data_2WXD # _entry.id 2WXD # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2WXD PDBE EBI-41679 WWPDB D_1290041679 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 1DWH unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL. STRUCTURE AFTER IRRADIATION WITH 27. 2*10E15 PHOTONS/MM2' PDB 1DWJ unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL. REFINED STRUCTURE AFTER A RADIATION DOSE OF 54*10E15 PHOTONS/MM2' PDB 1E70 unspecified '2-F-GLUCOSYLATED MYROSINASE FROM SINAPIS ALBA' PDB 1E72 unspecified 'MYROSINASE FROM SINAPIS ALBA WITH BOUND GLUCO-HYDROXIMOLACTAM AND SULFATE OR ASCORBATE' PDB 1E73 unspecified '2-F-GLUCOSYLATED MYROSINASE FROM SINAPIS ALBA WITH BOUND L-ASCORBATE' PDB 1DWI unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL. STRUCTURE AFTER IRRADIATION WITH 54. 0*10E15 PHOTONS/MM2' PDB 1W9B unspecified 'S. ALBA MYROSINASE IN COMPLEX WITH CARBA- GLUCOTROPAEOLIN' PDB 1E71 unspecified 'MYROSINASE FROM SINAPIS ALBA WITH BOUND ASCORBATE' PDB 1DWG unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL: STRUCTURE AFTER IRRADIATION WITH 18. 2*10E15 PHOTONS/MM2.' PDB 1E6S unspecified 'MYROSINASE FROM SINAPIS ALBA WITH BOUND GLUCO-HYDROXIMOLACTAM AND SULFATE' PDB 1DWA unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL. STRUCTURE PRIOR TO IRRADIATION' PDB 1DWF unspecified 'STUDY ON RADIATION DAMAGE ON A CRYOCOOLED CRYSTAL. STRUCTURE AFTER IRRADIATION WITH 9. 1*10E15 PHOTONS/MM2' PDB 1W9D unspecified 'S. ALBA MYROSINASE IN COMPLEX WITH S-ETHYL PHENYLACETOTHIOHYDROXIMATE-O-SULFATE' PDB 1MYR unspecified 'MYROSINASE FROM SINAPIS ALBA' PDB 1E6Q unspecified 'MYROSINASE FROM SINAPIS ALBA WITH THE BOUND TRANSITION STATE ANALOGUE GLUCO-TETRAZOLE' PDB 1E4M unspecified 'MYROSINASE FROM SINAPIS ALBA' PDB 1E6X unspecified 'MYROSINASE FROM SINAPIS ALBA WITH A BOUND TRANSITION STATE ANALOGUE,D-GLUCONO-1,5- LACTONE' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2WXD _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2009-11-09 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Besle, A.' 1 'Burmeister, W.P.' 2 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'A Micromolar O-Sulfated Thiohydroximate Inhibitor Bound to Plant Myrosinase' 'Acta Crystallogr.,Sect.F' 66 152 ? 2010 ? DK 1744-3091 ? ? 20124710 10.1107/S1744309109052865 1 'A Simple O-Sulfated Thiohydroximate Molecule to be the First Micromolar Range Myrosinase Inhibitor' 'Tetrahedron Letters' 50 3302 ? 2009 TELEAY UK 0040-4039 0024 ? ? 10.1016/J.TETLET.2009.02.072 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Besle, A.' 1 primary 'Brazzolotto, X.' 2 primary 'Tatibouet, A.' 3 primary 'Cerniauskaite, D.' 4 primary 'Gallienne, E.' 5 primary 'Rollin, P.' 6 primary 'Burmeister, W.P.' 7 1 'Cerniauskaite, D.' 8 1 'Gallienne, E.' 9 1 'Karciauskaite, H.' 10 1 'Farinha, A.S.F.' 11 1 'Rousseau, J.' 12 1 'Armand, S.' 13 1 'Tatibouet, A.' 14 1 'Sackus, A.' 15 1 'Rollin, P.' 16 # _cell.entry_id 2WXD _cell.length_a 136.245 _cell.length_b 137.567 _cell.length_c 80.723 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 2WXD _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 20 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat MYROSINASE 57078.289 1 3.2.3.1 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 16 ? ? ? ? 3 non-polymer man ALPHA-L-FUCOSE 164.156 2 ? ? ? ? 4 non-polymer man BETA-D-MANNOSE 180.156 2 ? ? ? ? 5 non-polymer man BETA-D-XYLOPYRANOSE 150.130 2 ? ? ? ? 6 non-polymer man ALPHA-D-MANNOSE 180.156 2 ? ? ? ? 7 non-polymer syn '2-(DIMETHYLAMINO)ETHYL (1Z)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE' 318.412 1 ? ? ? ? 8 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 9 non-polymer syn 'SULFATE ION' 96.063 7 ? ? ? ? 10 non-polymer syn GLYCEROL 92.094 4 ? ? ? ? 11 water nat water 18.015 764 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'SINIGRINASE, THIOGLUCOSIDASE' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;DEEITCQENLPFTCGNTDALNSSSFSSDFIFGVASSAYQIEGTIGRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQ KDIDVLDELNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTLQDEYEGFLDPQI IDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSPTVDPSCYAGNSSTEPYIVAHHQLLAHAKVVDL YRKNYTHQGGKIGPTMITRWFLPYNDTDRHSIAATERMKEFFLGWFMGPLTNGTYPQIMIDTVGERLPSFSPEESNLVKG SYDFLGLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYINASGHYIGPLFEKDKADSTDNIYYYPKGIYSVMDYFKNKY YNPLIYVTENGISTPGDENRNQSMLDYTRIDYLCSHLCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGLSYIDW NNVTDRDLKKSGQWYQSFISP ; _entity_poly.pdbx_seq_one_letter_code_can ;DEEITCQENLPFTCGNTDALNSSSFSSDFIFGVASSAYQIEGTIGRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQ KDIDVLDELNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTLQDEYEGFLDPQI IDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSPTVDPSCYAGNSSTEPYIVAHHQLLAHAKVVDL YRKNYTHQGGKIGPTMITRWFLPYNDTDRHSIAATERMKEFFLGWFMGPLTNGTYPQIMIDTVGERLPSFSPEESNLVKG SYDFLGLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYINASGHYIGPLFEKDKADSTDNIYYYPKGIYSVMDYFKNKY YNPLIYVTENGISTPGDENRNQSMLDYTRIDYLCSHLCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGLSYIDW NNVTDRDLKKSGQWYQSFISP ; _entity_poly.pdbx_strand_id M _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 GLU n 1 3 GLU n 1 4 ILE n 1 5 THR n 1 6 CYS n 1 7 GLN n 1 8 GLU n 1 9 ASN n 1 10 LEU n 1 11 PRO n 1 12 PHE n 1 13 THR n 1 14 CYS n 1 15 GLY n 1 16 ASN n 1 17 THR n 1 18 ASP n 1 19 ALA n 1 20 LEU n 1 21 ASN n 1 22 SER n 1 23 SER n 1 24 SER n 1 25 PHE n 1 26 SER n 1 27 SER n 1 28 ASP n 1 29 PHE n 1 30 ILE n 1 31 PHE n 1 32 GLY n 1 33 VAL n 1 34 ALA n 1 35 SER n 1 36 SER n 1 37 ALA n 1 38 TYR n 1 39 GLN n 1 40 ILE n 1 41 GLU n 1 42 GLY n 1 43 THR n 1 44 ILE n 1 45 GLY n 1 46 ARG n 1 47 GLY n 1 48 LEU n 1 49 ASN n 1 50 ILE n 1 51 TRP n 1 52 ASP n 1 53 GLY n 1 54 PHE n 1 55 THR n 1 56 HIS n 1 57 ARG n 1 58 TYR n 1 59 PRO n 1 60 ASN n 1 61 LYS n 1 62 SER n 1 63 GLY n 1 64 PRO n 1 65 ASP n 1 66 HIS n 1 67 GLY n 1 68 ASN n 1 69 GLY n 1 70 ASP n 1 71 THR n 1 72 THR n 1 73 CYS n 1 74 ASP n 1 75 SER n 1 76 PHE n 1 77 SER n 1 78 TYR n 1 79 TRP n 1 80 GLN n 1 81 LYS n 1 82 ASP n 1 83 ILE n 1 84 ASP n 1 85 VAL n 1 86 LEU n 1 87 ASP n 1 88 GLU n 1 89 LEU n 1 90 ASN n 1 91 ALA n 1 92 THR n 1 93 GLY n 1 94 TYR n 1 95 ARG n 1 96 PHE n 1 97 SER n 1 98 ILE n 1 99 ALA n 1 100 TRP n 1 101 SER n 1 102 ARG n 1 103 ILE n 1 104 ILE n 1 105 PRO n 1 106 ARG n 1 107 GLY n 1 108 LYS n 1 109 ARG n 1 110 SER n 1 111 ARG n 1 112 GLY n 1 113 VAL n 1 114 ASN n 1 115 GLU n 1 116 LYS n 1 117 GLY n 1 118 ILE n 1 119 ASP n 1 120 TYR n 1 121 TYR n 1 122 HIS n 1 123 GLY n 1 124 LEU n 1 125 ILE n 1 126 SER n 1 127 GLY n 1 128 LEU n 1 129 ILE n 1 130 LYS n 1 131 LYS n 1 132 GLY n 1 133 ILE n 1 134 THR n 1 135 PRO n 1 136 PHE n 1 137 VAL n 1 138 THR n 1 139 LEU n 1 140 PHE n 1 141 HIS n 1 142 TRP n 1 143 ASP n 1 144 LEU n 1 145 PRO n 1 146 GLN n 1 147 THR n 1 148 LEU n 1 149 GLN n 1 150 ASP n 1 151 GLU n 1 152 TYR n 1 153 GLU n 1 154 GLY n 1 155 PHE n 1 156 LEU n 1 157 ASP n 1 158 PRO n 1 159 GLN n 1 160 ILE n 1 161 ILE n 1 162 ASP n 1 163 ASP n 1 164 PHE n 1 165 LYS n 1 166 ASP n 1 167 TYR n 1 168 ALA n 1 169 ASP n 1 170 LEU n 1 171 CYS n 1 172 PHE n 1 173 GLU n 1 174 GLU n 1 175 PHE n 1 176 GLY n 1 177 ASP n 1 178 SER n 1 179 VAL n 1 180 LYS n 1 181 TYR n 1 182 TRP n 1 183 LEU n 1 184 THR n 1 185 ILE n 1 186 ASN n 1 187 GLN n 1 188 LEU n 1 189 TYR n 1 190 SER n 1 191 VAL n 1 192 PRO n 1 193 THR n 1 194 ARG n 1 195 GLY n 1 196 TYR n 1 197 GLY n 1 198 SER n 1 199 ALA n 1 200 LEU n 1 201 ASP n 1 202 ALA n 1 203 PRO n 1 204 GLY n 1 205 ARG n 1 206 CYS n 1 207 SER n 1 208 PRO n 1 209 THR n 1 210 VAL n 1 211 ASP n 1 212 PRO n 1 213 SER n 1 214 CYS n 1 215 TYR n 1 216 ALA n 1 217 GLY n 1 218 ASN n 1 219 SER n 1 220 SER n 1 221 THR n 1 222 GLU n 1 223 PRO n 1 224 TYR n 1 225 ILE n 1 226 VAL n 1 227 ALA n 1 228 HIS n 1 229 HIS n 1 230 GLN n 1 231 LEU n 1 232 LEU n 1 233 ALA n 1 234 HIS n 1 235 ALA n 1 236 LYS n 1 237 VAL n 1 238 VAL n 1 239 ASP n 1 240 LEU n 1 241 TYR n 1 242 ARG n 1 243 LYS n 1 244 ASN n 1 245 TYR n 1 246 THR n 1 247 HIS n 1 248 GLN n 1 249 GLY n 1 250 GLY n 1 251 LYS n 1 252 ILE n 1 253 GLY n 1 254 PRO n 1 255 THR n 1 256 MET n 1 257 ILE n 1 258 THR n 1 259 ARG n 1 260 TRP n 1 261 PHE n 1 262 LEU n 1 263 PRO n 1 264 TYR n 1 265 ASN n 1 266 ASP n 1 267 THR n 1 268 ASP n 1 269 ARG n 1 270 HIS n 1 271 SER n 1 272 ILE n 1 273 ALA n 1 274 ALA n 1 275 THR n 1 276 GLU n 1 277 ARG n 1 278 MET n 1 279 LYS n 1 280 GLU n 1 281 PHE n 1 282 PHE n 1 283 LEU n 1 284 GLY n 1 285 TRP n 1 286 PHE n 1 287 MET n 1 288 GLY n 1 289 PRO n 1 290 LEU n 1 291 THR n 1 292 ASN n 1 293 GLY n 1 294 THR n 1 295 TYR n 1 296 PRO n 1 297 GLN n 1 298 ILE n 1 299 MET n 1 300 ILE n 1 301 ASP n 1 302 THR n 1 303 VAL n 1 304 GLY n 1 305 GLU n 1 306 ARG n 1 307 LEU n 1 308 PRO n 1 309 SER n 1 310 PHE n 1 311 SER n 1 312 PRO n 1 313 GLU n 1 314 GLU n 1 315 SER n 1 316 ASN n 1 317 LEU n 1 318 VAL n 1 319 LYS n 1 320 GLY n 1 321 SER n 1 322 TYR n 1 323 ASP n 1 324 PHE n 1 325 LEU n 1 326 GLY n 1 327 LEU n 1 328 ASN n 1 329 TYR n 1 330 TYR n 1 331 PHE n 1 332 THR n 1 333 GLN n 1 334 TYR n 1 335 ALA n 1 336 GLN n 1 337 PRO n 1 338 SER n 1 339 PRO n 1 340 ASN n 1 341 PRO n 1 342 VAL n 1 343 ASN n 1 344 SER n 1 345 THR n 1 346 ASN n 1 347 HIS n 1 348 THR n 1 349 ALA n 1 350 MET n 1 351 MET n 1 352 ASP n 1 353 ALA n 1 354 GLY n 1 355 ALA n 1 356 LYS n 1 357 LEU n 1 358 THR n 1 359 TYR n 1 360 ILE n 1 361 ASN n 1 362 ALA n 1 363 SER n 1 364 GLY n 1 365 HIS n 1 366 TYR n 1 367 ILE n 1 368 GLY n 1 369 PRO n 1 370 LEU n 1 371 PHE n 1 372 GLU n 1 373 LYS n 1 374 ASP n 1 375 LYS n 1 376 ALA n 1 377 ASP n 1 378 SER n 1 379 THR n 1 380 ASP n 1 381 ASN n 1 382 ILE n 1 383 TYR n 1 384 TYR n 1 385 TYR n 1 386 PRO n 1 387 LYS n 1 388 GLY n 1 389 ILE n 1 390 TYR n 1 391 SER n 1 392 VAL n 1 393 MET n 1 394 ASP n 1 395 TYR n 1 396 PHE n 1 397 LYS n 1 398 ASN n 1 399 LYS n 1 400 TYR n 1 401 TYR n 1 402 ASN n 1 403 PRO n 1 404 LEU n 1 405 ILE n 1 406 TYR n 1 407 VAL n 1 408 THR n 1 409 GLU n 1 410 ASN n 1 411 GLY n 1 412 ILE n 1 413 SER n 1 414 THR n 1 415 PRO n 1 416 GLY n 1 417 ASP n 1 418 GLU n 1 419 ASN n 1 420 ARG n 1 421 ASN n 1 422 GLN n 1 423 SER n 1 424 MET n 1 425 LEU n 1 426 ASP n 1 427 TYR n 1 428 THR n 1 429 ARG n 1 430 ILE n 1 431 ASP n 1 432 TYR n 1 433 LEU n 1 434 CYS n 1 435 SER n 1 436 HIS n 1 437 LEU n 1 438 CYS n 1 439 PHE n 1 440 LEU n 1 441 ASN n 1 442 LYS n 1 443 VAL n 1 444 ILE n 1 445 LYS n 1 446 GLU n 1 447 LYS n 1 448 ASP n 1 449 VAL n 1 450 ASN n 1 451 VAL n 1 452 LYS n 1 453 GLY n 1 454 TYR n 1 455 LEU n 1 456 ALA n 1 457 TRP n 1 458 ALA n 1 459 LEU n 1 460 GLY n 1 461 ASP n 1 462 ASN n 1 463 TYR n 1 464 GLU n 1 465 PHE n 1 466 ASN n 1 467 LYS n 1 468 GLY n 1 469 PHE n 1 470 THR n 1 471 VAL n 1 472 ARG n 1 473 PHE n 1 474 GLY n 1 475 LEU n 1 476 SER n 1 477 TYR n 1 478 ILE n 1 479 ASP n 1 480 TRP n 1 481 ASN n 1 482 ASN n 1 483 VAL n 1 484 THR n 1 485 ASP n 1 486 ARG n 1 487 ASP n 1 488 LEU n 1 489 LYS n 1 490 LYS n 1 491 SER n 1 492 GLY n 1 493 GLN n 1 494 TRP n 1 495 TYR n 1 496 GLN n 1 497 SER n 1 498 PHE n 1 499 ILE n 1 500 SER n 1 501 PRO n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'WHITE MUSTARD' _entity_src_nat.pdbx_organism_scientific 'SINAPIS ALBA' _entity_src_nat.pdbx_ncbi_taxonomy_id 3728 _entity_src_nat.genus ? _entity_src_nat.species ? _entity_src_nat.strain EMERGO _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MYRA_SINAL _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession P29736 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2WXD _struct_ref_seq.pdbx_strand_id M _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 501 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P29736 _struct_ref_seq.db_align_beg 1 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 501 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 501 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 E18 non-polymer . '2-(DIMETHYLAMINO)ETHYL (1Z)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE' ? 'C12 H18 N2 O4 S2' 318.412 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 XYP D-saccharide . BETA-D-XYLOPYRANOSE ? 'C5 H10 O5' 150.130 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2WXD _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.56 _exptl_crystal.density_percent_sol 43 _exptl_crystal.description 'ISOMORPHOUS TO 1E4M' # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details 'TRIS-HCL PH 8, 68 % SAT AMMONIUM SULFATE; PROTEIN IN HEPES PH 6.5, 150 MM NACL, 0.02 MM ZNSO4; HANGING DROPS 2 AND 2 UL' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC CCD' _diffrn_detector.pdbx_collection_date 2008-02-18 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'DIAMOND (111)' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.933 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID14-2' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID14-2 _diffrn_source.pdbx_wavelength 0.933 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 2WXD _reflns.observed_criterion_sigma_I 0.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 80.85 _reflns.d_resolution_high 1.60 _reflns.number_obs 99631 _reflns.number_all ? _reflns.percent_possible_obs 99.7 _reflns.pdbx_Rmerge_I_obs 0.08 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 5.90 _reflns.B_iso_Wilson_estimate 15.4 _reflns.pdbx_redundancy 4.63 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 1.60 _reflns_shell.d_res_low 1.69 _reflns_shell.percent_possible_all 98.4 _reflns_shell.Rmerge_I_obs 0.38 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 1.71 _reflns_shell.pdbx_redundancy 3.87 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 2WXD _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 94531 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F . _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 68.78 _refine.ls_d_res_high 1.60 _refine.ls_percent_reflns_obs 99.84 _refine.ls_R_factor_obs 0.14368 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.14257 _refine.ls_R_factor_R_free 0.16408 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 5075 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.969 _refine.correlation_coeff_Fo_to_Fc_free 0.964 _refine.B_iso_mean 12.436 _refine.aniso_B[1][1] 0.00 _refine.aniso_B[2][2] 0.00 _refine.aniso_B[3][3] 0.00 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY' _refine.pdbx_starting_model 'PDB ENTRY 1E4M' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.062 _refine.pdbx_overall_ESU_R_Free 0.063 _refine.overall_SU_ML 0.036 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 1.004 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4007 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 386 _refine_hist.number_atoms_solvent 764 _refine_hist.number_atoms_total 5157 _refine_hist.d_res_high 1.60 _refine_hist.d_res_low 68.78 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.030 0.022 ? 4588 'X-RAY DIFFRACTION' ? r_bond_other_d 0.001 0.020 ? 3044 'X-RAY DIFFRACTION' ? r_angle_refined_deg 2.574 2.025 ? 6247 'X-RAY DIFFRACTION' ? r_angle_other_deg 1.662 3.000 ? 7338 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.264 5.000 ? 502 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 33.636 24.131 ? 213 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 11.154 15.000 ? 665 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 13.544 15.000 ? 19 'X-RAY DIFFRACTION' ? r_chiral_restr 0.174 0.200 ? 698 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.015 0.021 ? 4813 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.001 0.020 ? 934 'X-RAY DIFFRACTION' ? r_nbd_refined 0.374 0.200 ? 1077 'X-RAY DIFFRACTION' ? r_nbd_other 0.202 0.200 ? 3257 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.198 0.200 ? 2265 'X-RAY DIFFRACTION' ? r_nbtor_other 0.097 0.200 ? 2188 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.205 0.200 ? 615 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other 0.060 0.200 ? 2 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other 0.100 0.200 ? 1 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.242 0.200 ? 22 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other 0.289 0.200 ? 57 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.320 0.200 ? 55 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 1.516 1.500 ? 2504 'X-RAY DIFFRACTION' ? r_mcbond_other 0.539 1.500 ? 1016 'X-RAY DIFFRACTION' ? r_mcangle_it 2.533 2.000 ? 4077 'X-RAY DIFFRACTION' ? r_mcangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_it 5.507 3.000 ? 2084 'X-RAY DIFFRACTION' ? r_scbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_it 6.503 4.500 ? 2169 'X-RAY DIFFRACTION' ? r_scangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 1.600 _refine_ls_shell.d_res_low 1.642 _refine_ls_shell.number_reflns_R_work 6894 _refine_ls_shell.R_factor_R_work 0.223 _refine_ls_shell.percent_reflns_obs 99.13 _refine_ls_shell.R_factor_R_free 0.263 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 359 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 2WXD _struct.title 'A MICROMOLAR O-SULFATED THIOHYDROXIMATE INHIBITOR BOUND TO PLANT MYROSINASE' _struct.pdbx_descriptor 'MYROSINASE (E.C.3.2.3.1)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2WXD _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'VACUOLE, HYDROLASE, THIOHYDROXIMATE, GLUCOSINOLATE, FAMILY 1 GLYCOSYL HYDROLASE, GLYCOSIDASE, GLYCOPROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 3 ? J N N 2 ? K N N 4 ? L N N 5 ? M N N 2 ? N N N 3 ? O N N 2 ? P N N 4 ? Q N N 5 ? R N N 6 ? S N N 6 ? T N N 2 ? U N N 2 ? V N N 2 ? W N N 2 ? X N N 2 ? Y N N 2 ? Z N N 7 ? AA N N 8 ? BA N N 9 ? CA N N 9 ? DA N N 9 ? EA N N 9 ? FA N N 9 ? GA N N 9 ? HA N N 9 ? IA N N 10 ? JA N N 10 ? KA N N 10 ? LA N N 10 ? MA N N 11 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 21 ? PHE A 25 ? ASN M 21 PHE M 25 5 ? 5 HELX_P HELX_P2 2 SER A 36 ? GLU A 41 ? SER M 36 GLU M 41 1 ? 6 HELX_P HELX_P3 3 ASN A 49 ? TYR A 58 ? ASN M 49 TYR M 58 1 ? 10 HELX_P HELX_P4 4 TYR A 58 ? GLY A 63 ? TYR M 58 GLY M 63 1 ? 6 HELX_P HELX_P5 5 ASP A 74 ? ASN A 90 ? ASP M 74 ASN M 90 1 ? 17 HELX_P HELX_P6 6 ALA A 99 ? ILE A 104 ? ALA M 99 ILE M 104 1 ? 6 HELX_P HELX_P7 7 LYS A 108 ? GLY A 112 ? LYS M 108 GLY M 112 5 ? 5 HELX_P HELX_P8 8 ASN A 114 ? LYS A 131 ? ASN M 114 LYS M 131 1 ? 18 HELX_P HELX_P9 9 PRO A 145 ? GLU A 153 ? PRO M 145 GLU M 153 1 ? 9 HELX_P HELX_P10 10 GLY A 154 ? PRO A 158 ? GLY M 154 PRO M 158 5 ? 5 HELX_P HELX_P11 11 GLN A 159 ? GLY A 176 ? GLN M 159 GLY M 176 1 ? 18 HELX_P HELX_P12 12 TYR A 189 ? GLY A 197 ? TYR M 189 GLY M 197 1 ? 9 HELX_P HELX_P13 13 THR A 221 ? TYR A 245 ? THR M 221 TYR M 245 1 ? 25 HELX_P HELX_P14 14 THR A 246 ? GLY A 249 ? THR M 246 GLY M 249 5 ? 4 HELX_P HELX_P15 15 ASP A 268 ? LEU A 283 ? ASP M 268 LEU M 283 1 ? 16 HELX_P HELX_P16 16 LEU A 283 ? GLY A 293 ? LEU M 283 GLY M 293 1 ? 11 HELX_P HELX_P17 17 PRO A 296 ? GLY A 304 ? PRO M 296 GLY M 304 1 ? 9 HELX_P HELX_P18 18 GLU A 305 ? LEU A 307 ? GLU M 305 LEU M 307 5 ? 3 HELX_P HELX_P19 19 SER A 311 ? LYS A 319 ? SER M 311 LYS M 319 1 ? 9 HELX_P HELX_P20 20 THR A 348 ? ALA A 353 ? THR M 348 ALA M 353 5 ? 6 HELX_P HELX_P21 21 ASP A 377 ? ASN A 381 ? ASP M 377 ASN M 381 5 ? 5 HELX_P HELX_P22 22 PRO A 386 ? TYR A 400 ? PRO M 386 TYR M 400 1 ? 15 HELX_P HELX_P23 23 ASN A 419 ? LEU A 425 ? ASN M 419 LEU M 425 1 ? 7 HELX_P HELX_P24 24 ASP A 426 ? ASP A 448 ? ASP M 426 ASP M 448 1 ? 23 HELX_P HELX_P25 25 LYS A 489 ? SER A 500 ? LYS M 489 SER M 500 1 ? 12 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 6 SG ? ? ? 1_555 A CYS 438 SG ? ? M CYS 6 M CYS 438 1_555 ? ? ? ? ? ? ? 2.464 ? disulf2 disulf ? ? A CYS 14 SG ? ? ? 1_555 A CYS 434 SG ? ? M CYS 14 M CYS 434 1_555 ? ? ? ? ? ? ? 2.264 ? disulf3 disulf ? ? A CYS 206 SG ? ? ? 1_555 A CYS 214 SG ? ? M CYS 206 M CYS 214 1_555 ? ? ? ? ? ? ? 2.100 ? covale1 covale ? ? A ASN 21 ND2 ? ? ? 1_555 B NAG . C1 ? ? M ASN 21 M NAG 901 1_555 ? ? ? ? ? ? ? 1.624 ? covale2 covale ? ? A ASN 60 ND2 ? ? ? 1_555 T NAG . C1 ? ? M ASN 60 M NAG 961 1_555 ? ? ? ? ? ? ? 1.653 ? covale3 covale ? ? A ASN 90 ND2 ? ? ? 1_555 C NAG . C1 ? ? M ASN 90 M NAG 911 1_555 ? ? ? ? ? ? ? 1.600 ? covale4 covale ? ? A ASN 218 ND2 ? ? ? 1_555 E NAG . C1 ? ? M ASN 218 M NAG 921 1_555 ? ? ? ? ? ? ? 1.581 ? covale5 covale ? ? A ASN 244 ND2 ? ? ? 1_555 G NAG . C1 ? ? M ASN 244 M NAG 931 1_555 ? ? ? ? ? ? ? 1.782 ? covale6 covale ? ? A ASN 265 ND2 ? ? ? 1_555 H NAG . C1 ? ? M ASN 265 M NAG 941 1_555 ? ? ? ? ? ? ? 1.497 ? covale7 covale ? ? A ASN 292 ND2 ? ? ? 1_555 M NAG . C1 ? ? M ASN 292 M NAG 951 1_555 ? ? ? ? ? ? ? 1.578 ? covale8 covale ? ? A ASN 346 ND2 ? ? ? 1_555 V NAG . C1 ? ? M ASN 346 M NAG 971 1_555 ? ? ? ? ? ? ? 1.787 ? covale9 covale ? ? A ASN 361 ND2 ? ? ? 1_555 W NAG . C1 ? ? M ASN 361 M NAG 981 1_555 ? ? ? ? ? ? ? 1.444 ? covale10 covale ? ? A ASN 482 ND2 ? ? ? 1_555 Y NAG . C1 ? ? M ASN 482 M NAG 991 1_555 ? ? ? ? ? ? ? 1.677 ? covale11 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? M NAG 911 M NAG 913 1_555 ? ? ? ? ? ? ? 1.707 ? covale12 covale ? ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? M NAG 921 M NAG 923 1_555 ? ? ? ? ? ? ? 1.598 ? covale13 covale ? ? H NAG . O4 ? ? ? 1_555 J NAG . C1 ? ? M NAG 941 M NAG 943 1_555 ? ? ? ? ? ? ? 1.392 ? covale14 covale ? ? H NAG . O3 ? ? ? 1_555 I FUC . C1 ? ? M NAG 941 M FUC 942 1_555 ? ? ? ? ? ? ? 1.498 ? covale15 covale ? ? J NAG . O4 ? ? ? 1_555 K BMA . C1 ? ? M NAG 943 M BMA 944 1_555 ? ? ? ? ? ? ? 1.649 ? covale16 covale ? ? K BMA . O2 ? ? ? 1_555 L XYP . C1B ? ? M BMA 944 M XYP 945 1_555 ? ? ? ? ? ? ? 1.696 ? covale17 covale ? ? M NAG . O4 ? ? ? 1_555 O NAG . C1 ? ? M NAG 951 M NAG 953 1_555 ? ? ? ? ? ? ? 1.533 ? covale18 covale ? ? M NAG . O3 ? ? ? 1_555 N FUC . C1 ? ? M NAG 951 M FUC 952 1_555 ? ? ? ? ? ? ? 1.466 ? covale19 covale ? ? O NAG . O4 ? ? ? 1_555 P BMA . C1 ? ? M NAG 953 M BMA 954 1_555 ? ? ? ? ? ? ? 1.505 ? covale20 covale ? ? P BMA . O2 ? ? ? 1_555 Q XYP . C1B ? ? M BMA 954 M XYP 955 1_555 ? ? ? ? ? ? ? 1.535 ? covale21 covale ? ? P BMA . O3 ? ? ? 1_555 R MAN . C1 ? ? M BMA 954 M MAN 956 1_555 ? ? ? ? ? ? ? 1.556 ? covale22 covale ? ? P BMA . O6 ? ? ? 1_555 S MAN . C1 ? ? M BMA 954 M MAN 957 1_555 ? ? ? ? ? ? ? 1.660 ? covale23 covale ? ? T NAG . O4 ? ? ? 1_555 U NAG . C1 ? ? M NAG 961 M NAG 963 1_555 ? ? ? ? ? ? ? 1.799 ? covale24 covale ? ? W NAG . O4 ? ? ? 1_555 X NAG . C1 ? ? M NAG 981 M NAG 983 1_555 ? ? ? ? ? ? ? 1.570 ? metalc1 metalc ? ? AA ZN . ZN ? ? ? 1_555 A ASP 70 OD2 ? ? M ZN 1502 M ASP 70 3_656 ? ? ? ? ? ? ? 1.919 ? metalc2 metalc ? ? AA ZN . ZN ? ? ? 1_555 A ASP 70 OD2 ? ? M ZN 1502 M ASP 70 1_555 ? ? ? ? ? ? ? 1.973 ? metalc3 metalc ? ? AA ZN . ZN ? ? ? 1_555 A HIS 56 NE2 ? ? M ZN 1502 M HIS 56 3_656 ? ? ? ? ? ? ? 1.970 ? metalc4 metalc ? ? AA ZN . ZN ? ? ? 1_555 A HIS 56 NE2 ? ? M ZN 1502 M HIS 56 1_555 ? ? ? ? ? ? ? 1.926 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 LEU 10 A . ? LEU 10 M PRO 11 A ? PRO 11 M 1 -4.50 2 ALA 202 A . ? ALA 202 M PRO 203 A ? PRO 203 M 1 7.15 3 TRP 457 A . ? TRP 457 M ALA 458 A ? ALA 458 M 1 2.35 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details MA ? 6 ? MB ? 2 ? MC ? 2 ? MD ? 4 ? ME ? 4 ? MF ? 2 ? MG ? 2 ? MH ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense MA 1 2 ? parallel MA 2 3 ? parallel MA 3 4 ? parallel MA 4 5 ? parallel MA 5 6 ? parallel MB 1 2 ? parallel MC 1 2 ? anti-parallel MD 1 2 ? parallel MD 2 3 ? parallel MD 3 4 ? anti-parallel ME 1 2 ? parallel ME 2 3 ? parallel ME 3 4 ? parallel MF 1 2 ? anti-parallel MG 1 2 ? anti-parallel MH 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id MA 1 LYS A 251 ? GLY A 253 ? LYS M 251 GLY M 253 MA 2 TYR A 181 ? ILE A 185 ? TYR M 181 ILE M 185 MA 3 THR A 134 ? PHE A 140 ? THR M 134 PHE M 140 MA 4 GLY A 93 ? SER A 97 ? GLY M 93 SER M 97 MA 5 ILE A 30 ? ALA A 34 ? ILE M 30 ALA M 34 MA 6 GLY A 453 ? TRP A 457 ? GLY M 453 TRP M 457 MB 1 THR A 255 ? PRO A 263 ? THR M 255 PRO M 263 MB 2 LEU A 325 ? PRO A 337 ? LEU M 325 PRO M 337 MC 1 ALA A 355 ? THR A 358 ? ALA M 355 THR M 358 MC 2 LEU A 325 ? PRO A 337 ? LEU M 325 PRO M 337 MD 1 ASN A 450 ? VAL A 451 ? ASN M 450 VAL M 451 MD 2 LEU A 404 ? GLU A 409 ? LEU M 404 GLU M 409 MD 3 LEU A 325 ? PRO A 337 ? LEU M 325 PRO M 337 MD 4 ALA A 355 ? THR A 358 ? ALA M 355 THR M 358 ME 1 ASN A 450 ? VAL A 451 ? ASN M 450 VAL M 451 ME 2 LEU A 404 ? GLU A 409 ? LEU M 404 GLU M 409 ME 3 LEU A 325 ? PRO A 337 ? LEU M 325 PRO M 337 ME 4 THR A 255 ? PRO A 263 ? THR M 255 PRO M 263 MF 1 LEU A 370 ? GLU A 372 ? LEU M 370 GLU M 372 MF 2 ILE A 382 ? TYR A 383 ? ILE M 382 TYR M 383 MG 1 THR A 414 ? PRO A 415 ? THR M 414 PRO M 415 MG 2 VAL A 471 ? ARG A 472 ? VAL M 471 ARG M 472 MH 1 SER A 476 ? ASP A 479 ? SER M 476 ASP M 479 MH 2 ASN A 482 ? LEU A 488 ? ASN M 482 LEU M 488 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id MA 1 2 N GLY A 253 ? N GLY M 253 O TRP A 182 ? O TRP M 182 MA 2 3 N LEU A 183 ? N LEU M 183 O VAL A 137 ? O VAL M 137 MA 3 4 N PHE A 136 ? N PHE M 136 O TYR A 94 ? O TYR M 94 MA 4 5 N ARG A 95 ? N ARG M 95 O VAL A 33 ? O VAL M 33 MA 5 6 N GLY A 32 ? N GLY M 32 O TYR A 454 ? O TYR M 454 MB 1 2 N MET A 256 ? N MET M 256 O GLY A 326 ? O GLY M 326 MC 1 2 N THR A 358 ? N THR M 358 O TYR A 334 ? O TYR M 334 MD 1 2 O ASN A 450 ? O ASN M 450 N ILE A 405 ? N ILE M 405 MD 2 3 N TYR A 406 ? N TYR M 406 O LEU A 325 ? O LEU M 325 MD 3 4 N GLN A 336 ? N GLN M 336 O LYS A 356 ? O LYS M 356 ME 1 2 O ASN A 450 ? O ASN M 450 N ILE A 405 ? N ILE M 405 ME 2 3 N TYR A 406 ? N TYR M 406 O LEU A 325 ? O LEU M 325 ME 3 4 N ASN A 328 ? N ASN M 328 O MET A 256 ? O MET M 256 MF 1 2 N PHE A 371 ? N PHE M 371 O ILE A 382 ? O ILE M 382 MG 1 2 N THR A 414 ? N THR M 414 O ARG A 472 ? O ARG M 472 MH 1 2 O ASP A 479 ? O ASP M 479 N ASN A 482 ? N ASN M 482 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE SO4 M 1503' AC2 Software ? ? ? ? 14 'BINDING SITE FOR RESIDUE E18 M 1501' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG M 901' AC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG M 931' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG M 971' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG M 991' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN M 1502' AC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 M 1504' AC9 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 M 1505' BC1 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE SO4 M 1506' BC2 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE SO4 M 1507' BC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 M 1508' BC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 M 1509' BC5 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL M 2511' BC6 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE GOL M 2512' BC7 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE GOL M 2513' BC8 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL M 2514' BC9 Software ? ? ? ? 8 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 60 RESIDUES 961 TO 963' CC1 Software ? ? ? ? 6 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 90 RESIDUES 911 TO 913' CC2 Software ? ? ? ? 11 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 218 RESIDUES 921 TO 923' CC3 Software ? ? ? ? 15 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 265 RESIDUES 941 TO 945' CC4 Software ? ? ? ? 19 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 292 RESIDUES 951 TO 957' CC5 Software ? ? ? ? 12 'BINDING SITE FOR CHAIN M OF SUGAR BOUND TO ASN M 361 RESIDUES 981 TO 983' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 9 ARG A 194 ? ARG M 194 . ? 1_555 ? 2 AC1 9 ARG A 259 ? ARG M 259 . ? 1_555 ? 3 AC1 9 GLN A 333 ? GLN M 333 . ? 1_555 ? 4 AC1 9 E18 Z . ? E18 M 1501 . ? 1_555 ? 5 AC1 9 HOH MA . ? HOH M 3332 . ? 1_555 ? 6 AC1 9 HOH MA . ? HOH M 3334 . ? 1_555 ? 7 AC1 9 HOH MA . ? HOH M 3734 . ? 1_555 ? 8 AC1 9 HOH MA . ? HOH M 3735 . ? 1_555 ? 9 AC1 9 HOH MA . ? HOH M 3736 . ? 1_555 ? 10 AC2 14 GLN A 187 ? GLN M 187 . ? 1_555 ? 11 AC2 14 TYR A 189 ? TYR M 189 . ? 1_555 ? 12 AC2 14 SER A 190 ? SER M 190 . ? 1_555 ? 13 AC2 14 ARG A 194 ? ARG M 194 . ? 1_555 ? 14 AC2 14 ILE A 257 ? ILE M 257 . ? 1_555 ? 15 AC2 14 ARG A 259 ? ARG M 259 . ? 1_555 ? 16 AC2 14 TYR A 330 ? TYR M 330 . ? 1_555 ? 17 AC2 14 PHE A 371 ? PHE M 371 . ? 1_555 ? 18 AC2 14 GLU A 409 ? GLU M 409 . ? 1_555 ? 19 AC2 14 TRP A 457 ? TRP M 457 . ? 1_555 ? 20 AC2 14 GLU A 464 ? GLU M 464 . ? 1_555 ? 21 AC2 14 PHE A 473 ? PHE M 473 . ? 1_555 ? 22 AC2 14 SO4 BA . ? SO4 M 1503 . ? 1_555 ? 23 AC2 14 HOH MA . ? HOH M 3641 . ? 1_555 ? 24 AC3 8 THR A 17 ? THR M 17 . ? 1_555 ? 25 AC3 8 ASP A 18 ? ASP M 18 . ? 1_555 ? 26 AC3 8 ALA A 19 ? ALA M 19 . ? 1_555 ? 27 AC3 8 ASN A 21 ? ASN M 21 . ? 1_555 ? 28 AC3 8 SER A 24 ? SER M 24 . ? 1_555 ? 29 AC3 8 PRO A 501 ? PRO M 501 . ? 1_555 ? 30 AC3 8 HOH MA . ? HOH M 3683 . ? 1_555 ? 31 AC3 8 HOH MA . ? HOH M 3684 . ? 1_555 ? 32 AC4 6 LYS A 165 ? LYS M 165 . ? 1_555 ? 33 AC4 6 ASP A 239 ? ASP M 239 . ? 1_555 ? 34 AC4 6 LEU A 240 ? LEU M 240 . ? 1_555 ? 35 AC4 6 ASN A 244 ? ASN M 244 . ? 1_555 ? 36 AC4 6 HOH MA . ? HOH M 3366 . ? 1_555 ? 37 AC4 6 HOH MA . ? HOH M 3369 . ? 1_555 ? 38 AC5 3 SER A 344 ? SER M 344 . ? 1_555 ? 39 AC5 3 ASN A 346 ? ASN M 346 . ? 1_555 ? 40 AC5 3 HOH MA . ? HOH M 3504 . ? 1_555 ? 41 AC6 3 ASN A 482 ? ASN M 482 . ? 1_555 ? 42 AC6 3 ASP A 485 ? ASP M 485 . ? 1_555 ? 43 AC6 3 HOH MA . ? HOH M 3661 . ? 1_555 ? 44 AC7 4 HIS A 56 ? HIS M 56 . ? 1_555 ? 45 AC7 4 HIS A 56 ? HIS M 56 . ? 3_656 ? 46 AC7 4 ASP A 70 ? ASP M 70 . ? 3_656 ? 47 AC7 4 ASP A 70 ? ASP M 70 . ? 1_555 ? 48 AC8 5 ARG A 205 ? ARG M 205 . ? 1_555 ? 49 AC8 5 HOH MA . ? HOH M 3210 . ? 3_656 ? 50 AC8 5 HOH MA . ? HOH M 3739 . ? 1_555 ? 51 AC8 5 HOH MA . ? HOH M 3740 . ? 1_555 ? 52 AC8 5 HOH MA . ? HOH M 3741 . ? 1_555 ? 53 AC9 6 LYS A 108 ? LYS M 108 . ? 1_555 ? 54 AC9 6 ARG A 111 ? ARG M 111 . ? 1_555 ? 55 AC9 6 HOH MA . ? HOH M 3207 . ? 1_555 ? 56 AC9 6 HOH MA . ? HOH M 3286 . ? 3_656 ? 57 AC9 6 HOH MA . ? HOH M 3742 . ? 1_555 ? 58 AC9 6 HOH MA . ? HOH M 3743 . ? 1_555 ? 59 BC1 8 GLN A 7 ? GLN M 7 . ? 1_555 ? 60 BC1 8 GLU A 8 ? GLU M 8 . ? 1_555 ? 61 BC1 8 ASN A 9 ? ASN M 9 . ? 1_555 ? 62 BC1 8 HOH MA . ? HOH M 3008 . ? 1_555 ? 63 BC1 8 HOH MA . ? HOH M 3744 . ? 1_555 ? 64 BC1 8 HOH MA . ? HOH M 3746 . ? 1_555 ? 65 BC1 8 HOH MA . ? HOH M 3747 . ? 1_555 ? 66 BC1 8 HOH MA . ? HOH M 3748 . ? 1_555 ? 67 BC2 7 HIS A 270 ? HIS M 270 . ? 1_555 ? 68 BC2 7 ALA A 273 ? ALA M 273 . ? 1_555 ? 69 BC2 7 ARG A 277 ? ARG M 277 . ? 1_555 ? 70 BC2 7 HOH MA . ? HOH M 3749 . ? 1_555 ? 71 BC2 7 HOH MA . ? HOH M 3750 . ? 1_555 ? 72 BC2 7 HOH MA . ? HOH M 3751 . ? 1_555 ? 73 BC2 7 HOH MA . ? HOH M 3752 . ? 1_555 ? 74 BC3 6 ARG A 109 ? ARG M 109 . ? 1_555 ? 75 BC3 6 VAL A 113 ? VAL M 113 . ? 1_555 ? 76 BC3 6 GLU A 173 ? GLU M 173 . ? 1_555 ? 77 BC3 6 HOH MA . ? HOH M 3203 . ? 1_555 ? 78 BC3 6 HOH MA . ? HOH M 3753 . ? 1_555 ? 79 BC3 6 HOH MA . ? HOH M 3754 . ? 1_555 ? 80 BC4 4 ASN A 60 ? ASN M 60 . ? 1_555 ? 81 BC4 4 HIS A 66 ? HIS M 66 . ? 1_555 ? 82 BC4 4 NAG T . ? NAG M 961 . ? 1_555 ? 83 BC4 4 HOH MA . ? HOH M 3755 . ? 1_555 ? 84 BC5 8 ARG A 269 ? ARG M 269 . ? 1_555 ? 85 BC5 8 HIS A 270 ? HIS M 270 . ? 1_555 ? 86 BC5 8 ASN A 316 ? ASN M 316 . ? 6_564 ? 87 BC5 8 HOH MA . ? HOH M 3409 . ? 1_555 ? 88 BC5 8 HOH MA . ? HOH M 3467 . ? 6_564 ? 89 BC5 8 HOH MA . ? HOH M 3700 . ? 1_555 ? 90 BC5 8 HOH MA . ? HOH M 3756 . ? 1_555 ? 91 BC5 8 HOH MA . ? HOH M 3757 . ? 1_555 ? 92 BC6 9 ILE A 50 ? ILE M 50 . ? 1_555 ? 93 BC6 9 PHE A 54 ? PHE M 54 . ? 1_555 ? 94 BC6 9 ARG A 57 ? ARG M 57 . ? 1_555 ? 95 BC6 9 GLN A 146 ? GLN M 146 . ? 1_555 ? 96 BC6 9 GLN A 149 ? GLN M 149 . ? 1_555 ? 97 BC6 9 PRO A 203 ? PRO M 203 . ? 1_555 ? 98 BC6 9 TYR A 215 ? TYR M 215 . ? 1_555 ? 99 BC6 9 HOH MA . ? HOH M 3288 . ? 1_555 ? 100 BC6 9 HOH MA . ? HOH M 3758 . ? 1_555 ? 101 BC7 10 HIS A 247 ? HIS M 247 . ? 1_555 ? 102 BC7 10 GLY A 249 ? GLY M 249 . ? 1_555 ? 103 BC7 10 GLU A 280 ? GLU M 280 . ? 6_565 ? 104 BC7 10 GLN A 297 ? GLN M 297 . ? 6_565 ? 105 BC7 10 ILE A 298 ? ILE M 298 . ? 6_565 ? 106 BC7 10 FUC N . ? FUC M 952 . ? 6_565 ? 107 BC7 10 HOH MA . ? HOH M 3710 . ? 6_565 ? 108 BC7 10 HOH MA . ? HOH M 3759 . ? 1_555 ? 109 BC7 10 HOH MA . ? HOH M 3760 . ? 1_555 ? 110 BC7 10 HOH MA . ? HOH M 3761 . ? 1_555 ? 111 BC8 7 GLY A 132 ? GLY M 132 . ? 1_555 ? 112 BC8 7 THR A 134 ? THR M 134 . ? 1_555 ? 113 BC8 7 FUC N . ? FUC M 952 . ? 6_565 ? 114 BC8 7 NAG O . ? NAG M 953 . ? 6_565 ? 115 BC8 7 BMA P . ? BMA M 954 . ? 6_565 ? 116 BC8 7 HOH MA . ? HOH M 3763 . ? 1_555 ? 117 BC8 7 HOH MA . ? HOH M 3764 . ? 1_555 ? 118 BC9 8 ASN A 60 ? ASN M 60 . ? 1_555 ? 119 BC9 8 SER A 213 ? SER M 213 . ? 1_555 ? 120 BC9 8 SO4 HA . ? SO4 M 1509 . ? 1_555 ? 121 BC9 8 HOH MA . ? HOH M 3108 . ? 1_555 ? 122 BC9 8 HOH MA . ? HOH M 3725 . ? 1_555 ? 123 BC9 8 HOH MA . ? HOH M 3726 . ? 1_555 ? 124 BC9 8 HOH MA . ? HOH M 3727 . ? 1_555 ? 125 BC9 8 HOH MA . ? HOH M 3728 . ? 1_555 ? 126 CC1 6 ASN A 90 ? ASN M 90 . ? 1_555 ? 127 CC1 6 SER A 500 ? SER M 500 . ? 1_555 ? 128 CC1 6 HOH MA . ? HOH M 3685 . ? 1_555 ? 129 CC1 6 HOH MA . ? HOH M 3686 . ? 1_555 ? 130 CC1 6 HOH MA . ? HOH M 3687 . ? 1_555 ? 131 CC1 6 HOH MA . ? HOH M 3688 . ? 1_555 ? 132 CC2 11 SER A 207 ? SER M 207 . ? 1_555 ? 133 CC2 11 ASN A 218 ? ASN M 218 . ? 1_555 ? 134 CC2 11 THR A 221 ? THR M 221 . ? 1_555 ? 135 CC2 11 GLU A 305 ? GLU M 305 . ? 1_555 ? 136 CC2 11 HOH MA . ? HOH M 3354 . ? 1_555 ? 137 CC2 11 HOH MA . ? HOH M 3448 . ? 1_555 ? 138 CC2 11 HOH MA . ? HOH M 3689 . ? 1_555 ? 139 CC2 11 HOH MA . ? HOH M 3690 . ? 1_555 ? 140 CC2 11 HOH MA . ? HOH M 3691 . ? 1_555 ? 141 CC2 11 HOH MA . ? HOH M 3692 . ? 1_555 ? 142 CC2 11 HOH MA . ? HOH M 3693 . ? 1_555 ? 143 CC3 15 ASN A 265 ? ASN M 265 . ? 1_555 ? 144 CC3 15 ASP A 268 ? ASP M 268 . ? 1_555 ? 145 CC3 15 ALA A 362 ? ALA M 362 . ? 1_555 ? 146 CC3 15 HOH MA . ? HOH M 3409 . ? 1_555 ? 147 CC3 15 HOH MA . ? HOH M 3695 . ? 1_555 ? 148 CC3 15 HOH MA . ? HOH M 3696 . ? 1_555 ? 149 CC3 15 HOH MA . ? HOH M 3698 . ? 1_555 ? 150 CC3 15 HOH MA . ? HOH M 3699 . ? 1_555 ? 151 CC3 15 HOH MA . ? HOH M 3700 . ? 1_555 ? 152 CC3 15 HOH MA . ? HOH M 3701 . ? 1_555 ? 153 CC3 15 HOH MA . ? HOH M 3702 . ? 1_555 ? 154 CC3 15 HOH MA . ? HOH M 3703 . ? 1_555 ? 155 CC3 15 HOH MA . ? HOH M 3704 . ? 1_555 ? 156 CC3 15 HOH MA . ? HOH M 3705 . ? 1_555 ? 157 CC3 15 HOH MA . ? HOH M 3706 . ? 1_555 ? 158 CC4 19 ASN A 292 ? ASN M 292 . ? 1_555 ? 159 CC4 19 THR A 294 ? THR M 294 . ? 1_555 ? 160 CC4 19 GLN A 297 ? GLN M 297 . ? 1_555 ? 161 CC4 19 HOH MA . ? HOH M 3430 . ? 1_555 ? 162 CC4 19 HOH MA . ? HOH M 3707 . ? 1_555 ? 163 CC4 19 HOH MA . ? HOH M 3708 . ? 1_555 ? 164 CC4 19 HOH MA . ? HOH M 3709 . ? 1_555 ? 165 CC4 19 HOH MA . ? HOH M 3710 . ? 1_555 ? 166 CC4 19 HOH MA . ? HOH M 3711 . ? 1_555 ? 167 CC4 19 HOH MA . ? HOH M 3712 . ? 1_555 ? 168 CC4 19 HOH MA . ? HOH M 3713 . ? 1_555 ? 169 CC4 19 HOH MA . ? HOH M 3714 . ? 1_555 ? 170 CC4 19 HOH MA . ? HOH M 3716 . ? 1_555 ? 171 CC4 19 HOH MA . ? HOH M 3717 . ? 1_555 ? 172 CC4 19 HOH MA . ? HOH M 3718 . ? 1_555 ? 173 CC4 19 HOH MA . ? HOH M 3719 . ? 1_555 ? 174 CC4 19 HOH MA . ? HOH M 3720 . ? 1_555 ? 175 CC4 19 HOH MA . ? HOH M 3722 . ? 1_555 ? 176 CC4 19 HOH MA . ? HOH M 3723 . ? 1_555 ? 177 CC5 12 ASN A 265 ? ASN M 265 . ? 1_555 ? 178 CC5 12 ASP A 266 ? ASP M 266 . ? 1_555 ? 179 CC5 12 ASN A 361 ? ASN M 361 . ? 1_555 ? 180 CC5 12 SER A 363 ? SER M 363 . ? 1_555 ? 181 CC5 12 HIS A 365 ? HIS M 365 . ? 1_555 ? 182 CC5 12 HOH MA . ? HOH M 3399 . ? 1_555 ? 183 CC5 12 HOH MA . ? HOH M 3403 . ? 1_555 ? 184 CC5 12 HOH MA . ? HOH M 3405 . ? 1_555 ? 185 CC5 12 HOH MA . ? HOH M 3485 . ? 1_555 ? 186 CC5 12 HOH MA . ? HOH M 3729 . ? 1_555 ? 187 CC5 12 HOH MA . ? HOH M 3730 . ? 1_555 ? 188 CC5 12 HOH MA . ? HOH M 3731 . ? 1_555 ? # _database_PDB_matrix.entry_id 2WXD _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2WXD _atom_sites.fract_transf_matrix[1][1] 0.007340 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007269 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.012388 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLU A 1 3 ? 14.991 127.171 51.675 1.00 45.02 ? 3 GLU M N 1 ATOM 2 C CA . GLU A 1 3 ? 15.803 126.890 50.426 1.00 45.51 ? 3 GLU M CA 1 ATOM 3 C C . GLU A 1 3 ? 17.132 127.680 50.545 1.00 42.65 ? 3 GLU M C 1 ATOM 4 O O . GLU A 1 3 ? 17.130 128.816 51.039 1.00 42.80 ? 3 GLU M O 1 ATOM 5 C CB . GLU A 1 3 ? 15.003 127.226 49.144 1.00 46.41 ? 3 GLU M CB 1 ATOM 6 C CG . GLU A 1 3 ? 15.393 126.359 47.911 1.00 52.58 ? 3 GLU M CG 1 ATOM 7 C CD . GLU A 1 3 ? 16.605 126.933 47.197 1.00 60.03 ? 3 GLU M CD 1 ATOM 8 O OE1 . GLU A 1 3 ? 16.423 127.896 46.423 1.00 63.59 ? 3 GLU M OE1 1 ATOM 9 O OE2 . GLU A 1 3 ? 17.737 126.441 47.417 1.00 63.14 ? 3 GLU M OE2 1 ATOM 10 N N . ILE A 1 4 ? 18.263 127.058 50.222 1.00 37.92 ? 4 ILE M N 1 ATOM 11 C CA . ILE A 1 4 ? 19.601 127.682 50.524 1.00 34.72 ? 4 ILE M CA 1 ATOM 12 C C . ILE A 1 4 ? 20.295 128.077 49.226 1.00 30.74 ? 4 ILE M C 1 ATOM 13 O O . ILE A 1 4 ? 20.413 127.280 48.323 1.00 31.86 ? 4 ILE M O 1 ATOM 14 C CB . ILE A 1 4 ? 20.502 126.688 51.313 1.00 34.36 ? 4 ILE M CB 1 ATOM 15 C CG1 . ILE A 1 4 ? 19.996 126.480 52.739 1.00 37.09 ? 4 ILE M CG1 1 ATOM 16 C CG2 . ILE A 1 4 ? 21.932 127.155 51.469 1.00 31.52 ? 4 ILE M CG2 1 ATOM 17 C CD1 . ILE A 1 4 ? 20.666 125.380 53.373 1.00 39.40 ? 4 ILE M CD1 1 ATOM 18 N N . THR A 1 5 ? 20.711 129.331 49.118 1.00 28.21 ? 5 THR M N 1 ATOM 19 C CA . THR A 1 5 ? 21.394 129.846 47.927 1.00 26.45 ? 5 THR M CA 1 ATOM 20 C C . THR A 1 5 ? 22.799 130.198 48.361 1.00 22.33 ? 5 THR M C 1 ATOM 21 O O . THR A 1 5 ? 22.957 130.819 49.383 1.00 22.30 ? 5 THR M O 1 ATOM 22 C CB . THR A 1 5 ? 20.724 131.144 47.464 1.00 27.65 ? 5 THR M CB 1 ATOM 23 O OG1 . THR A 1 5 ? 19.422 130.750 47.017 1.00 34.65 ? 5 THR M OG1 1 ATOM 24 C CG2 . THR A 1 5 ? 21.448 131.762 46.258 1.00 31.92 ? 5 THR M CG2 1 ATOM 25 N N . CYS A 1 6 ? 23.784 129.649 47.689 1.00 17.38 ? 6 CYS M N 1 ATOM 26 C CA . CYS A 1 6 ? 25.208 129.973 48.010 1.00 16.36 ? 6 CYS M CA 1 ATOM 27 C C . CYS A 1 6 ? 25.817 130.614 46.770 1.00 15.36 ? 6 CYS M C 1 ATOM 28 O O . CYS A 1 6 ? 25.604 130.253 45.638 1.00 20.07 ? 6 CYS M O 1 ATOM 29 C CB . CYS A 1 6 ? 25.971 128.688 48.282 1.00 14.19 ? 6 CYS M CB 1 ATOM 30 S SG . CYS A 1 6 ? 25.359 127.861 49.801 1.00 19.94 ? 6 CYS M SG 1 ATOM 31 N N . GLN A 1 7 ? 26.729 131.494 47.034 1.00 14.52 ? 7 GLN M N 1 ATOM 32 C CA . GLN A 1 7 ? 27.492 132.192 46.012 1.00 13.01 ? 7 GLN M CA 1 ATOM 33 C C . GLN A 1 7 ? 28.728 131.441 45.561 1.00 12.67 ? 7 GLN M C 1 ATOM 34 O O . GLN A 1 7 ? 29.404 130.807 46.357 1.00 12.61 ? 7 GLN M O 1 ATOM 35 C CB . GLN A 1 7 ? 27.957 133.453 46.613 1.00 15.52 ? 7 GLN M CB 1 ATOM 36 C CG . GLN A 1 7 ? 26.796 134.462 47.031 1.00 18.89 ? 7 GLN M CG 1 ATOM 37 C CD . GLN A 1 7 ? 27.190 135.397 48.131 1.00 17.08 ? 7 GLN M CD 1 ATOM 38 O OE1 . GLN A 1 7 ? 28.011 135.088 49.042 1.00 20.23 ? 7 GLN M OE1 1 ATOM 39 N NE2 . GLN A 1 7 ? 26.535 136.560 48.109 1.00 21.73 ? 7 GLN M NE2 1 ATOM 40 N N . GLU A 1 8 ? 29.040 131.558 44.273 1.00 11.79 ? 8 GLU M N 1 ATOM 41 C CA . GLU A 1 8 ? 30.128 130.899 43.608 1.00 11.31 ? 8 GLU M CA 1 ATOM 42 C C . GLU A 1 8 ? 31.238 131.873 43.221 1.00 12.62 ? 8 GLU M C 1 ATOM 43 O O . GLU A 1 8 ? 32.370 131.465 42.942 1.00 12.60 ? 8 GLU M O 1 ATOM 44 C CB . GLU A 1 8 ? 29.691 130.167 42.387 1.00 12.63 ? 8 GLU M CB 1 ATOM 45 C CG . GLU A 1 8 ? 28.687 129.065 42.814 1.00 13.50 ? 8 GLU M CG 1 ATOM 46 C CD . GLU A 1 8 ? 28.431 128.113 41.733 1.00 22.38 ? 8 GLU M CD 1 ATOM 47 O OE1 . GLU A 1 8 ? 29.293 127.355 41.189 1.00 17.33 ? 8 GLU M OE1 1 ATOM 48 O OE2 . GLU A 1 8 ? 27.232 128.113 41.369 1.00 33.15 ? 8 GLU M OE2 1 ATOM 49 N N . ASN A 1 9 ? 30.865 133.144 43.078 1.00 11.85 ? 9 ASN M N 1 ATOM 50 C CA . ASN A 1 9 ? 31.801 134.168 42.515 1.00 12.19 ? 9 ASN M CA 1 ATOM 51 C C . ASN A 1 9 ? 31.856 135.403 43.426 1.00 12.70 ? 9 ASN M C 1 ATOM 52 O O . ASN A 1 9 ? 30.926 135.696 44.159 1.00 13.58 ? 9 ASN M O 1 ATOM 53 C CB . ASN A 1 9 ? 31.212 134.668 41.187 1.00 13.07 ? 9 ASN M CB 1 ATOM 54 C CG . ASN A 1 9 ? 30.864 133.544 40.231 1.00 15.96 ? 9 ASN M CG 1 ATOM 55 O OD1 . ASN A 1 9 ? 31.760 132.962 39.667 1.00 16.43 ? 9 ASN M OD1 1 ATOM 56 N ND2 . ASN A 1 9 ? 29.542 133.269 40.017 1.00 17.42 ? 9 ASN M ND2 1 ATOM 57 N N . LEU A 1 10 ? 32.984 136.118 43.381 1.00 11.94 ? 10 LEU M N 1 ATOM 58 C CA . LEU A 1 10 ? 33.111 137.365 44.073 1.00 11.31 ? 10 LEU M CA 1 ATOM 59 C C . LEU A 1 10 ? 32.037 138.340 43.548 1.00 12.75 ? 10 LEU M C 1 ATOM 60 O O . LEU A 1 10 ? 31.704 138.334 42.381 1.00 13.49 ? 10 LEU M O 1 ATOM 61 C CB . LEU A 1 10 ? 34.497 137.959 43.876 1.00 14.30 ? 10 LEU M CB 1 ATOM 62 C CG . LEU A 1 10 ? 35.660 137.274 44.548 1.00 14.18 ? 10 LEU M CG 1 ATOM 63 C CD1 . LEU A 1 10 ? 36.967 137.851 44.044 1.00 14.52 ? 10 LEU M CD1 1 ATOM 64 C CD2 . LEU A 1 10 ? 35.557 137.348 46.097 1.00 20.54 ? 10 LEU M CD2 1 ATOM 65 N N . PRO A 1 11 ? 31.518 139.187 44.439 1.00 13.05 ? 11 PRO M N 1 ATOM 66 C CA . PRO A 1 11 ? 31.752 139.276 45.876 1.00 14.62 ? 11 PRO M CA 1 ATOM 67 C C . PRO A 1 11 ? 30.842 138.327 46.638 1.00 14.65 ? 11 PRO M C 1 ATOM 68 O O . PRO A 1 11 ? 29.752 137.982 46.168 1.00 15.00 ? 11 PRO M O 1 ATOM 69 C CB . PRO A 1 11 ? 31.407 140.732 46.179 1.00 16.40 ? 11 PRO M CB 1 ATOM 70 C CG . PRO A 1 11 ? 30.477 141.095 45.250 1.00 18.55 ? 11 PRO M CG 1 ATOM 71 C CD . PRO A 1 11 ? 30.645 140.288 43.961 1.00 14.17 ? 11 PRO M CD 1 ATOM 72 N N . PHE A 1 12 ? 31.370 137.866 47.772 1.00 14.78 ? 12 PHE M N 1 ATOM 73 C CA . PHE A 1 12 ? 30.637 137.045 48.710 1.00 13.15 ? 12 PHE M CA 1 ATOM 74 C C . PHE A 1 12 ? 30.011 137.940 49.773 1.00 16.14 ? 12 PHE M C 1 ATOM 75 O O . PHE A 1 12 ? 30.669 138.875 50.234 1.00 17.25 ? 12 PHE M O 1 ATOM 76 C CB . PHE A 1 12 ? 31.591 136.033 49.347 1.00 12.09 ? 12 PHE M CB 1 ATOM 77 C CG . PHE A 1 12 ? 32.149 135.061 48.365 1.00 10.24 ? 12 PHE M CG 1 ATOM 78 C CD1 . PHE A 1 12 ? 31.411 134.096 47.812 1.00 18.10 ? 12 PHE M CD1 1 ATOM 79 C CD2 . PHE A 1 12 ? 33.430 135.194 47.824 1.00 16.20 ? 12 PHE M CD2 1 ATOM 80 C CE1 . PHE A 1 12 ? 31.889 133.222 46.845 1.00 16.81 ? 12 PHE M CE1 1 ATOM 81 C CE2 . PHE A 1 12 ? 33.940 134.269 46.835 1.00 16.89 ? 12 PHE M CE2 1 ATOM 82 C CZ . PHE A 1 12 ? 33.152 133.314 46.381 1.00 13.80 ? 12 PHE M CZ 1 ATOM 83 N N . THR A 1 13 ? 28.869 137.476 50.253 1.00 15.45 ? 13 THR M N 1 ATOM 84 C CA . THR A 1 13 ? 28.209 138.161 51.385 1.00 16.69 ? 13 THR M CA 1 ATOM 85 C C . THR A 1 13 ? 28.051 137.226 52.582 1.00 19.06 ? 13 THR M C 1 ATOM 86 O O . THR A 1 13 ? 27.408 137.608 53.539 1.00 19.82 ? 13 THR M O 1 ATOM 87 C CB . THR A 1 13 ? 26.845 138.656 50.905 1.00 17.42 ? 13 THR M CB 1 ATOM 88 O OG1 . THR A 1 13 ? 26.029 137.577 50.450 1.00 20.94 ? 13 THR M OG1 1 ATOM 89 C CG2 . THR A 1 13 ? 27.115 139.697 49.771 1.00 24.26 ? 13 THR M CG2 1 ATOM 90 N N . CYS A 1 14 ? 28.667 136.022 52.561 1.00 16.40 ? 14 CYS M N 1 ATOM 91 C CA . CYS A 1 14 ? 28.496 135.028 53.643 1.00 16.37 ? 14 CYS M CA 1 ATOM 92 C C . CYS A 1 14 ? 29.325 135.266 54.867 1.00 16.82 ? 14 CYS M C 1 ATOM 93 O O . CYS A 1 14 ? 29.240 134.448 55.738 1.00 18.44 ? 14 CYS M O 1 ATOM 94 C CB . CYS A 1 14 ? 28.741 133.612 53.132 1.00 15.96 ? 14 CYS M CB 1 ATOM 95 S SG . CYS A 1 14 ? 30.323 133.448 52.057 1.00 22.08 ? 14 CYS M SG 1 ATOM 96 N N . GLY A 1 15 ? 30.085 136.362 54.925 1.00 14.96 ? 15 GLY M N 1 ATOM 97 C CA . GLY A 1 15 ? 30.811 136.726 56.072 1.00 18.24 ? 15 GLY M CA 1 ATOM 98 C C . GLY A 1 15 ? 29.970 137.345 57.167 1.00 20.02 ? 15 GLY M C 1 ATOM 99 O O . GLY A 1 15 ? 30.508 137.712 58.153 1.00 20.87 ? 15 GLY M O 1 ATOM 100 N N . ASN A 1 16 ? 28.681 137.567 56.868 1.00 20.04 ? 16 ASN M N 1 ATOM 101 C CA . ASN A 1 16 ? 27.771 138.158 57.801 1.00 20.18 ? 16 ASN M CA 1 ATOM 102 C C . ASN A 1 16 ? 27.108 137.098 58.587 1.00 17.75 ? 16 ASN M C 1 ATOM 103 O O . ASN A 1 16 ? 26.361 136.250 58.143 1.00 19.74 ? 16 ASN M O 1 ATOM 104 C CB . ASN A 1 16 ? 26.743 138.974 57.020 1.00 22.54 ? 16 ASN M CB 1 ATOM 105 C CG . ASN A 1 16 ? 25.767 139.702 57.949 1.00 29.69 ? 16 ASN M CG 1 ATOM 106 O OD1 . ASN A 1 16 ? 25.641 139.406 59.135 1.00 26.80 ? 16 ASN M OD1 1 ATOM 107 N ND2 . ASN A 1 16 ? 25.032 140.673 57.360 1.00 39.47 ? 16 ASN M ND2 1 ATOM 108 N N . THR A 1 17 ? 27.486 137.060 59.861 1.00 17.66 ? 17 THR M N 1 ATOM 109 C CA . THR A 1 17 ? 27.063 135.994 60.731 1.00 18.23 ? 17 THR M CA 1 ATOM 110 C C . THR A 1 17 ? 25.565 136.047 61.120 1.00 22.99 ? 17 THR M C 1 ATOM 111 O O . THR A 1 17 ? 25.034 135.118 61.707 1.00 25.24 ? 17 THR M O 1 ATOM 112 C CB . THR A 1 17 ? 27.890 135.880 61.958 1.00 19.99 ? 17 THR M CB 1 ATOM 113 O OG1 . THR A 1 17 ? 27.820 137.054 62.778 1.00 21.19 ? 17 THR M OG1 1 ATOM 114 C CG2 . THR A 1 17 ? 29.444 135.629 61.702 1.00 19.36 ? 17 THR M CG2 1 ATOM 115 N N . ASP A 1 18 ? 24.918 137.127 60.717 1.00 25.83 ? 18 ASP M N 1 ATOM 116 C CA . ASP A 1 18 ? 23.458 137.090 60.702 1.00 31.65 ? 18 ASP M CA 1 ATOM 117 C C . ASP A 1 18 ? 22.882 136.119 59.691 1.00 32.78 ? 18 ASP M C 1 ATOM 118 O O . ASP A 1 18 ? 21.755 135.700 59.875 1.00 37.12 ? 18 ASP M O 1 ATOM 119 C CB . ASP A 1 18 ? 22.882 138.461 60.307 1.00 34.20 ? 18 ASP M CB 1 ATOM 120 C CG . ASP A 1 18 ? 23.205 139.572 61.315 1.00 38.17 ? 18 ASP M CG 1 ATOM 121 O OD1 . ASP A 1 18 ? 23.620 139.263 62.472 1.00 37.82 ? 18 ASP M OD1 1 ATOM 122 O OD2 . ASP A 1 18 ? 23.071 140.763 60.867 1.00 41.50 ? 18 ASP M OD2 1 ATOM 123 N N . ALA A 1 19 ? 23.572 135.883 58.584 1.00 32.73 ? 19 ALA M N 1 ATOM 124 C CA . ALA A 1 19 ? 23.062 135.084 57.473 1.00 32.46 ? 19 ALA M CA 1 ATOM 125 C C . ALA A 1 19 ? 23.623 133.648 57.664 1.00 30.19 ? 19 ALA M C 1 ATOM 126 O O . ALA A 1 19 ? 22.958 132.660 57.368 1.00 32.19 ? 19 ALA M O 1 ATOM 127 C CB . ALA A 1 19 ? 23.524 135.632 56.152 1.00 31.65 ? 19 ALA M CB 1 ATOM 128 N N . LEU A 1 20 ? 24.863 133.515 58.143 1.00 22.38 ? 20 LEU M N 1 ATOM 129 C CA . LEU A 1 20 ? 25.481 132.153 58.216 1.00 20.18 ? 20 LEU M CA 1 ATOM 130 C C . LEU A 1 20 ? 26.278 132.092 59.510 1.00 15.36 ? 20 LEU M C 1 ATOM 131 O O . LEU A 1 20 ? 27.182 132.932 59.747 1.00 14.88 ? 20 LEU M O 1 ATOM 132 C CB . LEU A 1 20 ? 26.395 131.906 56.989 1.00 19.14 ? 20 LEU M CB 1 ATOM 133 C CG . LEU A 1 20 ? 27.216 130.631 56.996 1.00 18.91 ? 20 LEU M CG 1 ATOM 134 C CD1 . LEU A 1 20 ? 26.291 129.432 56.858 1.00 21.34 ? 20 LEU M CD1 1 ATOM 135 C CD2 . LEU A 1 20 ? 28.283 130.719 55.798 1.00 19.15 ? 20 LEU M CD2 1 ATOM 136 N N . ASN A 1 21 ? 26.004 131.050 60.343 1.00 16.44 ? 21 ASN M N 1 ATOM 137 C CA . ASN A 1 21 ? 26.715 130.883 61.550 1.00 15.70 ? 21 ASN M CA 1 ATOM 138 C C . ASN A 1 21 ? 26.581 129.425 61.988 1.00 14.99 ? 21 ASN M C 1 ATOM 139 O O . ASN A 1 21 ? 25.922 128.616 61.327 1.00 19.78 ? 21 ASN M O 1 ATOM 140 C CB . ASN A 1 21 ? 26.178 131.852 62.630 1.00 16.19 ? 21 ASN M CB 1 ATOM 141 C CG . ASN A 1 21 ? 24.723 131.650 62.826 1.00 18.22 ? 21 ASN M CG 1 ATOM 142 O OD1 . ASN A 1 21 ? 24.299 130.537 63.281 1.00 18.99 ? 21 ASN M OD1 1 ATOM 143 N ND2 . ASN A 1 21 ? 23.957 132.729 62.590 1.00 20.37 ? 21 ASN M ND2 1 ATOM 144 N N . SER A 1 22 ? 27.148 129.101 63.086 1.00 15.45 ? 22 SER M N 1 ATOM 145 C CA . SER A 1 22 ? 27.200 127.673 63.572 1.00 14.21 ? 22 SER M CA 1 ATOM 146 C C . SER A 1 22 ? 25.731 127.155 63.813 1.00 16.60 ? 22 SER M C 1 ATOM 147 O O . SER A 1 22 ? 25.550 125.915 63.746 1.00 16.60 ? 22 SER M O 1 ATOM 148 C CB . SER A 1 22 ? 28.005 127.466 64.773 1.00 16.16 ? 22 SER M CB 1 ATOM 149 O OG . SER A 1 22 ? 27.483 128.230 65.870 1.00 16.78 ? 22 SER M OG 1 ATOM 150 N N . SER A 1 23 ? 24.790 128.025 64.168 1.00 19.16 ? 23 SER M N 1 ATOM 151 C CA . SER A 1 23 ? 23.406 127.606 64.345 1.00 19.05 ? 23 SER M CA 1 ATOM 152 C C . SER A 1 23 ? 22.694 127.214 63.134 1.00 19.36 ? 23 SER M C 1 ATOM 153 O O . SER A 1 23 ? 21.688 126.565 63.240 1.00 19.31 ? 23 SER M O 1 ATOM 154 C CB . SER A 1 23 ? 22.517 128.721 64.987 1.00 22.11 ? 23 SER M CB 1 ATOM 155 O OG . SER A 1 23 ? 23.064 128.867 66.259 1.00 30.45 ? 23 SER M OG 1 ATOM 156 N N . SER A 1 24 ? 23.262 127.515 61.954 1.00 19.66 ? 24 SER M N 1 ATOM 157 C CA . SER A 1 24 ? 22.800 127.056 60.730 1.00 20.66 ? 24 SER M CA 1 ATOM 158 C C . SER A 1 24 ? 22.928 125.527 60.585 1.00 20.11 ? 24 SER M C 1 ATOM 159 O O . SER A 1 24 ? 22.279 124.900 59.774 1.00 23.25 ? 24 SER M O 1 ATOM 160 C CB . SER A 1 24 ? 23.565 127.818 59.541 1.00 20.31 ? 24 SER M CB 1 ATOM 161 O OG . SER A 1 24 ? 23.624 129.318 59.693 1.00 22.14 ? 24 SER M OG 1 ATOM 162 N N . PHE A 1 25 ? 23.884 124.938 61.326 1.00 16.08 ? 25 PHE M N 1 ATOM 163 C CA . PHE A 1 25 ? 24.177 123.546 61.343 1.00 15.34 ? 25 PHE M CA 1 ATOM 164 C C . PHE A 1 25 ? 23.544 122.817 62.484 1.00 16.95 ? 25 PHE M C 1 ATOM 165 O O . PHE A 1 25 ? 23.041 123.507 63.416 1.00 18.37 ? 25 PHE M O 1 ATOM 166 C CB . PHE A 1 25 ? 25.763 123.392 61.462 1.00 13.72 ? 25 PHE M CB 1 ATOM 167 C CG . PHE A 1 25 ? 26.520 123.879 60.236 1.00 12.70 ? 25 PHE M CG 1 ATOM 168 C CD1 . PHE A 1 25 ? 26.676 125.188 59.919 1.00 13.94 ? 25 PHE M CD1 1 ATOM 169 C CD2 . PHE A 1 25 ? 27.077 122.957 59.302 1.00 12.26 ? 25 PHE M CD2 1 ATOM 170 C CE1 . PHE A 1 25 ? 27.386 125.630 58.856 1.00 12.79 ? 25 PHE M CE1 1 ATOM 171 C CE2 . PHE A 1 25 ? 27.777 123.403 58.229 1.00 12.21 ? 25 PHE M CE2 1 ATOM 172 C CZ . PHE A 1 25 ? 27.926 124.742 57.958 1.00 13.99 ? 25 PHE M CZ 1 ATOM 173 N N . SER A 1 26 ? 23.646 121.490 62.517 1.00 17.45 ? 26 SER M N 1 ATOM 174 C CA . SER A 1 26 ? 23.049 120.756 63.645 1.00 20.07 ? 26 SER M CA 1 ATOM 175 C C . SER A 1 26 ? 23.765 121.085 64.936 1.00 20.03 ? 26 SER M C 1 ATOM 176 O O . SER A 1 26 ? 24.931 121.460 64.998 1.00 18.86 ? 26 SER M O 1 ATOM 177 C CB . SER A 1 26 ? 23.036 119.226 63.462 1.00 22.13 ? 26 SER M CB 1 ATOM 178 O OG . SER A 1 26 ? 22.386 118.881 62.186 1.00 30.11 ? 26 SER M OG 1 ATOM 179 N N . SER A 1 27 ? 23.046 120.971 66.076 1.00 20.22 ? 27 SER M N 1 ATOM 180 C CA . SER A 1 27 ? 23.673 121.382 67.295 1.00 21.15 ? 27 SER M CA 1 ATOM 181 C C . SER A 1 27 ? 24.942 120.593 67.707 1.00 21.56 ? 27 SER M C 1 ATOM 182 O O . SER A 1 27 ? 25.816 121.102 68.382 1.00 23.04 ? 27 SER M O 1 ATOM 183 C CB . SER A 1 27 ? 22.650 121.452 68.501 1.00 25.91 ? 27 SER M CB 1 ATOM 184 O OG . SER A 1 27 ? 22.446 120.155 68.871 1.00 34.11 ? 27 SER M OG 1 ATOM 185 N N . ASP A 1 28 ? 25.055 119.399 67.308 1.00 19.54 ? 28 ASP M N 1 ATOM 186 C CA . ASP A 1 28 ? 26.205 118.567 67.714 1.00 19.48 ? 28 ASP M CA 1 ATOM 187 C C . ASP A 1 28 ? 27.496 118.792 66.787 1.00 19.47 ? 28 ASP M C 1 ATOM 188 O O . ASP A 1 28 ? 28.563 118.248 67.044 1.00 20.75 ? 28 ASP M O 1 ATOM 189 C CB . ASP A 1 28 ? 25.778 117.095 67.788 1.00 22.26 ? 28 ASP M CB 1 ATOM 190 C CG . ASP A 1 28 ? 25.406 116.459 66.449 1.00 29.51 ? 28 ASP M CG 1 ATOM 191 O OD1 . ASP A 1 28 ? 25.180 117.192 65.441 1.00 34.52 ? 28 ASP M OD1 1 ATOM 192 O OD2 . ASP A 1 28 ? 25.348 115.152 66.404 1.00 36.28 ? 28 ASP M OD2 1 ATOM 193 N N . PHE A 1 29 ? 27.317 119.663 65.811 1.00 15.97 ? 29 PHE M N 1 ATOM 194 C CA . PHE A 1 29 ? 28.329 119.790 64.751 1.00 11.90 ? 29 PHE M CA 1 ATOM 195 C C . PHE A 1 29 ? 29.587 120.365 65.379 1.00 11.59 ? 29 PHE M C 1 ATOM 196 O O . PHE A 1 29 ? 29.514 121.291 66.145 1.00 15.04 ? 29 PHE M O 1 ATOM 197 C CB . PHE A 1 29 ? 27.828 120.654 63.651 1.00 11.54 ? 29 PHE M CB 1 ATOM 198 C CG . PHE A 1 29 ? 28.579 120.520 62.347 1.00 10.68 ? 29 PHE M CG 1 ATOM 199 C CD1 . PHE A 1 29 ? 29.674 121.343 62.070 1.00 11.29 ? 29 PHE M CD1 1 ATOM 200 C CD2 . PHE A 1 29 ? 28.198 119.613 61.364 1.00 12.14 ? 29 PHE M CD2 1 ATOM 201 C CE1 . PHE A 1 29 ? 30.332 121.251 60.815 1.00 10.91 ? 29 PHE M CE1 1 ATOM 202 C CE2 . PHE A 1 29 ? 28.800 119.559 60.166 1.00 12.98 ? 29 PHE M CE2 1 ATOM 203 C CZ . PHE A 1 29 ? 29.892 120.376 59.868 1.00 10.43 ? 29 PHE M CZ 1 ATOM 204 N N . ILE A 1 30 ? 30.743 119.817 65.030 1.00 9.32 ? 30 ILE M N 1 ATOM 205 C CA . ILE A 1 30 ? 32.038 120.244 65.587 1.00 9.17 ? 30 ILE M CA 1 ATOM 206 C C . ILE A 1 30 ? 32.682 121.264 64.658 1.00 9.61 ? 30 ILE M C 1 ATOM 207 O O . ILE A 1 30 ? 32.720 121.086 63.476 1.00 11.63 ? 30 ILE M O 1 ATOM 208 C CB A ILE A 1 30 ? 32.938 119.038 65.826 0.70 9.07 ? 30 ILE M CB 1 ATOM 209 C CB B ILE A 1 30 ? 33.033 119.057 65.838 0.30 9.36 ? 30 ILE M CB 1 ATOM 210 C CG1 A ILE A 1 30 ? 32.449 118.300 67.055 0.70 10.11 ? 30 ILE M CG1 1 ATOM 211 C CG1 B ILE A 1 30 ? 32.374 117.862 66.526 0.30 9.16 ? 30 ILE M CG1 1 ATOM 212 C CG2 A ILE A 1 30 ? 34.484 119.502 65.829 0.70 8.03 ? 30 ILE M CG2 1 ATOM 213 C CG2 B ILE A 1 30 ? 34.242 119.535 66.685 0.30 8.38 ? 30 ILE M CG2 1 ATOM 214 C CD1 A ILE A 1 30 ? 33.065 116.857 67.163 0.70 11.55 ? 30 ILE M CD1 1 ATOM 215 C CD1 B ILE A 1 30 ? 32.541 117.874 68.048 0.30 11.36 ? 30 ILE M CD1 1 ATOM 216 N N . PHE A 1 31 ? 33.155 122.357 65.238 1.00 7.85 ? 31 PHE M N 1 ATOM 217 C CA . PHE A 1 31 ? 33.881 123.396 64.497 1.00 9.92 ? 31 PHE M CA 1 ATOM 218 C C . PHE A 1 31 ? 35.245 123.594 65.165 1.00 8.39 ? 31 PHE M C 1 ATOM 219 O O . PHE A 1 31 ? 35.391 123.737 66.385 1.00 11.37 ? 31 PHE M O 1 ATOM 220 C CB . PHE A 1 31 ? 33.161 124.746 64.467 1.00 12.45 ? 31 PHE M CB 1 ATOM 221 C CG . PHE A 1 31 ? 31.963 124.734 63.521 1.00 10.85 ? 31 PHE M CG 1 ATOM 222 C CD1 . PHE A 1 31 ? 32.171 124.767 62.177 1.00 12.54 ? 31 PHE M CD1 1 ATOM 223 C CD2 . PHE A 1 31 ? 30.682 124.701 64.003 1.00 11.33 ? 31 PHE M CD2 1 ATOM 224 C CE1 . PHE A 1 31 ? 31.138 124.718 61.302 1.00 12.64 ? 31 PHE M CE1 1 ATOM 225 C CE2 . PHE A 1 31 ? 29.626 124.660 63.118 1.00 9.90 ? 31 PHE M CE2 1 ATOM 226 C CZ . PHE A 1 31 ? 29.832 124.624 61.810 1.00 11.16 ? 31 PHE M CZ 1 ATOM 227 N N . GLY A 1 32 ? 36.266 123.619 64.280 1.00 10.06 ? 32 GLY M N 1 ATOM 228 C CA . GLY A 1 32 ? 37.574 123.853 64.798 1.00 11.05 ? 32 GLY M CA 1 ATOM 229 C C . GLY A 1 32 ? 38.555 124.187 63.700 1.00 8.20 ? 32 GLY M C 1 ATOM 230 O O . GLY A 1 32 ? 38.195 124.697 62.658 1.00 8.06 ? 32 GLY M O 1 ATOM 231 N N . VAL A 1 33 ? 39.828 123.865 64.015 1.00 8.09 ? 33 VAL M N 1 ATOM 232 C CA . VAL A 1 33 ? 40.987 124.166 63.143 1.00 8.52 ? 33 VAL M CA 1 ATOM 233 C C . VAL A 1 33 ? 41.900 122.981 63.294 1.00 8.23 ? 33 VAL M C 1 ATOM 234 O O . VAL A 1 33 ? 41.738 122.089 64.121 1.00 9.25 ? 33 VAL M O 1 ATOM 235 C CB . VAL A 1 33 ? 41.691 125.513 63.506 1.00 8.99 ? 33 VAL M CB 1 ATOM 236 C CG1 . VAL A 1 33 ? 40.794 126.716 63.167 1.00 10.31 ? 33 VAL M CG1 1 ATOM 237 C CG2 . VAL A 1 33 ? 42.110 125.520 64.959 1.00 11.39 ? 33 VAL M CG2 1 ATOM 238 N N . ALA A 1 34 ? 42.900 122.952 62.426 1.00 8.25 ? 34 ALA M N 1 ATOM 239 C CA . ALA A 1 34 ? 43.822 121.834 62.241 1.00 6.81 ? 34 ALA M CA 1 ATOM 240 C C . ALA A 1 34 ? 45.239 122.333 62.120 1.00 9.51 ? 34 ALA M C 1 ATOM 241 O O . ALA A 1 34 ? 45.573 123.495 61.841 1.00 9.00 ? 34 ALA M O 1 ATOM 242 C CB . ALA A 1 34 ? 43.482 121.031 60.986 1.00 9.42 ? 34 ALA M CB 1 ATOM 243 N N . SER A 1 35 ? 46.121 121.388 62.416 1.00 7.52 ? 35 SER M N 1 ATOM 244 C CA . SER A 1 35 ? 47.572 121.575 62.375 1.00 7.56 ? 35 SER M CA 1 ATOM 245 C C . SER A 1 35 ? 48.271 120.240 62.112 1.00 7.37 ? 35 SER M C 1 ATOM 246 O O . SER A 1 35 ? 47.615 119.199 62.013 1.00 8.24 ? 35 SER M O 1 ATOM 247 C CB . SER A 1 35 ? 48.158 122.175 63.626 1.00 7.13 ? 35 SER M CB 1 ATOM 248 O OG . SER A 1 35 ? 48.109 121.179 64.686 1.00 8.25 ? 35 SER M OG 1 ATOM 249 N N . SER A 1 36 ? 49.601 120.207 61.897 1.00 7.52 ? 36 SER M N 1 ATOM 250 C CA . SER A 1 36 ? 50.380 118.986 61.878 1.00 6.76 ? 36 SER M CA 1 ATOM 251 C C . SER A 1 36 ? 51.733 119.194 62.531 1.00 7.49 ? 36 SER M C 1 ATOM 252 O O . SER A 1 36 ? 52.220 120.316 62.625 1.00 8.18 ? 36 SER M O 1 ATOM 253 C CB . SER A 1 36 ? 50.552 118.418 60.501 1.00 9.27 ? 36 SER M CB 1 ATOM 254 O OG . SER A 1 36 ? 51.692 119.003 59.800 1.00 8.20 ? 36 SER M OG 1 ATOM 255 N N . ALA A 1 37 ? 52.288 118.089 62.983 1.00 7.44 ? 37 ALA M N 1 ATOM 256 C CA . ALA A 1 37 ? 53.455 118.210 63.921 1.00 6.57 ? 37 ALA M CA 1 ATOM 257 C C . ALA A 1 37 ? 54.710 118.744 63.251 1.00 5.76 ? 37 ALA M C 1 ATOM 258 O O . ALA A 1 37 ? 55.386 119.597 63.873 1.00 7.63 ? 37 ALA M O 1 ATOM 259 C CB . ALA A 1 37 ? 53.775 116.751 64.512 1.00 8.20 ? 37 ALA M CB 1 ATOM 260 N N . TYR A 1 38 ? 55.033 118.290 62.066 1.00 7.07 ? 38 TYR M N 1 ATOM 261 C CA . TYR A 1 38 ? 56.234 118.818 61.433 1.00 6.93 ? 38 TYR M CA 1 ATOM 262 C C . TYR A 1 38 ? 56.095 120.325 61.235 1.00 8.31 ? 38 TYR M C 1 ATOM 263 O O . TYR A 1 38 ? 57.043 121.118 61.353 1.00 8.32 ? 38 TYR M O 1 ATOM 264 C CB . TYR A 1 38 ? 56.562 118.183 60.055 1.00 7.44 ? 38 TYR M CB 1 ATOM 265 C CG . TYR A 1 38 ? 57.845 118.699 59.475 1.00 6.32 ? 38 TYR M CG 1 ATOM 266 C CD1 . TYR A 1 38 ? 59.042 118.281 59.991 1.00 6.64 ? 38 TYR M CD1 1 ATOM 267 C CD2 . TYR A 1 38 ? 57.880 119.557 58.456 1.00 7.12 ? 38 TYR M CD2 1 ATOM 268 C CE1 . TYR A 1 38 ? 60.271 118.884 59.587 1.00 7.14 ? 38 TYR M CE1 1 ATOM 269 C CE2 . TYR A 1 38 ? 59.049 120.119 58.004 1.00 9.01 ? 38 TYR M CE2 1 ATOM 270 C CZ . TYR A 1 38 ? 60.222 119.767 58.566 1.00 7.54 ? 38 TYR M CZ 1 ATOM 271 O OH . TYR A 1 38 ? 61.414 120.369 58.157 1.00 8.12 ? 38 TYR M OH 1 ATOM 272 N N . GLN A 1 39 ? 54.888 120.735 60.885 1.00 7.70 ? 39 GLN M N 1 ATOM 273 C CA . GLN A 1 39 ? 54.631 122.108 60.530 1.00 7.86 ? 39 GLN M CA 1 ATOM 274 C C . GLN A 1 39 ? 54.646 123.076 61.684 1.00 6.99 ? 39 GLN M C 1 ATOM 275 O O . GLN A 1 39 ? 54.910 124.306 61.444 1.00 10.17 ? 39 GLN M O 1 ATOM 276 C CB . GLN A 1 39 ? 53.324 122.234 59.747 1.00 8.08 ? 39 GLN M CB 1 ATOM 277 C CG . GLN A 1 39 ? 53.342 121.408 58.500 1.00 8.26 ? 39 GLN M CG 1 ATOM 278 C CD . GLN A 1 39 ? 52.076 121.497 57.685 1.00 12.17 ? 39 GLN M CD 1 ATOM 279 O OE1 . GLN A 1 39 ? 51.165 120.690 57.823 1.00 11.29 ? 39 GLN M OE1 1 ATOM 280 N NE2 . GLN A 1 39 ? 52.006 122.514 56.833 1.00 11.01 ? 39 GLN M NE2 1 ATOM 281 N N . ILE A 1 40 ? 54.400 122.593 62.920 1.00 6.55 ? 40 ILE M N 1 ATOM 282 C CA . ILE A 1 40 ? 54.264 123.460 64.099 1.00 7.51 ? 40 ILE M CA 1 ATOM 283 C C . ILE A 1 40 ? 55.216 123.233 65.200 1.00 8.11 ? 40 ILE M C 1 ATOM 284 O O . ILE A 1 40 ? 55.441 124.187 65.985 1.00 8.23 ? 40 ILE M O 1 ATOM 285 C CB . ILE A 1 40 ? 52.814 123.491 64.674 1.00 6.91 ? 40 ILE M CB 1 ATOM 286 C CG1 . ILE A 1 40 ? 52.450 122.193 65.389 1.00 9.56 ? 40 ILE M CG1 1 ATOM 287 C CG2 . ILE A 1 40 ? 51.820 123.848 63.506 1.00 10.83 ? 40 ILE M CG2 1 ATOM 288 C CD1 . ILE A 1 40 ? 51.118 122.246 66.123 1.00 9.19 ? 40 ILE M CD1 1 ATOM 289 N N . GLU A 1 41 ? 55.749 122.014 65.440 1.00 8.14 ? 41 GLU M N 1 ATOM 290 C CA . GLU A 1 41 ? 56.364 121.771 66.737 1.00 6.81 ? 41 GLU M CA 1 ATOM 291 C C . GLU A 1 41 ? 57.797 122.301 66.854 1.00 8.50 ? 41 GLU M C 1 ATOM 292 O O . GLU A 1 41 ? 58.160 122.855 67.900 1.00 9.33 ? 41 GLU M O 1 ATOM 293 C CB . GLU A 1 41 ? 56.386 120.301 67.101 1.00 8.82 ? 41 GLU M CB 1 ATOM 294 C CG . GLU A 1 41 ? 55.034 119.613 67.241 1.00 8.89 ? 41 GLU M CG 1 ATOM 295 C CD . GLU A 1 41 ? 55.114 118.138 67.526 1.00 9.57 ? 41 GLU M CD 1 ATOM 296 O OE1 . GLU A 1 41 ? 56.195 117.541 67.398 1.00 9.48 ? 41 GLU M OE1 1 ATOM 297 O OE2 . GLU A 1 41 ? 54.034 117.614 67.911 1.00 8.81 ? 41 GLU M OE2 1 ATOM 298 N N . GLY A 1 42 ? 58.576 122.004 65.857 1.00 8.81 ? 42 GLY M N 1 ATOM 299 C CA . GLY A 1 42 ? 60.058 122.178 65.917 1.00 9.08 ? 42 GLY M CA 1 ATOM 300 C C . GLY A 1 42 ? 60.727 120.848 66.190 1.00 10.43 ? 42 GLY M C 1 ATOM 301 O O . GLY A 1 42 ? 60.116 119.907 66.712 1.00 10.15 ? 42 GLY M O 1 ATOM 302 N N . THR A 1 43 ? 62.046 120.756 65.975 1.00 8.07 ? 43 THR M N 1 ATOM 303 C CA . THR A 1 43 ? 62.758 119.537 66.204 1.00 10.12 ? 43 THR M CA 1 ATOM 304 C C . THR A 1 43 ? 63.196 119.311 67.635 1.00 8.40 ? 43 THR M C 1 ATOM 305 O O . THR A 1 43 ? 63.557 118.209 67.970 1.00 9.37 ? 43 THR M O 1 ATOM 306 C CB . THR A 1 43 ? 64.060 119.544 65.336 1.00 10.21 ? 43 THR M CB 1 ATOM 307 O OG1 . THR A 1 43 ? 64.801 120.748 65.641 1.00 12.83 ? 43 THR M OG1 1 ATOM 308 C CG2 . THR A 1 43 ? 63.773 119.468 63.795 1.00 11.38 ? 43 THR M CG2 1 ATOM 309 N N . ILE A 1 44 ? 63.150 120.308 68.495 1.00 8.66 ? 44 ILE M N 1 ATOM 310 C CA . ILE A 1 44 ? 63.497 120.166 69.910 1.00 9.55 ? 44 ILE M CA 1 ATOM 311 C C . ILE A 1 44 ? 62.756 118.980 70.496 1.00 8.35 ? 44 ILE M C 1 ATOM 312 O O . ILE A 1 44 ? 61.503 118.884 70.301 1.00 9.66 ? 44 ILE M O 1 ATOM 313 C CB . ILE A 1 44 ? 63.225 121.409 70.730 1.00 10.07 ? 44 ILE M CB 1 ATOM 314 C CG1 . ILE A 1 44 ? 63.657 121.210 72.145 1.00 13.79 ? 44 ILE M CG1 1 ATOM 315 C CG2 . ILE A 1 44 ? 61.759 121.965 70.501 1.00 13.46 ? 44 ILE M CG2 1 ATOM 316 C CD1 . ILE A 1 44 ? 63.790 122.517 72.978 1.00 17.50 ? 44 ILE M CD1 1 ATOM 317 N N . GLY A 1 45 ? 63.432 118.052 71.170 1.00 7.74 ? 45 GLY M N 1 ATOM 318 C CA . GLY A 1 45 ? 62.818 117.016 71.875 1.00 8.42 ? 45 GLY M CA 1 ATOM 319 C C . GLY A 1 45 ? 62.387 115.792 71.043 1.00 8.50 ? 45 GLY M C 1 ATOM 320 O O . GLY A 1 45 ? 61.806 114.865 71.599 1.00 9.42 ? 45 GLY M O 1 ATOM 321 N N . ARG A 1 46 ? 62.707 115.768 69.764 1.00 7.11 ? 46 ARG M N 1 ATOM 322 C CA . ARG A 1 46 ? 62.387 114.613 68.930 1.00 7.52 ? 46 ARG M CA 1 ATOM 323 C C . ARG A 1 46 ? 63.552 114.149 68.074 1.00 7.73 ? 46 ARG M C 1 ATOM 324 O O . ARG A 1 46 ? 64.542 114.898 67.904 1.00 8.28 ? 46 ARG M O 1 ATOM 325 C CB . ARG A 1 46 ? 61.160 114.918 68.022 1.00 8.97 ? 46 ARG M CB 1 ATOM 326 C CG . ARG A 1 46 ? 61.278 116.049 67.064 1.00 7.94 ? 46 ARG M CG 1 ATOM 327 C CD . ARG A 1 46 ? 60.181 116.001 66.036 1.00 8.60 ? 46 ARG M CD 1 ATOM 328 N NE . ARG A 1 46 ? 60.169 117.053 65.034 1.00 8.22 ? 46 ARG M NE 1 ATOM 329 C CZ . ARG A 1 46 ? 60.973 117.046 63.961 1.00 10.47 ? 46 ARG M CZ 1 ATOM 330 N NH1 . ARG A 1 46 ? 61.868 116.087 63.753 1.00 9.60 ? 46 ARG M NH1 1 ATOM 331 N NH2 . ARG A 1 46 ? 60.763 117.999 63.029 1.00 9.24 ? 46 ARG M NH2 1 ATOM 332 N N . GLY A 1 47 ? 63.395 112.952 67.544 1.00 7.83 ? 47 GLY M N 1 ATOM 333 C CA . GLY A 1 47 ? 64.296 112.388 66.559 1.00 7.53 ? 47 GLY M CA 1 ATOM 334 C C . GLY A 1 47 ? 64.062 113.058 65.218 1.00 8.64 ? 47 GLY M C 1 ATOM 335 O O . GLY A 1 47 ? 63.219 113.889 65.004 1.00 9.50 ? 47 GLY M O 1 ATOM 336 N N . LEU A 1 48 ? 64.877 112.634 64.232 1.00 8.81 ? 48 LEU M N 1 ATOM 337 C CA . LEU A 1 48 ? 64.773 113.220 62.889 1.00 8.40 ? 48 LEU M CA 1 ATOM 338 C C . LEU A 1 48 ? 63.951 112.326 62.014 1.00 8.42 ? 48 LEU M C 1 ATOM 339 O O . LEU A 1 48 ? 63.967 111.119 62.062 1.00 9.20 ? 48 LEU M O 1 ATOM 340 C CB . LEU A 1 48 ? 66.189 113.227 62.243 1.00 11.07 ? 48 LEU M CB 1 ATOM 341 C CG . LEU A 1 48 ? 67.183 114.109 62.962 1.00 12.70 ? 48 LEU M CG 1 ATOM 342 C CD1 . LEU A 1 48 ? 68.671 113.678 62.352 1.00 14.45 ? 48 LEU M CD1 1 ATOM 343 C CD2 . LEU A 1 48 ? 66.851 115.545 62.775 1.00 16.84 ? 48 LEU M CD2 1 ATOM 344 N N . ASN A 1 49 ? 63.182 113.008 61.175 1.00 7.24 ? 49 ASN M N 1 ATOM 345 C CA . ASN A 1 49 ? 62.278 112.355 60.215 1.00 6.67 ? 49 ASN M CA 1 ATOM 346 C C . ASN A 1 49 ? 62.618 112.732 58.785 1.00 7.24 ? 49 ASN M C 1 ATOM 347 O O . ASN A 1 49 ? 63.488 113.548 58.496 1.00 7.78 ? 49 ASN M O 1 ATOM 348 C CB . ASN A 1 49 ? 60.821 112.630 60.613 1.00 6.72 ? 49 ASN M CB 1 ATOM 349 C CG . ASN A 1 49 ? 60.476 114.064 60.552 1.00 8.40 ? 49 ASN M CG 1 ATOM 350 O OD1 . ASN A 1 49 ? 60.649 114.752 59.565 1.00 8.58 ? 49 ASN M OD1 1 ATOM 351 N ND2 . ASN A 1 49 ? 59.873 114.555 61.661 1.00 8.94 ? 49 ASN M ND2 1 ATOM 352 N N . ILE A 1 50 ? 61.846 112.154 57.816 1.00 6.73 ? 50 ILE M N 1 ATOM 353 C CA . ILE A 1 50 ? 62.172 112.357 56.423 1.00 7.44 ? 50 ILE M CA 1 ATOM 354 C C . ILE A 1 50 ? 61.901 113.779 55.937 1.00 6.76 ? 50 ILE M C 1 ATOM 355 O O . ILE A 1 50 ? 62.403 114.163 54.913 1.00 7.84 ? 50 ILE M O 1 ATOM 356 C CB . ILE A 1 50 ? 61.515 111.341 55.455 1.00 6.37 ? 50 ILE M CB 1 ATOM 357 C CG1 . ILE A 1 50 ? 59.977 111.452 55.525 1.00 8.32 ? 50 ILE M CG1 1 ATOM 358 C CG2 . ILE A 1 50 ? 61.978 109.897 55.787 1.00 8.71 ? 50 ILE M CG2 1 ATOM 359 C CD1 . ILE A 1 50 ? 59.256 110.505 54.374 1.00 9.07 ? 50 ILE M CD1 1 ATOM 360 N N . TRP A 1 51 ? 61.046 114.518 56.630 1.00 6.49 ? 51 TRP M N 1 ATOM 361 C CA . TRP A 1 51 ? 60.892 115.928 56.294 1.00 6.39 ? 51 TRP M CA 1 ATOM 362 C C . TRP A 1 51 ? 62.080 116.725 56.767 1.00 7.72 ? 51 TRP M C 1 ATOM 363 O O . TRP A 1 51 ? 62.490 117.619 56.009 1.00 9.13 ? 51 TRP M O 1 ATOM 364 C CB . TRP A 1 51 ? 