data_2WIL # _entry.id 2WIL # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2WIL WWPDB D_1290039791 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 1EHQ unspecified 'MODEL OF (+)-COCAINE-BOUND BCHE COMPLEX' PDB 2J4C unspecified 'STRUCTURE OF HUMAN BUTYRYLCHOLINESTERASE IN COMPLEX WITH 10MM HGCL2' PDB 1P0Q unspecified 'CRYSTAL STRUCTURE OF SOMAN-AGED HUMAN BUTYRYL CHOLINESTERASE' PDB 2WIK unspecified 'NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA6' PDB 1KCJ unspecified 'MODEL OF (-)-COCAINE-BOUND (-)-COCAINE HYDROLASE COMPLEX' PDB 1P0P unspecified 'CRYSTAL STRUCTURE OF SOMAN-AGED HUMAN BUTYRYLCHOLINESTERASE IN COMPLEX WITH THE SUBSTRATE ANALOGBUTYRYLTHIOCHOLINE' PDB 2WID unspecified 'AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA1' PDB 1XLU unspecified 'X-RAY STRUCTURE OF DI-ISOPROPYL-PHOSPHORO- FLUORIDATE (DFP)INHIBITED BUTYRYLCHOLINESTERASE AFTER AGING' PDB 2WIJ unspecified 'NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5' PDB 1XLV unspecified 'ETHYLPHOSPHORYLATED BUTYRYLCHOLINESTERASE (AGED) OBTAINEDBY REACTION WITH ECHOTHIOPHATE' PDB 1EHO unspecified 'MODEL OF (-)-COCAINE-BOUND BCHE COMPLEX.' PDB 2WIF unspecified 'AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA1' PDB 1P0M unspecified 'CRYSTAL STRUCTURE OF HUMAN BUTYRYL CHOLINESTERASE INCOMPLEX WITH A CHOLINE MOLECULE' PDB 1XLW unspecified 'DIETHYLPHOSPHORYLATED BUTYRYLCHOLINESTERASE (NONAGED) OBTAINED BY REACTION WITH ECHOTHIOPHATE' PDB 1P0I unspecified 'CRYSTAL STRUCTURE OF HUMAN BUTYRYL CHOLINESTERASE' PDB 2WIG unspecified 'NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2WIL _pdbx_database_status.recvd_initial_deposition_date 2009-05-12 _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Carletti, E.' 1 'Aurbek, N.' 2 'Gillon, E.' 3 'Loiodice, M.' 4 'Nicolet, Y.' 5 'Fontecilla, J.' 6 'Masson, P.' 7 'Thiermann, H.' 8 'Nachon, F.' 9 'Worek, F.' 10 # _citation.id primary _citation.title 'Structure-Activity Analysis of Aging and Reactivation of Human Butyrylcholinesterase Inhibited by Analogues of Tabun' _citation.journal_abbrev Biochem.J. _citation.journal_volume 421 _citation.page_first 97 _citation.page_last ? _citation.year 2009 _citation.journal_id_ASTM BIJOAK _citation.country UK _citation.journal_id_ISSN 0264-6021 _citation.journal_id_CSD 0043 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 19368529 _citation.pdbx_database_id_DOI 10.1042/BJ20090091 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Carletti, E.' 1 primary 'Aurbek, N.' 2 primary 'Gillon, E.' 3 primary 'Loiodice, M.' 4 primary 'Nicolet, Y.' 5 primary 'Fontecilla, J.' 6 primary 'Masson, P.' 7 primary 'Thiermann, H.' 8 primary 'Nachon, F.' 9 primary 'Worek, F.' 10 # _cell.entry_id 2WIL _cell.length_a 150.350 _cell.length_b 150.350 _cell.length_c 139.430 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 16 _cell.pdbx_unique_axis ? # _symmetry.entry_id 2WIL _symmetry.space_group_name_H-M 'P 4 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 90 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man CHOLINESTERASE 59685.457 2 3.1.1.8 YES 'RESIDUES 29-557' 'S198 IS PHOSPHORAMIDYLATED' 2 non-polymer syn 'ethylphosphoramidic acid' 125.064 2 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 14 ? ? ? ? 4 non-polymer man ALPHA-L-FUCOSE 164.156 4 ? ? ? ? 5 non-polymer syn 'SULFATE ION' 96.063 3 ? ? ? ? 6 non-polymer syn 'CHLORIDE ION' 35.453 1 ? ? ? ? 7 water nat water 18.015 137 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'ACYLCHOLINE ACYLHYDROLASE, BUTYRYLCHOLINE ESTERASE, CHOLINE ESTERASE II, PSEUDOCHOLINESTERASE' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;EDDIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSE MWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP EAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG VNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFIC PALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNP QETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV ; _entity_poly.pdbx_seq_one_letter_code_can ;EDDIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSE MWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP EAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG VNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFIC PALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNP QETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 ASP n 1 3 ASP n 1 4 ILE n 1 5 ILE n 1 6 ILE n 1 7 ALA n 1 8 THR n 1 9 LYS n 1 10 ASN n 1 11 GLY n 1 12 LYS n 1 13 VAL n 1 14 ARG n 1 15 GLY n 1 16 MET n 1 17 GLN n 1 18 LEU n 1 19 THR n 1 20 VAL n 1 21 PHE n 1 22 GLY n 1 23 GLY n 1 24 THR n 1 25 VAL n 1 26 THR n 1 27 ALA n 1 28 PHE n 1 29 LEU n 1 30 GLY n 1 31 ILE n 1 32 PRO n 1 33 TYR n 1 34 ALA n 1 35 GLN n 1 36 PRO n 1 37 PRO n 1 38 LEU n 1 39 GLY n 1 40 ARG n 1 41 LEU n 1 42 ARG n 1 43 PHE n 1 44 LYS n 1 45 LYS n 1 46 PRO n 1 47 GLN n 1 48 SER n 1 49 LEU n 1 50 THR n 1 51 LYS n 1 52 TRP n 1 53 SER n 1 54 ASP n 1 55 ILE n 1 56 TRP n 1 57 ASN n 1 58 ALA n 1 59 THR n 1 60 LYS n 1 61 TYR n 1 62 ALA n 1 63 ASN n 1 64 SER n 1 65 CYS n 1 66 CYS n 1 67 GLN n 1 68 ASN n 1 69 ILE n 1 70 ASP n 1 71 GLN n 1 72 SER n 1 73 PHE n 1 74 PRO n 1 75 GLY n 1 76 PHE n 1 77 HIS n 1 78 GLY n 1 79 SER n 1 80 GLU n 1 81 MET n 1 82 TRP n 1 83 ASN n 1 84 PRO n 1 85 ASN n 1 86 THR n 1 87 ASP n 1 88 LEU n 1 89 SER n 1 90 GLU n 1 91 ASP n 1 92 CYS n 1 93 LEU n 1 94 TYR n 1 95 LEU n 1 96 ASN n 1 97 VAL n 1 98 TRP n 1 99 ILE n 1 100 PRO n 1 101 ALA n 1 102 PRO n 1 103 LYS n 1 104 PRO n 1 105 LYS n 1 106 ASN n 1 107 ALA n 1 108 THR n 1 109 VAL n 1 110 LEU n 1 111 ILE n 1 112 TRP n 1 113 ILE n 1 114 TYR n 1 115 GLY n 1 116 GLY n 1 117 GLY n 1 118 PHE n 1 119 GLN n 1 120 THR n 1 121 GLY n 1 122 THR n 1 123 SER n 1 124 SER n 1 125 LEU n 1 126 HIS n 1 127 VAL n 1 128 TYR n 1 129 ASP n 1 130 GLY n 1 131 LYS n 1 132 PHE n 1 133 LEU n 1 134 ALA n 1 135 ARG n 1 136 VAL n 1 137 GLU n 1 138 ARG n 1 139 VAL n 1 140 ILE n 1 141 VAL n 1 142 VAL n 1 143 SER n 1 144 MET n 1 145 ASN n 1 146 TYR n 1 147 ARG n 1 148 VAL n 1 149 GLY n 1 150 ALA n 1 151 LEU n 1 152 GLY n 1 153 PHE n 1 154 LEU n 1 155 ALA n 1 156 LEU n 1 157 PRO n 1 158 GLY n 1 159 ASN n 1 160 PRO n 1 161 GLU n 1 162 ALA n 1 163 PRO n 1 164 GLY n 1 165 ASN n 1 166 MET n 1 167 GLY n 1 168 LEU n 1 169 PHE n 1 170 ASP n 1 171 GLN n 1 172 GLN n 1 173 LEU n 1 174 ALA n 1 175 LEU n 1 176 GLN n 1 177 TRP n 1 178 VAL n 1 179 GLN n 1 180 LYS n 1 181 ASN n 1 182 ILE n 1 183 ALA n 1 184 ALA n 1 185 PHE n 1 186 GLY n 1 187 GLY n 1 188 ASN n 1 189 PRO n 1 190 LYS n 1 191 SER n 1 192 VAL n 1 193 THR n 1 194 LEU n 1 195 PHE n 1 196 GLY n 1 197 GLU n 1 198 SER n 1 199 ALA n 1 200 GLY n 1 201 ALA n 1 202 ALA n 1 203 SER n 1 204 VAL n 1 205 SER n 1 206 LEU n 1 207 HIS n 1 208 LEU n 1 209 LEU n 1 210 SER n 1 211 PRO n 1 212 GLY n 1 213 SER n 1 214 HIS n 1 215 SER n 1 216 LEU n 1 217 PHE n 1 218 THR n 1 219 ARG n 1 220 ALA n 1 221 ILE n 1 222 LEU n 1 223 GLN n 1 224 SER n 1 225 GLY n 1 226 SER n 1 227 PHE n 1 228 ASN n 1 229 ALA n 1 230 PRO n 1 231 TRP n 1 232 ALA n 1 233 VAL n 1 234 THR n 1 235 SER n 1 236 LEU n 1 237 TYR n 1 238 GLU n 1 239 ALA n 1 240 ARG n 1 241 ASN n 1 242 ARG n 1 243 THR n 1 244 LEU n 1 245 ASN n 1 246 LEU n 1 247 ALA n 1 248 LYS n 1 249 LEU n 1 250 THR n 1 251 GLY n 1 252 CYS n 1 253 SER n 1 254 ARG n 1 255 GLU n 1 256 ASN n 1 257 GLU n 1 258 THR n 1 259 GLU n 1 260 ILE n 1 261 ILE n 1 262 LYS n 1 263 CYS n 1 264 LEU n 1 265 ARG n 1 266 ASN n 1 267 LYS n 1 268 ASP n 1 269 PRO n 1 270 GLN n 1 271 GLU n 1 272 ILE n 1 273 LEU n 1 274 LEU n 1 275 ASN n 1 276 GLU n 1 277 ALA n 1 278 PHE n 1 279 VAL n 1 280 VAL n 1 281 PRO n 1 282 TYR n 1 283 GLY n 1 284 THR n 1 285 PRO n 1 286 LEU n 1 287 SER n 1 288 VAL n 1 289 ASN n 1 290 PHE n 1 291 GLY n 1 292 PRO n 1 293 THR n 1 294 VAL n 1 295 ASP n 1 296 GLY n 1 297 ASP n 1 298 PHE n 1 299 LEU n 1 300 THR n 1 301 ASP n 1 302 MET n 1 303 PRO n 1 304 ASP n 1 305 ILE n 1 306 LEU n 1 307 LEU n 1 308 GLU n 1 309 LEU n 1 310 GLY n 1 311 GLN n 1 312 PHE n 1 313 LYS n 1 314 LYS n 1 315 THR n 1 316 GLN n 1 317 ILE n 1 318 LEU n 1 319 VAL n 1 320 GLY n 1 321 VAL n 1 322 ASN n 1 323 LYS n 1 324 ASP n 1 325 GLU n 1 326 GLY n 1 327 THR n 1 328 ALA n 1 329 PHE n 1 330 LEU n 1 331 VAL n 1 332 TYR n 1 333 GLY n 1 334 ALA n 1 335 PRO n 1 336 GLY n 1 337 PHE n 1 338 SER n 1 339 LYS n 1 340 ASP n 1 341 ASN n 1 342 ASN n 1 343 SER n 1 344 ILE n 1 345 ILE n 1 346 THR n 1 347 ARG n 1 348 LYS n 1 349 GLU n 1 350 PHE n 1 351 GLN n 1 352 GLU n 1 353 GLY n 1 354 LEU n 1 355 LYS n 1 356 ILE n 1 357 PHE n 1 358 PHE n 1 359 PRO n 1 360 GLY n 1 361 VAL n 1 362 SER n 1 363 GLU n 1 364 PHE n 1 365 GLY n 1 366 LYS n 1 367 GLU n 1 368 SER n 1 369 ILE n 1 370 LEU n 1 371 PHE n 1 372 HIS n 1 373 TYR n 1 374 THR n 1 375 ASP n 1 376 TRP n 1 377 VAL n 1 378 ASP n 1 379 ASP n 1 380 GLN n 1 381 ARG n 1 382 PRO n 1 383 GLU n 1 384 ASN n 1 385 TYR n 1 386 ARG n 1 387 GLU n 1 388 ALA n 1 389 LEU n 1 390 GLY n 1 391 ASP n 1 392 VAL n 1 393 VAL n 1 394 GLY n 1 395 ASP n 1 396 TYR n 1 397 ASN n 1 398 PHE n 1 399 ILE n 1 400 CYS n 1 401 PRO n 1 402 ALA n 1 403 LEU n 1 404 GLU n 1 405 PHE n 1 406 THR n 1 407 LYS n 1 408 LYS n 1 409 PHE n 1 410 SER n 1 411 GLU n 1 412 TRP n 1 413 GLY n 1 414 ASN n 1 415 ASN n 1 416 ALA n 1 417 PHE n 1 418 PHE n 1 419 TYR n 1 420 TYR n 1 421 PHE n 1 422 GLU n 1 423 HIS n 1 424 ARG n 1 425 SER n 1 426 SER n 1 427 LYS n 1 428 LEU n 1 429 PRO n 1 430 TRP n 1 431 PRO n 1 432 GLU n 1 433 TRP n 1 434 MET n 1 435 GLY n 1 436 VAL n 1 437 MET n 1 438 HIS n 1 439 GLY n 1 440 TYR n 1 441 GLU n 1 442 ILE n 1 443 GLU n 1 444 PHE n 1 445 VAL n 1 446 PHE n 1 447 GLY n 1 448 LEU n 1 449 PRO n 1 450 LEU n 1 451 GLU n 1 452 ARG n 1 453 ARG n 1 454 ASP n 1 455 ASN n 1 456 TYR n 1 457 THR n 1 458 LYS n 1 459 ALA n 1 460 GLU n 1 461 GLU n 1 462 ILE n 1 463 LEU n 1 464 SER n 1 465 ARG n 1 466 SER n 1 467 ILE n 1 468 VAL n 1 469 LYS n 1 470 ARG n 1 471 TRP n 1 472 ALA n 1 473 ASN n 1 474 PHE n 1 475 ALA n 1 476 LYS n 1 477 TYR n 1 478 GLY n 1 479 ASN n 1 480 PRO n 1 481 GLN n 1 482 GLU n 1 483 THR n 1 484 GLN n 1 485 ASN n 1 486 ASN n 1 487 SER n 1 488 THR n 1 489 SER n 1 490 TRP n 1 491 PRO n 1 492 VAL n 1 493 PHE n 1 494 LYS n 1 495 SER n 1 496 THR n 1 497 GLU n 1 498 GLN n 1 499 LYS n 1 500 TYR n 1 501 LEU n 1 502 THR n 1 503 LEU n 1 504 ASN n 1 505 THR n 1 506 GLU n 1 507 SER n 1 508 THR n 1 509 ARG n 1 510 ILE n 1 511 MET n 1 512 THR n 1 513 LYS n 1 514 LEU n 1 515 ARG n 1 516 ALA n 1 517 GLN n 1 518 GLN n 1 519 CYS n 1 520 ARG n 1 521 PHE n 1 522 TRP n 1 523 THR n 1 524 SER n 1 525 PHE n 1 526 PHE n 1 527 PRO n 1 528 LYS n 1 529 VAL n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Cricetulus griseus' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 10029 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant K1 _entity_src_gen.pdbx_host_org_cell_line CHO _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type PLASMID _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name PGS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code CHLE_HUMAN _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession P06276 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2WIL A 1 ? 529 ? P06276 29 ? 557 ? 1 529 2 1 2WIL B 1 ? 529 ? P06276 29 ? 557 ? 1 529 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2WIL GLN A 17 ? UNP P06276 ASN 45 'engineered mutation' 17 1 1 2WIL GLN A 481 ? UNP P06276 ASN 509 'engineered mutation' 481 2 2 2WIL GLN B 17 ? UNP P06276 ASN 45 'engineered mutation' 17 3 2 2WIL GLN B 481 ? UNP P06276 ASN 509 'engineered mutation' 481 4 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 TCX non-polymer . 'ethylphosphoramidic acid' ? 'C2 H8 N O3 P' 125.064 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 2WIL _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.3 _exptl_crystal.density_percent_sol 62.7 _exptl_crystal.description NONE # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '2.1 M AMMONIUM SULFATE, 100 MM MES PH 6.5, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 293K' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC CCD' _diffrn_detector.pdbx_collection_date 2008-09-05 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9395 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID14-4' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID14-4 _diffrn_source.pdbx_wavelength 0.9395 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 2WIL _reflns.observed_criterion_sigma_I 2.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 48.40 _reflns.d_resolution_high 3.10 _reflns.number_obs 28167 _reflns.number_all ? _reflns.percent_possible_obs 98.2 _reflns.pdbx_Rmerge_I_obs 0.10 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 29.20 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 5.7 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 3.10 _reflns_shell.d_res_low 3.20 _reflns_shell.percent_possible_all 98.2 _reflns_shell.Rmerge_I_obs 0.30 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 8.60 _reflns_shell.pdbx_redundancy 5.9 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 2WIL _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 28167 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F . _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 48.39 _refine.ls_d_res_high 3.10 _refine.ls_percent_reflns_obs 98.25 _refine.ls_R_factor_obs 0.22120 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.22016 _refine.ls_R_factor_R_free 0.25281 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 3.2 _refine.ls_number_reflns_R_free 937 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.931 _refine.correlation_coeff_Fo_to_Fc_free 0.913 _refine.B_iso_mean 73.731 _refine.aniso_B[1][1] -0.02 _refine.aniso_B[2][2] -0.02 _refine.aniso_B[3][3] 0.05 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'BABINET MODEL WITH MASK' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.' _refine.pdbx_starting_model 'PDB ENTRY 1P0I' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free 0.445 _refine.overall_SU_ML 0.336 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 19.693 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8364 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 264 _refine_hist.number_atoms_solvent 137 _refine_hist.number_atoms_total 8765 _refine_hist.d_res_high 3.10 _refine_hist.d_res_low 48.39 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.012 0.022 ? 8916 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.415 1.976 ? 12142 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 5.988 5.000 ? 1056 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 35.627 24.020 ? 403 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 19.034 15.000 ? 1400 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 17.531 15.000 ? 44 'X-RAY DIFFRACTION' ? r_chiral_restr 0.087 0.200 ? 1327 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.005 0.021 ? 6734 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.598 1.500 ? 5247 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.146 2.000 ? 8475 'X-RAY DIFFRACTION' ? r_mcangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_it 1.358 3.000 ? 3669 'X-RAY DIFFRACTION' ? r_scbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_it 2.480 4.500 ? 3664 'X-RAY DIFFRACTION' ? r_scangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_restr_ncs.dom_id _refine_ls_restr_ncs.pdbx_auth_asym_id _refine_ls_restr_ncs.pdbx_number _refine_ls_restr_ncs.rms_dev_position _refine_ls_restr_ncs.weight_position _refine_ls_restr_ncs.pdbx_type _refine_ls_restr_ncs.pdbx_ens_id _refine_ls_restr_ncs.pdbx_ordinal _refine_ls_restr_ncs.pdbx_refine_id _refine_ls_restr_ncs.ncs_model_details _refine_ls_restr_ncs.rms_dev_B_iso _refine_ls_restr_ncs.weight_B_iso 1 A 118 0.03 0.05 'tight positional' 1 1 'X-RAY DIFFRACTION' ? ? ? 2 B 118 0.03 0.05 'tight positional' 1 2 'X-RAY DIFFRACTION' ? ? ? 1 A 4185 0.04 0.05 'tight positional' 2 3 'X-RAY DIFFRACTION' ? ? ? 2 B 4185 0.04 0.05 'tight positional' 2 4 'X-RAY DIFFRACTION' ? ? ? 1 A 118 0.35 0.50 'tight thermal' 1 5 'X-RAY DIFFRACTION' ? ? ? 2 B 118 0.35 0.50 'tight thermal' 1 6 'X-RAY DIFFRACTION' ? ? ? 1 A 4185 0.11 0.50 'tight thermal' 2 7 'X-RAY DIFFRACTION' ? ? ? 2 B 4185 0.11 0.50 'tight thermal' 2 8 'X-RAY DIFFRACTION' ? ? ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 3.100 _refine_ls_shell.d_res_low 3.180 _refine_ls_shell.number_reflns_R_work 2026 _refine_ls_shell.R_factor_R_work 0.352 _refine_ls_shell.percent_reflns_obs 98.08 _refine_ls_shell.R_factor_R_free 0.416 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 64 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # loop_ _struct_ncs_dom.id _struct_ncs_dom.details _struct_ncs_dom.pdbx_ens_id 1 A 1 2 B 1 1 A 2 2 B 2 # loop_ _struct_ncs_dom_lim.dom_id _struct_ncs_dom_lim.beg_auth_asym_id _struct_ncs_dom_lim.beg_auth_seq_id _struct_ncs_dom_lim.end_auth_asym_id _struct_ncs_dom_lim.end_auth_seq_id _struct_ncs_dom_lim.pdbx_component_id _struct_ncs_dom_lim.pdbx_refine_code _struct_ncs_dom_lim.beg_label_asym_id _struct_ncs_dom_lim.beg_label_comp_id _struct_ncs_dom_lim.beg_label_seq_id _struct_ncs_dom_lim.beg_label_alt_id _struct_ncs_dom_lim.end_label_asym_id _struct_ncs_dom_lim.end_label_comp_id _struct_ncs_dom_lim.end_label_seq_id _struct_ncs_dom_lim.end_label_alt_id _struct_ncs_dom_lim.pdbx_ens_id _struct_ncs_dom_lim.selection_details 1 A 1531 A 1542 1 1 ? ? ? ? ? ? ? ? 1 ? 2 B 1531 B 1539 1 1 ? ? ? ? ? ? ? ? 1 ? 1 A 2 A 529 1 1 ? ? ? ? ? ? ? ? 2 ? 2 B 4 B 529 1 1 ? ? ? ? ? ? ? ? 2 ? # loop_ _struct_ncs_ens.id _struct_ncs_ens.details 1 ? 2 ? # _struct.entry_id 2WIL _struct.title 'AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5' _struct.pdbx_descriptor 'CHOLINESTERASE (E.C.3.1.1.8)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2WIL _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'AGING, HYDROLASE, INHIBITION, POLYMORPHISM, GLYCOPROTEIN, SERINE ESTERASE, DISEASE MUTATION' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 4 ? G N N 3 ? H N N 3 ? I N N 4 ? J N N 3 ? K N N 3 ? L N N 3 ? M N N 5 ? N N N 5 ? O N N 6 ? P N N 2 ? Q N N 3 ? R N N 3 ? S N N 4 ? T N N 3 ? U N N 3 ? V N N 4 ? W N N 3 ? X N N 3 ? Y N N 3 ? Z N N 5 ? AA N N 7 ? BA N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 LEU A 38 ? ARG A 42 ? LEU A 38 ARG A 42 5 ? 5 HELX_P HELX_P2 AA2 PHE A 76 ? MET A 81 ? PHE A 76 MET A 81 1 ? 6 HELX_P HELX_P3 AA3 LEU A 125 ? ASP A 129 ? LEU A 125 ASP A 129 5 ? 5 HELX_P HELX_P4 AA4 GLY A 130 ? ARG A 138 ? GLY A 130 ARG A 138 1 ? 9 HELX_P HELX_P5 AA5 VAL A 148 ? LEU A 154 ? VAL A 148 LEU A 154 1 ? 7 HELX_P HELX_P6 AA6 ASN A 165 ? ILE A 182 ? ASN A 165 ILE A 182 1 ? 18 HELX_P HELX_P7 AA7 ALA A 183 ? PHE A 185 ? ALA A 183 PHE A 185 5 ? 3 HELX_P HELX_P8 AA8 SER A 198 ? SER A 210 ? SER A 198 SER A 210 1 ? 13 HELX_P HELX_P9 AA9 SER A 210 ? SER A 215 ? SER A 210 SER A 215 1 ? 6 HELX_P HELX_P10 AB1 SER A 235 ? THR A 250 ? SER A 235 THR A 250 1 ? 16 HELX_P HELX_P11 AB2 ASN A 256 ? ARG A 265 ? ASN A 256 ARG A 265 1 ? 10 HELX_P HELX_P12 AB3 ASP A 268 ? ALA A 277 ? ASP A 268 ALA A 277 1 ? 10 HELX_P HELX_P13 AB4 MET A 302 ? LEU A 309 ? MET A 302 LEU A 309 1 ? 8 HELX_P HELX_P14 AB5 GLY A 326 ? VAL A 331 ? GLY A 326 VAL A 331 1 ? 6 HELX_P HELX_P15 AB6 THR A 346 ? PHE A 358 ? THR A 346 PHE A 358 1 ? 13 HELX_P HELX_P16 AB7 SER A 362 ? THR A 374 ? SER A 362 THR A 374 1 ? 13 HELX_P HELX_P17 AB8 GLU A 383 ? PHE A 398 ? GLU A 383 PHE A 398 1 ? 16 HELX_P HELX_P18 AB9 PHE A 398 ? GLU A 411 ? PHE A 398 GLU A 411 1 ? 14 HELX_P HELX_P19 AC1 PRO A 431 ? GLY A 435 ? PRO A 431 GLY A 435 5 ? 5 HELX_P HELX_P20 AC2 GLU A 441 ? PHE A 446 ? GLU A 441 PHE A 446 1 ? 6 HELX_P HELX_P21 AC3 GLY A 447 ? GLU A 451 ? GLY A 447 GLU A 451 5 ? 5 HELX_P HELX_P22 AC4 THR A 457 ? GLY A 478 ? THR A 457 GLY A 478 1 ? 22 HELX_P HELX_P23 AC5 ARG A 515 ? SER A 524 ? ARG A 515 SER A 524 1 ? 10 HELX_P HELX_P24 AC6 PHE A 525 ? VAL A 529 ? PHE A 525 VAL A 529 5 ? 5 HELX_P HELX_P25 AC7 LEU B 38 ? ARG B 42 ? LEU B 38 ARG B 42 5 ? 5 HELX_P HELX_P26 AC8 PHE B 76 ? MET B 81 ? PHE B 76 MET B 81 1 ? 6 HELX_P HELX_P27 AC9 LEU B 125 ? ASP B 129 ? LEU B 125 ASP B 129 5 ? 5 HELX_P HELX_P28 AD1 GLY B 130 ? ARG B 138 ? GLY B 130 ARG B 138 1 ? 9 HELX_P HELX_P29 AD2 VAL B 148 ? LEU B 154 ? VAL B 148 LEU B 154 1 ? 7 HELX_P HELX_P30 AD3 ASN B 165 ? ILE B 182 ? ASN B 165 ILE B 182 1 ? 18 HELX_P HELX_P31 AD4 ALA B 183 ? PHE B 185 ? ALA B 183 PHE B 185 5 ? 3 HELX_P HELX_P32 AD5 SER B 198 ? SER B 210 ? SER B 198 SER B 210 1 ? 13 HELX_P HELX_P33 AD6 PRO B 211 ? PHE B 217 ? PRO B 211 PHE B 217 5 ? 7 HELX_P HELX_P34 AD7 SER B 235 ? THR B 250 ? SER B 235 THR B 250 1 ? 16 HELX_P HELX_P35 AD8 ASN B 256 ? ARG B 265 ? ASN B 256 ARG B 265 1 ? 10 HELX_P HELX_P36 AD9 ASP B 268 ? ALA B 277 ? ASP B 268 ALA B 277 1 ? 10 HELX_P HELX_P37 AE1 MET B 302 ? LEU B 309 ? MET B 302 LEU B 309 1 ? 8 HELX_P HELX_P38 AE2 GLY B 326 ? VAL B 331 ? GLY B 326 VAL B 331 1 ? 6 HELX_P HELX_P39 AE3 THR B 346 ? PHE B 358 ? THR B 346 PHE B 358 1 ? 13 HELX_P HELX_P40 AE4 SER B 362 ? THR B 374 ? SER B 362 THR B 374 1 ? 13 HELX_P HELX_P41 AE5 GLU B 383 ? PHE B 398 ? GLU B 383 PHE B 398 1 ? 16 HELX_P HELX_P42 AE6 PHE B 398 ? GLU B 411 ? PHE B 398 GLU B 411 1 ? 14 HELX_P HELX_P43 AE7 PRO B 431 ? GLY B 435 ? PRO B 431 GLY B 435 5 ? 5 HELX_P HELX_P44 AE8 GLU B 441 ? PHE B 446 ? GLU B 441 PHE B 446 1 ? 6 HELX_P HELX_P45 AE9 GLY B 447 ? GLU B 451 ? GLY B 447 GLU B 451 5 ? 5 HELX_P HELX_P46 AF1 THR B 457 ? GLY B 478 ? THR B 457 GLY B 478 1 ? 22 HELX_P HELX_P47 AF2 ARG B 515 ? PHE B 525 ? ARG B 515 PHE B 525 1 ? 11 HELX_P HELX_P48 AF3 PHE B 526 ? VAL B 529 ? PHE B 526 VAL B 529 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 65 SG ? ? ? 1_555 A CYS 92 SG ? ? A CYS 65 A CYS 92 1_555 ? ? ? ? ? ? ? 2.018 ? disulf2 disulf ? ? A CYS 252 SG ? ? ? 1_555 A CYS 263 SG ? ? A CYS 252 A CYS 263 1_555 ? ? ? ? ? ? ? 2.036 ? disulf3 disulf ? ? A CYS 400 SG ? ? ? 1_555 A CYS 519 SG ? ? A CYS 400 A CYS 519 1_555 ? ? ? ? ? ? ? 2.055 ? disulf4 disulf ? ? B CYS 65 SG ? ? ? 1_555 B CYS 92 SG ? ? B CYS 65 B CYS 92 1_555 ? ? ? ? ? ? ? 2.049 ? disulf5 disulf ? ? B CYS 252 SG ? ? ? 1_555 B CYS 263 SG ? ? B CYS 252 B CYS 263 1_555 ? ? ? ? ? ? ? 2.038 ? disulf6 disulf ? ? B CYS 400 SG ? ? ? 1_555 B CYS 519 SG ? ? B CYS 400 B CYS 519 1_555 ? ? ? ? ? ? ? 2.055 ? covale1 covale one ? A ASN 57 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 57 A NAG 609 1_555 ? ? ? ? ? ? ? 1.478 ? covale2 covale one ? A ASN 106 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 106 A NAG 608 1_555 ? ? ? ? ? ? ? 1.464 ? covale3 covale one ? A SER 198 OG ? ? ? 1_555 C TCX . P ? ? A SER 198 A TCX 601 1_555 ? ? ? ? ? ? ? 1.606 ? covale4 covale one ? A ASN 241 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 241 A NAG 602 1_555 ? ? ? ? ? ? ? 1.461 ? covale5 covale one ? A ASN 341 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 341 A NAG 605 1_555 ? ? ? ? ? ? ? 1.440 ? covale6 covale one ? A ASN 485 ND2 ? ? ? 1_555 L NAG . C1 ? ? A ASN 485 A NAG 610 1_555 ? ? ? ? ? ? ? 1.448 ? covale7 covale one ? B ASN 57 ND2 ? ? ? 1_555 X NAG . C1 ? ? B ASN 57 B NAG 609 1_555 ? ? ? ? ? ? ? 1.470 ? covale8 covale one ? B ASN 106 ND2 ? ? ? 1_555 W NAG . C1 ? ? B ASN 106 B NAG 608 1_555 ? ? ? ? ? ? ? 1.453 ? covale9 covale one ? B SER 198 OG ? ? ? 1_555 P TCX . P ? ? B SER 198 B TCX 601 1_555 ? ? ? ? ? ? ? 1.612 ? covale10 covale one ? B ASN 241 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 241 B NAG 602 1_555 ? ? ? ? ? ? ? 1.455 ? covale11 covale one ? B ASN 341 ND2 ? ? ? 1_555 T NAG . C1 ? ? B ASN 341 B NAG 605 1_555 ? ? ? ? ? ? ? 1.456 ? covale12 covale one ? B ASN 485 ND2 ? ? ? 1_555 Y NAG . C1 ? ? B ASN 485 B NAG 610 1_555 ? ? ? ? ? ? ? 1.447 ? covale13 covale both ? D NAG . O4 ? ? ? 1_555 E NAG . C1 ? ? A NAG 602 A NAG 603 1_555 ? ? ? ? ? ? ? 1.464 ? covale14 covale one ? D NAG . O6 ? ? ? 1_555 F FUC . C1 ? ? A NAG 602 A FUC 604 1_555 ? ? ? ? ? ? ? 1.459 ? covale15 covale both ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? A NAG 605 A NAG 606 1_555 ? ? ? ? ? ? ? 1.446 ? covale16 covale one ? G NAG . O6 ? ? ? 1_555 I FUC . C1 ? ? A NAG 605 A FUC 607 1_555 ? ? ? ? ? ? ? 1.448 ? covale17 covale both ? Q NAG . O4 ? ? ? 1_555 R NAG . C1 ? ? B NAG 602 B NAG 603 1_555 ? ? ? ? ? ? ? 1.458 ? covale18 covale one ? Q NAG . O6 ? ? ? 1_555 S FUC . C1 ? ? B NAG 602 B FUC 604 1_555 ? ? ? ? ? ? ? 1.449 ? covale19 covale both ? T NAG . O4 ? ? ? 1_555 U NAG . C1 ? ? B NAG 605 B NAG 606 1_555 ? ? ? ? ? ? ? 1.453 ? covale20 covale one ? T NAG . O6 ? ? ? 1_555 V FUC . C1 ? ? B NAG 605 B FUC 607 1_555 ? ? ? ? ? ? ? 1.445 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASP 2 A . ? ASP 2 A ASP 3 A ? ASP 3 A 1 11.34 2 ALA 101 A . ? ALA 101 A PRO 102 A ? PRO 102 A 1 9.15 3 ALA 101 B . ? ALA 101 B PRO 102 B ? PRO 102 B 1 9.03 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 3 ? AA2 ? 11 ? AA3 ? 3 ? AA4 ? 11 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? parallel AA2 5 6 ? parallel AA2 6 7 ? parallel AA2 7 8 ? parallel AA2 8 9 ? parallel AA2 9 10 ? parallel AA2 10 11 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA4 4 5 ? parallel AA4 5 6 ? parallel AA4 6 7 ? parallel AA4 7 8 ? parallel AA4 8 9 ? parallel AA4 9 10 ? parallel AA4 10 11 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 ILE A 5 ? THR A 8 ? ILE A 5 THR A 8 AA1 2 GLY A 11 ? ARG A 14 ? GLY A 11 ARG A 14 AA1 3 ILE A 55 ? ASN A 57 ? ILE A 55 ASN A 57 AA2 1 GLN A 17 ? THR A 19 ? GLN A 17 THR A 19 AA2 2 THR A 24 ? PRO A 32 ? THR A 24 PRO A 32 AA2 3 TYR A 94 ? PRO A 100 ? TYR A 94 PRO A 100 AA2 4 ILE A 140 ? MET A 144 ? ILE A 140 MET A 144 AA2 5 ALA A 107 ? ILE A 113 ? ALA A 107 ILE A 113 AA2 6 GLY A 187 ? GLU A 197 ? GLY A 187 GLU A 197 AA2 7 ARG A 219 ? GLN A 223 ? ARG A 219 GLN A 223 AA2 8 ILE A 317 ? ASN A 322 ? ILE A 317 ASN A 322 AA2 9 ALA A 416 ? PHE A 421 ? ALA A 416 PHE A 421 AA2 10 LYS A 499 ? LEU A 503 ? LYS A 499 LEU A 503 AA2 11 ILE A 510 ? THR A 512 ? ILE A 510 THR A 512 AA3 1 ILE B 5 ? THR B 8 ? ILE B 5 THR B 8 AA3 2 GLY B 11 ? ARG B 14 ? GLY B 11 ARG B 14 AA3 3 ILE B 55 ? ASN B 57 ? ILE B 55 ASN B 57 AA4 1 GLN B 17 ? THR B 19 ? GLN B 17 THR B 19 AA4 2 THR B 24 ? PRO B 32 ? THR B 24 PRO B 32 AA4 3 TYR B 94 ? ALA B 101 ? TYR B 94 ALA B 101 AA4 4 ILE B 140 ? MET B 144 ? ILE B 140 MET B 144 AA4 5 ALA B 107 ? ILE B 113 ? ALA B 107 ILE B 113 AA4 6 GLY B 187 ? GLU B 197 ? GLY B 187 GLU B 197 AA4 7 ARG B 219 ? GLN B 223 ? ARG B 219 GLN B 223 AA4 8 ILE B 317 ? ASN B 322 ? ILE B 317 ASN B 322 AA4 9 ALA B 416 ? PHE B 421 ? ALA B 416 PHE B 421 AA4 10 LYS B 499 ? LEU B 503 ? LYS B 499 LEU B 503 AA4 11 ILE B 510 ? THR B 512 ? ILE B 510 THR B 512 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N ILE A 6 ? N ILE A 6 O VAL A 13 ? O VAL A 13 AA1 2 3 N ARG A 14 ? N ARG A 14 O TRP A 56 ? O TRP A 56 AA2 1 2 N LEU A 18 ? N LEU A 18 O VAL A 25 ? O VAL A 25 AA2 2 3 N PHE A 28 ? N PHE A 28 O VAL A 97 ? O VAL A 97 AA2 3 4 N ASN A 96 ? N ASN A 96 O SER A 143 ? O SER A 143 AA2 4 5 O VAL A 142 ? O VAL A 142 N LEU A 110 ? N LEU A 110 AA2 5 6 N ALA A 107 ? N ALA A 107 O ASN A 188 ? O ASN A 188 AA2 6 7 N LEU A 194 ? N LEU A 194 O ARG A 219 ? O ARG A 219 AA2 7 8 N LEU A 222 ? N LEU A 222 O LEU A 318 ? O LEU A 318 AA2 8 9 N VAL A 321 ? N VAL A 321 O PHE A 421 ? O PHE A 421 AA2 9 10 N PHE A 418 ? N PHE A 418 O LEU A 501 ? O LEU A 501 AA2 10 11 N TYR A 500 ? N TYR A 500 O MET A 511 ? O MET A 511 AA3 1 2 N THR B 8 ? N THR B 8 O GLY B 11 ? O GLY B 11 AA3 2 3 N LYS B 12 ? N LYS B 12 O TRP B 56 ? O TRP B 56 AA4 1 2 N LEU B 18 ? N LEU B 18 O VAL B 25 ? O VAL B 25 AA4 2 3 N PHE B 28 ? N PHE B 28 O VAL B 97 ? O VAL B 97 AA4 3 4 N ASN B 96 ? N ASN B 96 O SER B 143 ? O SER B 143 AA4 4 5 O VAL B 142 ? O VAL B 142 N LEU B 110 ? N LEU B 110 AA4 5 6 N ALA B 107 ? N ALA B 107 O ASN B 188 ? O ASN B 188 AA4 6 7 N LEU B 194 ? N LEU B 194 O ARG B 219 ? O ARG B 219 AA4 7 8 N LEU B 222 ? N LEU B 222 O LEU B 318 ? O LEU B 318 AA4 8 9 N VAL B 319 ? N VAL B 319 O PHE B 417 ? O PHE B 417 AA4 9 10 N PHE B 418 ? N PHE B 418 O LEU B 501 ? O LEU B 501 AA4 10 11 N TYR B 500 ? N TYR B 500 O MET B 511 ? O MET B 511 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE TCX A 600' AC2 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE TCX B 600' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A1537' AC4 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A1538' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A1539' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG B1537' AC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG B1538' AC8 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B1539' AC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 A1540' BC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 A1541' BC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 B1540' BC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE CL A1542' BC4 Software ? ? ? ? 5 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 241 RESIDUES 1531 TO 1533' BC5 Software ? ? ? ? 5 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 341 RESIDUES 1534 TO 1536' BC6 Software ? ? ? ? 5 'BINDING SITE FOR CHAIN B OF SUGAR BOUND TO ASN B 241 RESIDUES 1531 TO 1533' BC7 Software ? ? ? ? 2 'BINDING SITE FOR CHAIN B OF SUGAR BOUND TO ASN B 341 RESIDUES 1534 TO 1536' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 7 GLY A 116 ? GLY A 116 . ? 1_555 ? 2 AC1 7 GLY A 117 ? GLY A 117 . ? 1_555 ? 3 AC1 7 SER A 198 ? SER A 198 . ? 1_555 ? 4 AC1 7 ALA A 199 ? ALA A 199 . ? 1_555 ? 5 AC1 7 TRP A 231 ? TRP A 231 . ? 1_555 ? 6 AC1 7 LEU A 286 ? LEU A 286 . ? 1_555 ? 7 AC1 7 HIS A 438 ? HIS A 438 . ? 1_555 ? 8 AC2 8 GLY B 116 ? GLY B 116 . ? 1_555 ? 9 AC2 8 GLY B 117 ? GLY B 117 . ? 1_555 ? 10 AC2 8 SER B 198 ? SER B 198 . ? 1_555 ? 11 AC2 8 ALA B 199 ? ALA B 199 . ? 1_555 ? 12 AC2 8 TRP B 231 ? TRP B 231 . ? 1_555 ? 13 AC2 8 LEU B 286 ? LEU B 286 . ? 1_555 ? 14 AC2 8 PHE B 398 ? PHE B 398 . ? 1_555 ? 15 AC2 8 HIS B 438 ? HIS B 438 . ? 1_555 ? 16 AC3 3 ASN A 106 ? ASN A 106 . ? 1_555 ? 17 AC3 3 ASN A 188 ? ASN A 188 . ? 1_555 ? 18 AC3 3 HOH AA . ? HOH A 727 . ? 1_555 ? 19 AC4 3 ARG A 14 ? ARG A 14 . ? 1_555 ? 20 AC4 3 ASN A 57 ? ASN A 57 . ? 1_555 ? 21 AC4 3 HOH AA . ? HOH A 715 . ? 1_555 ? 22 AC5 3 ARG A 465 ? ARG A 465 . ? 1_555 ? 23 AC5 3 GLU A 482 ? GLU A 482 . ? 1_555 ? 24 AC5 3 ASN A 485 ? ASN A 485 . ? 1_555 ? 25 AC6 3 ASN B 106 ? ASN B 106 . ? 1_555 ? 26 AC6 3 ASN B 188 ? ASN B 188 . ? 1_555 ? 27 AC6 3 HOH BA . ? HOH B 742 . ? 1_555 ? 28 AC7 2 ARG B 14 ? ARG B 14 . ? 1_555 ? 29 AC7 2 ASN B 57 ? ASN B 57 . ? 1_555 ? 30 AC8 4 ARG B 465 ? ARG B 465 . ? 1_555 ? 31 AC8 4 GLU B 482 ? GLU B 482 . ? 1_555 ? 32 AC8 4 ASN B 485 ? ASN B 485 . ? 1_555 ? 33 AC8 4 HOH BA . ? HOH B 755 . ? 1_555 ? 34 AC9 3 GLN A 316 ? GLN A 316 . ? 1_555 ? 35 AC9 3 ASN A 414 ? ASN A 414 . ? 1_555 ? 36 AC9 3 ASN A 415 ? ASN A 415 . ? 1_555 ? 37 BC1 4 LEU A 514 ? LEU A 514 . ? 1_555 ? 38 BC1 4 ARG A 515 ? ARG A 515 . ? 1_555 ? 39 BC1 4 GLN A 518 ? GLN A 518 . ? 1_555 ? 40 BC1 4 ARG B 509 ? ARG B 509 . ? 1_555 ? 41 BC2 3 GLN B 316 ? GLN B 316 . ? 1_555 ? 42 BC2 3 ASN B 414 ? ASN B 414 . ? 1_555 ? 43 BC2 3 ASN B 415 ? ASN B 415 . ? 1_555 ? 44 BC3 1 TYR A 420 ? TYR A 420 . ? 1_555 ? 45 BC4 5 TYR A 237 ? TYR A 237 . ? 1_555 ? 46 BC4 5 ASN A 241 ? ASN A 241 . ? 1_555 ? 47 BC4 5 ASN A 245 ? ASN A 245 . ? 1_555 ? 48 BC4 5 PHE A 278 ? PHE A 278 . ? 1_555 ? 49 BC4 5 HOH AA . ? HOH A 744 . ? 1_555 ? 50 BC5 5 SER A 338 ? SER A 338 . ? 1_555 ? 51 BC5 5 ASN A 341 ? ASN A 341 . ? 1_555 ? 52 BC5 5 HOH AA . ? HOH A 748 . ? 1_555 ? 53 BC5 5 HOH AA . ? HOH A 740 . ? 1_555 ? 54 BC5 5 HOH AA . ? HOH A 724 . ? 1_555 ? 55 BC6 5 TYR B 237 ? TYR B 237 . ? 1_555 ? 56 BC6 5 ASN B 241 ? ASN B 241 . ? 1_555 ? 57 BC6 5 ASN B 245 ? ASN B 245 . ? 1_555 ? 58 BC6 5 PHE B 278 ? PHE B 278 . ? 1_555 ? 59 BC6 5 HOH BA . ? HOH B 736 . ? 1_555 ? 60 BC7 2 SER B 338 ? SER B 338 . ? 1_555 ? 61 BC7 2 ASN B 341 ? ASN B 341 . ? 1_555 ? # _database_PDB_matrix.entry_id 2WIL _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2WIL _atom_sites.fract_transf_matrix[1][1] 0.006651 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006651 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007172 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 2 ? -54.891 -36.749 -18.555 1.00 96.75 ? 2 ASP A N 1 ATOM 2 C CA . ASP A 1 2 ? -54.491 -35.957 -17.349 1.00 97.04 ? 2 ASP A CA 1 ATOM 3 C C . ASP A 1 2 ? -53.012 -36.195 -16.972 1.00 96.76 ? 2 ASP A C 1 ATOM 4 O O . ASP A 1 2 ? -52.729 -36.948 -16.022 1.00 96.77 ? 2 ASP A O 1 ATOM 5 C CB . ASP A 1 2 ? -55.388 -36.310 -16.149 1.00 97.32 ? 2 ASP A CB 1 ATOM 6 C CG . ASP A 1 2 ? -54.865 -37.518 -15.357 1.00 98.05 ? 2 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 2 ? -54.963 -37.513 -14.106 1.00 98.60 ? 2 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 2 ? -54.337 -38.464 -15.989 1.00 98.31 ? 2 ASP A OD2 1 ATOM 9 N N . ASP A 1 3 ? -52.069 -35.533 -17.658 1.00 96.15 ? 3 ASP A N 1 ATOM 10 C CA . ASP A 1 3 ? -52.321 -34.415 -18.589 1.00 95.23 ? 3 ASP A CA 1 ATOM 11 C C . ASP A 1 3 ? -53.433 -33.515 -18.080 1.00 93.95 ? 3 ASP A C 1 ATOM 12 O O . ASP A 1 3 ? -54.625 -33.848 -18.142 1.00 93.92 ? 3 ASP A O 1 ATOM 13 C CB . ASP A 1 3 ? -52.599 -34.877 -20.033 1.00 95.69 ? 3 ASP A CB 1 ATOM 14 C CG . ASP A 1 3 ? -52.057 -33.891 -21.090 1.00 96.90 ? 3 ASP A CG 1 ATOM 15 O OD1 . ASP A 1 3 ? -51.689 -34.355 -22.189 1.00 99.72 ? 3 ASP A OD1 1 ATOM 16 O OD2 . ASP A 1 3 ? -51.981 -32.668 -20.842 1.00 96.90 ? 3 ASP A OD2 1 ATOM 17 N N . ILE A 1 4 ? -53.038 -32.364 -17.575 1.00 91.77 ? 4 ILE A N 1 ATOM 18 C CA . ILE A 1 4 ? -54.026 -31.518 -16.977 1.00 90.58 ? 4 ILE A CA 1 ATOM 19 C C . ILE A 1 4 ? -53.683 -30.050 -17.210 1.00 89.68 ? 4 ILE A C 1 ATOM 20 O O . ILE A 1 4 ? -52.718 -29.516 -16.665 1.00 89.71 ? 4 ILE A O 1 ATOM 21 C CB . ILE A 1 4 ? -54.206 -31.919 -15.500 1.00 90.69 ? 4 ILE A CB 1 ATOM 22 C CG1 . ILE A 1 4 ? -55.603 -31.552 -14.974 1.00 91.08 ? 4 ILE A CG1 1 ATOM 23 C CG2 . ILE A 1 4 ? -53.072 -31.406 -14.654 1.00 90.23 ? 4 ILE A CG2 1 ATOM 24 C CD1 . ILE A 1 4 ? -56.027 -32.403 -13.764 1.00 92.17 ? 4 ILE A CD1 1 ATOM 25 N N . ILE A 1 5 ? -54.486 -29.413 -18.053 1.00 88.44 ? 5 ILE A N 1 ATOM 26 C CA . ILE A 1 5 ? -54.189 -28.081 -18.533 1.00 87.26 ? 5 ILE A CA 1 ATOM 27 C C . ILE A 1 5 ? -55.181 -27.065 -18.009 1.00 86.87 ? 5 ILE A C 1 ATOM 28 O O . ILE A 1 5 ? -56.381 -27.323 -18.019 1.00 86.65 ? 5 ILE A O 1 ATOM 29 C CB . ILE A 1 5 ? -54.257 -28.043 -20.046 1.00 87.09 ? 5 ILE A CB 1 ATOM 30 C CG1 . ILE A 1 5 ? -53.070 -28.804 -20.631 1.00 86.77 ? 5 ILE A CG1 1 ATOM 31 C CG2 . ILE A 1 5 ? -54.277 -26.619 -20.533 1.00 86.67 ? 5 ILE A CG2 1 ATOM 32 C CD1 . ILE A 1 5 ? -53.218 -30.303 -20.553 1.00 86.35 ? 5 ILE A CD1 1 ATOM 33 N N . ILE A 1 6 ? -54.678 -25.915 -17.551 1.00 86.26 ? 6 ILE A N 1 ATOM 34 C CA . ILE A 1 6 ? -55.543 -24.809 -17.156 1.00 85.57 ? 6 ILE A CA 1 ATOM 35 C C . ILE A 1 6 ? -55.351 -23.624 -18.092 1.00 85.56 ? 6 ILE A C 1 ATOM 36 O O . ILE A 1 6 ? -54.228 -23.330 -18.504 1.00 85.36 ? 6 ILE A O 1 ATOM 37 C CB . ILE A 1 6 ? -55.289 -24.376 -15.717 1.00 85.28 ? 6 ILE A CB 1 ATOM 38 C CG1 . ILE A 1 6 ? -55.479 -25.558 -14.791 1.00 84.52 ? 6 ILE A CG1 1 ATOM 39 C CG2 . ILE A 1 6 ? -56.286 -23.328 -15.315 1.00 85.24 ? 6 ILE A CG2 1 ATOM 40 C CD1 . ILE A 1 6 ? -56.921 -26.003 -14.738 1.00 84.28 ? 6 ILE A CD1 1 ATOM 41 N N . ALA A 1 7 ? -56.448 -22.955 -18.433 1.00 85.53 ? 7 ALA A N 1 ATOM 42 C CA . ALA A 1 7 ? -56.397 -21.871 -19.406 1.00 85.90 ? 7 ALA A CA 1 ATOM 43 C C . ALA A 1 7 ? -56.344 -20.522 -18.714 1.00 86.07 ? 7 ALA A C 1 ATOM 44 O O . ALA A 1 7 ? -57.379 -19.915 -18.485 1.00 86.40 ? 7 ALA A O 1 ATOM 45 C CB . ALA A 1 7 ? -57.606 -21.943 -20.343 1.00 85.68 ? 7 ALA A CB 1 ATOM 46 N N . THR A 1 8 ? -55.148 -20.045 -18.380 1.00 86.27 ? 8 THR A N 1 ATOM 47 C CA . THR A 1 8 ? -55.027 -18.768 -17.679 1.00 86.49 ? 8 THR A CA 1 ATOM 48 C C . THR A 1 8 ? -55.201 -17.636 -18.667 1.00 87.02 ? 8 THR A C 1 ATOM 49 O O . THR A 1 8 ? -54.943 -17.800 -19.854 1.00 87.26 ? 8 THR A O 1 ATOM 50 C CB . THR A 1 8 ? -53.668 -18.582 -17.014 1.00 86.28 ? 8 THR A CB 1 ATOM 51 O OG1 . THR A 1 8 ? -52.815 -17.832 -17.886 1.00 85.68 ? 8 THR A OG1 1 ATOM 52 C CG2 . THR A 1 8 ? -53.036 -19.922 -16.697 1.00 86.45 ? 8 THR A CG2 1 ATOM 53 N N . LYS A 1 9 ? -55.653 -16.491 -18.175 1.00 87.55 ? 9 LYS A N 1 ATOM 54 C CA . LYS A 1 9 ? -55.840 -15.333 -19.027 1.00 88.11 ? 9 LYS A CA 1 ATOM 55 C C . LYS A 1 9 ? -54.509 -14.952 -19.669 1.00 88.31 ? 9 LYS A C 1 ATOM 56 O O . LYS A 1 9 ? -54.415 -13.942 -20.353 1.00 88.50 ? 9 LYS A O 1 ATOM 57 C CB . LYS A 1 9 ? -56.415 -14.143 -18.240 1.00 88.30 ? 9 LYS A CB 1 ATOM 58 C CG . LYS A 1 9 ? -57.779 -14.379 -17.560 1.00 89.53 ? 9 LYS A CG 1 ATOM 59 C CD . LYS A 1 9 ? -58.917 -14.736 -18.546 1.00 91.68 ? 9 LYS A CD 1 ATOM 60 C CE . LYS A 1 9 ? -59.406 -13.539 -19.372 1.00 92.39 ? 9 LYS A CE 1 ATOM 61 N NZ . LYS A 1 9 ? -59.839 -12.373 -18.536 1.00 92.79 ? 9 LYS A NZ 1 ATOM 62 N N . ASN A 1 10 ? -53.473 -15.755 -19.452 1.00 88.63 ? 10 ASN A N 1 ATOM 63 C CA . ASN A 1 10 ? -52.198 -15.490 -20.107 1.00 88.97 ? 10 ASN A CA 1 ATOM 64 C C . ASN A 1 10 ? -51.757 -16.551 -21.087 1.00 89.05 ? 10 ASN A C 1 ATOM 65 O O . ASN A 1 10 ? -50.931 -16.286 -21.961 1.00 89.28 ? 10 ASN A O 1 ATOM 66 C CB . ASN A 1 10 ? -51.095 -15.271 -19.095 1.00 88.99 ? 10 ASN A CB 1 ATOM 67 C CG . ASN A 1 10 ? -50.703 -13.827 -18.982 1.00 90.02 ? 10 ASN A CG 1 ATOM 68 O OD1 . ASN A 1 10 ? -50.431 -13.336 -17.884 1.00 91.93 ? 10 ASN A OD1 1 ATOM 69 N ND2 . ASN A 1 10 ? -50.670 -13.127 -20.114 1.00 89.96 ? 10 ASN A ND2 1 ATOM 70 N N . GLY A 1 11 ? -52.301 -17.751 -20.931 1.00 88.81 ? 11 GLY A N 1 ATOM 71 C CA . GLY A 1 11 ? -51.951 -18.865 -21.791 1.00 88.53 ? 11 GLY A CA 1 ATOM 72 C C . GLY A 1 11 ? -52.253 -20.136 -21.044 1.00 88.44 ? 11 GLY A C 1 ATOM 73 O O . GLY A 1 11 ? -52.843 -20.103 -19.962 1.00 88.60 ? 11 GLY A O 1 ATOM 74 N N . LYS A 1 12 ? -51.851 -21.264 -21.606 1.00 88.03 ? 12 LYS A N 1 ATOM 75 C CA . LYS A 1 12 ? -52.128 -22.518 -20.949 1.00 87.57 ? 12 LYS A CA 1 ATOM 76 C C . LYS A 1 12 ? -50.947 -22.953 -20.093 1.00 87.08 ? 12 LYS A C 1 ATOM 77 O O . LYS A 1 12 ? -49.807 -22.552 -20.347 1.00 86.88 ? 12 LYS A O 1 ATOM 78 C CB . LYS A 1 12 ? -52.488 -23.589 -21.977 1.00 87.81 ? 12 LYS A CB 1 ATOM 79 C CG . LYS A 1 12 ? -53.768 -23.315 -22.739 1.00 88.28 ? 12 LYS A CG 1 ATOM 80 C CD . LYS A 1 12 ? -53.460 -22.824 -24.139 1.00 89.84 ? 12 LYS A CD 1 ATOM 81 C CE . LYS A 1 12 ? -54.693 -22.904 -25.044 1.00 90.58 ? 12 LYS A CE 1 ATOM 82 N NZ . LYS A 1 12 ? -55.384 -24.220 -25.004 1.00 89.97 ? 12 LYS A NZ 1 ATOM 83 N N . VAL A 1 13 ? -51.231 -23.766 -19.076 1.00 86.51 ? 13 VAL A N 1 ATOM 84 C CA . VAL A 1 13 ? -50.191 -24.304 -18.217 1.00 86.00 ? 13 VAL A CA 1 ATOM 85 C C . VAL A 1 13 ? -50.491 -25.735 -17.816 1.00 85.85 ? 13 VAL A C 1 ATOM 86 O O . VAL A 1 13 ? -51.600 -26.044 -17.379 1.00 85.60 ? 13 VAL A O 1 ATOM 87 C CB . VAL A 1 13 ? -50.013 -23.461 -16.950 1.00 85.91 ? 13 VAL A CB 1 ATOM 88 C CG1 . VAL A 1 13 ? -49.714 -22.036 -17.323 1.00 85.74 ? 13 VAL A CG1 1 ATOM 89 C CG2 . VAL A 1 13 ? -51.257 -23.520 -16.095 1.00 85.84 ? 13 VAL A CG2 1 ATOM 90 N N . ARG A 1 14 ? -49.496 -26.602 -17.974 1.00 85.73 ? 14 ARG A N 1 ATOM 91 C CA . ARG A 1 14 ? -49.631 -27.995 -17.604 1.00 85.78 ? 14 ARG A CA 1 ATOM 92 C C . ARG A 1 14 ? -49.190 -28.167 -16.171 1.00 85.45 ? 14 ARG A C 1 ATOM 93 O O . ARG A 1 14 ? -48.137 -27.672 -15.779 1.00 85.47 ? 14 ARG A O 1 ATOM 94 C CB . ARG A 1 14 ? -48.774 -28.878 -18.511 1.00 86.14 ? 14 ARG A CB 1 ATOM 95 C CG . ARG A 1 14 ? -48.751 -30.360 -18.113 1.00 87.63 ? 14 ARG A CG 1 ATOM 96 C CD . ARG A 1 14 ? -48.165 -31.269 -19.210 1.00 90.66 ? 14 ARG A CD 1 ATOM 97 N NE . ARG A 1 14 ? -48.936 -31.201 -20.454 1.00 93.60 ? 14 ARG A NE 1 ATOM 98 C CZ . ARG A 1 14 ? -48.591 -30.466 -21.510 1.00 94.77 ? 14 ARG A CZ 1 ATOM 99 N NH1 . ARG A 1 14 ? -47.471 -29.753 -21.485 1.00 95.40 ? 14 ARG A NH1 1 ATOM 100 N NH2 . ARG A 1 14 ? -49.355 -30.451 -22.595 1.00 94.42 ? 14 ARG A NH2 1 ATOM 101 N N . GLY A 1 15 ? -49.997 -28.875 -15.390 1.00 85.04 ? 15 GLY A N 1 ATOM 102 C CA . GLY A 1 15 ? -49.666 -29.156 -13.994 1.00 84.50 ? 15 GLY A CA 1 ATOM 103 C C . GLY A 1 15 ? -48.953 -30.476 -13.835 1.00 83.93 ? 15 GLY A C 1 ATOM 104 O O . GLY A 1 15 ? -48.315 -30.920 -14.756 1.00 83.82 ? 15 GLY A O 1 ATOM 105 N N . MET A 1 16 ? -49.046 -31.097 -12.665 1.00 83.71 ? 16 MET A N 1 ATOM 106 C CA . MET A 1 16 ? -48.465 -32.412 -12.477 1.00 83.83 ? 16 MET A CA 1 ATOM 107 C C . MET A 1 16 ? -49.062 -33.029 -11.241 1.00 83.99 ? 16 MET A C 1 ATOM 108 O O . MET A 1 16 ? -49.025 -32.423 -10.183 1.00 84.21 ? 16 MET A O 1 ATOM 109 C CB . MET A 1 16 ? -46.942 -32.331 -12.335 1.00 83.73 ? 16 MET A CB 1 ATOM 110 C CG . MET A 1 16 ? -46.442 -31.809 -10.995 1.00 84.34 ? 16 MET A CG 1 ATOM 111 S SD . MET A 1 16 ? -44.654 -31.447 -10.929 1.00 86.46 ? 16 MET A SD 1 ATOM 112 C CE . MET A 1 16 ? -43.932 -33.089 -10.739 1.00 85.74 ? 16 MET A CE 1 ATOM 113 N N . GLN A 1 17 ? -49.613 -34.232 -11.372 1.00 84.14 ? 17 GLN A N 1 ATOM 114 C CA . GLN A 1 17 ? -50.249 -34.912 -10.248 1.00 84.32 ? 17 GLN A CA 1 ATOM 115 C C . GLN A 1 17 ? -49.196 -35.282 -9.227 1.00 83.86 ? 17 GLN A C 1 ATOM 116 O O . GLN A 1 17 ? -48.087 -35.595 -9.588 1.00 84.22 ? 17 GLN A O 1 ATOM 117 C CB . GLN A 1 17 ? -50.966 -36.179 -10.723 1.00 84.64 ? 17 GLN A CB 1 ATOM 118 C CG . GLN A 1 17 ? -51.956 -35.970 -11.872 1.00 87.44 ? 17 GLN A CG 1 ATOM 119 C CD . GLN A 1 17 ? -53.085 -35.009 -11.510 1.00 91.14 ? 17 GLN A CD 1 ATOM 120 O OE1 . GLN A 1 17 ? -54.246 -35.412 -11.382 1.00 92.68 ? 17 GLN A OE1 1 ATOM 121 N NE2 . GLN A 1 17 ? -52.748 -33.730 -11.336 1.00 92.39 ? 17 GLN A NE2 1 ATOM 122 N N . LEU A 1 18 ? -49.528 -35.239 -7.950 1.00 83.47 ? 18 LEU A N 1 ATOM 123 C CA . LEU A 1 18 ? -48.618 -35.746 -6.953 1.00 83.07 ? 18 LEU A CA 1 ATOM 124 C C . LEU A 1 18 ? -49.437 -36.603 -6.005 1.00 83.10 ? 18 LEU A C 1 ATOM 125 O O . LEU A 1 18 ? -50.636 -36.381 -5.857 1.00 82.95 ? 18 LEU A O 1 ATOM 126 C CB . LEU A 1 18 ? -47.931 -34.595 -6.218 1.00 83.01 ? 18 LEU A CB 1 ATOM 127 C CG . LEU A 1 18 ? -47.394 -33.422 -7.048 1.00 82.93 ? 18 LEU A CG 1 ATOM 128 C CD1 . LEU A 1 18 ? -47.249 -32.183 -6.211 1.00 83.08 ? 18 LEU A CD1 1 ATOM 129 C CD2 . LEU A 1 18 ? -46.065 -33.731 -7.723 1.00 82.61 ? 18 LEU A CD2 1 ATOM 130 N N . THR A 1 19 ? -48.807 -37.597 -5.386 1.00 83.16 ? 19 THR A N 1 ATOM 131 C CA . THR A 1 19 ? -49.489 -38.424 -4.396 1.00 83.47 ? 19 THR A CA 1 ATOM 132 C C . THR A 1 19 ? -49.350 -37.773 -3.053 1.00 83.59 ? 19 THR A C 1 ATOM 133 O O . THR A 1 19 ? -48.245 -37.383 -2.670 1.00 84.00 ? 19 THR A O 1 ATOM 134 C CB . THR A 1 19 ? -48.852 -39.803 -4.268 1.00 83.46 ? 19 THR A CB 1 ATOM 135 O OG1 . THR A 1 19 ? -49.108 -40.547 -5.457 1.00 84.07 ? 19 THR A OG1 1 ATOM 136 C CG2 . THR A 1 19 ? -49.428 -40.552 -3.074 1.00 83.56 ? 19 THR A CG2 1 ATOM 137 N N . VAL A 1 20 ? -50.447 -37.651 -2.319 1.00 83.46 ? 20 VAL A N 1 ATOM 138 C CA . VAL A 1 20 ? -50.340 -37.103 -0.975 1.00 83.30 ? 20 VAL A CA 1 ATOM 139 C C . VAL A 1 20 ? -51.266 -37.825 -0.004 1.00 83.31 ? 20 VAL A C 1 ATOM 140 O O . VAL A 1 20 ? -52.487 -37.732 -0.113 1.00 83.20 ? 20 VAL A O 1 ATOM 141 C CB . VAL A 1 20 ? -50.607 -35.576 -0.949 1.00 83.27 ? 20 VAL A CB 1 ATOM 142 C CG1 . VAL A 1 20 ? -49.877 -34.952 0.211 1.00 83.48 ? 20 VAL A CG1 1 ATOM 143 C CG2 . VAL A 1 20 ? -50.155 -34.915 -2.233 1.00 82.52 ? 20 VAL A CG2 1 ATOM 144 N N . PHE A 1 21 ? -50.682 -38.554 0.940 1.00 83.37 ? 21 PHE A N 1 ATOM 145 C CA . PHE A 1 21 ? -51.476 -39.320 1.890 1.00 83.67 ? 21 PHE A CA 1 ATOM 146 C C . PHE A 1 21 ? -52.595 -40.045 1.167 1.00 83.53 ? 21 PHE A C 1 ATOM 147 O O . PHE A 1 21 ? -53.767 -39.864 1.498 1.00 83.71 ? 21 PHE A O 1 ATOM 148 C CB . PHE A 1 21 ? -52.117 -38.401 2.919 1.00 83.88 ? 21 PHE A CB 1 ATOM 149 C CG . PHE A 1 21 ? -51.160 -37.486 3.586 1.00 84.76 ? 21 PHE A CG 1 ATOM 150 C CD1 . PHE A 1 21 ? -51.290 -36.119 3.456 1.00 84.86 ? 21 PHE A CD1 1 ATOM 151 C CD2 . PHE A 1 21 ? -50.129 -37.991 4.358 1.00 85.73 ? 21 PHE A CD2 1 ATOM 152 C CE1 . PHE A 1 21 ? -50.406 -35.269 4.085 1.00 85.53 ? 21 PHE A CE1 1 ATOM 153 C CE2 . PHE A 1 21 ? -49.232 -37.142 4.987 1.00 85.76 ? 21 PHE A CE2 1 ATOM 154 C CZ . PHE A 1 21 ? -49.372 -35.778 4.849 1.00 85.52 ? 21 PHE A CZ 1 ATOM 155 N N . GLY A 1 22 ? -52.242 -40.855 0.179 1.00 83.15 ? 22 GLY A N 1 ATOM 156 C CA . GLY A 1 22 ? -53.244 -41.555 -0.610 1.00 82.62 ? 22 GLY A CA 1 ATOM 157 C C . GLY A 1 22 ? -54.266 -40.608 -1.218 1.00 82.12 ? 22 GLY A C 1 ATOM 158 O O . GLY A 1 22 ? -55.472 -40.796 -1.076 1.00 82.40 ? 22 GLY A O 1 ATOM 159 N N . GLY A 1 23 ? -53.785 -39.580 -1.899 1.00 81.41 ? 23 GLY A N 1 ATOM 160 C CA . GLY A 1 23 ? -54.668 -38.660 -2.582 1.00 80.20 ? 23 GLY A CA 1 ATOM 161 C C . GLY A 1 23 ? -53.897 -37.946 -3.656 1.00 79.53 ? 23 GLY A C 1 ATOM 162 O O . GLY A 1 23 ? -52.670 -37.984 -3.692 1.00 79.25 ? 23 GLY A O 1 ATOM 163 N N . THR A 1 24 ? -54.621 -37.292 -4.544 1.00 78.98 ? 24 THR A N 1 ATOM 164 C CA . THR A 1 24 ? -53.977 -36.542 -5.591 1.00 78.60 ? 24 THR A CA 1 ATOM 165 C C . THR A 1 24 ? -54.071 -35.052 -5.299 1.00 78.27 ? 24 THR A C 1 ATOM 166 O O . THR A 1 24 ? -55.089 -34.558 -4.788 1.00 78.47 ? 24 THR A O 1 ATOM 167 C CB . THR A 1 24 ? -54.602 -36.850 -6.960 1.00 78.71 ? 24 THR A CB 1 ATOM 168 O OG1 . THR A 1 24 ? -54.598 -38.264 -7.160 1.00 78.70 ? 24 THR A OG1 1 ATOM 169 C CG2 . THR A 1 24 ? -53.825 -36.162 -8.098 1.00 78.43 ? 24 THR A CG2 1 ATOM 170 N N . VAL A 1 25 ? -52.986 -34.345 -5.599 1.00 77.31 ? 25 VAL A N 1 ATOM 171 C CA . VAL A 1 25 ? -52.999 -32.889 -5.613 1.00 76.31 ? 25 VAL A CA 1 ATOM 172 C C . VAL A 1 25 ? -52.310 -32.458 -6.896 1.00 75.66 ? 25 VAL A C 1 ATOM 173 O O . VAL A 1 25 ? -51.287 -33.018 -7.268 1.00 75.65 ? 25 VAL A O 1 ATOM 174 C CB . VAL A 1 25 ? -52.279 -32.268 -4.393 1.00 76.23 ? 25 VAL A CB 1 ATOM 175 C CG1 . VAL A 1 25 ? -52.063 -30.790 -4.614 1.00 76.08 ? 25 VAL A CG1 1 ATOM 176 C CG2 . VAL A 1 25 ? -53.067 -32.491 -3.132 1.00 75.56 ? 25 VAL A CG2 1 ATOM 177 N N . THR A 1 26 ? -52.892 -31.488 -7.584 1.00 74.72 ? 26 THR A N 1 ATOM 178 C CA . THR A 1 26 ? -52.281 -30.949 -8.776 1.00 73.95 ? 26 THR A CA 1 ATOM 179 C C . THR A 1 26 ? -51.373 -29.782 -8.406 1.00 73.51 ? 26 THR A C 1 ATOM 180 O O . THR A 1 26 ? -51.799 -28.844 -7.752 1.00 73.22 ? 26 THR A O 1 ATOM 181 C CB . THR A 1 26 ? -53.340 -30.456 -9.771 1.00 73.99 ? 26 THR A CB 1 ATOM 182 O OG1 . THR A 1 26 ? -54.342 -31.462 -9.944 1.00 73.56 ? 26 THR A OG1 1 ATOM 183 C CG2 . THR A 1 26 ? -52.703 -30.129 -11.098 1.00 73.26 ? 26 THR A CG2 1 ATOM 184 N N . ALA A 1 27 ? -50.120 -29.850 -8.837 1.00 73.17 ? 27 ALA A N 1 ATOM 185 C CA . ALA A 1 27 ? -49.145 -28.792 -8.595 1.00 72.47 ? 27 ALA A CA 1 ATOM 186 C C . ALA A 1 27 ? -48.807 -28.074 -9.897 1.00 72.17 ? 27 ALA A C 1 ATOM 187 O O . ALA A 1 27 ? -48.469 -28.697 -10.897 1.00 72.12 ? 27 ALA A O 1 ATOM 188 C CB . ALA A 1 27 ? -47.886 -29.366 -7.967 1.00 72.13 ? 27 ALA A CB 1 ATOM 189 N N . PHE A 1 28 ? -48.914 -26.756 -9.873 1.00 71.86 ? 28 PHE A N 1 ATOM 190 C CA . PHE A 1 28 ? -48.450 -25.933 -10.961 1.00 71.60 ? 28 PHE A CA 1 ATOM 191 C C . PHE A 1 28 ? -47.253 -25.099 -10.518 1.00 71.15 ? 28 PHE A C 1 ATOM 192 O O . PHE A 1 28 ? -47.433 -23.951 -10.084 1.00 70.99 ? 28 PHE A O 1 ATOM 193 C CB . PHE A 1 28 ? -49.563 -25.009 -11.394 1.00 71.90 ? 28 PHE A CB 1 ATOM 194 C CG . PHE A 1 28 ? -50.710 -25.717 -12.028 1.00 73.42 ? 28 PHE A CG 1 ATOM 195 C CD1 . PHE A 1 28 ? -51.618 -26.411 -11.245 1.00 75.16 ? 28 PHE A CD1 1 ATOM 196 C CD2 . PHE A 1 28 ? -50.896 -25.688 -13.408 1.00 73.40 ? 28 PHE A CD2 1 ATOM 197 C CE1 . PHE A 1 28 ? -52.708 -27.075 -11.824 1.00 75.81 ? 28 PHE A CE1 1 ATOM 198 C CE2 . PHE A 1 28 ? -51.976 -26.351 -13.990 1.00 74.59 ? 28 PHE A CE2 1 ATOM 199 C CZ . PHE A 1 28 ? -52.885 -27.044 -13.192 1.00 75.27 ? 28 PHE A CZ 1 ATOM 200 N N . LEU A 1 29 ? -46.048 -25.679 -10.627 1.00 70.39 ? 29 LEU A N 1 ATOM 201 C CA . LEU A 1 29 ? -44.815 -25.024 -10.200 1.00 69.70 ? 29 LEU A CA 1 ATOM 202 C C . LEU A 1 29 ? -44.229 -24.121 -11.277 1.00 69.69 ? 29 LEU A C 1 ATOM 203 O O . LEU A 1 29 ? -44.258 -24.431 -12.448 1.00 69.89 ? 29 LEU A O 1 ATOM 204 C CB . LEU A 1 29 ? -43.779 -26.050 -9.745 1.00 69.27 ? 29 LEU A CB 1 ATOM 205 C CG . LEU A 1 29 ? -44.241 -27.147 -8.778 1.00 68.97 ? 29 LEU A CG 1 ATOM 206 C CD1 . LEU A 1 29 ? -43.075 -27.873 -8.137 1.00 67.30 ? 29 LEU A CD1 1 ATOM 207 C CD2 . LEU A 1 29 ? -45.132 -26.602 -7.695 1.00 69.53 ? 29 LEU A CD2 1 ATOM 208 N N . GLY A 1 30 ? -43.726 -22.972 -10.865 1.00 69.82 ? 30 GLY A N 1 ATOM 209 C CA . GLY A 1 30 ? -42.976 -22.104 -11.750 1.00 70.17 ? 30 GLY A CA 1 ATOM 210 C C . GLY A 1 30 ? -43.717 -21.294 -12.802 1.00 70.51 ? 30 GLY A C 1 ATOM 211 O O . GLY A 1 30 ? -43.136 -20.941 -13.834 1.00 70.97 ? 30 GLY A O 1 ATOM 212 N N . ILE A 1 31 ? -44.982 -20.967 -12.567 1.00 70.43 ? 31 ILE A N 1 ATOM 213 C CA . ILE A 1 31 ? -45.701 -20.105 -13.504 1.00 70.13 ? 31 ILE A CA 1 ATOM 214 C C . ILE A 1 31 ? -45.172 -18.683 -13.426 1.00 70.75 ? 31 ILE A C 1 ATOM 215 O O . ILE A 1 31 ? -45.143 -18.105 -12.341 1.00 70.93 ? 31 ILE A O 1 ATOM 216 C CB . ILE A 1 31 ? -47.177 -20.027 -13.177 1.00 69.58 ? 31 ILE A CB 1 ATOM 217 C CG1 . ILE A 1 31 ? -47.799 -21.411 -13.148 1.00 68.57 ? 31 ILE A CG1 1 ATOM 218 C CG2 . ILE A 1 31 ? -47.869 -19.164 -14.175 1.00 69.20 ? 31 ILE A CG2 1 ATOM 219 C CD1 . ILE A 1 31 ? -49.229 -21.373 -12.712 1.00 67.03 ? 31 ILE A CD1 1 ATOM 220 N N . PRO A 1 32 ? -44.764 -18.108 -14.576 1.00 71.19 ? 32 PRO A N 1 ATOM 221 C CA . PRO A 1 32 ? -44.311 -16.713 -14.621 1.00 71.40 ? 32 PRO A CA 1 ATOM 222 C C . PRO A 1 32 ? -45.484 -15.779 -14.407 1.00 71.61 ? 32 PRO A C 1 ATOM 223 O O . PRO A 1 32 ? -46.527 -15.968 -15.032 1.00 71.57 ? 32 PRO A O 1 ATOM 224 C CB . PRO A 1 32 ? -43.804 -16.548 -16.056 1.00 71.33 ? 32 PRO A CB 1 ATOM 225 C CG . PRO A 1 32 ? -44.575 -17.526 -16.836 1.00 71.20 ? 32 PRO A CG 1 ATOM 226 C CD . PRO A 1 32 ? -44.815 -18.712 -15.917 1.00 71.17 ? 32 PRO A CD 1 ATOM 227 N N . TYR A 1 33 ? -45.321 -14.784 -13.539 1.00 71.90 ? 33 TYR A N 1 ATOM 228 C CA . TYR A 1 33 ? -46.381 -13.811 -13.312 1.00 72.06 ? 33 TYR A CA 1 ATOM 229 C C . TYR A 1 33 ? -45.990 -12.404 -13.726 1.00 72.58 ? 33 TYR A C 1 ATOM 230 O O . TYR A 1 33 ? -46.792 -11.490 -13.662 1.00 72.54 ? 33 TYR A O 1 ATOM 231 C CB . TYR A 1 33 ? -46.850 -13.840 -11.862 1.00 71.77 ? 33 TYR A CB 1 ATOM 232 C CG . TYR A 1 33 ? -45.835 -13.360 -10.857 1.00 70.72 ? 33 TYR A CG 1 ATOM 233 C CD1 . TYR A 1 33 ? -44.994 -14.251 -10.209 1.00 69.30 ? 33 TYR A CD1 1 ATOM 234 C CD2 . TYR A 1 33 ? -45.728 -12.011 -10.542 1.00 69.24 ? 33 TYR A CD2 1 ATOM 235 C CE1 . TYR A 1 33 ? -44.077 -13.799 -9.282 1.00 68.96 ? 33 TYR A CE1 1 ATOM 236 C CE2 . TYR A 1 33 ? -44.813 -11.560 -9.629 1.00 67.79 ? 33 TYR A CE2 1 ATOM 237 C CZ . TYR A 1 33 ? -43.995 -12.449 -9.000 1.00 68.25 ? 33 TYR A CZ 1 ATOM 238 O OH . TYR A 1 33 ? -43.082 -11.976 -8.087 1.00 68.77 ? 33 TYR A OH 1 ATOM 239 N N . ALA A 1 34 ? -44.752 -12.233 -14.154 1.00 73.62 ? 34 ALA A N 1 ATOM 240 C CA . ALA A 1 34 ? -44.319 -10.967 -14.722 1.00 74.67 ? 34 ALA A CA 1 ATOM 241 C C . ALA A 1 34 ? -43.172 -11.177 -15.687 1.00 75.45 ? 34 ALA A C 1 ATOM 242 O O . ALA A 1 34 ? -42.657 -12.279 -15.846 1.00 75.81 ? 34 ALA A O 1 ATOM 243 C CB . ALA A 1 34 ? -43.934 -9.980 -13.639 1.00 74.56 ? 34 ALA A CB 1 ATOM 244 N N . GLN A 1 35 ? -42.768 -10.094 -16.319 1.00 76.22 ? 35 GLN A N 1 ATOM 245 C CA . GLN A 1 35 ? -41.886 -10.155 -17.454 1.00 77.11 ? 35 GLN A CA 1 ATOM 246 C C . GLN A 1 35 ? -40.452 -9.935 -16.968 1.00 77.12 ? 35 GLN A C 1 ATOM 247 O O . GLN A 1 35 ? -40.148 -8.890 -16.411 1.00 77.54 ? 35 GLN A O 1 ATOM 248 C CB . GLN A 1 35 ? -42.361 -9.082 -18.421 1.00 77.13 ? 35 GLN A CB 1 ATOM 249 C CG . GLN A 1 35 ? -41.480 -8.757 -19.572 1.00 79.36 ? 35 GLN A CG 1 ATOM 250 C CD . GLN A 1 35 ? -41.792 -7.364 -20.071 1.00 82.30 ? 35 GLN A CD 1 ATOM 251 O OE1 . GLN A 1 35 ? -42.961 -7.002 -20.215 1.00 82.81 ? 35 GLN A OE1 1 ATOM 252 N NE2 . GLN A 1 35 ? -40.754 -6.559 -20.302 1.00 83.54 ? 35 GLN A NE2 1 ATOM 253 N N . PRO A 1 36 ? -39.562 -10.922 -17.164 1.00 77.00 ? 36 PRO A N 1 ATOM 254 C CA . PRO A 1 36 ? -38.292 -10.898 -16.440 1.00 76.96 ? 36 PRO A CA 1 ATOM 255 C C . PRO A 1 36 ? -37.643 -9.524 -16.367 1.00 77.01 ? 36 PRO A C 1 ATOM 256 O O . PRO A 1 36 ? -37.446 -8.879 -17.382 1.00 77.12 ? 36 PRO A O 1 ATOM 257 C CB . PRO A 1 36 ? -37.438 -11.876 -17.226 1.00 76.83 ? 36 PRO A CB 1 ATOM 258 C CG . PRO A 1 36 ? -38.420 -12.849 -17.744 1.00 76.83 ? 36 PRO A CG 1 ATOM 259 C CD . PRO A 1 36 ? -39.629 -12.049 -18.104 1.00 76.89 ? 36 PRO A CD 1 ATOM 260 N N . PRO A 1 37 ? -37.300 -9.081 -15.156 1.00 77.11 ? 37 PRO A N 1 ATOM 261 C CA . PRO A 1 37 ? -36.855 -7.729 -14.938 1.00 77.39 ? 37 PRO A CA 1 ATOM 262 C C . PRO A 1 37 ? -35.383 -7.600 -15.256 1.00 77.75 ? 37 PRO A C 1 ATOM 263 O O . PRO A 1 37 ? -34.576 -7.495 -14.318 1.00 77.67 ? 37 PRO A O 1 ATOM 264 C CB . PRO A 1 37 ? -37.010 -7.589 -13.439 1.00 77.34 ? 37 PRO A CB 1 ATOM 265 C CG . PRO A 1 37 ? -36.570 -8.902 -12.964 1.00 77.20 ? 37 PRO A CG 1 ATOM 266 C CD . PRO A 1 37 ? -37.137 -9.886 -13.940 1.00 76.98 ? 37 PRO A CD 1 ATOM 267 N N . LEU A 1 38 ? -35.040 -7.568 -16.550 1.00 78.04 ? 38 LEU A N 1 ATOM 268 C CA . LEU A 1 38 ? -33.645 -7.681 -16.999 1.00 77.95 ? 38 LEU A CA 1 ATOM 269 C C . LEU A 1 38 ? -33.043 -6.454 -17.658 1.00 78.22 ? 38 LEU A C 1 ATOM 270 O O . LEU A 1 38 ? -33.685 -5.742 -18.425 1.00 77.59 ? 38 LEU A O 1 ATOM 271 C CB . LEU A 1 38 ? -33.501 -8.852 -17.947 1.00 77.76 ? 38 LEU A CB 1 ATOM 272 C CG . LEU A 1 38 ? -33.751 -10.211 -17.318 1.00 77.84 ? 38 LEU A CG 1 ATOM 273 C CD1 . LEU A 1 38 ? -33.993 -11.248 -18.409 1.00 77.67 ? 38 LEU A CD1 1 ATOM 274 C CD2 . LEU A 1 38 ? -32.589 -10.601 -16.403 1.00 78.02 ? 38 LEU A CD2 1 ATOM 275 N N . GLY A 1 39 ? -31.775 -6.233 -17.355 1.00 79.00 ? 39 GLY A N 1 ATOM 276 C CA . GLY A 1 39 ? -31.037 -5.135 -17.954 1.00 80.32 ? 39 GLY A CA 1 ATOM 277 C C . GLY A 1 39 ? -31.739 -3.812 -17.799 1.00 81.12 ? 39 GLY A C 1 ATOM 278 O O . GLY A 1 39 ? -31.569 -3.110 -16.804 1.00 81.62 ? 39 GLY A O 1 ATOM 279 N N . ARG A 1 40 ? -32.538 -3.468 -18.789 1.00 81.69 ? 40 ARG A N 1 ATOM 280 C CA . ARG A 1 40 ? -33.241 -2.201 -18.762 1.00 82.53 ? 40 ARG A CA 1 ATOM 281 C C . ARG A 1 40 ? -34.331 -2.176 -17.676 1.00 81.72 ? 40 ARG A C 1 ATOM 282 O O . ARG A 1 40 ? -34.734 -1.104 -17.207 1.00 81.66 ? 40 ARG A O 1 ATOM 283 C CB . ARG A 1 40 ? -33.802 -1.909 -20.155 1.00 83.22 ? 40 ARG A CB 1 ATOM 284 C CG . ARG A 1 40 ? -33.886 -3.180 -21.027 1.00 86.97 ? 40 ARG A CG 1 ATOM 285 C CD . ARG A 1 40 ? -34.274 -2.902 -22.494 1.00 92.34 ? 40 ARG A CD 1 ATOM 286 N NE . ARG A 1 40 ? -35.411 -1.985 -22.572 1.00 96.90 ? 40 ARG A NE 1 ATOM 287 C CZ . ARG A 1 40 ? -36.681 -2.327 -22.339 1.00 99.33 ? 40 ARG A CZ 1 ATOM 288 N NH1 . ARG A 1 40 ? -37.001 -3.584 -22.024 1.00 100.31 ? 40 ARG A NH1 1 ATOM 289 N NH2 . ARG A 1 40 ? -37.637 -1.405 -22.420 1.00 100.41 ? 40 ARG A NH2 1 ATOM 290 N N . LEU A 1 41 ? -34.785 -3.353 -17.255 1.00 80.68 ? 41 LEU A N 1 ATOM 291 C CA . LEU A 1 41 ? -35.856 -3.427 -16.276 1.00 79.46 ? 41 LEU A CA 1 ATOM 292 C C . LEU A 1 41 ? -35.354 -3.638 -14.863 1.00 78.93 ? 41 LEU A C 1 ATOM 293 O O . LEU A 1 41 ? -36.122 -3.567 -13.921 1.00 79.09 ? 41 LEU A O 1 ATOM 294 C CB . LEU A 1 41 ? -36.859 -4.514 -16.652 1.00 79.39 ? 41 LEU A CB 1 ATOM 295 C CG . LEU A 1 41 ? -37.717 -4.183 -17.879 1.00 79.38 ? 41 LEU A CG 1 ATOM 296 C CD1 . LEU A 1 41 ? -38.778 -5.248 -18.162 1.00 78.99 ? 41 LEU A CD1 1 ATOM 297 C CD2 . LEU A 1 41 ? -38.377 -2.825 -17.713 1.00 79.29 ? 41 LEU A CD2 1 ATOM 298 N N . ARG A 1 42 ? -34.068 -3.894 -14.698 1.00 78.19 ? 42 ARG A N 1 ATOM 299 C CA . ARG A 1 42 ? -33.536 -4.042 -13.353 1.00 77.55 ? 42 ARG A CA 1 ATOM 300 C C . ARG A 1 42 ? -33.857 -2.812 -12.506 1.00 77.55 ? 42 ARG A C 1 ATOM 301 O O . ARG A 1 42 ? -33.700 -1.677 -12.952 1.00 77.69 ? 42 ARG A O 1 ATOM 302 C CB . ARG A 1 42 ? -32.029 -4.284 -13.374 1.00 77.19 ? 42 ARG A CB 1 ATOM 303 C CG . ARG A 1 42 ? -31.444 -4.492 -11.999 1.00 75.62 ? 42 ARG A CG 1 ATOM 304 C CD . ARG A 1 42 ? -29.948 -4.457 -12.029 1.00 73.90 ? 42 ARG A CD 1 ATOM 305 N NE . ARG A 1 42 ? -29.360 -5.709 -12.480 1.00 71.84 ? 42 ARG A NE 1 ATOM 306 C CZ . ARG A 1 42 ? -28.098 -5.838 -12.876 1.00 70.41 ? 42 ARG A CZ 1 ATOM 307 N NH1 . ARG A 1 42 ? -27.298 -4.779 -12.892 1.00 69.61 ? 42 ARG A NH1 1 ATOM 308 N NH2 . ARG A 1 42 ? -27.645 -7.021 -13.268 1.00 69.11 ? 42 ARG A NH2 1 ATOM 309 N N . PHE A 1 43 ? -34.306 -3.042 -11.281 1.00 77.32 ? 43 PHE A N 1 ATOM 310 C CA . PHE A 1 43 ? -34.665 -1.953 -10.372 1.00 77.28 ? 43 PHE A CA 1 ATOM 311 C C . PHE A 1 43 ? -36.005 -1.295 -10.670 1.00 77.49 ? 43 PHE A C 1 ATOM 312 O O . PHE A 1 43 ? -36.318 -0.277 -10.084 1.00 77.46 ? 43 PHE A O 1 ATOM 313 C CB . PHE A 1 43 ? -33.597 -0.858 -10.340 1.00 76.98 ? 43 PHE A CB 1 ATOM 314 C CG . PHE A 1 43 ? -32.264 -1.329 -9.865 1.00 76.63 ? 43 PHE A CG 1 ATOM 315 C CD1 . PHE A 1 43 ? -32.139 -2.001 -8.660 1.00 76.68 ? 43 PHE A CD1 1 ATOM 316 C CD2 . PHE A 1 43 ? -31.126 -1.090 -10.610 1.00 75.24 ? 43 PHE A CD2 1 ATOM 317 C CE1 . PHE A 1 43 ? -30.900 -2.442 -8.224 1.00 76.14 ? 43 PHE A CE1 1 ATOM 318 C CE2 . PHE A 1 43 ? -29.900 -1.519 -10.171 1.00 74.43 ? 43 PHE A CE2 1 ATOM 319 C CZ . PHE A 1 43 ? -29.784 -2.198 -8.983 1.00 74.56 ? 43 PHE A CZ 1 ATOM 320 N N . LYS A 1 44 ? -36.797 -1.849 -11.573 1.00 77.88 ? 44 LYS A N 1 ATOM 321 C CA . LYS A 1 44 ? -38.070 -1.229 -11.865 1.00 78.45 ? 44 LYS A CA 1 ATOM 322 C C . LYS A 1 44 ? -39.225 -2.018 -11.305 1.00 78.60 ? 44 LYS A C 1 ATOM 323 O O . LYS A 1 44 ? -39.068 -3.156 -10.882 1.00 78.38 ? 44 LYS A O 1 ATOM 324 C CB . LYS A 1 44 ? -38.255 -1.033 -13.359 1.00 78.60 ? 44 LYS A CB 1 ATOM 325 C CG . LYS A 1 44 ? -37.526 0.166 -13.895 1.00 79.99 ? 44 LYS A CG 1 ATOM 326 C CD . LYS A 1 44 ? -38.094 0.531 -15.223 1.00 82.79 ? 44 LYS A CD 1 ATOM 327 C CE . LYS A 1 44 ? -37.419 1.745 -15.800 1.00 85.12 ? 44 LYS A CE 1 ATOM 328 N NZ . LYS A 1 44 ? -37.900 2.004 -17.207 1.00 87.48 ? 44 LYS A NZ 1 ATOM 329 N N . LYS A 1 45 ? -40.392 -1.393 -11.286 1.00 79.08 ? 45 LYS A N 1 ATOM 330 C CA . LYS A 1 45 ? -41.598 -2.110 -10.923 1.00 79.48 ? 45 LYS A CA 1 ATOM 331 C C . LYS A 1 45 ? -41.824 -3.246 -11.931 1.00 80.15 ? 45 LYS A C 1 ATOM 332 O O . LYS A 1 45 ? -41.501 -3.114 -13.120 1.00 79.85 ? 45 LYS A O 1 ATOM 333 C CB . LYS A 1 45 ? -42.812 -1.166 -10.847 1.00 79.30 ? 