n 1 26 CYS n 1 27 ASP n 1 28 GLN n 1 29 ARG n 1 30 GLY n 1 31 CYS n 1 32 CYS n 1 33 TRP n 1 34 ASN n 1 35 PRO n 1 36 GLN n 1 37 GLY n 1 38 ALA n 1 39 VAL n 1 40 SER n 1 41 VAL n 1 42 PRO n 1 43 TRP n 1 44 CYS n 1 45 TYR n 1 46 TYR n 1 47 SER n 1 48 LYS n 1 49 ASN n 1 50 HIS n 1 51 SER n 1 52 TYR n 1 53 HIS n 1 54 VAL n 1 55 GLU n 1 56 GLY n 1 57 ASN n 1 58 LEU n 1 59 VAL n 1 60 ASN n 1 61 THR n 1 62 ASN n 1 63 ALA n 1 64 GLY n 1 65 PHE n 1 66 THR n 1 67 ALA n 1 68 ARG n 1 69 LEU n 1 70 LYS n 1 71 ASN n 1 72 LEU n 1 73 PRO n 1 74 SER n 1 75 SER n 1 76 PRO n 1 77 VAL n 1 78 PHE n 1 79 GLY n 1 80 SER n 1 81 ASN n 1 82 VAL n 1 83 ASP n 1 84 ASN n 1 85 VAL n 1 86 LEU n 1 87 LEU n 1 88 THR n 1 89 ALA n 1 90 GLU n 1 91 TYR n 1 92 GLN n 1 93 THR n 1 94 SER n 1 95 ASN n 1 96 ARG n 1 97 PHE n 1 98 HIS n 1 99 PHE n 1 100 LYS n 1 101 LEU n 1 102 THR n 1 103 ASP n 1 104 GLN n 1 105 THR n 1 106 ASN n 1 107 ASN n 1 108 ARG n 1 109 PHE n 1 110 GLU n 1 111 VAL n 1 112 PRO n 1 113 HIS n 1 114 GLU n 1 115 HIS n 1 116 VAL n 1 117 GLN n 1 118 SER n 1 119 PHE n 1 120 SER n 1 121 GLY n 1 122 ASN n 1 123 ALA n 1 124 ALA n 1 125 ALA n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 TYR n 1 130 GLN n 1 131 VAL n 1 132 GLU n 1 133 ILE n 1 134 SER n 1 135 ARG n 1 136 GLN n 1 137 PRO n 1 138 PHE n 1 139 SER n 1 140 ILE n 1 141 LYS n 1 142 VAL n 1 143 THR n 1 144 ARG n 1 145 ARG n 1 146 SER n 1 147 ASN n 1 148 ASN n 1 149 ARG n 1 150 VAL n 1 151 LEU n 1 152 PHE n 1 153 ASP n 1 154 SER n 1 155 SER n 1 156 ILE n 1 157 GLY n 1 158 PRO n 1 159 LEU n 1 160 LEU n 1 161 PHE n 1 162 ALA n 1 163 ASP n 1 164 GLN n 1 165 PHE n 1 166 LEU n 1 167 GLN n 1 168 LEU n 1 169 SER n 1 170 THR n 1 171 ARG n 1 172 LEU n 1 173 PRO n 1 174 SER n 1 175 THR n 1 176 ASN n 1 177 VAL n 1 178 TYR n 1 179 GLY n 1 180 LEU n 1 181 GLY n 1 182 GLU n 1 183 HIS n 1 184 VAL n 1 185 HIS n 1 186 GLN n 1 187 GLN n 1 188 TYR n 1 189 ARG n 1 190 HIS n 1 191 ASP n 1 192 MET n 1 193 ASN n 1 194 TRP n 1 195 LYS n 1 196 THR n 1 197 TRP n 1 198 PRO n 1 199 ILE n 1 200 PHE n 1 201 ASN n 1 202 ARG n 1 203 ASP n 1 204 THR n 1 205 THR n 1 206 PRO n 1 207 ASN n 1 208 GLY n 1 209 ASN n 1 210 GLY n 1 211 THR n 1 212 ASN n 1 213 LEU n 1 214 TYR n 1 215 GLY n 1 216 ALA n 1 217 GLN n 1 218 THR n 1 219 PHE n 1 220 PHE n 1 221 LEU n 1 222 CYS n 1 223 LEU n 1 224 GLU n 1 225 ASP n 1 226 ALA n 1 227 SER n 1 228 GLY n 1 229 LEU n 1 230 SER n 1 231 PHE n 1 232 GLY n 1 233 VAL n 1 234 PHE n 1 235 LEU n 1 236 MET n 1 237 ASN n 1 238 SER n 1 239 ASN n 1 240 ALA n 1 241 MET n 1 242 GLU n 1 243 VAL n 1 244 VAL n 1 245 LEU n 1 246 GLN n 1 247 PRO n 1 248 ALA n 1 249 PRO n 1 250 ALA n 1 251 ILE n 1 252 THR n 1 253 TYR n 1 254 ARG n 1 255 THR n 1 256 ILE n 1 257 GLY n 1 258 GLY n 1 259 ILE n 1 260 LEU n 1 261 ASP n 1 262 PHE n 1 263 TYR n 1 264 VAL n 1 265 PHE n 1 266 LEU n 1 267 GLY n 1 268 ASN n 1 269 THR n 1 270 PRO n 1 271 GLU n 1 272 GLN n 1 273 VAL n 1 274 VAL n 1 275 GLN n 1 276 GLU n 1 277 TYR n 1 278 LEU n 1 279 GLU n 1 280 LEU n 1 281 ILE n 1 282 GLY n 1 283 ARG n 1 284 PRO n 1 285 ALA n 1 286 LEU n 1 287 PRO n 1 288 SER n 1 289 TYR n 1 290 TRP n 1 291 ALA n 1 292 LEU n 1 293 GLY n 1 294 PHE n 1 295 HIS n 1 296 LEU n 1 297 SER n 1 298 ARG n 1 299 TYR n 1 300 GLU n 1 301 TYR n 1 302 GLY n 1 303 THR n 1 304 LEU n 1 305 ASP n 1 306 ASN n 1 307 MET n 1 308 ARG n 1 309 GLU n 1 310 VAL n 1 311 VAL n 1 312 GLU n 1 313 ARG n 1 314 ASN n 1 315 ARG n 1 316 ALA n 1 317 ALA n 1 318 GLN n 1 319 LEU n 1 320 PRO n 1 321 TYR n 1 322 ASP n 1 323 VAL n 1 324 GLN n 1 325 HIS n 1 326 ALA n 1 327 ASP n 1 328 ILE n 1 329 ASP n 1 330 TYR n 1 331 MET n 1 332 ASP n 1 333 GLU n 1 334 ARG n 1 335 ARG n 1 336 ASP n 1 337 PHE n 1 338 THR n 1 339 TYR n 1 340 ASP n 1 341 SER n 1 342 VAL n 1 343 ASP n 1 344 PHE n 1 345 LYS n 1 346 GLY n 1 347 PHE n 1 348 PRO n 1 349 GLU n 1 350 PHE n 1 351 VAL n 1 352 ASN n 1 353 GLU n 1 354 LEU n 1 355 HIS n 1 356 ASN n 1 357 ASN n 1 358 GLY n 1 359 GLN n 1 360 LYS n 1 361 LEU n 1 362 VAL n 1 363 ILE n 1 364 ILE n 1 365 VAL n 1 366 ASP n 1 367 PRO n 1 368 ALA n 1 369 ILE n 1 370 SER n 1 371 ASN n 1 372 ASN n 1 373 SER n 1 374 SER n 1 375 SER n 1 376 SER n 1 377 LYS n 1 378 PRO n 1 379 TYR n 1 380 GLY n 1 381 PRO n 1 382 TYR n 1 383 ASP n 1 384 ARG n 1 385 GLY n 1 386 SER n 1 387 ASP n 1 388 MET n 1 389 LYS n 1 390 ILE n 1 391 TRP n 1 392 VAL n 1 393 ASN n 1 394 SER n 1 395 SER n 1 396 ASP n 1 397 GLY n 1 398 VAL n 1 399 THR n 1 400 PRO n 1 401 LEU n 1 402 ILE n 1 403 GLY n 1 404 GLU n 1 405 VAL n 1 406 TRP n 1 407 PRO n 1 408 GLY n 1 409 GLN n 1 410 THR n 1 411 VAL n 1 412 PHE n 1 413 PRO n 1 414 ASP n 1 415 TYR n 1 416 THR n 1 417 ASN n 1 418 PRO n 1 419 ASN n 1 420 CYS n 1 421 ALA n 1 422 VAL n 1 423 TRP n 1 424 TRP n 1 425 THR n 1 426 LYS n 1 427 GLU n 1 428 PHE n 1 429 GLU n 1 430 LEU n 1 431 PHE n 1 432 HIS n 1 433 ASN n 1 434 GLN n 1 435 VAL n 1 436 GLU n 1 437 PHE n 1 438 ASP n 1 439 GLY n 1 440 ILE n 1 441 TRP n 1 442 ILE n 1 443 ASP n 1 444 MET n 1 445 ASN n 1 446 GLU n 1 447 VAL n 1 448 SER n 1 449 ASN n 1 450 PHE n 1 451 VAL n 1 452 ASP n 1 453 GLY n 1 454 SER n 1 455 VAL n 1 456 SER n 1 457 GLY n 1 458 CYS n 1 459 SER n 1 460 THR n 1 461 ASN n 1 462 ASN n 1 463 LEU n 1 464 ASN n 1 465 ASN n 1 466 PRO n 1 467 PRO n 1 468 PHE n 1 469 THR n 1 470 PRO n 1 471 ARG n 1 472 ILE n 1 473 LEU n 1 474 ASP n 1 475 GLY n 1 476 TYR n 1 477 LEU n 1 478 PHE n 1 479 CYS n 1 480 LYS n 1 481 THR n 1 482 LEU n 1 483 CYS n 1 484 MET n 1 485 ASP n 1 486 ALA n 1 487 VAL n 1 488 GLN n 1 489 HIS n 1 490 TRP n 1 491 GLY n 1 492 LYS n 1 493 GLN n 1 494 TYR n 1 495 ASP n 1 496 ILE n 1 497 HIS n 1 498 ASN n 1 499 LEU n 1 500 TYR n 1 501 GLY n 1 502 TYR n 1 503 SER n 1 504 MET n 1 505 ALA n 1 506 VAL n 1 507 ALA n 1 508 THR n 1 509 ALA n 1 510 GLU n 1 511 ALA n 1 512 ALA n 1 513 LYS n 1 514 THR n 1 515 VAL n 1 516 PHE n 1 517 PRO n 1 518 ASN n 1 519 LYS n 1 520 ARG n 1 521 SER n 1 522 PHE n 1 523 ILE n 1 524 LEU n 1 525 THR n 1 526 ARG n 1 527 SER n 1 528 THR n 1 529 PHE n 1 530 ALA n 1 531 GLY n 1 532 SER n 1 533 GLY n 1 534 LYS n 1 535 PHE n 1 536 ALA n 1 537 ALA n 1 538 HIS n 1 539 TRP n 1 540 LEU n 1 541 GLY n 1 542 ASP n 1 543 ASN n 1 544 THR n 1 545 ALA n 1 546 THR n 1 547 TRP n 1 548 ASP n 1 549 ASP n 1 550 LEU n 1 551 ARG n 1 552 TRP n 1 553 SER n 1 554 ILE n 1 555 PRO n 1 556 GLY n 1 557 VAL n 1 558 LEU n 1 559 GLU n 1 560 PHE n 1 561 ASN n 1 562 LEU n 1 563 PHE n 1 564 GLY n 1 565 ILE n 1 566 PRO n 1 567 MET n 1 568 VAL n 1 569 GLY n 1 570 PRO n 1 571 ASP n 1 572 ILE n 1 573 CYS n 1 574 GLY n 1 575 PHE n 1 576 ALA n 1 577 LEU n 1 578 ASP n 1 579 THR n 1 580 PRO n 1 581 GLU n 1 582 GLU n 1 583 LEU n 1 584 CYS n 1 585 ARG n 1 586 ARG n 1 587 TRP n 1 588 MET n 1 589 GLN n 1 590 LEU n 1 591 GLY n 1 592 ALA n 1 593 PHE n 1 594 TYR n 1 595 PRO n 1 596 PHE n 1 597 SER n 1 598 ARG n 1 599 ASN n 1 600 HIS n 1 601 ASN n 1 602 GLY n 1 603 GLN n 1 604 GLY n 1 605 TYR n 1 606 LYS n 1 607 ASP n 1 608 GLN n 1 609 ASP n 1 610 PRO n 1 611 ALA n 1 612 SER n 1 613 PHE n 1 614 GLY n 1 615 ALA n 1 616 ASP n 1 617 SER n 1 618 LEU n 1 619 LEU n 1 620 LEU n 1 621 ASN n 1 622 SER n 1 623 SER n 1 624 ARG n 1 625 HIS n 1 626 TYR n 1 627 LEU n 1 628 ASN n 1 629 ILE n 1 630 ARG n 1 631 TYR n 1 632 THR n 1 633 LEU n 1 634 LEU n 1 635 PRO n 1 636 TYR n 1 637 LEU n 1 638 TYR n 1 639 THR n 1 640 LEU n 1 641 PHE n 1 642 PHE n 1 643 ARG n 1 644 ALA n 1 645 HIS n 1 646 SER n 1 647 ARG n 1 648 GLY n 1 649 ASP n 1 650 THR n 1 651 VAL n 1 652 ALA n 1 653 ARG n 1 654 PRO n 1 655 LEU n 1 656 LEU n 1 657 HIS n 1 658 GLU n 1 659 PHE n 1 660 TYR n 1 661 GLU n 1 662 ASP n 1 663 ASN n 1 664 SER n 1 665 THR n 1 666 TRP n 1 667 ASP n 1 668 VAL n 1 669 HIS n 1 670 GLN n 1 671 GLN n 1 672 PHE n 1 673 LEU n 1 674 TRP n 1 675 GLY n 1 676 PRO n 1 677 GLY n 1 678 LEU n 1 679 LEU n 1 680 ILE n 1 681 THR n 1 682 PRO n 1 683 VAL n 1 684 LEU n 1 685 ASP n 1 686 GLU n 1 687 GLY n 1 688 ALA n 1 689 GLU n 1 690 LYS n 1 691 VAL n 1 692 MET n 1 693 ALA n 1 694 TYR n 1 695 VAL n 1 696 PRO n 1 697 ASP n 1 698 ALA n 1 699 VAL n 1 700 TRP n 1 701 TYR n 1 702 ASP n 1 703 TYR n 1 704 GLU n 1 705 THR n 1 706 GLY n 1 707 SER n 1 708 GLN n 1 709 VAL n 1 710 ARG n 1 711 TRP n 1 712 ARG n 1 713 LYS n 1 714 GLN n 1 715 LYS n 1 716 VAL n 1 717 GLU n 1 718 MET n 1 719 GLU n 1 720 LEU n 1 721 PRO n 1 722 GLY n 1 723 ASP n 1 724 LYS n 1 725 ILE n 1 726 GLY n 1 727 LEU n 1 728 HIS n 1 729 LEU n 1 730 ARG n 1 731 GLY n 1 732 GLY n 1 733 TYR n 1 734 ILE n 1 735 PHE n 1 736 PRO n 1 737 THR n 1 738 GLN n 1 739 GLN n 1 740 PRO n 1 741 ASN n 1 742 THR n 1 743 THR n 1 744 THR n 1 745 LEU n 1 746 ALA n 1 747 SER n 1 748 ARG n 1 749 LYS n 1 750 ASN n 1 751 PRO n 1 752 LEU n 1 753 GLY n 1 754 LEU n 1 755 ILE n 1 756 ILE n 1 757 ALA n 1 758 LEU n 1 759 ASP n 1 760 GLU n 1 761 ASN n 1 762 LYS n 1 763 GLU n 1 764 ALA n 1 765 LYS n 1 766 GLY n 1 767 GLU n 1 768 LEU n 1 769 PHE n 1 770 TRP n 1 771 ASP n 1 772 ASP n 1 773 GLY n 1 774 GLU n 1 775 THR n 1 776 LYS n 1 777 ASP n 1 778 THR n 1 779 VAL n 1 780 ALA n 1 781 ASN n 1 782 LYS n 1 783 VAL n 1 784 TYR n 1 785 LEU n 1 786 LEU n 1 787 CYS n 1 788 GLU n 1 789 PHE n 1 790 SER n 1 791 VAL n 1 792 THR n 1 793 GLN n 1 794 ASN n 1 795 ARG n 1 796 LEU n 1 797 GLU n 1 798 VAL n 1 799 ASN n 1 800 ILE n 1 801 SER n 1 802 GLN n 1 803 SER n 1 804 THR n 1 805 TYR n 1 806 LYS n 1 807 ASP n 1 808 PRO n 1 809 ASN n 1 810 ASN n 1 811 LEU n 1 812 ALA n 1 813 PHE n 1 814 ASN n 1 815 GLU n 1 816 ILE n 1 817 LYS n 1 818 ILE n 1 819 LEU n 1 820 GLY n 1 821 THR n 1 822 GLU n 1 823 GLU n 1 824 PRO n 1 825 SER n 1 826 ASN n 1 827 VAL n 1 828 THR n 1 829 VAL n 1 830 LYS n 1 831 HIS n 1 832 ASN n 1 833 GLY n 1 834 VAL n 1 835 PRO n 1 836 SER n 1 837 GLN n 1 838 THR n 1 839 SER n 1 840 PRO n 1 841 THR n 1 842 VAL n 1 843 THR n 1 844 TYR n 1 845 ASP n 1 846 SER n 1 847 ASN n 1 848 LEU n 1 849 LYS n 1 850 VAL n 1 851 ALA n 1 852 ILE n 1 853 ILE n 1 854 THR n 1 855 ASP n 1 856 ILE n 1 857 ASP n 1 858 LEU n 1 859 LEU n 1 860 LEU n 1 861 GLY n 1 862 GLU n 1 863 ALA n 1 864 TYR n 1 865 THR n 1 866 VAL n 1 867 GLU n 1 868 TRP n 1 869 ALA n 1 870 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'MGAM, MGA, MGAML' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id ? _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id ? _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable Transfection Plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMT-BiP-V5-His _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MGA_HUMAN _struct_ref.pdbx_db_accession O43451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW ; _struct_ref.pdbx_align_begin 87 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3CTT _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 868 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O43451 _struct_ref_seq.db_align_beg 87 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 954 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 868 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3CTT ALA A 869 ? UNP O43451 ? ? 'EXPRESSION TAG' 869 1 1 3CTT HIS A 870 ? UNP O43451 ? ? 'EXPRESSION TAG' 870 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 3CU non-polymer . CASUARINE '(1R,2R,3R,6S,7S,7aR)-3-(hydroxymethyl)hexahydro-1H-pyrrolizine-1,2,6,7-tetrol' 'C8 H15 N O5' 205.208 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3CTT _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.63 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 53.15 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details '20% PEG 3350, 0.2M sodium sulfate, 4% 1,1,1,3,3,3-hexafluoro-2-propanol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2007-05-19 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9175 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9175 _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 # _reflns.entry_id 3CTT _reflns.d_resolution_high 2.100 _reflns.d_resolution_low 20.000 _reflns.number_obs 58131 _reflns.pdbx_Rmerge_I_obs 0.118 _reflns.pdbx_netI_over_sigmaI 11.900 _reflns.pdbx_chi_squared 1.036 _reflns.percent_possible_obs 95.600 _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.number_all ? _reflns.pdbx_Rsym_value ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 6.3 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.10 _reflns_shell.d_res_low 2.15 _reflns_shell.number_measured_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_unique_obs ? _reflns_shell.Rmerge_I_obs 0.432 _reflns_shell.meanI_over_sigI_obs 4.96 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared 0.937 _reflns_shell.pdbx_redundancy 5.5 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 3891 _reflns_shell.percent_possible_all 97.40 _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3CTT _refine.ls_d_res_high 2.100 _refine.ls_d_res_low 15.650 _refine.pdbx_ls_sigma_F 0.00 _refine.ls_percent_reflns_obs 94.590 _refine.ls_number_reflns_obs 57768 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.ls_R_factor_obs 0.228 _refine.ls_R_factor_R_work 0.225 _refine.ls_R_factor_R_free 0.278 _refine.ls_percent_reflns_R_free 5.100 _refine.ls_number_reflns_R_free 2932 _refine.B_iso_mean 22.542 _refine.aniso_B[1][1] 0.060 _refine.aniso_B[2][2] -0.020 _refine.aniso_B[3][3] -0.030 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc 0.901 _refine.correlation_coeff_Fo_to_Fc_free 0.865 _refine.pdbx_overall_ESU_R 0.263 _refine.pdbx_overall_ESU_R_Free 0.222 _refine.overall_SU_ML 0.138 _refine.overall_SU_B 4.969 _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.400 _refine.pdbx_solvent_ion_probe_radii 0.800 _refine.pdbx_solvent_shrinkage_radii 0.800 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all ? _refine.ls_R_factor_all ? _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_starting_model 'PDB entry 2QMJ' _refine.pdbx_stereochem_target_val_spec_case ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_isotropic_thermal_model ? _refine.details ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6905 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 101 _refine_hist.number_atoms_solvent 352 _refine_hist.number_atoms_total 7358 _refine_hist.d_res_high 2.100 _refine_hist.d_res_low 15.650 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 7200 0.014 0.022 ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 9810 1.527 1.946 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 860 6.843 5.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 363 35.313 24.325 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 1091 14.431 15.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 38 17.846 15.000 ? 'X-RAY DIFFRACTION' ? r_chiral_restr 1047 0.106 0.200 ? 'X-RAY DIFFRACTION' ? r_gen_planes_refined 5607 0.006 0.020 ? 'X-RAY DIFFRACTION' ? r_nbd_refined 3530 0.213 0.200 ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 4846 0.313 0.200 ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 519 0.164 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 82 0.214 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 12 0.133 0.200 ? 'X-RAY DIFFRACTION' ? r_mcbond_it 4411 0.866 1.500 ? 'X-RAY DIFFRACTION' ? r_mcangle_it 6967 1.413 2.000 ? 'X-RAY DIFFRACTION' ? r_scbond_it 3228 2.224 3.000 ? 'X-RAY DIFFRACTION' ? r_scangle_it 2843 3.275 4.500 ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 2.100 _refine_ls_shell.d_res_low 2.154 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 95.970 _refine_ls_shell.number_reflns_R_work 4012 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.259 _refine_ls_shell.R_factor_R_free 0.359 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 207 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.number_reflns_all 4219 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3CTT _struct.title 'Crystal complex of N-terminal Human Maltase-Glucoamylase with Casuarine' _struct.pdbx_descriptor 'Maltase-glucoamylase (E.C.3.2.1.20)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3CTT _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text ;Glycosyl Hydrolase Family 31, alpha-glucosidase, Glycoprotein, Glycosidase, Membrane, Multifunctional enzyme, Signal-anchor, Sulfation, Transmembrane, HYDROLASE ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 4 ? F N N 5 ? G N N 5 ? H N N 5 ? I N N 5 ? J N N 5 ? K N N 5 ? L N N 5 ? M N N 5 ? N N N 5 ? O N N 6 ? # _struct_biol.id 1 _struct_biol.details Monomer # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 8 ? ARG A 12 ? ASN A 8 ARG A 12 5 ? 5 HELX_P HELX_P2 2 THR A 22 ? ARG A 29 ? THR A 22 ARG A 29 1 ? 8 HELX_P HELX_P3 3 SER A 155 ? GLY A 157 ? SER A 155 GLY A 157 5 ? 3 HELX_P HELX_P4 4 THR A 269 ? GLY A 282 ? THR A 269 GLY A 282 1 ? 14 HELX_P HELX_P5 5 SER A 288 ? LEU A 292 ? SER A 288 LEU A 292 5 ? 5 HELX_P HELX_P6 6 THR A 303 ? ALA A 317 ? THR A 303 ALA A 317 1 ? 15 HELX_P HELX_P7 7 ASP A 327 ? MET A 331 ? ASP A 327 MET A 331 5 ? 5 HELX_P HELX_P8 8 GLY A 346 ? ASN A 357 ? GLY A 346 ASN A 357 1 ? 12 HELX_P HELX_P9 9 TYR A 379 ? LYS A 389 ? TYR A 379 LYS A 389 1 ? 11 HELX_P HELX_P10 10 ASN A 417 ? ASN A 433 ? ASN A 417 ASN A 433 1 ? 17 HELX_P HELX_P11 11 ILE A 472 ? TYR A 476 ? ILE A 472 TYR A 476 5 ? 5 HELX_P HELX_P12 12 GLN A 493 ? HIS A 497 ? GLN A 493 HIS A 497 1 ? 5 HELX_P HELX_P13 13 LEU A 499 ? PHE A 516 ? LEU A 499 PHE A 516 1 ? 18 HELX_P HELX_P14 14 GLY A 531 ? PHE A 535 ? GLY A 531 PHE A 535 5 ? 5 HELX_P HELX_P15 15 THR A 546 ? PHE A 563 ? THR A 546 PHE A 563 1 ? 18 HELX_P HELX_P16 16 PRO A 580 ? ALA A 592 ? PRO A 580 ALA A 592 1 ? 13 HELX_P HELX_P17 17 ASP A 609 ? GLY A 614 ? ASP A 609 GLY A 614 5 ? 6 HELX_P HELX_P18 18 SER A 617 ? LEU A 633 ? SER A 617 LEU A 633 1 ? 17 HELX_P HELX_P19 19 LEU A 633 ? ARG A 647 ? LEU A 633 ARG A 647 1 ? 15 HELX_P HELX_P20 20 LEU A 655 ? TYR A 660 ? LEU A 655 TYR A 660 1 ? 6 HELX_P HELX_P21 21 ASP A 662 ? TRP A 666 ? ASP A 662 TRP A 666 5 ? 5 HELX_P HELX_P22 22 THR A 743 ? ARG A 748 ? THR A 743 ARG A 748 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 31 SG ? ? A CYS 15 A CYS 31 1_555 ? ? ? ? ? ? ? 2.063 ? disulf2 disulf ? ? A CYS 573 SG ? ? ? 1_555 A CYS 584 SG ? ? A CYS 573 A CYS 584 1_555 ? ? ? ? ? ? ? 2.062 ? covale1 covale ? ? A ASN 393 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 393 A NAG 2002 1_555 ? ? ? ? ? ? ? 1.456 ? covale2 covale ? ? A ASN 741 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 741 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.455 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLN 136 A . ? GLN 136 A PRO 137 A ? PRO 137 A 1 2.31 2 GLY 181 A . ? GLY 181 A GLU 182 A ? GLU 182 A 1 -0.67 3 ALA 248 A . ? ALA 248 A PRO 249 A ? PRO 249 A 1 -4.56 4 GLU 446 A . ? GLU 446 A VAL 447 A ? VAL 447 A 1 1.79 5 PRO 835 A . ? PRO 835 A SER 836 A ? SER 836 A 1 -10.14 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 8 ? C ? 3 ? D ? 5 ? E ? 9 ? F ? 3 ? G ? 2 ? H ? 5 ? I ? 2 ? J ? 10 ? K ? 9 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? parallel E 5 6 ? parallel E 6 7 ? parallel E 7 8 ? parallel E 8 9 ? parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? parallel J 6 7 ? anti-parallel J 7 8 ? parallel J 8 9 ? anti-parallel J 9 10 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel K 5 6 ? parallel K 6 7 ? anti-parallel K 7 8 ? parallel K 8 9 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 CYS A 32 ? TRP A 33 ? CYS A 32 TRP A 33 A 2 CYS A 44 ? TYR A 45 ? CYS A 44 TYR A 45 B 1 TYR A 52 ? ASN A 60 ? TYR A 52 ASN A 60 B 2 GLY A 64 ? ASN A 71 ? GLY A 64 ASN A 71 B 3 ASN A 84 ? THR A 93 ? ASN A 84 THR A 93 B 4 ARG A 96 ? ASP A 103 ? ARG A 96 ASP A 103 B 5 LEU A 260 ? GLY A 267 ? LEU A 260 GLY A 267 B 6 SER A 230 ? LEU A 235 ? SER A 230 LEU A 235 B 7 GLN A 217 ? LEU A 223 ? GLN A 217 LEU A 223 B 8 VAL A 177 ? GLY A 181 ? VAL A 177 GLY A 181 C 1 TYR A 129 ? SER A 134 ? TYR A 129 SER A 134 C 2 SER A 139 ? ARG A 144 ? SER A 139 ARG A 144 C 3 VAL A 150 ? ASP A 153 ? VAL A 150 ASP A 153 D 1 LEU A 160 ? ALA A 162 ? LEU A 160 ALA A 162 D 2 PHE A 165 ? ARG A 171 ? PHE A 165 ARG A 171 D 3 ALA A 250 ? THR A 255 ? ALA A 250 THR A 255 D 4 MET A 241 ? GLN A 246 ? MET A 241 GLN A 246 D 5 LYS A 195 ? ILE A 199 ? LYS A 195 ILE A 199 E 1 VAL A 568 ? GLY A 569 ? VAL A 568 GLY A 569 E 2 ALA A 537 ? TRP A 539 ? ALA A 537 TRP A 539 E 3 ILE A 523 ? THR A 525 ? ILE A 523 THR A 525 E 4 GLY A 439 ? ILE A 442 ? GLY A 439 ILE A 442 E 5 LYS A 360 ? VAL A 365 ? LYS A 360 VAL A 365 E 6 VAL A 323 ? ALA A 326 ? VAL A 323 ALA A 326 E 7 PHE A 294 ? LEU A 296 ? PHE A 294 LEU A 296 E 8 SER A 597 ? ASN A 599 ? SER A 597 ASN A 599 E 9 ASP A 571 ? ILE A 572 ? ASP A 571 ILE A 572 F 1 ILE A 369 ? SER A 370 ? ILE A 369 SER A 370 F 2 GLY A 408 ? VAL A 411 ? GLY A 408 VAL A 411 F 3 GLY A 403 ? VAL A 405 ? GLY A 403 VAL A 405 G 1 VAL A 487 ? GLN A 488 ? VAL A 487 GLN A 488 G 2 GLY A 491 ? LYS A 492 ? GLY A 491 LYS A 492 H 1 ALA A 652 ? ARG A 653 ? ALA A 652 ARG A 653 H 2 PHE A 672 ? TRP A 674 ? PHE A 672 TRP A 674 H 3 LEU A 678 ? THR A 681 ? LEU A 678 THR A 681 H 4 GLY A 726 ? ARG A 730 ? GLY A 726 ARG A 730 H 5 TRP A 700 ? ASP A 702 ? TRP A 700 ASP A 702 I 1 LYS A 690 ? VAL A 695 ? LYS A 690 VAL A 695 I 2 GLN A 714 ? GLU A 719 ? GLN A 714 GLU A 719 J 1 SER A 825 ? LYS A 830 ? SER A 825 LYS A 830 J 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 J 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 J 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 J 5 GLU A 763 ? TRP A 770 ? GLU A 763 TRP A 770 J 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 J 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 J 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 J 9 VAL A 850 ? THR A 854 ? VAL A 850 THR A 854 J 10 THR A 841 ? ASP A 845 ? THR A 841 ASP A 845 K 1 SER A 825 ? LYS A 830 ? SER A 825 LYS A 830 K 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 K 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 K 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 K 5 GLU A 763 ? TRP A 770 ? GLU A 763 TRP A 770 K 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 K 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 K 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 K 9 LEU A 858 ? LEU A 859 ? LEU A 858 LEU A 859 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N CYS A 32 ? N CYS A 32 O TYR A 45 ? O TYR A 45 B 1 2 N GLU A 55 ? N GLU A 55 O ARG A 68 ? O ARG A 68 B 2 3 N LEU A 69 ? N LEU A 69 O VAL A 85 ? O VAL A 85 B 3 4 N GLU A 90 ? N GLU A 90 O HIS A 98 ? O HIS A 98 B 4 5 N PHE A 99 ? N PHE A 99 O PHE A 262 ? O PHE A 262 B 5 6 O PHE A 265 ? O PHE A 265 N GLY A 232 ? N GLY A 232 B 6 7 O PHE A 231 ? O PHE A 231 N CYS A 222 ? N CYS A 222 B 7 8 O PHE A 219 ? O PHE A 219 N LEU A 180 ? N LEU A 180 C 1 2 N GLN A 130 ? N GLN A 130 O THR A 143 ? O THR A 143 C 2 3 N VAL A 142 ? N VAL A 142 O PHE A 152 ? O PHE A 152 D 1 2 N ALA A 162 ? N ALA A 162 O PHE A 165 ? O PHE A 165 D 2 3 N LEU A 166 ? N LEU A 166 O THR A 255 ? O THR A 255 D 3 4 O THR A 252 ? O THR A 252 N VAL A 244 ? N VAL A 244 D 4 5 O LEU A 245 ? O LEU A 245 N LYS A 195 ? N LYS A 195 E 1 2 O GLY A 569 ? O GLY A 569 N HIS A 538 ? N HIS A 538 E 2 3 O ALA A 537 ? O ALA A 537 N THR A 525 ? N THR A 525 E 3 4 O LEU A 524 ? O LEU A 524 N ILE A 442 ? N ILE A 442 E 4 5 O TRP A 441 ? O TRP A 441 N ILE A 363 ? N ILE A 363 E 5 6 O VAL A 362 ? O VAL A 362 N ALA A 326 ? N ALA A 326 E 6 7 O HIS A 325 ? O HIS A 325 N LEU A 296 ? N LEU A 296 E 7 8 N HIS A 295 ? N HIS A 295 O SER A 597 ? O SER A 597 E 8 9 O ARG A 598 ? O ARG A 598 N ILE A 572 ? N ILE A 572 F 1 2 N ILE A 369 ? N ILE A 369 O VAL A 411 ? O VAL A 411 F 2 3 O THR A 410 ? O THR A 410 N GLY A 403 ? N GLY A 403 G 1 2 N GLN A 488 ? N GLN A 488 O GLY A 491 ? O GLY A 491 H 1 2 N ARG A 653 ? N ARG A 653 O LEU A 673 ? O LEU A 673 H 2 3 N PHE A 672 ? N PHE A 672 O ILE A 680 ? O ILE A 680 H 3 4 N LEU A 679 ? N LEU A 679 O HIS A 728 ? O HIS A 728 H 4 5 O LEU A 729 ? O LEU A 729 N TYR A 701 ? N TYR A 701 I 1 2 N VAL A 691 ? N VAL A 691 O MET A 718 ? O MET A 718 J 1 2 N LYS A 830 ? N LYS A 830 O THR A 865 ? O THR A 865 J 2 3 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 J 3 4 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 J 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 J 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 J 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 J 7 8 N ILE A 756 ? N ILE A 756 O LEU A 819 ? O LEU A 819 J 8 9 N ILE A 816 ? N ILE A 816 O ILE A 853 ? O ILE A 853 J 9 10 O THR A 854 ? O THR A 854 N THR A 841 ? N THR A 841 K 1 2 N LYS A 830 ? N LYS A 830 O THR A 865 ? O THR A 865 K 2 3 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 K 3 4 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 K 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 K 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 K 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 K 7 8 N ILE A 756 ? N ILE A 756 O LEU A 819 ? O LEU A 819 K 8 9 N PHE A 813 ? N PHE A 813 O LEU A 858 ? O LEU A 858 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE NAG A 2001' AC2 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG A 2002' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 A 4001' AC4 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE 3CU A 1001' AC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3001' AC6 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 3002' AC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GOL A 3003' AC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3004' AC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3005' BC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3006' BC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3007' BC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3008' BC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3009' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 9 SER A 146 ? SER A 146 . ? 2_454 ? 2 AC1 9 ASN A 147 ? ASN A 147 . ? 2_454 ? 3 AC1 9 ASN A 148 ? ASN A 148 . ? 2_454 ? 4 AC1 9 ASN A 741 ? ASN A 741 . ? 1_555 ? 5 AC1 9 ALA A 746 ? ALA A 746 . ? 1_555 ? 6 AC1 9 ASN A 750 ? ASN A 750 . ? 1_555 ? 7 AC1 9 HOH O . ? HOH A 4101 . ? 1_555 ? 8 AC1 9 HOH O . ? HOH A 4221 . ? 2_454 ? 9 AC1 9 HOH O . ? HOH A 4282 . ? 1_555 ? 10 AC2 7 LYS A 389 ? LYS A 389 . ? 1_555 ? 11 AC2 7 ASN A 393 ? ASN A 393 . ? 1_555 ? 12 AC2 7 GLY A 397 ? GLY A 397 . ? 1_555 ? 13 AC2 7 GLN A 488 ? GLN A 488 . ? 1_555 ? 14 AC2 7 HIS A 489 ? HIS A 489 . ? 1_555 ? 15 AC2 7 HOH O . ? HOH A 4184 . ? 1_555 ? 16 AC2 7 HOH O . ? HOH A 4273 . ? 1_555 ? 17 AC3 5 SER A 126 ? SER A 126 . ? 2_454 ? 18 AC3 5 ARG A 145 ? ARG A 145 . ? 2_454 ? 19 AC3 5 HIS A 625 ? HIS A 625 . ? 1_555 ? 20 AC3 5 ASN A 628 ? ASN A 628 . ? 1_555 ? 21 AC3 5 HOH O . ? HOH A 4069 . ? 1_555 ? 22 AC4 11 TYR A 299 ? TYR A 299 . ? 1_555 ? 23 AC4 11 ASP A 327 ? ASP A 327 . ? 1_555 ? 24 AC4 11 ILE A 364 ? ILE A 364 . ? 1_555 ? 25 AC4 11 TRP A 441 ? TRP A 441 . ? 1_555 ? 26 AC4 11 ASP A 443 ? ASP A 443 . ? 1_555 ? 27 AC4 11 ARG A 526 ? ARG A 526 . ? 1_555 ? 28 AC4 11 TRP A 539 ? TRP A 539 . ? 1_555 ? 29 AC4 11 ASP A 542 ? ASP A 542 . ? 1_555 ? 30 AC4 11 PHE A 575 ? PHE A 575 . ? 1_555 ? 31 AC4 11 HIS A 600 ? HIS A 600 . ? 1_555 ? 32 AC4 11 HOH O . ? HOH A 4353 . ? 1_555 ? 33 AC5 4 ASP A 203 ? ASP A 203 . ? 1_555 ? 34 AC5 4 ARG A 526 ? ARG A 526 . ? 1_555 ? 35 AC5 4 ASP A 542 ? ASP A 542 . ? 1_555 ? 36 AC5 4 HOH O . ? HOH A 4265 . ? 1_555 ? 37 AC6 8 ALA A 285 ? ALA A 285 . ? 1_555 ? 38 AC6 8 PRO A 287 ? PRO A 287 . ? 1_555 ? 39 AC6 8 PHE A 522 ? PHE A 522 . ? 1_555 ? 40 AC6 8 ILE A 523 ? ILE A 523 . ? 1_555 ? 41 AC6 8 PHE A 535 ? PHE A 535 . ? 1_555 ? 42 AC6 8 ALA A 536 ? ALA A 536 . ? 1_555 ? 43 AC6 8 ALA A 537 ? ALA A 537 . ? 1_555 ? 44 AC6 8 HOH O . ? HOH A 4117 . ? 1_555 ? 45 AC7 6 ASN A 306 ? ASN A 306 . ? 1_555 ? 46 AC7 6 GLU A 309 ? GLU A 309 . ? 1_555 ? 47 AC7 6 ARG A 313 ? ARG A 313 . ? 1_555 ? 48 AC7 6 ASP A 607 ? ASP A 607 . ? 1_555 ? 49 AC7 6 HOH O . ? HOH A 4056 . ? 1_555 ? 50 AC7 6 HOH O . ? HOH A 4237 . ? 1_555 ? 51 AC8 5 LEU A 58 ? LEU A 58 . ? 1_555 ? 52 AC8 5 GLU A 132 ? GLU A 132 . ? 1_555 ? 53 AC8 5 ILE A 133 ? ILE A 133 . ? 1_555 ? 54 AC8 5 THR A 843 ? THR A 843 . ? 2_455 ? 55 AC8 5 THR A 854 ? THR A 854 . ? 2_455 ? 56 AC9 4 ASP A 153 ? ASP A 153 . ? 1_555 ? 57 AC9 4 ARG A 171 ? ARG A 171 . ? 1_555 ? 58 AC9 4 HOH O . ? HOH A 4169 . ? 1_555 ? 59 AC9 4 HOH O . ? HOH A 4313 . ? 1_555 ? 60 BC1 5 ALA A 24 ? ALA A 24 . ? 3_555 ? 61 BC1 5 GLU A 312 ? GLU A 312 . ? 1_555 ? 62 BC1 5 GLU A 353 ? GLU A 353 . ? 1_555 ? 63 BC1 5 HOH O . ? HOH A 4145 . ? 1_555 ? 64 BC1 5 HOH O . ? HOH A 4232 . ? 3_555 ? 65 BC2 4 ASP A 772 ? ASP A 772 . ? 1_555 ? 66 BC2 4 THR A 775 ? THR A 775 . ? 1_555 ? 67 BC2 4 THR A 778 ? THR A 778 . ? 1_555 ? 68 BC2 4 HOH O . ? HOH A 4010 . ? 1_555 ? 69 BC3 4 ARG A 145 ? ARG A 145 . ? 2_454 ? 70 BC3 4 GLN A 739 ? GLN A 739 . ? 1_555 ? 71 BC3 4 PRO A 740 ? PRO A 740 . ? 1_555 ? 72 BC3 4 HOH O . ? HOH A 4275 . ? 2_454 ? 73 BC4 5 GLN A 130 ? GLN A 130 . ? 1_555 ? 74 BC4 5 GLU A 132 ? GLU A 132 . ? 1_555 ? 75 BC4 5 ASN A 814 ? ASN A 814 . ? 2_455 ? 76 BC4 5 THR A 854 ? THR A 854 . ? 2_455 ? 77 BC4 5 ASP A 855 ? ASP A 855 . ? 2_455 ? # _atom_sites.entry_id 3CTT _atom_sites.fract_transf_matrix[1][1] 0.011535 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009163 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.009138 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 7 ? -12.891 -36.819 63.371 1.00 36.61 ? 7 VAL A N 1 ATOM 2 C CA . VAL A 1 7 ? -12.698 -35.868 62.230 1.00 36.68 ? 7 VAL A CA 1 ATOM 3 C C . VAL A 1 7 ? -13.675 -36.252 61.113 1.00 35.83 ? 7 VAL A C 1 ATOM 4 O O . VAL A 1 7 ? -13.525 -37.299 60.477 1.00 36.66 ? 7 VAL A O 1 ATOM 5 C CB . VAL A 1 7 ? -11.212 -35.873 61.686 1.00 36.72 ? 7 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 7 ? -10.977 -34.742 60.684 1.00 37.32 ? 7 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 7 ? -10.220 -35.734 62.802 1.00 37.16 ? 7 VAL A CG2 1 ATOM 8 N N . ASN A 1 8 ? -14.696 -35.423 60.898 1.00 34.56 ? 8 ASN A N 1 ATOM 9 C CA . ASN A 1 8 ? -15.486 -35.489 59.671 1.00 32.30 ? 8 ASN A CA 1 ATOM 10 C C . ASN A 1 8 ? -14.488 -35.601 58.507 1.00 30.82 ? 8 ASN A C 1 ATOM 11 O O . ASN A 1 8 ? -13.516 -34.847 58.441 1.00 30.30 ? 8 ASN A O 1 ATOM 12 C CB . ASN A 1 8 ? -16.380 -34.241 59.596 1.00 32.83 ? 8 ASN A CB 1 ATOM 13 C CG . ASN A 1 8 ? -16.890 -33.908 58.174 1.00 33.99 ? 8 ASN A CG 1 ATOM 14 O OD1 . ASN A 1 8 ? -16.883 -34.738 57.251 1.00 34.69 ? 8 ASN A OD1 1 ATOM 15 N ND2 . ASN A 1 8 ? -17.362 -32.666 58.014 1.00 35.67 ? 8 ASN A ND2 1 ATOM 16 N N . GLU A 1 9 ? -14.694 -36.583 57.634 1.00 28.87 ? 9 GLU A N 1 ATOM 17 C CA . GLU A 1 9 ? -13.795 -36.814 56.498 1.00 28.08 ? 9 GLU A CA 1 ATOM 18 C C . GLU A 1 9 ? -13.613 -35.625 55.509 1.00 26.14 ? 9 GLU A C 1 ATOM 19 O O . GLU A 1 9 ? -12.575 -35.531 54.869 1.00 25.95 ? 9 GLU A O 1 ATOM 20 C CB . GLU A 1 9 ? -14.100 -38.148 55.795 1.00 28.43 ? 9 GLU A CB 1 ATOM 21 C CG . GLU A 1 9 ? -15.435 -38.290 55.116 1.00 29.72 ? 9 GLU A CG 1 ATOM 22 C CD . GLU A 1 9 ? -15.607 -39.671 54.468 1.00 31.14 ? 9 GLU A CD 1 ATOM 23 O OE1 . GLU A 1 9 ? -15.548 -40.711 55.176 1.00 34.68 ? 9 GLU A OE1 1 ATOM 24 O OE2 . GLU A 1 9 ? -15.829 -39.723 53.234 1.00 34.79 ? 9 GLU A OE2 1 ATOM 25 N N . LEU A 1 10 ? -14.583 -34.705 55.432 1.00 23.42 ? 10 LEU A N 1 ATOM 26 C CA . LEU A 1 10 ? -14.463 -33.505 54.590 1.00 22.02 ? 10 LEU A CA 1 ATOM 27 C C . LEU A 1 10 ? -13.471 -32.519 55.168 1.00 20.83 ? 10 LEU A C 1 ATOM 28 O O . LEU A 1 10 ? -13.008 -31.641 54.461 1.00 20.40 ? 10 LEU A O 1 ATOM 29 C CB . LEU A 1 10 ? -15.825 -32.802 54.375 1.00 21.45 ? 10 LEU A CB 1 ATOM 30 C CG . LEU A 1 10 ? -16.923 -33.697 53.804 1.00 23.24 ? 10 LEU A CG 1 ATOM 31 C CD1 . LEU A 1 10 ? -18.254 -32.949 53.546 1.00 23.72 ? 10 LEU A CD1 1 ATOM 32 C CD2 . LEU A 1 10 ? -16.464 -34.433 52.559 1.00 23.45 ? 10 LEU A CD2 1 ATOM 33 N N . GLU A 1 11 ? -13.152 -32.681 56.453 1.00 20.13 ? 11 GLU A N 1 ATOM 34 C CA . GLU A 1 11 ? -12.265 -31.791 57.156 1.00 21.50 ? 11 GLU A CA 1 ATOM 35 C C . GLU A 1 11 ? -10.822 -32.315 57.244 1.00 19.96 ? 11 GLU A C 1 ATOM 36 O O . GLU A 1 11 ? -9.948 -31.624 57.773 1.00 19.54 ? 11 GLU A O 1 ATOM 37 C CB . GLU A 1 11 ? -12.803 -31.473 58.553 1.00 21.03 ? 11 GLU A CB 1 ATOM 38 C CG . GLU A 1 11 ? -14.091 -30.682 58.573 1.00 24.99 ? 11 GLU A CG 1 ATOM 39 C CD . GLU A 1 11 ? -14.625 -30.473 59.986 1.00 26.49 ? 11 GLU A CD 1 ATOM 40 O OE1 . GLU A 1 11 ? -13.851 -30.606 60.966 1.00 32.48 ? 11 GLU A OE1 1 ATOM 41 O OE2 . GLU A 1 11 ? -15.833 -30.168 60.116 1.00 33.21 ? 11 GLU A OE2 1 ATOM 42 N N . ARG A 1 12 ? -10.580 -33.511 56.702 1.00 19.04 ? 12 ARG A N 1 ATOM 43 C CA . ARG A 1 12 ? -9.232 -34.104 56.680 1.00 19.29 ? 12 ARG A CA 1 ATOM 44 C C . ARG A 1 12 ? -8.282 -33.308 55.802 1.00 18.02 ? 12 ARG A C 1 ATOM 45 O O . ARG A 1 12 ? -8.623 -32.959 54.687 1.00 18.44 ? 12 ARG A O 1 ATOM 46 C CB . ARG A 1 12 ? -9.290 -35.549 56.187 1.00 19.23 ? 12 ARG A CB 1 ATOM 47 C CG . ARG A 1 12 ? -9.869 -36.542 57.169 1.00 20.84 ? 12 ARG A CG 1 ATOM 48 C CD . ARG A 1 12 ? -9.905 -37.874 56.495 1.00 23.97 ? 12 ARG A CD 1 ATOM 49 N NE . ARG A 1 12 ? -10.792 -38.835 57.117 1.00 29.17 ? 12 ARG A NE 1 ATOM 50 C CZ . ARG A 1 12 ? -10.834 -40.123 56.769 1.00 30.15 ? 12 ARG A CZ 1 ATOM 51 N NH1 . ARG A 1 12 ? -10.014 -40.618 55.811 1.00 25.49 ? 12 ARG A NH1 1 ATOM 52 N NH2 . ARG A 1 12 ? -11.703 -40.906 57.378 1.00 30.43 ? 12 ARG A NH2 1 ATOM 53 N N . ILE A 1 13 ? -7.094 -33.031 56.314 1.00 17.44 ? 13 ILE A N 1 ATOM 54 C CA . ILE A 1 13 ? -6.079 -32.262 55.593 1.00 16.21 ? 13 ILE A CA 1 ATOM 55 C C . ILE A 1 13 ? -4.982 -33.261 55.195 1.00 16.70 ? 13 ILE A C 1 ATOM 56 O O . ILE A 1 13 ? -4.316 -33.832 56.058 1.00 15.89 ? 13 ILE A O 1 ATOM 57 C CB . ILE A 1 13 ? -5.530 -31.073 56.443 1.00 15.95 ? 13 ILE A CB 1 ATOM 58 C CG1 . ILE A 1 13 ? -6.667 -30.117 56.872 1.00 15.59 ? 13 ILE A CG1 1 ATOM 59 C CG2 . ILE A 1 13 ? -4.419 -30.294 55.704 1.00 16.02 ? 13 ILE A CG2 1 ATOM 60 C CD1 . ILE A 1 13 ? -7.211 -29.249 55.729 1.00 16.08 ? 13 ILE A CD1 1 ATOM 61 N N . ASN A 1 14 ? -4.830 -33.459 53.886 1.00 16.16 ? 14 ASN A N 1 ATOM 62 C CA . ASN A 1 14 ? -4.000 -34.495 53.318 1.00 17.20 ? 14 ASN A CA 1 ATOM 63 C C . ASN A 1 14 ? -2.540 -34.273 53.736 1.00 17.27 ? 14 ASN A C 1 ATOM 64 O O . ASN A 1 14 ? -1.965 -33.211 53.486 1.00 15.94 ? 14 ASN A O 1 ATOM 65 C CB . ASN A 1 14 ? -4.120 -34.469 51.793 1.00 16.96 ? 14 ASN A CB 1 ATOM 66 C CG . ASN A 1 14 ? -3.278 -35.564 51.087 1.00 18.08 ? 14 ASN A CG 1 ATOM 67 O OD1 . ASN A 1 14 ? -2.826 -36.519 51.705 1.00 16.15 ? 14 ASN A OD1 1 ATOM 68 N ND2 . ASN A 1 14 ? -3.083 -35.406 49.774 1.00 17.89 ? 14 ASN A ND2 1 ATOM 69 N N . CYS A 1 15 ? -1.993 -35.303 54.367 1.00 18.95 ? 15 CYS A N 1 ATOM 70 C CA . CYS A 1 15 ? -0.613 -35.369 54.850 1.00 19.77 ? 15 CYS A CA 1 ATOM 71 C C . CYS A 1 15 ? 0.317 -36.015 53.829 1.00 20.49 ? 15 CYS A C 1 ATOM 72 O O . CYS A 1 15 ? 1.571 -36.008 54.006 1.00 20.06 ? 15 CYS A O 1 ATOM 73 C CB . CYS A 1 15 ? -0.590 -36.155 56.190 1.00 19.84 ? 15 CYS A CB 1 ATOM 74 S SG . CYS A 1 15 ? 1.071 -36.543 56.828 1.00 22.46 ? 15 CYS A SG 1 ATOM 75 N N . ILE A 1 16 ? -0.278 -36.597 52.776 1.00 19.95 ? 16 ILE A N 1 ATOM 76 C CA . ILE A 1 16 ? 0.512 -37.173 51.665 1.00 20.28 ? 16 ILE A CA 1 ATOM 77 C C . ILE A 1 16 ? 0.108 -36.577 50.289 1.00 21.64 ? 16 ILE A C 1 ATOM 78 O O . ILE A 1 16 ? -0.557 -37.258 49.485 1.00 21.65 ? 16 ILE A O 1 ATOM 79 C CB . ILE A 1 16 ? 0.465 -38.759 51.620 1.00 19.69 ? 16 ILE A CB 1 ATOM 80 C CG1 . ILE A 1 16 ? 0.893 -39.381 52.955 1.00 19.42 ? 16 ILE A CG1 1 ATOM 81 C CG2 . ILE A 1 16 ? 1.401 -39.278 50.555 1.00 19.66 ? 16 ILE A CG2 1 ATOM 82 C CD1 . ILE A 1 16 ? 0.786 -40.910 53.036 1.00 18.34 ? 16 ILE A CD1 1 ATOM 83 N N . PRO A 1 17 ? 0.518 -35.323 50.006 1.00 22.81 ? 17 PRO A N 1 ATOM 84 C CA . PRO A 1 17 ? 0.187 -34.646 48.736 1.00 24.45 ? 17 PRO A CA 1 ATOM 85 C C . PRO A 1 17 ? 1.100 -35.028 47.578 1.00 25.70 ? 17 PRO A C 1 ATOM 86 O O . PRO A 1 17 ? 0.797 -34.710 46.423 1.00 26.49 ? 17 PRO A O 1 ATOM 87 C CB . PRO A 1 17 ? 0.435 -33.178 49.073 1.00 24.35 ? 17 PRO A CB 1 ATOM 88 C CG . PRO A 1 17 ? 1.512 -33.202 50.070 1.00 23.09 ? 17 PRO A CG 1 ATOM 89 C CD . PRO A 1 17 ? 1.310 -34.445 50.885 1.00 23.30 ? 17 PRO A CD 1 ATOM 90 N N . ASP A 1 18 ? 2.192 -35.719 47.915 1.00 26.00 ? 18 ASP A N 1 ATOM 91 C CA . ASP A 1 18 ? 3.351 -35.946 47.052 1.00 27.05 ? 18 ASP A CA 1 ATOM 92 C C . ASP A 1 18 ? 3.431 -37.337 46.427 1.00 27.19 ? 18 ASP A C 1 ATOM 93 O O . ASP A 1 18 ? 4.290 -37.585 45.578 1.00 27.38 ? 18 ASP A O 1 ATOM 94 C CB . ASP A 1 18 ? 4.644 -35.684 47.850 1.00 26.36 ? 18 ASP A CB 1 ATOM 95 C CG . ASP A 1 18 ? 4.671 -36.392 49.235 1.00 28.29 ? 18 ASP A CG 1 ATOM 96 O OD1 . ASP A 1 18 ? 3.663 -36.395 49.995 1.00 27.64 ? 18 ASP A OD1 1 ATOM 97 O OD2 . ASP A 1 18 ? 5.734 -36.945 49.589 1.00 29.15 ? 18 ASP A OD2 1 ATOM 98 N N . GLN A 1 19 ? 2.556 -38.248 46.845 1.00 27.38 ? 19 GLN A N 1 ATOM 99 C CA . GLN A 1 19 ? 2.632 -39.633 46.383 1.00 27.77 ? 19 GLN A CA 1 ATOM 100 C C . GLN A 1 19 ? 1.321 -40.394 46.603 1.00 27.46 ? 19 GLN A C 1 ATOM 101 O O . GLN A 1 19 ? 0.451 -39.900 47.311 1.00 27.26 ? 19 GLN A O 1 ATOM 102 C CB . GLN A 1 19 ? 3.829 -40.346 47.043 1.00 27.61 ? 19 GLN A CB 1 ATOM 103 C CG . GLN A 1 19 ? 3.709 -40.608 48.517 1.00 27.30 ? 19 GLN A CG 1 ATOM 104 C CD . GLN A 1 19 ? 5.042 -40.883 49.202 1.00 28.04 ? 19 GLN A CD 1 ATOM 105 O OE1 . GLN A 1 19 ? 6.083 -40.390 48.779 1.00 31.42 ? 19 GLN A OE1 1 ATOM 106 N NE2 . GLN A 1 19 ? 5.009 -41.664 50.277 1.00 24.21 ? 19 GLN A NE2 1 ATOM 107 N N . PRO A 1 20 ? 1.160 -41.585 45.966 1.00 27.33 ? 20 PRO A N 1 ATOM 108 C CA . PRO A 1 20 ? 0.048 -42.460 46.379 1.00 26.56 ? 20 PRO A CA 1 ATOM 109 C C . PRO A 1 20 ? 0.146 -42.816 47.880 1.00 25.24 ? 20 PRO A C 1 ATOM 110 O O . PRO A 1 20 ? 1.221 -43.179 48.342 1.00 24.33 ? 20 PRO A O 1 ATOM 111 C CB . PRO A 1 20 ? 0.211 -43.701 45.492 1.00 26.34 ? 20 PRO A CB 1 ATOM 112 C CG . PRO A 1 20 ? 1.630 -43.639 44.962 1.00 27.24 ? 20 PRO A CG 1 ATOM 113 C CD . PRO A 1 20 ? 1.936 -42.176 44.853 1.00 27.78 ? 20 PRO A CD 1 ATOM 114 N N . PRO A 1 21 ? -0.969 -42.659 48.634 1.00 24.26 ? 21 PRO A N 1 ATOM 115 C CA . PRO A 1 21 ? -0.984 -42.778 50.103 1.00 23.90 ? 21 PRO A CA 1 ATOM 116 C C . PRO A 1 21 ? -0.648 -44.186 50.610 1.00 23.45 ? 21 PRO A C 1 ATOM 117 O O . PRO A 1 21 ? -1.253 -45.160 50.157 1.00 24.15 ? 21 PRO A O 1 ATOM 118 C CB . PRO A 1 21 ? -2.429 -42.407 50.482 1.00 23.35 ? 21 PRO A CB 1 ATOM 119 C CG . PRO A 1 21 ? -3.226 -42.599 49.248 1.00 25.23 ? 21 PRO A CG 1 ATOM 120 C CD . PRO A 1 21 ? -2.291 -42.308 48.094 1.00 24.73 ? 21 PRO A CD 1 ATOM 121 N N . THR A 1 22 ? 0.314 -44.307 51.522 1.00 22.46 ? 22 THR A N 1 ATOM 122 C CA . THR A 1 22 ? 0.544 -45.604 52.171 1.00 21.26 ? 22 THR A CA 1 ATOM 123 C C . THR A 1 22 ? 0.554 -45.457 53.679 1.00 21.46 ? 22 THR A C 1 ATOM 124 O O . THR A 1 22 ? 0.887 -44.395 54.182 1.00 21.49 ? 22 THR A O 1 ATOM 125 C CB . THR A 1 22 ? 1.880 -46.259 51.740 1.00 20.69 ? 22 THR A CB 1 ATOM 126 O OG1 . THR A 1 22 ? 2.959 -45.411 52.123 1.00 20.35 ? 22 THR A OG1 1 ATOM 127 C CG2 . THR A 1 22 ? 1.916 -46.476 50.244 1.00 19.53 ? 22 THR A CG2 1 ATOM 128 N N . LYS A 1 23 ? 0.209 -46.527 54.391 1.00 21.55 ? 23 LYS A N 1 ATOM 129 C CA . LYS A 1 23 ? 0.296 -46.533 55.841 1.00 22.74 ? 23 LYS A CA 1 ATOM 130 C C . LYS A 1 23 ? 1.740 -46.348 56.343 1.00 22.78 ? 23 LYS A C 1 ATOM 131 O O . LYS A 1 23 ? 1.956 -45.637 57.302 1.00 22.91 ? 23 LYS A O 1 ATOM 132 C CB . LYS A 1 23 ? -0.351 -47.795 56.448 1.00 23.57 ? 23 LYS A CB 1 ATOM 133 C CG . LYS A 1 23 ? -0.552 -47.678 57.975 1.00 24.92 ? 23 LYS A CG 1 ATOM 134 C CD . LYS A 1 23 ? -1.061 -48.943 58.617 1.00 24.65 ? 23 LYS A CD 1 ATOM 135 C CE . LYS A 1 23 ? -1.400 -48.710 60.110 1.00 27.44 ? 23 LYS A CE 1 ATOM 136 N NZ . LYS A 1 23 ? -0.219 -48.372 60.983 1.00 29.12 ? 23 LYS A NZ 1 ATOM 137 N N . ALA A 1 24 ? 2.728 -46.941 55.677 1.00 22.92 ? 24 ALA A N 1 ATOM 138 C CA . ALA A 1 24 ? 4.129 -46.752 56.072 1.00 23.23 ? 24 ALA A CA 1 ATOM 139 C C . ALA A 1 24 ? 4.597 -45.290 56.005 1.00 23.22 ? 24 ALA A C 1 ATOM 140 O O . ALA A 1 24 ? 5.236 -44.793 56.921 1.00 24.08 ? 24 ALA A O 1 ATOM 141 C CB . ALA A 1 24 ? 5.053 -47.670 55.236 1.00 23.68 ? 24 ALA A CB 1 ATOM 142 N N . THR A 1 25 ? 4.304 -44.596 54.916 1.00 22.91 ? 25 THR A N 1 ATOM 143 C CA . THR A 1 25 ? 4.611 -43.177 54.864 1.00 22.81 ? 25 THR A CA 1 ATOM 144 C C . THR A 1 25 ? 3.751 -42.418 55.892 1.00 22.54 ? 25 THR A C 1 ATOM 145 O O . THR A 1 25 ? 4.211 -41.502 56.551 1.00 21.02 ? 25 THR A O 1 ATOM 146 C CB . THR A 1 25 ? 4.361 -42.622 53.466 1.00 23.36 ? 25 THR A CB 1 ATOM 147 O OG1 . THR A 1 25 ? 5.259 -43.240 52.537 1.00 22.86 ? 25 THR A OG1 1 ATOM 148 C CG2 . THR A 1 25 ? 4.564 -41.134 53.441 1.00 22.93 ? 25 THR A CG2 1 ATOM 149 N N . CYS A 1 26 ? 2.489 -42.806 56.008 1.00 23.75 ? 26 CYS A N 1 ATOM 150 C CA . CYS A 1 26 ? 1.623 -42.188 56.985 1.00 24.18 ? 26 CYS A CA 1 ATOM 151 C C . CYS A 1 26 ? 2.213 -42.253 58.400 1.00 24.13 ? 26 CYS A C 1 ATOM 152 O O . CYS A 1 26 ? 2.270 -41.244 59.089 1.00 24.31 ? 26 CYS A O 1 ATOM 153 C CB . CYS A 1 26 ? 0.253 -42.845 56.969 1.00 24.23 ? 26 CYS A CB 1 ATOM 154 S SG . CYS A 1 26 ? -0.799 -42.132 58.268 1.00 27.94 ? 26 CYS A SG 1 ATOM 155 N N . ASP A 1 27 ? 2.646 -43.445 58.816 1.00 24.40 ? 27 ASP A N 1 ATOM 156 C CA . ASP A 1 27 ? 3.226 -43.669 60.145 1.00 24.83 ? 27 ASP A CA 1 ATOM 157 C C . ASP A 1 27 ? 4.558 -42.919 60.328 1.00 24.87 ? 27 ASP A C 1 ATOM 158 O O . ASP A 1 27 ? 4.797 -42.351 61.390 1.00 25.12 ? 27 ASP A O 1 ATOM 159 C CB . ASP A 1 27 ? 3.405 -45.165 60.408 1.00 24.99 ? 27 ASP A CB 1 ATOM 160 C CG . ASP A 1 27 ? 2.075 -45.905 60.562 1.00 27.60 ? 27 ASP A CG 1 ATOM 161 O OD1 . ASP A 1 27 ? 0.999 -45.270 60.659 1.00 30.45 ? 27 ASP A OD1 1 ATOM 162 O OD2 . ASP A 1 27 ? 2.106 -47.146 60.591 1.00 31.52 ? 27 ASP A OD2 1 ATOM 163 N N . GLN A 1 28 ? 5.391 -42.879 59.291 1.00 24.26 ? 28 GLN A N 1 ATOM 164 C CA . GLN A 1 28 ? 6.683 -42.161 59.367 1.00 25.15 ? 28 GLN A CA 1 ATOM 165 C C . GLN A 1 28 ? 6.491 -40.657 59.597 1.00 24.87 ? 28 GLN A C 1 ATOM 166 O O . GLN A 1 28 ? 7.285 -40.011 60.299 1.00 24.48 ? 28 GLN A O 1 ATOM 167 C CB . GLN A 1 28 ? 7.551 -42.440 58.119 1.00 25.24 ? 28 GLN A CB 1 ATOM 168 C CG . GLN A 1 28 ? 8.829 -41.592 58.002 1.00 27.51 ? 28 GLN A CG 1 ATOM 169 C CD . GLN A 1 28 ? 9.755 -41.718 59.224 1.00 31.60 ? 28 GLN A CD 1 ATOM 170 O OE1 . GLN A 1 28 ? 10.252 -40.717 59.748 1.00 35.42 ? 28 GLN A OE1 1 ATOM 171 N NE2 . GLN A 1 28 ? 9.973 -42.941 59.682 1.00 32.35 ? 28 GLN A NE2 1 ATOM 172 N N . ARG A 1 29 ? 5.417 -40.113 59.027 1.00 24.73 ? 29 ARG A N 1 ATOM 173 C CA . ARG A 1 29 ? 5.110 -38.692 59.160 1.00 24.56 ? 29 ARG A CA 1 ATOM 174 C C . ARG A 1 29 ? 4.292 -38.339 60.391 1.00 24.04 ? 29 ARG A C 1 ATOM 175 O O . ARG A 1 29 ? 4.045 -37.171 60.635 1.00 23.85 ? 29 ARG A O 1 ATOM 176 C CB . ARG A 1 29 ? 4.399 -38.178 57.896 1.00 25.37 ? 29 ARG A CB 1 ATOM 177 C CG . ARG A 1 29 ? 5.285 -38.280 56.667 1.00 25.02 ? 29 ARG A CG 1 ATOM 178 C CD . ARG A 1 29 ? 4.608 -37.760 55.420 1.00 26.53 ? 29 ARG A CD 1 ATOM 179 N NE . ARG A 1 29 ? 5.475 -38.036 54.276 1.00 23.51 ? 29 ARG A NE 1 ATOM 180 C CZ . ARG A 1 29 ? 5.179 -37.755 53.021 1.00 23.23 ? 29 ARG A CZ 1 ATOM 181 N NH1 . ARG A 1 29 ? 4.028 -37.160 52.711 1.00 18.81 ? 29 ARG A NH1 1 ATOM 182 N NH2 . ARG A 1 29 ? 6.042 -38.074 52.078 1.00 22.10 ? 29 ARG A NH2 1 ATOM 183 N N . GLY A 1 30 ? 3.872 -39.341 61.158 1.00 23.70 ? 30 GLY A N 1 ATOM 184 C CA . GLY A 1 30 ? 3.090 -39.113 62.360 1.00 23.12 ? 30 GLY A CA 1 ATOM 185 C C . GLY A 1 30 ? 1.665 -38.653 62.054 1.00 23.60 ? 30 GLY A C 1 ATOM 186 O O . GLY A 1 30 ? 1.101 -37.859 62.790 1.00 23.71 ? 30 GLY A O 1 ATOM 187 N N . CYS A 1 31 ? 1.075 -39.158 60.979 1.00 23.07 ? 31 CYS A N 1 ATOM 188 C CA . CYS A 1 31 ? -0.263 -38.688 60.560 1.00 23.35 ? 31 CYS A CA 1 ATOM 189 C C . CYS A 1 31 ? -1.327 -39.748 60.826 1.00 23.04 ? 31 CYS A C 1 ATOM 190 O O . CYS A 1 31 ? -1.025 -40.764 61.424 1.00 23.26 ? 31 CYS A O 1 ATOM 191 C CB . CYS A 1 31 ? -0.219 -38.229 59.098 1.00 23.12 ? 31 CYS A CB 1 ATOM 192 S SG . CYS A 1 31 ? 0.791 -36.694 58.866 1.00 24.45 ? 31 CYS A SG 1 ATOM 193 N N . CYS A 1 32 ? -2.568 -39.514 60.407 1.00 23.78 ? 32 CYS A N 1 ATOM 194 C CA . CYS A 1 32 ? -3.675 -40.426 60.718 1.00 24.04 ? 32 CYS A CA 1 ATOM 195 C C . CYS A 1 32 ? -4.053 -41.240 59.496 1.00 23.83 ? 32 CYS A C 1 ATOM 196 O O . CYS A 1 32 ? -4.068 -40.718 58.387 1.00 23.36 ? 32 CYS A O 1 ATOM 197 C CB . CYS A 1 32 ? -4.898 -39.644 61.170 1.00 24.46 ? 32 CYS A CB 1 ATOM 198 S SG . CYS A 1 32 ? -4.639 -38.638 62.607 1.00 26.55 ? 32 CYS A SG 1 ATOM 199 N N . TRP A 1 33 ? -4.378 -42.510 59.699 1.00 23.57 ? 33 TRP A N 1 ATOM 200 C CA . TRP A 1 33 ? -4.659 -43.412 58.595 1.00 24.49 ? 33 TRP A CA 1 ATOM 201 C C . TRP A 1 33 ? -6.099 -43.920 58.680 1.00 25.37 ? 33 TRP A C 1 ATOM 202 O O . TRP A 1 33 ? -6.514 -44.447 59.707 1.00 24.55 ? 33 TRP A O 1 ATOM 203 C CB . TRP A 1 33 ? -3.674 -44.582 58.618 1.00 23.77 ? 33 TRP A CB 1 ATOM 204 C CG . TRP A 1 33 ? -3.831 -45.546 57.498 1.00 23.79 ? 33 TRP A CG 1 ATOM 205 C CD1 . TRP A 1 33 ? -4.360 -46.811 57.561 1.00 23.63 ? 33 TRP A CD1 1 ATOM 206 C CD2 . TRP A 1 33 ? -3.464 -45.331 56.124 1.00 23.85 ? 33 TRP A CD2 1 ATOM 207 N NE1 . TRP A 1 33 ? -4.335 -47.393 56.313 1.00 23.16 ? 33 TRP A NE1 1 ATOM 208 C CE2 . TRP A 1 33 ? -3.790 -46.508 55.416 1.00 23.12 ? 33 TRP A CE2 1 ATOM 209 C CE3 . TRP A 1 33 ? -2.870 -44.261 55.429 1.00 22.19 ? 33 TRP A CE3 1 ATOM 210 C CZ2 . TRP A 1 33 ? -3.549 -46.647 54.050 1.00 23.08 ? 33 TRP A CZ2 1 ATOM 211 C CZ3 . TRP A 1 33 ? -2.628 -44.407 54.078 1.00 23.38 ? 33 TRP A CZ3 1 ATOM 212 C CH2 . TRP A 1 33 ? -2.974 -45.593 53.403 1.00 22.98 ? 33 TRP A CH2 1 ATOM 213 N N . ASN A 1 34 ? -6.853 -43.715 57.606 1.00 26.90 ? 34 ASN A N 1 ATOM 214 C CA . ASN A 1 34 ? -8.230 -44.198 57.492 1.00 28.70 ? 34 ASN A CA 1 ATOM 215 C C . ASN A 1 34 ? -8.589 -44.292 56.017 1.00 30.37 ? 34 ASN A C 1 ATOM 216 O O . ASN A 1 34 ? -9.056 -43.317 55.427 1.00 30.26 ? 34 ASN A O 1 ATOM 217 C CB . ASN A 1 34 ? -9.202 -43.291 58.258 1.00 28.34 ? 34 ASN A CB 1 ATOM 218 C CG . ASN A 1 34 ? -10.665 -43.800 58.225 1.00 30.37 ? 34 ASN A CG 1 ATOM 219 O OD1 . ASN A 1 34 ? -11.023 -44.676 57.444 1.00 32.50 ? 34 ASN A OD1 1 ATOM 220 N ND2 . ASN A 1 34 ? -11.497 -43.245 59.088 1.00 27.86 ? 34 ASN A ND2 1 ATOM 221 N N . PRO A 1 35 ? -8.322 -45.456 55.390 1.00 32.44 ? 35 PRO A N 1 ATOM 222 C CA . PRO A 1 35 ? -8.652 -45.602 53.974 1.00 34.04 ? 35 PRO A CA 1 ATOM 223 C C . PRO A 1 35 ? -10.141 -45.716 53.644 1.00 35.97 ? 35 PRO A C 1 ATOM 224 O O . PRO A 1 35 ? -10.461 -45.991 52.495 1.00 37.81 ? 35 PRO A O 1 ATOM 225 C CB . PRO A 1 35 ? -7.931 -46.900 53.563 1.00 33.66 ? 35 PRO A CB 1 ATOM 226 C CG . PRO A 1 35 ? -7.034 -47.243 54.696 1.00 33.07 ? 35 PRO A CG 1 ATOM 227 C CD . PRO A 1 35 ? -7.647 -46.655 55.912 1.00 32.69 ? 35 PRO A CD 1 ATOM 228 N N . GLN A 1 36 ? -11.041 -45.507 54.596 1.00 37.92 ? 36 GLN A N 1 ATOM 229 C CA . GLN A 1 36 ? -12.477 -45.751 54.331 1.00 40.55 ? 36 GLN A CA 1 ATOM 230 C C . GLN A 1 36 ? -13.376 -44.511 54.042 1.00 41.09 ? 36 GLN A C 1 ATOM 231 O O . GLN A 1 36 ? -14.599 -44.552 54.264 1.00 42.07 ? 36 GLN A O 1 ATOM 232 C CB . GLN A 1 36 ? -13.091 -46.644 55.429 1.00 41.18 ? 36 GLN A CB 1 ATOM 233 C CG . GLN A 1 36 ? -12.305 -47.941 55.752 1.00 43.67 ? 36 GLN A CG 1 ATOM 234 C CD . GLN A 1 36 ? -12.400 -49.029 54.672 1.00 47.33 ? 36 GLN A CD 1 ATOM 235 O OE1 . GLN A 1 36 ? -13.037 -48.851 53.628 1.00 47.90 ? 36 GLN A OE1 1 ATOM 236 N NE2 . GLN A 1 36 ? -11.750 -50.167 54.927 1.00 49.05 ? 36 GLN A NE2 1 ATOM 237 N N . GLY A 1 37 ? -12.791 -43.425 53.539 1.00 40.98 ? 37 GLY A N 1 ATOM 238 C CA . GLY A 1 37 ? -13.599 -42.298 53.042 1.00 40.77 ? 37 GLY A CA 1 ATOM 239 C C . GLY A 1 37 ? -14.048 -42.504 51.597 1.00 40.63 ? 37 GLY A C 1 ATOM 240 O O . GLY A 1 37 ? -13.735 -43.543 50.984 1.00 41.53 ? 37 GLY A O 1 ATOM 241 N N . ALA A 1 38 ? -14.777 -41.526 51.041 1.00 39.60 ? 38 ALA A N 1 ATOM 242 C CA . ALA A 1 38 ? -15.182 -41.545 49.619 1.00 38.26 ? 38 ALA A CA 1 ATOM 243 C C . ALA A 1 38 ? -14.022 -41.139 48.694 1.00 37.35 ? 38 ALA A C 1 ATOM 244 O O . ALA A 1 38 ? -12.908 -40.896 49.163 1.00 37.13 ? 38 ALA A O 1 ATOM 245 C CB . ALA A 1 38 ? -16.363 -40.621 49.405 1.00 38.34 ? 38 ALA A CB 1 ATOM 246 N N . VAL A 1 39 ? -14.287 -41.057 47.389 1.00 35.63 ? 39 VAL A N 1 ATOM 247 C CA . VAL A 1 39 ? -13.265 -40.644 46.408 1.00 33.91 ? 39 VAL A CA 1 ATOM 248 C C . VAL A 1 39 ? -12.615 -39.295 46.748 1.00 32.68 ? 39 VAL A C 1 ATOM 249 O O . VAL A 1 39 ? -13.308 -38.322 47.064 1.00 32.05 ? 39 VAL A O 1 ATOM 250 C CB . VAL A 1 39 ? -13.793 -40.659 44.932 1.00 33.97 ? 39 VAL A CB 1 ATOM 251 C CG1 . VAL A 1 39 ? -14.850 -39.593 44.682 1.00 33.95 ? 39 VAL A CG1 1 ATOM 252 C CG2 . VAL A 1 39 ? -12.641 -40.521 43.946 1.00 34.13 ? 39 VAL A CG2 1 ATOM 253 N N . SER A 1 40 ? -11.281 -39.280 46.715 1.00 30.84 ? 40 SER A N 1 ATOM 254 C CA . SER A 1 40 ? -10.466 -38.069 46.950 1.00 29.57 ? 40 SER A CA 1 ATOM 255 C C . SER A 1 40 ? -10.334 -37.714 48.432 1.00 27.45 ? 40 SER A C 1 ATOM 256 O O . SER A 1 40 ? -9.483 -36.918 48.784 1.00 26.99 ? 40 SER A O 1 ATOM 257 C CB . SER A 1 40 ? -10.972 -36.851 46.151 1.00 29.35 ? 40 SER A CB 1 ATOM 258 O OG . SER A 1 40 ? -11.072 -37.108 44.757 1.00 30.70 ? 40 SER A OG 1 ATOM 259 N N . VAL A 1 41 ? -11.158 -38.303 49.295 1.00 25.77 ? 41 VAL A N 1 ATOM 260 C CA . VAL A 1 41 ? -10.968 -38.141 50.749 1.00 25.10 ? 41 VAL A CA 1 ATOM 261 C C . VAL A 1 41 ? -9.573 -38.706 51.116 1.00 24.16 ? 41 VAL A C 1 ATOM 262 O O . VAL A 1 41 ? -9.277 -39.850 50.790 1.00 24.33 ? 41 VAL A O 1 ATOM 263 C CB . VAL A 1 41 ? -12.089 -38.816 51.567 1.00 24.90 ? 41 VAL A CB 1 ATOM 264 C CG1 . VAL A 1 41 ? -11.767 -38.788 53.071 1.00 24.98 ? 41 VAL A CG1 1 ATOM 265 C CG2 . VAL A 1 41 ? -13.396 -38.126 51.331 1.00 24.99 ? 41 VAL A CG2 1 ATOM 266 N N . PRO A 1 42 ? -8.700 -37.895 51.750 1.00 23.58 ? 42 PRO A N 1 ATOM 267 C CA . PRO A 1 42 ? -7.328 -38.363 51.976 1.00 22.93 ? 42 PRO A CA 1 ATOM 268 C C . PRO A 1 42 ? -7.277 -39.545 52.928 1.00 22.80 ? 42 PRO A C 1 ATOM 269 O O . PRO A 1 42 ? -7.868 -39.508 54.009 1.00 22.90 ? 42 PRO A O 1 ATOM 270 C CB . PRO A 1 42 ? -6.645 -37.160 52.642 1.00 23.47 ? 42 PRO A CB 1 ATOM 271 C CG . PRO A 1 42 ? -7.535 -36.040 52.466 1.00 22.27 ? 42 PRO A CG 1 ATOM 272 C CD . PRO A 1 42 ? -8.903 -36.543 52.286 1.00 22.93 ? 42 PRO A CD 1 ATOM 273 N N . TRP A 1 43 ? -6.554 -40.587 52.534 1.00 22.55 ? 43 TRP A N 1 ATOM 274 C CA . TRP A 1 43 ? -6.400 -41.761 53.372 1.00 21.99 ? 43 TRP A CA 1 ATOM 275 C C . TRP A 1 43 ? -5.486 -41.410 54.542 1.00 21.56 ? 43 TRP A C 1 ATOM 276 O O . TRP A 1 43 ? -5.591 -41.969 55.617 1.00 21.25 ? 43 TRP A O 1 ATOM 277 C CB . TRP A 1 43 ? -5.797 -42.894 52.536 1.00 23.20 ? 43 TRP A CB 1 ATOM 278 C CG . TRP A 1 43 ? -6.771 -43.534 51.625 1.00 23.37 ? 43 TRP A CG 1 ATOM 279 C CD1 . TRP A 1 43 ? -8.051 -43.126 51.381 1.00 24.49 ? 43 TRP A CD1 1 ATOM 280 C CD2 . TRP A 1 43 ? -6.559 -44.696 50.812 1.00 25.42 ? 43 TRP A CD2 1 ATOM 281 N NE1 . TRP A 1 43 ? -8.647 -43.957 50.482 1.00 25.09 ? 43 TRP A NE1 1 ATOM 282 C CE2 . TRP A 1 43 ? -7.761 -44.932 50.109 1.00 24.00 ? 43 TRP A CE2 1 ATOM 283 C CE3 . TRP A 1 43 ? -5.473 -45.563 50.614 1.00 24.96 ? 43 TRP A CE3 1 ATOM 284 C CZ2 . TRP A 1 43 ? -7.919 -45.997 49.219 1.00 24.32 ? 43 TRP A CZ2 1 ATOM 285 C CZ3 . TRP A 1 43 ? -5.619 -46.622 49.719 1.00 25.53 ? 43 TRP A CZ3 1 ATOM 286 C CH2 . TRP A 1 43 ? -6.853 -46.837 49.044 1.00 25.87 ? 43 TRP A CH2 1 ATOM 287 N N . CYS A 1 44 ? -4.580 -40.477 54.301 1.00 21.19 ? 44 CYS A N 1 ATOM 288 C CA . CYS A 1 44 ? -3.610 -40.055 55.298 1.00 20.84 ? 44 CYS A CA 1 ATOM 289 C C . CYS A 1 44 ? -3.747 -38.543 55.548 1.00 20.45 ? 44 CYS A C 1 ATOM 290 O O . CYS A 1 44 ? -3.594 -37.732 54.638 1.00 19.92 ? 44 CYS A O 1 ATOM 291 C CB . CYS A 1 44 ? -2.209 -40.424 54.849 1.00 20.23 ? 44 CYS A CB 1 ATOM 292 S SG . CYS A 1 44 ? -0.974 -39.813 55.983 1.00 22.68 ? 44 CYS A SG 1 ATOM 293 N N . TYR A 1 45 ? -4.063 -38.178 56.781 1.00 20.71 ? 45 TYR A N 1 ATOM 294 C CA . TYR A 1 45 ? -4.366 -36.791 57.121 1.00 20.80 ? 45 TYR A CA 1 ATOM 295 C C . TYR A 1 45 ? -3.672 -36.377 58.404 1.00 20.63 ? 45 TYR A C 1 ATOM 296 O O . TYR A 1 45 ? -3.238 -37.223 59.176 1.00 19.96 ? 45 TYR A O 1 ATOM 297 C CB . TYR A 1 45 ? -5.899 -36.543 57.175 1.00 20.78 ? 45 TYR A CB 1 ATOM 298 C CG . TYR A 1 45 ? -6.640 -37.441 58.133 1.00 21.89 ? 45 TYR A CG 1 ATOM 299 C CD1 . TYR A 1 45 ? -7.020 -36.984 59.396 1.00 20.27 ? 45 TYR A CD1 1 ATOM 300 C CD2 . TYR A 1 45 ? -6.976 -38.754 57.776 1.00 20.94 ? 45 TYR A CD2 1 ATOM 301 C CE1 . TYR A 1 45 ? -7.703 -37.814 60.279 1.00 21.46 ? 45 TYR A CE1 1 ATOM 302 C CE2 . TYR A 1 45 ? -7.633 -39.594 58.663 1.00 20.51 ? 45 TYR A CE2 1 ATOM 303 C CZ . TYR A 1 45 ? -7.993 -39.124 59.904 1.00 21.78 ? 45 TYR A CZ 1 ATOM 304 O OH . TYR A 1 45 ? -8.665 -39.960 60.769 1.00 25.05 ? 45 TYR A OH 1 ATOM 305 N N . TYR A 1 46 ? -3.518 -35.078 58.620 1.00 21.15 ? 46 TYR A N 1 ATOM 306 C CA . TYR A 1 46 ? -2.767 -34.626 59.780 1.00 23.36 ? 46 TYR A CA 1 ATOM 307 C C . TYR A 1 46 ? -3.535 -34.879 61.054 1.00 25.11 ? 46 TYR A C 1 ATOM 308 O O . TYR A 1 46 ? -4.769 -34.809 61.065 1.00 24.28 ? 46 TYR A O 1 ATOM 309 C CB . TYR A 1 46 ? -2.386 -33.146 59.690 1.00 22.51 ? 46 TYR A CB 1 ATOM 310 C CG . TYR A 1 46 ? -1.374 -32.869 58.619 1.00 21.00 ? 46 TYR A CG 1 ATOM 311 C CD1 . TYR A 1 46 ? -0.006 -33.149 58.827 1.00 18.25 ? 46 TYR A CD1 1 ATOM 312 C CD2 . TYR A 1 46 ? -1.765 -32.325 57.396 1.00 17.52 ? 46 TYR A CD2 1 ATOM 313 C CE1 . TYR A 1 46 ? 0.926 -32.894 57.826 1.00 19.33 ? 46 TYR A CE1 1 ATOM 314 C CE2 . TYR A 1 46 ? -0.833 -32.058 56.396 1.00 17.30 ? 46 TYR A CE2 1 ATOM 315 C CZ . TYR A 1 46 ? 0.513 -32.356 56.621 1.00 20.96 ? 46 TYR A CZ 1 ATOM 316 O OH . TYR A 1 46 ? 1.453 -32.119 55.634 1.00 23.14 ? 46 TYR A OH 1 ATOM 317 N N . SER A 1 47 ? -2.780 -35.205 62.105 1.00 27.92 ? 47 SER A N 1 ATOM 318 C CA . SER A 1 47 ? -3.307 -35.381 63.469 1.00 30.96 ? 47 SER A CA 1 ATOM 319 C C . SER A 1 47 ? -3.599 -34.029 64.102 1.00 33.66 ? 47 SER A C 1 ATOM 320 O O . SER A 1 47 ? -3.084 -33.008 63.636 1.00 33.88 ? 47 SER A O 1 ATOM 321 C CB . SER A 1 47 ? -2.309 -36.148 64.325 1.00 30.31 ? 47 SER A CB 1 ATOM 322 O OG . SER A 1 47 ? -1.086 -35.440 64.407 1.00 30.15 ? 47 SER A OG 1 ATOM 323 N N . LYS A 1 48 ? -4.397 -34.044 65.178 1.00 37.22 ? 48 LYS A N 1 ATOM 324 C CA . LYS A 1 48 ? -5.014 -32.839 65.777 1.00 40.67 ? 48 LYS A CA 1 ATOM 325 C C . LYS A 1 48 ? -4.052 -31.946 66.552 1.00 41.80 ? 48 LYS A C 1 ATOM 326 O O . LYS A 1 48 ? -4.398 -30.818 66.938 1.00 42.69 ? 48 LYS A O 1 ATOM 327 C CB . LYS A 1 48 ? -6.224 -33.207 66.658 1.00 40.56 ? 48 LYS A CB 1 ATOM 328 C CG . LYS A 1 48 ? -7.539 -33.351 65.884 1.00 42.06 ? 48 LYS A CG 1 ATOM 329 C CD . LYS A 1 48 ? -8.672 -33.903 66.768 1.00 42.77 ? 48 LYS A CD 1 ATOM 330 C CE . LYS A 1 48 ? -9.682 -32.825 67.206 1.00 45.70 ? 48 LYS A CE 1 ATOM 331 N NZ . LYS A 1 48 ? -10.992 -32.852 66.439 1.00 46.28 ? 48 LYS A NZ 1 ATOM 332 N N . ASN A 1 49 ? -2.845 -32.450 66.759 1.00 43.15 ? 49 ASN A N 1 ATOM 333 C CA . ASN A 1 49 ? -1.828 -31.736 67.486 1.00 44.45 ? 49 ASN A CA 1 ATOM 334 C C . ASN A 1 49 ? -0.510 -32.236 66.919 1.00 44.84 ? 49 ASN A C 1 ATOM 335 O O . ASN A 1 49 ? -0.229 -33.433 66.912 1.00 45.58 ? 49 ASN A O 1 ATOM 336 C CB . ASN A 1 49 ? -1.966 -32.003 68.996 1.00 45.16 ? 49 ASN A CB 1 ATOM 337 C CG . ASN A 1 49 ? -1.720 -30.754 69.852 1.00 46.50 ? 49 ASN A CG 1 ATOM 338 O OD1 . ASN A 1 49 ? -0.672 -30.102 69.747 1.00 48.81 ? 49 ASN A OD1 1 ATOM 339 N ND2 . ASN A 1 49 ? -2.680 -30.434 70.726 1.00 46.92 ? 49 ASN A ND2 1 ATOM 340 N N . HIS A 1 50 ? 0.297 -31.278 66.487 1.00 45.20 ? 50 HIS A N 1 ATOM 341 C CA . HIS A 1 50 ? 1.287 -31.391 65.412 1.00 44.82 ? 50 HIS A CA 1 ATOM 342 C C . HIS A 1 50 ? 1.327 -29.904 65.071 1.00 43.77 ? 50 HIS A C 1 ATOM 343 O O . HIS A 1 50 ? 0.367 -29.164 65.392 1.00 44.64 ? 50 HIS A O 1 ATOM 344 C CB . HIS A 1 50 ? 0.739 -32.201 64.207 1.00 45.56 ? 50 HIS A CB 1 ATOM 345 C CG . HIS A 1 50 ? 1.620 -32.206 62.972 1.00 47.76 ? 50 HIS A CG 1 ATOM 346 N ND1 . HIS A 1 50 ? 2.120 -33.372 62.418 1.00 48.77 ? 50 HIS A ND1 1 ATOM 347 C CD2 . HIS A 1 50 ? 2.051 -31.201 62.166 1.00 48.59 ? 50 HIS A CD2 1 ATOM 348 C CE1 . HIS A 1 50 ? 2.842 -33.082 61.347 1.00 48.83 ? 50 HIS A CE1 1 ATOM 349 N NE2 . HIS A 1 50 ? 2.820 -31.772 61.174 1.00 49.31 ? 50 HIS A NE2 1 ATOM 350 N N . SER A 1 51 ? 2.416 -29.467 64.446 1.00 41.15 ? 51 SER A N 1 ATOM 351 C CA . SER A 1 51 ? 2.605 -28.083 63.996 1.00 38.38 ? 51 SER A CA 1 ATOM 352 C C . SER A 1 51 ? 3.290 -27.222 65.055 1.00 35.84 ? 51 SER A C 1 ATOM 353 O O . SER A 1 51 ? 4.274 -27.636 65.664 1.00 36.86 ? 51 SER A O 1 ATOM 354 C CB . SER A 1 51 ? 1.310 -27.439 63.432 1.00 38.61 ? 51 SER A CB 1 ATOM 355 O OG . SER A 1 51 ? 0.382 -27.106 64.436 1.00 38.57 ? 51 SER A OG 1 ATOM 356 N N . TYR A 1 52 ? 2.795 -26.014 65.252 1.00 32.19 ? 52 TYR A N 1 ATOM 357 C CA . TYR A 1 52 ? 3.495 -25.051 66.065 1.00 28.38 ? 52 TYR A CA 1 ATOM 358 C C . TYR A 1 52 ? 2.728 -24.740 67.335 1.00 27.44 ? 52 TYR A C 1 ATOM 359 O O . TYR A 1 52 ? 1.518 -24.969 67.417 1.00 26.54 ? 52 TYR A O 1 ATOM 360 C CB . TYR A 1 52 ? 3.725 -23.803 65.230 1.00 27.07 ? 52 TYR A CB 1 ATOM 361 C CG . TYR A 1 52 ? 4.832 -23.977 64.217 1.00 25.47 ? 52 TYR A CG 1 ATOM 362 C CD1 . TYR A 1 52 ? 4.616 -24.650 63.008 1.00 22.24 ? 52 TYR A CD1 1 ATOM 363 C CD2 . TYR A 1 52 ? 6.108 -23.478 64.475 1.00 23.56 ? 52 TYR A CD2 1 ATOM 364 C CE1 . TYR A 1 52 ? 5.658 -24.817 62.069 1.00 23.00 ? 52 TYR A CE1 1 ATOM 365 C CE2 . TYR A 1 52 ? 7.138 -23.638 63.547 1.00 23.80 ? 52 TYR A CE2 1 ATOM 366 C CZ . TYR A 1 52 ? 6.908 -24.308 62.363 1.00 23.23 ? 52 TYR A CZ 1 ATOM 367 O OH . TYR A 1 52 ? 7.946 -24.426 61.483 1.00 25.30 ? 52 TYR A OH 1 ATOM 368 N N . HIS A 1 53 ? 3.440 -24.255 68.342 1.00 26.43 ? 53 HIS A N 1 ATOM 369 C CA . HIS A 1 53 ? 2.771 -23.718 69.526 1.00 26.29 ? 53 HIS A CA 1 ATOM 370 C C . HIS A 1 53 ? 3.273 -22.316 69.785 1.00 25.26 ? 53 HIS A C 1 ATOM 371 O O . HIS A 1 53 ? 4.407 -21.977 69.430 1.00 24.78 ? 53 HIS A O 1 ATOM 372 C CB . HIS A 1 53 ? 2.911 -24.651 70.754 1.00 26.99 ? 53 HIS A CB 1 ATOM 373 C CG . HIS A 1 53 ? 4.316 -24.839 71.220 1.00 28.27 ? 53 HIS A CG 1 ATOM 374 N ND1 . HIS A 1 53 ? 4.844 -24.145 72.287 1.00 33.47 ? 53 HIS A ND1 1 ATOM 375 C CD2 . HIS A 1 53 ? 5.315 -25.622 70.751 1.00 30.89 ? 53 HIS A CD2 1 ATOM 376 C CE1 . HIS A 1 53 ? 6.106 -24.497 72.461 1.00 31.53 ? 53 HIS A CE1 1 ATOM 377 N NE2 . HIS A 1 53 ? 6.419 -25.391 71.539 1.00 31.31 ? 53 HIS A NE2 1 ATOM 378 N N . VAL A 1 54 ? 2.414 -21.484 70.364 1.00 24.82 ? 54 VAL A N 1 ATOM 379 C CA . VAL A 1 54 ? 2.822 -20.147 70.759 1.00 24.16 ? 54 VAL A CA 1 ATOM 380 C C . VAL A 1 54 ? 3.758 -20.343 71.947 1.00 24.72 ? 54 VAL A C 1 ATOM 381 O O . VAL A 1 54 ? 3.431 -21.079 72.874 1.00 24.91 ? 54 VAL A O 1 ATOM 382 C CB . VAL A 1 54 ? 1.609 -19.234 71.148 1.00 24.04 ? 54 VAL A CB 1 ATOM 383 C CG1 . VAL A 1 54 ? 2.092 -17.903 71.641 1.00 22.78 ? 54 VAL A CG1 1 ATOM 384 C CG2 . VAL A 1 54 ? 0.626 -19.012 69.943 1.00 22.06 ? 54 VAL A CG2 1 ATOM 385 N N . GLU A 1 55 ? 4.935 -19.726 71.896 1.00 24.98 ? 55 GLU A N 1 ATOM 386 C CA . GLU A 1 55 ? 5.803 -19.707 73.044 1.00 25.74 ? 55 GLU A CA 1 ATOM 387 C C . GLU A 1 55 ? 5.669 -18.358 73.775 1.00 24.79 ? 55 GLU A C 1 ATOM 388 O O . GLU A 1 55 ? 5.914 -17.295 73.189 1.00 24.91 ? 55 GLU A O 1 ATOM 389 C CB . GLU A 1 55 ? 7.251 -19.974 72.613 1.00 27.04 ? 55 GLU A CB 1 ATOM 390 C CG . GLU A 1 55 ? 8.219 -20.242 73.773 1.00 32.32 ? 55 GLU A CG 1 ATOM 391 C CD . GLU A 1 55 ? 7.956 -21.551 74.499 1.00 37.05 ? 55 GLU A CD 1 ATOM 392 O OE1 . GLU A 1 55 ? 8.242 -22.631 73.931 1.00 40.44 ? 55 GLU A OE1 1 ATOM 393 O OE2 . GLU A 1 55 ? 7.484 -21.500 75.659 1.00 40.08 ? 55 GLU A OE2 1 ATOM 394 N N . GLY A 1 56 ? 5.274 -18.396 75.045 1.00 22.92 ? 56 GLY A N 1 ATOM 395 C CA . GLY A 1 56 ? 5.245 -17.183 75.861 1.00 22.86 ? 56 GLY A CA 1 ATOM 396 C C . GLY A 1 56 ? 3.989 -16.367 75.573 1.00 23.13 ? 56 GLY A C 1 ATOM 397 O O . GLY A 1 56 ? 2.981 -16.916 75.131 1.00 21.87 ? 56 GLY A O 1 ATOM 398 N N . ASN A 1 57 ? 4.073 -15.064 75.807 1.00 22.98 ? 57 ASN A N 1 ATOM 399 C CA . ASN A 1 57 ? 2.976 -14.140 75.540 1.00 23.16 ? 57 ASN A CA 1 ATOM 400 C C . ASN A 1 57 ? 3.070 -13.456 74.172 1.00 22.62 ? 57 ASN A C 1 ATOM 401 O O . ASN A 1 57 ? 4.158 -13.257 73.606 1.00 22.26 ? 57 ASN A O 1 ATOM 402 C CB . ASN A 1 57 ? 2.821 -13.084 76.660 1.00 23.21 ? 57 ASN A CB 1 ATOM 403 C CG . ASN A 1 57 ? 2.648 -13.700 78.049 1.00 22.39 ? 57 ASN A CG 1 ATOM 404 O OD1 . ASN A 1 57 ? 2.204 -14.823 78.192 1.00 24.47 ? 57 ASN A OD1 1 ATOM 405 N ND2 . ASN A 1 57 ? 3.021 -12.951 79.073 1.00 24.02 ? 57 ASN A ND2 1 ATOM 406 N N . LEU A 1 58 ? 1.899 -13.134 73.637 1.00 21.39 ? 58 LEU A N 1 ATOM 407 C CA . LEU A 1 58 ? 1.768 -12.204 72.533 1.00 21.09 ? 58 LEU A CA 1 ATOM 408 C C . LEU A 1 58 ? 2.176 -10.834 73.024 1.00 20.45 ? 58 LEU A C 1 ATOM 409 O O . LEU A 1 58 ? 1.967 -10.489 74.183 1.00 20.66 ? 58 LEU A O 1 ATOM 410 C CB . LEU A 1 58 ? 0.314 -12.179 71.988 1.00 21.20 ? 58 LEU A CB 1 ATOM 411 C CG . LEU A 1 58 ? -0.072 -13.134 70.860 1.00 21.09 ? 58 LEU A CG 1 ATOM 412 C CD1 . LEU A 1 58 ? 0.462 -14.516 71.123 1.00 22.16 ? 58 LEU A CD1 1 ATOM 413 C CD2 . LEU A 1 58 ? -1.589 -13.200 70.686 1.00 21.12 ? 58 LEU A CD2 1 ATOM 414 N N . VAL A 1 59 ? 2.766 -10.054 72.136 1.00 20.57 ? 59 VAL A N 1 ATOM 415 C CA . VAL A 1 59 ? 3.270 -8.739 72.468 1.00 20.45 ? 59 VAL A CA 1 ATOM 416 C C . VAL A 1 59 ? 2.495 -7.730 71.633 1.00 20.62 ? 59 VAL A C 1 ATOM 417 O O . VAL A 1 59 ? 2.524 -7.809 70.431 1.00 19.94 ? 59 VAL A O 1 ATOM 418 C CB . VAL A 1 59 ? 4.790 -8.624 72.107 1.00 20.82 ? 59 VAL A CB 1 ATOM 419 C CG1 . VAL A 1 59 ? 5.306 -7.228 72.389 1.00 21.11 ? 59 VAL A CG1 1 ATOM 420 C CG2 . VAL A 1 59 ? 5.612 -9.671 72.872 1.00 20.49 ? 59 VAL A CG2 1 ATOM 421 N N . ASN A 1 60 ? 1.822 -6.774 72.274 1.00 20.95 ? 60 ASN A N 1 ATOM 422 C CA . ASN A 1 60 ? 1.249 -5.647 71.559 1.00 20.87 ? 60 ASN A CA 1 ATOM 423 C C . ASN A 1 60 ? 2.279 -4.754 70.894 1.00 21.43 ? 60 ASN A C 1 ATOM 424 O O . ASN A 1 60 ? 3.292 -4.403 71.503 1.00 20.99 ? 60 ASN A O 1 ATOM 425 C CB . ASN A 1 60 ? 0.413 -4.802 72.505 1.00 20.88 ? 60 ASN A CB 1 ATOM 426 C CG . ASN A 1 60 ? -0.853 -5.496 72.918 1.00 21.71 ? 60 ASN A CG 1 ATOM 427 O OD1 . ASN A 1 60 ? -1.860 -5.443 72.211 1.00 23.94 ? 60 ASN A OD1 1 ATOM 428 N ND2 . ASN A 1 60 ? -0.821 -6.145 74.073 1.00 20.05 ? 60 ASN A ND2 1 ATOM 429 N N . THR A 1 61 ? 1.991 -4.361 69.650 1.00 21.50 ? 61 THR A N 1 ATOM 430 C CA . THR A 1 61 ? 2.802 -3.413 68.907 1.00 22.32 ? 61 THR A CA 1 ATOM 431 C C . THR A 1 61 ? 1.870 -2.245 68.553 1.00 23.00 ? 61 THR A C 1 ATOM 432 O O . THR A 1 61 ? 0.669 -2.327 68.818 1.00 22.56 ? 61 THR A O 1 ATOM 433 C CB . THR A 1 61 ? 3.313 -4.046 67.606 1.00 22.51 ? 61 THR A CB 1 ATOM 434 O OG1 . THR A 1 61 ? 2.180 -4.502 66.837 1.00 22.78 ? 61 THR A OG1 1 ATOM 435 C CG2 . THR A 1 61 ? 4.275 -5.226 67.894 1.00 20.16 ? 61 THR A CG2 1 ATOM 436 N N . ASN A 1 62 ? 2.407 -1.176 67.956 1.00 23.46 ? 62 ASN A N 1 ATOM 437 C CA . ASN A 1 62 ? 1.560 -0.055 67.454 1.00 24.33 ? 62 ASN A CA 1 ATOM 438 C C . ASN A 1 62 ? 0.536 -0.506 66.406 1.00 23.23 ? 62 ASN A C 1 ATOM 439 O O . ASN A 1 62 ? -0.620 -0.035 66.401 1.00 23.58 ? 62 ASN A O 1 ATOM 440 C CB . ASN A 1 62 ? 2.424 1.091 66.899 1.00 24.94 ? 62 ASN A CB 1 ATOM 441 C CG . ASN A 1 62 ? 3.238 1.825 68.000 1.00 28.66 ? 62 ASN A CG 1 ATOM 442 O OD1 . ASN A 1 62 ? 4.363 2.293 67.760 1.00 32.21 ? 62 ASN A OD1 1 ATOM 443 N ND2 . ASN A 1 62 ? 2.667 1.929 69.190 1.00 30.06 ? 62 ASN A ND2 1 ATOM 444 N N . ALA A 1 63 ? 0.960 -1.451 65.561 1.00 21.94 ? 63 ALA A N 1 ATOM 445 C CA . ALA A 1 63 ? 0.178 -1.973 64.444 1.00 21.38 ? 63 ALA A CA 1 ATOM 446 C C . ALA A 1 63 ? -0.820 -3.089 64.791 1.00 20.71 ? 63 ALA A C 1 ATOM 447 O O . ALA A 1 63 ? -1.829 -3.265 64.090 1.00 20.74 ? 63 ALA A O 1 ATOM 448 C CB . ALA A 1 63 ? 1.127 -2.454 63.342 1.00 21.49 ? 63 ALA A CB 1 ATOM 449 N N . GLY A 1 64 ? -0.512 -3.848 65.842 1.00 19.58 ? 64 GLY A N 1 ATOM 450 C CA . GLY A 1 64 ? -1.231 -5.041 66.226 1.00 18.83 ? 64 GLY A CA 1 ATOM 451 C C . GLY A 1 64 ? -0.493 -5.807 67.311 1.00 18.81 ? 64 GLY A C 1 ATOM 452 O O . GLY A 1 64 ? -0.488 -5.403 68.473 1.00 19.01 ? 64 GLY A O 1 ATOM 453 N N . PHE A 1 65 ? 0.102 -6.936 66.936 1.00 18.61 ? 65 PHE A N 1 ATOM 454 C CA . PHE A 1 65 ? 0.831 -7.791 67.857 1.00 18.66 ? 65 PHE A CA 1 ATOM 455 C C . PHE A 1 65 ? 1.780 -8.742 67.113 1.00 18.75 ? 65 PHE A C 1 ATOM 456 O O . PHE A 1 65 ? 1.644 -8.953 65.914 1.00 18.07 ? 65 PHE A O 1 ATOM 457 C CB . PHE A 1 65 ? -0.122 -8.620 68.722 1.00 18.78 ? 65 PHE A CB 1 ATOM 458 C CG . PHE A 1 65 ? -0.952 -9.617 67.935 1.00 20.40 ? 65 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 65 ? -0.472 -10.905 67.691 1.00 18.95 ? 65 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 65 ? -2.212 -9.259 67.448 1.00 21.33 ? 65 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 65 ? -1.234 -11.824 66.982 1.00 19.18 ? 65 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 65 ? -2.992 -10.165 66.756 1.00 20.96 ? 65 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 65 ? -2.496 -11.449 66.505 1.00 20.04 ? 65 PHE A CZ 1 ATOM 464 N N . THR A 1 66 ? 2.733 -9.292 67.861 1.00 18.57 ? 66 THR A N 1 ATOM 465 C CA . THR A 1 66 ? 3.625 -10.350 67.392 1.00 20.10 ? 66 THR A CA 1 ATOM 466 C C . THR A 1 66 ? 3.522 -11.541 68.350 1.00 20.33 ? 66 THR A C 1 ATOM 467 O O . THR A 1 66 ? 3.134 -11.387 69.516 1.00 21.25 ? 66 THR A O 1 ATOM 468 C CB . THR A 1 66 ? 5.128 -9.857 67.331 1.00 20.31 ? 66 THR A CB 1 ATOM 469 O OG1 . THR A 1 66 ? 5.525 -9.371 68.612 1.00 20.97 ? 66 THR A OG1 1 ATOM 470 C CG2 . THR A 1 66 ? 5.287 -8.720 66.343 1.00 19.93 ? 66 THR A CG2 1 ATOM 471 N N . ALA A 1 67 ? 3.859 -12.732 67.860 1.00 20.12 ? 67 ALA A N 1 ATOM 472 C CA . ALA A 1 67 ? 3.880 -13.931 68.673 1.00 20.36 ? 67 ALA A CA 1 ATOM 473 C C . ALA A 1 67 ? 5.048 -14.776 68.228 1.00 21.08 ? 67 ALA A C 1 ATOM 474 O O . ALA A 1 67 ? 5.349 -14.844 67.048 1.00 20.24 ? 67 ALA A O 1 ATOM 475 C CB . ALA A 1 67 ? 2.608 -14.723 68.478 1.00 19.32 ? 67 ALA A CB 1 ATOM 476 N N . ARG A 1 68 ? 5.673 -15.456 69.174 1.00 22.65 ? 68 ARG A N 1 ATOM 477 C CA . ARG A 1 68 ? 6.718 -16.412 68.824 1.00 24.01 ? 68 ARG A CA 1 ATOM 478 C C . ARG A 1 68 ? 6.100 -17.782 68.750 1.00 23.83 ? 68 ARG A C 1 ATOM 479 O O . ARG A 1 68 ? 5.416 -18.210 69.695 1.00 23.51 ? 68 ARG A O 1 ATOM 480 C CB . ARG A 1 68 ? 7.853 -16.363 69.835 1.00 24.59 ? 68 ARG A CB 1 ATOM 481 C CG . ARG A 1 68 ? 8.563 -15.024 69.836 1.00 28.16 ? 68 ARG A CG 1 ATOM 482 C CD . ARG A 1 68 ? 9.249 -14.721 71.192 1.00 34.92 ? 68 ARG A CD 1 ATOM 483 N NE . ARG A 1 68 ? 10.410 -13.833 71.036 1.00 41.79 ? 68 ARG A NE 1 ATOM 484 C CZ . ARG A 1 68 ? 11.000 -13.148 72.022 1.00 44.02 ? 68 ARG A CZ 1 ATOM 485 N NH1 . ARG A 1 68 ? 10.544 -13.217 73.272 1.00 44.40 ? 68 ARG A NH1 1 ATOM 486 N NH2 . ARG A 1 68 ? 12.048 -12.375 71.748 1.00 44.07 ? 68 ARG A NH2 1 ATOM 487 N N . LEU A 1 69 ? 6.298 -18.443 67.607 1.00 23.48 ? 69 LEU A N 1 ATOM 488 C CA . LEU A 1 69 ? 5.861 -19.814 67.429 1.00 24.88 ? 69 LEU A CA 1 ATOM 489 C C . LEU A 1 69 ? 7.073 -20.751 67.431 1.00 26.42 ? 69 LEU A C 1 ATOM 490 O O . LEU A 1 69 ? 8.099 -20.455 66.821 1.00 25.71 ? 69 LEU A O 1 ATOM 491 C CB . LEU A 1 69 ? 5.041 -19.986 66.146 1.00 24.57 ? 69 LEU A CB 1 ATOM 492 C CG . LEU A 1 69 ? 4.019 -18.921 65.737 1.00 24.51 ? 69 LEU A CG 1 ATOM 493 C CD1 . LEU A 1 69 ? 3.072 -19.493 64.675 1.00 24.25 ? 69 LEU A CD1 1 ATOM 494 C CD2 . LEU A 1 69 ? 3.261 -18.430 66.949 1.00 23.83 ? 69 LEU A CD2 1 ATOM 495 N N . LYS A 1 70 ? 6.950 -21.857 68.152 1.00 28.35 ? 70 LYS A N 1 ATOM 496 C CA . LYS A 1 70 ? 8.020 -22.820 68.259 1.00 31.68 ? 70 LYS A CA 1 ATOM 497 C C . LYS A 1 70 ? 7.521 -24.112 67.627 1.00 32.95 ? 70 LYS A C 1 ATOM 498 O O . LYS A 1 70 ? 6.400 -24.541 67.893 1.00 32.08 ? 70 LYS A O 1 ATOM 499 C CB . LYS A 1 70 ? 8.394 -23.023 69.740 1.00 31.67 ? 70 LYS A CB 1 ATOM 500 C CG . LYS A 1 70 ? 9.848 -23.509 70.043 1.00 33.63 ? 70 LYS A CG 1 ATOM 501 C CD . LYS A 1 70 ? 10.213 -23.176 71.510 1.00 33.18 ? 70 LYS A CD 1 ATOM 502 C CE . LYS A 1 70 ? 11.254 -24.146 72.122 1.00 38.82 ? 70 LYS A CE 1 ATOM 503 N NZ . LYS A 1 70 ? 11.231 -24.149 73.628 1.00 37.96 ? 70 LYS A NZ 1 ATOM 504 N N . ASN A 1 71 ? 8.349 -24.708 66.768 1.00 35.37 ? 71 ASN A N 1 ATOM 505 C CA . ASN A 1 71 ? 8.047 -25.999 66.153 1.00 38.32 ? 71 ASN A CA 1 ATOM 506 C C . ASN A 1 71 ? 7.965 -27.122 67.201 1.00 40.26 ? 71 ASN A C 1 ATOM 507 O O . ASN A 1 71 ? 8.904 -27.323 67.982 1.00 40.40 ? 71 ASN A O 1 ATOM 508 C CB . ASN A 1 71 ? 9.114 -26.323 65.086 1.00 38.35 ? 71 ASN A CB 1 ATOM 509 C CG . ASN A 1 71 ? 8.726 -27.478 64.173 1.00 39.77 ? 71 ASN A CG 1 ATOM 510 O OD1 . ASN A 1 71 ? 7.598 -27.558 63.675 1.00 40.10 ? 71 ASN A OD1 1 ATOM 511 N ND2 . ASN A 1 71 ? 9.686 -28.379 63.927 1.00 41.72 ? 71 ASN A ND2 1 ATOM 512 N N . LEU A 1 72 ? 6.838 -27.835 67.220 1.00 42.54 ? 72 LEU A N 1 ATOM 513 C CA . LEU A 1 72 ? 6.731 -29.099 67.938 1.00 44.92 ? 72 LEU A CA 1 ATOM 514 C C . LEU A 1 72 ? 7.442 -30.136 67.077 1.00 46.59 ? 72 LEU A C 1 ATOM 515 O O . LEU A 1 72 ? 6.948 -30.472 65.999 1.00 46.81 ? 72 LEU A O 1 ATOM 516 C CB . LEU A 1 72 ? 5.270 -29.540 68.097 1.00 45.23 ? 72 LEU A CB 1 ATOM 517 C CG . LEU A 1 72 ? 4.263 -29.083 69.162 1.00 45.81 ? 72 LEU A CG 1 ATOM 518 C CD1 . LEU A 1 72 ? 4.900 -28.851 70.542 1.00 46.52 ? 72 LEU A CD1 1 ATOM 519 C CD2 . LEU A 1 72 ? 3.487 -27.883 68.685 1.00 45.20 ? 72 LEU A CD2 1 ATOM 520 N N . PRO A 1 73 ? 8.604 -30.644 67.529 1.00 48.29 ? 73 PRO A N 1 ATOM 521 C CA . PRO A 1 73 ? 9.370 -31.540 66.652 1.00 49.31 ? 73 PRO A CA 1 ATOM 522 C C . PRO A 1 73 ? 8.495 -32.586 65.957 1.00 49.92 ? 73 PRO A C 1 ATOM 523 O O . PRO A 1 73 ? 7.608 -33.181 66.588 1.00 50.08 ? 73 PRO A O 1 ATOM 524 C CB . PRO A 1 73 ? 10.355 -32.203 67.615 1.00 49.42 ? 73 PRO A CB 1 ATOM 525 C CG . PRO A 1 73 ? 10.626 -31.137 68.618 1.00 49.60 ? 73 PRO A CG 1 ATOM 526 C CD . PRO A 1 73 ? 9.279 -30.451 68.828 1.00 48.72 ? 73 PRO A CD 1 ATOM 527 N N . SER A 1 74 ? 8.720 -32.751 64.657 1.00 50.18 ? 74 SER A N 1 ATOM 528 C CA . SER A 1 74 ? 8.089 -33.808 63.875 1.00 50.79 ? 74 SER A CA 1 ATOM 529 C C . SER A 1 74 ? 9.002 -34.194 62.720 1.00 50.97 ? 74 SER A C 1 ATOM 530 O O . SER A 1 74 ? 10.119 -33.685 62.621 1.00 50.81 ? 74 SER A O 1 ATOM 531 C CB . SER A 1 74 ? 6.713 -33.386 63.349 1.00 50.96 ? 74 SER A CB 1 ATOM 532 O OG . SER A 1 74 ? 5.995 -34.529 62.902 1.00 51.20 ? 74 SER A OG 1 ATOM 533 N N . SER A 1 75 ? 8.511 -35.083 61.853 1.00 51.22 ? 75 SER A N 1 ATOM 534 C CA . SER A 1 75 ? 9.278 -35.599 60.719 1.00 51.24 ? 75 SER A CA 1 ATOM 535 C C . SER A 1 75 ? 9.674 -34.520 59.720 1.00 51.08 ? 75 SER A C 1 ATOM 536 O O . SER A 1 75 ? 8.860 -33.658 59.386 1.00 51.53 ? 75 SER A O 1 ATOM 537 C CB . SER A 1 75 ? 8.511 -36.719 60.012 1.00 51.17 ? 75 SER A CB 1 ATOM 538 O OG . SER A 1 75 ? 8.707 -37.946 60.691 1.00 51.28 ? 75 SER A OG 1 ATOM 539 N N . PRO A 1 76 ? 10.943 -34.554 59.263 1.00 50.84 ? 76 PRO A N 1 ATOM 540 C CA . PRO A 1 76 ? 11.424 -33.674 58.206 1.00 50.26 ? 76 PRO A CA 1 ATOM 541 C C . PRO A 1 76 ? 11.155 -34.279 56.820 1.00 49.61 ? 76 PRO A C 1 ATOM 542 O O . PRO A 1 76 ? 12.020 -34.967 56.248 1.00 50.02 ? 76 PRO A O 1 ATOM 543 C CB . PRO A 1 76 ? 12.932 -33.569 58.492 1.00 50.32 ? 76 PRO A CB 1 ATOM 544 C CG . PRO A 1 76 ? 13.236 -34.607 59.537 1.00 50.56 ? 76 PRO A CG 1 ATOM 545 C CD . PRO A 1 76 ? 12.015 -35.438 59.743 1.00 50.90 ? 76 PRO A CD 1 ATOM 546 N N . VAL A 1 77 ? 9.958 -34.017 56.293 1.00 48.49 ? 77 VAL A N 1 ATOM 547 C CA . VAL A 1 77 ? 9.500 -34.606 55.032 1.00 47.29 ? 77 VAL A CA 1 ATOM 548 C C . VAL A 1 77 ? 10.058 -33.894 53.799 1.00 46.41 ? 77 VAL A C 1 ATOM 549 O O . VAL A 1 77 ? 10.663 -34.523 52.915 1.00 46.58 ? 77 VAL A O 1 ATOM 550 C CB . VAL A 1 77 ? 7.961 -34.614 54.955 1.00 47.53 ? 77 VAL A CB 1 ATOM 551 C CG1 . VAL A 1 77 ? 7.493 -35.216 53.641 1.00 47.56 ? 77 VAL A CG1 1 ATOM 552 C CG2 . VAL A 1 77 ? 7.381 -35.374 56.132 1.00 47.92 ? 77 VAL A CG2 1 ATOM 553 N N . PHE A 1 78 ? 9.840 -32.586 53.725 1.00 44.58 ? 78 PHE A N 1 ATOM 554 C CA . PHE A 1 78 ? 10.283 -31.827 52.567 1.00 42.87 ? 78 PHE A CA 1 ATOM 555 C C . PHE A 1 78 ? 11.421 -30.896 52.947 1.00 42.59 ? 78 PHE A C 1 ATOM 556 O O . PHE A 1 78 ? 11.481 -29.738 52.531 1.00 42.24 ? 78 PHE A O 1 ATOM 557 C CB . PHE A 1 78 ? 9.117 -31.091 51.920 1.00 41.56 ? 78 PHE A CB 1 ATOM 558 C CG . PHE A 1 78 ? 7.967 -31.982 51.569 1.00 39.67 ? 78 PHE A CG 1 ATOM 559 C CD1 . PHE A 1 78 ? 6.731 -31.802 52.169 1.00 36.68 ? 78 PHE A CD1 1 ATOM 560 C CD2 . PHE A 1 78 ? 8.120 -33.010 50.647 1.00 36.94 ? 78 PHE A CD2 1 ATOM 561 C CE1 . PHE A 1 78 ? 5.646 -32.624 51.840 1.00 38.75 ? 78 PHE A CE1 1 ATOM 562 C CE2 . PHE A 1 78 ? 7.051 -33.829 50.316 1.00 37.35 ? 78 PHE A CE2 1 ATOM 563 C CZ . PHE A 1 78 ? 5.809 -33.634 50.919 1.00 38.00 ? 78 PHE A CZ 1 ATOM 564 N N . GLY A 1 79 ? 12.317 -31.429 53.766 1.00 42.80 ? 79 GLY A N 1 ATOM 565 C CA . GLY A 1 79 ? 13.567 -30.762 54.090 1.00 42.56 ? 79 GLY A CA 1 ATOM 566 C C . GLY A 1 79 ? 13.583 -29.877 55.318 1.00 42.31 ? 79 GLY A C 1 ATOM 567 O O . GLY A 1 79 ? 12.762 -30.026 56.235 1.00 42.81 ? 79 GLY A O 1 ATOM 568 N N . SER A 1 80 ? 14.541 -28.952 55.290 1.00 42.13 ? 80 SER A N 1 ATOM 569 C CA . SER A 1 80 ? 14.939 -28.071 56.385 1.00 41.18 ? 80 SER A CA 1 ATOM 570 C C . SER A 1 80 ? 13.800 -27.207 56.967 1.00 40.22 ? 80 SER A C 1 ATOM 571 O O . SER A 1 80 ? 13.453 -26.155 56.426 1.00 39.54 ? 80 SER A O 1 ATOM 572 C CB . SER A 1 80 ? 16.109 -27.195 55.908 1.00 41.66 ? 80 SER A CB 1 ATOM 573 O OG . SER A 1 80 ? 16.982 -26.875 56.977 1.00 43.09 ? 80 SER A OG 1 ATOM 574 N N . ASN A 1 81 ? 13.271 -27.678 58.096 1.00 38.76 ? 81 ASN A N 1 ATOM 575 C CA . ASN A 1 81 ? 12.171 -27.078 58.829 1.00 37.87 ? 81 ASN A CA 1 ATOM 576 C C . ASN A 1 81 ? 12.579 -25.808 59.611 1.00 37.24 ? 81 ASN A C 1 ATOM 577 O O . ASN A 1 81 ? 13.762 -25.604 59.932 1.00 36.63 ? 81 ASN A O 1 ATOM 578 C CB . ASN A 1 81 ? 11.603 -28.145 59.759 1.00 37.94 ? 81 ASN A CB 1 ATOM 579 C CG . ASN A 1 81 ? 10.246 -27.796 60.302 1.00 39.06 ? 81 ASN A CG 1 ATOM 580 O OD1 . ASN A 1 81 ? 10.132 -27.017 61.242 1.00 40.32 ? 81 ASN A OD1 1 ATOM 581 N ND2 . ASN A 1 81 ? 9.197 -28.415 59.745 1.00 41.34 ? 81 ASN A ND2 1 ATOM 582 N N . VAL A 1 82 ? 11.593 -24.953 59.892 1.00 35.83 ? 82 VAL A N 1 ATOM 583 C CA . VAL A 1 82 ? 11.829 -23.670 60.560 1.00 34.43 ? 82 VAL A CA 1 ATOM 584 C C . VAL A 1 82 ? 11.350 -23.748 62.008 1.00 34.12 ? 82 VAL A C 1 ATOM 585 O O . VAL A 1 82 ? 10.133 -23.810 62.279 1.00 34.02 ? 82 VAL A O 1 ATOM 586 C CB . VAL A 1 82 ? 11.231 -22.478 59.749 1.00 34.47 ? 82 VAL A CB 1 ATOM 587 C CG1 . VAL A 1 82 ? 11.225 -21.193 60.547 1.00 33.27 ? 82 VAL A CG1 1 ATOM 588 C CG2 . VAL A 1 82 ? 12.005 -22.285 58.440 1.00 32.89 ? 82 VAL A CG2 1 ATOM 589 N N . ASP A 1 83 ? 12.326 -23.789 62.922 1.00 32.84 ? 83 ASP A N 1 ATOM 590 C CA . ASP A 1 83 ? 12.084 -24.059 64.352 1.00 33.11 ? 83 ASP A CA 1 ATOM 591 C C . ASP A 1 83 ? 11.438 -22.905 65.105 1.00 31.52 ? 83 ASP A C 1 ATOM 592 O O . ASP A 1 83 ? 10.615 -23.130 65.981 1.00 32.12 ? 83 ASP A O 1 ATOM 593 C CB . ASP A 1 83 ? 13.375 -24.435 65.094 1.00 33.26 ? 83 ASP A CB 1 ATOM 594 C CG . ASP A 1 83 ? 13.892 -25.821 64.730 1.00 36.93 ? 83 ASP A CG 1 ATOM 595 O OD1 . ASP A 1 83 ? 13.101 -26.680 64.254 1.00 37.41 ? 83 ASP A OD1 1 ATOM 596 O OD2 . ASP A 1 83 ? 15.117 -26.043 64.934 1.00 40.08 ? 83 ASP A OD2 1 ATOM 597 N N . ASN A 1 84 ? 11.848 -21.682 64.801 1.00 29.84 ? 84 ASN A N 1 ATOM 598 C CA . ASN A 1 84 ? 11.257 -20.505 65.444 1.00 28.81 ? 84 ASN A CA 1 ATOM 599 C C . ASN A 1 84 ? 10.654 -19.554 64.439 1.00 26.79 ? 84 ASN A C 1 ATOM 600 O O . ASN A 1 84 ? 11.374 -18.901 63.680 1.00 26.10 ? 84 ASN A O 1 ATOM 601 C CB . ASN A 1 84 ? 12.277 -19.786 66.322 1.00 29.18 ? 84 ASN A CB 1 ATOM 602 C CG . ASN A 1 84 ? 12.701 -20.622 67.505 1.00 31.23 ? 84 ASN A CG 1 ATOM 603 O OD1 . ASN A 1 84 ? 13.780 -21.210 67.499 1.00 36.61 ? 84 ASN A OD1 1 ATOM 604 N ND2 . ASN A 1 84 ? 11.849 -20.703 68.514 1.00 33.66 ? 84 ASN A ND2 1 ATOM 605 N N . VAL A 1 85 ? 9.324 -19.501 64.447 1.00 24.84 ? 85 VAL A N 1 ATOM 606 C CA . VAL A 1 85 ? 8.535 -18.687 63.509 1.00 23.27 ? 85 VAL A CA 1 ATOM 607 C C . VAL A 1 85 ? 7.991 -17.438 64.230 1.00 22.55 ? 85 VAL A C 1 ATOM 608 O O . VAL A 1 85 ? 7.660 -17.508 65.405 1.00 22.19 ? 85 VAL A O 1 ATOM 609 C CB . VAL A 1 85 ? 7.358 -19.533 62.881 1.00 23.44 ? 85 VAL A CB 1 ATOM 610 C CG1 . VAL A 1 85 ? 6.359 -18.652 62.141 1.00 21.35 ? 85 VAL A CG1 1 ATOM 611 C CG2 . VAL A 1 85 ? 7.915 -20.552 61.908 1.00 22.31 ? 85 VAL A CG2 1 ATOM 612 N N . LEU A 1 86 ? 7.957 -16.300 63.533 1.00 21.05 ? 86 LEU A N 1 ATOM 613 C CA . LEU A 1 86 ? 7.426 -15.086 64.081 1.00 20.22 ? 86 LEU A CA 1 ATOM 614 C C . LEU A 1 86 ? 6.096 -14.802 63.398 1.00 19.96 ? 86 LEU A C 1 ATOM 615 O O . LEU A 1 86 ? 5.995 -14.767 62.180 1.00 20.21 ? 86 LEU A O 1 ATOM 616 C CB . LEU A 1 86 ? 8.392 -13.900 63.901 1.00 20.12 ? 86 LEU A CB 1 ATOM 617 C CG . LEU A 1 86 ? 7.977 -12.559 64.512 1.00 19.84 ? 86 LEU A CG 1 ATOM 618 C CD1 . LEU A 1 86 ? 8.112 -12.526 66.031 1.00 21.08 ? 86 LEU A CD1 1 ATOM 619 C CD2 . LEU A 1 86 ? 8.737 -11.395 63.885 1.00 20.20 ? 86 LEU A CD2 1 ATOM 620 N N . LEU A 1 87 ? 5.069 -14.627 64.197 1.00 18.70 ? 87 LEU A N 1 ATOM 621 C CA . LEU A 1 87 ? 3.831 -14.110 63.673 1.00 17.85 ? 87 LEU A CA 1 ATOM 622 C C . LEU A 1 87 ? 3.801 -12.608 63.938 1.00 17.31 ? 87 LEU A C 1 ATOM 623 O O . LEU A 1 87 ? 3.986 -12.177 65.061 1.00 16.59 ? 87 LEU A O 1 ATOM 624 C CB . LEU A 1 87 ? 2.659 -14.836 64.346 1.00 17.40 ? 87 LEU A CB 1 ATOM 625 C CG . LEU A 1 87 ? 1.286 -14.183 64.138 1.00 17.32 ? 87 LEU A CG 1 ATOM 626 C CD1 . LEU A 1 87 ? 0.859 -14.268 62.672 1.00 14.83 ? 87 LEU A CD1 1 ATOM 627 C CD2 . LEU A 1 87 ? 0.312 -14.898 65.042 1.00 15.34 ? 87 LEU A CD2 1 ATOM 628 N N . THR A 1 88 ? 3.598 -11.823 62.886 1.00 18.09 ? 88 THR A N 1 ATOM 629 C CA . THR A 1 88 ? 3.433 -10.392 62.973 1.00 18.90 ? 88 THR A CA 1 ATOM 630 C C . THR A 1 88 ? 2.045 -10.102 62.397 1.00 19.58 ? 88 THR A C 1 ATOM 631 O O . THR A 1 88 ? 1.772 -10.444 61.241 1.00 19.68 ? 88 THR A O 1 ATOM 632 C CB . THR A 1 88 ? 4.532 -9.697 62.156 1.00 19.05 ? 88 THR A CB 1 ATOM 633 O OG1 . THR A 1 88 ? 5.810 -10.120 62.655 1.00 21.87 ? 88 THR A OG1 1 ATOM 634 C CG2 . THR A 1 88 ? 4.453 -8.171 62.245 1.00 20.75 ? 88 THR A CG2 1 ATOM 635 N N . ALA A 1 89 ? 1.165 -9.534 63.220 1.00 19.73 ? 89 ALA A N 1 ATOM 636 C CA . ALA A 1 89 ? -0.200 -9.192 62.814 1.00 19.06 ? 89 ALA A CA 1 ATOM 637 C C . ALA A 1 89 ? -0.420 -7.697 62.845 1.00 19.45 ? 89 ALA A C 1 ATOM 638 O O . ALA A 1 89 ? -0.049 -7.022 63.824 1.00 19.29 ? 89 ALA A O 1 ATOM 639 C CB . ALA A 1 89 ? -1.217 -9.911 63.707 1.00 19.68 ? 89 ALA A CB 1 ATOM 640 N N . GLU A 1 90 ? -1.010 -7.163 61.766 1.00 18.84 ? 90 GLU A N 1 ATOM 641 C CA . GLU A 1 90 ? -1.209 -5.730 61.625 1.00 18.51 ? 90 GLU A CA 1 ATOM 642 C C . GLU A 1 90 ? -2.684 -5.427 61.303 1.00 18.39 ? 90 GLU A C 1 ATOM 643 O O . GLU A 1 90 ? -3.222 -5.892 60.313 1.00 16.97 ? 90 GLU A O 1 ATOM 644 C CB . GLU A 1 90 ? -0.276 -5.140 60.564 1.00 17.78 ? 90 GLU A CB 1 ATOM 645 C CG . GLU A 1 90 ? 1.219 -5.212 60.960 1.00 19.69 ? 90 GLU A CG 1 ATOM 646 C CD . GLU A 1 90 ? 2.173 -4.837 59.841 1.00 21.63 ? 90 GLU A CD 1 ATOM 647 O OE1 . GLU A 1 90 ? 1.768 -4.939 58.663 1.00 25.40 ? 90 GLU A OE1 1 ATOM 648 O OE2 . GLU A 1 90 ? 3.340 -4.433 60.140 1.00 27.12 ? 90 GLU A OE2 1 ATOM 649 N N . TYR A 1 91 ? -3.303 -4.653 62.176 1.00 17.64 ? 91 TYR A N 1 ATOM 650 C CA . TYR A 1 91 ? -4.683 -4.179 62.031 1.00 18.08 ? 91 TYR A CA 1 ATOM 651 C C . TYR A 1 91 ? -4.674 -2.964 61.109 1.00 16.21 ? 91 TYR A C 1 ATOM 652 O O . TYR A 1 91 ? -4.713 -1.824 61.554 1.00 17.22 ? 91 TYR A O 1 ATOM 653 C CB . TYR A 1 91 ? -5.195 -3.809 63.420 1.00 18.68 ? 91 TYR A CB 1 ATOM 654 C CG . TYR A 1 91 ? -5.352 -4.989 64.376 1.00 20.59 ? 91 TYR A CG 1 ATOM 655 C CD1 . TYR A 1 91 ? -6.295 -5.976 64.142 1.00 22.03 ? 91 TYR A CD1 1 ATOM 656 C CD2 . TYR A 1 91 ? -4.618 -5.065 65.559 1.00 22.92 ? 91 TYR A CD2 1 ATOM 657 C CE1 . TYR A 1 91 ? -6.459 -7.055 65.024 1.00 21.94 ? 91 TYR A CE1 1 ATOM 658 C CE2 . TYR A 1 91 ? -4.794 -6.144 66.465 1.00 22.54 ? 91 TYR A CE2 1 ATOM 659 C CZ . TYR A 1 91 ? -5.709 -7.129 66.174 1.00 20.98 ? 91 TYR A CZ 1 ATOM 660 O OH . TYR A 1 91 ? -5.918 -8.182 67.036 1.00 21.79 ? 91 TYR A OH 1 ATOM 661 N N . GLN A 1 92 ? -4.573 -3.191 59.811 1.00 16.09 ? 92 GLN A N 1 ATOM 662 C CA . GLN A 1 92 ? -4.129 -2.127 58.912 1.00 15.75 ? 92 GLN A CA 1 ATOM 663 C C . GLN A 1 92 ? -5.222 -1.086 58.646 1.00 15.84 ? 92 GLN A C 1 ATOM 664 O O . GLN A 1 92 ? -4.952 0.089 58.606 1.00 15.42 ? 92 GLN A O 1 ATOM 665 C CB . GLN A 1 92 ? -3.614 -2.710 57.600 1.00 15.74 ? 92 GLN A CB 1 ATOM 666 C CG . GLN A 1 92 ? -2.231 -3.377 57.737 1.00 15.51 ? 92 GLN A CG 1 ATOM 667 C CD . GLN A 1 92 ? -1.571 -3.692 56.392 1.00 16.13 ? 92 GLN A CD 1 ATOM 668 O OE1 . GLN A 1 92 ? -2.211 -3.665 55.337 1.00 13.01 ? 92 GLN A OE1 1 ATOM 669 N NE2 . GLN A 1 92 ? -0.265 -3.999 56.436 1.00 15.85 ? 92 GLN A NE2 1 ATOM 670 N N . THR A 1 93 ? -6.454 -1.545 58.471 1.00 16.12 ? 93 THR A N 1 ATOM 671 C CA . THR A 1 93 ? -7.599 -0.650 58.271 1.00 16.18 ? 93 THR A CA 1 ATOM 672 C C . THR A 1 93 ? -8.774 -1.325 58.924 1.00 16.47 ? 93 THR A C 1 ATOM 673 O O . THR A 1 93 ? -8.671 -2.460 59.340 1.00 17.05 ? 93 THR A O 1 ATOM 674 C CB . THR A 1 93 ? -7.865 -0.354 56.764 1.00 16.78 ? 93 THR A CB 1 ATOM 675 O OG1 . THR A 1 93 ? -8.634 -1.403 56.176 1.00 17.88 ? 93 THR A OG1 1 ATOM 676 C CG2 . THR A 1 93 ? -6.546 -0.198 55.948 1.00 16.65 ? 93 THR A CG2 1 ATOM 677 N N . SER A 1 94 ? -9.918 -0.652 59.011 1.00 16.73 ? 94 SER A N 1 ATOM 678 C CA . SER A 1 94 ? -11.102 -1.286 59.539 1.00 16.73 ? 94 SER A CA 1 ATOM 679 C C . SER A 1 94 ? -11.493 -2.535 58.768 1.00 15.81 ? 94 SER A C 1 ATOM 680 O O . SER A 1 94 ? -12.181 -3.401 59.304 1.00 16.18 ? 94 SER A O 1 ATOM 681 C CB . SER A 1 94 ? -12.248 -0.271 59.522 1.00 17.55 ? 94 SER A CB 1 ATOM 682 O OG . SER A 1 94 ? -11.917 0.758 60.433 1.00 22.36 ? 94 SER A OG 1 ATOM 683 N N . ASN A 1 95 ? -11.060 -2.639 57.510 1.00 14.97 ? 95 ASN A N 1 ATOM 684 C CA . ASN A 1 95 ? -11.494 -3.736 56.663 1.00 15.87 ? 95 ASN A CA 1 ATOM 685 C C . ASN A 1 95 ? -10.409 -4.667 56.135 1.00 16.50 ? 95 ASN A C 1 ATOM 686 O O . ASN A 1 95 ? -10.708 -5.595 55.410 1.00 17.63 ? 95 ASN A O 1 ATOM 687 C CB . ASN A 1 95 ? -12.315 -3.180 55.511 1.00 16.58 ? 95 ASN A CB 1 ATOM 688 C CG . ASN A 1 95 ? -13.577 -2.542 55.990 1.00 18.80 ? 95 ASN A CG 1 ATOM 689 O OD1 . ASN A 1 95 ? -14.551 -3.231 56.271 1.00 26.84 ? 95 ASN A OD1 1 ATOM 690 N ND2 . ASN A 1 95 ? -13.570 -1.240 56.114 1.00 20.13 ? 95 ASN A ND2 1 ATOM 691 N N . ARG A 1 96 ? -9.159 -4.403 56.497 1.00 15.68 ? 96 ARG A N 1 ATOM 692 C CA . ARG A 1 96 ? -8.030 -5.168 55.979 1.00 15.23 ? 96 ARG A CA 1 ATOM 693 C C . ARG A 1 96 ? -7.159 -5.571 57.143 1.00 14.43 ? 96 ARG A C 1 ATOM 694 O O . ARG A 1 96 ? -6.669 -4.715 57.892 1.00 15.20 ? 96 ARG A O 1 ATOM 695 C CB . ARG A 1 96 ? -7.213 -4.369 54.957 1.00 14.58 ? 96 ARG A CB 1 ATOM 696 C CG . ARG A 1 96 ? -5.961 -5.153 54.438 1.00 15.87 ? 96 ARG A CG 1 ATOM 697 C CD . ARG A 1 96 ? -5.227 -4.408 53.345 1.00 13.99 ? 