59.532 116.471 56.740 1.00 8.90 ? 51 TRP M CB 1 ATOM 365 C CG . TRP A 1 51 ? 58.480 116.246 55.617 1.00 6.69 ? 51 TRP M CG 1 ATOM 366 C CD1 . TRP A 1 51 ? 57.605 115.204 55.443 1.00 7.93 ? 51 TRP M CD1 1 ATOM 367 C CD2 . TRP A 1 51 ? 58.361 117.058 54.448 1.00 6.78 ? 51 TRP M CD2 1 ATOM 368 N NE1 . TRP A 1 51 ? 56.967 115.338 54.260 1.00 7.47 ? 51 TRP M NE1 1 ATOM 369 C CE2 . TRP A 1 51 ? 57.367 116.480 53.636 1.00 7.18 ? 51 TRP M CE2 1 ATOM 370 C CE3 . TRP A 1 51 ? 58.942 118.265 54.021 1.00 8.77 ? 51 TRP M CE3 1 ATOM 371 C CZ2 . TRP A 1 51 ? 56.975 117.063 52.433 1.00 7.65 ? 51 TRP M CZ2 1 ATOM 372 C CZ3 . TRP A 1 51 ? 58.588 118.782 52.828 1.00 8.38 ? 51 TRP M CZ3 1 ATOM 373 C CH2 . TRP A 1 51 ? 57.646 118.175 52.029 1.00 8.28 ? 51 TRP M CH2 1 ATOM 374 N N . ASP A 1 52 ? 62.670 116.413 57.945 1.00 6.68 ? 52 ASP M N 1 ATOM 375 C CA . ASP A 1 52 ? 63.941 117.031 58.265 1.00 7.14 ? 52 ASP M CA 1 ATOM 376 C C . ASP A 1 52 ? 64.933 116.637 57.160 1.00 6.62 ? 52 ASP M C 1 ATOM 377 O O . ASP A 1 52 ? 65.686 117.486 56.636 1.00 8.00 ? 52 ASP M O 1 ATOM 378 C CB . ASP A 1 52 ? 64.445 116.478 59.610 1.00 7.29 ? 52 ASP M CB 1 ATOM 379 C CG . ASP A 1 52 ? 63.497 116.699 60.727 1.00 7.95 ? 52 ASP M CG 1 ATOM 380 O OD1 . ASP A 1 52 ? 63.079 117.826 60.999 1.00 9.62 ? 52 ASP M OD1 1 ATOM 381 O OD2 . ASP A 1 52 ? 63.217 115.726 61.478 1.00 10.50 ? 52 ASP M OD2 1 ATOM 382 N N . GLY A 1 53 ? 65.002 115.370 56.793 1.00 7.14 ? 53 GLY M N 1 ATOM 383 C CA . GLY A 1 53 ? 65.991 114.912 55.856 1.00 6.74 ? 53 GLY M CA 1 ATOM 384 C C . GLY A 1 53 ? 65.860 115.538 54.516 1.00 7.69 ? 53 GLY M C 1 ATOM 385 O O . GLY A 1 53 ? 66.851 116.013 53.918 1.00 9.57 ? 53 GLY M O 1 ATOM 386 N N . PHE A 1 54 ? 64.634 115.605 54.011 1.00 6.49 ? 54 PHE M N 1 ATOM 387 C CA . PHE A 1 54 ? 64.374 116.172 52.679 1.00 6.96 ? 54 PHE M CA 1 ATOM 388 C C . PHE A 1 54 ? 64.632 117.670 52.661 1.00 7.48 ? 54 PHE M C 1 ATOM 389 O O . PHE A 1 54 ? 65.289 118.138 51.718 1.00 8.14 ? 54 PHE M O 1 ATOM 390 C CB . PHE A 1 54 ? 62.900 115.884 52.323 1.00 7.21 ? 54 PHE M CB 1 ATOM 391 C CG . PHE A 1 54 ? 62.396 116.425 51.036 1.00 7.76 ? 54 PHE M CG 1 ATOM 392 C CD1 . PHE A 1 54 ? 62.755 115.799 49.854 1.00 8.60 ? 54 PHE M CD1 1 ATOM 393 C CD2 . PHE A 1 54 ? 61.533 117.473 50.955 1.00 9.27 ? 54 PHE M CD2 1 ATOM 394 C CE1 . PHE A 1 54 ? 62.301 116.272 48.657 1.00 11.28 ? 54 PHE M CE1 1 ATOM 395 C CE2 . PHE A 1 54 ? 61.076 117.947 49.737 1.00 9.04 ? 54 PHE M CE2 1 ATOM 396 C CZ . PHE A 1 54 ? 61.451 117.320 48.596 1.00 7.97 ? 54 PHE M CZ 1 ATOM 397 N N . THR A 1 55 ? 64.120 118.443 53.617 1.00 7.36 ? 55 THR M N 1 ATOM 398 C CA . THR A 1 55 ? 64.348 119.895 53.625 1.00 6.71 ? 55 THR M CA 1 ATOM 399 C C . THR A 1 55 ? 65.798 120.216 53.772 1.00 8.99 ? 55 THR M C 1 ATOM 400 O O . THR A 1 55 ? 66.202 121.339 53.323 1.00 7.67 ? 55 THR M O 1 ATOM 401 C CB . THR A 1 55 ? 63.533 120.563 54.724 1.00 7.52 ? 55 THR M CB 1 ATOM 402 O OG1 . THR A 1 55 ? 63.899 120.065 55.982 1.00 8.41 ? 55 THR M OG1 1 ATOM 403 C CG2 . THR A 1 55 ? 62.017 120.373 54.460 1.00 8.90 ? 55 THR M CG2 1 ATOM 404 N N . HIS A 1 56 ? 66.639 119.387 54.381 1.00 7.33 ? 56 HIS M N 1 ATOM 405 C CA . HIS A 1 56 ? 68.011 119.714 54.587 1.00 8.03 ? 56 HIS M CA 1 ATOM 406 C C . HIS A 1 56 ? 68.899 119.224 53.404 1.00 9.12 ? 56 HIS M C 1 ATOM 407 O O . HIS A 1 56 ? 69.887 119.882 53.072 1.00 9.32 ? 56 HIS M O 1 ATOM 408 C CB . HIS A 1 56 ? 68.446 119.092 55.927 1.00 7.47 ? 56 HIS M CB 1 ATOM 409 C CG . HIS A 1 56 ? 67.979 119.845 57.129 1.00 9.86 ? 56 HIS M CG 1 ATOM 410 N ND1 . HIS A 1 56 ? 66.602 120.039 57.368 1.00 8.94 ? 56 HIS M ND1 1 ATOM 411 C CD2 . HIS A 1 56 ? 68.641 120.595 58.057 1.00 9.21 ? 56 HIS M CD2 1 ATOM 412 C CE1 . HIS A 1 56 ? 66.511 120.793 58.485 1.00 9.37 ? 56 HIS M CE1 1 ATOM 413 N NE2 . HIS A 1 56 ? 67.722 121.119 58.965 1.00 7.42 ? 56 HIS M NE2 1 ATOM 414 N N . ARG A 1 57 ? 68.555 118.099 52.779 1.00 6.81 ? 57 ARG M N 1 ATOM 415 C CA . ARG A 1 57 ? 69.318 117.529 51.662 1.00 7.53 ? 57 ARG M CA 1 ATOM 416 C C . ARG A 1 57 ? 69.011 118.353 50.363 1.00 9.66 ? 57 ARG M C 1 ATOM 417 O O . ARG A 1 57 ? 69.893 118.509 49.542 1.00 8.77 ? 57 ARG M O 1 ATOM 418 C CB . ARG A 1 57 ? 68.983 116.071 51.456 1.00 8.20 ? 57 ARG M CB 1 ATOM 419 C CG . ARG A 1 57 ? 69.801 115.454 50.357 1.00 9.27 ? 57 ARG M CG 1 ATOM 420 C CD . ARG A 1 57 ? 69.720 113.965 50.438 1.00 9.59 ? 57 ARG M CD 1 ATOM 421 N NE . ARG A 1 57 ? 70.566 113.313 49.459 1.00 10.54 ? 57 ARG M NE 1 ATOM 422 C CZ . ARG A 1 57 ? 70.689 111.991 49.286 1.00 11.54 ? 57 ARG M CZ 1 ATOM 423 N NH1 . ARG A 1 57 ? 70.061 111.132 50.064 1.00 11.78 ? 57 ARG M NH1 1 ATOM 424 N NH2 . ARG A 1 57 ? 71.537 111.553 48.335 1.00 11.89 ? 57 ARG M NH2 1 ATOM 425 N N . TYR A 1 58 ? 67.757 118.798 50.255 1.00 8.78 ? 58 TYR M N 1 ATOM 426 C CA . TYR A 1 58 ? 67.215 119.491 49.067 1.00 8.77 ? 58 TYR M CA 1 ATOM 427 C C . TYR A 1 58 ? 66.607 120.826 49.483 1.00 9.59 ? 58 TYR M C 1 ATOM 428 O O . TYR A 1 58 ? 65.366 120.997 49.398 1.00 11.12 ? 58 TYR M O 1 ATOM 429 C CB . TYR A 1 58 ? 66.187 118.601 48.361 1.00 9.31 ? 58 TYR M CB 1 ATOM 430 C CG . TYR A 1 58 ? 66.644 117.189 48.022 1.00 8.28 ? 58 TYR M CG 1 ATOM 431 C CD1 . TYR A 1 58 ? 67.511 116.964 46.970 1.00 10.84 ? 58 TYR M CD1 1 ATOM 432 C CD2 . TYR A 1 58 ? 66.291 116.065 48.744 1.00 9.67 ? 58 TYR M CD2 1 ATOM 433 C CE1 . TYR A 1 58 ? 67.951 115.755 46.607 1.00 12.79 ? 58 TYR M CE1 1 ATOM 434 C CE2 . TYR A 1 58 ? 66.733 114.789 48.390 1.00 9.87 ? 58 TYR M CE2 1 ATOM 435 C CZ . TYR A 1 58 ? 67.585 114.636 47.369 1.00 10.21 ? 58 TYR M CZ 1 ATOM 436 O OH . TYR A 1 58 ? 67.994 113.344 47.061 1.00 16.07 ? 58 TYR M OH 1 ATOM 437 N N . PRO A 1 59 ? 67.446 121.761 49.955 1.00 10.76 ? 59 PRO M N 1 ATOM 438 C CA . PRO A 1 59 ? 66.849 122.972 50.467 1.00 10.98 ? 59 PRO M CA 1 ATOM 439 C C . PRO A 1 59 ? 66.017 123.758 49.469 1.00 11.72 ? 59 PRO M C 1 ATOM 440 O O . PRO A 1 59 ? 65.022 124.363 49.904 1.00 13.09 ? 59 PRO M O 1 ATOM 441 C CB . PRO A 1 59 ? 68.030 123.787 51.001 1.00 16.25 ? 59 PRO M CB 1 ATOM 442 C CG . PRO A 1 59 ? 69.197 123.113 50.538 1.00 17.57 ? 59 PRO M CG 1 ATOM 443 C CD . PRO A 1 59 ? 68.908 121.687 50.132 1.00 12.35 ? 59 PRO M CD 1 ATOM 444 N N . ASN A 1 60 ? 66.340 123.697 48.202 1.00 12.94 ? 60 ASN M N 1 ATOM 445 C CA . ASN A 1 60 ? 65.453 124.374 47.256 1.00 14.54 ? 60 ASN M CA 1 ATOM 446 C C . ASN A 1 60 ? 64.112 123.748 47.014 1.00 15.35 ? 60 ASN M C 1 ATOM 447 O O . ASN A 1 60 ? 63.173 124.423 46.521 1.00 16.99 ? 60 ASN M O 1 ATOM 448 C CB . ASN A 1 60 ? 66.206 124.666 45.989 1.00 17.81 ? 60 ASN M CB 1 ATOM 449 C CG . ASN A 1 60 ? 66.454 123.519 45.133 1.00 20.70 ? 60 ASN M CG 1 ATOM 450 O OD1 . ASN A 1 60 ? 66.128 122.384 45.360 1.00 27.43 ? 60 ASN M OD1 1 ATOM 451 N ND2 . ASN A 1 60 ? 67.197 123.863 44.045 1.00 30.21 ? 60 ASN M ND2 1 ATOM 452 N N . LYS A 1 61 ? 63.904 122.554 47.540 1.00 12.01 ? 61 LYS M N 1 ATOM 453 C CA . LYS A 1 61 ? 62.629 121.876 47.485 1.00 11.16 ? 61 LYS M CA 1 ATOM 454 C C . LYS A 1 61 ? 61.815 122.119 48.807 1.00 12.95 ? 61 LYS M C 1 ATOM 455 O O . LYS A 1 61 ? 60.638 121.810 48.885 1.00 15.26 ? 61 LYS M O 1 ATOM 456 C CB . LYS A 1 61 ? 62.763 120.360 47.235 1.00 14.47 ? 61 LYS M CB 1 ATOM 457 C CG . LYS A 1 61 ? 63.279 120.031 45.808 1.00 16.36 ? 61 LYS M CG 1 ATOM 458 C CD . LYS A 1 61 ? 63.308 118.462 45.667 1.00 18.02 ? 61 LYS M CD 1 ATOM 459 C CE . LYS A 1 61 ? 63.821 118.054 44.438 1.00 26.77 ? 61 LYS M CE 1 ATOM 460 N NZ . LYS A 1 61 ? 63.399 116.683 44.298 1.00 17.31 ? 61 LYS M NZ 1 ATOM 461 N N . SER A 1 62 ? 62.525 122.649 49.814 1.00 13.74 ? 62 SER M N 1 ATOM 462 C CA . SER A 1 62 ? 61.825 122.908 51.129 1.00 14.56 ? 62 SER M CA 1 ATOM 463 C C . SER A 1 62 ? 60.883 124.068 50.967 1.00 12.19 ? 62 SER M C 1 ATOM 464 O O . SER A 1 62 ? 59.850 124.173 51.690 1.00 14.14 ? 62 SER M O 1 ATOM 465 C CB A SER A 1 62 ? 62.839 123.123 52.242 0.70 12.67 ? 62 SER M CB 1 ATOM 466 C CB B SER A 1 62 ? 62.755 123.156 52.292 0.30 13.60 ? 62 SER M CB 1 ATOM 467 O OG A SER A 1 62 ? 63.554 124.377 52.163 0.70 14.78 ? 62 SER M OG 1 ATOM 468 O OG B SER A 1 62 ? 61.969 123.223 53.482 0.30 14.36 ? 62 SER M OG 1 ATOM 469 N N . GLY A 1 63 ? 61.283 125.072 50.153 1.00 12.43 ? 63 GLY M N 1 ATOM 470 C CA . GLY A 1 63 ? 60.533 126.290 49.953 1.00 13.64 ? 63 GLY M CA 1 ATOM 471 C C . GLY A 1 63 ? 61.441 127.250 49.189 1.00 13.35 ? 63 GLY M C 1 ATOM 472 O O . GLY A 1 63 ? 62.643 127.112 49.208 1.00 13.95 ? 63 GLY M O 1 ATOM 473 N N . PRO A 1 64 ? 60.821 128.283 48.598 1.00 14.24 ? 64 PRO M N 1 ATOM 474 C CA . PRO A 1 64 ? 61.647 129.245 47.880 1.00 15.67 ? 64 PRO M CA 1 ATOM 475 C C . PRO A 1 64 ? 62.588 129.941 48.778 1.00 17.10 ? 64 PRO M C 1 ATOM 476 O O . PRO A 1 64 ? 63.666 130.394 48.295 1.00 19.03 ? 64 PRO M O 1 ATOM 477 C CB . PRO A 1 64 ? 60.610 130.195 47.276 1.00 16.08 ? 64 PRO M CB 1 ATOM 478 C CG . PRO A 1 64 ? 59.425 129.427 47.081 1.00 18.69 ? 64 PRO M CG 1 ATOM 479 C CD . PRO A 1 64 ? 59.367 128.447 48.268 1.00 16.05 ? 64 PRO M CD 1 ATOM 480 N N . ASP A 1 65 ? 62.235 130.086 50.044 1.00 14.39 ? 65 ASP M N 1 ATOM 481 C CA . ASP A 1 65 ? 62.990 130.668 51.113 1.00 15.42 ? 65 ASP M CA 1 ATOM 482 C C . ASP A 1 65 ? 63.906 129.671 51.851 1.00 12.97 ? 65 ASP M C 1 ATOM 483 O O . ASP A 1 65 ? 64.643 130.072 52.784 1.00 14.52 ? 65 ASP M O 1 ATOM 484 C CB . ASP A 1 65 ? 62.063 131.378 52.114 1.00 17.08 ? 65 ASP M CB 1 ATOM 485 C CG . ASP A 1 65 ? 61.099 130.373 52.821 1.00 15.28 ? 65 ASP M CG 1 ATOM 486 O OD1 . ASP A 1 65 ? 61.079 129.195 52.418 1.00 13.22 ? 65 ASP M OD1 1 ATOM 487 O OD2 . ASP A 1 65 ? 60.442 130.880 53.773 1.00 17.57 ? 65 ASP M OD2 1 ATOM 488 N N . HIS A 1 66 ? 63.986 128.423 51.365 1.00 12.26 ? 66 HIS M N 1 ATOM 489 C CA . HIS A 1 66 ? 64.720 127.404 52.057 1.00 13.66 ? 66 HIS M CA 1 ATOM 490 C C . HIS A 1 66 ? 64.272 127.181 53.477 1.00 15.00 ? 66 HIS M C 1 ATOM 491 O O . HIS A 1 66 ? 64.999 126.553 54.247 1.00 15.75 ? 66 HIS M O 1 ATOM 492 C CB . HIS A 1 66 ? 66.267 127.564 51.949 1.00 15.23 ? 66 HIS M CB 1 ATOM 493 C CG . HIS A 1 66 ? 66.768 127.567 50.581 1.00 16.33 ? 66 HIS M CG 1 ATOM 494 N ND1 . HIS A 1 66 ? 68.132 127.536 50.312 1.00 22.93 ? 66 HIS M ND1 1 ATOM 495 C CD2 . HIS A 1 66 ? 66.141 127.628 49.383 1.00 17.16 ? 66 HIS M CD2 1 ATOM 496 C CE1 . HIS A 1 66 ? 68.284 127.489 48.994 1.00 25.96 ? 66 HIS M CE1 1 ATOM 497 N NE2 . HIS A 1 66 ? 67.110 127.712 48.418 1.00 23.16 ? 66 HIS M NE2 1 ATOM 498 N N . GLY A 1 67 ? 63.072 127.594 53.841 1.00 14.84 ? 67 GLY M N 1 ATOM 499 C CA . GLY A 1 67 ? 62.580 127.410 55.163 1.00 13.41 ? 67 GLY M CA 1 ATOM 500 C C . GLY A 1 67 ? 62.236 125.985 55.449 1.00 12.10 ? 67 GLY M C 1 ATOM 501 O O . GLY A 1 67 ? 62.015 125.165 54.550 1.00 15.23 ? 67 GLY M O 1 ATOM 502 N N . ASN A 1 68 ? 62.257 125.628 56.750 1.00 11.18 ? 68 ASN M N 1 ATOM 503 C CA . ASN A 1 68 ? 61.981 124.267 57.193 1.00 10.33 ? 68 ASN M CA 1 ATOM 504 C C . ASN A 1 68 ? 61.358 124.257 58.542 1.00 11.24 ? 68 ASN M C 1 ATOM 505 O O . ASN A 1 68 ? 61.051 125.313 59.084 1.00 10.81 ? 68 ASN M O 1 ATOM 506 C CB . ASN A 1 68 ? 63.286 123.399 57.170 1.00 10.06 ? 68 ASN M CB 1 ATOM 507 C CG . ASN A 1 68 ? 64.340 123.928 58.044 1.00 12.31 ? 68 ASN M CG 1 ATOM 508 O OD1 . ASN A 1 68 ? 64.076 124.312 59.153 1.00 10.43 ? 68 ASN M OD1 1 ATOM 509 N ND2 . ASN A 1 68 ? 65.593 124.106 57.502 1.00 11.34 ? 68 ASN M ND2 1 ATOM 510 N N . GLY A 1 69 ? 61.047 123.062 59.060 1.00 8.88 ? 69 GLY M N 1 ATOM 511 C CA . GLY A 1 69 ? 60.364 122.926 60.328 1.00 9.21 ? 69 GLY M CA 1 ATOM 512 C C . GLY A 1 69 ? 61.258 122.877 61.560 1.00 10.14 ? 69 GLY M C 1 ATOM 513 O O . GLY A 1 69 ? 60.852 122.410 62.614 1.00 10.80 ? 69 GLY M O 1 ATOM 514 N N . ASP A 1 70 ? 62.518 123.369 61.464 1.00 9.17 ? 70 ASP M N 1 ATOM 515 C CA . ASP A 1 70 ? 63.379 123.272 62.613 1.00 10.42 ? 70 ASP M CA 1 ATOM 516 C C . ASP A 1 70 ? 62.883 123.938 63.905 1.00 10.44 ? 70 ASP M C 1 ATOM 517 O O . ASP A 1 70 ? 62.949 123.364 64.986 1.00 10.98 ? 70 ASP M O 1 ATOM 518 C CB . ASP A 1 70 ? 64.748 123.847 62.281 1.00 9.03 ? 70 ASP M CB 1 ATOM 519 C CG . ASP A 1 70 ? 65.658 122.972 61.434 1.00 8.51 ? 70 ASP M CG 1 ATOM 520 O OD1 . ASP A 1 70 ? 65.257 121.827 61.131 1.00 9.93 ? 70 ASP M OD1 1 ATOM 521 O OD2 . ASP A 1 70 ? 66.818 123.497 61.153 1.00 9.83 ? 70 ASP M OD2 1 ATOM 522 N N . THR A 1 71 ? 62.358 125.138 63.770 1.00 10.69 ? 71 THR M N 1 ATOM 523 C CA . THR A 1 71 ? 61.758 125.867 64.903 1.00 10.87 ? 71 THR M CA 1 ATOM 524 C C . THR A 1 71 ? 60.322 126.192 64.634 1.00 10.90 ? 71 THR M C 1 ATOM 525 O O . THR A 1 71 ? 59.477 126.028 65.544 1.00 11.19 ? 71 THR M O 1 ATOM 526 C CB . THR A 1 71 ? 62.586 127.064 65.222 1.00 12.91 ? 71 THR M CB 1 ATOM 527 O OG1 . THR A 1 71 ? 62.752 127.938 64.112 1.00 14.45 ? 71 THR M OG1 1 ATOM 528 C CG2 . THR A 1 71 ? 63.953 126.670 65.642 1.00 14.99 ? 71 THR M CG2 1 ATOM 529 N N . THR A 1 72 ? 59.984 126.669 63.432 1.00 10.55 ? 72 THR M N 1 ATOM 530 C CA . THR A 1 72 ? 58.644 127.015 63.065 1.00 11.23 ? 72 THR M CA 1 ATOM 531 C C . THR A 1 72 ? 57.920 127.826 64.175 1.00 11.28 ? 72 THR M C 1 ATOM 532 O O . THR A 1 72 ? 58.576 128.706 64.737 1.00 12.31 ? 72 THR M O 1 ATOM 533 C CB . THR A 1 72 ? 57.911 125.814 62.437 1.00 11.84 ? 72 THR M CB 1 ATOM 534 O OG1 . THR A 1 72 ? 56.581 126.263 62.031 1.00 13.28 ? 72 THR M OG1 1 ATOM 535 C CG2 . THR A 1 72 ? 57.848 124.591 63.341 1.00 12.92 ? 72 THR M CG2 1 ATOM 536 N N . CYS A 1 73 ? 56.648 127.564 64.448 1.00 12.98 ? 73 CYS M N 1 ATOM 537 C CA . CYS A 1 73 ? 55.968 128.327 65.476 1.00 13.17 ? 73 CYS M CA 1 ATOM 538 C C . CYS A 1 73 ? 56.235 127.843 66.876 1.00 12.23 ? 73 CYS M C 1 ATOM 539 O O . CYS A 1 73 ? 55.638 128.345 67.834 1.00 14.00 ? 73 CYS M O 1 ATOM 540 C CB . CYS A 1 73 ? 54.557 128.578 65.144 1.00 17.87 ? 73 CYS M CB 1 ATOM 541 S SG . CYS A 1 73 ? 53.722 127.064 64.761 1.00 21.67 ? 73 CYS M SG 1 ATOM 542 N N . ASP A 1 74 ? 57.136 126.877 67.055 1.00 10.99 ? 74 ASP M N 1 ATOM 543 C CA . ASP A 1 74 ? 57.554 126.393 68.329 1.00 12.37 ? 74 ASP M CA 1 ATOM 544 C C . ASP A 1 74 ? 56.349 125.994 69.204 1.00 14.38 ? 74 ASP M C 1 ATOM 545 O O . ASP A 1 74 ? 56.299 126.323 70.367 1.00 13.32 ? 74 ASP M O 1 ATOM 546 C CB . ASP A 1 74 ? 58.499 127.400 69.022 1.00 10.96 ? 74 ASP M CB 1 ATOM 547 C CG . ASP A 1 74 ? 59.267 126.778 70.143 1.00 17.06 ? 74 ASP M CG 1 ATOM 548 O OD1 . ASP A 1 74 ? 59.179 125.581 70.449 1.00 17.48 ? 74 ASP M OD1 1 ATOM 549 O OD2 . ASP A 1 74 ? 59.960 127.618 70.833 1.00 22.04 ? 74 ASP M OD2 1 ATOM 550 N N . SER A 1 75 ? 55.480 125.157 68.655 1.00 11.14 ? 75 SER M N 1 ATOM 551 C CA . SER A 1 75 ? 54.404 124.618 69.477 1.00 9.80 ? 75 SER M CA 1 ATOM 552 C C . SER A 1 75 ? 54.895 123.607 70.460 1.00 12.30 ? 75 SER M C 1 ATOM 553 O O . SER A 1 75 ? 54.156 123.259 71.356 1.00 12.86 ? 75 SER M O 1 ATOM 554 C CB . SER A 1 75 ? 53.270 124.030 68.619 1.00 10.81 ? 75 SER M CB 1 ATOM 555 O OG . SER A 1 75 ? 52.505 125.084 68.017 1.00 15.12 ? 75 SER M OG 1 ATOM 556 N N . PHE A 1 76 ? 56.103 123.063 70.373 1.00 11.59 ? 76 PHE M N 1 ATOM 557 C CA . PHE A 1 76 ? 56.648 122.351 71.447 1.00 12.17 ? 76 PHE M CA 1 ATOM 558 C C . PHE A 1 76 ? 56.671 123.199 72.732 1.00 13.43 ? 76 PHE M C 1 ATOM 559 O O . PHE A 1 76 ? 56.246 122.707 73.779 1.00 14.60 ? 76 PHE M O 1 ATOM 560 C CB . PHE A 1 76 ? 58.075 121.877 71.134 1.00 12.11 ? 76 PHE M CB 1 ATOM 561 C CG . PHE A 1 76 ? 58.678 121.086 72.320 1.00 14.72 ? 76 PHE M CG 1 ATOM 562 C CD1 . PHE A 1 76 ? 58.222 119.831 72.617 1.00 16.36 ? 76 PHE M CD1 1 ATOM 563 C CD2 . PHE A 1 76 ? 59.553 121.764 73.135 1.00 19.45 ? 76 PHE M CD2 1 ATOM 564 C CE1 . PHE A 1 76 ? 58.711 119.130 73.760 1.00 18.38 ? 76 PHE M CE1 1 ATOM 565 C CE2 . PHE A 1 76 ? 60.083 121.099 74.235 1.00 21.34 ? 76 PHE M CE2 1 ATOM 566 C CZ . PHE A 1 76 ? 59.646 119.788 74.512 1.00 18.12 ? 76 PHE M CZ 1 ATOM 567 N N . SER A 1 77 ? 57.169 124.426 72.624 1.00 12.14 ? 77 SER M N 1 ATOM 568 C CA . SER A 1 77 ? 57.144 125.338 73.744 1.00 14.25 ? 77 SER M CA 1 ATOM 569 C C . SER A 1 77 ? 55.839 126.007 74.014 1.00 15.13 ? 77 SER M C 1 ATOM 570 O O . SER A 1 77 ? 55.479 126.184 75.200 1.00 15.42 ? 77 SER M O 1 ATOM 571 C CB . SER A 1 77 ? 58.204 126.423 73.587 1.00 17.53 ? 77 SER M CB 1 ATOM 572 O OG . SER A 1 77 ? 59.479 125.842 73.321 1.00 19.02 ? 77 SER M OG 1 ATOM 573 N N . TYR A 1 78 ? 55.125 126.344 72.995 1.00 12.92 ? 78 TYR M N 1 ATOM 574 C CA . TYR A 1 78 ? 54.000 127.227 73.033 1.00 13.48 ? 78 TYR M CA 1 ATOM 575 C C . TYR A 1 78 ? 52.658 126.502 72.801 1.00 11.60 ? 78 TYR M C 1 ATOM 576 O O . TYR A 1 78 ? 51.679 127.161 72.451 1.00 12.46 ? 78 TYR M O 1 ATOM 577 C CB . TYR A 1 78 ? 54.148 128.395 72.079 1.00 11.76 ? 78 TYR M CB 1 ATOM 578 C CG . TYR A 1 78 ? 55.393 129.171 72.436 1.00 15.93 ? 78 TYR M CG 1 ATOM 579 C CD1 . TYR A 1 78 ? 55.577 129.633 73.732 1.00 19.60 ? 78 TYR M CD1 1 ATOM 580 C CD2 . TYR A 1 78 ? 56.375 129.372 71.500 1.00 16.52 ? 78 TYR M CD2 1 ATOM 581 C CE1 . TYR A 1 78 ? 56.720 130.359 74.048 1.00 23.25 ? 78 TYR M CE1 1 ATOM 582 C CE2 . TYR A 1 78 ? 57.568 130.068 71.828 1.00 17.82 ? 78 TYR M CE2 1 ATOM 583 C CZ . TYR A 1 78 ? 57.706 130.534 73.083 1.00 21.54 ? 78 TYR M CZ 1 ATOM 584 O OH . TYR A 1 78 ? 58.890 131.229 73.318 1.00 25.74 ? 78 TYR M OH 1 ATOM 585 N N . TRP A 1 79 ? 52.586 125.212 73.103 1.00 12.42 ? 79 TRP M N 1 ATOM 586 C CA . TRP A 1 79 ? 51.286 124.482 72.975 1.00 12.88 ? 79 TRP M CA 1 ATOM 587 C C . TRP A 1 79 ? 50.150 125.110 73.722 1.00 11.60 ? 79 TRP M C 1 ATOM 588 O O . TRP A 1 79 ? 49.012 125.131 73.272 1.00 11.39 ? 79 TRP M O 1 ATOM 589 C CB . TRP A 1 79 ? 51.471 123.020 73.391 1.00 14.95 ? 79 TRP M CB 1 ATOM 590 C CG . TRP A 1 79 ? 51.945 122.815 74.777 1.00 13.91 ? 79 TRP M CG 1 ATOM 591 C CD1 . TRP A 1 79 ? 53.246 122.885 75.253 1.00 14.70 ? 79 TRP M CD1 1 ATOM 592 C CD2 . TRP A 1 79 ? 51.105 122.686 75.953 1.00 13.07 ? 79 TRP M CD2 1 ATOM 593 N NE1 . TRP A 1 79 ? 53.258 122.690 76.621 1.00 16.53 ? 79 TRP M NE1 1 ATOM 594 C CE2 . TRP A 1 79 ? 51.958 122.568 77.066 1.00 14.78 ? 79 TRP M CE2 1 ATOM 595 C CE3 . TRP A 1 79 ? 49.733 122.573 76.122 1.00 14.44 ? 79 TRP M CE3 1 ATOM 596 C CZ2 . TRP A 1 79 ? 51.462 122.417 78.367 1.00 15.52 ? 79 TRP M CZ2 1 ATOM 597 C CZ3 . TRP A 1 79 ? 49.216 122.426 77.383 1.00 14.32 ? 79 TRP M CZ3 1 ATOM 598 C CH2 . TRP A 1 79 ? 50.072 122.335 78.489 1.00 18.32 ? 79 TRP M CH2 1 ATOM 599 N N . GLN A 1 80 ? 50.455 125.697 74.924 1.00 12.09 ? 80 GLN M N 1 ATOM 600 C CA . GLN A 1 80 ? 49.374 126.340 75.645 1.00 12.00 ? 80 GLN M CA 1 ATOM 601 C C . GLN A 1 80 ? 48.801 127.529 74.913 1.00 11.89 ? 80 GLN M C 1 ATOM 602 O O . GLN A 1 80 ? 47.586 127.857 74.979 1.00 12.69 ? 80 GLN M O 1 ATOM 603 C CB . GLN A 1 80 ? 49.858 126.734 77.040 1.00 13.29 ? 80 GLN M CB 1 ATOM 604 C CG . GLN A 1 80 ? 48.770 127.407 77.867 1.00 15.76 ? 80 GLN M CG 1 ATOM 605 C CD . GLN A 1 80 ? 47.634 126.535 78.230 1.00 16.29 ? 80 GLN M CD 1 ATOM 606 O OE1 . GLN A 1 80 ? 46.476 126.883 77.883 1.00 25.54 ? 80 GLN M OE1 1 ATOM 607 N NE2 . GLN A 1 80 ? 47.904 125.414 78.887 1.00 15.97 ? 80 GLN M NE2 1 ATOM 608 N N . LYS A 1 81 ? 49.633 128.241 74.138 1.00 12.72 ? 81 LYS M N 1 ATOM 609 C CA . LYS A 1 81 ? 49.141 129.368 73.297 1.00 12.24 ? 81 LYS M CA 1 ATOM 610 C C . LYS A 1 81 ? 48.244 128.880 72.194 1.00 13.15 ? 81 LYS M C 1 ATOM 611 O O . LYS A 1 81 ? 47.331 129.589 71.774 1.00 13.99 ? 81 LYS M O 1 ATOM 612 C CB . LYS A 1 81 ? 50.286 130.211 72.733 1.00 13.94 ? 81 LYS M CB 1 ATOM 613 C CG . LYS A 1 81 ? 51.343 130.748 73.814 1.00 21.48 ? 81 LYS M CG 1 ATOM 614 C CD . LYS A 1 81 ? 50.720 131.573 74.796 1.00 27.94 ? 81 LYS M CD 1 ATOM 615 C CE . LYS A 1 81 ? 51.792 132.272 75.755 1.00 32.53 ? 81 LYS M CE 1 ATOM 616 N NZ . LYS A 1 81 ? 51.020 132.948 76.914 1.00 34.06 ? 81 LYS M NZ 1 ATOM 617 N N . ASP A 1 82 ? 48.521 127.676 71.683 1.00 11.00 ? 82 ASP M N 1 ATOM 618 C CA . ASP A 1 82 ? 47.600 127.072 70.666 1.00 12.18 ? 82 ASP M CA 1 ATOM 619 C C . ASP A 1 82 ? 46.223 126.819 71.350 1.00 12.51 ? 82 ASP M C 1 ATOM 620 O O . ASP A 1 82 ? 45.193 127.151 70.755 1.00 11.79 ? 82 ASP M O 1 ATOM 621 C CB . ASP A 1 82 ? 48.172 125.780 70.121 1.00 11.46 ? 82 ASP M CB 1 ATOM 622 C CG . ASP A 1 82 ? 49.496 125.949 69.351 1.00 14.87 ? 82 ASP M CG 1 ATOM 623 O OD1 . ASP A 1 82 ? 49.799 127.032 68.884 1.00 15.62 ? 82 ASP M OD1 1 ATOM 624 O OD2 . ASP A 1 82 ? 50.187 124.888 69.164 1.00 17.00 ? 82 ASP M OD2 1 ATOM 625 N N . ILE A 1 83 ? 46.243 126.219 72.565 1.00 11.73 ? 83 ILE M N 1 ATOM 626 C CA . ILE A 1 83 ? 44.976 125.940 73.269 1.00 11.29 ? 83 ILE M CA 1 ATOM 627 C C . ILE A 1 83 ? 44.291 127.303 73.485 1.00 12.35 ? 83 ILE M C 1 ATOM 628 O O . ILE A 1 83 ? 43.073 127.404 73.336 1.00 12.59 ? 83 ILE M O 1 ATOM 629 C CB . ILE A 1 83 ? 45.218 125.211 74.549 1.00 11.91 ? 83 ILE M CB 1 ATOM 630 C CG1 . ILE A 1 83 ? 45.813 123.837 74.353 1.00 14.09 ? 83 ILE M CG1 1 ATOM 631 C CG2 . ILE A 1 83 ? 43.868 125.163 75.409 1.00 13.11 ? 83 ILE M CG2 1 ATOM 632 C CD1 . ILE A 1 83 ? 46.135 123.022 75.614 1.00 14.15 ? 83 ILE M CD1 1 ATOM 633 N N . ASP A 1 84 ? 45.066 128.341 73.807 1.00 13.33 ? 84 ASP M N 1 ATOM 634 C CA . ASP A 1 84 ? 44.418 129.680 74.064 1.00 14.79 ? 84 ASP M CA 1 ATOM 635 C C . ASP A 1 84 ? 43.691 130.221 72.806 1.00 14.02 ? 84 ASP M C 1 ATOM 636 O O . ASP A 1 84 ? 42.621 130.847 72.907 1.00 14.69 ? 84 ASP M O 1 ATOM 637 C CB . ASP A 1 84 ? 45.423 130.642 74.594 1.00 14.71 ? 84 ASP M CB 1 ATOM 638 C CG . ASP A 1 84 ? 45.893 130.345 76.008 1.00 19.68 ? 84 ASP M CG 1 ATOM 639 O OD1 . ASP A 1 84 ? 45.399 129.434 76.730 1.00 18.35 ? 84 ASP M OD1 1 ATOM 640 O OD2 . ASP A 1 84 ? 46.980 130.944 76.324 1.00 24.06 ? 84 ASP M OD2 1 ATOM 641 N N . VAL A 1 85 ? 44.246 130.009 71.612 1.00 13.03 ? 85 VAL M N 1 ATOM 642 C CA . VAL A 1 85 ? 43.580 130.369 70.382 1.00 11.76 ? 85 VAL M CA 1 ATOM 643 C C . VAL A 1 85 ? 42.297 129.614 70.223 1.00 13.23 ? 85 VAL M C 1 ATOM 644 O O . VAL A 1 85 ? 41.259 130.148 69.915 1.00 12.89 ? 85 VAL M O 1 ATOM 645 C CB . VAL A 1 85 ? 44.465 130.066 69.125 1.00 14.71 ? 85 VAL M CB 1 ATOM 646 C CG1 . VAL A 1 85 ? 43.633 130.204 67.778 1.00 17.35 ? 85 VAL M CG1 1 ATOM 647 C CG2 . VAL A 1 85 ? 45.643 131.028 69.086 1.00 16.50 ? 85 VAL M CG2 1 ATOM 648 N N . LEU A 1 86 ? 42.333 128.325 70.461 1.00 12.63 ? 86 LEU M N 1 ATOM 649 C CA . LEU A 1 86 ? 41.144 127.498 70.342 1.00 11.34 ? 86 LEU M CA 1 ATOM 650 C C . LEU A 1 86 ? 40.050 127.899 71.335 1.00 10.57 ? 86 LEU M C 1 ATOM 651 O O . LEU A 1 86 ? 38.868 127.944 71.003 1.00 11.59 ? 86 LEU M O 1 ATOM 652 C CB . LEU A 1 86 ? 41.468 126.023 70.592 1.00 10.15 ? 86 LEU M CB 1 ATOM 653 C CG . LEU A 1 86 ? 42.284 125.427 69.494 1.00 10.93 ? 86 LEU M CG 1 ATOM 654 C CD1 . LEU A 1 86 ? 43.140 124.233 69.983 1.00 11.56 ? 86 LEU M CD1 1 ATOM 655 C CD2 . LEU A 1 86 ? 41.412 124.971 68.294 1.00 12.04 ? 86 LEU M CD2 1 ATOM 656 N N . ASP A 1 87 ? 40.487 128.235 72.561 1.00 11.90 ? 87 ASP M N 1 ATOM 657 C CA . ASP A 1 87 ? 39.583 128.729 73.647 1.00 15.23 ? 87 ASP M CA 1 ATOM 658 C C . ASP A 1 87 ? 38.993 130.033 73.197 1.00 16.20 ? 87 ASP M C 1 ATOM 659 O O . ASP A 1 87 ? 37.754 130.196 73.306 1.00 16.46 ? 87 ASP M O 1 ATOM 660 C CB . ASP A 1 87 ? 40.447 128.889 74.916 1.00 15.65 ? 87 ASP M CB 1 ATOM 661 C CG . ASP A 1 87 ? 39.651 129.233 76.184 1.00 28.20 ? 87 ASP M CG 1 ATOM 662 O OD1 . ASP A 1 87 ? 38.493 128.835 76.274 1.00 25.53 ? 87 ASP M OD1 1 ATOM 663 O OD2 . ASP A 1 87 ? 40.357 129.588 77.166 1.00 29.29 ? 87 ASP M OD2 1 ATOM 664 N N . GLU A 1 88 ? 39.786 130.990 72.635 1.00 15.83 ? 88 GLU M N 1 ATOM 665 C CA . GLU A 1 88 ? 39.257 132.227 72.091 1.00 17.69 ? 88 GLU M CA 1 ATOM 666 C C . GLU A 1 88 ? 38.219 132.029 71.062 1.00 17.83 ? 88 GLU M C 1 ATOM 667 O O . GLU A 1 88 ? 37.140 132.696 71.065 1.00 17.84 ? 88 GLU M O 1 ATOM 668 C CB A GLU A 1 88 ? 40.426 133.084 71.583 0.70 19.62 ? 88 GLU M CB 1 ATOM 669 C CB B GLU A 1 88 ? 40.349 133.117 71.506 0.30 18.56 ? 88 GLU M CB 1 ATOM 670 C CG A GLU A 1 88 ? 40.150 134.497 71.322 0.70 23.41 ? 88 GLU M CG 1 ATOM 671 C CG B GLU A 1 88 ? 41.256 133.646 72.542 0.30 19.72 ? 88 GLU M CG 1 ATOM 672 C CD A GLU A 1 88 ? 41.446 135.326 71.054 0.70 26.66 ? 88 GLU M CD 1 ATOM 673 C CD B GLU A 1 88 ? 42.380 134.490 71.969 0.30 26.78 ? 88 GLU M CD 1 ATOM 674 O OE1 A GLU A 1 88 ? 42.526 134.710 70.851 0.70 34.85 ? 88 GLU M OE1 1 ATOM 675 O OE1 B GLU A 1 88 ? 42.833 134.259 70.803 0.30 26.35 ? 88 GLU M OE1 1 ATOM 676 O OE2 A GLU A 1 88 ? 41.352 136.582 70.953 0.70 31.96 ? 88 GLU M OE2 1 ATOM 677 O OE2 B GLU A 1 88 ? 42.832 135.386 72.711 0.30 29.16 ? 88 GLU M OE2 1 ATOM 678 N N . LEU A 1 89 ? 38.447 131.038 70.202 1.00 14.78 ? 89 LEU M N 1 ATOM 679 C CA . LEU A 1 89 ? 37.460 130.703 69.160 1.00 12.66 ? 89 LEU M CA 1 ATOM 680 C C . LEU A 1 89 ? 36.220 129.988 69.676 1.00 11.67 ? 89 LEU M C 1 ATOM 681 O O . LEU A 1 89 ? 35.189 129.934 68.920 1.00 15.10 ? 89 LEU M O 1 ATOM 682 C CB . LEU A 1 89 ? 38.135 129.753 68.154 1.00 12.58 ? 89 LEU M CB 1 ATOM 683 C CG . LEU A 1 89 ? 39.188 130.354 67.270 1.00 12.79 ? 89 LEU M CG 1 ATOM 684 C CD1 . LEU A 1 89 ? 39.901 129.238 66.428 1.00 14.74 ? 89 LEU M CD1 1 ATOM 685 C CD2 . LEU A 1 89 ? 38.590 131.382 66.248 1.00 15.64 ? 89 LEU M CD2 1 ATOM 686 N N . ASN A 1 90 ? 36.230 129.456 70.869 1.00 12.53 ? 90 ASN M N 1 ATOM 687 C CA . ASN A 1 90 ? 35.148 128.606 71.376 1.00 12.09 ? 90 ASN M CA 1 ATOM 688 C C . ASN A 1 90 ? 35.026 127.416 70.419 1.00 14.02 ? 90 ASN M C 1 ATOM 689 O O . ASN A 1 90 ? 34.005 126.809 70.210 1.00 13.39 ? 90 ASN M O 1 ATOM 690 C CB . ASN A 1 90 ? 33.827 129.381 71.527 1.00 15.36 ? 90 ASN M CB 1 ATOM 691 C CG . ASN A 1 90 ? 32.888 128.807 72.574 1.00 19.42 ? 90 ASN M CG 1 ATOM 692 O OD1 . ASN A 1 90 ? 33.205 127.912 73.384 1.00 19.19 ? 90 ASN M OD1 1 ATOM 693 N ND2 . ASN A 1 90 ? 31.658 129.412 72.593 1.00 18.30 ? 90 ASN M ND2 1 ATOM 694 N N . ALA A 1 91 ? 36.194 126.995 69.935 1.00 13.68 ? 91 ALA M N 1 ATOM 695 C CA . ALA A 1 91 ? 36.248 125.752 69.145 1.00 11.99 ? 91 ALA M CA 1 ATOM 696 C C . ALA A 1 91 ? 35.867 124.570 69.925 1.00 12.08 ? 91 ALA M C 1 ATOM 697 O O . ALA A 1 91 ? 36.215 124.429 71.108 1.00 13.17 ? 91 ALA M O 1 ATOM 698 C CB . ALA A 1 91 ? 37.719 125.584 68.568 1.00 12.51 ? 91 ALA M CB 1 ATOM 699 N N . THR A 1 92 ? 35.202 123.613 69.225 1.00 11.15 ? 92 THR M N 1 ATOM 700 C CA . THR A 1 92 ? 34.936 122.362 69.822 1.00 11.16 ? 92 THR M CA 1 ATOM 701 C C . THR A 1 92 ? 35.738 121.196 69.294 1.00 10.77 ? 92 THR M C 1 ATOM 702 O O . THR A 1 92 ? 35.578 120.086 69.778 1.00 11.02 ? 92 THR M O 1 ATOM 703 C CB . THR A 1 92 ? 33.447 122.022 69.704 1.00 12.57 ? 92 THR M CB 1 ATOM 704 O OG1 . THR A 1 92 ? 32.936 122.281 68.409 1.00 11.44 ? 92 THR M OG1 1 ATOM 705 C CG2 . THR A 1 92 ? 32.586 122.925 70.745 1.00 14.21 ? 92 THR M CG2 1 ATOM 706 N N . GLY A 1 93 ? 36.575 121.462 68.280 1.00 10.30 ? 93 GLY M N 1 ATOM 707 C CA . GLY A 1 93 ? 37.488 120.454 67.853 1.00 8.76 ? 93 GLY M CA 1 ATOM 708 C C . GLY A 1 93 ? 38.855 120.999 67.442 1.00 8.34 ? 93 GLY M C 1 ATOM 709 O O . GLY A 1 93 ? 38.941 122.143 67.051 1.00 8.85 ? 93 GLY M O 1 ATOM 710 N N . TYR A 1 94 ? 39.866 120.134 67.516 1.00 8.63 ? 94 TYR M N 1 ATOM 711 C CA . TYR A 1 94 ? 41.218 120.495 67.077 1.00 7.12 ? 94 TYR M CA 1 ATOM 712 C C . TYR A 1 94 ? 41.833 119.250 66.510 1.00 9.07 ? 94 TYR M C 1 ATOM 713 O O . TYR A 1 94 ? 41.928 118.260 67.196 1.00 9.26 ? 94 TYR M O 1 ATOM 714 C CB . TYR A 1 94 ? 42.062 121.059 68.214 1.00 7.72 ? 94 TYR M CB 1 ATOM 715 C CG . TYR A 1 94 ? 43.522 121.364 67.918 1.00 8.39 ? 94 TYR M CG 1 ATOM 716 C CD1 . TYR A 1 94 ? 43.787 122.131 66.792 1.00 9.38 ? 94 TYR M CD1 1 ATOM 717 C CD2 . TYR A 1 94 ? 44.564 120.973 68.712 1.00 8.51 ? 94 TYR M CD2 1 ATOM 718 C CE1 . TYR A 1 94 ? 45.117 122.450 66.470 1.00 7.64 ? 94 TYR M CE1 1 ATOM 719 C CE2 . TYR A 1 94 ? 45.864 121.345 68.427 1.00 9.04 ? 94 TYR M CE2 1 ATOM 720 C CZ . TYR A 1 94 ? 46.118 122.092 67.334 1.00 8.08 ? 94 TYR M CZ 1 ATOM 721 O OH . TYR A 1 94 ? 47.466 122.403 67.049 1.00 11.65 ? 94 TYR M OH 1 ATOM 722 N N . ARG A 1 95 ? 42.288 119.364 65.277 1.00 8.52 ? 95 ARG M N 1 ATOM 723 C CA . ARG A 1 95 ? 43.065 118.269 64.652 1.00 8.24 ? 95 ARG M CA 1 ATOM 724 C C . ARG A 1 95 ? 44.535 118.576 64.731 1.00 8.06 ? 95 ARG M C 1 ATOM 725 O O . ARG A 1 95 ? 44.935 119.655 64.347 1.00 9.34 ? 95 ARG M O 1 ATOM 726 C CB . ARG A 1 95 ? 42.662 118.056 63.242 1.00 9.04 ? 95 ARG M CB 1 ATOM 727 C CG . ARG A 1 95 ? 43.515 117.057 62.521 1.00 8.02 ? 95 ARG M CG 1 ATOM 728 C CD . ARG A 1 95 ? 42.886 116.719 61.154 1.00 10.97 ? 95 ARG M CD 1 ATOM 729 N NE . ARG A 1 95 ? 43.773 115.819 60.431 1.00 13.06 ? 95 ARG M NE 1 ATOM 730 C CZ . ARG A 1 95 ? 44.382 116.080 59.305 1.00 10.72 ? 95 ARG M CZ 1 ATOM 731 N NH1 . ARG A 1 95 ? 44.094 117.108 58.574 1.00 12.59 ? 95 ARG M NH1 1 ATOM 732 N NH2 . ARG A 1 95 ? 45.286 115.230 58.870 1.00 10.85 ? 95 ARG M NH2 1 ATOM 733 N N . PHE A 1 96 ? 45.280 117.689 65.315 1.00 7.30 ? 96 PHE M N 1 ATOM 734 C CA . PHE A 1 96 ? 46.706 117.766 65.404 1.00 6.95 ? 96 PHE M CA 1 ATOM 735 C C . PHE A 1 96 ? 47.289 116.445 65.063 1.00 9.14 ? 96 PHE M C 1 ATOM 736 O O . PHE A 1 96 ? 46.561 115.448 65.002 1.00 8.71 ? 96 PHE M O 1 ATOM 737 C CB . PHE A 1 96 ? 47.205 118.332 66.737 1.00 8.30 ? 96 PHE M CB 1 ATOM 738 C CG . PHE A 1 96 ? 47.050 117.455 67.909 1.00 7.67 ? 96 PHE M CG 1 ATOM 739 C CD1 . PHE A 1 96 ? 45.849 117.473 68.666 1.00 8.75 ? 96 PHE M CD1 1 ATOM 740 C CD2 . PHE A 1 96 ? 48.019 116.565 68.264 1.00 8.59 ? 96 PHE M CD2 1 ATOM 741 C CE1 . PHE A 1 96 ? 45.760 116.644 69.767 1.00 8.83 ? 96 PHE M CE1 1 ATOM 742 C CE2 . PHE A 1 96 ? 47.873 115.681 69.282 1.00 11.86 ? 96 PHE M CE2 1 ATOM 743 C CZ . PHE A 1 96 ? 46.738 115.710 70.071 1.00 10.05 ? 96 PHE M CZ 1 ATOM 744 N N . SER A 1 97 ? 48.616 116.391 64.851 1.00 7.91 ? 97 SER M N 1 ATOM 745 C CA . SER A 1 97 ? 49.277 115.113 64.607 1.00 7.34 ? 97 SER M CA 1 ATOM 746 C C . SER A 1 97 ? 50.300 114.799 65.637 1.00 7.33 ? 97 SER M C 1 ATOM 747 O O . SER A 1 97 ? 50.851 115.703 66.315 1.00 7.95 ? 97 SER M O 1 ATOM 748 C CB . SER A 1 97 ? 49.801 115.004 63.216 1.00 8.28 ? 97 SER M CB 1 ATOM 749 O OG . SER A 1 97 ? 51.114 115.563 63.047 1.00 8.18 ? 97 SER M OG 1 ATOM 750 N N . ILE A 1 98 ? 50.508 113.521 65.877 1.00 6.64 ? 98 ILE M N 1 ATOM 751 C CA . ILE A 1 98 ? 51.583 113.015 66.698 1.00 5.04 ? 98 ILE M CA 1 ATOM 752 C C . ILE A 1 98 ? 52.790 112.792 65.840 1.00 8.40 ? 98 ILE M C 1 ATOM 753 O O . ILE A 1 98 ? 52.700 112.157 64.784 1.00 9.14 ? 98 ILE M O 1 ATOM 754 C CB . ILE A 1 98 ? 51.178 111.735 67.436 1.00 7.07 ? 98 ILE M CB 1 ATOM 755 C CG1 . ILE A 1 98 ? 50.101 111.997 68.451 1.00 10.28 ? 98 ILE M CG1 1 ATOM 756 C CG2 . ILE A 1 98 ? 52.431 111.057 68.148 1.00 8.36 ? 98 ILE M CG2 1 ATOM 757 C CD1 . ILE A 1 98 ? 49.455 110.722 69.113 1.00 10.78 ? 98 ILE M CD1 1 ATOM 758 N N . ALA A 1 99 ? 53.939 113.280 66.237 1.00 7.23 ? 99 ALA M N 1 ATOM 759 C CA . ALA A 1 99 ? 55.173 113.027 65.500 1.00 7.49 ? 99 ALA M CA 1 ATOM 760 C C . ALA A 1 99 ? 55.735 111.683 65.951 1.00 6.38 ? 99 ALA M C 1 ATOM 761 O O . ALA A 1 99 ? 56.147 111.518 67.108 1.00 7.79 ? 99 ALA M O 1 ATOM 762 C CB . ALA A 1 99 ? 56.246 114.178 65.760 1.00 8.25 ? 99 ALA M CB 1 ATOM 763 N N . TRP A 1 100 ? 55.749 110.719 65.067 1.00 7.28 ? 100 TRP M N 1 ATOM 764 C CA . TRP A 1 100 ? 56.323 109.418 65.363 1.00 7.49 ? 100 TRP M CA 1 ATOM 765 C C . TRP A 1 100 ? 57.716 109.637 65.948 1.00 7.71 ? 100 TRP M C 1 ATOM 766 O O . TRP A 1 100 ? 58.107 108.883 66.870 1.00 7.87 ? 100 TRP M O 1 ATOM 767 C CB . TRP A 1 100 ? 56.289 108.593 64.086 1.00 7.50 ? 100 TRP M CB 1 ATOM 768 C CG . TRP A 1 100 ? 56.681 107.180 64.072 1.00 6.49 ? 100 TRP M CG 1 ATOM 769 C CD1 . TRP A 1 100 ? 57.451 106.508 64.954 1.00 8.63 ? 100 TRP M CD1 1 ATOM 770 C CD2 . TRP A 1 100 ? 56.328 106.277 63.024 1.00 6.27 ? 100 TRP M CD2 1 ATOM 771 N NE1 . TRP A 1 100 ? 57.537 105.174 64.553 1.00 10.16 ? 100 TRP M NE1 1 ATOM 772 C CE2 . TRP A 1 100 ? 56.894 105.031 63.344 1.00 7.26 ? 100 TRP M CE2 1 ATOM 773 C CE3 . TRP A 1 100 ? 55.600 106.416 61.882 1.00 8.32 ? 100 TRP M CE3 1 ATOM 774 C CZ2 . TRP A 1 100 ? 56.752 103.912 62.514 1.00 9.40 ? 100 TRP M CZ2 1 ATOM 775 C CZ3 . TRP A 1 100 ? 55.485 105.281 61.042 1.00 8.67 ? 100 TRP M CZ3 1 ATOM 776 C CH2 . TRP A 1 100 ? 56.011 104.087 61.413 1.00 9.88 ? 100 TRP M CH2 1 ATOM 777 N N . SER A 1 101 ? 58.529 110.475 65.352 1.00 7.01 ? 101 SER M N 1 ATOM 778 C CA . SER A 1 101 ? 59.886 110.717 65.816 1.00 8.06 ? 101 SER M CA 1 ATOM 779 C C . SER A 1 101 ? 59.949 111.352 67.176 1.00 7.63 ? 101 SER M C 1 ATOM 780 O O . SER A 1 101 ? 61.036 111.295 67.782 1.00 8.19 ? 101 SER M O 1 ATOM 781 C CB A SER A 1 101 ? 60.621 111.665 64.833 0.70 8.01 ? 101 SER M CB 1 ATOM 782 C CB B SER A 1 101 ? 60.682 111.489 64.769 0.30 8.52 ? 101 SER M CB 1 ATOM 783 O OG A SER A 1 101 ? 60.860 110.995 63.634 0.70 9.20 ? 101 SER M OG 1 ATOM 784 O OG B SER A 1 101 ? 60.079 112.729 64.560 0.30 11.61 ? 101 SER M OG 1 ATOM 785 N N . ARG A 1 102 ? 58.854 111.861 67.730 1.00 8.06 ? 102 ARG M N 1 ATOM 786 C CA . ARG A 1 102 ? 58.865 112.438 69.078 1.00 7.97 ? 102 ARG M CA 1 ATOM 787 C C . ARG A 1 102 ? 58.595 111.324 70.101 1.00 7.78 ? 102 ARG M C 1 ATOM 788 O O . ARG A 1 102 ? 59.181 111.382 71.168 1.00 9.99 ? 102 ARG M O 1 ATOM 789 C CB . ARG A 1 102 ? 57.861 113.552 69.266 1.00 7.00 ? 102 ARG M CB 1 ATOM 790 C CG . ARG A 1 102 ? 57.902 114.227 70.601 1.00 7.68 ? 102 ARG M CG 1 ATOM 791 C CD . ARG A 1 102 ? 57.053 115.469 70.686 1.00 8.13 ? 102 ARG M CD 1 ATOM 792 N NE . ARG A 1 102 ? 57.432 116.464 69.702 1.00 7.76 ? 102 ARG M NE 1 ATOM 793 C CZ . ARG A 1 102 ? 58.502 117.249 69.763 1.00 8.79 ? 102 ARG M CZ 1 ATOM 794 N NH1 . ARG A 1 102 ? 59.333 117.182 70.773 1.00 9.13 ? 102 ARG M NH1 1 ATOM 795 N NH2 . ARG A 1 102 ? 58.745 118.100 68.785 1.00 9.78 ? 102 ARG M NH2 1 ATOM 796 N N . ILE A 1 103 ? 57.800 110.327 69.775 1.00 9.28 ? 103 ILE M N 1 ATOM 797 C CA . ILE A 1 103 ? 57.526 109.240 70.734 1.00 8.51 ? 103 ILE M CA 1 ATOM 798 C C . ILE A 1 103 ? 58.319 108.027 70.585 1.00 8.76 ? 103 ILE M C 1 ATOM 799 O O . ILE A 1 103 ? 58.590 107.356 71.577 1.00 9.21 ? 103 ILE M O 1 ATOM 800 C CB . ILE A 1 103 ? 56.089 109.078 70.992 1.00 12.24 ? 103 ILE M CB 1 ATOM 801 C CG1 . ILE A 1 103 ? 55.431 108.477 69.842 1.00 12.53 ? 103 ILE M CG1 1 ATOM 802 C CG2 . ILE A 1 103 ? 55.255 110.395 71.412 1.00 11.90 ? 103 ILE M CG2 1 ATOM 803 C CD1 . ILE A 1 103 ? 53.891 107.994 70.185 1.00 14.94 ? 103 ILE M CD1 1 ATOM 804 N N . ILE A 1 104 ? 58.755 107.712 69.337 1.00 8.17 ? 104 ILE M N 1 ATOM 805 C CA . ILE A 1 104 ? 59.695 106.631 69.094 1.00 8.54 ? 104 ILE M CA 1 ATOM 806 C C . ILE A 1 104 ? 60.782 107.138 68.165 1.00 8.62 ? 104 ILE M C 1 ATOM 807 O O . ILE A 1 104 ? 60.742 106.873 66.957 1.00 9.04 ? 104 ILE M O 1 ATOM 808 C CB . ILE A 1 104 ? 59.055 105.345 68.490 1.00 8.25 ? 104 ILE M CB 1 ATOM 809 C CG1 . ILE A 1 104 ? 57.731 104.942 69.210 1.00 9.80 ? 104 ILE M CG1 1 ATOM 810 C CG2 . ILE A 1 104 ? 60.012 104.130 68.470 1.00 8.98 ? 104 ILE M CG2 1 ATOM 811 C CD1 . ILE A 1 104 ? 56.942 103.820 68.503 1.00 9.62 ? 104 ILE M CD1 1 ATOM 812 N N . PRO A 1 105 ? 61.749 107.839 68.720 1.00 8.31 ? 105 PRO M N 1 ATOM 813 C CA . PRO A 1 105 ? 62.765 108.434 67.860 1.00 8.07 ? 105 PRO M CA 1 ATOM 814 C C . PRO A 1 105 ? 63.522 107.406 67.037 1.00 9.41 ? 105 PRO M C 1 ATOM 815 O O . PRO A 1 105 ? 64.002 107.774 65.922 1.00 12.19 ? 105 PRO M O 1 ATOM 816 C CB . PRO A 1 105 ? 63.677 109.107 68.880 1.00 8.33 ? 105 PRO M CB 1 ATOM 817 C CG . PRO A 1 105 ? 62.796 109.464 70.001 1.00 10.77 ? 105 PRO M CG 1 ATOM 818 C CD . PRO A 1 105 ? 61.806 108.385 70.102 1.00 8.96 ? 105 PRO M CD 1 ATOM 819 N N . ARG A 1 106 ? 63.677 106.193 67.506 1.00 8.65 ? 106 ARG M N 1 ATOM 820 C CA . ARG A 1 106 ? 64.394 105.186 66.759 1.00 8.69 ? 106 ARG M CA 1 ATOM 821 C C . ARG A 1 106 ? 63.490 104.325 65.849 1.00 8.03 ? 106 ARG M C 1 ATOM 822 O O . ARG A 1 106 ? 63.949 103.332 65.273 1.00 9.39 ? 106 ARG M O 1 ATOM 823 C CB . ARG A 1 106 ? 65.233 104.283 67.670 1.00 9.44 ? 106 ARG M CB 1 ATOM 824 C CG . ARG A 1 106 ? 66.138 105.022 68.536 1.00 8.60 ? 106 ARG M CG 1 ATOM 825 C CD . ARG A 1 106 ? 66.923 104.113 69.503 1.00 10.97 ? 106 ARG M CD 1 ATOM 826 N NE . ARG A 1 106 ? 67.611 103.023 68.841 1.00 8.80 ? 106 ARG M NE 1 ATOM 827 C CZ . ARG A 1 106 ? 68.179 102.001 69.484 1.00 11.07 ? 106 ARG M CZ 1 ATOM 828 N NH1 . ARG A 1 106 ? 68.055 101.871 70.747 1.00 13.25 ? 106 ARG M NH1 1 ATOM 829 N NH2 . ARG A 1 106 ? 68.695 101.033 68.728 1.00 11.94 ? 106 ARG M NH2 1 ATOM 830 N N . GLY A 1 107 ? 62.265 104.801 65.603 1.00 9.10 ? 107 GLY M N 1 ATOM 831 C CA . GLY A 1 107 ? 61.343 104.250 64.641 1.00 8.36 ? 107 GLY M CA 1 ATOM 832 C C . GLY A 1 107 ? 60.615 102.995 65.121 1.00 10.20 ? 107 GLY M C 1 ATOM 833 O O . GLY A 1 107 ? 59.414 102.985 65.106 1.00 11.17 ? 107 GLY M O 1 ATOM 834 N N . LYS A 1 108 ? 61.382 101.939 65.347 1.00 9.17 ? 108 LYS M N 1 ATOM 835 C CA . LYS A 1 108 ? 60.874 100.659 65.796 1.00 10.28 ? 108 LYS M CA 1 ATOM 836 C C . LYS A 1 108 ? 60.659 100.675 67.290 1.00 11.42 ? 108 LYS M C 1 ATOM 837 O O . LYS A 1 108 ? 61.590 100.923 68.043 1.00 11.64 ? 108 LYS M O 1 ATOM 838 C CB . LYS A 1 108 ? 61.877 99.559 65.421 1.00 11.14 ? 108 LYS M CB 1 ATOM 839 C CG . LYS A 1 108 ? 61.463 98.222 65.728 1.00 16.48 ? 108 LYS M CG 1 ATOM 840 C CD . LYS A 1 108 ? 62.458 97.200 65.211 1.00 24.61 ? 108 LYS M CD 1 ATOM 841 C CE . LYS A 1 108 ? 62.201 95.766 65.908 1.00 32.36 ? 108 LYS M CE 1 ATOM 842 N NZ . LYS A 1 108 ? 60.768 95.489 66.278 1.00 44.04 ? 108 LYS M NZ 1 ATOM 843 N N . ARG A 1 109 ? 59.440 100.341 67.730 1.00 11.25 ? 109 ARG M N 1 ATOM 844 C CA . ARG A 1 109 ? 59.060 100.447 69.118 1.00 11.21 ? 109 ARG M CA 1 ATOM 845 C C . ARG A 1 109 ? 59.945 99.665 70.093 1.00 10.39 ? 109 ARG M C 1 ATOM 846 O O . ARG A 1 109 ? 60.164 100.201 71.237 1.00 12.27 ? 109 ARG M O 1 ATOM 847 C CB . ARG A 1 109 ? 57.580 100.033 69.279 1.00 12.96 ? 109 ARG M CB 1 ATOM 848 C CG . ARG A 1 109 ? 57.049 100.241 70.733 1.00 13.20 ? 109 ARG M CG 1 ATOM 849 C CD . ARG A 1 109 ? 55.642 99.902 70.683 1.00 19.40 ? 109 ARG M CD 1 ATOM 850 N NE . ARG A 1 109 ? 55.123 99.947 72.027 1.00 18.97 ? 109 ARG M NE 1 ATOM 851 C CZ . ARG A 1 109 ? 53.876 99.638 72.269 1.00 22.51 ? 109 ARG M CZ 1 ATOM 852 N NH1 . ARG A 1 109 ? 53.075 99.360 71.200 1.00 21.00 ? 109 ARG M NH1 1 ATOM 853 N NH2 . ARG A 1 109 ? 53.490 99.620 73.498 1.00 20.14 ? 109 ARG M NH2 1 ATOM 854 N N . SER A 1 110 ? 60.378 98.533 69.644 1.00 13.06 ? 110 SER M N 1 ATOM 855 C CA . SER A 1 110 ? 61.234 97.695 70.533 1.00 12.81 ? 110 SER M CA 1 ATOM 856 C C . SER A 1 110 ? 62.512 98.422 70.931 1.00 13.25 ? 110 SER M C 1 ATOM 857 O O . SER A 1 110 ? 63.167 98.007 71.924 1.00 15.98 ? 110 SER M O 1 ATOM 858 C CB . SER A 1 110 ? 61.611 96.381 69.942 1.00 15.68 ? 110 SER M CB 1 ATOM 859 O OG . SER A 1 110 ? 62.333 96.576 68.761 1.00 17.92 ? 110 SER M OG 1 ATOM 860 N N . ARG A 1 111 ? 62.934 99.451 70.170 1.00 11.42 ? 111 ARG M N 1 ATOM 861 C CA . ARG A 1 111 ? 64.144 100.204 70.508 1.00 9.82 ? 111 ARG M CA 1 ATOM 862 C C . ARG A 1 111 ? 63.951 101.186 71.608 1.00 12.74 ? 111 ARG M C 1 ATOM 863 O O . ARG A 1 111 ? 64.902 101.908 72.052 1.00 14.18 ? 111 ARG M O 1 ATOM 864 C CB . ARG A 1 111 ? 64.632 100.877 69.244 1.00 10.62 ? 111 ARG M CB 1 ATOM 865 C CG . ARG A 1 111 ? 64.990 99.898 68.145 1.00 10.51 ? 111 ARG M CG 1 ATOM 866 C CD . ARG A 1 111 ? 65.381 100.588 66.815 1.00 9.62 ? 111 ARG M CD 1 ATOM 867 N NE . ARG A 1 111 ? 65.692 99.601 65.841 1.00 9.62 ? 111 ARG M NE 1 ATOM 868 C CZ . ARG A 1 111 ? 65.750 99.841 64.514 1.00 11.58 ? 111 ARG M CZ 1 ATOM 869 N NH1 . ARG A 1 111 ? 65.409 100.993 64.053 1.00 10.52 ? 111 ARG M NH1 1 ATOM 870 N NH2 . ARG A 1 111 ? 66.082 98.899 63.681 1.00 13.11 ? 111 ARG M NH2 1 ATOM 871 N N . GLY A 1 112 ? 62.708 101.387 72.071 1.00 11.86 ? 112 GLY M N 1 ATOM 872 C CA . GLY A 1 112 ? 62.463 102.306 73.175 1.00 12.28 ? 112 GLY M CA 1 ATOM 873 C C . GLY A 1 112 ? 61.554 103.428 72.835 1.00 13.89 ? 112 GLY M C 1 ATOM 874 O O . GLY A 1 112 ? 61.418 103.803 71.686 1.00 14.18 ? 112 GLY M O 1 ATOM 875 N N . VAL A 1 113 ? 60.941 104.008 73.831 1.00 11.89 ? 113 VAL M N 1 ATOM 876 C CA . VAL A 1 113 ? 60.037 105.124 73.711 1.00 12.02 ? 113 VAL M CA 1 ATOM 877 C C . VAL A 1 113 ? 60.645 106.328 74.364 1.00 15.58 ? 113 VAL M C 1 ATOM 878 O O . VAL A 1 113 ? 61.498 106.249 75.294 1.00 18.72 ? 113 VAL M O 1 ATOM 879 C CB . VAL A 1 113 ? 58.599 104.782 74.252 1.00 14.59 ? 113 VAL M CB 1 ATOM 880 C CG1 . VAL A 1 113 ? 57.998 103.515 73.534 1.00 16.61 ? 113 VAL M CG1 1 ATOM 881 C CG2 . VAL A 1 113 ? 58.570 104.774 75.708 1.00 18.40 ? 113 VAL M CG2 1 ATOM 882 N N . ASN A 1 114 ? 60.288 107.483 73.908 1.00 10.48 ? 114 ASN M N 1 ATOM 883 C CA . ASN A 1 114 ? 60.636 108.724 74.547 1.00 9.04 ? 114 ASN M CA 1 ATOM 884 C C . ASN A 1 114 ? 59.553 109.204 75.523 1.00 11.72 ? 114 ASN M C 1 ATOM 885 O O . ASN A 1 114 ? 58.552 109.834 75.123 1.00 11.86 ? 114 ASN M O 1 ATOM 886 C CB . ASN A 1 114 ? 60.849 109.794 73.474 1.00 9.53 ? 114 ASN M CB 1 ATOM 887 C CG . ASN A 1 114 ? 61.261 111.126 73.973 1.00 11.82 ? 114 ASN M CG 1 ATOM 888 O OD1 . ASN A 1 114 ? 61.621 111.257 75.182 1.00 15.02 ? 114 ASN M OD1 1 ATOM 889 N ND2 . ASN A 1 114 ? 61.150 112.166 73.148 1.00 11.80 ? 114 ASN M ND2 1 ATOM 890 N N . GLU A 1 115 ? 59.804 108.968 76.814 1.00 12.14 ? 115 GLU M N 1 ATOM 891 C CA . GLU A 1 115 ? 58.776 109.274 77.798 1.00 12.29 ? 115 GLU M CA 1 ATOM 892 C C . GLU A 1 115 ? 58.451 110.755 77.836 1.00 10.84 ? 115 GLU M C 1 ATOM 893 O O . GLU A 1 115 ? 57.299 111.110 78.024 1.00 12.94 ? 115 GLU M O 1 ATOM 894 C CB . GLU A 1 115 ? 59.194 108.765 79.172 1.00 13.92 ? 115 GLU M CB 1 ATOM 895 C CG . GLU A 1 115 ? 57.980 108.696 80.093 1.00 23.99 ? 115 GLU M CG 1 ATOM 896 C CD . GLU A 1 115 ? 56.802 107.876 79.538 1.00 31.97 ? 115 GLU M CD 1 ATOM 897 O OE1 . GLU A 1 115 ? 57.000 106.733 78.968 1.00 36.66 ? 115 GLU M OE1 1 ATOM 898 O OE2 . GLU A 1 115 ? 55.647 108.455 79.666 1.00 38.55 ? 115 GLU M OE2 1 ATOM 899 N N . LYS A 1 116 ? 59.441 111.636 77.625 1.00 10.28 ? 116 LYS M N 1 ATOM 900 C CA . LYS A 1 116 ? 59.154 113.039 77.566 1.00 12.19 ? 116 LYS M CA 1 ATOM 901 C C . LYS A 1 116 ? 58.290 113.471 76.375 1.00 11.20 ? 116 LYS M C 1 ATOM 902 O O . LYS A 1 116 ? 57.510 114.410 76.477 1.00 12.73 ? 116 LYS M O 1 ATOM 903 C CB . LYS A 1 116 ? 60.454 113.884 77.595 1.00 16.79 ? 116 LYS M CB 1 ATOM 904 C CG . LYS A 1 116 ? 61.180 113.673 78.895 1.00 25.59 ? 116 LYS M CG 1 ATOM 905 C CD . LYS A 1 116 ? 60.422 114.063 80.145 1.00 34.44 ? 116 LYS M CD 1 ATOM 906 C CE . LYS A 1 116 ? 59.615 115.388 80.126 1.00 41.10 ? 116 LYS M CE 1 ATOM 907 N NZ . LYS A 1 116 ? 58.248 115.192 80.888 1.00 42.29 ? 116 LYS M NZ 1 ATOM 908 N N . GLY A 1 117 ? 58.423 112.730 75.276 1.00 11.87 ? 117 GLY M N 1 ATOM 909 C CA . GLY A 1 117 ? 57.546 112.910 74.112 1.00 10.50 ? 117 GLY M CA 1 ATOM 910 C C . GLY A 1 117 ? 56.161 112.570 74.369 1.00 9.75 ? 117 GLY M C 1 ATOM 911 O O . GLY A 1 117 ? 55.209 113.262 73.989 1.00 10.82 ? 117 GLY M O 1 ATOM 912 N N . ILE A 1 118 ? 55.979 111.448 75.035 1.00 9.28 ? 118 ILE M N 1 ATOM 913 C CA . ILE A 1 118 ? 54.674 110.979 75.438 1.00 11.04 ? 118 ILE M CA 1 ATOM 914 C C . ILE A 1 118 ? 54.031 111.967 76.349 1.00 10.50 ? 118 ILE M C 1 ATOM 915 O O . ILE A 1 118 ? 52.880 112.331 76.159 1.00 11.24 ? 118 ILE M O 1 ATOM 916 C CB A ILE A 1 118 ? 54.768 109.613 76.047 0.70 12.06 ? 118 ILE M CB 1 ATOM 917 C CB B ILE A 1 118 ? 54.808 109.654 76.241 0.30 10.64 ? 118 ILE M CB 1 ATOM 918 C CG1 A ILE A 1 118 ? 55.109 108.591 74.925 0.70 13.92 ? 118 ILE M CG1 1 ATOM 919 C CG1 B ILE A 1 118 ? 55.192 108.470 75.325 0.30 11.61 ? 118 ILE M CG1 1 ATOM 920 C CG2 A ILE A 1 118 ? 53.413 109.236 76.639 0.70 14.91 ? 118 ILE M CG2 1 ATOM 921 C CG2 B ILE A 1 118 ? 53.529 109.344 77.039 0.30 12.61 ? 118 ILE M CG2 1 ATOM 922 C CD1 A ILE A 1 118 ? 55.571 107.200 75.422 0.70 12.34 ? 118 ILE M CD1 1 ATOM 923 C CD1 B ILE A 1 118 ? 54.088 107.959 74.360 0.30 9.35 ? 118 ILE M CD1 1 ATOM 924 N N . ASP A 1 119 ? 54.802 112.509 77.298 1.00 10.03 ? 119 ASP M N 1 ATOM 925 C CA . ASP A 1 119 ? 54.300 113.534 78.210 1.00 11.03 ? 119 ASP M CA 1 ATOM 926 C C . ASP A 1 119 ? 53.865 114.822 77.554 1.00 9.95 ? 119 ASP M C 1 ATOM 927 O O . ASP A 1 119 ? 52.849 115.419 77.953 1.00 11.57 ? 119 ASP M O 1 ATOM 928 C CB . ASP A 1 119 ? 55.316 113.800 79.291 1.00 13.82 ? 119 ASP M CB 1 ATOM 929 C CG . ASP A 1 119 ? 55.504 112.619 80.221 1.00 20.62 ? 119 ASP M CG 1 ATOM 930 O OD1 . ASP A 1 119 ? 54.743 111.583 80.152 1.00 31.13 ? 119 ASP M OD1 1 ATOM 931 O OD2 . ASP A 1 119 ? 56.489 112.749 81.025 1.00 35.98 ? 119 ASP M OD2 1 ATOM 932 N N . TYR A 1 120 ? 54.541 115.224 76.501 1.00 9.82 ? 120 TYR M N 1 ATOM 933 C CA . TYR A 1 120 ? 54.164 116.384 75.694 1.00 9.40 ? 120 TYR M CA 1 ATOM 934 C C . TYR A 1 120 ? 52.723 116.251 75.193 1.00 9.19 ? 120 TYR M C 1 ATOM 935 O O . TYR A 1 120 ? 51.880 117.119 75.365 1.00 10.56 ? 120 TYR M O 1 ATOM 936 C CB . TYR A 1 120 ? 55.109 116.540 74.557 1.00 10.56 ? 120 TYR M CB 1 ATOM 937 C CG . TYR A 1 120 ? 54.718 117.648 73.609 1.00 10.41 ? 120 TYR M CG 1 ATOM 938 C CD1 . TYR A 1 120 ? 54.761 118.997 73.933 1.00 14.50 ? 120 TYR M CD1 1 ATOM 939 C CD2 . TYR A 1 120 ? 54.142 117.327 72.441 1.00 10.21 ? 120 TYR M CD2 1 ATOM 940 C CE1 . TYR A 1 120 ? 54.357 119.997 73.036 1.00 12.07 ? 120 TYR M CE1 1 ATOM 941 C CE2 . TYR A 1 120 ? 53.767 118.277 71.528 1.00 9.80 ? 120 TYR M CE2 1 ATOM 942 C CZ . TYR A 1 120 ? 53.806 119.630 71.818 1.00 13.61 ? 120 TYR M CZ 1 ATOM 943 O OH . TYR A 1 120 ? 53.393 120.591 70.897 1.00 14.66 ? 120 TYR M OH 1 ATOM 944 N N . TYR A 1 121 ? 52.421 115.095 74.596 1.00 9.09 ? 121 TYR M N 1 ATOM 945 C CA . TYR A 1 121 ? 51.087 114.917 74.052 1.00 7.60 ? 121 TYR M CA 1 ATOM 946 C C . TYR A 1 121 ? 50.057 114.741 75.169 1.00 8.65 ? 121 TYR M C 1 ATOM 947 O O . TYR A 1 121 ? 48.956 115.170 74.992 1.00 10.59 ? 121 TYR M O 1 ATOM 948 C CB . TYR A 1 121 ? 51.068 113.769 73.002 1.00 9.00 ? 121 TYR M CB 1 ATOM 949 C CG . TYR A 1 121 ? 51.894 114.107 71.774 1.00 7.36 ? 121 TYR M CG 1 ATOM 950 C CD1 . TYR A 1 121 ? 51.477 115.112 70.918 1.00 6.51 ? 121 TYR M CD1 1 ATOM 951 C CD2 . TYR A 1 121 ? 53.068 113.448 71.487 1.00 8.38 ? 121 TYR M CD2 1 ATOM 952 C CE1 . TYR A 1 121 ? 52.227 115.441 69.834 1.00 6.29 ? 121 TYR M CE1 1 ATOM 953 C CE2 . TYR A 1 121 ? 53.875 113.818 70.387 1.00 7.36 ? 121 TYR M CE2 1 ATOM 954 C CZ . TYR A 1 121 ? 53.402 114.781 69.594 1.00 6.13 ? 121 TYR M CZ 1 ATOM 955 O OH . TYR A 1 121 ? 54.237 115.116 68.535 1.00 7.60 ? 121 TYR M OH 1 ATOM 956 N N . HIS A 1 122 ? 50.441 114.038 76.233 1.00 10.01 ? 122 HIS M N 1 ATOM 957 C CA . HIS A 1 122 ? 49.499 113.945 77.345 1.00 11.30 ? 122 HIS M CA 1 ATOM 958 C C . HIS A 1 122 ? 49.099 115.321 77.846 1.00 10.54 ? 122 HIS M C 1 ATOM 959 O O . HIS A 1 122 ? 47.881 115.547 78.077 1.00 12.54 ? 122 HIS M O 1 ATOM 960 C CB . HIS A 1 122 ? 50.144 113.199 78.535 1.00 11.91 ? 122 HIS M CB 1 ATOM 961 C CG . HIS A 1 122 ? 50.145 111.747 78.433 1.00 17.19 ? 122 HIS M CG 1 ATOM 962 N ND1 . HIS A 1 122 ? 48.978 111.024 78.161 1.00 22.52 ? 122 HIS M ND1 1 ATOM 963 C CD2 . HIS A 1 122 ? 51.073 110.845 78.816 1.00 20.16 ? 122 HIS M CD2 1 ATOM 964 C CE1 . HIS A 1 122 ? 49.295 109.748 78.149 1.00 19.00 ? 122 HIS M CE1 1 ATOM 965 N NE2 . HIS A 1 122 ? 50.518 109.598 78.615 1.00 22.59 ? 122 HIS M NE2 1 ATOM 966 N N . GLY A 1 123 ? 50.060 116.278 77.985 1.00 11.36 ? 123 GLY M N 1 ATOM 967 C CA . GLY A 1 123 ? 49.729 117.593 78.416 1.00 11.07 ? 123 GLY M CA 1 ATOM 968 C C . GLY A 1 123 ? 48.845 118.372 77.497 1.00 11.17 ? 123 GLY M C 1 ATOM 969 O O . GLY A 1 123 ? 47.858 119.021 77.915 1.00 12.21 ? 123 GLY M O 1 ATOM 970 N N . LEU A 1 124 ? 49.096 118.230 76.199 1.00 10.08 ? 124 LEU M N 1 ATOM 971 C CA . LEU A 1 124 ? 48.258 118.863 75.211 1.00 10.42 ? 124 LEU M CA 1 ATOM 972 C C . LEU A 1 124 ? 46.854 118.372 75.228 1.00 9.65 ? 124 LEU M C 1 ATOM 973 O O . LEU A 1 124 ? 45.891 119.123 75.182 1.00 9.91 ? 124 LEU M O 1 ATOM 974 C CB . LEU A 1 124 ? 48.872 118.683 73.803 1.00 10.26 ? 124 LEU M CB 1 ATOM 975 C CG . LEU A 1 124 ? 48.078 119.202 72.654 1.00 12.06 ? 124 LEU M CG 1 ATOM 976 C CD1 . LEU A 1 124 ? 47.751 120.666 72.648 1.00 13.12 ? 124 LEU M CD1 1 ATOM 977 C CD2 . LEU A 1 124 ? 48.826 118.742 71.283 1.00 9.75 ? 124 LEU M CD2 1 ATOM 978 N N . ILE A 1 125 ? 46.699 117.050 75.209 1.00 9.38 ? 125 ILE M N 1 ATOM 979 C CA . ILE A 1 125 ? 45.419 116.415 75.175 1.00 8.83 ? 125 ILE M CA 1 ATOM 980 C C . ILE A 1 125 ? 44.623 116.780 76.421 1.00 11.29 ? 125 ILE M C 1 ATOM 981 O O . ILE A 1 125 ? 43.432 117.188 76.317 1.00 11.66 ? 125 ILE M O 1 ATOM 982 C CB . ILE A 1 125 ? 45.568 114.902 75.004 1.00 9.56 ? 125 ILE M CB 1 ATOM 983 C CG1 . ILE A 1 125 ? 46.087 114.563 73.606 1.00 10.13 ? 125 ILE M CG1 1 ATOM 984 C CG2 . ILE A 1 125 ? 44.178 114.173 75.299 1.00 12.38 ? 125 ILE M CG2 1 ATOM 985 C CD1 . ILE A 1 125 ? 46.666 113.120 73.482 1.00 12.06 ? 125 ILE M CD1 1 ATOM 986 N N . SER A 1 126 ? 45.295 116.708 77.557 1.00 10.98 ? 126 SER M N 1 ATOM 987 C CA . SER A 1 126 ? 44.584 117.079 78.808 1.00 13.26 ? 126 SER M CA 1 ATOM 988 C C . SER A 1 126 ? 44.148 118.574 78.764 1.00 12.98 ? 126 SER M C 1 ATOM 989 O O . SER A 1 126 ? 42.967 118.848 79.129 1.00 13.32 ? 126 SER M O 1 ATOM 990 C CB A SER A 1 126 ? 45.497 116.973 79.987 0.70 13.17 ? 126 SER M CB 1 ATOM 991 C CB B SER A 1 126 ? 45.489 116.786 79.993 0.30 13.12 ? 126 SER M CB 1 ATOM 992 O OG A SER A 1 126 ? 44.803 117.353 81.190 0.70 27.45 ? 126 SER M OG 1 ATOM 993 O OG B SER A 1 126 ? 45.648 115.377 80.173 0.30 18.41 ? 126 SER M OG 1 ATOM 994 N N . GLY A 1 127 ? 44.967 119.451 78.207 1.00 11.89 ? 127 GLY M N 1 ATOM 995 C CA . GLY A 1 127 ? 44.598 120.778 78.168 1.00 12.64 ? 127 GLY M CA 1 ATOM 996 C C . GLY A 1 127 ? 43.452 121.080 77.232 1.00 12.86 ? 127 GLY M C 1 ATOM 997 O O . GLY A 1 127 ? 42.610 121.933 77.463 1.00 13.33 ? 127 GLY M O 1 ATOM 998 N N . LEU A 1 128 ? 43.419 120.387 76.086 1.00 9.43 ? 128 LEU M N 1 ATOM 999 C CA . LEU A 1 128 ? 42.300 120.521 75.175 1.00 10.74 ? 128 LEU M CA 1 ATOM 1000 C C . LEU A 1 128 ? 41.008 120.098 75.864 1.00 10.53 ? 128 LEU M C 1 ATOM 1001 O O . LEU A 1 128 ? 39.975 120.757 75.662 1.00 12.07 ? 128 LEU M O 1 ATOM 1002 C CB . LEU A 1 128 ? 42.602 119.658 73.897 1.00 8.27 ? 128 LEU M CB 1 ATOM 1003 C CG . LEU A 1 128 ? 43.748 120.147 73.034 1.00 9.98 ? 128 LEU M CG 1 ATOM 1004 C CD1 . LEU A 1 128 ? 44.142 119.086 71.999 1.00 10.33 ? 128 LEU M CD1 1 ATOM 1005 C CD2 . LEU A 1 128 ? 43.336 121.387 72.294 1.00 10.65 ? 128 LEU M CD2 1 ATOM 1006 N N . ILE A 1 129 ? 41.009 118.904 76.441 1.00 11.14 ? 129 ILE M N 1 ATOM 1007 C CA . ILE A 1 129 ? 39.754 118.335 76.981 1.00 14.95 ? 129 ILE M CA 1 ATOM 1008 C C . ILE A 1 129 ? 39.306 119.292 78.063 1.00 15.40 ? 129 ILE M C 1 ATOM 1009 O O . ILE A 1 129 ? 38.081 119.514 78.212 1.00 17.38 ? 129 ILE M O 1 ATOM 1010 C CB . ILE A 1 129 ? 40.030 116.927 77.441 1.00 15.00 ? 129 ILE M CB 1 ATOM 1011 C CG1 . ILE A 1 129 ? 40.175 116.060 76.185 1.00 18.50 ? 129 ILE M CG1 1 ATOM 1012 C CG2 . ILE A 1 129 ? 38.890 116.384 78.440 1.00 21.91 ? 129 ILE M CG2 1 ATOM 1013 C CD1 . ILE A 1 129 ? 40.582 114.682 76.407 1.00 23.02 ? 129 ILE M CD1 1 ATOM 1014 N N . LYS A 1 130 ? 40.239 119.806 78.827 1.00 14.79 ? 130 LYS M N 1 ATOM 1015 C CA . LYS A 1 130 ? 39.882 120.752 79.937 1.00 17.85 ? 130 LYS M CA 1 ATOM 1016 C C . LYS A 1 130 ? 39.166 121.974 79.462 1.00 18.43 ? 130 LYS M C 1 ATOM 1017 O O . LYS A 1 130 ? 38.403 122.604 80.239 1.00 20.03 ? 130 LYS M O 1 ATOM 1018 C CB . LYS A 1 130 ? 41.049 120.993 80.815 1.00 20.43 ? 130 LYS M CB 1 ATOM 1019 C CG . LYS A 1 130 ? 41.257 119.800 81.928 1.00 28.07 ? 130 LYS M CG 1 ATOM 1020 C CD . LYS A 1 130 ? 41.918 118.432 81.660 1.00 36.52 ? 130 LYS M CD 1 ATOM 1021 C CE . LYS A 1 130 ? 41.212 117.318 80.904 1.00 32.57 ? 130 LYS M CE 1 ATOM 1022 N NZ . LYS A 1 130 ? 41.837 115.953 80.927 1.00 106.89 ? 130 LYS M NZ 1 ATOM 1023 N N . LYS A 1 131 ? 39.305 122.359 78.215 1.00 14.87 ? 131 LYS M N 1 ATOM 1024 C CA . LYS A 1 131 ? 38.696 123.524 77.631 1.00 14.19 ? 131 LYS M CA 1 ATOM 1025 C C . LYS A 1 131 ? 37.524 123.111 76.683 1.00 16.91 ? 131 LYS M C 1 ATOM 1026 O O . LYS A 1 131 ? 36.970 123.918 75.932 1.00 17.12 ? 131 LYS M O 1 ATOM 1027 C CB . LYS A 1 131 ? 39.681 124.394 76.947 1.00 15.47 ? 131 LYS M CB 1 ATOM 1028 C CG . LYS A 1 131 ? 40.640 125.034 77.871 1.00 19.22 ? 131 LYS M CG 1 ATOM 1029 C CD . LYS A 1 131 ? 39.893 126.212 78.594 1.00 28.25 ? 131 LYS M CD 1 ATOM 1030 C CE . LYS A 1 131 ? 40.614 126.717 79.773 1.00 30.03 ? 131 LYS M CE 1 ATOM 1031 N NZ . LYS A 1 131 ? 39.697 127.817 80.369 1.00 37.69 ? 131 LYS M NZ 1 ATOM 1032 N N . GLY A 1 132 ? 37.112 121.845 76.736 1.00 13.51 ? 132 GLY M N 1 ATOM 1033 C CA . GLY A 1 132 ? 36.012 121.377 75.922 1.00 13.41 ? 132 GLY M CA 1 ATOM 1034 C C . GLY A 1 132 ? 36.178 121.159 74.469 1.00 15.13 ? 132 GLY M C 1 ATOM 1035 O O . GLY A 1 132 ? 35.261 121.330 73.631 1.00 16.34 ? 132 GLY M O 1 ATOM 1036 N N . ILE A 1 133 ? 37.438 120.941 74.139 1.00 12.51 ? 133 ILE M N 1 ATOM 1037 C CA . ILE A 1 133 ? 37.832 120.758 72.737 1.00 11.18 ? 133 ILE M CA 1 ATOM 1038 C C . ILE A 1 133 ? 38.073 119.272 72.512 1.00 12.62 ? 133 ILE M C 1 ATOM 1039 O O . ILE A 1 133 ? 38.874 118.681 73.193 1.00 15.09 ? 133 ILE M O 1 ATOM 1040 C CB . ILE A 1 133 ? 39.138 121.553 72.480 1.00 11.54 ? 133 ILE M CB 1 ATOM 1041 C CG1 . ILE A 1 133 ? 39.005 123.020 72.777 1.00 13.12 ? 133 ILE M CG1 1 ATOM 1042 C CG2 . ILE A 1 133 ? 39.565 121.421 71.001 1.00 11.55 ? 133 ILE M CG2 1 ATOM 1043 C CD1 . ILE A 1 133 ? 40.303 123.730 73.130 1.00 13.36 ? 133 ILE M CD1 1 ATOM 1044 N N . THR A 1 134 ? 37.424 118.688 71.498 1.00 9.90 ? 134 THR M N 1 ATOM 1045 C CA . THR A 1 134 ? 37.571 117.338 71.032 1.00 9.23 ? 134 THR M CA 1 ATOM 1046 C C . THR A 1 134 ? 38.826 117.187 70.191 1.00 10.01 ? 134 THR M C 1 ATOM 1047 O O . THR A 1 134 ? 38.855 117.792 69.150 1.00 11.42 ? 134 THR M O 1 ATOM 1048 C CB . THR A 1 134 ? 36.426 116.917 70.245 1.00 10.76 ? 134 THR M CB 1 ATOM 1049 O OG1 . THR A 1 134 ? 35.206 116.962 71.118 1.00 15.85 ? 134 THR M OG1 1 ATOM 1050 C CG2 . THR A 1 134 ? 36.542 115.408 69.857 1.00 13.19 ? 134 THR M CG2 1 ATOM 1051 N N . PRO A 1 135 ? 39.817 116.392 70.646 1.00 10.53 ? 135 PRO M N 1 ATOM 1052 C CA . PRO A 1 135 ? 40.943 116.177 69.760 1.00 10.00 ? 135 PRO M CA 1 ATOM 1053 C C . PRO A 1 135 ? 40.638 115.192 68.620 1.00 10.97 ? 135 PRO M C 1 ATOM 1054 O O . PRO A 1 135 ? 39.925 114.150 68.819 1.00 10.86 ? 135 PRO M O 1 ATOM 1055 C CB . PRO A 1 135 ? 41.939 115.546 70.624 1.00 12.20 ? 135 PRO M CB 1 ATOM 1056 C CG . PRO A 1 135 ? 41.373 115.487 71.979 1.00 14.99 ? 135 PRO M CG 1 ATOM 1057 C CD . PRO A 1 135 ? 40.022 115.785 71.997 1.00 12.10 ? 135 PRO M CD 1 ATOM 1058 N N . PHE A 1 136 ? 41.127 115.471 67.407 1.00 7.72 ? 136 PHE M N 1 ATOM 1059 C CA . PHE A 1 136 ? 41.085 114.589 66.272 1.00 7.51 ? 136 PHE M CA 1 ATOM 1060 C C . PHE A 1 136 ? 42.583 114.350 65.946 1.00 8.88 ? 136 PHE M C 1 ATOM 1061 O O . PHE A 1 136 ? 43.248 115.310 65.554 1.00 10.78 ? 136 PHE M O 1 ATOM 1062 C CB . PHE A 1 136 ? 40.434 115.233 65.096 1.00 7.66 ? 136 PHE M CB 1 ATOM 1063 C CG . PHE A 1 136 ? 38.915 115.313 65.152 1.00 9.98 ? 136 PHE M CG 1 ATOM 1064 C CD1 . PHE A 1 136 ? 38.328 116.242 66.033 1.00 10.26 ? 136 PHE M CD1 1 ATOM 1065 C CD2 . PHE A 1 136 ? 38.112 114.530 64.393 1.00 11.84 ? 136 PHE M CD2 1 ATOM 1066 C CE1 . PHE A 1 136 ? 36.942 116.306 66.164 1.00 12.56 ? 136 PHE M CE1 1 ATOM 1067 C CE2 . PHE A 1 136 ? 36.736 114.591 64.581 1.00 14.48 ? 136 PHE M CE2 1 ATOM 1068 C CZ . PHE A 1 136 ? 36.194 115.500 65.403 1.00 13.99 ? 136 PHE M CZ 1 ATOM 1069 N N . VAL A 1 137 ? 43.128 113.165 66.199 1.00 7.95 ? 137 VAL M N 1 ATOM 1070 C CA . VAL A 1 137 ? 44.582 112.972 66.224 1.00 7.48 ? 137 VAL M CA 1 ATOM 1071 C C . VAL A 1 137 ? 45.020 112.171 65.036 1.00 8.67 ? 137 VAL M C 1 ATOM 1072 O O . VAL A 1 137 ? 44.653 111.029 64.883 1.00 9.05 ? 137 VAL M O 1 ATOM 1073 C CB . VAL A 1 137 ? 45.039 112.358 67.527 1.00 8.04 ? 137 VAL M CB 1 ATOM 1074 C CG1 . VAL A 1 137 ? 46.570 112.180 67.515 1.00 11.66 ? 137 VAL M CG1 1 ATOM 1075 C CG2 . VAL A 1 137 ? 44.538 113.238 68.728 1.00 9.96 ? 137 VAL M CG2 1 ATOM 1076 N N . THR A 1 138 ? 45.873 112.822 64.219 1.00 7.51 ? 138 THR M N 1 ATOM 1077 C CA . THR A 1 138 ? 46.484 112.147 63.059 1.00 6.95 ? 138 THR M CA 1 ATOM 1078 C C . THR A 1 138 ? 47.715 111.364 63.482 1.00 7.84 ? 138 THR M C 1 ATOM 1079 O O . THR A 1 138 ? 48.660 111.942 64.077 1.00 8.55 ? 138 THR M O 1 ATOM 1080 C CB . THR A 1 138 ? 46.853 113.099 61.951 1.00 7.85 ? 138 THR M CB 1 ATOM 1081 O OG1 . THR A 1 138 ? 45.836 113.989 61.681 1.00 10.05 ? 138 THR M OG1 1 ATOM 1082 C CG2 . THR A 1 138 ? 47.373 112.427 60.670 1.00 9.69 ? 138 THR M CG2 1 ATOM 1083 N N . LEU A 1 139 ? 47.768 110.055 63.232 1.00 7.38 ? 139 LEU M N 1 ATOM 1084 C CA . LEU A 1 139 ? 48.952 109.242 63.625 1.00 6.65 ? 139 LEU M CA 1 ATOM 1085 C C . LEU A 1 139 ? 50.154 109.546 62.738 1.00 8.93 ? 139 LEU M C 1 ATOM 1086 O O . LEU A 1 139 ? 51.263 109.641 63.198 1.00 8.60 ? 139 LEU M O 1 ATOM 1087 C CB . LEU A 1 139 ? 48.610 107.725 63.497 1.00 7.29 ? 139 LEU M CB 1 ATOM 1088 C CG . LEU A 1 139 ? 47.635 107.290 64.502 1.00 9.42 ? 139 LEU M CG 1 ATOM 1089 C CD1 . LEU A 1 139 ? 47.180 105.843 64.072 1.00 10.34 ? 139 LEU M CD1 1 ATOM 1090 C CD2 . LEU A 1 139 ? 48.269 107.220 65.957 1.00 10.68 ? 139 LEU M CD2 1 ATOM 1091 N N . PHE A 1 140 ? 49.898 109.776 61.444 1.00 9.27 ? 140 PHE M N 1 ATOM 1092 C CA . PHE A 1 140 ? 50.965 109.903 60.473 1.00 9.37 ? 140 PHE M CA 1 ATOM 1093 C C . PHE A 1 140 ? 50.616 111.036 59.528 1.00 9.33 ? 140 PHE M C 1 ATOM 1094 O O . PHE A 1 140 ? 49.952 110.873 58.533 1.00 9.95 ? 140 PHE M O 1 ATOM 1095 C CB . PHE A 1 140 ? 51.254 108.591 59.744 1.00 8.68 ? 140 PHE M CB 1 ATOM 1096 C CG . PHE A 1 140 ? 52.412 108.643 58.770 1.00 9.62 ? 140 PHE M CG 1 ATOM 1097 C CD1 . PHE A 1 140 ? 53.671 108.834 59.254 1.00 11.97 ? 140 PHE M CD1 1 ATOM 1098 C CD2 . PHE A 1 140 ? 52.203 108.622 57.434 1.00 11.85 ? 140 PHE M CD2 1 ATOM 1099 C CE1 . PHE A 1 140 ? 54.695 108.956 58.375 1.00 11.36 ? 140 PHE M CE1 1 ATOM 1100 C CE2 . PHE A 1 140 ? 53.260 108.774 56.504 1.00 11.99 ? 140 PHE M CE2 1 ATOM 1101 C CZ . PHE A 1 140 ? 54.509 108.890 57.046 1.00 12.58 ? 140 PHE M CZ 1 ATOM 1102 N N . HIS A 1 141 ? 51.231 112.172 59.750 1.00 8.07 ? 141 HIS M N 1 ATOM 1103 C CA . HIS A 1 141 ? 51.179 113.300 58.850 1.00 8.78 ? 141 HIS M CA 1 ATOM 1104 C C . HIS A 1 141 ? 52.545 113.537 58.146 1.00 9.73 ? 141 HIS M C 1 ATOM 1105 O O . HIS A 1 141 ? 53.112 114.602 58.225 1.00 9.44 ? 141 HIS M O 1 ATOM 1106 C CB . HIS A 1 141 ? 50.653 114.531 59.552 1.00 8.20 ? 141 HIS M CB 1 ATOM 1107 C CG . HIS A 1 141 ? 50.053 115.568 58.667 1.00 9.43 ? 141 HIS M CG 1 ATOM 1108 N ND1 . HIS A 1 141 ? 48.753 116.060 58.867 1.00 10.97 ? 141 HIS M ND1 1 ATOM 1109 C CD2 . HIS A 1 141 ? 50.569 116.276 57.663 1.00 9.78 ? 141 HIS M CD2 1 ATOM 1110 C CE1 . HIS A 1 141 ? 48.543 117.020 58.005 1.00 8.25 ? 141 HIS M CE1 1 ATOM 1111 N NE2 . HIS A 1 141 ? 49.609 117.165 57.228 1.00 10.69 ? 141 HIS M NE2 1 ATOM 1112 N N . TRP A 1 142 ? 52.993 112.476 57.518 1.00 10.90 ? 142 TRP M N 1 ATOM 1113 C CA . TRP A 1 142 ? 54.095 112.454 56.548 1.00 8.92 ? 142 TRP M CA 1 ATOM 1114 C C . TRP A 1 142 ? 55.504 112.362 57.178 1.00 9.22 ? 142 TRP M C 1 ATOM 1115 O O . TRP A 1 142 ? 56.498 112.129 56.437 1.00 9.99 ? 142 TRP M O 1 ATOM 1116 C CB . TRP A 1 142 ? 54.038 113.608 55.604 1.00 8.98 ? 142 TRP M CB 1 ATOM 1117 C CG . TRP A 1 142 ? 52.704 113.723 54.811 1.00 7.46 ? 142 TRP M CG 1 ATOM 1118 C CD1 . TRP A 1 142 ? 51.720 112.772 54.693 1.00 10.34 ? 142 TRP M CD1 1 ATOM 1119 C CD2 . TRP A 1 142 ? 52.363 114.800 53.956 1.00 8.77 ? 142 TRP M CD2 1 ATOM 1120 N NE1 . TRP A 1 142 ? 50.745 113.285 53.823 1.00 10.38 ? 142 TRP M NE1 1 ATOM 1121 C CE2 . TRP A 1 142 ? 51.126 114.477 53.348 1.00 11.87 ? 142 TRP M CE2 1 ATOM 1122 C CE3 . TRP A 1 142 ? 52.975 115.988 53.613 1.00 13.52 ? 142 TRP M CE3 1 ATOM 1123 C CZ2 . TRP A 1 142 ? 50.495 115.377 52.503 1.00 11.22 ? 142 TRP M CZ2 1 ATOM 1124 C CZ3 . TRP A 1 142 ? 52.381 116.835 52.688 1.00 16.24 ? 142 TRP M CZ3 1 ATOM 1125 C CH2 . TRP A 1 142 ? 51.151 116.500 52.153 1.00 14.95 ? 142 TRP M CH2 1 ATOM 1126 N N . ASP A 1 143 ? 55.602 112.576 58.477 1.00 8.07 ? 143 ASP M N 1 ATOM 1127 C CA . ASP A 1 143 ? 56.901 112.741 59.166 1.00 8.23 ? 143 ASP M CA 1 ATOM 1128 C C . ASP A 1 143 ? 57.469 111.410 59.625 1.00 9.19 ? 143 ASP M C 1 ATOM 1129 O O . ASP A 1 143 ? 57.613 111.125 60.814 1.00 10.07 ? 143 ASP M O 1 ATOM 1130 C CB . ASP A 1 143 ? 56.758 113.752 60.234 1.00 9.06 ? 143 ASP M CB 1 ATOM 1131 C CG . ASP A 1 143 ? 55.665 113.457 61.255 1.00 12.62 ? 143 ASP M CG 1 ATOM 1132 O OD1 . ASP A 1 143 ? 54.617 112.900 60.902 1.00 10.90 ? 143 ASP M OD1 1 ATOM 1133 O OD2 . ASP A 1 143 ? 55.798 114.050 62.398 1.00 11.48 ? 143 ASP M OD2 1 ATOM 1134 N N . LEU A 1 144 ? 57.825 110.520 58.667 1.00 7.77 ? 144 LEU M N 1 ATOM 1135 C CA . LEU A 1 144 ? 58.338 109.168 59.016 1.00 7.53 ? 144 LEU M CA 1 ATOM 1136 C C . LEU A 1 144 ? 59.718 109.363 59.632 1.00 7.28 ? 144 LEU M C 1 ATOM 1137 O O . LEU A 1 144 ? 60.572 109.967 59.042 1.00 7.85 ? 144 LEU M O 1 ATOM 1138 C CB . LEU A 1 144 ? 58.451 108.399 57.704 1.00 7.71 ? 144 LEU M CB 1 ATOM 1139 C CG . LEU A 1 144 ? 58.901 106.996 57.915 1.00 8.07 ? 144 LEU M CG 1 ATOM 1140 C CD1 . LEU A 1 144 ? 57.756 106.129 58.484 1.00 12.14 ? 144 LEU M CD1 1 ATOM 1141 C CD2 . LEU A 1 144 ? 59.247 106.313 56.531 1.00 9.38 ? 144 LEU M CD2 1 ATOM 1142 N N . PRO A 1 145 ? 60.034 108.616 60.683 1.00 8.26 ? 145 PRO M N 1 ATOM 1143 C CA . PRO A 1 145 ? 61.418 108.547 61.223 1.00 8.24 ? 145 PRO M CA 1 ATOM 1144 C C . PRO A 1 145 ? 62.412 108.240 60.125 1.00 9.20 ? 145 PRO M C 1 ATOM 1145 O O . PRO A 1 145 ? 62.231 107.304 59.328 1.00 8.38 ? 145 PRO M O 1 ATOM 1146 C CB . PRO A 1 145 ? 61.376 107.465 62.319 1.00 9.30 ? 145 PRO M CB 1 ATOM 1147 C CG . PRO A 1 145 ? 59.976 107.577 62.757 1.00 10.54 ? 145 PRO M CG 1 ATOM 1148 C CD . PRO A 1 145 ? 59.098 107.862 61.537 1.00 7.98 ? 145 PRO M CD 1 ATOM 1149 N N . GLN A 1 146 ? 63.483 109.030 60.072 1.00 7.26 ? 146 GLN M N 1 ATOM 1150 C CA . GLN A 1 146 ? 64.439 108.909 58.996 1.00 8.83 ? 146 GLN M CA 1 ATOM 1151 C C . GLN A 1 146 ? 65.093 107.543 58.974 1.00 8.14 ? 146 GLN M C 1 ATOM 1152 O O . GLN A 1 146 ? 65.377 106.946 57.898 1.00 8.06 ? 146 GLN M O 1 ATOM 1153 C CB . GLN A 1 146 ? 65.529 109.973 59.107 1.00 9.02 ? 146 GLN M CB 1 ATOM 1154 C CG . GLN A 1 146 ? 66.557 109.977 57.936 1.00 9.51 ? 146 GLN M CG 1 ATOM 1155 C CD . GLN A 1 146 ? 65.991 110.317 56.567 1.00 13.89 ? 146 GLN M CD 1 ATOM 1156 O OE1 . GLN A 1 146 ? 65.344 111.299 56.432 1.00 15.45 ? 146 GLN M OE1 1 ATOM 1157 N NE2 . GLN A 1 146 ? 66.281 109.515 55.550 1.00 13.68 ? 146 GLN M NE2 1 ATOM 1158 N N . THR A 1 147 ? 65.327 106.965 60.157 1.00 9.11 ? 147 THR M N 1 ATOM 1159 C CA . THR A 1 147 ? 65.883 105.640 60.283 1.00 9.33 ? 147 THR M CA 1 ATOM 1160 C C . THR A 1 147 ? 65.129 104.634 59.425 1.00 9.38 ? 147 THR M C 1 ATOM 1161 O O . THR A 1 147 ? 65.707 103.735 58.830 1.00 9.54 ? 147 THR M O 1 ATOM 1162 C CB . THR A 1 147 ? 65.953 105.190 61.770 1.00 8.68 ? 147 THR M CB 1 ATOM 1163 O OG1 . THR A 1 147 ? 66.540 103.831 61.905 1.00 17.78 ? 147 THR M OG1 1 ATOM 1164 C CG2 . THR A 1 147 ? 64.613 105.249 62.514 1.00 11.15 ? 147 THR M CG2 1 ATOM 1165 N N . LEU A 1 148 ? 63.766 104.673 59.413 1.00 7.49 ? 148 LEU M N 1 ATOM 1166 C CA . LEU A 1 148 ? 62.969 103.699 58.658 1.00 8.61 ? 148 LEU M CA 1 ATOM 1167 C C . LEU A 1 148 ? 63.136 103.930 57.165 1.00 8.85 ? 148 LEU M C 1 ATOM 1168 O O . LEU A 1 148 ? 63.115 102.949 56.393 1.00 8.38 ? 148 LEU M O 1 ATOM 1169 C CB . LEU A 1 148 ? 61.504 103.778 59.106 1.00 8.80 ? 148 LEU M CB 1 ATOM 1170 C CG . LEU A 1 148 ? 61.293 103.456 60.607 1.00 9.45 ? 148 LEU M CG 1 ATOM 1171 C CD1 . LEU A 1 148 ? 59.736 103.568 60.916 1.00 10.29 ? 148 LEU M CD1 1 ATOM 1172 C CD2 . LEU A 1 148 ? 61.973 102.120 61.115 1.00 10.28 ? 148 LEU M CD2 1 ATOM 1173 N N . GLN A 1 149 ? 63.227 105.156 56.713 1.00 7.57 ? 149 GLN M N 1 ATOM 1174 C CA . GLN A 1 149 ? 63.492 105.444 55.319 1.00 7.16 ? 149 GLN M CA 1 ATOM 1175 C C . GLN A 1 149 ? 64.870 104.914 54.944 1.00 7.93 ? 149 GLN M C 1 ATOM 1176 O O . GLN A 1 149 ? 65.105 104.371 53.856 1.00 8.82 ? 