45 LYS A CB 1 ATOM 334 C CG . LYS A 1 45 ? -42.737 -0.105 -9.737 1.00 77.97 ? 45 LYS A CG 1 ATOM 335 C CD . LYS A 1 45 ? -44.102 0.136 -9.085 1.00 75.52 ? 45 LYS A CD 1 ATOM 336 C CE . LYS A 1 45 ? -44.841 1.353 -9.619 1.00 75.33 ? 45 LYS A CE 1 ATOM 337 N NZ . LYS A 1 45 ? -46.316 1.252 -9.433 1.00 74.36 ? 45 LYS A NZ 1 ATOM 338 N N . PRO A 1 46 ? -42.345 -4.381 -11.438 1.00 80.98 ? 46 PRO A N 1 ATOM 339 C CA . PRO A 1 46 ? -42.630 -5.548 -12.253 1.00 81.84 ? 46 PRO A CA 1 ATOM 340 C C . PRO A 1 46 ? -43.524 -5.199 -13.411 1.00 83.00 ? 46 PRO A C 1 ATOM 341 O O . PRO A 1 46 ? -44.483 -4.479 -13.233 1.00 82.77 ? 46 PRO A O 1 ATOM 342 C CB . PRO A 1 46 ? -43.383 -6.479 -11.292 1.00 81.75 ? 46 PRO A CB 1 ATOM 343 C CG . PRO A 1 46 ? -43.502 -5.758 -9.984 1.00 81.19 ? 46 PRO A CG 1 ATOM 344 C CD . PRO A 1 46 ? -42.503 -4.659 -10.000 1.00 80.89 ? 46 PRO A CD 1 ATOM 345 N N . GLN A 1 47 ? -43.224 -5.736 -14.585 1.00 84.95 ? 47 GLN A N 1 ATOM 346 C CA . GLN A 1 47 ? -43.934 -5.377 -15.808 1.00 86.82 ? 47 GLN A CA 1 ATOM 347 C C . GLN A 1 47 ? -44.948 -6.405 -16.235 1.00 88.11 ? 47 GLN A C 1 ATOM 348 O O . GLN A 1 47 ? -44.737 -7.601 -16.055 1.00 88.47 ? 47 GLN A O 1 ATOM 349 C CB . GLN A 1 47 ? -42.938 -5.215 -16.937 1.00 86.88 ? 47 GLN A CB 1 ATOM 350 C CG . GLN A 1 47 ? -42.100 -3.979 -16.830 1.00 88.21 ? 47 GLN A CG 1 ATOM 351 C CD . GLN A 1 47 ? -42.886 -2.743 -17.163 1.00 90.12 ? 47 GLN A CD 1 ATOM 352 O OE1 . GLN A 1 47 ? -43.762 -2.330 -16.407 1.00 90.48 ? 47 GLN A OE1 1 ATOM 353 N NE2 . GLN A 1 47 ? -42.582 -2.138 -18.306 1.00 91.36 ? 47 GLN A NE2 1 ATOM 354 N N . SER A 1 48 ? -46.033 -5.933 -16.834 1.00 89.66 ? 48 SER A N 1 ATOM 355 C CA . SER A 1 48 ? -47.080 -6.803 -17.375 1.00 91.13 ? 48 SER A CA 1 ATOM 356 C C . SER A 1 48 ? -46.560 -7.999 -18.150 1.00 92.17 ? 48 SER A C 1 ATOM 357 O O . SER A 1 48 ? -45.553 -7.903 -18.850 1.00 92.33 ? 48 SER A O 1 ATOM 358 C CB . SER A 1 48 ? -47.964 -6.004 -18.322 1.00 91.17 ? 48 SER A CB 1 ATOM 359 O OG . SER A 1 48 ? -49.270 -5.861 -17.801 1.00 92.37 ? 48 SER A OG 1 ATOM 360 N N . LEU A 1 49 ? -47.276 -9.114 -18.069 1.00 93.64 ? 49 LEU A N 1 ATOM 361 C CA . LEU A 1 49 ? -46.938 -10.292 -18.873 1.00 95.25 ? 49 LEU A CA 1 ATOM 362 C C . LEU A 1 49 ? -47.682 -10.327 -20.227 1.00 96.31 ? 49 LEU A C 1 ATOM 363 O O . LEU A 1 49 ? -48.898 -10.541 -20.276 1.00 96.40 ? 49 LEU A O 1 ATOM 364 C CB . LEU A 1 49 ? -47.246 -11.553 -18.068 1.00 95.16 ? 49 LEU A CB 1 ATOM 365 C CG . LEU A 1 49 ? -46.373 -12.772 -18.339 1.00 95.70 ? 49 LEU A CG 1 ATOM 366 C CD1 . LEU A 1 49 ? -44.888 -12.397 -18.277 1.00 95.58 ? 49 LEU A CD1 1 ATOM 367 C CD2 . LEU A 1 49 ? -46.720 -13.893 -17.349 1.00 95.38 ? 49 LEU A CD2 1 ATOM 368 N N . THR A 1 50 ? -46.962 -10.103 -21.326 1.00 97.69 ? 50 THR A N 1 ATOM 369 C CA . THR A 1 50 ? -47.583 -10.205 -22.656 1.00 98.86 ? 50 THR A CA 1 ATOM 370 C C . THR A 1 50 ? -47.941 -11.661 -22.949 1.00 99.44 ? 50 THR A C 1 ATOM 371 O O . THR A 1 50 ? -47.063 -12.533 -23.019 1.00 99.55 ? 50 THR A O 1 ATOM 372 C CB . THR A 1 50 ? -46.677 -9.658 -23.789 1.00 99.05 ? 50 THR A CB 1 ATOM 373 O OG1 . THR A 1 50 ? -45.353 -10.203 -23.651 1.00 99.32 ? 50 THR A OG1 1 ATOM 374 C CG2 . THR A 1 50 ? -46.638 -8.102 -23.788 1.00 98.95 ? 50 THR A CG2 1 ATOM 375 N N . LYS A 1 51 ? -49.234 -11.915 -23.122 1.00 100.08 ? 51 LYS A N 1 ATOM 376 C CA . LYS A 1 51 ? -49.753 -13.284 -23.238 1.00 100.87 ? 51 LYS A CA 1 ATOM 377 C C . LYS A 1 51 ? -48.870 -14.194 -24.084 1.00 100.85 ? 51 LYS A C 1 ATOM 378 O O . LYS A 1 51 ? -48.594 -13.895 -25.243 1.00 100.89 ? 51 LYS A O 1 ATOM 379 C CB . LYS A 1 51 ? -51.176 -13.284 -23.821 1.00 101.19 ? 51 LYS A CB 1 ATOM 380 C CG . LYS A 1 51 ? -51.940 -11.947 -23.712 1.00 102.64 ? 51 LYS A CG 1 ATOM 381 C CD . LYS A 1 51 ? -51.968 -11.186 -25.054 1.00 104.20 ? 51 LYS A CD 1 ATOM 382 C CE . LYS A 1 51 ? -52.941 -10.003 -25.026 1.00 104.19 ? 51 LYS A CE 1 ATOM 383 N NZ . LYS A 1 51 ? -52.317 -8.810 -24.405 1.00 103.95 ? 51 LYS A NZ 1 ATOM 384 N N . TRP A 1 52 ? -48.434 -15.312 -23.514 1.00 101.00 ? 52 TRP A N 1 ATOM 385 C CA . TRP A 1 52 ? -47.681 -16.283 -24.303 1.00 101.21 ? 52 TRP A CA 1 ATOM 386 C C . TRP A 1 52 ? -48.607 -17.165 -25.146 1.00 101.52 ? 52 TRP A C 1 ATOM 387 O O . TRP A 1 52 ? -49.769 -17.402 -24.801 1.00 101.45 ? 52 TRP A O 1 ATOM 388 C CB . TRP A 1 52 ? -46.762 -17.149 -23.436 1.00 100.97 ? 52 TRP A CB 1 ATOM 389 C CG . TRP A 1 52 ? -47.490 -18.154 -22.627 1.00 100.57 ? 52 TRP A CG 1 ATOM 390 C CD1 . TRP A 1 52 ? -47.963 -19.368 -23.044 1.00 100.39 ? 52 TRP A CD1 1 ATOM 391 C CD2 . TRP A 1 52 ? -47.838 -18.037 -21.248 1.00 100.36 ? 52 TRP A CD2 1 ATOM 392 N NE1 . TRP A 1 52 ? -48.587 -20.018 -22.001 1.00 100.22 ? 52 TRP A NE1 1 ATOM 393 C CE2 . TRP A 1 52 ? -48.522 -19.219 -20.887 1.00 100.65 ? 52 TRP A CE2 1 ATOM 394 C CE3 . TRP A 1 52 ? -47.635 -17.046 -20.277 1.00 99.97 ? 52 TRP A CE3 1 ATOM 395 C CZ2 . TRP A 1 52 ? -49.005 -19.433 -19.597 1.00 100.81 ? 52 TRP A CZ2 1 ATOM 396 C CZ3 . TRP A 1 52 ? -48.109 -17.261 -19.000 1.00 100.17 ? 52 TRP A CZ3 1 ATOM 397 C CH2 . TRP A 1 52 ? -48.790 -18.446 -18.670 1.00 100.77 ? 52 TRP A CH2 1 ATOM 398 N N . SER A 1 53 ? -48.076 -17.631 -26.271 1.00 101.92 ? 53 SER A N 1 ATOM 399 C CA . SER A 1 53 ? -48.794 -18.532 -27.161 1.00 102.03 ? 53 SER A CA 1 ATOM 400 C C . SER A 1 53 ? -48.349 -19.937 -26.786 1.00 101.90 ? 53 SER A C 1 ATOM 401 O O . SER A 1 53 ? -47.176 -20.146 -26.434 1.00 102.10 ? 53 SER A O 1 ATOM 402 C CB . SER A 1 53 ? -48.441 -18.221 -28.627 1.00 101.97 ? 53 SER A CB 1 ATOM 403 O OG . SER A 1 53 ? -49.424 -18.733 -29.503 1.00 101.82 ? 53 SER A OG 1 ATOM 404 N N . ASP A 1 54 ? -49.261 -20.901 -26.821 1.00 101.26 ? 54 ASP A N 1 ATOM 405 C CA . ASP A 1 54 ? -48.833 -22.259 -26.545 1.00 100.72 ? 54 ASP A CA 1 ATOM 406 C C . ASP A 1 54 ? -49.107 -22.713 -25.116 1.00 99.73 ? 54 ASP A C 1 ATOM 407 O O . ASP A 1 54 ? -49.841 -22.063 -24.366 1.00 99.94 ? 54 ASP A O 1 ATOM 408 C CB . ASP A 1 54 ? -47.327 -22.366 -26.781 1.00 101.17 ? 54 ASP A CB 1 ATOM 409 C CG . ASP A 1 54 ? -46.931 -23.657 -27.466 1.00 102.95 ? 54 ASP A CG 1 ATOM 410 O OD1 . ASP A 1 54 ? -47.430 -24.743 -27.072 1.00 104.71 ? 54 ASP A OD1 1 ATOM 411 O OD2 . ASP A 1 54 ? -46.107 -23.583 -28.408 1.00 105.04 ? 54 ASP A OD2 1 ATOM 412 N N . ILE A 1 55 ? -48.500 -23.840 -24.753 1.00 98.24 ? 55 ILE A N 1 ATOM 413 C CA . ILE A 1 55 ? -48.632 -24.392 -23.424 1.00 96.91 ? 55 ILE A CA 1 ATOM 414 C C . ILE A 1 55 ? -47.362 -24.145 -22.633 1.00 96.23 ? 55 ILE A C 1 ATOM 415 O O . ILE A 1 55 ? -46.258 -24.391 -23.123 1.00 96.24 ? 55 ILE A O 1 ATOM 416 C CB . ILE A 1 55 ? -48.905 -25.897 -23.459 1.00 96.77 ? 55 ILE A CB 1 ATOM 417 C CG1 . ILE A 1 55 ? -50.395 -26.140 -23.618 1.00 96.91 ? 55 ILE A CG1 1 ATOM 418 C CG2 . ILE A 1 55 ? -48.456 -26.552 -22.168 1.00 96.53 ? 55 ILE A CG2 1 ATOM 419 C CD1 . ILE A 1 55 ? -50.799 -27.578 -23.361 1.00 97.36 ? 55 ILE A CD1 1 ATOM 420 N N . TRP A 1 56 ? -47.518 -23.643 -21.411 1.00 95.07 ? 56 TRP A N 1 ATOM 421 C CA . TRP A 1 56 ? -46.409 -23.592 -20.480 1.00 93.60 ? 56 TRP A CA 1 ATOM 422 C C . TRP A 1 56 ? -46.390 -24.866 -19.632 1.00 93.43 ? 56 TRP A C 1 ATOM 423 O O . TRP A 1 56 ? -47.375 -25.186 -18.957 1.00 93.47 ? 56 TRP A O 1 ATOM 424 C CB . TRP A 1 56 ? -46.517 -22.366 -19.586 1.00 93.06 ? 56 TRP A CB 1 ATOM 425 C CG . TRP A 1 56 ? -45.387 -22.266 -18.633 1.00 90.61 ? 56 TRP A CG 1 ATOM 426 C CD1 . TRP A 1 56 ? -45.211 -22.988 -17.491 1.00 89.36 ? 56 TRP A CD1 1 ATOM 427 C CD2 . TRP A 1 56 ? -44.263 -21.401 -18.737 1.00 88.14 ? 56 TRP A CD2 1 ATOM 428 N NE1 . TRP A 1 56 ? -44.046 -22.621 -16.870 1.00 88.18 ? 56 TRP A NE1 1 ATOM 429 C CE2 . TRP A 1 56 ? -43.443 -21.647 -17.620 1.00 87.71 ? 56 TRP A CE2 1 ATOM 430 C CE3 . TRP A 1 56 ? -43.869 -20.437 -19.665 1.00 87.35 ? 56 TRP A CE3 1 ATOM 431 C CZ2 . TRP A 1 56 ? -42.250 -20.973 -17.413 1.00 87.10 ? 56 TRP A CZ2 1 ATOM 432 C CZ3 . TRP A 1 56 ? -42.690 -19.763 -19.456 1.00 86.91 ? 56 TRP A CZ3 1 ATOM 433 C CH2 . TRP A 1 56 ? -41.892 -20.032 -18.339 1.00 86.92 ? 56 TRP A CH2 1 ATOM 434 N N . ASN A 1 57 ? -45.284 -25.607 -19.693 1.00 92.86 ? 57 ASN A N 1 ATOM 435 C CA . ASN A 1 57 ? -45.082 -26.755 -18.807 1.00 92.38 ? 57 ASN A CA 1 ATOM 436 C C . ASN A 1 57 ? -44.700 -26.231 -17.406 1.00 91.01 ? 57 ASN A C 1 ATOM 437 O O . ASN A 1 57 ? -43.593 -25.751 -17.203 1.00 91.16 ? 57 ASN A O 1 ATOM 438 C CB . ASN A 1 57 ? -43.992 -27.706 -19.367 1.00 92.99 ? 57 ASN A CB 1 ATOM 439 C CG . ASN A 1 57 ? -44.415 -28.420 -20.670 1.00 95.59 ? 57 ASN A CG 1 ATOM 440 O OD1 . ASN A 1 57 ? -45.431 -28.074 -21.258 1.00 96.64 ? 57 ASN A OD1 1 ATOM 441 N ND2 . ASN A 1 57 ? -43.594 -29.398 -21.135 1.00 100.09 ? 57 ASN A ND2 1 ATOM 442 N N . ALA A 1 58 ? -45.601 -26.292 -16.439 1.00 89.19 ? 58 ALA A N 1 ATOM 443 C CA . ALA A 1 58 ? -45.262 -25.767 -15.126 1.00 87.56 ? 58 ALA A CA 1 ATOM 444 C C . ALA A 1 58 ? -44.975 -26.896 -14.159 1.00 86.45 ? 58 ALA A C 1 ATOM 445 O O . ALA A 1 58 ? -45.775 -27.149 -13.267 1.00 86.36 ? 58 ALA A O 1 ATOM 446 C CB . ALA A 1 58 ? -46.394 -24.907 -14.596 1.00 87.65 ? 58 ALA A CB 1 ATOM 447 N N . THR A 1 59 ? -43.834 -27.561 -14.311 1.00 84.91 ? 59 THR A N 1 ATOM 448 C CA . THR A 1 59 ? -43.594 -28.803 -13.568 1.00 83.66 ? 59 THR A CA 1 ATOM 449 C C . THR A 1 59 ? -42.286 -28.904 -12.814 1.00 82.46 ? 59 THR A C 1 ATOM 450 O O . THR A 1 59 ? -41.901 -29.975 -12.392 1.00 82.34 ? 59 THR A O 1 ATOM 451 C CB . THR A 1 59 ? -43.680 -30.013 -14.479 1.00 83.69 ? 59 THR A CB 1 ATOM 452 O OG1 . THR A 1 59 ? -43.181 -29.644 -15.761 1.00 84.65 ? 59 THR A OG1 1 ATOM 453 C CG2 . THR A 1 59 ? -45.110 -30.443 -14.644 1.00 83.51 ? 59 THR A CG2 1 ATOM 454 N N . LYS A 1 60 ? -41.604 -27.790 -12.648 1.00 81.24 ? 60 LYS A N 1 ATOM 455 C CA . LYS A 1 60 ? -40.494 -27.722 -11.720 1.00 79.90 ? 60 LYS A CA 1 ATOM 456 C C . LYS A 1 60 ? -40.483 -26.326 -11.110 1.00 78.88 ? 60 LYS A C 1 ATOM 457 O O . LYS A 1 60 ? -40.864 -25.352 -11.762 1.00 78.86 ? 60 LYS A O 1 ATOM 458 C CB . LYS A 1 60 ? -39.171 -27.993 -12.435 1.00 80.24 ? 60 LYS A CB 1 ATOM 459 C CG . LYS A 1 60 ? -38.960 -27.203 -13.751 1.00 80.95 ? 60 LYS A CG 1 ATOM 460 C CD . LYS A 1 60 ? -37.473 -27.091 -14.120 1.00 81.87 ? 60 LYS A CD 1 ATOM 461 C CE . LYS A 1 60 ? -36.759 -28.422 -13.858 1.00 83.31 ? 60 LYS A CE 1 ATOM 462 N NZ . LYS A 1 60 ? -35.307 -28.267 -13.520 1.00 83.76 ? 60 LYS A NZ 1 ATOM 463 N N . TYR A 1 61 ? -40.057 -26.222 -9.858 1.00 77.42 ? 61 TYR A N 1 ATOM 464 C CA . TYR A 1 61 ? -39.863 -24.922 -9.233 1.00 75.84 ? 61 TYR A CA 1 ATOM 465 C C . TYR A 1 61 ? -39.025 -24.033 -10.145 1.00 75.34 ? 61 TYR A C 1 ATOM 466 O O . TYR A 1 61 ? -38.152 -24.525 -10.829 1.00 75.53 ? 61 TYR A O 1 ATOM 467 C CB . TYR A 1 61 ? -39.139 -25.119 -7.920 1.00 75.35 ? 61 TYR A CB 1 ATOM 468 C CG . TYR A 1 61 ? -40.005 -25.627 -6.791 1.00 74.12 ? 61 TYR A CG 1 ATOM 469 C CD1 . TYR A 1 61 ? -41.134 -24.934 -6.389 1.00 73.72 ? 61 TYR A CD1 1 ATOM 470 C CD2 . TYR A 1 61 ? -39.670 -26.775 -6.088 1.00 72.75 ? 61 TYR A CD2 1 ATOM 471 C CE1 . TYR A 1 61 ? -41.913 -25.381 -5.327 1.00 72.30 ? 61 TYR A CE1 1 ATOM 472 C CE2 . TYR A 1 61 ? -40.453 -27.228 -5.016 1.00 70.76 ? 61 TYR A CE2 1 ATOM 473 C CZ . TYR A 1 61 ? -41.570 -26.525 -4.648 1.00 70.56 ? 61 TYR A CZ 1 ATOM 474 O OH . TYR A 1 61 ? -42.357 -26.941 -3.605 1.00 69.36 ? 61 TYR A OH 1 ATOM 475 N N . ALA A 1 62 ? -39.277 -22.731 -10.176 1.00 74.68 ? 62 ALA A N 1 ATOM 476 C CA . ALA A 1 62 ? -38.477 -21.852 -11.035 1.00 73.97 ? 62 ALA A CA 1 ATOM 477 C C . ALA A 1 62 ? -37.209 -21.364 -10.347 1.00 73.72 ? 62 ALA A C 1 ATOM 478 O O . ALA A 1 62 ? -36.905 -21.754 -9.226 1.00 73.41 ? 62 ALA A O 1 ATOM 479 C CB . ALA A 1 62 ? -39.292 -20.684 -11.491 1.00 73.87 ? 62 ALA A CB 1 ATOM 480 N N . ASN A 1 63 ? -36.467 -20.506 -11.030 1.00 73.60 ? 63 ASN A N 1 ATOM 481 C CA . ASN A 1 63 ? -35.270 -19.900 -10.453 1.00 73.55 ? 63 ASN A CA 1 ATOM 482 C C . ASN A 1 63 ? -35.566 -19.047 -9.230 1.00 73.13 ? 63 ASN A C 1 ATOM 483 O O . ASN A 1 63 ? -36.417 -18.178 -9.269 1.00 73.17 ? 63 ASN A O 1 ATOM 484 C CB . ASN A 1 63 ? -34.599 -18.985 -11.477 1.00 73.99 ? 63 ASN A CB 1 ATOM 485 C CG . ASN A 1 63 ? -33.998 -19.737 -12.625 1.00 74.86 ? 63 ASN A CG 1 ATOM 486 O OD1 . ASN A 1 63 ? -33.464 -20.821 -12.448 1.00 76.64 ? 63 ASN A OD1 1 ATOM 487 N ND2 . ASN A 1 63 ? -34.067 -19.161 -13.812 1.00 75.45 ? 63 ASN A ND2 1 ATOM 488 N N . SER A 1 64 ? -34.836 -19.262 -8.152 1.00 72.49 ? 64 SER A N 1 ATOM 489 C CA . SER A 1 64 ? -34.855 -18.338 -7.046 1.00 71.99 ? 64 SER A CA 1 ATOM 490 C C . SER A 1 64 ? -34.225 -17.026 -7.494 1.00 71.85 ? 64 SER A C 1 ATOM 491 O O . SER A 1 64 ? -33.596 -16.984 -8.530 1.00 72.06 ? 64 SER A O 1 ATOM 492 C CB . SER A 1 64 ? -34.068 -18.940 -5.906 1.00 72.10 ? 64 SER A CB 1 ATOM 493 O OG . SER A 1 64 ? -34.711 -20.122 -5.439 1.00 72.68 ? 64 SER A OG 1 ATOM 494 N N . CYS A 1 65 ? -34.399 -15.947 -6.742 1.00 71.77 ? 65 CYS A N 1 ATOM 495 C CA . CYS A 1 65 ? -33.822 -14.654 -7.132 1.00 71.64 ? 65 CYS A CA 1 ATOM 496 C C . CYS A 1 65 ? -32.440 -14.444 -6.528 1.00 71.69 ? 65 CYS A C 1 ATOM 497 O O . CYS A 1 65 ? -32.087 -15.083 -5.528 1.00 71.59 ? 65 CYS A O 1 ATOM 498 C CB . CYS A 1 65 ? -34.714 -13.504 -6.679 1.00 71.71 ? 65 CYS A CB 1 ATOM 499 S SG . CYS A 1 65 ? -36.384 -13.499 -7.337 1.00 71.43 ? 65 CYS A SG 1 ATOM 500 N N . CYS A 1 66 ? -31.675 -13.523 -7.105 1.00 71.36 ? 66 CYS A N 1 ATOM 501 C CA . CYS A 1 66 ? -30.311 -13.315 -6.650 1.00 71.64 ? 66 CYS A CA 1 ATOM 502 C C . CYS A 1 66 ? -30.262 -12.979 -5.185 1.00 71.17 ? 66 CYS A C 1 ATOM 503 O O . CYS A 1 66 ? -31.158 -12.336 -4.665 1.00 71.75 ? 66 CYS A O 1 ATOM 504 C CB . CYS A 1 66 ? -29.652 -12.222 -7.452 1.00 71.66 ? 66 CYS A CB 1 ATOM 505 S SG . CYS A 1 66 ? -29.407 -12.730 -9.144 1.00 74.97 ? 66 CYS A SG 1 ATOM 506 N N . GLN A 1 67 ? -29.208 -13.404 -4.512 1.00 70.55 ? 67 GLN A N 1 ATOM 507 C CA . GLN A 1 67 ? -29.116 -13.196 -3.088 1.00 69.99 ? 67 GLN A CA 1 ATOM 508 C C . GLN A 1 67 ? -27.830 -13.828 -2.600 1.00 70.00 ? 67 GLN A C 1 ATOM 509 O O . GLN A 1 67 ? -27.260 -14.642 -3.299 1.00 70.15 ? 67 GLN A O 1 ATOM 510 C CB . GLN A 1 67 ? -30.324 -13.840 -2.403 1.00 70.07 ? 67 GLN A CB 1 ATOM 511 C CG . GLN A 1 67 ? -30.700 -15.236 -2.914 1.00 68.65 ? 67 GLN A CG 1 ATOM 512 C CD . GLN A 1 67 ? -31.570 -16.034 -1.938 1.00 67.33 ? 67 GLN A CD 1 ATOM 513 O OE1 . GLN A 1 67 ? -31.090 -16.530 -0.914 1.00 66.09 ? 67 GLN A OE1 1 ATOM 514 N NE2 . GLN A 1 67 ? -32.845 -16.176 -2.266 1.00 65.00 ? 67 GLN A NE2 1 ATOM 515 N N . ASN A 1 68 ? -27.348 -13.449 -1.425 1.00 70.14 ? 68 ASN A N 1 ATOM 516 C CA . ASN A 1 68 ? -26.215 -14.154 -0.854 1.00 70.53 ? 68 ASN A CA 1 ATOM 517 C C . ASN A 1 68 ? -26.671 -15.395 -0.116 1.00 70.76 ? 68 ASN A C 1 ATOM 518 O O . ASN A 1 68 ? -27.851 -15.604 0.078 1.00 70.78 ? 68 ASN A O 1 ATOM 519 C CB . ASN A 1 68 ? -25.379 -13.245 0.033 1.00 70.52 ? 68 ASN A CB 1 ATOM 520 C CG . ASN A 1 68 ? -24.882 -12.030 -0.708 1.00 70.76 ? 68 ASN A CG 1 ATOM 521 O OD1 . ASN A 1 68 ? -24.777 -12.030 -1.930 1.00 70.48 ? 68 ASN A OD1 1 ATOM 522 N ND2 . ASN A 1 68 ? -24.603 -10.977 0.026 1.00 71.82 ? 68 ASN A ND2 1 ATOM 523 N N . ILE A 1 69 ? -25.734 -16.240 0.268 1.00 71.41 ? 69 ILE A N 1 ATOM 524 C CA . ILE A 1 69 ? -26.087 -17.519 0.834 1.00 72.40 ? 69 ILE A CA 1 ATOM 525 C C . ILE A 1 69 ? -25.402 -17.653 2.176 1.00 73.60 ? 69 ILE A C 1 ATOM 526 O O . ILE A 1 69 ? -24.222 -17.352 2.307 1.00 73.98 ? 69 ILE A O 1 ATOM 527 C CB . ILE A 1 69 ? -25.652 -18.671 -0.073 1.00 72.07 ? 69 ILE A CB 1 ATOM 528 C CG1 . ILE A 1 69 ? -26.749 -19.037 -1.054 1.00 72.26 ? 69 ILE A CG1 1 ATOM 529 C CG2 . ILE A 1 69 ? -25.351 -19.882 0.724 1.00 72.44 ? 69 ILE A CG2 1 ATOM 530 C CD1 . ILE A 1 69 ? -26.638 -18.299 -2.365 1.00 72.20 ? 69 ILE A CD1 1 ATOM 531 N N . ASP A 1 70 ? -26.140 -18.099 3.181 1.00 74.97 ? 70 ASP A N 1 ATOM 532 C CA . ASP A 1 70 ? -25.595 -18.220 4.510 1.00 76.51 ? 70 ASP A CA 1 ATOM 533 C C . ASP A 1 70 ? -24.617 -19.372 4.549 1.00 77.40 ? 70 ASP A C 1 ATOM 534 O O . ASP A 1 70 ? -24.994 -20.515 4.352 1.00 77.64 ? 70 ASP A O 1 ATOM 535 C CB . ASP A 1 70 ? -26.729 -18.431 5.512 1.00 76.83 ? 70 ASP A CB 1 ATOM 536 C CG . ASP A 1 70 ? -26.265 -19.086 6.790 1.00 77.69 ? 70 ASP A CG 1 ATOM 537 O OD1 . ASP A 1 70 ? -27.121 -19.584 7.559 1.00 78.24 ? 70 ASP A OD1 1 ATOM 538 O OD2 . ASP A 1 70 ? -25.037 -19.116 7.014 1.00 78.66 ? 70 ASP A OD2 1 ATOM 539 N N . GLN A 1 71 ? -23.351 -19.082 4.801 1.00 78.61 ? 71 GLN A N 1 ATOM 540 C CA . GLN A 1 71 ? -22.367 -20.147 4.804 1.00 80.06 ? 71 GLN A CA 1 ATOM 541 C C . GLN A 1 71 ? -21.568 -20.284 6.070 1.00 80.32 ? 71 GLN A C 1 ATOM 542 O O . GLN A 1 71 ? -20.468 -20.821 6.039 1.00 80.50 ? 71 GLN A O 1 ATOM 543 C CB . GLN A 1 71 ? -21.423 -20.003 3.633 1.00 80.41 ? 71 GLN A CB 1 ATOM 544 C CG . GLN A 1 71 ? -22.003 -20.559 2.387 1.00 82.98 ? 71 GLN A CG 1 ATOM 545 C CD . GLN A 1 71 ? -21.522 -19.817 1.181 1.00 86.35 ? 71 GLN A CD 1 ATOM 546 O OE1 . GLN A 1 71 ? -22.018 -20.033 0.070 1.00 88.33 ? 71 GLN A OE1 1 ATOM 547 N NE2 . GLN A 1 71 ? -20.548 -18.928 1.379 1.00 87.13 ? 71 GLN A NE2 1 ATOM 548 N N . SER A 1 72 ? -22.126 -19.807 7.177 1.00 80.72 ? 72 SER A N 1 ATOM 549 C CA . SER A 1 72 ? -21.577 -20.076 8.505 1.00 81.01 ? 72 SER A CA 1 ATOM 550 C C . SER A 1 72 ? -21.372 -21.570 8.775 1.00 81.18 ? 72 SER A C 1 ATOM 551 O O . SER A 1 72 ? -20.374 -21.961 9.351 1.00 81.19 ? 72 SER A O 1 ATOM 552 C CB . SER A 1 72 ? -22.491 -19.513 9.593 1.00 80.88 ? 72 SER A CB 1 ATOM 553 O OG . SER A 1 72 ? -22.555 -18.100 9.561 1.00 81.48 ? 72 SER A OG 1 ATOM 554 N N . PHE A 1 73 ? -22.310 -22.411 8.367 1.00 81.45 ? 73 PHE A N 1 ATOM 555 C CA . PHE A 1 73 ? -22.249 -23.800 8.779 1.00 81.87 ? 73 PHE A CA 1 ATOM 556 C C . PHE A 1 73 ? -22.435 -24.746 7.616 1.00 82.06 ? 73 PHE A C 1 ATOM 557 O O . PHE A 1 73 ? -23.483 -25.375 7.479 1.00 82.04 ? 73 PHE A O 1 ATOM 558 C CB . PHE A 1 73 ? -23.288 -24.064 9.868 1.00 82.21 ? 73 PHE A CB 1 ATOM 559 C CG . PHE A 1 73 ? -23.288 -23.024 10.967 1.00 82.44 ? 73 PHE A CG 1 ATOM 560 C CD1 . PHE A 1 73 ? -22.272 -22.986 11.901 1.00 82.02 ? 73 PHE A CD1 1 ATOM 561 C CD2 . PHE A 1 73 ? -24.297 -22.078 11.051 1.00 82.65 ? 73 PHE A CD2 1 ATOM 562 C CE1 . PHE A 1 73 ? -22.265 -22.029 12.901 1.00 81.89 ? 73 PHE A CE1 1 ATOM 563 C CE2 . PHE A 1 73 ? -24.290 -21.119 12.053 1.00 82.55 ? 73 PHE A CE2 1 ATOM 564 C CZ . PHE A 1 73 ? -23.272 -21.093 12.972 1.00 81.75 ? 73 PHE A CZ 1 ATOM 565 N N . PRO A 1 74 ? -21.392 -24.873 6.782 1.00 82.19 ? 74 PRO A N 1 ATOM 566 C CA . PRO A 1 74 ? -21.538 -25.638 5.564 1.00 81.73 ? 74 PRO A CA 1 ATOM 567 C C . PRO A 1 74 ? -21.865 -27.064 5.945 1.00 81.09 ? 74 PRO A C 1 ATOM 568 O O . PRO A 1 74 ? -21.297 -27.591 6.895 1.00 80.85 ? 74 PRO A O 1 ATOM 569 C CB . PRO A 1 74 ? -20.153 -25.535 4.915 1.00 81.78 ? 74 PRO A CB 1 ATOM 570 C CG . PRO A 1 74 ? -19.413 -24.472 5.671 1.00 82.01 ? 74 PRO A CG 1 ATOM 571 C CD . PRO A 1 74 ? -19.986 -24.508 7.035 1.00 82.22 ? 74 PRO A CD 1 ATOM 572 N N . GLY A 1 75 ? -22.811 -27.660 5.236 1.00 80.45 ? 75 GLY A N 1 ATOM 573 C CA . GLY A 1 75 ? -23.240 -29.015 5.533 1.00 80.09 ? 75 GLY A CA 1 ATOM 574 C C . GLY A 1 75 ? -24.283 -29.125 6.630 1.00 79.80 ? 75 GLY A C 1 ATOM 575 O O . GLY A 1 75 ? -24.975 -30.134 6.744 1.00 79.62 ? 75 GLY A O 1 ATOM 576 N N . PHE A 1 76 ? -24.409 -28.086 7.444 1.00 79.67 ? 76 PHE A N 1 ATOM 577 C CA . PHE A 1 76 ? -25.392 -28.121 8.517 1.00 79.22 ? 76 PHE A CA 1 ATOM 578 C C . PHE A 1 76 ? -26.788 -27.923 7.969 1.00 78.79 ? 76 PHE A C 1 ATOM 579 O O . PHE A 1 76 ? -27.063 -26.916 7.325 1.00 78.81 ? 76 PHE A O 1 ATOM 580 C CB . PHE A 1 76 ? -25.095 -27.061 9.565 1.00 79.22 ? 76 PHE A CB 1 ATOM 581 C CG . PHE A 1 76 ? -26.013 -27.113 10.744 1.00 79.81 ? 76 PHE A CG 1 ATOM 582 C CD1 . PHE A 1 76 ? -26.361 -28.321 11.313 1.00 79.51 ? 76 PHE A CD1 1 ATOM 583 C CD2 . PHE A 1 76 ? -26.516 -25.951 11.301 1.00 80.35 ? 76 PHE A CD2 1 ATOM 584 C CE1 . PHE A 1 76 ? -27.199 -28.370 12.404 1.00 79.95 ? 76 PHE A CE1 1 ATOM 585 C CE2 . PHE A 1 76 ? -27.357 -25.994 12.395 1.00 79.95 ? 76 PHE A CE2 1 ATOM 586 C CZ . PHE A 1 76 ? -27.694 -27.203 12.948 1.00 79.97 ? 76 PHE A CZ 1 ATOM 587 N N . HIS A 1 77 ? -27.675 -28.878 8.231 1.00 78.21 ? 77 HIS A N 1 ATOM 588 C CA . HIS A 1 77 ? -29.052 -28.759 7.782 1.00 77.61 ? 77 HIS A CA 1 ATOM 589 C C . HIS A 1 77 ? -29.677 -27.512 8.371 1.00 76.94 ? 77 HIS A C 1 ATOM 590 O O . HIS A 1 77 ? -30.222 -26.676 7.652 1.00 76.59 ? 77 HIS A O 1 ATOM 591 C CB . HIS A 1 77 ? -29.871 -29.975 8.196 1.00 77.76 ? 77 HIS A CB 1 ATOM 592 C CG . HIS A 1 77 ? -31.283 -29.940 7.694 1.00 78.78 ? 77 HIS A CG 1 ATOM 593 N ND1 . HIS A 1 77 ? -31.596 -29.718 6.366 1.00 79.40 ? 77 HIS A ND1 1 ATOM 594 C CD2 . HIS A 1 77 ? -32.465 -30.102 8.339 1.00 79.25 ? 77 HIS A CD2 1 ATOM 595 C CE1 . HIS A 1 77 ? -32.910 -29.730 6.218 1.00 79.47 ? 77 HIS A CE1 1 ATOM 596 N NE2 . HIS A 1 77 ? -33.460 -29.967 7.398 1.00 79.83 ? 77 HIS A NE2 1 ATOM 597 N N . GLY A 1 78 ? -29.581 -27.408 9.695 1.00 76.28 ? 78 GLY A N 1 ATOM 598 C CA . GLY A 1 78 ? -30.113 -26.293 10.467 1.00 75.05 ? 78 GLY A CA 1 ATOM 599 C C . GLY A 1 78 ? -30.021 -24.928 9.828 1.00 74.41 ? 78 GLY A C 1 ATOM 600 O O . GLY A 1 78 ? -30.968 -24.155 9.909 1.00 74.03 ? 78 GLY A O 1 ATOM 601 N N . SER A 1 79 ? -28.886 -24.616 9.206 1.00 73.89 ? 79 SER A N 1 ATOM 602 C CA . SER A 1 79 ? -28.716 -23.327 8.564 1.00 73.45 ? 79 SER A CA 1 ATOM 603 C C . SER A 1 79 ? -28.992 -23.406 7.088 1.00 73.05 ? 79 SER A C 1 ATOM 604 O O . SER A 1 79 ? -29.480 -22.450 6.505 1.00 72.74 ? 79 SER A O 1 ATOM 605 C CB . SER A 1 79 ? -27.308 -22.789 8.783 1.00 73.59 ? 79 SER A CB 1 ATOM 606 O OG . SER A 1 79 ? -26.434 -23.265 7.787 1.00 74.22 ? 79 SER A OG 1 ATOM 607 N N . GLU A 1 80 ? -28.679 -24.548 6.486 1.00 72.98 ? 80 GLU A N 1 ATOM 608 C CA . GLU A 1 80 ? -28.755 -24.687 5.028 1.00 72.89 ? 80 GLU A CA 1 ATOM 609 C C . GLU A 1 80 ? -30.158 -24.911 4.485 1.00 72.11 ? 80 GLU A C 1 ATOM 610 O O . GLU A 1 80 ? -30.443 -24.557 3.348 1.00 71.79 ? 80 GLU A O 1 ATOM 611 C CB . GLU A 1 80 ? -27.784 -25.748 4.515 1.00 73.25 ? 80 GLU A CB 1 ATOM 612 C CG . GLU A 1 80 ? -26.378 -25.211 4.347 1.00 75.71 ? 80 GLU A CG 1 ATOM 613 C CD . GLU A 1 80 ? -25.387 -26.273 3.966 1.00 78.58 ? 80 GLU A CD 1 ATOM 614 O OE1 . GLU A 1 80 ? -24.515 -25.998 3.113 1.00 79.64 ? 80 GLU A OE1 1 ATOM 615 O OE2 . GLU A 1 80 ? -25.485 -27.385 4.522 1.00 80.20 ? 80 GLU A OE2 1 ATOM 616 N N . MET A 1 81 ? -31.029 -25.490 5.305 1.00 71.34 ? 81 MET A N 1 ATOM 617 C CA . MET A 1 81 ? -32.414 -25.701 4.918 1.00 70.33 ? 81 MET A CA 1 ATOM 618 C C . MET A 1 81 ? -33.071 -24.400 4.484 1.00 69.86 ? 81 MET A C 1 ATOM 619 O O . MET A 1 81 ? -34.133 -24.406 3.886 1.00 70.03 ? 81 MET A O 1 ATOM 620 C CB . MET A 1 81 ? -33.210 -26.322 6.070 1.00 70.10 ? 81 MET A CB 1 ATOM 621 C CG . MET A 1 81 ? -33.644 -25.339 7.130 1.00 69.22 ? 81 MET A CG 1 ATOM 622 S SD . MET A 1 81 ? -34.524 -26.075 8.531 1.00 69.00 ? 81 MET A SD 1 ATOM 623 C CE . MET A 1 81 ? -36.161 -26.277 7.875 1.00 68.89 ? 81 MET A CE 1 ATOM 624 N N . TRP A 1 82 ? -32.453 -23.274 4.795 1.00 69.11 ? 82 TRP A N 1 ATOM 625 C CA . TRP A 1 82 ? -33.050 -22.018 4.427 1.00 68.01 ? 82 TRP A CA 1 ATOM 626 C C . TRP A 1 82 ? -32.444 -21.475 3.170 1.00 68.08 ? 82 TRP A C 1 ATOM 627 O O . TRP A 1 82 ? -33.017 -20.598 2.585 1.00 68.68 ? 82 TRP A O 1 ATOM 628 C CB . TRP A 1 82 ? -32.968 -20.991 5.559 1.00 67.55 ? 82 TRP A CB 1 ATOM 629 C CG . TRP A 1 82 ? -33.537 -21.477 6.852 1.00 65.18 ? 82 TRP A CG 1 ATOM 630 C CD1 . TRP A 1 82 ? -32.845 -21.957 7.898 1.00 64.76 ? 82 TRP A CD1 1 ATOM 631 C CD2 . TRP A 1 82 ? -34.921 -21.553 7.222 1.00 63.63 ? 82 TRP A CD2 1 ATOM 632 N NE1 . TRP A 1 82 ? -33.695 -22.325 8.919 1.00 63.99 ? 82 TRP A NE1 1 ATOM 633 C CE2 . TRP A 1 82 ? -34.979 -22.089 8.522 1.00 63.51 ? 82 TRP A CE2 1 ATOM 634 C CE3 . TRP A 1 82 ? -36.116 -21.224 6.581 1.00 62.24 ? 82 TRP A CE3 1 ATOM 635 C CZ2 . TRP A 1 82 ? -36.180 -22.293 9.198 1.00 62.63 ? 82 TRP A CZ2 1 ATOM 636 C CZ3 . TRP A 1 82 ? -37.309 -21.436 7.250 1.00 61.68 ? 82 TRP A CZ3 1 ATOM 637 C CH2 . TRP A 1 82 ? -37.332 -21.962 8.543 1.00 62.55 ? 82 TRP A CH2 1 ATOM 638 N N . ASN A 1 83 ? -31.296 -21.988 2.742 1.00 68.11 ? 83 ASN A N 1 ATOM 639 C CA . ASN A 1 83 ? -30.668 -21.531 1.491 1.00 68.07 ? 83 ASN A CA 1 ATOM 640 C C . ASN A 1 83 ? -31.475 -21.894 0.242 1.00 68.05 ? 83 ASN A C 1 ATOM 641 O O . ASN A 1 83 ? -32.142 -22.924 0.214 1.00 68.18 ? 83 ASN A O 1 ATOM 642 C CB . ASN A 1 83 ? -29.269 -22.126 1.351 1.00 68.31 ? 83 ASN A CB 1 ATOM 643 C CG . ASN A 1 83 ? -28.259 -21.504 2.294 1.00 68.16 ? 83 ASN A CG 1 ATOM 644 O OD1 . ASN A 1 83 ? -27.995 -20.314 2.247 1.00 68.44 ? 83 ASN A OD1 1 ATOM 645 N ND2 . ASN A 1 83 ? -27.666 -22.325 3.128 1.00 67.67 ? 83 ASN A ND2 1 ATOM 646 N N . PRO A 1 84 ? -31.384 -21.075 -0.820 1.00 68.02 ? 84 PRO A N 1 ATOM 647 C CA . PRO A 1 84 ? -32.186 -21.356 -2.020 1.00 68.16 ? 84 PRO A CA 1 ATOM 648 C C . PRO A 1 84 ? -31.897 -22.742 -2.599 1.00 68.46 ? 84 PRO A C 1 ATOM 649 O O . PRO A 1 84 ? -30.753 -23.163 -2.637 1.00 68.56 ? 84 PRO A O 1 ATOM 650 C CB . PRO A 1 84 ? -31.769 -20.270 -3.017 1.00 67.62 ? 84 PRO A CB 1 ATOM 651 C CG . PRO A 1 84 ? -30.687 -19.506 -2.397 1.00 67.50 ? 84 PRO A CG 1 ATOM 652 C CD . PRO A 1 84 ? -30.382 -20.021 -1.034 1.00 68.03 ? 84 PRO A CD 1 ATOM 653 N N . ASN A 1 85 ? -32.932 -23.452 -3.028 1.00 68.85 ? 85 ASN A N 1 ATOM 654 C CA . ASN A 1 85 ? -32.728 -24.720 -3.688 1.00 68.98 ? 85 ASN A CA 1 ATOM 655 C C . ASN A 1 85 ? -33.073 -24.707 -5.178 1.00 69.56 ? 85 ASN A C 1 ATOM 656 O O . ASN A 1 85 ? -33.459 -25.723 -5.735 1.00 70.00 ? 85 ASN A O 1 ATOM 657 C CB . ASN A 1 85 ? -33.447 -25.850 -2.957 1.00 68.69 ? 85 ASN A CB 1 ATOM 658 C CG . ASN A 1 85 ? -34.929 -25.601 -2.789 1.00 68.44 ? 85 ASN A CG 1 ATOM 659 O OD1 . ASN A 1 85 ? -35.508 -24.690 -3.390 1.00 66.90 ? 85 ASN A OD1 1 ATOM 660 N ND2 . ASN A 1 85 ? -35.559 -26.429 -1.957 1.00 69.03 ? 85 ASN A ND2 1 ATOM 661 N N . THR A 1 86 ? -32.917 -23.570 -5.841 1.00 69.77 ? 86 THR A N 1 ATOM 662 C CA . THR A 1 86 ? -32.869 -23.598 -7.294 1.00 70.44 ? 86 THR A CA 1 ATOM 663 C C . THR A 1 86 ? -31.886 -22.541 -7.794 1.00 71.00 ? 86 THR A C 1 ATOM 664 O O . THR A 1 86 ? -31.411 -21.731 -7.016 1.00 71.24 ? 86 THR A O 1 ATOM 665 C CB . THR A 1 86 ? -34.243 -23.412 -7.894 1.00 70.27 ? 86 THR A CB 1 ATOM 666 O OG1 . THR A 1 86 ? -34.512 -22.020 -8.040 1.00 71.63 ? 86 THR A OG1 1 ATOM 667 C CG2 . THR A 1 86 ? -35.260 -24.001 -6.995 1.00 70.13 ? 86 THR A CG2 1 ATOM 668 N N . ASP A 1 87 ? -31.557 -22.538 -9.074 1.00 71.54 ? 87 ASP A N 1 ATOM 669 C CA . ASP A 1 87 ? -30.630 -21.531 -9.589 1.00 72.45 ? 87 ASP A CA 1 ATOM 670 C C . ASP A 1 87 ? -31.014 -20.093 -9.278 1.00 72.21 ? 87 ASP A C 1 ATOM 671 O O . ASP A 1 87 ? -32.065 -19.628 -9.686 1.00 72.45 ? 87 ASP A O 1 ATOM 672 C CB . ASP A 1 87 ? -30.498 -21.635 -11.113 1.00 73.26 ? 87 ASP A CB 1 ATOM 673 C CG . ASP A 1 87 ? -29.482 -22.655 -11.547 1.00 75.46 ? 87 ASP A CG 1 ATOM 674 O OD1 . ASP A 1 87 ? -29.776 -23.869 -11.426 1.00 78.59 ? 87 ASP A OD1 1 ATOM 675 O OD2 . ASP A 1 87 ? -28.400 -22.237 -12.013 1.00 76.45 ? 87 ASP A OD2 1 ATOM 676 N N . LEU A 1 88 ? -30.128 -19.369 -8.613 1.00 72.03 ? 88 LEU A N 1 ATOM 677 C CA . LEU A 1 88 ? -30.264 -17.930 -8.499 1.00 71.71 ? 88 LEU A CA 1 ATOM 678 C C . LEU A 1 88 ? -30.259 -17.323 -9.866 1.00 71.69 ? 88 LEU A C 1 ATOM 679 O O . LEU A 1 88 ? -29.486 -17.712 -10.713 1.00 71.93 ? 88 LEU A O 1 ATOM 680 C CB . LEU A 1 88 ? -29.080 -17.337 -7.757 1.00 71.70 ? 88 LEU A CB 1 ATOM 681 C CG . LEU A 1 88 ? -28.767 -17.960 -6.417 1.00 71.08 ? 88 LEU A CG 1 ATOM 682 C CD1 . LEU A 1 88 ? -27.998 -16.946 -5.587 1.00 70.63 ? 88 LEU A CD1 1 ATOM 683 C CD2 . LEU A 1 88 ? -30.078 -18.375 -5.764 1.00 70.62 ? 88 LEU A CD2 1 ATOM 684 N N . SER A 1 89 ? -31.088 -16.323 -10.070 1.00 72.01 ? 89 SER A N 1 ATOM 685 C CA . SER A 1 89 ? -31.173 -15.679 -11.357 1.00 72.33 ? 89 SER A CA 1 ATOM 686 C C . SER A 1 89 ? -31.842 -14.333 -11.213 1.00 72.52 ? 89 SER A C 1 ATOM 687 O O . SER A 1 89 ? -32.678 -14.140 -10.344 1.00 72.77 ? 89 SER A O 1 ATOM 688 C CB . SER A 1 89 ? -32.004 -16.539 -12.294 1.00 72.14 ? 89 SER A CB 1 ATOM 689 O OG . SER A 1 89 ? -32.219 -15.861 -13.505 1.00 72.28 ? 89 SER A OG 1 ATOM 690 N N . GLU A 1 90 ? -31.474 -13.389 -12.059 1.00 72.88 ? 90 GLU A N 1 ATOM 691 C CA . GLU A 1 90 ? -32.260 -12.171 -12.150 1.00 73.41 ? 90 GLU A CA 1 ATOM 692 C C . GLU A 1 90 ? -33.646 -12.506 -12.678 1.00 73.26 ? 90 GLU A C 1 ATOM 693 O O . GLU A 1 90 ? -34.590 -11.745 -12.502 1.00 73.70 ? 90 GLU A O 1 ATOM 694 C CB . GLU A 1 90 ? -31.598 -11.146 -13.067 1.00 73.42 ? 90 GLU A CB 1 ATOM 695 C CG . GLU A 1 90 ? -30.517 -10.364 -12.377 1.00 75.07 ? 90 GLU A CG 1 ATOM 696 C CD . GLU A 1 90 ? -30.306 -9.004 -12.997 1.00 77.63 ? 90 GLU A CD 1 ATOM 697 O OE1 . GLU A 1 90 ? -29.480 -8.883 -13.931 1.00 78.66 ? 90 GLU A OE1 1 ATOM 698 O OE2 . GLU A 1 90 ? -30.962 -8.047 -12.532 1.00 78.69 ? 90 GLU A OE2 1 ATOM 699 N N . ASP A 1 91 ? -33.768 -13.652 -13.327 1.00 72.90 ? 91 ASP A N 1 ATOM 700 C CA . ASP A 1 91 ? -35.031 -14.025 -13.940 1.00 72.54 ? 91 ASP A CA 1 ATOM 701 C C . ASP A 1 91 ? -35.767 -14.945 -12.984 1.00 72.23 ? 91 ASP A C 1 ATOM 702 O O . ASP A 1 91 ? -35.536 -16.153 -13.001 1.00 72.46 ? 91 ASP A O 1 ATOM 703 C CB . ASP A 1 91 ? -34.781 -14.724 -15.285 1.00 72.37 ? 91 ASP A CB 1 ATOM 704 C CG . ASP A 1 91 ? -36.041 -15.210 -15.922 1.00 71.91 ? 91 ASP A CG 1 ATOM 705 O OD1 . ASP A 1 91 ? -36.956 -15.613 -15.206 1.00 72.99 ? 91 ASP A OD1 1 ATOM 706 O OD2 . ASP A 1 91 ? -36.145 -15.192 -17.139 1.00 71.98 ? 91 ASP A OD2 1 ATOM 707 N N . CYS A 1 92 ? -36.656 -14.396 -12.159 1.00 71.41 ? 92 CYS A N 1 ATOM 708 C CA . CYS A 1 92 ? -37.191 -15.195 -11.067 1.00 70.78 ? 92 CYS A CA 1 ATOM 709 C C . CYS A 1 92 ? -38.641 -14.912 -10.663 1.00 70.10 ? 92 CYS A C 1 ATOM 710 O O . CYS A 1 92 ? -39.113 -15.374 -9.626 1.00 70.16 ? 92 CYS A O 1 ATOM 711 C CB . CYS A 1 92 ? -36.280 -15.044 -9.860 1.00 70.88 ? 92 CYS A CB 1 ATOM 712 S SG . CYS A 1 92 ? -36.147 -13.362 -9.336 1.00 71.29 ? 92 CYS A SG 1 ATOM 713 N N . LEU A 1 93 ? -39.361 -14.164 -11.478 1.00 69.21 ? 93 LEU A N 1 ATOM 714 C CA . LEU A 1 93 ? -40.727 -13.829 -11.117 1.00 68.23 ? 93 LEU A CA 1 ATOM 715 C C . LEU A 1 93 ? -41.702 -14.909 -11.550 1.00 67.98 ? 93 LEU A C 1 ATOM 716 O O . LEU A 1 93 ? -42.428 -14.761 -12.527 1.00 67.82 ? 93 LEU A O 1 ATOM 717 C CB . LEU A 1 93 ? -41.123 -12.471 -11.689 1.00 67.86 ? 93 LEU A CB 1 ATOM 718 C CG . LEU A 1 93 ? -40.188 -11.325 -11.301 1.00 67.30 ? 93 LEU A CG 1 ATOM 719 C CD1 . LEU A 1 93 ? -40.932 -10.051 -11.429 1.00 67.75 ? 93 LEU A CD1 1 ATOM 720 C CD2 . LEU A 1 93 ? -39.675 -11.432 -9.886 1.00 66.59 ? 93 LEU A CD2 1 ATOM 721 N N . TYR A 1 94 ? -41.703 -16.001 -10.812 1.00 67.72 ? 94 TYR A N 1 ATOM 722 C CA . TYR A 1 94 ? -42.659 -17.059 -11.034 1.00 68.13 ? 94 TYR A CA 1 ATOM 723 C C . TYR A 1 94 ? -43.388 -17.363 -9.738 1.00 68.02 ? 94 TYR A C 1 ATOM 724 O O . TYR A 1 94 ? -42.989 -16.890 -8.672 1.00 68.43 ? 94 TYR A O 1 ATOM 725 C CB . TYR A 1 94 ? -41.941 -18.301 -11.559 1.00 68.36 ? 94 TYR A CB 1 ATOM 726 C CG . TYR A 1 94 ? -41.088 -17.966 -12.751 1.00 69.62 ? 94 TYR A CG 1 ATOM 727 C CD1 . TYR A 1 94 ? -39.859 -17.351 -12.589 1.00 70.07 ? 94 TYR A CD1 1 ATOM 728 C CD2 . TYR A 1 94 ? -41.526 -18.226 -14.043 1.00 70.41 ? 94 TYR A CD2 1 ATOM 729 C CE1 . TYR A 1 94 ? -39.082 -17.018 -13.673 1.00 70.49 ? 94 TYR A CE1 1 ATOM 730 C CE2 . TYR A 1 94 ? -40.754 -17.893 -15.138 1.00 70.48 ? 94 TYR A CE2 1 ATOM 731 C CZ . TYR A 1 94 ? -39.536 -17.288 -14.946 1.00 70.77 ? 94 TYR A CZ 1 ATOM 732 O OH . TYR A 1 94 ? -38.764 -16.944 -16.028 1.00 71.37 ? 94 TYR A OH 1 ATOM 733 N N . LEU A 1 95 ? -44.455 -18.153 -9.820 1.00 67.58 ? 95 LEU A N 1 ATOM 734 C CA . LEU A 1 95 ? -45.231 -18.499 -8.630 1.00 66.96 ? 95 LEU A CA 1 ATOM 735 C C . LEU A 1 95 ? -45.785 -19.925 -8.711 1.00 66.66 ? 95 LEU A C 1 ATOM 736 O O . LEU A 1 95 ? -45.901 -20.482 -9.782 1.00 66.37 ? 95 LEU A O 1 ATOM 737 C CB . LEU A 1 95 ? -46.352 -17.476 -8.421 1.00 66.65 ? 95 LEU A CB 1 ATOM 738 C CG . LEU A 1 95 ? -47.253 -17.232 -9.628 1.00 66.01 ? 95 LEU A CG 1 ATOM 739 C CD1 . LEU A 1 95 ? -48.150 -18.410 -9.806 1.00 65.63 ? 95 LEU A CD1 1 ATOM 740 C CD2 . LEU A 1 95 ? -48.088 -15.991 -9.462 1.00 65.48 ? 95 LEU A CD2 1 ATOM 741 N N . ASN A 1 96 ? -46.115 -20.515 -7.574 1.00 66.51 ? 96 ASN A N 1 ATOM 742 C CA . ASN A 1 96 ? -46.657 -21.854 -7.563 1.00 66.47 ? 96 ASN A CA 1 ATOM 743 C C . ASN A 1 96 ? -48.096 -21.877 -7.101 1.00 66.68 ? 96 ASN A C 1 ATOM 744 O O . ASN A 1 96 ? -48.533 -21.010 -6.340 1.00 66.59 ? 96 ASN A O 1 ATOM 745 C CB . ASN A 1 96 ? -45.820 -22.702 -6.644 1.00 66.30 ? 96 ASN A CB 1 ATOM 746 C CG . ASN A 1 96 ? -44.378 -22.302 -6.681 1.00 66.48 ? 96 ASN A CG 1 ATOM 747 O OD1 . ASN A 1 96 ? -43.710 -22.441 -7.696 1.00 66.77 ? 96 ASN A OD1 1 ATOM 748 N ND2 . ASN A 1 96 ? -43.888 -21.785 -5.581 1.00 66.51 ? 96 ASN A ND2 1 ATOM 749 N N . VAL A 1 97 ? -48.836 -22.870 -7.582 1.00 66.78 ? 97 VAL A N 1 ATOM 750 C CA . VAL A 1 97 ? -50.206 -23.085 -7.164 1.00 66.59 ? 97 VAL A CA 1 ATOM 751 C C . VAL A 1 97 ? -50.342 -24.548 -6.882 1.00 67.03 ? 97 VAL A C 1 ATOM 752 O O . VAL A 1 97 ? -49.840 -25.348 -7.637 1.00 67.25 ? 97 VAL A O 1 ATOM 753 C CB . VAL A 1 97 ? -51.187 -22.786 -8.274 1.00 66.42 ? 97 VAL A CB 1 ATOM 754 C CG1 . VAL A 1 97 ? -52.570 -23.236 -7.864 1.00 66.36 ? 97 VAL A CG1 1 ATOM 755 C CG2 . VAL A 1 97 ? -51.183 -21.324 -8.615 1.00 65.92 ? 97 VAL A CG2 1 ATOM 756 N N . TRP A 1 98 ? -51.003 -24.900 -5.785 1.00 67.90 ? 98 TRP A N 1 ATOM 757 C CA . TRP A 1 98 ? -51.333 -26.284 -5.477 1.00 68.64 ? 98 TRP A CA 1 ATOM 758 C C . TRP A 1 98 ? -52.831 -26.347 -5.302 1.00 69.48 ? 98 TRP A C 1 ATOM 759 O O . TRP A 1 98 ? -53.339 -25.866 -4.305 1.00 69.86 ? 98 TRP A O 1 ATOM 760 C CB . TRP A 1 98 ? -50.700 -26.731 -4.164 1.00 68.24 ? 98 TRP A CB 1 ATOM 761 C CG . TRP A 1 98 ? -49.212 -26.963 -4.156 1.00 67.94 ? 98 TRP A CG 1 ATOM 762 C CD1 . TRP A 1 98 ? -48.564 -28.148 -4.348 1.00 67.55 ? 98 TRP A CD1 1 ATOM 763 C CD2 . TRP A 1 98 ? -48.192 -25.997 -3.864 1.00 67.72 ? 98 TRP A CD2 1 ATOM 764 N NE1 . TRP A 1 98 ? -47.203 -27.976 -4.231 1.00 67.59 ? 98 TRP A NE1 1 ATOM 765 C CE2 . TRP A 1 98 ? -46.947 -26.665 -3.935 1.00 67.26 ? 98 TRP A CE2 1 ATOM 766 C CE3 . TRP A 1 98 ? -48.208 -24.628 -3.560 1.00 66.62 ? 98 TRP A CE3 1 ATOM 767 C CZ2 . TRP A 1 98 ? -45.737 -26.014 -3.713 1.00 66.98 ? 98 TRP A CZ2 1 ATOM 768 C CZ3 . TRP A 1 98 ? -47.005 -23.988 -3.348 1.00 65.97 ? 98 TRP A CZ3 1 ATOM 769 C CH2 . TRP A 1 98 ? -45.786 -24.682 -3.418 1.00 66.20 ? 98 TRP A CH2 1 ATOM 770 N N . ILE A 1 99 ? -53.543 -26.923 -6.260 1.00 70.58 ? 99 ILE A N 1 ATOM 771 C CA . ILE A 1 99 ? -54.974 -27.111 -6.102 1.00 71.60 ? 99 ILE A CA 1 ATOM 772 C C . ILE A 1 99 ? -55.214 -28.558 -5.712 1.00 72.22 ? 99 ILE A C 1 ATOM 773 O O . ILE A 1 99 ? -54.526 -29.441 -6.193 1.00 72.42 ? 99 ILE A O 1 ATOM 774 C CB . ILE A 1 99 ? -55.694 -26.781 -7.391 1.00 71.66 ? 99 ILE A CB 1 ATOM 775 C CG1 . ILE A 1 99 ? -55.257 -27.742 -8.475 1.00 72.16 ? 99 ILE A CG1 1 ATOM 776 C CG2 . ILE A 1 99 ? -55.319 -25.385 -7.843 1.00 71.65 ? 99 ILE A CG2 1 ATOM 777 C CD1 . ILE A 1 99 ? -56.398 -28.473 -9.076 1.00 74.19 ? 99 ILE A CD1 1 ATOM 778 N N . PRO A 1 100 ? -56.164 -28.814 -4.808 1.00 73.01 ? 100 PRO A N 1 ATOM 779 C CA . PRO A 1 100 ? -56.345 -30.207 -4.442 1.00 73.66 ? 100 PRO A CA 1 ATOM 780 C C . PRO A 1 100 ? -57.069 -30.921 -5.579 1.00 74.51 ? 100 PRO A C 1 ATOM 781 O O . PRO A 1 100 ? -57.670 -30.258 -6.433 1.00 74.93 ? 100 PRO A O 1 ATOM 782 C CB . PRO A 1 100 ? -57.235 -30.126 -3.197 1.00 73.48 ? 100 PRO A CB 1 ATOM 783 C CG . PRO A 1 100 ? -58.002 -28.877 -3.336 1.00 73.01 ? 100 PRO A CG 1 ATOM 784 C CD . PRO A 1 100 ? -57.225 -27.952 -4.262 1.00 73.20 ? 100 PRO A CD 1 ATOM 785 N N . ALA A 1 101 ? -56.999 -32.247 -5.621 1.00 74.95 ? 101 ALA A N 1 ATOM 786 C CA . ALA A 1 101 ? -57.720 -32.984 -6.646 1.00 75.39 ? 101 ALA A CA 1 ATOM 787 C C . ALA A 1 101 ? -58.737 -33.886 -5.968 1.00 75.77 ? 101 ALA A C 1 ATOM 788 O O . ALA A 1 101 ? -58.411 -34.572 -5.012 1.00 75.99 ? 101 ALA A O 1 ATOM 789 C CB . ALA A 1 101 ? -56.756 -33.789 -7.516 1.00 75.42 ? 101 ALA A CB 1 ATOM 790 N N . PRO A 1 102 ? -59.974 -33.911 -6.479 1.00 76.12 ? 102 PRO A N 1 ATOM 791 C CA . PRO A 1 102 ? -60.410 -33.298 -7.746 1.00 76.38 ? 102 PRO A CA 1 ATOM 792 C C . PRO A 1 102 ? -60.568 -31.786 -7.678 1.00 76.51 ? 102 PRO A C 1 ATOM 793 O O . PRO A 1 102 ? -60.971 -31.260 -6.642 1.00 76.63 ? 102 PRO A O 1 ATOM 794 C CB . PRO A 1 102 ? -61.780 -33.938 -8.004 1.00 76.21 ? 102 PRO A CB 1 ATOM 795 C CG . PRO A 1 102 ? -61.983 -34.950 -6.892 1.00 76.57 ? 102 PRO A CG 1 ATOM 796 C CD . PRO A 1 102 ? -61.077 -34.572 -5.772 1.00 76.02 ? 102 PRO A CD 1 ATOM 797 N N . LYS A 1 103 ? -60.255 -31.109 -8.779 1.00 76.50 ? 103 LYS A N 1 ATOM 798 C CA . LYS A 1 103 ? -60.400 -29.666 -8.893 1.00 76.60 ? 103 LYS A CA 1 ATOM 799 C C . LYS A 1 103 ? -61.628 -29.198 -8.122 1.00 77.01 ? 103 LYS A C 1 ATOM 800 O O . LYS A 1 103 ? -62.722 -29.688 -8.372 1.00 76.82 ? 103 LYS A O 1 ATOM 801 C CB . LYS A 1 103 ? -60.537 -29.294 -10.360 1.00 76.48 ? 103 LYS A CB 1 ATOM 802 C CG . LYS A 1 103 ? -60.516 -27.832 -10.670 1.00 75.96 ? 103 LYS A CG 1 ATOM 803 C CD . LYS A 1 103 ? -60.826 -27.654 -12.140 1.00 75.25 ? 103 LYS A CD 1 ATOM 804 C CE . LYS A 1 103 ? -60.254 -26.369 -12.673 1.00 75.13 ? 103 LYS A CE 1 ATOM 805 N NZ . LYS A 1 103 ? -61.192 -25.238 -12.458 1.00 75.54 ? 103 LYS A NZ 1 ATOM 806 N N . PRO A 1 104 ? -61.447 -28.239 -7.180 1.00 77.37 ? 104 PRO A N 1 ATOM 807 C CA . PRO A 1 104 ? -62.521 -27.861 -6.289 1.00 77.16 ? 104 PRO A CA 1 ATOM 808 C C . PRO A 1 104 ? -63.321 -26.755 -6.923 1.00 77.21 ? 104 PRO A C 1 ATOM 809 O O . PRO A 1 104 ? -62.884 -26.169 -7.907 1.00 77.30 ? 104 PRO A O 1 ATOM 810 C CB . PRO A 1 104 ? -61.775 -27.334 -5.073 1.00 77.07 ? 104 PRO A CB 1 ATOM 811 C CG . PRO A 1 104 ? -60.527 -26.751 -5.621 1.00 77.07 ? 104 PRO A CG 1 ATOM 812 C CD . PRO A 1 104 ? -60.262 -27.381 -6.967 1.00 77.49 ? 104 PRO A CD 1 ATOM 813 N N . LYS A 1 105 ? -64.488 -26.475 -6.365 1.00 77.32 ? 105 LYS A N 1 ATOM 814 C CA . LYS A 1 105 ? -65.405 -25.538 -6.982 1.00 77.67 ? 105 LYS A CA 1 ATOM 815 C C . LYS A 1 105 ? -65.021 -24.110 -6.688 1.00 77.69 ? 105 LYS A C 1 ATOM 816 O O . LYS A 1 105 ? -64.754 -23.322 -7.614 1.00 77.72 ? 105 LYS A O 1 ATOM 817 C CB . LYS A 1 105 ? -66.814 -25.780 -6.466 1.00 77.82 ? 105 LYS A CB 1 ATOM 818 C CG . LYS A 1 105 ? -67.406 -27.127 -6.868 1.00 78.92 ? 105 LYS A CG 1 ATOM 819 C CD . LYS A 1 105 ? -67.833 -27.153 -8.331 1.00 80.02 ? 105 LYS A CD 1 ATOM 820 C CE . LYS A 1 105 ? -68.768 -28.306 -8.564 1.00 80.69 ? 105 LYS A CE 1 ATOM 821 N NZ . LYS A 1 105 ? -68.329 -29.066 -9.759 1.00 82.19 ? 105 LYS A NZ 1 ATOM 822 N N . ASN A 1 106 ? -64.991 -23.785 -5.394 1.00 77.43 ? 106 ASN A N 1 ATOM 823 C CA . ASN A 1 106 ? -64.793 -22.421 -4.959 1.00 77.23 ? 106 ASN A CA 1 ATOM 824 C C . ASN A 1 106 ? -63.831 -22.282 -3.784 1.00 76.12 ? 106 ASN A C 1 ATOM 825 O O . ASN A 1 106 ? -64.093 -21.514 -2.866 1.00 76.47 ? 106 ASN A O 1 ATOM 826 C CB . ASN A 1 106 ? -66.139 -21.821 -4.593 1.00 77.83 ? 106 ASN A CB 1 ATOM 827 C CG . ASN A 1 106 ? -66.352 -20.475 -5.220 1.00 81.48 ? 106 ASN A CG 1 ATOM 828 O OD1 . ASN A 1 106 ? -65.417 -19.890 -5.766 1.00 83.34 ? 106 ASN A OD1 1 ATOM 829 N ND2 . ASN A 1 106 ? -67.598 -19.979 -5.176 1.00 87.64 ? 106 ASN A ND2 1 ATOM 830 N N . ALA A 1 107 ? -62.707 -22.993 -3.826 1.00 74.59 ? 107 ALA A N 1 ATOM 831 C CA . ALA A 1 107 ? -61.771 -23.067 -2.691 1.00 72.91 ? 107 ALA A CA 1 ATOM 832 C C . ALA A 1 107 ? -61.203 -21.742 -2.215 1.00 71.58 ? 107 ALA A C 1 ATOM 833 O O . ALA A 1 107 ? -60.853 -20.896 -3.025 1.00 71.43 ? 107 ALA A O 1 ATOM 834 C CB . ALA A 1 107 ? -60.623 -24.011 -3.029 1.00 73.14 ? 107 ALA A CB 1 ATOM 835 N N . THR A 1 108 ? -61.108 -21.583 -0.895 1.00 69.95 ? 108 THR A N 1 ATOM 836 C CA . THR A 1 108 ? -60.390 -20.472 -0.281 1.00 68.36 ? 108 THR A CA 1 ATOM 837 C C . THR A 1 108 ? -58.925 -20.612 -0.668 1.00 67.52 ? 108 THR A C 1 ATOM 838 O O . THR A 1 108 ? -58.373 -21.709 -0.651 1.00 67.50 ? 108 THR A O 1 ATOM 839 C CB . THR A 1 108 ? -60.512 -20.490 1.273 1.00 68.41 ? 108 THR A CB 1 ATOM 840 O OG1 . THR A 1 108 ? -61.756 -19.929 1.674 1.00 67.58 ? 108 THR A OG1 1 ATOM 841 C CG2 . THR A 1 108 ? -59.426 -19.670 1.929 1.00 68.57 ? 108 THR A CG2 1 ATOM 842 N N . VAL A 1 109 ? -58.293 -19.500 -1.020 1.00 66.26 ? 109 VAL A N 1 ATOM 843 C CA . VAL A 1 109 ? -56.893 -19.515 -1.419 1.00 64.87 ? 109 VAL A CA 1 ATOM 844 C C . VAL A 1 109 ? -55.948 -18.969 -0.356 1.00 64.19 ? 109 VAL A C 1 ATOM 845 O O . VAL A 1 109 ? -56.195 -17.898 0.195 1.00 64.16 ? 109 VAL A O 1 ATOM 846 C CB . VAL A 1 109 ? -56.684 -18.634 -2.612 1.00 64.66 ? 109 VAL A CB 1 ATOM 847 C CG1 . VAL A 1 109 ? -55.308 -18.847 -3.135 1.00 64.49 ? 109 VAL A CG1 1 ATOM 848 C CG2 . VAL A 1 109 ? -57.701 -18.942 -3.640 1.00 64.24 ? 109 VAL A CG2 1 ATOM 849 N N . LEU A 1 110 ? -54.849 -19.678 -0.099 1.00 63.07 ? 110 LEU A N 1 ATOM 850 C CA . LEU A 1 110 ? -53.793 -19.177 0.791 1.00 62.18 ? 110 LEU A CA 1 ATOM 851 C C . LEU A 1 110 ? -52.560 -18.740 0.017 1.00 61.33 ? 110 LEU A C 1 ATOM 852 O O . LEU A 1 110 ? -52.008 -19.527 -0.724 1.00 61.54 ? 110 LEU A O 1 ATOM 853 C CB . LEU A 1 110 ? -53.362 -20.255 1.789 1.00 62.16 ? 110 LEU A CB 1 ATOM 854 C CG . LEU A 1 110 ? -54.130 -20.344 3.095 1.00 61.73 ? 110 LEU A CG 1 ATOM 855 C CD1 . LEU A 1 110 ? -55.589 -20.162 2.786 1.00 62.71 ? 110 LEU A CD1 1 ATOM 856 C CD2 . LEU A 1 110 ? -53.896 -21.672 3.766 1.00 59.84 ? 110 LEU A CD2 1 ATOM 857 N N . ILE A 1 111 ? -52.104 -17.510 0.207 1.00 60.27 ? 111 ILE A N 1 ATOM 858 C CA . ILE A 1 111 ? -50.878 -17.076 -0.443 1.00 59.53 ? 111 ILE A CA 1 ATOM 859 C C . ILE A 1 111 ? -49.711 -16.955 0.520 1.00 59.73 ? 111 ILE A C 1 ATOM 860 O O . ILE A 1 111 ? -49.771 -16.193 1.485 1.00 60.30 ? 111 ILE A O 1 ATOM 861 C CB . ILE A 1 111 ? -51.067 -15.753 -1.143 1.00 59.18 ? 111 ILE A CB 1 ATOM 862 C CG1 . ILE A 1 111 ? -52.260 -15.852 -2.100 1.00 58.70 ? 111 ILE A CG1 1 ATOM 863 C CG2 . ILE A 1 111 ? -49.788 -15.366 -1.855 1.00 58.33 ? 111 ILE A CG2 1 ATOM 864 C CD1 . ILE A 1 111 ? -52.565 -14.590 -2.831 1.00 57.69 ? 111 ILE A CD1 1 ATOM 865 N N . TRP A 1 112 ? -48.644 -17.705 0.272 1.00 59.32 ? 112 TRP A N 1 ATOM 866 C CA . TRP A 1 112 ? -47.486 -17.636 1.140 1.00 59.21 ? 112 TRP A CA 1 ATOM 867 C C . TRP A 1 112 ? -46.477 -16.560 0.741 1.00 59.12 ? 112 TRP A C 1 ATOM 868 O O . TRP A 1 112 ? -46.170 -16.396 -0.422 1.00 59.37 ? 112 TRP A O 1 ATOM 869 C CB . TRP A 1 112 ? -46.783 -18.969 1.152 1.00 59.24 ? 112 TRP A CB 1 ATOM 870 C CG . TRP A 1 112 ? -45.583 -18.949 2.010 1.00 60.27 ? 112 TRP A CG 1 ATOM 871 C CD1 . TRP A 1 112 ? -44.292 -18.962 1.600 1.00 60.37 ? 112 TRP A CD1 1 ATOM 872 C CD2 . TRP A 1 112 ? -45.553 -18.866 3.445 1.00 61.34 ? 112 TRP A CD2 1 ATOM 873 N NE1 . TRP A 1 112 ? -43.455 -18.906 2.684 1.00 61.94 ? 112 TRP A NE1 1 ATOM 874 C CE2 . TRP A 1 112 ? -44.209 -18.852 3.829 1.00 62.17 ? 112 TRP A CE2 1 ATOM 875 C CE3 . TRP A 1 112 ? -46.535 -18.803 4.436 1.00 61.41 ? 112 TRP A CE3 1 ATOM 876 C CZ2 . TRP A 1 112 ? -43.819 -18.791 5.169 1.00 62.99 ? 112 TRP A CZ2 1 ATOM 877 C CZ3 . TRP A 1 112 ? -46.147 -18.745 5.763 1.00 61.74 ? 112 TRP A CZ3 1 ATOM 878 C CH2 . TRP A 1 112 ? -44.806 -18.745 6.118 1.00 62.21 ? 112 TRP A CH2 1 ATOM 879 N N . ILE A 1 113 ? -45.947 -15.827 1.707 1.00 58.90 ? 113 ILE A N 1 ATOM 880 C CA . ILE A 1 113 ? -44.856 -14.906 1.416 1.00 58.60 ? 113 ILE A CA 1 ATOM 881 C C . ILE A 1 113 ? -43.620 -15.242 2.254 1.00 59.20 ? 113 ILE A C 1 ATOM 882 O O . ILE A 1 113 ? -43.689 -15.209 3.481 1.00 59.51 ? 113 ILE A O 1 ATOM 883 C CB . ILE A 1 113 ? -45.277 -13.494 1.713 1.00 58.14 ? 113 ILE A CB 1 ATOM 884 C CG1 . ILE A 1 113 ? -46.521 -13.163 0.898 1.00 57.25 ? 113 ILE A CG1 1 ATOM 885 C CG2 . ILE A 1 113 ? -44.146 -12.556 1.396 1.00 58.04 ? 113 ILE A CG2 1 ATOM 886 C CD1 . ILE A 1 113 ? -47.037 -11.771 1.087 1.00 54.88 ? 113 ILE A CD1 1 ATOM 887 N N . TYR A 1 114 ? -42.502 -15.576 1.607 1.00 59.25 ? 114 TYR A N 1 ATOM 888 C CA . TYR A 1 114 ? -41.330 -16.050 2.345 1.00 59.32 ? 114 TYR A CA 1 ATOM 889 C C . TYR A 1 114 ? -40.584 -14.937 3.106 1.00 59.52 ? 114 TYR A C 1 ATOM 890 O O . TYR A 1 114 ? -40.550 -13.796 2.654 1.00 59.21 ? 114 TYR A O 1 ATOM 891 C CB . TYR A 1 114 ? -40.373 -16.855 1.445 1.00 59.37 ? 114 TYR A CB 1 ATOM 892 C CG . TYR A 1 114 ? -39.863 -16.144 0.193 1.00 59.17 ? 114 TYR A CG 1 ATOM 893 C CD1 . TYR A 1 114 ? -38.842 -15.199 0.259 1.00 59.15 ? 114 TYR A CD1 1 ATOM 894 C CD2 . TYR A 1 114 ? -40.383 -16.443 -1.054 1.00 58.95 ? 114 TYR A CD2 1 ATOM 895 C CE1 . TYR A 1 114 ? -38.362 -14.556 -0.896 1.00 58.80 ? 114 TYR A CE1 1 ATOM 896 C CE2 . TYR A 1 114 ? -39.924 -15.805 -2.208 1.00 59.16 ? 114 TYR A CE2 1 ATOM 897 C CZ . TYR A 1 114 ? -38.915 -14.864 -2.126 1.00 59.10 ? 114 TYR A CZ 1 ATOM 898 O OH . TYR A 1 114 ? -38.494 -14.247 -3.287 1.00 57.46 ? 114 TYR A OH 1 ATOM 899 N N . GLY A 1 115 ? -40.021 -15.290 4.269 1.00 59.66 ? 115 GLY A N 1 ATOM 900 C CA . GLY A 1 115 ? -39.174 -14.415 5.072 1.00 59.78 ? 115 GLY A CA 1 ATOM 901 C C . GLY A 1 115 ? -37.720 -14.426 4.628 1.00 60.19 ? 115 GLY A C 1 ATOM 902 O O . GLY A 1 115 ? -37.400 -14.899 3.547 1.00 60.22 ? 115 GLY A O 1 ATOM 903 N N . GLY A 1 116 ? -36.830 -13.885 5.446 1.00 60.40 ? 116 GLY A N 1 ATOM 904 C CA . GLY A 1 116 ? -35.439 -13.748 5.051 1.00 60.78 ? 116 GLY A CA 1 ATOM 905 C C . GLY A 1 116 ? -35.036 -12.305 4.854 1.00 61.26 ? 116 GLY A C 1 ATOM 906 O O . GLY A 1 116 ? -34.511 -11.926 3.799 1.00 61.32 ? 116 GLY A O 1 ATOM 907 N N . GLY A 1 117 ? -35.306 -11.498 5.875 1.00 61.64 ? 117 GLY A N 1 ATOM 908 C CA . GLY A 1 117 ? -34.922 -10.082 5.912 1.00 61.99 ? 117 GLY A CA 1 ATOM 909 C C . GLY A 1 117 ? -34.990 -9.250 4.638 1.00 62.38 ? 117 GLY A C 1 ATOM 910 O O . GLY A 1 117 ? -34.234 -8.302 4.480 1.00 62.55 ? 117 GLY A O 1 ATOM 911 N N . PHE A 1 118 ? -35.897 -9.568 3.732 1.00 62.79 ? 118 PHE A N 1 ATOM 912 C CA . PHE A 1 118 ? -35.908 -8.889 2.450 1.00 63.50 ? 118 PHE A CA 1 ATOM 913 C C . PHE A 1 118 ? -34.574 -9.050 1.718 1.00 63.95 ? 118 PHE A C 1 ATOM 914 O O . PHE A 1 118 ? -34.323 -8.408 0.701 1.00 63.98 ? 118 PHE A O 1 ATOM 915 C CB . PHE A 1 118 ? -36.278 -7.417 2.642 1.00 63.38 ? 118 PHE A CB 1 ATOM 916 C CG . PHE A 1 118 ? -37.656 -7.215 3.220 1.00 63.80 ? 118 PHE A CG 1 ATOM 917 C CD1 . PHE A 1 118 ? -38.796 -7.397 2.449 1.00 63.74 ? 118 PHE A CD1 1 ATOM 918 C CD2 . PHE A 1 118 ? -37.819 -6.881 4.544 1.00 63.76 ? 118 PHE A CD2 1 ATOM 919 C CE1 . PHE A 1 118 ? -40.065 -7.237 3.004 1.00 63.07 ? 118 PHE A CE1 1 ATOM 920 C CE2 . PHE A 1 118 ? -39.080 -6.710 5.094 1.00 62.66 ? 118 PHE A CE2 1 ATOM 921 C CZ . PHE A 1 118 ? -40.197 -6.888 4.328 1.00 62.36 ? 118 PHE A CZ 1 ATOM 922 N N . GLN A 1 119 ? -33.723 -9.928 2.230 1.00 64.63 ? 119 GLN A N 1 ATOM 923 C CA . GLN A 1 119 ? -32.422 -10.140 1.626 1.00 65.50 ? 119 GLN A CA 1 ATOM 924 C C . GLN A 1 119 ? -32.331 -11.531 0.997 1.00 66.15 ? 119 GLN A C 1 ATOM 925 O O . GLN A 1 119 ? -31.693 -11.717 -0.052 1.00 66.66 ? 119 GLN A O 1 ATOM 926 C CB . GLN A 1 119 ? -31.313 -9.961 2.663 1.00 65.40 ? 119 GLN A CB 1 ATOM 927 C CG . GLN A 1 119 ? -31.360 -8.659 3.425 1.00 66.23 ? 119 GLN A CG 1 ATOM 928 C CD . GLN A 1 119 ? -31.510 -7.441 2.519 1.00 68.61 ? 119 GLN A CD 1 ATOM 929 O OE1 . GLN A 1 119 ? -32.334 -6.554 2.774 1.00 69.23 ? 119 GLN A OE1 1 ATOM 930 N NE2 . GLN A 1 119 ? -30.719 -7.395 1.450 1.00 69.85 ? 119 GLN A NE2 1 ATOM 931 N N . THR A 1 120 ? -32.970 -12.507 1.637 1.00 66.09 ? 120 THR A N 1 ATOM 932 C CA . THR A 1 120 ? -32.860 -13.880 1.191 1.00 65.72 ? 120 THR A CA 1 ATOM 933 C C . THR A 1 120 ? -34.218 -14.548 1.159 1.00 65.86 ? 120 THR A C 1 ATOM 934 O O . THR A 1 120 ? -35.188 -13.991 1.648 1.00 65.97 ? 120 THR A O 1 ATOM 935 C CB . THR A 1 120 ? -31.993 -14.655 2.131 1.00 65.38 ? 120 THR A CB 1 ATOM 936 O OG1 . THR A 1 120 ? -32.700 -14.809 3.354 1.00 65.17 ? 120 THR A OG1 1 ATOM 937 C CG2 . THR A 1 120 ? -30.717 -13.906 2.384 1.00 64.60 ? 120 THR A CG2 1 ATOM 938 N N . GLY A 1 121 ? -34.276 -15.742 0.575 1.00 65.94 ? 121 GLY A N 1 ATOM 939 C CA . GLY A 1 121 ? -35.504 -16.518 0.527 1.00 65.78 ? 121 GLY A CA 1 ATOM 940 C C . GLY A 1 121 ? -35.984 -16.917 -0.853 1.00 65.50 ? 121 GLY A C 1 ATOM 941 O O . GLY A 1 121 ? -35.620 -16.312 -1.846 1.00 64.99 ? 121 GLY A O 1 ATOM 942 N N . THR A 1 122 ? -36.813 -17.956 -0.893 1.00 65.59 ? 122 THR A N 1 ATOM 943 C CA . THR A 1 122 ? -37.406 -18.460 -2.133 1.00 65.42 ? 122 THR A CA 1 ATOM 944 C C . THR A 1 122 ? -38.594 -19.364 -1.812 1.00 65.41 ? 122 THR A C 1 ATOM 945 O O . THR A 1 122 ? -38.641 -19.995 -0.763 1.00 65.58 ? 122 THR A O 1 ATOM 946 C CB . THR A 1 122 ? -36.397 -19.221 -3.015 1.00 64.99 ? 122 THR A CB 1 ATOM 947 O OG1 . THR A 1 122 ? -36.985 -19.442 -4.293 1.00 65.55 ? 122 THR A OG1 1 ATOM 948 C CG2 . THR A 1 122 ? -36.048 -20.564 -2.428 1.00 64.39 ? 122 THR A CG2 1 ATOM 949 N N . SER A 1 123 ? -39.559 -19.414 -2.715 1.00 65.34 ? 123 SER A N 1 ATOM 950 C CA . SER A 1 123 ? -40.801 -20.124 -2.455 1.00 65.29 ? 123 SER A CA 1 ATOM 951 C C . SER A 1 123 ? -40.615 -21.640 -2.523 1.00 65.71 ? 123 SER A C 1 ATOM 952 O O . SER A 1 123 ? -41.427 -22.397 -1.982 1.00 65.82 ? 123 SER A O 1 ATOM 953 C CB . SER A 1 123 ? -41.854 -19.693 -3.471 1.00 65.18 ? 123 SER A CB 1 ATOM 954 O OG . SER A 1 123 ? -41.416 -19.974 -4.780 1.00 63.63 ? 123 SER A OG 1 ATOM 955 N N . SER A 1 124 ? -39.536 -22.077 -3.175 1.00 65.88 ? 124 SER A N 1 ATOM 956 C CA . SER A 1 124 ? -39.323 -23.495 -3.472 1.00 65.71 ? 124 SER A CA 1 ATOM 957 C C . SER A 1 124 ? -38.845 -24.332 -2.287 1.00 65.78 ? 124 SER A C 1 ATOM 958 O O . SER A 1 124 ? -38.708 -25.541 -2.400 1.00 65.68 ? 124 SER A O 1 ATOM 959 C CB . SER A 1 124 ? -38.360 -23.655 -4.657 1.00 65.67 ? 124 SER A CB 1 ATOM 960 O OG . SER A 1 124 ? -37.465 -22.563 -4.772 1.00 65.57 ? 124 SER A OG 1 ATOM 961 N N . LEU A 1 125 ? -38.590 -23.695 -1.153 1.00 66.19 ? 125 LEU A N 1 ATOM 962 C CA . LEU A 1 125 ? -38.138 -24.410 0.042 1.00 66.65 ? 125 LEU A CA 1 ATOM 963 C C . LEU A 1 125 ? -39.086 -25.549 0.414 1.00 67.34 ? 125 LEU A C 1 ATOM 964 O O . LEU A 1 125 ? -40.305 -25.437 0.270 1.00 67.38 ? 125 LEU A O 1 ATOM 965 C CB . LEU A 1 125 ? -37.998 -23.473 1.242 1.00 66.33 ? 125 LEU A CB 1 ATOM 966 C CG . LEU A 1 125 ? -36.903 -22.428 1.314 1.00 65.45 ? 125 LEU A CG 1 ATOM 967 C CD1 . LEU A 1 125 ? -36.285 -22.584 2.643 1.00 65.15 ? 125 LEU A CD1 1 ATOM 968 C CD2 . LEU A 1 125 ? -35.850 -22.656 0.271 1.00 65.97 ? 125 LEU A CD2 1 ATOM 969 N N . HIS A 1 126 ? -38.514 -26.641 0.901 1.00 67.81 ? 126 HIS A N 1 ATOM 970 C CA . HIS A 1 126 ? -39.281 -27.800 1.266 1.00 68.33 ? 126 HIS A CA 1 ATOM 971 C C . HIS A 1 126 ? -40.321 -27.435 2.326 1.00 68.11 ? 126 HIS A C 1 ATOM 972 O O . HIS A 1 126 ? -41.457 -27.895 2.275 1.00 68.16 ? 126 HIS A O 1 ATOM 973 C CB . HIS A 1 126 ? -38.322 -28.894 1.743 1.00 68.90 ? 126 HIS A CB 1 ATOM 974 C CG . HIS A 1 126 ? -38.998 -30.115 2.287 1.00 71.78 ? 126 HIS A CG 1 ATOM 975 N ND1 . HIS A 1 126 ? -39.961 -30.816 1.588 1.00 74.25 ? 126 HIS A ND1 1 ATOM 976 C CD2 . HIS A 1 126 ? -38.839 -30.770 3.463 1.00 74.12 ? 126 HIS A CD2 1 ATOM 977 C CE1 . HIS A 1 126 ? -40.377 -31.837 2.317 1.00 75.18 ? 126 HIS A CE1 1 ATOM 978 N NE2 . HIS A 1 126 ? -39.712 -31.833 3.459 1.00 75.46 ? 126 HIS A NE2 1 ATOM 979 N N . VAL A 1 127 ? -39.942 -26.581 3.269 1.00 68.11 ? 127 VAL A N 1 ATOM 980 C CA . VAL A 1 127 ? -40.836 -26.159 4.360 1.00 67.79 ? 127 VAL A CA 1 ATOM 981 C C . VAL A 1 127 ? -42.006 -25.285 3.922 1.00 67.74 ? 127 VAL A C 1 ATOM 982 O O . VAL A 1 127 ? -42.897 -25.007 4.717 1.00 67.58 ? 127 VAL A O 1 ATOM 983 C CB . VAL A 1 127 ? -40.081 -25.372 5.436 1.00 67.57 ? 127 VAL A CB 1 ATOM 984 C CG1 . VAL A 1 127 ? -39.556 -26.296 6.468 1.00 67.57 ? 127 VAL A CG1 1 ATOM 985 C CG2 . VAL A 1 127 ? -38.957 -24.595 4.812 1.00 67.60 ? 127 VAL A CG2 1 ATOM 986 N N . TYR A 1 128 ? -41.986 -24.827 2.676 1.00 67.70 ? 128 TYR A N 1 ATOM 987 C CA . TYR A 1 128 ? -43.081 -24.050 2.127 1.00 67.53 ? 128 TYR A CA 1 ATOM 988 C C . TYR A 1 128 ? -43.877 -24.870 1.118 1.00 67.85 ? 128 TYR A C 1 ATOM 989 O O . TYR A 1 128 ? -44.307 -24.341 0.101 1.00 67.75 ? 128 TYR A O 1 ATOM 990 C CB . TYR A 1 128 ? -42.533 -22.829 1.403 1.00 67.25 ? 128 TYR A CB 1 ATOM 991 C CG . TYR A 1 128 ? -41.607 -21.939 2.199 1.00 66.43 ? 128 TYR A CG 1 ATOM 992 C CD1 . TYR A 1 128 ? -41.708 -21.831 3.574 1.00 65.29 ? 128 TYR A CD1 1 ATOM 993 C CD2 . TYR A 1 128 ? -40.666 -21.157 1.555 1.00 65.89 ? 128 TYR A CD2 1 ATOM 994 C CE1 . TYR A 1 128 ? -40.879 -20.994 4.286 1.00 64.79 ? 128 TYR A CE1 1 ATOM 995 C CE2 . TYR A 1 128 ? -39.828 -20.323 2.254 1.00 65.54 ? 128 TYR A CE2 1 ATOM 996 C CZ . TYR A 1 128 ? -39.942 -20.239 3.619 1.00 64.99 ? 128 TYR A CZ 1 ATOM 997 O OH . TYR A 1 128 ? -39.112 -19.396 4.308 1.00 62.83 ? 128 TYR A OH 1 ATOM 998 N N . ASP A 1 129 ? -44.056 -26.161 1.370 1.00 68.20 ? 129 ASP A N 1 ATOM 999 C CA . ASP A 1 129 ? -44.655 -27.026 0.361 1.00 68.70 ? 129 ASP A CA 1 ATOM 1000 C C . ASP A 1 129 ? -46.162 -27.068 0.509 1.00 68.66 ? 129 ASP A C 1 ATOM 1001 O O . ASP A 1 129 ? -46.683 -27.705 1.410 1.00 68.35 ? 129 ASP A O 1 ATOM 1002 C CB . ASP A 1 129 ? -44.066 -28.439 0.417 1.00 69.06 ? 129 ASP A CB 1 ATOM 1003 C CG . ASP A 1 129 ? -44.272 -29.226 -0.888 1.00 69.96 ? 129 ASP A CG 1 ATOM 1004 O OD1 . ASP A 1 129 ? -45.190 -28.915 -1.692 1.00 70.31 ? 129 ASP A OD1 1 ATOM 1005 O OD2 . ASP A 1 129 ? -43.497 -30.178 -1.102 1.00 70.75 ? 129 ASP A OD2 1 ATOM 1006 N N . GLY A 1 130 ? -46.854 -26.401 -0.407 1.00 68.80 ? 130 GLY A N 1 ATOM 1007 C CA . GLY A 1 130 ? -48.303 -26.270 -0.345 1.00 69.03 ? 130 GLY A CA 1 ATOM 1008 C C . GLY A 1 130 ? -49.071 -27.552 -0.577 1.00 69.20 ? 130 GLY A C 1 ATOM 1009 O O . GLY A 1 130 ? -50.272 -27.630 -0.297 1.00 69.20 ? 130 GLY A O 1 ATOM 1010 N N . LYS A 1 131 ? -48.376 -28.571 -1.065 1.00 69.28 ? 131 LYS A N 1 ATOM 1011 C CA . LYS A 1 131 ? -49.033 -29.808 -1.440 1.00 69.27 ? 131 LYS A CA 1 ATOM 1012 C C . LYS A 1 131 ? -49.844 -30.431 -0.300 1.00 69.24 ? 131 LYS A C 1 ATOM 1013 O O . LYS A 1 131 ? -50.949 -30.907 -0.526 1.00 69.37 ? 131 LYS A O 1 ATOM 1014 C CB . LYS A 1 131 ? -48.034 -30.791 -2.034 1.00 69.28 ? 131 LYS A CB 1 ATOM 1015 C CG . LYS A 1 131 ? -47.361 -31.634 -1.028 1.00 69.62 ? 131 LYS A CG 1 ATOM 1016 C CD . LYS A 1 131 ? -46.236 -32.383 -1.671 1.00 70.56 ? 131 LYS A CD 1 ATOM 1017 C CE . LYS A 1 131 ? -45.907 -33.595 -0.841 1.00 71.84 ? 131 LYS A CE 1 ATOM 1018 N NZ . LYS A 1 131 ? -44.517 -34.042 -1.124 1.00 72.93 ? 131 LYS A NZ 1 ATOM 1019 N N . PHE A 1 132 ? -49.329 -30.406 0.924 1.00 69.22 ? 132 PHE A N 1 ATOM 1020 C CA . PHE A 1 132 ? -50.075 -30.950 2.072 1.00 69.42 ? 132 PHE A CA 1 ATOM 1021 C C . PHE A 1 132 ? -51.342 -30.164 2.422 1.00 68.85 ? 132 PHE A C 1 ATOM 1022 O O . PHE A 1 132 ? -52.365 -30.742 2.789 1.00 68.58 ? 132 PHE A O 1 ATOM 1023 C CB . PHE A 1 132 ? -49.188 -31.042 3.322 1.00 69.98 ? 132 PHE A CB 1 ATOM 1024 C CG . PHE A 1 132 ? -47.872 -31.706 3.078 1.00 72.67 ? 132 PHE A CG 1 ATOM 1025 C CD1 . PHE A 1 132 ? -47.785 -33.080 3.008 1.00 74.27 ? 132 PHE A CD1 1 ATOM 1026 C CD2 . PHE A 1 132 ? -46.724 -30.955 2.894 1.00 75.22 ? 132 PHE A CD2 1 ATOM 1027 C CE1 . PHE A 1 132 ? -46.591 -33.693 2.762 1.00 75.27 ? 132 PHE A CE1 1 ATOM 1028 C CE2 . PHE A 1 132 ? -45.523 -31.563 2.644 1.00 75.85 ? 132 PHE A CE2 1 ATOM 1029 C CZ . PHE A 1 132 ? -45.453 -32.935 2.588 1.00 76.48 ? 132 PHE A CZ 1 ATOM 1030 N N . LEU A 1 133 ? -51.269 -28.841 2.346 1.00 68.29 ? 133 LEU A N 1 ATOM 1031 C CA . LEU A 1 133 ? -52.384 -28.029 2.785 1.00 67.89 ? 133 LEU A CA 1 ATOM 1032 C C . LEU A 1 133 ? -53.516 -28.222 1.818 1.00 67.86 ? 133 LEU A C 1 ATOM 1033 O O . LEU A 1 133 ? -54.678 -28.271 2.212 1.00 67.78 ? 133 LEU A O 1 ATOM 1034 C CB . LEU A 1 133 ? -51.999 -26.549 2.902 1.00 67.85 ? 133 LEU A CB 1 ATOM 1035 C CG . LEU A 1 133 ? -51.342 -26.144 4.231 1.00 67.33 ? 133 LEU A CG 1 ATOM 1036 C CD1 . LEU A 1 133 ? -50.705 -24.778 4.136 1.00 66.96 ? 133 LEU A CD1 1 ATOM 1037 C CD2 . LEU A 1 133 ? -52.316 -26.202 5.398 1.00 65.22 ? 133 LEU A CD2 1 ATOM 1038 N N . ALA A 1 134 ? -53.170 -28.341 0.543 1.00 67.79 ? 134 ALA A N 1 ATOM 1039 C CA . ALA A 1 134 ? -54.178 -28.566 -0.464 1.00 67.63 ? 134 ALA A CA 1 ATOM 1040 C C . ALA A 1 134 ? -54.832 -29.886 -0.124 1.00 67.68 ? 134 ALA A C 1 ATOM 1041 O O . ALA A 1 134 ? -56.048 -29.976 -0.001 1.00 67.92 ? 134 ALA A O 1 ATOM 1042 C CB . ALA A 1 134 ? -53.569 -28.615 -1.819 1.00 67.58 ? 134 ALA A CB 1 ATOM 1043 N N . ARG A 1 135 ? -54.019 -30.912 0.067 1.00 67.45 ? 135 ARG A N 1 ATOM 1044 C CA . ARG A 1 135 ? -54.563 -32.223 0.328 1.00 67.46 ? 135 ARG A CA 1 ATOM 1045 C C . ARG A 1 135 ? -55.474 -32.221 1.524 1.00 66.60 ? 135 ARG A C 1 ATOM 1046 O O . ARG A 1 135 ? -56.592 -32.678 1.437 1.00 66.80 ? 135 ARG A O 1 ATOM 1047 C CB . ARG A 1 135 ? -53.452 -33.248 0.527 1.00 68.10 ? 135 ARG A CB 1 ATOM 1048 C CG . ARG A 1 135 ? -53.948 -34.695 0.713 1.00 70.89 ? 135 ARG A CG 1 ATOM 1049 C CD . ARG A 1 135 ? -55.091 -35.072 -0.250 1.00 75.30 ? 135 ARG A CD 1 ATOM 1050 N NE . ARG A 1 135 ? -55.415 -36.500 -0.195 1.00 79.08 ? 135 ARG A NE 1 ATOM 1051 C CZ . ARG A 1 135 ? -55.952 -37.112 0.860 1.00 80.95 ? 135 ARG A CZ 1 ATOM 1052 N NH1 . ARG A 1 135 ? -56.220 -36.426 1.965 1.00 81.87 ? 135 ARG A NH1 1 ATOM 1053 N NH2 . ARG A 1 135 ? -56.213 -38.414 0.817 1.00 81.92 ? 135 ARG A NH2 1 ATOM 1054 N N . VAL A 1 136 ? -55.006 -31.694 2.642 1.00 65.91 ? 136 VAL A N 1 ATOM 1055 C CA . VAL A 1 136 ? -55.721 -31.898 3.884 1.00 65.03 ? 136 VAL A CA 1 ATOM 1056 C C . VAL A 1 136 ? -56.917 -31.001 4.137 1.00 65.00 ? 136 VAL A C 1 ATOM 1057 O O . VAL A 1 136 ? -57.908 -31.474 4.672 1.00 65.21 ? 136 VAL A O 1 ATOM 1058 C CB . VAL A 1 136 ? -54.812 -31.808 5.085 1.00 64.80 ? 136 VAL A CB 1 ATOM 1059 C CG1 . VAL A 1 136 ? -55.614 -32.091 6.338 1.00 64.11 ? 136 VAL A CG1 1 ATOM 1060 C CG2 . VAL A 1 136 ? -53.690 -32.780 4.929 1.00 64.25 ? 136 VAL A CG2 1 ATOM 1061 N N . GLU A 1 137 ? -56.829 -29.723 3.779 1.00 64.57 ? 137 GLU A N 1 ATOM 1062 C CA . GLU A 1 137 ? -57.877 -28.779 4.121 1.00 64.29 ? 137 GLU A CA 1 ATOM 1063 C C . GLU A 1 137 ? -58.577 -28.333 2.885 1.00 64.70 ? 137 GLU A C 1 ATOM 1064 O O . GLU A 1 137 ? -59.439 -27.474 2.919 1.00 64.61 ? 137 GLU A O 1 ATOM 1065 C CB . GLU A 1 137 ? -57.312 -27.572 4.853 1.00 64.12 ? 137 GLU A CB 1 ATOM 1066 C CG . GLU A 1 137 ? -56.879 -27.880 6.276 1.00 62.39 ? 