96 ARG A CD 1 ATOM 698 N NE . ARG A 1 96 ? -4.469 -3.267 53.833 1.00 15.67 ? 96 ARG A NE 1 ATOM 699 C CZ . ARG A 1 96 ? -4.621 -2.032 53.391 1.00 19.49 ? 96 ARG A CZ 1 ATOM 700 N NH1 . ARG A 1 96 ? -5.558 -1.757 52.487 1.00 17.99 ? 96 ARG A NH1 1 ATOM 701 N NH2 . ARG A 1 96 ? -3.838 -1.061 53.855 1.00 20.66 ? 96 ARG A NH2 1 ATOM 702 N N . PHE A 1 97 ? -7.031 -6.876 57.321 1.00 14.77 ? 97 PHE A N 1 ATOM 703 C CA . PHE A 1 97 ? -6.149 -7.461 58.306 1.00 15.16 ? 97 PHE A CA 1 ATOM 704 C C . PHE A 1 97 ? -4.949 -8.029 57.549 1.00 15.75 ? 97 PHE A C 1 ATOM 705 O O . PHE A 1 97 ? -5.115 -8.639 56.479 1.00 13.91 ? 97 PHE A O 1 ATOM 706 C CB . PHE A 1 97 ? -6.874 -8.577 59.074 1.00 14.93 ? 97 PHE A CB 1 ATOM 707 C CG . PHE A 1 97 ? -6.009 -9.270 60.094 1.00 17.25 ? 97 PHE A CG 1 ATOM 708 C CD1 . PHE A 1 97 ? -5.380 -8.541 61.114 1.00 18.75 ? 97 PHE A CD1 1 ATOM 709 C CD2 . PHE A 1 97 ? -5.759 -10.633 59.994 1.00 15.79 ? 97 PHE A CD2 1 ATOM 710 C CE1 . PHE A 1 97 ? -4.539 -9.170 62.033 1.00 16.87 ? 97 PHE A CE1 1 ATOM 711 C CE2 . PHE A 1 97 ? -4.958 -11.269 60.911 1.00 16.89 ? 97 PHE A CE2 1 ATOM 712 C CZ . PHE A 1 97 ? -4.343 -10.546 61.933 1.00 16.21 ? 97 PHE A CZ 1 ATOM 713 N N . HIS A 1 98 ? -3.756 -7.829 58.106 1.00 16.61 ? 98 HIS A N 1 ATOM 714 C CA . HIS A 1 98 ? -2.522 -8.340 57.527 1.00 17.17 ? 98 HIS A CA 1 ATOM 715 C C . HIS A 1 98 ? -1.791 -9.219 58.567 1.00 17.75 ? 98 HIS A C 1 ATOM 716 O O . HIS A 1 98 ? -1.591 -8.813 59.711 1.00 17.60 ? 98 HIS A O 1 ATOM 717 C CB . HIS A 1 98 ? -1.651 -7.158 57.062 1.00 17.90 ? 98 HIS A CB 1 ATOM 718 C CG . HIS A 1 98 ? -0.273 -7.536 56.599 1.00 17.92 ? 98 HIS A CG 1 ATOM 719 N ND1 . HIS A 1 98 ? -0.040 -8.547 55.692 1.00 18.90 ? 98 HIS A ND1 1 ATOM 720 C CD2 . HIS A 1 98 ? 0.947 -7.031 56.916 1.00 20.09 ? 98 HIS A CD2 1 ATOM 721 C CE1 . HIS A 1 98 ? 1.263 -8.656 55.476 1.00 19.73 ? 98 HIS A CE1 1 ATOM 722 N NE2 . HIS A 1 98 ? 1.883 -7.738 56.195 1.00 21.12 ? 98 HIS A NE2 1 ATOM 723 N N . PHE A 1 99 ? -1.428 -10.444 58.195 1.00 18.11 ? 99 PHE A N 1 ATOM 724 C CA . PHE A 1 99 ? -0.524 -11.220 59.052 1.00 18.90 ? 99 PHE A CA 1 ATOM 725 C C . PHE A 1 99 ? 0.560 -11.934 58.259 1.00 19.19 ? 99 PHE A C 1 ATOM 726 O O . PHE A 1 99 ? 0.363 -12.327 57.113 1.00 18.59 ? 99 PHE A O 1 ATOM 727 C CB . PHE A 1 99 ? -1.263 -12.164 60.022 1.00 19.12 ? 99 PHE A CB 1 ATOM 728 C CG . PHE A 1 99 ? -1.801 -13.429 59.390 1.00 20.45 ? 99 PHE A CG 1 ATOM 729 C CD1 . PHE A 1 99 ? -1.036 -14.600 59.372 1.00 18.93 ? 99 PHE A CD1 1 ATOM 730 C CD2 . PHE A 1 99 ? -3.092 -13.461 58.880 1.00 20.54 ? 99 PHE A CD2 1 ATOM 731 C CE1 . PHE A 1 99 ? -1.530 -15.757 58.812 1.00 20.91 ? 99 PHE A CE1 1 ATOM 732 C CE2 . PHE A 1 99 ? -3.611 -14.633 58.325 1.00 20.56 ? 99 PHE A CE2 1 ATOM 733 C CZ . PHE A 1 99 ? -2.844 -15.773 58.296 1.00 21.20 ? 99 PHE A CZ 1 ATOM 734 N N . LYS A 1 100 ? 1.730 -12.052 58.863 1.00 20.25 ? 100 LYS A N 1 ATOM 735 C CA . LYS A 1 100 ? 2.826 -12.758 58.218 1.00 20.87 ? 100 LYS A CA 1 ATOM 736 C C . LYS A 1 100 ? 3.555 -13.660 59.200 1.00 20.62 ? 100 LYS A C 1 ATOM 737 O O . LYS A 1 100 ? 3.691 -13.341 60.389 1.00 19.87 ? 100 LYS A O 1 ATOM 738 C CB . LYS A 1 100 ? 3.755 -11.806 57.446 1.00 21.18 ? 100 LYS A CB 1 ATOM 739 C CG . LYS A 1 100 ? 4.689 -10.931 58.224 1.00 23.79 ? 100 LYS A CG 1 ATOM 740 C CD . LYS A 1 100 ? 5.497 -10.046 57.250 1.00 23.52 ? 100 LYS A CD 1 ATOM 741 C CE . LYS A 1 100 ? 6.059 -8.787 57.937 1.00 29.85 ? 100 LYS A CE 1 ATOM 742 N NZ . LYS A 1 100 ? 7.340 -8.971 58.700 1.00 31.96 ? 100 LYS A NZ 1 ATOM 743 N N . LEU A 1 101 ? 3.960 -14.819 58.681 1.00 20.07 ? 101 LEU A N 1 ATOM 744 C CA . LEU A 1 101 ? 4.735 -15.814 59.402 1.00 20.35 ? 101 LEU A CA 1 ATOM 745 C C . LEU A 1 101 ? 6.129 -15.804 58.769 1.00 20.74 ? 101 LEU A C 1 ATOM 746 O O . LEU A 1 101 ? 6.273 -15.966 57.566 1.00 19.85 ? 101 LEU A O 1 ATOM 747 C CB . LEU A 1 101 ? 4.064 -17.189 59.299 1.00 19.29 ? 101 LEU A CB 1 ATOM 748 C CG . LEU A 1 101 ? 2.678 -17.174 59.988 1.00 18.53 ? 101 LEU A CG 1 ATOM 749 C CD1 . LEU A 1 101 ? 1.811 -18.274 59.472 1.00 19.09 ? 101 LEU A CD1 1 ATOM 750 C CD2 . LEU A 1 101 ? 2.801 -17.256 61.527 1.00 15.15 ? 101 LEU A CD2 1 ATOM 751 N N . THR A 1 102 ? 7.143 -15.534 59.567 1.00 20.92 ? 102 THR A N 1 ATOM 752 C CA . THR A 1 102 ? 8.476 -15.402 59.009 1.00 22.18 ? 102 THR A CA 1 ATOM 753 C C . THR A 1 102 ? 9.378 -16.253 59.887 1.00 22.25 ? 102 THR A C 1 ATOM 754 O O . THR A 1 102 ? 8.955 -16.740 60.922 1.00 21.97 ? 102 THR A O 1 ATOM 755 C CB . THR A 1 102 ? 8.931 -13.912 58.956 1.00 22.04 ? 102 THR A CB 1 ATOM 756 O OG1 . THR A 1 102 ? 8.949 -13.372 60.274 1.00 22.07 ? 102 THR A OG1 1 ATOM 757 C CG2 . THR A 1 102 ? 7.956 -13.056 58.140 1.00 23.48 ? 102 THR A CG2 1 ATOM 758 N N . ASP A 1 103 ? 10.601 -16.475 59.449 1.00 23.82 ? 103 ASP A N 1 ATOM 759 C CA . ASP A 1 103 ? 11.575 -17.194 60.252 1.00 24.74 ? 103 ASP A CA 1 ATOM 760 C C . ASP A 1 103 ? 12.127 -16.181 61.241 1.00 25.48 ? 103 ASP A C 1 ATOM 761 O O . ASP A 1 103 ? 12.598 -15.127 60.855 1.00 25.20 ? 103 ASP A O 1 ATOM 762 C CB . ASP A 1 103 ? 12.677 -17.748 59.343 1.00 24.74 ? 103 ASP A CB 1 ATOM 763 C CG . ASP A 1 103 ? 13.703 -18.593 60.091 1.00 26.28 ? 103 ASP A CG 1 ATOM 764 O OD1 . ASP A 1 103 ? 13.725 -18.566 61.339 1.00 25.59 ? 103 ASP A OD1 1 ATOM 765 O OD2 . ASP A 1 103 ? 14.504 -19.271 59.411 1.00 27.92 ? 103 ASP A OD2 1 ATOM 766 N N . GLN A 1 104 ? 12.049 -16.489 62.527 1.00 27.64 ? 104 GLN A N 1 ATOM 767 C CA . GLN A 1 104 ? 12.474 -15.533 63.548 1.00 30.20 ? 104 GLN A CA 1 ATOM 768 C C . GLN A 1 104 ? 13.944 -15.124 63.480 1.00 31.72 ? 104 GLN A C 1 ATOM 769 O O . GLN A 1 104 ? 14.299 -13.979 63.812 1.00 32.31 ? 104 GLN A O 1 ATOM 770 C CB . GLN A 1 104 ? 12.146 -16.063 64.936 1.00 30.23 ? 104 GLN A CB 1 ATOM 771 C CG . GLN A 1 104 ? 11.807 -14.964 65.877 1.00 32.38 ? 104 GLN A CG 1 ATOM 772 C CD . GLN A 1 104 ? 11.535 -15.447 67.260 1.00 35.94 ? 104 GLN A CD 1 ATOM 773 O OE1 . GLN A 1 104 ? 11.567 -16.657 67.547 1.00 35.96 ? 104 GLN A OE1 1 ATOM 774 N NE2 . GLN A 1 104 ? 11.255 -14.498 68.153 1.00 38.36 ? 104 GLN A NE2 1 ATOM 775 N N . THR A 1 105 ? 14.794 -16.047 63.031 1.00 33.42 ? 105 THR A N 1 ATOM 776 C CA . THR A 1 105 ? 16.246 -15.835 63.081 1.00 34.76 ? 105 THR A CA 1 ATOM 777 C C . THR A 1 105 ? 16.927 -15.786 61.707 1.00 35.14 ? 105 THR A C 1 ATOM 778 O O . THR A 1 105 ? 18.156 -15.818 61.626 1.00 36.24 ? 105 THR A O 1 ATOM 779 C CB . THR A 1 105 ? 16.937 -16.910 63.943 1.00 34.85 ? 105 THR A CB 1 ATOM 780 O OG1 . THR A 1 105 ? 16.670 -18.203 63.394 1.00 36.15 ? 105 THR A OG1 1 ATOM 781 C CG2 . THR A 1 105 ? 16.455 -16.865 65.393 1.00 35.96 ? 105 THR A CG2 1 ATOM 782 N N . ASN A 1 106 ? 16.137 -15.716 60.634 1.00 34.62 ? 106 ASN A N 1 ATOM 783 C CA . ASN A 1 106 ? 16.665 -15.654 59.270 1.00 34.11 ? 106 ASN A CA 1 ATOM 784 C C . ASN A 1 106 ? 15.729 -14.857 58.357 1.00 33.15 ? 106 ASN A C 1 ATOM 785 O O . ASN A 1 106 ? 14.519 -15.081 58.354 1.00 32.46 ? 106 ASN A O 1 ATOM 786 C CB . ASN A 1 106 ? 16.858 -17.067 58.680 1.00 34.10 ? 106 ASN A CB 1 ATOM 787 C CG . ASN A 1 106 ? 17.912 -17.898 59.420 1.00 36.32 ? 106 ASN A CG 1 ATOM 788 O OD1 . ASN A 1 106 ? 17.614 -18.992 59.922 1.00 34.77 ? 106 ASN A OD1 1 ATOM 789 N ND2 . ASN A 1 106 ? 19.153 -17.390 59.480 1.00 37.06 ? 106 ASN A ND2 1 ATOM 790 N N . ASN A 1 107 ? 16.302 -13.933 57.595 1.00 32.57 ? 107 ASN A N 1 ATOM 791 C CA . ASN A 1 107 ? 15.594 -13.180 56.558 1.00 31.72 ? 107 ASN A CA 1 ATOM 792 C C . ASN A 1 107 ? 15.195 -14.115 55.405 1.00 29.96 ? 107 ASN A C 1 ATOM 793 O O . ASN A 1 107 ? 15.992 -14.909 54.947 1.00 30.55 ? 107 ASN A O 1 ATOM 794 C CB . ASN A 1 107 ? 16.488 -12.049 56.025 1.00 32.58 ? 107 ASN A CB 1 ATOM 795 C CG . ASN A 1 107 ? 16.481 -10.777 56.903 1.00 35.56 ? 107 ASN A CG 1 ATOM 796 O OD1 . ASN A 1 107 ? 17.396 -9.948 56.796 1.00 40.56 ? 107 ASN A OD1 1 ATOM 797 N ND2 . ASN A 1 107 ? 15.448 -10.595 57.724 1.00 38.34 ? 107 ASN A ND2 1 ATOM 798 N N . ARG A 1 108 ? 13.949 -14.070 54.954 1.00 27.43 ? 108 ARG A N 1 ATOM 799 C CA . ARG A 1 108 ? 13.552 -14.925 53.827 1.00 24.20 ? 108 ARG A CA 1 ATOM 800 C C . ARG A 1 108 ? 13.079 -14.064 52.667 1.00 23.57 ? 108 ARG A C 1 ATOM 801 O O . ARG A 1 108 ? 12.845 -12.868 52.850 1.00 23.05 ? 108 ARG A O 1 ATOM 802 C CB . ARG A 1 108 ? 12.491 -15.948 54.251 1.00 24.40 ? 108 ARG A CB 1 ATOM 803 C CG . ARG A 1 108 ? 12.933 -16.880 55.383 1.00 20.79 ? 108 ARG A CG 1 ATOM 804 C CD . ARG A 1 108 ? 11.839 -17.886 55.752 1.00 22.24 ? 108 ARG A CD 1 ATOM 805 N NE . ARG A 1 108 ? 11.269 -18.508 54.567 1.00 17.58 ? 108 ARG A NE 1 ATOM 806 C CZ . ARG A 1 108 ? 11.702 -19.643 54.036 1.00 20.28 ? 108 ARG A CZ 1 ATOM 807 N NH1 . ARG A 1 108 ? 12.696 -20.333 54.604 1.00 20.38 ? 108 ARG A NH1 1 ATOM 808 N NH2 . ARG A 1 108 ? 11.139 -20.101 52.942 1.00 16.99 ? 108 ARG A NH2 1 ATOM 809 N N . PHE A 1 109 ? 12.977 -14.646 51.469 1.00 22.13 ? 109 PHE A N 1 ATOM 810 C CA . PHE A 1 109 ? 12.546 -13.886 50.325 1.00 20.83 ? 109 PHE A CA 1 ATOM 811 C C . PHE A 1 109 ? 11.114 -13.376 50.552 1.00 20.83 ? 109 PHE A C 1 ATOM 812 O O . PHE A 1 109 ? 10.247 -14.135 50.990 1.00 19.72 ? 109 PHE A O 1 ATOM 813 C CB . PHE A 1 109 ? 12.584 -14.701 49.027 1.00 20.32 ? 109 PHE A CB 1 ATOM 814 C CG . PHE A 1 109 ? 11.966 -13.962 47.861 1.00 19.32 ? 109 PHE A CG 1 ATOM 815 C CD1 . PHE A 1 109 ? 12.697 -13.012 47.166 1.00 18.34 ? 109 PHE A CD1 1 ATOM 816 C CD2 . PHE A 1 109 ? 10.638 -14.172 47.509 1.00 17.54 ? 109 PHE A CD2 1 ATOM 817 C CE1 . PHE A 1 109 ? 12.137 -12.296 46.121 1.00 19.44 ? 109 PHE A CE1 1 ATOM 818 C CE2 . PHE A 1 109 ? 10.068 -13.468 46.468 1.00 17.60 ? 109 PHE A CE2 1 ATOM 819 C CZ . PHE A 1 109 ? 10.808 -12.534 45.764 1.00 19.11 ? 109 PHE A CZ 1 ATOM 820 N N . GLU A 1 110 ? 10.897 -12.094 50.278 1.00 21.18 ? 110 GLU A N 1 ATOM 821 C CA . GLU A 1 110 ? 9.560 -11.484 50.352 1.00 23.29 ? 110 GLU A CA 1 ATOM 822 C C . GLU A 1 110 ? 9.347 -10.716 49.062 1.00 22.63 ? 110 GLU A C 1 ATOM 823 O O . GLU A 1 110 ? 10.263 -10.031 48.572 1.00 21.61 ? 110 GLU A O 1 ATOM 824 C CB . GLU A 1 110 ? 9.454 -10.539 51.554 1.00 23.37 ? 110 GLU A CB 1 ATOM 825 C CG . GLU A 1 110 ? 9.634 -11.205 52.907 1.00 26.10 ? 110 GLU A CG 1 ATOM 826 C CD . GLU A 1 110 ? 9.529 -10.213 54.055 1.00 28.00 ? 110 GLU A CD 1 ATOM 827 O OE1 . GLU A 1 110 ? 8.425 -9.643 54.262 1.00 33.30 ? 110 GLU A OE1 1 ATOM 828 O OE2 . GLU A 1 110 ? 10.551 -10.009 54.753 1.00 33.61 ? 110 GLU A OE2 1 ATOM 829 N N . VAL A 1 111 ? 8.136 -10.821 48.506 1.00 22.30 ? 111 VAL A N 1 ATOM 830 C CA . VAL A 1 111 ? 7.847 -10.222 47.212 1.00 21.67 ? 111 VAL A CA 1 ATOM 831 C C . VAL A 1 111 ? 8.149 -8.738 47.263 1.00 23.41 ? 111 VAL A C 1 ATOM 832 O O . VAL A 1 111 ? 7.605 -8.047 48.104 1.00 23.64 ? 111 VAL A O 1 ATOM 833 C CB . VAL A 1 111 ? 6.369 -10.412 46.825 1.00 21.52 ? 111 VAL A CB 1 ATOM 834 C CG1 . VAL A 1 111 ? 6.091 -9.782 45.496 1.00 17.00 ? 111 VAL A CG1 1 ATOM 835 C CG2 . VAL A 1 111 ? 6.021 -11.895 46.838 1.00 19.02 ? 111 VAL A CG2 1 ATOM 836 N N . PRO A 1 112 ? 9.019 -8.249 46.360 1.00 24.68 ? 112 PRO A N 1 ATOM 837 C CA . PRO A 1 112 ? 9.346 -6.832 46.276 1.00 25.56 ? 112 PRO A CA 1 ATOM 838 C C . PRO A 1 112 ? 8.297 -6.064 45.445 1.00 26.65 ? 112 PRO A C 1 ATOM 839 O O . PRO A 1 112 ? 8.639 -5.467 44.438 1.00 26.45 ? 112 PRO A O 1 ATOM 840 C CB . PRO A 1 112 ? 10.722 -6.831 45.600 1.00 25.57 ? 112 PRO A CB 1 ATOM 841 C CG . PRO A 1 112 ? 10.819 -8.103 44.868 1.00 25.17 ? 112 PRO A CG 1 ATOM 842 C CD . PRO A 1 112 ? 9.743 -9.043 45.346 1.00 25.02 ? 112 PRO A CD 1 ATOM 843 N N . HIS A 1 113 ? 7.031 -6.102 45.880 1.00 26.88 ? 113 HIS A N 1 ATOM 844 C CA . HIS A 1 113 ? 5.911 -5.512 45.129 1.00 28.07 ? 113 HIS A CA 1 ATOM 845 C C . HIS A 1 113 ? 6.077 -4.002 44.954 1.00 29.08 ? 113 HIS A C 1 ATOM 846 O O . HIS A 1 113 ? 6.473 -3.302 45.900 1.00 29.65 ? 113 HIS A O 1 ATOM 847 C CB . HIS A 1 113 ? 4.589 -5.796 45.842 1.00 27.28 ? 113 HIS A CB 1 ATOM 848 C CG . HIS A 1 113 ? 3.398 -5.850 44.923 1.00 28.31 ? 113 HIS A CG 1 ATOM 849 N ND1 . HIS A 1 113 ? 2.595 -4.756 44.681 1.00 28.07 ? 113 HIS A ND1 1 ATOM 850 C CD2 . HIS A 1 113 ? 2.874 -6.868 44.199 1.00 25.97 ? 113 HIS A CD2 1 ATOM 851 C CE1 . HIS A 1 113 ? 1.631 -5.095 43.840 1.00 28.51 ? 113 HIS A CE1 1 ATOM 852 N NE2 . HIS A 1 113 ? 1.773 -6.374 43.538 1.00 27.18 ? 113 HIS A NE2 1 ATOM 853 N N . GLU A 1 114 ? 5.765 -3.509 43.758 1.00 30.99 ? 114 GLU A N 1 ATOM 854 C CA . GLU A 1 114 ? 5.945 -2.083 43.408 1.00 32.28 ? 114 GLU A CA 1 ATOM 855 C C . GLU A 1 114 ? 4.941 -1.182 44.137 1.00 32.87 ? 114 GLU A C 1 ATOM 856 O O . GLU A 1 114 ? 5.296 -0.091 44.601 1.00 33.44 ? 114 GLU A O 1 ATOM 857 C CB . GLU A 1 114 ? 5.866 -1.875 41.880 1.00 32.37 ? 114 GLU A CB 1 ATOM 858 C CG . GLU A 1 114 ? 6.118 -0.440 41.359 1.00 32.76 ? 114 GLU A CG 1 ATOM 859 C CD . GLU A 1 114 ? 4.855 0.434 41.173 1.00 35.91 ? 114 GLU A CD 1 ATOM 860 O OE1 . GLU A 1 114 ? 3.702 0.038 41.511 1.00 34.46 ? 114 GLU A OE1 1 ATOM 861 O OE2 . GLU A 1 114 ? 5.037 1.557 40.659 1.00 38.11 ? 114 GLU A OE2 1 ATOM 862 N N . HIS A 1 115 ? 3.694 -1.643 44.249 1.00 33.23 ? 115 HIS A N 1 ATOM 863 C CA . HIS A 1 115 ? 2.647 -0.832 44.874 1.00 33.42 ? 115 HIS A CA 1 ATOM 864 C C . HIS A 1 115 ? 2.603 -0.977 46.396 1.00 33.69 ? 115 HIS A C 1 ATOM 865 O O . HIS A 1 115 ? 2.675 0.027 47.119 1.00 33.89 ? 115 HIS A O 1 ATOM 866 C CB . HIS A 1 115 ? 1.276 -1.123 44.256 1.00 33.64 ? 115 HIS A CB 1 ATOM 867 C CG . HIS A 1 115 ? 0.223 -0.128 44.637 1.00 34.02 ? 115 HIS A CG 1 ATOM 868 N ND1 . HIS A 1 115 ? 0.060 1.070 43.977 1.00 35.30 ? 115 HIS A ND1 1 ATOM 869 C CD2 . HIS A 1 115 ? -0.712 -0.146 45.615 1.00 34.36 ? 115 HIS A CD2 1 ATOM 870 C CE1 . HIS A 1 115 ? -0.934 1.747 44.527 1.00 35.19 ? 115 HIS A CE1 1 ATOM 871 N NE2 . HIS A 1 115 ? -1.421 1.031 45.524 1.00 35.15 ? 115 HIS A NE2 1 ATOM 872 N N . VAL A 1 116 ? 2.508 -2.216 46.879 1.00 33.90 ? 116 VAL A N 1 ATOM 873 C CA . VAL A 1 116 ? 2.329 -2.480 48.303 1.00 34.60 ? 116 VAL A CA 1 ATOM 874 C C . VAL A 1 116 ? 3.508 -1.974 49.124 1.00 35.47 ? 116 VAL A C 1 ATOM 875 O O . VAL A 1 116 ? 4.667 -2.253 48.819 1.00 35.45 ? 116 VAL A O 1 ATOM 876 C CB . VAL A 1 116 ? 2.061 -3.975 48.591 1.00 34.53 ? 116 VAL A CB 1 ATOM 877 C CG1 . VAL A 1 116 ? 2.090 -4.269 50.090 1.00 34.49 ? 116 VAL A CG1 1 ATOM 878 C CG2 . VAL A 1 116 ? 0.728 -4.372 48.019 1.00 33.53 ? 116 VAL A CG2 1 ATOM 879 N N . GLN A 1 117 ? 3.190 -1.195 50.154 1.00 36.61 ? 117 GLN A N 1 ATOM 880 C CA . GLN A 1 117 ? 4.203 -0.659 51.054 1.00 37.78 ? 117 GLN A CA 1 ATOM 881 C C . GLN A 1 117 ? 4.126 -1.355 52.394 1.00 37.71 ? 117 GLN A C 1 ATOM 882 O O . GLN A 1 117 ? 3.046 -1.748 52.852 1.00 37.57 ? 117 GLN A O 1 ATOM 883 C CB . GLN A 1 117 ? 3.998 0.835 51.282 1.00 37.48 ? 117 GLN A CB 1 ATOM 884 C CG . GLN A 1 117 ? 4.361 1.729 50.137 1.00 40.57 ? 117 GLN A CG 1 ATOM 885 C CD . GLN A 1 117 ? 4.433 3.175 50.584 1.00 44.09 ? 117 GLN A CD 1 ATOM 886 O OE1 . GLN A 1 117 ? 3.405 3.803 50.873 1.00 47.49 ? 117 GLN A OE1 1 ATOM 887 N NE2 . GLN A 1 117 ? 5.652 3.705 50.681 1.00 44.39 ? 117 GLN A NE2 1 ATOM 888 N N . SER A 1 118 ? 5.279 -1.474 53.036 1.00 38.34 ? 118 SER A N 1 ATOM 889 C CA . SER A 1 118 ? 5.330 -1.892 54.435 1.00 38.79 ? 118 SER A CA 1 ATOM 890 C C . SER A 1 118 ? 4.447 -0.977 55.288 1.00 38.15 ? 118 SER A C 1 ATOM 891 O O . SER A 1 118 ? 4.228 0.202 54.972 1.00 38.11 ? 118 SER A O 1 ATOM 892 C CB . SER A 1 118 ? 6.770 -1.859 54.944 1.00 39.05 ? 118 SER A CB 1 ATOM 893 O OG . SER A 1 118 ? 7.382 -0.634 54.563 1.00 41.16 ? 118 SER A OG 1 ATOM 894 N N . PHE A 1 119 ? 3.931 -1.534 56.370 1.00 37.66 ? 119 PHE A N 1 ATOM 895 C CA . PHE A 1 119 ? 3.018 -0.798 57.205 1.00 37.22 ? 119 PHE A CA 1 ATOM 896 C C . PHE A 1 119 ? 3.750 -0.163 58.370 1.00 37.52 ? 119 PHE A C 1 ATOM 897 O O . PHE A 1 119 ? 4.411 -0.850 59.147 1.00 37.71 ? 119 PHE A O 1 ATOM 898 C CB . PHE A 1 119 ? 1.927 -1.723 57.714 1.00 36.47 ? 119 PHE A CB 1 ATOM 899 C CG . PHE A 1 119 ? 0.874 -1.037 58.501 1.00 33.73 ? 119 PHE A CG 1 ATOM 900 C CD1 . PHE A 1 119 ? -0.048 -0.202 57.876 1.00 33.31 ? 119 PHE A CD1 1 ATOM 901 C CD2 . PHE A 1 119 ? 0.770 -1.250 59.862 1.00 33.33 ? 119 PHE A CD2 1 ATOM 902 C CE1 . PHE A 1 119 ? -1.043 0.420 58.603 1.00 29.64 ? 119 PHE A CE1 1 ATOM 903 C CE2 . PHE A 1 119 ? -0.227 -0.624 60.597 1.00 33.14 ? 119 PHE A CE2 1 ATOM 904 C CZ . PHE A 1 119 ? -1.135 0.213 59.955 1.00 32.48 ? 119 PHE A CZ 1 ATOM 905 N N . SER A 1 120 ? 3.631 1.157 58.457 1.00 38.03 ? 120 SER A N 1 ATOM 906 C CA . SER A 1 120 ? 4.045 1.922 59.627 1.00 38.60 ? 120 SER A CA 1 ATOM 907 C C . SER A 1 120 ? 2.860 2.792 60.001 1.00 38.36 ? 120 SER A C 1 ATOM 908 O O . SER A 1 120 ? 2.779 3.963 59.644 1.00 39.60 ? 120 SER A O 1 ATOM 909 C CB . SER A 1 120 ? 5.289 2.778 59.345 1.00 38.72 ? 120 SER A CB 1 ATOM 910 O OG . SER A 1 120 ? 5.024 3.774 58.364 1.00 39.80 ? 120 SER A OG 1 ATOM 911 N N . GLY A 1 121 ? 1.902 2.186 60.669 1.00 37.79 ? 121 GLY A N 1 ATOM 912 C CA . GLY A 1 121 ? 0.807 2.935 61.239 1.00 36.71 ? 121 GLY A CA 1 ATOM 913 C C . GLY A 1 121 ? 0.529 2.384 62.617 1.00 35.82 ? 121 GLY A C 1 ATOM 914 O O . GLY A 1 121 ? 1.236 1.482 63.103 1.00 35.38 ? 121 GLY A O 1 ATOM 915 N N . ASN A 1 122 ? -0.478 2.971 63.255 1.00 34.88 ? 122 ASN A N 1 ATOM 916 C CA . ASN A 1 122 ? -1.099 2.407 64.427 1.00 34.08 ? 122 ASN A CA 1 ATOM 917 C C . ASN A 1 122 ? -2.267 1.522 64.005 1.00 31.92 ? 122 ASN A C 1 ATOM 918 O O . ASN A 1 122 ? -2.890 1.786 62.989 1.00 32.15 ? 122 ASN A O 1 ATOM 919 C CB . ASN A 1 122 ? -1.609 3.533 65.343 1.00 35.17 ? 122 ASN A CB 1 ATOM 920 C CG . ASN A 1 122 ? -0.483 4.256 66.060 1.00 37.35 ? 122 ASN A CG 1 ATOM 921 O OD1 . ASN A 1 122 ? 0.684 3.881 65.942 1.00 39.92 ? 122 ASN A OD1 1 ATOM 922 N ND2 . ASN A 1 122 ? -0.831 5.293 66.820 1.00 40.91 ? 122 ASN A ND2 1 ATOM 923 N N . ALA A 1 123 ? -2.562 0.496 64.793 1.00 29.72 ? 123 ALA A N 1 ATOM 924 C CA . ALA A 1 123 ? -3.755 -0.313 64.611 1.00 28.11 ? 123 ALA A CA 1 ATOM 925 C C . ALA A 1 123 ? -4.952 0.590 64.319 1.00 27.77 ? 123 ALA A C 1 ATOM 926 O O . ALA A 1 123 ? -5.148 1.615 64.981 1.00 26.65 ? 123 ALA A O 1 ATOM 927 C CB . ALA A 1 123 ? -4.010 -1.132 65.848 1.00 28.39 ? 123 ALA A CB 1 ATOM 928 N N . ALA A 1 124 ? -5.729 0.217 63.306 1.00 26.50 ? 124 ALA A N 1 ATOM 929 C CA . ALA A 1 124 ? -6.869 0.999 62.897 1.00 26.13 ? 124 ALA A CA 1 ATOM 930 C C . ALA A 1 124 ? -7.940 0.895 63.956 1.00 25.91 ? 124 ALA A C 1 ATOM 931 O O . ALA A 1 124 ? -8.000 -0.085 64.696 1.00 25.96 ? 124 ALA A O 1 ATOM 932 C CB . ALA A 1 124 ? -7.400 0.496 61.599 1.00 25.65 ? 124 ALA A CB 1 ATOM 933 N N . ALA A 1 125 ? -8.786 1.909 64.009 1.00 26.24 ? 125 ALA A N 1 ATOM 934 C CA . ALA A 1 125 ? -9.923 1.919 64.905 1.00 26.53 ? 125 ALA A CA 1 ATOM 935 C C . ALA A 1 125 ? -11.130 1.325 64.203 1.00 26.89 ? 125 ALA A C 1 ATOM 936 O O . ALA A 1 125 ? -11.118 1.140 62.972 1.00 27.76 ? 125 ALA A O 1 ATOM 937 C CB . ALA A 1 125 ? -10.213 3.336 65.328 1.00 27.07 ? 125 ALA A CB 1 ATOM 938 N N . SER A 1 126 ? -12.177 1.047 64.982 1.00 26.89 ? 126 SER A N 1 ATOM 939 C CA . SER A 1 126 ? -13.485 0.606 64.471 1.00 26.51 ? 126 SER A CA 1 ATOM 940 C C . SER A 1 126 ? -13.371 -0.560 63.501 1.00 25.96 ? 126 SER A C 1 ATOM 941 O O . SER A 1 126 ? -13.842 -0.490 62.357 1.00 27.35 ? 126 SER A O 1 ATOM 942 C CB . SER A 1 126 ? -14.230 1.765 63.811 1.00 27.00 ? 126 SER A CB 1 ATOM 943 O OG . SER A 1 126 ? -14.098 2.941 64.588 1.00 29.65 ? 126 SER A OG 1 ATOM 944 N N . LEU A 1 127 ? -12.760 -1.640 63.962 1.00 24.62 ? 127 LEU A N 1 ATOM 945 C CA . LEU A 1 127 ? -12.514 -2.820 63.129 1.00 22.79 ? 127 LEU A CA 1 ATOM 946 C C . LEU A 1 127 ? -13.803 -3.592 62.881 1.00 22.40 ? 127 LEU A C 1 ATOM 947 O O . LEU A 1 127 ? -14.608 -3.787 63.805 1.00 21.98 ? 127 LEU A O 1 ATOM 948 C CB . LEU A 1 127 ? -11.503 -3.740 63.820 1.00 22.33 ? 127 LEU A CB 1 ATOM 949 C CG . LEU A 1 127 ? -10.106 -3.187 64.146 1.00 20.85 ? 127 LEU A CG 1 ATOM 950 C CD1 . LEU A 1 127 ? -9.273 -4.253 64.837 1.00 20.88 ? 127 LEU A CD1 1 ATOM 951 C CD2 . LEU A 1 127 ? -9.431 -2.713 62.883 1.00 17.24 ? 127 LEU A CD2 1 ATOM 952 N N . THR A 1 128 ? -13.987 -4.049 61.640 1.00 21.18 ? 128 THR A N 1 ATOM 953 C CA . THR A 1 128 ? -15.138 -4.868 61.274 1.00 20.27 ? 128 THR A CA 1 ATOM 954 C C . THR A 1 128 ? -14.834 -6.332 61.536 1.00 19.46 ? 128 THR A C 1 ATOM 955 O O . THR A 1 128 ? -15.688 -7.180 61.342 1.00 17.84 ? 128 THR A O 1 ATOM 956 C CB . THR A 1 128 ? -15.503 -4.695 59.769 1.00 20.61 ? 128 THR A CB 1 ATOM 957 O OG1 . THR A 1 128 ? -14.461 -5.231 58.958 1.00 22.09 ? 128 THR A OG1 1 ATOM 958 C CG2 . THR A 1 128 ? -15.691 -3.233 59.420 1.00 21.22 ? 128 THR A CG2 1 ATOM 959 N N . TYR A 1 129 ? -13.586 -6.624 61.934 1.00 18.03 ? 129 TYR A N 1 ATOM 960 C CA . TYR A 1 129 ? -13.144 -7.990 62.216 1.00 17.58 ? 129 TYR A CA 1 ATOM 961 C C . TYR A 1 129 ? -12.496 -8.121 63.626 1.00 17.15 ? 129 TYR A C 1 ATOM 962 O O . TYR A 1 129 ? -12.074 -7.135 64.222 1.00 15.02 ? 129 TYR A O 1 ATOM 963 C CB . TYR A 1 129 ? -12.161 -8.472 61.141 1.00 17.10 ? 129 TYR A CB 1 ATOM 964 C CG . TYR A 1 129 ? -10.931 -7.618 61.063 1.00 14.58 ? 129 TYR A CG 1 ATOM 965 C CD1 . TYR A 1 129 ? -9.791 -7.911 61.813 1.00 16.19 ? 129 TYR A CD1 1 ATOM 966 C CD2 . TYR A 1 129 ? -10.897 -6.528 60.227 1.00 13.74 ? 129 TYR A CD2 1 ATOM 967 C CE1 . TYR A 1 129 ? -8.656 -7.088 61.727 1.00 13.83 ? 129 TYR A CE1 1 ATOM 968 C CE2 . TYR A 1 129 ? -9.815 -5.714 60.160 1.00 13.93 ? 129 TYR A CE2 1 ATOM 969 C CZ . TYR A 1 129 ? -8.678 -6.018 60.887 1.00 12.93 ? 129 TYR A CZ 1 ATOM 970 O OH . TYR A 1 129 ? -7.626 -5.151 60.792 1.00 14.73 ? 129 TYR A OH 1 ATOM 971 N N . GLN A 1 130 ? -12.455 -9.347 64.132 1.00 17.48 ? 130 GLN A N 1 ATOM 972 C CA . GLN A 1 130 ? -11.718 -9.687 65.350 1.00 19.48 ? 130 GLN A CA 1 ATOM 973 C C . GLN A 1 130 ? -10.720 -10.841 65.035 1.00 18.21 ? 130 GLN A C 1 ATOM 974 O O . GLN A 1 130 ? -10.991 -11.689 64.196 1.00 18.56 ? 130 GLN A O 1 ATOM 975 C CB . GLN A 1 130 ? -12.703 -10.073 66.449 1.00 19.19 ? 130 GLN A CB 1 ATOM 976 C CG . GLN A 1 130 ? -12.093 -10.321 67.833 1.00 22.23 ? 130 GLN A CG 1 ATOM 977 C CD . GLN A 1 130 ? -13.152 -10.636 68.893 1.00 24.58 ? 130 GLN A CD 1 ATOM 978 O OE1 . GLN A 1 130 ? -14.364 -10.671 68.607 1.00 30.83 ? 130 GLN A OE1 1 ATOM 979 N NE2 . GLN A 1 130 ? -12.702 -10.848 70.126 1.00 28.54 ? 130 GLN A NE2 1 ATOM 980 N N . VAL A 1 131 ? -9.574 -10.837 65.700 1.00 17.79 ? 131 VAL A N 1 ATOM 981 C CA . VAL A 1 131 ? -8.528 -11.844 65.526 1.00 17.06 ? 131 VAL A CA 1 ATOM 982 C C . VAL A 1 131 ? -8.340 -12.619 66.828 1.00 17.78 ? 131 VAL A C 1 ATOM 983 O O . VAL A 1 131 ? -8.183 -12.040 67.902 1.00 17.48 ? 131 VAL A O 1 ATOM 984 C CB . VAL A 1 131 ? -7.214 -11.190 65.115 1.00 16.89 ? 131 VAL A CB 1 ATOM 985 C CG1 . VAL A 1 131 ? -6.095 -12.258 64.841 1.00 15.32 ? 131 VAL A CG1 1 ATOM 986 C CG2 . VAL A 1 131 ? -7.443 -10.287 63.906 1.00 15.05 ? 131 VAL A CG2 1 ATOM 987 N N . GLU A 1 132 ? -8.394 -13.937 66.728 1.00 17.89 ? 132 GLU A N 1 ATOM 988 C CA . GLU A 1 132 ? -8.319 -14.816 67.880 1.00 19.24 ? 132 GLU A CA 1 ATOM 989 C C . GLU A 1 132 ? -7.112 -15.720 67.622 1.00 18.76 ? 132 GLU A C 1 ATOM 990 O O . GLU A 1 132 ? -7.028 -16.320 66.560 1.00 18.31 ? 132 GLU A O 1 ATOM 991 C CB . GLU A 1 132 ? -9.591 -15.682 67.953 1.00 19.93 ? 132 GLU A CB 1 ATOM 992 C CG . GLU A 1 132 ? -10.919 -14.887 68.211 1.00 25.52 ? 132 GLU A CG 1 ATOM 993 C CD . GLU A 1 132 ? -11.641 -14.299 66.979 1.00 31.38 ? 132 GLU A CD 1 ATOM 994 O OE1 . GLU A 1 132 ? -11.343 -14.625 65.807 1.00 32.21 ? 132 GLU A OE1 1 ATOM 995 O OE2 . GLU A 1 132 ? -12.577 -13.503 67.210 1.00 35.53 ? 132 GLU A OE2 1 ATOM 996 N N . ILE A 1 133 ? -6.208 -15.819 68.580 1.00 18.03 ? 133 ILE A N 1 ATOM 997 C CA . ILE A 1 133 ? -5.032 -16.694 68.479 1.00 18.48 ? 133 ILE A CA 1 ATOM 998 C C . ILE A 1 133 ? -5.105 -17.783 69.513 1.00 18.93 ? 133 ILE A C 1 ATOM 999 O O . ILE A 1 133 ? -5.385 -17.509 70.658 1.00 18.76 ? 133 ILE A O 1 ATOM 1000 C CB . ILE A 1 133 ? -3.745 -15.890 68.703 1.00 18.02 ? 133 ILE A CB 1 ATOM 1001 C CG1 . ILE A 1 133 ? -3.687 -14.727 67.722 1.00 19.08 ? 133 ILE A CG1 1 ATOM 1002 C CG2 . ILE A 1 133 ? -2.447 -16.797 68.691 1.00 18.32 ? 133 ILE A CG2 1 ATOM 1003 C CD1 . ILE A 1 133 ? -3.714 -15.126 66.260 1.00 20.55 ? 133 ILE A CD1 1 ATOM 1004 N N . SER A 1 134 ? -4.872 -19.023 69.096 1.00 20.62 ? 134 SER A N 1 ATOM 1005 C CA . SER A 1 134 ? -4.805 -20.148 70.002 1.00 22.44 ? 134 SER A CA 1 ATOM 1006 C C . SER A 1 134 ? -3.353 -20.556 70.114 1.00 24.03 ? 134 SER A C 1 ATOM 1007 O O . SER A 1 134 ? -2.591 -20.395 69.164 1.00 24.19 ? 134 SER A O 1 ATOM 1008 C CB . SER A 1 134 ? -5.670 -21.291 69.500 1.00 22.78 ? 134 SER A CB 1 ATOM 1009 O OG . SER A 1 134 ? -7.019 -20.860 69.489 1.00 25.15 ? 134 SER A OG 1 ATOM 1010 N N . ARG A 1 135 ? -2.971 -21.044 71.286 1.00 25.31 ? 135 ARG A N 1 ATOM 1011 C CA . ARG A 1 135 ? -1.571 -21.178 71.656 1.00 26.89 ? 135 ARG A CA 1 ATOM 1012 C C . ARG A 1 135 ? -1.106 -22.600 71.434 1.00 26.80 ? 135 ARG A C 1 ATOM 1013 O O . ARG A 1 135 ? 0.005 -22.827 70.982 1.00 26.40 ? 135 ARG A O 1 ATOM 1014 C CB . ARG A 1 135 ? -1.377 -20.886 73.167 1.00 28.59 ? 135 ARG A CB 1 ATOM 1015 C CG . ARG A 1 135 ? -1.031 -19.476 73.616 1.00 30.94 ? 135 ARG A CG 1 ATOM 1016 C CD . ARG A 1 135 ? -0.129 -19.583 74.874 1.00 35.52 ? 135 ARG A CD 1 ATOM 1017 N NE . ARG A 1 135 ? 0.189 -18.297 75.539 1.00 38.51 ? 135 ARG A NE 1 ATOM 1018 C CZ . ARG A 1 135 ? 0.281 -17.106 74.940 1.00 35.65 ? 135 ARG A CZ 1 ATOM 1019 N NH1 . ARG A 1 135 ? 0.121 -16.974 73.634 1.00 38.51 ? 135 ARG A NH1 1 ATOM 1020 N NH2 . ARG A 1 135 ? 0.570 -16.041 75.653 1.00 36.55 ? 135 ARG A NH2 1 ATOM 1021 N N . GLN A 1 136 ? -1.946 -23.560 71.818 1.00 27.54 ? 136 GLN A N 1 ATOM 1022 C CA . GLN A 1 136 ? -1.509 -24.955 71.941 1.00 27.93 ? 136 GLN A CA 1 ATOM 1023 C C . GLN A 1 136 ? -2.542 -25.927 71.351 1.00 27.61 ? 136 GLN A C 1 ATOM 1024 O O . GLN A 1 136 ? -3.419 -26.412 72.063 1.00 28.61 ? 136 GLN A O 1 ATOM 1025 C CB . GLN A 1 136 ? -1.163 -25.296 73.401 1.00 28.02 ? 136 GLN A CB 1 ATOM 1026 C CG . GLN A 1 136 ? -0.560 -24.137 74.261 1.00 30.42 ? 136 GLN A CG 1 ATOM 1027 C CD . GLN A 1 136 ? 0.938 -23.863 73.998 1.00 36.03 ? 136 GLN A CD 1 ATOM 1028 O OE1 . GLN A 1 136 ? 1.738 -24.793 73.852 1.00 37.15 ? 136 GLN A OE1 1 ATOM 1029 N NE2 . GLN A 1 136 ? 1.319 -22.575 73.966 1.00 35.20 ? 136 GLN A NE2 1 ATOM 1030 N N . PRO A 1 137 ? -2.450 -26.218 70.035 1.00 26.97 ? 137 PRO A N 1 ATOM 1031 C CA . PRO A 1 137 ? -1.438 -25.748 69.086 1.00 26.39 ? 137 PRO A CA 1 ATOM 1032 C C . PRO A 1 137 ? -1.849 -24.414 68.433 1.00 25.47 ? 137 PRO A C 1 ATOM 1033 O O . PRO A 1 137 ? -2.997 -23.975 68.585 1.00 25.56 ? 137 PRO A O 1 ATOM 1034 C CB . PRO A 1 137 ? -1.412 -26.870 68.054 1.00 26.68 ? 137 PRO A CB 1 ATOM 1035 C CG . PRO A 1 137 ? -2.837 -27.384 68.029 1.00 27.32 ? 137 PRO A CG 1 ATOM 1036 C CD . PRO A 1 137 ? -3.455 -27.077 69.373 1.00 26.55 ? 137 PRO A CD 1 ATOM 1037 N N . PHE A 1 138 ? -0.912 -23.784 67.731 1.00 24.02 ? 138 PHE A N 1 ATOM 1038 C CA . PHE A 1 138 ? -1.153 -22.520 67.056 1.00 22.90 ? 138 PHE A CA 1 ATOM 1039 C C . PHE A 1 138 ? -2.299 -22.586 66.046 1.00 22.65 ? 138 PHE A C 1 ATOM 1040 O O . PHE A 1 138 ? -2.371 -23.498 65.218 1.00 22.08 ? 138 PHE A O 1 ATOM 1041 C CB . PHE A 1 138 ? 0.106 -21.995 66.356 1.00 21.29 ? 138 PHE A CB 1 ATOM 1042 C CG . PHE A 1 138 ? -0.152 -20.812 65.457 1.00 21.57 ? 138 PHE A CG 1 ATOM 1043 C CD1 . PHE A 1 138 ? -0.167 -20.960 64.069 1.00 20.64 ? 138 PHE A CD1 1 ATOM 1044 C CD2 . PHE A 1 138 ? -0.406 -19.550 65.999 1.00 19.99 ? 138 PHE A CD2 1 ATOM 1045 C CE1 . PHE A 1 138 ? -0.430 -19.882 63.244 1.00 20.58 ? 138 PHE A CE1 1 ATOM 1046 C CE2 . PHE A 1 138 ? -0.664 -18.465 65.174 1.00 21.76 ? 138 PHE A CE2 1 ATOM 1047 C CZ . PHE A 1 138 ? -0.676 -18.637 63.789 1.00 21.69 ? 138 PHE A CZ 1 ATOM 1048 N N . SER A 1 139 ? -3.192 -21.605 66.135 1.00 22.33 ? 139 SER A N 1 ATOM 1049 C CA . SER A 1 139 ? -4.151 -21.353 65.067 1.00 21.60 ? 139 SER A CA 1 ATOM 1050 C C . SER A 1 139 ? -4.495 -19.867 65.079 1.00 20.88 ? 139 SER A C 1 ATOM 1051 O O . SER A 1 139 ? -4.333 -19.218 66.098 1.00 20.84 ? 139 SER A O 1 ATOM 1052 C CB . SER A 1 139 ? -5.371 -22.286 65.150 1.00 22.28 ? 139 SER A CB 1 ATOM 1053 O OG . SER A 1 139 ? -6.330 -21.825 66.081 1.00 23.90 ? 139 SER A OG 1 ATOM 1054 N N . ILE A 1 140 ? -4.840 -19.321 63.913 1.00 19.95 ? 140 ILE A N 1 ATOM 1055 C CA . ILE A 1 140 ? -5.263 -17.933 63.762 1.00 19.73 ? 140 ILE A CA 1 ATOM 1056 C C . ILE A 1 140 ? -6.663 -17.939 63.177 1.00 19.68 ? 140 ILE A C 1 ATOM 1057 O O . ILE A 1 140 ? -6.933 -18.664 62.230 1.00 18.64 ? 140 ILE A O 1 ATOM 1058 C CB . ILE A 1 140 ? -4.284 -17.080 62.882 1.00 19.60 ? 140 ILE A CB 1 ATOM 1059 C CG1 . ILE A 1 140 ? -4.767 -15.629 62.734 1.00 19.67 ? 140 ILE A CG1 1 ATOM 1060 C CG2 . ILE A 1 140 ? -4.098 -17.682 61.488 1.00 18.66 ? 140 ILE A CG2 1 ATOM 1061 C CD1 . ILE A 1 140 ? -3.609 -14.591 62.533 1.00 20.07 ? 140 ILE A CD1 1 ATOM 1062 N N . LYS A 1 141 ? -7.547 -17.147 63.762 1.00 19.92 ? 141 LYS A N 1 ATOM 1063 C CA . LYS A 1 141 ? -8.946 -17.097 63.343 1.00 20.50 ? 141 LYS A CA 1 ATOM 1064 C C . LYS A 1 141 ? -9.285 -15.628 63.131 1.00 19.99 ? 141 LYS A C 1 ATOM 1065 O O . LYS A 1 141 ? -8.857 -14.766 63.903 1.00 19.14 ? 141 LYS A O 1 ATOM 1066 C CB . LYS A 1 141 ? -9.849 -17.711 64.422 1.00 20.51 ? 141 LYS A CB 1 ATOM 1067 C CG . LYS A 1 141 ? -11.248 -18.109 63.944 1.00 25.73 ? 141 LYS A CG 1 ATOM 1068 C CD . LYS A 1 141 ? -12.314 -18.052 65.052 1.00 27.67 ? 141 LYS A CD 1 ATOM 1069 C CE . LYS A 1 141 ? -12.225 -19.212 66.032 1.00 30.79 ? 141 LYS A CE 1 ATOM 1070 N NZ . LYS A 1 141 ? -13.336 -19.188 67.076 1.00 31.02 ? 141 LYS A NZ 1 ATOM 1071 N N . VAL A 1 142 ? -10.005 -15.334 62.055 1.00 18.88 ? 142 VAL A N 1 ATOM 1072 C CA . VAL A 1 142 ? -10.459 -13.977 61.795 1.00 18.06 ? 142 VAL A CA 1 ATOM 1073 C C . VAL A 1 142 ? -11.969 -14.073 61.690 1.00 18.39 ? 142 VAL A C 1 ATOM 1074 O O . VAL A 1 142 ? -12.502 -14.848 60.904 1.00 17.42 ? 142 VAL A O 1 ATOM 1075 C CB . VAL A 1 142 ? -9.857 -13.335 60.512 1.00 18.25 ? 142 VAL A CB 1 ATOM 1076 C CG1 . VAL A 1 142 ? -10.375 -11.911 60.332 1.00 17.53 ? 142 VAL A CG1 1 ATOM 1077 C CG2 . VAL A 1 142 ? -8.299 -13.324 60.537 1.00 16.45 ? 142 VAL A CG2 1 ATOM 1078 N N . THR A 1 143 ? -12.650 -13.290 62.521 1.00 18.82 ? 143 THR A N 1 ATOM 1079 C CA . THR A 1 143 ? -14.100 -13.329 62.603 1.00 18.80 ? 143 THR A CA 1 ATOM 1080 C C . THR A 1 143 ? -14.711 -11.983 62.205 1.00 18.85 ? 143 THR A C 1 ATOM 1081 O O . THR A 1 143 ? -14.093 -10.939 62.329 1.00 19.92 ? 143 THR A O 1 ATOM 1082 C CB . THR A 1 143 ? -14.581 -13.756 64.003 1.00 18.91 ? 143 THR A CB 1 ATOM 1083 O OG1 . THR A 1 143 ? -13.942 -12.942 65.003 1.00 22.17 ? 143 THR A OG1 1 ATOM 1084 C CG2 . THR A 1 143 ? -14.250 -15.176 64.259 1.00 16.04 ? 143 THR A CG2 1 ATOM 1085 N N . ARG A 1 144 ? -15.908 -12.023 61.651 1.00 18.89 ? 144 ARG A N 1 ATOM 1086 C CA . ARG A 1 144 ? -16.662 -10.811 61.414 1.00 18.05 ? 144 ARG A CA 1 ATOM 1087 C C . ARG A 1 144 ? -17.317 -10.422 62.750 1.00 17.81 ? 144 ARG A C 1 ATOM 1088 O O . ARG A 1 144 ? -17.985 -11.224 63.378 1.00 16.31 ? 144 ARG A O 1 ATOM 1089 C CB . ARG A 1 144 ? -17.705 -11.046 60.312 1.00 18.32 ? 144 ARG A CB 1 ATOM 1090 C CG . ARG A 1 144 ? -18.553 -9.829 60.021 1.00 17.91 ? 144 ARG A CG 1 ATOM 1091 C CD . ARG A 1 144 ? -19.466 -10.059 58.823 1.00 17.99 ? 144 ARG A CD 1 ATOM 1092 N NE . ARG A 1 144 ? -18.737 -10.180 57.571 1.00 19.84 ? 144 ARG A NE 1 ATOM 1093 C CZ . ARG A 1 144 ? -18.274 -9.154 56.861 1.00 16.41 ? 144 ARG A CZ 1 ATOM 1094 N NH1 . ARG A 1 144 ? -18.472 -7.911 57.270 1.00 16.90 ? 144 ARG A NH1 1 ATOM 1095 N NH2 . ARG A 1 144 ? -17.634 -9.382 55.730 1.00 14.99 ? 144 ARG A NH2 1 ATOM 1096 N N . ARG A 1 145 ? -17.063 -9.200 63.194 1.00 18.72 ? 145 ARG A N 1 ATOM 1097 C CA . ARG A 1 145 ? -17.533 -8.687 64.468 1.00 20.25 ? 145 ARG A CA 1 ATOM 1098 C C . ARG A 1 145 ? -19.080 -8.654 64.540 1.00 21.09 ? 145 ARG A C 1 ATOM 1099 O O . ARG A 1 145 ? -19.661 -9.097 65.542 1.00 21.30 ? 145 ARG A O 1 ATOM 1100 C CB . ARG A 1 145 ? -16.956 -7.282 64.642 1.00 20.22 ? 145 ARG A CB 1 ATOM 1101 C CG . ARG A 1 145 ? -16.596 -6.905 66.036 1.00 25.97 ? 145 ARG A CG 1 ATOM 1102 C CD . ARG A 1 145 ? -15.558 -5.790 66.041 1.00 30.65 ? 145 ARG A CD 1 ATOM 1103 N NE . ARG A 1 145 ? -15.662 -4.965 67.234 1.00 34.14 ? 145 ARG A NE 1 ATOM 1104 C CZ . ARG A 1 145 ? -15.899 -3.650 67.256 1.00 35.97 ? 145 ARG A CZ 1 ATOM 1105 N NH1 . ARG A 1 145 ? -16.053 -2.946 66.147 1.00 36.66 ? 145 ARG A NH1 1 ATOM 1106 N NH2 . ARG A 1 145 ? -15.970 -3.025 68.423 1.00 38.50 ? 145 ARG A NH2 1 ATOM 1107 N N . SER A 1 146 ? -19.726 -8.143 63.489 1.00 21.22 ? 146 SER A N 1 ATOM 1108 C CA . SER A 1 146 ? -21.197 -7.977 63.473 1.00 22.58 ? 146 SER A CA 1 ATOM 1109 C C . SER A 1 146 ? -21.907 -9.271 63.871 1.00 23.05 ? 146 SER A C 1 ATOM 1110 O O . SER A 1 146 ? -22.651 -9.271 64.821 1.00 23.88 ? 146 SER A O 1 ATOM 1111 C CB . SER A 1 146 ? -21.711 -7.429 62.130 1.00 22.66 ? 146 SER A CB 1 ATOM 1112 O OG . SER A 1 146 ? -21.337 -8.251 61.028 1.00 22.23 ? 146 SER A OG 1 ATOM 1113 N N . ASN A 1 147 ? -21.583 -10.378 63.210 1.00 23.61 ? 147 ASN A N 1 ATOM 1114 C CA . ASN A 1 147 ? -22.249 -11.662 63.438 1.00 23.51 ? 147 ASN A CA 1 ATOM 1115 C C . ASN A 1 147 ? -21.335 -12.796 63.963 1.00 23.03 ? 147 ASN A C 1 ATOM 1116 O O . ASN A 1 147 ? -21.745 -13.949 64.049 1.00 23.58 ? 147 ASN A O 1 ATOM 1117 C CB . ASN A 1 147 ? -22.984 -12.095 62.164 1.00 23.13 ? 147 ASN A CB 1 ATOM 1118 C CG . ASN A 1 147 ? -22.062 -12.238 60.962 1.00 24.57 ? 147 ASN A CG 1 ATOM 1119 O OD1 . ASN A 1 147 ? -20.820 -12.089 61.063 1.00 21.61 ? 147 ASN A OD1 1 ATOM 1120 N ND2 . ASN A 1 147 ? -22.662 -12.529 59.812 1.00 19.35 ? 147 ASN A ND2 1 ATOM 1121 N N . ASN A 1 148 ? -20.104 -12.456 64.319 1.00 22.10 ? 148 ASN A N 1 ATOM 1122 C CA . ASN A 1 148 ? -19.093 -13.446 64.714 1.00 21.09 ? 148 ASN A CA 1 ATOM 1123 C C . ASN A 1 148 ? -18.961 -14.615 63.742 1.00 19.56 ? 148 ASN A C 1 ATOM 1124 O O . ASN A 1 148 ? -18.692 -15.739 64.160 1.00 20.43 ? 148 ASN A O 1 ATOM 1125 C CB . ASN A 1 148 ? -19.357 -13.963 66.148 1.00 22.19 ? 148 ASN A CB 1 ATOM 1126 C CG . ASN A 1 148 ? -19.008 -12.923 67.231 1.00 23.98 ? 148 ASN A CG 1 ATOM 1127 O OD1 . ASN A 1 148 ? -19.528 -12.979 68.335 1.00 29.73 ? 148 ASN A OD1 1 ATOM 1128 N ND2 . ASN A 1 148 ? -18.117 -12.000 66.914 1.00 23.57 ? 148 ASN A ND2 1 ATOM 1129 N N . ARG A 1 149 ? -19.153 -14.357 62.451 1.00 17.73 ? 149 ARG A N 1 ATOM 1130 C CA . ARG A 1 149 ? -19.000 -15.409 61.431 1.00 16.30 ? 149 ARG A CA 1 ATOM 1131 C C . ARG A 1 149 ? -17.507 -15.664 61.351 1.00 15.28 ? 149 ARG A C 1 ATOM 1132 O O . ARG A 1 149 ? -16.734 -14.744 61.197 1.00 14.83 ? 149 ARG A O 1 ATOM 1133 C CB . ARG A 1 149 ? -19.511 -14.935 60.089 1.00 15.46 ? 149 ARG A CB 1 ATOM 1134 C CG . ARG A 1 149 ? -19.283 -15.884 58.876 1.00 20.91 ? 149 ARG A CG 1 ATOM 1135 C CD . ARG A 1 149 ? -20.473 -16.759 58.600 1.00 27.15 ? 149 ARG A CD 1 ATOM 1136 N NE . ARG A 1 149 ? -21.668 -15.958 58.341 1.00 31.18 ? 149 ARG A NE 1 ATOM 1137 C CZ . ARG A 1 149 ? -22.884 -16.471 58.179 1.00 35.75 ? 149 ARG A CZ 1 ATOM 1138 N NH1 . ARG A 1 149 ? -23.066 -17.794 58.240 1.00 37.21 ? 149 ARG A NH1 1 ATOM 1139 N NH2 . ARG A 1 149 ? -23.916 -15.661 57.958 1.00 35.13 ? 149 ARG A NH2 1 ATOM 1140 N N . VAL A 1 150 ? -17.113 -16.908 61.472 1.00 15.79 ? 150 VAL A N 1 ATOM 1141 C CA . VAL A 1 150 ? -15.700 -17.239 61.352 1.00 15.70 ? 150 VAL A CA 1 ATOM 1142 C C . VAL A 1 150 ? -15.359 -17.175 59.875 1.00 15.47 ? 150 VAL A C 1 ATOM 1143 O O . VAL A 1 150 ? -15.931 -17.921 59.077 1.00 14.09 ? 150 VAL A O 1 ATOM 1144 C CB . VAL A 1 150 ? -15.428 -18.651 61.855 1.00 16.17 ? 150 VAL A CB 1 ATOM 1145 C CG1 . VAL A 1 150 ? -13.949 -19.007 61.583 1.00 17.24 ? 150 VAL A CG1 1 ATOM 1146 C CG2 . VAL A 1 150 ? -15.768 -18.759 63.357 1.00 15.83 ? 150 VAL A CG2 1 ATOM 1147 N N . LEU A 1 151 ? -14.415 -16.305 59.510 1.00 15.63 ? 151 LEU A N 1 ATOM 1148 C CA . LEU A 1 151 ? -14.027 -16.159 58.105 1.00 16.09 ? 151 LEU A CA 1 ATOM 1149 C C . LEU A 1 151 ? -12.744 -16.966 57.738 1.00 17.13 ? 151 LEU A C 1 ATOM 1150 O O . LEU A 1 151 ? -12.789 -17.806 56.856 1.00 17.52 ? 151 LEU A O 1 ATOM 1151 C CB . LEU A 1 151 ? -13.897 -14.673 57.737 1.00 15.05 ? 151 LEU A CB 1 ATOM 1152 C CG . LEU A 1 151 ? -15.100 -13.775 58.066 1.00 14.13 ? 151 LEU A CG 1 ATOM 1153 C CD1 . LEU A 1 151 ? -14.761 -12.350 57.774 1.00 13.10 ? 151 LEU A CD1 1 ATOM 1154 C CD2 . LEU A 1 151 ? -16.351 -14.202 57.306 1.00 12.70 ? 151 LEU A CD2 1 ATOM 1155 N N . PHE A 1 152 ? -11.620 -16.650 58.384 1.00 17.62 ? 152 PHE A N 1 ATOM 1156 C CA . PHE A 1 152 ? -10.341 -17.368 58.263 1.00 18.53 ? 152 PHE A CA 1 ATOM 1157 C C . PHE A 1 152 ? -10.202 -18.164 59.552 1.00 19.29 ? 152 PHE A C 1 ATOM 1158 O O . PHE A 1 152 ? -10.453 -17.630 60.624 1.00 19.20 ? 152 PHE A O 1 ATOM 1159 C CB . PHE A 1 152 ? -9.189 -16.348 58.212 1.00 18.27 ? 152 PHE A CB 1 ATOM 1160 C CG . PHE A 1 152 ? -7.895 -16.879 57.639 1.00 19.60 ? 152 PHE A CG 1 ATOM 1161 C CD1 . PHE A 1 152 ? -7.594 -16.700 56.291 1.00 19.43 ? 152 PHE A CD1 1 ATOM 1162 C CD2 . PHE A 1 152 ? -6.966 -17.541 58.449 1.00 19.04 ? 152 PHE A CD2 1 ATOM 1163 C CE1 . PHE A 1 152 ? -6.373 -17.172 55.748 1.00 19.69 ? 152 PHE A CE1 1 ATOM 1164 C CE2 . PHE A 1 152 ? -5.750 -18.022 57.916 1.00 19.69 ? 152 PHE A CE2 1 ATOM 1165 C CZ . PHE A 1 152 ? -5.461 -17.844 56.560 1.00 18.16 ? 152 PHE A CZ 1 ATOM 1166 N N . ASP A 1 153 ? -9.813 -19.432 59.461 1.00 19.92 ? 153 ASP A N 1 ATOM 1167 C CA . ASP A 1 153 ? -9.617 -20.257 60.643 1.00 20.00 ? 153 ASP A CA 1 ATOM 1168 C C . ASP A 1 153 ? -8.595 -21.316 60.311 1.00 19.32 ? 153 ASP A C 1 ATOM 1169 O O . ASP A 1 153 ? -8.937 -22.333 59.709 1.00 19.20 ? 153 ASP A O 1 ATOM 1170 C CB . ASP A 1 153 ? -10.948 -20.905 61.089 1.00 20.14 ? 153 ASP A CB 1 ATOM 1171 C CG . ASP A 1 153 ? -10.796 -21.788 62.315 1.00 23.22 ? 153 ASP A CG 1 ATOM 1172 O OD1 . ASP A 1 153 ? -9.691 -21.843 62.927 1.00 25.92 ? 153 ASP A OD1 1 ATOM 1173 O OD2 . ASP A 1 153 ? -11.787 -22.466 62.670 1.00 28.57 ? 153 ASP A OD2 1 ATOM 1174 N N . SER A 1 154 ? -7.334 -21.070 60.664 1.00 18.99 ? 154 SER A N 1 ATOM 1175 C CA . SER A 1 154 ? -6.272 -22.040 60.365 1.00 18.89 ? 154 SER A CA 1 ATOM 1176 C C . SER A 1 154 ? -6.348 -23.359 61.152 1.00 19.49 ? 154 SER A C 1 ATOM 1177 O O . SER A 1 154 ? -5.611 -24.303 60.812 1.00 20.26 ? 154 SER A O 1 ATOM 1178 C CB . SER A 1 154 ? -4.885 -21.410 60.528 1.00 19.00 ? 154 SER A CB 1 ATOM 1179 O OG . SER A 1 154 ? -4.654 -21.126 61.883 1.00 18.32 ? 154 SER A OG 1 ATOM 1180 N N . SER A 1 155 ? -7.249 -23.453 62.150 1.00 19.69 ? 155 SER A N 1 ATOM 1181 C CA . SER A 1 155 ? -7.294 -24.601 63.088 1.00 19.36 ? 155 SER A CA 1 ATOM 1182 C C . SER A 1 155 ? -7.672 -25.929 62.462 1.00 18.89 ? 155 SER A C 1 ATOM 1183 O O . SER A 1 155 ? -7.499 -26.981 63.105 1.00 19.13 ? 155 SER A O 1 ATOM 1184 C CB . SER A 1 155 ? -8.215 -24.338 64.299 1.00 19.61 ? 155 SER A CB 1 ATOM 1185 O OG . SER A 1 155 ? -9.595 -24.389 63.917 1.00 22.14 ? 155 SER A OG 1 ATOM 1186 N N . ILE A 1 156 ? -8.188 -25.905 61.230 1.00 17.93 ? 156 ILE A N 1 ATOM 1187 C CA . ILE A 1 156 ? -8.481 -27.159 60.501 1.00 17.03 ? 156 ILE A CA 1 ATOM 1188 C C . ILE A 1 156 ? -7.220 -28.013 60.201 1.00 16.91 ? 156 ILE A C 1 ATOM 1189 O O . ILE A 1 156 ? -7.272 -29.256 60.143 1.00 17.32 ? 156 ILE A O 1 ATOM 1190 C CB . ILE A 1 156 ? -9.290 -26.894 59.199 1.00 17.68 ? 156 ILE A CB 1 ATOM 1191 C CG1 . ILE A 1 156 ? -9.919 -28.184 58.682 1.00 14.82 ? 156 ILE A CG1 1 ATOM 1192 C CG2 . ILE A 1 156 ? -8.431 -26.120 58.148 1.00 16.07 ? 156 ILE A CG2 1 ATOM 1193 C CD1 . ILE A 1 156 ? -11.102 -27.973 57.641 1.00 17.08 ? 156 ILE A CD1 1 ATOM 1194 N N . GLY A 1 157 ? -6.077 -27.363 60.063 1.00 16.43 ? 157 GLY A N 1 ATOM 1195 C CA . GLY A 1 157 ? -4.863 -28.098 59.787 1.00 15.64 ? 157 GLY A CA 1 ATOM 1196 C C . GLY A 1 157 ? -3.641 -27.473 60.421 1.00 15.76 ? 157 GLY A C 1 ATOM 1197 O O . GLY A 1 157 ? -3.715 -26.480 61.140 1.00 14.69 ? 157 GLY A O 1 ATOM 1198 N N . PRO A 1 158 ? -2.488 -28.080 60.180 1.00 16.11 ? 158 PRO A N 1 ATOM 1199 C CA . PRO A 1 158 ? -1.258 -27.556 60.751 1.00 16.08 ? 158 PRO A CA 1 ATOM 1200 C C . PRO A 1 158 ? -0.745 -26.292 60.058 1.00 16.37 ? 158 PRO A C 1 ATOM 1201 O O . PRO A 1 158 ? -1.193 -25.944 58.963 1.00 17.60 ? 158 PRO A O 1 ATOM 1202 C CB . PRO A 1 158 ? -0.280 -28.713 60.525 1.00 16.77 ? 158 PRO A CB 1 ATOM 1203 C CG . PRO A 1 158 ? -0.698 -29.290 59.203 1.00 15.35 ? 158 PRO A CG 1 ATOM 1204 C CD . PRO A 1 158 ? -2.252 -29.287 59.354 1.00 16.93 ? 158 PRO A CD 1 ATOM 1205 N N . LEU A 1 159 ? 0.181 -25.596 60.710 1.00 17.17 ? 159 LEU A N 1 ATOM 1206 C CA . LEU A 1 159 ? 1.116 -24.756 60.026 1.00 16.37 ? 159 LEU A CA 1 ATOM 1207 C C . LEU A 1 159 ? 2.361 -25.584 59.740 1.00 18.54 ? 159 LEU A C 1 ATOM 1208 O O . LEU A 1 159 ? 2.948 -26.164 60.652 1.00 18.23 ? 159 LEU A O 1 ATOM 1209 C CB . LEU A 1 159 ? 1.521 -23.548 60.875 1.00 16.97 ? 159 LEU A CB 1 ATOM 1210 C CG . LEU A 1 159 ? 2.825 -22.817 60.453 1.00 14.25 ? 159 LEU A CG 1 ATOM 1211 C CD1 . LEU A 1 159 ? 2.719 -22.056 59.113 1.00 9.18 ? 159 LEU A CD1 1 ATOM 1212 C CD2 . LEU A 1 159 ? 3.243 -21.858 61.556 1.00 13.69 ? 159 LEU A CD2 1 ATOM 1213 N N . LEU A 1 160 ? 2.776 -25.607 58.471 1.00 18.88 ? 160 LEU A N 1 ATOM 1214 C CA . LEU A 1 160 ? 4.017 -26.249 58.087 1.00 19.37 ? 160 LEU A CA 1 ATOM 1215 C C . LEU A 1 160 ? 4.937 -25.162 57.551 1.00 19.46 ? 160 LEU A C 1 ATOM 1216 O O . LEU A 1 160 ? 4.492 -24.257 56.838 1.00 19.50 ? 160 LEU A O 1 ATOM 1217 C CB . LEU A 1 160 ? 3.752 -27.391 57.083 1.00 19.29 ? 160 LEU A CB 1 ATOM 1218 C CG . LEU A 1 160 ? 2.707 -28.396 57.618 1.00 19.99 ? 160 LEU A CG 1 ATOM 1219 C CD1 . LEU A 1 160 ? 2.186 -29.341 56.578 1.00 20.47 ? 160 LEU A CD1 1 ATOM 1220 C CD2 . LEU A 1 160 ? 3.239 -29.183 58.819 1.00 22.64 ? 160 LEU A CD2 1 ATOM 1221 N N . PHE A 1 161 ? 6.201 -25.196 57.949 1.00 19.06 ? 161 PHE A N 1 ATOM 1222 C CA . PHE A 1 161 ? 7.122 -24.142 57.561 1.00 19.31 ? 161 PHE A CA 1 ATOM 1223 C C . PHE A 1 161 ? 8.552 -24.683 57.480 1.00 20.39 ? 161 PHE A C 1 ATOM 1224 O O . PHE A 1 161 ? 9.359 -24.494 58.399 1.00 19.06 ? 161 PHE A O 1 ATOM 1225 C CB . PHE A 1 161 ? 7.029 -22.956 58.524 1.00 19.85 ? 161 PHE A CB 1 ATOM 1226 C CG . PHE A 1 161 ? 7.578 -21.640 57.971 1.00 20.69 ? 161 PHE A CG 1 ATOM 1227 C CD1 . PHE A 1 161 ? 6.919 -20.448 58.224 1.00 23.39 ? 161 PHE A CD1 1 ATOM 1228 C CD2 . PHE A 1 161 ? 8.767 -21.598 57.224 1.00 23.42 ? 161 PHE A CD2 1 ATOM 1229 C CE1 . PHE A 1 161 ? 7.402 -19.239 57.734 1.00 23.76 ? 161 PHE A CE1 1 ATOM 1230 C CE2 . PHE A 1 161 ? 9.283 -20.399 56.740 1.00 21.43 ? 161 PHE A CE2 1 ATOM 1231 C CZ . PHE A 1 161 ? 8.597 -19.204 56.997 1.00 23.62 ? 161 PHE A CZ 1 ATOM 1232 N N . ALA A 1 162 ? 8.851 -25.329 56.359 1.00 20.60 ? 162 ALA A N 1 ATOM 1233 C CA . ALA A 1 162 ? 10.225 -25.684 56.016 1.00 20.67 ? 162 ALA A CA 1 ATOM 1234 C C . ALA A 1 162 ? 10.752 -24.700 54.973 1.00 20.75 ? 162 ALA A C 1 ATOM 1235 O O . ALA A 1 162 ? 9.988 -23.961 54.358 1.00 20.08 ? 162 ALA A O 1 ATOM 1236 C CB . ALA A 1 162 ? 10.269 -27.093 55.515 1.00 20.58 ? 162 ALA A CB 1 ATOM 1237 N N . ASP A 1 163 ? 12.067 -24.665 54.788 1.00 20.49 ? 163 ASP A N 1 ATOM 1238 C CA . ASP A 1 163 ? 12.675 -23.754 53.843 1.00 20.77 ? 163 ASP A CA 1 ATOM 1239 C C . ASP A 1 163 ? 11.992 -23.785 52.454 1.00 20.62 ? 163 ASP A C 1 ATOM 1240 O O . ASP A 1 163 ? 11.889 -22.747 51.794 1.00 21.17 ? 163 ASP A O 1 ATOM 1241 C CB . ASP A 1 163 ? 14.192 -24.039 53.770 1.00 21.92 ? 163 ASP A CB 1 ATOM 1242 C CG . ASP A 1 163 ? 14.928 -23.109 52.839 1.00 24.16 ? 163 ASP A CG 1 ATOM 1243 O OD1 . ASP A 1 163 ? 14.732 -21.869 52.874 1.00 27.87 ? 163 ASP A OD1 1 ATOM 1244 O OD2 . ASP A 1 163 ? 15.751 -23.633 52.072 1.00 31.23 ? 163 ASP A OD2 1 ATOM 1245 N N . GLN A 1 164 ? 11.507 -24.955 52.029 1.00 20.28 ? 164 GLN A N 1 ATOM 1246 C CA . GLN A 1 164 ? 10.932 -25.122 50.683 1.00 19.42 ? 164 GLN A CA 1 ATOM 1247 C C . GLN A 1 164 ? 9.609 -25.852 50.718 1.00 19.37 ? 164 GLN A C 1 ATOM 1248 O O . GLN A 1 164 ? 9.236 -26.542 49.756 1.00 18.35 ? 164 GLN A O 1 ATOM 1249 C CB . GLN A 1 164 ? 11.915 -25.866 49.746 1.00 19.75 ? 164 GLN A CB 1 ATOM 1250 C CG . GLN A 1 164 ? 13.187 -25.092 49.450 1.00 18.55 ? 164 GLN A CG 1 ATOM 1251 C CD . GLN A 1 164 ? 14.084 -25.816 48.476 1.00 18.96 ? 164 GLN A CD 1 ATOM 1252 O OE1 . GLN A 1 164 ? 13.912 -25.723 47.270 1.00 22.23 ? 164 GLN A OE1 1 ATOM 1253 N NE2 . GLN A 1 164 ? 15.027 -26.547 48.994 1.00 18.18 ? 164 GLN A NE2 1 ATOM 1254 N N . PHE A 1 165 ? 8.900 -25.705 51.836 1.00 19.46 ? 165 PHE A N 1 ATOM 1255 C CA . PHE A 1 165 ? 7.547 -26.211 51.960 1.00 20.18 ? 165 PHE A CA 1 ATOM 1256 C C . PHE A 1 165 ? 6.804 -25.454 53.060 1.00 20.09 ? 165 PHE A C 1 ATOM 1257 O O . PHE A 1 165 ? 7.101 -25.622 54.255 1.00 19.77 ? 165 PHE A O 1 ATOM 1258 C CB . PHE A 1 165 ? 7.504 -27.696 52.258 1.00 20.23 ? 165 PHE A CB 1 ATOM 1259 C CG . PHE A 1 165 ? 6.129 -28.289 52.140 1.00 22.53 ? 165 PHE A CG 1 ATOM 1260 C CD1 . PHE A 1 165 ? 5.654 -28.736 50.914 1.00 23.60 ? 165 PHE A CD1 1 ATOM 1261 C CD2 . PHE A 1 165 ? 5.304 -28.391 53.243 1.00 23.99 ? 165 PHE A CD2 1 ATOM 1262 C CE1 . PHE A 1 165 ? 4.396 -29.279 50.806 1.00 24.78 ? 165 PHE A CE1 1 ATOM 1263 C CE2 . PHE A 1 165 ? 4.034 -28.944 53.137 1.00 23.45 ? 165 PHE A CE2 1 ATOM 1264 C CZ . PHE A 1 165 ? 3.589 -29.395 51.921 1.00 24.59 ? 165 PHE A CZ 1 ATOM 1265 N N . LEU A 1 166 ? 5.863 -24.613 52.641 1.00 18.30 ? 166 LEU A N 1 ATOM 1266 C CA . LEU A 1 166 ? 5.080 -23.809 53.582 1.00 18.41 ? 166 LEU A CA 1 ATOM 1267 C C . LEU A 1 166 ? 3.633 -24.111 53.311 1.00 17.77 ? 166 LEU A C 1 ATOM 1268 O O . LEU A 1 166 ? 3.226 -24.152 52.168 1.00 17.75 ? 166 LEU A O 1 ATOM 1269 C CB . LEU A 1 166 ? 5.339 -22.318 53.397 1.00 17.16 ? 166 LEU A CB 1 ATOM 1270 C CG . LEU A 1 166 ? 6.706 -21.709 53.760 1.00 19.69 ? 166 LEU A CG 1 ATOM 1271 C CD1 . LEU A 1 166 ? 7.739 -22.034 52.713 1.00 17.69 ? 166 LEU A CD1 1 ATOM 1272 C CD2 . LEU A 1 166 ? 6.539 -20.211 53.845 1.00 20.19 ? 166 LEU A CD2 1 ATOM 1273 N N . GLN A 1 167 ? 2.862 -24.335 54.361 1.00 17.58 ? 167 GLN A N 1 ATOM 1274 C CA . GLN A 1 167 ? 1.457 -24.658 54.175 1.00 16.70 ? 167 GLN A CA 1 ATOM 1275 C C . GLN A 1 167 ? 0.612 -24.085 55.327 1.00 16.56 ? 167 GLN A C 1 ATOM 1276 O O . GLN A 1 167 ? 0.956 -24.224 56.502 1.00 15.08 ? 167 GLN A O 1 ATOM 1277 C CB . GLN A 1 167 ? 1.252 -26.178 54.076 1.00 17.12 ? 167 GLN A CB 1 ATOM 1278 C CG . GLN A 1 167 ? -0.220 -26.578 53.937 1.00 15.78 ? 167 GLN A CG 1 ATOM 1279 C CD . GLN A 1 167 ? -0.450 -28.076 53.767 1.00 17.26 ? 167 GLN A CD 1 ATOM 1280 O OE1 . GLN A 1 167 ? -1.236 -28.693 54.511 1.00 20.07 ? 167 GLN A OE1 1 ATOM 1281 N NE2 . GLN A 1 167 ? 0.197 -28.657 52.801 1.00 14.87 ? 167 GLN A NE2 1 ATOM 1282 N N . LEU A 1 168 ? -0.486 -23.429 54.968 1.00 15.48 ? 168 LEU A N 1 ATOM 1283 C CA . LEU A 1 168 ? -1.477 -23.056 55.935 1.00 15.38 ? 168 LEU A CA 1 ATOM 1284 C C . LEU A 1 168 ? -2.836 -23.290 55.304 1.00 15.37 ? 168 LEU A C 1 ATOM 1285 O O . LEU A 1 168 ? -3.020 -23.023 54.123 1.00 16.05 ? 168 LEU A O 1 ATOM 1286 C CB . LEU A 1 168 ? -1.334 -21.582 56.349 1.00 15.15 ? 168 LEU A CB 1 ATOM 1287 C CG . LEU A 1 168 ? -2.124 -21.180 57.615 1.00 15.40 ? 168 LEU A CG 1 ATOM 1288 C CD1 . LEU A 1 168 ? -1.642 -21.893 58.881 1.00 13.78 ? 168 LEU A CD1 1 ATOM 1289 C CD2 . LEU A 1 168 ? -2.102 -19.720 57.822 1.00 15.01 ? 168 LEU A CD2 1 ATOM 1290 N N . SER A 1 169 ? -3.781 -23.773 56.099 1.00 15.33 ? 169 SER A N 1 ATOM 1291 C CA . SER A 1 169 ? -5.150 -23.998 55.631 1.00 15.19 ? 169 SER A CA 1 ATOM 1292 C C . SER A 1 169 ? -6.076 -23.001 56.285 1.00 15.53 ? 169 SER A C 1 ATOM 1293 O O . SER A 1 169 ? -5.687 -22.352 57.227 1.00 16.23 ? 169 SER A O 1 ATOM 1294 C CB . SER A 1 169 ? -5.610 -25.412 55.960 1.00 14.56 ? 169 SER A CB 1 ATOM 1295 O OG . SER A 1 169 ? -4.583 -26.351 55.712 1.00 16.91 ? 169 SER A OG 1 ATOM 1296 N N . THR A 1 170 ? -7.289 -22.844 55.744 1.00 16.65 ? 170 THR A N 1 ATOM 1297 C CA . THR A 1 170 ? -8.352 -22.091 56.413 1.00 17.14 ? 170 THR A CA 1 ATOM 1298 C C . THR A 1 170 ? -9.677 -22.757 56.103 1.00 16.98 ? 170 THR A C 1 ATOM 1299 O O . THR A 1 170 ? -9.928 -23.137 54.964 1.00 17.05 ? 170 THR A O 1 ATOM 1300 C CB . THR A 1 170 ? -8.425 -20.575 56.015 1.00 17.05 ? 170 THR A CB 1 ATOM 1301 O OG1 . THR A 1 170 ? -9.532 -19.952 56.684 1.00 19.45 ? 170 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 170 ? -8.601 -20.357 54.501 1.00 18.83 ? 170 THR A CG2 1 ATOM 1303 N N . ARG A 1 171 ? -10.502 -22.937 57.123 1.00 16.84 ? 171 ARG A N 1 ATOM 1304 C CA . ARG A 1 171 ? -11.931 -23.124 56.874 1.00 17.49 ? 171 ARG A CA 1 ATOM 1305 C C . ARG A 1 171 ? -12.501 -21.903 56.160 1.00 17.59 ? 171 ARG A C 1 ATOM 1306 O O . ARG A 1 171 ? -11.918 -20.795 56.218 1.00 18.62 ? 171 ARG A O 1 ATOM 1307 C CB . ARG A 1 171 ? -12.677 -23.338 58.168 1.00 17.81 ? 171 ARG A CB 1 ATOM 1308 C CG . ARG A 1 171 ? -12.135 -24.457 59.026 1.00 19.17 ? 171 ARG A CG 1 ATOM 1309 C CD . ARG A 1 171 ? -13.023 -24.703 60.243 1.00 23.73 ? 171 ARG A CD 1 ATOM 1310 N NE . ARG A 1 171 ? -12.183 -24.960 61.411 1.00 25.67 ? 171 ARG A NE 1 ATOM 1311 C CZ . ARG A 1 171 ? -11.903 -26.158 61.882 1.00 25.58 ? 171 ARG A CZ 1 ATOM 1312 N NH1 . ARG A 1 171 ? -12.448 -27.228 61.325 1.00 29.97 ? 171 ARG A NH1 1 ATOM 1313 N NH2 . ARG A 1 171 ? -11.114 -26.275 62.941 1.00 28.08 ? 171 ARG A NH2 1 ATOM 1314 N N . LEU A 1 172 ? -13.642 -22.120 55.512 1.00 17.61 ? 172 LEU A N 1 ATOM 1315 C CA . LEU A 1 172 ? -14.360 -21.130 54.721 1.00 18.40 ? 172 LEU A CA 1 ATOM 1316 C C . LEU A 1 172 ? -15.806 -21.166 55.185 1.00 18.20 ? 172 LEU A C 1 ATOM 1317 O O . LEU A 1 172 ? -16.301 -22.246 55.516 1.00 17.70 ? 172 LEU A O 1 ATOM 1318 C CB . LEU A 1 172 ? -14.263 -21.454 53.205 1.00 18.08 ? 172 LEU A CB 1 ATOM 1319 C CG . LEU A 1 172 ? -12.896 -21.177 52.566 1.00 19.69 ? 172 LEU A CG 1 ATOM 1320 C CD1 . LEU A 1 172 ? -12.774 -21.603 51.087 1.00 17.87 ? 172 LEU A CD1 1 ATOM 1321 C CD2 . LEU A 1 172 ? -12.561 -19.697 52.723 1.00 18.03 ? 172 LEU A CD2 1 ATOM 1322 N N . PRO A 1 173 ? -16.471 -19.988 55.271 1.00 18.71 ? 173 PRO A N 1 ATOM 1323 C CA . PRO A 1 173 ? -17.882 -19.908 55.716 1.00 18.91 ? 173 PRO A CA 1 ATOM 1324 C C . PRO A 1 173 ? -18.940 -20.353 54.724 1.00 20.35 ? 173 PRO A C 1 ATOM 1325 O O . PRO A 1 173 ? -20.131 -20.449 55.092 1.00 21.26 ? 173 PRO A O 1 ATOM 1326 C CB . PRO A 1 173 ? -18.058 -18.409 56.038 1.00 18.00 ? 173 PRO A CB 1 ATOM 1327 C CG . PRO A 1 173 ? -17.188 -17.735 55.155 1.00 17.28 ? 173 PRO A CG 1 ATOM 1328 C CD . PRO A 1 173 ? -15.920 -18.636 55.070 1.00 18.97 ? 173 PRO A CD 1 ATOM 1329 N N . SER A 1 174 ? -18.530 -20.608 53.478 1.00 20.70 ? 174 SER A N 1 ATOM 1330 C CA . SER A 1 174 ? -19.427 -21.001 52.410 1.00 20.44 ? 174 SER A CA 1 ATOM 1331 C C . SER A 1 174 ? -18.676 -21.666 51.264 1.00 20.44 ? 174 SER A C 1 ATOM 1332 O O . SER A 1 174 ? -17.439 -21.653 51.203 1.00 20.28 ? 174 SER A O 1 ATOM 1333 C CB . SER A 1 174 ? -20.202 -19.792 51.869 1.00 20.71 ? 174 SER A CB 1 ATOM 1334 O OG . SER A 1 174 ? -19.351 -18.969 51.077 1.00 22.12 ? 174 SER A OG 1 ATOM 1335 N N . THR A 1 175 ? -19.440 -22.233 50.343 1.00 19.56 ? 175 THR A N 1 ATOM 1336 C CA . THR A 1 175 ? -18.873 -22.758 49.117 1.00 19.86 ? 175 THR A CA 1 ATOM 1337 C C . THR A 1 175 ? -18.958 -21.739 47.988 1.00 19.01 ? 175 THR A C 1 ATOM 1338 O O . THR A 1 175 ? -18.711 -22.088 46.852 1.00 20.16 ? 175 THR A O 1 ATOM 1339 C CB . THR A 1 175 ? -19.549 -24.072 48.688 1.00 20.01 ? 175 THR A CB 1 ATOM 1340 O OG1 . THR A 1 175 ? -20.961 -23.850 48.566 1.00 19.94 ? 175 THR A OG1 1 ATOM 1341 C CG2 . THR A 1 175 ? -19.254 -25.205 49.714 1.00 20.09 ? 175 THR A CG2 1 ATOM 1342 N N . ASN A 1 176 ? -19.316 -20.485 48.291 1.00 18.02 ? 176 ASN A N 1 ATOM 1343 C CA . ASN A 1 176 ? -19.395 -19.447 47.273 1.00 17.41 ? 176 ASN A CA 1 ATOM 1344 C C . ASN A 1 176 ? -18.030 -18.796 47.112 1.00 16.11 ? 176 ASN A C 1 ATOM 1345 O O . ASN A 1 176 ? -17.799 -17.715 47.582 1.00 16.88 ? 176 ASN A O 1 ATOM 1346 C CB . ASN A 1 176 ? -20.478 -18.393 47.594 1.00 17.30 ? 176 ASN A CB 1 ATOM 1347 C CG . ASN A 1 176 ? -21.839 -19.012 47.857 1.00 19.44 ? 176 ASN A CG 1 ATOM 1348 O OD1 . ASN A 1 176 ? -22.230 -19.933 47.179 1.00 19.64 ? 176 ASN A OD1 1 ATOM 1349 N ND2 . ASN A 1 176 ? -22.554 -18.510 48.872 1.00 23.05 ? 176 ASN A ND2 1 ATOM 1350 N N . VAL A 1 177 ? -17.128 -19.491 46.448 1.00 16.45 ? 177 VAL A N 1 ATOM 1351 C CA . VAL A 1 177 ? -15.707 -19.103 46.366 1.00 14.70 ? 177 VAL A CA 1 ATOM 1352 C C . VAL A 1 177 ? -15.376 -18.791 44.904 1.00 13.83 ? 177 VAL A C 1 ATOM 1353 O O . VAL A 1 177 ? -15.637 -19.599 44.040 1.00 14.24 ? 177 VAL A O 1 ATOM 1354 C CB . VAL A 1 177 ? -14.809 -20.243 46.906 1.00 15.16 ? 177 VAL A CB 1 ATOM 1355 C CG1 . VAL A 1 177 ? -13.289 -19.971 46.616 1.00 13.87 ? 177 VAL A CG1 1 ATOM 1356 C CG2 . VAL A 1 177 ? -15.043 -20.450 48.406 1.00 16.54 ? 177 VAL A CG2 1 ATOM 1357 N N . TYR A 1 178 ? -14.780 -17.630 44.640 1.00 13.79 ? 178 TYR A N 1 ATOM 1358 C CA . TYR A 1 178 ? -14.490 -17.169 43.273 1.00 13.49 ? 178 TYR A CA 1 ATOM 1359 C C . TYR A 1 178 ? -13.069 -16.646 43.236 1.00 13.72 ? 178 TYR A C 1 ATOM 1360 O O . TYR A 1 178 ? -12.634 -15.996 44.167 1.00 14.43 ? 178 TYR A O 1 ATOM 1361 C CB . TYR A 1 178 ? -15.442 -16.029 42.894 1.00 12.64 ? 178 TYR A CB 1 ATOM 1362 C CG . TYR A 1 178 ? -16.876 -16.359 43.247 1.00 13.37 ? 178 TYR A CG 1 ATOM 1363 C CD1 . TYR A 1 178 ? -17.687 -17.030 42.347 1.00 12.69 ? 178 TYR A CD1 1 ATOM 1364 C CD2 . TYR A 1 178 ? -17.416 -16.000 44.478 1.00 12.84 ? 178 TYR A CD2 1 ATOM 1365 C CE1 . TYR A 1 178 ? -19.004 -17.352 42.665 1.00 13.47 ? 178 TYR A CE1 1 ATOM 1366 C CE2 . TYR A 1 178 ? -18.749 -16.316 44.798 1.00 12.76 ? 178 TYR A CE2 1 ATOM 1367 C CZ . TYR A 1 178 ? -19.508 -17.016 43.885 1.00 11.82 ? 178 TYR A CZ 1 ATOM 1368 O OH . TYR A 1 178 ? -20.811 -17.346 44.154 1.00 17.62 ? 178 TYR A OH 1 ATOM 1369 N N . GLY A 1 179 ? -12.321 -16.928 42.173 1.00 14.09 ? 179 GLY A N 1 ATOM 1370 C CA . GLY A 1 179 ? -10.937 -16.457 42.165 1.00 13.90 ? 179 GLY A CA 1 ATOM 1371 C C . GLY A 1 179 ? -9.900 -17.505 41.869 1.00 13.85 ? 179 GLY A C 1 ATOM 1372 O O . GLY A 1 179 ? -10.215 -18.554 41.293 1.00 14.29 ? 179 GLY A O 1 ATOM 1373 N N . LEU A 1 180 ? -8.662 -17.174 42.221 1.00 14.08 ? 180 LEU A N 1 ATOM 1374 C CA . LEU A 1 180 ? -7.447 -17.938 41.867 1.00 14.89 ? 180 LEU A CA 1 ATOM 1375 C C . LEU A 1 180 ? -7.169 -17.950 40.380 1.00 14.41 ? 180 LEU A C 1 ATOM 1376 O O . LEU A 1 180 ? -8.083 -17.926 39.565 1.00 14.34 ? 180 LEU A O 1 ATOM 1377 C CB . LEU A 1 180 ? -7.480 -19.376 42.394 1.00 14.99 ? 180 LEU A CB 1 ATOM 1378 C CG . LEU A 1 180 ? -7.924 -19.558 43.845 1.00 17.61 ? 180 LEU A CG 1 ATOM 1379 C CD1 . LEU A 1 180 ? -8.480 -20.994 44.028 1.00 16.35 ? 180 LEU A CD1 1 ATOM 1380 C CD2 . LEU A 1 180 ? -6.821 -19.158 44.870 1.00 17.63 ? 180 LEU A CD2 1 ATOM 1381 N N . GLY A 1 181 ? -5.891 -17.965 40.021 1.00 13.76 ? 181 GLY A N 1 ATOM 1382 C CA . GLY A 1 181 ? -5.505 -18.026 38.635 1.00 13.65 ? 181 GLY A CA 1 ATOM 1383 C C . GLY A 1 181 ? -3.996 -18.124 38.473 1.00 14.32 ? 181 GLY A C 1 ATOM 1384 O O . GLY A 1 181 ? -3.277 -18.108 39.460 1.00 14.69 ? 181 GLY A O 1 ATOM 1385 N N . GLU A 1 182 ? -3.525 -18.206 37.236 1.00 15.12 ? 182 GLU A N 1 ATOM 1386 C CA . GLU A 1 182 ? -4.406 -18.219 36.049 1.00 15.31 ? 182 GLU A CA 1 ATOM 1387 C C . GLU A 1 182 ? -4.740 -19.624 35.600 1.00 15.91 ? 182 GLU A C 1 ATOM 1388 O O . GLU A 1 182 ? -3.841 -20.485 35.457 1.00 15.74 ? 182 GLU A O 1 ATOM 1389 C CB . GLU A 1 182 ? -3.747 -17.450 34.918 1.00 16.50 ? 182 GLU A CB 1 ATOM 1390 C CG . GLU A 1 182 ? -4.632 -17.232 33.713 1.00 14.64 ? 182 GLU A CG 1 ATOM 1391 C CD . GLU A 1 182 ? -3.977 -16.314 32.724 1.00 20.09 ? 182 GLU A CD 1 ATOM 1392 O OE1 . GLU A 1 182 ? -2.766 -15.969 32.921 1.00 17.58 ? 182 GLU A OE1 1 ATOM 1393 O OE2 . GLU A 1 182 ? -4.668 -15.931 31.761 1.00 19.51 ? 182 GLU A OE2 1 ATOM 1394 N N . HIS A 1 183 ? -6.039 -19.885 35.437 1.00 14.92 ? 183 HIS A N 1 ATOM 1395 C CA . HIS A 1 183 ? -6.496 -21.192 35.000 1.00 15.34 ? 183 HIS A CA 1 ATOM 1396 C C . HIS A 1 183 ? -7.753 -21.058 34.122 1.00 15.39 ? 183 HIS A C 1 ATOM 1397 O O . HIS A 1 183 ? -8.403 -20.003 34.112 1.00 15.39 ? 183 HIS A O 1 ATOM 1398 C CB . HIS A 1 183 ? -6.873 -22.133 36.172 1.00 14.40 ? 183 HIS A CB 1 ATOM 1399 C CG . HIS A 1 183 ? -6.058 -21.985 37.417 1.00 14.35 ? 183 HIS A CG 1 ATOM 1400 N ND1 . HIS A 1 183 ? -4.782 -22.517 37.552 1.00 13.88 ? 183 HIS A ND1 1 ATOM 1401 C CD2 . HIS A 1 183 ? -6.390 -21.495 38.634 1.00 8.42 ? 183 HIS A CD2 1 ATOM 1402 C CE1 . HIS A 1 183 ? -4.325 -22.250 38.760 1.00 8.72 ? 183 HIS A CE1 1 ATOM 1403 N NE2 . HIS A 1 183 ? -5.281 -21.640 39.440 1.00 15.20 ? 183 HIS A NE2 1 ATOM 1404 N N . VAL A 1 184 ? -8.088 -22.142 33.423 1.00 14.91 ? 184 VAL A N 1 ATOM 1405 C CA . VAL A 1 184 ? -9.434 -22.334 32.865 1.00 15.61 ? 184 VAL A CA 1 ATOM 1406 C C . VAL A 1 184 ? -10.218 -23.180 33.873 1.00 15.94 ? 184 VAL A C 1 ATOM 1407 O O . VAL A 1 184 ? -10.099 -24.403 33.923 1.00 15.61 ? 184 VAL A O 1 ATOM 1408 C CB . VAL A 1 184 ? -9.378 -23.011 31.483 1.00 15.33 ? 184 VAL A CB 1 ATOM 1409 C CG1 . VAL A 1 184 ? -10.770 -23.367 30.967 1.00 16.31 ? 184 VAL A CG1 1 ATOM 1410 C CG2 . VAL A 1 184 ? -8.601 -22.154 30.478 1.00 13.74 ? 184 VAL A CG2 1 ATOM 1411 N N . HIS A 1 185 ? -10.995 -22.520 34.722 1.00 17.78 ? 185 HIS A N 1 ATOM 1412 C CA . HIS A 1 185 ? -11.759 -23.226 35.738 1.00 17.51 ? 185 HIS A CA 1 ATOM 1413 C C . HIS A 1 185 ? -13.048 -23.824 35.151 1.00 18.90 ? 185 HIS A C 1 ATOM 1414 O O . HIS A 1 185 ? -13.660 -24.672 35.791 1.00 19.10 ? 185 HIS A O 1 ATOM 1415 C CB . HIS A 1 185 ? -12.127 -22.292 36.917 1.00 17.86 ? 185 HIS A CB 1 ATOM 1416 C CG . HIS A 1 185 ? -10.944 -21.723 37.637 1.00 15.90 ? 185 HIS A CG 1 ATOM 1417 N ND1 . HIS A 1 185 ? -10.901 -20.418 38.075 1.00 13.45 ? 185 HIS A ND1 1 ATOM 1418 C CD2 . HIS A 1 185 ? -9.756 -22.280 37.991 1.00 16.35 ? 185 HIS A CD2 1 ATOM 1419 C CE1 . HIS A 1 185 ? -9.735 -20.196 38.662 1.00 19.22 ? 185 HIS A CE1 1 ATOM 1420 N NE2 . HIS A 1 185 ? -9.021 -21.306 38.618 1.00 13.86 ? 185 HIS A NE2 1 ATOM 1421 N N . GLN A 1 186 ? -13.463 -23.346 33.975 1.00 19.49 ? 186 GLN A N 1 ATOM 1422 C CA . GLN A 1 186 ? -14.669 -23.823 33.247 1.00 20.77 ? 186 GLN A CA 1 ATOM 1423 C C . GLN A 1 186 ? -15.980 -23.326 33.858 1.00 20.84 ? 186 GLN A C 1 ATOM 1424 O O . GLN A 1 186 ? -16.852 -22.847 33.142 1.00 21.91 ? 186 GLN A O 1 ATOM 1425 C CB . GLN A 1 186 ? -14.677 -25.346 33.063 1.00 20.24 ? 186 GLN A CB 1 ATOM 1426 C CG . GLN A 1 186 ? -13.385 -25.873 32.390 1.00 21.95 ? 186 GLN A CG 1 ATOM 1427 C CD . GLN A 1 186 ? -13.448 -27.349 32.076 1.00 22.67 ? 186 GLN A CD 1 ATOM 1428 O OE1 . GLN A 1 186 ? -14.531 -27.910 31.891 1.00 24.91 ? 186 GLN A OE1 1 ATOM 1429 N NE2 . GLN A 1 186 ? -12.284 -27.986 32.002 1.00 24.08 ? 186 GLN A NE2 1 ATOM 1430 N N . GLN A 1 187 ? -16.108 -23.427 35.170 1.00 20.22 ? 187 GLN A N 1 ATOM 1431 C CA . GLN A 1 187 ? -17.169 -22.725 35.893 1.00 20.85 ? 187 GLN A CA 1 ATOM 1432 C C . GLN A 1 187 ? -16.597 -21.531 36.662 1.00 18.99 ? 187 GLN A C 1 ATOM 1433 O O . GLN A 1 187 ? -15.399 -21.419 36.803 1.00 18.01 ? 187 GLN A O 1 ATOM 1434 C CB . GLN A 1 187 ? -17.872 -23.688 36.826 1.00 22.01 ? 187 GLN A CB 1 ATOM 1435 C CG . GLN A 1 187 ? -18.768 -24.677 36.100 1.00 27.39 ? 187 GLN A CG 1 ATOM 1436 C CD . GLN A 1 187 ? -19.331 -25.710 37.042 1.00 36.97 ? 187 GLN A CD 1 ATOM 1437 O OE1 . GLN A 1 187 ? -18.614 -26.222 37.923 1.00 41.67 ? 187 GLN A OE1 1 ATOM 1438 N NE2 . GLN A 1 187 ? -20.629 -26.038 36.871 1.00 40.37 ? 187 GLN A NE2 1 ATOM 1439 N N . TYR A 1 188 ? -17.447 -20.630 37.144 1.00 17.91 ? 188 TYR A N 1 ATOM 1440 C CA . TYR A 1 188 ? -16.949 -19.472 37.882 1.00 16.95 ? 188 TYR A CA 1 ATOM 1441 C C . TYR A 1 188 ? -16.952 -19.742 39.408 1.00 17.25 ? 188 TYR A C 1 ATOM 1442 O O . TYR A 1 188 ? -15.963 -19.469 40.099 1.00 16.09 ? 188 TYR A O 1 ATOM 1443 C CB . TYR A 1 188 ? -17.729 -18.197 37.491 1.00 16.61 ? 188 TYR A CB 1 ATOM 1444 C CG . TYR A 1 188 ? -17.313 -16.939 38.211 1.00 14.21 ? 188 TYR A CG 1 ATOM 1445 C CD1 . TYR A 1 188 ? -16.016 -16.432 38.083 1.00 14.20 ? 188 TYR A CD1 1 ATOM 1446 C CD2 . TYR A 1 188 ? -18.210 -16.251 39.014 1.00 14.12 ? 188 TYR A CD2 1 ATOM 1447 C CE1 . TYR A 1 188 ? -15.622 -15.298 38.734 1.00 12.65 ? 188 TYR A CE1 1 ATOM 1448 C CE2 . TYR A 1 188 ? -17.811 -15.104 39.679 1.00 14.08 ? 188 TYR A CE2 1 ATOM 1449 C CZ . TYR A 1 188 ? -16.525 -14.634 39.528 1.00 13.87 ? 188 TYR A CZ 1 ATOM 1450 O OH . TYR A 1 188 ? -16.126 -13.490 40.184 1.00 15.37 ? 188 TYR A OH 1 ATOM 1451 N N . ARG A 1 189 ? -18.053 -20.288 39.931 1.00 17.12 ? 189 ARG A N 1 ATOM 1452 C CA . ARG A 1 189 ? -18.059 -20.703 41.318 1.00 17.61 ? 189 ARG A CA 1 ATOM 1453 C C . ARG A 1 189 ? -17.219 -21.953 41.494 1.00 18.83 ? 189 ARG A C 1 ATOM 1454 O O . ARG A 1 189 ? -17.398 -22.962 40.814 1.00 17.97 ? 189 ARG A O 1 ATOM 1455 C CB . ARG A 1 189 ? -19.455 -20.873 41.914 1.00 18.31 ? 189 ARG A CB 1 ATOM 1456 C CG . ARG A 1 189 ? -19.398 -21.087 43.429 1.00 16.80 ? 189 ARG A CG 1 ATOM 1457 C CD . ARG A 1 189 ? -20.768 -21.159 44.059 1.00 22.84 ? 189 ARG A CD 1 ATOM 1458 N NE . ARG A 1 189 ? -21.552 -22.274 43.550 1.00 23.65 ? 189 ARG A NE 1 ATOM 1459 C CZ . ARG A 1 189 ? -21.611 -23.486 44.099 1.00 28.01 ? 189 ARG A CZ 1 ATOM 1460 N NH1 . ARG A 1 189 ? -20.944 -23.765 45.210 1.00 28.26 ? 189 ARG A NH1 1 ATOM 1461 N NH2 . ARG A 1 189 ? -22.364 -24.429 43.538 1.00 30.29 ? 189 ARG A NH2 1 ATOM 1462 N N . HIS A 1 190 ? -16.242 -21.865 42.382 1.00 20.84 ? 190 HIS A N 1 ATOM 1463 C CA . HIS A 1 190 ? -15.361 -23.004 42.580 1.00 23.00 ? 190 HIS A CA 1 ATOM 1464 C C . HIS A 1 190 ? -16.053 -24.198 43.135 1.00 25.21 ? 190 HIS A C 1 ATOM 1465 O O . HIS A 1 190 ? -16.675 -24.121 44.188 1.00 25.35 ? 190 HIS A O 1 ATOM 1466 C CB . HIS A 1 190 ? -14.214 -22.653 43.494 1.00 23.07 ? 190 HIS A CB 1 ATOM 1467 C CG . HIS A 1 190 ? -13.032 -22.172 42.746 1.00 22.20 ? 190 HIS A CG 1 ATOM 1468 N ND1 . HIS A 1 190 ? -12.761 -20.836 42.576 1.00 25.13 ? 190 HIS A ND1 1 ATOM 1469 C CD2 . HIS A 1 190 ? -12.100 -22.843 42.041 1.00 23.46 ? 190 HIS A CD2 1 ATOM 1470 C CE1 . HIS A 1 190 ? -11.662 -20.702 41.859 1.00 23.91 ? 190 HIS A CE1 1 ATOM 1471 N NE2 . HIS A 1 190 ? -11.239 -21.907 41.525 1.00 26.13 ? 190 HIS A NE2 1 ATOM 1472 N N . ASP A 1 191 ? -15.978 -25.263 42.333 1.00 28.41 ? 191 ASP A N 1 ATOM 1473 C CA . ASP A 1 191 ? -15.986 -26.644 42.762 1.00 30.20 ? 191 ASP A CA 1 ATOM 1474 C C . ASP A 1 191 ? -15.077 -26.830 43.995 1.00 29.95 ? 191 ASP A C 1 ATOM 1475 O O . ASP A 1 191 ? -13.841 -27.052 43.852 1.00 29.32 ? 191 ASP A O 1 ATOM 1476 C CB . ASP A 1 191 ? -15.491 -27.525 41.600 1.00 31.51 ? 191 ASP A CB 1 ATOM 1477 C CG . ASP A 1 191 ? -15.664 -28.992 41.889 1.00 34.22 ? 191 ASP A CG 1 ATOM 1478 O OD1 . ASP A 1 191 ? -16.198 -29.265 42.987 1.00 36.01 ? 191 ASP A OD1 1 ATOM 1479 O OD2 . ASP A 1 191 ? -15.307 -29.854 41.037 1.00 36.90 ? 191 ASP A OD2 1 ATOM 1480 N N . MET A 1 192 ? -15.712 -26.711 45.179 1.00 29.32 ? 192 MET A N 1 ATOM 1481 C CA . MET A 1 192 ? -15.091 -26.942 46.493 1.00 28.72 ? 192 MET A CA 1 ATOM 1482 C C . MET A 1 192 ? -14.954 -28.418 46.782 1.00 29.02 ? 192 MET A C 1 ATOM 1483 O O . MET A 1 192 ? -14.544 -28.809 47.856 1.00 29.52 ? 192 MET A O 1 ATOM 1484 C CB . MET A 1 192 ? -15.871 -26.279 47.639 1.00 28.83 ? 192 MET A CB 1 ATOM 1485 C CG . MET A 1 192 ? -15.801 -24.747 47.695 1.00 26.66 ? 192 MET A CG 1 ATOM 1486 S SD . MET A 1 192 ? -14.122 -24.117 47.498 1.00 22.69 ? 192 MET A SD 1 ATOM 1487 C CE . MET A 1 192 ? -13.410 -24.650 49.059 1.00 20.84 ? 192 MET A CE 1 ATOM 1488 N N . ASN A 1 193 ? -15.273 -29.255 45.813 1.00 29.02 ? 193 ASN A N 1 ATOM 1489 C CA . ASN A 1 193 ? -14.971 -30.634 45.972 1.00 28.92 ? 193 ASN A CA 1 ATOM 1490 C C . ASN A 1 193 ? -13.456 -30.727 45.821 1.00 28.09 ? 193 ASN A C 1 ATOM 1491 O O . ASN A 1 193 ? -12.791 -29.740 45.440 1.00 28.91 ? 193 ASN A O 1 ATOM 1492 C CB . ASN A 1 193 ? -15.787 -31.509 45.007 1.00 30.62 ? 193 ASN A CB 1 ATOM 1493 C CG . ASN A 1 193 ? -17.275 -31.631 45.426 1.00 33.88 ? 193 ASN A CG 1 ATOM 1494 O OD1 . ASN A 1 193 ? -18.087 -32.208 44.690 1.00 41.19 ? 193 ASN A OD1 1 ATOM 1495 N ND2 . ASN A 1 193 ? -17.631 -31.093 46.606 1.00 34.67 ? 193 ASN A ND2 1 ATOM 1496 N N . TRP A 1 194 ? -12.908 -31.867 46.188 1.00 25.07 ? 194 TRP A N 1 ATOM 1497 C CA . TRP A 1 194 ? -11.462 -32.041 46.306 1.00 22.90 ? 194 TRP A CA 1 ATOM 1498 C C . TRP A 1 194 ? -10.786 -31.663 45.000 1.00 22.46 ? 194 TRP A C 1 ATOM 1499 O O . TRP A 1 194 ? -10.933 -32.375 44.012 1.00 23.53 ? 194 TRP A O 1 ATOM 1500 C CB . TRP A 1 194 ? -11.187 -33.504 46.680 1.00 20.59 ? 194 TRP A CB 1 ATOM 1501 C CG . TRP A 1 194 ? -11.955 -33.931 47.925 1.00 18.12 ? 194 TRP A CG 1 ATOM 1502 C CD1 . TRP A 1 194 ? -13.240 -34.433 47.983 1.00 19.02 ? 194 TRP A CD1 1 ATOM 1503 C CD2 . TRP A 1 194 ? -11.486 -33.882 49.270 1.00 17.69 ? 194 TRP A CD2 1 ATOM 1504 N NE1 . TRP A 1 194 ? -13.584 -34.689 49.286 1.00 18.65 ? 194 TRP A NE1 1 ATOM 1505 C CE2 . TRP A 1 194 ? -12.528 -34.367 50.097 1.00 15.93 ? 194 TRP A CE2 1 ATOM 1506 C CE3 . TRP A 1 194 ? -10.271 -33.490 49.862 1.00 12.61 ? 194 TRP A CE3 1 ATOM 1507 C CZ2 . TRP A 1 194 ? -12.399 -34.464 51.476 1.00 15.27 ? 194 TRP A CZ2 1 ATOM 1508 C CZ3 . TRP A 1 194 ? -10.146 -33.586 51.227 1.00 15.92 ? 194 TRP A CZ3 1 ATOM 1509 C CH2 . TRP A 1 194 ? -11.213 -34.055 52.026 1.00 16.79 ? 194 TRP A CH2 1 ATOM 1510 N N . LYS A 1 195 ? -10.100 -30.517 44.986 1.00 21.92 ? 195 LYS A N 1 ATOM 1511 C CA . LYS A 1 195 ? -9.454 -29.963 43.771 1.00 20.97 ? 195 LYS A CA 1 ATOM 1512 C C . LYS A 1 195 ? -8.212 -29.200 44.120 1.00 19.45 ? 195 LYS A C 1 ATOM 1513 O O . LYS A 1 195 ? -8.235 -28.354 45.011 1.00 19.99 ? 195 LYS A O 1 ATOM 1514 C CB . LYS A 1 195 ? -10.382 -29.018 42.978 1.00 21.57 ? 195 LYS A CB 1 ATOM 1515 C CG . LYS A 1 195 ? -10.814 -29.521 41.593 1.00 24.34 ? 195 LYS A CG 1 ATOM 1516 C CD . LYS A 1 195 ? -9.676 -30.091 40.708 1.00 29.34 ? 195 LYS A CD 1 ATOM 1517 C CE . LYS A 1 195 ? -9.070 -29.091 39.736 1.00 28.20 ? 195 LYS A CE 1 ATOM 1518 N NZ . LYS A 1 195 ? -8.584 -29.737 38.461 1.00 29.88 ? 195 LYS A NZ 1 ATOM 1519 N N . THR A 1 196 ? -7.129 -29.506 43.427 1.00 17.41 ? 196 THR A N 1 ATOM 1520 C CA . THR A 1 196 ? -5.880 -28.763 43.550 1.00 15.80 ? 196 THR A CA 1 ATOM 1521 C C . THR A 1 196 ? -5.652 -27.941 42.287 1.00 15.35 ? 196 THR A C 1 ATOM 1522 O O . THR A 1 196 ? -5.716 -28.478 41.155 1.00 15.87 ? 196 THR A O 1 ATOM 1523 C CB . THR A 1 196 ? -4.683 -29.739 43.796 1.00 15.84 ? 196 THR A CB 1 ATOM 1524 O OG1 . THR A 1 196 ? -4.975 -30.570 44.927 1.00 14.61 ? 196 THR A OG1 1 ATOM 1525 C CG2 . THR A 1 196 ? -3.388 -28.980 44.074 1.00 16.37 ? 196 THR A CG2 1 ATOM 1526 N N . TRP A 1 197 ? -5.406 -26.643 42.478 1.00 14.48 ? 197 TRP A N 1 ATOM 1527 C CA . TRP A 1 197 ? -5.047 -25.726 41.404 1.00 13.75 ? 197 TRP A CA 1 ATOM 1528 C C . TRP A 1 197 ? -3.622 -25.288 41.597 1.00 13.62 ? 197 TRP A C 1 ATOM 1529 O O . TRP A 1 197 ? -3.335 -24.603 42.581 1.00 13.73 ? 197 TRP A O 1 ATOM 1530 C CB . TRP A 1 197 ? -5.962 -24.498 41.418 1.00 13.23 ? 197 TRP A CB 1 ATOM 1531 C CG . TRP A 1 197 ? -7.378 -24.864 41.095 1.00 13.32 ? 197 TRP A CG 1 ATOM 1532 C CD1 . TRP A 1 197 ? -8.400 -25.050 41.985 1.00 15.90 ? 197 TRP A CD1 1 ATOM 1533 C CD2 . TRP A 1 197 ? -7.908 -25.156 39.803 1.00 13.98 ? 197 TRP A CD2 1 ATOM 1534 N NE1 . TRP A 1 197 ? -9.561 -25.421 41.311 1.00 16.48 ? 197 TRP A NE1 1 ATOM 1535 C CE2 . TRP A 1 197 ? -9.281 -25.493 39.974 1.00 15.03 ? 197 TRP A CE2 1 ATOM 1536 C CE3 . TRP A 1 197 ? -7.357 -25.184 38.506 1.00 12.50 ? 197 TRP A CE3 1 ATOM 1537 C CZ2 . TRP A 1 197 ? -10.109 -25.810 38.901 1.00 15.28 ? 197 TRP A CZ2 1 ATOM 1538 C CZ3 . TRP A 1 197 ? -8.182 -25.501 37.438 1.00 14.09 ? 197 TRP A CZ3 1 ATOM 1539 C CH2 . TRP A 1 197 ? -9.553 -25.793 37.643 1.00 14.74 ? 197 TRP A CH2 1 ATOM 1540 N N . PRO A 1 198 ? -2.729 -25.681 40.668 1.00 14.43 ? 198 PRO A N 1 ATOM 1541 C CA . PRO A 1 198 ? -1.353 -25.227 40.700 1.00 14.69 ? 198 PRO A CA 1 ATOM 1542 C C . PRO A 1 198 ? -1.200 -23.828 40.126 1.00 15.35 ? 198 PRO A C 1 ATOM 1543 O O . PRO A 1 198 ? -1.934 -23.437 39.198 1.00 16.32 ? 198 PRO A O 1 ATOM 1544 C CB . PRO A 1 198 ? -0.633 -26.254 39.819 1.00 15.11 ? 198 PRO A CB 1 ATOM 1545 C CG . PRO A 1 198 ? -1.663 -26.640 38.792 1.00 14.90 ? 198 PRO A CG 1 ATOM 1546 C CD . PRO A 1 198 ? -2.974 -26.624 39.548 1.00 13.98 ? 198 PRO A CD 1 ATOM 1547 N N . ILE A 1 199 ? -0.264 -23.074 40.694 1.00 15.07 ? 199 ILE A N 1 ATOM 1548 C CA . ILE A 1 199 ? 0.011 -21.706 40.299 1.00 14.86 ? 199 ILE A CA 1 ATOM 1549 C C . ILE A 1 199 ? 1.538 -21.518 40.075 1.00 15.94 ? 199 ILE A C 1 ATOM 1550 O O . ILE A 1 199 ? 2.320 -21.537 41.002 1.00 15.06 ? 199 ILE A O 1 ATOM 1551 C CB . ILE A 1 199 ? -0.543 -20.689 41.354 1.00 15.24 ? 199 ILE A CB 1 ATOM 1552 C CG1 . ILE A 1 199 ? -2.073 -20.862 41.543 1.00 15.12 ? 199 ILE A CG1 1 ATOM 1553 C CG2 . ILE A 1 199 ? -0.244 -19.244 40.934 1.00 14.64 ? 199 ILE A CG2 1 ATOM 1554 C CD1 . ILE A 1 199 ? -2.673 -19.972 42.638 1.00 14.25 ? 199 ILE A CD1 1 ATOM 1555 N N . PHE A 1 200 ? 1.932 -21.350 38.819 1.00 16.82 ? 200 PHE A N 1 ATOM 1556 C CA . PHE A 1 200 ? 3.320 -21.050 38.453 1.00 17.37 ? 200 PHE A CA 1 ATOM 1557 C C . PHE A 1 200 ? 3.275 -20.633 37.015 1.00 16.36 ? 200 PHE A C 1 ATOM 1558 O O . PHE A 1 200 ? 2.810 -21.398 36.169 1.00 17.40 ? 200 PHE A O 1 ATOM 1559 C CB . PHE A 1 200 ? 4.196 -22.310 38.629 1.00 17.31 ? 200 PHE A CB 1 ATOM 1560 C CG . PHE A 1 200 ? 5.664 -22.068 38.491 1.00 20.05 ? 200 PHE A CG 1 ATOM 1561 C CD1 . PHE A 1 200 ? 6.355 -21.330 39.441 1.00 19.24 ? 200 PHE A CD1 1 ATOM 1562 C CD2 . PHE A 1 200 ? 6.367 -22.629 37.427 1.00 20.26 ? 200 PHE A CD2 1 ATOM 1563 C CE1 . PHE A 1 200 ? 7.728 -21.142 39.334 1.00 20.37 ? 200 PHE A CE1 1 ATOM 1564 C CE2 . PHE A 1 200 ? 7.737 -22.429 37.310 1.00 19.33 ? 200 PHE A CE2 1 ATOM 1565 C CZ . PHE A 1 200 ? 8.408 -21.691 38.259 1.00 18.98 ? 200 PHE A CZ 1 ATOM 1566 N N . ASN A 1 201 ? 3.754 -19.419 36.737 1.00 16.54 ? 201 ASN A N 1 ATOM 1567 C CA . ASN A 1 201 ? 3.647 -18.817 35.421 1.00 16.23 ? 201 ASN A CA 1 ATOM 1568 C C . ASN A 1 201 ? 4.282 -19.696 34.364 1.00 16.80 ? 201 ASN A C 1 ATOM 1569 O O . ASN A 1 201 ? 5.511 -20.006 34.390 1.00 15.93 ? 201 ASN A O 1 ATOM 1570 C CB . ASN A 1 201 ? 4.222 -17.392 35.422 1.00 15.98 ? 201 ASN A CB 1 ATOM 1571 C CG . ASN A 1 201 ? 3.398 -16.447 36.301 1.00 18.11 ? 201 ASN A CG 1 ATOM 1572 O OD1 . ASN A 1 201 ? 2.393 -16.868 36.909 1.00 17.40 ? 201 ASN A OD1 1 ATOM 1573 N ND2 . ASN A 1 201 ? 3.790 -15.183 36.355 1.00 14.37 ? 201 ASN A ND2 1 ATOM 1574 N N . ARG A 1 202 ? 3.443 -20.116 33.443 1.00 15.19 ? 202 ARG A N 1 ATOM 1575 C CA . ARG A 1 202 ? 3.864 -21.116 32.454 1.00 15.55 ? 202 ARG A CA 1 ATOM 1576 C C . ARG A 1 202 ? 3.199 -20.874 31.102 1.00 16.44 ? 202 ARG A C 1 ATOM 1577 O O . ARG A 1 202 ? 1.972 -20.588 31.010 1.00 14.97 ? 202 ARG A O 1 ATOM 1578 C CB . ARG A 1 202 ? 3.547 -22.527 32.994 1.00 15.45 ? 202 ARG A CB 1 ATOM 1579 C CG . ARG A 1 202 ? 3.537 -23.667 32.015 1.00 14.44 ? 202 ARG A CG 1 ATOM 1580 C CD . ARG A 1 202 ? 4.948 -24.050 31.546 1.00 18.26 ? 202 ARG A CD 1 ATOM 1581 N NE . ARG A 1 202 ? 4.907 -24.922 30.363 1.00 18.73 ? 202 ARG A NE 1 ATOM 1582 C CZ . ARG A 1 202 ? 5.000 -26.245 30.422 1.00 19.91 ? 202 ARG A CZ 1 ATOM 1583 N NH1 . ARG A 1 202 ? 5.126 -26.827 31.602 1.00 18.84 ? 202 ARG A NH1 1 ATOM 1584 N NH2 . ARG A 1 202 ? 4.957 -26.981 29.309 1.00 18.80 ? 202 ARG A NH2 1 ATOM 1585 N N . ASP A 1 203 ? 4.018 -21.001 30.057 1.00 17.10 ? 203 ASP A N 1 ATOM 1586 C CA . ASP A 1 203 ? 3.549 -21.077 28.685 1.00 18.18 ? 203 ASP A CA 1 ATOM 1587 C C . ASP A 1 203 ? 2.868 -22.415 28.455 1.00 19.14 ? 203 ASP A C 1 ATOM 1588 O O . ASP A 1 203 ? 3.534 -23.453 28.313 1.00 18.05 ? 203 ASP A O 1 ATOM 1589 C CB . ASP A 1 203 ? 4.733 -20.884 27.732 1.00 18.57 ? 203 ASP A CB 1 ATOM 1590 C CG . ASP A 1 203 ? 4.316 -20.741 26.283 1.00 20.09 ? 203 ASP A CG 1 ATOM 1591 O OD1 . ASP A 1 203 ? 3.200 -21.186 25.915 1.00 24.10 ? 203 ASP A OD1 1 ATOM 1592 O OD2 . ASP A 1 203 ? 5.123 -20.189 25.499 1.00 20.95 ? 203 ASP A OD2 1 ATOM 1593 N N . THR A 1 204 ? 1.529 -22.391 28.469 1.00 19.85 ? 204 THR A N 1 ATOM 1594 C CA . THR A 1 204 ? 0.708 -23.584 28.309 1.00 21.83 ? 204 THR A CA 1 ATOM 1595 C C . THR A 1 204 ? -0.649 -23.213 27.760 1.00 21.37 ? 204 THR A C 1 ATOM 1596 O O . THR A 1 204 ? -1.055 -22.068 27.837 1.00 22.08 ? 204 THR A O 1 ATOM 1597 C CB . THR A 1 204 ? 0.447 -24.362 29.620 1.00 21.83 ? 204 THR A CB 1 ATOM 1598 O OG1 . THR A 1 204 ? -0.516 -23.681 30.426 1.00 28.81 ? 204 THR A OG1 1 ATOM 1599 C CG2 . THR A 1 204 ? 1.675 -24.549 30.411 1.00 25.70 ? 204 THR A CG2 1 ATOM 1600 N N . THR A 1 205 ? -1.355 -24.201 27.232 1.00 21.36 ? 205 THR A N 1 ATOM 1601 C CA . THR A 1 205 ? -2.597 -23.966 26.547 1.00 21.70 ? 205 THR A CA 1 ATOM 1602 C C . THR A 1 205 ? -3.771 -23.852 27.521 1.00 21.27 ? 205 THR A C 1 ATOM 1603 O O . THR A 1 205 ? -4.018 -24.749 28.306 1.00 20.16 ? 205 THR A O 1 ATOM 1604 C CB . THR A 1 205 ? -2.883 -25.081 25.512 1.00 22.13 ? 205 THR A CB 1 ATOM 1605 O OG1 . THR A 1 205 ? -1.726 -25.275 24.684 1.00 24.00 ? 205 THR A OG1 1 ATOM 1606 C CG2 . THR A 1 205 ? -4.105 -24.723 24.639 1.00 18.94 ? 205 THR A CG2 1 ATOM 1607 N N . PRO A 1 206 ? -4.511 -22.745 27.450 1.00 21.91 ? 206 PRO A N 1 ATOM 1608 C CA . PRO A 1 206 ? -5.782 -22.749 28.179 1.00 22.14 ? 206 PRO A CA 1 ATOM 1609 C C . PRO A 1 206 ? -6.734 -23.757 27.579 1.00 22.23 ? 206 PRO A C 1 ATOM 1610 O O . PRO A 1 206 ? -7.403 -23.458 26.614 1.00 24.35 ? 206 PRO A O 1 ATOM 1611 C CB . PRO A 1 206 ? -6.303 -21.308 28.018 1.00 21.97 ? 206 PRO A CB 1 ATOM 1612 C CG . PRO A 1 206 ? -5.585 -20.753 26.819 1.00 22.65 ? 206 PRO A CG 1 ATOM 1613 C CD . PRO A 1 206 ? -4.247 -21.466 26.764 1.00 22.41 ? 206 PRO A CD 1 ATOM 1614 N N . ASN A 1 207 ? -6.788 -24.956 28.143 1.00 22.71 ? 207 ASN A N 1 ATOM 1615 C CA . ASN A 1 207 ? -7.711 -25.988 27.667 1.00 22.46 ? 207 ASN A CA 1 ATOM 1616 C C . ASN A 1 207 ? -8.472 -26.596 28.834 1.00 22.69 ? 207 ASN A C 1 ATOM 1617 O O . ASN A 1 207 ? -8.424 -26.075 29.954 1.00 22.63 ? 207 ASN A O 1 ATOM 1618 C CB . ASN A 1 207 ? -6.965 -27.072 26.881 1.00 22.78 ? 207 ASN A CB 1 ATOM 1619 C CG . ASN A 1 207 ? -5.750 -27.630 27.632 1.00 22.02 ? 207 ASN A CG 1 ATOM 1620 O OD1 . ASN A 1 207 ? -5.683 -27.600 28.858 1.00 22.96 ? 207 ASN A OD1 1 ATOM 1621 N ND2 . ASN A 1 207 ? -4.802 -28.153 26.892 1.00 22.07 ? 207 ASN A ND2 1 ATOM 1622 N N . GLY A 1 208 ? -9.164 -27.696 28.571 1.00 22.66 ? 208 GLY A N 1 ATOM 1623 C CA . GLY A 1 208 ? -9.877 -28.460 29.598 1.00 22.28 ? 208 GLY A CA 1 ATOM 1624 C C . GLY A 1 208 ? -9.057 -29.163 30.671 1.00 22.25 ? 208 GLY A C 1 ATOM 1625 O O . GLY A 1 208 ? -9.631 -29.746 31.578 1.00 22.07 ? 208 GLY A O 1 ATOM 1626 N N . ASN A 1 209 ? -7.723 -29.105 30.600 1.00 22.83 ? 209 ASN A N 1 ATOM 1627 C CA . ASN A 1 209 ? -6.880 -29.825 31.578 1.00 22.77 ? 209 ASN A CA 1 ATOM 1628 C C . ASN A 1 209 ? -6.688 -29.189 32.964 1.00 22.53 ? 209 ASN A C 1 ATOM 1629 O O . ASN A 1 209 ? -6.196 -29.842 33.899 1.00 23.54 ? 209 ASN A O 1 ATOM 1630 C CB . ASN A 1 209 ? -5.527 -30.245 30.963 1.00 23.53 ? 209 ASN A CB 1 ATOM 1631 C CG . ASN A 1 209 ? -5.642 -31.498 30.088 1.00 26.38 ? 209 ASN A CG 1 ATOM 1632 O OD1 . ASN A 1 209 ? -6.019 -32.575 30.574 1.00 28.53 ? 209 ASN A OD1 1 ATOM 1633 N ND2 . ASN A 1 209 ? -5.306 -31.368 28.793 1.00 27.68 ? 209 ASN A ND2 1 ATOM 1634 N N . GLY A 1 210 ? -7.051 -27.922 33.115 1.00 21.59 ? 210 GLY A N 1 ATOM 1635 C CA . GLY A 1 210 ? -6.928 -27.269 34.416 1.00 20.08 ? 210 GLY A CA 1 ATOM 1636 C C . GLY A 1 210 ? -5.495 -27.108 34.928 1.00 19.59 ? 210 GLY A C 1 ATOM 1637 O O . GLY A 1 210 ? -5.248 -27.229 36.134 1.00 19.77 ? 210 GLY A O 1 ATOM 1638 N N . THR A 1 211 ? -4.555 -26.824 34.033 1.00 17.97 ? 211 THR A N 1 ATOM 1639 C CA . THR A 1 211 ? -3.151 -26.640 34.447 1.00 17.37 ? 211 THR A CA 1 ATOM 1640 C C . THR A 1 211 ? -2.896 -25.198 34.899 1.00 16.73 ? 211 THR A C 1 ATOM 1641 O O . THR A 1 211 ? -3.745 -24.301 34.700 1.00 15.21 ? 211 THR A O 1 ATOM 1642 C CB . THR A 1 211 ? -2.162 -26.957 33.303 1.00 16.44 ? 211 THR A CB 1 ATOM 1643 O OG1 . THR A 1 211 ? -2.325 -25.985 32.270 1.00 19.55 ? 211 THR A OG1 1 ATOM 1644 C CG2 . THR A 1 211 ? -2.410 -28.289 32.706 1.00 17.38 ? 211 THR A CG2 1 ATOM 1645 N N . ASN A 1 212 ? -1.708 -24.972 35.473 1.00 15.13 ? 212 ASN A N 1 ATOM 1646 C CA . ASN A 1 212 ? -1.230 -23.636 35.668 1.00 15.18 ? 212 ASN A CA 1 ATOM 1647 C C . ASN A 1 212 ? -1.046 -22.969 34.300 1.00 14.90 ? 212 ASN A C 1 ATOM 1648 O O . ASN A 1 212 ? -0.652 -23.623 33.330 1.00 16.45 ? 212 ASN A O 1 ATOM 1649 C CB . ASN A 1 212 ? 0.078 -23.639 36.457 1.00 14.90 ? 212 ASN A CB 1 ATOM 1650 C CG . ASN A 1 212 ? 1.086 -24.630 35.920 1.00 15.90 ? 212 ASN A CG 1 ATOM 1651 O OD1 . ASN A 1 212 ? 0.792 -25.822 35.799 1.00 13.49 ? 212 ASN A OD1 1 ATOM 1652 N ND2 . ASN A 1 212 ? 2.297 -24.156 35.659 1.00 13.84 ? 212 ASN A ND2 1 ATOM 1653 N N . LEU A 1 213 ? -1.364 -21.682 34.203 1.00 13.48 ? 213 LEU A N 1 ATOM 1654 C CA . LEU A 1 213 ? -1.205 -20.955 32.953 1.00 13.05 ? 213 LEU A CA 1 ATOM 1655 C C . LEU A 1 213 ? -0.214 -19.794 33.105 1.00 14.19 ? 213 LEU A C 1 ATOM 1656 O O . LEU A 1 213 ? 0.737 -19.876 33.895 1.00 14.46 ? 213 LEU A O 1 ATOM 1657 C CB . LEU A 1 213 ? -2.595 -20.578 32.343 1.00 14.10 ? 213 LEU A CB 1 ATOM 1658 C CG . LEU A 1 213 ? -3.569 -21.754 32.116 1.00 9.05 ? 213 LEU A CG 1 ATOM 1659 C CD1 . LEU A 1 213 ? -5.041 -21.259 31.738 1.00 11.85 ? 213 LEU A CD1 1 ATOM 1660 C CD2 . LEU A 1 213 ? -3.113 -22.755 31.096 1.00 9.51 ? 213 LEU A CD2 1 ATOM 1661 N N . TYR A 1 214 ? -0.422 -18.724 32.357 1.00 14.46 ? 214 TYR A N 1 ATOM 1662 C CA . TYR A 1 214 ? 0.539 -17.639 32.206 1.00 14.28 ? 214 TYR A CA 1 ATOM 1663 C C . TYR A 1 214 ? 0.785 -16.717 33.401 1.00 14.29 ? 214 TYR A C 1 ATOM 1664 O O . TYR A 1 214 ? 1.921 -16.177 33.568 1.00 13.56 ? 214 TYR A O 1 ATOM 1665 C CB . TYR A 1 214 ? 0.128 -16.757 31.029 1.00 14.53 ? 214 TYR A CB 1 ATOM 1666 C CG . TYR A 1 214 ? -0.360 -17.503 29.836 1.00 15.31 ? 214 TYR A CG 1 ATOM 1667 C CD1 . TYR A 1 214 ? 0.514 -18.213 29.030 1.00 15.82 ? 214 TYR A CD1 1 ATOM 1668 C CD2 . TYR A 1 214 ? -1.702 -17.474 29.495 1.00 15.18 ? 214 TYR A CD2 1 ATOM 1669 C CE1 . TYR A 1 214 ? 0.062 -18.889 27.914 1.00 16.61 ? 214 TYR A CE1 1 ATOM 1670 C CE2 . TYR A 1 214 ? -2.163 -18.133 28.399 1.00 16.22 ? 214 TYR A CE2 1 ATOM 1671 C CZ . TYR A 1 214 ? -1.291 -18.840 27.616 1.00 16.49 ? 214 TYR A CZ 1 ATOM 1672 O OH . TYR A 1 214 ? -1.777 -19.478 26.500 1.00 17.61 ? 214 TYR A OH 1 ATOM 1673 N N . GLY A 1 215 ? -0.256 -16.536 34.218 1.00 12.34 ? 215 GLY A N 1 ATOM 1674 C CA . GLY A 1 215 ? -0.218 -15.657 35.376 1.00 11.70 ? 215 GLY A CA 1 ATOM 1675 C C . GLY A 1 215 ? -0.374 -16.324 36.723 1.00 11.57 ? 215 GLY A C 1 ATOM 1676 O O . GLY A 1 215 ? -0.691 -17.491 36.816 1.00 12.68 ? 215 GLY A O 1 ATOM 1677 N N . ALA A 1 216 ? -0.136 -15.561 37.775 1.00 12.58 ? 216 ALA A N 1 ATOM 1678 C CA . ALA A 1 216 ? -0.170 -16.036 39.139 1.00 13.95 ? 216 ALA A CA 1 ATOM 1679 C C . ALA A 1 216 ? -1.079 -15.107 39.924 1.00 14.01 ? 216 ALA A C 1 ATOM 1680 O O . ALA A 1 216 ? -0.790 -13.933 40.093 1.00 15.11 ? 216 ALA A O 1 ATOM 1681 C CB . ALA A 1 216 ? 1.231 -16.021 39.764 1.00 13.60 ? 216 ALA A CB 1 ATOM 1682 N N . GLN A 1 217 ? -2.185 -15.647 40.388 1.00 14.78 ? 217 GLN A N 1 ATOM 1683 C CA . GLN A 1 217 ? -3.230 -14.832 41.071 1.00 14.46 ? 217 GLN A CA 1 ATOM 1684 C C . GLN A 1 217 ? -3.742 -15.627 42.267 1.00 14.14 ? 217 GLN A C 1 ATOM 1685 O O . GLN A 1 217 ? -4.439 -16.603 42.108 1.00 14.97 ? 217 GLN A O 1 ATOM 1686 C CB . GLN A 1 217 ? -4.354 -14.493 40.092 1.00 14.48 ? 217 GLN A CB 1 ATOM 1687 C CG . GLN A 1 217 ? -3.910 -13.691 38.816 1.00 14.70 ? 217 GLN A CG 1 ATOM 1688 C CD . GLN A 1 217 ? -3.390 -12.285 39.140 1.00 14.52 ? 217 GLN A CD 1 ATOM 1689 O OE1 . GLN A 1 217 ? -3.631 -11.754 40.218 1.00 17.59 ? 217 GLN A OE1 1 ATOM 1690 N NE2 . GLN A 1 217 ? -2.671 -11.687 38.210 1.00 16.53 ? 217 GLN A NE2 1 ATOM 1691 N N . THR A 1 218 ? -3.369 -15.227 43.473 1.00 15.69 ? 218 THR A N 1 ATOM 1692 C CA . THR A 1 218 ? -3.741 -16.009 44.652 1.00 16.41 ? 218 THR A CA 1 ATOM 1693 C C . THR A 1 218 ? -5.036 -15.497 45.295 1.00 16.80 ? 218 THR A C 1 ATOM 1694 O O . THR A 1 218 ? -5.575 -16.137 46.189 1.00 17.90 ? 218 THR A O 1 ATOM 1695 C CB . THR A 1 218 ? -2.641 -15.983 45.697 1.00 16.14 ? 218 THR A CB 1 ATOM 1696 O OG1 . THR A 1 218 ? -2.465 -14.645 46.156 1.00 18.47 ? 218 THR A OG1 1 ATOM 1697 C CG2 . THR A 1 218 ? -1.313 -16.470 45.110 1.00 14.89 ? 218 THR A CG2 1 ATOM 1698 N N . PHE A 1 219 ? -5.531 -14.358 44.835 1.00 16.39 ? 219 PHE A N 1 ATOM 1699 C CA . PHE A 1 219 ? -6.762 -13.780 45.401 1.00 15.09 ? 219 PHE A CA 1 ATOM 1700 C C . PHE A 1 219 ? -7.985 -14.678 45.182 1.00 15.40 ? 219 PHE A C 1 ATOM 1701 O O . PHE A 1 219 ? -8.213 -15.199 44.088 1.00 14.58 ? 219 PHE A O 1 ATOM 1702 C CB . PHE A 1 219 ? -7.013 -12.378 44.830 1.00 14.59 ? 219 PHE A CB 1 ATOM 1703 C CG . PHE A 1 219 ? -8.269 -11.701 45.370 1.00 15.12 ? 219 PHE A CG 1 ATOM 1704 C CD1 . PHE A 1 219 ? -8.319 -11.254 46.693 1.00 14.01 ? 219 PHE A CD1 1 ATOM 1705 C CD2 . PHE A 1 219 ? -9.401 -11.553 44.569 1.00 12.97 ? 219 PHE A CD2 1 ATOM 1706 C CE1 . PHE A 1 219 ? -9.474 -10.647 47.204 1.00 15.93 ? 219 PHE A CE1 1 ATOM 1707 C CE2 . PHE A 1 219 ? -10.556 -10.945 45.074 1.00 13.05 ? 219 PHE A CE2 1 ATOM 1708 C CZ . PHE A 1 219 ? -10.590 -10.498 46.382 1.00 13.52 ? 219 PHE A CZ 1 ATOM 1709 N N . PHE A 1 220 ? -8.768 -14.847 46.245 1.00 15.59 ? 220 PHE A N 1 ATOM 1710 C CA . PHE A 1 220 ? -10.112 -15.357 46.132 1.00 16.36 ? 220 PHE A CA 1 ATOM 1711 C C . PHE A 1 220 ? -11.036 -14.537 47.005 1.00 16.42 ? 220 PHE A C 1 ATOM 1712 O O . PHE A 1 220 ? -10.600 -13.944 47.996 1.00 17.27 ? 220 PHE A O 1 ATOM 1713 C CB . PHE A 1 220 ? -10.215 -16.857 46.452 1.00 16.41 ? 220 PHE A CB 1 ATOM 1714 C CG . PHE A 1 220 ? -10.144 -17.184 47.928 1.00 16.61 ? 220 PHE A CG 1 ATOM 1715 C CD1 . PHE A 1 220 ? -11.299 -17.218 48.712 1.00 17.57 ? 220 PHE A CD1 1 ATOM 1716 C CD2 . PHE A 1 220 ? -8.930 -17.466 48.525 1.00 14.59 ? 220 PHE A CD2 1 ATOM 1717 C CE1 . PHE A 1 220 ? -11.248 -17.500 50.066 1.00 15.31 ? 220 PHE A CE1 1 ATOM 1718 C CE2 . PHE A 1 220 ? -8.871 -17.762 49.875 1.00 14.59 ? 220 PHE A CE2 1 ATOM 1719 C CZ . PHE A 1 220 ? -10.050 -17.796 50.646 1.00 17.34 ? 220 PHE A CZ 1 ATOM 1720 N N . LEU A 1 221 ? -12.301 -14.527 46.608 1.00 16.08 ? 221 LEU A N 1 ATOM 1721 C CA . LEU A 1 221 ? -13.399 -13.815 47.266 1.00 15.92 ? 221 LEU A CA 1 ATOM 1722 C C . LEU A 1 221 ? -14.408 -14.890 47.669 1.00 15.57 ? 221 LEU A C 1 ATOM 1723 O O . LEU A 1 221 ? -14.624 -15.843 46.936 1.00 13.78 ? 221 LEU A O 1 ATOM 1724 C CB . LEU A 1 221 ? -14.060 -12.819 46.271 1.00 15.07 ? 221 LEU A CB 1 ATOM 1725 C CG . LEU A 1 221 ? -15.296 -11.946 46.598 1.00 17.05 ? 221 LEU A CG 1 ATOM 1726 C CD1 . LEU A 1 221 ? -15.291 -10.729 45.675 1.00 17.75 ? 221 LEU A CD1 1 ATOM 1727 C CD2 . LEU A 1 221 ? -16.636 -12.708 46.441 1.00 15.91 ? 221 LEU A CD2 1 ATOM 1728 N N . CYS A 1 222 ? -15.041 -14.710 48.831 1.00 16.64 ? 222 CYS A N 1 ATOM 1729 C CA . CYS A 1 222 ? -16.058 -15.640 49.302 1.00 16.19 ? 222 CYS A CA 1 ATOM 1730 C C . CYS A 1 222 ? -17.335 -14.848 49.623 1.00 15.69 ? 222 CYS A C 1 ATOM 1731 O O . CYS A 1 222 ? -17.312 -13.943 50.425 1.00 15.41 ? 