149 GLN M O 1 ATOM 1177 C CB . GLN A 1 149 ? 63.342 106.915 54.984 1.00 7.03 ? 149 GLN M CB 1 ATOM 1178 C CG . GLN A 1 149 ? 63.207 107.170 53.509 1.00 7.31 ? 149 GLN M CG 1 ATOM 1179 C CD . GLN A 1 149 ? 61.836 106.771 52.965 1.00 8.27 ? 149 GLN M CD 1 ATOM 1180 O OE1 . GLN A 1 149 ? 60.801 106.976 53.659 1.00 9.39 ? 149 GLN M OE1 1 ATOM 1181 N NE2 . GLN A 1 149 ? 61.791 106.276 51.735 1.00 8.53 ? 149 GLN M NE2 1 ATOM 1182 N N . ASP A 1 150 ? 65.843 105.055 55.830 1.00 9.17 ? 150 ASP M N 1 ATOM 1183 C CA . ASP A 1 150 ? 67.205 104.622 55.547 1.00 8.62 ? 150 ASP M CA 1 ATOM 1184 C C . ASP A 1 150 ? 67.339 103.120 55.655 1.00 9.93 ? 150 ASP M C 1 ATOM 1185 O O . ASP A 1 150 ? 68.122 102.499 54.887 1.00 9.27 ? 150 ASP M O 1 ATOM 1186 C CB . ASP A 1 150 ? 68.194 105.330 56.398 1.00 8.60 ? 150 ASP M CB 1 ATOM 1187 C CG . ASP A 1 150 ? 68.398 106.789 55.978 1.00 11.51 ? 150 ASP M CG 1 ATOM 1188 O OD1 . ASP A 1 150 ? 68.000 107.219 54.755 1.00 13.73 ? 150 ASP M OD1 1 ATOM 1189 O OD2 . ASP A 1 150 ? 68.843 107.679 56.762 1.00 14.34 ? 150 ASP M OD2 1 ATOM 1190 N N . GLU A 1 151 ? 66.627 102.469 56.567 1.00 8.58 ? 151 GLU M N 1 ATOM 1191 C CA . GLU A 1 151 ? 66.663 101.002 56.652 1.00 8.44 ? 151 GLU M CA 1 ATOM 1192 C C . GLU A 1 151 ? 66.107 100.301 55.455 1.00 9.23 ? 151 GLU M C 1 ATOM 1193 O O . GLU A 1 151 ? 66.669 99.310 54.968 1.00 12.78 ? 151 GLU M O 1 ATOM 1194 C CB . GLU A 1 151 ? 65.952 100.464 57.930 1.00 10.81 ? 151 GLU M CB 1 ATOM 1195 C CG . GLU A 1 151 ? 66.687 100.719 59.252 1.00 12.74 ? 151 GLU M CG 1 ATOM 1196 C CD . GLU A 1 151 ? 66.015 100.039 60.445 1.00 18.42 ? 151 GLU M CD 1 ATOM 1197 O OE1 . GLU A 1 151 ? 66.189 98.805 60.669 1.00 28.22 ? 151 GLU M OE1 1 ATOM 1198 O OE2 . GLU A 1 151 ? 65.294 100.709 61.089 1.00 19.98 ? 151 GLU M OE2 1 ATOM 1199 N N . TYR A 1 152 ? 64.899 100.708 55.026 1.00 9.11 ? 152 TYR M N 1 ATOM 1200 C CA . TYR A 1 152 ? 64.132 99.954 54.042 1.00 8.82 ? 152 TYR M CA 1 ATOM 1201 C C . TYR A 1 152 ? 63.322 100.820 53.139 1.00 8.71 ? 152 TYR M C 1 ATOM 1202 O O . TYR A 1 152 ? 62.474 100.281 52.395 1.00 10.92 ? 152 TYR M O 1 ATOM 1203 C CB . TYR A 1 152 ? 63.223 98.910 54.706 1.00 10.79 ? 152 TYR M CB 1 ATOM 1204 C CG . TYR A 1 152 ? 62.268 99.354 55.791 1.00 8.86 ? 152 TYR M CG 1 ATOM 1205 C CD1 . TYR A 1 152 ? 61.116 99.993 55.488 1.00 9.63 ? 152 TYR M CD1 1 ATOM 1206 C CD2 . TYR A 1 152 ? 62.494 99.040 57.130 1.00 8.89 ? 152 TYR M CD2 1 ATOM 1207 C CE1 . TYR A 1 152 ? 60.276 100.356 56.501 1.00 9.70 ? 152 TYR M CE1 1 ATOM 1208 C CE2 . TYR A 1 152 ? 61.637 99.389 58.109 1.00 10.16 ? 152 TYR M CE2 1 ATOM 1209 C CZ . TYR A 1 152 ? 60.503 100.057 57.798 1.00 8.93 ? 152 TYR M CZ 1 ATOM 1210 O OH . TYR A 1 152 ? 59.537 100.366 58.721 1.00 9.94 ? 152 TYR M OH 1 ATOM 1211 N N . GLU A 1 153 ? 63.598 102.114 53.059 1.00 8.36 ? 153 GLU M N 1 ATOM 1212 C CA . GLU A 1 153 ? 62.911 103.030 52.188 1.00 7.73 ? 153 GLU M CA 1 ATOM 1213 C C . GLU A 1 153 ? 61.454 103.122 52.586 1.00 8.96 ? 153 GLU M C 1 ATOM 1214 O O . GLU A 1 153 ? 60.571 103.395 51.738 1.00 8.66 ? 153 GLU M O 1 ATOM 1215 C CB . GLU A 1 153 ? 63.126 102.824 50.680 1.00 10.36 ? 153 GLU M CB 1 ATOM 1216 C CG . GLU A 1 153 ? 64.636 103.100 50.366 1.00 11.18 ? 153 GLU M CG 1 ATOM 1217 C CD . GLU A 1 153 ? 65.064 104.535 50.463 1.00 13.89 ? 153 GLU M CD 1 ATOM 1218 O OE1 . GLU A 1 153 ? 64.307 105.564 50.351 1.00 10.56 ? 153 GLU M OE1 1 ATOM 1219 O OE2 . GLU A 1 153 ? 66.311 104.781 50.542 1.00 16.43 ? 153 GLU M OE2 1 ATOM 1220 N N . GLY A 1 154 ? 61.152 103.085 53.896 1.00 7.90 ? 154 GLY M N 1 ATOM 1221 C CA . GLY A 1 154 ? 59.883 103.518 54.370 1.00 8.21 ? 154 GLY M CA 1 ATOM 1222 C C . GLY A 1 154 ? 58.693 102.786 53.772 1.00 7.97 ? 154 GLY M C 1 ATOM 1223 O O . GLY A 1 154 ? 58.689 101.546 53.691 1.00 8.79 ? 154 GLY M O 1 ATOM 1224 N N . PHE A 1 155 ? 57.718 103.560 53.312 1.00 7.61 ? 155 PHE M N 1 ATOM 1225 C CA . PHE A 1 155 ? 56.540 102.988 52.769 1.00 9.16 ? 155 PHE M CA 1 ATOM 1226 C C . PHE A 1 155 ? 56.752 102.231 51.445 1.00 9.89 ? 155 PHE M C 1 ATOM 1227 O O . PHE A 1 155 ? 55.834 101.607 50.926 1.00 10.41 ? 155 PHE M O 1 ATOM 1228 C CB . PHE A 1 155 ? 55.385 103.974 52.638 1.00 10.09 ? 155 PHE M CB 1 ATOM 1229 C CG . PHE A 1 155 ? 54.622 104.188 53.938 1.00 9.02 ? 155 PHE M CG 1 ATOM 1230 C CD1 . PHE A 1 155 ? 55.089 105.113 54.880 1.00 8.93 ? 155 PHE M CD1 1 ATOM 1231 C CD2 . PHE A 1 155 ? 53.491 103.501 54.205 1.00 10.24 ? 155 PHE M CD2 1 ATOM 1232 C CE1 . PHE A 1 155 ? 54.437 105.247 56.042 1.00 10.80 ? 155 PHE M CE1 1 ATOM 1233 C CE2 . PHE A 1 155 ? 52.808 103.648 55.404 1.00 9.34 ? 155 PHE M CE2 1 ATOM 1234 C CZ . PHE A 1 155 ? 53.262 104.579 56.303 1.00 10.94 ? 155 PHE M CZ 1 ATOM 1235 N N . LEU A 1 156 ? 57.974 102.264 50.870 1.00 9.70 ? 156 LEU M N 1 ATOM 1236 C CA . LEU A 1 156 ? 58.277 101.436 49.717 1.00 8.43 ? 156 LEU M CA 1 ATOM 1237 C C . LEU A 1 156 ? 58.350 100.002 50.030 1.00 10.79 ? 156 LEU M C 1 ATOM 1238 O O . LEU A 1 156 ? 58.246 99.155 49.104 1.00 11.76 ? 156 LEU M O 1 ATOM 1239 C CB . LEU A 1 156 ? 59.556 101.989 49.050 1.00 10.83 ? 156 LEU M CB 1 ATOM 1240 C CG . LEU A 1 156 ? 59.972 101.405 47.728 1.00 11.98 ? 156 LEU M CG 1 ATOM 1241 C CD1 . LEU A 1 156 ? 58.873 101.833 46.704 1.00 10.51 ? 156 LEU M CD1 1 ATOM 1242 C CD2 . LEU A 1 156 ? 61.327 102.044 47.367 1.00 12.25 ? 156 LEU M CD2 1 ATOM 1243 N N . ASP A 1 157 ? 58.519 99.619 51.291 1.00 8.21 ? 157 ASP M N 1 ATOM 1244 C CA . ASP A 1 157 ? 58.764 98.266 51.693 1.00 8.96 ? 157 ASP M CA 1 ATOM 1245 C C . ASP A 1 157 ? 57.677 97.776 52.610 1.00 9.89 ? 157 ASP M C 1 ATOM 1246 O O . ASP A 1 157 ? 57.168 98.547 53.488 1.00 11.44 ? 157 ASP M O 1 ATOM 1247 C CB . ASP A 1 157 ? 60.080 98.199 52.446 1.00 9.91 ? 157 ASP M CB 1 ATOM 1248 C CG . ASP A 1 157 ? 60.596 96.789 52.646 1.00 14.35 ? 157 ASP M CG 1 ATOM 1249 O OD1 . ASP A 1 157 ? 60.160 96.016 53.522 1.00 14.78 ? 157 ASP M OD1 1 ATOM 1250 O OD2 . ASP A 1 157 ? 61.393 96.379 51.740 1.00 20.71 ? 157 ASP M OD2 1 ATOM 1251 N N . PRO A 1 158 ? 57.265 96.513 52.494 1.00 11.31 ? 158 PRO M N 1 ATOM 1252 C CA . PRO A 1 158 ? 56.244 95.983 53.395 1.00 11.95 ? 158 PRO M CA 1 ATOM 1253 C C . PRO A 1 158 ? 56.594 95.952 54.898 1.00 11.95 ? 158 PRO M C 1 ATOM 1254 O O . PRO A 1 158 ? 55.680 95.821 55.751 1.00 11.73 ? 158 PRO M O 1 ATOM 1255 C CB . PRO A 1 158 ? 55.997 94.557 52.864 1.00 16.12 ? 158 PRO M CB 1 ATOM 1256 C CG . PRO A 1 158 ? 57.064 94.194 52.104 1.00 15.34 ? 158 PRO M CG 1 ATOM 1257 C CD . PRO A 1 158 ? 57.678 95.505 51.494 1.00 12.84 ? 158 PRO M CD 1 ATOM 1258 N N . GLN A 1 159 ? 57.871 96.115 55.239 1.00 11.22 ? 159 GLN M N 1 ATOM 1259 C CA . GLN A 1 159 ? 58.286 96.223 56.641 1.00 11.31 ? 159 GLN M CA 1 ATOM 1260 C C . GLN A 1 159 ? 57.640 97.389 57.327 1.00 11.27 ? 159 GLN M C 1 ATOM 1261 O O . GLN A 1 159 ? 57.523 97.424 58.546 1.00 10.65 ? 159 GLN M O 1 ATOM 1262 C CB . GLN A 1 159 ? 59.809 96.341 56.730 1.00 12.40 ? 159 GLN M CB 1 ATOM 1263 C CG . GLN A 1 159 ? 60.489 95.032 56.519 1.00 16.07 ? 159 GLN M CG 1 ATOM 1264 C CD . GLN A 1 159 ? 61.984 95.185 56.320 1.00 21.38 ? 159 GLN M CD 1 ATOM 1265 O OE1 . GLN A 1 159 ? 62.749 95.339 57.265 1.00 32.23 ? 159 GLN M OE1 1 ATOM 1266 N NE2 . GLN A 1 159 ? 62.362 95.302 55.105 1.00 35.90 ? 159 GLN M NE2 1 ATOM 1267 N N . ILE A 1 160 ? 57.182 98.388 56.560 1.00 9.43 ? 160 ILE M N 1 ATOM 1268 C CA . ILE A 1 160 ? 56.547 99.528 57.213 1.00 8.56 ? 160 ILE M CA 1 ATOM 1269 C C . ILE A 1 160 ? 55.334 99.079 57.965 1.00 9.81 ? 160 ILE M C 1 ATOM 1270 O O . ILE A 1 160 ? 54.889 99.761 58.886 1.00 9.59 ? 160 ILE M O 1 ATOM 1271 C CB . ILE A 1 160 ? 56.153 100.619 56.136 1.00 8.84 ? 160 ILE M CB 1 ATOM 1272 C CG1 . ILE A 1 160 ? 55.785 101.923 56.765 1.00 9.67 ? 160 ILE M CG1 1 ATOM 1273 C CG2 . ILE A 1 160 ? 55.053 100.174 55.215 1.00 9.97 ? 160 ILE M CG2 1 ATOM 1274 C CD1 . ILE A 1 160 ? 56.943 102.566 57.527 1.00 10.19 ? 160 ILE M CD1 1 ATOM 1275 N N . ILE A 1 161 ? 54.596 98.035 57.515 1.00 8.81 ? 161 ILE M N 1 ATOM 1276 C CA . ILE A 1 161 ? 53.307 97.734 58.094 1.00 9.99 ? 161 ILE M CA 1 ATOM 1277 C C . ILE A 1 161 ? 53.409 97.410 59.568 1.00 10.00 ? 161 ILE M C 1 ATOM 1278 O O . ILE A 1 161 ? 52.697 98.010 60.389 1.00 12.24 ? 161 ILE M O 1 ATOM 1279 C CB . ILE A 1 161 ? 52.627 96.587 57.275 1.00 10.28 ? 161 ILE M CB 1 ATOM 1280 C CG1 . ILE A 1 161 ? 52.310 97.057 55.862 1.00 13.54 ? 161 ILE M CG1 1 ATOM 1281 C CG2 . ILE A 1 161 ? 51.401 96.075 58.025 1.00 11.57 ? 161 ILE M CG2 1 ATOM 1282 C CD1 . ILE A 1 161 ? 52.193 95.875 54.857 1.00 15.22 ? 161 ILE M CD1 1 ATOM 1283 N N . ASP A 1 162 ? 54.346 96.544 59.944 1.00 12.32 ? 162 ASP M N 1 ATOM 1284 C CA . ASP A 1 162 ? 54.482 96.217 61.325 1.00 13.98 ? 162 ASP M CA 1 ATOM 1285 C C . ASP A 1 162 ? 55.041 97.326 62.172 1.00 10.60 ? 162 ASP M C 1 ATOM 1286 O O . ASP A 1 162 ? 54.633 97.507 63.302 1.00 11.91 ? 162 ASP M O 1 ATOM 1287 C CB . ASP A 1 162 ? 55.267 94.972 61.504 1.00 16.57 ? 162 ASP M CB 1 ATOM 1288 C CG . ASP A 1 162 ? 54.452 93.673 61.145 1.00 24.79 ? 162 ASP M CG 1 ATOM 1289 O OD1 . ASP A 1 162 ? 53.175 93.680 61.020 1.00 32.07 ? 162 ASP M OD1 1 ATOM 1290 O OD2 . ASP A 1 162 ? 55.169 92.653 61.075 1.00 36.99 ? 162 ASP M OD2 1 ATOM 1291 N N . ASP A 1 163 ? 55.966 98.154 61.640 1.00 8.74 ? 163 ASP M N 1 ATOM 1292 C CA . ASP A 1 163 ? 56.517 99.266 62.399 1.00 10.19 ? 163 ASP M CA 1 ATOM 1293 C C . ASP A 1 163 ? 55.420 100.301 62.604 1.00 8.40 ? 163 ASP M C 1 ATOM 1294 O O . ASP A 1 163 ? 55.301 100.838 63.747 1.00 8.96 ? 163 ASP M O 1 ATOM 1295 C CB . ASP A 1 163 ? 57.723 99.858 61.691 1.00 10.58 ? 163 ASP M CB 1 ATOM 1296 C CG . ASP A 1 163 ? 58.996 99.062 61.912 1.00 13.25 ? 163 ASP M CG 1 ATOM 1297 O OD1 . ASP A 1 163 ? 59.035 98.216 62.866 1.00 16.51 ? 163 ASP M OD1 1 ATOM 1298 O OD2 . ASP A 1 163 ? 59.948 99.213 61.110 1.00 13.31 ? 163 ASP M OD2 1 ATOM 1299 N N . PHE A 1 164 ? 54.581 100.601 61.597 1.00 8.45 ? 164 PHE M N 1 ATOM 1300 C CA . PHE A 1 164 ? 53.485 101.495 61.784 1.00 7.96 ? 164 PHE M CA 1 ATOM 1301 C C . PHE A 1 164 ? 52.465 100.984 62.812 1.00 7.91 ? 164 PHE M C 1 ATOM 1302 O O . PHE A 1 164 ? 51.945 101.693 63.660 1.00 8.97 ? 164 PHE M O 1 ATOM 1303 C CB . PHE A 1 164 ? 52.827 101.841 60.436 1.00 9.02 ? 164 PHE M CB 1 ATOM 1304 C CG . PHE A 1 164 ? 51.741 102.888 60.507 1.00 9.14 ? 164 PHE M CG 1 ATOM 1305 C CD1 . PHE A 1 164 ? 51.972 104.125 61.029 1.00 10.47 ? 164 PHE M CD1 1 ATOM 1306 C CD2 . PHE A 1 164 ? 50.479 102.624 60.097 1.00 12.05 ? 164 PHE M CD2 1 ATOM 1307 C CE1 . PHE A 1 164 ? 50.986 105.073 61.081 1.00 12.00 ? 164 PHE M CE1 1 ATOM 1308 C CE2 . PHE A 1 164 ? 49.481 103.590 60.075 1.00 12.63 ? 164 PHE M CE2 1 ATOM 1309 C CZ . PHE A 1 164 ? 49.717 104.818 60.597 1.00 11.31 ? 164 PHE M CZ 1 ATOM 1310 N N . LYS A 1 165 ? 52.160 99.689 62.699 1.00 9.30 ? 165 LYS M N 1 ATOM 1311 C CA . LYS A 1 165 ? 51.264 99.058 63.649 1.00 9.34 ? 165 LYS M CA 1 ATOM 1312 C C . LYS A 1 165 ? 51.736 99.180 65.099 1.00 9.29 ? 165 LYS M C 1 ATOM 1313 O O . LYS A 1 165 ? 50.926 99.517 66.011 1.00 10.06 ? 165 LYS M O 1 ATOM 1314 C CB . LYS A 1 165 ? 51.055 97.563 63.251 1.00 10.81 ? 165 LYS M CB 1 ATOM 1315 C CG . LYS A 1 165 ? 50.054 96.847 64.175 1.00 14.92 ? 165 LYS M CG 1 ATOM 1316 C CD . LYS A 1 165 ? 50.053 95.310 63.947 1.00 24.35 ? 165 LYS M CD 1 ATOM 1317 C CE . LYS A 1 165 ? 49.247 94.607 65.086 1.00 32.22 ? 165 LYS M CE 1 ATOM 1318 N NZ . LYS A 1 165 ? 48.486 93.346 64.625 1.00 37.17 ? 165 LYS M NZ 1 ATOM 1319 N N . ASP A 1 166 ? 53.000 98.972 65.360 1.00 10.22 ? 166 ASP M N 1 ATOM 1320 C CA . ASP A 1 166 ? 53.522 99.009 66.718 1.00 9.94 ? 166 ASP M CA 1 ATOM 1321 C C . ASP A 1 166 ? 53.485 100.428 67.245 1.00 8.72 ? 166 ASP M C 1 ATOM 1322 O O . ASP A 1 166 ? 53.226 100.672 68.439 1.00 9.98 ? 166 ASP M O 1 ATOM 1323 C CB . ASP A 1 166 ? 54.913 98.446 66.756 1.00 10.87 ? 166 ASP M CB 1 ATOM 1324 C CG . ASP A 1 166 ? 54.965 96.947 66.522 1.00 17.45 ? 166 ASP M CG 1 ATOM 1325 O OD1 . ASP A 1 166 ? 53.945 96.302 66.888 1.00 18.96 ? 166 ASP M OD1 1 ATOM 1326 O OD2 . ASP A 1 166 ? 56.095 96.441 66.160 1.00 17.79 ? 166 ASP M OD2 1 ATOM 1327 N N . TYR A 1 167 ? 53.751 101.441 66.375 1.00 8.28 ? 167 TYR M N 1 ATOM 1328 C CA . TYR A 1 167 ? 53.634 102.855 66.745 1.00 8.00 ? 167 TYR M CA 1 ATOM 1329 C C . TYR A 1 167 ? 52.201 103.237 67.073 1.00 8.57 ? 167 TYR M C 1 ATOM 1330 O O . TYR A 1 167 ? 51.912 103.853 68.092 1.00 9.09 ? 167 TYR M O 1 ATOM 1331 C CB . TYR A 1 167 ? 54.200 103.706 65.590 1.00 8.07 ? 167 TYR M CB 1 ATOM 1332 C CG . TYR A 1 167 ? 53.754 105.113 65.546 1.00 7.38 ? 167 TYR M CG 1 ATOM 1333 C CD1 . TYR A 1 167 ? 54.121 105.947 66.590 1.00 10.48 ? 167 TYR M CD1 1 ATOM 1334 C CD2 . TYR A 1 167 ? 53.007 105.656 64.497 1.00 8.42 ? 167 TYR M CD2 1 ATOM 1335 C CE1 . TYR A 1 167 ? 53.678 107.227 66.579 1.00 7.06 ? 167 TYR M CE1 1 ATOM 1336 C CE2 . TYR A 1 167 ? 52.619 106.969 64.477 1.00 8.23 ? 167 TYR M CE2 1 ATOM 1337 C CZ . TYR A 1 167 ? 52.988 107.789 65.533 1.00 6.16 ? 167 TYR M CZ 1 ATOM 1338 O OH . TYR A 1 167 ? 52.605 109.108 65.527 1.00 9.43 ? 167 TYR M OH 1 ATOM 1339 N N . ALA A 1 168 ? 51.252 102.833 66.228 1.00 7.63 ? 168 ALA M N 1 ATOM 1340 C CA . ALA A 1 168 ? 49.878 103.112 66.466 1.00 7.69 ? 168 ALA M CA 1 ATOM 1341 C C . ALA A 1 168 ? 49.384 102.503 67.763 1.00 8.14 ? 168 ALA M C 1 ATOM 1342 O O . ALA A 1 168 ? 48.684 103.117 68.530 1.00 8.31 ? 168 ALA M O 1 ATOM 1343 C CB . ALA A 1 168 ? 48.976 102.614 65.299 1.00 9.80 ? 168 ALA M CB 1 ATOM 1344 N N . ASP A 1 169 ? 49.842 101.262 68.005 1.00 8.79 ? 169 ASP M N 1 ATOM 1345 C CA . ASP A 1 169 ? 49.513 100.509 69.242 1.00 9.75 ? 169 ASP M CA 1 ATOM 1346 C C . ASP A 1 169 ? 49.936 101.323 70.462 1.00 9.98 ? 169 ASP M C 1 ATOM 1347 O O . ASP A 1 169 ? 49.167 101.482 71.404 1.00 9.69 ? 169 ASP M O 1 ATOM 1348 C CB A ASP A 1 169 ? 50.126 99.128 69.299 0.70 8.87 ? 169 ASP M CB 1 ATOM 1349 C CB B ASP A 1 169 ? 50.236 99.152 69.152 0.30 10.59 ? 169 ASP M CB 1 ATOM 1350 C CG A ASP A 1 169 ? 49.715 98.386 70.529 0.70 12.02 ? 169 ASP M CG 1 ATOM 1351 C CG B ASP A 1 169 ? 49.819 98.153 70.202 0.30 13.05 ? 169 ASP M CG 1 ATOM 1352 O OD1 A ASP A 1 169 ? 48.546 98.021 70.587 0.70 10.21 ? 169 ASP M OD1 1 ATOM 1353 O OD1 B ASP A 1 169 ? 48.693 98.268 70.747 0.30 21.74 ? 169 ASP M OD1 1 ATOM 1354 O OD2 A ASP A 1 169 ? 50.512 98.286 71.532 0.70 14.49 ? 169 ASP M OD2 1 ATOM 1355 O OD2 B ASP A 1 169 ? 50.680 97.269 70.499 0.30 11.61 ? 169 ASP M OD2 1 ATOM 1356 N N . LEU A 1 170 ? 51.160 101.890 70.435 1.00 9.08 ? 170 LEU M N 1 ATOM 1357 C CA . LEU A 1 170 ? 51.610 102.750 71.501 1.00 9.14 ? 170 LEU M CA 1 ATOM 1358 C C . LEU A 1 170 ? 50.731 103.932 71.680 1.00 10.22 ? 170 LEU M C 1 ATOM 1359 O O . LEU A 1 170 ? 50.366 104.312 72.829 1.00 10.53 ? 170 LEU M O 1 ATOM 1360 C CB . LEU A 1 170 ? 53.041 103.161 71.229 1.00 9.40 ? 170 LEU M CB 1 ATOM 1361 C CG . LEU A 1 170 ? 53.658 104.174 72.226 1.00 11.09 ? 170 LEU M CG 1 ATOM 1362 C CD1 . LEU A 1 170 ? 53.808 103.491 73.592 1.00 13.51 ? 170 LEU M CD1 1 ATOM 1363 C CD2 . LEU A 1 170 ? 55.070 104.628 71.705 1.00 13.75 ? 170 LEU M CD2 1 ATOM 1364 N N . CYS A 1 171 ? 50.348 104.626 70.589 1.00 8.50 ? 171 CYS M N 1 ATOM 1365 C CA . CYS A 1 171 ? 49.509 105.816 70.638 1.00 8.81 ? 171 CYS M CA 1 ATOM 1366 C C . CYS A 1 171 ? 48.173 105.436 71.296 1.00 9.29 ? 171 CYS M C 1 ATOM 1367 O O . CYS A 1 171 ? 47.603 106.183 72.097 1.00 8.88 ? 171 CYS M O 1 ATOM 1368 C CB . CYS A 1 171 ? 49.246 106.388 69.309 1.00 7.18 ? 171 CYS M CB 1 ATOM 1369 S SG . CYS A 1 171 ? 50.759 107.129 68.612 1.00 10.65 ? 171 CYS M SG 1 ATOM 1370 N N . PHE A 1 172 ? 47.556 104.311 70.884 1.00 8.08 ? 172 PHE M N 1 ATOM 1371 C CA . PHE A 1 172 ? 46.250 103.951 71.452 1.00 8.69 ? 172 PHE M CA 1 ATOM 1372 C C . PHE A 1 172 ? 46.410 103.614 72.927 1.00 9.13 ? 172 PHE M C 1 ATOM 1373 O O . PHE A 1 172 ? 45.536 104.079 73.718 1.00 10.41 ? 172 PHE M O 1 ATOM 1374 C CB . PHE A 1 172 ? 45.679 102.759 70.705 1.00 9.61 ? 172 PHE M CB 1 ATOM 1375 C CG . PHE A 1 172 ? 45.453 102.928 69.184 1.00 8.66 ? 172 PHE M CG 1 ATOM 1376 C CD1 . PHE A 1 172 ? 45.109 104.123 68.612 1.00 8.64 ? 172 PHE M CD1 1 ATOM 1377 C CD2 . PHE A 1 172 ? 45.648 101.818 68.360 1.00 8.71 ? 172 PHE M CD2 1 ATOM 1378 C CE1 . PHE A 1 172 ? 44.900 104.258 67.283 1.00 9.87 ? 172 PHE M CE1 1 ATOM 1379 C CE2 . PHE A 1 172 ? 45.456 101.941 67.022 1.00 8.57 ? 172 PHE M CE2 1 ATOM 1380 C CZ . PHE A 1 172 ? 45.072 103.143 66.444 1.00 8.66 ? 172 PHE M CZ 1 ATOM 1381 N N . GLU A 1 173 ? 47.441 102.911 73.246 1.00 10.93 ? 173 GLU M N 1 ATOM 1382 C CA . GLU A 1 173 ? 47.685 102.575 74.684 1.00 10.73 ? 173 GLU M CA 1 ATOM 1383 C C . GLU A 1 173 ? 47.842 103.842 75.485 1.00 10.57 ? 173 GLU M C 1 ATOM 1384 O O . GLU A 1 173 ? 47.245 103.970 76.575 1.00 15.00 ? 173 GLU M O 1 ATOM 1385 C CB . GLU A 1 173 ? 48.935 101.783 74.790 1.00 14.47 ? 173 GLU M CB 1 ATOM 1386 C CG . GLU A 1 173 ? 49.440 101.379 76.140 1.00 20.34 ? 173 GLU M CG 1 ATOM 1387 C CD . GLU A 1 173 ? 50.844 100.758 75.987 1.00 27.08 ? 173 GLU M CD 1 ATOM 1388 O OE1 . GLU A 1 173 ? 50.911 99.632 75.441 1.00 31.21 ? 173 GLU M OE1 1 ATOM 1389 O OE2 . GLU A 1 173 ? 51.868 101.419 76.414 1.00 36.06 ? 173 GLU M OE2 1 ATOM 1390 N N . GLU A 1 174 ? 48.651 104.801 75.039 1.00 9.29 ? 174 GLU M N 1 ATOM 1391 C CA . GLU A 1 174 ? 48.952 105.942 75.890 1.00 10.23 ? 174 GLU M CA 1 ATOM 1392 C C . GLU A 1 174 ? 47.916 106.964 75.882 1.00 11.33 ? 174 GLU M C 1 ATOM 1393 O O . GLU A 1 174 ? 47.748 107.640 76.919 1.00 13.39 ? 174 GLU M O 1 ATOM 1394 C CB . GLU A 1 174 ? 50.319 106.596 75.388 1.00 10.99 ? 174 GLU M CB 1 ATOM 1395 C CG . GLU A 1 174 ? 51.498 105.729 75.590 1.00 14.57 ? 174 GLU M CG 1 ATOM 1396 C CD . GLU A 1 174 ? 51.881 105.559 77.073 1.00 23.69 ? 174 GLU M CD 1 ATOM 1397 O OE1 . GLU A 1 174 ? 51.556 106.430 77.867 1.00 22.86 ? 174 GLU M OE1 1 ATOM 1398 O OE2 . GLU A 1 174 ? 52.281 104.407 77.365 1.00 37.20 ? 174 GLU M OE2 1 ATOM 1399 N N . PHE A 1 175 ? 47.217 107.231 74.746 1.00 10.21 ? 175 PHE M N 1 ATOM 1400 C CA . PHE A 1 175 ? 46.341 108.336 74.611 1.00 9.28 ? 175 PHE M CA 1 ATOM 1401 C C . PHE A 1 175 ? 44.865 108.048 74.441 1.00 10.39 ? 175 PHE M C 1 ATOM 1402 O O . PHE A 1 175 ? 44.053 108.925 74.452 1.00 11.23 ? 175 PHE M O 1 ATOM 1403 C CB . PHE A 1 175 ? 46.837 109.294 73.446 1.00 10.04 ? 175 PHE M CB 1 ATOM 1404 C CG . PHE A 1 175 ? 48.331 109.564 73.518 1.00 10.14 ? 175 PHE M CG 1 ATOM 1405 C CD1 . PHE A 1 175 ? 48.892 110.317 74.581 1.00 10.29 ? 175 PHE M CD1 1 ATOM 1406 C CD2 . PHE A 1 175 ? 49.150 109.133 72.517 1.00 11.46 ? 175 PHE M CD2 1 ATOM 1407 C CE1 . PHE A 1 175 ? 50.236 110.486 74.596 1.00 10.54 ? 175 PHE M CE1 1 ATOM 1408 C CE2 . PHE A 1 175 ? 50.502 109.399 72.514 1.00 8.57 ? 175 PHE M CE2 1 ATOM 1409 C CZ . PHE A 1 175 ? 51.036 110.116 73.617 1.00 8.46 ? 175 PHE M CZ 1 ATOM 1410 N N . GLY A 1 176 ? 44.574 106.788 74.059 1.00 10.43 ? 176 GLY M N 1 ATOM 1411 C CA . GLY A 1 176 ? 43.222 106.416 73.645 1.00 10.48 ? 176 GLY M CA 1 ATOM 1412 C C . GLY A 1 176 ? 42.154 106.475 74.754 1.00 10.48 ? 176 GLY M C 1 ATOM 1413 O O . GLY A 1 176 ? 40.988 106.443 74.415 1.00 11.17 ? 176 GLY M O 1 ATOM 1414 N N . ASP A 1 177 ? 42.593 106.517 76.021 1.00 13.37 ? 177 ASP M N 1 ATOM 1415 C CA . ASP A 1 177 ? 41.568 106.788 77.010 1.00 15.40 ? 177 ASP M CA 1 ATOM 1416 C C . ASP A 1 177 ? 40.966 108.120 76.937 1.00 15.35 ? 177 ASP M C 1 ATOM 1417 O O . ASP A 1 177 ? 39.819 108.357 77.388 1.00 15.81 ? 177 ASP M O 1 ATOM 1418 C CB . ASP A 1 177 ? 42.107 106.482 78.388 1.00 18.49 ? 177 ASP M CB 1 ATOM 1419 C CG . ASP A 1 177 ? 42.342 104.966 78.544 1.00 30.86 ? 177 ASP M CG 1 ATOM 1420 O OD1 . ASP A 1 177 ? 41.597 104.070 77.943 1.00 39.92 ? 177 ASP M OD1 1 ATOM 1421 O OD2 . ASP A 1 177 ? 43.361 104.610 79.238 1.00 44.64 ? 177 ASP M OD2 1 ATOM 1422 N N . SER A 1 178 ? 41.602 109.112 76.286 1.00 13.38 ? 178 SER M N 1 ATOM 1423 C CA . SER A 1 178 ? 41.137 110.409 76.145 1.00 13.99 ? 178 SER M CA 1 ATOM 1424 C C . SER A 1 178 ? 40.816 110.849 74.726 1.00 13.61 ? 178 SER M C 1 ATOM 1425 O O . SER A 1 178 ? 39.888 111.554 74.449 1.00 17.83 ? 178 SER M O 1 ATOM 1426 C CB . SER A 1 178 ? 42.217 111.386 76.703 1.00 14.64 ? 178 SER M CB 1 ATOM 1427 O OG . SER A 1 178 ? 42.355 111.291 78.231 1.00 26.54 ? 178 SER M OG 1 ATOM 1428 N N . VAL A 1 179 ? 41.507 110.259 73.743 1.00 11.15 ? 179 VAL M N 1 ATOM 1429 C CA . VAL A 1 179 ? 41.283 110.602 72.327 1.00 9.03 ? 179 VAL M CA 1 ATOM 1430 C C . VAL A 1 179 ? 40.330 109.563 71.706 1.00 8.03 ? 179 VAL M C 1 ATOM 1431 O O . VAL A 1 179 ? 40.537 108.347 71.914 1.00 12.57 ? 179 VAL M O 1 ATOM 1432 C CB . VAL A 1 179 ? 42.608 110.425 71.565 1.00 9.45 ? 179 VAL M CB 1 ATOM 1433 C CG1 . VAL A 1 179 ? 42.439 110.555 70.025 1.00 10.91 ? 179 VAL M CG1 1 ATOM 1434 C CG2 . VAL A 1 179 ? 43.647 111.446 72.029 1.00 10.80 ? 179 VAL M CG2 1 ATOM 1435 N N . LYS A 1 180 ? 39.274 110.075 71.140 1.00 9.66 ? 180 LYS M N 1 ATOM 1436 C CA . LYS A 1 180 ? 38.196 109.250 70.564 1.00 11.87 ? 180 LYS M CA 1 ATOM 1437 C C . LYS A 1 180 ? 38.028 109.361 69.121 1.00 11.27 ? 180 LYS M C 1 ATOM 1438 O O . LYS A 1 180 ? 37.127 108.740 68.535 1.00 11.13 ? 180 LYS M O 1 ATOM 1439 C CB . LYS A 1 180 ? 36.845 109.566 71.285 1.00 13.06 ? 180 LYS M CB 1 ATOM 1440 C CG . LYS A 1 180 ? 36.987 109.468 72.851 1.00 13.71 ? 180 LYS M CG 1 ATOM 1441 C CD . LYS A 1 180 ? 37.439 108.168 73.354 1.00 17.00 ? 180 LYS M CD 1 ATOM 1442 C CE . LYS A 1 180 ? 37.576 108.068 74.971 1.00 21.03 ? 180 LYS M CE 1 ATOM 1443 N NZ . LYS A 1 180 ? 38.308 106.805 75.331 1.00 15.66 ? 180 LYS M NZ 1 ATOM 1444 N N . TYR A 1 181 ? 38.852 110.185 68.419 1.00 8.53 ? 181 TYR M N 1 ATOM 1445 C CA . TYR A 1 181 ? 38.797 110.345 67.009 1.00 8.73 ? 181 TYR M CA 1 ATOM 1446 C C . TYR A 1 181 ? 40.269 110.271 66.499 1.00 10.39 ? 181 TYR M C 1 ATOM 1447 O O . TYR A 1 181 ? 41.109 111.133 66.843 1.00 10.87 ? 181 TYR M O 1 ATOM 1448 C CB . TYR A 1 181 ? 38.212 111.678 66.557 1.00 9.11 ? 181 TYR M CB 1 ATOM 1449 C CG . TYR A 1 181 ? 36.726 111.794 66.827 1.00 10.39 ? 181 TYR M CG 1 ATOM 1450 C CD1 . TYR A 1 181 ? 36.309 112.337 68.017 1.00 12.99 ? 181 TYR M CD1 1 ATOM 1451 C CD2 . TYR A 1 181 ? 35.813 111.341 65.884 1.00 12.62 ? 181 TYR M CD2 1 ATOM 1452 C CE1 . TYR A 1 181 ? 34.934 112.477 68.288 1.00 14.54 ? 181 TYR M CE1 1 ATOM 1453 C CE2 . TYR A 1 181 ? 34.467 111.415 66.164 1.00 16.43 ? 181 TYR M CE2 1 ATOM 1454 C CZ . TYR A 1 181 ? 34.044 112.005 67.353 1.00 22.20 ? 181 TYR M CZ 1 ATOM 1455 O OH . TYR A 1 181 ? 32.633 112.109 67.657 1.00 26.49 ? 181 TYR M OH 1 ATOM 1456 N N . TRP A 1 182 ? 40.576 109.211 65.748 1.00 7.88 ? 182 TRP M N 1 ATOM 1457 C CA . TRP A 1 182 ? 41.923 108.959 65.244 1.00 7.19 ? 182 TRP M CA 1 ATOM 1458 C C . TRP A 1 182 ? 41.892 108.979 63.742 1.00 9.96 ? 182 TRP M C 1 ATOM 1459 O O . TRP A 1 182 ? 40.984 108.412 63.092 1.00 9.18 ? 182 TRP M O 1 ATOM 1460 C CB . TRP A 1 182 ? 42.389 107.588 65.645 1.00 9.26 ? 182 TRP M CB 1 ATOM 1461 C CG . TRP A 1 182 ? 42.667 107.451 67.112 1.00 8.38 ? 182 TRP M CG 1 ATOM 1462 C CD1 . TRP A 1 182 ? 41.868 106.841 68.048 1.00 9.18 ? 182 TRP M CD1 1 ATOM 1463 C CD2 . TRP A 1 182 ? 43.842 107.846 67.816 1.00 7.83 ? 182 TRP M CD2 1 ATOM 1464 N NE1 . TRP A 1 182 ? 42.414 106.904 69.286 1.00 9.89 ? 182 TRP M NE1 1 ATOM 1465 C CE2 . TRP A 1 182 ? 43.684 107.461 69.174 1.00 9.27 ? 182 TRP M CE2 1 ATOM 1466 C CE3 . TRP A 1 182 ? 45.009 108.454 67.413 1.00 8.58 ? 182 TRP M CE3 1 ATOM 1467 C CZ2 . TRP A 1 182 ? 44.670 107.704 70.131 1.00 9.10 ? 182 TRP M CZ2 1 ATOM 1468 C CZ3 . TRP A 1 182 ? 45.995 108.687 68.363 1.00 10.72 ? 182 TRP M CZ3 1 ATOM 1469 C CH2 . TRP A 1 182 ? 45.787 108.358 69.715 1.00 10.10 ? 182 TRP M CH2 1 ATOM 1470 N N . LEU A 1 183 ? 42.910 109.633 63.146 1.00 9.32 ? 183 LEU M N 1 ATOM 1471 C CA . LEU A 1 183 ? 43.157 109.596 61.737 1.00 9.39 ? 183 LEU M CA 1 ATOM 1472 C C . LEU A 1 183 ? 44.432 108.844 61.490 1.00 7.74 ? 183 LEU M C 1 ATOM 1473 O O . LEU A 1 183 ? 45.415 108.995 62.216 1.00 9.82 ? 183 LEU M O 1 ATOM 1474 C CB . LEU A 1 183 ? 43.296 110.976 61.146 1.00 9.66 ? 183 LEU M CB 1 ATOM 1475 C CG . LEU A 1 183 ? 42.066 111.863 61.143 1.00 15.71 ? 183 LEU M CG 1 ATOM 1476 C CD1 . LEU A 1 183 ? 40.858 111.238 60.460 1.00 14.81 ? 183 LEU M CD1 1 ATOM 1477 C CD2 . LEU A 1 183 ? 41.901 112.601 62.306 1.00 22.37 ? 183 LEU M CD2 1 ATOM 1478 N N . THR A 1 184 ? 44.461 107.928 60.529 1.00 8.24 ? 184 THR M N 1 ATOM 1479 C CA . THR A 1 184 ? 45.651 107.088 60.290 1.00 9.62 ? 184 THR M CA 1 ATOM 1480 C C . THR A 1 184 ? 46.726 107.792 59.515 1.00 11.31 ? 184 THR M C 1 ATOM 1481 O O . THR A 1 184 ? 47.746 108.196 60.064 1.00 12.07 ? 184 THR M O 1 ATOM 1482 C CB . THR A 1 184 ? 45.293 105.750 59.641 1.00 9.35 ? 184 THR M CB 1 ATOM 1483 O OG1 . THR A 1 184 ? 44.528 106.067 58.454 1.00 8.84 ? 184 THR M OG1 1 ATOM 1484 C CG2 . THR A 1 184 ? 44.424 104.936 60.618 1.00 11.55 ? 184 THR M CG2 1 ATOM 1485 N N . ILE A 1 185 ? 46.557 107.922 58.230 1.00 10.64 ? 185 ILE M N 1 ATOM 1486 C CA . ILE A 1 185 ? 47.524 108.550 57.305 1.00 9.42 ? 185 ILE M CA 1 ATOM 1487 C C . ILE A 1 185 ? 46.932 109.744 56.694 1.00 11.60 ? 185 ILE M C 1 ATOM 1488 O O . ILE A 1 185 ? 45.760 109.690 56.161 1.00 11.87 ? 185 ILE M O 1 ATOM 1489 C CB . ILE A 1 185 ? 47.968 107.520 56.259 1.00 10.97 ? 185 ILE M CB 1 ATOM 1490 C CG1 . ILE A 1 185 ? 48.627 106.292 56.900 1.00 11.74 ? 185 ILE M CG1 1 ATOM 1491 C CG2 . ILE A 1 185 ? 48.864 108.168 55.116 1.00 13.89 ? 185 ILE M CG2 1 ATOM 1492 C CD1 . ILE A 1 185 ? 49.048 105.183 55.935 1.00 13.25 ? 185 ILE M CD1 1 ATOM 1493 N N . ASN A 1 186 ? 47.593 110.891 56.746 1.00 9.39 ? 186 ASN M N 1 ATOM 1494 C CA . ASN A 1 186 ? 47.169 112.101 56.068 1.00 11.25 ? 186 ASN M CA 1 ATOM 1495 C C . ASN A 1 186 ? 47.238 112.080 54.567 1.00 12.84 ? 186 ASN M C 1 ATOM 1496 O O . ASN A 1 186 ? 48.295 111.832 54.013 1.00 15.09 ? 186 ASN M O 1 ATOM 1497 C CB . ASN A 1 186 ? 47.940 113.362 56.525 1.00 11.88 ? 186 ASN M CB 1 ATOM 1498 C CG . ASN A 1 186 ? 47.444 114.533 55.935 1.00 11.40 ? 186 ASN M CG 1 ATOM 1499 O OD1 . ASN A 1 186 ? 46.285 114.949 56.230 1.00 12.03 ? 186 ASN M OD1 1 ATOM 1500 N ND2 . ASN A 1 186 ? 48.251 115.239 55.148 1.00 12.60 ? 186 ASN M ND2 1 ATOM 1501 N N . GLN A 1 187 ? 46.101 112.356 53.893 1.00 9.88 ? 187 GLN M N 1 ATOM 1502 C CA . GLN A 1 187 ? 45.988 112.479 52.433 1.00 9.32 ? 187 GLN M CA 1 ATOM 1503 C C . GLN A 1 187 ? 46.675 111.333 51.717 1.00 10.18 ? 187 GLN M C 1 ATOM 1504 O O . GLN A 1 187 ? 47.793 111.493 51.169 1.00 10.26 ? 187 GLN M O 1 ATOM 1505 C CB . GLN A 1 187 ? 46.554 113.795 51.957 1.00 9.94 ? 187 GLN M CB 1 ATOM 1506 C CG . GLN A 1 187 ? 45.798 114.955 52.483 1.00 11.39 ? 187 GLN M CG 1 ATOM 1507 C CD . GLN A 1 187 ? 46.144 116.313 51.906 1.00 9.64 ? 187 GLN M CD 1 ATOM 1508 O OE1 . GLN A 1 187 ? 45.531 117.353 52.262 1.00 10.43 ? 187 GLN M OE1 1 ATOM 1509 N NE2 . GLN A 1 187 ? 47.083 116.394 50.900 1.00 10.23 ? 187 GLN M NE2 1 ATOM 1510 N N . LEU A 1 188 ? 45.998 110.216 51.597 1.00 9.23 ? 188 LEU M N 1 ATOM 1511 C CA . LEU A 1 188 ? 46.590 109.048 51.027 1.00 8.31 ? 188 LEU M CA 1 ATOM 1512 C C . LEU A 1 188 ? 47.238 109.285 49.649 1.00 7.88 ? 188 LEU M C 1 ATOM 1513 O O . LEU A 1 188 ? 48.276 108.637 49.320 1.00 8.04 ? 188 LEU M O 1 ATOM 1514 C CB . LEU A 1 188 ? 45.531 107.956 50.959 1.00 9.79 ? 188 LEU M CB 1 ATOM 1515 C CG . LEU A 1 188 ? 45.098 107.427 52.338 1.00 11.78 ? 188 LEU M CG 1 ATOM 1516 C CD1 . LEU A 1 188 ? 43.825 106.507 52.146 1.00 10.93 ? 188 LEU M CD1 1 ATOM 1517 C CD2 . LEU A 1 188 ? 46.228 106.581 52.816 1.00 15.72 ? 188 LEU M CD2 1 ATOM 1518 N N . TYR A 1 189 ? 46.632 110.076 48.822 1.00 9.01 ? 189 TYR M N 1 ATOM 1519 C CA . TYR A 1 189 ? 47.199 110.319 47.475 1.00 8.45 ? 189 TYR M CA 1 ATOM 1520 C C . TYR A 1 189 ? 48.576 111.007 47.434 1.00 8.71 ? 189 TYR M C 1 ATOM 1521 O O . TYR A 1 189 ? 49.318 110.837 46.474 1.00 8.42 ? 189 TYR M O 1 ATOM 1522 C CB . TYR A 1 189 ? 46.183 111.154 46.712 1.00 10.42 ? 189 TYR M CB 1 ATOM 1523 C CG . TYR A 1 189 ? 46.496 111.552 45.329 1.00 8.70 ? 189 TYR M CG 1 ATOM 1524 C CD1 . TYR A 1 189 ? 46.121 110.778 44.257 1.00 10.45 ? 189 TYR M CD1 1 ATOM 1525 C CD2 . TYR A 1 189 ? 47.170 112.768 45.068 1.00 9.21 ? 189 TYR M CD2 1 ATOM 1526 C CE1 . TYR A 1 189 ? 46.436 111.197 42.931 1.00 11.14 ? 189 TYR M CE1 1 ATOM 1527 C CE2 . TYR A 1 189 ? 47.501 113.134 43.778 1.00 11.52 ? 189 TYR M CE2 1 ATOM 1528 C CZ . TYR A 1 189 ? 47.143 112.334 42.737 1.00 11.96 ? 189 TYR M CZ 1 ATOM 1529 O OH . TYR A 1 189 ? 47.406 112.726 41.416 1.00 16.36 ? 189 TYR M OH 1 ATOM 1530 N N . SER A 1 190 ? 48.856 111.857 48.462 1.00 8.21 ? 190 SER M N 1 ATOM 1531 C CA . SER A 1 190 ? 49.967 112.751 48.403 1.00 7.31 ? 190 SER M CA 1 ATOM 1532 C C . SER A 1 190 ? 51.347 112.140 48.432 1.00 7.92 ? 190 SER M C 1 ATOM 1533 O O . SER A 1 190 ? 52.197 112.508 47.616 1.00 10.47 ? 190 SER M O 1 ATOM 1534 C CB . SER A 1 190 ? 49.814 113.831 49.528 1.00 8.91 ? 190 SER M CB 1 ATOM 1535 O OG . SER A 1 190 ? 48.587 114.535 49.342 1.00 9.69 ? 190 SER M OG 1 ATOM 1536 N N . VAL A 1 191 ? 51.669 111.323 49.393 1.00 7.33 ? 191 VAL M N 1 ATOM 1537 C CA . VAL A 1 191 ? 53.028 110.771 49.496 1.00 8.02 ? 191 VAL M CA 1 ATOM 1538 C C . VAL A 1 191 ? 53.350 109.970 48.315 1.00 8.79 ? 191 VAL M C 1 ATOM 1539 O O . VAL A 1 191 ? 54.401 110.159 47.720 1.00 8.39 ? 191 VAL M O 1 ATOM 1540 C CB . VAL A 1 191 ? 53.297 110.071 50.785 1.00 8.64 ? 191 VAL M CB 1 ATOM 1541 C CG1 . VAL A 1 191 ? 54.711 109.392 50.708 1.00 12.50 ? 191 VAL M CG1 1 ATOM 1542 C CG2 . VAL A 1 191 ? 53.171 110.999 52.034 1.00 9.82 ? 191 VAL M CG2 1 ATOM 1543 N N . PRO A 1 192 ? 52.440 109.099 47.813 1.00 7.10 ? 192 PRO M N 1 ATOM 1544 C CA . PRO A 1 192 ? 52.831 108.307 46.628 1.00 8.19 ? 192 PRO M CA 1 ATOM 1545 C C . PRO A 1 192 ? 53.180 109.192 45.470 1.00 8.27 ? 192 PRO M C 1 ATOM 1546 O O . PRO A 1 192 ? 54.133 108.896 44.711 1.00 9.01 ? 192 PRO M O 1 ATOM 1547 C CB . PRO A 1 192 ? 51.584 107.463 46.318 1.00 10.31 ? 192 PRO M CB 1 ATOM 1548 C CG . PRO A 1 192 ? 50.834 107.360 47.621 1.00 11.75 ? 192 PRO M CG 1 ATOM 1549 C CD . PRO A 1 192 ? 51.252 108.570 48.419 1.00 7.88 ? 192 PRO M CD 1 ATOM 1550 N N . THR A 1 193 ? 52.379 110.192 45.163 1.00 7.38 ? 193 THR M N 1 ATOM 1551 C CA . THR A 1 193 ? 52.550 111.001 43.999 1.00 7.43 ? 193 THR M CA 1 ATOM 1552 C C . THR A 1 193 ? 53.619 112.046 44.149 1.00 9.08 ? 193 THR M C 1 ATOM 1553 O O . THR A 1 193 ? 54.530 112.165 43.309 1.00 10.51 ? 193 THR M O 1 ATOM 1554 C CB . THR A 1 193 ? 51.257 111.626 43.570 1.00 9.48 ? 193 THR M CB 1 ATOM 1555 O OG1 . THR A 1 193 ? 50.713 112.447 44.549 1.00 10.10 ? 193 THR M OG1 1 ATOM 1556 C CG2 . THR A 1 193 ? 50.224 110.532 43.171 1.00 10.00 ? 193 THR M CG2 1 ATOM 1557 N N A ARG A 1 194 ? 53.563 112.834 45.214 0.50 8.12 ? 194 ARG M N 1 ATOM 1558 N N B ARG A 1 194 ? 53.547 112.839 45.217 0.50 8.24 ? 194 ARG M N 1 ATOM 1559 C CA A ARG A 1 194 ? 54.561 113.859 45.419 0.50 8.66 ? 194 ARG M CA 1 ATOM 1560 C CA B ARG A 1 194 ? 54.512 113.898 45.460 0.50 8.97 ? 194 ARG M CA 1 ATOM 1561 C C A ARG A 1 194 ? 55.874 113.369 45.982 0.50 8.09 ? 194 ARG M C 1 ATOM 1562 C C B ARG A 1 194 ? 55.846 113.421 46.019 0.50 8.09 ? 194 ARG M C 1 ATOM 1563 O O A ARG A 1 194 ? 56.931 113.912 45.644 0.50 10.07 ? 194 ARG M O 1 ATOM 1564 O O B ARG A 1 194 ? 56.880 114.062 45.720 0.50 9.70 ? 194 ARG M O 1 ATOM 1565 C CB A ARG A 1 194 ? 54.037 114.969 46.286 0.50 8.70 ? 194 ARG M CB 1 ATOM 1566 C CB B ARG A 1 194 ? 53.942 115.001 46.359 0.50 9.67 ? 194 ARG M CB 1 ATOM 1567 C CG A ARG A 1 194 ? 52.725 115.483 45.797 0.50 11.22 ? 194 ARG M CG 1 ATOM 1568 C CG B ARG A 1 194 ? 52.836 115.813 45.683 0.50 13.41 ? 194 ARG M CG 1 ATOM 1569 C CD A ARG A 1 194 ? 52.176 116.560 46.721 0.50 13.14 ? 194 ARG M CD 1 ATOM 1570 C CD B ARG A 1 194 ? 51.840 116.673 46.630 0.50 21.17 ? 194 ARG M CD 1 ATOM 1571 N NE A ARG A 1 194 ? 53.032 117.742 46.753 0.50 13.00 ? 194 ARG M NE 1 ATOM 1572 N NE B ARG A 1 194 ? 52.391 117.317 47.820 0.50 18.50 ? 194 ARG M NE 1 ATOM 1573 C CZ A ARG A 1 194 ? 53.055 118.732 45.880 0.50 18.48 ? 194 ARG M CZ 1 ATOM 1574 C CZ B ARG A 1 194 ? 51.911 118.363 48.507 0.50 22.09 ? 194 ARG M CZ 1 ATOM 1575 N NH1 A ARG A 1 194 ? 52.276 118.764 44.812 0.50 17.52 ? 194 ARG M NH1 1 ATOM 1576 N NH1 B ARG A 1 194 ? 50.726 118.973 48.147 0.50 23.00 ? 194 ARG M NH1 1 ATOM 1577 N NH2 A ARG A 1 194 ? 53.897 119.707 46.038 0.50 20.29 ? 194 ARG M NH2 1 ATOM 1578 N NH2 B ARG A 1 194 ? 52.628 118.778 49.612 0.50 11.04 ? 194 ARG M NH2 1 ATOM 1579 N N . GLY A 1 195 ? 55.827 112.342 46.830 1.00 7.99 ? 195 GLY M N 1 ATOM 1580 C CA . GLY A 1 195 ? 57.041 111.815 47.463 1.00 7.34 ? 195 GLY M CA 1 ATOM 1581 C C . GLY A 1 195 ? 57.804 110.837 46.640 1.00 8.64 ? 195 GLY M C 1 ATOM 1582 O O . GLY A 1 195 ? 58.986 110.754 46.790 1.00 9.54 ? 195 GLY M O 1 ATOM 1583 N N . TYR A 1 196 ? 57.114 110.085 45.770 1.00 7.45 ? 196 TYR M N 1 ATOM 1584 C CA . TYR A 1 196 ? 57.692 109.005 44.969 1.00 6.68 ? 196 TYR M CA 1 ATOM 1585 C C . TYR A 1 196 ? 57.452 109.152 43.468 1.00 9.55 ? 196 TYR M C 1 ATOM 1586 O O . TYR A 1 196 ? 57.866 108.323 42.692 1.00 9.36 ? 196 TYR M O 1 ATOM 1587 C CB . TYR A 1 196 ? 57.172 107.717 45.495 1.00 8.63 ? 196 TYR M CB 1 ATOM 1588 C CG . TYR A 1 196 ? 57.650 107.276 46.846 1.00 6.82 ? 196 TYR M CG 1 ATOM 1589 C CD1 . TYR A 1 196 ? 57.067 107.761 48.022 1.00 8.06 ? 196 TYR M CD1 1 ATOM 1590 C CD2 . TYR A 1 196 ? 58.685 106.402 46.992 1.00 8.67 ? 196 TYR M CD2 1 ATOM 1591 C CE1 . TYR A 1 196 ? 57.487 107.306 49.239 1.00 7.27 ? 196 TYR M CE1 1 ATOM 1592 C CE2 . TYR A 1 196 ? 59.098 105.928 48.219 1.00 9.43 ? 196 TYR M CE2 1 ATOM 1593 C CZ . TYR A 1 196 ? 58.510 106.373 49.332 1.00 8.70 ? 196 TYR M CZ 1 ATOM 1594 O OH . TYR A 1 196 ? 58.938 105.953 50.549 1.00 9.07 ? 196 TYR M OH 1 ATOM 1595 N N . GLY A 1 197 ? 56.722 110.211 43.105 1.00 8.12 ? 197 GLY M N 1 ATOM 1596 C CA . GLY A 1 197 ? 56.355 110.431 41.662 1.00 9.67 ? 197 GLY M CA 1 ATOM 1597 C C . GLY A 1 197 ? 57.074 111.646 41.122 1.00 10.28 ? 197 GLY M C 1 ATOM 1598 O O . GLY A 1 197 ? 57.999 111.523 40.288 1.00 12.72 ? 197 GLY M O 1 ATOM 1599 N N . SER A 1 198 ? 56.670 112.819 41.623 1.00 9.93 ? 198 SER M N 1 ATOM 1600 C CA . SER A 1 198 ? 57.319 114.089 41.203 1.00 9.12 ? 198 SER M CA 1 ATOM 1601 C C . SER A 1 198 ? 58.549 114.514 42.022 1.00 9.33 ? 198 SER M C 1 ATOM 1602 O O . SER A 1 198 ? 59.258 115.422 41.667 1.00 11.60 ? 198 SER M O 1 ATOM 1603 C CB . SER A 1 198 ? 56.284 115.154 41.226 1.00 12.85 ? 198 SER M CB 1 ATOM 1604 O OG . SER A 1 198 ? 55.751 115.314 42.528 1.00 12.73 ? 198 SER M OG 1 ATOM 1605 N N . ALA A 1 199 ? 58.637 113.886 43.197 1.00 10.45 ? 199 ALA M N 1 ATOM 1606 C CA . ALA A 1 199 ? 59.677 114.254 44.164 1.00 11.82 ? 199 ALA M CA 1 ATOM 1607 C C . ALA A 1 199 ? 59.592 115.644 44.631 1.00 9.02 ? 199 ALA M C 1 ATOM 1608 O O . ALA A 1 199 ? 60.615 116.296 45.042 1.00 12.37 ? 199 ALA M O 1 ATOM 1609 C CB . ALA A 1 199 ? 61.105 113.873 43.726 1.00 11.26 ? 199 ALA M CB 1 ATOM 1610 N N . LEU A 1 200 ? 58.413 116.281 44.650 1.00 9.22 ? 200 LEU M N 1 ATOM 1611 C CA . LEU A 1 200 ? 58.190 117.547 45.250 1.00 8.95 ? 200 LEU M CA 1 ATOM 1612 C C . LEU A 1 200 ? 58.188 117.465 46.776 1.00 10.22 ? 200 LEU M C 1 ATOM 1613 O O . LEU A 1 200 ? 58.491 118.505 47.442 1.00 10.10 ? 200 LEU M O 1 ATOM 1614 C CB . LEU A 1 200 ? 56.883 118.145 44.797 1.00 10.50 ? 200 LEU M CB 1 ATOM 1615 C CG . LEU A 1 200 ? 56.839 118.430 43.283 1.00 15.91 ? 200 LEU M CG 1 ATOM 1616 C CD1 . LEU A 1 200 ? 55.390 118.844 42.923 1.00 21.01 ? 200 LEU M CD1 1 ATOM 1617 C CD2 . LEU A 1 200 ? 57.877 119.438 42.899 1.00 22.12 ? 200 LEU M CD2 1 ATOM 1618 N N . ASP A 1 201 ? 57.937 116.293 47.357 1.00 9.91 ? 201 ASP M N 1 ATOM 1619 C CA . ASP A 1 201 ? 57.803 116.106 48.777 1.00 8.19 ? 201 ASP M CA 1 ATOM 1620 C C . ASP A 1 201 ? 58.817 115.015 49.217 1.00 7.49 ? 201 ASP M C 1 ATOM 1621 O O . ASP A 1 201 ? 59.250 114.140 48.431 1.00 8.68 ? 201 ASP M O 1 ATOM 1622 C CB . ASP A 1 201 ? 56.402 115.662 49.144 1.00 9.20 ? 201 ASP M CB 1 ATOM 1623 C CG . ASP A 1 201 ? 55.381 116.769 49.090 1.00 14.52 ? 201 ASP M CG 1 ATOM 1624 O OD1 . ASP A 1 201 ? 55.620 117.836 48.647 1.00 18.74 ? 201 ASP M OD1 1 ATOM 1625 O OD2 . ASP A 1 201 ? 54.219 116.470 49.509 1.00 14.62 ? 201 ASP M OD2 1 ATOM 1626 N N . ALA A 1 202 ? 59.027 114.900 50.529 1.00 7.97 ? 202 ALA M N 1 ATOM 1627 C CA . ALA A 1 202 ? 59.757 113.817 51.091 1.00 7.62 ? 202 ALA M CA 1 ATOM 1628 C C . ALA A 1 202 ? 59.106 112.484 50.790 1.00 6.93 ? 202 ALA M C 1 ATOM 1629 O O . ALA A 1 202 ? 57.888 112.413 50.778 1.00 7.90 ? 202 ALA M O 1 ATOM 1630 C CB . ALA A 1 202 ? 59.861 114.005 52.637 1.00 7.66 ? 202 ALA M CB 1 ATOM 1631 N N . PRO A 1 203 ? 59.883 111.432 50.550 1.00 7.15 ? 203 PRO M N 1 ATOM 1632 C CA . PRO A 1 203 ? 61.364 111.362 50.683 1.00 6.77 ? 203 PRO M CA 1 ATOM 1633 C C . PRO A 1 203 ? 62.125 111.867 49.453 1.00 8.56 ? 203 PRO M C 1 ATOM 1634 O O . PRO A 1 203 ? 63.352 112.053 49.551 1.00 11.24 ? 203 PRO M O 1 ATOM 1635 C CB . PRO A 1 203 ? 61.613 109.884 50.839 1.00 8.92 ? 203 PRO M CB 1 ATOM 1636 C CG . PRO A 1 203 ? 60.497 109.223 50.024 1.00 9.45 ? 203 PRO M CG 1 ATOM 1637 C CD . PRO A 1 203 ? 59.285 110.093 50.348 1.00 9.29 ? 203 PRO M CD 1 ATOM 1638 N N . GLY A 1 204 ? 61.447 112.269 48.362 1.00 7.96 ? 204 GLY M N 1 ATOM 1639 C CA . GLY A 1 204 ? 62.132 112.792 47.236 1.00 8.34 ? 204 GLY M CA 1 ATOM 1640 C C . GLY A 1 204 ? 62.660 111.787 46.269 1.00 9.43 ? 204 GLY M C 1 ATOM 1641 O O . GLY A 1 204 ? 63.744 112.010 45.759 1.00 11.05 ? 204 GLY M O 1 ATOM 1642 N N . ARG A 1 205 ? 61.941 110.771 45.970 1.00 9.88 ? 205 ARG M N 1 ATOM 1643 C CA . ARG A 1 205 ? 62.340 109.770 45.001 1.00 9.45 ? 205 ARG M CA 1 ATOM 1644 C C . ARG A 1 205 ? 61.555 109.947 43.710 1.00 9.98 ? 205 ARG M C 1 ATOM 1645 O O . ARG A 1 205 ? 60.401 110.390 43.711 1.00 10.22 ? 205 ARG M O 1 ATOM 1646 C CB . ARG A 1 205 ? 62.031 108.396 45.528 1.00 7.71 ? 205 ARG M CB 1 ATOM 1647 C CG . ARG A 1 205 ? 62.896 108.018 46.769 1.00 9.18 ? 205 ARG M CG 1 ATOM 1648 C CD . ARG A 1 205 ? 62.532 106.718 47.417 1.00 8.62 ? 205 ARG M CD 1 ATOM 1649 N NE . ARG A 1 205 ? 62.620 105.548 46.525 1.00 9.52 ? 205 ARG M NE 1 ATOM 1650 C CZ . ARG A 1 205 ? 63.664 104.722 46.413 1.00 10.21 ? 205 ARG M CZ 1 ATOM 1651 N NH1 . ARG A 1 205 ? 64.735 104.883 47.276 1.00 11.88 ? 205 ARG M NH1 1 ATOM 1652 N NH2 . ARG A 1 205 ? 63.783 103.793 45.510 1.00 10.54 ? 205 ARG M NH2 1 ATOM 1653 N N . CYS A 1 206 ? 62.265 109.609 42.596 1.00 9.83 ? 206 CYS M N 1 ATOM 1654 C CA . CYS A 1 206 ? 61.630 109.766 41.274 1.00 9.71 ? 206 CYS M CA 1 ATOM 1655 C C . CYS A 1 206 ? 62.557 109.128 40.241 1.00 10.31 ? 206 CYS M C 1 ATOM 1656 O O . CYS A 1 206 ? 63.626 108.685 40.566 1.00 10.54 ? 206 CYS M O 1 ATOM 1657 C CB . CYS A 1 206 ? 61.351 111.176 40.924 1.00 10.07 ? 206 CYS M CB 1 ATOM 1658 S SG . CYS A 1 206 ? 62.862 112.163 40.559 1.00 12.89 ? 206 CYS M SG 1 ATOM 1659 N N . SER A 1 207 ? 62.038 109.069 39.025 1.00 10.27 ? 207 SER M N 1 ATOM 1660 C CA . SER A 1 207 ? 62.885 108.561 37.953 1.00 10.46 ? 207 SER M CA 1 ATOM 1661 C C . SER A 1 207 ? 63.903 109.606 37.624 1.00 9.73 ? 207 SER M C 1 ATOM 1662 O O . SER A 1 207 ? 63.652 110.777 37.659 1.00 11.81 ? 207 SER M O 1 ATOM 1663 C CB . SER A 1 207 ? 61.968 108.373 36.717 1.00 10.33 ? 207 SER M CB 1 ATOM 1664 O OG . SER A 1 207 ? 61.014 107.348 36.864 1.00 10.71 ? 207 SER M OG 1 ATOM 1665 N N . PRO A 1 208 ? 65.125 109.165 37.186 1.00 12.05 ? 208 PRO M N 1 ATOM 1666 C CA . PRO A 1 208 ? 66.162 110.086 36.907 1.00 14.74 ? 208 PRO M CA 1 ATOM 1667 C C . PRO A 1 208 ? 65.884 111.201 35.955 1.00 15.74 ? 208 PRO M C 1 ATOM 1668 O O . PRO A 1 208 ? 66.376 112.273 36.134 1.00 17.20 ? 208 PRO M O 1 ATOM 1669 C CB . PRO A 1 208 ? 67.230 109.139 36.348 1.00 15.96 ? 208 PRO M CB 1 ATOM 1670 C CG . PRO A 1 208 ? 67.015 107.914 36.830 1.00 17.86 ? 208 PRO M CG 1 ATOM 1671 C CD . PRO A 1 208 ? 65.501 107.808 36.970 1.00 14.29 ? 208 PRO M CD 1 ATOM 1672 N N . THR A 1 209 ? 65.067 111.017 34.900 1.00 17.12 ? 209 THR M N 1 ATOM 1673 C CA . THR A 1 209 ? 64.807 112.133 34.010 1.00 18.57 ? 209 THR M CA 1 ATOM 1674 C C . THR A 1 209 ? 63.601 112.943 34.366 1.00 19.42 ? 209 THR M C 1 ATOM 1675 O O . THR A 1 209 ? 63.355 114.037 33.793 1.00 20.34 ? 209 THR M O 1 ATOM 1676 C CB . THR A 1 209 ? 64.628 111.597 32.510 1.00 19.01 ? 209 THR M CB 1 ATOM 1677 O OG1 . THR A 1 209 ? 63.469 110.779 32.394 1.00 20.55 ? 209 THR M OG1 1 ATOM 1678 C CG2 . THR A 1 209 ? 65.839 110.828 32.038 1.00 21.70 ? 209 THR M CG2 1 ATOM 1679 N N . VAL A 1 210 ? 62.845 112.521 35.377 1.00 15.53 ? 210 VAL M N 1 ATOM 1680 C CA . VAL A 1 210 ? 61.900 113.444 35.983 1.00 14.43 ? 210 VAL M CA 1 ATOM 1681 C C . VAL A 1 210 ? 62.510 114.565 36.770 1.00 15.05 ? 210 VAL M C 1 ATOM 1682 O O . VAL A 1 210 ? 62.173 115.713 36.696 1.00 18.02 ? 210 VAL M O 1 ATOM 1683 C CB . VAL A 1 210 ? 60.902 112.619 36.902 1.00 12.32 ? 210 VAL M CB 1 ATOM 1684 C CG1 . VAL A 1 210 ? 59.995 113.517 37.706 1.00 13.68 ? 210 VAL M CG1 1 ATOM 1685 C CG2 . VAL A 1 210 ? 60.018 111.618 36.037 1.00 13.73 ? 210 VAL M CG2 1 ATOM 1686 N N . ASP A 1 211 ? 63.490 114.201 37.594 1.00 14.10 ? 211 ASP M N 1 ATOM 1687 C CA . ASP A 1 211 ? 64.275 115.132 38.364 1.00 16.16 ? 211 ASP M CA 1 ATOM 1688 C C . ASP A 1 211 ? 65.591 114.521 38.686 1.00 14.40 ? 211 ASP M C 1 ATOM 1689 O O . ASP A 1 211 ? 65.734 113.624 39.461 1.00 14.89 ? 211 ASP M O 1 ATOM 1690 C CB . ASP A 1 211 ? 63.554 115.547 39.668 1.00 15.25 ? 211 ASP M CB 1 ATOM 1691 C CG . ASP A 1 211 ? 64.309 116.608 40.460 1.00 19.96 ? 211 ASP M CG 1 ATOM 1692 O OD1 . ASP A 1 211 ? 65.513 116.901 40.130 1.00 19.87 ? 211 ASP M OD1 1 ATOM 1693 O OD2 . ASP A 1 211 ? 63.724 117.125 41.444 1.00 20.47 ? 211 ASP M OD2 1 ATOM 1694 N N . PRO A 1 212 ? 66.682 115.006 38.028 1.00 15.19 ? 212 PRO M N 1 ATOM 1695 C CA . PRO A 1 212 ? 67.952 114.407 38.278 1.00 15.76 ? 212 PRO M CA 1 ATOM 1696 C C . PRO A 1 212 ? 68.542 114.560 39.637 1.00 14.66 ? 212 PRO M C 1 ATOM 1697 O O . PRO A 1 212 ? 69.428 113.794 39.971 1.00 16.54 ? 212 PRO M O 1 ATOM 1698 C CB . PRO A 1 212 ? 68.866 115.188 37.286 1.00 17.97 ? 212 PRO M CB 1 ATOM 1699 C CG . PRO A 1 212 ? 68.027 115.573 36.226 1.00 22.42 ? 212 PRO M CG 1 ATOM 1700 C CD . PRO A 1 212 ? 66.673 115.900 36.849 1.00 20.50 ? 212 PRO M CD 1 ATOM 1701 N N . SER A 1 213 ? 67.957 115.401 40.468 1.00 15.17 ? 213 SER M N 1 ATOM 1702 C CA . SER A 1 213 ? 68.389 115.527 41.867 1.00 17.51 ? 213 SER M CA 1 ATOM 1703 C C . SER A 1 213 ? 67.894 114.401 42.746 1.00 15.01 ? 213 SER M C 1 ATOM 1704 O O . SER A 1 213 ? 68.429 114.207 43.808 1.00 16.56 ? 213 SER M O 1 ATOM 1705 C CB A SER A 1 213 ? 68.003 116.877 42.425 0.70 18.68 ? 213 SER M CB 1 ATOM 1706 C CB B SER A 1 213 ? 67.865 116.817 42.470 0.30 17.12 ? 213 SER M CB 1 ATOM 1707 O OG A SER A 1 213 ? 66.617 117.048 42.551 0.70 24.38 ? 213 SER M OG 1 ATOM 1708 O OG B SER A 1 213 ? 68.382 117.929 41.779 0.30 17.98 ? 213 SER M OG 1 ATOM 1709 N N . CYS A 1 214 ? 66.875 113.675 42.366 1.00 13.20 ? 214 CYS M N 1 ATOM 1710 C CA . CYS A 1 214 ? 66.322 112.613 43.175 1.00 10.75 ? 214 CYS M CA 1 ATOM 1711 C C . CYS A 1 214 ? 67.483 111.570 43.466 1.00 13.06 ? 214 CYS M C 1 ATOM 1712 O O . CYS A 1 214 ? 68.303 111.214 42.541 1.00 13.02 ? 214 CYS M O 1 ATOM 1713 C CB . CYS A 1 214 ? 65.243 111.803 42.597 1.00 14.30 ? 214 CYS M CB 1 ATOM 1714 S SG . CYS A 1 214 ? 63.733 112.850 42.342 1.00 19.63 ? 214 CYS M SG 1 ATOM 1715 N N . TYR A 1 215 ? 67.613 111.061 44.672 1.00 12.08 ? 215 TYR M N 1 ATOM 1716 C CA . TYR A 1 215 ? 68.639 110.039 44.984 1.00 11.27 ? 215 TYR M CA 1 ATOM 1717 C C . TYR A 1 215 ? 68.424 108.655 44.419 1.00 11.71 ? 215 TYR M C 1 ATOM 1718 O O . TYR A 1 215 ? 69.392 107.876 44.270 1.00 12.15 ? 215 TYR M O 1 ATOM 1719 C CB . TYR A 1 215 ? 68.809 109.932 46.501 1.00 9.72 ? 215 TYR M CB 1 ATOM 1720 C CG . TYR A 1 215 ? 67.724 109.385 47.344 1.00 9.11 ? 215 TYR M CG 1 ATOM 1721 C CD1 . TYR A 1 215 ? 66.738 110.280 47.767 1.00 12.44 ? 215 TYR M CD1 1 ATOM 1722 C CD2 . TYR A 1 215 ? 67.661 108.069 47.740 1.00 11.11 ? 215 TYR M CD2 1 ATOM 1723 C CE1 . TYR A 1 215 ? 65.645 109.777 48.580 1.00 12.46 ? 215 TYR M CE1 1 ATOM 1724 C CE2 . TYR A 1 215 ? 66.618 107.630 48.575 1.00 11.84 ? 215 TYR M CE2 1 ATOM 1725 C CZ . TYR A 1 215 ? 65.657 108.518 48.994 1.00 13.46 ? 215 TYR M CZ 1 ATOM 1726 O OH . TYR A 1 215 ? 64.647 108.051 49.830 1.00 13.45 ? 215 TYR M OH 1 ATOM 1727 N N . ALA A 1 216 ? 67.162 108.320 44.106 1.00 9.87 ? 216 ALA M N 1 ATOM 1728 C CA . ALA A 1 216 ? 66.754 107.040 43.646 1.00 10.27 ? 216 ALA M CA 1 ATOM 1729 C C . ALA A 1 216 ? 65.310 107.154 43.258 1.00 9.04 ? 216 ALA M C 1 ATOM 1730 O O . ALA A 1 216 ? 64.664 108.169 43.572 1.00 9.44 ? 216 ALA M O 1 ATOM 1731 C CB . ALA A 1 216 ? 66.903 105.958 44.733 1.00 11.23 ? 216 ALA M CB 1 ATOM 1732 N N . GLY A 1 217 ? 64.775 106.131 42.611 1.00 10.13 ? 217 GLY M N 1 ATOM 1733 C CA . GLY A 1 217 ? 63.346 105.995 42.406 1.00 10.09 ? 217 GLY M CA 1 ATOM 1734 C C . GLY A 1 217 ? 62.924 105.604 41.012 1.00 10.94 ? 217 GLY M C 1 ATOM 1735 O O . GLY A 1 217 ? 63.750 105.313 40.104 1.00 12.31 ? 217 GLY M O 1 ATOM 1736 N N . ASN A 1 218 ? 61.589 105.523 40.847 1.00 10.15 ? 218 ASN M N 1 ATOM 1737 C CA . ASN A 1 218 ? 60.931 105.105 39.586 1.00 8.79 ? 218 ASN M CA 1 ATOM 1738 C C . ASN A 1 218 ? 59.524 105.665 39.713 1.00 8.28 ? 218 ASN M C 1 ATOM 1739 O O . ASN A 1 218 ? 58.684 105.119 40.452 1.00 9.03 ? 218 ASN M O 1 ATOM 1740 C CB . ASN A 1 218 ? 60.951 103.684 39.411 1.00 9.68 ? 218 ASN M CB 1 ATOM 1741 C CG . ASN A 1 218 ? 60.361 103.249 38.111 1.00 11.23 ? 218 ASN M CG 1 ATOM 1742 O OD1 . ASN A 1 218 ? 59.388 103.797 37.639 1.00 11.74 ? 218 ASN M OD1 1 ATOM 1743 N ND2 . ASN A 1 218 ? 61.008 102.243 37.510 1.00 12.44 ? 218 ASN M ND2 1 ATOM 1744 N N . SER A 1 219 ? 59.262 106.756 38.992 1.00 8.80 ? 219 SER M N 1 ATOM 1745 C CA . SER A 1 219 ? 57.970 107.499 39.139 1.00 7.77 ? 219 SER M CA 1 ATOM 1746 C C . SER A 1 219 ? 56.796 106.720 38.575 1.00 9.02 ? 219 SER M C 1 ATOM 1747 O O . SER A 1 219 ? 55.706 107.090 38.765 1.00 9.61 ? 219 SER M O 1 ATOM 1748 C CB . SER A 1 219 ? 58.107 108.810 38.400 1.00 9.37 ? 219 SER M CB 1 ATOM 1749 O OG . SER A 1 219 ? 59.133 109.668 38.954 1.00 9.47 ? 219 SER M OG 1 ATOM 1750 N N . SER A 1 220 ? 57.094 105.765 37.711 1.00 9.60 ? 220 SER M N 1 ATOM 1751 C CA . SER A 1 220 ? 56.053 104.931 37.090 1.00 10.38 ? 220 SER M CA 1 ATOM 1752 C C . SER A 1 220 ? 55.553 103.834 37.968 1.00 9.84 ? 220 SER M C 1 ATOM 1753 O O . SER A 1 220 ? 54.389 103.391 37.884 1.00 10.72 ? 220 SER M O 1 ATOM 1754 C CB A SER A 1 220 ? 56.681 104.431 35.776 0.70 10.60 ? 220 SER M CB 1 ATOM 1755 C CB B SER A 1 220 ? 56.640 104.200 35.899 0.30 10.20 ? 220 SER M CB 1 ATOM 1756 O OG A SER A 1 220 ? 55.666 103.827 35.015 0.70 13.22 ? 220 SER M OG 1 ATOM 1757 O OG B SER A 1 220 ? 56.777 105.091 34.855 0.30 7.39 ? 220 SER M OG 1 ATOM 1758 N N . THR A 1 221 ? 56.392 103.248 38.837 1.00 8.56 ? 221 THR M N 1 ATOM 1759 C CA . THR A 1 221 ? 56.060 102.119 39.632 1.00 9.41 ? 221 THR M CA 1 ATOM 1760 C C . THR A 1 221 ? 55.924 102.434 41.149 1.00 9.64 ? 221 THR M C 1 ATOM 1761 O O . THR A 1 221 ? 55.031 101.838 41.783 1.00 10.51 ? 221 THR M O 1 ATOM 1762 C CB . THR A 1 221 ? 57.159 101.025 39.511 1.00 11.47 ? 221 THR M CB 1 ATOM 1763 O OG1 . THR A 1 221 ? 58.442 101.607 39.826 1.00 11.84 ? 221 THR M OG1 1 ATOM 1764 C CG2 . THR A 1 221 ? 57.214 100.534 38.080 1.00 11.91 ? 221 THR M CG2 1 ATOM 1765 N N . GLU A 1 222 ? 56.813 103.256 41.659 1.00 9.11 ? 222 GLU M N 1 ATOM 1766 C CA . GLU A 1 222 ? 56.842 103.425 43.091 1.00 8.27 ? 222 GLU M CA 1 ATOM 1767 C C . GLU A 1 222 ? 55.586 104.078 43.677 1.00 9.02 ? 222 GLU M C 1 ATOM 1768 O O . GLU A 1 222 ? 55.150 103.646 44.786 1.00 8.97 ? 222 GLU M O 1 ATOM 1769 C CB . GLU A 1 222 ? 58.107 104.165 43.575 1.00 9.29 ? 222 GLU M CB 1 ATOM 1770 C CG . GLU A 1 222 ? 59.343 103.325 43.276 1.00 10.53 ? 222 GLU M CG 1 ATOM 1771 C CD . GLU A 1 222 ? 60.606 103.806 43.916 1.00 11.80 ? 222 GLU M CD 1 ATOM 1772 O OE1 . GLU A 1 222 ? 60.690 104.836 44.588 1.00 10.95 ? 222 GLU M OE1 1 ATOM 1773 O OE2 . GLU A 1 222 ? 61.655 102.997 43.815 1.00 10.90 ? 222 GLU M OE2 1 ATOM 1774 N N . PRO A 1 223 ? 54.931 105.000 42.972 1.00 6.95 ? 223 PRO M N 1 ATOM 1775 C CA . PRO A 1 223 ? 53.673 105.498 43.603 1.00 8.51 ? 223 PRO M CA 1 ATOM 1776 C C . PRO A 1 223 ? 52.676 104.431 43.890 1.00 8.31 ? 223 PRO M C 1 ATOM 1777 O O . PRO A 1 223 ? 51.989 104.438 44.908 1.00 8.10 ? 223 PRO M O 1 ATOM 1778 C CB . PRO A 1 223 ? 53.189 106.532 42.596 1.00 7.36 ? 223 PRO M CB 1 ATOM 1779 C CG . PRO A 1 223 ? 54.479 107.098 41.940 1.00 9.18 ? 223 PRO M CG 1 ATOM 1780 C CD . PRO A 1 223 ? 55.370 105.879 41.850 1.00 9.20 ? 223 PRO M CD 1 ATOM 1781 N N . TYR A 1 224 ? 52.585 103.420 43.003 1.00 7.61 ? 224 TYR M N 1 ATOM 1782 C CA . TYR A 1 224 ? 51.637 102.341 43.243 1.00 7.89 ? 224 TYR M CA 1 ATOM 1783 C C . TYR A 1 224 ? 52.037 101.423 44.353 1.00 7.67 ? 224 TYR M C 1 ATOM 1784 O O . TYR A 1 224 ? 51.216 101.011 45.116 1.00 8.64 ? 224 TYR M O 1 ATOM 1785 C CB . TYR A 1 224 ? 51.381 101.571 41.910 1.00 7.08 ? 224 TYR M CB 1 ATOM 1786 C CG . TYR A 1 224 ? 50.764 102.408 40.859 1.00 6.59 ? 224 TYR M CG 1 ATOM 1787 C CD1 . TYR A 1 224 ? 49.475 102.892 40.975 1.00 9.51 ? 224 TYR M CD1 1 ATOM 1788 C CD2 . TYR A 1 224 ? 51.513 102.780 39.774 1.00 8.13 ? 224 TYR M CD2 1 ATOM 1789 C CE1 . TYR A 1 224 ? 48.929 103.749 40.081 1.00 7.92 ? 224 TYR M CE1 1 ATOM 1790 C CE2 . TYR A 1 224 ? 50.975 103.671 38.817 1.00 7.60 ? 224 TYR M CE2 1 ATOM 1791 C CZ . TYR A 1 224 ? 49.657 104.100 38.956 1.00 8.37 ? 224 TYR M CZ 1 ATOM 1792 O OH . TYR A 1 224 ? 49.134 105.007 38.074 1.00 10.96 ? 224 TYR M OH 1 ATOM 1793 N N . ILE A 1 225 ? 53.324 101.162 44.512 1.00 8.05 ? 225 ILE M N 1 ATOM 1794 C CA . ILE A 1 225 ? 53.854 100.361 45.590 1.00 7.34 ? 225 ILE M CA 1 ATOM 1795 C C . ILE A 1 225 ? 53.558 101.034 46.916 1.00 7.96 ? 225 ILE M C 1 ATOM 1796 O O . ILE A 1 225 ? 53.099 100.383 47.847 1.00 8.41 ? 225 ILE M O 1 ATOM 1797 C CB . ILE A 1 225 ? 55.307 100.031 45.388 1.00 10.05 ? 225 ILE M CB 1 ATOM 1798 C CG1 . ILE A 1 225 ? 55.507 99.217 44.085 1.00 11.67 ? 225 ILE M CG1 1 ATOM 1799 C CG2 . ILE A 1 225 ? 55.862 99.256 46.623 1.00 11.32 ? 225 ILE M CG2 1 ATOM 1800 C CD1 . ILE A 1 225 ? 56.949 99.212 43.613 1.00 12.65 ? 225 ILE M CD1 1 ATOM 1801 N N . VAL A 1 226 ? 53.904 102.303 47.005 1.00 7.12 ? 226 VAL M N 1 ATOM 1802 C CA . VAL A 1 226 ? 53.756 103.090 48.245 1.00 6.89 ? 226 VAL M CA 1 ATOM 1803 C C . VAL A 1 226 ? 52.266 103.176 48.585 1.00 8.79 ? 226 VAL M C 1 ATOM 1804 O O . VAL A 1 226 ? 51.867 102.996 49.743 1.00 8.66 ? 226 VAL M O 1 ATOM 1805 C CB . VAL A 1 226 ? 54.393 104.398 48.118 1.00 7.88 ? 226 VAL M CB 1 ATOM 1806 C CG1 . VAL A 1 226 ? 54.001 105.411 49.251 1.00 9.69 ? 226 VAL M CG1 1 ATOM 1807 C CG2 . VAL A 1 226 ? 56.014 104.243 47.992 1.00 9.23 ? 226 VAL M CG2 1 ATOM 1808 N N . ALA A 1 227 ? 51.378 103.487 47.607 1.00 7.34 ? 227 ALA M N 1 ATOM 1809 C CA . ALA A 1 227 ? 49.964 103.597 47.850 1.00 6.77 ? 227 ALA M CA 1 ATOM 1810 C C . ALA A 1 227 ? 49.426 102.297 48.424 1.00 6.77 ? 227 ALA M C 1 ATOM 1811 O O . ALA A 1 227 ? 48.595 102.267 49.368 1.00 7.79 ? 227 ALA M O 1 ATOM 1812 C CB . ALA A 1 227 ? 49.259 103.946 46.575 1.00 8.21 ? 227 ALA M CB 1 ATOM 1813 N N . HIS A 1 228 ? 49.874 101.181 47.855 1.00 7.51 ? 228 HIS M N 1 ATOM 1814 C CA . HIS A 1 228 ? 49.423 99.867 48.338 1.00 8.21 ? 228 HIS M CA 1 ATOM 1815 C C . HIS A 1 228 ? 49.842 99.623 49.739 1.00 7.61 ? 228 HIS M C 1 ATOM 1816 O O . HIS A 1 228 ? 49.023 99.169 50.569 1.00 8.87 ? 228 HIS M O 1 ATOM 1817 C CB . HIS A 1 228 ? 50.050 98.791 47.404 1.00 8.50 ? 228 HIS M CB 1 ATOM 1818 C CG . HIS A 1 228 ? 49.398 97.495 47.433 1.00 9.11 ? 228 HIS M CG 1 ATOM 1819 N ND1 . HIS A 1 228 ? 48.121 97.292 46.917 1.00 11.38 ? 228 HIS M ND1 1 ATOM 1820 C CD2 . HIS A 1 228 ? 49.840 96.303 47.930 1.00 11.26 ? 228 HIS M CD2 1 ATOM 1821 C CE1 . HIS A 1 228 ? 47.855 95.988 47.071 1.00 12.56 ? 228 HIS M CE1 1 ATOM 1822 N NE2 . HIS A 1 228 ? 48.879 95.369 47.643 1.00 12.31 ? 228 HIS M NE2 1 ATOM 1823 N N . HIS A 1 229 ? 51.105 99.945 50.084 1.00 6.66 ? 229 HIS M N 1 ATOM 1824 C CA . HIS A 1 229 ? 51.557 99.754 51.443 1.00 8.99 ? 229 HIS M CA 1 ATOM 1825 C C . HIS A 1 229 ? 50.885 100.697 52.385 1.00 8.81 ? 229 HIS M C 1 ATOM 1826 O O . HIS A 1 229 ? 50.612 100.303 53.520 1.00 8.36 ? 229 HIS M O 1 ATOM 1827 C CB . HIS A 1 229 ? 53.078 99.869 51.550 1.00 8.34 ? 229 HIS M CB 1 ATOM 1828 C CG . HIS A 1 229 ? 53.797 98.805 50.813 1.00 9.28 ? 229 HIS M CG 1 ATOM 1829 N ND1 . HIS A 1 229 ? 55.093 99.004 50.352 1.00 10.51 ? 229 HIS M ND1 1 ATOM 1830 C CD2 . HIS A 1 229 ? 53.428 97.543 50.469 1.00 12.01 ? 229 HIS M CD2 1 ATOM 1831 C CE1 . HIS A 1 229 ? 55.470 97.904 49.713 1.00 11.34 ? 229 HIS M CE1 1 ATOM 1832 N NE2 . HIS A 1 229 ? 54.522 96.971 49.821 1.00 14.48 ? 229 HIS M NE2 1 ATOM 1833 N N . GLN A 1 230 ? 50.540 101.903 51.957 1.00 8.19 ? 230 GLN M N 1 ATOM 1834 C CA . GLN A 1 230 ? 49.790 102.787 52.822 1.00 7.13 ? 230 GLN M CA 1 ATOM 1835 C C . GLN A 1 230 ? 48.423 102.196 53.162 1.00 7.27 ? 230 GLN M C 1 ATOM 1836 O O . GLN A 1 230 ? 47.971 102.209 54.331 1.00 8.86 ? 230 GLN M O 1 ATOM 1837 C CB . GLN A 1 230 ? 49.530 104.094 52.145 1.00 6.64 ? 230 GLN M CB 1 ATOM 1838 C CG . GLN A 1 230 ? 50.714 105.000 52.079 1.00 8.20 ? 230 GLN M CG 1 ATOM 1839 C CD . GLN A 1 230 ? 50.370 106.403 51.527 1.00 12.34 ? 230 GLN M CD 1 ATOM 1840 O OE1 . GLN A 1 230 ? 51.056 107.342 51.850 1.00 14.07 ? 230 GLN M OE1 1 ATOM 1841 N NE2 . GLN A 1 230 ? 49.309 106.533 50.683 1.00 11.24 ? 230 GLN M NE2 1 ATOM 1842 N N . LEU A 1 231 ? 47.737 101.629 52.158 1.00 7.56 ? 231 LEU M N 1 ATOM 1843 C CA . LEU A 1 231 ? 46.444 100.970 52.419 1.00 8.05 ? 231 LEU M CA 1 ATOM 1844 C C . LEU A 1 231 ? 46.551 99.803 53.369 1.00 7.02 ? 231 LEU M C 1 ATOM 1845 O O . LEU A 1 231 ? 45.670 99.719 54.264 1.00 9.08 ? 231 LEU M O 1 ATOM 1846 C CB . LEU A 1 231 ? 45.770 100.583 51.084 1.00 7.52 ? 231 LEU M CB 1 ATOM 1847 C CG . LEU A 1 231 ? 45.196 101.730 50.288 1.00 7.01 ? 231 LEU M CG 1 ATOM 1848 C CD1 . LEU A 1 231 ? 45.025 101.292 48.778 1.00 8.68 ? 231 LEU M CD1 1 ATOM 1849 C CD2 . LEU A 1 231 ? 43.860 102.168 50.893 1.00 10.64 ? 231 LEU M CD2 1 ATOM 1850 N N . LEU A 1 232 ? 47.545 98.974 53.195 1.00 9.20 ? 232 LEU M N 1 ATOM 1851 C CA . LEU A 1 232 ? 47.727 97.814 54.062 1.00 9.26 ? 232 LEU M CA 1 ATOM 1852 C C . LEU A 1 232 ? 48.085 98.263 55.476 1.00 9.09 ? 232 LEU M C 1 ATOM 1853 O O . LEU A 1 232 ? 47.575 97.694 56.446 1.00 10.60 ? 232 LEU M O 1 ATOM 1854 C CB . LEU A 1 232 ? 48.746 96.879 53.527 1.00 10.96 ? 232 LEU M CB 1 ATOM 1855 C CG . LEU A 1 232 ? 48.425 96.206 52.192 1.00 12.33 ? 232 LEU M CG 1 ATOM 1856 C CD1 . LEU A 1 232 ? 49.683 95.477 51.686 1.00 16.67 ? 232 LEU M CD1 1 ATOM 1857 C CD2 . LEU A 1 232 ? 47.165 95.344 52.304 1.00 16.86 ? 232 LEU M CD2 1 ATOM 1858 N N . ALA A 1 233 ? 48.938 99.272 55.601 1.00 8.50 ? 233 ALA M N 1 ATOM 1859 C CA . ALA A 1 233 ? 49.391 99.771 56.911 1.00 8.07 ? 233 ALA M CA 1 ATOM 1860 C C . ALA A 1 233 ? 48.217 100.408 57.631 1.00 7.86 ? 233 ALA M C 1 ATOM 1861 O O . ALA A 1 233 ? 47.922 100.144 58.823 1.00 8.82 ? 233 ALA M O 1 ATOM 1862 C CB . ALA A 1 233 ? 50.546 100.748 56.784 1.00 9.45 ? 233 ALA M CB 1 ATOM 1863 N N . HIS A 1 234 ? 47.482 101.271 56.956 1.00 8.30 ? 234 HIS M N 1 ATOM 1864 C CA . HIS A 1 234 ? 46.216 101.807 57.434 1.00 7.87 ? 234 HIS M CA 1 ATOM 1865 C C . HIS A 1 234 ? 45.285 100.704 57.964 1.00 8.16 ? 234 HIS M C 1 ATOM 1866 O O . HIS A 1 234 ? 44.735 100.819 59.056 1.00 8.45 ? 234 HIS M O 1 ATOM 1867 C CB . HIS A 1 234 ? 45.537 102.645 56.343 1.00 9.36 ? 234 HIS M CB 1 ATOM 1868 C CG . HIS A 1 234 ? 44.082 102.801 56.505 1.00 7.53 ? 234 HIS M CG 1 ATOM 1869 N ND1 . HIS A 1 234 ? 43.561 103.744 57.343 1.00 7.18 ? 234 HIS M ND1 1 ATOM 1870 C CD2 . HIS A 1 234 ? 43.058 102.038 56.064 1.00 9.70 ? 234 HIS M CD2 1 ATOM 1871 C CE1 . HIS A 1 234 ? 42.252 103.572 57.404 1.00 10.23 ? 234 HIS M CE1 1 ATOM 1872 N NE2 . HIS A 1 234 ? 41.935 102.530 56.644 1.00 8.24 ? 234 HIS M NE2 1 ATOM 1873 N N . ALA A 1 235 ? 45.057 99.693 57.114 1.00 8.88 ? 235 ALA M N 1 ATOM 1874 C CA . ALA A 1 235 ? 44.054 98.660 57.482 1.00 9.62 ? 235 ALA M CA 1 ATOM 1875 C C . ALA A 1 235 ? 44.471 97.839 58.624 1.00 8.20 ? 235 ALA M C 1 ATOM 1876 O O . ALA A 1 235 ? 43.644 97.458 59.431 1.00 9.13 ? 235 ALA M O 1 ATOM 1877 C CB . ALA A 1 235 ? 43.740 97.850 56.246 1.00 8.11 ? 235 ALA M CB 1 ATOM 1878 N N . LYS A 1 236 ? 45.764 97.588 58.751 1.00 8.21 ? 236 LYS M N 1 ATOM 1879 C CA . LYS A 1 236 ? 46.297 96.767 59.872 1.00 8.94 ? 236 LYS M CA 1 ATOM 1880 C C . LYS A 1 236 ? 46.036 97.594 61.156 1.00 11.24 ? 236 LYS M C 1 ATOM 1881 O O . LYS A 1 236 ? 45.670 97.067 62.229 1.00 10.70 ? 236 LYS M O 1 ATOM 1882 C CB . LYS A 1 236 ? 47.750 96.565 59.706 1.00 11.58 ? 236 LYS M CB 1 ATOM 1883 C CG . LYS A 1 236 ? 48.398 95.613 60.676 1.00 20.86 ? 236 LYS M CG 1 ATOM 1884 C CD . LYS A 1 236 ? 48.110 94.210 60.071 1.00 33.47 ? 236 LYS M CD 1 ATOM 1885 C CE . LYS A 1 236 ? 48.874 93.085 60.771 1.00 40.37 ? 236 LYS M CE 1 ATOM 1886 N NZ . LYS A 1 236 ? 48.500 91.787 60.045 1.00 45.83 ? 236 LYS M NZ 1 ATOM 1887 N N . VAL A 1 237 ? 46.216 98.902 61.101 1.00 9.19 ? 237 VAL M N 1 ATOM 1888 C CA . VAL A 1 237 ? 46.059 99.737 62.295 1.00 8.03 ? 237 VAL M CA 1 ATOM 1889 C C . VAL A 1 237 ? 44.583 99.847 62.615 1.00 7.57 ? 237 VAL M C 1 ATOM 1890 O O . VAL A 1 237 ? 44.240 99.855 63.828 1.00 8.58 ? 237 VAL M O 1 ATOM 1891 C CB . VAL A 1 237 ? 46.673 101.128 62.058 1.00 9.52 ? 237 VAL M CB 1 ATOM 1892 C CG1 . VAL A 1 237 ? 46.191 102.192 63.030 1.00 11.04 ? 237 VAL M CG1 1 ATOM 1893 C CG2 . VAL A 1 237 ? 48.225 100.943 62.146 1.00 12.00 ? 237 VAL M CG2 1 ATOM 1894 N N . VAL A 1 238 ? 43.673 99.952 61.627 1.00 7.91 ? 238 VAL M N 1 ATOM 1895 C CA . VAL A 1 238 ? 42.267 100.042 61.890 1.00 7.90 ? 238 VAL M CA 1 ATOM 1896 C C . VAL A 1 238 ? 41.816 98.699 62.537 1.00 7.71 ? 238 VAL M C 1 ATOM 1897 O O . VAL A 1 238 ? 41.013 98.737 63.497 1.00 9.68 ? 238 VAL M O 1 ATOM 1898 C CB . VAL A 1 238 ? 41.471 100.322 60.701 1.00 8.86 ? 238 VAL M CB 1 ATOM 1899 C CG1 . VAL A 1 238 ? 39.933 100.195 60.913 1.00 9.42 ? 238 VAL M CG1 1 ATOM 1900 C CG2 . VAL A 1 238 ? 41.764 101.792 60.278 1.00 8.72 ? 238 VAL M CG2 1 ATOM 1901 N N . ASP A 1 239 ? 42.283 97.582 62.025 1.00 8.86 ? 239 ASP M N 1 ATOM 1902 C CA . ASP A 1 239 ? 41.945 96.270 62.659 1.00 9.82 ? 239 ASP M CA 1 ATOM 1903 C C . ASP A 1 239 ? 42.469 96.171 64.069 1.00 10.73 ? 239 ASP M C 1 ATOM 1904 O O . ASP A 1 239 ? 41.741 95.694 64.951 1.00 10.34 ? 239 ASP M O 1 ATOM 1905 C CB . ASP A 1 239 ? 42.526 95.175 61.760 1.00 10.20 ? 239 ASP M CB 1 ATOM 1906 C CG . ASP A 1 239 ? 42.373 93.754 62.292 1.00 18.45 ? 239 ASP M CG 1 ATOM 1907 O OD1 . ASP A 1 239 ? 41.308 93.253 62.079 1.00 17.83 ? 239 ASP M OD1 1 ATOM 1908 O OD2 . ASP A 1 239 ? 43.319 93.167 62.780 1.00 25.59 ? 239 ASP M OD2 1 ATOM 1909 N N . LEU A 1 240 ? 43.670 96.648 64.377 1.00 8.83 ? 240 LEU M N 1 ATOM 1910 C CA . LEU A 1 240 ? 44.196 96.616 65.732 1.00 9.04 ? 240 LEU M CA 1 ATOM 1911 C C . LEU A 1 240 ? 43.311 97.467 66.623 1.00 10.88 ? 240 LEU M C 1 ATOM 1912 O O . LEU A 1 240 ? 42.909 97.094 67.762 1.00 9.80 ? 240 LEU M O 1 ATOM 1913 C CB . LEU A 1 240 ? 45.593 97.239 65.739 1.00 10.45 ? 240 LEU M CB 1 ATOM 1914 C CG . LEU A 1 240 ? 46.191 97.579 67.126 1.00 12.96 ? 240 LEU M CG 1 ATOM 1915 C CD1 . LEU A 1 240 ? 46.403 96.238 67.867 1.00 18.12 ? 240 LEU M CD1 1 ATOM 1916 C CD2 . LEU A 1 240 ? 47.479 98.455 66.922 1.00 15.14 ? 240 LEU M CD2 1 ATOM 1917 N N . TYR A 1 241 ? 42.932 98.640 66.130 1.00 8.04 ? 241 TYR M N 1 ATOM 1918 C CA . TYR A 1 241 ? 42.125 99.557 66.915 1.00 7.19 ? 241 TYR M CA 1 ATOM 1919 C C . TYR A 1 241 ? 40.755 98.936 67.278 1.00 9.93 ? 241 TYR M C 1 ATOM 1920 O O . TYR A 1 241 ? 40.301 98.993 68.456 1.00 9.23 ? 241 TYR M O 1 ATOM 1921 C CB . TYR A 1 241 ? 41.915 100.929 66.232 1.00 6.89 ? 241 TYR M CB 1 ATOM 1922 C CG . TYR A 1 241 ? 41.226 101.888 67.089 1.00 6.92 ? 241 TYR M CG 1 ATOM 1923 C CD1 . TYR A 1 241 ? 41.879 102.486 68.136 1.00 8.34 ? 241 TYR M CD1 1 ATOM 1924 C CD2 . TYR A 1 241 ? 39.927 102.312 66.770 1.00 10.77 ? 241 TYR M CD2 1 ATOM 1925 C CE1 . TYR A 1 241 ? 41.211 103.344 68.955 1.00 8.71 ? 241 TYR M CE1 1 ATOM 1926 C CE2 . TYR A 1 241 ? 39.261 103.196 67.563 1.00 10.65 ? 241 TYR M CE2 1 ATOM 1927 C CZ . TYR A 1 241 ? 39.929 103.758 68.641 1.00 8.88 ? 241 TYR M CZ 1 ATOM 1928 O OH . TYR A 1 241 ? 39.225 104.692 69.425 1.00 11.11 ? 241 TYR M OH 1 ATOM 1929 N N . ARG A 1 242 ? 40.114 98.327 66.281 1.00 9.51 ? 242 ARG M N 1 ATOM 1930 C CA . ARG A 1 242 ? 38.741 97.868 66.397 1.00 10.09 ? 242 ARG M CA 1 ATOM 1931 C C . ARG A 1 242 ? 38.753 96.511 67.148 1.00 12.68 ? 242 ARG M C 1 ATOM 1932 O O . ARG A 1 242 ? 37.714 96.252 67.790 1.00 14.52 ? 242 ARG M O 1 ATOM 1933 C CB . ARG A 1 242 ? 37.996 97.824 65.072 1.00 10.43 ? 242 ARG M CB 1 ATOM 1934 C CG . ARG A 1 242 ? 37.911 99.286 64.555 1.00 10.75 ? 242 ARG M CG 1 ATOM 1935 C CD . ARG A 1 242 ? 36.826 99.571 63.513 1.00 15.30 ? 242 ARG M CD 1 ATOM 1936 N NE . ARG A 1 242 ? 37.049 98.907 62.316 1.00 12.83 ? 242 ARG M NE 1 ATOM 1937 C CZ . ARG A 1 242 ? 36.424 99.164 61.143 1.00 8.82 ? 242 ARG M CZ 1 ATOM 1938 N NH1 . ARG A 1 242 ? 35.502 100.052 60.990 1.00 13.26 ? 242 ARG M NH1 1 ATOM 1939 N NH2 . ARG A 1 242 ? 36.744 98.358 60.177 1.00 9.52 ? 242 ARG M NH2 1 ATOM 1940 N N . LYS A 1 243 ? 39.822 95.779 67.138 1.00 10.29 ? 243 LYS M N 1 ATOM 1941 C CA . LYS A 1 243 ? 39.912 94.479 67.843 1.00 10.14 ? 243 LYS M CA 1 ATOM 1942 C C . LYS A 1 243 ? 40.470 94.550 69.218 1.00 12.79 ? 243 LYS M C 1 ATOM 1943 O O . LYS A 1 243 ? 40.036 93.825 70.152 1.00 14.38 ? 243 LYS M O 1 ATOM 1944 C CB . LYS A 1 243 ? 40.597 93.457 67.043 1.00 13.09 ? 243 LYS M CB 1 ATOM 1945 C CG . LYS A 1 243 ? 39.818 93.123 65.791 1.00 17.47 ? 243 LYS M CG 1 ATOM 1946 C CD . LYS A 1 243 ? 40.324 91.993 65.173 1.00 21.53 ? 243 LYS M CD 1 ATOM 1947 C CE . LYS A 1 243 ? 39.318 91.565 64.066 1.00 22.15 ? 243 LYS M CE 1 ATOM 1948 N NZ . LYS A 1 243 ? 40.149 90.865 63.129 1.00 22.30 ? 243 LYS M NZ 1 ATOM 1949 N N . ASN A 1 244 ? 41.429 95.476 69.463 1.00 11.26 ? 244 ASN M N 1 ATOM 1950 C CA . ASN A 1 244 ? 42.107 95.536 70.743 1.00 12.12 ? 244 ASN M CA 1 ATOM 1951 C C . ASN A 1 244 ? 41.800 96.789 71.600 1.00 12.04 ? 244 ASN M C 1 ATOM 1952 O O . ASN A 1 244 ? 42.205 96.854 72.803 1.00 13.64 ? 244 ASN M O 1 ATOM 1953 C CB . ASN A 1 244 ? 43.619 95.444 70.521 1.00 10.50 ? 244 ASN M CB 1 ATOM 1954 C CG . ASN A 1 244 ? 44.064 94.073 70.229 1.00 20.90 ? 244 ASN M CG 1 ATOM 1955 O OD1 . ASN A 1 244 ? 43.281 93.197 70.067 1.00 26.66 ? 244 ASN M OD1 1 ATOM 1956 N ND2 . ASN A 1 244 ? 45.308 93.896 70.138 1.00 25.04 ? 244 ASN M ND2 1 ATOM 1957 N N . TYR A 1 245 ? 41.214 97.803 71.004 1.00 11.14 ? 245 TYR M N 1 ATOM 1958 C CA . TYR A 1 245 ? 40.892 99.076 71.664 1.00 9.78 ? 245 TYR M CA 1 ATOM 1959 C C . TYR A 1 245 ? 39.464 99.487 71.616 1.00 9.39 ? 245 TYR M C 1 ATOM 1960 O O . TYR A 1 245 ? 39.085 100.584 71.847 1.00 11.01 ? 245 TYR M O 1 ATOM 1961 C CB . TYR A 1 245 ? 41.866 100.180 71.160 1.00 10.76 ? 245 TYR M CB 1 ATOM 1962 C CG . TYR A 1 245 ? 43.254 99.906 71.534 1.00 9.38 ? 245 TYR M CG 1 ATOM 1963 C CD1 . TYR A 1 245 ? 43.717 100.280 72.793 1.00 12.52 ? 245 TYR M CD1 1 ATOM 1964 C CD2 . TYR A 1 245 ? 44.134 99.239 70.692 1.00 8.98 ? 245 TYR M CD2 1 ATOM 1965 C CE1 . TYR A 1 245 ? 44.979 99.962 73.166 1.00 9.26 ? 245 TYR M CE1 1 ATOM 1966 C CE2 . TYR A 1 245 ? 45.407 98.967 71.030 1.00 9.46 ? 245 TYR M CE2 1 ATOM 1967 C CZ . TYR A 1 245 ? 45.881 99.367 72.320 1.00 11.51 ? 245 TYR M CZ 1 ATOM 1968 O OH . TYR A 1 245 ? 47.165 98.999 72.704 1.00 14.28 ? 245 TYR M OH 1 ATOM 1969 N N . THR A 1 246 ? 38.517 98.488 71.418 1.00 11.05 ? 246 THR M N 1 ATOM 1970 C CA . THR A 1 246 ? 37.119 98.757 71.414 1.00 13.86 ? 246 THR M CA 1 ATOM 1971 C C . THR A 1 246 ? 36.556 99.329 72.705 1.00 11.32 ? 246 THR M C 1 ATOM 1972 O O . THR A 1 246 ? 35.643 100.145 72.673 1.00 13.87 ? 246 THR M O 1 ATOM 1973 C CB . THR A 1 246 ? 36.378 97.382 71.047 1.00 14.99 ? 246 THR M CB 1 ATOM 1974 O OG1 . THR A 1 246 ? 35.059 97.698 70.872 1.00 26.00 ? 