137 GLU A CG 1 ATOM 1067 C CD . GLU A 1 137 ? -58.015 -28.356 7.141 1.00 61.15 ? 137 GLU A CD 1 ATOM 1068 O OE1 . GLU A 1 137 ? -59.120 -27.805 7.043 1.00 59.94 ? 137 GLU A OE1 1 ATOM 1069 O OE2 . GLU A 1 137 ? -57.800 -29.289 7.929 1.00 61.21 ? 137 GLU A OE2 1 ATOM 1070 N N . ARG A 1 138 ? -58.188 -28.936 1.782 1.00 65.40 ? 138 ARG A N 1 ATOM 1071 C CA . ARG A 1 138 ? -58.807 -28.662 0.507 1.00 66.20 ? 138 ARG A CA 1 ATOM 1072 C C . ARG A 1 138 ? -58.893 -27.171 0.234 1.00 65.25 ? 138 ARG A C 1 ATOM 1073 O O . ARG A 1 138 ? -59.952 -26.634 -0.028 1.00 65.32 ? 138 ARG A O 1 ATOM 1074 C CB . ARG A 1 138 ? -60.166 -29.380 0.400 1.00 67.01 ? 138 ARG A CB 1 ATOM 1075 C CG . ARG A 1 138 ? -60.069 -30.932 0.534 1.00 71.04 ? 138 ARG A CG 1 ATOM 1076 C CD . ARG A 1 138 ? -61.314 -31.647 -0.014 1.00 78.97 ? 138 ARG A CD 1 ATOM 1077 N NE . ARG A 1 138 ? -61.544 -31.363 -1.445 1.00 85.22 ? 138 ARG A NE 1 ATOM 1078 C CZ . ARG A 1 138 ? -61.000 -32.059 -2.456 1.00 87.99 ? 138 ARG A CZ 1 ATOM 1079 N NH1 . ARG A 1 138 ? -61.260 -31.726 -3.724 1.00 87.52 ? 138 ARG A NH1 1 ATOM 1080 N NH2 . ARG A 1 138 ? -60.186 -33.090 -2.203 1.00 88.84 ? 138 ARG A NH2 1 ATOM 1081 N N . VAL A 1 139 ? -57.748 -26.513 0.297 1.00 64.68 ? 139 VAL A N 1 ATOM 1082 C CA . VAL A 1 139 ? -57.612 -25.152 -0.201 1.00 64.36 ? 139 VAL A CA 1 ATOM 1083 C C . VAL A 1 139 ? -56.568 -25.043 -1.298 1.00 64.26 ? 139 VAL A C 1 ATOM 1084 O O . VAL A 1 139 ? -55.754 -25.941 -1.502 1.00 64.50 ? 139 VAL A O 1 ATOM 1085 C CB . VAL A 1 139 ? -57.132 -24.204 0.866 1.00 64.11 ? 139 VAL A CB 1 ATOM 1086 C CG1 . VAL A 1 139 ? -58.241 -23.907 1.824 1.00 64.22 ? 139 VAL A CG1 1 ATOM 1087 C CG2 . VAL A 1 139 ? -55.929 -24.799 1.563 1.00 64.07 ? 139 VAL A CG2 1 ATOM 1088 N N . ILE A 1 140 ? -56.576 -23.918 -1.992 1.00 63.70 ? 140 ILE A N 1 ATOM 1089 C CA . ILE A 1 140 ? -55.552 -23.660 -2.974 1.00 63.05 ? 140 ILE A CA 1 ATOM 1090 C C . ILE A 1 140 ? -54.469 -22.851 -2.306 1.00 62.65 ? 140 ILE A C 1 ATOM 1091 O O . ILE A 1 140 ? -54.750 -21.882 -1.615 1.00 63.03 ? 140 ILE A O 1 ATOM 1092 C CB . ILE A 1 140 ? -56.102 -22.874 -4.154 1.00 63.06 ? 140 ILE A CB 1 ATOM 1093 C CG1 . ILE A 1 140 ? -57.003 -23.773 -5.003 1.00 62.73 ? 140 ILE A CG1 1 ATOM 1094 C CG2 . ILE A 1 140 ? -54.964 -22.348 -4.978 1.00 63.00 ? 140 ILE A CG2 1 ATOM 1095 C CD1 . ILE A 1 140 ? -58.068 -23.039 -5.758 1.00 62.90 ? 140 ILE A CD1 1 ATOM 1096 N N . VAL A 1 141 ? -53.225 -23.259 -2.497 1.00 61.87 ? 141 VAL A N 1 ATOM 1097 C CA . VAL A 1 141 ? -52.109 -22.553 -1.904 1.00 61.07 ? 141 VAL A CA 1 ATOM 1098 C C . VAL A 1 141 ? -51.276 -21.935 -3.010 1.00 60.73 ? 141 VAL A C 1 ATOM 1099 O O . VAL A 1 141 ? -50.910 -22.603 -3.945 1.00 61.02 ? 141 VAL A O 1 ATOM 1100 C CB . VAL A 1 141 ? -51.203 -23.489 -1.092 1.00 60.88 ? 141 VAL A CB 1 ATOM 1101 C CG1 . VAL A 1 141 ? -50.095 -22.687 -0.469 1.00 60.71 ? 141 VAL A CG1 1 ATOM 1102 C CG2 . VAL A 1 141 ? -51.989 -24.233 -0.038 1.00 60.12 ? 141 VAL A CG2 1 ATOM 1103 N N . VAL A 1 142 ? -50.964 -20.661 -2.907 1.00 60.16 ? 142 VAL A N 1 ATOM 1104 C CA . VAL A 1 142 ? -50.148 -20.033 -3.915 1.00 59.74 ? 142 VAL A CA 1 ATOM 1105 C C . VAL A 1 142 ? -48.965 -19.428 -3.231 1.00 59.88 ? 142 VAL A C 1 ATOM 1106 O O . VAL A 1 142 ? -49.099 -18.890 -2.152 1.00 60.07 ? 142 VAL A O 1 ATOM 1107 C CB . VAL A 1 142 ? -50.883 -18.890 -4.573 1.00 59.67 ? 142 VAL A CB 1 ATOM 1108 C CG1 . VAL A 1 142 ? -49.927 -18.098 -5.414 1.00 58.82 ? 142 VAL A CG1 1 ATOM 1109 C CG2 . VAL A 1 142 ? -52.052 -19.408 -5.387 1.00 59.54 ? 142 VAL A CG2 1 ATOM 1110 N N . SER A 1 143 ? -47.792 -19.526 -3.835 1.00 59.99 ? 143 SER A N 1 ATOM 1111 C CA . SER A 1 143 ? -46.654 -18.782 -3.337 1.00 60.05 ? 143 SER A CA 1 ATOM 1112 C C . SER A 1 143 ? -45.891 -18.208 -4.498 1.00 60.42 ? 143 SER A C 1 ATOM 1113 O O . SER A 1 143 ? -45.976 -18.715 -5.613 1.00 60.60 ? 143 SER A O 1 ATOM 1114 C CB . SER A 1 143 ? -45.747 -19.639 -2.465 1.00 59.83 ? 143 SER A CB 1 ATOM 1115 O OG . SER A 1 143 ? -45.279 -20.760 -3.156 1.00 59.41 ? 143 SER A OG 1 ATOM 1116 N N . MET A 1 144 ? -45.155 -17.136 -4.245 1.00 60.75 ? 144 MET A N 1 ATOM 1117 C CA . MET A 1 144 ? -44.427 -16.476 -5.319 1.00 61.29 ? 144 MET A CA 1 ATOM 1118 C C . MET A 1 144 ? -43.031 -16.141 -4.849 1.00 61.36 ? 144 MET A C 1 ATOM 1119 O O . MET A 1 144 ? -42.762 -16.172 -3.650 1.00 61.62 ? 144 MET A O 1 ATOM 1120 C CB . MET A 1 144 ? -45.123 -15.181 -5.729 1.00 61.43 ? 144 MET A CB 1 ATOM 1121 C CG . MET A 1 144 ? -44.701 -13.972 -4.908 1.00 61.97 ? 144 MET A CG 1 ATOM 1122 S SD . MET A 1 144 ? -45.281 -14.017 -3.216 1.00 64.03 ? 144 MET A SD 1 ATOM 1123 C CE . MET A 1 144 ? -47.019 -13.737 -3.399 1.00 62.91 ? 144 MET A CE 1 ATOM 1124 N N . ASN A 1 145 ? -42.147 -15.835 -5.798 1.00 61.14 ? 145 ASN A N 1 ATOM 1125 C CA . ASN A 1 145 ? -40.833 -15.291 -5.487 1.00 60.79 ? 145 ASN A CA 1 ATOM 1126 C C . ASN A 1 145 ? -40.849 -13.818 -5.765 1.00 60.48 ? 145 ASN A C 1 ATOM 1127 O O . ASN A 1 145 ? -41.438 -13.381 -6.759 1.00 60.66 ? 145 ASN A O 1 ATOM 1128 C CB . ASN A 1 145 ? -39.794 -15.890 -6.404 1.00 60.88 ? 145 ASN A CB 1 ATOM 1129 C CG . ASN A 1 145 ? -39.548 -17.312 -6.122 1.00 61.29 ? 145 ASN A CG 1 ATOM 1130 O OD1 . ASN A 1 145 ? -40.101 -17.891 -5.169 1.00 60.16 ? 145 ASN A OD1 1 ATOM 1131 N ND2 . ASN A 1 145 ? -38.704 -17.913 -6.945 1.00 61.74 ? 145 ASN A ND2 1 ATOM 1132 N N . TYR A 1 146 ? -40.193 -13.040 -4.922 1.00 59.67 ? 146 TYR A N 1 ATOM 1133 C CA . TYR A 1 146 ? -40.121 -11.607 -5.177 1.00 59.31 ? 146 TYR A CA 1 ATOM 1134 C C . TYR A 1 146 ? -38.676 -11.164 -5.020 1.00 59.12 ? 146 TYR A C 1 ATOM 1135 O O . TYR A 1 146 ? -37.932 -11.783 -4.281 1.00 59.02 ? 146 TYR A O 1 ATOM 1136 C CB . TYR A 1 146 ? -41.036 -10.841 -4.217 1.00 59.13 ? 146 TYR A CB 1 ATOM 1137 C CG . TYR A 1 146 ? -40.697 -11.111 -2.772 1.00 58.46 ? 146 TYR A CG 1 ATOM 1138 C CD1 . TYR A 1 146 ? -39.794 -10.320 -2.089 1.00 57.01 ? 146 TYR A CD1 1 ATOM 1139 C CD2 . TYR A 1 146 ? -41.256 -12.182 -2.109 1.00 57.78 ? 146 TYR A CD2 1 ATOM 1140 C CE1 . TYR A 1 146 ? -39.477 -10.589 -0.787 1.00 56.77 ? 146 TYR A CE1 1 ATOM 1141 C CE2 . TYR A 1 146 ? -40.942 -12.456 -0.814 1.00 57.45 ? 146 TYR A CE2 1 ATOM 1142 C CZ . TYR A 1 146 ? -40.055 -11.667 -0.150 1.00 57.25 ? 146 TYR A CZ 1 ATOM 1143 O OH . TYR A 1 146 ? -39.749 -11.972 1.171 1.00 57.15 ? 146 TYR A OH 1 ATOM 1144 N N . ARG A 1 147 ? -38.271 -10.120 -5.731 1.00 58.90 ? 147 ARG A N 1 ATOM 1145 C CA . ARG A 1 147 ? -36.897 -9.662 -5.666 1.00 59.10 ? 147 ARG A CA 1 ATOM 1146 C C . ARG A 1 147 ? -36.508 -9.271 -4.241 1.00 59.20 ? 147 ARG A C 1 ATOM 1147 O O . ARG A 1 147 ? -37.291 -8.656 -3.552 1.00 59.20 ? 147 ARG A O 1 ATOM 1148 C CB . ARG A 1 147 ? -36.708 -8.483 -6.611 1.00 58.90 ? 147 ARG A CB 1 ATOM 1149 C CG . ARG A 1 147 ? -36.562 -8.893 -8.024 1.00 58.60 ? 147 ARG A CG 1 ATOM 1150 C CD . ARG A 1 147 ? -36.661 -7.699 -8.914 1.00 59.13 ? 147 ARG A CD 1 ATOM 1151 N NE . ARG A 1 147 ? -38.043 -7.295 -9.096 1.00 60.44 ? 147 ARG A NE 1 ATOM 1152 C CZ . ARG A 1 147 ? -38.425 -6.198 -9.736 1.00 61.01 ? 147 ARG A CZ 1 ATOM 1153 N NH1 . ARG A 1 147 ? -37.525 -5.390 -10.263 1.00 61.40 ? 147 ARG A NH1 1 ATOM 1154 N NH2 . ARG A 1 147 ? -39.711 -5.907 -9.841 1.00 60.92 ? 147 ARG A NH2 1 ATOM 1155 N N . VAL A 1 148 ? -35.303 -9.626 -3.807 1.00 59.59 ? 148 VAL A N 1 ATOM 1156 C CA . VAL A 1 148 ? -34.820 -9.234 -2.487 1.00 60.37 ? 148 VAL A CA 1 ATOM 1157 C C . VAL A 1 148 ? -33.523 -8.426 -2.558 1.00 60.96 ? 148 VAL A C 1 ATOM 1158 O O . VAL A 1 148 ? -32.998 -8.186 -3.649 1.00 61.39 ? 148 VAL A O 1 ATOM 1159 C CB . VAL A 1 148 ? -34.588 -10.454 -1.555 1.00 60.43 ? 148 VAL A CB 1 ATOM 1160 C CG1 . VAL A 1 148 ? -35.850 -11.274 -1.433 1.00 60.35 ? 148 VAL A CG1 1 ATOM 1161 C CG2 . VAL A 1 148 ? -33.425 -11.306 -2.044 1.00 59.92 ? 148 VAL A CG2 1 ATOM 1162 N N . GLY A 1 149 ? -32.994 -8.033 -1.396 1.00 61.10 ? 149 GLY A N 1 ATOM 1163 C CA . GLY A 1 149 ? -31.819 -7.179 -1.357 1.00 61.48 ? 149 GLY A CA 1 ATOM 1164 C C . GLY A 1 149 ? -31.878 -6.075 -2.413 1.00 62.19 ? 149 GLY A C 1 ATOM 1165 O O . GLY A 1 149 ? -32.909 -5.846 -3.053 1.00 62.15 ? 149 GLY A O 1 ATOM 1166 N N . ALA A 1 150 ? -30.759 -5.384 -2.607 1.00 62.66 ? 150 ALA A N 1 ATOM 1167 C CA . ALA A 1 150 ? -30.710 -4.226 -3.477 1.00 62.64 ? 150 ALA A CA 1 ATOM 1168 C C . ALA A 1 150 ? -31.552 -4.425 -4.702 1.00 62.93 ? 150 ALA A C 1 ATOM 1169 O O . ALA A 1 150 ? -32.250 -3.534 -5.116 1.00 63.17 ? 150 ALA A O 1 ATOM 1170 C CB . ALA A 1 150 ? -29.311 -3.952 -3.865 1.00 62.55 ? 150 ALA A CB 1 ATOM 1171 N N . LEU A 1 151 ? -31.491 -5.602 -5.291 1.00 63.64 ? 151 LEU A N 1 ATOM 1172 C CA . LEU A 1 151 ? -32.216 -5.846 -6.529 1.00 64.34 ? 151 LEU A CA 1 ATOM 1173 C C . LEU A 1 151 ? -33.726 -5.658 -6.404 1.00 64.87 ? 151 LEU A C 1 ATOM 1174 O O . LEU A 1 151 ? -34.416 -5.444 -7.386 1.00 64.78 ? 151 LEU A O 1 ATOM 1175 C CB . LEU A 1 151 ? -31.883 -7.235 -7.070 1.00 64.17 ? 151 LEU A CB 1 ATOM 1176 C CG . LEU A 1 151 ? -30.502 -7.344 -7.732 1.00 63.66 ? 151 LEU A CG 1 ATOM 1177 C CD1 . LEU A 1 151 ? -30.279 -8.756 -8.192 1.00 63.54 ? 151 LEU A CD1 1 ATOM 1178 C CD2 . LEU A 1 151 ? -30.339 -6.385 -8.903 1.00 62.55 ? 151 LEU A CD2 1 ATOM 1179 N N . GLY A 1 152 ? -34.235 -5.731 -5.182 1.00 65.81 ? 152 GLY A N 1 ATOM 1180 C CA . GLY A 1 152 ? -35.680 -5.638 -4.939 1.00 66.43 ? 152 GLY A CA 1 ATOM 1181 C C . GLY A 1 152 ? -36.122 -4.443 -4.106 1.00 66.88 ? 152 GLY A C 1 ATOM 1182 O O . GLY A 1 152 ? -37.312 -4.124 -4.045 1.00 66.60 ? 152 GLY A O 1 ATOM 1183 N N . PHE A 1 153 ? -35.165 -3.762 -3.479 1.00 67.40 ? 153 PHE A N 1 ATOM 1184 C CA . PHE A 1 153 ? -35.487 -2.665 -2.589 1.00 67.89 ? 153 PHE A CA 1 ATOM 1185 C C . PHE A 1 153 ? -34.546 -1.500 -2.671 1.00 69.03 ? 153 PHE A C 1 ATOM 1186 O O . PHE A 1 153 ? -34.528 -0.660 -1.770 1.00 69.39 ? 153 PHE A O 1 ATOM 1187 C CB . PHE A 1 153 ? -35.557 -3.179 -1.166 1.00 67.39 ? 153 PHE A CB 1 ATOM 1188 C CG . PHE A 1 153 ? -36.594 -4.215 -0.996 1.00 66.00 ? 153 PHE A CG 1 ATOM 1189 C CD1 . PHE A 1 153 ? -37.930 -3.877 -1.106 1.00 65.33 ? 153 PHE A CD1 1 ATOM 1190 C CD2 . PHE A 1 153 ? -36.254 -5.533 -0.802 1.00 64.59 ? 153 PHE A CD2 1 ATOM 1191 C CE1 . PHE A 1 153 ? -38.909 -4.826 -0.987 1.00 64.26 ? 153 PHE A CE1 1 ATOM 1192 C CE2 . PHE A 1 153 ? -37.231 -6.486 -0.677 1.00 64.17 ? 153 PHE A CE2 1 ATOM 1193 C CZ . PHE A 1 153 ? -38.562 -6.129 -0.776 1.00 63.86 ? 153 PHE A CZ 1 ATOM 1194 N N . LEU A 1 154 ? -33.768 -1.444 -3.748 1.00 70.34 ? 154 LEU A N 1 ATOM 1195 C CA . LEU A 1 154 ? -32.861 -0.337 -3.962 1.00 71.45 ? 154 LEU A CA 1 ATOM 1196 C C . LEU A 1 154 ? -33.772 0.835 -4.098 1.00 72.40 ? 154 LEU A C 1 ATOM 1197 O O . LEU A 1 154 ? -34.747 0.787 -4.828 1.00 72.20 ? 154 LEU A O 1 ATOM 1198 C CB . LEU A 1 154 ? -32.053 -0.506 -5.244 1.00 71.51 ? 154 LEU A CB 1 ATOM 1199 C CG . LEU A 1 154 ? -31.137 0.678 -5.552 1.00 71.50 ? 154 LEU A CG 1 ATOM 1200 C CD1 . LEU A 1 154 ? -29.831 0.473 -4.804 1.00 71.98 ? 154 LEU A CD1 1 ATOM 1201 C CD2 . LEU A 1 154 ? -30.907 0.869 -7.036 1.00 69.45 ? 154 LEU A CD2 1 ATOM 1202 N N . ALA A 1 155 ? -33.472 1.885 -3.368 1.00 74.13 ? 155 ALA A N 1 ATOM 1203 C CA . ALA A 1 155 ? -34.394 2.977 -3.295 1.00 76.10 ? 155 ALA A CA 1 ATOM 1204 C C . ALA A 1 155 ? -33.700 4.264 -3.650 1.00 77.59 ? 155 ALA A C 1 ATOM 1205 O O . ALA A 1 155 ? -32.729 4.670 -3.002 1.00 77.97 ? 155 ALA A O 1 ATOM 1206 C CB . ALA A 1 155 ? -34.989 3.067 -1.896 1.00 75.91 ? 155 ALA A CB 1 ATOM 1207 N N . LEU A 1 156 ? -34.208 4.915 -4.680 1.00 79.29 ? 156 LEU A N 1 ATOM 1208 C CA . LEU A 1 156 ? -33.808 6.276 -4.960 1.00 81.20 ? 156 LEU A CA 1 ATOM 1209 C C . LEU A 1 156 ? -35.083 7.120 -5.030 1.00 82.43 ? 156 LEU A C 1 ATOM 1210 O O . LEU A 1 156 ? -35.675 7.296 -6.096 1.00 82.89 ? 156 LEU A O 1 ATOM 1211 C CB . LEU A 1 156 ? -33.018 6.323 -6.261 1.00 81.40 ? 156 LEU A CB 1 ATOM 1212 C CG . LEU A 1 156 ? -31.886 7.337 -6.345 1.00 81.74 ? 156 LEU A CG 1 ATOM 1213 C CD1 . LEU A 1 156 ? -30.849 7.097 -5.273 1.00 80.95 ? 156 LEU A CD1 1 ATOM 1214 C CD2 . LEU A 1 156 ? -31.277 7.244 -7.724 1.00 82.77 ? 156 LEU A CD2 1 ATOM 1215 N N . PRO A 1 157 ? -35.498 7.660 -3.880 1.00 83.52 ? 157 PRO A N 1 ATOM 1216 C CA . PRO A 1 157 ? -36.864 8.112 -3.580 1.00 84.07 ? 157 PRO A CA 1 ATOM 1217 C C . PRO A 1 157 ? -37.520 8.926 -4.686 1.00 84.36 ? 157 PRO A C 1 ATOM 1218 O O . PRO A 1 157 ? -37.031 9.999 -5.030 1.00 84.42 ? 157 PRO A O 1 ATOM 1219 C CB . PRO A 1 157 ? -36.675 8.997 -2.346 1.00 84.42 ? 157 PRO A CB 1 ATOM 1220 C CG . PRO A 1 157 ? -35.383 8.526 -1.716 1.00 84.41 ? 157 PRO A CG 1 ATOM 1221 C CD . PRO A 1 157 ? -34.521 8.129 -2.882 1.00 83.87 ? 157 PRO A CD 1 ATOM 1222 N N . GLY A 1 158 ? -38.627 8.427 -5.225 1.00 84.51 ? 158 GLY A N 1 ATOM 1223 C CA . GLY A 1 158 ? -39.385 9.187 -6.213 1.00 84.92 ? 158 GLY A CA 1 ATOM 1224 C C . GLY A 1 158 ? -38.814 9.120 -7.620 1.00 85.20 ? 158 GLY A C 1 ATOM 1225 O O . GLY A 1 158 ? -39.454 9.551 -8.585 1.00 85.19 ? 158 GLY A O 1 ATOM 1226 N N . ASN A 1 159 ? -37.607 8.567 -7.727 1.00 85.20 ? 159 ASN A N 1 ATOM 1227 C CA . ASN A 1 159 ? -36.929 8.335 -8.991 1.00 85.08 ? 159 ASN A CA 1 ATOM 1228 C C . ASN A 1 159 ? -37.377 7.021 -9.630 1.00 84.75 ? 159 ASN A C 1 ATOM 1229 O O . ASN A 1 159 ? -36.984 5.949 -9.167 1.00 84.83 ? 159 ASN A O 1 ATOM 1230 C CB . ASN A 1 159 ? -35.450 8.250 -8.695 1.00 85.18 ? 159 ASN A CB 1 ATOM 1231 C CG . ASN A 1 159 ? -34.610 8.519 -9.895 1.00 86.26 ? 159 ASN A CG 1 ATOM 1232 O OD1 . ASN A 1 159 ? -34.978 8.170 -11.032 1.00 86.91 ? 159 ASN A OD1 1 ATOM 1233 N ND2 . ASN A 1 159 ? -33.456 9.147 -9.662 1.00 86.83 ? 159 ASN A ND2 1 ATOM 1234 N N . PRO A 1 160 ? -38.181 7.099 -10.704 1.00 84.31 ? 160 PRO A N 1 ATOM 1235 C CA . PRO A 1 160 ? -38.892 5.933 -11.250 1.00 83.93 ? 160 PRO A CA 1 ATOM 1236 C C . PRO A 1 160 ? -37.943 4.852 -11.717 1.00 83.67 ? 160 PRO A C 1 ATOM 1237 O O . PRO A 1 160 ? -38.367 3.733 -12.021 1.00 83.62 ? 160 PRO A O 1 ATOM 1238 C CB . PRO A 1 160 ? -39.667 6.499 -12.437 1.00 83.72 ? 160 PRO A CB 1 ATOM 1239 C CG . PRO A 1 160 ? -39.724 7.959 -12.190 1.00 84.48 ? 160 PRO A CG 1 ATOM 1240 C CD . PRO A 1 160 ? -38.451 8.317 -11.473 1.00 84.28 ? 160 PRO A CD 1 ATOM 1241 N N . GLU A 1 161 ? -36.661 5.186 -11.759 1.00 83.32 ? 161 GLU A N 1 ATOM 1242 C CA . GLU A 1 161 ? -35.640 4.227 -12.165 1.00 83.10 ? 161 GLU A CA 1 ATOM 1243 C C . GLU A 1 161 ? -35.300 3.249 -11.056 1.00 81.80 ? 161 GLU A C 1 ATOM 1244 O O . GLU A 1 161 ? -35.058 2.066 -11.312 1.00 81.97 ? 161 GLU A O 1 ATOM 1245 C CB . GLU A 1 161 ? -34.378 4.966 -12.604 1.00 83.73 ? 161 GLU A CB 1 ATOM 1246 C CG . GLU A 1 161 ? -34.595 5.856 -13.816 1.00 86.67 ? 161 GLU A CG 1 ATOM 1247 C CD . GLU A 1 161 ? -35.078 5.086 -15.051 1.00 89.80 ? 161 GLU A CD 1 ATOM 1248 O OE1 . GLU A 1 161 ? -35.438 3.879 -14.942 1.00 90.29 ? 161 GLU A OE1 1 ATOM 1249 O OE2 . GLU A 1 161 ? -35.093 5.710 -16.134 1.00 91.32 ? 161 GLU A OE2 1 ATOM 1250 N N . ALA A 1 162 ? -35.264 3.770 -9.834 1.00 80.13 ? 162 ALA A N 1 ATOM 1251 C CA . ALA A 1 162 ? -35.076 2.973 -8.650 1.00 78.33 ? 162 ALA A CA 1 ATOM 1252 C C . ALA A 1 162 ? -36.009 3.531 -7.620 1.00 77.11 ? 162 ALA A C 1 ATOM 1253 O O . ALA A 1 162 ? -35.562 4.164 -6.678 1.00 77.17 ? 162 ALA A O 1 ATOM 1254 C CB . ALA A 1 162 ? -33.667 3.084 -8.171 1.00 78.35 ? 162 ALA A CB 1 ATOM 1255 N N . PRO A 1 163 ? -37.317 3.288 -7.785 1.00 75.70 ? 163 PRO A N 1 ATOM 1256 C CA . PRO A 1 163 ? -38.311 3.880 -6.921 1.00 74.69 ? 163 PRO A CA 1 ATOM 1257 C C . PRO A 1 163 ? -38.432 3.204 -5.551 1.00 73.59 ? 163 PRO A C 1 ATOM 1258 O O . PRO A 1 163 ? -39.169 3.703 -4.711 1.00 73.89 ? 163 PRO A O 1 ATOM 1259 C CB . PRO A 1 163 ? -39.592 3.681 -7.716 1.00 74.59 ? 163 PRO A CB 1 ATOM 1260 C CG . PRO A 1 163 ? -39.379 2.404 -8.377 1.00 74.89 ? 163 PRO A CG 1 ATOM 1261 C CD . PRO A 1 163 ? -37.935 2.387 -8.765 1.00 75.44 ? 163 PRO A CD 1 ATOM 1262 N N . GLY A 1 164 ? -37.722 2.097 -5.324 1.00 72.13 ? 164 GLY A N 1 ATOM 1263 C CA . GLY A 1 164 ? -37.815 1.343 -4.061 1.00 70.10 ? 164 GLY A CA 1 ATOM 1264 C C . GLY A 1 164 ? -39.025 0.418 -3.958 1.00 69.01 ? 164 GLY A C 1 ATOM 1265 O O . GLY A 1 164 ? -39.999 0.557 -4.700 1.00 69.03 ? 164 GLY A O 1 ATOM 1266 N N . ASN A 1 165 ? -38.977 -0.538 -3.040 1.00 67.76 ? 165 ASN A N 1 ATOM 1267 C CA . ASN A 1 165 ? -40.106 -1.453 -2.833 1.00 66.71 ? 165 ASN A CA 1 ATOM 1268 C C . ASN A 1 165 ? -40.482 -2.293 -4.060 1.00 66.12 ? 165 ASN A C 1 ATOM 1269 O O . ASN A 1 165 ? -41.632 -2.680 -4.222 1.00 66.39 ? 165 ASN A O 1 ATOM 1270 C CB . ASN A 1 165 ? -41.356 -0.690 -2.393 1.00 66.41 ? 165 ASN A CB 1 ATOM 1271 C CG . ASN A 1 165 ? -41.165 0.079 -1.117 1.00 66.12 ? 165 ASN A CG 1 ATOM 1272 O OD1 . ASN A 1 165 ? -40.381 -0.293 -0.255 1.00 65.48 ? 165 ASN A OD1 1 ATOM 1273 N ND2 . ASN A 1 165 ? -41.900 1.171 -0.989 1.00 66.55 ? 165 ASN A ND2 1 ATOM 1274 N N . MET A 1 166 ? -39.534 -2.580 -4.932 1.00 65.09 ? 166 MET A N 1 ATOM 1275 C CA . MET A 1 166 ? -39.868 -3.320 -6.129 1.00 64.09 ? 166 MET A CA 1 ATOM 1276 C C . MET A 1 166 ? -40.323 -4.726 -5.784 1.00 63.79 ? 166 MET A C 1 ATOM 1277 O O . MET A 1 166 ? -41.239 -5.260 -6.387 1.00 63.60 ? 166 MET A O 1 ATOM 1278 C CB . MET A 1 166 ? -38.664 -3.399 -7.039 1.00 64.07 ? 166 MET A CB 1 ATOM 1279 C CG . MET A 1 166 ? -38.312 -2.111 -7.703 1.00 63.22 ? 166 MET A CG 1 ATOM 1280 S SD . MET A 1 166 ? -37.329 -1.022 -6.673 1.00 62.52 ? 166 MET A SD 1 ATOM 1281 C CE . MET A 1 166 ? -35.859 -1.975 -6.274 1.00 61.04 ? 166 MET A CE 1 ATOM 1282 N N . GLY A 1 167 ? -39.660 -5.322 -4.803 1.00 63.49 ? 167 GLY A N 1 ATOM 1283 C CA . GLY A 1 167 ? -40.007 -6.656 -4.335 1.00 63.09 ? 167 GLY A CA 1 ATOM 1284 C C . GLY A 1 167 ? -41.421 -6.699 -3.818 1.00 62.63 ? 167 GLY A C 1 ATOM 1285 O O . GLY A 1 167 ? -42.144 -7.672 -4.037 1.00 62.53 ? 167 GLY A O 1 ATOM 1286 N N . LEU A 1 168 ? -41.814 -5.626 -3.139 1.00 62.21 ? 168 LEU A N 1 ATOM 1287 C CA . LEU A 1 168 ? -43.164 -5.499 -2.606 1.00 61.76 ? 168 LEU A CA 1 ATOM 1288 C C . LEU A 1 168 ? -44.174 -5.444 -3.740 1.00 61.76 ? 168 LEU A C 1 ATOM 1289 O O . LEU A 1 168 ? -45.230 -6.075 -3.693 1.00 61.81 ? 168 LEU A O 1 ATOM 1290 C CB . LEU A 1 168 ? -43.268 -4.263 -1.731 1.00 61.47 ? 168 LEU A CB 1 ATOM 1291 C CG . LEU A 1 168 ? -42.809 -4.540 -0.306 1.00 60.82 ? 168 LEU A CG 1 ATOM 1292 C CD1 . LEU A 1 168 ? -42.911 -3.325 0.543 1.00 60.21 ? 168 LEU A CD1 1 ATOM 1293 C CD2 . LEU A 1 168 ? -43.660 -5.635 0.265 1.00 60.27 ? 168 LEU A CD2 1 ATOM 1294 N N . PHE A 1 169 ? -43.826 -4.709 -4.781 1.00 61.45 ? 169 PHE A N 1 ATOM 1295 C CA . PHE A 1 169 ? -44.672 -4.651 -5.936 1.00 61.22 ? 169 PHE A CA 1 ATOM 1296 C C . PHE A 1 169 ? -44.743 -5.990 -6.630 1.00 61.26 ? 169 PHE A C 1 ATOM 1297 O O . PHE A 1 169 ? -45.782 -6.338 -7.186 1.00 61.44 ? 169 PHE A O 1 ATOM 1298 C CB . PHE A 1 169 ? -44.189 -3.559 -6.879 1.00 61.47 ? 169 PHE A CB 1 ATOM 1299 C CG . PHE A 1 169 ? -44.707 -2.212 -6.518 1.00 61.49 ? 169 PHE A CG 1 ATOM 1300 C CD1 . PHE A 1 169 ? -43.899 -1.285 -5.896 1.00 60.37 ? 169 PHE A CD1 1 ATOM 1301 C CD2 . PHE A 1 169 ? -46.039 -1.896 -6.753 1.00 61.61 ? 169 PHE A CD2 1 ATOM 1302 C CE1 . PHE A 1 169 ? -44.407 -0.050 -5.531 1.00 61.35 ? 169 PHE A CE1 1 ATOM 1303 C CE2 . PHE A 1 169 ? -46.544 -0.670 -6.402 1.00 61.26 ? 169 PHE A CE2 1 ATOM 1304 C CZ . PHE A 1 169 ? -45.726 0.256 -5.787 1.00 61.16 ? 169 PHE A CZ 1 ATOM 1305 N N . ASP A 1 170 ? -43.642 -6.737 -6.614 1.00 61.23 ? 170 ASP A N 1 ATOM 1306 C CA . ASP A 1 170 ? -43.665 -8.089 -7.140 1.00 61.25 ? 170 ASP A CA 1 ATOM 1307 C C . ASP A 1 170 ? -44.805 -8.813 -6.458 1.00 61.33 ? 170 ASP A C 1 ATOM 1308 O O . ASP A 1 170 ? -45.778 -9.218 -7.091 1.00 61.26 ? 170 ASP A O 1 ATOM 1309 C CB . ASP A 1 170 ? -42.374 -8.816 -6.829 1.00 61.36 ? 170 ASP A CB 1 ATOM 1310 C CG . ASP A 1 170 ? -41.219 -8.292 -7.611 1.00 62.00 ? 170 ASP A CG 1 ATOM 1311 O OD1 . ASP A 1 170 ? -41.446 -7.756 -8.714 1.00 63.17 ? 170 ASP A OD1 1 ATOM 1312 O OD2 . ASP A 1 170 ? -40.076 -8.429 -7.129 1.00 61.66 ? 170 ASP A OD2 1 ATOM 1313 N N . GLN A 1 171 ? -44.689 -8.949 -5.142 1.00 61.31 ? 171 GLN A N 1 ATOM 1314 C CA . GLN A 1 171 ? -45.725 -9.590 -4.342 1.00 61.26 ? 171 GLN A CA 1 ATOM 1315 C C . GLN A 1 171 ? -47.104 -9.149 -4.789 1.00 61.24 ? 171 GLN A C 1 ATOM 1316 O O . GLN A 1 171 ? -47.972 -9.973 -5.070 1.00 61.26 ? 171 GLN A O 1 ATOM 1317 C CB . GLN A 1 171 ? -45.530 -9.263 -2.866 1.00 61.28 ? 171 GLN A CB 1 ATOM 1318 C CG . GLN A 1 171 ? -44.168 -9.653 -2.355 1.00 61.93 ? 171 GLN A CG 1 ATOM 1319 C CD . GLN A 1 171 ? -44.031 -9.465 -0.884 1.00 62.14 ? 171 GLN A CD 1 ATOM 1320 O OE1 . GLN A 1 171 ? -45.012 -9.453 -0.167 1.00 64.12 ? 171 GLN A OE1 1 ATOM 1321 N NE2 . GLN A 1 171 ? -42.814 -9.308 -0.420 1.00 61.15 ? 171 GLN A NE2 1 ATOM 1322 N N . GLN A 1 172 ? -47.299 -7.839 -4.867 1.00 61.13 ? 172 GLN A N 1 ATOM 1323 C CA . GLN A 1 172 ? -48.581 -7.303 -5.269 1.00 61.14 ? 172 GLN A CA 1 ATOM 1324 C C . GLN A 1 172 ? -49.022 -7.784 -6.640 1.00 61.30 ? 172 GLN A C 1 ATOM 1325 O O . GLN A 1 172 ? -50.190 -8.101 -6.852 1.00 60.91 ? 172 GLN A O 1 ATOM 1326 C CB . GLN A 1 172 ? -48.545 -5.789 -5.251 1.00 61.22 ? 172 GLN A CB 1 ATOM 1327 C CG . GLN A 1 172 ? -49.885 -5.161 -5.540 1.00 60.90 ? 172 GLN A CG 1 ATOM 1328 C CD . GLN A 1 172 ? -49.892 -3.695 -5.238 1.00 61.32 ? 172 GLN A CD 1 ATOM 1329 O OE1 . GLN A 1 172 ? -50.257 -3.281 -4.142 1.00 60.60 ? 172 GLN A OE1 1 ATOM 1330 N NE2 . GLN A 1 172 ? -49.461 -2.893 -6.202 1.00 62.20 ? 172 GLN A NE2 1 ATOM 1331 N N . LEU A 1 173 ? -48.096 -7.827 -7.584 1.00 61.63 ? 173 LEU A N 1 ATOM 1332 C CA . LEU A 1 173 ? -48.462 -8.281 -8.907 1.00 62.33 ? 173 LEU A CA 1 ATOM 1333 C C . LEU A 1 173 ? -48.862 -9.754 -8.828 1.00 62.67 ? 173 LEU A C 1 ATOM 1334 O O . LEU A 1 173 ? -49.779 -10.204 -9.531 1.00 62.82 ? 173 LEU A O 1 ATOM 1335 C CB . LEU A 1 173 ? -47.330 -8.040 -9.909 1.00 62.51 ? 173 LEU A CB 1 ATOM 1336 C CG . LEU A 1 173 ? -47.712 -8.193 -11.385 1.00 62.37 ? 173 LEU A CG 1 ATOM 1337 C CD1 . LEU A 1 173 ? -49.065 -7.571 -11.595 1.00 62.33 ? 173 LEU A CD1 1 ATOM 1338 C CD2 . LEU A 1 173 ? -46.681 -7.587 -12.317 1.00 61.55 ? 173 LEU A CD2 1 ATOM 1339 N N . ALA A 1 174 ? -48.198 -10.494 -7.943 1.00 62.77 ? 174 ALA A N 1 ATOM 1340 C CA . ALA A 1 174 ? -48.570 -11.874 -7.705 1.00 63.06 ? 174 ALA A CA 1 ATOM 1341 C C . ALA A 1 174 ? -50.007 -11.941 -7.206 1.00 63.62 ? 174 ALA A C 1 ATOM 1342 O O . ALA A 1 174 ? -50.768 -12.814 -7.610 1.00 63.79 ? 174 ALA A O 1 ATOM 1343 C CB . ALA A 1 174 ? -47.633 -12.511 -6.721 1.00 62.84 ? 174 ALA A CB 1 ATOM 1344 N N . LEU A 1 175 ? -50.388 -11.006 -6.344 1.00 64.08 ? 175 LEU A N 1 ATOM 1345 C CA . LEU A 1 175 ? -51.752 -10.972 -5.854 1.00 64.63 ? 175 LEU A CA 1 ATOM 1346 C C . LEU A 1 175 ? -52.747 -10.675 -6.965 1.00 65.08 ? 175 LEU A C 1 ATOM 1347 O O . LEU A 1 175 ? -53.770 -11.339 -7.063 1.00 64.85 ? 175 LEU A O 1 ATOM 1348 C CB . LEU A 1 175 ? -51.898 -9.949 -4.743 1.00 64.79 ? 175 LEU A CB 1 ATOM 1349 C CG . LEU A 1 175 ? -50.935 -10.103 -3.575 1.00 64.48 ? 175 LEU A CG 1 ATOM 1350 C CD1 . LEU A 1 175 ? -51.333 -9.151 -2.454 1.00 63.77 ? 175 LEU A CD1 1 ATOM 1351 C CD2 . LEU A 1 175 ? -50.909 -11.551 -3.117 1.00 63.44 ? 175 LEU A CD2 1 ATOM 1352 N N . GLN A 1 176 ? -52.457 -9.668 -7.789 1.00 66.05 ? 176 GLN A N 1 ATOM 1353 C CA . GLN A 1 176 ? -53.278 -9.383 -8.983 1.00 67.12 ? 176 GLN A CA 1 ATOM 1354 C C . GLN A 1 176 ? -53.423 -10.605 -9.842 1.00 66.70 ? 176 GLN A C 1 ATOM 1355 O O . GLN A 1 176 ? -54.472 -10.836 -10.434 1.00 66.54 ? 176 GLN A O 1 ATOM 1356 C CB . GLN A 1 176 ? -52.652 -8.311 -9.862 1.00 67.47 ? 176 GLN A CB 1 ATOM 1357 C CG . GLN A 1 176 ? -53.393 -7.009 -9.901 1.00 70.88 ? 176 GLN A CG 1 ATOM 1358 C CD . GLN A 1 176 ? -52.453 -5.841 -10.221 1.00 76.05 ? 176 GLN A CD 1 ATOM 1359 O OE1 . GLN A 1 176 ? -51.686 -5.364 -9.361 1.00 77.78 ? 176 GLN A OE1 1 ATOM 1360 N NE2 . GLN A 1 176 ? -52.504 -5.380 -11.466 1.00 77.48 ? 176 GLN A NE2 1 ATOM 1361 N N . TRP A 1 177 ? -52.346 -11.367 -9.944 1.00 66.53 ? 177 TRP A N 1 ATOM 1362 C CA . TRP A 1 177 ? -52.398 -12.543 -10.761 1.00 66.69 ? 177 TRP A CA 1 ATOM 1363 C C . TRP A 1 177 ? -53.442 -13.474 -10.227 1.00 66.37 ? 177 TRP A C 1 ATOM 1364 O O . TRP A 1 177 ? -54.340 -13.869 -10.948 1.00 66.63 ? 177 TRP A O 1 ATOM 1365 C CB . TRP A 1 177 ? -51.069 -13.261 -10.797 1.00 66.99 ? 177 TRP A CB 1 ATOM 1366 C CG . TRP A 1 177 ? -51.088 -14.374 -11.797 1.00 67.55 ? 177 TRP A CG 1 ATOM 1367 C CD1 . TRP A 1 177 ? -50.767 -14.288 -13.107 1.00 67.02 ? 177 TRP A CD1 1 ATOM 1368 C CD2 . TRP A 1 177 ? -51.475 -15.736 -11.561 1.00 68.11 ? 177 TRP A CD2 1 ATOM 1369 N NE1 . TRP A 1 177 ? -50.916 -15.505 -13.700 1.00 67.35 ? 177 TRP A NE1 1 ATOM 1370 C CE2 . TRP A 1 177 ? -51.344 -16.414 -12.772 1.00 67.52 ? 177 TRP A CE2 1 ATOM 1371 C CE3 . TRP A 1 177 ? -51.905 -16.447 -10.433 1.00 69.13 ? 177 TRP A CE3 1 ATOM 1372 C CZ2 . TRP A 1 177 ? -51.629 -17.763 -12.902 1.00 68.10 ? 177 TRP A CZ2 1 ATOM 1373 C CZ3 . TRP A 1 177 ? -52.199 -17.790 -10.565 1.00 69.27 ? 177 TRP A CZ3 1 ATOM 1374 C CH2 . TRP A 1 177 ? -52.060 -18.433 -11.792 1.00 69.15 ? 177 TRP A CH2 1 ATOM 1375 N N . VAL A 1 178 ? -53.316 -13.834 -8.959 1.00 66.06 ? 178 VAL A N 1 ATOM 1376 C CA . VAL A 1 178 ? -54.293 -14.698 -8.336 1.00 65.55 ? 178 VAL A CA 1 ATOM 1377 C C . VAL A 1 178 ? -55.672 -14.107 -8.550 1.00 65.80 ? 178 VAL A C 1 ATOM 1378 O O . VAL A 1 178 ? -56.619 -14.827 -8.827 1.00 65.85 ? 178 VAL A O 1 ATOM 1379 C CB . VAL A 1 178 ? -54.037 -14.870 -6.841 1.00 65.08 ? 178 VAL A CB 1 ATOM 1380 C CG1 . VAL A 1 178 ? -55.036 -15.808 -6.270 1.00 64.58 ? 178 VAL A CG1 1 ATOM 1381 C CG2 . VAL A 1 178 ? -52.667 -15.402 -6.619 1.00 64.60 ? 178 VAL A CG2 1 ATOM 1382 N N . GLN A 1 179 ? -55.780 -12.787 -8.459 1.00 66.18 ? 179 GLN A N 1 ATOM 1383 C CA . GLN A 1 179 ? -57.075 -12.123 -8.635 1.00 66.83 ? 179 GLN A CA 1 ATOM 1384 C C . GLN A 1 179 ? -57.711 -12.396 -9.995 1.00 67.42 ? 179 GLN A C 1 ATOM 1385 O O . GLN A 1 179 ? -58.906 -12.649 -10.095 1.00 67.22 ? 179 GLN A O 1 ATOM 1386 C CB . GLN A 1 179 ? -56.965 -10.611 -8.404 1.00 66.60 ? 179 GLN A CB 1 ATOM 1387 C CG . GLN A 1 179 ? -57.142 -10.218 -6.958 1.00 66.05 ? 179 GLN A CG 1 ATOM 1388 C CD . GLN A 1 179 ? -58.325 -10.904 -6.330 1.00 65.07 ? 179 GLN A CD 1 ATOM 1389 O OE1 . GLN A 1 179 ? -59.451 -10.490 -6.532 1.00 65.55 ? 179 GLN A OE1 1 ATOM 1390 N NE2 . GLN A 1 179 ? -58.078 -11.959 -5.566 1.00 64.04 ? 179 GLN A NE2 1 ATOM 1391 N N . LYS A 1 180 ? -56.898 -12.351 -11.038 1.00 68.31 ? 180 LYS A N 1 ATOM 1392 C CA . LYS A 1 180 ? -57.406 -12.525 -12.373 1.00 68.98 ? 180 LYS A CA 1 ATOM 1393 C C . LYS A 1 180 ? -57.542 -13.992 -12.766 1.00 69.21 ? 180 LYS A C 1 ATOM 1394 O O . LYS A 1 180 ? -58.322 -14.301 -13.658 1.00 69.76 ? 180 LYS A O 1 ATOM 1395 C CB . LYS A 1 180 ? -56.546 -11.755 -13.382 1.00 69.12 ? 180 LYS A CB 1 ATOM 1396 C CG . LYS A 1 180 ? -56.904 -10.284 -13.475 1.00 70.82 ? 180 LYS A CG 1 ATOM 1397 C CD . LYS A 1 180 ? -55.910 -9.484 -14.304 1.00 73.93 ? 180 LYS A CD 1 ATOM 1398 C CE . LYS A 1 180 ? -56.566 -8.197 -14.814 1.00 76.38 ? 180 LYS A CE 1 ATOM 1399 N NZ . LYS A 1 180 ? -55.631 -7.278 -15.546 1.00 77.20 ? 180 LYS A NZ 1 ATOM 1400 N N . ASN A 1 181 ? -56.827 -14.904 -12.109 1.00 69.26 ? 181 ASN A N 1 ATOM 1401 C CA . ASN A 1 181 ? -56.709 -16.257 -12.660 1.00 69.35 ? 181 ASN A CA 1 ATOM 1402 C C . ASN A 1 181 ? -57.172 -17.395 -11.792 1.00 69.03 ? 181 ASN A C 1 ATOM 1403 O O . ASN A 1 181 ? -57.560 -18.443 -12.296 1.00 69.45 ? 181 ASN A O 1 ATOM 1404 C CB . ASN A 1 181 ? -55.270 -16.537 -13.084 1.00 69.62 ? 181 ASN A CB 1 ATOM 1405 C CG . ASN A 1 181 ? -54.788 -15.592 -14.149 1.00 70.97 ? 181 ASN A CG 1 ATOM 1406 O OD1 . ASN A 1 181 ? -55.337 -15.560 -15.247 1.00 72.65 ? 181 ASN A OD1 1 ATOM 1407 N ND2 . ASN A 1 181 ? -53.750 -14.813 -13.837 1.00 72.66 ? 181 ASN A ND2 1 ATOM 1408 N N . ILE A 1 182 ? -57.102 -17.222 -10.486 1.00 68.40 ? 182 ILE A N 1 ATOM 1409 C CA . ILE A 1 182 ? -57.254 -18.378 -9.619 1.00 67.74 ? 182 ILE A CA 1 ATOM 1410 C C . ILE A 1 182 ? -58.585 -19.066 -9.850 1.00 67.65 ? 182 ILE A C 1 ATOM 1411 O O . ILE A 1 182 ? -58.697 -20.278 -9.695 1.00 67.52 ? 182 ILE A O 1 ATOM 1412 C CB . ILE A 1 182 ? -57.070 -18.040 -8.128 1.00 67.59 ? 182 ILE A CB 1 ATOM 1413 C CG1 . ILE A 1 182 ? -56.634 -19.284 -7.364 1.00 66.84 ? 182 ILE A CG1 1 ATOM 1414 C CG2 . ILE A 1 182 ? -58.339 -17.433 -7.534 1.00 67.31 ? 182 ILE A CG2 1 ATOM 1415 C CD1 . ILE A 1 182 ? -55.249 -19.763 -7.702 1.00 65.43 ? 182 ILE A CD1 1 ATOM 1416 N N . ALA A 1 183 ? -59.594 -18.294 -10.237 1.00 67.52 ? 183 ALA A N 1 ATOM 1417 C CA . ALA A 1 183 ? -60.893 -18.880 -10.521 1.00 67.35 ? 183 ALA A CA 1 ATOM 1418 C C . ALA A 1 183 ? -60.766 -20.073 -11.492 1.00 67.50 ? 183 ALA A C 1 ATOM 1419 O O . ALA A 1 183 ? -61.337 -21.135 -11.246 1.00 67.55 ? 183 ALA A O 1 ATOM 1420 C CB . ALA A 1 183 ? -61.847 -17.827 -11.034 1.00 66.94 ? 183 ALA A CB 1 ATOM 1421 N N . ALA A 1 184 ? -59.990 -19.910 -12.565 1.00 67.48 ? 184 ALA A N 1 ATOM 1422 C CA . ALA A 1 184 ? -59.730 -20.996 -13.510 1.00 67.35 ? 184 ALA A CA 1 ATOM 1423 C C . ALA A 1 184 ? -59.259 -22.291 -12.853 1.00 67.56 ? 184 ALA A C 1 ATOM 1424 O O . ALA A 1 184 ? -59.428 -23.367 -13.412 1.00 67.85 ? 184 ALA A O 1 ATOM 1425 C CB . ALA A 1 184 ? -58.720 -20.565 -14.520 1.00 67.35 ? 184 ALA A CB 1 ATOM 1426 N N . PHE A 1 185 ? -58.639 -22.198 -11.685 1.00 67.45 ? 185 PHE A N 1 ATOM 1427 C CA . PHE A 1 185 ? -58.222 -23.398 -10.967 1.00 66.95 ? 185 PHE A CA 1 ATOM 1428 C C . PHE A 1 185 ? -59.259 -23.741 -9.922 1.00 66.87 ? 185 PHE A C 1 ATOM 1429 O O . PHE A 1 185 ? -59.081 -24.681 -9.147 1.00 67.26 ? 185 PHE A O 1 ATOM 1430 C CB . PHE A 1 185 ? -56.874 -23.184 -10.279 1.00 66.82 ? 185 PHE A CB 1 ATOM 1431 C CG . PHE A 1 185 ? -55.759 -22.793 -11.215 1.00 66.64 ? 185 PHE A CG 1 ATOM 1432 C CD1 . PHE A 1 185 ? -55.782 -21.573 -11.881 1.00 66.83 ? 185 PHE A CD1 1 ATOM 1433 C CD2 . PHE A 1 185 ? -54.678 -23.637 -11.409 1.00 66.34 ? 185 PHE A CD2 1 ATOM 1434 C CE1 . PHE A 1 185 ? -54.753 -21.205 -12.728 1.00 67.15 ? 185 PHE A CE1 1 ATOM 1435 C CE2 . PHE A 1 185 ? -53.665 -23.292 -12.254 1.00 66.49 ? 185 PHE A CE2 1 ATOM 1436 C CZ . PHE A 1 185 ? -53.695 -22.065 -12.917 1.00 67.27 ? 185 PHE A CZ 1 ATOM 1437 N N . GLY A 1 186 ? -60.341 -22.975 -9.895 1.00 66.48 ? 186 GLY A N 1 ATOM 1438 C CA . GLY A 1 186 ? -61.400 -23.196 -8.923 1.00 66.42 ? 186 GLY A CA 1 ATOM 1439 C C . GLY A 1 186 ? -61.151 -22.448 -7.630 1.00 66.22 ? 186 GLY A C 1 ATOM 1440 O O . GLY A 1 186 ? -61.732 -22.757 -6.590 1.00 66.18 ? 186 GLY A O 1 ATOM 1441 N N . GLY A 1 187 ? -60.272 -21.463 -7.682 1.00 65.99 ? 187 GLY A N 1 ATOM 1442 C CA . GLY A 1 187 ? -59.992 -20.699 -6.487 1.00 65.88 ? 187 GLY A CA 1 ATOM 1443 C C . GLY A 1 187 ? -61.062 -19.653 -6.384 1.00 65.76 ? 187 GLY A C 1 ATOM 1444 O O . GLY A 1 187 ? -61.625 -19.270 -7.388 1.00 65.86 ? 187 GLY A O 1 ATOM 1445 N N . ASN A 1 188 ? -61.373 -19.204 -5.179 1.00 65.52 ? 188 ASN A N 1 ATOM 1446 C CA . ASN A 1 188 ? -62.295 -18.090 -5.049 1.00 65.29 ? 188 ASN A CA 1 ATOM 1447 C C . ASN A 1 188 ? -61.580 -16.788 -4.727 1.00 65.30 ? 188 ASN A C 1 ATOM 1448 O O . ASN A 1 188 ? -61.196 -16.538 -3.586 1.00 65.39 ? 188 ASN A O 1 ATOM 1449 C CB . ASN A 1 188 ? -63.355 -18.370 -4.002 1.00 65.31 ? 188 ASN A CB 1 ATOM 1450 C CG . ASN A 1 188 ? -64.196 -17.162 -3.708 1.00 65.58 ? 188 ASN A CG 1 ATOM 1451 O OD1 . ASN A 1 188 ? -64.136 -16.167 -4.424 1.00 65.25 ? 188 ASN A OD1 1 ATOM 1452 N ND2 . ASN A 1 188 ? -64.974 -17.227 -2.636 1.00 66.92 ? 188 ASN A ND2 1 ATOM 1453 N N . PRO A 1 189 ? -61.405 -15.937 -5.739 1.00 65.25 ? 189 PRO A N 1 ATOM 1454 C CA . PRO A 1 189 ? -60.667 -14.707 -5.543 1.00 65.39 ? 189 PRO A CA 1 ATOM 1455 C C . PRO A 1 189 ? -61.228 -13.896 -4.387 1.00 65.71 ? 189 PRO A C 1 ATOM 1456 O O . PRO A 1 189 ? -60.516 -13.057 -3.841 1.00 65.94 ? 189 PRO A O 1 ATOM 1457 C CB . PRO A 1 189 ? -60.898 -13.953 -6.849 1.00 65.14 ? 189 PRO A CB 1 ATOM 1458 C CG . PRO A 1 189 ? -62.097 -14.556 -7.426 1.00 64.71 ? 189 PRO A CG 1 ATOM 1459 C CD . PRO A 1 189 ? -62.052 -15.979 -7.053 1.00 65.01 ? 189 PRO A CD 1 ATOM 1460 N N . LYS A 1 190 ? -62.485 -14.138 -4.018 1.00 65.64 ? 190 LYS A N 1 ATOM 1461 C CA . LYS A 1 190 ? -63.112 -13.361 -2.961 1.00 65.70 ? 190 LYS A CA 1 ATOM 1462 C C . LYS A 1 190 ? -62.727 -13.819 -1.569 1.00 65.20 ? 190 LYS A C 1 ATOM 1463 O O . LYS A 1 190 ? -62.969 -13.098 -0.605 1.00 65.56 ? 190 LYS A O 1 ATOM 1464 C CB . LYS A 1 190 ? -64.629 -13.367 -3.068 1.00 66.33 ? 190 LYS A CB 1 ATOM 1465 C CG . LYS A 1 190 ? -65.229 -12.240 -3.887 1.00 68.71 ? 190 LYS A CG 1 ATOM 1466 C CD . LYS A 1 190 ? -65.484 -12.717 -5.327 1.00 73.80 ? 190 LYS A CD 1 ATOM 1467 C CE . LYS A 1 190 ? -66.069 -11.612 -6.219 1.00 75.64 ? 190 LYS A CE 1 ATOM 1468 N NZ . LYS A 1 190 ? -67.451 -11.275 -5.785 1.00 77.89 ? 190 LYS A NZ 1 ATOM 1469 N N . SER A 1 191 ? -62.145 -15.008 -1.441 1.00 64.22 ? 191 SER A N 1 ATOM 1470 C CA . SER A 1 191 ? -61.708 -15.473 -0.126 1.00 63.20 ? 191 SER A CA 1 ATOM 1471 C C . SER A 1 191 ? -60.229 -15.779 -0.106 1.00 62.57 ? 191 SER A C 1 ATOM 1472 O O . SER A 1 191 ? -59.841 -16.941 -0.184 1.00 62.63 ? 191 SER A O 1 ATOM 1473 C CB . SER A 1 191 ? -62.468 -16.716 0.301 1.00 63.17 ? 191 SER A CB 1 ATOM 1474 O OG . SER A 1 191 ? -61.904 -17.219 1.496 1.00 63.37 ? 191 SER A OG 1 ATOM 1475 N N . VAL A 1 192 ? -59.408 -14.740 0.008 1.00 61.61 ? 192 VAL A N 1 ATOM 1476 C CA . VAL A 1 192 ? -57.964 -14.891 -0.101 1.00 60.85 ? 192 VAL A CA 1 ATOM 1477 C C . VAL A 1 192 ? -57.255 -14.430 1.159 1.00 60.29 ? 192 VAL A C 1 ATOM 1478 O O . VAL A 1 192 ? -57.434 -13.314 1.612 1.00 60.40 ? 192 VAL A O 1 ATOM 1479 C CB . VAL A 1 192 ? -57.393 -14.103 -1.293 1.00 60.77 ? 192 VAL A CB 1 ATOM 1480 C CG1 . VAL A 1 192 ? -55.890 -14.026 -1.188 1.00 61.14 ? 192 VAL A CG1 1 ATOM 1481 C CG2 . VAL A 1 192 ? -57.799 -14.747 -2.601 1.00 60.57 ? 192 VAL A CG2 1 ATOM 1482 N N . THR A 1 193 ? -56.427 -15.294 1.716 1.00 59.44 ? 193 THR A N 1 ATOM 1483 C CA . THR A 1 193 ? -55.746 -14.973 2.938 1.00 58.42 ? 193 THR A CA 1 ATOM 1484 C C . THR A 1 193 ? -54.268 -14.985 2.702 1.00 57.98 ? 193 THR A C 1 ATOM 1485 O O . THR A 1 193 ? -53.721 -15.994 2.310 1.00 58.47 ? 193 THR A O 1 ATOM 1486 C CB . THR A 1 193 ? -56.020 -16.010 3.992 1.00 58.16 ? 193 THR A CB 1 ATOM 1487 O OG1 . THR A 1 193 ? -57.397 -15.952 4.372 1.00 58.68 ? 193 THR A OG1 1 ATOM 1488 C CG2 . THR A 1 193 ? -55.192 -15.717 5.184 1.00 58.38 ? 193 THR A CG2 1 ATOM 1489 N N . LEU A 1 194 ? -53.612 -13.864 2.941 1.00 57.08 ? 194 LEU A N 1 ATOM 1490 C CA . LEU A 1 194 ? -52.178 -13.820 2.865 1.00 56.13 ? 194 LEU A CA 1 ATOM 1491 C C . LEU A 1 194 ? -51.637 -14.365 4.164 1.00 56.27 ? 194 LEU A C 1 ATOM 1492 O O . LEU A 1 194 ? -52.230 -14.146 5.222 1.00 56.45 ? 194 LEU A O 1 ATOM 1493 C CB . LEU A 1 194 ? -51.717 -12.387 2.710 1.00 55.67 ? 194 LEU A CB 1 ATOM 1494 C CG . LEU A 1 194 ? -52.382 -11.602 1.593 1.00 54.83 ? 194 LEU A CG 1 ATOM 1495 C CD1 . LEU A 1 194 ? -51.803 -10.217 1.519 1.00 53.92 ? 194 LEU A CD1 1 ATOM 1496 C CD2 . LEU A 1 194 ? -52.173 -12.317 0.301 1.00 54.38 ? 194 LEU A CD2 1 ATOM 1497 N N . PHE A 1 195 ? -50.525 -15.090 4.095 1.00 56.08 ? 195 PHE A N 1 ATOM 1498 C CA . PHE A 1 195 ? -49.774 -15.404 5.299 1.00 55.82 ? 195 PHE A CA 1 ATOM 1499 C C . PHE A 1 195 ? -48.309 -15.511 4.958 1.00 55.88 ? 195 PHE A C 1 ATOM 1500 O O . PHE A 1 195 ? -47.943 -15.915 3.835 1.00 56.07 ? 195 PHE A O 1 ATOM 1501 C CB . PHE A 1 195 ? -50.286 -16.672 6.006 1.00 55.72 ? 195 PHE A CB 1 ATOM 1502 C CG . PHE A 1 195 ? -50.012 -17.962 5.263 1.00 55.80 ? 195 PHE A CG 1 ATOM 1503 C CD1 . PHE A 1 195 ? -50.199 -18.053 3.884 1.00 54.96 ? 195 PHE A CD1 1 ATOM 1504 C CD2 . PHE A 1 195 ? -49.602 -19.108 5.961 1.00 55.40 ? 195 PHE A CD2 1 ATOM 1505 C CE1 . PHE A 1 195 ? -49.950 -19.263 3.206 1.00 54.86 ? 195 PHE A CE1 1 ATOM 1506 C CE2 . PHE A 1 195 ? -49.356 -20.318 5.285 1.00 54.38 ? 195 PHE A CE2 1 ATOM 1507 C CZ . PHE A 1 195 ? -49.528 -20.393 3.906 1.00 54.01 ? 195 PHE A CZ 1 ATOM 1508 N N . GLY A 1 196 ? -47.480 -15.133 5.932 1.00 55.29 ? 196 GLY A N 1 ATOM 1509 C CA . GLY A 1 196 ? -46.043 -15.118 5.763 1.00 54.56 ? 196 GLY A CA 1 ATOM 1510 C C . GLY A 1 196 ? -45.356 -15.167 7.102 1.00 54.18 ? 196 GLY A C 1 ATOM 1511 O O . GLY A 1 196 ? -45.998 -15.238 8.137 1.00 54.16 ? 196 GLY A O 1 ATOM 1512 N N . GLU A 1 197 ? -44.035 -15.120 7.077 1.00 53.95 ? 197 GLU A N 1 ATOM 1513 C CA . GLU A 1 197 ? -43.253 -15.224 8.278 1.00 53.75 ? 197 GLU A CA 1 ATOM 1514 C C . GLU A 1 197 ? -42.033 -14.325 8.147 1.00 53.66 ? 197 GLU A C 1 ATOM 1515 O O . GLU A 1 197 ? -41.579 -14.049 7.031 1.00 53.52 ? 197 GLU A O 1 ATOM 1516 C CB . GLU A 1 197 ? -42.840 -16.665 8.483 1.00 53.88 ? 197 GLU A CB 1 ATOM 1517 C CG . GLU A 1 197 ? -42.239 -16.969 9.860 1.00 55.07 ? 197 GLU A CG 1 ATOM 1518 C CD . GLU A 1 197 ? -40.703 -16.897 9.894 1.00 55.70 ? 197 GLU A CD 1 ATOM 1519 O OE1 . GLU A 1 197 ? -40.079 -16.535 8.875 1.00 53.59 ? 197 GLU A OE1 1 ATOM 1520 O OE2 . GLU A 1 197 ? -40.122 -17.217 10.954 1.00 57.08 ? 197 GLU A OE2 1 ATOM 1521 N N . SER A 1 198 ? -41.533 -13.859 9.295 1.00 53.67 ? 198 SER A N 1 ATOM 1522 C CA . SER A 1 198 ? -40.446 -12.875 9.378 1.00 53.47 ? 198 SER A CA 1 ATOM 1523 C C . SER A 1 198 ? -40.674 -11.734 8.370 1.00 53.36 ? 198 SER A C 1 ATOM 1524 O O . SER A 1 198 ? -41.692 -11.058 8.439 1.00 53.42 ? 198 SER A O 1 ATOM 1525 C CB . SER A 1 198 ? -39.093 -13.572 9.198 1.00 53.78 ? 198 SER A CB 1 ATOM 1526 O OG . SER A 1 198 ? -38.063 -12.900 9.859 1.00 53.87 ? 198 SER A OG 1 ATOM 1527 N N . ALA A 1 199 ? -39.765 -11.495 7.433 1.00 53.17 ? 199 ALA A N 1 ATOM 1528 C CA . ALA A 1 199 ? -40.036 -10.445 6.454 1.00 53.17 ? 199 ALA A CA 1 ATOM 1529 C C . ALA A 1 199 ? -41.332 -10.739 5.686 1.00 53.24 ? 199 ALA A C 1 ATOM 1530 O O . ALA A 1 199 ? -41.956 -9.857 5.093 1.00 52.40 ? 199 ALA A O 1 ATOM 1531 C CB . ALA A 1 199 ? -38.860 -10.272 5.501 1.00 53.07 ? 199 ALA A CB 1 ATOM 1532 N N . GLY A 1 200 ? -41.729 -11.999 5.707 1.00 53.65 ? 200 GLY A N 1 ATOM 1533 C CA . GLY A 1 200 ? -42.912 -12.398 5.008 1.00 54.50 ? 200 GLY A CA 1 ATOM 1534 C C . GLY A 1 200 ? -44.080 -11.765 5.688 1.00 54.98 ? 200 GLY A C 1 ATOM 1535 O O . GLY A 1 200 ? -44.916 -11.130 5.055 1.00 55.03 ? 200 GLY A O 1 ATOM 1536 N N . ALA A 1 201 ? -44.123 -11.955 6.997 1.00 55.65 ? 201 ALA A N 1 ATOM 1537 C CA . ALA A 1 201 ? -45.151 -11.373 7.847 1.00 56.06 ? 201 ALA A CA 1 ATOM 1538 C C . ALA A 1 201 ? -45.128 -9.860 7.684 1.00 56.54 ? 201 ALA A C 1 ATOM 1539 O O . ALA A 1 201 ? -46.145 -9.228 7.366 1.00 56.86 ? 201 ALA A O 1 ATOM 1540 C CB . ALA A 1 201 ? -44.907 -11.748 9.280 1.00 55.85 ? 201 ALA A CB 1 ATOM 1541 N N . ALA A 1 202 ? -43.955 -9.271 7.870 1.00 56.71 ? 202 ALA A N 1 ATOM 1542 C CA . ALA A 1 202 ? -43.833 -7.847 7.677 1.00 57.01 ? 202 ALA A CA 1 ATOM 1543 C C . ALA A 1 202 ? -44.444 -7.431 6.355 1.00 57.33 ? 202 ALA A C 1 ATOM 1544 O O . ALA A 1 202 ? -45.091 -6.407 6.275 1.00 57.70 ? 202 ALA A O 1 ATOM 1545 C CB . ALA A 1 202 ? -42.404 -7.431 7.748 1.00 56.86 ? 202 ALA A CB 1 ATOM 1546 N N . SER A 1 203 ? -44.248 -8.219 5.309 1.00 57.97 ? 203 SER A N 1 ATOM 1547 C CA . SER A 1 203 ? -44.802 -7.856 4.007 1.00 58.40 ? 203 SER A CA 1 ATOM 1548 C C . SER A 1 203 ? -46.311 -7.932 4.055 1.00 58.58 ? 203 SER A C 1 ATOM 1549 O O . SER A 1 203 ? -46.991 -7.021 3.621 1.00 58.77 ? 203 SER A O 1 ATOM 1550 C CB . SER A 1 203 ? -44.252 -8.765 2.918 1.00 58.38 ? 203 SER A CB 1 ATOM 1551 O OG . SER A 1 203 ? -42.850 -8.909 3.087 1.00 58.97 ? 203 SER A OG 1 ATOM 1552 N N . VAL A 1 204 ? -46.836 -9.017 4.603 1.00 58.90 ? 204 VAL A N 1 ATOM 1553 C CA . VAL A 1 204 ? -48.277 -9.140 4.815 1.00 59.25 ? 204 VAL A CA 1 ATOM 1554 C C . VAL A 1 204 ? -48.855 -7.888 5.476 1.00 59.08 ? 204 VAL A C 1 ATOM 1555 O O . VAL A 1 204 ? -49.878 -7.345 5.047 1.00 59.04 ? 204 VAL A O 1 ATOM 1556 C CB . VAL A 1 204 ? -48.590 -10.341 5.712 1.00 59.40 ? 204 VAL A CB 1 ATOM 1557 C CG1 . VAL A 1 204 ? -49.994 -10.231 6.286 1.00 59.44 ? 204 VAL A CG1 1 ATOM 1558 C CG2 . VAL A 1 204 ? -48.417 -11.626 4.930 1.00 60.19 ? 204 VAL A CG2 1 ATOM 1559 N N . SER A 1 205 ? -48.181 -7.428 6.521 1.00 58.59 ? 205 SER A N 1 ATOM 1560 C CA . SER A 1 205 ? -48.650 -6.272 7.237 1.00 58.16 ? 205 SER A CA 1 ATOM 1561 C C . SER A 1 205 ? -48.596 -5.025 6.353 1.00 57.93 ? 205 SER A C 1 ATOM 1562 O O . SER A 1 205 ? -49.494 -4.192 6.385 1.00 58.03 ? 205 SER A O 1 ATOM 1563 C CB . SER A 1 205 ? -47.856 -6.095 8.521 1.00 58.11 ? 205 SER A CB 1 ATOM 1564 O OG . SER A 1 205 ? -46.593 -5.522 8.263 1.00 58.39 ? 205 SER A OG 1 ATOM 1565 N N . LEU A 1 206 ? -47.572 -4.916 5.518 1.00 57.89 ? 206 LEU A N 1 ATOM 1566 C CA . LEU A 1 206 ? -47.465 -3.766 4.628 1.00 57.61 ? 206 LEU A CA 1 ATOM 1567 C C . LEU A 1 206 ? -48.613 -3.731 3.649 1.00 57.52 ? 206 LEU A C 1 ATOM 1568 O O . LEU A 1 206 ? -49.122 -2.683 3.296 1.00 57.16 ? 206 LEU A O 1 ATOM 1569 C CB . LEU A 1 206 ? -46.126 -3.764 3.915 1.00 57.29 ? 206 LEU A CB 1 ATOM 1570 C CG . LEU A 1 206 ? -45.032 -3.124 4.758 1.00 57.43 ? 206 LEU A CG 1 ATOM 1571 C CD1 . LEU A 1 206 ? -43.699 -3.489 4.224 1.00 57.55 ? 206 LEU A CD1 1 ATOM 1572 C CD2 . LEU A 1 206 ? -45.172 -1.618 4.773 1.00 58.35 ? 206 LEU A CD2 1 ATOM 1573 N N . HIS A 1 207 ? -49.049 -4.904 3.243 1.00 58.08 ? 207 HIS A N 1 ATOM 1574 C CA . HIS A 1 207 ? -50.168 -5.008 2.332 1.00 58.93 ? 207 HIS A CA 1 ATOM 1575 C C . HIS A 1 207 ? -51.462 -4.542 2.970 1.00 59.10 ? 207 HIS A C 1 ATOM 1576 O O . HIS A 1 207 ? -52.367 -4.067 2.271 1.00 59.49 ? 207 HIS A O 1 ATOM 1577 C CB . HIS A 1 207 ? -50.324 -6.443 1.867 1.00 59.08 ? 207 HIS A CB 1 ATOM 1578 C CG . HIS A 1 207 ? -49.355 -6.828 0.803 1.00 60.24 ? 207 HIS A CG 1 ATOM 1579 N ND1 . HIS A 1 207 ? -49.487 -6.407 -0.502 1.00 60.59 ? 207 HIS A ND1 1 ATOM 1580 C CD2 . HIS A 1 207 ? -48.231 -7.581 0.850 1.00 60.90 ? 207 HIS A CD2 1 ATOM 1581 C CE1 . HIS A 1 207 ? -48.492 -6.897 -1.218 1.00 60.78 ? 207 HIS A CE1 1 ATOM 1582 N NE2 . HIS A 1 207 ? -47.714 -7.611 -0.422 1.00 60.20 ? 207 HIS A NE2 1 ATOM 1583 N N . LEU A 1 208 ? -51.566 -4.699 4.290 1.00 58.92 ? 208 LEU A N 1 ATOM 1584 C CA . LEU A 1 208 ? -52.728 -4.193 4.998 1.00 58.45 ? 208 LEU A CA 1 ATOM 1585 C C . LEU A 1 208 ? -52.745 -2.694 4.888 1.00 58.72 ? 208 LEU A C 1 ATOM 1586 O O . LEU A 1 208 ? -53.820 -2.097 4.891 1.00 58.74 ? 208 LEU A O 1 ATOM 1587 C CB . LEU A 1 208 ? -52.724 -4.593 6.461 1.00 58.02 ? 208 LEU A CB 1 ATOM 1588 C CG . LEU A 1 208 ? -52.985 -6.061 6.715 1.00 56.66 ? 208 LEU A CG 1 ATOM 1589 C CD1 . LEU A 1 208 ? -52.815 -6.349 8.162 1.00 53.91 ? 208 LEU A CD1 1 ATOM 1590 C CD2 . LEU A 1 208 ? -54.360 -6.422 6.254 1.00 55.52 ? 208 LEU A CD2 1 ATOM 1591 N N . LEU A 1 209 ? -51.564 -2.090 4.771 1.00 58.86 ? 209 LEU A N 1 ATOM 1592 C CA . LEU A 1 209 ? -51.482 -0.643 4.671 1.00 59.42 ? 209 LEU A CA 1 ATOM 1593 C C . LEU A 1 209 ? -51.529 -0.145 3.248 1.00 60.02 ? 209 LEU A C 1 ATOM 1594 O O . LEU A 1 209 ? -51.983 0.959 2.987 1.00 60.31 ? 209 LEU A O 1 ATOM 1595 C CB . LEU A 1 209 ? -50.252 -0.099 5.371 1.00 59.25 ? 209 LEU A CB 1 ATOM 1596 C CG . LEU A 1 209 ? -50.181 -0.565 6.819 1.00 59.42 ? 209 LEU A CG 1 ATOM 1597 C CD1 . LEU A 1 209 ? -49.043 0.110 7.547 1.00 59.22 ? 209 LEU A CD1 1 ATOM 1598 C CD2 . LEU A 1 209 ? -51.490 -0.277 7.496 1.00 60.41 ? 209 LEU A CD2 1 ATOM 1599 N N . SER A 1 210 ? -51.070 -0.942 2.300 1.00 60.92 ? 210 SER A N 1 ATOM 1600 C CA . SER A 1 210 ? -51.060 -0.428 0.940 1.00 61.38 ? 210 SER A CA 1 ATOM 1601 C C . SER A 1 210 ? -52.461 -0.394 0.410 1.00 61.41 ? 210 SER A C 1 ATOM 1602 O O . SER A 1 210 ? -53.194 -1.374 0.557 1.00 61.16 ? 210 SER A O 1 ATOM 1603 C CB . SER A 1 210 ? -50.182 -1.240 0.009 1.00 61.38 ? 210 SER A CB 1 ATOM 1604 O OG . SER A 1 210 ? -50.262 -0.684 -1.295 1.00 62.43 ? 210 SER A OG 1 ATOM 1605 N N . PRO A 1 211 ? -52.851 0.750 -0.179 1.00 61.82 ? 211 PRO A N 1 ATOM 1606 C CA . PRO A 1 211 ? -54.168 0.843 -0.811 1.00 62.09 ? 211 PRO A CA 1 ATOM 1607 C C . PRO A 1 211 ? -54.139 0.005 -2.079 1.00 62.35 ? 211 PRO A C 1 ATOM 1608 O O . PRO A 1 211 ? -55.111 -0.666 -2.422 1.00 62.11 ? 211 PRO A O 1 ATOM 1609 C CB . PRO A 1 211 ? -54.333 2.342 -1.096 1.00 61.57 ? 211 PRO A CB 1 ATOM 1610 C CG . PRO A 1 211 ? -52.958 2.869 -1.138 1.00 61.83 ? 211 PRO A CG 1 ATOM 1611 C CD . PRO A 1 211 ? -52.107 2.019 -0.243 1.00 61.79 ? 211 PRO A CD 1 ATOM 1612 N N . GLY A 1 212 ? -52.997 0.000 -2.744 1.00 62.82 ? 212 GLY A N 1 ATOM 1613 C CA . GLY A 1 212 ? -52.849 -0.826 -3.922 1.00 63.44 ? 212 GLY A CA 1 ATOM 1614 C C . GLY A 1 212 ? -53.256 -2.274 -3.725 1.00 63.57 ? 212 GLY A C 1 ATOM 1615 O O . GLY A 1 212 ? -53.590 -2.943 -4.692 1.00 63.78 ? 212 GLY A O 1 ATOM 1616 N N . SER A 1 213 ? -53.210 -2.757 -2.481 1.00 63.68 ? 213 SER A N 1 ATOM 1617 C CA . SER A 1 213 ? -53.510 -4.160 -2.163 1.00 63.64 ? 213 SER A CA 1 ATOM 1618 C C . SER A 1 213 ? -54.879 -4.356 -1.533 1.00 63.71 ? 213 SER A C 1 ATOM 1619 O O . SER A 1 213 ? -55.403 -5.453 -1.512 1.00 63.60 ? 213 SER A O 1 ATOM 1620 C CB . SER A 1 213 ? -52.463 -4.738 -1.220 1.00 63.50 ? 213 SER A CB 1 ATOM 1621 O OG . SER A 1 213 ? -51.174 -4.582 -1.759 1.00 64.12 ? 213 SER A OG 1 ATOM 1622 N N A HIS A 1 214 ? -55.445 -3.290 -0.986 0.50 63.84 ? 214 HIS A N 1 ATOM 1623 N N B HIS A 1 214 ? -55.464 -3.266 -1.049 0.50 63.99 ? 214 HIS A N 1 ATOM 1624 C CA A HIS A 1 214 ? -56.717 -3.401 -0.289 0.50 63.83 ? 214 HIS A CA 1 ATOM 1625 C CA B HIS A 1 214 ? -56.720 -3.307 -0.299 0.50 64.12 ? 214 HIS A CA 1 ATOM 1626 C C A HIS A 1 214 ? -57.546 -4.534 -0.870 0.50 63.92 ? 214 HIS A C 1 ATOM 1627 C C B HIS A 1 214 ? -57.811 -4.202 -0.884 0.50 64.10 ? 214 HIS A C 1 ATOM 1628 O O A HIS A 1 214 ? -57.979 -5.435 -0.153 0.50 64.13 ? 214 HIS A O 1 ATOM 1629 O O B HIS A 1 214 ? -58.712 -4.609 -0.158 0.50 64.43 ? 214 HIS A O 1 ATOM 1630 C CB A HIS A 1 214 ? -57.508 -2.095 -0.383 0.50 63.89 ? 214 HIS A CB 1 ATOM 1631 C CB B HIS A 1 214 ? -57.293 -1.896 -0.097 0.50 64.31 ? 214 HIS A CB 1 ATOM 1632 C CG A HIS A 1 214 ? -58.748 -2.075 0.456 0.50 63.26 ? 214 HIS A CG 1 ATOM 1633 C CG B HIS A 1 214 ? -56.661 -1.134 1.028 0.50 64.28 ? 214 HIS A CG 1 ATOM 1634 N ND1 A HIS A 1 214 ? -58.987 -1.106 1.405 0.50 62.97 ? 214 HIS A ND1 1 ATOM 1635 N ND1 B HIS A 1 214 ? -55.693 -1.678 1.849 0.50 64.19 ? 214 HIS A ND1 1 ATOM 1636 C CD2 A HIS A 1 214 ? -59.809 -2.914 0.500 0.50 62.31 ? 214 HIS A CD2 1 ATOM 1637 C CD2 B HIS A 1 214 ? -56.880 0.124 1.482 0.50 63.72 ? 214 HIS A CD2 1 ATOM 1638 C CE1 A HIS A 1 214 ? -60.148 -1.342 1.988 0.50 62.44 ? 214 HIS A CE1 1 ATOM 1639 C CE1 B HIS A 1 214 ? -55.334 -0.780 2.751 0.50 64.57 ? 214 HIS A CE1 1 ATOM 1640 N NE2 A HIS A 1 214 ? -60.668 -2.433 1.455 0.50 61.95 ? 214 HIS A NE2 1 ATOM 1641 N NE2 B HIS A 1 214 ? -56.041 0.321 2.553 0.50 64.13 ? 214 HIS A NE2 1 ATOM 1642 N N . SER A 1 215 ? -57.763 -4.500 -2.176 1.00 63.80 ? 215 SER A N 1 ATOM 1643 C CA . SER A 1 215 ? -58.789 -5.351 -2.755 1.00 63.77 ? 215 SER A CA 1 ATOM 1644 C C . SER A 1 215 ? -58.275 -6.640 -3.362 1.00 63.61 ? 215 SER A C 1 ATOM 1645 O O . SER A 1 215 ? -59.004 -7.319 -4.087 1.00 63.31 ? 215 SER A O 1 ATOM 1646 C CB . SER A 1 215 ? -59.474 -4.611 -3.857 1.00 63.84 ? 215 SER A CB 1 ATOM 1647 O OG . SER A 1 215 ? -58.635 -4.725 -4.978 1.00 64.76 ? 215 SER A OG 1 ATOM 1648 N N . LEU A 1 216 ? -57.020 -6.967 -3.087 1.00 63.56 ? 216 LEU A N 1 ATOM 1649 C CA . LEU A 1 216 ? -56.393 -8.128 -3.696 1.00 63.00 ? 216 LEU A CA 1 ATOM 1650 C C . LEU A 1 216 ? -56.412 -9.319 -2.757 1.00 62.89 ? 216 LEU A C 1 ATOM 1651 O O . LEU A 1 216 ? -55.994 -10.404 -3.133 1.00 63.35 ? 216 LEU A O 1 ATOM 1652 C CB . LEU A 1 216 ? -54.973 -7.795 -4.119 1.00 62.74 ? 216 LEU A CB 1 ATOM 1653 C CG . LEU A 1 216 ? -54.948 -6.528 -4.955 1.00 62.53 ? 216 LEU A CG 1 ATOM 1654 C CD1 . LEU A 1 216 ? -53.561 -5.995 -5.117 1.00 62.49 ? 216 LEU A CD1 1 ATOM 1655 C CD2 . LEU A 1 216 ? -55.540 -6.808 -6.314 1.00 63.47 ? 216 LEU A CD2 1 ATOM 1656 N N . PHE A 1 217 ? -56.921 -9.133 -1.548 1.00 62.33 ? 217 PHE A N 1 ATOM 1657 C CA . PHE A 1 217 ? -57.029 -10.244 -0.625 1.00 62.06 ? 217 PHE A CA 1 ATOM 1658 C C . PHE A 1 217 ? -58.087 -9.978 0.453 1.00 61.76 ? 217 PHE A C 1 ATOM 1659 O O . PHE A 1 217 ? -58.657 -8.904 0.504 1.00 62.29 ? 217 PHE A O 1 ATOM 1660 C CB . PHE A 1 217 ? -55.667 -10.498 0.002 1.00 62.30 ? 217 PHE A CB 1 ATOM 1661 C CG . PHE A 1 217 ? -55.230 -9.419 0.955 1.00 62.58 ? 217 PHE A CG 1 ATOM 1662 C CD1 . PHE A 1 217 ? -54.807 -8.195 0.475 1.00 62.03 ? 217 PHE A CD1 1 ATOM 1663 C CD2 . PHE A 1 217 ? -55.264 -9.632 2.326 1.00 61.14 ? 217 PHE A CD2 1 ATOM 1664 C CE1 . PHE A 1 217 ? -54.423 -7.210 1.346 1.00 62.52 ? 217 PHE A CE1 1 ATOM 1665 C CE2 . PHE A 1 217 ? -54.872 -8.668 3.187 1.00 61.41 ? 217 PHE A CE2 1 ATOM 1666 C CZ . PHE A 1 217 ? -54.453 -7.449 2.712 1.00 62.22 ? 217 PHE A CZ 1 ATOM 1667 N N . THR A 1 218 ? -58.310 -10.940 1.337 1.00 61.10 ? 218 THR A N 1 ATOM 1668 C CA . THR A 1 218 ? -59.406 -10.872 2.296 1.00 60.48 ? 218 THR A CA 1 ATOM 1669 C C . THR A 1 218 ? -58.957 -10.771 3.757 1.00 60.10 ? 218 THR A C 1 ATOM 1670 O O . THR A 1 218 ? -59.360 -9.855 4.479 1.00 60.20 ? 218 THR A O 1 ATOM 1671 C CB . THR A 1 218 ? -60.281 -12.112 2.162 1.00 60.61 ? 218 THR A CB 1 ATOM 1672 O OG1 . THR A 1 218 ? -60.775 -12.200 0.820 1.00 60.64 ? 218 THR A OG1 1 ATOM 1673 C CG2 . THR A 1 218 ? -61.429 -12.072 3.163 1.00 59.76 ? 218 THR A CG2 1 ATOM 1674 N N . ARG A 1 219 ? -58.134 -11.727 4.185 1.00 59.42 ? 219 ARG A N 1 ATOM 1675 C CA . ARG A 1 219 ? -57.612 -11.772 5.552 1.00 58.56 ? 219 ARG A CA 1 ATOM 1676 C C . ARG A 1 219 ? -56.090 -11.834 5.596 1.00 58.03 ? 219 ARG A C 1 ATOM 1677 O O . ARG A 1 219 ? -55.440 -11.873 4.568 1.00 58.49 ? 219 ARG A O 1 ATOM 1678 C CB . ARG A 1 219 ? -58.182 -12.971 6.289 1.00 58.59 ? 219 ARG A CB 1 ATOM 1679 C CG . ARG A 1 219 ? -59.529 -12.707 6.894 1.00 58.13 ? 219 ARG A CG 1 ATOM 1680 C CD . ARG A 1 219 ? -60.042 -13.935 7.594 1.00 58.34 ? 219 ARG A CD 1 ATOM 1681 N NE . ARG A 1 219 ? -60.962 -14.710 6.776 1.00 58.93 ? 219 ARG A NE 1 ATOM 1682 C CZ . ARG A 1 219 ? -62.125 -14.248 6.338 1.00 59.20 ? 219 ARG A CZ 1 ATOM 1683 N NH1 . ARG A 1 219 ? -62.917 -15.019 5.621 1.00 60.32 ? 219 ARG A NH1 1 ATOM 1684 N NH2 . ARG A 1 219 ? -62.502 -13.016 6.616 1.00 59.27 ? 219 ARG A NH2 1 ATOM 1685 N N . ALA A 1 220 ? -55.524 -11.853 6.795 1.00 57.20 ? 220 ALA A N 1 ATOM 1686 C CA . ALA A 1 220 ? -54.070 -11.814 6.958 1.00 56.19 ? 220 ALA A CA 1 ATOM 1687 C C . ALA A 1 220 ? -53.587 -12.588 8.188 1.00 55.66 ? 220 ALA A C 1 ATOM 1688 O O . ALA A 1 220 ? -54.215 -12.556 9.247 1.00 55.17 ? 220 ALA A O 1 ATOM 1689 C CB . ALA A 1 220 ? -53.585 -10.376 7.023 1.00 55.88 ? 220 ALA A CB 1 ATOM 1690 N N . ILE A 1 221 ? -52.469 -13.290 8.020 1.00 55.31 ? 221 ILE A N 1 ATOM 1691 C CA . ILE A 1 221 ? -51.800 -13.993 9.113 1.00 55.23 ? 221 ILE A CA 1 ATOM 1692 C C . ILE A 1 221 ? -50.361 -13.534 9.140 1.00 55.33 ? 221 ILE A C 1 ATOM 1693 O O . ILE A 1 221 ? -49.753 -13.367 8.082 1.00 55.61 ? 221 ILE A O 1 ATOM 1694 C CB . ILE A 1 221 ? -51.813 -15.505 8.912 1.00 55.19 ? 221 ILE A CB 1 ATOM 1695 C CG1 . ILE A 1 221 ? -53.255 -15.994 8.785 1.00 55.51 ? 221 ILE A CG1 1 ATOM 1696 C CG2 . ILE A 1 221 ? -51.118 -16.175 10.078 1.00 53.86 ? 221 ILE A CG2 1 ATOM 1697 C CD1 . ILE A 1 221 ? -53.364 -17.314 8.190 1.00 55.54 ? 221 ILE A CD1 1 ATOM 1698 N N . LEU A 1 222 ? -49.830 -13.325 10.344 1.00 55.14 ? 222 LEU A N 1 ATOM 1699 C CA . LEU A 1 222 ? -48.523 -12.702 10.530 1.00 54.98 ? 222 LEU A CA 1 ATOM 1700 C C . LEU A 1 222 ? -47.741 -13.525 11.521 1.00 55.32 ? 222 LEU A C 1 ATOM 1701 O O . LEU A 1 222 ? -48.006 -13.473 12.731 1.00 55.67 ? 222 LEU A O 1 ATOM 1702 C CB . LEU A 1 222 ? -48.659 -11.265 11.051 1.00 54.44 ? 222 LEU A CB 1 ATOM 1703 C CG . LEU A 1 222 ? -49.074 -10.178 10.051 1.00 54.40 ? 222 LEU A CG 1 ATOM 1704 C CD1 . LEU A 1 222 ? -50.428 -10.444 9.406 1.00 53.25 ? 222 LEU A CD1 1 ATOM 1705 C CD2 . LEU A 1 222 ? -49.070 -8.794 10.671 1.00 53.72 ? 222 LEU A CD2 1 ATOM 1706 N N . GLN A 1 223 ? -46.785 -14.298 11.016 1.00 55.39 ? 223 GLN A N 1 ATOM 1707 C CA . GLN A 1 223 ? -45.990 -15.151 11.883 1.00 55.47 ? 223 GLN A CA 1 ATOM 1708 C C . GLN A 1 223 ? -44.610 -14.544 12.110 1.00 55.52 ? 223 GLN A C 1 ATOM 1709 O O . GLN A 1 223 ? -43.871 -14.287 11.156 1.00 55.24 ? 223 GLN A O 1 ATOM 1710 C CB . GLN A 1 223 ? -45.874 -16.536 11.272 1.00 55.64 ? 223 GLN A CB 1 ATOM 1711 C CG . GLN A 1 223 ? -47.192 -17.074 10.787 1.00 56.03 ? 223 GLN A CG 1 ATOM 1712 C CD . GLN A 1 223 ? -47.084 -18.454 10.196 1.00 57.00 ? 223 GLN A CD 1 ATOM 1713 O OE1 . GLN A 1 223 ? -47.977 -18.912 9.493 1.00 57.18 ? 223 GLN A OE1 1 ATOM 1714 N NE2 . GLN A 1 223 ? -45.986 -19.133 10.482 1.00 58.64 ? 223 GLN A NE2 1 ATOM 1715 N N . SER A 1 224 ? -44.279 -14.318 13.385 1.00 55.55 ? 224 SER A N 1 ATOM 1716 C CA . SER A 1 224 ? -43.032 -13.649 13.788 1.00 55.08 ? 224 SER A CA 1 ATOM 1717 C C . SER A 1 224 ? -42.641 -12.509 12.838 1.00 55.25 ? 224 SER A C 1 ATOM 1718 O O . SER A 1 224 ? -41.646 -12.582 12.101 1.00 55.30 ? 224 SER A O 1 ATOM 1719 C CB . SER A 1 224 ? -41.897 -14.662 13.945 1.00 54.67 ? 224 SER A CB 1 ATOM 1720 O OG . SER A 1 224 ? -42.327 -15.738 14.756 1.00 53.43 ? 224 SER A OG 1 ATOM 1721 N N . GLY A 1 225 ? -43.426 -11.442 12.855 1.00 54.99 ? 225 GLY A N 1 ATOM 1722 C CA . GLY A 1 225 ? -43.044 -10.274 12.102 1.00 55.10 ? 225 GLY A CA 1 ATOM 1723 C C . GLY A 1 225 ? -44.166 -9.313 11.826 1.00 55.18 ? 225 GLY A C 1 ATOM 1724 O O . GLY A 1 225 ? -45.326 -9.716 11.768 1.00 55.51 ? 225 GLY A O 1 ATOM 1725 N N . SER A 1 226 ? -43.795 -8.050 11.614 1.00 55.07 ? 226 SER A N 1 ATOM 1726 C CA . SER A 1 226 ? -44.720 -6.938 11.459 1.00 55.02 ? 226 SER A CA 1 ATOM 1727 C C . SER A 1 226 ? -43.933 -5.716 11.030 1.00 55.10 ? 226 SER A C 1 ATOM 1728 O O . SER A 1 226 ? -42.786 -5.538 11.441 1.00 54.99 ? 226 SER A O 1 ATOM 1729 C CB . SER A 1 226 ? -45.395 -6.643 12.800 1.00 55.11 ? 226 SER A CB 1 ATOM 1730 O OG . SER A 1 226 ? -44.548 -6.983 13.893 1.00 55.57 ? 226 SER A OG 1 ATOM 1731 N N . PHE A 1 227 ? -44.536 -4.846 10.232 1.00 55.16 ? 227 PHE A N 1 ATOM 1732 C CA . PHE A 1 227 ? -43.778 -3.710 9.706 1.00 55.47 ? 227 PHE A CA 1 ATOM 1733 C C . PHE A 1 227 ? -43.134 -2.840 10.784 1.00 54.93 ? 227 PHE A C 1 ATOM 1734 O O . PHE A 1 227 ? -42.034 -2.332 10.634 1.00 54.70 ? 227 PHE A O 1 ATOM 1735 C CB . PHE A 1 227 ? -44.659 -2.869 8.816 1.00 55.68 ? 227 PHE A CB 1 ATOM 1736 C CG . PHE A 1 227 ? -45.586 -1.975 9.563 1.00 57.31 ? 227 PHE A CG 1 ATOM 1737 C CD1 . PHE A 1 227 ? -46.937 -2.296 9.691 1.00 58.30 ? 227 PHE A CD1 1 ATOM 1738 C CD2 . PHE A 1 227 ? -45.118 -0.794 10.122 1.00 58.69 ? 227 PHE A CD2 1 ATOM 1739 C CE1 . PHE A 1 227 ? -47.813 -1.452 10.338 1.00 57.85 ? 227 PHE A CE1 1 ATOM 1740 C CE2 . PHE A 1 227 ? -45.984 0.063 10.786 1.00 59.42 ? 227 PHE A CE2 1 ATOM 1741 C CZ . PHE A 1 227 ? -47.339 -0.272 10.891 1.00 59.34 ? 227 PHE A CZ 1 ATOM 1742 N N . ASN A 1 228 ? -43.833 -2.689 11.887 1.00 54.96 ? 228 ASN A N 1 ATOM 1743 C CA . ASN A 1 228 ? -43.345 -1.899 12.988 1.00 54.83 ? 228 ASN A CA 1 ATOM 1744 C C . ASN A 1 228 ? -42.148 -2.502 13.716 1.00 54.91 ? 228 ASN A C 1 ATOM 1745 O O . ASN A 1 228 ? -41.717 -1.943 14.721 1.00 54.80 ? 228 ASN A O 1 ATOM 1746 C CB . ASN A 1 228 ? -44.471 -1.649 13.980 1.00 54.67 ? 228 ASN A CB 1 ATOM 1747 C CG . ASN A 1 228 ? -44.927 -2.908 14.667 1.00 54.96 ? 228 ASN A CG 1 ATOM 1748 O OD1 . ASN A 1 228 ? -44.976 -3.973 14.064 1.00 54.59 ? 228 ASN A OD1 1 ATOM 1749 N ND2 . ASN A 1 228 ? -45.260 -2.794 15.949 1.00 55.99 ? 228 ASN A ND2 1 ATOM 1750 N N . ALA A 1 229 ? -41.605 -3.627 13.222 1.00 54.97 ? 229 ALA A N 1 ATOM 1751 C CA . ALA A 1 229 ? -40.369 -4.214 13.800 1.00 54.60 ? 229 ALA A CA 1 ATOM 1752 C C . ALA A 1 229 ? -39.163 -3.372 13.442 1.00 54.32 ? 229 ALA A C 1 ATOM 1753 O O . ALA A 1 229 ? -39.126 -2.770 12.388 1.00 54.06 ? 229 ALA A O 1 ATOM 1754 C CB . ALA A 1 229 ? -40.151 -5.620 13.337 1.00 54.46 ? 229 ALA A CB 1 ATOM 1755 N N . PRO A 1 230 ? -38.167 -3.325 14.328 1.00 54.45 ? 230 PRO A N 1 ATOM 1756 C CA . PRO A 1 230 ? -37.119 -2.349 14.114 1.00 54.47 ? 230 PRO A CA 1 ATOM 1757 C C . PRO A 1 230 ? -36.438 -2.572 12.791 1.00 54.67 ? 230 PRO A C 1 ATOM 1758 O O . PRO A 1 230 ? -35.994 -1.634 12.167 1.00 54.61 ? 230 PRO A O 1 ATOM 1759 C CB . PRO A 1 230 ? -36.150 -2.591 15.277 1.00 54.31 ? 230 PRO A CB 1 ATOM 1760 C CG . PRO A 1 230 ? -36.530 -3.910 15.862 1.00 54.30 ? 230 PRO A CG 1 ATOM 1761 C CD . PRO A 1 230 ? -37.969 -4.112 15.558 1.00 54.62 ? 230 PRO A CD 1 ATOM 1762 N N . TRP A 1 231 ? -36.382 -3.814 12.347 1.00 55.46 ? 231 TRP A N 1 ATOM 1763 C CA . TRP A 1 231 ? -35.630 -4.158 11.144 1.00 55.79 ? 231 TRP A CA 1 ATOM 1764 C C . TRP A 1 231 ? -36.402 -4.017 9.826 1.00 56.68 ? 231 TRP A C 1 ATOM 1765 O O . TRP A 1 231 ? -35.853 -4.277 8.777 1.00 56.89 ? 231 TRP A O 1 ATOM 1766 C CB . TRP A 1 231 ? -35.128 -5.591 11.265 1.00 55.05 ? 231 TRP A CB 1 ATOM 1767 C CG . TRP A 1 231 ? -36.189 -6.556 11.678 1.00 53.14 ? 231 TRP A CG 1 ATOM 1768 C CD1 . TRP A 1 231 ? -36.377 -7.073 12.920 1.00 52.44 ? 231 TRP A CD1 1 ATOM 1769 C CD2 . TRP A 1 231 ? -37.203 -7.132 10.849 1.00 52.15 ? 231 TRP A CD2 1 ATOM 1770 N NE1 . TRP A 1 231 ? -37.438 -7.940 12.920 1.00 51.95 ? 231 TRP A NE1 1 ATOM 1771 C CE2 . TRP A 1 231 ? -37.963 -7.994 11.657 1.00 51.02 ? 231 TRP A CE2 1 ATOM 1772 C CE3 . TRP A 1 231 ? -37.539 -7.009 9.500 1.00 52.33 ? 231 TRP A CE3 1 ATOM 1773 C CZ2 . TRP A 1 231 ? -39.032 -8.726 11.166 1.00 50.00 ? 231 TRP A CZ2 1 ATOM 1774 C CZ3 . TRP A 1 231 ? -38.612 -7.738 9.013 1.00 51.67 ? 231 TRP A CZ3 1 ATOM 1775 C CH2 . TRP A 1 231 ? -39.345 -8.581 9.844 1.00 51.10 ? 231 TRP A CH2 1 ATOM 1776 N N . ALA A 1 232 ? -37.658 -3.600 9.871 1.00 57.91 ? 232 ALA A N 1 ATOM 1777 C CA . ALA A 1 232 ? -38.549 -3.806 8.750 1.00 59.60 ? 232 ALA A CA 1 ATOM 1778 C C . ALA A 1 232 ? -38.679 -2.649 7.736 1.00 61.34 ? 232 ALA A C 1 ATOM 1779 O O . ALA A 1 232 ? -38.923 -2.868 6.537 1.00 61.39 ? 232 ALA A O 1 ATOM 1780 C CB . ALA A 1 232 ? -39.903 -4.227 9.266 1.00 59.34 ? 232 ALA A CB 1 ATOM 1781 N N . VAL A 1 233 ? -38.533 -1.418 8.198 1.00 63.31 ? 233 VAL A N 1 ATOM 1782 C CA . VAL A 1 233 ? -38.661 -0.305 7.274 1.00 65.37 ? 233 VAL A CA 1 ATOM 1783 C C . VAL A 1 233 ? -37.470 0.609 7.404 1.00 66.94 ? 233 VAL A C 1 ATOM 1784 O O . VAL A 1 233 ? -36.908 0.736 8.480 1.00 66.89 ? 233 VAL A O 1 ATOM 1785 C CB . VAL A 1 233 ? -39.984 0.454 7.470 1.00 65.17 ? 233 VAL A CB 1 ATOM 1786 C CG1 . VAL A 1 233 ? -40.149 1.505 6.398 1.00 65.32 ? 233 VAL A CG1 1 ATOM 1787 C CG2 . VAL A 1 233 ? -41.137 -0.516 7.404 1.00 64.79 ? 