222 CYS A O 1 ATOM 1732 C CB . CYS A 1 222 ? -15.557 -16.392 50.534 1.00 16.67 ? 222 CYS A CB 1 ATOM 1733 S SG . CYS A 1 222 ? -16.724 -17.551 51.274 1.00 18.69 ? 222 CYS A SG 1 ATOM 1734 N N . LEU A 1 223 ? -18.428 -15.179 48.963 1.00 15.21 ? 223 LEU A N 1 ATOM 1735 C CA . LEU A 1 223 ? -19.723 -14.620 49.368 1.00 14.74 ? 223 LEU A CA 1 ATOM 1736 C C . LEU A 1 223 ? -20.247 -15.465 50.541 1.00 14.34 ? 223 LEU A C 1 ATOM 1737 O O . LEU A 1 223 ? -20.600 -16.622 50.376 1.00 13.53 ? 223 LEU A O 1 ATOM 1738 C CB . LEU A 1 223 ? -20.698 -14.571 48.184 1.00 13.76 ? 223 LEU A CB 1 ATOM 1739 C CG . LEU A 1 223 ? -22.175 -14.273 48.552 1.00 14.23 ? 223 LEU A CG 1 ATOM 1740 C CD1 . LEU A 1 223 ? -22.364 -12.874 49.069 1.00 9.01 ? 223 LEU A CD1 1 ATOM 1741 C CD2 . LEU A 1 223 ? -23.087 -14.530 47.370 1.00 14.35 ? 223 LEU A CD2 1 ATOM 1742 N N . GLU A 1 224 ? -20.268 -14.875 51.728 1.00 15.56 ? 224 GLU A N 1 ATOM 1743 C CA . GLU A 1 224 ? -20.643 -15.583 52.957 1.00 17.45 ? 224 GLU A CA 1 ATOM 1744 C C . GLU A 1 224 ? -22.087 -16.074 52.967 1.00 17.79 ? 224 GLU A C 1 ATOM 1745 O O . GLU A 1 224 ? -22.336 -17.206 53.353 1.00 17.69 ? 224 GLU A O 1 ATOM 1746 C CB . GLU A 1 224 ? -20.401 -14.687 54.180 1.00 17.76 ? 224 GLU A CB 1 ATOM 1747 C CG . GLU A 1 224 ? -18.920 -14.335 54.338 1.00 18.07 ? 224 GLU A CG 1 ATOM 1748 C CD . GLU A 1 224 ? -18.691 -13.127 55.193 1.00 19.51 ? 224 GLU A CD 1 ATOM 1749 O OE1 . GLU A 1 224 ? -19.329 -12.968 56.273 1.00 19.37 ? 224 GLU A OE1 1 ATOM 1750 O OE2 . GLU A 1 224 ? -17.816 -12.344 54.792 1.00 22.46 ? 224 GLU A OE2 1 ATOM 1751 N N . ASP A 1 225 ? -23.017 -15.210 52.552 1.00 20.12 ? 225 ASP A N 1 ATOM 1752 C CA . ASP A 1 225 ? -24.473 -15.488 52.585 1.00 20.48 ? 225 ASP A CA 1 ATOM 1753 C C . ASP A 1 225 ? -25.284 -14.503 51.713 1.00 19.84 ? 225 ASP A C 1 ATOM 1754 O O . ASP A 1 225 ? -24.720 -13.614 51.078 1.00 17.94 ? 225 ASP A O 1 ATOM 1755 C CB . ASP A 1 225 ? -24.988 -15.535 54.055 1.00 22.47 ? 225 ASP A CB 1 ATOM 1756 C CG . ASP A 1 225 ? -24.779 -14.227 54.833 1.00 25.82 ? 225 ASP A CG 1 ATOM 1757 O OD1 . ASP A 1 225 ? -25.245 -13.138 54.392 1.00 28.15 ? 225 ASP A OD1 1 ATOM 1758 O OD2 . ASP A 1 225 ? -24.174 -14.279 55.941 1.00 30.94 ? 225 ASP A OD2 1 ATOM 1759 N N . ALA A 1 226 ? -26.613 -14.660 51.682 1.00 19.84 ? 226 ALA A N 1 ATOM 1760 C CA . ALA A 1 226 ? -27.473 -13.831 50.837 1.00 19.31 ? 226 ALA A CA 1 ATOM 1761 C C . ALA A 1 226 ? -27.504 -12.353 51.241 1.00 19.43 ? 226 ALA A C 1 ATOM 1762 O O . ALA A 1 226 ? -27.933 -11.507 50.476 1.00 19.09 ? 226 ALA A O 1 ATOM 1763 C CB . ALA A 1 226 ? -28.949 -14.437 50.782 1.00 19.66 ? 226 ALA A CB 1 ATOM 1764 N N . SER A 1 227 ? -27.046 -12.014 52.437 1.00 19.59 ? 227 SER A N 1 ATOM 1765 C CA . SER A 1 227 ? -26.957 -10.606 52.804 1.00 20.24 ? 227 SER A CA 1 ATOM 1766 C C . SER A 1 227 ? -25.969 -9.803 51.961 1.00 19.62 ? 227 SER A C 1 ATOM 1767 O O . SER A 1 227 ? -26.057 -8.573 51.924 1.00 18.96 ? 227 SER A O 1 ATOM 1768 C CB . SER A 1 227 ? -26.647 -10.413 54.291 1.00 20.82 ? 227 SER A CB 1 ATOM 1769 O OG . SER A 1 227 ? -25.359 -10.908 54.609 1.00 24.52 ? 227 SER A OG 1 ATOM 1770 N N . GLY A 1 228 ? -25.041 -10.493 51.284 1.00 19.69 ? 228 GLY A N 1 ATOM 1771 C CA . GLY A 1 228 ? -23.982 -9.821 50.541 1.00 18.02 ? 228 GLY A CA 1 ATOM 1772 C C . GLY A 1 228 ? -22.650 -9.809 51.254 1.00 17.98 ? 228 GLY A C 1 ATOM 1773 O O . GLY A 1 228 ? -21.607 -9.616 50.619 1.00 15.86 ? 228 GLY A O 1 ATOM 1774 N N . LEU A 1 229 ? -22.668 -10.023 52.572 1.00 17.90 ? 229 LEU A N 1 ATOM 1775 C CA . LEU A 1 229 ? -21.416 -10.069 53.342 1.00 16.43 ? 229 LEU A CA 1 ATOM 1776 C C . LEU A 1 229 ? -20.473 -11.086 52.701 1.00 15.40 ? 229 LEU A C 1 ATOM 1777 O O . LEU A 1 229 ? -20.851 -12.211 52.347 1.00 14.86 ? 229 LEU A O 1 ATOM 1778 C CB . LEU A 1 229 ? -21.621 -10.363 54.844 1.00 16.54 ? 229 LEU A CB 1 ATOM 1779 C CG . LEU A 1 229 ? -22.527 -9.422 55.665 1.00 17.66 ? 229 LEU A CG 1 ATOM 1780 C CD1 . LEU A 1 229 ? -22.737 -9.950 57.085 1.00 16.89 ? 229 LEU A CD1 1 ATOM 1781 C CD2 . LEU A 1 229 ? -22.017 -7.997 55.731 1.00 17.98 ? 229 LEU A CD2 1 ATOM 1782 N N . SER A 1 230 ? -19.238 -10.654 52.549 1.00 14.08 ? 230 SER A N 1 ATOM 1783 C CA . SER A 1 230 ? -18.274 -11.296 51.667 1.00 13.62 ? 230 SER A CA 1 ATOM 1784 C C . SER A 1 230 ? -16.924 -10.946 52.257 1.00 13.22 ? 230 SER A C 1 ATOM 1785 O O . SER A 1 230 ? -16.829 -9.995 52.984 1.00 11.68 ? 230 SER A O 1 ATOM 1786 C CB . SER A 1 230 ? -18.363 -10.657 50.283 1.00 12.98 ? 230 SER A CB 1 ATOM 1787 O OG . SER A 1 230 ? -19.467 -11.119 49.560 1.00 15.63 ? 230 SER A OG 1 ATOM 1788 N N . PHE A 1 231 ? -15.889 -11.729 51.964 1.00 13.94 ? 231 PHE A N 1 ATOM 1789 C CA . PHE A 1 231 ? -14.552 -11.364 52.392 1.00 13.37 ? 231 PHE A CA 1 ATOM 1790 C C . PHE A 1 231 ? -13.607 -11.942 51.360 1.00 13.40 ? 231 PHE A C 1 ATOM 1791 O O . PHE A 1 231 ? -14.042 -12.652 50.450 1.00 12.75 ? 231 PHE A O 1 ATOM 1792 C CB . PHE A 1 231 ? -14.246 -11.878 53.811 1.00 14.34 ? 231 PHE A CB 1 ATOM 1793 C CG . PHE A 1 231 ? -13.897 -13.334 53.856 1.00 14.42 ? 231 PHE A CG 1 ATOM 1794 C CD1 . PHE A 1 231 ? -12.565 -13.733 53.973 1.00 14.66 ? 231 PHE A CD1 1 ATOM 1795 C CD2 . PHE A 1 231 ? -14.902 -14.310 53.761 1.00 13.88 ? 231 PHE A CD2 1 ATOM 1796 C CE1 . PHE A 1 231 ? -12.227 -15.086 53.967 1.00 15.80 ? 231 PHE A CE1 1 ATOM 1797 C CE2 . PHE A 1 231 ? -14.585 -15.637 53.802 1.00 16.77 ? 231 PHE A CE2 1 ATOM 1798 C CZ . PHE A 1 231 ? -13.232 -16.044 53.897 1.00 15.75 ? 231 PHE A CZ 1 ATOM 1799 N N . GLY A 1 232 ? -12.339 -11.539 51.422 1.00 12.42 ? 232 GLY A N 1 ATOM 1800 C CA . GLY A 1 232 ? -11.377 -12.043 50.452 1.00 11.81 ? 232 GLY A CA 1 ATOM 1801 C C . GLY A 1 232 ? -10.057 -12.340 51.133 1.00 11.73 ? 232 GLY A C 1 ATOM 1802 O O . GLY A 1 232 ? -9.817 -11.878 52.232 1.00 11.31 ? 232 GLY A O 1 ATOM 1803 N N . VAL A 1 233 ? -9.229 -13.167 50.508 1.00 12.09 ? 233 VAL A N 1 ATOM 1804 C CA . VAL A 1 233 ? -7.912 -13.517 51.068 1.00 12.69 ? 233 VAL A CA 1 ATOM 1805 C C . VAL A 1 233 ? -6.915 -13.352 49.950 1.00 13.14 ? 233 VAL A C 1 ATOM 1806 O O . VAL A 1 233 ? -7.188 -13.777 48.816 1.00 12.23 ? 233 VAL A O 1 ATOM 1807 C CB . VAL A 1 233 ? -7.849 -14.978 51.634 1.00 13.26 ? 233 VAL A CB 1 ATOM 1808 C CG1 . VAL A 1 233 ? -6.423 -15.350 52.059 1.00 11.65 ? 233 VAL A CG1 1 ATOM 1809 C CG2 . VAL A 1 233 ? -8.768 -15.143 52.824 1.00 11.59 ? 233 VAL A CG2 1 ATOM 1810 N N . PHE A 1 234 ? -5.776 -12.733 50.267 1.00 13.61 ? 234 PHE A N 1 ATOM 1811 C CA . PHE A 1 234 ? -4.659 -12.636 49.347 1.00 13.03 ? 234 PHE A CA 1 ATOM 1812 C C . PHE A 1 234 ? -3.339 -13.149 49.999 1.00 13.54 ? 234 PHE A C 1 ATOM 1813 O O . PHE A 1 234 ? -2.944 -12.701 51.085 1.00 11.82 ? 234 PHE A O 1 ATOM 1814 C CB . PHE A 1 234 ? -4.474 -11.183 48.906 1.00 13.53 ? 234 PHE A CB 1 ATOM 1815 C CG . PHE A 1 234 ? -3.243 -10.950 48.052 1.00 13.90 ? 234 PHE A CG 1 ATOM 1816 C CD1 . PHE A 1 234 ? -3.108 -11.592 46.844 1.00 14.36 ? 234 PHE A CD1 1 ATOM 1817 C CD2 . PHE A 1 234 ? -2.228 -10.096 48.482 1.00 13.95 ? 234 PHE A CD2 1 ATOM 1818 C CE1 . PHE A 1 234 ? -1.977 -11.415 46.047 1.00 17.15 ? 234 PHE A CE1 1 ATOM 1819 C CE2 . PHE A 1 234 ? -1.088 -9.897 47.700 1.00 15.64 ? 234 PHE A CE2 1 ATOM 1820 C CZ . PHE A 1 234 ? -0.963 -10.571 46.465 1.00 13.06 ? 234 PHE A CZ 1 ATOM 1821 N N . LEU A 1 235 ? -2.687 -14.093 49.323 1.00 12.40 ? 235 LEU A N 1 ATOM 1822 C CA . LEU A 1 235 ? -1.367 -14.565 49.734 1.00 12.72 ? 235 LEU A CA 1 ATOM 1823 C C . LEU A 1 235 ? -0.327 -13.853 48.863 1.00 12.64 ? 235 LEU A C 1 ATOM 1824 O O . LEU A 1 235 ? -0.317 -14.026 47.647 1.00 13.48 ? 235 LEU A O 1 ATOM 1825 C CB . LEU A 1 235 ? -1.246 -16.101 49.648 1.00 12.93 ? 235 LEU A CB 1 ATOM 1826 C CG . LEU A 1 235 ? 0.182 -16.686 49.824 1.00 11.96 ? 235 LEU A CG 1 ATOM 1827 C CD1 . LEU A 1 235 ? 0.713 -16.283 51.168 1.00 6.52 ? 235 LEU A CD1 1 ATOM 1828 C CD2 . LEU A 1 235 ? 0.228 -18.208 49.654 1.00 11.35 ? 235 LEU A CD2 1 ATOM 1829 N N . MET A 1 236 ? 0.476 -12.998 49.499 1.00 13.94 ? 236 MET A N 1 ATOM 1830 C CA . MET A 1 236 ? 1.614 -12.310 48.890 1.00 14.86 ? 236 MET A CA 1 ATOM 1831 C C . MET A 1 236 ? 2.858 -13.217 48.892 1.00 15.95 ? 236 MET A C 1 ATOM 1832 O O . MET A 1 236 ? 3.686 -13.182 49.804 1.00 15.82 ? 236 MET A O 1 ATOM 1833 C CB . MET A 1 236 ? 1.915 -11.010 49.640 1.00 14.62 ? 236 MET A CB 1 ATOM 1834 C CG . MET A 1 236 ? 3.066 -10.161 49.014 1.00 16.10 ? 236 MET A CG 1 ATOM 1835 S SD . MET A 1 236 ? 2.792 -9.519 47.345 1.00 21.51 ? 236 MET A SD 1 ATOM 1836 C CE . MET A 1 236 ? 2.218 -7.909 47.887 1.00 17.52 ? 236 MET A CE 1 ATOM 1837 N N . ASN A 1 237 ? 2.951 -14.043 47.856 1.00 17.17 ? 237 ASN A N 1 ATOM 1838 C CA . ASN A 1 237 ? 4.022 -15.035 47.719 1.00 16.36 ? 237 ASN A CA 1 ATOM 1839 C C . ASN A 1 237 ? 4.149 -15.276 46.212 1.00 16.96 ? 237 ASN A C 1 ATOM 1840 O O . ASN A 1 237 ? 3.143 -15.446 45.514 1.00 16.31 ? 237 ASN A O 1 ATOM 1841 C CB . ASN A 1 237 ? 3.643 -16.306 48.512 1.00 16.38 ? 237 ASN A CB 1 ATOM 1842 C CG . ASN A 1 237 ? 4.725 -17.396 48.503 1.00 15.36 ? 237 ASN A CG 1 ATOM 1843 O OD1 . ASN A 1 237 ? 4.861 -18.122 47.544 1.00 14.34 ? 237 ASN A OD1 1 ATOM 1844 N ND2 . ASN A 1 237 ? 5.360 -17.608 49.643 1.00 13.96 ? 237 ASN A ND2 1 ATOM 1845 N N . SER A 1 238 ? 5.381 -15.208 45.701 1.00 16.43 ? 238 SER A N 1 ATOM 1846 C CA . SER A 1 238 ? 5.647 -15.407 44.284 1.00 16.83 ? 238 SER A CA 1 ATOM 1847 C C . SER A 1 238 ? 6.299 -16.781 43.910 1.00 17.87 ? 238 SER A C 1 ATOM 1848 O O . SER A 1 238 ? 6.751 -16.971 42.780 1.00 17.67 ? 238 SER A O 1 ATOM 1849 C CB . SER A 1 238 ? 6.552 -14.273 43.784 1.00 17.19 ? 238 SER A CB 1 ATOM 1850 O OG . SER A 1 238 ? 7.760 -14.224 44.522 1.00 15.96 ? 238 SER A OG 1 ATOM 1851 N N . ASN A 1 239 ? 6.382 -17.705 44.866 1.00 16.48 ? 239 ASN A N 1 ATOM 1852 C CA . ASN A 1 239 ? 6.937 -19.014 44.597 1.00 16.27 ? 239 ASN A CA 1 ATOM 1853 C C . ASN A 1 239 ? 5.892 -19.931 43.995 1.00 16.23 ? 239 ASN A C 1 ATOM 1854 O O . ASN A 1 239 ? 4.673 -19.614 44.057 1.00 15.89 ? 239 ASN A O 1 ATOM 1855 C CB . ASN A 1 239 ? 7.520 -19.603 45.891 1.00 16.16 ? 239 ASN A CB 1 ATOM 1856 C CG . ASN A 1 239 ? 8.773 -18.861 46.336 1.00 17.41 ? 239 ASN A CG 1 ATOM 1857 O OD1 . ASN A 1 239 ? 9.890 -19.275 46.037 1.00 22.01 ? 239 ASN A OD1 1 ATOM 1858 N ND2 . ASN A 1 239 ? 8.595 -17.759 47.026 1.00 15.99 ? 239 ASN A ND2 1 ATOM 1859 N N . ALA A 1 240 ? 6.339 -21.030 43.391 1.00 15.35 ? 240 ALA A N 1 ATOM 1860 C CA . ALA A 1 240 ? 5.403 -22.065 42.908 1.00 15.81 ? 240 ALA A CA 1 ATOM 1861 C C . ALA A 1 240 ? 4.550 -22.549 44.060 1.00 16.02 ? 240 ALA A C 1 ATOM 1862 O O . ALA A 1 240 ? 5.019 -22.706 45.163 1.00 16.10 ? 240 ALA A O 1 ATOM 1863 C CB . ALA A 1 240 ? 6.119 -23.247 42.270 1.00 16.23 ? 240 ALA A CB 1 ATOM 1864 N N . MET A 1 241 ? 3.296 -22.835 43.778 1.00 16.14 ? 241 MET A N 1 ATOM 1865 C CA . MET A 1 241 ? 2.398 -23.194 44.835 1.00 17.06 ? 241 MET A CA 1 ATOM 1866 C C . MET A 1 241 ? 1.212 -23.910 44.249 1.00 16.52 ? 241 MET A C 1 ATOM 1867 O O . MET A 1 241 ? 1.056 -23.987 43.029 1.00 15.85 ? 241 MET A O 1 ATOM 1868 C CB . MET A 1 241 ? 1.935 -21.926 45.557 1.00 17.00 ? 241 MET A CB 1 ATOM 1869 C CG . MET A 1 241 ? 0.775 -21.177 44.854 1.00 18.74 ? 241 MET A CG 1 ATOM 1870 S SD . MET A 1 241 ? 0.122 -19.847 45.889 1.00 19.46 ? 241 MET A SD 1 ATOM 1871 C CE . MET A 1 241 ? 1.597 -18.821 46.030 1.00 16.30 ? 241 MET A CE 1 ATOM 1872 N N . GLU A 1 242 ? 0.389 -24.453 45.134 1.00 17.56 ? 242 GLU A N 1 ATOM 1873 C CA . GLU A 1 242 ? -0.909 -24.943 44.742 1.00 17.40 ? 242 GLU A CA 1 ATOM 1874 C C . GLU A 1 242 ? -1.950 -24.656 45.812 1.00 17.76 ? 242 GLU A C 1 ATOM 1875 O O . GLU A 1 242 ? -1.642 -24.436 46.979 1.00 18.44 ? 242 GLU A O 1 ATOM 1876 C CB . GLU A 1 242 ? -0.849 -26.418 44.348 1.00 17.63 ? 242 GLU A CB 1 ATOM 1877 C CG . GLU A 1 242 ? -0.444 -27.379 45.447 1.00 19.97 ? 242 GLU A CG 1 ATOM 1878 C CD . GLU A 1 242 ? -0.025 -28.725 44.887 1.00 23.55 ? 242 GLU A CD 1 ATOM 1879 O OE1 . GLU A 1 242 ? -0.013 -28.862 43.640 1.00 23.92 ? 242 GLU A OE1 1 ATOM 1880 O OE2 . GLU A 1 242 ? 0.277 -29.648 45.681 1.00 24.74 ? 242 GLU A OE2 1 ATOM 1881 N N . VAL A 1 243 ? -3.198 -24.614 45.389 1.00 17.28 ? 243 VAL A N 1 ATOM 1882 C CA . VAL A 1 243 ? -4.273 -24.270 46.282 1.00 16.52 ? 243 VAL A CA 1 ATOM 1883 C C . VAL A 1 243 ? -5.164 -25.476 46.260 1.00 15.92 ? 243 VAL A C 1 ATOM 1884 O O . VAL A 1 243 ? -5.611 -25.922 45.206 1.00 15.13 ? 243 VAL A O 1 ATOM 1885 C CB . VAL A 1 243 ? -4.990 -22.985 45.795 1.00 17.61 ? 243 VAL A CB 1 ATOM 1886 C CG1 . VAL A 1 243 ? -6.392 -22.862 46.401 1.00 19.81 ? 243 VAL A CG1 1 ATOM 1887 C CG2 . VAL A 1 243 ? -4.166 -21.792 46.143 1.00 17.16 ? 243 VAL A CG2 1 ATOM 1888 N N . VAL A 1 244 ? -5.417 -26.014 47.438 1.00 15.57 ? 244 VAL A N 1 ATOM 1889 C CA . VAL A 1 244 ? -6.153 -27.234 47.548 1.00 15.20 ? 244 VAL A CA 1 ATOM 1890 C C . VAL A 1 244 ? -7.510 -26.863 48.107 1.00 15.01 ? 244 VAL A C 1 ATOM 1891 O O . VAL A 1 244 ? -7.602 -26.235 49.141 1.00 15.19 ? 244 VAL A O 1 ATOM 1892 C CB . VAL A 1 244 ? -5.435 -28.215 48.484 1.00 15.53 ? 244 VAL A CB 1 ATOM 1893 C CG1 . VAL A 1 244 ? -6.169 -29.554 48.529 1.00 14.59 ? 244 VAL A CG1 1 ATOM 1894 C CG2 . VAL A 1 244 ? -3.954 -28.388 48.055 1.00 17.73 ? 244 VAL A CG2 1 ATOM 1895 N N . LEU A 1 245 ? -8.559 -27.285 47.436 1.00 15.41 ? 245 LEU A N 1 ATOM 1896 C CA . LEU A 1 245 ? -9.926 -26.915 47.833 1.00 16.31 ? 245 LEU A CA 1 ATOM 1897 C C . LEU A 1 245 ? -10.594 -28.184 48.256 1.00 16.54 ? 245 LEU A C 1 ATOM 1898 O O . LEU A 1 245 ? -10.415 -29.209 47.609 1.00 16.68 ? 245 LEU A O 1 ATOM 1899 C CB . LEU A 1 245 ? -10.692 -26.274 46.663 1.00 15.65 ? 245 LEU A CB 1 ATOM 1900 C CG . LEU A 1 245 ? -10.097 -25.056 45.906 1.00 17.49 ? 245 LEU A CG 1 ATOM 1901 C CD1 . LEU A 1 245 ? -11.146 -24.523 44.914 1.00 18.50 ? 245 LEU A CD1 1 ATOM 1902 C CD2 . LEU A 1 245 ? -9.708 -23.918 46.820 1.00 18.88 ? 245 LEU A CD2 1 ATOM 1903 N N . GLN A 1 246 ? -11.362 -28.140 49.340 1.00 16.77 ? 246 GLN A N 1 ATOM 1904 C CA . GLN A 1 246 ? -12.063 -29.331 49.797 1.00 17.01 ? 246 GLN A CA 1 ATOM 1905 C C . GLN A 1 246 ? -13.454 -28.988 50.403 1.00 17.79 ? 246 GLN A C 1 ATOM 1906 O O . GLN A 1 246 ? -13.669 -27.860 50.810 1.00 18.04 ? 246 GLN A O 1 ATOM 1907 C CB . GLN A 1 246 ? -11.199 -30.098 50.770 1.00 17.16 ? 246 GLN A CB 1 ATOM 1908 C CG . GLN A 1 246 ? -11.100 -29.549 52.180 1.00 15.89 ? 246 GLN A CG 1 ATOM 1909 C CD . GLN A 1 246 ? -10.016 -30.293 52.929 1.00 16.91 ? 246 GLN A CD 1 ATOM 1910 O OE1 . GLN A 1 246 ? -8.840 -30.170 52.586 1.00 16.52 ? 246 GLN A OE1 1 ATOM 1911 N NE2 . GLN A 1 246 ? -10.405 -31.086 53.939 1.00 15.32 ? 246 GLN A NE2 1 ATOM 1912 N N . PRO A 1 247 ? -14.373 -29.962 50.478 1.00 18.21 ? 247 PRO A N 1 ATOM 1913 C CA . PRO A 1 247 ? -15.788 -29.671 50.784 1.00 19.42 ? 247 PRO A CA 1 ATOM 1914 C C . PRO A 1 247 ? -16.078 -29.341 52.225 1.00 19.84 ? 247 PRO A C 1 ATOM 1915 O O . PRO A 1 247 ? -17.225 -29.083 52.550 1.00 21.09 ? 247 PRO A O 1 ATOM 1916 C CB . PRO A 1 247 ? -16.517 -30.970 50.401 1.00 19.03 ? 247 PRO A CB 1 ATOM 1917 C CG . PRO A 1 247 ? -15.507 -31.801 49.701 1.00 19.09 ? 247 PRO A CG 1 ATOM 1918 C CD . PRO A 1 247 ? -14.183 -31.391 50.253 1.00 18.97 ? 247 PRO A CD 1 ATOM 1919 N N . ALA A 1 248 ? -15.062 -29.324 53.094 1.00 20.09 ? 248 ALA A N 1 ATOM 1920 C CA . ALA A 1 248 ? -15.268 -28.951 54.499 1.00 18.91 ? 248 ALA A CA 1 ATOM 1921 C C . ALA A 1 248 ? -16.309 -27.834 54.749 1.00 20.32 ? 248 ALA A C 1 ATOM 1922 O O . ALA A 1 248 ? -17.075 -27.952 55.724 1.00 19.24 ? 248 ALA A O 1 ATOM 1923 C CB . ALA A 1 248 ? -13.963 -28.602 55.161 1.00 19.02 ? 248 ALA A CB 1 ATOM 1924 N N . PRO A 1 249 ? -16.274 -26.685 53.957 1.00 19.30 ? 249 PRO A N 1 ATOM 1925 C CA . PRO A 1 249 ? -15.345 -26.252 52.922 1.00 17.88 ? 249 PRO A CA 1 ATOM 1926 C C . PRO A 1 249 ? -14.065 -25.647 53.500 1.00 17.45 ? 249 PRO A C 1 ATOM 1927 O O . PRO A 1 249 ? -14.078 -25.077 54.579 1.00 16.89 ? 249 PRO A O 1 ATOM 1928 C CB . PRO A 1 249 ? -16.137 -25.179 52.184 1.00 17.96 ? 249 PRO A CB 1 ATOM 1929 C CG . PRO A 1 249 ? -16.911 -24.548 53.232 1.00 18.36 ? 249 PRO A CG 1 ATOM 1930 C CD . PRO A 1 249 ? -17.323 -25.669 54.161 1.00 18.79 ? 249 PRO A CD 1 ATOM 1931 N N . ALA A 1 250 ? -12.956 -25.795 52.786 1.00 17.15 ? 250 ALA A N 1 ATOM 1932 C CA . ALA A 1 250 ? -11.682 -25.291 53.303 1.00 16.76 ? 250 ALA A CA 1 ATOM 1933 C C . ALA A 1 250 ? -10.739 -25.057 52.156 1.00 16.71 ? 250 ALA A C 1 ATOM 1934 O O . ALA A 1 250 ? -10.931 -25.638 51.089 1.00 15.14 ? 250 ALA A O 1 ATOM 1935 C CB . ALA A 1 250 ? -11.084 -26.316 54.269 1.00 16.76 ? 250 ALA A CB 1 ATOM 1936 N N . ILE A 1 251 ? -9.710 -24.223 52.375 1.00 16.75 ? 251 ILE A N 1 ATOM 1937 C CA . ILE A 1 251 ? -8.699 -23.979 51.357 1.00 16.87 ? 251 ILE A CA 1 ATOM 1938 C C . ILE A 1 251 ? -7.322 -24.083 51.999 1.00 17.13 ? 251 ILE A C 1 ATOM 1939 O O . ILE A 1 251 ? -7.136 -23.656 53.140 1.00 16.84 ? 251 ILE A O 1 ATOM 1940 C CB . ILE A 1 251 ? -8.926 -22.637 50.548 1.00 17.54 ? 251 ILE A CB 1 ATOM 1941 C CG1 . ILE A 1 251 ? -7.713 -22.284 49.670 1.00 15.38 ? 251 ILE A CG1 1 ATOM 1942 C CG2 . ILE A 1 251 ? -9.305 -21.486 51.477 1.00 19.35 ? 251 ILE A CG2 1 ATOM 1943 C CD1 . ILE A 1 251 ? -7.954 -21.120 48.654 1.00 17.60 ? 251 ILE A CD1 1 ATOM 1944 N N . THR A 1 252 ? -6.397 -24.733 51.298 1.00 16.63 ? 252 THR A N 1 ATOM 1945 C CA . THR A 1 252 ? -5.023 -24.914 51.784 1.00 18.06 ? 252 THR A CA 1 ATOM 1946 C C . THR A 1 252 ? -4.097 -24.297 50.752 1.00 18.20 ? 252 THR A C 1 ATOM 1947 O O . THR A 1 252 ? -4.225 -24.588 49.555 1.00 18.26 ? 252 THR A O 1 ATOM 1948 C CB . THR A 1 252 ? -4.678 -26.407 51.974 1.00 18.07 ? 252 THR A CB 1 ATOM 1949 O OG1 . THR A 1 252 ? -5.580 -26.996 52.916 1.00 19.43 ? 252 THR A OG1 1 ATOM 1950 C CG2 . THR A 1 252 ? -3.209 -26.607 52.494 1.00 17.91 ? 252 THR A CG2 1 ATOM 1951 N N . TYR A 1 253 ? -3.217 -23.411 51.210 1.00 19.12 ? 253 TYR A N 1 ATOM 1952 C CA . TYR A 1 253 ? -2.172 -22.814 50.379 1.00 20.04 ? 253 TYR A CA 1 ATOM 1953 C C . TYR A 1 253 ? -0.893 -23.609 50.646 1.00 19.87 ? 253 TYR A C 1 ATOM 1954 O O . TYR A 1 253 ? -0.541 -23.804 51.791 1.00 19.77 ? 253 TYR A O 1 ATOM 1955 C CB . TYR A 1 253 ? -1.949 -21.338 50.750 1.00 21.39 ? 253 TYR A CB 1 ATOM 1956 C CG . TYR A 1 253 ? -3.015 -20.356 50.275 1.00 21.52 ? 253 TYR A CG 1 ATOM 1957 C CD1 . TYR A 1 253 ? -2.921 -19.755 49.029 1.00 23.85 ? 253 TYR A CD1 1 ATOM 1958 C CD2 . TYR A 1 253 ? -4.104 -20.018 51.079 1.00 24.85 ? 253 TYR A CD2 1 ATOM 1959 C CE1 . TYR A 1 253 ? -3.898 -18.824 48.574 1.00 24.73 ? 253 TYR A CE1 1 ATOM 1960 C CE2 . TYR A 1 253 ? -5.093 -19.097 50.635 1.00 23.33 ? 253 TYR A CE2 1 ATOM 1961 C CZ . TYR A 1 253 ? -4.976 -18.508 49.384 1.00 26.06 ? 253 TYR A CZ 1 ATOM 1962 O OH . TYR A 1 253 ? -5.937 -17.582 48.903 1.00 26.80 ? 253 TYR A OH 1 ATOM 1963 N N . ARG A 1 254 ? -0.216 -24.064 49.595 1.00 19.16 ? 254 ARG A N 1 ATOM 1964 C CA . ARG A 1 254 ? 0.937 -24.938 49.727 1.00 19.41 ? 254 ARG A CA 1 ATOM 1965 C C . ARG A 1 254 ? 2.030 -24.364 48.830 1.00 18.99 ? 254 ARG A C 1 ATOM 1966 O O . ARG A 1 254 ? 1.946 -24.507 47.626 1.00 19.22 ? 254 ARG A O 1 ATOM 1967 C CB . ARG A 1 254 ? 0.532 -26.320 49.237 1.00 19.57 ? 254 ARG A CB 1 ATOM 1968 C CG . ARG A 1 254 ? 1.441 -27.474 49.689 1.00 20.34 ? 254 ARG A CG 1 ATOM 1969 C CD . ARG A 1 254 ? 0.921 -28.763 49.123 1.00 16.24 ? 254 ARG A CD 1 ATOM 1970 N NE . ARG A 1 254 ? -0.117 -29.397 49.944 1.00 17.91 ? 254 ARG A NE 1 ATOM 1971 C CZ . ARG A 1 254 ? -1.114 -30.110 49.442 1.00 16.32 ? 254 ARG A CZ 1 ATOM 1972 N NH1 . ARG A 1 254 ? -1.236 -30.238 48.136 1.00 19.00 ? 254 ARG A NH1 1 ATOM 1973 N NH2 . ARG A 1 254 ? -1.984 -30.703 50.233 1.00 20.08 ? 254 ARG A NH2 1 ATOM 1974 N N . THR A 1 255 ? 3.025 -23.702 49.410 1.00 17.74 ? 255 THR A N 1 ATOM 1975 C CA . THR A 1 255 ? 4.043 -23.010 48.616 1.00 17.84 ? 255 THR A CA 1 ATOM 1976 C C . THR A 1 255 ? 5.482 -23.537 48.913 1.00 17.77 ? 255 THR A C 1 ATOM 1977 O O . THR A 1 255 ? 5.720 -24.141 49.944 1.00 17.87 ? 255 THR A O 1 ATOM 1978 C CB . THR A 1 255 ? 3.897 -21.479 48.784 1.00 17.64 ? 255 THR A CB 1 ATOM 1979 O OG1 . THR A 1 255 ? 4.788 -20.798 47.893 1.00 20.09 ? 255 THR A OG1 1 ATOM 1980 C CG2 . THR A 1 255 ? 4.116 -21.028 50.231 1.00 16.33 ? 255 THR A CG2 1 ATOM 1981 N N . ILE A 1 256 ? 6.417 -23.349 47.987 1.00 17.49 ? 256 ILE A N 1 ATOM 1982 C CA . ILE A 1 256 ? 7.750 -23.960 48.127 1.00 17.07 ? 256 ILE A CA 1 ATOM 1983 C C . ILE A 1 256 ? 8.844 -22.916 48.370 1.00 17.11 ? 256 ILE A C 1 ATOM 1984 O O . ILE A 1 256 ? 10.044 -23.170 48.179 1.00 18.47 ? 256 ILE A O 1 ATOM 1985 C CB . ILE A 1 256 ? 8.106 -24.903 46.922 1.00 17.03 ? 256 ILE A CB 1 ATOM 1986 C CG1 . ILE A 1 256 ? 8.286 -24.108 45.626 1.00 15.47 ? 256 ILE A CG1 1 ATOM 1987 C CG2 . ILE A 1 256 ? 7.056 -26.027 46.767 1.00 14.10 ? 256 ILE A CG2 1 ATOM 1988 C CD1 . ILE A 1 256 ? 8.633 -24.947 44.417 1.00 17.48 ? 256 ILE A CD1 1 ATOM 1989 N N . GLY A 1 257 ? 8.438 -21.730 48.791 1.00 16.78 ? 257 GLY A N 1 ATOM 1990 C CA . GLY A 1 257 ? 9.412 -20.784 49.297 1.00 15.94 ? 257 GLY A CA 1 ATOM 1991 C C . GLY A 1 257 ? 8.788 -19.563 49.890 1.00 16.19 ? 257 GLY A C 1 ATOM 1992 O O . GLY A 1 257 ? 7.556 -19.478 50.061 1.00 14.86 ? 257 GLY A O 1 ATOM 1993 N N . GLY A 1 258 ? 9.661 -18.597 50.153 1.00 15.12 ? 258 GLY A N 1 ATOM 1994 C CA . GLY A 1 258 ? 9.298 -17.290 50.601 1.00 14.90 ? 258 GLY A CA 1 ATOM 1995 C C . GLY A 1 258 ? 8.684 -17.349 51.963 1.00 16.29 ? 258 GLY A C 1 ATOM 1996 O O . GLY A 1 258 ? 9.141 -18.100 52.827 1.00 14.99 ? 258 GLY A O 1 ATOM 1997 N N . ILE A 1 259 ? 7.614 -16.561 52.155 1.00 16.45 ? 259 ILE A N 1 ATOM 1998 C CA . ILE A 1 259 ? 6.946 -16.531 53.442 1.00 17.13 ? 259 ILE A CA 1 ATOM 1999 C C . ILE A 1 259 ? 5.436 -16.539 53.233 1.00 17.59 ? 259 ILE A C 1 ATOM 2000 O O . ILE A 1 259 ? 4.939 -16.333 52.112 1.00 16.70 ? 259 ILE A O 1 ATOM 2001 C CB . ILE A 1 259 ? 7.365 -15.291 54.358 1.00 17.65 ? 259 ILE A CB 1 ATOM 2002 C CG1 . ILE A 1 259 ? 7.124 -13.948 53.667 1.00 17.12 ? 259 ILE A CG1 1 ATOM 2003 C CG2 . ILE A 1 259 ? 8.802 -15.367 54.775 1.00 18.35 ? 259 ILE A CG2 1 ATOM 2004 C CD1 . ILE A 1 259 ? 6.831 -12.758 54.646 1.00 17.27 ? 259 ILE A CD1 1 ATOM 2005 N N . LEU A 1 260 ? 4.737 -16.810 54.321 1.00 18.31 ? 260 LEU A N 1 ATOM 2006 C CA . LEU A 1 260 ? 3.301 -16.792 54.337 1.00 20.09 ? 260 LEU A CA 1 ATOM 2007 C C . LEU A 1 260 ? 2.934 -15.397 54.770 1.00 20.28 ? 260 LEU A C 1 ATOM 2008 O O . LEU A 1 260 ? 3.037 -15.065 55.928 1.00 21.37 ? 260 LEU A O 1 ATOM 2009 C CB . LEU A 1 260 ? 2.756 -17.853 55.295 1.00 20.07 ? 260 LEU A CB 1 ATOM 2010 C CG . LEU A 1 260 ? 2.797 -19.287 54.778 1.00 21.62 ? 260 LEU A CG 1 ATOM 2011 C CD1 . LEU A 1 260 ? 2.225 -20.235 55.844 1.00 20.55 ? 260 LEU A CD1 1 ATOM 2012 C CD2 . LEU A 1 260 ? 2.043 -19.425 53.416 1.00 21.34 ? 260 LEU A CD2 1 ATOM 2013 N N . ASP A 1 261 ? 2.569 -14.578 53.790 1.00 20.97 ? 261 ASP A N 1 ATOM 2014 C CA . ASP A 1 261 ? 2.277 -13.174 53.966 1.00 20.96 ? 261 ASP A CA 1 ATOM 2015 C C . ASP A 1 261 ? 0.843 -13.000 53.481 1.00 20.91 ? 261 ASP A C 1 ATOM 2016 O O . ASP A 1 261 ? 0.604 -12.925 52.268 1.00 21.54 ? 261 ASP A O 1 ATOM 2017 C CB . ASP A 1 261 ? 3.245 -12.341 53.117 1.00 20.97 ? 261 ASP A CB 1 ATOM 2018 C CG . ASP A 1 261 ? 3.117 -10.836 53.364 1.00 24.17 ? 261 ASP A CG 1 ATOM 2019 O OD1 . ASP A 1 261 ? 2.162 -10.431 54.038 1.00 27.63 ? 261 ASP A OD1 1 ATOM 2020 O OD2 . ASP A 1 261 ? 3.976 -10.049 52.893 1.00 25.07 ? 261 ASP A OD2 1 ATOM 2021 N N . PHE A 1 262 ? -0.097 -12.933 54.430 1.00 19.37 ? 262 PHE A N 1 ATOM 2022 C CA . PHE A 1 262 ? -1.542 -13.027 54.158 1.00 18.61 ? 262 PHE A CA 1 ATOM 2023 C C . PHE A 1 262 ? -2.274 -11.705 54.417 1.00 18.02 ? 262 PHE A C 1 ATOM 2024 O O . PHE A 1 262 ? -1.924 -10.970 55.343 1.00 17.49 ? 262 PHE A O 1 ATOM 2025 C CB . PHE A 1 262 ? -2.192 -14.116 55.035 1.00 17.78 ? 262 PHE A CB 1 ATOM 2026 C CG . PHE A 1 262 ? -2.118 -15.515 54.463 1.00 18.60 ? 262 PHE A CG 1 ATOM 2027 C CD1 . PHE A 1 262 ? -2.888 -15.882 53.357 1.00 15.49 ? 262 PHE A CD1 1 ATOM 2028 C CD2 . PHE A 1 262 ? -1.290 -16.480 55.047 1.00 16.64 ? 262 PHE A CD2 1 ATOM 2029 C CE1 . PHE A 1 262 ? -2.813 -17.171 52.836 1.00 16.76 ? 262 PHE A CE1 1 ATOM 2030 C CE2 . PHE A 1 262 ? -1.223 -17.777 54.514 1.00 16.84 ? 262 PHE A CE2 1 ATOM 2031 C CZ . PHE A 1 262 ? -1.977 -18.117 53.420 1.00 16.55 ? 262 PHE A CZ 1 ATOM 2032 N N . TYR A 1 263 ? -3.277 -11.417 53.586 1.00 16.90 ? 263 TYR A N 1 ATOM 2033 C CA . TYR A 1 263 ? -4.184 -10.274 53.755 1.00 17.22 ? 263 TYR A CA 1 ATOM 2034 C C . TYR A 1 263 ? -5.619 -10.806 53.776 1.00 16.96 ? 263 TYR A C 1 ATOM 2035 O O . TYR A 1 263 ? -5.938 -11.682 52.990 1.00 16.05 ? 263 TYR A O 1 ATOM 2036 C CB . TYR A 1 263 ? -4.022 -9.295 52.581 1.00 17.38 ? 263 TYR A CB 1 ATOM 2037 C CG . TYR A 1 263 ? -2.696 -8.543 52.599 1.00 17.96 ? 263 TYR A CG 1 ATOM 2038 C CD1 . TYR A 1 263 ? -2.580 -7.330 53.274 1.00 20.19 ? 263 TYR A CD1 1 ATOM 2039 C CD2 . TYR A 1 263 ? -1.570 -9.069 52.003 1.00 17.81 ? 263 TYR A CD2 1 ATOM 2040 C CE1 . TYR A 1 263 ? -1.379 -6.633 53.303 1.00 19.56 ? 263 TYR A CE1 1 ATOM 2041 C CE2 . TYR A 1 263 ? -0.345 -8.389 52.036 1.00 19.15 ? 263 TYR A CE2 1 ATOM 2042 C CZ . TYR A 1 263 ? -0.271 -7.167 52.676 1.00 17.52 ? 263 TYR A CZ 1 ATOM 2043 O OH . TYR A 1 263 ? 0.896 -6.473 52.736 1.00 15.46 ? 263 TYR A OH 1 ATOM 2044 N N . VAL A 1 264 ? -6.456 -10.297 54.686 1.00 16.29 ? 264 VAL A N 1 ATOM 2045 C CA . VAL A 1 264 ? -7.857 -10.702 54.786 1.00 15.70 ? 264 VAL A CA 1 ATOM 2046 C C . VAL A 1 264 ? -8.682 -9.413 54.689 1.00 16.11 ? 264 VAL A C 1 ATOM 2047 O O . VAL A 1 264 ? -8.448 -8.459 55.442 1.00 16.20 ? 264 VAL A O 1 ATOM 2048 C CB . VAL A 1 264 ? -8.188 -11.534 56.090 1.00 16.38 ? 264 VAL A CB 1 ATOM 2049 C CG1 . VAL A 1 264 ? -9.655 -12.014 56.106 1.00 14.33 ? 264 VAL A CG1 1 ATOM 2050 C CG2 . VAL A 1 264 ? -7.251 -12.753 56.231 1.00 15.31 ? 264 VAL A CG2 1 ATOM 2051 N N . PHE A 1 265 ? -9.607 -9.380 53.733 1.00 15.63 ? 265 PHE A N 1 ATOM 2052 C CA . PHE A 1 265 ? -10.364 -8.173 53.387 1.00 15.92 ? 265 PHE A CA 1 ATOM 2053 C C . PHE A 1 265 ? -11.806 -8.481 53.755 1.00 16.23 ? 265 PHE A C 1 ATOM 2054 O O . PHE A 1 265 ? -12.293 -9.551 53.425 1.00 16.20 ? 265 PHE A O 1 ATOM 2055 C CB . PHE A 1 265 ? -10.299 -7.877 51.862 1.00 15.67 ? 265 PHE A CB 1 ATOM 2056 C CG . PHE A 1 265 ? -8.887 -7.852 51.293 1.00 16.68 ? 265 PHE A CG 1 ATOM 2057 C CD1 . PHE A 1 265 ? -8.064 -6.768 51.511 1.00 15.30 ? 265 PHE A CD1 1 ATOM 2058 C CD2 . PHE A 1 265 ? -8.381 -8.952 50.590 1.00 17.29 ? 265 PHE A CD2 1 ATOM 2059 C CE1 . PHE A 1 265 ? -6.740 -6.758 51.039 1.00 16.56 ? 265 PHE A CE1 1 ATOM 2060 C CE2 . PHE A 1 265 ? -7.085 -8.957 50.104 1.00 18.03 ? 265 PHE A CE2 1 ATOM 2061 C CZ . PHE A 1 265 ? -6.260 -7.843 50.311 1.00 15.50 ? 265 PHE A CZ 1 ATOM 2062 N N . LEU A 1 266 ? -12.485 -7.552 54.421 1.00 17.09 ? 266 LEU A N 1 ATOM 2063 C CA . LEU A 1 266 ? -13.907 -7.709 54.662 1.00 18.00 ? 266 LEU A CA 1 ATOM 2064 C C . LEU A 1 266 ? -14.659 -6.631 53.928 1.00 17.86 ? 266 LEU A C 1 ATOM 2065 O O . LEU A 1 266 ? -14.176 -5.527 53.788 1.00 18.62 ? 266 LEU A O 1 ATOM 2066 C CB . LEU A 1 266 ? -14.246 -7.664 56.153 1.00 17.79 ? 266 LEU A CB 1 ATOM 2067 C CG . LEU A 1 266 ? -13.979 -8.893 57.018 1.00 18.85 ? 266 LEU A CG 1 ATOM 2068 C CD1 . LEU A 1 266 ? -12.507 -8.978 57.378 1.00 19.32 ? 266 LEU A CD1 1 ATOM 2069 C CD2 . LEU A 1 266 ? -14.825 -8.747 58.302 1.00 19.31 ? 266 LEU A CD2 1 ATOM 2070 N N . GLY A 1 267 ? -15.827 -6.980 53.421 1.00 17.59 ? 267 GLY A N 1 ATOM 2071 C CA . GLY A 1 267 ? -16.672 -6.019 52.733 1.00 17.40 ? 267 GLY A CA 1 ATOM 2072 C C . GLY A 1 267 ? -18.132 -6.330 53.007 1.00 16.20 ? 267 GLY A C 1 ATOM 2073 O O . GLY A 1 267 ? -18.461 -7.414 53.438 1.00 16.15 ? 267 GLY A O 1 ATOM 2074 N N . ASN A 1 268 ? -19.028 -5.386 52.744 1.00 17.65 ? 268 ASN A N 1 ATOM 2075 C CA . ASN A 1 268 ? -20.476 -5.667 52.928 1.00 16.68 ? 268 ASN A CA 1 ATOM 2076 C C . ASN A 1 268 ? -21.126 -6.265 51.705 1.00 16.81 ? 268 ASN A C 1 ATOM 2077 O O . ASN A 1 268 ? -22.284 -6.756 51.761 1.00 17.07 ? 268 ASN A O 1 ATOM 2078 C CB . ASN A 1 268 ? -21.226 -4.390 53.338 1.00 17.62 ? 268 ASN A CB 1 ATOM 2079 C CG . ASN A 1 268 ? -20.796 -3.882 54.691 1.00 20.20 ? 268 ASN A CG 1 ATOM 2080 O OD1 . ASN A 1 268 ? -20.451 -4.662 55.572 1.00 26.35 ? 268 ASN A OD1 1 ATOM 2081 N ND2 . ASN A 1 268 ? -20.791 -2.563 54.862 1.00 21.66 ? 268 ASN A ND2 1 ATOM 2082 N N . THR A 1 269 ? -20.397 -6.196 50.594 1.00 16.31 ? 269 THR A N 1 ATOM 2083 C CA . THR A 1 269 ? -20.807 -6.734 49.302 1.00 15.81 ? 269 THR A CA 1 ATOM 2084 C C . THR A 1 269 ? -19.572 -7.336 48.618 1.00 15.38 ? 269 THR A C 1 ATOM 2085 O O . THR A 1 269 ? -18.447 -6.993 48.976 1.00 15.43 ? 269 THR A O 1 ATOM 2086 C CB . THR A 1 269 ? -21.333 -5.626 48.380 1.00 15.70 ? 269 THR A CB 1 ATOM 2087 O OG1 . THR A 1 269 ? -20.319 -4.640 48.209 1.00 14.63 ? 269 THR A OG1 1 ATOM 2088 C CG2 . THR A 1 269 ? -22.604 -4.951 48.930 1.00 16.40 ? 269 THR A CG2 1 ATOM 2089 N N . PRO A 1 270 ? -19.784 -8.226 47.629 1.00 14.79 ? 270 PRO A N 1 ATOM 2090 C CA . PRO A 1 270 ? -18.667 -8.744 46.851 1.00 14.10 ? 270 PRO A CA 1 ATOM 2091 C C . PRO A 1 270 ? -17.838 -7.648 46.211 1.00 14.96 ? 270 PRO A C 1 ATOM 2092 O O . PRO A 1 270 ? -16.593 -7.723 46.255 1.00 13.01 ? 270 PRO A O 1 ATOM 2093 C CB . PRO A 1 270 ? -19.344 -9.650 45.806 1.00 13.95 ? 270 PRO A CB 1 ATOM 2094 C CG . PRO A 1 270 ? -20.644 -10.037 46.422 1.00 13.61 ? 270 PRO A CG 1 ATOM 2095 C CD . PRO A 1 270 ? -21.073 -8.832 47.213 1.00 14.06 ? 270 PRO A CD 1 ATOM 2096 N N . GLU A 1 271 ? -18.498 -6.621 45.659 1.00 13.06 ? 271 GLU A N 1 ATOM 2097 C CA . GLU A 1 271 ? -17.809 -5.458 45.092 1.00 13.63 ? 271 GLU A CA 1 ATOM 2098 C C . GLU A 1 271 ? -16.853 -4.738 46.061 1.00 14.24 ? 271 GLU A C 1 ATOM 2099 O O . GLU A 1 271 ? -15.718 -4.325 45.664 1.00 12.04 ? 271 GLU A O 1 ATOM 2100 C CB . GLU A 1 271 ? -18.819 -4.446 44.517 1.00 14.35 ? 271 GLU A CB 1 ATOM 2101 C CG . GLU A 1 271 ? -19.355 -4.819 43.122 1.00 16.09 ? 271 GLU A CG 1 ATOM 2102 C CD . GLU A 1 271 ? -18.262 -4.808 42.055 1.00 21.64 ? 271 GLU A CD 1 ATOM 2103 O OE1 . GLU A 1 271 ? -17.725 -3.709 41.754 1.00 22.04 ? 271 GLU A OE1 1 ATOM 2104 O OE2 . GLU A 1 271 ? -17.927 -5.904 41.542 1.00 23.19 ? 271 GLU A OE2 1 ATOM 2105 N N . GLN A 1 272 ? -17.306 -4.558 47.313 1.00 14.39 ? 272 GLN A N 1 ATOM 2106 C CA . GLN A 1 272 ? -16.462 -3.942 48.339 1.00 16.09 ? 272 GLN A CA 1 ATOM 2107 C C . GLN A 1 272 ? -15.207 -4.759 48.692 1.00 15.74 ? 272 GLN A C 1 ATOM 2108 O O . GLN A 1 272 ? -14.190 -4.182 49.059 1.00 16.50 ? 272 GLN A O 1 ATOM 2109 C CB . GLN A 1 272 ? -17.234 -3.648 49.599 1.00 16.16 ? 272 GLN A CB 1 ATOM 2110 C CG . GLN A 1 272 ? -18.271 -2.543 49.444 1.00 20.37 ? 272 GLN A CG 1 ATOM 2111 C CD . GLN A 1 272 ? -18.956 -2.223 50.738 1.00 25.99 ? 272 GLN A CD 1 ATOM 2112 O OE1 . GLN A 1 272 ? -18.472 -2.602 51.820 1.00 27.64 ? 272 GLN A OE1 1 ATOM 2113 N NE2 . GLN A 1 272 ? -20.102 -1.529 50.649 1.00 27.34 ? 272 GLN A NE2 1 ATOM 2114 N N . VAL A 1 273 ? -15.318 -6.085 48.642 1.00 15.67 ? 273 VAL A N 1 ATOM 2115 C CA . VAL A 1 273 ? -14.154 -6.961 48.772 1.00 15.15 ? 273 VAL A CA 1 ATOM 2116 C C . VAL A 1 273 ? -13.167 -6.731 47.657 1.00 14.81 ? 273 VAL A C 1 ATOM 2117 O O . VAL A 1 273 ? -11.986 -6.581 47.919 1.00 15.12 ? 273 VAL A O 1 ATOM 2118 C CB . VAL A 1 273 ? -14.518 -8.432 48.873 1.00 14.64 ? 273 VAL A CB 1 ATOM 2119 C CG1 . VAL A 1 273 ? -13.207 -9.319 48.862 1.00 12.19 ? 273 VAL A CG1 1 ATOM 2120 C CG2 . VAL A 1 273 ? -15.305 -8.636 50.139 1.00 13.81 ? 273 VAL A CG2 1 ATOM 2121 N N . VAL A 1 274 ? -13.651 -6.663 46.419 1.00 14.87 ? 274 VAL A N 1 ATOM 2122 C CA . VAL A 1 274 ? -12.772 -6.343 45.303 1.00 14.13 ? 274 VAL A CA 1 ATOM 2123 C C . VAL A 1 274 ? -12.134 -4.969 45.484 1.00 14.24 ? 274 VAL A C 1 ATOM 2124 O O . VAL A 1 274 ? -10.876 -4.831 45.305 1.00 12.14 ? 274 VAL A O 1 ATOM 2125 C CB . VAL A 1 274 ? -13.434 -6.540 43.903 1.00 15.11 ? 274 VAL A CB 1 ATOM 2126 C CG1 . VAL A 1 274 ? -12.444 -6.150 42.790 1.00 12.52 ? 274 VAL A CG1 1 ATOM 2127 C CG2 . VAL A 1 274 ? -13.882 -7.968 43.751 1.00 13.60 ? 274 VAL A CG2 1 ATOM 2128 N N . GLN A 1 275 ? -12.943 -3.970 45.884 1.00 12.82 ? 275 GLN A N 1 ATOM 2129 C CA . GLN A 1 275 ? -12.421 -2.608 46.204 1.00 14.11 ? 275 GLN A CA 1 ATOM 2130 C C . GLN A 1 275 ? -11.314 -2.614 47.291 1.00 13.81 ? 275 GLN A C 1 ATOM 2131 O O . GLN A 1 275 ? -10.324 -1.909 47.148 1.00 14.00 ? 275 GLN A O 1 ATOM 2132 C CB . GLN A 1 275 ? -13.547 -1.618 46.610 1.00 14.05 ? 275 GLN A CB 1 ATOM 2133 C CG . GLN A 1 275 ? -14.573 -1.328 45.503 1.00 14.40 ? 275 GLN A CG 1 ATOM 2134 C CD . GLN A 1 275 ? -15.872 -0.671 46.022 1.00 15.58 ? 275 GLN A CD 1 ATOM 2135 O OE1 . GLN A 1 275 ? -16.119 -0.612 47.213 1.00 18.45 ? 275 GLN A OE1 1 ATOM 2136 N NE2 . GLN A 1 275 ? -16.680 -0.189 45.117 1.00 15.86 ? 275 GLN A NE2 1 ATOM 2137 N N . GLU A 1 276 ? -11.516 -3.374 48.380 1.00 13.80 ? 276 GLU A N 1 ATOM 2138 C CA . GLU A 1 276 ? -10.515 -3.551 49.448 1.00 14.46 ? 276 GLU A CA 1 ATOM 2139 C C . GLU A 1 276 ? -9.229 -4.219 48.953 1.00 14.04 ? 276 GLU A C 1 ATOM 2140 O O . GLU A 1 276 ? -8.130 -3.778 49.287 1.00 14.45 ? 276 GLU A O 1 ATOM 2141 C CB . GLU A 1 276 ? -11.084 -4.386 50.619 1.00 15.55 ? 276 GLU A CB 1 ATOM 2142 C CG . GLU A 1 276 ? -12.151 -3.708 51.465 1.00 17.48 ? 276 GLU A CG 1 ATOM 2143 C CD . GLU A 1 276 ? -11.702 -2.388 52.074 1.00 23.43 ? 276 GLU A CD 1 ATOM 2144 O OE1 . GLU A 1 276 ? -10.475 -2.194 52.288 1.00 24.38 ? 276 GLU A OE1 1 ATOM 2145 O OE2 . GLU A 1 276 ? -12.592 -1.546 52.374 1.00 26.39 ? 276 GLU A OE2 1 ATOM 2146 N N . TYR A 1 277 ? -9.373 -5.276 48.152 1.00 13.96 ? 277 TYR A N 1 ATOM 2147 C CA . TYR A 1 277 ? -8.216 -5.923 47.517 1.00 13.15 ? 277 TYR A CA 1 ATOM 2148 C C . TYR A 1 277 ? -7.428 -4.972 46.639 1.00 13.58 ? 277 TYR A C 1 ATOM 2149 O O . TYR A 1 277 ? -6.192 -4.872 46.781 1.00 11.73 ? 277 TYR A O 1 ATOM 2150 C CB . TYR A 1 277 ? -8.632 -7.148 46.704 1.00 14.52 ? 277 TYR A CB 1 ATOM 2151 C CG . TYR A 1 277 ? -7.507 -7.811 45.911 1.00 14.03 ? 277 TYR A CG 1 ATOM 2152 C CD1 . TYR A 1 277 ? -6.335 -8.267 46.540 1.00 14.54 ? 277 TYR A CD1 1 ATOM 2153 C CD2 . TYR A 1 277 ? -7.623 -7.980 44.545 1.00 15.70 ? 277 TYR A CD2 1 ATOM 2154 C CE1 . TYR A 1 277 ? -5.302 -8.885 45.800 1.00 14.58 ? 277 TYR A CE1 1 ATOM 2155 C CE2 . TYR A 1 277 ? -6.625 -8.605 43.809 1.00 15.63 ? 277 TYR A CE2 1 ATOM 2156 C CZ . TYR A 1 277 ? -5.470 -9.041 44.433 1.00 16.72 ? 277 TYR A CZ 1 ATOM 2157 O OH . TYR A 1 277 ? -4.490 -9.627 43.645 1.00 18.46 ? 277 TYR A OH 1 ATOM 2158 N N . LEU A 1 278 ? -8.124 -4.272 45.733 1.00 12.52 ? 278 LEU A N 1 ATOM 2159 C CA . LEU A 1 278 ? -7.461 -3.366 44.792 1.00 13.94 ? 278 LEU A CA 1 ATOM 2160 C C . LEU A 1 278 ? -6.900 -2.125 45.461 1.00 14.07 ? 278 LEU A C 1 ATOM 2161 O O . LEU A 1 278 ? -5.935 -1.542 44.965 1.00 15.07 ? 278 LEU A O 1 ATOM 2162 C CB . LEU A 1 278 ? -8.360 -3.023 43.577 1.00 13.59 ? 278 LEU A CB 1 ATOM 2163 C CG . LEU A 1 278 ? -8.831 -4.269 42.801 1.00 13.89 ? 278 LEU A CG 1 ATOM 2164 C CD1 . LEU A 1 278 ? -9.687 -3.822 41.620 1.00 11.74 ? 278 LEU A CD1 1 ATOM 2165 C CD2 . LEU A 1 278 ? -7.611 -5.099 42.358 1.00 13.07 ? 278 LEU A CD2 1 ATOM 2166 N N . GLU A 1 279 ? -7.493 -1.716 46.583 1.00 15.08 ? 279 GLU A N 1 ATOM 2167 C CA . GLU A 1 279 ? -6.885 -0.687 47.432 1.00 16.63 ? 279 GLU A CA 1 ATOM 2168 C C . GLU A 1 279 ? -5.475 -1.100 47.882 1.00 16.38 ? 279 GLU A C 1 ATOM 2169 O O . GLU A 1 279 ? -4.551 -0.283 47.907 1.00 16.68 ? 279 GLU A O 1 ATOM 2170 C CB . GLU A 1 279 ? -7.752 -0.345 48.647 1.00 17.10 ? 279 GLU A CB 1 ATOM 2171 C CG . GLU A 1 279 ? -7.064 0.523 49.740 1.00 20.17 ? 279 GLU A CG 1 ATOM 2172 C CD . GLU A 1 279 ? -6.650 1.920 49.279 1.00 27.70 ? 279 GLU A CD 1 ATOM 2173 O OE1 . GLU A 1 279 ? -7.191 2.408 48.265 1.00 32.30 ? 279 GLU A OE1 1 ATOM 2174 O OE2 . GLU A 1 279 ? -5.793 2.557 49.947 1.00 29.32 ? 279 GLU A OE2 1 ATOM 2175 N N . LEU A 1 280 ? -5.330 -2.354 48.263 1.00 16.95 ? 280 LEU A N 1 ATOM 2176 C CA . LEU A 1 280 ? -4.008 -2.864 48.648 1.00 17.32 ? 280 LEU A CA 1 ATOM 2177 C C . LEU A 1 280 ? -3.063 -3.039 47.440 1.00 17.21 ? 280 LEU A C 1 ATOM 2178 O O . LEU A 1 280 ? -2.011 -2.422 47.382 1.00 17.40 ? 280 LEU A O 1 ATOM 2179 C CB . LEU A 1 280 ? -4.136 -4.161 49.477 1.00 16.17 ? 280 LEU A CB 1 ATOM 2180 C CG . LEU A 1 280 ? -2.752 -4.787 49.764 1.00 17.07 ? 280 LEU A CG 1 ATOM 2181 C CD1 . LEU A 1 280 ? -1.953 -4.044 50.862 1.00 14.42 ? 280 LEU A CD1 1 ATOM 2182 C CD2 . LEU A 1 280 ? -2.913 -6.249 50.031 1.00 17.61 ? 280 LEU A CD2 1 ATOM 2183 N N . ILE A 1 281 ? -3.422 -3.866 46.467 1.00 17.43 ? 281 ILE A N 1 ATOM 2184 C CA . ILE A 1 281 ? -2.446 -4.212 45.416 1.00 17.93 ? 281 ILE A CA 1 ATOM 2185 C C . ILE A 1 281 ? -2.301 -3.184 44.295 1.00 17.98 ? 281 ILE A C 1 ATOM 2186 O O . ILE A 1 281 ? -1.305 -3.230 43.552 1.00 18.83 ? 281 ILE A O 1 ATOM 2187 C CB . ILE A 1 281 ? -2.732 -5.572 44.724 1.00 18.31 ? 281 ILE A CB 1 ATOM 2188 C CG1 . ILE A 1 281 ? -4.149 -5.572 44.185 1.00 17.32 ? 281 ILE A CG1 1 ATOM 2189 C CG2 . ILE A 1 281 ? -2.404 -6.770 45.629 1.00 21.53 ? 281 ILE A CG2 1 ATOM 2190 C CD1 . ILE A 1 281 ? -4.209 -5.976 42.789 1.00 17.23 ? 281 ILE A CD1 1 ATOM 2191 N N . GLY A 1 282 ? -3.274 -2.279 44.140 1.00 16.94 ? 282 GLY A N 1 ATOM 2192 C CA . GLY A 1 282 ? -3.218 -1.326 43.025 1.00 16.19 ? 282 GLY A CA 1 ATOM 2193 C C . GLY A 1 282 ? -4.427 -1.440 42.099 1.00 16.39 ? 282 GLY A C 1 ATOM 2194 O O . GLY A 1 282 ? -4.718 -2.496 41.555 1.00 14.24 ? 282 GLY A O 1 ATOM 2195 N N . ARG A 1 283 ? -5.115 -0.320 41.920 1.00 16.85 ? 283 ARG A N 1 ATOM 2196 C CA . ARG A 1 283 ? -6.270 -0.263 41.039 1.00 17.60 ? 283 ARG A CA 1 ATOM 2197 C C . ARG A 1 283 ? -5.789 -0.193 39.611 1.00 17.82 ? 283 ARG A C 1 ATOM 2198 O O . ARG A 1 283 ? -4.701 0.317 39.355 1.00 19.32 ? 283 ARG A O 1 ATOM 2199 C CB . ARG A 1 283 ? -7.172 0.923 41.401 1.00 16.29 ? 283 ARG A CB 1 ATOM 2200 C CG . ARG A 1 283 ? -8.000 0.634 42.619 1.00 15.86 ? 283 ARG A CG 1 ATOM 2201 C CD . ARG A 1 283 ? -8.949 1.805 43.018 1.00 18.52 ? 283 ARG A CD 1 ATOM 2202 N NE . ARG A 1 283 ? -8.214 3.004 43.393 1.00 20.61 ? 283 ARG A NE 1 ATOM 2203 C CZ . ARG A 1 283 ? -7.796 3.302 44.618 1.00 23.26 ? 283 ARG A CZ 1 ATOM 2204 N NH1 . ARG A 1 283 ? -8.035 2.500 45.638 1.00 24.76 ? 283 ARG A NH1 1 ATOM 2205 N NH2 . ARG A 1 283 ? -7.136 4.425 44.826 1.00 25.32 ? 283 ARG A NH2 1 ATOM 2206 N N . PRO A 1 284 ? -6.581 -0.745 38.682 1.00 18.52 ? 284 PRO A N 1 ATOM 2207 C CA . PRO A 1 284 ? -6.217 -0.772 37.261 1.00 18.23 ? 284 PRO A CA 1 ATOM 2208 C C . PRO A 1 284 ? -6.052 0.613 36.667 1.00 18.71 ? 284 PRO A C 1 ATOM 2209 O O . PRO A 1 284 ? -6.743 1.564 37.090 1.00 18.73 ? 284 PRO A O 1 ATOM 2210 C CB . PRO A 1 284 ? -7.413 -1.453 36.601 1.00 18.67 ? 284 PRO A CB 1 ATOM 2211 C CG . PRO A 1 284 ? -8.535 -1.363 37.609 1.00 17.83 ? 284 PRO A CG 1 ATOM 2212 C CD . PRO A 1 284 ? -7.887 -1.385 38.938 1.00 17.94 ? 284 PRO A CD 1 ATOM 2213 N N . ALA A 1 285 ? -5.130 0.723 35.703 1.00 18.12 ? 285 ALA A N 1 ATOM 2214 C CA . ALA A 1 285 ? -4.932 1.936 34.934 1.00 17.58 ? 285 ALA A CA 1 ATOM 2215 C C . ALA A 1 285 ? -6.232 2.289 34.232 1.00 17.27 ? 285 ALA A C 1 ATOM 2216 O O . ALA A 1 285 ? -6.953 1.389 33.796 1.00 17.62 ? 285 ALA A O 1 ATOM 2217 C CB . ALA A 1 285 ? -3.871 1.700 33.899 1.00 17.73 ? 285 ALA A CB 1 ATOM 2218 N N . LEU A 1 286 ? -6.524 3.575 34.094 1.00 16.52 ? 286 LEU A N 1 ATOM 2219 C CA . LEU A 1 286 ? -7.638 3.980 33.228 1.00 16.61 ? 286 LEU A CA 1 ATOM 2220 C C . LEU A 1 286 ? -7.112 3.785 31.810 1.00 16.11 ? 286 LEU A C 1 ATOM 2221 O O . LEU A 1 286 ? -6.049 4.294 31.483 1.00 16.32 ? 286 LEU A O 1 ATOM 2222 C CB . LEU A 1 286 ? -8.018 5.447 33.487 1.00 16.65 ? 286 LEU A CB 1 ATOM 2223 C CG . LEU A 1 286 ? -9.194 6.072 32.709 1.00 17.13 ? 286 LEU A CG 1 ATOM 2224 C CD1 . LEU A 1 286 ? -10.547 5.431 33.084 1.00 18.91 ? 286 LEU A CD1 1 ATOM 2225 C CD2 . LEU A 1 286 ? -9.227 7.562 33.026 1.00 16.58 ? 286 LEU A CD2 1 ATOM 2226 N N . PRO A 1 287 ? -7.817 3.015 30.971 1.00 16.33 ? 287 PRO A N 1 ATOM 2227 C CA . PRO A 1 287 ? -7.205 2.844 29.651 1.00 16.29 ? 287 PRO A CA 1 ATOM 2228 C C . PRO A 1 287 ? -7.399 4.061 28.743 1.00 16.16 ? 287 PRO A C 1 ATOM 2229 O O . PRO A 1 287 ? -8.199 4.972 29.049 1.00 16.36 ? 287 PRO A O 1 ATOM 2230 C CB . PRO A 1 287 ? -7.942 1.649 29.079 1.00 16.84 ? 287 PRO A CB 1 ATOM 2231 C CG . PRO A 1 287 ? -9.320 1.740 29.694 1.00 16.41 ? 287 PRO A CG 1 ATOM 2232 C CD . PRO A 1 287 ? -9.108 2.313 31.085 1.00 16.11 ? 287 PRO A CD 1 ATOM 2233 N N . SER A 1 288 ? -6.661 4.076 27.639 1.00 15.32 ? 288 SER A N 1 ATOM 2234 C CA . SER A 1 288 ? -6.904 5.025 26.587 1.00 15.04 ? 288 SER A CA 1 ATOM 2235 C C . SER A 1 288 ? -8.335 4.714 26.088 1.00 15.62 ? 288 SER A C 1 ATOM 2236 O O . SER A 1 288 ? -8.783 3.561 26.075 1.00 14.35 ? 288 SER A O 1 ATOM 2237 C CB . SER A 1 288 ? -5.884 4.876 25.470 1.00 15.34 ? 288 SER A CB 1 ATOM 2238 O OG . SER A 1 288 ? -4.552 5.239 25.884 1.00 14.23 ? 288 SER A OG 1 ATOM 2239 N N . TYR A 1 289 ? -9.075 5.741 25.710 1.00 15.52 ? 289 TYR A N 1 ATOM 2240 C CA . TYR A 1 289 ? -10.445 5.481 25.288 1.00 15.84 ? 289 TYR A CA 1 ATOM 2241 C C . TYR A 1 289 ? -10.463 4.625 23.999 1.00 15.26 ? 289 TYR A C 1 ATOM 2242 O O . TYR A 1 289 ? -11.362 3.802 23.796 1.00 14.45 ? 289 TYR A O 1 ATOM 2243 C CB . TYR A 1 289 ? -11.139 6.812 25.107 1.00 16.31 ? 289 TYR A CB 1 ATOM 2244 C CG . TYR A 1 289 ? -12.626 6.765 24.940 1.00 15.94 ? 289 TYR A CG 1 ATOM 2245 C CD1 . TYR A 1 289 ? -13.457 7.077 25.990 1.00 16.50 ? 289 TYR A CD1 1 ATOM 2246 C CD2 . TYR A 1 289 ? -13.202 6.490 23.711 1.00 18.66 ? 289 TYR A CD2 1 ATOM 2247 C CE1 . TYR A 1 289 ? -14.867 7.117 25.822 1.00 13.52 ? 289 TYR A CE1 1 ATOM 2248 C CE2 . TYR A 1 289 ? -14.590 6.534 23.526 1.00 17.64 ? 289 TYR A CE2 1 ATOM 2249 C CZ . TYR A 1 289 ? -15.408 6.840 24.597 1.00 15.54 ? 289 TYR A CZ 1 ATOM 2250 O OH . TYR A 1 289 ? -16.779 6.864 24.428 1.00 18.00 ? 289 TYR A OH 1 ATOM 2251 N N . TRP A 1 290 ? -9.459 4.783 23.132 1.00 15.15 ? 290 TRP A N 1 ATOM 2252 C CA . TRP A 1 290 ? -9.382 3.941 21.903 1.00 15.35 ? 290 TRP A CA 1 ATOM 2253 C C . TRP A 1 290 ? -9.167 2.435 22.129 1.00 15.54 ? 290 TRP A C 1 ATOM 2254 O O . TRP A 1 290 ? -9.590 1.603 21.308 1.00 15.49 ? 290 TRP A O 1 ATOM 2255 C CB . TRP A 1 290 ? -8.346 4.469 20.932 1.00 16.40 ? 290 TRP A CB 1 ATOM 2256 C CG . TRP A 1 290 ? -6.941 4.569 21.447 1.00 15.29 ? 290 TRP A CG 1 ATOM 2257 C CD1 . TRP A 1 290 ? -6.334 5.674 21.926 1.00 15.88 ? 290 TRP A CD1 1 ATOM 2258 C CD2 . TRP A 1 290 ? -5.956 3.519 21.468 1.00 15.36 ? 290 TRP A CD2 1 ATOM 2259 N NE1 . TRP A 1 290 ? -5.007 5.396 22.232 1.00 16.60 ? 290 TRP A NE1 1 ATOM 2260 C CE2 . TRP A 1 290 ? -4.756 4.079 21.963 1.00 17.19 ? 290 TRP A CE2 1 ATOM 2261 C CE3 . TRP A 1 290 ? -5.974 2.163 21.115 1.00 13.75 ? 290 TRP A CE3 1 ATOM 2262 C CZ2 . TRP A 1 290 ? -3.586 3.323 22.135 1.00 15.13 ? 290 TRP A CZ2 1 ATOM 2263 C CZ3 . TRP A 1 290 ? -4.796 1.421 21.254 1.00 16.60 ? 290 TRP A CZ3 1 ATOM 2264 C CH2 . TRP A 1 290 ? -3.630 2.010 21.770 1.00 15.93 ? 290 TRP A CH2 1 ATOM 2265 N N . ALA A 1 291 ? -8.522 2.080 23.244 1.00 14.63 ? 291 ALA A N 1 ATOM 2266 C CA . ALA A 1 291 ? -8.325 0.656 23.616 1.00 14.25 ? 291 ALA A CA 1 ATOM 2267 C C . ALA A 1 291 ? -9.668 -0.075 23.900 1.00 13.89 ? 291 ALA A C 1 ATOM 2268 O O . ALA A 1 291 ? -9.756 -1.314 23.917 1.00 12.95 ? 291 ALA A O 1 ATOM 2269 C CB . ALA A 1 291 ? -7.428 0.571 24.793 1.00 12.75 ? 291 ALA A CB 1 ATOM 2270 N N . LEU A 1 292 ? -10.709 0.704 24.105 1.00 14.83 ? 292 LEU A N 1 ATOM 2271 C CA . LEU A 1 292 ? -12.049 0.158 24.384 1.00 15.81 ? 292 LEU A CA 1 ATOM 2272 C C . LEU A 1 292 ? -12.678 -0.266 23.096 1.00 15.95 ? 292 LEU A C 1 ATOM 2273 O O . LEU A 1 292 ? -13.685 -0.974 23.090 1.00 17.23 ? 292 LEU A O 1 ATOM 2274 C CB . LEU A 1 292 ? -12.949 1.203 25.060 1.00 16.51 ? 292 LEU A CB 1 ATOM 2275 C CG . LEU A 1 292 ? -12.521 1.808 26.402 1.00 20.45 ? 292 LEU A CG 1 ATOM 2276 C CD1 . LEU A 1 292 ? -13.596 2.806 26.889 1.00 21.77 ? 292 LEU A CD1 1 ATOM 2277 C CD2 . LEU A 1 292 ? -12.337 0.745 27.402 1.00 21.53 ? 292 LEU A CD2 1 ATOM 2278 N N . GLY A 1 293 ? -12.111 0.205 21.991 1.00 16.24 ? 293 GLY A N 1 ATOM 2279 C CA . GLY A 1 293 ? -12.544 -0.209 20.665 1.00 14.88 ? 293 GLY A CA 1 ATOM 2280 C C . GLY A 1 293 ? -12.243 -1.641 20.301 1.00 15.02 ? 293 GLY A C 1 ATOM 2281 O O . GLY A 1 293 ? -11.699 -2.441 21.108 1.00 14.08 ? 293 GLY A O 1 ATOM 2282 N N . PHE A 1 294 ? -12.626 -1.989 19.076 1.00 14.50 ? 294 PHE A N 1 ATOM 2283 C CA . PHE A 1 294 ? -12.470 -3.335 18.608 1.00 13.93 ? 294 PHE A CA 1 ATOM 2284 C C . PHE A 1 294 ? -11.068 -3.444 18.043 1.00 14.65 ? 294 PHE A C 1 ATOM 2285 O O . PHE A 1 294 ? -10.620 -2.539 17.344 1.00 14.41 ? 294 PHE A O 1 ATOM 2286 C CB . PHE A 1 294 ? -13.499 -3.649 17.547 1.00 14.10 ? 294 PHE A CB 1 ATOM 2287 C CG . PHE A 1 294 ? -13.354 -5.011 16.946 1.00 15.20 ? 294 PHE A CG 1 ATOM 2288 C CD1 . PHE A 1 294 ? -13.546 -6.150 17.721 1.00 15.07 ? 294 PHE A CD1 1 ATOM 2289 C CD2 . PHE A 1 294 ? -13.026 -5.151 15.600 1.00 17.35 ? 294 PHE A CD2 1 ATOM 2290 C CE1 . PHE A 1 294 ? -13.400 -7.412 17.168 1.00 17.29 ? 294 PHE A CE1 1 ATOM 2291 C CE2 . PHE A 1 294 ? -12.896 -6.408 15.023 1.00 19.37 ? 294 PHE A CE2 1 ATOM 2292 C CZ . PHE A 1 294 ? -13.093 -7.549 15.813 1.00 17.67 ? 294 PHE A CZ 1 ATOM 2293 N N . HIS A 1 295 ? -10.372 -4.526 18.385 1.00 14.44 ? 295 HIS A N 1 ATOM 2294 C CA . HIS A 1 295 ? -8.966 -4.731 17.950 1.00 13.47 ? 295 HIS A CA 1 ATOM 2295 C C . HIS A 1 295 ? -8.952 -5.904 16.934 1.00 14.26 ? 295 HIS A C 1 ATOM 2296 O O . HIS A 1 295 ? -9.653 -6.892 17.107 1.00 13.41 ? 295 HIS A O 1 ATOM 2297 C CB . HIS A 1 295 ? -8.106 -5.145 19.159 1.00 13.71 ? 295 HIS A CB 1 ATOM 2298 C CG . HIS A 1 295 ? -7.914 -4.093 20.214 1.00 12.85 ? 295 HIS A CG 1 ATOM 2299 N ND1 . HIS A 1 295 ? -8.953 -3.568 20.963 1.00 15.28 ? 295 HIS A ND1 1 ATOM 2300 C CD2 . HIS A 1 295 ? -6.786 -3.536 20.705 1.00 9.39 ? 295 HIS A CD2 1 ATOM 2301 C CE1 . HIS A 1 295 ? -8.472 -2.699 21.836 1.00 12.20 ? 295 HIS A CE1 1 ATOM 2302 N NE2 . HIS A 1 295 ? -7.155 -2.667 21.704 1.00 15.79 ? 295 HIS A NE2 1 ATOM 2303 N N . LEU A 1 296 ? -8.150 -5.817 15.886 1.00 15.44 ? 296 LEU A N 1 ATOM 2304 C CA . LEU A 1 296 ? -8.063 -6.885 14.892 1.00 16.16 ? 296 LEU A CA 1 ATOM 2305 C C . LEU A 1 296 ? -6.608 -7.348 14.798 1.00 17.43 ? 296 LEU A C 1 ATOM 2306 O O . LEU A 1 296 ? -5.674 -6.555 14.842 1.00 17.70 ? 296 LEU A O 1 ATOM 2307 C CB . LEU A 1 296 ? -8.600 -6.416 13.511 1.00 16.52 ? 296 LEU A CB 1 ATOM 2308 C CG . LEU A 1 296 ? -8.876 -7.516 12.457 1.00 18.19 ? 296 LEU A CG 1 ATOM 2309 C CD1 . LEU A 1 296 ? -9.828 -8.576 13.012 1.00 13.19 ? 296 LEU A CD1 1 ATOM 2310 C CD2 . LEU A 1 296 ? -9.393 -6.978 11.140 1.00 15.99 ? 296 LEU A CD2 1 ATOM 2311 N N . SER A 1 297 ? -6.410 -8.644 14.640 1.00 19.40 ? 297 SER A N 1 ATOM 2312 C CA . SER A 1 297 ? -5.062 -9.200 14.693 1.00 20.30 ? 297 SER A CA 1 ATOM 2313 C C . SER A 1 297 ? -5.037 -10.551 13.999 1.00 20.06 ? 297 SER A C 1 ATOM 2314 O O . SER A 1 297 ? -6.087 -11.199 13.834 1.00 20.01 ? 297 SER A O 1 ATOM 2315 C CB . SER A 1 297 ? -4.679 -9.399 16.173 1.00 20.45 ? 297 SER A CB 1 ATOM 2316 O OG . SER A 1 297 ? -3.327 -9.838 16.347 1.00 24.23 ? 297 SER A OG 1 ATOM 2317 N N . ARG A 1 298 ? -3.829 -10.994 13.647 1.00 19.58 ? 298 ARG A N 1 ATOM 2318 C CA . ARG A 1 298 ? -3.576 -12.408 13.394 1.00 19.56 ? 298 ARG A CA 1 ATOM 2319 C C . ARG A 1 298 ? -2.086 -12.697 13.409 1.00 19.78 ? 298 ARG A C 1 ATOM 2320 O O . ARG A 1 298 ? -1.245 -11.807 13.231 1.00 19.70 ? 298 ARG A O 1 ATOM 2321 C CB . ARG A 1 298 ? -4.234 -12.942 12.104 1.00 19.56 ? 298 ARG A CB 1 ATOM 2322 C CG . ARG A 1 298 ? -3.379 -12.813 10.866 1.00 20.74 ? 298 ARG A CG 1 ATOM 2323 C CD . ARG A 1 298 ? -3.762 -13.729 9.748 1.00 21.16 ? 298 ARG A CD 1 ATOM 2324 N NE . ARG A 1 298 ? -3.482 -15.139 10.009 1.00 21.55 ? 298 ARG A NE 1 ATOM 2325 C CZ . ARG A 1 298 ? -4.220 -16.123 9.514 1.00 21.52 ? 298 ARG A CZ 1 ATOM 2326 N NH1 . ARG A 1 298 ? -5.271 -15.840 8.760 1.00 20.44 ? 298 ARG A NH1 1 ATOM 2327 N NH2 . ARG A 1 298 ? -3.936 -17.387 9.788 1.00 22.90 ? 298 ARG A NH2 1 ATOM 2328 N N . TYR A 1 299 ? -1.779 -13.948 13.692 1.00 20.15 ? 299 TYR A N 1 ATOM 2329 C CA . TYR A 1 299 ? -0.428 -14.455 13.619 1.00 21.20 ? 299 TYR A CA 1 ATOM 2330 C C . TYR A 1 299 ? -0.166 -14.767 12.139 1.00 21.38 ? 299 TYR A C 1 ATOM 2331 O O . TYR A 1 299 ? -0.881 -15.540 11.523 1.00 21.26 ? 299 TYR A O 1 ATOM 2332 C CB . TYR A 1 299 ? -0.339 -15.681 14.545 1.00 21.82 ? 299 TYR A CB 1 ATOM 2333 C CG . TYR A 1 299 ? 1.031 -16.303 14.739 1.00 21.43 ? 299 TYR A CG 1 ATOM 2334 C CD1 . TYR A 1 299 ? 1.158 -17.524 15.395 1.00 21.39 ? 299 TYR A CD1 1 ATOM 2335 C CD2 . TYR A 1 299 ? 2.186 -15.698 14.246 1.00 21.85 ? 299 TYR A CD2 1 ATOM 2336 C CE1 . TYR A 1 299 ? 2.421 -18.134 15.575 1.00 21.64 ? 299 TYR A CE1 1 ATOM 2337 C CE2 . TYR A 1 299 ? 3.436 -16.294 14.416 1.00 22.66 ? 299 TYR A CE2 1 ATOM 2338 C CZ . TYR A 1 299 ? 3.544 -17.507 15.069 1.00 22.02 ? 299 TYR A CZ 1 ATOM 2339 O OH . TYR A 1 299 ? 4.791 -18.069 15.228 1.00 23.70 ? 299 TYR A OH 1 ATOM 2340 N N . GLU A 1 300 ? 0.811 -14.086 11.549 1.00 21.74 ? 300 GLU A N 1 ATOM 2341 C CA . GLU A 1 300 ? 1.211 -14.348 10.170 1.00 22.31 ? 300 GLU A CA 1 ATOM 2342 C C . GLU A 1 300 ? 0.208 -13.883 9.099 1.00 21.68 ? 300 GLU A C 1 ATOM 2343 O O . GLU A 1 300 ? -0.437 -14.698 8.430 1.00 21.69 ? 300 GLU A O 1 ATOM 2344 C CB . GLU A 1 300 ? 1.613 -15.817 9.953 1.00 22.58 ? 300 GLU A CB 1 ATOM 2345 C CG . GLU A 1 300 ? 2.820 -16.263 10.755 1.00 26.28 ? 300 GLU A CG 1 ATOM 2346 C CD . GLU A 1 300 ? 4.161 -15.728 10.236 1.00 28.99 ? 300 GLU A CD 1 ATOM 2347 O OE1 . GLU A 1 300 ? 4.288 -15.458 9.015 1.00 31.50 ? 300 GLU A OE1 1 ATOM 2348 O OE2 . GLU A 1 300 ? 5.092 -15.590 11.075 1.00 31.23 ? 300 GLU A OE2 1 ATOM 2349 N N . TYR A 1 301 ? 0.081 -12.573 8.949 1.00 21.82 ? 301 TYR A N 1 ATOM 2350 C CA . TYR A 1 301 ? -0.404 -12.015 7.696 1.00 21.03 ? 301 TYR A CA 1 ATOM 2351 C C . TYR A 1 301 ? 0.644 -12.354 6.647 1.00 21.63 ? 301 TYR A C 1 ATOM 2352 O O . TYR A 1 301 ? 0.315 -12.670 5.508 1.00 21.25 ? 301 TYR A O 1 ATOM 2353 C CB . TYR A 1 301 ? -0.590 -10.510 7.815 1.00 20.71 ? 301 TYR A CB 1 ATOM 2354 C CG . TYR A 1 301 ? -1.763 -10.103 8.684 1.00 20.93 ? 301 TYR A CG 1 ATOM 2355 C CD1 . TYR A 1 301 ? -3.078 -10.276 8.230 1.00 20.61 ? 301 TYR A CD1 1 ATOM 2356 C CD2 . TYR A 1 301 ? -1.565 -9.528 9.947 1.00 20.44 ? 301 TYR A CD2 1 ATOM 2357 C CE1 . TYR A 1 301 ? -4.164 -9.892 9.008 1.00 20.78 ? 301 TYR A CE1 1 ATOM 2358 C CE2 . TYR A 1 301 ? -2.669 -9.130 10.745 1.00 20.36 ? 301 TYR A CE2 1 ATOM 2359 C CZ . TYR A 1 301 ? -3.957 -9.326 10.263 1.00 19.47 ? 301 TYR A CZ 1 ATOM 2360 O OH . TYR A 1 301 ? -5.062 -8.968 11.016 1.00 19.99 ? 301 TYR A OH 1 ATOM 2361 N N . GLY A 1 302 ? 1.913 -12.318 7.057 1.00 22.36 ? 302 GLY A N 1 ATOM 2362 C CA . GLY A 1 302 ? 3.002 -12.841 6.237 1.00 23.12 ? 302 GLY A CA 1 ATOM 2363 C C . GLY A 1 302 ? 3.679 -11.702 5.518 1.00 23.66 ? 302 GLY A C 1 ATOM 2364 O O . GLY A 1 302 ? 4.912 -11.612 5.470 1.00 24.18 ? 302 GLY A O 1 ATOM 2365 N N . THR A 1 303 ? 2.853 -10.840 4.942 1.00 23.68 ? 303 THR A N 1 ATOM 2366 C CA . THR A 1 303 ? 3.298 -9.626 4.270 1.00 24.15 ? 303 THR A CA 1 ATOM 2367 C C . THR A 1 303 ? 2.404 -8.453 4.672 1.00 24.53 ? 303 THR A C 1 ATOM 2368 O O . THR A 1 303 ? 1.229 -8.642 5.064 1.00 23.26 ? 303 THR A O 1 ATOM 2369 C CB . THR A 1 303 ? 3.254 -9.737 2.712 1.00 24.30 ? 303 THR A CB 1 ATOM 2370 O OG1 . THR A 1 303 ? 1.901 -9.886 2.277 1.00 25.02 ? 303 THR A OG1 1 ATOM 2371 C CG2 . THR A 1 303 ? 4.063 -10.914 2.201 1.00 23.21 ? 303 THR A CG2 1 ATOM 2372 N N . LEU A 1 304 ? 2.974 -7.252 4.569 1.00 24.46 ? 304 LEU A N 1 ATOM 2373 C CA . LEU A 1 304 ? 2.226 -6.019 4.765 1.00 25.04 ? 304 LEU A CA 1 ATOM 2374 C C . LEU A 1 304 ? 1.037 -5.892 3.827 1.00 25.14 ? 304 LEU A C 1 ATOM 2375 O O . LEU A 1 304 ? -0.021 -5.444 4.255 1.00 25.71 ? 304 LEU A O 1 ATOM 2376 C CB . LEU A 1 304 ? 3.121 -4.795 4.634 1.00 24.40 ? 304 LEU A CB 1 ATOM 2377 C CG . LEU A 1 304 ? 2.465 -3.462 5.005 1.00 23.96 ? 304 LEU A CG 1 ATOM 2378 C CD1 . LEU A 1 304 ? 1.851 -3.520 6.417 1.00 23.57 ? 304 LEU A CD1 1 ATOM 2379 C CD2 . LEU A 1 304 ? 3.458 -2.321 4.919 1.00 25.22 ? 304 LEU A CD2 1 ATOM 2380 N N . ASP A 1 305 ? 1.217 -6.284 2.562 1.00 25.86 ? 305 ASP A N 1 ATOM 2381 C CA . ASP A 1 305 ? 0.145 -6.306 1.565 1.00 25.79 ? 305 ASP A CA 1 ATOM 2382 C C . ASP A 1 305 ? -1.042 -7.172 2.016 1.00 25.35 ? 305 ASP A C 1 ATOM 2383 O O . ASP A 1 305 ? -2.204 -6.865 1.713 1.00 24.14 ? 305 ASP A O 1 ATOM 2384 C CB . ASP A 1 305 ? 0.666 -6.851 0.241 1.00 27.17 ? 305 ASP A CB 1 ATOM 2385 C CG . ASP A 1 305 ? 1.655 -5.900 -0.473 1.00 30.36 ? 305 ASP A CG 1 ATOM 2386 O OD1 . ASP A 1 305 ? 1.935 -4.776 0.007 1.00 33.88 ? 305 ASP A OD1 1 ATOM 2387 O OD2 . ASP A 1 305 ? 2.150 -6.295 -1.552 1.00 33.85 ? 305 ASP A OD2 1 ATOM 2388 N N . ASN A 1 306 ? -0.732 -8.278 2.691 1.00 24.75 ? 306 ASN A N 1 ATOM 2389 C CA . ASN A 1 306 ? -1.756 -9.176 3.238 1.00 25.16 ? 306 ASN A CA 1 ATOM 2390 C C . ASN A 1 306 ? -2.509 -8.519 4.397 1.00 25.16 ? 306 ASN A C 1 ATOM 2391 O O . ASN A 1 306 ? -3.758 -8.589 4.454 1.00 25.42 ? 306 ASN A O 1 ATOM 2392 C CB . ASN A 1 306 ? -1.139 -10.515 3.663 1.00 25.27 ? 306 ASN A CB 1 ATOM 2393 C CG . ASN A 1 306 ? -0.897 -11.464 2.479 1.00 26.21 ? 306 ASN A CG 1 ATOM 2394 O OD1 . ASN A 1 306 ? -1.415 -11.263 1.379 1.00 26.76 ? 306 ASN A OD1 1 ATOM 2395 N ND2 . ASN A 1 306 ? -0.092 -12.500 2.709 1.00 28.87 ? 306 ASN A ND2 1 ATOM 2396 N N . MET A 1 307 ? -1.755 -7.870 5.293 1.00 24.68 ? 307 MET A N 1 ATOM 2397 C CA . MET A 1 307 ? -2.317 -7.088 6.409 1.00 25.37 ? 307 MET A CA 1 ATOM 2398 C C . MET A 1 307 ? -3.179 -5.945 5.884 1.00 25.28 ? 307 MET A C 1 ATOM 2399 O O . MET A 1 307 ? -4.330 -5.794 6.317 1.00 25.62 ? 307 MET A O 1 ATOM 2400 C CB . MET A 1 307 ? -1.209 -6.559 7.339 1.00 25.25 ? 307 MET A CB 1 ATOM 2401 C CG . MET A 1 307 ? -1.710 -5.809 8.603 1.00 25.06 ? 307 MET A CG 1 ATOM 2402 S SD . MET A 1 307 ? -0.374 -5.139 9.592 1.00 28.05 ? 307 MET A SD 1 ATOM 2403 C CE . MET A 1 307 ? 0.378 -6.591 10.300 1.00 27.55 ? 307 MET A CE 1 ATOM 2404 N N . ARG A 1 308 ? -2.631 -5.160 4.946 1.00 24.59 ? 308 ARG A N 1 ATOM 2405 C CA . ARG A 1 308 ? -3.342 -4.050 4.313 1.00 24.53 ? 308 ARG A CA 1 ATOM 2406 C C . ARG A 1 308 ? -4.656 -4.515 3.701 1.00 24.02 ? 308 ARG A C 1 ATOM 2407 O O . ARG A 1 308 ? -5.664 -3.836 3.823 1.00 23.40 ? 308 ARG A O 1 ATOM 2408 C CB . ARG A 1 308 ? -2.500 -3.395 3.212 1.00 25.37 ? 308 ARG A CB 1 ATOM 2409 C CG . ARG A 1 308 ? -1.445 -2.390 3.642 1.00 28.35 ? 308 ARG A CG 1 ATOM 2410 C CD . ARG A 1 308 ? -1.159 -1.401 2.476 1.00 34.28 ? 308 ARG A CD 1 ATOM 2411 N NE . ARG A 1 308 ? -0.171 -0.369 2.810 1.00 37.66 ? 308 ARG A NE 1 ATOM 2412 C CZ . ARG A 1 308 ? 1.109 -0.416 2.436 1.00 39.76 ? 308 ARG A CZ 1 ATOM 2413 N NH1 . ARG A 1 308 ? 1.545 -1.438 1.715 1.00 41.20 ? 308 ARG A NH1 1 ATOM 2414 N NH2 . ARG A 1 308 ? 1.953 0.556 2.766 1.00 40.22 ? 308 ARG A NH2 1 ATOM 2415 N N . GLU A 1 309 ? -4.631 -5.660 3.032 1.00 23.57 ? 309 GLU A N 1 ATOM 2416 C CA . GLU A 1 309 ? -5.821 -6.226 2.427 1.00 25.37 ? 309 GLU A CA 1 ATOM 2417 C C . GLU A 1 309 ? -6.921 -6.580 3.450 1.00 23.88 ? 309 GLU A C 1 ATOM 2418 O O . GLU A 1 309 ? -8.116 -6.386 3.189 1.00 23.73 ? 309 GLU A O 1 ATOM 2419 C CB . GLU A 1 309 ? -5.472 -7.458 1.575 1.00 25.44 ? 309 GLU A CB 1 ATOM 2420 C CG . GLU A 1 309 ? -6.706 -7.992 0.827 1.00 28.24 ? 309 GLU A CG 1 ATOM 2421 C CD . GLU A 1 309 ? -6.497 -9.328 0.137 1.00 30.06 ? 309 GLU A CD 1 ATOM 2422 O OE1 . GLU A 1 309 ? -5.329 -9.689 -0.169 1.00 34.92 ? 309 GLU A OE1 1 ATOM 2423 O OE2 . GLU A 1 309 ? -7.529 -10.019 -0.111 1.00 36.38 ? 309 GLU A OE2 1 ATOM 2424 N N . VAL A 1 310 ? -6.517 -7.134 4.589 1.00 22.61 ? 310 VAL A N 1 ATOM 2425 C CA . VAL A 1 310 ? -7.453 -7.415 5.676 1.00 21.77 ? 310 VAL A CA 1 ATOM 2426 C C . VAL A 1 310 ? -8.016 -6.115 6.284 1.00 21.45 ? 310 VAL A C 1 ATOM 2427 O O . VAL A 1 310 ? -9.230 -6.000 6.469 1.00 21.85 ? 310 VAL A O 1 ATOM 2428 C CB . VAL A 1 310 ? -6.815 -8.353 6.760 1.00 22.30 ? 310 VAL A CB 1 ATOM 2429 C CG1 . VAL A 1 310 ? -7.818 -8.625 7.934 1.00 22.12 ? 310 VAL A CG1 1 ATOM 2430 C CG2 . VAL A 1 310 ? -6.359 -9.674 6.105 1.00 21.13 ? 310 VAL A CG2 1 ATOM 2431 N N . VAL A 1 311 ? -7.140 -5.146 6.561 1.00 21.09 ? 311 VAL A N 1 ATOM 2432 C CA . VAL A 1 311 ? -7.512 -3.839 7.102 1.00 22.23 ? 311 VAL A CA 1 ATOM 2433 C C . VAL A 1 311 ? -8.589 -3.200 6.215 1.00 22.96 ? 311 VAL A C 1 ATOM 2434 O O . VAL A 1 311 ? -9.634 -2.785 6.702 1.00 23.06 ? 311 VAL A O 1 ATOM 2435 C CB . VAL A 1 311 ? -6.280 -2.873 7.248 1.00 22.31 ? 311 VAL A CB 1 ATOM 2436 C CG1 . VAL A 1 311 ? -6.727 -1.437 7.631 1.00 22.43 ? 311 VAL A CG1 1 ATOM 2437 C CG2 . VAL A 1 311 ? -5.278 -3.394 8.266 1.00 20.93 ? 311 VAL A CG2 1 ATOM 2438 N N . GLU A 1 312 ? -8.348 -3.192 4.905 1.00 23.03 ? 312 GLU A N 1 ATOM 2439 C CA . GLU A 1 312 ? -9.193 -2.459 3.986 1.00 23.74 ? 312 GLU A CA 1 ATOM 2440 C C . GLU A 1 312 ? -10.545 -3.129 3.718 1.00 22.75 ? 312 GLU A C 1 ATOM 2441 O O . GLU A 1 312 ? -11.525 -2.428 3.577 1.00 22.94 ? 312 GLU A O 1 ATOM 2442 C CB . GLU A 1 312 ? -8.430 -2.090 2.708 1.00 24.98 ? 312 GLU A CB 1 ATOM 2443 C CG . GLU A 1 312 ? -7.393 -0.957 2.936 1.00 29.80 ? 312 GLU A CG 1 ATOM 2444 C CD . GLU A 1 312 ? -7.964 0.322 3.606 1.00 36.79 ? 312 GLU A CD 1 ATOM 2445 O OE1 . GLU A 1 312 ? -8.987 0.859 3.100 1.00 39.66 ? 312 GLU A OE1 1 ATOM 2446 O OE2 . GLU A 1 312 ? -7.367 0.805 4.619 1.00 37.30 ? 312 GLU A OE2 1 ATOM 2447 N N . ARG A 1 313 ? -10.614 -4.460 3.697 1.00 21.93 ? 313 ARG A N 1 ATOM 2448 C CA . ARG A 1 313 ? -11.927 -5.118 3.597 1.00 21.96 ? 313 ARG A CA 1 ATOM 2449 C C . ARG A 1 313 ? -12.790 -4.887 4.860 1.00 21.23 ? 313 ARG A C 1 ATOM 2450 O O . ARG A 1 313 ? -13.996 -4.752 4.758 1.00 21.28 ? 313 ARG A O 1 ATOM 2451 C CB . ARG A 1 313 ? -11.850 -6.613 3.184 1.00 21.77 ? 313 ARG A CB 1 ATOM 2452 C CG . ARG A 1 313 ? -11.214 -7.587 4.194 1.00 21.93 ? 313 ARG A CG 1 ATOM 2453 C CD . ARG A 1 313 ? -11.535 -9.029 3.841 1.00 22.38 ? 313 ARG A CD 1 ATOM 2454 N NE . ARG A 1 313 ? -10.820 -9.968 4.701 1.00 26.16 ? 313 ARG A NE 1 ATOM 2455 C CZ . ARG A 1 313 ? -9.986 -10.914 4.274 1.00 25.90 ? 313 ARG A CZ 1 ATOM 2456 N NH1 . ARG A 1 313 ? -9.745 -11.077 2.979 1.00 28.63 ? 313 ARG A NH1 1 ATOM 2457 N NH2 . ARG A 1 313 ? -9.395 -11.708 5.146 1.00 25.75 ? 313 ARG A NH2 1 ATOM 2458 N N . ASN A 1 314 ? -12.171 -4.807 6.031 1.00 20.38 ? 314 ASN A N 1 ATOM 2459 C CA . ASN A 1 314 ? -12.936 -4.526 7.252 1.00 20.89 ? 314 ASN A CA 1 ATOM 2460 C C . ASN A 1 314 ? -13.383 -3.075 7.362 1.00 20.69 ? 314 ASN A C 1 ATOM 2461 O O . ASN A 1 314 ? -14.521 -2.800 7.730 1.00 20.45 ? 314 ASN A O 1 ATOM 2462 C CB . ASN A 1 314 ? -12.214 -5.042 8.502 1.00 20.41 ? 314 ASN A CB 1 ATOM 2463 C CG . ASN A 1 314 ? -12.270 -6.545 8.597 1.00 21.29 ? 314 ASN A CG 1 ATOM 2464 O OD1 . ASN A 1 314 ? -13.265 -7.105 9.047 1.00 24.92 ? 314 ASN A OD1 1 ATOM 2465 N ND2 . ASN A 1 314 ? -11.224 -7.217 8.130 1.00 21.74 ? 314 ASN A ND2 1 ATOM 2466 N N . ARG A 1 315 ? -12.487 -2.166 6.999 1.00 20.77 ? 315 ARG A N 1 ATOM 2467 C CA . ARG A 1 315 ? -12.807 -0.759 6.812 1.00 21.67 ? 315 ARG A CA 1 ATOM 2468 C C . ARG A 1 315 ? -13.852 -0.524 5.729 1.00 22.15 ? 315 ARG A C 1 ATOM 2469 O O . ARG A 1 315 ? -14.741 0.319 5.907 1.00 22.02 ? 315 ARG A O 1 ATOM 2470 C CB . ARG A 1 315 ? -11.548 0.031 6.487 1.00 21.93 ? 315 ARG A CB 1 ATOM 2471 C CG . ARG A 1 315 ? -10.791 0.422 7.703 1.00 21.00 ? 315 ARG A CG 1 ATOM 2472 C CD . ARG A 1 315 ? -9.667 1.350 7.337 1.00 21.92 ? 315 ARG A CD 1 ATOM 2473 N NE . ARG A 1 315 ? -10.087 2.736 7.342 1.00 22.45 ? 315 ARG A NE 1 ATOM 2474 C CZ . ARG A 1 315 ? -10.382 3.457 6.262 1.00 27.94 ? 315 ARG A CZ 1 ATOM 2475 N NH1 . ARG A 1 315 ? -10.332 2.932 5.031 1.00 26.63 ? 315 ARG A NH1 1 ATOM 2476 N NH2 . ARG A 1 315 ? -10.733 4.724 6.418 1.00 29.52 ? 315 ARG A NH2 1 ATOM 2477 N N . ALA A 1 316 ? -13.761 -1.274 4.624 1.00 22.76 ? 316 ALA A N 1 ATOM 2478 C CA . ALA A 1 316 ? -14.748 -1.176 3.557 1.00 23.30 ? 316 ALA A CA 1 ATOM 2479 C C . ALA A 1 316 ? -16.127 -1.644 4.038 1.00 23.73 ? 316 ALA A C 1 ATOM 2480 O O . ALA A 1 316 ? -17.152 -1.168 3.550 1.00 24.35 ? 316 ALA A O 1 ATOM 2481 C CB . ALA A 1 316 ? -14.311 -1.982 2.311 1.00 23.48 ? 316 ALA A CB 1 ATOM 2482 N N . ALA A 1 317 ? -16.145 -2.557 5.012 1.00 23.49 ? 317 ALA A N 1 ATOM 2483 C CA . ALA A 1 317 ? -17.393 -3.074 5.569 1.00 23.93 ? 317 ALA A CA 1 ATOM 2484 C C . ALA A 1 317 ? -18.050 -2.178 6.639 1.00 23.78 ? 317 ALA A C 1 ATOM 2485 O O . ALA A 1 317 ? -19.119 -2.522 7.155 1.00 24.48 ? 317 ALA A O 1 ATOM 2486 C CB . ALA A 1 317 ? -17.170 -4.468 6.118 1.00 23.80 ? 317 ALA A CB 1 ATOM 2487 N N . GLN A 1 318 ? -17.414 -1.049 6.945 1.00 23.14 ? 318 GLN A N 1 ATOM 2488 C CA . GLN A 1 318 ? -17.856 -0.089 7.961 1.00 24.19 ? 318 GLN A CA 1 ATOM 2489 C C . GLN A 1 318 ? -17.880 -0.731 9.354 1.00 24.10 ? 318 GLN A C 1 ATOM 2490 O O . GLN A 1 318 ? -18.815 -0.525 10.144 1.00 24.64 ? 318 GLN A O 1 ATOM 2491 C CB . GLN A 1 318 ? -19.208 0.580 7.591 1.00 24.98 ? 318 GLN A CB 1 ATOM 2492 C CG . GLN A 1 318 ? -19.214 1.342 6.228 1.00 26.73 ? 318 GLN A CG 1 ATOM 2493 C CD . GLN A 1 318 ? -18.060 2.353 6.101 1.00 28.56 ? 318 GLN A CD 1 ATOM 2494 O OE1 . GLN A 1 318 ? -17.842 3.181 6.981 1.00 30.70 ? 318 GLN A OE1 1 ATOM 2495 N NE2 . GLN A 1 318 ? -17.334 2.287 4.999 1.00 30.65 ? 318 GLN A NE2 1 ATOM 2496 N N . LEU A 1 319 ? -16.848 -1.534 9.625 1.00 23.24 ? 319 LEU A N 1 ATOM 2497 C CA . LEU A 1 319 ? -16.708 -2.231 10.902 1.00 22.31 ? 319 LEU A CA 1 ATOM 2498 C C . LEU A 1 319 ? -16.138 -1.267 11.910 1.00 21.57 ? 319 LEU A C 1 ATOM 2499 O O . LEU A 1 319 ? -15.154 -0.584 11.615 1.00 22.63 ? 319 LEU A O 1 ATOM 2500 C CB . LEU A 1 319 ? -15.794 -3.458 10.771 1.00 22.02 ? 319 LEU A CB 1 ATOM 2501 C CG . LEU A 1 319 ? -15.807 -4.450 11.950 1.00 22.29 ? 319 LEU A CG 1 ATOM 2502 C CD1 . LEU A 1 319 ? -17.079 -5.291 11.996 1.00 19.91 ? 319 LEU A CD1 1 ATOM 2503 C CD2 . LEU A 1 319 ? -14.566 -5.357 11.954 1.00 20.80 ? 319 LEU A CD2 1 ATOM 2504 N N . PRO A 1 320 ? -16.773 -1.162 13.095 1.00 21.22 ? 320 PRO A N 1 ATOM 2505 C CA . PRO A 1 320 ? -16.138 -0.396 14.131 1.00 19.88 ? 320 PRO A CA 1 ATOM 2506 C C . PRO A 1 320 ? -14.860 -1.151 14.442 1.00 18.51 ? 320 PRO A C 1 ATOM 2507 O O . PRO A 1 320 ? -14.888 -2.360 14.644 1.00 17.60 ? 320 PRO A O 1 ATOM 2508 C CB . PRO A 1 320 ? -17.136 -0.495 15.283 1.00 19.89 ? 320 PRO A CB 1 ATOM 2509 C CG . PRO A 1 320 ? -18.429 -0.744 14.630 1.00 20.48 ? 320 PRO A CG 1 ATOM 2510 C CD . PRO A 1 320 ? -18.055 -1.718 13.571 1.00 20.69 ? 320 PRO A CD 1 ATOM 2511 N N . TYR A 1 321 ? -13.748 -0.435 14.461 1.00 17.76 ? 321 TYR A N 1 ATOM 2512 C CA . TYR A 1 321 ? -12.453 -1.079 14.322 1.00 17.79 ? 321 TYR A CA 1 ATOM 2513 C C . TYR A 1 321 ? -11.444 0.000 14.631 1.00 17.08 ? 321 TYR A C 1 ATOM 2514 O O . TYR A 1 321 ? -11.187 0.834 13.807 1.00 17.96 ? 321 TYR A O 1 ATOM 2515 C CB . TYR A 1 321 ? -12.379 -1.574 12.862 1.00 18.43 ? 321 TYR A CB 1 ATOM 2516 C CG . TYR A 1 321 ? -11.060 -2.089 12.299 1.00 18.79 ? 321 TYR A CG 1 ATOM 2517 C CD1 . TYR A 1 321 ? -9.984 -2.464 13.127 1.00 18.89 ? 321 TYR A CD1 1 ATOM 2518 C CD2 . TYR A 1 321 ? -10.930 -2.261 10.928 1.00 16.30 ? 321 TYR A CD2 1 ATOM 2519 C CE1 . TYR A 1 321 ? -8.785 -2.954 12.573 1.00 17.88 ? 321 TYR A CE1 1 ATOM 2520 C CE2 . TYR A 1 321 ? -9.769 -2.756 10.372 1.00 20.53 ? 321 TYR A CE2 1 ATOM 2521 C CZ . TYR A 1 321 ? -8.699 -3.099 11.193 1.00 19.96 ? 321 TYR A CZ 1 ATOM 2522 O OH . TYR A 1 321 ? -7.559 -3.576 10.614 1.00 19.12 ? 321 TYR A OH 1 ATOM 2523 N N . ASP A 1 322 ? -10.905 0.010 15.843 1.00 17.04 ? 322 ASP A N 1 ATOM 2524 C CA . ASP A 1 322 ? -9.986 1.046 16.269 1.00 17.90 ? 322 ASP A CA 1 ATOM 2525 C C . ASP A 1 322 ? -8.531 0.659 16.166 1.00 18.14 ? 322 ASP A C 1 ATOM 2526 O O . ASP A 1 322 ? -7.695 1.528 15.964 1.00 18.67 ? 322 ASP A O 1 ATOM 2527 C CB . ASP A 1 322 ? -10.247 1.450 17.719 1.00 17.72 ? 322 ASP A CB 1 ATOM 2528 C CG . ASP A 1 322 ? -11.204 2.577 17.824 1.00 20.59 ? 322 ASP A CG 1 ATOM 2529 O OD1 . ASP A 1 322 ? -10.731 3.707 18.090 1.00 19.75 ? 322 ASP A OD1 1 ATOM 2530 O OD2 . ASP A 1 322 ? -12.420 2.315 17.605 1.00 18.24 ? 322 ASP A OD2 1 ATOM 2531 N N . VAL A 1 323 ? -8.226 -0.622 16.369 1.00 18.29 ? 323 VAL A N 1 ATOM 2532 C CA . VAL A 1 323 ? -6.834 -1.035 16.588 1.00 18.43 ? 323 VAL A CA 1 ATOM 2533 C C . VAL A 1 323 ? -6.448 -2.200 15.674 1.00 18.31 ? 323 VAL A C 1 ATOM 2534 O O . VAL A 1 323 ? -7.204 -3.142 15.505 1.00 18.35 ? 323 VAL A O 1 ATOM 2535 C CB . VAL A 1 323 ? -6.568 -1.395 18.084 1.00 18.07 ? 323 VAL A CB 1 ATOM 2536 C CG1 . VAL A 1 323 ? -5.056 -1.501 18.404 1.00 16.98 ? 323 VAL A CG1 1 ATOM 2537 C CG2 . VAL A 1 323 ? -7.235 -0.381 19.030 1.00 15.74 ? 323 VAL A CG2 1 ATOM 2538 N N . GLN A 1 324 ? -5.267 -2.104 15.067 1.00 18.69 ? 324 GLN A N 1 ATOM 2539 C CA . GLN A 1 324 ? -4.683 -3.194 14.282 1.00 18.48 ? 324 GLN A CA 1 ATOM 2540 C C . GLN A 1 324 ? -3.449 -3.681 15.037 1.00 18.70 ? 324 GLN A C 1 ATOM 2541 O O . GLN A 1 324 ? -2.589 -2.869 15.395 1.00 17.54 ? 324 GLN A O 1 ATOM 2542 C CB . GLN A 1 324 ? -4.238 -2.700 12.886 1.00 19.00 ? 324 GLN A CB 1 ATOM 2543 C CG . GLN A 1 324 ? -3.650 -3.800 11.996 1.00 17.55 ? 324 GLN A CG 1 ATOM 2544 C CD . GLN A 1 324 ? -4.567 -5.029 11.859 1.00 19.74 ? 324 GLN A CD 1 ATOM 2545 O OE1 . GLN A 1 324 ? -5.808 -4.915 11.678 1.00 16.05 ? 324 GLN A OE1 1 ATOM 2546 N NE2 . GLN A 1 324 ? -3.961 -6.216 11.944 1.00 19.31 ? 324 GLN A NE2 1 ATOM 2547 N N . HIS A 1 325 ? -3.357 -4.994 15.270 1.00 18.83 ? 325 HIS A N 1 ATOM 2548 C CA . HIS A 1 325 ? -2.184 -5.549 15.952 1.00 18.57 ? 325 HIS A CA 1 ATOM 2549 C C . HIS A 1 325 ? -1.244 -6.134 14.908 1.00 18.95 ? 325 HIS A C 1 ATOM 2550 O O . HIS A 1 325 ? -1.686 -6.715 13.914 1.00 20.19 ? 325 HIS A O 1 ATOM 2551 C CB . HIS A 1 325 ? -2.579 -6.604 17.017 1.00 18.78 ? 325 HIS A CB 1 ATOM 2552 C CG . HIS A 1 325 ? -3.364 -6.037 18.170 1.00 18.13 ? 325 HIS A CG 1 ATOM 2553 N ND1 . HIS A 1 325 ? -3.219 -6.484 19.460 1.00 15.98 ? 325 HIS A ND1 1 ATOM 2554 C CD2 . HIS A 1 325 ? -4.293 -5.050 18.222 1.00 16.91 ? 325 HIS A CD2 1 ATOM 2555 C CE1 . HIS A 1 325 ? -3.991 -5.777 20.267 1.00 15.99 ? 325 HIS A CE1 1 ATOM 2556 N NE2 . HIS A 1 325 ? -4.675 -4.918 19.535 1.00 18.16 ? 325 HIS A NE2 1 ATOM 2557 N N . ALA A 1 326 ? 0.048 -5.940 15.115 1.00 18.46 ? 326 ALA A N 1 ATOM 2558 C CA . ALA A 1 326 ? 1.067 -6.505 14.211 1.00 18.70 ? 326 ALA A CA 1 ATOM 2559 C C . ALA A 1 326 ? 1.810 -7.562 15.033 1.00 18.06 ? 326 ALA A C 1 ATOM 2560 O O . ALA A 1 326 ? 2.455 -7.218 16.012 1.00 17.73 ? 326 ALA A O 1 ATOM 2561 C CB . ALA A 1 326 ? 2.044 -5.381 13.717 1.00 17.62 ? 326 ALA A CB 1 ATOM 2562 N N . ASP A 1 327 ? 1.664 -8.830 14.648 1.00 18.43 ? 327 ASP A N 1 ATOM 2563 C CA . ASP A 1 327 ? 2.277 -9.959 15.334 1.00 19.60 ? 327 ASP A CA 1 ATOM 2564 C C . ASP A 1 327 ? 3.761 -10.118 14.888 1.00 20.31 ? 327 ASP A C 1 ATOM 2565 O O . ASP A 1 327 ? 4.280 -9.264 14.186 1.00 20.64 ? 327 ASP A O 1 ATOM 2566 C CB . ASP A 1 327 ? 1.455 -11.222 15.070 1.00 19.13 ? 327 ASP A CB 1 ATOM 2567 C CG . ASP A 1 327 ? 1.584 -12.256 16.165 1.00 18.47 ? 327 ASP A CG 1 ATOM 2568 O OD1 . ASP A 1 327 ? 2.668 -12.401 16.771 1.00 19.35 ? 327 ASP A OD1 1 ATOM 2569 O OD2 . ASP A 1 327 ? 0.614 -12.991 16.379 1.00 17.92 ? 327 ASP A OD2 1 ATOM 2570 N N . ILE A 1 328 ? 4.431 -11.199 15.267 1.00 21.21 ? 328 ILE A N 1 ATOM 2571 C CA . ILE A 1 328 ? 5.885 -11.318 14.970 1.00 22.04 ? 328 ILE A CA 1 ATOM 2572 C C . ILE A 1 328 ? 6.260 -11.352 13.474 1.00 22.58 ? 328 ILE A C 1 ATOM 2573 O O . ILE A 1 328 ? 7.428 -11.142 13.152 1.00 22.76 ? 328 ILE A O 1 ATOM 2574 C CB . ILE A 1 328 ? 6.595 -12.496 15.727 1.00 21.97 ? 328 ILE A CB 1 ATOM 2575 C CG1 . ILE A 1 328 ? 5.885 -13.830 15.458 1.00 21.77 ? 328 ILE A CG1 1 ATOM 2576 C CG2 . ILE A 1 328 ? 6.700 -12.189 17.198 1.00 21.06 ? 328 ILE A CG2 1 ATOM 2577 C CD1 . ILE A 1 328 ? 6.512 -15.049 16.162 1.00 22.57 ? 328 ILE A CD1 1 ATOM 2578 N N . ASP A 1 329 ? 5.304 -11.597 12.563 1.00 22.00 ? 329 ASP A N 1 ATOM 2579 C CA . ASP A 1 329 ? 5.631 -11.483 11.131 1.00 22.49 ? 329 ASP A CA 1 ATOM 2580 C C . ASP A 1 329 ? 6.113 -10.116 10.641 1.00 22.03 ? 329 ASP A C 1 ATOM 2581 O O . ASP A 1 329 ? 6.727 -10.084 9.593 1.00 22.79 ? 329 ASP A O 1 ATOM 2582 C CB . ASP A 1 329 ? 4.558 -12.069 10.188 1.00 23.11 ? 329 ASP A CB 1 ATOM 2583 C CG . ASP A 1 329 ? 3.138 -11.683 10.582 1.00 24.92 ? 329 ASP A CG 1 ATOM 2584 O OD1 . ASP A 1 329 ? 2.773 -11.773 11.791 1.00 25.58 ? 329 ASP A OD1 1 ATOM 2585 O OD2 . ASP A 1 329 ? 2.372 -11.345 9.664 1.00 28.97 ? 329 ASP A OD2 1 ATOM 2586 N N . TYR A 1 330 ? 5.872 -9.013 11.383 1.00 21.95 ? 330 TYR A N 1 ATOM 2587 C CA . TYR A 1 330 ? 6.396 -7.663 11.010 1.00 21.13 ? 330 TYR A CA 1 ATOM 2588 C C . TYR A 1 330 ? 7.920 -7.549 11.146 1.00 21.30 ? 330 TYR A C 1 ATOM 2589 O O . TYR A 1 330 ? 8.557 -6.747 10.464 1.00 20.47 ? 330 TYR A O 1 ATOM 2590 C CB . TYR A 1 330 ? 5.691 -6.488 11.743 1.00 20.43 ? 330 TYR A CB 1 ATOM 2591 C CG . TYR A 1 330 ? 6.177 -6.172 13.163 1.00 20.19 ? 330 TYR A CG 1 ATOM 2592 C CD1 . TYR A 1 330 ? 7.368 -5.468 13.382 1.00 18.68 ? 330 TYR A CD1 1 ATOM 2593 C CD2 . TYR A 1 330 ? 5.446 -6.583 14.281 1.00 18.12 ? 330 TYR A CD2 1 ATOM 2594 C CE1 . TYR A 1 330 ? 7.834 -5.205 14.674 1.00 19.61 ? 330 TYR A CE1 1 ATOM 2595 C CE2 . TYR A 1 330 ? 5.901 -6.329 15.588 1.00 17.78 ? 330 TYR A CE2 1 ATOM 2596 C CZ . TYR A 1 330 ? 7.083 -5.625 15.772 1.00 18.66 ? 330 TYR A CZ 1 ATOM 2597 O OH . TYR A 1 330 ? 7.536 -5.360 17.034 1.00 18.88 ? 330 TYR A OH 1 ATOM 2598 N N . MET A 1 331 ? 8.484 -8.359 12.026 1.00 21.12 ? 331 MET A N 1 ATOM 2599 C CA . MET A 1 331 ? 9.876 -8.264 12.384 1.00 21.79 ? 331 MET A CA 1 ATOM 2600 C C . MET A 1 331 ? 10.785 -8.850 11.302 1.00 21.90 ? 331 MET A C 1 ATOM 2601 O O . MET A 1 331 ? 10.360 -9.627 10.460 1.00 22.12 ? 331 MET A O 1 ATOM 2602 C CB . MET A 1 331 ? 10.121 -8.990 13.711 1.00 21.42 ? 331 MET A CB 1 ATOM 2603 C CG . MET A 1 331 ? 9.226 -8.564 14.885 1.00 22.34 ? 331 MET A CG 1 ATOM 2604 S SD . MET A 1 331 ? 9.535 -9.607 16.305 1.00 22.91 ? 331 MET A SD 1 ATOM 2605 C CE . MET A 1 331 ? 8.519 -8.785 17.575 1.00 21.66 ? 331 MET A CE 1 ATOM 2606 N N . ASP A 1 332 ? 12.055 -8.484 11.357 1.00 23.65 ? 332 ASP A N 1 ATOM 2607 C CA . ASP A 1 332 ? 13.053 -9.079 10.482 1.00 24.52 ? 332 ASP A CA 1 ATOM 2608 C C . ASP A 1 332 ? 13.503 -10.357 11.175 1.00 24.60 ? 332 ASP A C 1 ATOM 2609 O O . ASP A 1 332 ? 14.250 -10.309 12.147 1.00 24.71 ? 332 ASP A O 1 ATOM 2610 C CB . ASP A 1 332 ? 14.227 -8.116 10.315 1.00 25.41 ? 332 ASP A CB 1 ATOM 2611 C CG . ASP A 1 332 ? 15.298 -8.636 9.360 1.00 28.17 ? 332 ASP A CG 1 ATOM 2612 O OD1 . ASP A 1 332 ? 15.094 -9.689 8.704 1.00 28.74 ? 332 ASP A OD1 1 ATOM 2613 O OD2 . ASP A 1 332 ? 16.343 -7.947 9.266 1.00 33.97 ? 332 ASP A OD2 1 ATOM 2614 N N . GLU A 1 333 ? 13.020 -11.496 10.693 1.00 25.39 ? 333 GLU A N 1 ATOM 2615 C CA . GLU A 1 333 ? 13.408 -12.806 11.261 1.00 26.18 ? 333 GLU A CA 1 ATOM 2616 C C . GLU A 1 333 ? 13.061 -12.923 12.756 1.00 24.82 ? 333 GLU A C 1 ATOM 2617 O O . GLU A 1 333 ? 13.833 -13.465 13.566 1.00 23.46 ? 333 GLU A O 1 ATOM 2618 C CB . GLU A 1 333 ? 14.901 -13.108 11.014 1.00 27.24 ? 333 GLU A CB 1 ATOM 2619 C CG . GLU A 1 333 ? 15.331 -13.047 9.544 1.00 31.99 ? 333 GLU A CG 1 ATOM 2620 C CD . GLU A 1 333 ? 14.905 -14.258 8.745 1.00 39.66 ? 333 GLU A CD 1 ATOM 2621 O OE1 . GLU A 1 333 ? 13.784 -14.794 8.980 1.00 41.23 ? 333 GLU A OE1 1 ATOM 2622 O OE2 . GLU A 1 333 ? 15.693 -14.669 7.854 1.00 41.45 ? 333 GLU A OE2 1 ATOM 2623 N N . ARG A 1 334 ? 11.889 -12.389 13.100 1.00 23.53 ? 334 ARG A N 1 ATOM 2624 C CA . ARG A 1 334 ? 11.311 -12.547 14.424 1.00 23.21 ? 334 ARG A CA 1 ATOM 2625 C C . ARG A 1 334 ? 12.138 -11.933 15.533 1.00 22.61 ? 334 ARG A C 1 ATOM 2626 O O . ARG A 1 334 ? 12.125 -12.397 16.671 1.00 22.35 ? 334 ARG A O 1 ATOM 2627 C CB . ARG A 1 334 ? 10.991 -14.031 14.661 1.00 23.35 ? 334 ARG A CB 1 ATOM 2628 C CG . ARG A 1 334 ? 9.843 -14.481 13.731 1.00 24.02 ? 334 ARG A CG 1 ATOM 2629 C CD . ARG A 1 334 ? 9.686 -15.979 13.571 1.00 26.39 ? 334 ARG A CD 1 ATOM 2630 N NE . ARG A 1 334 ? 8.327 -16.278 13.102 1.00 29.03 ? 334 ARG A NE 1 ATOM 2631 C CZ . ARG A 1 334 ? 7.705 -17.447 13.281 1.00 30.02 ? 334 ARG A CZ 1 ATOM 2632 N NH1 . ARG A 1 334 ? 8.318 -18.456 13.909 1.00 28.35 ? 334 ARG A NH1 1 ATOM 2633 N NH2 . ARG A 1 334 ? 6.474 -17.611 12.828 1.00 27.69 ? 334 ARG A NH2 1 ATOM 2634 N N . ARG A 1 335 ? 12.848 -10.862 15.197 1.00 22.81 ? 335 ARG A N 1 ATOM 2635 C CA . ARG A 1 335 ? 13.723 -10.170 16.150 1.00 22.64 ? 335 ARG A CA 1 ATOM 2636 C C . ARG A 1 335 ? 13.126 -8.821 16.525 1.00 22.07 ? 335 ARG A C 1 ATOM 2637 O O . ARG A 1 335 ? 12.693 -8.076 15.636 1.00 21.74 ? 335 ARG A O 1 ATOM 2638 C CB . ARG A 1 335 ? 15.118 -9.951 15.546 1.00 22.18 ? 335 ARG A CB 1 ATOM 2639 C CG . ARG A 1 335 ? 15.980 -11.197 15.426 1.00 23.68 ? 335 ARG A CG 1 ATOM 2640 C CD . ARG A 1 335 ? 17.394 -10.833 14.984 1.00 24.83 ? 335 ARG A CD 1 ATOM 2641 N NE . ARG A 1 335 ? 17.324 -10.154 13.702 1.00 32.88 ? 335 ARG A NE 1 ATOM 2642 C CZ . ARG A 1 335 ? 18.349 -9.578 13.096 1.00 37.54 ? 335 ARG A CZ 1 ATOM 2643 N NH1 . ARG A 1 335 ? 18.138 -8.984 11.920 1.00 37.86 ? 335 ARG A NH1 1 ATOM 2644 N NH2 . ARG A 1 335 ? 19.569 -9.597 13.658 1.00 34.21 ? 335 ARG A NH2 1 ATOM 2645 N N . ASP A 1 336 ? 13.088 -8.515 17.828 1.00 21.48 ? 336 ASP A N 1 ATOM 2646 C CA . ASP A 1 336 ? 12.576 -7.229 18.329 1.00 21.49 ? 336 ASP A CA 1 ATOM 2647 C C . ASP A 1 336 ? 13.259 -6.057 17.654 1.00 21.80 ? 336 ASP A C 1 ATOM 2648 O O . ASP A 1 336 ? 14.477 -6.134 17.312 1.00 21.96 ? 336 ASP A O 1 ATOM 2649 C CB . ASP A 1 336 ? 12.828 -7.073 19.829 1.00 21.07 ? 336 ASP A CB 1 ATOM 2650 C CG . ASP A 1 336 ? 11.858 -7.852 20.690 1.00 23.72 ? 336 ASP A CG 1 ATOM 2651 O OD1 . ASP A 1 336 ? 10.802 -8.320 20.174 1.00 19.81 ? 336 ASP A OD1 1 ATOM 2652 O OD2 . ASP A 1 336 ? 12.168 -7.969 21.914 1.00 23.60 ? 336 ASP A OD2 1 ATOM 2653 N N . PHE A 1 337 ? 12.488 -4.976 17.499 1.00 21.04 ? 337 PHE A N 1 ATOM 2654 C CA . PHE A 1 337 ? 12.988 -3.630 17.142 1.00 21.60 ? 337 PHE A CA 1 ATOM 2655 C C . PHE A 1 337 ? 13.578 -3.518 15.726 1.00 21.44 ? 337 PHE A C 1 ATOM 2656 O O . PHE A 1 337 ? 14.428 -2.660 15.453 1.00 22.11 ? 337 PHE A O 1 ATOM 2657 C CB . PHE A 1 337 ? 13.945 -3.055 18.200 1.00 20.52 ? 337 PHE A CB 1 ATOM 2658 C CG . PHE A 1 337 ? 13.448 -3.198 19.606 1.00 21.56 ? 337 PHE A CG 1 ATOM 2659 C CD1 . PHE A 1 337 ? 12.228 -2.611 20.002 1.00 18.86 ? 337 PHE A CD1 1 ATOM 2660 C CD2 . PHE A 1 337 ? 14.178 -3.938 20.536 1.00 18.30 ? 337 PHE A CD2 1 ATOM 2661 C CE1 . PHE A 1 337 ? 11.765 -2.762 21.320 1.00 19.12 ? 337 PHE A CE1 1 ATOM 2662 C CE2 . PHE A 1 337 ? 13.708 -4.106 21.839 1.00 19.89 ? 337 PHE A CE2 1 ATOM 2663 C CZ . PHE A 1 337 ? 12.487 -3.508 22.218 1.00 19.52 ? 337 PHE A CZ 1 ATOM 2664 N N . THR A 1 338 ? 13.084 -4.394 14.859 1.00 21.74 ? 338 THR A N 1 ATOM 2665 C CA . THR A 1 338 ? 13.294 -4.377 13.432 1.00 22.27 ? 338 THR A CA 1 ATOM 2666 C C . THR A 1 338 ? 11.947 -4.588 12.754 1.00 22.87 ? 338 THR A C 1 ATOM 2667 O O . THR A 1 338 ? 10.999 -5.060 13.385 1.00 22.84 ? 338 THR A O 1 ATOM 2668 C CB . THR A 1 338 ? 14.152 -5.562 12.995 1.00 22.23 ? 338 THR A CB 1 ATOM 2669 O OG1 . THR A 1 338 ? 13.439 -6.777 13.250 1.00 22.51 ? 338 THR A OG1 1 ATOM 2670 C CG2 . THR A 1 338 ? 15.523 -5.582 13.734 1.00 22.57 ? 338 THR A CG2 1 ATOM 2671 N N . TYR A 1 339 ? 11.871 -4.273 11.465 1.00 23.99 ? 339 TYR A N 1 ATOM 2672 C CA . TYR A 1 339 ? 10.801 -4.823 10.631 1.00 24.57 ? 339 TYR A CA 1 ATOM 2673 C C . TYR A 1 339 ? 11.358 -5.436 9.327 1.00 25.00 ? 339 TYR A C 1 ATOM 2674 O O . TYR A 1 339 ? 12.465 -5.101 8.905 1.00 24.65 ? 339 TYR A O 1 ATOM 2675 C CB . TYR A 1 339 ? 9.688 -3.793 10.399 1.00 24.70 ? 339 TYR A CB 1 ATOM 2676 C CG . TYR A 1 339 ? 10.053 -2.587 9.561 1.00 24.73 ? 339 TYR A CG 1 ATOM 2677 C CD1 . TYR A 1 339 ? 9.940 -2.632 8.176 1.00 26.11 ? 339 TYR A CD1 1 ATOM 2678 C CD2 . TYR A 1 339 ? 10.466 -1.394 10.144 1.00 24.54 ? 339 TYR A CD2 1 ATOM 2679 C CE1 . TYR A 1 339 ? 10.264 -1.546 7.392 1.00 26.18 ? 339 TYR A CE1 1 ATOM 2680 C CE2 . TYR A 1 339 ? 10.800 -0.283 9.351 1.00 23.89 ? 339 TYR A CE2 1 ATOM 2681 C CZ . TYR A 1 339 ? 10.674 -0.379 7.976 1.00 24.81 ? 339 TYR A CZ 1 ATOM 2682 O OH . TYR A 1 339 ? 10.968 0.682 7.139 1.00 27.87 ? 339 TYR A OH 1 ATOM 2683 N N . ASP A 1 340 ? 10.596 -6.332 8.699 1.00 25.39 ? 340 ASP A N 1 ATOM 2684 C CA . ASP A 1 340 ? 11.045 -7.014 7.486 1.00 26.04 ? 340 ASP A CA 1 ATOM 2685 C C . ASP A 1 340 ? 11.012 -6.037 6.299 1.00 26.46 ? 340 ASP A C 1 ATOM 2686 O O . ASP A 1 340 ? 9.946 -5.653 5.816 1.00 25.85 ? 340 ASP A O 1 ATOM 2687 C CB . ASP A 1 340 ? 10.194 -8.262 7.247 1.00 26.34 ? 340 ASP A CB 1 ATOM 2688 C CG . ASP A 1 340 ? 10.734 -9.156 6.130 1.00 27.62 ? 340 ASP A CG 1 ATOM 2689 O OD1 . ASP A 1 340 ? 11.245 -8.654 5.112 1.00 31.56 ? 340 ASP A OD1 1 ATOM 2690 O OD2 . ASP A 1 340 ? 10.618 -10.382 6.248 1.00 31.67 ? 340 ASP A OD2 1 ATOM 2691 N N . SER A 1 341 ? 12.200 -5.632 5.851 1.00 27.24 ? 341 SER A N 1 ATOM 2692 C CA . SER A 1 341 ? 12.375 -4.592 4.833 1.00 28.13 ? 341 SER A CA 1 ATOM 2693 C C . SER A 1 341 ? 11.882 -4.995 3.447 1.00 28.23 ? 341 SER A C 1 ATOM 2694 O O . SER A 1 341 ? 11.783 -4.153 2.575 1.00 29.58 ? 341 SER A O 1 ATOM 2695 C CB . SER A 1 341 ? 13.855 -4.173 4.764 1.00 29.08 ? 341 SER A CB 1 ATOM 2696 O OG . SER A 1 341 ? 14.650 -5.288 4.365 1.00 32.17 ? 341 SER A OG 1 ATOM 2697 N N . VAL A 1 342 ? 11.561 -6.275 3.256 1.00 28.27 ? 342 VAL A N 1 ATOM 2698 C CA . VAL A 1 342 ? 10.974 -6.805 2.022 1.00 27.91 ? 342 VAL A CA 1 ATOM 2699 C C . VAL A 1 342 ? 9.468 -7.136 2.187 1.00 28.11 ? 342 VAL A C 1 ATOM 2700 O O . VAL A 1 342 ? 8.618 -6.565 1.516 1.00 27.80 ? 342 VAL A O 1 ATOM 2701 C CB . VAL A 1 342 ? 11.759 -8.060 1.535 1.00 27.97 ? 342 VAL A CB 1 ATOM 2702 C CG1 . VAL A 1 342 ? 11.082 -8.699 0.332 1.00 28.57 ? 342 VAL A CG1 1 ATOM 2703 C CG2 . VAL A 1 342 ? 13.233 -7.686 1.212 1.00 27.88 ? 342 VAL A CG2 1 ATOM 2704 N N . ASP A 1 343 ? 9.145 -8.058 3.081 1.00 27.70 ? 343 ASP A N 1 ATOM 2705 C CA . ASP A 1 343 ? 7.751 -8.433 3.315 1.00 27.81 ? 343 ASP A CA 1 ATOM 2706 C C . ASP A 1 343 ? 6.902 -7.307 3.928 1.00 26.88 ? 343 ASP A C 1 ATOM 2707 O O . ASP A 1 343 ? 5.682 -7.236 3.700 1.00 28.04 ? 343 ASP A O 1 ATOM 2708 C CB . ASP A 1 343 ? 7.701 -9.708 4.164 1.00 28.01 ? 343 ASP A CB 1 ATOM 2709 C CG . ASP A 1 343 ? 8.087 -10.963 3.364 1.00 30.26 ? 343 ASP A CG 1 ATOM 2710 O OD1 . ASP A 1 343 ? 8.235 -10.871 2.125 1.00 32.06 ? 343 ASP A OD1 1 ATOM 2711 O OD2 . ASP A 1 343 ? 8.212 -12.052 3.976 1.00 31.26 ? 343 ASP A OD2 1 ATOM 2712 N N . PHE A 1 344 ? 7.550 -6.427 4.681 1.00 25.53 ? 344 PHE A N 1 ATOM 2713 C CA . PHE A 1 344 ? 6.897 -5.295 5.333 1.00 25.16 ? 344 PHE A CA 1 ATOM 2714 C C . PHE A 1 344 ? 7.514 -3.967 4.917 1.00 25.25 ? 344 PHE A C 1 ATOM 2715 O O . PHE A 1 344 ? 7.538 -3.019 5.694 1.00 24.84 ? 344 PHE A O 1 ATOM 2716 C CB . PHE A 1 344 ? 6.872 -5.456 6.865 1.00 24.44 ? 344 PHE A CB 1 ATOM 2717 C CG . PHE A 1 344 ? 5.755 -6.358 7.352 1.00 23.18 ? 344 PHE A CG 1 ATOM 2718 C CD1 . PHE A 1 344 ? 5.858 -7.747 7.240 1.00 22.15 ? 344 PHE A CD1 1 ATOM 2719 C CD2 . PHE A 1 344 ? 4.587 -5.817 7.906 1.00 23.61 ? 344 PHE A CD2 1 ATOM 2720 C CE1 . PHE A 1 344 ? 4.806 -8.587 7.680 1.00 22.09 ? 344 PHE A CE1 1 ATOM 2721 C CE2 . PHE A 1 344 ? 3.533 -6.659 8.345 1.00 21.05 ? 344 PHE A CE2 1 ATOM 2722 C CZ . PHE A 1 344 ? 3.649 -8.028 8.222 1.00 21.25 ? 344 PHE A CZ 1 ATOM 2723 N N . LYS A 1 345 ? 7.959 -3.895 3.658 1.00 25.86 ? 345 LYS A N 1 ATOM 2724 C CA . LYS A 1 345 ? 8.492 -2.649 3.095 1.00 26.72 ? 345 LYS A CA 1 ATOM 2725 C C . LYS A 1 345 ? 7.346 -1.656 3.003 1.00 26.63 ? 345 LYS A C 1 ATOM 2726 O O . LYS A 1 345 ? 6.256 -1.982 2.501 1.00 25.95 ? 345 LYS A O 1 ATOM 2727 C CB . LYS A 1 345 ? 9.106 -2.892 1.708 1.00 27.16 ? 345 LYS A CB 1 ATOM 2728 C CG . LYS A 1 345 ? 9.586 -1.612 1.003 1.00 28.31 ? 345 LYS A CG 1 ATOM 2729 C CD . LYS A 1 345 ? 9.804 -1.844 -0.507 1.00 28.10 ? 345 LYS A CD 1 ATOM 2730 C CE . LYS A 1 345 ? 10.323 -0.577 -1.193 1.00 30.05 ? 345 LYS A CE 1 ATOM 2731 N NZ . LYS A 1 345 ? 10.301 -0.702 -2.693 1.00 31.24 ? 345 LYS A NZ 1 ATOM 2732 N N . GLY A 1 346 ? 7.575 -0.449 3.499 1.00 26.68 ? 346 GLY A N 1 ATOM 2733 C CA . GLY A 1 346 ? 6.491 0.528 3.531 1.00 27.08 ? 346 GLY A CA 1 ATOM 2734 C C . GLY A 1 346 ? 5.675 0.470 4.800 1.00 26.90 ? 346 GLY A C 1 ATOM 2735 O O . GLY A 1 346 ? 4.602 1.065 4.871 1.00 28.21 ? 346 GLY A O 1 ATOM 2736 N N . PHE A 1 347 ? 6.165 -0.257 5.805 1.00 26.64 ? 347 PHE A N 1 ATOM 2737 C CA . PHE A 1 347 ? 5.533 -0.267 7.146 1.00 25.86 ? 347 PHE A CA 1 ATOM 2738 C C . PHE A 1 347 ? 5.249 1.148 7.696 1.00 25.49 ? 347 PHE A C 1 ATOM 2739 O O . PHE A 1 347 ? 4.114 1.398 8.156 1.00 25.89 ? 347 PHE A O 1 ATOM 2740 C CB . PHE A 1 347 ? 6.317 -1.146 8.165 1.00 25.54 ? 347 PHE A CB 1 ATOM 2741 C CG . PHE A 1 347 ? 5.466 -1.721 9.298 1.00 25.42 ? 347 PHE A CG 1 ATOM 2742 C CD1 . PHE A 1 347 ? 4.082 -1.910 9.154 1.00 25.08 ? 347 PHE A CD1 1 ATOM 2743 C CD2 . PHE A 1 347 ? 6.067 -2.131 10.480 1.00 23.96 ? 347 PHE A CD2 1 ATOM 2744 C CE1 . PHE A 1 347 ? 3.309 -2.452 10.201 1.00 25.85 ? 347 PHE A CE1 1 ATOM 2745 C CE2 . PHE A 1 347 ? 5.309 -2.677 11.531 1.00 25.74 ? 347 PHE A CE2 1 ATOM 2746 C CZ . PHE A 1 347 ? 3.928 -2.835 11.386 1.00 25.57 ? 347 PHE A CZ 1 ATOM 2747 N N . PRO A 1 348 ? 6.247 2.082 7.645 1.00 24.22 ? 348 PRO A N 1 ATOM 2748 C CA . PRO A 1 348 ? 5.936 3.418 8.154 1.00 23.24 ? 348 PRO A CA 1 ATOM 2749 C C . PRO A 1 348 ? 4.784 4.125 7.414 1.00 23.07 ? 348 PRO A C 1 ATOM 2750 O O . PRO A 1 348 ? 4.028 4.844 8.076 1.00 22.57 ? 348 PRO A O 1 ATOM 2751 C CB . PRO A 1 348 ? 7.242 4.182 7.959 1.00 23.73 ? 348 PRO A CB 1 ATOM 2752 C CG . PRO A 1 348 ? 8.307 3.109 7.913 1.00 23.40 ? 348 PRO A CG 1 ATOM 2753 C CD . PRO A 1 348 ? 7.642 2.015 7.162 1.00 24.13 ? 348 PRO A CD 1 ATOM 2754 N N . GLU A 1 349 ? 4.667 3.930 6.092 1.00 22.01 ? 349 GLU A N 1 ATOM 2755 C CA . GLU A 1 349 ? 3.602 4.539 5.277 1.00 23.42 ? 349 GLU A CA 1 ATOM 2756 C C . GLU A 1 349 ? 2.221 3.960 5.684 1.00 22.69 ? 349 GLU A C 1 ATOM 2757 O O . GLU A 1 349 ? 1.231 4.679 5.724 1.00 22.81 ? 349 GLU A O 1 ATOM 2758 C CB . GLU A 1 349 ? 3.827 4.310 3.766 1.00 23.64 ? 349 GLU A CB 1 ATOM 2759 C CG . GLU A 1 349 ? 4.995 5.090 3.076 1.00 27.41 ? 349 GLU A CG 1 ATOM 2760 C CD . GLU A 1 349 ? 6.295 4.279 2.977 1.00 31.96 ? 349 GLU A CD 1 ATOM 2761 O OE1 . GLU A 1 349 ? 6.817 3.860 4.042 1.00 31.12 ? 349 GLU A OE1 1 ATOM 2762 O OE2 . GLU A 1 349 ? 6.786 4.057 1.830 1.00 32.51 ? 349 GLU A OE2 1 ATOM 2763 N N . PHE A 1 350 ? 2.181 2.654 5.936 1.00 22.68 ? 350 PHE A N 1 ATOM 2764 C CA . PHE A 1 350 ? 0.985 1.946 6.440 1.00 23.32 ? 350 PHE A CA 1 ATOM 2765 C C . PHE A 1 350 ? 0.579 2.474 7.825 1.00 23.20 ? 350 PHE A C 1 ATOM 2766 O O . PHE A 1 350 ? -0.606 2.634 8.117 1.00 23.51 ? 350 PHE A O 1 ATOM 2767 C CB . PHE A 1 350 ? 1.222 0.426 6.453 1.00 23.31 ? 350 PHE A CB 1 ATOM 2768 C CG . PHE A 1 350 ? 0.212 -0.357 7.264 1.00 23.76 ? 350 PHE A CG 1 ATOM 2769 C CD1 . PHE A 1 350 ? -1.012 -0.735 6.705 1.00 25.35 ? 350 PHE A CD1 1 ATOM 2770 C CD2 . PHE A 1 350 ? 0.493 -0.726 8.584 1.00 22.05 ? 350 PHE A CD2 1 ATOM 2771 C CE1 . PHE A 1 350 ? -1.951 -1.477 7.453 1.00 25.18 ? 350 PHE A CE1 1 ATOM 2772 C CE2 . PHE A 1 350 ? -0.429 -1.462 9.330 1.00 24.60 ? 