246 THR M OG1 1 ATOM 1975 C CG2 . THR A 1 246 ? 36.433 96.469 72.048 1.00 19.59 ? 246 THR M CG2 1 ATOM 1976 N N . HIS A 1 247 ? 37.274 99.022 73.784 1.00 11.24 ? 247 HIS M N 1 ATOM 1977 C CA . HIS A 1 247 ? 36.892 99.497 75.073 1.00 12.83 ? 247 HIS M CA 1 ATOM 1978 C C . HIS A 1 247 ? 37.005 101.009 75.226 1.00 13.48 ? 247 HIS M C 1 ATOM 1979 O O . HIS A 1 247 ? 36.350 101.626 76.045 1.00 16.04 ? 247 HIS M O 1 ATOM 1980 C CB . HIS A 1 247 ? 37.695 98.804 76.157 1.00 14.91 ? 247 HIS M CB 1 ATOM 1981 C CG . HIS A 1 247 ? 39.202 99.033 76.097 1.00 14.70 ? 247 HIS M CG 1 ATOM 1982 N ND1 . HIS A 1 247 ? 40.033 98.350 75.240 1.00 14.30 ? 247 HIS M ND1 1 ATOM 1983 C CD2 . HIS A 1 247 ? 39.993 99.918 76.753 1.00 14.46 ? 247 HIS M CD2 1 ATOM 1984 C CE1 . HIS A 1 247 ? 41.274 98.750 75.461 1.00 18.38 ? 247 HIS M CE1 1 ATOM 1985 N NE2 . HIS A 1 247 ? 41.250 99.723 76.351 1.00 17.15 ? 247 HIS M NE2 1 ATOM 1986 N N . GLN A 1 248 ? 37.780 101.631 74.340 1.00 11.51 ? 248 GLN M N 1 ATOM 1987 C CA . GLN A 1 248 ? 37.910 103.088 74.406 1.00 10.77 ? 248 GLN M CA 1 ATOM 1988 C C . GLN A 1 248 ? 36.768 103.820 73.814 1.00 11.66 ? 248 GLN M C 1 ATOM 1989 O O . GLN A 1 248 ? 36.650 105.036 74.025 1.00 13.61 ? 248 GLN M O 1 ATOM 1990 C CB . GLN A 1 248 ? 39.323 103.449 73.707 1.00 9.35 ? 248 GLN M CB 1 ATOM 1991 C CG . GLN A 1 248 ? 40.496 102.916 74.450 1.00 11.65 ? 248 GLN M CG 1 ATOM 1992 C CD . GLN A 1 248 ? 41.851 103.257 73.902 1.00 11.46 ? 248 GLN M CD 1 ATOM 1993 O OE1 . GLN A 1 248 ? 41.902 103.673 72.749 1.00 11.17 ? 248 GLN M OE1 1 ATOM 1994 N NE2 . GLN A 1 248 ? 42.891 103.144 74.694 1.00 12.21 ? 248 GLN M NE2 1 ATOM 1995 N N . GLY A 1 249 ? 35.873 103.177 73.018 1.00 11.39 ? 249 GLY M N 1 ATOM 1996 C CA . GLY A 1 249 ? 34.714 103.877 72.555 1.00 14.34 ? 249 GLY M CA 1 ATOM 1997 C C . GLY A 1 249 ? 34.948 105.010 71.601 1.00 13.09 ? 249 GLY M C 1 ATOM 1998 O O . GLY A 1 249 ? 34.226 105.954 71.502 1.00 14.74 ? 249 GLY M O 1 ATOM 1999 N N . GLY A 1 250 ? 36.020 104.811 70.807 1.00 12.95 ? 250 GLY M N 1 ATOM 2000 C CA . GLY A 1 250 ? 36.333 105.798 69.792 1.00 9.44 ? 250 GLY M CA 1 ATOM 2001 C C . GLY A 1 250 ? 36.191 105.341 68.339 1.00 10.86 ? 250 GLY M C 1 ATOM 2002 O O . GLY A 1 250 ? 35.693 104.251 68.087 1.00 10.89 ? 250 GLY M O 1 ATOM 2003 N N . LYS A 1 251 ? 36.588 106.183 67.406 1.00 10.09 ? 251 LYS M N 1 ATOM 2004 C CA . LYS A 1 251 ? 36.454 105.932 66.004 1.00 8.03 ? 251 LYS M CA 1 ATOM 2005 C C . LYS A 1 251 ? 37.771 106.208 65.288 1.00 9.24 ? 251 LYS M C 1 ATOM 2006 O O . LYS A 1 251 ? 38.515 107.078 65.739 1.00 8.98 ? 251 LYS M O 1 ATOM 2007 C CB . LYS A 1 251 ? 35.374 106.787 65.446 1.00 10.09 ? 251 LYS M CB 1 ATOM 2008 C CG . LYS A 1 251 ? 33.924 106.465 65.913 1.00 15.74 ? 251 LYS M CG 1 ATOM 2009 C CD . LYS A 1 251 ? 32.959 107.338 65.196 1.00 19.34 ? 251 LYS M CD 1 ATOM 2010 C CE . LYS A 1 251 ? 31.508 107.247 65.790 1.00 32.26 ? 251 LYS M CE 1 ATOM 2011 N NZ . LYS A 1 251 ? 31.064 105.956 65.503 1.00 33.81 ? 251 LYS M NZ 1 ATOM 2012 N N . ILE A 1 252 ? 38.000 105.584 64.158 1.00 7.81 ? 252 ILE M N 1 ATOM 2013 C CA . ILE A 1 252 ? 39.216 105.764 63.397 1.00 7.20 ? 252 ILE M CA 1 ATOM 2014 C C . ILE A 1 252 ? 38.900 105.795 61.935 1.00 8.15 ? 252 ILE M C 1 ATOM 2015 O O . ILE A 1 252 ? 37.990 105.113 61.436 1.00 9.09 ? 252 ILE M O 1 ATOM 2016 C CB . ILE A 1 252 ? 40.227 104.647 63.749 1.00 8.14 ? 252 ILE M CB 1 ATOM 2017 C CG1 . ILE A 1 252 ? 41.613 104.846 63.138 1.00 8.67 ? 252 ILE M CG1 1 ATOM 2018 C CG2 . ILE A 1 252 ? 39.626 103.216 63.314 1.00 8.53 ? 252 ILE M CG2 1 ATOM 2019 C CD1 . ILE A 1 252 ? 42.727 104.102 63.887 1.00 8.86 ? 252 ILE M CD1 1 ATOM 2020 N N . GLY A 1 253 ? 39.694 106.560 61.160 1.00 7.22 ? 253 GLY M N 1 ATOM 2021 C CA . GLY A 1 253 ? 39.586 106.523 59.717 1.00 8.62 ? 253 GLY M CA 1 ATOM 2022 C C . GLY A 1 253 ? 40.798 107.103 59.033 1.00 9.05 ? 253 GLY M C 1 ATOM 2023 O O . GLY A 1 253 ? 41.681 107.686 59.708 1.00 8.26 ? 253 GLY M O 1 ATOM 2024 N N . PRO A 1 254 ? 40.847 107.025 57.708 1.00 7.24 ? 254 PRO M N 1 ATOM 2025 C CA . PRO A 1 254 ? 41.878 107.667 56.931 1.00 6.51 ? 254 PRO M CA 1 ATOM 2026 C C . PRO A 1 254 ? 41.550 109.064 56.625 1.00 9.60 ? 254 PRO M C 1 ATOM 2027 O O . PRO A 1 254 ? 40.455 109.480 56.811 1.00 8.99 ? 254 PRO M O 1 ATOM 2028 C CB . PRO A 1 254 ? 41.854 106.827 55.643 1.00 8.78 ? 254 PRO M CB 1 ATOM 2029 C CG . PRO A 1 254 ? 40.391 106.611 55.457 1.00 9.67 ? 254 PRO M CG 1 ATOM 2030 C CD . PRO A 1 254 ? 39.867 106.342 56.872 1.00 9.64 ? 254 PRO M CD 1 ATOM 2031 N N . THR A 1 255 ? 42.554 109.801 56.140 1.00 8.78 ? 255 THR M N 1 ATOM 2032 C CA . THR A 1 255 ? 42.340 111.139 55.548 1.00 9.10 ? 255 THR M CA 1 ATOM 2033 C C . THR A 1 255 ? 42.523 111.065 54.040 1.00 9.16 ? 255 THR M C 1 ATOM 2034 O O . THR A 1 255 ? 43.542 110.539 53.562 1.00 9.83 ? 255 THR M O 1 ATOM 2035 C CB . THR A 1 255 ? 43.250 112.161 56.108 1.00 7.72 ? 255 THR M CB 1 ATOM 2036 O OG1 . THR A 1 255 ? 43.022 112.331 57.585 1.00 18.86 ? 255 THR M OG1 1 ATOM 2037 C CG2 . THR A 1 255 ? 43.068 113.510 55.423 1.00 9.11 ? 255 THR M CG2 1 ATOM 2038 N N . MET A 1 256 ? 41.532 111.478 53.280 1.00 7.75 ? 256 MET M N 1 ATOM 2039 C CA . MET A 1 256 ? 41.656 111.636 51.891 1.00 8.20 ? 256 MET M CA 1 ATOM 2040 C C . MET A 1 256 ? 41.887 113.094 51.527 1.00 8.43 ? 256 MET M C 1 ATOM 2041 O O . MET A 1 256 ? 41.213 113.941 52.064 1.00 8.66 ? 256 MET M O 1 ATOM 2042 C CB . MET A 1 256 ? 40.413 111.252 51.140 1.00 9.86 ? 256 MET M CB 1 ATOM 2043 C CG . MET A 1 256 ? 40.084 109.811 51.159 1.00 11.76 ? 256 MET M CG 1 ATOM 2044 S SD . MET A 1 256 ? 41.114 108.825 50.044 1.00 13.24 ? 256 MET M SD 1 ATOM 2045 C CE . MET A 1 256 ? 40.439 109.462 48.458 1.00 13.72 ? 256 MET M CE 1 ATOM 2046 N N . ILE A 1 257 ? 42.749 113.416 50.542 1.00 7.29 ? 257 ILE M N 1 ATOM 2047 C CA . ILE A 1 257 ? 42.650 114.659 49.789 1.00 8.25 ? 257 ILE M CA 1 ATOM 2048 C C . ILE A 1 257 ? 41.538 114.466 48.771 1.00 9.25 ? 257 ILE M C 1 ATOM 2049 O O . ILE A 1 257 ? 41.522 113.451 48.012 1.00 9.74 ? 257 ILE M O 1 ATOM 2050 C CB . ILE A 1 257 ? 43.971 115.160 49.257 1.00 7.55 ? 257 ILE M CB 1 ATOM 2051 C CG1 . ILE A 1 257 ? 43.798 116.454 48.481 1.00 6.83 ? 257 ILE M CG1 1 ATOM 2052 C CG2 . ILE A 1 257 ? 44.709 114.121 48.372 1.00 9.17 ? 257 ILE M CG2 1 ATOM 2053 C CD1 . ILE A 1 257 ? 43.362 117.631 49.374 1.00 9.55 ? 257 ILE M CD1 1 ATOM 2054 N N . THR A 1 258 ? 40.613 115.392 48.772 1.00 8.54 ? 258 THR M N 1 ATOM 2055 C CA . THR A 1 258 ? 39.565 115.390 47.751 1.00 7.30 ? 258 THR M CA 1 ATOM 2056 C C . THR A 1 258 ? 39.680 116.643 46.883 1.00 8.89 ? 258 THR M C 1 ATOM 2057 O O . THR A 1 258 ? 40.110 117.682 47.344 1.00 8.85 ? 258 THR M O 1 ATOM 2058 C CB . THR A 1 258 ? 38.184 115.316 48.354 1.00 9.24 ? 258 THR M CB 1 ATOM 2059 O OG1 . THR A 1 258 ? 37.799 116.527 49.045 1.00 9.42 ? 258 THR M OG1 1 ATOM 2060 C CG2 . THR A 1 258 ? 38.004 114.093 49.317 1.00 9.25 ? 258 THR M CG2 1 ATOM 2061 N N . ARG A 1 259 ? 39.300 116.493 45.635 1.00 9.06 ? 259 ARG M N 1 ATOM 2062 C CA . ARG A 1 259 ? 39.047 117.554 44.658 1.00 8.26 ? 259 ARG M CA 1 ATOM 2063 C C . ARG A 1 259 ? 37.749 117.170 44.000 1.00 7.84 ? 259 ARG M C 1 ATOM 2064 O O . ARG A 1 259 ? 37.450 115.975 43.961 1.00 8.92 ? 259 ARG M O 1 ATOM 2065 C CB . ARG A 1 259 ? 40.154 117.646 43.611 1.00 9.09 ? 259 ARG M CB 1 ATOM 2066 C CG . ARG A 1 259 ? 41.550 117.984 44.146 1.00 9.21 ? 259 ARG M CG 1 ATOM 2067 C CD . ARG A 1 259 ? 42.576 117.978 43.031 1.00 11.17 ? 259 ARG M CD 1 ATOM 2068 N NE . ARG A 1 259 ? 43.896 118.072 43.597 1.00 11.22 ? 259 ARG M NE 1 ATOM 2069 C CZ . ARG A 1 259 ? 44.983 117.767 42.914 1.00 13.60 ? 259 ARG M CZ 1 ATOM 2070 N NH1 . ARG A 1 259 ? 44.928 117.541 41.643 1.00 14.60 ? 259 ARG M NH1 1 ATOM 2071 N NH2 . ARG A 1 259 ? 46.165 117.721 43.552 1.00 16.33 ? 259 ARG M NH2 1 ATOM 2072 N N . TRP A 1 260 ? 37.108 118.163 43.390 1.00 9.01 ? 260 TRP M N 1 ATOM 2073 C CA . TRP A 1 260 ? 36.111 117.827 42.429 1.00 8.28 ? 260 TRP M CA 1 ATOM 2074 C C . TRP A 1 260 ? 36.783 117.978 41.029 1.00 7.22 ? 260 TRP M C 1 ATOM 2075 O O . TRP A 1 260 ? 37.834 118.617 40.881 1.00 7.65 ? 260 TRP M O 1 ATOM 2076 C CB . TRP A 1 260 ? 34.842 118.600 42.573 1.00 9.80 ? 260 TRP M CB 1 ATOM 2077 C CG . TRP A 1 260 ? 33.634 118.065 41.777 1.00 7.79 ? 260 TRP M CG 1 ATOM 2078 C CD1 . TRP A 1 260 ? 32.867 118.748 40.905 1.00 9.63 ? 260 TRP M CD1 1 ATOM 2079 C CD2 . TRP A 1 260 ? 33.159 116.747 41.812 1.00 8.88 ? 260 TRP M CD2 1 ATOM 2080 N NE1 . TRP A 1 260 ? 31.879 117.896 40.383 1.00 10.14 ? 260 TRP M NE1 1 ATOM 2081 C CE2 . TRP A 1 260 ? 32.089 116.672 40.922 1.00 10.50 ? 260 TRP M CE2 1 ATOM 2082 C CE3 . TRP A 1 260 ? 33.544 115.596 42.501 1.00 10.78 ? 260 TRP M CE3 1 ATOM 2083 C CZ2 . TRP A 1 260 ? 31.365 115.502 40.750 1.00 10.62 ? 260 TRP M CZ2 1 ATOM 2084 C CZ3 . TRP A 1 260 ? 32.824 114.415 42.361 1.00 11.39 ? 260 TRP M CZ3 1 ATOM 2085 C CH2 . TRP A 1 260 ? 31.697 114.415 41.497 1.00 10.93 ? 260 TRP M CH2 1 ATOM 2086 N N . PHE A 1 261 ? 36.176 117.399 39.990 1.00 6.02 ? 261 PHE M N 1 ATOM 2087 C CA . PHE A 1 261 ? 36.601 117.493 38.622 1.00 8.02 ? 261 PHE M CA 1 ATOM 2088 C C . PHE A 1 261 ? 35.415 117.802 37.781 1.00 9.86 ? 261 PHE M C 1 ATOM 2089 O O . PHE A 1 261 ? 34.358 117.192 37.944 1.00 9.76 ? 261 PHE M O 1 ATOM 2090 C CB . PHE A 1 261 ? 37.301 116.256 38.140 1.00 8.45 ? 261 PHE M CB 1 ATOM 2091 C CG . PHE A 1 261 ? 38.496 115.903 39.004 1.00 7.83 ? 261 PHE M CG 1 ATOM 2092 C CD1 . PHE A 1 261 ? 39.665 116.567 38.808 1.00 9.54 ? 261 PHE M CD1 1 ATOM 2093 C CD2 . PHE A 1 261 ? 38.452 114.969 39.991 1.00 7.93 ? 261 PHE M CD2 1 ATOM 2094 C CE1 . PHE A 1 261 ? 40.745 116.332 39.625 1.00 11.35 ? 261 PHE M CE1 1 ATOM 2095 C CE2 . PHE A 1 261 ? 39.536 114.719 40.797 1.00 10.88 ? 261 PHE M CE2 1 ATOM 2096 C CZ . PHE A 1 261 ? 40.687 115.302 40.601 1.00 9.53 ? 261 PHE M CZ 1 ATOM 2097 N N . LEU A 1 262 ? 35.583 118.718 36.884 1.00 8.07 ? 262 LEU M N 1 ATOM 2098 C CA . LEU A 1 262 ? 34.582 119.096 35.880 1.00 9.18 ? 262 LEU M CA 1 ATOM 2099 C C . LEU A 1 262 ? 35.237 118.969 34.485 1.00 8.97 ? 262 LEU M C 1 ATOM 2100 O O . LEU A 1 262 ? 36.425 119.134 34.288 1.00 7.95 ? 262 LEU M O 1 ATOM 2101 C CB . LEU A 1 262 ? 34.144 120.540 36.067 1.00 9.54 ? 262 LEU M CB 1 ATOM 2102 C CG . LEU A 1 262 ? 33.467 120.929 37.296 1.00 10.49 ? 262 LEU M CG 1 ATOM 2103 C CD1 . LEU A 1 262 ? 33.259 122.430 37.463 1.00 13.48 ? 262 LEU M CD1 1 ATOM 2104 C CD2 . LEU A 1 262 ? 32.121 120.127 37.424 1.00 13.80 ? 262 LEU M CD2 1 ATOM 2105 N N . PRO A 1 263 ? 34.440 118.704 33.421 1.00 8.00 ? 263 PRO M N 1 ATOM 2106 C CA . PRO A 1 263 ? 35.030 118.641 32.092 1.00 7.15 ? 263 PRO M CA 1 ATOM 2107 C C . PRO A 1 263 ? 35.516 120.043 31.644 1.00 8.19 ? 263 PRO M C 1 ATOM 2108 O O . PRO A 1 263 ? 34.772 121.016 31.750 1.00 9.32 ? 263 PRO M O 1 ATOM 2109 C CB . PRO A 1 263 ? 33.870 118.183 31.205 1.00 9.50 ? 263 PRO M CB 1 ATOM 2110 C CG . PRO A 1 263 ? 32.775 118.027 32.082 1.00 15.07 ? 263 PRO M CG 1 ATOM 2111 C CD . PRO A 1 263 ? 32.996 118.484 33.481 1.00 11.51 ? 263 PRO M CD 1 ATOM 2112 N N . TYR A 1 264 ? 36.726 120.027 31.101 1.00 8.90 ? 264 TYR M N 1 ATOM 2113 C CA . TYR A 1 264 ? 37.281 121.163 30.384 1.00 8.39 ? 264 TYR M CA 1 ATOM 2114 C C . TYR A 1 264 ? 36.359 121.671 29.298 1.00 11.39 ? 264 TYR M C 1 ATOM 2115 O O . TYR A 1 264 ? 36.181 122.834 29.026 1.00 9.69 ? 264 TYR M O 1 ATOM 2116 C CB . TYR A 1 264 ? 38.585 120.809 29.837 1.00 8.63 ? 264 TYR M CB 1 ATOM 2117 C CG . TYR A 1 264 ? 39.312 121.835 28.963 1.00 9.88 ? 264 TYR M CG 1 ATOM 2118 C CD1 . TYR A 1 264 ? 39.937 122.945 29.551 1.00 11.02 ? 264 TYR M CD1 1 ATOM 2119 C CD2 . TYR A 1 264 ? 39.386 121.655 27.619 1.00 10.69 ? 264 TYR M CD2 1 ATOM 2120 C CE1 . TYR A 1 264 ? 40.594 123.834 28.752 1.00 13.69 ? 264 TYR M CE1 1 ATOM 2121 C CE2 . TYR A 1 264 ? 40.115 122.626 26.817 1.00 10.32 ? 264 TYR M CE2 1 ATOM 2122 C CZ . TYR A 1 264 ? 40.675 123.635 27.471 1.00 14.32 ? 264 TYR M CZ 1 ATOM 2123 O OH . TYR A 1 264 ? 41.370 124.619 26.697 1.00 15.08 ? 264 TYR M OH 1 ATOM 2124 N N . ASN A 1 265 ? 35.679 120.728 28.606 1.00 9.51 ? 265 ASN M N 1 ATOM 2125 C CA . ASN A 1 265 ? 34.659 121.074 27.578 1.00 10.29 ? 265 ASN M CA 1 ATOM 2126 C C . ASN A 1 265 ? 33.445 120.157 27.898 1.00 9.56 ? 265 ASN M C 1 ATOM 2127 O O . ASN A 1 265 ? 33.605 118.900 27.667 1.00 9.73 ? 265 ASN M O 1 ATOM 2128 C CB . ASN A 1 265 ? 35.194 120.862 26.189 1.00 11.10 ? 265 ASN M CB 1 ATOM 2129 C CG . ASN A 1 265 ? 34.177 121.214 25.140 1.00 10.06 ? 265 ASN M CG 1 ATOM 2130 O OD1 . ASN A 1 265 ? 32.995 121.121 25.394 1.00 13.10 ? 265 ASN M OD1 1 ATOM 2131 N ND2 . ASN A 1 265 ? 34.696 121.577 23.974 1.00 11.58 ? 265 ASN M ND2 1 ATOM 2132 N N . ASP A 1 266 ? 32.358 120.696 28.398 1.00 11.74 ? 266 ASP M N 1 ATOM 2133 C CA . ASP A 1 266 ? 31.264 119.887 28.863 1.00 12.86 ? 266 ASP M CA 1 ATOM 2134 C C . ASP A 1 266 ? 30.362 119.313 27.786 1.00 12.37 ? 266 ASP M C 1 ATOM 2135 O O . ASP A 1 266 ? 29.421 118.616 28.168 1.00 14.36 ? 266 ASP M O 1 ATOM 2136 C CB . ASP A 1 266 ? 30.519 120.579 29.958 1.00 18.37 ? 266 ASP M CB 1 ATOM 2137 C CG . ASP A 1 266 ? 29.756 121.741 29.502 1.00 25.44 ? 266 ASP M CG 1 ATOM 2138 O OD1 . ASP A 1 266 ? 29.715 122.089 28.314 1.00 22.07 ? 266 ASP M OD1 1 ATOM 2139 O OD2 . ASP A 1 266 ? 29.273 122.403 30.456 1.00 37.44 ? 266 ASP M OD2 1 ATOM 2140 N N . THR A 1 267 ? 30.673 119.600 26.540 1.00 12.23 ? 267 THR M N 1 ATOM 2141 C CA . THR A 1 267 ? 29.987 118.922 25.436 1.00 13.09 ? 267 THR M CA 1 ATOM 2142 C C . THR A 1 267 ? 30.896 118.053 24.636 1.00 13.79 ? 267 THR M C 1 ATOM 2143 O O . THR A 1 267 ? 30.496 117.597 23.544 1.00 15.96 ? 267 THR M O 1 ATOM 2144 C CB . THR A 1 267 ? 29.285 119.940 24.505 1.00 16.17 ? 267 THR M CB 1 ATOM 2145 O OG1 . THR A 1 267 ? 30.222 120.684 23.763 1.00 20.56 ? 267 THR M OG1 1 ATOM 2146 C CG2 . THR A 1 267 ? 28.327 120.718 25.284 1.00 17.94 ? 267 THR M CG2 1 ATOM 2147 N N . ASP A 1 268 ? 32.144 117.756 25.097 1.00 11.37 ? 268 ASP M N 1 ATOM 2148 C CA . ASP A 1 268 ? 33.107 116.972 24.431 1.00 9.95 ? 268 ASP M CA 1 ATOM 2149 C C . ASP A 1 268 ? 33.195 115.652 25.186 1.00 11.65 ? 268 ASP M C 1 ATOM 2150 O O . ASP A 1 268 ? 33.672 115.573 26.332 1.00 11.34 ? 268 ASP M O 1 ATOM 2151 C CB . ASP A 1 268 ? 34.478 117.618 24.364 1.00 12.74 ? 268 ASP M CB 1 ATOM 2152 C CG . ASP A 1 268 ? 35.627 116.656 23.942 1.00 13.92 ? 268 ASP M CG 1 ATOM 2153 O OD1 . ASP A 1 268 ? 35.497 115.599 23.328 1.00 22.62 ? 268 ASP M OD1 1 ATOM 2154 O OD2 . ASP A 1 268 ? 36.801 116.980 24.247 1.00 32.38 ? 268 ASP M OD2 1 ATOM 2155 N N . ARG A 1 269 ? 32.857 114.539 24.504 1.00 9.96 ? 269 ARG M N 1 ATOM 2156 C CA . ARG A 1 269 ? 32.893 113.238 25.200 1.00 8.89 ? 269 ARG M CA 1 ATOM 2157 C C . ARG A 1 269 ? 34.264 112.874 25.699 1.00 10.11 ? 269 ARG M C 1 ATOM 2158 O O . ARG A 1 269 ? 34.335 112.150 26.708 1.00 10.83 ? 269 ARG M O 1 ATOM 2159 C CB . ARG A 1 269 ? 32.324 112.149 24.268 1.00 11.87 ? 269 ARG M CB 1 ATOM 2160 C CG . ARG A 1 269 ? 33.213 111.857 23.138 1.00 13.98 ? 269 ARG M CG 1 ATOM 2161 C CD . ARG A 1 269 ? 32.510 110.791 22.265 1.00 19.20 ? 269 ARG M CD 1 ATOM 2162 N NE . ARG A 1 269 ? 33.291 110.483 21.080 1.00 17.22 ? 269 ARG M NE 1 ATOM 2163 C CZ . ARG A 1 269 ? 34.221 109.528 21.025 1.00 17.38 ? 269 ARG M CZ 1 ATOM 2164 N NH1 . ARG A 1 269 ? 34.590 108.798 22.053 1.00 19.80 ? 269 ARG M NH1 1 ATOM 2165 N NH2 . ARG A 1 269 ? 34.787 109.258 19.818 1.00 23.78 ? 269 ARG M NH2 1 ATOM 2166 N N . HIS A 1 270 ? 35.357 113.300 25.032 1.00 10.33 ? 270 HIS M N 1 ATOM 2167 C CA . HIS A 1 270 ? 36.690 112.950 25.467 1.00 9.84 ? 270 HIS M CA 1 ATOM 2168 C C . HIS A 1 270 ? 37.003 113.645 26.798 1.00 10.65 ? 270 HIS M C 1 ATOM 2169 O O . HIS A 1 270 ? 37.649 113.103 27.674 1.00 11.06 ? 270 HIS M O 1 ATOM 2170 C CB . HIS A 1 270 ? 37.696 113.269 24.424 1.00 12.51 ? 270 HIS M CB 1 ATOM 2171 C CG . HIS A 1 270 ? 37.459 112.556 23.116 1.00 14.03 ? 270 HIS M CG 1 ATOM 2172 N ND1 . HIS A 1 270 ? 37.615 111.192 22.973 1.00 17.65 ? 270 HIS M ND1 1 ATOM 2173 C CD2 . HIS A 1 270 ? 36.982 113.016 21.946 1.00 21.19 ? 270 HIS M CD2 1 ATOM 2174 C CE1 . HIS A 1 270 ? 37.367 110.871 21.700 1.00 18.82 ? 270 HIS M CE1 1 ATOM 2175 N NE2 . HIS A 1 270 ? 36.957 111.949 21.074 1.00 18.23 ? 270 HIS M NE2 1 ATOM 2176 N N . SER A 1 271 ? 36.622 114.899 26.925 1.00 9.03 ? 271 SER M N 1 ATOM 2177 C CA . SER A 1 271 ? 36.821 115.657 28.189 1.00 8.84 ? 271 SER M CA 1 ATOM 2178 C C . SER A 1 271 ? 35.958 115.070 29.287 1.00 9.35 ? 271 SER M C 1 ATOM 2179 O O . SER A 1 271 ? 36.403 114.986 30.420 1.00 9.10 ? 271 SER M O 1 ATOM 2180 C CB A SER A 1 271 ? 36.466 117.095 27.954 0.70 10.49 ? 271 SER M CB 1 ATOM 2181 C CB B SER A 1 271 ? 36.527 117.116 28.005 0.30 10.20 ? 271 SER M CB 1 ATOM 2182 O OG A SER A 1 271 ? 36.579 117.818 29.152 0.70 8.85 ? 271 SER M OG 1 ATOM 2183 O OG B SER A 1 271 ? 37.711 117.723 27.570 0.30 12.17 ? 271 SER M OG 1 ATOM 2184 N N . ILE A 1 272 ? 34.705 114.716 28.997 1.00 8.32 ? 272 ILE M N 1 ATOM 2185 C CA . ILE A 1 272 ? 33.815 114.038 29.938 1.00 9.12 ? 272 ILE M CA 1 ATOM 2186 C C . ILE A 1 272 ? 34.418 112.751 30.401 1.00 8.73 ? 272 ILE M C 1 ATOM 2187 O O . ILE A 1 272 ? 34.481 112.501 31.631 1.00 10.50 ? 272 ILE M O 1 ATOM 2188 C CB . ILE A 1 272 ? 32.448 113.898 29.326 1.00 10.00 ? 272 ILE M CB 1 ATOM 2189 C CG1 . ILE A 1 272 ? 31.802 115.236 29.079 1.00 10.82 ? 272 ILE M CG1 1 ATOM 2190 C CG2 . ILE A 1 272 ? 31.551 112.948 30.215 1.00 11.85 ? 272 ILE M CG2 1 ATOM 2191 C CD1 . ILE A 1 272 ? 30.513 115.179 28.189 1.00 12.77 ? 272 ILE M CD1 1 ATOM 2192 N N . ALA A 1 273 ? 34.973 111.941 29.526 1.00 8.11 ? 273 ALA M N 1 ATOM 2193 C CA . ALA A 1 273 ? 35.657 110.715 29.925 1.00 8.76 ? 273 ALA M CA 1 ATOM 2194 C C . ALA A 1 273 ? 36.880 110.963 30.801 1.00 9.17 ? 273 ALA M C 1 ATOM 2195 O O . ALA A 1 273 ? 37.098 110.240 31.751 1.00 10.43 ? 273 ALA M O 1 ATOM 2196 C CB . ALA A 1 273 ? 36.070 109.887 28.688 1.00 11.62 ? 273 ALA M CB 1 ATOM 2197 N N . ALA A 1 274 ? 37.690 111.979 30.452 1.00 8.55 ? 274 ALA M N 1 ATOM 2198 C CA . ALA A 1 274 ? 38.876 112.295 31.261 1.00 8.44 ? 274 ALA M CA 1 ATOM 2199 C C . ALA A 1 274 ? 38.452 112.733 32.606 1.00 8.20 ? 274 ALA M C 1 ATOM 2200 O O . ALA A 1 274 ? 39.188 112.388 33.591 1.00 9.34 ? 274 ALA M O 1 ATOM 2201 C CB . ALA A 1 274 ? 39.646 113.462 30.503 1.00 8.81 ? 274 ALA M CB 1 ATOM 2202 N N . THR A 1 275 ? 37.339 113.369 32.784 1.00 9.12 ? 275 THR M N 1 ATOM 2203 C CA . THR A 1 275 ? 36.824 113.842 34.072 1.00 7.84 ? 275 THR M CA 1 ATOM 2204 C C . THR A 1 275 ? 36.448 112.682 34.987 1.00 10.55 ? 275 THR M C 1 ATOM 2205 O O . THR A 1 275 ? 36.818 112.533 36.150 1.00 10.33 ? 275 THR M O 1 ATOM 2206 C CB . THR A 1 275 ? 35.660 114.786 33.890 1.00 9.46 ? 275 THR M CB 1 ATOM 2207 O OG1 . THR A 1 275 ? 36.100 115.867 33.045 1.00 9.69 ? 275 THR M OG1 1 ATOM 2208 C CG2 . THR A 1 275 ? 35.044 115.279 35.175 1.00 10.23 ? 275 THR M CG2 1 ATOM 2209 N N . GLU A 1 276 ? 35.814 111.675 34.339 1.00 9.58 ? 276 GLU M N 1 ATOM 2210 C CA . GLU A 1 276 ? 35.434 110.490 35.109 1.00 10.54 ? 276 GLU M CA 1 ATOM 2211 C C . GLU A 1 276 ? 36.659 109.670 35.415 1.00 10.77 ? 276 GLU M C 1 ATOM 2212 O O . GLU A 1 276 ? 36.755 109.067 36.532 1.00 11.10 ? 276 GLU M O 1 ATOM 2213 C CB . GLU A 1 276 ? 34.340 109.656 34.315 1.00 10.44 ? 276 GLU M CB 1 ATOM 2214 C CG . GLU A 1 276 ? 33.087 110.470 34.227 1.00 12.80 ? 276 GLU M CG 1 ATOM 2215 C CD . GLU A 1 276 ? 32.501 111.031 35.553 1.00 17.31 ? 276 GLU M CD 1 ATOM 2216 O OE1 . GLU A 1 276 ? 32.315 110.237 36.539 1.00 19.56 ? 276 GLU M OE1 1 ATOM 2217 O OE2 . GLU A 1 276 ? 32.339 112.240 35.678 1.00 16.68 ? 276 GLU M OE2 1 ATOM 2218 N N . ARG A 1 277 ? 37.661 109.622 34.545 1.00 9.59 ? 277 ARG M N 1 ATOM 2219 C CA . ARG A 1 277 ? 38.914 108.897 34.854 1.00 10.18 ? 277 ARG M CA 1 ATOM 2220 C C . ARG A 1 277 ? 39.556 109.552 36.066 1.00 11.02 ? 277 ARG M C 1 ATOM 2221 O O . ARG A 1 277 ? 40.150 108.859 36.928 1.00 11.24 ? 277 ARG M O 1 ATOM 2222 C CB . ARG A 1 277 ? 39.867 108.847 33.710 1.00 12.77 ? 277 ARG M CB 1 ATOM 2223 C CG . ARG A 1 277 ? 39.486 107.944 32.613 1.00 13.03 ? 277 ARG M CG 1 ATOM 2224 C CD . ARG A 1 277 ? 40.657 107.612 31.735 1.00 15.55 ? 277 ARG M CD 1 ATOM 2225 N NE . ARG A 1 277 ? 41.173 108.800 31.031 1.00 11.53 ? 277 ARG M NE 1 ATOM 2226 C CZ . ARG A 1 277 ? 40.708 109.295 29.879 1.00 12.58 ? 277 ARG M CZ 1 ATOM 2227 N NH1 . ARG A 1 277 ? 39.567 108.810 29.301 1.00 14.40 ? 277 ARG M NH1 1 ATOM 2228 N NH2 . ARG A 1 277 ? 41.236 110.394 29.351 1.00 14.90 ? 277 ARG M NH2 1 ATOM 2229 N N . MET A 1 278 ? 39.590 110.852 36.062 1.00 11.10 ? 278 MET M N 1 ATOM 2230 C CA . MET A 1 278 ? 40.197 111.553 37.172 1.00 10.49 ? 278 MET M CA 1 ATOM 2231 C C . MET A 1 278 ? 39.574 111.232 38.476 1.00 11.10 ? 278 MET M C 1 ATOM 2232 O O . MET A 1 278 ? 40.273 111.058 39.476 1.00 10.17 ? 278 MET M O 1 ATOM 2233 C CB . MET A 1 278 ? 40.201 113.063 37.052 1.00 12.33 ? 278 MET M CB 1 ATOM 2234 C CG . MET A 1 278 ? 41.219 113.504 36.176 1.00 14.03 ? 278 MET M CG 1 ATOM 2235 S SD . MET A 1 278 ? 42.954 113.096 36.631 1.00 12.99 ? 278 MET M SD 1 ATOM 2236 C CE . MET A 1 278 ? 43.105 113.549 38.328 1.00 15.18 ? 278 MET M CE 1 ATOM 2237 N N . LYS A 1 279 ? 38.245 111.089 38.541 1.00 9.07 ? 279 LYS M N 1 ATOM 2238 C CA . LYS A 1 279 ? 37.600 110.737 39.769 1.00 9.59 ? 279 LYS M CA 1 ATOM 2239 C C . LYS A 1 279 ? 38.122 109.358 40.213 1.00 10.51 ? 279 LYS M C 1 ATOM 2240 O O . LYS A 1 279 ? 38.407 109.136 41.419 1.00 10.37 ? 279 LYS M O 1 ATOM 2241 C CB . LYS A 1 279 ? 36.075 110.694 39.640 1.00 10.21 ? 279 LYS M CB 1 ATOM 2242 C CG . LYS A 1 279 ? 35.550 112.115 39.355 1.00 11.06 ? 279 LYS M CG 1 ATOM 2243 C CD . LYS A 1 279 ? 34.043 112.164 39.038 1.00 11.09 ? 279 LYS M CD 1 ATOM 2244 C CE . LYS A 1 279 ? 33.647 113.553 38.601 1.00 11.69 ? 279 LYS M CE 1 ATOM 2245 N NZ . LYS A 1 279 ? 32.202 113.596 38.028 1.00 12.59 ? 279 LYS M NZ 1 ATOM 2246 N N . GLU A 1 280 ? 38.205 108.428 39.305 1.00 9.24 ? 280 GLU M N 1 ATOM 2247 C CA . GLU A 1 280 ? 38.659 107.076 39.666 1.00 8.77 ? 280 GLU M CA 1 ATOM 2248 C C . GLU A 1 280 ? 40.112 107.050 40.069 1.00 7.74 ? 280 GLU M C 1 ATOM 2249 O O . GLU A 1 280 ? 40.543 106.342 41.011 1.00 10.24 ? 280 GLU M O 1 ATOM 2250 C CB . GLU A 1 280 ? 38.417 106.108 38.473 1.00 10.18 ? 280 GLU M CB 1 ATOM 2251 C CG . GLU A 1 280 ? 36.958 105.829 38.347 1.00 13.27 ? 280 GLU M CG 1 ATOM 2252 C CD . GLU A 1 280 ? 36.418 104.858 39.376 1.00 18.08 ? 280 GLU M CD 1 ATOM 2253 O OE1 . GLU A 1 280 ? 36.241 105.218 40.559 1.00 19.17 ? 280 GLU M OE1 1 ATOM 2254 O OE2 . GLU A 1 280 ? 36.203 103.625 39.127 1.00 19.37 ? 280 GLU M OE2 1 ATOM 2255 N N . PHE A 1 281 ? 40.967 107.775 39.339 1.00 7.90 ? 281 PHE M N 1 ATOM 2256 C CA . PHE A 1 281 ? 42.412 107.769 39.614 1.00 8.55 ? 281 PHE M CA 1 ATOM 2257 C C . PHE A 1 281 ? 42.811 108.557 40.823 1.00 9.94 ? 281 PHE M C 1 ATOM 2258 O O . PHE A 1 281 ? 43.859 108.217 41.441 1.00 11.72 ? 281 PHE M O 1 ATOM 2259 C CB . PHE A 1 281 ? 43.203 108.253 38.418 1.00 8.73 ? 281 PHE M CB 1 ATOM 2260 C CG . PHE A 1 281 ? 43.565 107.118 37.428 1.00 10.50 ? 281 PHE M CG 1 ATOM 2261 C CD1 . PHE A 1 281 ? 42.665 106.739 36.448 1.00 9.83 ? 281 PHE M CD1 1 ATOM 2262 C CD2 . PHE A 1 281 ? 44.783 106.464 37.476 1.00 12.31 ? 281 PHE M CD2 1 ATOM 2263 C CE1 . PHE A 1 281 ? 43.004 105.739 35.490 1.00 14.21 ? 281 PHE M CE1 1 ATOM 2264 C CE2 . PHE A 1 281 ? 45.087 105.475 36.517 1.00 15.21 ? 281 PHE M CE2 1 ATOM 2265 C CZ . PHE A 1 281 ? 44.210 105.109 35.627 1.00 12.41 ? 281 PHE M CZ 1 ATOM 2266 N N . PHE A 1 282 ? 42.060 109.614 41.146 1.00 8.10 ? 282 PHE M N 1 ATOM 2267 C CA . PHE A 1 282 ? 42.427 110.504 42.281 1.00 7.37 ? 282 PHE M CA 1 ATOM 2268 C C . PHE A 1 282 ? 41.736 109.991 43.522 1.00 8.68 ? 282 PHE M C 1 ATOM 2269 O O . PHE A 1 282 ? 42.373 109.948 44.564 1.00 9.69 ? 282 PHE M O 1 ATOM 2270 C CB . PHE A 1 282 ? 42.062 111.927 41.922 1.00 9.23 ? 282 PHE M CB 1 ATOM 2271 C CG . PHE A 1 282 ? 42.560 112.954 42.888 1.00 8.95 ? 282 PHE M CG 1 ATOM 2272 C CD1 . PHE A 1 282 ? 43.819 113.475 42.710 1.00 9.24 ? 282 PHE M CD1 1 ATOM 2273 C CD2 . PHE A 1 282 ? 41.795 113.391 43.954 1.00 8.50 ? 282 PHE M CD2 1 ATOM 2274 C CE1 . PHE A 1 282 ? 44.291 114.396 43.614 1.00 13.05 ? 282 PHE M CE1 1 ATOM 2275 C CE2 . PHE A 1 282 ? 42.285 114.326 44.837 1.00 9.37 ? 282 PHE M CE2 1 ATOM 2276 C CZ . PHE A 1 282 ? 43.517 114.827 44.628 1.00 11.50 ? 282 PHE M CZ 1 ATOM 2277 N N . LEU A 1 283 ? 40.411 109.760 43.502 1.00 7.99 ? 283 LEU M N 1 ATOM 2278 C CA . LEU A 1 283 ? 39.648 109.327 44.676 1.00 8.06 ? 283 LEU M CA 1 ATOM 2279 C C . LEU A 1 283 ? 39.578 107.771 44.736 1.00 8.47 ? 283 LEU M C 1 ATOM 2280 O O . LEU A 1 283 ? 39.782 107.212 45.804 1.00 9.09 ? 283 LEU M O 1 ATOM 2281 C CB . LEU A 1 283 ? 38.225 109.960 44.623 1.00 9.58 ? 283 LEU M CB 1 ATOM 2282 C CG . LEU A 1 283 ? 38.148 111.467 44.498 1.00 10.35 ? 283 LEU M CG 1 ATOM 2283 C CD1 . LEU A 1 283 ? 36.688 111.944 44.218 1.00 12.70 ? 283 LEU M CD1 1 ATOM 2284 C CD2 . LEU A 1 283 ? 38.702 112.108 45.773 1.00 11.21 ? 283 LEU M CD2 1 ATOM 2285 N N . GLY A 1 284 ? 39.228 107.152 43.605 1.00 8.62 ? 284 GLY M N 1 ATOM 2286 C CA . GLY A 1 284 ? 38.950 105.731 43.600 1.00 9.56 ? 284 GLY M CA 1 ATOM 2287 C C . GLY A 1 284 ? 40.189 104.893 43.897 1.00 8.16 ? 284 GLY M C 1 ATOM 2288 O O . GLY A 1 284 ? 40.079 103.757 44.382 1.00 9.01 ? 284 GLY M O 1 ATOM 2289 N N . TRP A 1 285 ? 41.419 105.411 43.579 1.00 7.49 ? 285 TRP M N 1 ATOM 2290 C CA . TRP A 1 285 ? 42.623 104.694 43.906 1.00 7.89 ? 285 TRP M CA 1 ATOM 2291 C C . TRP A 1 285 ? 42.590 104.151 45.317 1.00 8.02 ? 285 TRP M C 1 ATOM 2292 O O . TRP A 1 285 ? 43.091 103.078 45.610 1.00 8.46 ? 285 TRP M O 1 ATOM 2293 C CB . TRP A 1 285 ? 43.814 105.630 43.655 1.00 6.66 ? 285 TRP M CB 1 ATOM 2294 C CG . TRP A 1 285 ? 45.167 105.111 43.709 1.00 7.05 ? 285 TRP M CG 1 ATOM 2295 C CD1 . TRP A 1 285 ? 45.615 103.803 43.881 1.00 8.65 ? 285 TRP M CD1 1 ATOM 2296 C CD2 . TRP A 1 285 ? 46.342 105.904 43.489 1.00 7.77 ? 285 TRP M CD2 1 ATOM 2297 N NE1 . TRP A 1 285 ? 46.970 103.746 43.822 1.00 8.93 ? 285 TRP M NE1 1 ATOM 2298 C CE2 . TRP A 1 285 ? 47.441 105.025 43.598 1.00 7.74 ? 285 TRP M CE2 1 ATOM 2299 C CE3 . TRP A 1 285 ? 46.561 107.238 43.276 1.00 10.62 ? 285 TRP M CE3 1 ATOM 2300 C CZ2 . TRP A 1 285 ? 48.758 105.434 43.468 1.00 7.55 ? 285 TRP M CZ2 1 ATOM 2301 C CZ3 . TRP A 1 285 ? 47.900 107.679 43.189 1.00 12.04 ? 285 TRP M CZ3 1 ATOM 2302 C CH2 . TRP A 1 285 ? 48.964 106.771 43.254 1.00 8.40 ? 285 TRP M CH2 1 ATOM 2303 N N . PHE A 1 286 ? 42.102 104.998 46.251 1.00 8.02 ? 286 PHE M N 1 ATOM 2304 C CA . PHE A 1 286 ? 42.009 104.604 47.641 1.00 7.54 ? 286 PHE M CA 1 ATOM 2305 C C . PHE A 1 286 ? 40.611 104.184 48.054 1.00 7.80 ? 286 PHE M C 1 ATOM 2306 O O . PHE A 1 286 ? 40.445 103.290 48.869 1.00 8.78 ? 286 PHE M O 1 ATOM 2307 C CB . PHE A 1 286 ? 42.548 105.772 48.481 1.00 9.73 ? 286 PHE M CB 1 ATOM 2308 C CG . PHE A 1 286 ? 43.932 106.128 48.103 1.00 8.56 ? 286 PHE M CG 1 ATOM 2309 C CD1 . PHE A 1 286 ? 44.959 105.341 48.538 1.00 9.35 ? 286 PHE M CD1 1 ATOM 2310 C CD2 . PHE A 1 286 ? 44.213 107.138 47.271 1.00 9.82 ? 286 PHE M CD2 1 ATOM 2311 C CE1 . PHE A 1 286 ? 46.289 105.555 48.133 1.00 10.11 ? 286 PHE M CE1 1 ATOM 2312 C CE2 . PHE A 1 286 ? 45.518 107.356 46.827 1.00 10.50 ? 286 PHE M CE2 1 ATOM 2313 C CZ . PHE A 1 286 ? 46.551 106.547 47.260 1.00 10.21 ? 286 PHE M CZ 1 ATOM 2314 N N . MET A 1 287 ? 39.563 104.868 47.578 1.00 9.41 ? 287 MET M N 1 ATOM 2315 C CA . MET A 1 287 ? 38.219 104.619 47.985 1.00 8.55 ? 287 MET M CA 1 ATOM 2316 C C . MET A 1 287 ? 37.684 103.266 47.446 1.00 8.03 ? 287 MET M C 1 ATOM 2317 O O . MET A 1 287 ? 36.802 102.635 48.075 1.00 9.16 ? 287 MET M O 1 ATOM 2318 C CB . MET A 1 287 ? 37.284 105.789 47.630 1.00 8.44 ? 287 MET M CB 1 ATOM 2319 C CG . MET A 1 287 ? 37.528 107.013 48.448 1.00 10.08 ? 287 MET M CG 1 ATOM 2320 S SD . MET A 1 287 ? 37.525 106.795 50.227 1.00 11.78 ? 287 MET M SD 1 ATOM 2321 C CE . MET A 1 287 ? 35.870 106.131 50.507 1.00 13.99 ? 287 MET M CE 1 ATOM 2322 N N . GLY A 1 288 ? 38.190 102.856 46.307 1.00 9.45 ? 288 GLY M N 1 ATOM 2323 C CA . GLY A 1 288 ? 37.845 101.525 45.765 1.00 9.46 ? 288 GLY M CA 1 ATOM 2324 C C . GLY A 1 288 ? 38.276 100.464 46.741 1.00 8.47 ? 288 GLY M C 1 ATOM 2325 O O . GLY A 1 288 ? 37.489 99.668 47.249 1.00 10.30 ? 288 GLY M O 1 ATOM 2326 N N . PRO A 1 289 ? 39.569 100.471 47.118 1.00 7.23 ? 289 PRO M N 1 ATOM 2327 C CA . PRO A 1 289 ? 40.059 99.518 48.150 1.00 6.73 ? 289 PRO M CA 1 ATOM 2328 C C . PRO A 1 289 ? 39.292 99.602 49.450 1.00 8.01 ? 289 PRO M C 1 ATOM 2329 O O . PRO A 1 289 ? 38.872 98.641 50.088 1.00 9.30 ? 289 PRO M O 1 ATOM 2330 C CB . PRO A 1 289 ? 41.536 99.779 48.252 1.00 10.26 ? 289 PRO M CB 1 ATOM 2331 C CG . PRO A 1 289 ? 41.885 100.222 46.816 1.00 9.28 ? 289 PRO M CG 1 ATOM 2332 C CD . PRO A 1 289 ? 40.723 101.009 46.390 1.00 7.03 ? 289 PRO M CD 1 ATOM 2333 N N . LEU A 1 290 ? 39.096 100.865 49.959 1.00 8.09 ? 290 LEU M N 1 ATOM 2334 C CA . LEU A 1 290 ? 38.419 101.081 51.231 1.00 8.88 ? 290 LEU M CA 1 ATOM 2335 C C . LEU A 1 290 ? 36.958 100.642 51.278 1.00 10.73 ? 290 LEU M C 1 ATOM 2336 O O . LEU A 1 290 ? 36.474 100.270 52.332 1.00 10.89 ? 290 LEU M O 1 ATOM 2337 C CB . LEU A 1 290 ? 38.525 102.560 51.661 1.00 7.62 ? 290 LEU M CB 1 ATOM 2338 C CG . LEU A 1 290 ? 39.977 102.951 52.028 1.00 11.19 ? 290 LEU M CG 1 ATOM 2339 C CD1 . LEU A 1 290 ? 40.021 104.445 52.104 1.00 11.35 ? 290 LEU M CD1 1 ATOM 2340 C CD2 . LEU A 1 290 ? 40.479 102.299 53.330 1.00 11.90 ? 290 LEU M CD2 1 ATOM 2341 N N . THR A 1 291 ? 36.305 100.595 50.124 1.00 10.04 ? 291 THR M N 1 ATOM 2342 C CA . THR A 1 291 ? 34.860 100.247 50.082 1.00 9.51 ? 291 THR M CA 1 ATOM 2343 C C . THR A 1 291 ? 34.636 98.909 49.415 1.00 12.16 ? 291 THR M C 1 ATOM 2344 O O . THR A 1 291 ? 33.596 98.310 49.723 1.00 14.49 ? 291 THR M O 1 ATOM 2345 C CB . THR A 1 291 ? 34.041 101.272 49.363 1.00 10.10 ? 291 THR M CB 1 ATOM 2346 O OG1 . THR A 1 291 ? 34.444 101.464 47.999 1.00 11.22 ? 291 THR M OG1 1 ATOM 2347 C CG2 . THR A 1 291 ? 34.029 102.686 50.111 1.00 12.79 ? 291 THR M CG2 1 ATOM 2348 N N . ASN A 1 292 ? 35.578 98.406 48.638 1.00 14.00 ? 292 ASN M N 1 ATOM 2349 C CA . ASN A 1 292 ? 35.315 97.162 47.835 1.00 13.06 ? 292 ASN M CA 1 ATOM 2350 C C . ASN A 1 292 ? 36.418 96.188 47.982 1.00 13.32 ? 292 ASN M C 1 ATOM 2351 O O . ASN A 1 292 ? 36.297 95.062 47.539 1.00 14.67 ? 292 ASN M O 1 ATOM 2352 C CB . ASN A 1 292 ? 35.059 97.523 46.407 1.00 14.17 ? 292 ASN M CB 1 ATOM 2353 C CG . ASN A 1 292 ? 34.399 96.377 45.586 1.00 16.32 ? 292 ASN M CG 1 ATOM 2354 O OD1 . ASN A 1 292 ? 33.336 95.893 46.081 1.00 21.59 ? 292 ASN M OD1 1 ATOM 2355 N ND2 . ASN A 1 292 ? 35.123 95.870 44.595 1.00 15.07 ? 292 ASN M ND2 1 ATOM 2356 N N . GLY A 1 293 ? 37.593 96.517 48.502 1.00 10.96 ? 293 GLY M N 1 ATOM 2357 C CA . GLY A 1 293 ? 38.742 95.710 48.562 1.00 11.42 ? 293 GLY M CA 1 ATOM 2358 C C . GLY A 1 293 ? 39.489 95.517 47.257 1.00 10.90 ? 293 GLY M C 1 ATOM 2359 O O . GLY A 1 293 ? 40.360 94.652 47.211 1.00 13.02 ? 293 GLY M O 1 ATOM 2360 N N . THR A 1 294 ? 39.203 96.360 46.251 1.00 11.33 ? 294 THR M N 1 ATOM 2361 C CA . THR A 1 294 ? 39.861 96.256 44.955 1.00 9.66 ? 294 THR M CA 1 ATOM 2362 C C . THR A 1 294 ? 40.067 97.667 44.414 1.00 8.84 ? 294 THR M C 1 ATOM 2363 O O . THR A 1 294 ? 39.323 98.583 44.761 1.00 11.81 ? 294 THR M O 1 ATOM 2364 C CB . THR A 1 294 ? 38.989 95.543 43.941 1.00 12.38 ? 294 THR M CB 1 ATOM 2365 O OG1 . THR A 1 294 ? 37.810 96.286 43.726 1.00 14.38 ? 294 THR M OG1 1 ATOM 2366 C CG2 . THR A 1 294 ? 38.743 94.053 44.379 1.00 15.33 ? 294 THR M CG2 1 ATOM 2367 N N . TYR A 1 295 ? 41.104 97.814 43.562 1.00 9.92 ? 295 TYR M N 1 ATOM 2368 C CA . TYR A 1 295 ? 41.297 99.008 42.844 1.00 9.32 ? 295 TYR M CA 1 ATOM 2369 C C . TYR A 1 295 ? 40.237 99.191 41.758 1.00 11.17 ? 295 TYR M C 1 ATOM 2370 O O . TYR A 1 295 ? 39.644 98.194 41.230 1.00 11.51 ? 295 TYR M O 1 ATOM 2371 C CB . TYR A 1 295 ? 42.691 99.071 42.220 1.00 9.31 ? 295 TYR M CB 1 ATOM 2372 C CG . TYR A 1 295 ? 43.827 99.137 43.172 1.00 7.34 ? 295 TYR M CG 1 ATOM 2373 C CD1 . TYR A 1 295 ? 43.926 100.266 43.999 1.00 7.95 ? 295 TYR M CD1 1 ATOM 2374 C CD2 . TYR A 1 295 ? 44.725 98.125 43.356 1.00 8.69 ? 295 TYR M CD2 1 ATOM 2375 C CE1 . TYR A 1 295 ? 44.952 100.319 44.884 1.00 9.14 ? 295 TYR M CE1 1 ATOM 2376 C CE2 . TYR A 1 295 ? 45.769 98.173 44.220 1.00 10.21 ? 295 TYR M CE2 1 ATOM 2377 C CZ . TYR A 1 295 ? 45.890 99.327 45.026 1.00 10.52 ? 295 TYR M CZ 1 ATOM 2378 O OH . TYR A 1 295 ? 46.920 99.435 45.941 1.00 10.17 ? 295 TYR M OH 1 ATOM 2379 N N . PRO A 1 296 ? 39.954 100.456 41.356 1.00 10.46 ? 296 PRO M N 1 ATOM 2380 C CA . PRO A 1 296 ? 39.032 100.640 40.226 1.00 10.45 ? 296 PRO M CA 1 ATOM 2381 C C . PRO A 1 296 ? 39.444 99.906 38.958 1.00 8.92 ? 296 PRO M C 1 ATOM 2382 O O . PRO A 1 296 ? 40.560 99.804 38.640 1.00 9.45 ? 296 PRO M O 1 ATOM 2383 C CB . PRO A 1 296 ? 39.070 102.098 39.980 1.00 11.66 ? 296 PRO M CB 1 ATOM 2384 C CG . PRO A 1 296 ? 39.513 102.675 41.315 1.00 9.74 ? 296 PRO M CG 1 ATOM 2385 C CD . PRO A 1 296 ? 40.526 101.732 41.824 1.00 9.72 ? 296 PRO M CD 1 ATOM 2386 N N . GLN A 1 297 ? 38.395 99.476 38.241 1.00 11.13 ? 297 GLN M N 1 ATOM 2387 C CA . GLN A 1 297 ? 38.721 98.713 37.003 1.00 11.48 ? 297 GLN M CA 1 ATOM 2388 C C . GLN A 1 297 ? 39.476 99.471 36.033 1.00 10.54 ? 297 GLN M C 1 ATOM 2389 O O . GLN A 1 297 ? 40.409 98.961 35.371 1.00 11.04 ? 297 GLN M O 1 ATOM 2390 C CB . GLN A 1 297 ? 37.375 98.300 36.393 1.00 12.29 ? 297 GLN M CB 1 ATOM 2391 C CG . GLN A 1 297 ? 37.645 97.339 35.237 1.00 11.15 ? 297 GLN M CG 1 ATOM 2392 C CD . GLN A 1 297 ? 38.194 96.010 35.695 1.00 12.09 ? 297 GLN M CD 1 ATOM 2393 O OE1 . GLN A 1 297 ? 37.743 95.382 36.706 1.00 16.98 ? 297 GLN M OE1 1 ATOM 2394 N NE2 . GLN A 1 297 ? 39.275 95.560 34.986 1.00 17.87 ? 297 GLN M NE2 1 ATOM 2395 N N . ILE A 1 298 ? 39.244 100.758 35.860 1.00 10.23 ? 298 ILE M N 1 ATOM 2396 C CA . ILE A 1 298 ? 39.991 101.574 34.909 1.00 12.70 ? 298 ILE M CA 1 ATOM 2397 C C . ILE A 1 298 ? 41.482 101.581 35.283 1.00 13.13 ? 298 ILE M C 1 ATOM 2398 O O . ILE A 1 298 ? 42.381 101.591 34.425 1.00 12.61 ? 298 ILE M O 1 ATOM 2399 C CB . ILE A 1 298 ? 39.487 103.000 34.676 1.00 11.87 ? 298 ILE M CB 1 ATOM 2400 C CG1 . ILE A 1 298 ? 40.153 103.749 33.532 1.00 16.35 ? 298 ILE M CG1 1 ATOM 2401 C CG2 . ILE A 1 298 ? 39.492 103.867 35.974 1.00 10.69 ? 298 ILE M CG2 1 ATOM 2402 C CD1 . ILE A 1 298 ? 40.115 102.993 32.175 1.00 19.35 ? 298 ILE M CD1 1 ATOM 2403 N N . MET A 1 299 ? 41.755 101.599 36.589 1.00 11.48 ? 299 MET M N 1 ATOM 2404 C CA . MET A 1 299 ? 43.132 101.502 37.013 1.00 9.89 ? 299 MET M CA 1 ATOM 2405 C C . MET A 1 299 ? 43.771 100.143 36.760 1.00 10.13 ? 299 MET M C 1 ATOM 2406 O O . MET A 1 299 ? 44.917 100.003 36.277 1.00 10.82 ? 299 MET M O 1 ATOM 2407 C CB . MET A 1 299 ? 43.363 101.889 38.486 1.00 10.46 ? 299 MET M CB 1 ATOM 2408 C CG . MET A 1 299 ? 42.973 103.256 38.756 1.00 9.83 ? 299 MET M CG 1 ATOM 2409 S SD . MET A 1 299 ? 43.431 103.856 40.449 1.00 10.81 ? 299 MET M SD 1 ATOM 2410 C CE . MET A 1 299 ? 45.252 103.836 40.259 1.00 13.16 ? 299 MET M CE 1 ATOM 2411 N N . ILE A 1 300 ? 43.019 99.077 37.050 1.00 10.69 ? 300 ILE M N 1 ATOM 2412 C CA . ILE A 1 300 ? 43.453 97.684 36.754 1.00 11.55 ? 300 ILE M CA 1 ATOM 2413 C C . ILE A 1 300 ? 43.822 97.595 35.265 1.00 11.94 ? 300 ILE M C 1 ATOM 2414 O O . ILE A 1 300 ? 44.910 97.125 34.908 1.00 13.81 ? 300 ILE M O 1 ATOM 2415 C CB . ILE A 1 300 ? 42.377 96.736 37.153 1.00 10.82 ? 300 ILE M CB 1 ATOM 2416 C CG1 . ILE A 1 300 ? 42.179 96.636 38.642 1.00 13.89 ? 300 ILE M CG1 1 ATOM 2417 C CG2 . ILE A 1 300 ? 42.780 95.342 36.624 1.00 13.63 ? 300 ILE M CG2 1 ATOM 2418 C CD1 . ILE A 1 300 ? 41.045 95.868 39.177 1.00 13.26 ? 300 ILE M CD1 1 ATOM 2419 N N . ASP A 1 301 ? 42.958 98.156 34.416 1.00 12.70 ? 301 ASP M N 1 ATOM 2420 C CA . ASP A 1 301 ? 43.109 98.029 32.950 1.00 14.92 ? 301 ASP M CA 1 ATOM 2421 C C . ASP A 1 301 ? 44.321 98.855 32.470 1.00 14.74 ? 301 ASP M C 1 ATOM 2422 O O . ASP A 1 301 ? 45.173 98.409 31.648 1.00 18.35 ? 301 ASP M O 1 ATOM 2423 C CB . ASP A 1 301 ? 41.877 98.520 32.221 1.00 16.09 ? 301 ASP M CB 1 ATOM 2424 C CG . ASP A 1 301 ? 40.613 97.658 32.443 1.00 21.86 ? 301 ASP M CG 1 ATOM 2425 O OD1 . ASP A 1 301 ? 40.742 96.546 32.843 1.00 24.38 ? 301 ASP M OD1 1 ATOM 2426 O OD2 . ASP A 1 301 ? 39.541 98.258 32.059 1.00 27.97 ? 301 ASP M OD2 1 ATOM 2427 N N . THR A 1 302 ? 44.522 100.071 32.986 1.00 11.69 ? 302 THR M N 1 ATOM 2428 C CA . THR A 1 302 ? 45.473 100.991 32.468 1.00 11.39 ? 302 THR M CA 1 ATOM 2429 C C . THR A 1 302 ? 46.856 100.695 33.020 1.00 13.64 ? 302 THR M C 1 ATOM 2430 O O . THR A 1 302 ? 47.871 100.749 32.281 1.00 15.27 ? 302 THR M O 1 ATOM 2431 C CB . THR A 1 302 ? 45.101 102.460 32.799 1.00 13.41 ? 302 THR M CB 1 ATOM 2432 O OG1 . THR A 1 302 ? 43.839 102.807 32.146 1.00 16.99 ? 302 THR M OG1 1 ATOM 2433 C CG2 . THR A 1 302 ? 46.123 103.429 32.285 1.00 17.41 ? 302 THR M CG2 1 ATOM 2434 N N . VAL A 1 303 ? 46.917 100.492 34.344 1.00 13.31 ? 303 VAL M N 1 ATOM 2435 C CA . VAL A 1 303 ? 48.189 100.402 35.043 1.00 12.06 ? 303 VAL M CA 1 ATOM 2436 C C . VAL A 1 303 ? 48.787 98.999 34.891 1.00 12.47 ? 303 VAL M C 1 ATOM 2437 O O . VAL A 1 303 ? 49.985 98.795 35.000 1.00 14.14 ? 303 VAL M O 1 ATOM 2438 C CB . VAL A 1 303 ? 47.982 100.813 36.480 1.00 11.91 ? 303 VAL M CB 1 ATOM 2439 C CG1 . VAL A 1 303 ? 49.281 100.802 37.274 1.00 13.62 ? 303 VAL M CG1 1 ATOM 2440 C CG2 . VAL A 1 303 ? 47.423 102.249 36.540 1.00 10.75 ? 303 VAL M CG2 1 ATOM 2441 N N . GLY A 1 304 ? 47.898 98.004 34.718 1.00 14.45 ? 304 GLY M N 1 ATOM 2442 C CA . GLY A 1 304 ? 48.372 96.607 34.381 1.00 15.05 ? 304 GLY M CA 1 ATOM 2443 C C . GLY A 1 304 ? 49.343 96.057 35.434 1.00 14.19 ? 304 GLY M C 1 ATOM 2444 O O . GLY A 1 304 ? 49.028 96.101 36.649 1.00 12.79 ? 304 GLY M O 1 ATOM 2445 N N . GLU A 1 305 ? 50.506 95.604 34.967 1.00 15.01 ? 305 GLU M N 1 ATOM 2446 C CA . GLU A 1 305 ? 51.393 94.870 35.846 1.00 16.57 ? 305 GLU M CA 1 ATOM 2447 C C . GLU A 1 305 ? 52.017 95.800 36.862 1.00 14.93 ? 305 GLU M C 1 ATOM 2448 O O . GLU A 1 305 ? 52.599 95.286 37.851 1.00 15.82 ? 305 GLU M O 1 ATOM 2449 C CB A GLU A 1 305 ? 52.565 94.234 35.035 0.70 18.50 ? 305 GLU M CB 1 ATOM 2450 C CB B GLU A 1 305 ? 52.483 94.160 35.039 0.30 16.60 ? 305 GLU M CB 1 ATOM 2451 C CG A GLU A 1 305 ? 53.525 93.388 35.913 0.70 29.76 ? 305 GLU M CG 1 ATOM 2452 C CG B GLU A 1 305 ? 51.927 93.089 34.116 0.30 19.11 ? 305 GLU M CG 1 ATOM 2453 C CD A GLU A 1 305 ? 54.936 93.166 35.343 0.70 88.54 ? 305 GLU M CD 1 ATOM 2454 C CD B GLU A 1 305 ? 51.172 92.009 34.843 0.30 24.64 ? 305 GLU M CD 1 ATOM 2455 O OE1 A GLU A 1 305 ? 55.122 93.166 34.107 0.70 41.72 ? 305 GLU M OE1 1 ATOM 2456 O OE1 B GLU A 1 305 ? 51.557 91.634 35.978 0.30 29.38 ? 305 GLU M OE1 1 ATOM 2457 O OE2 A GLU A 1 305 ? 55.866 92.968 36.166 0.70 44.17 ? 305 GLU M OE2 1 ATOM 2458 O OE2 B GLU A 1 305 ? 50.187 91.486 34.285 0.30 29.58 ? 305 GLU M OE2 1 ATOM 2459 N N . ARG A 1 306 ? 51.880 97.105 36.680 1.00 12.76 ? 306 ARG M N 1 ATOM 2460 C CA . ARG A 1 306 ? 52.439 98.104 37.685 1.00 12.14 ? 306 ARG M CA 1 ATOM 2461 C C . ARG A 1 306 ? 51.508 98.213 38.902 1.00 12.25 ? 306 ARG M C 1 ATOM 2462 O O . ARG A 1 306 ? 51.923 98.797 39.924 1.00 12.30 ? 306 ARG M O 1 ATOM 2463 C CB . ARG A 1 306 ? 52.767 99.438 37.085 1.00 11.39 ? 306 ARG M CB 1 ATOM 2464 C CG . ARG A 1 306 ? 53.883 99.464 36.082 1.00 11.54 ? 306 ARG M CG 1 ATOM 2465 C CD . ARG A 1 306 ? 54.265 100.773 35.451 1.00 12.86 ? 306 ARG M CD 1 ATOM 2466 N NE . ARG A 1 306 ? 53.231 101.119 34.547 1.00 12.46 ? 306 ARG M NE 1 ATOM 2467 C CZ . ARG A 1 306 ? 52.410 102.168 34.621 1.00 12.84 ? 306 ARG M CZ 1 ATOM 2468 N NH1 . ARG A 1 306 ? 52.514 103.115 35.546 1.00 11.67 ? 306 ARG M NH1 1 ATOM 2469 N NH2 . ARG A 1 306 ? 51.433 102.304 33.710 1.00 13.37 ? 306 ARG M NH2 1 ATOM 2470 N N . LEU A 1 307 ? 50.315 97.703 38.841 1.00 11.75 ? 307 LEU M N 1 ATOM 2471 C CA . LEU A 1 307 ? 49.345 97.892 39.944 1.00 11.17 ? 307 LEU M CA 1 ATOM 2472 C C . LEU A 1 307 ? 49.418 96.635 40.797 1.00 14.37 ? 307 LEU M C 1 ATOM 2473 O O . LEU A 1 307 ? 49.049 95.549 40.343 1.00 14.51 ? 307 LEU M O 1 ATOM 2474 C CB . LEU A 1 307 ? 47.940 98.112 39.404 1.00 12.55 ? 307 LEU M CB 1 ATOM 2475 C CG . LEU A 1 307 ? 46.921 98.571 40.392 1.00 11.34 ? 307 LEU M CG 1 ATOM 2476 C CD1 . LEU A 1 307 ? 47.241 99.947 40.961 1.00 11.61 ? 307 LEU M CD1 1 ATOM 2477 C CD2 . LEU A 1 307 ? 45.482 98.489 39.756 1.00 12.25 ? 307 LEU M CD2 1 ATOM 2478 N N . PRO A 1 308 ? 49.802 96.738 42.063 1.00 11.16 ? 308 PRO M N 1 ATOM 2479 C CA . PRO A 1 308 ? 49.801 95.552 42.931 1.00 13.63 ? 308 PRO M CA 1 ATOM 2480 C C . PRO A 1 308 ? 48.441 94.931 43.195 1.00 13.62 ? 308 PRO M C 1 ATOM 2481 O O . PRO A 1 308 ? 47.396 95.550 43.039 1.00 14.01 ? 308 PRO M O 1 ATOM 2482 C CB . PRO A 1 308 ? 50.361 96.094 44.267 1.00 15.20 ? 308 PRO M CB 1 ATOM 2483 C CG . PRO A 1 308 ? 51.085 97.338 43.943 1.00 15.15 ? 308 PRO M CG 1 ATOM 2484 C CD . PRO A 1 308 ? 50.252 97.962 42.802 1.00 11.93 ? 308 PRO M CD 1 ATOM 2485 N N . SER A 1 309 ? 48.476 93.605 43.429 1.00 19.45 ? 309 SER M N 1 ATOM 2486 C CA . SER A 1 309 ? 47.277 92.891 43.791 1.00 20.21 ? 309 SER M CA 1 ATOM 2487 C C . SER A 1 309 ? 47.097 92.761 45.299 1.00 18.68 ? 309 SER M C 1 ATOM 2488 O O . SER A 1 309 ? 48.096 92.682 45.991 1.00 18.05 ? 309 SER M O 1 ATOM 2489 C CB A SER A 1 309 ? 47.269 91.506 43.148 0.50 21.60 ? 309 SER M CB 1 ATOM 2490 C CB B SER A 1 309 ? 47.383 91.430 43.228 0.50 20.78 ? 309 SER M CB 1 ATOM 2491 O OG A SER A 1 309 ? 48.534 90.968 43.325 0.50 24.22 ? 309 SER M OG 1 ATOM 2492 O OG B SER A 1 309 ? 47.775 91.378 41.855 0.50 23.17 ? 309 SER M OG 1 ATOM 2493 N N . PHE A 1 310 ? 45.855 92.703 45.753 1.00 17.99 ? 310 PHE M N 1 ATOM 2494 C CA . PHE A 1 310 ? 45.549 92.355 47.117 1.00 18.71 ? 310 PHE M CA 1 ATOM 2495 C C . PHE A 1 310 ? 45.262 90.822 47.129 1.00 20.46 ? 310 PHE M C 1 ATOM 2496 O O . PHE A 1 310 ? 44.530 90.332 46.257 1.00 21.70 ? 310 PHE M O 1 ATOM 2497 C CB . PHE A 1 310 ? 44.295 93.065 47.650 1.00 18.24 ? 310 PHE M CB 1 ATOM 2498 C CG . PHE A 1 310 ? 44.411 94.539 47.762 1.00 15.01 ? 310 PHE M CG 1 ATOM 2499 C CD1 . PHE A 1 310 ? 45.056 95.063 48.809 1.00 18.46 ? 310 PHE M CD1 1 ATOM 2500 C CD2 . PHE A 1 310 ? 43.943 95.333 46.703 1.00 15.65 ? 310 PHE M CD2 1 ATOM 2501 C CE1 . PHE A 1 310 ? 45.165 96.442 48.971 1.00 16.96 ? 310 PHE M CE1 1 ATOM 2502 C CE2 . PHE A 1 310 ? 44.063 96.752 46.864 1.00 15.12 ? 310 PHE M CE2 1 ATOM 2503 C CZ . PHE A 1 310 ? 44.661 97.249 47.987 1.00 14.84 ? 310 PHE M CZ 1 ATOM 2504 N N . SER A 1 311 ? 45.826 90.113 48.064 1.00 18.13 ? 311 SER M N 1 ATOM 2505 C CA . SER A 1 311 ? 45.359 88.760 48.344 1.00 19.66 ? 311 SER M CA 1 ATOM 2506 C C . SER A 1 311 ? 43.944 88.840 48.880 1.00 21.10 ? 311 SER M C 1 ATOM 2507 O O . SER A 1 311 ? 43.430 89.875 49.333 1.00 18.24 ? 311 SER M O 1 ATOM 2508 C CB . SER A 1 311 ? 46.206 88.107 49.381 1.00 18.36 ? 311 SER M CB 1 ATOM 2509 O OG . SER A 1 311 ? 46.169 88.763 50.640 1.00 19.42 ? 311 SER M OG 1 ATOM 2510 N N . PRO A 1 312 ? 43.235 87.720 48.883 1.00 19.11 ? 312 PRO M N 1 ATOM 2511 C CA . PRO A 1 312 ? 41.949 87.683 49.551 1.00 18.04 ? 312 PRO M CA 1 ATOM 2512 C C . PRO A 1 312 ? 41.964 88.171 51.010 1.00 16.60 ? 312 PRO M C 1 ATOM 2513 O O . PRO A 1 312 ? 41.028 88.964 51.374 1.00 17.50 ? 312 PRO M O 1 ATOM 2514 C CB . PRO A 1 312 ? 41.554 86.179 49.437 1.00 22.21 ? 312 PRO M CB 1 ATOM 2515 C CG . PRO A 1 312 ? 42.248 85.748 48.233 1.00 21.54 ? 312 PRO M CG 1 ATOM 2516 C CD . PRO A 1 312 ? 43.541 86.437 48.145 1.00 22.19 ? 312 PRO M CD 1 ATOM 2517 N N . GLU A 1 313 ? 43.003 87.776 51.749 1.00 16.94 ? 313 GLU M N 1 ATOM 2518 C CA . GLU A 1 313 ? 43.124 88.207 53.136 1.00 17.59 ? 313 GLU M CA 1 ATOM 2519 C C . GLU A 1 313 ? 43.291 89.777 53.192 1.00 16.12 ? 313 GLU M C 1 ATOM 2520 O O . GLU A 1 313 ? 42.657 90.457 54.026 1.00 16.59 ? 313 GLU M O 1 ATOM 2521 C CB . GLU A 1 313 ? 44.322 87.590 53.806 1.00 20.92 ? 313 GLU M CB 1 ATOM 2522 C CG . GLU A 1 313 ? 44.561 87.988 55.226 1.00 31.50 ? 313 GLU M CG 1 ATOM 2523 C CD . GLU A 1 313 ? 45.456 87.001 55.988 1.00 43.06 ? 313 GLU M CD 1 ATOM 2524 O OE1 . GLU A 1 313 ? 45.385 85.783 55.680 1.00 50.70 ? 313 GLU M OE1 1 ATOM 2525 O OE2 . GLU A 1 313 ? 46.202 87.449 56.892 1.00 48.85 ? 313 GLU M OE2 1 ATOM 2526 N N . GLU A 1 314 ? 44.186 90.224 52.358 1.00 16.27 ? 314 GLU M N 1 ATOM 2527 C CA . GLU A 1 314 ? 44.454 91.732 52.294 1.00 15.20 ? 314 GLU M CA 1 ATOM 2528 C C . GLU A 1 314 ? 43.195 92.488 51.884 1.00 14.87 ? 314 GLU M C 1 ATOM 2529 O O . GLU A 1 314 ? 42.882 93.545 52.434 1.00 14.21 ? 314 GLU M O 1 ATOM 2530 C CB . GLU A 1 314 ? 45.587 92.043 51.372 1.00 15.70 ? 314 GLU M CB 1 ATOM 2531 C CG . GLU A 1 314 ? 46.933 91.613 51.945 1.00 17.89 ? 314 GLU M CG 1 ATOM 2532 C CD . GLU A 1 314 ? 48.037 91.634 50.889 1.00 22.04 ? 314 GLU M CD 1 ATOM 2533 O OE1 . GLU A 1 314 ? 47.730 91.675 49.705 1.00 23.12 ? 314 GLU M OE1 1 ATOM 2534 O OE2 . GLU A 1 314 ? 49.216 91.559 51.300 1.00 27.97 ? 314 GLU M OE2 1 ATOM 2535 N N . SER A 1 315 ? 42.464 92.050 50.889 1.00 14.31 ? 315 SER M N 1 ATOM 2536 C CA . SER A 1 315 ? 41.308 92.704 50.413 1.00 13.40 ? 315 SER M CA 1 ATOM 2537 C C . SER A 1 315 ? 40.298 92.796 51.535 1.00 14.90 ? 315 SER M C 1 ATOM 2538 O O . SER A 1 315 ? 39.599 93.795 51.736 1.00 15.26 ? 315 SER M O 1 ATOM 2539 C CB . SER A 1 315 ? 40.780 91.901 49.242 1.00 18.33 ? 315 SER M CB 1 ATOM 2540 O OG . SER A 1 315 ? 39.597 92.465 48.798 1.00 24.76 ? 315 SER M OG 1 ATOM 2541 N N . ASN A 1 316 ? 40.134 91.703 52.305 1.00 13.77 ? 316 ASN M N 1 ATOM 2542 C CA . ASN A 1 316 ? 39.194 91.685 53.411 1.00 15.72 ? 316 ASN M CA 1 ATOM 2543 C C . ASN A 1 316 ? 39.620 92.662 54.548 1.00 13.70 ? 316 ASN M C 1 ATOM 2544 O O . ASN A 1 316 ? 38.760 93.251 55.189 1.00 15.39 ? 316 ASN M O 1 ATOM 2545 C CB . ASN A 1 316 ? 39.008 90.260 53.932 1.00 17.31 ? 316 ASN M CB 1 ATOM 2546 C CG . ASN A 1 316 ? 38.146 90.242 55.099 1.00 22.94 ? 316 ASN M CG 1 ATOM 2547 O OD1 . ASN A 1 316 ? 36.914 90.339 54.948 1.00 31.60 ? 316 ASN M OD1 1 ATOM 2548 N ND2 . ASN A 1 316 ? 38.735 90.116 56.277 1.00 23.93 ? 316 ASN M ND2 1 ATOM 2549 N N . LEU A 1 317 ? 40.912 92.740 54.754 1.00 13.01 ? 317 LEU M N 1 ATOM 2550 C CA . LEU A 1 317 ? 41.444 93.656 55.760 1.00 12.58 ? 317 LEU M CA 1 ATOM 2551 C C . LEU A 1 317 ? 41.156 95.141 55.393 1.00 9.94 ? 317 LEU M C 1 ATOM 2552 O O . LEU A 1 317 ? 40.764 95.948 56.272 1.00 11.72 ? 317 LEU M O 1 ATOM 2553 C CB . LEU A 1 317 ? 42.919 93.480 55.950 1.00 13.90 ? 317 LEU M CB 1 ATOM 2554 C CG . LEU A 1 317 ? 43.675 94.279 57.051 1.00 17.15 ? 317 LEU M CG 1 ATOM 2555 C CD1 . LEU A 1 317 ? 43.231 93.766 58.336 1.00 23.03 ? 317 LEU M CD1 1 ATOM 2556 C CD2 . LEU A 1 317 ? 45.230 94.241 56.850 1.00 25.47 ? 317 LEU M CD2 1 ATOM 2557 N N . VAL A 1 318 ? 41.366 95.451 54.137 1.00 11.19 ? 318 VAL M N 1 ATOM 2558 C CA . VAL A 1 318 ? 41.254 96.856 53.685 1.00 9.72 ? 318 VAL M CA 1 ATOM 2559 C C . VAL A 1 318 ? 39.836 97.308 53.443 1.00 9.20 ? 318 VAL M C 1 ATOM 2560 O O . VAL A 1 318 ? 39.428 98.423 53.789 1.00 9.02 ? 318 VAL M O 1 ATOM 2561 C CB . VAL A 1 318 ? 42.110 97.083 52.404 1.00 10.93 ? 318 VAL M CB 1 ATOM 2562 C CG1 . VAL A 1 318 ? 41.926 98.529 51.912 1.00 13.41 ? 318 VAL M CG1 1 ATOM 2563 C CG2 . VAL A 1 318 ? 43.562 96.819 52.626 1.00 13.18 ? 318 VAL M CG2 1 ATOM 2564 N N . LYS A 1 319 ? 38.977 96.378 52.931 1.00 9.30 ? 319 LYS M N 1 ATOM 2565 C CA . LYS A 1 319 ? 37.607 96.684 52.732 1.00 9.52 ? 319 LYS M CA 1 ATOM 2566 C C . LYS A 1 319 ? 36.867 97.024 53.999 1.00 9.74 ? 319 LYS M C 1 ATOM 2567 O O . LYS A 1 319 ? 36.872 96.261 54.972 1.00 12.62 ? 319 LYS M O 1 ATOM 2568 C CB . LYS A 1 319 ? 36.847 95.499 52.009 1.00 10.41 ? 319 LYS M CB 1 ATOM 2569 C CG . LYS A 1 319 ? 35.430 95.877 51.676 1.00 11.37 ? 319 LYS M CG 1 ATOM 2570 C CD . LYS A 1 319 ? 34.725 94.633 50.965 1.00 14.66 ? 319 LYS M CD 1 ATOM 2571 C CE . LYS A 1 319 ? 33.241 94.889 50.864 1.00 23.29 ? 319 LYS M CE 1 ATOM 2572 N NZ . LYS A 1 319 ? 32.594 93.620 50.370 1.00 27.37 ? 319 LYS M NZ 1 ATOM 2573 N N . GLY A 1 320 ? 36.283 98.180 54.053 1.00 9.48 ? 320 GLY M N 1 ATOM 2574 C CA . GLY A 1 320 ? 35.507 98.599 55.193 1.00 9.74 ? 320 GLY M CA 1 ATOM 2575 C C . GLY A 1 320 ? 36.342 99.082 56.414 1.00 10.19 ? 320 GLY M C 1 ATOM 2576 O O . GLY A 1 320 ? 35.791 99.260 57.520 1.00 9.35 ? 320 GLY M O 1 ATOM 2577 N N . SER A 1 321 ? 37.623 99.423 56.165 1.00 9.76 ? 321 SER M N 1 ATOM 2578 C CA . SER A 1 321 ? 38.578 99.755 57.207 1.00 8.78 ? 321 SER M CA 1 ATOM 2579 C C . SER A 1 321 ? 38.446 101.205 57.653 1.00 8.40 ? 321 SER M C 1 ATOM 2580 O O . SER A 1 321 ? 39.466 101.948 57.637 1.00 8.22 ? 321 SER M O 1 ATOM 2581 C CB . SER A 1 321 ? 40.044 99.408 56.813 1.00 10.74 ? 321 SER M CB 1 ATOM 2582 O OG . SER A 1 321 ? 40.426 100.065 55.615 1.00 10.29 ? 321 SER M OG 1 ATOM 2583 N N . TYR A 1 322 ? 37.275 101.625 58.039 1.00 8.85 ? 322 TYR M N 1 ATOM 2584 C CA . TYR A 1 322 ? 37.052 102.980 58.541 1.00 7.58 ? 322 TYR M CA 1 ATOM 2585 C C . TYR A 1 322 ? 35.761 103.056 59.241 1.00 10.08 ? 322 TYR M C 1 ATOM 2586 O O . TYR A 1 322 ? 34.826 102.311 58.911 1.00 10.12 ? 322 TYR M O 1 ATOM 2587 C CB . TYR A 1 322 ? 37.119 103.991 57.401 1.00 7.15 ? 322 TYR M CB 1 ATOM 2588 C CG . TYR A 1 322 ? 36.056 103.780 56.299 1.00 8.70 ? 322 TYR M CG 1 ATOM 2589 C CD1 . TYR A 1 322 ? 36.214 102.877 55.281 1.00 12.71 ? 322 TYR M CD1 1 ATOM 2590 C CD2 . TYR A 1 322 ? 34.834 104.443 56.422 1.00 9.15 ? 322 TYR M CD2 1 ATOM 2591 C CE1 . TYR A 1 322 ? 35.209 102.675 54.332 1.00 14.38 ? 322 TYR M CE1 1 ATOM 2592 C CE2 . TYR A 1 322 ? 33.826 104.272 55.461 1.00 12.88 ? 322 TYR M CE2 1 ATOM 2593 C CZ . TYR A 1 322 ? 34.024 103.404 54.412 1.00 16.87 ? 322 TYR M CZ 1 ATOM 2594 O OH . TYR A 1 322 ? 33.005 103.110 53.467 1.00 15.61 ? 322 TYR M OH 1 ATOM 2595 N N . ASP A 1 323 ? 35.732 103.822 60.304 1.00 9.14 ? 323 ASP M N 1 ATOM 2596 C CA . ASP A 1 323 ? 34.528 104.229 60.978 1.00 9.51 ? 323 ASP M CA 1 ATOM 2597 C C . ASP A 1 323 ? 33.957 105.523 60.405 1.00 10.25 ? 323 ASP M C 1 ATOM 2598 O O . ASP A 1 323 ? 32.756 105.853 60.517 1.00 10.98 ? 323 ASP M O 1 ATOM 2599 C CB . ASP A 1 323 ? 34.780 104.453 62.438 1.00 9.21 ? 323 ASP M CB 1 ATOM 2600 C CG . ASP A 1 323 ? 35.233 103.248 63.172 1.00 12.16 ? 323 ASP M CG 1 ATOM 2601 O OD1 . ASP A 1 323 ? 34.633 102.098 62.866 1.00 13.71 ? 323 ASP M OD1 1 ATOM 2602 O OD2 . ASP A 1 323 ? 36.146 103.244 63.988 1.00 11.63 ? 323 ASP M OD2 1 ATOM 2603 N N . PHE A 1 324 ? 34.848 106.375 59.823 1.00 10.10 ? 324 PHE M N 1 ATOM 2604 C CA . PHE A 1 324 ? 34.512 107.633 59.217 1.00 9.61 ? 324 PHE M CA 1 ATOM 2605 C C . PHE A 1 324 ? 35.623 107.964 58.288 1.00 8.34 ? 324 PHE M C 1 ATOM 2606 O O . PHE A 1 324 ? 36.716 107.306 58.313 1.00 8.06 ? 324 PHE M O 1 ATOM 2607 C CB . PHE A 1 324 ? 34.382 108.743 60.291 1.00 7.56 ? 324 PHE M CB 1 ATOM 2608 C CG . PHE A 1 324 ? 35.631 109.122 61.002 1.00 8.55 ? 324 PHE M CG 1 ATOM 2609 C CD1 . PHE A 1 324 ? 36.051 108.507 62.097 1.00 10.81 ? 324 PHE M CD1 1 ATOM 2610 C CD2 . PHE A 1 324 ? 36.383 110.157 60.484 1.00 12.79 ? 324 PHE M CD2 1 ATOM 2611 C CE1 . PHE A 1 324 ? 37.235 108.899 62.759 1.00 11.85 ? 324 PHE M CE1 1 ATOM 2612 C CE2 . PHE A 1 324 ? 37.546 110.533 61.183 1.00 14.67 ? 324 PHE M CE2 1 ATOM 2613 C CZ . PHE A 1 324 ? 37.952 109.852 62.281 1.00 12.75 ? 324 PHE M CZ 1 ATOM 2614 N N . LEU A 1 325 ? 35.401 108.989 57.451 1.00 8.04 ? 325 LEU M N 1 ATOM 2615 C CA . LEU A 1 325 ? 36.430 109.477 56.551 1.00 8.41 ? 325 LEU M CA 1 ATOM 2616 C C . LEU A 1 325 ? 36.756 110.883 56.936 1.00 8.59 ? 325 LEU M C 1 ATOM 2617 O O . LEU A 1 325 ? 35.873 111.683 57.135 1.00 9.10 ? 325 LEU M O 1 ATOM 2618 C CB . LEU A 1 325 ? 35.947 109.449 55.124 1.00 9.51 ? 325 LEU M CB 1 ATOM 2619 C CG . LEU A 1 325 ? 35.482 108.136 54.547 1.00 10.23 ? 325 LEU M CG 1 ATOM 2620 C CD1 . LEU A 1 325 ? 34.770 108.287 53.187 1.00 10.97 ? 325 LEU M CD1 1 ATOM 2621 C CD2 . LEU A 1 325 ? 36.657 107.150 54.496 1.00 10.98 ? 325 LEU M CD2 1 ATOM 2622 N N . GLY A 1 326 ? 38.032 111.193 57.013 1.00 8.61 ? 326 GLY M N 1 ATOM 2623 C CA . GLY A 1 326 ? 38.414 112.593 57.132 1.00 8.82 ? 326 GLY M CA 1 ATOM 2624 C C . GLY A 1 326 ? 38.683 113.068 55.712 1.00 8.67 ? 326 GLY M C 1 ATOM 2625 O O . GLY A 1 326 ? 39.562 112.563 55.029 1.00 9.62 ? 326 GLY M O 1 ATOM 2626 N N . LEU A 1 327 ? 37.895 114.010 55.255 1.00 7.02 ? 327 LEU M N 1 ATOM 2627 C CA . LEU A 1 327 ? 38.001 114.597 53.925 1.00 7.05 ? 327 LEU M CA 1 ATOM 2628 C C . LEU A 1 327 ? 38.600 115.981 53.961 1.00 7.80 ? 327 LEU M C 1 ATOM 2629 O O . LEU A 1 327 ? 38.036 116.875 54.621 1.00 8.75 ? 327 LEU M O 1 ATOM 2630 C CB . LEU A 1 327 ? 36.661 114.524 53.202 1.00 7.34 ? 327 LEU M CB 1 ATOM 2631 C CG . LEU A 1 327 ? 35.973 113.146 53.035 1.00 9.64 ? 327 LEU M CG 1 ATOM 2632 C CD1 . LEU A 1 327 ? 34.722 113.366 52.126 1.00 12.01 ? 327 LEU M CD1 1 ATOM 2633 C CD2 . LEU A 1 327 ? 37.014 112.149 52.566 1.00 8.36 ? 327 LEU M CD2 1 ATOM 2634 N N . ASN A 1 328 ? 39.753 116.120 53.359 1.00 8.00 ? 328 ASN M N 1 ATOM 2635 C CA . ASN A 1 328 ? 40.335 117.464 53.114 1.00 7.32 ? 328 ASN M CA 1 ATOM 2636 C C . ASN A 1 328 ? 39.856 117.940 51.795 1.00 7.28 ? 328 ASN M C 1 ATOM 2637 O O . ASN A 1 328 ? 39.839 117.168 50.821 1.00 8.02 ? 328 ASN M O 1 ATOM 2638 C CB . ASN A 1 328 ? 41.864 117.353 53.115 1.00 7.37 ? 328 ASN M CB 1 ATOM 2639 C CG . ASN A 1 328 ? 42.463 116.922 54.442 1.00 9.64 ? 328 ASN M CG 1 ATOM 2640 O OD1 . ASN A 1 328 ? 41.785 116.796 55.435 1.00 8.20 ? 328 ASN M OD1 1 ATOM 2641 N ND2 . ASN A 1 328 ? 43.814 116.784 54.480 1.00 9.49 ? 328 ASN M ND2 1 ATOM 2642 N N . TYR A 1 329 ? 39.558 119.199 51.649 1.00 7.59 ? 329 TYR M N 1 ATOM 2643 C CA . TYR A 1 329 ? 39.078 119.769 50.402 1.00 6.83 ? 329 TYR M CA 1 ATOM 2644 C C . TYR A 1 329 ? 39.607 121.199 50.264 1.00 8.44 ? 329 TYR M C 1 ATOM 2645 O O . TYR A 1 329 ? 39.478 121.986 51.177 1.00 6.60 ? 329 TYR M O 1 ATOM 2646 C CB . TYR A 1 329 ? 37.568 119.798 50.284 1.00 6.91 ? 329 TYR M CB 1 ATOM 2647 C CG . TYR A 1 329 ? 37.147 120.505 49.023 1.00 7.11 ? 329 TYR M CG 1 ATOM 2648 C CD1 . TYR A 1 329 ? 37.174 119.864 47.784 1.00 7.60 ? 329 TYR M CD1 1 ATOM 2649 C CD2 . TYR A 1 329 ? 36.766 121.844 49.038 1.00 8.38 ? 329 TYR M CD2 1 ATOM 2650 C CE1 . TYR A 1 329 ? 36.919 120.555 46.601 1.00 7.46 ? 329 TYR M CE1 1 ATOM 2651 C CE2 . TYR A 1 329 ? 36.571 122.556 47.895 1.00 7.32 ? 329 TYR M CE2 1 ATOM 2652 C CZ . TYR A 1 329 ? 36.589 121.878 46.660 1.00 6.55 ? 329 TYR M CZ 1 ATOM 2653 O OH . TYR A 1 329 ? 36.431 122.618 45.471 1.00 7.52 ? 329 TYR M OH 1 ATOM 2654 N N . TYR A 1 330 ? 40.269 121.455 49.143 1.00 8.76 ? 330 TYR M N 1 ATOM 2655 C CA . TYR A 1 330 ? 40.720 122.809 48.770 1.00 8.36 ? 330 TYR M CA 1 ATOM 2656 C C . TYR A 1 330 ? 40.194 123.361 47.458 1.00 8.74 ? 330 TYR M C 1 ATOM 2657 O O . TYR A 1 330 ? 39.798 124.545 47.457 1.00 9.38 ? 330 TYR M O 1 ATOM 2658 C CB . TYR A 1 330 ? 42.245 122.824 48.805 1.00 7.27 ? 330 TYR M CB 1 ATOM 2659 C CG . TYR A 1 330 ? 42.839 122.614 50.158 1.00 8.28 ? 330 TYR M CG 1 ATOM 2660 C CD1 . TYR A 1 330 ? 43.056 123.688 51.039 1.00 8.66 ? 330 TYR M CD1 1 ATOM 2661 C CD2 . TYR A 1 330 ? 43.190 121.322 50.584 1.00 11.52 ? 330 TYR M CD2 1 ATOM 2662 C CE1 . TYR A 1 330 ? 43.601 123.472 52.251 1.00 9.91 ? 330 TYR M CE1 1 ATOM 2663 C CE2 . TYR A 1 330 ? 43.758 121.139 51.866 1.00 10.68 ? 330 TYR M CE2 1 ATOM 2664 C CZ . TYR A 1 330 ? 43.975 122.257 52.662 1.00 9.26 ? 330 TYR M CZ 1 ATOM 2665 O OH . TYR A 1 330 ? 44.568 122.178 53.935 1.00 12.46 ? 330 TYR M OH 1 ATOM 2666 N N . PHE A 1 331 ? 40.169 122.554 46.405 1.00 7.59 ? 331 PHE M N 1 ATOM 2667 C CA . PHE A 1 331 ? 39.844 123.121 45.090 1.00 8.21 ? 331 PHE M CA 1 ATOM 2668 C C . PHE A 1 331 ? 39.421 121.999 44.102 1.00 8.13 ? 331 PHE M C 1 ATOM 2669 O O . PHE A 1 331 ? 39.446 120.791 44.401 1.00 8.65 ? 331 PHE M O 1 ATOM 2670 C CB . PHE A 1 331 ? 41.011 123.967 44.516 1.00 8.49 ? 331 PHE M CB 1 ATOM 2671 C CG . PHE A 1 331 ? 42.322 123.254 44.436 1.00 8.19 ? 331 PHE M CG 1 ATOM 2672 C CD1 . PHE A 1 331 ? 42.577 122.335 43.458 1.00 12.14 ? 331 PHE M CD1 1 ATOM 2673 C CD2 . PHE A 1 331 ? 43.383 123.617 45.266 1.00 13.52 ? 331 PHE M CD2 1 ATOM 2674 C CE1 . PHE A 1 331 ? 43.830 121.704 43.330 1.00 14.01 ? 331 PHE M CE1 1 ATOM 2675 C CE2 . PHE A 1 331 ? 44.595 122.973 45.149 1.00 13.84 ? 331 PHE M CE2 1 ATOM 2676 C CZ . PHE A 1 331 ? 44.791 122.017 44.200 1.00 13.66 ? 331 PHE M CZ 1 ATOM 2677 N N . THR A 1 332 ? 38.994 122.482 42.946 1.00 6.60 ? 332 THR M N 1 ATOM 2678 C CA . THR A 1 332 ? 38.434 121.677 41.842 1.00 6.69 ? 332 THR M CA 1 ATOM 2679 C C . THR A 1 332 ? 39.160 122.061 40.547 1.00 8.43 ? 332 THR M C 1 ATOM 2680 O O . THR A 1 332 ? 39.557 123.190 40.314 1.00 8.94 ? 332 THR M O 1 ATOM 2681 C CB . THR A 1 332 ? 36.971 122.001 41.714 1.00 8.90 ? 332 THR M CB 1 ATOM 2682 O OG1 . THR A 1 332 ? 36.262 121.522 42.873 1.00 9.14 ? 332 THR M OG1 1 ATOM 2683 C CG2 . THR A 1 332 ? 36.221 121.422 40.451 1.00 8.52 ? 332 THR M CG2 1 ATOM 2684 N N . GLN A 1 333 ? 39.287 121.049 39.676 1.00 6.85 ? 333 GLN M N 1 ATOM 2685 C CA . GLN A 1 333 ? 39.989 121.245 38.402 1.00 7.85 ? 333 GLN M CA 1 ATOM 2686 C C . GLN A 1 333 ? 39.111 120.811 37.225 1.00 7.89 ? 333 GLN M C 1 ATOM 2687 O O . GLN A 1 333 ? 38.266 119.911 37.338 1.00 8.85 ? 333 GLN M O 1 ATOM 2688 C CB . GLN A 1 333 ? 41.271 120.503 38.339 1.00 9.93 ? 333 GLN M CB 1 ATOM 2689 C CG . GLN A 1 333 ? 42.381 121.057 39.236 1.00 10.73 ? 333 GLN M CG 1 ATOM 2690 C CD . GLN A 1 333 ? 43.405 120.042 39.686 1.00 10.65 ? 333 GLN M CD 1 ATOM 2691 O OE1 . GLN A 1 333 ? 43.131 118.938 39.990 1.00 14.16 ? 333 GLN M OE1 1 ATOM 2692 N NE2 . GLN A 1 333 ? 44.722 120.437 39.541 1.00 15.90 ? 333 GLN M NE2 1 ATOM 2693 N N . TYR A 1 334 ? 39.362 121.472 36.104 1.00 7.63 ? 334 TYR M N 1 ATOM 2694 C CA . TYR A 1 334 ? 38.845 120.994 34.841 1.00 8.12 ? 334 TYR M CA 1 ATOM 2695 C C . TYR A 1 334 ? 39.768 119.934 34.306 1.00 8.32 ? 334 TYR M C 1 ATOM 2696 O O . TYR A 1 334 ? 41.000 120.005 34.397 1.00 8.66 ? 334 TYR M O 1 ATOM 2697 C CB . TYR A 1 334 ? 38.795 122.134 33.793 1.00 7.00 ? 334 TYR M CB 1 ATOM 2698 C CG . TYR A 1 334 ? 37.762 123.202 34.067 1.00 5.83 ? 334 TYR M CG 1 ATOM 2699 C CD1 . TYR A 1 334 ? 36.400 122.937 34.101 1.00 9.33 ? 334 TYR M CD1 1 ATOM 2700 C CD2 . TYR A 1 334 ? 38.142 124.491 34.431 1.00 7.95 ? 334 TYR M CD2 1 ATOM 2701 C CE1 . TYR A 1 334 ? 35.467 123.868 34.429 1.00 9.43 ? 334 TYR M CE1 1 ATOM 2702 C CE2 . TYR A 1 334 ? 37.206 125.398 34.656 1.00 7.81 ? 334 TYR M CE2 1 ATOM 2703 C CZ . TYR A 1 334 ? 35.864 125.165 34.691 1.00 9.17 ? 334 TYR M CZ 1 ATOM 2704 O OH . TYR A 1 334 ? 34.897 126.130 34.994 1.00 11.57 ? 334 TYR M OH 1 ATOM 2705 N N . ALA A 1 335 ? 39.202 118.913 33.630 1.00 6.73 ? 335 ALA M N 1 ATOM 2706 C CA . ALA A 1 335 ? 39.905 117.859 33.024 1.00 7.91 ? 335 ALA M CA 1 ATOM 2707 C C . ALA A 1 335 ? 39.684 117.703 31.544 1.00 9.22 ? 335 ALA M C 1 ATOM 2708 O O . ALA A 1 335 ? 38.547 117.808 31.105 1.00 8.49 ? 335 ALA M O 1 ATOM 2709 C CB . ALA A 1 335 ? 39.540 116.449 33.751 1.00 7.49 ? 335 ALA M CB 1 ATOM 2710 N N . GLN A 1 336 ? 40.807 117.465 30.837 1.00 9.87 ? 336 GLN M N 1 ATOM 2711 C CA . GLN A 1 336 ? 40.805 117.210 29.402 1.00 9.76 ? 336 GLN M CA 1 ATOM 2712 C C . GLN A 1 336 ? 41.668 116.038 29.136 1.00 10.38 ? 336 GLN M C 1 ATOM 2713 O O . GLN A 1 336 ? 42.526 115.644 29.912 1.00 9.86 ? 336 GLN M O 1 ATOM 2714 C CB . GLN A 1 336 ? 41.232 118.427 28.590 1.00 11.28 ? 336 GLN M CB 1 ATOM 2715 C CG . GLN A 1 336 ? 42.655 118.763 28.850 1.00 10.63 ? 336 GLN M CG 1 ATOM 2716 C CD . GLN A 1 336 ? 43.064 120.073 28.222 1.00 13.86 ? 336 GLN M CD 1 ATOM 2717 O OE1 . GLN A 1 336 ? 43.019 121.143 28.926 1.00 14.85 ? 336 GLN M OE1 1 ATOM 2718 N NE2 . GLN A 1 336 ? 43.441 120.084 26.982 1.00 12.48 ? 336 GLN M NE2 1 ATOM 2719 N N . PRO A 1 337 ? 41.519 115.409 27.958 1.00 8.94 ? 337 PRO M N 1 ATOM 2720 C CA . PRO A 1 337 ? 42.419 114.287 27.704 1.00 9.94 ? 337 PRO M CA 1 ATOM 2721 C C . PRO A 1 337 ? 43.883 114.656 27.517 1.00 11.98 ? 337 PRO M C 1 ATOM 2722 O O . PRO A 1 337 ? 44.228 115.750 27.116 1.00 13.68 ? 337 PRO M O 1 ATOM 2723 C CB . PRO A 1 337 ? 41.852 113.637 26.426 1.00 14.10 ? 337 PRO M CB 1 ATOM 2724 C CG . PRO A 1 337 ? 40.956 114.604 25.921 1.00 13.96 ? 337 PRO M CG 1 ATOM 2725 C CD . PRO A 1 337 ? 40.562 115.648 26.876 1.00 11.68 ? 337 PRO M CD 1 ATOM 2726 N N . SER A 1 338 ? 44.704 113.692 27.869 1.00 12.15 ? 338 SER M N 1 ATOM 2727 C CA . SER A 1 338 ? 46.173 113.766 27.700 1.00 13.68 ? 338 SER M CA 1 ATOM 2728 C C . SER A 1 338 ? 46.706 112.388 27.438 1.00 14.58 ? 338 SER M C 1 ATOM 2729 O O . SER A 1 338 ? 46.237 111.403 27.993 1.00 12.03 ? 338 SER M O 1 ATOM 2730 C CB A SER A 1 338 ? 46.774 114.287 29.001 0.70 15.23 ? 338 SER M CB 1 ATOM 2731 C CB B SER A 1 338 ? 46.845 114.449 28.866 0.30 14.92 ? 338 SER M CB 1 ATOM 2732 O OG A SER A 1 338 ? 48.178 114.473 28.919 0.70 17.82 ? 338 SER M OG 1 ATOM 2733 O OG B SER A 1 338 ? 46.681 113.666 29.997 0.30 16.19 ? 338 SER M OG 1 ATOM 2734 N N . PRO A 1 339 ? 47.697 112.282 26.600 1.00 17.06 ? 339 PRO M N 1 ATOM 2735 C CA . PRO A 1 339 ? 48.345 111.007 26.325 1.00 17.61 ? 339 PRO M CA 1 ATOM 2736 C C . PRO A 1 339 ? 49.008 110.422 27.549 1.00 14.72 ? 339 PRO M C 1 ATOM 2737 O O . PRO A 1 339 ? 49.416 111.133 28.469 1.00 17.08 ? 339 PRO M O 1 ATOM 2738 C CB . PRO A 1 339 ? 49.467 111.402 25.319 1.00 19.66 ? 339 PRO M CB 1 ATOM 2739 C CG . PRO A 1 339 ? 49.259 112.731 24.941 1.00 23.36 ? 339 PRO M CG 1 ATOM 2740 C CD . PRO A 1 339 ? 48.329 113.417 25.894 1.00 20.17 ? 339 PRO M CD 1 ATOM 2741 N N . ASN A 1 340 ? 49.134 109.072 27.524 1.00 14.77 ? 340 ASN M N 1 ATOM 2742 C CA . ASN A 1 340 ? 49.867 108.405 28.603 1.00 14.19 ? 340 ASN M CA 1 ATOM 2743 C C . ASN A 1 340 ? 51.043 107.566 27.994 1.00 15.99 ? 340 ASN M C 1 ATOM 2744 O O . ASN A 1 340 ? 50.821 106.382 27.658 1.00 19.33 ? 340 ASN M O 1 ATOM 2745 C CB . ASN A 1 340 ? 48.937 107.444 29.284 1.00 13.80 ? 340 ASN M CB 1 ATOM 2746 C CG . ASN A 1 340 ? 49.591 106.672 30.414 1.00 13.04 ? 340 ASN M CG 1 ATOM 2747 O OD1 . ASN A 1 340 ? 50.515 107.264 31.016 1.00 15.17 ? 340 ASN M OD1 1 ATOM 2748 N ND2 . ASN A 1 340 ? 49.049 105.538 30.827 1.00 12.69 ? 340 ASN M ND2 1 ATOM 2749 N N . PRO A 1 341 ? 52.197 108.185 27.937 1.00 18.59 ? 341 PRO M N 1 ATOM 2750 C CA . PRO A 1 341 ? 53.334 107.516 27.256 1.00 20.57 ? 341 PRO M CA 1 ATOM 2751 C C . PRO A 1 341 ? 54.112 106.675 28.231 1.00 18.72 ? 341 PRO M C 1 ATOM 2752 O O . PRO A 1 341 ? 55.204 107.082 28.727 1.00 18.44 ? 341 PRO M O 1 ATOM 2753 C CB . PRO A 1 341 ? 54.143 108.681 26.772 1.00 21.43 ? 341 PRO M CB 1 ATOM 2754 C CG . PRO A 1 341 ? 53.981 109.814 27.800 1.00 26.19 ? 341 PRO M CG 1 ATOM 2755 C CD . PRO A 1 341 ? 52.564 109.560 28.419 1.00 22.88 ? 341 PRO M CD 1 ATOM 2756 N N . VAL A 1 342 ? 53.620 105.495 28.430 1.00 18.35 ? 342 VAL M N 1 ATOM 2757 C CA . VAL A 1 342 ? 54.104 104.545 29.441 1.00 19.72 ? 342 VAL M CA 1 ATOM 2758 C C . VAL A 1 342 ? 55.593 104.141 29.215 1.00 22.71 ? 342 VAL M C 1 ATOM 2759 O O . VAL A 1 342 ? 56.308 103.889 30.183 1.00 22.17 ? 342 VAL M O 1 ATOM 2760 C CB A VAL A 1 342 ? 53.187 103.344 29.574 0.50 19.21 ? 342 VAL M CB 1 ATOM 2761 C CB B VAL A 1 342 ? 53.327 103.283 29.445 0.50 19.25 ? 342 VAL M CB 1 ATOM 2762 C CG1 A VAL A 1 342 ? 53.659 102.343 30.639 0.50 19.01 ? 342 VAL M CG1 1 ATOM 2763 C CG1 B VAL A 1 342 ? 51.880 103.464 30.068 0.50 18.83 ? 342 VAL M CG1 1 ATOM 2764 C CG2 A VAL A 1 342 ? 51.757 103.824 29.930 0.50 19.40 ? 342 VAL M CG2 1 ATOM 2765 C CG2 B VAL A 1 342 ? 53.279 102.749 27.999 0.50 18.37 ? 342 VAL M CG2 1 ATOM 2766 N N . ASN A 1 343 ? 56.054 104.206 27.972 1.00 24.60 ? 343 ASN M N 1 ATOM 2767 C CA . ASN A 1 343 ? 57.473 103.959 27.683 1.00 26.66 ? 343 ASN M CA 1 ATOM 2768 C C . ASN A 1 343 ? 58.424 105.103 27.798 1.00 26.08 ? 343 ASN M C 1 ATOM 2769 O O . ASN A 1 343 ? 59.629 104.865 27.598 1.00 29.42 ? 343 ASN M O 1 ATOM 2770 C CB . ASN A 1 343 ? 57.600 103.461 26.209 1.00 29.92 ? 343 ASN M CB 1 ATOM 2771 C CG . ASN A 1 343 ? 56.804 102.244 25.975 1.00 31.07 ? 343 ASN M CG 1 ATOM 2772 O OD1 . ASN A 1 343 ? 