233 VAL A CG2 1 ATOM 1788 N N . THR A 1 234 ? -37.076 1.218 6.292 1.00 69.55 ? 234 THR A N 1 ATOM 1789 C CA . THR A 1 234 ? -35.893 2.052 6.249 1.00 72.15 ? 234 THR A CA 1 ATOM 1790 C C . THR A 1 234 ? -36.278 3.478 5.998 1.00 73.91 ? 234 THR A C 1 ATOM 1791 O O . THR A 1 234 ? -37.186 3.751 5.206 1.00 73.98 ? 234 THR A O 1 ATOM 1792 C CB . THR A 1 234 ? -35.028 1.649 5.112 1.00 72.16 ? 234 THR A CB 1 ATOM 1793 O OG1 . THR A 1 234 ? -34.853 0.225 5.152 1.00 73.40 ? 234 THR A OG1 1 ATOM 1794 C CG2 . THR A 1 234 ? -33.699 2.350 5.202 1.00 72.56 ? 234 THR A CG2 1 ATOM 1795 N N . SER A 1 235 ? -35.596 4.392 6.679 1.00 76.24 ? 235 SER A N 1 ATOM 1796 C CA . SER A 1 235 ? -35.947 5.791 6.566 1.00 78.67 ? 235 SER A CA 1 ATOM 1797 C C . SER A 1 235 ? -35.481 6.213 5.205 1.00 80.48 ? 235 SER A C 1 ATOM 1798 O O . SER A 1 235 ? -34.517 5.668 4.677 1.00 80.84 ? 235 SER A O 1 ATOM 1799 C CB . SER A 1 235 ? -35.295 6.642 7.655 1.00 78.44 ? 235 SER A CB 1 ATOM 1800 O OG . SER A 1 235 ? -33.896 6.728 7.475 1.00 78.41 ? 235 SER A OG 1 ATOM 1801 N N . LEU A 1 236 ? -36.191 7.169 4.629 1.00 82.76 ? 236 LEU A N 1 ATOM 1802 C CA . LEU A 1 236 ? -35.863 7.700 3.319 1.00 84.98 ? 236 LEU A CA 1 ATOM 1803 C C . LEU A 1 236 ? -34.461 8.266 3.253 1.00 86.35 ? 236 LEU A C 1 ATOM 1804 O O . LEU A 1 236 ? -33.955 8.543 2.172 1.00 86.47 ? 236 LEU A O 1 ATOM 1805 C CB . LEU A 1 236 ? -36.815 8.833 2.998 1.00 85.24 ? 236 LEU A CB 1 ATOM 1806 C CG . LEU A 1 236 ? -37.007 9.089 1.521 1.00 85.99 ? 236 LEU A CG 1 ATOM 1807 C CD1 . LEU A 1 236 ? -37.954 8.013 0.995 1.00 86.21 ? 236 LEU A CD1 1 ATOM 1808 C CD2 . LEU A 1 236 ? -37.588 10.495 1.338 1.00 86.63 ? 236 LEU A CD2 1 ATOM 1809 N N . TYR A 1 237 ? -33.854 8.463 4.417 1.00 88.22 ? 237 TYR A N 1 ATOM 1810 C CA . TYR A 1 237 ? -32.505 8.985 4.494 1.00 90.18 ? 237 TYR A CA 1 ATOM 1811 C C . TYR A 1 237 ? -31.495 7.857 4.261 1.00 90.37 ? 237 TYR A C 1 ATOM 1812 O O . TYR A 1 237 ? -30.700 7.931 3.321 1.00 90.65 ? 237 TYR A O 1 ATOM 1813 C CB . TYR A 1 237 ? -32.291 9.717 5.833 1.00 91.05 ? 237 TYR A CB 1 ATOM 1814 C CG . TYR A 1 237 ? -30.856 10.162 6.109 1.00 94.81 ? 237 TYR A CG 1 ATOM 1815 C CD1 . TYR A 1 237 ? -30.287 10.022 7.396 1.00 97.19 ? 237 TYR A CD1 1 ATOM 1816 C CD2 . TYR A 1 237 ? -30.058 10.710 5.082 1.00 97.69 ? 237 TYR A CD2 1 ATOM 1817 C CE1 . TYR A 1 237 ? -28.957 10.424 7.658 1.00 99.26 ? 237 TYR A CE1 1 ATOM 1818 C CE2 . TYR A 1 237 ? -28.723 11.115 5.325 1.00 99.44 ? 237 TYR A CE2 1 ATOM 1819 C CZ . TYR A 1 237 ? -28.177 10.972 6.614 1.00 100.32 ? 237 TYR A CZ 1 ATOM 1820 O OH . TYR A 1 237 ? -26.867 11.372 6.844 1.00 100.44 ? 237 TYR A OH 1 ATOM 1821 N N . GLU A 1 238 ? -31.534 6.812 5.089 1.00 90.63 ? 238 GLU A N 1 ATOM 1822 C CA . GLU A 1 238 ? -30.615 5.686 4.908 1.00 91.10 ? 238 GLU A CA 1 ATOM 1823 C C . GLU A 1 238 ? -30.809 5.056 3.541 1.00 91.13 ? 238 GLU A C 1 ATOM 1824 O O . GLU A 1 238 ? -29.860 4.652 2.881 1.00 90.93 ? 238 GLU A O 1 ATOM 1825 C CB . GLU A 1 238 ? -30.842 4.626 5.965 1.00 91.12 ? 238 GLU A CB 1 ATOM 1826 C CG . GLU A 1 238 ? -30.831 5.151 7.360 1.00 92.67 ? 238 GLU A CG 1 ATOM 1827 C CD . GLU A 1 238 ? -31.747 4.360 8.267 1.00 94.96 ? 238 GLU A CD 1 ATOM 1828 O OE1 . GLU A 1 238 ? -32.913 4.130 7.890 1.00 96.25 ? 238 GLU A OE1 1 ATOM 1829 O OE2 . GLU A 1 238 ? -31.313 3.972 9.362 1.00 95.58 ? 238 GLU A OE2 1 ATOM 1830 N N . ALA A 1 239 ? -32.058 4.962 3.123 1.00 91.43 ? 239 ALA A N 1 ATOM 1831 C CA . ALA A 1 239 ? -32.362 4.435 1.819 1.00 91.73 ? 239 ALA A CA 1 ATOM 1832 C C . ALA A 1 239 ? -31.443 5.082 0.804 1.00 91.94 ? 239 ALA A C 1 ATOM 1833 O O . ALA A 1 239 ? -30.845 4.398 -0.017 1.00 92.24 ? 239 ALA A O 1 ATOM 1834 C CB . ALA A 1 239 ? -33.798 4.710 1.477 1.00 91.83 ? 239 ALA A CB 1 ATOM 1835 N N . ARG A 1 240 ? -31.330 6.402 0.863 1.00 92.01 ? 240 ARG A N 1 ATOM 1836 C CA . ARG A 1 240 ? -30.414 7.106 -0.024 1.00 92.15 ? 240 ARG A CA 1 ATOM 1837 C C . ARG A 1 240 ? -28.951 6.848 0.324 1.00 91.83 ? 240 ARG A C 1 ATOM 1838 O O . ARG A 1 240 ? -28.198 6.412 -0.537 1.00 91.89 ? 240 ARG A O 1 ATOM 1839 C CB . ARG A 1 240 ? -30.682 8.607 -0.044 1.00 92.45 ? 240 ARG A CB 1 ATOM 1840 C CG . ARG A 1 240 ? -31.822 9.047 -0.977 1.00 93.59 ? 240 ARG A CG 1 ATOM 1841 C CD . ARG A 1 240 ? -31.476 10.319 -1.788 1.00 94.47 ? 240 ARG A CD 1 ATOM 1842 N NE . ARG A 1 240 ? -30.547 11.192 -1.076 1.00 94.38 ? 240 ARG A NE 1 ATOM 1843 C CZ . ARG A 1 240 ? -29.648 11.966 -1.668 1.00 94.25 ? 240 ARG A CZ 1 ATOM 1844 N NH1 . ARG A 1 240 ? -28.843 12.718 -0.931 1.00 94.24 ? 240 ARG A NH1 1 ATOM 1845 N NH2 . ARG A 1 240 ? -29.550 11.985 -2.991 1.00 93.90 ? 240 ARG A NH2 1 ATOM 1846 N N . ASN A 1 241 ? -28.540 7.135 1.563 1.00 91.38 ? 241 ASN A N 1 ATOM 1847 C CA . ASN A 1 241 ? -27.143 6.914 1.977 1.00 91.01 ? 241 ASN A CA 1 ATOM 1848 C C . ASN A 1 241 ? -26.640 5.580 1.443 1.00 89.72 ? 241 ASN A C 1 ATOM 1849 O O . ASN A 1 241 ? -25.491 5.452 1.034 1.00 89.62 ? 241 ASN A O 1 ATOM 1850 C CB . ASN A 1 241 ? -26.972 6.950 3.511 1.00 91.88 ? 241 ASN A CB 1 ATOM 1851 C CG . ASN A 1 241 ? -25.556 7.377 3.948 1.00 95.03 ? 241 ASN A CG 1 ATOM 1852 O OD1 . ASN A 1 241 ? -25.144 8.481 3.649 1.00 96.17 ? 241 ASN A OD1 1 ATOM 1853 N ND2 . ASN A 1 241 ? -24.827 6.510 4.665 1.00 100.71 ? 241 ASN A ND2 1 ATOM 1854 N N . ARG A 1 242 ? -27.523 4.589 1.433 1.00 88.30 ? 242 ARG A N 1 ATOM 1855 C CA . ARG A 1 242 ? -27.147 3.237 1.070 1.00 86.68 ? 242 ARG A CA 1 ATOM 1856 C C . ARG A 1 242 ? -27.102 3.062 -0.413 1.00 86.07 ? 242 ARG A C 1 ATOM 1857 O O . ARG A 1 242 ? -26.269 2.325 -0.917 1.00 86.02 ? 242 ARG A O 1 ATOM 1858 C CB . ARG A 1 242 ? -28.110 2.232 1.674 1.00 86.38 ? 242 ARG A CB 1 ATOM 1859 C CG . ARG A 1 242 ? -27.927 2.098 3.155 1.00 84.91 ? 242 ARG A CG 1 ATOM 1860 C CD . ARG A 1 242 ? -29.083 1.388 3.795 1.00 82.49 ? 242 ARG A CD 1 ATOM 1861 N NE . ARG A 1 242 ? -29.068 1.597 5.231 1.00 79.69 ? 242 ARG A NE 1 ATOM 1862 C CZ . ARG A 1 242 ? -29.830 0.936 6.079 1.00 77.82 ? 242 ARG A CZ 1 ATOM 1863 N NH1 . ARG A 1 242 ? -30.653 0.015 5.637 1.00 76.60 ? 242 ARG A NH1 1 ATOM 1864 N NH2 . ARG A 1 242 ? -29.757 1.195 7.366 1.00 78.13 ? 242 ARG A NH2 1 ATOM 1865 N N . THR A 1 243 ? -27.995 3.743 -1.118 1.00 85.44 ? 243 THR A N 1 ATOM 1866 C CA . THR A 1 243 ? -27.993 3.665 -2.569 1.00 84.84 ? 243 THR A CA 1 ATOM 1867 C C . THR A 1 243 ? -26.718 4.311 -3.076 1.00 84.67 ? 243 THR A C 1 ATOM 1868 O O . THR A 1 243 ? -26.096 3.816 -4.009 1.00 84.85 ? 243 THR A O 1 ATOM 1869 C CB . THR A 1 243 ? -29.211 4.331 -3.200 1.00 84.59 ? 243 THR A CB 1 ATOM 1870 O OG1 . THR A 1 243 ? -30.387 3.588 -2.867 1.00 84.38 ? 243 THR A OG1 1 ATOM 1871 C CG2 . THR A 1 243 ? -29.066 4.318 -4.682 1.00 84.38 ? 243 THR A CG2 1 ATOM 1872 N N . LEU A 1 244 ? -26.306 5.395 -2.425 1.00 84.31 ? 244 LEU A N 1 ATOM 1873 C CA . LEU A 1 244 ? -25.069 6.072 -2.797 1.00 83.81 ? 244 LEU A CA 1 ATOM 1874 C C . LEU A 1 244 ? -23.865 5.249 -2.395 1.00 83.78 ? 244 LEU A C 1 ATOM 1875 O O . LEU A 1 244 ? -22.956 5.033 -3.187 1.00 84.00 ? 244 LEU A O 1 ATOM 1876 C CB . LEU A 1 244 ? -24.982 7.458 -2.165 1.00 83.55 ? 244 LEU A CB 1 ATOM 1877 C CG . LEU A 1 244 ? -26.117 8.436 -2.484 1.00 83.16 ? 244 LEU A CG 1 ATOM 1878 C CD1 . LEU A 1 244 ? -25.736 9.836 -2.039 1.00 82.42 ? 244 LEU A CD1 1 ATOM 1879 C CD2 . LEU A 1 244 ? -26.486 8.421 -3.964 1.00 82.59 ? 244 LEU A CD2 1 ATOM 1880 N N . ASN A 1 245 ? -23.849 4.778 -1.162 1.00 83.77 ? 245 ASN A N 1 ATOM 1881 C CA . ASN A 1 245 ? -22.735 3.953 -0.730 1.00 83.98 ? 245 ASN A CA 1 ATOM 1882 C C . ASN A 1 245 ? -22.505 2.792 -1.677 1.00 83.98 ? 245 ASN A C 1 ATOM 1883 O O . ASN A 1 245 ? -21.371 2.446 -1.998 1.00 83.96 ? 245 ASN A O 1 ATOM 1884 C CB . ASN A 1 245 ? -22.963 3.452 0.682 1.00 84.01 ? 245 ASN A CB 1 ATOM 1885 C CG . ASN A 1 245 ? -22.818 4.544 1.696 1.00 84.99 ? 245 ASN A CG 1 ATOM 1886 O OD1 . ASN A 1 245 ? -22.511 5.687 1.354 1.00 86.45 ? 245 ASN A OD1 1 ATOM 1887 N ND2 . ASN A 1 245 ? -23.036 4.209 2.958 1.00 86.02 ? 245 ASN A ND2 1 ATOM 1888 N N . LEU A 1 246 ? -23.593 2.200 -2.143 1.00 84.03 ? 246 LEU A N 1 ATOM 1889 C CA . LEU A 1 246 ? -23.480 1.096 -3.054 1.00 84.04 ? 246 LEU A CA 1 ATOM 1890 C C . LEU A 1 246 ? -22.869 1.599 -4.326 1.00 84.21 ? 246 LEU A C 1 ATOM 1891 O O . LEU A 1 246 ? -22.058 0.924 -4.938 1.00 84.29 ? 246 LEU A O 1 ATOM 1892 C CB . LEU A 1 246 ? -24.843 0.490 -3.345 1.00 83.91 ? 246 LEU A CB 1 ATOM 1893 C CG . LEU A 1 246 ? -24.819 -0.715 -4.284 1.00 83.50 ? 246 LEU A CG 1 ATOM 1894 C CD1 . LEU A 1 246 ? -24.383 -1.985 -3.539 1.00 82.60 ? 246 LEU A CD1 1 ATOM 1895 C CD2 . LEU A 1 246 ? -26.183 -0.916 -4.951 1.00 82.55 ? 246 LEU A CD2 1 ATOM 1896 N N . ALA A 1 247 ? -23.250 2.801 -4.720 1.00 84.60 ? 247 ALA A N 1 ATOM 1897 C CA . ALA A 1 247 ? -22.723 3.363 -5.947 1.00 85.32 ? 247 ALA A CA 1 ATOM 1898 C C . ALA A 1 247 ? -21.222 3.556 -5.809 1.00 85.84 ? 247 ALA A C 1 ATOM 1899 O O . ALA A 1 247 ? -20.444 3.039 -6.607 1.00 85.86 ? 247 ALA A O 1 ATOM 1900 C CB . ALA A 1 247 ? -23.412 4.671 -6.287 1.00 85.07 ? 247 ALA A CB 1 ATOM 1901 N N . LYS A 1 248 ? -20.805 4.279 -4.782 1.00 86.58 ? 248 LYS A N 1 ATOM 1902 C CA . LYS A 1 248 ? -19.390 4.444 -4.585 1.00 87.50 ? 248 LYS A CA 1 ATOM 1903 C C . LYS A 1 248 ? -18.718 3.076 -4.659 1.00 87.77 ? 248 LYS A C 1 ATOM 1904 O O . LYS A 1 248 ? -17.825 2.882 -5.479 1.00 87.96 ? 248 LYS A O 1 ATOM 1905 C CB . LYS A 1 248 ? -19.080 5.156 -3.263 1.00 87.86 ? 248 LYS A CB 1 ATOM 1906 C CG . LYS A 1 248 ? -17.691 4.808 -2.711 1.00 89.34 ? 248 LYS A CG 1 ATOM 1907 C CD . LYS A 1 248 ? -16.994 5.963 -1.998 1.00 91.33 ? 248 LYS A CD 1 ATOM 1908 C CE . LYS A 1 248 ? -15.709 5.449 -1.336 1.00 92.55 ? 248 LYS A CE 1 ATOM 1909 N NZ . LYS A 1 248 ? -14.688 6.511 -1.107 1.00 93.58 ? 248 LYS A NZ 1 ATOM 1910 N N . LEU A 1 249 ? -19.168 2.128 -3.829 1.00 88.11 ? 249 LEU A N 1 ATOM 1911 C CA . LEU A 1 249 ? -18.548 0.798 -3.730 1.00 88.20 ? 249 LEU A CA 1 ATOM 1912 C C . LEU A 1 249 ? -18.412 0.039 -5.044 1.00 88.42 ? 249 LEU A C 1 ATOM 1913 O O . LEU A 1 249 ? -17.712 -0.960 -5.112 1.00 88.45 ? 249 LEU A O 1 ATOM 1914 C CB . LEU A 1 249 ? -19.313 -0.074 -2.751 1.00 88.04 ? 249 LEU A CB 1 ATOM 1915 C CG . LEU A 1 249 ? -18.949 0.069 -1.288 1.00 88.42 ? 249 LEU A CG 1 ATOM 1916 C CD1 . LEU A 1 249 ? -20.123 -0.364 -0.451 1.00 89.54 ? 249 LEU A CD1 1 ATOM 1917 C CD2 . LEU A 1 249 ? -17.732 -0.768 -0.953 1.00 88.82 ? 249 LEU A CD2 1 ATOM 1918 N N . THR A 1 250 ? -19.087 0.485 -6.088 1.00 88.80 ? 250 THR A N 1 ATOM 1919 C CA . THR A 1 250 ? -18.918 -0.166 -7.373 1.00 89.37 ? 250 THR A CA 1 ATOM 1920 C C . THR A 1 250 ? -18.496 0.838 -8.420 1.00 89.97 ? 250 THR A C 1 ATOM 1921 O O . THR A 1 250 ? -18.758 0.652 -9.597 1.00 89.68 ? 250 THR A O 1 ATOM 1922 C CB . THR A 1 250 ? -20.208 -0.826 -7.831 1.00 89.48 ? 250 THR A CB 1 ATOM 1923 O OG1 . THR A 1 250 ? -21.151 0.183 -8.212 1.00 88.98 ? 250 THR A OG1 1 ATOM 1924 C CG2 . THR A 1 250 ? -20.789 -1.676 -6.706 1.00 89.26 ? 250 THR A CG2 1 ATOM 1925 N N . GLY A 1 251 ? -17.844 1.908 -7.971 1.00 90.96 ? 251 GLY A N 1 ATOM 1926 C CA . GLY A 1 251 ? -17.464 3.025 -8.833 1.00 92.22 ? 251 GLY A CA 1 ATOM 1927 C C . GLY A 1 251 ? -18.621 3.556 -9.666 1.00 93.21 ? 251 GLY A C 1 ATOM 1928 O O . GLY A 1 251 ? -18.500 3.761 -10.874 1.00 93.20 ? 251 GLY A O 1 ATOM 1929 N N . CYS A 1 252 ? -19.757 3.794 -9.034 1.00 94.26 ? 252 CYS A N 1 ATOM 1930 C CA . CYS A 1 252 ? -20.905 4.215 -9.805 1.00 95.36 ? 252 CYS A CA 1 ATOM 1931 C C . CYS A 1 252 ? -21.362 5.622 -9.470 1.00 96.13 ? 252 CYS A C 1 ATOM 1932 O O . CYS A 1 252 ? -22.378 6.075 -10.001 1.00 96.43 ? 252 CYS A O 1 ATOM 1933 C CB . CYS A 1 252 ? -22.056 3.219 -9.655 1.00 95.47 ? 252 CYS A CB 1 ATOM 1934 S SG . CYS A 1 252 ? -22.075 1.864 -10.888 1.00 95.55 ? 252 CYS A SG 1 ATOM 1935 N N . SER A 1 253 ? -20.607 6.314 -8.619 1.00 96.86 ? 253 SER A N 1 ATOM 1936 C CA . SER A 1 253 ? -20.965 7.667 -8.201 1.00 97.78 ? 253 SER A CA 1 ATOM 1937 C C . SER A 1 253 ? -21.212 8.585 -9.412 1.00 98.61 ? 253 SER A C 1 ATOM 1938 O O . SER A 1 253 ? -20.685 8.340 -10.488 1.00 98.73 ? 253 SER A O 1 ATOM 1939 C CB . SER A 1 253 ? -19.884 8.219 -7.277 1.00 97.77 ? 253 SER A CB 1 ATOM 1940 O OG . SER A 1 253 ? -19.581 7.292 -6.245 1.00 97.14 ? 253 SER A OG 1 ATOM 1941 N N . ARG A 1 254 ? -22.027 9.627 -9.259 1.00 99.81 ? 254 ARG A N 1 ATOM 1942 C CA . ARG A 1 254 ? -22.412 10.422 -10.433 1.00 101.03 ? 254 ARG A CA 1 ATOM 1943 C C . ARG A 1 254 ? -23.032 11.792 -10.130 1.00 102.06 ? 254 ARG A C 1 ATOM 1944 O O . ARG A 1 254 ? -23.114 12.223 -8.980 1.00 102.07 ? 254 ARG A O 1 ATOM 1945 C CB . ARG A 1 254 ? -23.379 9.615 -11.313 1.00 100.92 ? 254 ARG A CB 1 ATOM 1946 C CG . ARG A 1 254 ? -22.935 9.435 -12.751 1.00 100.16 ? 254 ARG A CG 1 ATOM 1947 C CD . ARG A 1 254 ? -21.536 8.868 -12.764 1.00 98.23 ? 254 ARG A CD 1 ATOM 1948 N NE . ARG A 1 254 ? -21.384 7.832 -13.769 1.00 96.67 ? 254 ARG A NE 1 ATOM 1949 C CZ . ARG A 1 254 ? -20.685 6.720 -13.580 1.00 95.52 ? 254 ARG A CZ 1 ATOM 1950 N NH1 . ARG A 1 254 ? -20.596 5.821 -14.550 1.00 95.62 ? 254 ARG A NH1 1 ATOM 1951 N NH2 . ARG A 1 254 ? -20.086 6.494 -12.422 1.00 94.14 ? 254 ARG A NH2 1 ATOM 1952 N N . GLU A 1 255 ? -23.457 12.475 -11.190 1.00 103.30 ? 255 GLU A N 1 ATOM 1953 C CA . GLU A 1 255 ? -24.148 13.744 -11.060 1.00 104.47 ? 255 GLU A CA 1 ATOM 1954 C C . GLU A 1 255 ? -25.622 13.531 -11.383 1.00 104.59 ? 255 GLU A C 1 ATOM 1955 O O . GLU A 1 255 ? -26.470 13.710 -10.514 1.00 104.78 ? 255 GLU A O 1 ATOM 1956 C CB . GLU A 1 255 ? -23.525 14.806 -11.979 1.00 104.96 ? 255 GLU A CB 1 ATOM 1957 C CG . GLU A 1 255 ? -24.322 16.137 -12.092 1.00 106.93 ? 255 GLU A CG 1 ATOM 1958 C CD . GLU A 1 255 ? -23.640 17.325 -11.415 1.00 109.25 ? 255 GLU A CD 1 ATOM 1959 O OE1 . GLU A 1 255 ? -22.510 17.166 -10.890 1.00 110.00 ? 255 GLU A OE1 1 ATOM 1960 O OE2 . GLU A 1 255 ? -24.244 18.423 -11.419 1.00 110.08 ? 255 GLU A OE2 1 ATOM 1961 N N . ASN A 1 256 ? -25.930 13.151 -12.623 1.00 104.79 ? 256 ASN A N 1 ATOM 1962 C CA . ASN A 1 256 ? -27.309 12.840 -12.982 1.00 104.92 ? 256 ASN A CA 1 ATOM 1963 C C . ASN A 1 256 ? -27.628 11.545 -12.253 1.00 105.02 ? 256 ASN A C 1 ATOM 1964 O O . ASN A 1 256 ? -26.995 10.513 -12.471 1.00 105.12 ? 256 ASN A O 1 ATOM 1965 C CB . ASN A 1 256 ? -27.494 12.717 -14.507 1.00 104.95 ? 256 ASN A CB 1 ATOM 1966 C CG . ASN A 1 256 ? -28.945 12.954 -14.968 1.00 104.70 ? 256 ASN A CG 1 ATOM 1967 O OD1 . ASN A 1 256 ? -29.649 12.020 -15.326 1.00 104.28 ? 256 ASN A OD1 1 ATOM 1968 N ND2 . ASN A 1 256 ? -29.375 14.207 -14.981 1.00 104.35 ? 256 ASN A ND2 1 ATOM 1969 N N . GLU A 1 257 ? -28.561 11.630 -11.319 1.00 105.01 ? 257 GLU A N 1 ATOM 1970 C CA . GLU A 1 257 ? -28.926 10.478 -10.524 1.00 104.90 ? 257 GLU A CA 1 ATOM 1971 C C . GLU A 1 257 ? -29.274 9.322 -11.430 1.00 104.58 ? 257 GLU A C 1 ATOM 1972 O O . GLU A 1 257 ? -28.765 8.225 -11.251 1.00 104.81 ? 257 GLU A O 1 ATOM 1973 C CB . GLU A 1 257 ? -30.122 10.790 -9.629 1.00 105.25 ? 257 GLU A CB 1 ATOM 1974 C CG . GLU A 1 257 ? -29.782 11.547 -8.348 1.00 105.82 ? 257 GLU A CG 1 ATOM 1975 C CD . GLU A 1 257 ? -30.810 11.312 -7.252 1.00 105.93 ? 257 GLU A CD 1 ATOM 1976 O OE1 . GLU A 1 257 ? -31.904 10.784 -7.566 1.00 105.20 ? 257 GLU A OE1 1 ATOM 1977 O OE2 . GLU A 1 257 ? -30.513 11.645 -6.080 1.00 106.19 ? 257 GLU A OE2 1 ATOM 1978 N N . THR A 1 258 ? -30.146 9.564 -12.403 1.00 104.06 ? 258 THR A N 1 ATOM 1979 C CA . THR A 1 258 ? -30.554 8.511 -13.317 1.00 103.56 ? 258 THR A CA 1 ATOM 1980 C C . THR A 1 258 ? -29.330 7.771 -13.860 1.00 103.22 ? 258 THR A C 1 ATOM 1981 O O . THR A 1 258 ? -29.377 6.564 -14.124 1.00 103.18 ? 258 THR A O 1 ATOM 1982 C CB . THR A 1 258 ? -31.397 9.073 -14.466 1.00 103.55 ? 258 THR A CB 1 ATOM 1983 O OG1 . THR A 1 258 ? -32.435 9.891 -13.919 1.00 103.46 ? 258 THR A OG1 1 ATOM 1984 C CG2 . THR A 1 258 ? -32.018 7.950 -15.292 1.00 103.50 ? 258 THR A CG2 1 ATOM 1985 N N . GLU A 1 259 ? -28.224 8.489 -14.010 1.00 102.63 ? 259 GLU A N 1 ATOM 1986 C CA . GLU A 1 259 ? -27.014 7.858 -14.511 1.00 102.17 ? 259 GLU A CA 1 ATOM 1987 C C . GLU A 1 259 ? -26.478 6.797 -13.549 1.00 101.34 ? 259 GLU A C 1 ATOM 1988 O O . GLU A 1 259 ? -26.070 5.714 -13.976 1.00 101.36 ? 259 GLU A O 1 ATOM 1989 C CB . GLU A 1 259 ? -25.951 8.901 -14.852 1.00 102.55 ? 259 GLU A CB 1 ATOM 1990 C CG . GLU A 1 259 ? -26.161 9.554 -16.216 1.00 103.34 ? 259 GLU A CG 1 ATOM 1991 C CD . GLU A 1 259 ? -25.078 10.560 -16.538 1.00 104.74 ? 259 GLU A CD 1 ATOM 1992 O OE1 . GLU A 1 259 ? -25.419 11.696 -16.931 1.00 105.29 ? 259 GLU A OE1 1 ATOM 1993 O OE2 . GLU A 1 259 ? -23.885 10.218 -16.379 1.00 105.09 ? 259 GLU A OE2 1 ATOM 1994 N N . ILE A 1 260 ? -26.501 7.090 -12.255 1.00 100.26 ? 260 ILE A N 1 ATOM 1995 C CA . ILE A 1 260 ? -26.100 6.091 -11.278 1.00 99.12 ? 260 ILE A CA 1 ATOM 1996 C C . ILE A 1 260 ? -26.879 4.800 -11.452 1.00 98.57 ? 260 ILE A C 1 ATOM 1997 O O . ILE A 1 260 ? -26.345 3.720 -11.251 1.00 98.38 ? 260 ILE A O 1 ATOM 1998 C CB . ILE A 1 260 ? -26.346 6.538 -9.866 1.00 98.87 ? 260 ILE A CB 1 ATOM 1999 C CG1 . ILE A 1 260 ? -25.906 7.980 -9.676 1.00 98.79 ? 260 ILE A CG1 1 ATOM 2000 C CG2 . ILE A 1 260 ? -25.601 5.631 -8.938 1.00 99.06 ? 260 ILE A CG2 1 ATOM 2001 C CD1 . ILE A 1 260 ? -25.636 8.344 -8.230 1.00 98.53 ? 260 ILE A CD1 1 ATOM 2002 N N . ILE A 1 261 ? -28.155 4.906 -11.789 1.00 97.96 ? 261 ILE A N 1 ATOM 2003 C CA . ILE A 1 261 ? -28.932 3.706 -12.039 1.00 97.52 ? 261 ILE A CA 1 ATOM 2004 C C . ILE A 1 261 ? -28.453 3.057 -13.324 1.00 97.23 ? 261 ILE A C 1 ATOM 2005 O O . ILE A 1 261 ? -28.329 1.841 -13.384 1.00 97.31 ? 261 ILE A O 1 ATOM 2006 C CB . ILE A 1 261 ? -30.432 3.983 -12.135 1.00 97.58 ? 261 ILE A CB 1 ATOM 2007 C CG1 . ILE A 1 261 ? -30.912 4.712 -10.883 1.00 97.46 ? 261 ILE A CG1 1 ATOM 2008 C CG2 . ILE A 1 261 ? -31.194 2.683 -12.304 1.00 97.43 ? 261 ILE A CG2 1 ATOM 2009 C CD1 . ILE A 1 261 ? -30.438 4.089 -9.627 1.00 97.26 ? 261 ILE A CD1 1 ATOM 2010 N N . LYS A 1 262 ? -28.173 3.873 -14.343 1.00 96.80 ? 262 LYS A N 1 ATOM 2011 C CA . LYS A 1 262 ? -27.635 3.385 -15.627 1.00 96.20 ? 262 LYS A CA 1 ATOM 2012 C C . LYS A 1 262 ? -26.365 2.586 -15.382 1.00 95.42 ? 262 LYS A C 1 ATOM 2013 O O . LYS A 1 262 ? -26.226 1.462 -15.852 1.00 95.20 ? 262 LYS A O 1 ATOM 2014 C CB . LYS A 1 262 ? -27.317 4.552 -16.569 1.00 96.37 ? 262 LYS A CB 1 ATOM 2015 C CG . LYS A 1 262 ? -27.239 4.178 -18.050 1.00 97.14 ? 262 LYS A CG 1 ATOM 2016 C CD . LYS A 1 262 ? -28.634 4.131 -18.671 1.00 98.49 ? 262 LYS A CD 1 ATOM 2017 C CE . LYS A 1 262 ? -28.595 4.266 -20.198 1.00 98.87 ? 262 LYS A CE 1 ATOM 2018 N NZ . LYS A 1 262 ? -28.016 3.069 -20.850 1.00 99.58 ? 262 LYS A NZ 1 ATOM 2019 N N . CYS A 1 263 ? -25.451 3.194 -14.636 1.00 94.53 ? 263 CYS A N 1 ATOM 2020 C CA . CYS A 1 263 ? -24.231 2.554 -14.207 1.00 93.92 ? 263 CYS A CA 1 ATOM 2021 C C . CYS A 1 263 ? -24.527 1.197 -13.611 1.00 93.32 ? 263 CYS A C 1 ATOM 2022 O O . CYS A 1 263 ? -24.023 0.183 -14.082 1.00 93.47 ? 263 CYS A O 1 ATOM 2023 C CB . CYS A 1 263 ? -23.562 3.401 -13.128 1.00 94.13 ? 263 CYS A CB 1 ATOM 2024 S SG . CYS A 1 263 ? -21.904 2.844 -12.664 1.00 95.39 ? 263 CYS A SG 1 ATOM 2025 N N . LEU A 1 264 ? -25.353 1.188 -12.568 1.00 92.56 ? 264 LEU A N 1 ATOM 2026 C CA . LEU A 1 264 ? -25.595 -0.008 -11.762 1.00 91.55 ? 264 LEU A CA 1 ATOM 2027 C C . LEU A 1 264 ? -26.363 -1.037 -12.551 1.00 91.13 ? 264 LEU A C 1 ATOM 2028 O O . LEU A 1 264 ? -26.207 -2.234 -12.355 1.00 91.04 ? 264 LEU A O 1 ATOM 2029 C CB . LEU A 1 264 ? -26.393 0.346 -10.518 1.00 91.35 ? 264 LEU A CB 1 ATOM 2030 C CG . LEU A 1 264 ? -25.649 1.009 -9.379 1.00 90.97 ? 264 LEU A CG 1 ATOM 2031 C CD1 . LEU A 1 264 ? -26.639 1.588 -8.402 1.00 90.69 ? 264 LEU A CD1 1 ATOM 2032 C CD2 . LEU A 1 264 ? -24.756 -0.004 -8.709 1.00 91.53 ? 264 LEU A CD2 1 ATOM 2033 N N . ARG A 1 265 ? -27.214 -0.560 -13.438 1.00 90.69 ? 265 ARG A N 1 ATOM 2034 C CA . ARG A 1 265 ? -27.938 -1.459 -14.299 1.00 90.55 ? 265 ARG A CA 1 ATOM 2035 C C . ARG A 1 265 ? -26.987 -2.300 -15.111 1.00 90.08 ? 265 ARG A C 1 ATOM 2036 O O . ARG A 1 265 ? -27.418 -3.265 -15.733 1.00 90.12 ? 265 ARG A O 1 ATOM 2037 C CB . ARG A 1 265 ? -28.833 -0.695 -15.261 1.00 90.77 ? 265 ARG A CB 1 ATOM 2038 C CG . ARG A 1 265 ? -30.194 -0.404 -14.713 1.00 91.94 ? 265 ARG A CG 1 ATOM 2039 C CD . ARG A 1 265 ? -31.215 -0.398 -15.826 1.00 94.73 ? 265 ARG A CD 1 ATOM 2040 N NE . ARG A 1 265 ? -32.529 0.000 -15.336 1.00 96.81 ? 265 ARG A NE 1 ATOM 2041 C CZ . ARG A 1 265 ? -32.931 1.261 -15.266 1.00 97.46 ? 265 ARG A CZ 1 ATOM 2042 N NH1 . ARG A 1 265 ? -34.149 1.550 -14.804 1.00 97.18 ? 265 ARG A NH1 1 ATOM 2043 N NH2 . ARG A 1 265 ? -32.098 2.222 -15.662 1.00 97.44 ? 265 ARG A NH2 1 ATOM 2044 N N . ASN A 1 266 ? -25.706 -1.932 -15.124 1.00 89.34 ? 266 ASN A N 1 ATOM 2045 C CA . ASN A 1 266 ? -24.737 -2.638 -15.965 1.00 88.70 ? 266 ASN A CA 1 ATOM 2046 C C . ASN A 1 266 ? -23.742 -3.526 -15.247 1.00 88.03 ? 266 ASN A C 1 ATOM 2047 O O . ASN A 1 266 ? -23.100 -4.350 -15.874 1.00 88.29 ? 266 ASN A O 1 ATOM 2048 C CB . ASN A 1 266 ? -24.032 -1.694 -16.933 1.00 88.80 ? 266 ASN A CB 1 ATOM 2049 C CG . ASN A 1 266 ? -24.836 -1.484 -18.201 1.00 90.05 ? 266 ASN A CG 1 ATOM 2050 O OD1 . ASN A 1 266 ? -25.042 -2.412 -18.984 1.00 90.46 ? 266 ASN A OD1 1 ATOM 2051 N ND2 . ASN A 1 266 ? -25.321 -0.267 -18.398 1.00 91.35 ? 266 ASN A ND2 1 ATOM 2052 N N . LYS A 1 267 ? -23.625 -3.384 -13.935 1.00 87.20 ? 267 LYS A N 1 ATOM 2053 C CA . LYS A 1 267 ? -22.767 -4.277 -13.167 1.00 86.32 ? 267 LYS A CA 1 ATOM 2054 C C . LYS A 1 267 ? -23.319 -5.717 -13.132 1.00 85.70 ? 267 LYS A C 1 ATOM 2055 O O . LYS A 1 267 ? -24.462 -5.971 -13.486 1.00 85.11 ? 267 LYS A O 1 ATOM 2056 C CB . LYS A 1 267 ? -22.573 -3.712 -11.763 1.00 86.22 ? 267 LYS A CB 1 ATOM 2057 C CG . LYS A 1 267 ? -22.004 -2.297 -11.754 1.00 86.73 ? 267 LYS A CG 1 ATOM 2058 C CD . LYS A 1 267 ? -20.581 -2.258 -11.178 1.00 87.74 ? 267 LYS A CD 1 ATOM 2059 C CE . LYS A 1 267 ? -19.503 -2.386 -12.244 1.00 87.69 ? 267 LYS A CE 1 ATOM 2060 N NZ . LYS A 1 267 ? -19.276 -1.100 -12.917 1.00 87.34 ? 267 LYS A NZ 1 ATOM 2061 N N . ASP A 1 268 ? -22.490 -6.667 -12.726 1.00 85.57 ? 268 ASP A N 1 ATOM 2062 C CA A ASP A 1 268 ? -22.943 -8.037 -12.603 0.50 85.34 ? 268 ASP A CA 1 ATOM 2063 C CA B ASP A 1 268 ? -22.925 -8.060 -12.590 0.50 85.37 ? 268 ASP A CA 1 ATOM 2064 C C . ASP A 1 268 ? -23.628 -8.278 -11.264 1.00 85.22 ? 268 ASP A C 1 ATOM 2065 O O . ASP A 1 268 ? -23.122 -7.891 -10.207 1.00 85.01 ? 268 ASP A O 1 ATOM 2066 C CB A ASP A 1 268 ? -21.783 -9.016 -12.810 0.50 85.37 ? 268 ASP A CB 1 ATOM 2067 C CB B ASP A 1 268 ? -21.742 -9.044 -12.700 0.50 85.40 ? 268 ASP A CB 1 ATOM 2068 C CG A ASP A 1 268 ? -21.599 -9.394 -14.266 0.50 85.20 ? 268 ASP A CG 1 ATOM 2069 C CG B ASP A 1 268 ? -22.003 -10.383 -11.969 0.50 85.39 ? 268 ASP A CG 1 ATOM 2070 O OD1 A ASP A 1 268 ? -20.530 -9.924 -14.626 0.50 84.86 ? 268 ASP A OD1 1 ATOM 2071 O OD1 B ASP A 1 268 ? -22.922 -11.128 -12.383 0.50 85.23 ? 268 ASP A OD1 1 ATOM 2072 O OD2 A ASP A 1 268 ? -22.537 -9.158 -15.054 0.50 85.55 ? 268 ASP A OD2 1 ATOM 2073 O OD2 B ASP A 1 268 ? -21.280 -10.697 -10.994 0.50 85.31 ? 268 ASP A OD2 1 ATOM 2074 N N . PRO A 1 269 ? -24.796 -8.911 -11.312 1.00 85.14 ? 269 PRO A N 1 ATOM 2075 C CA . PRO A 1 269 ? -25.516 -9.264 -10.120 1.00 85.15 ? 269 PRO A CA 1 ATOM 2076 C C . PRO A 1 269 ? -24.556 -9.494 -8.962 1.00 85.41 ? 269 PRO A C 1 ATOM 2077 O O . PRO A 1 269 ? -24.720 -8.907 -7.903 1.00 85.56 ? 269 PRO A O 1 ATOM 2078 C CB . PRO A 1 269 ? -26.188 -10.574 -10.520 1.00 84.97 ? 269 PRO A CB 1 ATOM 2079 C CG . PRO A 1 269 ? -26.324 -10.497 -12.035 1.00 84.87 ? 269 PRO A CG 1 ATOM 2080 C CD . PRO A 1 269 ? -25.500 -9.351 -12.527 1.00 85.07 ? 269 PRO A CD 1 ATOM 2081 N N . GLN A 1 270 ? -23.553 -10.333 -9.178 1.00 85.82 ? 270 GLN A N 1 ATOM 2082 C CA . GLN A 1 270 ? -22.664 -10.819 -8.102 1.00 86.36 ? 270 GLN A CA 1 ATOM 2083 C C . GLN A 1 270 ? -21.858 -9.673 -7.510 1.00 86.06 ? 270 GLN A C 1 ATOM 2084 O O . GLN A 1 270 ? -21.481 -9.697 -6.335 1.00 85.89 ? 270 GLN A O 1 ATOM 2085 C CB . GLN A 1 270 ? -21.707 -11.884 -8.626 1.00 86.78 ? 270 GLN A CB 1 ATOM 2086 C CG . GLN A 1 270 ? -22.355 -12.826 -9.514 1.00 89.13 ? 270 GLN A CG 1 ATOM 2087 C CD . GLN A 1 270 ? -22.921 -13.922 -8.814 1.00 91.77 ? 270 GLN A CD 1 ATOM 2088 O OE1 . GLN A 1 270 ? -22.163 -14.697 -8.314 1.00 92.80 ? 270 GLN A OE1 1 ATOM 2089 N NE2 . GLN A 1 270 ? -24.250 -14.073 -8.812 1.00 91.92 ? 270 GLN A NE2 1 ATOM 2090 N N . GLU A 1 271 ? -21.579 -8.679 -8.345 1.00 86.02 ? 271 GLU A N 1 ATOM 2091 C CA . GLU A 1 271 ? -20.805 -7.511 -7.936 1.00 86.02 ? 271 GLU A CA 1 ATOM 2092 C C . GLU A 1 271 ? -21.626 -6.613 -7.011 1.00 85.44 ? 271 GLU A C 1 ATOM 2093 O O . GLU A 1 271 ? -21.106 -5.986 -6.084 1.00 85.22 ? 271 GLU A O 1 ATOM 2094 C CB . GLU A 1 271 ? -20.379 -6.732 -9.178 1.00 86.39 ? 271 GLU A CB 1 ATOM 2095 C CG . GLU A 1 271 ? -19.046 -6.004 -9.041 1.00 87.82 ? 271 GLU A CG 1 ATOM 2096 C CD . GLU A 1 271 ? -18.699 -5.188 -10.286 1.00 89.70 ? 271 GLU A CD 1 ATOM 2097 O OE1 . GLU A 1 271 ? -18.989 -5.652 -11.430 1.00 89.28 ? 271 GLU A OE1 1 ATOM 2098 O OE2 . GLU A 1 271 ? -18.138 -4.076 -10.100 1.00 90.48 ? 271 GLU A OE2 1 ATOM 2099 N N . ILE A 1 272 ? -22.920 -6.554 -7.294 1.00 84.80 ? 272 ILE A N 1 ATOM 2100 C CA . ILE A 1 272 ? -23.878 -5.906 -6.420 1.00 84.08 ? 272 ILE A CA 1 ATOM 2101 C C . ILE A 1 272 ? -24.069 -6.702 -5.128 1.00 84.00 ? 272 ILE A C 1 ATOM 2102 O O . ILE A 1 272 ? -23.927 -6.160 -4.038 1.00 83.99 ? 272 ILE A O 1 ATOM 2103 C CB . ILE A 1 272 ? -25.222 -5.757 -7.124 1.00 83.70 ? 272 ILE A CB 1 ATOM 2104 C CG1 . ILE A 1 272 ? -25.213 -4.511 -7.990 1.00 83.29 ? 272 ILE A CG1 1 ATOM 2105 C CG2 . ILE A 1 272 ? -26.325 -5.655 -6.123 1.00 83.60 ? 272 ILE A CG2 1 ATOM 2106 C CD1 . ILE A 1 272 ? -26.193 -4.565 -9.113 1.00 82.55 ? 272 ILE A CD1 1 ATOM 2107 N N . LEU A 1 273 ? -24.382 -7.988 -5.257 1.00 83.88 ? 273 LEU A N 1 ATOM 2108 C CA . LEU A 1 273 ? -24.590 -8.859 -4.113 1.00 83.95 ? 273 LEU A CA 1 ATOM 2109 C C . LEU A 1 273 ? -23.451 -8.822 -3.127 1.00 84.39 ? 273 LEU A C 1 ATOM 2110 O O . LEU A 1 273 ? -23.641 -9.040 -1.932 1.00 84.38 ? 273 LEU A O 1 ATOM 2111 C CB . LEU A 1 273 ? -24.760 -10.286 -4.577 1.00 83.64 ? 273 LEU A CB 1 ATOM 2112 C CG . LEU A 1 273 ? -26.152 -10.540 -5.097 1.00 83.73 ? 273 LEU A CG 1 ATOM 2113 C CD1 . LEU A 1 273 ? -26.239 -11.927 -5.688 1.00 84.86 ? 273 LEU A CD1 1 ATOM 2114 C CD2 . LEU A 1 273 ? -27.117 -10.376 -3.943 1.00 84.48 ? 273 LEU A CD2 1 ATOM 2115 N N . LEU A 1 274 ? -22.259 -8.552 -3.628 1.00 85.16 ? 274 LEU A N 1 ATOM 2116 C CA . LEU A 1 274 ? -21.086 -8.610 -2.788 1.00 86.09 ? 274 LEU A CA 1 ATOM 2117 C C . LEU A 1 274 ? -20.996 -7.410 -1.872 1.00 86.49 ? 274 LEU A C 1 ATOM 2118 O O . LEU A 1 274 ? -20.757 -7.554 -0.677 1.00 86.82 ? 274 LEU A O 1 ATOM 2119 C CB . LEU A 1 274 ? -19.828 -8.680 -3.636 1.00 86.37 ? 274 LEU A CB 1 ATOM 2120 C CG . LEU A 1 274 ? -18.738 -9.354 -2.809 1.00 87.01 ? 274 LEU A CG 1 ATOM 2121 C CD1 . LEU A 1 274 ? -18.911 -10.876 -2.966 1.00 87.28 ? 274 LEU A CD1 1 ATOM 2122 C CD2 . LEU A 1 274 ? -17.319 -8.862 -3.190 1.00 86.87 ? 274 LEU A CD2 1 ATOM 2123 N N . ASN A 1 275 ? -21.201 -6.232 -2.447 1.00 87.00 ? 275 ASN A N 1 ATOM 2124 C CA . ASN A 1 275 ? -21.127 -4.972 -1.720 1.00 87.56 ? 275 ASN A CA 1 ATOM 2125 C C . ASN A 1 275 ? -22.293 -4.670 -0.791 1.00 87.86 ? 275 ASN A C 1 ATOM 2126 O O . ASN A 1 275 ? -22.127 -3.954 0.195 1.00 87.96 ? 275 ASN A O 1 ATOM 2127 C CB . ASN A 1 275 ? -20.971 -3.826 -2.706 1.00 87.69 ? 275 ASN A CB 1 ATOM 2128 C CG . ASN A 1 275 ? -19.648 -3.869 -3.431 1.00 87.90 ? 275 ASN A CG 1 ATOM 2129 O OD1 . ASN A 1 275 ? -19.603 -4.070 -4.652 1.00 88.68 ? 275 ASN A OD1 1 ATOM 2130 N ND2 . ASN A 1 275 ? -18.555 -3.692 -2.683 1.00 87.99 ? 275 ASN A ND2 1 ATOM 2131 N N . GLU A 1 276 ? -23.467 -5.206 -1.110 1.00 88.26 ? 276 GLU A N 1 ATOM 2132 C CA . GLU A 1 276 ? -24.640 -5.059 -0.254 1.00 88.53 ? 276 GLU A CA 1 ATOM 2133 C C . GLU A 1 276 ? -24.256 -5.102 1.213 1.00 88.83 ? 276 GLU A C 1 ATOM 2134 O O . GLU A 1 276 ? -24.612 -4.212 1.986 1.00 88.72 ? 276 GLU A O 1 ATOM 2135 C CB . GLU A 1 276 ? -25.638 -6.170 -0.528 1.00 88.44 ? 276 GLU A CB 1 ATOM 2136 C CG . GLU A 1 276 ? -26.454 -5.987 -1.778 1.00 88.39 ? 276 GLU A CG 1 ATOM 2137 C CD . GLU A 1 276 ? -27.576 -7.004 -1.873 1.00 88.76 ? 276 GLU A CD 1 ATOM 2138 O OE1 . GLU A 1 276 ? -27.759 -7.794 -0.918 1.00 88.96 ? 276 GLU A OE1 1 ATOM 2139 O OE2 . GLU A 1 276 ? -28.274 -7.015 -2.907 1.00 88.39 ? 276 GLU A OE2 1 ATOM 2140 N N . ALA A 1 277 ? -23.517 -6.137 1.590 1.00 89.23 ? 277 ALA A N 1 ATOM 2141 C CA . ALA A 1 277 ? -23.141 -6.302 2.976 1.00 89.84 ? 277 ALA A CA 1 ATOM 2142 C C . ALA A 1 277 ? -22.507 -5.033 3.562 1.00 90.30 ? 277 ALA A C 1 ATOM 2143 O O . ALA A 1 277 ? -22.538 -4.835 4.776 1.00 90.41 ? 277 ALA A O 1 ATOM 2144 C CB . ALA A 1 277 ? -22.222 -7.508 3.139 1.00 89.70 ? 277 ALA A CB 1 ATOM 2145 N N . PHE A 1 278 ? -21.976 -4.157 2.704 1.00 90.88 ? 278 PHE A N 1 ATOM 2146 C CA . PHE A 1 278 ? -21.082 -3.070 3.168 1.00 91.50 ? 278 PHE A CA 1 ATOM 2147 C C . PHE A 1 278 ? -21.652 -1.648 3.178 1.00 91.55 ? 278 PHE A C 1 ATOM 2148 O O . PHE A 1 278 ? -20.963 -0.722 3.600 1.00 91.68 ? 278 PHE A O 1 ATOM 2149 C CB . PHE A 1 278 ? -19.740 -3.071 2.393 1.00 91.56 ? 278 PHE A CB 1 ATOM 2150 C CG . PHE A 1 278 ? -18.992 -4.383 2.458 1.00 92.82 ? 278 PHE A CG 1 ATOM 2151 C CD1 . PHE A 1 278 ? -18.773 -5.134 1.305 1.00 93.54 ? 278 PHE A CD1 1 ATOM 2152 C CD2 . PHE A 1 278 ? -18.523 -4.880 3.677 1.00 93.70 ? 278 PHE A CD2 1 ATOM 2153 C CE1 . PHE A 1 278 ? -18.098 -6.357 1.358 1.00 93.89 ? 278 PHE A CE1 1 ATOM 2154 C CE2 . PHE A 1 278 ? -17.852 -6.105 3.734 1.00 94.10 ? 278 PHE A CE2 1 ATOM 2155 C CZ . PHE A 1 278 ? -17.641 -6.841 2.569 1.00 94.25 ? 278 PHE A CZ 1 ATOM 2156 N N . VAL A 1 279 ? -22.887 -1.456 2.727 1.00 91.57 ? 279 VAL A N 1 ATOM 2157 C CA . VAL A 1 279 ? -23.406 -0.098 2.589 1.00 91.57 ? 279 VAL A CA 1 ATOM 2158 C C . VAL A 1 279 ? -23.747 0.585 3.896 1.00 91.74 ? 279 VAL A C 1 ATOM 2159 O O . VAL A 1 279 ? -24.077 1.749 3.891 1.00 91.92 ? 279 VAL A O 1 ATOM 2160 C CB . VAL A 1 279 ? -24.624 -0.020 1.660 1.00 91.48 ? 279 VAL A CB 1 ATOM 2161 C CG1 . VAL A 1 279 ? -24.212 -0.280 0.241 1.00 91.48 ? 279 VAL A CG1 1 ATOM 2162 C CG2 . VAL A 1 279 ? -25.664 -1.006 2.075 1.00 91.79 ? 279 VAL A CG2 1 ATOM 2163 N N . VAL A 1 280 ? -23.677 -0.132 5.011 1.00 92.19 ? 280 VAL A N 1 ATOM 2164 C CA . VAL A 1 280 ? -23.847 0.492 6.327 1.00 92.60 ? 280 VAL A CA 1 ATOM 2165 C C . VAL A 1 280 ? -22.509 0.578 7.077 1.00 93.24 ? 280 VAL A C 1 ATOM 2166 O O . VAL A 1 280 ? -21.600 -0.211 6.826 1.00 93.25 ? 280 VAL A O 1 ATOM 2167 C CB . VAL A 1 280 ? -24.886 -0.251 7.210 1.00 92.41 ? 280 VAL A CB 1 ATOM 2168 C CG1 . VAL A 1 280 ? -26.112 -0.590 6.400 1.00 92.00 ? 280 VAL A CG1 1 ATOM 2169 C CG2 . VAL A 1 280 ? -24.271 -1.500 7.872 1.00 92.22 ? 280 VAL A CG2 1 ATOM 2170 N N . PRO A 1 281 ? -22.386 1.542 8.005 1.00 93.77 ? 281 PRO A N 1 ATOM 2171 C CA . PRO A 1 281 ? -21.178 1.713 8.816 1.00 93.77 ? 281 PRO A CA 1 ATOM 2172 C C . PRO A 1 281 ? -20.884 0.464 9.646 1.00 93.64 ? 281 PRO A C 1 ATOM 2173 O O . PRO A 1 281 ? -19.815 -0.108 9.534 1.00 93.83 ? 281 PRO A O 1 ATOM 2174 C CB . PRO A 1 281 ? -21.530 2.897 9.726 1.00 93.86 ? 281 PRO A CB 1 ATOM 2175 C CG . PRO A 1 281 ? -23.030 2.903 9.779 1.00 94.07 ? 281 PRO A CG 1 ATOM 2176 C CD . PRO A 1 281 ? -23.448 2.489 8.394 1.00 94.06 ? 281 PRO A CD 1 ATOM 2177 N N . TYR A 1 282 ? -21.821 0.043 10.478 1.00 93.41 ? 282 TYR A N 1 ATOM 2178 C CA . TYR A 1 282 ? -21.676 -1.232 11.158 1.00 93.07 ? 282 TYR A CA 1 ATOM 2179 C C . TYR A 1 282 ? -22.959 -1.990 10.918 1.00 92.35 ? 282 TYR A C 1 ATOM 2180 O O . TYR A 1 282 ? -23.968 -1.386 10.575 1.00 92.86 ? 282 TYR A O 1 ATOM 2181 C CB . TYR A 1 282 ? -21.429 -1.037 12.653 1.00 93.41 ? 282 TYR A CB 1 ATOM 2182 C CG . TYR A 1 282 ? -20.838 -2.144 13.126 0.0000 103.97 ? 282 TYR A CG 1 ATOM 2183 C CD1 . TYR A 1 282 ? -20.828 -2.218 14.533 0.0000 107.63 ? 282 TYR A CD1 1 ATOM 2184 C CD2 . TYR A 1 282 ? -20.279 -3.213 12.402 0.0000 107.27 ? 282 TYR A CD2 1 ATOM 2185 C CE1 . TYR A 1 282 ? -20.256 -3.311 15.211 0.0000 109.13 ? 282 TYR A CE1 1 ATOM 2186 C CE2 . TYR A 1 282 ? -19.697 -4.322 13.074 0.0000 109.10 ? 282 TYR A CE2 1 ATOM 2187 C CZ . TYR A 1 282 ? -19.697 -4.358 14.483 0.0000 110.10 ? 282 TYR A CZ 1 ATOM 2188 O OH . TYR A 1 282 ? -19.145 -5.423 15.178 0.0000 110.60 ? 282 TYR A OH 1 ATOM 2189 N N . GLY A 1 283 ? -22.932 -3.308 11.075 1.00 90.97 ? 283 GLY A N 1 ATOM 2190 C CA . GLY A 1 283 ? -24.133 -4.100 10.837 1.00 88.87 ? 283 GLY A CA 1 ATOM 2191 C C . GLY A 1 283 ? -24.449 -5.005 12.000 1.00 87.32 ? 283 GLY A C 1 ATOM 2192 O O . GLY A 1 283 ? -23.697 -5.052 12.960 1.00 87.52 ? 283 GLY A O 1 ATOM 2193 N N . THR A 1 284 ? -25.569 -5.717 11.923 1.00 85.62 ? 284 THR A N 1 ATOM 2194 C CA . THR A 1 284 ? -25.914 -6.720 12.928 1.00 83.82 ? 284 THR A CA 1 ATOM 2195 C C . THR A 1 284 ? -26.295 -7.987 12.220 1.00 82.39 ? 284 THR A C 1 ATOM 2196 O O . THR A 1 284 ? -26.563 -7.951 11.033 1.00 82.39 ? 284 THR A O 1 ATOM 2197 C CB . THR A 1 284 ? -27.119 -6.303 13.793 1.00 83.80 ? 284 THR A CB 1 ATOM 2198 O OG1 . THR A 1 284 ? -28.176 -5.830 12.949 1.00 83.71 ? 284 THR A OG1 1 ATOM 2199 C CG2 . THR A 1 284 ? -26.729 -5.213 14.748 1.00 83.81 ? 284 THR A CG2 1 ATOM 2200 N N . PRO A 1 285 ? -26.335 -9.105 12.951 1.00 81.12 ? 285 PRO A N 1 ATOM 2201 C CA . PRO A 1 285 ? -26.862 -10.364 12.453 1.00 80.24 ? 285 PRO A CA 1 ATOM 2202 C C . PRO A 1 285 ? -28.222 -10.163 11.808 1.00 79.31 ? 285 PRO A C 1 ATOM 2203 O O . PRO A 1 285 ? -28.653 -10.982 10.999 1.00 79.40 ? 285 PRO A O 1 ATOM 2204 C CB . PRO A 1 285 ? -27.034 -11.189 13.729 1.00 80.15 ? 285 PRO A CB 1 ATOM 2205 C CG . PRO A 1 285 ? -25.984 -10.697 14.619 1.00 80.60 ? 285 PRO A CG 1 ATOM 2206 C CD . PRO A 1 285 ? -25.827 -9.231 14.325 1.00 81.05 ? 285 PRO A CD 1 ATOM 2207 N N . LEU A 1 286 ? -28.876 -9.062 12.172 1.00 78.11 ? 286 LEU A N 1 ATOM 2208 C CA . LEU A 1 286 ? -30.232 -8.749 11.729 1.00 76.51 ? 286 LEU A CA 1 ATOM 2209 C C . LEU A 1 286 ? -30.310 -7.638 10.698 1.00 75.52 ? 286 LEU A C 1 ATOM 2210 O O . LEU A 1 286 ? -31.392 -7.245 10.310 1.00 75.30 ? 286 LEU A O 1 ATOM 2211 C CB . LEU A 1 286 ? -31.091 -8.370 12.935 1.00 76.31 ? 286 LEU A CB 1 ATOM 2212 C CG . LEU A 1 286 ? -31.646 -9.567 13.699 1.00 75.85 ? 286 LEU A CG 1 ATOM 2213 C CD1 . LEU A 1 286 ? -31.406 -9.461 15.171 1.00 76.00 ? 286 LEU A CD1 1 ATOM 2214 C CD2 . LEU A 1 286 ? -33.105 -9.707 13.429 1.00 75.70 ? 286 LEU A CD2 1 ATOM 2215 N N . SER A 1 287 ? -29.176 -7.130 10.248 1.00 74.51 ? 287 SER A N 1 ATOM 2216 C CA . SER A 1 287 ? -29.205 -5.993 9.346 1.00 73.78 ? 287 SER A CA 1 ATOM 2217 C C . SER A 1 287 ? -30.013 -6.315 8.094 1.00 72.95 ? 287 SER A C 1 ATOM 2218 O O . SER A 1 287 ? -29.710 -7.257 7.359 1.00 73.01 ? 287 SER A O 1 ATOM 2219 C CB . SER A 1 287 ? -27.793 -5.536 8.984 1.00 73.71 ? 287 SER A CB 1 ATOM 2220 O OG . SER A 1 287 ? -27.013 -5.405 10.155 1.00 74.37 ? 287 SER A OG 1 ATOM 2221 N N . VAL A 1 288 ? -31.060 -5.537 7.870 1.00 71.67 ? 288 VAL A N 1 ATOM 2222 C CA . VAL A 1 288 ? -31.802 -5.635 6.643 1.00 70.69 ? 288 VAL A CA 1 ATOM 2223 C C . VAL A 1 288 ? -31.369 -4.462 5.795 1.00 70.64 ? 288 VAL A C 1 ATOM 2224 O O . VAL A 1 288 ? -32.051 -3.458 5.773 1.00 70.90 ? 288 VAL A O 1 ATOM 2225 C CB . VAL A 1 288 ? -33.305 -5.523 6.893 1.00 70.32 ? 288 VAL A CB 1 ATOM 2226 C CG1 . VAL A 1 288 ? -34.010 -5.076 5.657 1.00 69.39 ? 288 VAL A CG1 1 ATOM 2227 C CG2 . VAL A 1 288 ? -33.852 -6.834 7.347 1.00 69.77 ? 288 VAL A CG2 1 ATOM 2228 N N . ASN A 1 289 ? -30.240 -4.593 5.097 1.00 70.37 ? 289 ASN A N 1 ATOM 2229 C CA . ASN A 1 289 ? -29.636 -3.477 4.366 1.00 70.11 ? 289 ASN A CA 1 ATOM 2230 C C . ASN A 1 289 ? -30.518 -2.821 3.321 1.00 69.73 ? 289 ASN A C 1 ATOM 2231 O O . ASN A 1 289 ? -30.562 -1.605 3.228 1.00 69.58 ? 289 ASN A O 1 ATOM 2232 C CB . ASN A 1 289 ? -28.331 -3.908 3.703 1.00 70.44 ? 289 ASN A CB 1 ATOM 2233 C CG . ASN A 1 289 ? -27.276 -4.360 4.711 1.00 71.80 ? 289 ASN A CG 1 ATOM 2234 O OD1 . ASN A 1 289 ? -26.760 -3.568 5.505 1.00 72.19 ? 289 ASN A OD1 1 ATOM 2235 N ND2 . ASN A 1 289 ? -26.937 -5.647 4.663 1.00 73.55 ? 289 ASN A ND2 1 ATOM 2236 N N . PHE A 1 290 ? -31.203 -3.615 2.514 1.00 69.58 ? 290 PHE A N 1 ATOM 2237 C CA . PHE A 1 290 ? -32.102 -3.043 1.519 1.00 69.37 ? 290 PHE A CA 1 ATOM 2238 C C . PHE A 1 290 ? -33.498 -3.552 1.703 1.00 68.96 ? 290 PHE A C 1 ATOM 2239 O O . PHE A 1 290 ? -33.795 -4.682 1.309 1.00 68.77 ? 290 PHE A O 1 ATOM 2240 C CB . PHE A 1 290 ? -31.641 -3.365 0.106 1.00 69.55 ? 290 PHE A CB 1 ATOM 2241 C CG . PHE A 1 290 ? -30.449 -2.577 -0.318 1.00 70.03 ? 290 PHE A CG 1 ATOM 2242 C CD1 . PHE A 1 290 ? -30.594 -1.394 -1.023 1.00 71.18 ? 290 PHE A CD1 1 ATOM 2243 C CD2 . PHE A 1 290 ? -29.185 -3.000 0.014 1.00 70.06 ? 290 PHE A CD2 1 ATOM 2244 C CE1 . PHE A 1 290 ? -29.489 -0.657 -1.410 1.00 70.48 ? 290 PHE A CE1 1 ATOM 2245 C CE2 . PHE A 1 290 ? -28.085 -2.275 -0.368 1.00 70.09 ? 290 PHE A CE2 1 ATOM 2246 C CZ . PHE A 1 290 ? -28.236 -1.100 -1.077 1.00 69.94 ? 290 PHE A CZ 1 ATOM 2247 N N . GLY A 1 291 ? -34.345 -2.707 2.294 1.00 68.43 ? 291 GLY A N 1 ATOM 2248 C CA . GLY A 1 291 ? -35.713 -3.078 2.614 1.00 67.77 ? 291 GLY A CA 1 ATOM 2249 C C . GLY A 1 291 ? -36.739 -2.096 2.130 1.00 67.18 ? 291 GLY A C 1 ATOM 2250 O O . GLY A 1 291 ? -36.428 -1.188 1.394 1.00 67.30 ? 291 GLY A O 1 ATOM 2251 N N . PRO A 1 292 ? -37.985 -2.293 2.541 1.00 66.96 ? 292 PRO A N 1 ATOM 2252 C CA . PRO A 1 292 ? -39.110 -1.432 2.212 1.00 66.61 ? 292 PRO A CA 1 ATOM 2253 C C . PRO A 1 292 ? -38.907 -0.015 2.724 1.00 66.28 ? 292 PRO A C 1 ATOM 2254 O O . PRO A 1 292 ? -38.423 0.183 3.850 1.00 66.07 ? 292 PRO A O 1 ATOM 2255 C CB . PRO A 1 292 ? -40.283 -2.077 2.959 1.00 66.54 ? 292 PRO A CB 1 ATOM 2256 C CG . PRO A 1 292 ? -39.887 -3.473 3.178 1.00 67.16 ? 292 PRO A CG 1 ATOM 2257 C CD . PRO A 1 292 ? -38.391 -3.460 3.335 1.00 67.33 ? 292 PRO A CD 1 ATOM 2258 N N . THR A 1 293 ? -39.280 0.965 1.900 1.00 65.87 ? 293 THR A N 1 ATOM 2259 C CA . THR A 1 293 ? -39.201 2.367 2.301 1.00 65.39 ? 293 THR A CA 1 ATOM 2260 C C . THR A 1 293 ? -40.484 3.114 2.008 1.00 65.00 ? 293 THR A C 1 ATOM 2261 O O . THR A 1 293 ? -41.369 2.613 1.331 1.00 64.48 ? 293 THR A O 1 ATOM 2262 C CB . THR A 1 293 ? -38.059 3.097 1.618 1.00 65.13 ? 293 THR A CB 1 ATOM 2263 O OG1 . THR A 1 293 ? -38.046 2.727 0.243 1.00 65.27 ? 293 THR A OG1 1 ATOM 2264 C CG2 . THR A 1 293 ? -36.748 2.718 2.253 1.00 64.96 ? 293 THR A CG2 1 ATOM 2265 N N . VAL A 1 294 ? -40.585 4.315 2.549 1.00 64.92 ? 294 VAL A N 1 ATOM 2266 C CA . VAL A 1 294 ? -41.763 5.101 2.315 1.00 65.09 ? 294 VAL A CA 1 ATOM 2267 C C . VAL A 1 294 ? -41.620 5.715 0.944 1.00 65.28 ? 294 VAL A C 1 ATOM 2268 O O . VAL A 1 294 ? -40.971 6.734 0.768 1.00 65.46 ? 294 VAL A O 1 ATOM 2269 C CB . VAL A 1 294 ? -41.941 6.170 3.367 1.00 64.94 ? 294 VAL A CB 1 ATOM 2270 C CG1 . VAL A 1 294 ? -43.299 6.790 3.227 1.00 64.35 ? 294 VAL A CG1 1 ATOM 2271 C CG2 . VAL A 1 294 ? -41.793 5.549 4.733 1.00 65.07 ? 294 VAL A CG2 1 ATOM 2272 N N . ASP A 1 295 ? -42.218 5.064 -0.036 1.00 65.26 ? 295 ASP A N 1 ATOM 2273 C CA . ASP A 1 295 ? -41.968 5.410 -1.401 1.00 65.36 ? 295 ASP A CA 1 ATOM 2274 C C . ASP A 1 295 ? -43.044 6.357 -1.879 1.00 65.43 ? 295 ASP A C 1 ATOM 2275 O O . ASP A 1 295 ? -42.994 6.856 -2.992 1.00 65.47 ? 295 ASP A O 1 ATOM 2276 C CB . ASP A 1 295 ? -41.914 4.139 -2.260 1.00 65.47 ? 295 ASP A CB 1 ATOM 2277 C CG . ASP A 1 295 ? -43.265 3.476 -2.418 1.00 65.83 ? 295 ASP A CG 1 ATOM 2278 O OD1 . ASP A 1 295 ? -44.116 3.686 -1.548 1.00 66.75 ? 295 ASP A OD1 1 ATOM 2279 O OD2 . ASP A 1 295 ? -43.481 2.757 -3.417 1.00 67.05 ? 295 ASP A OD2 1 ATOM 2280 N N . GLY A 1 296 ? -44.028 6.614 -1.038 1.00 65.48 ? 296 GLY A N 1 ATOM 2281 C CA . GLY A 1 296 ? -45.146 7.430 -1.475 1.00 65.61 ? 296 GLY A CA 1 ATOM 2282 C C . GLY A 1 296 ? -45.925 6.794 -2.607 1.00 65.57 ? 296 GLY A C 1 ATOM 2283 O O . GLY A 1 296 ? -46.799 7.427 -3.190 1.00 65.60 ? 296 GLY A O 1 ATOM 2284 N N . ASP A 1 297 ? -45.592 5.545 -2.920 1.00 65.73 ? 297 ASP A N 1 ATOM 2285 C CA . ASP A 1 297 ? -46.384 4.744 -3.854 1.00 65.96 ? 297 ASP A CA 1 ATOM 2286 C C . ASP A 1 297 ? -47.045 3.572 -3.127 1.00 65.63 ? 297 ASP A C 1 ATOM 2287 O O . ASP A 1 297 ? -48.197 3.644 -2.726 1.00 65.61 ? 297 ASP A O 1 ATOM 2288 C CB . ASP A 1 297 ? -45.534 4.237 -5.024 1.00 66.16 ? 297 ASP A CB 1 ATOM 2289 C CG . ASP A 1 297 ? -46.376 3.656 -6.144 1.00 67.37 ? 297 ASP A CG 1 ATOM 2290 O OD1 . ASP A 1 297 ? -47.616 3.631 -6.012 1.00 68.17 ? 297 ASP A OD1 1 ATOM 2291 O OD2 . ASP A 1 297 ? -45.805 3.215 -7.161 1.00 69.44 ? 297 ASP A OD2 1 ATOM 2292 N N . PHE A 1 298 ? -46.307 2.492 -2.938 1.00 65.30 ? 298 PHE A N 1 ATOM 2293 C CA . PHE A 1 298 ? -46.827 1.373 -2.177 1.00 65.00 ? 298 PHE A CA 1 ATOM 2294 C C . PHE A 1 298 ? -47.141 1.768 -0.714 1.00 65.03 ? 298 PHE A C 1 ATOM 2295 O O . PHE A 1 298 ? -48.177 1.407 -0.154 1.00 64.72 ? 298 PHE A O 1 ATOM 2296 C CB . PHE A 1 298 ? -45.816 0.236 -2.223 1.00 64.71 ? 298 PHE A CB 1 ATOM 2297 C CG . PHE A 1 298 ? -46.336 -1.047 -1.679 1.00 64.01 ? 298 PHE A CG 1 ATOM 2298 C CD1 . PHE A 1 298 ? -46.241 -1.335 -0.330 1.00 62.68 ? 298 PHE A CD1 1 ATOM 2299 C CD2 . PHE A 1 298 ? -46.924 -1.964 -2.516 1.00 63.74 ? 298 PHE A CD2 1 ATOM 2300 C CE1 . PHE A 1 298 ? -46.708 -2.513 0.172 1.00 62.69 ? 298 PHE A CE1 1 ATOM 2301 C CE2 . PHE A 1 298 ? -47.406 -3.147 -2.023 1.00 64.13 ? 298 PHE A CE2 1 ATOM 2302 C CZ . PHE A 1 298 ? -47.304 -3.421 -0.669 1.00 64.00 ? 298 PHE A CZ 1 ATOM 2303 N N . LEU A 1 299 ? -46.206 2.475 -0.101 1.00 65.07 ? 299 LEU A N 1 ATOM 2304 C CA . LEU A 1 299 ? -46.414 3.082 1.180 1.00 65.49 ? 299 LEU A CA 1 ATOM 2305 C C . LEU A 1 299 ? -46.638 4.540 0.883 1.00 66.12 ? 299 LEU A C 1 ATOM 2306 O O . LEU A 1 299 ? -45.835 5.148 0.203 1.00 66.30 ? 299 LEU A O 1 ATOM 2307 C CB . LEU A 1 299 ? -45.182 2.930 2.066 1.00 65.10 ? 299 LEU A CB 1 ATOM 2308 C CG . LEU A 1 299 ? -45.203 1.770 3.048 1.00 65.27 ? 299 LEU A CG 1 ATOM 2309 C CD1 . LEU A 1 299 ? -44.403 2.094 4.298 1.00 66.85 ? 299 LEU A CD1 1 ATOM 2310 C CD2 . LEU A 1 299 ? -46.622 1.479 3.442 1.00 66.12 ? 299 LEU A CD2 1 ATOM 2311 N N . THR A 1 300 ? -47.727 5.111 1.390 1.00 66.98 ? 300 THR A N 1 ATOM 2312 C CA . THR A 1 300 ? -48.053 6.510 1.101 1.00 67.37 ? 300 THR A CA 1 ATOM 2313 C C . THR A 1 300 ? -47.761 7.464 2.229 1.00 67.53 ? 300 THR A C 1 ATOM 2314 O O . THR A 1 300 ? -48.157 8.606 2.154 1.00 68.02 ? 300 THR A O 1 ATOM 2315 C CB . THR A 1 300 ? -49.530 6.688 0.722 1.00 67.22 ? 300 THR A CB 1 ATOM 2316 O OG1 . THR A 1 300 ? -50.301 5.688 1.387 1.00 67.67 ? 300 THR A OG1 1 ATOM 2317 C CG2 . THR A 1 300 ? -49.723 6.541 -0.792 1.00 67.40 ? 300 THR A CG2 1 ATOM 2318 N N . ASP A 1 301 ? -47.075 7.005 3.265 1.00 67.86 ? 301 ASP A N 1 ATOM 2319 C CA . ASP A 1 301 ? -46.804 7.830 4.433 1.00 68.41 ? 301 ASP A CA 1 ATOM 2320 C C . ASP A 1 301 ? -46.149 6.875 5.405 1.00 68.41 ? 301 ASP A C 1 ATOM 2321 O O . ASP A 1 301 ? -46.285 5.676 5.251 1.00 68.82 ? 301 ASP A O 1 ATOM 2322 C CB . ASP A 1 301 ? -48.117 8.387 4.989 1.00 68.83 ? 301 ASP A CB 1 ATOM 2323 C CG . ASP A 1 301 ? -47.928 9.317 6.180 1.00 70.47 ? 301 ASP A CG 1 ATOM 2324 O OD1 . ASP A 1 301 ? -48.944 9.868 6.656 1.00 71.06 ? 301 ASP A OD1 1 ATOM 2325 O OD2 . ASP A 1 301 ? -46.781 9.496 6.653 1.00 72.79 ? 301 ASP A OD2 1 ATOM 2326 N N . MET A 1 302 ? -45.411 7.379 6.381 1.00 68.37 ? 302 MET A N 1 ATOM 2327 C CA . MET A 1 302 ? -44.790 6.490 7.321 1.00 68.73 ? 302 MET A CA 1 ATOM 2328 C C . MET A 1 302 ? -45.858 5.589 7.905 1.00 68.94 ? 302 MET A C 1 ATOM 2329 O O . MET A 1 302 ? -46.937 6.042 8.289 1.00 68.94 ? 302 MET A O 1 ATOM 2330 C CB . MET A 1 302 ? -44.106 7.289 8.393 1.00 68.96 ? 302 MET A CB 1 ATOM 2331 C CG . MET A 1 302 ? -43.211 8.327 7.803 1.00 70.67 ? 302 MET A CG 1 ATOM 2332 S SD . MET A 1 302 ? -42.147 9.053 9.057 1.00 75.92 ? 302 MET A SD 1 ATOM 2333 C CE . MET A 1 302 ? -41.653 7.600 10.036 1.00 74.63 ? 302 MET A CE 1 ATOM 2334 N N . PRO A 1 303 ? -45.572 4.291 7.952 1.00 69.06 ? 303 PRO A N 1 ATOM 2335 C CA . PRO A 1 303 ? -46.593 3.331 8.297 1.00 68.90 ? 303 PRO A CA 1 ATOM 2336 C C . PRO A 1 303 ? -46.986 3.346 9.773 1.00 68.73 ? 303 PRO A C 1 ATOM 2337 O O . PRO A 1 303 ? -48.119 3.004 10.092 1.00 69.07 ? 303 PRO A O 1 ATOM 2338 C CB . PRO A 1 303 ? -45.964 2.002 7.904 1.00 68.72 ? 303 PRO A CB 1 ATOM 2339 C CG . PRO A 1 303 ? -44.543 2.228 7.958 1.00 69.14 ? 303 PRO A CG 1 ATOM 2340 C CD . PRO A 1 303 ? -44.274 3.660 7.692 1.00 69.11 ? 303 PRO A CD 1 ATOM 2341 N N . ASP A 1 304 ? -46.100 3.751 10.672 1.00 68.17 ? 304 ASP A N 1 ATOM 2342 C CA . ASP A 1 304 ? -46.522 3.820 12.065 1.00 67.83 ? 304 ASP A CA 1 ATOM 2343 C C . ASP A 1 304 ? -47.633 4.841 12.213 1.00 66.62 ? 304 ASP A C 1 ATOM 2344 O O . ASP A 1 304 ? -48.510 4.689 13.040 1.00 66.74 ? 304 ASP A O 1 ATOM 2345 C CB . ASP A 1 304 ? -45.372 4.162 12.999 1.00 68.56 ? 304 ASP A CB 1 ATOM 2346 C CG . ASP A 1 304 ? -44.540 5.332 12.492 1.00 71.80 ? 304 ASP A CG 1 ATOM 2347 O OD1 . ASP A 1 304 ? -44.294 5.387 11.247 1.00 74.03 ? 304 ASP A OD1 1 ATOM 2348 O OD2 . ASP A 1 304 ? -44.157 6.193 13.334 1.00 74.06 ? 304 ASP A OD2 1 ATOM 2349 N N . ILE A 1 305 ? -47.595 5.891 11.411 1.00 65.19 ? 305 ILE A N 1 ATOM 2350 C CA . ILE A 1 305 ? -48.647 6.875 11.465 1.00 63.74 ? 305 ILE A CA 1 ATOM 2351 C C . ILE A 1 305 ? -49.942 6.278 10.941 1.00 62.96 ? 305 ILE A C 1 ATOM 2352 O O . ILE A 1 305 ? -50.974 6.408 11.581 1.00 62.81 ? 305 ILE A O 1 ATOM 2353 C CB . ILE A 1 305 ? -48.275 8.138 10.699 1.00 63.78 ? 305 ILE A CB 1 ATOM 2354 C CG1 . ILE A 1 305 ? -47.060 8.814 11.334 1.00 62.91 ? 305 ILE A CG1 1 ATOM 2355 C CG2 . ILE A 1 305 ? -49.423 9.112 10.707 1.00 64.45 ? 305 ILE A CG2 1 ATOM 2356 C CD1 . ILE A 1 305 ? -46.510 9.914 10.496 1.00 60.69 ? 305 ILE A CD1 1 ATOM 2357 N N . LEU A 1 306 ? -49.899 5.614 9.788 1.00 62.27 ? 306 LEU A N 1 ATOM 2358 C CA . LEU A 1 306 ? -51.087 4.929 9.236 1.00 61.46 ? 306 LEU A CA 1 ATOM 2359 C C . LEU A 1 306 ? -51.705 3.905 10.187 1.00 61.07 ? 306 LEU A C 1 ATOM 2360 O O . LEU A 1 306 ? -52.922 3.741 10.223 1.00 60.68 ? 306 LEU A O 1 ATOM 2361 C CB . LEU A 1 306 ? -50.713 4.197 7.969 1.00 61.33 ? 306 LEU A CB 1 ATOM 2362 C CG . LEU A 1 306 ? -50.104 5.118 6.956 1.00 61.55 ? 306 LEU A CG 1 ATOM 2363 C CD1 . LEU A 1 306 ? -49.279 4.325 5.997 1.00 62.77 ? 306 LEU A CD1 1 ATOM 2364 C CD2 . LEU A 1 306 ? -51.223 5.792 6.246 1.00 62.52 ? 306 LEU A CD2 1 ATOM 2365 N N . LEU A 1 307 ? -50.854 3.193 10.921 1.00 60.39 ? 307 LEU A N 1 ATOM 2366 C CA . LEU A 1 307 ? -51.316 2.211 11.872 1.00 59.85 ? 307 LEU A CA 1 ATOM 2367 C C . LEU A 1 307 ? -51.939 2.953 13.021 1.00 59.81 ? 307 LEU A C 1 ATOM 2368 O O . LEU A 1 307 ? -53.027 2.627 13.476 1.00 59.73 ? 307 LEU A O 1 ATOM 2369 C CB . LEU A 1 307 ? -50.151 1.355 12.369 1.00 59.56 ? 307 LEU A CB 1 ATOM 2370 C CG . LEU A 1 307 ? -50.447 0.460 13.579 1.00 58.58 ? 307 LEU A CG 1 ATOM 2371 C CD1 . LEU A 1 307 ? -51.507 -0.560 13.238 1.00 57.39 ? 307 LEU A CD1 1 ATOM 2372 C CD2 . LEU A 1 307 ? -49.207 -0.213 14.104 1.00 56.67 ? 307 LEU A CD2 1 ATOM 2373 N N . GLU A 1 308 ? -51.237 3.973 13.476 1.00 59.83 ? 308 GLU A N 1 ATOM 2374 C CA . GLU A 1 308 ? -51.665 4.745 14.620 1.00 60.15 ? 308 GLU A CA 1 ATOM 2375 C C . GLU A 1 308 ? -53.043 5.323 14.422 1.00 59.89 ? 308 GLU A C 1 ATOM 2376 O O . GLU A 1 308 ? -53.827 5.350 15.347 1.00 59.96 ? 308 GLU A O 1 ATOM 2377 C CB . GLU A 1 308 ? -50.699 5.890 14.865 1.00 60.63 ? 308 GLU A CB 1 ATOM 2378 C CG . GLU A 1 308 ? -51.057 6.702 16.041 1.00 62.81 ? 308 GLU A CG 1 ATOM 2379 C CD . GLU A 1 308 ? -51.274 5.819 17.218 1.00 66.85 ? 308 GLU A CD 1 ATOM 2380 O OE1 . GLU A 1 308 ? -51.958 6.252 18.166 1.00 68.64 ? 308 GLU A OE1 1 ATOM 2381 O OE2 . GLU A 1 308 ? -50.785 4.667 17.165 1.00 68.13 ? 308 GLU A OE2 1 ATOM 2382 N N . LEU A 1 309 ? -53.332 5.785 13.207 1.00 59.69 ? 309 LEU A N 1 ATOM 2383 C CA . LEU A 1 309 ? -54.549 6.530 12.928 1.00 59.29 ? 309 LEU A CA 1 ATOM 2384 C C . LEU A 1 309 ? -55.560 5.723 12.132 1.00 59.78 ? 309 LEU A C 1 ATOM 2385 O O . LEU A 1 309 ? -56.362 6.284 11.390 1.00 59.81 ? 309 LEU A O 1 ATOM 2386 C CB . LEU A 1 309 ? -54.197 7.797 12.173 1.00 58.85 ? 309 LEU A CB 1 ATOM 2387 C CG . LEU A 1 309 ? -53.138 8.637 12.870 1.00 58.35 ? 309 LEU A CG 1 ATOM 2388 C CD1 . LEU A 1 309 ? -52.764 9.825 12.047 1.00 58.47 ? 309 LEU A CD1 1 ATOM 2389 C CD2 . LEU A 1 309 ? -53.658 9.097 14.206 1.00 58.05 ? 309 LEU A CD2 1 ATOM 2390 N N . GLY A 1 310 ? -55.518 4.403 12.279 1.00 60.37 ? 310 GLY A N 1 ATOM 2391 C CA . GLY A 1 310 ? -56.472 3.519 11.607 1.00 61.15 ? 310 GLY A CA 1 ATOM 2392 C C . GLY A 1 310 ? -56.540 3.594 10.079 1.00 61.70 ? 310 GLY A C 1 ATOM 2393 O O . GLY A 1 310 ? -57.614 3.512 9.506 1.00 61.93 ? 310 GLY A O 1 ATOM 2394 N N . GLN A 1 311 ? -55.409 3.721 9.402 1.00 61.73 ? 311 GLN A N 1 ATOM 2395 C CA . GLN A 1 311 ? -55.451 3.827 7.961 1.00 62.06 ? 311 GLN A CA 1 ATOM 2396 C C . GLN A 1 311 ? -55.061 2.542 7.249 1.00 61.87 ? 311 GLN A C 1 ATOM 2397 O O . GLN A 1 311 ? -54.042 2.480 6.555 1.00 61.80 ? 311 GLN A O 1 ATOM 2398 C CB . GLN A 1 311 ? -54.548 4.953 7.537 1.00 62.47 ? 311 GLN A CB 1 ATOM 2399 C CG . GLN A 1 311 ? -55.092 6.248 8.006 1.00 65.09 ? 311 GLN A CG 1 ATOM 2400 C CD . GLN A 1 311 ? -56.436 6.560 7.362 1.00 68.09 ? 311 GLN A CD 1 ATOM 2401 O OE1 . GLN A 1 311 ? -57.449 6.720 8.063 1.00 67.91 ? 311 GLN A OE1 1 ATOM 2402 N NE2 . GLN A 1 311 ? -56.452 6.645 6.013 1.00 68.00 ? 311 GLN A NE2 1 ATOM 2403 N N . PHE A 1 312 ? -55.879 1.511 7.406 1.00 61.48 ? 312 PHE A N 1 ATOM 2404 C CA . PHE A 1 312 ? -55.534 0.225 6.843 1.00 61.07 ? 312 PHE A CA 1 ATOM 2405 C C . PHE A 1 312 ? -56.741 -0.653 6.590 1.00 60.83 ? 312 PHE A C 1 ATOM 2406 O O . PHE A 1 312 ? -57.823 -0.407 7.120 1.00 60.93 ? 312 PHE A O 1 ATOM 2407 C CB . PHE A 1 312 ? -54.605 -0.491 7.801 1.00 60.94 ? 312 PHE A CB 1 ATOM 2408 C CG . PHE A 1 312 ? -55.070 -0.469 9.218 1.00 60.49 ? 312 PHE A CG 1 ATOM 2409 C CD1 . PHE A 1 312 ? -55.974 -1.400 9.675 1.00 60.27 ? 312 PHE A CD1 1 ATOM 2410 C CD2 . PHE A 1 312 ? -54.577 0.460 10.104 1.00 60.73 ? 312 PHE A CD2 1 ATOM 2411 C CE1 . PHE A 1 312 ? -56.388 -1.399 11.000 1.00 59.91 ? 312 PHE A CE1 1 ATOM 2412 C CE2 . PHE A 1 312 ? -54.977 0.459 11.431 1.00 60.48 ? 312 PHE A CE2 1 ATOM 2413 C CZ . PHE A 1 312 ? -55.890 -0.469 11.876 1.00 59.82 ? 312 PHE A CZ 1 ATOM 2414 N N . LYS A 1 313 ? -56.553 -1.693 5.788 1.00 60.37 ? 313 LYS A N 1 ATOM 2415 C CA . LYS A 1 313 ? -57.652 -2.607 5.510 1.00 59.81 ? 313 LYS A CA 1 ATOM 2416 C C . LYS A 1 313 ? -58.245 -3.014 6.825 1.00 59.46 ? 313 LYS A C 1 ATOM 2417 O O . LYS A 1 313 ? -57.523 -3.312 7.774 1.00 59.30 ? 313 LYS A O 1 ATOM 2418 C CB . LYS A 1 313 ? -57.178 -3.847 4.761 1.00 59.77 ? 313 LYS A CB 1 ATOM 2419 C CG . LYS A 1 313 ? -58.255 -4.858 4.509 1.00 59.37 ? 313 LYS A CG 1 ATOM 2420 C CD . LYS A 1 313 ? -57.906 -5.758 3.340 1.00 60.28 ? 313 LYS A CD 1 ATOM 2421 C CE . LYS A 1 313 ? -59.149 -6.160 2.588 1.00 61.02 ? 313 LYS A CE 1 ATOM 2422 N NZ . LYS A 1 313 ? -59.089 -7.585 2.264 1.00 61.61 ? 313 LYS A NZ 1 ATOM 2423 N N . LYS A 1 314 ? -59.566 -3.008 6.882 1.00 59.07 ? 314 LYS A N 1 ATOM 2424 C CA . LYS A 1 314 ? -60.268 -3.496 8.047 1.00 59.05 ? 314 LYS A CA 1 ATOM 2425 C C . LYS A 1 314 ? -60.670 -4.956 7.832 1.00 58.92 ? 314 LYS A C 1 ATOM 2426 O O . LYS A 1 314 ? -61.395 -5.270 6.897 1.00 58.98 ? 314 LYS A O 1 ATOM 2427 C CB . LYS A 1 314 ? -61.482 -2.620 8.286 1.00 59.03 ? 314 LYS A CB 1 ATOM 2428 C CG . LYS A 1 314 ? -61.115 -1.143 8.466 1.00 60.14 ? 314 LYS A CG 1 ATOM 2429 C CD . LYS A 1 314 ? -60.203 -0.976 9.677 1.00 61.30 ? 314 LYS A CD 1 ATOM 2430 C CE . LYS A 1 314 ? -60.127 0.473 10.145 1.00 61.63 ? 314 LYS A CE 1 ATOM 2431 N NZ . LYS A 1 314 ? -59.707 1.380 9.061 1.00 61.14 ? 314 LYS A NZ 1 ATOM 2432 N N . THR A 1 315 ? -60.177 -5.858 8.672 1.00 58.70 ? 315 THR A N 1 ATOM 2433 C CA . THR A 1 315 ? -60.446 -7.269 8.470 1.00 58.83 ? 315 THR A CA 1 ATOM 2434 C C . THR A 1 315 ? -59.831 -8.018 9.608 1.00 58.46 ? 315 THR A C 1 ATOM 2435 O O . THR A 1 315 ? -59.155 -7.412 10.416 1.00 58.94 ? 315 THR A O 1 ATOM 2436 C CB . THR A 1 315 ? -59.822 -7.768 7.173 1.00 59.12 ? 315 THR A CB 1 ATOM 2437 O OG1 . THR A 1 315 ? -60.125 -9.154 7.016 1.00 60.60 ? 315 THR A OG1 1 ATOM 2438 C CG2 . THR A 1 315 ? -58.307 -7.608 7.213 1.00 59.73 ? 315 THR A CG2 1 ATOM 2439 N N . GLN A 1 316 ? -60.054 -9.325 9.701 1.00 58.31 ? 316 GLN A N 1 ATOM 2440 C CA . GLN A 1 316 ? -59.489 -10.077 10.836 1.00 58.14 ? 316 GLN A CA 1 ATOM 2441 C C . GLN A 1 316 ? -58.024 -10.369 10.572 1.00 58.12 ? 316 GLN A C 1 ATOM 2442 O O . GLN A 1 316 ? -57.575 -10.435 9.428 1.00 58.31 ? 316 GLN A O 1 ATOM 2443 C CB . GLN A 1 316 ? -60.237 -11.389 11.120 1.00 57.78 ? 316 GLN A CB 1 ATOM 2444 C CG . GLN A 1 316 ? -61.734 -11.310 10.989 1.00 57.93 ? 316 GLN A CG 1 ATOM 2445 C CD . GLN A 1 316 ? -62.158 -11.044 9.568 1.00 58.12 ? 316 GLN A CD 1 ATOM 2446 O OE1 . GLN A 1 316 ? -61.506 -11.498 8.634 1.00 59.63 ? 316 GLN A OE1 1 ATOM 2447 N NE2 . GLN A 1 316 ? -63.236 -10.287 9.391 1.00 57.28 ? 316 GLN A NE2 1 ATOM 2448 N N . ILE A 1 317 ? -57.275 -10.533 11.645 1.00 57.86 ? 317 ILE A N 1 ATOM 2449 C CA . ILE A 1 317 ? -55.886 -10.899 11.528 1.00 57.59 ? 317 ILE A CA 1 ATOM 2450 C C . ILE A 1 317 ? -55.529 -11.948 12.591 1.00 57.48 ? 317 ILE A C 1 ATOM 2451 O O . ILE A 1 317 ? -56.121 -11.991 13.684 1.00 57.24 ? 317 ILE A O 1 ATOM 2452 C CB . ILE A 1 317 ? -54.985 -9.683 11.684 1.00 57.62 ? 317 ILE A CB 1 ATOM 2453 C CG1 . ILE A 1 317 ? -55.332 -8.961 12.984 1.00 58.46 ? 317 ILE A CG1 1 ATOM 2454 C CG2 . ILE A 1 317 ? -55.142 -8.767 10.514 1.00 56.36 ? 317 ILE A CG2 1 ATOM 2455 C CD1 . ILE A 1 317 ? -54.265 -8.019 13.477 1.00 59.39 ? 317 ILE A CD1 1 ATOM 2456 N N . LEU A 1 318 ? -54.581 -12.811 12.233 1.00 57.11 ? 318 LEU A N 1 ATOM 2457 C CA . LEU A 1 318 ? -54.066 -13.822 13.124 1.00 56.62 ? 318 LEU A CA 1 ATOM 2458 C C . LEU A 1 318 ? -52.599 -13.492 13.223 1.00 56.30 ? 318 LEU A C 1 ATOM 2459 O O . LEU A 1 318 ? -51.938 -13.299 12.203 1.00 56.28 ? 318 LEU A O 1 ATOM 2460 C CB . LEU A 1 318 ? -54.290 -15.204 12.525 1.00 56.65 ? 318 LEU A CB 1 ATOM 2461 C CG . LEU A 1 318 ? -54.108 -16.455 13.385 1.00 57.01 ? 318 LEU A CG 1 ATOM 2462 C CD1 . LEU A 1 318 ? -54.885 -17.583 12.782 1.00 58.13 ? 318 LEU A CD1 1 ATOM 2463 C CD2 . LEU A 1 318 ? -52.668 -16.875 13.495 1.00 57.80 ? 318 LEU A CD2 1 ATOM 2464 N N . VAL A 1 319 ? -52.098 -13.386 14.446 1.00 55.74 ? 319 VAL A N 1 ATOM 2465 C CA . VAL A 1 319 ? -50.727 -12.948 14.666 1.00 55.68 ? 319 VAL A CA 1 ATOM 2466 C C . VAL A 1 319 ? -50.122 -13.774 15.788 1.00 55.99 ? 319 VAL A C 1 ATOM 2467 O O . VAL A 1 319 ? -50.845 -14.248 16.661 1.00 56.57 ? 319 VAL A O 1 ATOM 2468 C CB . VAL A 1 319 ? -50.678 -11.480 15.073 1.00 55.41 ? 319 VAL A CB 1 ATOM 2469 C CG1 . VAL A 1 319 ? -49.265 -11.027 15.205 1.00 55.56 ? 319 VAL A CG1 1 ATOM 2470 C CG2 . VAL A 1 319 ? -51.380 -10.619 14.051 1.00 56.20 ? 319 VAL A CG2 1 ATOM 2471 N N . GLY A 1 320 ? -48.803 -13.961 15.777 1.00 55.87 ? 320 GLY A N 1 ATOM 2472 C CA . GLY A 1 320 ? -48.157 -14.769 16.813 1.00 55.36 ? 320 GLY A CA 1 ATOM 2473 C C . GLY A 1 320 ? -46.651 -14.853 16.676 1.00 55.14 ? 320 GLY A C 1 ATOM 2474 O O . GLY A 1 320 ? -46.084 -14.451 15.669 1.00 55.29 ? 320 GLY A O 1 ATOM 2475 N N . VAL A 1 321 ? -46.002 -15.393 17.692 1.00 54.84 ? 321 VAL A N 1 ATOM 2476 C CA . VAL A 1 321 ? -44.561 -15.464 17.712 1.00 54.92 ? 321 VAL A CA 1 ATOM 2477 C C . VAL A 1 321 ? -44.146 -16.793 18.326 1.00 55.48 ? 321 VAL A C 1 ATOM 2478 O O . VAL A 1 321 ? -44.995 -17.575 18.738 1.00 55.77 ? 321 VAL A O 1 ATOM 2479 C CB . VAL A 1 321 ? -43.972 -14.308 18.542 1.00 54.59 ? 321 VAL A CB 1 ATOM 2480 C CG1 . VAL A 1 321 ? -44.435 -12.975 18.011 1.00 54.09 ? 321 VAL A CG1 1 ATOM 2481 C CG2 . VAL A 1 321 ? -44.397 -14.425 19.953 1.00 54.91 ? 321 VAL A CG2 1 ATOM 2482 N N . ASN A 1 322 ? -42.847 -17.056 18.378 1.00 56.00 ? 322 ASN A N 1 ATOM 2483 C CA . ASN A 1 322 ? -42.333 -18.265 18.990 1.00 56.50 ? 322 ASN A CA 1 ATOM 2484 C C . ASN A 1 322 ? -41.667 -17.940 20.300 1.00 57.00 ? 322 ASN A C 1 ATOM 2485 O O . ASN A 1 322 ? -41.185 -16.826 20.495 1.00 57.35 ? 322 ASN A O 1 ATOM 2486 C CB . ASN A 1 322 ? -41.319 -18.928 18.078 1.00 56.60 ? 322 ASN A CB 1 ATOM 2487 C CG . ASN A 1 322 ? -41.922 -19.363 16.777 1.00 57.32 ? 322 ASN A CG 1 ATOM 2488 O OD1 . ASN A 1 322 ? -41.228 -19.815 15.867 1.00 58.34 ? 322 ASN A OD1 1 ATOM 2489 N ND2 . ASN A 1 322 ? -43.228 -19.224 16.674 1.00 57.92 ? 322 ASN A ND2 1 ATOM 2490 N N . LYS A 1 323 ? -41.615 -18.929 21.187 1.00 57.45 ? 323 LYS A N 1 ATOM 2491 C CA . LYS A 1 323 ? -41.069 -18.750 22.528 1.00 57.87 ? 323 LYS A CA 1 ATOM 2492 C C . LYS A 1 323 ? -39.676 -18.156 22.566 1.00 57.99 ? 323 LYS A C 1 ATOM 2493 O O . LYS A 1 323 ? -39.388 -17.387 23.456 1.00 58.15 ? 323 LYS A O 1 ATOM 2494 C CB . LYS A 1 323 ? -41.111 -20.061 23.299 1.00 57.84 ? 323 LYS A CB 1 ATOM 2495 C CG . LYS A 1 323 ? -40.601 -19.987 24.708 1.00 59.10 ? 323 LYS A CG 1 ATOM 2496 C CD . LYS A 1 323 ? -41.562 -20.743 25.616 1.00 61.74 ? 323 LYS A CD 1 ATOM 2497 C CE . LYS A 1 323 ? -40.844 -21.591 26.661 1.00 63.45 ? 323 LYS A CE 1 ATOM 2498 N NZ . LYS A 1 323 ? -39.405 -21.803 26.333 1.00 64.29 ? 323 LYS A NZ 1 ATOM 2499 N N . ASP A 1 324 ? -38.833 -18.475 21.588 1.00 58.52 ? 324 ASP A N 1 ATOM 2500 C CA . ASP A 1 324 ? -37.430 -18.043 21.603 1.00 58.93 ? 324 ASP A CA 1 ATOM 2501 C C . ASP A 1 324 ? -36.940 -17.389 20.326 1.00 59.20 ? 324 ASP A C 1 ATOM 2502 O O . ASP A 1 324 ? -35.911 -17.757 19.799 1.00 59.35 ? 324 ASP A O 1 ATOM 2503 C CB . ASP A 1 324 ? -36.545 -19.231 21.911 1.00 58.74 ? 324 ASP A CB 1 ATOM 2504 C CG . ASP A 1 324 ? -36.807 -19.785 23.280 1.00 59.40 ? 324 ASP A CG 1 ATOM 2505 O OD1 . ASP A 1 324 ? -36.650 -19.009 24.238 1.00 60.77 ? 324 ASP A OD1 1 ATOM 2506 O OD2 . ASP A 1 324 ? -37.170 -20.979 23.408 1.00 59.31 ? 324 ASP A OD2 1 ATOM 2507 N N . GLU A 1 325 ? -37.667 -16.404 19.840 1.00 59.73 ? 325 GLU A N 1 ATOM 2508 C CA . GLU A 1 325 ? -37.318 -15.760 18.597 1.00 60.45 ? 325 GLU A CA 1 ATOM 2509 C C . GLU A 1 325 ? -35.830 -15.383 18.487 1.00 60.94 ? 325 GLU A C 1 ATOM 2510 O O . GLU A 1 325 ? -35.220 -15.447 17.395 1.00 61.05 ? 325 GLU A O 1 ATOM 2511 C CB . GLU A 1 325 ? -38.174 -14.512 18.450 1.00 60.49 ? 325 GLU A CB 1 ATOM 2512 C CG . GLU A 1 325 ? -39.634 -14.819 18.399 1.00 61.10 ? 325 GLU A CG 1 ATOM 2513 C CD . GLU A 1 325 ? -40.049 -15.249 17.032 1.00 62.45 ? 