350 PHE A CE2 1 ATOM 2773 C CZ . PHE A 1 350 ? -1.648 -1.841 8.764 1.00 23.75 ? 350 PHE A CZ 1 ATOM 2774 N N . VAL A 1 351 ? 1.561 2.769 8.666 1.00 22.62 ? 351 VAL A N 1 ATOM 2775 C CA . VAL A 1 351 ? 1.296 3.403 9.958 1.00 22.79 ? 351 VAL A CA 1 ATOM 2776 C C . VAL A 1 351 ? 0.581 4.767 9.807 1.00 22.55 ? 351 VAL A C 1 ATOM 2777 O O . VAL A 1 351 ? -0.417 5.013 10.503 1.00 23.02 ? 351 VAL A O 1 ATOM 2778 C CB . VAL A 1 351 ? 2.565 3.464 10.821 1.00 22.38 ? 351 VAL A CB 1 ATOM 2779 C CG1 . VAL A 1 351 ? 2.405 4.403 11.993 1.00 23.44 ? 351 VAL A CG1 1 ATOM 2780 C CG2 . VAL A 1 351 ? 2.879 2.080 11.328 1.00 23.72 ? 351 VAL A CG2 1 ATOM 2781 N N . ASN A 1 352 ? 1.054 5.606 8.872 1.00 21.38 ? 352 ASN A N 1 ATOM 2782 C CA . ASN A 1 352 ? 0.382 6.866 8.523 1.00 20.81 ? 352 ASN A CA 1 ATOM 2783 C C . ASN A 1 352 ? -1.037 6.651 7.998 1.00 20.22 ? 352 ASN A C 1 ATOM 2784 O O . ASN A 1 352 ? -1.897 7.482 8.246 1.00 19.64 ? 352 ASN A O 1 ATOM 2785 C CB . ASN A 1 352 ? 1.136 7.655 7.450 1.00 20.01 ? 352 ASN A CB 1 ATOM 2786 C CG . ASN A 1 352 ? 2.428 8.302 7.951 1.00 22.82 ? 352 ASN A CG 1 ATOM 2787 O OD1 . ASN A 1 352 ? 2.785 8.257 9.136 1.00 22.97 ? 352 ASN A OD1 1 ATOM 2788 N ND2 . ASN A 1 352 ? 3.133 8.935 7.022 1.00 24.68 ? 352 ASN A ND2 1 ATOM 2789 N N . GLU A 1 353 ? -1.246 5.594 7.212 1.00 19.69 ? 353 GLU A N 1 ATOM 2790 C CA . GLU A 1 353 ? -2.578 5.228 6.700 1.00 20.75 ? 353 GLU A CA 1 ATOM 2791 C C . GLU A 1 353 ? -3.554 4.897 7.833 1.00 20.95 ? 353 GLU A C 1 ATOM 2792 O O . GLU A 1 353 ? -4.700 5.382 7.835 1.00 21.13 ? 353 GLU A O 1 ATOM 2793 C CB . GLU A 1 353 ? -2.505 4.053 5.693 1.00 18.95 ? 353 GLU A CB 1 ATOM 2794 C CG . GLU A 1 353 ? -1.727 4.391 4.444 1.00 22.26 ? 353 GLU A CG 1 ATOM 2795 C CD . GLU A 1 353 ? -1.416 3.200 3.550 1.00 22.47 ? 353 GLU A CD 1 ATOM 2796 O OE1 . GLU A 1 353 ? -1.428 2.046 4.029 1.00 25.73 ? 353 GLU A OE1 1 ATOM 2797 O OE2 . GLU A 1 353 ? -1.156 3.445 2.353 1.00 25.91 ? 353 GLU A OE2 1 ATOM 2798 N N . LEU A 1 354 ? -3.117 4.029 8.755 1.00 20.59 ? 354 LEU A N 1 ATOM 2799 C CA . LEU A 1 354 ? -3.882 3.727 9.973 1.00 20.33 ? 354 LEU A CA 1 ATOM 2800 C C . LEU A 1 354 ? -4.257 5.009 10.718 1.00 20.61 ? 354 LEU A C 1 ATOM 2801 O O . LEU A 1 354 ? -5.442 5.240 11.012 1.00 20.35 ? 354 LEU A O 1 ATOM 2802 C CB . LEU A 1 354 ? -3.108 2.774 10.913 1.00 20.72 ? 354 LEU A CB 1 ATOM 2803 C CG . LEU A 1 354 ? -2.956 1.300 10.534 1.00 20.06 ? 354 LEU A CG 1 ATOM 2804 C CD1 . LEU A 1 354 ? -2.094 0.660 11.578 1.00 20.27 ? 354 LEU A CD1 1 ATOM 2805 C CD2 . LEU A 1 354 ? -4.314 0.547 10.441 1.00 20.62 ? 354 LEU A CD2 1 ATOM 2806 N N . HIS A 1 355 ? -3.257 5.851 10.984 1.00 19.93 ? 355 HIS A N 1 ATOM 2807 C CA . HIS A 1 355 ? -3.452 7.074 11.727 1.00 20.60 ? 355 HIS A CA 1 ATOM 2808 C C . HIS A 1 355 ? -4.422 8.056 11.074 1.00 21.14 ? 355 HIS A C 1 ATOM 2809 O O . HIS A 1 355 ? -5.225 8.690 11.765 1.00 21.26 ? 355 HIS A O 1 ATOM 2810 C CB . HIS A 1 355 ? -2.096 7.716 12.021 1.00 20.96 ? 355 HIS A CB 1 ATOM 2811 C CG . HIS A 1 355 ? -1.287 6.948 13.021 1.00 22.21 ? 355 HIS A CG 1 ATOM 2812 N ND1 . HIS A 1 355 ? 0.068 7.142 13.192 1.00 22.76 ? 355 HIS A ND1 1 ATOM 2813 C CD2 . HIS A 1 355 ? -1.643 5.979 13.903 1.00 21.99 ? 355 HIS A CD2 1 ATOM 2814 C CE1 . HIS A 1 355 ? 0.509 6.342 14.148 1.00 22.39 ? 355 HIS A CE1 1 ATOM 2815 N NE2 . HIS A 1 355 ? -0.503 5.619 14.591 1.00 23.11 ? 355 HIS A NE2 1 ATOM 2816 N N . ASN A 1 356 ? -4.330 8.175 9.749 1.00 21.17 ? 356 ASN A N 1 ATOM 2817 C CA . ASN A 1 356 ? -5.224 9.010 8.966 1.00 22.05 ? 356 ASN A CA 1 ATOM 2818 C C . ASN A 1 356 ? -6.661 8.458 8.938 1.00 22.11 ? 356 ASN A C 1 ATOM 2819 O O . ASN A 1 356 ? -7.585 9.227 8.723 1.00 21.98 ? 356 ASN A O 1 ATOM 2820 C CB . ASN A 1 356 ? -4.706 9.156 7.532 1.00 22.34 ? 356 ASN A CB 1 ATOM 2821 C CG . ASN A 1 356 ? -5.529 10.130 6.714 1.00 24.27 ? 356 ASN A CG 1 ATOM 2822 O OD1 . ASN A 1 356 ? -5.803 11.252 7.156 1.00 28.90 ? 356 ASN A OD1 1 ATOM 2823 N ND2 . ASN A 1 356 ? -5.941 9.709 5.523 1.00 26.30 ? 356 ASN A ND2 1 ATOM 2824 N N . ASN A 1 357 ? -6.813 7.137 9.109 1.00 22.12 ? 357 ASN A N 1 ATOM 2825 C CA . ASN A 1 357 ? -8.117 6.443 9.189 1.00 22.16 ? 357 ASN A CA 1 ATOM 2826 C C . ASN A 1 357 ? -8.753 6.563 10.578 1.00 22.16 ? 357 ASN A C 1 ATOM 2827 O O . ASN A 1 357 ? -9.876 6.053 10.808 1.00 23.13 ? 357 ASN A O 1 ATOM 2828 C CB . ASN A 1 357 ? -7.994 4.925 8.899 1.00 22.21 ? 357 ASN A CB 1 ATOM 2829 C CG . ASN A 1 357 ? -7.570 4.577 7.468 1.00 22.69 ? 357 ASN A CG 1 ATOM 2830 O OD1 . ASN A 1 357 ? -7.277 3.412 7.197 1.00 29.26 ? 357 ASN A OD1 1 ATOM 2831 N ND2 . ASN A 1 357 ? -7.557 5.538 6.566 1.00 23.54 ? 357 ASN A ND2 1 ATOM 2832 N N . GLY A 1 358 ? -8.043 7.208 11.498 1.00 21.64 ? 358 GLY A N 1 ATOM 2833 C CA . GLY A 1 358 ? -8.426 7.276 12.911 1.00 21.24 ? 358 GLY A CA 1 ATOM 2834 C C . GLY A 1 358 ? -8.088 6.054 13.759 1.00 20.96 ? 358 GLY A C 1 ATOM 2835 O O . GLY A 1 358 ? -8.635 5.886 14.847 1.00 21.24 ? 358 GLY A O 1 ATOM 2836 N N . GLN A 1 359 ? -7.155 5.226 13.284 1.00 19.88 ? 359 GLN A N 1 ATOM 2837 C CA . GLN A 1 359 ? -6.843 3.947 13.891 1.00 18.76 ? 359 GLN A CA 1 ATOM 2838 C C . GLN A 1 359 ? -5.478 3.906 14.556 1.00 19.05 ? 359 GLN A C 1 ATOM 2839 O O . GLN A 1 359 ? -4.662 4.830 14.400 1.00 19.48 ? 359 GLN A O 1 ATOM 2840 C CB . GLN A 1 359 ? -6.940 2.845 12.849 1.00 18.42 ? 359 GLN A CB 1 ATOM 2841 C CG . GLN A 1 359 ? -8.337 2.565 12.356 1.00 20.03 ? 359 GLN A CG 1 ATOM 2842 C CD . GLN A 1 359 ? -8.331 1.585 11.210 1.00 22.09 ? 359 GLN A CD 1 ATOM 2843 O OE1 . GLN A 1 359 ? -7.644 1.800 10.224 1.00 22.59 ? 359 GLN A OE1 1 ATOM 2844 N NE2 . GLN A 1 359 ? -9.094 0.499 11.333 1.00 22.26 ? 359 GLN A NE2 1 ATOM 2845 N N . LYS A 1 360 ? -5.255 2.847 15.340 1.00 18.86 ? 360 LYS A N 1 ATOM 2846 C CA . LYS A 1 360 ? -4.040 2.709 16.137 1.00 18.72 ? 360 LYS A CA 1 ATOM 2847 C C . LYS A 1 360 ? -3.290 1.433 15.788 1.00 17.72 ? 360 LYS A C 1 ATOM 2848 O O . LYS A 1 360 ? -3.880 0.495 15.317 1.00 17.22 ? 360 LYS A O 1 ATOM 2849 C CB . LYS A 1 360 ? -4.401 2.760 17.619 1.00 19.36 ? 360 LYS A CB 1 ATOM 2850 C CG . LYS A 1 360 ? -5.243 4.018 18.004 1.00 20.48 ? 360 LYS A CG 1 ATOM 2851 C CD . LYS A 1 360 ? -4.380 5.274 18.186 1.00 21.13 ? 360 LYS A CD 1 ATOM 2852 C CE . LYS A 1 360 ? -5.228 6.511 18.393 1.00 23.01 ? 360 LYS A CE 1 ATOM 2853 N NZ . LYS A 1 360 ? -4.444 7.682 18.964 1.00 28.63 ? 360 LYS A NZ 1 ATOM 2854 N N . LEU A 1 361 ? -1.975 1.421 15.966 1.00 18.32 ? 361 LEU A N 1 ATOM 2855 C CA . LEU A 1 361 ? -1.185 0.216 15.709 1.00 18.37 ? 361 LEU A CA 1 ATOM 2856 C C . LEU A 1 361 ? -0.668 -0.270 17.047 1.00 17.99 ? 361 LEU A C 1 ATOM 2857 O O . LEU A 1 361 ? -0.090 0.480 17.793 1.00 18.67 ? 361 LEU A O 1 ATOM 2858 C CB . LEU A 1 361 ? 0.004 0.499 14.764 1.00 18.89 ? 361 LEU A CB 1 ATOM 2859 C CG . LEU A 1 361 ? 1.043 -0.617 14.571 1.00 18.84 ? 361 LEU A CG 1 ATOM 2860 C CD1 . LEU A 1 361 ? 0.426 -1.805 13.851 1.00 19.00 ? 361 LEU A CD1 1 ATOM 2861 C CD2 . LEU A 1 361 ? 2.327 -0.135 13.852 1.00 20.87 ? 361 LEU A CD2 1 ATOM 2862 N N . VAL A 1 362 ? -0.888 -1.540 17.350 1.00 18.23 ? 362 VAL A N 1 ATOM 2863 C CA . VAL A 1 362 ? -0.261 -2.155 18.497 1.00 17.11 ? 362 VAL A CA 1 ATOM 2864 C C . VAL A 1 362 ? 0.752 -3.170 17.957 1.00 16.71 ? 362 VAL A C 1 ATOM 2865 O O . VAL A 1 362 ? 0.413 -4.006 17.132 1.00 16.54 ? 362 VAL A O 1 ATOM 2866 C CB . VAL A 1 362 ? -1.327 -2.790 19.441 1.00 17.23 ? 362 VAL A CB 1 ATOM 2867 C CG1 . VAL A 1 362 ? -0.656 -3.682 20.490 1.00 17.51 ? 362 VAL A CG1 1 ATOM 2868 C CG2 . VAL A 1 362 ? -2.131 -1.668 20.123 1.00 15.33 ? 362 VAL A CG2 1 ATOM 2869 N N . ILE A 1 363 ? 2.008 -3.068 18.390 1.00 16.59 ? 363 ILE A N 1 ATOM 2870 C CA . ILE A 1 363 ? 3.014 -4.052 17.970 1.00 15.94 ? 363 ILE A CA 1 ATOM 2871 C C . ILE A 1 363 ? 3.306 -5.011 19.098 1.00 14.94 ? 363 ILE A C 1 ATOM 2872 O O . ILE A 1 363 ? 3.322 -4.619 20.265 1.00 13.25 ? 363 ILE A O 1 ATOM 2873 C CB . ILE A 1 363 ? 4.381 -3.393 17.519 1.00 16.53 ? 363 ILE A CB 1 ATOM 2874 C CG1 . ILE A 1 363 ? 4.904 -2.387 18.560 1.00 16.00 ? 363 ILE A CG1 1 ATOM 2875 C CG2 . ILE A 1 363 ? 4.220 -2.729 16.147 1.00 18.17 ? 363 ILE A CG2 1 ATOM 2876 C CD1 . ILE A 1 363 ? 6.445 -2.061 18.443 1.00 16.44 ? 363 ILE A CD1 1 ATOM 2877 N N . ILE A 1 364 ? 3.541 -6.266 18.738 1.00 14.88 ? 364 ILE A N 1 ATOM 2878 C CA . ILE A 1 364 ? 3.998 -7.265 19.674 1.00 16.63 ? 364 ILE A CA 1 ATOM 2879 C C . ILE A 1 364 ? 5.511 -7.022 19.866 1.00 17.31 ? 364 ILE A C 1 ATOM 2880 O O . ILE A 1 364 ? 6.209 -6.621 18.926 1.00 15.47 ? 364 ILE A O 1 ATOM 2881 C CB . ILE A 1 364 ? 3.692 -8.712 19.166 1.00 16.27 ? 364 ILE A CB 1 ATOM 2882 C CG1 . ILE A 1 364 ? 3.623 -9.704 20.324 1.00 18.51 ? 364 ILE A CG1 1 ATOM 2883 C CG2 . ILE A 1 364 ? 4.705 -9.186 18.115 1.00 17.32 ? 364 ILE A CG2 1 ATOM 2884 C CD1 . ILE A 1 364 ? 2.884 -11.032 19.992 1.00 17.84 ? 364 ILE A CD1 1 ATOM 2885 N N . VAL A 1 365 ? 5.962 -7.186 21.102 1.00 18.15 ? 365 VAL A N 1 ATOM 2886 C CA . VAL A 1 365 ? 7.377 -7.201 21.441 1.00 19.81 ? 365 VAL A CA 1 ATOM 2887 C C . VAL A 1 365 ? 7.562 -8.382 22.399 1.00 20.26 ? 365 VAL A C 1 ATOM 2888 O O . VAL A 1 365 ? 6.675 -8.688 23.220 1.00 19.03 ? 365 VAL A O 1 ATOM 2889 C CB . VAL A 1 365 ? 7.897 -5.860 22.087 1.00 20.22 ? 365 VAL A CB 1 ATOM 2890 C CG1 . VAL A 1 365 ? 9.445 -5.858 22.217 1.00 22.00 ? 365 VAL A CG1 1 ATOM 2891 C CG2 . VAL A 1 365 ? 7.517 -4.662 21.259 1.00 20.75 ? 365 VAL A CG2 1 ATOM 2892 N N . ASP A 1 366 ? 8.714 -9.045 22.265 1.00 20.13 ? 366 ASP A N 1 ATOM 2893 C CA . ASP A 1 366 ? 9.046 -10.218 23.047 1.00 20.42 ? 366 ASP A CA 1 ATOM 2894 C C . ASP A 1 366 ? 10.162 -9.801 23.986 1.00 20.67 ? 366 ASP A C 1 ATOM 2895 O O . ASP A 1 366 ? 10.912 -8.905 23.679 1.00 21.24 ? 366 ASP A O 1 ATOM 2896 C CB . ASP A 1 366 ? 9.502 -11.389 22.137 1.00 20.58 ? 366 ASP A CB 1 ATOM 2897 C CG . ASP A 1 366 ? 8.408 -11.877 21.179 1.00 22.67 ? 366 ASP A CG 1 ATOM 2898 O OD1 . ASP A 1 366 ? 7.250 -12.157 21.621 1.00 21.14 ? 366 ASP A OD1 1 ATOM 2899 O OD2 . ASP A 1 366 ? 8.722 -12.025 19.973 1.00 23.33 ? 366 ASP A OD2 1 ATOM 2900 N N . PRO A 1 367 ? 10.246 -10.416 25.169 1.00 21.12 ? 367 PRO A N 1 ATOM 2901 C CA . PRO A 1 367 ? 11.363 -10.123 26.060 1.00 21.77 ? 367 PRO A CA 1 ATOM 2902 C C . PRO A 1 367 ? 12.712 -10.603 25.521 1.00 22.64 ? 367 PRO A C 1 ATOM 2903 O O . PRO A 1 367 ? 13.710 -9.903 25.678 1.00 22.91 ? 367 PRO A O 1 ATOM 2904 C CB . PRO A 1 367 ? 11.024 -10.898 27.333 1.00 21.45 ? 367 PRO A CB 1 ATOM 2905 C CG . PRO A 1 367 ? 9.947 -11.821 26.994 1.00 21.62 ? 367 PRO A CG 1 ATOM 2906 C CD . PRO A 1 367 ? 9.300 -11.388 25.729 1.00 20.26 ? 367 PRO A CD 1 ATOM 2907 N N . ALA A 1 368 ? 12.735 -11.785 24.910 1.00 22.70 ? 368 ALA A N 1 ATOM 2908 C CA . ALA A 1 368 ? 14.000 -12.445 24.614 1.00 23.29 ? 368 ALA A CA 1 ATOM 2909 C C . ALA A 1 368 ? 14.623 -11.813 23.395 1.00 22.78 ? 368 ALA A C 1 ATOM 2910 O O . ALA A 1 368 ? 13.966 -11.610 22.369 1.00 23.35 ? 368 ALA A O 1 ATOM 2911 C CB . ALA A 1 368 ? 13.817 -13.943 24.409 1.00 22.61 ? 368 ALA A CB 1 ATOM 2912 N N . ILE A 1 369 ? 15.902 -11.517 23.536 1.00 22.29 ? 369 ILE A N 1 ATOM 2913 C CA . ILE A 1 369 ? 16.666 -10.757 22.563 1.00 22.47 ? 369 ILE A CA 1 ATOM 2914 C C . ILE A 1 369 ? 17.701 -11.692 21.923 1.00 23.07 ? 369 ILE A C 1 ATOM 2915 O O . ILE A 1 369 ? 18.455 -12.351 22.625 1.00 23.02 ? 369 ILE A O 1 ATOM 2916 C CB . ILE A 1 369 ? 17.404 -9.566 23.256 1.00 21.52 ? 369 ILE A CB 1 ATOM 2917 C CG1 . ILE A 1 369 ? 16.401 -8.651 24.000 1.00 21.80 ? 369 ILE A CG1 1 ATOM 2918 C CG2 . ILE A 1 369 ? 18.207 -8.753 22.231 1.00 21.68 ? 369 ILE A CG2 1 ATOM 2919 C CD1 . ILE A 1 369 ? 15.352 -7.961 23.105 1.00 21.12 ? 369 ILE A CD1 1 ATOM 2920 N N . SER A 1 370 ? 17.707 -11.748 20.595 1.00 24.18 ? 370 SER A N 1 ATOM 2921 C CA . SER A 1 370 ? 18.704 -12.499 19.827 1.00 25.28 ? 370 SER A CA 1 ATOM 2922 C C . SER A 1 370 ? 20.115 -12.148 20.255 1.00 25.22 ? 370 SER A C 1 ATOM 2923 O O . SER A 1 370 ? 20.462 -10.977 20.282 1.00 24.88 ? 370 SER A O 1 ATOM 2924 C CB . SER A 1 370 ? 18.574 -12.162 18.346 1.00 24.45 ? 370 SER A CB 1 ATOM 2925 O OG . SER A 1 370 ? 19.477 -12.953 17.582 1.00 26.96 ? 370 SER A OG 1 ATOM 2926 N N . ASN A 1 371 ? 20.921 -13.147 20.601 1.00 26.46 ? 371 ASN A N 1 ATOM 2927 C CA . ASN A 1 371 ? 22.355 -12.893 20.809 1.00 27.39 ? 371 ASN A CA 1 ATOM 2928 C C . ASN A 1 371 ? 23.189 -13.011 19.528 1.00 28.65 ? 371 ASN A C 1 ATOM 2929 O O . ASN A 1 371 ? 24.419 -13.139 19.603 1.00 28.41 ? 371 ASN A O 1 ATOM 2930 C CB . ASN A 1 371 ? 22.943 -13.801 21.901 1.00 26.72 ? 371 ASN A CB 1 ATOM 2931 C CG . ASN A 1 371 ? 22.970 -15.268 21.507 1.00 27.19 ? 371 ASN A CG 1 ATOM 2932 O OD1 . ASN A 1 371 ? 22.388 -15.685 20.489 1.00 24.41 ? 371 ASN A OD1 1 ATOM 2933 N ND2 . ASN A 1 371 ? 23.615 -16.071 22.340 1.00 27.02 ? 371 ASN A ND2 1 ATOM 2934 N N . ASN A 1 372 ? 22.537 -13.004 18.367 1.00 29.52 ? 372 ASN A N 1 ATOM 2935 C CA . ASN A 1 372 ? 23.277 -13.098 17.097 1.00 31.00 ? 372 ASN A CA 1 ATOM 2936 C C . ASN A 1 372 ? 23.648 -11.706 16.585 1.00 31.73 ? 372 ASN A C 1 ATOM 2937 O O . ASN A 1 372 ? 22.866 -11.056 15.907 1.00 30.96 ? 372 ASN A O 1 ATOM 2938 C CB . ASN A 1 372 ? 22.528 -13.923 16.029 1.00 31.38 ? 372 ASN A CB 1 ATOM 2939 C CG . ASN A 1 372 ? 23.438 -14.331 14.837 1.00 33.11 ? 372 ASN A CG 1 ATOM 2940 O OD1 . ASN A 1 372 ? 24.560 -13.833 14.704 1.00 35.68 ? 372 ASN A OD1 1 ATOM 2941 N ND2 . ASN A 1 372 ? 22.953 -15.238 13.986 1.00 33.97 ? 372 ASN A ND2 1 ATOM 2942 N N . SER A 1 373 ? 24.852 -11.261 16.944 1.00 33.03 ? 373 SER A N 1 ATOM 2943 C CA . SER A 1 373 ? 25.378 -9.962 16.542 1.00 34.41 ? 373 SER A CA 1 ATOM 2944 C C . SER A 1 373 ? 26.876 -10.092 16.312 1.00 35.90 ? 373 SER A C 1 ATOM 2945 O O . SER A 1 373 ? 27.566 -10.756 17.087 1.00 35.95 ? 373 SER A O 1 ATOM 2946 C CB . SER A 1 373 ? 25.148 -8.931 17.641 1.00 34.37 ? 373 SER A CB 1 ATOM 2947 O OG . SER A 1 373 ? 25.564 -7.627 17.254 1.00 33.57 ? 373 SER A OG 1 ATOM 2948 N N . SER A 1 374 ? 27.366 -9.466 15.248 1.00 37.58 ? 374 SER A N 1 ATOM 2949 C CA . SER A 1 374 ? 28.805 -9.437 14.952 1.00 39.98 ? 374 SER A CA 1 ATOM 2950 C C . SER A 1 374 ? 29.209 -8.068 14.409 1.00 40.97 ? 374 SER A C 1 ATOM 2951 O O . SER A 1 374 ? 28.348 -7.212 14.184 1.00 41.67 ? 374 SER A O 1 ATOM 2952 C CB . SER A 1 374 ? 29.188 -10.560 13.971 1.00 39.94 ? 374 SER A CB 1 ATOM 2953 O OG . SER A 1 374 ? 28.334 -10.582 12.837 1.00 41.56 ? 374 SER A OG 1 ATOM 2954 N N . SER A 1 375 ? 30.507 -7.846 14.208 1.00 42.08 ? 375 SER A N 1 ATOM 2955 C CA . SER A 1 375 ? 30.972 -6.608 13.569 1.00 42.59 ? 375 SER A CA 1 ATOM 2956 C C . SER A 1 375 ? 30.330 -6.404 12.197 1.00 42.69 ? 375 SER A C 1 ATOM 2957 O O . SER A 1 375 ? 29.936 -5.287 11.846 1.00 43.63 ? 375 SER A O 1 ATOM 2958 C CB . SER A 1 375 ? 32.506 -6.596 13.437 1.00 43.21 ? 375 SER A CB 1 ATOM 2959 O OG . SER A 1 375 ? 33.136 -6.298 14.680 1.00 44.16 ? 375 SER A OG 1 ATOM 2960 N N . SER A 1 376 ? 30.211 -7.490 11.438 1.00 42.39 ? 376 SER A N 1 ATOM 2961 C CA . SER A 1 376 ? 29.712 -7.446 10.067 1.00 42.32 ? 376 SER A CA 1 ATOM 2962 C C . SER A 1 376 ? 28.186 -7.300 9.967 1.00 41.88 ? 376 SER A C 1 ATOM 2963 O O . SER A 1 376 ? 27.659 -6.975 8.894 1.00 41.84 ? 376 SER A O 1 ATOM 2964 C CB . SER A 1 376 ? 30.167 -8.702 9.317 1.00 42.33 ? 376 SER A CB 1 ATOM 2965 O OG . SER A 1 376 ? 29.274 -9.027 8.258 1.00 44.76 ? 376 SER A OG 1 ATOM 2966 N N . LYS A 1 377 ? 27.484 -7.570 11.074 1.00 40.77 ? 377 LYS A N 1 ATOM 2967 C CA . LYS A 1 377 ? 26.022 -7.567 11.094 1.00 39.60 ? 377 LYS A CA 1 ATOM 2968 C C . LYS A 1 377 ? 25.492 -7.285 12.526 1.00 37.73 ? 377 LYS A C 1 ATOM 2969 O O . LYS A 1 377 ? 24.938 -8.178 13.181 1.00 37.12 ? 377 LYS A O 1 ATOM 2970 C CB . LYS A 1 377 ? 25.513 -8.914 10.568 1.00 40.19 ? 377 LYS A CB 1 ATOM 2971 C CG . LYS A 1 377 ? 24.363 -8.821 9.580 1.00 42.36 ? 377 LYS A CG 1 ATOM 2972 C CD . LYS A 1 377 ? 24.826 -8.563 8.149 1.00 43.35 ? 377 LYS A CD 1 ATOM 2973 C CE . LYS A 1 377 ? 23.679 -8.000 7.293 1.00 45.42 ? 377 LYS A CE 1 ATOM 2974 N NZ . LYS A 1 377 ? 24.066 -7.766 5.870 1.00 45.07 ? 377 LYS A NZ 1 ATOM 2975 N N . PRO A 1 378 ? 25.697 -6.050 13.027 1.00 36.23 ? 378 PRO A N 1 ATOM 2976 C CA . PRO A 1 378 ? 25.336 -5.743 14.412 1.00 34.73 ? 378 PRO A CA 1 ATOM 2977 C C . PRO A 1 378 ? 23.834 -5.865 14.655 1.00 32.92 ? 378 PRO A C 1 ATOM 2978 O O . PRO A 1 378 ? 23.039 -5.550 13.771 1.00 32.74 ? 378 PRO A O 1 ATOM 2979 C CB . PRO A 1 378 ? 25.749 -4.273 14.566 1.00 35.14 ? 378 PRO A CB 1 ATOM 2980 C CG . PRO A 1 378 ? 25.822 -3.736 13.193 1.00 35.21 ? 378 PRO A CG 1 ATOM 2981 C CD . PRO A 1 378 ? 26.282 -4.876 12.350 1.00 36.04 ? 378 PRO A CD 1 ATOM 2982 N N . TYR A 1 379 ? 23.458 -6.334 15.841 1.00 30.97 ? 379 TYR A N 1 ATOM 2983 C CA . TYR A 1 379 ? 22.056 -6.270 16.254 1.00 28.57 ? 379 TYR A CA 1 ATOM 2984 C C . TYR A 1 379 ? 22.039 -5.376 17.455 1.00 27.41 ? 379 TYR A C 1 ATOM 2985 O O . TYR A 1 379 ? 22.408 -5.808 18.549 1.00 28.58 ? 379 TYR A O 1 ATOM 2986 C CB . TYR A 1 379 ? 21.493 -7.659 16.582 1.00 27.92 ? 379 TYR A CB 1 ATOM 2987 C CG . TYR A 1 379 ? 20.040 -7.655 17.052 1.00 26.19 ? 379 TYR A CG 1 ATOM 2988 C CD1 . TYR A 1 379 ? 19.024 -7.070 16.275 1.00 24.89 ? 379 TYR A CD1 1 ATOM 2989 C CD2 . TYR A 1 379 ? 19.678 -8.263 18.246 1.00 25.75 ? 379 TYR A CD2 1 ATOM 2990 C CE1 . TYR A 1 379 ? 17.667 -7.081 16.708 1.00 25.20 ? 379 TYR A CE1 1 ATOM 2991 C CE2 . TYR A 1 379 ? 18.323 -8.289 18.683 1.00 24.88 ? 379 TYR A CE2 1 ATOM 2992 C CZ . TYR A 1 379 ? 17.334 -7.697 17.907 1.00 24.74 ? 379 TYR A CZ 1 ATOM 2993 O OH . TYR A 1 379 ? 16.018 -7.710 18.351 1.00 26.65 ? 379 TYR A OH 1 ATOM 2994 N N . GLY A 1 380 ? 21.674 -4.117 17.224 1.00 25.86 ? 380 GLY A N 1 ATOM 2995 C CA . GLY A 1 380 ? 21.656 -3.063 18.247 1.00 24.85 ? 380 GLY A CA 1 ATOM 2996 C C . GLY A 1 380 ? 21.046 -3.383 19.604 1.00 23.68 ? 380 GLY A C 1 ATOM 2997 O O . GLY A 1 380 ? 21.705 -3.183 20.615 1.00 23.01 ? 380 GLY A O 1 ATOM 2998 N N . PRO A 1 381 ? 19.772 -3.881 19.646 1.00 23.92 ? 381 PRO A N 1 ATOM 2999 C CA . PRO A 1 381 ? 19.172 -4.188 20.961 1.00 23.12 ? 381 PRO A CA 1 ATOM 3000 C C . PRO A 1 381 ? 20.089 -5.067 21.850 1.00 23.07 ? 381 PRO A C 1 ATOM 3001 O O . PRO A 1 381 ? 20.174 -4.849 23.045 1.00 22.27 ? 381 PRO A O 1 ATOM 3002 C CB . PRO A 1 381 ? 17.882 -4.933 20.588 1.00 23.51 ? 381 PRO A CB 1 ATOM 3003 C CG . PRO A 1 381 ? 17.481 -4.340 19.271 1.00 23.66 ? 381 PRO A CG 1 ATOM 3004 C CD . PRO A 1 381 ? 18.834 -4.172 18.548 1.00 23.52 ? 381 PRO A CD 1 ATOM 3005 N N . TYR A 1 382 ? 20.754 -6.053 21.247 1.00 23.24 ? 382 TYR A N 1 ATOM 3006 C CA . TYR A 1 382 ? 21.633 -6.967 21.972 1.00 23.55 ? 382 TYR A CA 1 ATOM 3007 C C . TYR A 1 382 ? 22.933 -6.273 22.379 1.00 23.97 ? 382 TYR A C 1 ATOM 3008 O O . TYR A 1 382 ? 23.408 -6.454 23.507 1.00 25.29 ? 382 TYR A O 1 ATOM 3009 C CB . TYR A 1 382 ? 21.936 -8.224 21.139 1.00 23.46 ? 382 TYR A CB 1 ATOM 3010 C CG . TYR A 1 382 ? 22.971 -9.124 21.791 1.00 23.67 ? 382 TYR A CG 1 ATOM 3011 C CD1 . TYR A 1 382 ? 22.652 -9.847 22.935 1.00 23.32 ? 382 TYR A CD1 1 ATOM 3012 C CD2 . TYR A 1 382 ? 24.288 -9.207 21.295 1.00 22.39 ? 382 TYR A CD2 1 ATOM 3013 C CE1 . TYR A 1 382 ? 23.580 -10.662 23.571 1.00 24.46 ? 382 TYR A CE1 1 ATOM 3014 C CE2 . TYR A 1 382 ? 25.246 -10.028 21.941 1.00 23.17 ? 382 TYR A CE2 1 ATOM 3015 C CZ . TYR A 1 382 ? 24.870 -10.752 23.082 1.00 24.10 ? 382 TYR A CZ 1 ATOM 3016 O OH . TYR A 1 382 ? 25.760 -11.574 23.757 1.00 25.27 ? 382 TYR A OH 1 ATOM 3017 N N . ASP A 1 383 ? 23.509 -5.491 21.466 1.00 24.31 ? 383 ASP A N 1 ATOM 3018 C CA . ASP A 1 383 ? 24.769 -4.794 21.759 1.00 25.43 ? 383 ASP A CA 1 ATOM 3019 C C . ASP A 1 383 ? 24.549 -3.793 22.880 1.00 25.22 ? 383 ASP A C 1 ATOM 3020 O O . ASP A 1 383 ? 25.289 -3.757 23.843 1.00 25.33 ? 383 ASP A O 1 ATOM 3021 C CB . ASP A 1 383 ? 25.286 -4.062 20.515 1.00 25.56 ? 383 ASP A CB 1 ATOM 3022 C CG . ASP A 1 383 ? 25.670 -5.004 19.390 1.00 26.31 ? 383 ASP A CG 1 ATOM 3023 O OD1 . ASP A 1 383 ? 25.804 -6.227 19.613 1.00 25.76 ? 383 ASP A OD1 1 ATOM 3024 O OD2 . ASP A 1 383 ? 25.827 -4.503 18.261 1.00 29.88 ? 383 ASP A OD2 1 ATOM 3025 N N . ARG A 1 384 ? 23.495 -2.994 22.745 1.00 25.25 ? 384 ARG A N 1 ATOM 3026 C CA . ARG A 1 384 ? 23.163 -1.997 23.738 1.00 25.05 ? 384 ARG A CA 1 ATOM 3027 C C . ARG A 1 384 ? 22.869 -2.661 25.064 1.00 24.25 ? 384 ARG A C 1 ATOM 3028 O O . ARG A 1 384 ? 23.211 -2.104 26.094 1.00 23.70 ? 384 ARG A O 1 ATOM 3029 C CB . ARG A 1 384 ? 21.982 -1.108 23.277 1.00 25.10 ? 384 ARG A CB 1 ATOM 3030 C CG . ARG A 1 384 ? 22.347 -0.046 22.216 1.00 25.99 ? 384 ARG A CG 1 ATOM 3031 C CD . ARG A 1 384 ? 21.148 0.818 21.800 1.00 26.63 ? 384 ARG A CD 1 ATOM 3032 N NE . ARG A 1 384 ? 20.186 0.078 20.974 1.00 27.84 ? 384 ARG A NE 1 ATOM 3033 C CZ . ARG A 1 384 ? 20.175 0.043 19.645 1.00 27.44 ? 384 ARG A CZ 1 ATOM 3034 N NH1 . ARG A 1 384 ? 21.064 0.717 18.941 1.00 30.40 ? 384 ARG A NH1 1 ATOM 3035 N NH2 . ARG A 1 384 ? 19.256 -0.668 19.011 1.00 30.26 ? 384 ARG A NH2 1 ATOM 3036 N N . GLY A 1 385 ? 22.224 -3.840 25.050 1.00 23.79 ? 385 GLY A N 1 ATOM 3037 C CA . GLY A 1 385 ? 21.869 -4.543 26.305 1.00 23.57 ? 385 GLY A CA 1 ATOM 3038 C C . GLY A 1 385 ? 23.046 -5.176 27.032 1.00 24.49 ? 385 GLY A C 1 ATOM 3039 O O . GLY A 1 385 ? 23.118 -5.160 28.274 1.00 24.00 ? 385 GLY A O 1 ATOM 3040 N N . SER A 1 386 ? 23.962 -5.744 26.249 1.00 25.40 ? 386 SER A N 1 ATOM 3041 C CA . SER A 1 386 ? 25.227 -6.289 26.767 1.00 26.92 ? 386 SER A CA 1 ATOM 3042 C C . SER A 1 386 ? 26.084 -5.200 27.372 1.00 27.42 ? 386 SER A C 1 ATOM 3043 O O . SER A 1 386 ? 26.535 -5.354 28.478 1.00 28.08 ? 386 SER A O 1 ATOM 3044 C CB . SER A 1 386 ? 25.994 -7.016 25.660 1.00 26.25 ? 386 SER A CB 1 ATOM 3045 O OG . SER A 1 386 ? 25.162 -7.995 25.080 1.00 26.69 ? 386 SER A OG 1 ATOM 3046 N N . ASP A 1 387 ? 26.285 -4.098 26.646 1.00 29.73 ? 387 ASP A N 1 ATOM 3047 C CA . ASP A 1 387 ? 27.005 -2.920 27.160 1.00 31.09 ? 387 ASP A CA 1 ATOM 3048 C C . ASP A 1 387 ? 26.474 -2.520 28.553 1.00 31.77 ? 387 ASP A C 1 ATOM 3049 O O . ASP A 1 387 ? 27.249 -2.254 29.485 1.00 31.32 ? 387 ASP A O 1 ATOM 3050 C CB . ASP A 1 387 ? 26.863 -1.722 26.204 1.00 32.06 ? 387 ASP A CB 1 ATOM 3051 C CG . ASP A 1 387 ? 27.579 -1.910 24.847 1.00 34.47 ? 387 ASP A CG 1 ATOM 3052 O OD1 . ASP A 1 387 ? 28.191 -2.974 24.561 1.00 36.95 ? 387 ASP A OD1 1 ATOM 3053 O OD2 . ASP A 1 387 ? 27.513 -0.953 24.042 1.00 37.56 ? 387 ASP A OD2 1 ATOM 3054 N N . MET A 1 388 ? 25.143 -2.483 28.694 1.00 31.92 ? 388 MET A N 1 ATOM 3055 C CA . MET A 1 388 ? 24.521 -2.099 29.960 1.00 32.47 ? 388 MET A CA 1 ATOM 3056 C C . MET A 1 388 ? 24.478 -3.205 31.013 1.00 30.43 ? 388 MET A C 1 ATOM 3057 O O . MET A 1 388 ? 24.232 -2.941 32.186 1.00 30.59 ? 388 MET A O 1 ATOM 3058 C CB . MET A 1 388 ? 23.132 -1.493 29.723 1.00 32.39 ? 388 MET A CB 1 ATOM 3059 C CG . MET A 1 388 ? 23.196 -0.075 29.145 1.00 34.59 ? 388 MET A CG 1 ATOM 3060 S SD . MET A 1 388 ? 21.572 0.643 28.827 1.00 38.37 ? 388 MET A SD 1 ATOM 3061 C CE . MET A 1 388 ? 20.978 0.823 30.505 1.00 35.42 ? 388 MET A CE 1 ATOM 3062 N N . LYS A 1 389 ? 24.733 -4.441 30.594 1.00 28.84 ? 389 LYS A N 1 ATOM 3063 C CA . LYS A 1 389 ? 24.767 -5.606 31.511 1.00 27.51 ? 389 LYS A CA 1 ATOM 3064 C C . LYS A 1 389 ? 23.415 -5.915 32.207 1.00 25.76 ? 389 LYS A C 1 ATOM 3065 O O . LYS A 1 389 ? 23.345 -6.218 33.406 1.00 24.53 ? 389 LYS A O 1 ATOM 3066 C CB . LYS A 1 389 ? 25.932 -5.496 32.507 1.00 27.96 ? 389 LYS A CB 1 ATOM 3067 C CG . LYS A 1 389 ? 27.271 -5.160 31.825 1.00 29.31 ? 389 LYS A CG 1 ATOM 3068 C CD . LYS A 1 389 ? 28.370 -6.126 32.210 1.00 32.49 ? 389 LYS A CD 1 ATOM 3069 C CE . LYS A 1 389 ? 29.553 -6.042 31.238 1.00 35.43 ? 389 LYS A CE 1 ATOM 3070 N NZ . LYS A 1 389 ? 30.414 -7.275 31.266 1.00 35.12 ? 389 LYS A NZ 1 ATOM 3071 N N . ILE A 1 390 ? 22.354 -5.866 31.424 1.00 24.15 ? 390 ILE A N 1 ATOM 3072 C CA . ILE A 1 390 ? 21.002 -5.965 31.977 1.00 23.08 ? 390 ILE A CA 1 ATOM 3073 C C . ILE A 1 390 ? 20.318 -7.302 31.691 1.00 22.94 ? 390 ILE A C 1 ATOM 3074 O O . ILE A 1 390 ? 19.097 -7.387 31.789 1.00 21.77 ? 390 ILE A O 1 ATOM 3075 C CB . ILE A 1 390 ? 20.096 -4.797 31.479 1.00 22.99 ? 390 ILE A CB 1 ATOM 3076 C CG1 . ILE A 1 390 ? 20.243 -4.567 29.973 1.00 23.54 ? 390 ILE A CG1 1 ATOM 3077 C CG2 . ILE A 1 390 ? 20.378 -3.532 32.257 1.00 23.18 ? 390 ILE A CG2 1 ATOM 3078 C CD1 . ILE A 1 390 ? 19.512 -5.541 29.074 1.00 20.98 ? 390 ILE A CD1 1 ATOM 3079 N N . TRP A 1 391 ? 21.093 -8.336 31.327 1.00 22.21 ? 391 TRP A N 1 ATOM 3080 C CA . TRP A 1 391 ? 20.519 -9.680 31.108 1.00 21.68 ? 391 TRP A CA 1 ATOM 3081 C C . TRP A 1 391 ? 20.367 -10.502 32.412 1.00 21.06 ? 391 TRP A C 1 ATOM 3082 O O . TRP A 1 391 ? 21.050 -10.237 33.411 1.00 21.51 ? 391 TRP A O 1 ATOM 3083 C CB . TRP A 1 391 ? 21.324 -10.474 30.067 1.00 20.84 ? 391 TRP A CB 1 ATOM 3084 C CG . TRP A 1 391 ? 21.734 -9.724 28.828 1.00 20.12 ? 391 TRP A CG 1 ATOM 3085 C CD1 . TRP A 1 391 ? 23.024 -9.530 28.380 1.00 19.87 ? 391 TRP A CD1 1 ATOM 3086 C CD2 . TRP A 1 391 ? 20.876 -9.109 27.851 1.00 18.74 ? 391 TRP A CD2 1 ATOM 3087 N NE1 . TRP A 1 391 ? 23.010 -8.833 27.195 1.00 20.76 ? 391 TRP A NE1 1 ATOM 3088 C CE2 . TRP A 1 391 ? 21.711 -8.565 26.845 1.00 17.55 ? 391 TRP A CE2 1 ATOM 3089 C CE3 . TRP A 1 391 ? 19.486 -8.981 27.719 1.00 18.79 ? 391 TRP A CE3 1 ATOM 3090 C CZ2 . TRP A 1 391 ? 21.202 -7.875 25.739 1.00 20.97 ? 391 TRP A CZ2 1 ATOM 3091 C CZ3 . TRP A 1 391 ? 18.975 -8.298 26.607 1.00 20.40 ? 391 TRP A CZ3 1 ATOM 3092 C CH2 . TRP A 1 391 ? 19.820 -7.762 25.633 1.00 21.38 ? 391 TRP A CH2 1 ATOM 3093 N N . VAL A 1 392 ? 19.458 -11.479 32.385 1.00 20.50 ? 392 VAL A N 1 ATOM 3094 C CA . VAL A 1 392 ? 19.341 -12.500 33.426 1.00 19.43 ? 392 VAL A CA 1 ATOM 3095 C C . VAL A 1 392 ? 20.586 -13.366 33.339 1.00 20.26 ? 392 VAL A C 1 ATOM 3096 O O . VAL A 1 392 ? 20.933 -13.851 32.265 1.00 19.76 ? 392 VAL A O 1 ATOM 3097 C CB . VAL A 1 392 ? 18.113 -13.444 33.231 1.00 19.02 ? 392 VAL A CB 1 ATOM 3098 C CG1 . VAL A 1 392 ? 18.122 -14.547 34.295 1.00 15.42 ? 392 VAL A CG1 1 ATOM 3099 C CG2 . VAL A 1 392 ? 16.769 -12.652 33.228 1.00 16.39 ? 392 VAL A CG2 1 ATOM 3100 N N . ASN A 1 393 ? 21.239 -13.570 34.470 1.00 22.25 ? 393 ASN A N 1 ATOM 3101 C CA . ASN A 1 393 ? 22.481 -14.350 34.502 1.00 23.34 ? 393 ASN A CA 1 ATOM 3102 C C . ASN A 1 393 ? 22.190 -15.785 34.909 1.00 24.45 ? 393 ASN A C 1 ATOM 3103 O O . ASN A 1 393 ? 21.186 -16.070 35.583 1.00 24.31 ? 393 ASN A O 1 ATOM 3104 C CB . ASN A 1 393 ? 23.506 -13.700 35.457 1.00 23.77 ? 393 ASN A CB 1 ATOM 3105 C CG . ASN A 1 393 ? 24.007 -12.336 34.960 1.00 23.48 ? 393 ASN A CG 1 ATOM 3106 O OD1 . ASN A 1 393 ? 23.899 -12.012 33.776 1.00 22.95 ? 393 ASN A OD1 1 ATOM 3107 N ND2 . ASN A 1 393 ? 24.556 -11.535 35.885 1.00 25.12 ? 393 ASN A ND2 1 ATOM 3108 N N . SER A 1 394 ? 23.049 -16.695 34.456 1.00 25.53 ? 394 SER A N 1 ATOM 3109 C CA . SER A 1 394 ? 23.117 -18.050 34.994 1.00 26.61 ? 394 SER A CA 1 ATOM 3110 C C . SER A 1 394 ? 23.531 -17.969 36.454 1.00 26.42 ? 394 SER A C 1 ATOM 3111 O O . SER A 1 394 ? 23.905 -16.898 36.935 1.00 26.46 ? 394 SER A O 1 ATOM 3112 C CB . SER A 1 394 ? 24.135 -18.888 34.210 1.00 26.88 ? 394 SER A CB 1 ATOM 3113 O OG . SER A 1 394 ? 23.723 -19.030 32.862 1.00 30.60 ? 394 SER A OG 1 ATOM 3114 N N . SER A 1 395 ? 23.475 -19.098 37.153 1.00 27.19 ? 395 SER A N 1 ATOM 3115 C CA . SER A 1 395 ? 23.721 -19.130 38.599 1.00 28.88 ? 395 SER A CA 1 ATOM 3116 C C . SER A 1 395 ? 25.120 -18.684 39.050 1.00 29.44 ? 395 SER A C 1 ATOM 3117 O O . SER A 1 395 ? 25.308 -18.392 40.229 1.00 30.45 ? 395 SER A O 1 ATOM 3118 C CB . SER A 1 395 ? 23.437 -20.525 39.147 1.00 28.68 ? 395 SER A CB 1 ATOM 3119 O OG . SER A 1 395 ? 24.445 -21.426 38.717 1.00 30.67 ? 395 SER A OG 1 ATOM 3120 N N . ASP A 1 396 ? 26.094 -18.622 38.138 1.00 30.13 ? 396 ASP A N 1 ATOM 3121 C CA . ASP A 1 396 ? 27.439 -18.104 38.503 1.00 30.42 ? 396 ASP A CA 1 ATOM 3122 C C . ASP A 1 396 ? 27.393 -16.599 38.813 1.00 30.32 ? 396 ASP A C 1 ATOM 3123 O O . ASP A 1 396 ? 28.345 -16.016 39.346 1.00 29.69 ? 396 ASP A O 1 ATOM 3124 C CB . ASP A 1 396 ? 28.497 -18.441 37.437 1.00 30.57 ? 396 ASP A CB 1 ATOM 3125 C CG . ASP A 1 396 ? 28.255 -17.756 36.102 1.00 32.19 ? 396 ASP A CG 1 ATOM 3126 O OD1 . ASP A 1 396 ? 27.309 -16.928 35.985 1.00 34.53 ? 396 ASP A OD1 1 ATOM 3127 O OD2 . ASP A 1 396 ? 29.030 -18.045 35.153 1.00 32.32 ? 396 ASP A OD2 1 ATOM 3128 N N . GLY A 1 397 ? 26.251 -15.993 38.471 1.00 30.01 ? 397 GLY A N 1 ATOM 3129 C CA . GLY A 1 397 ? 25.989 -14.591 38.725 1.00 28.87 ? 397 GLY A CA 1 ATOM 3130 C C . GLY A 1 397 ? 26.662 -13.603 37.795 1.00 28.26 ? 397 GLY A C 1 ATOM 3131 O O . GLY A 1 397 ? 26.571 -12.411 38.025 1.00 28.36 ? 397 GLY A O 1 ATOM 3132 N N . VAL A 1 398 ? 27.337 -14.073 36.748 1.00 28.12 ? 398 VAL A N 1 ATOM 3133 C CA . VAL A 1 398 ? 28.079 -13.149 35.858 1.00 28.06 ? 398 VAL A CA 1 ATOM 3134 C C . VAL A 1 398 ? 27.904 -13.404 34.352 1.00 27.21 ? 398 VAL A C 1 ATOM 3135 O O . VAL A 1 398 ? 28.111 -12.514 33.524 1.00 27.39 ? 398 VAL A O 1 ATOM 3136 C CB . VAL A 1 398 ? 29.605 -13.027 36.237 1.00 28.96 ? 398 VAL A CB 1 ATOM 3137 C CG1 . VAL A 1 398 ? 29.775 -12.179 37.485 1.00 29.27 ? 398 VAL A CG1 1 ATOM 3138 C CG2 . VAL A 1 398 ? 30.238 -14.400 36.443 1.00 29.06 ? 398 VAL A CG2 1 ATOM 3139 N N . THR A 1 399 ? 27.488 -14.610 34.008 1.00 26.63 ? 399 THR A N 1 ATOM 3140 C CA . THR A 1 399 ? 27.343 -14.997 32.624 1.00 26.99 ? 399 THR A CA 1 ATOM 3141 C C . THR A 1 399 ? 25.854 -14.983 32.209 1.00 25.82 ? 399 THR A C 1 ATOM 3142 O O . THR A 1 399 ? 25.071 -15.736 32.763 1.00 25.24 ? 399 THR A O 1 ATOM 3143 C CB . THR A 1 399 ? 27.940 -16.415 32.397 1.00 26.87 ? 399 THR A CB 1 ATOM 3144 O OG1 . THR A 1 399 ? 29.276 -16.467 32.938 1.00 28.99 ? 399 THR A OG1 1 ATOM 3145 C CG2 . THR A 1 399 ? 27.973 -16.760 30.924 1.00 27.72 ? 399 THR A CG2 1 ATOM 3146 N N . PRO A 1 400 ? 25.487 -14.158 31.206 1.00 25.54 ? 400 PRO A N 1 ATOM 3147 C CA . PRO A 1 400 ? 24.087 -14.103 30.754 1.00 25.06 ? 400 PRO A CA 1 ATOM 3148 C C . PRO A 1 400 ? 23.540 -15.496 30.404 1.00 24.75 ? 400 PRO A C 1 ATOM 3149 O O . PRO A 1 400 ? 24.234 -16.292 29.765 1.00 24.55 ? 400 PRO A O 1 ATOM 3150 C CB . PRO A 1 400 ? 24.154 -13.223 29.493 1.00 25.68 ? 400 PRO A CB 1 ATOM 3151 C CG . PRO A 1 400 ? 25.339 -12.383 29.660 1.00 26.39 ? 400 PRO A CG 1 ATOM 3152 C CD . PRO A 1 400 ? 26.347 -13.234 30.437 1.00 25.01 ? 400 PRO A CD 1 ATOM 3153 N N . LEU A 1 401 ? 22.321 -15.804 30.845 1.00 22.91 ? 401 LEU A N 1 ATOM 3154 C CA . LEU A 1 401 ? 21.736 -17.099 30.559 1.00 21.66 ? 401 LEU A CA 1 ATOM 3155 C C . LEU A 1 401 ? 21.257 -17.138 29.103 1.00 21.51 ? 401 LEU A C 1 ATOM 3156 O O . LEU A 1 401 ? 20.651 -16.180 28.611 1.00 20.88 ? 401 LEU A O 1 ATOM 3157 C CB . LEU A 1 401 ? 20.592 -17.398 31.546 1.00 21.91 ? 401 LEU A CB 1 ATOM 3158 C CG . LEU A 1 401 ? 19.954 -18.782 31.476 1.00 21.19 ? 401 LEU A CG 1 ATOM 3159 C CD1 . LEU A 1 401 ? 19.411 -19.153 32.819 1.00 18.91 ? 401 LEU A CD1 1 ATOM 3160 C CD2 . LEU A 1 401 ? 18.850 -18.799 30.403 1.00 21.02 ? 401 LEU A CD2 1 ATOM 3161 N N . ILE A 1 402 ? 21.529 -18.247 28.422 1.00 21.49 ? 402 ILE A N 1 ATOM 3162 C CA . ILE A 1 402 ? 21.241 -18.366 27.011 1.00 22.12 ? 402 ILE A CA 1 ATOM 3163 C C . ILE A 1 402 ? 20.102 -19.361 26.852 1.00 21.79 ? 402 ILE A C 1 ATOM 3164 O O . ILE A 1 402 ? 20.179 -20.483 27.333 1.00 20.94 ? 402 ILE A O 1 ATOM 3165 C CB . ILE A 1 402 ? 22.476 -18.865 26.168 1.00 22.93 ? 402 ILE A CB 1 ATOM 3166 C CG1 . ILE A 1 402 ? 23.730 -17.988 26.365 1.00 24.40 ? 402 ILE A CG1 1 ATOM 3167 C CG2 . ILE A 1 402 ? 22.095 -19.010 24.679 1.00 22.46 ? 402 ILE A CG2 1 ATOM 3168 C CD1 . ILE A 1 402 ? 23.557 -16.497 26.149 1.00 25.62 ? 402 ILE A CD1 1 ATOM 3169 N N . GLY A 1 403 ? 19.032 -18.926 26.192 1.00 21.79 ? 403 GLY A N 1 ATOM 3170 C CA . GLY A 1 403 ? 17.906 -19.810 25.922 1.00 22.09 ? 403 GLY A CA 1 ATOM 3171 C C . GLY A 1 403 ? 17.609 -19.791 24.441 1.00 22.36 ? 403 GLY A C 1 ATOM 3172 O O . GLY A 1 403 ? 18.472 -19.481 23.627 1.00 22.54 ? 403 GLY A O 1 ATOM 3173 N N . GLU A 1 404 ? 16.386 -20.141 24.082 1.00 22.76 ? 404 GLU A N 1 ATOM 3174 C CA . GLU A 1 404 ? 16.002 -20.145 22.701 1.00 23.05 ? 404 GLU A CA 1 ATOM 3175 C C . GLU A 1 404 ? 14.551 -19.697 22.588 1.00 22.36 ? 404 GLU A C 1 ATOM 3176 O O . GLU A 1 404 ? 13.675 -20.312 23.188 1.00 22.71 ? 404 GLU A O 1 ATOM 3177 C CB . GLU A 1 404 ? 16.152 -21.562 22.123 1.00 23.54 ? 404 GLU A CB 1 ATOM 3178 C CG . GLU A 1 404 ? 15.915 -21.626 20.608 1.00 28.35 ? 404 GLU A CG 1 ATOM 3179 C CD . GLU A 1 404 ? 15.577 -23.009 20.104 1.00 36.03 ? 404 GLU A CD 1 ATOM 3180 O OE1 . GLU A 1 404 ? 16.032 -24.000 20.735 1.00 39.28 ? 404 GLU A OE1 1 ATOM 3181 O OE2 . GLU A 1 404 ? 14.864 -23.100 19.065 1.00 38.67 ? 404 GLU A OE2 1 ATOM 3182 N N . VAL A 1 405 ? 14.288 -18.647 21.823 1.00 21.24 ? 405 VAL A N 1 ATOM 3183 C CA . VAL A 1 405 ? 12.881 -18.301 21.486 1.00 20.90 ? 405 VAL A CA 1 ATOM 3184 C C . VAL A 1 405 ? 12.795 -18.096 19.969 1.00 21.46 ? 405 VAL A C 1 ATOM 3185 O O . VAL A 1 405 ? 13.536 -18.748 19.246 1.00 21.54 ? 405 VAL A O 1 ATOM 3186 C CB . VAL A 1 405 ? 12.262 -17.159 22.368 1.00 20.07 ? 405 VAL A CB 1 ATOM 3187 C CG1 . VAL A 1 405 ? 10.704 -17.300 22.415 1.00 18.51 ? 405 VAL A CG1 1 ATOM 3188 C CG2 . VAL A 1 405 ? 12.767 -17.278 23.799 1.00 18.94 ? 405 VAL A CG2 1 ATOM 3189 N N . TRP A 1 406 ? 11.919 -17.212 19.495 1.00 21.08 ? 406 TRP A N 1 ATOM 3190 C CA . TRP A 1 406 ? 11.631 -17.034 18.071 1.00 21.88 ? 406 TRP A CA 1 ATOM 3191 C C . TRP A 1 406 ? 12.871 -16.855 17.154 1.00 22.43 ? 406 TRP A C 1 ATOM 3192 O O . TRP A 1 406 ? 12.949 -17.468 16.096 1.00 22.58 ? 406 TRP A O 1 ATOM 3193 C CB . TRP A 1 406 ? 10.665 -15.855 17.880 1.00 22.04 ? 406 TRP A CB 1 ATOM 3194 C CG . TRP A 1 406 ? 9.341 -16.013 18.581 1.00 20.99 ? 406 TRP A CG 1 ATOM 3195 C CD1 . TRP A 1 406 ? 8.804 -15.193 19.533 1.00 22.60 ? 406 TRP A CD1 1 ATOM 3196 C CD2 . TRP A 1 406 ? 8.393 -17.065 18.374 1.00 21.55 ? 406 TRP A CD2 1 ATOM 3197 N NE1 . TRP A 1 406 ? 7.567 -15.678 19.935 1.00 21.24 ? 406 TRP A NE1 1 ATOM 3198 C CE2 . TRP A 1 406 ? 7.288 -16.815 19.226 1.00 20.56 ? 406 TRP A CE2 1 ATOM 3199 C CE3 . TRP A 1 406 ? 8.354 -18.185 17.528 1.00 22.20 ? 406 TRP A CE3 1 ATOM 3200 C CZ2 . TRP A 1 406 ? 6.174 -17.652 19.270 1.00 21.25 ? 406 TRP A CZ2 1 ATOM 3201 C CZ3 . TRP A 1 406 ? 7.237 -19.024 17.579 1.00 22.60 ? 406 TRP A CZ3 1 ATOM 3202 C CH2 . TRP A 1 406 ? 6.170 -18.751 18.454 1.00 21.29 ? 406 TRP A CH2 1 ATOM 3203 N N . PRO A 1 407 ? 13.822 -16.004 17.545 1.00 22.61 ? 407 PRO A N 1 ATOM 3204 C CA . PRO A 1 407 ? 14.880 -15.755 16.590 1.00 23.68 ? 407 PRO A CA 1 ATOM 3205 C C . PRO A 1 407 ? 16.052 -16.761 16.667 1.00 24.60 ? 407 PRO A C 1 ATOM 3206 O O . PRO A 1 407 ? 17.074 -16.570 15.998 1.00 26.18 ? 407 PRO A O 1 ATOM 3207 C CB . PRO A 1 407 ? 15.344 -14.341 16.967 1.00 23.27 ? 407 PRO A CB 1 ATOM 3208 C CG . PRO A 1 407 ? 14.801 -14.057 18.324 1.00 21.52 ? 407 PRO A CG 1 ATOM 3209 C CD . PRO A 1 407 ? 14.030 -15.239 18.787 1.00 22.92 ? 407 PRO A CD 1 ATOM 3210 N N . GLY A 1 408 ? 15.905 -17.811 17.471 1.00 24.17 ? 408 GLY A N 1 ATOM 3211 C CA . GLY A 1 408 ? 17.011 -18.720 17.774 1.00 23.35 ? 408 GLY A CA 1 ATOM 3212 C C . GLY A 1 408 ? 17.496 -18.459 19.188 1.00 22.67 ? 408 GLY A C 1 ATOM 3213 O O . GLY A 1 408 ? 16.699 -18.111 20.060 1.00 22.18 ? 408 GLY A O 1 ATOM 3214 N N . GLN A 1 409 ? 18.797 -18.615 19.417 1.00 21.58 ? 409 GLN A N 1 ATOM 3215 C CA . GLN A 1 409 ? 19.404 -18.359 20.727 1.00 20.71 ? 409 GLN A CA 1 ATOM 3216 C C . GLN A 1 409 ? 19.196 -16.937 21.191 1.00 20.18 ? 409 GLN A C 1 ATOM 3217 O O . GLN A 1 409 ? 19.219 -16.005 20.400 1.00 20.19 ? 409 GLN A O 1 ATOM 3218 C CB . GLN A 1 409 ? 20.906 -18.646 20.695 1.00 21.21 ? 409 GLN A CB 1 ATOM 3219 C CG . GLN A 1 409 ? 21.247 -20.078 20.917 1.00 24.08 ? 409 GLN A CG 1 ATOM 3220 C CD . GLN A 1 409 ? 22.735 -20.282 21.171 1.00 27.03 ? 409 GLN A CD 1 ATOM 3221 O OE1 . GLN A 1 409 ? 23.503 -19.319 21.279 1.00 30.10 ? 409 GLN A OE1 1 ATOM 3222 N NE2 . GLN A 1 409 ? 23.141 -21.539 21.294 1.00 27.13 ? 409 GLN A NE2 1 ATOM 3223 N N . THR A 1 410 ? 19.014 -16.762 22.489 1.00 20.52 ? 410 THR A N 1 ATOM 3224 C CA . THR A 1 410 ? 18.628 -15.451 23.011 1.00 20.47 ? 410 THR A CA 1 ATOM 3225 C C . THR A 1 410 ? 19.092 -15.289 24.414 1.00 19.21 ? 410 THR A C 1 ATOM 3226 O O . THR A 1 410 ? 19.216 -16.252 25.136 1.00 20.14 ? 410 THR A O 1 ATOM 3227 C CB . THR A 1 410 ? 17.075 -15.301 23.130 1.00 20.44 ? 410 THR A CB 1 ATOM 3228 O OG1 . THR A 1 410 ? 16.556 -16.392 23.900 1.00 22.58 ? 410 THR A OG1 1 ATOM 3229 C CG2 . THR A 1 410 ? 16.407 -15.251 21.805 1.00 20.54 ? 410 THR A CG2 1 ATOM 3230 N N . VAL A 1 411 ? 19.279 -14.042 24.804 1.00 19.20 ? 411 VAL A N 1 ATOM 3231 C CA . VAL A 1 411 ? 19.406 -13.641 26.192 1.00 19.00 ? 411 VAL A CA 1 ATOM 3232 C C . VAL A 1 411 ? 18.054 -13.024 26.667 1.00 18.97 ? 411 VAL A C 1 ATOM 3233 O O . VAL A 1 411 ? 17.209 -12.698 25.863 1.00 19.66 ? 411 VAL A O 1 ATOM 3234 C CB . VAL A 1 411 ? 20.545 -12.613 26.334 1.00 18.81 ? 411 VAL A CB 1 ATOM 3235 C CG1 . VAL A 1 411 ? 21.927 -13.314 26.295 1.00 20.20 ? 411 VAL A CG1 1 ATOM 3236 C CG2 . VAL A 1 411 ? 20.448 -11.610 25.230 1.00 19.13 ? 411 VAL A CG2 1 ATOM 3237 N N . PHE A 1 412 ? 17.876 -12.852 27.969 1.00 19.65 ? 412 PHE A N 1 ATOM 3238 C CA . PHE A 1 412 ? 16.585 -12.435 28.540 1.00 19.51 ? 412 PHE A CA 1 ATOM 3239 C C . PHE A 1 412 ? 16.815 -11.183 29.383 1.00 19.13 ? 412 PHE A C 1 ATOM 3240 O O . PHE A 1 412 ? 17.676 -11.200 30.259 1.00 19.98 ? 412 PHE A O 1 ATOM 3241 C CB . PHE A 1 412 ? 16.007 -13.576 29.412 1.00 18.97 ? 412 PHE A CB 1 ATOM 3242 C CG . PHE A 1 412 ? 15.728 -14.841 28.647 1.00 18.07 ? 412 PHE A CG 1 ATOM 3243 C CD1 . PHE A 1 412 ? 14.489 -15.056 28.069 1.00 19.18 ? 412 PHE A CD1 1 ATOM 3244 C CD2 . PHE A 1 412 ? 16.723 -15.815 28.482 1.00 17.81 ? 412 PHE A CD2 1 ATOM 3245 C CE1 . PHE A 1 412 ? 14.227 -16.230 27.345 1.00 18.26 ? 412 PHE A CE1 1 ATOM 3246 C CE2 . PHE A 1 412 ? 16.465 -16.972 27.762 1.00 16.74 ? 412 PHE A CE2 1 ATOM 3247 C CZ . PHE A 1 412 ? 15.210 -17.176 27.195 1.00 20.23 ? 412 PHE A CZ 1 ATOM 3248 N N . PRO A 1 413 ? 16.066 -10.089 29.122 1.00 18.66 ? 413 PRO A N 1 ATOM 3249 C CA . PRO A 1 413 ? 16.259 -8.900 29.946 1.00 18.91 ? 413 PRO A CA 1 ATOM 3250 C C . PRO A 1 413 ? 15.879 -9.164 31.372 1.00 19.17 ? 413 PRO A C 1 ATOM 3251 O O . PRO A 1 413 ? 14.906 -9.888 31.622 1.00 18.76 ? 413 PRO A O 1 ATOM 3252 C CB . PRO A 1 413 ? 15.299 -7.870 29.324 1.00 18.23 ? 413 PRO A CB 1 ATOM 3253 C CG . PRO A 1 413 ? 15.111 -8.356 27.922 1.00 17.76 ? 413 PRO A CG 1 ATOM 3254 C CD . PRO A 1 413 ? 15.084 -9.843 28.055 1.00 18.34 ? 413 PRO A CD 1 ATOM 3255 N N . ASP A 1 414 ? 16.646 -8.590 32.297 1.00 18.84 ? 414 ASP A N 1 ATOM 3256 C CA . ASP A 1 414 ? 16.272 -8.594 33.704 1.00 19.52 ? 414 ASP A CA 1 ATOM 3257 C C . ASP A 1 414 ? 15.513 -7.305 34.032 1.00 19.84 ? 414 ASP A C 1 ATOM 3258 O O . ASP A 1 414 ? 16.092 -6.260 34.323 1.00 18.54 ? 414 ASP A O 1 ATOM 3259 C CB . ASP A 1 414 ? 17.473 -8.816 34.643 1.00 19.78 ? 414 ASP A CB 1 ATOM 3260 C CG . ASP A 1 414 ? 17.144 -8.550 36.115 1.00 20.29 ? 414 ASP A CG 1 ATOM 3261 O OD1 . ASP A 1 414 ? 15.960 -8.707 36.539 1.00 22.71 ? 414 ASP A OD1 1 ATOM 3262 O OD2 . ASP A 1 414 ? 18.076 -8.215 36.884 1.00 19.83 ? 414 ASP A OD2 1 ATOM 3263 N N . TYR A 1 415 ? 14.191 -7.389 33.978 1.00 20.01 ? 415 TYR A N 1 ATOM 3264 C CA . TYR A 1 415 ? 13.381 -6.175 34.107 1.00 19.62 ? 415 TYR A CA 1 ATOM 3265 C C . TYR A 1 415 ? 13.290 -5.713 35.546 1.00 20.84 ? 415 TYR A C 1 ATOM 3266 O O . TYR A 1 415 ? 12.793 -4.623 35.812 1.00 21.55 ? 415 TYR A O 1 ATOM 3267 C CB . TYR A 1 415 ? 11.981 -6.362 33.498 1.00 19.21 ? 415 TYR A CB 1 ATOM 3268 C CG . TYR A 1 415 ? 11.952 -6.535 32.002 1.00 16.10 ? 415 TYR A CG 1 ATOM 3269 C CD1 . TYR A 1 415 ? 12.126 -5.457 31.143 1.00 15.91 ? 415 TYR A CD1 1 ATOM 3270 C CD2 . TYR A 1 415 ? 11.688 -7.769 31.443 1.00 13.86 ? 415 TYR A CD2 1 ATOM 3271 C CE1 . TYR A 1 415 ? 12.076 -5.630 29.781 1.00 13.05 ? 415 TYR A CE1 1 ATOM 3272 C CE2 . TYR A 1 415 ? 11.662 -7.943 30.081 1.00 15.54 ? 415 TYR A CE2 1 ATOM 3273 C CZ . TYR A 1 415 ? 11.865 -6.871 29.260 1.00 16.89 ? 415 TYR A CZ 1 ATOM 3274 O OH . TYR A 1 415 ? 11.789 -7.056 27.902 1.00 19.31 ? 415 TYR A OH 1 ATOM 3275 N N . THR A 1 416 ? 13.807 -6.512 36.480 1.00 22.24 ? 416 THR A N 1 ATOM 3276 C CA . THR A 1 416 ? 13.872 -6.107 37.885 1.00 22.81 ? 416 THR A CA 1 ATOM 3277 C C . THR A 1 416 ? 14.985 -5.106 38.162 1.00 23.93 ? 416 THR A C 1 ATOM 3278 O O . THR A 1 416 ? 14.920 -4.377 39.139 1.00 23.65 ? 416 THR A O 1 ATOM 3279 C CB . THR A 1 416 ? 13.983 -7.316 38.872 1.00 23.50 ? 416 THR A CB 1 ATOM 3280 O OG1 . THR A 1 416 ? 15.331 -7.829 38.913 1.00 23.93 ? 416 THR A OG1 1 ATOM 3281 C CG2 . THR A 1 416 ? 13.010 -8.386 38.501 1.00 22.14 ? 416 THR A CG2 1 ATOM 3282 N N . ASN A 1 417 ? 16.006 -5.087 37.302 1.00 24.82 ? 417 ASN A N 1 ATOM 3283 C CA . ASN A 1 417 ? 17.034 -4.064 37.311 1.00 25.46 ? 417 ASN A CA 1 ATOM 3284 C C . ASN A 1 417 ? 16.494 -2.720 36.768 1.00 26.55 ? 417 ASN A C 1 ATOM 3285 O O . ASN A 1 417 ? 16.074 -2.657 35.621 1.00 26.29 ? 417 ASN A O 1 ATOM 3286 C CB . ASN A 1 417 ? 18.187 -4.551 36.426 1.00 25.61 ? 417 ASN A CB 1 ATOM 3287 C CG . ASN A 1 417 ? 19.433 -3.698 36.542 1.00 24.36 ? 417 ASN A CG 1 ATOM 3288 O OD1 . ASN A 1 417 ? 19.366 -2.518 36.868 1.00 23.41 ? 417 ASN A OD1 1 ATOM 3289 N ND2 . ASN A 1 417 ? 20.587 -4.304 36.263 1.00 21.74 ? 417 ASN A ND2 1 ATOM 3290 N N . PRO A 1 418 ? 16.520 -1.636 37.584 1.00 27.99 ? 418 PRO A N 1 ATOM 3291 C CA . PRO A 1 418 ? 16.108 -0.297 37.095 1.00 28.63 ? 418 PRO A CA 1 ATOM 3292 C C . PRO A 1 418 ? 16.764 0.107 35.766 1.00 29.20 ? 418 PRO A C 1 ATOM 3293 O O . PRO A 1 418 ? 16.116 0.715 34.916 1.00 29.14 ? 418 PRO A O 1 ATOM 3294 C CB . PRO A 1 418 ? 16.590 0.652 38.207 1.00 29.08 ? 418 PRO A CB 1 ATOM 3295 C CG . PRO A 1 418 ? 16.672 -0.184 39.429 1.00 28.85 ? 418 PRO A CG 1 ATOM 3296 C CD . PRO A 1 418 ? 16.941 -1.603 38.998 1.00 28.06 ? 418 PRO A CD 1 ATOM 3297 N N . ASN A 1 419 ? 18.043 -0.239 35.603 1.00 29.38 ? 419 ASN A N 1 ATOM 3298 C CA . ASN A 1 419 ? 18.790 0.041 34.388 1.00 29.83 ? 419 ASN A CA 1 ATOM 3299 C C . ASN A 1 419 ? 18.220 -0.645 33.155 1.00 28.75 ? 419 ASN A C 1 ATOM 3300 O O . ASN A 1 419 ? 18.385 -0.162 32.033 1.00 28.37 ? 419 ASN A O 1 ATOM 3301 C CB . ASN A 1 419 ? 20.238 -0.418 34.566 1.00 30.94 ? 419 ASN A CB 1 ATOM 3302 C CG . ASN A 1 419 ? 21.202 0.730 34.588 1.00 34.65 ? 419 ASN A CG 1 ATOM 3303 O OD1 . ASN A 1 419 ? 21.351 1.444 33.590 1.00 38.44 ? 419 ASN A OD1 1 ATOM 3304 N ND2 . ASN A 1 419 ? 21.858 0.931 35.729 1.00 37.39 ? 419 ASN A ND2 1 ATOM 3305 N N . CYS A 1 420 ? 17.581 -1.791 33.359 1.00 27.55 ? 420 CYS A N 1 ATOM 3306 C CA . CYS A 1 420 ? 17.024 -2.532 32.237 1.00 27.24 ? 420 CYS A CA 1 ATOM 3307 C C . CYS A 1 420 ? 15.903 -1.715 31.614 1.00 26.95 ? 420 CYS A C 1 ATOM 3308 O O . CYS A 1 420 ? 15.820 -1.631 30.398 1.00 27.62 ? 420 CYS A O 1 ATOM 3309 C CB . CYS A 1 420 ? 16.543 -3.910 32.669 1.00 27.42 ? 420 CYS A CB 1 ATOM 3310 S SG . CYS A 1 420 ? 15.949 -4.913 31.304 1.00 26.70 ? 420 CYS A SG 1 ATOM 3311 N N . ALA A 1 421 ? 15.089 -1.061 32.448 1.00 26.81 ? 421 ALA A N 1 ATOM 3312 C CA . ALA A 1 421 ? 14.038 -0.170 31.941 1.00 26.48 ? 421 ALA A CA 1 ATOM 3313 C C . ALA A 1 421 ? 14.601 1.006 31.137 1.00 25.97 ? 421 ALA A C 1 ATOM 3314 O O . ALA A 1 421 ? 14.035 1.375 30.139 1.00 26.52 ? 421 ALA A O 1 ATOM 3315 C CB . ALA A 1 421 ? 13.137 0.314 33.065 1.00 26.34 ? 421 ALA A CB 1 ATOM 3316 N N . VAL A 1 422 ? 15.727 1.574 31.553 1.00 25.99 ? 422 VAL A N 1 ATOM 3317 C CA . VAL A 1 422 ? 16.442 2.581 30.744 1.00 25.26 ? 422 VAL A CA 1 ATOM 3318 C C . VAL A 1 422 ? 16.775 2.006 29.358 1.00 24.29 ? 422 VAL A C 1 ATOM 3319 O O . VAL A 1 422 ? 16.436 2.585 28.331 1.00 24.62 ? 422 VAL A O 1 ATOM 3320 C CB . VAL A 1 422 ? 17.732 3.050 31.451 1.00 25.71 ? 422 VAL A CB 1 ATOM 3321 C CG1 . VAL A 1 422 ? 18.517 4.040 30.589 1.00 25.86 ? 422 VAL A CG1 1 ATOM 3322 C CG2 . VAL A 1 422 ? 17.410 3.629 32.847 1.00 25.78 ? 422 VAL A CG2 1 ATOM 3323 N N . TRP A 1 423 ? 17.382 0.830 29.340 1.00 23.27 ? 423 TRP A N 1 ATOM 3324 C CA . TRP A 1 423 ? 17.731 0.145 28.095 1.00 22.37 ? 423 TRP A CA 1 ATOM 3325 C C . TRP A 1 423 ? 16.496 -0.107 27.235 1.00 21.22 ? 423 TRP A C 1 ATOM 3326 O O . TRP A 1 423 ? 16.503 0.143 26.044 1.00 20.20 ? 423 TRP A O 1 ATOM 3327 C CB . TRP A 1 423 ? 18.401 -1.205 28.398 1.00 22.75 ? 423 TRP A CB 1 ATOM 3328 C CG . TRP A 1 423 ? 18.426 -2.162 27.205 1.00 23.75 ? 423 TRP A CG 1 ATOM 3329 C CD1 . TRP A 1 423 ? 19.310 -2.145 26.164 1.00 24.96 ? 423 TRP A CD1 1 ATOM 3330 C CD2 . TRP A 1 423 ? 17.556 -3.286 26.970 1.00 24.85 ? 423 TRP A CD2 1 ATOM 3331 N NE1 . TRP A 1 423 ? 19.020 -3.158 25.279 1.00 25.41 ? 423 TRP A NE1 1 ATOM 3332 C CE2 . TRP A 1 423 ? 17.960 -3.880 25.754 1.00 24.55 ? 423 TRP A CE2 1 ATOM 3333 C CE3 . TRP A 1 423 ? 16.462 -3.839 27.664 1.00 24.13 ? 423 TRP A CE3 1 ATOM 3334 C CZ2 . TRP A 1 423 ? 17.307 -4.994 25.206 1.00 23.77 ? 423 TRP A CZ2 1 ATOM 3335 C CZ3 . TRP A 1 423 ? 15.818 -4.941 27.123 1.00 24.23 ? 423 TRP A CZ3 1 ATOM 3336 C CH2 . TRP A 1 423 ? 16.241 -5.507 25.905 1.00 24.25 ? 423 TRP A CH2 1 ATOM 3337 N N . TRP A 1 424 ? 15.448 -0.634 27.863 1.00 20.67 ? 424 TRP A N 1 ATOM 3338 C CA . TRP A 1 424 ? 14.202 -0.988 27.188 1.00 20.45 ? 424 TRP A CA 1 ATOM 3339 C C . TRP A 1 424 ? 13.586 0.278 26.606 1.00 20.14 ? 424 TRP A C 1 ATOM 3340 O O . TRP A 1 424 ? 13.079 0.278 25.504 1.00 20.60 ? 424 TRP A O 1 ATOM 3341 C CB . TRP A 1 424 ? 13.283 -1.600 28.251 1.00 19.40 ? 424 TRP A CB 1 ATOM 3342 C CG . TRP A 1 424 ? 11.999 -2.303 27.853 1.00 19.29 ? 424 TRP A CG 1 ATOM 3343 C CD1 . TRP A 1 424 ? 10.752 -2.079 28.403 1.00 16.25 ? 424 TRP A CD1 1 ATOM 3344 C CD2 . TRP A 1 424 ? 11.839 -3.396 26.936 1.00 18.34 ? 424 TRP A CD2 1 ATOM 3345 N NE1 . TRP A 1 424 ? 9.833 -2.934 27.863 1.00 17.71 ? 424 TRP A NE1 1 ATOM 3346 C CE2 . TRP A 1 424 ? 10.461 -3.762 26.966 1.00 19.31 ? 424 TRP A CE2 1 ATOM 3347 C CE3 . TRP A 1 424 ? 12.712 -4.100 26.084 1.00 18.48 ? 424 TRP A CE3 1 ATOM 3348 C CZ2 . TRP A 1 424 ? 9.945 -4.773 26.172 1.00 17.30 ? 424 TRP A CZ2 1 ATOM 3349 C CZ3 . TRP A 1 424 ? 12.198 -5.117 25.312 1.00 17.79 ? 424 TRP A CZ3 1 ATOM 3350 C CH2 . TRP A 1 424 ? 10.829 -5.456 25.372 1.00 19.49 ? 424 TRP A CH2 1 ATOM 3351 N N . THR A 1 425 ? 13.624 1.362 27.366 1.00 21.44 ? 425 THR A N 1 ATOM 3352 C CA . THR A 1 425 ? 13.026 2.631 26.931 1.00 22.56 ? 425 THR A CA 1 ATOM 3353 C C . THR A 1 425 ? 13.681 3.127 25.635 1.00 23.38 ? 425 THR A C 1 ATOM 3354 O O . THR A 1 425 ? 13.001 3.450 24.663 1.00 24.41 ? 425 THR A O 1 ATOM 3355 C CB . THR A 1 425 ? 13.091 3.683 28.076 1.00 22.71 ? 425 THR A CB 1 ATOM 3356 O OG1 . THR A 1 425 ? 12.334 3.198 29.195 1.00 20.94 ? 425 THR A OG1 1 ATOM 3357 C CG2 . THR A 1 425 ? 12.582 5.053 27.629 1.00 21.85 ? 425 THR A CG2 1 ATOM 3358 N N . LYS A 1 426 ? 15.009 3.149 25.626 1.00 24.83 ? 426 LYS A N 1 ATOM 3359 C CA . LYS A 1 426 ? 15.790 3.568 24.466 1.00 25.06 ? 426 LYS A CA 1 ATOM 3360 C C . LYS A 1 426 ? 15.555 2.695 23.254 1.00 24.76 ? 426 LYS A C 1 ATOM 3361 O O . LYS A 1 426 ? 15.567 3.194 22.126 1.00 24.88 ? 426 LYS A O 1 ATOM 3362 C CB . LYS A 1 426 ? 17.279 3.606 24.815 1.00 25.89 ? 426 LYS A CB 1 ATOM 3363 C CG . LYS A 1 426 ? 18.195 4.100 23.692 1.00 29.83 ? 426 LYS A CG 1 ATOM 3364 C CD . LYS A 1 426 ? 17.881 5.543 23.319 1.00 34.35 ? 426 LYS A CD 1 ATOM 3365 C CE . LYS A 1 426 ? 19.100 6.230 22.706 1.00 36.44 ? 426 LYS A CE 1 ATOM 3366 N NZ . LYS A 1 426 ? 18.851 7.689 22.455 1.00 37.52 ? 426 LYS A NZ 1 ATOM 3367 N N . GLU A 1 427 ? 15.334 1.399 23.469 1.00 23.74 ? 427 GLU A N 1 ATOM 3368 C CA . GLU A 1 427 ? 15.048 0.514 22.351 1.00 23.92 ? 427 GLU A CA 1 ATOM 3369 C C . GLU A 1 427 ? 13.701 0.893 21.730 1.00 23.14 ? 427 GLU A C 1 ATOM 3370 O O . GLU A 1 427 ? 13.560 0.903 20.516 1.00 22.32 ? 427 GLU A O 1 ATOM 3371 C CB . GLU A 1 427 ? 15.040 -0.960 22.769 1.00 23.36 ? 427 GLU A CB 1 ATOM 3372 C CG . GLU A 1 427 ? 16.390 -1.543 23.166 1.00 25.56 ? 427 GLU A CG 1 ATOM 3373 C CD . GLU A 1 427 ? 17.498 -1.337 22.120 1.00 25.14 ? 427 GLU A CD 1 ATOM 3374 O OE1 . GLU A 1 427 ? 17.228 -1.384 20.901 1.00 26.96 ? 427 GLU A OE1 1 ATOM 3375 O OE2 . GLU A 1 427 ? 18.654 -1.112 22.532 1.00 27.10 ? 427 GLU A OE2 1 ATOM 3376 N N . PHE A 1 428 ? 12.722 1.209 22.571 1.00 23.57 ? 428 PHE A N 1 ATOM 3377 C CA . PHE A 1 428 ? 11.404 1.657 22.057 1.00 23.98 ? 428 PHE A CA 1 ATOM 3378 C C . PHE A 1 428 ? 11.451 3.015 21.393 1.00 24.27 ? 428 PHE A C 1 ATOM 3379 O O . PHE A 1 428 ? 10.798 3.210 20.400 1.00 25.61 ? 428 PHE A O 1 ATOM 3380 C CB . PHE A 1 428 ? 10.358 1.656 23.159 1.00 23.19 ? 428 PHE A CB 1 ATOM 3381 C CG . PHE A 1 428 ? 9.758 0.322 23.388 1.00 23.06 ? 428 PHE A CG 1 ATOM 3382 C CD1 . PHE A 1 428 ? 8.850 -0.204 22.482 1.00 24.58 ? 428 PHE A CD1 1 ATOM 3383 C CD2 . PHE A 1 428 ? 10.111 -0.425 24.496 1.00 23.56 ? 428 PHE A CD2 1 ATOM 3384 C CE1 . PHE A 1 428 ? 8.306 -1.446 22.691 1.00 24.99 ? 428 PHE A CE1 1 ATOM 3385 C CE2 . PHE A 1 428 ? 9.566 -1.665 24.706 1.00 24.18 ? 428 PHE A CE2 1 ATOM 3386 C CZ . PHE A 1 428 ? 8.661 -2.174 23.814 1.00 24.31 ? 428 PHE A CZ 1 ATOM 3387 N N . GLU A 1 429 ? 12.209 3.943 21.982 1.00 26.02 ? 429 GLU A N 1 ATOM 3388 C CA . GLU A 1 429 ? 12.519 5.261 21.425 1.00 27.12 ? 429 GLU A CA 1 ATOM 3389 C C . GLU A 1 429 ? 13.056 5.113 20.017 1.00 26.72 ? 429 GLU A C 1 ATOM 3390 O O . GLU A 1 429 ? 12.482 5.637 19.076 1.00 26.70 ? 429 GLU A O 1 ATOM 3391 C CB . GLU A 1 429 ? 13.574 5.939 22.324 1.00 28.08 ? 429 GLU A CB 1 ATOM 3392 C CG . GLU A 1 429 ? 13.751 7.445 22.165 1.00 32.39 ? 429 GLU A CG 1 ATOM 3393 C CD . GLU A 1 429 ? 14.132 8.135 23.484 1.00 37.25 ? 429 GLU A CD 1 ATOM 3394 O OE1 . GLU A 1 429 ? 14.539 7.444 24.457 1.00 39.95 ? 429 GLU A OE1 1 ATOM 3395 O OE2 . GLU A 1 429 ? 14.012 9.379 23.552 1.00 40.24 ? 429 GLU A OE2 1 ATOM 3396 N N . LEU A 1 430 ? 14.166 4.390 19.873 1.00 26.45 ? 430 LEU A N 1 ATOM 3397 C CA . LEU A 1 430 ? 14.745 4.137 18.556 1.00 26.09 ? 430 LEU A CA 1 ATOM 3398 C C . LEU A 1 430 ? 13.786 3.479 17.568 1.00 25.43 ? 430 LEU A C 1 ATOM 3399 O O . LEU A 1 430 ? 13.703 3.896 16.415 1.00 25.34 ? 430 LEU A O 1 ATOM 3400 C CB . LEU A 1 430 ? 16.022 3.312 18.681 1.00 26.84 ? 430 LEU A CB 1 ATOM 3401 C CG . LEU A 1 430 ? 17.143 3.985 19.475 1.00 26.92 ? 430 LEU A CG 1 ATOM 3402 C CD1 . LEU A 1 430 ? 18.144 2.946 19.915 1.00 30.09 ? 430 LEU A CD1 1 ATOM 3403 C CD2 . LEU A 1 430 ? 17.805 5.104 18.649 1.00 31.12 ? 430 LEU A CD2 1 ATOM 3404 N N . PHE A 1 431 ? 13.056 2.457 18.004 1.00 25.18 ? 431 PHE A N 1 ATOM 3405 C CA . PHE A 1 431 ? 12.097 1.816 17.099 1.00 24.65 ? 431 PHE A CA 1 ATOM 3406 C C . PHE A 1 431 ? 10.911 2.730 16.737 1.00 24.41 ? 431 PHE A C 1 ATOM 3407 O O . PHE A 1 431 ? 10.425 2.709 15.599 1.00 23.22 ? 431 PHE A O 1 ATOM 3408 C CB . PHE A 1 431 ? 11.618 0.460 17.638 1.00 24.81 ? 431 PHE A CB 1 ATOM 3409 C CG . PHE A 1 431 ? 11.010 -0.420 16.576 1.00 26.20 ? 431 PHE A CG 1 ATOM 3410 C CD1 . PHE A 1 431 ? 11.724 -0.712 15.412 1.00 24.99 ? 431 PHE A CD1 1 ATOM 3411 C CD2 . PHE A 1 431 ? 9.719 -0.937 16.726 1.00 26.69 ? 431 PHE A CD2 1 ATOM 3412 C CE1 . PHE A 1 431 ? 11.174 -1.506 14.436 1.00 26.34 ? 431 PHE A CE1 1 ATOM 3413 C CE2 . PHE A 1 431 ? 9.156 -1.740 15.751 1.00 25.02 ? 431 PHE A CE2 1 ATOM 3414 C CZ . PHE A 1 431 ? 9.879 -2.025 14.600 1.00 26.81 ? 431 PHE A CZ 1 ATOM 3415 N N . HIS A 1 432 ? 10.457 3.532 17.699 1.00 25.13 ? 432 HIS A N 1 ATOM 3416 C CA . HIS A 1 432 ? 9.314 4.432 17.467 1.00 26.73 ? 432 HIS A CA 1 ATOM 3417 C C . HIS A 1 432 ? 9.622 5.483 16.398 1.00 27.33 ? 432 HIS A C 1 ATOM 3418 O O . HIS A 1 432 ? 8.729 5.937 15.683 1.00 26.74 ? 432 HIS A O 1 ATOM 3419 C CB . HIS A 1 432 ? 8.872 5.120 18.766 1.00 26.34 ? 432 HIS A CB 1 ATOM 3420 C CG . HIS A 1 432 ? 7.525 5.770 18.671 1.00 27.68 ? 432 HIS A CG 1 ATOM 3421 N ND1 . HIS A 1 432 ? 7.359 7.130 18.497 1.00 28.48 ? 432 HIS A ND1 1 ATOM 3422 C CD2 . HIS A 1 432 ? 6.276 5.242 18.704 1.00 26.63 ? 432 HIS A CD2 1 ATOM 3423 C CE1 . HIS A 1 432 ? 6.070 7.408 18.429 1.00 25.99 ? 432 HIS A CE1 1 ATOM 3424 N NE2 . HIS A 1 432 ? 5.393 6.283 18.563 1.00 26.13 ? 432 HIS A NE2 1 ATOM 3425 N N . ASN A 1 433 ? 10.899 5.852 16.297 1.00 28.20 ? 433 ASN A N 1 ATOM 3426 C CA . ASN A 1 433 ? 11.365 6.779 15.258 1.00 29.45 ? 433 ASN A CA 1 ATOM 3427 C C . ASN A 1 433 ? 11.192 6.228 13.854 1.00 29.31 ? 433 ASN A C 1 ATOM 3428 O O . ASN A 1 433 ? 11.140 6.987 12.895 1.00 30.48 ? 433 ASN A O 1 ATOM 3429 C CB . ASN A 1 433 ? 12.829 7.172 15.514 1.00 29.42 ? 433 ASN A CB 1 ATOM 3430 C CG . ASN A 1 433 ? 12.981 8.037 16.736 1.00 31.96 ? 433 ASN A CG 1 ATOM 3431 O OD1 . ASN A 1 433 ? 12.003 8.620 17.227 1.00 35.01 ? 433 ASN A OD1 1 ATOM 3432 N ND2 . ASN A 1 433 ? 14.203 8.131 17.249 1.00 33.80 ? 433 ASN A ND2 1 ATOM 3433 N N . GLN A 1 434 ? 11.095 4.903 13.743 1.00 29.16 ? 434 GLN A N 1 ATOM 3434 C CA . GLN A 1 434 ? 10.915 4.212 12.470 1.00 29.08 ? 434 GLN A CA 1 ATOM 3435 C C . GLN A 1 434 ? 9.436 3.872 12.183 1.00 28.37 ? 434 GLN A C 1 ATOM 3436 O O . GLN A 1 434 ? 8.918 4.165 11.105 1.00 27.99 ? 434 GLN A O 1 ATOM 3437 C CB . GLN A 1 434 ? 11.755 2.936 12.453 1.00 29.01 ? 434 GLN A CB 1 ATOM 3438 C CG . GLN A 1 434 ? 13.243 3.155 12.833 1.00 31.38 ? 434 GLN A CG 1 ATOM 3439 C CD . GLN A 1 434 ? 14.011 1.843 12.936 1.00 31.84 ? 434 GLN A CD 1 ATOM 3440 O OE1 . GLN A 1 434 ? 14.505 1.469 14.013 1.00 35.96 ? 434 GLN A OE1 1 ATOM 3441 N NE2 . GLN A 1 434 ? 14.097 1.123 11.816 1.00 36.04 ? 434 GLN A NE2 1 ATOM 3442 N N . VAL A 1 435 ? 8.784 3.226 13.148 1.00 27.73 ? 435 VAL A N 1 ATOM 3443 C CA . VAL A 1 435 ? 7.378 2.803 13.049 1.00 27.09 ? 435 VAL A CA 1 ATOM 3444 C C . VAL A 1 435 ? 6.678 3.478 14.225 1.00 26.73 ? 435 VAL A C 1 ATOM 3445 O O . VAL A 1 435 ? 6.977 3.170 15.370 1.00 26.27 ? 435 VAL A O 1 ATOM 3446 C CB . VAL A 1 435 ? 7.252 1.260 13.180 1.00 27.24 ? 435 VAL A CB 1 ATOM 3447 C CG1 . VAL A 1 435 ? 5.820 0.778 12.929 1.00 25.76 ? 435 VAL A CG1 1 ATOM 3448 C CG2 . VAL A 1 435 ? 8.234 0.547 12.259 1.00 27.75 ? 435 VAL A CG2 1 ATOM 3449 N N . GLU A 1 436 ? 5.785 4.427 13.954 1.00 27.02 ? 436 GLU A N 1 ATOM 3450 C CA . GLU A 1 436 ? 5.078 5.171 15.014 1.00 27.44 ? 436 GLU A CA 1 ATOM 3451 C C . GLU A 1 436 ? 3.847 4.419 15.564 1.00 25.79 ? 436 GLU A C 1 ATOM 3452 O O . GLU A 1 436 ? 2.687 4.856 15.389 1.00 25.61 ? 436 GLU A O 1 ATOM 3453 C CB . GLU A 1 436 ? 4.638 6.547 14.513 1.00 27.72 ? 436 GLU A CB 1 ATOM 3454 C CG . GLU A 1 436 ? 5.732 7.576 14.269 1.00 30.93 ? 436 GLU A CG 1 ATOM 3455 C CD . GLU A 1 436 ? 5.186 8.894 13.680 1.00 32.06 ? 436 GLU A CD 1 ATOM 3456 O OE1 . GLU A 1 436 ? 4.073 8.903 13.079 1.00 37.46 ? 436 GLU A OE1 1 ATOM 3457 O OE2 . GLU A 1 436 ? 5.874 9.933 13.821 1.00 37.80 ? 436 GLU A OE2 1 ATOM 3458 N N . PHE A 1 437 ? 4.117 3.306 16.242 1.00 24.09 ? 437 PHE A N 1 ATOM 3459 C CA . PHE A 1 437 ? 3.101 2.466 16.896 1.00 22.60 ? 437 PHE A CA 1 ATOM 3460 C C . PHE A 1 437 ? 2.504 3.197 18.093 1.00 22.22 ? 437 PHE A C 1 ATOM 3461 O O . PHE A 1 437 ? 3.084 4.142 18.621 1.00 22.11 ? 437 PHE A O 1 ATOM 3462 C CB . PHE A 1 437 ? 3.702 1.123 17.349 1.00 21.42 ? 437 PHE A CB 1 ATOM 3463 C CG . PHE A 1 437 ? 4.835 1.282 18.315 1.00 19.80 ? 437 PHE A CG 1 ATOM 3464 C CD1 . PHE A 1 437 ? 4.599 1.363 19.674 1.00 16.76 ? 437 PHE A CD1 1 ATOM 3465 C CD2 . PHE A 1 437 ? 6.140 1.409 17.854 1.00 19.65 ? 437 PHE A CD2 1 ATOM 3466 C CE1 . PHE A 1 437 ? 5.631 1.552 20.573 1.00 17.98 ? 437 PHE A CE1 1 ATOM 3467 C CE2 . PHE A 1 437 ? 7.191 1.585 18.747 1.00 16.01 ? 437 PHE A CE2 1 ATOM 3468 C CZ . PHE A 1 437 ? 6.948 1.681 20.096 1.00 18.20 ? 437 PHE A CZ 1 ATOM 3469 N N . ASP A 1 438 ? 1.331 2.740 18.522 1.00 21.94 ? 438 ASP A N 1 ATOM 3470 C CA . ASP A 1 438 ? 0.552 3.459 19.532 1.00 20.53 ? 438 ASP A CA 1 ATOM 3471 C C . ASP A 1 438 ? 0.530 2.718 20.846 1.00 19.55 ? 438 ASP A C 1 ATOM 3472 O O . ASP A 1 438 ? 0.346 3.315 21.893 1.00 19.97 ? 438 ASP A O 1 ATOM 3473 C CB . ASP A 1 438 ? -0.858 3.659 18.994 1.00 20.30 ? 438 ASP A CB 1 ATOM 3474 C CG . ASP A 1 438 ? -0.865 4.554 17.789 1.00 19.57 ? 438 ASP A CG 1 ATOM 3475 O OD1 . ASP A 1 438 ? -0.641 5.763 17.984 1.00 20.47 ? 438 ASP A OD1 1 ATOM 3476 O OD2 . ASP A 1 438 ? -1.038 4.056 16.661 1.00 19.56 ? 438 ASP A OD2 1 ATOM 3477 N N . GLY A 1 439 ? 0.711 1.407 20.772 1.00 18.82 ? 439 GLY A N 1 ATOM 3478 C CA . GLY A 1 439 ? 0.727 0.577 21.951 1.00 17.89 ? 439 GLY A CA 1 ATOM 3479 C C . GLY A 1 439 ? 1.588 -0.651 21.774 1.00 17.32 ? 439 GLY A C 1 ATOM 3480 O O . GLY A 1 439 ? 2.098 -0.920 20.683 1.00 16.87 ? 439 GLY A O 1 ATOM 3481 N N . ILE A 1 440 ? 1.727 -1.394 22.864 1.00 16.64 ? 440 ILE A N 1 ATOM 3482 C CA . ILE A 1 440 ? 2.647 -2.500 22.941 1.00 16.53 ? 440 ILE A CA 1 ATOM 3483 C C . ILE A 1 440 ? 1.961 -3.732 23.497 1.00 16.15 ? 440 ILE A C 1 ATOM 3484 O O . ILE A 1 440 ? 1.301 -3.681 24.512 1.00 16.19 ? 440 ILE A O 1 ATOM 3485 C CB . ILE A 1 440 ? 3.898 -2.135 23.811 1.00 16.17 ? 440 ILE A CB 1 ATOM 3486 C CG1 . ILE A 1 440 ? 4.662 -0.959 23.175 1.00 17.42 ? 440 ILE A CG1 1 ATOM 3487 C CG2 . ILE A 1 440 ? 4.872 -3.268 23.842 1.00 16.51 ? 440 ILE A CG2 1 ATOM 3488 C CD1 . ILE A 1 440 ? 5.271 0.009 24.170 1.00 17.98 ? 440 ILE A CD1 1 ATOM 3489 N N . TRP A 1 441 ? 2.178 -4.849 22.820 1.00 15.96 ? 441 TRP A N 1 ATOM 3490 C CA . TRP A 1 441 ? 1.677 -6.139 23.232 1.00 15.83 ? 441 TRP A CA 1 ATOM 3491 C C . TRP A 1 441 ? 2.919 -6.962 23.653 1.00 16.35 ? 441 TRP A C 1 ATOM 3492 O O . TRP A 1 441 ? 3.739 -7.342 22.825 1.00 14.66 ? 441 TRP A O 1 ATOM 3493 C CB . TRP A 1 441 ? 0.810 -6.712 22.084 1.00 15.51 ? 441 TRP A CB 1 ATOM 3494 C CG . TRP A 1 441 ? 0.492 -8.168 22.086 1.00 14.34 ? 441 TRP A CG 1 ATOM 3495 C CD1 . TRP A 1 441 ? 0.462 -8.997 23.148 1.00 15.65 ? 441 TRP A CD1 1 ATOM 3496 C CD2 . TRP A 1 441 ? 0.101 -8.951 20.952 1.00 15.68 ? 441 TRP A CD2 1 ATOM 3497 N NE1 . TRP A 1 441 ? 0.127 -10.260 22.749 1.00 15.94 ? 441 TRP A NE1 1 ATOM 3498 C CE2 . TRP A 1 441 ? -0.115 -10.252 21.402 1.00 14.49 ? 441 TRP A CE2 1 ATOM 3499 C CE3 . TRP A 1 441 ? -0.082 -8.666 19.590 1.00 17.32 ? 441 TRP A CE3 1 ATOM 3500 C CZ2 . TRP A 1 441 ? -0.489 -11.287 20.547 1.00 16.69 ? 441 TRP A CZ2 1 ATOM 3501 C CZ3 . TRP A 1 441 ? -0.437 -9.668 18.747 1.00 15.09 ? 441 TRP A CZ3 1 ATOM 3502 C CH2 . TRP A 1 441 ? -0.647 -10.974 19.219 1.00 16.82 ? 441 TRP A CH2 1 ATOM 3503 N N . ILE A 1 442 ? 3.068 -7.146 24.975 1.00 16.30 ? 442 ILE A N 1 ATOM 3504 C CA . ILE A 1 442 ? 4.169 -7.903 25.551 1.00 17.49 ? 442 ILE A CA 1 ATOM 3505 C C . ILE A 1 442 ? 3.783 -9.371 25.760 1.00 17.61 ? 442 ILE A C 1 ATOM 3506 O O . ILE A 1 442 ? 2.801 -9.698 26.437 1.00 18.04 ? 442 ILE A O 1 ATOM 3507 C CB . ILE A 1 442 ? 4.810 -7.178 26.786 1.00 18.34 ? 442 ILE A CB 1 ATOM 3508 C CG1 . ILE A 1 442 ? 3.760 -6.827 27.869 1.00 18.33 ? 442 ILE A CG1 1 ATOM 3509 C CG2 . ILE A 1 442 ? 5.523 -5.898 26.302 1.00 16.58 ? 442 ILE A CG2 1 ATOM 3510 C CD1 . ILE A 1 442 ? 4.335 -6.505 29.262 1.00 17.07 ? 442 ILE A CD1 1 ATOM 3511 N N . ASP A 1 443 ? 4.535 -10.245 25.087 1.00 17.29 ? 443 ASP A N 1 ATOM 3512 C CA . ASP A 1 443 ? 4.203 -11.642 24.944 1.00 17.61 ? 443 ASP A CA 1 ATOM 3513 C C . ASP A 1 443 ? 5.325 -12.519 25.508 1.00 18.07 ? 443 ASP A C 1 ATOM 3514 O O . ASP A 1 443 ? 6.458 -12.054 25.694 1.00 17.54 ? 443 ASP A O 1 ATOM 3515 C CB . ASP A 1 443 ? 3.986 -11.953 23.459 1.00 16.77 ? 443 ASP A CB 1 ATOM 3516 C CG . ASP A 1 443 ? 3.349 -13.327 23.208 1.00 17.66 ? 443 ASP A CG 1 ATOM 3517 O OD1 . ASP A 1 443 ? 2.670 -13.848 24.112 1.00 20.97 ? 443 ASP A OD1 1 ATOM 3518 O OD2 . ASP A 1 443 ? 3.554 -13.896 22.105 1.00 14.13 ? 443 ASP A OD2 1 ATOM 3519 N N . MET A 1 444 ? 4.992 -13.784 25.775 1.00 18.61 ? 444 MET A N 1 ATOM 3520 C CA . MET A 1 444 ? 5.985 -14.810 26.087 1.00 19.00 ? 444 MET A CA 1 ATOM 3521 C C . MET A 1 444 ? 6.794 -14.445 27.306 1.00 18.37 ? 444 MET A C 1 ATOM 3522 O O . MET A 1 444 ? 7.952 -14.841 27.417 1.00 18.21 ? 444 MET A O 1 ATOM 3523 C CB . MET A 1 444 ? 6.939 -14.983 24.890 1.00 19.81 ? 444 MET A CB 1 ATOM 3524 C CG . MET A 1 444 ? 6.235 -15.305 23.584 1.00 18.52 ? 444 MET A CG 1 ATOM 3525 S SD . MET A 1 444 ? 5.840 -17.014 23.539 1.00 22.28 ? 444 MET A SD 1 ATOM 3526 C CE . MET A 1 444 ? 7.495 -17.766 23.353 1.00 19.00 ? 444 MET A CE 1 ATOM 3527 N N . ASN A 1 445 ? 6.171 -13.703 28.228 1.00 17.90 ? 445 ASN A N 1 ATOM 3528 C CA . ASN A 1 445 ? 6.877 -13.072 29.345 1.00 17.22 ? 445 ASN A CA 1 ATOM 3529 C C . ASN A 1 445 ? 6.722 -13.737 30.711 1.00 18.25 ? 445 ASN A C 1 ATOM 3530 O O . ASN A 1 445 ? 6.821 -13.071 31.746 1.00 17.49 ? 445 ASN A O 1 ATOM 3531 C CB . ASN A 1 445 ? 6.534 -11.579 29.428 1.00 16.09 ? 445 ASN A CB 1 ATOM 3532 C CG . ASN A 1 445 ? 5.011 -11.324 29.518 1.00 17.21 ? 445 ASN A CG 1 ATOM 3533 O OD1 . ASN A 1 445 ? 4.212 -12.235 29.372 1.00 12.83 ? 445 ASN A OD1 1 ATOM 3534 N ND2 . ASN A 1 445 ? 4.637 -10.103 29.747 1.00 18.05 ? 445 ASN A ND2 1 ATOM 3535 N N . GLU A 1 446 ? 6.538 -15.058 30.694 1.00 19.09 ? 446 GLU A N 1 ATOM 3536 C CA . GLU A 1 446 ? 6.493 -15.892 31.914 1.00 20.24 ? 446 GLU A CA 1 ATOM 3537 C C . GLU A 1 446 ? 7.746 -16.027 32.766 1.00 21.38 ? 446 GLU A C 1 ATOM 3538 O O . GLU A 1 446 ? 7.588 -16.168 33.974 1.00 22.74 ? 446 GLU A O 1 ATOM 3539 C CB . GLU A 1 446 ? 6.010 -17.305 31.600 1.00 20.32 ? 446 GLU A CB 1 ATOM 3540 C CG . GLU A 1 446 ? 4.553 -17.404 31.220 1.00 20.73 ? 446 GLU A CG 1 ATOM 3541 C CD . GLU A 1 446 ? 4.241 -16.820 29.840 1.00 24.51 ? 446 GLU A CD 1 ATOM 3542 O OE1 . GLU A 1 446 ? 5.115 -16.896 28.942 1.00 23.95 ? 446 GLU A OE1 1 ATOM 3543 O OE2 . GLU A 1 446 ? 3.101 -16.309 29.651 1.00 22.00 ? 446 GLU A OE2 1 ATOM 3544 N N . VAL A 1 447 ? 8.982 -16.029 32.232 1.00 21.27 ? 447 VAL A N 1 ATOM 3545 C CA . VAL A 1 447 ? 9.354 -15.876 30.838 1.00 20.47 ? 447 VAL A CA 1 ATOM 3546 C C . VAL A 1 447 ? 9.416 -17.238 30.158 1.00 21.02 ? 447 VAL A C 1 ATOM 3547 O O . VAL A 1 447 ? 9.669 -18.257 30.788 1.00 21.04 ? 447 VAL A O 1 ATOM 3548 C CB . VAL A 1 447 ? 10.701 -15.108 30.692 1.00 20.75 ? 447 VAL A CB 1 ATOM 3549 C CG1 . VAL A 1 447 ? 11.869 -15.972 31.137 1.00 19.78 ? 447 VAL A CG1 1 ATOM 3550 C CG2 . VAL A 1 447 ? 10.911 -14.621 29.262 1.00 19.19 ? 447 VAL A CG2 1 ATOM 3551 N N . SER A 1 448 ? 9.096 -17.259 28.871 1.00 21.58 ? 448 SER A N 1 ATOM 3552 C CA . SER A 1 448 ? 8.937 -18.502 28.131 1.00 21.01 ? 448 SER A CA 1 ATOM 3553 C C . SER A 1 448 ? 10.227 -18.821 27.377 1.00 20.29 ? 448 SER A C 1 ATOM 3554 O O . SER A 1 448 ? 10.897 -17.916 26.882 1.00 20.36 ? 448 SER A O 1 ATOM 3555 C CB . SER A 1 448 ? 7.763 -18.374 27.169 1.00 20.92 ? 448 SER A CB 1 ATOM 3556 O OG . SER A 1 448 ? 7.557 -19.560 26.428 1.00 23.49 ? 448 SER A OG 1 ATOM 3557 N N . ASN A 1 449 ? 10.569 -20.105 27.314 1.00 18.91 ? 449 ASN A N 1 ATOM 3558 C CA . ASN A 1 449 ? 11.841 -20.557 26.702 1.00 18.71 ? 449 ASN A CA 1 ATOM 3559 C C . ASN A 1 449 ? 11.560 -21.822 25.872 1.00 18.66 ? 449 ASN A C 1 ATOM 3560 O O . ASN A 1 449 ? 10.926 -22.753 26.352 1.00 18.68 ? 449 ASN A O 1 ATOM 3561 C CB . ASN A 1 449 ? 12.858 -20.818 27.827 1.00 17.79 ? 449 ASN A CB 1 ATOM 3562 C CG . ASN A 1 449 ? 14.328 -20.920 27.344 1.00 17.97 ? 449 ASN A CG 1 ATOM 3563 O OD1 . ASN A 1 449 ? 14.628 -20.755 26.176 1.00 19.67 ? 449 ASN A OD1 1 ATOM 3564 N ND2 . ASN A 1 449 ? 15.235 -21.217 28.278 1.00 14.91 ? 449 ASN A ND2 1 ATOM 3565 N N . PHE A 1 450 ? 11.974 -21.854 24.613 1.00 18.85 ? 450 PHE A N 1 ATOM 3566 C CA . PHE A 1 450 ? 11.755 -23.053 23.804 1.00 19.80 ? 450 PHE A CA 1 ATOM 3567 C C . PHE A 1 450 ? 12.649 -24.241 24.213 1.00 20.94 ? 450 PHE A C 1 ATOM 3568 O O . PHE A 1 450 ? 12.443 -25.373 23.758 1.00 22.27 ? 450 PHE A O 1 ATOM 3569 C CB . PHE A 1 450 ? 11.936 -22.746 22.318 1.00 19.92 ? 450 PHE A CB 1 ATOM 3570 C CG . PHE A 1 450 ? 10.892 -21.829 21.752 1.00 19.13 ? 450 PHE A CG 1 ATOM 3571 C CD1 . PHE A 1 450 ? 9.652 -21.646 22.408 1.00 20.01 ? 450 PHE A CD1 1 ATOM 3572 C CD2 . PHE A 1 450 ? 11.102 -21.204 20.539 1.00 17.42 ? 450 PHE A CD2 1 ATOM 3573 C CE1 . PHE A 1 450 ? 8.677 -20.811 21.877 1.00 16.56 ? 450 PHE A CE1 1 ATOM 3574 C CE2 . PHE A 1 450 ? 10.124 -20.366 20.001 1.00 20.65 ? 450 PHE A CE2 1 ATOM 3575 C CZ . PHE A 1 450 ? 8.900 -20.181 20.678 1.00 18.07 ? 450 PHE A CZ 1 ATOM 3576 N N . VAL A 1 451 ? 13.629 -23.982 25.072 1.00 20.53 ? 451 VAL A N 1 ATOM 3577 C CA . VAL A 1 451 ? 14.400 -25.045 25.699 1.00 21.33 ? 451 VAL A CA 1 ATOM 3578 C C . VAL A 1 451 ? 14.094 -25.023 27.197 1.00 21.72 ? 451 VAL A C 1 ATOM 3579 O O . VAL A 1 451 ? 13.641 -24.016 27.723 1.00 21.63 ? 451 VAL A O 1 ATOM 3580 C CB . VAL A 1 451 ? 15.947 -24.904 25.444 1.00 20.08 ? 451 VAL A CB 1 ATOM 3581 C CG1 . VAL A 1 451 ? 16.246 -25.101 23.988 1.00 22.62 ? 451 VAL A CG1 1 ATOM 3582 C CG2 . VAL A 1 451 ? 16.457 -23.568 25.883 1.00 19.19 ? 451 VAL A CG2 1 ATOM 3583 N N . ASP A 1 452 ? 14.325 -26.141 27.870 1.00 22.28 ? 452 ASP A N 1 ATOM 3584 C CA . ASP A 1 452 ? 14.057 -26.244 29.291 1.00 23.43 ? 452 ASP A CA 1 ATOM 3585 C C . ASP A 1 452 ? 15.259 -25.726 30.087 1.00 23.52 ? 452 ASP A C 1 ATOM 3586 O O . ASP A 1 452 ? 16.312 -26.365 30.115 1.00 25.15 ? 452 ASP A O 1 ATOM 3587 C CB . ASP A 1 452 ? 13.717 -27.701 29.660 1.00 23.19 ? 452 ASP A CB 1 ATOM 3588 C CG . ASP A 1 452 ? 12.349 -28.157 29.124 1.00 25.86 ? 452 ASP A CG 1 ATOM 3589 O OD1 . ASP A 1 452 ? 11.485 -27.307 28.756 1.00 26.74 ? 452 ASP A OD1 1 ATOM 3590 O OD2 . ASP A 1 452 ? 12.130 -29.383 29.075 1.00 28.29 ? 452 ASP A OD2 1 ATOM 3591 N N . GLY A 1 453 ? 15.113 -24.556 30.708 1.00 23.59 ? 453 GLY A N 1 ATOM 3592 C CA . GLY A 1 453 ? 16.157 -24.001 31.555 1.00 23.50 ? 453 GLY A CA 1 ATOM 3593 C C . GLY A 1 453 ? 17.071 -23.089 30.771 1.00 24.36 ? 453 GLY A C 1 ATOM 3594 O O . GLY A 1 453 ? 17.009 -21.865 30.891 1.00 24.43 ? 453 GLY A O 1 ATOM 3595 N N . SER A 1 454 ? 17.947 -23.700 29.985 1.00 24.43 ? 454 SER A N 1 ATOM 3596 C CA . SER A 1 454 ? 18.899 -22.976 29.160 1.00 24.54 ? 454 SER A CA 1 ATOM 3597 C C . SER A 1 454 ? 19.335 -23.925 28.051 1.00 24.55 ? 454 SER A C 1 ATOM 3598 O O . SER A 1 454 ? 18.947 -25.105 28.044 1.00 25.00 ? 454 SER A O 1 ATOM 3599 C CB . SER A 1 454 ? 20.125 -22.557 29.987 1.00 24.60 ? 454 SER A CB 1 ATOM 3600 O OG . SER A 1 454 ? 20.903 -23.692 30.334 1.00 23.89 ? 454 SER A OG 1 ATOM 3601 N N . VAL A 1 455 ? 20.142 -23.425 27.118 1.00 24.86 ? 455 VAL A N 1 ATOM 3602 C CA . VAL A 1 455 ? 20.678 -24.285 26.049 1.00 24.27 ? 455 VAL A CA 1 ATOM 3603 C C . VAL A 1 455 ? 21.529 -25.454 26.572 1.00 25.07 ? 455 VAL A C 1 ATOM 3604 O O . VAL A 1 455 ? 21.690 -26.467 25.892 1.00 25.55 ? 455 VAL A O 1 ATOM 3605 C CB . VAL A 1 455 ? 21.384 -23.502 24.911 1.00 24.31 ? 455 VAL A CB 1 ATOM 3606 C CG1 . VAL A 1 455 ? 20.400 -22.597 24.219 1.00 21.21 ? 455 VAL A CG1 1 ATOM 3607 C CG2 . VAL A 1 455 ? 22.627 -22.747 25.392 1.00 22.30 ? 455 VAL A CG2 1 ATOM 3608 N N . SER A 1 456 ? 22.019 -25.341 27.794 1.00 25.78 ? 456 SER A N 1 ATOM 3609 C CA . SER A 1 456 ? 22.684 -26.481 28.424 1.00 27.44 ? 456 SER A CA 1 ATOM 3610 C C . SER A 1 456 ? 21.945 -27.052 29.645 1.00 26.90 ? 456 SER A C 1 ATOM 3611 O O . SER A 1 456 ? 22.563 -27.610 30.539 1.00 28.25 ? 456 SER A O 1 ATOM 3612 C CB . SER A 1 456 ? 24.137 -26.131 28.733 1.00 27.04 ? 456 SER A CB 1 ATOM 3613 O OG . SER A 1 456 ? 24.180 -25.101 29.688 1.00 31.51 ? 456 SER A OG 1 ATOM 3614 N N . GLY A 1 457 ? 20.615 -26.923 29.662 1.00 26.90 ? 457 GLY A N 1 ATOM 3615 C CA . GLY A 1 457 ? 19.794 -27.417 30.768 1.00 26.47 ? 457 GLY A CA 1 ATOM 3616 C C . GLY A 1 457 ? 20.072 -26.693 32.076 1.00 26.54 ? 457 GLY A C 1 ATOM 3617 O O . GLY A 1 457 ? 20.531 -25.554 32.076 1.00 27.31 ? 457 GLY A O 1 ATOM 3618 N N . CYS A 1 458 ? 19.806 -27.368 33.188 1.00 26.46 ? 458 CYS A N 1 ATOM 3619 C CA . CYS A 1 458 ? 20.003 -26.822 34.522 1.00 26.94 ? 458 CYS A CA 1 ATOM 3620 C C . CYS A 1 458 ? 20.707 -27.844 35.379 1.00 26.60 ? 458 CYS A C 1 ATOM 3621 O O . CYS A 1 458 ? 20.460 -29.036 35.255 1.00 26.49 ? 458 CYS A O 1 ATOM 3622 C CB . CYS A 1 458 ? 18.657 -26.591 35.211 1.00 27.18 ? 458 CYS A CB 1 ATOM 3623 S SG . CYS A 1 458 ? 17.381 -25.951 34.208 1.00 31.68 ? 458 CYS A SG 1 ATOM 3624 N N . SER A 1 459 ? 21.521 -27.368 36.299 1.00 26.90 ? 459 SER A N 1 ATOM 3625 C CA . SER A 1 459 ? 22.125 -28.263 37.279 1.00 27.75 ? 459 SER A CA 1 ATOM 3626 C C . SER A 1 459 ? 21.059 -28.864 38.182 1.00 27.00 ? 459 SER A C 1 ATOM 3627 O O . SER A 1 459 ? 20.050 -28.224 38.507 1.00 26.70 ? 459 SER A O 1 ATOM 3628 C CB . SER A 1 459 ? 23.156 -27.518 38.123 1.00 27.66 ? 459 SER A CB 1 ATOM 3629 O OG . SER A 1 459 ? 23.956 -26.710 37.282 1.00 29.99 ? 459 SER A OG 1 ATOM 3630 N N . THR A 1 460 ? 21.297 -30.112 38.557 1.00 26.48 ? 460 THR A N 1 ATOM 3631 C CA . THR A 1 460 ? 20.562 -30.782 39.609 1.00 26.17 ? 460 THR A CA 1 ATOM 3632 C C . THR A 1 460 ? 20.973 -30.145 40.930 1.00 25.91 ? 460 THR A C 1 ATOM 3633 O O . THR A 1 460 ? 22.150 -30.181 41.334 1.00 25.66 ? 460 THR A O 1 ATOM 3634 C CB . THR A 1 460 ? 20.856 -32.291 39.576 1.00 25.98 ? 460 THR A CB 1 ATOM 3635 O OG1 . THR A 1 460 ? 20.540 -32.791 38.268 1.00 25.07 ? 460 THR A OG1 1 ATOM 3636 C CG2 . THR A 1 460 ? 20.044 -33.037 40.622 1.00 27.77 ? 460 THR A CG2 1 ATOM 3637 N N . ASN A 1 461 ? 19.995 -29.505 41.570 1.00 24.30 ? 461 ASN A N 1 ATOM 3638 C CA . ASN A 1 461 ? 20.157 -28.861 42.865 1.00 23.24 ? 461 ASN A CA 1 ATOM 3639 C C . ASN A 1 461 ? 18.755 -28.616 43.442 1.00 23.25 ? 461 ASN A C 1 ATOM 3640 O O . ASN A 1 461 ? 17.770 -28.914 42.770 1.00 21.78 ? 461 ASN A O 1 ATOM 3641 C CB . ASN A 1 461 ? 20.993 -27.567 42.777 1.00 23.31 ? 461 ASN A CB 1 ATOM 3642 C CG . ASN A 1 461 ? 20.380 -26.522 41.889 1.00 24.39 ? 461 ASN A CG 1 ATOM 3643 O OD1 . ASN A 1 461 ? 19.158 -26.266 41.950 1.00 23.93 ? 461 ASN A OD1 1 ATOM 3644 N ND2 . ASN A 1 461 ? 21.220 -25.866 41.075 1.00 20.37 ? 461 ASN A ND2 1 ATOM 3645 N N . ASN A 1 462 ? 18.675 -28.107 44.673 1.00 22.76 ? 462 ASN A N 1 ATOM 3646 C CA . ASN A 1 462 ? 17.393 -27.936 45.367 1.00 24.04 ? 462 ASN A CA 1 ATOM 3647 C C . ASN A 1 462 ? 16.440 -26.870 44.779 1.00 22.91 ? 462 ASN A C 1 ATOM 3648 O O . ASN A 1 462 ? 15.248 -26.837 45.123 1.00 23.51 ? 462 ASN A O 1 ATOM 3649 C CB . ASN A 1 462 ? 17.613 -27.683 46.861 1.00 24.96 ? 462 ASN A CB 1 ATOM 3650 C CG . ASN A 1 462 ? 18.279 -26.349 47.141 1.00 29.07 ? 462 ASN A CG 1 ATOM 3651 O OD1 . ASN A 1 462 ? 19.424 -26.096 46.709 1.00 30.86 ? 462 ASN A OD1 1 ATOM 3652 N ND2 . ASN A 1 462 ? 17.575 -25.480 47.894 1.00 32.72 ? 462 ASN A ND2 1 ATOM 3653 N N . LEU A 1 463 ? 16.975 -25.986 43.941 1.00 21.89 ? 463 LEU A N 1 ATOM 3654 C CA . LEU A 1 463 ? 16.173 -24.945 43.279 1.00 21.71 ? 463 LEU A CA 1 ATOM 3655 C C . LEU A 1 463 ? 15.516 -25.544 42.047 1.00 21.27 ? 463 LEU A C 1 ATOM 3656 O O . LEU A 1 463 ? 14.279 -25.469 41.878 1.00 20.17 ? 463 LEU A O 1 ATOM 3657 C CB . LEU A 1 463 ? 17.016 -23.709 42.922 1.00 21.17 ? 463 LEU A CB 1 ATOM 3658 C CG . LEU A 1 463 ? 17.585 -22.929 44.120 1.00 22.26 ? 463 LEU A CG 1 ATOM 3659 C CD1 . LEU A 1 463 ? 18.030 -21.517 43.717 1.00 20.21 ? 463 LEU A CD1 1 ATOM 3660 C CD2 . LEU A 1 463 ? 16.546 -22.832 45.234 1.00 22.15 ? 463 LEU A CD2 1 ATOM 3661 N N . ASN A 1 464 ? 16.334 -26.211 41.231 1.00 19.88 ? 464 ASN A N 1 ATOM 3662 C CA . ASN A 1 464 ? 15.859 -26.845 39.987 1.00 19.80 ? 464 ASN A CA 1 ATOM 3663 C C . ASN A 1 464 ? 15.098 -28.106 40.270 1.00 18.71 ? 464 ASN A C 1 ATOM 3664 O O . ASN A 1 464 ? 14.215 -28.498 39.520 1.00 18.49 ? 464 ASN A O 1 ATOM 3665 C CB . ASN A 1 464 ? 17.036 -27.167 39.048 1.00 18.61 ? 464 ASN A CB 1 ATOM 3666 C CG . ASN A 1 464 ? 17.628 -25.943 38.420 1.00 21.36 ? 464 ASN A CG 1 ATOM 3667 O OD1 . ASN A 1 464 ? 18.875 -25.793 38.337 1.00 22.53 ? 464 ASN A OD1 1 ATOM 3668 N ND2 . ASN A 1 464 ? 16.760 -25.053 37.936 1.00 18.27 ? 464 ASN A ND2 1 ATOM 3669 N N . ASN A 1 465 ? 15.464 -28.751 41.366 1.00 19.49 ? 465 ASN A N 1 ATOM 3670 C CA . ASN A 1 465 ? 14.847 -30.006 41.764 1.00 20.03 ? 465 ASN A CA 1 ATOM 3671 C C . ASN A 1 465 ? 14.499 -30.002 43.252 1.00 20.01 ? 465 ASN A C 1 ATOM 3672 O O . ASN A 1 465 ? 15.192 -30.619 44.050 1.00 20.08 ? 465 ASN A O 1 ATOM 3673 C CB . ASN A 1 465 ? 15.714 -31.224 41.355 1.00 20.21 ? 465 ASN A CB 1 ATOM 3674 C CG . ASN A 1 465 ? 16.074 -31.218 39.870 1.00 21.34 ? 465 ASN A CG 1 ATOM 3675 O OD1 . ASN A 1 465 ? 15.404 -31.854 39.042 1.00 22.91 ? 465 ASN A OD1 1 ATOM 3676 N ND2 . ASN A 1 465 ? 17.131 -30.493 39.525 1.00 20.04 ? 465 ASN A ND2 1 ATOM 3677 N N . PRO A 1 466 ? 13.376 -29.322 43.625 1.00 19.92 ? 466 PRO A N 1 ATOM 3678 C CA . PRO A 1 466 ? 13.062 -29.108 45.042 1.00 19.33 ? 466 PRO A CA 1 ATOM 3679 C C . PRO A 1 466 ? 12.498 -30.353 45.730 1.00 19.37 ? 466 PRO A C 1 ATOM 3680 O O . PRO A 1 466 ? 12.062 -31.298 45.039 1.00 19.77 ? 466 PRO A O 1 ATOM 3681 C CB . PRO A 1 466 ? 12.004 -27.974 44.994 1.00 19.66 ? 466 PRO A CB 1 ATOM 3682 C CG . PRO A 1 466 ? 11.297 -28.177 43.691 1.00 19.12 ? 466 PRO A CG 1 ATOM 3683 C CD . PRO A 1 466 ? 12.347 -28.733 42.729 1.00 19.81 ? 466 PRO A CD 1 ATOM 3684 N N . PRO A 1 467 ? 12.468 -30.363 47.085 1.00 18.81 ? 467 PRO A N 1 ATOM 3685 C CA . PRO A 1 467 ? 11.955 -31.561 47.765 1.00 18.54 ? 467 PRO A CA 1 ATOM 3686 C C . PRO A 1 467 ? 10.467 -31.826 47.432 1.00 19.20 ? 467 PRO A C 1 ATOM 3687 O O . PRO A 1 467 ? 10.033 -32.992 47.359 1.00 19.34 ? 467 PRO A O 1 ATOM 3688 C CB . PRO A 1 467 ? 12.107 -31.236 49.256 1.00 18.68 ? 467 PRO A CB 1 ATOM 3689 C CG . PRO A 1 467 ? 12.826 -29.957 49.350 1.00 19.48 ? 467 PRO A CG 1 ATOM 3690 C CD . PRO A 1 467 ? 12.865 -29.293 48.016 1.00 17.84 ? 467 PRO A CD 1 ATOM 3691 N N . PHE A 1 468 ? 9.696 -30.752 47.231 1.00 18.46 ? 468 PHE A N 1 ATOM 3692 C CA . PHE A 1 468 ? 8.295 -30.884 46.792 1.00 18.00 ? 468 PHE A CA 1 ATOM 3693 C C . PHE A 1 468 ? 8.035 -29.997 45.568 1.00 18.13 ? 468 PHE A C 1 ATOM 3694 O O . PHE A 1 468 ? 8.458 -28.832 45.526 1.00 17.27 ? 468 PHE A O 1 ATOM 3695 C CB . PHE A 1 468 ? 7.365 -30.498 47.935 1.00 17.78 ? 468 PHE A CB 1 ATOM 3696 C CG . PHE A 1 468 ? 5.907 -30.498 47.575 1.00 17.08 ? 468 PHE A CG 1 ATOM 3697 C CD1 . PHE A 1 468 ? 5.168 -31.662 47.662 1.00 17.70 ? 468 PHE A CD1 1 ATOM 3698 C CD2 . PHE A 1 468 ? 5.271 -29.321 47.153 1.00 17.74 ? 468 PHE A CD2 1 ATOM 3699 C CE1 . PHE A 1 468 ? 3.789 -31.659 47.354 1.00 21.60 ? 468 PHE A CE1 1 ATOM 3700 C CE2 . PHE A 1 468 ? 3.895 -29.306 46.847 1.00 17.40 ? 468 PHE A CE2 1 ATOM 3701 C CZ . PHE A 1 468 ? 3.169 -30.479 46.931 1.00 18.83 ? 468 PHE A CZ 1 ATOM 3702 N N . THR A 1 469 ? 7.337 -30.558 44.585 1.00 18.39 ? 469 THR A N 1 ATOM 3703 C CA . THR A 1 469 ? 6.941 -29.843 43.391 1.00 18.71 ? 469 THR A CA 1 ATOM 3704 C C . THR A 1 469 ? 5.402 -29.877 43.381 1.00 19.53 ? 469 THR A C 1 ATOM 3705 O O . THR A 1 469 ? 4.818 -30.970 43.494 1.00 18.09 ? 469 THR A O 1 ATOM 3706 C CB . THR A 1 469 ? 7.496 -30.521 42.101 1.00 20.76 ? 469 THR A CB 1 ATOM 3707 O OG1 . THR A 1 469 ? 8.916 -30.751 42.228 1.00 19.57 ? 469 THR A OG1 1 ATOM 3708 C CG2 . THR A 1 469 ? 7.235 -29.611 40.851 1.00 18.53 ? 469 THR A CG2 1 ATOM 3709 N N . PRO A 1 470 ? 4.743 -28.684 43.321 1.00 19.62 ? 470 PRO A N 1 ATOM 3710 C CA . PRO A 1 470 ? 3.268 -28.694 43.151 1.00 20.67 ? 470 PRO A CA 1 ATOM 3711 C C . PRO A 1 470 ? 2.966 -29.341 41.819 1.00 20.96 ? 470 PRO A C 1 ATOM 3712 O O . PRO A 1 470 ? 3.890 -29.559 41.051 1.00 21.23 ? 470 PRO A O 1 ATOM 3713 C CB . PRO A 1 470 ? 2.884 -27.214 43.113 1.00 20.04 ? 470 PRO A CB 1 ATOM 3714 C CG . PRO A 1 470 ? 4.038 -26.480 43.679 1.00 21.22 ? 470 PRO A CG 1 ATOM 3715 C CD . PRO A 1 470 ? 5.282 -27.313 43.411 1.00 19.39 ? 470 PRO A CD 1 ATOM 3716 N N . ARG A 1 471 ? 1.702 -29.652 41.544 1.00 21.60 ? 471 ARG A N 1 ATOM 3717 C CA . ARG A 1 471 ? 1.371 -30.403 40.348 1.00 22.42 ? 471 ARG A CA 1 ATOM 3718 C C . ARG A 1 471 ? 1.307 -29.502 39.120 1.00 21.90 ? 471 ARG A C 1 ATOM 3719 O O . ARG A 1 471 ? 0.352 -29.533 38.351 1.00 22.20 ? 471 ARG A O 1 ATOM 3720 C CB . ARG A 1 471 ? 0.070 -31.191 40.537 1.00 23.29 ? 471 ARG A CB 1 ATOM 3721 C CG . ARG A 1 471 ? -1.129 -30.331 40.840 1.00 26.50 ? 471 ARG A CG 1 ATOM 3722 C CD . ARG A 1 471 ? -2.386 -31.138 40.676 1.00 32.89 ? 471 ARG A CD 1 ATOM 3723 N NE . ARG A 1 471 ? -2.488 -32.191 41.685 1.00 34.98 ? 471 ARG A NE 1 ATOM 3724 C CZ . ARG A 1 471 ? -3.580 -32.926 41.889 1.00 36.80 ? 471 ARG A CZ 1 ATOM 3725 N NH1 . ARG A 1 471 ? -4.681 -32.726 41.151 1.00 34.20 ? 471 ARG A NH1 1 ATOM 3726 N NH2 . ARG A 1 471 ? -3.571 -33.849 42.848 1.00 38.06 ? 471 ARG A NH2 1 ATOM 3727 N N . ILE A 1 472 ? 2.356 -28.714 38.936 1.00 21.57 ? 472 ILE A N 1 ATOM 3728 C CA . ILE A 1 472 ? 2.514 -27.889 37.747 1.00 20.57 ? 472 ILE A CA 1 ATOM 3729 C C . ILE A 1 472 ? 2.655 -28.770 36.501 1.00 20.97 ? 472 ILE A C 1 ATOM 3730 O O . ILE A 1 472 ? 3.161 -29.910 36.581 1.00 20.77 ? 472 ILE A O 1 ATOM 3731 C CB . ILE A 1 472 ? 3.707 -26.913 37.913 1.00 20.33 ? 472 ILE A CB 1 ATOM 3732 C CG1 . ILE A 1 472 ? 5.014 -27.678 38.151 1.00 20.42 ? 472 ILE A CG1 1 ATOM 3733 C CG2 . ILE A 1 472 ? 3.426 -25.940 39.081 1.00 18.81 ? 472 ILE A CG2 1 ATOM 3734 C CD1 . ILE A 1 472 ? 6.281 -26.919 37.799 1.00 21.81 ? 472 ILE A CD1 1 ATOM 3735 N N . LEU A 1 473 ? 2.183 -28.256 35.359 1.00 20.60 ? 473 LEU A N 1 ATOM 3736 C CA . LEU A 1 473 ? 2.299 -28.935 34.081 1.00 20.25 ? 473 LEU A CA 1 ATOM 3737 C C . LEU A 1 473 ? 3.735 -29.421 33.885 1.00 20.56 ? 473 LEU A C 1 ATOM 3738 O O . LEU A 1 473 ? 4.684 -28.641 34.065 1.00 19.70 ? 473 LEU A O 1 ATOM 3739 C CB . LEU A 1 473 ? 1.928 -27.990 32.934 1.00 19.59 ? 473 LEU A CB 1 ATOM 3740 C CG . LEU A 1 473 ? 1.933 -28.633 31.522 1.00 20.82 ? 473 LEU A CG 1 ATOM 3741 C CD1 . LEU A 1 473 ? 1.128 -29.918 31.400 1.00 21.81 ? 473 LEU A CD1 1 ATOM 3742 C CD2 . LEU A 1 473 ? 1.509 -27.635 30.483 1.00 20.29 ? 473 LEU A CD2 1 ATOM 3743 N N . ASP A 1 474 ? 3.866 -30.698 33.524 1.00 21.06 ? 474 ASP A N 1 ATOM 3744 C CA . ASP A 1 474 ? 5.151 -31.382 33.286 1.00 21.75 ? 474 ASP A CA 1 ATOM 3745 C C . ASP A 1 474 ? 5.924 -31.791 34.541 1.00 21.10 ? 474 ASP A C 1 ATOM 3746 O O . ASP A 1 474 ? 6.780 -32.675 34.477 1.00 22.75 ? 474 ASP A O 1 ATOM 3747 C CB . ASP A 1 474 ? 6.050 -30.607 32.300 1.00 21.94 ? 474 ASP A CB 1 ATOM 3748 C CG . ASP A 1 474 ? 5.434 -30.489 30.919 1.00 25.40 ? 474 ASP A CG 1 ATOM 3749 O OD1 . ASP A 1 474 ? 4.660 -31.396 30.519 1.00 29.50 ? 474 ASP A OD1 1 ATOM 3750 O OD2 . ASP A 1 474 ? 5.720 -29.486 30.215 1.00 29.42 ? 474 ASP A OD2 1 ATOM 3751 N N . GLY A 1 475 ? 5.674 -31.121 35.662 1.00 20.70 ? 475 GLY A N 1 ATOM 3752 C CA . GLY A 1 475 ? 6.236 -31.499 36.956 1.00 19.94 ? 475 GLY A CA 1 ATOM 3753 C C . GLY A 1 475 ? 7.679 -31.073 37.230 1.00 20.09 ? 475 GLY A C 1 ATOM 3754 O O . GLY A 1 475 ? 8.293 -31.554 38.174 1.00 20.43 ? 475 GLY A O 1 ATOM 3755 N N . TYR A 1 476 ? 8.228 -30.188 36.409 1.00 19.63 ? 476 TYR A N 1 ATOM 3756 C CA . TYR A 1 476 ? 9.541 -29.582 36.693 1.00 20.42 ? 476 TYR A CA 1 ATOM 3757 C C . TYR A 1 476 ? 9.388 -28.090 36.554 1.00 19.97 ? 476 TYR A C 1 ATOM 3758 O O . TYR A 1 476 ? 8.788 -27.621 35.595 1.00 19.57 ? 476 TYR A O 1 ATOM 3759 C CB . TYR A 1 476 ? 10.647 -30.097 35.727 1.00 21.86 ? 476 TYR A CB 1 ATOM 3760 C CG . TYR A 1 476 ? 10.871 -31.589 35.819 1.00 22.47 ? 476 TYR A CG 1 ATOM 3761 C CD1 . TYR A 1 476 ? 11.966 -32.100 36.526 1.00 26.00 ? 476 TYR A CD1 1 ATOM 3762 C CD2 . TYR A 1 476 ? 10.006 -32.490 35.199 1.00 22.73 ? 476 TYR A CD2 1 ATOM 3763 C CE1 . TYR A 1 476 ? 12.171 -33.461 36.633 1.00 25.16 ? 476 TYR A CE1 1 ATOM 3764 C CE2 . TYR A 1 476 ? 10.198 -33.866 35.311 1.00 23.51 ? 476 TYR A CE2 1 ATOM 3765 C CZ . TYR A 1 476 ? 11.292 -34.338 36.028 1.00 25.14 ? 476 TYR A CZ 1 ATOM 3766 O OH . TYR A 1 476 ? 11.526 -35.702 36.149 1.00 26.25 ? 476 TYR A OH 1 ATOM 3767 N N . LEU A 1 477 ? 9.936 -27.350 37.512 1.00 19.92 ? 477 LEU A N 1 ATOM 3768 C CA . LEU A 1 477 ? 9.870 -25.888 37.519 1.00 20.15 ? 477 LEU A CA 1 ATOM 3769 C C . LEU A 1 477 ? 10.430 -25.231 36.272 1.00 20.55 ? 477 LEU A C 1 ATOM 3770 O O . LEU A 1 477 ? 9.878 -24.236 35.787 1.00 20.07 ? 477 LEU A O 1 ATOM 3771 C CB . LEU A 1 477 ? 10.576 -25.318 38.754 1.00 19.33 ? 477 LEU A CB 1 ATOM 3772 C CG . LEU A 1 477 ? 9.939 -25.709 40.089 1.00 19.41 ? 477 LEU A CG 1 ATOM 3773 C CD1 . LEU A 1 477 ? 10.850 -25.338 41.255 1.00 16.64 ? 477 LEU A CD1 1 ATOM 3774 C CD2 . LEU A 1 477 ? 8.532 -25.080 40.233 1.00 16.01 ? 477 LEU A CD2 1 ATOM 3775 N N . PHE A 1 478 ? 11.525 -25.784 35.752 1.00 20.46 ? 478 PHE A N 1 ATOM 3776 C CA . PHE A 1 478 ? 12.246 -25.120 34.676 1.00 20.27 ? 478 PHE A CA 1 ATOM 3777 C C . PHE A 1 478 ? 11.684 -25.394 33.302 1.00 19.89 ? 478 PHE A C 1 ATOM 3778 O O . PHE A 1 478 ? 12.182 -24.858 32.337 1.00 19.48 ? 478 PHE A O 1 ATOM 3779 C CB . PHE A 1 478 ? 13.714 -25.526 34.700 1.00 20.88 ? 478 PHE A CB 1 ATOM 3780 C CG . PHE A 1 478 ? 13.918 -26.990 34.871 1.00 19.77 ? 478 PHE A CG 1 ATOM 3781 C CD1 . PHE A 1 478 ? 13.906 -27.838 33.780 1.00 20.23 ? 478 PHE A CD1 1 ATOM 3782 C CD2 . PHE A 1 478 ? 14.116 -27.524 36.132 1.00 17.71 ? 478 PHE A CD2 1 ATOM 3783 C CE1 . PHE A 1 478 ? 14.069 -29.206 33.958 1.00 19.42 ? 478 PHE A CE1 1 ATOM 3784 C CE2 . PHE A 1 478 ? 14.292 -28.882 36.300 1.00 18.78 ? 478 PHE A CE2 1 ATOM 3785 C CZ . PHE A 1 478 ? 14.266 -29.716 35.210 1.00 16.85 ? 478 PHE A CZ 1 ATOM 3786 N N . CYS A 1 479 ? 10.689 -26.267 33.201 1.00 20.78 ? 479 CYS A N 1 ATOM 3787 C CA . CYS A 1 479 ? 10.089 -26.584 31.901 1.00 22.64 ? 479 CYS A CA 1 ATOM 3788 C C . CYS A 1 479 ? 9.633 -25.339 31.196 1.00 21.59 ? 479 CYS A C 1 ATOM 3789 O O . CYS A 1 479 ? 8.891 -24.543 31.756 1.00 22.14 ? 479 CYS A O 1 ATOM 3790 C CB . CYS A 1 479 ? 8.915 -27.560 32.016 1.00 23.02 ? 479 CYS A CB 1 ATOM 3791 S SG . CYS A 1 479 ? 9.424 -29.167 32.510 1.00 31.97 ? 479 CYS A SG 1 ATOM 3792 N N . LYS A 1 480 ? 10.110 -25.196 29.964 1.00 21.39 ? 480 LYS A N 1 ATOM 3793 C CA . LYS A 1 480 ? 9.825 -24.078 29.076 1.00 20.90 ? 480 LYS A CA 1 ATOM 3794 C C . LYS A 1 480 ? 10.070 -22.702 29.708 1.00 19.98 ? 480 LYS A C 1 ATOM 3795 O O . LYS A 1 480 ? 9.377 -21.737 29.398 1.00 19.30 ? 480 LYS A O 1 ATOM 3796 C CB . LYS A 1 480 ? 8.399 -24.202 28.509 1.00 22.16 ? 480 LYS A CB 1 ATOM 3797 C CG . LYS A 1 480 ? 8.106 -25.543 27.794 1.00 22.28 ? 480 LYS A CG 1 ATOM 3798 C CD . LYS A 1 480 ? 9.058 -25.806 26.613 1.00 24.85 ? 480 LYS A CD 1 ATOM 3799 C CE . LYS A 1 480 ? 8.908 -27.233 26.050 1.00 27.05 ? 480 LYS A CE 1 ATOM 3800 N NZ . LYS A 1 480 ? 10.261 -27.855 25.745 1.00 31.97 ? 480 LYS A NZ 1 ATOM 3801 N N . THR A 1 481 ? 11.043 -22.609 30.611 1.00 18.10 ? 481 THR A N 1 ATOM 3802 C CA . THR A 1 481 ? 11.376 -21.308 31.184 1.00 16.52 ? 481 THR A CA 1 ATOM 3803 C C . THR A 1 481 ? 12.861 -21.297 31.570 1.00 16.82 ? 481 THR A C 1 ATOM 3804 O O . THR A 1 481 ? 13.626 -22.061 30.998 1.00 16.37 ? 481 THR A O 1 ATOM 3805 C CB . THR A 1 481 ? 10.384 -20.839 32.327 1.00 15.16 ? 481 THR A CB 1 ATOM 3806 O OG1 . THR A 1 481 ? 10.698 -19.504 32.718 1.00 13.83 ? 481 THR A OG1 1 ATOM 3807 C CG2 . THR A 1 481 ? 10.436 -21.716 33.544 1.00 14.69 ? 481 THR A CG2 1 ATOM 3808 N N . LEU A 1 482 ? 13.278 -20.423 32.485 1.00 17.31 ? 482 LEU A N 1 ATOM 3809 C CA . LEU A 1 482 ? 14.716 -20.340 32.830 1.00 18.41 ? 482 LEU A CA 1 ATOM 3810 C C . LEU A 1 482 ? 15.045 -21.269 33.998 1.00 19.11 ? 482 LEU A C 1 ATOM 3811 O O . LEU A 1 482 ? 14.147 -21.693 34.743 1.00 19.22 ? 482 LEU A O 1 ATOM 3812 C CB . LEU A 1 482 ? 15.129 -18.894 33.148 1.00 18.09 ? 482 LEU A CB 1 ATOM 3813 C CG . LEU A 1 482 ? 14.676 -17.786 32.185 1.00 20.15 ? 