56.687 101.386 26.860 1.00 39.31 ? 343 ASN M OD1 1 ATOM 2773 N ND2 . ASN A 1 343 ? 56.267 102.121 24.748 1.00 38.06 ? 343 ASN M ND2 1 ATOM 2774 N N . SER A 1 344 ? 57.974 106.318 28.000 1.00 21.65 ? 344 SER M N 1 ATOM 2775 C CA . SER A 1 344 ? 58.832 107.515 28.094 1.00 23.32 ? 344 SER M CA 1 ATOM 2776 C C . SER A 1 344 ? 59.647 107.344 29.415 1.00 22.73 ? 344 SER M C 1 ATOM 2777 O O . SER A 1 344 ? 59.111 106.796 30.421 1.00 19.49 ? 344 SER M O 1 ATOM 2778 C CB A SER A 1 344 ? 58.050 108.804 28.096 0.50 24.13 ? 344 SER M CB 1 ATOM 2779 C CB B SER A 1 344 ? 57.995 108.724 28.178 0.50 23.98 ? 344 SER M CB 1 ATOM 2780 O OG A SER A 1 344 ? 57.662 109.275 26.776 0.50 28.93 ? 344 SER M OG 1 ATOM 2781 O OG B SER A 1 344 ? 58.759 109.884 28.431 0.50 30.12 ? 344 SER M OG 1 ATOM 2782 N N . THR A 1 345 ? 60.924 107.631 29.344 1.00 22.06 ? 345 THR M N 1 ATOM 2783 C CA . THR A 1 345 ? 61.753 107.458 30.535 1.00 21.61 ? 345 THR M CA 1 ATOM 2784 C C . THR A 1 345 ? 61.203 108.467 31.595 1.00 20.75 ? 345 THR M C 1 ATOM 2785 O O . THR A 1 345 ? 61.483 108.218 32.802 1.00 20.06 ? 345 THR M O 1 ATOM 2786 C CB . THR A 1 345 ? 63.278 107.741 30.245 1.00 21.77 ? 345 THR M CB 1 ATOM 2787 O OG1 . THR A 1 345 ? 63.404 109.113 29.942 1.00 30.18 ? 345 THR M OG1 1 ATOM 2788 C CG2 . THR A 1 345 ? 63.851 106.775 29.203 1.00 30.87 ? 345 THR M CG2 1 ATOM 2789 N N . ASN A 1 346 ? 60.521 109.560 31.222 1.00 17.19 ? 346 ASN M N 1 ATOM 2790 C CA . ASN A 1 346 ? 59.940 110.432 32.196 1.00 19.48 ? 346 ASN M CA 1 ATOM 2791 C C . ASN A 1 346 ? 58.439 110.160 32.559 1.00 14.95 ? 346 ASN M C 1 ATOM 2792 O O . ASN A 1 346 ? 57.819 110.985 33.209 1.00 17.22 ? 346 ASN M O 1 ATOM 2793 C CB . ASN A 1 346 ? 60.206 111.843 31.870 1.00 23.14 ? 346 ASN M CB 1 ATOM 2794 C CG . ASN A 1 346 ? 59.375 112.327 30.830 1.00 27.24 ? 346 ASN M CG 1 ATOM 2795 O OD1 . ASN A 1 346 ? 58.401 111.647 30.385 1.00 29.29 ? 346 ASN M OD1 1 ATOM 2796 N ND2 . ASN A 1 346 ? 59.704 113.570 30.394 1.00 35.91 ? 346 ASN M ND2 1 ATOM 2797 N N . HIS A 1 347 ? 58.029 108.938 32.275 1.00 15.02 ? 347 HIS M N 1 ATOM 2798 C CA . HIS A 1 347 ? 56.659 108.504 32.619 1.00 13.21 ? 347 HIS M CA 1 ATOM 2799 C C . HIS A 1 347 ? 56.459 108.595 34.158 1.00 13.45 ? 347 HIS M C 1 ATOM 2800 O O . HIS A 1 347 ? 57.322 108.109 34.935 1.00 14.05 ? 347 HIS M O 1 ATOM 2801 C CB . HIS A 1 347 ? 56.330 107.137 32.168 1.00 13.72 ? 347 HIS M CB 1 ATOM 2802 C CG . HIS A 1 347 ? 54.883 106.780 32.410 1.00 11.37 ? 347 HIS M CG 1 ATOM 2803 N ND1 . HIS A 1 347 ? 54.478 105.881 33.365 1.00 13.48 ? 347 HIS M ND1 1 ATOM 2804 C CD2 . HIS A 1 347 ? 53.754 107.207 31.796 1.00 12.10 ? 347 HIS M CD2 1 ATOM 2805 C CE1 . HIS A 1 347 ? 53.144 105.787 33.327 1.00 13.06 ? 347 HIS M CE1 1 ATOM 2806 N NE2 . HIS A 1 347 ? 52.694 106.581 32.376 1.00 12.91 ? 347 HIS M NE2 1 ATOM 2807 N N . THR A 1 348 ? 55.315 109.122 34.557 1.00 11.80 ? 348 THR M N 1 ATOM 2808 C CA . THR A 1 348 ? 54.937 109.076 35.968 1.00 11.34 ? 348 THR M CA 1 ATOM 2809 C C . THR A 1 348 ? 53.641 108.404 36.147 1.00 12.56 ? 348 THR M C 1 ATOM 2810 O O . THR A 1 348 ? 52.798 108.365 35.228 1.00 11.36 ? 348 THR M O 1 ATOM 2811 C CB . THR A 1 348 ? 54.831 110.477 36.558 1.00 12.25 ? 348 THR M CB 1 ATOM 2812 O OG1 . THR A 1 348 ? 53.691 111.177 35.999 1.00 12.79 ? 348 THR M OG1 1 ATOM 2813 C CG2 . THR A 1 348 ? 56.104 111.374 36.348 1.00 13.42 ? 348 THR M CG2 1 ATOM 2814 N N . ALA A 1 349 ? 53.353 107.911 37.316 1.00 10.89 ? 349 ALA M N 1 ATOM 2815 C CA . ALA A 1 349 ? 52.062 107.356 37.629 1.00 10.67 ? 349 ALA M CA 1 ATOM 2816 C C . ALA A 1 349 ? 50.927 108.290 37.378 1.00 9.47 ? 349 ALA M C 1 ATOM 2817 O O . ALA A 1 349 ? 49.819 107.849 37.009 1.00 11.21 ? 349 ALA M O 1 ATOM 2818 C CB . ALA A 1 349 ? 52.098 106.834 39.087 1.00 10.73 ? 349 ALA M CB 1 ATOM 2819 N N . MET A 1 350 ? 51.114 109.563 37.592 1.00 9.65 ? 350 MET M N 1 ATOM 2820 C CA . MET A 1 350 ? 50.108 110.627 37.442 1.00 12.27 ? 350 MET M CA 1 ATOM 2821 C C . MET A 1 350 ? 49.656 110.741 35.974 1.00 12.72 ? 350 MET M C 1 ATOM 2822 O O . MET A 1 350 ? 48.456 111.046 35.737 1.00 15.15 ? 350 MET M O 1 ATOM 2823 C CB . MET A 1 350 ? 50.588 111.921 37.954 1.00 14.48 ? 350 MET M CB 1 ATOM 2824 C CG . MET A 1 350 ? 50.926 111.889 39.478 1.00 16.10 ? 350 MET M CG 1 ATOM 2825 S SD . MET A 1 350 ? 52.551 111.196 39.955 1.00 14.51 ? 350 MET M SD 1 ATOM 2826 C CE . MET A 1 350 ? 53.559 112.569 39.559 1.00 16.80 ? 350 MET M CE 1 ATOM 2827 N N . MET A 1 351 ? 50.516 110.336 35.051 1.00 10.10 ? 351 MET M N 1 ATOM 2828 C CA . MET A 1 351 ? 50.089 110.324 33.656 1.00 9.64 ? 351 MET M CA 1 ATOM 2829 C C . MET A 1 351 ? 49.125 109.237 33.303 1.00 9.88 ? 351 MET M C 1 ATOM 2830 O O . MET A 1 351 ? 48.395 109.336 32.262 1.00 10.10 ? 351 MET M O 1 ATOM 2831 C CB . MET A 1 351 ? 51.321 110.162 32.792 1.00 12.17 ? 351 MET M CB 1 ATOM 2832 C CG . MET A 1 351 ? 52.243 111.265 32.871 1.00 14.29 ? 351 MET M CG 1 ATOM 2833 S SD . MET A 1 351 ? 53.767 110.958 31.925 1.00 15.90 ? 351 MET M SD 1 ATOM 2834 C CE . MET A 1 351 ? 54.630 112.474 32.251 1.00 19.21 ? 351 MET M CE 1 ATOM 2835 N N . ASP A 1 352 ? 49.034 108.181 34.114 1.00 8.64 ? 352 ASP M N 1 ATOM 2836 C CA . ASP A 1 352 ? 48.140 107.068 33.831 1.00 9.92 ? 352 ASP M CA 1 ATOM 2837 C C . ASP A 1 352 ? 46.696 107.408 33.739 1.00 10.62 ? 352 ASP M C 1 ATOM 2838 O O . ASP A 1 352 ? 45.941 106.783 33.029 1.00 10.02 ? 352 ASP M O 1 ATOM 2839 C CB . ASP A 1 352 ? 48.328 105.956 34.827 1.00 9.56 ? 352 ASP M CB 1 ATOM 2840 C CG . ASP A 1 352 ? 49.604 105.184 34.676 1.00 12.13 ? 352 ASP M CG 1 ATOM 2841 O OD1 . ASP A 1 352 ? 50.103 104.946 33.555 1.00 11.51 ? 352 ASP M OD1 1 ATOM 2842 O OD2 . ASP A 1 352 ? 50.239 104.827 35.739 1.00 11.08 ? 352 ASP M OD2 1 ATOM 2843 N N . ALA A 1 353 ? 46.233 108.445 34.417 1.00 7.93 ? 353 ALA M N 1 ATOM 2844 C CA . ALA A 1 353 ? 44.854 108.906 34.344 1.00 8.97 ? 353 ALA M CA 1 ATOM 2845 C C . ALA A 1 353 ? 44.505 109.470 32.976 1.00 10.91 ? 353 ALA M C 1 ATOM 2846 O O . ALA A 1 353 ? 43.321 109.559 32.657 1.00 12.37 ? 353 ALA M O 1 ATOM 2847 C CB . ALA A 1 353 ? 44.617 109.986 35.433 1.00 11.94 ? 353 ALA M CB 1 ATOM 2848 N N . GLY A 1 354 ? 45.485 109.770 32.141 1.00 10.38 ? 354 GLY M N 1 ATOM 2849 C CA . GLY A 1 354 ? 45.159 110.273 30.793 1.00 11.01 ? 354 GLY M CA 1 ATOM 2850 C C . GLY A 1 354 ? 44.471 111.612 30.773 1.00 9.78 ? 354 GLY M C 1 ATOM 2851 O O . GLY A 1 354 ? 43.568 111.844 29.951 1.00 11.86 ? 354 GLY M O 1 ATOM 2852 N N . ALA A 1 355 ? 44.799 112.490 31.731 1.00 10.46 ? 355 ALA M N 1 ATOM 2853 C CA . ALA A 1 355 ? 44.087 113.736 31.893 1.00 8.79 ? 355 ALA M CA 1 ATOM 2854 C C . ALA A 1 355 ? 45.074 114.856 32.143 1.00 11.59 ? 355 ALA M C 1 ATOM 2855 O O . ALA A 1 355 ? 46.070 114.700 32.858 1.00 13.19 ? 355 ALA M O 1 ATOM 2856 C CB . ALA A 1 355 ? 43.088 113.701 33.032 1.00 11.31 ? 355 ALA M CB 1 ATOM 2857 N N . LYS A 1 356 ? 44.759 115.984 31.603 1.00 10.15 ? 356 LYS M N 1 ATOM 2858 C CA . LYS A 1 356 ? 45.442 117.262 31.849 1.00 11.55 ? 356 LYS M CA 1 ATOM 2859 C C . LYS A 1 356 ? 44.466 118.133 32.623 1.00 10.21 ? 356 LYS M C 1 ATOM 2860 O O . LYS A 1 356 ? 43.296 118.246 32.288 1.00 10.57 ? 356 LYS M O 1 ATOM 2861 C CB . LYS A 1 356 ? 45.871 117.914 30.594 1.00 10.78 ? 356 LYS M CB 1 ATOM 2862 C CG . LYS A 1 356 ? 46.281 119.415 30.765 1.00 14.39 ? 356 LYS M CG 1 ATOM 2863 C CD . LYS A 1 356 ? 46.826 120.056 29.495 1.00 20.73 ? 356 LYS M CD 1 ATOM 2864 C CE . LYS A 1 356 ? 47.437 121.469 29.812 1.00 28.14 ? 356 LYS M CE 1 ATOM 2865 N NZ . LYS A 1 356 ? 47.520 122.054 28.462 1.00 35.38 ? 356 LYS M NZ 1 ATOM 2866 N N . LEU A 1 357 ? 44.962 118.756 33.702 1.00 10.07 ? 357 LEU M N 1 ATOM 2867 C CA . LEU A 1 357 ? 44.153 119.483 34.659 1.00 8.17 ? 357 LEU M CA 1 ATOM 2868 C C . LEU A 1 357 ? 44.403 121.029 34.558 1.00 10.77 ? 357 LEU M C 1 ATOM 2869 O O . LEU A 1 357 ? 45.572 121.423 34.455 1.00 11.45 ? 357 LEU M O 1 ATOM 2870 C CB . LEU A 1 357 ? 44.450 119.013 36.100 1.00 9.61 ? 357 LEU M CB 1 ATOM 2871 C CG . LEU A 1 357 ? 44.289 117.517 36.269 1.00 11.91 ? 357 LEU M CG 1 ATOM 2872 C CD1 . LEU A 1 357 ? 44.678 117.101 37.692 1.00 14.37 ? 357 LEU M CD1 1 ATOM 2873 C CD2 . LEU A 1 357 ? 42.855 117.104 35.977 1.00 13.04 ? 357 LEU M CD2 1 ATOM 2874 N N . THR A 1 358 ? 43.357 121.798 34.535 1.00 10.26 ? 358 THR M N 1 ATOM 2875 C CA . THR A 1 358 ? 43.420 123.201 34.447 1.00 10.82 ? 358 THR M CA 1 ATOM 2876 C C . THR A 1 358 ? 42.428 123.874 35.374 1.00 10.85 ? 358 THR M C 1 ATOM 2877 O O . THR A 1 358 ? 41.540 123.218 35.921 1.00 8.84 ? 358 THR M O 1 ATOM 2878 C CB . THR A 1 358 ? 43.253 123.733 32.995 1.00 11.50 ? 358 THR M CB 1 ATOM 2879 O OG1 . THR A 1 358 ? 41.919 123.384 32.623 1.00 10.78 ? 358 THR M OG1 1 ATOM 2880 C CG2 . THR A 1 358 ? 44.312 123.141 32.050 1.00 10.53 ? 358 THR M CG2 1 ATOM 2881 N N . TYR A 1 359 ? 42.500 125.194 35.511 1.00 9.35 ? 359 TYR M N 1 ATOM 2882 C CA . TYR A 1 359 ? 41.533 125.996 36.233 1.00 8.35 ? 359 TYR M CA 1 ATOM 2883 C C . TYR A 1 359 ? 40.707 126.863 35.312 1.00 8.77 ? 359 TYR M C 1 ATOM 2884 O O . TYR A 1 359 ? 39.838 127.649 35.813 1.00 9.06 ? 359 TYR M O 1 ATOM 2885 C CB . TYR A 1 359 ? 42.214 126.871 37.350 1.00 8.62 ? 359 TYR M CB 1 ATOM 2886 C CG . TYR A 1 359 ? 42.928 125.983 38.325 1.00 9.14 ? 359 TYR M CG 1 ATOM 2887 C CD1 . TYR A 1 359 ? 42.254 125.343 39.373 1.00 11.06 ? 359 TYR M CD1 1 ATOM 2888 C CD2 . TYR A 1 359 ? 44.266 125.746 38.225 1.00 10.17 ? 359 TYR M CD2 1 ATOM 2889 C CE1 . TYR A 1 359 ? 42.855 124.513 40.212 1.00 14.45 ? 359 TYR M CE1 1 ATOM 2890 C CE2 . TYR A 1 359 ? 44.936 124.856 39.091 1.00 13.07 ? 359 TYR M CE2 1 ATOM 2891 C CZ . TYR A 1 359 ? 44.179 124.235 40.054 1.00 14.30 ? 359 TYR M CZ 1 ATOM 2892 O OH . TYR A 1 359 ? 44.806 123.377 40.887 1.00 15.50 ? 359 TYR M OH 1 ATOM 2893 N N . ILE A 1 360 ? 40.984 126.776 33.990 1.00 9.30 ? 360 ILE M N 1 ATOM 2894 C CA . ILE A 1 360 ? 40.319 127.525 32.914 1.00 8.25 ? 360 ILE M CA 1 ATOM 2895 C C . ILE A 1 360 ? 39.708 126.471 31.985 1.00 7.55 ? 360 ILE M C 1 ATOM 2896 O O . ILE A 1 360 ? 40.392 125.481 31.725 1.00 10.23 ? 360 ILE M O 1 ATOM 2897 C CB . ILE A 1 360 ? 41.254 128.505 32.156 1.00 9.51 ? 360 ILE M CB 1 ATOM 2898 C CG1 A ILE A 1 360 ? 40.519 129.174 31.055 0.60 10.12 ? 360 ILE M CG1 1 ATOM 2899 C CG1 B ILE A 1 360 ? 42.329 129.004 33.162 0.40 13.88 ? 360 ILE M CG1 1 ATOM 2900 C CG2 A ILE A 1 360 ? 42.460 127.820 31.662 0.60 11.53 ? 360 ILE M CG2 1 ATOM 2901 C CG2 B ILE A 1 360 ? 40.375 129.514 31.441 0.40 5.26 ? 360 ILE M CG2 1 ATOM 2902 C CD1 A ILE A 1 360 ? 41.293 130.303 30.444 0.60 10.41 ? 360 ILE M CD1 1 ATOM 2903 C CD1 B ILE A 1 360 ? 43.054 130.298 32.784 0.40 19.14 ? 360 ILE M CD1 1 ATOM 2904 N N . ASN A 1 361 ? 38.455 126.687 31.571 1.00 8.99 ? 361 ASN M N 1 ATOM 2905 C CA . ASN A 1 361 ? 37.832 125.781 30.638 1.00 9.68 ? 361 ASN M CA 1 ATOM 2906 C C . ASN A 1 361 ? 38.014 126.169 29.201 1.00 11.46 ? 361 ASN M C 1 ATOM 2907 O O . ASN A 1 361 ? 38.777 127.077 28.890 1.00 11.71 ? 361 ASN M O 1 ATOM 2908 C CB . ASN A 1 361 ? 36.412 125.483 31.086 1.00 9.10 ? 361 ASN M CB 1 ATOM 2909 C CG . ASN A 1 361 ? 35.394 126.460 30.655 1.00 11.53 ? 361 ASN M CG 1 ATOM 2910 O OD1 . ASN A 1 361 ? 35.755 127.498 30.089 1.00 10.51 ? 361 ASN M OD1 1 ATOM 2911 N ND2 . ASN A 1 361 ? 34.103 126.139 30.971 1.00 10.69 ? 361 ASN M ND2 1 ATOM 2912 N N . ALA A 1 362 ? 37.417 125.383 28.285 1.00 10.23 ? 362 ALA M N 1 ATOM 2913 C CA . ALA A 1 362 ? 37.787 125.561 26.894 1.00 11.25 ? 362 ALA M CA 1 ATOM 2914 C C . ALA A 1 362 ? 37.227 126.877 26.363 1.00 12.38 ? 362 ALA M C 1 ATOM 2915 O O . ALA A 1 362 ? 37.715 127.300 25.294 1.00 15.25 ? 362 ALA M O 1 ATOM 2916 C CB . ALA A 1 362 ? 37.118 124.386 26.093 1.00 11.63 ? 362 ALA M CB 1 ATOM 2917 N N . SER A 1 363 ? 36.249 127.445 26.990 1.00 10.96 ? 363 SER M N 1 ATOM 2918 C CA . SER A 1 363 ? 35.695 128.746 26.598 1.00 12.99 ? 363 SER M CA 1 ATOM 2919 C C . SER A 1 363 ? 36.359 129.935 27.283 1.00 13.47 ? 363 SER M C 1 ATOM 2920 O O . SER A 1 363 ? 35.879 131.036 27.103 1.00 14.71 ? 363 SER M O 1 ATOM 2921 C CB A SER A 1 363 ? 34.208 128.750 26.502 0.70 17.62 ? 363 SER M CB 1 ATOM 2922 C CB B SER A 1 363 ? 34.280 128.825 27.175 0.30 8.22 ? 363 SER M CB 1 ATOM 2923 O OG A SER A 1 363 ? 33.511 128.426 27.662 0.70 16.79 ? 363 SER M OG 1 ATOM 2924 O OG B SER A 1 363 ? 33.327 127.868 26.593 0.30 6.91 ? 363 SER M OG 1 ATOM 2925 N N . GLY A 1 364 ? 37.395 129.641 28.058 1.00 11.92 ? 364 GLY M N 1 ATOM 2926 C CA . GLY A 1 364 ? 38.188 130.672 28.759 1.00 13.83 ? 364 GLY M CA 1 ATOM 2927 C C . GLY A 1 364 ? 37.656 131.108 30.089 1.00 14.12 ? 364 GLY M C 1 ATOM 2928 O O . GLY A 1 364 ? 38.130 132.119 30.689 1.00 13.64 ? 364 GLY M O 1 ATOM 2929 N N . HIS A 1 365 ? 36.685 130.358 30.699 1.00 11.36 ? 365 HIS M N 1 ATOM 2930 C CA . HIS A 1 365 ? 36.162 130.653 32.001 1.00 10.93 ? 365 HIS M CA 1 ATOM 2931 C C . HIS A 1 365 ? 37.070 130.136 33.062 1.00 10.12 ? 365 HIS M C 1 ATOM 2932 O O . HIS A 1 365 ? 37.378 128.905 33.147 1.00 11.30 ? 365 HIS M O 1 ATOM 2933 C CB . HIS A 1 365 ? 34.830 129.916 32.169 1.00 10.65 ? 365 HIS M CB 1 ATOM 2934 C CG . HIS A 1 365 ? 34.156 130.113 33.441 1.00 10.92 ? 365 HIS M CG 1 ATOM 2935 N ND1 . HIS A 1 365 ? 34.014 129.155 34.440 1.00 16.71 ? 365 HIS M ND1 1 ATOM 2936 C CD2 . HIS A 1 365 ? 33.655 131.271 33.953 1.00 12.10 ? 365 HIS M CD2 1 ATOM 2937 C CE1 . HIS A 1 365 ? 33.403 129.722 35.475 1.00 9.60 ? 365 HIS M CE1 1 ATOM 2938 N NE2 . HIS A 1 365 ? 33.124 130.986 35.161 1.00 20.08 ? 365 HIS M NE2 1 ATOM 2939 N N . TYR A 1 366 ? 37.489 131.008 33.997 1.00 10.12 ? 366 TYR M N 1 ATOM 2940 C CA . TYR A 1 366 ? 38.204 130.549 35.184 1.00 10.37 ? 366 TYR M CA 1 ATOM 2941 C C . TYR A 1 366 ? 37.166 130.074 36.180 1.00 8.49 ? 366 TYR M C 1 ATOM 2942 O O . TYR A 1 366 ? 36.092 130.694 36.412 1.00 10.29 ? 366 TYR M O 1 ATOM 2943 C CB A TYR A 1 366 ? 38.891 131.776 35.847 0.70 11.27 ? 366 TYR M CB 1 ATOM 2944 C CB B TYR A 1 366 ? 39.137 131.600 35.754 0.30 8.24 ? 366 TYR M CB 1 ATOM 2945 C CG A TYR A 1 366 ? 40.151 132.268 35.179 0.70 16.25 ? 366 TYR M CG 1 ATOM 2946 C CG B TYR A 1 366 ? 40.468 131.638 35.039 0.30 6.25 ? 366 TYR M CG 1 ATOM 2947 C CD1 A TYR A 1 366 ? 40.133 132.896 33.943 0.70 21.75 ? 366 TYR M CD1 1 ATOM 2948 C CD1 B TYR A 1 366 ? 41.492 130.815 35.417 0.30 2.22 ? 366 TYR M CD1 1 ATOM 2949 C CD2 A TYR A 1 366 ? 41.358 132.020 35.734 0.70 24.57 ? 366 TYR M CD2 1 ATOM 2950 C CD2 B TYR A 1 366 ? 40.637 132.407 33.899 0.30 6.79 ? 366 TYR M CD2 1 ATOM 2951 C CE1 A TYR A 1 366 ? 41.341 133.337 33.346 0.70 22.03 ? 366 TYR M CE1 1 ATOM 2952 C CE1 B TYR A 1 366 ? 42.704 130.851 34.773 0.30 3.69 ? 366 TYR M CE1 1 ATOM 2953 C CE2 A TYR A 1 366 ? 42.547 132.470 35.125 0.70 28.53 ? 366 TYR M CE2 1 ATOM 2954 C CE2 B TYR A 1 366 ? 41.851 132.456 33.263 0.30 9.28 ? 366 TYR M CE2 1 ATOM 2955 C CZ A TYR A 1 366 ? 42.507 133.130 33.944 0.70 25.85 ? 366 TYR M CZ 1 ATOM 2956 C CZ B TYR A 1 366 ? 42.878 131.649 33.707 0.30 6.34 ? 366 TYR M CZ 1 ATOM 2957 O OH A TYR A 1 366 ? 43.725 133.489 33.349 0.70 30.59 ? 366 TYR M OH 1 ATOM 2958 O OH B TYR A 1 366 ? 44.111 131.716 33.008 0.30 10.37 ? 366 TYR M OH 1 ATOM 2959 N N . ILE A 1 367 ? 37.502 129.000 36.878 1.00 8.37 ? 367 ILE M N 1 ATOM 2960 C CA . ILE A 1 367 ? 36.522 128.290 37.699 1.00 7.07 ? 367 ILE M CA 1 ATOM 2961 C C . ILE A 1 367 ? 35.995 129.040 38.854 1.00 8.20 ? 367 ILE M C 1 ATOM 2962 O O . ILE A 1 367 ? 34.864 128.781 39.352 1.00 10.82 ? 367 ILE M O 1 ATOM 2963 C CB . ILE A 1 367 ? 37.101 126.890 38.055 1.00 8.22 ? 367 ILE M CB 1 ATOM 2964 C CG1 . ILE A 1 367 ? 35.985 125.939 38.530 1.00 10.46 ? 367 ILE M CG1 1 ATOM 2965 C CG2 . ILE A 1 367 ? 38.292 127.055 39.090 1.00 10.02 ? 367 ILE M CG2 1 ATOM 2966 C CD1 . ILE A 1 367 ? 36.493 124.489 38.704 1.00 12.48 ? 367 ILE M CD1 1 ATOM 2967 N N . GLY A 1 368 ? 36.767 129.965 39.386 1.00 8.24 ? 368 GLY M N 1 ATOM 2968 C CA . GLY A 1 368 ? 36.373 130.698 40.531 1.00 9.28 ? 368 GLY M CA 1 ATOM 2969 C C . GLY A 1 368 ? 37.425 131.759 40.912 1.00 7.96 ? 368 GLY M C 1 ATOM 2970 O O . GLY A 1 368 ? 38.345 132.010 40.104 1.00 9.12 ? 368 GLY M O 1 ATOM 2971 N N . PRO A 1 369 ? 37.342 132.284 42.123 1.00 8.15 ? 369 PRO M N 1 ATOM 2972 C CA . PRO A 1 369 ? 38.331 133.232 42.604 1.00 9.66 ? 369 PRO M CA 1 ATOM 2973 C C . PRO A 1 369 ? 39.684 132.690 42.753 1.00 10.25 ? 369 PRO M C 1 ATOM 2974 O O . PRO A 1 369 ? 39.949 131.492 42.955 1.00 8.98 ? 369 PRO M O 1 ATOM 2975 C CB . PRO A 1 369 ? 37.728 133.728 43.949 1.00 10.73 ? 369 PRO M CB 1 ATOM 2976 C CG . PRO A 1 369 ? 36.338 133.283 43.973 1.00 10.27 ? 369 PRO M CG 1 ATOM 2977 C CD . PRO A 1 369 ? 36.300 132.058 43.122 1.00 8.93 ? 369 PRO M CD 1 ATOM 2978 N N . LEU A 1 370 ? 40.676 133.595 42.757 1.00 11.19 ? 370 LEU M N 1 ATOM 2979 C CA . LEU A 1 370 ? 42.065 133.222 42.983 1.00 8.60 ? 370 LEU M CA 1 ATOM 2980 C C . LEU A 1 370 ? 42.239 132.508 44.356 1.00 10.55 ? 370 LEU M C 1 ATOM 2981 O O . LEU A 1 370 ? 41.773 132.983 45.418 1.00 10.45 ? 370 LEU M O 1 ATOM 2982 C CB . LEU A 1 370 ? 42.938 134.517 42.951 1.00 10.59 ? 370 LEU M CB 1 ATOM 2983 C CG . LEU A 1 370 ? 44.427 134.256 43.054 1.00 13.26 ? 370 LEU M CG 1 ATOM 2984 C CD1 . LEU A 1 370 ? 45.074 133.503 41.829 1.00 14.09 ? 370 LEU M CD1 1 ATOM 2985 C CD2 . LEU A 1 370 ? 45.232 135.619 43.410 1.00 18.25 ? 370 LEU M CD2 1 ATOM 2986 N N . PHE A 1 371 ? 42.988 131.431 44.279 1.00 11.14 ? 371 PHE M N 1 ATOM 2987 C CA . PHE A 1 371 ? 43.369 130.622 45.414 1.00 11.64 ? 371 PHE M CA 1 ATOM 2988 C C . PHE A 1 371 ? 44.830 130.808 45.732 1.00 14.82 ? 371 PHE M C 1 ATOM 2989 O O . PHE A 1 371 ? 45.156 130.944 46.924 1.00 17.84 ? 371 PHE M O 1 ATOM 2990 C CB . PHE A 1 371 ? 43.055 129.163 45.190 1.00 11.00 ? 371 PHE M CB 1 ATOM 2991 C CG . PHE A 1 371 ? 43.369 128.266 46.389 1.00 9.75 ? 371 PHE M CG 1 ATOM 2992 C CD1 . PHE A 1 371 ? 42.491 128.158 47.460 1.00 7.86 ? 371 PHE M CD1 1 ATOM 2993 C CD2 . PHE A 1 371 ? 44.432 127.460 46.313 1.00 16.95 ? 371 PHE M CD2 1 ATOM 2994 C CE1 . PHE A 1 371 ? 42.808 127.349 48.503 1.00 9.71 ? 371 PHE M CE1 1 ATOM 2995 C CE2 . PHE A 1 371 ? 44.782 126.635 47.387 1.00 16.19 ? 371 PHE M CE2 1 ATOM 2996 C CZ . PHE A 1 371 ? 43.931 126.629 48.492 1.00 14.43 ? 371 PHE M CZ 1 ATOM 2997 N N . GLU A 1 372 ? 45.734 130.634 44.775 1.00 15.64 ? 372 GLU M N 1 ATOM 2998 C CA . GLU A 1 372 ? 47.184 130.704 45.083 1.00 15.57 ? 372 GLU M CA 1 ATOM 2999 C C . GLU A 1 372 ? 47.820 131.222 43.852 1.00 17.99 ? 372 GLU M C 1 ATOM 3000 O O . GLU A 1 372 ? 47.786 130.586 42.770 1.00 19.12 ? 372 GLU M O 1 ATOM 3001 C CB . GLU A 1 372 ? 47.726 129.376 45.459 1.00 21.61 ? 372 GLU M CB 1 ATOM 3002 C CG . GLU A 1 372 ? 49.079 129.419 46.224 1.00 27.77 ? 372 GLU M CG 1 ATOM 3003 C CD . GLU A 1 372 ? 49.274 128.120 46.974 1.00 39.37 ? 372 GLU M CD 1 ATOM 3004 O OE1 . GLU A 1 372 ? 48.658 127.836 48.116 1.00 33.34 ? 372 GLU M OE1 1 ATOM 3005 O OE2 . GLU A 1 372 ? 49.995 127.345 46.309 1.00 44.37 ? 372 GLU M OE2 1 ATOM 3006 N N . LYS A 1 373 ? 48.450 132.359 43.957 1.00 21.47 ? 373 LYS M N 1 ATOM 3007 C CA . LYS A 1 373 ? 49.225 132.869 42.852 1.00 24.96 ? 373 LYS M CA 1 ATOM 3008 C C . LYS A 1 373 ? 50.519 132.058 42.686 1.00 26.88 ? 373 LYS M C 1 ATOM 3009 O O . LYS A 1 373 ? 51.117 131.534 43.656 1.00 27.33 ? 373 LYS M O 1 ATOM 3010 C CB . LYS A 1 373 ? 49.550 134.340 43.047 1.00 29.06 ? 373 LYS M CB 1 ATOM 3011 C CG . LYS A 1 373 ? 50.274 134.943 41.869 1.00 38.43 ? 373 LYS M CG 1 ATOM 3012 C CD . LYS A 1 373 ? 49.414 135.892 41.095 1.00 45.05 ? 373 LYS M CD 1 ATOM 3013 C CE . LYS A 1 373 ? 49.777 135.940 39.619 1.00 47.41 ? 373 LYS M CE 1 ATOM 3014 N NZ . LYS A 1 373 ? 48.701 136.682 38.917 1.00 51.79 ? 373 LYS M NZ 1 ATOM 3015 N N . ASP A 1 374 ? 50.899 131.841 41.432 1.00 26.09 ? 374 ASP M N 1 ATOM 3016 C CA . ASP A 1 374 ? 52.153 131.209 41.116 1.00 29.24 ? 374 ASP M CA 1 ATOM 3017 C C . ASP A 1 374 ? 53.005 132.332 40.527 1.00 31.21 ? 374 ASP M C 1 ATOM 3018 O O . ASP A 1 374 ? 52.782 132.744 39.374 1.00 28.58 ? 374 ASP M O 1 ATOM 3019 C CB . ASP A 1 374 ? 51.918 130.095 40.119 1.00 28.61 ? 374 ASP M CB 1 ATOM 3020 C CG . ASP A 1 374 ? 53.209 129.339 39.756 1.00 34.34 ? 374 ASP M CG 1 ATOM 3021 O OD1 . ASP A 1 374 ? 54.271 129.993 39.593 1.00 36.98 ? 374 ASP M OD1 1 ATOM 3022 O OD2 . ASP A 1 374 ? 53.099 128.107 39.628 1.00 40.61 ? 374 ASP M OD2 1 ATOM 3023 N N . LYS A 1 375 ? 53.953 132.860 41.329 1.00 34.60 ? 375 LYS M N 1 ATOM 3024 C CA . LYS A 1 375 ? 54.751 134.045 40.883 1.00 38.53 ? 375 LYS M CA 1 ATOM 3025 C C . LYS A 1 375 ? 55.621 133.746 39.662 1.00 39.34 ? 375 LYS M C 1 ATOM 3026 O O . LYS A 1 375 ? 55.719 134.557 38.717 1.00 41.97 ? 375 LYS M O 1 ATOM 3027 N N . ALA A 1 376 ? 56.182 132.541 39.649 1.00 39.34 ? 376 ALA M N 1 ATOM 3028 C CA . ALA A 1 376 ? 56.952 132.012 38.496 1.00 39.17 ? 376 ALA M CA 1 ATOM 3029 C C . ALA A 1 376 ? 56.167 131.855 37.144 1.00 38.62 ? 376 ALA M C 1 ATOM 3030 O O . ALA A 1 376 ? 56.765 132.045 36.046 1.00 37.97 ? 376 ALA M O 1 ATOM 3031 C CB . ALA A 1 376 ? 57.582 130.623 38.855 1.00 40.83 ? 376 ALA M CB 1 ATOM 3032 N N . ASP A 1 377 ? 54.880 131.452 37.188 1.00 33.78 ? 377 ASP M N 1 ATOM 3033 C CA . ASP A 1 377 ? 54.114 131.398 35.950 1.00 32.16 ? 377 ASP M CA 1 ATOM 3034 C C . ASP A 1 377 ? 52.603 131.671 36.263 1.00 29.66 ? 377 ASP M C 1 ATOM 3035 O O . ASP A 1 377 ? 51.937 130.808 36.749 1.00 28.92 ? 377 ASP M O 1 ATOM 3036 C CB . ASP A 1 377 ? 54.395 130.104 35.246 1.00 31.70 ? 377 ASP M CB 1 ATOM 3037 C CG . ASP A 1 377 ? 53.650 129.975 33.961 1.00 30.81 ? 377 ASP M CG 1 ATOM 3038 O OD1 . ASP A 1 377 ? 52.929 130.923 33.557 1.00 30.77 ? 377 ASP M OD1 1 ATOM 3039 O OD2 . ASP A 1 377 ? 53.684 128.861 33.407 1.00 31.38 ? 377 ASP M OD2 1 ATOM 3040 N N . SER A 1 378 ? 52.144 132.908 36.036 1.00 28.16 ? 378 SER M N 1 ATOM 3041 C CA . SER A 1 378 ? 50.762 133.328 36.384 1.00 28.00 ? 378 SER M CA 1 ATOM 3042 C C . SER A 1 378 ? 49.731 132.492 35.671 1.00 25.57 ? 378 SER M C 1 ATOM 3043 O O . SER A 1 378 ? 48.575 132.352 36.155 1.00 23.40 ? 378 SER M O 1 ATOM 3044 C CB . SER A 1 378 ? 50.506 134.796 36.061 1.00 29.90 ? 378 SER M CB 1 ATOM 3045 O OG . SER A 1 378 ? 51.168 135.563 37.078 1.00 41.03 ? 378 SER M OG 1 ATOM 3046 N N . THR A 1 379 ? 50.078 131.916 34.537 1.00 22.23 ? 379 THR M N 1 ATOM 3047 C CA . THR A 1 379 ? 49.120 131.074 33.818 1.00 23.45 ? 379 THR M CA 1 ATOM 3048 C C . THR A 1 379 ? 48.827 129.822 34.624 1.00 23.74 ? 379 THR M C 1 ATOM 3049 O O . THR A 1 379 ? 47.846 129.127 34.334 1.00 26.20 ? 379 THR M O 1 ATOM 3050 C CB . THR A 1 379 ? 49.609 130.662 32.439 1.00 25.05 ? 379 THR M CB 1 ATOM 3051 O OG1 . THR A 1 379 ? 50.762 129.798 32.541 1.00 25.20 ? 379 THR M OG1 1 ATOM 3052 C CG2 . THR A 1 379 ? 49.896 131.926 31.583 1.00 24.01 ? 379 THR M CG2 1 ATOM 3053 N N . ASP A 1 380 ? 49.626 129.549 35.638 1.00 23.14 ? 380 ASP M N 1 ATOM 3054 C CA . ASP A 1 380 ? 49.423 128.375 36.534 1.00 23.52 ? 380 ASP M CA 1 ATOM 3055 C C . ASP A 1 380 ? 48.924 128.704 37.963 1.00 17.63 ? 380 ASP M C 1 ATOM 3056 O O . ASP A 1 380 ? 49.036 127.853 38.890 1.00 22.31 ? 380 ASP M O 1 ATOM 3057 C CB . ASP A 1 380 ? 50.727 127.635 36.718 1.00 25.57 ? 380 ASP M CB 1 ATOM 3058 C CG . ASP A 1 380 ? 51.251 127.096 35.419 1.00 37.70 ? 380 ASP M CG 1 ATOM 3059 O OD1 . ASP A 1 380 ? 50.560 127.323 34.372 1.00 54.74 ? 380 ASP M OD1 1 ATOM 3060 O OD2 . ASP A 1 380 ? 52.311 126.406 35.463 1.00 49.77 ? 380 ASP M OD2 1 ATOM 3061 N N . ASN A 1 381 ? 48.359 129.865 38.096 1.00 17.97 ? 381 ASN M N 1 ATOM 3062 C CA . ASN A 1 381 ? 47.680 130.224 39.291 1.00 13.21 ? 381 ASN M CA 1 ATOM 3063 C C . ASN A 1 381 ? 46.589 129.151 39.598 1.00 14.63 ? 381 ASN M C 1 ATOM 3064 O O . ASN A 1 381 ? 46.017 128.524 38.679 1.00 14.33 ? 381 ASN M O 1 ATOM 3065 C CB . ASN A 1 381 ? 46.974 131.502 39.159 1.00 15.10 ? 381 ASN M CB 1 ATOM 3066 C CG . ASN A 1 381 ? 47.912 132.728 39.094 1.00 20.19 ? 381 ASN M CG 1 ATOM 3067 O OD1 . ASN A 1 381 ? 49.080 132.617 39.378 1.00 20.68 ? 381 ASN M OD1 1 ATOM 3068 N ND2 . ASN A 1 381 ? 47.320 133.873 38.863 1.00 20.58 ? 381 ASN M ND2 1 ATOM 3069 N N . ILE A 1 382 ? 46.331 128.927 40.885 1.00 12.15 ? 382 ILE M N 1 ATOM 3070 C CA . ILE A 1 382 ? 45.267 128.016 41.310 1.00 10.99 ? 382 ILE M CA 1 ATOM 3071 C C . ILE A 1 382 ? 44.096 128.934 41.631 1.00 10.84 ? 382 ILE M C 1 ATOM 3072 O O . ILE A 1 382 ? 44.238 130.013 42.206 1.00 9.98 ? 382 ILE M O 1 ATOM 3073 C CB . ILE A 1 382 ? 45.681 127.209 42.518 1.00 11.23 ? 382 ILE M CB 1 ATOM 3074 C CG1 . ILE A 1 382 ? 46.864 126.309 42.200 1.00 14.76 ? 382 ILE M CG1 1 ATOM 3075 C CG2 . ILE A 1 382 ? 44.509 126.340 43.010 1.00 12.11 ? 382 ILE M CG2 1 ATOM 3076 C CD1 . ILE A 1 382 ? 47.422 125.594 43.480 1.00 18.92 ? 382 ILE M CD1 1 ATOM 3077 N N . TYR A 1 383 ? 42.868 128.479 41.312 1.00 9.47 ? 383 TYR M N 1 ATOM 3078 C CA . TYR A 1 383 ? 41.592 129.160 41.525 1.00 8.74 ? 383 TYR M CA 1 ATOM 3079 C C . TYR A 1 383 ? 40.702 128.186 42.292 1.00 9.84 ? 383 TYR M C 1 ATOM 3080 O O . TYR A 1 383 ? 40.878 126.983 42.125 1.00 10.13 ? 383 TYR M O 1 ATOM 3081 C CB . TYR A 1 383 ? 40.922 129.608 40.200 1.00 9.54 ? 383 TYR M CB 1 ATOM 3082 C CG . TYR A 1 383 ? 41.812 130.633 39.485 1.00 10.38 ? 383 TYR M CG 1 ATOM 3083 C CD1 . TYR A 1 383 ? 42.879 130.196 38.701 1.00 10.49 ? 383 TYR M CD1 1 ATOM 3084 C CD2 . TYR A 1 383 ? 41.589 131.975 39.664 1.00 10.73 ? 383 TYR M CD2 1 ATOM 3085 C CE1 . TYR A 1 383 ? 43.699 131.107 38.071 1.00 13.71 ? 383 TYR M CE1 1 ATOM 3086 C CE2 . TYR A 1 383 ? 42.438 132.915 39.098 1.00 15.71 ? 383 TYR M CE2 1 ATOM 3087 C CZ . TYR A 1 383 ? 43.478 132.416 38.365 1.00 13.53 ? 383 TYR M CZ 1 ATOM 3088 O OH . TYR A 1 383 ? 44.290 133.420 37.693 1.00 17.21 ? 383 TYR M OH 1 ATOM 3089 N N . TYR A 1 384 ? 39.811 128.703 43.117 1.00 7.77 ? 384 TYR M N 1 ATOM 3090 C CA . TYR A 1 384 ? 38.963 127.816 43.913 1.00 7.61 ? 384 TYR M CA 1 ATOM 3091 C C . TYR A 1 384 ? 37.524 127.846 43.384 1.00 8.16 ? 384 TYR M C 1 ATOM 3092 O O . TYR A 1 384 ? 37.169 128.556 42.470 1.00 10.16 ? 384 TYR M O 1 ATOM 3093 C CB . TYR A 1 384 ? 39.065 128.165 45.371 1.00 7.75 ? 384 TYR M CB 1 ATOM 3094 C CG . TYR A 1 384 ? 38.521 129.501 45.920 1.00 6.72 ? 384 TYR M CG 1 ATOM 3095 C CD1 . TYR A 1 384 ? 37.182 129.631 46.292 1.00 9.04 ? 384 TYR M CD1 1 ATOM 3096 C CD2 . TYR A 1 384 ? 39.377 130.547 46.121 1.00 8.24 ? 384 TYR M CD2 1 ATOM 3097 C CE1 . TYR A 1 384 ? 36.693 130.778 46.892 1.00 7.98 ? 384 TYR M CE1 1 ATOM 3098 C CE2 . TYR A 1 384 ? 38.898 131.708 46.706 1.00 8.24 ? 384 TYR M CE2 1 ATOM 3099 C CZ . TYR A 1 384 ? 37.587 131.869 47.086 1.00 9.76 ? 384 TYR M CZ 1 ATOM 3100 O OH . TYR A 1 384 ? 37.072 132.984 47.731 1.00 10.64 ? 384 TYR M OH 1 ATOM 3101 N N . TYR A 1 385 ? 36.646 127.013 44.018 1.00 7.32 ? 385 TYR M N 1 ATOM 3102 C CA . TYR A 1 385 ? 35.353 126.629 43.491 1.00 7.41 ? 385 TYR M CA 1 ATOM 3103 C C . TYR A 1 385 ? 34.523 126.169 44.671 1.00 7.73 ? 385 TYR M C 1 ATOM 3104 O O . TYR A 1 385 ? 34.521 124.948 45.030 1.00 9.08 ? 385 TYR M O 1 ATOM 3105 C CB . TYR A 1 385 ? 35.501 125.541 42.452 1.00 8.82 ? 385 TYR M CB 1 ATOM 3106 C CG . TYR A 1 385 ? 34.224 125.051 41.811 1.00 9.36 ? 385 TYR M CG 1 ATOM 3107 C CD1 . TYR A 1 385 ? 33.481 125.814 40.967 1.00 10.67 ? 385 TYR M CD1 1 ATOM 3108 C CD2 . TYR A 1 385 ? 33.870 123.717 42.019 1.00 8.84 ? 385 TYR M CD2 1 ATOM 3109 C CE1 . TYR A 1 385 ? 32.370 125.293 40.356 1.00 11.71 ? 385 TYR M CE1 1 ATOM 3110 C CE2 . TYR A 1 385 ? 32.762 123.175 41.374 1.00 8.86 ? 385 TYR M CE2 1 ATOM 3111 C CZ . TYR A 1 385 ? 31.971 124.031 40.647 1.00 11.06 ? 385 TYR M CZ 1 ATOM 3112 O OH . TYR A 1 385 ? 30.807 123.553 39.992 1.00 11.36 ? 385 TYR M OH 1 ATOM 3113 N N . PRO A 1 386 ? 33.784 127.119 45.274 1.00 9.50 ? 386 PRO M N 1 ATOM 3114 C CA . PRO A 1 386 ? 33.084 126.721 46.522 1.00 9.69 ? 386 PRO M CA 1 ATOM 3115 C C . PRO A 1 386 ? 32.076 125.584 46.375 1.00 8.26 ? 386 PRO M C 1 ATOM 3116 O O . PRO A 1 386 ? 31.942 124.768 47.308 1.00 8.62 ? 386 PRO M O 1 ATOM 3117 C CB . PRO A 1 386 ? 32.435 127.994 47.002 1.00 10.92 ? 386 PRO M CB 1 ATOM 3118 C CG . PRO A 1 386 ? 33.329 129.117 46.433 1.00 12.75 ? 386 PRO M CG 1 ATOM 3119 C CD . PRO A 1 386 ? 33.808 128.583 45.069 1.00 9.31 ? 386 PRO M CD 1 ATOM 3120 N N . LYS A 1 387 ? 31.425 125.509 45.220 1.00 9.55 ? 387 LYS M N 1 ATOM 3121 C CA . LYS A 1 387 ? 30.452 124.416 44.966 1.00 9.40 ? 387 LYS M CA 1 ATOM 3122 C C . LYS A 1 387 ? 31.167 123.062 44.997 1.00 10.45 ? 387 LYS M C 1 ATOM 3123 O O . LYS A 1 387 ? 30.552 121.993 45.222 1.00 9.54 ? 387 LYS M O 1 ATOM 3124 C CB . LYS A 1 387 ? 29.724 124.659 43.668 1.00 11.05 ? 387 LYS M CB 1 ATOM 3125 C CG . LYS A 1 387 ? 28.678 123.570 43.396 1.00 12.41 ? 387 LYS M CG 1 ATOM 3126 C CD . LYS A 1 387 ? 27.783 123.930 42.265 1.00 20.36 ? 387 LYS M CD 1 ATOM 3127 C CE . LYS A 1 387 ? 26.817 122.696 41.993 1.00 27.29 ? 387 LYS M CE 1 ATOM 3128 N NZ . LYS A 1 387 ? 25.743 123.224 41.121 1.00 36.90 ? 387 LYS M NZ 1 ATOM 3129 N N . GLY A 1 388 ? 32.480 123.034 44.814 1.00 8.34 ? 388 GLY M N 1 ATOM 3130 C CA . GLY A 1 388 ? 33.196 121.760 44.823 1.00 8.94 ? 388 GLY M CA 1 ATOM 3131 C C . GLY A 1 388 ? 33.021 121.010 46.096 1.00 7.56 ? 388 GLY M C 1 ATOM 3132 O O . GLY A 1 388 ? 33.017 119.741 46.085 1.00 9.30 ? 388 GLY M O 1 ATOM 3133 N N . ILE A 1 389 ? 32.906 121.674 47.248 1.00 8.21 ? 389 ILE M N 1 ATOM 3134 C CA . ILE A 1 389 ? 32.766 120.939 48.528 1.00 8.79 ? 389 ILE M CA 1 ATOM 3135 C C . ILE A 1 389 ? 31.374 120.207 48.493 1.00 8.43 ? 389 ILE M C 1 ATOM 3136 O O . ILE A 1 389 ? 31.222 119.130 49.075 1.00 10.11 ? 389 ILE M O 1 ATOM 3137 C CB . ILE A 1 389 ? 33.052 121.803 49.773 1.00 8.39 ? 389 ILE M CB 1 ATOM 3138 C CG1 . ILE A 1 389 ? 33.306 120.861 50.951 1.00 9.74 ? 389 ILE M CG1 1 ATOM 3139 C CG2 . ILE A 1 389 ? 31.893 122.797 50.081 1.00 8.35 ? 389 ILE M CG2 1 ATOM 3140 C CD1 . ILE A 1 389 ? 33.851 121.687 52.165 1.00 12.45 ? 389 ILE M CD1 1 ATOM 3141 N N . TYR A 1 390 ? 30.345 120.865 47.976 1.00 9.84 ? 390 TYR M N 1 ATOM 3142 C CA . TYR A 1 390 ? 29.022 120.272 47.791 1.00 9.73 ? 390 TYR M CA 1 ATOM 3143 C C . TYR A 1 390 ? 29.142 119.041 46.892 1.00 9.31 ? 390 TYR M C 1 ATOM 3144 O O . TYR A 1 390 ? 28.697 117.948 47.242 1.00 9.49 ? 390 TYR M O 1 ATOM 3145 C CB . TYR A 1 390 ? 28.049 121.324 47.241 1.00 11.91 ? 390 TYR M CB 1 ATOM 3146 C CG . TYR A 1 390 ? 26.633 120.887 46.937 1.00 10.56 ? 390 TYR M CG 1 ATOM 3147 C CD1 . TYR A 1 390 ? 26.330 119.990 45.913 1.00 14.84 ? 390 TYR M CD1 1 ATOM 3148 C CD2 . TYR A 1 390 ? 25.672 121.331 47.751 1.00 11.03 ? 390 TYR M CD2 1 ATOM 3149 C CE1 . TYR A 1 390 ? 25.022 119.614 45.741 1.00 18.03 ? 390 TYR M CE1 1 ATOM 3150 C CE2 . TYR A 1 390 ? 24.270 120.955 47.524 1.00 13.93 ? 390 TYR M CE2 1 ATOM 3151 C CZ . TYR A 1 390 ? 24.033 120.163 46.576 1.00 18.21 ? 390 TYR M CZ 1 ATOM 3152 O OH . TYR A 1 390 ? 22.701 119.780 46.289 1.00 19.18 ? 390 TYR M OH 1 ATOM 3153 N N . SER A 1 391 ? 29.764 119.210 45.712 1.00 9.16 ? 391 SER M N 1 ATOM 3154 C CA . SER A 1 391 ? 29.875 118.141 44.744 1.00 7.60 ? 391 SER M CA 1 ATOM 3155 C C . SER A 1 391 ? 30.629 116.932 45.333 1.00 8.09 ? 391 SER M C 1 ATOM 3156 O O . SER A 1 391 ? 30.248 115.763 45.144 1.00 9.30 ? 391 SER M O 1 ATOM 3157 C CB . SER A 1 391 ? 30.512 118.643 43.517 1.00 10.11 ? 391 SER M CB 1 ATOM 3158 O OG . SER A 1 391 ? 29.620 119.597 42.886 1.00 11.24 ? 391 SER M OG 1 ATOM 3159 N N . VAL A 1 392 ? 31.738 117.172 46.070 1.00 8.83 ? 392 VAL M N 1 ATOM 3160 C CA . VAL A 1 392 ? 32.544 116.101 46.650 1.00 8.91 ? 392 VAL M CA 1 ATOM 3161 C C . VAL A 1 392 ? 31.700 115.317 47.684 1.00 8.29 ? 392 VAL M C 1 ATOM 3162 O O . VAL A 1 392 ? 31.689 114.090 47.711 1.00 8.64 ? 392 VAL M O 1 ATOM 3163 C CB . VAL A 1 392 ? 33.827 116.683 47.333 1.00 8.20 ? 392 VAL M CB 1 ATOM 3164 C CG1 . VAL A 1 392 ? 34.457 115.609 48.269 1.00 10.09 ? 392 VAL M CG1 1 ATOM 3165 C CG2 . VAL A 1 392 ? 34.816 117.078 46.287 1.00 9.16 ? 392 VAL M CG2 1 ATOM 3166 N N . MET A 1 393 ? 31.039 116.008 48.578 1.00 8.58 ? 393 MET M N 1 ATOM 3167 C CA . MET A 1 393 ? 30.334 115.345 49.654 1.00 9.44 ? 393 MET M CA 1 ATOM 3168 C C . MET A 1 393 ? 29.204 114.530 49.063 1.00 8.75 ? 393 MET M C 1 ATOM 3169 O O . MET A 1 393 ? 28.945 113.414 49.501 1.00 9.89 ? 393 MET M O 1 ATOM 3170 C CB . MET A 1 393 ? 29.792 116.337 50.703 1.00 9.44 ? 393 MET M CB 1 ATOM 3171 C CG . MET A 1 393 ? 30.832 117.162 51.411 1.00 11.27 ? 393 MET M CG 1 ATOM 3172 S SD . MET A 1 393 ? 32.089 116.116 52.227 1.00 14.78 ? 393 MET M SD 1 ATOM 3173 C CE . MET A 1 393 ? 33.617 117.200 51.923 1.00 16.18 ? 393 MET M CE 1 ATOM 3174 N N . ASP A 1 394 ? 28.491 115.102 48.122 1.00 8.51 ? 394 ASP M N 1 ATOM 3175 C CA . ASP A 1 394 ? 27.368 114.351 47.455 1.00 9.82 ? 394 ASP M CA 1 ATOM 3176 C C . ASP A 1 394 ? 27.913 113.124 46.794 1.00 9.77 ? 394 ASP M C 1 ATOM 3177 O O . ASP A 1 394 ? 27.335 112.053 46.854 1.00 10.99 ? 394 ASP M O 1 ATOM 3178 C CB . ASP A 1 394 ? 26.745 115.314 46.457 1.00 10.36 ? 394 ASP M CB 1 ATOM 3179 C CG . ASP A 1 394 ? 25.683 114.690 45.528 1.00 17.36 ? 394 ASP M CG 1 ATOM 3180 O OD1 . ASP A 1 394 ? 24.666 114.251 46.082 1.00 17.44 ? 394 ASP M OD1 1 ATOM 3181 O OD2 . ASP A 1 394 ? 25.949 114.562 44.298 1.00 19.45 ? 394 ASP M OD2 1 ATOM 3182 N N . TYR A 1 395 ? 29.034 113.216 46.074 1.00 9.74 ? 395 TYR M N 1 ATOM 3183 C CA . TYR A 1 395 ? 29.660 112.096 45.462 1.00 9.75 ? 395 TYR M CA 1 ATOM 3184 C C . TYR A 1 395 ? 30.031 111.059 46.474 1.00 10.17 ? 395 TYR M C 1 ATOM 3185 O O . TYR A 1 395 ? 29.836 109.846 46.216 1.00 10.37 ? 395 TYR M O 1 ATOM 3186 C CB . TYR A 1 395 ? 30.899 112.522 44.654 1.00 9.52 ? 395 TYR M CB 1 ATOM 3187 C CG . TYR A 1 395 ? 31.542 111.500 43.780 1.00 8.55 ? 395 TYR M CG 1 ATOM 3188 C CD1 . TYR A 1 395 ? 30.939 111.009 42.630 1.00 10.77 ? 395 TYR M CD1 1 ATOM 3189 C CD2 . TYR A 1 395 ? 32.735 110.921 44.111 1.00 7.81 ? 395 TYR M CD2 1 ATOM 3190 C CE1 . TYR A 1 395 ? 31.604 110.183 41.859 1.00 12.77 ? 395 TYR M CE1 1 ATOM 3191 C CE2 . TYR A 1 395 ? 33.400 110.034 43.313 1.00 10.10 ? 395 TYR M CE2 1 ATOM 3192 C CZ . TYR A 1 395 ? 32.794 109.619 42.195 1.00 12.02 ? 395 TYR M CZ 1 ATOM 3193 O OH . TYR A 1 395 ? 33.428 108.726 41.330 1.00 15.97 ? 395 TYR M OH 1 ATOM 3194 N N . PHE A 1 396 ? 30.660 111.386 47.550 1.00 7.79 ? 396 PHE M N 1 ATOM 3195 C CA . PHE A 1 396 ? 31.014 110.383 48.554 1.00 7.25 ? 396 PHE M CA 1 ATOM 3196 C C . PHE A 1 396 ? 29.778 109.662 49.103 1.00 9.28 ? 396 PHE M C 1 ATOM 3197 O O . PHE A 1 396 ? 29.835 108.435 49.261 1.00 10.56 ? 396 PHE M O 1 ATOM 3198 C CB . PHE A 1 396 ? 31.897 110.958 49.695 1.00 8.10 ? 396 PHE M CB 1 ATOM 3199 C CG . PHE A 1 396 ? 33.374 110.903 49.373 1.00 7.05 ? 396 PHE M CG 1 ATOM 3200 C CD1 . PHE A 1 396 ? 33.930 111.784 48.493 1.00 9.28 ? 396 PHE M CD1 1 ATOM 3201 C CD2 . PHE A 1 396 ? 34.165 109.947 49.968 1.00 7.51 ? 396 PHE M CD2 1 ATOM 3202 C CE1 . PHE A 1 396 ? 35.255 111.720 48.212 1.00 11.35 ? 396 PHE M CE1 1 ATOM 3203 C CE2 . PHE A 1 396 ? 35.540 109.939 49.713 1.00 9.82 ? 396 PHE M CE2 1 ATOM 3204 C CZ . PHE A 1 396 ? 36.053 110.842 48.823 1.00 10.15 ? 396 PHE M CZ 1 ATOM 3205 N N . LYS A 1 397 ? 28.707 110.436 49.361 1.00 10.21 ? 397 LYS M N 1 ATOM 3206 C CA . LYS A 1 397 ? 27.468 109.773 49.820 1.00 9.57 ? 397 LYS M CA 1 ATOM 3207 C C . LYS A 1 397 ? 26.971 108.753 48.819 1.00 9.28 ? 397 LYS M C 1 ATOM 3208 O O . LYS A 1 397 ? 26.610 107.605 49.172 1.00 12.63 ? 397 LYS M O 1 ATOM 3209 C CB . LYS A 1 397 ? 26.407 110.750 50.182 1.00 11.29 ? 397 LYS M CB 1 ATOM 3210 C CG . LYS A 1 397 ? 25.058 110.106 50.635 1.00 13.71 ? 397 LYS M CG 1 ATOM 3211 C CD . LYS A 1 397 ? 24.119 111.013 51.163 1.00 17.11 ? 397 LYS M CD 1 ATOM 3212 C CE . LYS A 1 397 ? 22.804 110.349 51.654 1.00 17.34 ? 397 LYS M CE 1 ATOM 3213 N NZ . LYS A 1 397 ? 22.056 109.870 50.475 1.00 25.13 ? 397 LYS M NZ 1 ATOM 3214 N N . ASN A 1 398 ? 26.892 109.211 47.569 1.00 10.73 ? 398 ASN M N 1 ATOM 3215 C CA . ASN A 1 398 ? 26.290 108.355 46.511 1.00 12.13 ? 398 ASN M CA 1 ATOM 3216 C C . ASN A 1 398 ? 27.131 107.228 46.051 1.00 13.03 ? 398 ASN M C 1 ATOM 3217 O O . ASN A 1 398 ? 26.605 106.108 45.743 1.00 14.77 ? 398 ASN M O 1 ATOM 3218 C CB . ASN A 1 398 ? 25.992 109.209 45.287 1.00 14.71 ? 398 ASN M CB 1 ATOM 3219 C CG . ASN A 1 398 ? 24.995 110.224 45.500 1.00 16.53 ? 398 ASN M CG 1 ATOM 3220 O OD1 . ASN A 1 398 ? 24.194 110.210 46.422 1.00 18.88 ? 398 ASN M OD1 1 ATOM 3221 N ND2 . ASN A 1 398 ? 25.067 111.275 44.632 1.00 20.41 ? 398 ASN M ND2 1 ATOM 3222 N N . LYS A 1 399 ? 28.448 107.434 45.845 1.00 11.55 ? 399 LYS M N 1 ATOM 3223 C CA . LYS A 1 399 ? 29.331 106.443 45.334 1.00 12.29 ? 399 LYS M CA 1 ATOM 3224 C C . LYS A 1 399 ? 29.924 105.535 46.388 1.00 11.22 ? 399 LYS M C 1 ATOM 3225 O O . LYS A 1 399 ? 30.280 104.380 46.135 1.00 11.60 ? 399 LYS M O 1 ATOM 3226 C CB . LYS A 1 399 ? 30.474 107.120 44.578 1.00 12.47 ? 399 LYS M CB 1 ATOM 3227 C CG . LYS A 1 399 ? 31.532 106.302 43.866 1.00 17.79 ? 399 LYS M CG 1 ATOM 3228 C CD . LYS A 1 399 ? 31.254 105.830 42.589 1.00 25.26 ? 399 LYS M CD 1 ATOM 3229 C CE . LYS A 1 399 ? 32.485 105.215 41.966 1.00 23.73 ? 399 LYS M CE 1 ATOM 3230 N NZ . LYS A 1 399 ? 31.945 104.625 40.706 1.00 34.35 ? 399 LYS M NZ 1 ATOM 3231 N N . TYR A 1 400 ? 30.134 106.055 47.607 1.00 10.08 ? 400 TYR M N 1 ATOM 3232 C CA . TYR A 1 400 ? 30.893 105.362 48.610 1.00 9.46 ? 400 TYR M CA 1 ATOM 3233 C C . TYR A 1 400 ? 30.104 105.077 49.860 1.00 10.55 ? 400 TYR M C 1 ATOM 3234 O O . TYR A 1 400 ? 30.611 105.121 51.008 1.00 12.31 ? 400 TYR M O 1 ATOM 3235 C CB . TYR A 1 400 ? 32.230 106.116 48.876 1.00 9.90 ? 400 TYR M CB 1 ATOM 3236 C CG . TYR A 1 400 ? 33.140 106.107 47.675 1.00 9.86 ? 400 TYR M CG 1 ATOM 3237 C CD1 . TYR A 1 400 ? 33.492 104.901 46.981 1.00 9.87 ? 400 TYR M CD1 1 ATOM 3238 C CD2 . TYR A 1 400 ? 33.662 107.301 47.174 1.00 11.68 ? 400 TYR M CD2 1 ATOM 3239 C CE1 . TYR A 1 400 ? 34.280 104.903 45.901 1.00 11.36 ? 400 TYR M CE1 1 ATOM 3240 C CE2 . TYR A 1 400 ? 34.481 107.286 46.087 1.00 10.55 ? 400 TYR M CE2 1 ATOM 3241 C CZ . TYR A 1 400 ? 34.780 106.116 45.444 1.00 11.53 ? 400 TYR M CZ 1 ATOM 3242 O OH . TYR A 1 400 ? 35.672 106.196 44.355 1.00 14.51 ? 400 TYR M OH 1 ATOM 3243 N N . TYR A 1 401 ? 28.831 104.724 49.681 1.00 12.22 ? 401 TYR M N 1 ATOM 3244 C CA . TYR A 1 401 ? 28.074 104.075 50.720 1.00 12.33 ? 401 TYR M CA 1 ATOM 3245 C C . TYR A 1 401 ? 27.770 104.935 51.940 1.00 11.76 ? 401 TYR M C 1 ATOM 3246 O O . TYR A 1 401 ? 27.798 104.435 53.073 1.00 11.86 ? 401 TYR M O 1 ATOM 3247 C CB . TYR A 1 401 ? 28.705 102.744 51.103 1.00 12.75 ? 401 TYR M CB 1 ATOM 3248 C CG . TYR A 1 401 ? 28.885 101.832 49.919 1.00 13.87 ? 401 TYR M CG 1 ATOM 3249 C CD1 . TYR A 1 401 ? 27.807 101.165 49.413 1.00 19.22 ? 401 TYR M CD1 1 ATOM 3250 C CD2 . TYR A 1 401 ? 30.096 101.656 49.270 1.00 14.82 ? 401 TYR M CD2 1 ATOM 3251 C CE1 . TYR A 1 401 ? 27.969 100.298 48.304 1.00 25.23 ? 401 TYR M CE1 1 ATOM 3252 C CE2 . TYR A 1 401 ? 30.236 100.917 48.187 1.00 18.89 ? 401 TYR M CE2 1 ATOM 3253 C CZ . TYR A 1 401 ? 29.165 100.169 47.717 1.00 26.48 ? 401 TYR M CZ 1 ATOM 3254 O OH . TYR A 1 401 ? 29.344 99.364 46.579 1.00 25.27 ? 401 TYR M OH 1 ATOM 3255 N N . ASN A 1 402 ? 27.439 106.215 51.715 1.00 10.17 ? 402 ASN M N 1 ATOM 3256 C CA . ASN A 1 402 ? 26.930 107.101 52.733 1.00 10.02 ? 402 ASN M CA 1 ATOM 3257 C C . ASN A 1 402 ? 27.774 107.088 54.018 1.00 10.07 ? 402 ASN M C 1 ATOM 3258 O O . ASN A 1 402 ? 27.350 106.718 55.124 1.00 10.94 ? 402 ASN M O 1 ATOM 3259 C CB . ASN A 1 402 ? 25.520 106.673 53.087 1.00 10.80 ? 402 ASN M CB 1 ATOM 3260 C CG . ASN A 1 402 ? 24.844 107.575 54.063 1.00 13.86 ? 402 ASN M CG 1 ATOM 3261 O OD1 . ASN A 1 402 ? 25.053 108.788 54.131 1.00 13.77 ? 402 ASN M OD1 1 ATOM 3262 N ND2 . ASN A 1 402 ? 23.979 106.907 54.971 1.00 17.51 ? 402 ASN M ND2 1 ATOM 3263 N N . PRO A 1 403 ? 29.086 107.463 53.918 1.00 9.45 ? 403 PRO M N 1 ATOM 3264 C CA . PRO A 1 403 ? 29.992 107.431 55.047 1.00 9.34 ? 403 PRO M CA 1 ATOM 3265 C C . PRO A 1 403 ? 29.730 108.565 56.012 1.00 8.35 ? 403 PRO M C 1 ATOM 3266 O O . PRO A 1 403 ? 29.179 109.640 55.628 1.00 10.28 ? 403 PRO M O 1 ATOM 3267 C CB . PRO A 1 403 ? 31.341 107.628 54.397 1.00 10.45 ? 403 PRO M CB 1 ATOM 3268 C CG . PRO A 1 403 ? 31.048 108.427 53.202 1.00 9.35 ? 403 PRO M CG 1 ATOM 3269 C CD . PRO A 1 403 ? 29.681 108.029 52.700 1.00 9.94 ? 403 PRO M CD 1 ATOM 3270 N N . LEU A 1 404 ? 30.159 108.365 57.245 1.00 8.85 ? 404 LEU M N 1 ATOM 3271 C CA . LEU A 1 404 ? 30.339 109.453 58.210 1.00 9.15 ? 404 LEU M CA 1 ATOM 3272 C C . LEU A 1 404 ? 31.621 110.222 57.808 1.00 9.67 ? 404 LEU M C 1 ATOM 3273 O O . LEU A 1 404 ? 32.620 109.575 57.611 1.00 9.37 ? 404 LEU M O 1 ATOM 3274 C CB . LEU A 1 404 ? 30.449 108.932 59.633 1.00 8.99 ? 404 LEU M CB 1 ATOM 3275 C CG . LEU A 1 404 ? 30.819 109.834 60.777 1.00 9.14 ? 404 LEU M CG 1 ATOM 3276 C CD1 . LEU A 1 404 ? 29.847 110.927 60.900 1.00 9.82 ? 404 LEU M CD1 1 ATOM 3277 C CD2 . LEU A 1 404 ? 30.966 109.048 62.074 1.00 12.33 ? 404 LEU M CD2 1 ATOM 3278 N N . ILE A 1 405 ? 31.489 111.542 57.708 1.00 9.15 ? 405 ILE M N 1 ATOM 3279 C CA . ILE A 1 405 ? 32.543 112.434 57.238 1.00 8.16 ? 405 ILE M CA 1 ATOM 3280 C C . ILE A 1 405 ? 32.778 113.522 58.225 1.00 8.32 ? 405 ILE M C 1 ATOM 3281 O O . ILE A 1 405 ? 31.900 114.096 58.793 1.00 8.36 ? 405 ILE M O 1 ATOM 3282 C CB . ILE A 1 405 ? 32.066 113.038 55.927 1.00 7.93 ? 405 ILE M CB 1 ATOM 3283 C CG1 . ILE A 1 405 ? 32.064 112.015 54.877 1.00 8.50 ? 405 ILE M CG1 1 ATOM 3284 C CG2 . ILE A 1 405 ? 33.020 114.180 55.468 1.00 8.51 ? 405 ILE M CG2 1 ATOM 3285 C CD1 . ILE A 1 405 ? 31.231 112.370 53.622 1.00 10.28 ? 405 ILE M CD1 1 ATOM 3286 N N . TYR A 1 406 ? 34.057 113.802 58.422 1.00 8.07 ? 406 TYR M N 1 ATOM 3287 C CA . TYR A 1 406 ? 34.501 115.069 59.052 1.00 7.89 ? 406 TYR M CA 1 ATOM 3288 C C . TYR A 1 406 ? 35.417 115.758 58.042 1.00 9.56 ? 406 TYR M C 1 ATOM 3289 O O . TYR A 1 406 ? 36.262 115.124 57.412 1.00 9.83 ? 406 TYR M O 1 ATOM 3290 C CB . TYR A 1 406 ? 35.316 114.810 60.368 1.00 8.72 ? 406 TYR M CB 1 ATOM 3291 C CG . TYR A 1 406 ? 34.406 114.217 61.486 1.00 8.37 ? 406 TYR M CG 1 ATOM 3292 C CD1 . TYR A 1 406 ? 34.218 112.858 61.542 1.00 11.91 ? 406 TYR M CD1 1 ATOM 3293 C CD2 . TYR A 1 406 ? 33.792 115.090 62.381 1.00 12.25 ? 406 TYR M CD2 1 ATOM 3294 C CE1 . TYR A 1 406 ? 33.371 112.349 62.512 1.00 12.67 ? 406 TYR M CE1 1 ATOM 3295 C CE2 . TYR A 1 406 ? 32.967 114.568 63.360 1.00 11.46 ? 406 TYR M CE2 1 ATOM 3296 C CZ . TYR A 1 406 ? 32.799 113.183 63.354 1.00 14.28 ? 406 TYR M CZ 1 ATOM 3297 O OH . TYR A 1 406 ? 31.889 112.706 64.319 1.00 19.44 ? 406 TYR M OH 1 ATOM 3298 N N . VAL A 1 407 ? 35.147 117.049 57.815 1.00 8.02 ? 407 VAL M N 1 ATOM 3299 C CA . VAL A 1 407 ? 36.005 117.860 56.957 1.00 7.18 ? 407 VAL M CA 1 ATOM 3300 C C . VAL A 1 407 ? 37.219 118.190 57.771 1.00 7.90 ? 407 VAL M C 1 ATOM 3301 O O . VAL A 1 407 ? 37.113 118.969 58.752 1.00 9.31 ? 407 VAL M O 1 ATOM 3302 C CB . VAL A 1 407 ? 35.308 119.048 56.391 1.00 9.20 ? 407 VAL M CB 1 ATOM 3303 C CG1 . VAL A 1 407 ? 36.323 119.937 55.609 1.00 10.14 ? 407 VAL M CG1 1 ATOM 3304 C CG2 . VAL A 1 407 ? 34.108 118.693 55.548 1.00 9.41 ? 407 VAL M CG2 1 ATOM 3305 N N . THR A 1 408 ? 38.371 117.570 57.466 1.00 7.15 ? 408 THR M N 1 ATOM 3306 C CA . THR A 1 408 ? 39.552 117.621 58.301 1.00 8.26 ? 408 THR M CA 1 ATOM 3307 C C . THR A 1 408 ? 40.567 118.691 57.868 1.00 8.49 ? 408 THR M C 1 ATOM 3308 O O . THR A 1 408 ? 41.488 118.927 58.685 1.00 9.96 ? 408 THR M O 1 ATOM 3309 C CB . THR A 1 408 ? 40.208 116.236 58.427 1.00 8.12 ? 408 THR M CB 1 ATOM 3310 O OG1 . THR A 1 408 ? 40.109 115.535 57.181 1.00 9.36 ? 408 THR M OG1 1 ATOM 3311 C CG2 . THR A 1 408 ? 39.410 115.397 59.500 1.00 8.93 ? 408 THR M CG2 1 ATOM 3312 N N . GLU A 1 409 ? 40.385 119.332 56.718 1.00 7.80 ? 409 GLU M N 1 ATOM 3313 C CA . GLU A 1 409 ? 41.131 120.484 56.327 1.00 7.87 ? 409 GLU M CA 1 ATOM 3314 C C . GLU A 1 409 ? 40.306 121.203 55.268 1.00 7.43 ? 409 GLU M C 1 ATOM 3315 O O . GLU A 1 409 ? 39.767 120.560 54.354 1.00 7.58 ? 409 GLU M O 1 ATOM 3316 C CB . GLU A 1 409 ? 42.511 120.218 55.659 1.00 8.49 ? 409 GLU M CB 1 ATOM 3317 C CG . GLU A 1 409 ? 43.509 119.578 56.517 1.00 9.59 ? 409 GLU M CG 1 ATOM 3318 C CD . GLU A 1 409 ? 44.886 119.286 55.919 1.00 15.90 ? 409 GLU M CD 1 ATOM 3319 O OE1 . GLU A 1 409 ? 45.240 119.921 54.907 1.00 13.29 ? 409 GLU M OE1 1 ATOM 3320 O OE2 . GLU A 1 409 ? 45.581 118.368 56.510 1.00 14.59 ? 409 GLU M OE2 1 ATOM 3321 N N . ASN A 1 410 ? 40.352 122.529 55.303 1.00 6.48 ? 410 ASN M N 1 ATOM 3322 C CA . ASN A 1 410 ? 39.834 123.421 54.295 1.00 6.71 ? 410 ASN M CA 1 ATOM 3323 C C . ASN A 1 410 ? 40.422 124.784 54.612 1.00 6.92 ? 410 ASN M C 1 ATOM 3324 O O . ASN A 1 410 ? 40.261 125.246 55.731 1.00 8.94 ? 410 ASN M O 1 ATOM 3325 C CB . ASN A 1 410 ? 38.286 123.416 54.344 1.00 8.28 ? 410 ASN M CB 1 ATOM 3326 C CG . ASN A 1 410 ? 37.615 124.380 53.341 1.00 10.37 ? 410 ASN M CG 1 ATOM 3327 O OD1 . ASN A 1 410 ? 36.916 125.313 53.743 1.00 10.46 ? 410 ASN M OD1 1 ATOM 3328 N ND2 . ASN A 1 410 ? 37.818 124.140 52.043 1.00 8.42 ? 410 ASN M ND2 1 ATOM 3329 N N . GLY A 1 411 ? 41.057 125.445 53.656 1.00 7.56 ? 411 GLY M N 1 ATOM 3330 C CA . GLY A 1 411 ? 41.622 126.780 53.947 1.00 8.42 ? 411 GLY M CA 1 ATOM 3331 C C . GLY A 1 411 ? 42.294 127.338 52.722 1.00 8.85 ? 411 GLY M C 1 ATOM 3332 O O . GLY A 1 411 ? 42.359 126.720 51.676 1.00 8.28 ? 411 GLY M O 1 ATOM 3333 N N . ILE A 1 412 ? 42.952 128.505 52.907 1.00 7.30 ? 412 ILE M N 1 ATOM 3334 C CA . ILE A 1 412 ? 43.533 129.280 51.793 1.00 6.67 ? 412 ILE M CA 1 ATOM 3335 C C . ILE A 1 412 ? 44.743 130.047 52.339 1.00 7.50 ? 412 ILE M C 1 ATOM 3336 O O . ILE A 1 412 ? 44.780 130.425 53.494 1.00 10.93 ? 412 ILE M O 1 ATOM 3337 C CB . ILE A 1 412 ? 42.471 130.245 51.140 1.00 7.97 ? 412 ILE M CB 1 ATOM 3338 C CG1 . ILE A 1 412 ? 42.981 130.934 49.909 1.00 7.12 ? 412 ILE M CG1 1 ATOM 3339 C CG2 . ILE A 1 412 ? 41.911 131.219 52.191 1.00 8.81 ? 412 ILE M CG2 1 ATOM 3340 C CD1 . ILE A 1 412 ? 41.948 131.627 49.046 1.00 8.63 ? 412 ILE M CD1 1 ATOM 3341 N N . SER A 1 413 ? 45.702 130.233 51.433 1.00 10.19 ? 413 SER M N 1 ATOM 3342 C CA . SER A 1 413 ? 46.899 130.982 51.856 1.00 11.20 ? 413 SER M CA 1 ATOM 3343 C C . SER A 1 413 ? 46.801 132.421 51.398 1.00 11.04 ? 413 SER M C 1 ATOM 3344 O O . SER A 1 413 ? 45.968 132.844 50.548 1.00 12.43 ? 413 SER M O 1 ATOM 3345 C CB . SER A 1 413 ? 48.116 130.437 51.234 1.00 12.44 ? 413 SER M CB 1 ATOM 3346 O OG . SER A 1 413 ? 48.203 130.555 49.831 1.00 19.68 ? 413 SER M OG 1 ATOM 3347 N N . THR A 1 414 ? 47.638 133.210 52.082 1.00 12.17 ? 414 THR M N 1 ATOM 3348 C CA . THR A 1 414 ? 47.925 134.635 51.676 1.00 12.34 ? 414 THR M CA 1 ATOM 3349 C C . THR A 1 414 ? 49.470 134.659 51.548 1.00 13.88 ? 414 THR M C 1 ATOM 3350 O O . THR A 1 414 ? 50.242 133.877 52.149 1.00 13.48 ? 414 THR M O 1 ATOM 3351 C CB . THR A 1 414 ? 47.410 135.672 52.626 1.00 16.76 ? 414 THR M CB 1 ATOM 3352 O OG1 . THR A 1 414 ? 47.935 135.412 53.926 1.00 17.17 ? 414 THR M OG1 1 ATOM 3353 C CG2 . THR A 1 414 ? 45.827 135.640 52.747 1.00 17.78 ? 414 THR M CG2 1 ATOM 3354 N N . PRO A 1 415 ? 49.983 135.544 50.707 1.00 14.80 ? 415 PRO M N 1 ATOM 3355 C CA . PRO A 1 415 ? 51.432 135.545 50.489 1.00 15.52 ? 415 PRO M CA 1 ATOM 3356 C C . PRO A 1 415 ? 52.272 135.963 51.676 1.00 17.06 ? 415 PRO M C 1 ATOM 3357 O O . PRO A 1 415 ? 51.936 136.827 52.411 1.00 19.54 ? 415 PRO M O 1 ATOM 3358 C CB . PRO A 1 415 ? 51.644 136.563 49.297 1.00 19.80 ? 415 PRO M CB 1 ATOM 3359 C CG . PRO A 1 415 ? 50.279 136.622 48.648 1.00 19.07 ? 415 PRO M CG 1 ATOM 3360 C CD . PRO A 1 415 ? 49.247 136.397 49.755 1.00 18.09 ? 415 PRO M CD 1 ATOM 3361 N N . GLY A 1 416 ? 53.397 135.275 51.838 1.00 17.42 ? 416 GLY M N 1 ATOM 3362 C CA . GLY A 1 416 ? 54.324 135.647 52.879 1.00 18.98 ? 416 GLY M CA 1 ATOM 3363 C C . GLY A 1 416 ? 54.996 137.040 52.609 1.00 21.46 ? 416 GLY M C 1 ATOM 3364 O O . GLY A 1 416 ? 55.441 137.657 53.541 1.00 24.13 ? 416 GLY M O 1 ATOM 3365 N N . ASP A 1 417 ? 54.983 137.555 51.346 1.00 25.54 ? 417 ASP M N 1 ATOM 3366 C CA . ASP A 1 417 ? 55.536 138.920 50.994 1.00 26.08 ? 417 ASP M CA 1 ATOM 3367 C C . ASP A 1 417 ? 54.704 140.010 51.640 1.00 26.20 ? 417 ASP M C 1 ATOM 3368 O O . ASP A 1 417 ? 55.151 141.174 51.769 1.00 26.39 ? 417 ASP M O 1 ATOM 3369 C CB . ASP A 1 417 ? 55.547 139.194 49.462 1.00 26.69 ? 417 ASP M CB 1 ATOM 3370 N N . GLU A 1 418 ? 53.448 139.705 52.032 1.00 23.89 ? 418 GLU M N 1 ATOM 3371 C CA . GLU A 1 418 ? 52.638 140.716 52.679 1.00 21.37 ? 418 GLU M CA 1 ATOM 3372 C C . GLU A 1 418 ? 53.286 141.101 54.030 1.00 20.71 ? 418 GLU M C 1 ATOM 3373 O O . GLU A 1 418 ? 53.941 140.289 54.675 1.00 22.14 ? 418 GLU M O 1 ATOM 3374 C CB . GLU A 1 418 ? 51.167 140.251 52.868 1.00 22.98 ? 418 GLU M CB 1 ATOM 3375 C CG . GLU A 1 418 ? 50.352 140.171 51.587 1.00 22.22 ? 418 GLU M CG 1 ATOM 3376 C CD . GLU A 1 418 ? 48.955 139.644 51.804 1.00 27.12 ? 418 GLU M CD 1 ATOM 3377 O OE1 . GLU A 1 418 ? 48.537 139.233 52.962 1.00 22.91 ? 418 GLU M OE1 1 ATOM 3378 O OE2 . GLU A 1 418 ? 48.266 139.688 50.710 1.00 32.76 ? 418 GLU M OE2 1 ATOM 3379 N N . ASN A 1 419 ? 53.121 142.323 54.472 1.00 20.87 ? 419 ASN M N 1 ATOM 3380 C CA . ASN A 1 419 ? 53.486 142.776 55.832 1.00 20.21 ? 419 ASN M CA 1 ATOM 3381 C C . ASN A 1 419 ? 52.433 142.414 56.847 1.00 21.36 ? 419 ASN M C 1 ATOM 3382 O O . ASN A 1 419 ? 51.404 141.817 56.465 1.00 19.68 ? 419 ASN M O 1 ATOM 3383 C CB . ASN A 1 419 ? 53.756 144.328 55.863 1.00 24.56 ? 419 ASN M CB 1 ATOM 3384 C CG . ASN A 1 419 ? 52.515 145.164 55.597 1.00 25.81 ? 419 ASN M CG 1 ATOM 3385 O OD1 . ASN A 1 419 ? 51.377 144.869 56.042 1.00 23.35 ? 419 ASN M OD1 1 ATOM 3386 N ND2 . ASN A 1 419 ? 52.747 146.322 54.946 1.00 30.67 ? 419 ASN M ND2 1 ATOM 3387 N N . ARG A 1 420 ? 52.701 142.664 58.122 1.00 19.64 ? 420 ARG M N 1 ATOM 3388 C CA . ARG A 1 420 ? 51.814 142.211 59.143 1.00 19.58 ? 420 ARG M CA 1 ATOM 3389 C C . ARG A 1 420 ? 50.367 142.743 59.022 1.00 22.31 ? 420 ARG M C 1 ATOM 3390 O O . ARG A 1 420 ? 49.359 142.038 59.280 1.00 20.36 ? 420 ARG M O 1 ATOM 3391 C CB . ARG A 1 420 ? 52.311 142.630 60.493 1.00 21.35 ? 420 ARG M CB 1 ATOM 3392 C CG . ARG A 1 420 ? 51.480 142.170 61.613 1.00 21.26 ? 420 ARG M CG 1 ATOM 3393 C CD . ARG A 1 420 ? 51.995 142.542 62.969 1.00 27.84 ? 420 ARG M CD 1 ATOM 3394 N NE . ARG A 1 420 ? 51.263 141.864 64.023 1.00 34.65 ? 420 ARG M NE 1 ATOM 3395 C CZ . ARG A 1 420 ? 50.088 142.200 64.553 1.00 45.47 ? 420 ARG M CZ 1 ATOM 3396 N NH1 . ARG A 1 420 ? 49.419 143.329 64.189 1.00 45.80 ? 420 ARG M NH1 1 ATOM 3397 N NH2 . ARG A 1 420 ? 49.586 141.382 65.486 1.00 47.03 ? 420 ARG M NH2 1 ATOM 3398 N N . ASN A 1 421 ? 50.225 144.040 58.722 1.00 23.01 ? 421 ASN M N 1 ATOM 3399 C CA . ASN A 1 421 ? 48.927 144.610 58.606 1.00 22.24 ? 421 ASN M CA 1 ATOM 3400 C C . ASN A 1 421 ? 48.156 143.962 57.501 1.00 17.79 ? 421 ASN M C 1 ATOM 3401 O O . ASN A 1 421 ? 46.994 143.615 57.710 1.00 20.88 ? 421 ASN M O 1 ATOM 3402 C CB . ASN A 1 421 ? 49.073 146.122 58.310 1.00 25.12 ? 421 ASN M CB 1 ATOM 3403 C CG . ASN A 1 421 ? 49.284 146.955 59.560 1.00 34.48 ? 421 ASN M CG 1 ATOM 3404 O OD1 . ASN A 1 421 ? 49.339 146.440 60.679 1.00 43.62 ? 421 ASN M OD1 1 ATOM 3405 N ND2 . ASN A 1 421 ? 49.424 148.305 59.352 1.00 45.64 ? 421 ASN M ND2 1 ATOM 3406 N N . GLN A 1 422 ? 48.785 143.769 56.371 1.00 17.27 ? 422 GLN M N 1 ATOM 3407 C CA . GLN A 1 422 ? 48.154 143.207 55.191 1.00 17.85 ? 422 GLN M CA 1 ATOM 3408 C C . GLN A 1 422 ? 47.744 141.786 55.601 1.00 17.85 ? 422 GLN M C 1 ATOM 3409 O O . GLN A 1 422 ? 46.630 141.355 55.237 1.00 17.15 ? 422 GLN M O 1 ATOM 3410 C CB . GLN A 1 422 ? 49.118 143.195 54.041 1.00 19.32 ? 422 GLN M CB 1 ATOM 3411 C CG . GLN A 1 422 ? 49.399 144.612 53.509 1.00 21.99 ? 422 GLN M CG 1 ATOM 3412 C CD . GLN A 1 422 ? 50.569 144.661 52.502 1.00 23.63 ? 422 GLN M CD 1 ATOM 3413 O OE1 . GLN A 1 422 ? 51.489 143.844 52.447 1.00 21.93 ? 422 GLN M OE1 1 ATOM 3414 N NE2 . GLN A 1 422 ? 50.551 145.740 51.704 1.00 29.36 ? 422 GLN M NE2 1 ATOM 3415 N N . SER A 1 423 ? 48.665 141.066 56.206 1.00 16.75 ? 423 SER M N 1 ATOM 3416 C CA . SER A 1 423 ? 48.397 139.641 56.580 1.00 15.80 ? 423 SER M CA 1 ATOM 3417 C C . SER A 1 423 ? 47.263 139.535 57.543 1.00 14.81 ? 423 SER M C 1 ATOM 3418 O O . SER A 1 423 ? 46.474 138.526 57.479 1.00 16.29 ? 423 SER M O 1 ATOM 3419 C CB . SER A 1 423 ? 49.649 138.980 57.210 1.00 17.99 ? 423 SER M CB 1 ATOM 3420 O OG . SER A 1 423 ? 50.695 139.020 56.266 1.00 20.28 ? 423 SER M OG 1 ATOM 3421 N N . MET A 1 424 ? 47.097 140.447 58.487 1.00 14.87 ? 424 MET M N 1 ATOM 3422 C CA . MET A 1 424 ? 45.992 140.410 59.454 1.00 15.69 ? 424 MET M CA 1 ATOM 3423 C C . MET A 1 424 ? 44.618 140.743 58.815 1.00 14.16 ? 424 MET M C 1 ATOM 3424 O O . MET A 1 424 ? 43.572 140.281 59.327 1.00 13.87 ? 424 MET M O 1 ATOM 3425 C CB . MET A 1 424 ? 46.206 141.389 60.630 1.00 19.44 ? 424 MET M CB 1 ATOM 3426 C CG . MET A 1 424 ? 47.423 141.113 61.381 1.00 26.05 ? 424 MET M CG 1 ATOM 3427 S SD . MET A 1 424 ? 47.166 139.865 62.572 1.00 30.99 ? 424 MET M SD 1 ATOM 3428 C CE . MET A 1 424 ? 46.035 140.468 63.826 1.00 28.50 ? 424 MET M CE 1 ATOM 3429 N N . LEU A 1 425 ? 44.642 141.591 57.784 1.00 13.70 ? 425 LEU M N 1 ATOM 3430 C CA . LEU A 1 425 ? 43.451 141.952 57.017 1.00 13.28 ? 425 LEU M CA 1 ATOM 3431 C C . LEU A 1 425 ? 43.097 140.964 55.918 1.00 13.58 ? 425 LEU M C 1 ATOM 3432 O O . LEU A 1 425 ? 43.101 141.230 54.718 1.00 14.91 ? 425 LEU M O 1 ATOM 3433 C CB . LEU A 1 425 ? 43.596 143.383 56.418 1.00 13.69 ? 425 LEU M CB 1 ATOM 3434 C CG . LEU A 1 425 ? 43.684 144.361 57.574 1.00 16.75 ? 425 LEU M CG 1 ATOM 3435 C CD1 . LEU A 1 425 ? 43.972 145.686 56.741 1.00 18.39 ? 425 LEU M CD1 1 ATOM 3436 C CD2 . LEU A 1 425 ? 42.467 144.496 58.414 1.00 19.08 ? 425 LEU M CD2 1 ATOM 3437 N N . ASP A 1 426 ? 42.901 139.737 56.409 1.00 14.03 ? 426 ASP M N 1 ATOM 3438 C CA . ASP A 1 426 ? 42.795 138.547 55.472 1.00 11.74 ? 426 ASP M CA 1 ATOM 3439 C C . ASP A 1 426 ? 41.378 138.311 55.041 1.00 13.13 ? 426 ASP M C 1 ATOM 3440 O O . ASP A 1 426 ? 40.764 137.247 55.179 1.00 10.19 ? 426 ASP M O 1 ATOM 3441 C CB . ASP A 1 426 ? 43.437 137.351 56.105 1.00 12.44 ? 426 ASP M CB 1 ATOM 3442 C CG . ASP A 1 426 ? 42.799 136.933 57.340 1.00 12.00 ? 426 ASP M CG 1 ATOM 3443 O OD1 . ASP A 1 426 ? 42.071 137.646 58.065 1.00 13.17 ? 426 ASP M OD1 1 ATOM 3444 O OD2 . ASP A 1 426 ? 42.943 135.702 57.646 1.00 13.12 ? 426 ASP M OD2 1 ATOM 3445 N N . TYR A 1 427 ? 40.743 139.338 54.422 1.00 11.19 ? 427 TYR M N 1 ATOM 3446 C CA . TYR A 1 427 ? 39.377 139.172 54.012 1.00 12.61 ? 427 TYR M CA 1 ATOM 3447 C C . TYR A 1 427 ? 39.173 138.099 52.951 1.00 10.01 ? 427 TYR M C 1 ATOM 3448 O O . TYR A 1 427 ? 38.116 137.503 52.830 1.00 10.99 ? 427 TYR M O 1 ATOM 3449 C CB . TYR A 1 427 ? 38.813 140.506 53.432 1.00 13.90 ? 427 TYR M CB 1 ATOM 3450 C CG . TYR A 1 427 ? 38.850 141.654 54.432 1.00 13.55 ? 427 TYR M CG 1 ATOM 3451 C CD1 . TYR A 1 427 ? 37.928 141.746 55.386 1.00 18.51 ? 427 TYR M CD1 1 ATOM 3452 C CD2 . TYR A 1 427 ? 39.859 142.626 54.308 1.00 15.15 ? 427 TYR M CD2 1 ATOM 3453 C CE1 . TYR A 1 427 ? 37.923 142.815 56.298 1.00 20.92 ? 427 TYR M CE1 1 ATOM 3454 C CE2 . TYR A 1 427 ? 39.881 143.692 55.206 1.00 18.24 ? 427 TYR M CE2 1 ATOM 3455 C CZ . TYR A 1 427 ? 38.904 143.728 56.161 1.00 14.39 ? 427 TYR M CZ 1 ATOM 3456 O OH . TYR A 1 427 ? 38.995 144.892 57.038 1.00 20.37 ? 427 TYR M OH 1 ATOM 3457 N N . THR A 1 428 ? 40.205 137.865 52.145 1.00 10.49 ? 428 THR M N 1 ATOM 3458 C CA . THR A 1 428 ? 40.187 136.746 51.166 1.00 10.84 ? 428 THR M CA 1 ATOM 3459 C C . THR A 1 428 ? 39.959 135.378 51.875 1.00 9.76 ? 428 THR M C 1 ATOM 3460 O O . THR A 1 428 ? 39.364 134.490 51.242 1.00 9.63 ? 428 THR M O 1 ATOM 3461 C CB . THR A 1 428 ? 41.431 136.666 50.296 1.00 12.04 ? 428 THR M CB 1 ATOM 3462 O OG1 . THR A 1 428 ? 42.612 136.558 51.111 1.00 13.57 ? 428 THR M OG1 1 ATOM 3463 C CG2 . THR A 1 428 ? 41.583 137.871 49.356 1.00 13.82 ? 428 THR M CG2 1 ATOM 3464 N N . ARG A 1 429 ? 40.427 135.215 53.092 1.00 10.77 ? 429 ARG M N 1 ATOM 3465 C CA . ARG A 1 429 ? 40.297 134.009 53.860 1.00 10.29 ? 429 ARG M CA 1 ATOM 3466 C C . ARG A 1 429 ? 38.926 133.872 54.423 1.00 10.42 ? 429 ARG M C 1 ATOM 3467 O O . ARG A 1 429 ? 38.285 132.802 54.369 1.00 10.19 ? 429 ARG M O 1 ATOM 3468 C CB . ARG A 1 429 ? 41.359 133.916 54.893 1.00 9.58 ? 429 ARG M CB 1 ATOM 3469 C CG . ARG A 1 429 ? 41.286 132.652 55.735 1.00 9.94 ? 429 ARG M CG 1 ATOM 3470 C CD . ARG A 1 429 ? 42.533 132.391 56.567 1.00 8.23 ? 429 ARG M CD 1 ATOM 3471 N NE . ARG A 1 429 ? 43.704 132.230 55.773 1.00 10.87 ? 429 ARG M NE 1 ATOM 3472 C CZ . ARG A 1 429 ? 44.709 133.077 55.606 1.00 11.38 ? 429 ARG M CZ 1 ATOM 3473 N NH1 . ARG A 1 429 ? 44.774 134.238 56.256 1.00 12.75 ? 429 ARG M NH1 1 ATOM 3474 N NH2 . ARG A 1 429 ? 45.699 132.685 54.865 1.00 12.40 ? 429 ARG M NH2 1 ATOM 3475 N N . ILE A 1 430 ? 38.305 134.960 54.909 1.00 9.90 ? 430 ILE M N 1 ATOM 3476 C CA . ILE A 1 430 ? 36.875 134.975 55.246 1.00 10.24 ? 430 ILE M CA 1 ATOM 3477 C C . ILE A 1 430 ? 36.017 134.523 54.081 1.00 11.13 ? 430 ILE M C 1 ATOM 3478 O O . ILE A 1 430 ? 35.172 133.625 54.250 1.00 10.52 ? 430 ILE M O 1 ATOM 3479 C CB . ILE A 1 430 ? 36.358 136.319 55.789 1.00 9.49 ? 430 ILE M CB 1 ATOM 3480 C CG1 . ILE A 1 430 ? 37.125 136.643 57.022 1.00 11.64 ? 430 ILE M CG1 1 ATOM 3481 C CG2 . ILE A 1 430 ? 34.886 136.295 55.994 1.00 12.23 ? 430 ILE M CG2 1 ATOM 3482 C CD1 . ILE A 1 430 ? 36.932 138.101 57.633 1.00 13.43 ? 430 ILE M CD1 1 ATOM 3483 N N . ASP A 1 431 ? 36.276 135.116 52.905 1.00 10.10 ? 431 ASP M N 1 ATOM 3484 C CA . ASP A 1 431 ? 35.485 134.814 51.722 1.00 9.69 ? 431 ASP M CA 1 ATOM 3485 C C . ASP A 1 431 ? 35.594 133.312 51.396 1.00 10.50 ? 431 ASP M C 1 ATOM 3486 O O . ASP A 1 431 ? 34.603 132.674 51.077 1.00 9.96 ? 431 ASP M O 1 ATOM 3487 C CB . ASP A 1 431 ? 35.883 135.640 50.588 1.00 10.71 ? 431 ASP M CB 1 ATOM 3488 C CG . ASP A 1 431 ? 35.358 137.138 50.736 1.00 14.76 ? 431 ASP M CG 1 ATOM 3489 O OD1 . ASP A 1 431 ? 34.497 137.391 51.679 1.00 18.03 ? 431 ASP M OD1 1 ATOM 3490 O OD2 . ASP A 1 431 ? 35.752 137.963 49.913 1.00 18.60 ? 431 ASP M OD2 1 ATOM 3491 N N . TYR A 1 432 ? 36.804 132.790 51.422 1.00 8.78 ? 432 TYR M N 1 ATOM 3492 C CA . TYR A 1 432 ? 37.003 131.357 51.107 1.00 7.84 ? 432 TYR M CA 1 ATOM 3493 C C . TYR A 1 432 ? 36.286 130.496 52.120 1.00 6.61 ? 432 TYR M C 1 ATOM 3494 O O . TYR A 1 432 ? 35.539 129.640 51.747 1.00 8.32 ? 432 TYR M O 1 ATOM 3495 C CB . TYR A 1 432 ? 38.494 131.052 51.100 1.00 6.56 ? 432 TYR M CB 1 ATOM 3496 C CG . TYR A 1 432 ? 38.771 129.596 50.756 1.00 6.53 ? 432 TYR M CG 1 ATOM 3497 C CD1 . TYR A 1 432 ? 38.773 128.636 51.762 1.00 7.08 ? 432 TYR M CD1 1 ATOM 3498 C CD2 . TYR A 1 432 ? 39.026 129.174 49.496 1.00 7.91 ? 432 TYR M CD2 1 ATOM 3499 C CE1 . TYR A 1 432 ? 39.036 127.339 51.468 1.00 6.87 ? 432 TYR M CE1 1 ATOM 3500 C CE2 . TYR A 1 432 ? 39.282 127.829 49.213 1.00 8.81 ? 432 TYR M CE2 1 ATOM 3501 C CZ . TYR A 1 432 ? 39.262 126.937 50.227 1.00 7.88 ? 432 TYR M CZ 1 ATOM 3502 O OH . TYR A 1 432 ? 39.517 125.612 49.952 1.00 8.74 ? 432 TYR M OH 1 ATOM 3503 N N . LEU A 1 433 ? 36.540 130.716 53.382 1.00 8.10 ? 433 LEU M N 1 ATOM 3504 C CA . LEU A 1 433 ? 35.973 129.854 54.417 1.00 8.74 ? 433 LEU M CA 1 ATOM 3505 C C . LEU A 1 433 ? 34.458 129.938 54.432 1.00 10.03 ? 433 LEU M C 1 ATOM 3506 O O . LEU A 1 433 ? 33.791 128.880 54.450 1.00 10.05 ? 433 LEU M O 1 ATOM 3507 C CB . LEU A 1 433 ? 36.538 130.175 55.748 1.00 7.80 ? 433 LEU M CB 1 ATOM 3508 C CG . LEU A 1 433 ? 38.033 129.933 55.988 1.00 7.77 ? 433 LEU M CG 1 ATOM 3509 C CD1 . LEU A 1 433 ? 38.455 130.624 57.310 1.00 9.87 ? 433 LEU M CD1 1 ATOM 3510 C CD2 . LEU A 1 433 ? 38.447 128.376 55.835 1.00 11.50 ? 433 LEU M CD2 1 ATOM 3511 N N . CYS A 1 434 ? 33.880 131.153 54.393 1.00 9.14 ? 434 CYS M N 1 ATOM 3512 C CA . CYS A 1 434 ? 32.404 131.265 54.423 1.00 9.13 ? 434 CYS M CA 1 ATOM 3513 C C . CYS A 1 434 ? 31.713 130.697 53.235 1.00 10.00 ? 434 CYS M C 1 ATOM 3514 O O . CYS A 1 434 ? 30.694 130.084 53.370 1.00 10.09 ? 434 CYS M O 1 ATOM 3515 C CB . CYS A 1 434 ? 31.987 132.694 54.662 1.00 10.95 ? 434 CYS M CB 1 ATOM 3516 S SG . CYS A 1 434 ? 32.052 133.902 53.446 1.00 15.75 ? 434 CYS M SG 1 ATOM 3517 N N . SER A 1 435 ? 32.358 130.833 52.057 1.00 11.33 ? 435 SER M N 1 ATOM 3518 C CA . SER A 1 435 ? 31.739 130.376 50.846 1.00 9.55 ? 435 SER M CA 1 ATOM 3519 C C . SER A 1 435 ? 31.624 128.837 50.799 1.00 9.44 ? 435 SER M C 1 ATOM 3520 O O . SER A 1 435 ? 30.654 128.214 50.358 1.00 11.01 ? 435 SER M O 1 ATOM 3521 C CB . SER A 1 435 ? 32.364 130.928 49.624 1.00 8.48 ? 435 SER M CB 1 ATOM 3522 O OG . SER A 1 435 ? 33.741 130.509 49.475 1.00 10.12 ? 435 SER M OG 1 ATOM 3523 N N . HIS A 1 436 ? 32.669 128.186 51.326 1.00 8.79 ? 436 HIS M N 1 ATOM 3524 C CA . HIS A 1 436 ? 32.697 126.760 51.478 1.00 8.07 ? 436 HIS M CA 1 ATOM 3525 C C . HIS A 1 436 ? 31.771 126.269 52.594 1.00 8.03 ? 436 HIS M C 1 ATOM 3526 O O . HIS A 1 436 ? 31.094 125.281 52.380 1.00 9.36 ? 436 HIS M O 1 ATOM 3527 C CB . HIS A 1 436 ? 34.143 126.272 51.698 1.00 8.54 ? 436 HIS M CB 1 ATOM 3528 C CG . HIS A 1 436 ? 34.981 126.332 50.489 1.00 8.05 ? 436 HIS M CG 1 ATOM 3529 N ND1 . HIS A 1 436 ? 35.516 127.504 50.057 1.00 9.24 ? 436 HIS M ND1 1 ATOM 3530 C CD2 . HIS A 1 436 ? 35.239 125.403 49.523 1.00 8.17 ? 436 HIS M CD2 1 ATOM 3531 C CE1 . HIS A 1 436 ? 36.127 127.275 48.897 1.00 9.38 ? 436 HIS M CE1 1 ATOM 3532 N NE2 . HIS A 1 436 ? 35.947 125.996 48.522 1.00 8.63 ? 436 HIS M NE2 1 ATOM 3533 N N . LEU A 1 437 ? 31.709 126.967 53.737 1.00 8.51 ? 437 LEU M N 1 ATOM 3534 C CA . LEU A 1 437 ? 30.767 126.570 54.798 1.00 7.89 ? 437 LEU M CA 1 ATOM 3535 C C . LEU A 1 437 ? 29.339 126.770 54.296 1.00 7.97 ? 437 LEU M C 1 ATOM 3536 O O . LEU A 1 437 ? 28.466 125.932 54.662 1.00 10.08 ? 437 LEU M O 1 ATOM 3537 C CB . LEU A 1 437 ? 31.039 127.413 56.013 1.00 8.75 ? 437 LEU M CB 1 ATOM 3538 C CG . LEU A 1 437 ? 32.215 126.918 56.803 1.00 10.16 ? 437 LEU M CG 1 ATOM 3539 C CD1 . LEU A 1 437 ? 32.736 128.002 57.800 1.00 12.18 ? 437 LEU M CD1 1 ATOM 3540 C CD2 . LEU A 1 437 ? 31.913 125.542 57.542 1.00 10.55 ? 437 LEU M CD2 1 ATOM 3541 N N . CYS A 1 438 ? 29.025 127.753 53.491 1.00 10.37 ? 438 CYS M N 1 ATOM 3542 C CA . CYS A 1 438 ? 27.661 127.894 52.951 1.00 9.42 ? 438 CYS M CA 1 ATOM 3543 C C . CYS A 1 438 ? 27.287 126.663 52.121 1.00 9.31 ? 438 CYS M C 1 ATOM 3544 O O . CYS A 1 438 ? 26.235 126.088 52.369 1.00 9.41 ? 438 CYS M O 1 ATOM 3545 C CB . CYS A 1 438 ? 27.624 129.014 52.000 1.00 10.39 ? 438 CYS M CB 1 ATOM 3546 S SG . CYS A 1 438 ? 25.871 129.521 51.549 1.00 21.53 ? 438 CYS M SG 1 ATOM 3547 N N . PHE A 1 439 ? 28.224 126.205 51.228 1.00 10.12 ? 439 PHE M N 1 ATOM 3548 C CA . PHE A 1 439 ? 27.983 125.032 50.453 1.00 8.17 ? 439 PHE M CA 1 ATOM 3549 C C . PHE A 1 439 ? 27.917 123.776 51.271 1.00 9.15 ? 439 PHE M C 1 ATOM 3550 O O . PHE A 1 439 ? 27.223 122.820 50.873 1.00 9.69 ? 439 PHE M O 1 ATOM 3551 C CB . PHE A 1 439 ? 28.906 124.894 49.241 1.00 9.46 ? 439 PHE M CB 1 ATOM 3552 C CG . PHE A 1 439 ? 28.395 125.644 48.002 1.00 8.53 ? 439 PHE M CG 1 ATOM 3553 C CD1 . PHE A 1 439 ? 27.354 125.117 47.241 1.00 10.14 ? 439 PHE M CD1 1 ATOM 3554 C CD2 . PHE A 1 439 ? 29.018 126.788 47.561 1.00 9.99 ? 439 PHE M CD2 1 ATOM 3555 C CE1 . PHE A 1 439 ? 26.887 125.747 46.187 1.00 11.20 ? 439 PHE M CE1 1 ATOM 3556 C CE2 . PHE A 1 439 ? 28.581 127.408 46.428 1.00 12.47 ? 439 PHE M CE2 1 ATOM 3557 C CZ . PHE A 1 439 ? 27.538 126.813 45.709 1.00 12.03 ? 439 PHE M CZ 1 ATOM 3558 N N . LEU A 1 440 ? 28.703 123.715 52.306 1.00 8.25 ? 440 LEU M N 1 ATOM 3559 C CA . LEU A 1 440 ? 28.680 122.566 53.165 1.00 8.08 ? 440 LEU M CA 1 ATOM 3560 C C . LEU A 1 440 ? 27.341 122.402 53.880 1.00 9.46 ? 440 LEU M C 1 ATOM 3561 O O . LEU A 1 440 ? 26.799 121.336 53.950 1.00 11.22 ? 440 LEU M O 1 ATOM 3562 C CB . LEU A 1 440 ? 29.820 122.588 54.162 1.00 9.83 ? 440 LEU M CB 1 ATOM 3563 C CG . LEU A 1 440 ? 30.065 121.365 55.026 1.00 7.92 ? 440 LEU M CG 1 ATOM 3564 C CD1 . LEU A 1 440 ? 30.413 120.138 54.147 1.00 10.53 ? 440 LEU M CD1 1 ATOM 3565 C CD2 . LEU A 1 440 ? 31.165 121.601 56.035 1.00 11.71 ? 440 LEU M CD2 1 ATOM 3566 N N . ASN A 1 441 ? 26.822 123.470 54.460 1.00 9.97 ? 