325 GLU A CD 1 ATOM 2514 O OE1 . GLU A 1 325 ? -39.184 -15.236 16.129 1.00 62.88 ? 325 GLU A OE1 1 ATOM 2515 O OE2 . GLU A 1 325 ? -41.233 -15.595 16.851 1.00 64.06 ? 325 GLU A OE2 1 ATOM 2516 N N . GLY A 1 326 ? -35.250 -14.969 19.609 1.00 61.25 ? 326 GLY A N 1 ATOM 2517 C CA . GLY A 1 326 ? -33.902 -14.391 19.601 1.00 61.34 ? 326 GLY A CA 1 ATOM 2518 C C . GLY A 1 326 ? -32.726 -15.328 19.352 1.00 61.33 ? 326 GLY A C 1 ATOM 2519 O O . GLY A 1 326 ? -31.776 -14.963 18.668 1.00 61.64 ? 326 GLY A O 1 ATOM 2520 N N . THR A 1 327 ? -32.787 -16.540 19.883 1.00 61.16 ? 327 THR A N 1 ATOM 2521 C CA . THR A 1 327 ? -31.615 -17.387 19.944 1.00 61.26 ? 327 THR A CA 1 ATOM 2522 C C . THR A 1 327 ? -30.943 -17.577 18.599 1.00 61.77 ? 327 THR A C 1 ATOM 2523 O O . THR A 1 327 ? -29.724 -17.510 18.487 1.00 61.45 ? 327 THR A O 1 ATOM 2524 C CB . THR A 1 327 ? -31.959 -18.736 20.547 1.00 61.15 ? 327 THR A CB 1 ATOM 2525 O OG1 . THR A 1 327 ? -32.974 -19.358 19.766 1.00 60.39 ? 327 THR A OG1 1 ATOM 2526 C CG2 . THR A 1 327 ? -32.474 -18.551 21.956 1.00 60.83 ? 327 THR A CG2 1 ATOM 2527 N N . ALA A 1 328 ? -31.752 -17.797 17.573 1.00 62.61 ? 328 ALA A N 1 ATOM 2528 C CA . ALA A 1 328 ? -31.230 -18.118 16.245 1.00 63.18 ? 328 ALA A CA 1 ATOM 2529 C C . ALA A 1 328 ? -30.110 -17.190 15.798 1.00 63.41 ? 328 ALA A C 1 ATOM 2530 O O . ALA A 1 328 ? -29.261 -17.575 14.987 1.00 63.47 ? 328 ALA A O 1 ATOM 2531 C CB . ALA A 1 328 ? -32.354 -18.136 15.205 1.00 63.19 ? 328 ALA A CB 1 ATOM 2532 N N . PHE A 1 329 ? -30.112 -15.971 16.320 1.00 63.48 ? 329 PHE A N 1 ATOM 2533 C CA . PHE A 1 329 ? -29.228 -14.958 15.795 1.00 63.83 ? 329 PHE A CA 1 ATOM 2534 C C . PHE A 1 329 ? -27.961 -14.877 16.620 1.00 64.29 ? 329 PHE A C 1 ATOM 2535 O O . PHE A 1 329 ? -26.920 -14.407 16.171 1.00 64.14 ? 329 PHE A O 1 ATOM 2536 C CB . PHE A 1 329 ? -29.939 -13.601 15.761 1.00 63.46 ? 329 PHE A CB 1 ATOM 2537 C CG . PHE A 1 329 ? -31.179 -13.586 14.915 1.00 63.01 ? 329 PHE A CG 1 ATOM 2538 C CD1 . PHE A 1 329 ? -32.393 -13.983 15.448 1.00 63.23 ? 329 PHE A CD1 1 ATOM 2539 C CD2 . PHE A 1 329 ? -31.139 -13.178 13.582 1.00 61.69 ? 329 PHE A CD2 1 ATOM 2540 C CE1 . PHE A 1 329 ? -33.545 -13.965 14.673 1.00 61.95 ? 329 PHE A CE1 1 ATOM 2541 C CE2 . PHE A 1 329 ? -32.286 -13.165 12.801 1.00 60.19 ? 329 PHE A CE2 1 ATOM 2542 C CZ . PHE A 1 329 ? -33.482 -13.559 13.337 1.00 60.56 ? 329 PHE A CZ 1 ATOM 2543 N N . LEU A 1 330 ? -28.049 -15.324 17.852 1.00 64.96 ? 330 LEU A N 1 ATOM 2544 C CA . LEU A 1 330 ? -26.894 -15.205 18.716 1.00 65.86 ? 330 LEU A CA 1 ATOM 2545 C C . LEU A 1 330 ? -25.654 -15.785 18.028 1.00 66.81 ? 330 LEU A C 1 ATOM 2546 O O . LEU A 1 330 ? -24.547 -15.255 18.174 1.00 67.07 ? 330 LEU A O 1 ATOM 2547 C CB . LEU A 1 330 ? -27.157 -15.877 20.065 1.00 65.45 ? 330 LEU A CB 1 ATOM 2548 C CG . LEU A 1 330 ? -28.378 -15.182 20.684 1.00 64.89 ? 330 LEU A CG 1 ATOM 2549 C CD1 . LEU A 1 330 ? -28.830 -15.730 22.048 1.00 63.36 ? 330 LEU A CD1 1 ATOM 2550 C CD2 . LEU A 1 330 ? -28.117 -13.672 20.733 1.00 63.21 ? 330 LEU A CD2 1 ATOM 2551 N N . VAL A 1 331 ? -25.837 -16.855 17.256 1.00 67.41 ? 331 VAL A N 1 ATOM 2552 C CA . VAL A 1 331 ? -24.694 -17.614 16.754 1.00 67.83 ? 331 VAL A CA 1 ATOM 2553 C C . VAL A 1 331 ? -24.020 -16.986 15.522 1.00 68.45 ? 331 VAL A C 1 ATOM 2554 O O . VAL A 1 331 ? -23.111 -17.562 14.950 1.00 69.10 ? 331 VAL A O 1 ATOM 2555 C CB . VAL A 1 331 ? -25.064 -19.085 16.490 1.00 67.54 ? 331 VAL A CB 1 ATOM 2556 C CG1 . VAL A 1 331 ? -25.314 -19.809 17.786 1.00 67.62 ? 331 VAL A CG1 1 ATOM 2557 C CG2 . VAL A 1 331 ? -26.276 -19.175 15.617 1.00 67.86 ? 331 VAL A CG2 1 ATOM 2558 N N . TYR A 1 332 ? -24.455 -15.807 15.113 1.00 68.71 ? 332 TYR A N 1 ATOM 2559 C CA . TYR A 1 332 ? -23.862 -15.158 13.972 1.00 68.95 ? 332 TYR A CA 1 ATOM 2560 C C . TYR A 1 332 ? -23.092 -13.925 14.407 1.00 69.68 ? 332 TYR A C 1 ATOM 2561 O O . TYR A 1 332 ? -23.060 -12.918 13.700 1.00 69.57 ? 332 TYR A O 1 ATOM 2562 C CB . TYR A 1 332 ? -24.951 -14.752 12.986 1.00 68.81 ? 332 TYR A CB 1 ATOM 2563 C CG . TYR A 1 332 ? -25.546 -15.905 12.247 1.00 68.48 ? 332 TYR A CG 1 ATOM 2564 C CD1 . TYR A 1 332 ? -26.264 -16.869 12.910 1.00 68.82 ? 332 TYR A CD1 1 ATOM 2565 C CD2 . TYR A 1 332 ? -25.383 -16.033 10.884 1.00 68.47 ? 332 TYR A CD2 1 ATOM 2566 C CE1 . TYR A 1 332 ? -26.809 -17.929 12.237 1.00 69.03 ? 332 TYR A CE1 1 ATOM 2567 C CE2 . TYR A 1 332 ? -25.918 -17.084 10.208 1.00 68.45 ? 332 TYR A CE2 1 ATOM 2568 C CZ . TYR A 1 332 ? -26.636 -18.027 10.883 1.00 68.98 ? 332 TYR A CZ 1 ATOM 2569 O OH . TYR A 1 332 ? -27.167 -19.094 10.208 1.00 69.93 ? 332 TYR A OH 1 ATOM 2570 N N . GLY A 1 333 ? -22.488 -13.982 15.583 1.00 70.57 ? 333 GLY A N 1 ATOM 2571 C CA . GLY A 1 333 ? -21.705 -12.846 16.042 1.00 71.46 ? 333 GLY A CA 1 ATOM 2572 C C . GLY A 1 333 ? -21.627 -12.568 17.528 1.00 71.97 ? 333 GLY A C 1 ATOM 2573 O O . GLY A 1 333 ? -20.769 -11.817 17.958 1.00 72.03 ? 333 GLY A O 1 ATOM 2574 N N . ALA A 1 334 ? -22.514 -13.139 18.331 1.00 72.95 ? 334 ALA A N 1 ATOM 2575 C CA . ALA A 1 334 ? -22.452 -12.868 19.781 1.00 73.73 ? 334 ALA A CA 1 ATOM 2576 C C . ALA A 1 334 ? -21.368 -13.715 20.403 1.00 74.16 ? 334 ALA A C 1 ATOM 2577 O O . ALA A 1 334 ? -21.417 -14.946 20.328 1.00 74.30 ? 334 ALA A O 1 ATOM 2578 C CB . ALA A 1 334 ? -23.782 -13.104 20.477 1.00 73.57 ? 334 ALA A CB 1 ATOM 2579 N N . PRO A 1 335 ? -20.370 -13.045 20.989 1.00 74.42 ? 335 PRO A N 1 ATOM 2580 C CA . PRO A 1 335 ? -19.172 -13.613 21.549 1.00 74.70 ? 335 PRO A CA 1 ATOM 2581 C C . PRO A 1 335 ? -19.551 -14.602 22.625 1.00 75.15 ? 335 PRO A C 1 ATOM 2582 O O . PRO A 1 335 ? -20.226 -14.240 23.580 1.00 75.53 ? 335 PRO A O 1 ATOM 2583 C CB . PRO A 1 335 ? -18.493 -12.395 22.156 1.00 74.85 ? 335 PRO A CB 1 ATOM 2584 C CG . PRO A 1 335 ? -18.941 -11.272 21.299 1.00 74.45 ? 335 PRO A CG 1 ATOM 2585 C CD . PRO A 1 335 ? -20.375 -11.580 21.089 1.00 74.43 ? 335 PRO A CD 1 ATOM 2586 N N . GLY A 1 336 ? -19.156 -15.852 22.459 1.00 75.46 ? 336 GLY A N 1 ATOM 2587 C CA . GLY A 1 336 ? -19.451 -16.853 23.469 1.00 76.07 ? 336 GLY A CA 1 ATOM 2588 C C . GLY A 1 336 ? -20.415 -17.889 22.961 1.00 76.59 ? 336 GLY A C 1 ATOM 2589 O O . GLY A 1 336 ? -20.475 -18.998 23.478 1.00 76.50 ? 336 GLY A O 1 ATOM 2590 N N . PHE A 1 337 ? -21.158 -17.519 21.927 1.00 77.30 ? 337 PHE A N 1 ATOM 2591 C CA . PHE A 1 337 ? -22.198 -18.369 21.375 1.00 78.10 ? 337 PHE A CA 1 ATOM 2592 C C . PHE A 1 337 ? -21.707 -19.221 20.219 1.00 78.60 ? 337 PHE A C 1 ATOM 2593 O O . PHE A 1 337 ? -21.236 -18.711 19.195 1.00 78.41 ? 337 PHE A O 1 ATOM 2594 C CB . PHE A 1 337 ? -23.401 -17.531 20.922 1.00 78.32 ? 337 PHE A CB 1 ATOM 2595 C CG . PHE A 1 337 ? -24.146 -16.891 22.050 1.00 78.62 ? 337 PHE A CG 1 ATOM 2596 C CD1 . PHE A 1 337 ? -23.901 -15.574 22.407 1.00 79.17 ? 337 PHE A CD1 1 ATOM 2597 C CD2 . PHE A 1 337 ? -25.075 -17.619 22.777 1.00 79.15 ? 337 PHE A CD2 1 ATOM 2598 C CE1 . PHE A 1 337 ? -24.573 -14.989 23.462 1.00 79.32 ? 337 PHE A CE1 1 ATOM 2599 C CE2 . PHE A 1 337 ? -25.758 -17.049 23.836 1.00 78.74 ? 337 PHE A CE2 1 ATOM 2600 C CZ . PHE A 1 337 ? -25.509 -15.732 24.180 1.00 79.17 ? 337 PHE A CZ 1 ATOM 2601 N N . SER A 1 338 ? -21.822 -20.530 20.404 1.00 79.33 ? 338 SER A N 1 ATOM 2602 C CA . SER A 1 338 ? -21.622 -21.486 19.323 1.00 79.98 ? 338 SER A CA 1 ATOM 2603 C C . SER A 1 338 ? -22.842 -22.397 19.252 1.00 80.22 ? 338 SER A C 1 ATOM 2604 O O . SER A 1 338 ? -23.540 -22.588 20.247 1.00 80.24 ? 338 SER A O 1 ATOM 2605 C CB . SER A 1 338 ? -20.359 -22.314 19.555 1.00 79.98 ? 338 SER A CB 1 ATOM 2606 O OG . SER A 1 338 ? -20.326 -23.445 18.705 1.00 79.82 ? 338 SER A OG 1 ATOM 2607 N N . LYS A 1 339 ? -23.118 -22.947 18.077 1.00 80.50 ? 339 LYS A N 1 ATOM 2608 C CA . LYS A 1 339 ? -24.170 -23.928 17.999 1.00 80.77 ? 339 LYS A CA 1 ATOM 2609 C C . LYS A 1 339 ? -23.684 -25.223 18.613 1.00 81.22 ? 339 LYS A C 1 ATOM 2610 O O . LYS A 1 339 ? -24.475 -26.142 18.811 1.00 81.43 ? 339 LYS A O 1 ATOM 2611 C CB . LYS A 1 339 ? -24.651 -24.136 16.567 1.00 80.63 ? 339 LYS A CB 1 ATOM 2612 C CG . LYS A 1 339 ? -23.695 -24.836 15.639 1.00 80.59 ? 339 LYS A CG 1 ATOM 2613 C CD . LYS A 1 339 ? -24.452 -25.299 14.398 1.00 80.26 ? 339 LYS A CD 1 ATOM 2614 C CE . LYS A 1 339 ? -23.622 -26.222 13.571 1.00 79.70 ? 339 LYS A CE 1 ATOM 2615 N NZ . LYS A 1 339 ? -23.028 -27.237 14.472 1.00 79.38 ? 339 LYS A NZ 1 ATOM 2616 N N . ASP A 1 340 ? -22.394 -25.273 18.959 1.00 81.69 ? 340 ASP A N 1 ATOM 2617 C CA . ASP A 1 340 ? -21.764 -26.515 19.417 1.00 82.18 ? 340 ASP A CA 1 ATOM 2618 C C . ASP A 1 340 ? -21.555 -26.638 20.940 1.00 82.86 ? 340 ASP A C 1 ATOM 2619 O O . ASP A 1 340 ? -21.908 -27.663 21.514 1.00 83.17 ? 340 ASP A O 1 ATOM 2620 C CB . ASP A 1 340 ? -20.495 -26.808 18.604 1.00 81.84 ? 340 ASP A CB 1 ATOM 2621 C CG . ASP A 1 340 ? -20.786 -26.955 17.107 1.00 81.08 ? 340 ASP A CG 1 ATOM 2622 O OD1 . ASP A 1 340 ? -20.141 -26.293 16.277 1.00 80.33 ? 340 ASP A OD1 1 ATOM 2623 O OD2 . ASP A 1 340 ? -21.683 -27.724 16.745 1.00 80.22 ? 340 ASP A OD2 1 ATOM 2624 N N . ASN A 1 341 ? -21.004 -25.615 21.599 1.00 83.47 ? 341 ASN A N 1 ATOM 2625 C CA . ASN A 1 341 ? -21.030 -25.589 23.075 1.00 83.77 ? 341 ASN A CA 1 ATOM 2626 C C . ASN A 1 341 ? -22.319 -24.961 23.579 1.00 83.53 ? 341 ASN A C 1 ATOM 2627 O O . ASN A 1 341 ? -22.953 -24.189 22.869 1.00 83.51 ? 341 ASN A O 1 ATOM 2628 C CB . ASN A 1 341 ? -19.752 -24.996 23.744 1.00 84.04 ? 341 ASN A CB 1 ATOM 2629 C CG . ASN A 1 341 ? -19.397 -23.580 23.274 1.00 85.49 ? 341 ASN A CG 1 ATOM 2630 O OD1 . ASN A 1 341 ? -20.197 -22.903 22.627 1.00 86.37 ? 341 ASN A OD1 1 ATOM 2631 N ND2 . ASN A 1 341 ? -18.183 -23.135 23.617 1.00 87.27 ? 341 ASN A ND2 1 ATOM 2632 N N . ASN A 1 342 ? -22.731 -25.317 24.789 1.00 83.49 ? 342 ASN A N 1 ATOM 2633 C CA . ASN A 1 342 ? -24.002 -24.800 25.305 1.00 83.45 ? 342 ASN A CA 1 ATOM 2634 C C . ASN A 1 342 ? -23.912 -23.326 25.722 1.00 82.98 ? 342 ASN A C 1 ATOM 2635 O O . ASN A 1 342 ? -24.694 -22.822 26.536 1.00 82.75 ? 342 ASN A O 1 ATOM 2636 C CB . ASN A 1 342 ? -24.611 -25.707 26.389 1.00 83.61 ? 342 ASN A CB 1 ATOM 2637 C CG . ASN A 1 342 ? -23.963 -25.532 27.741 1.00 84.73 ? 342 ASN A CG 1 ATOM 2638 O OD1 . ASN A 1 342 ? -23.000 -24.778 27.912 1.00 85.99 ? 342 ASN A OD1 1 ATOM 2639 N ND2 . ASN A 1 342 ? -24.494 -26.238 28.723 1.00 86.36 ? 342 ASN A ND2 1 ATOM 2640 N N . SER A 1 343 ? -22.923 -22.653 25.147 1.00 82.46 ? 343 SER A N 1 ATOM 2641 C CA . SER A 1 343 ? -22.885 -21.202 25.101 1.00 82.12 ? 343 SER A CA 1 ATOM 2642 C C . SER A 1 343 ? -23.224 -20.424 26.390 1.00 81.99 ? 343 SER A C 1 ATOM 2643 O O . SER A 1 343 ? -23.913 -19.407 26.337 1.00 81.85 ? 343 SER A O 1 ATOM 2644 C CB . SER A 1 343 ? -23.760 -20.724 23.941 1.00 81.99 ? 343 SER A CB 1 ATOM 2645 O OG . SER A 1 343 ? -23.177 -21.072 22.700 1.00 81.51 ? 343 SER A OG 1 ATOM 2646 N N . ILE A 1 344 ? -22.730 -20.877 27.537 1.00 81.71 ? 344 ILE A N 1 ATOM 2647 C CA . ILE A 1 344 ? -22.794 -20.056 28.732 1.00 81.54 ? 344 ILE A CA 1 ATOM 2648 C C . ILE A 1 344 ? -21.856 -18.873 28.551 1.00 81.86 ? 344 ILE A C 1 ATOM 2649 O O . ILE A 1 344 ? -20.738 -19.043 28.102 1.00 82.02 ? 344 ILE A O 1 ATOM 2650 C CB . ILE A 1 344 ? -22.349 -20.833 29.947 1.00 81.37 ? 344 ILE A CB 1 ATOM 2651 C CG1 . ILE A 1 344 ? -23.195 -22.095 30.113 1.00 80.95 ? 344 ILE A CG1 1 ATOM 2652 C CG2 . ILE A 1 344 ? -22.444 -19.963 31.180 1.00 81.43 ? 344 ILE A CG2 1 ATOM 2653 C CD1 . ILE A 1 344 ? -24.579 -21.830 30.617 1.00 80.48 ? 344 ILE A CD1 1 ATOM 2654 N N . ILE A 1 345 ? -22.310 -17.669 28.869 1.00 82.29 ? 345 ILE A N 1 ATOM 2655 C CA . ILE A 1 345 ? -21.489 -16.475 28.660 1.00 82.64 ? 345 ILE A CA 1 ATOM 2656 C C . ILE A 1 345 ? -21.412 -15.623 29.927 1.00 83.10 ? 345 ILE A C 1 ATOM 2657 O O . ILE A 1 345 ? -22.212 -15.809 30.847 1.00 83.17 ? 345 ILE A O 1 ATOM 2658 C CB . ILE A 1 345 ? -22.017 -15.601 27.512 1.00 82.50 ? 345 ILE A CB 1 ATOM 2659 C CG1 . ILE A 1 345 ? -23.479 -15.227 27.765 1.00 82.76 ? 345 ILE A CG1 1 ATOM 2660 C CG2 . ILE A 1 345 ? -21.864 -16.311 26.195 1.00 82.03 ? 345 ILE A CG2 1 ATOM 2661 C CD1 . ILE A 1 345 ? -24.003 -14.146 26.862 1.00 82.95 ? 345 ILE A CD1 1 ATOM 2662 N N . THR A 1 346 ? -20.452 -14.692 29.965 1.00 83.46 ? 346 THR A N 1 ATOM 2663 C CA . THR A 1 346 ? -20.213 -13.845 31.137 1.00 83.53 ? 346 THR A CA 1 ATOM 2664 C C . THR A 1 346 ? -20.874 -12.488 31.013 1.00 83.95 ? 346 THR A C 1 ATOM 2665 O O . THR A 1 346 ? -21.143 -12.006 29.908 1.00 83.89 ? 346 THR A O 1 ATOM 2666 C CB . THR A 1 346 ? -18.704 -13.599 31.396 1.00 83.40 ? 346 THR A CB 1 ATOM 2667 O OG1 . THR A 1 346 ? -18.071 -13.115 30.208 1.00 82.46 ? 346 THR A OG1 1 ATOM 2668 C CG2 . THR A 1 346 ? -18.037 -14.860 31.828 1.00 83.38 ? 346 THR A CG2 1 ATOM 2669 N N . ARG A 1 347 ? -21.119 -11.871 32.161 1.00 84.42 ? 347 ARG A N 1 ATOM 2670 C CA . ARG A 1 347 ? -21.605 -10.512 32.192 1.00 85.12 ? 347 ARG A CA 1 ATOM 2671 C C . ARG A 1 347 ? -20.828 -9.646 31.199 1.00 85.33 ? 347 ARG A C 1 ATOM 2672 O O . ARG A 1 347 ? -21.405 -8.796 30.515 1.00 84.97 ? 347 ARG A O 1 ATOM 2673 C CB . ARG A 1 347 ? -21.471 -9.930 33.598 1.00 85.33 ? 347 ARG A CB 1 ATOM 2674 C CG . ARG A 1 347 ? -21.864 -8.462 33.658 1.00 86.20 ? 347 ARG A CG 1 ATOM 2675 C CD . ARG A 1 347 ? -21.716 -7.842 35.034 1.00 87.48 ? 347 ARG A CD 1 ATOM 2676 N NE . ARG A 1 347 ? -22.221 -6.469 35.034 1.00 88.20 ? 347 ARG A NE 1 ATOM 2677 C CZ . ARG A 1 347 ? -23.482 -6.138 35.306 1.00 88.27 ? 347 ARG A CZ 1 ATOM 2678 N NH1 . ARG A 1 347 ? -23.863 -4.865 35.271 1.00 87.96 ? 347 ARG A NH1 1 ATOM 2679 N NH2 . ARG A 1 347 ? -24.365 -7.080 35.612 1.00 87.83 ? 347 ARG A NH2 1 ATOM 2680 N N . LYS A 1 348 ? -19.517 -9.872 31.132 1.00 85.79 ? 348 LYS A N 1 ATOM 2681 C CA . LYS A 1 348 ? -18.647 -9.070 30.286 1.00 86.20 ? 348 LYS A CA 1 ATOM 2682 C C . LYS A 1 348 ? -19.029 -9.329 28.843 1.00 86.03 ? 348 LYS A C 1 ATOM 2683 O O . LYS A 1 348 ? -18.996 -8.427 28.008 1.00 86.05 ? 348 LYS A O 1 ATOM 2684 C CB . LYS A 1 348 ? -17.179 -9.435 30.515 1.00 86.54 ? 348 LYS A CB 1 ATOM 2685 C CG . LYS A 1 348 ? -16.170 -8.390 30.020 1.00 87.84 ? 348 LYS A CG 1 ATOM 2686 C CD . LYS A 1 348 ? -15.861 -7.411 31.138 1.00 90.60 ? 348 LYS A CD 1 ATOM 2687 C CE . LYS A 1 348 ? -14.414 -6.906 31.078 1.00 91.47 ? 348 LYS A CE 1 ATOM 2688 N NZ . LYS A 1 348 ? -14.223 -5.832 30.069 1.00 91.98 ? 348 LYS A NZ 1 ATOM 2689 N N . GLU A 1 349 ? -19.410 -10.572 28.563 1.00 85.84 ? 349 GLU A N 1 ATOM 2690 C CA . GLU A 1 349 ? -19.736 -10.989 27.204 1.00 85.69 ? 349 GLU A CA 1 ATOM 2691 C C . GLU A 1 349 ? -21.127 -10.528 26.817 1.00 85.31 ? 349 GLU A C 1 ATOM 2692 O O . GLU A 1 349 ? -21.386 -10.176 25.654 1.00 85.21 ? 349 GLU A O 1 ATOM 2693 C CB . GLU A 1 349 ? -19.624 -12.503 27.071 1.00 85.74 ? 349 GLU A CB 1 ATOM 2694 C CG . GLU A 1 349 ? -18.193 -12.977 27.014 1.00 86.14 ? 349 GLU A CG 1 ATOM 2695 C CD . GLU A 1 349 ? -18.067 -14.485 27.053 1.00 86.41 ? 349 GLU A CD 1 ATOM 2696 O OE1 . GLU A 1 349 ? -17.307 -15.028 26.230 1.00 86.61 ? 349 GLU A OE1 1 ATOM 2697 O OE2 . GLU A 1 349 ? -18.717 -15.129 27.901 1.00 86.05 ? 349 GLU A OE2 1 ATOM 2698 N N . PHE A 1 350 ? -22.013 -10.533 27.808 1.00 84.76 ? 350 PHE A N 1 ATOM 2699 C CA . PHE A 1 350 ? -23.345 -10.015 27.612 1.00 84.27 ? 350 PHE A CA 1 ATOM 2700 C C . PHE A 1 350 ? -23.248 -8.574 27.143 1.00 84.14 ? 350 PHE A C 1 ATOM 2701 O O . PHE A 1 350 ? -23.801 -8.210 26.108 1.00 84.02 ? 350 PHE A O 1 ATOM 2702 C CB . PHE A 1 350 ? -24.167 -10.114 28.890 1.00 84.07 ? 350 PHE A CB 1 ATOM 2703 C CG . PHE A 1 350 ? -25.527 -9.541 28.753 1.00 83.63 ? 350 PHE A CG 1 ATOM 2704 C CD1 . PHE A 1 350 ? -26.584 -10.326 28.369 1.00 84.07 ? 350 PHE A CD1 1 ATOM 2705 C CD2 . PHE A 1 350 ? -25.747 -8.204 28.966 1.00 84.08 ? 350 PHE A CD2 1 ATOM 2706 C CE1 . PHE A 1 350 ? -27.847 -9.785 28.224 1.00 84.53 ? 350 PHE A CE1 1 ATOM 2707 C CE2 . PHE A 1 350 ? -27.008 -7.655 28.827 1.00 84.35 ? 350 PHE A CE2 1 ATOM 2708 C CZ . PHE A 1 350 ? -28.059 -8.444 28.457 1.00 84.29 ? 350 PHE A CZ 1 ATOM 2709 N N . GLN A 1 351 ? -22.531 -7.754 27.900 1.00 84.11 ? 351 GLN A N 1 ATOM 2710 C CA . GLN A 1 351 ? -22.296 -6.392 27.476 1.00 84.18 ? 351 GLN A CA 1 ATOM 2711 C C . GLN A 1 351 ? -21.782 -6.426 26.047 1.00 84.19 ? 351 GLN A C 1 ATOM 2712 O O . GLN A 1 351 ? -22.200 -5.635 25.208 1.00 84.03 ? 351 GLN A O 1 ATOM 2713 C CB . GLN A 1 351 ? -21.293 -5.705 28.389 1.00 84.23 ? 351 GLN A CB 1 ATOM 2714 C CG . GLN A 1 351 ? -21.884 -5.153 29.663 1.00 85.05 ? 351 GLN A CG 1 ATOM 2715 C CD . GLN A 1 351 ? -20.953 -5.338 30.840 1.00 86.74 ? 351 GLN A CD 1 ATOM 2716 O OE1 . GLN A 1 351 ? -19.766 -5.631 30.667 1.00 88.21 ? 351 GLN A OE1 1 ATOM 2717 N NE2 . GLN A 1 351 ? -21.484 -5.182 32.050 1.00 86.95 ? 351 GLN A NE2 1 ATOM 2718 N N . GLU A 1 352 ? -20.888 -7.368 25.765 1.00 84.25 ? 352 GLU A N 1 ATOM 2719 C CA . GLU A 1 352 ? -20.285 -7.457 24.441 1.00 84.41 ? 352 GLU A CA 1 ATOM 2720 C C . GLU A 1 352 ? -21.336 -7.758 23.365 1.00 83.99 ? 352 GLU A C 1 ATOM 2721 O O . GLU A 1 352 ? -21.367 -7.117 22.297 1.00 83.93 ? 352 GLU A O 1 ATOM 2722 C CB . GLU A 1 352 ? -19.163 -8.499 24.426 1.00 84.80 ? 352 GLU A CB 1 ATOM 2723 C CG . GLU A 1 352 ? -17.829 -8.007 25.000 1.00 86.68 ? 352 GLU A CG 1 ATOM 2724 C CD . GLU A 1 352 ? -17.432 -6.617 24.486 1.00 89.18 ? 352 GLU A CD 1 ATOM 2725 O OE1 . GLU A 1 352 ? -17.727 -6.290 23.314 1.00 89.41 ? 352 GLU A OE1 1 ATOM 2726 O OE2 . GLU A 1 352 ? -16.826 -5.842 25.262 1.00 90.05 ? 352 GLU A OE2 1 ATOM 2727 N N . GLY A 1 353 ? -22.198 -8.732 23.658 1.00 83.24 ? 353 GLY A N 1 ATOM 2728 C CA . GLY A 1 353 ? -23.307 -9.068 22.776 1.00 82.08 ? 353 GLY A CA 1 ATOM 2729 C C . GLY A 1 353 ? -24.188 -7.875 22.467 1.00 81.41 ? 353 GLY A C 1 ATOM 2730 O O . GLY A 1 353 ? -24.628 -7.693 21.329 1.00 81.52 ? 353 GLY A O 1 ATOM 2731 N N . LEU A 1 354 ? -24.442 -7.047 23.472 1.00 80.53 ? 354 LEU A N 1 ATOM 2732 C CA . LEU A 1 354 ? -25.291 -5.891 23.271 1.00 79.72 ? 354 LEU A CA 1 ATOM 2733 C C . LEU A 1 354 ? -24.732 -4.953 22.236 1.00 79.40 ? 354 LEU A C 1 ATOM 2734 O O . LEU A 1 354 ? -25.492 -4.344 21.492 1.00 79.00 ? 354 LEU A O 1 ATOM 2735 C CB . LEU A 1 354 ? -25.509 -5.147 24.572 1.00 79.70 ? 354 LEU A CB 1 ATOM 2736 C CG . LEU A 1 354 ? -26.565 -5.794 25.460 1.00 79.51 ? 354 LEU A CG 1 ATOM 2737 C CD1 . LEU A 1 354 ? -26.755 -5.006 26.742 1.00 78.98 ? 354 LEU A CD1 1 ATOM 2738 C CD2 . LEU A 1 354 ? -27.862 -5.882 24.688 1.00 79.79 ? 354 LEU A CD2 1 ATOM 2739 N N . LYS A 1 355 ? -23.403 -4.854 22.181 1.00 79.38 ? 355 LYS A N 1 ATOM 2740 C CA . LYS A 1 355 ? -22.741 -3.913 21.281 1.00 79.38 ? 355 LYS A CA 1 ATOM 2741 C C . LYS A 1 355 ? -22.976 -4.355 19.874 1.00 79.03 ? 355 LYS A C 1 ATOM 2742 O O . LYS A 1 355 ? -23.069 -3.523 18.967 1.00 78.98 ? 355 LYS A O 1 ATOM 2743 C CB . LYS A 1 355 ? -21.236 -3.863 21.505 1.00 79.52 ? 355 LYS A CB 1 ATOM 2744 C CG . LYS A 1 355 ? -20.806 -3.882 22.933 1.00 81.03 ? 355 LYS A CG 1 ATOM 2745 C CD . LYS A 1 355 ? -19.407 -3.291 23.096 1.00 84.32 ? 355 LYS A CD 1 ATOM 2746 C CE . LYS A 1 355 ? -18.954 -3.285 24.576 1.00 85.98 ? 355 LYS A CE 1 ATOM 2747 N NZ . LYS A 1 355 ? -17.632 -2.628 24.827 1.00 86.60 ? 355 LYS A NZ 1 ATOM 2748 N N . ILE A 1 356 ? -23.064 -5.675 19.713 1.00 78.64 ? 356 ILE A N 1 ATOM 2749 C CA . ILE A 1 356 ? -23.221 -6.294 18.410 1.00 78.31 ? 356 ILE A CA 1 ATOM 2750 C C . ILE A 1 356 ? -24.600 -6.022 17.833 1.00 78.04 ? 356 ILE A C 1 ATOM 2751 O O . ILE A 1 356 ? -24.733 -5.695 16.642 1.00 78.12 ? 356 ILE A O 1 ATOM 2752 C CB . ILE A 1 356 ? -23.018 -7.804 18.474 1.00 78.29 ? 356 ILE A CB 1 ATOM 2753 C CG1 . ILE A 1 356 ? -21.540 -8.146 18.684 1.00 78.13 ? 356 ILE A CG1 1 ATOM 2754 C CG2 . ILE A 1 356 ? -23.490 -8.419 17.203 1.00 78.79 ? 356 ILE A CG2 1 ATOM 2755 C CD1 . ILE A 1 356 ? -20.633 -7.594 17.625 1.00 77.19 ? 356 ILE A CD1 1 ATOM 2756 N N . PHE A 1 357 ? -25.621 -6.149 18.677 1.00 77.42 ? 357 PHE A N 1 ATOM 2757 C CA . PHE A 1 357 ? -27.006 -6.022 18.220 1.00 76.91 ? 357 PHE A CA 1 ATOM 2758 C C . PHE A 1 357 ? -27.546 -4.607 18.234 1.00 76.94 ? 357 PHE A C 1 ATOM 2759 O O . PHE A 1 357 ? -28.511 -4.298 17.547 1.00 76.64 ? 357 PHE A O 1 ATOM 2760 C CB . PHE A 1 357 ? -27.919 -6.934 19.027 1.00 76.67 ? 357 PHE A CB 1 ATOM 2761 C CG . PHE A 1 357 ? -27.796 -8.363 18.656 1.00 75.27 ? 357 PHE A CG 1 ATOM 2762 C CD1 . PHE A 1 357 ? -28.476 -8.861 17.572 1.00 74.15 ? 357 PHE A CD1 1 ATOM 2763 C CD2 . PHE A 1 357 ? -26.973 -9.201 19.366 1.00 74.27 ? 357 PHE A CD2 1 ATOM 2764 C CE1 . PHE A 1 357 ? -28.353 -10.175 17.220 1.00 73.57 ? 357 PHE A CE1 1 ATOM 2765 C CE2 . PHE A 1 357 ? -26.849 -10.515 19.017 1.00 73.47 ? 357 PHE A CE2 1 ATOM 2766 C CZ . PHE A 1 357 ? -27.538 -11.005 17.950 1.00 73.52 ? 357 PHE A CZ 1 ATOM 2767 N N . PHE A 1 358 ? -26.930 -3.751 19.029 1.00 77.21 ? 358 PHE A N 1 ATOM 2768 C CA . PHE A 1 358 ? -27.310 -2.357 19.041 1.00 77.67 ? 358 PHE A CA 1 ATOM 2769 C C . PHE A 1 358 ? -26.069 -1.512 18.830 1.00 78.47 ? 358 PHE A C 1 ATOM 2770 O O . PHE A 1 358 ? -25.546 -0.936 19.771 1.00 78.91 ? 358 PHE A O 1 ATOM 2771 C CB . PHE A 1 358 ? -27.976 -2.019 20.363 1.00 77.14 ? 358 PHE A CB 1 ATOM 2772 C CG . PHE A 1 358 ? -29.045 -2.984 20.751 1.00 76.00 ? 358 PHE A CG 1 ATOM 2773 C CD1 . PHE A 1 358 ? -28.731 -4.161 21.393 1.00 74.81 ? 358 PHE A CD1 1 ATOM 2774 C CD2 . PHE A 1 358 ? -30.372 -2.722 20.460 1.00 75.51 ? 358 PHE A CD2 1 ATOM 2775 C CE1 . PHE A 1 358 ? -29.723 -5.049 21.752 1.00 74.30 ? 358 PHE A CE1 1 ATOM 2776 C CE2 . PHE A 1 358 ? -31.365 -3.610 20.819 1.00 74.00 ? 358 PHE A CE2 1 ATOM 2777 C CZ . PHE A 1 358 ? -31.037 -4.770 21.464 1.00 73.83 ? 358 PHE A CZ 1 ATOM 2778 N N . PRO A 1 359 ? -25.586 -1.438 17.586 1.00 79.15 ? 359 PRO A N 1 ATOM 2779 C CA . PRO A 1 359 ? -24.323 -0.759 17.362 1.00 79.43 ? 359 PRO A CA 1 ATOM 2780 C C . PRO A 1 359 ? -24.443 0.745 17.610 1.00 79.57 ? 359 PRO A C 1 ATOM 2781 O O . PRO A 1 359 ? -23.728 1.283 18.466 1.00 80.04 ? 359 PRO A O 1 ATOM 2782 C CB . PRO A 1 359 ? -24.017 -1.053 15.894 1.00 79.54 ? 359 PRO A CB 1 ATOM 2783 C CG . PRO A 1 359 ? -25.339 -1.303 15.263 1.00 79.82 ? 359 PRO A CG 1 ATOM 2784 C CD . PRO A 1 359 ? -26.265 -1.805 16.334 1.00 79.43 ? 359 PRO A CD 1 ATOM 2785 N N . GLY A 1 360 ? -25.351 1.411 16.901 1.00 79.19 ? 360 GLY A N 1 ATOM 2786 C CA . GLY A 1 360 ? -25.504 2.861 17.041 1.00 78.72 ? 360 GLY A CA 1 ATOM 2787 C C . GLY A 1 360 ? -26.074 3.392 18.357 1.00 78.16 ? 360 GLY A C 1 ATOM 2788 O O . GLY A 1 360 ? -26.105 4.596 18.579 1.00 78.32 ? 360 GLY A O 1 ATOM 2789 N N . VAL A 1 361 ? -26.525 2.510 19.236 1.00 77.49 ? 361 VAL A N 1 ATOM 2790 C CA . VAL A 1 361 ? -27.236 2.949 20.438 1.00 76.74 ? 361 VAL A CA 1 ATOM 2791 C C . VAL A 1 361 ? -26.339 3.553 21.552 1.00 76.23 ? 361 VAL A C 1 ATOM 2792 O O . VAL A 1 361 ? -25.370 2.931 21.993 1.00 75.90 ? 361 VAL A O 1 ATOM 2793 C CB . VAL A 1 361 ? -28.134 1.808 20.988 1.00 76.72 ? 361 VAL A CB 1 ATOM 2794 C CG1 . VAL A 1 361 ? -28.542 2.076 22.435 1.00 76.21 ? 361 VAL A CG1 1 ATOM 2795 C CG2 . VAL A 1 361 ? -29.344 1.623 20.089 1.00 76.12 ? 361 VAL A CG2 1 ATOM 2796 N N . SER A 1 362 ? -26.692 4.770 21.980 1.00 75.48 ? 362 SER A N 1 ATOM 2797 C CA . SER A 1 362 ? -26.045 5.473 23.087 1.00 74.78 ? 362 SER A CA 1 ATOM 2798 C C . SER A 1 362 ? -25.580 4.532 24.189 1.00 74.63 ? 362 SER A C 1 ATOM 2799 O O . SER A 1 362 ? -26.167 3.469 24.405 1.00 74.62 ? 362 SER A O 1 ATOM 2800 C CB . SER A 1 362 ? -27.019 6.485 23.695 1.00 74.96 ? 362 SER A CB 1 ATOM 2801 O OG . SER A 1 362 ? -27.703 5.965 24.833 1.00 74.05 ? 362 SER A OG 1 ATOM 2802 N N . GLU A 1 363 ? -24.549 4.945 24.920 1.00 74.23 ? 363 GLU A N 1 ATOM 2803 C CA . GLU A 1 363 ? -24.000 4.106 25.973 1.00 73.65 ? 363 GLU A CA 1 ATOM 2804 C C . GLU A 1 363 ? -25.041 3.913 27.056 1.00 73.34 ? 363 GLU A C 1 ATOM 2805 O O . GLU A 1 363 ? -25.150 2.849 27.655 1.00 73.40 ? 363 GLU A O 1 ATOM 2806 C CB . GLU A 1 363 ? -22.737 4.735 26.544 1.00 73.68 ? 363 GLU A CB 1 ATOM 2807 C CG . GLU A 1 363 ? -21.826 3.724 27.207 1.00 73.93 ? 363 GLU A CG 1 ATOM 2808 C CD . GLU A 1 363 ? -21.286 2.702 26.221 0.50 74.07 ? 363 GLU A CD 1 ATOM 2809 O OE1 . GLU A 1 363 ? -21.477 1.491 26.454 0.50 73.85 ? 363 GLU A OE1 1 ATOM 2810 O OE2 . GLU A 1 363 ? -20.680 3.107 25.204 0.50 73.97 ? 363 GLU A OE2 1 ATOM 2811 N N . PHE A 1 364 ? -25.822 4.964 27.285 1.00 73.10 ? 364 PHE A N 1 ATOM 2812 C CA . PHE A 1 364 ? -26.939 4.931 28.220 1.00 72.47 ? 364 PHE A CA 1 ATOM 2813 C C . PHE A 1 364 ? -27.955 3.887 27.780 1.00 71.99 ? 364 PHE A C 1 ATOM 2814 O O . PHE A 1 364 ? -28.417 3.079 28.567 1.00 71.04 ? 364 PHE A O 1 ATOM 2815 C CB . PHE A 1 364 ? -27.604 6.305 28.256 1.00 72.43 ? 364 PHE A CB 1 ATOM 2816 C CG . PHE A 1 364 ? -28.872 6.345 29.055 1.00 72.01 ? 364 PHE A CG 1 ATOM 2817 C CD1 . PHE A 1 364 ? -30.050 6.792 28.483 1.00 71.05 ? 364 PHE A CD1 1 ATOM 2818 C CD2 . PHE A 1 364 ? -28.889 5.944 30.386 1.00 71.18 ? 364 PHE A CD2 1 ATOM 2819 C CE1 . PHE A 1 364 ? -31.232 6.831 29.227 1.00 70.06 ? 364 PHE A CE1 1 ATOM 2820 C CE2 . PHE A 1 364 ? -30.073 5.984 31.135 1.00 69.93 ? 364 PHE A CE2 1 ATOM 2821 C CZ . PHE A 1 364 ? -31.239 6.418 30.551 1.00 69.46 ? 364 PHE A CZ 1 ATOM 2822 N N . GLY A 1 365 ? -28.291 3.924 26.497 1.00 71.89 ? 365 GLY A N 1 ATOM 2823 C CA . GLY A 1 365 ? -29.272 3.017 25.933 1.00 71.70 ? 365 GLY A CA 1 ATOM 2824 C C . GLY A 1 365 ? -28.921 1.584 26.227 1.00 71.55 ? 365 GLY A C 1 ATOM 2825 O O . GLY A 1 365 ? -29.777 0.796 26.597 1.00 71.70 ? 365 GLY A O 1 ATOM 2826 N N . LYS A 1 366 ? -27.656 1.235 26.066 1.00 71.43 ? 366 LYS A N 1 ATOM 2827 C CA . LYS A 1 366 ? -27.256 -0.147 26.261 1.00 71.29 ? 366 LYS A CA 1 ATOM 2828 C C . LYS A 1 366 ? -27.258 -0.470 27.740 1.00 71.31 ? 366 LYS A C 1 ATOM 2829 O O . LYS A 1 366 ? -27.510 -1.590 28.158 1.00 70.87 ? 366 LYS A O 1 ATOM 2830 C CB . LYS A 1 366 ? -25.901 -0.406 25.615 1.00 71.25 ? 366 LYS A CB 1 ATOM 2831 C CG . LYS A 1 366 ? -25.874 -0.017 24.128 1.00 71.57 ? 366 LYS A CG 1 ATOM 2832 C CD . LYS A 1 366 ? -24.746 -0.693 23.356 1.00 71.89 ? 366 LYS A CD 1 ATOM 2833 C CE . LYS A 1 366 ? -23.416 0.015 23.541 1.00 72.42 ? 366 LYS A CE 1 ATOM 2834 N NZ . LYS A 1 366 ? -23.433 1.329 22.852 1.00 72.79 ? 366 LYS A NZ 1 ATOM 2835 N N . GLU A 1 367 ? -27.003 0.538 28.548 1.00 71.86 ? 367 GLU A N 1 ATOM 2836 C CA . GLU A 1 367 ? -27.088 0.363 29.980 1.00 72.48 ? 367 GLU A CA 1 ATOM 2837 C C . GLU A 1 367 ? -28.520 -0.014 30.439 1.00 72.24 ? 367 GLU A C 1 ATOM 2838 O O . GLU A 1 367 ? -28.701 -0.909 31.253 1.00 72.15 ? 367 GLU A O 1 ATOM 2839 C CB . GLU A 1 367 ? -26.602 1.642 30.659 1.00 72.79 ? 367 GLU A CB 1 ATOM 2840 C CG . GLU A 1 367 ? -25.114 1.756 30.855 0.50 74.18 ? 367 GLU A CG 1 ATOM 2841 C CD . GLU A 1 367 ? -24.729 1.529 32.313 0.50 76.67 ? 367 GLU A CD 1 ATOM 2842 O OE1 . GLU A 1 367 ? -24.069 2.423 32.917 1.00 77.97 ? 367 GLU A OE1 1 ATOM 2843 O OE2 . GLU A 1 367 ? -25.118 0.466 32.857 1.00 77.17 ? 367 GLU A OE2 1 ATOM 2844 N N . SER A 1 368 ? -29.526 0.672 29.908 1.00 72.02 ? 368 SER A N 1 ATOM 2845 C CA . SER A 1 368 ? -30.913 0.394 30.254 1.00 71.88 ? 368 SER A CA 1 ATOM 2846 C C . SER A 1 368 ? -31.270 -1.035 29.933 1.00 71.91 ? 368 SER A C 1 ATOM 2847 O O . SER A 1 368 ? -31.832 -1.760 30.760 1.00 71.89 ? 368 SER A O 1 ATOM 2848 C CB . SER A 1 368 ? -31.846 1.306 29.474 1.00 71.69 ? 368 SER A CB 1 ATOM 2849 O OG . SER A 1 368 ? -31.200 1.770 28.308 1.00 72.65 ? 368 SER A OG 1 ATOM 2850 N N . ILE A 1 369 ? -30.971 -1.443 28.710 1.00 71.90 ? 369 ILE A N 1 ATOM 2851 C CA . ILE A 1 369 ? -31.162 -2.832 28.366 1.00 71.92 ? 369 ILE A CA 1 ATOM 2852 C C . ILE A 1 369 ? -30.468 -3.727 29.386 1.00 72.51 ? 369 ILE A C 1 ATOM 2853 O O . ILE A 1 369 ? -31.100 -4.614 29.956 1.00 72.41 ? 369 ILE A O 1 ATOM 2854 C CB . ILE A 1 369 ? -30.659 -3.143 26.977 1.00 71.58 ? 369 ILE A CB 1 ATOM 2855 C CG1 . ILE A 1 369 ? -31.203 -2.119 25.991 1.00 70.79 ? 369 ILE A CG1 1 ATOM 2856 C CG2 . ILE A 1 369 ? -31.089 -4.529 26.577 1.00 71.46 ? 369 ILE A CG2 1 ATOM 2857 C CD1 . ILE A 1 369 ? -30.609 -2.257 24.622 1.00 69.36 ? 369 ILE A CD1 1 ATOM 2858 N N . LEU A 1 370 ? -29.185 -3.487 29.649 1.00 73.32 ? 370 LEU A N 1 ATOM 2859 C CA . LEU A 1 370 ? -28.494 -4.337 30.606 1.00 74.41 ? 370 LEU A CA 1 ATOM 2860 C C . LEU A 1 370 ? -29.308 -4.411 31.864 1.00 75.53 ? 370 LEU A C 1 ATOM 2861 O O . LEU A 1 370 ? -29.543 -5.490 32.404 1.00 75.51 ? 370 LEU A O 1 ATOM 2862 C CB . LEU A 1 370 ? -27.105 -3.814 30.954 1.00 74.16 ? 370 LEU A CB 1 ATOM 2863 C CG . LEU A 1 370 ? -26.282 -4.817 31.768 1.00 73.35 ? 370 LEU A CG 1 ATOM 2864 C CD1 . LEU A 1 370 ? -24.832 -4.669 31.425 1.00 73.70 ? 370 LEU A CD1 1 ATOM 2865 C CD2 . LEU A 1 370 ? -26.467 -4.613 33.244 1.00 74.34 ? 370 LEU A CD2 1 ATOM 2866 N N . PHE A 1 371 ? -29.744 -3.239 32.309 1.00 77.19 ? 371 PHE A N 1 ATOM 2867 C CA . PHE A 1 371 ? -30.365 -3.070 33.608 1.00 78.90 ? 371 PHE A CA 1 ATOM 2868 C C . PHE A 1 371 ? -31.722 -3.737 33.673 1.00 79.60 ? 371 PHE A C 1 ATOM 2869 O O . PHE A 1 371 ? -32.056 -4.383 34.666 1.00 79.74 ? 371 PHE A O 1 ATOM 2870 C CB . PHE A 1 371 ? -30.507 -1.580 33.918 1.00 79.40 ? 371 PHE A CB 1 ATOM 2871 C CG . PHE A 1 371 ? -31.279 -1.289 35.175 1.00 81.71 ? 371 PHE A CG 1 ATOM 2872 C CD1 . PHE A 1 371 ? -32.604 -0.875 35.112 1.00 83.30 ? 371 PHE A CD1 1 ATOM 2873 C CD2 . PHE A 1 371 ? -30.682 -1.425 36.422 1.00 83.82 ? 371 PHE A CD2 1 ATOM 2874 C CE1 . PHE A 1 371 ? -33.324 -0.605 36.269 1.00 84.34 ? 371 PHE A CE1 1 ATOM 2875 C CE2 . PHE A 1 371 ? -31.401 -1.157 37.586 1.00 84.86 ? 371 PHE A CE2 1 ATOM 2876 C CZ . PHE A 1 371 ? -32.725 -0.749 37.505 1.00 84.87 ? 371 PHE A CZ 1 ATOM 2877 N N . HIS A 1 372 ? -32.511 -3.590 32.618 1.00 80.45 ? 372 HIS A N 1 ATOM 2878 C CA . HIS A 1 372 ? -33.822 -4.160 32.661 1.00 81.37 ? 372 HIS A CA 1 ATOM 2879 C C . HIS A 1 372 ? -33.770 -5.666 32.604 1.00 81.71 ? 372 HIS A C 1 ATOM 2880 O O . HIS A 1 372 ? -34.500 -6.329 33.318 1.00 81.90 ? 372 HIS A O 1 ATOM 2881 C CB . HIS A 1 372 ? -34.692 -3.644 31.546 1.00 81.85 ? 372 HIS A CB 1 ATOM 2882 C CG . HIS A 1 372 ? -36.089 -4.177 31.605 1.00 84.52 ? 372 HIS A CG 1 ATOM 2883 N ND1 . HIS A 1 372 ? -37.170 -3.401 31.969 1.00 86.36 ? 372 HIS A ND1 1 ATOM 2884 C CD2 . HIS A 1 372 ? -36.577 -5.424 31.389 1.00 86.46 ? 372 HIS A CD2 1 ATOM 2885 C CE1 . HIS A 1 372 ? -38.268 -4.142 31.947 1.00 87.07 ? 372 HIS A CE1 1 ATOM 2886 N NE2 . HIS A 1 372 ? -37.936 -5.373 31.600 1.00 87.04 ? 372 HIS A NE2 1 ATOM 2887 N N . TYR A 1 373 ? -32.906 -6.225 31.770 1.00 82.46 ? 373 TYR A N 1 ATOM 2888 C CA . TYR A 1 373 ? -32.941 -7.671 31.579 1.00 83.24 ? 373 TYR A CA 1 ATOM 2889 C C . TYR A 1 373 ? -32.092 -8.479 32.547 1.00 84.68 ? 373 TYR A C 1 ATOM 2890 O O . TYR A 1 373 ? -32.321 -9.675 32.705 1.00 84.99 ? 373 TYR A O 1 ATOM 2891 C CB . TYR A 1 373 ? -32.597 -8.060 30.146 1.00 82.70 ? 373 TYR A CB 1 ATOM 2892 C CG . TYR A 1 373 ? -33.748 -7.963 29.174 1.00 81.26 ? 373 TYR A CG 1 ATOM 2893 C CD1 . TYR A 1 373 ? -34.633 -9.004 29.009 1.00 80.23 ? 373 TYR A CD1 1 ATOM 2894 C CD2 . TYR A 1 373 ? -33.929 -6.831 28.408 1.00 79.75 ? 373 TYR A CD2 1 ATOM 2895 C CE1 . TYR A 1 373 ? -35.673 -8.903 28.123 1.00 79.71 ? 373 TYR A CE1 1 ATOM 2896 C CE2 . TYR A 1 373 ? -34.952 -6.725 27.524 1.00 78.87 ? 373 TYR A CE2 1 ATOM 2897 C CZ . TYR A 1 373 ? -35.829 -7.751 27.379 1.00 79.12 ? 373 TYR A CZ 1 ATOM 2898 O OH . TYR A 1 373 ? -36.857 -7.603 26.461 1.00 78.44 ? 373 TYR A OH 1 ATOM 2899 N N . THR A 1 374 ? -31.110 -7.859 33.193 1.00 86.35 ? 374 THR A N 1 ATOM 2900 C CA . THR A 1 374 ? -30.220 -8.640 34.058 1.00 88.02 ? 374 THR A CA 1 ATOM 2901 C C . THR A 1 374 ? -30.496 -8.403 35.522 1.00 89.12 ? 374 THR A C 1 ATOM 2902 O O . THR A 1 374 ? -29.587 -8.241 36.325 1.00 89.11 ? 374 THR A O 1 ATOM 2903 C CB . THR A 1 374 ? -28.726 -8.387 33.779 1.00 88.07 ? 374 THR A CB 1 ATOM 2904 O OG1 . THR A 1 374 ? -28.379 -7.072 34.219 1.00 88.38 ? 374 THR A OG1 1 ATOM 2905 C CG2 . THR A 1 374 ? -28.416 -8.536 32.294 1.00 88.06 ? 374 THR A CG2 1 ATOM 2906 N N . ASP A 1 375 ? -31.769 -8.390 35.861 1.00 90.93 ? 375 ASP A N 1 ATOM 2907 C CA . ASP A 1 375 ? -32.177 -8.284 37.239 1.00 92.74 ? 375 ASP A CA 1 ATOM 2908 C C . ASP A 1 375 ? -32.569 -9.678 37.736 1.00 93.47 ? 375 ASP A C 1 ATOM 2909 O O . ASP A 1 375 ? -33.754 -10.006 37.808 1.00 93.60 ? 375 ASP A O 1 ATOM 2910 C CB . ASP A 1 375 ? -33.358 -7.334 37.307 1.00 93.23 ? 375 ASP A CB 1 ATOM 2911 C CG . ASP A 1 375 ? -33.744 -6.990 38.717 1.00 94.66 ? 375 ASP A CG 1 ATOM 2912 O OD1 . ASP A 1 375 ? -32.850 -6.907 39.593 1.00 95.63 ? 375 ASP A OD1 1 ATOM 2913 O OD2 . ASP A 1 375 ? -34.957 -6.797 38.938 1.00 96.46 ? 375 ASP A OD2 1 ATOM 2914 N N . TRP A 1 376 ? -31.567 -10.491 38.076 1.00 94.45 ? 376 TRP A N 1 ATOM 2915 C CA . TRP A 1 376 ? -31.751 -11.942 38.236 1.00 95.24 ? 376 TRP A CA 1 ATOM 2916 C C . TRP A 1 376 ? -32.716 -12.382 39.317 1.00 95.72 ? 376 TRP A C 1 ATOM 2917 O O . TRP A 1 376 ? -32.829 -11.753 40.378 1.00 95.80 ? 376 TRP A O 1 ATOM 2918 C CB . TRP A 1 376 ? -30.418 -12.647 38.480 1.00 95.32 ? 376 TRP A CB 1 ATOM 2919 C CG . TRP A 1 376 ? -29.462 -12.427 37.400 1.00 95.83 ? 376 TRP A CG 1 ATOM 2920 C CD1 . TRP A 1 376 ? -28.131 -12.200 37.523 1.00 96.69 ? 376 TRP A CD1 1 ATOM 2921 C CD2 . TRP A 1 376 ? -29.756 -12.383 36.007 1.00 96.05 ? 376 TRP A CD2 1 ATOM 2922 N NE1 . TRP A 1 376 ? -27.569 -12.023 36.282 1.00 96.97 ? 376 TRP A NE1 1 ATOM 2923 C CE2 . TRP A 1 376 ? -28.550 -12.129 35.335 1.00 96.12 ? 376 TRP A CE2 1 ATOM 2924 C CE3 . TRP A 1 376 ? -30.924 -12.531 35.263 1.00 96.13 ? 376 TRP A CE3 1 ATOM 2925 C CZ2 . TRP A 1 376 ? -28.476 -12.020 33.965 1.00 95.81 ? 376 TRP A CZ2 1 ATOM 2926 C CZ3 . TRP A 1 376 ? -30.850 -12.422 33.905 1.00 96.24 ? 376 TRP A CZ3 1 ATOM 2927 C CH2 . TRP A 1 376 ? -29.635 -12.171 33.266 1.00 96.12 ? 376 TRP A CH2 1 ATOM 2928 N N . VAL A 1 377 ? -33.375 -13.505 39.040 1.00 96.12 ? 377 VAL A N 1 ATOM 2929 C CA . VAL A 1 377 ? -34.306 -14.119 39.978 1.00 96.28 ? 377 VAL A CA 1 ATOM 2930 C C . VAL A 1 377 ? -33.563 -15.072 40.939 1.00 96.25 ? 377 VAL A C 1 ATOM 2931 O O . VAL A 1 377 ? -32.360 -14.924 41.204 1.00 95.78 ? 377 VAL A O 1 ATOM 2932 C CB . VAL A 1 377 ? -35.448 -14.876 39.232 1.00 96.26 ? 377 VAL A CB 1 ATOM 2933 C CG1 . VAL A 1 377 ? -36.800 -14.508 39.825 1.00 96.42 ? 377 VAL A CG1 1 ATOM 2934 C CG2 . VAL A 1 377 ? -35.438 -14.537 37.752 1.00 96.27 ? 377 VAL A CG2 1 ATOM 2935 N N . GLN A 1 380 ? -26.509 -16.363 40.512 1.00 103.37 ? 380 GLN A N 1 ATOM 2936 C CA . GLN A 1 380 ? -26.525 -17.749 40.981 1.00 103.71 ? 380 GLN A CA 1 ATOM 2937 C C . GLN A 1 380 ? -26.660 -18.818 39.865 1.00 103.56 ? 380 GLN A C 1 ATOM 2938 O O . GLN A 1 380 ? -25.968 -19.827 39.904 1.00 103.79 ? 380 GLN A O 1 ATOM 2939 C CB . GLN A 1 380 ? -27.580 -17.951 42.085 1.00 103.78 ? 380 GLN A CB 1 ATOM 2940 C CG . GLN A 1 380 ? -28.966 -18.383 41.604 1.00 104.51 ? 380 GLN A CG 1 ATOM 2941 C CD . GLN A 1 380 ? -29.875 -17.222 41.177 1.00 105.48 ? 380 GLN A CD 1 ATOM 2942 O OE1 . GLN A 1 380 ? -29.461 -16.300 40.465 1.00 104.65 ? 380 GLN A OE1 1 ATOM 2943 N NE2 . GLN A 1 380 ? -31.138 -17.293 41.591 1.00 105.37 ? 380 GLN A NE2 1 ATOM 2944 N N . ARG A 1 381 ? -27.547 -18.604 38.889 1.00 103.22 ? 381 ARG A N 1 ATOM 2945 C CA . ARG A 1 381 ? -27.710 -19.529 37.738 1.00 102.51 ? 381 ARG A CA 1 ATOM 2946 C C . ARG A 1 381 ? -26.821 -19.194 36.530 1.00 101.42 ? 381 ARG A C 1 ATOM 2947 O O . ARG A 1 381 ? -26.818 -18.063 36.035 1.00 101.31 ? 381 ARG A O 1 ATOM 2948 C CB . ARG A 1 381 ? -29.166 -19.587 37.282 1.00 102.82 ? 381 ARG A CB 1 ATOM 2949 C CG . ARG A 1 381 ? -30.173 -19.576 38.418 1.00 104.74 ? 381 ARG A CG 1 ATOM 2950 C CD . ARG A 1 381 ? -31.572 -19.950 37.946 1.00 108.01 ? 381 ARG A CD 1 ATOM 2951 N NE . ARG A 1 381 ? -31.838 -19.455 36.598 1.00 110.83 ? 381 ARG A NE 1 ATOM 2952 C CZ . ARG A 1 381 ? -31.833 -20.217 35.505 1.00 112.19 ? 381 ARG A CZ 1 ATOM 2953 N NH1 . ARG A 1 381 ? -32.080 -19.678 34.319 1.00 112.61 ? 381 ARG A NH1 1 ATOM 2954 N NH2 . ARG A 1 381 ? -31.571 -21.519 35.590 1.00 112.86 ? 381 ARG A NH2 1 ATOM 2955 N N . PRO A 1 382 ? -26.085 -20.198 36.036 1.00 100.36 ? 382 PRO A N 1 ATOM 2956 C CA . PRO A 1 382 ? -25.058 -20.052 35.003 1.00 99.50 ? 382 PRO A CA 1 ATOM 2957 C C . PRO A 1 382 ? -25.553 -19.471 33.672 1.00 98.60 ? 382 PRO A C 1 ATOM 2958 O O . PRO A 1 382 ? -24.891 -18.620 33.082 1.00 98.39 ? 382 PRO A O 1 ATOM 2959 C CB . PRO A 1 382 ? -24.564 -21.490 34.798 1.00 99.58 ? 382 PRO A CB 1 ATOM 2960 C CG . PRO A 1 382 ? -24.972 -22.226 36.020 1.00 99.79 ? 382 PRO A CG 1 ATOM 2961 C CD . PRO A 1 382 ? -26.236 -21.595 36.475 1.00 100.25 ? 382 PRO A CD 1 ATOM 2962 N N . GLU A 1 383 ? -26.708 -19.939 33.208 1.00 97.67 ? 383 GLU A N 1 ATOM 2963 C CA . GLU A 1 383 ? -27.249 -19.560 31.896 1.00 96.49 ? 383 GLU A CA 1 ATOM 2964 C C . GLU A 1 383 ? -27.860 -18.162 31.854 1.00 95.15 ? 383 GLU A C 1 ATOM 2965 O O . GLU A 1 383 ? -28.181 -17.661 30.780 1.00 95.14 ? 383 GLU A O 1 ATOM 2966 C CB . GLU A 1 383 ? -28.286 -20.591 31.414 1.00 96.87 ? 383 GLU A CB 1 ATOM 2967 C CG . GLU A 1 383 ? -29.353 -20.967 32.436 1.00 98.04 ? 383 GLU A CG 1 ATOM 2968 C CD . GLU A 1 383 ? -28.810 -21.885 33.520 1.00 100.59 ? 383 GLU A CD 1 ATOM 2969 O OE1 . GLU A 1 383 ? -29.123 -21.678 34.713 1.00 102.07 ? 383 GLU A OE1 1 ATOM 2970 O OE2 . GLU A 1 383 ? -28.044 -22.812 33.184 1.00 101.15 ? 383 GLU A OE2 1 ATOM 2971 N N . ASN A 1 384 ? -28.019 -17.540 33.017 1.00 93.36 ? 384 ASN A N 1 ATOM 2972 C CA . ASN A 1 384 ? -28.685 -16.252 33.111 1.00 91.39 ? 384 ASN A CA 1 ATOM 2973 C C . ASN A 1 384 ? -28.378 -15.355 31.939 1.00 90.01 ? 384 ASN A C 1 ATOM 2974 O O . ASN A 1 384 ? -29.260 -15.021 31.154 1.00 89.95 ? 384 ASN A O 1 ATOM 2975 C CB . ASN A 1 384 ? -28.311 -15.540 34.405 1.00 91.58 ? 384 ASN A CB 1 ATOM 2976 C CG . ASN A 1 384 ? -29.108 -16.032 35.588 1.00 91.69 ? 384 ASN A CG 1 ATOM 2977 O OD1 . ASN A 1 384 ? -30.031 -16.839 35.449 1.00 91.03 ? 384 ASN A OD1 1 ATOM 2978 N ND2 . ASN A 1 384 ? -28.760 -15.542 36.765 1.00 92.46 ? 384 ASN A ND2 1 ATOM 2979 N N . TYR A 1 385 ? -27.122 -14.956 31.816 1.00 88.33 ? 385 TYR A N 1 ATOM 2980 C CA . TYR A 1 385 ? -26.771 -14.007 30.783 1.00 86.71 ? 385 TYR A CA 1 ATOM 2981 C C . TYR A 1 385 ? -27.044 -14.571 29.405 1.00 85.47 ? 385 TYR A C 1 ATOM 2982 O O . TYR A 1 385 ? -27.446 -13.826 28.519 1.00 85.84 ? 385 TYR A O 1 ATOM 2983 C CB . TYR A 1 385 ? -25.322 -13.547 30.907 1.00 86.97 ? 385 TYR A CB 1 ATOM 2984 C CG . TYR A 1 385 ? -25.049 -12.633 32.088 1.00 87.58 ? 385 TYR A CG 1 ATOM 2985 C CD1 . TYR A 1 385 ? -25.372 -11.278 32.039 1.00 88.10 ? 385 TYR A CD1 1 ATOM 2986 C CD2 . TYR A 1 385 ? -24.450 -13.119 33.246 1.00 87.96 ? 385 TYR A CD2 1 ATOM 2987 C CE1 . TYR A 1 385 ? -25.113 -10.440 33.115 1.00 88.06 ? 385 TYR A CE1 1 ATOM 2988 C CE2 . TYR A 1 385 ? -24.185 -12.285 34.316 1.00 88.33 ? 385 TYR A CE2 1 ATOM 2989 C CZ . TYR A 1 385 ? -24.519 -10.949 34.244 1.00 88.44 ? 385 TYR A CZ 1 ATOM 2990 O OH . TYR A 1 385 ? -24.246 -10.117 35.304 1.00 89.12 ? 385 TYR A OH 1 ATOM 2991 N N . ARG A 1 386 ? -26.844 -15.874 29.212 1.00 83.54 ? 386 ARG A N 1 ATOM 2992 C CA . ARG A 1 386 ? -27.140 -16.480 27.914 1.00 81.65 ? 386 ARG A CA 1 ATOM 2993 C C . ARG A 1 386 ? -28.599 -16.254 27.502 1.00 80.63 ? 386 ARG A C 1 ATOM 2994 O O . ARG A 1 386 ? -28.897 -15.836 26.381 1.00 80.60 ? 386 ARG A O 1 ATOM 2995 C CB . ARG A 1 386 ? -26.858 -17.981 27.916 1.00 81.64 ? 386 ARG A CB 1 ATOM 2996 C CG . ARG A 1 386 ? -27.149 -18.633 26.579 1.00 80.50 ? 386 ARG A CG 1 ATOM 2997 C CD . ARG A 1 386 ? -27.003 -20.117 26.650 1.00 78.58 ? 386 ARG A CD 1 ATOM 2998 N NE . ARG A 1 386 ? -28.087 -20.711 27.403 1.00 77.95 ? 386 ARG A NE 1 ATOM 2999 C CZ . ARG A 1 386 ? -28.095 -21.979 27.797 1.00 77.65 ? 386 ARG A CZ 1 ATOM 3000 N NH1 . ARG A 1 386 ? -27.075 -22.768 27.504 1.00 77.38 ? 386 ARG A NH1 1 ATOM 3001 N NH2 . ARG A 1 386 ? -29.106 -22.460 28.499 1.00 77.05 ? 386 ARG A NH2 1 ATOM 3002 N N . GLU A 1 387 ? -29.518 -16.543 28.411 1.00 78.86 ? 387 GLU A N 1 ATOM 3003 C CA . GLU A 1 387 ? -30.917 -16.458 28.076 1.00 77.14 ? 387 GLU A CA 1 ATOM 3004 C C . GLU A 1 387 ? -31.335 -15.014 27.981 1.00 75.52 ? 387 GLU A C 1 ATOM 3005 O O . GLU A 1 387 ? -32.091 -14.622 27.103 1.00 75.71 ? 387 GLU A O 1 ATOM 3006 C CB . GLU A 1 387 ? -31.711 -17.183 29.124 1.00 77.25 ? 387 GLU A CB 1 ATOM 3007 C CG . GLU A 1 387 ? -31.290 -18.605 29.231 1.00 79.12 ? 387 GLU A CG 1 ATOM 3008 C CD . GLU A 1 387 ? -32.180 -19.405 30.155 1.00 82.32 ? 387 GLU A CD 1 ATOM 3009 O OE1 . GLU A 1 387 ? -32.365 -20.620 29.890 1.00 82.88 ? 387 GLU A OE1 1 ATOM 3010 O OE2 . GLU A 1 387 ? -32.694 -18.820 31.147 1.00 83.13 ? 387 GLU A OE2 1 ATOM 3011 N N . ALA A 1 388 ? -30.825 -14.212 28.887 1.00 73.28 ? 388 ALA A N 1 ATOM 3012 C CA . ALA A 1 388 ? -31.098 -12.812 28.837 1.00 71.30 ? 388 ALA A CA 1 ATOM 3013 C C . ALA A 1 388 ? -30.844 -12.232 27.459 1.00 69.97 ? 388 ALA A C 1 ATOM 3014 O O . ALA A 1 388 ? -31.685 -11.533 26.927 1.00 69.89 ? 388 ALA A O 1 ATOM 3015 C CB . ALA A 1 388 ? -30.258 -12.108 29.850 1.00 71.64 ? 388 ALA A CB 1 ATOM 3016 N N . LEU A 1 389 ? -29.682 -12.491 26.877 1.00 68.40 ? 389 LEU A N 1 ATOM 3017 C CA . LEU A 1 389 ? -29.370 -11.842 25.609 1.00 66.96 ? 389 LEU A CA 1 ATOM 3018 C C . LEU A 1 389 ? -30.290 -12.343 24.520 1.00 66.12 ? 389 LEU A C 1 ATOM 3019 O O . LEU A 1 389 ? -30.582 -11.627 23.567 1.00 66.13 ? 389 LEU A O 1 ATOM 3020 C CB . LEU A 1 389 ? -27.910 -12.032 25.199 1.00 66.90 ? 389 LEU A CB 1 ATOM 3021 C CG . LEU A 1 389 ? -27.562 -11.424 23.836 1.00 65.96 ? 389 LEU A CG 1 ATOM 3022 C CD1 . LEU A 1 389 ? -27.823 -9.952 23.849 1.00 64.75 ? 389 LEU A CD1 1 ATOM 3023 C CD2 . LEU A 1 389 ? -26.112 -11.676 23.495 1.00 65.86 ? 389 LEU A CD2 1 ATOM 3024 N N . GLY A 1 390 ? -30.746 -13.581 24.676 1.00 65.11 ? 390 GLY A N 1 ATOM 3025 C CA . GLY A 1 390 ? -31.687 -14.184 23.747 1.00 63.74 ? 390 GLY A CA 1 ATOM 3026 C C . GLY A 1 390 ? -32.955 -13.371 23.746 1.00 62.79 ? 390 GLY A C 1 ATOM 3027 O O . GLY A 1 390 ? -33.320 -12.787 22.735 1.00 62.82 ? 390 GLY A O 1 ATOM 3028 N N . ASP A 1 391 ? -33.609 -13.312 24.898 1.00 61.85 ? 391 ASP A N 1 ATOM 3029 C CA . ASP A 1 391 ? -34.829 -12.538 25.060 1.00 61.01 ? 391 ASP A CA 1 ATOM 3030 C C . ASP A 1 391 ? -34.693 -11.117 24.583 1.00 60.25 ? 391 ASP A C 1 ATOM 3031 O O . ASP A 1 391 ? -35.574 -10.594 23.933 1.00 60.24 ? 391 ASP A O 1 ATOM 3032 C CB . ASP A 1 391 ? -35.236 -12.508 26.514 1.00 61.38 ? 391 ASP A CB 1 ATOM 3033 C CG . ASP A 1 391 ? -35.867 -13.804 26.969 1.00 62.71 ? 391 ASP A CG 1 ATOM 3034 O OD1 . ASP A 1 391 ? -36.738 -14.322 26.227 1.00 63.81 ? 391 ASP A OD1 1 ATOM 3035 O OD2 . ASP A 1 391 ? -35.505 -14.292 28.072 1.00 63.60 ? 391 ASP A OD2 1 ATOM 3036 N N . VAL A 1 392 ? -33.594 -10.467 24.919 1.00 59.43 ? 392 VAL A N 1 ATOM 3037 C CA . VAL A 1 392 ? -33.382 -9.114 24.444 1.00 58.76 ? 392 VAL A CA 1 ATOM 3038 C C . VAL A 1 392 ? -33.643 -9.029 22.928 1.00 58.69 ? 392 VAL A C 1 ATOM 3039 O O . VAL A 1 392 ? -34.439 -8.207 22.447 1.00 58.24 ? 392 VAL A O 1 ATOM 3040 C CB . VAL A 1 392 ? -31.964 -8.643 24.763 1.00 58.59 ? 392 VAL A CB 1 ATOM 3041 C CG1 . VAL A 1 392 ? -31.686 -7.299 24.104 1.00 57.92 ? 392 VAL A CG1 1 ATOM 3042 C CG2 . VAL A 1 392 ? -31.775 -8.570 26.241 1.00 58.15 ? 392 VAL A CG2 1 ATOM 3043 N N . VAL A 1 393 ? -32.976 -9.896 22.178 1.00 58.36 ? 393 VAL A N 1 ATOM 3044 C CA . VAL A 1 393 ? -33.115 -9.873 20.744 1.00 58.13 ? 393 VAL A CA 1 ATOM 3045 C C . VAL A 1 393 ? -34.527 -10.313 20.354 1.00 58.35 ? 393 VAL A C 1 ATOM 3046 O O . VAL A 1 393 ? -35.156 -9.758 19.409 1.00 58.29 ? 393 VAL A O 1 ATOM 3047 C CB . VAL A 1 393 ? -32.070 -10.757 20.106 1.00 57.93 ? 393 VAL A CB 1 ATOM 3048 C CG1 . VAL A 1 393 ? -32.227 -10.747 18.595 1.00 57.32 ? 393 VAL A CG1 1 ATOM 3049 C CG2 . VAL A 1 393 ? -30.691 -10.286 20.546 1.00 57.15 ? 393 VAL A CG2 1 ATOM 3050 N N . GLY A 1 394 ? -35.021 -11.302 21.098 1.00 57.93 ? 394 GLY A N 1 ATOM 3051 C CA . GLY A 1 394 ? -36.328 -11.858 20.842 1.00 57.89 ? 394 GLY A CA 1 ATOM 3052 C C . GLY A 1 394 ? -37.337 -10.751 20.993 1.00 57.92 ? 394 GLY A C 1 ATOM 3053 O O . GLY A 1 394 ? -38.000 -10.357 20.021 1.00 58.31 ? 394 GLY A O 1 ATOM 3054 N N . ASP A 1 395 ? -37.407 -10.230 22.214 1.00 57.66 ? 395 ASP A N 1 ATOM 3055 C CA . ASP A 1 395 ? -38.399 -9.255 22.604 1.00 57.35 ? 395 ASP A CA 1 ATOM 3056 C C . ASP A 1 395 ? -38.330 -8.018 21.735 1.00 57.45 ? 395 ASP A C 1 ATOM 3057 O O . ASP A 1 395 ? -39.361 -7.526 21.286 1.00 57.98 ? 395 ASP A O 1 ATOM 3058 C CB . ASP A 1 395 ? -38.220 -8.879 24.071 1.00 57.25 ? 395 ASP A CB 1 ATOM 3059 C CG . ASP A 1 395 ? -38.492 -10.047 25.000 1.00 57.78 ? 395 ASP A CG 1 ATOM 3060 O OD1 . ASP A 1 395 ? -38.180 -9.970 26.212 1.00 58.31 ? 395 ASP A OD1 1 ATOM 3061 O OD2 . ASP A 1 395 ? -39.021 -11.064 24.510 1.00 58.45 ? 395 ASP A OD2 1 ATOM 3062 N N . TYR A 1 396 ? -37.126 -7.519 21.469 1.00 57.15 ? 396 TYR A N 1 ATOM 3063 C CA . TYR A 1 396 ? -36.989 -6.250 20.760 1.00 56.93 ? 396 TYR A CA 1 ATOM 3064 C C . TYR A 1 396 ? -37.308 -6.326 19.273 1.00 57.00 ? 396 TYR A C 1 ATOM 3065 O O . TYR A 1 396 ? -37.913 -5.422 18.722 1.00 56.94 ? 396 TYR A O 1 ATOM 3066 C CB . TYR A 1 396 ? -35.594 -5.700 20.964 1.00 56.82 ? 396 TYR A CB 1 ATOM 3067 C CG . TYR A 1 396 ? -35.191 -4.589 20.015 1.00 56.95 ? 396 TYR A CG 1 ATOM 3068 C CD1 . TYR A 1 396 ? -35.822 -3.362 20.038 1.00 57.11 ? 396 TYR A CD1 1 ATOM 3069 C CD2 . TYR A 1 396 ? -34.133 -4.755 19.144 1.00 56.35 ? 396 TYR A CD2 1 ATOM 3070 C CE1 . TYR A 1 396 ? -35.425 -2.347 19.200 1.00 56.20 ? 396 TYR A CE1 1 ATOM 3071 C CE2 . TYR A 1 396 ? -33.739 -3.759 18.316 1.00 56.33 ? 396 TYR A CE2 1 ATOM 3072 C CZ . TYR A 1 396 ? -34.381 -2.556 18.338 1.00 56.29 ? 396 TYR A CZ 1 ATOM 3073 O OH . TYR A 1 396 ? -33.965 -1.572 17.465 1.00 56.01 ? 396 TYR A OH 1 ATOM 3074 N N . ASN A 1 397 ? -36.911 -7.409 18.623 1.00 57.06 ? 397 ASN A N 1 ATOM 3075 C CA . ASN A 1 397 ? -37.073 -7.486 17.183 1.00 57.04 ? 397 ASN A CA 1 ATOM 3076 C C . ASN A 1 397 ? -38.367 -8.127 16.719 1.00 57.02 ? 397 ASN A C 1 ATOM 3077 O O . ASN A 1 397 ? -38.762 -7.973 15.554 1.00 56.34 ? 397 ASN A O 1 ATOM 3078 C CB . ASN A 1 397 ? -35.930 -8.271 16.579 1.00 56.92 ? 397 ASN A CB 1 ATOM 3079 C CG . ASN A 1 397 ? -34.635 -7.602 16.770 1.00 56.71 ? 397 ASN A CG 1 ATOM 3080 O OD1 . ASN A 1 397 ? -34.257 -6.698 16.003 1.00 55.24 ? 397 ASN A OD1 1 ATOM 3081 N ND2 . ASN A 1 397 ? -33.919 -8.032 17.803 1.00 56.12 ? 397 ASN A ND2 1 ATOM 3082 N N . PHE A 1 398 ? -39.002 -8.884 17.610 1.00 56.79 ? 398 PHE A N 1 ATOM 3083 C CA . PHE A 1 398 ? -40.082 -9.722 17.166 1.00 56.64 ? 398 PHE A CA 1 ATOM 3084 C C . PHE A 1 398 ? -41.262 -9.654 18.067 1.00 56.51 ? 398 PHE A C 1 ATOM 3085 O O . PHE A 1 398 ? -42.305 -9.109 17.701 1.00 56.96 ? 398 PHE A O 1 ATOM 3086 C CB . PHE A 1 398 ? -39.602 -11.158 16.998 1.00 56.88 ? 398 PHE A CB 1 ATOM 3087 C CG . PHE A 1 398 ? -38.647 -11.335 15.846 1.00 57.37 ? 398 PHE A CG 1 ATOM 3088 C CD1 . PHE A 1 398 ? -37.334 -11.726 16.057 1.00 57.14 ? 398 PHE A CD1 1 ATOM 3089 C CD2 . PHE A 1 398 ? -39.056 -11.070 14.562 1.00 56.93 ? 398 PHE A CD2 1 ATOM 3090 C CE1 . PHE A 1 398 ? -36.461 -11.861 15.011 1.00 57.14 ? 398 PHE A CE1 1 ATOM 3091 C CE2 . PHE A 1 398 ? -38.183 -11.207 13.507 1.00 58.23 ? 398 PHE A CE2 1 ATOM 3092 C CZ . PHE A 1 398 ? -36.883 -11.606 13.730 1.00 57.77 ? 398 PHE A CZ 1 ATOM 3093 N N . ILE A 1 399 ? -41.104 -10.191 19.258 1.00 56.20 ? 399 ILE A N 1 ATOM 3094 C CA . ILE A 1 399 ? -42.248 -10.327 20.142 1.00 55.94 ? 399 ILE A CA 1 ATOM 3095 C C . ILE A 1 399 ? -42.948 -9.021 20.503 1.00 55.62 ? 399 ILE A C 1 ATOM 3096 O O . ILE A 1 399 ? -44.171 -8.976 20.483 1.00 55.55 ? 399 ILE A O 1 ATOM 3097 C CB . ILE A 1 399 ? -41.915 -11.145 21.388 1.00 55.94 ? 399 ILE A CB 1 ATOM 3098 C CG1 . ILE A 1 399 ? -41.513 -12.552 20.951 1.00 56.21 ? 399 ILE A CG1 1 ATOM 3099 C CG2 . ILE A 1 399 ? -43.123 -11.205 22.296 1.00 55.81 ? 399 ILE A CG2 1 ATOM 3100 C CD1 . ILE A 1 399 ? -40.846 -13.362 21.987 1.00 58.51 ? 399 ILE A CD1 1 ATOM 3101 N N . CYS A 1 400 ? -42.207 -7.957 20.801 1.00 55.34 ? 400 CYS A N 1 ATOM 3102 C CA . CYS A 1 400 ? -42.873 -6.697 21.108 1.00 55.70 ? 400 CYS A CA 1 ATOM 3103 C C . CYS A 1 400 ? -43.516 -6.040 19.909 1.00 55.11 ? 400 CYS A C 1 ATOM 3104 O O . CYS A 1 400 ? -44.703 -5.722 19.951 1.00 55.14 ? 400 CYS A O 1 ATOM 3105 C CB . CYS A 1 400 ? -41.960 -5.726 21.826 1.00 55.89 ? 400 CYS A CB 1 ATOM 3106 S SG . CYS A 1 400 ? -41.468 -6.383 23.432 1.00 59.71 ? 400 CYS A SG 1 ATOM 3107 N N . PRO A 1 401 ? -42.754 -5.849 18.830 1.00 54.52 ? 401 PRO A N 1 ATOM 3108 C CA . PRO A 1 401 ? -43.398 -5.117 17.767 1.00 54.07 ? 401 PRO A CA 1 ATOM 3109 C C . PRO A 1 401 ? -44.583 -5.924 17.291 1.00 54.12 ? 401 PRO A C 1 ATOM 3110 O O . PRO A 1 401 ? -45.579 -5.352 16.835 1.00 53.84 ? 401 PRO A O 1 ATOM 3111 C CB . PRO A 1 401 ? -42.326 -5.029 16.685 1.00 53.90 ? 401 PRO A CB 1 ATOM 3112 C CG . PRO A 1 401 ? -41.064 -5.350 17.356 1.00 54.38 ? 401 PRO A CG 1 ATOM 3113 C CD . PRO A 1 401 ? -41.383 -6.246 18.498 1.00 54.25 ? 401 PRO A CD 1 ATOM 3114 N N . ALA A 1 402 ? -44.483 -7.250 17.398 1.00 54.06 ? 402 ALA A N 1 ATOM 3115 C CA . ALA A 1 402 ? -45.593 -8.130 17.023 1.00 53.91 ? 402 ALA A CA 1 ATOM 3116 C C . ALA A 1 402 ? -46.820 -7.804 17.869 1.00 53.99 ? 402 ALA A C 1 ATOM 3117 O O . ALA A 1 402 ? -47.896 -7.509 17.349 1.00 54.08 ? 402 ALA A O 1 ATOM 3118 C CB . ALA A 1 402 ? -45.205 -9.581 17.200 1.00 53.70 ? 402 ALA A CB 1 ATOM 3119 N N . LEU A 1 403 ? -46.639 -7.841 19.184 1.00 53.90 ? 403 LEU A N 1 ATOM 3120 C CA . LEU A 1 403 ? -47.722 -7.612 20.105 1.00 53.55 ? 403 LEU A CA 1 ATOM 3121 C C . LEU A 1 403 ? -48.325 -6.247 19.881 1.00 54.20 ? 403 LEU A C 1 ATOM 3122 O O . LEU A 1 403 ? -49.509 -6.133 19.650 1.00 54.19 ? 403 LEU A O 1 ATOM 3123 C CB . LEU A 1 403 ? -47.211 -7.734 21.518 1.00 53.03 ? 403 LEU A CB 1 ATOM 3124 C CG . LEU A 1 403 ? -47.184 -9.150 22.053 1.00 51.86 ? 403 LEU A CG 1 ATOM 3125 C CD1 . LEU A 1 403 ? -46.378 -9.210 23.308 1.00 51.96 ? 403 LEU A CD1 1 ATOM 3126 C CD2 . LEU A 1 403 ? -48.578 -9.604 22.333 1.00 51.21 ? 403 LEU A CD2 1 ATOM 3127 N N . GLU A 1 404 ? -47.502 -5.209 19.929 1.00 55.11 ? 404 GLU A N 1 ATOM 3128 C CA . GLU A 1 404 ? -47.954 -3.834 19.671 1.00 56.25 ? 404 GLU A CA 1 ATOM 3129 C C . GLU A 1 404 ? -48.744 -3.622 18.348 1.00 55.99 ? 404 GLU A C 1 ATOM 3130 O O . GLU A 1 404 ? -49.765 -2.954 18.326 1.00 56.18 ? 404 GLU A O 1 ATOM 3131 C CB . GLU A 1 404 ? -46.751 -2.901 19.736 1.00 56.84 ? 404 GLU A CB 1 ATOM 3132 C CG . GLU A 1 404 ? -47.051 -1.441 19.460 1.00 60.99 ? 404 GLU A CG 1 ATOM 3133 C CD . GLU A 1 404 ? -47.586 -0.713 20.685 1.00 65.95 ? 404 GLU A CD 1 ATOM 3134 O OE1 . GLU A 1 404 ? -47.966 -1.382 21.682 1.00 67.91 ? 404 GLU A OE1 1 ATOM 3135 O OE2 . GLU A 1 404 ? -47.625 0.539 20.645 1.00 67.82 ? 404 GLU A OE2 1 ATOM 3136 N N . PHE A 1 405 ? -48.282 -4.183 17.245 1.00 55.80 ? 405 PHE A N 1 ATOM 3137 C CA . PHE A 1 405 ? -49.095 -4.167 16.053 1.00 55.63 ? 405 PHE A CA 1 ATOM 3138 C C . PHE A 1 405 ? -50.492 -4.708 16.338 1.00 55.92 ? 405 PHE A C 1 ATOM 3139 O O . PHE A 1 405 ? -51.488 -4.032 16.108 1.00 56.26 ? 405 PHE A O 1 ATOM 3140 C CB . PHE A 1 405 ? -48.454 -4.998 14.955 1.00 55.55 ? 405 PHE A CB 1 ATOM 3141 C CG . PHE A 1 405 ? -49.292 -5.104 13.716 1.00 54.30 ? 405 PHE A CG 1 ATOM 3142 C CD1 . PHE A 1 405 ? -49.217 -4.146 12.734 1.00 53.51 ? 405 PHE A CD1 1 ATOM 3143 C CD2 . PHE A 1 405 ? -50.156 -6.169 13.535 1.00 54.09 ? 405 PHE A CD2 1 ATOM 3144 C CE1 . PHE A 1 405 ? -49.987 -4.248 11.572 1.00 53.49 ? 405 PHE A CE1 1 ATOM 3145 C CE2 . PHE A 1 405 ? -50.935 -6.284 12.380 1.00 53.50 ? 405 PHE A CE2 1 ATOM 3146 C CZ . PHE A 1 405 ? -50.847 -5.319 11.400 1.00 53.47 ? 405 PHE A CZ 1 ATOM 3147 N N . THR A 1 406 ? -50.571 -5.940 16.817 1.00 56.00 ? 406 THR A N 1 ATOM 3148 C CA . THR A 1 406 ? -51.858 -6.547 17.130 1.00 56.29 ? 406 THR A CA 1 ATOM 3149 C C . THR A 1 406 ? -52.722 -5.582 17.937 1.00 56.86 ? 406 THR A C 1 ATOM 3150 O O . THR A 1 406 ? -53.879 -5.328 17.620 1.00 57.30 ? 406 THR A O 1 ATOM 3151 C CB . THR A 1 406 ? -51.663 -7.831 17.950 1.00 56.02 ? 406 THR A CB 1 ATOM 3152 O OG1 . THR A 1 406 ? -50.622 -8.606 17.361 1.00 56.38 ? 406 THR A OG1 1 ATOM 3153 C CG2 . THR A 1 406 ? -52.928 -8.649 18.003 1.00 55.05 ? 406 THR A CG2 1 ATOM 3154 N N . LYS A 1 407 ? -52.145 -5.038 18.990 1.00 57.27 ? 407 LYS A N 1 ATOM 3155 C CA . LYS A 1 407 ? -52.857 -4.141 19.870 1.00 57.54 ? 407 LYS A CA 1 ATOM 3156 C C . LYS A 1 407 ? -53.466 -2.983 19.100 1.00 57.00 ? 407 LYS A C 1 ATOM 3157 O O . LYS A 1 407 ? -54.662 -2.784 19.107 1.00 56.76 ? 407 LYS A O 1 ATOM 3158 C CB . LYS A 1 407 ? -51.889 -3.625 20.919 1.00 57.93 ? 407 LYS A CB 1 ATOM 3159 C CG . LYS A 1 407 ? -52.522 -3.218 22.195 1.00 60.17 ? 407 LYS A CG 1 ATOM 3160 C CD . LYS A 1 407 ? -51.474 -2.624 23.125 1.00 64.91 ? 407 LYS A CD 1 ATOM 3161 C CE . LYS A 1 407 ? -52.139 -1.821 24.256 1.00 67.48 ? 407 LYS A CE 1 ATOM 3162 N NZ . LYS A 1 407 ? -53.509 -1.311 23.887 1.00 67.97 ? 407 LYS A NZ 1 ATOM 3163 N N . LYS A 1 408 ? -52.644 -2.230 18.408 1.00 57.07 ? 408 LYS A N 1 ATOM 3164 C CA . LYS A 1 408 ? -53.143 -1.037 17.769 1.00 57.92 ? 408 LYS A CA 1 ATOM 3165 C C . LYS A 1 408 ? -54.122 -1.372 16.672 1.00 58.04 ? 408 LYS A C 1 ATOM 3166 O O . LYS A 1 408 ? -54.988 -0.575 16.347 1.00 57.95 ? 408 LYS A O 1 ATOM 3167 C CB . LYS A 1 408 ? -51.999 -0.229 17.176 1.00 58.22 ? 408 LYS A CB 1 ATOM 3168 C CG . LYS A 1 408 ? -50.888 0.041 18.152 1.00 60.17 ? 408 LYS A CG 1 ATOM 3169 C CD . LYS A 1 408 ? -50.918 1.453 18.654 1.00 63.04 ? 408 LYS A CD 1 ATOM 3170 C CE . LYS A 1 408 ? -49.510 2.008 18.525 1.00 65.65 ? 408 LYS A CE 1 ATOM 3171 N NZ . LYS A 1 408 ? -49.322 3.347 19.117 1.00 68.24 ? 408 LYS A NZ 1 ATOM 3172 N N . PHE A 1 409 ? -53.969 -2.542 16.073 1.00 58.50 ? 409 PHE A N 1 ATOM 3173 C CA . PHE A 1 409 ? -54.819 -2.918 14.955 1.00 58.66 ? 409 PHE A CA 1 ATOM 3174 C C . PHE A 1 409 ? -56.228 -3.222 15.451 1.00 59.63 ? 409 PHE A C 1 ATOM 3175 O O . PHE A 1 409 ? -57.220 -2.819 14.848 1.00 59.82 ? 409 PHE A O 1 ATOM 3176 C CB . PHE A 1 409 ? -54.235 -4.131 14.233 1.00 58.11 ? 409 PHE A CB 1 ATOM 3177 C CG . PHE A 1 409 ? -54.962 -4.503 12.956 1.00 55.71 ? 409 PHE A CG 1 ATOM 3178 C CD1 . PHE A 1 409 ? -54.595 -3.949 11.745 1.00 53.01 ? 409 PHE A CD1 1 ATOM 3179 C CD2 . PHE A 1 409 ? -55.990 -5.423 12.975 1.00 53.07 ? 409 PHE A CD2 1 ATOM 3180 C CE1 . PHE A 1 409 ? -55.234 -4.284 10.603 1.00 52.11 ? 409 PHE A CE1 1 ATOM 3181 C CE2 . PHE A 1 409 ? -56.639 -5.766 11.829 1.00 51.96 ? 409 PHE A CE2 1 ATOM 3182 C CZ . PHE A 1 409 ? -56.260 -5.196 10.636 1.00 52.65 ? 409 PHE A CZ 1 ATOM 3183 N N . SER A 1 410 ? -56.312 -3.925 16.567 1.00 60.52 ? 410 SER A N 1 ATOM 3184 C CA . SER A 1 410 ? -57.599 -4.330 17.071 1.00 61.72 ? 410 SER A CA 1 ATOM 3185 C C . SER A 1 410 ? -58.312 -3.125 17.638 1.00 62.69 ? 410 SER A C 1 ATOM 3186 O O . SER A 1 410 ? -59.527 -3.141 17.808 1.00 63.00 ? 410 SER A O 1 ATOM 3187 C CB . SER A 1 410 ? -57.433 -5.361 18.161 1.00 61.52 ? 410 SER A CB 1 ATOM 3188 O OG . SER A 1 410 ? -56.666 -4.795 19.193 1.00 62.15 ? 410 SER A OG 1 ATOM 3189 N N . GLU A 1 411 ? -57.575 -2.069 17.947 1.00 63.74 ? 411 GLU A N 1 ATOM 3190 C CA . GLU A 1 411 ? -58.243 -0.892 18.462 1.00 64.81 ? 411 GLU A CA 1 ATOM 3191 C C . GLU A 1 411 ? -59.216 -0.320 17.439 1.00 65.39 ? 411 GLU A C 1 ATOM 3192 O O . GLU A 1 411 ? -60.167 0.344 17.795 1.00 65.95 ? 411 GLU A O 1 ATOM 3193 C CB . GLU A 1 411 ? -57.243 0.158 18.899 1.00 64.81 ? 411 GLU A CB 1 ATOM 3194 C CG . GLU A 1 411 ? -56.948 0.121 20.360 1.00 66.47 ? 411 GLU A CG 1 ATOM 3195 C CD . GLU A 1 411 ? -55.570 0.645 20.686 1.00 69.40 ? 411 GLU A CD 1 ATOM 3196 O OE1 . GLU A 1 411 ? -55.011 1.441 19.896 1.00 70.47 ? 411 GLU A OE1 1 ATOM 3197 O OE2 . GLU A 1 411 ? -55.028 0.254 21.741 1.00 71.62 ? 411 GLU A OE2 1 ATOM 3198 N N . TRP A 1 412 ? -59.012 -0.584 16.159 1.00 66.01 ? 412 TRP A N 1 ATOM 3199 C CA . TRP A 1 412 ? -59.904 0.008 15.176 1.00 66.40 ? 412 TRP A CA 1 ATOM 3200 C C . TRP A 1 412 ? -61.041 -0.912 14.838 1.00 66.56 ? 412 TRP A C 1 ATOM 3201 O O . TRP A 1 412 ? -61.670 -0.788 13.800 1.00 66.89 ? 412 TRP A O 1 ATOM 3202 C CB . TRP A 1 412 ? -59.143 0.497 13.949 1.00 66.53 ? 412 TRP A CB 1 ATOM 3203 C CG . TRP A 1 412 ? -58.367 1.691 14.325 1.00 67.63 ? 412 TRP A CG 1 ATOM 3204 C CD1 . TRP A 1 412 ? -57.194 1.726 15.031 1.00 68.03 ? 412 TRP A CD1 1 ATOM 3205 C CD2 . TRP A 1 412 ? -58.738 3.041 14.100 1.00 68.98 ? 412 TRP A CD2 1 ATOM 3206 N NE1 . TRP A 1 412 ? -56.801 3.021 15.235 1.00 68.64 ? 412 TRP A NE1 1 ATOM 3207 C CE2 . TRP A 1 412 ? -57.735 3.851 14.672 1.00 69.65 ? 412 TRP A CE2 1 ATOM 3208 C CE3 . TRP A 1 412 ? -59.817 3.652 13.460 1.00 69.08 ? 412 TRP A CE3 1 ATOM 3209 C CZ2 . TRP A 1 412 ? -57.779 5.240 14.614 1.00 69.79 ? 412 TRP A CZ2 1 ATOM 3210 C CZ3 . TRP A 1 412 ? -59.861 5.027 13.403 1.00 69.00 ? 412 TRP A CZ3 1 ATOM 3211 C CH2 . TRP A 1 412 ? -58.846 5.809 13.978 1.00 69.61 ? 412 TRP A CH2 1 ATOM 3212 N N . GLY A 1 413 ? -61.312 -1.831 15.748 1.00 66.67 ? 413 GLY A N 1 ATOM 3213 C CA . GLY A 1 413 ? -62.560 -2.557 15.726 1.00 66.73 ? 413 GLY A CA 1 ATOM 3214 C C . GLY A 1 413 ? -62.537 -3.874 15.001 1.00 66.64 ? 413 GLY A C 1 ATOM 3215 O O . GLY A 1 413 ? -63.577 -4.379 14.622 1.00 67.27 ? 413 GLY A O 1 ATOM 3216 N N . ASN A 1 414 ? -61.367 -4.452 14.807 1.00 66.40 ? 414 ASN A N 1 ATOM 3217 C CA . ASN A 1 414 ? -61.321 -5.716 14.111 1.00 66.05 ? 414 ASN A CA 1 ATOM 3218 C C . ASN A 1 414 ? -60.941 -6.852 15.022 1.00 65.48 ? 414 ASN A C 1 ATOM 3219 O O . ASN A 1 414 ? -60.260 -6.658 16.033 1.00 65.26 ? 414 ASN A O 1 ATOM 3220 C CB . ASN A 1 414 ? -60.343 -5.639 12.963 1.00 66.36 ? 414 ASN A CB 1 ATOM 3221 C CG . ASN A 1 414 ? -60.568 -4.442 12.135 1.00 67.81 ? 414 ASN A CG 1 ATOM 3222 O OD1 . ASN A 1 414 ? -61.393 -4.465 11.219 1.00 69.94 ? 414 ASN A OD1 1 ATOM 3223 N ND2 . ASN A 1 414 ? -59.857 -3.355 12.455 1.00 68.73 ? 414 ASN A ND2 1 ATOM 3224 N N . ASN A 1 415 ? -61.379 -8.045 14.641 1.00 64.77 ? 415 ASN A N 1 ATOM 3225 C CA . ASN A 1 415 ? -61.014 -9.239 15.357 1.00 64.01 ? 415 ASN A CA 1 ATOM 3226 C C . ASN A 1 415 ? -59.599 -9.658 15.047 1.00 63.29 ? 415 ASN A C 1 ATOM 3227 O O . ASN A 1 415 ? -59.201 -9.748 13.877 1.00 63.58 ? 415 ASN A O 1 ATOM 3228 C CB . ASN A 1 415 ? -61.956 -10.364 15.002 1.00 64.43 ? 415 ASN A CB 1 ATOM 3229 C CG . ASN A 1 415 ? -63.262 -10.248 15.714 1.00 65.15 ? 415 ASN A CG 1 ATOM 3230 O OD1 . ASN A 1 415 ? -63.522 -9.259 16.398 1.00 67.15 ? 415 ASN A OD1 1 ATOM 3231 N ND2 . ASN A 1 415 ? -64.101 -11.257 15.568 1.00 66.02 ? 