482 LEU A CG 1 ATOM 3814 C CD1 . LEU A 1 482 ? 15.191 -16.418 32.628 1.00 21.44 ? 482 LEU A CD1 1 ATOM 3815 C CD2 . LEU A 1 482 ? 15.127 -18.093 30.776 1.00 22.53 ? 482 LEU A CD2 1 ATOM 3816 N N . CYS A 1 483 ? 16.331 -21.626 34.141 1.00 19.93 ? 483 CYS A N 1 ATOM 3817 C CA . CYS A 1 483 ? 16.810 -22.279 35.340 1.00 19.91 ? 483 CYS A CA 1 ATOM 3818 C C . CYS A 1 483 ? 16.330 -21.495 36.571 1.00 19.60 ? 483 CYS A C 1 ATOM 3819 O O . CYS A 1 483 ? 16.384 -20.257 36.603 1.00 20.04 ? 483 CYS A O 1 ATOM 3820 C CB . CYS A 1 483 ? 18.354 -22.305 35.339 1.00 21.18 ? 483 CYS A CB 1 ATOM 3821 S SG . CYS A 1 483 ? 19.036 -23.073 33.882 1.00 27.19 ? 483 CYS A SG 1 ATOM 3822 N N . MET A 1 484 ? 15.844 -22.232 37.569 1.00 18.77 ? 484 MET A N 1 ATOM 3823 C CA . MET A 1 484 ? 15.474 -21.705 38.883 1.00 17.55 ? 484 MET A CA 1 ATOM 3824 C C . MET A 1 484 ? 16.660 -21.086 39.637 1.00 17.64 ? 484 MET A C 1 ATOM 3825 O O . MET A 1 484 ? 16.474 -20.250 40.503 1.00 16.48 ? 484 MET A O 1 ATOM 3826 C CB . MET A 1 484 ? 14.833 -22.827 39.697 1.00 17.96 ? 484 MET A CB 1 ATOM 3827 C CG . MET A 1 484 ? 13.513 -23.335 39.055 1.00 17.86 ? 484 MET A CG 1 ATOM 3828 S SD . MET A 1 484 ? 12.376 -21.920 39.099 1.00 24.36 ? 484 MET A SD 1 ATOM 3829 C CE . MET A 1 484 ? 11.905 -21.751 37.384 1.00 21.86 ? 484 MET A CE 1 ATOM 3830 N N . ASP A 1 485 ? 17.883 -21.486 39.301 1.00 17.30 ? 485 ASP A N 1 ATOM 3831 C CA . ASP A 1 485 ? 19.039 -20.826 39.920 1.00 17.22 ? 485 ASP A CA 1 ATOM 3832 C C . ASP A 1 485 ? 19.573 -19.619 39.117 1.00 17.56 ? 485 ASP A C 1 ATOM 3833 O O . ASP A 1 485 ? 20.546 -18.963 39.526 1.00 15.76 ? 485 ASP A O 1 ATOM 3834 C CB . ASP A 1 485 ? 20.127 -21.834 40.318 1.00 17.88 ? 485 ASP A CB 1 ATOM 3835 C CG . ASP A 1 485 ? 20.567 -22.751 39.180 1.00 17.42 ? 485 ASP A CG 1 ATOM 3836 O OD1 . ASP A 1 485 ? 20.179 -22.516 38.027 1.00 15.63 ? 485 ASP A OD1 1 ATOM 3837 O OD2 . ASP A 1 485 ? 21.335 -23.725 39.451 1.00 18.63 ? 485 ASP A OD2 1 ATOM 3838 N N . ALA A 1 486 ? 18.900 -19.292 38.004 1.00 17.79 ? 486 ALA A N 1 ATOM 3839 C CA . ALA A 1 486 ? 19.166 -18.042 37.293 1.00 18.95 ? 486 ALA A CA 1 ATOM 3840 C C . ALA A 1 486 ? 19.013 -16.846 38.236 1.00 20.06 ? 486 ALA A C 1 ATOM 3841 O O . ALA A 1 486 ? 18.240 -16.895 39.204 1.00 19.66 ? 486 ALA A O 1 ATOM 3842 C CB . ALA A 1 486 ? 18.275 -17.886 36.082 1.00 20.09 ? 486 ALA A CB 1 ATOM 3843 N N . VAL A 1 487 ? 19.787 -15.791 37.958 1.00 19.85 ? 487 VAL A N 1 ATOM 3844 C CA . VAL A 1 487 ? 19.968 -14.691 38.878 1.00 19.56 ? 487 VAL A CA 1 ATOM 3845 C C . VAL A 1 487 ? 19.603 -13.343 38.252 1.00 18.88 ? 487 VAL A C 1 ATOM 3846 O O . VAL A 1 487 ? 19.913 -13.047 37.107 1.00 18.66 ? 487 VAL A O 1 ATOM 3847 C CB . VAL A 1 487 ? 21.433 -14.732 39.471 1.00 20.31 ? 487 VAL A CB 1 ATOM 3848 C CG1 . VAL A 1 487 ? 21.978 -13.380 39.677 1.00 20.62 ? 487 VAL A CG1 1 ATOM 3849 C CG2 . VAL A 1 487 ? 21.425 -15.533 40.793 1.00 20.24 ? 487 VAL A CG2 1 ATOM 3850 N N . GLN A 1 488 ? 18.909 -12.536 39.038 1.00 19.10 ? 488 GLN A N 1 ATOM 3851 C CA . GLN A 1 488 ? 18.343 -11.284 38.596 1.00 19.46 ? 488 GLN A CA 1 ATOM 3852 C C . GLN A 1 488 ? 18.483 -10.315 39.754 1.00 19.75 ? 488 GLN A C 1 ATOM 3853 O O . GLN A 1 488 ? 18.780 -10.724 40.877 1.00 19.49 ? 488 GLN A O 1 ATOM 3854 C CB . GLN A 1 488 ? 16.860 -11.481 38.280 1.00 19.65 ? 488 GLN A CB 1 ATOM 3855 C CG . GLN A 1 488 ? 16.590 -11.921 36.881 1.00 19.25 ? 488 GLN A CG 1 ATOM 3856 C CD . GLN A 1 488 ? 15.101 -11.921 36.537 1.00 22.48 ? 488 GLN A CD 1 ATOM 3857 O OE1 . GLN A 1 488 ? 14.582 -10.966 35.955 1.00 24.35 ? 488 GLN A OE1 1 ATOM 3858 N NE2 . GLN A 1 488 ? 14.431 -13.000 36.860 1.00 19.87 ? 488 GLN A NE2 1 ATOM 3859 N N . HIS A 1 489 ? 18.239 -9.039 39.498 1.00 20.58 ? 489 HIS A N 1 ATOM 3860 C CA . HIS A 1 489 ? 18.321 -8.027 40.559 1.00 21.26 ? 489 HIS A CA 1 ATOM 3861 C C . HIS A 1 489 ? 17.492 -8.326 41.841 1.00 21.42 ? 489 HIS A C 1 ATOM 3862 O O . HIS A 1 489 ? 18.028 -8.245 42.962 1.00 19.71 ? 489 HIS A O 1 ATOM 3863 C CB . HIS A 1 489 ? 17.997 -6.641 40.005 1.00 21.68 ? 489 HIS A CB 1 ATOM 3864 C CG . HIS A 1 489 ? 18.262 -5.550 40.984 1.00 24.60 ? 489 HIS A CG 1 ATOM 3865 N ND1 . HIS A 1 489 ? 17.290 -4.669 41.393 1.00 24.86 ? 489 HIS A ND1 1 ATOM 3866 C CD2 . HIS A 1 489 ? 19.380 -5.236 41.686 1.00 26.49 ? 489 HIS A CD2 1 ATOM 3867 C CE1 . HIS A 1 489 ? 17.799 -3.841 42.289 1.00 27.31 ? 489 HIS A CE1 1 ATOM 3868 N NE2 . HIS A 1 489 ? 19.067 -4.168 42.489 1.00 27.60 ? 489 HIS A NE2 1 ATOM 3869 N N . TRP A 1 490 ? 16.208 -8.696 41.667 1.00 21.38 ? 490 TRP A N 1 ATOM 3870 C CA . TRP A 1 490 ? 15.326 -8.995 42.799 1.00 22.08 ? 490 TRP A CA 1 ATOM 3871 C C . TRP A 1 490 ? 15.552 -10.366 43.436 1.00 22.37 ? 490 TRP A C 1 ATOM 3872 O O . TRP A 1 490 ? 15.006 -10.649 44.507 1.00 23.02 ? 490 TRP A O 1 ATOM 3873 C CB . TRP A 1 490 ? 13.832 -8.892 42.421 1.00 22.03 ? 490 TRP A CB 1 ATOM 3874 C CG . TRP A 1 490 ? 13.297 -7.532 42.181 1.00 22.16 ? 490 TRP A CG 1 ATOM 3875 C CD1 . TRP A 1 490 ? 13.934 -6.327 42.381 1.00 21.96 ? 490 TRP A CD1 1 ATOM 3876 C CD2 . TRP A 1 490 ? 11.975 -7.215 41.726 1.00 22.38 ? 490 TRP A CD2 1 ATOM 3877 N NE1 . TRP A 1 490 ? 13.096 -5.299 42.047 1.00 22.08 ? 490 TRP A NE1 1 ATOM 3878 C CE2 . TRP A 1 490 ? 11.889 -5.816 41.642 1.00 23.40 ? 490 TRP A CE2 1 ATOM 3879 C CE3 . TRP A 1 490 ? 10.860 -7.991 41.356 1.00 24.23 ? 490 TRP A CE3 1 ATOM 3880 C CZ2 . TRP A 1 490 ? 10.723 -5.161 41.208 1.00 23.75 ? 490 TRP A CZ2 1 ATOM 3881 C CZ3 . TRP A 1 490 ? 9.700 -7.344 40.938 1.00 22.77 ? 490 TRP A CZ3 1 ATOM 3882 C CH2 . TRP A 1 490 ? 9.648 -5.935 40.875 1.00 23.21 ? 490 TRP A CH2 1 ATOM 3883 N N . GLY A 1 491 ? 16.277 -11.246 42.748 1.00 22.97 ? 491 GLY A N 1 ATOM 3884 C CA . GLY A 1 491 ? 16.771 -12.484 43.355 1.00 22.31 ? 491 GLY A CA 1 ATOM 3885 C C . GLY A 1 491 ? 16.929 -13.643 42.393 1.00 21.66 ? 491 GLY A C 1 ATOM 3886 O O . GLY A 1 491 ? 17.087 -13.453 41.198 1.00 21.86 ? 491 GLY A O 1 ATOM 3887 N N . LYS A 1 492 ? 16.884 -14.852 42.931 1.00 21.66 ? 492 LYS A N 1 ATOM 3888 C CA . LYS A 1 492 ? 16.961 -16.062 42.122 1.00 21.45 ? 492 LYS A CA 1 ATOM 3889 C C . LYS A 1 492 ? 15.602 -16.356 41.476 1.00 20.94 ? 492 LYS A C 1 ATOM 3890 O O . LYS A 1 492 ? 14.565 -16.059 42.056 1.00 19.43 ? 492 LYS A O 1 ATOM 3891 C CB . LYS A 1 492 ? 17.471 -17.239 42.967 1.00 21.59 ? 492 LYS A CB 1 ATOM 3892 C CG . LYS A 1 492 ? 18.927 -17.039 43.439 1.00 25.42 ? 492 LYS A CG 1 ATOM 3893 C CD . LYS A 1 492 ? 19.742 -18.330 43.396 1.00 29.15 ? 492 LYS A CD 1 ATOM 3894 C CE . LYS A 1 492 ? 21.262 -18.049 43.310 1.00 31.67 ? 492 LYS A CE 1 ATOM 3895 N NZ . LYS A 1 492 ? 21.883 -18.912 42.240 1.00 32.75 ? 492 LYS A NZ 1 ATOM 3896 N N . GLN A 1 493 ? 15.641 -16.905 40.267 1.00 19.76 ? 493 GLN A N 1 ATOM 3897 C CA . GLN A 1 493 ? 14.455 -17.217 39.492 1.00 20.41 ? 493 GLN A CA 1 ATOM 3898 C C . GLN A 1 493 ? 13.412 -18.063 40.266 1.00 19.78 ? 493 GLN A C 1 ATOM 3899 O O . GLN A 1 493 ? 12.226 -17.847 40.105 1.00 18.24 ? 493 GLN A O 1 ATOM 3900 C CB . GLN A 1 493 ? 14.890 -17.878 38.190 1.00 20.79 ? 493 GLN A CB 1 ATOM 3901 C CG . GLN A 1 493 ? 13.808 -18.441 37.319 1.00 21.42 ? 493 GLN A CG 1 ATOM 3902 C CD . GLN A 1 493 ? 13.106 -17.411 36.436 1.00 22.54 ? 493 GLN A CD 1 ATOM 3903 O OE1 . GLN A 1 493 ? 13.368 -16.202 36.473 1.00 22.78 ? 493 GLN A OE1 1 ATOM 3904 N NE2 . GLN A 1 493 ? 12.202 -17.908 35.634 1.00 22.45 ? 493 GLN A NE2 1 ATOM 3905 N N . TYR A 1 494 ? 13.881 -19.009 41.084 1.00 18.06 ? 494 TYR A N 1 ATOM 3906 C CA . TYR A 1 494 ? 13.057 -19.771 42.028 1.00 18.54 ? 494 TYR A CA 1 ATOM 3907 C C . TYR A 1 494 ? 12.042 -18.917 42.787 1.00 19.36 ? 494 TYR A C 1 ATOM 3908 O O . TYR A 1 494 ? 10.929 -19.373 43.049 1.00 17.97 ? 494 TYR A O 1 ATOM 3909 C CB . TYR A 1 494 ? 13.921 -20.428 43.094 1.00 16.88 ? 494 TYR A CB 1 ATOM 3910 C CG . TYR A 1 494 ? 13.234 -21.453 43.955 1.00 17.23 ? 494 TYR A CG 1 ATOM 3911 C CD1 . TYR A 1 494 ? 12.977 -22.751 43.475 1.00 14.84 ? 494 TYR A CD1 1 ATOM 3912 C CD2 . TYR A 1 494 ? 12.853 -21.144 45.262 1.00 15.96 ? 494 TYR A CD2 1 ATOM 3913 C CE1 . TYR A 1 494 ? 12.378 -23.731 44.279 1.00 13.89 ? 494 TYR A CE1 1 ATOM 3914 C CE2 . TYR A 1 494 ? 12.214 -22.093 46.055 1.00 17.20 ? 494 TYR A CE2 1 ATOM 3915 C CZ . TYR A 1 494 ? 11.979 -23.383 45.563 1.00 15.79 ? 494 TYR A CZ 1 ATOM 3916 O OH . TYR A 1 494 ? 11.381 -24.304 46.395 1.00 15.60 ? 494 TYR A OH 1 ATOM 3917 N N . ASP A 1 495 ? 12.505 -17.747 43.221 1.00 19.15 ? 495 ASP A N 1 ATOM 3918 C CA . ASP A 1 495 ? 11.713 -16.837 44.017 1.00 20.05 ? 495 ASP A CA 1 ATOM 3919 C C . ASP A 1 495 ? 10.935 -15.842 43.159 1.00 20.53 ? 495 ASP A C 1 ATOM 3920 O O . ASP A 1 495 ? 9.809 -15.488 43.508 1.00 19.47 ? 495 ASP A O 1 ATOM 3921 C CB . ASP A 1 495 ? 12.593 -16.083 45.015 1.00 19.95 ? 495 ASP A CB 1 ATOM 3922 C CG . ASP A 1 495 ? 13.091 -16.971 46.142 1.00 22.17 ? 495 ASP A CG 1 ATOM 3923 O OD1 . ASP A 1 495 ? 12.299 -17.828 46.657 1.00 24.09 ? 495 ASP A OD1 1 ATOM 3924 O OD2 . ASP A 1 495 ? 14.263 -16.768 46.543 1.00 21.93 ? 495 ASP A OD2 1 ATOM 3925 N N . ILE A 1 496 ? 11.526 -15.398 42.042 1.00 19.53 ? 496 ILE A N 1 ATOM 3926 C CA . ILE A 1 496 ? 10.935 -14.272 41.297 1.00 19.66 ? 496 ILE A CA 1 ATOM 3927 C C . ILE A 1 496 ? 10.406 -14.624 39.924 1.00 17.99 ? 496 ILE A C 1 ATOM 3928 O O . ILE A 1 496 ? 10.047 -13.735 39.184 1.00 18.09 ? 496 ILE A O 1 ATOM 3929 C CB . ILE A 1 496 ? 11.903 -13.087 41.178 1.00 20.33 ? 496 ILE A CB 1 ATOM 3930 C CG1 . ILE A 1 496 ? 13.022 -13.392 40.181 1.00 21.86 ? 496 ILE A CG1 1 ATOM 3931 C CG2 . ILE A 1 496 ? 12.435 -12.664 42.575 1.00 20.75 ? 496 ILE A CG2 1 ATOM 3932 C CD1 . ILE A 1 496 ? 14.022 -12.256 40.110 1.00 23.99 ? 496 ILE A CD1 1 ATOM 3933 N N . HIS A 1 497 ? 10.351 -15.919 39.600 1.00 16.98 ? 497 HIS A N 1 ATOM 3934 C CA . HIS A 1 497 ? 9.841 -16.370 38.311 1.00 17.06 ? 497 HIS A CA 1 ATOM 3935 C C . HIS A 1 497 ? 8.457 -15.756 38.015 1.00 16.54 ? 497 HIS A C 1 ATOM 3936 O O . HIS A 1 497 ? 8.242 -15.189 36.935 1.00 17.84 ? 497 HIS A O 1 ATOM 3937 C CB . HIS A 1 497 ? 9.764 -17.895 38.265 1.00 16.38 ? 497 HIS A CB 1 ATOM 3938 C CG . HIS A 1 497 ? 9.038 -18.437 37.071 1.00 16.41 ? 497 HIS A CG 1 ATOM 3939 N ND1 . HIS A 1 497 ? 7.673 -18.649 37.069 1.00 17.29 ? 497 HIS A ND1 1 ATOM 3940 C CD2 . HIS A 1 497 ? 9.479 -18.819 35.853 1.00 13.67 ? 497 HIS A CD2 1 ATOM 3941 C CE1 . HIS A 1 497 ? 7.307 -19.121 35.898 1.00 15.08 ? 497 HIS A CE1 1 ATOM 3942 N NE2 . HIS A 1 497 ? 8.383 -19.245 35.146 1.00 19.04 ? 497 HIS A NE2 1 ATOM 3943 N N . ASN A 1 498 ? 7.536 -15.889 38.961 1.00 16.83 ? 498 ASN A N 1 ATOM 3944 C CA . ASN A 1 498 ? 6.161 -15.407 38.795 1.00 17.33 ? 498 ASN A CA 1 ATOM 3945 C C . ASN A 1 498 ? 6.093 -13.877 38.624 1.00 18.03 ? 498 ASN A C 1 ATOM 3946 O O . ASN A 1 498 ? 5.059 -13.332 38.276 1.00 18.72 ? 498 ASN A O 1 ATOM 3947 C CB . ASN A 1 498 ? 5.278 -15.888 39.972 1.00 16.72 ? 498 ASN A CB 1 ATOM 3948 C CG . ASN A 1 498 ? 4.826 -17.329 39.828 1.00 16.36 ? 498 ASN A CG 1 ATOM 3949 O OD1 . ASN A 1 498 ? 4.291 -17.922 40.758 1.00 20.93 ? 498 ASN A OD1 1 ATOM 3950 N ND2 . ASN A 1 498 ? 4.992 -17.884 38.654 1.00 18.33 ? 498 ASN A ND2 1 ATOM 3951 N N . LEU A 1 499 ? 7.229 -13.199 38.820 1.00 18.71 ? 499 LEU A N 1 ATOM 3952 C CA . LEU A 1 499 ? 7.284 -11.747 38.749 1.00 19.15 ? 499 LEU A CA 1 ATOM 3953 C C . LEU A 1 499 ? 7.862 -11.188 37.471 1.00 19.46 ? 499 LEU A C 1 ATOM 3954 O O . LEU A 1 499 ? 7.988 -9.980 37.364 1.00 20.35 ? 499 LEU A O 1 ATOM 3955 C CB . LEU A 1 499 ? 8.091 -11.192 39.939 1.00 20.00 ? 499 LEU A CB 1 ATOM 3956 C CG . LEU A 1 499 ? 7.579 -11.544 41.333 1.00 20.38 ? 499 LEU A CG 1 ATOM 3957 C CD1 . LEU A 1 499 ? 8.475 -10.969 42.444 1.00 17.76 ? 499 LEU A CD1 1 ATOM 3958 C CD2 . LEU A 1 499 ? 6.117 -11.072 41.469 1.00 17.73 ? 499 LEU A CD2 1 ATOM 3959 N N . TYR A 1 500 ? 8.250 -12.045 36.514 1.00 18.97 ? 500 TYR A N 1 ATOM 3960 C CA . TYR A 1 500 ? 8.884 -11.561 35.284 1.00 17.90 ? 500 TYR A CA 1 ATOM 3961 C C . TYR A 1 500 ? 7.899 -10.721 34.429 1.00 17.64 ? 500 TYR A C 1 ATOM 3962 O O . TYR A 1 500 ? 8.227 -9.622 33.969 1.00 19.23 ? 500 TYR A O 1 ATOM 3963 C CB . TYR A 1 500 ? 9.420 -12.734 34.451 1.00 17.04 ? 500 TYR A CB 1 ATOM 3964 C CG . TYR A 1 500 ? 10.347 -12.292 33.334 1.00 17.66 ? 500 TYR A CG 1 ATOM 3965 C CD1 . TYR A 1 500 ? 11.717 -12.396 33.484 1.00 17.17 ? 500 TYR A CD1 1 ATOM 3966 C CD2 . TYR A 1 500 ? 9.853 -11.759 32.148 1.00 12.83 ? 500 TYR A CD2 1 ATOM 3967 C CE1 . TYR A 1 500 ? 12.600 -11.976 32.457 1.00 17.32 ? 500 TYR A CE1 1 ATOM 3968 C CE2 . TYR A 1 500 ? 10.694 -11.335 31.142 1.00 14.85 ? 500 TYR A CE2 1 ATOM 3969 C CZ . TYR A 1 500 ? 12.082 -11.455 31.309 1.00 17.12 ? 500 TYR A CZ 1 ATOM 3970 O OH . TYR A 1 500 ? 12.924 -11.059 30.301 1.00 19.32 ? 500 TYR A OH 1 ATOM 3971 N N . GLY A 1 501 ? 6.704 -11.248 34.184 1.00 16.66 ? 501 GLY A N 1 ATOM 3972 C CA . GLY A 1 501 ? 5.708 -10.501 33.395 1.00 15.75 ? 501 GLY A CA 1 ATOM 3973 C C . GLY A 1 501 ? 5.286 -9.218 34.054 1.00 14.27 ? 501 GLY A C 1 ATOM 3974 O O . GLY A 1 501 ? 5.208 -8.179 33.422 1.00 15.44 ? 501 GLY A O 1 ATOM 3975 N N . TYR A 1 502 ? 5.067 -9.273 35.352 1.00 14.80 ? 502 TYR A N 1 ATOM 3976 C CA . TYR A 1 502 ? 4.810 -8.061 36.146 1.00 15.80 ? 502 TYR A CA 1 ATOM 3977 C C . TYR A 1 502 ? 5.951 -6.996 36.015 1.00 16.16 ? 502 TYR A C 1 ATOM 3978 O O . TYR A 1 502 ? 5.719 -5.817 35.690 1.00 15.78 ? 502 TYR A O 1 ATOM 3979 C CB . TYR A 1 502 ? 4.598 -8.499 37.596 1.00 16.75 ? 502 TYR A CB 1 ATOM 3980 C CG . TYR A 1 502 ? 4.523 -7.361 38.575 1.00 19.66 ? 502 TYR A CG 1 ATOM 3981 C CD1 . TYR A 1 502 ? 3.336 -6.685 38.781 1.00 19.40 ? 502 TYR A CD1 1 ATOM 3982 C CD2 . TYR A 1 502 ? 5.661 -6.959 39.297 1.00 21.22 ? 502 TYR A CD2 1 ATOM 3983 C CE1 . TYR A 1 502 ? 3.259 -5.626 39.665 1.00 21.21 ? 502 TYR A CE1 1 ATOM 3984 C CE2 . TYR A 1 502 ? 5.601 -5.902 40.193 1.00 23.20 ? 502 TYR A CE2 1 ATOM 3985 C CZ . TYR A 1 502 ? 4.388 -5.244 40.377 1.00 22.34 ? 502 TYR A CZ 1 ATOM 3986 O OH . TYR A 1 502 ? 4.296 -4.204 41.267 1.00 23.48 ? 502 TYR A OH 1 ATOM 3987 N N . SER A 1 503 ? 7.193 -7.434 36.208 1.00 15.46 ? 503 SER A N 1 ATOM 3988 C CA . SER A 1 503 ? 8.354 -6.523 36.117 1.00 16.00 ? 503 SER A CA 1 ATOM 3989 C C . SER A 1 503 ? 8.472 -5.969 34.687 1.00 16.24 ? 503 SER A C 1 ATOM 3990 O O . SER A 1 503 ? 8.739 -4.783 34.473 1.00 16.67 ? 503 SER A O 1 ATOM 3991 C CB . SER A 1 503 ? 9.618 -7.275 36.556 1.00 16.16 ? 503 SER A CB 1 ATOM 3992 O OG . SER A 1 503 ? 9.880 -8.359 35.662 1.00 16.78 ? 503 SER A OG 1 ATOM 3993 N N . MET A 1 504 ? 8.200 -6.815 33.701 1.00 17.36 ? 504 MET A N 1 ATOM 3994 C CA . MET A 1 504 ? 8.201 -6.381 32.314 1.00 17.70 ? 504 MET A CA 1 ATOM 3995 C C . MET A 1 504 ? 7.087 -5.347 32.044 1.00 17.66 ? 504 MET A C 1 ATOM 3996 O O . MET A 1 504 ? 7.322 -4.367 31.356 1.00 17.18 ? 504 MET A O 1 ATOM 3997 C CB . MET A 1 504 ? 8.082 -7.580 31.357 1.00 17.80 ? 504 MET A CB 1 ATOM 3998 C CG . MET A 1 504 ? 8.364 -7.238 29.905 1.00 16.37 ? 504 MET A CG 1 ATOM 3999 S SD . MET A 1 504 ? 8.147 -8.689 28.882 1.00 18.99 ? 504 MET A SD 1 ATOM 4000 C CE . MET A 1 504 ? 8.335 -7.965 27.258 1.00 16.85 ? 504 MET A CE 1 ATOM 4001 N N . ALA A 1 505 ? 5.886 -5.561 32.582 1.00 17.42 ? 505 ALA A N 1 ATOM 4002 C CA . ALA A 1 505 ? 4.806 -4.545 32.434 1.00 17.32 ? 505 ALA A CA 1 ATOM 4003 C C . ALA A 1 505 ? 5.206 -3.227 33.082 1.00 17.27 ? 505 ALA A C 1 ATOM 4004 O O . ALA A 1 505 ? 4.984 -2.158 32.475 1.00 16.81 ? 505 ALA A O 1 ATOM 4005 C CB . ALA A 1 505 ? 3.469 -5.036 33.023 1.00 16.10 ? 505 ALA A CB 1 ATOM 4006 N N . VAL A 1 506 ? 5.816 -3.294 34.279 1.00 17.02 ? 506 VAL A N 1 ATOM 4007 C CA . VAL A 1 506 ? 6.244 -2.064 34.994 1.00 17.55 ? 506 VAL A CA 1 ATOM 4008 C C . VAL A 1 506 ? 7.236 -1.283 34.106 1.00 18.16 ? 506 VAL A C 1 ATOM 4009 O O . VAL A 1 506 ? 7.124 -0.060 33.947 1.00 17.01 ? 506 VAL A O 1 ATOM 4010 C CB . VAL A 1 506 ? 6.817 -2.355 36.394 1.00 18.37 ? 506 VAL A CB 1 ATOM 4011 C CG1 . VAL A 1 506 ? 7.392 -1.092 37.062 1.00 19.03 ? 506 VAL A CG1 1 ATOM 4012 C CG2 . VAL A 1 506 ? 5.739 -3.018 37.316 1.00 17.51 ? 506 VAL A CG2 1 ATOM 4013 N N . ALA A 1 507 ? 8.173 -2.018 33.494 1.00 18.85 ? 507 ALA A N 1 ATOM 4014 C CA . ALA A 1 507 ? 9.259 -1.425 32.675 1.00 18.77 ? 507 ALA A CA 1 ATOM 4015 C C . ALA A 1 507 ? 8.740 -0.890 31.381 1.00 18.12 ? 507 ALA A C 1 ATOM 4016 O O . ALA A 1 507 ? 9.274 0.068 30.842 1.00 18.91 ? 507 ALA A O 1 ATOM 4017 C CB . ALA A 1 507 ? 10.319 -2.469 32.389 1.00 18.35 ? 507 ALA A CB 1 ATOM 4018 N N . THR A 1 508 ? 7.716 -1.536 30.833 1.00 19.50 ? 508 THR A N 1 ATOM 4019 C CA . THR A 1 508 ? 7.134 -1.104 29.569 1.00 19.35 ? 508 THR A CA 1 ATOM 4020 C C . THR A 1 508 ? 6.312 0.185 29.734 1.00 20.32 ? 508 THR A C 1 ATOM 4021 O O . THR A 1 508 ? 6.313 1.057 28.844 1.00 19.27 ? 508 THR A O 1 ATOM 4022 C CB . THR A 1 508 ? 6.348 -2.256 28.901 1.00 20.58 ? 508 THR A CB 1 ATOM 4023 O OG1 . THR A 1 508 ? 7.216 -3.389 28.783 1.00 18.62 ? 508 THR A OG1 1 ATOM 4024 C CG2 . THR A 1 508 ? 5.897 -1.872 27.511 1.00 17.99 ? 508 THR A CG2 1 ATOM 4025 N N . ALA A 1 509 ? 5.632 0.308 30.878 1.00 20.85 ? 509 ALA A N 1 ATOM 4026 C CA . ALA A 1 509 ? 4.940 1.552 31.276 1.00 21.88 ? 509 ALA A CA 1 ATOM 4027 C C . ALA A 1 509 ? 5.915 2.712 31.542 1.00 23.02 ? 509 ALA A C 1 ATOM 4028 O O . ALA A 1 509 ? 5.693 3.835 31.086 1.00 23.48 ? 509 ALA A O 1 ATOM 4029 C CB . ALA A 1 509 ? 4.056 1.306 32.496 1.00 21.01 ? 509 ALA A CB 1 ATOM 4030 N N . GLU A 1 510 ? 7.007 2.436 32.255 1.00 23.99 ? 510 GLU A N 1 ATOM 4031 C CA . GLU A 1 510 ? 8.118 3.394 32.352 1.00 24.61 ? 510 GLU A CA 1 ATOM 4032 C C . GLU A 1 510 ? 8.556 3.922 30.987 1.00 23.96 ? 510 GLU A C 1 ATOM 4033 O O . GLU A 1 510 ? 8.646 5.128 30.800 1.00 23.29 ? 510 GLU A O 1 ATOM 4034 C CB . GLU A 1 510 ? 9.305 2.798 33.140 1.00 25.85 ? 510 GLU A CB 1 ATOM 4035 C CG . GLU A 1 510 ? 10.516 3.731 33.281 1.00 30.46 ? 510 GLU A CG 1 ATOM 4036 C CD . GLU A 1 510 ? 10.323 4.894 34.288 1.00 37.81 ? 510 GLU A CD 1 ATOM 4037 O OE1 . GLU A 1 510 ? 9.284 4.946 35.007 1.00 38.42 ? 510 GLU A OE1 1 ATOM 4038 O OE2 . GLU A 1 510 ? 11.237 5.768 34.354 1.00 39.31 ? 510 GLU A OE2 1 ATOM 4039 N N . ALA A 1 511 ? 8.803 3.016 30.039 1.00 23.96 ? 511 ALA A N 1 ATOM 4040 C CA . ALA A 1 511 ? 9.165 3.351 28.667 1.00 23.36 ? 511 ALA A CA 1 ATOM 4041 C C . ALA A 1 511 ? 8.132 4.243 27.954 1.00 23.63 ? 511 ALA A C 1 ATOM 4042 O O . ALA A 1 511 ? 8.487 5.165 27.192 1.00 23.53 ? 511 ALA A O 1 ATOM 4043 C CB . ALA A 1 511 ? 9.380 2.076 27.880 1.00 22.96 ? 511 ALA A CB 1 ATOM 4044 N N . ALA A 1 512 ? 6.859 3.934 28.169 1.00 22.79 ? 512 ALA A N 1 ATOM 4045 C CA . ALA A 1 512 ? 5.757 4.746 27.658 1.00 23.28 ? 512 ALA A CA 1 ATOM 4046 C C . ALA A 1 512 ? 5.861 6.207 28.143 1.00 23.07 ? 512 ALA A C 1 ATOM 4047 O O . ALA A 1 512 ? 5.521 7.110 27.398 1.00 23.03 ? 512 ALA A O 1 ATOM 4048 C CB . ALA A 1 512 ? 4.406 4.118 28.054 1.00 22.79 ? 512 ALA A CB 1 ATOM 4049 N N . LYS A 1 513 ? 6.366 6.430 29.358 1.00 23.88 ? 513 LYS A N 1 ATOM 4050 C CA . LYS A 1 513 ? 6.626 7.806 29.865 1.00 26.02 ? 513 LYS A CA 1 ATOM 4051 C C . LYS A 1 513 ? 7.442 8.663 28.899 1.00 26.00 ? 513 LYS A C 1 ATOM 4052 O O . LYS A 1 513 ? 7.239 9.870 28.799 1.00 26.25 ? 513 LYS A O 1 ATOM 4053 C CB . LYS A 1 513 ? 7.341 7.789 31.226 1.00 25.96 ? 513 LYS A CB 1 ATOM 4054 C CG . LYS A 1 513 ? 6.474 7.265 32.357 1.00 27.70 ? 513 LYS A CG 1 ATOM 4055 C CD . LYS A 1 513 ? 7.189 7.281 33.679 1.00 29.08 ? 513 LYS A CD 1 ATOM 4056 C CE . LYS A 1 513 ? 6.452 6.375 34.649 1.00 32.80 ? 513 LYS A CE 1 ATOM 4057 N NZ . LYS A 1 513 ? 7.082 6.334 36.011 1.00 33.19 ? 513 LYS A NZ 1 ATOM 4058 N N . THR A 1 514 ? 8.376 8.021 28.209 1.00 26.60 ? 514 THR A N 1 ATOM 4059 C CA . THR A 1 514 ? 9.304 8.703 27.300 1.00 26.14 ? 514 THR A CA 1 ATOM 4060 C C . THR A 1 514 ? 8.770 8.627 25.888 1.00 25.72 ? 514 THR A C 1 ATOM 4061 O O . THR A 1 514 ? 8.817 9.599 25.156 1.00 25.36 ? 514 THR A O 1 ATOM 4062 C CB . THR A 1 514 ? 10.719 8.064 27.362 1.00 26.57 ? 514 THR A CB 1 ATOM 4063 O OG1 . THR A 1 514 ? 11.288 8.295 28.658 1.00 27.19 ? 514 THR A OG1 1 ATOM 4064 C CG2 . THR A 1 514 ? 11.651 8.653 26.293 1.00 25.91 ? 514 THR A CG2 1 ATOM 4065 N N . VAL A 1 515 ? 8.235 7.469 25.517 1.00 25.04 ? 515 VAL A N 1 ATOM 4066 C CA . VAL A 1 515 ? 7.867 7.215 24.135 1.00 25.31 ? 515 VAL A CA 1 ATOM 4067 C C . VAL A 1 515 ? 6.547 7.905 23.766 1.00 25.08 ? 515 VAL A C 1 ATOM 4068 O O . VAL A 1 515 ? 6.373 8.371 22.631 1.00 25.27 ? 515 VAL A O 1 ATOM 4069 C CB . VAL A 1 515 ? 7.810 5.709 23.877 1.00 25.04 ? 515 VAL A CB 1 ATOM 4070 C CG1 . VAL A 1 515 ? 7.280 5.405 22.493 1.00 25.87 ? 515 VAL A CG1 1 ATOM 4071 C CG2 . VAL A 1 515 ? 9.210 5.115 24.059 1.00 25.69 ? 515 VAL A CG2 1 ATOM 4072 N N . PHE A 1 516 ? 5.652 7.987 24.747 1.00 24.86 ? 516 PHE A N 1 ATOM 4073 C CA . PHE A 1 516 ? 4.339 8.623 24.609 1.00 25.12 ? 516 PHE A CA 1 ATOM 4074 C C . PHE A 1 516 ? 4.107 9.639 25.735 1.00 25.93 ? 516 PHE A C 1 ATOM 4075 O O . PHE A 1 516 ? 3.257 9.402 26.616 1.00 26.23 ? 516 PHE A O 1 ATOM 4076 C CB . PHE A 1 516 ? 3.236 7.551 24.692 1.00 24.54 ? 516 PHE A CB 1 ATOM 4077 C CG . PHE A 1 516 ? 3.443 6.401 23.764 1.00 24.11 ? 516 PHE A CG 1 ATOM 4078 C CD1 . PHE A 1 516 ? 3.346 6.572 22.395 1.00 24.74 ? 516 PHE A CD1 1 ATOM 4079 C CD2 . PHE A 1 516 ? 3.739 5.137 24.259 1.00 22.38 ? 516 PHE A CD2 1 ATOM 4080 C CE1 . PHE A 1 516 ? 3.544 5.492 21.529 1.00 24.16 ? 516 PHE A CE1 1 ATOM 4081 C CE2 . PHE A 1 516 ? 3.924 4.069 23.402 1.00 24.28 ? 516 PHE A CE2 1 ATOM 4082 C CZ . PHE A 1 516 ? 3.807 4.245 22.038 1.00 22.25 ? 516 PHE A CZ 1 ATOM 4083 N N . PRO A 1 517 ? 4.849 10.772 25.728 1.00 26.33 ? 517 PRO A N 1 ATOM 4084 C CA . PRO A 1 517 ? 4.831 11.641 26.912 1.00 26.67 ? 517 PRO A CA 1 ATOM 4085 C C . PRO A 1 517 ? 3.437 12.133 27.324 1.00 26.18 ? 517 PRO A C 1 ATOM 4086 O O . PRO A 1 517 ? 2.674 12.624 26.493 1.00 26.23 ? 517 PRO A O 1 ATOM 4087 C CB . PRO A 1 517 ? 5.733 12.822 26.501 1.00 26.68 ? 517 PRO A CB 1 ATOM 4088 C CG . PRO A 1 517 ? 6.654 12.241 25.464 1.00 27.20 ? 517 PRO A CG 1 ATOM 4089 C CD . PRO A 1 517 ? 5.744 11.306 24.680 1.00 26.80 ? 517 PRO A CD 1 ATOM 4090 N N . ASN A 1 518 ? 3.133 11.961 28.607 1.00 26.52 ? 518 ASN A N 1 ATOM 4091 C CA . ASN A 1 518 ? 1.812 12.237 29.199 1.00 26.45 ? 518 ASN A CA 1 ATOM 4092 C C . ASN A 1 518 ? 0.602 11.507 28.615 1.00 25.33 ? 518 ASN A C 1 ATOM 4093 O O . ASN A 1 518 ? -0.522 11.911 28.906 1.00 25.57 ? 518 ASN A O 1 ATOM 4094 C CB . ASN A 1 518 ? 1.513 13.748 29.200 1.00 27.44 ? 518 ASN A CB 1 ATOM 4095 C CG . ASN A 1 518 ? 2.580 14.558 29.898 1.00 30.88 ? 518 ASN A CG 1 ATOM 4096 O OD1 . ASN A 1 518 ? 3.079 14.173 30.979 1.00 34.73 ? 518 ASN A OD1 1 ATOM 4097 N ND2 . ASN A 1 518 ? 2.942 15.702 29.289 1.00 32.68 ? 518 ASN A ND2 1 ATOM 4098 N N . LYS A 1 519 ? 0.820 10.471 27.794 1.00 23.83 ? 519 LYS A N 1 ATOM 4099 C CA . LYS A 1 519 ? -0.276 9.610 27.306 1.00 22.08 ? 519 LYS A CA 1 ATOM 4100 C C . LYS A 1 519 ? -0.273 8.270 28.040 1.00 20.77 ? 519 LYS A C 1 ATOM 4101 O O . LYS A 1 519 ? 0.778 7.792 28.526 1.00 19.65 ? 519 LYS A O 1 ATOM 4102 C CB . LYS A 1 519 ? -0.240 9.372 25.772 1.00 22.66 ? 519 LYS A CB 1 ATOM 4103 C CG . LYS A 1 519 ? -0.157 10.613 24.854 1.00 23.93 ? 519 LYS A CG 1 ATOM 4104 C CD . LYS A 1 519 ? -1.370 11.535 24.976 1.00 28.52 ? 519 LYS A CD 1 ATOM 4105 C CE . LYS A 1 519 ? -1.239 12.768 24.079 1.00 27.24 ? 519 LYS A CE 1 ATOM 4106 N NZ . LYS A 1 519 ? -1.607 13.992 24.856 1.00 31.48 ? 519 LYS A NZ 1 ATOM 4107 N N . ARG A 1 520 ? -1.465 7.679 28.129 1.00 18.30 ? 520 ARG A N 1 ATOM 4108 C CA . ARG A 1 520 ? -1.680 6.357 28.719 1.00 17.14 ? 520 ARG A CA 1 ATOM 4109 C C . ARG A 1 520 ? -1.138 5.259 27.823 1.00 17.57 ? 520 ARG A C 1 ATOM 4110 O O . ARG A 1 520 ? -0.606 4.256 28.320 1.00 16.48 ? 520 ARG A O 1 ATOM 4111 C CB . ARG A 1 520 ? -3.183 6.093 28.897 1.00 17.47 ? 520 ARG A CB 1 ATOM 4112 C CG . ARG A 1 520 ? -3.847 7.071 29.847 1.00 13.91 ? 520 ARG A CG 1 ATOM 4113 C CD . ARG A 1 520 ? -5.360 6.989 29.696 1.00 12.62 ? 520 ARG A CD 1 ATOM 4114 N NE . ARG A 1 520 ? -5.912 8.251 30.161 1.00 10.82 ? 520 ARG A NE 1 ATOM 4115 C CZ . ARG A 1 520 ? -7.195 8.570 30.146 1.00 12.06 ? 520 ARG A CZ 1 ATOM 4116 N NH1 . ARG A 1 520 ? -8.106 7.687 29.734 1.00 8.58 ? 520 ARG A NH1 1 ATOM 4117 N NH2 . ARG A 1 520 ? -7.537 9.783 30.549 1.00 11.71 ? 520 ARG A NH2 1 ATOM 4118 N N . SER A 1 521 ? -1.326 5.441 26.510 1.00 17.19 ? 521 SER A N 1 ATOM 4119 C CA . SER A 1 521 ? -1.006 4.411 25.510 1.00 17.55 ? 521 SER A CA 1 ATOM 4120 C C . SER A 1 521 ? -1.819 3.133 25.820 1.00 17.83 ? 521 SER A C 1 ATOM 4121 O O . SER A 1 521 ? -2.970 3.228 26.255 1.00 17.84 ? 521 SER A O 1 ATOM 4122 C CB . SER A 1 521 ? 0.531 4.177 25.474 1.00 17.68 ? 521 SER A CB 1 ATOM 4123 O OG . SER A 1 521 ? 0.940 3.224 24.491 1.00 17.27 ? 521 SER A OG 1 ATOM 4124 N N . PHE A 1 522 ? -1.223 1.959 25.619 1.00 16.90 ? 522 PHE A N 1 ATOM 4125 C CA . PHE A 1 522 ? -1.897 0.677 25.825 1.00 17.35 ? 522 PHE A CA 1 ATOM 4126 C C . PHE A 1 522 ? -0.816 -0.385 25.922 1.00 17.23 ? 522 PHE A C 1 ATOM 4127 O O . PHE A 1 522 ? 0.082 -0.410 25.089 1.00 17.13 ? 522 PHE A O 1 ATOM 4128 C CB . PHE A 1 522 ? -2.823 0.361 24.640 1.00 15.86 ? 522 PHE A CB 1 ATOM 4129 C CG . PHE A 1 522 ? -3.383 -1.046 24.638 1.00 17.01 ? 522 PHE A CG 1 ATOM 4130 C CD1 . PHE A 1 522 ? -4.437 -1.395 25.482 1.00 16.95 ? 522 PHE A CD1 1 ATOM 4131 C CD2 . PHE A 1 522 ? -2.890 -2.009 23.751 1.00 15.01 ? 522 PHE A CD2 1 ATOM 4132 C CE1 . PHE A 1 522 ? -4.972 -2.698 25.471 1.00 18.24 ? 522 PHE A CE1 1 ATOM 4133 C CE2 . PHE A 1 522 ? -3.418 -3.308 23.741 1.00 17.13 ? 522 PHE A CE2 1 ATOM 4134 C CZ . PHE A 1 522 ? -4.471 -3.641 24.600 1.00 17.05 ? 522 PHE A CZ 1 ATOM 4135 N N . ILE A 1 523 ? -0.896 -1.233 26.951 1.00 17.38 ? 523 ILE A N 1 ATOM 4136 C CA . ILE A 1 523 ? 0.003 -2.380 27.101 1.00 16.43 ? 523 ILE A CA 1 ATOM 4137 C C . ILE A 1 523 ? -0.849 -3.597 27.326 1.00 16.30 ? 523 ILE A C 1 ATOM 4138 O O . ILE A 1 523 ? -1.660 -3.586 28.219 1.00 16.93 ? 523 ILE A O 1 ATOM 4139 C CB . ILE A 1 523 ? 0.921 -2.233 28.299 1.00 16.01 ? 523 ILE A CB 1 ATOM 4140 C CG1 . ILE A 1 523 ? 1.883 -1.044 28.102 1.00 16.64 ? 523 ILE A CG1 1 ATOM 4141 C CG2 . ILE A 1 523 ? 1.700 -3.535 28.509 1.00 15.30 ? 523 ILE A CG2 1 ATOM 4142 C CD1 . ILE A 1 523 ? 2.671 -0.712 29.337 1.00 15.40 ? 523 ILE A CD1 1 ATOM 4143 N N . LEU A 1 524 ? -0.678 -4.617 26.485 1.00 16.28 ? 524 LEU A N 1 ATOM 4144 C CA . LEU A 1 524 ? -1.296 -5.928 26.630 1.00 15.77 ? 524 LEU A CA 1 ATOM 4145 C C . LEU A 1 524 ? -0.236 -6.946 27.030 1.00 16.37 ? 524 LEU A C 1 ATOM 4146 O O . LEU A 1 524 ? 0.771 -7.095 26.323 1.00 16.88 ? 524 LEU A O 1 ATOM 4147 C CB . LEU A 1 524 ? -1.936 -6.345 25.315 1.00 14.86 ? 524 LEU A CB 1 ATOM 4148 C CG . LEU A 1 524 ? -2.729 -7.655 25.295 1.00 16.49 ? 524 LEU A CG 1 ATOM 4149 C CD1 . LEU A 1 524 ? -4.053 -7.520 26.098 1.00 13.08 ? 524 LEU A CD1 1 ATOM 4150 C CD2 . LEU A 1 524 ? -2.996 -8.049 23.858 1.00 14.94 ? 524 LEU A CD2 1 ATOM 4151 N N . THR A 1 525 ? -0.450 -7.628 28.160 1.00 16.43 ? 525 THR A N 1 ATOM 4152 C CA . THR A 1 525 ? 0.507 -8.623 28.717 1.00 16.57 ? 525 THR A CA 1 ATOM 4153 C C . THR A 1 525 ? -0.077 -10.028 28.801 1.00 17.33 ? 525 THR A C 1 ATOM 4154 O O . THR A 1 525 ? -1.296 -10.225 29.045 1.00 17.19 ? 525 THR A O 1 ATOM 4155 C CB . THR A 1 525 ? 1.103 -8.192 30.083 1.00 17.02 ? 525 THR A CB 1 ATOM 4156 O OG1 . THR A 1 525 ? 2.238 -9.018 30.410 1.00 16.62 ? 525 THR A OG1 1 ATOM 4157 C CG2 . THR A 1 525 ? 0.043 -8.253 31.204 1.00 16.35 ? 525 THR A CG2 1 ATOM 4158 N N . ARG A 1 526 ? 0.775 -11.015 28.531 1.00 17.22 ? 526 ARG A N 1 ATOM 4159 C CA . ARG A 1 526 ? 0.361 -12.405 28.695 1.00 16.53 ? 526 ARG A CA 1 ATOM 4160 C C . ARG A 1 526 ? 0.473 -12.800 30.162 1.00 16.42 ? 526 ARG A C 1 ATOM 4161 O O . ARG A 1 526 ? -0.528 -13.181 30.801 1.00 16.36 ? 526 ARG A O 1 ATOM 4162 C CB . ARG A 1 526 ? 1.181 -13.373 27.813 1.00 15.76 ? 526 ARG A CB 1 ATOM 4163 C CG . ARG A 1 526 ? 0.487 -14.709 27.735 1.00 15.70 ? 526 ARG A CG 1 ATOM 4164 C CD . ARG A 1 526 ? 0.974 -15.565 26.663 1.00 15.91 ? 526 ARG A CD 1 ATOM 4165 N NE . ARG A 1 526 ? 2.226 -16.187 27.055 1.00 20.41 ? 526 ARG A NE 1 ATOM 4166 C CZ . ARG A 1 526 ? 2.852 -17.100 26.332 1.00 21.56 ? 526 ARG A CZ 1 ATOM 4167 N NH1 . ARG A 1 526 ? 2.344 -17.486 25.166 1.00 23.45 ? 526 ARG A NH1 1 ATOM 4168 N NH2 . ARG A 1 526 ? 3.978 -17.606 26.770 1.00 20.71 ? 526 ARG A NH2 1 ATOM 4169 N N . SER A 1 527 ? 1.694 -12.708 30.685 1.00 14.99 ? 527 SER A N 1 ATOM 4170 C CA . SER A 1 527 ? 1.971 -13.101 32.065 1.00 16.01 ? 527 SER A CA 1 ATOM 4171 C C . SER A 1 527 ? 1.640 -11.966 33.045 1.00 15.73 ? 527 SER A C 1 ATOM 4172 O O . SER A 1 527 ? 1.931 -10.789 32.765 1.00 17.67 ? 527 SER A O 1 ATOM 4173 C CB . SER A 1 527 ? 3.436 -13.551 32.182 1.00 16.49 ? 527 SER A CB 1 ATOM 4174 O OG . SER A 1 527 ? 3.771 -13.942 33.504 1.00 19.11 ? 527 SER A OG 1 ATOM 4175 N N . THR A 1 528 ? 1.029 -12.299 34.181 1.00 14.56 ? 528 THR A N 1 ATOM 4176 C CA . THR A 1 528 ? 0.615 -11.280 35.157 1.00 13.75 ? 528 THR A CA 1 ATOM 4177 C C . THR A 1 528 ? 0.901 -11.786 36.545 1.00 13.06 ? 528 THR A C 1 ATOM 4178 O O . THR A 1 528 ? 1.074 -12.970 36.767 1.00 13.50 ? 528 THR A O 1 ATOM 4179 C CB . THR A 1 528 ? -0.926 -11.006 35.130 1.00 14.40 ? 528 THR A CB 1 ATOM 4180 O OG1 . THR A 1 528 ? -1.585 -12.199 35.517 1.00 14.04 ? 528 THR A OG1 1 ATOM 4181 C CG2 . THR A 1 528 ? -1.405 -10.567 33.762 1.00 11.67 ? 528 THR A CG2 1 ATOM 4182 N N . PHE A 1 529 ? 0.882 -10.872 37.495 1.00 13.15 ? 529 PHE A N 1 ATOM 4183 C CA . PHE A 1 529 ? 0.981 -11.200 38.888 1.00 14.27 ? 529 PHE A CA 1 ATOM 4184 C C . PHE A 1 529 ? -0.021 -10.261 39.522 1.00 14.18 ? 529 PHE A C 1 ATOM 4185 O O . PHE A 1 529 ? -0.581 -9.419 38.826 1.00 16.64 ? 529 PHE A O 1 ATOM 4186 C CB . PHE A 1 529 ? 2.395 -10.915 39.423 1.00 14.02 ? 529 PHE A CB 1 ATOM 4187 C CG . PHE A 1 529 ? 2.604 -11.359 40.865 1.00 15.34 ? 529 PHE A CG 1 ATOM 4188 C CD1 . PHE A 1 529 ? 2.677 -12.701 41.186 1.00 18.07 ? 529 PHE A CD1 1 ATOM 4189 C CD2 . PHE A 1 529 ? 2.742 -10.434 41.868 1.00 15.88 ? 529 PHE A CD2 1 ATOM 4190 C CE1 . PHE A 1 529 ? 2.864 -13.123 42.510 1.00 18.28 ? 529 PHE A CE1 1 ATOM 4191 C CE2 . PHE A 1 529 ? 2.937 -10.828 43.189 1.00 16.69 ? 529 PHE A CE2 1 ATOM 4192 C CZ . PHE A 1 529 ? 2.995 -12.179 43.509 1.00 16.63 ? 529 PHE A CZ 1 ATOM 4193 N N . ALA A 1 530 ? -0.263 -10.404 40.812 1.00 14.01 ? 530 ALA A N 1 ATOM 4194 C CA . ALA A 1 530 ? -1.145 -9.493 41.543 1.00 15.26 ? 530 ALA A CA 1 ATOM 4195 C C . ALA A 1 530 ? -0.661 -8.066 41.378 1.00 16.52 ? 530 ALA A C 1 ATOM 4196 O O . ALA A 1 530 ? 0.493 -7.712 41.716 1.00 17.34 ? 530 ALA A O 1 ATOM 4197 C CB . ALA A 1 530 ? -1.219 -9.864 42.991 1.00 14.78 ? 530 ALA A CB 1 ATOM 4198 N N . GLY A 1 531 ? -1.525 -7.262 40.769 1.00 16.57 ? 531 GLY A N 1 ATOM 4199 C CA . GLY A 1 531 ? -1.225 -5.871 40.563 1.00 15.06 ? 531 GLY A CA 1 ATOM 4200 C C . GLY A 1 531 ? -0.886 -5.435 39.169 1.00 14.82 ? 531 GLY A C 1 ATOM 4201 O O . GLY A 1 531 ? -0.735 -4.249 38.950 1.00 15.97 ? 531 GLY A O 1 ATOM 4202 N N . SER A 1 532 ? -0.749 -6.382 38.233 1.00 14.48 ? 532 SER A N 1 ATOM 4203 C CA . SER A 1 532 ? -0.397 -6.093 36.836 1.00 13.83 ? 532 SER A CA 1 ATOM 4204 C C . SER A 1 532 ? -1.374 -5.178 36.135 1.00 14.10 ? 532 SER A C 1 ATOM 4205 O O . SER A 1 532 ? -1.020 -4.471 35.171 1.00 12.77 ? 532 SER A O 1 ATOM 4206 C CB . SER A 1 532 ? -0.315 -7.388 36.034 1.00 12.55 ? 532 SER A CB 1 ATOM 4207 O OG . SER A 1 532 ? 0.815 -8.139 36.395 1.00 15.95 ? 532 SER A OG 1 ATOM 4208 N N . GLY A 1 533 ? -2.622 -5.226 36.596 1.00 13.65 ? 533 GLY A N 1 ATOM 4209 C CA . GLY A 1 533 ? -3.646 -4.315 36.076 1.00 14.51 ? 533 GLY A CA 1 ATOM 4210 C C . GLY A 1 533 ? -3.373 -2.839 36.220 1.00 14.29 ? 533 GLY A C 1 ATOM 4211 O O . GLY A 1 533 ? -3.869 -2.021 35.440 1.00 14.16 ? 533 GLY A O 1 ATOM 4212 N N . LYS A 1 534 ? -2.570 -2.472 37.211 1.00 15.77 ? 534 LYS A N 1 ATOM 4213 C CA . LYS A 1 534 ? -2.098 -1.098 37.302 1.00 16.62 ? 534 LYS A CA 1 ATOM 4214 C C . LYS A 1 534 ? -1.439 -0.667 35.981 1.00 16.77 ? 534 LYS A C 1 ATOM 4215 O O . LYS A 1 534 ? -1.531 0.491 35.578 1.00 17.26 ? 534 LYS A O 1 ATOM 4216 C CB . LYS A 1 534 ? -1.145 -0.969 38.475 1.00 17.46 ? 534 LYS A CB 1 ATOM 4217 C CG . LYS A 1 534 ? -0.937 0.418 38.972 1.00 19.96 ? 534 LYS A CG 1 ATOM 4218 C CD . LYS A 1 534 ? -0.047 0.426 40.217 1.00 22.24 ? 534 LYS A CD 1 ATOM 4219 C CE . LYS A 1 534 ? 0.441 1.853 40.451 1.00 26.50 ? 534 LYS A CE 1 ATOM 4220 N NZ . LYS A 1 534 ? 0.987 2.026 41.810 1.00 29.14 ? 534 LYS A NZ 1 ATOM 4221 N N . PHE A 1 535 ? -0.853 -1.625 35.266 1.00 17.31 ? 535 PHE A N 1 ATOM 4222 C CA . PHE A 1 535 ? 0.022 -1.334 34.119 1.00 16.81 ? 535 PHE A CA 1 ATOM 4223 C C . PHE A 1 535 ? -0.477 -1.834 32.796 1.00 16.29 ? 535 PHE A C 1 ATOM 4224 O O . PHE A 1 535 ? -0.196 -1.233 31.757 1.00 16.90 ? 535 PHE A O 1 ATOM 4225 C CB . PHE A 1 535 ? 1.440 -1.887 34.374 1.00 17.51 ? 535 PHE A CB 1 ATOM 4226 C CG . PHE A 1 535 ? 1.991 -1.499 35.707 1.00 19.27 ? 535 PHE A CG 1 ATOM 4227 C CD1 . PHE A 1 535 ? 2.574 -0.253 35.894 1.00 18.34 ? 535 PHE A CD1 1 ATOM 4228 C CD2 . PHE A 1 535 ? 1.912 -2.370 36.784 1.00 20.18 ? 535 PHE A CD2 1 ATOM 4229 C CE1 . PHE A 1 535 ? 3.057 0.121 37.135 1.00 18.82 ? 535 PHE A CE1 1 ATOM 4230 C CE2 . PHE A 1 535 ? 2.397 -1.986 38.038 1.00 19.73 ? 535 PHE A CE2 1 ATOM 4231 C CZ . PHE A 1 535 ? 2.974 -0.746 38.200 1.00 17.93 ? 535 PHE A CZ 1 ATOM 4232 N N . ALA A 1 536 ? -1.279 -2.893 32.806 1.00 15.91 ? 536 ALA A N 1 ATOM 4233 C CA . ALA A 1 536 ? -1.584 -3.563 31.564 1.00 15.17 ? 536 ALA A CA 1 ATOM 4234 C C . ALA A 1 536 ? -2.948 -4.239 31.524 1.00 15.33 ? 536 ALA A C 1 ATOM 4235 O O . ALA A 1 536 ? -3.486 -4.599 32.548 1.00 14.84 ? 536 ALA A O 1 ATOM 4236 C CB . ALA A 1 536 ? -0.509 -4.605 31.313 1.00 15.31 ? 536 ALA A CB 1 ATOM 4237 N N . ALA A 1 537 ? -3.436 -4.435 30.308 1.00 14.14 ? 537 ALA A N 1 ATOM 4238 C CA . ALA A 1 537 ? -4.520 -5.342 29.979 1.00 14.52 ? 537 ALA A CA 1 ATOM 4239 C C . ALA A 1 537 ? -3.991 -6.757 29.795 1.00 14.15 ? 537 ALA A C 1 ATOM 4240 O O . ALA A 1 537 ? -2.766 -6.987 29.693 1.00 14.53 ? 537 ALA A O 1 ATOM 4241 C CB . ALA A 1 537 ? -5.217 -4.870 28.694 1.00 13.61 ? 537 ALA A CB 1 ATOM 4242 N N . HIS A 1 538 ? -4.908 -7.706 29.714 1.00 14.04 ? 538 HIS A N 1 ATOM 4243 C CA . HIS A 1 538 ? -4.533 -9.107 29.578 1.00 14.93 ? 538 HIS A CA 1 ATOM 4244 C C . HIS A 1 538 ? -5.404 -9.762 28.535 1.00 15.36 ? 538 HIS A C 1 ATOM 4245 O O . HIS A 1 538 ? -6.584 -9.421 28.390 1.00 15.39 ? 538 HIS A O 1 ATOM 4246 C CB . HIS A 1 538 ? -4.648 -9.801 30.960 1.00 14.91 ? 538 HIS A CB 1 ATOM 4247 C CG . HIS A 1 538 ? -4.408 -11.278 30.936 1.00 15.99 ? 538 HIS A CG 1 ATOM 4248 N ND1 . HIS A 1 538 ? -3.176 -11.836 30.632 1.00 13.99 ? 538 HIS A ND1 1 ATOM 4249 C CD2 . HIS A 1 538 ? -5.240 -12.314 31.209 1.00 13.11 ? 538 HIS A CD2 1 ATOM 4250 C CE1 . HIS A 1 538 ? -3.268 -13.148 30.695 1.00 13.74 ? 538 HIS A CE1 1 ATOM 4251 N NE2 . HIS A 1 538 ? -4.505 -13.467 31.049 1.00 18.08 ? 538 HIS A NE2 1 ATOM 4252 N N . TRP A 1 539 ? -4.849 -10.710 27.784 1.00 15.20 ? 539 TRP A N 1 ATOM 4253 C CA . TRP A 1 539 ? -5.731 -11.595 27.025 1.00 15.34 ? 539 TRP A CA 1 ATOM 4254 C C . TRP A 1 539 ? -5.504 -13.041 27.476 1.00 16.14 ? 539 TRP A C 1 ATOM 4255 O O . TRP A 1 539 ? -4.408 -13.377 27.950 1.00 16.04 ? 539 TRP A O 1 ATOM 4256 C CB . TRP A 1 539 ? -5.582 -11.404 25.507 1.00 14.87 ? 539 TRP A CB 1 ATOM 4257 C CG . TRP A 1 539 ? -4.563 -12.306 24.853 1.00 14.73 ? 539 TRP A CG 1 ATOM 4258 C CD1 . TRP A 1 539 ? -4.821 -13.355 24.027 1.00 13.56 ? 539 TRP A CD1 1 ATOM 4259 C CD2 . TRP A 1 539 ? -3.128 -12.224 24.971 1.00 14.23 ? 539 TRP A CD2 1 ATOM 4260 N NE1 . TRP A 1 539 ? -3.625 -13.935 23.612 1.00 13.82 ? 539 TRP A NE1 1 ATOM 4261 C CE2 . TRP A 1 539 ? -2.580 -13.255 24.178 1.00 14.45 ? 539 TRP A CE2 1 ATOM 4262 C CE3 . TRP A 1 539 ? -2.261 -11.382 25.667 1.00 14.38 ? 539 TRP A CE3 1 ATOM 4263 C CZ2 . TRP A 1 539 ? -1.202 -13.475 24.074 1.00 15.84 ? 539 TRP A CZ2 1 ATOM 4264 C CZ3 . TRP A 1 539 ? -0.888 -11.583 25.544 1.00 15.17 ? 539 TRP A CZ3 1 ATOM 4265 C CH2 . TRP A 1 539 ? -0.373 -12.634 24.773 1.00 14.44 ? 539 TRP A CH2 1 ATOM 4266 N N . LEU A 1 540 ? -6.516 -13.891 27.296 1.00 15.56 ? 540 LEU A N 1 ATOM 4267 C CA . LEU A 1 540 ? -6.528 -15.208 27.947 1.00 16.30 ? 540 LEU A CA 1 ATOM 4268 C C . LEU A 1 540 ? -5.665 -16.264 27.243 1.00 16.49 ? 540 LEU A C 1 ATOM 4269 O O . LEU A 1 540 ? -5.677 -17.433 27.615 1.00 16.86 ? 540 LEU A O 1 ATOM 4270 C CB . LEU A 1 540 ? -7.965 -15.705 28.145 1.00 15.53 ? 540 LEU A CB 1 ATOM 4271 C CG . LEU A 1 540 ? -8.754 -14.709 28.978 1.00 16.09 ? 540 LEU A CG 1 ATOM 4272 C CD1 . LEU A 1 540 ? -10.250 -14.949 28.886 1.00 14.24 ? 540 LEU A CD1 1 ATOM 4273 C CD2 . LEU A 1 540 ? -8.245 -14.776 30.421 1.00 15.45 ? 540 LEU A CD2 1 ATOM 4274 N N . GLY A 1 541 ? -4.926 -15.851 26.225 1.00 16.59 ? 541 GLY A N 1 ATOM 4275 C CA . GLY A 1 541 ? -3.940 -16.725 25.597 1.00 17.69 ? 541 GLY A CA 1 ATOM 4276 C C . GLY A 1 541 ? -4.457 -17.525 24.438 1.00 17.64 ? 541 GLY A C 1 ATOM 4277 O O . GLY A 1 541 ? -5.452 -17.151 23.788 1.00 18.21 ? 541 GLY A O 1 ATOM 4278 N N . ASP A 1 542 ? -3.790 -18.651 24.197 1.00 17.87 ? 542 ASP A N 1 ATOM 4279 C CA . ASP A 1 542 ? -3.988 -19.454 22.994 1.00 17.21 ? 542 ASP A CA 1 ATOM 4280 C C . ASP A 1 542 ? -5.129 -20.416 23.133 1.00 17.17 ? 542 ASP A C 1 ATOM 4281 O O . ASP A 1 542 ? -4.918 -21.624 23.324 1.00 16.18 ? 542 ASP A O 1 ATOM 4282 C CB . ASP A 1 542 ? -2.702 -20.213 22.653 1.00 18.07 ? 542 ASP A CB 1 ATOM 4283 C CG . ASP A 1 542 ? -1.641 -19.310 22.108 1.00 18.66 ? 542 ASP A CG 1 ATOM 4284 O OD1 . ASP A 1 542 ? -1.979 -18.133 21.870 1.00 22.40 ? 542 ASP A OD1 1 ATOM 4285 O OD2 . ASP A 1 542 ? -0.472 -19.750 21.940 1.00 21.36 ? 542 ASP A OD2 1 ATOM 4286 N N . ASN A 1 543 ? -6.350 -19.884 23.030 1.00 16.98 ? 543 ASN A N 1 ATOM 4287 C CA . ASN A 1 543 ? -7.522 -20.724 22.992 1.00 16.52 ? 543 ASN A CA 1 ATOM 4288 C C . ASN A 1 543 ? -7.673 -21.425 21.629 1.00 17.57 ? 543 ASN A C 1 ATOM 4289 O O . ASN A 1 543 ? -6.782 -21.402 20.783 1.00 17.91 ? 543 ASN A O 1 ATOM 4290 C CB . ASN A 1 543 ? -8.796 -19.931 23.390 1.00 15.76 ? 543 ASN A CB 1 ATOM 4291 C CG . ASN A 1 543 ? -9.148 -18.843 22.395 1.00 16.24 ? 543 ASN A CG 1 ATOM 4292 O OD1 . ASN A 1 543 ? -8.382 -18.575 21.464 1.00 18.36 ? 543 ASN A OD1 1 ATOM 4293 N ND2 . ASN A 1 543 ? -10.321 -18.215 22.569 1.00 15.00 ? 543 ASN A ND2 1 ATOM 4294 N N . THR A 1 544 ? -8.829 -22.033 21.428 1.00 18.61 ? 544 THR A N 1 ATOM 4295 C CA . THR A 1 544 ? -9.081 -22.874 20.297 1.00 20.03 ? 544 THR A CA 1 ATOM 4296 C C . THR A 1 544 ? -10.473 -22.523 19.813 1.00 20.01 ? 544 THR A C 1 ATOM 4297 O O . THR A 1 544 ? -11.322 -22.075 20.596 1.00 19.59 ? 544 THR A O 1 ATOM 4298 C CB . THR A 1 544 ? -8.924 -24.368 20.690 1.00 20.65 ? 544 THR A CB 1 ATOM 4299 O OG1 . THR A 1 544 ? -7.605 -24.547 21.217 1.00 24.08 ? 544 THR A OG1 1 ATOM 4300 C CG2 . THR A 1 544 ? -9.065 -25.309 19.473 1.00 21.58 ? 544 THR A CG2 1 ATOM 4301 N N . ALA A 1 545 ? -10.685 -22.664 18.507 1.00 19.59 ? 545 ALA A N 1 ATOM 4302 C CA . ALA A 1 545 ? -11.970 -22.365 17.917 1.00 19.53 ? 545 ALA A CA 1 ATOM 4303 C C . ALA A 1 545 ? -12.949 -23.503 18.191 1.00 19.31 ? 545 ALA A C 1 ATOM 4304 O O . ALA A 1 545 ? -13.272 -24.280 17.299 1.00 18.75 ? 545 ALA A O 1 ATOM 4305 C CB . ALA A 1 545 ? -11.795 -22.118 16.431 1.00 19.83 ? 545 ALA A CB 1 ATOM 4306 N N . THR A 1 546 ? -13.360 -23.642 19.457 1.00 18.80 ? 546 THR A N 1 ATOM 4307 C CA . THR A 1 546 ? -14.384 -24.619 19.839 1.00 18.22 ? 546 THR A CA 1 ATOM 4308 C C . THR A 1 546 ? -15.470 -23.964 20.693 1.00 17.22 ? 546 THR A C 1 ATOM 4309 O O . THR A 1 546 ? -15.266 -22.911 21.279 1.00 14.16 ? 546 THR A O 1 ATOM 4310 C CB . THR A 1 546 ? -13.836 -25.840 20.649 1.00 18.90 ? 546 THR A CB 1 ATOM 4311 O OG1 . THR A 1 546 ? -13.530 -25.441 21.994 1.00 21.40 ? 546 THR A OG1 1 ATOM 4312 C CG2 . THR A 1 546 ? -12.576 -26.470 20.000 1.00 19.89 ? 546 THR A CG2 1 ATOM 4313 N N . TRP A 1 547 ? -16.617 -24.627 20.773 1.00 17.23 ? 547 TRP A N 1 ATOM 4314 C CA . TRP A 1 547 ? -17.714 -24.188 21.630 1.00 17.52 ? 547 TRP A CA 1 ATOM 4315 C C . TRP A 1 547 ? -17.358 -24.206 23.136 1.00 18.07 ? 547 TRP A C 1 ATOM 4316 O O . TRP A 1 547 ? -17.757 -23.309 23.877 1.00 16.55 ? 547 TRP A O 1 ATOM 4317 C CB . TRP A 1 547 ? -18.966 -25.005 21.312 1.00 17.99 ? 547 TRP A CB 1 ATOM 4318 C CG . TRP A 1 547 ? -19.517 -24.637 19.981 1.00 18.24 ? 547 TRP A CG 1 ATOM 4319 C CD1 . TRP A 1 547 ? -19.224 -25.224 18.776 1.00 19.47 ? 547 TRP A CD1 1 ATOM 4320 C CD2 . TRP A 1 547 ? -20.405 -23.562 19.699 1.00 18.16 ? 547 TRP A CD2 1 ATOM 4321 N NE1 . TRP A 1 547 ? -19.912 -24.591 17.769 1.00 20.39 ? 547 TRP A NE1 1 ATOM 4322 C CE2 . TRP A 1 547 ? -20.639 -23.564 18.309 1.00 19.62 ? 547 TRP A CE2 1 ATOM 4323 C CE3 . TRP A 1 547 ? -21.039 -22.597 20.486 1.00 18.36 ? 547 TRP A CE3 1 ATOM 4324 C CZ2 . TRP A 1 547 ? -21.501 -22.654 17.696 1.00 19.31 ? 547 TRP A CZ2 1 ATOM 4325 C CZ3 . TRP A 1 547 ? -21.878 -21.675 19.865 1.00 18.32 ? 547 TRP A CZ3 1 ATOM 4326 C CH2 . TRP A 1 547 ? -22.102 -21.716 18.491 1.00 18.15 ? 547 TRP A CH2 1 ATOM 4327 N N . ASP A 1 548 ? -16.584 -25.204 23.563 1.00 19.02 ? 548 ASP A N 1 ATOM 4328 C CA . ASP A 1 548 ? -16.025 -25.259 24.928 1.00 19.45 ? 548 ASP A CA 1 ATOM 4329 C C . ASP A 1 548 ? -15.257 -23.987 25.265 1.00 19.22 ? 548 ASP A C 1 ATOM 4330 O O . ASP A 1 548 ? -15.567 -23.350 26.270 1.00 19.58 ? 548 ASP A O 1 ATOM 4331 C CB . ASP A 1 548 ? -15.115 -26.471 25.110 1.00 20.28 ? 548 ASP A CB 1 ATOM 4332 C CG . ASP A 1 548 ? -15.872 -27.738 25.444 1.00 23.15 ? 548 ASP A CG 1 ATOM 4333 O OD1 . ASP A 1 548 ? -16.937 -27.673 26.091 1.00 25.44 ? 548 ASP A OD1 1 ATOM 4334 O OD2 . ASP A 1 548 ? -15.364 -28.816 25.081 1.00 26.86 ? 548 ASP A OD2 1 ATOM 4335 N N . ASP A 1 549 ? -14.277 -23.613 24.431 1.00 18.72 ? 549 ASP A N 1 ATOM 4336 C CA . ASP A 1 549 ? -13.532 -22.348 24.617 1.00 18.94 ? 549 ASP A CA 1 ATOM 4337 C C . ASP A 1 549 ? -14.396 -21.060 24.658 1.00 18.15 ? 549 ASP A C 1 ATOM 4338 O O . ASP A 1 549 ? -14.102 -20.124 25.397 1.00 18.43 ? 549 ASP A O 1 ATOM 4339 C CB . ASP A 1 549 ? -12.413 -22.180 23.577 1.00 18.87 ? 549 ASP A CB 1 ATOM 4340 C CG . ASP A 1 549 ? -11.308 -23.229 23.701 1.00 21.35 ? 549 ASP A CG 1 ATOM 4341 O OD1 . ASP A 1 549 ? -10.186 -22.878 24.102 1.00 23.90 ? 549 ASP A OD1 1 ATOM 4342 O OD2 . ASP A 1 549 ? -11.538 -24.407 23.351 1.00 25.73 ? 549 ASP A OD2 1 ATOM 4343 N N . LEU A 1 550 ? -15.439 -20.989 23.845 1.00 17.75 ? 550 LEU A N 1 ATOM 4344 C CA . LEU A 1 550 ? -16.364 -19.859 23.920 1.00 16.74 ? 550 LEU A CA 1 ATOM 4345 C C . LEU A 1 550 ? -16.977 -19.781 25.321 1.00 16.19 ? 550 LEU A C 1 ATOM 4346 O O . LEU A 1 550 ? -16.934 -18.731 25.980 1.00 15.26 ? 550 LEU A O 1 ATOM 4347 C CB . LEU A 1 550 ? -17.423 -19.964 22.802 1.00 17.16 ? 550 LEU A CB 1 ATOM 4348 C CG . LEU A 1 550 ? -18.676 -19.077 22.882 1.00 17.33 ? 550 LEU A CG 1 ATOM 4349 C CD1 . LEU A 1 550 ? -18.348 -17.630 22.733 1.00 16.47 ? 550 LEU A CD1 1 ATOM 4350 C CD2 . LEU A 1 550 ? -19.659 -19.486 21.831 1.00 17.39 ? 550 LEU A CD2 1 ATOM 4351 N N . ARG A 1 551 ? -17.533 -20.899 25.790 1.00 16.87 ? 551 ARG A N 1 ATOM 4352 C CA . ARG A 1 551 ? -18.065 -20.999 27.158 1.00 16.38 ? 551 ARG A CA 1 ATOM 4353 C C . ARG A 1 551 ? -17.041 -20.692 28.281 1.00 16.44 ? 551 ARG A C 1 ATOM 4354 O O . ARG A 1 551 ? -17.321 -19.915 29.211 1.00 16.80 ? 551 ARG A O 1 ATOM 4355 C CB . ARG A 1 551 ? -18.710 -22.370 27.358 1.00 17.08 ? 551 ARG A CB 1 ATOM 4356 C CG . ARG A 1 551 ? -20.011 -22.560 26.546 1.00 18.18 ? 551 ARG A CG 1 ATOM 4357 C CD . ARG A 1 551 ? -20.717 -23.837 26.938 1.00 20.65 ? 551 ARG A CD 1 ATOM 4358 N NE . ARG A 1 551 ? -20.053 -25.049 26.475 1.00 19.99 ? 551 ARG A NE 1 ATOM 4359 C CZ . ARG A 1 551 ? -20.204 -25.598 25.265 1.00 22.75 ? 551 ARG A CZ 1 ATOM 4360 N NH1 . ARG A 1 551 ? -20.974 -25.018 24.350 1.00 26.01 ? 551 ARG A NH1 1 ATOM 4361 N NH2 . ARG A 1 551 ? -19.564 -26.721 24.960 1.00 20.18 ? 551 ARG A NH2 1 ATOM 4362 N N . TRP A 1 552 ? -15.851 -21.261 28.190 1.00 16.56 ? 552 TRP A N 1 ATOM 4363 C CA . TRP A 1 552 ? -14.806 -21.005 29.215 1.00 16.64 ? 552 TRP A CA 1 ATOM 4364 C C . TRP A 1 552 ? -14.315 -19.568 29.278 1.00 16.76 ? 552 TRP A C 1 ATOM 4365 O O . TRP A 1 552 ? -13.778 -19.155 30.307 1.00 17.45 ? 552 TRP A O 1 ATOM 4366 C CB . TRP A 1 552 ? -13.633 -21.969 29.055 1.00 17.25 ? 552 TRP A CB 1 ATOM 4367 C CG . TRP A 1 552 ? -14.049 -23.421 29.068 1.00 17.52 ? 552 TRP A CG 1 ATOM 4368 C CD1 . TRP A 1 552 ? -15.202 -23.954 29.617 1.00 16.92 ? 552 TRP A CD1 1 ATOM 4369 C CD2 . TRP A 1 552 ? -13.319 -24.526 28.518 1.00 17.08 ? 552 TRP A CD2 1 ATOM 4370 N NE1 . TRP A 1 552 ? -15.228 -25.308 29.417 1.00 17.47 ? 552 TRP A NE1 1 ATOM 4371 C CE2 . TRP A 1 552 ? -14.078 -25.683 28.755 1.00 18.62 ? 552 TRP A CE2 1 ATOM 4372 C CE3 . TRP A 1 552 ? -12.094 -24.643 27.847 1.00 19.09 ? 552 TRP A CE3 1 ATOM 4373 C CZ2 . TRP A 1 552 ? -13.648 -26.950 28.341 1.00 20.07 ? 552 TRP A CZ2 1 ATOM 4374 C CZ3 . TRP A 1 552 ? -11.667 -25.897 27.440 1.00 17.77 ? 552 TRP A CZ3 1 ATOM 4375 C CH2 . TRP A 1 552 ? -12.437 -27.029 27.696 1.00 18.68 ? 552 TRP A CH2 1 ATOM 4376 N N . SER A 1 553 ? -14.515 -18.793 28.211 1.00 16.36 ? 553 SER A N 1 ATOM 4377 C CA . SER A 1 553 ? -14.090 -17.377 28.192 1.00 17.23 ? 553 SER A CA 1 ATOM 4378 C C . SER A 1 553 ? -14.724 -16.555 29.300 1.00 16.93 ? 553 SER A C 1 ATOM 4379 O O . SER A 1 553 ? -14.073 -15.694 29.880 1.00 16.61 ? 553 SER A O 1 ATOM 4380 C CB . SER A 1 553 ? -14.367 -16.695 26.835 1.00 16.52 ? 553 SER A CB 1 ATOM 4381 O OG . SER A 1 553 ? -15.765 -16.613 26.573 1.00 19.34 ? 553 SER A OG 1 ATOM 4382 N N . ILE A 1 554 ? -16.000 -16.818 29.592 1.00 16.87 ? 554 ILE A N 1 ATOM 4383 C CA . ILE A 1 554 ? -16.712 -15.966 30.534 1.00 15.88 ? 554 ILE A CA 1 ATOM 4384 C C . ILE A 1 554 ? -16.164 -15.960 31.978 1.00 15.23 ? 554 ILE A C 1 ATOM 4385 O O . ILE A 1 554 ? -15.949 -14.904 32.495 1.00 16.36 ? 554 ILE A O 1 ATOM 4386 C CB . ILE A 1 554 ? -18.280 -16.131 30.478 1.00 15.50 ? 554 ILE A CB 1 ATOM 4387 C CG1 . ILE A 1 554 ? -18.804 -15.781 29.072 1.00 16.34 ? 554 ILE A CG1 1 ATOM 4388 C CG2 . ILE A 1 554 ? -18.894 -15.229 31.519 1.00 12.64 ? 554 ILE A CG2 1 ATOM 4389 C CD1 . ILE A 1 554 ? -20.344 -15.916 28.858 1.00 17.22 ? 554 ILE A CD1 1 ATOM 4390 N N . PRO A 1 555 ? -15.961 -17.127 32.629 1.00 14.15 ? 555 PRO A N 1 ATOM 4391 C CA . PRO A 1 555 ? -15.407 -17.087 33.996 1.00 14.74 ? 555 PRO A CA 1 ATOM 4392 C C . PRO A 1 555 ? -13.977 -16.522 34.022 1.00 14.43 ? 555 PRO A C 1 ATOM 4393 O O . PRO A 1 555 ? -13.614 -15.850 34.975 1.00 13.98 ? 555 PRO A O 1 ATOM 4394 C CB . PRO A 1 555 ? -15.383 -18.565 34.432 1.00 13.60 ? 555 PRO A CB 1 ATOM 4395 C CG . PRO A 1 555 ? -16.183 -19.284 33.496 1.00 13.50 ? 555 PRO A CG 1 ATOM 4396 C CD . PRO A 1 555 ? -16.264 -18.503 32.213 1.00 15.08 ? 555 PRO A CD 1 ATOM 4397 N N . GLY A 1 556 ? -13.209 -16.758 32.961 1.00 14.66 ? 556 GLY A N 1 ATOM 4398 C CA . GLY A 1 556 ? -11.838 -16.200 32.843 1.00 13.67 ? 556 GLY A CA 1 ATOM 4399 C C . GLY A 1 556 ? -11.831 -14.688 32.826 1.00 14.04 ? 556 GLY A C 1 ATOM 4400 O O . GLY A 1 556 ? -11.012 -14.055 33.496 1.00 15.44 ? 556 GLY A O 1 ATOM 4401 N N . VAL A 1 557 ? -12.743 -14.104 32.048 1.00 13.99 ? 557 VAL A N 1 ATOM 4402 C CA . VAL A 1 557 ? -12.973 -12.662 32.051 1.00 13.15 ? 557 VAL A CA 1 ATOM 4403 C C . VAL A 1 557 ? -13.390 -12.117 33.433 1.00 12.91 ? 557 VAL A C 1 ATOM 4404 O O . VAL A 1 557 ? -12.806 -11.125 33.907 1.00 11.44 ? 557 VAL A O 1 ATOM 4405 C CB . VAL A 1 557 ? -13.985 -12.237 30.908 1.00 14.10 ? 557 VAL A CB 1 ATOM 4406 C CG1 . VAL A 1 557 ? -14.604 -10.862 31.168 1.00 11.92 ? 557 VAL A CG1 1 ATOM 4407 C CG2 . VAL A 1 557 ? -13.285 -12.239 29.553 1.00 11.65 ? 557 VAL A CG2 1 ATOM 4408 N N . LEU A 1 558 ? -14.422 -12.733 34.050 1.00 13.08 ? 558 LEU A N 1 ATOM 4409 C CA . LEU A 1 558 ? -14.900 -12.361 35.399 1.00 12.08 ? 558 LEU A CA 1 ATOM 4410 C C . LEU A 1 558 ? -13.788 -12.475 36.457 1.00 12.75 ? 558 LEU A C 1 ATOM 4411 O O . LEU A 1 558 ? -13.684 -11.658 37.329 1.00 12.93 ? 558 LEU A O 1 ATOM 4412 C CB . LEU A 1 558 ? -16.054 -13.261 35.804 1.00 12.12 ? 558 LEU A CB 1 ATOM 4413 C CG . LEU A 1 558 ? -17.302 -13.081 34.917 1.00 10.89 ? 558 LEU A CG 1 ATOM 4414 C CD1 . LEU A 1 558 ? -18.416 -13.855 35.496 1.00 11.32 ? 558 LEU A CD1 1 ATOM 4415 C CD2 . LEU A 1 558 ? -17.632 -11.569 34.821 1.00 11.55 ? 558 LEU A CD2 1 ATOM 4416 N N . GLU A 1 559 ? -12.992 -13.523 36.389 1.00 12.73 ? 559 GLU A N 1 ATOM 4417 C CA . GLU A 1 559 ? -11.918 -13.702 37.354 1.00 13.76 ? 559 GLU A CA 1 ATOM 4418 C C . GLU A 1 559 ? -10.878 -12.591 37.228 1.00 12.72 ? 559 GLU A C 1 ATOM 4419 O O . GLU A 1 559 ? -10.475 -12.065 38.225 1.00 13.35 ? 559 GLU A O 1 ATOM 4420 C CB . GLU A 1 559 ? -11.285 -15.089 37.213 1.00 14.42 ? 559 GLU A CB 1 ATOM 4421 C CG . GLU A 1 559 ? -12.209 -16.218 37.698 1.00 15.45 ? 559 GLU A CG 1 ATOM 4422 C CD . GLU A 1 559 ? -11.855 -17.557 37.075 1.00 21.00 ? 559 GLU A CD 1 ATOM 4423 O OE1 . GLU A 1 559 ? -11.003 -17.575 36.151 1.00 22.39 ? 559 GLU A OE1 1 ATOM 4424 O OE2 . GLU A 1 559 ? -12.401 -18.589 37.526 1.00 18.37 ? 559 GLU A OE2 1 ATOM 4425 N N . PHE A 1 560 ? -10.512 -12.172 36.025 1.00 12.18 ? 560 PHE A N 1 ATOM 4426 C CA . PHE A 1 560 ? -9.501 -11.102 35.929 1.00 13.33 ? 560 PHE A CA 1 ATOM 4427 C C . PHE A 1 560 ? -10.003 -9.739 36.380 1.00 12.95 ? 560 PHE A C 1 ATOM 4428 O O . PHE A 1 560 ? -9.195 -8.899 36.752 1.00 11.75 ? 560 PHE A O 1 ATOM 4429 C CB . PHE A 1 560 ? -8.850 -11.061 34.551 1.00 13.19 ? 560 PHE A CB 1 ATOM 4430 C CG . PHE A 1 560 ? -7.709 -12.009 34.449 1.00 14.01 ? 560 PHE A CG 1 ATOM 4431 C CD1 . PHE A 1 560 ? -7.929 -13.330 34.139 1.00 15.60 ? 560 PHE A CD1 1 ATOM 4432 C CD2 . PHE A 1 560 ? -6.405 -11.593 34.790 1.00 15.35 ? 560 PHE A CD2 1 ATOM 4433 C CE1 . PHE A 1 560 ? -6.862 -14.239 34.112 1.00 18.88 ? 560 PHE A CE1 1 ATOM 4434 C CE2 . PHE A 1 560 ? -5.349 -12.491 34.776 1.00 15.09 ? 560 PHE A CE2 1 ATOM 4435 C CZ . PHE A 1 560 ? -5.565 -13.795 34.424 1.00 14.80 ? 560 PHE A CZ 1 ATOM 4436 N N . ASN A 1 561 ? -11.330 -9.534 36.316 1.00 11.88 ? 561 ASN A N 1 ATOM 4437 C CA . ASN A 1 561 ? -11.986 -8.329 36.882 1.00 12.69 ? 561 ASN A CA 1 ATOM 4438 C C . ASN A 1 561 ? -11.839 -8.310 38.437 1.00 12.96 ? 561 ASN A C 1 ATOM 4439 O O . ASN A 1 561 ? -11.541 -7.279 39.029 1.00 15.87 ? 561 ASN A O 1 ATOM 4440 C CB . ASN A 1 561 ? -13.471 -8.210 36.362 1.00 11.26 ? 561 ASN A CB 1 ATOM 4441 C CG . ASN A 1 561 ? -13.584 -7.411 35.059 1.00 11.79 ? 561 ASN A CG 1 ATOM 4442 O OD1 . ASN A 1 561 ? -13.916 -6.226 35.073 1.00 10.98 ? 561 ASN A OD1 1 ATOM 4443 N ND2 . ASN A 1 561 ? -13.296 -8.054 33.929 1.00 12.77 ? 561 ASN A ND2 1 ATOM 4444 N N . LEU A 1 562 ? -11.947 -9.460 39.098 1.00 13.61 ? 562 LEU A N 1 ATOM 4445 C CA . LEU A 1 562 ? -11.567 -9.568 40.514 1.00 12.94 ? 562 LEU A CA 1 ATOM 4446 C C . LEU A 1 562 ? -10.090 -9.275 40.777 1.00 13.62 ? 562 LEU A C 1 ATOM 4447 O O . LEU A 1 562 ? -9.756 -8.707 41.793 1.00 14.43 ? 562 LEU A O 1 ATOM 4448 C CB . LEU A 1 562 ? -11.838 -10.963 41.030 1.00 13.47 ? 562 LEU A CB 1 ATOM 4449 C CG . LEU A 1 562 ? -13.180 -11.665 40.846 1.00 16.46 ? 562 LEU A CG 1 ATOM 4450 C CD1 . LEU A 1 562 ? -13.034 -13.055 41.473 1.00 14.40 ? 562 LEU A CD1 1 ATOM 4451 C CD2 . LEU A 1 562 ? -14.303 -10.865 41.522 1.00 14.17 ? 562 LEU A CD2 1 ATOM 4452 N N . PHE A 1 563 ? -9.212 -9.673 39.863 1.00 13.18 ? 563 PHE A N 1 ATOM 4453 C CA . PHE A 1 563 ? -7.760 -9.487 40.056 1.00 13.29 ? 563 PHE A CA 1 ATOM 4454 C C . PHE A 1 563 ? -7.326 -8.060 39.702 1.00 13.80 ? 563 PHE A C 1 ATOM 4455 O O . PHE A 1 563 ? -6.138 -7.697 39.790 1.00 13.90 ? 563 PHE A O 1 ATOM 4456 C CB . PHE A 1 563 ? -6.989 -10.496 39.187 1.00 13.08 ? 563 PHE A CB 1 ATOM 4457 C CG . PHE A 1 563 ? -7.374 -11.939 39.421 1.00 11.77 ? 563 PHE A CG 1 ATOM 4458 C CD1 . PHE A 1 563 ? -7.777 -12.393 40.685 1.00 12.86 ? 563 PHE A CD1 1 ATOM 4459 C CD2 . PHE A 1 563 ? -7.302 -12.849 38.377 1.00 11.11 ? 563 PHE A CD2 1 ATOM 4460 C CE1 . PHE A 1 563 ? -8.105 -13.704 40.883 1.00 11.91 ? 563 PHE A CE1 1 ATOM 4461 C CE2 . PHE A 1 563 ? -7.597 -14.154 38.554 1.00 13.57 ? 563 PHE A CE2 1 ATOM 4462 C CZ . PHE A 1 563 ? -8.025 -14.602 39.822 1.00 13.68 ? 563 PHE A CZ 1 ATOM 4463 N N . GLY A 1 564 ? -8.297 -7.243 39.285 1.00 13.12 ? 564 GLY A N 1 ATOM 4464 C CA . GLY A 1 564 ? -8.040 -5.857 38.916 1.00 12.47 ? 564 GLY A CA 1 ATOM 4465 C C . GLY A 1 564 ? -7.419 -5.645 37.557 1.00 12.64 ? 564 GLY A C 1 ATOM 4466 O O . GLY A 1 564 ? -6.710 -4.678 37.353 1.00 13.11 ? 564 GLY A O 1 ATOM 4467 N N . ILE A 1 565 ? -7.644 -6.576 36.639 1.00 12.33 ? 565 ILE A N 1 ATOM 4468 C CA . ILE A 1 565 ? -7.254 -6.429 35.253 1.00 12.64 ? 565 ILE A CA 1 ATOM 4469 C C . ILE A 1 565 ? -8.563 -6.480 34.467 1.00 13.21 ? 565 ILE A C 1 ATOM 4470 O O . ILE A 1 565 ? -8.838 -7.473 33.826 1.00 13.40 ? 565 ILE A O 1 ATOM 4471 C CB . ILE A 1 565 ? -6.328 -7.608 34.844 1.00 13.20 ? 565 ILE A CB 1 ATOM 4472 C CG1 . ILE A 1 565 ? -5.173 -7.717 35.845 1.00 12.99 ? 565 ILE A CG1 1 ATOM 4473 C CG2 . ILE A 1 565 ? -5.843 -7.456 33.418 1.00 13.03 ? 565 ILE A CG2 1 ATOM 4474 C CD1 . ILE A 1 565 ? -4.206 -8.818 35.564 1.00 18.08 ? 565 ILE A CD1 1 ATOM 4475 N N . PRO A 1 566 ? -9.386 -5.410 34.561 1.00 13.28 ? 566 PRO A N 1 ATOM 4476 C CA . PRO A 1 566 ? -10.710 -5.489 33.966 1.00 13.79 ? 566 PRO A CA 1 ATOM 4477 C C . PRO A 1 566 ? -10.692 -5.532 32.447 1.00 13.93 ? 566 PRO A C 1 ATOM 4478 O O . PRO A 1 566 ? -11.665 -6.007 31.847 1.00 13.20 ? 566 PRO A O 1 ATOM 4479 C CB . PRO A 1 566 ? -11.399 -4.213 34.471 1.00 12.42 ? 566 PRO A CB 1 ATOM 4480 C CG . PRO A 1 566 ? -10.330 -3.257 34.682 1.00 13.02 ? 566 PRO A CG 1 ATOM 4481 C CD . PRO A 1 566 ? -9.162 -4.098 35.205 1.00 12.81 ? 566 PRO A CD 1 ATOM 4482 N N . MET A 1 567 ? -9.629 -4.996 31.837 1.00 14.28 ? 567 MET A N 1 ATOM 4483 C CA . MET A 1 567 ? -9.474 -5.033 30.394 1.00 15.11 ? 567 MET A CA 1 ATOM 4484 C C . MET A 1 567 ? -8.876 -6.379 29.974 1.00 14.25 ? 567 MET A C 1 ATOM 4485 O O . MET A 1 567 ? -7.626 -6.569 29.902 1.00 13.89 ? 567 MET A O 1 ATOM 4486 C CB . MET A 1 567 ? -8.672 -3.827 29.868 1.00 14.85 ? 567 MET A CB 1 ATOM 4487 C CG . MET A 1 567 ? -8.627 -3.801 28.332 1.00 17.02 ? 567 MET A CG 1 ATOM 4488 S SD . MET A 1 567 ? -8.156 -2.257 27.588 1.00 21.25 ? 567 MET A SD 1 ATOM 4489 C CE . MET A 1 567 ? -9.716 -1.386 27.505 1.00 19.12 ? 567 MET A CE 1 ATOM 4490 N N . VAL A 1 568 ? -9.780 -7.328 29.739 1.00 12.35 ? 568 VAL A N 1 ATOM 4491 C CA . VAL A 1 568 ? -9.434 -8.716 29.530 1.00 13.21 ? 568 VAL A CA 1 ATOM 4492 C C . VAL A 1 568 ? -10.448 -9.295 28.573 1.00 13.90 ? 568 VAL A C 1 ATOM 4493 O O . VAL A 1 568 ? -11.640 -8.969 28.639 1.00 14.39 ? 568 VAL A O 1 ATOM 4494 C CB . VAL A 1 568 ? -9.363 -9.521 30.931 1.00 13.51 ? 568 VAL A CB 1 ATOM 4495 C CG1 . VAL A 1 568 ? -10.682 -9.467 31.683 1.00 11.60 ? 568 VAL A CG1 1 ATOM 4496 C CG2 . VAL A 1 568 ? -8.881 -10.995 30.780 1.00 12.00 ? 568 VAL A CG2 1 ATOM 4497 N N . GLY A 1 569 ? -9.977 -10.148 27.673 1.00 14.43 ? 569 GLY A N 1 ATOM 4498 C CA . GLY A 1 569 ? -10.854 -11.005 26.894 1.00 13.78 ? 569 GLY A CA 1 ATOM 4499 C C . GLY A 1 569 ? -10.051 -12.097 26.203 1.00 14.83 ? 569 GLY A C 1 ATOM 4500 O O . GLY A 1 569 ? -8.806 -12.119 26.309 1.00 14.64 ? 569 GLY A O 1 ATOM 4501 N N . PRO A 1 570 ? -10.741 -13.020 25.524 1.00 14.57 ? 570 PRO A N 1 ATOM 4502 C CA . PRO A 1 570 ? -10.030 -14.024 24.755 1.00 15.94 ? 570 PRO A CA 1 ATOM 4503 C C . PRO A 1 570 ? -9.710 -13.549 23.316 1.00 16.20 ? 570 PRO A C 1 ATOM 4504 O O . PRO A 1 570 ? -9.932 -12.361 22.946 1.00 16.51 ? 570 PRO A O 1 ATOM 4505 C CB . PRO A 1 570 ? -11.028 -15.172 24.709 1.00 14.87 ? 570 PRO A CB 1 ATOM 4506 C CG . PRO A 1 570 ? -12.402 -14.417 24.545 1.00 14.78 ? 570 PRO A CG 1 ATOM 4507 C CD . PRO A 1 570 ? -12.219 -13.197 25.445 1.00 16.12 ? 570 PRO A CD 1 ATOM 4508 N N . ASP A 1 571 ? -9.178 -14.473 22.528 1.00 16.83 ? 571 ASP A N 1 ATOM 4509 C CA . ASP A 1 571 ? -9.097 -14.323 21.079 1.00 16.96 ? 571 ASP A CA 1 ATOM 4510 C C . ASP A 1 571 ? -10.468 -14.737 20.570 1.00 17.08 ? 571 ASP A C 1 ATOM 4511 O O . ASP A 1 571 ? -10.827 -15.909 20.636 1.00 17.36 ? 571 ASP A O 1 ATOM 4512 C CB . ASP A 1 571 ? -8.015 -15.235 20.515 1.00 16.45 ? 571 ASP A CB 1 ATOM 4513 C CG . ASP A 1 571 ? -6.596 -14.746 20.840 1.00 17.93 ? 571 ASP A CG 1 ATOM 4514 O OD1 . ASP A 1 571 ? -6.438 -13.598 21.282 1.00 18.67 ? 571 ASP A OD1 1 ATOM 4515 O OD2 . ASP A 1 571 ? -5.630 -15.524 20.686 1.00 18.26 ? 571 ASP A OD2 1 ATOM 4516 N N . ILE A 1 572 ? -11.239 -13.751 20.124 1.00 17.39 ? 572 ILE A N 1 ATOM 4517 C CA . ILE A 1 572 ? -12.571 -13.952 19.613 1.00 17.82 ? 572 ILE A CA 1 ATOM 4518 C C . ILE A 1 572 ? -12.420 -14.807 18.372 1.00 18.43 ? 572 ILE A C 1 ATOM 4519 O O . ILE A 1 572 ? -11.515 -14.565 17.546 1.00 17.44 ? 572 ILE A O 1 ATOM 4520 C CB . ILE A 1 572 ? -13.289 -12.623 19.240 1.00 18.01 ? 572 ILE A CB 1 ATOM 4521 C CG1 . ILE A 1 572 ? -13.508 -11.742 20.470 1.00 17.47 ? 572 ILE A CG1 1 ATOM 4522 C CG2 . ILE A 1 572 ? -14.633 -12.922 18.542 1.00 19.34 ? 572 ILE A CG2 1 ATOM 4523 C CD1 . ILE A 1 572 ? -14.233 -10.415 20.188 1.00 17.27 ? 572 ILE A CD1 1 ATOM 4524 N N . CYS A 1 573 ? -13.295 -15.812 18.280 1.00 18.01 ? 573 CYS A N 1 ATOM 4525 C CA . CYS A 1 573 ? -13.319 -16.812 17.210 1.00 18.91 ? 573 CYS A CA 1 ATOM 4526 C C . CYS A 1 573 ? -12.302 -17.939 17.401 1.00 18.31 ? 573 CYS A C 1 ATOM 4527 O O . CYS A 1 573 ? -12.392 -18.972 16.758 1.00 18.98 ? 573 CYS A O 1 ATOM 4528 C CB . CYS A 1 573 ? -13.276 -16.195 15.805 1.00 19.40 ? 573 CYS A CB 1 ATOM 4529 S SG . CYS A 1 573 ? -14.727 -15.125 15.551 1.00 21.24 ? 573 CYS A SG 1 ATOM 4530 N N . GLY A 1 574 ? -11.395 -17.767 18.343 1.00 17.66 ? 574 GLY A N 1 ATOM 4531 C CA . GLY A 1 574 ? -10.519 -18.850 18.711 1.00 17.68 ? 574 GLY A CA 1 ATOM 4532 C C . GLY A 1 574 ? -9.237 -18.751 17.941 1.00 17.63 ? 574 GLY A C 1 ATOM 4533 O O . GLY A 1 574 ? -9.242 -18.680 16.725 1.00 18.68 ? 574 GLY A O 1 ATOM 4534 N N . PHE A 1 575 ? -8.143 -18.718 18.674 1.00 17.50 ? 575 PHE A N 1 ATOM 4535 C CA . PHE A 1 575 ? -6.814 -18.681 18.094 1.00 17.63 ? 575 PHE A CA 1 ATOM 4536 C C . PHE A 1 575 ? -6.511 -19.903 17.209 1.00 18.35 ? 575 PHE A C 1 ATOM 4537 O O . PHE A 1 575 ? -6.375 -19.767 16.008 1.00 18.59 ? 575 PHE A O 1 ATOM 4538 C CB . PHE A 1 575 ? -5.827 -18.573 19.234 1.00 17.17 ? 575 PHE A CB 1 ATOM 4539 C CG . PHE A 1 575 ? -4.390 -18.502 18.814 1.00 17.13 ? 575 PHE A CG 1 ATOM 4540 C CD1 . PHE A 1 575 ? -3.871 -17.351 18.234 1.00 15.46 ? 575 PHE A CD1 1 ATOM 4541 C CD2 . PHE A 1 575 ? -3.546 -19.569 19.067 1.00 16.70 ? 575 PHE A CD2 1 ATOM 4542 C CE1 . PHE A 1 575 ? -2.532 -17.271 17.900 1.00 18.35 ? 575 PHE A CE1 1 ATOM 4543 C CE2 . PHE A 1 575 ? -2.203 -19.511 18.710 1.00 16.47 ? 575 PHE A CE2 1 ATOM 4544 C CZ . PHE A 1 575 ? -1.689 -18.362 18.140 1.00 16.84 ? 575 PHE A CZ 1 ATOM 4545 N N . ALA A 1 576 ? -6.426 -21.091 17.802 1.00 19.15 ? 576 ALA A N 1 ATOM 4546 C CA . ALA A 1 576 ? -6.044 -22.285 17.059 1.00 20.20 ? 576 ALA A CA 1 ATOM 4547 C C . ALA A 1 576 ? -7.245 -22.845 16.319 1.00 20.76 ? 576 ALA A C 1 ATOM 4548 O O . ALA A 1 576 ? -8.366 -22.787 16.827 1.00 20.46 ? 576 ALA A O 1 ATOM 4549 C CB . ALA A 1 576 ? -5.464 -23.345 18.001 1.00 19.69 ? 576 ALA A CB 1 ATOM 4550 N N . LEU A 1 577 ? -6.987 -23.358 15.114 1.00 21.41 ? 577 LEU A N 1 ATOM 4551 C CA . LEU A 1 577 ? -7.972 -24.054 14.296 1.00 22.12 ? 577 LEU A CA 1 ATOM 4552 C C . LEU A 1 577 ? -8.749 -23.099 13.400 1.00 22.20 ? 577 LEU A C 1 ATOM 4553 O O . LEU A 1 577 ? -8.835 -21.907 13.685 1.00 22.04 ? 577 LEU A O 1 ATOM 4554 C CB . LEU A 1 577 ? -8.938 -24.888 15.166 1.00 21.95 ? 577 LEU A CB 1 ATOM 4555 C CG . LEU A 1 577 ? -8.570 -26.320 15.530 1.00 23.60 ? 577 LEU A CG 1 ATOM 4556 C CD1 . LEU A 1 577 ? -7.089 -26.548 15.747 1.00 24.47 ? 577 LEU A CD1 1 ATOM 4557 C CD2 . LEU A 1 577 ? -9.402 -26.820 16.687 1.00 23.20 ? 577 LEU A CD2 1 ATOM 4558 N N . ASP A 1 578 ? -9.309 -23.643 12.318 1.00 21.80 ? 578 ASP A N 1 ATOM 4559 C CA . ASP A 1 578 ? -10.213 -22.916 11.448 1.00 22.33 ? 578 ASP A CA 1 ATOM 4560 C C . ASP A 1 578 ? -11.521 -22.769 12.228 1.00 21.90 ? 578 ASP A C 1 ATOM 4561 O O . ASP A 1 578 ? -11.970 -23.732 12.834 1.00 21.55 ? 578 ASP A O 1 ATOM 4562 C CB . ASP A 1 578 ? -10.488 -23.715 10.164 1.00 22.28 ? 578 ASP A CB 1 ATOM 4563 C CG . ASP A 1 578 ? -9.242 -23.878 9.275 1.00 24.23 ? 578 ASP A CG 1 ATOM 4564 O OD1 . ASP A 1 578 ? -8.242 -23.146 9.438 1.00 25.09 ? 578 ASP A OD1 1 ATOM 4565 O OD2 . ASP A 1 578 ? -9.267 -24.749 8.392 1.00 26.75 ? 578 ASP A OD2 1 ATOM 4566 N N . THR A 1 579 ? -12.108 -21.578 12.236 1.00 20.98 ? 579 THR A N 1 ATOM 4567 C CA . THR A 1 579 ? -13.308 -21.357 13.042 1.00 22.01 ? 579 THR A CA 1 ATOM 4568 C C . THR A 1 579 ? -14.565 -21.580 12.211 1.00 21.55 ? 579 THR A C 1 ATOM 4569 O O . THR A 1 579 ? -14.684 -21.023 11.140 1.00 21.35 ? 579 THR A O 1 ATOM 4570 C CB . THR A 1 579 ? -13.313 -19.947 13.694 1.00 22.10 ? 579 THR A CB 1 ATOM 4571 O OG1 . THR A 1 579 ? -14.247 -19.915 14.776 1.00 24.18 ? 579 THR A OG1 1 ATOM 4572 C CG2 . THR A 1 579 ? -13.657 -18.847 12.682 1.00 21.99 ? 579 THR A CG2 1 ATOM 4573 N N . PRO A 1 580 ? -15.500 -22.410 12.698 1.00 22.31 ? 580 PRO A N 1 ATOM 4574 C CA . PRO A 1 580 ? -16.776 -22.552 11.967 1.00 21.94 ? 580 PRO A CA 1 ATOM 4575 C C . PRO A 1 580 ? -17.518 -21.223 11.916 1.00 21.51 ? 580 PRO A C 1 ATOM 4576 O O . PRO A 1 580 ? -17.484 -20.452 12.874 1.00 20.95 ? 580 PRO A O 1 ATOM 4577 C CB . PRO A 1 580 ? -17.574 -23.522 12.832 1.00 22.66 ? 580 PRO A CB 1 ATOM 4578 C CG . PRO A 1 580 ? -16.540 -24.222 13.677 1.00 22.23 ? 580 PRO A CG 1 ATOM 4579 C CD . PRO A 1 580 ? -15.472 -23.230 13.922 1.00 21.87 ? 580 PRO A CD 1 ATOM 4580 N N . GLU A 1 581 ? -18.180 -20.936 10.810 1.00 21.00 ? 581 GLU A N 1 ATOM 4581 C CA . GLU A 1 581 ? -18.961 -19.707 10.740 1.00 21.24 ? 581 GLU A CA 1 ATOM 4582 C C . GLU A 1 581 ? -19.913 -19.490 11.961 1.00 20.52 ? 581 GLU A C 1 ATOM 4583 O O . GLU A 1 581 ? -20.036 -18.374 12.457 1.00 19.70 ? 581 GLU A O 1 ATOM 4584 C CB . GLU A 1 581 ? -19.712 -19.638 9.416 1.00 20.80 ? 581 GLU A CB 1 ATOM 4585 C CG . GLU A 1 581 ? -20.335 -18.285 9.139 1.00 21.88 ? 581 GLU A CG 1 ATOM 4586 C CD . GLU A 1 581 ? -21.740 -18.143 9.716 1.00 24.47 ? 581 GLU A CD 1 ATOM 4587 O OE1 . GLU A 1 581 ? -22.334 -19.126 10.230 1.00 25.60 ? 581 GLU A OE1 1 ATOM 4588 O OE2 . GLU A 1 581 ? -22.254 -17.019 9.675 1.00 26.36 ? 581 GLU A OE2 1 ATOM 4589 N N . GLU A 1 582 ? -20.596 -20.534 12.431 1.00 20.59 ? 582 GLU A N 1 ATOM 4590 C CA . GLU A 1 582 ? -21.647 -20.325 13.441 1.00 21.08 ? 582 GLU A CA 1 ATOM 4591 C C . GLU A 1 582 ? -21.007 -19.966 14.785 1.00 20.41 ? 582 GLU A C 1 ATOM 4592 O O . GLU A 1 582 ? -21.472 -19.058 15.479 1.00 19.36 ? 582 GLU A O 1 ATOM 4593 C CB . GLU A 1 582 ? -22.561 -21.545 13.585 1.00 21.15 ? 582 GLU A CB 1 ATOM 4594 C CG . GLU A 1 582 ? -23.643 -21.448 14.672 1.00 20.47 ? 582 GLU A CG 1 ATOM 4595 C CD . GLU A 1 582 ? -24.186 -22.814 15.073 1.00 23.29 ? 582 GLU A CD 1 ATOM 4596 O OE1 . GLU A 1 582 ? -23.768 -23.841 14.476 1.00 26.63 ? 582 GLU A OE1 1 ATOM 4597 O OE2 . GLU A 1 582 ? -25.007 -22.890 16.015 1.00 24.97 ? 582 GLU A OE2 1 ATOM 4598 N N . LEU A 1 583 ? -19.918 -20.662 15.106 1.00 19.89 ? 583 LEU A N 1 ATOM 4599 C CA . LEU A 1 583 ? -19.141 -20.375 16.294 1.00 19.75 ? 583 LEU A CA 1 ATOM 4600 C C . LEU A 1 583 ? -18.629 -18.934 16.256 1.00 19.75 ? 583 LEU A C 1 ATOM 4601 O O . LEU A 1 583 ? -18.895 -18.173 17.174 1.00 20.42 ? 583 LEU A O 1 ATOM 4602 C CB . LEU A 1 583 ? -17.967 -21.382 16.464 1.00 18.90 ? 583 LEU A CB 1 ATOM 4603 C CG . LEU A 1 583 ? -16.988 -21.069 17.608 1.00 18.89 ? 583 LEU A CG 1 ATOM 4604 C CD1 . LEU A 1 583 ? -17.622 -21.153 18.979 1.00 17.84 ? 583 LEU A CD1 1 ATOM 4605 C CD2 . LEU A 1 583 ? -15.692 -21.920 17.538 1.00 18.77 ? 583 LEU A CD2 1 ATOM 4606 N N . CYS A 1 584 ? -17.946 -18.547 15.176 1.00 20.58 ? 584 CYS A N 1 ATOM 4607 C CA . CYS A 1 584 ? -17.366 -17.206 15.066 1.00 19.95 ? 584 CYS A CA 1 ATOM 4608 C C . CYS A 1 584 ? -18.448 -16.130 15.123 1.00 19.17 ? 584 CYS A C 1 ATOM 4609 O O . CYS A 1 584 ? -18.282 -15.118 15.749 1.00 19.46 ? 584 CYS A O 1 ATOM 4610 C CB . CYS A 1 584 ? -16.507 -17.065 13.804 1.00 20.03 ? 584 CYS A CB 1 ATOM 4611 S SG . CYS A 1 584 ? -15.461 -15.576 13.678 1.00 22.54 ? 584 CYS A SG 1 ATOM 4612 N N . ARG A 1 585 ? -19.584 -16.381 14.506 1.00 19.02 ? 585 ARG A N 1 ATOM 4613 C CA . ARG A 1 585 ? -20.702 -15.463 14.626 1.00 17.85 ? 585 ARG A CA 1 ATOM 4614 C C . ARG A 1 585 ? -21.180 -15.248 16.071 1.00 17.62 ? 585 ARG A C 1 ATOM 4615 O O . ARG A 1 585 ? -21.382 -14.107 16.483 1.00 17.95 ? 585 ARG A O 1 ATOM 4616 C CB . ARG A 1 585 ? -21.848 -15.953 13.749 1.00 18.25 ? 585 ARG A CB 1 ATOM 4617 C CG . ARG A 1 585 ? -23.107 -15.096 13.845 1.00 17.67 ? 585 ARG A CG 1 ATOM 4618 C CD . ARG A 1 585 ? -24.001 -15.292 12.626 1.00 17.03 ? 585 ARG A CD 1 ATOM 4619 N NE . ARG A 1 585 ? -24.030 -16.668 12.147 1.00 17.45 ? 585 ARG A NE 1 ATOM 4620 C CZ . ARG A 1 585 ? -24.776 -17.644 12.660 1.00 19.11 ? 585 ARG A CZ 1 ATOM 4621 N NH1 . ARG A 1 585 ? -25.576 -17.416 13.703 1.00 24.92 ? 585 ARG A NH1 1 ATOM 4622 N NH2 . ARG A 1 585 ? -24.715 -18.856 12.136 1.00 18.37 ? 585 ARG A NH2 1 ATOM 4623 N N . ARG A 1 586 ? -21.387 -16.335 16.819 1.00 17.29 ? 586 ARG A N 1 ATOM 4624 C CA . ARG A 1 586 ? -21.783 -16.255 18.244 1.00 15.92 ? 586 ARG A CA 1 ATOM 4625 C C . ARG A 1 586 ? -20.650 -15.683 19.083 1.00 15.78 ? 586 ARG A C 1 ATOM 4626 O O . ARG A 1 586 ? -20.871 -14.916 20.026 1.00 14.61 ? 586 ARG A O 1 ATOM 4627 C CB . ARG A 1 586 ? -22.198 -17.629 18.787 1.00 15.78 ? 586 ARG A CB 1 ATOM 4628 C CG . ARG A 1 586 ? -23.473 -18.210 18.202 1.00 15.85 ? 586 ARG A CG 1 ATOM 4629 C CD . ARG A 1 586 ? -24.593 -17.223 18.161 1.00 16.85 ? 586 ARG A CD 1 ATOM 4630 N NE . ARG A 1 586 ? -25.861 -17.914 18.026 1.00 16.55 ? 586 ARG A NE 1 ATOM 4631 C CZ . ARG A 1 586 ? -27.040 -17.309 18.010 1.00 16.47 ? 586 ARG A CZ 1 ATOM 4632 N NH1 . ARG A 1 586 ? -27.093 -16.007 18.112 1.00 13.97 ? 586 ARG A NH1 1 ATOM 4633 N NH2 . ARG A 1 586 ? -28.167 -18.028 17.895 1.00 18.08 ? 586 ARG A NH2 1 ATOM 4634 N N . TRP A 1 587 ? -19.412 -16.051 18.731 1.00 16.19 ? 587 TRP A N 1 ATOM 4635 C CA . TRP A 1 587 ? -18.281 -15.504 19.421 1.00 15.20 ? 587 TRP A CA 1 ATOM 4636 C C . TRP A 1 587 ? -18.153 -14.017 19.176 1.00 15.36 ? 587 TRP A C 1 ATOM 4637 O O . TRP A 1 587 ? -17.874 -13.280 20.099 1.00 16.42 ? 587 TRP A O 1 ATOM 4638 C CB . TRP A 1 587 ? -16.969 -16.254 19.070 1.00 15.44 ? 587 TRP A CB 1 ATOM 4639 C CG . TRP A 1 587 ? -16.043 -16.356 20.260 1.00 15.37 ? 587 TRP A CG 1 ATOM 4640 C CD1 . TRP A 1 587 ? -15.897 -15.445 21.302 1.00 15.75 ? 587 TRP A CD1 1 ATOM 4641 C CD2 . TRP A 1 587 ? -15.142 -17.424 20.538 1.00 15.82 ? 587 TRP A CD2 1 ATOM 4642 N NE1 . TRP A 1 587 ? -14.950 -15.899 22.201 1.00 14.02 ? 587 TRP A NE1 1 ATOM 4643 C CE2 . TRP A 1 587 ? -14.468 -17.107 21.750 1.00 15.89 ? 587 TRP A CE2 1 ATOM 4644 C CE3 . TRP A 1 587 ? -14.849 -18.634 19.890 1.00 13.53 ? 587 TRP A CE3 1 ATOM 4645 C CZ2 . TRP A 1 587 ? -13.499 -17.957 22.311 1.00 14.78 ? 587 TRP A CZ2 1 ATOM 4646 C CZ3 . TRP A 1 587 ? -13.866 -19.474 20.448 1.00 15.71 ? 587 TRP A CZ3 1 ATOM 4647 C CH2 . TRP A 1 587 ? -13.217 -19.126 21.643 1.00 15.37 ? 587 TRP A CH2 1 ATOM 4648 N N . MET A 1 588 ? -18.377 -13.541 17.951 1.00 16.09 ? 588 MET A N 1 ATOM 4649 C CA . MET A 1 588 ? -18.352 -12.079 17.706 1.00 15.49 ? 588 MET A CA 1 ATOM 4650 C C . MET A 1 588 ? -19.505 -11.323 18.392 1.00 15.24 ? 588 MET A C 1 ATOM 4651 O O . MET A 1 588 ? -19.342 -10.201 18.854 1.00 13.98 ? 588 MET A O 1 ATOM 4652 C CB . MET A 1 588 ? -18.345 -11.764 16.199 1.00 15.89 ? 588 MET A CB 1 ATOM 4653 C CG . MET A 1 588 ? -17.016 -11.943 15.498 1.00 16.51 ? 588 MET A CG 1 ATOM 4654 S SD . MET A 1 588 ? -15.727 -10.776 16.008 1.00 16.06 ? 588 MET A SD 1 ATOM 4655 C CE . MET A 1 588 ? -16.304 -9.127 15.652 1.00 15.86 ? 588 MET A CE 1 ATOM 4656 N N . GLN A 1 589 ? -20.684 -11.926 18.443 1.00 14.67 ? 589 GLN A N 1 ATOM 4657 C CA . GLN A 1 589 ? -21.806 -11.320 19.200 1.00 15.23 ? 589 GLN A CA 1 ATOM 4658 C C . GLN A 1 589 ? -21.510 -11.106 20.677 1.00 15.49 ? 589 GLN A C 1 ATOM 4659 O O . GLN A 1 589 ? -21.748 -10.013 21.209 1.00 16.00 ? 589 GLN A O 1 ATOM 4660 C CB . GLN A 1 589 ? -23.053 -12.193 19.064 1.00 15.07 ? 589 GLN A CB 1 ATOM 4661 C CG . GLN A 1 589 ? -23.578 -12.159 17.653 1.00 15.91 ? 589 GLN A CG 1 ATOM 4662 C CD . GLN A 1 589 ? -24.626 -13.227 17.371 1.00 18.20 ? 589 GLN A CD 1 ATOM 4663 O OE1 . GLN A 1 589 ? -24.957 -14.061 18.225 1.00 15.22 ? 589 GLN A OE1 1 ATOM 4664 N NE2 . GLN A 1 589 ? -25.155 -13.195 16.173 1.00 19.63 ? 589 GLN A NE2 1 ATOM 4665 N N . LEU A 1 590 ? -20.996 -12.152 21.328 1.00 15.75 ? 590 LEU A N 1 ATOM 4666 C CA . LEU A 1 590 ? -20.496 -12.086 22.700 1.00 16.35 ? 590 LEU A CA 1 ATOM 4667 C C . LEU A 1 590 ? -19.285 -11.163 22.794 1.00 15.68 ? 590 LEU A C 1 ATOM 4668 O O . LEU A 1 590 ? -19.197 -10.340 23.706 1.00 16.28 ? 590 LEU A O 1 ATOM 4669 C CB . LEU A 1 590 ? -20.109 -13.486 23.233 1.00 15.43 ? 590 LEU A CB 1 ATOM 4670 C CG . LEU A 1 590 ? -19.393 -13.531 24.594 1.00 16.35 ? 590 LEU A CG 1 ATOM 4671 C CD1 . LEU A 1 590 ? -20.164 -12.840 25.741 1.00 12.06 ? 590 LEU A CD1 1 ATOM 4672 C CD2 . LEU A 1 590 ? -19.018 -14.923 25.017 1.00 17.25 ? 590 LEU A CD2 1 ATOM 4673 N N . GLY A 1 591 ? -18.358 -11.324 21.859 1.00 15.75 ? 591 GLY A N 1 ATOM 4674 C CA . GLY A 1 591 ? -17.058 -10.611 21.886 1.00 14.77 ? 591 GLY A CA 1 ATOM 4675 C C . GLY A 1 591 ? -17.125 -9.096 21.799 1.00 14.61 ? 591 GLY A C 1 ATOM 4676 O O . GLY A 1 591 ? -16.176 -8.388 22.209 1.00 13.31 ? 591 GLY A O 1 ATOM 4677 N N . ALA A 1 592 ? -18.245 -8.576 21.270 1.00 13.67 ? 592 ALA A N 1 ATOM 4678 C CA . ALA A 1 592 ? -18.475 -7.134 21.241 1.00 13.08 ? 592 ALA A CA 1 ATOM 4679 C C . ALA A 1 592 ? -18.642 -6.595 22.664 1.00 13.51 ? 592 ALA A C 1 ATOM 4680 O O . ALA A 1 592 ? -18.579 -5.386 22.905 1.00 13.23 ? 592 ALA A O 1 ATOM 4681 C CB . ALA A 1 592 ? -19.720 -6.800 20.360 1.00 14.02 ? 592 ALA A CB 1 ATOM 4682 N N . PHE A 1 593 ? -18.837 -7.498 23.620 1.00 13.38 ? 593 PHE A N 1 ATOM 4683 C CA . PHE A 1 593 ? -19.039 -7.110 25.021 1.00 14.14 ? 593 PHE A CA 1 ATOM 4684 C C . PHE A 1 593 ? -17.947 -7.540 26.018 1.00 14.34 ? 593 PHE A C 1 ATOM 4685 O O . PHE A 1 593 ? -18.088 -7.338 27.219 1.00 14.46 ? 593 PHE A O 1 ATOM 4686 C CB . PHE A 1 593 ? -20.462 -7.534 25.444 1.00 14.82 ? 593 PHE A CB 1 ATOM 4687 C CG . PHE A 1 593 ? -21.497 -6.881 24.597 1.00 14.41 ? 593 PHE A CG 1 ATOM 4688 C CD1 . PHE A 1 593 ? -21.890 -5.559 24.861 1.00 16.01 ? 593 PHE A CD1 1 ATOM 4689 C CD2 . PHE A 1 593 ? -21.979 -7.520 23.463 1.00 14.43 ? 593 PHE A CD2 1 ATOM 4690 C CE1 . PHE A 1 593 ? -22.795 -4.896 24.038 1.00 12.38 ? 593 PHE A CE1 1 ATOM 4691 C CE2 . PHE A 1 593 ? -22.899 -6.876 22.630 1.00 14.98 ? 593 PHE A CE2 1 ATOM 4692 C CZ . PHE A 1 593 ? -23.296 -5.553 22.918 1.00 15.75 ? 593 PHE A CZ 1 ATOM 4693 N N . TYR A 1 594 ? -16.858 -8.138 25.526 1.00 14.38 ? 594 TYR A N 1 ATOM 4694 C CA . TYR A 1 594 ? -15.682 -8.375 26.386 1.00 14.52 ? 594 TYR A CA 1 ATOM 4695 C C . TYR A 1 594 ? -15.060 -7.020 26.650 1.00 15.27 ? 594 TYR A C 1 ATOM 4696 O O . TYR A 1 594 ? -14.989 -6.203 25.738 1.00 17.49 ? 594 TYR A O 1 ATOM 4697 C CB . TYR A 1 594 ? -14.643 -9.253 25.688 1.00 12.45 ? 594 TYR A CB 1 ATOM 4698 C CG . TYR A 1 594 ? -14.996 -10.712 25.507 1.00 10.95 ? 594 TYR A CG 1 ATOM 4699 C CD1 . TYR A 1 594 ? -15.469 -11.504 26.561 1.00 11.45 ? 594 TYR A CD1 1 ATOM 4700 C CD2 . TYR A 1 594 ? -14.778 -11.313 24.290 1.00 9.12 ? 594 TYR A CD2 1 ATOM 4701 C CE1 . TYR A 1 594 ? -15.720 -12.889 26.361 1.00 7.93 ? 594 TYR A CE1 1 ATOM 4702 C CE2 . TYR A 1 594 ? -15.025 -12.641 24.081 1.00 8.67 ? 594 TYR A CE2 1 ATOM 4703 C CZ . TYR A 1 594 ? -15.496 -13.412 25.096 1.00 8.11 ? 594 TYR A CZ 1 ATOM 4704 O OH . TYR A 1 594 ? -15.722 -14.717 24.787 1.00 11.22 ? 594 TYR A OH 1 ATOM 4705 N N . PRO A 1 595 ? -14.605 -6.760 27.881 1.00 15.69 ? 595 PRO A N 1 ATOM 4706 C CA . PRO A 1 595 ? -14.039 -5.432 28.098 1.00 15.97 ? 595 PRO A CA 1 ATOM 4707 C C . PRO A 1 595 ? -12.798 -5.162 27.196 1.00 16.59 ? 595 PRO A C 1 ATOM 4708 O O . PRO A 1 595 ? -12.579 -4.029 26.771 1.00 17.57 ? 595 PRO A O 1 ATOM 4709 C CB . PRO A 1 595 ? -13.691 -5.424 29.600 1.00 15.57 ? 595 PRO A CB 1 ATOM 4710 C CG . PRO A 1 595 ? -14.272 -6.655 30.182 1.00 14.64 ? 595 PRO A CG 1 ATOM 4711 C CD . PRO A 1 595 ? -14.532 -7.629 29.077 1.00 15.28 ? 595 PRO A CD 1 ATOM 4712 N N . PHE A 1 596 ? -12.021 -6.203 26.894 1.00 16.71 ? 596 PHE A N 1 ATOM 4713 C CA . PHE A 1 596 ? -10.986 -6.164 25.844 1.00 16.20 ? 596 PHE A CA 1 ATOM 4714 C C . PHE A 1 596 ? -11.468 -7.019 24.699 1.00 15.76 ? 596 PHE A C 1 ATOM 4715 O O . PHE A 1 596 ? -11.691 -8.216 24.860 1.00 15.92 ? 596 PHE A O 1 ATOM 4716 C CB . PHE A 1 596 ? -9.639 -6.726 26.332 1.00 15.59 ? 596 PHE A CB 1 ATOM 4717 C CG . PHE A 1 596 ? -8.613 -6.851 25.248 1.00 15.68 ? 596 PHE A CG 1 ATOM 4718 C CD1 . PHE A 1 596 ? -8.218 -5.729 24.522 1.00 14.75 ? 596 PHE A CD1 1 ATOM 4719 C CD2 . PHE A 1 596 ? -8.059 -8.080 24.922 1.00 15.13 ? 596 PHE A CD2 1 ATOM 4720 C CE1 . PHE A 1 596 ? -7.266 -5.834 23.511 1.00 15.08 ? 596 PHE A CE1 1 ATOM 4721 C CE2 . PHE A 1 596 ? -7.080 -8.180 23.908 1.00 15.21 ? 596 PHE A CE2 1 ATOM 4722 C CZ . PHE A 1 596 ? -6.701 -7.046 23.202 1.00 11.18 ? 596 PHE A CZ 1 ATOM 4723 N N . SER A 1 597 ? -11.638 -6.403 23.539 1.00 15.85 ? 597 SER A N 1 ATOM 4724 C CA . SER A 1 597 ? -12.352 -7.042 22.437 1.00 16.69 ? 597 SER A CA 1 ATOM 4725 C C . SER A 1 597 ? -11.436 -7.170 21.232 1.00 15.70 ? 597 SER A C 1 ATOM 4726 O O . SER A 1 597 ? -11.228 -6.220 20.516 1.00 15.64 ? 597 SER A O 1 ATOM 4727 C CB . SER A 1 597 ? -13.598 -6.201 22.094 1.00 16.36 ? 597 SER A CB 1 ATOM 4728 O OG . SER A 1 597 ? -14.322 -6.757 21.026 1.00 16.73 ? 597 SER A OG 1 ATOM 4729 N N . ARG A 1 598 ? -10.880 -8.352 21.022 1.00 16.23 ? 598 ARG A N 1 ATOM 4730 C CA . ARG A 1 598 ? -9.934 -8.558 19.936 1.00 15.76 ? 598 ARG A CA 1 ATOM 4731 C C . ARG A 1 598 ? -10.200 -9.883 19.233 1.00 15.74 ? 598 ARG A C 1 ATOM 4732 O O . ARG A 1 598 ? -10.265 -10.935 19.868 1.00 15.79 ? 598 ARG A O 1 ATOM 4733 C CB . ARG A 1 598 ? -8.470 -8.463 20.448 1.00 15.35 ? 598 ARG A CB 1 ATOM 4734 C CG . ARG A 1 598 ? -7.452 -8.792 19.367 1.00 14.26 ? 598 ARG A CG 1 ATOM 4735 C CD . ARG A 1 598 ? -5.998 -8.622 19.799 1.00 16.27 ? 598 ARG A CD 1 ATOM 4736 N NE . ARG A 1 598 ? -5.574 -9.806 20.526 1.00 19.21 ? 598 ARG A NE 1 ATOM 4737 C CZ . ARG A 1 598 ? -4.315 -10.170 20.723 1.00 21.00 ? 598 ARG A CZ 1 ATOM 4738 N NH1 . ARG A 1 598 ? -3.310 -9.433 20.237 1.00 18.73 ? 598 ARG A NH1 1 ATOM 4739 N NH2 . ARG A 1 598 ? -4.081 -11.286 21.413 1.00 21.37 ? 598 ARG A NH2 1 ATOM 4740 N N . ASN A 1 599 ? -10.421 -9.819 17.920 1.00 15.93 ? 599 ASN A N 1 ATOM 4741 C CA . ASN A 1 599 ? -10.451 -11.004 17.067 1.00 15.89 ? 599 ASN A CA 1 ATOM 4742 C C . ASN A 1 599 ? -8.984 -11.277 16.684 1.00 16.01 ? 599 ASN A C 1 ATOM 4743 O O . ASN A 1 599 ? -8.380 -10.483 15.972 1.00 16.26 ? 599 ASN A O 1 ATOM 4744 C CB . ASN A 1 599 ? -11.338 -10.745 15.829 1.00 15.35 ? 599 ASN A CB 1 ATOM 4745 C CG . ASN A 1 599 ? -11.450 -11.947 14.866 1.00 16.20 ? 599 ASN A CG 1 ATOM 4746 O OD1 . ASN A 1 599 ? -10.458 -12.575 14.482 1.00 17.85 ? 599 ASN A OD1 1 ATOM 4747 N ND2 . ASN A 1 599 ? -12.671 -12.206 14.399 1.00 15.60 ? 599 ASN A ND2 1 ATOM 4748 N N . HIS A 1 600 ? -8.426 -12.385 17.171 1.00 16.47 ? 600 HIS A N 1 ATOM 4749 C CA . HIS A 1 600 ? -7.055 -12.798 16.837 1.00 16.01 ? 600 HIS A CA 1 ATOM 4750 C C . HIS A 1 600 ? -7.042 -14.273 16.378 1.00 16.94 ? 600 HIS A C 1 ATOM 4751 O O . HIS A 1 600 ? -7.899 -15.048 16.765 1.00 16.96 ? 600 HIS A O 1 ATOM 4752 C CB . HIS A 1 600 ? -6.118 -12.513 18.015 1.00 16.40 ? 600 HIS A CB 1 ATOM 4753 C CG . HIS A 1 600 ? -4.684 -12.911 17.795 1.00 15.39 ? 600 HIS A CG 1 ATOM 4754 N ND1 . HIS A 1 600 ? -3.919 -12.418 16.768 1.00 17.63 ? 600 HIS A ND1 1 ATOM 4755 C CD2 . HIS A 1 600 ? -3.863 -13.709 18.513 1.00 16.64 ? 600 HIS A CD2 1 ATOM 4756 C CE1 . HIS A 1 600 ? -2.695 -12.920 16.836 1.00 18.00 ? 600 HIS A CE1 1 ATOM 4757 N NE2 . HIS A 1 600 ? -2.636 -13.715 17.884 1.00 16.18 ? 600 HIS A NE2 1 ATOM 4758 N N . ASN A 1 601 ? -6.069 -14.652 15.546 1.00 16.90 ? 601 ASN A N 1 ATOM 4759 C CA . ASN A 1 601 ? -6.065 -15.935 14.850 1.00 17.55 ? 601 ASN A CA 1 ATOM 4760 C C . ASN A 1 601 ? -4.617 -16.444 14.829 1.00 18.06 ? 601 ASN A C 1 ATOM 4761 O O . ASN A 1 601 ? -3.691 -15.653 14.682 1.00 17.36 ? 601 ASN A O 1 ATOM 4762 C CB . ASN A 1 601 ? -6.544 -15.737 13.399 1.00 16.78 ? 601 ASN A CB 1 ATOM 4763 C CG . ASN A 1 601 ? -6.939 -17.047 12.686 1.00 16.09 ? 601 ASN A CG 1 ATOM 4764 O OD1 . ASN A 1 601 ? -7.081 -18.096 13.292 1.00 17.50 ? 601 ASN A OD1 1 ATOM 4765 N ND2 . ASN A 1 601 ? -7.134 -16.961 11.377 1.00 13.87 ? 601 ASN A ND2 1 ATOM 4766 N N . GLY A 1 602 ? -4.438 -17.757 14.937 1.00 18.93 ? 602 GLY A N 1 ATOM 4767 C CA . GLY A 1 602 ? -3.094 -18.351 14.894 1.00 19.72 ? 602 GLY A CA 1 ATOM 4768 C C . GLY A 1 602 ? -2.574 -18.521 13.478 1.00 20.96 ? 602 GLY A C 1 ATOM 4769 O O . GLY A 1 602 ? -3.263 -18.213 12.502 1.00 20.69 ? 602 GLY A O 1 ATOM 4770 N N . GLN A 1 603 ? -1.351 -19.029 13.378 1.00 21.88 ? 603 GLN A N 1 ATOM 4771 C CA . GLN A 1 603 ? -0.625 -19.128 12.125 1.00 23.46 ? 603 GLN A CA 1 ATOM 4772 C C . GLN A 1 603 ? -1.238 -20.177 11.208 1.00 24.03 ? 603 GLN A C 1 ATOM 4773 O O . GLN A 1 603 ? -1.550 -21.295 11.643 1.00 25.49 ? 603 GLN A O 1 ATOM 4774 C CB . GLN A 1 603 ? 0.831 -19.495 12.446 1.00 23.62 ? 603 GLN A CB 1 ATOM 4775 C CG . GLN A 1 603 ? 1.817 -19.372 11.302 1.00 25.62 ? 603 GLN A CG 1 ATOM 4776 C CD . GLN A 1 603 ? 3.243 -19.811 11.718 1.00 25.67 ? 603 GLN A CD 1 ATOM 4777 O OE1 . GLN A 1 603 ? 3.422 -20.616 12.638 1.00 28.82 ? 603 GLN A OE1 1 ATOM 4778 N NE2 . GLN A 1 603 ? 4.244 -19.282 11.038 1.00 31.23 ? 603 GLN A NE2 1 ATOM 4779 N N . GLY A 1 604 ? -1.438 -19.809 9.946 1.00 23.65 ? 604 GLY A N 1 ATOM 4780 C CA . GLY A 1 604 ? -1.812 -20.775 8.938 1.00 24.47 ? 604 GLY A CA 1 ATOM 4781 C C . GLY A 1 604 ? -3.297 -21.086 8.842 1.00 24.94 ? 604 GLY A C 1 ATOM 4782 O O . GLY A 1 604 ? -3.722 -21.680 7.856 1.00 25.23 ? 604 GLY A O 1 ATOM 4783 N N . TYR A 1 605 ? -4.097 -20.703 9.842 1.00 24.48 ? 605 TYR A N 1 ATOM 4784 C CA . TYR A 1 605 ? -5.524 -21.073 9.825 1.00 24.33 ? 605 TYR A CA 1 ATOM 4785 C C . TYR A 1 605 ? -6.326 -20.162 8.903 1.00 24.00 ? 605 TYR A C 1 ATOM 4786 O O . TYR A 1 605 ? -5.850 -19.092 8.533 1.00 23.39 ? 605 TYR A O 1 ATOM 4787 C CB . TYR A 1 605 ? -6.127 -21.145 11.237 1.00 24.63 ? 605 TYR A CB 1 ATOM 4788 C CG . TYR A 1 605 ? -5.318 -22.010 12.198 1.00 24.84 ? 605 TYR A CG 1 ATOM 4789 C CD1 . TYR A 1 605 ? -5.232 -23.397 12.035 1.00 23.28 ? 605 TYR A CD1 1 ATOM 4790 C CD2 . TYR A 1 605 ? -4.658 -21.436 13.265 1.00 24.32 ? 605 TYR A CD2 1 ATOM 4791 C CE1 . TYR A 1 605 ? -4.491 -24.180 12.924 1.00 26.86 ? 605 TYR A CE1 1 ATOM 4792 C CE2 . TYR A 1 605 ? -3.898 -22.194 14.145 1.00 26.64 ? 605 TYR A CE2 1 ATOM 4793 C CZ . TYR A 1 605 ? -3.817 -23.558 13.979 1.00 27.04 ? 605 TYR A CZ 1 ATOM 4794 O OH . TYR A 1 605 ? -3.077 -24.274 14.891 1.00 26.27 ? 605 TYR A OH 1 ATOM 4795 N N . LYS A 1 606 ? -7.528 -20.599 8.511 1.00 23.74 ? 606 LYS A N 1 ATOM 4796 C CA . LYS A 1 606 ? -8.346 -19.822 7.576 1.00 24.74 ? 606 LYS A CA 1 ATOM 4797 C C . LYS A 1 606 ? -8.618 -18.442 8.195 1.00 23.51 ? 606 LYS A C 1 ATOM 4798 O O . LYS A 1 606 ? -8.562 -18.287 9.409 1.00 23.28 ? 606 LYS A O 1 ATOM 4799 C CB . LYS A 1 606 ? -9.643 -20.572 7.166 1.00 24.64 ? 606 LYS A CB 1 ATOM 4800 C CG . LYS A 1 606 ? -10.872 -20.308 8.010 1.00 28.20 ? 606 LYS A CG 1 ATOM 4801 C CD . LYS A 1 606 ? -12.147 -21.042 7.478 1.00 27.91 ? 606 LYS A CD 1 ATOM 4802 C CE . LYS A 1 606 ? -13.444 -20.323 7.901 1.00 33.25 ? 606 LYS A CE 1 ATOM 4803 N NZ . LYS A 1 606 ? -14.725 -21.044 7.494 1.00 32.68 ? 606 LYS A NZ 1 ATOM 4804 N N . ASP A 1 607 ? -8.848 -17.439 7.358 1.00 22.99 ? 607 ASP A N 1 ATOM 4805 C CA . ASP A 1 607 ? -9.137 -16.082 7.824 1.00 22.43 ? 607 ASP A CA 1 ATOM 4806 C C . ASP A 1 607 ? -10.385 -16.078 8.708 1.00 21.22 ? 607 ASP A C 1 ATOM 4807 O O . ASP A 1 607 ? -11.360 -16.808 8.431 1.00 20.20 ? 607 ASP A O 1 ATOM 4808 C CB . ASP A 1 607 ? -9.351 -15.139 6.628 1.00 22.86 ? 607 ASP A CB 1 ATOM 4809 C CG . ASP A 1 607 ? -8.078 -14.862 5.863 1.00 26.46 ? 607 ASP A CG 1 ATOM 4810 O OD1 . ASP A 1 607 ? -6.974 -15.102 6.416 1.00 28.88 ? 607 ASP A OD1 1 ATOM 4811 O OD2 . ASP A 1 607 ? -8.183 -14.405 4.707 1.00 29.62 ? 607 ASP A OD2 1 ATOM 4812 N N . GLN A 1 608 ? -10.345 -15.264 9.769 1.00 20.46 ? 608 GLN A N 1 ATOM 4813 C CA . GLN A 1 608 ? -11.492 -15.129 10.678 1.00 19.66 ? 608 GLN A CA 1 ATOM 4814 C C . GLN A 1 608 ? -11.846 -13.705 11.053 1.00 19.50 ? 608 GLN A C 1 ATOM 4815 O O . GLN A 1 608 ? -12.706 -13.498 11.917 1.00 19.97 ? 608 GLN A O 1 ATOM 4816 C CB . GLN A 1 608 ? -11.360 -16.030 11.925 1.00 19.88 ? 608 GLN A CB 1 ATOM 4817 C CG . GLN A 1 608 ? -10.214 -15.714 12.865 1.00 18.92 ? 608 GLN A CG 1 ATOM 4818 C CD . GLN A 1 608 ? -10.033 -16.808 13.907 1.00 17.88 ? 608 GLN A CD 1 ATOM 4819 O OE1 . GLN A 1 608 ? -10.173 -18.002 13.608 1.00 17.82 ? 608 GLN A OE1 1 ATOM 4820 N NE2 . GLN A 1 608 ? -9.740 -16.410 15.128 1.00 15.22 ? 608 GLN A NE2 1 ATOM 4821 N N . ASP A 1 609 ? -11.229 -12.743 10.362 1.00 18.06 ? 609 ASP A N 1 ATOM 4822 C CA . ASP A 1 609 ? -11.593 -11.356 10.464 1.00 18.14 ? 609 ASP A CA 1 ATOM 4823 C C . ASP A 1 609 ? -13.030 -11.221 9.964 1.00 18.65 ? 609 ASP A C 1 ATOM 4824 O O . ASP A 1 609 ? -13.428 -11.928 9.031 1.00 18.43 ? 609 ASP A O 1 ATOM 4825 C CB . ASP A 1 609 ? -10.636 -10.457 9.694 1.00 18.02 ? 609 ASP A CB 1 ATOM 4826 C CG . ASP A 1 609 ? -10.521 -10.813 8.233 1.00 19.33 ? 609 ASP A CG 1 ATOM 4827 O OD1 . ASP A 1 609 ? -9.902 -11.854 7.889 1.00 18.36 ? 609 ASP A OD1 1 ATOM 4828 O OD2 . ASP A 1 609 ? -11.008 -10.013 7.422 1.00 21.06 ? 609 ASP A OD2 1 ATOM 4829 N N . PRO A 1 610 ? -13.824 -10.382 10.627 1.00 18.04 ? 610 PRO A N 1 ATOM 4830 C CA . PRO A 1 610 ? -15.254 -10.310 10.294 1.00 19.47 ? 610 PRO A CA 1 ATOM 4831 C C . PRO A 1 610 ? -15.592 -10.206 8.786 1.00 19.61 ? 610 PRO A C 1 ATOM 4832 O O . PRO A 1 610 ? -16.433 -10.949 8.319 1.00 19.85 ? 610 PRO A O 1 ATOM 4833 C CB . PRO A 1 610 ? -15.750 -9.111 11.109 1.00 18.73 ? 610 PRO A CB 1 ATOM 4834 C CG . PRO A 1 610 ? -14.771 -9.007 12.255 1.00 18.81 ? 610 PRO A CG 1 ATOM 4835 C CD . PRO A 1 610 ? -13.464 -9.535 11.783 1.00 19.47 ? 610 PRO A CD 1 ATOM 4836 N N . ALA A 1 611 ? -14.922 -9.332 8.033 1.00 20.64 ? 611 ALA A N 1 ATOM 4837 C CA . ALA A 1 611 ? -15.249 -9.127 6.612 1.00 21.53 ? 611 ALA A CA 1 ATOM 4838 C C . ALA A 1 611 ? -14.801 -10.266 5.684 1.00 22.42 ? 611 ALA A C 1 ATOM 4839 O O . ALA A 1 611 ? -15.108 -10.231 4.491 1.00 22.85 ? 611 ALA A O 1 ATOM 4840 C CB . ALA A 1 611 ? -14.688 -7.781 6.109 1.00 20.50 ? 611 ALA A CB 1 ATOM 4841 N N . SER A 1 612 ? -14.067 -11.258 6.215 1.00 23.49 ? 612 SER A N 1 ATOM 4842 C CA . SER A 1 612 ? -13.599 -12.395 5.395 1.00 24.50 ? 612 SER A CA 1 ATOM 4843 C C . SER A 1 612 ? -14.722 -13.401 5.139 1.00 25.13 ? 612 SER A C 1 ATOM 4844 O O . SER A 1 612 ? -14.601 -14.259 4.251 1.00 24.77 ? 612 SER A O 1 ATOM 4845 C CB . SER A 1 612 ? -12.356 -13.080 5.990 1.00 24.59 ? 612 SER A CB 1 ATOM 4846 O OG . SER A 1 612 ? -12.633 -13.710 7.234 1.00 25.77 ? 