441 ASN M N 1 ATOM 3567 C CA . ASN A 1 441 ? 25.484 123.521 55.058 1.00 10.75 ? 441 ASN M CA 1 ATOM 3568 C C . ASN A 1 441 ? 24.468 123.059 54.002 1.00 11.07 ? 441 ASN M C 1 ATOM 3569 O O . ASN A 1 441 ? 23.535 122.257 54.257 1.00 12.10 ? 441 ASN M O 1 ATOM 3570 C CB . ASN A 1 441 ? 25.167 124.883 55.644 1.00 11.15 ? 441 ASN M CB 1 ATOM 3571 C CG . ASN A 1 441 ? 23.766 124.970 56.254 1.00 16.42 ? 441 ASN M CG 1 ATOM 3572 O OD1 . ASN A 1 441 ? 23.436 124.157 57.087 1.00 19.89 ? 441 ASN M OD1 1 ATOM 3573 N ND2 . ASN A 1 441 ? 23.000 125.919 55.814 1.00 19.31 ? 441 ASN M ND2 1 ATOM 3574 N N . LYS A 1 442 ? 24.566 123.611 52.807 1.00 10.30 ? 442 LYS M N 1 ATOM 3575 C CA . LYS A 1 442 ? 23.634 123.299 51.710 1.00 11.22 ? 442 LYS M CA 1 ATOM 3576 C C . LYS A 1 442 ? 23.613 121.845 51.381 1.00 13.99 ? 442 LYS M C 1 ATOM 3577 O O . LYS A 1 442 ? 22.568 121.188 51.195 1.00 12.19 ? 442 LYS M O 1 ATOM 3578 C CB . LYS A 1 442 ? 23.973 124.135 50.503 1.00 13.76 ? 442 LYS M CB 1 ATOM 3579 C CG . LYS A 1 442 ? 22.951 123.975 49.341 1.00 13.27 ? 442 LYS M CG 1 ATOM 3580 C CD . LYS A 1 442 ? 23.401 124.767 48.144 1.00 17.43 ? 442 LYS M CD 1 ATOM 3581 C CE . LYS A 1 442 ? 22.636 124.532 46.809 1.00 23.58 ? 442 LYS M CE 1 ATOM 3582 N NZ . LYS A 1 442 ? 21.307 125.210 46.976 1.00 23.72 ? 442 LYS M NZ 1 ATOM 3583 N N . VAL A 1 443 ? 24.816 121.203 51.302 1.00 10.26 ? 443 VAL M N 1 ATOM 3584 C CA . VAL A 1 443 ? 24.811 119.805 50.915 1.00 9.86 ? 443 VAL M CA 1 ATOM 3585 C C . VAL A 1 443 ? 24.299 118.908 52.064 1.00 10.42 ? 443 VAL M C 1 ATOM 3586 O O . VAL A 1 443 ? 23.680 117.827 51.819 1.00 12.54 ? 443 VAL M O 1 ATOM 3587 C CB . VAL A 1 443 ? 26.217 119.300 50.432 1.00 8.94 ? 443 VAL M CB 1 ATOM 3588 C CG1 . VAL A 1 443 ? 27.203 119.047 51.571 1.00 11.40 ? 443 VAL M CG1 1 ATOM 3589 C CG2 . VAL A 1 443 ? 26.077 118.091 49.519 1.00 10.36 ? 443 VAL M CG2 1 ATOM 3590 N N . ILE A 1 444 ? 24.578 119.255 53.278 1.00 10.63 ? 444 ILE M N 1 ATOM 3591 C CA . ILE A 1 444 ? 24.054 118.493 54.420 1.00 9.73 ? 444 ILE M CA 1 ATOM 3592 C C . ILE A 1 444 ? 22.533 118.577 54.374 1.00 13.09 ? 444 ILE M C 1 ATOM 3593 O O . ILE A 1 444 ? 21.862 117.516 54.546 1.00 14.32 ? 444 ILE M O 1 ATOM 3594 C CB . ILE A 1 444 ? 24.599 119.004 55.695 1.00 9.92 ? 444 ILE M CB 1 ATOM 3595 C CG1 . ILE A 1 444 ? 26.098 118.765 55.830 1.00 9.76 ? 444 ILE M CG1 1 ATOM 3596 C CG2 . ILE A 1 444 ? 23.824 118.388 56.952 1.00 12.63 ? 444 ILE M CG2 1 ATOM 3597 C CD1 . ILE A 1 444 ? 26.776 119.642 56.915 1.00 10.86 ? 444 ILE M CD1 1 ATOM 3598 N N . LYS A 1 445 ? 22.000 119.754 54.148 1.00 14.02 ? 445 LYS M N 1 ATOM 3599 C CA . LYS A 1 445 ? 20.478 119.864 54.139 1.00 14.34 ? 445 LYS M CA 1 ATOM 3600 C C . LYS A 1 445 ? 19.814 119.285 52.941 1.00 17.56 ? 445 LYS M C 1 ATOM 3601 O O . LYS A 1 445 ? 18.766 118.649 53.067 1.00 18.62 ? 445 LYS M O 1 ATOM 3602 C CB . LYS A 1 445 ? 20.120 121.303 54.251 1.00 15.86 ? 445 LYS M CB 1 ATOM 3603 C CG . LYS A 1 445 ? 20.348 121.848 55.650 1.00 21.63 ? 445 LYS M CG 1 ATOM 3604 C CD . LYS A 1 445 ? 19.925 123.246 55.811 1.00 31.19 ? 445 LYS M CD 1 ATOM 3605 C CE . LYS A 1 445 ? 19.840 123.709 57.251 1.00 34.71 ? 445 LYS M CE 1 ATOM 3606 N NZ . LYS A 1 445 ? 20.868 123.393 58.238 1.00 32.23 ? 445 LYS M NZ 1 ATOM 3607 N N . GLU A 1 446 ? 20.401 119.402 51.770 1.00 14.12 ? 446 GLU M N 1 ATOM 3608 C CA . GLU A 1 446 ? 19.789 119.060 50.517 1.00 13.74 ? 446 GLU M CA 1 ATOM 3609 C C . GLU A 1 446 ? 19.982 117.600 50.195 1.00 15.79 ? 446 GLU M C 1 ATOM 3610 O O . GLU A 1 446 ? 19.168 116.980 49.542 1.00 16.96 ? 446 GLU M O 1 ATOM 3611 C CB . GLU A 1 446 ? 20.174 119.943 49.337 1.00 15.16 ? 446 GLU M CB 1 ATOM 3612 C CG . GLU A 1 446 ? 19.759 121.344 49.462 1.00 17.37 ? 446 GLU M CG 1 ATOM 3613 C CD . GLU A 1 446 ? 20.198 122.169 48.265 1.00 18.27 ? 446 GLU M CD 1 ATOM 3614 O OE1 . GLU A 1 446 ? 20.899 121.686 47.288 1.00 20.72 ? 446 GLU M OE1 1 ATOM 3615 O OE2 . GLU A 1 446 ? 19.767 123.321 48.235 1.00 21.92 ? 446 GLU M OE2 1 ATOM 3616 N N . LYS A 1 447 ? 21.162 117.049 50.501 1.00 13.07 ? 447 LYS M N 1 ATOM 3617 C CA . LYS A 1 447 ? 21.563 115.716 50.146 1.00 12.66 ? 447 LYS M CA 1 ATOM 3618 C C . LYS A 1 447 ? 21.664 114.798 51.297 1.00 11.82 ? 447 LYS M C 1 ATOM 3619 O O . LYS A 1 447 ? 21.916 113.596 51.113 1.00 13.45 ? 447 LYS M O 1 ATOM 3620 C CB . LYS A 1 447 ? 22.828 115.729 49.254 1.00 14.04 ? 447 LYS M CB 1 ATOM 3621 C CG . LYS A 1 447 ? 22.788 116.547 48.028 1.00 13.93 ? 447 LYS M CG 1 ATOM 3622 C CD . LYS A 1 447 ? 21.816 115.895 46.986 1.00 14.71 ? 447 LYS M CD 1 ATOM 3623 C CE . LYS A 1 447 ? 21.980 116.642 45.680 1.00 17.95 ? 447 LYS M CE 1 ATOM 3624 N NZ . LYS A 1 447 ? 20.949 115.923 44.751 1.00 23.35 ? 447 LYS M NZ 1 ATOM 3625 N N . ASP A 1 448 ? 21.563 115.301 52.489 1.00 12.11 ? 448 ASP M N 1 ATOM 3626 C CA . ASP A 1 448 ? 21.639 114.513 53.715 1.00 12.67 ? 448 ASP M CA 1 ATOM 3627 C C . ASP A 1 448 ? 22.966 113.717 53.898 1.00 14.36 ? 448 ASP M C 1 ATOM 3628 O O . ASP A 1 448 ? 23.035 112.562 54.295 1.00 14.80 ? 448 ASP M O 1 ATOM 3629 C CB . ASP A 1 448 ? 20.514 113.548 53.850 1.00 17.94 ? 448 ASP M CB 1 ATOM 3630 C CG . ASP A 1 448 ? 20.295 113.117 55.354 1.00 25.29 ? 448 ASP M CG 1 ATOM 3631 O OD1 . ASP A 1 448 ? 20.636 113.867 56.371 1.00 31.19 ? 448 ASP M OD1 1 ATOM 3632 O OD2 . ASP A 1 448 ? 19.750 111.971 55.466 1.00 33.33 ? 448 ASP M OD2 1 ATOM 3633 N N . VAL A 1 449 ? 24.066 114.383 53.449 1.00 12.49 ? 449 VAL M N 1 ATOM 3634 C CA . VAL A 1 449 ? 25.348 113.833 53.639 1.00 10.55 ? 449 VAL M CA 1 ATOM 3635 C C . VAL A 1 449 ? 25.671 113.854 55.105 1.00 9.94 ? 449 VAL M C 1 ATOM 3636 O O . VAL A 1 449 ? 25.362 114.844 55.832 1.00 10.97 ? 449 VAL M O 1 ATOM 3637 C CB A VAL A 1 449 ? 26.405 114.669 52.888 0.70 10.55 ? 449 VAL M CB 1 ATOM 3638 C CB B VAL A 1 449 ? 26.402 114.563 52.780 0.30 11.14 ? 449 VAL M CB 1 ATOM 3639 C CG1 A VAL A 1 449 ? 27.818 113.856 52.981 0.70 8.63 ? 449 VAL M CG1 1 ATOM 3640 C CG1 B VAL A 1 449 ? 26.205 114.183 51.204 0.30 4.85 ? 449 VAL M CG1 1 ATOM 3641 C CG2 A VAL A 1 449 ? 25.926 114.929 51.447 0.70 11.50 ? 449 VAL M CG2 1 ATOM 3642 C CG2 B VAL A 1 449 ? 26.414 116.056 53.135 0.30 12.88 ? 449 VAL M CG2 1 ATOM 3643 N N . ASN A 1 450 ? 26.251 112.763 55.625 1.00 9.42 ? 450 ASN M N 1 ATOM 3644 C CA . ASN A 1 450 ? 26.507 112.606 57.058 1.00 10.14 ? 450 ASN M CA 1 ATOM 3645 C C . ASN A 1 450 ? 27.838 113.251 57.463 1.00 8.91 ? 450 ASN M C 1 ATOM 3646 O O . ASN A 1 450 ? 28.801 112.575 57.876 1.00 10.84 ? 450 ASN M O 1 ATOM 3647 C CB . ASN A 1 450 ? 26.496 111.150 57.457 1.00 9.84 ? 450 ASN M CB 1 ATOM 3648 C CG . ASN A 1 450 ? 26.498 110.933 58.979 1.00 11.27 ? 450 ASN M CG 1 ATOM 3649 O OD1 . ASN A 1 450 ? 26.271 111.853 59.756 1.00 13.33 ? 450 ASN M OD1 1 ATOM 3650 N ND2 . ASN A 1 450 ? 26.754 109.694 59.371 1.00 12.06 ? 450 ASN M ND2 1 ATOM 3651 N N . VAL A 1 451 ? 27.895 114.574 57.353 1.00 10.11 ? 451 VAL M N 1 ATOM 3652 C CA . VAL A 1 451 ? 29.076 115.370 57.812 1.00 9.48 ? 451 VAL M CA 1 ATOM 3653 C C . VAL A 1 451 ? 28.797 115.861 59.166 1.00 10.64 ? 451 VAL M C 1 ATOM 3654 O O . VAL A 1 451 ? 27.706 116.430 59.473 1.00 11.94 ? 451 VAL M O 1 ATOM 3655 C CB . VAL A 1 451 ? 29.285 116.525 56.891 1.00 9.96 ? 451 VAL M CB 1 ATOM 3656 C CG1 . VAL A 1 451 ? 30.551 117.385 57.357 1.00 8.98 ? 451 VAL M CG1 1 ATOM 3657 C CG2 . VAL A 1 451 ? 29.416 116.127 55.362 1.00 11.37 ? 451 VAL M CG2 1 ATOM 3658 N N . LYS A 1 452 ? 29.749 115.633 60.097 1.00 9.30 ? 452 LYS M N 1 ATOM 3659 C CA . LYS A 1 452 ? 29.555 115.985 61.503 1.00 8.99 ? 452 LYS M CA 1 ATOM 3660 C C . LYS A 1 452 ? 30.551 116.973 62.086 1.00 9.77 ? 452 LYS M C 1 ATOM 3661 O O . LYS A 1 452 ? 30.471 117.310 63.265 1.00 9.78 ? 452 LYS M O 1 ATOM 3662 C CB . LYS A 1 452 ? 29.401 114.730 62.376 1.00 10.74 ? 452 LYS M CB 1 ATOM 3663 C CG . LYS A 1 452 ? 28.123 113.951 62.108 1.00 12.88 ? 452 LYS M CG 1 ATOM 3664 C CD . LYS A 1 452 ? 27.929 112.864 63.147 1.00 20.06 ? 452 LYS M CD 1 ATOM 3665 C CE . LYS A 1 452 ? 27.178 113.468 64.260 1.00 31.45 ? 452 LYS M CE 1 ATOM 3666 N NZ . LYS A 1 452 ? 25.774 113.521 63.706 1.00 34.34 ? 452 LYS M NZ 1 ATOM 3667 N N . GLY A 1 453 ? 31.511 117.453 61.280 1.00 8.89 ? 453 GLY M N 1 ATOM 3668 C CA . GLY A 1 453 ? 32.364 118.537 61.745 1.00 7.73 ? 453 GLY M CA 1 ATOM 3669 C C . GLY A 1 453 ? 33.204 119.067 60.605 1.00 8.86 ? 453 GLY M C 1 ATOM 3670 O O . GLY A 1 453 ? 33.253 118.470 59.531 1.00 8.91 ? 453 GLY M O 1 ATOM 3671 N N . TYR A 1 454 ? 33.866 120.155 60.950 1.00 8.54 ? 454 TYR M N 1 ATOM 3672 C CA . TYR A 1 454 ? 34.619 120.988 60.027 1.00 7.94 ? 454 TYR M CA 1 ATOM 3673 C C . TYR A 1 454 ? 35.803 121.597 60.807 1.00 7.60 ? 454 TYR M C 1 ATOM 3674 O O . TYR A 1 454 ? 35.613 122.300 61.833 1.00 8.81 ? 454 TYR M O 1 ATOM 3675 C CB . TYR A 1 454 ? 33.714 122.062 59.411 1.00 8.08 ? 454 TYR M CB 1 ATOM 3676 C CG . TYR A 1 454 ? 34.427 123.076 58.596 1.00 7.20 ? 454 TYR M CG 1 ATOM 3677 C CD1 . TYR A 1 454 ? 34.955 124.219 59.185 1.00 8.78 ? 454 TYR M CD1 1 ATOM 3678 C CD2 . TYR A 1 454 ? 34.575 122.934 57.213 1.00 7.30 ? 454 TYR M CD2 1 ATOM 3679 C CE1 . TYR A 1 454 ? 35.611 125.180 58.406 1.00 9.36 ? 454 TYR M CE1 1 ATOM 3680 C CE2 . TYR A 1 454 ? 35.259 123.894 56.427 1.00 7.89 ? 454 TYR M CE2 1 ATOM 3681 C CZ . TYR A 1 454 ? 35.732 125.020 57.063 1.00 9.18 ? 454 TYR M CZ 1 ATOM 3682 O OH . TYR A 1 454 ? 36.370 125.948 56.255 1.00 10.58 ? 454 TYR M OH 1 ATOM 3683 N N . LEU A 1 455 ? 36.994 121.372 60.240 1.00 8.35 ? 455 LEU M N 1 ATOM 3684 C CA . LEU A 1 455 ? 38.290 121.830 60.802 1.00 8.12 ? 455 LEU M CA 1 ATOM 3685 C C . LEU A 1 455 ? 39.063 122.586 59.626 1.00 11.51 ? 455 LEU M C 1 ATOM 3686 C CB . LEU A 1 455 ? 39.120 120.696 61.341 1.00 9.30 ? 455 LEU M CB 1 ATOM 3687 C CG . LEU A 1 455 ? 38.391 119.771 62.300 1.00 10.46 ? 455 LEU M CG 1 ATOM 3688 C CD1 . LEU A 1 455 ? 39.189 118.534 62.660 1.00 18.06 ? 455 LEU M CD1 1 ATOM 3689 C CD2 . LEU A 1 455 ? 38.017 120.417 63.672 1.00 14.22 ? 455 LEU M CD2 1 ATOM 3690 N N . ALA A 1 456 ? 39.074 123.910 59.928 1.00 7.94 ? 456 ALA M N 1 ATOM 3691 C CA . ALA A 1 456 ? 39.758 124.769 58.972 1.00 7.48 ? 456 ALA M CA 1 ATOM 3692 C C . ALA A 1 456 ? 41.250 124.614 59.108 1.00 10.02 ? 456 ALA M C 1 ATOM 3693 O O . ALA A 1 456 ? 41.811 124.499 60.201 1.00 9.86 ? 456 ALA M O 1 ATOM 3694 C CB . ALA A 1 456 ? 39.396 126.215 59.212 1.00 11.27 ? 456 ALA M CB 1 ATOM 3695 N N . TRP A 1 457 ? 41.960 124.666 57.977 1.00 8.52 ? 457 TRP M N 1 ATOM 3696 C CA . TRP A 1 457 ? 43.441 124.703 57.923 1.00 7.87 ? 457 TRP M CA 1 ATOM 3697 C C . TRP A 1 457 ? 43.785 126.197 57.840 1.00 10.57 ? 457 TRP M C 1 ATOM 3698 O O . TRP A 1 457 ? 43.320 126.828 56.913 1.00 11.74 ? 457 TRP M O 1 ATOM 3699 C CB . TRP A 1 457 ? 44.004 123.966 56.701 1.00 9.22 ? 457 TRP M CB 1 ATOM 3700 C CG . TRP A 1 457 ? 45.485 123.968 56.821 1.00 8.40 ? 457 TRP M CG 1 ATOM 3701 C CD1 . TRP A 1 457 ? 46.342 124.812 56.201 1.00 11.36 ? 457 TRP M CD1 1 ATOM 3702 C CD2 . TRP A 1 457 ? 46.262 123.026 57.501 1.00 8.91 ? 457 TRP M CD2 1 ATOM 3703 N NE1 . TRP A 1 457 ? 47.635 124.506 56.542 1.00 11.99 ? 457 TRP M NE1 1 ATOM 3704 C CE2 . TRP A 1 457 ? 47.620 123.421 57.371 1.00 10.87 ? 457 TRP M CE2 1 ATOM 3705 C CE3 . TRP A 1 457 ? 45.940 121.901 58.290 1.00 9.52 ? 457 TRP M CE3 1 ATOM 3706 C CZ2 . TRP A 1 457 ? 48.638 122.747 58.032 1.00 10.63 ? 457 TRP M CZ2 1 ATOM 3707 C CZ3 . TRP A 1 457 ? 46.984 121.236 58.901 1.00 11.05 ? 457 TRP M CZ3 1 ATOM 3708 C CH2 . TRP A 1 457 ? 48.308 121.650 58.732 1.00 10.39 ? 457 TRP M CH2 1 ATOM 3709 N N . ALA A 1 458 ? 44.557 126.801 58.758 1.00 7.86 ? 458 ALA M N 1 ATOM 3710 C CA . ALA A 1 458 ? 45.214 126.217 59.895 1.00 7.96 ? 458 ALA M CA 1 ATOM 3711 C C . ALA A 1 458 ? 44.978 127.100 61.083 1.00 8.24 ? 458 ALA M C 1 ATOM 3712 O O . ALA A 1 458 ? 44.612 128.258 60.986 1.00 9.56 ? 458 ALA M O 1 ATOM 3713 C CB . ALA A 1 458 ? 46.743 126.168 59.652 1.00 9.51 ? 458 ALA M CB 1 ATOM 3714 N N . LEU A 1 459 ? 45.219 126.555 62.272 1.00 9.32 ? 459 LEU M N 1 ATOM 3715 C CA . LEU A 1 459 ? 45.186 127.296 63.534 1.00 8.16 ? 459 LEU M CA 1 ATOM 3716 C C . LEU A 1 459 ? 45.961 128.601 63.432 1.00 11.58 ? 459 LEU M C 1 ATOM 3717 O O . LEU A 1 459 ? 45.476 129.646 63.803 1.00 12.85 ? 459 LEU M O 1 ATOM 3718 C CB . LEU A 1 459 ? 45.590 126.426 64.726 1.00 9.04 ? 459 LEU M CB 1 ATOM 3719 C CG . LEU A 1 459 ? 45.466 127.114 66.079 1.00 11.36 ? 459 LEU M CG 1 ATOM 3720 C CD1 . LEU A 1 459 ? 45.309 126.042 67.226 1.00 12.50 ? 459 LEU M CD1 1 ATOM 3721 C CD2 . LEU A 1 459 ? 46.809 127.999 66.423 1.00 14.11 ? 459 LEU M CD2 1 ATOM 3722 N N . GLY A 1 460 ? 47.184 128.456 62.993 1.00 11.08 ? 460 GLY M N 1 ATOM 3723 C CA . GLY A 1 460 ? 48.166 129.493 62.926 1.00 10.99 ? 460 GLY M CA 1 ATOM 3724 C C . GLY A 1 460 ? 49.047 129.347 61.734 1.00 10.91 ? 460 GLY M C 1 ATOM 3725 O O . GLY A 1 460 ? 49.070 128.346 61.055 1.00 11.93 ? 460 GLY M O 1 ATOM 3726 N N . ASP A 1 461 ? 49.763 130.419 61.366 1.00 11.77 ? 461 ASP M N 1 ATOM 3727 C CA . ASP A 1 461 ? 50.776 130.334 60.372 1.00 10.26 ? 461 ASP M CA 1 ATOM 3728 C C . ASP A 1 461 ? 51.840 129.340 60.811 1.00 10.88 ? 461 ASP M C 1 ATOM 3729 O O . ASP A 1 461 ? 52.173 129.181 61.973 1.00 14.16 ? 461 ASP M O 1 ATOM 3730 C CB . ASP A 1 461 ? 51.383 131.731 60.129 1.00 10.88 ? 461 ASP M CB 1 ATOM 3731 C CG . ASP A 1 461 ? 50.328 132.721 59.712 1.00 13.83 ? 461 ASP M CG 1 ATOM 3732 O OD1 . ASP A 1 461 ? 49.338 132.314 59.032 1.00 11.03 ? 461 ASP M OD1 1 ATOM 3733 O OD2 . ASP A 1 461 ? 50.476 133.959 60.036 1.00 13.35 ? 461 ASP M OD2 1 ATOM 3734 N N . ASN A 1 462 ? 52.304 128.600 59.810 1.00 11.27 ? 462 ASN M N 1 ATOM 3735 C CA . ASN A 1 462 ? 53.249 127.498 60.077 1.00 10.67 ? 462 ASN M CA 1 ATOM 3736 C C . ASN A 1 462 ? 54.129 127.249 58.874 1.00 11.78 ? 462 ASN M C 1 ATOM 3737 O O . ASN A 1 462 ? 54.074 127.965 57.860 1.00 11.63 ? 462 ASN M O 1 ATOM 3738 C CB . ASN A 1 462 ? 52.488 126.268 60.557 1.00 12.83 ? 462 ASN M CB 1 ATOM 3739 C CG . ASN A 1 462 ? 51.480 125.782 59.628 1.00 16.05 ? 462 ASN M CG 1 ATOM 3740 O OD1 . ASN A 1 462 ? 51.731 125.562 58.505 1.00 17.66 ? 462 ASN M OD1 1 ATOM 3741 N ND2 . ASN A 1 462 ? 50.303 125.428 60.193 1.00 19.93 ? 462 ASN M ND2 1 ATOM 3742 N N . TYR A 1 463 ? 55.016 126.260 58.961 1.00 10.53 ? 463 TYR M N 1 ATOM 3743 C CA . TYR A 1 463 ? 55.831 125.845 57.805 1.00 10.37 ? 463 TYR M CA 1 ATOM 3744 C C . TYR A 1 463 ? 54.877 125.114 56.880 1.00 10.51 ? 463 TYR M C 1 ATOM 3745 O O . TYR A 1 463 ? 54.205 124.176 57.306 1.00 11.64 ? 463 TYR M O 1 ATOM 3746 C CB . TYR A 1 463 ? 56.960 124.888 58.217 1.00 10.67 ? 463 TYR M CB 1 ATOM 3747 C CG . TYR A 1 463 ? 57.585 124.208 57.070 1.00 8.99 ? 463 TYR M CG 1 ATOM 3748 C CD1 . TYR A 1 463 ? 58.514 124.815 56.255 1.00 10.45 ? 463 TYR M CD1 1 ATOM 3749 C CD2 . TYR A 1 463 ? 57.179 122.956 56.684 1.00 7.58 ? 463 TYR M CD2 1 ATOM 3750 C CE1 . TYR A 1 463 ? 58.986 124.225 55.119 1.00 10.89 ? 463 TYR M CE1 1 ATOM 3751 C CE2 . TYR A 1 463 ? 57.652 122.313 55.579 1.00 7.91 ? 463 TYR M CE2 1 ATOM 3752 C CZ . TYR A 1 463 ? 58.535 122.975 54.754 1.00 9.48 ? 463 TYR M CZ 1 ATOM 3753 O OH . TYR A 1 463 ? 58.946 122.363 53.589 1.00 10.58 ? 463 TYR M OH 1 ATOM 3754 N N . GLU A 1 464 ? 54.739 125.518 55.639 1.00 9.11 ? 464 GLU M N 1 ATOM 3755 C CA . GLU A 1 464 ? 53.946 124.806 54.679 1.00 8.72 ? 464 GLU M CA 1 ATOM 3756 C C . GLU A 1 464 ? 54.862 123.945 53.780 1.00 10.92 ? 464 GLU M C 1 ATOM 3757 O O . GLU A 1 464 ? 55.842 124.437 53.161 1.00 10.67 ? 464 GLU M O 1 ATOM 3758 C CB . GLU A 1 464 ? 53.168 125.749 53.795 1.00 11.11 ? 464 GLU M CB 1 ATOM 3759 C CG . GLU A 1 464 ? 52.374 125.128 52.650 1.00 13.54 ? 464 GLU M CG 1 ATOM 3760 C CD . GLU A 1 464 ? 51.315 124.120 53.148 1.00 19.89 ? 464 GLU M CD 1 ATOM 3761 O OE1 . GLU A 1 464 ? 50.941 124.061 54.371 1.00 19.09 ? 464 GLU M OE1 1 ATOM 3762 O OE2 . GLU A 1 464 ? 50.793 123.399 52.191 1.00 25.60 ? 464 GLU M OE2 1 ATOM 3763 N N . PHE A 1 465 ? 54.546 122.669 53.662 1.00 10.08 ? 465 PHE M N 1 ATOM 3764 C CA . PHE A 1 465 ? 55.317 121.705 52.854 1.00 9.17 ? 465 PHE M CA 1 ATOM 3765 C C . PHE A 1 465 ? 55.582 122.248 51.465 1.00 12.95 ? 465 PHE M C 1 ATOM 3766 O O . PHE A 1 465 ? 54.628 122.809 50.838 1.00 15.12 ? 465 PHE M O 1 ATOM 3767 C CB . PHE A 1 465 ? 54.614 120.332 52.820 1.00 9.88 ? 465 PHE M CB 1 ATOM 3768 C CG . PHE A 1 465 ? 54.416 119.701 54.114 1.00 10.58 ? 465 PHE M CG 1 ATOM 3769 C CD1 . PHE A 1 465 ? 55.492 119.132 54.769 1.00 9.34 ? 465 PHE M CD1 1 ATOM 3770 C CD2 . PHE A 1 465 ? 53.129 119.624 54.681 1.00 14.32 ? 465 PHE M CD2 1 ATOM 3771 C CE1 . PHE A 1 465 ? 55.349 118.452 55.895 1.00 10.74 ? 465 PHE M CE1 1 ATOM 3772 C CE2 . PHE A 1 465 ? 52.983 118.948 55.875 1.00 11.06 ? 465 PHE M CE2 1 ATOM 3773 C CZ . PHE A 1 465 ? 54.073 118.321 56.477 1.00 10.26 ? 465 PHE M CZ 1 ATOM 3774 N N . ASN A 1 466 ? 56.847 122.257 51.140 1.00 13.43 ? 466 ASN M N 1 ATOM 3775 C CA A ASN A 1 466 ? 57.181 122.792 49.754 0.50 13.96 ? 466 ASN M CA 1 ATOM 3776 C CA B ASN A 1 466 ? 57.477 122.733 49.923 0.50 14.03 ? 466 ASN M CA 1 ATOM 3777 C C . ASN A 1 466 ? 57.334 124.228 49.619 1.00 16.03 ? 466 ASN M C 1 ATOM 3778 O O . ASN A 1 466 ? 57.912 124.647 48.603 1.00 17.07 ? 466 ASN M O 1 ATOM 3779 C CB A ASN A 1 466 ? 56.105 122.483 48.648 0.50 14.41 ? 466 ASN M CB 1 ATOM 3780 C CB B ASN A 1 466 ? 57.262 121.712 48.763 0.50 13.72 ? 466 ASN M CB 1 ATOM 3781 C CG A ASN A 1 466 ? 55.767 121.048 48.565 0.50 20.02 ? 466 ASN M CG 1 ATOM 3782 C CG B ASN A 1 466 ? 55.877 121.752 48.178 0.50 16.01 ? 466 ASN M CG 1 ATOM 3783 O OD1 A ASN A 1 466 ? 54.582 120.686 48.500 0.50 22.48 ? 466 ASN M OD1 1 ATOM 3784 O OD1 B ASN A 1 466 ? 55.177 120.733 48.168 0.50 27.60 ? 466 ASN M OD1 1 ATOM 3785 N ND2 A ASN A 1 466 ? 56.774 120.213 48.677 0.50 16.47 ? 466 ASN M ND2 1 ATOM 3786 N ND2 B ASN A 1 466 ? 55.470 122.879 47.704 0.50 13.67 ? 466 ASN M ND2 1 ATOM 3787 N N . LYS A 1 467 ? 56.745 125.019 50.510 1.00 12.84 ? 467 LYS M N 1 ATOM 3788 C CA . LYS A 1 467 ? 56.581 126.448 50.400 1.00 13.86 ? 467 LYS M CA 1 ATOM 3789 C C . LYS A 1 467 ? 57.289 127.240 51.431 1.00 12.34 ? 467 LYS M C 1 ATOM 3790 O O . LYS A 1 467 ? 57.337 128.435 51.459 1.00 12.81 ? 467 LYS M O 1 ATOM 3791 C CB . LYS A 1 467 ? 55.112 126.828 50.384 1.00 15.36 ? 467 LYS M CB 1 ATOM 3792 C CG . LYS A 1 467 ? 54.281 126.186 49.308 1.00 23.99 ? 467 LYS M CG 1 ATOM 3793 C CD . LYS A 1 467 ? 54.828 126.462 48.014 1.00 34.78 ? 467 LYS M CD 1 ATOM 3794 C CE . LYS A 1 467 ? 53.789 126.051 46.920 1.00 41.40 ? 467 LYS M CE 1 ATOM 3795 N NZ . LYS A 1 467 ? 52.485 126.704 47.204 1.00 43.86 ? 467 LYS M NZ 1 ATOM 3796 N N . GLY A 1 468 ? 57.871 126.558 52.460 1.00 12.46 ? 468 GLY M N 1 ATOM 3797 C CA . GLY A 1 468 ? 58.553 127.293 53.521 1.00 11.76 ? 468 GLY M CA 1 ATOM 3798 C C . GLY A 1 468 ? 57.630 128.160 54.284 1.00 12.63 ? 468 GLY M C 1 ATOM 3799 O O . GLY A 1 468 ? 56.509 127.751 54.634 1.00 15.16 ? 468 GLY M O 1 ATOM 3800 N N . PHE A 1 469 ? 58.011 129.411 54.490 1.00 12.59 ? 469 PHE M N 1 ATOM 3801 C CA . PHE A 1 469 ? 57.224 130.425 55.126 1.00 9.69 ? 469 PHE M CA 1 ATOM 3802 C C . PHE A 1 469 ? 56.701 131.492 54.061 1.00 12.15 ? 469 PHE M C 1 ATOM 3803 O O . PHE A 1 469 ? 56.323 132.585 54.468 1.00 16.01 ? 469 PHE M O 1 ATOM 3804 C CB . PHE A 1 469 ? 57.950 131.045 56.323 1.00 12.42 ? 469 PHE M CB 1 ATOM 3805 C CG . PHE A 1 469 ? 58.317 130.029 57.370 1.00 11.13 ? 469 PHE M CG 1 ATOM 3806 C CD1 . PHE A 1 469 ? 57.419 129.588 58.333 1.00 10.62 ? 469 PHE M CD1 1 ATOM 3807 C CD2 . PHE A 1 469 ? 59.532 129.370 57.266 1.00 12.05 ? 469 PHE M CD2 1 ATOM 3808 C CE1 . PHE A 1 469 ? 57.771 128.533 59.206 1.00 12.34 ? 469 PHE M CE1 1 ATOM 3809 C CE2 . PHE A 1 469 ? 59.888 128.351 58.127 1.00 11.54 ? 469 PHE M CE2 1 ATOM 3810 C CZ . PHE A 1 469 ? 59.008 127.934 59.074 1.00 10.58 ? 469 PHE M CZ 1 ATOM 3811 N N . THR A 1 470 ? 56.746 131.080 52.816 1.00 13.51 ? 470 THR M N 1 ATOM 3812 C CA . THR A 1 470 ? 56.322 131.984 51.709 1.00 15.61 ? 470 THR M CA 1 ATOM 3813 C C . THR A 1 470 ? 54.816 132.154 51.572 1.00 17.01 ? 470 THR M C 1 ATOM 3814 O O . THR A 1 470 ? 54.384 132.984 50.796 1.00 17.95 ? 470 THR M O 1 ATOM 3815 C CB . THR A 1 470 ? 56.886 131.578 50.369 1.00 13.54 ? 470 THR M CB 1 ATOM 3816 O OG1 . THR A 1 470 ? 56.365 130.374 49.868 1.00 15.24 ? 470 THR M OG1 1 ATOM 3817 C CG2 . THR A 1 470 ? 58.436 131.522 50.527 1.00 17.03 ? 470 THR M CG2 1 ATOM 3818 N N . VAL A 1 471 ? 54.049 131.296 52.243 1.00 14.41 ? 471 VAL M N 1 ATOM 3819 C CA . VAL A 1 471 ? 52.592 131.406 52.290 1.00 14.57 ? 471 VAL M CA 1 ATOM 3820 C C . VAL A 1 471 ? 52.176 131.297 53.735 1.00 17.46 ? 471 VAL M C 1 ATOM 3821 O O . VAL A 1 471 ? 52.870 130.641 54.540 1.00 16.57 ? 471 VAL M O 1 ATOM 3822 C CB . VAL A 1 471 ? 51.887 130.454 51.411 1.00 15.42 ? 471 VAL M CB 1 ATOM 3823 C CG1 . VAL A 1 471 ? 52.205 130.640 49.917 1.00 19.45 ? 471 VAL M CG1 1 ATOM 3824 C CG2 . VAL A 1 471 ? 52.108 129.026 51.806 1.00 14.86 ? 471 VAL M CG2 1 ATOM 3825 N N . ARG A 1 472 ? 51.090 131.959 54.071 1.00 11.43 ? 472 ARG M N 1 ATOM 3826 C CA . ARG A 1 472 ? 50.471 131.896 55.396 1.00 12.42 ? 472 ARG M CA 1 ATOM 3827 C C . ARG A 1 472 ? 49.119 131.298 55.263 1.00 12.99 ? 472 ARG M C 1 ATOM 3828 O O . ARG A 1 472 ? 48.379 131.766 54.416 1.00 12.83 ? 472 ARG M O 1 ATOM 3829 C CB . ARG A 1 472 ? 50.328 133.272 56.007 1.00 11.15 ? 472 ARG M CB 1 ATOM 3830 C CG . ARG A 1 472 ? 51.669 133.870 56.379 1.00 14.58 ? 472 ARG M CG 1 ATOM 3831 C CD . ARG A 1 472 ? 51.473 135.200 57.068 1.00 14.14 ? 472 ARG M CD 1 ATOM 3832 N NE . ARG A 1 472 ? 52.729 135.922 57.310 1.00 14.79 ? 472 ARG M NE 1 ATOM 3833 C CZ . ARG A 1 472 ? 53.412 135.790 58.443 1.00 17.20 ? 472 ARG M CZ 1 ATOM 3834 N NH1 . ARG A 1 472 ? 52.994 135.021 59.451 1.00 14.89 ? 472 ARG M NH1 1 ATOM 3835 N NH2 . ARG A 1 472 ? 54.591 136.452 58.541 1.00 19.34 ? 472 ARG M NH2 1 ATOM 3836 N N . PHE A 1 473 ? 48.747 130.261 56.040 1.00 10.17 ? 473 PHE M N 1 ATOM 3837 C CA . PHE A 1 473 ? 47.408 129.721 56.036 1.00 9.94 ? 473 PHE M CA 1 ATOM 3838 C C . PHE A 1 473 ? 46.658 129.950 57.322 1.00 9.81 ? 473 PHE M C 1 ATOM 3839 O O . PHE A 1 473 ? 45.504 129.507 57.459 1.00 10.70 ? 473 PHE M O 1 ATOM 3840 C CB . PHE A 1 473 ? 47.480 128.221 55.810 1.00 10.48 ? 473 PHE M CB 1 ATOM 3841 C CG . PHE A 1 473 ? 47.576 127.742 54.382 1.00 8.56 ? 473 PHE M CG 1 ATOM 3842 C CD1 . PHE A 1 473 ? 46.409 127.446 53.650 1.00 10.15 ? 473 PHE M CD1 1 ATOM 3843 C CD2 . PHE A 1 473 ? 48.808 127.502 53.758 1.00 13.18 ? 473 PHE M CD2 1 ATOM 3844 C CE1 . PHE A 1 473 ? 46.509 127.001 52.336 1.00 12.62 ? 473 PHE M CE1 1 ATOM 3845 C CE2 . PHE A 1 473 ? 48.845 127.043 52.471 1.00 13.56 ? 473 PHE M CE2 1 ATOM 3846 C CZ . PHE A 1 473 ? 47.719 126.817 51.768 1.00 11.09 ? 473 PHE M CZ 1 ATOM 3847 N N . GLY A 1 474 ? 47.246 130.560 58.346 1.00 9.67 ? 474 GLY M N 1 ATOM 3848 C CA . GLY A 1 474 ? 46.637 130.624 59.678 1.00 10.37 ? 474 GLY M CA 1 ATOM 3849 C C . GLY A 1 474 ? 45.415 131.498 59.765 1.00 9.74 ? 474 GLY M C 1 ATOM 3850 O O . GLY A 1 474 ? 45.264 132.514 59.051 1.00 11.53 ? 474 GLY M O 1 ATOM 3851 N N . LEU A 1 475 ? 44.504 131.133 60.663 1.00 9.84 ? 475 LEU M N 1 ATOM 3852 C CA . LEU A 1 475 ? 43.461 132.007 61.147 1.00 9.17 ? 475 LEU M CA 1 ATOM 3853 C C . LEU A 1 475 ? 44.072 132.992 62.181 1.00 11.95 ? 475 LEU M C 1 ATOM 3854 O O . LEU A 1 475 ? 43.406 133.978 62.563 1.00 12.04 ? 475 LEU M O 1 ATOM 3855 C CB . LEU A 1 475 ? 42.249 131.241 61.688 1.00 10.68 ? 475 LEU M CB 1 ATOM 3856 C CG . LEU A 1 475 ? 41.297 130.799 60.569 1.00 11.92 ? 475 LEU M CG 1 ATOM 3857 C CD1 . LEU A 1 475 ? 41.889 129.712 59.570 1.00 11.83 ? 475 LEU M CD1 1 ATOM 3858 C CD2 . LEU A 1 475 ? 39.934 130.306 61.159 1.00 15.51 ? 475 LEU M CD2 1 ATOM 3859 N N . SER A 1 476 ? 45.233 132.628 62.733 1.00 11.23 ? 476 SER M N 1 ATOM 3860 C CA . SER A 1 476 ? 46.015 133.475 63.702 1.00 13.11 ? 476 SER M CA 1 ATOM 3861 C C . SER A 1 476 ? 47.384 133.661 63.061 1.00 12.94 ? 476 SER M C 1 ATOM 3862 O O . SER A 1 476 ? 47.936 132.822 62.387 1.00 12.68 ? 476 SER M O 1 ATOM 3863 C CB . SER A 1 476 ? 46.032 132.867 65.094 1.00 12.63 ? 476 SER M CB 1 ATOM 3864 O OG . SER A 1 476 ? 46.703 131.664 65.112 1.00 14.05 ? 476 SER M OG 1 ATOM 3865 N N . TYR A 1 477 ? 47.947 134.872 63.294 1.00 13.71 ? 477 TYR M N 1 ATOM 3866 C CA . TYR A 1 477 ? 49.159 135.312 62.795 1.00 13.77 ? 477 TYR M CA 1 ATOM 3867 C C . TYR A 1 477 ? 50.324 135.066 63.741 1.00 14.06 ? 477 TYR M C 1 ATOM 3868 O O . TYR A 1 477 ? 50.190 135.254 64.940 1.00 15.79 ? 477 TYR M O 1 ATOM 3869 C CB . TYR A 1 477 ? 49.097 136.860 62.544 1.00 13.60 ? 477 TYR M CB 1 ATOM 3870 C CG . TYR A 1 477 ? 50.347 137.469 61.978 1.00 13.97 ? 477 TYR M CG 1 ATOM 3871 C CD1 . TYR A 1 477 ? 50.582 137.556 60.626 1.00 17.86 ? 477 TYR M CD1 1 ATOM 3872 C CD2 . TYR A 1 477 ? 51.301 138.001 62.843 1.00 20.72 ? 477 TYR M CD2 1 ATOM 3873 C CE1 . TYR A 1 477 ? 51.749 138.098 60.102 1.00 20.37 ? 477 TYR M CE1 1 ATOM 3874 C CE2 . TYR A 1 477 ? 52.462 138.596 62.288 1.00 17.53 ? 477 TYR M CE2 1 ATOM 3875 C CZ . TYR A 1 477 ? 52.658 138.622 60.978 1.00 20.71 ? 477 TYR M CZ 1 ATOM 3876 O OH . TYR A 1 477 ? 53.790 139.253 60.430 1.00 23.69 ? 477 TYR M OH 1 ATOM 3877 N N . ILE A 1 478 ? 51.430 134.605 63.142 1.00 13.86 ? 478 ILE M N 1 ATOM 3878 C CA . ILE A 1 478 ? 52.690 134.344 63.855 1.00 14.59 ? 478 ILE M CA 1 ATOM 3879 C C . ILE A 1 478 ? 53.773 135.228 63.246 1.00 13.97 ? 478 ILE M C 1 ATOM 3880 O O . ILE A 1 478 ? 54.048 135.172 62.005 1.00 16.27 ? 478 ILE M O 1 ATOM 3881 C CB . ILE A 1 478 ? 53.026 132.836 63.927 1.00 18.40 ? 478 ILE M CB 1 ATOM 3882 C CG1 . ILE A 1 478 ? 51.856 132.113 64.677 1.00 22.43 ? 478 ILE M CG1 1 ATOM 3883 C CG2 . ILE A 1 478 ? 54.508 132.629 64.618 1.00 20.29 ? 478 ILE M CG2 1 ATOM 3884 C CD1 . ILE A 1 478 ? 51.936 130.640 64.945 1.00 32.72 ? 478 ILE M CD1 1 ATOM 3885 N N . ASP A 1 479 ? 54.474 135.997 64.109 1.00 17.00 ? 479 ASP M N 1 ATOM 3886 C CA . ASP A 1 479 ? 55.635 136.807 63.690 1.00 17.93 ? 479 ASP M CA 1 ATOM 3887 C C . ASP A 1 479 ? 56.899 135.974 63.704 1.00 17.56 ? 479 ASP M C 1 ATOM 3888 O O . ASP A 1 479 ? 57.249 135.472 64.769 1.00 17.61 ? 479 ASP M O 1 ATOM 3889 C CB . ASP A 1 479 ? 55.802 137.909 64.750 1.00 19.22 ? 479 ASP M CB 1 ATOM 3890 C CG . ASP A 1 479 ? 56.992 138.789 64.495 1.00 25.33 ? 479 ASP M CG 1 ATOM 3891 O OD1 . ASP A 1 479 ? 57.798 138.572 63.623 1.00 24.05 ? 479 ASP M OD1 1 ATOM 3892 O OD2 . ASP A 1 479 ? 57.057 139.797 65.214 1.00 30.06 ? 479 ASP M OD2 1 ATOM 3893 N N . TRP A 1 480 ? 57.516 135.760 62.547 1.00 18.18 ? 480 TRP M N 1 ATOM 3894 C CA . TRP A 1 480 ? 58.668 134.841 62.472 1.00 18.46 ? 480 TRP M CA 1 ATOM 3895 C C . TRP A 1 480 ? 59.883 135.322 63.231 1.00 20.72 ? 480 TRP M C 1 ATOM 3896 O O . TRP A 1 480 ? 60.810 134.558 63.484 1.00 19.12 ? 480 TRP M O 1 ATOM 3897 C CB . TRP A 1 480 ? 59.031 134.362 61.051 1.00 19.18 ? 480 TRP M CB 1 ATOM 3898 C CG . TRP A 1 480 ? 57.827 133.661 60.459 1.00 18.38 ? 480 TRP M CG 1 ATOM 3899 C CD1 . TRP A 1 480 ? 57.126 134.055 59.359 1.00 19.46 ? 480 TRP M CD1 1 ATOM 3900 C CD2 . TRP A 1 480 ? 57.151 132.521 60.992 1.00 13.38 ? 480 TRP M CD2 1 ATOM 3901 N NE1 . TRP A 1 480 ? 56.067 133.230 59.172 1.00 18.18 ? 480 TRP M NE1 1 ATOM 3902 C CE2 . TRP A 1 480 ? 55.996 132.321 60.170 1.00 16.15 ? 480 TRP M CE2 1 ATOM 3903 C CE3 . TRP A 1 480 ? 57.365 131.649 62.079 1.00 17.48 ? 480 TRP M CE3 1 ATOM 3904 C CZ2 . TRP A 1 480 ? 55.146 131.238 60.383 1.00 17.23 ? 480 TRP M CZ2 1 ATOM 3905 C CZ3 . TRP A 1 480 ? 56.467 130.608 62.297 1.00 18.35 ? 480 TRP M CZ3 1 ATOM 3906 C CH2 . TRP A 1 480 ? 55.380 130.435 61.428 1.00 16.63 ? 480 TRP M CH2 1 ATOM 3907 N N . ASN A 1 481 ? 59.864 136.575 63.597 1.00 22.18 ? 481 ASN M N 1 ATOM 3908 C CA . ASN A 1 481 ? 60.971 137.100 64.454 1.00 23.92 ? 481 ASN M CA 1 ATOM 3909 C C . ASN A 1 481 ? 60.737 136.870 65.915 1.00 24.12 ? 481 ASN M C 1 ATOM 3910 O O . ASN A 1 481 ? 61.637 137.071 66.774 1.00 24.87 ? 481 ASN M O 1 ATOM 3911 C CB . ASN A 1 481 ? 61.168 138.603 64.187 1.00 26.11 ? 481 ASN M CB 1 ATOM 3912 C CG . ASN A 1 481 ? 61.653 138.864 62.758 1.00 28.57 ? 481 ASN M CG 1 ATOM 3913 O OD1 . ASN A 1 481 ? 62.561 138.189 62.276 1.00 37.79 ? 481 ASN M OD1 1 ATOM 3914 N ND2 . ASN A 1 481 ? 61.035 139.817 62.069 1.00 42.73 ? 481 ASN M ND2 1 ATOM 3915 N N . ASN A 1 482 ? 59.492 136.522 66.266 1.00 20.03 ? 482 ASN M N 1 ATOM 3916 C CA . ASN A 1 482 ? 59.147 136.271 67.637 1.00 20.09 ? 482 ASN M CA 1 ATOM 3917 C C . ASN A 1 482 ? 57.853 135.501 67.726 1.00 19.17 ? 482 ASN M C 1 ATOM 3918 O O . ASN A 1 482 ? 56.731 136.058 67.810 1.00 19.02 ? 482 ASN M O 1 ATOM 3919 C CB . ASN A 1 482 ? 58.997 137.547 68.461 1.00 23.58 ? 482 ASN M CB 1 ATOM 3920 C CG . ASN A 1 482 ? 58.777 137.228 69.912 1.00 25.81 ? 482 ASN M CG 1 ATOM 3921 O OD1 . ASN A 1 482 ? 58.572 136.046 70.396 1.00 27.89 ? 482 ASN M OD1 1 ATOM 3922 N ND2 . ASN A 1 482 ? 58.767 138.298 70.669 1.00 30.74 ? 482 ASN M ND2 1 ATOM 3923 N N . VAL A 1 483 ? 58.031 134.159 67.699 1.00 18.37 ? 483 VAL M N 1 ATOM 3924 C CA . VAL A 1 483 ? 56.860 133.275 67.435 1.00 17.24 ? 483 VAL M CA 1 ATOM 3925 C C . VAL A 1 483 ? 55.934 133.063 68.590 1.00 19.58 ? 483 VAL M C 1 ATOM 3926 O O . VAL A 1 483 ? 55.025 132.246 68.501 1.00 18.92 ? 483 VAL M O 1 ATOM 3927 C CB . VAL A 1 483 ? 57.355 131.910 66.859 1.00 16.93 ? 483 VAL M CB 1 ATOM 3928 C CG1 . VAL A 1 483 ? 58.252 132.159 65.654 1.00 13.31 ? 483 VAL M CG1 1 ATOM 3929 C CG2 . VAL A 1 483 ? 58.151 131.076 67.980 1.00 18.76 ? 483 VAL M CG2 1 ATOM 3930 N N . THR A 1 484 ? 56.189 133.630 69.757 1.00 18.88 ? 484 THR M N 1 ATOM 3931 C CA . THR A 1 484 ? 55.356 133.328 70.907 1.00 19.94 ? 484 THR M CA 1 ATOM 3932 C C . THR A 1 484 ? 53.859 133.570 70.682 1.00 18.65 ? 484 THR M C 1 ATOM 3933 O O . THR A 1 484 ? 53.025 132.660 70.928 1.00 21.95 ? 484 THR M O 1 ATOM 3934 C CB . THR A 1 484 ? 55.796 134.191 72.091 1.00 21.63 ? 484 THR M CB 1 ATOM 3935 O OG1 . THR A 1 484 ? 57.163 133.815 72.432 1.00 22.13 ? 484 THR M OG1 1 ATOM 3936 C CG2 . THR A 1 484 ? 54.920 133.953 73.295 1.00 21.73 ? 484 THR M CG2 1 ATOM 3937 N N . ASP A 1 485 ? 53.482 134.782 70.304 1.00 20.18 ? 485 ASP M N 1 ATOM 3938 C CA . ASP A 1 485 ? 52.076 135.066 70.192 1.00 19.87 ? 485 ASP M CA 1 ATOM 3939 C C . ASP A 1 485 ? 51.459 134.416 68.926 1.00 19.25 ? 485 ASP M C 1 ATOM 3940 O O . ASP A 1 485 ? 52.117 134.338 67.832 1.00 19.52 ? 485 ASP M O 1 ATOM 3941 C CB . ASP A 1 485 ? 51.831 136.577 70.089 1.00 21.84 ? 485 ASP M CB 1 ATOM 3942 C CG . ASP A 1 485 ? 52.052 137.315 71.365 1.00 30.47 ? 485 ASP M CG 1 ATOM 3943 O OD1 . ASP A 1 485 ? 52.033 136.719 72.450 1.00 29.63 ? 485 ASP M OD1 1 ATOM 3944 O OD2 . ASP A 1 485 ? 52.213 138.565 71.242 1.00 30.42 ? 485 ASP M OD2 1 ATOM 3945 N N . ARG A 1 486 ? 50.137 134.114 69.043 1.00 18.74 ? 486 ARG M N 1 ATOM 3946 C CA . ARG A 1 486 ? 49.290 133.765 67.885 1.00 19.79 ? 486 ARG M CA 1 ATOM 3947 C C . ARG A 1 486 ? 48.130 134.769 67.966 1.00 19.69 ? 486 ARG M C 1 ATOM 3948 O O . ARG A 1 486 ? 47.312 134.674 68.880 1.00 22.95 ? 486 ARG M O 1 ATOM 3949 C CB . ARG A 1 486 ? 48.708 132.335 68.049 1.00 20.65 ? 486 ARG M CB 1 ATOM 3950 C CG . ARG A 1 486 ? 49.724 131.242 67.902 1.00 20.35 ? 486 ARG M CG 1 ATOM 3951 C CD . ARG A 1 486 ? 50.356 130.825 69.280 1.00 19.64 ? 486 ARG M CD 1 ATOM 3952 N NE . ARG A 1 486 ? 51.054 129.505 69.130 1.00 17.86 ? 486 ARG M NE 1 ATOM 3953 C CZ . ARG A 1 486 ? 52.339 129.326 68.835 1.00 14.62 ? 486 ARG M CZ 1 ATOM 3954 N NH1 . ARG A 1 486 ? 53.205 130.304 68.873 1.00 17.45 ? 486 ARG M NH1 1 ATOM 3955 N NH2 . ARG A 1 486 ? 52.803 128.103 68.628 1.00 17.73 ? 486 ARG M NH2 1 ATOM 3956 N N . ASP A 1 487 ? 48.100 135.737 67.073 1.00 19.38 ? 487 ASP M N 1 ATOM 3957 C CA . ASP A 1 487 ? 47.079 136.826 67.165 1.00 19.61 ? 487 ASP M CA 1 ATOM 3958 C C . ASP A 1 487 ? 45.987 136.598 66.145 1.00 16.51 ? 487 ASP M C 1 ATOM 3959 O O . ASP A 1 487 ? 46.328 136.465 64.951 1.00 15.28 ? 487 ASP M O 1 ATOM 3960 C CB . ASP A 1 487 ? 47.773 138.145 66.830 1.00 22.21 ? 487 ASP M CB 1 ATOM 3961 C CG . ASP A 1 487 ? 48.889 138.514 67.879 1.00 30.27 ? 487 ASP M CG 1 ATOM 3962 O OD1 . ASP A 1 487 ? 48.770 138.077 69.034 1.00 29.50 ? 487 ASP M OD1 1 ATOM 3963 O OD2 . ASP A 1 487 ? 49.804 139.279 67.501 1.00 32.88 ? 487 ASP M OD2 1 ATOM 3964 N N . LEU A 1 488 ? 44.723 136.533 66.568 1.00 16.34 ? 488 LEU M N 1 ATOM 3965 C CA . LEU A 1 488 ? 43.625 136.220 65.618 1.00 13.37 ? 488 LEU M CA 1 ATOM 3966 C C . LEU A 1 488 ? 43.653 137.309 64.542 1.00 14.36 ? 488 LEU M C 1 ATOM 3967 O O . LEU A 1 488 ? 43.668 138.538 64.780 1.00 16.44 ? 488 LEU M O 1 ATOM 3968 C CB . LEU A 1 488 ? 42.223 136.215 66.241 1.00 15.54 ? 488 LEU M CB 1 ATOM 3969 C CG . LEU A 1 488 ? 41.838 135.203 67.239 1.00 19.15 ? 488 LEU M CG 1 ATOM 3970 C CD1 . LEU A 1 488 ? 40.353 135.295 67.577 1.00 21.03 ? 488 LEU M CD1 1 ATOM 3971 C CD2 . LEU A 1 488 ? 42.142 133.842 66.717 1.00 21.07 ? 488 LEU M CD2 1 ATOM 3972 N N . LYS A 1 489 ? 43.620 136.858 63.287 1.00 11.69 ? 489 LYS M N 1 ATOM 3973 C CA . LYS A 1 489 ? 43.471 137.670 62.119 1.00 10.04 ? 489 LYS M CA 1 ATOM 3974 C C . LYS A 1 489 ? 41.969 138.119 61.993 1.00 10.82 ? 489 LYS M C 1 ATOM 3975 O O . LYS A 1 489 ? 41.124 137.642 62.723 1.00 11.60 ? 489 LYS M O 1 ATOM 3976 C CB . LYS A 1 489 ? 43.970 136.946 60.861 1.00 12.67 ? 489 LYS M CB 1 ATOM 3977 C CG . LYS A 1 489 ? 45.395 136.507 60.888 1.00 9.80 ? 489 LYS M CG 1 ATOM 3978 C CD . LYS A 1 489 ? 45.702 135.708 59.704 1.00 11.82 ? 489 LYS M CD 1 ATOM 3979 C CE . LYS A 1 489 ? 47.129 135.158 59.695 1.00 10.85 ? 489 LYS M CE 1 ATOM 3980 N NZ . LYS A 1 489 ? 47.410 134.306 58.538 1.00 8.76 ? 489 LYS M NZ 1 ATOM 3981 N N . LYS A 1 490 ? 41.606 138.886 60.985 1.00 11.75 ? 490 LYS M N 1 ATOM 3982 C CA . LYS A 1 490 ? 40.221 139.116 60.656 1.00 11.89 ? 490 LYS M CA 1 ATOM 3983 C C . LYS A 1 490 ? 39.403 137.826 60.459 1.00 11.26 ? 490 LYS M C 1 ATOM 3984 O O . LYS A 1 490 ? 38.269 137.704 60.915 1.00 12.63 ? 490 LYS M O 1 ATOM 3985 C CB . LYS A 1 490 ? 40.032 140.003 59.453 1.00 12.76 ? 490 LYS M CB 1 ATOM 3986 C CG . LYS A 1 490 ? 40.452 141.506 59.607 1.00 17.02 ? 490 LYS M CG 1 ATOM 3987 C CD . LYS A 1 490 ? 39.412 142.153 60.539 1.00 21.27 ? 490 LYS M CD 1 ATOM 3988 C CE . LYS A 1 490 ? 39.732 143.674 60.606 1.00 26.47 ? 490 LYS M CE 1 ATOM 3989 N NZ . LYS A 1 490 ? 38.655 144.461 61.349 1.00 28.90 ? 490 LYS M NZ 1 ATOM 3990 N N . SER A 1 491 ? 40.081 136.867 59.810 1.00 11.66 ? 491 SER M N 1 ATOM 3991 C CA . SER A 1 491 ? 39.438 135.557 59.627 1.00 10.21 ? 491 SER M CA 1 ATOM 3992 C C . SER A 1 491 ? 39.187 134.891 60.972 1.00 11.26 ? 491 SER M C 1 ATOM 3993 O O . SER A 1 491 ? 38.092 134.324 61.139 1.00 11.34 ? 491 SER M O 1 ATOM 3994 C CB . SER A 1 491 ? 40.238 134.690 58.695 1.00 10.86 ? 491 SER M CB 1 ATOM 3995 O OG . SER A 1 491 ? 41.502 134.443 59.229 1.00 12.89 ? 491 SER M OG 1 ATOM 3996 N N . GLY A 1 492 ? 40.174 134.867 61.872 1.00 10.96 ? 492 GLY M N 1 ATOM 3997 C CA . GLY A 1 492 ? 39.954 134.298 63.205 1.00 10.97 ? 492 GLY M CA 1 ATOM 3998 C C . GLY A 1 492 ? 38.835 134.963 63.983 1.00 12.28 ? 492 GLY M C 1 ATOM 3999 O O . GLY A 1 492 ? 38.030 134.310 64.633 1.00 11.65 ? 492 GLY M O 1 ATOM 4000 N N . GLN A 1 493 ? 38.802 136.296 63.893 1.00 11.63 ? 493 GLN M N 1 ATOM 4001 C CA . GLN A 1 493 ? 37.737 137.026 64.508 1.00 12.55 ? 493 GLN M CA 1 ATOM 4002 C C . GLN A 1 493 ? 36.369 136.723 63.950 1.00 11.28 ? 493 GLN M C 1 ATOM 4003 O O . GLN A 1 493 ? 35.387 136.561 64.670 1.00 13.43 ? 493 GLN M O 1 ATOM 4004 C CB . GLN A 1 493 ? 38.119 138.537 64.518 1.00 13.88 ? 493 GLN M CB 1 ATOM 4005 C CG . GLN A 1 493 ? 39.343 138.950 65.294 1.00 16.53 ? 493 GLN M CG 1 ATOM 4006 C CD . GLN A 1 493 ? 39.932 140.328 64.813 1.00 26.41 ? 493 GLN M CD 1 ATOM 4007 O OE1 . GLN A 1 493 ? 39.232 141.154 64.559 1.00 26.24 ? 493 GLN M OE1 1 ATOM 4008 N NE2 . GLN A 1 493 ? 41.228 140.407 64.524 1.00 35.11 ? 493 GLN M NE2 1 ATOM 4009 N N . TRP A 1 494 ? 36.310 136.612 62.640 1.00 11.49 ? 494 TRP M N 1 ATOM 4010 C CA . TRP A 1 494 ? 35.124 136.200 61.973 1.00 11.21 ? 494 TRP M CA 1 ATOM 4011 C C . TRP A 1 494 ? 34.619 134.777 62.417 1.00 10.94 ? 494 TRP M C 1 ATOM 4012 O O . TRP A 1 494 ? 33.462 134.524 62.730 1.00 11.81 ? 494 TRP M O 1 ATOM 4013 C CB . TRP A 1 494 ? 35.175 136.309 60.457 1.00 10.28 ? 494 TRP M CB 1 ATOM 4014 C CG . TRP A 1 494 ? 34.122 135.488 59.802 1.00 9.36 ? 494 TRP M CG 1 ATOM 4015 C CD1 . TRP A 1 494 ? 32.777 135.796 59.663 1.00 13.22 ? 494 TRP M CD1 1 ATOM 4016 C CD2 . TRP A 1 494 ? 34.243 134.136 59.271 1.00 12.42 ? 494 TRP M CD2 1 ATOM 4017 N NE1 . TRP A 1 494 ? 32.105 134.765 59.097 1.00 15.12 ? 494 TRP M NE1 1 ATOM 4018 C CE2 . TRP A 1 494 ? 32.957 133.722 58.919 1.00 14.03 ? 494 TRP M CE2 1 ATOM 4019 C CE3 . TRP A 1 494 ? 35.309 133.193 59.238 1.00 11.79 ? 494 TRP M CE3 1 ATOM 4020 C CZ2 . TRP A 1 494 ? 32.694 132.437 58.385 1.00 15.78 ? 494 TRP M CZ2 1 ATOM 4021 C CZ3 . TRP A 1 494 ? 35.052 131.976 58.725 1.00 16.69 ? 494 TRP M CZ3 1 ATOM 4022 C CH2 . TRP A 1 494 ? 33.761 131.601 58.341 1.00 17.61 ? 494 TRP M CH2 1 ATOM 4023 N N . TYR A 1 495 ? 35.586 133.869 62.415 1.00 10.41 ? 495 TYR M N 1 ATOM 4024 C CA . TYR A 1 495 ? 35.249 132.492 62.757 1.00 9.05 ? 495 TYR M CA 1 ATOM 4025 C C . TYR A 1 495 ? 34.757 132.401 64.210 1.00 10.11 ? 495 TYR M C 1 ATOM 4026 O O . TYR A 1 495 ? 33.866 131.615 64.517 1.00 11.97 ? 495 TYR M O 1 ATOM 4027 C CB . TYR A 1 495 ? 36.464 131.605 62.518 1.00 9.56 ? 495 TYR M CB 1 ATOM 4028 C CG . TYR A 1 495 ? 36.223 130.105 62.473 1.00 10.14 ? 495 TYR M CG 1 ATOM 4029 C CD1 . TYR A 1 495 ? 35.156 129.553 61.827 1.00 10.52 ? 495 TYR M CD1 1 ATOM 4030 C CD2 . TYR A 1 495 ? 37.160 129.265 63.047 1.00 10.81 ? 495 TYR M CD2 1 ATOM 4031 C CE1 . TYR A 1 495 ? 34.988 128.215 61.679 1.00 10.64 ? 495 TYR M CE1 1 ATOM 4032 C CE2 . TYR A 1 495 ? 37.011 127.906 62.878 1.00 10.77 ? 495 TYR M CE2 1 ATOM 4033 C CZ . TYR A 1 495 ? 35.947 127.369 62.233 1.00 9.17 ? 495 TYR M CZ 1 ATOM 4034 O OH . TYR A 1 495 ? 35.793 125.972 62.073 1.00 10.00 ? 495 TYR M OH 1 ATOM 4035 N N . GLN A 1 496 ? 35.340 133.206 65.084 1.00 11.40 ? 496 GLN M N 1 ATOM 4036 C CA . GLN A 1 496 ? 34.877 133.330 66.489 1.00 13.11 ? 496 GLN M CA 1 ATOM 4037 C C . GLN A 1 496 ? 33.424 133.710 66.467 1.00 15.02 ? 496 GLN M C 1 ATOM 4038 O O . GLN A 1 496 ? 32.605 133.095 67.183 1.00 13.15 ? 496 GLN M O 1 ATOM 4039 C CB . GLN A 1 496 ? 35.723 134.353 67.264 1.00 14.85 ? 496 GLN M CB 1 ATOM 4040 C CG . GLN A 1 496 ? 35.378 134.565 68.699 1.00 15.94 ? 496 GLN M CG 1 ATOM 4041 C CD . GLN A 1 496 ? 36.314 135.662 69.294 1.00 24.27 ? 496 GLN M CD 1 ATOM 4042 O OE1 . GLN A 1 496 ? 36.498 136.754 68.661 1.00 27.79 ? 496 GLN M OE1 1 ATOM 4043 N NE2 . GLN A 1 496 ? 36.929 135.421 70.424 1.00 25.46 ? 496 GLN M NE2 1 ATOM 4044 N N . SER A 1 497 ? 33.025 134.685 65.663 1.00 12.33 ? 497 SER M N 1 ATOM 4045 C CA . SER A 1 497 ? 31.639 135.083 65.662 1.00 14.46 ? 497 SER M CA 1 ATOM 4046 C C . SER A 1 497 ? 30.730 134.115 64.975 1.00 13.71 ? 497 SER M C 1 ATOM 4047 O O . SER A 1 497 ? 29.592 133.862 65.367 1.00 16.16 ? 497 SER M O 1 ATOM 4048 C CB . SER A 1 497 ? 31.558 136.469 64.974 1.00 15.02 ? 497 SER M CB 1 ATOM 4049 O OG . SER A 1 497 ? 30.274 137.133 65.176 1.00 31.45 ? 497 SER M OG 1 ATOM 4050 N N . PHE A 1 498 ? 31.219 133.430 63.905 1.00 12.73 ? 498 PHE M N 1 ATOM 4051 C CA . PHE A 1 498 ? 30.459 132.365 63.265 1.00 11.53 ? 498 PHE M CA 1 ATOM 4052 C C . PHE A 1 498 ? 30.140 131.248 64.281 1.00 12.30 ? 498 PHE M C 1 ATOM 4053 O O . PHE A 1 498 ? 29.038 130.727 64.311 1.00 13.08 ? 498 PHE M O 1 ATOM 4054 C CB . PHE A 1 498 ? 31.309 131.810 62.105 1.00 10.48 ? 498 PHE M CB 1 ATOM 4055 C CG . PHE A 1 498 ? 30.814 130.554 61.506 1.00 9.91 ? 498 PHE M CG 1 ATOM 4056 C CD1 . PHE A 1 498 ? 31.151 129.320 62.087 1.00 12.32 ? 498 PHE M CD1 1 ATOM 4057 C CD2 . PHE A 1 498 ? 30.004 130.555 60.416 1.00 13.37 ? 498 PHE M CD2 1 ATOM 4058 C CE1 . PHE A 1 498 ? 30.617 128.149 61.556 1.00 12.72 ? 498 PHE M CE1 1 ATOM 4059 C CE2 . PHE A 1 498 ? 29.424 129.353 59.935 1.00 14.67 ? 498 PHE M CE2 1 ATOM 4060 C CZ . PHE A 1 498 ? 29.776 128.207 60.503 1.00 13.17 ? 498 PHE M CZ 1 ATOM 4061 N N . ILE A 1 499 ? 31.164 130.926 65.063 1.00 11.39 ? 499 ILE M N 1 ATOM 4062 C CA . ILE A 1 499 ? 31.006 129.843 66.049 1.00 12.77 ? 499 ILE M CA 1 ATOM 4063 C C . ILE A 1 499 ? 30.010 130.261 67.190 1.00 15.38 ? 499 ILE M C 1 ATOM 4064 O O . ILE A 1 499 ? 29.210 129.429 67.585 1.00 15.23 ? 499 ILE M O 1 ATOM 4065 C CB . ILE A 1 499 ? 32.331 129.354 66.648 1.00 12.91 ? 499 ILE M CB 1 ATOM 4066 C CG1 . ILE A 1 499 ? 33.113 128.662 65.524 1.00 12.41 ? 499 ILE M CG1 1 ATOM 4067 C CG2 . ILE A 1 499 ? 32.143 128.386 67.853 1.00 12.03 ? 499 ILE M CG2 1 ATOM 4068 C CD1 . ILE A 1 499 ? 34.573 128.256 65.900 1.00 11.78 ? 499 ILE M CD1 1 ATOM 4069 N N . SER A 1 500 ? 30.140 131.505 67.667 1.00 16.10 ? 500 SER M N 1 ATOM 4070 C CA . SER A 1 500 ? 29.304 131.952 68.832 1.00 15.85 ? 500 SER M CA 1 ATOM 4071 C C . SER A 1 500 ? 28.578 133.284 68.390 1.00 17.16 ? 500 SER M C 1 ATOM 4072 O O . SER A 1 500 ? 29.080 134.347 68.687 1.00 16.93 ? 500 SER M O 1 ATOM 4073 C CB . SER A 1 500 ? 30.220 132.163 69.958 1.00 16.85 ? 500 SER M CB 1 ATOM 4074 O OG . SER A 1 500 ? 30.857 130.976 70.326 1.00 17.66 ? 500 SER M OG 1 ATOM 4075 N N . PRO A 1 501 ? 27.555 133.172 67.572 1.00 17.11 ? 501 PRO M N 1 ATOM 4076 C CA . PRO A 1 501 ? 27.012 134.387 66.888 1.00 19.86 ? 501 PRO M CA 1 ATOM 4077 C C . PRO A 1 501 ? 26.181 135.244 67.903 1.00 22.63 ? 501 PRO M C 1 ATOM 4078 O O . PRO A 1 501 ? 26.000 136.442 67.553 1.00 26.59 ? 501 PRO M O 1 ATOM 4079 C CB . PRO A 1 501 ? 26.154 133.806 65.797 1.00 19.81 ? 501 PRO M CB 1 ATOM 4080 C CG . PRO A 1 501 ? 25.737 132.437 66.323 1.00 18.13 ? 501 PRO M CG 1 ATOM 4081 C CD . PRO A 1 501 ? 26.964 131.943 67.044 1.00 16.86 ? 501 PRO M CD 1 ATOM 4082 O OXT . PRO A 1 501 ? 25.872 134.743 68.968 1.00 26.58 ? 501 PRO M OXT 1 HETATM 4083 C C1 . NAG B 2 . ? 22.364 132.425 62.510 1.00 25.15 ? 901 NAG M C1 1 HETATM 4084 C C2 . NAG B 2 . ? 21.770 133.703 63.105 1.00 28.81 ? 901 NAG M C2 1 HETATM 4085 C C3 . NAG B 2 . ? 20.241 133.450 62.931 1.00 36.47 ? 901 NAG M C3 1 HETATM 4086 C C4 . NAG B 2 . ? 19.842 133.187 61.475 1.00 37.94 ? 901 NAG M C4 1 HETATM 4087 C C5 . NAG B 2 . ? 20.703 132.001 60.974 1.00 39.56 ? 901 NAG M C5 1 HETATM 4088 C C6 . NAG B 2 . ? 20.529 131.654 59.523 1.00 36.97 ? 901 NAG M C6 1 HETATM 4089 C C7 . NAG B 2 . ? 22.470 134.995 65.065 1.00 28.34 ? 901 NAG M C7 1 HETATM 4090 C C8 . NAG B 2 . ? 22.754 135.188 66.517 1.00 29.05 ? 901 NAG M C8 1 HETATM 4091 N N2 . NAG B 2 . ? 22.050 133.883 64.507 1.00 24.97 ? 901 NAG M N2 1 HETATM 4092 O O3 . NAG B 2 . ? 19.539 134.502 63.574 1.00 36.73 ? 901 NAG M O3 1 HETATM 4093 O O4 . NAG B 2 . ? 18.445 132.896 61.229 1.00 46.35 ? 901 NAG M O4 1 HETATM 4094 O O5 . NAG B 2 . ? 22.084 132.296 61.162 1.00 28.05 ? 901 NAG M O5 1 HETATM 4095 O O6 . NAG B 2 . ? 21.084 130.361 59.278 1.00 41.70 ? 901 NAG M O6 1 HETATM 4096 O O7 . NAG B 2 . ? 22.665 135.948 64.339 1.00 36.90 ? 901 NAG M O7 1 HETATM 4097 C C1 . NAG C 2 . ? 30.506 129.009 73.627 1.00 19.61 ? 911 NAG M C1 1 HETATM 4098 C C2 . NAG C 2 . ? 29.894 130.310 74.031 1.00 27.20 ? 911 NAG M C2 1 HETATM 4099 C C3 . NAG C 2 . ? 28.653 129.935 74.879 1.00 27.78 ? 911 NAG M C3 1 HETATM 4100 C C4 . NAG C 2 . ? 27.781 129.067 74.022 1.00 27.06 ? 911 NAG M C4 1 HETATM 4101 C C5 . NAG C 2 . ? 28.497 127.814 73.565 1.00 23.37 ? 911 NAG M C5 1 HETATM 4102 C C6 . NAG C 2 . ? 27.591 126.947 72.743 1.00 25.42 ? 911 NAG M C6 1 HETATM 4103 C C7 . NAG C 2 . ? 31.494 132.111 74.424 1.00 31.05 ? 911 NAG M C7 1 HETATM 4104 C C8 . NAG C 2 . ? 32.437 132.769 75.413 1.00 33.70 ? 911 NAG M C8 1 HETATM 4105 N N2 . NAG C 2 . ? 30.847 131.023 74.815 1.00 25.94 ? 911 NAG M N2 1 HETATM 4106 O O3 . NAG C 2 . ? 28.006 131.170 75.201 1.00 31.07 ? 911 NAG M O3 1 HETATM 4107 O O4 . NAG C 2 . ? 26.671 128.618 74.832 1.00 29.89 ? 911 NAG M O4 1 HETATM 4108 O O5 . NAG C 2 . ? 29.687 128.255 72.821 1.00 21.74 ? 911 NAG M O5 1 HETATM 4109 O O6 . NAG C 2 . ? 27.094 127.396 71.503 1.00 28.38 ? 911 NAG M O6 1 HETATM 4110 O O7 . NAG C 2 . ? 31.256 132.574 73.298 1.00 30.18 ? 911 NAG M O7 1 HETATM 4111 C C1 . NAG D 2 . ? 25.210 128.821 73.973 1.00 40.06 ? 913 NAG M C1 1 HETATM 4112 C C2 . NAG D 2 . ? 24.224 128.187 74.969 1.00 40.43 ? 913 NAG M C2 1 HETATM 4113 C C3 . NAG D 2 . ? 22.799 128.498 74.417 1.00 43.27 ? 913 NAG M C3 1 HETATM 4114 C C4 . NAG D 2 . ? 22.580 129.959 74.032 1.00 46.16 ? 913 NAG M C4 1 HETATM 4115 C C5 . NAG D 2 . ? 23.803 130.537 73.252 1.00 46.05 ? 913 NAG M C5 1 HETATM 4116 C C6 . NAG D 2 . ? 23.684 132.038 73.014 1.00 41.84 ? 913 NAG M C6 1 HETATM 4117 C C7 . NAG D 2 . ? 24.913 125.983 75.946 1.00 42.77 ? 913 NAG M C7 1 HETATM 4118 C C8 . NAG D 2 . ? 24.884 124.481 75.697 1.00 41.36 ? 913 NAG M C8 1 HETATM 4119 N N2 . NAG D 2 . ? 24.393 126.754 74.972 1.00 37.87 ? 913 NAG M N2 1 HETATM 4120 O O3 . NAG D 2 . ? 21.802 128.142 75.375 1.00 43.81 ? 913 NAG M O3 1 HETATM 4121 O O4 . NAG D 2 . ? 21.394 129.952 73.221 1.00 48.63 ? 913 NAG M O4 1 HETATM 4122 O O5 . NAG D 2 . ? 25.045 130.253 73.914 1.00 42.58 ? 913 NAG M O5 1 HETATM 4123 O O6 . NAG D 2 . ? 23.894 132.679 74.235 1.00 47.59 ? 913 NAG M O6 1 HETATM 4124 O O7 . NAG D 2 . ? 25.392 126.445 76.983 1.00 44.35 ? 913 NAG M O7 1 HETATM 4125 C C1 . NAG E 2 . ? 60.374 101.655 36.187 1.00 14.24 ? 921 NAG M C1 1 HETATM 4126 C C2 . NAG E 2 . ? 61.501 101.758 35.184 1.00 16.63 ? 921 NAG M C2 1 HETATM 4127 C C3 . NAG E 2 . ? 60.916 101.024 33.915 1.00 21.55 ? 921 NAG M C3 1 HETATM 4128 C C4 . NAG E 2 . ? 60.559 99.628 34.188 1.00 24.46 ? 921 NAG M C4 1 HETATM 4129 C C5 . NAG E 2 . ? 59.681 99.597 35.436 1.00 26.81 ? 921 NAG M C5 1 HETATM 4130 C C6 . NAG E 2 . ? 59.380 98.172 35.855 1.00 24.53 ? 921 NAG M C6 1 HETATM 4131 C C7 . NAG E 2 . ? 62.846 103.742 35.091 1.00 20.30 ? 921 NAG M C7 1 HETATM 4132 C C8 . NAG E 2 . ? 62.854 105.204 34.652 1.00 25.33 ? 921 NAG M C8 1 HETATM 4133 N N2 . NAG E 2 . ? 61.714 103.087 34.856 1.00 15.63 ? 921 NAG M N2 1 HETATM 4134 O O3 . NAG E 2 . ? 61.904 101.169 32.881 1.00 24.18 ? 921 NAG M O3 1 HETATM 4135 O O4 . NAG E 2 . ? 59.667 99.217 33.079 1.00 28.02 ? 921 NAG M O4 1 HETATM 4136 O O5 . NAG E 2 . ? 60.322 100.321 36.535 1.00 18.19 ? 921 NAG M O5 1 HETATM 4137 O O6 . NAG E 2 . ? 60.557 97.580 36.381 1.00 35.95 ? 921 NAG M O6 1 HETATM 4138 O O7 . NAG E 2 . ? 63.708 103.159 35.775 1.00 25.30 ? 921 NAG M O7 1 HETATM 4139 C C1 . NAG F 2 . ? 60.231 97.828 32.526 1.00 45.27 ? 923 NAG M C1 1 HETATM 4140 C C2 . NAG F 2 . ? 59.038 97.126 31.866 1.00 42.88 ? 923 NAG M C2 1 HETATM 4141 C C3 . NAG F 2 . ? 59.706 96.065 30.990 1.00 50.28 ? 923 NAG M C3 1 HETATM 4142 C C4 . NAG F 2 . ? 60.999 96.502 30.293 1.00 52.09 ? 923 NAG M C4 1 HETATM 4143 C C5 . NAG F 2 . ? 61.937 97.404 31.120 1.00 53.24 ? 923 NAG M C5 1 HETATM 4144 C C6 . NAG F 2 . ? 63.086 97.964 30.296 1.00 53.66 ? 923 NAG M C6 1 HETATM 4145 C C7 . NAG F 2 . ? 56.802 97.179 32.994 1.00 41.20 ? 923 NAG M C7 1 HETATM 4146 C C8 . NAG F 2 . ? 55.783 96.596 33.948 1.00 42.03 ? 923 NAG M C8 1 HETATM 4147 N N2 . NAG F 2 . ? 58.032 96.567 32.797 1.00 38.83 ? 923 NAG M N2 1 HETATM 4148 O O3 . NAG F 2 . ? 58.809 95.753 29.949 1.00 52.59 ? 923 NAG M O3 1 HETATM 4149 O O4 . NAG F 2 . ? 61.599 95.271 29.928 1.00 54.07 ? 923 NAG M O4 1 HETATM 4150 O O5 . NAG F 2 . ? 61.130 98.479 31.620 1.00 45.78 ? 923 NAG M O5 1 HETATM 4151 O O6 . NAG F 2 . ? 62.511 98.892 29.387 1.00 57.04 ? 923 NAG M O6 1 HETATM 4152 O O7 . NAG F 2 . ? 56.446 98.225 32.425 1.00 41.97 ? 923 NAG M O7 1 HETATM 4153 C C1 . NAG G 2 . ? 45.876 92.239 69.813 1.00 53.06 ? 931 NAG M C1 1 HETATM 4154 C C2 . NAG G 2 . ? 46.470 91.911 68.449 1.00 54.30 ? 931 NAG M C2 1 HETATM 4155 C C3 . NAG G 2 . ? 47.034 90.489 68.712 1.00 59.37 ? 931 NAG M C3 1 HETATM 4156 C C4 . NAG G 2 . ? 47.957 90.492 69.967 1.00 60.32 ? 931 NAG M C4 1 HETATM 4157 C C5 . NAG G 2 . ? 47.206 91.040 71.190 1.00 60.58 ? 931 NAG M C5 1 HETATM 4158 C C6 . NAG G 2 . ? 48.054 91.167 72.446 1.00 61.05 ? 931 NAG M C6 1 HETATM 4159 C C7 . NAG G 2 . ? 45.194 92.692 66.385 1.00 45.76 ? 931 NAG M C7 1 HETATM 4160 C C8 . NAG G 2 . ? 46.270 93.593 65.910 1.00 37.92 ? 931 NAG M C8 1 HETATM 4161 N N2 . NAG G 2 . ? 45.338 91.972 67.501 1.00 48.94 ? 931 NAG M N2 1 HETATM 4162 O O3 . NAG G 2 . ? 47.634 89.945 67.538 1.00 62.70 ? 931 NAG M O3 1 HETATM 4163 O O4 . NAG G 2 . ? 48.461 89.203 70.259 1.00 90.14 ? 931 NAG M O4 1 HETATM 4164 O O5 . NAG G 2 . ? 46.842 92.353 70.834 1.00 51.35 ? 931 NAG M O5 1 HETATM 4165 O O6 . NAG G 2 . ? 49.334 91.515 71.978 1.00 64.14 ? 931 NAG M O6 1 HETATM 4166 O O7 . NAG G 2 . ? 44.181 92.677 65.667 1.00 46.64 ? 931 NAG M O7 1 HETATM 4167 C C1 . NAG H 2 . ? 33.773 121.731 22.805 1.00 12.05 ? 941 NAG M C1 1 HETATM 4168 C C2 . NAG H 2 . ? 34.396 122.807 21.865 1.00 13.84 ? 941 NAG M C2 1 HETATM 4169 C C3 . NAG H 2 . ? 33.626 122.750 20.564 1.00 17.86 ? 941 NAG M C3 1 HETATM 4170 C C4 . NAG H 2 . ? 33.722 121.345 19.980 1.00 15.96 ? 941 NAG M C4 1 HETATM 4171 C C5 . NAG H 2 . ? 33.069 120.382 20.983 1.00 15.01 ? 941 NAG M C5 1 HETATM 4172 C C6 . NAG H 2 . ? 33.055 118.919 20.508 1.00 16.14 ? 941 NAG M C6 1 HETATM 4173 C C7 . NAG H 2 . ? 35.252 124.886 22.801 1.00 15.39 ? 941 NAG M C7 1 HETATM 4174 C C8 . NAG H 2 . ? 34.787 126.162 23.405 1.00 17.26 ? 941 NAG M C8 1 HETATM 4175 N N2 . NAG H 2 . ? 34.200 124.104 22.524 1.00 14.85 ? 941 NAG M N2 1 HETATM 4176 O O3 . NAG H 2 . ? 34.303 123.678 19.661 1.00 18.60 ? 941 NAG M O3 1 HETATM 4177 O O4 . NAG H 2 . ? 32.723 121.331 18.834 1.00 18.26 ? 941 NAG M O4 1 HETATM 4178 O O5 . NAG H 2 . ? 33.915 120.455 22.127 1.00 15.62 ? 941 NAG M O5 1 HETATM 4179 O O6 . NAG H 2 . ? 34.363 118.506 20.208 1.00 18.60 ? 941 NAG M O6 1 HETATM 4180 O O7 . NAG H 2 . ? 36.433 124.609 22.529 1.00 17.72 ? 941 NAG M O7 1 HETATM 4181 C C1 . FUC I 3 . ? 33.529 124.958 19.580 1.00 22.97 ? 942 FUC M C1 1 HETATM 4182 C C2 . FUC I 3 . ? 34.461 125.893 18.882 1.00 31.49 ? 942 FUC M C2 1 HETATM 4183 C C3 . FUC I 3 . ? 34.667 125.436 17.441 1.00 35.94 ? 942 FUC M C3 1 HETATM 4184 C C4 . FUC I 3 . ? 33.333 125.334 16.739 1.00 34.92 ? 942 FUC M C4 1 HETATM 4185 C C5 . FUC I 3 . ? 32.387 124.498 17.577 1.00 31.07 ? 942 FUC M C5 1 HETATM 4186 C C6 . FUC I 3 . ? 30.954 124.589 17.068 1.00 29.45 ? 942 FUC M C6 1 HETATM 4187 O O2 . FUC I 3 . ? 35.769 125.808 19.437 1.00 36.02 ? 942 FUC M O2 1 HETATM 4188 O O3 . FUC I 3 . ? 35.455 126.447 16.805 1.00 42.02 ? 942 FUC M O3 1 HETATM 4189 O O4 . FUC I 3 . ? 32.749 126.630 16.703 1.00 34.24 ? 942 FUC M O4 1 HETATM 4190 O O5 . FUC I 3 . ? 32.274 124.951 18.944 1.00 27.57 ? 942 FUC M O5 1 HETATM 4191 C C1 . NAG J 2 . ? 33.386 120.812 17.725 1.00 22.10 ? 943 NAG M C1 1 HETATM 4192 C C2 . NAG J 2 . ? 32.325 120.566 16.622 1.00 22.20 ? 943 NAG M C2 1 HETATM 4193 C C3 . NAG J 2 . ? 32.989 120.029 15.385 1.00 29.99 ? 943 NAG M C3 1 HETATM 4194 C C4 . NAG J 2 . ? 34.142 120.900 14.990 1.00 27.43 ? 943 NAG M C4 1 HETATM 4195 C C5 . NAG J 2 . ? 35.175 120.966 16.156 1.00 27.65 ? 943 NAG M C5 1 HETATM 4196 C C6 . NAG J 2 . ? 36.310 121.915 15.779 1.00 32.54 ? 943 NAG M C6 1 HETATM 4197 C C7 . NAG J 2 . ? 30.099 120.045 17.420 1.00 23.13 ? 943 NAG M C7 1 HETATM 4198 C C8 . NAG J 2 . ? 29.108 119.015 17.860 1.00 24.78 ? 943 NAG M C8 1 HETATM 4199 N N2 . NAG J 2 . ? 31.291 119.642 17.081 1.00 20.56 ? 943 NAG M N2 1 HETATM 4200 O O3 . NAG J 2 . ? 31.985 120.155 14.377 1.00 30.10 ? 943 NAG M O3 1 HETATM 4201 O O4 . NAG J 2 . ? 34.748 120.191 13.951 1.00 32.15 ? 943 NAG M O4 1 HETATM 4202 O O5 . NAG J 2 . ? 34.459 121.560 17.236 1.00 23.90 ? 943 NAG M O5 1 HETATM 4203 O O6 . NAG J 2 . ? 37.201 121.854 16.892 1.00 39.55 ? 943 NAG M O6 1 HETATM 4204 O O7 . NAG J 2 . ? 29.703 121.206 17.410 1.00 28.11 ? 943 NAG M O7 1 HETATM 4205 C C1 . BMA K 4 . ? 35.203 121.190 12.720 1.00 39.42 ? 944 BMA M C1 1 HETATM 4206 C C2 . BMA K 4 . ? 36.323 120.439 12.026 1.00 39.57 ? 944 BMA M C2 1 HETATM 4207 C C3 . BMA K 4 . ? 36.815 121.261 10.830 1.00 42.81 ? 944 BMA M C3 1 HETATM 4208 C C4 . BMA K 4 . ? 35.556 121.469 9.989 1.00 40.60 ? 944 BMA M C4 1 HETATM 4209 C C5 . BMA K 4 . ? 34.435 122.148 10.799 1.00 40.63 ? 944 BMA M C5 1 HETATM 4210 C C6 . BMA K 4 . ? 33.190 122.567 10.056 1.00 37.61 ? 944 BMA M C6 1 HETATM 4211 O O2 . BMA K 4 . ? 35.701 119.172 11.635 1.00 38.42 ? 944 BMA M O2 1 HETATM 4212 O O3 . BMA K 4 . ? 38.018 120.719 10.204 1.00 47.54 ? 944 BMA M O3 1 HETATM 4213 O O4 . BMA K 4 . ? 35.909 122.361 8.949 1.00 46.09 ? 944 BMA M O4 1 HETATM 4214 O O5 . BMA K 4 . ? 34.022 121.285 11.916 1.00 37.91 ? 944 BMA M O5 1 HETATM 4215 O O6 . BMA K 4 . ? 32.644 121.378 9.448 1.00 39.34 ? 944 BMA M O6 1 HETATM 4216 C C1B . XYP L 5 . ? 36.536 117.875 12.339 1.00 40.03 ? 945 XYP M C1B 1 HETATM 4217 C C2B . XYP L 5 . ? 35.610 116.642 12.218 1.00 40.21 ? 945 XYP M C2B 1 HETATM 4218 C C3B . XYP L 5 . ? 36.268 115.427 12.840 1.00 42.51 ? 945 XYP M C3B 1 HETATM 4219 C C4B . XYP L 5 . ? 37.719 115.326 12.279 1.00 41.84 ? 945 XYP M C4B 1 HETATM 4220 C C5B . XYP L 5 . ? 38.530 116.636 12.477 1.00 41.45 ? 945 XYP M C5B 1 HETATM 4221 O O2B . XYP L 5 . ? 34.308 116.893 12.774 1.00 43.05 ? 945 XYP M O2B 1 HETATM 4222 O O3B . XYP L 5 . ? 35.359 114.383 12.408 1.00 42.88 ? 945 XYP M O3B 1 HETATM 4223 O O4B . XYP L 5 . ? 38.507 114.286 12.860 1.00 45.40 ? 945 XYP M O4B 1 HETATM 4224 O O5B . XYP L 5 . ? 37.849 117.684 11.796 1.00 37.65 ? 945 XYP M O5B 1 HETATM 4225 C C1 . NAG M 2 . ? 34.441 94.684 43.809 1.00 16.07 ? 951 NAG M C1 1 HETATM 4226 C C2 . NAG M 2 . ? 34.445 95.234 42.360 1.00 16.22 ? 951 NAG M C2 1 HETATM 4227 C C3 . NAG M 2 . ? 34.153 94.139 41.283 1.00 17.51 ? 951 NAG M C3 1 HETATM 4228 C C4 . NAG M 2 . ? 34.937 92.946 41.623 1.00 19.53 ? 951 NAG M C4 1 HETATM 4229 C C5 . NAG M 2 . ? 34.823 92.561 43.100 1.00 21.89 ? 951 NAG M C5 1 HETATM 4230 C C6 . NAG M 2 . ? 35.746 91.456 43.533 1.00 25.52 ? 951 NAG M C6 1 HETATM 4231 C C7 . NAG M 2 . ? 34.150 97.631 41.820 1.00 23.75 ? 951 NAG M C7 1 HETATM 4232 C C8 . NAG M 2 . ? 33.100 98.724 41.762 1.00 24.03 ? 951 NAG M C8 1 HETATM 4233 N N2 . NAG M 2 . ? 33.660 96.428 42.225 1.00 18.05 ? 951 NAG M N2 1 HETATM 4234 O O3 . NAG M 2 . ? 34.306 94.494 39.924 1.00 18.84 ? 951 NAG M O3 1 HETATM 4235 O O4 . NAG M 2 . ? 34.530 91.801 40.831 1.00 22.55 ? 951 NAG M O4 1 HETATM 4236 O O5 . NAG M 2 . ? 35.317 93.668 43.974 1.00 19.29 ? 951 NAG M O5 1 HETATM 4237 O O6 . NAG M 2 . ? 35.420 91.035 44.868 1.00 27.28 ? 951 NAG M O6 1 HETATM 4238 O O7 . NAG M 2 . ? 35.408 97.801 41.651 1.00 20.79 ? 951 NAG M O7 1 HETATM 4239 C C1 . FUC N 3 . ? 33.055 94.894 39.273 1.00 24.67 ? 952 FUC M C1 1 HETATM 4240 C C2 . FUC N 3 . ? 33.541 95.577 38.044 1.00 25.87 ? 952 FUC M C2 1 HETATM 4241 C C3 . FUC N 3 . ? 34.325 94.665 37.167 1.00 22.67 ? 952 FUC M C3 1 HETATM 4242 C C4 . FUC N 3 . ? 33.470 93.434 36.806 1.00 27.22 ? 952 FUC M C4 1 HETATM 4243 C C5 . FUC N 3 . ? 33.023 92.750 38.058 1.00 30.50 ? 952 FUC M C5 1 HETATM 4244 C C6 . FUC N 3 . ? 32.176 91.562 37.653 1.00 31.95 ? 952 FUC M C6 1 HETATM 4245 O O2 . FUC N 3 . ? 34.142 96.798 38.344 1.00 26.03 ? 952 FUC M O2 1 HETATM 4246 O O3 . FUC N 3 . ? 34.550 95.464 36.062 1.00 25.57 ? 952 FUC M O3 1 HETATM 4247 O O4 . FUC N 3 . ? 32.357 93.834 36.019 1.00 30.09 ? 952 FUC M O4 1 HETATM 4248 O O5 . FUC N 3 . ? 32.388 93.681 38.913 1.00 24.90 ? 952 FUC M O5 1 HETATM 4249 C C1 . NAG O 2 . ? 35.711 91.002 40.268 1.00 23.17 ? 953 NAG M C1 1 HETATM 4250 C C2 . NAG O 2 . ? 35.049 89.647 39.764 1.00 19.82 ? 953 NAG M C2 1 HETATM 4251 C C3 . NAG O 2 . ? 35.995 88.815 38.982 1.00 29.62 ? 953 NAG M C3 1 HETATM 4252 C C4 . NAG O 2 . ? 36.577 89.735 37.889 1.00 21.78 ? 953 NAG M C4 1 HETATM 4253 C C5 . NAG O 2 . ? 37.072 91.149 38.418 1.00 20.25 ? 953 NAG M C5 1 HETATM 4254 C C6 . NAG O 2 . ? 37.615 92.016 37.312 1.00 23.57 ? 953 NAG M C6 1 HETATM 4255 C C7 . NAG O 2 . ? 33.301 88.815 41.340 1.00 22.35 ? 953 NAG M C7 1 HETATM 4256 C C8 . NAG O 2 . ? 33.233 87.993 42.588 1.00 27.43 ? 953 NAG M C8 1 HETATM 4257 N N2 . NAG O 2 . ? 34.609 88.911 40.957 1.00 26.29 ? 953 NAG M N2 1 HETATM 4258 O O3 . NAG O 2 . ? 34.995 87.890 38.456 1.00 30.45 ? 953 NAG M O3 1 HETATM 4259 O O4 . NAG O 2 . ? 37.693 89.143 37.377 1.00 24.83 ? 953 NAG M O4 1 HETATM 4260 O O5 . NAG O 2 . ? 36.020 91.757 39.091 1.00 20.87 ? 953 NAG M O5 1 HETATM 4261 O O6 . NAG O 2 . ? 38.282 93.139 37.979 1.00 23.02 ? 953 NAG M O6 1 HETATM 4262 O O7 . NAG O 2 . ? 32.293 89.297 40.695 1.00 33.61 ? 953 NAG M O7 1 HETATM 4263 C C1 . BMA P 4 . ? 37.570 88.616 35.973 1.00 28.17 ? 954 BMA M C1 1 HETATM 4264 C C2 . BMA P 4 . ? 38.906 88.363 35.302 1.00 26.78 ? 954 BMA M C2 1 HETATM 4265 C C3 . BMA P 4 . ? 38.638 87.491 34.080 1.00 30.23 ? 954 BMA M C3 1 HETATM 4266 C C4 . BMA P 4 . ? 37.929 86.231 34.349 1.00 28.20 ? 954 BMA M C4 1 HETATM 4267 C C5 . BMA P 4 . ? 36.650 86.647 35.109 1.00 24.98 ? 954 BMA M C5 1 HETATM 4268 C C6 . BMA P 4 . ? 35.750 85.531 35.458 1.00 24.81 ? 954 BMA M C6 1 HETATM 4269 O O2 . BMA P 4 . ? 39.599 87.603 36.256 1.00 30.38 ? 954 BMA M O2 1 HETATM 4270 O O3 . BMA P 4 . ? 39.836 86.951 33.545 1.00 33.44 ? 954 BMA M O3 1 HETATM 4271 O O4 . BMA P 4 . ? 37.606 85.592 33.021 1.00 26.86 ? 954 BMA M O4 1 HETATM 4272 O O5 . BMA P 4 . ? 36.929 87.370 36.352 1.00 22.84 ? 954 BMA M O5 1 HETATM 4273 O O6 . BMA P 4 . ? 36.596 84.520 36.041 1.00 24.07 ? 954 BMA M O6 1 HETATM 4274 C C1B . XYP Q 5 . ? 40.890 88.181 36.853 1.00 38.10 ? 955 XYP M C1B 1 HETATM 4275 C C2B . XYP Q 5 . ? 41.460 87.437 38.023 1.00 30.49 ? 955 XYP M C2B 1 HETATM 4276 C C3B . XYP Q 5 . ? 42.603 88.331 38.475 1.00 39.25 ? 955 XYP M C3B 1 HETATM 4277 C C4B . XYP Q 5 . ? 43.516 88.629 37.299 1.00 41.37 ? 955 XYP M C4B 1 HETATM 4278 C C5B . XYP Q 5 . ? 42.790 89.238 36.092 1.00 43.65 ? 955 XYP M C5B 1 HETATM 4279 O O2B . XYP Q 5 . ? 40.467 87.384 39.058 1.00 32.64 ? 955 XYP M O2B 1 HETATM 4280 O O3B . XYP Q 5 . ? 43.298 87.611 39.471 1.00 39.17 ? 955 XYP M O3B 1 HETATM 4281 O O4B . XYP Q 5 . ? 44.537 89.491 37.788 1.00 47.00 ? 955 XYP M O4B 1 HETATM 4282 O O5B . XYP Q 5 . ? 41.777 88.286 35.740 1.00 37.23 ? 955 XYP M O5B 1 HETATM 4283 C C1 . MAN R 6 . ? 40.037 87.238 32.029 1.00 39.30 ? 956 MAN M C1 1 HETATM 4284 C C2 . MAN R 6 . ? 41.121 86.348 31.428 1.00 40.34 ? 956 MAN M C2 1 HETATM 4285 C C3 . MAN R 6 . ? 42.483 86.901 31.884 1.00 45.03 ? 956 MAN M C3 1 HETATM 4286 C C4 . MAN R 6 . ? 42.596 88.453 31.729 1.00 45.54 ? 956 MAN M C4 1 HETATM 4287 C C5 . MAN R 6 . ? 41.407 89.157 32.406 1.00 44.99 ? 956 MAN M C5 1 HETATM 4288 C C6 . MAN R 6 . ? 41.387 90.667 32.253 1.00 48.45 ? 956 MAN M C6 1 HETATM 4289 O O2 . MAN R 6 . ? 40.987 86.301 30.013 1.00 38.39 ? 956 MAN M O2 1 HETATM 4290 O O3 . MAN R 6 . ? 43.427 86.051 31.214 1.00 42.66 ? 956 MAN M O3 1 HETATM 4291 O O4 . MAN R 6 . ? 43.815 88.976 32.293 1.00 43.33 ? 956 MAN M O4 1 HETATM 4292 O O5 . MAN R 6 . ? 40.210 88.644 31.772 1.00 36.33 ? 956 MAN M O5 1 HETATM 4293 O O6 . MAN R 6 . ? 41.311 90.902 30.823 1.00 52.01 ? 956 MAN M O6 1 HETATM 4294 C C1 . MAN S 6 . ? 35.768 83.174 36.550 1.00 42.98 ? 957 MAN M C1 1 HETATM 4295 C C2 . MAN S 6 . ? 36.886 82.195 36.870 1.00 44.53 ? 957 MAN M C2 1 HETATM 4296 C C3 . MAN S 6 . ? 37.544 81.716 35.565 1.00 42.68 ? 957 MAN M C3 1 HETATM 4297 C C4 . MAN S 6 . ? 36.534 81.276 34.458 1.00 44.36 ? 957 MAN M C4 1 HETATM 4298 C C5 . MAN S 6 . ? 35.389 82.330 34.304 1.00 44.39 ? 957 MAN M C5 1 HETATM 4299 C C6 . MAN S 6 . ? 34.270 81.985 33.303 1.00 41.03 ? 957 MAN M C6 1 HETATM 4300 O O2 . MAN S 6 . ? 36.243 81.178 37.588 1.00 43.25 ? 957 MAN M O2 1 HETATM 4301 O O3 . MAN S 6 . ? 38.432 80.645 35.913 1.00 43.43 ? 957 MAN M O3 1 HETATM 4302 O O4 . MAN S 6 . ? 37.229 81.100 33.188 1.00 35.31 ? 957 MAN M O4 1 HETATM 4303 O O5 . MAN S 6 . ? 34.832 82.594 35.628 1.00 44.05 ? 957 MAN M O5 1 HETATM 4304 O O6 . MAN S 6 . ? 33.514 80.862 33.765 1.00 45.04 ? 957 MAN M O6 1 HETATM 4305 C C1 . NAG T 2 . ? 67.894 122.732 43.061 1.00 42.39 ? 961 NAG M C1 1 HETATM 4306 C C2 . NAG T 2 . ? 68.549 123.433 41.867 1.00 46.98 ? 961 NAG M C2 1 HETATM 4307 C C3 . NAG T 2 . ? 69.095 122.330 40.941 1.00 47.08 ? 961 NAG M C3 1 HETATM 4308 C C4 . NAG T 2 . ? 69.763 121.148 41.695 1.00 46.00 ? 961 NAG M C4 1 HETATM 4309 C C5 . NAG T 2 . ? 69.242 120.838 43.081 1.00 39.99 ? 961 NAG M C5 1 HETATM 4310 C C6 . NAG T 2 . ? 70.236 120.029 43.966 1.00 40.15 ? 961 NAG M C6 1 HETATM 4311 C C7 . NAG T 2 . ? 67.538 125.471 40.928 1.00 59.16 ? 961 NAG M C7 1 HETATM 4312 C C8 . NAG T 2 . ? 66.339 126.032 40.206 1.00 61.44 ? 961 NAG M C8 1 HETATM 4313 N N2 . NAG T 2 . ? 67.482 124.164 41.195 1.00 52.80 ? 961 NAG M N2 1 HETATM 4314 O O3 . NAG T 2 . ? 69.984 122.942 39.990 1.00 47.52 ? 961 NAG M O3 1 HETATM 4315 O O4 . NAG T 2 . ? 69.466 119.957 41.012 1.00 53.15 ? 961 NAG M O4 1 HETATM 4316 O O5 . NAG T 2 . ? 68.918 122.058 43.751 1.00 39.40 ? 961 NAG M O5 1 HETATM 4317 O O6 . NAG T 2 . ? 69.437 119.464 45.026 1.00 39.28 ? 961 NAG M O6 1 HETATM 4318 O O7 . NAG T 2 . ? 68.496 126.187 41.245 1.00 63.63 ? 961 NAG M O7 1 HETATM 4319 C C1 . NAG U 2 . ? 70.738 119.820 39.747 1.00 46.22 ? 963 NAG M C1 1 HETATM 4320 C C2 . NAG U 2 . ? 71.416 118.477 39.651 1.00 41.16 ? 963 NAG M C2 1 HETATM 4321 C C3 . NAG U 2 . ? 71.935 118.384 38.203 1.00 48.08 ? 963 NAG M C3 1 HETATM 4322 C C4 . NAG U 2 . ? 70.846 118.727 37.168 1.00 46.92 ? 963 NAG M C4 1 HETATM 4323 C C5 . NAG U 2 . ? 70.171 120.051 37.556 1.00 50.31 ? 963 NAG M C5 1 HETATM 4324 C C6 . NAG U 2 . ? 69.064 120.490 36.616 1.00 48.77 ? 963 NAG M C6 1 HETATM 4325 C C7 . NAG U 2 . ? 72.413 117.659 41.727 1.00 44.82 ? 963 NAG M C7 1 HETATM 4326 C C8 . NAG U 2 . ? 73.589 117.653 42.652 1.00 45.83 ? 963 NAG M C8 1 HETATM 4327 N N2 . NAG U 2 . ? 72.491 118.417 40.638 1.00 40.87 ? 963 NAG M N2 1 HETATM 4328 O O3 . NAG U 2 . ? 72.421 117.069 38.034 1.00 49.61 ? 963 NAG M O3 1 HETATM 4329 O O4 . NAG U 2 . ? 71.294 118.783 35.808 1.00 53.02 ? 963 NAG M O4 1 HETATM 4330 O O5 . NAG U 2 . ? 69.632 119.871 38.862 1.00 43.08 ? 963 NAG M O5 1 HETATM 4331 O O6 . NAG U 2 . ? 68.232 119.393 36.293 1.00 52.74 ? 963 NAG M O6 1 HETATM 4332 O O7 . NAG U 2 . ? 71.414 116.975 41.964 1.00 43.81 ? 963 NAG M O7 1 HETATM 4333 C C1 . NAG V 2 . ? 58.785 113.919 28.902 1.00 58.38 ? 971 NAG M C1 1 HETATM 4334 C C2 . NAG V 2 . ? 58.804 115.432 28.864 1.00 59.51 ? 971 NAG M C2 1 HETATM 4335 C C3 . NAG V 2 . ? 58.253 115.847 27.492 1.00 59.17 ? 971 NAG M C3 1 HETATM 4336 C C4 . NAG V 2 . ? 59.046 115.098 26.418 1.00 60.49 ? 971 NAG M C4 1 HETATM 4337 C C5 . NAG V 2 . ? 59.036 113.558 26.632 1.00 61.95 ? 971 NAG M C5 1 HETATM 4338 C C6 . NAG V 2 . ? 59.839 112.765 25.599 1.00 61.92 ? 971 NAG M C6 1 HETATM 4339 C C7 . NAG V 2 . ? 58.435 116.802 30.857 1.00 60.69 ? 971 NAG M C7 1 HETATM 4340 C C8 . NAG V 2 . ? 57.446 117.282 31.877 1.00 60.28 ? 971 NAG M C8 1 HETATM 4341 N N2 . NAG V 2 . ? 57.975 115.961 29.935 1.00 59.06 ? 971 NAG M N2 1 HETATM 4342 O O3 . NAG V 2 . ? 58.227 117.260 27.317 1.00 57.30 ? 971 NAG M O3 1 HETATM 4343 O O4 . NAG V 2 . ? 58.456 115.465 25.199 1.00 62.78 ? 971 NAG M O4 1 HETATM 4344 O O5 . NAG V 2 . ? 59.593 113.301 27.913 1.00 58.54 ? 971 NAG M O5 1 HETATM 4345 O O6 . NAG V 2 . ? 61.055 113.444 25.401 1.00 62.30 ? 971 NAG M O6 1 HETATM 4346 O O7 . NAG V 2 . ? 59.601 117.189 30.910 1.00 60.80 ? 971 NAG M O7 1 HETATM 4347 C C1 . NAG W 2 . ? 32.977 126.982 30.646 1.00 11.82 ? 981 NAG M C1 1 HETATM 4348 C C2 . NAG W 2 . ? 32.021 126.136 29.768 1.00 11.60 ? 981 NAG M C2 1 HETATM 4349 C C3 . NAG W 2 . ? 30.760 126.978 29.598 1.00 15.41 ? 981 NAG M C3 1 HETATM 4350 C C4 . NAG W 2 . ? 30.137 127.466 30.876 1.00 15.20 ? 981 NAG M C4 1 HETATM 4351 C C5 . NAG W 2 . ? 31.296 128.177 31.660 1.00 15.23 ? 981 NAG M C5 1 HETATM 4352 C C6 . NAG W 2 . ? 30.811 128.565 33.028 1.00 15.46 ? 981 NAG M C6 1 HETATM 4353 C C7 . NAG W 2 . ? 32.772 124.524 28.021 1.00 14.86 ? 981 NAG M C7 1 HETATM 4354 C C8 . NAG W 2 . ? 33.294 124.359 26.646 1.00 14.73 ? 981 NAG M C8 1 HETATM 4355 N N2 . NAG W 2 . ? 32.548 125.792 28.510 1.00 11.64 ? 981 NAG M N2 1 HETATM 4356 O O3 . NAG W 2 . ? 29.724 126.238 28.874 1.00 16.72 ? 981 NAG M O3 1 HETATM 4357 O O4 . NAG W 2 . ? 29.206 128.565 30.560 1.00 18.66 ? 981 NAG M O4 1 HETATM 4358 O O5 . NAG W 2 . ? 