415 ASN A ND2 1 ATOM 3232 N N . ALA A 1 416 ? -58.846 -9.916 16.102 1.00 61.97 ? 416 ALA A N 1 ATOM 3233 C CA . ALA A 1 416 ? -57.486 -10.333 15.968 1.00 60.96 ? 416 ALA A CA 1 ATOM 3234 C C . ALA A 1 416 ? -57.230 -11.481 16.958 1.00 60.57 ? 416 ALA A C 1 ATOM 3235 O O . ALA A 1 416 ? -57.753 -11.499 18.080 1.00 60.61 ? 416 ALA A O 1 ATOM 3236 C CB . ALA A 1 416 ? -56.579 -9.158 16.213 1.00 60.54 ? 416 ALA A CB 1 ATOM 3237 N N . PHE A 1 417 ? -56.461 -12.471 16.532 1.00 59.81 ? 417 PHE A N 1 ATOM 3238 C CA . PHE A 1 417 ? -56.149 -13.577 17.414 1.00 59.27 ? 417 PHE A CA 1 ATOM 3239 C C . PHE A 1 417 ? -54.655 -13.660 17.596 1.00 59.04 ? 417 PHE A C 1 ATOM 3240 O O . PHE A 1 417 ? -53.909 -13.415 16.655 1.00 59.42 ? 417 PHE A O 1 ATOM 3241 C CB . PHE A 1 417 ? -56.700 -14.870 16.823 1.00 58.99 ? 417 PHE A CB 1 ATOM 3242 C CG . PHE A 1 417 ? -58.169 -14.816 16.550 1.00 58.50 ? 417 PHE A CG 1 ATOM 3243 C CD1 . PHE A 1 417 ? -58.646 -14.275 15.366 1.00 57.99 ? 417 PHE A CD1 1 ATOM 3244 C CD2 . PHE A 1 417 ? -59.077 -15.269 17.489 1.00 56.94 ? 417 PHE A CD2 1 ATOM 3245 C CE1 . PHE A 1 417 ? -60.006 -14.212 15.125 1.00 56.83 ? 417 PHE A CE1 1 ATOM 3246 C CE2 . PHE A 1 417 ? -60.419 -15.215 17.252 1.00 55.92 ? 417 PHE A CE2 1 ATOM 3247 C CZ . PHE A 1 417 ? -60.888 -14.690 16.078 1.00 56.58 ? 417 PHE A CZ 1 ATOM 3248 N N . PHE A 1 418 ? -54.199 -14.004 18.789 1.00 58.42 ? 418 PHE A N 1 ATOM 3249 C CA . PHE A 1 418 ? -52.766 -14.055 19.006 1.00 58.27 ? 418 PHE A CA 1 ATOM 3250 C C . PHE A 1 418 ? -52.302 -15.393 19.557 1.00 58.71 ? 418 PHE A C 1 ATOM 3251 O O . PHE A 1 418 ? -52.938 -15.953 20.444 1.00 59.08 ? 418 PHE A O 1 ATOM 3252 C CB . PHE A 1 418 ? -52.332 -12.920 19.923 1.00 58.04 ? 418 PHE A CB 1 ATOM 3253 C CG . PHE A 1 418 ? -50.904 -12.538 19.762 1.00 57.62 ? 418 PHE A CG 1 ATOM 3254 C CD1 . PHE A 1 418 ? -49.909 -13.228 20.445 1.00 57.85 ? 418 PHE A CD1 1 ATOM 3255 C CD2 . PHE A 1 418 ? -50.539 -11.504 18.911 1.00 56.24 ? 418 PHE A CD2 1 ATOM 3256 C CE1 . PHE A 1 418 ? -48.571 -12.885 20.280 1.00 57.40 ? 418 PHE A CE1 1 ATOM 3257 C CE2 . PHE A 1 418 ? -49.203 -11.150 18.745 1.00 55.07 ? 418 PHE A CE2 1 ATOM 3258 C CZ . PHE A 1 418 ? -48.223 -11.836 19.426 1.00 56.20 ? 418 PHE A CZ 1 ATOM 3259 N N . TYR A 1 419 ? -51.198 -15.913 19.018 1.00 59.11 ? 419 TYR A N 1 ATOM 3260 C CA . TYR A 1 419 ? -50.649 -17.202 19.453 1.00 59.37 ? 419 TYR A CA 1 ATOM 3261 C C . TYR A 1 419 ? -49.216 -17.075 19.923 1.00 60.30 ? 419 TYR A C 1 ATOM 3262 O O . TYR A 1 419 ? -48.455 -16.246 19.433 1.00 60.67 ? 419 TYR A O 1 ATOM 3263 C CB . TYR A 1 419 ? -50.701 -18.234 18.332 1.00 59.03 ? 419 TYR A CB 1 ATOM 3264 C CG . TYR A 1 419 ? -49.724 -18.008 17.175 1.00 58.02 ? 419 TYR A CG 1 ATOM 3265 C CD1 . TYR A 1 419 ? -50.127 -17.393 16.019 1.00 56.26 ? 419 TYR A CD1 1 ATOM 3266 C CD2 . TYR A 1 419 ? -48.409 -18.434 17.249 1.00 56.39 ? 419 TYR A CD2 1 ATOM 3267 C CE1 . TYR A 1 419 ? -49.261 -17.212 14.982 1.00 56.11 ? 419 TYR A CE1 1 ATOM 3268 C CE2 . TYR A 1 419 ? -47.542 -18.249 16.222 1.00 54.40 ? 419 TYR A CE2 1 ATOM 3269 C CZ . TYR A 1 419 ? -47.964 -17.641 15.083 1.00 55.71 ? 419 TYR A CZ 1 ATOM 3270 O OH . TYR A 1 419 ? -47.092 -17.444 14.023 1.00 55.47 ? 419 TYR A OH 1 ATOM 3271 N N . TYR A 1 420 ? -48.853 -17.907 20.882 1.00 61.17 ? 420 TYR A N 1 ATOM 3272 C CA . TYR A 1 420 ? -47.499 -17.980 21.368 1.00 62.02 ? 420 TYR A CA 1 ATOM 3273 C C . TYR A 1 420 ? -47.101 -19.427 21.172 1.00 63.19 ? 420 TYR A C 1 ATOM 3274 O O . TYR A 1 420 ? -47.498 -20.308 21.939 1.00 63.23 ? 420 TYR A O 1 ATOM 3275 C CB . TYR A 1 420 ? -47.459 -17.591 22.837 1.00 61.78 ? 420 TYR A CB 1 ATOM 3276 C CG . TYR A 1 420 ? -46.083 -17.534 23.496 1.00 61.37 ? 420 TYR A CG 1 ATOM 3277 C CD1 . TYR A 1 420 ? -45.099 -16.659 23.050 1.00 60.16 ? 420 TYR A CD1 1 ATOM 3278 C CD2 . TYR A 1 420 ? -45.797 -18.315 24.620 1.00 60.86 ? 420 TYR A CD2 1 ATOM 3279 C CE1 . TYR A 1 420 ? -43.865 -16.598 23.687 1.00 59.52 ? 420 TYR A CE1 1 ATOM 3280 C CE2 . TYR A 1 420 ? -44.578 -18.257 25.247 1.00 59.52 ? 420 TYR A CE2 1 ATOM 3281 C CZ . TYR A 1 420 ? -43.621 -17.405 24.779 1.00 59.17 ? 420 TYR A CZ 1 ATOM 3282 O OH . TYR A 1 420 ? -42.411 -17.362 25.408 1.00 59.29 ? 420 TYR A OH 1 ATOM 3283 N N . PHE A 1 421 ? -46.341 -19.663 20.105 1.00 64.52 ? 421 PHE A N 1 ATOM 3284 C CA . PHE A 1 421 ? -45.919 -20.990 19.704 1.00 65.79 ? 421 PHE A CA 1 ATOM 3285 C C . PHE A 1 421 ? -44.726 -21.416 20.509 1.00 66.22 ? 421 PHE A C 1 ATOM 3286 O O . PHE A 1 421 ? -43.688 -20.778 20.469 1.00 66.24 ? 421 PHE A O 1 ATOM 3287 C CB . PHE A 1 421 ? -45.543 -20.971 18.238 1.00 66.27 ? 421 PHE A CB 1 ATOM 3288 C CG . PHE A 1 421 ? -45.133 -22.296 17.715 1.00 68.24 ? 421 PHE A CG 1 ATOM 3289 C CD1 . PHE A 1 421 ? -46.073 -23.156 17.183 1.00 69.16 ? 421 PHE A CD1 1 ATOM 3290 C CD2 . PHE A 1 421 ? -43.801 -22.692 17.764 1.00 70.41 ? 421 PHE A CD2 1 ATOM 3291 C CE1 . PHE A 1 421 ? -45.701 -24.395 16.698 1.00 70.50 ? 421 PHE A CE1 1 ATOM 3292 C CE2 . PHE A 1 421 ? -43.420 -23.928 17.283 1.00 71.59 ? 421 PHE A CE2 1 ATOM 3293 C CZ . PHE A 1 421 ? -44.375 -24.782 16.741 1.00 71.42 ? 421 PHE A CZ 1 ATOM 3294 N N . GLU A 1 422 ? -44.863 -22.506 21.237 1.00 67.08 ? 422 GLU A N 1 ATOM 3295 C CA . GLU A 1 422 ? -43.829 -22.871 22.184 1.00 68.28 ? 422 GLU A CA 1 ATOM 3296 C C . GLU A 1 422 ? -43.471 -24.341 22.147 1.00 68.79 ? 422 GLU A C 1 ATOM 3297 O O . GLU A 1 422 ? -43.273 -24.971 23.172 1.00 68.57 ? 422 GLU A O 1 ATOM 3298 C CB . GLU A 1 422 ? -44.229 -22.459 23.598 1.00 68.41 ? 422 GLU A CB 1 ATOM 3299 C CG . GLU A 1 422 ? -45.467 -23.121 24.096 1.00 69.59 ? 422 GLU A CG 1 ATOM 3300 C CD . GLU A 1 422 ? -45.946 -22.499 25.352 1.00 71.16 ? 422 GLU A CD 1 ATOM 3301 O OE1 . GLU A 1 422 ? -45.397 -21.443 25.718 1.00 71.21 ? 422 GLU A OE1 1 ATOM 3302 O OE2 . GLU A 1 422 ? -46.871 -23.065 25.970 1.00 73.45 ? 422 GLU A OE2 1 ATOM 3303 N N . HIS A 1 423 ? -43.376 -24.888 20.949 1.00 69.93 ? 423 HIS A N 1 ATOM 3304 C CA . HIS A 1 423 ? -42.960 -26.265 20.814 1.00 70.74 ? 423 HIS A CA 1 ATOM 3305 C C . HIS A 1 423 ? -41.685 -26.419 19.976 1.00 71.30 ? 423 HIS A C 1 ATOM 3306 O O . HIS A 1 423 ? -41.565 -25.850 18.884 1.00 70.96 ? 423 HIS A O 1 ATOM 3307 C CB . HIS A 1 423 ? -44.082 -27.133 20.259 1.00 70.66 ? 423 HIS A CB 1 ATOM 3308 C CG . HIS A 1 423 ? -43.685 -28.557 20.134 1.00 71.76 ? 423 HIS A CG 1 ATOM 3309 N ND1 . HIS A 1 423 ? -43.718 -29.428 21.199 1.00 72.61 ? 423 HIS A ND1 1 ATOM 3310 C CD2 . HIS A 1 423 ? -43.156 -29.244 19.095 1.00 72.49 ? 423 HIS A CD2 1 ATOM 3311 C CE1 . HIS A 1 423 ? -43.259 -30.603 20.811 1.00 73.33 ? 423 HIS A CE1 1 ATOM 3312 N NE2 . HIS A 1 423 ? -42.910 -30.517 19.539 1.00 73.53 ? 423 HIS A NE2 1 ATOM 3313 N N . ARG A 1 424 ? -40.735 -27.191 20.511 1.00 72.17 ? 424 ARG A N 1 ATOM 3314 C CA . ARG A 1 424 ? -39.458 -27.459 19.853 1.00 72.97 ? 424 ARG A CA 1 ATOM 3315 C C . ARG A 1 424 ? -39.526 -28.743 19.052 1.00 73.13 ? 424 ARG A C 1 ATOM 3316 O O . ARG A 1 424 ? -39.601 -29.822 19.621 1.00 73.46 ? 424 ARG A O 1 ATOM 3317 C CB . ARG A 1 424 ? -38.350 -27.580 20.899 1.00 73.27 ? 424 ARG A CB 1 ATOM 3318 C CG . ARG A 1 424 ? -36.967 -27.906 20.338 1.00 75.13 ? 424 ARG A CG 1 ATOM 3319 C CD . ARG A 1 424 ? -35.885 -27.866 21.436 1.00 78.16 ? 424 ARG A CD 1 ATOM 3320 N NE . ARG A 1 424 ? -34.600 -28.404 20.985 1.00 79.43 ? 424 ARG A NE 1 ATOM 3321 C CZ . ARG A 1 424 ? -33.739 -27.750 20.212 1.00 79.81 ? 424 ARG A CZ 1 ATOM 3322 N NH1 . ARG A 1 424 ? -34.006 -26.529 19.784 1.00 80.19 ? 424 ARG A NH1 1 ATOM 3323 N NH2 . ARG A 1 424 ? -32.606 -28.320 19.862 1.00 80.15 ? 424 ARG A NH2 1 ATOM 3324 N N . SER A 1 425 ? -39.516 -28.627 17.731 1.00 73.30 ? 425 SER A N 1 ATOM 3325 C CA . SER A 1 425 ? -39.500 -29.799 16.872 1.00 73.44 ? 425 SER A CA 1 ATOM 3326 C C . SER A 1 425 ? -38.469 -30.767 17.393 1.00 73.55 ? 425 SER A C 1 ATOM 3327 O O . SER A 1 425 ? -37.372 -30.354 17.725 1.00 73.71 ? 425 SER A O 1 ATOM 3328 C CB . SER A 1 425 ? -39.136 -29.387 15.460 1.00 73.49 ? 425 SER A CB 1 ATOM 3329 O OG . SER A 1 425 ? -38.432 -30.409 14.786 1.00 74.22 ? 425 SER A OG 1 ATOM 3330 N N . SER A 1 426 ? -38.806 -32.053 17.473 1.00 73.75 ? 426 SER A N 1 ATOM 3331 C CA . SER A 1 426 ? -37.855 -33.053 17.994 1.00 74.05 ? 426 SER A CA 1 ATOM 3332 C C . SER A 1 426 ? -36.831 -33.476 16.945 1.00 74.07 ? 426 SER A C 1 ATOM 3333 O O . SER A 1 426 ? -35.936 -34.274 17.215 1.00 74.03 ? 426 SER A O 1 ATOM 3334 C CB . SER A 1 426 ? -38.587 -34.281 18.524 1.00 74.18 ? 426 SER A CB 1 ATOM 3335 O OG . SER A 1 426 ? -39.568 -34.714 17.596 1.00 74.68 ? 426 SER A OG 1 ATOM 3336 N N . LYS A 1 427 ? -36.984 -32.929 15.748 1.00 74.04 ? 427 LYS A N 1 ATOM 3337 C CA . LYS A 1 427 ? -36.058 -33.136 14.675 1.00 74.04 ? 427 LYS A CA 1 ATOM 3338 C C . LYS A 1 427 ? -35.267 -31.860 14.460 1.00 73.71 ? 427 LYS A C 1 ATOM 3339 O O . LYS A 1 427 ? -34.780 -31.616 13.362 1.00 74.40 ? 427 LYS A O 1 ATOM 3340 C CB . LYS A 1 427 ? -36.841 -33.432 13.402 1.00 74.46 ? 427 LYS A CB 1 ATOM 3341 C CG . LYS A 1 427 ? -37.157 -34.906 13.152 1.00 76.45 ? 427 LYS A CG 1 ATOM 3342 C CD . LYS A 1 427 ? -38.153 -35.098 11.983 1.00 79.76 ? 427 LYS A CD 1 ATOM 3343 C CE . LYS A 1 427 ? -38.042 -33.988 10.900 1.00 81.14 ? 427 LYS A CE 1 ATOM 3344 N NZ . LYS A 1 427 ? -37.243 -34.313 9.681 1.00 81.82 ? 427 LYS A NZ 1 ATOM 3345 N N . LEU A 1 428 ? -35.147 -31.026 15.486 1.00 72.81 ? 428 LEU A N 1 ATOM 3346 C CA . LEU A 1 428 ? -34.512 -29.711 15.322 1.00 71.75 ? 428 LEU A CA 1 ATOM 3347 C C . LEU A 1 428 ? -32.985 -29.822 15.356 1.00 70.97 ? 428 LEU A C 1 ATOM 3348 O O . LEU A 1 428 ? -32.391 -30.221 16.363 1.00 70.91 ? 428 LEU A O 1 ATOM 3349 C CB . LEU A 1 428 ? -35.042 -28.731 16.378 1.00 71.91 ? 428 LEU A CB 1 ATOM 3350 C CG . LEU A 1 428 ? -35.081 -27.192 16.253 1.00 71.88 ? 428 LEU A CG 1 ATOM 3351 C CD1 . LEU A 1 428 ? -33.756 -26.571 16.689 1.00 72.80 ? 428 LEU A CD1 1 ATOM 3352 C CD2 . LEU A 1 428 ? -35.507 -26.657 14.894 1.00 70.65 ? 428 LEU A CD2 1 ATOM 3353 N N . PRO A 1 429 ? -32.340 -29.478 14.242 1.00 70.06 ? 429 PRO A N 1 ATOM 3354 C CA . PRO A 1 429 ? -30.906 -29.705 14.118 1.00 69.41 ? 429 PRO A CA 1 ATOM 3355 C C . PRO A 1 429 ? -30.059 -28.841 15.042 1.00 68.70 ? 429 PRO A C 1 ATOM 3356 O O . PRO A 1 429 ? -28.914 -29.189 15.298 1.00 68.83 ? 429 PRO A O 1 ATOM 3357 C CB . PRO A 1 429 ? -30.615 -29.396 12.640 1.00 69.52 ? 429 PRO A CB 1 ATOM 3358 C CG . PRO A 1 429 ? -31.769 -28.590 12.163 1.00 69.90 ? 429 PRO A CG 1 ATOM 3359 C CD . PRO A 1 429 ? -32.953 -29.003 12.992 1.00 70.04 ? 429 PRO A CD 1 ATOM 3360 N N . TRP A 1 430 ? -30.600 -27.733 15.539 1.00 67.85 ? 430 TRP A N 1 ATOM 3361 C CA . TRP A 1 430 ? -29.841 -26.877 16.454 1.00 66.91 ? 430 TRP A CA 1 ATOM 3362 C C . TRP A 1 430 ? -29.945 -27.387 17.873 1.00 66.82 ? 430 TRP A C 1 ATOM 3363 O O . TRP A 1 430 ? -30.794 -28.214 18.156 1.00 66.59 ? 430 TRP A O 1 ATOM 3364 C CB . TRP A 1 430 ? -30.343 -25.449 16.423 1.00 66.55 ? 430 TRP A CB 1 ATOM 3365 C CG . TRP A 1 430 ? -30.515 -24.832 15.059 1.00 64.70 ? 430 TRP A CG 1 ATOM 3366 C CD1 . TRP A 1 430 ? -31.604 -24.931 14.251 1.00 62.42 ? 430 TRP A CD1 1 ATOM 3367 C CD2 . TRP A 1 430 ? -29.596 -23.962 14.389 1.00 62.33 ? 430 TRP A CD2 1 ATOM 3368 N NE1 . TRP A 1 430 ? -31.414 -24.194 13.120 1.00 61.34 ? 430 TRP A NE1 1 ATOM 3369 C CE2 . TRP A 1 430 ? -30.186 -23.591 13.179 1.00 61.34 ? 430 TRP A CE2 1 ATOM 3370 C CE3 . TRP A 1 430 ? -28.328 -23.472 14.695 1.00 62.08 ? 430 TRP A CE3 1 ATOM 3371 C CZ2 . TRP A 1 430 ? -29.551 -22.752 12.269 1.00 61.04 ? 430 TRP A CZ2 1 ATOM 3372 C CZ3 . TRP A 1 430 ? -27.698 -22.647 13.784 1.00 61.36 ? 430 TRP A CZ3 1 ATOM 3373 C CH2 . TRP A 1 430 ? -28.311 -22.291 12.591 1.00 60.54 ? 430 TRP A CH2 1 ATOM 3374 N N . PRO A 1 431 ? -29.077 -26.888 18.767 1.00 66.85 ? 431 PRO A N 1 ATOM 3375 C CA . PRO A 1 431 ? -28.945 -27.381 20.137 1.00 67.08 ? 431 PRO A CA 1 ATOM 3376 C C . PRO A 1 431 ? -30.119 -27.031 21.062 1.00 67.36 ? 431 PRO A C 1 ATOM 3377 O O . PRO A 1 431 ? -30.867 -26.091 20.799 1.00 67.53 ? 431 PRO A O 1 ATOM 3378 C CB . PRO A 1 431 ? -27.650 -26.727 20.624 1.00 66.77 ? 431 PRO A CB 1 ATOM 3379 C CG . PRO A 1 431 ? -27.478 -25.557 19.791 1.00 66.75 ? 431 PRO A CG 1 ATOM 3380 C CD . PRO A 1 431 ? -28.076 -25.860 18.457 1.00 66.87 ? 431 PRO A CD 1 ATOM 3381 N N . GLU A 1 432 ? -30.279 -27.797 22.138 1.00 67.58 ? 432 GLU A N 1 ATOM 3382 C CA . GLU A 1 432 ? -31.373 -27.580 23.082 1.00 67.87 ? 432 GLU A CA 1 ATOM 3383 C C . GLU A 1 432 ? -31.511 -26.091 23.437 1.00 67.85 ? 432 GLU A C 1 ATOM 3384 O O . GLU A 1 432 ? -32.594 -25.500 23.315 1.00 68.06 ? 432 GLU A O 1 ATOM 3385 C CB . GLU A 1 432 ? -31.163 -28.415 24.355 1.00 67.91 ? 432 GLU A CB 1 ATOM 3386 C CG . GLU A 1 432 ? -30.756 -29.877 24.100 0.50 68.28 ? 432 GLU A CG 1 ATOM 3387 C CD . GLU A 1 432 ? -31.925 -30.838 24.195 0.50 68.82 ? 432 GLU A CD 1 ATOM 3388 O OE1 . GLU A 1 432 ? -32.157 -31.588 23.220 0.50 68.37 ? 432 GLU A OE1 1 ATOM 3389 O OE2 . GLU A 1 432 ? -32.608 -30.841 25.246 0.50 69.21 ? 432 GLU A OE2 1 ATOM 3390 N N . TRP A 1 433 ? -30.407 -25.476 23.844 1.00 67.42 ? 433 TRP A N 1 ATOM 3391 C CA . TRP A 1 433 ? -30.481 -24.130 24.382 1.00 67.06 ? 433 TRP A CA 1 ATOM 3392 C C . TRP A 1 433 ? -31.138 -23.099 23.458 1.00 66.62 ? 433 TRP A C 1 ATOM 3393 O O . TRP A 1 433 ? -31.682 -22.118 23.934 1.00 67.02 ? 433 TRP A O 1 ATOM 3394 C CB . TRP A 1 433 ? -29.121 -23.646 24.901 1.00 67.07 ? 433 TRP A CB 1 ATOM 3395 C CG . TRP A 1 433 ? -28.117 -23.295 23.860 1.00 67.39 ? 433 TRP A CG 1 ATOM 3396 C CD1 . TRP A 1 433 ? -27.080 -24.066 23.436 1.00 68.06 ? 433 TRP A CD1 1 ATOM 3397 C CD2 . TRP A 1 433 ? -28.034 -22.071 23.126 1.00 67.80 ? 433 TRP A CD2 1 ATOM 3398 N NE1 . TRP A 1 433 ? -26.359 -23.405 22.468 1.00 68.77 ? 433 TRP A NE1 1 ATOM 3399 C CE2 . TRP A 1 433 ? -26.928 -22.177 22.257 1.00 68.71 ? 433 TRP A CE2 1 ATOM 3400 C CE3 . TRP A 1 433 ? -28.792 -20.908 23.104 1.00 67.22 ? 433 TRP A CE3 1 ATOM 3401 C CZ2 . TRP A 1 433 ? -26.562 -21.155 21.377 1.00 68.73 ? 433 TRP A CZ2 1 ATOM 3402 C CZ3 . TRP A 1 433 ? -28.421 -19.898 22.231 1.00 68.65 ? 433 TRP A CZ3 1 ATOM 3403 C CH2 . TRP A 1 433 ? -27.317 -20.025 21.382 1.00 68.28 ? 433 TRP A CH2 1 ATOM 3404 N N . MET A 1 434 ? -31.114 -23.301 22.150 1.00 65.72 ? 434 MET A N 1 ATOM 3405 C CA . MET A 1 434 ? -31.714 -22.290 21.294 1.00 64.65 ? 434 MET A CA 1 ATOM 3406 C C . MET A 1 434 ? -33.235 -22.343 21.368 1.00 63.86 ? 434 MET A C 1 ATOM 3407 O O . MET A 1 434 ? -33.916 -21.461 20.837 1.00 63.28 ? 434 MET A O 1 ATOM 3408 C CB . MET A 1 434 ? -31.208 -22.412 19.866 1.00 64.86 ? 434 MET A CB 1 ATOM 3409 C CG . MET A 1 434 ? -29.786 -21.962 19.736 1.00 65.55 ? 434 MET A CG 1 ATOM 3410 S SD . MET A 1 434 ? -28.987 -22.300 18.163 1.00 68.96 ? 434 MET A SD 1 ATOM 3411 C CE . MET A 1 434 ? -29.514 -20.930 17.152 1.00 67.68 ? 434 MET A CE 1 ATOM 3412 N N . GLY A 1 435 ? -33.748 -23.384 22.036 1.00 63.00 ? 435 GLY A N 1 ATOM 3413 C CA . GLY A 1 435 ? -35.189 -23.569 22.273 1.00 61.88 ? 435 GLY A CA 1 ATOM 3414 C C . GLY A 1 435 ? -36.120 -23.456 21.071 1.00 61.25 ? 435 GLY A C 1 ATOM 3415 O O . GLY A 1 435 ? -35.736 -23.745 19.944 1.00 61.59 ? 435 GLY A O 1 ATOM 3416 N N . VAL A 1 436 ? -37.365 -23.051 21.310 1.00 60.09 ? 436 VAL A N 1 ATOM 3417 C CA . VAL A 1 436 ? -38.336 -22.847 20.230 1.00 58.66 ? 436 VAL A CA 1 ATOM 3418 C C . VAL A 1 436 ? -37.905 -21.722 19.279 1.00 57.92 ? 436 VAL A C 1 ATOM 3419 O O . VAL A 1 436 ? -38.267 -20.578 19.474 1.00 57.56 ? 436 VAL A O 1 ATOM 3420 C CB . VAL A 1 436 ? -39.701 -22.534 20.841 1.00 58.49 ? 436 VAL A CB 1 ATOM 3421 C CG1 . VAL A 1 436 ? -40.807 -22.517 19.779 1.00 58.76 ? 436 VAL A CG1 1 ATOM 3422 C CG2 . VAL A 1 436 ? -40.008 -23.549 21.905 1.00 57.81 ? 436 VAL A CG2 1 ATOM 3423 N N . MET A 1 437 ? -37.146 -22.052 18.243 1.00 57.36 ? 437 MET A N 1 ATOM 3424 C CA . MET A 1 437 ? -36.448 -21.030 17.449 1.00 57.34 ? 437 MET A CA 1 ATOM 3425 C C . MET A 1 437 ? -37.244 -20.226 16.437 1.00 56.99 ? 437 MET A C 1 ATOM 3426 O O . MET A 1 437 ? -38.324 -20.602 16.005 1.00 56.46 ? 437 MET A O 1 ATOM 3427 C CB . MET A 1 437 ? -35.251 -21.628 16.725 1.00 57.43 ? 437 MET A CB 1 ATOM 3428 C CG . MET A 1 437 ? -34.047 -21.788 17.597 1.00 58.65 ? 437 MET A CG 1 ATOM 3429 S SD . MET A 1 437 ? -32.766 -22.715 16.776 1.00 59.30 ? 437 MET A SD 1 ATOM 3430 C CE . MET A 1 437 ? -32.633 -21.790 15.236 1.00 60.83 ? 437 MET A CE 1 ATOM 3431 N N . HIS A 1 438 ? -36.663 -19.111 16.042 1.00 57.00 ? 438 HIS A N 1 ATOM 3432 C CA . HIS A 1 438 ? -37.262 -18.284 15.024 1.00 57.50 ? 438 HIS A CA 1 ATOM 3433 C C . HIS A 1 438 ? -37.449 -19.164 13.805 1.00 57.78 ? 438 HIS A C 1 ATOM 3434 O O . HIS A 1 438 ? -36.585 -19.984 13.534 1.00 58.03 ? 438 HIS A O 1 ATOM 3435 C CB . HIS A 1 438 ? -36.341 -17.110 14.692 1.00 57.24 ? 438 HIS A CB 1 ATOM 3436 C CG . HIS A 1 438 ? -36.822 -16.259 13.560 1.00 56.93 ? 438 HIS A CG 1 ATOM 3437 N ND1 . HIS A 1 438 ? -38.051 -15.641 13.567 1.00 56.40 ? 438 HIS A ND1 1 ATOM 3438 C CD2 . HIS A 1 438 ? -36.225 -15.901 12.399 1.00 56.92 ? 438 HIS A CD2 1 ATOM 3439 C CE1 . HIS A 1 438 ? -38.199 -14.949 12.452 1.00 56.50 ? 438 HIS A CE1 1 ATOM 3440 N NE2 . HIS A 1 438 ? -37.102 -15.084 11.729 1.00 56.36 ? 438 HIS A NE2 1 ATOM 3441 N N . GLY A 1 439 ? -38.575 -19.004 13.101 1.00 57.85 ? 439 GLY A N 1 ATOM 3442 C CA . GLY A 1 439 ? -38.860 -19.726 11.867 1.00 57.84 ? 439 GLY A CA 1 ATOM 3443 C C . GLY A 1 439 ? -39.191 -21.202 11.983 1.00 58.09 ? 439 GLY A C 1 ATOM 3444 O O . GLY A 1 439 ? -39.458 -21.854 10.991 1.00 57.55 ? 439 GLY A O 1 ATOM 3445 N N . TYR A 1 440 ? -39.180 -21.744 13.193 1.00 58.83 ? 440 TYR A N 1 ATOM 3446 C CA . TYR A 1 440 ? -39.352 -23.187 13.346 1.00 59.55 ? 440 TYR A CA 1 ATOM 3447 C C . TYR A 1 440 ? -40.767 -23.645 13.693 1.00 59.78 ? 440 TYR A C 1 ATOM 3448 O O . TYR A 1 440 ? -40.970 -24.727 14.271 1.00 59.62 ? 440 TYR A O 1 ATOM 3449 C CB . TYR A 1 440 ? -38.270 -23.807 14.246 1.00 59.70 ? 440 TYR A CB 1 ATOM 3450 C CG . TYR A 1 440 ? -36.992 -23.991 13.460 1.00 61.47 ? 440 TYR A CG 1 ATOM 3451 C CD1 . TYR A 1 440 ? -35.909 -23.147 13.636 1.00 62.46 ? 440 TYR A CD1 1 ATOM 3452 C CD2 . TYR A 1 440 ? -36.905 -24.967 12.472 1.00 62.70 ? 440 TYR A CD2 1 ATOM 3453 C CE1 . TYR A 1 440 ? -34.764 -23.307 12.874 1.00 63.50 ? 440 TYR A CE1 1 ATOM 3454 C CE2 . TYR A 1 440 ? -35.771 -25.123 11.713 1.00 63.02 ? 440 TYR A CE2 1 ATOM 3455 C CZ . TYR A 1 440 ? -34.709 -24.296 11.912 1.00 63.52 ? 440 TYR A CZ 1 ATOM 3456 O OH . TYR A 1 440 ? -33.585 -24.466 11.143 1.00 64.03 ? 440 TYR A OH 1 ATOM 3457 N N . GLU A 1 441 ? -41.737 -22.822 13.293 1.00 59.98 ? 441 GLU A N 1 ATOM 3458 C CA . GLU A 1 441 ? -43.144 -23.183 13.363 1.00 60.26 ? 441 GLU A CA 1 ATOM 3459 C C . GLU A 1 441 ? -43.669 -23.345 11.934 1.00 59.86 ? 441 GLU A C 1 ATOM 3460 O O . GLU A 1 441 ? -44.672 -23.991 11.679 1.00 59.63 ? 441 GLU A O 1 ATOM 3461 C CB . GLU A 1 441 ? -43.936 -22.107 14.107 1.00 60.57 ? 441 GLU A CB 1 ATOM 3462 C CG . GLU A 1 441 ? -44.501 -21.008 13.198 1.00 62.46 ? 441 GLU A CG 1 ATOM 3463 C CD . GLU A 1 441 ? -43.434 -20.075 12.645 1.00 64.92 ? 441 GLU A CD 1 ATOM 3464 O OE1 . GLU A 1 441 ? -42.317 -20.043 13.206 1.00 65.92 ? 441 GLU A OE1 1 ATOM 3465 O OE2 . GLU A 1 441 ? -43.718 -19.362 11.657 1.00 64.96 ? 441 GLU A OE2 1 ATOM 3466 N N . ILE A 1 442 ? -42.960 -22.769 10.991 1.00 59.75 ? 442 ILE A N 1 ATOM 3467 C CA . ILE A 1 442 ? -43.372 -22.879 9.613 1.00 59.95 ? 442 ILE A CA 1 ATOM 3468 C C . ILE A 1 442 ? -43.702 -24.314 9.216 1.00 60.34 ? 442 ILE A C 1 ATOM 3469 O O . ILE A 1 442 ? -44.732 -24.569 8.601 1.00 60.48 ? 442 ILE A O 1 ATOM 3470 C CB . ILE A 1 442 ? -42.308 -22.322 8.656 1.00 59.75 ? 442 ILE A CB 1 ATOM 3471 C CG1 . ILE A 1 442 ? -41.958 -20.884 9.024 1.00 59.15 ? 442 ILE A CG1 1 ATOM 3472 C CG2 . ILE A 1 442 ? -42.814 -22.380 7.252 1.00 59.54 ? 442 ILE A CG2 1 ATOM 3473 C CD1 . ILE A 1 442 ? -41.010 -20.264 8.098 1.00 57.89 ? 442 ILE A CD1 1 ATOM 3474 N N . GLU A 1 443 ? -42.826 -25.251 9.557 1.00 60.82 ? 443 GLU A N 1 ATOM 3475 C CA . GLU A 1 443 ? -43.012 -26.629 9.147 1.00 61.02 ? 443 GLU A CA 1 ATOM 3476 C C . GLU A 1 443 ? -44.314 -27.179 9.720 1.00 61.00 ? 443 GLU A C 1 ATOM 3477 O O . GLU A 1 443 ? -45.034 -27.889 9.023 1.00 61.15 ? 443 GLU A O 1 ATOM 3478 C CB . GLU A 1 443 ? -41.804 -27.480 9.526 1.00 61.12 ? 443 GLU A CB 1 ATOM 3479 C CG . GLU A 1 443 ? -41.552 -27.582 11.023 1.00 63.50 ? 443 GLU A CG 1 ATOM 3480 C CD . GLU A 1 443 ? -40.134 -28.039 11.370 1.00 66.40 ? 443 GLU A CD 1 ATOM 3481 O OE1 . GLU A 1 443 ? -39.174 -27.439 10.849 1.00 68.64 ? 443 GLU A OE1 1 ATOM 3482 O OE2 . GLU A 1 443 ? -39.968 -28.987 12.173 1.00 66.04 ? 443 GLU A OE2 1 ATOM 3483 N N . PHE A 1 444 ? -44.643 -26.827 10.966 1.00 60.84 ? 444 PHE A N 1 ATOM 3484 C CA . PHE A 1 444 ? -45.923 -27.230 11.553 1.00 60.58 ? 444 PHE A CA 1 ATOM 3485 C C . PHE A 1 444 ? -47.128 -26.569 10.926 1.00 60.63 ? 444 PHE A C 1 ATOM 3486 O O . PHE A 1 444 ? -48.208 -27.135 10.944 1.00 60.74 ? 444 PHE A O 1 ATOM 3487 C CB . PHE A 1 444 ? -45.981 -26.911 13.015 1.00 60.28 ? 444 PHE A CB 1 ATOM 3488 C CG . PHE A 1 444 ? -45.221 -27.848 13.857 1.00 60.96 ? 444 PHE A CG 1 ATOM 3489 C CD1 . PHE A 1 444 ? -43.841 -27.861 13.806 1.00 61.58 ? 444 PHE A CD1 1 ATOM 3490 C CD2 . PHE A 1 444 ? -45.878 -28.706 14.747 1.00 61.57 ? 444 PHE A CD2 1 ATOM 3491 C CE1 . PHE A 1 444 ? -43.115 -28.720 14.640 1.00 62.61 ? 444 PHE A CE1 1 ATOM 3492 C CE2 . PHE A 1 444 ? -45.167 -29.574 15.585 1.00 61.56 ? 444 PHE A CE2 1 ATOM 3493 C CZ . PHE A 1 444 ? -43.788 -29.584 15.534 1.00 62.39 ? 444 PHE A CZ 1 ATOM 3494 N N . VAL A 1 445 ? -46.965 -25.363 10.409 1.00 60.67 ? 445 VAL A N 1 ATOM 3495 C CA . VAL A 1 445 ? -48.070 -24.724 9.739 1.00 60.88 ? 445 VAL A CA 1 ATOM 3496 C C . VAL A 1 445 ? -48.356 -25.396 8.405 1.00 61.45 ? 445 VAL A C 1 ATOM 3497 O O . VAL A 1 445 ? -49.523 -25.604 8.076 1.00 61.43 ? 445 VAL A O 1 ATOM 3498 C CB . VAL A 1 445 ? -47.836 -23.238 9.546 1.00 60.69 ? 445 VAL A CB 1 ATOM 3499 C CG1 . VAL A 1 445 ? -48.972 -22.620 8.796 1.00 60.33 ? 445 VAL A CG1 1 ATOM 3500 C CG2 . VAL A 1 445 ? -47.706 -22.584 10.872 1.00 60.98 ? 445 VAL A CG2 1 ATOM 3501 N N . PHE A 1 446 ? -47.310 -25.747 7.643 1.00 62.17 ? 446 PHE A N 1 ATOM 3502 C CA . PHE A 1 446 ? -47.492 -26.385 6.312 1.00 62.60 ? 446 PHE A CA 1 ATOM 3503 C C . PHE A 1 446 ? -47.767 -27.881 6.417 1.00 63.58 ? 446 PHE A C 1 ATOM 3504 O O . PHE A 1 446 ? -47.929 -28.583 5.420 1.00 62.83 ? 446 PHE A O 1 ATOM 3505 C CB . PHE A 1 446 ? -46.307 -26.134 5.415 1.00 61.87 ? 446 PHE A CB 1 ATOM 3506 C CG . PHE A 1 446 ? -46.293 -24.775 4.807 1.00 60.94 ? 446 PHE A CG 1 ATOM 3507 C CD1 . PHE A 1 446 ? -45.808 -23.691 5.514 1.00 60.22 ? 446 PHE A CD1 1 ATOM 3508 C CD2 . PHE A 1 446 ? -46.739 -24.575 3.513 1.00 60.22 ? 446 PHE A CD2 1 ATOM 3509 C CE1 . PHE A 1 446 ? -45.774 -22.423 4.939 1.00 60.69 ? 446 PHE A CE1 1 ATOM 3510 C CE2 . PHE A 1 446 ? -46.707 -23.311 2.935 1.00 60.06 ? 446 PHE A CE2 1 ATOM 3511 C CZ . PHE A 1 446 ? -46.228 -22.230 3.652 1.00 59.83 ? 446 PHE A CZ 1 ATOM 3512 N N . GLY A 1 447 ? -47.810 -28.345 7.661 1.00 65.12 ? 447 GLY A N 1 ATOM 3513 C CA . GLY A 1 447 ? -48.287 -29.675 7.986 1.00 66.96 ? 447 GLY A CA 1 ATOM 3514 C C . GLY A 1 447 ? -47.266 -30.762 7.765 1.00 68.25 ? 447 GLY A C 1 ATOM 3515 O O . GLY A 1 447 ? -47.616 -31.924 7.603 1.00 68.50 ? 447 GLY A O 1 ATOM 3516 N N . LEU A 1 448 ? -45.991 -30.404 7.766 1.00 69.54 ? 448 LEU A N 1 ATOM 3517 C CA . LEU A 1 448 ? -44.970 -31.407 7.484 1.00 70.99 ? 448 LEU A CA 1 ATOM 3518 C C . LEU A 1 448 ? -45.041 -32.639 8.406 1.00 72.34 ? 448 LEU A C 1 ATOM 3519 O O . LEU A 1 448 ? -44.826 -33.762 7.958 1.00 72.64 ? 448 LEU A O 1 ATOM 3520 C CB . LEU A 1 448 ? -43.566 -30.789 7.461 1.00 70.42 ? 448 LEU A CB 1 ATOM 3521 C CG . LEU A 1 448 ? -43.251 -30.261 6.076 1.00 69.36 ? 448 LEU A CG 1 ATOM 3522 C CD1 . LEU A 1 448 ? -44.232 -29.185 5.716 1.00 68.58 ? 448 LEU A CD1 1 ATOM 3523 C CD2 . LEU A 1 448 ? -41.844 -29.770 6.008 1.00 68.47 ? 448 LEU A CD2 1 ATOM 3524 N N . PRO A 1 449 ? -45.335 -32.431 9.695 1.00 73.44 ? 449 PRO A N 1 ATOM 3525 C CA . PRO A 1 449 ? -45.433 -33.564 10.598 1.00 74.45 ? 449 PRO A CA 1 ATOM 3526 C C . PRO A 1 449 ? -46.603 -34.504 10.289 1.00 75.75 ? 449 PRO A C 1 ATOM 3527 O O . PRO A 1 449 ? -46.799 -35.492 10.994 1.00 75.72 ? 449 PRO A O 1 ATOM 3528 C CB . PRO A 1 449 ? -45.644 -32.900 11.964 1.00 74.33 ? 449 PRO A CB 1 ATOM 3529 C CG . PRO A 1 449 ? -45.097 -31.545 11.816 1.00 73.70 ? 449 PRO A CG 1 ATOM 3530 C CD . PRO A 1 449 ? -45.380 -31.148 10.412 1.00 73.43 ? 449 PRO A CD 1 ATOM 3531 N N . LEU A 1 450 ? -47.384 -34.200 9.258 1.00 77.47 ? 450 LEU A N 1 ATOM 3532 C CA . LEU A 1 450 ? -48.538 -35.035 8.924 1.00 79.49 ? 450 LEU A CA 1 ATOM 3533 C C . LEU A 1 450 ? -48.083 -36.244 8.118 1.00 81.69 ? 450 LEU A C 1 ATOM 3534 O O . LEU A 1 450 ? -48.769 -37.253 8.021 1.00 81.83 ? 450 LEU A O 1 ATOM 3535 C CB . LEU A 1 450 ? -49.576 -34.227 8.151 1.00 78.88 ? 450 LEU A CB 1 ATOM 3536 C CG . LEU A 1 450 ? -50.290 -33.143 8.961 1.00 77.48 ? 450 LEU A CG 1 ATOM 3537 C CD1 . LEU A 1 450 ? -51.218 -32.344 8.078 1.00 75.90 ? 450 LEU A CD1 1 ATOM 3538 C CD2 . LEU A 1 450 ? -51.057 -33.748 10.133 1.00 76.67 ? 450 LEU A CD2 1 ATOM 3539 N N . GLU A 1 451 ? -46.899 -36.104 7.543 1.00 84.61 ? 451 GLU A N 1 ATOM 3540 C CA . GLU A 1 451 ? -46.222 -37.142 6.811 1.00 87.49 ? 451 GLU A CA 1 ATOM 3541 C C . GLU A 1 451 ? -45.709 -38.230 7.744 1.00 89.08 ? 451 GLU A C 1 ATOM 3542 O O . GLU A 1 451 ? -44.769 -38.017 8.507 1.00 88.79 ? 451 GLU A O 1 ATOM 3543 C CB . GLU A 1 451 ? -45.043 -36.500 6.114 1.00 87.77 ? 451 GLU A CB 1 ATOM 3544 C CG . GLU A 1 451 ? -44.268 -37.422 5.275 1.00 90.90 ? 451 GLU A CG 1 ATOM 3545 C CD . GLU A 1 451 ? -44.872 -37.513 3.915 1.00 95.57 ? 451 GLU A CD 1 ATOM 3546 O OE1 . GLU A 1 451 ? -44.437 -36.727 3.029 1.00 96.93 ? 451 GLU A OE1 1 ATOM 3547 O OE2 . GLU A 1 451 ? -45.812 -38.339 3.759 1.00 97.38 ? 451 GLU A OE2 1 ATOM 3548 N N . ARG A 1 452 ? -46.332 -39.401 7.670 1.00 91.68 ? 452 ARG A N 1 ATOM 3549 C CA . ARG A 1 452 ? -46.085 -40.490 8.631 1.00 94.07 ? 452 ARG A CA 1 ATOM 3550 C C . ARG A 1 452 ? -44.615 -40.933 8.687 1.00 94.80 ? 452 ARG A C 1 ATOM 3551 O O . ARG A 1 452 ? -43.940 -40.771 9.708 1.00 95.10 ? 452 ARG A O 1 ATOM 3552 C CB . ARG A 1 452 ? -47.024 -41.691 8.355 1.00 94.65 ? 452 ARG A CB 1 ATOM 3553 C CG . ARG A 1 452 ? -48.519 -41.439 8.669 1.00 97.26 ? 452 ARG A CG 1 ATOM 3554 C CD . ARG A 1 452 ? -48.763 -41.254 10.186 1.00 102.03 ? 452 ARG A CD 1 ATOM 3555 N NE . ARG A 1 452 ? -47.790 -40.334 10.798 1.00 105.67 ? 452 ARG A NE 1 ATOM 3556 C CZ . ARG A 1 452 ? -47.749 -39.998 12.091 1.00 107.41 ? 452 ARG A CZ 1 ATOM 3557 N NH1 . ARG A 1 452 ? -48.643 -40.486 12.957 1.00 108.48 ? 452 ARG A NH1 1 ATOM 3558 N NH2 . ARG A 1 452 ? -46.814 -39.154 12.521 1.00 107.87 ? 452 ARG A NH2 1 ATOM 3559 N N . ARG A 1 453 ? -44.133 -41.491 7.581 1.00 95.78 ? 453 ARG A N 1 ATOM 3560 C CA . ARG A 1 453 ? -42.723 -41.819 7.428 1.00 96.54 ? 453 ARG A CA 1 ATOM 3561 C C . ARG A 1 453 ? -41.905 -40.530 7.444 1.00 96.02 ? 453 ARG A C 1 ATOM 3562 O O . ARG A 1 453 ? -41.388 -40.120 6.401 1.00 95.96 ? 453 ARG A O 1 ATOM 3563 C CB . ARG A 1 453 ? -42.501 -42.528 6.086 1.00 97.30 ? 453 ARG A CB 1 ATOM 3564 C CG . ARG A 1 453 ? -43.407 -43.748 5.822 1.00 99.74 ? 453 ARG A CG 1 ATOM 3565 C CD . ARG A 1 453 ? -42.721 -45.061 6.227 1.00 103.53 ? 453 ARG A CD 1 ATOM 3566 N NE . ARG A 1 453 ? -43.536 -46.234 5.898 1.00 105.48 ? 453 ARG A NE 1 ATOM 3567 C CZ . ARG A 1 453 ? -43.301 -47.465 6.344 1.00 106.21 ? 453 ARG A CZ 1 ATOM 3568 N NH1 . ARG A 1 453 ? -42.274 -47.685 7.159 1.00 106.14 ? 453 ARG A NH1 1 ATOM 3569 N NH2 . ARG A 1 453 ? -44.098 -48.468 5.984 1.00 106.22 ? 453 ARG A NH2 1 ATOM 3570 N N . ASP A 1 454 ? -41.799 -39.882 8.606 1.00 95.37 ? 454 ASP A N 1 ATOM 3571 C CA . ASP A 1 454 ? -41.084 -38.603 8.690 1.00 94.59 ? 454 ASP A CA 1 ATOM 3572 C C . ASP A 1 454 ? -40.503 -38.370 10.068 1.00 93.67 ? 454 ASP A C 1 ATOM 3573 O O . ASP A 1 454 ? -39.634 -37.515 10.258 1.00 93.30 ? 454 ASP A O 1 ATOM 3574 C CB . ASP A 1 454 ? -41.995 -37.437 8.311 1.00 94.87 ? 454 ASP A CB 1 ATOM 3575 C CG . ASP A 1 454 ? -41.246 -36.313 7.593 1.00 95.63 ? 454 ASP A CG 1 ATOM 3576 O OD1 . ASP A 1 454 ? -39.993 -36.291 7.649 1.00 96.04 ? 454 ASP A OD1 1 ATOM 3577 O OD2 . ASP A 1 454 ? -41.912 -35.451 6.964 1.00 96.80 ? 454 ASP A OD2 1 ATOM 3578 N N . ASN A 1 455 ? -40.992 -39.127 11.034 1.00 92.54 ? 455 ASN A N 1 ATOM 3579 C CA . ASN A 1 455 ? -40.311 -39.170 12.307 1.00 91.84 ? 455 ASN A CA 1 ATOM 3580 C C . ASN A 1 455 ? -40.538 -37.968 13.209 1.00 90.62 ? 455 ASN A C 1 ATOM 3581 O O . ASN A 1 455 ? -39.735 -37.705 14.104 1.00 90.60 ? 455 ASN A O 1 ATOM 3582 C CB . ASN A 1 455 ? -38.806 -39.349 12.089 1.00 92.31 ? 455 ASN A CB 1 ATOM 3583 C CG . ASN A 1 455 ? -38.451 -40.733 11.570 1.00 93.82 ? 455 ASN A CG 1 ATOM 3584 O OD1 . ASN A 1 455 ? -39.297 -41.434 10.998 1.00 95.60 ? 455 ASN A OD1 1 ATOM 3585 N ND2 . ASN A 1 455 ? -37.197 -41.134 11.763 1.00 94.60 ? 455 ASN A ND2 1 ATOM 3586 N N . TYR A 1 456 ? -41.606 -37.217 12.984 1.00 88.93 ? 456 TYR A N 1 ATOM 3587 C CA . TYR A 1 456 ? -42.034 -36.313 14.029 1.00 87.06 ? 456 TYR A CA 1 ATOM 3588 C C . TYR A 1 456 ? -42.827 -37.208 14.956 1.00 86.07 ? 456 TYR A C 1 ATOM 3589 O O . TYR A 1 456 ? -43.208 -38.290 14.567 1.00 85.97 ? 456 TYR A O 1 ATOM 3590 C CB . TYR A 1 456 ? -42.921 -35.207 13.488 1.00 86.95 ? 456 TYR A CB 1 ATOM 3591 C CG . TYR A 1 456 ? -42.251 -34.207 12.568 1.00 85.60 ? 456 TYR A CG 1 ATOM 3592 C CD1 . TYR A 1 456 ? -42.181 -34.431 11.200 1.00 84.20 ? 456 TYR A CD1 1 ATOM 3593 C CD2 . TYR A 1 456 ? -41.739 -33.016 13.061 1.00 84.07 ? 456 TYR A CD2 1 ATOM 3594 C CE1 . TYR A 1 456 ? -41.608 -33.515 10.360 1.00 83.84 ? 456 TYR A CE1 1 ATOM 3595 C CE2 . TYR A 1 456 ? -41.158 -32.091 12.221 1.00 83.28 ? 456 TYR A CE2 1 ATOM 3596 C CZ . TYR A 1 456 ? -41.100 -32.349 10.872 1.00 83.51 ? 456 TYR A CZ 1 ATOM 3597 O OH . TYR A 1 456 ? -40.523 -31.447 10.015 1.00 83.59 ? 456 TYR A OH 1 ATOM 3598 N N . THR A 1 457 ? -43.091 -36.767 16.171 1.00 84.87 ? 457 THR A N 1 ATOM 3599 C CA . THR A 1 457 ? -43.766 -37.616 17.124 1.00 83.77 ? 457 THR A CA 1 ATOM 3600 C C . THR A 1 457 ? -45.255 -37.621 16.907 1.00 83.30 ? 457 THR A C 1 ATOM 3601 O O . THR A 1 457 ? -45.763 -36.903 16.070 1.00 83.31 ? 457 THR A O 1 ATOM 3602 C CB . THR A 1 457 ? -43.491 -37.141 18.512 1.00 83.67 ? 457 THR A CB 1 ATOM 3603 O OG1 . THR A 1 457 ? -44.144 -35.889 18.719 1.00 83.67 ? 457 THR A OG1 1 ATOM 3604 C CG2 . THR A 1 457 ? -42.025 -36.927 18.650 1.00 83.98 ? 457 THR A CG2 1 ATOM 3605 N N . LYS A 1 458 ? -45.964 -38.442 17.662 1.00 82.91 ? 458 LYS A N 1 ATOM 3606 C CA . LYS A 1 458 ? -47.411 -38.487 17.553 1.00 82.51 ? 458 LYS A CA 1 ATOM 3607 C C . LYS A 1 458 ? -47.962 -37.185 18.097 1.00 81.75 ? 458 LYS A C 1 ATOM 3608 O O . LYS A 1 458 ? -48.833 -36.549 17.504 1.00 81.54 ? 458 LYS A O 1 ATOM 3609 C CB . LYS A 1 458 ? -47.966 -39.653 18.364 1.00 82.91 ? 458 LYS A CB 1 ATOM 3610 C CG . LYS A 1 458 ? -49.275 -40.187 17.817 1.00 84.32 ? 458 LYS A CG 1 ATOM 3611 C CD . LYS A 1 458 ? -49.141 -40.487 16.317 1.00 87.05 ? 458 LYS A CD 1 ATOM 3612 C CE . LYS A 1 458 ? -50.452 -40.979 15.734 1.00 87.87 ? 458 LYS A CE 1 ATOM 3613 N NZ . LYS A 1 458 ? -51.407 -39.849 15.608 1.00 88.29 ? 458 LYS A NZ 1 ATOM 3614 N N . ALA A 1 459 ? -47.432 -36.801 19.246 1.00 80.82 ? 459 ALA A N 1 ATOM 3615 C CA . ALA A 1 459 ? -47.732 -35.520 19.811 1.00 80.05 ? 459 ALA A CA 1 ATOM 3616 C C . ALA A 1 459 ? -47.675 -34.520 18.672 1.00 79.62 ? 459 ALA A C 1 ATOM 3617 O O . ALA A 1 459 ? -48.601 -33.743 18.466 1.00 79.91 ? 459 ALA A O 1 ATOM 3618 C CB . ALA A 1 459 ? -46.715 -35.179 20.896 1.00 79.83 ? 459 ALA A CB 1 ATOM 3619 N N . GLU A 1 460 ? -46.597 -34.564 17.905 1.00 78.93 ? 460 GLU A N 1 ATOM 3620 C CA . GLU A 1 460 ? -46.355 -33.532 16.926 1.00 78.24 ? 460 GLU A CA 1 ATOM 3621 C C . GLU A 1 460 ? -47.309 -33.599 15.747 1.00 77.97 ? 460 GLU A C 1 ATOM 3622 O O . GLU A 1 460 ? -47.716 -32.568 15.217 1.00 78.02 ? 460 GLU A O 1 ATOM 3623 C CB . GLU A 1 460 ? -44.905 -33.558 16.471 1.00 78.25 ? 460 GLU A CB 1 ATOM 3624 C CG . GLU A 1 460 ? -43.941 -33.103 17.534 1.00 78.03 ? 460 GLU A CG 1 ATOM 3625 C CD . GLU A 1 460 ? -42.525 -33.073 17.025 1.00 79.10 ? 460 GLU A CD 1 ATOM 3626 O OE1 . GLU A 1 460 ? -42.217 -33.862 16.113 1.00 79.38 ? 460 GLU A OE1 1 ATOM 3627 O OE2 . GLU A 1 460 ? -41.715 -32.262 17.520 1.00 79.86 ? 460 GLU A OE2 1 ATOM 3628 N N . GLU A 1 461 ? -47.682 -34.805 15.338 1.00 77.68 ? 461 GLU A N 1 ATOM 3629 C CA . GLU A 1 461 ? -48.623 -34.939 14.236 1.00 77.37 ? 461 GLU A CA 1 ATOM 3630 C C . GLU A 1 461 ? -49.950 -34.304 14.621 1.00 76.22 ? 461 GLU A C 1 ATOM 3631 O O . GLU A 1 461 ? -50.553 -33.545 13.856 1.00 75.87 ? 461 GLU A O 1 ATOM 3632 C CB . GLU A 1 461 ? -48.848 -36.401 13.848 1.00 77.97 ? 461 GLU A CB 1 ATOM 3633 C CG . GLU A 1 461 ? -49.697 -36.515 12.554 1.00 81.30 ? 461 GLU A CG 1 ATOM 3634 C CD . GLU A 1 461 ? -50.465 -37.866 12.340 1.00 84.30 ? 461 GLU A CD 1 ATOM 3635 O OE1 . GLU A 1 461 ? -50.838 -38.161 11.160 1.00 84.60 ? 461 GLU A OE1 1 ATOM 3636 O OE2 . GLU A 1 461 ? -50.706 -38.615 13.327 1.00 84.87 ? 461 GLU A OE2 1 ATOM 3637 N N . ILE A 1 462 ? -50.400 -34.615 15.826 1.00 75.04 ? 462 ILE A N 1 ATOM 3638 C CA . ILE A 1 462 ? -51.623 -34.033 16.319 1.00 74.20 ? 462 ILE A CA 1 ATOM 3639 C C . ILE A 1 462 ? -51.526 -32.531 16.213 1.00 73.31 ? 462 ILE A C 1 ATOM 3640 O O . ILE A 1 462 ? -52.254 -31.925 15.437 1.00 73.49 ? 462 ILE A O 1 ATOM 3641 C CB . ILE A 1 462 ? -51.893 -34.439 17.776 1.00 74.71 ? 462 ILE A CB 1 ATOM 3642 C CG1 . ILE A 1 462 ? -52.273 -35.936 17.837 1.00 75.27 ? 462 ILE A CG1 1 ATOM 3643 C CG2 . ILE A 1 462 ? -52.953 -33.510 18.426 1.00 74.07 ? 462 ILE A CG2 1 ATOM 3644 C CD1 . ILE A 1 462 ? -53.295 -36.375 16.734 1.00 75.52 ? 462 ILE A CD1 1 ATOM 3645 N N . LEU A 1 463 ? -50.612 -31.937 16.978 1.00 71.86 ? 463 LEU A N 1 ATOM 3646 C CA . LEU A 1 463 ? -50.388 -30.487 16.951 1.00 70.37 ? 463 LEU A CA 1 ATOM 3647 C C . LEU A 1 463 ? -50.498 -29.868 15.542 1.00 69.36 ? 463 LEU A C 1 ATOM 3648 O O . LEU A 1 463 ? -51.263 -28.935 15.305 1.00 68.90 ? 463 LEU A O 1 ATOM 3649 C CB . LEU A 1 463 ? -49.024 -30.166 17.551 1.00 70.17 ? 463 LEU A CB 1 ATOM 3650 C CG . LEU A 1 463 ? -48.702 -28.686 17.734 1.00 69.57 ? 463 LEU A CG 1 ATOM 3651 C CD1 . LEU A 1 463 ? -49.778 -28.014 18.536 1.00 68.79 ? 463 LEU A CD1 1 ATOM 3652 C CD2 . LEU A 1 463 ? -47.356 -28.509 18.409 1.00 68.97 ? 463 LEU A CD2 1 ATOM 3653 N N . SER A 1 464 ? -49.735 -30.398 14.605 1.00 68.14 ? 464 SER A N 1 ATOM 3654 C CA . SER A 1 464 ? -49.760 -29.847 13.282 1.00 67.20 ? 464 SER A CA 1 ATOM 3655 C C . SER A 1 464 ? -51.160 -29.907 12.718 1.00 66.77 ? 464 SER A C 1 ATOM 3656 O O . SER A 1 464 ? -51.636 -28.963 12.091 1.00 66.51 ? 464 SER A O 1 ATOM 3657 C CB . SER A 1 464 ? -48.796 -30.585 12.375 1.00 66.85 ? 464 SER A CB 1 ATOM 3658 O OG . SER A 1 464 ? -48.684 -29.887 11.153 1.00 66.47 ? 464 SER A OG 1 ATOM 3659 N N . ARG A 1 465 ? -51.818 -31.032 12.947 1.00 66.59 ? 465 ARG A N 1 ATOM 3660 C CA . ARG A 1 465 ? -53.159 -31.255 12.406 1.00 66.40 ? 465 ARG A CA 1 ATOM 3661 C C . ARG A 1 465 ? -54.088 -30.180 12.935 1.00 65.27 ? 465 ARG A C 1 ATOM 3662 O O . ARG A 1 465 ? -54.959 -29.683 12.236 1.00 65.26 ? 465 ARG A O 1 ATOM 3663 C CB . ARG A 1 465 ? -53.675 -32.648 12.791 1.00 66.81 ? 465 ARG A CB 1 ATOM 3664 C CG . ARG A 1 465 ? -55.084 -32.944 12.278 1.00 69.01 ? 465 ARG A CG 1 ATOM 3665 C CD . ARG A 1 465 ? -55.119 -33.033 10.745 1.00 72.18 ? 465 ARG A CD 1 ATOM 3666 N NE . ARG A 1 465 ? -56.447 -32.806 10.159 1.00 73.72 ? 465 ARG A NE 1 ATOM 3667 C CZ . ARG A 1 465 ? -56.867 -31.632 9.683 1.00 75.11 ? 465 ARG A CZ 1 ATOM 3668 N NH1 . ARG A 1 465 ? -56.082 -30.565 9.731 1.00 76.08 ? 465 ARG A NH1 1 ATOM 3669 N NH2 . ARG A 1 465 ? -58.077 -31.516 9.167 1.00 75.99 ? 465 ARG A NH2 1 ATOM 3670 N N . SER A 1 466 ? -53.856 -29.806 14.181 1.00 63.99 ? 466 SER A N 1 ATOM 3671 C CA . SER A 1 466 ? -54.651 -28.811 14.836 1.00 62.53 ? 466 SER A CA 1 ATOM 3672 C C . SER A 1 466 ? -54.396 -27.432 14.263 1.00 61.57 ? 466 SER A C 1 ATOM 3673 O O . SER A 1 466 ? -55.329 -26.723 13.909 1.00 61.50 ? 466 SER A O 1 ATOM 3674 C CB . SER A 1 466 ? -54.333 -28.820 16.316 1.00 62.32 ? 466 SER A CB 1 ATOM 3675 O OG . SER A 1 466 ? -55.379 -28.185 17.003 1.00 63.09 ? 466 SER A OG 1 ATOM 3676 N N . ILE A 1 467 ? -53.126 -27.056 14.178 1.00 60.51 ? 467 ILE A N 1 ATOM 3677 C CA . ILE A 1 467 ? -52.747 -25.764 13.645 1.00 59.33 ? 467 ILE A CA 1 ATOM 3678 C C . ILE A 1 467 ? -53.252 -25.648 12.231 1.00 59.11 ? 467 ILE A C 1 ATOM 3679 O O . ILE A 1 467 ? -53.906 -24.671 11.872 1.00 59.27 ? 467 ILE A O 1 ATOM 3680 C CB . ILE A 1 467 ? -51.227 -25.576 13.673 1.00 59.06 ? 467 ILE A CB 1 ATOM 3681 C CG1 . ILE A 1 467 ? -50.762 -25.432 15.126 1.00 58.19 ? 467 ILE A CG1 1 ATOM 3682 C CG2 . ILE A 1 467 ? -50.819 -24.366 12.848 1.00 58.29 ? 467 ILE A CG2 1 ATOM 3683 C CD1 . ILE A 1 467 ? -49.271 -25.462 15.320 1.00 56.63 ? 467 ILE A CD1 1 ATOM 3684 N N . VAL A 1 468 ? -52.974 -26.667 11.432 1.00 58.58 ? 468 VAL A N 1 ATOM 3685 C CA . VAL A 1 468 ? -53.405 -26.660 10.046 1.00 58.09 ? 468 VAL A CA 1 ATOM 3686 C C . VAL A 1 468 ? -54.877 -26.302 9.963 1.00 57.74 ? 468 VAL A C 1 ATOM 3687 O O . VAL A 1 468 ? -55.279 -25.432 9.195 1.00 57.85 ? 468 VAL A O 1 ATOM 3688 C CB . VAL A 1 468 ? -53.133 -28.005 9.341 1.00 58.08 ? 468 VAL A CB 1 ATOM 3689 C CG1 . VAL A 1 468 ? -53.897 -28.066 8.024 1.00 57.59 ? 468 VAL A CG1 1 ATOM 3690 C CG2 . VAL A 1 468 ? -51.624 -28.191 9.107 1.00 57.47 ? 468 VAL A CG2 1 ATOM 3691 N N . LYS A 1 469 ? -55.674 -26.969 10.775 1.00 57.29 ? 469 LYS A N 1 ATOM 3692 C CA . LYS A 1 469 ? -57.096 -26.705 10.822 1.00 57.09 ? 469 LYS A CA 1 ATOM 3693 C C . LYS A 1 469 ? -57.411 -25.275 11.247 1.00 56.76 ? 469 LYS A C 1 ATOM 3694 O O . LYS A 1 469 ? -58.217 -24.607 10.620 1.00 56.72 ? 469 LYS A O 1 ATOM 3695 C CB . LYS A 1 469 ? -57.762 -27.676 11.789 1.00 57.35 ? 469 LYS A CB 1 ATOM 3696 C CG . LYS A 1 469 ? -59.195 -27.332 12.101 1.00 57.80 ? 469 LYS A CG 1 ATOM 3697 C CD . LYS A 1 469 ? -60.038 -27.341 10.835 1.00 57.06 ? 469 LYS A CD 1 ATOM 3698 C CE . LYS A 1 469 ? -59.827 -28.617 10.079 1.00 56.45 ? 469 LYS A CE 1 ATOM 3699 N NZ . LYS A 1 469 ? -60.945 -28.806 9.168 1.00 56.74 ? 469 LYS A NZ 1 ATOM 3700 N N . ARG A 1 470 ? -56.787 -24.812 12.322 1.00 56.17 ? 470 ARG A N 1 ATOM 3701 C CA . ARG A 1 470 ? -57.073 -23.490 12.833 1.00 55.65 ? 470 ARG A CA 1 ATOM 3702 C C . ARG A 1 470 ? -56.799 -22.453 11.761 1.00 55.56 ? 470 ARG A C 1 ATOM 3703 O O . ARG A 1 470 ? -57.630 -21.597 11.467 1.00 55.38 ? 470 ARG A O 1 ATOM 3704 C CB . ARG A 1 470 ? -56.238 -23.213 14.081 1.00 55.57 ? 470 ARG A CB 1 ATOM 3705 C CG . ARG A 1 470 ? -56.623 -24.047 15.292 1.00 54.38 ? 470 ARG A CG 1 ATOM 3706 C CD . ARG A 1 470 ? -56.007 -23.466 16.520 1.00 52.45 ? 470 ARG A CD 1 ATOM 3707 N NE . ARG A 1 470 ? -56.405 -24.128 17.749 1.00 50.86 ? 470 ARG A NE 1 ATOM 3708 C CZ . ARG A 1 470 ? -57.468 -23.783 18.469 1.00 51.09 ? 470 ARG A CZ 1 ATOM 3709 N NH1 . ARG A 1 470 ? -57.747 -24.425 19.605 1.00 51.58 ? 470 ARG A NH1 1 ATOM 3710 N NH2 . ARG A 1 470 ? -58.262 -22.800 18.052 1.00 50.31 ? 470 ARG A NH2 1 ATOM 3711 N N . TRP A 1 471 ? -55.618 -22.543 11.172 1.00 55.62 ? 471 TRP A N 1 ATOM 3712 C CA . TRP A 1 471 ? -55.242 -21.673 10.078 1.00 55.99 ? 471 TRP A CA 1 ATOM 3713 C C . TRP A 1 471 ? -56.283 -21.790 8.984 1.00 56.33 ? 471 TRP A C 1 ATOM 3714 O O . TRP A 1 471 ? -56.912 -20.814 8.606 1.00 56.63 ? 471 TRP A O 1 ATOM 3715 C CB . TRP A 1 471 ? -53.878 -22.083 9.532 1.00 55.88 ? 471 TRP A CB 1 ATOM 3716 C CG . TRP A 1 471 ? -52.725 -21.318 10.083 1.00 56.03 ? 471 TRP A CG 1 ATOM 3717 C CD1 . TRP A 1 471 ? -51.760 -20.656 9.365 1.00 56.63 ? 471 TRP A CD1 1 ATOM 3718 C CD2 . TRP A 1 471 ? -52.394 -21.131 11.463 1.00 55.42 ? 471 TRP A CD2 1 ATOM 3719 N NE1 . TRP A 1 471 ? -50.855 -20.067 10.219 1.00 56.65 ? 471 TRP A NE1 1 ATOM 3720 C CE2 . TRP A 1 471 ? -51.225 -20.344 11.511 1.00 55.93 ? 471 TRP A CE2 1 ATOM 3721 C CE3 . TRP A 1 471 ? -52.967 -21.550 12.655 1.00 54.09 ? 471 TRP A CE3 1 ATOM 3722 C CZ2 . TRP A 1 471 ? -50.636 -19.972 12.706 1.00 55.14 ? 471 TRP A CZ2 1 ATOM 3723 C CZ3 . TRP A 1 471 ? -52.386 -21.173 13.824 1.00 53.70 ? 471 TRP A CZ3 1 ATOM 3724 C CH2 . TRP A 1 471 ? -51.237 -20.397 13.850 1.00 53.96 ? 471 TRP A CH2 1 ATOM 3725 N N . ALA A 1 472 ? -56.474 -22.998 8.483 1.00 56.62 ? 472 ALA A N 1 ATOM 3726 C CA . ALA A 1 472 ? -57.430 -23.234 7.411 1.00 56.93 ? 472 ALA A CA 1 ATOM 3727 C C . ALA A 1 472 ? -58.748 -22.545 7.704 1.00 57.30 ? 472 ALA A C 1 ATOM 3728 O O . ALA A 1 472 ? -59.236 -21.751 6.907 1.00 57.46 ? 472 ALA A O 1 ATOM 3729 C CB . ALA A 1 472 ? -57.639 -24.705 7.240 1.00 56.94 ? 472 ALA A CB 1 ATOM 3730 N N . ASN A 1 473 ? -59.311 -22.854 8.863 1.00 57.73 ? 473 ASN A N 1 ATOM 3731 C CA . ASN A 1 473 ? -60.516 -22.218 9.331 1.00 58.18 ? 473 ASN A CA 1 ATOM 3732 C C . ASN A 1 473 ? -60.383 -20.722 9.324 1.00 58.13 ? 473 ASN A C 1 ATOM 3733 O O . ASN A 1 473 ? -61.239 -20.049 8.766 1.00 58.58 ? 473 ASN A O 1 ATOM 3734 C CB . ASN A 1 473 ? -60.882 -22.695 10.737 1.00 58.66 ? 473 ASN A CB 1 ATOM 3735 C CG . ASN A 1 473 ? -61.801 -23.904 10.721 1.00 60.56 ? 473 ASN A CG 1 ATOM 3736 O OD1 . ASN A 1 473 ? -62.541 -24.103 9.765 1.00 63.77 ? 473 ASN A OD1 1 ATOM 3737 N ND2 . ASN A 1 473 ? -61.760 -24.714 11.778 1.00 61.31 ? 473 ASN A ND2 1 ATOM 3738 N N . PHE A 1 474 ? -59.326 -20.186 9.931 1.00 57.80 ? 474 PHE A N 1 ATOM 3739 C CA . PHE A 1 474 ? -59.171 -18.737 9.940 1.00 57.62 ? 474 PHE A CA 1 ATOM 3740 C C . PHE A 1 474 ? -59.238 -18.149 8.517 1.00 58.00 ? 474 PHE A C 1 ATOM 3741 O O . PHE A 1 474 ? -59.906 -17.136 8.267 1.00 57.86 ? 474 PHE A O 1 ATOM 3742 C CB . PHE A 1 474 ? -57.878 -18.287 10.613 1.00 57.26 ? 474 PHE A CB 1 ATOM 3743 C CG . PHE A 1 474 ? -57.626 -16.804 10.462 1.00 56.71 ? 474 PHE A CG 1 ATOM 3744 C CD1 . PHE A 1 474 ? -58.184 -15.901 11.352 1.00 54.56 ? 474 PHE A CD1 1 ATOM 3745 C CD2 . PHE A 1 474 ? -56.876 -16.304 9.394 1.00 55.46 ? 474 PHE A CD2 1 ATOM 3746 C CE1 . PHE A 1 474 ? -57.972 -14.545 11.184 1.00 54.10 ? 474 PHE A CE1 1 ATOM 3747 C CE2 . PHE A 1 474 ? -56.672 -14.933 9.233 1.00 53.95 ? 474 PHE A CE2 1 ATOM 3748 C CZ . PHE A 1 474 ? -57.215 -14.062 10.123 1.00 52.72 ? 474 PHE A CZ 1 ATOM 3749 N N . ALA A 1 475 ? -58.532 -18.788 7.589 1.00 58.26 ? 475 ALA A N 1 ATOM 3750 C CA . ALA A 1 475 ? -58.587 -18.394 6.195 1.00 58.28 ? 475 ALA A CA 1 ATOM 3751 C C . ALA A 1 475 ? -60.024 -18.391 5.704 1.00 58.43 ? 475 ALA A C 1 ATOM 3752 O O . ALA A 1 475 ? -60.478 -17.406 5.135 1.00 58.49 ? 475 ALA A O 1 ATOM 3753 C CB . ALA A 1 475 ? -57.753 -19.332 5.353 1.00 58.11 ? 475 ALA A CB 1 ATOM 3754 N N . LYS A 1 476 ? -60.731 -19.495 5.925 1.00 58.46 ? 476 LYS A N 1 ATOM 3755 C CA . LYS A 1 476 ? -62.053 -19.674 5.354 1.00 58.85 ? 476 LYS A CA 1 ATOM 3756 C C . LYS A 1 476 ? -63.116 -18.849 6.041 1.00 59.18 ? 476 LYS A C 1 ATOM 3757 O O . LYS A 1 476 ? -63.947 -18.251 5.386 1.00 59.38 ? 476 LYS A O 1 ATOM 3758 C CB . LYS A 1 476 ? -62.476 -21.133 5.413 1.00 59.02 ? 476 LYS A CB 1 ATOM 3759 C CG . LYS A 1 476 ? -61.730 -22.069 4.505 1.00 58.68 ? 476 LYS A CG 1 ATOM 3760 C CD . LYS A 1 476 ? -62.043 -23.502 4.901 1.00 58.56 ? 476 LYS A CD 1 ATOM 3761 C CE . LYS A 1 476 ? -61.415 -24.468 3.938 1.00 59.11 ? 476 LYS A CE 1 ATOM 3762 N NZ . LYS A 1 476 ? -61.319 -25.839 4.453 1.00 58.52 ? 476 LYS A NZ 1 ATOM 3763 N N . TYR A 1 477 ? -63.110 -18.822 7.365 1.00 59.62 ? 477 TYR A N 1 ATOM 3764 C CA . TYR A 1 477 ? -64.193 -18.165 8.065 1.00 59.91 ? 477 TYR A CA 1 ATOM 3765 C C . TYR A 1 477 ? -63.744 -17.051 8.991 1.00 59.74 ? 477 TYR A C 1 ATOM 3766 O O . TYR A 1 477 ? -64.540 -16.478 9.706 1.00 59.56 ? 477 TYR A O 1 ATOM 3767 C CB . TYR A 1 477 ? -65.002 -19.190 8.831 1.00 60.15 ? 477 TYR A CB 1 ATOM 3768 C CG . TYR A 1 477 ? -65.178 -20.469 8.070 1.00 61.89 ? 477 TYR A CG 1 ATOM 3769 C CD1 . TYR A 1 477 ? -64.654 -21.661 8.547 1.00 63.59 ? 477 TYR A CD1 1 ATOM 3770 C CD2 . TYR A 1 477 ? -65.836 -20.488 6.855 1.00 62.75 ? 477 TYR A CD2 1 ATOM 3771 C CE1 . TYR A 1 477 ? -64.809 -22.845 7.850 1.00 64.40 ? 477 TYR A CE1 1 ATOM 3772 C CE2 . TYR A 1 477 ? -66.001 -21.671 6.154 1.00 63.64 ? 477 TYR A CE2 1 ATOM 3773 C CZ . TYR A 1 477 ? -65.477 -22.841 6.657 1.00 64.50 ? 477 TYR A CZ 1 ATOM 3774 O OH . TYR A 1 477 ? -65.618 -24.013 5.961 1.00 65.62 ? 477 TYR A OH 1 ATOM 3775 N N . GLY A 1 478 ? -62.470 -16.723 8.981 1.00 59.97 ? 478 GLY A N 1 ATOM 3776 C CA . GLY A 1 478 ? -62.014 -15.639 9.824 1.00 60.50 ? 478 GLY A CA 1 ATOM 3777 C C . GLY A 1 478 ? -62.176 -15.983 11.289 1.00 60.91 ? 478 GLY A C 1 ATOM 3778 O O . GLY A 1 478 ? -62.500 -15.122 12.113 1.00 61.23 ? 478 GLY A O 1 ATOM 3779 N N . ASN A 1 479 ? -61.944 -17.248 11.619 1.00 60.83 ? 479 ASN A N 1 ATOM 3780 C CA . ASN A 1 479 ? -62.039 -17.692 12.987 1.00 60.82 ? 479 ASN A CA 1 ATOM 3781 C C . ASN A 1 479 ? -61.187 -18.933 13.185 1.00 61.35 ? 479 ASN A C 1 ATOM 3782 O O . ASN A 1 479 ? -61.453 -19.959 12.575 1.00 61.09 ? 479 ASN A O 1 ATOM 3783 C CB . ASN A 1 479 ? -63.491 -17.971 13.328 1.00 60.76 ? 479 ASN A CB 1 ATOM 3784 C CG . ASN A 1 479 ? -63.799 -17.787 14.803 1.00 60.21 ? 479 ASN A CG 1 ATOM 3785 O OD1 . ASN A 1 479 ? -62.963 -18.039 15.652 1.00 60.03 ? 479 ASN A OD1 1 ATOM 3786 N ND2 . ASN A 1 479 ? -65.013 -17.361 15.107 1.00 59.79 ? 479 ASN A ND2 1 ATOM 3787 N N . PRO A 1 480 ? -60.139 -18.828 14.022 1.00 61.88 ? 480 PRO A N 1 ATOM 3788 C CA . PRO A 1 480 ? -59.134 -19.859 14.078 1.00 62.65 ? 480 PRO A CA 1 ATOM 3789 C C . PRO A 1 480 ? -59.464 -20.925 15.073 1.00 63.49 ? 480 PRO A C 1 ATOM 3790 O O . PRO A 1 480 ? -58.584 -21.355 15.812 1.00 63.85 ? 480 PRO A O 1 ATOM 3791 C CB . PRO A 1 480 ? -57.883 -19.103 14.536 1.00 62.45 ? 480 PRO A CB 1 ATOM 3792 C CG . PRO A 1 480 ? -58.388 -17.997 15.300 1.00 61.82 ? 480 PRO A CG 1 ATOM 3793 C CD . PRO A 1 480 ? -59.689 -17.603 14.702 1.00 61.90 ? 480 PRO A CD 1 ATOM 3794 N N . GLN A 1 481 ? -60.713 -21.361 15.087 1.00 64.55 ? 481 GLN A N 1 ATOM 3795 C CA . GLN A 1 481 ? -61.133 -22.396 16.025 1.00 65.65 ? 481 GLN A CA 1 ATOM 3796 C C . GLN A 1 481 ? -60.897 -23.789 15.478 1.00 66.61 ? 481 GLN A C 1 ATOM 3797 O O . GLN A 1 481 ? -60.882 -24.001 14.274 1.00 66.70 ? 481 GLN A O 1 ATOM 3798 C CB . GLN A 1 481 ? -62.611 -22.220 16.361 1.00 65.45 ? 481 GLN A CB 1 ATOM 3799 C CG . GLN A 1 481 ? -62.949 -20.822 16.850 1.00 65.08 ? 481 GLN A CG 1 ATOM 3800 C CD . GLN A 1 481 ? -62.133 -20.425 18.065 1.00 64.78 ? 481 GLN A CD 1 ATOM 3801 O OE1 . GLN A 1 481 ? -61.688 -21.279 18.818 1.00 65.40 ? 481 GLN A OE1 1 ATOM 3802 N NE2 . GLN A 1 481 ? -61.925 -19.133 18.254 1.00 63.42 ? 481 GLN A NE2 1 ATOM 3803 N N . GLU A 1 482 ? -60.700 -24.744 16.371 1.00 68.00 ? 482 GLU A N 1 ATOM 3804 C CA . GLU A 1 482 ? -60.760 -26.148 15.999 1.00 69.41 ? 482 GLU A CA 1 ATOM 3805 C C . GLU A 1 482 ? -61.999 -26.664 16.704 1.00 70.48 ? 482 GLU A C 1 ATOM 3806 O O . GLU A 1 482 ? -61.987 -26.880 17.902 1.00 70.79 ? 482 GLU A O 1 ATOM 3807 C CB . GLU A 1 482 ? -59.523 -26.879 16.493 1.00 69.36 ? 482 GLU A CB 1 ATOM 3808 C CG . GLU A 1 482 ? -59.332 -28.257 15.919 1.00 70.33 ? 482 GLU A CG 1 ATOM 3809 C CD . GLU A 1 482 ? -60.527 -29.140 16.156 1.00 71.97 ? 482 GLU A CD 1 ATOM 3810 O OE1 . GLU A 1 482 ? -61.294 -29.384 15.182 1.00 73.69 ? 482 GLU A OE1 1 ATOM 3811 O OE2 . GLU A 1 482 ? -60.703 -29.572 17.317 1.00 71.52 ? 482 GLU A OE2 1 ATOM 3812 N N . THR A 1 483 ? -63.086 -26.831 15.968 1.00 71.97 ? 483 THR A N 1 ATOM 3813 C CA . THR A 1 483 ? -64.388 -26.980 16.595 1.00 73.17 ? 483 THR A CA 1 ATOM 3814 C C . THR A 1 483 ? -64.753 -28.411 16.945 1.00 74.28 ? 483 THR A C 1 ATOM 3815 O O . THR A 1 483 ? -65.722 -28.636 17.639 1.00 74.74 ? 483 THR A O 1 ATOM 3816 C CB . THR A 1 483 ? -65.511 -26.425 15.695 1.00 73.03 ? 483 THR A CB 1 ATOM 3817 O OG1 . THR A 1 483 ? -65.851 -27.399 14.706 1.00 73.43 ? 483 THR A OG1 1 ATOM 3818 C CG2 . THR A 1 483 ? -65.077 -25.144 15.002 1.00 72.82 ? 483 THR A CG2 1 ATOM 3819 N N . GLN A 1 484 ? -64.000 -29.387 16.471 1.00 75.65 ? 484 GLN A N 1 ATOM 3820 C CA . GLN A 1 484 ? -64.481 -30.753 16.570 1.00 76.95 ? 484 GLN A CA 1 ATOM 3821 C C . GLN A 1 484 ? -63.849 -31.625 17.631 1.00 77.60 ? 484 GLN A C 1 ATOM 3822 O O . GLN A 1 484 ? -64.518 -32.468 18.197 1.00 77.63 ? 484 GLN A O 1 ATOM 3823 C CB . GLN A 1 484 ? -64.378 -31.443 15.225 1.00 77.25 ? 484 GLN A CB 1 ATOM 3824 C CG . GLN A 1 484 ? -65.506 -31.101 14.300 1.00 79.18 ? 484 GLN A CG 1 ATOM 3825 C CD . GLN A 1 484 ? -65.161 -31.409 12.866 1.00 81.51 ? 484 GLN A CD 1 ATOM 3826 O OE1 . GLN A 1 484 ? -66.043 -31.548 12.020 1.00 83.01 ? 484 GLN A OE1 1 ATOM 3827 N NE2 . GLN A 1 484 ? -63.868 -31.517 12.581 1.00 81.03 ? 484 GLN A NE2 1 ATOM 3828 N N . ASN A 1 485 ? -62.565 -31.456 17.895 1.00 78.58 ? 485 ASN A N 1 ATOM 3829 C CA . ASN A 1 485 ? -61.929 -32.314 18.869 1.00 79.66 ? 485 ASN A CA 1 ATOM 3830 C C . ASN A 1 485 ? -61.831 -31.642 20.225 1.00 79.51 ? 485 ASN A C 1 ATOM 3831 O O . ASN A 1 485 ? -60.769 -31.601 20.832 1.00 79.76 ? 485 ASN A O 1 ATOM 3832 C CB . ASN A 1 485 ? -60.572 -32.798 18.377 1.00 80.29 ? 485 ASN A CB 1 ATOM 3833 C CG . ASN A 1 485 ? -60.687 -33.659 17.140 1.00 83.98 ? 485 ASN A CG 1 ATOM 3834 O OD1 . ASN A 1 485 ? -61.786 -34.049 16.753 1.00 84.31 ? 485 ASN A OD1 1 ATOM 3835 N ND2 . ASN A 1 485 ? -59.553 -33.938 16.496 1.00 90.32 ? 485 ASN A ND2 1 ATOM 3836 N N . ASN A 1 486 ? -62.958 -31.102 20.683 1.00 79.30 ? 486 ASN A N 1 ATOM 3837 C CA . ASN A 1 486 ? -63.114 -30.631 22.060 1.00 78.80 ? 486 ASN A CA 1 ATOM 3838 C C . ASN A 1 486 ? -61.992 -29.665 22.473 1.00 78.34 ? 486 ASN A C 1 ATOM 3839 O O . ASN A 1 486 ? -61.514 -29.686 23.614 1.00 78.46 ? 486 ASN A O 1 ATOM 3840 C CB . ASN A 1 486 ? -63.206 -31.843 23.030 1.00 78.70 ? 486 ASN A CB 1 ATOM 3841 N N . SER A 1 487 ? -61.578 -28.808 21.544 1.00 77.39 ? 487 SER A N 1 ATOM 3842 C CA . SER A 1 487 ? -60.369 -28.007 21.751 1.00 76.43 ? 487 SER A CA 1 ATOM 3843 C C . SER A 1 487 ? -60.572 -26.793 22.651 1.00 75.83 ? 487 SER A C 1 ATOM 3844 O O . SER A 1 487 ? -61.689 -26.512 23.075 1.00 76.19 ? 487 SER A O 1 ATOM 3845 C CB . SER A 1 487 ? -59.812 -27.586 20.408 1.00 76.11 ? 487 SER A CB 1 ATOM 3846 O OG . SER A 1 487 ? -59.613 -28.743 19.633 1.00 75.92 ? 487 SER A OG 1 ATOM 3847 N N . THR A 1 488 ? -59.492 -26.083 22.956 1.00 74.55 ? 488 THR A N 1 ATOM 3848 C CA . THR A 1 488 ? -59.620 -24.803 23.634 1.00 73.11 ? 488 THR A CA 1 ATOM 3849 C C . THR A 1 488 ? -60.131 -23.757 22.666 1.00 72.35 ? 488 THR A C 1 ATOM 3850 O O . THR A 1 488 ? -59.606 -23.623 21.564 1.00 72.41 ? 488 THR A O 1 ATOM 3851 C CB . THR A 1 488 ? -58.275 -24.290 24.135 1.00 73.21 ? 488 THR A CB 1 ATOM 3852 O OG1 . THR A 1 488 ? -57.787 -25.137 25.174 1.00 73.05 ? 488 THR A OG1 1 ATOM 3853 C CG2 . THR A 1 488 ? -58.423 -22.879 24.670 1.00 72.67 ? 488 THR A CG2 1 ATOM 3854 N N . SER A 1 489 ? -61.148 -23.011 23.075 1.00 71.04 ? 489 SER A N 1 ATOM 3855 C CA . SER A 1 489 ? -61.640 -21.893 22.288 1.00 69.71 ? 489 SER A CA 1 ATOM 3856 C C . SER A 1 489 ? -60.552 -20.827 22.222 1.00 68.70 ? 489 SER A C 1 ATOM 3857 O O . SER A 1 489 ? -59.914 -20.545 23.220 1.00 68.76 ? 489 SER A O 1 ATOM 3858 C CB . SER A 1 489 ? -62.867 -21.316 22.970 1.00 69.84 ? 489 SER A CB 1 ATOM 3859 O OG . SER A 1 489 ? -63.832 -20.919 22.030 1.00 70.47 ? 489 SER A OG 1 ATOM 3860 N N . TRP A 1 490 ? -60.321 -20.250 21.050 1.00 67.60 ? 490 TRP A N 1 ATOM 3861 C CA . TRP A 1 490 ? -59.257 -19.259 20.872 1.00 66.26 ? 490 TRP A CA 1 ATOM 3862 C C . TRP A 1 490 ? -59.883 -17.888 20.898 1.00 65.79 ? 490 TRP A C 1 ATOM 3863 O O . TRP A 1 490 ? -60.521 -17.484 19.933 1.00 65.66 ? 490 TRP A O 1 ATOM 3864 C CB . TRP A 1 490 ? -58.535 -19.476 19.536 1.00 65.93 ? 490 TRP A CB 1 ATOM 3865 C CG . TRP A 1 490 ? -57.336 -18.589 19.292 1.00 64.79 ? 490 TRP A CG 1 ATOM 3866 C CD1 . TRP A 1 490 ? -57.022 -17.428 19.932 1.00 64.20 ? 490 TRP A CD1 1 ATOM 3867 C CD2 . TRP A 1 490 ? -56.327 -18.775 18.297 1.00 64.46 ? 490 TRP A CD2 1 ATOM 3868 N NE1 . TRP A 1 490 ? -55.868 -16.895 19.419 1.00 63.59 ? 490 TRP A NE1 1 ATOM 3869 C CE2 . TRP A 1 490 ? -55.427 -17.702 18.406 1.00 63.75 ? 490 TRP A CE2 1 ATOM 3870 C CE3 . TRP A 1 490 ? -56.096 -19.748 17.320 1.00 64.56 ? 490 TRP A CE3 1 ATOM 3871 C CZ2 . TRP A 1 490 ? -54.313 -17.580 17.583 1.00 63.33 ? 490 TRP A CZ2 1 ATOM 3872 C CZ3 . TRP A 1 490 ? -54.985 -19.621 16.509 1.00 63.53 ? 490 TRP A CZ3 1 ATOM 3873 C CH2 . TRP A 1 490 ? -54.108 -18.549 16.647 1.00 62.56 ? 490 TRP A CH2 1 ATOM 3874 N N . PRO A 1 491 ? -59.698 -17.166 22.007 1.00 65.29 ? 491 PRO A N 1 ATOM 3875 C CA . PRO A 1 491 ? -60.346 -15.901 22.299 1.00 65.50 ? 491 PRO A CA 1 ATOM 3876 C C . PRO A 1 491 ? -59.892 -14.777 21.389 1.00 66.13 ? 491 PRO A C 1 ATOM 3877 O O . PRO A 1 491 ? -58.757 -14.778 20.922 1.00 66.72 ? 491 PRO A O 1 ATOM 3878 C CB . PRO A 1 491 ? -59.874 -15.607 23.717 1.00 65.23 ? 491 PRO A CB 1 ATOM 3879 C CG . PRO A 1 491 ? -58.585 -16.275 23.806 1.00 64.63 ? 491 PRO A CG 1 ATOM 3880 C CD . PRO A 1 491 ? -58.744 -17.535 23.058 1.00 64.84 ? 491 PRO A CD 1 ATOM 3881 N N . VAL A 1 492 ? -60.770 -13.815 21.132 1.00 66.70 ? 492 VAL A N 1 ATOM 3882 C CA . VAL A 1 492 ? -60.372 -12.639 20.376 1.00 66.92 ? 492 VAL A CA 1 ATOM 3883 C C . VAL A 1 492 ? -59.407 -11.803 21.225 1.00 67.38 ? 492 VAL A C 1 ATOM 3884 O O . VAL A 1 492 ? -59.537 -11.751 22.445 1.00 66.99 ? 492 VAL A O 1 ATOM 3885 C CB . VAL A 1 492 ? -61.593 -11.819 19.935 1.00 66.68 ? 492 VAL A CB 1 ATOM 3886 C CG1 . VAL A 1 492 ? -61.173 -10.440 19.573 1.00 66.83 ? 492 VAL A CG1 1 ATOM 3887 C CG2 . VAL A 1 492 ? -62.263 -12.470 18.758 1.00 65.71 ? 492 VAL A CG2 1 ATOM 3888 N N . PHE A 1 493 ? -58.416 -11.191 20.574 1.00 68.24 ? 493 PHE A N 1 ATOM 3889 C CA . PHE A 1 493 ? -57.400 -10.375 21.259 1.00 68.95 ? 493 PHE A CA 1 ATOM 3890 C C . PHE A 1 493 ? -57.885 -8.952 21.387 1.00 70.07 ? 493 PHE A C 1 ATOM 3891 O O . PHE A 1 493 ? -57.853 -8.208 20.423 1.00 70.13 ? 493 PHE A O 1 ATOM 3892 C CB . PHE A 1 493 ? -56.092 -10.380 20.466 1.00 68.46 ? 493 PHE A CB 1 ATOM 3893 C CG . PHE A 1 493 ? -54.969 -9.588 21.102 1.00 67.27 ? 493 PHE A CG 1 ATOM 3894 C CD1 . PHE A 1 493 ? -54.737 -8.266 20.752 1.00 66.62 ? 493 PHE A CD1 1 ATOM 3895 C CD2 . PHE A 1 493 ? -54.119 -10.178 22.017 1.00 66.31 ? 493 PHE A CD2 1 ATOM 3896 C CE1 . PHE A 1 493 ? -53.703 -7.549 21.322 1.00 65.54 ? 493 PHE A CE1 1 ATOM 3897 C CE2 . PHE A 1 493 ? -53.079 -9.461 22.585 1.00 65.39 ? 493 PHE A CE2 1 ATOM 3898 C CZ . PHE A 1 493 ? -52.879 -8.150 22.244 1.00 65.22 ? 493 PHE A CZ 1 ATOM 3899 N N . LYS A 1 494 ? -58.342 -8.573 22.575 1.00 71.69 ? 494 LYS A N 1 ATOM 3900 C CA . LYS A 1 494 ? -58.830 -7.215 22.799 1.00 73.16 ? 494 LYS A CA 1 ATOM 3901 C C . LYS A 1 494 ? -57.686 -6.372 23.344 1.00 73.42 ? 494 LYS A C 1 ATOM 3902 O O . LYS A 1 494 ? -56.794 -6.891 24.014 1.00 73.24 ? 494 LYS A O 1 ATOM 3903 C CB . LYS A 1 494 ? -59.993 -7.229 23.795 1.00 73.92 ? 494 LYS A CB 1 ATOM 3904 C CG . LYS A 1 494 ? -61.373 -6.817 23.252 1.00 76.28 ? 494 LYS A CG 1 ATOM 3905 C CD . LYS A 1 494 ? -62.085 -5.924 24.326 1.00 81.70 ? 494 LYS A CD 1 ATOM 3906 C CE . LYS A 1 494 ? -63.507 -5.460 23.920 1.00 83.57 ? 494 LYS A CE 1 ATOM 3907 N NZ . LYS A 1 494 ? -64.611 -6.230 24.579 1.00 84.82 ? 494 LYS A NZ 1 ATOM 3908 N N . SER A 1 495 ? -57.704 -5.074 23.076 1.00 74.07 ? 495 SER A N 1 ATOM 3909 C CA . SER A 1 495 ? -56.613 -4.216 23.533 1.00 74.96 ? 495 SER A CA 1 ATOM 3910 C C . SER A 1 495 ? -56.558 -4.046 25.054 1.00 75.11 ? 495 SER A C 1 ATOM 3911 O O . SER A 1 495 ? -55.530 -3.649 25.591 1.00 74.90 ? 495 SER A O 1 ATOM 3912 C CB . SER A 1 495 ? -56.681 -2.842 22.871 1.00 75.18 ? 495 SER A CB 1 ATOM 3913 O OG . SER A 1 495 ? -57.217 -1.880 23.764 1.00 76.67 ? 495 SER A OG 1 ATOM 3914 N N . THR A 1 496 ? -57.670 -4.337 25.726 1.00 75.52 ? 496 THR A N 1 ATOM 3915 C CA . THR A 1 496 ? -57.766 -4.287 27.182 1.00 75.92 ? 496 THR A CA 1 ATOM 3916 C C . THR A 1 496 ? -57.103 -5.500 27.836 1.00 75.74 ? 496 THR A C 1 ATOM 3917 O O . THR A 1 496 ? -56.082 -5.364 28.492 1.00 75.82 ? 496 THR A O 1 ATOM 3918 C CB . THR A 1 496 ? -59.246 -4.315 27.638 1.00 76.49 ? 496 THR A CB 1 ATOM 3919 O OG1 . THR A 1 496 ? -60.122 -4.063 26.514 1.00 77.57 ? 496 THR A OG1 1 ATOM 3920 C CG2 . THR A 1 496 ? -59.494 -3.325 28.799 1.00 76.03 ? 496 THR A CG2 1 ATOM 3921 N N . GLU A 1 497 ? -57.695 -6.682 27.654 1.00 75.38 ? 497 GLU A N 1 ATOM 3922 C CA . GLU A 1 497 ? -57.286 -7.892 28.376 1.00 75.17 ? 497 GLU A CA 1 ATOM 3923 C C . GLU A 1 497 ? -56.134 -8.636 27.717 1.00 73.86 ? 497 GLU A C 1 ATOM 3924 O O . GLU A 1 497 ? -55.441 -9.401 28.376 1.00 73.78 ? 497 GLU A O 1 ATOM 3925 C CB . GLU A 1 497 ? -58.476 -8.847 28.510 1.00 76.03 ? 497 GLU A CB 1 ATOM 3926 C CG . GLU A 1 497 ? -59.801 -8.140 28.761 1.00 79.87 ? 497 GLU A CG 1 ATOM 3927 C CD . GLU A 1 497 ? -60.880 -8.496 27.727 1.00 84.92 ? 497 GLU A CD 1 ATOM 3928 O OE1 . GLU A 1 497 ? -61.792 -7.647 27.510 1.00 86.34 ? 497 GLU A OE1 1 ATOM 3929 O OE2 . GLU A 1 497 ? -60.805 -9.606 27.126 1.00 86.24 ? 497 GLU A OE2 1 ATOM 3930 N N . GLN A 1 498 ? -55.964 -8.446 26.410 1.00 72.47 ? 498 GLN A N 1 ATOM 3931 C CA . GLN A 1 498 ? -54.833 -9.015 25.671 1.00 70.91 ? 498 GLN A CA 1 ATOM 3932 C C . GLN A 1 498 ? -54.579 -10.509 25.883 1.00 69.49 ? 498 GLN A C 1 ATOM 3933 O O . GLN A 1 498 ? -53.521 -10.910 26.393 1.00 68.86 ? 498 GLN A O 1 ATOM 3934 C CB . GLN A 1 498 ? -53.570 -8.250 26.019 1.00 71.55 ? 498 GLN A CB 1 ATOM 3935 C CG . GLN A 1 498 ? -53.553 -6.832 25.496 1.00 72.38 ? 498 GLN A CG 1 ATOM 3936 C CD . GLN A 1 498 ? -52.581 -5.961 26.268 1.00 73.13 ? 498 GLN A CD 1 ATOM 3937 O OE1 . GLN A 1 498 ? -51.730 -6.460 27.021 1.00 73.25 ? 498 GLN A OE1 1 ATOM 3938 N NE2 . GLN A 1 498 ? -52.709 -4.651 26.095 1.00 73.07 ? 498 GLN A NE2 1 ATOM 3939 N N . LYS A 1 499 ? -55.543 -11.322 25.461 1.00 68.01 ? 499 LYS A N 1 ATOM 3940 C CA . LYS A 1 499 ? -55.443 -12.767 25.595 1.00 66.46 ? 499 LYS A CA 1 ATOM 3941 C C . LYS A 1 499 ? -54.810 -13.346 24.356 1.00 65.43 ? 499 LYS A C 1 ATOM 3942 O O . LYS A 1 499 ? -54.988 -12.837 23.263 1.00 64.82 ? 499 LYS A O 1 ATOM 3943 C CB . LYS A 1 499 ? -56.820 -13.398 25.795 1.00 66.33 ? 499 LYS A CB 1 ATOM 3944 C CG . LYS A 1 499 ? -57.703 -12.660 26.768 1.00 65.67 ? 499 LYS A CG 1 ATOM 3945 C CD . LYS A 1 499 ? -58.904 -13.496 27.138 1.00 64.36 ? 499 LYS A CD 1 ATOM 3946 C CE . LYS A 1 499 ? -60.004 -12.636 27.720 1.00 63.95 ? 