612 SER A OG 1 ATOM 4847 N N . PHE A 1 613 ? -15.814 -13.278 5.909 1.00 24.95 ? 613 PHE A N 1 ATOM 4848 C CA . PHE A 1 613 ? -16.966 -14.160 5.775 1.00 24.62 ? 613 PHE A CA 1 ATOM 4849 C C . PHE A 1 613 ? -17.947 -13.691 4.710 1.00 25.11 ? 613 PHE A C 1 ATOM 4850 O O . PHE A 1 613 ? -18.897 -14.403 4.389 1.00 26.08 ? 613 PHE A O 1 ATOM 4851 C CB . PHE A 1 613 ? -17.680 -14.327 7.120 1.00 24.64 ? 613 PHE A CB 1 ATOM 4852 C CG . PHE A 1 613 ? -16.881 -15.089 8.138 1.00 23.03 ? 613 PHE A CG 1 ATOM 4853 C CD1 . PHE A 1 613 ? -17.165 -16.414 8.393 1.00 22.17 ? 613 PHE A CD1 1 ATOM 4854 C CD2 . PHE A 1 613 ? -15.821 -14.471 8.833 1.00 23.20 ? 613 PHE A CD2 1 ATOM 4855 C CE1 . PHE A 1 613 ? -16.421 -17.135 9.331 1.00 23.50 ? 613 PHE A CE1 1 ATOM 4856 C CE2 . PHE A 1 613 ? -15.072 -15.171 9.773 1.00 21.07 ? 613 PHE A CE2 1 ATOM 4857 C CZ . PHE A 1 613 ? -15.361 -16.512 10.015 1.00 22.11 ? 613 PHE A CZ 1 ATOM 4858 N N . GLY A 1 614 ? -17.722 -12.490 4.176 1.00 25.26 ? 614 GLY A N 1 ATOM 4859 C CA . GLY A 1 614 ? -18.475 -11.988 3.047 1.00 24.75 ? 614 GLY A CA 1 ATOM 4860 C C . GLY A 1 614 ? -19.039 -10.619 3.325 1.00 24.67 ? 614 GLY A C 1 ATOM 4861 O O . GLY A 1 614 ? -19.557 -10.367 4.408 1.00 23.74 ? 614 GLY A O 1 ATOM 4862 N N . ALA A 1 615 ? -18.933 -9.746 2.332 1.00 25.26 ? 615 ALA A N 1 ATOM 4863 C CA . ALA A 1 615 ? -19.370 -8.370 2.421 1.00 26.35 ? 615 ALA A CA 1 ATOM 4864 C C . ALA A 1 615 ? -20.828 -8.294 2.826 1.00 26.86 ? 615 ALA A C 1 ATOM 4865 O O . ALA A 1 615 ? -21.251 -7.301 3.406 1.00 28.04 ? 615 ALA A O 1 ATOM 4866 C CB . ALA A 1 615 ? -19.186 -7.688 1.081 1.00 27.15 ? 615 ALA A CB 1 ATOM 4867 N N . ASP A 1 616 ? -21.579 -9.355 2.536 1.00 27.33 ? 616 ASP A N 1 ATOM 4868 C CA . ASP A 1 616 ? -23.011 -9.414 2.838 1.00 27.72 ? 616 ASP A CA 1 ATOM 4869 C C . ASP A 1 616 ? -23.399 -10.530 3.803 1.00 26.30 ? 616 ASP A C 1 ATOM 4870 O O . ASP A 1 616 ? -24.587 -10.796 3.981 1.00 26.14 ? 616 ASP A O 1 ATOM 4871 C CB . ASP A 1 616 ? -23.831 -9.530 1.545 1.00 28.07 ? 616 ASP A CB 1 ATOM 4872 C CG . ASP A 1 616 ? -23.854 -8.231 0.753 1.00 32.44 ? 616 ASP A CG 1 ATOM 4873 O OD1 . ASP A 1 616 ? -23.660 -8.294 -0.487 1.00 36.58 ? 616 ASP A OD1 1 ATOM 4874 O OD2 . ASP A 1 616 ? -24.056 -7.143 1.364 1.00 35.83 ? 616 ASP A OD2 1 ATOM 4875 N N . SER A 1 617 ? -22.409 -11.155 4.444 1.00 24.47 ? 617 SER A N 1 ATOM 4876 C CA . SER A 1 617 ? -22.663 -12.320 5.305 1.00 22.83 ? 617 SER A CA 1 ATOM 4877 C C . SER A 1 617 ? -23.444 -11.990 6.586 1.00 21.93 ? 617 SER A C 1 ATOM 4878 O O . SER A 1 617 ? -23.353 -10.884 7.086 1.00 21.66 ? 617 SER A O 1 ATOM 4879 C CB . SER A 1 617 ? -21.344 -12.965 5.695 1.00 22.52 ? 617 SER A CB 1 ATOM 4880 O OG . SER A 1 617 ? -20.568 -12.072 6.479 1.00 21.40 ? 617 SER A OG 1 ATOM 4881 N N . LEU A 1 618 ? -24.174 -12.968 7.138 1.00 22.60 ? 618 LEU A N 1 ATOM 4882 C CA . LEU A 1 618 ? -24.883 -12.776 8.415 1.00 22.23 ? 618 LEU A CA 1 ATOM 4883 C C . LEU A 1 618 ? -23.897 -12.436 9.519 1.00 21.79 ? 618 LEU A C 1 ATOM 4884 O O . LEU A 1 618 ? -24.206 -11.663 10.421 1.00 21.43 ? 618 LEU A O 1 ATOM 4885 C CB . LEU A 1 618 ? -25.713 -14.003 8.823 1.00 21.98 ? 618 LEU A CB 1 ATOM 4886 C CG . LEU A 1 618 ? -26.511 -13.838 10.121 1.00 22.67 ? 618 LEU A CG 1 ATOM 4887 C CD1 . LEU A 1 618 ? -27.533 -12.682 10.021 1.00 23.27 ? 618 LEU A CD1 1 ATOM 4888 C CD2 . LEU A 1 618 ? -27.220 -15.122 10.471 1.00 24.75 ? 618 LEU A CD2 1 ATOM 4889 N N . LEU A 1 619 ? -22.698 -13.003 9.429 1.00 21.50 ? 619 LEU A N 1 ATOM 4890 C CA . LEU A 1 619 ? -21.683 -12.777 10.452 1.00 20.56 ? 619 LEU A CA 1 ATOM 4891 C C . LEU A 1 619 ? -21.154 -11.359 10.460 1.00 20.46 ? 619 LEU A C 1 ATOM 4892 O O . LEU A 1 619 ? -20.983 -10.771 11.521 1.00 19.41 ? 619 LEU A O 1 ATOM 4893 C CB . LEU A 1 619 ? -20.532 -13.776 10.321 1.00 20.25 ? 619 LEU A CB 1 ATOM 4894 C CG . LEU A 1 619 ? -19.416 -13.663 11.371 1.00 20.62 ? 619 LEU A CG 1 ATOM 4895 C CD1 . LEU A 1 619 ? -18.730 -14.987 11.554 1.00 17.56 ? 619 LEU A CD1 1 ATOM 4896 C CD2 . LEU A 1 619 ? -18.380 -12.564 11.033 1.00 20.05 ? 619 LEU A CD2 1 ATOM 4897 N N . LEU A 1 620 ? -20.862 -10.808 9.281 1.00 20.98 ? 620 LEU A N 1 ATOM 4898 C CA . LEU A 1 620 ? -20.344 -9.446 9.195 1.00 20.61 ? 620 LEU A CA 1 ATOM 4899 C C . LEU A 1 620 ? -21.395 -8.458 9.641 1.00 20.97 ? 620 LEU A C 1 ATOM 4900 O O . LEU A 1 620 ? -21.109 -7.540 10.416 1.00 21.27 ? 620 LEU A O 1 ATOM 4901 C CB . LEU A 1 620 ? -19.904 -9.108 7.759 1.00 20.92 ? 620 LEU A CB 1 ATOM 4902 C CG . LEU A 1 620 ? -19.410 -7.675 7.564 1.00 20.86 ? 620 LEU A CG 1 ATOM 4903 C CD1 . LEU A 1 620 ? -18.145 -7.418 8.392 1.00 20.79 ? 620 LEU A CD1 1 ATOM 4904 C CD2 . LEU A 1 620 ? -19.187 -7.347 6.083 1.00 21.13 ? 620 LEU A CD2 1 ATOM 4905 N N . ASN A 1 621 ? -22.599 -8.637 9.114 1.00 20.75 ? 621 ASN A N 1 ATOM 4906 C CA . ASN A 1 621 ? -23.769 -7.842 9.489 1.00 22.14 ? 621 ASN A CA 1 ATOM 4907 C C . ASN A 1 621 ? -24.040 -7.839 10.990 1.00 21.02 ? 621 ASN A C 1 ATOM 4908 O O . ASN A 1 621 ? -24.141 -6.789 11.586 1.00 21.68 ? 621 ASN A O 1 ATOM 4909 C CB . ASN A 1 621 ? -25.010 -8.307 8.701 1.00 22.16 ? 621 ASN A CB 1 ATOM 4910 C CG . ASN A 1 621 ? -24.983 -7.853 7.233 1.00 28.59 ? 621 ASN A CG 1 ATOM 4911 O OD1 . ASN A 1 621 ? -24.060 -7.144 6.781 1.00 31.59 ? 621 ASN A OD1 1 ATOM 4912 N ND2 . ASN A 1 621 ? -26.014 -8.248 6.479 1.00 33.39 ? 621 ASN A ND2 1 ATOM 4913 N N . SER A 1 622 ? -24.130 -9.015 11.598 1.00 21.22 ? 622 SER A N 1 ATOM 4914 C CA . SER A 1 622 ? -24.283 -9.144 13.063 1.00 20.20 ? 622 SER A CA 1 ATOM 4915 C C . SER A 1 622 ? -23.084 -8.552 13.834 1.00 19.98 ? 622 SER A C 1 ATOM 4916 O O . SER A 1 622 ? -23.257 -7.831 14.822 1.00 19.75 ? 622 SER A O 1 ATOM 4917 C CB . SER A 1 622 ? -24.449 -10.606 13.417 1.00 20.29 ? 622 SER A CB 1 ATOM 4918 O OG . SER A 1 622 ? -24.737 -10.762 14.794 1.00 23.46 ? 622 SER A OG 1 ATOM 4919 N N . SER A 1 623 ? -21.868 -8.831 13.370 1.00 18.13 ? 623 SER A N 1 ATOM 4920 C CA . SER A 1 623 ? -20.697 -8.269 14.022 1.00 17.84 ? 623 SER A CA 1 ATOM 4921 C C . SER A 1 623 ? -20.722 -6.772 14.060 1.00 17.08 ? 623 SER A C 1 ATOM 4922 O O . SER A 1 623 ? -20.468 -6.177 15.094 1.00 17.08 ? 623 SER A O 1 ATOM 4923 C CB . SER A 1 623 ? -19.426 -8.729 13.323 1.00 17.32 ? 623 SER A CB 1 ATOM 4924 O OG . SER A 1 623 ? -19.396 -10.122 13.420 1.00 18.15 ? 623 SER A OG 1 ATOM 4925 N N . ARG A 1 624 ? -21.015 -6.167 12.913 1.00 16.91 ? 624 ARG A N 1 ATOM 4926 C CA . ARG A 1 624 ? -21.088 -4.739 12.801 1.00 16.29 ? 624 ARG A CA 1 ATOM 4927 C C . ARG A 1 624 ? -22.202 -4.211 13.680 1.00 15.51 ? 624 ARG A C 1 ATOM 4928 O O . ARG A 1 624 ? -22.003 -3.243 14.371 1.00 14.68 ? 624 ARG A O 1 ATOM 4929 C CB . ARG A 1 624 ? -21.284 -4.304 11.321 1.00 16.75 ? 624 ARG A CB 1 ATOM 4930 C CG . ARG A 1 624 ? -21.271 -2.796 11.072 1.00 16.13 ? 624 ARG A CG 1 ATOM 4931 C CD . ARG A 1 624 ? -21.504 -2.437 9.555 1.00 18.58 ? 624 ARG A CD 1 ATOM 4932 N NE . ARG A 1 624 ? -22.543 -3.289 8.990 1.00 22.04 ? 624 ARG A NE 1 ATOM 4933 C CZ . ARG A 1 624 ? -22.433 -4.006 7.880 1.00 24.00 ? 624 ARG A CZ 1 ATOM 4934 N NH1 . ARG A 1 624 ? -21.334 -3.958 7.134 1.00 24.07 ? 624 ARG A NH1 1 ATOM 4935 N NH2 . ARG A 1 624 ? -23.466 -4.747 7.496 1.00 24.78 ? 624 ARG A NH2 1 ATOM 4936 N N . HIS A 1 625 ? -23.369 -4.857 13.650 1.00 15.51 ? 625 HIS A N 1 ATOM 4937 C CA . HIS A 1 625 ? -24.499 -4.450 14.504 1.00 15.37 ? 625 HIS A CA 1 ATOM 4938 C C . HIS A 1 625 ? -24.139 -4.358 15.996 1.00 14.41 ? 625 HIS A C 1 ATOM 4939 O O . HIS A 1 625 ? -24.313 -3.331 16.614 1.00 14.18 ? 625 HIS A O 1 ATOM 4940 C CB . HIS A 1 625 ? -25.682 -5.411 14.280 1.00 15.38 ? 625 HIS A CB 1 ATOM 4941 C CG . HIS A 1 625 ? -26.934 -5.003 14.996 1.00 18.91 ? 625 HIS A CG 1 ATOM 4942 N ND1 . HIS A 1 625 ? -27.480 -5.740 16.019 1.00 21.09 ? 625 HIS A ND1 1 ATOM 4943 C CD2 . HIS A 1 625 ? -27.747 -3.935 14.830 1.00 22.88 ? 625 HIS A CD2 1 ATOM 4944 C CE1 . HIS A 1 625 ? -28.571 -5.142 16.460 1.00 23.68 ? 625 HIS A CE1 1 ATOM 4945 N NE2 . HIS A 1 625 ? -28.757 -4.042 15.753 1.00 24.48 ? 625 HIS A NE2 1 ATOM 4946 N N . TYR A 1 626 ? -23.604 -5.433 16.565 1.00 14.80 ? 626 TYR A N 1 ATOM 4947 C CA . TYR A 1 626 ? -23.316 -5.468 17.989 1.00 14.73 ? 626 TYR A CA 1 ATOM 4948 C C . TYR A 1 626 ? -22.072 -4.697 18.359 1.00 14.49 ? 626 TYR A C 1 ATOM 4949 O O . TYR A 1 626 ? -21.973 -4.178 19.474 1.00 13.90 ? 626 TYR A O 1 ATOM 4950 C CB . TYR A 1 626 ? -23.261 -6.918 18.496 1.00 15.52 ? 626 TYR A CB 1 ATOM 4951 C CG . TYR A 1 626 ? -24.650 -7.477 18.577 1.00 15.60 ? 626 TYR A CG 1 ATOM 4952 C CD1 . TYR A 1 626 ? -25.080 -8.451 17.693 1.00 16.91 ? 626 TYR A CD1 1 ATOM 4953 C CD2 . TYR A 1 626 ? -25.563 -6.960 19.499 1.00 15.04 ? 626 TYR A CD2 1 ATOM 4954 C CE1 . TYR A 1 626 ? -26.395 -8.938 17.761 1.00 18.35 ? 626 TYR A CE1 1 ATOM 4955 C CE2 . TYR A 1 626 ? -26.867 -7.438 19.569 1.00 16.09 ? 626 TYR A CE2 1 ATOM 4956 C CZ . TYR A 1 626 ? -27.262 -8.422 18.706 1.00 15.91 ? 626 TYR A CZ 1 ATOM 4957 O OH . TYR A 1 626 ? -28.555 -8.882 18.771 1.00 19.17 ? 626 TYR A OH 1 ATOM 4958 N N . LEU A 1 627 ? -21.155 -4.565 17.413 1.00 14.31 ? 627 LEU A N 1 ATOM 4959 C CA . LEU A 1 627 ? -20.028 -3.666 17.651 1.00 15.34 ? 627 LEU A CA 1 ATOM 4960 C C . LEU A 1 627 ? -20.512 -2.233 17.641 1.00 15.93 ? 627 LEU A C 1 ATOM 4961 O O . LEU A 1 627 ? -19.952 -1.401 18.342 1.00 16.48 ? 627 LEU A O 1 ATOM 4962 C CB . LEU A 1 627 ? -18.915 -3.888 16.637 1.00 14.63 ? 627 LEU A CB 1 ATOM 4963 C CG . LEU A 1 627 ? -17.954 -5.041 16.977 1.00 18.74 ? 627 LEU A CG 1 ATOM 4964 C CD1 . LEU A 1 627 ? -17.077 -5.329 15.784 1.00 19.95 ? 627 LEU A CD1 1 ATOM 4965 C CD2 . LEU A 1 627 ? -17.079 -4.694 18.197 1.00 19.27 ? 627 LEU A CD2 1 ATOM 4966 N N . ASN A 1 628 ? -21.557 -1.927 16.855 1.00 15.24 ? 628 ASN A N 1 ATOM 4967 C CA . ASN A 1 628 ? -22.052 -0.550 16.860 1.00 15.67 ? 628 ASN A CA 1 ATOM 4968 C C . ASN A 1 628 ? -22.747 -0.248 18.165 1.00 14.38 ? 628 ASN A C 1 ATOM 4969 O O . ASN A 1 628 ? -22.714 0.881 18.659 1.00 14.16 ? 628 ASN A O 1 ATOM 4970 C CB . ASN A 1 628 ? -22.952 -0.253 15.657 1.00 15.87 ? 628 ASN A CB 1 ATOM 4971 C CG . ASN A 1 628 ? -22.179 0.297 14.494 1.00 18.18 ? 628 ASN A CG 1 ATOM 4972 O OD1 . ASN A 1 628 ? -22.410 -0.076 13.326 1.00 21.93 ? 628 ASN A OD1 1 ATOM 4973 N ND2 . ASN A 1 628 ? -21.243 1.184 14.795 1.00 18.19 ? 628 ASN A ND2 1 ATOM 4974 N N . ILE A 1 629 ? -23.332 -1.288 18.745 1.00 14.35 ? 629 ILE A N 1 ATOM 4975 C CA . ILE A 1 629 ? -23.921 -1.203 20.096 1.00 14.30 ? 629 ILE A CA 1 ATOM 4976 C C . ILE A 1 629 ? -22.861 -1.042 21.168 1.00 13.78 ? 629 ILE A C 1 ATOM 4977 O O . ILE A 1 629 ? -22.992 -0.191 22.020 1.00 14.78 ? 629 ILE A O 1 ATOM 4978 C CB . ILE A 1 629 ? -24.814 -2.395 20.399 1.00 14.57 ? 629 ILE A CB 1 ATOM 4979 C CG1 . ILE A 1 629 ? -26.086 -2.307 19.535 1.00 13.78 ? 629 ILE A CG1 1 ATOM 4980 C CG2 . ILE A 1 629 ? -25.165 -2.418 21.935 1.00 15.88 ? 629 ILE A CG2 1 ATOM 4981 C CD1 . ILE A 1 629 ? -26.832 -3.601 19.500 1.00 15.87 ? 629 ILE A CD1 1 ATOM 4982 N N . ARG A 1 630 ? -21.792 -1.836 21.119 1.00 13.86 ? 630 ARG A N 1 ATOM 4983 C CA . ARG A 1 630 ? -20.652 -1.606 22.021 1.00 13.40 ? 630 ARG A CA 1 ATOM 4984 C C . ARG A 1 630 ? -20.196 -0.160 21.962 1.00 13.82 ? 630 ARG A C 1 ATOM 4985 O O . ARG A 1 630 ? -20.009 0.493 23.012 1.00 12.64 ? 630 ARG A O 1 ATOM 4986 C CB . ARG A 1 630 ? -19.454 -2.520 21.654 1.00 13.28 ? 630 ARG A CB 1 ATOM 4987 C CG . ARG A 1 630 ? -18.162 -2.202 22.485 1.00 11.24 ? 630 ARG A CG 1 ATOM 4988 C CD . ARG A 1 630 ? -16.900 -2.838 21.873 1.00 14.19 ? 630 ARG A CD 1 ATOM 4989 N NE . ARG A 1 630 ? -15.751 -2.700 22.787 1.00 12.27 ? 630 ARG A NE 1 ATOM 4990 C CZ . ARG A 1 630 ? -15.475 -3.547 23.779 1.00 12.99 ? 630 ARG A CZ 1 ATOM 4991 N NH1 . ARG A 1 630 ? -16.240 -4.612 23.996 1.00 13.13 ? 630 ARG A NH1 1 ATOM 4992 N NH2 . ARG A 1 630 ? -14.439 -3.335 24.573 1.00 14.08 ? 630 ARG A NH2 1 ATOM 4993 N N . TYR A 1 631 ? -19.979 0.343 20.737 1.00 14.45 ? 631 TYR A N 1 ATOM 4994 C CA . TYR A 1 631 ? -19.459 1.727 20.554 1.00 14.40 ? 631 TYR A CA 1 ATOM 4995 C C . TYR A 1 631 ? -20.446 2.793 21.063 1.00 14.25 ? 631 TYR A C 1 ATOM 4996 O O . TYR A 1 631 ? -20.067 3.797 21.666 1.00 14.01 ? 631 TYR A O 1 ATOM 4997 C CB . TYR A 1 631 ? -19.100 1.964 19.083 1.00 14.42 ? 631 TYR A CB 1 ATOM 4998 C CG . TYR A 1 631 ? -17.694 1.518 18.716 1.00 16.39 ? 631 TYR A CG 1 ATOM 4999 C CD1 . TYR A 1 631 ? -17.261 0.218 18.954 1.00 17.55 ? 631 TYR A CD1 1 ATOM 5000 C CD2 . TYR A 1 631 ? -16.785 2.423 18.133 1.00 19.13 ? 631 TYR A CD2 1 ATOM 5001 C CE1 . TYR A 1 631 ? -15.940 -0.196 18.617 1.00 17.40 ? 631 TYR A CE1 1 ATOM 5002 C CE2 . TYR A 1 631 ? -15.472 2.016 17.776 1.00 18.30 ? 631 TYR A CE2 1 ATOM 5003 C CZ . TYR A 1 631 ? -15.071 0.718 18.035 1.00 16.02 ? 631 TYR A CZ 1 ATOM 5004 O OH . TYR A 1 631 ? -13.820 0.316 17.681 1.00 14.86 ? 631 TYR A OH 1 ATOM 5005 N N . THR A 1 632 ? -21.727 2.566 20.824 1.00 13.84 ? 632 THR A N 1 ATOM 5006 C CA . THR A 1 632 ? -22.767 3.417 21.419 1.00 14.31 ? 632 THR A CA 1 ATOM 5007 C C . THR A 1 632 ? -22.628 3.507 22.934 1.00 14.54 ? 632 THR A C 1 ATOM 5008 O O . THR A 1 632 ? -22.832 4.558 23.509 1.00 15.53 ? 632 THR A O 1 ATOM 5009 C CB . THR A 1 632 ? -24.175 2.868 21.067 1.00 13.85 ? 632 THR A CB 1 ATOM 5010 O OG1 . THR A 1 632 ? -24.294 2.757 19.649 1.00 13.31 ? 632 THR A OG1 1 ATOM 5011 C CG2 . THR A 1 632 ? -25.271 3.808 21.559 1.00 14.93 ? 632 THR A CG2 1 ATOM 5012 N N . LEU A 1 633 ? -22.258 2.407 23.590 1.00 14.96 ? 633 LEU A N 1 ATOM 5013 C CA . LEU A 1 633 ? -22.269 2.358 25.052 1.00 15.90 ? 633 LEU A CA 1 ATOM 5014 C C . LEU A 1 633 ? -20.895 2.604 25.585 1.00 15.46 ? 633 LEU A C 1 ATOM 5015 O O . LEU A 1 633 ? -20.664 2.363 26.758 1.00 15.81 ? 633 LEU A O 1 ATOM 5016 C CB . LEU A 1 633 ? -22.795 0.991 25.581 1.00 15.31 ? 633 LEU A CB 1 ATOM 5017 C CG . LEU A 1 633 ? -24.277 0.688 25.347 1.00 18.17 ? 633 LEU A CG 1 ATOM 5018 C CD1 . LEU A 1 633 ? -24.536 -0.809 25.482 1.00 17.36 ? 633 LEU A CD1 1 ATOM 5019 C CD2 . LEU A 1 633 ? -25.172 1.490 26.307 1.00 19.58 ? 633 LEU A CD2 1 ATOM 5020 N N . LEU A 1 634 ? -19.975 3.078 24.744 1.00 15.40 ? 634 LEU A N 1 ATOM 5021 C CA . LEU A 1 634 ? -18.610 3.392 25.245 1.00 15.23 ? 634 LEU A CA 1 ATOM 5022 C C . LEU A 1 634 ? -18.534 4.450 26.346 1.00 14.60 ? 634 LEU A C 1 ATOM 5023 O O . LEU A 1 634 ? -17.720 4.332 27.223 1.00 13.44 ? 634 LEU A O 1 ATOM 5024 C CB . LEU A 1 634 ? -17.649 3.733 24.114 1.00 15.95 ? 634 LEU A CB 1 ATOM 5025 C CG . LEU A 1 634 ? -17.309 2.602 23.153 1.00 17.88 ? 634 LEU A CG 1 ATOM 5026 C CD1 . LEU A 1 634 ? -16.423 3.085 22.021 1.00 17.94 ? 634 LEU A CD1 1 ATOM 5027 C CD2 . LEU A 1 634 ? -16.719 1.398 23.853 1.00 19.84 ? 634 LEU A CD2 1 ATOM 5028 N N . PRO A 1 635 ? -19.363 5.526 26.302 1.00 14.24 ? 635 PRO A N 1 ATOM 5029 C CA . PRO A 1 635 ? -19.302 6.363 27.496 1.00 13.23 ? 635 PRO A CA 1 ATOM 5030 C C . PRO A 1 635 ? -19.674 5.665 28.817 1.00 12.89 ? 635 PRO A C 1 ATOM 5031 O O . PRO A 1 635 ? -19.107 5.972 29.845 1.00 12.82 ? 635 PRO A O 1 ATOM 5032 C CB . PRO A 1 635 ? -20.264 7.522 27.155 1.00 15.04 ? 635 PRO A CB 1 ATOM 5033 C CG . PRO A 1 635 ? -20.223 7.609 25.661 1.00 13.43 ? 635 PRO A CG 1 ATOM 5034 C CD . PRO A 1 635 ? -20.218 6.129 25.259 1.00 14.51 ? 635 PRO A CD 1 ATOM 5035 N N . TYR A 1 636 ? -20.662 4.772 28.784 1.00 13.20 ? 636 TYR A N 1 ATOM 5036 C CA . TYR A 1 636 ? -20.984 3.892 29.904 1.00 12.60 ? 636 TYR A CA 1 ATOM 5037 C C . TYR A 1 636 ? -19.792 2.975 30.271 1.00 12.28 ? 636 TYR A C 1 ATOM 5038 O O . TYR A 1 636 ? -19.422 2.916 31.403 1.00 11.89 ? 636 TYR A O 1 ATOM 5039 C CB . TYR A 1 636 ? -22.211 3.040 29.559 1.00 11.91 ? 636 TYR A CB 1 ATOM 5040 C CG . TYR A 1 636 ? -22.627 2.058 30.648 1.00 13.19 ? 636 TYR A CG 1 ATOM 5041 C CD1 . TYR A 1 636 ? -22.965 2.496 31.915 1.00 13.17 ? 636 TYR A CD1 1 ATOM 5042 C CD2 . TYR A 1 636 ? -22.727 0.702 30.382 1.00 10.46 ? 636 TYR A CD2 1 ATOM 5043 C CE1 . TYR A 1 636 ? -23.347 1.609 32.907 1.00 13.52 ? 636 TYR A CE1 1 ATOM 5044 C CE2 . TYR A 1 636 ? -23.118 -0.187 31.367 1.00 11.67 ? 636 TYR A CE2 1 ATOM 5045 C CZ . TYR A 1 636 ? -23.417 0.276 32.621 1.00 11.46 ? 636 TYR A CZ 1 ATOM 5046 O OH . TYR A 1 636 ? -23.791 -0.608 33.585 1.00 14.66 ? 636 TYR A OH 1 ATOM 5047 N N . LEU A 1 637 ? -19.251 2.229 29.318 1.00 12.79 ? 637 LEU A N 1 ATOM 5048 C CA . LEU A 1 637 ? -18.058 1.384 29.584 1.00 13.69 ? 637 LEU A CA 1 ATOM 5049 C C . LEU A 1 637 ? -16.898 2.171 30.153 1.00 14.22 ? 637 LEU A C 1 ATOM 5050 O O . LEU A 1 637 ? -16.219 1.725 31.095 1.00 15.04 ? 637 LEU A O 1 ATOM 5051 C CB . LEU A 1 637 ? -17.626 0.632 28.322 1.00 13.50 ? 637 LEU A CB 1 ATOM 5052 C CG . LEU A 1 637 ? -16.568 -0.466 28.483 1.00 13.34 ? 637 LEU A CG 1 ATOM 5053 C CD1 . LEU A 1 637 ? -17.172 -1.613 29.362 1.00 11.23 ? 637 LEU A CD1 1 ATOM 5054 C CD2 . LEU A 1 637 ? -16.221 -0.957 27.116 1.00 11.21 ? 637 LEU A CD2 1 ATOM 5055 N N . TYR A 1 638 ? -16.646 3.341 29.580 1.00 14.70 ? 638 TYR A N 1 ATOM 5056 C CA . TYR A 1 638 ? -15.519 4.168 30.015 1.00 14.67 ? 638 TYR A CA 1 ATOM 5057 C C . TYR A 1 638 ? -15.680 4.661 31.462 1.00 14.29 ? 638 TYR A C 1 ATOM 5058 O O . TYR A 1 638 ? -14.722 4.703 32.235 1.00 13.71 ? 638 TYR A O 1 ATOM 5059 C CB . TYR A 1 638 ? -15.362 5.370 29.064 1.00 15.10 ? 638 TYR A CB 1 ATOM 5060 C CG . TYR A 1 638 ? -14.077 6.164 29.246 1.00 13.11 ? 638 TYR A CG 1 ATOM 5061 C CD1 . TYR A 1 638 ? -12.827 5.542 29.136 1.00 14.70 ? 638 TYR A CD1 1 ATOM 5062 C CD2 . TYR A 1 638 ? -14.111 7.526 29.493 1.00 12.83 ? 638 TYR A CD2 1 ATOM 5063 C CE1 . TYR A 1 638 ? -11.629 6.254 29.288 1.00 15.10 ? 638 TYR A CE1 1 ATOM 5064 C CE2 . TYR A 1 638 ? -12.902 8.263 29.635 1.00 12.99 ? 638 TYR A CE2 1 ATOM 5065 C CZ . TYR A 1 638 ? -11.681 7.612 29.532 1.00 15.65 ? 638 TYR A CZ 1 ATOM 5066 O OH . TYR A 1 638 ? -10.503 8.346 29.654 1.00 14.68 ? 638 TYR A OH 1 ATOM 5067 N N . THR A 1 639 ? -16.908 5.031 31.826 1.00 13.90 ? 639 THR A N 1 ATOM 5068 C CA . THR A 1 639 ? -17.204 5.425 33.193 1.00 13.23 ? 639 THR A CA 1 ATOM 5069 C C . THR A 1 639 ? -16.975 4.253 34.169 1.00 12.71 ? 639 THR A C 1 ATOM 5070 O O . THR A 1 639 ? -16.481 4.462 35.266 1.00 13.48 ? 639 THR A O 1 ATOM 5071 C CB . THR A 1 639 ? -18.645 5.997 33.306 1.00 12.72 ? 639 THR A CB 1 ATOM 5072 O OG1 . THR A 1 639 ? -18.770 7.076 32.380 1.00 13.85 ? 639 THR A OG1 1 ATOM 5073 C CG2 . THR A 1 639 ? -18.964 6.479 34.731 1.00 13.75 ? 639 THR A CG2 1 ATOM 5074 N N . LEU A 1 640 ? -17.332 3.038 33.756 1.00 12.49 ? 640 LEU A N 1 ATOM 5075 C CA . LEU A 1 640 ? -17.086 1.822 34.549 1.00 11.89 ? 640 LEU A CA 1 ATOM 5076 C C . LEU A 1 640 ? -15.591 1.620 34.779 1.00 11.84 ? 640 LEU A C 1 ATOM 5077 O O . LEU A 1 640 ? -15.178 1.220 35.862 1.00 12.96 ? 640 LEU A O 1 ATOM 5078 C CB . LEU A 1 640 ? -17.653 0.595 33.835 1.00 10.94 ? 640 LEU A CB 1 ATOM 5079 C CG . LEU A 1 640 ? -19.184 0.519 33.701 1.00 9.77 ? 640 LEU A CG 1 ATOM 5080 C CD1 . LEU A 1 640 ? -19.560 -0.817 33.097 1.00 10.18 ? 640 LEU A CD1 1 ATOM 5081 C CD2 . LEU A 1 640 ? -19.815 0.711 35.045 1.00 10.48 ? 640 LEU A CD2 1 ATOM 5082 N N . PHE A 1 641 ? -14.802 1.872 33.753 1.00 11.70 ? 641 PHE A N 1 ATOM 5083 C CA . PHE A 1 641 ? -13.308 1.859 33.882 1.00 12.99 ? 641 PHE A CA 1 ATOM 5084 C C . PHE A 1 641 ? -12.837 2.968 34.782 1.00 12.96 ? 641 PHE A C 1 ATOM 5085 O O . PHE A 1 641 ? -11.873 2.798 35.520 1.00 14.12 ? 641 PHE A O 1 ATOM 5086 C CB . PHE A 1 641 ? -12.647 1.951 32.493 1.00 12.19 ? 641 PHE A CB 1 ATOM 5087 C CG . PHE A 1 641 ? -12.481 0.620 31.817 1.00 13.34 ? 641 PHE A CG 1 ATOM 5088 C CD1 . PHE A 1 641 ? -11.401 -0.220 32.152 1.00 13.13 ? 641 PHE A CD1 1 ATOM 5089 C CD2 . PHE A 1 641 ? -13.338 0.221 30.825 1.00 11.97 ? 641 PHE A CD2 1 ATOM 5090 C CE1 . PHE A 1 641 ? -11.243 -1.450 31.537 1.00 11.32 ? 641 PHE A CE1 1 ATOM 5091 C CE2 . PHE A 1 641 ? -13.183 -0.999 30.196 1.00 14.20 ? 641 PHE A CE2 1 ATOM 5092 C CZ . PHE A 1 641 ? -12.114 -1.846 30.562 1.00 14.69 ? 641 PHE A CZ 1 ATOM 5093 N N . PHE A 1 642 ? -13.525 4.124 34.752 1.00 13.17 ? 642 PHE A N 1 ATOM 5094 C CA . PHE A 1 642 ? -13.149 5.206 35.644 1.00 12.72 ? 642 PHE A CA 1 ATOM 5095 C C . PHE A 1 642 ? -13.396 4.766 37.071 1.00 13.00 ? 642 PHE A C 1 ATOM 5096 O O . PHE A 1 642 ? -12.562 5.028 37.962 1.00 13.03 ? 642 PHE A O 1 ATOM 5097 C CB . PHE A 1 642 ? -13.824 6.557 35.321 1.00 13.01 ? 642 PHE A CB 1 ATOM 5098 C CG . PHE A 1 642 ? -13.901 7.505 36.506 1.00 12.26 ? 642 PHE A CG 1 ATOM 5099 C CD1 . PHE A 1 642 ? -12.761 8.169 36.965 1.00 11.86 ? 642 PHE A CD1 1 ATOM 5100 C CD2 . PHE A 1 642 ? -15.130 7.726 37.164 1.00 13.76 ? 642 PHE A CD2 1 ATOM 5101 C CE1 . PHE A 1 642 ? -12.826 9.054 38.054 1.00 15.01 ? 642 PHE A CE1 1 ATOM 5102 C CE2 . PHE A 1 642 ? -15.208 8.602 38.257 1.00 16.17 ? 642 PHE A CE2 1 ATOM 5103 C CZ . PHE A 1 642 ? -14.049 9.263 38.711 1.00 15.22 ? 642 PHE A CZ 1 ATOM 5104 N N . ARG A 1 643 ? -14.487 4.031 37.295 1.00 12.38 ? 643 ARG A N 1 ATOM 5105 C CA . ARG A 1 643 ? -14.778 3.563 38.650 1.00 11.83 ? 643 ARG A CA 1 ATOM 5106 C C . ARG A 1 643 ? -13.845 2.436 39.072 1.00 11.89 ? 643 ARG A C 1 ATOM 5107 O O . ARG A 1 643 ? -13.492 2.365 40.233 1.00 12.81 ? 643 ARG A O 1 ATOM 5108 C CB . ARG A 1 643 ? -16.268 3.206 38.856 1.00 12.01 ? 643 ARG A CB 1 ATOM 5109 C CG . ARG A 1 643 ? -17.236 4.440 38.856 1.00 13.96 ? 643 ARG A CG 1 ATOM 5110 C CD . ARG A 1 643 ? -16.858 5.515 39.873 1.00 17.74 ? 643 ARG A CD 1 ATOM 5111 N NE . ARG A 1 643 ? -17.972 6.439 40.089 1.00 23.64 ? 643 ARG A NE 1 ATOM 5112 C CZ . ARG A 1 643 ? -17.948 7.520 40.867 1.00 23.86 ? 643 ARG A CZ 1 ATOM 5113 N NH1 . ARG A 1 643 ? -16.862 7.862 41.532 1.00 27.89 ? 643 ARG A NH1 1 ATOM 5114 N NH2 . ARG A 1 643 ? -19.032 8.268 40.974 1.00 25.11 ? 643 ARG A NH2 1 ATOM 5115 N N . ALA A 1 644 ? -13.454 1.564 38.144 1.00 10.29 ? 644 ALA A N 1 ATOM 5116 C CA . ALA A 1 644 ? -12.473 0.517 38.419 1.00 11.70 ? 644 ALA A CA 1 ATOM 5117 C C . ALA A 1 644 ? -11.097 1.134 38.809 1.00 11.80 ? 644 ALA A C 1 ATOM 5118 O O . ALA A 1 644 ? -10.472 0.753 39.799 1.00 11.90 ? 644 ALA A O 1 ATOM 5119 C CB . ALA A 1 644 ? -12.337 -0.439 37.159 1.00 11.03 ? 644 ALA A CB 1 ATOM 5120 N N . HIS A 1 645 ? -10.674 2.133 38.055 1.00 12.48 ? 645 HIS A N 1 ATOM 5121 C CA . HIS A 1 645 ? -9.477 2.908 38.365 1.00 13.43 ? 645 HIS A CA 1 ATOM 5122 C C . HIS A 1 645 ? -9.491 3.738 39.672 1.00 15.07 ? 645 HIS A C 1 ATOM 5123 O O . HIS A 1 645 ? -8.501 3.746 40.406 1.00 16.40 ? 645 HIS A O 1 ATOM 5124 C CB . HIS A 1 645 ? -9.107 3.815 37.178 1.00 13.67 ? 645 HIS A CB 1 ATOM 5125 C CG . HIS A 1 645 ? -7.981 4.754 37.492 1.00 17.04 ? 645 HIS A CG 1 ATOM 5126 N ND1 . HIS A 1 645 ? -6.686 4.319 37.651 1.00 19.27 ? 645 HIS A ND1 1 ATOM 5127 C CD2 . HIS A 1 645 ? -7.964 6.082 37.761 1.00 20.54 ? 645 HIS A CD2 1 ATOM 5128 C CE1 . HIS A 1 645 ? -5.907 5.339 37.971 1.00 19.19 ? 645 HIS A CE1 1 ATOM 5129 N NE2 . HIS A 1 645 ? -6.660 6.422 38.048 1.00 22.71 ? 645 HIS A NE2 1 ATOM 5130 N N . SER A 1 646 ? -10.599 4.415 39.991 1.00 15.29 ? 646 SER A N 1 ATOM 5131 C CA . SER A 1 646 ? -10.628 5.350 41.112 1.00 16.11 ? 646 SER A CA 1 ATOM 5132 C C . SER A 1 646 ? -11.131 4.738 42.428 1.00 16.62 ? 646 SER A C 1 ATOM 5133 O O . SER A 1 646 ? -10.855 5.247 43.513 1.00 16.64 ? 646 SER A O 1 ATOM 5134 C CB . SER A 1 646 ? -11.457 6.595 40.743 1.00 16.92 ? 646 SER A CB 1 ATOM 5135 O OG . SER A 1 646 ? -12.797 6.232 40.420 1.00 17.12 ? 646 SER A OG 1 ATOM 5136 N N . ARG A 1 647 ? -11.844 3.629 42.335 1.00 16.91 ? 647 ARG A N 1 ATOM 5137 C CA . ARG A 1 647 ? -12.542 3.104 43.490 1.00 17.51 ? 647 ARG A CA 1 ATOM 5138 C C . ARG A 1 647 ? -12.344 1.614 43.627 1.00 16.38 ? 647 ARG A C 1 ATOM 5139 O O . ARG A 1 647 ? -12.369 1.083 44.728 1.00 16.24 ? 647 ARG A O 1 ATOM 5140 C CB . ARG A 1 647 ? -14.040 3.451 43.377 1.00 17.09 ? 647 ARG A CB 1 ATOM 5141 C CG . ARG A 1 647 ? -14.869 2.983 44.531 1.00 20.40 ? 647 ARG A CG 1 ATOM 5142 C CD . ARG A 1 647 ? -16.247 3.685 44.514 1.00 23.11 ? 647 ARG A CD 1 ATOM 5143 N NE . ARG A 1 647 ? -17.140 3.167 43.479 1.00 22.21 ? 647 ARG A NE 1 ATOM 5144 C CZ . ARG A 1 647 ? -18.190 3.822 42.973 1.00 24.35 ? 647 ARG A CZ 1 ATOM 5145 N NH1 . ARG A 1 647 ? -18.509 5.040 43.392 1.00 25.53 ? 647 ARG A NH1 1 ATOM 5146 N NH2 . ARG A 1 647 ? -18.927 3.262 42.030 1.00 23.57 ? 647 ARG A NH2 1 ATOM 5147 N N . GLY A 1 648 ? -12.149 0.944 42.495 1.00 16.31 ? 648 GLY A N 1 ATOM 5148 C CA . GLY A 1 648 ? -11.863 -0.483 42.479 1.00 16.77 ? 648 GLY A CA 1 ATOM 5149 C C . GLY A 1 648 ? -13.035 -1.381 42.136 1.00 17.07 ? 648 GLY A C 1 ATOM 5150 O O . GLY A 1 648 ? -13.017 -2.549 42.480 1.00 16.89 ? 648 GLY A O 1 ATOM 5151 N N . ASP A 1 649 ? -14.055 -0.843 41.473 1.00 17.80 ? 649 ASP A N 1 ATOM 5152 C CA . ASP A 1 649 ? -15.163 -1.654 40.992 1.00 18.55 ? 649 ASP A CA 1 ATOM 5153 C C . ASP A 1 649 ? -14.733 -2.575 39.846 1.00 19.18 ? 649 ASP A C 1 ATOM 5154 O O . ASP A 1 649 ? -13.815 -2.255 39.083 1.00 21.35 ? 649 ASP A O 1 ATOM 5155 C CB . ASP A 1 649 ? -16.348 -0.778 40.514 1.00 19.10 ? 649 ASP A CB 1 ATOM 5156 C CG . ASP A 1 649 ? -16.705 0.339 41.470 1.00 20.42 ? 649 ASP A CG 1 ATOM 5157 O OD1 . ASP A 1 649 ? -15.888 0.729 42.318 1.00 25.30 ? 649 ASP A OD1 1 ATOM 5158 O OD2 . ASP A 1 649 ? -17.816 0.876 41.353 1.00 25.55 ? 649 ASP A OD2 1 ATOM 5159 N N . THR A 1 650 ? -15.409 -3.714 39.700 1.00 18.51 ? 650 THR A N 1 ATOM 5160 C CA . THR A 1 650 ? -15.254 -4.550 38.507 1.00 17.24 ? 650 THR A CA 1 ATOM 5161 C C . THR A 1 650 ? -15.877 -3.854 37.284 1.00 16.48 ? 650 THR A C 1 ATOM 5162 O O . THR A 1 650 ? -16.670 -2.929 37.456 1.00 18.43 ? 650 THR A O 1 ATOM 5163 C CB . THR A 1 650 ? -15.908 -5.927 38.706 1.00 17.22 ? 650 THR A CB 1 ATOM 5164 O OG1 . THR A 1 650 ? -17.317 -5.778 39.028 1.00 17.22 ? 650 THR A OG1 1 ATOM 5165 C CG2 . THR A 1 650 ? -15.209 -6.672 39.823 1.00 16.73 ? 650 THR A CG2 1 ATOM 5166 N N . VAL A 1 651 ? -15.534 -4.291 36.073 1.00 15.16 ? 651 VAL A N 1 ATOM 5167 C CA . VAL A 1 651 ? -16.112 -3.762 34.845 1.00 14.17 ? 651 VAL A CA 1 ATOM 5168 C C . VAL A 1 651 ? -17.057 -4.811 34.280 1.00 15.37 ? 651 VAL A C 1 ATOM 5169 O O . VAL A 1 651 ? -18.255 -4.563 34.274 1.00 14.45 ? 651 VAL A O 1 ATOM 5170 C CB . VAL A 1 651 ? -15.084 -3.248 33.800 1.00 15.36 ? 651 VAL A CB 1 ATOM 5171 C CG1 . VAL A 1 651 ? -15.784 -2.854 32.511 1.00 14.58 ? 651 VAL A CG1 1 ATOM 5172 C CG2 . VAL A 1 651 ? -14.290 -2.075 34.339 1.00 11.96 ? 651 VAL A CG2 1 ATOM 5173 N N . ALA A 1 652 ? -16.529 -5.957 33.819 1.00 15.29 ? 652 ALA A N 1 ATOM 5174 C CA . ALA A 1 652 ? -17.354 -7.137 33.555 1.00 15.63 ? 652 ALA A CA 1 ATOM 5175 C C . ALA A 1 652 ? -17.585 -7.744 34.944 1.00 16.00 ? 652 ALA A C 1 ATOM 5176 O O . ALA A 1 652 ? -16.633 -8.002 35.687 1.00 13.95 ? 652 ALA A O 1 ATOM 5177 C CB . ALA A 1 652 ? -16.624 -8.145 32.642 1.00 16.13 ? 652 ALA A CB 1 ATOM 5178 N N . ARG A 1 653 ? -18.856 -7.932 35.291 1.00 14.57 ? 653 ARG A N 1 ATOM 5179 C CA . ARG A 1 653 ? -19.258 -8.219 36.641 1.00 13.93 ? 653 ARG A CA 1 ATOM 5180 C C . ARG A 1 653 ? -20.149 -9.468 36.668 1.00 14.53 ? 653 ARG A C 1 ATOM 5181 O O . ARG A 1 653 ? -21.040 -9.643 35.797 1.00 14.21 ? 653 ARG A O 1 ATOM 5182 C CB . ARG A 1 653 ? -20.010 -6.986 37.207 1.00 14.64 ? 653 ARG A CB 1 ATOM 5183 C CG . ARG A 1 653 ? -20.173 -6.947 38.719 1.00 12.84 ? 653 ARG A CG 1 ATOM 5184 C CD . ARG A 1 653 ? -20.828 -5.665 39.150 1.00 14.15 ? 653 ARG A CD 1 ATOM 5185 N NE . ARG A 1 653 ? -19.924 -4.540 38.943 1.00 11.08 ? 653 ARG A NE 1 ATOM 5186 C CZ . ARG A 1 653 ? -20.246 -3.268 39.113 1.00 13.87 ? 653 ARG A CZ 1 ATOM 5187 N NH1 . ARG A 1 653 ? -21.482 -2.885 39.496 1.00 12.62 ? 653 ARG A NH1 1 ATOM 5188 N NH2 . ARG A 1 653 ? -19.314 -2.370 38.889 1.00 13.76 ? 653 ARG A NH2 1 ATOM 5189 N N . PRO A 1 654 ? -19.925 -10.349 37.677 1.00 14.11 ? 654 PRO A N 1 ATOM 5190 C CA . PRO A 1 654 ? -20.819 -11.480 37.870 1.00 13.41 ? 654 PRO A CA 1 ATOM 5191 C C . PRO A 1 654 ? -22.188 -10.947 38.255 1.00 13.47 ? 654 PRO A C 1 ATOM 5192 O O . PRO A 1 654 ? -22.270 -9.914 38.911 1.00 13.24 ? 654 PRO A O 1 ATOM 5193 C CB . PRO A 1 654 ? -20.198 -12.213 39.052 1.00 13.92 ? 654 PRO A CB 1 ATOM 5194 C CG . PRO A 1 654 ? -18.678 -11.753 39.044 1.00 12.70 ? 654 PRO A CG 1 ATOM 5195 C CD . PRO A 1 654 ? -18.850 -10.313 38.684 1.00 13.94 ? 654 PRO A CD 1 ATOM 5196 N N . LEU A 1 655 ? -23.243 -11.625 37.818 1.00 13.60 ? 655 LEU A N 1 ATOM 5197 C CA . LEU A 1 655 ? -24.610 -11.334 38.289 1.00 14.12 ? 655 LEU A CA 1 ATOM 5198 C C . LEU A 1 655 ? -24.715 -11.316 39.799 1.00 14.37 ? 655 LEU A C 1 ATOM 5199 O O . LEU A 1 655 ? -25.424 -10.491 40.349 1.00 14.78 ? 655 LEU A O 1 ATOM 5200 C CB . LEU A 1 655 ? -25.606 -12.364 37.738 1.00 14.35 ? 655 LEU A CB 1 ATOM 5201 C CG . LEU A 1 655 ? -26.295 -12.070 36.407 1.00 13.59 ? 655 LEU A CG 1 ATOM 5202 C CD1 . LEU A 1 655 ? -25.293 -11.874 35.296 1.00 15.76 ? 655 LEU A CD1 1 ATOM 5203 C CD2 . LEU A 1 655 ? -27.249 -13.257 36.043 1.00 14.42 ? 655 LEU A CD2 1 ATOM 5204 N N . LEU A 1 656 ? -23.977 -12.201 40.479 1.00 14.92 ? 656 LEU A N 1 ATOM 5205 C CA . LEU A 1 656 ? -24.077 -12.312 41.935 1.00 15.08 ? 656 LEU A CA 1 ATOM 5206 C C . LEU A 1 656 ? -23.553 -11.067 42.677 1.00 15.66 ? 656 LEU A C 1 ATOM 5207 O O . LEU A 1 656 ? -23.885 -10.854 43.843 1.00 16.67 ? 656 LEU A O 1 ATOM 5208 C CB . LEU A 1 656 ? -23.374 -13.588 42.443 1.00 15.40 ? 656 LEU A CB 1 ATOM 5209 C CG . LEU A 1 656 ? -21.839 -13.568 42.361 1.00 16.95 ? 656 LEU A CG 1 ATOM 5210 C CD1 . LEU A 1 656 ? -21.219 -13.254 43.753 1.00 18.81 ? 656 LEU A CD1 1 ATOM 5211 C CD2 . LEU A 1 656 ? -21.339 -14.888 41.816 1.00 17.68 ? 656 LEU A CD2 1 ATOM 5212 N N . HIS A 1 657 ? -22.740 -10.247 42.012 1.00 14.99 ? 657 HIS A N 1 ATOM 5213 C CA . HIS A 1 657 ? -22.224 -9.034 42.637 1.00 14.46 ? 657 HIS A CA 1 ATOM 5214 C C . HIS A 1 657 ? -23.298 -7.968 42.767 1.00 13.99 ? 657 HIS A C 1 ATOM 5215 O O . HIS A 1 657 ? -23.221 -7.115 43.646 1.00 13.01 ? 657 HIS A O 1 ATOM 5216 C CB . HIS A 1 657 ? -21.045 -8.488 41.847 1.00 14.93 ? 657 HIS A CB 1 ATOM 5217 C CG . HIS A 1 657 ? -19.771 -9.217 42.107 1.00 13.60 ? 657 HIS A CG 1 ATOM 5218 N ND1 . HIS A 1 657 ? -18.551 -8.580 42.137 1.00 11.15 ? 657 HIS A ND1 1 ATOM 5219 C CD2 . HIS A 1 657 ? -19.529 -10.515 42.394 1.00 14.11 ? 657 HIS A CD2 1 ATOM 5220 C CE1 . HIS A 1 657 ? -17.604 -9.460 42.417 1.00 15.13 ? 657 HIS A CE1 1 ATOM 5221 N NE2 . HIS A 1 657 ? -18.172 -10.638 42.591 1.00 16.09 ? 657 HIS A NE2 1 ATOM 5222 N N . GLU A 1 658 ? -24.321 -8.070 41.920 1.00 13.81 ? 658 GLU A N 1 ATOM 5223 C CA . GLU A 1 658 ? -25.445 -7.167 41.957 1.00 14.92 ? 658 GLU A CA 1 ATOM 5224 C C . GLU A 1 658 ? -26.658 -7.828 42.612 1.00 15.12 ? 658 GLU A C 1 ATOM 5225 O O . GLU A 1 658 ? -27.482 -7.142 43.195 1.00 16.89 ? 658 GLU A O 1 ATOM 5226 C CB . GLU A 1 658 ? -25.800 -6.684 40.533 1.00 14.98 ? 658 GLU A CB 1 ATOM 5227 C CG . GLU A 1 658 ? -24.816 -5.648 39.918 1.00 16.43 ? 658 GLU A CG 1 ATOM 5228 C CD . GLU A 1 658 ? -24.673 -4.410 40.766 1.00 18.56 ? 658 GLU A CD 1 ATOM 5229 O OE1 . GLU A 1 658 ? -25.714 -3.819 41.172 1.00 18.94 ? 658 GLU A OE1 1 ATOM 5230 O OE2 . GLU A 1 658 ? -23.514 -4.018 41.037 1.00 20.78 ? 658 GLU A OE2 1 ATOM 5231 N N . PHE A 1 659 ? -26.743 -9.147 42.524 1.00 15.08 ? 659 PHE A N 1 ATOM 5232 C CA . PHE A 1 659 ? -27.949 -9.902 42.910 1.00 15.71 ? 659 PHE A CA 1 ATOM 5233 C C . PHE A 1 659 ? -27.655 -11.041 43.890 1.00 15.78 ? 659 PHE A C 1 ATOM 5234 O O . PHE A 1 659 ? -28.325 -12.089 43.863 1.00 14.78 ? 659 PHE A O 1 ATOM 5235 C CB . PHE A 1 659 ? -28.671 -10.405 41.645 1.00 14.35 ? 659 PHE A CB 1 ATOM 5236 C CG . PHE A 1 659 ? -29.004 -9.305 40.677 1.00 14.32 ? 659 PHE A CG 1 ATOM 5237 C CD1 . PHE A 1 659 ? -30.026 -8.408 40.963 1.00 17.63 ? 659 PHE A CD1 1 ATOM 5238 C CD2 . PHE A 1 659 ? -28.306 -9.169 39.468 1.00 15.84 ? 659 PHE A CD2 1 ATOM 5239 C CE1 . PHE A 1 659 ? -30.348 -7.383 40.075 1.00 14.87 ? 659 PHE A CE1 1 ATOM 5240 C CE2 . PHE A 1 659 ? -28.641 -8.135 38.569 1.00 14.16 ? 659 PHE A CE2 1 ATOM 5241 C CZ . PHE A 1 659 ? -29.647 -7.249 38.897 1.00 14.29 ? 659 PHE A CZ 1 ATOM 5242 N N . TYR A 1 660 ? -26.660 -10.806 44.762 1.00 15.88 ? 660 TYR A N 1 ATOM 5243 C CA . TYR A 1 660 ? -26.185 -11.778 45.785 1.00 17.06 ? 660 TYR A CA 1 ATOM 5244 C C . TYR A 1 660 ? -27.269 -12.231 46.739 1.00 17.65 ? 660 TYR A C 1 ATOM 5245 O O . TYR A 1 660 ? -27.130 -13.273 47.344 1.00 16.88 ? 660 TYR A O 1 ATOM 5246 C CB . TYR A 1 660 ? -25.016 -11.200 46.612 1.00 15.98 ? 660 TYR A CB 1 ATOM 5247 C CG . TYR A 1 660 ? -25.242 -9.768 46.990 1.00 17.76 ? 660 TYR A CG 1 ATOM 5248 C CD1 . TYR A 1 660 ? -26.064 -9.423 48.066 1.00 16.31 ? 660 TYR A CD1 1 ATOM 5249 C CD2 . TYR A 1 660 ? -24.656 -8.738 46.251 1.00 19.48 ? 660 TYR A CD2 1 ATOM 5250 C CE1 . TYR A 1 660 ? -26.298 -8.095 48.402 1.00 18.44 ? 660 TYR A CE1 1 ATOM 5251 C CE2 . TYR A 1 660 ? -24.895 -7.413 46.572 1.00 19.72 ? 660 TYR A CE2 1 ATOM 5252 C CZ . TYR A 1 660 ? -25.703 -7.099 47.654 1.00 18.45 ? 660 TYR A CZ 1 ATOM 5253 O OH . TYR A 1 660 ? -25.900 -5.777 47.980 1.00 19.49 ? 660 TYR A OH 1 ATOM 5254 N N . GLU A 1 661 ? -28.344 -11.447 46.862 1.00 19.91 ? 661 GLU A N 1 ATOM 5255 C CA . GLU A 1 661 ? -29.500 -11.808 47.705 1.00 21.94 ? 661 GLU A CA 1 ATOM 5256 C C . GLU A 1 661 ? -30.240 -12.989 47.097 1.00 21.02 ? 661 GLU A C 1 ATOM 5257 O O . GLU A 1 661 ? -31.020 -13.675 47.777 1.00 21.70 ? 661 GLU A O 1 ATOM 5258 C CB . GLU A 1 661 ? -30.462 -10.618 47.915 1.00 21.50 ? 661 GLU A CB 1 ATOM 5259 C CG . GLU A 1 661 ? -29.902 -9.517 48.847 1.00 26.09 ? 661 GLU A CG 1 ATOM 5260 C CD . GLU A 1 661 ? -30.906 -8.418 49.218 1.00 27.30 ? 661 GLU A CD 1 ATOM 5261 O OE1 . GLU A 1 661 ? -32.004 -8.337 48.606 1.00 35.84 ? 661 GLU A OE1 1 ATOM 5262 O OE2 . GLU A 1 661 ? -30.605 -7.623 50.142 1.00 35.51 ? 661 GLU A OE2 1 ATOM 5263 N N . ASP A 1 662 ? -29.954 -13.230 45.823 1.00 19.98 ? 662 ASP A N 1 ATOM 5264 C CA . ASP A 1 662 ? -30.596 -14.257 45.025 1.00 19.13 ? 662 ASP A CA 1 ATOM 5265 C C . ASP A 1 662 ? -29.651 -15.422 44.732 1.00 19.18 ? 662 ASP A C 1 ATOM 5266 O O . ASP A 1 662 ? -28.851 -15.352 43.809 1.00 17.95 ? 662 ASP A O 1 ATOM 5267 C CB . ASP A 1 662 ? -31.084 -13.603 43.724 1.00 18.38 ? 662 ASP A CB 1 ATOM 5268 C CG . ASP A 1 662 ? -31.879 -14.538 42.845 1.00 17.52 ? 662 ASP A CG 1 ATOM 5269 O OD1 . ASP A 1 662 ? -31.956 -15.732 43.173 1.00 15.77 ? 662 ASP A OD1 1 ATOM 5270 O OD2 . ASP A 1 662 ? -32.448 -14.056 41.829 1.00 16.90 ? 662 ASP A OD2 1 ATOM 5271 N N . ASN A 1 663 ? -29.765 -16.511 45.504 1.00 20.16 ? 663 ASN A N 1 ATOM 5272 C CA . ASN A 1 663 ? -28.856 -17.653 45.387 1.00 20.75 ? 663 ASN A CA 1 ATOM 5273 C C . ASN A 1 663 ? -28.802 -18.314 43.989 1.00 20.34 ? 663 ASN A C 1 ATOM 5274 O O . ASN A 1 663 ? -27.804 -18.969 43.652 1.00 19.84 ? 663 ASN A O 1 ATOM 5275 C CB . ASN A 1 663 ? -29.129 -18.709 46.490 1.00 21.62 ? 663 ASN A CB 1 ATOM 5276 C CG . ASN A 1 663 ? -30.382 -19.528 46.220 1.00 24.13 ? 663 ASN A CG 1 ATOM 5277 O OD1 . ASN A 1 663 ? -31.438 -18.988 45.853 1.00 27.28 ? 663 ASN A OD1 1 ATOM 5278 N ND2 . ASN A 1 663 ? -30.269 -20.846 46.387 1.00 27.49 ? 663 ASN A ND2 1 ATOM 5279 N N . SER A 1 664 ? -29.848 -18.123 43.175 1.00 19.84 ? 664 SER A N 1 ATOM 5280 C CA . SER A 1 664 ? -29.843 -18.614 41.785 1.00 20.12 ? 664 SER A CA 1 ATOM 5281 C C . SER A 1 664 ? -28.776 -17.954 40.923 1.00 19.24 ? 664 SER A C 1 ATOM 5282 O O . SER A 1 664 ? -28.489 -18.436 39.837 1.00 19.74 ? 664 SER A O 1 ATOM 5283 C CB . SER A 1 664 ? -31.198 -18.405 41.091 1.00 20.31 ? 664 SER A CB 1 ATOM 5284 O OG . SER A 1 664 ? -32.179 -19.216 41.662 1.00 19.23 ? 664 SER A OG 1 ATOM 5285 N N . THR A 1 665 ? -28.214 -16.844 41.393 1.00 18.87 ? 665 THR A N 1 ATOM 5286 C CA . THR A 1 665 ? -27.206 -16.135 40.624 1.00 18.46 ? 665 THR A CA 1 ATOM 5287 C C . THR A 1 665 ? -25.778 -16.584 41.052 1.00 18.72 ? 665 THR A C 1 ATOM 5288 O O . THR A 1 665 ? -24.818 -16.189 40.430 1.00 19.21 ? 665 THR A O 1 ATOM 5289 C CB . THR A 1 665 ? -27.309 -14.621 40.799 1.00 17.94 ? 665 THR A CB 1 ATOM 5290 O OG1 . THR A 1 665 ? -26.963 -14.281 42.149 1.00 19.61 ? 665 THR A OG1 1 ATOM 5291 C CG2 . THR A 1 665 ? -28.719 -14.052 40.427 1.00 18.23 ? 665 THR A CG2 1 ATOM 5292 N N . TRP A 1 666 ? -25.658 -17.378 42.123 1.00 18.51 ? 666 TRP A N 1 ATOM 5293 C CA . TRP A 1 666 ? -24.363 -17.685 42.747 1.00 18.59 ? 666 TRP A CA 1 ATOM 5294 C C . TRP A 1 666 ? -23.390 -18.522 41.874 1.00 18.58 ? 666 TRP A C 1 ATOM 5295 O O . TRP A 1 666 ? -22.180 -18.472 42.041 1.00 19.12 ? 666 TRP A O 1 ATOM 5296 C CB . TRP A 1 666 ? -24.544 -18.346 44.127 1.00 18.04 ? 666 TRP A CB 1 ATOM 5297 C CG . TRP A 1 666 ? -25.112 -17.441 45.258 1.00 18.24 ? 666 TRP A CG 1 ATOM 5298 C CD1 . TRP A 1 666 ? -25.417 -16.109 45.193 1.00 17.56 ? 666 TRP A CD1 1 ATOM 5299 C CD2 . TRP A 1 666 ? -25.397 -17.847 46.605 1.00 16.82 ? 666 TRP A CD2 1 ATOM 5300 N NE1 . TRP A 1 666 ? -25.913 -15.671 46.410 1.00 17.48 ? 666 TRP A NE1 1 ATOM 5301 C CE2 . TRP A 1 666 ? -25.898 -16.721 47.291 1.00 18.44 ? 666 TRP A CE2 1 ATOM 5302 C CE3 . TRP A 1 666 ? -25.313 -19.071 47.289 1.00 19.75 ? 666 TRP A CE3 1 ATOM 5303 C CZ2 . TRP A 1 666 ? -26.291 -16.775 48.634 1.00 19.05 ? 666 TRP A CZ2 1 ATOM 5304 C CZ3 . TRP A 1 666 ? -25.705 -19.120 48.629 1.00 18.17 ? 666 TRP A CZ3 1 ATOM 5305 C CH2 . TRP A 1 666 ? -26.175 -17.975 49.283 1.00 18.28 ? 666 TRP A CH2 1 ATOM 5306 N N . ASP A 1 667 ? -23.925 -19.293 40.956 1.00 19.08 ? 667 ASP A N 1 ATOM 5307 C CA . ASP A 1 667 ? -23.078 -20.051 40.083 1.00 20.45 ? 667 ASP A CA 1 ATOM 5308 C C . ASP A 1 667 ? -23.291 -19.714 38.628 1.00 19.75 ? 667 ASP A C 1 ATOM 5309 O O . ASP A 1 667 ? -22.839 -20.459 37.772 1.00 20.07 ? 667 ASP A O 1 ATOM 5310 C CB . ASP A 1 667 ? -23.246 -21.544 40.332 1.00 21.99 ? 667 ASP A CB 1 ATOM 5311 C CG . ASP A 1 667 ? -24.650 -22.026 40.047 1.00 26.97 ? 667 ASP A CG 1 ATOM 5312 O OD1 . ASP A 1 667 ? -25.503 -21.182 39.645 1.00 32.41 ? 667 ASP A OD1 1 ATOM 5313 O OD2 . ASP A 1 667 ? -24.873 -23.252 40.200 1.00 31.44 ? 667 ASP A OD2 1 ATOM 5314 N N . VAL A 1 668 ? -23.982 -18.602 38.344 1.00 19.03 ? 668 VAL A N 1 ATOM 5315 C CA . VAL A 1 668 ? -24.214 -18.185 36.964 1.00 18.65 ? 668 VAL A CA 1 ATOM 5316 C C . VAL A 1 668 ? -22.912 -17.709 36.362 1.00 18.97 ? 668 VAL A C 1 ATOM 5317 O O . VAL A 1 668 ? -22.276 -16.822 36.904 1.00 19.72 ? 668 VAL A O 1 ATOM 5318 C CB . VAL A 1 668 ? -25.309 -17.112 36.857 1.00 19.07 ? 668 VAL A CB 1 ATOM 5319 C CG1 . VAL A 1 668 ? -25.293 -16.452 35.492 1.00 17.00 ? 668 VAL A CG1 1 ATOM 5320 C CG2 . VAL A 1 668 ? -26.642 -17.769 37.120 1.00 19.20 ? 668 VAL A CG2 1 ATOM 5321 N N . HIS A 1 669 ? -22.528 -18.325 35.249 1.00 19.80 ? 669 HIS A N 1 ATOM 5322 C CA . HIS A 1 669 ? -21.256 -18.059 34.572 1.00 21.38 ? 669 HIS A CA 1 ATOM 5323 C C . HIS A 1 669 ? -21.430 -18.040 33.038 1.00 20.89 ? 669 HIS A C 1 ATOM 5324 O O . HIS A 1 669 ? -20.457 -17.996 32.302 1.00 20.63 ? 669 HIS A O 1 ATOM 5325 C CB . HIS A 1 669 ? -20.213 -19.113 34.989 1.00 21.20 ? 669 HIS A CB 1 ATOM 5326 C CG . HIS A 1 669 ? -20.613 -20.520 34.673 1.00 23.10 ? 669 HIS A CG 1 ATOM 5327 N ND1 . HIS A 1 669 ? -20.262 -21.147 33.496 1.00 26.53 ? 669 HIS A ND1 1 ATOM 5328 C CD2 . HIS A 1 669 ? -21.348 -21.418 35.367 1.00 24.91 ? 669 HIS A CD2 1 ATOM 5329 C CE1 . HIS A 1 669 ? -20.769 -22.366 33.478 1.00 26.10 ? 669 HIS A CE1 1 ATOM 5330 N NE2 . HIS A 1 669 ? -21.422 -22.560 34.607 1.00 25.87 ? 669 HIS A NE2 1 ATOM 5331 N N . GLN A 1 670 ? -22.672 -18.114 32.572 1.00 19.99 ? 670 GLN A N 1 ATOM 5332 C CA . GLN A 1 670 ? -22.985 -18.089 31.134 1.00 20.68 ? 670 GLN A CA 1 ATOM 5333 C C . GLN A 1 670 ? -23.561 -16.729 30.695 1.00 18.90 ? 670 GLN A C 1 ATOM 5334 O O . GLN A 1 670 ? -23.822 -16.487 29.510 1.00 17.83 ? 670 GLN A O 1 ATOM 5335 C CB . GLN A 1 670 ? -23.916 -19.273 30.752 1.00 21.16 ? 670 GLN A CB 1 ATOM 5336 C CG . GLN A 1 670 ? -23.142 -20.616 30.645 1.00 22.85 ? 670 GLN A CG 1 ATOM 5337 C CD . GLN A 1 670 ? -23.853 -21.729 29.829 1.00 25.02 ? 670 GLN A CD 1 ATOM 5338 O OE1 . GLN A 1 670 ? -23.223 -22.745 29.500 1.00 30.73 ? 670 GLN A OE1 1 ATOM 5339 N NE2 . GLN A 1 670 ? -25.148 -21.546 29.512 1.00 28.27 ? 670 GLN A NE2 1 ATOM 5340 N N . GLN A 1 671 ? -23.725 -15.846 31.678 1.00 17.62 ? 671 GLN A N 1 ATOM 5341 C CA . GLN A 1 671 ? -24.148 -14.477 31.477 1.00 17.17 ? 671 GLN A CA 1 ATOM 5342 C C . GLN A 1 671 ? -23.238 -13.625 32.323 1.00 16.66 ? 671 GLN A C 1 ATOM 5343 O O . GLN A 1 671 ? -22.630 -14.125 33.262 1.00 17.52 ? 671 GLN A O 1 ATOM 5344 C CB . GLN A 1 671 ? -25.585 -14.286 31.988 1.00 17.10 ? 671 GLN A CB 1 ATOM 5345 C CG . GLN A 1 671 ? -26.633 -15.049 31.221 1.00 18.02 ? 671 GLN A CG 1 ATOM 5346 C CD . GLN A 1 671 ? -27.979 -14.960 31.912 1.00 17.91 ? 671 GLN A CD 1 ATOM 5347 O OE1 . GLN A 1 671 ? -28.283 -15.741 32.830 1.00 17.66 ? 671 GLN A OE1 1 ATOM 5348 N NE2 . GLN A 1 671 ? -28.781 -13.995 31.495 1.00 17.98 ? 671 GLN A NE2 1 ATOM 5349 N N . PHE A 1 672 ? -23.137 -12.344 32.000 1.00 15.92 ? 672 PHE A N 1 ATOM 5350 C CA . PHE A 1 672 ? -22.458 -11.398 32.874 1.00 15.53 ? 672 PHE A CA 1 ATOM 5351 C C . PHE A 1 672 ? -23.039 -10.002 32.700 1.00 15.81 ? 672 PHE A C 1 ATOM 5352 O O . PHE A 1 672 ? -23.897 -9.760 31.840 1.00 15.88 ? 672 PHE A O 1 ATOM 5353 C CB . PHE A 1 672 ? -20.924 -11.434 32.721 1.00 15.51 ? 672 PHE A CB 1 ATOM 5354 C CG . PHE A 1 672 ? -20.435 -10.961 31.398 1.00 16.13 ? 672 PHE A CG 1 ATOM 5355 C CD1 . PHE A 1 672 ? -19.851 -9.716 31.273 1.00 14.16 ? 672 PHE A CD1 1 ATOM 5356 C CD2 . PHE A 1 672 ? -20.512 -11.780 30.288 1.00 15.16 ? 672 PHE A CD2 1 ATOM 5357 C CE1 . PHE A 1 672 ? -19.408 -9.274 30.057 1.00 12.00 ? 672 PHE A CE1 1 ATOM 5358 C CE2 . PHE A 1 672 ? -20.069 -11.349 29.069 1.00 15.83 ? 672 PHE A CE2 1 ATOM 5359 C CZ . PHE A 1 672 ? -19.525 -10.070 28.954 1.00 15.18 ? 672 PHE A CZ 1 ATOM 5360 N N . LEU A 1 673 ? -22.604 -9.089 33.552 1.00 15.61 ? 673 LEU A N 1 ATOM 5361 C CA . LEU A 1 673 ? -23.000 -7.707 33.430 1.00 15.15 ? 673 LEU A CA 1 ATOM 5362 C C . LEU A 1 673 ? -21.849 -6.807 32.990 1.00 14.93 ? 673 LEU A C 1 ATOM 5363 O O . LEU A 1 673 ? -20.679 -7.078 33.285 1.00 14.51 ? 673 LEU A O 1 ATOM 5364 C CB . LEU A 1 673 ? -23.515 -7.224 34.772 1.00 15.74 ? 673 LEU A CB 1 ATOM 5365 C CG . LEU A 1 673 ? -24.413 -8.145 35.598 1.00 16.22 ? 673 LEU A CG 1 ATOM 5366 C CD1 . LEU A 1 673 ? -24.414 -7.618 36.997 1.00 15.36 ? 673 LEU A CD1 1 ATOM 5367 C CD2 . LEU A 1 673 ? -25.814 -8.109 35.039 1.00 18.88 ? 673 LEU A CD2 1 ATOM 5368 N N . TRP A 1 674 ? -22.176 -5.736 32.284 1.00 14.57 ? 674 TRP A N 1 ATOM 5369 C CA . TRP A 1 674 ? -21.288 -4.577 32.270 1.00 15.03 ? 674 TRP A CA 1 ATOM 5370 C C . TRP A 1 674 ? -21.689 -3.735 33.456 1.00 16.12 ? 674 TRP A C 1 ATOM 5371 O O . TRP A 1 674 ? -22.814 -3.212 33.469 1.00 16.56 ? 674 TRP A O 1 ATOM 5372 C CB . TRP A 1 674 ? -21.503 -3.733 31.027 1.00 14.62 ? 674 TRP A CB 1 ATOM 5373 C CG . TRP A 1 674 ? -20.707 -4.123 29.837 1.00 13.71 ? 674 TRP A CG 1 ATOM 5374 C CD1 . TRP A 1 674 ? -20.063 -5.307 29.621 1.00 15.45 ? 674 TRP A CD1 1 ATOM 5375 C CD2 . TRP A 1 674 ? -20.484 -3.322 28.669 1.00 14.69 ? 674 TRP A CD2 1 ATOM 5376 N NE1 . TRP A 1 674 ? -19.449 -5.290 28.396 1.00 15.47 ? 674 TRP A NE1 1 ATOM 5377 C CE2 . TRP A 1 674 ? -19.686 -4.082 27.791 1.00 12.92 ? 674 TRP A CE2 1 ATOM 5378 C CE3 . TRP A 1 674 ? -20.896 -2.039 28.276 1.00 15.36 ? 674 TRP A CE3 1 ATOM 5379 C CZ2 . TRP A 1 674 ? -19.301 -3.613 26.536 1.00 12.86 ? 674 TRP A CZ2 1 ATOM 5380 C CZ3 . TRP A 1 674 ? -20.506 -1.569 27.033 1.00 14.15 ? 674 TRP A CZ3 1 ATOM 5381 C CH2 . TRP A 1 674 ? -19.692 -2.350 26.187 1.00 15.25 ? 674 TRP A CH2 1 ATOM 5382 N N . GLY A 1 675 ? -20.811 -3.598 34.455 1.00 15.42 ? 675 GLY A N 1 ATOM 5383 C CA . GLY A 1 675 ? -21.168 -2.759 35.591 1.00 16.04 ? 675 GLY A CA 1 ATOM 5384 C C . GLY A 1 675 ? -22.531 -3.177 36.166 1.00 16.37 ? 675 GLY A C 1 ATOM 5385 O O . GLY A 1 675 ? -22.903 -4.344 36.107 1.00 14.80 ? 675 GLY A O 1 ATOM 5386 N N . PRO A 1 676 ? -23.250 -2.234 36.776 1.00 16.94 ? 676 PRO A N 1 ATOM 5387 C CA . PRO A 1 676 ? -24.445 -2.650 37.473 1.00 18.26 ? 676 PRO A CA 1 ATOM 5388 C C . PRO A 1 676 ? -25.689 -2.883 36.574 1.00 18.55 ? 676 PRO A C 1 ATOM 5389 O O . PRO A 1 676 ? -26.633 -3.562 37.000 1.00 19.13 ? 676 PRO A O 1 ATOM 5390 C CB . PRO A 1 676 ? -24.663 -1.502 38.456 1.00 19.26 ? 676 PRO A CB 1 ATOM 5391 C CG . PRO A 1 676 ? -24.156 -0.291 37.701 1.00 18.23 ? 676 PRO A CG 1 ATOM 5392 C CD . PRO A 1 676 ? -22.984 -0.788 36.908 1.00 17.26 ? 676 PRO A CD 1 ATOM 5393 N N . GLY A 1 677 ? -25.676 -2.392 35.334 1.00 18.67 ? 677 GLY A N 1 ATOM 5394 C CA . GLY A 1 677 ? -26.960 -2.206 34.604 1.00 18.16 ? 677 GLY A CA 1 ATOM 5395 C C . GLY A 1 677 ? -27.239 -2.879 33.268 1.00 17.61 ? 677 GLY A C 1 ATOM 5396 O O . GLY A 1 677 ? -28.384 -2.850 32.787 1.00 17.58 ? 677 GLY A O 1 ATOM 5397 N N . LEU A 1 678 ? -26.214 -3.466 32.654 1.00 17.42 ? 678 LEU A N 1 ATOM 5398 C CA . LEU A 1 678 ? -26.360 -4.177 31.359 1.00 16.74 ? 678 LEU A CA 1 ATOM 5399 C C . LEU A 1 678 ? -26.094 -5.681 31.461 1.00 16.57 ? 678 LEU A C 1 ATOM 5400 O O . LEU A 1 678 ? -24.954 -6.129 31.727 1.00 16.28 ? 678 LEU A O 1 ATOM 5401 C CB . LEU A 1 678 ? -25.469 -3.560 30.271 1.00 16.99 ? 678 LEU A CB 1 ATOM 5402 C CG . LEU A 1 678 ? -25.385 -4.257 28.897 1.00 16.87 ? 678 LEU A CG 1 ATOM 5403 C CD1 . LEU A 1 678 ? -26.653 -4.014 28.075 1.00 15.78 ? 678 LEU A CD1 1 ATOM 5404 C CD2 . LEU A 1 678 ? -24.205 -3.727 28.151 1.00 15.12 ? 678 LEU A CD2 1 ATOM 5405 N N . LEU A 1 679 ? -27.147 -6.448 31.207 1.00 15.38 ? 679 LEU A N 1 ATOM 5406 C CA . LEU A 1 679 ? -27.108 -7.894 31.238 1.00 14.83 ? 679 LEU A CA 1 ATOM 5407 C C . LEU A 1 679 ? -26.893 -8.501 29.851 1.00 15.12 ? 679 LEU A C 1 ATOM 5408 O O . LEU A 1 679 ? -27.667 -8.261 28.938 1.00 14.04 ? 679 LEU A O 1 ATOM 5409 C CB . LEU A 1 679 ? -28.432 -8.392 31.844 1.00 14.44 ? 679 LEU A CB 1 ATOM 5410 C CG . LEU A 1 679 ? -28.657 -9.885 31.801 1.00 13.85 ? 679 LEU A CG 1 ATOM 5411 C CD1 . LEU A 1 679 ? -27.629 -10.580 32.722 1.00 10.43 ? 679 LEU A CD1 1 ATOM 5412 C CD2 . LEU A 1 679 ? -30.098 -10.220 32.206 1.00 13.96 ? 679 LEU A CD2 1 ATOM 5413 N N . ILE A 1 680 ? -25.818 -9.286 29.703 1.00 16.17 ? 680 ILE A N 1 ATOM 5414 C CA . ILE A 1 680 ? -25.405 -9.874 28.436 1.00 16.63 ? 680 ILE A CA 1 ATOM 5415 C C . ILE A 1 680 ? -25.686 -11.372 28.513 1.00 16.77 ? 680 ILE A C 1 ATOM 5416 O O . ILE A 1 680 ? -25.143 -12.058 29.382 1.00 16.77 ? 680 ILE A O 1 ATOM 5417 C CB . ILE A 1 680 ? -23.856 -9.576 28.124 1.00 17.20 ? 680 ILE A CB 1 ATOM 5418 C CG1 . ILE A 1 680 ? -23.648 -8.067 27.947 1.00 19.21 ? 680 ILE A CG1 1 ATOM 5419 C CG2 . ILE A 1 680 ? -23.425 -10.210 26.834 1.00 16.20 ? 680 ILE A CG2 1 ATOM 5420 C CD1 . ILE A 1 680 ? -22.483 -7.493 28.696 1.00 17.23 ? 680 ILE A CD1 1 ATOM 5421 N N . THR A 1 681 ? -26.519 -11.865 27.593 1.00 16.16 ? 681 THR A N 1 ATOM 5422 C CA . THR A 1 681 ? -26.912 -13.270 27.520 1.00 16.31 ? 681 THR A CA 1 ATOM 5423 C C . THR A 1 681 ? -26.569 -13.878 26.147 1.00 15.98 ? 681 THR A C 1 ATOM 5424 O O . THR A 1 681 ? -27.382 -13.818 25.205 1.00 16.07 ? 681 THR A O 1 ATOM 5425 C CB . THR A 1 681 ? -28.451 -13.425 27.846 1.00 16.23 ? 681 THR A CB 1 ATOM 5426 O OG1 . THR A 1 681 ? -28.737 -12.764 29.085 1.00 18.28 ? 681 THR A OG1 1 ATOM 5427 C CG2 . THR A 1 681 ? -28.818 -14.850 28.009 1.00 17.71 ? 681 THR A CG2 1 ATOM 5428 N N . PRO A 1 682 ? -25.339 -14.434 26.001 1.00 15.67 ? 682 PRO A N 1 ATOM 5429 C CA . PRO A 1 682 ? -24.946 -15.094 24.764 1.00 15.49 ? 682 PRO A CA 1 ATOM 5430 C C . PRO A 1 682 ? -25.538 -16.486 24.554 1.00 15.66 ? 682 PRO A C 1 ATOM 5431 O O . PRO A 1 682 ? -25.769 -17.226 25.516 1.00 16.05 ? 682 PRO A O 1 ATOM 5432 C CB . PRO A 1 682 ? -23.412 -15.226 24.895 1.00 15.64 ? 682 PRO A CB 1 ATOM 5433 C CG . PRO A 1 682 ? -23.183 -15.291 26.357 1.00 15.95 ? 682 PRO A CG 1 ATOM 5434 C CD . PRO A 1 682 ? -24.253 -14.424 26.992 1.00 16.05 ? 682 PRO A CD 1 ATOM 5435 N N . VAL A 1 683 ? -25.735 -16.844 23.287 1.00 16.62 ? 683 VAL A N 1 ATOM 5436 C CA . VAL A 1 683 ? -25.984 -18.228 22.898 1.00 17.12 ? 683 VAL A CA 1 ATOM 5437 C C . VAL A 1 683 ? -24.607 -18.890 22.884 1.00 18.35 ? 683 VAL A C 1 ATOM 5438 O O . VAL A 1 683 ? -23.677 -18.401 22.236 1.00 17.95 ? 683 VAL A O 1 ATOM 5439 C CB . VAL A 1 683 ? -26.668 -18.331 21.528 1.00 16.31 ? 683 VAL A CB 1 ATOM 5440 C CG1 . VAL A 1 683 ? -26.649 -19.774 21.034 1.00 17.05 ? 683 VAL A CG1 1 ATOM 5441 C CG2 . VAL A 1 683 ? -28.131 -17.847 21.635 1.00 18.43 ? 683 VAL A CG2 1 ATOM 5442 N N . LEU A 1 684 ? -24.488 -19.981 23.626 1.00 18.98 ? 684 LEU A N 1 ATOM 5443 C CA . LEU A 1 684 ? -23.205 -20.593 23.877 1.00 20.84 ? 684 LEU A CA 1 ATOM 5444 C C . LEU A 1 684 ? -23.138 -22.031 23.379 1.00 22.21 ? 684 LEU A C 1 ATOM 5445 O O . LEU A 1 684 ? -22.106 -22.696 23.548 1.00 22.34 ? 684 LEU A O 1 ATOM 5446 C CB . LEU A 1 684 ? -22.922 -20.555 25.377 1.00 19.99 ? 684 LEU A CB 1 ATOM 5447 C CG . LEU A 1 684 ? -22.675 -19.134 25.854 1.00 19.27 ? 684 LEU A CG 1 ATOM 5448 C CD1 . LEU A 1 684 ? -22.658 -19.082 27.345 1.00 18.66 ? 684 LEU A CD1 1 ATOM 5449 C CD2 . LEU A 1 684 ? -21.387 -18.534 25.278 1.00 16.14 ? 684 LEU A CD2 1 ATOM 5450 N N . ASP A 1 685 ? -24.241 -22.497 22.785 1.00 22.99 ? 685 ASP A N 1 ATOM 5451 C CA . ASP A 1 685 ? -24.383 -23.906 22.359 1.00 24.34 ? 685 ASP A CA 1 ATOM 5452 C C . ASP A 1 685 ? -24.560 -24.064 20.845 1.00 23.99 ? 685 ASP A C 1 ATOM 5453 O O . ASP A 1 685 ? -25.359 -23.347 20.249 1.00 22.56 ? 685 ASP A O 1 ATOM 5454 C CB . ASP A 1 685 ? -25.558 -24.530 23.096 1.00 25.29 ? 685 ASP A CB 1 ATOM 5455 C CG . ASP A 1 685 ? -25.333 -24.580 24.581 1.00 28.69 ? 685 ASP A CG 1 ATOM 5456 O OD1 . ASP A 1 685 ? -24.297 -25.140 24.996 1.00 32.49 ? 685 ASP A OD1 1 ATOM 5457 O OD2 . ASP A 1 685 ? -26.188 -24.064 25.336 1.00 33.11 ? 685 ASP A OD2 1 ATOM 5458 N N . GLU A 1 686 ? -23.799 -24.984 20.237 1.00 24.84 ? 686 GLU A N 1 ATOM 5459 C CA . GLU A 1 686 ? -23.841 -25.233 18.781 1.00 25.93 ? 686 GLU A CA 1 ATOM 5460 C C . GLU A 1 686 ? -25.246 -25.582 18.315 1.00 26.07 ? 686 GLU A C 1 ATOM 5461 O O . GLU A 1 686 ? -25.891 -26.449 18.893 1.00 26.15 ? 686 GLU A O 1 ATOM 5462 C CB . GLU A 1 686 ? -22.884 -26.356 18.363 1.00 26.00 ? 686 GLU A CB 1 ATOM 5463 C CG . GLU A 1 686 ? -22.656 -26.460 16.834 1.00 27.83 ? 686 GLU A CG 1 ATOM 5464 C CD . GLU A 1 686 ? -21.652 -27.555 16.406 1.00 28.64 ? 686 GLU A CD 1 ATOM 5465 O OE1 . GLU A 1 686 ? -20.843 -27.990 17.247 1.00 30.14 ? 686 GLU A OE1 1 ATOM 5466 O OE2 . GLU A 1 686 ? -21.684 -27.992 15.219 1.00 32.50 ? 686 GLU A OE2 1 ATOM 5467 N N . GLY A 1 687 ? -25.709 -24.901 17.271 1.00 26.35 ? 687 GLY A N 1 ATOM 5468 C CA . GLY A 1 687 ? -27.005 -25.206 16.667 1.00 27.14 ? 687 GLY A CA 1 ATOM 5469 C C . GLY A 1 687 ? -28.126 -24.443 17.322 1.00 27.36 ? 687 GLY A C 1 ATOM 5470 O O . GLY A 1 687 ? -29.261 -24.511 16.868 1.00 28.05 ? 687 GLY A O 1 ATOM 5471 N N . ALA A 1 688 ? -27.804 -23.709 18.389 1.00 27.09 ? 688 ALA A N 1 ATOM 5472 C CA . ALA A 1 688 ? -28.819 -23.078 19.233 1.00 26.80 ? 688 ALA A CA 1 ATOM 5473 C C . ALA A 1 688 ? -29.350 -21.724 18.749 1.00 26.70 ? 688 ALA A C 1 ATOM 5474 O O . ALA A 1 688 ? -28.599 -20.870 18.266 1.00 25.16 ? 688 ALA A O 1 ATOM 5475 C CB . ALA A 1 688 ? -28.330 -22.991 20.706 1.00 26.52 ? 688 ALA A CB 1 ATOM 5476 N N . GLU A 1 689 ? -30.665 -21.545 18.878 1.00 27.19 ? 689 GLU A N 1 ATOM 5477 C CA . GLU A 1 689 ? -31.292 -20.257 18.641 1.00 29.12 ? 689 GLU A CA 1 ATOM 5478 C C . GLU A 1 689 ? -32.144 -19.870 19.867 1.00 28.79 ? 689 GLU A C 1 ATOM 5479 O O . GLU A 1 689 ? -33.126 -19.112 19.795 1.00 27.60 ? 689 GLU A O 1 ATOM 5480 C CB . GLU A 1 689 ? -32.052 -20.231 17.306 1.00 29.75 ? 689 GLU A CB 1 ATOM 5481 C CG . GLU A 1 689 ? -31.131 -20.177 16.049 1.00 30.96 ? 689 GLU A CG 1 ATOM 5482 C CD . GLU A 1 689 ? -31.906 -20.011 14.727 1.00 33.13 ? 689 GLU A CD 1 ATOM 5483 O OE1 . GLU A 1 689 ? -32.738 -20.902 14.421 1.00 36.31 ? 689 GLU A OE1 1 ATOM 5484 O OE2 . GLU A 1 689 ? -31.661 -19.009 13.984 1.00 37.21 ? 689 GLU A OE2 1 ATOM 5485 N N . LYS A 1 690 ? -31.676 -20.381 20.998 1.00 28.92 ? 690 LYS A N 1 ATOM 5486 C CA . LYS A 1 690 ? -32.281 -20.246 22.299 1.00 30.07 ? 690 LYS A CA 1 ATOM 5487 C C . LYS A 1 690 ? -31.139 -20.269 23.308 1.00 30.35 ? 690 LYS A C 1 ATOM 5488 O O . LYS A 1 690 ? -30.110 -20.913 23.088 1.00 29.82 ? 690 LYS A O 1 ATOM 5489 C CB . LYS A 1 690 ? -33.180 -21.442 22.603 1.00 30.34 ? 690 LYS A CB 1 ATOM 5490 C CG . LYS A 1 690 ? -34.641 -21.314 22.154 1.00 33.40 ? 690 LYS A CG 1 ATOM 5491 C CD . LYS A 1 690 ? -35.305 -22.671 22.270 1.00 35.05 ? 690 LYS A CD 1 ATOM 5492 C CE . LYS A 1 690 ? -36.661 -22.718 21.576 1.00 39.12 ? 690 LYS A CE 1 ATOM 5493 N NZ . LYS A 1 690 ? -37.223 -24.119 21.572 1.00 38.30 ? 690 LYS A NZ 1 ATOM 5494 N N . VAL A 1 691 ? -31.322 -19.575 24.423 1.00 30.02 ? 691 VAL A N 1 ATOM 5495 C CA . VAL A 1 691 ? -30.406 -19.752 25.527 1.00 30.34 ? 691 VAL A CA 1 ATOM 5496 C C . VAL A 1 691 ? -31.243 -19.913 26.798 1.00 29.74 ? 691 VAL A C 1 ATOM 5497 O O . VAL A 1 691 ? -32.240 -19.201 26.991 1.00 29.10 ? 691 VAL A O 1 ATOM 5498 C CB . VAL A 1 691 ? -29.401 -18.592 25.593 1.00 29.91 ? 691 VAL A CB 1 ATOM 5499 C CG1 . VAL A 1 691 ? -29.892 -17.505 26.499 1.00 31.73 ? 691 VAL A CG1 1 ATOM 5500 C CG2 . VAL A 1 691 ? -28.061 -19.078 26.061 1.00 32.55 ? 691 VAL A CG2 1 ATOM 5501 N N . MET A 1 692 ? -30.871 -20.891 27.618 1.00 29.79 ? 692 MET A N 1 ATOM 5502 C CA . MET A 1 692 ? -31.424 -21.024 28.971 1.00 29.70 ? 692 MET A CA 1 ATOM 5503 C C . MET A 1 692 ? -30.686 -20.011 29.847 1.00 27.91 ? 692 MET A C 1 ATOM 5504 O O . MET A 1 692 ? -29.485 -20.136 30.080 1.00 28.16 ? 692 MET A O 1 ATOM 5505 C CB . MET A 1 692 ? -31.293 -22.458 29.505 1.00 31.31 ? 692 MET A CB 1 ATOM 5506 C CG . MET A 1 692 ? -32.386 -23.422 29.007 1.00 35.01 ? 692 MET A CG 1 ATOM 5507 S SD . MET A 1 692 ? -34.024 -23.134 29.776 1.00 44.92 ? 692 MET A SD 1 ATOM 5508 C CE . MET A 1 692 ? -35.109 -23.896 28.580 1.00 39.55 ? 692 MET A CE 1 ATOM 5509 N N . ALA A 1 693 ? -31.417 -19.005 30.306 1.00 25.63 ? 693 ALA A N 1 ATOM 5510 C CA . ALA A 1 693 ? -30.841 -17.825 30.936 1.00 24.25 ? 693 ALA A CA 1 ATOM 5511 C C . ALA A 1 693 ? -31.478 -17.532 32.268 1.00 23.59 ? 693 ALA A C 1 ATOM 5512 O O . ALA A 1 693 ? -32.628 -17.868 32.494 1.00 23.76 ? 693 ALA A O 1 ATOM 5513 C CB . ALA A 1 693 ? -30.992 -16.607 30.022 1.00 23.75 ? 693 ALA A CB 1 ATOM 5514 N N . TYR A 1 694 ? -30.728 -16.877 33.148 1.00 22.26 ? 694 TYR A N 1 ATOM 5515 C CA . TYR A 1 694 ? -31.302 -16.379 34.366 1.00 20.82 ? 694 TYR A CA 1 ATOM 5516 C C . TYR A 1 694 ? -31.618 -14.879 34.295 1.00 20.19 ? 694 TYR A C 1 ATOM 5517 O O . TYR A 1 694 ? -30.779 -14.051 33.926 1.00 20.64 ? 694 TYR A O 1 ATOM 5518 C CB . TYR A 1 694 ? -30.501 -16.814 35.610 1.00 20.89 ? 694 TYR A CB 1 ATOM 5519 C CG . TYR A 1 694 ? -31.290 -16.576 36.866 1.00 20.51 ? 694 TYR A CG 1 ATOM 5520 C CD1 . TYR A 1 694 ? -32.397 -17.374 37.186 1.00 21.97 ? 694 TYR A CD1 1 ATOM 5521 C CD2 . TYR A 1 694 ? -30.993 -15.513 37.688 1.00 20.49 ? 694 TYR A CD2 1 ATOM 5522 C CE1 . TYR A 1 694 ? -33.152 -17.115 38.325 1.00 19.63 ? 694 TYR A CE1 1 ATOM 5523 C CE2 . TYR A 1 694 ? -31.736 -15.253 38.824 1.00 19.63 ? 694 TYR A CE2 1 ATOM 5524 C CZ . TYR A 1 694 ? -32.798 -16.061 39.137 1.00 21.08 ? 694 TYR A CZ 1 ATOM 5525 O OH . TYR A 1 694 ? -33.509 -15.767 40.267 1.00 20.38 ? 694 TYR A OH 1 ATOM 5526 N N . VAL A 1 695 ? -32.869 -14.540 34.586 1.00 18.57 ? 695 VAL A N 1 ATOM 5527 C CA . VAL A 1 695 ? -33.253 -13.139 34.687 1.00 18.15 ? 695 VAL A CA 1 ATOM 5528 C C . VAL A 1 695 ? -33.357 -12.712 36.166 1.00 18.19 ? 695 VAL A C 1 ATOM 5529 O O . VAL A 1 695 ? -34.272 -13.132 36.876 1.00 18.05 ? 695 VAL A O 1 ATOM 5530 C CB . VAL A 1 695 ? -34.558 -12.832 33.922 1.00 17.84 ? 695 VAL A CB 1 ATOM 5531 C CG1 . VAL A 1 695 ? -34.758 -11.369 33.844 1.00 16.04 ? 695 VAL A CG1 1 ATOM 5532 C CG2 . VAL A 1 695 ? -34.531 -13.436 32.497 1.00 17.64 ? 695 VAL A CG2 1 ATOM 5533 N N . PRO A 1 696 ? -32.392 -11.911 36.643 1.00 18.37 ? 696 PRO A N 1 ATOM 5534 C CA . PRO A 1 696 ? -32.382 -11.442 38.024 1.00 18.82 ? 696 PRO A CA 1 ATOM 5535 C C . PRO A 1 696 ? -33.602 -10.645 38.494 1.00 20.30 ? 696 PRO A C 1 ATOM 5536 O O . PRO A 1 696 ? -34.484 -10.258 37.686 1.00 19.70 ? 696 PRO A O 1 ATOM 5537 C CB . PRO A 1 696 ? -31.114 -10.590 38.077 1.00 18.94 ? 696 PRO A CB 1 ATOM 5538 C CG . PRO A 1 696 ? -30.223 -11.219 37.057 1.00 18.58 ? 696 PRO A CG 1 ATOM 5539 C CD . PRO A 1 696 ? -31.185 -11.455 35.930 1.00 18.78 ? 696 PRO A CD 1 ATOM 5540 N N . ASP A 1 697 ? -33.641 -10.434 39.810 1.00 20.66 ? 697 ASP A N 1 ATOM 5541 C CA . ASP A 1 697 ? -34.699 -9.699 40.497 1.00 21.06 ? 697 ASP A CA 1 ATOM 5542 C C . ASP A 1 697 ? -34.634 -8.189 40.261 1.00 20.97 ? 697 ASP A C 1 ATOM 5543 O O . ASP A 1 697 ? -34.154 -7.424 41.110 1.00 21.31 ? 697 ASP A O 1 ATOM 5544 C CB . ASP A 1 697 ? -34.637 -10.019 41.993 1.00 21.62 ? 697 ASP A CB 1 ATOM 5545 C CG . ASP A 1 697 ? -35.905 -9.621 42.742 1.00 23.61 ? 697 ASP A CG 1 ATOM 5546 O OD1 . ASP A 1 697 ? -36.861 -9.100 42.122 1.00 24.46 ? 697 ASP A OD1 1 ATOM 5547 O OD2 . ASP A 1 697 ? -35.925 -9.811 43.974 1.00 25.87 ? 697 ASP A OD2 1 ATOM 5548 N N . ALA A 1 698 ? -35.139 -7.768 39.097 1.00 19.94 ? 698 ALA A N 1 ATOM 5549 C CA . ALA A 1 698 ? -35.138 -6.369 38.680 1.00 18.57 ? 698 ALA A CA 1 ATOM 5550 C C . ALA A 1 698 ? -36.086 -6.230 37.523 1.00 17.64 ? 698 ALA A C 1 ATOM 5551 O O . ALA A 1 698 ? -36.464 -7.208 36.898 1.00 18.53 ? 698 ALA A O 1 ATOM 5552 C CB . ALA A 1 698 ? -33.700 -5.916 38.228 1.00 17.95 ? 698 ALA A CB 1 ATOM 5553 N N . VAL A 1 699 ? -36.448 -5.003 37.221 1.00 17.86 ? 699 VAL A N 1 ATOM 5554 C CA . VAL A 1 699 ? -37.085 -4.673 35.951 1.00 18.41 ? 699 VAL A CA 1 ATOM 5555 C C . VAL A 1 699 ? -36.014 -4.719 34.860 1.00 17.72 ? 699 VAL A C 1 ATOM 5556 O O . VAL A 1 699 ? -34.977 -4.106 35.021 1.00 18.06 ? 699 VAL A O 1 ATOM 5557 C CB . VAL A 1 699 ? -37.647 -3.236 36.004 1.00 18.57 ? 699 VAL A CB 1 ATOM 5558 C CG1 . VAL A 1 699 ? -38.140 -2.812 34.626 1.00 19.81 ? 699 VAL A CG1 1 ATOM 5559 C CG2 . VAL A 1 699 ? -38.731 -3.144 37.047 1.00 20.01 ? 699 VAL A CG2 1 ATOM 5560 N N . TRP A 1 700 ? -36.258 -5.464 33.775 1.00 16.70 ? 700 TRP A N 1 ATOM 5561 C CA . TRP A 1 700 ? -35.358 -5.518 32.616 1.00 15.93 ? 700 TRP A CA 1 ATOM 5562 C C . TRP A 1 700 ? -36.081 -5.043 31.356 1.00 16.40 ? 700 TRP A C 1 ATOM 5563 O O . TRP A 1 700 ? -37.302 -5.281 31.195 1.00 15.48 ? 700 TRP A O 1 ATOM 5564 C CB . TRP A 1 700 ? -34.813 -6.931 32.410 1.00 15.42 ? 700 TRP A CB 1 ATOM 5565 C CG . TRP A 1 700 ? -33.969 -7.423 33.582 1.00 15.92 ? 700 TRP A CG 1 ATOM 5566 C CD1 . TRP A 1 700 ? -34.372 -8.243 34.598 1.00 16.26 ? 700 TRP A CD1 1 ATOM 5567 C CD2 . TRP A 1 700 ? -32.608 -7.088 33.855 1.00 15.78 ? 700 TRP A CD2 1 ATOM 5568 N NE1 . TRP A 1 700 ? -33.337 -8.454 35.472 1.00 16.87 ? 700 TRP A NE1 1 ATOM 5569 C CE2 . TRP A 1 700 ? -32.242 -7.753 35.039 1.00 16.01 ? 700 TRP A CE2 1 ATOM 5570 C CE3 . TRP A 1 700 ? -31.646 -6.315 33.189 1.00 14.61 ? 700 TRP A CE3 1 ATOM 5571 C CZ2 . TRP A 1 700 ? -30.956 -7.657 35.590 1.00 17.88 ? 700 TRP A CZ2 1 ATOM 5572 C CZ3 . TRP A 1 700 ? -30.376 -6.217 33.729 1.00 15.60 ? 700 TRP A CZ3 1 ATOM 5573 C CH2 . TRP A 1 700 ? -30.034 -6.887 34.919 1.00 17.06 ? 700 TRP A CH2 1 ATOM 5574 N N . TYR A 1 701 ? -35.342 -4.322 30.512 1.00 15.51 ? 701 TYR A N 1 ATOM 5575 C CA . TYR A 1 701 ? -35.798 -3.853 29.205 1.00 15.16 ? 701 TYR A CA 1 ATOM 5576 C C . TYR A 1 701 ? -34.906 -4.367 28.110 1.00 16.77 ? 701 TYR A C 1 ATOM 5577 O O . TYR A 1 701 ? -33.666 -4.288 28.197 1.00 16.31 ? 701 TYR A O 1 ATOM 5578 C CB . TYR A 1 701 ? -35.784 -2.332 29.129 1.00 13.94 ? 701 TYR A CB 1 ATOM 5579 C CG . TYR A 1 701 ? -36.573 -1.618 30.190 1.00 14.20 ? 701 TYR A CG 1 ATOM 5580 C CD1 . TYR A 1 701 ? -37.951 -1.397 30.022 1.00 14.90 ? 701 TYR A CD1 1 ATOM 5581 C CD2 . TYR A 1 701 ? -35.976 -1.190 31.369 1.00 14.62 ? 701 TYR A CD2 1 ATOM 5582 C CE1 . TYR A 1 701 ? -38.690 -0.717 30.990 1.00 13.46 ? 701 TYR A CE1 1 ATOM 5583 C CE2 . TYR A 1 701 ? -36.705 -0.541 32.343 1.00 14.02 ? 701 TYR A CE2 1 ATOM 5584 C CZ . TYR A 1 701 ? -38.089 -0.325 32.138 1.00 13.99 ? 701 TYR A CZ 1 ATOM 5585 O OH . TYR A 1 701 ? -38.843 0.337 33.072 1.00 12.36 ? 701 TYR A OH 1 ATOM 5586 N N . ASP A 1 702 ? -35.526 -4.875 27.057 1.00 17.76 ? 702 ASP A N 1 ATOM 5587 C CA . ASP A 1 702 ? -34.794 -5.212 25.854 1.00 19.09 ? 702 ASP A CA 1 ATOM 5588 C C . ASP A 1 702 ? -34.061 -3.980 25.319 1.00 19.40 ? 702 ASP A C 1 ATOM 5589 O O . ASP A 1 702 ? -34.669 -2.924 25.064 1.00 18.10 ? 702 ASP A O 1 ATOM 5590 C CB . ASP A 1 702 ? -35.738 -5.784 24.810 1.00 19.83 ? 702 ASP A CB 1 ATOM 5591 C CG . ASP A 1 702 ? -35.019 -6.235 23.557 1.00 23.17 ? 702 ASP A CG 1 ATOM 5592 O OD1 . ASP A 1 702 ? -34.740 -7.440 23.463 1.00 29.87 ? 702 ASP A OD1 1 ATOM 5593 O OD2 . ASP A 1 702 ? -34.721 -5.395 22.686 1.00 25.58 ? 702 ASP A OD2 1 ATOM 5594 N N . TYR A 1 703 ? -32.753 -4.127 25.118 1.00 18.90 ? 703 TYR A N 1 ATOM 5595 C CA . TYR A 1 703 ? -31.928 -2.996 24.727 1.00 19.29 ? 703 TYR A CA 1 ATOM 5596 C C . TYR A 1 703 ? -32.384 -2.346 23.419 1.00 20.10 ? 703 TYR A C 1 ATOM 5597 O O . TYR A 1 703 ? -32.490 -1.135 23.354 1.00 21.37 ? 703 TYR A O 1 ATOM 5598 C CB . TYR A 1 703 ? -30.429 -3.353 24.669 1.00 18.98 ? 703 TYR A CB 1 ATOM 5599 C CG . TYR A 1 703 ? -29.618 -2.221 24.108 1.00 19.51 ? 703 TYR A CG 1 ATOM 5600 C CD1 . TYR A 1 703 ? -29.108 -1.227 24.931 1.00 17.56 ? 703 TYR A CD1 1 ATOM 5601 C CD2 . TYR A 1 703 ? -29.405 -2.115 22.724 1.00 19.11 ? 703 TYR A CD2 1 ATOM 5602 C CE1 . TYR A 1 703 ? -28.372 -0.174 24.409 1.00 19.03 ? 703 TYR A CE1 1 ATOM 5603 C CE2 . TYR A 1 703 ? -28.697 -1.058 22.194 1.00 18.98 ? 703 TYR A CE2 1 ATOM 5604 C CZ . TYR A 1 703 ? -28.192 -0.091 23.040 1.00 19.03 ? 703 TYR A CZ 1 ATOM 5605 O OH . TYR A 1 703 ? -27.485 0.959 22.522 1.00 21.60 ? 703 TYR A OH 1 ATOM 5606 N N . GLU A 1 704 ? -32.653 -3.135 22.388 1.00 21.26 ? 704 GLU A N 1 ATOM 5607 C CA . GLU A 1 704 ? -32.988 -2.585 21.063 1.00 22.89 ? 704 GLU A CA 1 ATOM 5608 C C . GLU A 1 704 ? -34.407 -2.029 20.929 1.00 22.87 ? 704 GLU A C 1 ATOM 5609 O O . GLU A 1 704 ? -34.597 -0.949 20.396 1.00 23.23 ? 704 GLU A O 1 ATOM 5610 C CB . GLU A 1 704 ? -32.735 -3.628 19.984 1.00 23.54 ? 704 GLU A CB 1 ATOM 5611 C CG . GLU A 1 704 ? -31.255 -4.011 19.919 1.00 27.15 ? 704 GLU A CG 1 ATOM 5612 C CD . GLU A 1 704 ? -30.825 -4.317 18.519 1.00 30.16 ? 704 GLU A CD 1 ATOM 5613 O OE1 . GLU A 1 704 ? -30.945 -3.418 17.633 1.00 30.40 ? 704 GLU A OE1 1 ATOM 5614 O OE2 . GLU A 1 704 ? -30.370 -5.461 18.322 1.00 29.76 ? 704 GLU A OE2 1 ATOM 5615 N N . THR A 1 705 ? -35.396 -2.756 21.429 1.00 23.57 ? 705 THR A N 1 ATOM 5616 C CA . THR A 1 705 ? -36.783 -2.279 21.349 1.00 23.58 ? 705 THR A CA 1 ATOM 5617 C C . THR A 1 705 ? -37.133 -1.335 22.497 1.00 23.20 ? 705 THR A C 1 ATOM 5618 O O . THR A 1 705 ? -37.915 -0.408 22.321 1.00 24.05 ? 705 THR A O 1 ATOM 5619 C CB . THR A 1 705 ? -37.766 -3.449 21.284 1.00 23.62 ? 705 THR A CB 1 ATOM 5620 O OG1 . THR A 1 705 ? -37.697 -4.196 22.501 1.00 24.44 ? 705 THR A OG1 1 ATOM 5621 C CG2 . THR A 1 705 ? -37.415 -4.370 20.119 1.00 24.99 ? 705 THR A CG2 1 ATOM 5622 N N . GLY A 1 706 ? -36.537 -1.556 23.668 1.00 22.53 ? 706 GLY A N 1 ATOM 5623 C CA . GLY A 1 706 ? -36.851 -0.772 24.843 1.00 22.10 ? 706 GLY A CA 1 ATOM 5624 C C . GLY A 1 706 ? -38.017 -1.358 25.634 1.00 22.50 ? 706 GLY A C 1 ATOM 5625 O O . GLY A 1 706 ? -38.383 -0.820 26.665 1.00 22.05 ? 706 GLY A O 1 ATOM 5626 N N . SER A 1 707 ? -38.597 -2.457 25.150 1.00 22.76 ? 707 SER A N 1 ATOM 5627 C CA . SER A 1 707 ? -39.734 -3.089 25.825 1.00 23.17 ? 707 SER A CA 1 ATOM 5628 C C . SER A 1 707 ? -39.367 -3.832 27.095 1.00 23.42 ? 707 SER A C 1 ATOM 5629 O O . SER A 1 707 ? -38.332 -4.526 27.167 1.00 22.31 ? 707 SER A O 1 ATOM 5630 C CB . SER A 1 707 ? -40.463 -4.036 24.895 1.00 23.48 ? 707 SER A CB 1 ATOM 5631 O OG . SER A 1 707 ? -39.698 -5.186 24.673 1.00 27.79 ? 707 SER A OG 1 ATOM 5632 N N . GLN A 1 708 ? -40.230 -3.690 28.094 1.00 23.65 ? 708 GLN A N 1 ATOM 5633 C CA . GLN A 1 708 ? -40.038 -4.343 29.392 1.00 25.07 ? 708 GLN A CA 1 ATOM 5634 C C . GLN A 1 708 ? -40.370 -5.826 29.305 1.00 25.73 ? 708 GLN A C 1 ATOM 5635 O O . GLN A 1 708 ? -41.507 -6.214 28.986 1.00 26.08 ? 708 GLN A O 1 ATOM 5636 C CB . GLN A 1 708 ? -40.881 -3.655 30.467 1.00 25.57 ? 708 GLN A CB 1 ATOM 5637 C CG . GLN A 1 708 ? -40.553 -4.051 31.903 1.00 24.73 ? 708 GLN A CG 1 ATOM 5638 C CD . GLN A 1 708 ? -41.616 -3.547 32.896 1.00 26.04 ? 708 GLN A CD 1 ATOM 5639 O OE1 . GLN A 1 708 ? -42.176 -2.465 32.731 1.00 25.03 ? 708 GLN A OE1 1 ATOM 5640 N NE2 . GLN A 1 708 ? -41.866 -4.330 33.946 1.00 26.97 ? 708 GLN A NE2 1 ATOM 5641 N N . VAL A 1 709 ? -39.375 -6.660 29.585 1.00 25.42 ? 709 VAL A N 1 ATOM 5642 C CA . VAL A 1 709 ? -39.587 -8.097 29.627 1.00 26.25 ? 709 VAL A CA 1 ATOM 5643 C C . VAL A 1 709 ? -40.566 -8.424 30.753 1.00 26.83 ? 709 VAL A C 1 ATOM 5644 O O . VAL A 1 709 ? -40.671 -7.678 31.727 1.00 25.73 ? 709 VAL A O 1 ATOM 5645 C CB . VAL A 1 709 ? -38.269 -8.894 29.774 1.00 26.23 ? 709 VAL A CB 1 ATOM 5646 C CG1 . VAL A 1 709 ? -37.283 -8.439 28.721 1.00 25.61 ? 709 VAL A CG1 1 ATOM 5647 C CG2 . VAL A 1 709 ? -37.661 -8.753 31.188 1.00 24.60 ? 709 VAL A CG2 1 ATOM 5648 N N . ARG A 1 710 ? -41.304 -9.519 30.613 1.00 28.18 ? 710 ARG A N 1 ATOM 5649 C CA . ARG A 1 710 ? -42.199 -9.912 31.703 1.00 30.03 ? 710 ARG A CA 1 ATOM 5650 C C . ARG A 1 710 ? -41.465 -10.785 32.733 1.00 29.55 ? 710 ARG A C 1 ATOM 5651 O O . ARG A 1 710 ? -41.897 -10.923 33.887 1.00 30.89 ? 710 ARG A O 1 ATOM 5652 C CB . ARG A 1 710 ? -43.498 -10.534 31.178 1.00 31.82 ? 710 ARG A CB 1 ATOM 5653 C CG . ARG A 1 710 ? -44.531 -9.506 30.624 1.00 34.42 ? 710 ARG A CG 1 ATOM 5654 C CD . ARG A 1 710 ? -44.744 -8.288 31.563 1.00 40.40 ? 710 ARG A CD 1 ATOM 5655 N NE . ARG A 1 710 ? -45.714 -7.303 31.048 1.00 42.70 ? 710 ARG A NE 1 ATOM 5656 C CZ . ARG A 1 710 ? -45.697 -5.992 31.322 1.00 46.42 ? 710 ARG A CZ 1 ATOM 5657 N NH1 . ARG A 1 710 ? -44.742 -5.470 32.092 1.00 47.71 ? 710 ARG A NH1 1 ATOM 5658 N NH2 . ARG A 1 710 ? -46.637 -5.192 30.815 1.00 46.48 ? 710 ARG A NH2 1 ATOM 5659 N N . TRP A 1 711 ? -40.319 -11.320 32.343 1.00 28.17 ? 711 TRP A N 1 ATOM 5660 C CA . TRP A 1 711 ? -39.513 -12.107 33.278 1.00 26.91 ? 711 TRP A CA 1 ATOM 5661 C C . TRP A 1 711 ? -38.937 -11.263 34.407 1.00 25.78 ? 711 TRP A C 1 ATOM 5662 O O . TRP A 1 711 ? -38.490 -10.147 34.185 1.00 25.83 ? 711 TRP A O 1 ATOM 5663 C CB . TRP A 1 711 ? -38.384 -12.836 32.564 1.00 26.82 ? 711 TRP A CB 1 ATOM 5664 C CG . TRP A 1 711 ? -38.717 -13.417 31.223 1.00 27.61 ? 711 TRP A CG 1 ATOM 5665 C CD1 . TRP A 1 711 ? -39.745 -14.275 30.913 1.00 27.77 ? 711 TRP A CD1 1 ATOM 5666 C CD2 . TRP A 1 711 ? -37.972 -13.231 30.012 1.00 27.85 ? 711 TRP A CD2 1 ATOM 5667 N NE1 . TRP A 1 711 ? -39.692 -14.599 29.583 1.00 28.33 ? 711 TRP A NE1 1 ATOM 5668 C CE2 . TRP A 1 711 ? -38.611 -13.979 29.011 1.00 28.73 ? 711 TRP A CE2 1 ATOM 5669 C CE3 . TRP A 1 711 ? -36.832 -12.483 29.677 1.00 27.84 ? 711 TRP A CE3 1 ATOM 5670 C CZ2 . TRP A 1 711 ? -38.148 -14.008 27.688 1.00 29.24 ? 711 TRP A CZ2 1 ATOM 5671 C CZ3 . TRP A 1 711 ? -36.374 -12.516 28.375 1.00 28.33 ? 711 TRP A CZ3 1 ATOM 5672 C CH2 . TRP A 1 711 ? -37.036 -13.263 27.391 1.00 27.87 ? 711 TRP A CH2 1 ATOM 5673 N N . ARG A 1 712 ? -38.949 -11.826 35.616 1.00 25.05 ? 712 ARG A N 1 ATOM 5674 C CA . ARG A 1 712 ? -38.275 -11.276 36.790 1.00 24.48 ? 712 ARG A CA 1 ATOM 5675 C C . ARG A 1 712 ? -37.964 -12.406 37.789 1.00 23.82 ? 712 ARG A C 1 ATOM 5676 O O . ARG A 1 712 ? -38.863 -13.156 38.211 1.00 22.66 ? 712 ARG A O 1 ATOM 5677 C CB . ARG A 1 712 ? -39.139 -10.196 37.468 1.00 25.77 ? 712 ARG A CB 1 ATOM 5678 C CG . ARG A 1 712 ? -38.465 -9.580 38.677 1.00 24.91 ? 712 ARG A CG 1 ATOM 5679 C CD . ARG A 1 712 ? -39.076 -8.278 39.053 1.00 29.09 ? 712 ARG A CD 1 ATOM 5680 N NE . ARG A 1 712 ? -38.305 -7.665 40.125 1.00 29.02 ? 712 ARG A NE 1 ATOM 5681 C CZ . ARG A 1 712 ? -38.354 -6.381 40.447 1.00 30.53 ? 712 ARG A CZ 1 ATOM 5682 N NH1 . ARG A 1 712 ? -39.133 -5.558 39.766 1.00 32.33 ? 712 ARG A NH1 1 ATOM 5683 N NH2 . ARG A 1 712 ? -37.604 -5.916 41.440 1.00 30.68 ? 712 ARG A NH2 1 ATOM 5684 N N . LYS A 1 713 ? -36.686 -12.535 38.152 1.00 22.34 ? 713 LYS A N 1 ATOM 5685 C CA . LYS A 1 713 ? -36.219 -13.532 39.138 1.00 21.87 ? 713 LYS A CA 1 ATOM 5686 C C . LYS A 1 713 ? -36.592 -14.973 38.767 1.00 22.17 ? 713 LYS A C 1 ATOM 5687 O O . LYS A 1 713 ? -37.259 -15.684 39.519 1.00 22.16 ? 713 LYS A O 1 ATOM 5688 C CB . LYS A 1 713 ? -36.656 -13.163 40.573 1.00 21.07 ? 713 LYS A CB 1 ATOM 5689 C CG . LYS A 1 713 ? -35.760 -13.738 41.703 1.00 22.18 ? 713 LYS A CG 1 ATOM 5690 C CD . LYS A 1 713 ? -36.308 -13.430 43.122 1.00 20.73 ? 713 LYS A CD 1 ATOM 5691 C CE . LYS A 1 713 ? -35.411 -14.051 44.197 1.00 21.79 ? 713 LYS A CE 1 ATOM 5692 N NZ . LYS A 1 713 ? -35.722 -13.679 45.610 1.00 21.52 ? 713 LYS A NZ 1 ATOM 5693 N N . GLN A 1 714 ? -36.121 -15.420 37.613 1.00 22.20 ? 714 GLN A N 1 ATOM 5694 C CA . GLN A 1 714 ? -36.495 -16.740 37.118 1.00 22.49 ? 714 GLN A CA 1 ATOM 5695 C C . GLN A 1 714 ? -35.603 -17.161 35.972 1.00 22.97 ? 714 GLN A C 1 ATOM 5696 O O . GLN A 1 714 ? -35.059 -16.300 35.281 1.00 22.47 ? 714 GLN A O 1 ATOM 5697 C CB . GLN A 1 714 ? -37.952 -16.703 36.617 1.00 22.04 ? 714 GLN A CB 1 ATOM 5698 C CG . GLN A 1 714 ? -38.218 -15.680 35.511 1.00 20.37 ? 714 GLN A CG 1 ATOM 5699 C CD . GLN A 1 714 ? -39.709 -15.625 35.166 1.00 22.49 ? 714 GLN A CD 1 ATOM 5700 O OE1 . GLN A 1 714 ? -40.257 -16.587 34.647 1.00 25.37 ? 714 GLN A OE1 1 ATOM 5701 N NE2 . GLN A 1 714 ? -40.363 -14.525 35.499 1.00 20.95 ? 714 GLN A NE2 1 ATOM 5702 N N . LYS A 1 715 ? -35.481 -18.472 35.767 1.00 23.87 ? 715 LYS A N 1 ATOM 5703 C CA . LYS A 1 715 ? -34.850 -19.036 34.571 1.00 26.35 ? 715 LYS A CA 1 ATOM 5704 C C . LYS A 1 715 ? -35.802 -18.937 33.399 1.00 26.86 ? 715 LYS A C 1 ATOM 5705 O O . LYS A 1 715 ? -37.007 -19.140 33.559 1.00 27.65 ? 715 LYS A O 1 ATOM 5706 C CB . LYS A 1 715 ? -34.471 -20.502 34.779 1.00 26.58 ? 715 LYS A CB 1 ATOM 5707 C CG . LYS A 1 715 ? -33.466 -20.712 35.872 1.00 29.90 ? 715 LYS A CG 1 ATOM 5708 C CD . LYS A 1 715 ? -33.643 -22.074 36.546 1.00 33.51 ? 715 LYS A CD 1 ATOM 5709 C CE . LYS A 1 715 ? -32.592 -22.247 37.637 1.00 34.59 ? 715 LYS A CE 1 ATOM 5710 N NZ . LYS A 1 715 ? -32.369 -20.968 38.398 1.00 32.38 ? 715 LYS A NZ 1 ATOM 5711 N N . VAL A 1 716 ? -35.268 -18.603 32.231 1.00 27.52 ? 716 VAL A N 1 ATOM 5712 C CA . VAL A 1 716 ? -36.070 -18.468 31.024 1.00 28.15 ? 716 VAL A CA 1 ATOM 5713 C C . VAL A 1 716 ? -35.383 -19.117 29.834 1.00 28.55 ? 716 VAL A C 1 ATOM 5714 O O . VAL A 1 716 ? -34.159 -19.311 29.829 1.00 29.40 ? 716 VAL A O 1 ATOM 5715 C CB . VAL A 1 716 ? -36.400 -16.967 30.689 1.00 28.50 ? 716 VAL A CB 1 ATOM 5716 C CG1 . VAL A 1 716 ? -37.045 -16.269 31.869 1.00 28.88 ? 716 VAL A CG1 1 ATOM 5717 C CG2 . VAL A 1 716 ? -35.173 -16.203 30.260 1.00 27.70 ? 716 VAL A CG2 1 ATOM 5718 N N . GLU A 1 717 ? -36.172 -19.444 28.821 1.00 29.01 ? 717 GLU A N 1 ATOM 5719 C CA . GLU A 1 717 ? -35.649 -19.812 27.515 1.00 30.51 ? 717 GLU A CA 1 ATOM 5720 C C . GLU A 1 717 ? -35.698 -18.544 26.668 1.00 29.06 ? 717 GLU A C 1 ATOM 5721 O O . GLU A 1 717 ? -36.767 -18.158 26.192 1.00 28.86 ? 717 GLU A O 1 ATOM 5722 C CB . GLU A 1 717 ? -36.500 -20.922 26.898 1.00 30.34 ? 717 GLU A CB 1 ATOM 5723 C CG . GLU A 1 717 ? -35.812 -21.742 25.829 1.00 33.68 ? 717 GLU A CG 1 ATOM 5724 C CD . GLU A 1 717 ? -36.650 -22.933 25.372 1.00 34.81 ? 717 GLU A CD 1 ATOM 5725 O OE1 . GLU A 1 717 ? -37.858 -22.746 25.050 1.00 41.72 ? 717 GLU A OE1 1 ATOM 5726 O OE2 . GLU A 1 717 ? -36.099 -24.059 25.316 1.00 40.39 ? 717 GLU A OE2 1 ATOM 5727 N N . MET A 1 718 ? -34.553 -17.865 26.534 1.00 27.30 ? 718 MET A N 1 ATOM 5728 C CA . MET A 1 718 ? -34.488 -16.622 25.764 1.00 26.86 ? 718 MET A CA 1 ATOM 5729 C C . MET A 1 718 ? -34.348 -16.985 24.291 1.00 26.27 ? 718 MET A C 1 ATOM 5730 O O . MET A 1 718 ? -33.456 -17.758 23.937 1.00 26.05 ? 718 MET A O 1 ATOM 5731 C CB . MET A 1 718 ? -33.293 -15.776 26.216 1.00 26.60 ? 718 MET A CB 1 ATOM 5732 C CG . MET A 1 718 ? -33.398 -14.306 25.907 1.00 27.10 ? 718 MET A CG 1 ATOM 5733 S SD . MET A 1 718 ? -32.087 -13.360 26.714 1.00 27.63 ? 718 MET A SD 1 ATOM 5734 C CE . MET A 1 718 ? -32.725 -13.127 28.381 1.00 24.71 ? 718 MET A CE 1 ATOM 5735 N N . GLU A 1 719 ? -35.222 -16.444 23.441 1.00 25.51 ? 719 GLU A N 1 ATOM 5736 C CA . GLU A 1 719 ? -35.186 -16.762 22.004 1.00 25.81 ? 719 GLU A CA 1 ATOM 5737 C C . GLU A 1 719 ? -34.123 -15.885 21.377 1.00 23.99 ? 719 GLU A C 1 ATOM 5738 O O . GLU A 1 719 ? -34.244 -14.670 21.369 1.00 24.14 ? 719 GLU A O 1 ATOM 5739 C CB . GLU A 1 719 ? -36.515 -16.461 21.309 1.00 26.38 ? 719 GLU A CB 1 ATOM 5740 C CG . GLU A 1 719 ? -37.742 -16.948 22.046 1.00 31.70 ? 719 GLU A CG 1 ATOM 5741 C CD . GLU A 1 719 ? -38.218 -18.290 21.572 1.00 39.69 ? 719 GLU A CD 1 ATOM 5742 O OE1 . GLU A 1 719 ? -37.395 -19.235 21.530 1.00 42.27 ? 719 GLU A OE1 1 ATOM 5743 O OE2 . GLU A 1 719 ? -39.434 -18.398 21.251 1.00 43.82 ? 719 GLU A OE2 1 ATOM 5744 N N . LEU A 1 720 ? -33.077 -16.504 20.869 1.00 23.61 ? 720 LEU A N 1 ATOM 5745 C CA . LEU A 1 720 ? -31.973 -15.744 20.289 1.00 22.91 ? 720 LEU A CA 1 ATOM 5746 C C . LEU A 1 720 ? -31.560 -16.340 18.955 1.00 22.02 ? 720 LEU A C 1 ATOM 5747 O O . LEU A 1 720 ? -30.679 -17.202 18.900 1.00 21.72 ? 720 LEU A O 1 ATOM 5748 C CB . LEU A 1 720 ? -30.796 -15.636 21.254 1.00 23.09 ? 720 LEU A CB 1 ATOM 5749 C CG . LEU A 1 720 ? -31.077 -14.908 22.565 1.00 24.21 ? 720 LEU A CG 1 ATOM 5750 C CD1 . LEU A 1 720 ? -29.921 -15.128 23.545 1.00 22.81 ? 720 LEU A CD1 1 ATOM 5751 C CD2 . LEU A 1 720 ? -31.352 -13.427 22.331 1.00 23.25 ? 720 LEU A CD2 1 ATOM 5752 N N . PRO A 1 721 ? -32.202 -15.866 17.871 1.00 21.56 ? 721 PRO A N 1 ATOM 5753 C CA . PRO A 1 721 ? -31.935 -16.333 16.518 1.00 21.28 ? 721 PRO A CA 1 ATOM 5754 C C . PRO A 1 721 ? -30.465 -16.062 16.174 1.00 20.58 ? 721 PRO A C 1 ATOM 5755 O O . PRO A 1 721 ? -29.778 -15.420 16.962 1.00 19.18 ? 721 PRO A O 1 ATOM 5756 C CB . PRO A 1 721 ? -32.862 -15.468 15.661 1.00 21.95 ? 721 PRO A CB 1 ATOM 5757 C CG . PRO A 1 721 ? -33.941 -15.005 16.573 1.00 22.03 ? 721 PRO A CG 1 ATOM 5758 C CD . PRO A 1 721 ? -33.267 -14.843 17.905 1.00 22.54 ? 721 PRO A CD 1 ATOM 5759 N N . GLY A 1 722 ? -30.003 -16.539 15.017 1.00 20.08 ? 722 GLY A N 1 ATOM 5760 C CA . GLY A 1 722 ? -28.588 -16.450 14.654 1.00 20.95 ? 722 GLY A CA 1 ATOM 5761 C C . GLY A 1 722 ? -28.014 -15.057 14.624 1.00 20.62 ? 722 GLY A C 1 ATOM 5762 O O . GLY A 1 722 ? -26.800 -14.897 14.728 1.00 22.05 ? 722 GLY A O 1 ATOM 5763 N N . ASP A 1 723 ? -28.881 -14.044 14.480 1.00 20.78 ? 723 ASP A N 1 ATOM 5764 C CA . ASP A 1 723 ? -28.449 -12.646 14.426 1.00 20.28 ? 723 ASP A CA 1 ATOM 5765 C C . ASP A 1 723 ? -28.536 -11.920 15.774 1.00 19.29 ? 723 ASP A C 1 ATOM 5766 O O . ASP A 1 723 ? -28.373 -10.708 15.831 1.00 19.32 ? 723 ASP A O 1 ATOM 5767 C CB . ASP A 1 723 ? -29.193 -11.854 13.323 1.00 20.86 ? 723 ASP A CB 1 ATOM 5768 C CG . ASP A 1 723 ? -30.724 -11.769 13.559 1.00 23.55 ? 723 ASP A CG 1 ATOM 5769 O OD1 . ASP A 1 723 ? -31.284 -12.575 14.341 1.00 22.40 ? 723 ASP A OD1 1 ATOM 5770 O OD2 . ASP A 1 723 ? -31.356 -10.871 12.963 1.00 26.57 ? 723 ASP A OD2 1 ATOM 5771 N N . LYS A 1 724 ? -28.783 -12.640 16.869 1.00 18.77 ? 724 LYS A N 1 ATOM 5772 C CA . LYS A 1 724 ? -29.006 -11.953 18.144 1.00 17.74 ? 724 LYS A CA 1 ATOM 5773 C C . LYS A 1 724 ? -28.185 -12.485 19.323 1.00 17.24 ? 724 LYS A C 1 ATOM 5774 O O . LYS A 1 724 ? -27.837 -13.662 19.375 1.00 16.07 ? 724 LYS A O 1 ATOM 5775 C CB . LYS A 1 724 ? -30.504 -11.981 18.538 1.00 19.33 ? 724 LYS A CB 1 ATOM 5776 C CG . LYS A 1 724 ? -31.442 -11.361 17.519 1.00 18.83 ? 724 LYS A CG 1 ATOM 5777 C CD . LYS A 1 724 ? -31.393 -9.846 17.528 1.00 20.46 ? 724 LYS A CD 1 ATOM 5778 C CE . LYS A 1 724 ? -32.426 -9.292 16.528 1.00 24.93 ? 724 LYS A CE 1 ATOM 5779 N NZ . LYS A 1 724 ? -32.025 -7.952 15.971 1.00 28.24 ? 724 LYS A NZ 1 ATOM 5780 N N . ILE A 1 725 ? -27.898 -11.572 20.246 1.00 16.40 ? 725 ILE A N 1 ATOM 5781 C CA . ILE A 1 725 ? -27.434 -11.883 21.571 1.00 16.94 ? 725 ILE A CA 1 ATOM 5782 C C . ILE A 1 725 ? -28.379 -11.147 22.505 1.00 16.65 ? 725 ILE A C 1 ATOM 5783 O O . ILE A 1 725 ? -28.926 -10.110 22.138 1.00 17.61 ? 725 ILE A O 1 ATOM 5784 C CB . ILE A 1 725 ? -25.914 -11.492 21.786 1.00 16.44 ? 725 ILE A CB 1 ATOM 5785 C CG1 . ILE A 1 725 ? -25.485 -11.701 23.229 1.00 16.05 ? 725 ILE A CG1 1 ATOM 5786 C CG2 . ILE A 1 725 ? -25.618 -10.070 21.392 1.00 15.99 ? 725 ILE A CG2 1 ATOM 5787 C CD1 . ILE A 1 725 ? -23.962 -11.739 23.415 1.00 17.36 ? 725 ILE A CD1 1 ATOM 5788 N N . GLY A 1 726 ? -28.604 -11.699 23.690 1.00 16.38 ? 726 GLY A N 1 ATOM 5789 C CA . GLY A 1 726 ? -29.456 -11.037 24.682 1.00 16.26 ? 726 GLY A CA 1 ATOM 5790 C C . GLY A 1 726 ? -28.756 -9.845 25.296 1.00 15.73 ? 726 GLY A C 1 ATOM 5791 O O . GLY A 1 726 ? -27.656 -9.977 25.821 1.00 16.58 ? 726 GLY A O 1 ATOM 5792 N N . LEU A 1 727 ? -29.381 -8.676 25.214 1.00 15.96 ? 727 LEU A N 1 ATOM 5793 C CA . LEU A 1 727 ? -28.905 -7.490 25.892 1.00 16.38 ? 727 LEU A CA 1 ATOM 5794 C C . LEU A 1 727 ? -30.086 -6.856 26.602 1.00 16.51 ? 727 LEU A C 1 ATOM 5795 O O . LEU A 1 727 ? -31.029 -6.418 25.920 1.00 16.58 ? 727 LEU A O 1 ATOM 5796 C CB . LEU A 1 727 ? -28.304 -6.497 24.889 1.00 15.48 ? 727 LEU A CB 1 ATOM 5797 C CG . LEU A 1 727 ? -27.040 -6.931 24.138 1.00 17.68 ? 727 LEU A CG 1 ATOM 5798 C CD1 . LEU A 1 727 ? -26.733 -5.862 23.111 1.00 16.10 ? 727 LEU A CD1 1 ATOM 5799 C CD2 . LEU A 1 727 ? -25.873 -7.104 25.130 1.00 15.13 ? 727 LEU A CD2 1 ATOM 5800 N N . HIS A 1 728 ? -30.049 -6.790 27.944 1.00 16.09 ? 728 HIS A N 1 ATOM 5801 C CA . HIS A 1 728 ? -31.113 -6.074 28.704 1.00 15.23 ? 728 HIS A CA 1 ATOM 5802 C C . HIS A 1 728 ? -30.591 -5.011 29.650 1.00 15.32 ? 728 HIS A C 1 ATOM 5803 O O . HIS A 1 728 ? -29.555 -5.183 30.281 1.00 16.35 ? 728 HIS A O 1 ATOM 5804 C CB . HIS A 1 728 ? -32.035 -7.060 29.462 1.00 15.55 ? 728 HIS A CB 1 ATOM 5805 C CG . HIS A 1 728 ? -32.715 -8.029 28.557 1.00 15.65 ? 728 HIS A CG 1 ATOM 5806 N ND1 . HIS A 1 728 ? -32.082 -9.142 28.053 1.00 17.10 ? 728 HIS A ND1 1 ATOM 5807 C CD2 . HIS A 1 728 ? -33.959 -8.016 28.009 1.00 18.89 ? 728 HIS A CD2 1 ATOM 5808 C CE1 . HIS A 1 728 ? -32.905 -9.785 27.247 1.00 19.23 ? 728 HIS A CE1 1 ATOM 5809 N NE2 . HIS A 1 728 ? -34.050 -9.120 27.199 1.00 20.05 ? 728 HIS A NE2 1 ATOM 5810 N N . LEU A 1 729 ? -31.335 -3.915 29.741 1.00 14.67 ? 729 LEU A N 1 ATOM 5811 C CA . LEU A 1 729 ? -31.046 -2.787 30.608 1.00 14.81 ? 729 LEU A CA 1 ATOM 5812 C C . LEU A 1 729 ? -31.838 -2.892 31.887 1.00 15.36 ? 729 LEU A C 1 ATOM 5813 O O . LEU A 1 729 ? -33.089 -3.100 31.856 1.00 15.89 ? 729 LEU A O 1 ATOM 5814 C CB . LEU A 1 729 ? -31.406 -1.466 29.907 1.00 13.83 ? 729 LEU A CB 1 ATOM 5815 C CG . LEU A 1 729 ? -30.657 -1.227 28.596 1.00 15.55 ? 729 LEU A CG 1 ATOM 5816 C CD1 . LEU A 1 729 ? -31.101 0.065 27.954 1.00 17.72 ? 729 LEU A CD1 1 ATOM 5817 C CD2 . LEU A 1 729 ? -29.154 -1.187 28.873 1.00 11.49 ? 729 LEU A CD2 1 ATOM 5818 N N . ARG A 1 730 ? -31.125 -2.713 32.994 1.00 14.48 ? 730 ARG A N 1 ATOM 5819 C CA . ARG A 1 730 ? -31.675 -2.756 34.356 1.00 15.00 ? 730 ARG A CA 1 ATOM 5820 C C . ARG A 1 730 ? -32.484 -1.503 34.720 1.00 15.13 ? 730 ARG A C 1 ATOM 5821 O O . ARG A 1 730 ? -31.973 -0.391 34.646 1.00 15.08 ? 730 ARG A O 1 ATOM 5822 C CB . ARG A 1 730 ? -30.529 -3.010 35.363 1.00 14.67 ? 730 ARG A CB 1 ATOM 5823 C CG . ARG A 1 730 ? -30.969 -3.317 36.787 1.00 14.50 ? 730 ARG A CG 1 ATOM 5824 C CD . ARG A 1 730 ? -29.827 -3.734 37.629 1.00 14.14 ? 730 ARG A CD 1 ATOM 5825 N NE . ARG A 1 730 ? -30.143 -3.769 39.060 1.00 16.73 ? 730 ARG A NE 1 ATOM 5826 C CZ . ARG A 1 730 ? -29.212 -3.905 40.001 1.00 19.20 ? 730 ARG A CZ 1 ATOM 5827 N NH1 . ARG A 1 730 ? -27.928 -3.999 39.641 1.00 17.02 ? 730 ARG A NH1 1 ATOM 5828 N NH2 . ARG A 1 730 ? -29.552 -3.934 41.293 1.00 17.74 ? 730 ARG A NH2 1 ATOM 5829 N N . GLY A 1 731 ? -33.760 -1.671 35.083 1.00 15.05 ? 731 GLY A N 1 ATOM 5830 C CA . GLY A 1 731 ? -34.570 -0.547 35.539 1.00 15.01 ? 731 GLY A CA 1 ATOM 5831 C C . GLY A 1 731 ? -33.948 0.073 36.776 1.00 16.34 ? 731 GLY A C 1 ATOM 5832 O O . GLY A 1 731 ? -33.442 -0.643 37.636 1.00 16.73 ? 731 GLY A O 1 ATOM 5833 N N . GLY A 1 732 ? -33.963 1.401 36.883 1.00 15.44 ? 732 GLY A N 1 ATOM 5834 C CA . GLY A 1 732 ? -33.223 2.021 37.978 1.00 16.58 ? 732 GLY A CA 1 ATOM 5835 C C . GLY A 1 732 ? -31.893 2.621 37.558 1.00 16.09 ? 732 GLY A C 1 ATOM 5836 O O . GLY A 1 732 ? -31.223 3.233 38.356 1.00 16.20 ? 732 GLY A O 1 ATOM 5837 N N . TYR A 1 733 ? -31.547 2.511 36.279 1.00 16.40 ? 733 TYR A N 1 ATOM 5838 C CA . TYR A 1 733 ? -30.220 2.950 35.830 1.00 16.53 ? 733 TYR A CA 1 ATOM 5839 C C . TYR A 1 733 ? -30.295 3.835 34.586 1.00 15.97 ? 733 TYR A C 1 ATOM 5840 O O . TYR A 1 733 ? -31.145 3.642 33.734 1.00 15.91 ? 733 TYR A O 1 ATOM 5841 C CB . TYR A 1 733 ? -29.299 1.729 35.634 1.00 17.28 ? 733 TYR A CB 1 ATOM 5842 C CG . TYR A 1 733 ? -28.973 1.053 36.966 1.00 18.37 ? 733 TYR A CG 1 ATOM 5843 C CD1 . TYR A 1 733 ? -27.806 1.385 37.656 1.00 16.14 ? 733 TYR A CD1 1 ATOM 5844 C CD2 . TYR A 1 733 ? -29.845 0.128 37.543 1.00 17.37 ? 733 TYR A CD2 1 ATOM 5845 C CE1 . TYR A 1 733 ? -27.506 0.808 38.856 1.00 19.58 ? 733 TYR A CE1 1 ATOM 5846 C CE2 . TYR A 1 733 ? -29.551 -0.465 38.785 1.00 18.48 ? 733 TYR A CE2 1 ATOM 5847 C CZ . TYR A 1 733 ? -28.355 -0.122 39.416 1.00 19.67 ? 733 TYR A CZ 1 ATOM 5848 O OH . TYR A 1 733 ? -28.004 -0.647 40.652 1.00 22.88 ? 733 TYR A OH 1 ATOM 5849 N N . ILE A 1 734 ? -29.417 4.832 34.535 1.00 15.95 ? 734 ILE A N 1 ATOM 5850 C CA . ILE A 1 734 ? -29.306 5.763 33.403 1.00 15.41 ? 734 ILE A CA 1 ATOM 5851 C C . ILE A 1 734 ? -27.961 5.539 32.721 1.00 16.26 ? 734 ILE A C 1 ATOM 5852 O O . ILE A 1 734 ? -26.914 5.573 33.383 1.00 16.61 ? 734 ILE A O 1 ATOM 5853 C CB . ILE A 1 734 ? -29.470 7.236 33.851 1.00 15.40 ? 734 ILE A CB 1 ATOM 5854 C CG1 . ILE A 1 734 ? -30.845 7.414 34.529 1.00 15.17 ? 734 ILE A CG1 1 ATOM 5855 C CG2 . ILE A 1 734 ? -29.299 8.231 32.653 1.00 14.99 ? 734 ILE A CG2 1 ATOM 5856 C CD1 . ILE A 1 734 ? -31.095 8.763 35.153 1.00 13.76 ? 734 ILE A CD1 1 ATOM 5857 N N . PHE A 1 735 ? -28.031 5.276 31.414 1.00 16.62 ? 735 PHE A N 1 ATOM 5858 C CA . PHE A 1 735 ? -26.894 4.881 30.567 1.00 16.79 ? 735 PHE A CA 1 ATOM 5859 C C . PHE A 1 735 ? -26.569 6.005 29.600 1.00 16.61 ? 735 PHE A C 1 ATOM 5860 O O . PHE A 1 735 ? -27.419 6.374 28.759 1.00 17.30 ? 735 PHE A O 1 ATOM 5861 C CB . PHE A 1 735 ? -27.228 3.602 29.776 1.00 16.44 ? 735 PHE A CB 1 ATOM 5862 C CG . PHE A 1 735 ? -27.679 2.471 30.641 1.00 14.29 ? 735 PHE A CG 1 ATOM 5863 C CD1 . PHE A 1 735 ? -26.761 1.545 31.114 1.00 15.01 ? 735 PHE A CD1 1 ATOM 5864 C CD2 . PHE A 1 735 ? -29.021 2.347 31.002 1.00 13.77 ? 735 PHE A CD2 1 ATOM 5865 C CE1 . PHE A 1 735 ? -27.166 0.491 31.952 1.00 17.59 ? 735 PHE A CE1 1 ATOM 5866 C CE2 . PHE A 1 735 ? -29.442 1.319 31.846 1.00 12.02 ? 735 PHE A CE2 1 ATOM 5867 C CZ . PHE A 1 735 ? -28.500 0.372 32.302 1.00 15.77 ? 735 PHE A CZ 1 ATOM 5868 N N . PRO A 1 736 ? -25.370 6.580 29.741 1.00 16.26 ? 736 PRO A N 1 ATOM 5869 C CA . PRO A 1 736 ? -24.860 7.546 28.759 1.00 16.14 ? 736 PRO A CA 1 ATOM 5870 C C . PRO A 1 736 ? -24.406 6.856 27.497 1.00 15.96 ? 736 PRO A C 1 ATOM 5871 O O . PRO A 1 736 ? -23.717 5.819 27.563 1.00 15.67 ? 