32.392 127.277 31.840 1.00 13.53 ? 981 NAG M O5 1 HETATM 4359 O O6 . NAG W 2 . ? 30.460 127.507 33.870 1.00 19.04 ? 981 NAG M O6 1 HETATM 4360 O O7 . NAG W 2 . ? 32.558 123.546 28.760 1.00 13.43 ? 981 NAG M O7 1 HETATM 4361 C C1 . NAG X 2 . ? 27.807 128.293 31.219 1.00 29.25 ? 983 NAG M C1 1 HETATM 4362 C C2 . NAG X 2 . ? 27.106 129.662 31.032 1.00 29.43 ? 983 NAG M C2 1 HETATM 4363 C C3 . NAG X 2 . ? 25.621 129.590 31.242 1.00 38.26 ? 983 NAG M C3 1 HETATM 4364 C C4 . NAG X 2 . ? 25.091 128.566 30.278 1.00 42.51 ? 983 NAG M C4 1 HETATM 4365 C C5 . NAG X 2 . ? 25.874 127.238 30.513 1.00 42.88 ? 983 NAG M C5 1 HETATM 4366 C C6 . NAG X 2 . ? 25.370 126.093 29.609 1.00 45.67 ? 983 NAG M C6 1 HETATM 4367 C C7 . NAG X 2 . ? 28.504 131.514 31.672 1.00 26.61 ? 983 NAG M C7 1 HETATM 4368 C C8 . NAG X 2 . ? 29.061 132.310 32.884 1.00 31.39 ? 983 NAG M C8 1 HETATM 4369 N N2 . NAG X 2 . ? 27.683 130.548 32.008 1.00 22.71 ? 983 NAG M N2 1 HETATM 4370 O O3 . NAG X 2 . ? 25.085 130.866 30.995 1.00 38.07 ? 983 NAG M O3 1 HETATM 4371 O O4 . NAG X 2 . ? 23.717 128.435 30.657 1.00 46.01 ? 983 NAG M O4 1 HETATM 4372 O O5 . NAG X 2 . ? 27.274 127.461 30.185 1.00 37.21 ? 983 NAG M O5 1 HETATM 4373 O O6 . NAG X 2 . ? 25.720 126.506 28.289 1.00 48.20 ? 983 NAG M O6 1 HETATM 4374 O O7 . NAG X 2 . ? 28.916 131.748 30.578 1.00 28.72 ? 983 NAG M O7 1 HETATM 4375 C C1 . NAG Y 2 . ? 58.238 137.958 72.224 1.00 35.99 ? 991 NAG M C1 1 HETATM 4376 C C2 . NAG Y 2 . ? 58.882 139.093 73.074 1.00 40.78 ? 991 NAG M C2 1 HETATM 4377 C C3 . NAG Y 2 . ? 58.235 139.169 74.473 1.00 39.32 ? 991 NAG M C3 1 HETATM 4378 C C4 . NAG Y 2 . ? 56.691 139.240 74.305 1.00 34.49 ? 991 NAG M C4 1 HETATM 4379 C C5 . NAG Y 2 . ? 56.248 138.070 73.360 1.00 33.20 ? 991 NAG M C5 1 HETATM 4380 C C6 . NAG Y 2 . ? 54.741 137.940 73.294 1.00 34.56 ? 991 NAG M C6 1 HETATM 4381 C C7 . NAG Y 2 . ? 61.163 139.895 72.562 1.00 49.00 ? 991 NAG M C7 1 HETATM 4382 C C8 . NAG Y 2 . ? 62.679 139.697 72.577 1.00 46.85 ? 991 NAG M C8 1 HETATM 4383 N N2 . NAG Y 2 . ? 60.343 138.945 73.097 1.00 44.82 ? 991 NAG M N2 1 HETATM 4384 O O3 . NAG Y 2 . ? 58.800 140.304 75.147 1.00 41.68 ? 991 NAG M O3 1 HETATM 4385 O O4 . NAG Y 2 . ? 56.048 139.128 75.571 1.00 39.67 ? 991 NAG M O4 1 HETATM 4386 O O5 . NAG Y 2 . ? 56.842 138.206 72.065 1.00 30.22 ? 991 NAG M O5 1 HETATM 4387 O O6 . NAG Y 2 . ? 54.315 139.115 72.684 1.00 35.79 ? 991 NAG M O6 1 HETATM 4388 O O7 . NAG Y 2 . ? 60.661 140.916 72.081 1.00 53.07 ? 991 NAG M O7 1 HETATM 4389 O O20 . E18 Z 7 . ? 48.425 115.621 46.735 0.80 22.71 ? 1501 E18 M O20 1 HETATM 4390 S S19 . E18 Z 7 . ? 47.904 116.928 46.721 0.80 21.85 ? 1501 E18 M S19 1 HETATM 4391 O O21 . E18 Z 7 . ? 46.511 116.975 46.167 0.80 21.68 ? 1501 E18 M O21 1 HETATM 4392 O O22 . E18 Z 7 . ? 48.718 117.904 45.991 0.80 28.47 ? 1501 E18 M O22 1 HETATM 4393 O O18 . E18 Z 7 . ? 47.743 117.664 48.160 0.80 31.80 ? 1501 E18 M O18 1 HETATM 4394 N N17 . E18 Z 7 . ? 46.893 118.725 48.207 0.80 37.15 ? 1501 E18 M N17 1 HETATM 4395 C C13 . E18 Z 7 . ? 47.064 119.601 49.103 0.80 39.67 ? 1501 E18 M C13 1 HETATM 4396 S S1 . E18 Z 7 . ? 48.391 119.370 50.193 0.80 40.17 ? 1501 E18 M S1 1 HETATM 4397 C C1 . E18 Z 7 . ? 48.293 119.860 51.944 0.80 32.26 ? 1501 E18 M C1 1 HETATM 4398 C C2 . E18 Z 7 . ? 47.781 121.284 52.128 0.80 23.13 ? 1501 E18 M C2 1 HETATM 4399 N N18 . E18 Z 7 . ? 48.401 122.220 53.118 0.80 16.29 ? 1501 E18 M N18 1 HETATM 4400 C C20 . E18 Z 7 . ? 48.314 121.768 54.540 0.80 19.34 ? 1501 E18 M C20 1 HETATM 4401 C C19 . E18 Z 7 . ? 47.623 123.476 53.024 0.80 16.24 ? 1501 E18 M C19 1 HETATM 4402 C CB . E18 Z 7 . ? 46.010 120.723 48.976 0.80 35.86 ? 1501 E18 M CB 1 HETATM 4403 C CG . E18 Z 7 . ? 46.572 121.973 48.390 0.80 24.29 ? 1501 E18 M CG 1 HETATM 4404 C CD2 . E18 Z 7 . ? 46.456 123.207 49.001 0.80 17.89 ? 1501 E18 M CD2 1 HETATM 4405 C CE2 . E18 Z 7 . ? 47.116 124.301 48.557 0.80 23.29 ? 1501 E18 M CE2 1 HETATM 4406 C CZ . E18 Z 7 . ? 47.914 124.181 47.423 0.80 24.67 ? 1501 E18 M CZ 1 HETATM 4407 C CE1 . E18 Z 7 . ? 48.062 122.962 46.828 0.80 23.41 ? 1501 E18 M CE1 1 HETATM 4408 C CD1 . E18 Z 7 . ? 47.434 121.821 47.312 0.80 24.75 ? 1501 E18 M CD1 1 HETATM 4409 ZN ZN . ZN AA 8 . ? 68.147 122.189 60.509 0.50 8.28 ? 1502 ZN M ZN 1 HETATM 4410 S S A SO4 BA 9 . ? 49.756 118.265 43.052 0.50 44.15 ? 1503 SO4 M S 1 HETATM 4411 S S B SO4 BA 9 . ? 48.199 118.646 40.481 0.50 26.44 ? 1503 SO4 M S 1 HETATM 4412 O O1 A SO4 BA 9 . ? 51.110 118.569 42.519 0.50 45.62 ? 1503 SO4 M O1 1 HETATM 4413 O O1 B SO4 BA 9 . ? 49.504 118.609 39.815 0.50 32.94 ? 1503 SO4 M O1 1 HETATM 4414 O O2 A SO4 BA 9 . ? 48.766 117.996 41.968 0.50 29.83 ? 1503 SO4 M O2 1 HETATM 4415 O O2 B SO4 BA 9 . ? 47.239 119.074 39.532 0.50 18.54 ? 1503 SO4 M O2 1 HETATM 4416 O O3 A SO4 BA 9 . ? 50.013 117.052 43.777 0.50 24.02 ? 1503 SO4 M O3 1 HETATM 4417 O O3 B SO4 BA 9 . ? 47.851 117.281 40.942 0.50 29.80 ? 1503 SO4 M O3 1 HETATM 4418 O O4 A SO4 BA 9 . ? 49.279 119.312 43.962 0.50 39.03 ? 1503 SO4 M O4 1 HETATM 4419 O O4 B SO4 BA 9 . ? 48.062 119.801 41.376 0.50 32.87 ? 1503 SO4 M O4 1 HETATM 4420 S S . SO4 CA 9 . ? 66.693 101.683 46.002 0.74 20.68 ? 1504 SO4 M S 1 HETATM 4421 O O1 . SO4 CA 9 . ? 65.838 101.803 44.812 0.74 27.60 ? 1504 SO4 M O1 1 HETATM 4422 O O2 . SO4 CA 9 . ? 66.856 100.341 46.424 0.74 31.47 ? 1504 SO4 M O2 1 HETATM 4423 O O3 . SO4 CA 9 . ? 66.416 102.612 46.993 0.74 22.81 ? 1504 SO4 M O3 1 HETATM 4424 O O4 . SO4 CA 9 . ? 67.974 102.146 45.525 0.74 31.14 ? 1504 SO4 M O4 1 HETATM 4425 S S . SO4 DA 9 . ? 66.265 95.790 65.873 0.80 29.68 ? 1505 SO4 M S 1 HETATM 4426 O O1 . SO4 DA 9 . ? 65.193 94.827 66.150 0.80 32.65 ? 1505 SO4 M O1 1 HETATM 4427 O O2 . SO4 DA 9 . ? 66.229 96.901 66.865 0.80 19.85 ? 1505 SO4 M O2 1 HETATM 4428 O O3 . SO4 DA 9 . ? 66.301 96.115 64.402 0.80 25.42 ? 1505 SO4 M O3 1 HETATM 4429 O O4 . SO4 DA 9 . ? 67.570 95.164 66.213 0.80 31.82 ? 1505 SO4 M O4 1 HETATM 4430 S S . SO4 EA 9 . ? 26.882 133.881 42.388 0.91 19.98 ? 1506 SO4 M S 1 HETATM 4431 O O1 . SO4 EA 9 . ? 26.778 132.451 42.521 0.91 19.91 ? 1506 SO4 M O1 1 HETATM 4432 O O2 . SO4 EA 9 . ? 25.868 134.586 43.111 0.91 23.52 ? 1506 SO4 M O2 1 HETATM 4433 O O3 . SO4 EA 9 . ? 26.867 134.276 41.022 0.91 27.40 ? 1506 SO4 M O3 1 HETATM 4434 O O4 . SO4 EA 9 . ? 28.128 134.430 42.908 0.91 23.64 ? 1506 SO4 M O4 1 HETATM 4435 S S . SO4 FA 9 . ? 38.077 108.718 25.187 0.72 41.24 ? 1507 SO4 M S 1 HETATM 4436 O O1 . SO4 FA 9 . ? 36.775 109.382 25.149 0.72 25.52 ? 1507 SO4 M O1 1 HETATM 4437 O O2 . SO4 FA 9 . ? 39.107 109.818 25.072 0.72 43.03 ? 1507 SO4 M O2 1 HETATM 4438 O O3 . SO4 FA 9 . ? 38.460 107.866 24.015 0.72 40.09 ? 1507 SO4 M O3 1 HETATM 4439 O O4 . SO4 FA 9 . ? 38.246 107.915 26.392 0.72 36.23 ? 1507 SO4 M O4 1 HETATM 4440 S S . SO4 GA 9 . ? 56.127 100.513 75.746 0.68 41.24 ? 1508 SO4 M S 1 HETATM 4441 O O1 . SO4 GA 9 . ? 54.638 100.458 75.953 0.68 29.24 ? 1508 SO4 M O1 1 HETATM 4442 O O2 . SO4 GA 9 . ? 56.578 99.394 76.613 0.68 40.88 ? 1508 SO4 M O2 1 HETATM 4443 O O3 . SO4 GA 9 . ? 56.312 101.832 76.404 0.68 31.94 ? 1508 SO4 M O3 1 HETATM 4444 O O4 . SO4 GA 9 . ? 56.795 100.335 74.398 0.68 18.14 ? 1508 SO4 M O4 1 HETATM 4445 S S . SO4 HA 9 . ? 68.215 127.979 44.985 0.51 42.73 ? 1509 SO4 M S 1 HETATM 4446 O O1 . SO4 HA 9 . ? 66.835 128.154 45.500 0.51 36.00 ? 1509 SO4 M O1 1 HETATM 4447 O O2 . SO4 HA 9 . ? 68.687 129.276 44.489 0.51 42.85 ? 1509 SO4 M O2 1 HETATM 4448 O O3 . SO4 HA 9 . ? 68.274 126.970 43.918 0.51 39.19 ? 1509 SO4 M O3 1 HETATM 4449 O O4 . SO4 HA 9 . ? 69.104 127.575 46.067 0.51 39.31 ? 1509 SO4 M O4 1 HETATM 4450 C C1 . GOL IA 10 . ? 34.841 112.973 17.651 0.56 36.60 ? 2511 GOL M C1 1 HETATM 4451 O O1 . GOL IA 10 . ? 35.949 112.670 18.454 0.56 34.48 ? 2511 GOL M O1 1 HETATM 4452 C C2 . GOL IA 10 . ? 33.675 113.496 18.469 0.56 36.97 ? 2511 GOL M C2 1 HETATM 4453 O O2 . GOL IA 10 . ? 32.920 112.567 19.197 0.56 40.58 ? 2511 GOL M O2 1 HETATM 4454 C C3 . GOL IA 10 . ? 32.716 114.163 17.517 0.56 36.77 ? 2511 GOL M C3 1 HETATM 4455 O O3 . GOL IA 10 . ? 31.405 113.836 17.874 0.56 34.59 ? 2511 GOL M O3 1 HETATM 4456 C C1 . GOL JA 10 . ? 66.873 111.136 51.225 0.90 23.18 ? 2512 GOL M C1 1 HETATM 4457 O O1 . GOL JA 10 . ? 67.903 111.495 52.039 0.90 16.74 ? 2512 GOL M O1 1 HETATM 4458 C C2 . GOL JA 10 . ? 65.557 110.890 52.000 0.90 17.12 ? 2512 GOL M C2 1 HETATM 4459 O O2 . GOL JA 10 . ? 65.806 109.614 52.662 0.90 14.14 ? 2512 GOL M O2 1 HETATM 4460 C C3 . GOL JA 10 . ? 64.911 112.208 52.484 0.90 22.06 ? 2512 GOL M C3 1 HETATM 4461 O O3 A GOL JA 10 . ? 65.102 113.137 51.426 0.55 8.34 ? 2512 GOL M O3 1 HETATM 4462 O O3 B GOL JA 10 . ? 64.460 112.174 53.819 0.35 15.27 ? 2512 GOL M O3 1 HETATM 4463 C C1 . GOL KA 10 . ? 32.593 103.158 75.413 0.87 30.87 ? 2513 GOL M C1 1 HETATM 4464 O O1 . GOL KA 10 . ? 33.020 101.973 76.025 0.87 37.29 ? 2513 GOL M O1 1 HETATM 4465 C C2 . GOL KA 10 . ? 32.505 104.403 76.316 0.87 28.28 ? 2513 GOL M C2 1 HETATM 4466 O O2 . GOL KA 10 . ? 31.459 104.327 77.288 0.87 14.08 ? 2513 GOL M O2 1 HETATM 4467 C C3 . GOL KA 10 . ? 33.844 104.814 76.929 0.87 27.99 ? 2513 GOL M C3 1 HETATM 4468 O O3 . GOL KA 10 . ? 33.752 106.180 77.416 0.87 20.98 ? 2513 GOL M O3 1 HETATM 4469 C C1 . GOL LA 10 . ? 34.499 117.605 75.039 0.88 41.09 ? 2514 GOL M C1 1 HETATM 4470 O O1 . GOL LA 10 . ? 35.043 118.053 76.267 0.88 45.12 ? 2514 GOL M O1 1 HETATM 4471 C C2 . GOL LA 10 . ? 34.574 116.091 74.925 0.88 45.63 ? 2514 GOL M C2 1 HETATM 4472 O O2 . GOL LA 10 . ? 35.331 115.775 73.751 0.88 46.32 ? 2514 GOL M O2 1 HETATM 4473 C C3 . GOL LA 10 . ? 33.186 115.397 75.004 0.88 37.67 ? 2514 GOL M C3 1 HETATM 4474 O O3 . GOL LA 10 . ? 32.158 115.725 74.076 0.88 45.57 ? 2514 GOL M O3 1 HETATM 4475 O O . HOH MA 11 . ? 20.280 131.019 51.521 1.00 37.33 ? 3001 HOH M O 1 HETATM 4476 O O . HOH MA 11 . ? 25.240 132.976 51.066 1.00 41.95 ? 3002 HOH M O 1 HETATM 4477 O O . HOH MA 11 . ? 23.759 133.418 49.024 1.00 49.75 ? 3003 HOH M O 1 HETATM 4478 O O . HOH MA 11 . ? 26.729 140.979 46.354 1.00 41.06 ? 3004 HOH M O 1 HETATM 4479 O O . HOH MA 11 . ? 29.556 130.580 36.212 1.00 41.48 ? 3005 HOH M O 1 HETATM 4480 O O . HOH MA 11 . ? 27.029 133.301 36.795 1.00 38.83 ? 3006 HOH M O 1 HETATM 4481 O O . HOH MA 11 . ? 23.151 127.931 45.505 1.00 25.98 ? 3007 HOH M O 1 HETATM 4482 O O . HOH MA 11 . ? 24.612 130.922 43.417 1.00 37.74 ? 3008 HOH M O 1 HETATM 4483 O O . HOH MA 11 . ? 37.593 136.257 40.618 1.00 11.44 ? 3009 HOH M O 1 HETATM 4484 O O . HOH MA 11 . ? 26.770 138.417 45.917 1.00 34.27 ? 3010 HOH M O 1 HETATM 4485 O O . HOH MA 11 . ? 27.473 132.325 49.836 1.00 21.29 ? 3011 HOH M O 1 HETATM 4486 O O . HOH MA 11 . ? 28.984 130.149 48.976 1.00 14.13 ? 3012 HOH M O 1 HETATM 4487 O O . HOH MA 11 . ? 34.409 140.311 56.124 1.00 32.82 ? 3013 HOH M O 1 HETATM 4488 O O . HOH MA 11 . ? 33.463 139.193 61.452 1.00 42.81 ? 3014 HOH M O 1 HETATM 4489 O O . HOH MA 11 . ? 30.393 140.598 55.210 1.00 52.96 ? 3015 HOH M O 1 HETATM 4490 O O . HOH MA 11 . ? 33.265 129.224 41.699 1.00 13.73 ? 3016 HOH M O 1 HETATM 4491 O O . HOH MA 11 . ? 31.466 127.352 43.008 1.00 11.98 ? 3017 HOH M O 1 HETATM 4492 O O . HOH MA 11 . ? 24.758 127.404 43.316 1.00 38.52 ? 3018 HOH M O 1 HETATM 4493 O O . HOH MA 11 . ? 28.806 125.692 39.270 1.00 34.40 ? 3019 HOH M O 1 HETATM 4494 O O . HOH MA 11 . ? 34.414 133.424 39.780 1.00 17.28 ? 3020 HOH M O 1 HETATM 4495 O O . HOH MA 11 . ? 28.366 131.569 38.224 1.00 37.90 ? 3021 HOH M O 1 HETATM 4496 O O . HOH MA 11 . ? 31.540 130.999 37.845 1.00 22.15 ? 3022 HOH M O 1 HETATM 4497 O O . HOH MA 11 . ? 24.338 125.253 67.763 1.00 39.05 ? 3023 HOH M O 1 HETATM 4498 O O . HOH MA 11 . ? 33.419 137.554 40.382 0.50 11.56 ? 3024 HOH M O 1 HETATM 4499 O O . HOH MA 11 . ? 29.068 138.264 41.601 1.00 20.09 ? 3025 HOH M O 1 HETATM 4500 O O . HOH MA 11 . ? 34.954 135.551 41.253 1.00 12.25 ? 3026 HOH M O 1 HETATM 4501 O O . HOH MA 11 . ? 29.069 123.334 70.194 1.00 33.24 ? 3027 HOH M O 1 HETATM 4502 O O . HOH MA 11 . ? 23.185 116.065 59.672 1.00 29.55 ? 3028 HOH M O 1 HETATM 4503 O O . HOH MA 11 . ? 29.798 125.354 68.285 1.00 33.61 ? 3029 HOH M O 1 HETATM 4504 O O . HOH MA 11 . ? 60.529 120.571 78.120 1.00 46.74 ? 3030 HOH M O 1 HETATM 4505 O O . HOH MA 11 . ? 62.777 120.970 76.580 1.00 29.32 ? 3031 HOH M O 1 HETATM 4506 O O . HOH MA 11 . ? 55.268 129.845 77.462 1.00 36.40 ? 3032 HOH M O 1 HETATM 4507 O O . HOH MA 11 . ? 25.379 135.137 51.927 1.00 43.16 ? 3033 HOH M O 1 HETATM 4508 O O . HOH MA 11 . ? 23.480 138.955 50.242 1.00 46.69 ? 3034 HOH M O 1 HETATM 4509 O O . HOH MA 11 . ? 25.125 139.799 54.187 1.00 38.44 ? 3035 HOH M O 1 HETATM 4510 O O . HOH MA 11 . ? 29.364 134.089 58.434 1.00 17.95 ? 3036 HOH M O 1 HETATM 4511 O O . HOH MA 11 . ? 33.035 139.356 57.952 1.00 33.52 ? 3037 HOH M O 1 HETATM 4512 O O . HOH MA 11 . ? 30.926 138.666 53.524 1.00 37.62 ? 3038 HOH M O 1 HETATM 4513 O O . HOH MA 11 . ? 28.443 141.545 58.951 1.00 55.72 ? 3039 HOH M O 1 HETATM 4514 O O . HOH MA 11 . ? 29.246 139.174 60.977 1.00 35.37 ? 3040 HOH M O 1 HETATM 4515 O O . HOH MA 11 . ? 58.160 96.562 72.091 1.00 39.10 ? 3041 HOH M O 1 HETATM 4516 O O . HOH MA 11 . ? 22.002 141.087 58.707 1.00 60.29 ? 3042 HOH M O 1 HETATM 4517 O O . HOH MA 11 . ? 20.849 133.119 55.735 1.00 45.54 ? 3043 HOH M O 1 HETATM 4518 O O . HOH MA 11 . ? 68.681 124.602 54.744 1.00 26.56 ? 3044 HOH M O 1 HETATM 4519 O O . HOH MA 11 . ? 25.401 128.076 67.506 1.00 30.87 ? 3045 HOH M O 1 HETATM 4520 O O . HOH MA 11 . ? 59.392 96.432 42.966 1.00 38.68 ? 3046 HOH M O 1 HETATM 4521 O O . HOH MA 11 . ? 60.551 121.645 44.060 1.00 32.90 ? 3047 HOH M O 1 HETATM 4522 O O . HOH MA 11 . ? 61.237 127.949 44.322 1.00 54.02 ? 3048 HOH M O 1 HETATM 4523 O O . HOH MA 11 . ? 59.433 134.464 56.747 1.00 44.70 ? 3049 HOH M O 1 HETATM 4524 O O . HOH MA 11 . ? 60.868 132.855 58.165 1.00 22.54 ? 3050 HOH M O 1 HETATM 4525 O O . HOH MA 11 . ? 64.237 130.263 56.656 1.00 43.74 ? 3051 HOH M O 1 HETATM 4526 O O . HOH MA 11 . ? 63.661 133.678 55.025 1.00 42.95 ? 3052 HOH M O 1 HETATM 4527 O O . HOH MA 11 . ? 69.593 128.731 53.467 1.00 42.17 ? 3053 HOH M O 1 HETATM 4528 O O . HOH MA 11 . ? 68.927 126.654 56.747 1.00 27.96 ? 3054 HOH M O 1 HETATM 4529 O O . HOH MA 11 . ? 24.806 120.176 60.414 1.00 18.00 ? 3055 HOH M O 1 HETATM 4530 O O . HOH MA 11 . ? 20.318 118.982 62.985 1.00 38.60 ? 3056 HOH M O 1 HETATM 4531 O O . HOH MA 11 . ? 25.865 123.878 65.507 1.00 23.17 ? 3057 HOH M O 1 HETATM 4532 O O . HOH MA 11 . ? 62.388 129.196 60.530 1.00 18.88 ? 3058 HOH M O 1 HETATM 4533 O O . HOH MA 11 . ? 20.213 120.321 65.819 1.00 32.26 ? 3059 HOH M O 1 HETATM 4534 O O . HOH MA 11 . ? 26.299 123.446 69.445 1.00 46.05 ? 3060 HOH M O 1 HETATM 4535 O O . HOH MA 11 . ? 64.370 125.115 69.401 1.00 32.94 ? 3061 HOH M O 1 HETATM 4536 O O . HOH MA 11 . ? 61.701 130.820 67.154 1.00 25.08 ? 3062 HOH M O 1 HETATM 4537 O O . HOH MA 11 . ? 22.588 117.720 66.817 1.00 38.43 ? 3063 HOH M O 1 HETATM 4538 O O . HOH MA 11 . ? 24.847 116.416 62.832 1.00 43.52 ? 3064 HOH M O 1 HETATM 4539 O O . HOH MA 11 . ? 29.110 116.843 69.384 1.00 35.90 ? 3065 HOH M O 1 HETATM 4540 O O . HOH MA 11 . ? 26.530 116.918 63.481 1.00 40.92 ? 3066 HOH M O 1 HETATM 4541 O O . HOH MA 11 . ? 29.549 116.233 65.565 1.00 20.53 ? 3067 HOH M O 1 HETATM 4542 O O . HOH MA 11 . ? 56.734 118.978 77.173 1.00 31.70 ? 3068 HOH M O 1 HETATM 4543 O O . HOH MA 11 . ? 59.309 122.512 77.334 1.00 40.04 ? 3069 HOH M O 1 HETATM 4544 O O . HOH MA 11 . ? 28.316 123.692 66.530 1.00 22.55 ? 3070 HOH M O 1 HETATM 4545 O O . HOH MA 11 . ? 63.320 123.905 76.097 1.00 33.72 ? 3071 HOH M O 1 HETATM 4546 O O . HOH MA 11 . ? 53.088 128.910 76.491 1.00 22.70 ? 3072 HOH M O 1 HETATM 4547 O O . HOH MA 11 . ? 52.865 125.538 79.146 1.00 20.68 ? 3073 HOH M O 1 HETATM 4548 O O . HOH MA 11 . ? 54.360 95.880 45.364 1.00 50.50 ? 3074 HOH M O 1 HETATM 4549 O O . HOH MA 11 . ? 49.976 118.995 64.886 1.00 7.54 ? 3075 HOH M O 1 HETATM 4550 O O . HOH MA 11 . ? 30.180 120.944 34.088 1.00 30.40 ? 3076 HOH M O 1 HETATM 4551 O O . HOH MA 11 . ? 63.410 120.213 59.889 1.00 9.03 ? 3077 HOH M O 1 HETATM 4552 O O . HOH MA 11 . ? 58.973 120.460 63.241 1.00 9.83 ? 3078 HOH M O 1 HETATM 4553 O O . HOH MA 11 . ? 61.025 116.785 75.404 1.00 22.75 ? 3079 HOH M O 1 HETATM 4554 O O . HOH MA 11 . ? 57.429 117.757 64.923 1.00 8.93 ? 3080 HOH M O 1 HETATM 4555 O O . HOH MA 11 . ? 51.528 118.262 67.193 1.00 10.39 ? 3081 HOH M O 1 HETATM 4556 O O . HOH MA 11 . ? 57.239 96.305 69.793 1.00 34.89 ? 3082 HOH M O 1 HETATM 4557 O O . HOH MA 11 . ? 56.244 96.617 37.208 1.00 36.59 ? 3083 HOH M O 1 HETATM 4558 O O . HOH MA 11 . ? 66.945 97.771 70.889 1.00 36.37 ? 3084 HOH M O 1 HETATM 4559 O O . HOH MA 11 . ? 64.122 102.043 76.629 1.00 42.60 ? 3085 HOH M O 1 HETATM 4560 O O . HOH MA 11 . ? 65.011 106.632 71.670 1.00 14.85 ? 3086 HOH M O 1 HETATM 4561 O O . HOH MA 11 . ? 65.874 122.556 67.226 1.00 37.01 ? 3087 HOH M O 1 HETATM 4562 O O . HOH MA 11 . ? 63.216 109.002 79.956 1.00 38.88 ? 3088 HOH M O 1 HETATM 4563 O O . HOH MA 11 . ? 60.097 117.655 77.712 1.00 31.23 ? 3089 HOH M O 1 HETATM 4564 O O . HOH MA 11 . ? 49.959 120.316 81.857 1.00 39.78 ? 3090 HOH M O 1 HETATM 4565 O O . HOH MA 11 . ? 64.935 104.221 31.855 1.00 48.88 ? 3091 HOH M O 1 HETATM 4566 O O . HOH MA 11 . ? 66.736 110.540 64.973 1.00 16.09 ? 3092 HOH M O 1 HETATM 4567 O O . HOH MA 11 . ? 43.923 121.649 81.820 1.00 69.22 ? 3093 HOH M O 1 HETATM 4568 O O . HOH MA 11 . ? 41.763 123.842 81.430 1.00 43.85 ? 3094 HOH M O 1 HETATM 4569 O O . HOH MA 11 . ? 38.309 119.986 83.411 1.00 52.04 ? 3095 HOH M O 1 HETATM 4570 O O . HOH MA 11 . ? 33.978 112.494 72.087 1.00 30.79 ? 3096 HOH M O 1 HETATM 4571 O O . HOH MA 11 . ? 69.246 114.851 54.799 1.00 14.68 ? 3097 HOH M O 1 HETATM 4572 O O . HOH MA 11 . ? 56.178 108.240 53.831 1.00 9.98 ? 3098 HOH M O 1 HETATM 4573 O O . HOH MA 11 . ? 30.956 93.734 43.302 1.00 45.77 ? 3099 HOH M O 1 HETATM 4574 O O . HOH MA 11 . ? 65.960 123.818 54.497 1.00 16.81 ? 3100 HOH M O 1 HETATM 4575 O O . HOH MA 11 . ? 71.587 114.855 47.190 1.00 18.74 ? 3101 HOH M O 1 HETATM 4576 O O . HOH MA 11 . ? 72.095 108.855 47.813 1.00 10.50 ? 3102 HOH M O 1 HETATM 4577 O O . HOH MA 11 . ? 69.391 108.324 50.731 1.00 12.79 ? 3103 HOH M O 1 HETATM 4578 O O . HOH MA 11 . ? 60.657 98.411 45.168 1.00 29.84 ? 3104 HOH M O 1 HETATM 4579 O O . HOH MA 11 . ? 53.524 92.722 57.475 1.00 34.80 ? 3105 HOH M O 1 HETATM 4580 O O . HOH MA 11 . ? 54.209 91.964 55.159 1.00 54.42 ? 3106 HOH M O 1 HETATM 4581 O O . HOH MA 11 . ? 63.014 123.166 43.712 1.00 43.38 ? 3107 HOH M O 1 HETATM 4582 O O . HOH MA 11 . ? 66.734 119.939 44.880 1.00 26.77 ? 3108 HOH M O 1 HETATM 4583 O O . HOH MA 11 . ? 64.614 122.062 42.289 1.00 59.43 ? 3109 HOH M O 1 HETATM 4584 O O . HOH MA 11 . ? 60.557 125.165 46.753 1.00 36.84 ? 3110 HOH M O 1 HETATM 4585 O O . HOH MA 11 . ? 68.766 122.560 47.039 1.00 24.56 ? 3111 HOH M O 1 HETATM 4586 O O . HOH MA 11 . ? 63.560 127.140 45.700 1.00 37.47 ? 3112 HOH M O 1 HETATM 4587 O O . HOH MA 11 . ? 64.607 114.666 45.764 1.00 14.56 ? 3113 HOH M O 1 HETATM 4588 O O . HOH MA 11 . ? 43.825 108.532 80.275 1.00 43.95 ? 3114 HOH M O 1 HETATM 4589 O O . HOH MA 11 . ? 66.099 130.776 49.534 1.00 50.86 ? 3115 HOH M O 1 HETATM 4590 O O . HOH MA 11 . ? 61.558 133.450 49.112 1.00 33.39 ? 3116 HOH M O 1 HETATM 4591 O O . HOH MA 11 . ? 59.829 133.509 53.731 1.00 24.57 ? 3117 HOH M O 1 HETATM 4592 O O . HOH MA 11 . ? 62.080 131.728 55.995 1.00 27.21 ? 3118 HOH M O 1 HETATM 4593 O O . HOH MA 11 . ? 38.657 110.572 80.697 1.00 43.81 ? 3119 HOH M O 1 HETATM 4594 O O . HOH MA 11 . ? 33.332 110.240 71.105 1.00 36.73 ? 3120 HOH M O 1 HETATM 4595 O O . HOH MA 11 . ? 66.669 127.900 55.945 1.00 39.24 ? 3121 HOH M O 1 HETATM 4596 O O . HOH MA 11 . ? 71.592 127.278 50.163 1.00 54.67 ? 3122 HOH M O 1 HETATM 4597 O O . HOH MA 11 . ? 69.676 126.576 52.633 1.00 24.24 ? 3123 HOH M O 1 HETATM 4598 O O . HOH MA 11 . ? 65.446 126.650 60.077 1.00 17.64 ? 3124 HOH M O 1 HETATM 4599 O O . HOH MA 11 . ? 63.531 127.864 58.384 1.00 16.07 ? 3125 HOH M O 1 HETATM 4600 O O . HOH MA 11 . ? 61.911 126.719 61.293 1.00 11.04 ? 3126 HOH M O 1 HETATM 4601 O O . HOH MA 11 . ? 48.122 115.352 37.627 1.00 48.81 ? 3127 HOH M O 1 HETATM 4602 O O . HOH MA 11 . ? 68.269 125.396 62.384 1.00 17.98 ? 3128 HOH M O 1 HETATM 4603 O O . HOH MA 11 . ? 63.191 123.287 67.692 1.00 14.38 ? 3129 HOH M O 1 HETATM 4604 O O . HOH MA 11 . ? 65.141 127.621 62.711 1.00 19.54 ? 3130 HOH M O 1 HETATM 4605 O O . HOH MA 11 . ? 56.397 115.273 37.888 1.00 30.98 ? 3131 HOH M O 1 HETATM 4606 O O . HOH MA 11 . ? 57.108 119.081 39.170 1.00 42.19 ? 3132 HOH M O 1 HETATM 4607 O O . HOH MA 11 . ? 60.929 129.925 64.509 1.00 17.15 ? 3133 HOH M O 1 HETATM 4608 O O . HOH MA 11 . ? 60.821 128.888 73.375 1.00 33.71 ? 3134 HOH M O 1 HETATM 4609 O O . HOH MA 11 . ? 60.514 124.668 68.179 1.00 22.00 ? 3135 HOH M O 1 HETATM 4610 O O . HOH MA 11 . ? 60.680 130.005 69.858 1.00 33.10 ? 3136 HOH M O 1 HETATM 4611 O O . HOH MA 11 . ? 62.680 126.405 71.611 1.00 43.31 ? 3137 HOH M O 1 HETATM 4612 O O . HOH MA 11 . ? 68.220 106.702 40.214 1.00 35.80 ? 3138 HOH M O 1 HETATM 4613 O O . HOH MA 11 . ? 61.084 120.130 41.886 1.00 33.32 ? 3139 HOH M O 1 HETATM 4614 O O . HOH MA 11 . ? 56.926 121.525 76.162 1.00 23.37 ? 3140 HOH M O 1 HETATM 4615 O O . HOH MA 11 . ? 52.945 126.097 76.396 1.00 14.22 ? 3141 HOH M O 1 HETATM 4616 O O . HOH MA 11 . ? 56.723 125.331 77.511 1.00 38.51 ? 3142 HOH M O 1 HETATM 4617 O O . HOH MA 11 . ? 61.018 124.601 75.219 1.00 38.14 ? 3143 HOH M O 1 HETATM 4618 O O . HOH MA 11 . ? 54.560 119.697 78.129 1.00 39.02 ? 3144 HOH M O 1 HETATM 4619 O O . HOH MA 11 . ? 55.481 122.867 78.464 1.00 38.16 ? 3145 HOH M O 1 HETATM 4620 O O . HOH MA 11 . ? 58.727 97.394 40.656 1.00 27.60 ? 3146 HOH M O 1 HETATM 4621 O O . HOH MA 11 . ? 43.849 126.521 78.898 1.00 25.34 ? 3147 HOH M O 1 HETATM 4622 O O . HOH MA 11 . ? 50.238 125.385 80.406 1.00 22.34 ? 3148 HOH M O 1 HETATM 4623 O O . HOH MA 11 . ? 46.408 123.465 79.625 1.00 26.54 ? 3149 HOH M O 1 HETATM 4624 O O . HOH MA 11 . ? 49.657 134.669 75.703 1.00 48.88 ? 3150 HOH M O 1 HETATM 4625 O O . HOH MA 11 . ? 51.450 129.977 78.195 1.00 33.26 ? 3151 HOH M O 1 HETATM 4626 O O . HOH MA 11 . ? 47.332 132.362 72.269 1.00 21.34 ? 3152 HOH M O 1 HETATM 4627 O O . HOH MA 11 . ? 52.925 94.420 46.654 1.00 44.20 ? 3153 HOH M O 1 HETATM 4628 O O . HOH MA 11 . ? 55.739 92.656 49.047 1.00 49.23 ? 3154 HOH M O 1 HETATM 4629 O O . HOH MA 11 . ? 52.509 92.999 52.811 1.00 36.22 ? 3155 HOH M O 1 HETATM 4630 O O . HOH MA 11 . ? 50.641 126.535 66.287 1.00 23.00 ? 3156 HOH M O 1 HETATM 4631 O O . HOH MA 11 . ? 43.084 128.241 77.159 1.00 28.10 ? 3157 HOH M O 1 HETATM 4632 O O . HOH MA 11 . ? 48.913 131.267 77.927 1.00 31.46 ? 3158 HOH M O 1 HETATM 4633 O O . HOH MA 11 . ? 45.741 130.142 79.365 1.00 46.06 ? 3159 HOH M O 1 HETATM 4634 O O . HOH MA 11 . ? 42.010 132.120 75.398 1.00 32.46 ? 3160 HOH M O 1 HETATM 4635 O O . HOH MA 11 . ? 47.821 133.079 74.840 1.00 35.02 ? 3161 HOH M O 1 HETATM 4636 O O . HOH MA 11 . ? 48.746 93.197 55.364 1.00 39.47 ? 3162 HOH M O 1 HETATM 4637 O O . HOH MA 11 . ? 42.170 86.403 63.169 1.00 52.47 ? 3163 HOH M O 1 HETATM 4638 O O . HOH MA 11 . ? 37.957 126.432 75.227 1.00 68.16 ? 3164 HOH M O 1 HETATM 4639 O O . HOH MA 11 . ? 36.132 127.911 74.795 1.00 36.68 ? 3165 HOH M O 1 HETATM 4640 O O . HOH MA 11 . ? 35.411 132.420 73.391 1.00 33.15 ? 3166 HOH M O 1 HETATM 4641 O O . HOH MA 11 . ? 44.488 133.530 72.504 1.00 41.90 ? 3167 HOH M O 1 HETATM 4642 O O . HOH MA 11 . ? 39.386 137.069 71.389 1.00 41.61 ? 3168 HOH M O 1 HETATM 4643 O O . HOH MA 11 . ? 28.142 109.496 64.574 1.00 23.79 ? 3169 HOH M O 1 HETATM 4644 O O . HOH MA 11 . ? 33.320 131.753 69.383 1.00 16.33 ? 3170 HOH M O 1 HETATM 4645 O O . HOH MA 11 . ? 31.288 126.309 70.865 1.00 20.55 ? 3171 HOH M O 1 HETATM 4646 O O . HOH MA 11 . ? 28.615 114.649 37.791 1.00 43.83 ? 3172 HOH M O 1 HETATM 4647 O O . HOH MA 11 . ? 28.200 120.696 38.635 1.00 37.76 ? 3173 HOH M O 1 HETATM 4648 O O . HOH MA 11 . ? 32.570 125.020 68.086 1.00 28.20 ? 3174 HOH M O 1 HETATM 4649 O O . HOH MA 11 . ? 31.670 123.218 33.453 1.00 25.14 ? 3175 HOH M O 1 HETATM 4650 O O . HOH MA 11 . ? 29.966 115.403 32.988 1.00 46.02 ? 3176 HOH M O 1 HETATM 4651 O O . HOH MA 11 . ? 49.112 122.305 69.049 1.00 13.32 ? 3177 HOH M O 1 HETATM 4652 O O . HOH MA 11 . ? 48.572 124.751 65.603 1.00 18.93 ? 3178 HOH M O 1 HETATM 4653 O O . HOH MA 11 . ? 40.745 118.642 24.489 1.00 37.86 ? 3179 HOH M O 1 HETATM 4654 O O . HOH MA 11 . ? 36.723 104.971 32.173 1.00 43.70 ? 3180 HOH M O 1 HETATM 4655 O O . HOH MA 11 . ? 29.552 107.937 39.548 1.00 34.47 ? 3181 HOH M O 1 HETATM 4656 O O . HOH MA 11 . ? 42.672 105.699 29.655 1.00 39.57 ? 3182 HOH M O 1 HETATM 4657 O O . HOH MA 11 . ? 40.309 104.680 29.164 1.00 39.62 ? 3183 HOH M O 1 HETATM 4658 O O . HOH MA 11 . ? 28.194 113.216 41.377 1.00 18.66 ? 3184 HOH M O 1 HETATM 4659 O O . HOH MA 11 . ? 35.266 101.435 43.399 1.00 15.06 ? 3185 HOH M O 1 HETATM 4660 O O . HOH MA 11 . ? 58.022 112.397 63.183 1.00 10.42 ? 3186 HOH M O 1 HETATM 4661 O O . HOH MA 11 . ? 59.484 115.652 73.266 1.00 13.40 ? 3187 HOH M O 1 HETATM 4662 O O . HOH MA 11 . ? 29.397 98.054 50.691 1.00 48.77 ? 3188 HOH M O 1 HETATM 4663 O O . HOH MA 11 . ? 32.793 96.171 54.336 1.00 39.26 ? 3189 HOH M O 1 HETATM 4664 O O . HOH MA 11 . ? 35.066 90.920 48.761 1.00 46.75 ? 3190 HOH M O 1 HETATM 4665 O O . HOH MA 11 . ? 39.925 90.884 43.767 1.00 52.67 ? 3191 HOH M O 1 HETATM 4666 O O . HOH MA 11 . ? 41.070 93.289 41.620 1.00 23.87 ? 3192 HOH M O 1 HETATM 4667 O O . HOH MA 11 . ? 63.128 109.708 64.419 1.00 14.67 ? 3193 HOH M O 1 HETATM 4668 O O . HOH MA 11 . ? 46.036 93.408 35.560 1.00 39.18 ? 3194 HOH M O 1 HETATM 4669 O O . HOH MA 11 . ? 40.914 98.184 28.506 1.00 47.87 ? 3195 HOH M O 1 HETATM 4670 O O . HOH MA 11 . ? 38.587 93.912 31.118 1.00 54.23 ? 3196 HOH M O 1 HETATM 4671 O O . HOH MA 11 . ? 38.708 96.737 28.351 1.00 50.78 ? 3197 HOH M O 1 HETATM 4672 O O . HOH MA 11 . ? 70.253 99.216 70.082 1.00 38.39 ? 3198 HOH M O 1 HETATM 4673 O O . HOH MA 11 . ? 45.537 94.370 39.153 1.00 28.96 ? 3199 HOH M O 1 HETATM 4674 O O . HOH MA 11 . ? 56.147 97.526 39.726 1.00 29.40 ? 3200 HOH M O 1 HETATM 4675 O O . HOH MA 11 . ? 59.161 96.939 67.615 1.00 18.11 ? 3201 HOH M O 1 HETATM 4676 O O . HOH MA 11 . ? 39.507 88.717 47.305 1.00 42.40 ? 3202 HOH M O 1 HETATM 4677 O O . HOH MA 11 . ? 59.420 99.936 73.748 1.00 25.65 ? 3203 HOH M O 1 HETATM 4678 O O . HOH MA 11 . ? 40.913 86.920 55.451 1.00 36.38 ? 3204 HOH M O 1 HETATM 4679 O O . HOH MA 11 . ? 46.387 90.813 55.252 1.00 36.67 ? 3205 HOH M O 1 HETATM 4680 O O . HOH MA 11 . ? 62.607 95.995 73.562 1.00 42.60 ? 3206 HOH M O 1 HETATM 4681 O O . HOH MA 11 . ? 64.988 96.513 69.297 1.00 23.58 ? 3207 HOH M O 1 HETATM 4682 O O . HOH MA 11 . ? 63.988 99.458 74.741 1.00 43.00 ? 3208 HOH M O 1 HETATM 4683 O O . HOH MA 11 . ? 65.648 104.396 73.012 1.00 21.43 ? 3209 HOH M O 1 HETATM 4684 O O . HOH MA 11 . ? 66.096 101.104 74.258 1.00 37.54 ? 3210 HOH M O 1 HETATM 4685 O O . HOH MA 11 . ? 30.940 103.136 57.361 1.00 27.36 ? 3211 HOH M O 1 HETATM 4686 O O . HOH MA 11 . ? 28.357 105.610 59.086 1.00 22.65 ? 3212 HOH M O 1 HETATM 4687 O O . HOH MA 11 . ? 28.198 106.108 61.797 1.00 31.80 ? 3213 HOH M O 1 HETATM 4688 O O . HOH MA 11 . ? 63.104 105.205 70.132 1.00 12.03 ? 3214 HOH M O 1 HETATM 4689 O O . HOH MA 11 . ? 64.193 104.961 75.374 1.00 20.87 ? 3215 HOH M O 1 HETATM 4690 O O . HOH MA 11 . ? 61.697 102.987 76.499 1.00 23.40 ? 3216 HOH M O 1 HETATM 4691 O O . HOH MA 11 . ? 61.600 105.147 78.181 1.00 27.65 ? 3217 HOH M O 1 HETATM 4692 O O . HOH MA 11 . ? 64.171 111.435 76.219 1.00 21.19 ? 3218 HOH M O 1 HETATM 4693 O O . HOH MA 11 . ? 62.289 114.539 74.967 1.00 34.76 ? 3219 HOH M O 1 HETATM 4694 O O . HOH MA 11 . ? 59.014 104.896 79.309 1.00 36.99 ? 3220 HOH M O 1 HETATM 4695 O O . HOH MA 11 . ? 62.323 107.944 77.718 1.00 15.31 ? 3221 HOH M O 1 HETATM 4696 O O . HOH MA 11 . ? 44.844 125.890 29.407 1.00 29.22 ? 3222 HOH M O 1 HETATM 4697 O O . HOH MA 11 . ? 57.640 116.523 78.122 1.00 31.30 ? 3223 HOH M O 1 HETATM 4698 O O . HOH MA 11 . ? 62.150 110.977 78.555 1.00 29.33 ? 3224 HOH M O 1 HETATM 4699 O O . HOH MA 11 . ? 52.705 110.678 24.129 1.00 39.26 ? 3225 HOH M O 1 HETATM 4700 O O . HOH MA 11 . ? 51.952 115.368 80.809 1.00 45.97 ? 3226 HOH M O 1 HETATM 4701 O O . HOH MA 11 . ? 52.437 112.749 81.940 1.00 46.44 ? 3227 HOH M O 1 HETATM 4702 O O . HOH MA 11 . ? 66.045 106.854 32.947 1.00 30.53 ? 3228 HOH M O 1 HETATM 4703 O O . HOH MA 11 . ? 55.923 114.848 35.184 1.00 34.07 ? 3229 HOH M O 1 HETATM 4704 O O . HOH MA 11 . ? 51.182 120.312 69.089 1.00 13.11 ? 3230 HOH M O 1 HETATM 4705 O O . HOH MA 11 . ? 52.337 119.506 76.576 1.00 22.87 ? 3231 HOH M O 1 HETATM 4706 O O . HOH MA 11 . ? 50.460 114.127 34.544 1.00 36.92 ? 3232 HOH M O 1 HETATM 4707 O O . HOH MA 11 . ? 52.435 115.393 37.841 1.00 51.67 ? 3233 HOH M O 1 HETATM 4708 O O . HOH MA 11 . ? 48.101 112.021 81.288 1.00 44.39 ? 3234 HOH M O 1 HETATM 4709 O O . HOH MA 11 . ? 46.284 111.249 77.053 1.00 23.53 ? 3235 HOH M O 1 HETATM 4710 O O . HOH MA 11 . ? 46.890 124.565 35.797 1.00 24.79 ? 3236 HOH M O 1 HETATM 4711 O O . HOH MA 11 . ? 47.844 125.108 32.049 1.00 41.70 ? 3237 HOH M O 1 HETATM 4712 O O . HOH MA 11 . ? 47.701 120.155 80.347 1.00 20.99 ? 3238 HOH M O 1 HETATM 4713 O O . HOH MA 11 . ? 45.497 126.674 31.922 1.00 20.30 ? 3239 HOH M O 1 HETATM 4714 O O . HOH MA 11 . ? 43.658 127.571 27.727 1.00 38.41 ? 3240 HOH M O 1 HETATM 4715 O O . HOH MA 11 . ? 31.616 132.007 25.291 1.00 45.95 ? 3241 HOH M O 1 HETATM 4716 O O . HOH MA 11 . ? 33.107 132.454 29.652 1.00 34.82 ? 3242 HOH M O 1 HETATM 4717 O O . HOH MA 11 . ? 46.149 113.163 78.472 1.00 29.59 ? 3243 HOH M O 1 HETATM 4718 O O . HOH MA 11 . ? 44.077 114.257 80.151 1.00 45.91 ? 3244 HOH M O 1 HETATM 4719 O O . HOH MA 11 . ? 38.807 135.561 33.340 1.00 17.84 ? 3245 HOH M O 1 HETATM 4720 O O . HOH MA 11 . ? 45.877 136.313 35.924 1.00 45.88 ? 3246 HOH M O 1 HETATM 4721 O O . HOH MA 11 . ? 33.615 133.205 32.003 1.00 30.79 ? 3247 HOH M O 1 HETATM 4722 O O . HOH MA 11 . ? 43.509 123.828 79.170 1.00 21.12 ? 3248 HOH M O 1 HETATM 4723 O O . HOH MA 11 . ? 40.246 135.989 37.477 1.00 27.10 ? 3249 HOH M O 1 HETATM 4724 O O . HOH MA 11 . ? 41.783 137.967 40.988 1.00 23.61 ? 3250 HOH M O 1 HETATM 4725 O O . HOH MA 11 . ? 40.696 137.845 45.467 1.00 37.43 ? 3251 HOH M O 1 HETATM 4726 O O . HOH MA 11 . ? 35.693 119.405 79.386 1.00 39.48 ? 3252 HOH M O 1 HETATM 4727 O O . HOH MA 11 . ? 47.991 136.655 45.818 1.00 41.01 ? 3253 HOH M O 1 HETATM 4728 O O . HOH MA 11 . ? 40.271 122.229 82.548 1.00 43.03 ? 3254 HOH M O 1 HETATM 4729 O O . HOH MA 11 . ? 35.489 123.520 79.252 1.00 33.10 ? 3255 HOH M O 1 HETATM 4730 O O . HOH MA 11 . ? 36.609 121.378 82.135 1.00 48.86 ? 3256 HOH M O 1 HETATM 4731 O O . HOH MA 11 . ? 53.216 136.877 34.039 1.00 35.30 ? 3257 HOH M O 1 HETATM 4732 O O . HOH MA 11 . ? 33.170 115.242 70.937 1.00 29.42 ? 3258 HOH M O 1 HETATM 4733 O O . HOH MA 11 . ? 33.964 119.108 72.292 1.00 23.79 ? 3259 HOH M O 1 HETATM 4734 O O . HOH MA 11 . ? 28.966 121.958 36.402 1.00 43.39 ? 3260 HOH M O 1 HETATM 4735 O O . HOH MA 11 . ? 38.769 112.770 70.845 1.00 12.49 ? 3261 HOH M O 1 HETATM 4736 O O . HOH MA 11 . ? 24.619 123.233 44.607 1.00 36.84 ? 3262 HOH M O 1 HETATM 4737 O O . HOH MA 11 . ? 47.221 116.388 61.289 1.00 10.37 ? 3263 HOH M O 1 HETATM 4738 O O . HOH MA 11 . ? 25.853 113.886 40.048 1.00 43.30 ? 3264 HOH M O 1 HETATM 4739 O O . HOH MA 11 . ? 24.895 103.042 48.512 1.00 38.31 ? 3265 HOH M O 1 HETATM 4740 O O . HOH MA 11 . ? 24.728 103.234 51.127 1.00 37.17 ? 3266 HOH M O 1 HETATM 4741 O O . HOH MA 11 . ? 28.082 108.784 42.112 1.00 32.98 ? 3267 HOH M O 1 HETATM 4742 O O . HOH MA 11 . ? 29.847 98.857 42.837 1.00 49.33 ? 3268 HOH M O 1 HETATM 4743 O O . HOH MA 11 . ? 49.882 118.436 54.530 1.00 25.87 ? 3269 HOH M O 1 HETATM 4744 O O . HOH MA 11 . ? 53.556 116.800 59.987 1.00 9.86 ? 3270 HOH M O 1 HETATM 4745 O O . HOH MA 11 . ? 30.187 96.481 43.594 1.00 52.08 ? 3271 HOH M O 1 HETATM 4746 O O . HOH MA 11 . ? 55.878 110.966 54.028 1.00 10.59 ? 3272 HOH M O 1 HETATM 4747 O O . HOH MA 11 . ? 28.947 112.174 67.165 1.00 41.35 ? 3273 HOH M O 1 HETATM 4748 O O . HOH MA 11 . ? 52.376 113.291 62.282 1.00 9.49 ? 3274 HOH M O 1 HETATM 4749 O O . HOH MA 11 . ? 57.691 116.023 62.728 1.00 9.76 ? 3275 HOH M O 1 HETATM 4750 O O . HOH MA 11 . ? 54.200 110.595 62.492 1.00 9.59 ? 3276 HOH M O 1 HETATM 4751 O O . HOH MA 11 . ? 57.602 135.171 50.197 1.00 43.12 ? 3277 HOH M O 1 HETATM 4752 O O . HOH MA 11 . ? 55.228 136.639 46.595 1.00 54.75 ? 3278 HOH M O 1 HETATM 4753 O O . HOH MA 11 . ? 45.566 137.030 48.150 1.00 61.32 ? 3279 HOH M O 1 HETATM 4754 O O . HOH MA 11 . ? 51.864 139.954 48.274 1.00 33.59 ? 3280 HOH M O 1 HETATM 4755 O O . HOH MA 11 . ? 45.264 145.506 53.062 1.00 32.86 ? 3281 HOH M O 1 HETATM 4756 O O . HOH MA 11 . ? 70.531 108.609 58.583 1.00 13.72 ? 3282 HOH M O 1 HETATM 4757 O O . HOH MA 11 . ? 69.365 108.957 53.456 1.00 18.65 ? 3283 HOH M O 1 HETATM 4758 O O . HOH MA 11 . ? 64.204 96.855 60.116 1.00 44.10 ? 3284 HOH M O 1 HETATM 4759 O O . HOH MA 11 . ? 67.975 97.491 59.725 1.00 35.09 ? 3285 HOH M O 1 HETATM 4760 O O . HOH MA 11 . ? 66.951 97.097 53.670 1.00 34.91 ? 3286 HOH M O 1 HETATM 4761 O O . HOH MA 11 . ? 62.721 99.113 49.768 1.00 37.18 ? 3287 HOH M O 1 HETATM 4762 O O . HOH MA 11 . ? 66.927 106.927 52.090 1.00 16.21 ? 3288 HOH M O 1 HETATM 4763 O O . HOH MA 11 . ? 23.505 130.270 54.572 1.00 44.71 ? 3289 HOH M O 1 HETATM 4764 O O . HOH MA 11 . ? 19.784 118.749 57.545 1.00 40.01 ? 3290 HOH M O 1 HETATM 4765 O O . HOH MA 11 . ? 59.422 97.618 47.318 1.00 21.86 ? 3291 HOH M O 1 HETATM 4766 O O . HOH MA 11 . ? 61.817 97.265 49.358 1.00 34.48 ? 3292 HOH M O 1 HETATM 4767 O O . HOH MA 11 . ? 60.690 93.430 53.143 1.00 30.05 ? 3293 HOH M O 1 HETATM 4768 O O . HOH MA 11 . ? 55.493 94.541 58.090 1.00 14.58 ? 3294 HOH M O 1 HETATM 4769 O O . HOH MA 11 . ? 61.240 96.083 60.224 1.00 35.01 ? 3295 HOH M O 1 HETATM 4770 O O . HOH MA 11 . ? 63.904 95.348 53.307 1.00 40.05 ? 3296 HOH M O 1 HETATM 4771 O O . HOH MA 11 . ? 64.793 95.517 55.797 1.00 32.75 ? 3297 HOH M O 1 HETATM 4772 O O . HOH MA 11 . ? 57.651 92.639 55.717 1.00 32.69 ? 3298 HOH M O 1 HETATM 4773 O O . HOH MA 11 . ? 58.685 95.459 60.065 1.00 19.97 ? 3299 HOH M O 1 HETATM 4774 O O . HOH MA 11 . ? 64.782 96.114 57.825 1.00 35.37 ? 3300 HOH M O 1 HETATM 4775 O O . HOH MA 11 . ? 57.758 93.017 58.997 1.00 28.84 ? 3301 HOH M O 1 HETATM 4776 O O . HOH MA 11 . ? 58.627 95.364 62.885 1.00 32.70 ? 3302 HOH M O 1 HETATM 4777 O O . HOH MA 11 . ? 57.331 101.123 65.749 1.00 11.40 ? 3303 HOH M O 1 HETATM 4778 O O . HOH MA 11 . ? 61.053 96.595 62.834 1.00 51.06 ? 3304 HOH M O 1 HETATM 4779 O O . HOH MA 11 . ? 62.765 99.053 61.697 1.00 20.19 ? 3305 HOH M O 1 HETATM 4780 O O . HOH MA 11 . ? 56.306 128.514 45.625 1.00 51.31 ? 3306 HOH M O 1 HETATM 4781 O O . HOH MA 11 . ? 57.998 132.805 46.558 1.00 36.95 ? 3307 HOH M O 1 HETATM 4782 O O . HOH MA 11 . ? 51.353 96.039 67.936 1.00 38.47 ? 3308 HOH M O 1 HETATM 4783 O O . HOH MA 11 . ? 56.924 94.320 65.029 1.00 46.72 ? 3309 HOH M O 1 HETATM 4784 O O . HOH MA 11 . ? 58.145 97.985 65.397 1.00 22.40 ? 3310 HOH M O 1 HETATM 4785 O O . HOH MA 11 . ? 60.241 131.029 60.323 1.00 17.14 ? 3311 HOH M O 1 HETATM 4786 O O . HOH MA 11 . ? 59.090 137.463 58.549 1.00 53.54 ? 3312 HOH M O 1 HETATM 4787 O O . HOH MA 11 . ? 50.707 96.239 73.091 1.00 34.84 ? 3313 HOH M O 1 HETATM 4788 O O . HOH MA 11 . ? 47.568 95.661 71.064 1.00 29.45 ? 3314 HOH M O 1 HETATM 4789 O O . HOH MA 11 . ? 53.017 96.913 69.505 1.00 39.72 ? 3315 HOH M O 1 HETATM 4790 O O . HOH MA 11 . ? 49.574 94.532 69.039 1.00 44.84 ? 3316 HOH M O 1 HETATM 4791 O O . HOH MA 11 . ? 36.131 141.297 58.909 1.00 28.03 ? 3317 HOH M O 1 HETATM 4792 O O . HOH MA 11 . ? 45.755 101.978 77.912 1.00 38.56 ? 3318 HOH M O 1 HETATM 4793 O O . HOH MA 11 . ? 45.066 105.633 77.193 1.00 21.94 ? 3319 HOH M O 1 HETATM 4794 O O . HOH MA 11 . ? 52.732 107.488 79.860 1.00 39.07 ? 3320 HOH M O 1 HETATM 4795 O O . HOH MA 11 . ? 48.399 106.690 79.597 1.00 38.65 ? 3321 HOH M O 1 HETATM 4796 O O . HOH MA 11 . ? 44.911 108.710 77.756 1.00 30.11 ? 3322 HOH M O 1 HETATM 4797 O O . HOH MA 11 . ? 37.956 109.858 78.629 1.00 36.91 ? 3323 HOH M O 1 HETATM 4798 O O . HOH MA 11 . ? 42.703 102.325 77.670 1.00 29.62 ? 3324 HOH M O 1 HETATM 4799 O O . HOH MA 11 . ? 38.056 113.342 74.098 1.00 52.64 ? 3325 HOH M O 1 HETATM 4800 O O . HOH MA 11 . ? 34.253 108.926 68.667 1.00 19.77 ? 3326 HOH M O 1 HETATM 4801 O O . HOH MA 11 . ? 38.655 104.782 77.464 1.00 28.66 ? 3327 HOH M O 1 HETATM 4802 O O . HOH MA 11 . ? 32.041 113.690 69.708 1.00 40.55 ? 3328 HOH M O 1 HETATM 4803 O O . HOH MA 11 . ? 31.677 109.613 67.295 1.00 36.70 ? 3329 HOH M O 1 HETATM 4804 O O . HOH MA 11 . ? 50.175 110.193 51.674 1.00 12.40 ? 3330 HOH M O 1 HETATM 4805 O O . HOH MA 11 . ? 45.957 111.287 39.415 1.00 31.67 ? 3331 HOH M O 1 HETATM 4806 O O . HOH MA 11 . ? 49.116 114.774 40.979 1.00 28.09 ? 3332 HOH M O 1 HETATM 4807 O O . HOH MA 11 . ? 43.742 110.829 49.274 1.00 8.53 ? 3333 HOH M O 1 HETATM 4808 O O . HOH MA 11 . ? 51.802 120.960 43.599 1.00 70.28 ? 3334 HOH M O 1 HETATM 4809 O O . HOH MA 11 . ? 58.174 106.551 53.005 1.00 9.12 ? 3335 HOH M O 1 HETATM 4810 O O . HOH MA 11 . ? 58.867 116.729 39.253 1.00 24.77 ? 3336 HOH M O 1 HETATM 4811 O O . HOH MA 11 . ? 53.140 115.948 42.072 1.00 22.73 ? 3337 HOH M O 1 HETATM 4812 O O . HOH MA 11 . ? 59.313 120.863 46.604 1.00 18.17 ? 3338 HOH M O 1 HETATM 4813 O O . HOH MA 11 . ? 53.725 114.175 50.747 1.00 12.58 ? 3339 HOH M O 1 HETATM 4814 O O . HOH MA 11 . ? 55.885 113.370 52.358 1.00 9.02 ? 3340 HOH M O 1 HETATM 4815 O O . HOH MA 11 . ? 66.394 108.630 40.420 1.00 14.94 ? 3341 HOH M O 1 HETATM 4816 O O . HOH MA 11 . ? 68.739 112.141 34.811 1.00 36.55 ? 3342 HOH M O 1 HETATM 4817 O O . HOH MA 11 . ? 61.190 117.417 41.945 1.00 21.73 ? 3343 HOH M O 1 HETATM 4818 O O . HOH MA 11 . ? 69.866 110.857 38.468 1.00 32.26 ? 3344 HOH M O 1 HETATM 4819 O O . HOH MA 11 . ? 71.073 112.715 42.192 1.00 41.49 ? 3345 HOH M O 1 HETATM 4820 O O . HOH MA 11 . ? 65.454 119.555 42.322 1.00 35.33 ? 3346 HOH M O 1 HETATM 4821 O O . HOH MA 11 . ? 70.178 113.214 45.544 1.00 17.02 ? 3347 HOH M O 1 HETATM 4822 O O . HOH MA 11 . ? 67.375 111.251 39.876 1.00 16.99 ? 3348 HOH M O 1 HETATM 4823 O O . HOH MA 11 . ? 70.183 105.643 43.123 1.00 37.27 ? 3349 HOH M O 1 HETATM 4824 O O . HOH MA 11 . ? 71.948 108.330 45.121 1.00 16.44 ? 3350 HOH M O 1 HETATM 4825 O O . HOH MA 11 . ? 66.132 103.587 42.232 1.00 19.61 ? 3351 HOH M O 1 HETATM 4826 O O . HOH MA 11 . ? 63.053 100.836 39.023 1.00 29.14 ? 3352 HOH M O 1 HETATM 4827 O O . HOH MA 11 . ? 57.303 101.870 33.683 1.00 32.43 ? 3353 HOH M O 1 HETATM 4828 O O . HOH MA 11 . ? 59.359 104.440 33.702 1.00 19.62 ? 3354 HOH M O 1 HETATM 4829 O O . HOH MA 11 . ? 60.133 99.772 40.758 1.00 20.17 ? 3355 HOH M O 1 HETATM 4830 O O . HOH MA 11 . ? 61.199 100.436 43.324 1.00 23.73 ? 3356 HOH M O 1 HETATM 4831 O O . HOH MA 11 . ? 60.254 106.951 42.916 1.00 10.32 ? 3357 HOH M O 1 HETATM 4832 O O . HOH MA 11 . ? 63.447 102.283 41.800 1.00 23.58 ? 3358 HOH M O 1 HETATM 4833 O O . HOH MA 11 . ? 48.504 101.261 44.338 1.00 8.79 ? 3359 HOH M O 1 HETATM 4834 O O . HOH MA 11 . ? 48.446 107.101 39.882 1.00 18.65 ? 3360 HOH M O 1 HETATM 4835 O O . HOH MA 11 . ? 52.405 94.235 50.349 1.00 41.00 ? 3361 HOH M O 1 HETATM 4836 O O . HOH MA 11 . ? 57.118 95.932 47.869 1.00 42.92 ? 3362 HOH M O 1 HETATM 4837 O O . HOH MA 11 . ? 54.578 94.518 48.800 1.00 32.28 ? 3363 HOH M O 1 HETATM 4838 O O . HOH MA 11 . ? 53.392 107.293 53.341 1.00 13.65 ? 3364 HOH M O 1 HETATM 4839 O O . HOH MA 11 . ? 40.911 96.876 58.971 1.00 13.42 ? 3365 HOH M O 1 HETATM 4840 O O . HOH MA 11 . ? 45.924 94.337 62.966 1.00 18.32 ? 3366 HOH M O 1 HETATM 4841 O O . HOH MA 11 . ? 49.751 90.253 62.505 1.00 60.19 ? 3367 HOH M O 1 HETATM 4842 O O . HOH MA 11 . ? 50.880 92.489 57.437 1.00 49.79 ? 3368 HOH M O 1 HETATM 4843 O O . HOH MA 11 . ? 43.650 90.801 63.556 1.00 49.81 ? 3369 HOH M O 1 HETATM 4844 O O . HOH MA 11 . ? 38.941 94.202 61.814 1.00 27.66 ? 3370 HOH M O 1 HETATM 4845 O O . HOH MA 11 . ? 37.335 100.388 68.299 1.00 25.18 ? 3371 HOH M O 1 HETATM 4846 O O . HOH MA 11 . ? 40.746 105.682 71.389 1.00 10.35 ? 3372 HOH M O 1 HETATM 4847 O O . HOH MA 11 . ? 38.909 96.685 60.978 1.00 12.27 ? 3373 HOH M O 1 HETATM 4848 O O . HOH MA 11 . ? 35.245 96.664 67.321 1.00 19.36 ? 3374 HOH M O 1 HETATM 4849 O O . HOH MA 11 . ? 41.570 88.999 64.833 1.00 28.72 ? 3375 HOH M O 1 HETATM 4850 O O . HOH MA 11 . ? 40.314 91.419 71.201 1.00 31.90 ? 3376 HOH M O 1 HETATM 4851 O O . HOH MA 11 . ? 38.851 95.613 71.857 1.00 20.88 ? 3377 HOH M O 1 HETATM 4852 O O . HOH MA 11 . ? 42.547 90.746 68.940 1.00 38.43 ? 3378 HOH M O 1 HETATM 4853 O O . HOH MA 11 . ? 40.283 95.019 74.675 1.00 47.00 ? 3379 HOH M O 1 HETATM 4854 O O . HOH MA 11 . ? 43.177 94.455 74.044 1.00 44.98 ? 3380 HOH M O 1 HETATM 4855 O O . HOH MA 11 . ? 44.230 96.438 74.505 1.00 43.41 ? 3381 HOH M O 1 HETATM 4856 O O . HOH MA 11 . ? 47.908 98.089 75.145 1.00 42.10 ? 3382 HOH M O 1 HETATM 4857 O O . HOH MA 11 . ? 37.347 102.203 70.405 1.00 15.71 ? 3383 HOH M O 1 HETATM 4858 O O . HOH MA 11 . ? 34.826 98.862 68.441 1.00 34.50 ? 3384 HOH M O 1 HETATM 4859 O O . HOH MA 11 . ? 33.882 100.458 70.626 1.00 32.42 ? 3385 HOH M O 1 HETATM 4860 O O . HOH MA 11 . ? 38.938 96.066 74.046 1.00 33.69 ? 3386 HOH M O 1 HETATM 4861 O O . HOH MA 11 . ? 34.871 101.018 78.341 1.00 37.68 ? 3387 HOH M O 1 HETATM 4862 O O . HOH MA 11 . ? 44.279 100.206 76.760 1.00 42.26 ? 3388 HOH M O 1 HETATM 4863 O O . HOH MA 11 . ? 31.357 103.858 71.474 1.00 41.75 ? 3389 HOH M O 1 HETATM 4864 O O . HOH MA 11 . ? 32.955 107.451 73.301 1.00 21.85 ? 3390 HOH M O 1 HETATM 4865 O O . HOH MA 11 . ? 32.678 106.728 69.447 1.00 27.84 ? 3391 HOH M O 1 HETATM 4866 O O . HOH MA 11 . ? 33.467 103.055 69.204 1.00 22.39 ? 3392 HOH M O 1 HETATM 4867 O O . HOH MA 11 . ? 31.796 103.915 67.288 1.00 50.62 ? 3393 HOH M O 1 HETATM 4868 O O . HOH MA 11 . ? 27.968 106.865 66.305 1.00 55.97 ? 3394 HOH M O 1 HETATM 4869 O O . HOH MA 11 . ? 42.745 111.346 46.890 1.00 13.41 ? 3395 HOH M O 1 HETATM 4870 O O . HOH MA 11 . ? 41.510 119.981 46.986 1.00 8.43 ? 3396 HOH M O 1 HETATM 4871 O O . HOH MA 11 . ? 29.546 117.960 38.550 1.00 23.83 ? 3397 HOH M O 1 HETATM 4872 O O . HOH MA 11 . ? 31.998 116.288 37.075 1.00 12.73 ? 3398 HOH M O 1 HETATM 4873 O O . HOH MA 11 . ? 33.411 123.319 31.373 1.00 11.09 ? 3399 HOH M O 1 HETATM 4874 O O . HOH MA 11 . ? 41.051 124.486 23.867 1.00 32.07 ? 3400 HOH M O 1 HETATM 4875 O O . HOH MA 11 . ? 37.540 121.186 23.678 1.00 22.16 ? 3401 HOH M O 1 HETATM 4876 O O . HOH MA 11 . ? 27.178 117.152 27.207 1.00 28.53 ? 3402 HOH M O 1 HETATM 4877 O O . HOH MA 11 . ? 28.264 124.649 30.277 1.00 35.27 ? 3403 HOH M O 1 HETATM 4878 O O . HOH MA 11 . ? 29.020 117.360 30.669 1.00 24.17 ? 3404 HOH M O 1 HETATM 4879 O O . HOH MA 11 . ? 29.466 124.078 26.899 1.00 29.75 ? 3405 HOH M O 1 HETATM 4880 O O . HOH MA 11 . ? 30.195 123.190 24.568 1.00 35.04 ? 3406 HOH M O 1 HETATM 4881 O O . HOH MA 11 . ? 29.888 116.631 20.812 1.00 29.13 ? 3407 HOH M O 1 HETATM 4882 O O . HOH MA 11 . ? 29.608 119.194 21.213 1.00 33.56 ? 3408 HOH M O 1 HETATM 4883 O O . HOH MA 11 . ? 34.366 115.558 20.671 1.00 43.05 ? 3409 HOH M O 1 HETATM 4884 O O . HOH MA 11 . ? 39.038 116.292 23.028 1.00 32.77 ? 3410 HOH M O 1 HETATM 4885 O O . HOH MA 11 . ? 38.031 107.910 19.590 1.00 45.60 ? 3411 HOH M O 1 HETATM 4886 O O . HOH MA 11 . ? 31.934 114.862 21.782 1.00 20.20 ? 3412 HOH M O 1 HETATM 4887 O O . HOH MA 11 . ? 35.108 106.982 18.231 1.00 46.16 ? 3413 HOH M O 1 HETATM 4888 O O . HOH MA 11 . ? 38.410 119.012 25.369 1.00 20.54 ? 3414 HOH M O 1 HETATM 4889 O O . HOH MA 11 . ? 35.940 107.447 31.717 1.00 24.68 ? 3415 HOH M O 1 HETATM 4890 O O . HOH MA 11 . ? 30.265 110.183 38.196 1.00 21.87 ? 3416 HOH M O 1 HETATM 4891 O O . HOH MA 11 . ? 34.038 108.117 37.265 1.00 22.47 ? 3417 HOH M O 1 HETATM 4892 O O . HOH MA 11 . ? 32.209 113.951 33.707 1.00 30.70 ? 3418 HOH M O 1 HETATM 4893 O O . HOH MA 11 . ? 37.965 106.432 29.826 1.00 22.11 ? 3419 HOH M O 1 HETATM 4894 O O . HOH MA 11 . ? 43.398 107.748 28.625 1.00 39.40 ? 3420 HOH M O 1 HETATM 4895 O O . HOH MA 11 . ? 29.794 112.669 39.221 1.00 15.82 ? 3421 HOH M O 1 HETATM 4896 O O . HOH MA 11 . ? 34.853 101.907 40.667 1.00 16.76 ? 3422 HOH M O 1 HETATM 4897 O O . HOH MA 11 . ? 46.245 108.909 39.934 1.00 18.07 ? 3423 HOH M O 1 HETATM 4898 O O . HOH MA 11 . ? 31.253 96.875 48.341 1.00 35.34 ? 3424 HOH M O 1 HETATM 4899 O O . HOH MA 11 . ? 32.683 98.406 52.588 1.00 31.62 ? 3425 HOH M O 1 HETATM 4900 O O . HOH MA 11 . ? 33.371 100.889 45.501 1.00 16.37 ? 3426 HOH M O 1 HETATM 4901 O O . HOH MA 11 . ? 36.911 92.427 47.260 1.00 37.26 ? 3427 HOH M O 1 HETATM 4902 O O . HOH MA 11 . ? 33.661 93.443 47.582 1.00 36.88 ? 3428 HOH M O 1 HETATM 4903 O O . HOH MA 11 . ? 41.392 92.739 45.571 1.00 43.73 ? 3429 HOH M O 1 HETATM 4904 O O . HOH MA 11 . ? 37.827 96.430 40.883 1.00 18.34 ? 3430 HOH M O 1 HETATM 4905 O O . HOH MA 11 . ? 42.412 95.289 42.826 1.00 13.59 ? 3431 HOH M O 1 HETATM 4906 O O . HOH MA 11 . ? 40.500 92.656 35.136 1.00 27.52 ? 3432 HOH M O 1 HETATM 4907 O O . HOH MA 11 . ? 45.252 94.893 33.108 1.00 44.35 ? 3433 HOH M O 1 HETATM 4908 O O . HOH MA 11 . ? 46.144 95.844 31.551 1.00 41.40 ? 3434 HOH M O 1 HETATM 4909 O O . HOH MA 11 . ? 37.676 96.458 31.251 1.00 43.19 ? 3435 HOH M O 1 HETATM 4910 O O . HOH MA 11 . ? 37.435 100.234 33.054 1.00 27.14 ? 3436 HOH M O 1 HETATM 4911 O O . HOH MA 11 . ? 42.142 94.305 32.701 1.00 38.26 ? 3437 HOH M O 1 HETATM 4912 O O . HOH MA 11 . ? 40.043 100.456 29.676 1.00 46.64 ? 3438 HOH M O 1 HETATM 4913 O O . HOH MA 11 . ? 43.026 101.528 30.084 1.00 36.11 ? 3439 HOH M O 1 HETATM 4914 O O . HOH MA 11 . ? 43.411 105.651 32.043 1.00 30.78 ? 3440 HOH M O 1 HETATM 4915 O O . HOH MA 11 . ? 47.870 101.432 29.568 1.00 37.13 ? 3441 HOH M O 1 HETATM 4916 O O . HOH MA 11 . ? 46.301 95.559 36.920 1.00 16.61 ? 3442 HOH M O 1 HETATM 4917 O O . HOH MA 11 . ? 52.781 95.410 40.764 1.00 30.89 ? 3443 HOH M O 1 HETATM 4918 O O . HOH MA 11 . ? 49.183 92.198 36.915 1.00 42.89 ? 3444 HOH M O 1 HETATM 4919 O O . HOH MA 11 . ? 50.941 95.478 32.144 1.00 34.58 ? 3445 HOH M O 1 HETATM 4920 O O . HOH MA 11 . ? 50.748 100.268 31.940 1.00 27.14 ? 3446 HOH M O 1 HETATM 4921 O O . HOH MA 11 . ? 54.396 99.400 40.563 1.00 14.91 ? 3447 HOH M O 1 HETATM 4922 O O . HOH MA 11 . ? 53.711 99.014 32.724 1.00 49.23 ? 3448 HOH M O 1 HETATM 4923 O O . HOH MA 11 . ? 47.763 93.250 39.928 1.00 42.97 ? 3449 HOH M O 1 HETATM 4924 O O . HOH MA 11 . ? 45.042 94.972 41.829 1.00 20.89 ? 3450 HOH M O 1 HETATM 4925 O O . HOH MA 11 . ? 51.328 92.102 43.090 1.00 40.49 ? 3451 HOH M O 1 HETATM 4926 O O . HOH MA 11 . ? 50.936 92.510 46.237 1.00 37.27 ? 3452 HOH M O 1 HETATM 4927 O O . HOH MA 11 . ? 49.196 90.349 47.130 1.00 34.73 ? 3453 HOH M O 1 HETATM 4928 O O . HOH MA 11 . ? 43.749 92.801 43.841 1.00 34.25 ? 3454 HOH M O 1 HETATM 4929 O O . HOH MA 11 . ? 41.627 89.653 46.356 1.00 51.86 ? 3455 HOH M O 1 HETATM 4930 O O . HOH MA 11 . ? 47.990 88.227 45.964 1.00 47.74 ? 3456 HOH M O 1 HETATM 4931 O O . HOH MA 11 . ? 47.871 87.769 52.343 1.00 36.11 ? 3457 HOH M O 1 HETATM 4932 O O . HOH MA 11 . ? 38.592 88.905 50.036 1.00 25.90 ? 3458 HOH M O 1 HETATM 4933 O O . HOH MA 11 . ? 44.801 85.551 51.417 1.00 28.30 ? 3459 HOH M O 1 HETATM 4934 O O . HOH MA 11 . ? 45.022 90.251 57.544 1.00 43.27 ? 3460 HOH M O 1 HETATM 4935 O O . HOH MA 11 . ? 41.600 89.492 56.282 1.00 24.84 ? 3461 HOH M O 1 HETATM 4936 O O . HOH MA 11 . ? 50.329 89.441 49.304 1.00 50.40 ? 3462 HOH M O 1 HETATM 4937 O O . HOH MA 11 . ? 50.076 93.011 48.753 1.00 23.17 ? 3463 HOH M O 1 HETATM 4938 O O . HOH MA 11 . ? 50.250 91.933 53.473 1.00 39.75 ? 3464 HOH M O 1 HETATM 4939 O O . HOH MA 11 . ? 38.935 90.998 46.081 1.00 42.57 ? 3465 HOH M O 1 HETATM 4940 O O . HOH MA 11 . ? 37.124 91.153 50.400 1.00 30.30 ? 3466 HOH M O 1 HETATM 4941 O O . HOH MA 11 . ? 36.032 93.544 55.226 1.00 19.75 ? 3467 HOH M O 1 HETATM 4942 O O . HOH MA 11 . ? 29.915 94.700 50.256 1.00 44.75 ? 3468 HOH M O 1 HETATM 4943 O O . HOH MA 11 . ? 37.527 96.294 57.616 1.00 17.80 ? 3469 HOH M O 1 HETATM 4944 O O . HOH MA 11 . ? 32.603 100.400 53.880 1.00 36.11 ? 3470 HOH M O 1 HETATM 4945 O O . HOH MA 11 . ? 33.046 101.153 56.938 1.00 26.26 ? 3471 HOH M O 1 HETATM 4946 O O . HOH MA 11 . ? 30.841 104.338 53.729 1.00 17.53 ? 3472 HOH M O 1 HETATM 4947 O O . HOH MA 11 . ? 36.015 102.003 66.307 1.00 16.68 ? 3473 HOH M O 1 HETATM 4948 O O . HOH MA 11 . ? 33.751 100.557 65.162 1.00 27.06 ? 3474 HOH M O 1 HETATM 4949 O O . HOH MA 11 . ? 32.083 101.669 62.022 1.00 32.36 ? 3475 HOH M O 1 HETATM 4950 O O . HOH MA 11 . ? 30.972 105.148 62.463 1.00 24.62 ? 3476 HOH M O 1 HETATM 4951 O O . HOH MA 11 . ? 31.177 105.684 58.059 1.00 14.54 ? 3477 HOH M O 1 HETATM 4952 O O . HOH MA 11 . ? 29.073 121.665 11.620 1.00 43.74 ? 3478 HOH M O 1 HETATM 4953 O O . HOH MA 11 . ? 32.194 124.714 12.817 1.00 45.19 ? 3479 HOH M O 1 HETATM 4954 O O . HOH MA 11 . ? 43.019 92.574 39.368 1.00 31.26 ? 3480 HOH M O 1 HETATM 4955 O O . HOH MA 11 . ? 41.017 82.972 33.623 1.00 33.69 ? 3481 HOH M O 1 HETATM 4956 O O . HOH MA 11 . ? 38.816 125.176 41.942 1.00 8.32 ? 3482 HOH M O 1 HETATM 4957 O O . HOH MA 11 . ? 44.288 80.735 31.129 1.00 46.28 ? 3483 HOH M O 1 HETATM 4958 O O . HOH MA 11 . ? 73.319 118.914 46.238 1.00 18.50 ? 3484 HOH M O 1 HETATM 4959 O O . HOH MA 11 . ? 32.237 125.569 34.918 1.00 21.92 ? 3485 HOH M O 1 HETATM 4960 O O . HOH MA 11 . ? 44.161 122.425 25.603 1.00 53.38 ? 3486 HOH M O 1 HETATM 4961 O O . HOH MA 11 . ? 44.080 123.821 28.121 1.00 18.10 ? 3487 HOH M O 1 HETATM 4962 O O . HOH MA 11 . ? 43.156 117.790 25.548 1.00 21.29 ? 3488 HOH M O 1 HETATM 4963 O O . HOH MA 11 . ? 46.420 117.281 26.635 1.00 34.21 ? 3489 HOH M O 1 HETATM 4964 O O . HOH MA 11 . ? 45.126 113.475 24.300 1.00 38.42 ? 3490 HOH M O 1 HETATM 4965 O O . HOH MA 11 . ? 45.701 108.518 27.600 1.00 35.13 ? 3491 HOH M O 1 HETATM 4966 O O . HOH MA 11 . ? 48.850 116.946 27.966 1.00 33.52 ? 3492 HOH M O 1 HETATM 4967 O O . HOH MA 11 . ? 51.209 113.119 28.590 1.00 36.24 ? 3493 HOH M O 1 HETATM 4968 O O . HOH MA 11 . ? 48.470 111.813 30.853 1.00 16.62 ? 3494 HOH M O 1 HETATM 4969 O O . HOH MA 11 . ? 49.680 115.930 23.824 1.00 49.98 ? 3495 HOH M O 1 HETATM 4970 O O . HOH MA 11 . ? 49.075 104.707 26.879 1.00 26.95 ? 3496 HOH M O 1 HETATM 4971 O O . HOH MA 11 . ? 47.998 107.487 25.088 1.00 35.01 ? 3497 HOH M O 1 HETATM 4972 O O . HOH MA 11 . ? 47.140 104.345 29.036 1.00 31.10 ? 3498 HOH M O 1 HETATM 4973 O O . HOH MA 11 . ? 52.058 108.589 24.504 1.00 54.26 ? 3499 HOH M O 1 HETATM 4974 O O . HOH MA 11 . ? 53.166 102.747 24.275 1.00 49.41 ? 3500 HOH M O 1 HETATM 4975 O O . HOH MA 11 . ? 55.691 103.879 23.255 1.00 71.86 ? 3501 HOH M O 1 HETATM 4976 O O . HOH MA 11 . ? 55.140 105.428 25.441 1.00 35.44 ? 3502 HOH M O 1 HETATM 4977 O O . HOH MA 11 . ? 58.977 104.382 31.174 1.00 27.69 ? 3503 HOH M O 1 HETATM 4978 O O . HOH MA 11 . ? 61.045 110.950 28.392 1.00 40.31 ? 3504 HOH M O 1 HETATM 4979 O O . HOH MA 11 . ? 61.911 108.640 26.606 1.00 34.78 ? 3505 HOH M O 1 HETATM 4980 O O . HOH MA 11 . ? 64.098 108.258 33.982 1.00 16.26 ? 3506 HOH M O 1 HETATM 4981 O O . HOH MA 11 . ? 57.548 113.583 33.459 1.00 26.81 ? 3507 HOH M O 1 HETATM 4982 O O . HOH MA 11 . ? 59.971 114.995 33.140 1.00 46.25 ? 3508 HOH M O 1 HETATM 4983 O O . HOH MA 11 . ? 59.688 107.129 34.609 1.00 14.47 ? 3509 HOH M O 1 HETATM 4984 O O . HOH MA 11 . ? 53.535 113.811 35.908 1.00 22.30 ? 3510 HOH M O 1 HETATM 4985 O O . HOH MA 11 . ? 47.170 108.860 37.231 1.00 30.77 ? 3511 HOH M O 1 HETATM 4986 O O . HOH MA 11 . ? 46.817 112.575 37.244 1.00 20.96 ? 3512 HOH M O 1 HETATM 4987 O O . HOH MA 11 . ? 47.026 112.177 33.703 1.00 17.81 ? 3513 HOH M O 1 HETATM 4988 O O . HOH MA 11 . ? 45.365 106.664 30.214 1.00 35.94 ? 3514 HOH M O 1 HETATM 4989 O O . HOH MA 11 . ? 49.009 113.944 32.111 1.00 34.94 ? 3515 HOH M O 1 HETATM 4990 O O . HOH MA 11 . ? 47.709 118.376 34.504 1.00 17.63 ? 3516 HOH M O 1 HETATM 4991 O O . HOH MA 11 . ? 47.779 121.805 33.021 1.00 26.91 ? 3517 HOH M O 1 HETATM 4992 O O . HOH MA 11 . ? 46.424 122.332 37.316 1.00 26.31 ? 3518 HOH M O 1 HETATM 4993 O O . HOH MA 11 . ? 41.774 120.768 31.543 1.00 10.15 ? 3519 HOH M O 1 HETATM 4994 O O . HOH MA 11 . ? 47.423 122.772 40.502 1.00 28.99 ? 3520 HOH M O 1 HETATM 4995 O O . HOH MA 11 . ? 44.914 126.508 34.616 1.00 12.92 ? 3521 HOH M O 1 HETATM 4996 O O . HOH MA 11 . ? 40.878 127.811 27.441 1.00 26.78 ? 3522 HOH M O 1 HETATM 4997 O O . HOH MA 11 . ? 32.251 130.334 29.017 1.00 29.32 ? 3523 HOH M O 1 HETATM 4998 O O . HOH MA 11 . ? 35.531 133.400 28.480 1.00 22.70 ? 3524 HOH M O 1 HETATM 4999 O O . HOH MA 11 . ? 34.269 132.112 25.155 1.00 23.48 ? 3525 HOH M O 1 HETATM 5000 O O . HOH MA 11 . ? 39.711 134.191 30.852 1.00 17.54 ? 3526 HOH M O 1 HETATM 5001 O O . HOH MA 11 . ? 36.595 133.884 33.761 1.00 18.27 ? 3527 HOH M O 1 HETATM 5002 O O . HOH MA 11 . ? 43.470 136.670 34.955 1.00 42.83 ? 3528 HOH M O 1 HETATM 5003 O O . HOH MA 11 . ? 46.312 131.560 32.131 1.00 62.99 ? 3529 HOH M O 1 HETATM 5004 O O . HOH MA 11 . ? 44.086 133.324 30.789 1.00 44.04 ? 3530 HOH M O 1 HETATM 5005 O O . HOH MA 11 . ? 35.896 133.339 37.143 1.00 17.21 ? 3531 HOH M O 1 HETATM 5006 O O . HOH MA 11 . ? 32.729 128.181 37.756 1.00 15.29 ? 3532 HOH M O 1 HETATM 5007 O O . HOH MA 11 . ? 38.194 134.267 38.592 1.00 12.84 ? 3533 HOH M O 1 HETATM 5008 O O . HOH MA 11 . ? 40.993 135.173 46.638 1.00 16.66 ? 3534 HOH M O 1 HETATM 5009 O O . HOH MA 11 . ? 40.007 136.407 42.109 1.00 12.21 ? 3535 HOH M O 1 HETATM 5010 O O . HOH MA 11 . ? 45.421 133.298 48.022 1.00 27.12 ? 3536 HOH M O 1 HETATM 5011 O O . HOH MA 11 . ? 50.874 125.471 44.867 1.00 45.11 ? 3537 HOH M O 1 HETATM 5012 O O . HOH MA 11 . ? 50.432 125.636 49.450 1.00 39.71 ? 3538 HOH M O 1 HETATM 5013 O O . HOH MA 11 . ? 47.893 137.430 37.485 1.00 53.25 ? 3539 HOH M O 1 HETATM 5014 O O . HOH MA 11 . ? 52.808 128.683 43.956 1.00 36.25 ? 3540 HOH M O 1 HETATM 5015 O O . HOH MA 11 . ? 51.441 132.222 46.816 1.00 35.83 ? 3541 HOH M O 1 HETATM 5016 O O . HOH MA 11 . ? 47.837 133.859 46.595 1.00 27.04 ? 3542 HOH M O 1 HETATM 5017 O O . HOH MA 11 . ? 54.766 133.216 43.526 1.00 58.92 ? 3543 HOH M O 1 HETATM 5018 O O . HOH MA 11 . ? 53.691 132.803 31.899 1.00 31.91 ? 3544 HOH M O 1 HETATM 5019 O O . HOH MA 11 . ? 54.200 134.849 35.173 1.00 34.22 ? 3545 HOH M O 1 HETATM 5020 O O . HOH MA 11 . ? 51.213 138.753 35.303 1.00 56.48 ? 3546 HOH M O 1 HETATM 5021 O O . HOH MA 11 . ? 46.050 131.987 35.492 1.00 27.77 ? 3547 HOH M O 1 HETATM 5022 O O . HOH MA 11 . ? 45.938 129.415 32.453 1.00 33.16 ? 3548 HOH M O 1 HETATM 5023 O O . HOH MA 11 . ? 48.339 125.230 37.861 1.00 30.79 ? 3549 HOH M O 1 HETATM 5024 O O . HOH MA 11 . ? 50.412 126.858 40.636 1.00 35.18 ? 3550 HOH M O 1 HETATM 5025 O O . HOH MA 11 . ? 45.506 128.674 36.017 1.00 17.55 ? 3551 HOH M O 1 HETATM 5026 O O . HOH MA 11 . ? 43.822 136.200 38.615 1.00 42.21 ? 3552 HOH M O 1 HETATM 5027 O O . HOH MA 11 . ? 38.919 134.763 48.456 1.00 11.42 ? 3553 HOH M O 1 HETATM 5028 O O . HOH MA 11 . ? 30.461 124.221 37.189 1.00 31.41 ? 3554 HOH M O 1 HETATM 5029 O O . HOH MA 11 . ? 30.086 120.970 40.556 1.00 12.49 ? 3555 HOH M O 1 HETATM 5030 O O . HOH MA 11 . ? 24.200 125.217 43.227 1.00 41.89 ? 3556 HOH M O 1 HETATM 5031 O O . HOH MA 11 . ? 27.840 117.568 41.728 1.00 30.39 ? 3557 HOH M O 1 HETATM 5032 O O . HOH MA 11 . ? 24.650 117.028 43.315 1.00 64.44 ? 3558 HOH M O 1 HETATM 5033 O O . HOH MA 11 . ? 22.669 113.412 44.522 1.00 23.83 ? 3559 HOH M O 1 HETATM 5034 O O . HOH MA 11 . ? 28.328 115.212 43.142 1.00 13.63 ? 3560 HOH M O 1 HETATM 5035 O O . HOH MA 11 . ? 24.063 112.576 47.876 1.00 28.63 ? 3561 HOH M O 1 HETATM 5036 O O . HOH MA 11 . ? 24.388 114.222 42.148 1.00 43.73 ? 3562 HOH M O 1 HETATM 5037 O O . HOH MA 11 . ? 35.706 107.646 42.058 1.00 18.16 ? 3563 HOH M O 1 HETATM 5038 O O . HOH MA 11 . ? 22.651 106.919 50.814 1.00 36.70 ? 3564 HOH M O 1 HETATM 5039 O O . HOH MA 11 . ? 19.624 109.345 51.589 1.00 45.24 ? 3565 HOH M O 1 HETATM 5040 O O . HOH MA 11 . ? 24.475 105.974 49.081 1.00 26.73 ? 3566 HOH M O 1 HETATM 5041 O O . HOH MA 11 . ? 26.938 106.682 42.450 1.00 32.15 ? 3567 HOH M O 1 HETATM 5042 O O . HOH MA 11 . ? 22.809 108.575 47.835 1.00 36.87 ? 3568 HOH M O 1 HETATM 5043 O O . HOH MA 11 . ? 27.143 103.987 47.424 1.00 16.83 ? 3569 HOH M O 1 HETATM 5044 O O . HOH MA 11 . ? 23.886 105.530 45.591 1.00 37.11 ? 3570 HOH M O 1 HETATM 5045 O O . HOH MA 11 . ? 27.312 104.051 43.037 1.00 36.35 ? 3571 HOH M O 1 HETATM 5046 O O . HOH MA 11 . ? 27.077 110.959 42.409 1.00 24.93 ? 3572 HOH M O 1 HETATM 5047 O O . HOH MA 11 . ? 31.313 102.470 44.484 1.00 22.04 ? 3573 HOH M O 1 HETATM 5048 O O . HOH MA 11 . ? 28.180 102.421 45.184 1.00 32.21 ? 3574 HOH M O 1 HETATM 5049 O O . HOH MA 11 . ? 30.456 102.060 42.109 1.00 33.36 ? 3575 HOH M O 1 HETATM 5050 O O . HOH MA 11 . ? 28.648 103.466 41.144 1.00 53.54 ? 3576 HOH M O 1 HETATM 5051 O O . HOH MA 11 . ? 32.375 102.072 39.936 1.00 27.84 ? 3577 HOH M O 1 HETATM 5052 O O . HOH MA 11 . ? 36.206 103.971 43.051 1.00 16.80 ? 3578 HOH M O 1 HETATM 5053 O O . HOH MA 11 . ? 29.270 102.917 55.328 1.00 30.51 ? 3579 HOH M O 1 HETATM 5054 O O . HOH MA 11 . ? 31.787 98.756 45.579 1.00 23.39 ? 3580 HOH M O 1 HETATM 5055 O O . HOH MA 11 . ? 23.373 103.949 54.822 1.00 38.65 ? 3581 HOH M O 1 HETATM 5056 O O . HOH MA 11 . ? 26.684 104.152 55.947 1.00 25.77 ? 3582 HOH M O 1 HETATM 5057 O O . HOH MA 11 . ? 23.972 107.246 58.288 1.00 32.32 ? 3583 HOH M O 1 HETATM 5058 O O . HOH MA 11 . ? 26.731 107.381 57.720 1.00 15.55 ? 3584 HOH M O 1 HETATM 5059 O O . HOH MA 11 . ? 27.159 110.537 54.030 1.00 11.32 ? 3585 HOH M O 1 HETATM 5060 O O . HOH MA 11 . ? 30.701 110.683 65.322 1.00 24.63 ? 3586 HOH M O 1 HETATM 5061 O O . HOH MA 11 . ? 30.854 114.059 66.281 1.00 31.73 ? 3587 HOH M O 1 HETATM 5062 O O . HOH MA 11 . ? 47.400 117.950 54.522 1.00 17.44 ? 3588 HOH M O 1 HETATM 5063 O O . HOH MA 11 . ? 49.263 132.891 48.794 1.00 20.34 ? 3589 HOH M O 1 HETATM 5064 O O . HOH MA 11 . ? 46.209 129.205 48.876 1.00 19.55 ? 3590 HOH M O 1 HETATM 5065 O O . HOH MA 11 . ? 49.934 137.023 54.240 1.00 22.99 ? 3591 HOH M O 1 HETATM 5066 O O . HOH MA 11 . ? 47.063 136.051 56.345 1.00 15.62 ? 3592 HOH M O 1 HETATM 5067 O O . HOH MA 11 . ? 55.916 137.011 55.893 1.00 35.26 ? 3593 HOH M O 1 HETATM 5068 O O . HOH MA 11 . ? 57.894 135.258 52.570 1.00 34.87 ? 3594 HOH M O 1 HETATM 5069 O O . HOH MA 11 . ? 55.108 135.744 48.985 1.00 36.46 ? 3595 HOH M O 1 HETATM 5070 O O . HOH MA 11 . ? 45.895 139.104 53.599 1.00 21.65 ? 3596 HOH M O 1 HETATM 5071 O O . HOH MA 11 . ? 56.848 140.171 54.558 1.00 38.17 ? 3597 HOH M O 1 HETATM 5072 O O . HOH MA 11 . ? 49.073 139.933 48.296 1.00 34.46 ? 3598 HOH M O 1 HETATM 5073 O O . HOH MA 11 . ? 45.992 138.448 49.853 1.00 30.41 ? 3599 HOH M O 1 HETATM 5074 O O . HOH MA 11 . ? 55.558 143.557 58.794 1.00 31.07 ? 3600 HOH M O 1 HETATM 5075 O O . HOH MA 11 . ? 52.496 140.384 65.421 1.00 38.34 ? 3601 HOH M O 1 HETATM 5076 O O . HOH MA 11 . ? 52.486 146.024 58.964 1.00 29.63 ? 3602 HOH M O 1 HETATM 5077 O O . HOH MA 11 . ? 45.984 145.068 60.116 1.00 40.41 ? 3603 HOH M O 1 HETATM 5078 O O . HOH MA 11 . ? 53.889 143.896 51.150 1.00 36.15 ? 3604 HOH M O 1 HETATM 5079 O O . HOH MA 11 . ? 43.838 142.847 52.735 1.00 41.83 ? 3605 HOH M O 1 HETATM 5080 O O . HOH MA 11 . ? 42.054 140.906 51.344 1.00 25.43 ? 3606 HOH M O 1 HETATM 5081 O O . HOH MA 11 . ? 36.222 145.397 58.204 1.00 38.47 ? 3607 HOH M O 1 HETATM 5082 O O . HOH MA 11 . ? 40.353 147.105 56.051 1.00 19.92 ? 3608 HOH M O 1 HETATM 5083 O O . HOH MA 11 . ? 43.592 135.178 47.941 1.00 33.30 ? 3609 HOH M O 1 HETATM 5084 O O . HOH MA 11 . ? 43.561 138.910 52.080 1.00 20.15 ? 3610 HOH M O 1 HETATM 5085 O O . HOH MA 11 . ? 32.952 139.756 51.765 1.00 45.69 ? 3611 HOH M O 1 HETATM 5086 O O . HOH MA 11 . ? 35.412 139.317 53.707 1.00 28.33 ? 3612 HOH M O 1 HETATM 5087 O O . HOH MA 11 . ? 33.688 139.234 48.737 1.00 19.31 ? 3613 HOH M O 1 HETATM 5088 O O . HOH MA 11 . ? 37.978 137.364 48.510 1.00 16.03 ? 3614 HOH M O 1 HETATM 5089 O O . HOH MA 11 . ? 36.766 140.426 50.202 1.00 22.83 ? 3615 HOH M O 1 HETATM 5090 O O . HOH MA 11 . ? 37.345 125.242 46.240 1.00 9.41 ? 3616 HOH M O 1 HETATM 5091 O O . HOH MA 11 . ? 24.169 127.655 53.898 1.00 27.00 ? 3617 HOH M O 1 HETATM 5092 O O . HOH MA 11 . ? 20.334 126.802 56.624 1.00 34.59 ? 3618 HOH M O 1 HETATM 5093 O O . HOH MA 11 . ? 23.820 121.688 58.057 1.00 24.87 ? 3619 HOH M O 1 HETATM 5094 O O . HOH MA 11 . ? 20.796 126.696 44.285 1.00 54.94 ? 3620 HOH M O 1 HETATM 5095 O O . HOH MA 11 . ? 19.915 116.729 56.287 1.00 39.26 ? 3621 HOH M O 1 HETATM 5096 O O . HOH MA 11 . ? 17.662 116.128 52.362 1.00 44.89 ? 3622 HOH M O 1 HETATM 5097 O O . HOH MA 11 . ? 21.630 120.581 59.008 1.00 35.47 ? 3623 HOH M O 1 HETATM 5098 O O . HOH MA 11 . ? 20.425 121.915 61.123 1.00 45.32 ? 3624 HOH M O 1 HETATM 5099 O O . HOH MA 11 . ? 18.489 114.076 50.656 1.00 48.31 ? 3625 HOH M O 1 HETATM 5100 O O . HOH MA 11 . ? 17.965 124.231 49.633 1.00 31.41 ? 3626 HOH M O 1 HETATM 5101 O O . HOH MA 11 . ? 22.426 118.022 42.415 1.00 55.07 ? 3627 HOH M O 1 HETATM 5102 O O . HOH MA 11 . ? 18.520 116.456 45.836 1.00 45.52 ? 3628 HOH M O 1 HETATM 5103 O O . HOH MA 11 . ? 21.629 112.257 48.733 1.00 23.62 ? 3629 HOH M O 1 HETATM 5104 O O . HOH MA 11 . ? 22.815 111.921 57.991 1.00 49.27 ? 3630 HOH M O 1 HETATM 5105 O O . HOH MA 11 . ? 20.835 108.901 54.739 1.00 46.54 ? 3631 HOH M O 1 HETATM 5106 O O . HOH MA 11 . ? 23.059 114.679 57.383 1.00 24.41 ? 3632 HOH M O 1 HETATM 5107 O O . HOH MA 11 . ? 23.169 110.221 55.455 1.00 22.90 ? 3633 HOH M O 1 HETATM 5108 O O . HOH MA 11 . ? 26.939 108.720 62.190 1.00 22.03 ? 3634 HOH M O 1 HETATM 5109 O O . HOH MA 11 . ? 25.373 117.469 60.505 1.00 18.04 ? 3635 HOH M O 1 HETATM 5110 O O . HOH MA 11 . ? 43.104 129.247 55.823 1.00 9.71 ? 3636 HOH M O 1 HETATM 5111 O O . HOH MA 11 . ? 50.544 127.624 63.854 1.00 22.83 ? 3637 HOH M O 1 HETATM 5112 O O . HOH MA 11 . ? 50.310 125.779 56.317 1.00 15.44 ? 3638 HOH M O 1 HETATM 5113 O O . HOH MA 11 . ? 49.833 123.349 61.029 1.00 33.97 ? 3639 HOH M O 1 HETATM 5114 O O . HOH MA 11 . ? 48.772 125.758 62.845 1.00 16.99 ? 3640 HOH M O 1 HETATM 5115 O O . HOH MA 11 . ? 50.553 120.354 51.781 1.00 40.32 ? 3641 HOH M O 1 HETATM 5116 O O . HOH MA 11 . ? 52.185 121.983 50.380 1.00 31.19 ? 3642 HOH M O 1 HETATM 5117 O O . HOH MA 11 . ? 56.305 124.147 45.494 1.00 49.76 ? 3643 HOH M O 1 HETATM 5118 O O . HOH MA 11 . ? 57.666 122.351 45.212 1.00 50.40 ? 3644 HOH M O 1 HETATM 5119 O O . HOH MA 11 . ? 52.091 122.748 48.156 1.00 52.37 ? 3645 HOH M O 1 HETATM 5120 O O . HOH MA 11 . ? 52.770 129.809 46.673 1.00 37.93 ? 3646 HOH M O 1 HETATM 5121 O O . HOH MA 11 . ? 54.727 133.136 56.670 1.00 37.38 ? 3647 HOH M O 1 HETATM 5122 O O . HOH MA 11 . ? 55.366 130.193 47.385 1.00 31.89 ? 3648 HOH M O 1 HETATM 5123 O O . HOH MA 11 . ? 54.044 133.499 48.154 1.00 30.24 ? 3649 HOH M O 1 HETATM 5124 O O . HOH MA 11 . ? 53.553 130.585 57.178 1.00 19.18 ? 3650 HOH M O 1 HETATM 5125 O O . HOH MA 11 . ? 52.960 137.844 55.700 1.00 36.17 ? 3651 HOH M O 1 HETATM 5126 O O . HOH MA 11 . ? 50.873 128.749 57.080 1.00 16.74 ? 3652 HOH M O 1 HETATM 5127 O O . HOH MA 11 . ? 51.996 137.231 66.396 1.00 41.22 ? 3653 HOH M O 1 HETATM 5128 O O . HOH MA 11 . ? 54.173 139.670 57.856 1.00 38.46 ? 3654 HOH M O 1 HETATM 5129 O O . HOH MA 11 . ? 59.167 141.154 65.673 1.00 42.76 ? 3655 HOH M O 1 HETATM 5130 O O . HOH MA 11 . ? 56.698 140.321 67.597 1.00 47.89 ? 3656 HOH M O 1 HETATM 5131 O O . HOH MA 11 . ? 62.795 134.072 65.576 1.00 35.24 ? 3657 HOH M O 1 HETATM 5132 O O . HOH MA 11 . ? 56.772 137.472 60.365 1.00 23.55 ? 3658 HOH M O 1 HETATM 5133 O O . HOH MA 11 . ? 61.064 131.971 62.750 1.00 20.11 ? 3659 HOH M O 1 HETATM 5134 O O . HOH MA 11 . ? 59.870 133.452 71.022 1.00 45.41 ? 3660 HOH M O 1 HETATM 5135 O O . HOH MA 11 . ? 55.359 137.153 69.857 1.00 23.19 ? 3661 HOH M O 1 HETATM 5136 O O . HOH MA 11 . ? 60.928 133.335 67.958 1.00 25.00 ? 3662 HOH M O 1 HETATM 5137 O O . HOH MA 11 . ? 58.063 134.919 74.682 1.00 44.21 ? 