499 LYS A CE 1 ATOM 3947 N NZ . LYS A 1 499 ? -61.164 -13.503 28.016 1.00 64.17 ? 499 LYS A NZ 1 ATOM 3948 N N . TYR A 1 500 ? -54.062 -14.419 24.552 1.00 64.48 ? 500 TYR A N 1 ATOM 3949 C CA . TYR A 1 500 ? -53.444 -15.130 23.465 1.00 63.54 ? 500 TYR A CA 1 ATOM 3950 C C . TYR A 1 500 ? -53.501 -16.617 23.796 1.00 63.86 ? 500 TYR A C 1 ATOM 3951 O O . TYR A 1 500 ? -53.727 -17.001 24.938 1.00 63.48 ? 500 TYR A O 1 ATOM 3952 C CB . TYR A 1 500 ? -52.008 -14.652 23.267 1.00 62.69 ? 500 TYR A CB 1 ATOM 3953 C CG . TYR A 1 500 ? -51.120 -14.880 24.473 1.00 60.24 ? 500 TYR A CG 1 ATOM 3954 C CD1 . TYR A 1 500 ? -51.186 -14.066 25.580 1.00 56.77 ? 500 TYR A CD1 1 ATOM 3955 C CD2 . TYR A 1 500 ? -50.199 -15.913 24.483 1.00 58.99 ? 500 TYR A CD2 1 ATOM 3956 C CE1 . TYR A 1 500 ? -50.382 -14.284 26.648 1.00 55.97 ? 500 TYR A CE1 1 ATOM 3957 C CE2 . TYR A 1 500 ? -49.391 -16.140 25.562 1.00 57.16 ? 500 TYR A CE2 1 ATOM 3958 C CZ . TYR A 1 500 ? -49.487 -15.332 26.642 1.00 55.90 ? 500 TYR A CZ 1 ATOM 3959 O OH . TYR A 1 500 ? -48.660 -15.578 27.713 1.00 55.09 ? 500 TYR A OH 1 ATOM 3960 N N . LEU A 1 501 ? -53.314 -17.452 22.789 1.00 64.30 ? 501 LEU A N 1 ATOM 3961 C CA . LEU A 1 501 ? -53.432 -18.882 22.969 1.00 65.12 ? 501 LEU A CA 1 ATOM 3962 C C . LEU A 1 501 ? -52.056 -19.457 22.840 1.00 65.80 ? 501 LEU A C 1 ATOM 3963 O O . LEU A 1 501 ? -51.342 -19.087 21.930 1.00 66.27 ? 501 LEU A O 1 ATOM 3964 C CB . LEU A 1 501 ? -54.328 -19.444 21.872 1.00 64.96 ? 501 LEU A CB 1 ATOM 3965 C CG . LEU A 1 501 ? -54.576 -20.941 21.764 1.00 64.71 ? 501 LEU A CG 1 ATOM 3966 C CD1 . LEU A 1 501 ? -55.244 -21.480 22.996 1.00 64.18 ? 501 LEU A CD1 1 ATOM 3967 C CD2 . LEU A 1 501 ? -55.460 -21.166 20.554 1.00 65.03 ? 501 LEU A CD2 1 ATOM 3968 N N . THR A 1 502 ? -51.658 -20.336 23.744 1.00 66.80 ? 502 THR A N 1 ATOM 3969 C CA . THR A 1 502 ? -50.357 -20.971 23.616 1.00 68.10 ? 502 THR A CA 1 ATOM 3970 C C . THR A 1 502 ? -50.509 -22.211 22.744 1.00 69.14 ? 502 THR A C 1 ATOM 3971 O O . THR A 1 502 ? -51.503 -22.924 22.858 1.00 69.64 ? 502 THR A O 1 ATOM 3972 C CB . THR A 1 502 ? -49.746 -21.352 24.980 1.00 68.14 ? 502 THR A CB 1 ATOM 3973 O OG1 . THR A 1 502 ? -50.417 -22.491 25.525 1.00 68.14 ? 502 THR A OG1 1 ATOM 3974 C CG2 . THR A 1 502 ? -49.823 -20.190 25.974 1.00 68.17 ? 502 THR A CG2 1 ATOM 3975 N N . LEU A 1 503 ? -49.549 -22.457 21.853 1.00 70.06 ? 503 LEU A N 1 ATOM 3976 C CA . LEU A 1 503 ? -49.592 -23.633 20.995 1.00 70.87 ? 503 LEU A CA 1 ATOM 3977 C C . LEU A 1 503 ? -48.478 -24.594 21.383 1.00 72.42 ? 503 LEU A C 1 ATOM 3978 O O . LEU A 1 503 ? -47.306 -24.248 21.329 1.00 72.51 ? 503 LEU A O 1 ATOM 3979 C CB . LEU A 1 503 ? -49.411 -23.226 19.546 1.00 70.23 ? 503 LEU A CB 1 ATOM 3980 C CG . LEU A 1 503 ? -50.457 -22.312 18.945 1.00 68.88 ? 503 LEU A CG 1 ATOM 3981 C CD1 . LEU A 1 503 ? -50.259 -22.209 17.448 1.00 66.38 ? 503 LEU A CD1 1 ATOM 3982 C CD2 . LEU A 1 503 ? -51.812 -22.864 19.264 1.00 68.65 ? 503 LEU A CD2 1 ATOM 3983 N N . ASN A 1 504 ? -48.843 -25.808 21.769 1.00 74.43 ? 504 ASN A N 1 ATOM 3984 C CA . ASN A 1 504 ? -47.859 -26.823 22.142 1.00 76.28 ? 504 ASN A CA 1 ATOM 3985 C C . ASN A 1 504 ? -48.491 -28.220 22.190 1.00 77.40 ? 504 ASN A C 1 ATOM 3986 O O . ASN A 1 504 ? -49.703 -28.352 22.081 1.00 77.44 ? 504 ASN A O 1 ATOM 3987 C CB . ASN A 1 504 ? -47.228 -26.467 23.481 1.00 76.28 ? 504 ASN A CB 1 ATOM 3988 C CG . ASN A 1 504 ? -48.217 -26.528 24.611 1.00 77.15 ? 504 ASN A CG 1 ATOM 3989 O OD1 . ASN A 1 504 ? -48.562 -27.604 25.092 1.00 77.36 ? 504 ASN A OD1 1 ATOM 3990 N ND2 . ASN A 1 504 ? -48.695 -25.370 25.035 1.00 78.64 ? 504 ASN A ND2 1 ATOM 3991 N N . THR A 1 505 ? -47.675 -29.255 22.370 1.00 79.04 ? 505 THR A N 1 ATOM 3992 C CA . THR A 1 505 ? -48.156 -30.633 22.298 1.00 80.53 ? 505 THR A CA 1 ATOM 3993 C C . THR A 1 505 ? -48.943 -31.081 23.513 1.00 81.90 ? 505 THR A C 1 ATOM 3994 O O . THR A 1 505 ? -49.807 -31.946 23.405 1.00 82.16 ? 505 THR A O 1 ATOM 3995 C CB . THR A 1 505 ? -47.018 -31.607 22.200 1.00 80.46 ? 505 THR A CB 1 ATOM 3996 O OG1 . THR A 1 505 ? -46.292 -31.571 23.436 1.00 80.26 ? 505 THR A OG1 1 ATOM 3997 C CG2 . THR A 1 505 ? -46.123 -31.265 21.019 1.00 80.16 ? 505 THR A CG2 1 ATOM 3998 N N . GLU A 1 506 ? -48.627 -30.536 24.681 1.00 83.53 ? 506 GLU A N 1 ATOM 3999 C CA . GLU A 1 506 ? -49.388 -30.877 25.876 1.00 85.09 ? 506 GLU A CA 1 ATOM 4000 C C . GLU A 1 506 ? -50.756 -30.207 25.852 1.00 85.30 ? 506 GLU A C 1 ATOM 4001 O O . GLU A 1 506 ? -51.640 -30.600 25.096 1.00 85.60 ? 506 GLU A O 1 ATOM 4002 C CB . GLU A 1 506 ? -48.624 -30.497 27.141 1.00 85.55 ? 506 GLU A CB 1 ATOM 4003 C CG . GLU A 1 506 ? -47.211 -31.064 27.194 1.00 88.82 ? 506 GLU A CG 1 ATOM 4004 C CD . GLU A 1 506 ? -46.133 -29.980 27.150 1.00 93.07 ? 506 GLU A CD 1 ATOM 4005 O OE1 . GLU A 1 506 ? -46.464 -28.798 27.429 1.00 95.56 ? 506 GLU A OE1 1 ATOM 4006 O OE2 . GLU A 1 506 ? -44.958 -30.308 26.846 1.00 93.87 ? 506 GLU A OE2 1 ATOM 4007 N N . SER A 1 507 ? -50.937 -29.193 26.682 1.00 85.64 ? 507 SER A N 1 ATOM 4008 C CA . SER A 1 507 ? -52.202 -28.455 26.686 1.00 85.55 ? 507 SER A CA 1 ATOM 4009 C C . SER A 1 507 ? -51.999 -27.047 26.134 1.00 84.86 ? 507 SER A C 1 ATOM 4010 O O . SER A 1 507 ? -51.048 -26.354 26.503 1.00 84.99 ? 507 SER A O 1 ATOM 4011 C CB . SER A 1 507 ? -52.780 -28.371 28.106 1.00 85.92 ? 507 SER A CB 1 ATOM 4012 O OG . SER A 1 507 ? -51.965 -27.543 28.944 1.00 86.50 ? 507 SER A OG 1 ATOM 4013 N N . THR A 1 508 ? -52.890 -26.630 25.253 1.00 83.70 ? 508 THR A N 1 ATOM 4014 C CA . THR A 1 508 ? -52.902 -25.253 24.821 1.00 82.93 ? 508 THR A CA 1 ATOM 4015 C C . THR A 1 508 ? -53.684 -24.457 25.858 1.00 82.10 ? 508 THR A C 1 ATOM 4016 O O . THR A 1 508 ? -54.807 -24.828 26.158 1.00 82.37 ? 508 THR A O 1 ATOM 4017 C CB . THR A 1 508 ? -53.635 -25.117 23.500 1.00 83.13 ? 508 THR A CB 1 ATOM 4018 O OG1 . THR A 1 508 ? -55.033 -25.349 23.721 1.00 83.24 ? 508 THR A OG1 1 ATOM 4019 C CG2 . THR A 1 508 ? -53.072 -26.122 22.458 1.00 83.51 ? 508 THR A CG2 1 ATOM 4020 N N . ARG A 1 509 ? -53.113 -23.370 26.391 1.00 80.72 ? 509 ARG A N 1 ATOM 4021 C CA . ARG A 1 509 ? -53.786 -22.535 27.396 1.00 79.19 ? 509 ARG A CA 1 ATOM 4022 C C . ARG A 1 509 ? -54.072 -21.112 26.921 1.00 77.74 ? 509 ARG A C 1 ATOM 4023 O O . ARG A 1 509 ? -53.416 -20.611 26.020 1.00 77.62 ? 509 ARG A O 1 ATOM 4024 C CB . ARG A 1 509 ? -52.952 -22.464 28.666 1.00 79.58 ? 509 ARG A CB 1 ATOM 4025 C CG . ARG A 1 509 ? -52.784 -23.779 29.355 1.00 81.48 ? 509 ARG A CG 1 ATOM 4026 C CD . ARG A 1 509 ? -51.926 -23.594 30.576 1.00 86.62 ? 509 ARG A CD 1 ATOM 4027 N NE . ARG A 1 509 ? -51.511 -24.863 31.178 1.00 91.04 ? 509 ARG A NE 1 ATOM 4028 C CZ . ARG A 1 509 ? -52.333 -25.698 31.811 1.00 92.42 ? 509 ARG A CZ 1 ATOM 4029 N NH1 . ARG A 1 509 ? -53.624 -25.403 31.911 1.00 93.22 ? 509 ARG A NH1 1 ATOM 4030 N NH2 . ARG A 1 509 ? -51.865 -26.827 32.336 1.00 92.63 ? 509 ARG A NH2 1 ATOM 4031 N N . ILE A 1 510 ? -55.057 -20.466 27.542 1.00 76.09 ? 510 ILE A N 1 ATOM 4032 C CA . ILE A 1 510 ? -55.368 -19.061 27.284 1.00 74.29 ? 510 ILE A CA 1 ATOM 4033 C C . ILE A 1 510 ? -54.690 -18.209 28.339 1.00 73.42 ? 510 ILE A C 1 ATOM 4034 O O . ILE A 1 510 ? -54.869 -18.431 29.530 1.00 73.09 ? 510 ILE A O 1 ATOM 4035 C CB . ILE A 1 510 ? -56.857 -18.770 27.409 1.00 74.06 ? 510 ILE A CB 1 ATOM 4036 C CG1 . ILE A 1 510 ? -57.667 -19.593 26.424 1.00 74.11 ? 510 ILE A CG1 1 ATOM 4037 C CG2 . ILE A 1 510 ? -57.109 -17.345 27.132 1.00 73.73 ? 510 ILE A CG2 1 ATOM 4038 C CD1 . ILE A 1 510 ? -57.516 -19.140 25.027 1.00 75.36 ? 510 ILE A CD1 1 ATOM 4039 N N . MET A 1 511 ? -53.915 -17.225 27.906 1.00 72.45 ? 511 MET A N 1 ATOM 4040 C CA . MET A 1 511 ? -53.170 -16.406 28.839 1.00 71.37 ? 511 MET A CA 1 ATOM 4041 C C . MET A 1 511 ? -53.247 -14.943 28.471 1.00 70.65 ? 511 MET A C 1 ATOM 4042 O O . MET A 1 511 ? -53.704 -14.598 27.370 1.00 70.49 ? 511 MET A O 1 ATOM 4043 C CB . MET A 1 511 ? -51.740 -16.877 28.882 1.00 71.40 ? 511 MET A CB 1 ATOM 4044 C CG . MET A 1 511 ? -51.681 -18.335 29.159 1.00 72.52 ? 511 MET A CG 1 ATOM 4045 S SD . MET A 1 511 ? -50.392 -18.651 30.342 1.00 75.87 ? 511 MET A SD 1 ATOM 4046 C CE . MET A 1 511 ? -48.962 -18.819 29.240 1.00 74.93 ? 511 MET A CE 1 ATOM 4047 N N . THR A 1 512 ? -52.812 -14.082 29.394 1.00 69.52 ? 512 THR A N 1 ATOM 4048 C CA . THR A 1 512 ? -52.931 -12.646 29.186 1.00 68.75 ? 512 THR A CA 1 ATOM 4049 C C . THR A 1 512 ? -51.604 -11.914 29.138 1.00 68.24 ? 512 THR A C 1 ATOM 4050 O O . THR A 1 512 ? -50.638 -12.311 29.770 1.00 67.72 ? 512 THR A O 1 ATOM 4051 C CB . THR A 1 512 ? -53.775 -11.977 30.287 1.00 68.68 ? 512 THR A CB 1 ATOM 4052 O OG1 . THR A 1 512 ? -53.354 -12.463 31.548 1.00 69.34 ? 512 THR A OG1 1 ATOM 4053 C CG2 . THR A 1 512 ? -55.219 -12.314 30.150 1.00 68.45 ? 512 THR A CG2 1 ATOM 4054 N N . LYS A 1 513 ? -51.576 -10.831 28.374 1.00 68.04 ? 513 LYS A N 1 ATOM 4055 C CA . LYS A 1 513 ? -50.520 -9.859 28.514 1.00 67.99 ? 513 LYS A CA 1 ATOM 4056 C C . LYS A 1 513 ? -49.148 -10.460 28.348 1.00 67.65 ? 513 LYS A C 1 ATOM 4057 O O . LYS A 1 513 ? -48.314 -10.336 29.236 1.00 67.46 ? 513 LYS A O 1 ATOM 4058 C CB . LYS A 1 513 ? -50.626 -9.200 29.888 1.00 68.27 ? 513 LYS A CB 1 ATOM 4059 C CG . LYS A 1 513 ? -51.706 -8.156 29.910 1.00 69.31 ? 513 LYS A CG 1 ATOM 4060 C CD . LYS A 1 513 ? -52.299 -7.914 31.284 1.00 70.54 ? 513 LYS A CD 1 ATOM 4061 C CE . LYS A 1 513 ? -53.612 -7.112 31.146 1.00 71.60 ? 513 LYS A CE 1 ATOM 4062 N NZ . LYS A 1 513 ? -53.876 -6.188 32.289 1.00 72.88 ? 513 LYS A NZ 1 ATOM 4063 N N . LEU A 1 514 ? -48.918 -11.091 27.201 1.00 67.64 ? 514 LEU A N 1 ATOM 4064 C CA . LEU A 1 514 ? -47.625 -11.658 26.863 1.00 67.46 ? 514 LEU A CA 1 ATOM 4065 C C . LEU A 1 514 ? -46.503 -10.649 27.099 1.00 68.01 ? 514 LEU A C 1 ATOM 4066 O O . LEU A 1 514 ? -46.576 -9.513 26.632 1.00 68.15 ? 514 LEU A O 1 ATOM 4067 C CB . LEU A 1 514 ? -47.625 -12.096 25.401 1.00 66.93 ? 514 LEU A CB 1 ATOM 4068 C CG . LEU A 1 514 ? -46.362 -12.824 24.948 1.00 65.53 ? 514 LEU A CG 1 ATOM 4069 C CD1 . LEU A 1 514 ? -46.243 -14.131 25.685 1.00 64.03 ? 514 LEU A CD1 1 ATOM 4070 C CD2 . LEU A 1 514 ? -46.361 -13.063 23.452 1.00 64.08 ? 514 LEU A CD2 1 ATOM 4071 N N . ARG A 1 515 ? -45.472 -11.061 27.830 1.00 68.38 ? 515 ARG A N 1 ATOM 4072 C CA . ARG A 1 515 ? -44.293 -10.229 28.041 1.00 68.95 ? 515 ARG A CA 1 ATOM 4073 C C . ARG A 1 515 ? -44.607 -8.770 28.275 1.00 69.20 ? 515 ARG A C 1 ATOM 4074 O O . ARG A 1 515 ? -44.044 -7.904 27.600 1.00 69.01 ? 515 ARG A O 1 ATOM 4075 C CB . ARG A 1 515 ? -43.410 -10.317 26.828 1.00 69.26 ? 515 ARG A CB 1 ATOM 4076 C CG . ARG A 1 515 ? -42.871 -11.688 26.588 1.00 70.98 ? 515 ARG A CG 1 ATOM 4077 C CD . ARG A 1 515 ? -41.546 -11.868 27.277 1.00 73.86 ? 515 ARG A CD 1 ATOM 4078 N NE . ARG A 1 515 ? -40.593 -12.347 26.297 1.00 76.54 ? 515 ARG A NE 1 ATOM 4079 C CZ . ARG A 1 515 ? -40.674 -13.541 25.724 1.00 79.12 ? 515 ARG A CZ 1 ATOM 4080 N NH1 . ARG A 1 515 ? -39.763 -13.902 24.820 1.00 80.21 ? 515 ARG A NH1 1 ATOM 4081 N NH2 . ARG A 1 515 ? -41.662 -14.371 26.062 1.00 79.21 ? 515 ARG A NH2 1 ATOM 4082 N N . ALA A 1 516 ? -45.490 -8.506 29.242 1.00 69.74 ? 516 ALA A N 1 ATOM 4083 C CA . ALA A 1 516 ? -45.981 -7.157 29.545 1.00 69.98 ? 516 ALA A CA 1 ATOM 4084 C C . ALA A 1 516 ? -44.874 -6.286 30.106 1.00 70.29 ? 516 ALA A C 1 ATOM 4085 O O . ALA A 1 516 ? -44.615 -5.190 29.601 1.00 70.49 ? 516 ALA A O 1 ATOM 4086 C CB . ALA A 1 516 ? -47.139 -7.226 30.514 1.00 69.79 ? 516 ALA A CB 1 ATOM 4087 N N . GLN A 1 517 ? -44.231 -6.790 31.151 1.00 70.56 ? 517 GLN A N 1 ATOM 4088 C CA . GLN A 1 517 ? -43.059 -6.168 31.730 1.00 71.19 ? 517 GLN A CA 1 ATOM 4089 C C . GLN A 1 517 ? -42.038 -5.658 30.685 1.00 70.60 ? 517 GLN A C 1 ATOM 4090 O O . GLN A 1 517 ? -41.751 -4.464 30.610 1.00 70.58 ? 517 GLN A O 1 ATOM 4091 C CB . GLN A 1 517 ? -42.373 -7.190 32.638 1.00 72.19 ? 517 GLN A CB 1 ATOM 4092 C CG . GLN A 1 517 ? -41.213 -6.622 33.433 1.00 75.87 ? 517 GLN A CG 1 ATOM 4093 C CD . GLN A 1 517 ? -41.708 -5.810 34.618 1.00 81.21 ? 517 GLN A CD 1 ATOM 4094 O OE1 . GLN A 1 517 ? -42.111 -6.385 35.636 1.00 83.37 ? 517 GLN A OE1 1 ATOM 4095 N NE2 . GLN A 1 517 ? -41.704 -4.467 34.489 1.00 82.45 ? 517 GLN A NE2 1 ATOM 4096 N N . GLN A 1 518 ? -41.492 -6.577 29.887 1.00 69.77 ? 518 GLN A N 1 ATOM 4097 C CA . GLN A 1 518 ? -40.466 -6.267 28.914 1.00 68.48 ? 518 GLN A CA 1 ATOM 4098 C C . GLN A 1 518 ? -40.966 -5.353 27.830 1.00 68.04 ? 518 GLN A C 1 ATOM 4099 O O . GLN A 1 518 ? -40.288 -4.413 27.468 1.00 68.01 ? 518 GLN A O 1 ATOM 4100 C CB . GLN A 1 518 ? -39.939 -7.539 28.279 1.00 68.33 ? 518 GLN A CB 1 ATOM 4101 C CG . GLN A 1 518 ? -39.402 -8.537 29.269 1.00 68.61 ? 518 GLN A CG 1 ATOM 4102 C CD . GLN A 1 518 ? -40.464 -9.459 29.826 1.00 69.38 ? 518 GLN A CD 1 ATOM 4103 O OE1 . GLN A 1 518 ? -40.171 -10.579 30.211 1.00 70.34 ? 518 GLN A OE1 1 ATOM 4104 N NE2 . GLN A 1 518 ? -41.703 -8.997 29.861 1.00 69.65 ? 518 GLN A NE2 1 ATOM 4105 N N . CYS A 1 519 ? -42.143 -5.608 27.291 1.00 67.59 ? 519 CYS A N 1 ATOM 4106 C CA . CYS A 1 519 ? -42.549 -4.786 26.165 1.00 67.53 ? 519 CYS A CA 1 ATOM 4107 C C . CYS A 1 519 ? -42.862 -3.359 26.549 1.00 67.73 ? 519 CYS A C 1 ATOM 4108 O O . CYS A 1 519 ? -42.889 -2.476 25.698 1.00 67.51 ? 519 CYS A O 1 ATOM 4109 C CB . CYS A 1 519 ? -43.702 -5.403 25.387 1.00 67.30 ? 519 CYS A CB 1 ATOM 4110 S SG . CYS A 1 519 ? -43.232 -6.836 24.383 1.00 66.72 ? 519 CYS A SG 1 ATOM 4111 N N . ARG A 1 520 ? -43.103 -3.121 27.827 1.00 68.21 ? 520 ARG A N 1 ATOM 4112 C CA . ARG A 1 520 ? -43.313 -1.753 28.258 1.00 68.78 ? 520 ARG A CA 1 ATOM 4113 C C . ARG A 1 520 ? -42.034 -0.993 27.937 1.00 68.28 ? 520 ARG A C 1 ATOM 4114 O O . ARG A 1 520 ? -42.042 0.054 27.299 1.00 67.81 ? 520 ARG A O 1 ATOM 4115 C CB . ARG A 1 520 ? -43.605 -1.723 29.749 1.00 69.20 ? 520 ARG A CB 1 ATOM 4116 C CG . ARG A 1 520 ? -44.202 -0.415 30.267 1.00 72.26 ? 520 ARG A CG 1 ATOM 4117 C CD . ARG A 1 520 ? -44.965 -0.625 31.608 1.00 77.70 ? 520 ARG A CD 1 ATOM 4118 N NE . ARG A 1 520 ? -46.100 -1.554 31.464 1.00 81.90 ? 520 ARG A NE 1 ATOM 4119 C CZ . ARG A 1 520 ? -46.190 -2.757 32.045 1.00 84.50 ? 520 ARG A CZ 1 ATOM 4120 N NH1 . ARG A 1 520 ? -47.261 -3.525 31.830 1.00 85.48 ? 520 ARG A NH1 1 ATOM 4121 N NH2 . ARG A 1 520 ? -45.216 -3.198 32.846 1.00 85.78 ? 520 ARG A NH2 1 ATOM 4122 N N . PHE A 1 521 ? -40.927 -1.577 28.373 1.00 68.23 ? 521 PHE A N 1 ATOM 4123 C CA . PHE A 1 521 ? -39.589 -1.068 28.128 1.00 68.03 ? 521 PHE A CA 1 ATOM 4124 C C . PHE A 1 521 ? -39.295 -0.835 26.655 1.00 68.10 ? 521 PHE A C 1 ATOM 4125 O O . PHE A 1 521 ? -38.873 0.244 26.270 1.00 67.91 ? 521 PHE A O 1 ATOM 4126 C CB . PHE A 1 521 ? -38.578 -2.053 28.699 1.00 68.08 ? 521 PHE A CB 1 ATOM 4127 C CG . PHE A 1 521 ? -37.171 -1.732 28.358 1.00 68.14 ? 521 PHE A CG 1 ATOM 4128 C CD1 . PHE A 1 521 ? -36.398 -0.987 29.217 1.00 68.18 ? 521 PHE A CD1 1 ATOM 4129 C CD2 . PHE A 1 521 ? -36.621 -2.171 27.177 1.00 68.86 ? 521 PHE A CD2 1 ATOM 4130 C CE1 . PHE A 1 521 ? -35.109 -0.694 28.907 1.00 68.98 ? 521 PHE A CE1 1 ATOM 4131 C CE2 . PHE A 1 521 ? -35.326 -1.875 26.850 1.00 68.57 ? 521 PHE A CE2 1 ATOM 4132 C CZ . PHE A 1 521 ? -34.567 -1.141 27.713 1.00 69.53 ? 521 PHE A CZ 1 ATOM 4133 N N . TRP A 1 522 ? -39.513 -1.847 25.827 1.00 68.40 ? 522 TRP A N 1 ATOM 4134 C CA . TRP A 1 522 ? -39.249 -1.713 24.413 1.00 68.84 ? 522 TRP A CA 1 ATOM 4135 C C . TRP A 1 522 ? -40.178 -0.734 23.722 1.00 69.88 ? 522 TRP A C 1 ATOM 4136 O O . TRP A 1 522 ? -39.773 -0.006 22.828 1.00 69.86 ? 522 TRP A O 1 ATOM 4137 C CB . TRP A 1 522 ? -39.338 -3.064 23.753 1.00 68.41 ? 522 TRP A CB 1 ATOM 4138 C CG . TRP A 1 522 ? -38.247 -3.934 24.196 1.00 67.84 ? 522 TRP A CG 1 ATOM 4139 C CD1 . TRP A 1 522 ? -38.338 -5.046 24.992 1.00 67.29 ? 522 TRP A CD1 1 ATOM 4140 C CD2 . TRP A 1 522 ? -36.864 -3.771 23.892 1.00 67.54 ? 522 TRP A CD2 1 ATOM 4141 N NE1 . TRP A 1 522 ? -37.092 -5.589 25.195 1.00 66.24 ? 522 TRP A NE1 1 ATOM 4142 C CE2 . TRP A 1 522 ? -36.168 -4.818 24.536 1.00 67.35 ? 522 TRP A CE2 1 ATOM 4143 C CE3 . TRP A 1 522 ? -36.142 -2.843 23.131 1.00 67.33 ? 522 TRP A CE3 1 ATOM 4144 C CZ2 . TRP A 1 522 ? -34.780 -4.955 24.443 1.00 67.75 ? 522 TRP A CZ2 1 ATOM 4145 C CZ3 . TRP A 1 522 ? -34.771 -2.981 23.037 1.00 67.29 ? 522 TRP A CZ3 1 ATOM 4146 C CH2 . TRP A 1 522 ? -34.101 -4.030 23.687 1.00 67.79 ? 522 TRP A CH2 1 ATOM 4147 N N . THR A 1 523 ? -41.431 -0.707 24.143 1.00 71.37 ? 523 THR A N 1 ATOM 4148 C CA . THR A 1 523 ? -42.407 0.153 23.497 1.00 72.83 ? 523 THR A CA 1 ATOM 4149 C C . THR A 1 523 ? -42.438 1.575 24.030 1.00 73.49 ? 523 THR A C 1 ATOM 4150 O O . THR A 1 523 ? -42.576 2.508 23.258 1.00 73.47 ? 523 THR A O 1 ATOM 4151 C CB . THR A 1 523 ? -43.808 -0.447 23.591 1.00 72.92 ? 523 THR A CB 1 ATOM 4152 O OG1 . THR A 1 523 ? -43.839 -1.664 22.832 1.00 74.17 ? 523 THR A OG1 1 ATOM 4153 C CG2 . THR A 1 523 ? -44.851 0.530 23.049 1.00 73.13 ? 523 THR A CG2 1 ATOM 4154 N N . SER A 1 524 ? -42.320 1.744 25.343 1.00 74.62 ? 524 SER A N 1 ATOM 4155 C CA . SER A 1 524 ? -42.494 3.061 25.931 1.00 75.58 ? 524 SER A CA 1 ATOM 4156 C C . SER A 1 524 ? -41.190 3.767 26.114 1.00 76.39 ? 524 SER A C 1 ATOM 4157 O O . SER A 1 524 ? -41.035 4.908 25.703 1.00 77.03 ? 524 SER A O 1 ATOM 4158 C CB . SER A 1 524 ? -43.179 2.954 27.266 1.00 75.52 ? 524 SER A CB 1 ATOM 4159 O OG . SER A 1 524 ? -44.497 2.506 27.070 1.00 76.57 ? 524 SER A OG 1 ATOM 4160 N N . PHE A 1 525 ? -40.239 3.090 26.731 1.00 77.04 ? 525 PHE A N 1 ATOM 4161 C CA . PHE A 1 525 ? -38.976 3.721 27.031 1.00 77.78 ? 525 PHE A CA 1 ATOM 4162 C C . PHE A 1 525 ? -37.962 3.782 25.869 1.00 77.81 ? 525 PHE A C 1 ATOM 4163 O O . PHE A 1 525 ? -37.539 4.855 25.457 1.00 77.96 ? 525 PHE A O 1 ATOM 4164 C CB . PHE A 1 525 ? -38.357 3.034 28.231 1.00 78.10 ? 525 PHE A CB 1 ATOM 4165 C CG . PHE A 1 525 ? -37.039 3.580 28.596 1.00 80.62 ? 525 PHE A CG 1 ATOM 4166 C CD1 . PHE A 1 525 ? -36.075 2.774 29.170 1.00 83.13 ? 525 PHE A CD1 1 ATOM 4167 C CD2 . PHE A 1 525 ? -36.752 4.912 28.346 1.00 82.93 ? 525 PHE A CD2 1 ATOM 4168 C CE1 . PHE A 1 525 ? -34.843 3.297 29.514 1.00 84.96 ? 525 PHE A CE1 1 ATOM 4169 C CE2 . PHE A 1 525 ? -35.540 5.442 28.672 1.00 84.72 ? 525 PHE A CE2 1 ATOM 4170 C CZ . PHE A 1 525 ? -34.573 4.636 29.260 1.00 85.80 ? 525 PHE A CZ 1 ATOM 4171 N N . PHE A 1 526 ? -37.581 2.632 25.338 1.00 77.80 ? 526 PHE A N 1 ATOM 4172 C CA . PHE A 1 526 ? -36.444 2.551 24.437 1.00 77.72 ? 526 PHE A CA 1 ATOM 4173 C C . PHE A 1 526 ? -36.456 3.425 23.159 1.00 78.49 ? 526 PHE A C 1 ATOM 4174 O O . PHE A 1 526 ? -35.385 3.809 22.684 1.00 78.78 ? 526 PHE A O 1 ATOM 4175 C CB . PHE A 1 526 ? -36.181 1.090 24.079 1.00 77.33 ? 526 PHE A CB 1 ATOM 4176 C CG . PHE A 1 526 ? -34.838 0.849 23.462 1.00 75.68 ? 526 PHE A CG 1 ATOM 4177 C CD1 . PHE A 1 526 ? -33.711 0.751 24.256 1.00 74.06 ? 526 PHE A CD1 1 ATOM 4178 C CD2 . PHE A 1 526 ? -34.705 0.714 22.093 1.00 74.38 ? 526 PHE A CD2 1 ATOM 4179 C CE1 . PHE A 1 526 ? -32.479 0.535 23.705 1.00 72.52 ? 526 PHE A CE1 1 ATOM 4180 C CE2 . PHE A 1 526 ? -33.469 0.488 21.534 1.00 73.46 ? 526 PHE A CE2 1 ATOM 4181 C CZ . PHE A 1 526 ? -32.356 0.403 22.345 1.00 72.83 ? 526 PHE A CZ 1 ATOM 4182 N N . PRO A 1 527 ? -37.641 3.714 22.572 1.00 78.95 ? 527 PRO A N 1 ATOM 4183 C CA . PRO A 1 527 ? -37.594 4.520 21.347 1.00 79.29 ? 527 PRO A CA 1 ATOM 4184 C C . PRO A 1 527 ? -37.076 5.914 21.642 1.00 79.90 ? 527 PRO A C 1 ATOM 4185 O O . PRO A 1 527 ? -36.768 6.679 20.739 1.00 79.82 ? 527 PRO A O 1 ATOM 4186 C CB . PRO A 1 527 ? -39.055 4.586 20.912 1.00 78.95 ? 527 PRO A CB 1 ATOM 4187 C CG . PRO A 1 527 ? -39.669 3.381 21.493 1.00 79.19 ? 527 PRO A CG 1 ATOM 4188 C CD . PRO A 1 527 ? -39.001 3.220 22.834 1.00 79.02 ? 527 PRO A CD 1 ATOM 4189 N N . LYS A 1 528 ? -36.959 6.223 22.923 1.00 80.75 ? 528 LYS A N 1 ATOM 4190 C CA . LYS A 1 528 ? -36.540 7.540 23.339 1.00 81.49 ? 528 LYS A CA 1 ATOM 4191 C C . LYS A 1 528 ? -35.023 7.674 23.520 1.00 81.94 ? 528 LYS A C 1 ATOM 4192 O O . LYS A 1 528 ? -34.478 8.758 23.324 1.00 82.34 ? 528 LYS A O 1 ATOM 4193 C CB . LYS A 1 528 ? -37.312 7.958 24.591 1.00 81.43 ? 528 LYS A CB 1 ATOM 4194 C CG . LYS A 1 528 ? -38.766 8.295 24.276 1.00 81.88 ? 528 LYS A CG 1 ATOM 4195 C CD . LYS A 1 528 ? -39.735 7.824 25.348 1.00 82.43 ? 528 LYS A CD 1 ATOM 4196 C CE . LYS A 1 528 ? -39.673 8.692 26.579 1.00 82.73 ? 528 LYS A CE 1 ATOM 4197 N NZ . LYS A 1 528 ? -40.632 8.214 27.595 1.00 82.50 ? 528 LYS A NZ 1 ATOM 4198 N N . VAL A 1 529 ? -34.336 6.585 23.859 1.00 82.21 ? 529 VAL A N 1 ATOM 4199 C CA . VAL A 1 529 ? -32.874 6.637 23.997 1.00 82.57 ? 529 VAL A CA 1 ATOM 4200 C C . VAL A 1 529 ? -32.152 6.878 22.659 1.00 82.87 ? 529 VAL A C 1 ATOM 4201 O O . VAL A 1 529 ? -32.766 6.940 21.581 1.00 82.90 ? 529 VAL A O 1 ATOM 4202 C CB . VAL A 1 529 ? -32.294 5.361 24.653 1.00 82.48 ? 529 VAL A CB 1 ATOM 4203 C CG1 . VAL A 1 529 ? -33.075 4.989 25.897 1.00 82.28 ? 529 VAL A CG1 1 ATOM 4204 C CG2 . VAL A 1 529 ? -32.292 4.223 23.664 1.00 82.49 ? 529 VAL A CG2 1 ATOM 4205 O OXT . VAL A 1 529 ? -30.922 7.021 22.643 1.00 83.06 ? 529 VAL A OXT 1 ATOM 4206 N N . ILE B 1 4 ? -38.861 -15.086 81.497 1.00 90.86 ? 4 ILE B N 1 ATOM 4207 C CA . ILE B 1 4 ? -39.947 -14.324 80.805 1.00 90.18 ? 4 ILE B CA 1 ATOM 4208 C C . ILE B 1 4 ? -41.346 -14.956 81.041 1.00 89.46 ? 4 ILE B C 1 ATOM 4209 O O . ILE B 1 4 ? -41.684 -16.020 80.500 1.00 89.44 ? 4 ILE B O 1 ATOM 4210 C CB . ILE B 1 4 ? -39.596 -14.098 79.298 1.00 90.37 ? 4 ILE B CB 1 ATOM 4211 C CG1 . ILE B 1 4 ? -40.103 -12.745 78.813 1.00 90.68 ? 4 ILE B CG1 1 ATOM 4212 C CG2 . ILE B 1 4 ? -40.112 -15.216 78.432 1.00 90.16 ? 4 ILE B CG2 1 ATOM 4213 C CD1 . ILE B 1 4 ? -39.437 -12.270 77.552 1.00 91.80 ? 4 ILE B CD1 1 ATOM 4214 N N . ILE B 1 5 ? -42.143 -14.284 81.872 1.00 88.34 ? 5 ILE B N 1 ATOM 4215 C CA . ILE B 1 5 ? -43.408 -14.828 82.363 1.00 87.20 ? 5 ILE B CA 1 ATOM 4216 C C . ILE B 1 5 ? -44.606 -14.067 81.804 1.00 86.66 ? 5 ILE B C 1 ATOM 4217 O O . ILE B 1 5 ? -44.600 -12.837 81.739 1.00 86.29 ? 5 ILE B O 1 ATOM 4218 C CB . ILE B 1 5 ? -43.471 -14.811 83.934 1.00 87.09 ? 5 ILE B CB 1 ATOM 4219 C CG1 . ILE B 1 5 ? -42.459 -15.787 84.544 1.00 86.63 ? 5 ILE B CG1 1 ATOM 4220 C CG2 . ILE B 1 5 ? -44.877 -15.126 84.447 1.00 86.57 ? 5 ILE B CG2 1 ATOM 4221 C CD1 . ILE B 1 5 ? -41.029 -15.292 84.498 1.00 86.05 ? 5 ILE B CD1 1 ATOM 4222 N N . ILE B 1 6 ? -45.634 -14.810 81.400 1.00 86.16 ? 6 ILE B N 1 ATOM 4223 C CA . ILE B 1 6 ? -46.905 -14.205 81.017 1.00 85.51 ? 6 ILE B CA 1 ATOM 4224 C C . ILE B 1 6 ? -48.040 -14.627 81.952 1.00 85.37 ? 6 ILE B C 1 ATOM 4225 O O . ILE B 1 6 ? -48.151 -15.795 82.336 1.00 85.01 ? 6 ILE B O 1 ATOM 4226 C CB . ILE B 1 6 ? -47.263 -14.527 79.565 1.00 85.20 ? 6 ILE B CB 1 ATOM 4227 C CG1 . ILE B 1 6 ? -46.119 -14.121 78.658 1.00 84.30 ? 6 ILE B CG1 1 ATOM 4228 C CG2 . ILE B 1 6 ? -48.492 -13.747 79.152 1.00 85.15 ? 6 ILE B CG2 1 ATOM 4229 C CD1 . ILE B 1 6 ? -45.996 -12.620 78.554 1.00 84.06 ? 6 ILE B CD1 1 ATOM 4230 N N . ALA B 1 7 ? -48.875 -13.659 82.312 1.00 85.36 ? 7 ALA B N 1 ATOM 4231 C CA . ALA B 1 7 ? -49.945 -13.881 83.273 1.00 85.82 ? 7 ALA B CA 1 ATOM 4232 C C . ALA B 1 7 ? -51.260 -14.235 82.581 1.00 86.05 ? 7 ALA B C 1 ATOM 4233 O O . ALA B 1 7 ? -52.100 -13.355 82.361 1.00 86.19 ? 7 ALA B O 1 ATOM 4234 C CB . ALA B 1 7 ? -50.128 -12.639 84.164 1.00 85.47 ? 7 ALA B CB 1 ATOM 4235 N N . THR B 1 8 ? -51.451 -15.514 82.252 1.00 86.19 ? 8 THR B N 1 ATOM 4236 C CA . THR B 1 8 ? -52.683 -15.931 81.579 1.00 86.41 ? 8 THR B CA 1 ATOM 4237 C C . THR B 1 8 ? -53.859 -15.956 82.547 1.00 86.89 ? 8 THR B C 1 ATOM 4238 O O . THR B 1 8 ? -53.672 -16.144 83.743 1.00 87.15 ? 8 THR B O 1 ATOM 4239 C CB . THR B 1 8 ? -52.553 -17.321 80.897 1.00 86.29 ? 8 THR B CB 1 ATOM 4240 O OG1 . THR B 1 8 ? -53.164 -18.339 81.702 1.00 85.52 ? 8 THR B OG1 1 ATOM 4241 C CG2 . THR B 1 8 ? -51.090 -17.666 80.622 1.00 86.31 ? 8 THR B CG2 1 ATOM 4242 N N . LYS B 1 9 ? -55.063 -15.751 82.028 1.00 87.39 ? 9 LYS B N 1 ATOM 4243 C CA . LYS B 1 9 ? -56.265 -15.807 82.848 1.00 87.91 ? 9 LYS B CA 1 ATOM 4244 C C . LYS B 1 9 ? -56.400 -17.184 83.488 1.00 88.02 ? 9 LYS B C 1 ATOM 4245 O O . LYS B 1 9 ? -57.398 -17.480 84.132 1.00 88.18 ? 9 LYS B O 1 ATOM 4246 C CB . LYS B 1 9 ? -57.525 -15.466 82.026 1.00 88.16 ? 9 LYS B CB 1 ATOM 4247 C CG . LYS B 1 9 ? -57.544 -14.060 81.336 1.00 89.29 ? 9 LYS B CG 1 ATOM 4248 C CD . LYS B 1 9 ? -57.417 -12.851 82.309 1.00 91.32 ? 9 LYS B CD 1 ATOM 4249 C CE . LYS B 1 9 ? -58.657 -12.657 83.226 1.00 92.07 ? 9 LYS B CE 1 ATOM 4250 N NZ . LYS B 1 9 ? -59.967 -12.554 82.489 1.00 92.63 ? 9 LYS B NZ 1 ATOM 4251 N N . ASN B 1 10 ? -55.390 -18.028 83.312 1.00 88.43 ? 10 ASN B N 1 ATOM 4252 C CA . ASN B 1 10 ? -55.374 -19.344 83.968 1.00 88.90 ? 10 ASN B CA 1 ATOM 4253 C C . ASN B 1 10 ? -54.224 -19.561 84.952 1.00 88.92 ? 10 ASN B C 1 ATOM 4254 O O . ASN B 1 10 ? -54.324 -20.381 85.873 1.00 89.22 ? 10 ASN B O 1 ATOM 4255 C CB . ASN B 1 10 ? -55.358 -20.478 82.939 1.00 88.97 ? 10 ASN B CB 1 ATOM 4256 C CG . ASN B 1 10 ? -56.697 -21.175 82.818 1.00 89.89 ? 10 ASN B CG 1 ATOM 4257 O OD1 . ASN B 1 10 ? -57.101 -21.562 81.723 1.00 91.65 ? 10 ASN B OD1 1 ATOM 4258 N ND2 . ASN B 1 10 ? -57.396 -21.341 83.946 1.00 89.88 ? 10 ASN B ND2 1 ATOM 4259 N N . GLY B 1 11 ? -53.133 -18.837 84.738 1.00 88.63 ? 11 GLY B N 1 ATOM 4260 C CA . GLY B 1 11 ? -51.942 -18.991 85.546 1.00 88.41 ? 11 GLY B CA 1 ATOM 4261 C C . GLY B 1 11 ? -50.746 -18.419 84.818 1.00 88.27 ? 11 GLY B C 1 ATOM 4262 O O . GLY B 1 11 ? -50.877 -17.843 83.734 1.00 88.45 ? 11 GLY B O 1 ATOM 4263 N N . LYS B 1 12 ? -49.569 -18.554 85.409 1.00 87.84 ? 12 LYS B N 1 ATOM 4264 C CA . LYS B 1 12 ? -48.397 -17.998 84.769 1.00 87.42 ? 12 LYS B CA 1 ATOM 4265 C C . LYS B 1 12 ? -47.732 -19.065 83.940 1.00 86.97 ? 12 LYS B C 1 ATOM 4266 O O . LYS B 1 12 ? -47.914 -20.260 84.179 1.00 86.81 ? 12 LYS B O 1 ATOM 4267 C CB . LYS B 1 12 ? -47.414 -17.406 85.778 1.00 87.61 ? 12 LYS B CB 1 ATOM 4268 C CG . LYS B 1 12 ? -47.958 -16.222 86.568 1.00 88.10 ? 12 LYS B CG 1 ATOM 4269 C CD . LYS B 1 12 ? -48.367 -16.641 87.984 1.00 89.60 ? 12 LYS B CD 1 ATOM 4270 C CE . LYS B 1 12 ? -48.590 -15.426 88.891 1.00 90.42 ? 12 LYS B CE 1 ATOM 4271 N NZ . LYS B 1 12 ? -47.474 -14.438 88.821 1.00 89.83 ? 12 LYS B NZ 1 ATOM 4272 N N . VAL B 1 13 ? -46.977 -18.622 82.945 1.00 86.46 ? 13 VAL B N 1 ATOM 4273 C CA . VAL B 1 13 ? -46.276 -19.540 82.073 1.00 85.91 ? 13 VAL B CA 1 ATOM 4274 C C . VAL B 1 13 ? -44.956 -18.938 81.653 1.00 85.71 ? 13 VAL B C 1 ATOM 4275 O O . VAL B 1 13 ? -44.877 -17.794 81.201 1.00 85.31 ? 13 VAL B O 1 ATOM 4276 C CB . VAL B 1 13 ? -47.098 -19.905 80.825 1.00 85.83 ? 13 VAL B CB 1 ATOM 4277 C CG1 . VAL B 1 13 ? -48.402 -20.562 81.225 1.00 85.60 ? 13 VAL B CG1 1 ATOM 4278 C CG2 . VAL B 1 13 ? -47.363 -18.673 79.988 1.00 85.75 ? 13 VAL B CG2 1 ATOM 4279 N N . ARG B 1 14 ? -43.909 -19.725 81.823 1.00 85.71 ? 14 ARG B N 1 ATOM 4280 C CA . ARG B 1 14 ? -42.575 -19.303 81.451 1.00 85.85 ? 14 ARG B CA 1 ATOM 4281 C C . ARG B 1 14 ? -42.330 -19.697 80.004 1.00 85.43 ? 14 ARG B C 1 ATOM 4282 O O . ARG B 1 14 ? -42.631 -20.835 79.610 1.00 85.39 ? 14 ARG B O 1 ATOM 4283 C CB . ARG B 1 14 ? -41.527 -19.953 82.378 1.00 86.25 ? 14 ARG B CB 1 ATOM 4284 C CG . ARG B 1 14 ? -40.051 -19.764 81.949 1.00 87.65 ? 14 ARG B CG 1 ATOM 4285 C CD . ARG B 1 14 ? -39.063 -20.134 83.064 1.00 90.56 ? 14 ARG B CD 1 ATOM 4286 N NE . ARG B 1 14 ? -39.346 -19.385 84.292 1.00 93.57 ? 14 ARG B NE 1 ATOM 4287 C CZ . ARG B 1 14 ? -40.033 -19.868 85.332 1.00 94.78 ? 14 ARG B CZ 1 ATOM 4288 N NH1 . ARG B 1 14 ? -40.499 -21.114 85.304 1.00 95.40 ? 14 ARG B NH1 1 ATOM 4289 N NH2 . ARG B 1 14 ? -40.252 -19.111 86.408 1.00 94.31 ? 14 ARG B NH2 1 ATOM 4290 N N . GLY B 1 15 ? -41.805 -18.742 79.227 1.00 84.98 ? 15 GLY B N 1 ATOM 4291 C CA . GLY B 1 15 ? -41.453 -18.951 77.821 1.00 84.39 ? 15 GLY B CA 1 ATOM 4292 C C . GLY B 1 15 ? -40.035 -19.455 77.681 1.00 83.91 ? 15 GLY B C 1 ATOM 4293 O O . GLY B 1 15 ? -39.487 -20.000 78.620 1.00 83.92 ? 15 GLY B O 1 ATOM 4294 N N . MET B 1 16 ? -39.442 -19.292 76.509 1.00 83.61 ? 16 MET B N 1 ATOM 4295 C CA . MET B 1 16 ? -38.042 -19.614 76.334 1.00 83.76 ? 16 MET B CA 1 ATOM 4296 C C . MET B 1 16 ? -37.551 -18.893 75.104 1.00 83.97 ? 16 MET B C 1 ATOM 4297 O O . MET B 1 16 ? -38.161 -18.997 74.052 1.00 84.23 ? 16 MET B O 1 ATOM 4298 C CB . MET B 1 16 ? -37.817 -21.121 76.214 1.00 83.61 ? 16 MET B CB 1 ATOM 4299 C CG . MET B 1 16 ? -38.190 -21.732 74.883 1.00 84.26 ? 16 MET B CG 1 ATOM 4300 S SD . MET B 1 16 ? -38.244 -23.549 74.946 1.00 86.30 ? 16 MET B SD 1 ATOM 4301 C CE . MET B 1 16 ? -36.505 -23.985 74.731 1.00 85.59 ? 16 MET B CE 1 ATOM 4302 N N . GLN B 1 17 ? -36.464 -18.138 75.238 1.00 84.16 ? 17 GLN B N 1 ATOM 4303 C CA . GLN B 1 17 ? -35.919 -17.391 74.107 1.00 84.39 ? 17 GLN B CA 1 ATOM 4304 C C . GLN B 1 17 ? -35.325 -18.356 73.095 1.00 84.06 ? 17 GLN B C 1 ATOM 4305 O O . GLN B 1 17 ? -34.836 -19.421 73.459 1.00 84.50 ? 17 GLN B O 1 ATOM 4306 C CB . GLN B 1 17 ? -34.842 -16.414 74.571 1.00 84.67 ? 17 GLN B CB 1 ATOM 4307 C CG . GLN B 1 17 ? -35.303 -15.482 75.687 1.00 87.47 ? 17 GLN B CG 1 ATOM 4308 C CD . GLN B 1 17 ? -36.517 -14.618 75.293 1.00 91.04 ? 17 GLN B CD 1 ATOM 4309 O OE1 . GLN B 1 17 ? -36.400 -13.393 75.172 1.00 92.71 ? 17 GLN B OE1 1 ATOM 4310 N NE2 . GLN B 1 17 ? -37.683 -15.253 75.093 1.00 92.00 ? 17 GLN B NE2 1 ATOM 4311 N N . LEU B 1 18 ? -35.378 -17.999 71.820 1.00 83.67 ? 18 LEU B N 1 ATOM 4312 C CA . LEU B 1 18 ? -34.732 -18.802 70.797 1.00 83.21 ? 18 LEU B CA 1 ATOM 4313 C C . LEU B 1 18 ? -34.091 -17.836 69.827 1.00 83.12 ? 18 LEU B C 1 ATOM 4314 O O . LEU B 1 18 ? -34.568 -16.711 69.628 1.00 82.94 ? 18 LEU B O 1 ATOM 4315 C CB . LEU B 1 18 ? -35.743 -19.719 70.082 1.00 83.19 ? 18 LEU B CB 1 ATOM 4316 C CG . LEU B 1 18 ? -36.795 -20.482 70.930 1.00 83.11 ? 18 LEU B CG 1 ATOM 4317 C CD1 . LEU B 1 18 ? -38.001 -20.906 70.090 1.00 83.05 ? 18 LEU B CD1 1 ATOM 4318 C CD2 . LEU B 1 18 ? -36.229 -21.686 71.705 1.00 82.45 ? 18 LEU B CD2 1 ATOM 4319 N N . THR B 1 19 ? -32.987 -18.261 69.241 1.00 83.19 ? 19 THR B N 1 ATOM 4320 C CA . THR B 1 19 ? -32.325 -17.442 68.243 1.00 83.50 ? 19 THR B CA 1 ATOM 4321 C C . THR B 1 19 ? -32.947 -17.686 66.884 1.00 83.54 ? 19 THR B C 1 ATOM 4322 O O . THR B 1 19 ? -33.117 -18.830 66.466 1.00 83.83 ? 19 THR B O 1 ATOM 4323 C CB . THR B 1 19 ? -30.842 -17.795 68.125 1.00 83.48 ? 19 THR B CB 1 ATOM 4324 O OG1 . THR B 1 19 ? -30.172 -17.384 69.311 1.00 84.14 ? 19 THR B OG1 1 ATOM 4325 C CG2 . THR B 1 19 ? -30.214 -17.074 66.943 1.00 83.78 ? 19 THR B CG2 1 ATOM 4326 N N . VAL B 1 20 ? -33.270 -16.619 66.172 1.00 83.47 ? 20 VAL B N 1 ATOM 4327 C CA . VAL B 1 20 ? -33.796 -16.803 64.830 1.00 83.35 ? 20 VAL B CA 1 ATOM 4328 C C . VAL B 1 20 ? -33.275 -15.746 63.858 1.00 83.28 ? 20 VAL B C 1 ATOM 4329 O O . VAL B 1 20 ? -33.646 -14.568 63.934 1.00 83.03 ? 20 VAL B O 1 ATOM 4330 C CB . VAL B 1 20 ? -35.345 -16.847 64.827 1.00 83.28 ? 20 VAL B CB 1 ATOM 4331 C CG1 . VAL B 1 20 ? -35.834 -17.648 63.636 1.00 83.53 ? 20 VAL B CG1 1 ATOM 4332 C CG2 . VAL B 1 20 ? -35.860 -17.469 66.104 1.00 82.60 ? 20 VAL B CG2 1 ATOM 4333 N N . PHE B 1 21 ? -32.414 -16.170 62.939 1.00 83.37 ? 21 PHE B N 1 ATOM 4334 C CA . PHE B 1 21 ? -31.853 -15.234 61.956 1.00 83.78 ? 21 PHE B CA 1 ATOM 4335 C C . PHE B 1 21 ? -31.348 -13.981 62.653 1.00 83.56 ? 21 PHE B C 1 ATOM 4336 O O . PHE B 1 21 ? -31.776 -12.869 62.321 1.00 83.59 ? 21 PHE B O 1 ATOM 4337 C CB . PHE B 1 21 ? -32.911 -14.812 60.924 1.00 83.94 ? 21 PHE B CB 1 ATOM 4338 C CG . PHE B 1 21 ? -33.598 -15.970 60.249 1.00 84.84 ? 21 PHE B CG 1 ATOM 4339 C CD1 . PHE B 1 21 ? -34.964 -16.139 60.376 1.00 84.75 ? 21 PHE B CD1 1 ATOM 4340 C CD2 . PHE B 1 21 ? -32.868 -16.900 59.491 1.00 85.63 ? 21 PHE B CD2 1 ATOM 4341 C CE1 . PHE B 1 21 ? -35.595 -17.206 59.755 1.00 85.40 ? 21 PHE B CE1 1 ATOM 4342 C CE2 . PHE B 1 21 ? -33.500 -17.979 58.873 1.00 85.39 ? 21 PHE B CE2 1 ATOM 4343 C CZ . PHE B 1 21 ? -34.861 -18.130 59.004 1.00 85.18 ? 21 PHE B CZ 1 ATOM 4344 N N . GLY B 1 22 ? -30.453 -14.166 63.622 1.00 83.23 ? 22 GLY B N 1 ATOM 4345 C CA . GLY B 1 22 ? -29.972 -13.060 64.439 1.00 82.60 ? 22 GLY B CA 1 ATOM 4346 C C . GLY B 1 22 ? -31.110 -12.248 65.042 1.00 82.12 ? 22 GLY B C 1 ATOM 4347 O O . GLY B 1 22 ? -31.162 -11.034 64.880 1.00 82.36 ? 22 GLY B O 1 ATOM 4348 N N . GLY B 1 23 ? -32.029 -12.921 65.731 1.00 81.43 ? 23 GLY B N 1 ATOM 4349 C CA . GLY B 1 23 ? -33.116 -12.251 66.436 1.00 80.21 ? 23 GLY B CA 1 ATOM 4350 C C . GLY B 1 23 ? -33.668 -13.150 67.522 1.00 79.64 ? 23 GLY B C 1 ATOM 4351 O O . GLY B 1 23 ? -33.361 -14.347 67.597 1.00 79.46 ? 23 GLY B O 1 ATOM 4352 N N . THR B 1 24 ? -34.482 -12.586 68.391 1.00 79.04 ? 24 THR B N 1 ATOM 4353 C CA . THR B 1 24 ? -35.045 -13.405 69.444 1.00 78.71 ? 24 THR B CA 1 ATOM 4354 C C . THR B 1 24 ? -36.520 -13.608 69.155 1.00 78.40 ? 24 THR B C 1 ATOM 4355 O O . THR B 1 24 ? -37.191 -12.708 68.616 1.00 78.72 ? 24 THR B O 1 ATOM 4356 C CB . THR B 1 24 ? -34.864 -12.752 70.846 1.00 78.78 ? 24 THR B CB 1 ATOM 4357 O OG1 . THR B 1 24 ? -33.471 -12.535 71.091 1.00 78.57 ? 24 THR B OG1 1 ATOM 4358 C CG2 . THR B 1 24 ? -35.459 -13.634 71.963 1.00 78.36 ? 24 THR B CG2 1 ATOM 4359 N N . VAL B 1 25 ? -37.016 -14.791 69.495 1.00 77.33 ? 25 VAL B N 1 ATOM 4360 C CA . VAL B 1 25 ? -38.450 -15.029 69.504 1.00 76.36 ? 25 VAL B CA 1 ATOM 4361 C C . VAL B 1 25 ? -38.723 -15.809 70.765 1.00 75.79 ? 25 VAL B C 1 ATOM 4362 O O . VAL B 1 25 ? -37.966 -16.716 71.120 1.00 75.77 ? 25 VAL B O 1 ATOM 4363 C CB . VAL B 1 25 ? -38.943 -15.858 68.284 1.00 76.36 ? 25 VAL B CB 1 ATOM 4364 C CG1 . VAL B 1 25 ? -40.379 -16.354 68.512 1.00 76.25 ? 25 VAL B CG1 1 ATOM 4365 C CG2 . VAL B 1 25 ? -38.862 -15.054 67.011 1.00 75.69 ? 25 VAL B CG2 1 ATOM 4366 N N . THR B 1 26 ? -39.796 -15.450 71.451 1.00 74.90 ? 26 THR B N 1 ATOM 4367 C CA . THR B 1 26 ? -40.181 -16.164 72.649 1.00 74.06 ? 26 THR B CA 1 ATOM 4368 C C . THR B 1 26 ? -41.139 -17.292 72.287 1.00 73.69 ? 26 THR B C 1 ATOM 4369 O O . THR B 1 26 ? -42.144 -17.072 71.604 1.00 73.62 ? 26 THR B O 1 ATOM 4370 C CB . THR B 1 26 ? -40.852 -15.224 73.659 1.00 74.13 ? 26 THR B CB 1 ATOM 4371 O OG1 . THR B 1 26 ? -40.074 -14.022 73.790 1.00 73.59 ? 26 THR B OG1 1 ATOM 4372 C CG2 . THR B 1 26 ? -40.994 -15.920 75.014 1.00 73.59 ? 26 THR B CG2 1 ATOM 4373 N N . ALA B 1 27 ? -40.815 -18.498 72.745 1.00 73.20 ? 27 ALA B N 1 ATOM 4374 C CA . ALA B 1 27 ? -41.641 -19.676 72.504 1.00 72.62 ? 27 ALA B CA 1 ATOM 4375 C C . ALA B 1 27 ? -42.338 -20.152 73.777 1.00 72.32 ? 27 ALA B C 1 ATOM 4376 O O . ALA B 1 27 ? -41.697 -20.398 74.792 1.00 72.58 ? 27 ALA B O 1 ATOM 4377 C CB . ALA B 1 27 ? -40.794 -20.808 71.909 1.00 72.28 ? 27 ALA B CB 1 ATOM 4378 N N . PHE B 1 28 ? -43.650 -20.303 73.716 1.00 71.92 ? 28 PHE B N 1 ATOM 4379 C CA . PHE B 1 28 ? -44.377 -20.949 74.790 1.00 71.72 ? 28 PHE B CA 1 ATOM 4380 C C . PHE B 1 28 ? -44.944 -22.312 74.391 1.00 71.12 ? 28 PHE B C 1 ATOM 4381 O O . PHE B 1 28 ? -46.141 -22.425 74.115 1.00 70.96 ? 28 PHE B O 1 ATOM 4382 C CB . PHE B 1 28 ? -45.505 -20.040 75.244 1.00 72.16 ? 28 PHE B CB 1 ATOM 4383 C CG . PHE B 1 28 ? -45.028 -18.759 75.861 1.00 73.71 ? 28 PHE B CG 1 ATOM 4384 C CD1 . PHE B 1 28 ? -44.527 -17.735 75.054 1.00 75.25 ? 28 PHE B CD1 1 ATOM 4385 C CD2 . PHE B 1 28 ? -45.070 -18.577 77.252 1.00 73.56 ? 28 PHE B CD2 1 ATOM 4386 C CE1 . PHE B 1 28 ? -44.090 -16.534 75.624 1.00 76.13 ? 28 PHE B CE1 1 ATOM 4387 C CE2 . PHE B 1 28 ? -44.630 -17.387 77.832 1.00 74.67 ? 28 PHE B CE2 1 ATOM 4388 C CZ . PHE B 1 28 ? -44.139 -16.364 77.023 1.00 75.53 ? 28 PHE B CZ 1 ATOM 4389 N N . LEU B 1 29 ? -44.092 -23.340 74.393 1.00 70.43 ? 29 LEU B N 1 ATOM 4390 C CA . LEU B 1 29 ? -44.499 -24.700 74.015 1.00 69.89 ? 29 LEU B CA 1 ATOM 4391 C C . LEU B 1 29 ? -45.237 -25.480 75.110 1.00 69.99 ? 29 LEU B C 1 ATOM 4392 O O . LEU B 1 29 ? -44.837 -25.489 76.265 1.00 70.12 ? 29 LEU B O 1 ATOM 4393 C CB . LEU B 1 29 ? -43.290 -25.514 73.583 1.00 69.40 ? 29 LEU B CB 1 ATOM 4394 C CG . LEU B 1 29 ? -42.291 -24.820 72.664 1.00 69.19 ? 29 LEU B CG 1 ATOM 4395 C CD1 . LEU B 1 29 ? -41.354 -25.857 72.033 1.00 67.43 ? 29 LEU B CD1 1 ATOM 4396 C CD2 . LEU B 1 29 ? -43.002 -24.018 71.586 1.00 69.73 ? 29 LEU B CD2 1 ATOM 4397 N N . GLY B 1 30 ? -46.319 -26.144 74.736 1.00 70.16 ? 30 GLY B N 1 ATOM 4398 C CA . GLY B 1 30 ? -46.979 -27.071 75.641 1.00 70.29 ? 30 GLY B CA 1 ATOM 4399 C C . GLY B 1 30 ? -47.994 -26.511 76.625 1.00 70.50 ? 30 GLY B C 1 ATOM 4400 O O . GLY B 1 30 ? -48.311 -27.179 77.607 1.00 70.98 ? 30 GLY B O 1 ATOM 4401 N N . ILE B 1 31 ? -48.527 -25.315 76.387 1.00 70.32 ? 31 ILE B N 1 ATOM 4402 C CA . ILE B 1 31 ? -49.560 -24.794 77.290 1.00 70.15 ? 31 ILE B CA 1 ATOM 4403 C C . ILE B 1 31 ? -50.847 -25.616 77.245 1.00 70.82 ? 31 ILE B C 1 ATOM 4404 O O . ILE B 1 31 ? -51.475 -25.755 76.196 1.00 70.98 ? 31 ILE B O 1 ATOM 4405 C CB . ILE B 1 31 ? -49.949 -23.357 76.973 1.00 69.63 ? 31 ILE B CB 1 ATOM 4406 C CG1 . ILE B 1 31 ? -48.711 -22.463 76.905 1.00 68.88 ? 31 ILE B CG1 1 ATOM 4407 C CG2 . ILE B 1 31 ? -50.946 -22.858 78.005 1.00 69.09 ? 31 ILE B CG2 1 ATOM 4408 C CD1 . ILE B 1 31 ? -49.015 -21.037 76.497 1.00 67.14 ? 31 ILE B CD1 1 ATOM 4409 N N . PRO B 1 32 ? -51.264 -26.155 78.393 1.00 71.24 ? 32 PRO B N 1 ATOM 4410 C CA . PRO B 1 32 ? -52.542 -26.859 78.414 1.00 71.54 ? 32 PRO B CA 1 ATOM 4411 C C . PRO B 1 32 ? -53.676 -25.858 78.203 1.00 71.63 ? 32 PRO B C 1 ATOM 4412 O O . PRO B 1 32 ? -53.622 -24.744 78.741 1.00 71.43 ? 32 PRO B O 1 ATOM 4413 C CB . PRO B 1 32 ? -52.597 -27.433 79.839 1.00 71.56 ? 32 PRO B CB 1 ATOM 4414 C CG . PRO B 1 32 ? -51.840 -26.424 80.655 1.00 71.42 ? 32 PRO B CG 1 ATOM 4415 C CD . PRO B 1 32 ? -50.698 -25.984 79.741 1.00 71.24 ? 32 PRO B CD 1 ATOM 4416 N N . TYR B 1 33 ? -54.686 -26.244 77.424 1.00 72.04 ? 33 TYR B N 1 ATOM 4417 C CA . TYR B 1 33 ? -55.849 -25.357 77.181 1.00 72.33 ? 33 TYR B CA 1 ATOM 4418 C C . TYR B 1 33 ? -57.147 -26.017 77.601 1.00 72.77 ? 33 TYR B C 1 ATOM 4419 O O . TYR B 1 33 ? -58.215 -25.408 77.586 1.00 72.63 ? 33 TYR B O 1 ATOM 4420 C CB . TYR B 1 33 ? -55.930 -24.888 75.716 1.00 71.94 ? 33 TYR B CB 1 ATOM 4421 C CG . TYR B 1 33 ? -56.162 -25.994 74.699 1.00 70.84 ? 33 TYR B CG 1 ATOM 4422 C CD1 . TYR B 1 33 ? -55.086 -26.635 74.066 1.00 69.20 ? 33 TYR B CD1 1 ATOM 4423 C CD2 . TYR B 1 33 ? -57.461 -26.381 74.362 1.00 69.28 ? 33 TYR B CD2 1 ATOM 4424 C CE1 . TYR B 1 33 ? -55.313 -27.642 73.133 1.00 68.98 ? 33 TYR B CE1 1 ATOM 4425 C CE2 . TYR B 1 33 ? -57.699 -27.379 73.434 1.00 67.98 ? 33 TYR B CE2 1 ATOM 4426 C CZ . TYR B 1 33 ? -56.630 -28.009 72.821 1.00 68.59 ? 33 TYR B CZ 1 ATOM 4427 O OH . TYR B 1 33 ? -56.881 -29.012 71.899 1.00 69.03 ? 33 TYR B OH 1 ATOM 4428 N N . ALA B 1 34 ? -57.041 -27.282 77.966 1.00 73.76 ? 34 ALA B N 1 ATOM 4429 C CA . ALA B 1 34 ? -58.169 -27.969 78.564 1.00 74.88 ? 34 ALA B CA 1 ATOM 4430 C C . ALA B 1 34 ? -57.706 -29.084 79.519 1.00 75.71 ? 34 ALA B C 1 ATOM 4431 O O . ALA B 1 34 ? -56.499 -29.392 79.653 1.00 75.76 ? 34 ALA B O 1 ATOM 4432 C CB . ALA B 1 34 ? -59.136 -28.512 77.488 1.00 74.60 ? 34 ALA B CB 1 ATOM 4433 N N . GLN B 1 35 ? -58.701 -29.687 80.160 1.00 76.48 ? 35 GLN B N 1 ATOM 4434 C CA . GLN B 1 35 ? -58.518 -30.567 81.297 1.00 77.23 ? 35 GLN B CA 1 ATOM 4435 C C . GLN B 1 35 ? -58.450 -32.036 80.838 1.00 77.16 ? 35 GLN B C 1 ATOM 4436 O O . GLN B 1 35 ? -59.422 -32.579 80.299 1.00 77.35 ? 35 GLN B O 1 ATOM 4437 C CB . GLN B 1 35 ? -59.682 -30.296 82.238 1.00 77.22 ? 35 GLN B CB 1 ATOM 4438 C CG . GLN B 1 35 ? -59.814 -31.197 83.401 1.00 79.46 ? 35 GLN B CG 1 ATOM 4439 C CD . GLN B 1 35 ? -61.231 -31.153 83.927 1.00 82.49 ? 35 GLN B CD 1 ATOM 4440 O OE1 . GLN B 1 35 ? -61.823 -30.070 84.060 1.00 83.02 ? 35 GLN B OE1 1 ATOM 4441 N NE2 . GLN B 1 35 ? -61.802 -32.334 84.208 1.00 83.80 ? 35 GLN B NE2 1 ATOM 4442 N N . PRO B 1 36 ? -57.288 -32.685 81.043 1.00 77.16 ? 36 PRO B N 1 ATOM 4443 C CA . PRO B 1 36 ? -57.052 -33.937 80.320 1.00 77.23 ? 36 PRO B CA 1 ATOM 4444 C C . PRO B 1 36 ? -58.288 -34.830 80.244 1.00 77.29 ? 36 PRO B C 1 ATOM 4445 O O . PRO B 1 36 ? -58.873 -35.167 81.270 1.00 77.40 ? 36 PRO B O 1 ATOM 4446 C CB . PRO B 1 36 ? -55.912 -34.590 81.110 1.00 76.83 ? 36 PRO B CB 1 ATOM 4447 C CG . PRO B 1 36 ? -55.119 -33.419 81.590 1.00 76.80 ? 36 PRO B CG 1 ATOM 4448 C CD . PRO B 1 36 ? -56.165 -32.359 81.942 1.00 77.02 ? 36 PRO B CD 1 ATOM 4449 N N . PRO B 1 37 ? -58.670 -35.229 79.023 1.00 77.29 ? 37 PRO B N 1 ATOM 4450 C CA . PRO B 1 37 ? -59.909 -35.955 78.789 1.00 77.37 ? 37 PRO B CA 1 ATOM 4451 C C . PRO B 1 37 ? -59.743 -37.424 79.130 1.00 77.60 ? 37 PRO B C 1 ATOM 4452 O O . PRO B 1 37 ? -59.706 -38.264 78.235 1.00 77.59 ? 37 PRO B O 1 ATOM 4453 C CB . PRO B 1 37 ? -60.078 -35.824 77.289 1.00 77.44 ? 37 PRO B CB 1 ATOM 4454 C CG . PRO B 1 37 ? -58.645 -35.919 76.784 1.00 77.44 ? 37 PRO B CG 1 ATOM 4455 C CD . PRO B 1 37 ? -57.787 -35.249 77.843 1.00 77.12 ? 37 PRO B CD 1 ATOM 4456 N N . LEU B 1 38 ? -59.664 -37.737 80.418 1.00 78.07 ? 38 LEU B N 1 ATOM 4457 C CA . LEU B 1 38 ? -59.286 -39.092 80.862 1.00 78.09 ? 38 LEU B CA 1 ATOM 4458 C C . LEU B 1 38 ? -60.381 -39.957 81.518 1.00 78.24 ? 38 LEU B C 1 ATOM 4459 O O . LEU B 1 38 ? -61.256 -39.470 82.251 1.00 77.52 ? 38 LEU B O 1 ATOM 4460 C CB . LEU B 1 38 ? -58.067 -39.009 81.777 1.00 77.86 ? 38 LEU B CB 1 ATOM 4461 C CG . LEU B 1 38 ? -56.803 -38.469 81.110 1.00 77.93 ? 38 LEU B CG 1 ATOM 4462 C CD1 . LEU B 1 38 ? -55.785 -38.037 82.162 1.00 77.72 ? 38 LEU B CD1 1 ATOM 4463 C CD2 . LEU B 1 38 ? -56.226 -39.517 80.154 1.00 77.92 ? 38 LEU B CD2 1 ATOM 4464 N N . GLY B 1 39 ? -60.307 -41.253 81.239 1.00 78.92 ? 39 GLY B N 1 ATOM 4465 C CA . GLY B 1 39 ? -61.253 -42.216 81.773 1.00 80.26 ? 39 GLY B CA 1 ATOM 4466 C C . GLY B 1 39 ? -62.693 -41.776 81.592 1.00 81.24 ? 39 GLY B C 1 ATOM 4467 O O . GLY B 1 39 ? -63.311 -42.048 80.547 1.00 81.65 ? 39 GLY B O 1 ATOM 4468 N N . ARG B 1 40 ? -63.224 -41.096 82.611 1.00 81.80 ? 40 ARG B N 1 ATOM 4469 C CA . ARG B 1 40 ? -64.614 -40.611 82.610 1.00 82.55 ? 40 ARG B CA 1 ATOM 4470 C C . ARG B 1 40 ? -64.861 -39.514 81.547 1.00 81.71 ? 40 ARG B C 1 ATOM 4471 O O . ARG B 1 40 ? -66.001 -39.307 81.095 1.00 81.47 ? 40 ARG B O 1 ATOM 4472 C CB . ARG B 1 40 ? -64.990 -40.124 84.021 1.00 83.23 ? 40 ARG B CB 1 ATOM 4473 C CG . ARG B 1 40 ? -63.746 -39.740 84.888 1.00 86.89 ? 40 ARG B CG 1 ATOM 4474 C CD . ARG B 1 40 ? -64.095 -39.413 86.364 1.00 92.01 ? 40 ARG B CD 1 ATOM 4475 N NE . ARG B 1 40 ? -65.239 -38.508 86.445 1.00 96.40 ? 40 ARG B NE 1 ATOM 4476 C CZ . ARG B 1 40 ? -65.179 -37.205 86.176 1.00 98.73 ? 40 ARG B CZ 1 ATOM 4477 N NH1 . ARG B 1 40 ? -64.025 -36.644 85.822 1.00 99.78 ? 40 ARG B NH1 1 ATOM 4478 N NH2 . ARG B 1 40 ? -66.272 -36.461 86.259 1.00 99.77 ? 40 ARG B NH2 1 ATOM 4479 N N . LEU B 1 41 ? -63.784 -38.830 81.149 1.00 80.75 ? 41 LEU B N 1 ATOM 4480 C CA . LEU B 1 41 ? -63.865 -37.775 80.140 1.00 79.60 ? 41 LEU B CA 1 ATOM 4481 C C . LEU B 1 41 ? -63.550 -38.255 78.717 1.00 79.03 ? 41 LEU B C 1 ATOM 4482 O O . LEU B 1 41 ? -63.768 -37.523 77.750 1.00 79.14 ? 41 LEU B O 1 ATOM 4483 C CB . LEU B 1 41 ? -62.983 -36.582 80.522 1.00 79.33 ? 41 LEU B CB 1 ATOM 4484 C CG . LEU B 1 41 ? -63.467 -35.846 81.765 1.00 79.10 ? 41 LEU B CG 1 ATOM 4485 C CD1 . LEU B 1 41 ? -62.667 -34.573 82.003 1.00 78.86 ? 41 LEU B CD1 1 ATOM 4486 C CD2 . LEU B 1 41 ? -64.932 -35.532 81.609 1.00 79.19 ? 41 LEU B CD2 1 ATOM 4487 N N . ARG B 1 42 ? -63.060 -39.478 78.570 1.00 78.21 ? 42 ARG B N 1 ATOM 4488 C CA . ARG B 1 42 ? -62.827 -39.984 77.226 1.00 77.65 ? 42 ARG B CA 1 ATOM 4489 C C . ARG B 1 42 ? -64.095 -39.916 76.371 1.00 77.74 ? 42 ARG B C 1 ATOM 4490 O O . ARG B 1 42 ? -65.177 -40.351 76.807 1.00 77.73 ? 42 ARG B O 1 ATOM 4491 C CB . ARG B 1 42 ? -62.333 -41.413 77.264 1.00 77.26 ? 42 ARG B CB 1 ATOM 4492 C CG . ARG B 1 42 ? -62.015 -41.936 75.887 1.00 75.77 ? 42 ARG B CG 1 ATOM 4493 C CD . ARG B 1 42 ? -61.738 -43.428 75.940 1.00 74.00 ? 42 ARG B CD 1 ATOM 4494 N NE . ARG B 1 42 ? -60.362 -43.736 76.326 1.00 71.87 ? 42 ARG B NE 1 ATOM 4495 C CZ . ARG B 1 42 ? -59.940 -44.948 76.656 1.00 70.35 ? 42 ARG B CZ 1 ATOM 4496 N NH1 . ARG B 1 42 ? -60.793 -45.968 76.663 1.00 69.50 ? 42 ARG B NH1 1 ATOM 4497 N NH2 . ARG B 1 42 ? -58.669 -45.135 76.974 1.00 69.09 ? 42 ARG B NH2 1 ATOM 4498 N N . PHE B 1 43 ? -63.954 -39.381 75.154 1.00 77.55 ? 43 PHE B N 1 ATOM 4499 C CA . PHE B 1 43 ? -65.088 -39.233 74.214 1.00 77.35 ? 43 PHE B CA 1 ATOM 4500 C C . PHE B 1 43 ? -66.021 -38.081 74.528 1.00 77.58 ? 43 PHE B C 1 ATOM 4501 O O . PHE B 1 43 ? -67.122 -38.033 73.994 1.00 77.67 ? 43 PHE B O 1 ATOM 4502 C CB . PHE B 1 43 ? -65.950 -40.495 74.153 1.00 76.99 ? 43 PHE B CB 1 ATOM 4503 C CG . PHE B 1 43 ? -65.219 -41.697 73.678 1.00 76.61 ? 43 PHE B CG 1 ATOM 4504 C CD1 . PHE B 1 43 ? -64.466 -41.649 72.511 1.00 76.60 ? 43 PHE B CD1 1 ATOM 4505 C CD2 . PHE B 1 43 ? -65.279 -42.883 74.395 1.00 75.41 ? 43 PHE B CD2 1 ATOM 4506 C CE1 . PHE B 1 43 ? -63.781 -42.769 72.074 1.00 76.20 ? 43 PHE B CE1 1 ATOM 4507 C CE2 . PHE B 1 43 ? -64.602 -44.009 73.964 1.00 74.61 ? 43 PHE B CE2 1 ATOM 4508 C CZ . PHE B 1 43 ? -63.851 -43.958 72.807 1.00 74.79 ? 43 PHE B CZ 1 ATOM 4509 N N . LYS B 1 44 ? -65.622 -37.172 75.408 1.00 78.02 ? 44 LYS B N 1 ATOM 4510 C CA . LYS B 1 44 ? -66.480 -36.024 75.708 1.00 78.60 ? 44 LYS B CA 1 ATOM 4511 C C . LYS B 1 44 ? -65.944 -34.722 75.138 1.00 78.57 ? 44 LYS B C 1 ATOM 4512 O O . LYS B 1 44 ? -64.779 -34.617 74.769 1.00 78.34 ? 44 LYS B O 1 ATOM 4513 C CB . LYS B 1 44 ? -66.689 -35.869 77.216 1.00 78.79 ? 44 LYS B CB 1 ATOM 4514 C CG . LYS B 1 44 ? -67.702 -36.832 77.789 1.00 80.24 ? 44 LYS B CG 1 ATOM 4515 C CD . LYS B 1 44 ? -68.213 -36.328 79.124 1.00 82.83 ? 44 LYS B CD 1 ATOM 4516 C CE . LYS B 1 44 ? -69.324 -37.226 79.652 1.00 85.06 ? 44 LYS B CE 1 ATOM 4517 N NZ . LYS B 1 44 ? -69.718 -36.814 81.033 1.00 87.34 ? 44 LYS B NZ 1 ATOM 4518 N N . LYS B 1 45 ? -66.806 -33.722 75.072 1.00 78.89 ? 45 LYS B N 1 ATOM 4519 C CA . LYS B 1 45 ? -66.341 -32.403 74.705 1.00 79.38 ? 45 LYS B CA 1 ATOM 4520 C C . LYS B 1 45 ? -65.282 -31.955 75.716 1.00 80.12 ? 45 LYS B C 1 ATOM 4521 O O . LYS B 1 45 ? -65.395 -32.245 76.912 1.00 80.05 ? 45 LYS B O 1 ATOM 4522 C CB . LYS B 1 45 ? -67.510 -31.409 74.628 1.00 79.26 ? 45 LYS B CB 1 ATOM 4523 C CG . LYS B 1 45 ? -68.550 -31.732 73.531 1.00 77.75 ? 45 LYS B CG 1 ATOM 4524 C CD . LYS B 1 45 ? -69.065 -30.467 72.862 1.00 75.38 ? 45 LYS B CD 1 ATOM 4525 C CE . LYS B 1 45 ? -70.308 -29.905 73.526 1.00 75.34 ? 45 LYS B CE 1 ATOM 4526 N NZ . LYS B 1 45 ? -70.414 -28.424 73.333 1.00 74.34 ? 45 LYS B NZ 1 ATOM 4527 N N . PRO B 1 46 ? -64.231 -31.278 75.232 1.00 80.88 ? 46 PRO B N 1 ATOM 4528 C CA . PRO B 1 46 ? -63.154 -30.775 76.072 1.00 81.83 ? 46 PRO B CA 1 ATOM 4529 C C . PRO B 1 46 ? -63.693 -29.963 77.237 1.00 83.03 ? 46 PRO B C 1 ATOM 4530 O O . PRO B 1 46 ? -64.664 -29.237 77.082 1.00 82.86 ? 46 PRO B O 1 ATOM 4531 C CB . PRO B 1 46 ? -62.338 -29.884 75.122 1.00 81.63 ? 46 PRO B CB 1 ATOM 4532 C CG . PRO B 1 46 ? -63.097 -29.831 73.858 1.00 81.25 ? 46 PRO B CG 1 ATOM 4533 C CD . PRO B 1 46 ? -63.960 -31.043 73.813 1.00 80.85 ? 46 PRO B CD 1 ATOM 4534 N N . GLN B 1 47 ? -63.055 -30.094 78.394 1.00 84.92 ? 47 GLN B N 1 ATOM 4535 C CA . GLN B 1 47 ? -63.543 -29.487 79.626 1.00 86.84 ? 47 GLN B CA 1 ATOM 4536 C C . GLN B 1 47 ? -62.731 -28.280 80.042 1.00 88.25 ? 47 GLN B C 1 ATOM 4537 O O . GLN B 1 47 ? -61.513 -28.260 79.866 1.00 88.41 ? 47 GLN B O 1 ATOM 4538 C CB . GLN B 1 47 ? -63.491 -30.511 80.745 1.00 86.89 ? 47 GLN B CB 1 ATOM 4539 C CG . GLN B 1 47 ? -64.588 -31.529 80.666 1.00 88.22 ? 47 GLN B CG 1 ATOM 4540 C CD . GLN B 1 47 ? -65.938 -30.933 80.998 1.00 90.14 ? 47 GLN B CD 1 ATOM 4541 O OE1 . GLN B 1 47 ? -66.486 -30.118 80.236 1.00 90.24 ? 47 GLN B OE1 1 ATOM 4542 N NE2 . GLN B 1 47 ? -66.488 -31.335 82.155 1.00 91.37 ? 47 GLN B NE2 1 ATOM 4543 N N . SER B 1 48 ? -63.398 -27.289 80.628 1.00 89.84 ? 48 SER B N 1 ATOM 4544 C CA A SER B 1 48 ? -62.732 -26.052 81.034 0.50 91.03 ? 48 SER B CA 1 ATOM 4545 C CA B SER B 1 48 ? -62.729 -26.050 81.033 0.50 90.93 ? 48 SER B CA 1 ATOM 4546 C C . SER B 1 48 ? -61.538 -26.303 81.956 1.00 91.80 ? 48 SER B C 1 ATOM 4547 O O . SER B 1 48 ? -61.501 -27.282 82.715 1.00 91.92 ? 48 SER B O 1 ATOM 4548 C CB A SER B 1 48 ? -63.731 -25.096 81.697 0.50 91.01 ? 48 SER B CB 1 ATOM 4549 C CB B SER B 1 48 ? -63.718 -25.078 81.692 0.50 90.88 ? 48 SER B CB 1 ATOM 4550 O OG A SER B 1 48 ? -64.293 -25.675 82.864 0.50 91.52 ? 48 SER B OG 1 ATOM 4551 O OG B SER B 1 48 ? -64.423 -24.311 80.729 0.50 90.76 ? 48 SER B OG 1 ATOM 4552 N N . LEU B 1 49 ? -60.560 -25.412 81.885 1.00 93.25 ? 49 LEU B N 1 ATOM 4553 C CA . LEU B 1 49 ? -59.367 -25.532 82.703 1.00 95.03 ? 49 LEU B CA 1 ATOM 4554 C C . LEU B 1 49 ? -59.511 -24.797 84.048 1.00 96.11 ? 49 LEU B C 1 ATOM 4555 O O . LEU B 1 49 ? -59.578 -23.558 84.081 1.00 96.26 ? 49 LEU B O 1 ATOM 4556 C CB . LEU B 1 49 ? -58.180 -24.980 81.919 1.00 94.88 ? 49 LEU B CB 1 ATOM 4557 C CG . LEU B 1 49 ? -56.822 -25.581 82.246 1.00 95.42 ? 49 LEU B CG 1 ATOM 4558 C CD1 . LEU B 1 49 ? -56.884 -27.115 82.230 1.00 95.29 ? 49 LEU B CD1 1 ATOM 4559 C CD2 . LEU B 1 49 ? -55.792 -25.045 81.253 1.00 95.14 ? 49 LEU B CD2 1 ATOM 4560 N N . THR B 1 50 ? -59.578 -25.553 85.150 1.00 97.47 ? 50 THR B N 1 ATOM 4561 C CA . THR B 1 50 ? -59.567 -24.946 86.508 1.00 98.67 ? 50 THR B CA 1 ATOM 4562 C C . THR B 1 50 ? -58.212 -24.249 86.801 1.00 99.20 ? 50 THR B C 1 ATOM 4563 O O . THR B 1 50 ? -57.152 -24.891 86.835 1.00 99.27 ? 50 THR B O 1 ATOM 4564 C CB . THR B 1 50 ? -59.964 -25.956 87.680 1.00 98.79 ? 50 THR B CB 1 ATOM 4565 O OG1 . THR B 1 50 ? -59.209 -27.173 87.581 1.00 98.93 ? 50 THR B OG1 1 ATOM 4566 C CG2 . THR B 1 50 ? -61.483 -26.278 87.693 1.00 98.68 ? 50 THR B CG2 1 ATOM 4567 N N . LYS B 1 51 ? -58.252 -22.935 86.993 1.00 99.75 ? 51 LYS B N 1 ATOM 4568 C CA . LYS B 1 51 ? -57.029 -22.147 87.024 1.00 100.48 ? 51 LYS B CA 1 ATOM 4569 C C . LYS B 1 51 ? -55.981 -22.870 87.841 1.00 100.54 ? 51 LYS B C 1 ATOM 4570 O O . LYS B 1 51 ? -56.257 -23.275 88.967 1.00 100.82 ? 51 LYS B O 1 ATOM 4571 C CB . LYS B 1 51 ? -57.289 -20.757 87.621 1.00 100.76 ? 51 LYS B CB 1 ATOM 4572 C CG . LYS B 1 51 ? -58.751 -20.286 87.573 1.00 102.19 ? 51 LYS B CG 1 ATOM 4573 C CD . LYS B 1 51 ? -59.462 -20.450 88.933 1.00 103.53 ? 51 LYS B CD 1 ATOM 4574 C CE . LYS B 1 51 ? -60.840 -19.783 88.942 1.00 103.61 ? 51 LYS B CE 1 ATOM 4575 N NZ . LYS B 1 51 ? -61.897 -20.582 88.271 1.00 103.40 ? 51 LYS B NZ 1 ATOM 4576 N N . TRP B 1 52 ? -54.784 -23.052 87.296 1.00 100.63 ? 52 TRP B N 1 ATOM 4577 C CA . TRP B 1 52 ? -53.703 -23.604 88.116 1.00 100.87 ? 52 TRP B CA 1 ATOM 4578 C C . TRP B 1 52 ? -53.034 -22.519 88.970 1.00 101.21 ? 52 TRP B C 1 ATOM 4579 O O . TRP B 1 52 ? -53.017 -21.332 88.607 1.00 101.11 ? 52 TRP B O 1 ATOM 4580 C CB . TRP B 1 52 ? -52.649 -24.332 87.276 1.00 100.69 ? 52 TRP B CB 1 ATOM 4581 C CG . TRP B 1 52 ? -51.793 -23.411 86.457 1.00 100.43 ? 52 TRP B CG 1 ATOM 4582 C CD1 . TRP B 1 52 ? -50.684 -22.712 86.871 1.00 100.21 ? 52 TRP B CD1 1 ATOM 4583 C CD2 . TRP B 1 52 ? -51.980 -23.084 85.080 1.00 100.07 ? 52 TRP B CD2 1 ATOM 4584 N NE1 . TRP B 1 52 ? -50.172 -21.977 85.828 1.00 100.01 ? 52 TRP B NE1 1 ATOM 4585 C CE2 . TRP B 1 52 ? -50.951 -22.187 84.719 1.00 100.39 ? 52 TRP B CE2 1 ATOM 4586 C CE3 . TRP B 1 52 ? -52.917 -23.465 84.115 1.00 99.74 ? 52 TRP B CE3 1 ATOM 4587 C CZ2 . TRP B 1 52 ? -50.839 -21.666 83.431 1.00 100.69 ? 52 TRP B CZ2 1 ATOM 4588 C CZ3 . TRP B 1 52 ? -52.803 -22.956 82.839 1.00 99.97 ? 52 TRP B CZ3 1 ATOM 4589 C CH2 . TRP B 1 52 ? -51.772 -22.061 82.506 1.00 100.65 ? 52 TRP B CH2 1 ATOM 4590 N N . SER B 1 53 ? -52.502 -22.943 90.117 1.00 101.62 ? 53 SER B N 1 ATOM 4591 C CA . SER B 1 53 ? -51.727 -22.070 91.000 1.00 101.71 ? 53 SER B CA 1 ATOM 4592 C C . SER B 1 53 ? -50.235 -22.225 90.651 1.00 101.64 ? 53 SER B C 1 ATOM 4593 O O . SER B 1 53 ? -49.783 -23.338 90.338 1.00 101.83 ? 53 SER B O 1 ATOM 4594 C CB . SER B 1 53 ? -51.987 -22.442 92.463 1.00 101.57 ? 53 SER B CB 1 ATOM 4595 O OG . SER B 1 53 ? -51.676 -21.354 93.308 1.00 101.49 ? 53 SER B OG 1 ATOM 4596 N N . ASP B 1 54 ? -49.474 -21.130 90.662 1.00 101.08 ? 54 ASP B N 1 ATOM 4597 C CA . ASP B 1 54 ? -48.052 -21.255 90.380 1.00 100.42 ? 54 ASP B CA 1 ATOM 4598 C C . ASP B 1 54 ? -47.666 -20.904 88.938 1.00 99.29 ? 54 ASP B C 1 ATOM 4599 O O . ASP B 1 54 ? -48.449 -20.349 88.172 1.00 99.26 ? 54 ASP B O 1 ATOM 4600 C CB . ASP B 1 54 ? -47.629 -22.706 90.645 1.00 100.90 ? 54 ASP B CB 1 ATOM 4601 C CG . ASP B 1 54 ? -46.301 -22.818 91.387 1.00 102.65 ? 54 ASP B CG 1 ATOM 4602 O OD1 . ASP B 1 54 ? -45.333 -22.096 91.032 1.00 104.48 ? 54 ASP B OD1 1 ATOM 4603 O OD2 . ASP B 1 54 ? -46.224 -23.650 92.326 1.00 104.56 ? 54 ASP B OD2 1 ATOM 4604 N N . ILE B 1 55 ? -46.437 -21.255 88.587 1.00 97.92 ? 55 ILE B N 1 ATOM 4605 C CA . ILE B 1 55 ? -45.919 -21.037 87.255 1.00 96.60 ? 55 ILE B CA 1 ATOM 4606 C C . ILE B 1 55 ? -45.885 -22.345 86.495 1.00 95.87 ? 55 ILE B C 1 ATOM 4607 O O . ILE B 1 55 ? -45.401 -23.361 87.002 1.00 95.75 ? 55 ILE B O 1 ATOM 4608 C CB . ILE B 1 55 ? -44.495 -20.444 87.275 1.00 96.53 ? 55 ILE B CB 1 ATOM 4609 C CG1 . ILE B 1 55 ? -44.567 -18.923 87.415 1.00 96.61 ? 55 ILE B CG1 1 ATOM 4610 C CG2 . ILE B 1 55 ? -43.734 -20.812 86.003 1.00 96.16 ? 55 ILE B CG2 1 ATOM 4611 C CD1 . ILE B 1 55 ? -43.251 -18.214 87.111 1.00 96.94 ? 55 ILE B CD1 1 ATOM 4612 N N . TRP B 1 56 ? -46.423 -22.308 85.279 1.00 94.77 ? 56 TRP B N 1 ATOM 4613 C CA . TRP B 1 56 ? -46.259 -23.399 84.334 1.00 93.38 ? 56 TRP B CA 1 ATOM 4614 C C . TRP B 1 56 ? -45.020 -23.161 83.465 1.00 93.13 ? 56 TRP B C 1 ATOM 4615 O O . TRP B 1 56 ? -44.938 -22.153 82.750 1.00 93.06 ? 56 TRP B O 1 ATOM 4616 C CB . TRP B 1 56 ? -47.497 -23.529 83.440 1.00 92.94 ? 56 TRP B CB 1 ATOM 4617 C CG . TRP B 1 56 ? -47.354 -24.660 82.482 1.00 90.42 ? 56 TRP B CG 1 ATOM 4618 C CD1 . TRP B 1 56 ? -46.580 -24.693 81.359 1.00 89.12 ? 56 TRP B CD1 1 ATOM 4619 C CD2 . TRP B 1 56 ? -47.978 -25.935 82.576 1.00 87.92 ? 56 TRP B CD2 1 ATOM 4620 N NE1 . TRP B 1 56 ? -46.687 -25.913 80.744 1.00 87.94 ? 56 TRP B NE1 1 ATOM 4621 C CE2 . TRP B 1 56 ? -47.540 -26.698 81.473 1.00 87.41 ? 56 TRP B CE2 1 ATOM 4622 C CE3 . TRP B 1 56 ? -48.874 -26.508 83.484 1.00 87.16 ? 56 TRP B CE3 1 ATOM 4623 C CZ2 . TRP B 1 56 ? -47.962 -28.007 81.256 1.00 86.70 ? 56 TRP B CZ2 1 ATOM 4624 C CZ3 . TRP B 1 56 ? -49.293 -27.809 83.272 1.00 86.61 ? 56 TRP B CZ3 1 ATOM 4625 C CH2 . TRP B 1 56 ? -48.835 -28.546 82.164 1.00 86.57 ? 56 TRP B CH2 1 ATOM 4626 N N . ASN B 1 57 ? -44.059 -24.082 83.532 1.00 92.56 ? 57 ASN B N 1 ATOM 4627 C CA . ASN B 1 57 ? -42.897 -24.035 82.632 1.00 92.17 ? 57 ASN B CA 1 ATOM 4628 C C . ASN B 1 57 ? -43.318 -24.531 81.243 1.00 90.82 ? 57 ASN B C 1 ATOM 4629 O O . ASN B 1 57 ? -43.544 -25.722 81.041 1.00 90.91 ? 57 ASN B O 1 ATOM 4630 C CB . ASN B 1 57 ? -41.722 -24.884 83.167 1.00 92.82 ? 57 ASN B CB 1 ATOM 4631 C CG . ASN B 1 57 ? -41.185 -24.388 84.521 1.00 95.54 ? 57 ASN B CG 1 ATOM 4632 O OD1 . ASN B 1 57 ? -41.813 -23.540 85.174 1.00 96.60 ? 57 ASN B OD1 1 ATOM 4633 N ND2 . ASN B 1 57 ? -40.022 -24.943 84.956 1.00 99.84 ? 57 ASN B ND2 1 ATOM 4634 N N . ALA B 1 58 ? -43.457 -23.628 80.285 1.00 89.06 ? 58 ALA B N 1 ATOM 4635 C CA . ALA B 1 58 ? -43.905 -24.048 78.970 1.00 87.36 ? 58 ALA B CA 1 ATOM 4636 C C . ALA B 1 58 ? -42.726 -24.076 78.005 1.00 86.43 ? 58 ALA B C 1 ATOM 4637 O O . ALA B 1 58 ? -42.619 -23.203 77.129 1.00 86.22 ? 58 ALA B O 1 ATOM 4638 C CB . ALA B 1 58 ? -44.967 -23.113 78.469 1.00 87.35 ? 58 ALA B CB 1 ATOM 4639 N N . THR B 1 59 ? -41.846 -25.073 78.149 1.00 84.93 ? 59 THR B N 1 ATOM 4640 C CA . THR B 1 59 ? -40.578 -25.059 77.403 1.00 83.66 ? 59 THR B CA 1 ATOM 4641 C C . THR B 1 59 ? -40.236 -26.323 76.634 1.00 82.67 ? 59 THR B C 1 ATOM 4642 O O . THR B 1 59 ? -39.116 -26.462 76.132 1.00 82.62 ? 59 THR B O 1 ATOM 4643 C CB . THR B 1 59 ? -39.398 -24.729 78.312 1.00 83.63 ? 59 THR B CB 1 ATOM 4644 O OG1 . THR B 1 59 ? -39.639 -25.292 79.604 1.00 84.73 ? 59 THR B OG1 1 ATOM 4645 C CG2 . THR B 1 59 ? -39.249 -23.233 78.454 1.00 83.42 ? 59 THR B CG2 1 ATOM 4646 N N . LYS B 1 60 ? -41.186 -27.248 76.543 1.00 81.48 ? 60 LYS B N 1 ATOM 4647 C CA . LYS B 1 60 ? -41.052 -28.378 75.619 1.00 80.06 ? 60 LYS B CA 1 ATOM 4648 C C . LYS B 1 60 ? -42.412 -28.665 74.985 1.00 78.92 ? 60 LYS B C 1 ATOM 4649 O O . LYS B 1 60 ? -43.454 -28.439 75.615 1.00 78.83 ? 60 LYS B O 1 ATOM 4650 C CB . LYS B 1 60 ? -40.514 -29.616 76.343 1.00 80.30 ? 60 LYS B CB 1 ATOM 4651 C CG . LYS B 1 60 ? -41.238 -29.961 77.653 1.00 80.79 ? 60 LYS B CG 1 ATOM 4652 C CD . LYS B 1 60 ? -41.007 -31.428 78.000 1.00 81.80 ? 60 LYS B CD 1 ATOM 4653 C CE . LYS B 1 60 ? -39.557 -31.824 77.687 1.00 83.10 ? 60 LYS B CE 1 ATOM 4654 N NZ . LYS B 1 60 ? -39.384 -33.267 77.336 1.00 83.61 ? 60 LYS B NZ 1 ATOM 4655 N N . TYR B 1 61 ? -42.408 -29.127 73.736 1.00 77.41 ? 61 TYR B N 1 ATOM 4656 C CA . TYR B 1 61 ? -43.643 -29.543 73.093 1.00 75.85 ? 61 TYR B CA 1 ATOM 4657 C C . TYR B 1 61 ? -44.318 -30.555 74.002 1.00 75.47 ? 61 TYR B C 1 ATOM 4658 O O . TYR B 1 61 ? -43.641 -31.304 74.706 1.00 75.55 ? 61 TYR B O 1 ATOM 4659 C CB . TYR B 1 61 ? -43.339 -30.205 71.769 1.00 75.37 ? 61 TYR B CB 1 ATOM 4660 C CG . TYR B 1 61 ? -43.002 -29.252 70.657 1.00 74.18 ? 61 TYR B CG 1 ATOM 4661 C CD1 . TYR B 1 61 ? -43.890 -28.258 70.277 1.00 73.76 ? 61 TYR B CD1 1 ATOM 4662 C CD2 . TYR B 1 61 ? -41.806 -29.366 69.958 1.00 72.71 ? 61 TYR B CD2 1 ATOM 4663 C CE1 . TYR B 1 61 ? -43.585 -27.393 69.234 1.00 72.29 ? 61 TYR B CE1 1 ATOM 4664 C CE2 . TYR B 1 61 ? -41.495 -28.515 68.919 1.00 70.75 ? 61 TYR B CE2 1 ATOM 4665 C CZ . TYR B 1 61 ? -42.384 -27.534 68.559 1.00 70.70 ? 61 TYR B CZ 1 ATOM 4666 O OH . TYR B 1 61 ? -42.068 -26.688 67.521 1.00 69.86 ? 61 TYR B OH 1 ATOM 4667 N N . ALA B 1 62 ? -45.646 -30.581 74.014 1.00 74.88 ? 62 ALA B N 1 ATOM 4668 C CA . ALA B 1 62 ? -46.345 -31.548 74.866 1.00 74.22 ? 62 ALA B CA 1 ATOM 4669 C C . ALA B 1 62 ? -46.585 -32.879 74.145 1.00 73.99 ? 62 ALA B C 1 ATOM 4670 O O . ALA B 1 62 ? -46.172 -33.075 72.979 1.00 73.43 ? 62 ALA B O 1 ATOM 4671 C CB . ALA B 1 62 ? -47.671 -30.966 75.410 1.00 74.07 ? 62 ALA B CB 1 ATOM 4672 N N . ASN B 1 63 ? -47.250 -33.785 74.864 1.00 73.79 ? 63 ASN B N 1 ATOM 4673 C CA . ASN B 1 63 ? -47.648 -35.073 74.324 1.00 73.70 ? 