736 PRO A O 1 ATOM 5872 C CB . PRO A 1 736 ? -23.655 8.175 29.464 1.00 15.85 ? 736 PRO A CB 1 ATOM 5873 C CG . PRO A 1 736 ? -23.198 7.150 30.425 1.00 15.56 ? 736 PRO A CG 1 ATOM 5874 C CD . PRO A 1 736 ? -24.398 6.329 30.830 1.00 15.93 ? 736 PRO A CD 1 ATOM 5875 N N . THR A 1 737 ? -24.813 7.415 26.356 1.00 16.01 ? 737 THR A N 1 ATOM 5876 C CA . THR A 1 737 ? -24.437 6.909 25.034 1.00 16.27 ? 737 THR A CA 1 ATOM 5877 C C . THR A 1 737 ? -23.866 7.987 24.126 1.00 15.10 ? 737 THR A C 1 ATOM 5878 O O . THR A 1 737 ? -23.887 9.167 24.440 1.00 15.60 ? 737 THR A O 1 ATOM 5879 C CB . THR A 1 737 ? -25.621 6.192 24.297 1.00 17.45 ? 737 THR A CB 1 ATOM 5880 O OG1 . THR A 1 737 ? -26.608 7.154 23.899 1.00 20.87 ? 737 THR A OG1 1 ATOM 5881 C CG2 . THR A 1 737 ? -26.269 5.137 25.164 1.00 18.57 ? 737 THR A CG2 1 ATOM 5882 N N . GLN A 1 738 ? -23.338 7.567 22.992 1.00 14.57 ? 738 GLN A N 1 ATOM 5883 C CA . GLN A 1 738 ? -22.757 8.480 22.030 1.00 14.39 ? 738 GLN A CA 1 ATOM 5884 C C . GLN A 1 738 ? -22.878 7.832 20.684 1.00 14.10 ? 738 GLN A C 1 ATOM 5885 O O . GLN A 1 738 ? -22.554 6.664 20.526 1.00 13.20 ? 738 GLN A O 1 ATOM 5886 C CB . GLN A 1 738 ? -21.285 8.768 22.372 1.00 14.52 ? 738 GLN A CB 1 ATOM 5887 C CG . GLN A 1 738 ? -20.684 9.860 21.481 1.00 14.65 ? 738 GLN A CG 1 ATOM 5888 C CD . GLN A 1 738 ? -19.469 10.475 22.098 1.00 11.85 ? 738 GLN A CD 1 ATOM 5889 O OE1 . GLN A 1 738 ? -18.649 9.765 22.653 1.00 15.66 ? 738 GLN A OE1 1 ATOM 5890 N NE2 . GLN A 1 738 ? -19.314 11.790 21.968 1.00 9.63 ? 738 GLN A NE2 1 ATOM 5891 N N . GLN A 1 739 ? -23.368 8.581 19.706 1.00 15.76 ? 739 GLN A N 1 ATOM 5892 C CA . GLN A 1 739 ? -23.630 8.019 18.409 1.00 16.28 ? 739 GLN A CA 1 ATOM 5893 C C . GLN A 1 739 ? -22.317 7.386 17.946 1.00 17.00 ? 739 GLN A C 1 ATOM 5894 O O . GLN A 1 739 ? -21.258 8.002 18.066 1.00 18.25 ? 739 GLN A O 1 ATOM 5895 C CB . GLN A 1 739 ? -24.135 9.088 17.444 1.00 15.95 ? 739 GLN A CB 1 ATOM 5896 C CG . GLN A 1 739 ? -24.221 8.596 16.019 1.00 18.35 ? 739 GLN A CG 1 ATOM 5897 C CD . GLN A 1 739 ? -24.581 9.682 15.025 1.00 21.41 ? 739 GLN A CD 1 ATOM 5898 O OE1 . GLN A 1 739 ? -24.682 9.421 13.825 1.00 23.86 ? 739 GLN A OE1 1 ATOM 5899 N NE2 . GLN A 1 739 ? -24.775 10.894 15.510 1.00 23.20 ? 739 GLN A NE2 1 ATOM 5900 N N . PRO A 1 740 ? -22.376 6.132 17.476 1.00 17.73 ? 740 PRO A N 1 ATOM 5901 C CA . PRO A 1 740 ? -21.119 5.470 17.139 1.00 18.27 ? 740 PRO A CA 1 ATOM 5902 C C . PRO A 1 740 ? -20.545 5.840 15.767 1.00 19.54 ? 740 PRO A C 1 ATOM 5903 O O . PRO A 1 740 ? -21.252 6.302 14.881 1.00 19.05 ? 740 PRO A O 1 ATOM 5904 C CB . PRO A 1 740 ? -21.496 4.004 17.149 1.00 17.55 ? 740 PRO A CB 1 ATOM 5905 C CG . PRO A 1 740 ? -22.942 4.005 16.676 1.00 17.81 ? 740 PRO A CG 1 ATOM 5906 C CD . PRO A 1 740 ? -23.547 5.247 17.301 1.00 16.56 ? 740 PRO A CD 1 ATOM 5907 N N . ASN A 1 741 ? -19.246 5.628 15.619 1.00 19.99 ? 741 ASN A N 1 ATOM 5908 C CA . ASN A 1 741 ? -18.598 5.736 14.335 1.00 21.22 ? 741 ASN A CA 1 ATOM 5909 C C . ASN A 1 741 ? -17.617 4.561 14.306 1.00 21.44 ? 741 ASN A C 1 ATOM 5910 O O . ASN A 1 741 ? -17.477 3.831 15.299 1.00 21.74 ? 741 ASN A O 1 ATOM 5911 C CB . ASN A 1 741 ? -17.872 7.097 14.229 1.00 21.30 ? 741 ASN A CB 1 ATOM 5912 C CG . ASN A 1 741 ? -17.740 7.624 12.772 1.00 24.15 ? 741 ASN A CG 1 ATOM 5913 O OD1 . ASN A 1 741 ? -17.895 6.894 11.794 1.00 23.75 ? 741 ASN A OD1 1 ATOM 5914 N ND2 . ASN A 1 741 ? -17.429 8.910 12.652 1.00 30.84 ? 741 ASN A ND2 1 ATOM 5915 N N . THR A 1 742 ? -16.934 4.377 13.188 1.00 20.98 ? 742 THR A N 1 ATOM 5916 C CA . THR A 1 742 ? -16.022 3.233 13.015 1.00 20.15 ? 742 THR A CA 1 ATOM 5917 C C . THR A 1 742 ? -14.729 3.336 13.839 1.00 19.44 ? 742 THR A C 1 ATOM 5918 O O . THR A 1 742 ? -13.999 2.353 13.968 1.00 20.28 ? 742 THR A O 1 ATOM 5919 C CB . THR A 1 742 ? -15.679 3.034 11.522 1.00 20.25 ? 742 THR A CB 1 ATOM 5920 O OG1 . THR A 1 742 ? -15.083 4.232 11.011 1.00 20.42 ? 742 THR A OG1 1 ATOM 5921 C CG2 . THR A 1 742 ? -16.922 2.751 10.743 1.00 19.42 ? 742 THR A CG2 1 ATOM 5922 N N . THR A 1 743 ? -14.449 4.515 14.382 1.00 18.42 ? 743 THR A N 1 ATOM 5923 C CA . THR A 1 743 ? -13.345 4.719 15.307 1.00 19.51 ? 743 THR A CA 1 ATOM 5924 C C . THR A 1 743 ? -13.814 5.560 16.496 1.00 19.40 ? 743 THR A C 1 ATOM 5925 O O . THR A 1 743 ? -14.729 6.354 16.350 1.00 19.14 ? 743 THR A O 1 ATOM 5926 C CB . THR A 1 743 ? -12.150 5.433 14.624 1.00 19.52 ? 743 THR A CB 1 ATOM 5927 O OG1 . THR A 1 743 ? -12.542 6.761 14.287 1.00 21.06 ? 743 THR A OG1 1 ATOM 5928 C CG2 . THR A 1 743 ? -11.749 4.715 13.328 1.00 18.63 ? 743 THR A CG2 1 ATOM 5929 N N . THR A 1 744 ? -13.188 5.391 17.659 1.00 20.19 ? 744 THR A N 1 ATOM 5930 C CA . THR A 1 744 ? -13.461 6.258 18.819 1.00 21.19 ? 744 THR A CA 1 ATOM 5931 C C . THR A 1 744 ? -12.909 7.664 18.645 1.00 21.88 ? 744 THR A C 1 ATOM 5932 O O . THR A 1 744 ? -13.368 8.593 19.314 1.00 21.94 ? 744 THR A O 1 ATOM 5933 C CB . THR A 1 744 ? -12.916 5.697 20.138 1.00 21.27 ? 744 THR A CB 1 ATOM 5934 O OG1 . THR A 1 744 ? -11.476 5.620 20.062 1.00 21.71 ? 744 THR A OG1 1 ATOM 5935 C CG2 . THR A 1 744 ? -13.522 4.315 20.446 1.00 20.65 ? 744 THR A CG2 1 ATOM 5936 N N . LEU A 1 745 ? -11.918 7.831 17.763 1.00 21.98 ? 745 LEU A N 1 ATOM 5937 C CA . LEU A 1 745 ? -11.423 9.171 17.442 1.00 22.00 ? 745 LEU A CA 1 ATOM 5938 C C . LEU A 1 745 ? -12.585 10.012 16.920 1.00 22.03 ? 745 LEU A C 1 ATOM 5939 O O . LEU A 1 745 ? -12.834 11.119 17.399 1.00 23.05 ? 745 LEU A O 1 ATOM 5940 C CB . LEU A 1 745 ? -10.293 9.135 16.390 1.00 21.79 ? 745 LEU A CB 1 ATOM 5941 C CG . LEU A 1 745 ? -9.795 10.527 15.994 1.00 23.32 ? 745 LEU A CG 1 ATOM 5942 C CD1 . LEU A 1 745 ? -8.820 11.008 17.020 1.00 25.38 ? 745 LEU A CD1 1 ATOM 5943 C CD2 . LEU A 1 745 ? -9.171 10.534 14.627 1.00 24.93 ? 745 LEU A CD2 1 ATOM 5944 N N . ALA A 1 746 ? -13.276 9.474 15.932 1.00 22.02 ? 746 ALA A N 1 ATOM 5945 C CA . ALA A 1 746 ? -14.482 10.102 15.379 1.00 22.33 ? 746 ALA A CA 1 ATOM 5946 C C . ALA A 1 746 ? -15.641 10.064 16.360 1.00 21.94 ? 746 ALA A C 1 ATOM 5947 O O . ALA A 1 746 ? -16.257 11.078 16.601 1.00 21.99 ? 746 ALA A O 1 ATOM 5948 C CB . ALA A 1 746 ? -14.883 9.426 14.097 1.00 21.31 ? 746 ALA A CB 1 ATOM 5949 N N . SER A 1 747 ? -15.928 8.889 16.917 1.00 21.96 ? 747 SER A N 1 ATOM 5950 C CA . SER A 1 747 ? -17.112 8.689 17.778 1.00 21.34 ? 747 SER A CA 1 ATOM 5951 C C . SER A 1 747 ? -17.187 9.696 18.920 1.00 20.51 ? 747 SER A C 1 ATOM 5952 O O . SER A 1 747 ? -18.253 10.204 19.226 1.00 19.76 ? 747 SER A O 1 ATOM 5953 C CB . SER A 1 747 ? -17.208 7.234 18.288 1.00 21.13 ? 747 SER A CB 1 ATOM 5954 O OG . SER A 1 747 ? -16.428 7.012 19.459 1.00 24.50 ? 747 SER A OG 1 ATOM 5955 N N . ARG A 1 748 ? -16.048 10.038 19.519 1.00 20.14 ? 748 ARG A N 1 ATOM 5956 C CA . ARG A 1 748 ? -16.052 10.960 20.656 1.00 19.65 ? 748 ARG A CA 1 ATOM 5957 C C . ARG A 1 748 ? -16.536 12.391 20.365 1.00 19.50 ? 748 ARG A C 1 ATOM 5958 O O . ARG A 1 748 ? -16.820 13.149 21.306 1.00 19.17 ? 748 ARG A O 1 ATOM 5959 C CB . ARG A 1 748 ? -14.680 11.011 21.287 1.00 19.68 ? 748 ARG A CB 1 ATOM 5960 C CG . ARG A 1 748 ? -14.275 9.714 21.976 1.00 19.62 ? 748 ARG A CG 1 ATOM 5961 C CD . ARG A 1 748 ? -12.813 9.799 22.349 1.00 18.89 ? 748 ARG A CD 1 ATOM 5962 N NE . ARG A 1 748 ? -12.555 11.051 23.055 1.00 19.11 ? 748 ARG A NE 1 ATOM 5963 C CZ . ARG A 1 748 ? -12.712 11.219 24.366 1.00 19.63 ? 748 ARG A CZ 1 ATOM 5964 N NH1 . ARG A 1 748 ? -13.088 10.205 25.131 1.00 22.39 ? 748 ARG A NH1 1 ATOM 5965 N NH2 . ARG A 1 748 ? -12.467 12.395 24.923 1.00 19.94 ? 748 ARG A NH2 1 ATOM 5966 N N . LYS A 1 749 ? -16.629 12.746 19.081 1.00 18.84 ? 749 LYS A N 1 ATOM 5967 C CA . LYS A 1 749 ? -17.154 14.041 18.622 1.00 18.75 ? 749 LYS A CA 1 ATOM 5968 C C . LYS A 1 749 ? -18.667 14.032 18.337 1.00 18.09 ? 749 LYS A C 1 ATOM 5969 O O . LYS A 1 749 ? -19.250 15.042 17.929 1.00 17.86 ? 749 LYS A O 1 ATOM 5970 C CB . LYS A 1 749 ? -16.421 14.462 17.348 1.00 19.56 ? 749 LYS A CB 1 ATOM 5971 C CG . LYS A 1 749 ? -14.870 14.540 17.528 1.00 19.45 ? 749 LYS A CG 1 ATOM 5972 C CD . LYS A 1 749 ? -14.164 14.814 16.207 1.00 20.17 ? 749 LYS A CD 1 ATOM 5973 C CE . LYS A 1 749 ? -12.646 14.977 16.427 1.00 22.82 ? 749 LYS A CE 1 ATOM 5974 N NZ . LYS A 1 749 ? -11.820 14.865 15.160 1.00 28.91 ? 749 LYS A NZ 1 ATOM 5975 N N . ASN A 1 750 ? -19.300 12.897 18.542 1.00 17.80 ? 750 ASN A N 1 ATOM 5976 C CA . ASN A 1 750 ? -20.709 12.744 18.170 1.00 17.57 ? 750 ASN A CA 1 ATOM 5977 C C . ASN A 1 750 ? -21.698 13.178 19.278 1.00 17.55 ? 750 ASN A C 1 ATOM 5978 O O . ASN A 1 750 ? -21.323 13.260 20.440 1.00 17.18 ? 750 ASN A O 1 ATOM 5979 C CB . ASN A 1 750 ? -20.960 11.312 17.686 1.00 16.71 ? 750 ASN A CB 1 ATOM 5980 C CG . ASN A 1 750 ? -20.578 11.100 16.216 1.00 16.66 ? 750 ASN A CG 1 ATOM 5981 O OD1 . ASN A 1 750 ? -20.422 12.046 15.471 1.00 20.04 ? 750 ASN A OD1 1 ATOM 5982 N ND2 . ASN A 1 750 ? -20.436 9.853 15.805 1.00 13.05 ? 750 ASN A ND2 1 ATOM 5983 N N . PRO A 1 751 ? -22.974 13.466 18.916 1.00 18.24 ? 751 PRO A N 1 ATOM 5984 C CA . PRO A 1 751 ? -24.006 13.699 19.922 1.00 18.45 ? 751 PRO A CA 1 ATOM 5985 C C . PRO A 1 751 ? -24.117 12.564 20.937 1.00 16.92 ? 751 PRO A C 1 ATOM 5986 O O . PRO A 1 751 ? -24.003 11.404 20.599 1.00 17.68 ? 751 PRO A O 1 ATOM 5987 C CB . PRO A 1 751 ? -25.296 13.757 19.076 1.00 18.62 ? 751 PRO A CB 1 ATOM 5988 C CG . PRO A 1 751 ? -24.818 14.363 17.819 1.00 20.09 ? 751 PRO A CG 1 ATOM 5989 C CD . PRO A 1 751 ? -23.529 13.629 17.564 1.00 19.43 ? 751 PRO A CD 1 ATOM 5990 N N . LEU A 1 752 ? -24.352 12.922 22.175 1.00 17.00 ? 752 LEU A N 1 ATOM 5991 C CA . LEU A 1 752 ? -24.590 11.958 23.209 1.00 17.91 ? 752 LEU A CA 1 ATOM 5992 C C . LEU A 1 752 ? -26.081 11.754 23.405 1.00 18.19 ? 752 LEU A C 1 ATOM 5993 O O . LEU A 1 752 ? -26.911 12.485 22.864 1.00 18.30 ? 752 LEU A O 1 ATOM 5994 C CB . LEU A 1 752 ? -23.982 12.449 24.518 1.00 18.79 ? 752 LEU A CB 1 ATOM 5995 C CG . LEU A 1 752 ? -22.582 13.006 24.402 1.00 19.46 ? 752 LEU A CG 1 ATOM 5996 C CD1 . LEU A 1 752 ? -22.445 14.106 25.467 1.00 23.10 ? 752 LEU A CD1 1 ATOM 5997 C CD2 . LEU A 1 752 ? -21.604 11.896 24.623 1.00 22.94 ? 752 LEU A CD2 1 ATOM 5998 N N . GLY A 1 753 ? -26.399 10.748 24.200 1.00 18.20 ? 753 GLY A N 1 ATOM 5999 C CA . GLY A 1 753 ? -27.771 10.374 24.487 1.00 17.99 ? 753 GLY A CA 1 ATOM 6000 C C . GLY A 1 753 ? -27.774 9.834 25.899 1.00 18.41 ? 753 GLY A C 1 ATOM 6001 O O . GLY A 1 753 ? -26.704 9.546 26.492 1.00 17.64 ? 753 GLY A O 1 ATOM 6002 N N . LEU A 1 754 ? -28.969 9.752 26.457 1.00 17.83 ? 754 LEU A N 1 ATOM 6003 C CA . LEU A 1 754 ? -29.195 9.100 27.718 1.00 18.81 ? 754 LEU A CA 1 ATOM 6004 C C . LEU A 1 754 ? -30.248 8.015 27.516 1.00 19.21 ? 754 LEU A C 1 ATOM 6005 O O . LEU A 1 754 ? -31.271 8.258 26.866 1.00 20.39 ? 754 LEU A O 1 ATOM 6006 C CB . LEU A 1 754 ? -29.661 10.100 28.785 1.00 17.87 ? 754 LEU A CB 1 ATOM 6007 C CG . LEU A 1 754 ? -28.712 11.185 29.277 1.00 18.65 ? 754 LEU A CG 1 ATOM 6008 C CD1 . LEU A 1 754 ? -29.393 12.080 30.291 1.00 17.97 ? 754 LEU A CD1 1 ATOM 6009 C CD2 . LEU A 1 754 ? -27.471 10.549 29.884 1.00 14.39 ? 754 LEU A CD2 1 ATOM 6010 N N . ILE A 1 755 ? -30.001 6.834 28.068 1.00 19.11 ? 755 ILE A N 1 ATOM 6011 C CA . ILE A 1 755 ? -31.058 5.821 28.234 1.00 19.69 ? 755 ILE A CA 1 ATOM 6012 C C . ILE A 1 755 ? -31.414 5.743 29.716 1.00 19.68 ? 755 ILE A C 1 ATOM 6013 O O . ILE A 1 755 ? -30.573 5.403 30.535 1.00 20.23 ? 755 ILE A O 1 ATOM 6014 C CB . ILE A 1 755 ? -30.715 4.414 27.684 1.00 18.79 ? 755 ILE A CB 1 ATOM 6015 C CG1 . ILE A 1 755 ? -30.225 4.494 26.230 1.00 19.75 ? 755 ILE A CG1 1 ATOM 6016 C CG2 . ILE A 1 755 ? -31.962 3.503 27.767 1.00 18.05 ? 755 ILE A CG2 1 ATOM 6017 C CD1 . ILE A 1 755 ? -29.449 3.246 25.776 1.00 20.27 ? 755 ILE A CD1 1 ATOM 6018 N N . ILE A 1 756 ? -32.653 6.135 30.031 1.00 20.02 ? 756 ILE A N 1 ATOM 6019 C CA . ILE A 1 756 ? -33.225 6.101 31.372 1.00 19.03 ? 756 ILE A CA 1 ATOM 6020 C C . ILE A 1 756 ? -34.143 4.852 31.412 1.00 19.99 ? 756 ILE A C 1 ATOM 6021 O O . ILE A 1 756 ? -35.209 4.840 30.803 1.00 19.48 ? 756 ILE A O 1 ATOM 6022 C CB . ILE A 1 756 ? -34.059 7.399 31.644 1.00 19.38 ? 756 ILE A CB 1 ATOM 6023 C CG1 . ILE A 1 756 ? -33.164 8.658 31.592 1.00 17.74 ? 756 ILE A CG1 1 ATOM 6024 C CG2 . ILE A 1 756 ? -34.811 7.312 32.943 1.00 16.95 ? 756 ILE A CG2 1 ATOM 6025 C CD1 . ILE A 1 756 ? -33.917 9.961 31.421 1.00 18.20 ? 756 ILE A CD1 1 ATOM 6026 N N . ALA A 1 757 ? -33.709 3.795 32.098 1.00 19.94 ? 757 ALA A N 1 ATOM 6027 C CA . ALA A 1 757 ? -34.546 2.636 32.337 1.00 18.55 ? 757 ALA A CA 1 ATOM 6028 C C . ALA A 1 757 ? -35.140 2.805 33.717 1.00 19.14 ? 757 ALA A C 1 ATOM 6029 O O . ALA A 1 757 ? -34.465 2.638 34.714 1.00 18.12 ? 757 ALA A O 1 ATOM 6030 C CB . ALA A 1 757 ? -33.731 1.376 32.276 1.00 19.58 ? 757 ALA A CB 1 ATOM 6031 N N . LEU A 1 758 ? -36.428 3.106 33.776 1.00 18.66 ? 758 LEU A N 1 ATOM 6032 C CA . LEU A 1 758 ? -37.063 3.357 35.050 1.00 19.28 ? 758 LEU A CA 1 ATOM 6033 C C . LEU A 1 758 ? -37.246 2.073 35.863 1.00 19.37 ? 758 LEU A C 1 ATOM 6034 O O . LEU A 1 758 ? -37.517 1.013 35.303 1.00 19.86 ? 758 LEU A O 1 ATOM 6035 C CB . LEU A 1 758 ? -38.409 4.089 34.840 1.00 18.28 ? 758 LEU A CB 1 ATOM 6036 C CG . LEU A 1 758 ? -38.405 5.461 34.173 1.00 18.45 ? 758 LEU A CG 1 ATOM 6037 C CD1 . LEU A 1 758 ? -39.845 5.984 33.985 1.00 18.59 ? 758 LEU A CD1 1 ATOM 6038 C CD2 . LEU A 1 758 ? -37.581 6.479 34.949 1.00 19.47 ? 758 LEU A CD2 1 ATOM 6039 N N . ASP A 1 759 ? -37.081 2.170 37.182 1.00 21.10 ? 759 ASP A N 1 ATOM 6040 C CA . ASP A 1 759 ? -37.418 1.058 38.068 1.00 23.21 ? 759 ASP A CA 1 ATOM 6041 C C . ASP A 1 759 ? -38.921 1.064 38.369 1.00 24.54 ? 759 ASP A C 1 ATOM 6042 O O . ASP A 1 759 ? -39.662 1.872 37.793 1.00 25.23 ? 759 ASP A O 1 ATOM 6043 C CB . ASP A 1 759 ? -36.544 1.010 39.344 1.00 22.90 ? 759 ASP A CB 1 ATOM 6044 C CG . ASP A 1 759 ? -36.785 2.171 40.304 1.00 24.33 ? 759 ASP A CG 1 ATOM 6045 O OD1 . ASP A 1 759 ? -37.813 2.873 40.216 1.00 24.85 ? 759 ASP A OD1 1 ATOM 6046 O OD2 . ASP A 1 759 ? -35.907 2.402 41.165 1.00 27.72 ? 759 ASP A OD2 1 ATOM 6047 N N . GLU A 1 760 ? -39.347 0.164 39.257 1.00 26.28 ? 760 GLU A N 1 ATOM 6048 C CA . GLU A 1 760 ? -40.741 -0.035 39.623 1.00 28.33 ? 760 GLU A CA 1 ATOM 6049 C C . GLU A 1 760 ? -41.309 1.245 40.241 1.00 28.28 ? 760 GLU A C 1 ATOM 6050 O O . GLU A 1 760 ? -42.501 1.529 40.131 1.00 29.03 ? 760 GLU A O 1 ATOM 6051 C CB . GLU A 1 760 ? -40.846 -1.208 40.617 1.00 29.33 ? 760 GLU A CB 1 ATOM 6052 C CG . GLU A 1 760 ? -39.885 -2.395 40.321 1.00 33.17 ? 760 GLU A CG 1 ATOM 6053 C CD . GLU A 1 760 ? -38.600 -2.442 41.174 1.00 38.13 ? 760 GLU A CD 1 ATOM 6054 O OE1 . GLU A 1 760 ? -38.615 -3.150 42.214 1.00 39.86 ? 760 GLU A OE1 1 ATOM 6055 O OE2 . GLU A 1 760 ? -37.574 -1.813 40.810 1.00 37.73 ? 760 GLU A OE2 1 ATOM 6056 N N . ASN A 1 761 ? -40.444 2.034 40.874 1.00 27.51 ? 761 ASN A N 1 ATOM 6057 C CA . ASN A 1 761 ? -40.867 3.325 41.413 1.00 26.98 ? 761 ASN A CA 1 ATOM 6058 C C . ASN A 1 761 ? -40.733 4.514 40.461 1.00 25.41 ? 761 ASN A C 1 ATOM 6059 O O . ASN A 1 761 ? -40.857 5.650 40.883 1.00 26.14 ? 761 ASN A O 1 ATOM 6060 C CB . ASN A 1 761 ? -40.160 3.588 42.740 1.00 27.29 ? 761 ASN A CB 1 ATOM 6061 C CG . ASN A 1 761 ? -40.366 2.447 43.731 1.00 30.66 ? 761 ASN A CG 1 ATOM 6062 O OD1 . ASN A 1 761 ? -41.473 1.902 43.843 1.00 33.00 ? 761 ASN A OD1 1 ATOM 6063 N ND2 . ASN A 1 761 ? -39.296 2.057 44.429 1.00 31.39 ? 761 ASN A ND2 1 ATOM 6064 N N . LYS A 1 762 ? -40.508 4.241 39.179 1.00 23.74 ? 762 LYS A N 1 ATOM 6065 C CA . LYS A 1 762 ? -40.343 5.277 38.128 1.00 22.48 ? 762 LYS A CA 1 ATOM 6066 C C . LYS A 1 762 ? -39.172 6.232 38.411 1.00 21.57 ? 762 LYS A C 1 ATOM 6067 O O . LYS A 1 762 ? -39.240 7.438 38.139 1.00 20.26 ? 762 LYS A O 1 ATOM 6068 C CB . LYS A 1 762 ? -41.675 6.014 37.806 1.00 23.44 ? 762 LYS A CB 1 ATOM 6069 C CG . LYS A 1 762 ? -42.828 5.037 37.451 1.00 24.01 ? 762 LYS A CG 1 ATOM 6070 C CD . LYS A 1 762 ? -42.318 3.942 36.502 1.00 26.00 ? 762 LYS A CD 1 ATOM 6071 C CE . LYS A 1 762 ? -43.194 2.715 36.429 1.00 28.57 ? 762 LYS A CE 1 ATOM 6072 N NZ . LYS A 1 762 ? -42.476 1.658 35.654 1.00 29.20 ? 762 LYS A NZ 1 ATOM 6073 N N . GLU A 1 763 ? -38.096 5.661 38.956 1.00 20.44 ? 763 GLU A N 1 ATOM 6074 C CA . GLU A 1 763 ? -36.881 6.406 39.316 1.00 20.75 ? 763 GLU A CA 1 ATOM 6075 C C . GLU A 1 763 ? -35.696 5.704 38.659 1.00 18.57 ? 763 GLU A C 1 ATOM 6076 O O . GLU A 1 763 ? -35.803 4.556 38.238 1.00 17.56 ? 763 GLU A O 1 ATOM 6077 C CB . GLU A 1 763 ? -36.660 6.480 40.860 1.00 20.85 ? 763 GLU A CB 1 ATOM 6078 C CG . GLU A 1 763 ? -37.920 6.817 41.684 1.00 25.26 ? 763 GLU A CG 1 ATOM 6079 C CD . GLU A 1 763 ? -37.650 7.368 43.083 1.00 25.97 ? 763 GLU A CD 1 ATOM 6080 O OE1 . GLU A 1 763 ? -36.612 7.040 43.724 1.00 31.71 ? 763 GLU A OE1 1 ATOM 6081 O OE2 . GLU A 1 763 ? -38.509 8.153 43.538 1.00 31.71 ? 763 GLU A OE2 1 ATOM 6082 N N . ALA A 1 764 ? -34.577 6.413 38.549 1.00 17.10 ? 764 ALA A N 1 ATOM 6083 C CA . ALA A 1 764 ? -33.392 5.880 37.903 1.00 16.47 ? 764 ALA A CA 1 ATOM 6084 C C . ALA A 1 764 ? -32.253 6.805 38.217 1.00 15.87 ? 764 ALA A C 1 ATOM 6085 O O . ALA A 1 764 ? -32.473 7.960 38.530 1.00 16.00 ? 764 ALA A O 1 ATOM 6086 C CB . ALA A 1 764 ? -33.588 5.751 36.382 1.00 15.57 ? 764 ALA A CB 1 ATOM 6087 N N . LYS A 1 765 ? -31.032 6.285 38.163 1.00 16.41 ? 765 LYS A N 1 ATOM 6088 C CA . LYS A 1 765 ? -29.842 7.049 38.508 1.00 17.20 ? 765 LYS A CA 1 ATOM 6089 C C . LYS A 1 765 ? -28.722 6.586 37.619 1.00 16.48 ? 765 LYS A C 1 ATOM 6090 O O . LYS A 1 765 ? -28.714 5.449 37.169 1.00 15.95 ? 765 LYS A O 1 ATOM 6091 C CB . LYS A 1 765 ? -29.461 6.836 39.982 1.00 17.51 ? 765 LYS A CB 1 ATOM 6092 C CG . LYS A 1 765 ? -30.219 7.742 40.951 1.00 21.32 ? 765 LYS A CG 1 ATOM 6093 C CD . LYS A 1 765 ? -30.025 7.306 42.390 1.00 22.56 ? 765 LYS A CD 1 ATOM 6094 C CE . LYS A 1 765 ? -30.328 8.446 43.385 1.00 31.73 ? 765 LYS A CE 1 ATOM 6095 N NZ . LYS A 1 765 ? -29.504 9.690 43.117 1.00 31.94 ? 765 LYS A NZ 1 ATOM 6096 N N . GLY A 1 766 ? -27.777 7.478 37.342 1.00 16.59 ? 766 GLY A N 1 ATOM 6097 C CA . GLY A 1 766 ? -26.636 7.107 36.536 1.00 17.14 ? 766 GLY A CA 1 ATOM 6098 C C . GLY A 1 766 ? -25.552 8.140 36.707 1.00 17.14 ? 766 GLY A C 1 ATOM 6099 O O . GLY A 1 766 ? -25.727 9.136 37.422 1.00 17.49 ? 766 GLY A O 1 ATOM 6100 N N . GLU A 1 767 ? -24.435 7.909 36.053 1.00 17.06 ? 767 GLU A N 1 ATOM 6101 C CA . GLU A 1 767 ? -23.381 8.912 36.028 1.00 17.85 ? 767 GLU A CA 1 ATOM 6102 C C . GLU A 1 767 ? -22.659 8.896 34.698 1.00 16.92 ? 767 GLU A C 1 ATOM 6103 O O . GLU A 1 767 ? -22.866 7.994 33.897 1.00 17.04 ? 767 GLU A O 1 ATOM 6104 C CB . GLU A 1 767 ? -22.417 8.708 37.180 1.00 17.92 ? 767 GLU A CB 1 ATOM 6105 C CG . GLU A 1 767 ? -21.744 7.347 37.158 1.00 21.54 ? 767 GLU A CG 1 ATOM 6106 C CD . GLU A 1 767 ? -20.864 7.121 38.363 1.00 27.23 ? 767 GLU A CD 1 ATOM 6107 O OE1 . GLU A 1 767 ? -20.866 7.997 39.249 1.00 27.95 ? 767 GLU A OE1 1 ATOM 6108 O OE2 . GLU A 1 767 ? -20.164 6.079 38.417 1.00 27.94 ? 767 GLU A OE2 1 ATOM 6109 N N . LEU A 1 768 ? -21.840 9.918 34.455 1.00 16.60 ? 768 LEU A N 1 ATOM 6110 C CA . LEU A 1 768 ? -20.977 9.946 33.295 1.00 16.47 ? 768 LEU A CA 1 ATOM 6111 C C . LEU A 1 768 ? -19.661 10.610 33.662 1.00 16.23 ? 768 LEU A C 1 ATOM 6112 O O . LEU A 1 768 ? -19.665 11.733 34.153 1.00 15.93 ? 768 LEU A O 1 ATOM 6113 C CB . LEU A 1 768 ? -21.611 10.737 32.129 1.00 17.10 ? 768 LEU A CB 1 ATOM 6114 C CG . LEU A 1 768 ? -20.638 10.958 30.947 1.00 16.22 ? 768 LEU A CG 1 ATOM 6115 C CD1 . LEU A 1 768 ? -20.333 9.662 30.171 1.00 11.33 ? 768 LEU A CD1 1 ATOM 6116 C CD2 . LEU A 1 768 ? -21.151 12.040 30.021 1.00 17.66 ? 768 LEU A CD2 1 ATOM 6117 N N . PHE A 1 769 ? -18.554 9.911 33.390 1.00 15.24 ? 769 PHE A N 1 ATOM 6118 C CA . PHE A 1 769 ? -17.206 10.451 33.492 1.00 14.54 ? 769 PHE A CA 1 ATOM 6119 C C . PHE A 1 769 ? -16.742 10.863 32.088 1.00 14.51 ? 769 PHE A C 1 ATOM 6120 O O . PHE A 1 769 ? -16.971 10.120 31.146 1.00 15.19 ? 769 PHE A O 1 ATOM 6121 C CB . PHE A 1 769 ? -16.254 9.354 34.011 1.00 14.41 ? 769 PHE A CB 1 ATOM 6122 C CG . PHE A 1 769 ? -14.799 9.749 33.987 1.00 14.56 ? 769 PHE A CG 1 ATOM 6123 C CD1 . PHE A 1 769 ? -14.290 10.589 34.955 1.00 13.97 ? 769 PHE A CD1 1 ATOM 6124 C CD2 . PHE A 1 769 ? -13.932 9.240 33.019 1.00 14.07 ? 769 PHE A CD2 1 ATOM 6125 C CE1 . PHE A 1 769 ? -12.920 10.933 34.958 1.00 13.91 ? 769 PHE A CE1 1 ATOM 6126 C CE2 . PHE A 1 769 ? -12.580 9.599 33.003 1.00 13.70 ? 769 PHE A CE2 1 ATOM 6127 C CZ . PHE A 1 769 ? -12.086 10.435 33.960 1.00 16.73 ? 769 PHE A CZ 1 ATOM 6128 N N . TRP A 1 770 ? -16.110 12.034 31.948 1.00 14.14 ? 770 TRP A N 1 ATOM 6129 C CA . TRP A 1 770 ? -15.580 12.454 30.653 1.00 14.30 ? 770 TRP A CA 1 ATOM 6130 C C . TRP A 1 770 ? -14.266 13.198 30.821 1.00 14.40 ? 770 TRP A C 1 ATOM 6131 O O . TRP A 1 770 ? -14.184 14.176 31.553 1.00 15.35 ? 770 TRP A O 1 ATOM 6132 C CB . TRP A 1 770 ? -16.556 13.346 29.889 1.00 12.58 ? 770 TRP A CB 1 ATOM 6133 C CG . TRP A 1 770 ? -16.322 13.401 28.393 1.00 12.21 ? 770 TRP A CG 1 ATOM 6134 C CD1 . TRP A 1 770 ? -15.863 14.487 27.665 1.00 8.42 ? 770 TRP A CD1 1 ATOM 6135 C CD2 . TRP A 1 770 ? -16.500 12.335 27.442 1.00 10.65 ? 770 TRP A CD2 1 ATOM 6136 N NE1 . TRP A 1 770 ? -15.774 14.153 26.345 1.00 7.96 ? 770 TRP A NE1 1 ATOM 6137 C CE2 . TRP A 1 770 ? -16.153 12.847 26.175 1.00 7.57 ? 770 TRP A CE2 1 ATOM 6138 C CE3 . TRP A 1 770 ? -16.960 11.006 27.534 1.00 13.11 ? 770 TRP A CE3 1 ATOM 6139 C CZ2 . TRP A 1 770 ? -16.256 12.096 25.016 1.00 7.33 ? 770 TRP A CZ2 1 ATOM 6140 C CZ3 . TRP A 1 770 ? -17.023 10.251 26.382 1.00 12.35 ? 770 TRP A CZ3 1 ATOM 6141 C CH2 . TRP A 1 770 ? -16.688 10.801 25.135 1.00 10.47 ? 770 TRP A CH2 1 ATOM 6142 N N . ASP A 1 771 ? -13.254 12.758 30.109 1.00 14.67 ? 771 ASP A N 1 ATOM 6143 C CA . ASP A 1 771 ? -11.996 13.514 30.102 1.00 16.04 ? 771 ASP A CA 1 ATOM 6144 C C . ASP A 1 771 ? -11.452 13.482 28.675 1.00 16.18 ? 771 ASP A C 1 ATOM 6145 O O . ASP A 1 771 ? -12.167 13.098 27.762 1.00 16.96 ? 771 ASP A O 1 ATOM 6146 C CB . ASP A 1 771 ? -11.037 12.959 31.162 1.00 15.32 ? 771 ASP A CB 1 ATOM 6147 C CG . ASP A 1 771 ? -10.549 11.566 30.854 1.00 15.18 ? 771 ASP A CG 1 ATOM 6148 O OD1 . ASP A 1 771 ? -11.032 10.954 29.883 1.00 19.28 ? 771 ASP A OD1 1 ATOM 6149 O OD2 . ASP A 1 771 ? -9.655 11.068 31.585 1.00 14.75 ? 771 ASP A OD2 1 ATOM 6150 N N . ASP A 1 772 ? -10.189 13.835 28.470 1.00 16.09 ? 772 ASP A N 1 ATOM 6151 C CA . ASP A 1 772 ? -9.673 13.841 27.120 1.00 14.77 ? 772 ASP A CA 1 ATOM 6152 C C . ASP A 1 772 ? -9.450 12.441 26.525 1.00 13.86 ? 772 ASP A C 1 ATOM 6153 O O . ASP A 1 772 ? -9.258 12.292 25.323 1.00 12.67 ? 772 ASP A O 1 ATOM 6154 C CB . ASP A 1 772 ? -8.470 14.793 26.988 1.00 15.40 ? 772 ASP A CB 1 ATOM 6155 C CG . ASP A 1 772 ? -7.188 14.213 27.583 1.00 17.56 ? 772 ASP A CG 1 ATOM 6156 O OD1 . ASP A 1 772 ? -7.187 13.043 28.052 1.00 15.90 ? 772 ASP A OD1 1 ATOM 6157 O OD2 . ASP A 1 772 ? -6.179 14.952 27.562 1.00 19.76 ? 772 ASP A OD2 1 ATOM 6158 N N . GLY A 1 773 ? -9.537 11.405 27.350 1.00 13.82 ? 773 GLY A N 1 ATOM 6159 C CA . GLY A 1 773 ? -9.515 10.039 26.834 1.00 14.14 ? 773 GLY A CA 1 ATOM 6160 C C . GLY A 1 773 ? -8.134 9.469 26.532 1.00 15.30 ? 773 GLY A C 1 ATOM 6161 O O . GLY A 1 773 ? -8.020 8.357 26.015 1.00 15.01 ? 773 GLY A O 1 ATOM 6162 N N . GLU A 1 774 ? -7.073 10.204 26.849 1.00 16.31 ? 774 GLU A N 1 ATOM 6163 C CA . GLU A 1 774 ? -5.736 9.682 26.539 1.00 18.94 ? 774 GLU A CA 1 ATOM 6164 C C . GLU A 1 774 ? -4.627 10.227 27.442 1.00 20.17 ? 774 GLU A C 1 ATOM 6165 O O . GLU A 1 774 ? -3.554 9.592 27.561 1.00 21.56 ? 774 GLU A O 1 ATOM 6166 C CB . GLU A 1 774 ? -5.410 9.947 25.058 1.00 19.24 ? 774 GLU A CB 1 ATOM 6167 C CG . GLU A 1 774 ? -5.214 11.421 24.767 1.00 21.18 ? 774 GLU A CG 1 ATOM 6168 C CD . GLU A 1 774 ? -5.050 11.736 23.299 1.00 26.46 ? 774 GLU A CD 1 ATOM 6169 O OE1 . GLU A 1 774 ? -4.810 10.816 22.489 1.00 28.20 ? 774 GLU A OE1 1 ATOM 6170 O OE2 . GLU A 1 774 ? -5.170 12.934 22.960 1.00 32.86 ? 774 GLU A OE2 1 ATOM 6171 N N . THR A 1 775 ? -4.864 11.367 28.092 1.00 21.68 ? 775 THR A N 1 ATOM 6172 C CA . THR A 1 775 ? -3.842 11.963 28.974 1.00 23.26 ? 775 THR A CA 1 ATOM 6173 C C . THR A 1 775 ? -3.678 11.185 30.295 1.00 24.03 ? 775 THR A C 1 ATOM 6174 O O . THR A 1 775 ? -4.672 10.796 30.931 1.00 22.80 ? 775 THR A O 1 ATOM 6175 C CB . THR A 1 775 ? -4.082 13.487 29.213 1.00 24.09 ? 775 THR A CB 1 ATOM 6176 O OG1 . THR A 1 775 ? -4.222 14.150 27.951 1.00 23.40 ? 775 THR A OG1 1 ATOM 6177 C CG2 . THR A 1 775 ? -2.924 14.119 29.938 1.00 23.34 ? 775 THR A CG2 1 ATOM 6178 N N . LYS A 1 776 ? -2.427 10.922 30.685 1.00 24.50 ? 776 LYS A N 1 ATOM 6179 C CA . LYS A 1 776 ? -2.168 10.229 31.949 1.00 26.72 ? 776 LYS A CA 1 ATOM 6180 C C . LYS A 1 776 ? -2.393 11.247 33.075 1.00 27.32 ? 776 LYS A C 1 ATOM 6181 O O . LYS A 1 776 ? -2.137 12.423 32.895 1.00 28.50 ? 776 LYS A O 1 ATOM 6182 C CB . LYS A 1 776 ? -0.736 9.681 31.985 1.00 26.93 ? 776 LYS A CB 1 ATOM 6183 C CG . LYS A 1 776 ? -0.620 8.201 32.351 1.00 28.59 ? 776 LYS A CG 1 ATOM 6184 C CD . LYS A 1 776 ? 0.843 7.719 32.339 1.00 27.96 ? 776 LYS A CD 1 ATOM 6185 C CE . LYS A 1 776 ? 0.902 6.221 32.000 1.00 30.00 ? 776 LYS A CE 1 ATOM 6186 N NZ . LYS A 1 776 ? 2.271 5.666 31.757 1.00 31.87 ? 776 LYS A NZ 1 ATOM 6187 N N . ASP A 1 777 ? -2.901 10.818 34.221 1.00 28.05 ? 777 ASP A N 1 ATOM 6188 C CA . ASP A 1 777 ? -3.012 11.732 35.358 1.00 28.72 ? 777 ASP A CA 1 ATOM 6189 C C . ASP A 1 777 ? -4.276 12.606 35.337 1.00 27.62 ? 777 ASP A C 1 ATOM 6190 O O . ASP A 1 777 ? -4.369 13.527 36.127 1.00 27.40 ? 777 ASP A O 1 ATOM 6191 C CB . ASP A 1 777 ? -1.803 12.698 35.417 1.00 29.90 ? 777 ASP A CB 1 ATOM 6192 C CG . ASP A 1 777 ? -0.506 12.041 35.904 1.00 33.76 ? 777 ASP A CG 1 ATOM 6193 O OD1 . ASP A 1 777 ? -0.549 11.059 36.690 1.00 36.36 ? 777 ASP A OD1 1 ATOM 6194 O OD2 . ASP A 1 777 ? 0.579 12.554 35.511 1.00 38.06 ? 777 ASP A OD2 1 ATOM 6195 N N . THR A 1 778 ? -5.230 12.364 34.440 1.00 26.95 ? 778 THR A N 1 ATOM 6196 C CA . THR A 1 778 ? -6.399 13.254 34.397 1.00 26.31 ? 778 THR A CA 1 ATOM 6197 C C . THR A 1 778 ? -7.211 13.145 35.675 1.00 26.02 ? 778 THR A C 1 ATOM 6198 O O . THR A 1 778 ? -7.830 14.121 36.076 1.00 26.46 ? 778 THR A O 1 ATOM 6199 C CB . THR A 1 778 ? -7.345 13.018 33.209 1.00 26.41 ? 778 THR A CB 1 ATOM 6200 O OG1 . THR A 1 778 ? -7.882 11.692 33.270 1.00 25.07 ? 778 THR A OG1 1 ATOM 6201 C CG2 . THR A 1 778 ? -6.631 13.231 31.899 1.00 24.78 ? 778 THR A CG2 1 ATOM 6202 N N . VAL A 1 779 ? -7.193 11.973 36.312 1.00 25.08 ? 779 VAL A N 1 ATOM 6203 C CA . VAL A 1 779 ? -7.964 11.745 37.536 1.00 25.53 ? 779 VAL A CA 1 ATOM 6204 C C . VAL A 1 779 ? -7.233 12.342 38.747 1.00 26.34 ? 779 VAL A C 1 ATOM 6205 O O . VAL A 1 779 ? -7.796 13.170 39.468 1.00 25.53 ? 779 VAL A O 1 ATOM 6206 C CB . VAL A 1 779 ? -8.307 10.258 37.726 1.00 25.19 ? 779 VAL A CB 1 ATOM 6207 C CG1 . VAL A 1 779 ? -8.935 10.014 39.075 1.00 25.02 ? 779 VAL A CG1 1 ATOM 6208 C CG2 . VAL A 1 779 ? -9.239 9.794 36.618 1.00 24.72 ? 779 VAL A CG2 1 ATOM 6209 N N . ALA A 1 780 ? -5.964 11.965 38.918 1.00 26.72 ? 780 ALA A N 1 ATOM 6210 C CA . ALA A 1 780 ? -5.119 12.496 39.982 1.00 28.14 ? 780 ALA A CA 1 ATOM 6211 C C . ALA A 1 780 ? -5.076 14.011 39.968 1.00 28.79 ? 780 ALA A C 1 ATOM 6212 O O . ALA A 1 780 ? -5.060 14.644 41.023 1.00 29.46 ? 780 ALA A O 1 ATOM 6213 C CB . ALA A 1 780 ? -3.688 11.922 39.889 1.00 27.80 ? 780 ALA A CB 1 ATOM 6214 N N . ASN A 1 781 ? -5.058 14.590 38.771 1.00 30.19 ? 781 ASN A N 1 ATOM 6215 C CA . ASN A 1 781 ? -4.957 16.034 38.603 1.00 30.64 ? 781 ASN A CA 1 ATOM 6216 C C . ASN A 1 781 ? -6.300 16.720 38.416 1.00 30.01 ? 781 ASN A C 1 ATOM 6217 O O . ASN A 1 781 ? -6.364 17.932 38.221 1.00 30.31 ? 781 ASN A O 1 ATOM 6218 C CB . ASN A 1 781 ? -4.025 16.370 37.441 1.00 31.41 ? 781 ASN A CB 1 ATOM 6219 C CG . ASN A 1 781 ? -2.579 16.128 37.780 1.00 34.33 ? 781 ASN A CG 1 ATOM 6220 O OD1 . ASN A 1 781 ? -1.826 15.597 36.973 1.00 37.57 ? 781 ASN A OD1 1 ATOM 6221 N ND2 . ASN A 1 781 ? -2.185 16.499 38.988 1.00 35.73 ? 781 ASN A ND2 1 ATOM 6222 N N . LYS A 1 782 ? -7.370 15.938 38.484 1.00 29.31 ? 782 LYS A N 1 ATOM 6223 C CA . LYS A 1 782 ? -8.730 16.470 38.439 1.00 27.91 ? 782 LYS A CA 1 ATOM 6224 C C . LYS A 1 782 ? -8.942 17.352 37.220 1.00 26.50 ? 782 LYS A C 1 ATOM 6225 O O . LYS A 1 782 ? -9.318 18.515 37.339 1.00 26.44 ? 782 LYS A O 1 ATOM 6226 C CB . LYS A 1 782 ? -9.048 17.246 39.728 1.00 28.98 ? 782 LYS A CB 1 ATOM 6227 C CG . LYS A 1 782 ? -8.779 16.478 40.999 1.00 30.34 ? 782 LYS A CG 1 ATOM 6228 C CD . LYS A 1 782 ? -10.021 15.802 41.490 1.00 36.40 ? 782 LYS A CD 1 ATOM 6229 C CE . LYS A 1 782 ? -9.773 15.133 42.841 1.00 38.63 ? 782 LYS A CE 1 ATOM 6230 N NZ . LYS A 1 782 ? -10.538 13.853 42.963 1.00 40.86 ? 782 LYS A NZ 1 ATOM 6231 N N . VAL A 1 783 ? -8.673 16.791 36.045 1.00 24.74 ? 783 VAL A N 1 ATOM 6232 C CA . VAL A 1 783 ? -8.994 17.432 34.789 1.00 22.81 ? 783 VAL A CA 1 ATOM 6233 C C . VAL A 1 783 ? -9.991 16.481 34.141 1.00 22.05 ? 783 VAL A C 1 ATOM 6234 O O . VAL A 1 783 ? -9.647 15.667 33.265 1.00 21.57 ? 783 VAL A O 1 ATOM 6235 C CB . VAL A 1 783 ? -7.756 17.695 33.891 1.00 22.81 ? 783 VAL A CB 1 ATOM 6236 C CG1 . VAL A 1 783 ? -8.173 18.497 32.667 1.00 22.78 ? 783 VAL A CG1 1 ATOM 6237 C CG2 . VAL A 1 783 ? -6.662 18.480 34.656 1.00 24.18 ? 783 VAL A CG2 1 ATOM 6238 N N . TYR A 1 784 ? -11.228 16.577 34.612 1.00 20.76 ? 784 TYR A N 1 ATOM 6239 C CA . TYR A 1 784 ? -12.293 15.754 34.096 1.00 20.63 ? 784 TYR A CA 1 ATOM 6240 C C . TYR A 1 784 ? -13.669 16.296 34.425 1.00 20.02 ? 784 TYR A C 1 ATOM 6241 O O . TYR A 1 784 ? -13.845 17.127 35.307 1.00 19.95 ? 784 TYR A O 1 ATOM 6242 C CB . TYR A 1 784 ? -12.168 14.301 34.576 1.00 20.09 ? 784 TYR A CB 1 ATOM 6243 C CG . TYR A 1 784 ? -12.283 14.026 36.083 1.00 20.64 ? 784 TYR A CG 1 ATOM 6244 C CD1 . TYR A 1 784 ? -13.518 13.743 36.670 1.00 19.75 ? 784 TYR A CD1 1 ATOM 6245 C CD2 . TYR A 1 784 ? -11.143 13.936 36.887 1.00 20.79 ? 784 TYR A CD2 1 ATOM 6246 C CE1 . TYR A 1 784 ? -13.628 13.443 38.014 1.00 20.24 ? 784 TYR A CE1 1 ATOM 6247 C CE2 . TYR A 1 784 ? -11.239 13.650 38.243 1.00 21.93 ? 784 TYR A CE2 1 ATOM 6248 C CZ . TYR A 1 784 ? -12.489 13.401 38.800 1.00 19.93 ? 784 TYR A CZ 1 ATOM 6249 O OH . TYR A 1 784 ? -12.590 13.088 40.130 1.00 19.73 ? 784 TYR A OH 1 ATOM 6250 N N . LEU A 1 785 ? -14.651 15.790 33.709 1.00 19.73 ? 785 LEU A N 1 ATOM 6251 C CA . LEU A 1 785 ? -16.025 16.073 34.046 1.00 19.65 ? 785 LEU A CA 1 ATOM 6252 C C . LEU A 1 785 ? -16.657 14.858 34.740 1.00 19.92 ? 785 LEU A C 1 ATOM 6253 O O . LEU A 1 785 ? -16.555 13.745 34.252 1.00 20.42 ? 785 LEU A O 1 ATOM 6254 C CB . LEU A 1 785 ? -16.770 16.395 32.758 1.00 19.86 ? 785 LEU A CB 1 ATOM 6255 C CG . LEU A 1 785 ? -18.293 16.373 32.887 1.00 20.77 ? 785 LEU A CG 1 ATOM 6256 C CD1 . LEU A 1 785 ? -18.727 17.591 33.672 1.00 16.53 ? 785 LEU A CD1 1 ATOM 6257 C CD2 . LEU A 1 785 ? -18.851 16.365 31.509 1.00 22.20 ? 785 LEU A CD2 1 ATOM 6258 N N . LEU A 1 786 ? -17.305 15.048 35.887 1.00 19.80 ? 786 LEU A N 1 ATOM 6259 C CA . LEU A 1 786 ? -18.155 13.974 36.400 1.00 19.47 ? 786 LEU A CA 1 ATOM 6260 C C . LEU A 1 786 ? -19.545 14.509 36.643 1.00 20.24 ? 786 LEU A C 1 ATOM 6261 O O . LEU A 1 786 ? -19.717 15.504 37.339 1.00 20.33 ? 786 LEU A O 1 ATOM 6262 C CB . LEU A 1 786 ? -17.578 13.290 37.653 1.00 18.96 ? 786 LEU A CB 1 ATOM 6263 C CG . LEU A 1 786 ? -18.278 12.023 38.196 1.00 19.15 ? 786 LEU A CG 1 ATOM 6264 C CD1 . LEU A 1 786 ? -18.160 10.808 37.261 1.00 17.04 ? 786 LEU A CD1 1 ATOM 6265 C CD2 . LEU A 1 786 ? -17.764 11.658 39.584 1.00 18.44 ? 786 LEU A CD2 1 ATOM 6266 N N . CYS A 1 787 ? -20.537 13.857 36.050 1.00 20.77 ? 787 CYS A N 1 ATOM 6267 C CA . CYS A 1 787 ? -21.914 14.270 36.230 1.00 22.29 ? 787 CYS A CA 1 ATOM 6268 C C . CYS A 1 787 ? -22.847 13.134 36.619 1.00 21.53 ? 787 CYS A C 1 ATOM 6269 O O . CYS A 1 787 ? -22.553 11.971 36.385 1.00 19.46 ? 787 CYS A O 1 ATOM 6270 C CB . CYS A 1 787 ? -22.462 15.027 35.016 1.00 22.89 ? 787 CYS A CB 1 ATOM 6271 S SG . CYS A 1 787 ? -22.375 14.250 33.448 1.00 29.05 ? 787 CYS A SG 1 ATOM 6272 N N . GLU A 1 788 ? -23.956 13.508 37.242 1.00 21.26 ? 788 GLU A N 1 ATOM 6273 C CA . GLU A 1 788 ? -24.934 12.551 37.743 1.00 22.16 ? 788 GLU A CA 1 ATOM 6274 C C . GLU A 1 788 ? -26.312 12.880 37.262 1.00 22.18 ? 788 GLU A C 1 ATOM 6275 O O . GLU A 1 788 ? -26.728 14.051 37.207 1.00 22.85 ? 788 GLU A O 1 ATOM 6276 C CB . GLU A 1 788 ? -24.930 12.416 39.277 1.00 22.30 ? 788 GLU A CB 1 ATOM 6277 C CG . GLU A 1 788 ? -24.048 13.355 40.029 1.00 27.29 ? 788 GLU A CG 1 ATOM 6278 C CD . GLU A 1 788 ? -22.604 12.876 40.114 1.00 32.72 ? 788 GLU A CD 1 ATOM 6279 O OE1 . GLU A 1 788 ? -21.751 13.755 40.332 1.00 35.36 ? 788 GLU A OE1 1 ATOM 6280 O OE2 . GLU A 1 788 ? -22.317 11.647 39.977 1.00 35.97 ? 788 GLU A OE2 1 ATOM 6281 N N . PHE A 1 789 ? -26.999 11.825 36.871 1.00 22.09 ? 789 PHE A N 1 ATOM 6282 C CA . PHE A 1 789 ? -28.329 11.898 36.346 1.00 22.48 ? 789 PHE A CA 1 ATOM 6283 C C . PHE A 1 789 ? -29.180 11.239 37.400 1.00 22.83 ? 789 PHE A C 1 ATOM 6284 O O . PHE A 1 789 ? -28.823 10.179 37.923 1.00 22.11 ? 789 PHE A O 1 ATOM 6285 C CB . PHE A 1 789 ? -28.406 11.141 35.007 1.00 22.61 ? 789 PHE A CB 1 ATOM 6286 C CG . PHE A 1 789 ? -27.234 11.420 34.077 1.00 21.15 ? 789 PHE A CG 1 ATOM 6287 C CD1 . PHE A 1 789 ? -27.138 12.641 33.404 1.00 20.52 ? 789 PHE A CD1 1 ATOM 6288 C CD2 . PHE A 1 789 ? -26.240 10.456 33.880 1.00 22.28 ? 789 PHE A CD2 1 ATOM 6289 C CE1 . PHE A 1 789 ? -26.061 12.925 32.557 1.00 22.54 ? 789 PHE A CE1 1 ATOM 6290 C CE2 . PHE A 1 789 ? -25.139 10.715 33.018 1.00 24.87 ? 789 PHE A CE2 1 ATOM 6291 C CZ . PHE A 1 789 ? -25.058 11.951 32.355 1.00 24.33 ? 789 PHE A CZ 1 ATOM 6292 N N . SER A 1 790 ? -30.261 11.907 37.770 1.00 24.36 ? 790 SER A N 1 ATOM 6293 C CA . SER A 1 790 ? -31.312 11.286 38.564 1.00 25.86 ? 790 SER A CA 1 ATOM 6294 C C . SER A 1 790 ? -32.709 11.578 38.016 1.00 26.48 ? 790 SER A C 1 ATOM 6295 O O . SER A 1 790 ? -32.990 12.683 37.582 1.00 26.76 ? 790 SER A O 1 ATOM 6296 C CB . SER A 1 790 ? -31.200 11.658 40.058 1.00 26.69 ? 790 SER A CB 1 ATOM 6297 O OG . SER A 1 790 ? -30.496 12.877 40.286 1.00 29.41 ? 790 SER A OG 1 ATOM 6298 N N . VAL A 1 791 ? -33.573 10.567 38.033 1.00 27.32 ? 791 VAL A N 1 ATOM 6299 C CA . VAL A 1 791 ? -34.977 10.711 37.647 1.00 28.90 ? 791 VAL A CA 1 ATOM 6300 C C . VAL A 1 791 ? -35.829 10.324 38.865 1.00 30.17 ? 791 VAL A C 1 ATOM 6301 O O . VAL A 1 791 ? -35.652 9.241 39.412 1.00 29.39 ? 791 VAL A O 1 ATOM 6302 C CB . VAL A 1 791 ? -35.347 9.814 36.416 1.00 28.29 ? 791 VAL A CB 1 ATOM 6303 C CG1 . VAL A 1 791 ? -36.860 9.838 36.148 1.00 29.29 ? 791 VAL A CG1 1 ATOM 6304 C CG2 . VAL A 1 791 ? -34.609 10.264 35.193 1.00 28.70 ? 791 VAL A CG2 1 ATOM 6305 N N . THR A 1 792 ? -36.694 11.235 39.319 1.00 32.41 ? 792 THR A N 1 ATOM 6306 C CA . THR A 1 792 ? -37.688 10.940 40.360 1.00 35.19 ? 792 THR A CA 1 ATOM 6307 C C . THR A 1 792 ? -38.985 11.564 39.908 1.00 36.43 ? 792 THR A C 1 ATOM 6308 O O . THR A 1 792 ? -39.049 12.796 39.769 1.00 37.35 ? 792 THR A O 1 ATOM 6309 C CB . THR A 1 792 ? -37.358 11.538 41.747 1.00 35.20 ? 792 THR A CB 1 ATOM 6310 O OG1 . THR A 1 792 ? -36.001 11.265 42.105 1.00 37.02 ? 792 THR A OG1 1 ATOM 6311 C CG2 . THR A 1 792 ? -38.253 10.908 42.798 1.00 36.92 ? 792 THR A CG2 1 ATOM 6312 N N . GLN A 1 793 ? -40.009 10.719 39.753 1.00 37.22 ? 793 GLN A N 1 ATOM 6313 C CA . GLN A 1 793 ? -41.192 10.973 38.901 1.00 38.36 ? 793 GLN A CA 1 ATOM 6314 C C . GLN A 1 793 ? -41.348 12.393 38.342 1.00 37.30 ? 793 GLN A C 1 ATOM 6315 O O . GLN A 1 793 ? -41.318 13.401 39.078 1.00 37.95 ? 793 GLN A O 1 ATOM 6316 C CB . GLN A 1 793 ? -42.518 10.403 39.492 1.00 38.14 ? 793 GLN A CB 1 ATOM 6317 C CG . GLN A 1 793 ? -43.278 11.291 40.502 1.00 40.63 ? 793 GLN A CG 1 ATOM 6318 C CD . GLN A 1 793 ? -44.820 11.237 40.335 1.00 40.97 ? 793 GLN A CD 1 ATOM 6319 O OE1 . GLN A 1 793 ? -45.539 12.145 40.781 1.00 46.27 ? 793 GLN A OE1 1 ATOM 6320 N NE2 . GLN A 1 793 ? -45.319 10.185 39.683 1.00 42.50 ? 793 GLN A NE2 1 ATOM 6321 N N . ASN A 1 794 ? -41.497 12.453 37.021 1.00 35.87 ? 794 ASN A N 1 ATOM 6322 C CA . ASN A 1 794 ? -41.719 13.713 36.321 1.00 34.80 ? 794 ASN A CA 1 ATOM 6323 C C . ASN A 1 794 ? -40.486 14.615 36.162 1.00 33.12 ? 794 ASN A C 1 ATOM 6324 O O . ASN A 1 794 ? -40.645 15.753 35.719 1.00 32.12 ? 794 ASN A O 1 ATOM 6325 C CB . ASN A 1 794 ? -42.854 14.530 36.982 1.00 35.50 ? 794 ASN A CB 1 ATOM 6326 C CG . ASN A 1 794 ? -44.101 13.695 37.285 1.00 37.96 ? 794 ASN A CG 1 ATOM 6327 O OD1 . ASN A 1 794 ? -44.809 13.957 38.265 1.00 41.68 ? 794 ASN A OD1 1 ATOM 6328 N ND2 . ASN A 1 794 ? -44.362 12.684 36.464 1.00 38.23 ? 794 ASN A ND2 1 ATOM 6329 N N . ARG A 1 795 ? -39.283 14.146 36.526 1.00 31.12 ? 795 ARG A N 1 ATOM 6330 C CA . ARG A 1 795 ? -38.121 15.053 36.575 1.00 30.05 ? 795 ARG A CA 1 ATOM 6331 C C . ARG A 1 795 ? -36.756 14.366 36.401 1.00 28.97 ? 795 ARG A C 1 ATOM 6332 O O . ARG A 1 795 ? -36.383 13.525 37.222 1.00 28.53 ? 795 ARG A O 1 ATOM 6333 C CB . ARG A 1 795 ? -38.154 15.831 37.893 1.00 30.56 ? 795 ARG A CB 1 ATOM 6334 C CG . ARG A 1 795 ? -37.149 16.947 38.078 1.00 32.08 ? 795 ARG A CG 1 ATOM 6335 C CD . ARG A 1 795 ? -37.320 17.509 39.486 1.00 37.80 ? 795 ARG A CD 1 ATOM 6336 N NE . ARG A 1 795 ? -36.339 18.525 39.866 1.00 42.96 ? 795 ARG A NE 1 ATOM 6337 C CZ . ARG A 1 795 ? -36.634 19.800 40.134 1.00 45.64 ? 795 ARG A CZ 1 ATOM 6338 N NH1 . ARG A 1 795 ? -37.895 20.237 40.055 1.00 48.08 ? 795 ARG A NH1 1 ATOM 6339 N NH2 . ARG A 1 795 ? -35.669 20.646 40.480 1.00 45.93 ? 795 ARG A NH2 1 ATOM 6340 N N . LEU A 1 796 ? -36.030 14.736 35.341 1.00 27.01 ? 796 LEU A N 1 ATOM 6341 C CA . LEU A 1 796 ? -34.612 14.367 35.175 1.00 25.73 ? 796 LEU A CA 1 ATOM 6342 C C . LEU A 1 796 ? -33.702 15.516 35.613 1.00 25.49 ? 796 LEU A C 1 ATOM 6343 O O . LEU A 1 796 ? -33.831 16.643 35.136 1.00 25.50 ? 796 LEU A O 1 ATOM 6344 C CB . LEU A 1 796 ? -34.279 13.953 33.725 1.00 24.47 ? 796 LEU A CB 1 ATOM 6345 C CG . LEU A 1 796 ? -32.781 13.958 33.352 1.00 23.92 ? 796 LEU A CG 1 ATOM 6346 C CD1 . LEU A 1 796 ? -32.025 12.785 33.957 1.00 19.99 ? 796 LEU A CD1 1 ATOM 6347 C CD2 . LEU A 1 796 ? -32.584 14.006 31.846 1.00 24.90 ? 796 LEU A CD2 1 ATOM 6348 N N . GLU A 1 797 ? -32.783 15.233 36.526 1.00 25.58 ? 797 GLU A N 1 ATOM 6349 C CA . GLU A 1 797 ? -31.805 16.223 36.953 1.00 26.46 ? 797 GLU A CA 1 ATOM 6350 C C . GLU A 1 797 ? -30.411 15.820 36.492 1.00 25.60 ? 797 GLU A C 1 ATOM 6351 O O . GLU A 1 797 ? -29.997 14.677 36.671 1.00 24.49 ? 797 GLU A O 1 ATOM 6352 C CB . GLU A 1 797 ? -31.811 16.395 38.478 1.00 26.33 ? 797 GLU A CB 1 ATOM 6353 C CG . GLU A 1 797 ? -33.166 16.827 39.068 1.00 28.49 ? 797 GLU A CG 1 ATOM 6354 C CD . GLU A 1 797 ? -33.062 17.272 40.524 1.00 31.15 ? 797 GLU A CD 1 ATOM 6355 O OE1 . GLU A 1 797 ? -32.488 16.509 41.353 1.00 38.15 ? 797 GLU A OE1 1 ATOM 6356 O OE2 . GLU A 1 797 ? -33.551 18.390 40.846 1.00 37.73 ? 797 GLU A OE2 1 ATOM 6357 N N . VAL A 1 798 ? -29.695 16.760 35.885 1.00 25.66 ? 798 VAL A N 1 ATOM 6358 C CA . VAL A 1 798 ? -28.290 16.539 35.525 1.00 25.36 ? 798 VAL A CA 1 ATOM 6359 C C . VAL A 1 798 ? -27.515 17.418 36.488 1.00 24.90 ? 798 VAL A C 1 ATOM 6360 O O . VAL A 1 798 ? -27.671 18.622 36.494 1.00 24.87 ? 798 VAL A O 1 ATOM 6361 C CB . VAL A 1 798 ? -27.994 16.847 34.019 1.00 25.82 ? 798 VAL A CB 1 ATOM 6362 C CG1 . VAL A 1 798 ? -26.499 16.690 33.691 1.00 25.16 ? 798 VAL A CG1 1 ATOM 6363 C CG2 . VAL A 1 798 ? -28.856 15.960 33.093 1.00 26.58 ? 798 VAL A CG2 1 ATOM 6364 N N . ASN A 1 799 ? -26.781 16.786 37.385 1.00 25.33 ? 799 ASN A N 1 ATOM 6365 C CA . ASN A 1 799 ? -25.951 17.471 38.359 1.00 26.96 ? 799 ASN A CA 1 ATOM 6366 C C . ASN A 1 799 ? -24.511 17.327 37.927 1.00 26.33 ? 799 ASN A C 1 ATOM 6367 O O . ASN A 1 799 ? -24.143 16.319 37.342 1.00 26.47 ? 799 ASN A O 1 ATOM 6368 C CB . ASN A 1 799 ? -26.109 16.824 39.738 1.00 27.60 ? 799 ASN A CB 1 ATOM 6369 C CG . ASN A 1 799 ? -25.960 17.820 40.877 1.00 32.40 ? 799 ASN A CG 1 ATOM 6370 O OD1 . ASN A 1 799 ? -25.529 18.964 40.674 1.00 39.65 ? 799 ASN A OD1 1 ATOM 6371 N ND2 . ASN A 1 799 ? -26.335 17.399 42.091 1.00 35.97 ? 799 ASN A ND2 1 ATOM 6372 N N . ILE A 1 800 ? -23.696 18.320 38.234 1.00 26.14 ? 800 ILE A N 1 ATOM 6373 C CA . ILE A 1 800 ? -22.298 18.290 37.870 1.00 25.95 ? 800 ILE A CA 1 ATOM 6374 C C . ILE A 1 800 ? -21.500 18.293 39.153 1.00 26.05 ? 800 ILE A C 1 ATOM 6375 O O . ILE A 1 800 ? -21.566 19.251 39.901 1.00 26.38 ? 800 ILE A O 1 ATOM 6376 C CB . ILE A 1 800 ? -21.903 19.526 37.021 1.00 26.01 ? 800 ILE A CB 1 ATOM 6377 C CG1 . ILE A 1 800 ? -22.905 19.789 35.878 1.00 25.09 ? 800 ILE A CG1 1 ATOM 6378 C CG2 . ILE A 1 800 ? -20.471 19.383 36.512 1.00 26.46 ? 800 ILE A CG2 1 ATOM 6379 C CD1 . ILE A 1 800 ? -23.072 18.674 34.867 1.00 25.25 ? 800 ILE A CD1 1 ATOM 6380 N N . SER A 1 801 ? -20.764 17.223 39.432 1.00 26.23 ? 801 SER A N 1 ATOM 6381 C CA . SER A 1 801 ? -19.950 17.212 40.644 1.00 26.90 ? 801 SER A CA 1 ATOM 6382 C C . SER A 1 801 ? -18.490 17.622 40.444 1.00 26.90 ? 801 SER A C 1 ATOM 6383 O O . SER A 1 801 ? -17.888 18.168 41.366 1.00 27.48 ? 801 SER A O 1 ATOM 6384 C CB . SER A 1 801 ? -20.063 15.888 41.406 1.00 27.09 ? 801 SER A CB 1 ATOM 6385 O OG . SER A 1 801 ? -19.433 14.828 40.716 1.00 27.28 ? 801 SER A OG 1 ATOM 6386 N N . GLN A 1 802 ? -17.933 17.388 39.258 1.00 26.56 ? 802 GLN A N 1 ATOM 6387 C CA . GLN A 1 802 ? -16.562 17.808 38.948 1.00 27.09 ? 802 GLN A CA 1 ATOM 6388 C C . GLN A 1 802 ? -16.622 18.379 37.551 1.00 27.06 ? 802 GLN A C 1 ATOM 6389 O O . GLN A 1 802 ? -17.168 17.762 36.639 1.00 27.43 ? 802 GLN A O 1 ATOM 6390 C CB . GLN A 1 802 ? -15.580 16.627 39.040 1.00 26.87 ? 802 GLN A CB 1 ATOM 6391 C CG . GLN A 1 802 ? -14.120 16.941 38.713 1.00 29.04 ? 802 GLN A CG 1 ATOM 6392 C CD . GLN A 1 802 ? -13.414 17.657 39.838 1.00 31.17 ? 802 GLN A CD 1 ATOM 6393 O OE1 . GLN A 1 802 ? -12.599 18.551 39.609 1.00 36.22 ? 802 GLN A OE1 1 ATOM 6394 N NE2 . GLN A 1 802 ? -13.727 17.282 41.061 1.00 32.15 ? 802 GLN A NE2 1 ATOM 6395 N N . SER A 1 803 ? -16.099 19.578 37.387 1.00 27.16 ? 803 SER A N 1 ATOM 6396 C CA . SER A 1 803 ? -16.269 20.291 36.142 1.00 28.21 ? 803 SER A CA 1 ATOM 6397 C C . SER A 1 803 ? -14.991 20.988 35.741 1.00 27.79 ? 803 SER A C 1 ATOM 6398 O O . SER A 1 803 ? -14.978 22.194 35.526 1.00 28.87 ? 803 SER A O 1 ATOM 6399 C CB . SER A 1 803 ? -17.397 21.311 36.270 1.00 27.99 ? 803 SER A CB 1 ATOM 6400 O OG . SER A 1 803 ? -17.751 21.754 34.988 1.00 31.42 ? 803 SER A OG 1 ATOM 6401 N N . THR A 1 804 ? -13.908 20.234 35.633 1.00 27.54 ? 804 THR A N 1 ATOM 6402 C CA . THR A 1 804 ? -12.617 20.845 35.296 1.00 26.92 ? 804 THR A CA 1 ATOM 6403 C C . THR A 1 804 ? -12.058 20.440 33.920 1.00 26.04 ? 804 THR A C 1 ATOM 6404 O O . THR A 1 804 ? -10.862 20.632 33.630 1.00 26.68 ? 804 THR A O 1 ATOM 6405 C CB . THR A 1 804 ? -11.601 20.613 36.407 1.00 27.18 ? 804 THR A CB 1 ATOM 6406 O OG1 . THR A 1 804 ? -11.564 19.220 36.719 1.00 28.64 ? 804 THR A OG1 1 ATOM 6407 C CG2 . THR A 1 804 ? -12.006 21.381 37.647 1.00 27.81 ? 804 THR A CG2 1 ATOM 6408 N N . TYR A 1 805 ? -12.926 19.876 33.090 1.00 24.09 ? 805 TYR A N 1 ATOM 6409 C CA . TYR A 1 805 ? -12.624 19.601 31.703 1.00 24.47 ? 805 TYR A CA 1 ATOM 6410 C C . TYR A 1 805 ? -13.830 19.912 30.846 1.00 24.99 ? 805 TYR A C 1 ATOM 6411 O O . TYR A 1 805 ? -14.935 19.395 31.098 1.00 25.29 ? 805 TYR A O 1 ATOM 6412 C CB . TYR A 1 805 ? -12.203 18.141 31.485 1.00 23.41 ? 805 TYR A CB 1 ATOM 6413 C CG . TYR A 1 805 ? -11.883 17.815 30.035 1.00 23.86 ? 805 TYR A CG 1 ATOM 6414 C CD1 . TYR A 1 805 ? -10.705 18.286 29.428 1.00 22.00 ? 805 TYR A CD1 1 ATOM 6415 C CD2 . TYR A 1 805 ? -12.757 17.050 29.271 1.00 20.78 ? 805 TYR A CD2 1 ATOM 6416 C CE1 . TYR A 1 805 ? -10.418 17.987 28.091 1.00 21.22 ? 805 TYR A CE1 1 ATOM 6417 C CE2 . TYR A 1 805 ? -12.484 16.752 27.964 1.00 20.50 ? 805 TYR A CE2 1 ATOM 6418 C CZ . TYR A 1 805 ? -11.316 17.208 27.377 1.00 20.39 ? 805 TYR A CZ 1 ATOM 6419 O OH . TYR A 1 805 ? -11.077 16.901 26.070 1.00 21.19 ? 805 TYR A OH 1 ATOM 6420 N N . LYS A 1 806 ? -13.622 20.776 29.857 1.00 25.47 ? 806 LYS A N 1 ATOM 6421 C CA . LYS A 1 806 ? -14.635 21.030 28.847 1.00 25.93 ? 806 LYS A CA 1 ATOM 6422 C C . LYS A 1 806 ? -14.128 20.566 27.493 1.00 25.21 ? 806 LYS A C 1 ATOM 6423 O O . LYS A 1 806 ? -13.157 21.097 26.966 1.00 25.56 ? 806 LYS A O 1 ATOM 6424 C CB . LYS A 1 806 ? -15.080 22.508 28.812 1.00 27.30 ? 806 LYS A CB 1 ATOM 6425 C CG . LYS A 1 806 ? -16.177 22.773 27.768 1.00 27.80 ? 806 LYS A CG 1 ATOM 6426 C CD . LYS A 1 806 ? -17.428 23.388 28.408 1.00 30.79 ? 806 LYS A CD 1 ATOM 6427 C CE . LYS A 1 806 ? -18.547 23.606 27.387 1.00 31.08 ? 806 LYS A CE 1 ATOM 6428 N NZ . LYS A 1 806 ? -19.661 24.472 27.898 1.00 33.80 ? 806 LYS A NZ 1 ATOM 6429 N N . ASP A 1 807 ? -14.801 19.555 26.959 1.00 23.66 ? 807 ASP A N 1 ATOM 6430 C CA . ASP A 1 807 ? -14.537 19.006 25.655 1.00 23.29 ? 807 ASP A CA 1 ATOM 6431 C C . ASP A 1 807 ? -14.721 20.075 24.567 1.00 23.21 ? 807 ASP A C 1 ATOM 6432 O O . ASP A 1 807 ? -15.733 20.768 24.538 1.00 22.37 ? 807 ASP A O 1 ATOM 6433 C CB . ASP A 1 807 ? -15.451 17.792 25.426 1.00 23.27 ? 807 ASP A CB 1 ATOM 6434 C CG . ASP A 1 807 ? -15.097 17.007 24.174 1.00 24.78 ? 807 ASP A CG 1 ATOM 6435 O OD1 . ASP A 1 807 ? -15.293 17.553 23.075 1.00 26.59 ? 807 ASP A OD1 1 ATOM 6436 O OD2 . ASP A 1 807 ? -14.655 15.840 24.285 1.00 25.25 ? 807 ASP A OD2 1 ATOM 6437 N N . PRO A 1 808 ? -13.723 20.221 23.662 1.00 22.93 ? 808 PRO A N 1 ATOM 6438 C CA . PRO A 1 808 ? -13.800 21.303 22.679 1.00 22.40 ? 808 PRO A CA 1 ATOM 6439 C C . PRO A 1 808 ? -14.772 21.079 21.517 1.00 21.60 ? 808 PRO A C 1 ATOM 6440 O O . PRO A 1 808 ? -14.973 21.992 20.704 1.00 20.75 ? 808 PRO A O 1 ATOM 6441 C CB . PRO A 1 808 ? -12.370 21.369 22.153 1.00 22.40 ? 808 PRO A CB 1 ATOM 6442 C CG . PRO A 1 808 ? -11.909 19.946 22.236 1.00 23.07 ? 808 PRO A CG 1 ATOM 6443 C CD . PRO A 1 808 ? -12.483 19.440 23.521 1.00 22.98 ? 808 PRO A CD 1 ATOM 6444 N N . ASN A 1 809 ? -15.376 19.891 21.449 1.00 21.72 ? 809 ASN A N 1 ATOM 6445 C CA . ASN A 1 809 ? -16.214 19.503 20.328 1.00 21.24 ? 809 ASN A CA 1 ATOM 6446 C C . ASN A 1 809 ? -17.722 19.767 20.496 1.00 21.70 ? 809 ASN A C 1 ATOM 6447 O O . ASN A 1 809 ? -18.524 19.149 19.803 1.00 21.60 ? 809 ASN A O 1 ATOM 6448 C CB . ASN A 1 809 ? -15.993 18.037 19.987 1.00 21.21 ? 809 ASN A CB 1 ATOM 6449 C CG . ASN A 1 809 ? -14.561 17.750 19.524 1.00 22.09 ? 809 ASN A CG 1 ATOM 6450 O OD1 . ASN A 1 809 ? -13.869 16.928 20.109 1.00 24.71 ? 809 ASN A OD1 1 ATOM 6451 N ND2 . ASN A 1 809 ? -14.122 18.443 18.497 1.00 22.16 ? 809 ASN A ND2 1 ATOM 6452 N N . ASN A 1 810 ? -18.064 20.675 21.393 1.00 21.44 ? 810 ASN A N 1 ATOM 6453 C CA . ASN A 1 810 ? -19.462 21.051 21.704 1.00 23.08 ? 810 ASN A CA 1 ATOM 6454 C C . ASN A 1 810 ? -20.410 19.872 21.800 1.00 21.88 ? 810 ASN A C 1 ATOM 6455 O O . ASN A 1 810 ? -21.326 19.717 20.993 1.00 21.82 ? 810 ASN A O 1 ATOM 6456 C CB . ASN A 1 810 ? -20.017 22.087 20.721 1.00 24.28 ? 810 ASN A CB 1 ATOM 6457 C CG . ASN A 1 810 ? -21.166 22.906 21.319 1.00 27.50 ? 810 ASN A CG 1 ATOM 6458 O OD1 . ASN A 1 810 ? -21.044 23.504 22.413 1.00 32.52 ? 810 ASN A OD1 1 ATOM 6459 N ND2 . ASN A 1 810 ? -22.281 22.947 20.596 1.00 32.20 ? 810 ASN A ND2 1 ATOM 6460 N N . LEU A 1 811 ? -20.149 19.031 22.791 1.00 20.89 ? 811 LEU A N 1 ATOM 6461 C CA . LEU A 1 811 ? -20.870 17.792 22.938 1.00 19.71 ? 811 LEU A CA 1 ATOM 6462 C C . LEU A 1 811 ? -22.088 18.107 23.743 1.00 18.60 ? 811 LEU A C 1 ATOM 6463 O O . LEU A 1 811 ? -22.040 18.927 24.661 1.00 17.91 ? 811 LEU A O 1 ATOM 6464 C CB . LEU A 1 811 ? -20.040 16.740 23.662 1.00 18.48 ? 811 LEU A CB 1 ATOM 6465 C CG . LEU A 1 811 ? -18.692 16.321 23.039 1.00 19.49 ? 811 LEU A CG 1 ATOM 6466 C CD1 . LEU A 1 811 ? -18.008 15.263 23.909 1.00 17.54 ? 811 LEU A CD1 1 ATOM 6467 C CD2 . LEU A 1 811 ? -18.939 15.790 21.647 1.00 16.50 ? 811 LEU A CD2 1 ATOM 6468 N N . ALA A 1 812 ? -23.160 17.406 23.429 1.00 18.01 ? 812 ALA A N 1 ATOM 6469 C CA . ALA A 1 812 ? -24.411 17.641 24.128 1.00 18.78 ? 812 ALA A CA 1 ATOM 6470 C C . ALA A 1 812 ? -25.256 16.402 23.976 1.00 18.30 ? 812 ALA A C 1 ATOM 6471 O O . ALA A 1 812 ? -25.249 15.760 22.920 1.00 18.43 ? 812 ALA A O 1 ATOM 6472 C CB . ALA A 1 812 ? -25.137 18.833 23.521 1.00 18.16 ? 812 ALA A CB 1 ATOM 6473 N N . PHE A 1 813 ? -25.957 16.058 25.036 1.00 18.89 ? 813 PHE A N 1 ATOM 6474 C CA . PHE A 1 813 ? -27.076 15.111 24.924 1.00 19.75 ? 813 PHE A CA 1 ATOM 6475 C C . PHE A 1 813 ? -28.100 15.732 23.991 1.00 20.67 ? 813 PHE A C 1 ATOM 6476 O O . PHE A 1 813 ? -28.613 16.822 24.272 1.00 22.27 ? 813 PHE A O 1 ATOM 6477 C CB . PHE A 1 813 ? -27.662 14.782 26.306 1.00 19.38 ? 813 PHE A CB 1 ATOM 6478 C CG . PHE A 1 813 ? -26.630 14.344 27.305 1.00 19.29 ? 813 PHE A CG 1 ATOM 6479 C CD1 . PHE A 1 813 ? -26.106 13.055 27.270 1.00 18.00 ? 813 PHE A CD1 1 ATOM 6480 C CD2 . PHE A 1 813 ? -26.139 15.236 28.250 1.00 21.70 ? 813 PHE A CD2 1 ATOM 6481 C CE1 . PHE A 1 813 ? -25.110 12.660 28.155 1.00 16.33 ? 813 PHE A CE1 1 ATOM 6482 C CE2 . PHE A 1 813 ? -25.137 14.842 29.148 1.00 21.46 ? 813 PHE A CE2 1 ATOM 6483 C CZ . PHE A 1 813 ? -24.634 13.554 29.106 1.00 18.73 ? 813 PHE A CZ 1 ATOM 6484 N N . ASN A 1 814 ? -28.364 15.087 22.857 1.00 21.59 ? 814 ASN A N 1 ATOM 6485 C CA . ASN A 1 814 ? -29.446 15.538 21.962 1.00 22.54 ? 814 ASN A CA 1 ATOM 6486 C C . ASN A 1 814 ? -30.589 14.551 21.853 1.00 22.75 ? 814 ASN A C 1 ATOM 6487 O O . ASN A 1 814 ? -31.469 14.717 21.020 1.00 23.02 ? 814 ASN A O 1 ATOM 6488 C CB . ASN A 1 814 ? -28.918 15.868 20.559 1.00 22.98 ? 814 ASN A CB 1 ATOM 6489 C CG . ASN A 1 814 ? -28.524 14.640 19.794 1.00 23.70 ? 814 ASN A CG 1 ATOM 6490 O OD1 . ASN A 1 814 ? -28.327 13.579 20.372 1.00 25.88 ? 814 ASN A OD1 1 ATOM 6491 N ND2 . ASN A 1 814 ? -28.427 14.763 18.471 1.00 28.39 ? 814 ASN A ND2 1 ATOM 6492 N N . GLU A 1 815 ? -30.545 13.491 22.661 1.00 23.38 ? 815 GLU A N 1 ATOM 6493 C CA . GLU A 1 815 ? -31.632 12.496 22.701 1.00 23.79 ? 815 GLU A CA 1 ATOM 6494 C C . GLU A 1 815 ? -31.724 11.908 24.109 1.00 23.41 ? 815 GLU A C 1 ATOM 6495 O O . GLU A 1 815 ? -30.683 11.584 24.731 1.00 22.94 ? 815 GLU A O 1 ATOM 6496 C CB . GLU A 1 815 ? -31.476 11.378 21.632 1.00 23.77 ? 815 GLU A CB 1 ATOM 6497 C CG . GLU A 1 815 ? -32.712 10.465 21.530 1.00 24.69 ? 815 GLU A CG 1 ATOM 6498 C CD . GLU A 1 815 ? -32.653 9.307 20.513 1.00 26.53 ? 815 GLU A CD 1 ATOM 6499 O OE1 . GLU A 1 815 ? -32.548 9.545 19.291 1.00 31.42 ? 815 GLU A OE1 1 ATOM 6500 O OE2 . GLU A 1 815 ? -32.800 8.128 20.934 1.00 32.46 ? 815 GLU A OE2 1 ATOM 6501 N N . ILE A 1 816 ? -32.959 11.825 24.623 1.00 22.50 ? 816 ILE A N 1 ATOM 6502 C CA . ILE A 1 816 ? -33.267 11.087 25.853 1.00 21.15 ? 816 ILE A CA 1 ATOM 6503 C C . ILE A 1 816 ? -34.353 10.037 25.576 1.00 21.83 ? 816 ILE A C 1 ATOM 6504 O O . ILE A 1 816 ? -35.461 10.360 25.131 1.00 21.49 ? 816 ILE A O 1 ATOM 6505 C CB . ILE A 1 816 ? -33.654 12.018 27.033 1.00 21.20 ? 816 ILE A CB 1 ATOM 6506 C CG1 . ILE A 1 816 ? -32.592 13.114 27.249 1.00 21.15 ? 816 ILE A CG1 1 ATOM 6507 C CG2 . ILE A 1 816 ? -33.835 11.212 28.313 1.00 20.44 ? 816 ILE A CG2 1 ATOM 6508 C CD1 . ILE A 1 816 ? -33.003 14.228 28.196 1.00 20.14 ? 816 ILE A CD1 1 ATOM 6509 N N . LYS A 1 817 ? -34.015 8.775 25.823 1.00 20.71 ? 817 LYS A N 1 ATOM 6510 C CA . LYS A 1 817 ? -34.940 7.691 25.657 1.00 21.08 ? 817 LYS A CA 1 ATOM 6511 C C . LYS A 1 817 ? -35.306 7.243 27.068 1.00 20.74 ? 817 LYS A C 1 ATOM 6512 O O . LYS A 1 817 ? -34.425 6.927 27.848 1.00 21.12 ? 817 LYS A O 1 ATOM 6513 C CB . LYS A 1 817 ? -34.270 6.558 24.877 1.00 20.65 ? 817 LYS A CB 1 ATOM 6514 C CG . LYS A 1 817 ? -35.148 5.380 24.585 1.00 22.69 ? 817 LYS A CG 1 ATOM 6515 C CD . LYS A 1 817 ? -34.377 4.401 23.745 1.00 24.17 ? 817 LYS A CD 1 ATOM 6516 C CE . LYS A 1 817 ? -35.306 3.587 22.889 1.00 27.08 ? 817 LYS A CE 1 ATOM 6517 N NZ . LYS A 1 817 ? -34.505 2.587 22.084 1.00 30.33 ? 817 LYS A NZ 1 ATOM 6518 N N . ILE A 1 818 ? -36.604 7.247 27.382 1.00 19.47 ? 818 ILE A N 1 ATOM 6519 C CA . ILE A 1 818 ? -37.103 6.822 28.699 1.00 19.34 ? 818 ILE A CA 1 ATOM 6520 C C . ILE A 1 818 ? -37.833 5.508 28.501 1.00 19.12 ? 818 ILE A C 1 ATOM 6521 O O . ILE A 1 818 ? -38.710 5.414 27.643 1.00 17.76 ? 818 ILE A O 1 ATOM 6522 C CB . ILE A 1 818 ? -38.055 7.902 29.376 1.00 19.42 ? 818 ILE A CB 1 ATOM 6523 C CG1 . ILE A 1 818 ? -37.380 9.283 29.379 1.00 18.57 ? 818 ILE A CG1 1 ATOM 6524 C CG2 . ILE A 1 818 ? -38.403 7.495 30.790 1.00 18.25 ? 818 ILE A CG2 1 ATOM 6525 C CD1 . ILE A 1 818 ? -38.312 10.487 29.623 1.00 18.89 ? 818 ILE A CD1 1 ATOM 6526 N N . LEU A 1 819 ? -37.427 4.497 29.270 1.00 18.84 ? 819 LEU A N 1 ATOM 6527 C CA . LEU A 1 819 ? -38.002 3.155 29.204 1.00 19.98 ? 819 LEU A CA 1 ATOM 6528 C C . LEU A 1 819 ? -39.003 2.947 30.349 1.00 19.74 ? 819 LEU A C 1 ATOM 6529 O O . LEU A 1 819 ? -38.786 3.432 31.449 1.00 19.71 ? 819 LEU A O 1 ATOM 6530 C CB . LEU A 1 819 ? -36.893 2.080 29.266 1.00 18.93 ? 819 LEU A CB 1 ATOM 6531 C CG . LEU A 1 819 ? -35.777 2.258 28.215 1.00 19.89 ? 819 LEU A CG 1 ATOM 6532 C CD1 . LEU A 1 819 ? -34.779 1.114 28.236 1.00 14.29 ? 819 LEU A CD1 1 ATOM 6533 C CD2 . LEU A 1 819 ? -36.434 2.385 26.825 1.00 17.87 ? 819 LEU A CD2 1 ATOM 6534 N N . GLY A 1 820 ? -40.074 2.214 30.080 1.00 20.19 ? 820 GLY A N 1 ATOM 6535 C CA . GLY A 1 820 ? -41.116 1.927 31.111 1.00 20.37 ? 820 GLY A CA 1 ATOM 6536 C C . GLY A 1 820 ? -41.837 3.159 31.609 1.00 21.74 ? 820 GLY A C 1 ATOM 6537 O O . GLY A 1 820 ? -42.119 3.291 32.803 1.00 22.08 ? 820 GLY A O 1 ATOM 6538 N N . THR A 1 821 ? -42.168 4.068 30.698 1.00 21.78 ? 821 THR A N 1 ATOM 6539 C CA . THR A 1 821 ? -42.843 5.299 31.104 1.00 23.21 ? 821 THR A CA 1 ATOM 6540 C C . THR A 1 821 ? -44.258 5.410 30.518 1.00 23.64 ? 821 THR A C 1 ATOM 6541 O O . THR A 1 821 ? -44.559 4.858 29.465 1.00 23.17 ? 821 THR A O 1 ATOM 6542 C CB . THR A 1 821 ? -42.020 6.546 30.752 1.00 23.35 ? 821 THR A CB 1 ATOM 6543 O OG1 . THR A 1 821 ? -42.724 7.723 31.176 1.00 24.37 ? 821 THR A OG1 1 ATOM 6544 C CG2 . THR A 1 821 ? -41.741 6.616 29.241 1.00 22.60 ? 821 THR A CG2 1 ATOM 6545 N N . GLU A 1 822 ? -45.133 6.115 31.219 1.00 24.91 ? 822 GLU A N 1 ATOM 6546 C CA . GLU A 1 822 ? -46.410 6.510 30.615 1.00 26.42 ? 822 GLU A CA 1 ATOM 6547 C C . GLU A 1 822 ? -46.150 7.723 29.721 1.00 26.68 ? 822 GLU A C 1 ATOM 6548 O O . GLU A 1 822 ? -45.093 8.338 29.832 1.00 26.39 ? 822 GLU A O 1 ATOM 6549 C CB . GLU A 1 822 ? -47.461 6.776 31.706 1.00 27.07 ? 822 GLU A CB 1 ATOM 6550 C CG . GLU A 1 822 ? -47.860 5.496 32.465 1.00 28.93 ? 822 GLU A CG 1 ATOM 6551 C CD . GLU A 1 822 ? -48.574 4.469 31.574 1.00 34.57 ? 822 GLU A CD 1 ATOM 6552 O OE1 . GLU A 1 822 ? -49.424 4.866 30.746 1.00 34.84 ? 822 GLU A OE1 1 ATOM 6553 O OE2 . GLU A 1 822 ? -48.286 3.256 31.704 1.00 36.81 ? 822 GLU A OE2 1 ATOM 6554 N N . GLU A 1 823 ? -47.075 8.078 28.825 1.00 27.87 ? 823 GLU A N 1 ATOM 6555 C CA . GLU A 1 823 ? -46.799 9.203 27.909 1.00 28.88 ? 823 GLU A CA 1 ATOM 6556 C C . GLU A 1 823 ? -46.398 10.507 28.627 1.00 29.89 ? 823 GLU A C 1 ATOM 6557 O O . GLU A 1 823 ? -47.193 11.032 29.420 1.00 29.67 ? 823 GLU A O 1 ATOM 6558 C CB . GLU A 1 823 ? -47.974 9.444 26.968 1.00 29.68 ? 823 GLU A CB 1 ATOM 6559 C CG . GLU A 1 823 ? -47.678 10.471 25.903 1.00 30.74 ? 823 GLU A CG 1 ATOM 6560 C CD . GLU A 1 823 ? -48.663 10.454 24.760 1.00 34.72 ? 823 GLU A CD 1 ATOM 6561 O OE1 . GLU A 1 823 ? -49.772 9.878 24.911 1.00 36.31 ? 823 GLU A OE1 1 ATOM 6562 O OE2 . GLU A 1 823 ? -48.322 11.033 23.700 1.00 36.03 ? 823 GLU A OE2 1 ATOM 6563 N N . PRO A 1 824 ? -45.166 11.026 28.369 1.00 29.71 ? 824 PRO A N 1 ATOM 6564 C CA . PRO A 1 824 ? -44.802 12.322 28.928 1.00 30.78 ? 824 PRO A CA 1 ATOM 6565 C C . PRO A 1 824 ? -45.481 13.449 28.137 1.00 32.13 ? 824 PRO A C 1 ATOM 6566 O O . PRO A 1 824 ? -45.648 13.342 26.913 1.00 33.04 ? 824 PRO A O 1 ATOM 6567 C CB . PRO A 1 824 ? -43.265 12.402 28.763 1.00 30.54 ? 824 PRO A CB 1 ATOM 6568 C CG . PRO A 1 824 ? -42.842 11.183 28.037 1.00 29.79 ? 824 PRO A CG 1 ATOM 6569 C CD . PRO A 1 824 ? -44.083 10.460 27.543 1.00 30.44 ? 824 PRO A CD 1 ATOM 6570 N N . SER A 1 825 ? -45.894 14.498 28.843 1.00 32.66 ? 825 SER A N 1 ATOM 6571 C CA . SER A 1 825 ? -46.496 15.688 28.230 1.00 33.27 ? 825 SER A CA 1 ATOM 6572 C C . SER A 1 825 ? -45.853 16.909 28.871 1.00 33.29 ? 825 SER A C 1 ATOM 6573 O O . SER A 1 825 ? -45.247 16.784 29.934 1.00 33.58 ? 825 SER A O 1 ATOM 6574 C CB . SER A 1 825 ? -48.018 15.697 28.447 1.00 33.50 ? 825 SER A CB 1 ATOM 6575 O OG . SER A 1 825 ? -48.349 16.017 29.788 1.00 33.92 ? 825 SER A OG 1 ATOM 6576 N N . ASN A 1 826 ? -45.995 18.071 28.231 1.00 33.24 ? 826 ASN A N 1 ATOM 6577 C CA . ASN A 1 826 ? -45.394 19.346 28.672 1.00 33.00 ? 826 ASN A CA 1 ATOM 6578 C C . ASN A 1 826 ? -43.908 19.222 29.064 1.00 32.04 ? 826 ASN A C 1 ATOM 6579 O O . ASN A 1 826 ? -43.537 19.586 30.177 1.00 31.90 ? 826 ASN A O 1 ATOM 6580 C CB . ASN A 1 826 ? -46.157 19.991 29.846 1.00 33.24 ? 826 ASN A CB 1 ATOM 6581 C CG . ASN A 1 826 ? -47.682 20.063 29.638 1.00 36.28 ? 826 ASN A CG 1 ATOM 6582 O OD1 . ASN A 1 826 ? -48.202 20.028 28.508 1.00 39.16 ? 826 ASN A OD1 1 ATOM 6583 N ND2 . ASN A 1 826 ? -48.402 20.171 30.750 1.00 36.94 ? 826 ASN A ND2 1 ATOM 6584 N N . VAL A 1 827 ? -43.072 18.715 28.163 1.00 31.02 ? 827 VAL A N 1 ATOM 6585 C CA . VAL A 1 827 ? -41.641 18.579 28.460 1.00 29.66 ? 827 VAL A CA 1 ATOM 6586 C C . VAL A 1 827 ? -40.936 19.946 28.489 1.00 29.67 ? 827 VAL A C 1 ATOM 6587 O O . VAL A 1 827 ? -40.887 20.682 27.496 1.00 29.04 ? 827 VAL A O 1 ATOM 6588 C CB . VAL A 1 827 ? -40.950 17.534 27.545 1.00 29.50 ? 827 VAL A CB 1 ATOM 6589 C CG1 . VAL A 1 827 ? -39.497 17.321 27.962 1.00 27.58 ? 827 VAL A CG1 1 ATOM 6590 C CG2 . VAL A 1 827 ? -41.704 16.208 27.614 1.00 28.29 ? 827 VAL A CG2 1 ATOM 6591 N N . THR A 1 828 ? -40.431 20.286 29.667 1.00 30.54 ? 828 THR A N 1 ATOM 6592 C CA . THR A 1 828 ? -39.723 21.544 29.927 1.00 31.22 ? 828 THR A CA 1 ATOM 6593 C C . THR A 1 828 ? -38.262 21.259 30.296 1.00 31.40 ? 828 THR A C 1 ATOM 6594 O O . THR A 1 828 ? -37.977 20.318 31.040 1.00 30.57 ? 828 THR A O 1 ATOM 6595 C CB . THR A 1 828 ? -40.376 22.314 31.100 1.00 31.59 ? 828 THR A CB 1 ATOM 6596 O OG1 . THR A 1 828 ? -41.794 22.455 30.864 1.00 34.33 ? 828 THR A OG1 1 ATOM 6597 C CG2 . THR A 1 828 ? -39.767 23.698 31.226 1.00 32.21 ? 828 THR A CG2 1 ATOM 6598 N N . VAL A 1 829 ? -37.355 22.089 29.791 1.00 31.38 ? 829 VAL A N 1 ATOM 6599 C CA . VAL A 1 829 ? -35.922 21.928 30.024 1.00 32.39 ? 829 VAL A CA 1 ATOM 6600 C C . VAL A 1 829 ? -35.450 23.221 30.655 1.00 33.06 ? 829 VAL A C 1 ATOM 6601 O O . VAL A 1 829 ? -35.568 24.282 30.049 1.00 32.94 ? 829 VAL A O 1 ATOM 6602 C CB . VAL A 1 829 ? -35.151 21.684 28.698 1.00 31.86 ? 829 VAL A CB 1 ATOM 6603 C CG1 . VAL A 1 829 ? -33.657 21.557 28.941 1.00 32.61 ? 829 VAL A CG1 1 ATOM 6604 C CG2 . VAL A 1 829 ? -35.687 20.477 27.978 1.00 30.78 ? 829 VAL A CG2 1 ATOM 6605 N N . LYS A 1 830 ? -34.964 23.146 31.885 1.00 33.93 ? 830 LYS A N 1 ATOM 6606 C CA . LYS A 1 830 ? -34.462 24.334 32.557 1.00 35.76 ? 830 LYS A CA 1 ATOM 6607 C C . LYS A 1 830 ? -32.960 24.232 32.784 1.00 36.58 ? 830 LYS A C 1 ATOM 6608 O O . LYS A 1 830 ? -32.452 23.159 33.065 1.00 35.87 ? 830 LYS A O 1 ATOM 6609 C CB . LYS A 1 830 ? -35.218 24.575 33.865 1.00 35.62 ? 830 LYS A CB 1 ATOM 6610 C CG . LYS A 1 830 ? -36.735 24.716 33.654 1.00 36.68 ? 830 LYS A CG 1 ATOM 6611 C CD . LYS A 1 830 ? -37.455 25.330 34.850 1.00 36.71 ? 830 LYS A CD 1 ATOM 6612 C CE . LYS A 1 830 ? -38.980 25.312 34.623 1.00 39.82 ? 830 LYS A CE 1 ATOM 6613 N NZ . LYS A 1 830 ? -39.756 25.842 35.795 1.00 42.06 ? 830 LYS A NZ 1 ATOM 6614 N N . HIS A 1 831 ? -32.273 25.358 32.627 1.00 38.92 ? 831 HIS A N 1 ATOM 6615 C CA . HIS A 1 831 ? -30.849 25.497 32.876 1.00 41.05 ? 831 HIS A CA 1 ATOM 6616 C C . HIS A 1 831 ? -30.707 26.458 34.052 1.00 42.76 ? 831 HIS A C 1 ATOM 6617 O O . HIS A 1 831 ? -30.944 27.655 33.899 1.00 42.96 ? 831 HIS A O 1 ATOM 6618 C CB . HIS A 1 831 ? -30.184 26.090 31.635 1.00 41.34 ? 831 HIS A CB 1 ATOM 6619 C CG . HIS A 1 831 ? -28.688 26.032 31.643 1.00 42.45 ? 831 HIS A CG 1 ATOM 6620 N ND1 . HIS A 1 831 ? -27.930 26.347 30.533 1.00 43.83 ? 831 HIS A ND1 1 ATOM 6621 C CD2 . HIS A 1 831 ? -27.808 25.687 32.614 1.00 43.87 ? 831 HIS A CD2 1 ATOM 6622 C CE1 . HIS A 1 831 ? -26.647 26.208 30.825 1.00 44.69 ? 831 HIS A CE1 1 ATOM 6623 N NE2 . HIS A 1 831 ? -26.547 25.807 32.080 1.00 44.83 ? 831 HIS A NE2 1 ATOM 6624 N N . ASN A 1 832 ? -30.329 25.931 35.220 1.00 44.99 ? 832 ASN A N 1 ATOM 6625 C CA . ASN A 1 832 ? -30.346 26.676 36.494 1.00 46.72 ? 832 ASN A CA 1 ATOM 6626 C C . ASN A 1 832 ? -31.688 27.364 36.741 1.00 47.91 ? 832 ASN A C 1 ATOM 6627 O O . ASN A 1 832 ? -31.743 28.560 37.038 1.00 48.45 ? 832 ASN A O 1 ATOM 6628 C CB . ASN A 1 832 ? -29.192 27.687 36.581 1.00 46.98 ? 832 ASN A CB 1 ATOM 6629 C CG . ASN A 1 832 ? -27.827 27.051 36.344 1.00 47.61 ? 832 ASN A CG 1 ATOM 6630 O OD1 . ASN A 1 832 ? -27.466 26.060 36.981 1.00 48.56 ? 832 ASN A OD1 1 ATOM 6631 N ND2 . ASN A 1 832 ? -27.059 27.632 35.431 1.00 48.45 ? 832 ASN A ND2 1 ATOM 6632 N N . GLY A 1 833 ? -32.771 26.605 36.590 1.00 49.00 ? 833 GLY A N 1 ATOM 6633 C CA . GLY A 1 833 ? -34.117 27.114 36.836 1.00 50.29 ? 833 GLY A CA 1 ATOM 6634 C C . GLY A 1 833 ? -34.670 28.014 35.748 1.00 51.18 ? 833 GLY A C 1 ATOM 6635 O O . GLY A 1 833 ? -35.815 28.452 35.836 1.00 51.35 ? 833 GLY A O 1 ATOM 6636 N N . VAL A 1 834 ? -33.864 28.272 34.720 1.00 51.87 ? 834 VAL A N 1 ATOM 6637 C CA . VAL A 1 834 ? -34.226 29.190 33.641 1.00 52.67 ? 834 VAL A CA 1 ATOM 6638 C C . VAL A 1 834 ? -34.723 28.450 32.389 1.00 53.37 ? 834 VAL A C 1 ATOM 6639 O O . VAL A 1 834 ? -33.940 27.776 31.714 1.00 53.03 ? 834 VAL A O 1 ATOM 6640 C CB . VAL A 1 834 ? -33.035 30.103 33.260 1.00 52.60 ? 834 VAL A CB 1 ATOM 6641 C CG1 . VAL A 1 834 ? -33.499 31.263 32.391 1.00 52.73 ? 834 VAL A CG1 1 ATOM 6642 C CG2 . VAL A 1 834 ? -32.316 30.613 34.515 1.00 52.97 ? 834 VAL A CG2 1 ATOM 6643 N N . PRO A 1 835 ? -36.036 28.558 32.089 1.00 54.23 ? 835 PRO A N 1 ATOM 6644 C CA . PRO A 1 835 ? -36.588 28.033 30.848 1.00 54.87 ? 835 PRO A CA 1 ATOM 6645 C C . PRO A 1 835 ? -36.820 29.129 29.800 1.00 55.93 ? 835 PRO A C 1 ATOM 6646 O O . PRO A 1 835 ? -37.506 30.123 30.097 1.00 56.11 ? 835 PRO A O 1 ATOM 6647 C CB . PRO A 1 835 ? -37.944 27.484 31.299 1.00 55.24 ? 835 PRO A CB 1 ATOM 6648 C CG . PRO A 1 835 ? -38.341 28.376 32.515 1.00 54.45 ? 835 PRO A CG 1 ATOM 6649 C CD . PRO A 1 835 ? -37.096 29.131 32.945 1.00 54.25 ? 835 PRO A CD 1 ATOM 6650 N N . SER A 1 836 ? -36.266 29.000 28.593 1.00 56.59 ? 836 SER A N 1 ATOM 6651 C CA . SER A 1 836 ? -35.271 28.010 28.195 1.00 57.12 ? 836 SER A CA 1 ATOM 6652 C C . SER A 1 836 ? -34.706 28.455 26.841 1.00 57.58 ? 836 SER A C 1 ATOM 6653 O O . SER A 1 836 ? -35.351 28.308 25.792 1.00 57.53 ? 836 SER A O 1 ATOM 6654 C CB . SER A 1 836 ? -35.871 26.610 28.062 1.00 57.27 ? 836 SER A CB 1 ATOM 6655 O OG . SER A 1 836 ? -34.947 25.731 27.440 1.00 56.96 ? 836 SER A OG 1 ATOM 6656 N N . SER A 1 839 ? -39.357 24.053 23.243 1.00 30.07 ? 839 SER A N 1 ATOM 6657 C CA . SER A 1 839 ? -40.026 22.782 23.507 1.00 29.94 ? 839 SER A CA 1 ATOM 6658 C C . SER A 1 839 ? -39.361 21.649 22.722 1.00 28.62 ? 839 SER A C 1 ATOM 6659 O O . SER A 1 839 ? -39.288 21.704 21.481 1.00 29.54 ? 839 SER A O 1 ATOM 6660 C CB . SER A 1 839 ? -41.527 22.868 23.174 1.00 30.69 ? 839 SER A CB 1 ATOM 6661 O OG . SER A 1 839 ? -42.168 21.601 23.345 1.00 33.47 ? 839 SER A OG 1 ATOM 6662 N N . PRO A 1 840 ? -38.802 20.653 23.437 1.00 26.63 ? 840 PRO A N 1 ATOM 6663 C CA . PRO A 1 840 ? -38.268 19.475 22.776 1.00 25.22 ? 840 PRO A CA 1 ATOM 6664 C C . PRO A 1 840 ? -39.341 18.718 22.025 1.00 24.38 ? 840 PRO A C 1 ATOM 6665 O O . PRO A 1 840 ? -40.516 18.822 22.358 1.00 24.00 ? 840 PRO A O 1 ATOM 6666 C CB . PRO A 1 840 ? -37.793 18.610 23.935 1.00 24.59 ? 840 PRO A CB 1 ATOM 6667 C CG . PRO A 1 840 ? -38.428 19.164 25.128 1.00 26.34 ? 840 PRO A CG 1 ATOM 6668 C CD . PRO A 1 840 ? -38.554 20.607 24.885 1.00 26.50 ? 840 PRO A CD 1 ATOM 6669 N N . THR A 1 841 ? -38.917 17.943 21.035 1.00 23.09 ? 841 THR A N 1 ATOM 6670 C CA . THR A 1 841 ? -39.793 16.984 20.370 1.00 21.32 ? 841 THR A CA 1 ATOM 6671 C C . THR A 1 841 ? -39.889 15.716 21.211 1.00 21.23 ? 841 THR A C 1 ATOM 6672 O O . THR A 1 841 ? -38.889 15.242 21.743 1.00 20.25 ? 841 THR A O 1 ATOM 6673 C CB . THR A 1 841 ? -39.270 16.682 18.956 1.00 21.00 ? 841 THR A CB 1 ATOM 6674 O OG1 . THR A 1 841 ? -39.464 17.840 18.149 1.00 19.31 ? 841 THR A OG1 1 ATOM 6675 C CG2 . THR A 1 841 ? -39.997 15.506 18.305 1.00 20.97 ? 841 THR A CG2 1 ATOM 6676 N N . VAL A 1 842 ? -41.105 15.179 21.335 1.00 20.85 ? 842 VAL A N 1 ATOM 6677 C CA . VAL A 1 842 ? -41.345 13.958 22.099 1.00 21.19 ? 842 VAL A CA 1 ATOM 6678 C C . VAL A 1 842 ? -42.088 12.971 21.202 1.00 21.25 ? 842 VAL A C 1 ATOM 6679 O O . VAL A 1 842 ? -43.150 13.306 20.630 1.00 20.32 ? 842 VAL A O 1 ATOM 6680 C CB . VAL A 1 842 ? -42.155 14.239 23.422 1.00 22.22 ? 842 VAL A CB 1 ATOM 6681 C CG1 . VAL A 1 842 ? -42.413 12.959 24.192 1.00 21.59 ? 842 VAL A CG1 1 ATOM 6682 C CG2 . VAL A 1 842 ? -41.418 15.260 24.309 1.00 21.73 ? 842 VAL A CG2 1 ATOM 6683 N N . THR A 1 843 ? -41.485 11.792 21.029 1.00 19.94 ? 843 THR A N 1 ATOM 6684 C CA . THR A 1 843 ? -42.072 10.684 20.298 1.00 20.44 ? 843 THR A CA 1 ATOM 6685 C C . THR A 1 843 ? -42.448 9.613 21.319 1.00 20.50 ? 843 THR A C 1 ATOM 6686 O O . THR A 1 843 ? -41.662 9.305 22.220 1.00 20.63 ? 843 THR A O 1 ATOM 6687 C CB . THR A 1 843 ? -41.096 10.132 19.241 1.00 20.48 ? 843 THR A CB 1 ATOM 6688 O OG1 . THR A 1 843 ? -40.525 11.230 18.510 1.00 22.61 ? 843 THR A OG1 1 ATOM 6689 C CG2 . THR A 1 843 ? -41.802 9.218 18.269 1.00 21.00 ? 843 THR A CG2 1 ATOM 6690 N N . TYR A 1 844 ? -43.654 9.061 21.203 1.00 20.48 ? 844 TYR A N 1 ATOM 6691 C CA . TYR A 1 844 ? -44.102 8.091 22.191 1.00 20.41 ? 844 TYR A CA 1 ATOM 6692 C C . TYR A 1 844 ? -44.662 6.814 21.559 1.00 21.02 ? 844 TYR A C 1 ATOM 6693 O O . TYR A 1 844 ? -45.424 6.841 20.575 1.00 19.71 ? 844 TYR A O 1 ATOM 6694 C CB . TYR A 1 844 ? -45.072 8.733 23.236 1.00 20.60 ? 844 TYR A CB 1 ATOM 6695 C CG . TYR A 1 844 ? -45.445 7.771 24.351 1.00 19.91 ? 844 TYR A CG 1 ATOM 6696 C CD1 . TYR A 1 844 ? -44.487 7.341 25.268 1.00 22.28 ? 844 TYR A CD1 1 ATOM 6697 C CD2 . TYR A 1 844 ? -46.734 7.214 24.432 1.00 21.81 ? 844 TYR A CD2 1 ATOM 6698 C CE1 . TYR A 1 844 ? -44.807 6.417 26.273 1.00 22.19 ? 844 TYR A CE1 1 ATOM 6699 C CE2 . TYR A 1 844 ? -47.070 6.290 25.450 1.00 20.22 ? 844 TYR A CE2 1 ATOM 6700 C CZ . TYR A 1 844 ? -46.091 5.894 26.356 1.00 21.37 ? 844 TYR A CZ 1 ATOM 6701 O OH . TYR A 1 844 ? -46.394 4.991 27.365 1.00 20.36 ? 844 TYR A OH 1 ATOM 6702 N N . ASP A 1 845 ? -44.255 5.683 22.136 1.00 21.65 ? 845 ASP A N 1 ATOM 6703 C CA . ASP A 1 845 ? -44.715 4.388 21.712 1.00 22.32 ? 845 ASP A CA 1 ATOM 6704 C C . ASP A 1 845 ? -45.523 3.812 22.869 1.00 23.34 ? 845 ASP A C 1 ATOM 6705 O O . ASP A 1 845 ? -44.976 3.325 23.845 1.00 22.27 ? 845 ASP A O 1 ATOM 6706 C CB . ASP A 1 845 ? -43.528 3.490 21.307 1.00 22.88 ? 845 ASP A CB 1 ATOM 6707 C CG . ASP A 1 845 ? -43.964 2.145 20.738 1.00 23.91 ? 845 ASP A CG 1 ATOM 6708 O OD1 . ASP A 1 845 ? -44.898 1.540 21.272 1.00 28.54 ? 845 ASP A OD1 1 ATOM 6709 O OD2 . ASP A 1 845 ? -43.380 1.672 19.752 1.00 23.75 ? 845 ASP A OD2 1 ATOM 6710 N N . SER A 1 846 ? -46.849 3.872 22.736 1.00 24.23 ? 846 SER A N 1 ATOM 6711 C CA . SER A 1 846 ? -47.749 3.455 23.802 1.00 25.22 ? 846 SER A CA 1 ATOM 6712 C C . SER A 1 846 ? -47.759 1.957 24.038 1.00 25.19 ? 846 SER A C 1 ATOM 6713 O O . SER A 1 846 ? -47.992 1.524 25.156 1.00 25.79 ? 846 SER A O 1 ATOM 6714 C CB . SER A 1 846 ? -49.166 3.953 23.516 1.00 25.60 ? 846 SER A CB 1 ATOM 6715 O OG . SER A 1 846 ? -49.670 3.244 22.411 1.00 25.84 ? 846 SER A OG 1 ATOM 6716 N N . ASN A 1 847 ? -47.501 1.163 22.999 1.00 25.14 ? 847 ASN A N 1 ATOM 6717 C CA . ASN A 1 847 ? -47.398 -0.288 23.155 1.00 25.58 ? 847 ASN A CA 1 ATOM 6718 C C . ASN A 1 847 ? -46.188 -0.673 24.002 1.00 24.84 ? 847 ASN A C 1 ATOM 6719 O O . ASN A 1 847 ? -46.292 -1.460 24.950 1.00 25.10 ? 847 ASN A O 1 ATOM 6720 C CB . ASN A 1 847 ? -47.291 -0.987 21.793 1.00 26.04 ? 847 ASN A CB 1 ATOM 6721 C CG . ASN A 1 847 ? -47.262 -2.509 21.917 1.00 31.13 ? 847 ASN A CG 1 ATOM 6722 O OD1 . ASN A 1 847 ? -46.211 -3.158 21.725 1.00 33.81 ? 847 ASN A OD1 1 ATOM 6723 N ND2 . ASN A 1 847 ? -48.412 -3.093 22.285 1.00 34.57 ? 847 ASN A ND2 1 ATOM 6724 N N . LEU A 1 848 ? -45.042 -0.107 23.645 1.00 23.38 ? 848 LEU A N 1 ATOM 6725 C CA . LEU A 1 848 ? -43.777 -0.461 24.284 1.00 22.08 ? 848 LEU A CA 1 ATOM 6726 C C . LEU A 1 848 ? -43.511 0.295 25.575 1.00 21.31 ? 848 LEU A C 1 ATOM 6727 O O . LEU A 1 848 ? -42.611 -0.088 26.327 1.00 21.23 ? 848 LEU A O 1 ATOM 6728 C CB . LEU A 1 848 ? -42.637 -0.204 23.296 1.00 22.49 ? 848 LEU A CB 1 ATOM 6729 C CG . LEU A 1 848 ? -42.178 -1.422 22.495 1.00 23.62 ? 848 LEU A CG 1 ATOM 6730 C CD1 . LEU A 1 848 ? -43.288 -2.433 22.206 1.00 24.76 ? 848 LEU A CD1 1 ATOM 6731 C CD2 . LEU A 1 848 ? -41.508 -0.971 21.219 1.00 25.51 ? 848 LEU A CD2 1 ATOM 6732 N N . LYS A 1 849 ? -44.261 1.377 25.820 1.00 19.89 ? 849 LYS A N 1 ATOM 6733 C CA . LYS A 1 849 ? -44.011 2.293 26.951 1.00 19.50 ? 849 LYS A CA 1 ATOM 6734 C C . LYS A 1 849 ? -42.615 2.984 26.869 1.00 19.88 ? 849 LYS A C 1 ATOM 6735 O O . LYS A 1 849 ? -41.893 3.103 27.863 1.00 17.58 ? 849 LYS A O 1 ATOM 6736 C CB . LYS A 1 849 ? -44.203 1.564 28.291 1.00 19.50 ? 849 LYS A CB 1 ATOM 6737 C CG . LYS A 1 849 ? -45.556 0.838 28.425 1.00 20.08 ? 849 LYS A CG 1 ATOM 6738 C CD . LYS A 1 849 ? -46.692 1.848 28.437 1.00 18.74 ? 849 LYS A CD 1 ATOM 6739 C CE . LYS A 1 849 ? -48.067 1.154 28.478 1.00 24.32 ? 849 LYS A CE 1 ATOM 6740 N NZ . LYS A 1 849 ? -49.222 2.149 28.581 1.00 25.49 ? 849 LYS A NZ 1 ATOM 6741 N N . VAL A 1 850 ? -42.275 3.457 25.671 1.00 20.04 ? 850 VAL A N 1 ATOM 6742 C CA . VAL A 1 850 ? -41.020 4.148 25.409 1.00 19.96 ? 850 VAL A CA 1 ATOM 6743 C C . VAL A 1 850 ? -41.286 5.565 24.915 1.00 19.80 ? 850 VAL A C 1 ATOM 6744 O O . VAL A 1 850 ? -42.018 5.763 23.939 1.00 20.34 ? 850 VAL A O 1 ATOM 6745 C CB . VAL A 1 850 ? -40.202 3.379 24.336 1.00 19.72 ? 850 VAL A CB 1 ATOM 6746 C CG1 . VAL A 1 850 ? -38.831 4.069 24.032 1.00 20.30 ? 850 VAL A CG1 1 ATOM 6747 C CG2 . VAL A 1 850 ? -39.976 1.946 24.797 1.00 19.34 ? 850 VAL A CG2 1 ATOM 6748 N N . ALA A 1 851 ? -40.674 6.543 25.575 1.00 19.40 ? 851 ALA A N 1 ATOM 6749 C CA . ALA A 1 851 ? -40.652 7.920 25.092 1.00 19.09 ? 851 ALA A CA 1 ATOM 6750 C C . ALA A 1 851 ? -39.223 8.263 24.629 1.00 19.40 ? 851 ALA A C 1 ATOM 6751 O O . ALA A 1 851 ? -38.254 7.872 25.276 1.00 18.78 ? 851 ALA A O 1 ATOM 6752 C CB . ALA A 1 851 ? -41.096 8.872 26.201 1.00 18.82 ? 851 ALA A CB 1 ATOM 6753 N N . ILE A 1 852 ? -39.100 8.963 23.496 1.00 19.26 ? 852 ILE A N 1 ATOM 6754 C CA . ILE A 1 852 ? -37.815 9.531 23.055 1.00 19.04 ? 852 ILE A CA 1 ATOM 6755 C C . ILE A 1 852 ? -37.970 11.044 22.974 1.00 19.26 ? 852 ILE A C 1 ATOM 6756 O O . ILE A 1 852 ? -38.879 11.550 22.308 1.00 19.33 ? 852 ILE A O 1 ATOM 6757 C CB . ILE A 1 852 ? -37.313 8.963 21.692 1.00 18.58 ? 852 ILE A CB 1 ATOM 6758 C CG1 . ILE A 1 852 ? -37.222 7.448 21.746 1.00 19.44 ? 852 ILE A CG1 1 ATOM 6759 C CG2 . ILE A 1 852 ? -35.899 9.551 21.335 1.00 18.69 ? 852 ILE A CG2 1 ATOM 6760 C CD1 . ILE A 1 852 ? -37.158 6.773 20.357 1.00 21.53 ? 852 ILE A CD1 1 ATOM 6761 N N . ILE A 1 853 ? -37.095 11.757 23.671 1.00 18.95 ? 853 ILE A N 1 ATOM 6762 C CA . ILE A 1 853 ? -37.068 13.193 23.660 1.00 19.12 ? 853 ILE A CA 1 ATOM 6763 C C . ILE A 1 853 ? -35.911 13.604 22.769 1.00 20.91 ? 853 ILE A C 1 ATOM 6764 O O . ILE A 1 853 ? -34.732 13.303 23.068 1.00 20.51 ? 853 ILE A O 1 ATOM 6765 C CB . ILE A 1 853 ? -36.889 13.779 25.104 1.00 19.15 ? 853 ILE A CB 1 ATOM 6766 C CG1 . ILE A 1 853 ? -37.935 13.191 26.089 1.00 19.60 ? 853 ILE A CG1 1 ATOM 6767 C CG2 . ILE A 1 853 ? -36.863 15.293 25.073 1.00 18.61 ? 853 ILE A CG2 1 ATOM 6768 C CD1 . ILE A 1 853 ? -37.793 13.678 27.569 1.00 19.06 ? 853 ILE A CD1 1 ATOM 6769 N N . THR A 1 854 ? -36.252 14.295 21.681 1.00 22.05 ? 854 THR A N 1 ATOM 6770 C CA . THR A 1 854 ? -35.279 14.855 20.738 1.00 23.61 ? 854 THR A CA 1 ATOM 6771 C C . THR A 1 854 ? -35.483 16.363 20.594 1.00 24.57 ? 854 THR A C 1 ATOM 6772 O O . THR A 1 854 ? -36.289 16.971 21.321 1.00 24.06 ? 854 THR A O 1 ATOM 6773 C CB . THR A 1 854 ? -35.373 14.198 19.334 1.00 23.74 ? 854 THR A CB 1 ATOM 6774 O OG1 . THR A 1 854 ? -36.726 14.237 18.846 1.00 22.58 ? 854 THR A OG1 1 ATOM 6775 C CG2 . THR A 1 854 ? -34.907 12.745 19.371 1.00 23.47 ? 854 THR A CG2 1 ATOM 6776 N N . ASP A 1 855 ? -34.769 16.958 19.637 1.00 24.78 ? 855 ASP A N 1 ATOM 6777 C CA . ASP A 1 855 ? -34.751 18.406 19.449 1.00 25.91 ? 855 ASP A CA 1 ATOM 6778 C C . ASP A 1 855 ? -34.432 19.118 20.784 1.00 26.02 ? 855 ASP A C 1 ATOM 6779 O O . ASP A 1 855 ? -35.137 20.033 21.245 1.00 25.82 ? 855 ASP A O 1 ATOM 6780 C CB . ASP A 1 855 ? -36.063 18.880 18.814 1.00 26.46 ? 855 ASP A CB 1 ATOM 6781 C CG . ASP A 1 855 ? -36.019 20.329 18.422 1.00 29.64 ? 855 ASP A CG 1 ATOM 6782 O OD1 . ASP A 1 855 ? -34.885 20.855 18.210 1.00 31.14 ? 855 ASP A OD1 1 ATOM 6783 O OD2 . ASP A 1 855 ? -37.126 20.937 18.357 1.00 29.81 ? 855 ASP A OD2 1 ATOM 6784 N N . ILE A 1 856 ? -33.355 18.652 21.397 1.00 25.06 ? 856 ILE A N 1 ATOM 6785 C CA . ILE A 1 856 ? -32.958 19.064 22.723 1.00 25.32 ? 856 ILE A CA 1 ATOM 6786 C C . ILE A 1 856 ? -31.437 19.165 22.663 1.00 24.57 ? 856 ILE A C 1 ATOM 6787 O O . ILE A 1 856 ? -30.809 18.556 21.800 1.00 24.04 ? 856 ILE A O 1 ATOM 6788 C CB . ILE A 1 856 ? -33.479 18.065 23.813 1.00 25.06 ? 856 ILE A CB 1 ATOM 6789 C CG1 . ILE A 1 856 ? -33.755 18.793 25.131 1.00 25.35 ? 856 ILE A CG1 1 ATOM 6790 C CG2 . ILE A 1 856 ? -32.551 16.847 23.999 1.00 26.82 ? 856 ILE A CG2 1 ATOM 6791 C CD1 . ILE A 1 856 ? -34.085 17.840 26.312 1.00 26.83 ? 856 ILE A CD1 1 ATOM 6792 N N . ASP A 1 857 ? -30.858 19.969 23.536 1.00 24.40 ? 857 ASP A N 1 ATOM 6793 C CA . ASP A 1 857 ? -29.430 20.242 23.467 1.00 24.07 ? 857 ASP A CA 1 ATOM 6794 C C . ASP A 1 857 ? -28.935 20.478 24.883 1.00 22.64 ? 857 ASP A C 1 ATOM 6795 O O . ASP A 1 857 ? -28.864 21.613 25.333 1.00 23.10 ? 857 ASP A O 1 ATOM 6796 C CB . ASP A 1 857 ? -29.199 21.476 22.572 1.00 25.26 ? 857 ASP A CB 1 ATOM 6797 C CG . ASP A 1 857 ? -27.732 21.741 22.274 1.00 29.01 ? 857 ASP A CG 1 ATOM 6798 O OD1 . ASP A 1 857 ? -27.010 20.810 21.860 1.00 31.68 ? 857 ASP A OD1 1 ATOM 6799 O OD2 . ASP A 1 857 ? -27.320 22.912 22.412 1.00 34.32 ? 857 ASP A OD2 1 ATOM 6800 N N . LEU A 1 858 ? -28.610 19.401 25.601 1.00 21.03 ? 858 LEU A N 1 ATOM 6801 C CA . LEU A 1 858 ? -28.090 19.529 26.958 1.00 19.51 ? 858 LEU A CA 1 ATOM 6802 C C . LEU A 1 858 ? -26.561 19.489 26.931 1.00 20.61 ? 858 LEU A C 1 ATOM 6803 O O . LEU A 1 858 ? -25.962 18.427 26.889 1.00 20.26 ? 858 LEU A O 1 ATOM 6804 C CB . LEU A 1 858 ? -28.628 18.427 27.867 1.00 19.34 ? 858 LEU A CB 1 ATOM 6805 C CG . LEU A 1 858 ? -30.138 18.077 27.840 1.00 19.15 ? 858 LEU A CG 1 ATOM 6806 C CD1 . LEU A 1 858 ? -30.525 17.325 29.096 1.00 21.90 ? 858 LEU A CD1 1 ATOM 6807 C CD2 . LEU A 1 858 ? -30.964 19.319 27.719 1.00 18.51 ? 858 LEU A CD2 1 ATOM 6808 N N . LEU A 1 859 ? -25.939 20.651 26.968 1.00 20.64 ? 859 LEU A N 1 ATOM 6809 C CA . LEU A 1 859 ? -24.490 20.733 26.898 1.00 21.17 ? 859 LEU A CA 1 ATOM 6810 C C . LEU A 1 859 ? -23.801 19.897 27.980 1.00 21.10 ? 859 LEU A C 1 ATOM 6811 O O . LEU A 1 859 ? -24.027 20.058 29.195 1.00 20.37 ? 859 LEU A O 1 ATOM 6812 C CB . LEU A 1 859 ? -24.018 22.196 26.929 1.00 20.41 ? 859 LEU A CB 1 ATOM 6813 C CG . LEU A 1 859 ? -24.553 23.148 25.851 1.00 21.82 ? 859 LEU A CG 1 ATOM 6814 C CD1 . LEU A 1 859 ? -23.990 24.563 26.058 1.00 21.09 ? 859 LEU A CD1 1 ATOM 6815 C CD2 . LEU A 1 859 ? -24.257 22.645 24.433 1.00 20.99 ? 859 LEU A CD2 1 ATOM 6816 N N . LEU A 1 860 ? -22.972 18.975 27.513 1.00 21.93 ? 860 LEU A N 1 ATOM 6817 C CA . LEU A 1 860 ? -22.065 18.247 28.406 1.00 22.82 ? 860 LEU A CA 1 ATOM 6818 C C . LEU A 1 860 ? -21.377 19.270 29.304 1.00 22.84 ? 860 LEU A C 1 ATOM 6819 O O . LEU A 1 860 ? -20.901 20.314 28.818 1.00 23.77 ? 860 LEU A O 1 ATOM 6820 C CB . LEU A 1 860 ? -21.063 17.437 27.579 1.00 22.20 ? 860 LEU A CB 1 ATOM 6821 C CG . LEU A 1 860 ? -20.144 16.455 28.296 1.00 23.41 ? 860 LEU A CG 1 ATOM 6822 C CD1 . LEU A 1 860 ? -20.922 15.276 28.794 1.00 24.34 ? 860 LEU A CD1 1 ATOM 6823 C CD2 . LEU A 1 860 ? -19.014 16.008 27.381 1.00 22.31 ? 860 LEU A CD2 1 ATOM 6824 N N . GLY A 1 861 ? -21.395 19.015 30.606 1.00 22.99 ? 861 GLY A N 1 ATOM 6825 C CA . GLY A 1 861 ? -20.783 19.928 31.573 1.00 24.18 ? 861 GLY A CA 1 ATOM 6826 C C . GLY A 1 861 ? -21.730 20.944 32.198 1.00 24.41 ? 861 GLY A C 1 ATOM 6827 O O . GLY A 1 861 ? -21.326 21.690 33.071 1.00 24.73 ? 861 GLY A O 1 ATOM 6828 N N . GLU A 1 862 ? -22.987 20.988 31.761 1.00 24.45 ? 862 GLU A N 1 ATOM 6829 C CA . GLU A 1 862 ? -23.953 21.935 32.354 1.00 24.32 ? 862 GLU A CA 1 ATOM 6830 C C . GLU A 1 862 ? -25.051 21.224 33.130 1.00 23.33 ? 862 GLU A C 1 ATOM 6831 O O . GLU A 1 862 ? -25.495 20.159 32.744 1.00 23.10 ? 862 GLU A O 1 ATOM 6832 C CB . GLU A 1 862 ? -24.604 22.832 31.277 1.00 24.80 ? 862 GLU A CB 1 ATOM 6833 C CG . GLU A 1 862 ? -23.674 23.790 30.535 1.00 27.08 ? 862 GLU A CG 1 ATOM 6834 C CD . GLU A 1 862 ? -23.017 24.801 31.458 1.00 33.01 ? 862 GLU A CD 1 ATOM 6835 O OE1 . GLU A 1 862 ? -23.738 25.423 32.280 1.00 33.68 ? 862 GLU A OE1 1 ATOM 6836 O OE2 . GLU A 1 862 ? -21.773 24.966 31.368 1.00 35.55 ? 862 GLU A OE2 1 ATOM 6837 N N . ALA A 1 863 ? -25.500 21.843 34.210 1.00 22.71 ? 863 ALA A N 1 ATOM 6838 C CA . ALA A 1 863 ? -26.613 21.338 34.988 1.00 22.85 ? 863 ALA A CA 1 ATOM 6839 C C . ALA A 1 863 ? -27.948 21.694 34.326 1.00 23.15 ? 863 ALA A C 1 ATOM 6840 O O . ALA A 1 863 ? -28.112 22.814 33.834 1.00 23.11 ? 863 ALA A O 1 ATOM 6841 C CB . ALA A 1 863 ? -26.560 21.921 36.364 1.00 23.35 ? 863 ALA A CB 1 ATOM 6842 N N . TYR A 1 864 ? -28.877 20.734 34.313 1.00 22.77 ? 864 TYR A N 1 ATOM 6843 C CA . TYR A 1 864 ? -30.207 20.892 33.706 1.00 22.49 ? 864 TYR A CA 1 ATOM 6844 C C . TYR A 1 864 ? -31.249 20.155 34.539 1.00 22.80 ? 864 TYR A C 1 ATOM 6845 O O . TYR A 1 864 ? -30.929 19.206 35.245 1.00 22.40 ? 864 TYR A O 1 ATOM 6846 C CB . TYR A 1 864 ? -30.274 20.306 32.286 1.00 21.72 ? 864 TYR A CB 1 ATOM 6847 C CG . TYR A 1 864 ? -29.456 21.046 31.263 1.00 22.83 ? 864 TYR A CG 1 ATOM 6848 C CD1 . TYR A 1 864 ? -29.992 22.126 30.552 1.00 21.45 ? 864 TYR A CD1 1 ATOM 6849 C CD2 . TYR A 1 864 ? -28.147 20.662 30.999 1.00 21.94 ? 864 TYR A CD2 1 ATOM 6850 C CE1 . TYR A 1 864 ? -29.221 22.807 29.594 1.00 23.55 ? 864 TYR A CE1 1 ATOM 6851 C CE2 . TYR A 1 864 ? -27.368 21.343 30.076 1.00 22.75 ? 864 TYR A CE2 1 ATOM 6852 C CZ . TYR A 1 864 ? -27.889 22.410 29.378 1.00 22.44 ? 864 TYR A CZ 1 ATOM 6853 O OH . TYR A 1 864 ? -27.089 23.060 28.434 1.00 19.89 ? 864 TYR A OH 1 ATOM 6854 N N . THR A 1 865 ? -32.491 20.609 34.430 1.00 23.51 ? 865 THR A N 1 ATOM 6855 C CA . THR A 1 865 ? -33.649 19.876 34.909 1.00 24.76 ? 865 THR A CA 1 ATOM 6856 C C . THR A 1 865 ? -34.575 19.712 33.705 1.00 25.42 ? 865 THR A C 1 ATOM 6857 O O . THR A 1 865 ? -34.912 20.684 33.041 1.00 26.10 ? 865 THR A O 1 ATOM 6858 C CB . THR A 1 865 ? -34.325 20.612 36.083 1.00 24.62 ? 865 THR A CB 1 ATOM 6859 O OG1 . THR A 1 865 ? -33.388 20.731 37.178 1.00 24.54 ? 865 THR A OG1 1 ATOM 6860 C CG2 . THR A 1 865 ? -35.531 19.836 36.574 1.00 25.55 ? 865 THR A CG2 1 ATOM 6861 N N . VAL A 1 866 ? -34.939 18.479 33.391 1.00 25.85 ? 866 VAL A N 1 ATOM 6862 C CA . VAL A 1 866 ? -35.917 18.219 32.353 1.00 25.94 ? 866 VAL A CA 1 ATOM 6863 C C . VAL A 1 866 ? -37.134 17.757 33.121 1.00 26.90 ? 866 VAL A C 1 ATOM 6864 O O . VAL A 1 866 ? -37.020 16.876 33.964 1.00 27.20 ? 866 VAL A O 1 ATOM 6865 C CB . VAL A 1 866 ? -35.418 17.139 31.361 1.00 25.69 ? 866 VAL A CB 1 ATOM 6866 C CG1 . VAL A 1 866 ? -36.449 16.843 30.274 1.00 24.32 ? 866 VAL A CG1 1 ATOM 6867 C CG2 . VAL A 1 866 ? -34.087 17.569 30.736 1.00 24.19 ? 866 VAL A CG2 1 ATOM 6868 N N . GLU A 1 867 ? -38.281 18.380 32.862 1.00 27.91 ? 867 GLU A N 1 ATOM 6869 C CA . GLU A 1 867 ? -39.487 18.123 33.635 1.00 29.11 ? 867 GLU A CA 1 ATOM 6870 C C . GLU A 1 867 ? -40.633 17.766 32.712 1.00 29.14 ? 867 GLU A C 1 ATOM 6871 O O . GLU A 1 867 ? -40.765 18.328 31.629 1.00 27.90 ? 867 GLU A O 1 ATOM 6872 C CB . GLU A 1 867 ? -39.863 19.347 34.474 1.00 29.59 ? 867 GLU A CB 1 ATOM 6873 C CG . GLU A 1 867 ? -39.080 19.464 35.786 1.00 34.01 ? 867 GLU A CG 1 ATOM 6874 C CD . GLU A 1 867 ? -39.778 20.321 36.831 1.00 38.61 ? 867 GLU A CD 1 ATOM 6875 O OE1 . GLU A 1 867 ? -39.735 21.563 36.703 1.00 40.39 ? 867 GLU A OE1 1 ATOM 6876 O OE2 . GLU A 1 867 ? -40.348 19.744 37.792 1.00 39.91 ? 867 GLU A OE2 1 ATOM 6877 N N . TRP A 1 868 ? -41.481 16.848 33.153 1.00 30.19 ? 868 TRP A N 1 ATOM 6878 C CA . TRP A 1 868 ? -42.653 16.499 32.376 1.00 31.10 ? 868 TRP A CA 1 ATOM 6879 C C . TRP A 1 868 ? -43.840 16.141 33.274 1.00 32.13 ? 868 TRP A C 1 ATOM 6880 O O . TRP A 1 868 ? -43.686 15.942 34.476 1.00 31.62 ? 868 TRP A O 1 ATOM 6881 C CB . TRP A 1 868 ? -42.327 15.368 31.383 1.00 31.05 ? 868 TRP A CB 1 ATOM 6882 C CG . TRP A 1 868 ? -41.957 14.054 32.026 1.00 30.72 ? 868 TRP A CG 1 ATOM 6883 C CD1 . TRP A 1 868 ? -42.813 13.056 32.408 1.00 30.99 ? 868 TRP A CD1 1 ATOM 6884 C CD2 . TRP A 1 868 ? -40.643 13.605 32.370 1.00 30.79 ? 868 TRP A CD2 1 ATOM 6885 N NE1 . TRP A 1 868 ? -42.114 12.019 32.962 1.00 30.64 ? 868 TRP A NE1 1 ATOM 6886 C CE2 . TRP A 1 868 ? -40.778 12.331 32.953 1.00 31.40 ? 868 TRP A CE2 1 ATOM 6887 C CE3 . TRP A 1 868 ? -39.360 14.150 32.226 1.00 29.91 ? 868 TRP A CE3 1 ATOM 6888 C CZ2 . TRP A 1 868 ? -39.674 11.582 33.382 1.00 32.01 ? 868 TRP A CZ2 1 ATOM 6889 C CZ3 . TRP A 1 868 ? -38.265 13.406 32.666 1.00 30.84 ? 868 TRP A CZ3 1 ATOM 6890 C CH2 . TRP A 1 868 ? -38.433 12.145 33.235 1.00 30.81 ? 868 TRP A CH2 1 ATOM 6891 N N . ALA A 1 869 ? -45.018 16.055 32.668 1.00 33.20 ? 869 ALA A N 1 ATOM 6892 C CA . ALA A 1 869 ? -46.218 15.626 33.364 1.00 34.81 ? 869 ALA A CA 1 ATOM 6893 C C . ALA A 1 869 ? -46.740 14.351 32.711 1.00 36.17 ? 869 ALA A C 1 ATOM 6894 O O . ALA A 1 869 ? -46.203 13.900 31.685 1.00 35.77 ? 869 ALA A O 1 ATOM 6895 C CB . ALA A 1 869 ? -47.262 16.720 33.309 1.00 34.99 ? 869 ALA A CB 1 ATOM 6896 N N . HIS A 1 870 ? -47.765 13.757 33.329 1.00 37.90 ? 870 HIS A N 1 ATOM 6897 C CA . HIS A 1 870 ? -48.485 12.625 32.764 1.00 39.00 ? 870 HIS A CA 1 ATOM 6898 C C . HIS A 1 870 ? -49.985 12.928 32.842 1.00 39.78 ? 870 HIS A C 1 ATOM 6899 O O . HIS A 1 870 ? -50.754 12.555 31.952 1.00 40.23 ? 870 HIS A O 1 ATOM 6900 C CB . HIS A 1 870 ? -48.191 11.340 33.537 1.00 39.83 ? 870 HIS A CB 1 ATOM 6901 C CG . HIS A 1 870 ? -46.737 10.976 33.605 1.00 41.43 ? 870 HIS A CG 1 ATOM 6902 N ND1 . HIS A 1 870 ? -46.113 10.213 32.643 1.00 42.48 ? 870 HIS A ND1 1 ATOM 6903 C CD2 . HIS A 1 870 ? -45.794 11.248 34.535 1.00 43.11 ? 870 HIS A CD2 1 ATOM 6904 C CE1 . HIS A 1 870 ? -44.845 10.038 32.971 1.00 43.53 ? 870 HIS A CE1 1 ATOM 6905 N NE2 . HIS A 1 870 ? -44.627 10.652 34.120 1.00 44.63 ? 