3663 HOH M O 1 HETATM 5138 O O . HOH MA 11 . ? 51.630 138.379 74.474 1.00 44.72 ? 3664 HOH M O 1 HETATM 5139 O O . HOH MA 11 . ? 54.111 135.830 66.972 1.00 18.51 ? 3665 HOH M O 1 HETATM 5140 O O . HOH MA 11 . ? 51.553 140.057 69.244 1.00 39.71 ? 3666 HOH M O 1 HETATM 5141 O O . HOH MA 11 . ? 51.253 134.503 73.415 1.00 52.36 ? 3667 HOH M O 1 HETATM 5142 O O . HOH MA 11 . ? 54.368 139.122 68.687 1.00 41.56 ? 3668 HOH M O 1 HETATM 5143 O O . HOH MA 11 . ? 49.062 134.301 71.710 1.00 23.85 ? 3669 HOH M O 1 HETATM 5144 O O . HOH MA 11 . ? 46.152 139.319 69.294 1.00 65.83 ? 3670 HOH M O 1 HETATM 5145 O O . HOH MA 11 . ? 47.951 136.834 71.220 1.00 39.01 ? 3671 HOH M O 1 HETATM 5146 O O . HOH MA 11 . ? 44.157 137.176 69.442 1.00 41.95 ? 3672 HOH M O 1 HETATM 5147 O O . HOH MA 11 . ? 44.198 139.948 66.896 1.00 30.96 ? 3673 HOH M O 1 HETATM 5148 O O . HOH MA 11 . ? 36.449 139.763 61.044 1.00 16.70 ? 3674 HOH M O 1 HETATM 5149 O O . HOH MA 11 . ? 42.828 140.898 63.578 1.00 36.48 ? 3675 HOH M O 1 HETATM 5150 O O . HOH MA 11 . ? 39.308 143.557 63.937 1.00 33.86 ? 3676 HOH M O 1 HETATM 5151 O O . HOH MA 11 . ? 36.742 141.632 63.027 1.00 40.14 ? 3677 HOH M O 1 HETATM 5152 O O . HOH MA 11 . ? 35.038 138.000 66.906 1.00 25.37 ? 3678 HOH M O 1 HETATM 5153 O O . HOH MA 11 . ? 38.423 138.621 68.709 1.00 43.82 ? 3679 HOH M O 1 HETATM 5154 O O . HOH MA 11 . ? 28.156 138.426 66.435 1.00 41.08 ? 3680 HOH M O 1 HETATM 5155 O O . HOH MA 11 . ? 31.693 135.927 69.432 1.00 39.07 ? 3681 HOH M O 1 HETATM 5156 O O . HOH MA 11 . ? 26.429 132.243 70.620 1.00 28.43 ? 3682 HOH M O 1 HETATM 5157 O O . HOH MA 11 . ? 21.097 129.372 56.395 1.00 44.57 ? 3683 HOH M O 1 HETATM 5158 O O . HOH MA 11 . ? 21.753 131.636 66.389 1.00 39.23 ? 3684 HOH M O 1 HETATM 5159 O O . HOH MA 11 . ? 27.392 133.061 72.839 1.00 41.44 ? 3685 HOH M O 1 HETATM 5160 O O . HOH MA 11 . ? 26.124 129.504 70.033 1.00 41.96 ? 3686 HOH M O 1 HETATM 5161 O O . HOH MA 11 . ? 33.485 133.232 71.624 1.00 28.39 ? 3687 HOH M O 1 HETATM 5162 O O . HOH MA 11 . ? 29.154 127.695 69.838 1.00 31.42 ? 3688 HOH M O 1 HETATM 5163 O O . HOH MA 11 . ? 60.164 101.183 30.357 1.00 41.84 ? 3689 HOH M O 1 HETATM 5164 O O . HOH MA 11 . ? 61.944 98.781 38.876 1.00 40.52 ? 3690 HOH M O 1 HETATM 5165 O O . HOH MA 11 . ? 66.107 104.407 36.261 1.00 47.36 ? 3691 HOH M O 1 HETATM 5166 O O . HOH MA 11 . ? 63.900 99.715 33.218 1.00 43.53 ? 3692 HOH M O 1 HETATM 5167 O O . HOH MA 11 . ? 64.972 100.587 36.023 1.00 52.58 ? 3693 HOH M O 1 HETATM 5168 O O . HOH MA 11 . ? 60.094 94.406 34.536 1.00 48.15 ? 3694 HOH M O 1 HETATM 5169 O O . HOH MA 11 . ? 36.957 119.617 21.327 1.00 34.73 ? 3695 HOH M O 1 HETATM 5170 O O . HOH MA 11 . ? 31.480 124.872 23.098 1.00 25.81 ? 3696 HOH M O 1 HETATM 5171 O O . HOH MA 11 . ? 39.249 122.893 22.805 1.00 41.17 ? 3697 HOH M O 1 HETATM 5172 O O . HOH MA 11 . ? 38.156 126.600 22.505 1.00 45.72 ? 3698 HOH M O 1 HETATM 5173 O O . HOH MA 11 . ? 29.406 119.060 14.137 1.00 39.06 ? 3699 HOH M O 1 HETATM 5174 O O . HOH MA 11 . ? 32.425 116.992 17.251 1.00 29.16 ? 3700 HOH M O 1 HETATM 5175 O O . HOH MA 11 . ? 37.262 123.058 19.353 1.00 35.49 ? 3701 HOH M O 1 HETATM 5176 O O . HOH MA 11 . ? 31.050 122.666 13.514 1.00 38.05 ? 3702 HOH M O 1 HETATM 5177 O O . HOH MA 11 . ? 29.834 122.012 20.063 1.00 45.22 ? 3703 HOH M O 1 HETATM 5178 O O . HOH MA 11 . ? 32.499 119.410 7.093 1.00 54.26 ? 3704 HOH M O 1 HETATM 5179 O O . HOH MA 11 . ? 32.575 114.813 12.507 1.00 30.15 ? 3705 HOH M O 1 HETATM 5180 O O . HOH MA 11 . ? 32.613 118.328 12.145 1.00 39.04 ? 3706 HOH M O 1 HETATM 5181 O O . HOH MA 11 . ? 37.035 99.312 43.257 1.00 15.63 ? 3707 HOH M O 1 HETATM 5182 O O . HOH MA 11 . ? 31.420 98.116 39.742 1.00 76.64 ? 3708 HOH M O 1 HETATM 5183 O O . HOH MA 11 . ? 35.844 94.027 33.983 1.00 35.80 ? 3709 HOH M O 1 HETATM 5184 O O . HOH MA 11 . ? 33.989 98.012 35.239 1.00 18.36 ? 3710 HOH M O 1 HETATM 5185 O O . HOH MA 11 . ? 36.806 87.678 42.456 1.00 39.65 ? 3711 HOH M O 1 HETATM 5186 O O . HOH MA 11 . ? 40.978 92.029 37.741 1.00 30.01 ? 3712 HOH M O 1 HETATM 5187 O O . HOH MA 11 . ? 29.531 88.419 41.689 1.00 57.66 ? 3713 HOH M O 1 HETATM 5188 O O . HOH MA 11 . ? 38.394 93.730 40.649 1.00 21.10 ? 3714 HOH M O 1 HETATM 5189 O O . HOH MA 11 . ? 33.655 84.753 38.928 1.00 50.56 ? 3715 HOH M O 1 HETATM 5190 O O . HOH MA 11 . ? 38.724 83.242 32.500 1.00 26.09 ? 3716 HOH M O 1 HETATM 5191 O O . HOH MA 11 . ? 41.625 84.976 35.125 1.00 31.55 ? 3717 HOH M O 1 HETATM 5192 O O . HOH MA 11 . ? 36.575 87.068 31.037 1.00 30.00 ? 3718 HOH M O 1 HETATM 5193 O O . HOH MA 11 . ? 39.959 89.559 40.456 1.00 46.63 ? 3719 HOH M O 1 HETATM 5194 O O . HOH MA 11 . ? 38.394 85.773 38.325 1.00 32.16 ? 3720 HOH M O 1 HETATM 5195 O O . HOH MA 11 . ? 42.821 82.642 31.803 1.00 49.91 ? 3721 HOH M O 1 HETATM 5196 O O . HOH MA 11 . ? 38.308 86.187 29.166 1.00 50.63 ? 3722 HOH M O 1 HETATM 5197 O O . HOH MA 11 . ? 31.112 80.251 32.766 1.00 26.23 ? 3723 HOH M O 1 HETATM 5198 O O . HOH MA 11 . ? 36.931 77.559 37.150 1.00 41.52 ? 3724 HOH M O 1 HETATM 5199 O O . HOH MA 11 . ? 68.490 123.983 37.860 1.00 42.11 ? 3725 HOH M O 1 HETATM 5200 O O . HOH MA 11 . ? 70.793 118.059 46.925 1.00 16.22 ? 3726 HOH M O 1 HETATM 5201 O O . HOH MA 11 . ? 70.738 116.875 44.764 1.00 40.64 ? 3727 HOH M O 1 HETATM 5202 O O . HOH MA 11 . ? 72.212 114.903 43.418 1.00 39.62 ? 3728 HOH M O 1 HETATM 5203 O O . HOH MA 11 . ? 28.072 127.797 27.483 1.00 43.33 ? 3729 HOH M O 1 HETATM 5204 O O . HOH MA 11 . ? 25.080 132.715 32.770 1.00 38.70 ? 3730 HOH M O 1 HETATM 5205 O O . HOH MA 11 . ? 30.774 133.590 30.492 1.00 45.89 ? 3731 HOH M O 1 HETATM 5206 O O . HOH MA 11 . ? 27.130 128.727 34.797 1.00 48.09 ? 3732 HOH M O 1 HETATM 5207 O O . HOH MA 11 . ? 61.371 135.993 74.168 1.00 39.32 ? 3733 HOH M O 1 HETATM 5208 O O . HOH MA 11 . ? 50.628 114.916 43.123 1.00 22.88 ? 3734 HOH M O 1 HETATM 5209 O O . HOH MA 11 . ? 48.871 121.646 43.778 1.00 60.35 ? 3735 HOH M O 1 HETATM 5210 O O . HOH MA 11 . ? 48.011 119.953 36.860 1.00 28.91 ? 3736 HOH M O 1 HETATM 5211 O O . HOH MA 11 . ? 44.429 119.531 46.389 1.00 17.22 ? 3737 HOH M O 1 HETATM 5212 O O . HOH MA 11 . ? 64.012 99.089 46.059 1.00 53.67 ? 3738 HOH M O 1 HETATM 5213 O O . HOH MA 11 . ? 68.774 103.307 43.400 1.00 44.79 ? 3739 HOH M O 1 HETATM 5214 O O . HOH MA 11 . ? 67.970 103.975 48.311 1.00 19.77 ? 3740 HOH M O 1 HETATM 5215 O O . HOH MA 11 . ? 66.338 99.813 48.999 1.00 36.35 ? 3741 HOH M O 1 HETATM 5216 O O . HOH MA 11 . ? 65.077 95.033 62.715 1.00 42.36 ? 3742 HOH M O 1 HETATM 5217 O O . HOH MA 11 . ? 68.548 95.924 62.867 1.00 39.11 ? 3743 HOH M O 1 HETATM 5218 O O . HOH MA 11 . ? 27.081 135.142 38.619 1.00 35.02 ? 3744 HOH M O 1 HETATM 5219 O O . HOH MA 11 . ? 25.251 137.644 42.698 1.00 51.70 ? 3745 HOH M O 1 HETATM 5220 O O . HOH MA 11 . ? 26.497 130.988 40.145 1.00 34.95 ? 3746 HOH M O 1 HETATM 5221 O O . HOH MA 11 . ? 23.883 133.417 44.734 1.00 37.90 ? 3747 HOH M O 1 HETATM 5222 O O . HOH MA 11 . ? 28.402 136.853 43.961 1.00 21.93 ? 3748 HOH M O 1 HETATM 5223 O O . HOH MA 11 . ? 39.428 111.011 27.142 1.00 18.47 ? 3749 HOH M O 1 HETATM 5224 O O . HOH MA 11 . ? 37.005 107.256 21.900 1.00 41.60 ? 3750 HOH M O 1 HETATM 5225 O O . HOH MA 11 . ? 36.379 106.557 27.585 1.00 33.09 ? 3751 HOH M O 1 HETATM 5226 O O . HOH MA 11 . ? 34.203 108.783 24.847 1.00 20.80 ? 3752 HOH M O 1 HETATM 5227 O O . HOH MA 11 . ? 59.195 101.777 77.507 1.00 43.48 ? 3753 HOH M O 1 HETATM 5228 O O . HOH MA 11 . ? 55.200 103.943 77.151 1.00 34.91 ? 3754 HOH M O 1 HETATM 5229 O O . HOH MA 11 . ? 70.218 124.986 46.829 1.00 35.55 ? 3755 HOH M O 1 HETATM 5230 O O . HOH MA 11 . ? 33.719 110.843 17.443 1.00 39.35 ? 3756 HOH M O 1 HETATM 5231 O O . HOH MA 11 . ? 30.029 115.412 18.552 1.00 37.70 ? 3757 HOH M O 1 HETATM 5232 O O . HOH MA 11 . ? 68.192 112.416 54.543 1.00 19.11 ? 3758 HOH M O 1 HETATM 5233 O O . HOH MA 11 . ? 36.413 106.850 78.030 1.00 42.10 ? 3759 HOH M O 1 HETATM 5234 O O . HOH MA 11 . ? 32.373 106.756 79.736 1.00 16.06 ? 3760 HOH M O 1 HETATM 5235 O O . HOH MA 11 . ? 31.790 100.337 74.605 1.00 40.94 ? 3761 HOH M O 1 HETATM 5236 O O . HOH MA 11 . ? 30.924 116.769 71.253 1.00 37.20 ? 3762 HOH M O 1 HETATM 5237 O O . HOH MA 11 . ? 30.020 114.116 74.176 1.00 39.48 ? 3763 HOH M O 1 HETATM 5238 O O . HOH MA 11 . ? 36.488 113.350 72.566 1.00 34.83 ? 3764 HOH M O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 1 ? ? ? M . n A 1 2 GLU 2 2 ? ? ? M . n A 1 3 GLU 3 3 3 GLU GLU M . n A 1 4 ILE 4 4 4 ILE ILE M . n A 1 5 THR 5 5 5 THR THR M . n A 1 6 CYS 6 6 6 CYS CYS M . n A 1 7 GLN 7 7 7 GLN GLN M . n A 1 8 GLU 8 8 8 GLU GLU M . n A 1 9 ASN 9 9 9 ASN ASN M . n A 1 10 LEU 10 10 10 LEU LEU M . n A 1 11 PRO 11 11 11 PRO PRO M . n A 1 12 PHE 12 12 12 PHE PHE M . n A 1 13 THR 13 13 13 THR THR M . n A 1 14 CYS 14 14 14 CYS CYS M . n A 1 15 GLY 15 15 15 GLY GLY M . n A 1 16 ASN 16 16 16 ASN ASN M . n A 1 17 THR 17 17 17 THR THR M . n A 1 18 ASP 18 18 18 ASP ASP M . n A 1 19 ALA 19 19 19 ALA ALA M . n A 1 20 LEU 20 20 20 LEU LEU M . n A 1 21 ASN 21 21 21 ASN ASN M . n A 1 22 SER 22 22 22 SER SER M . n A 1 23 SER 23 23 23 SER SER M . n A 1 24 SER 24 24 24 SER SER M . n A 1 25 PHE 25 25 25 PHE PHE M . n A 1 26 SER 26 26 26 SER SER M . n A 1 27 SER 27 27 27 SER SER M . n A 1 28 ASP 28 28 28 ASP ASP M . n A 1 29 PHE 29 29 29 PHE PHE M . n A 1 30 ILE 30 30 30 ILE ILE M . n A 1 31 PHE 31 31 31 PHE PHE M . n A 1 32 GLY 32 32 32 GLY GLY M . n A 1 33 VAL 33 33 33 VAL VAL M . n A 1 34 ALA 34 34 34 ALA ALA M . n A 1 35 SER 35 35 35 SER SER M . n A 1 36 SER 36 36 36 SER SER M . n A 1 37 ALA 37 37 37 ALA ALA M . n A 1 38 TYR 38 38 38 TYR TYR M . n A 1 39 GLN 39 39 39 GLN GLN M . n A 1 40 ILE 40 40 40 ILE ILE M . n A 1 41 GLU 41 41 41 GLU GLU M . n A 1 42 GLY 42 42 42 GLY GLY M . n A 1 43 THR 43 43 43 THR THR M . n A 1 44 ILE 44 44 44 ILE ILE M . n A 1 45 GLY 45 45 45 GLY GLY M . n A 1 46 ARG 46 46 46 ARG ARG M . n A 1 47 GLY 47 47 47 GLY GLY M . n A 1 48 LEU 48 48 48 LEU LEU M . n A 1 49 ASN 49 49 49 ASN ASN M . n A 1 50 ILE 50 50 50 ILE ILE M . n A 1 51 TRP 51 51 51 TRP TRP M . n A 1 52 ASP 52 52 52 ASP ASP M . n A 1 53 GLY 53 53 53 GLY GLY M . n A 1 54 PHE 54 54 54 PHE PHE M . n A 1 55 THR 55 55 55 THR THR M . n A 1 56 HIS 56 56 56 HIS HIS M . n A 1 57 ARG 57 57 57 ARG ARG M . n A 1 58 TYR 58 58 58 TYR TYR M . n A 1 59 PRO 59 59 59 PRO PRO M . n A 1 60 ASN 60 60 60 ASN ASN M . n A 1 61 LYS 61 61 61 LYS LYS M . n A 1 62 SER 62 62 62 SER SER M . n A 1 63 GLY 63 63 63 GLY GLY M . n A 1 64 PRO 64 64 64 PRO PRO M . n A 1 65 ASP 65 65 65 ASP ASP M . n A 1 66 HIS 66 66 66 HIS HIS M . n A 1 67 GLY 67 67 67 GLY GLY M . n A 1 68 ASN 68 68 68 ASN ASN M . n A 1 69 GLY 69 69 69 GLY GLY M . n A 1 70 ASP 70 70 70 ASP ASP M . n A 1 71 THR 71 71 71 THR THR M . n A 1 72 THR 72 72 72 THR THR M . n A 1 73 CYS 73 73 73 CYS CYS M . n A 1 74 ASP 74 74 74 ASP ASP M . n A 1 75 SER 75 75 75 SER SER M . n A 1 76 PHE 76 76 76 PHE PHE M . n A 1 77 SER 77 77 77 SER SER M . n A 1 78 TYR 78 78 78 TYR TYR M . n A 1 79 TRP 79 79 79 TRP TRP M . n A 1 80 GLN 80 80 80 GLN GLN M . n A 1 81 LYS 81 81 81 LYS LYS M . n A 1 82 ASP 82 82 82 ASP ASP M . n A 1 83 ILE 83 83 83 ILE ILE M . n A 1 84 ASP 84 84 84 ASP ASP M . n A 1 85 VAL 85 85 85 VAL VAL M . n A 1 86 LEU 86 86 86 LEU LEU M . n A 1 87 ASP 87 87 87 ASP ASP M . n A 1 88 GLU 88 88 88 GLU GLU M . n A 1 89 LEU 89 89 89 LEU LEU M . n A 1 90 ASN 90 90 90 ASN ASN M . n A 1 91 ALA 91 91 91 ALA ALA M . n A 1 92 THR 92 92 92 THR THR M . n A 1 93 GLY 93 93 93 GLY GLY M . n A 1 94 TYR 94 94 94 TYR TYR M . n A 1 95 ARG 95 95 95 ARG ARG M . n A 1 96 PHE 96 96 96 PHE PHE M . n A 1 97 SER 97 97 97 SER SER M . n A 1 98 ILE 98 98 98 ILE ILE M . n A 1 99 ALA 99 99 99 ALA ALA M . n A 1 100 TRP 100 100 100 TRP TRP M . n A 1 101 SER 101 101 101 SER SER M . n A 1 102 ARG 102 102 102 ARG ARG M . n A 1 103 ILE 103 103 103 ILE ILE M . n A 1 104 ILE 104 104 104 ILE ILE M . n A 1 105 PRO 105 105 105 PRO PRO M . n A 1 106 ARG 106 106 106 ARG ARG M . n A 1 107 GLY 107 107 107 GLY GLY M . n A 1 108 LYS 108 108 108 LYS LYS M . n A 1 109 ARG 109 109 109 ARG ARG M . n A 1 110 SER 110 110 110 SER SER M . n A 1 111 ARG 111 111 111 ARG ARG M . n A 1 112 GLY 112 112 112 GLY GLY M . n A 1 113 VAL 113 113 113 VAL VAL M . n A 1 114 ASN 114 114 114 ASN ASN M . n A 1 115 GLU 115 115 115 GLU GLU M . n A 1 116 LYS 116 116 116 LYS LYS M . n A 1 117 GLY 117 117 117 GLY GLY M . n A 1 118 ILE 118 118 118 ILE ILE M . n A 1 119 ASP 119 119 119 ASP ASP M . n A 1 120 TYR 120 120 120 TYR TYR M . n A 1 121 TYR 121 121 121 TYR TYR M . n A 1 122 HIS 122 122 122 HIS HIS M . n A 1 123 GLY 123 123 123 GLY GLY M . n A 1 124 LEU 124 124 124 LEU LEU M . n A 1 125 ILE 125 125 125 ILE ILE M . n A 1 126 SER 126 126 126 SER SER M . n A 1 127 GLY 127 127 127 GLY GLY M . n A 1 128 LEU 128 128 128 LEU LEU M . n A 1 129 ILE 129 129 129 ILE ILE M . n A 1 130 LYS 130 130 130 LYS LYS M . n A 1 131 LYS 131 131 131 LYS LYS M . n A 1 132 GLY 132 132 132 GLY GLY M . n A 1 133 ILE 133 133 133 ILE ILE M . n A 1 134 THR 134 134 134 THR THR M . n A 1 135 PRO 135 135 135 PRO PRO M . n A 1 136 PHE 136 136 136 PHE PHE M . n A 1 137 VAL 137 137 137 VAL VAL M . n A 1 138 THR 138 138 138 THR THR M . n A 1 139 LEU 139 139 139 LEU LEU M . n A 1 140 PHE 140 140 140 PHE PHE M . n A 1 141 HIS 141 141 141 HIS HIS M . n A 1 142 TRP 142 142 142 TRP TRP M . n A 1 143 ASP 143 143 143 ASP ASP M . n A 1 144 LEU 144 144 144 LEU LEU M . n A 1 145 PRO 145 145 145 PRO PRO M . n A 1 146 GLN 146 146 146 GLN GLN M . n A 1 147 THR 147 147 147 THR THR M . n A 1 148 LEU 148 148 148 LEU LEU M . n A 1 149 GLN 149 149 149 GLN GLN M . n A 1 150 ASP 150 150 150 ASP ASP M . n A 1 151 GLU 151 151 151 GLU GLU M . n A 1 152 TYR 152 152 152 TYR TYR M . n A 1 153 GLU 153 153 153 GLU GLU M . n A 1 154 GLY 154 154 154 GLY GLY M . n A 1 155 PHE 155 155 155 PHE PHE M . n A 1 156 LEU 156 156 156 LEU LEU M . n A 1 157 ASP 157 157 157 ASP ASP M . n A 1 158 PRO 158 158 158 PRO PRO M . n A 1 159 GLN 159 159 159 GLN GLN M . n A 1 160 ILE 160 160 160 ILE ILE M . n A 1 161 ILE 161 161 161 ILE ILE M . n A 1 162 ASP 162 162 162 ASP ASP M . n A 1 163 ASP 163 163 163 ASP ASP M . n A 1 164 PHE 164 164 164 PHE PHE M . n A 1 165 LYS 165 165 165 LYS LYS M . n A 1 166 ASP 166 166 166 ASP ASP M . n A 1 167 TYR 167 167 167 TYR TYR M . n A 1 168 ALA 168 168 168 ALA ALA M . n A 1 169 ASP 169 169 169 ASP ASP M . n A 1 170 LEU 170 170 170 LEU LEU M . n A 1 171 CYS 171 171 171 CYS CYS M . n A 1 172 PHE 172 172 172 PHE PHE M . n A 1 173 GLU 173 173 173 GLU GLU M . n A 1 174 GLU 174 174 174 GLU GLU M . n A 1 175 PHE 175 175 175 PHE PHE M . n A 1 176 GLY 176 176 176 GLY GLY M . n A 1 177 ASP 177 177 177 ASP ASP M . n A 1 178 SER 178 178 178 SER SER M . n A 1 179 VAL 179 179 179 VAL VAL M . n A 1 180 LYS 180 180 180 LYS LYS M . n A 1 181 TYR 181 181 181 TYR TYR M . n A 1 182 TRP 182 182 182 TRP TRP M . n A 1 183 LEU 183 183 183 LEU LEU M . n A 1 184 THR 184 184 184 THR THR M . n A 1 185 ILE 185 185 185 ILE ILE M . n A 1 186 ASN 186 186 186 ASN ASN M . n A 1 187 GLN 187 187 187 GLN GLN M . n A 1 188 LEU 188 188 188 LEU LEU M . n A 1 189 TYR 189 189 189 TYR TYR M . n A 1 190 SER 190 190 190 SER SER M . n A 1 191 VAL 191 191 191 VAL VAL M . n A 1 192 PRO 192 192 192 PRO PRO M . n A 1 193 THR 193 193 193 THR THR M . n A 1 194 ARG 194 194 194 ARG ARG M . n A 1 195 GLY 195 195 195 GLY GLY M . n A 1 196 TYR 196 196 196 TYR TYR M . n A 1 197 GLY 197 197 197 GLY GLY M . n A 1 198 SER 198 198 198 SER SER M . n A 1 199 ALA 199 199 199 ALA ALA M . n A 1 200 LEU 200 200 200 LEU LEU M . n A 1 201 ASP 201 201 201 ASP ASP M . n A 1 202 ALA 202 202 202 ALA ALA M . n A 1 203 PRO 203 203 203 PRO PRO M . n A 1 204 GLY 204 204 204 GLY GLY M . n A 1 205 ARG 205 205 205 ARG ARG M . n A 1 206 CYS 206 206 206 CYS CYS M . n A 1 207 SER 207 207 207 SER SER M . n A 1 208 PRO 208 208 208 PRO PRO M . n A 1 209 THR 209 209 209 THR THR M . n A 1 210 VAL 210 210 210 VAL VAL M . n A 1 211 ASP 211 211 211 ASP ASP M . n A 1 212 PRO 212 212 212 PRO PRO M . n A 1 213 SER 213 213 213 SER SER M . n A 1 214 CYS 214 214 214 CYS CYS M . n A 1 215 TYR 215 215 215 TYR TYR M . n A 1 216 ALA 216 216 216 ALA ALA M . n A 1 217 GLY 217 217 217 GLY GLY M . n A 1 218 ASN 218 218 218 ASN ASN M . n A 1 219 SER 219 219 219 SER SER M . n A 1 220 SER 220 220 220 SER SER M . n A 1 221 THR 221 221 221 THR THR M . n A 1 222 GLU 222 222 222 GLU GLU M . n A 1 223 PRO 223 223 223 PRO PRO M . n A 1 224 TYR 224 224 224 TYR TYR M . n A 1 225 ILE 225 225 225 ILE ILE M . n A 1 226 VAL 226 226 226 VAL VAL M . n A 1 227 ALA 227 227 227 ALA ALA M . n A 1 228 HIS 228 228 228 HIS HIS M . n A 1 229 HIS 229 229 229 HIS HIS M . n A 1 230 GLN 230 230 230 GLN GLN M . n A 1 231 LEU 231 231 231 LEU LEU M . n A 1 232 LEU 232 232 232 LEU LEU M . n A 1 233 ALA 233 233 233 ALA ALA M . n A 1 234 HIS 234 234 234 HIS HIS M . n A 1 235 ALA 235 235 235 ALA ALA M . n A 1 236 LYS 236 236 236 LYS LYS M . n A 1 237 VAL 237 237 237 VAL VAL M . n A 1 238 VAL 238 238 238 VAL VAL M . n A 1 239 ASP 239 239 239 ASP ASP M . n A 1 240 LEU 240 240 240 LEU LEU M . n A 1 241 TYR 241 241 241 TYR TYR M . n A 1 242 ARG 242 242 242 ARG ARG M . n A 1 243 LYS 243 243 243 LYS LYS M . n A 1 244 ASN 244 244 244 ASN ASN M . n A 1 245 TYR 245 245 245 TYR TYR M . n A 1 246 THR 246 246 246 THR THR M . n A 1 247 HIS 247 247 247 HIS HIS M . n A 1 248 GLN 248 248 248 GLN GLN M . n A 1 249 GLY 249 249 249 GLY GLY M . n A 1 250 GLY 250 250 250 GLY GLY M . n A 1 251 LYS 251 251 251 LYS LYS M . n A 1 252 ILE 252 252 252 ILE ILE M . n A 1 253 GLY 253 253 253 GLY GLY M . n A 1 254 PRO 254 254 254 PRO PRO M . n A 1 255 THR 255 255 255 THR THR M . n A 1 256 MET 256 256 256 MET MET M . n A 1 257 ILE 257 257 257 ILE ILE M . n A 1 258 THR 258 258 258 THR THR M . n A 1 259 ARG 259 259 259 ARG ARG M . n A 1 260 TRP 260 260 260 TRP TRP M . n A 1 261 PHE 261 261 261 PHE PHE M . n A 1 262 LEU 262 262 262 LEU LEU M . n A 1 263 PRO 263 263 263 PRO PRO M . n A 1 264 TYR 264 264 264 TYR TYR M . n A 1 265 ASN 265 265 265 ASN ASN M . n A 1 266 ASP 266 266 266 ASP ASP M . n A 1 267 THR 267 267 267 THR THR M . n A 1 268 ASP 268 268 268 ASP ASP M . n A 1 269 ARG 269 269 269 ARG ARG M . n A 1 270 HIS 270 270 270 HIS HIS M . n A 1 271 SER 271 271 271 SER SER M . n A 1 272 ILE 272 272 272 ILE ILE M . n A 1 273 ALA 273 273 273 ALA ALA M . n A 1 274 ALA 274 274 274 ALA ALA M . n A 1 275 THR 275 275 275 THR THR M . n A 1 276 GLU 276 276 276 GLU GLU M . n A 1 277 ARG 277 277 277 ARG ARG M . n A 1 278 MET 278 278 278 MET MET M . n A 1 279 LYS 279 279 279 LYS LYS M . n A 1 280 GLU 280 280 280 GLU GLU M . n A 1 281 PHE 281 281 281 PHE PHE M . n A 1 282 PHE 282 282 282 PHE PHE M . n A 1 283 LEU 283 283 283 LEU LEU M . n A 1 284 GLY 284 284 284 GLY GLY M . n A 1 285 TRP 285 285 285 TRP TRP M . n A 1 286 PHE 286 286 286 PHE PHE M . n A 1 287 MET 287 287 287 MET MET M . n A 1 288 GLY 288 288 288 GLY GLY M . n A 1 289 PRO 289 289 289 PRO PRO M . n A 1 290 LEU 290 290 290 LEU LEU M . n A 1 291 THR 291 291 291 THR THR M . n A 1 292 ASN 292 292 292 ASN ASN M . n A 1 293 GLY 293 293 293 GLY GLY M . n A 1 294 THR 294 294 294 THR THR M . n A 1 295 TYR 295 295 295 TYR TYR M . n A 1 296 PRO 296 296 296 PRO PRO M . n A 1 297 GLN 297 297 297 GLN GLN M . n A 1 298 ILE 298 298 298 ILE ILE M . n A 1 299 MET 299 299 299 MET MET M . n A 1 300 ILE 300 300 300 ILE ILE M . n A 1 301 ASP 301 301 301 ASP ASP M . n A 1 302 THR 302 302 302 THR THR M . n A 1 303 VAL 303 303 303 VAL VAL M . n A 1 304 GLY 304 304 304 GLY GLY M . n A 1 305 GLU 305 305 305 GLU GLU M . n A 1 306 ARG 306 306 306 ARG ARG M . n A 1 307 LEU 307 307 307 LEU LEU M . n A 1 308 PRO 308 308 308 PRO PRO M . n A 1 309 SER 309 309 309 SER SER M . n A 1 310 PHE 310 310 310 PHE PHE M . n A 1 311 SER 311 311 311 SER SER M . n A 1 312 PRO 312 312 312 PRO PRO M . n A 1 313 GLU 313 313 313 GLU GLU M . n A 1 314 GLU 314 314 314 GLU GLU M . n A 1 315 SER 315 315 315 SER SER M . n A 1 316 ASN 316 316 316 ASN ASN M . n A 1 317 LEU 317 317 317 LEU LEU M . n A 1 318 VAL 318 318 318 VAL VAL M . n A 1 319 LYS 319 319 319 LYS LYS M . n A 1 320 GLY 320 320 320 GLY GLY M . n A 1 321 SER 321 321 321 SER SER M . n A 1 322 TYR 322 322 322 TYR TYR M . n A 1 323 ASP 323 323 323 ASP ASP M . n A 1 324 PHE 324 324 324 PHE PHE M . n A 1 325 LEU 325 325 325 LEU LEU M . n A 1 326 GLY 326 326 326 GLY GLY M . n A 1 327 LEU 327 327 327 LEU LEU M . n A 1 328 ASN 328 328 328 ASN ASN M . n A 1 329 TYR 329 329 329 TYR TYR M . n A 1 330 TYR 330 330 330 TYR TYR M . n A 1 331 PHE 331 331 331 PHE PHE M . n A 1 332 THR 332 332 332 THR THR M . n A 1 333 GLN 333 333 333 GLN GLN M . n A 1 334 TYR 334 334 334 TYR TYR M . n A 1 335 ALA 335 335 335 ALA ALA M . n A 1 336 GLN 336 336 336 GLN GLN M . n A 1 337 PRO 337 337 337 PRO PRO M . n A 1 338 SER 338 338 338 SER SER M . n A 1 339 PRO 339 339 339 PRO PRO M . n A 1 340 ASN 340 340 340 ASN ASN M . n A 1 341 PRO 341 341 341 PRO PRO M . n A 1 342 VAL 342 342 342 VAL VAL M . n A 1 343 ASN 343 343 343 ASN ASN M . n A 1 344 SER 344 344 344 SER SER M . n A 1 345 THR 345 345 345 THR THR M . n A 1 346 ASN 346 346 346 ASN ASN M . n A 1 347 HIS 347 347 347 HIS HIS M . n A 1 348 THR 348 348 348 THR THR M . n A 1 349 ALA 349 349 349 ALA ALA M . n A 1 350 MET 350 350 350 MET MET M . n A 1 351 MET 351 351 351 MET MET M . n A 1 352 ASP 352 352 352 ASP ASP M . n A 1 353 ALA 353 353 353 ALA ALA M . n A 1 354 GLY 354 354 354 GLY GLY M . n A 1 355 ALA 355 355 355 ALA ALA M . n A 1 356 LYS 356 356 356 LYS LYS M . n A 1 357 LEU 357 357 357 LEU LEU M . n A 1 358 THR 358 358 358 THR THR M . n A 1 359 TYR 359 359 359 TYR TYR M . n A 1 360 ILE 360 360 360 ILE ILE M . n A 1 361 ASN 361 361 361 ASN ASN M . n A 1 362 ALA 362 362 362 ALA ALA M . n A 1 363 SER 363 363 363 SER SER M . n A 1 364 GLY 364 364 364 GLY GLY M . n A 1 365 HIS 365 365 365 HIS HIS M . n A 1 366 TYR 366 366 366 TYR TYR M . n A 1 367 ILE 367 367 367 ILE ILE M . n A 1 368 GLY 368 368 368 GLY GLY M . n A 1 369 PRO 369 369 369 PRO PRO M . n A 1 370 LEU 370 370 370 LEU LEU M . n A 1 371 PHE 371 371 371 PHE PHE M . n A 1 372 GLU 372 372 372 GLU GLU M . n A 1 373 LYS 373 373 373 LYS LYS M . n A 1 374 ASP 374 374 374 ASP ASP M . n A 1 375 LYS 375 375 375 LYS LYS M . n A 1 376 ALA 376 376 376 ALA ALA M . n A 1 377 ASP 377 377 377 ASP ASP M . n A 1 378 SER 378 378 378 SER SER M . n A 1 379 THR 379 379 379 THR THR M . n A 1 380 ASP 380 380 380 ASP ASP M . n A 1 381 ASN 381 381 381 ASN ASN M . n A 1 382 ILE 382 382 382 ILE ILE M . n A 1 383 TYR 383 383 383 TYR TYR M . n A 1 384 TYR 384 384 384 TYR TYR M . n A 1 385 TYR 385 385 385 TYR TYR M . n A 1 386 PRO 386 386 386 PRO PRO M . n A 1 387 LYS 387 387 387 LYS LYS M . n A 1 388 GLY 388 388 388 GLY GLY M . n A 1 389 ILE 389 389 389 ILE ILE M . n A 1 390 TYR 390 390 390 TYR TYR M . n A 1 391 SER 391 391 391 SER SER M . n A 1 392 VAL 392 392 392 VAL VAL M . n A 1 393 MET 393 393 393 MET MET M . n A 1 394 ASP 394 394 394 ASP ASP M . n A 1 395 TYR 395 395 395 TYR TYR M . n A 1 396 PHE 396 396 396 PHE PHE M . n A 1 397 LYS 397 397 397 LYS LYS M . n A 1 398 ASN 398 398 398 ASN ASN M . n A 1 399 LYS 399 399 399 LYS LYS M . n A 1 400 TYR 400 400 400 TYR TYR M . n A 1 401 TYR 401 401 401 TYR TYR M . n A 1 402 ASN 402 402 402 ASN ASN M . n A 1 403 PRO 403 403 403 PRO PRO M . n A 1 404 LEU 404 404 404 LEU LEU M . n A 1 405 ILE 405 405 405 ILE ILE M . n A 1 406 TYR 406 406 406 TYR TYR M . n A 1 407 VAL 407 407 407 VAL VAL M . n A 1 408 THR 408 408 408 THR THR M . n A 1 409 GLU 409 409 409 GLU GLU M . n A 1 410 ASN 410 410 410 ASN ASN M . n A 1 411 GLY 411 411 411 GLY GLY M . n A 1 412 ILE 412 412 412 ILE ILE M . n A 1 413 SER 413 413 413 SER SER M . n A 1 414 THR 414 414 414 THR THR M . n A 1 415 PRO 415 415 415 PRO PRO M . n A 1 416 GLY 416 416 416 GLY GLY M . n A 1 417 ASP 417 417 417 ASP ASP M . n A 1 418 GLU 418 418 418 GLU GLU M . n A 1 419 ASN 419 419 419 ASN ASN M . n A 1 420 ARG 420 420 420 ARG ARG M . n A 1 421 ASN 421 421 421 ASN ASN M . n A 1 422 GLN 422 422 422 GLN GLN M . n A 1 423 SER 423 423 423 SER SER M . n A 1 424 MET 424 424 424 MET MET M . n A 1 425 LEU 425 425 425 LEU LEU M . n A 1 426 ASP 426 426 426 ASP ASP M . n A 1 427 TYR 427 427 427 TYR TYR M . n A 1 428 THR 428 428 428 THR THR M . n A 1 429 ARG 429 429 429 ARG ARG M . n A 1 430 ILE 430 430 430 ILE ILE M . n A 1 431 ASP 431 431 431 ASP ASP M . n A 1 432 TYR 432 432 432 TYR TYR M . n A 1 433 LEU 433 433 433 LEU LEU M . n A 1 434 CYS 434 434 434 CYS CYS M . n A 1 435 SER 435 435 435 SER SER M . n A 1 436 HIS 436 436 436 HIS HIS M . n A 1 437 LEU 437 437 437 LEU LEU M . n A 1 438 CYS 438 438 438 CYS CYS M . n A 1 439 PHE 439 439 439 PHE PHE M . n A 1 440 LEU 440 440 440 LEU LEU M . n A 1 441 ASN 441 441 441 ASN ASN M . n A 1 442 LYS 442 442 442 LYS LYS M . n A 1 443 VAL 443 443 443 VAL VAL M . n A 1 444 ILE 444 444 444 ILE ILE M . n A 1 445 LYS 445 445 445 LYS LYS M . n A 1 446 GLU 446 446 446 GLU GLU M . n A 1 447 LYS 447 447 447 LYS LYS M . n A 1 448 ASP 448 448 448 ASP ASP M . n A 1 449 VAL 449 449 449 VAL VAL M . n A 1 450 ASN 450 450 450 ASN ASN M . n A 1 451 VAL 451 451 451 VAL VAL M . n A 1 452 LYS 452 452 452 LYS LYS M . n A 1 453 GLY 453 453 453 GLY GLY M . n A 1 454 TYR 454 454 454 TYR TYR M . n A 1 455 LEU 455 455 455 LEU LEU M . n A 1 456 ALA 456 456 456 ALA ALA M . n A 1 457 TRP 457 457 457 TRP TRP M . n A 1 458 ALA 458 458 458 ALA ALA M . n A 1 459 LEU 459 459 459 LEU LEU M . n A 1 460 GLY 460 460 460 GLY GLY M . n A 1 461 ASP 461 461 461 ASP ASP M . n A 1 462 ASN 462 462 462 ASN ASN M . n A 1 463 TYR 463 463 463 TYR TYR M . n A 1 464 GLU 464 464 464 GLU GLU M . n A 1 465 PHE 465 465 465 PHE PHE M . n A 1 466 ASN 466 466 466 ASN ASN M . n A 1 467 LYS 467 467 467 LYS LYS M . n A 1 468 GLY 468 468 468 GLY GLY M . n A 1 469 PHE 469 469 469 PHE PHE M . n A 1 470 THR 470 470 470 THR THR M . n A 1 471 VAL 471 471 471 VAL VAL M . n A 1 472 ARG 472 472 472 ARG ARG M . n A 1 473 PHE 473 473 473 PHE PHE M . n A 1 474 GLY 474 474 474 GLY GLY M . n A 1 475 LEU 475 475 475 LEU LEU M . n A 1 476 SER 476 476 476 SER SER M . n A 1 477 TYR 477 477 477 TYR TYR M . n A 1 478 ILE 478 478 478 ILE ILE M . n A 1 479 ASP 479 479 479 ASP ASP M . n A 1 480 TRP 480 480 480 TRP TRP M . n A 1 481 ASN 481 481 481 ASN ASN M . n A 1 482 ASN 482 482 482 ASN ASN M . n A 1 483 VAL 483 483 483 VAL VAL M . n A 1 484 THR 484 484 484 THR THR M . n A 1 485 ASP 485 485 485 ASP ASP M . n A 1 486 ARG 486 486 486 ARG ARG M . n A 1 487 ASP 487 487 487 ASP ASP M . n A 1 488 LEU 488 488 488 LEU LEU M . n A 1 489 LYS 489 489 489 LYS LYS M . n A 1 490 LYS 490 490 490 LYS LYS M . n A 1 491 SER 491 491 491 SER SER M . n A 1 492 GLY 492 492 492 GLY GLY M . n A 1 493 GLN 493 493 493 GLN GLN M . n A 1 494 TRP 494 494 494 TRP TRP M . n A 1 495 TYR 495 495 495 TYR TYR M . n A 1 496 GLN 496 496 496 GLN GLN M . n A 1 497 SER 497 497 497 SER SER M . n A 1 498 PHE 498 498 498 PHE PHE M . n A 1 499 ILE 499 499 499 ILE ILE M . n A 1 500 SER 500 500 500 SER SER M . n A 1 501 PRO 501 501 501 PRO PRO M . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 901 901 NAG NAG M . C 2 NAG 1 911 911 NAG NAG M . D 2 NAG 2 913 913 NAG NAG M . E 2 NAG 1 921 921 NAG NAG M . F 2 NAG 2 923 923 NAG NAG M . G 2 NAG 1 931 931 NAG NAG M . H 2 NAG 1 941 941 NAG NAG M . I 3 FUC 2 942 942 FUC FUC M . J 2 NAG 3 943 943 NAG NAG M . K 4 BMA 4 944 944 BMA BMA M . L 5 XYP 5 945 945 XYP XYP M . M 2 NAG 1 951 951 NAG NAG M . N 3 FUC 2 952 952 FUC FUC M . O 2 NAG 3 953 953 NAG NAG M . P 4 BMA 4 954 954 BMA BMA M . Q 5 XYP 5 955 955 XYP XYP M . R 6 MAN 6 956 956 MAN MAN M . S 6 MAN 7 957 957 MAN MAN M . T 2 NAG 1 961 961 NAG NAG M . U 2 NAG 2 963 963 NAG NAG M . V 2 NAG 1 971 971 NAG NAG M . W 2 NAG 1 981 981 NAG NAG M . X 2 NAG 2 983 983 NAG NAG M . Y 2 NAG 1 991 991 NAG NAG M . Z 7 E18 1 1501 1501 E18 E18 M . AA 8 ZN 1 1502 1502 ZN ZN M . BA 9 SO4 1 1503 1503 SO4 SO4 M . CA 9 SO4 1 1504 1504 SO4 SO4 M . DA 9 SO4 1 1505 1505 SO4 SO4 M . EA 9 SO4 1 1506 1506 SO4 SO4 M . FA 9 SO4 1 1507 1507 SO4 SO4 M . GA 9 SO4 1 1508 1508 SO4 SO4 M . HA 9 SO4 1 1509 1509 SO4 SO4 M . IA 10 GOL 1 2511 2511 GOL GOL M . JA 10 GOL 1 2512 2512 GOL GOL M . KA 10 GOL 1 2513 2513 GOL GOL M . LA 10 GOL 1 2514 2514 GOL GOL M . MA 11 HOH 1 3001 3001 HOH HOH M . MA 11 HOH 2 3002 3002 HOH HOH M . MA 11 HOH 3 3003 3003 HOH HOH M . MA 11 HOH 4 3004 3004 HOH HOH M . MA 11 HOH 5 3005 3005 HOH HOH M . MA 11 HOH 6 3006 3006 HOH HOH M . MA 11 HOH 7 3007 3007 HOH HOH M . MA 11 HOH 8 3008 3008 HOH HOH M . MA 11 HOH 9 3009 3009 HOH HOH M . MA 11 HOH 10 3010 3010 HOH HOH M . MA 11 HOH 11 3011 3011 HOH HOH M . MA 11 HOH 12 3012 3012 HOH HOH M . MA 11 HOH 13 3013 3013 HOH HOH M . MA 11 HOH 14 3014 3014 HOH HOH M . MA 11 HOH 15 3015 3015 HOH HOH M . MA 11 HOH 16 3016 3016 HOH HOH M . MA 11 HOH 17 3017 3017 HOH HOH M . MA 11 HOH 18 3018 3018 HOH HOH M . MA 11 HOH 19 3019 3019 HOH HOH M . MA 11 HOH 20 3020 3020 HOH HOH M . MA 11 HOH 21 3021 3021 HOH HOH M . MA 11 HOH 22 3022 3022 HOH HOH M . MA 11 HOH 23 3023 3023 HOH HOH M . MA 11 HOH 24 3024 3024 HOH HOH M . MA 11 HOH 25 3025 3025 HOH HOH M . MA 11 HOH 26 3026 3026 HOH HOH M . MA 11 HOH 27 3027 3027 HOH HOH M . MA 11 HOH 28 3028 3028 HOH HOH M . MA 11 HOH 29 3029 3029 HOH HOH M . MA 11 HOH 30 3030 3030 HOH HOH M . MA 11 HOH 31 3031 3031 HOH HOH M . MA 11 HOH 32 3032 3032 HOH HOH M . MA 11 HOH 33 3033 3033 HOH HOH M . MA 11 HOH 34 3034 3034 HOH HOH M . MA 11 HOH 35 3035 3035 HOH HOH M . MA 11 HOH 36 3036 3036 HOH HOH M . MA 11 HOH 37 3037 3037 HOH HOH M . MA 11 HOH 38 3038 3038 HOH HOH M . MA 11 HOH 39 3039 3039 HOH HOH M . MA 11 HOH 40 3040 3040 HOH HOH M . MA 11 HOH 41 3041 3041 HOH HOH M . MA 11 HOH 42 3042 3042 HOH HOH M . MA 11 HOH 43 3043 3043 HOH HOH M . MA 11 HOH 44 3044 3044 HOH HOH M . MA 11 HOH 45 3045 3045 HOH HOH M . MA 11 HOH 46 3046 3046 HOH HOH M . MA 11 HOH 47 3047 3047 HOH HOH M . MA 11 HOH 48 3048 3048 HOH HOH M . MA 11 HOH 49 3049 3049 HOH HOH M . MA 11 HOH 50 3050 3050 HOH HOH M . MA 11 HOH 51 3051 3051 HOH HOH M . MA 11 HOH 52 3052 3052 HOH HOH M . MA 11 HOH 53 3053 3053 HOH HOH M . MA 11 HOH 54 3054 3054 HOH HOH M . MA 11 HOH 55 3055 3055 HOH HOH M . MA 11 HOH 56 3056 3056 HOH HOH M . MA 11 HOH 57 3057 3057 HOH HOH M . MA 11 HOH 58 3058 3058 HOH HOH M . MA 11 HOH 59 3059 3059 HOH HOH M . MA 11 HOH 60 3060 3060 HOH HOH M . MA 11 HOH 61 3061 3061 HOH HOH M . MA 11 HOH 62 3062 3062 HOH HOH M . MA 11 HOH 63 3063 3063 HOH HOH M . MA 11 HOH 64 3064 3064 HOH HOH M . MA 11 HOH 65 3065 3065 HOH HOH M . MA 11 HOH 66 3066 3066 HOH HOH M . MA 11 HOH 67 3067 3067 HOH HOH M . MA 11 HOH 68 3068 3068 HOH HOH M . MA 11 HOH 69 3069 3069 HOH HOH M . MA 11 HOH 70 3070 3070 HOH HOH M . MA 11 HOH 71 3071 3071 HOH HOH M . MA 11 HOH 72 3072 3072 HOH HOH M . MA 11 HOH 73 3073 3073 HOH HOH M . MA 11 HOH 74 3074 3074 HOH HOH M . MA 11 HOH 75 3075 3075 HOH HOH M . MA 11 HOH 76 3076 3076 HOH HOH M . MA 11 HOH 77 3077 3077 HOH HOH M . MA 11 HOH 78 3078 3078 HOH HOH M . MA 11 HOH 79 3079 3079 HOH HOH M . MA 11 HOH 80 3080 3080 HOH HOH M . MA 11 HOH 81 3081 3081 HOH HOH M . MA 11 HOH 82 3082 3082 HOH HOH M . MA 11 HOH 83 3083 3083 HOH HOH M . MA 11 HOH 84 3084 3084 HOH HOH M . MA 11 HOH 85 3085 3085 HOH HOH M . MA 11 HOH 86 3086 3086 HOH HOH M . MA 11 HOH 87 3087 3087 HOH HOH M . MA 11 HOH 88 3088 3088 HOH HOH M . MA 11 HOH 89 3089 3089 HOH HOH M . MA 11 HOH 90 3090 3090 HOH HOH M . MA 11 HOH 91 3091 3091 HOH HOH M . MA 11 HOH 92 3092 3092 HOH HOH M . MA 11 HOH 93 3093 3093 HOH HOH M . MA 11 HOH 94 3094 3094 HOH HOH M . MA 11 HOH 95 3095 3095 HOH HOH M . MA 11 HOH 96 3096 3096 HOH HOH M . MA 11 HOH 97 3097 3097 HOH HOH M . MA 11 HOH 98 3098 3098 HOH HOH M . MA 11 HOH 99 3099 3099 HOH HOH M . MA 11 HOH 100 3100 3100 HOH HOH M . MA 11 HOH 101 3101 3101 HOH HOH M . MA 11 HOH 102 3102 3102 HOH HOH M . MA 11 HOH 103 3103 3103 HOH HOH M . MA 11 HOH 104 3104 3104 HOH HOH M . MA 11 HOH 105 3105 3105 HOH HOH M . MA 11 HOH 106 3106 3106 HOH HOH M . MA 11 HOH 107 3107 3107 HOH HOH M . MA 11 HOH 108 3108 3108 HOH HOH M . MA 11 HOH 109 3109 3109 HOH HOH M . MA 11 HOH 110 3110 3110 HOH HOH M . MA 11 HOH 111 3111 3111 HOH HOH M . MA 11 HOH 112 3112 3112 HOH HOH M . MA 11 HOH 113 3113 3113 HOH HOH M . MA 11 HOH 114 3114 3114 HOH HOH M . MA 11 HOH 115 3115 3115 HOH HOH M . MA 11 HOH 116 3116 3116 HOH HOH M . MA 11 HOH 117 3117 3117 HOH HOH M . MA 11 HOH 118 3118 3118 HOH HOH M . MA 11 HOH 119 3119 3119 HOH HOH M . MA 11 HOH 120 3120 3120 HOH HOH M . MA 11 HOH 121 3121 3121 HOH HOH M . MA 11 HOH 122 3122 3122 HOH HOH M . MA 11 HOH 123 3123 3123 HOH HOH M . MA 11 HOH 124 3124 3124 HOH HOH M . MA 11 HOH 125 3125 3125 HOH HOH M . MA 11 HOH 126 3126 3126 HOH HOH M . MA 11 HOH 127 3127 3127 HOH HOH M . MA 11 HOH 128 3128 3128 HOH HOH M . MA 11 HOH 129 3129 3129 HOH HOH M . MA 11 HOH 130 3130 3130 HOH HOH M . MA 11 HOH 131 3131 3131 HOH HOH M . MA 11 HOH 132 3132 3132 HOH HOH M . MA 11 HOH 133 3133 3133 HOH HOH M . MA 11 HOH 134 3134 3134 HOH HOH M . MA 11 HOH 135 3135 3135 HOH HOH M . MA 11 HOH 136 3136 3136 HOH HOH M . MA 11 HOH 137 3137 3137 HOH HOH M . MA 11 HOH 138 3138 3138 HOH HOH M . MA 11 HOH 139 3139 3139 HOH HOH M . MA 11 HOH 140 3140 3140 HOH HOH M . MA 11 HOH 141 3141 3141 HOH HOH M . MA 11 HOH 142 3142 3142 HOH HOH M . MA 11 HOH 143 3143 3143 HOH HOH M . MA 11 HOH 144 3144 3144 HOH HOH M . MA 11 HOH 145 3145 3145 HOH HOH M . MA 11 HOH 146 3146 3146 HOH HOH M . MA 11 HOH 147 3147 3147 HOH HOH M . MA 11 HOH 148 3148 3148 HOH HOH M . MA 11 HOH 149 3149 3149 HOH HOH M . MA 11 HOH 150 3150 3150 HOH HOH M . MA 11 HOH 151 3151 3151 HOH HOH M . MA 11 HOH 152 3152 3152 HOH HOH M . MA 11 HOH 153 3153 3153 HOH HOH M . MA 11 HOH 154 3154 3154 HOH HOH M . MA 11 HOH 155 3155 3155 HOH HOH M . MA 11 HOH 156 3156 3156 HOH HOH M . MA 11 HOH 157 3157 3157 HOH HOH M . MA 11 HOH 158 3158 3158 HOH HOH M . MA 11 HOH 159 3159 3159 HOH HOH M . MA 11 HOH 160 3160 3160 HOH HOH M . MA 11 HOH 161 3161 3161 HOH HOH M . MA 11 HOH 162 3162 3162 HOH HOH M . MA 11 HOH 163 3163 3163 HOH HOH M . MA 11 HOH 164 3164 3164 HOH HOH M . MA 11 HOH 165 3165 3165 HOH HOH M . MA 11 HOH 166 3166 3166 HOH HOH M . MA 11 HOH 167 3167 3167 HOH HOH M . MA 11 HOH 168 3168 3168 HOH HOH M . MA 11 HOH 169 3169 3169 HOH HOH M . MA 11 HOH 170 3170 3170 HOH HOH M . MA 11 HOH 171 3171 3171 HOH HOH M . MA 11 HOH 172 3172 3172 HOH HOH M . MA 11 HOH 173 3173 3173 HOH HOH M . MA 11 HOH 174 3174 3174 HOH HOH M . MA 11 HOH 175 3175 3175 HOH HOH M . MA 11 HOH 176 3176 3176 HOH HOH M . MA 11 HOH 177 3177 3177 HOH HOH M . MA 11 HOH 178 3178 3178 HOH HOH M . MA 11 HOH 179 3179 3179 HOH HOH M . MA 11 HOH 180 3180 3180 HOH HOH M . MA 11 HOH 181 3181 3181 HOH HOH M . MA 11 HOH 182 3182 3182 HOH HOH M . MA 11 HOH 183 3183 3183 HOH HOH M . MA 11 HOH 184 3184 3184 HOH HOH M . MA 11 HOH 185 3185 3185 HOH HOH M . MA 11 HOH 186 3186 3186 HOH HOH M . MA 11 HOH 187 3187 3187 HOH HOH M . MA 11 HOH 188 3188 3188 HOH HOH M . MA 11 HOH 189 3189 3189 HOH HOH M . MA 11 HOH 190 3190 3190 HOH HOH M . MA 11 HOH 191 3191 3191 HOH HOH M . MA 11 HOH 192 3192 3192 HOH HOH M . MA 11 HOH 193 3193 3193 HOH HOH M . MA 11 HOH 194 3194 3194 HOH HOH M . MA 11 HOH 195 3195 3195 HOH HOH M . MA 11 HOH 196 3196 3196 HOH HOH M . MA 11 HOH 197 3197 3197 HOH HOH M . MA 11 HOH 198 3198 3198 HOH HOH M . MA 11 HOH 199 3199 3199 HOH HOH M . MA 11 HOH 200 3200 3200 HOH HOH M . MA 11 HOH 201 3201 3201 HOH HOH M . MA 11 HOH 202 3202 3202 HOH HOH M . MA 11 HOH 203 3203 3203 HOH HOH M . MA 11 HOH 204 3204 3204 HOH HOH M . MA 11 HOH 205 3205 3205 HOH HOH M . MA 11 HOH 206 3206 3206 HOH HOH M . MA 11 HOH 207 3207 3207 HOH HOH M . MA 11 HOH 208 3208 3208 HOH HOH M . MA 11 HOH 209 3209 3209 HOH HOH M . MA 11 HOH 210 3210 3210 HOH HOH M . MA 11 HOH 211 3211 3211 HOH HOH M . MA 11 HOH 212 3212 3212 HOH HOH M . MA 11 HOH 213 3213 3213 HOH HOH M . MA 11 HOH 214 3214 3214 HOH HOH M . MA 11 HOH 215 3215 3215 HOH HOH M . MA 11 HOH 216 3216 3216 HOH HOH M . MA 11 HOH 217 3217 3217 HOH HOH M . MA 11 HOH 218 3218 3218 HOH HOH M . MA 11 HOH 219 3219 3219 HOH HOH M . MA 11 HOH 220 3220 3220 HOH HOH M . MA 11 HOH 221 3221 3221 HOH HOH M . MA 11 HOH 222 3222 3222 HOH HOH M . MA 11 HOH 223 3223 3223 HOH HOH M . MA 11 HOH 224 3224 3224 HOH HOH M . MA 11 HOH 225 3225 3225 HOH HOH M . MA 11 HOH 226 3226 3226 HOH HOH M . MA 11 HOH 227 3227 3227 HOH HOH M . MA 11 HOH 228 3228 3228 HOH HOH M . MA 11 HOH 229 3229 3229 HOH HOH M . MA 11 HOH 230 3230 3230 HOH HOH M . MA 11 HOH 231 3231 3231 HOH HOH M . MA 11 HOH 232 3232 3232 HOH HOH M . MA 11 HOH 233 3233 3233 HOH HOH M . MA 11 HOH 234 3234 3234 HOH HOH M . MA 11 HOH 235 3235 3235 HOH HOH M . MA 11 HOH 236 3236 3236 HOH HOH M . MA 11 HOH 237 3237 3237 HOH HOH M . MA 11 HOH 238 3238 3238 HOH HOH M . MA 11 HOH 239 3239 3239 HOH HOH M . MA 11 HOH 240 3240 3240 HOH HOH M . MA 11 HOH 241 3241 3241 HOH HOH M . MA 11 HOH 242 3242 3242 HOH HOH M . MA 11 HOH 243 3243 3243 HOH HOH M . MA 11 HOH 244 3244 3244 HOH HOH M . MA 11 HOH 245 3245 3245 HOH HOH M . MA 11 HOH 246 3246 3246 HOH HOH M . MA 11 HOH 247 3247 3247 HOH HOH M . MA 11 HOH 248 3248 3248 HOH HOH M . MA 11 HOH 249 3249 3249 HOH HOH M . MA 11 HOH 250 3250 3250 HOH HOH M . MA 11 HOH 251 3251 3251 HOH HOH M . MA 11 HOH 252 3252 3252 HOH HOH M . MA 11 HOH 253 3253 3253 HOH HOH M . MA 11 HOH 254 3254 3254 HOH HOH M . MA 11 HOH 255 3255 3255 HOH HOH M . MA 11 HOH 256 3256 3256 HOH HOH M . MA 11 HOH 257 3257 3257 HOH HOH M . MA 11 HOH 258 3258 3258 HOH HOH M . MA 11 HOH 259 3259 3259 HOH HOH M . MA 11 HOH 260 3260 3260 HOH HOH M . MA 11 HOH 261 3261 3261 HOH HOH M . MA 11 HOH 262 3262 3262 HOH HOH M . MA 11 HOH 263 3263 3263 HOH HOH M . MA 11 HOH 264 3264 3264 HOH HOH M . MA 11 HOH 265 3265 3265 HOH HOH M . MA 11 HOH 266 3266 3266 HOH HOH M . MA 11 HOH 267 3267 3267 HOH HOH M . MA 11 HOH 268 3268 3268 HOH HOH M . MA 11 HOH 269 3269 3269 HOH HOH M . MA 11 HOH 270 3270 3270 HOH HOH M . MA 11 HOH 271 3271 3271 HOH HOH M . MA 11 HOH 272 3272 3272 HOH HOH M . MA 11 HOH 273 3273 3273 HOH HOH M . MA 11 HOH 274 3274 3274 HOH HOH M . MA 11 HOH 275 3275 3275 HOH HOH M . MA 11 HOH 276 3276 3276 HOH HOH M . MA 11 HOH 277 3277 3277 HOH HOH M . MA 11 HOH 278 3278 3278 HOH HOH M . MA 11 HOH 279 3279 3279 HOH HOH M . MA 11 HOH 280 3280 3280 HOH HOH M . MA 11 HOH 281 3281 3281 HOH HOH M . MA 11 HOH 282 3282 3282 HOH HOH M . MA 11 HOH 283 3283 3283 HOH HOH M . MA 11 HOH 284 3284 3284 HOH HOH M . MA 11 HOH 285 3285 3285 HOH HOH M . MA 11 HOH 286 3286 3286 HOH HOH M . MA 11 HOH 287 3287 3287 HOH HOH M . MA 11 HOH 288 3288 3288 HOH HOH M . MA 11 HOH 289 3289 3289 HOH HOH M . MA 11 HOH 290 3290 3290 HOH HOH M . MA 11 HOH 291 3291 3291 HOH HOH M . MA 11 HOH 292 3292 3292 HOH HOH M . MA 11 HOH 293 3293 3293 HOH HOH M . MA 11 HOH 294 3294 3294 HOH HOH M . MA 11 HOH 295 3295 3295 HOH HOH M . MA 11 HOH 296 3296 3296 HOH HOH M . MA 11 HOH 297 3297 3297 HOH HOH M . MA 11 HOH 298 3298 3298 HOH HOH M . MA 11 HOH 299 3299 3299 HOH HOH M . MA 11 HOH 300 3300 3300 HOH HOH M . MA 11 HOH 301 3301 3301 HOH HOH M . MA 11 HOH 302 3302 3302 HOH HOH M . MA 11 HOH 303 3303 3303 HOH HOH M . MA 11 HOH 304 3304 3304 HOH HOH M . MA 11 HOH 305 3305 3305 HOH HOH M . MA 11 HOH 306 3306 3306 HOH HOH M . MA 11 HOH 307 3307 3307 HOH HOH M . MA 11 HOH 308 3308 3308 HOH HOH M . MA 11 HOH 309 3309 3309 HOH HOH M . MA 11 HOH 310 3310 3310 HOH HOH M . MA 11 HOH 311 3311 3311 HOH HOH M . MA 11 HOH 312 3312 3312 HOH HOH M . MA 11 HOH 313 3313 3313 HOH HOH M . MA 11 HOH 314 3314 3314 HOH HOH M . MA 11 HOH 315 3315 3315 HOH HOH M . MA 11 HOH 316 3316 3316 HOH HOH M . MA 11 HOH 317 3317 3317 HOH HOH M . MA 11 HOH 318 3318 3318 HOH HOH M . MA 11 HOH 319 3319 3319 HOH HOH M . MA 11 HOH 320 3320 3320 HOH HOH M . MA 11 HOH 321 3321 3321 HOH HOH M . MA 11 HOH 322 3322 3322 HOH HOH M . MA 11 HOH 323 3323 3323 HOH HOH M . MA 11 HOH 324 3324 3324 HOH HOH M . MA 11 HOH 325 3325 3325 HOH HOH M . MA 11 HOH 326 3326 3326 HOH HOH M . MA 11 HOH 327 3327 3327 HOH HOH M . MA 11 HOH 328 3328 3328 HOH HOH M . MA 11 HOH 329 3329 3329 HOH HOH M . MA 11 HOH 330 3330 3330 HOH HOH M . MA 11 HOH 331 3331 3331 HOH HOH M . MA 11 HOH 332 3332 3332 HOH HOH M . MA 11 HOH 333 3333 3333 HOH HOH M . MA 11 HOH 334 3334 3334 HOH HOH M . MA 11 HOH 335 3335 3335 HOH HOH M . MA 11 HOH 336 3336 3336 HOH HOH M . MA 11 HOH 337 3337 3337 HOH HOH M . MA 11 HOH 338 3338 3338 HOH HOH M . MA 11 HOH 339 3339 3339 HOH HOH M . MA 11 HOH 340 3340 3340 HOH HOH M . MA 11 HOH 341 3341 3341 HOH HOH M . MA 11 HOH 342 3342 3342 HOH HOH M . MA 11 HOH 343 3343 3343 HOH HOH M . MA 11 HOH 344 3344 3344 HOH HOH M . MA 11 HOH 345 3345 3345 HOH HOH M . MA 11 HOH 346 3346 3346 HOH HOH M . MA 11 HOH 347 3347 3347 HOH HOH M . MA 11 HOH 348 3348 3348 HOH HOH M . MA 11 HOH 349 3349 3349 HOH HOH M . MA 11 HOH 350 3350 3350 HOH HOH M . MA 11 HOH 351 3351 3351 HOH HOH M . MA 11 HOH 352 3352 3352 HOH HOH M . MA 11 HOH 353 3353 3353 HOH HOH M . MA 11 HOH 354 3354 3354 HOH HOH M . MA 11 HOH 355 3355 3355 HOH HOH M . MA 11 HOH 356 3356 3356 HOH HOH M . MA 11 HOH 357 3357 3357 HOH HOH M . MA 11 HOH 358 3358 3358 HOH HOH M . MA 11 HOH 359 3359 3359 HOH HOH M . MA 11 HOH 360 3360 3360 HOH HOH M . MA 11 HOH 361 3361 3361 HOH HOH M . MA 11 HOH 362 3362 3362 HOH HOH M . MA 11 HOH 363 3363 3363 HOH HOH M . MA 11 HOH 364 3364 3364 HOH HOH M . MA 11 HOH 365 3365 3365 HOH HOH M . MA 11 HOH 366 3366 3366 HOH HOH M . MA 11 HOH 367 3367 3367 HOH HOH M . MA 11 HOH 368 3368 3368 HOH HOH M . MA 11 HOH 369 3369 3369 HOH HOH M . MA 11 HOH 370 3370 3370 HOH HOH M . MA 11 HOH 371 3371 3371 HOH HOH M . MA 11 HOH 372 3372 3372 HOH HOH M . MA 11 HOH 373 3373 3373 HOH HOH M . MA 11 HOH 374 3374 3374 HOH HOH M . MA 11 HOH 375 3375 3375 HOH HOH M . MA 11 HOH 376 3376 3376 HOH HOH M . MA 11 HOH 377 3377 3377 HOH HOH M . MA 11 HOH 378 3378 3378 HOH HOH M . MA 11 HOH 379 3379 3379 HOH HOH M . MA 11 HOH 380 3380 3380 HOH HOH M . MA 11 HOH 381 3381 3381 HOH HOH M . MA 11 HOH 382 3382 3382 HOH HOH M . MA 11 HOH 383 3383 3383 HOH HOH M . MA 11 HOH 384 3384 3384 HOH HOH M . MA 11 HOH 385 3385 3385 HOH HOH M . MA 11 HOH 386 3386 3386 HOH HOH M . MA 11 HOH 387 3387 3387 HOH HOH M . MA 11 HOH 388 3388 3388 HOH HOH M . MA 11 HOH 389 3389 3389 HOH HOH M . MA 11 HOH 390 3390 3390 HOH HOH M . MA 11 HOH 391 3391 3391 HOH HOH M . MA 11 HOH 392 3392 3392 HOH HOH M . MA 11 HOH 393 3393 3393 HOH HOH M . MA 11 HOH 394 3394 3394 HOH HOH M . MA 11 HOH 395 3395 3395 HOH HOH M . MA 11 HOH 396 3396 3396 HOH HOH M . MA 11 HOH 397 3397 3397 HOH HOH M . MA 11 HOH 398 3398 3398 HOH HOH M . MA 11 HOH 399 3399 3399 HOH HOH M . MA 11 HOH 400 3400 3400 HOH HOH M . MA 11 HOH 401 3401 3401 HOH HOH M . MA 11 HOH 402 3402 3402 HOH HOH M . MA 11 HOH 403 3403 3403 HOH HOH M . MA 11 HOH 404 3404 3404 HOH HOH M . MA 11 HOH 405 3405 3405 HOH HOH M . MA 11 HOH 406 3406 3406 HOH HOH M . MA 11 HOH 407 3407 3407 HOH HOH M . MA 11 HOH 408 3408 3408 HOH HOH M . MA 11 HOH 409 3409 3409 HOH HOH M . MA 11 HOH 410 3410 3410 HOH HOH M . MA 11 HOH 411 3411 3411 HOH HOH M . MA 11 HOH 412 3412 3412 HOH HOH M . MA 11 HOH 413 3413 3413 HOH HOH M . MA 11 HOH 414 3414 3414 HOH HOH M . MA 11 HOH 415 3415 3415 HOH HOH M . MA 11 HOH 416 3416 3416 HOH HOH M . MA 11 HOH 417 3417 3417 HOH HOH M . MA 11 HOH 418 3418 3418 HOH HOH M . MA 11 HOH 419 3419 3419 HOH HOH M . MA 11 HOH 420 3420 3420 HOH HOH M . MA 11 HOH 421 3421 3421 HOH HOH M . MA 11 HOH 422 3422 3422 HOH HOH M . MA 11 HOH 423 3423 3423 HOH HOH M . MA 11 HOH 424 3424 3424 HOH HOH M . MA 11 HOH 425 3425 3425 HOH HOH M . MA 11 HOH 426 3426 3426 HOH HOH M . MA 11 HOH 427 3427 3427 HOH HOH M . MA 11 HOH 428 3428 3428 HOH HOH M . MA 11 HOH 429 3429 3429 HOH HOH M . MA 11 HOH 430 3430 3430 HOH HOH M . MA 11 HOH 431 3431 3431 HOH HOH M . MA 11 HOH 432 3432 3432 HOH HOH M . MA 11 HOH 433 3433 3433 HOH HOH M . MA 11 HOH 434 3434 3434 HOH HOH M . MA 11 HOH 435 3435 3435 HOH HOH M . MA 11 HOH 436 3436 3436 HOH HOH M . MA 11 HOH 437 3437 3437 HOH HOH M . MA 11 HOH 438 3438 3438 HOH HOH M . MA 11 HOH 439 3439 3439 HOH HOH M . MA 11 HOH 440 3440 3440 HOH HOH M . MA 11 HOH 441 3441 3441 HOH HOH M . MA 11 HOH 442 3442 3442 HOH HOH M . MA 11 HOH 443 3443 3443 HOH HOH M . MA 11 HOH 444 3444 3444 HOH HOH M . MA 11 HOH 445 3445 3445 HOH HOH M . MA 11 HOH 446 3446 3446 HOH HOH M . MA 11 HOH 447 3447 3447 HOH HOH M . MA 11 HOH 448 3448 3448 HOH HOH M . MA 11 HOH 449 3449 3449 HOH HOH M . MA 11 HOH 450 3450 3450 HOH HOH M . MA 11 HOH 451 3451 3451 HOH HOH M . MA 11 HOH 452 3452 3452 HOH HOH M . MA 11 HOH 453 3453 3453 HOH HOH M . MA 11 HOH 454 3454 3454 HOH HOH M . MA 11 HOH 455 3455 3455 HOH HOH M . MA 11 HOH 456 3456 3456 HOH HOH M . MA 11 HOH 457 3457 3457 HOH HOH M . MA 11 HOH 458 3458 3458 HOH HOH M . MA 11 HOH 459 3459 3459 HOH HOH M . MA 11 HOH 460 3460 3460 HOH HOH M . MA 11 HOH 461 3461 3461 HOH HOH M . MA 11 HOH 462 3462 3462 HOH HOH M . MA 11 HOH 463 3463 3463 HOH HOH M . MA 11 HOH 464 3464 3464 HOH HOH M . MA 11 HOH 465 3465 3465 HOH HOH M . MA 11 HOH 466 3466 3466 HOH HOH M . MA 11 HOH 467 3467 3467 HOH HOH M . MA 11 HOH 468 3468 3468 HOH HOH M . MA 11 HOH 469 3469 3469 HOH HOH M . MA 11 HOH 470 3470 3470 HOH HOH M . MA 11 HOH 471 3471 3471 HOH HOH M . MA 11 HOH 472 3472 3472 HOH HOH M . MA 11 HOH 473 3473 3473 HOH HOH M . MA 11 HOH 474 3474 3474 HOH HOH M . MA 11 HOH 475 3475 3475 HOH HOH M . MA 11 HOH 476 3476 3476 HOH HOH M . MA 11 HOH 477 3477 3477 HOH HOH M . MA 11 HOH 478 3478 3478 HOH HOH M . MA 11 HOH 479 3479 3479 HOH HOH M . MA 11 HOH 480 3480 3480 HOH HOH M . MA 11 HOH 481 3481 3481 HOH HOH M . MA 11 HOH 482 3482 3482 HOH HOH M . MA 11 HOH 483 3483 3483 HOH HOH M . MA 11 HOH 484 3484 3484 HOH HOH M . MA 11 HOH 485 3485 3485 HOH HOH M . MA 11 HOH 486 3486 3486 HOH HOH M . MA 11 HOH 487 3487 3487 HOH HOH M . MA 11 HOH 488 3488 3488 HOH HOH M . MA 11 HOH 489 3489 3489 HOH HOH M . MA 11 HOH 490 3490 3490 HOH HOH M . MA 11 HOH 491 3491 3491 HOH HOH M . MA 11 HOH 492 3492 3492 HOH HOH M . MA 11 HOH 493 3493 3493 HOH HOH M . MA 11 HOH 494 3494 3494 HOH HOH M . MA 11 HOH 495 3495 3495 HOH HOH M . MA 11 HOH 496 3496 3496 HOH HOH M . MA 11 HOH 497 3497 3497 HOH HOH M . MA 11 HOH 498 3498 3498 HOH HOH M . MA 11 HOH 499 3499 3499 HOH HOH M . MA 11 HOH 500 3500 3500 HOH HOH M . MA 11 HOH 501 3501 3501 HOH HOH M . MA 11 HOH 502 3502 3502 HOH HOH M . MA 11 HOH 503 3503 3503 HOH HOH M . MA 11 HOH 504 3504 3504 HOH HOH M . MA 11 HOH 505 3505 3505 HOH HOH M . MA 11 HOH 506 3506 3506 HOH HOH M . MA 11 HOH 507 3507 3507 HOH HOH M . MA 11 HOH 508 3508 3508 HOH HOH M . MA 11 HOH 509 3509 3509 HOH HOH M . MA 11 HOH 510 3510 3510 HOH HOH M . MA 11 HOH 511 3511 3511 HOH HOH M . MA 11 HOH 512 3512 3512 HOH HOH M . MA 11 HOH 513 3513 3513 HOH HOH M . MA 11 HOH 514 3514 3514 HOH HOH M . MA 11 HOH 515 3515 3515 HOH HOH M . MA 11 HOH 516 3516 3516 HOH HOH M . MA 11 HOH 517 3517 3517 HOH HOH M . MA 11 HOH 518 3518 3518 HOH HOH M . MA 11 HOH 519 3519 3519 HOH HOH M . MA 11 HOH 520 3520 3520 HOH HOH M . MA 11 HOH 521 3521 3521 HOH HOH M . MA 11 HOH 522 3522 3522 HOH HOH M . MA 11 HOH 523 3523 3523 HOH HOH M . MA 11 HOH 524 3524 3524 HOH HOH M . MA 11 HOH 525 3525 3525 HOH HOH M . MA 11 HOH 526 3526 3526 HOH HOH M . MA 11 HOH 527 3527 3527 HOH HOH M . MA 11 HOH 528 3528 3528 HOH HOH M . MA 11 HOH 529 3529 3529 HOH HOH M . MA 11 HOH 530 3530 3530 HOH HOH M . MA 11 HOH 531 3531 3531 HOH HOH M . MA 11 HOH 532 3532 3532 HOH HOH M . MA 11 HOH 533 3533 3533 HOH HOH M . MA 11 HOH 534 3534 3534 HOH HOH M . MA 11 HOH 535 3535 3535 HOH HOH M . MA 11 HOH 536 3536 3536 HOH HOH M . MA 11 HOH 537 3537 3537 HOH HOH M . MA 11 HOH 538 3538 3538 HOH HOH M . MA 11 HOH 539 3539 3539 HOH HOH M . MA 11 HOH 540 3540 3540 HOH HOH M . MA 11 HOH 541 3541 3541 HOH HOH M . MA 11 HOH 542 3542 3542 HOH HOH M . MA 11 HOH 543 3543 3543 HOH HOH M . MA 11 HOH 544 3544 3544 HOH HOH M . MA 11 HOH 545 3545 3545 HOH HOH M . MA 11 HOH 546 3546 3546 HOH HOH M . MA 11 HOH 547 3547 3547 HOH HOH M . MA 11 HOH 548 3548 3548 HOH HOH M . MA 11 HOH 549 3549 3549 HOH HOH M . MA 11 HOH 550 3550 3550 HOH HOH M . MA 11 HOH 551 3551 3551 HOH HOH M . MA 11 HOH 552 3552 3552 HOH HOH M . MA 11 HOH 553 3553 3553 HOH HOH M . MA 11 HOH 554 3554 3554 HOH HOH M . MA 11 HOH 555 3555 3555 HOH HOH M . MA 11 HOH 556 3556 3556 HOH HOH M . MA 11 HOH 557 3557 3557 HOH HOH M . MA 11 HOH 558 3558 3558 HOH HOH M . MA 11 HOH 559 3559 3559 HOH HOH M . MA 11 HOH 560 3560 3560 HOH HOH M . MA 11 HOH 561 3561 3561 HOH HOH M . MA 11 HOH 562 3562 3562 HOH HOH M . MA 11 HOH 563 3563 3563 HOH HOH M . MA 11 HOH 564 3564 3564 HOH HOH M . MA 11 HOH 565 3565 3565 HOH HOH M . MA 11 HOH 566 3566 3566 HOH HOH M . MA 11 HOH 567 3567 3567 HOH HOH M . MA 11 HOH 568 3568 3568 HOH HOH M . MA 11 HOH 569 3569 3569 HOH HOH M . MA 11 HOH 570 3570 3570 HOH HOH M . MA 11 HOH 571 3571 3571 HOH HOH M . MA 11 HOH 572 3572 3572 HOH HOH M . MA 11 HOH 573 3573 3573 HOH HOH M . MA 11 HOH 574 3574 3574 HOH HOH M . MA 11 HOH 575 3575 3575 HOH HOH M . MA 11 HOH 576 3576 3576 HOH HOH M . MA 11 HOH 577 3577 3577 HOH HOH M . MA 11 HOH 578 3578 3578 HOH HOH M . MA 11 HOH 579 3579 3579 HOH HOH M . MA 11 HOH 580 3580 3580 HOH HOH M . MA 11 HOH 581 3581 3581 HOH HOH M . MA 11 HOH 582 3582 3582 HOH HOH M . MA 11 HOH 583 3583 3583 HOH HOH M . MA 11 HOH 584 3584 3584 HOH HOH M . MA 11 HOH 585 3585 3585 HOH HOH M . MA 11 HOH 586 3586 3586 HOH HOH M . MA 11 HOH 587 3587 3587 HOH HOH M . MA 11 HOH 588 3588 3588 HOH HOH M . MA 11 HOH 589 3589 3589 HOH HOH M . MA 11 HOH 590 3590 3590 HOH HOH M . MA 11 HOH 591 3591 3591 HOH HOH M . MA 11 HOH 592 3592 3592 HOH HOH M . MA 11 HOH 593 3593 3593 HOH HOH M . MA 11 HOH 594 3594 3594 HOH HOH M . MA 11 HOH 595 3595 3595 HOH HOH M . MA 11 HOH 596 3596 3596 HOH HOH M . MA 11 HOH 597 3597 3597 HOH HOH M . MA 11 HOH 598 3598 3598 HOH HOH M . MA 11 HOH 599 3599 3599 HOH HOH M . MA 11 HOH 600 3600 3600 HOH HOH M . MA 11 HOH 601 3601 3601 HOH HOH M . MA 11 HOH 602 3602 3602 HOH HOH M . MA 11 HOH 603 3603 3603 HOH HOH M . MA 11 HOH 604 3604 3604 HOH HOH M . MA 11 HOH 605 3605 3605 HOH HOH M . MA 11 HOH 606 3606 3606 HOH HOH M . MA 11 HOH 607 3607 3607 HOH HOH M . MA 11 HOH 608 3608 3608 HOH HOH M . MA 11 HOH 609 3609 3609 HOH HOH M . MA 11 HOH 610 3610 3610 HOH HOH M . MA 11 HOH 611 3611 3611 HOH HOH M . MA 11 HOH 612 3612 3612 HOH HOH M . MA 11 HOH 613 3613 3613 HOH HOH M . MA 11 HOH 614 3614 3614 HOH HOH M . MA 11 HOH 615 3615 3615 HOH HOH M . MA 11 HOH 616 3616 3616 HOH HOH M . MA 11 HOH 617 3617 3617 HOH HOH M . MA 11 HOH 618 3618 3618 HOH HOH M . MA 11 HOH 619 3619 3619 HOH HOH M . MA 11 HOH 620 3620 3620 HOH HOH M . MA 11 HOH 621 3621 3621 HOH HOH M . MA 11 HOH 622 3622 3622 HOH HOH M . MA 11 HOH 623 3623 3623 HOH HOH M . MA 11 HOH 624 3624 3624 HOH HOH M . MA 11 HOH 625 3625 3625 HOH HOH M . MA 11 HOH 626 3626 3626 HOH HOH M . MA 11 HOH 627 3627 3627 HOH HOH M . MA 11 HOH 628 3628 3628 HOH HOH M . MA 11 HOH 629 3629 3629 HOH HOH M . MA 11 HOH 630 3630 3630 HOH HOH M . MA 11 HOH 631 3631 3631 HOH HOH M . MA 11 HOH 632 3632 3632 HOH HOH M . MA 11 HOH 633 3633 3633 HOH HOH M . MA 11 HOH 634 3634 3634 HOH HOH M . MA 11 HOH 635 3635 3635 HOH HOH M . MA 11 HOH 636 3636 3636 HOH HOH M . MA 11 HOH 637 3637 3637 HOH HOH M . MA 11 HOH 638 3638 3638 HOH HOH M . MA 11 HOH 639 3639 3639 HOH HOH M . MA 11 HOH 640 3640 3640 HOH HOH M . MA 11 HOH 641 3641 3641 HOH HOH M . MA 11 HOH 642 3642 3642 HOH HOH M . MA 11 HOH 643 3643 3643 HOH HOH M . MA 11 HOH 644 3644 3644 HOH HOH M . MA 11 HOH 645 3645 3645 HOH HOH M . MA 11 HOH 646 3646 3646 HOH HOH M . MA 11 HOH 647 3647 3647 HOH HOH M . MA 11 HOH 648 3648 3648 HOH HOH M . MA 11 HOH 649 3649 3649 HOH HOH M . MA 11 HOH 650 3650 3650 HOH HOH M . MA 11 HOH 651 3651 3651 HOH HOH M . MA 11 HOH 652 3652 3652 HOH HOH M . MA 11 HOH 653 3653 3653 HOH HOH M . MA 11 HOH 654 3654 3654 HOH HOH M . MA 11 HOH 655 3655 3655 HOH HOH M . MA 11 HOH 656 3656 3656 HOH HOH M . MA 11 HOH 657 3657 3657 HOH HOH M . MA 11 HOH 658 3658 3658 HOH HOH M . MA 11 HOH 659 3659 3659 HOH HOH M . MA 11 HOH 660 3660 3660 HOH HOH M . MA 11 HOH 661 3661 3661 HOH HOH M . MA 11 HOH 662 3662 3662 HOH HOH M . MA 11 HOH 663 3663 3663 HOH HOH M . MA 11 HOH 664 3664 3664 HOH HOH M . MA 11 HOH 665 3665 3665 HOH HOH M . MA 11 HOH 666 3666 3666 HOH HOH M . MA 11 HOH 667 3667 3667 HOH HOH M . MA 11 HOH 668 3668 3668 HOH HOH M . MA 11 HOH 669 3669 3669 HOH HOH M . MA 11 HOH 670 3670 3670 HOH HOH M . MA 11 HOH 671 3671 3671 HOH HOH M . MA 11 HOH 672 3672 3672 HOH HOH M . MA 11 HOH 673 3673 3673 HOH HOH M . MA 11 HOH 674 3674 3674 HOH HOH M . MA 11 HOH 675 3675 3675 HOH HOH M . MA 11 HOH 676 3676 3676 HOH HOH M . MA 11 HOH 677 3677 3677 HOH HOH M . MA 11 HOH 678 3678 3678 HOH HOH M . MA 11 HOH 679 3679 3679 HOH HOH M . MA 11 HOH 680 3680 3680 HOH HOH M . MA 11 HOH 681 3681 3681 HOH HOH M . MA 11 HOH 682 3682 3682 HOH HOH M . MA 11 HOH 683 3683 3683 HOH HOH M . MA 11 HOH 684 3684 3684 HOH HOH M . MA 11 HOH 685 3685 3685 HOH HOH M . MA 11 HOH 686 3686 3686 HOH HOH M . MA 11 HOH 687 3687 3687 HOH HOH M . MA 11 HOH 688 3688 3688 HOH HOH M . MA 11 HOH 689 3689 3689 HOH HOH M . MA 11 HOH 690 3690 3690 HOH HOH M . MA 11 HOH 691 3691 3691 HOH HOH M . MA 11 HOH 692 3692 3692 HOH HOH M . MA 11 HOH 693 3693 3693 HOH HOH M . MA 11 HOH 694 3694 3694 HOH HOH M . MA 11 HOH 695 3695 3695 HOH HOH M . MA 11 HOH 696 3696 3696 HOH HOH M . MA 11 HOH 697 3697 3697 HOH HOH M . MA 11 HOH 698 3698 3698 HOH HOH M . MA 11 HOH 699 3699 3699 HOH HOH M . MA 11 HOH 700 3700 3700 HOH HOH M . MA 11 HOH 701 3701 3701 HOH HOH M . MA 11 HOH 702 3702 3702 HOH HOH M . MA 11 HOH 703 3703 3703 HOH HOH M . MA 11 HOH 704 3704 3704 HOH HOH M . MA 11 HOH 705 3705 3705 HOH HOH M . MA 11 HOH 706 3706 3706 HOH HOH M . MA 11 HOH 707 3707 3707 HOH HOH M . MA 11 HOH 708 3708 3708 HOH HOH M . MA 11 HOH 709 3709 3709 HOH HOH M . MA 11 HOH 710 3710 3710 HOH HOH M . MA 11 HOH 711 3711 3711 HOH HOH M . MA 11 HOH 712 3712 3712 HOH HOH M . MA 11 HOH 713 3713 3713 HOH HOH M . MA 11 HOH 714 3714 3714 HOH HOH M . MA 11 HOH 715 3715 3715 HOH HOH M . MA 11 HOH 716 3716 3716 HOH HOH M . MA 11 HOH 717 3717 3717 HOH HOH M . MA 11 HOH 718 3718 3718 HOH HOH M . MA 11 HOH 719 3719 3719 HOH HOH M . MA 11 HOH 720 3720 3720 HOH HOH M . MA 11 HOH 721 3721 3721 HOH HOH M . MA 11 HOH 722 3722 3722 HOH HOH M . MA 11 HOH 723 3723 3723 HOH HOH M . MA 11 HOH 724 3724 3724 HOH HOH M . MA 11 HOH 725 3725 3725 HOH HOH M . MA 11 HOH 726 3726 3726 HOH HOH M . MA 11 HOH 727 3727 3727 HOH HOH M . MA 11 HOH 728 3728 3728 HOH HOH M . MA 11 HOH 729 3729 3729 HOH HOH M . MA 11 HOH 730 3730 3730 HOH HOH M . MA 11 HOH 731 3731 3731 HOH HOH M . MA 11 HOH 732 3732 3732 HOH HOH M . MA 11 HOH 733 3733 3733 HOH HOH M . MA 11 HOH 734 3734 3734 HOH HOH M . MA 11 HOH 735 3735 3735 HOH HOH M . MA 11 HOH 736 3736 3736 HOH HOH M . MA 11 HOH 737 3737 3737 HOH HOH M . MA 11 HOH 738 3738 3738 HOH HOH M . MA 11 HOH 739 3739 3739 HOH HOH M . MA 11 HOH 740 3740 3740 HOH HOH M . MA 11 HOH 741 3741 3741 HOH HOH M . MA 11 HOH 742 3742 3742 HOH HOH M . MA 11 HOH 743 3743 3743 HOH HOH M . MA 11 HOH 744 3744 3744 HOH HOH M . MA 11 HOH 745 3745 3745 HOH HOH M . MA 11 HOH 746 3746 3746 HOH HOH M . MA 11 HOH 747 3747 3747 HOH HOH M . MA 11 HOH 748 3748 3748 HOH HOH M . MA 11 HOH 749 3749 3749 HOH HOH M . MA 11 HOH 750 3750 3750 HOH HOH M . MA 11 HOH 751 3751 3751 HOH HOH M . MA 11 HOH 752 3752 3752 HOH HOH M . MA 11 HOH 753 3753 3753 HOH HOH M . MA 11 HOH 754 3754 3754 HOH HOH M . MA 11 HOH 755 3755 3755 HOH HOH M . MA 11 HOH 756 3756 3756 HOH HOH M . MA 11 HOH 757 3757 3757 HOH HOH M . MA 11 HOH 758 3758 3758 HOH HOH M . MA 11 HOH 759 3759 3759 HOH HOH M . MA 11 HOH 760 3760 3760 HOH HOH M . MA 11 HOH 761 3761 3761 HOH HOH M . MA 11 HOH 762 3762 3762 HOH HOH M . MA 11 HOH 763 3763 3763 HOH HOH M . MA 11 HOH 764 3764 3764 HOH HOH M . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 21 M ASN 21 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 60 M ASN 60 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 90 M ASN 90 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 218 M ASN 218 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 244 M ASN 244 ? ASN 'GLYCOSYLATION SITE' 6 A ASN 265 M ASN 265 ? ASN 'GLYCOSYLATION SITE' 7 A ASN 292 M ASN 292 ? ASN 'GLYCOSYLATION SITE' 8 A ASN 346 M ASN 346 ? ASN 'GLYCOSYLATION SITE' 9 A ASN 361 M ASN 361 ? ASN 'GLYCOSYLATION SITE' 10 A ASN 482 M ASN 482 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,FA,GA,HA,IA,JA,KA,LA,MA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 16800 ? 1 MORE -92.7 ? 1 'SSA (A^2)' 40010 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 3_656 -x+1,y,-z+3/2 -1.0000000000 0.0000000000 0.0000000000 136.2450000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 121.0845000000 # loop_ _pdbx_struct_special_symmetry.id _pdbx_struct_special_symmetry.PDB_model_num _pdbx_struct_special_symmetry.auth_asym_id _pdbx_struct_special_symmetry.auth_comp_id _pdbx_struct_special_symmetry.auth_seq_id _pdbx_struct_special_symmetry.PDB_ins_code _pdbx_struct_special_symmetry.label_asym_id _pdbx_struct_special_symmetry.label_comp_id _pdbx_struct_special_symmetry.label_seq_id 1 1 M ZN 1502 ? AA ZN . 2 1 M HOH 3024 ? MA HOH . # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD2 ? A ASP 70 ? M ASP 70 ? 3_656 ZN ? AA ZN . ? M ZN 1502 ? 1_555 OD2 ? A ASP 70 ? M ASP 70 ? 1_555 95.5 ? 2 OD2 ? A ASP 70 ? M ASP 70 ? 3_656 ZN ? AA ZN . ? M ZN 1502 ? 1_555 NE2 ? A HIS 56 ? M HIS 56 ? 3_656 119.3 ? 3 OD2 ? A ASP 70 ? M ASP 70 ? 1_555 ZN ? AA ZN . ? M ZN 1502 ? 1_555 NE2 ? A HIS 56 ? M HIS 56 ? 3_656 102.8 ? 4 OD2 ? A ASP 70 ? M ASP 70 ? 3_656 ZN ? AA ZN . ? M ZN 1502 ? 1_555 NE2 ? A HIS 56 ? M HIS 56 ? 1_555 106.5 ? 5 OD2 ? A ASP 70 ? M ASP 70 ? 1_555 ZN ? AA ZN . ? M ZN 1502 ? 1_555 NE2 ? A HIS 56 ? M HIS 56 ? 1_555 118.8 ? 6 NE2 ? A HIS 56 ? M HIS 56 ? 3_656 ZN ? AA ZN . ? M ZN 1502 ? 1_555 NE2 ? A HIS 56 ? M HIS 56 ? 1_555 113.3 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-09 2 'Structure model' 1 1 2012-04-04 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 2 'Structure model' 'Derived calculations' 3 2 'Structure model' 'Non-polymer description' 4 2 'Structure model' Other 5 2 'Structure model' 'Refinement description' 6 2 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.5.0102 ? 1 MOSFLM 'data reduction' . ? 2 SCALA 'data scaling' . ? 3 # _pdbx_database_remark.id 700 _pdbx_database_remark.text ; SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED. ; # _pdbx_entry_details.entry_id 2WXD _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ;S-(N,N-DIMETHYLAMINOETHYL) PHENYLACETOTHIOHYDROXIMATE-O-SULFATE (E18): COMPOUND 8 OF SECONDARY REFERENCE ; _pdbx_entry_details.sequence_details ;SEQUENCE OBTAINED FROM ELECTRON DENSITY OF THE XRAY STRUCTURE ; # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 NZ M LYS 373 ? ? O M HOH 3539 ? ? 1.81 2 1 O M HOH 3379 ? ? O M HOH 3386 ? ? 1.82 3 1 O M HOH 3064 ? ? O M HOH 3066 ? ? 1.87 4 1 NE2 M GLN 493 ? ? O M HOH 3675 ? ? 1.92 5 1 OG M SER 126 ? B O M HOH 3244 ? ? 1.93 6 1 O M HOH 3433 ? ? O M HOH 3434 ? ? 2.03 7 1 OE2 M GLU 88 ? A O M HOH 3168 ? ? 2.07 8 1 OD1 M ASP 177 ? ? O M HOH 3324 ? ? 2.08 9 1 O M HOH 3287 ? ? O M HOH 3292 ? ? 2.10 10 1 O M HOH 3297 ? ? O M HOH 3300 ? ? 2.11 11 1 O4 M NAG 961 ? ? O5 M NAG 963 ? ? 2.16 12 1 O4 M NAG 953 ? ? O5 M BMA 954 ? ? 2.19 13 1 O M HOH 3325 ? ? O M HOH 3764 ? ? 2.19 14 1 O4 M NAG 921 ? ? O5 M NAG 923 ? ? 2.19 # loop_ _pdbx_validate_symm_contact.id _pdbx_validate_symm_contact.PDB_model_num _pdbx_validate_symm_contact.auth_atom_id_1 _pdbx_validate_symm_contact.auth_asym_id_1 _pdbx_validate_symm_contact.auth_comp_id_1 _pdbx_validate_symm_contact.auth_seq_id_1 _pdbx_validate_symm_contact.PDB_ins_code_1 _pdbx_validate_symm_contact.label_alt_id_1 _pdbx_validate_symm_contact.site_symmetry_1 _pdbx_validate_symm_contact.auth_atom_id_2 _pdbx_validate_symm_contact.auth_asym_id_2 _pdbx_validate_symm_contact.auth_comp_id_2 _pdbx_validate_symm_contact.auth_seq_id_2 _pdbx_validate_symm_contact.PDB_ins_code_2 _pdbx_validate_symm_contact.label_alt_id_2 _pdbx_validate_symm_contact.site_symmetry_2 _pdbx_validate_symm_contact.dist 1 1 O M HOH 3250 ? ? 1_555 O M HOH 3250 ? ? 4_576 1.49 2 1 O M HOH 3285 ? ? 1_555 O M HOH 3285 ? ? 3_656 1.66 3 1 O M HOH 3198 ? ? 1_555 O M HOH 3741 ? ? 3_656 2.12 4 1 O M HOH 3255 ? ? 1_555 O M HOH 3715 ? ? 6_565 2.18 5 1 O M HOH 3285 ? ? 1_555 O M HOH 3743 ? ? 3_656 2.19 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 CB M SER 24 ? ? OG M SER 24 ? ? 1.509 1.418 0.091 0.013 N 2 1 CD M GLU 151 ? ? OE2 M GLU 151 ? ? 1.176 1.252 -0.076 0.011 N 3 1 CB M SER 178 ? ? OG M SER 178 ? ? 1.537 1.418 0.119 0.013 N 4 1 CD M GLU 222 ? ? OE2 M GLU 222 ? ? 1.329 1.252 0.077 0.011 N 5 1 CE1 M TYR 264 ? ? CZ M TYR 264 ? ? 1.299 1.381 -0.082 0.013 N 6 1 CD M GLU 372 ? ? OE1 M GLU 372 ? ? 1.328 1.252 0.076 0.011 N 7 1 CZ M TYR 390 ? ? CE2 M TYR 390 ? ? 1.258 1.381 -0.123 0.013 N 8 1 CB M CYS 434 ? ? SG M CYS 434 ? ? 1.715 1.812 -0.097 0.016 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE M ARG 46 ? ? CZ M ARG 46 ? ? NH2 M ARG 46 ? ? 117.11 120.30 -3.19 0.50 N 2 1 CB M TYR 94 ? ? CG M TYR 94 ? ? CD1 M TYR 94 ? ? 116.88 121.00 -4.12 0.60 N 3 1 NE M ARG 106 ? ? CZ M ARG 106 ? ? NH2 M ARG 106 ? ? 116.61 120.30 -3.69 0.50 N 4 1 OE1 M GLU 153 ? ? CD M GLU 153 ? ? OE2 M GLU 153 ? ? 115.37 123.30 -7.93 1.20 N 5 1 NE M ARG 205 ? ? CZ M ARG 205 ? ? NH2 M ARG 205 ? ? 124.83 120.30 4.53 0.50 N 6 1 CB M TYR 215 ? ? CG M TYR 215 ? ? CD1 M TYR 215 ? ? 116.96 121.00 -4.04 0.60 N 7 1 NE M ARG 242 ? ? CZ M ARG 242 ? ? NH1 M ARG 242 ? ? 124.32 120.30 4.02 0.50 N 8 1 NE M ARG 242 ? ? CZ M ARG 242 ? ? NH2 M ARG 242 ? ? 114.40 120.30 -5.90 0.50 N 9 1 CB M ASP 266 ? ? CG M ASP 266 ? ? OD2 M ASP 266 ? ? 112.45 118.30 -5.85 0.90 N 10 1 CB M ASP 268 ? ? CG M ASP 268 ? ? OD1 M ASP 268 ? ? 126.06 118.30 7.76 0.90 N 11 1 NE M ARG 269 ? ? CZ M ARG 269 ? ? NH1 M ARG 269 ? ? 124.15 120.30 3.85 0.50 N 12 1 OE1 M GLU 280 ? ? CD M GLU 280 ? ? OE2 M GLU 280 ? ? 116.06 123.30 -7.24 1.20 N 13 1 CB M ASP 301 ? ? CG M ASP 301 ? ? OD2 M ASP 301 ? ? 112.22 118.30 -6.08 0.90 N 14 1 NE M ARG 306 ? ? CZ M ARG 306 ? ? NH1 M ARG 306 ? ? 123.45 120.30 3.15 0.50 N 15 1 CB M ASP 323 ? ? CG M ASP 323 ? ? OD2 M ASP 323 ? ? 124.10 118.30 5.80 0.90 N 16 1 CZ M TYR 334 ? ? CE2 M TYR 334 ? ? CD2 M TYR 334 ? ? 125.74 119.80 5.94 0.90 N 17 1 CB M TYR 390 ? ? CG M TYR 390 ? ? CD2 M TYR 390 ? ? 117.07 121.00 -3.93 0.60 N 18 1 NE M ARG 420 ? ? CZ M ARG 420 ? ? NH2 M ARG 420 ? ? 117.00 120.30 -3.30 0.50 N 19 1 CB M LEU 425 ? ? CG M LEU 425 ? ? CD1 M LEU 425 ? ? 98.54 111.00 -12.46 1.70 N 20 1 CB M ASP 426 ? ? CG M ASP 426 ? ? OD1 M ASP 426 ? ? 125.80 118.30 7.50 0.90 N 21 1 NE M ARG 429 ? ? CZ M ARG 429 ? ? NH2 M ARG 429 ? ? 117.24 120.30 -3.06 0.50 N 22 1 CA M CYS 434 ? ? CB M CYS 434 ? ? SG M CYS 434 ? ? 123.00 114.20 8.80 1.10 N 23 1 CB M ASP 448 ? ? CG M ASP 448 ? ? OD2 M ASP 448 ? ? 112.86 118.30 -5.44 0.90 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS M 66 ? ? 56.40 19.69 2 1 THR M 72 ? ? 44.67 -139.22 3 1 HIS M 141 ? ? -109.86 54.90 4 1 TRP M 142 ? ? 83.87 -12.95 5 1 TYR M 152 ? ? -146.30 16.64 6 1 THR M 184 ? ? -79.52 -76.92 7 1 GLN M 187 ? ? 47.21 82.44 8 1 ASN M 466 ? ? 85.05 -23.32 9 1 ASN M 482 ? ? -162.44 88.99 # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? M HOH 3030 ? 6.46 . 2 1 O ? M HOH 3031 ? 6.18 . 3 1 O ? M HOH 3046 ? 6.13 . # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 M LYS 375 ? CB ? A LYS 375 CB 2 1 Y 1 M LYS 375 ? CG ? A LYS 375 CG 3 1 Y 1 M LYS 375 ? CD ? A LYS 375 CD 4 1 Y 1 M LYS 375 ? CE ? A LYS 375 CE 5 1 Y 1 M LYS 375 ? NZ ? A LYS 375 NZ 6 1 Y 1 M ASP 417 ? CG ? A ASP 417 CG 7 1 Y 1 M ASP 417 ? OD1 ? A ASP 417 OD1 8 1 Y 1 M ASP 417 ? OD2 ? A ASP 417 OD2 9 1 Y 1 M LEU 455 ? O ? A LEU 455 O # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 M ASP 1 ? A ASP 1 2 1 Y 1 M GLU 2 ? A GLU 2 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 ALPHA-L-FUCOSE FUC 4 BETA-D-MANNOSE BMA 5 BETA-D-XYLOPYRANOSE XYP 6 ALPHA-D-MANNOSE MAN 7 '2-(DIMETHYLAMINO)ETHYL (1Z)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE' E18 8 'ZINC ION' ZN 9 'SULFATE ION' SO4 10 GLYCEROL GOL 11 water HOH #