870 HIS A NE2 1 HETATM 6906 C C1 . NAG B 2 . ? -17.242 9.318 11.268 1.00 35.70 ? 2001 NAG A C1 1 HETATM 6907 C C2 . NAG B 2 . ? -17.779 10.757 11.198 1.00 37.64 ? 2001 NAG A C2 1 HETATM 6908 C C3 . NAG B 2 . ? -17.468 11.367 9.813 1.00 39.41 ? 2001 NAG A C3 1 HETATM 6909 C C4 . NAG B 2 . ? -15.961 11.333 9.581 1.00 37.81 ? 2001 NAG A C4 1 HETATM 6910 C C5 . NAG B 2 . ? -15.503 9.884 9.685 1.00 39.24 ? 2001 NAG A C5 1 HETATM 6911 C C6 . NAG B 2 . ? -13.999 9.732 9.483 1.00 40.82 ? 2001 NAG A C6 1 HETATM 6912 C C7 . NAG B 2 . ? -19.752 11.890 12.142 1.00 40.14 ? 2001 NAG A C7 1 HETATM 6913 C C8 . NAG B 2 . ? -21.188 11.723 12.538 1.00 39.39 ? 2001 NAG A C8 1 HETATM 6914 N N2 . NAG B 2 . ? -19.192 10.828 11.539 1.00 37.74 ? 2001 NAG A N2 1 HETATM 6915 O O3 . NAG B 2 . ? -17.925 12.704 9.681 1.00 39.24 ? 2001 NAG A O3 1 HETATM 6916 O O4 . NAG B 2 . ? -15.650 11.864 8.316 1.00 41.23 ? 2001 NAG A O4 1 HETATM 6917 O O5 . NAG B 2 . ? -15.861 9.347 10.954 1.00 37.93 ? 2001 NAG A O5 1 HETATM 6918 O O6 . NAG B 2 . ? -13.730 8.380 9.158 1.00 43.97 ? 2001 NAG A O6 1 HETATM 6919 O O7 . NAG B 2 . ? -19.181 12.974 12.371 1.00 39.85 ? 2001 NAG A O7 1 HETATM 6920 C C1 . NAG C 2 . ? 24.943 -10.193 35.474 1.00 27.08 ? 2002 NAG A C1 1 HETATM 6921 C C2 . NAG C 2 . ? 24.747 -9.317 36.722 1.00 29.79 ? 2002 NAG A C2 1 HETATM 6922 C C3 . NAG C 2 . ? 25.349 -7.905 36.540 1.00 28.45 ? 2002 NAG A C3 1 HETATM 6923 C C4 . NAG C 2 . ? 26.802 -7.960 36.072 1.00 28.18 ? 2002 NAG A C4 1 HETATM 6924 C C5 . NAG C 2 . ? 26.930 -8.911 34.894 1.00 27.87 ? 2002 NAG A C5 1 HETATM 6925 C C6 . NAG C 2 . ? 28.410 -9.138 34.557 1.00 28.32 ? 2002 NAG A C6 1 HETATM 6926 C C7 . NAG C 2 . ? 22.915 -9.908 38.181 1.00 33.05 ? 2002 NAG A C7 1 HETATM 6927 C C8 . NAG C 2 . ? 21.438 -9.844 38.459 1.00 33.78 ? 2002 NAG A C8 1 HETATM 6928 N N2 . NAG C 2 . ? 23.340 -9.274 37.100 1.00 30.21 ? 2002 NAG A N2 1 HETATM 6929 O O3 . NAG C 2 . ? 25.288 -7.186 37.744 1.00 26.84 ? 2002 NAG A O3 1 HETATM 6930 O O4 . NAG C 2 . ? 27.302 -6.667 35.731 1.00 30.96 ? 2002 NAG A O4 1 HETATM 6931 O O5 . NAG C 2 . ? 26.341 -10.166 35.196 1.00 28.59 ? 2002 NAG A O5 1 HETATM 6932 O O6 . NAG C 2 . ? 28.466 -9.903 33.377 1.00 26.98 ? 2002 NAG A O6 1 HETATM 6933 O O7 . NAG C 2 . ? 23.667 -10.515 38.947 1.00 36.59 ? 2002 NAG A O7 1 HETATM 6934 S S . SO4 D 3 . ? -26.184 -1.448 12.240 1.00 36.07 ? 4001 SO4 A S 1 HETATM 6935 O O1 . SO4 D 3 . ? -24.954 -2.114 11.838 1.00 37.33 ? 4001 SO4 A O1 1 HETATM 6936 O O2 . SO4 D 3 . ? -26.544 -0.556 11.154 1.00 37.43 ? 4001 SO4 A O2 1 HETATM 6937 O O3 . SO4 D 3 . ? -27.256 -2.422 12.435 1.00 39.05 ? 4001 SO4 A O3 1 HETATM 6938 O O4 . SO4 D 3 . ? -26.032 -0.664 13.452 1.00 36.46 ? 4001 SO4 A O4 1 HETATM 6939 O O7 . 3CU E 4 . ? 1.203 -15.881 23.461 1.00 16.35 ? 1001 3CU A O7 1 HETATM 6940 C C7 . 3CU E 4 . ? 0.837 -16.391 22.191 1.00 17.72 ? 1001 3CU A C7 1 HETATM 6941 C C7A . 3CU E 4 . ? 0.985 -15.255 21.171 1.00 18.01 ? 1001 3CU A C7A 1 HETATM 6942 C C1 . 3CU E 4 . ? -0.113 -15.292 20.086 1.00 19.02 ? 1001 3CU A C1 1 HETATM 6943 O O1 . 3CU E 4 . ? -1.248 -14.457 20.375 1.00 16.00 ? 1001 3CU A O1 1 HETATM 6944 C C2 . 3CU E 4 . ? 0.705 -14.742 18.914 1.00 18.00 ? 1001 3CU A C2 1 HETATM 6945 O O2 . 3CU E 4 . ? 0.042 -14.937 17.680 1.00 18.32 ? 1001 3CU A O2 1 HETATM 6946 C C3 . 3CU E 4 . ? 1.867 -15.700 18.998 1.00 16.43 ? 1001 3CU A C3 1 HETATM 6947 C C8 . 3CU E 4 . ? 3.053 -15.275 18.113 1.00 15.10 ? 1001 3CU A C8 1 HETATM 6948 O O8 . 3CU E 4 . ? 3.387 -13.911 18.365 1.00 17.54 ? 1001 3CU A O8 1 HETATM 6949 N N4 . 3CU E 4 . ? 2.248 -15.556 20.421 1.00 19.73 ? 1001 3CU A N4 1 HETATM 6950 C C5 . 3CU E 4 . ? 2.858 -16.806 20.959 1.00 17.70 ? 1001 3CU A C5 1 HETATM 6951 C C6 . 3CU E 4 . ? 1.795 -17.516 21.744 1.00 19.38 ? 1001 3CU A C6 1 HETATM 6952 O OXT . 3CU E 4 . ? 1.083 -18.391 20.865 1.00 19.77 ? 1001 3CU A OXT 1 HETATM 6953 C C1 . GOL F 5 . ? 2.694 -21.038 22.517 1.00 24.98 ? 3001 GOL A C1 1 HETATM 6954 O O1 . GOL F 5 . ? 2.547 -20.288 23.709 1.00 27.24 ? 3001 GOL A O1 1 HETATM 6955 C C2 . GOL F 5 . ? 4.118 -20.803 21.995 1.00 28.23 ? 3001 GOL A C2 1 HETATM 6956 O O2 . GOL F 5 . ? 5.022 -20.908 23.062 1.00 28.33 ? 3001 GOL A O2 1 HETATM 6957 C C3 . GOL F 5 . ? 4.463 -21.896 20.990 1.00 29.01 ? 3001 GOL A C3 1 HETATM 6958 O O3 . GOL F 5 . ? 3.749 -21.585 19.820 1.00 30.53 ? 3001 GOL A O3 1 HETATM 6959 C C1 . GOL G 5 . ? -4.787 -1.157 31.071 1.00 32.30 ? 3002 GOL A C1 1 HETATM 6960 O O1 . GOL G 5 . ? -6.170 -1.005 31.349 1.00 36.49 ? 3002 GOL A O1 1 HETATM 6961 C C2 . GOL G 5 . ? -4.499 -0.879 29.598 1.00 31.51 ? 3002 GOL A C2 1 HETATM 6962 O O2 . GOL G 5 . ? -4.877 0.432 29.282 1.00 31.99 ? 3002 GOL A O2 1 HETATM 6963 C C3 . GOL G 5 . ? -2.991 -0.967 29.371 1.00 31.02 ? 3002 GOL A C3 1 HETATM 6964 O O3 . GOL G 5 . ? -2.372 0.296 29.378 1.00 26.94 ? 3002 GOL A O3 1 HETATM 6965 C C1 . GOL H 5 . ? -6.385 -11.934 2.423 1.00 32.43 ? 3003 GOL A C1 1 HETATM 6966 O O1 . GOL H 5 . ? -7.615 -12.614 2.227 1.00 34.48 ? 3003 GOL A O1 1 HETATM 6967 C C2 . GOL H 5 . ? -5.756 -12.493 3.679 1.00 31.30 ? 3003 GOL A C2 1 HETATM 6968 O O2 . GOL H 5 . ? -5.958 -13.883 3.665 1.00 32.11 ? 3003 GOL A O2 1 HETATM 6969 C C3 . GOL H 5 . ? -4.257 -12.226 3.702 1.00 31.08 ? 3003 GOL A C3 1 HETATM 6970 O O3 . GOL H 5 . ? -3.782 -12.502 5.006 1.00 32.99 ? 3003 GOL A O3 1 HETATM 6971 C C1 . GOL I 5 . ? -4.310 -11.382 70.224 1.00 36.68 ? 3004 GOL A C1 1 HETATM 6972 O O1 . GOL I 5 . ? -4.160 -10.152 70.870 1.00 33.52 ? 3004 GOL A O1 1 HETATM 6973 C C2 . GOL I 5 . ? -5.649 -11.930 70.677 1.00 38.69 ? 3004 GOL A C2 1 HETATM 6974 O O2 . GOL I 5 . ? -6.661 -11.114 70.120 1.00 40.22 ? 3004 GOL A O2 1 HETATM 6975 C C3 . GOL I 5 . ? -5.759 -13.355 70.186 1.00 36.50 ? 3004 GOL A C3 1 HETATM 6976 O O3 . GOL I 5 . ? -6.548 -14.164 71.034 1.00 36.95 ? 3004 GOL A O3 1 HETATM 6977 C C1 . GOL J 5 . ? -15.163 -22.348 60.388 1.00 36.67 ? 3005 GOL A C1 1 HETATM 6978 O O1 . GOL J 5 . ? -16.021 -21.924 59.348 1.00 27.63 ? 3005 GOL A O1 1 HETATM 6979 C C2 . GOL J 5 . ? -15.818 -22.282 61.757 1.00 38.21 ? 3005 GOL A C2 1 HETATM 6980 O O2 . GOL J 5 . ? -17.005 -23.040 61.726 1.00 42.09 ? 3005 GOL A O2 1 HETATM 6981 C C3 . GOL J 5 . ? -14.897 -22.846 62.838 1.00 40.68 ? 3005 GOL A C3 1 HETATM 6982 O O3 . GOL J 5 . ? -13.901 -21.907 63.195 1.00 42.92 ? 3005 GOL A O3 1 HETATM 6983 C C1 . GOL K 5 . ? -5.150 3.758 1.871 1.00 67.72 ? 3006 GOL A C1 1 HETATM 6984 O O1 . GOL K 5 . ? -4.829 5.067 2.306 1.00 66.46 ? 3006 GOL A O1 1 HETATM 6985 C C2 . GOL K 5 . ? -4.427 2.772 2.787 1.00 68.05 ? 3006 GOL A C2 1 HETATM 6986 O O2 . GOL K 5 . ? -4.806 3.016 4.128 1.00 68.93 ? 3006 GOL A O2 1 HETATM 6987 C C3 . GOL K 5 . ? -4.684 1.312 2.417 1.00 67.88 ? 3006 GOL A C3 1 HETATM 6988 O O3 . GOL K 5 . ? -4.464 0.493 3.549 1.00 66.87 ? 3006 GOL A O3 1 HETATM 6989 C C1 . GOL L 5 . ? -4.398 16.004 32.352 1.00 44.09 ? 3007 GOL A C1 1 HETATM 6990 O O1 . GOL L 5 . ? -4.165 16.415 33.677 1.00 41.26 ? 3007 GOL A O1 1 HETATM 6991 C C2 . GOL L 5 . ? -5.129 17.096 31.573 1.00 44.54 ? 3007 GOL A C2 1 HETATM 6992 O O2 . GOL L 5 . ? -4.203 18.114 31.292 1.00 46.95 ? 3007 GOL A O2 1 HETATM 6993 C C3 . GOL L 5 . ? -5.704 16.528 30.274 1.00 44.68 ? 3007 GOL A C3 1 HETATM 6994 O O3 . GOL L 5 . ? -6.964 17.054 29.904 1.00 42.35 ? 3007 GOL A O3 1 HETATM 6995 C C1 . GOL M 5 . ? -25.016 5.327 14.322 1.00 43.17 ? 3008 GOL A C1 1 HETATM 6996 O O1 . GOL M 5 . ? -26.222 6.035 14.573 1.00 40.44 ? 3008 GOL A O1 1 HETATM 6997 C C2 . GOL M 5 . ? -24.104 5.985 13.283 1.00 42.02 ? 3008 GOL A C2 1 HETATM 6998 O O2 . GOL M 5 . ? -23.478 7.119 13.810 1.00 39.93 ? 3008 GOL A O2 1 HETATM 6999 C C3 . GOL M 5 . ? -22.990 5.041 12.855 1.00 43.35 ? 3008 GOL A C3 1 HETATM 7000 O O3 . GOL M 5 . ? -22.515 5.425 11.581 1.00 42.53 ? 3008 GOL A O3 1 HETATM 7001 C C1 . GOL N 5 . ? -11.105 -15.470 71.920 1.00 42.77 ? 3009 GOL A C1 1 HETATM 7002 O O1 . GOL N 5 . ? -10.863 -15.595 73.317 1.00 40.69 ? 3009 GOL A O1 1 HETATM 7003 C C2 . GOL N 5 . ? -10.982 -14.041 71.363 1.00 42.19 ? 3009 GOL A C2 1 HETATM 7004 O O2 . GOL N 5 . ? -11.593 -13.048 72.154 1.00 43.90 ? 3009 GOL A O2 1 HETATM 7005 C C3 . GOL N 5 . ? -9.542 -13.655 71.037 1.00 42.21 ? 3009 GOL A C3 1 HETATM 7006 O O3 . GOL N 5 . ? -9.490 -12.359 70.461 1.00 42.53 ? 3009 GOL A O3 1 HETATM 7007 O O . HOH O 6 . ? 2.745 -42.833 50.533 1.00 18.13 ? 4002 HOH A O 1 HETATM 7008 O O . HOH O 6 . ? 10.625 -15.911 34.618 1.00 18.60 ? 4003 HOH A O 1 HETATM 7009 O O . HOH O 6 . ? -1.546 -13.864 33.217 1.00 21.00 ? 4004 HOH A O 1 HETATM 7010 O O . HOH O 6 . ? -7.970 -14.161 10.746 1.00 18.76 ? 4005 HOH A O 1 HETATM 7011 O O . HOH O 6 . ? 11.541 -28.784 39.301 1.00 17.61 ? 4006 HOH A O 1 HETATM 7012 O O . HOH O 6 . ? -8.004 -2.813 51.817 1.00 18.96 ? 4007 HOH A O 1 HETATM 7013 O O . HOH O 6 . ? -3.725 -6.205 39.070 1.00 10.35 ? 4008 HOH A O 1 HETATM 7014 O O . HOH O 6 . ? 9.345 -21.507 43.448 1.00 17.93 ? 4009 HOH A O 1 HETATM 7015 O O . HOH O 6 . ? -9.054 15.432 30.628 1.00 18.39 ? 4010 HOH A O 1 HETATM 7016 O O . HOH O 6 . ? -31.824 -11.757 41.317 1.00 20.23 ? 4011 HOH A O 1 HETATM 7017 O O . HOH O 6 . ? -19.995 -6.711 59.285 1.00 23.19 ? 4012 HOH A O 1 HETATM 7018 O O . HOH O 6 . ? -4.011 -32.478 49.098 1.00 23.43 ? 4013 HOH A O 1 HETATM 7019 O O . HOH O 6 . ? -4.423 -9.086 41.117 1.00 11.15 ? 4014 HOH A O 1 HETATM 7020 O O . HOH O 6 . ? -17.693 7.300 21.710 1.00 17.43 ? 4015 HOH A O 1 HETATM 7021 O O . HOH O 6 . ? -22.216 -13.954 35.987 1.00 14.54 ? 4016 HOH A O 1 HETATM 7022 O O . HOH O 6 . ? -8.147 -12.592 13.027 1.00 13.66 ? 4017 HOH A O 1 HETATM 7023 O O . HOH O 6 . ? 6.127 -14.158 34.967 1.00 13.67 ? 4018 HOH A O 1 HETATM 7024 O O . HOH O 6 . ? -18.198 -6.519 61.363 1.00 17.11 ? 4019 HOH A O 1 HETATM 7025 O O . HOH O 6 . ? -4.743 9.176 37.585 1.00 26.20 ? 4020 HOH A O 1 HETATM 7026 O O . HOH O 6 . ? -7.863 -17.741 36.466 1.00 15.13 ? 4021 HOH A O 1 HETATM 7027 O O . HOH O 6 . ? -21.310 -6.246 45.071 1.00 16.39 ? 4022 HOH A O 1 HETATM 7028 O O . HOH O 6 . ? -20.286 -20.956 38.290 1.00 15.44 ? 4023 HOH A O 1 HETATM 7029 O O . HOH O 6 . ? 2.385 -8.262 34.107 1.00 20.16 ? 4024 HOH A O 1 HETATM 7030 O O . HOH O 6 . ? -3.333 4.054 31.466 1.00 16.84 ? 4025 HOH A O 1 HETATM 7031 O O . HOH O 6 . ? -6.789 -32.819 49.297 1.00 25.67 ? 4026 HOH A O 1 HETATM 7032 O O . HOH O 6 . ? -3.254 7.279 25.132 1.00 20.70 ? 4027 HOH A O 1 HETATM 7033 O O . HOH O 6 . ? -13.434 -18.541 40.108 1.00 16.99 ? 4028 HOH A O 1 HETATM 7034 O O . HOH O 6 . ? -2.388 -27.138 56.668 1.00 16.75 ? 4029 HOH A O 1 HETATM 7035 O O . HOH O 6 . ? 6.132 -12.062 50.345 1.00 16.75 ? 4030 HOH A O 1 HETATM 7036 O O . HOH O 6 . ? -19.928 6.047 20.512 1.00 13.34 ? 4031 HOH A O 1 HETATM 7037 O O . HOH O 6 . ? -20.489 -16.300 5.704 1.00 22.66 ? 4032 HOH A O 1 HETATM 7038 O O . HOH O 6 . ? -18.899 -19.192 61.845 1.00 22.51 ? 4033 HOH A O 1 HETATM 7039 O O . HOH O 6 . ? -7.420 -12.316 8.617 1.00 13.64 ? 4034 HOH A O 1 HETATM 7040 O O . HOH O 6 . ? -7.903 -16.434 24.458 1.00 15.77 ? 4035 HOH A O 1 HETATM 7041 O O . HOH O 6 . ? -22.257 -26.689 21.952 1.00 22.72 ? 4036 HOH A O 1 HETATM 7042 O O . HOH O 6 . ? -2.431 -30.710 52.848 1.00 15.99 ? 4037 HOH A O 1 HETATM 7043 O O . HOH O 6 . ? -6.189 -33.383 59.227 1.00 11.73 ? 4038 HOH A O 1 HETATM 7044 O O . HOH O 6 . ? 6.676 -21.031 30.475 1.00 13.51 ? 4039 HOH A O 1 HETATM 7045 O O . HOH O 6 . ? -31.651 -9.980 43.918 1.00 22.74 ? 4040 HOH A O 1 HETATM 7046 O O . HOH O 6 . ? 0.770 5.448 1.857 1.00 25.01 ? 4041 HOH A O 1 HETATM 7047 O O . HOH O 6 . ? -21.632 -13.631 57.078 1.00 24.31 ? 4042 HOH A O 1 HETATM 7048 O O . HOH O 6 . ? 12.278 -18.762 49.206 1.00 19.88 ? 4043 HOH A O 1 HETATM 7049 O O . HOH O 6 . ? -42.626 -2.331 27.566 1.00 23.33 ? 4044 HOH A O 1 HETATM 7050 O O . HOH O 6 . ? -6.896 -10.381 10.946 1.00 15.80 ? 4045 HOH A O 1 HETATM 7051 O O . HOH O 6 . ? -24.525 5.220 34.579 1.00 16.41 ? 4046 HOH A O 1 HETATM 7052 O O . HOH O 6 . ? -0.708 -13.262 43.056 1.00 19.34 ? 4047 HOH A O 1 HETATM 7053 O O . HOH O 6 . ? -29.517 -10.241 28.481 1.00 19.53 ? 4048 HOH A O 1 HETATM 7054 O O . HOH O 6 . ? -12.254 -25.801 41.945 1.00 16.95 ? 4049 HOH A O 1 HETATM 7055 O O . HOH O 6 . ? -13.618 0.549 9.878 1.00 15.81 ? 4050 HOH A O 1 HETATM 7056 O O . HOH O 6 . ? -7.389 -11.449 22.247 1.00 15.61 ? 4051 HOH A O 1 HETATM 7057 O O . HOH O 6 . ? -2.899 -6.020 75.937 1.00 20.19 ? 4052 HOH A O 1 HETATM 7058 O O . HOH O 6 . ? -6.640 -31.797 52.119 1.00 13.58 ? 4053 HOH A O 1 HETATM 7059 O O . HOH O 6 . ? -10.961 -18.711 30.112 1.00 21.51 ? 4054 HOH A O 1 HETATM 7060 O O . HOH O 6 . ? -4.737 -3.891 39.345 1.00 20.41 ? 4055 HOH A O 1 HETATM 7061 O O . HOH O 6 . ? -5.561 -13.267 6.968 1.00 21.25 ? 4056 HOH A O 1 HETATM 7062 O O . HOH O 6 . ? 15.831 -10.554 19.038 1.00 18.97 ? 4057 HOH A O 1 HETATM 7063 O O . HOH O 6 . ? -14.563 14.515 22.022 1.00 11.91 ? 4058 HOH A O 1 HETATM 7064 O O . HOH O 6 . ? -9.559 -26.494 32.647 1.00 17.03 ? 4059 HOH A O 1 HETATM 7065 O O . HOH O 6 . ? -23.255 -15.400 21.295 1.00 14.44 ? 4060 HOH A O 1 HETATM 7066 O O . HOH O 6 . ? 2.661 -5.950 64.553 1.00 16.94 ? 4061 HOH A O 1 HETATM 7067 O O . HOH O 6 . ? -3.579 -24.598 58.784 1.00 17.29 ? 4062 HOH A O 1 HETATM 7068 O O . HOH O 6 . ? -0.018 -2.696 41.331 1.00 21.26 ? 4063 HOH A O 1 HETATM 7069 O O . HOH O 6 . ? -25.279 18.265 31.010 1.00 18.20 ? 4064 HOH A O 1 HETATM 7070 O O . HOH O 6 . ? -40.647 0.158 27.975 1.00 21.18 ? 4065 HOH A O 1 HETATM 7071 O O . HOH O 6 . ? -24.584 -19.753 33.998 1.00 20.22 ? 4066 HOH A O 1 HETATM 7072 O O . HOH O 6 . ? 6.324 -12.126 60.981 1.00 13.67 ? 4067 HOH A O 1 HETATM 7073 O O . HOH O 6 . ? -29.955 -7.655 20.650 1.00 30.21 ? 4068 HOH A O 1 HETATM 7074 O O . HOH O 6 . ? -25.015 -4.280 10.179 1.00 26.37 ? 4069 HOH A O 1 HETATM 7075 O O . HOH O 6 . ? -9.958 0.412 45.729 1.00 23.74 ? 4070 HOH A O 1 HETATM 7076 O O . HOH O 6 . ? -25.673 -17.603 28.002 1.00 19.49 ? 4071 HOH A O 1 HETATM 7077 O O . HOH O 6 . ? -4.139 -12.385 43.051 1.00 13.15 ? 4072 HOH A O 1 HETATM 7078 O O . HOH O 6 . ? -7.889 -18.370 26.508 1.00 21.72 ? 4073 HOH A O 1 HETATM 7079 O O . HOH O 6 . ? -6.165 -24.176 33.358 1.00 21.32 ? 4074 HOH A O 1 HETATM 7080 O O . HOH O 6 . ? 14.600 -19.746 56.911 1.00 23.95 ? 4075 HOH A O 1 HETATM 7081 O O . HOH O 6 . ? 19.368 -15.579 17.800 1.00 24.51 ? 4076 HOH A O 1 HETATM 7082 O O . HOH O 6 . ? -23.857 -8.931 60.339 1.00 29.55 ? 4077 HOH A O 1 HETATM 7083 O O . HOH O 6 . ? 13.346 -10.571 19.785 1.00 20.75 ? 4078 HOH A O 1 HETATM 7084 O O . HOH O 6 . ? -32.503 -3.424 40.683 1.00 25.92 ? 4079 HOH A O 1 HETATM 7085 O O . HOH O 6 . ? -0.576 6.241 22.295 1.00 22.55 ? 4080 HOH A O 1 HETATM 7086 O O . HOH O 6 . ? -11.157 3.716 9.812 1.00 18.24 ? 4081 HOH A O 1 HETATM 7087 O O . HOH O 6 . ? 0.187 -20.121 36.818 1.00 18.43 ? 4082 HOH A O 1 HETATM 7088 O O . HOH O 6 . ? 4.649 -32.274 40.175 1.00 25.15 ? 4083 HOH A O 1 HETATM 7089 O O . HOH O 6 . ? -17.189 -16.988 66.227 1.00 31.97 ? 4084 HOH A O 1 HETATM 7090 O O . HOH O 6 . ? 10.084 -28.003 47.652 1.00 20.07 ? 4085 HOH A O 1 HETATM 7091 O O . HOH O 6 . ? -24.270 3.503 36.576 1.00 35.50 ? 4086 HOH A O 1 HETATM 7092 O O . HOH O 6 . ? -7.384 -35.291 48.959 1.00 26.68 ? 4087 HOH A O 1 HETATM 7093 O O . HOH O 6 . ? -11.472 -3.406 23.530 1.00 19.52 ? 4088 HOH A O 1 HETATM 7094 O O . HOH O 6 . ? -17.186 -13.052 42.486 1.00 23.05 ? 4089 HOH A O 1 HETATM 7095 O O . HOH O 6 . ? -11.759 -18.837 25.066 1.00 13.67 ? 4090 HOH A O 1 HETATM 7096 O O . HOH O 6 . ? 6.834 -12.778 6.145 1.00 27.53 ? 4091 HOH A O 1 HETATM 7097 O O . HOH O 6 . ? -39.307 20.665 19.086 1.00 27.97 ? 4092 HOH A O 1 HETATM 7098 O O . HOH O 6 . ? 0.489 -31.428 53.160 1.00 18.45 ? 4093 HOH A O 1 HETATM 7099 O O . HOH O 6 . ? 12.662 -27.467 52.554 1.00 18.67 ? 4094 HOH A O 1 HETATM 7100 O O . HOH O 6 . ? 6.169 -10.394 51.865 1.00 20.71 ? 4095 HOH A O 1 HETATM 7101 O O . HOH O 6 . ? -11.001 -19.585 34.463 1.00 19.35 ? 4096 HOH A O 1 HETATM 7102 O O . HOH O 6 . ? -14.914 -25.411 57.249 1.00 25.44 ? 4097 HOH A O 1 HETATM 7103 O O . HOH O 6 . ? -6.350 -17.959 30.376 1.00 23.22 ? 4098 HOH A O 1 HETATM 7104 O O . HOH O 6 . ? 16.344 -14.478 13.699 1.00 25.44 ? 4099 HOH A O 1 HETATM 7105 O O . HOH O 6 . ? -21.845 -5.012 58.503 1.00 31.25 ? 4100 HOH A O 1 HETATM 7106 O O . HOH O 6 . ? -14.853 6.938 12.021 1.00 32.73 ? 4101 HOH A O 1 HETATM 7107 O O . HOH O 6 . ? -3.975 -39.318 51.802 1.00 20.31 ? 4102 HOH A O 1 HETATM 7108 O O . HOH O 6 . ? -14.800 2.083 7.921 1.00 24.16 ? 4103 HOH A O 1 HETATM 7109 O O . HOH O 6 . ? -23.238 17.023 31.584 1.00 27.16 ? 4104 HOH A O 1 HETATM 7110 O O . HOH O 6 . ? -3.083 -31.786 46.439 1.00 25.76 ? 4105 HOH A O 1 HETATM 7111 O O . HOH O 6 . ? -26.342 -21.273 25.005 1.00 28.03 ? 4106 HOH A O 1 HETATM 7112 O O . HOH O 6 . ? 7.713 -14.562 50.085 1.00 17.11 ? 4107 HOH A O 1 HETATM 7113 O O . HOH O 6 . ? -2.730 7.414 22.516 1.00 34.34 ? 4108 HOH A O 1 HETATM 7114 O O . HOH O 6 . ? -12.571 -6.339 67.218 1.00 35.77 ? 4109 HOH A O 1 HETATM 7115 O O . HOH O 6 . ? -20.659 1.022 11.012 1.00 24.66 ? 4110 HOH A O 1 HETATM 7116 O O . HOH O 6 . ? -35.198 -2.696 38.449 1.00 20.06 ? 4111 HOH A O 1 HETATM 7117 O O . HOH O 6 . ? -9.905 7.719 20.826 1.00 29.56 ? 4112 HOH A O 1 HETATM 7118 O O . HOH O 6 . ? -18.118 19.668 25.114 1.00 27.04 ? 4113 HOH A O 1 HETATM 7119 O O . HOH O 6 . ? -44.617 6.578 33.936 1.00 28.58 ? 4114 HOH A O 1 HETATM 7120 O O . HOH O 6 . ? 3.229 7.918 29.207 1.00 22.70 ? 4115 HOH A O 1 HETATM 7121 O O . HOH O 6 . ? -14.023 10.795 27.606 1.00 21.33 ? 4116 HOH A O 1 HETATM 7122 O O . HOH O 6 . ? -4.998 1.731 27.400 1.00 15.38 ? 4117 HOH A O 1 HETATM 7123 O O . HOH O 6 . ? -23.202 -14.757 38.936 1.00 23.84 ? 4118 HOH A O 1 HETATM 7124 O O . HOH O 6 . ? 19.847 -13.918 29.751 1.00 20.41 ? 4119 HOH A O 1 HETATM 7125 O O . HOH O 6 . ? 7.423 -21.492 33.256 1.00 24.91 ? 4120 HOH A O 1 HETATM 7126 O O . HOH O 6 . ? -38.508 12.332 19.499 1.00 21.32 ? 4121 HOH A O 1 HETATM 7127 O O . HOH O 6 . ? 2.926 -32.166 37.949 1.00 33.50 ? 4122 HOH A O 1 HETATM 7128 O O . HOH O 6 . ? 26.144 -15.818 27.379 1.00 38.79 ? 4123 HOH A O 1 HETATM 7129 O O . HOH O 6 . ? -4.415 5.447 34.919 1.00 30.87 ? 4124 HOH A O 1 HETATM 7130 O O . HOH O 6 . ? -11.203 22.083 29.455 1.00 28.84 ? 4125 HOH A O 1 HETATM 7131 O O . HOH O 6 . ? -11.500 12.388 19.379 1.00 20.13 ? 4126 HOH A O 1 HETATM 7132 O O . HOH O 6 . ? -16.035 -8.314 2.744 1.00 31.15 ? 4127 HOH A O 1 HETATM 7133 O O . HOH O 6 . ? 4.792 -25.913 34.457 1.00 22.16 ? 4128 HOH A O 1 HETATM 7134 O O . HOH O 6 . ? -33.802 -10.787 45.092 1.00 26.18 ? 4129 HOH A O 1 HETATM 7135 O O . HOH O 6 . ? 16.007 -14.903 45.736 1.00 29.43 ? 4130 HOH A O 1 HETATM 7136 O O . HOH O 6 . ? -12.359 1.942 11.427 1.00 26.33 ? 4131 HOH A O 1 HETATM 7137 O O . HOH O 6 . ? 10.584 -13.834 23.866 1.00 20.54 ? 4132 HOH A O 1 HETATM 7138 O O . HOH O 6 . ? -5.106 -29.836 52.092 1.00 22.88 ? 4133 HOH A O 1 HETATM 7139 O O . HOH O 6 . ? -12.283 13.437 21.607 1.00 20.43 ? 4134 HOH A O 1 HETATM 7140 O O . HOH O 6 . ? -4.448 -23.328 21.298 1.00 30.09 ? 4135 HOH A O 1 HETATM 7141 O O . HOH O 6 . ? -4.349 2.233 43.363 1.00 26.19 ? 4136 HOH A O 1 HETATM 7142 O O . HOH O 6 . ? 11.760 -11.911 8.248 1.00 25.44 ? 4137 HOH A O 1 HETATM 7143 O O . HOH O 6 . ? -8.768 -18.373 31.631 1.00 24.41 ? 4138 HOH A O 1 HETATM 7144 O O . HOH O 6 . ? -9.933 -21.913 26.491 1.00 28.10 ? 4139 HOH A O 1 HETATM 7145 O O . HOH O 6 . ? -32.984 13.690 41.646 1.00 33.37 ? 4140 HOH A O 1 HETATM 7146 O O . HOH O 6 . ? 5.775 5.098 11.281 1.00 37.30 ? 4141 HOH A O 1 HETATM 7147 O O . HOH O 6 . ? 1.403 -4.361 54.113 1.00 24.61 ? 4142 HOH A O 1 HETATM 7148 O O . HOH O 6 . ? -10.422 -38.393 64.385 1.00 35.72 ? 4143 HOH A O 1 HETATM 7149 O O . HOH O 6 . ? 7.357 -15.656 47.735 1.00 20.85 ? 4144 HOH A O 1 HETATM 7150 O O . HOH O 6 . ? -2.237 5.201 0.892 1.00 22.80 ? 4145 HOH A O 1 HETATM 7151 O O . HOH O 6 . ? 8.366 -22.288 25.800 1.00 30.44 ? 4146 HOH A O 1 HETATM 7152 O O . HOH O 6 . ? -7.854 -27.648 51.937 1.00 14.14 ? 4147 HOH A O 1 HETATM 7153 O O . HOH O 6 . ? -22.885 -21.874 9.656 1.00 28.02 ? 4148 HOH A O 1 HETATM 7154 O O . HOH O 6 . ? -16.921 -0.136 37.195 1.00 13.28 ? 4149 HOH A O 1 HETATM 7155 O O . HOH O 6 . ? 4.046 -4.557 62.784 1.00 33.52 ? 4150 HOH A O 1 HETATM 7156 O O . HOH O 6 . ? 9.541 -11.877 11.414 1.00 22.16 ? 4151 HOH A O 1 HETATM 7157 O O . HOH O 6 . ? 14.648 -2.799 10.738 1.00 27.28 ? 4152 HOH A O 1 HETATM 7158 O O . HOH O 6 . ? -11.600 -10.259 23.008 1.00 13.46 ? 4153 HOH A O 1 HETATM 7159 O O . HOH O 6 . ? 16.293 -32.313 36.463 1.00 22.31 ? 4154 HOH A O 1 HETATM 7160 O O . HOH O 6 . ? -41.404 -5.645 21.714 1.00 36.28 ? 4155 HOH A O 1 HETATM 7161 O O . HOH O 6 . ? -13.682 -17.041 6.262 1.00 28.37 ? 4156 HOH A O 1 HETATM 7162 O O . HOH O 6 . ? 11.287 -12.233 19.113 1.00 24.41 ? 4157 HOH A O 1 HETATM 7163 O O . HOH O 6 . ? -18.849 0.572 38.652 1.00 20.64 ? 4158 HOH A O 1 HETATM 7164 O O . HOH O 6 . ? -6.906 -32.472 45.089 1.00 17.94 ? 4159 HOH A O 1 HETATM 7165 O O . HOH O 6 . ? -25.603 -14.771 21.222 1.00 19.86 ? 4160 HOH A O 1 HETATM 7166 O O . HOH O 6 . ? -19.784 -19.716 30.179 1.00 22.29 ? 4161 HOH A O 1 HETATM 7167 O O . HOH O 6 . ? 25.192 -18.615 30.453 1.00 22.78 ? 4162 HOH A O 1 HETATM 7168 O O . HOH O 6 . ? 4.166 7.745 35.676 1.00 39.16 ? 4163 HOH A O 1 HETATM 7169 O O . HOH O 6 . ? -12.687 21.342 41.327 1.00 34.23 ? 4164 HOH A O 1 HETATM 7170 O O . HOH O 6 . ? 10.211 0.718 4.283 1.00 33.89 ? 4165 HOH A O 1 HETATM 7171 O O . HOH O 6 . ? -17.691 -5.559 56.170 1.00 23.10 ? 4166 HOH A O 1 HETATM 7172 O O . HOH O 6 . ? -36.025 -9.589 25.214 1.00 27.46 ? 4167 HOH A O 1 HETATM 7173 O O . HOH O 6 . ? -22.364 5.462 33.327 1.00 21.82 ? 4168 HOH A O 1 HETATM 7174 O O . HOH O 6 . ? -18.082 -21.190 63.150 1.00 42.15 ? 4169 HOH A O 1 HETATM 7175 O O . HOH O 6 . ? -24.631 -15.458 5.515 1.00 27.85 ? 4170 HOH A O 1 HETATM 7176 O O . HOH O 6 . ? -12.068 0.322 49.819 1.00 30.49 ? 4171 HOH A O 1 HETATM 7177 O O . HOH O 6 . ? 11.902 -14.716 57.633 1.00 28.72 ? 4172 HOH A O 1 HETATM 7178 O O . HOH O 6 . ? 7.349 -24.629 34.280 1.00 30.14 ? 4173 HOH A O 1 HETATM 7179 O O . HOH O 6 . ? -31.429 2.401 22.363 1.00 44.07 ? 4174 HOH A O 1 HETATM 7180 O O . HOH O 6 . ? -28.091 -17.269 52.409 1.00 29.27 ? 4175 HOH A O 1 HETATM 7181 O O . HOH O 6 . ? -8.385 -31.423 47.540 1.00 28.05 ? 4176 HOH A O 1 HETATM 7182 O O . HOH O 6 . ? -39.179 3.917 20.547 1.00 33.97 ? 4177 HOH A O 1 HETATM 7183 O O . HOH O 6 . ? -5.648 -25.612 31.060 1.00 19.60 ? 4178 HOH A O 1 HETATM 7184 O O . HOH O 6 . ? -7.371 11.038 11.681 1.00 38.49 ? 4179 HOH A O 1 HETATM 7185 O O . HOH O 6 . ? 12.388 -9.451 34.876 1.00 20.47 ? 4180 HOH A O 1 HETATM 7186 O O . HOH O 6 . ? -21.774 -0.174 40.669 1.00 27.46 ? 4181 HOH A O 1 HETATM 7187 O O . HOH O 6 . ? -12.803 -20.736 32.694 1.00 22.46 ? 4182 HOH A O 1 HETATM 7188 O O . HOH O 6 . ? 0.426 1.495 31.653 1.00 22.48 ? 4183 HOH A O 1 HETATM 7189 O O . HOH O 6 . ? 22.188 -8.149 34.696 1.00 21.31 ? 4184 HOH A O 1 HETATM 7190 O O . HOH O 6 . ? -22.333 -22.575 51.131 1.00 39.53 ? 4185 HOH A O 1 HETATM 7191 O O . HOH O 6 . ? 9.848 -4.780 18.261 1.00 23.40 ? 4186 HOH A O 1 HETATM 7192 O O . HOH O 6 . ? -18.106 -26.924 45.858 1.00 21.60 ? 4187 HOH A O 1 HETATM 7193 O O . HOH O 6 . ? -21.063 2.051 38.557 1.00 28.51 ? 4188 HOH A O 1 HETATM 7194 O O . HOH O 6 . ? -0.745 -20.698 15.654 1.00 21.31 ? 4189 HOH A O 1 HETATM 7195 O O . HOH O 6 . ? -33.300 9.070 41.895 1.00 39.80 ? 4190 HOH A O 1 HETATM 7196 O O . HOH O 6 . ? 3.912 -48.675 59.331 1.00 30.27 ? 4191 HOH A O 1 HETATM 7197 O O . HOH O 6 . ? -11.407 -4.135 0.395 1.00 33.11 ? 4192 HOH A O 1 HETATM 7198 O O . HOH O 6 . ? -8.971 -31.294 60.265 1.00 25.70 ? 4193 HOH A O 1 HETATM 7199 O O . HOH O 6 . ? -12.937 -28.829 24.018 1.00 33.19 ? 4194 HOH A O 1 HETATM 7200 O O . HOH O 6 . ? 1.491 -10.572 -0.165 1.00 33.25 ? 4195 HOH A O 1 HETATM 7201 O O . HOH O 6 . ? -8.753 -8.552 67.379 1.00 25.06 ? 4196 HOH A O 1 HETATM 7202 O O . HOH O 6 . ? -6.000 -28.516 38.225 1.00 31.77 ? 4197 HOH A O 1 HETATM 7203 O O . HOH O 6 . ? -20.925 -23.246 10.853 1.00 25.02 ? 4198 HOH A O 1 HETATM 7204 O O . HOH O 6 . ? 6.105 -7.586 54.735 1.00 35.08 ? 4199 HOH A O 1 HETATM 7205 O O . HOH O 6 . ? -18.589 -28.635 41.962 1.00 42.83 ? 4200 HOH A O 1 HETATM 7206 O O . HOH O 6 . ? -12.073 15.262 24.256 1.00 21.95 ? 4201 HOH A O 1 HETATM 7207 O O . HOH O 6 . ? -43.021 -0.814 30.470 1.00 23.74 ? 4202 HOH A O 1 HETATM 7208 O O . HOH O 6 . ? -3.022 -43.954 62.374 1.00 29.19 ? 4203 HOH A O 1 HETATM 7209 O O . HOH O 6 . ? 6.272 -4.646 49.233 1.00 31.76 ? 4204 HOH A O 1 HETATM 7210 O O . HOH O 6 . ? 2.642 -7.767 51.773 1.00 21.97 ? 4205 HOH A O 1 HETATM 7211 O O . HOH O 6 . ? 4.938 -15.312 71.863 1.00 22.39 ? 4206 HOH A O 1 HETATM 7212 O O . HOH O 6 . ? 4.512 9.764 21.286 1.00 30.64 ? 4207 HOH A O 1 HETATM 7213 O O . HOH O 6 . ? 4.788 -6.356 50.565 1.00 25.87 ? 4208 HOH A O 1 HETATM 7214 O O . HOH O 6 . ? 20.306 -7.181 36.240 1.00 26.47 ? 4209 HOH A O 1 HETATM 7215 O O . HOH O 6 . ? -49.809 6.934 28.599 1.00 27.74 ? 4210 HOH A O 1 HETATM 7216 O O . HOH O 6 . ? 18.697 0.629 24.392 1.00 24.28 ? 4211 HOH A O 1 HETATM 7217 O O . HOH O 6 . ? -15.731 -5.684 2.859 1.00 27.33 ? 4212 HOH A O 1 HETATM 7218 O O . HOH O 6 . ? -20.570 4.060 37.015 1.00 41.26 ? 4213 HOH A O 1 HETATM 7219 O O . HOH O 6 . ? -29.333 -8.728 45.545 1.00 27.29 ? 4214 HOH A O 1 HETATM 7220 O O . HOH O 6 . ? -1.988 -22.514 16.918 1.00 28.40 ? 4215 HOH A O 1 HETATM 7221 O O . HOH O 6 . ? -25.923 -1.198 41.789 1.00 35.95 ? 4216 HOH A O 1 HETATM 7222 O O . HOH O 6 . ? -4.591 -16.619 5.372 1.00 38.36 ? 4217 HOH A O 1 HETATM 7223 O O . HOH O 6 . ? 4.884 -8.289 -0.465 1.00 38.24 ? 4218 HOH A O 1 HETATM 7224 O O . HOH O 6 . ? -9.308 2.438 58.448 1.00 28.38 ? 4219 HOH A O 1 HETATM 7225 O O . HOH O 6 . ? -19.398 -1.623 42.205 1.00 26.80 ? 4220 HOH A O 1 HETATM 7226 O O . HOH O 6 . ? -22.616 -8.443 67.379 1.00 39.98 ? 4221 HOH A O 1 HETATM 7227 O O . HOH O 6 . ? -15.891 -36.095 49.361 1.00 26.13 ? 4222 HOH A O 1 HETATM 7228 O O . HOH O 6 . ? -24.102 20.643 20.791 1.00 34.11 ? 4223 HOH A O 1 HETATM 7229 O O . HOH O 6 . ? 6.833 -8.021 50.616 1.00 23.66 ? 4224 HOH A O 1 HETATM 7230 O O . HOH O 6 . ? 15.556 -0.354 19.217 1.00 25.53 ? 4225 HOH A O 1 HETATM 7231 O O . HOH O 6 . ? -24.772 20.910 39.204 1.00 30.51 ? 4226 HOH A O 1 HETATM 7232 O O . HOH O 6 . ? -15.759 -37.571 47.626 1.00 23.32 ? 4227 HOH A O 1 HETATM 7233 O O . HOH O 6 . ? -9.912 -0.649 53.950 1.00 37.85 ? 4228 HOH A O 1 HETATM 7234 O O . HOH O 6 . ? -25.024 -26.422 14.280 1.00 34.49 ? 4229 HOH A O 1 HETATM 7235 O O . HOH O 6 . ? 0.354 -0.894 51.425 1.00 33.69 ? 4230 HOH A O 1 HETATM 7236 O O . HOH O 6 . ? -26.531 8.281 21.337 1.00 33.74 ? 4231 HOH A O 1 HETATM 7237 O O . HOH O 6 . ? 5.176 -47.089 51.229 1.00 40.51 ? 4232 HOH A O 1 HETATM 7238 O O . HOH O 6 . ? -11.174 -4.576 37.940 1.00 27.75 ? 4233 HOH A O 1 HETATM 7239 O O . HOH O 6 . ? 4.229 -21.170 76.440 1.00 30.24 ? 4234 HOH A O 1 HETATM 7240 O O . HOH O 6 . ? -8.573 -26.462 11.795 1.00 24.48 ? 4235 HOH A O 1 HETATM 7241 O O . HOH O 6 . ? 20.428 -11.085 15.641 1.00 25.61 ? 4236 HOH A O 1 HETATM 7242 O O . HOH O 6 . ? -2.582 -14.939 5.083 1.00 32.89 ? 4237 HOH A O 1 HETATM 7243 O O . HOH O 6 . ? -19.662 -25.356 15.086 1.00 34.50 ? 4238 HOH A O 1 HETATM 7244 O O . HOH O 6 . ? -27.547 10.339 20.198 1.00 30.29 ? 4239 HOH A O 1 HETATM 7245 O O . HOH O 6 . ? 4.049 -6.475 1.269 1.00 26.39 ? 4240 HOH A O 1 HETATM 7246 O O . HOH O 6 . ? -20.024 2.836 12.872 1.00 31.19 ? 4241 HOH A O 1 HETATM 7247 O O . HOH O 6 . ? -20.212 18.921 17.720 1.00 34.26 ? 4242 HOH A O 1 HETATM 7248 O O . HOH O 6 . ? 25.270 -14.150 25.048 1.00 42.91 ? 4243 HOH A O 1 HETATM 7249 O O . HOH O 6 . ? -44.741 -3.393 27.460 1.00 36.10 ? 4244 HOH A O 1 HETATM 7250 O O . HOH O 6 . ? -21.825 -23.288 39.252 1.00 37.01 ? 4245 HOH A O 1 HETATM 7251 O O . HOH O 6 . ? -45.576 -0.044 17.887 1.00 44.24 ? 4246 HOH A O 1 HETATM 7252 O O . HOH O 6 . ? -4.127 2.854 38.687 1.00 21.57 ? 4247 HOH A O 1 HETATM 7253 O O . HOH O 6 . ? -29.778 -20.313 38.054 1.00 47.45 ? 4248 HOH A O 1 HETATM 7254 O O . HOH O 6 . ? -32.421 27.382 25.826 1.00 36.84 ? 4249 HOH A O 1 HETATM 7255 O O . HOH O 6 . ? -27.578 -18.535 29.767 1.00 31.42 ? 4250 HOH A O 1 HETATM 7256 O O . HOH O 6 . ? 13.857 -17.511 51.094 1.00 22.08 ? 4251 HOH A O 1 HETATM 7257 O O . HOH O 6 . ? 0.537 2.625 34.136 1.00 32.80 ? 4252 HOH A O 1 HETATM 7258 O O . HOH O 6 . ? 18.393 -1.448 16.179 1.00 27.00 ? 4253 HOH A O 1 HETATM 7259 O O . HOH O 6 . ? -48.180 15.173 36.168 1.00 44.11 ? 4254 HOH A O 1 HETATM 7260 O O . HOH O 6 . ? 11.641 -12.389 56.107 1.00 24.65 ? 4255 HOH A O 1 HETATM 7261 O O . HOH O 6 . ? -8.854 -33.465 43.064 1.00 40.76 ? 4256 HOH A O 1 HETATM 7262 O O . HOH O 6 . ? -20.895 -2.220 46.914 1.00 20.61 ? 4257 HOH A O 1 HETATM 7263 O O . HOH O 6 . ? -25.771 16.706 20.383 1.00 46.63 ? 4258 HOH A O 1 HETATM 7264 O O . HOH O 6 . ? 6.808 -11.777 69.920 1.00 31.03 ? 4259 HOH A O 1 HETATM 7265 O O . HOH O 6 . ? -24.258 24.143 35.479 1.00 28.10 ? 4260 HOH A O 1 HETATM 7266 O O . HOH O 6 . ? -42.253 8.339 34.230 1.00 42.00 ? 4261 HOH A O 1 HETATM 7267 O O . HOH O 6 . ? -34.414 -11.399 23.905 1.00 41.07 ? 4262 HOH A O 1 HETATM 7268 O O . HOH O 6 . ? -0.969 -29.112 35.890 1.00 22.80 ? 4263 HOH A O 1 HETATM 7269 O O . HOH O 6 . ? -16.765 -3.275 71.099 1.00 73.80 ? 4264 HOH A O 1 HETATM 7270 O O . HOH O 6 . ? -0.158 -20.888 24.822 1.00 25.49 ? 4265 HOH A O 1 HETATM 7271 O O . HOH O 6 . ? -40.093 8.939 35.396 1.00 35.46 ? 4266 HOH A O 1 HETATM 7272 O O . HOH O 6 . ? -27.292 -8.838 11.535 1.00 31.75 ? 4267 HOH A O 1 HETATM 7273 O O . HOH O 6 . ? 12.176 -13.709 21.399 1.00 28.81 ? 4268 HOH A O 1 HETATM 7274 O O . HOH O 6 . ? -28.638 17.625 40.462 1.00 46.89 ? 4269 HOH A O 1 HETATM 7275 O O . HOH O 6 . ? 13.090 -21.516 49.575 1.00 23.25 ? 4270 HOH A O 1 HETATM 7276 O O . HOH O 6 . ? 10.143 -15.345 25.768 1.00 24.98 ? 4271 HOH A O 1 HETATM 7277 O O . HOH O 6 . ? 11.349 7.063 23.764 1.00 60.80 ? 4272 HOH A O 1 HETATM 7278 O O . HOH O 6 . ? 30.227 -6.752 35.949 1.00 41.16 ? 4273 HOH A O 1 HETATM 7279 O O . HOH O 6 . ? -17.099 -37.794 52.290 1.00 40.36 ? 4274 HOH A O 1 HETATM 7280 O O . HOH O 6 . ? -18.714 -3.011 66.881 1.00 52.66 ? 4275 HOH A O 1 HETATM 7281 O O . HOH O 6 . ? 4.310 -11.883 36.231 1.00 24.57 ? 4276 HOH A O 1 HETATM 7282 O O . HOH O 6 . ? -8.015 1.663 53.144 1.00 25.81 ? 4277 HOH A O 1 HETATM 7283 O O . HOH O 6 . ? 7.968 -15.617 73.959 1.00 31.99 ? 4278 HOH A O 1 HETATM 7284 O O . HOH O 6 . ? -5.958 -3.631 33.207 1.00 35.86 ? 4279 HOH A O 1 HETATM 7285 O O . HOH O 6 . ? -13.930 -35.796 43.969 1.00 37.16 ? 4280 HOH A O 1 HETATM 7286 O O . HOH O 6 . ? -21.100 4.010 34.662 1.00 35.30 ? 4281 HOH A O 1 HETATM 7287 O O . HOH O 6 . ? -14.025 11.813 5.945 1.00 36.89 ? 4282 HOH A O 1 HETATM 7288 O O . HOH O 6 . ? -22.125 -15.694 7.777 1.00 25.27 ? 4283 HOH A O 1 HETATM 7289 O O . HOH O 6 . ? -0.079 -32.623 44.868 1.00 32.99 ? 4284 HOH A O 1 HETATM 7290 O O . HOH O 6 . ? -9.410 10.526 20.748 1.00 27.25 ? 4285 HOH A O 1 HETATM 7291 O O . HOH O 6 . ? -14.816 -2.414 52.317 1.00 36.36 ? 4286 HOH A O 1 HETATM 7292 O O . HOH O 6 . ? -21.682 -25.040 13.436 1.00 33.11 ? 4287 HOH A O 1 HETATM 7293 O O . HOH O 6 . ? 12.423 -37.769 57.625 1.00 49.52 ? 4288 HOH A O 1 HETATM 7294 O O . HOH O 6 . ? -8.296 4.315 62.418 1.00 28.83 ? 4289 HOH A O 1 HETATM 7295 O O . HOH O 6 . ? -10.363 -19.494 11.276 1.00 26.03 ? 4290 HOH A O 1 HETATM 7296 O O . HOH O 6 . ? 7.329 -7.583 68.809 1.00 29.52 ? 4291 HOH A O 1 HETATM 7297 O O . HOH O 6 . ? -40.835 2.266 19.776 1.00 33.22 ? 4292 HOH A O 1 HETATM 7298 O O . HOH O 6 . ? -33.239 6.169 42.401 1.00 35.23 ? 4293 HOH A O 1 HETATM 7299 O O . HOH O 6 . ? -33.247 -23.868 25.927 1.00 41.25 ? 4294 HOH A O 1 HETATM 7300 O O . HOH O 6 . ? 10.030 -38.768 57.561 1.00 51.82 ? 4295 HOH A O 1 HETATM 7301 O O . HOH O 6 . ? 8.693 -14.282 9.866 1.00 31.52 ? 4296 HOH A O 1 HETATM 7302 O O . HOH O 6 . ? -18.104 -4.492 2.536 1.00 31.52 ? 4297 HOH A O 1 HETATM 7303 O O . HOH O 6 . ? -4.243 2.103 60.479 1.00 26.43 ? 4298 HOH A O 1 HETATM 7304 O O . HOH O 6 . ? 10.633 -31.202 40.170 1.00 28.17 ? 4299 HOH A O 1 HETATM 7305 O O . HOH O 6 . ? -16.604 -27.384 19.383 1.00 27.77 ? 4300 HOH A O 1 HETATM 7306 O O . HOH O 6 . ? -41.477 -5.957 37.765 1.00 35.14 ? 4301 HOH A O 1 HETATM 7307 O O . HOH O 6 . ? -31.563 -16.256 47.884 1.00 37.29 ? 4302 HOH A O 1 HETATM 7308 O O . HOH O 6 . ? 27.366 -6.994 21.317 1.00 35.82 ? 4303 HOH A O 1 HETATM 7309 O O . HOH O 6 . ? -48.161 6.203 20.812 1.00 34.17 ? 4304 HOH A O 1 HETATM 7310 O O . HOH O 6 . ? -8.385 -24.569 24.268 1.00 30.65 ? 4305 HOH A O 1 HETATM 7311 O O . HOH O 6 . ? 0.740 -13.671 45.197 1.00 27.52 ? 4306 HOH A O 1 HETATM 7312 O O . HOH O 6 . ? -1.071 -17.569 8.262 1.00 26.86 ? 4307 HOH A O 1 HETATM 7313 O O . HOH O 6 . ? -16.748 14.348 42.008 1.00 35.04 ? 4308 HOH A O 1 HETATM 7314 O O . HOH O 6 . ? -3.315 -5.008 -0.426 1.00 39.45 ? 4309 HOH A O 1 HETATM 7315 O O . HOH O 6 . ? 21.803 -21.363 35.490 1.00 28.25 ? 4310 HOH A O 1 HETATM 7316 O O . HOH O 6 . ? -6.173 -40.431 49.296 1.00 22.31 ? 4311 HOH A O 1 HETATM 7317 O O . HOH O 6 . ? -37.195 -14.475 24.105 1.00 41.65 ? 4312 HOH A O 1 HETATM 7318 O O . HOH O 6 . ? -14.414 -20.007 58.039 1.00 23.01 ? 4313 HOH A O 1 HETATM 7319 O O . HOH O 6 . ? -9.230 -5.661 0.776 1.00 38.67 ? 4314 HOH A O 1 HETATM 7320 O O . HOH O 6 . ? -9.181 5.755 17.211 1.00 34.10 ? 4315 HOH A O 1 HETATM 7321 O O . HOH O 6 . ? 13.478 4.876 33.222 1.00 37.29 ? 4316 HOH A O 1 HETATM 7322 O O . HOH O 6 . ? -5.629 8.804 41.068 1.00 39.63 ? 4317 HOH A O 1 HETATM 7323 O O . HOH O 6 . ? -15.084 12.431 41.296 1.00 45.10 ? 4318 HOH A O 1 HETATM 7324 O O . HOH O 6 . ? 11.959 2.794 8.106 1.00 26.48 ? 4319 HOH A O 1 HETATM 7325 O O . HOH O 6 . ? -10.446 -14.731 3.227 1.00 34.30 ? 4320 HOH A O 1 HETATM 7326 O O . HOH O 6 . ? -3.673 -29.377 37.278 1.00 41.69 ? 4321 HOH A O 1 HETATM 7327 O O . HOH O 6 . ? 18.171 -33.681 37.856 1.00 32.29 ? 4322 HOH A O 1 HETATM 7328 O O . HOH O 6 . ? 14.168 2.793 35.559 1.00 32.07 ? 4323 HOH A O 1 HETATM 7329 O O . HOH O 6 . ? -47.921 10.158 21.226 1.00 33.53 ? 4324 HOH A O 1 HETATM 7330 O O . HOH O 6 . ? -15.144 20.963 39.862 1.00 26.12 ? 4325 HOH A O 1 HETATM 7331 O O . HOH O 6 . ? 1.594 8.723 11.816 1.00 32.52 ? 4326 HOH A O 1 HETATM 7332 O O . HOH O 6 . ? 2.051 10.386 22.178 1.00 30.36 ? 4327 HOH A O 1 HETATM 7333 O O . HOH O 6 . ? 7.460 -8.020 62.917 1.00 30.81 ? 4328 HOH A O 1 HETATM 7334 O O . HOH O 6 . ? -17.542 -20.603 65.551 1.00 44.50 ? 4329 HOH A O 1 HETATM 7335 O O . HOH O 6 . ? -0.102 -23.401 24.023 1.00 26.90 ? 4330 HOH A O 1 HETATM 7336 O O . HOH O 6 . ? 7.892 -11.287 7.657 1.00 32.75 ? 4331 HOH A O 1 HETATM 7337 O O . HOH O 6 . ? -8.835 -17.747 4.389 1.00 29.70 ? 4332 HOH A O 1 HETATM 7338 O O . HOH O 6 . ? 20.091 -20.103 17.080 1.00 32.67 ? 4333 HOH A O 1 HETATM 7339 O O . HOH O 6 . ? 6.887 -14.051 7.940 1.00 29.23 ? 4334 HOH A O 1 HETATM 7340 O O . HOH O 6 . ? -32.873 -6.554 18.274 1.00 54.31 ? 4335 HOH A O 1 HETATM 7341 O O . HOH O 6 . ? -27.254 -4.463 43.364 1.00 29.04 ? 4336 HOH A O 1 HETATM 7342 O O . HOH O 6 . ? 0.393 -9.934 12.209 1.00 27.42 ? 4337 HOH A O 1 HETATM 7343 O O . HOH O 6 . ? -7.405 -4.726 -0.867 1.00 45.88 ? 4338 HOH A O 1 HETATM 7344 O O . HOH O 6 . ? -18.743 26.658 29.185 1.00 41.01 ? 4339 HOH A O 1 HETATM 7345 O O . HOH O 6 . ? -26.042 -20.713 17.388 1.00 31.62 ? 4340 HOH A O 1 HETATM 7346 O O . HOH O 6 . ? 10.834 6.605 30.897 1.00 30.15 ? 4341 HOH A O 1 HETATM 7347 O O . HOH O 6 . ? 5.535 11.629 19.899 1.00 46.03 ? 4342 HOH A O 1 HETATM 7348 O O . HOH O 6 . ? -16.672 -13.706 69.621 1.00 48.12 ? 4343 HOH A O 1 HETATM 7349 O O . HOH O 6 . ? -33.060 4.207 41.228 1.00 34.83 ? 4344 HOH A O 1 HETATM 7350 O O . HOH O 6 . ? -27.084 -19.949 14.679 1.00 37.16 ? 4345 HOH A O 1 HETATM 7351 O O . HOH O 6 . ? 9.314 4.221 4.523 1.00 40.17 ? 4346 HOH A O 1 HETATM 7352 O O . HOH O 6 . ? 12.912 -32.615 40.233 1.00 29.15 ? 4347 HOH A O 1 HETATM 7353 O O . HOH O 6 . ? 16.175 -19.136 46.503 1.00 39.54 ? 4348 HOH A O 1 HETATM 7354 O O . HOH O 6 . ? -0.123 -0.738 53.894 1.00 41.14 ? 4349 HOH A O 1 HETATM 7355 O O . HOH O 6 . ? -14.979 -26.988 58.730 1.00 25.87 ? 4350 HOH A O 1 HETATM 7356 O O . HOH O 6 . ? -28.150 -21.804 13.643 1.00 43.95 ? 4351 HOH A O 1 HETATM 7357 O O . HOH O 6 . ? 5.796 -13.688 20.417 1.00 20.64 ? 4352 HOH A O 1 HETATM 7358 O O . HOH O 6 . ? -3.183 -15.840 21.346 1.00 17.63 ? 4353 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 ? ? ? A . n A 1 2 ALA 2 2 ? ? ? A . n A 1 3 GLU 3 3 ? ? ? A . n A 1 4 CYS 4 4 ? ? ? A . n A 1 5 PRO 5 5 ? ? ? A . n A 1 6 VAL 6 6 ? ? ? A . n A 1 7 VAL 7 7 7 VAL VAL A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 GLU 9 9 9 GLU GLU A . n A 1 10 LEU 10 10 10 LEU LEU A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 ARG 12 12 12 ARG ARG A . n A 1 13 ILE 13 13 13 ILE ILE A . n A 1 14 ASN 14 14 14 ASN ASN A . n A 1 15 CYS 15 15 15 CYS CYS A . n A 1 16 ILE 16 16 16 ILE ILE A . n A 1 17 PRO 17 17 17 PRO PRO A . n A 1 18 ASP 18 18 18 ASP ASP A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 PRO 20 20 20 PRO PRO A . n A 1 21 PRO 21 21 21 PRO PRO A . n A 1 22 THR 22 22 22 THR THR A . n A 1 23 LYS 23 23 23 LYS LYS A . n A 1 24 ALA 24 24 24 ALA ALA A . n A 1 25 THR 25 25 25 THR THR A . n A 1 26 CYS 26 26 26 CYS CYS A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 GLN 28 28 28 GLN GLN A . n A 1 29 ARG 29 29 29 ARG ARG A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 CYS 32 32 32 CYS CYS A . n A 1 33 TRP 33 33 33 TRP TRP A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 PRO 35 35 35 PRO PRO A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 ALA 38 38 38 ALA ALA A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 SER 40 40 40 SER SER A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 TRP 43 43 43 TRP TRP A . n A 1 44 CYS 44 44 44 CYS CYS A . n A 1 45 TYR 45 45 45 TYR TYR A . n A 1 46 TYR 46 46 46 TYR TYR A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 ASN 49 49 49 ASN ASN A . n A 1 50 HIS 50 50 50 HIS HIS A . n A 1 51 SER 51 51 51 SER SER A . n A 1 52 TYR 52 52 52 TYR TYR A . n A 1 53 HIS 53 53 53 HIS HIS A . n A 1 54 VAL 54 54 54 VAL VAL A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 LEU 58 58 58 LEU LEU A . n A 1 59 VAL 59 59 59 VAL VAL A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 THR 61 61 61 THR THR A . n A 1 62 ASN 62 62 62 ASN ASN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 PHE 65 65 65 PHE PHE A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ALA 67 67 67 ALA ALA A . n A 1 68 ARG 68 68 68 ARG ARG A . n A 1 69 LEU 69 69 69 LEU LEU A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 ASN 71 71 71 ASN ASN A . n A 1 72 LEU 72 72 72 LEU LEU A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 SER 74 74 74 SER SER A . n A 1 75 SER 75 75 75 SER SER A . n A 1 76 PRO 76 76 76 PRO PRO A . n A 1 77 VAL 77 77 77 VAL VAL A . n A 1 78 PHE 78 78 78 PHE PHE A . n A 1 79 GLY 79 79 79 GLY GLY A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 ASN 81 81 81 ASN ASN A . n A 1 82 VAL 82 82 82 VAL VAL A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 LEU 86 86 86 LEU LEU A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 THR 88 88 88 THR THR A . n A 1 89 ALA 89 89 89 ALA ALA A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 TYR 91 91 91 TYR TYR A . n A 1 92 GLN 92 92 92 GLN GLN A . n A 1 93 THR 93 93 93 THR THR A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 ASN 95 95 95 ASN ASN A . n A 1 96 ARG 96 96 96 ARG ARG A . n A 1 97 PHE 97 97 97 PHE PHE A . n A 1 98 HIS 98 98 98 HIS HIS A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 LYS 100 100 100 LYS LYS A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 THR 102 102 102 THR THR A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 ARG 108 108 108 ARG ARG A . n A 1 109 PHE 109 109 109 PHE PHE A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 PRO 112 112 112 PRO PRO A . n A 1 113 HIS 113 113 113 HIS HIS A . n A 1 114 GLU 114 114 114 GLU GLU A . n A 1 115 HIS 115 115 115 HIS HIS A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 GLN 117 117 117 GLN GLN A . n A 1 118 SER 118 118 118 SER SER A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 ASN 122 122 122 ASN ASN A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 ALA 124 124 124 ALA ALA A . n A 1 125 ALA 125 125 125 ALA ALA A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 TYR 129 129 129 TYR TYR A . n A 1 130 GLN 130 130 130 GLN GLN A . n A 1 131 VAL 131 131 131 VAL VAL A . n A 1 132 GLU 132 132 132 GLU GLU A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 GLN 136 136 136 GLN GLN A . n A 1 137 PRO 137 137 137 PRO PRO A . n A 1 138 PHE 138 138 138 PHE PHE A . n A 1 139 SER 139 139 139 SER SER A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 LYS 141 141 141 LYS LYS A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 THR 143 143 143 THR THR A . n A 1 144 ARG 144 144 144 ARG ARG A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 ASN 147 147 147 ASN ASN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 ARG 149 149 149 ARG ARG A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 SER 154 154 154 SER SER A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 ILE 156 156 156 ILE ILE A . n A 1 157 GLY 157 157 157 GLY GLY A . n A 1 158 PRO 158 158 158 PRO PRO A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LEU 160 160 160 LEU LEU A . n A 1 161 PHE 161 161 161 PHE PHE A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 ASP 163 163 163 ASP ASP A . n A 1 164 GLN 164 164 164 GLN GLN A . n A 1 165 PHE 165 165 165 PHE PHE A . n A 1 166 LEU 166 166 166 LEU LEU A . n A 1 167 GLN 167 167 167 GLN GLN A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 THR 170 170 170 THR THR A . n A 1 171 ARG 171 171 171 ARG ARG A . n A 1 172 LEU 172 172 172 LEU LEU A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 THR 175 175 175 THR THR A . n A 1 176 ASN 176 176 176 ASN ASN A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TYR 178 178 178 TYR TYR A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLY 181 181 181 GLY GLY A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 HIS 183 183 183 HIS HIS A . n A 1 184 VAL 184 184 184 VAL VAL A . n A 1 185 HIS 185 185 185 HIS HIS A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 GLN 187 187 187 GLN GLN A . n A 1 188 TYR 188 188 188 TYR TYR A . n A 1 189 ARG 189 189 189 ARG ARG A . n A 1 190 HIS 190 190 190 HIS HIS A . n A 1 191 ASP 191 191 191 ASP ASP A . n A 1 192 MET 192 192 192 MET MET A . n A 1 193 ASN 193 193 193 ASN ASN A . n A 1 194 TRP 194 194 194 TRP TRP A . n A 1 195 LYS 195 195 195 LYS LYS A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 TRP 197 197 197 TRP TRP A . n A 1 198 PRO 198 198 198 PRO PRO A . n A 1 199 ILE 199 199 199 ILE ILE A . n A 1 200 PHE 200 200 200 PHE PHE A . n A 1 201 ASN 201 201 201 ASN ASN A . n A 1 202 ARG 202 202 202 ARG ARG A . n A 1 203 ASP 203 203 203 ASP ASP A . n A 1 204 THR 204 204 204 THR THR A . n A 1 205 THR 205 205 205 THR THR A . n A 1 206 PRO 206 206 206 PRO PRO A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 GLY 208 208 208 GLY GLY A . n A 1 209 ASN 209 209 209 ASN ASN A . n A 1 210 GLY 210 210 210 GLY GLY A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 ASN 212 212 212 ASN ASN A . n A 1 213 LEU 213 213 213 LEU LEU A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 GLY 215 215 215 GLY GLY A . n A 1 216 ALA 216 216 216 ALA ALA A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 PHE 219 219 219 PHE PHE A . n A 1 220 PHE 220 220 220 PHE PHE A . n A 1 221 LEU 221 221 221 LEU LEU A . n A 1 222 CYS 222 222 222 CYS CYS A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 GLU 224 224 224 GLU GLU A . n A 1 225 ASP 225 225 225 ASP ASP A . n A 1 226 ALA 226 226 226 ALA ALA A . n A 1 227 SER 227 227 227 SER SER A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 PHE 231 231 231 PHE PHE A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 PHE 234 234 234 PHE PHE A . n A 1 235 LEU 235 235 235 LEU LEU A . n A 1 236 MET 236 236 236 MET MET A . n A 1 237 ASN 237 237 237 ASN ASN A . n A 1 238 SER 238 238 238 SER SER A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 ALA 240 240 240 ALA ALA A . n A 1 241 MET 241 241 241 MET MET A . n A 1 242 GLU 242 242 242 GLU GLU A . n A 1 243 VAL 243 243 243 VAL VAL A . n A 1 244 VAL 244 244 244 VAL VAL A . n A 1 245 LEU 245 245 245 LEU LEU A . n A 1 246 GLN 246 246 246 GLN GLN A . n A 1 247 PRO 247 247 247 PRO PRO A . n A 1 248 ALA 248 248 248 ALA ALA A . n A 1 249 PRO 249 249 249 PRO PRO A . n A 1 250 ALA 250 250 250 ALA ALA A . n A 1 251 ILE 251 251 251 ILE ILE A . n A 1 252 THR 252 252 252 THR THR A . n A 1 253 TYR 253 253 253 TYR TYR A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 THR 255 255 255 THR THR A . n A 1 256 ILE 256 256 256 ILE ILE A . n A 1 257 GLY 257 257 257 GLY GLY A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 ILE 259 259 259 ILE ILE A . n A 1 260 LEU 260 260 260 LEU LEU A . n A 1 261 ASP 261 261 261 ASP ASP A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 TYR 263 263 263 TYR TYR A . n A 1 264 VAL 264 264 264 VAL VAL A . n A 1 265 PHE 265 265 265 PHE PHE A . n A 1 266 LEU 266 266 266 LEU LEU A . n A 1 267 GLY 267 267 267 GLY GLY A . n A 1 268 ASN 268 268 268 ASN ASN A . n A 1 269 THR 269 269 269 THR THR A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 GLN 272 272 272 GLN GLN A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 GLN 275 275 275 GLN GLN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 TYR 277 277 277 TYR TYR A . n A 1 278 LEU 278 278 278 LEU LEU A . n A 1 279 GLU 279 279 279 GLU GLU A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 ILE 281 281 281 ILE ILE A . n A 1 282 GLY 282 282 282 GLY GLY A . n A 1 283 ARG 283 283 283 ARG ARG A . n A 1 284 PRO 284 284 284 PRO PRO A . n A 1 285 ALA 285 285 285 ALA ALA A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 SER 288 288 288 SER SER A . n A 1 289 TYR 289 289 289 TYR TYR A . n A 1 290 TRP 290 290 290 TRP TRP A . n A 1 291 ALA 291 291 291 ALA ALA A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 PHE 294 294 294 PHE PHE A . n A 1 295 HIS 295 295 295 HIS HIS A . n A 1 296 LEU 296 296 296 LEU LEU A . n A 1 297 SER 297 297 297 SER SER A . n A 1 298 ARG 298 298 298 ARG ARG A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 GLU 300 300 300 GLU GLU A . n A 1 301 TYR 301 301 301 TYR TYR A . n A 1 302 GLY 302 302 302 GLY GLY A . n A 1 303 THR 303 303 303 THR THR A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 ASP 305 305 305 ASP ASP A . n A 1 306 ASN 306 306 306 ASN ASN A . n A 1 307 MET 307 307 307 MET MET A . n A 1 308 ARG 308 308 308 ARG ARG A . n A 1 309 GLU 309 309 309 GLU GLU A . n A 1 310 VAL 310 310 310 VAL VAL A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 GLU 312 312 312 GLU GLU A . n A 1 313 ARG 313 313 313 ARG ARG A . n A 1 314 ASN 314 314 314 ASN ASN A . n A 1 315 ARG 315 315 315 ARG ARG A . n A 1 316 ALA 316 316 316 ALA ALA A . n A 1 317 ALA 317 317 317 ALA ALA A . n A 1 318 GLN 318 318 318 GLN GLN A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 PRO 320 320 320 PRO PRO A . n A 1 321 TYR 321 321 321 TYR TYR A . n A 1 322 ASP 322 322 322 ASP ASP A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 GLN 324 324 324 GLN GLN A . n A 1 325 HIS 325 325 325 HIS HIS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 ASP 327 327 327 ASP ASP A . n A 1 328 ILE 328 328 328 ILE ILE A . n A 1 329 ASP 329 329 329 ASP ASP A . n A 1 330 TYR 330 330 330 TYR TYR A . n A 1 331 MET 331 331 331 MET MET A . n A 1 332 ASP 332 332 332 ASP ASP A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 ARG 334 334 334 ARG ARG A . n A 1 335 ARG 335 335 335 ARG ARG A . n A 1 336 ASP 336 336 336 ASP ASP A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 THR 338 338 338 THR THR A . n A 1 339 TYR 339 339 339 TYR TYR A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 SER 341 341 341 SER SER A . n A 1 342 VAL 342 342 342 VAL VAL A . n A 1 343 ASP 343 343 343 ASP ASP A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLY 346 346 346 GLY GLY A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 PRO 348 348 348 PRO PRO A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 VAL 351 351 351 VAL VAL A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 GLU 353 353 353 GLU GLU A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 HIS 355 355 355 HIS HIS A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 ASN 357 357 357 ASN ASN A . n A 1 358 GLY 358 358 358 GLY GLY A . n A 1 359 GLN 359 359 359 GLN GLN A . n A 1 360 LYS 360 360 360 LYS LYS A . n A 1 361 LEU 361 361 361 LEU LEU A . n A 1 362 VAL 362 362 362 VAL VAL A . n A 1 363 ILE 363 363 363 ILE ILE A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 VAL 365 365 365 VAL VAL A . n A 1 366 ASP 366 366 366 ASP ASP A . n A 1 367 PRO 367 367 367 PRO PRO A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 SER 370 370 370 SER SER A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 ASN 372 372 372 ASN ASN A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 SER 375 375 375 SER SER A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 LYS 377 377 377 LYS LYS A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 TYR 379 379 379 TYR TYR A . n A 1 380 GLY 380 380 380 GLY GLY A . n A 1 381 PRO 381 381 381 PRO PRO A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 ASP 383 383 383 ASP ASP A . n A 1 384 ARG 384 384 384 ARG ARG A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 SER 386 386 386 SER SER A . n A 1 387 ASP 387 387 387 ASP ASP A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 LYS 389 389 389 LYS LYS A . n A 1 390 ILE 390 390 390 ILE ILE A . n A 1 391 TRP 391 391 391 TRP TRP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 ASN 393 393 393 ASN ASN A . n A 1 394 SER 394 394 394 SER SER A . n A 1 395 SER 395 395 395 SER SER A . n A 1 396 ASP 396 396 396 ASP ASP A . n A 1 397 GLY 397 397 397 GLY GLY A . n A 1 398 VAL 398 398 398 VAL VAL A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 PRO 400 400 400 PRO PRO A . n A 1 401 LEU 401 401 401 LEU LEU A . n A 1 402 ILE 402 402 402 ILE ILE A . n A 1 403 GLY 403 403 403 GLY GLY A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 VAL 405 405 405 VAL VAL A . n A 1 406 TRP 406 406 406 TRP TRP A . n A 1 407 PRO 407 407 407 PRO PRO A . n A 1 408 GLY 408 408 408 GLY GLY A . n A 1 409 GLN 409 409 409 GLN GLN A . n A 1 410 THR 410 410 410 THR THR A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 PHE 412 412 412 PHE PHE A . n A 1 413 PRO 413 413 413 PRO PRO A . n A 1 414 ASP 414 414 414 ASP ASP A . n A 1 415 TYR 415 415 415 TYR TYR A . n A 1 416 THR 416 416 416 THR THR A . n A 1 417 ASN 417 417 417 ASN ASN A . n A 1 418 PRO 418 418 418 PRO PRO A . n A 1 419 ASN 419 419 419 ASN ASN A . n A 1 420 CYS 420 420 420 CYS CYS A . n A 1 421 ALA 421 421 421 ALA ALA A . n A 1 422 VAL 422 422 422 VAL VAL A . n A 1 423 TRP 423 423 423 TRP TRP A . n A 1 424 TRP 424 424 424 TRP TRP A . n A 1 425 THR 425 425 425 THR THR A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 GLU 427 427 427 GLU GLU A . n A 1 428 PHE 428 428 428 PHE PHE A . n A 1 429 GLU 429 429 429 GLU GLU A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 PHE 431 431 431 PHE PHE A . n A 1 432 HIS 432 432 432 HIS HIS A . n A 1 433 ASN 433 433 433 ASN ASN A . n A 1 434 GLN 434 434 434 GLN GLN A . n A 1 435 VAL 435 435 435 VAL VAL A . n A 1 436 GLU 436 436 436 GLU GLU A . n A 1 437 PHE 437 437 437 PHE PHE A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 ILE 440 440 440 ILE ILE A . n A 1 441 TRP 441 441 441 TRP TRP A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 MET 444 444 444 MET MET A . n A 1 445 ASN 445 445 445 ASN ASN A . n A 1 446 GLU 446 446 446 GLU GLU A . n A 1 447 VAL 447 447 447 VAL VAL A . n A 1 448 SER 448 448 448 SER SER A . n A 1 449 ASN 449 449 449 ASN ASN A . n A 1 450 PHE 450 450 450 PHE PHE A . n A 1 451 VAL 451 451 451 VAL VAL A . n A 1 452 ASP 452 452 452 ASP ASP A . n A 1 453 GLY 453 453 453 GLY GLY A . n A 1 454 SER 454 454 454 SER SER A . n A 1 455 VAL 455 455 455 VAL VAL A . n A 1 456 SER 456 456 456 SER SER A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 CYS 458 458 458 CYS CYS A . n A 1 459 SER 459 459 459 SER SER A . n A 1 460 THR 460 460 460 THR THR A . n A 1 461 ASN 461 461 461 ASN ASN A . n A 1 462 ASN 462 462 462 ASN ASN A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 ASN 464 464 464 ASN ASN A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 PRO 466 466 466 PRO PRO A . n A 1 467 PRO 467 467 467 PRO PRO A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 THR 469 469 469 THR THR A . n A 1 470 PRO 470 470 470 PRO PRO A . n A 1 471 ARG 471 471 471 ARG ARG A . n A 1 472 ILE 472 472 472 ILE ILE A . n A 1 473 LEU 473 473 473 LEU LEU A . n A 1 474 ASP 474 474 474 ASP ASP A . n A 1 475 GLY 475 475 475 GLY GLY A . n A 1 476 TYR 476 476 476 TYR TYR A . n A 1 477 LEU 477 477 477 LEU LEU A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 CYS 479 479 479 CYS CYS A . n A 1 480 LYS 480 480 480 LYS LYS A . n A 1 481 THR 481 481 481 THR THR A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 CYS 483 483 483 CYS CYS A . n A 1 484 MET 484 484 484 MET MET A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 ALA 486 486 486 ALA ALA A . n A 1 487 VAL 487 487 487 VAL VAL A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 HIS 489 489 489 HIS HIS A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 GLY 491 491 491 GLY GLY A . n A 1 492 LYS 492 492 492 LYS LYS A . n A 1 493 GLN 493 493 493 GLN GLN A . n A 1 494 TYR 494 494 494 TYR TYR A . n A 1 495 ASP 495 495 495 ASP ASP A . n A 1 496 ILE 496 496 496 ILE ILE A . n A 1 497 HIS 497 497 497 HIS HIS A . n A 1 498 ASN 498 498 498 ASN ASN A . n A 1 499 LEU 499 499 499 LEU LEU A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 GLY 501 501 501 GLY GLY A . n A 1 502 TYR 502 502 502 TYR TYR A . n A 1 503 SER 503 503 503 SER SER A . n A 1 504 MET 504 504 504 MET MET A . n A 1 505 ALA 505 505 505 ALA ALA A . n A 1 506 VAL 506 506 506 VAL VAL A . n A 1 507 ALA 507 507 507 ALA ALA A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ALA 509 509 509 ALA ALA A . n A 1 510 GLU 510 510 510 GLU GLU A . n A 1 511 ALA 511 511 511 ALA ALA A . n A 1 512 ALA 512 512 512 ALA ALA A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 THR 514 514 514 THR THR A . n A 1 515 VAL 515 515 515 VAL VAL A . n A 1 516 PHE 516 516 516 PHE PHE A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASN 518 518 518 ASN ASN A . n A 1 519 LYS 519 519 519 LYS LYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 SER 521 521 521 SER SER A . n A 1 522 PHE 522 522 522 PHE PHE A . n A 1 523 ILE 523 523 523 ILE ILE A . n A 1 524 LEU 524 524 524 LEU LEU A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 ARG 526 526 526 ARG ARG A . n A 1 527 SER 527 527 527 SER SER A . n A 1 528 THR 528 528 528 THR THR A . n A 1 529 PHE 529 529 529 PHE PHE A . n A 1 530 ALA 530 530 530 ALA ALA A . n A 1 531 GLY 531 531 531 GLY GLY A . n A 1 532 SER 532 532 532 SER SER A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 LYS 534 534 534 LYS LYS A . n A 1 535 PHE 535 535 535 PHE PHE A . n A 1 536 ALA 536 536 536 ALA ALA A . n A 1 537 ALA 537 537 537 ALA ALA A . n A 1 538 HIS 538 538 538 HIS HIS A . n A 1 539 TRP 539 539 539 TRP TRP A . n A 1 540 LEU 540 540 540 LEU LEU A . n A 1 541 GLY 541 541 541 GLY GLY A . n A 1 542 ASP 542 542 542 ASP ASP A . n A 1 543 ASN 543 543 543 ASN ASN A . n A 1 544 THR 544 544 544 THR THR A . n A 1 545 ALA 545 545 545 ALA ALA A . n A 1 546 THR 546 546 546 THR THR A . n A 1 547 TRP 547 547 547 TRP TRP A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ASP 549 549 549 ASP ASP A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 ARG 551 551 551 ARG ARG A . n A 1 552 TRP 552 552 552 TRP TRP A . n A 1 553 SER 553 553 553 SER SER A . n A 1 554 ILE 554 554 554 ILE ILE A . n A 1 555 PRO 555 555 555 PRO PRO A . n A 1 556 GLY 556 556 556 GLY GLY A . n A 1 557 VAL 557 557 557 VAL VAL A . n A 1 558 LEU 558 558 558 LEU LEU A . n A 1 559 GLU 559 559 559 GLU GLU A . n A 1 560 PHE 560 560 560 PHE PHE A . n A 1 561 ASN 561 561 561 ASN ASN A . n A 1 562 LEU 562 562 562 LEU LEU A . n A 1 563 PHE 563 563 563 PHE PHE A . n A 1 564 GLY 564 564 564 GLY GLY A . n A 1 565 ILE 565 565 565 ILE ILE A . n A 1 566 PRO 566 566 566 PRO PRO A . n A 1 567 MET 567 567 567 MET MET A . n A 1 568 VAL 568 568 568 VAL VAL A . n A 1 569 GLY 569 569 569 GLY GLY A . n A 1 570 PRO 570 570 570 PRO PRO A . n A 1 571 ASP 571 571 571 ASP ASP A . n A 1 572 ILE 572 572 572 ILE ILE A . n A 1 573 CYS 573 573 573 CYS CYS A . n A 1 574 GLY 574 574 574 GLY GLY A . n A 1 575 PHE 575 575 575 PHE PHE A . n A 1 576 ALA 576 576 576 ALA ALA A . n A 1 577 LEU 577 577 577 LEU LEU A . n A 1 578 ASP 578 578 578 ASP ASP A . n A 1 579 THR 579 579 579 THR THR A . n A 1 580 PRO 580 580 580 PRO PRO A . n A 1 581 GLU 581 581 581 GLU GLU A . n A 1 582 GLU 582 582 582 GLU GLU A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 CYS 584 584 584 CYS CYS A . n A 1 585 ARG 585 585 585 ARG ARG A . n A 1 586 ARG 586 586 586 ARG ARG A . n A 1 587 TRP 587 587 587 TRP TRP A . n A 1 588 MET 588 588 588 MET MET A . n A 1 589 GLN 589 589 589 GLN GLN A . n A 1 590 LEU 590 590 590 LEU LEU A . n A 1 591 GLY 591 591 591 GLY GLY A . n A 1 592 ALA 592 592 592 ALA ALA A . n A 1 593 PHE 593 593 593 PHE PHE A . n A 1 594 TYR 594 594 594 TYR TYR A . n A 1 595 PRO 595 595 595 PRO PRO A . n A 1 596 PHE 596 596 596 PHE PHE A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 ARG 598 598 598 ARG ARG A . n A 1 599 ASN 599 599 599 ASN ASN A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASN 601 601 601 ASN ASN A . n A 1 602 GLY 602 602 602 GLY GLY A . n A 1 603 GLN 603 603 603 GLN GLN A . n A 1 604 GLY 604 604 604 GLY GLY A . n A 1 605 TYR 605 605 605 TYR TYR A . n A 1 606 LYS 606 606 606 LYS LYS A . n A 1 607 ASP 607 607 607 ASP ASP A . n A 1 608 GLN 608 608 608 GLN GLN A . n A 1 609 ASP 609 609 609 ASP ASP A . n A 1 610 PRO 610 610 610 PRO PRO A . n A 1 611 ALA 611 611 611 ALA ALA A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 PHE 613 613 613 PHE PHE A . n A 1 614 GLY 614 614 614 GLY GLY A . n A 1 615 ALA 615 615 615 ALA ALA A . n A 1 616 ASP 616 616 616 ASP ASP A . n A 1 617 SER 617 617 617 SER SER A . n A 1 618 LEU 618 618 618 LEU LEU A . n A 1 619 LEU 619 619 619 LEU LEU A . n A 1 620 LEU 620 620 620 LEU LEU A . n A 1 621 ASN 621 621 621 ASN ASN A . n A 1 622 SER 622 622 622 SER SER A . n A 1 623 SER 623 623 623 SER SER A . n A 1 624 ARG 624 624 624 ARG ARG A . n A 1 625 HIS 625 625 625 HIS HIS A . n A 1 626 TYR 626 626 626 TYR TYR A . n A 1 627 LEU 627 627 627 LEU LEU A . n A 1 628 ASN 628 628 628 ASN ASN A . n A 1 629 ILE 629 629 629 ILE ILE A . n A 1 630 ARG 630 630 630 ARG ARG A . n A 1 631 TYR 631 631 631 TYR TYR A . n A 1 632 THR 632 632 632 THR THR A . n A 1 633 LEU 633 633 633 LEU LEU A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 PRO 635 635 635 PRO PRO A . n A 1 636 TYR 636 636 636 TYR TYR A . n A 1 637 LEU 637 637 637 LEU LEU A . n A 1 638 TYR 638 638 638 TYR TYR A . n A 1 639 THR 639 639 639 THR THR A . n A 1 640 LEU 640 640 640 LEU LEU A . n A 1 641 PHE 641 641 641 PHE PHE A . n A 1 642 PHE 642 642 642 PHE PHE A . n A 1 643 ARG 643 643 643 ARG ARG A . n A 1 644 ALA 644 644 644 ALA ALA A . n A 1 645 HIS 645 645 645 HIS HIS A . n A 1 646 SER 646 646 646 SER SER A . n A 1 647 ARG 647 647 647 ARG ARG A . n A 1 648 GLY 648 648 648 GLY GLY A . n A 1 649 ASP 649 649 649 ASP ASP A . n A 1 650 THR 650 650 650 THR THR A . n A 1 651 VAL 651 651 651 VAL VAL A . n A 1 652 ALA 652 652 652 ALA ALA A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 PRO 654 654 654 PRO PRO A . n A 1 655 LEU 655 655 655 LEU LEU A . n A 1 656 LEU 656 656 656 LEU LEU A . n A 1 657 HIS 657 657 657 HIS HIS A . n A 1 658 GLU 658 658 658 GLU GLU A . n A 1 659 PHE 659 659 659 PHE PHE A . n A 1 660 TYR 660 660 660 TYR TYR A . n A 1 661 GLU 661 661 661 GLU GLU A . n A 1 662 ASP 662 662 662 ASP ASP A . n A 1 663 ASN 663 663 663 ASN ASN A . n A 1 664 SER 664 664 664 SER SER A . n A 1 665 THR 665 665 665 THR THR A . n A 1 666 TRP 666 666 666 TRP TRP A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 HIS 669 669 669 HIS HIS A . n A 1 670 GLN 670 670 670 GLN GLN A . n A 1 671 GLN 671 671 671 GLN GLN A . n A 1 672 PHE 672 672 672 PHE PHE A . n A 1 673 LEU 673 673 673 LEU LEU A . n A 1 674 TRP 674 674 674 TRP TRP A . n A 1 675 GLY 675 675 675 GLY GLY A . n A 1 676 PRO 676 676 676 PRO PRO A . n A 1 677 GLY 677 677 677 GLY GLY A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 LEU 679 679 679 LEU LEU A . n A 1 680 ILE 680 680 680 ILE ILE A . n A 1 681 THR 681 681 681 THR THR A . n A 1 682 PRO 682 682 682 PRO PRO A . n A 1 683 VAL 683 683 683 VAL VAL A . n A 1 684 LEU 684 684 684 LEU LEU A . n A 1 685 ASP 685 685 685 ASP ASP A . n A 1 686 GLU 686 686 686 GLU GLU A . n A 1 687 GLY 687 687 687 GLY GLY A . n A 1 688 ALA 688 688 688 ALA ALA A . n A 1 689 GLU 689 689 689 GLU GLU A . n A 1 690 LYS 690 690 690 LYS LYS A . n A 1 691 VAL 691 691 691 VAL VAL A . n A 1 692 MET 692 692 692 MET MET A . n A 1 693 ALA 693 693 693 ALA ALA A . n A 1 694 TYR 694 694 694 TYR TYR A . n A 1 695 VAL 695 695 695 VAL VAL A . n A 1 696 PRO 696 696 696 PRO PRO A . n A 1 697 ASP 697 697 697 ASP ASP A . n A 1 698 ALA 698 698 698 ALA ALA A . n A 1 699 VAL 699 699 699 VAL VAL A . n A 1 700 TRP 700 700 700 TRP TRP A . n A 1 701 TYR 701 701 701 TYR TYR A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 TYR 703 703 703 TYR TYR A . n A 1 704 GLU 704 704 704 GLU GLU A . n A 1 705 THR 705 705 705 THR THR A . n A 1 706 GLY 706 706 706 GLY GLY A . n A 1 707 SER 707 707 707 SER SER A . n A 1 708 GLN 708 708 708 GLN GLN A . n A 1 709 VAL 709 709 709 VAL VAL A . n A 1 710 ARG 710 710 710 ARG ARG A . n A 1 711 TRP 711 711 711 TRP TRP A . n A 1 712 ARG 712 712 712 ARG ARG A . n A 1 713 LYS 713 713 713 LYS LYS A . n A 1 714 GLN 714 714 714 GLN GLN A . n A 1 715 LYS 715 715 715 LYS LYS A . n A 1 716 VAL 716 716 716 VAL VAL A . n A 1 717 GLU 717 717 717 GLU GLU A . n A 1 718 MET 718 718 718 MET MET A . n A 1 719 GLU 719 719 719 GLU GLU A . n A 1 720 LEU 720 720 720 LEU LEU A . n A 1 721 PRO 721 721 721 PRO PRO A . n A 1 722 GLY 722 722 722 GLY GLY A . n A 1 723 ASP 723 723 723 ASP ASP A . n A 1 724 LYS 724 724 724 LYS LYS A . n A 1 725 ILE 725 725 725 ILE ILE A . n A 1 726 GLY 726 726 726 GLY GLY A . n A 1 727 LEU 727 727 727 LEU LEU A . n A 1 728 HIS 728 728 728 HIS HIS A . n A 1 729 LEU 729 729 729 LEU LEU A . n A 1 730 ARG 730 730 730 ARG ARG A . n A 1 731 GLY 731 731 731 GLY GLY A . n A 1 732 GLY 732 732 732 GLY GLY A . n A 1 733 TYR 733 733 733 TYR TYR A . n A 1 734 ILE 734 734 734 ILE ILE A . n A 1 735 PHE 735 735 735 PHE PHE A . n A 1 736 PRO 736 736 736 PRO PRO A . n A 1 737 THR 737 737 737 THR THR A . n A 1 738 GLN 738 738 738 GLN GLN A . n A 1 739 GLN 739 739 739 GLN GLN A . n A 1 740 PRO 740 740 740 PRO PRO A . n A 1 741 ASN 741 741 741 ASN ASN A . n A 1 742 THR 742 742 742 THR THR A . n A 1 743 THR 743 743 743 THR THR A . n A 1 744 THR 744 744 744 THR THR A . n A 1 745 LEU 745 745 745 LEU LEU A . n A 1 746 ALA 746 746 746 ALA ALA A . n A 1 747 SER 747 747 747 SER SER A . n A 1 748 ARG 748 748 748 ARG ARG A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 ASN 750 750 750 ASN ASN A . n A 1 751 PRO 751 751 751 PRO PRO A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLY 753 753 753 GLY GLY A . n A 1 754 LEU 754 754 754 LEU LEU A . n A 1 755 ILE 755 755 755 ILE ILE A . n A 1 756 ILE 756 756 756 ILE ILE A . n A 1 757 ALA 757 757 757 ALA ALA A . n A 1 758 LEU 758 758 758 LEU LEU A . n A 1 759 ASP 759 759 759 ASP ASP A . n A 1 760 GLU 760 760 760 GLU GLU A . n A 1 761 ASN 761 761 761 ASN ASN A . n A 1 762 LYS 762 762 762 LYS LYS A . n A 1 763 GLU 763 763 763 GLU GLU A . n A 1 764 ALA 764 764 764 ALA ALA A . n A 1 765 LYS 765 765 765 LYS LYS A . n A 1 766 GLY 766 766 766 GLY GLY A . n A 1 767 GLU 767 767 767 GLU GLU A . n A 1 768 LEU 768 768 768 LEU LEU A . n A 1 769 PHE 769 769 769 PHE PHE A . n A 1 770 TRP 770 770 770 TRP TRP A . n A 1 771 ASP 771 771 771 ASP ASP A . n A 1 772 ASP 772 772 772 ASP ASP A . n A 1 773 GLY 773 773 773 GLY GLY A . n A 1 774 GLU 774 774 774 GLU GLU A . n A 1 775 THR 775 775 775 THR THR A . n A 1 776 LYS 776 776 776 LYS LYS A . n A 1 777 ASP 777 777 777 ASP ASP A . n A 1 778 THR 778 778 778 THR THR A . n A 1 779 VAL 779 779 779 VAL VAL A . n A 1 780 ALA 780 780 780 ALA ALA A . n A 1 781 ASN 781 781 781 ASN ASN A . n A 1 782 LYS 782 782 782 LYS LYS A . n A 1 783 VAL 783 783 783 VAL VAL A . n A 1 784 TYR 784 784 784 TYR TYR A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 LEU 786 786 786 LEU LEU A . n A 1 787 CYS 787 787 787 CYS CYS A . n A 1 788 GLU 788 788 788 GLU GLU A . n A 1 789 PHE 789 789 789 PHE PHE A . n A 1 790 SER 790 790 790 SER SER A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 THR 792 792 792 THR THR A . n A 1 793 GLN 793 793 793 GLN GLN A . n A 1 794 ASN 794 794 794 ASN ASN A . n A 1 795 ARG 795 795 795 ARG ARG A . n A 1 796 LEU 796 796 796 LEU LEU A . n A 1 797 GLU 797 797 797 GLU GLU A . n A 1 798 VAL 798 798 798 VAL VAL A . n A 1 799 ASN 799 799 799 ASN ASN A . n A 1 800 ILE 800 800 800 ILE ILE A . n A 1 801 SER 801 801 801 SER SER A . n A 1 802 GLN 802 802 802 GLN GLN A . n A 1 803 SER 803 803 803 SER SER A . n A 1 804 THR 804 804 804 THR THR A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 LYS 806 806 806 LYS LYS A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 PRO 808 808 808 PRO PRO A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 ASN 810 810 810 ASN ASN A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 ALA 812 812 812 ALA ALA A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ASN 814 814 814 ASN ASN A . n A 1 815 GLU 815 815 815 GLU GLU A . n A 1 816 ILE 816 816 816 ILE ILE A . n A 1 817 LYS 817 817 817 LYS LYS A . n A 1 818 ILE 818 818 818 ILE ILE A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 GLY 820 820 820 GLY GLY A . n A 1 821 THR 821 821 821 THR THR A . n A 1 822 GLU 822 822 822 GLU GLU A . n A 1 823 GLU 823 823 823 GLU GLU A . n A 1 824 PRO 824 824 824 PRO PRO A . n A 1 825 SER 825 825 825 SER SER A . n A 1 826 ASN 826 826 826 ASN ASN A . n A 1 827 VAL 827 827 827 VAL VAL A . n A 1 828 THR 828 828 828 THR THR A . n A 1 829 VAL 829 829 829 VAL VAL A . n A 1 830 LYS 830 830 830 LYS LYS A . n A 1 831 HIS 831 831 831 HIS HIS A . n A 1 832 ASN 832 832 832 ASN ASN A . n A 1 833 GLY 833 833 833 GLY GLY A . n A 1 834 VAL 834 834 834 VAL VAL A . n A 1 835 PRO 835 835 835 PRO PRO A . n A 1 836 SER 836 836 836 SER SER A . n A 1 837 GLN 837 837 ? ? ? A . n A 1 838 THR 838 838 ? ? ? A . n A 1 839 SER 839 839 839 SER SER A . n A 1 840 PRO 840 840 840 PRO PRO A . n A 1 841 THR 841 841 841 THR THR A . n A 1 842 VAL 842 842 842 VAL VAL A . n A 1 843 THR 843 843 843 THR THR A . n A 1 844 TYR 844 844 844 TYR TYR A . n A 1 845 ASP 845 845 845 ASP ASP A . n A 1 846 SER 846 846 846 SER SER A . n A 1 847 ASN 847 847 847 ASN ASN A . n A 1 848 LEU 848 848 848 LEU LEU A . n A 1 849 LYS 849 849 849 LYS LYS A . n A 1 850 VAL 850 850 850 VAL VAL A . n A 1 851 ALA 851 851 851 ALA ALA A . n A 1 852 ILE 852 852 852 ILE ILE A . n A 1 853 ILE 853 853 853 ILE ILE A . n A 1 854 THR 854 854 854 THR THR A . n A 1 855 ASP 855 855 855 ASP ASP A . n A 1 856 ILE 856 856 856 ILE ILE A . n A 1 857 ASP 857 857 857 ASP ASP A . n A 1 858 LEU 858 858 858 LEU LEU A . n A 1 859 LEU 859 859 859 LEU LEU A . n A 1 860 LEU 860 860 860 LEU LEU A . n A 1 861 GLY 861 861 861 GLY GLY A . n A 1 862 GLU 862 862 862 GLU GLU A . n A 1 863 ALA 863 863 863 ALA ALA A . n A 1 864 TYR 864 864 864 TYR TYR A . n A 1 865 THR 865 865 865 THR THR A . n A 1 866 VAL 866 866 866 VAL VAL A . n A 1 867 GLU 867 867 867 GLU GLU A . n A 1 868 TRP 868 868 868 TRP TRP A . n A 1 869 ALA 869 869 869 ALA ALA A . n A 1 870 HIS 870 870 870 HIS HIS A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 2001 2001 NAG NAG A . C 2 NAG 1 2002 2002 NAG NAG A . D 3 SO4 1 4001 4001 SO4 SO4 A . E 4 3CU 1 1001 1001 3CU 3CU A . F 5 GOL 1 3001 3001 GOL GOL A . G 5 GOL 1 3002 3002 GOL GOL A . H 5 GOL 1 3003 3003 GOL GOL A . I 5 GOL 1 3004 3004 GOL GOL A . J 5 GOL 1 3005 3005 GOL GOL A . K 5 GOL 1 3006 3006 GOL GOL A . L 5 GOL 1 3007 3007 GOL GOL A . M 5 GOL 1 3008 3008 GOL GOL A . N 5 GOL 1 3009 3009 GOL GOL A . O 6 HOH 1 4002 1 HOH HOH A . O 6 HOH 2 4003 2 HOH HOH A . O 6 HOH 3 4004 3 HOH HOH A . O 6 HOH 4 4005 4 HOH HOH A . O 6 HOH 5 4006 5 HOH HOH A . O 6 HOH 6 4007 6 HOH HOH A . O 6 HOH 7 4008 7 HOH HOH A . O 6 HOH 8 4009 8 HOH HOH A . O 6 HOH 9 4010 9 HOH HOH A . O 6 HOH 10 4011 10 HOH HOH A . O 6 HOH 11 4012 11 HOH HOH A . O 6 HOH 12 4013 12 HOH HOH A . O 6 HOH 13 4014 13 HOH HOH A . O 6 HOH 14 4015 14 HOH HOH A . O 6 HOH 15 4016 15 HOH HOH A . O 6 HOH 16 4017 16 HOH HOH A . O 6 HOH 17 4018 17 HOH HOH A . O 6 HOH 18 4019 18 HOH HOH A . O 6 HOH 19 4020 19 HOH HOH A . O 6 HOH 20 4021 20 HOH HOH A . O 6 HOH 21 4022 21 HOH HOH A . O 6 HOH 22 4023 22 HOH HOH A . O 6 HOH 23 4024 23 HOH HOH A . O 6 HOH 24 4025 24 HOH HOH A . O 6 HOH 25 4026 25 HOH HOH A . O 6 HOH 26 4027 26 HOH HOH A . O 6 HOH 27 4028 27 HOH HOH A . O 6 HOH 28 4029 28 HOH HOH A . O 6 HOH 29 4030 29 HOH HOH A . O 6 HOH 30 4031 30 HOH HOH A . O 6 HOH 31 4032 31 HOH HOH A . O 6 HOH 32 4033 32 HOH HOH A . O 6 HOH 33 4034 33 HOH HOH A . O 6 HOH 34 4035 34 HOH HOH A . O 6 HOH 35 4036 35 HOH HOH A . O 6 HOH 36 4037 36 HOH HOH A . O 6 HOH 37 4038 37 HOH HOH A . O 6 HOH 38 4039 38 HOH HOH A . O 6 HOH 39 4040 39 HOH HOH A . O 6 HOH 40 4041 40 HOH HOH A . O 6 HOH 41 4042 41 HOH HOH A . O 6 HOH 42 4043 42 HOH HOH A . O 6 HOH 43 4044 43 HOH HOH A . O 6 HOH 44 4045 44 HOH HOH A . O 6 HOH 45 4046 45 HOH HOH A . O 6 HOH 46 4047 46 HOH HOH A . O 6 HOH 47 4048 47 HOH HOH A . O 6 HOH 48 4049 48 HOH HOH A . O 6 HOH 49 4050 49 HOH HOH A . O 6 HOH 50 4051 50 HOH HOH A . O 6 HOH 51 4052 51 HOH HOH A . O 6 HOH 52 4053 52 HOH HOH A . O 6 HOH 53 4054 53 HOH HOH A . O 6 HOH 54 4055 54 HOH HOH A . O 6 HOH 55 4056 55 HOH HOH A . O 6 HOH 56 4057 56 HOH HOH A . O 6 HOH 57 4058 57 HOH HOH A . O 6 HOH 58 4059 58 HOH HOH A . O 6 HOH 59 4060 59 HOH HOH A . O 6 HOH 60 4061 60 HOH HOH A . O 6 HOH 61 4062 61 HOH HOH A . O 6 HOH 62 4063 62 HOH HOH A . O 6 HOH 63 4064 63 HOH HOH A . O 6 HOH 64 4065 64 HOH HOH A . O 6 HOH 65 4066 65 HOH HOH A . O 6 HOH 66 4067 66 HOH HOH A . O 6 HOH 67 4068 67 HOH HOH A . O 6 HOH 68 4069 68 HOH HOH A . O 6 HOH 69 4070 69 HOH HOH A . O 6 HOH 70 4071 70 HOH HOH A . O 6 HOH 71 4072 71 HOH HOH A . O 6 HOH 72 4073 72 HOH HOH A . O 6 HOH 73 4074 73 HOH HOH A . O 6 HOH 74 4075 74 HOH HOH A . O 6 HOH 75 4076 75 HOH HOH A . O 6 HOH 76 4077 76 HOH HOH A . O 6 HOH 77 4078 77 HOH HOH A . O 6 HOH 78 4079 78 HOH HOH A . O 6 HOH 79 4080 79 HOH HOH A . O 6 HOH 80 4081 80 HOH HOH A . O 6 HOH 81 4082 81 HOH HOH A . O 6 HOH 82 4083 82 HOH HOH A . O 6 HOH 83 4084 83 HOH HOH A . O 6 HOH 84 4085 84 HOH HOH A . O 6 HOH 85 4086 85 HOH HOH A . O 6 HOH 86 4087 86 HOH HOH A . O 6 HOH 87 4088 87 HOH HOH A . O 6 HOH 88 4089 88 HOH HOH A . O 6 HOH 89 4090 89 HOH HOH A . O 6 HOH 90 4091 90 HOH HOH A . O 6 HOH 91 4092 91 HOH HOH A . O 6 HOH 92 4093 92 HOH HOH A . O 6 HOH 93 4094 93 HOH HOH A . O 6 HOH 94 4095 94 HOH HOH A . O 6 HOH 95 4096 95 HOH HOH A . O 6 HOH 96 4097 96 HOH HOH A . O 6 HOH 97 4098 97 HOH HOH A . O 6 HOH 98 4099 98 HOH HOH A . O 6 HOH 99 4100 99 HOH HOH A . O 6 HOH 100 4101 100 HOH HOH A . O 6 HOH 101 4102 101 HOH HOH A . O 6 HOH 102 4103 102 HOH HOH A . O 6 HOH 103 4104 103 HOH HOH A . O 6 HOH 104 4105 104 HOH HOH A . O 6 HOH 105 4106 105 HOH HOH A . O 6 HOH 106 4107 106 HOH HOH A . O 6 HOH 107 4108 107 HOH HOH A . O 6 HOH 108 4109 108 HOH HOH A . O 6 HOH 109 4110 109 HOH HOH A . O 6 HOH 110 4111 110 HOH HOH A . O 6 HOH 111 4112 111 HOH HOH A . O 6 HOH 112 4113 112 HOH HOH A . O 6 HOH 113 4114 113 HOH HOH A . O 6 HOH 114 4115 114 HOH HOH A . O 6 HOH 115 4116 115 HOH HOH A . O 6 HOH 116 4117 116 HOH HOH A . O 6 HOH 117 4118 117 HOH HOH A . O 6 HOH 118 4119 118 HOH HOH A . O 6 HOH 119 4120 119 HOH HOH A . O 6 HOH 120 4121 120 HOH HOH A . O 6 HOH 121 4122 121 HOH HOH A . O 6 HOH 122 4123 122 HOH HOH A . O 6 HOH 123 4124 123 HOH HOH A . O 6 HOH 124 4125 124 HOH HOH A . O 6 HOH 125 4126 125 HOH HOH A . O 6 HOH 126 4127 126 HOH HOH A . O 6 HOH 127 4128 127 HOH HOH A . O 6 HOH 128 4129 128 HOH HOH A . O 6 HOH 129 4130 129 HOH HOH A . O 6 HOH 130 4131 130 HOH HOH A . O 6 HOH 131 4132 131 HOH HOH A . O 6 HOH 132 4133 132 HOH HOH A . O 6 HOH 133 4134 133 HOH HOH A . O 6 HOH 134 4135 134 HOH HOH A . O 6 HOH 135 4136 135 HOH HOH A . O 6 HOH 136 4137 136 HOH HOH A . O 6 HOH 137 4138 137 HOH HOH A . O 6 HOH 138 4139 138 HOH HOH A . O 6 HOH 139 4140 139 HOH HOH A . O 6 HOH 140 4141 140 HOH HOH A . O 6 HOH 141 4142 141 HOH HOH A . O 6 HOH 142 4143 142 HOH HOH A . O 6 HOH 143 4144 143 HOH HOH A . O 6 HOH 144 4145 144 HOH HOH A . O 6 HOH 145 4146 145 HOH HOH A . O 6 HOH 146 4147 146 HOH HOH A . O 6 HOH 147 4148 147 HOH HOH A . O 6 HOH 148 4149 148 HOH HOH A . O 6 HOH 149 4150 149 HOH HOH A . O 6 HOH 150 4151 150 HOH HOH A . O 6 HOH 151 4152 151 HOH HOH A . O 6 HOH 152 4153 152 HOH HOH A . O 6 HOH 153 4154 153 HOH HOH A . O 6 HOH 154 4155 154 HOH HOH A . O 6 HOH 155 4156 155 HOH HOH A . O 6 HOH 156 4157 156 HOH HOH A . O 6 HOH 157 4158 157 HOH HOH A . O 6 HOH 158 4159 158 HOH HOH A . O 6 HOH 159 4160 159 HOH HOH A . O 6 HOH 160 4161 160 HOH HOH A . O 6 HOH 161 4162 161 HOH HOH A . O 6 HOH 162 4163 162 HOH HOH A . O 6 HOH 163 4164 163 HOH HOH A . O 6 HOH 164 4165 164 HOH HOH A . O 6 HOH 165 4166 165 HOH HOH A . O 6 HOH 166 4167 166 HOH HOH A . O 6 HOH 167 4168 167 HOH HOH A . O 6 HOH 168 4169 168 HOH HOH A . O 6 HOH 169 4170 169 HOH HOH A . O 6 HOH 170 4171 170 HOH HOH A . O 6 HOH 171 4172 171 HOH HOH A . O 6 HOH 172 4173 172 HOH HOH A . O 6 HOH 173 4174 173 HOH HOH A . O 6 HOH 174 4175 174 HOH HOH A . O 6 HOH 175 4176 175 HOH HOH A . O 6 HOH 176 4177 176 HOH HOH A . O 6 HOH 177 4178 177 HOH HOH A . O 6 HOH 178 4179 178 HOH HOH A . O 6 HOH 179 4180 179 HOH HOH A . O 6 HOH 180 4181 180 HOH HOH A . O 6 HOH 181 4182 181 HOH HOH A . O 6 HOH 182 4183 182 HOH HOH A . O 6 HOH 183 4184 183 HOH HOH A . O 6 HOH 184 4185 184 HOH HOH A . O 6 HOH 185 4186 185 HOH HOH A . O 6 HOH 186 4187 186 HOH HOH A . O 6 HOH 187 4188 187 HOH HOH A . O 6 HOH 188 4189 188 HOH HOH A . O 6 HOH 189 4190 189 HOH HOH A . O 6 HOH 190 4191 190 HOH HOH A . O 6 HOH 191 4192 191 HOH HOH A . O 6 HOH 192 4193 192 HOH HOH A . O 6 HOH 193 4194 193 HOH HOH A . O 6 HOH 194 4195 194 HOH HOH A . O 6 HOH 195 4196 195 HOH HOH A . O 6 HOH 196 4197 196 HOH HOH A . O 6 HOH 197 4198 197 HOH HOH A . O 6 HOH 198 4199 198 HOH HOH A . O 6 HOH 199 4200 199 HOH HOH A . O 6 HOH 200 4201 200 HOH HOH A . O 6 HOH 201 4202 201 HOH HOH A . O 6 HOH 202 4203 202 HOH HOH A . O 6 HOH 203 4204 203 HOH HOH A . O 6 HOH 204 4205 204 HOH HOH A . O 6 HOH 205 4206 205 HOH HOH A . O 6 HOH 206 4207 206 HOH HOH A . O 6 HOH 207 4208 207 HOH HOH A . O 6 HOH 208 4209 208 HOH HOH A . O 6 HOH 209 4210 209 HOH HOH A . O 6 HOH 210 4211 210 HOH HOH A . O 6 HOH 211 4212 211 HOH HOH A . O 6 HOH 212 4213 212 HOH HOH A . O 6 HOH 213 4214 213 HOH HOH A . O 6 HOH 214 4215 214 HOH HOH A . O 6 HOH 215 4216 215 HOH HOH A . O 6 HOH 216 4217 216 HOH HOH A . O 6 HOH 217 4218 217 HOH HOH A . O 6 HOH 218 4219 218 HOH HOH A . O 6 HOH 219 4220 219 HOH HOH A . O 6 HOH 220 4221 220 HOH HOH A . O 6 HOH 221 4222 221 HOH HOH A . O 6 HOH 222 4223 222 HOH HOH A . O 6 HOH 223 4224 223 HOH HOH A . O 6 HOH 224 4225 224 HOH HOH A . O 6 HOH 225 4226 225 HOH HOH A . O 6 HOH 226 4227 226 HOH HOH A . O 6 HOH 227 4228 227 HOH HOH A . O 6 HOH 228 4229 228 HOH HOH A . O 6 HOH 229 4230 229 HOH HOH A . O 6 HOH 230 4231 230 HOH HOH A . O 6 HOH 231 4232 231 HOH HOH A . O 6 HOH 232 4233 232 HOH HOH A . O 6 HOH 233 4234 233 HOH HOH A . O 6 HOH 234 4235 234 HOH HOH A . O 6 HOH 235 4236 235 HOH HOH A . O 6 HOH 236 4237 236 HOH HOH A . O 6 HOH 237 4238 237 HOH HOH A . O 6 HOH 238 4239 238 HOH HOH A . O 6 HOH 239 4240 239 HOH HOH A . O 6 HOH 240 4241 240 HOH HOH A . O 6 HOH 241 4242 241 HOH HOH A . O 6 HOH 242 4243 242 HOH HOH A . O 6 HOH 243 4244 243 HOH HOH A . O 6 HOH 244 4245 244 HOH HOH A . O 6 HOH 245 4246 245 HOH HOH A . O 6 HOH 246 4247 246 HOH HOH A . O 6 HOH 247 4248 247 HOH HOH A . O 6 HOH 248 4249 248 HOH HOH A . O 6 HOH 249 4250 249 HOH HOH A . O 6 HOH 250 4251 250 HOH HOH A . O 6 HOH 251 4252 251 HOH HOH A . O 6 HOH 252 4253 252 HOH HOH A . O 6 HOH 253 4254 253 HOH HOH A . O 6 HOH 254 4255 254 HOH HOH A . O 6 HOH 255 4256 255 HOH HOH A . O 6 HOH 256 4257 256 HOH HOH A . O 6 HOH 257 4258 257 HOH HOH A . O 6 HOH 258 4259 258 HOH HOH A . O 6 HOH 259 4260 259 HOH HOH A . O 6 HOH 260 4261 260 HOH HOH A . O 6 HOH 261 4262 261 HOH HOH A . O 6 HOH 262 4263 262 HOH HOH A . O 6 HOH 263 4264 263 HOH HOH A . O 6 HOH 264 4265 264 HOH HOH A . O 6 HOH 265 4266 265 HOH HOH A . O 6 HOH 266 4267 266 HOH HOH A . O 6 HOH 267 4268 267 HOH HOH A . O 6 HOH 268 4269 268 HOH HOH A . O 6 HOH 269 4270 269 HOH HOH A . O 6 HOH 270 4271 270 HOH HOH A . O 6 HOH 271 4272 271 HOH HOH A . O 6 HOH 272 4273 272 HOH HOH A . O 6 HOH 273 4274 273 HOH HOH A . O 6 HOH 274 4275 274 HOH HOH A . O 6 HOH 275 4276 275 HOH HOH A . O 6 HOH 276 4277 276 HOH HOH A . O 6 HOH 277 4278 277 HOH HOH A . O 6 HOH 278 4279 278 HOH HOH A . O 6 HOH 279 4280 279 HOH HOH A . O 6 HOH 280 4281 280 HOH HOH A . O 6 HOH 281 4282 281 HOH HOH A . O 6 HOH 282 4283 282 HOH HOH A . O 6 HOH 283 4284 283 HOH HOH A . O 6 HOH 284 4285 284 HOH HOH A . O 6 HOH 285 4286 285 HOH HOH A . O 6 HOH 286 4287 286 HOH HOH A . O 6 HOH 287 4288 287 HOH HOH A . O 6 HOH 288 4289 288 HOH HOH A . O 6 HOH 289 4290 289 HOH HOH A . O 6 HOH 290 4291 290 HOH HOH A . O 6 HOH 291 4292 291 HOH HOH A . O 6 HOH 292 4293 292 HOH HOH A . O 6 HOH 293 4294 293 HOH HOH A . O 6 HOH 294 4295 294 HOH HOH A . O 6 HOH 295 4296 295 HOH HOH A . O 6 HOH 296 4297 296 HOH HOH A . O 6 HOH 297 4298 297 HOH HOH A . O 6 HOH 298 4299 298 HOH HOH A . O 6 HOH 299 4300 299 HOH HOH A . O 6 HOH 300 4301 300 HOH HOH A . O 6 HOH 301 4302 301 HOH HOH A . O 6 HOH 302 4303 302 HOH HOH A . O 6 HOH 303 4304 303 HOH HOH A . O 6 HOH 304 4305 304 HOH HOH A . O 6 HOH 305 4306 305 HOH HOH A . O 6 HOH 306 4307 306 HOH HOH A . O 6 HOH 307 4308 307 HOH HOH A . O 6 HOH 308 4309 308 HOH HOH A . O 6 HOH 309 4310 309 HOH HOH A . O 6 HOH 310 4311 310 HOH HOH A . O 6 HOH 311 4312 311 HOH HOH A . O 6 HOH 312 4313 312 HOH HOH A . O 6 HOH 313 4314 313 HOH HOH A . O 6 HOH 314 4315 314 HOH HOH A . O 6 HOH 315 4316 315 HOH HOH A . O 6 HOH 316 4317 316 HOH HOH A . O 6 HOH 317 4318 317 HOH HOH A . O 6 HOH 318 4319 318 HOH HOH A . O 6 HOH 319 4320 319 HOH HOH A . O 6 HOH 320 4321 320 HOH HOH A . O 6 HOH 321 4322 321 HOH HOH A . O 6 HOH 322 4323 322 HOH HOH A . O 6 HOH 323 4324 323 HOH HOH A . O 6 HOH 324 4325 324 HOH HOH A . O 6 HOH 325 4326 325 HOH HOH A . O 6 HOH 326 4327 326 HOH HOH A . O 6 HOH 327 4328 327 HOH HOH A . O 6 HOH 328 4329 328 HOH HOH A . O 6 HOH 329 4330 329 HOH HOH A . O 6 HOH 330 4331 330 HOH HOH A . O 6 HOH 331 4332 331 HOH HOH A . O 6 HOH 332 4333 332 HOH HOH A . O 6 HOH 333 4334 333 HOH HOH A . O 6 HOH 334 4335 334 HOH HOH A . O 6 HOH 335 4336 335 HOH HOH A . O 6 HOH 336 4337 336 HOH HOH A . O 6 HOH 337 4338 337 HOH HOH A . O 6 HOH 338 4339 338 HOH HOH A . O 6 HOH 339 4340 339 HOH HOH A . O 6 HOH 340 4341 340 HOH HOH A . O 6 HOH 341 4342 341 HOH HOH A . O 6 HOH 342 4343 342 HOH HOH A . O 6 HOH 343 4344 343 HOH HOH A . O 6 HOH 344 4345 344 HOH HOH A . O 6 HOH 345 4346 345 HOH HOH A . O 6 HOH 346 4347 346 HOH HOH A . O 6 HOH 347 4348 347 HOH HOH A . O 6 HOH 348 4349 348 HOH HOH A . O 6 HOH 349 4350 349 HOH HOH A . O 6 HOH 350 4351 350 HOH HOH A . O 6 HOH 351 4352 351 HOH HOH A . O 6 HOH 352 4353 352 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 393 A ASN 393 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 741 A ASN 741 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2009-02-24 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-10-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' 3 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _pdbx_phasing_MR.entry_id 3CTT _pdbx_phasing_MR.method_rotation ? _pdbx_phasing_MR.method_translation ? _pdbx_phasing_MR.model_details 'Phaser MODE: MR_AUTO' _pdbx_phasing_MR.R_factor ? _pdbx_phasing_MR.R_rigid_body ? _pdbx_phasing_MR.correlation_coeff_Fo_to_Fc ? _pdbx_phasing_MR.correlation_coeff_Io_to_Ic ? _pdbx_phasing_MR.d_res_high_rotation 2.500 _pdbx_phasing_MR.d_res_low_rotation 15.660 _pdbx_phasing_MR.d_res_high_translation 2.500 _pdbx_phasing_MR.d_res_low_translation 15.660 _pdbx_phasing_MR.packing ? _pdbx_phasing_MR.reflns_percent_rotation ? _pdbx_phasing_MR.reflns_percent_translation ? _pdbx_phasing_MR.sigma_F_rotation ? _pdbx_phasing_MR.sigma_F_translation ? _pdbx_phasing_MR.sigma_I_rotation ? _pdbx_phasing_MR.sigma_I_translation ? # _phasing.method MR # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal DENZO . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data reduction' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 1 SCALEPACK . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data scaling' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 2 PHASER . ? other 'R. J. Read' cimr-phaser@lists.cam.ac.uk phasing http://www-structmed.cimr.cam.ac.uk/phaser/ ? ? 3 REFMAC . ? program 'Murshudov, G.N.' ccp4@dl.ac.uk refinement http://www.ccp4.ac.uk/main.html Fortran_77 ? 4 PDB_EXTRACT 3.005 'September 10, 2007' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 5 HKL-2000 . ? ? ? ? 'data collection' ? ? ? 6 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OD2 A ASP 772 ? ? OG1 A THR 775 ? ? 2.15 2 1 O A HOH 4097 ? ? O A HOH 4350 ? ? 2.16 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 34 ? ? -157.73 89.27 2 1 SER A 40 ? ? 78.46 -14.36 3 1 HIS A 50 ? ? 155.95 158.06 4 1 SER A 51 ? ? 91.18 -136.42 5 1 SER A 80 ? ? -56.52 99.75 6 1 LEU A 151 ? ? -97.81 -61.02 7 1 PHE A 161 ? ? -151.00 80.89 8 1 LEU A 180 ? ? 65.30 146.58 9 1 GLN A 186 ? ? 75.15 -46.57 10 1 ASP A 191 ? ? -43.29 92.32 11 1 TRP A 194 ? ? -55.11 107.42 12 1 PRO A 206 ? ? -65.83 96.08 13 1 LEU A 213 ? ? -118.68 -148.59 14 1 GLU A 300 ? ? 71.81 69.58 15 1 TYR A 321 ? ? -170.40 100.17 16 1 VAL A 342 ? ? -106.01 -61.66 17 1 LYS A 377 ? ? -154.95 68.34 18 1 VAL A 405 ? ? -130.41 -148.15 19 1 ASP A 474 ? ? 77.18 -23.61 20 1 THR A 481 ? ? -150.88 -158.02 21 1 ASN A 518 ? ? 57.51 13.14 22 1 SER A 521 ? ? 58.70 -142.62 23 1 ASN A 543 ? ? -74.59 -169.13 24 1 ILE A 565 ? ? -118.30 71.75 25 1 CYS A 573 ? ? 80.78 -11.20 26 1 LEU A 577 ? ? 88.61 157.36 27 1 VAL A 651 ? ? -107.17 -67.39 28 1 GLU A 774 ? ? -154.05 -20.44 29 1 ASP A 777 ? ? 83.93 8.85 30 1 VAL A 783 ? ? -117.57 79.05 31 1 GLN A 793 ? ? -10.17 126.39 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 1 ? A SER 1 2 1 Y 1 A ALA 2 ? A ALA 2 3 1 Y 1 A GLU 3 ? A GLU 3 4 1 Y 1 A CYS 4 ? A CYS 4 5 1 Y 1 A PRO 5 ? A PRO 5 6 1 Y 1 A VAL 6 ? A VAL 6 7 1 Y 1 A GLN 837 ? A GLN 837 8 1 Y 1 A THR 838 ? A THR 838 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'SULFATE ION' SO4 4 CASUARINE 3CU 5 GLYCEROL GOL 6 water HOH #