63 ASN B CA 1 ATOM 4674 C C . ASN B 1 63 ? -48.533 -34.916 73.094 1.00 73.38 ? 63 ASN B C 1 ATOM 4675 O O . ASN B 1 63 ? -49.569 -34.218 73.133 1.00 73.18 ? 63 ASN B O 1 ATOM 4676 C CB . ASN B 1 63 ? -48.467 -35.862 75.362 1.00 74.21 ? 63 ASN B CB 1 ATOM 4677 C CG . ASN B 1 63 ? -47.629 -36.388 76.519 1.00 75.24 ? 63 ASN B CG 1 ATOM 4678 O OD1 . ASN B 1 63 ? -46.494 -36.835 76.326 1.00 77.02 ? 63 ASN B OD1 1 ATOM 4679 N ND2 . ASN B 1 63 ? -48.193 -36.341 77.733 1.00 75.50 ? 63 ASN B ND2 1 ATOM 4680 N N . SER B 1 64 ? -48.143 -35.593 72.016 1.00 72.77 ? 64 SER B N 1 ATOM 4681 C CA . SER B 1 64 ? -49.050 -35.832 70.897 1.00 72.25 ? 64 SER B CA 1 ATOM 4682 C C . SER B 1 64 ? -50.238 -36.704 71.346 1.00 71.98 ? 64 SER B C 1 ATOM 4683 O O . SER B 1 64 ? -50.205 -37.302 72.415 1.00 72.03 ? 64 SER B O 1 ATOM 4684 C CB . SER B 1 64 ? -48.286 -36.494 69.760 1.00 72.24 ? 64 SER B CB 1 ATOM 4685 O OG . SER B 1 64 ? -47.188 -35.677 69.354 1.00 72.69 ? 64 SER B OG 1 ATOM 4686 N N . CYS B 1 65 ? -51.306 -36.750 70.559 1.00 71.85 ? 65 CYS B N 1 ATOM 4687 C CA . CYS B 1 65 ? -52.476 -37.548 70.947 1.00 71.81 ? 65 CYS B CA 1 ATOM 4688 C C . CYS B 1 65 ? -52.388 -38.933 70.348 1.00 71.94 ? 65 CYS B C 1 ATOM 4689 O O . CYS B 1 65 ? -51.678 -39.147 69.344 1.00 71.90 ? 65 CYS B O 1 ATOM 4690 C CB . CYS B 1 65 ? -53.776 -36.920 70.475 1.00 71.65 ? 65 CYS B CB 1 ATOM 4691 S SG . CYS B 1 65 ? -54.050 -35.294 71.110 1.00 72.39 ? 65 CYS B SG 1 ATOM 4692 N N . CYS B 1 66 ? -53.121 -39.869 70.948 1.00 71.66 ? 66 CYS B N 1 ATOM 4693 C CA . CYS B 1 66 ? -53.071 -41.249 70.492 1.00 71.96 ? 66 CYS B CA 1 ATOM 4694 C C . CYS B 1 66 ? -53.395 -41.321 69.019 1.00 71.38 ? 66 CYS B C 1 ATOM 4695 O O . CYS B 1 66 ? -54.165 -40.515 68.518 1.00 71.81 ? 66 CYS B O 1 ATOM 4696 C CB . CYS B 1 66 ? -54.024 -42.112 71.293 1.00 71.88 ? 66 CYS B CB 1 ATOM 4697 S SG . CYS B 1 66 ? -53.430 -42.242 72.955 1.00 75.52 ? 66 CYS B SG 1 ATOM 4698 N N . GLN B 1 67 ? -52.793 -42.280 68.329 1.00 70.73 ? 67 GLN B N 1 ATOM 4699 C CA . GLN B 1 67 ? -52.961 -42.400 66.908 1.00 70.08 ? 67 GLN B CA 1 ATOM 4700 C C . GLN B 1 67 ? -52.076 -43.516 66.430 1.00 70.12 ? 67 GLN B C 1 ATOM 4701 O O . GLN B 1 67 ? -51.127 -43.869 67.098 1.00 70.25 ? 67 GLN B O 1 ATOM 4702 C CB . GLN B 1 67 ? -52.555 -41.095 66.239 1.00 70.06 ? 67 GLN B CB 1 ATOM 4703 C CG . GLN B 1 67 ? -51.250 -40.490 66.741 1.00 68.78 ? 67 GLN B CG 1 ATOM 4704 C CD . GLN B 1 67 ? -50.659 -39.439 65.761 1.00 67.77 ? 67 GLN B CD 1 ATOM 4705 O OE1 . GLN B 1 67 ? -50.069 -39.792 64.717 1.00 66.33 ? 67 GLN B OE1 1 ATOM 4706 N NE2 . GLN B 1 67 ? -50.803 -38.150 66.107 1.00 65.17 ? 67 GLN B NE2 1 ATOM 4707 N N . ASN B 1 68 ? -52.382 -44.100 65.286 1.00 70.33 ? 68 ASN B N 1 ATOM 4708 C CA . ASN B 1 68 ? -51.444 -45.063 64.723 1.00 70.78 ? 68 ASN B CA 1 ATOM 4709 C C . ASN B 1 68 ? -50.291 -44.358 64.025 1.00 71.02 ? 68 ASN B C 1 ATOM 4710 O O . ASN B 1 68 ? -50.278 -43.127 63.916 1.00 70.97 ? 68 ASN B O 1 ATOM 4711 C CB . ASN B 1 68 ? -52.154 -46.072 63.827 1.00 70.75 ? 68 ASN B CB 1 ATOM 4712 C CG . ASN B 1 68 ? -53.270 -46.788 64.568 1.00 71.13 ? 68 ASN B CG 1 ATOM 4713 O OD1 . ASN B 1 68 ? -53.248 -46.887 65.803 1.00 71.00 ? 68 ASN B OD1 1 ATOM 4714 N ND2 . ASN B 1 68 ? -54.264 -47.266 63.830 1.00 72.14 ? 68 ASN B ND2 1 ATOM 4715 N N . ILE B 1 69 ? -49.309 -45.128 63.586 1.00 71.56 ? 69 ILE B N 1 ATOM 4716 C CA . ILE B 1 69 ? -48.108 -44.537 63.043 1.00 72.58 ? 69 ILE B CA 1 ATOM 4717 C C . ILE B 1 69 ? -47.807 -45.168 61.716 1.00 73.66 ? 69 ILE B C 1 ATOM 4718 O O . ILE B 1 69 ? -47.767 -46.392 61.586 1.00 74.04 ? 69 ILE B O 1 ATOM 4719 C CB . ILE B 1 69 ? -46.890 -44.742 63.967 1.00 72.46 ? 69 ILE B CB 1 ATOM 4720 C CG1 . ILE B 1 69 ? -46.796 -43.635 65.036 1.00 72.57 ? 69 ILE B CG1 1 ATOM 4721 C CG2 . ILE B 1 69 ? -45.617 -44.789 63.141 1.00 72.53 ? 69 ILE B CG2 1 ATOM 4722 C CD1 . ILE B 1 69 ? -47.491 -43.961 66.356 1.00 71.93 ? 69 ILE B CD1 1 ATOM 4723 N N . ASP B 1 70 ? -47.591 -44.331 60.721 1.00 75.09 ? 70 ASP B N 1 ATOM 4724 C CA . ASP B 1 70 ? -47.292 -44.833 59.393 1.00 76.85 ? 70 ASP B CA 1 ATOM 4725 C C . ASP B 1 70 ? -45.962 -45.607 59.417 1.00 77.81 ? 70 ASP B C 1 ATOM 4726 O O . ASP B 1 70 ? -44.903 -45.046 59.728 1.00 77.85 ? 70 ASP B O 1 ATOM 4727 C CB . ASP B 1 70 ? -47.260 -43.675 58.378 1.00 76.93 ? 70 ASP B CB 1 ATOM 4728 C CG . ASP B 1 70 ? -46.532 -44.041 57.084 1.00 77.76 ? 70 ASP B CG 1 ATOM 4729 O OD1 . ASP B 1 70 ? -46.218 -43.110 56.303 1.00 78.53 ? 70 ASP B OD1 1 ATOM 4730 O OD2 . ASP B 1 70 ? -46.260 -45.248 56.850 1.00 78.52 ? 70 ASP B OD2 1 ATOM 4731 N N . GLN B 1 71 ? -46.014 -46.899 59.107 1.00 78.98 ? 71 GLN B N 1 ATOM 4732 C CA . GLN B 1 71 ? -44.783 -47.665 59.104 1.00 80.35 ? 71 GLN B CA 1 ATOM 4733 C C . GLN B 1 71 ? -44.490 -48.412 57.813 1.00 80.68 ? 71 GLN B C 1 ATOM 4734 O O . GLN B 1 71 ? -43.721 -49.390 57.819 1.00 80.96 ? 71 GLN B O 1 ATOM 4735 C CB . GLN B 1 71 ? -44.746 -48.610 60.290 1.00 80.70 ? 71 GLN B CB 1 ATOM 4736 C CG . GLN B 1 71 ? -44.318 -47.920 61.560 1.00 83.29 ? 71 GLN B CG 1 ATOM 4737 C CD . GLN B 1 71 ? -44.834 -48.632 62.794 1.00 86.52 ? 71 GLN B CD 1 ATOM 4738 O OE1 . GLN B 1 71 ? -44.629 -48.176 63.921 1.00 88.35 ? 71 GLN B OE1 1 ATOM 4739 N NE2 . GLN B 1 71 ? -45.513 -49.761 62.587 1.00 87.39 ? 71 GLN B NE2 1 ATOM 4740 N N . SER B 1 72 ? -45.079 -47.943 56.712 1.00 80.93 ? 72 SER B N 1 ATOM 4741 C CA . SER B 1 72 ? -44.710 -48.435 55.378 1.00 81.20 ? 72 SER B CA 1 ATOM 4742 C C . SER B 1 72 ? -43.194 -48.361 55.133 1.00 81.37 ? 72 SER B C 1 ATOM 4743 O O . SER B 1 72 ? -42.607 -49.273 54.554 1.00 81.32 ? 72 SER B O 1 ATOM 4744 C CB . SER B 1 72 ? -45.431 -47.647 54.275 1.00 81.01 ? 72 SER B CB 1 ATOM 4745 O OG . SER B 1 72 ? -46.823 -47.899 54.250 1.00 81.43 ? 72 SER B OG 1 ATOM 4746 N N . PHE B 1 73 ? -42.551 -47.281 55.563 1.00 81.62 ? 73 PHE B N 1 ATOM 4747 C CA . PHE B 1 73 ? -41.170 -47.063 55.137 1.00 82.14 ? 73 PHE B CA 1 ATOM 4748 C C . PHE B 1 73 ? -40.247 -46.703 56.295 1.00 82.32 ? 73 PHE B C 1 ATOM 4749 O O . PHE B 1 73 ? -39.839 -45.526 56.439 1.00 82.29 ? 73 PHE B O 1 ATOM 4750 C CB . PHE B 1 73 ? -41.117 -45.990 54.028 1.00 82.31 ? 73 PHE B CB 1 ATOM 4751 C CG . PHE B 1 73 ? -42.127 -46.209 52.928 1.00 82.44 ? 73 PHE B CG 1 ATOM 4752 C CD1 . PHE B 1 73 ? -41.954 -47.232 51.994 1.00 82.06 ? 73 PHE B CD1 1 ATOM 4753 C CD2 . PHE B 1 73 ? -43.256 -45.405 52.834 1.00 82.75 ? 73 PHE B CD2 1 ATOM 4754 C CE1 . PHE B 1 73 ? -42.884 -47.445 50.986 1.00 81.87 ? 73 PHE B CE1 1 ATOM 4755 C CE2 . PHE B 1 73 ? -44.194 -45.613 51.817 1.00 82.78 ? 73 PHE B CE2 1 ATOM 4756 C CZ . PHE B 1 73 ? -44.005 -46.638 50.896 1.00 81.83 ? 73 PHE B CZ 1 ATOM 4757 N N . PRO B 1 74 ? -39.900 -47.718 57.120 1.00 82.42 ? 74 PRO B N 1 ATOM 4758 C CA . PRO B 1 74 ? -39.173 -47.435 58.373 1.00 82.03 ? 74 PRO B CA 1 ATOM 4759 C C . PRO B 1 74 ? -37.819 -46.850 58.004 1.00 81.41 ? 74 PRO B C 1 ATOM 4760 O O . PRO B 1 74 ? -37.175 -47.323 57.049 1.00 81.06 ? 74 PRO B O 1 ATOM 4761 C CB . PRO B 1 74 ? -39.036 -48.818 59.046 1.00 81.97 ? 74 PRO B CB 1 ATOM 4762 C CG . PRO B 1 74 ? -39.945 -49.752 58.256 1.00 82.36 ? 74 PRO B CG 1 ATOM 4763 C CD . PRO B 1 74 ? -39.975 -49.165 56.850 1.00 82.42 ? 74 PRO B CD 1 ATOM 4764 N N . GLY B 1 75 ? -37.420 -45.802 58.714 1.00 80.62 ? 75 GLY B N 1 ATOM 4765 C CA . GLY B 1 75 ? -36.193 -45.099 58.364 1.00 80.19 ? 75 GLY B CA 1 ATOM 4766 C C . GLY B 1 75 ? -36.307 -44.052 57.262 1.00 79.96 ? 75 GLY B C 1 ATOM 4767 O O . GLY B 1 75 ? -35.453 -43.167 57.159 1.00 79.74 ? 75 GLY B O 1 ATOM 4768 N N . PHE B 1 76 ? -37.350 -44.139 56.436 1.00 79.75 ? 76 PHE B N 1 ATOM 4769 C CA . PHE B 1 76 ? -37.541 -43.155 55.377 1.00 79.36 ? 76 PHE B CA 1 ATOM 4770 C C . PHE B 1 76 ? -37.996 -41.804 55.918 1.00 79.03 ? 76 PHE B C 1 ATOM 4771 O O . PHE B 1 76 ? -39.030 -41.713 56.596 1.00 79.04 ? 76 PHE B O 1 ATOM 4772 C CB . PHE B 1 76 ? -38.558 -43.643 54.359 1.00 79.52 ? 76 PHE B CB 1 ATOM 4773 C CG . PHE B 1 76 ? -38.693 -42.731 53.166 1.00 80.21 ? 76 PHE B CG 1 ATOM 4774 C CD1 . PHE B 1 76 ? -37.562 -42.184 52.564 1.00 79.78 ? 76 PHE B CD1 1 ATOM 4775 C CD2 . PHE B 1 76 ? -39.946 -42.426 52.641 1.00 80.49 ? 76 PHE B CD2 1 ATOM 4776 C CE1 . PHE B 1 76 ? -37.683 -41.354 51.465 1.00 80.19 ? 76 PHE B CE1 1 ATOM 4777 C CE2 . PHE B 1 76 ? -40.069 -41.596 51.535 1.00 80.19 ? 76 PHE B CE2 1 ATOM 4778 C CZ . PHE B 1 76 ? -38.936 -41.059 50.947 1.00 80.20 ? 76 PHE B CZ 1 ATOM 4779 N N . HIS B 1 77 ? -37.242 -40.746 55.610 1.00 78.45 ? 77 HIS B N 1 ATOM 4780 C CA . HIS B 1 77 ? -37.627 -39.414 56.090 1.00 77.91 ? 77 HIS B CA 1 ATOM 4781 C C . HIS B 1 77 ? -39.015 -39.079 55.530 1.00 77.28 ? 77 HIS B C 1 ATOM 4782 O O . HIS B 1 77 ? -39.932 -38.674 56.287 1.00 76.89 ? 77 HIS B O 1 ATOM 4783 C CB . HIS B 1 77 ? -36.586 -38.339 55.708 1.00 77.88 ? 77 HIS B CB 1 ATOM 4784 C CG . HIS B 1 77 ? -36.940 -36.960 56.190 1.00 78.88 ? 77 HIS B CG 1 ATOM 4785 N ND1 . HIS B 1 77 ? -37.337 -36.703 57.489 1.00 79.65 ? 77 HIS B ND1 1 ATOM 4786 C CD2 . HIS B 1 77 ? -36.971 -35.765 55.544 1.00 79.38 ? 77 HIS B CD2 1 ATOM 4787 C CE1 . HIS B 1 77 ? -37.590 -35.410 57.624 1.00 79.64 ? 77 HIS B CE1 1 ATOM 4788 N NE2 . HIS B 1 77 ? -37.380 -34.819 56.458 1.00 79.90 ? 77 HIS B NE2 1 ATOM 4789 N N . GLY B 1 78 ? -39.145 -39.294 54.208 1.00 76.43 ? 78 GLY B N 1 ATOM 4790 C CA . GLY B 1 78 ? -40.333 -38.946 53.419 1.00 75.24 ? 78 GLY B CA 1 ATOM 4791 C C . GLY B 1 78 ? -41.654 -39.244 54.093 1.00 74.49 ? 78 GLY B C 1 ATOM 4792 O O . GLY B 1 78 ? -42.555 -38.405 54.123 1.00 73.95 ? 78 GLY B O 1 ATOM 4793 N N . SER B 1 79 ? -41.772 -40.445 54.645 1.00 74.03 ? 79 SER B N 1 ATOM 4794 C CA . SER B 1 79 ? -43.001 -40.822 55.340 1.00 73.73 ? 79 SER B CA 1 ATOM 4795 C C . SER B 1 79 ? -42.931 -40.505 56.841 1.00 73.38 ? 79 SER B C 1 ATOM 4796 O O . SER B 1 79 ? -43.954 -40.180 57.472 1.00 73.04 ? 79 SER B O 1 ATOM 4797 C CB . SER B 1 79 ? -43.307 -42.307 55.139 1.00 73.71 ? 79 SER B CB 1 ATOM 4798 O OG . SER B 1 79 ? -42.593 -43.091 56.083 1.00 74.28 ? 79 SER B OG 1 ATOM 4799 N N . GLU B 1 80 ? -41.723 -40.586 57.407 1.00 73.20 ? 80 GLU B N 1 ATOM 4800 C CA . GLU B 1 80 ? -41.565 -40.494 58.866 1.00 73.05 ? 80 GLU B CA 1 ATOM 4801 C C . GLU B 1 80 ? -41.659 -39.087 59.407 1.00 72.30 ? 80 GLU B C 1 ATOM 4802 O O . GLU B 1 80 ? -42.172 -38.874 60.515 1.00 71.79 ? 80 GLU B O 1 ATOM 4803 C CB . GLU B 1 80 ? -40.297 -41.200 59.343 1.00 73.25 ? 80 GLU B CB 1 ATOM 4804 C CG . GLU B 1 80 ? -40.573 -42.677 59.698 1.00 75.92 ? 80 GLU B CG 1 ATOM 4805 C CD . GLU B 1 80 ? -39.313 -43.512 59.912 1.00 78.79 ? 80 GLU B CD 1 ATOM 4806 O OE1 . GLU B 1 80 ? -39.396 -44.532 60.635 1.00 79.74 ? 80 GLU B OE1 1 ATOM 4807 O OE2 . GLU B 1 80 ? -38.246 -43.145 59.359 1.00 80.29 ? 80 GLU B OE2 1 ATOM 4808 N N . MET B 1 81 ? -41.200 -38.127 58.599 1.00 71.59 ? 81 MET B N 1 ATOM 4809 C CA . MET B 1 81 ? -41.305 -36.710 58.949 1.00 70.59 ? 81 MET B CA 1 ATOM 4810 C C . MET B 1 81 ? -42.715 -36.308 59.398 1.00 70.23 ? 81 MET B C 1 ATOM 4811 O O . MET B 1 81 ? -42.898 -35.258 60.016 1.00 70.46 ? 81 MET B O 1 ATOM 4812 C CB . MET B 1 81 ? -40.891 -35.841 57.771 1.00 70.26 ? 81 MET B CB 1 ATOM 4813 C CG . MET B 1 81 ? -41.959 -35.689 56.746 1.00 69.21 ? 81 MET B CG 1 ATOM 4814 S SD . MET B 1 81 ? -41.344 -34.623 55.454 1.00 69.58 ? 81 MET B SD 1 ATOM 4815 C CE . MET B 1 81 ? -41.536 -32.994 56.174 1.00 68.99 ? 81 MET B CE 1 ATOM 4816 N N . TRP B 1 82 ? -43.715 -37.131 59.077 1.00 69.57 ? 82 TRP B N 1 ATOM 4817 C CA . TRP B 1 82 ? -45.087 -36.807 59.451 1.00 68.41 ? 82 TRP B CA 1 ATOM 4818 C C . TRP B 1 82 ? -45.475 -37.507 60.736 1.00 68.45 ? 82 TRP B C 1 ATOM 4819 O O . TRP B 1 82 ? -46.440 -37.099 61.355 1.00 68.96 ? 82 TRP B O 1 ATOM 4820 C CB . TRP B 1 82 ? -46.078 -37.118 58.320 1.00 67.62 ? 82 TRP B CB 1 ATOM 4821 C CG . TRP B 1 82 ? -45.686 -36.463 57.038 1.00 65.53 ? 82 TRP B CG 1 ATOM 4822 C CD1 . TRP B 1 82 ? -45.030 -37.042 55.982 1.00 65.00 ? 82 TRP B CD1 1 ATOM 4823 C CD2 . TRP B 1 82 ? -45.889 -35.090 56.677 1.00 63.85 ? 82 TRP B CD2 1 ATOM 4824 N NE1 . TRP B 1 82 ? -44.829 -36.116 54.971 1.00 64.09 ? 82 TRP B NE1 1 ATOM 4825 C CE2 . TRP B 1 82 ? -45.341 -34.913 55.371 1.00 63.42 ? 82 TRP B CE2 1 ATOM 4826 C CE3 . TRP B 1 82 ? -46.485 -34.000 57.319 1.00 62.12 ? 82 TRP B CE3 1 ATOM 4827 C CZ2 . TRP B 1 82 ? -45.368 -33.701 54.711 1.00 62.33 ? 82 TRP B CZ2 1 ATOM 4828 C CZ3 . TRP B 1 82 ? -46.521 -32.803 56.664 1.00 61.67 ? 82 TRP B CZ3 1 ATOM 4829 C CH2 . TRP B 1 82 ? -45.962 -32.656 55.366 1.00 62.65 ? 82 TRP B CH2 1 ATOM 4830 N N . ASN B 1 83 ? -44.738 -38.544 61.147 1.00 68.37 ? 83 ASN B N 1 ATOM 4831 C CA . ASN B 1 83 ? -45.058 -39.245 62.417 1.00 68.29 ? 83 ASN B CA 1 ATOM 4832 C C . ASN B 1 83 ? -44.896 -38.341 63.637 1.00 68.12 ? 83 ASN B C 1 ATOM 4833 O O . ASN B 1 83 ? -44.073 -37.433 63.634 1.00 68.22 ? 83 ASN B O 1 ATOM 4834 C CB . ASN B 1 83 ? -44.200 -40.505 62.601 1.00 68.39 ? 83 ASN B CB 1 ATOM 4835 C CG . ASN B 1 83 ? -44.639 -41.654 61.705 1.00 68.60 ? 83 ASN B CG 1 ATOM 4836 O OD1 . ASN B 1 83 ? -45.760 -42.175 61.843 1.00 68.82 ? 83 ASN B OD1 1 ATOM 4837 N ND2 . ASN B 1 83 ? -43.754 -42.064 60.783 1.00 68.03 ? 83 ASN B ND2 1 ATOM 4838 N N . PRO B 1 84 ? -45.670 -38.598 64.696 1.00 68.15 ? 84 PRO B N 1 ATOM 4839 C CA . PRO B 1 84 ? -45.578 -37.727 65.886 1.00 68.35 ? 84 PRO B CA 1 ATOM 4840 C C . PRO B 1 84 ? -44.167 -37.739 66.481 1.00 68.66 ? 84 PRO B C 1 ATOM 4841 O O . PRO B 1 84 ? -43.557 -38.809 66.581 1.00 68.79 ? 84 PRO B O 1 ATOM 4842 C CB . PRO B 1 84 ? -46.581 -38.343 66.888 1.00 67.83 ? 84 PRO B CB 1 ATOM 4843 C CG . PRO B 1 84 ? -46.999 -39.664 66.317 1.00 67.72 ? 84 PRO B CG 1 ATOM 4844 C CD . PRO B 1 84 ? -46.463 -39.821 64.918 1.00 68.22 ? 84 PRO B CD 1 ATOM 4845 N N . ASN B 1 85 ? -43.647 -36.578 66.879 1.00 68.92 ? 85 ASN B N 1 ATOM 4846 C CA . ASN B 1 85 ? -42.347 -36.555 67.573 1.00 69.21 ? 85 ASN B CA 1 ATOM 4847 C C . ASN B 1 85 ? -42.404 -36.284 69.099 1.00 69.80 ? 85 ASN B C 1 ATOM 4848 O O . ASN B 1 85 ? -41.463 -35.744 69.687 1.00 70.20 ? 85 ASN B O 1 ATOM 4849 C CB . ASN B 1 85 ? -41.351 -35.618 66.874 1.00 68.90 ? 85 ASN B CB 1 ATOM 4850 C CG . ASN B 1 85 ? -41.933 -34.241 66.597 1.00 68.72 ? 85 ASN B CG 1 ATOM 4851 O OD1 . ASN B 1 85 ? -42.960 -33.846 67.163 1.00 67.21 ? 85 ASN B OD1 1 ATOM 4852 N ND2 . ASN B 1 85 ? -41.269 -33.498 65.717 1.00 69.25 ? 85 ASN B ND2 1 ATOM 4853 N N . THR B 1 86 ? -43.496 -36.665 69.745 1.00 69.99 ? 86 THR B N 1 ATOM 4854 C CA . THR B 1 86 ? -43.517 -36.639 71.179 1.00 70.53 ? 86 THR B CA 1 ATOM 4855 C C . THR B 1 86 ? -44.333 -37.841 71.619 1.00 71.08 ? 86 THR B C 1 ATOM 4856 O O . THR B 1 86 ? -45.000 -38.465 70.796 1.00 71.10 ? 86 THR B O 1 ATOM 4857 C CB . THR B 1 86 ? -44.087 -35.309 71.706 1.00 70.58 ? 86 THR B CB 1 ATOM 4858 O OG1 . THR B 1 86 ? -45.522 -35.353 71.736 1.00 71.83 ? 86 THR B OG1 1 ATOM 4859 C CG2 . THR B 1 86 ? -43.650 -34.168 70.831 1.00 69.96 ? 86 THR B CG2 1 ATOM 4860 N N . ASP B 1 87 ? -44.260 -38.193 72.899 1.00 71.78 ? 87 ASP B N 1 ATOM 4861 C CA . ASP B 1 87 ? -45.060 -39.313 73.422 1.00 72.69 ? 87 ASP B CA 1 ATOM 4862 C C . ASP B 1 87 ? -46.568 -39.208 73.139 1.00 72.50 ? 87 ASP B C 1 ATOM 4863 O O . ASP B 1 87 ? -47.240 -38.239 73.536 1.00 72.71 ? 87 ASP B O 1 ATOM 4864 C CB . ASP B 1 87 ? -44.874 -39.462 74.942 1.00 73.45 ? 87 ASP B CB 1 ATOM 4865 C CG . ASP B 1 87 ? -43.569 -40.165 75.318 1.00 75.71 ? 87 ASP B CG 1 ATOM 4866 O OD1 . ASP B 1 87 ? -42.488 -39.639 74.948 1.00 78.59 ? 87 ASP B OD1 1 ATOM 4867 O OD2 . ASP B 1 87 ? -43.623 -41.235 75.991 1.00 76.94 ? 87 ASP B OD2 1 ATOM 4868 N N . LEU B 1 88 ? -47.100 -40.231 72.485 1.00 72.17 ? 88 LEU B N 1 ATOM 4869 C CA . LEU B 1 88 ? -48.544 -40.391 72.379 1.00 71.94 ? 88 LEU B CA 1 ATOM 4870 C C . LEU B 1 88 ? -49.137 -40.542 73.757 1.00 71.98 ? 88 LEU B C 1 ATOM 4871 O O . LEU B 1 88 ? -48.575 -41.234 74.612 1.00 72.21 ? 88 LEU B O 1 ATOM 4872 C CB . LEU B 1 88 ? -48.898 -41.658 71.602 1.00 71.97 ? 88 LEU B CB 1 ATOM 4873 C CG . LEU B 1 88 ? -48.201 -41.837 70.265 1.00 71.19 ? 88 LEU B CG 1 ATOM 4874 C CD1 . LEU B 1 88 ? -49.027 -42.814 69.480 1.00 70.71 ? 88 LEU B CD1 1 ATOM 4875 C CD2 . LEU B 1 88 ? -48.084 -40.485 69.572 1.00 70.60 ? 88 LEU B CD2 1 ATOM 4876 N N . SER B 1 89 ? -50.306 -39.947 73.949 1.00 72.24 ? 89 SER B N 1 ATOM 4877 C CA . SER B 1 89 ? -50.962 -39.947 75.240 1.00 72.42 ? 89 SER B CA 1 ATOM 4878 C C . SER B 1 89 ? -52.406 -39.558 75.045 1.00 72.56 ? 89 SER B C 1 ATOM 4879 O O . SER B 1 89 ? -52.730 -38.757 74.164 1.00 72.77 ? 89 SER B O 1 ATOM 4880 C CB . SER B 1 89 ? -50.279 -38.923 76.161 1.00 72.31 ? 89 SER B CB 1 ATOM 4881 O OG . SER B 1 89 ? -50.978 -38.790 77.383 1.00 72.43 ? 89 SER B OG 1 ATOM 4882 N N . GLU B 1 90 ? -53.277 -40.117 75.865 1.00 72.87 ? 90 GLU B N 1 ATOM 4883 C CA . GLU B 1 90 ? -54.618 -39.556 75.991 1.00 73.41 ? 90 GLU B CA 1 ATOM 4884 C C . GLU B 1 90 ? -54.553 -38.109 76.537 1.00 73.34 ? 90 GLU B C 1 ATOM 4885 O O . GLU B 1 90 ? -55.472 -37.304 76.352 1.00 73.68 ? 90 GLU B O 1 ATOM 4886 C CB . GLU B 1 90 ? -55.488 -40.423 76.903 1.00 73.41 ? 90 GLU B CB 1 ATOM 4887 C CG . GLU B 1 90 ? -56.003 -41.682 76.239 1.00 74.99 ? 90 GLU B CG 1 ATOM 4888 C CD . GLU B 1 90 ? -57.325 -42.172 76.835 1.00 77.69 ? 90 GLU B CD 1 ATOM 4889 O OE1 . GLU B 1 90 ? -57.296 -43.124 77.648 1.00 78.63 ? 90 GLU B OE1 1 ATOM 4890 O OE2 . GLU B 1 90 ? -58.398 -41.614 76.491 1.00 78.63 ? 90 GLU B OE2 1 ATOM 4891 N N . ASP B 1 91 ? -53.464 -37.778 77.216 1.00 73.02 ? 91 ASP B N 1 ATOM 4892 C CA . ASP B 1 91 ? -53.340 -36.452 77.786 1.00 72.64 ? 91 ASP B CA 1 ATOM 4893 C C . ASP B 1 91 ? -52.537 -35.571 76.838 1.00 72.36 ? 91 ASP B C 1 ATOM 4894 O O . ASP B 1 91 ? -51.294 -35.567 76.878 1.00 72.51 ? 91 ASP B O 1 ATOM 4895 C CB . ASP B 1 91 ? -52.663 -36.518 79.152 1.00 72.58 ? 91 ASP B CB 1 ATOM 4896 C CG . ASP B 1 91 ? -52.496 -35.157 79.767 1.00 72.28 ? 91 ASP B CG 1 ATOM 4897 O OD1 . ASP B 1 91 ? -52.235 -34.191 79.012 1.00 72.89 ? 91 ASP B OD1 1 ATOM 4898 O OD2 . ASP B 1 91 ? -52.632 -35.048 80.998 1.00 72.41 ? 91 ASP B OD2 1 ATOM 4899 N N . CYS B 1 92 ? -53.242 -34.814 75.998 1.00 71.63 ? 92 CYS B N 1 ATOM 4900 C CA . CYS B 1 92 ? -52.567 -34.126 74.908 1.00 71.03 ? 92 CYS B CA 1 ATOM 4901 C C . CYS B 1 92 ? -53.158 -32.757 74.506 1.00 70.33 ? 92 CYS B C 1 ATOM 4902 O O . CYS B 1 92 ? -52.744 -32.165 73.494 1.00 70.49 ? 92 CYS B O 1 ATOM 4903 C CB . CYS B 1 92 ? -52.510 -35.061 73.709 1.00 71.09 ? 92 CYS B CB 1 ATOM 4904 S SG . CYS B 1 92 ? -54.168 -35.502 73.145 1.00 72.22 ? 92 CYS B SG 1 ATOM 4905 N N . LEU B 1 93 ? -54.095 -32.240 75.294 1.00 69.23 ? 93 LEU B N 1 ATOM 4906 C CA . LEU B 1 93 ? -54.675 -30.947 74.969 1.00 68.31 ? 93 LEU B CA 1 ATOM 4907 C C . LEU B 1 93 ? -53.785 -29.779 75.393 1.00 68.19 ? 93 LEU B C 1 ATOM 4908 O O . LEU B 1 93 ? -54.057 -29.071 76.366 1.00 68.12 ? 93 LEU B O 1 ATOM 4909 C CB . LEU B 1 93 ? -56.084 -30.806 75.540 1.00 67.90 ? 93 LEU B CB 1 ATOM 4910 C CG . LEU B 1 93 ? -57.033 -31.951 75.191 1.00 67.36 ? 93 LEU B CG 1 ATOM 4911 C CD1 . LEU B 1 93 ? -58.450 -31.446 75.209 1.00 67.54 ? 93 LEU B CD1 1 ATOM 4912 C CD2 . LEU B 1 93 ? -56.723 -32.566 73.852 1.00 66.71 ? 93 LEU B CD2 1 ATOM 4913 N N . TYR B 1 94 ? -52.718 -29.569 74.641 1.00 68.07 ? 94 TYR B N 1 ATOM 4914 C CA . TYR B 1 94 ? -51.875 -28.408 74.860 1.00 68.36 ? 94 TYR B CA 1 ATOM 4915 C C . TYR B 1 94 ? -51.693 -27.680 73.538 1.00 68.30 ? 94 TYR B C 1 ATOM 4916 O O . TYR B 1 94 ? -52.044 -28.208 72.471 1.00 68.59 ? 94 TYR B O 1 ATOM 4917 C CB . TYR B 1 94 ? -50.522 -28.835 75.424 1.00 68.54 ? 94 TYR B CB 1 ATOM 4918 C CG . TYR B 1 94 ? -50.681 -29.752 76.611 1.00 69.95 ? 94 TYR B CG 1 ATOM 4919 C CD1 . TYR B 1 94 ? -50.946 -31.116 76.431 1.00 70.30 ? 94 TYR B CD1 1 ATOM 4920 C CD2 . TYR B 1 94 ? -50.610 -29.253 77.917 1.00 70.72 ? 94 TYR B CD2 1 ATOM 4921 C CE1 . TYR B 1 94 ? -51.122 -31.956 77.510 1.00 70.66 ? 94 TYR B CE1 1 ATOM 4922 C CE2 . TYR B 1 94 ? -50.787 -30.088 79.009 1.00 70.66 ? 94 TYR B CE2 1 ATOM 4923 C CZ . TYR B 1 94 ? -51.036 -31.438 78.793 1.00 71.02 ? 94 TYR B CZ 1 ATOM 4924 O OH . TYR B 1 94 ? -51.209 -32.281 79.854 1.00 71.51 ? 94 TYR B OH 1 ATOM 4925 N N . LEU B 1 95 ? -51.139 -26.472 73.611 1.00 67.84 ? 95 LEU B N 1 ATOM 4926 C CA . LEU B 1 95 ? -50.976 -25.617 72.443 1.00 67.05 ? 95 LEU B CA 1 ATOM 4927 C C . LEU B 1 95 ? -49.719 -24.753 72.572 1.00 66.77 ? 95 LEU B C 1 ATOM 4928 O O . LEU B 1 95 ? -49.203 -24.534 73.661 1.00 66.57 ? 95 LEU B O 1 ATOM 4929 C CB . LEU B 1 95 ? -52.224 -24.751 72.244 1.00 66.70 ? 95 LEU B CB 1 ATOM 4930 C CG . LEU B 1 95 ? -52.636 -23.905 73.440 1.00 66.25 ? 95 LEU B CG 1 ATOM 4931 C CD1 . LEU B 1 95 ? -51.639 -22.771 73.604 1.00 65.96 ? 95 LEU B CD1 1 ATOM 4932 C CD2 . LEU B 1 95 ? -54.026 -23.349 73.245 1.00 65.89 ? 95 LEU B CD2 1 ATOM 4933 N N . ASN B 1 96 ? -49.228 -24.269 71.445 1.00 66.60 ? 96 ASN B N 1 ATOM 4934 C CA . ASN B 1 96 ? -48.020 -23.498 71.441 1.00 66.62 ? 96 ASN B CA 1 ATOM 4935 C C . ASN B 1 96 ? -48.309 -22.077 70.998 1.00 66.89 ? 96 ASN B C 1 ATOM 4936 O O . ASN B 1 96 ? -49.281 -21.831 70.281 1.00 67.06 ? 96 ASN B O 1 ATOM 4937 C CB . ASN B 1 96 ? -47.022 -24.145 70.496 1.00 66.61 ? 96 ASN B CB 1 ATOM 4938 C CG . ASN B 1 96 ? -47.073 -25.664 70.558 1.00 67.03 ? 96 ASN B CG 1 ATOM 4939 O OD1 . ASN B 1 96 ? -46.794 -26.272 71.608 1.00 67.10 ? 96 ASN B OD1 1 ATOM 4940 N ND2 . ASN B 1 96 ? -47.441 -26.291 69.431 1.00 66.84 ? 96 ASN B ND2 1 ATOM 4941 N N . VAL B 1 97 ? -47.466 -21.147 71.439 1.00 66.95 ? 97 VAL B N 1 ATOM 4942 C CA . VAL B 1 97 ? -47.493 -19.768 70.979 1.00 66.75 ? 97 VAL B CA 1 ATOM 4943 C C . VAL B 1 97 ? -46.076 -19.337 70.653 1.00 67.13 ? 97 VAL B C 1 ATOM 4944 O O . VAL B 1 97 ? -45.141 -19.726 71.321 1.00 67.29 ? 97 VAL B O 1 ATOM 4945 C CB . VAL B 1 97 ? -48.023 -18.850 72.058 1.00 66.59 ? 97 VAL B CB 1 ATOM 4946 C CG1 . VAL B 1 97 ? -47.835 -17.392 71.645 1.00 66.23 ? 97 VAL B CG1 1 ATOM 4947 C CG2 . VAL B 1 97 ? -49.475 -19.182 72.351 1.00 66.08 ? 97 VAL B CG2 1 ATOM 4948 N N . TRP B 1 98 ? -45.900 -18.552 69.611 1.00 67.86 ? 98 TRP B N 1 ATOM 4949 C CA . TRP B 1 98 ? -44.583 -18.010 69.329 1.00 68.78 ? 98 TRP B CA 1 ATOM 4950 C C . TRP B 1 98 ? -44.789 -16.542 69.141 1.00 69.69 ? 98 TRP B C 1 ATOM 4951 O O . TRP B 1 98 ? -45.298 -16.108 68.097 1.00 70.01 ? 98 TRP B O 1 ATOM 4952 C CB . TRP B 1 98 ? -44.001 -18.535 68.015 1.00 68.49 ? 98 TRP B CB 1 ATOM 4953 C CG . TRP B 1 98 ? -43.491 -19.937 67.999 1.00 68.09 ? 98 TRP B CG 1 ATOM 4954 C CD1 . TRP B 1 98 ? -42.195 -20.333 68.144 1.00 67.66 ? 98 TRP B CD1 1 ATOM 4955 C CD2 . TRP B 1 98 ? -44.255 -21.132 67.745 1.00 67.61 ? 98 TRP B CD2 1 ATOM 4956 N NE1 . TRP B 1 98 ? -42.106 -21.704 68.018 1.00 68.07 ? 98 TRP B NE1 1 ATOM 4957 C CE2 . TRP B 1 98 ? -43.358 -22.214 67.776 1.00 67.39 ? 98 TRP B CE2 1 ATOM 4958 C CE3 . TRP B 1 98 ? -45.611 -21.387 67.506 1.00 66.61 ? 98 TRP B CE3 1 ATOM 4959 C CZ2 . TRP B 1 98 ? -43.772 -23.529 67.580 1.00 67.28 ? 98 TRP B CZ2 1 ATOM 4960 C CZ3 . TRP B 1 98 ? -46.020 -22.695 67.320 1.00 65.97 ? 98 TRP B CZ3 1 ATOM 4961 C CH2 . TRP B 1 98 ? -45.106 -23.747 67.357 1.00 66.36 ? 98 TRP B CH2 1 ATOM 4962 N N . ILE B 1 99 ? -44.405 -15.757 70.132 1.00 70.73 ? 99 ILE B N 1 ATOM 4963 C CA . ILE B 1 99 ? -44.480 -14.310 69.968 1.00 71.83 ? 99 ILE B CA 1 ATOM 4964 C C . ILE B 1 99 ? -43.102 -13.775 69.540 1.00 72.43 ? 99 ILE B C 1 ATOM 4965 O O . ILE B 1 99 ? -42.074 -14.261 70.015 1.00 72.64 ? 99 ILE B O 1 ATOM 4966 C CB . ILE B 1 99 ? -44.997 -13.657 71.247 1.00 71.65 ? 99 ILE B CB 1 ATOM 4967 C CG1 . ILE B 1 99 ? -44.022 -13.932 72.382 1.00 72.34 ? 99 ILE B CG1 1 ATOM 4968 C CG2 . ILE B 1 99 ? -46.352 -14.234 71.614 1.00 71.47 ? 99 ILE B CG2 1 ATOM 4969 C CD1 . ILE B 1 99 ? -43.237 -12.719 72.801 1.00 74.37 ? 99 ILE B CD1 1 ATOM 4970 N N . PRO B 1 100 ? -43.066 -12.800 68.616 1.00 73.10 ? 100 PRO B N 1 ATOM 4971 C CA . PRO B 1 100 ? -41.724 -12.322 68.286 1.00 73.82 ? 100 PRO B CA 1 ATOM 4972 C C . PRO B 1 100 ? -41.187 -11.499 69.466 1.00 74.79 ? 100 PRO B C 1 ATOM 4973 O O . PRO B 1 100 ? -41.984 -11.012 70.297 1.00 75.12 ? 100 PRO B O 1 ATOM 4974 C CB . PRO B 1 100 ? -41.959 -11.415 67.076 1.00 73.49 ? 100 PRO B CB 1 ATOM 4975 C CG . PRO B 1 100 ? -43.354 -10.880 67.273 1.00 73.13 ? 100 PRO B CG 1 ATOM 4976 C CD . PRO B 1 100 ? -44.120 -11.885 68.141 1.00 73.16 ? 100 PRO B CD 1 ATOM 4977 N N . ALA B 1 101 ? -39.862 -11.354 69.559 1.00 75.27 ? 101 ALA B N 1 ATOM 4978 C CA . ALA B 1 101 ? -39.263 -10.476 70.574 1.00 75.53 ? 101 ALA B CA 1 ATOM 4979 C C . ALA B 1 101 ? -38.564 -9.321 69.894 1.00 75.80 ? 101 ALA B C 1 ATOM 4980 O O . ALA B 1 101 ? -37.783 -9.542 68.976 1.00 76.09 ? 101 ALA B O 1 ATOM 4981 C CB . ALA B 1 101 ? -38.287 -11.241 71.425 1.00 75.48 ? 101 ALA B CB 1 ATOM 4982 N N . PRO B 1 102 ? -38.802 -8.090 70.370 1.00 76.13 ? 102 PRO B N 1 ATOM 4983 C CA . PRO B 1 102 ? -39.532 -7.779 71.606 1.00 76.45 ? 102 PRO B CA 1 ATOM 4984 C C . PRO B 1 102 ? -41.038 -7.986 71.500 1.00 76.64 ? 102 PRO B C 1 ATOM 4985 O O . PRO B 1 102 ? -41.626 -7.761 70.435 1.00 76.57 ? 102 PRO B O 1 ATOM 4986 C CB . PRO B 1 102 ? -39.244 -6.283 71.832 1.00 76.27 ? 102 PRO B CB 1 ATOM 4987 C CG . PRO B 1 102 ? -38.212 -5.891 70.773 1.00 76.64 ? 102 PRO B CG 1 ATOM 4988 C CD . PRO B 1 102 ? -38.375 -6.874 69.662 1.00 76.15 ? 102 PRO B CD 1 ATOM 4989 N N . LYS B 1 103 ? -41.644 -8.410 72.611 1.00 76.68 ? 103 LYS B N 1 ATOM 4990 C CA . LYS B 1 103 ? -43.096 -8.513 72.722 1.00 76.67 ? 103 LYS B CA 1 ATOM 4991 C C . LYS B 1 103 ? -43.789 -7.405 71.905 1.00 77.03 ? 103 LYS B C 1 ATOM 4992 O O . LYS B 1 103 ? -43.496 -6.224 72.077 1.00 76.96 ? 103 LYS B O 1 ATOM 4993 C CB . LYS B 1 103 ? -43.490 -8.424 74.190 1.00 76.30 ? 103 LYS B CB 1 ATOM 4994 C CG . LYS B 1 103 ? -44.960 -8.588 74.463 1.00 75.96 ? 103 LYS B CG 1 ATOM 4995 C CD . LYS B 1 103 ? -45.208 -8.433 75.953 1.00 75.43 ? 103 LYS B CD 1 ATOM 4996 C CE . LYS B 1 103 ? -46.364 -9.292 76.417 1.00 75.14 ? 103 LYS B CE 1 ATOM 4997 N NZ . LYS B 1 103 ? -47.653 -8.583 76.239 1.00 75.34 ? 103 LYS B NZ 1 ATOM 4998 N N . PRO B 1 104 ? -44.703 -7.784 70.997 1.00 77.34 ? 104 PRO B N 1 ATOM 4999 C CA . PRO B 1 104 ? -45.291 -6.776 70.128 1.00 77.23 ? 104 PRO B CA 1 ATOM 5000 C C . PRO B 1 104 ? -46.551 -6.207 70.773 1.00 77.29 ? 104 PRO B C 1 ATOM 5001 O O . PRO B 1 104 ? -47.069 -6.778 71.755 1.00 77.29 ? 104 PRO B O 1 ATOM 5002 C CB . PRO B 1 104 ? -45.627 -7.579 68.868 1.00 77.10 ? 104 PRO B CB 1 ATOM 5003 C CG . PRO B 1 104 ? -45.916 -8.986 69.385 1.00 77.09 ? 104 PRO B CG 1 ATOM 5004 C CD . PRO B 1 104 ? -45.313 -9.110 70.777 1.00 77.44 ? 104 PRO B CD 1 ATOM 5005 N N . LYS B 1 105 ? -47.042 -5.100 70.227 1.00 77.30 ? 105 LYS B N 1 ATOM 5006 C CA . LYS B 1 105 ? -48.173 -4.405 70.828 1.00 77.60 ? 105 LYS B CA 1 ATOM 5007 C C . LYS B 1 105 ? -49.485 -5.097 70.535 1.00 77.58 ? 105 LYS B C 1 ATOM 5008 O O . LYS B 1 105 ? -50.205 -5.529 71.446 1.00 77.68 ? 105 LYS B O 1 ATOM 5009 C CB . LYS B 1 105 ? -48.260 -2.978 70.306 1.00 77.71 ? 105 LYS B CB 1 ATOM 5010 C CG . LYS B 1 105 ? -47.066 -2.099 70.658 1.00 78.90 ? 105 LYS B CG 1 ATOM 5011 C CD . LYS B 1 105 ? -47.063 -1.694 72.131 1.00 80.07 ? 105 LYS B CD 1 ATOM 5012 C CE . LYS B 1 105 ? -46.128 -0.527 72.363 1.00 80.56 ? 105 LYS B CE 1 ATOM 5013 N NZ . LYS B 1 105 ? -45.317 -0.776 73.572 1.00 81.99 ? 105 LYS B NZ 1 ATOM 5014 N N . ASN B 1 106 ? -49.785 -5.213 69.247 1.00 77.48 ? 106 ASN B N 1 ATOM 5015 C CA . ASN B 1 106 ? -51.093 -5.693 68.819 1.00 77.37 ? 106 ASN B CA 1 ATOM 5016 C C . ASN B 1 106 ? -51.065 -6.697 67.658 1.00 76.12 ? 106 ASN B C 1 ATOM 5017 O O . ASN B 1 106 ? -51.957 -6.672 66.812 1.00 76.38 ? 106 ASN B O 1 ATOM 5018 C CB . ASN B 1 106 ? -51.944 -4.494 68.427 1.00 78.02 ? 106 ASN B CB 1 ATOM 5019 C CG . ASN B 1 106 ? -53.303 -4.534 69.045 1.00 81.36 ? 106 ASN B CG 1 ATOM 5020 O OD1 . ASN B 1 106 ? -53.701 -5.543 69.623 1.00 83.02 ? 106 ASN B OD1 1 ATOM 5021 N ND2 . ASN B 1 106 ? -54.023 -3.414 68.951 1.00 87.47 ? 106 ASN B ND2 1 ATOM 5022 N N . ALA B 1 107 ? -50.069 -7.587 67.637 1.00 74.60 ? 107 ALA B N 1 ATOM 5023 C CA . ALA B 1 107 ? -49.783 -8.457 66.472 1.00 72.98 ? 107 ALA B CA 1 ATOM 5024 C C . ALA B 1 107 ? -50.974 -9.275 66.001 1.00 71.84 ? 107 ALA B C 1 ATOM 5025 O O . ALA B 1 107 ? -51.745 -9.779 66.835 1.00 71.80 ? 107 ALA B O 1 ATOM 5026 C CB . ALA B 1 107 ? -48.603 -9.391 66.761 1.00 73.07 ? 107 ALA B CB 1 ATOM 5027 N N . THR B 1 108 ? -51.119 -9.390 64.671 1.00 70.07 ? 108 THR B N 1 ATOM 5028 C CA . THR B 1 108 ? -52.078 -10.310 64.049 1.00 68.48 ? 108 THR B CA 1 ATOM 5029 C C . THR B 1 108 ? -51.660 -11.743 64.386 1.00 67.79 ? 108 THR B C 1 ATOM 5030 O O . THR B 1 108 ? -50.476 -12.103 64.262 1.00 67.90 ? 108 THR B O 1 ATOM 5031 C CB . THR B 1 108 ? -52.088 -10.194 62.497 1.00 68.60 ? 108 THR B CB 1 ATOM 5032 O OG1 . THR B 1 108 ? -52.879 -9.079 62.058 1.00 67.58 ? 108 THR B OG1 1 ATOM 5033 C CG2 . THR B 1 108 ? -52.655 -11.468 61.873 1.00 68.76 ? 108 THR B CG2 1 ATOM 5034 N N . VAL B 1 109 ? -52.620 -12.565 64.803 1.00 66.51 ? 109 VAL B N 1 ATOM 5035 C CA . VAL B 1 109 ? -52.315 -13.941 65.194 1.00 65.06 ? 109 VAL B CA 1 ATOM 5036 C C . VAL B 1 109 ? -52.678 -14.981 64.128 1.00 64.27 ? 109 VAL B C 1 ATOM 5037 O O . VAL B 1 109 ? -53.751 -14.916 63.522 1.00 64.26 ? 109 VAL B O 1 ATOM 5038 C CB . VAL B 1 109 ? -53.121 -14.321 66.427 1.00 65.08 ? 109 VAL B CB 1 ATOM 5039 C CG1 . VAL B 1 109 ? -52.634 -15.663 66.961 1.00 64.73 ? 109 VAL B CG1 1 ATOM 5040 C CG2 . VAL B 1 109 ? -53.059 -13.226 67.458 1.00 64.37 ? 109 VAL B CG2 1 ATOM 5041 N N . LEU B 1 110 ? -51.809 -15.965 63.935 1.00 63.14 ? 110 LEU B N 1 ATOM 5042 C CA . LEU B 1 110 ? -52.099 -17.092 63.030 1.00 62.30 ? 110 LEU B CA 1 ATOM 5043 C C . LEU B 1 110 ? -52.262 -18.378 63.809 1.00 61.55 ? 110 LEU B C 1 ATOM 5044 O O . LEU B 1 110 ? -51.356 -18.788 64.518 1.00 61.90 ? 110 LEU B O 1 ATOM 5045 C CB . LEU B 1 110 ? -50.966 -17.311 62.016 1.00 62.21 ? 110 LEU B CB 1 ATOM 5046 C CG . LEU B 1 110 ? -50.999 -16.513 60.707 1.00 62.03 ? 110 LEU B CG 1 ATOM 5047 C CD1 . LEU B 1 110 ? -51.465 -15.077 60.952 1.00 62.90 ? 110 LEU B CD1 1 ATOM 5048 C CD2 . LEU B 1 110 ? -49.640 -16.512 60.022 1.00 60.18 ? 110 LEU B CD2 1 ATOM 5049 N N . ILE B 1 111 ? -53.391 -19.047 63.664 1.00 60.52 ? 111 ILE B N 1 ATOM 5050 C CA . ILE B 1 111 ? -53.533 -20.346 64.300 1.00 59.64 ? 111 ILE B CA 1 ATOM 5051 C C . ILE B 1 111 ? -53.416 -21.524 63.323 1.00 59.84 ? 111 ILE B C 1 ATOM 5052 O O . ILE B 1 111 ? -54.202 -21.666 62.372 1.00 60.14 ? 111 ILE B O 1 ATOM 5053 C CB . ILE B 1 111 ? -54.848 -20.434 64.997 1.00 59.22 ? 111 ILE B CB 1 ATOM 5054 C CG1 . ILE B 1 111 ? -54.987 -19.235 65.925 1.00 58.93 ? 111 ILE B CG1 1 ATOM 5055 C CG2 . ILE B 1 111 ? -54.927 -21.733 65.735 1.00 58.52 ? 111 ILE B CG2 1 ATOM 5056 C CD1 . ILE B 1 111 ? -56.319 -19.148 66.616 1.00 58.08 ? 111 ILE B CD1 1 ATOM 5057 N N . TRP B 1 112 ? -52.436 -22.382 63.548 1.00 59.42 ? 112 TRP B N 1 ATOM 5058 C CA . TRP B 1 112 ? -52.293 -23.530 62.684 1.00 59.37 ? 112 TRP B CA 1 ATOM 5059 C C . TRP B 1 112 ? -53.144 -24.747 63.089 1.00 59.41 ? 112 TRP B C 1 ATOM 5060 O O . TRP B 1 112 ? -53.326 -25.041 64.284 1.00 59.66 ? 112 TRP B O 1 ATOM 5061 C CB . TRP B 1 112 ? -50.848 -23.932 62.637 1.00 59.37 ? 112 TRP B CB 1 ATOM 5062 C CG . TRP B 1 112 ? -50.644 -25.121 61.827 1.00 60.26 ? 112 TRP B CG 1 ATOM 5063 C CD1 . TRP B 1 112 ? -50.382 -26.380 62.270 1.00 60.59 ? 112 TRP B CD1 1 ATOM 5064 C CD2 . TRP B 1 112 ? -50.695 -25.186 60.407 1.00 61.50 ? 112 TRP B CD2 1 ATOM 5065 N NE1 . TRP B 1 112 ? -50.241 -27.231 61.201 1.00 62.52 ? 112 TRP B NE1 1 ATOM 5066 C CE2 . TRP B 1 112 ? -50.432 -26.521 60.041 1.00 62.57 ? 112 TRP B CE2 1 ATOM 5067 C CE3 . TRP B 1 112 ? -50.940 -24.246 59.406 1.00 61.52 ? 112 TRP B CE3 1 ATOM 5068 C CZ2 . TRP B 1 112 ? -50.399 -26.941 58.702 1.00 63.19 ? 112 TRP B CZ2 1 ATOM 5069 C CZ3 . TRP B 1 112 ? -50.907 -24.661 58.081 1.00 62.15 ? 112 TRP B CZ3 1 ATOM 5070 C CH2 . TRP B 1 112 ? -50.636 -25.996 57.739 1.00 62.45 ? 112 TRP B CH2 1 ATOM 5071 N N . ILE B 1 113 ? -53.668 -25.459 62.097 1.00 59.05 ? 113 ILE B N 1 ATOM 5072 C CA . ILE B 1 113 ? -54.356 -26.702 62.378 1.00 58.71 ? 113 ILE B CA 1 ATOM 5073 C C . ILE B 1 113 ? -53.777 -27.839 61.531 1.00 59.44 ? 113 ILE B C 1 ATOM 5074 O O . ILE B 1 113 ? -53.795 -27.785 60.296 1.00 59.96 ? 113 ILE B O 1 ATOM 5075 C CB . ILE B 1 113 ? -55.827 -26.568 62.127 1.00 58.14 ? 113 ILE B CB 1 ATOM 5076 C CG1 . ILE B 1 113 ? -56.389 -25.426 62.980 1.00 57.39 ? 113 ILE B CG1 1 ATOM 5077 C CG2 . ILE B 1 113 ? -56.506 -27.868 62.441 1.00 58.11 ? 113 ILE B CG2 1 ATOM 5078 C CD1 . ILE B 1 113 ? -57.905 -25.230 62.876 1.00 55.04 ? 113 ILE B CD1 1 ATOM 5079 N N . TYR B 1 114 ? -53.248 -28.869 62.188 1.00 59.54 ? 114 TYR B N 1 ATOM 5080 C CA . TYR B 1 114 ? -52.514 -29.908 61.472 1.00 59.49 ? 114 TYR B CA 1 ATOM 5081 C C . TYR B 1 114 ? -53.468 -30.835 60.728 1.00 59.70 ? 114 TYR B C 1 ATOM 5082 O O . TYR B 1 114 ? -54.572 -31.117 61.217 1.00 59.49 ? 114 TYR B O 1 ATOM 5083 C CB . TYR B 1 114 ? -51.540 -30.695 62.407 1.00 59.53 ? 114 TYR B CB 1 ATOM 5084 C CG . TYR B 1 114 ? -52.169 -31.329 63.643 1.00 59.33 ? 114 TYR B CG 1 ATOM 5085 C CD1 . TYR B 1 114 ? -52.877 -32.530 63.558 1.00 59.21 ? 114 TYR B CD1 1 ATOM 5086 C CD2 . TYR B 1 114 ? -52.052 -30.719 64.896 1.00 59.09 ? 114 TYR B CD2 1 ATOM 5087 C CE1 . TYR B 1 114 ? -53.467 -33.105 64.699 1.00 59.09 ? 114 TYR B CE1 1 ATOM 5088 C CE2 . TYR B 1 114 ? -52.639 -31.271 66.035 1.00 59.15 ? 114 TYR B CE2 1 ATOM 5089 C CZ . TYR B 1 114 ? -53.351 -32.463 65.941 1.00 59.30 ? 114 TYR B CZ 1 ATOM 5090 O OH . TYR B 1 114 ? -53.934 -33.010 67.087 1.00 57.89 ? 114 TYR B OH 1 ATOM 5091 N N . GLY B 1 115 ? -53.034 -31.291 59.548 1.00 59.80 ? 115 GLY B N 1 ATOM 5092 C CA . GLY B 1 115 ? -53.731 -32.350 58.809 1.00 60.14 ? 115 GLY B CA 1 ATOM 5093 C C . GLY B 1 115 ? -53.471 -33.780 59.302 1.00 60.59 ? 115 GLY B C 1 ATOM 5094 O O . GLY B 1 115 ? -53.005 -33.992 60.434 1.00 60.41 ? 115 GLY B O 1 ATOM 5095 N N . GLY B 1 116 ? -53.778 -34.769 58.455 1.00 60.84 ? 116 GLY B N 1 ATOM 5096 C CA . GLY B 1 116 ? -53.679 -36.174 58.850 1.00 60.92 ? 116 GLY B CA 1 ATOM 5097 C C . GLY B 1 116 ? -55.052 -36.817 58.986 1.00 61.36 ? 116 GLY B C 1 ATOM 5098 O O . GLY B 1 116 ? -55.361 -37.414 60.011 1.00 61.35 ? 116 GLY B O 1 ATOM 5099 N N . GLY B 1 117 ? -55.889 -36.670 57.960 1.00 61.71 ? 117 GLY B N 1 ATOM 5100 C CA . GLY B 1 117 ? -57.183 -37.356 57.894 1.00 61.94 ? 117 GLY B CA 1 ATOM 5101 C C . GLY B 1 117 ? -58.011 -37.482 59.167 1.00 62.36 ? 117 GLY B C 1 ATOM 5102 O O . GLY B 1 117 ? -58.833 -38.398 59.284 1.00 62.24 ? 117 GLY B O 1 ATOM 5103 N N . PHE B 1 118 ? -57.828 -36.558 60.111 1.00 62.88 ? 118 PHE B N 1 ATOM 5104 C CA . PHE B 1 118 ? -58.496 -36.634 61.428 1.00 63.65 ? 118 PHE B CA 1 ATOM 5105 C C . PHE B 1 118 ? -58.079 -37.895 62.193 1.00 64.23 ? 118 PHE B C 1 ATOM 5106 O O . PHE B 1 118 ? -58.709 -38.279 63.178 1.00 64.41 ? 118 PHE B O 1 ATOM 5107 C CB . PHE B 1 118 ? -60.026 -36.568 61.290 1.00 63.36 ? 118 PHE B CB 1 ATOM 5108 C CG . PHE B 1 118 ? -60.523 -35.283 60.666 1.00 63.96 ? 118 PHE B CG 1 ATOM 5109 C CD1 . PHE B 1 118 ? -60.576 -34.111 61.406 1.00 63.72 ? 118 PHE B CD1 1 ATOM 5110 C CD2 . PHE B 1 118 ? -60.913 -35.237 59.331 1.00 63.74 ? 118 PHE B CD2 1 ATOM 5111 C CE1 . PHE B 1 118 ? -61.022 -32.913 60.829 1.00 63.05 ? 118 PHE B CE1 1 ATOM 5112 C CE2 . PHE B 1 118 ? -61.365 -34.053 58.764 1.00 62.87 ? 118 PHE B CE2 1 ATOM 5113 C CZ . PHE B 1 118 ? -61.418 -32.888 59.517 1.00 62.49 ? 118 PHE B CZ 1 ATOM 5114 N N . GLN B 1 119 ? -57.022 -38.545 61.726 1.00 64.82 ? 119 GLN B N 1 ATOM 5115 C CA . GLN B 1 119 ? -56.592 -39.801 62.306 1.00 65.57 ? 119 GLN B CA 1 ATOM 5116 C C . GLN B 1 119 ? -55.207 -39.607 62.932 1.00 66.29 ? 119 GLN B C 1 ATOM 5117 O O . GLN B 1 119 ? -54.851 -40.260 63.928 1.00 67.00 ? 119 GLN B O 1 ATOM 5118 C CB . GLN B 1 119 ? -56.525 -40.915 61.241 1.00 65.55 ? 119 GLN B CB 1 ATOM 5119 C CG . GLN B 1 119 ? -57.786 -41.148 60.439 1.00 66.17 ? 119 GLN B CG 1 ATOM 5120 C CD . GLN B 1 119 ? -59.038 -41.243 61.288 1.00 68.63 ? 119 GLN B CD 1 ATOM 5121 O OE1 . GLN B 1 119 ? -60.033 -40.584 60.996 1.00 69.47 ? 119 GLN B OE1 1 ATOM 5122 N NE2 . GLN B 1 119 ? -59.003 -42.064 62.340 1.00 69.90 ? 119 GLN B NE2 1 ATOM 5123 N N . THR B 1 120 ? -54.413 -38.717 62.347 1.00 66.27 ? 120 THR B N 1 ATOM 5124 C CA . THR B 1 120 ? -53.023 -38.587 62.746 1.00 65.86 ? 120 THR B CA 1 ATOM 5125 C C . THR B 1 120 ? -52.632 -37.129 62.799 1.00 66.04 ? 120 THR B C 1 ATOM 5126 O O . THR B 1 120 ? -53.417 -36.250 62.433 1.00 66.17 ? 120 THR B O 1 ATOM 5127 C CB . THR B 1 120 ? -52.081 -39.303 61.750 1.00 65.65 ? 120 THR B CB 1 ATOM 5128 O OG1 . THR B 1 120 ? -52.048 -38.578 60.510 1.00 65.45 ? 120 THR B OG1 1 ATOM 5129 C CG2 . THR B 1 120 ? -52.551 -40.728 61.501 1.00 64.89 ? 120 THR B CG2 1 ATOM 5130 N N . GLY B 1 121 ? -51.401 -36.882 63.242 1.00 66.20 ? 121 GLY B N 1 ATOM 5131 C CA . GLY B 1 121 ? -50.865 -35.523 63.315 1.00 66.04 ? 121 GLY B CA 1 ATOM 5132 C C . GLY B 1 121 ? -50.613 -34.944 64.702 1.00 65.75 ? 121 GLY B C 1 ATOM 5133 O O . GLY B 1 121 ? -51.107 -35.435 65.715 1.00 65.43 ? 121 GLY B O 1 ATOM 5134 N N . THR B 1 122 ? -49.827 -33.878 64.736 1.00 65.77 ? 122 THR B N 1 ATOM 5135 C CA . THR B 1 122 ? -49.480 -33.209 65.985 1.00 65.55 ? 122 THR B CA 1 ATOM 5136 C C . THR B 1 122 ? -48.801 -31.874 65.665 1.00 65.59 ? 122 THR B C 1 ATOM 5137 O O . THR B 1 122 ? -48.092 -31.743 64.644 1.00 65.72 ? 122 THR B O 1 ATOM 5138 C CB . THR B 1 122 ? -48.531 -34.053 66.844 1.00 65.15 ? 122 THR B CB 1 ATOM 5139 O OG1 . THR B 1 122 ? -48.442 -33.473 68.147 1.00 65.49 ? 122 THR B OG1 1 ATOM 5140 C CG2 . THR B 1 122 ? -47.149 -34.084 66.221 1.00 64.56 ? 122 THR B CG2 1 ATOM 5141 N N . SER B 1 123 ? -49.011 -30.899 66.540 1.00 65.20 ? 123 SER B N 1 ATOM 5142 C CA . SER B 1 123 ? -48.507 -29.562 66.315 1.00 65.16 ? 123 SER B CA 1 ATOM 5143 C C . SER B 1 123 ? -46.987 -29.461 66.386 1.00 65.53 ? 123 SER B C 1 ATOM 5144 O O . SER B 1 123 ? -46.393 -28.558 65.811 1.00 65.69 ? 123 SER B O 1 ATOM 5145 C CB . SER B 1 123 ? -49.118 -28.608 67.324 1.00 65.19 ? 123 SER B CB 1 ATOM 5146 O OG . SER B 1 123 ? -48.677 -28.930 68.622 1.00 64.23 ? 123 SER B OG 1 ATOM 5147 N N . SER B 1 124 ? -46.356 -30.399 67.075 1.00 65.83 ? 124 SER B N 1 ATOM 5148 C CA . SER B 1 124 ? -44.925 -30.314 67.354 1.00 65.73 ? 124 SER B CA 1 ATOM 5149 C C . SER B 1 124 ? -44.012 -30.619 66.165 1.00 65.78 ? 124 SER B C 1 ATOM 5150 O O . SER B 1 124 ? -42.799 -30.481 66.266 1.00 65.56 ? 124 SER B O 1 ATOM 5151 C CB . SER B 1 124 ? -44.584 -31.226 68.537 1.00 65.81 ? 124 SER B CB 1 ATOM 5152 O OG . SER B 1 124 ? -45.490 -32.329 68.631 1.00 65.69 ? 124 SER B OG 1 ATOM 5153 N N . LEU B 1 125 ? -44.592 -31.037 65.044 1.00 66.28 ? 125 LEU B N 1 ATOM 5154 C CA . LEU B 1 125 ? -43.793 -31.331 63.843 1.00 66.89 ? 125 LEU B CA 1 ATOM 5155 C C . LEU B 1 125 ? -42.856 -30.183 63.455 1.00 67.35 ? 125 LEU B C 1 ATOM 5156 O O . LEU B 1 125 ? -43.211 -29.005 63.530 1.00 67.16 ? 125 LEU B O 1 ATOM 5157 C CB . LEU B 1 125 ? -44.673 -31.667 62.634 1.00 66.60 ? 125 LEU B CB 1 ATOM 5158 C CG . LEU B 1 125 ? -45.431 -32.979 62.564 1.00 65.79 ? 125 LEU B CG 1 ATOM 5159 C CD1 . LEU B 1 125 ? -45.110 -33.602 61.219 1.00 65.25 ? 125 LEU B CD1 1 ATOM 5160 C CD2 . LEU B 1 125 ? -45.000 -33.905 63.678 1.00 66.16 ? 125 LEU B CD2 1 ATOM 5161 N N . HIS B 1 126 ? -41.665 -30.546 63.018 1.00 67.76 ? 126 HIS B N 1 ATOM 5162 C CA . HIS B 1 126 ? -40.686 -29.566 62.649 1.00 68.48 ? 126 HIS B CA 1 ATOM 5163 C C . HIS B 1 126 ? -41.259 -28.602 61.575 1.00 68.40 ? 126 HIS B C 1 ATOM 5164 O O . HIS B 1 126 ? -41.087 -27.362 61.654 1.00 68.17 ? 126 HIS B O 1 ATOM 5165 C CB . HIS B 1 126 ? -39.436 -30.306 62.184 1.00 68.95 ? 126 HIS B CB 1 ATOM 5166 C CG . HIS B 1 126 ? -38.366 -29.415 61.648 1.00 71.88 ? 126 HIS B CG 1 ATOM 5167 N ND1 . HIS B 1 126 ? -37.817 -28.382 62.384 1.00 74.23 ? 126 HIS B ND1 1 ATOM 5168 C CD2 . HIS B 1 126 ? -37.730 -29.409 60.449 1.00 74.38 ? 126 HIS B CD2 1 ATOM 5169 C CE1 . HIS B 1 126 ? -36.894 -27.773 61.658 1.00 75.46 ? 126 HIS B CE1 1 ATOM 5170 N NE2 . HIS B 1 126 ? -36.819 -28.377 60.479 1.00 76.00 ? 126 HIS B NE2 1 ATOM 5171 N N . VAL B 1 127 ? -41.973 -29.171 60.598 1.00 68.34 ? 127 VAL B N 1 ATOM 5172 C CA . VAL B 1 127 ? -42.599 -28.389 59.515 1.00 67.96 ? 127 VAL B CA 1 ATOM 5173 C C . VAL B 1 127 ? -43.694 -27.405 59.951 1.00 67.86 ? 127 VAL B C 1 ATOM 5174 O O . VAL B 1 127 ? -44.126 -26.565 59.167 1.00 67.71 ? 127 VAL B O 1 ATOM 5175 C CB . VAL B 1 127 ? -43.223 -29.305 58.479 1.00 67.88 ? 127 VAL B CB 1 ATOM 5176 C CG1 . VAL B 1 127 ? -42.213 -29.664 57.402 1.00 67.78 ? 127 VAL B CG1 1 ATOM 5177 C CG2 . VAL B 1 127 ? -43.782 -30.527 59.164 1.00 67.82 ? 127 VAL B CG2 1 ATOM 5178 N N . TYR B 1 128 ? -44.154 -27.525 61.191 1.00 67.93 ? 128 TYR B N 1 ATOM 5179 C CA . TYR B 1 128 ? -45.120 -26.570 61.751 1.00 67.80 ? 128 TYR B CA 1 ATOM 5180 C C . TYR B 1 128 ? -44.475 -25.624 62.769 1.00 68.02 ? 128 TYR B C 1 ATOM 5181 O O . TYR B 1 128 ? -45.111 -25.269 63.767 1.00 67.67 ? 128 TYR B O 1 ATOM 5182 C CB . TYR B 1 128 ? -46.275 -27.303 62.456 1.00 67.54 ? 128 TYR B CB 1 ATOM 5183 C CG . TYR B 1 128 ? -46.925 -28.429 61.673 1.00 66.80 ? 128 TYR B CG 1 ATOM 5184 C CD1 . TYR B 1 128 ? -46.935 -28.425 60.278 1.00 65.56 ? 128 TYR B CD1 1 ATOM 5185 C CD2 . TYR B 1 128 ? -47.552 -29.487 62.341 1.00 66.03 ? 128 TYR B CD2 1 ATOM 5186 C CE1 . TYR B 1 128 ? -47.539 -29.452 59.571 1.00 65.21 ? 128 TYR B CE1 1 ATOM 5187 C CE2 . TYR B 1 128 ? -48.152 -30.519 61.644 1.00 65.68 ? 128 TYR B CE2 1 ATOM 5188 C CZ . TYR B 1 128 ? -48.146 -30.499 60.256 1.00 65.22 ? 128 TYR B CZ 1 ATOM 5189 O OH . TYR B 1 128 ? -48.747 -31.523 59.556 1.00 63.06 ? 128 TYR B OH 1 ATOM 5190 N N . ASP B 1 129 ? -43.220 -25.231 62.538 1.00 68.41 ? 129 ASP B N 1 ATOM 5191 C CA . ASP B 1 129 ? -42.501 -24.435 63.543 1.00 68.90 ? 129 ASP B CA 1 ATOM 5192 C C . ASP B 1 129 ? -42.742 -22.934 63.388 1.00 68.82 ? 129 ASP B C 1 ATOM 5193 O O . ASP B 1 129 ? -42.178 -22.280 62.498 1.00 68.37 ? 129 ASP B O 1 ATOM 5194 C CB . ASP B 1 129 ? -41.002 -24.733 63.518 1.00 69.30 ? 129 ASP B CB 1 ATOM 5195 C CG . ASP B 1 129 ? -40.301 -24.340 64.825 1.00 70.06 ? 129 ASP B CG 1 ATOM 5196 O OD1 . ASP B 1 129 ? -40.903 -23.591 65.643 1.00 70.22 ? 129 ASP B OD1 1 ATOM 5197 O OD2 . ASP B 1 129 ? -39.141 -24.785 65.017 1.00 70.69 ? 129 ASP B OD2 1 ATOM 5198 N N . GLY B 1 130 ? -43.567 -22.394 64.280 1.00 68.83 ? 130 GLY B N 1 ATOM 5199 C CA . GLY B 1 130 ? -43.991 -21.002 64.186 1.00 69.07 ? 130 GLY B CA 1 ATOM 5200 C C . GLY B 1 130 ? -42.879 -20.002 64.470 1.00 69.36 ? 130 GLY B C 1 ATOM 5201 O O . GLY B 1 130 ? -43.042 -18.783 64.306 1.00 69.33 ? 130 GLY B O 1 ATOM 5202 N N . LYS B 1 131 ? -41.738 -20.510 64.911 1.00 69.44 ? 131 LYS B N 1 ATOM 5203 C CA . LYS B 1 131 ? -40.673 -19.632 65.340 1.00 69.43 ? 131 LYS B CA 1 ATOM 5204 C C . LYS B 1 131 ? -40.208 -18.689 64.205 1.00 69.51 ? 131 LYS B C 1 ATOM 5205 O O . LYS B 1 131 ? -39.985 -17.497 64.456 1.00 69.47 ? 131 LYS B O 1 ATOM 5206 C CB . LYS B 1 131 ? -39.527 -20.454 65.933 1.00 69.38 ? 131 LYS B CB 1 ATOM 5207 C CG . LYS B 1 131 ? -38.541 -20.912 64.925 1.00 69.60 ? 131 LYS B CG 1 ATOM 5208 C CD . LYS B 1 131 ? -37.580 -21.865 65.535 1.00 70.42 ? 131 LYS B CD 1 ATOM 5209 C CE . LYS B 1 131 ? -36.318 -21.863 64.703 1.00 71.79 ? 131 LYS B CE 1 ATOM 5210 N NZ . LYS B 1 131 ? -35.571 -23.143 64.825 1.00 72.91 ? 131 LYS B NZ 1 ATOM 5211 N N . PHE B 1 132 ? -40.092 -19.199 62.970 1.00 69.43 ? 132 PHE B N 1 ATOM 5212 C CA . PHE B 1 132 ? -39.733 -18.348 61.806 1.00 69.54 ? 132 PHE B CA 1 ATOM 5213 C C . PHE B 1 132 ? -40.776 -17.260 61.455 1.00 68.89 ? 132 PHE B C 1 ATOM 5214 O O . PHE B 1 132 ? -40.429 -16.107 61.179 1.00 68.51 ? 132 PHE B O 1 ATOM 5215 C CB . PHE B 1 132 ? -39.449 -19.201 60.565 1.00 70.00 ? 132 PHE B CB 1 ATOM 5216 C CG . PHE B 1 132 ? -38.549 -20.360 60.833 1.00 72.78 ? 132 PHE B CG 1 ATOM 5217 C CD1 . PHE B 1 132 ? -37.172 -20.179 60.894 1.00 74.38 ? 132 PHE B CD1 1 ATOM 5218 C CD2 . PHE B 1 132 ? -39.075 -21.645 61.049 1.00 75.43 ? 132 PHE B CD2 1 ATOM 5219 C CE1 . PHE B 1 132 ? -36.318 -21.252 61.168 1.00 75.20 ? 132 PHE B CE1 1 ATOM 5220 C CE2 . PHE B 1 132 ? -38.232 -22.732 61.322 1.00 75.97 ? 132 PHE B CE2 1 ATOM 5221 C CZ . PHE B 1 132 ? -36.849 -22.531 61.378 1.00 76.41 ? 132 PHE B CZ 1 ATOM 5222 N N . LEU B 1 133 ? -42.051 -17.627 61.441 1.00 68.26 ? 133 LEU B N 1 ATOM 5223 C CA . LEU B 1 133 ? -43.076 -16.662 61.071 1.00 68.04 ? 133 LEU B CA 1 ATOM 5224 C C . LEU B 1 133 ? -43.101 -15.490 62.046 1.00 68.16 ? 133 LEU B C 1 ATOM 5225 O O . LEU B 1 133 ? -43.282 -14.326 61.633 1.00 68.06 ? 133 LEU B O 1 ATOM 5226 C CB . LEU B 1 133 ? -44.460 -17.319 60.965 1.00 68.00 ? 133 LEU B CB 1 ATOM 5227 C CG . LEU B 1 133 ? -44.714 -18.095 59.664 1.00 67.59 ? 133 LEU B CG 1 ATOM 5228 C CD1 . LEU B 1 133 ? -45.916 -18.989 59.832 1.00 67.23 ? 133 LEU B CD1 1 ATOM 5229 C CD2 . LEU B 1 133 ? -44.870 -17.164 58.451 1.00 65.52 ? 133 LEU B CD2 1 ATOM 5230 N N . ALA B 1 134 ? -42.919 -15.797 63.338 1.00 68.07 ? 134 ALA B N 1 ATOM 5231 C CA . ALA B 1 134 ? -42.898 -14.755 64.375 1.00 67.81 ? 134 ALA B CA 1 ATOM 5232 C C . ALA B 1 134 ? -41.746 -13.837 64.059 1.00 67.74 ? 134 ALA B C 1 ATOM 5233 O O . ALA B 1 134 ? -41.909 -12.621 63.975 1.00 67.89 ? 134 ALA B O 1 ATOM 5234 C CB . ALA B 1 134 ? -42.733 -15.351 65.772 1.00 67.74 ? 134 ALA B CB 1 ATOM 5235 N N . ARG B 1 135 ? -40.580 -14.435 63.847 1.00 67.49 ? 135 ARG B N 1 ATOM 5236 C CA . ARG B 1 135 ? -39.387 -13.662 63.545 1.00 67.58 ? 135 ARG B CA 1 ATOM 5237 C C . ARG B 1 135 ? -39.590 -12.747 62.336 1.00 66.77 ? 135 ARG B C 1 ATOM 5238 O O . ARG B 1 135 ? -39.394 -11.545 62.425 1.00 66.87 ? 135 ARG B O 1 ATOM 5239 C CB . ARG B 1 135 ? -38.161 -14.582 63.356 1.00 68.12 ? 135 ARG B CB 1 ATOM 5240 C CG . ARG B 1 135 ? -36.817 -13.851 63.162 1.00 70.85 ? 135 ARG B CG 1 ATOM 5241 C CD . ARG B 1 135 ? -36.688 -12.608 64.077 1.00 75.34 ? 135 ARG B CD 1 ATOM 5242 N NE . ARG B 1 135 ? -35.352 -12.020 64.010 1.00 79.01 ? 135 ARG B NE 1 ATOM 5243 C CZ . ARG B 1 135 ? -34.850 -11.414 62.938 1.00 80.84 ? 135 ARG B CZ 1 ATOM 5244 N NH1 . ARG B 1 135 ? -35.567 -11.308 61.825 1.00 81.77 ? 135 ARG B NH1 1 ATOM 5245 N NH2 . ARG B 1 135 ? -33.622 -10.920 62.975 1.00 81.90 ? 135 ARG B NH2 1 ATOM 5246 N N . VAL B 1 136 ? -40.007 -13.307 61.214 1.00 66.02 ? 136 VAL B N 1 ATOM 5247 C CA . VAL B 1 136 ? -39.902 -12.567 59.984 1.00 65.13 ? 136 VAL B CA 1 ATOM 5248 C C . VAL B 1 136 ? -41.041 -11.585 59.723 1.00 65.21 ? 136 VAL B C 1 ATOM 5249 O O . VAL B 1 136 ? -40.800 -10.509 59.189 1.00 65.38 ? 136 VAL B O 1 ATOM 5250 C CB . VAL B 1 136 ? -39.793 -13.492 58.801 1.00 64.90 ? 136 VAL B CB 1 ATOM 5251 C CG1 . VAL B 1 136 ? -39.709 -12.657 57.532 1.00 64.21 ? 136 VAL B CG1 1 ATOM 5252 C CG2 . VAL B 1 136 ? -38.603 -14.426 58.980 1.00 64.12 ? 136 VAL B CG2 1 ATOM 5253 N N . GLU B 1 137 ? -42.272 -11.950 60.076 1.00 64.86 ? 137 GLU B N 1 ATOM 5254 C CA . GLU B 1 137 ? -43.432 -11.116 59.738 1.00 64.57 ? 137 GLU B CA 1 ATOM 5255 C C . GLU B 1 137 ? -44.023 -10.527 60.989 1.00 64.81 ? 137 GLU B C 1 ATOM 5256 O O . GLU B 1 137 ? -45.079 -9.907 60.980 1.00 64.61 ? 137 GLU B O 1 ATOM 5257 C CB . GLU B 1 137 ? -44.500 -11.920 58.979 1.00 64.31 ? 137 GLU B CB 1 ATOM 5258 C CG . GLU B 1 137 ? -44.093 -12.287 57.584 1.00 62.36 ? 137 GLU B CG 1 ATOM 5259 C CD . GLU B 1 137 ? -43.858 -11.054 56.749 1.00 61.61 ? 137 GLU B CD 1 ATOM 5260 O OE1 . GLU B 1 137 ? -44.720 -10.134 56.818 1.00 60.62 ? 137 GLU B OE1 1 ATOM 5261 O OE2 . GLU B 1 137 ? -42.822 -10.996 56.034 1.00 61.31 ? 137 GLU B OE2 1 ATOM 5262 N N . ARG B 1 138 ? -43.328 -10.748 62.081 1.00 65.48 ? 138 ARG B N 1 ATOM 5263 C CA . ARG B 1 138 ? -43.742 -10.174 63.333 1.00 66.38 ? 138 ARG B CA 1 ATOM 5264 C C . ARG B 1 138 ? -45.229 -10.409 63.580 1.00 65.65 ? 138 ARG B C 1 ATOM 5265 O O . ARG B 1 138 ? -45.982 -9.469 63.851 1.00 65.73 ? 138 ARG B O 1 ATOM 5266 C CB . ARG B 1 138 ? -43.356 -8.689 63.388 1.00 66.88 ? 138 ARG B CB 1 ATOM 5267 C CG . ARG B 1 138 ? -41.822 -8.502 63.309 1.00 71.17 ? 138 ARG B CG 1 ATOM 5268 C CD . ARG B 1 138 ? -41.332 -7.133 63.826 1.00 78.93 ? 138 ARG B CD 1 ATOM 5269 N NE . ARG B 1 138 ? -41.617 -6.953 65.259 1.00 85.19 ? 138 ARG B NE 1 ATOM 5270 C CZ . ARG B 1 138 ? -40.816 -7.353 66.257 1.00 87.84 ? 138 ARG B CZ 1 ATOM 5271 N NH1 . ARG B 1 138 ? -41.181 -7.148 67.529 1.00 87.44 ? 138 ARG B NH1 1 ATOM 5272 N NH2 . ARG B 1 138 ? -39.652 -7.958 65.988 1.00 88.63 ? 138 ARG B NH2 1 ATOM 5273 N N . VAL B 1 139 ? -45.637 -11.678 63.488 1.00 65.10 ? 139 VAL B N 1 ATOM 5274 C CA . VAL B 1 139 ? -46.959 -12.114 63.990 1.00 64.57 ? 139 VAL B CA 1 ATOM 5275 C C . VAL B 1 139 ? -46.840 -13.151 65.105 1.00 64.43 ? 139 VAL B C 1 ATOM 5276 O O . VAL B 1 139 ? -45.769 -13.739 65.331 1.00 64.68 ? 139 VAL B O 1 ATOM 5277 C CB . VAL B 1 139 ? -47.816 -12.753 62.905 1.00 64.21 ? 139 VAL B CB 1 ATOM 5278 C CG1 . VAL B 1 139 ? -48.327 -11.696 61.989 1.00 64.25 ? 139 VAL B CG1 1 ATOM 5279 C CG2 . VAL B 1 139 ? -47.011 -13.826 62.160 1.00 63.95 ? 139 VAL B CG2 1 ATOM 5280 N N . ILE B 1 140 ? -47.942 -13.384 65.803 1.00 63.78 ? 140 ILE B N 1 ATOM 5281 C CA . ILE B 1 140 ? -47.949 -14.430 66.793 1.00 63.16 ? 140 ILE B CA 1 ATOM 5282 C C . ILE B 1 140 ? -48.520 -15.655 66.123 1.00 62.77 ? 140 ILE B C 1 ATOM 5283 O O . ILE B 1 140 ? -49.535 -15.564 65.430 1.00 63.17 ? 140 ILE B O 1 ATOM 5284 C CB . ILE B 1 140 ? -48.830 -14.057 67.973 1.00 63.23 ? 140 ILE B CB 1 ATOM 5285 C CG1 . ILE B 1 140 ? -48.161 -12.938 68.773 1.00 62.78 ? 140 ILE B CG1 1 ATOM 5286 C CG2 . ILE B 1 140 ? -49.124 -15.310 68.814 1.00 63.04 ? 140 ILE B CG2 1 ATOM 5287 C CD1 . ILE B 1 140 ? -49.149 -12.038 69.502 1.00 63.25 ? 140 ILE B CD1 1 ATOM 5288 N N . VAL B 1 141 ? -47.869 -16.791 66.322 1.00 61.95 ? 141 VAL B N 1 ATOM 5289 C CA . VAL B 1 141 ? -48.345 -18.042 65.763 1.00 61.15 ? 141 VAL B CA 1 ATOM 5290 C C . VAL B 1 141 ? -48.790 -18.976 66.887 1.00 60.96 ? 141 VAL B C 1 ATOM 5291 O O . VAL B 1 141 ? -48.047 -19.237 67.830 1.00 61.16 ? 141 VAL B O 1 ATOM 5292 C CB . VAL B 1 141 ? -47.259 -18.764 64.950 1.00 60.93 ? 141 VAL B CB 1 ATOM 5293 C CG1 . VAL B 1 141 ? -47.857 -19.993 64.306 1.00 60.85 ? 141 VAL B CG1 1 ATOM 5294 C CG2 . VAL B 1 141 ? -46.666 -17.851 63.905 1.00 60.37 ? 141 VAL B CG2 1 ATOM 5295 N N . VAL B 1 142 ? -49.998 -19.488 66.786 1.00 60.33 ? 142 VAL B N 1 ATOM 5296 C CA . VAL B 1 142 ? -50.456 -20.453 67.747 1.00 59.98 ? 142 VAL B CA 1 ATOM 5297 C C . VAL B 1 142 ? -50.765 -21.725 66.992 1.00 60.32 ? 142 VAL B C 1 ATOM 5298 O O . VAL B 1 142 ? -51.265 -21.669 65.855 1.00 60.42 ? 142 VAL B O 1 ATOM 5299 C CB . VAL B 1 142 ? -51.756 -19.996 68.419 1.00 59.92 ? 142 VAL B CB 1 ATOM 5300 C CG1 . VAL B 1 142 ? -52.345 -21.118 69.282 1.00 59.02 ? 142 VAL B CG1 1 ATOM 5301 C CG2 . VAL B 1 142 ? -51.522 -18.741 69.220 1.00 59.87 ? 142 VAL B CG2 1 ATOM 5302 N N . SER B 1 143 ? -50.469 -22.869 67.610 1.00 60.39 ? 143 SER B N 1 ATOM 5303 C CA . SER B 1 143 ? -50.978 -24.147 67.121 1.00 60.38 ? 143 SER B CA 1 ATOM 5304 C C . SER B 1 143 ? -51.373 -24.986 68.313 1.00 60.68 ? 143 SER B C 1 ATOM 5305 O O . SER B 1 143 ? -50.860 -24.781 69.406 1.00 60.94 ? 143 SER B O 1 ATOM 5306 C CB . SER B 1 143 ? -49.946 -24.883 66.262 1.00 60.03 ? 143 SER B CB 1 ATOM 5307 O OG . SER B 1 143 ? -48.751 -25.116 66.979 1.00 59.97 ? 143 SER B OG 1 ATOM 5308 N N . MET B 1 144 ? -52.285 -25.924 68.099 1.00 60.97 ? 144 MET B N 1 ATOM 5309 C CA . MET B 1 144 ? -52.768 -26.754 69.181 1.00 61.31 ? 144 MET B CA 1 ATOM 5310 C C . MET B 1 144 ? -52.782 -28.179 68.709 1.00 61.44 ? 144 MET B C 1 ATOM 5311 O O . MET B 1 144 ? -52.592 -28.450 67.513 1.00 61.79 ? 144 MET B O 1 ATOM 5312 C CB . MET B 1 144 ? -54.198 -26.388 69.540 1.00 61.39 ? 144 MET B CB 1 ATOM 5313 C CG . MET B 1 144 ? -55.223 -27.083 68.643 1.00 62.21 ? 144 MET B CG 1 ATOM 5314 S SD . MET B 1 144 ? -55.282 -26.423 66.923 1.00 64.97 ? 144 MET B SD 1 ATOM 5315 C CE . MET B 1 144 ? -55.913 -24.770 67.243 1.00 63.13 ? 144 MET B CE 1 ATOM 5316 N N . ASN B 1 145 ? -53.022 -29.075 69.660 1.00 61.25 ? 145 ASN B N 1 ATOM 5317 C CA . ASN B 1 145 ? -53.265 -30.470 69.387 1.00 60.87 ? 145 ASN B CA 1 ATOM 5318 C C . ASN B 1 145 ? -54.710 -30.728 69.690 1.00 60.61 ? 145 ASN B C 1 ATOM 5319 O O . ASN B 1 145 ? -55.263 -30.121 70.624 1.00 60.53 ? 145 ASN B O 1 ATOM 5320 C CB . ASN B 1 145 ? -52.435 -31.336 70.314 1.00 61.10 ? 145 ASN B CB 1 ATOM 5321 C CG . ASN B 1 145 ? -50.971 -31.305 69.975 1.00 61.50 ? 145 ASN B CG 1 ATOM 5322 O OD1 . ASN B 1 145 ? -50.543 -30.626 69.027 1.00 60.10 ? 145 ASN B OD1 1 ATOM 5323 N ND2 . ASN B 1 145 ? -50.181 -32.067 70.743 1.00 62.29 ? 145 ASN B ND2 1 ATOM 5324 N N . TYR B 1 146 ? -55.316 -31.620 68.905 1.00 59.99 ? 146 TYR B N 1 ATOM 5325 C CA . TYR B 1 146 ? -56.720 -31.990 69.088 1.00 59.47 ? 146 TYR B CA 1 ATOM 5326 C C . TYR B 1 146 ? -56.804 -33.504 68.908 1.00 59.23 ? 146 TYR B C 1 ATOM 5327 O O . TYR B 1 146 ? -56.016 -34.105 68.152 1.00 58.80 ? 146 TYR B O 1 ATOM 5328 C CB . TYR B 1 146 ? -57.662 -31.231 68.104 1.00 59.10 ? 146 TYR B CB 1 ATOM 5329 C CG . TYR B 1 146 ? -57.326 -31.500 66.655 1.00 58.47 ? 146 TYR B CG 1 ATOM 5330 C CD1 . TYR B 1 146 ? -57.985 -32.497 65.938 1.00 57.34 ? 146 TYR B CD1 1 ATOM 5331 C CD2 . TYR B 1 146 ? -56.309 -30.791 66.012 1.00 57.90 ? 146 TYR B CD2 1 ATOM 5332 C CE1 . TYR B 1 146 ? -57.647 -32.779 64.600 1.00 57.16 ? 146 TYR B CE1 1 ATOM 5333 C CE2 . TYR B 1 146 ? -55.967 -31.056 64.686 1.00 57.87 ? 146 TYR B CE2 1 ATOM 5334 C CZ . TYR B 1 146 ? -56.644 -32.052 63.977 1.00 57.63 ? 146 TYR B CZ 1 ATOM 5335 O OH . TYR B 1 146 ? -56.307 -32.320 62.657 1.00 57.19 ? 146 TYR B OH 1 ATOM 5336 N N . ARG B 1 147 ? -57.742 -34.116 69.627 1.00 59.07 ? 147 ARG B N 1 ATOM 5337 C CA . ARG B 1 147 ? -57.940 -35.551 69.532 1.00 59.28 ? 147 ARG B CA 1 ATOM 5338 C C . ARG B 1 147 ? -58.275 -35.994 68.120 1.00 59.37 ? 147 ARG B C 1 ATOM 5339 O O . ARG B 1 147 ? -59.112 -35.394 67.477 1.00 59.38 ? 147 ARG B O 1 ATOM 5340 C CB . ARG B 1 147 ? -59.077 -35.966 70.447 1.00 59.28 ? 147 ARG B CB 1 ATOM 5341 C CG . ARG B 1 147 ? -58.707 -36.073 71.881 1.00 58.90 ? 147 ARG B CG 1 ATOM 5342 C CD . ARG B 1 147 ? -59.956 -36.197 72.689 1.00 59.10 ? 147 ARG B CD 1 ATOM 5343 N NE . ARG B 1 147 ? -60.577 -34.887 72.831 1.00 60.61 ? 147 ARG B NE 1 ATOM 5344 C CZ . ARG B 1 147 ? -61.732 -34.680 73.461 1.00 61.45 ? 147 ARG B CZ 1 ATOM 5345 N NH1 . ARG B 1 147 ? -62.368 -35.725 74.000 1.00 61.93 ? 147 ARG B NH1 1 ATOM 5346 N NH2 . ARG B 1 147 ? -62.251 -33.443 73.556 1.00 60.92 ? 147 ARG B NH2 1 ATOM 5347 N N . VAL B 1 148 ? -57.660 -37.072 67.659 1.00 59.86 ? 148 VAL B N 1 ATOM 5348 C CA . VAL B 1 148 ? -57.989 -37.606 66.348 1.00 60.48 ? 148 VAL B CA 1 ATOM 5349 C C . VAL B 1 148 ? -58.533 -39.032 66.453 1.00 61.09 ? 148 VAL B C 1 ATOM 5350 O O . VAL B 1 148 ? -58.693 -39.553 67.563 1.00 61.54 ? 148 VAL B O 1 ATOM 5351 C CB . VAL B 1 148 ? -56.761 -37.601 65.445 1.00 60.50 ? 148 VAL B CB 1 ATOM 5352 C CG1 . VAL B 1 148 ? -56.209 -36.198 65.350 1.00 60.58 ? 148 VAL B CG1 1 ATOM 5353 C CG2 . VAL B 1 148 ? -55.714 -38.564 65.976 1.00 59.89 ? 148 VAL B CG2 1 ATOM 5354 N N . GLY B 1 149 ? -58.798 -39.657 65.304 1.00 61.21 ? 149 GLY B N 1 ATOM 5355 C CA . GLY B 1 149 ? -59.322 -41.005 65.272 1.00 61.47 ? 149 GLY B CA 1 ATOM 5356 C C . GLY B 1 149 ? -60.489 -41.128 66.226 1.00 62.09 ? 149 GLY B C 1 ATOM 5357 O O . GLY B 1 149 ? -60.991 -40.133 66.765 1.00 62.05 ? 149 GLY B O 1 ATOM 5358 N N . ALA B 1 150 ? -60.927 -42.359 66.440 1.00 62.51 ? 150 ALA B N 1 ATOM 5359 C CA . ALA B 1 150 ? -62.077 -42.615 67.293 1.00 62.85 ? 150 ALA B CA 1 ATOM 5360 C C . ALA B 1 150 ? -62.076 -41.735 68.535 1.00 63.22 ? 150 ALA B C 1 ATOM 5361 O O . ALA B 1 150 ? -63.104 -41.198 68.931 1.00 63.38 ? 150 ALA B O 1 ATOM 5362 C CB . ALA B 1 150 ? -62.105 -44.072 67.693 1.00 62.71 ? 150 ALA B CB 1 ATOM 5363 N N . LEU B 1 151 ? -60.914 -41.597 69.161 1.00 63.89 ? 151 LEU B N 1 ATOM 5364 C CA . LEU B 1 151 ? -60.829 -40.877 70.422 1.00 64.55 ? 151 LEU B CA 1 ATOM 5365 C C . LEU B 1 151 ? -61.312 -39.441 70.288 1.00 65.23 ? 151 LEU B C 1 ATOM 5366 O O . LEU B 1 151 ? -61.693 -38.819 71.298 1.00 65.23 ? 151 LEU B O 1 ATOM 5367 C CB . LEU B 1 151 ? -59.395 -40.904 70.971 1.00 64.37 ? 151 LEU B CB 1 ATOM 5368 C CG . LEU B 1 151 ? -58.971 -42.232 71.602 1.00 63.86 ? 151 LEU B CG 1 ATOM 5369 C CD1 . LEU B 1 151 ? -57.515 -42.155 71.970 1.00 63.78 ? 151 LEU B CD1 1 ATOM 5370 C CD2 . LEU B 1 151 ? -59.828 -42.581 72.824 1.00 62.68 ? 151 LEU B CD2 1 ATOM 5371 N N . GLY B 1 152 ? -61.281 -38.920 69.051 1.00 65.87 ? 152 GLY B N 1 ATOM 5372 C CA . GLY B 1 152 ? -61.640 -37.521 68.778 1.00 66.44 ? 152 GLY B CA 1 ATOM 5373 C C . GLY B 1 152 ? -62.978 -37.353 68.083 1.00 66.91 ? 152 GLY B C 1 ATOM 5374 O O . GLY B 1 152 ? -63.614 -36.295 68.182 1.00 66.52 ? 152 GLY B O 1 ATOM 5375 N N . PHE B 1 153 ? -63.417 -38.419 67.412 1.00 67.43 ? 153 PHE B N 1 ATOM 5376 C CA . PHE B 1 153 ? -64.525 -38.324 66.488 1.00 67.92 ? 153 PHE B CA 1 ATOM 5377 C C . PHE B 1 153 ? -65.491 -39.470 66.556 1.00 69.12 ? 153 PHE B C 1 ATOM 5378 O O . PHE B 1 153 ? -66.320 -39.650 65.652 1.00 69.48 ? 153 PHE B O 1 ATOM 5379 C CB . PHE B 1 153 ? -63.965 -38.190 65.094 1.00 67.31 ? 153 PHE B CB 1 ATOM 5380 C CG . PHE B 1 153 ? -63.189 -36.953 64.929 1.00 65.73 ? 153 PHE B CG 1 ATOM 5381 C CD1 . PHE B 1 153 ? -63.819 -35.727 64.982 1.00 65.25 ? 153 PHE B CD1 1 ATOM 5382 C CD2 . PHE B 1 153 ? -61.838 -36.995 64.795 1.00 64.40 ? 153 PHE B CD2 1 ATOM 5383 C CE1 . PHE B 1 153 ? -63.115 -34.569 64.858 1.00 64.26 ? 153 PHE B CE1 1 ATOM 5384 C CE2 . PHE B 1 153 ? -61.131 -35.847 64.659 1.00 64.14 ? 153 PHE B CE2 1 ATOM 5385 C CZ . PHE B 1 153 ? -61.770 -34.627 64.700 1.00 63.78 ? 153 PHE B CZ 1 ATOM 5386 N N . LEU B 1 154 ? -65.382 -40.253 67.624 1.00 70.36 ? 154 LEU B N 1 ATOM 5387 C CA . LEU B 1 154 ? -66.283 -41.356 67.821 1.00 71.32 ? 154 LEU B CA 1 ATOM 5388 C C . LEU B 1 154 ? -67.609 -40.687 67.970 1.00 72.28 ? 154 LEU B C 1 ATOM 5389 O O . LEU B 1 154 ? -67.756 -39.740 68.726 1.00 72.01 ? 154 LEU B O 1 ATOM 5390 C CB . LEU B 1 154 ? -65.946 -42.138 69.082 1.00 71.36 ? 154 LEU B CB 1 ATOM 5391 C CG . LEU B 1 154 ? -66.953 -43.254 69.403 1.00 71.47 ? 154 LEU B CG 1 ATOM 5392 C CD1 . LEU B 1 154 ? -66.585 -44.559 68.707 1.00 71.80 ? 154 LEU B CD1 1 ATOM 5393 C CD2 . LEU B 1 154 ? -67.090 -43.476 70.899 1.00 69.71 ? 154 LEU B CD2 1 ATOM 5394 N N . ALA B 1 155 ? -68.578 -41.177 67.226 1.00 74.11 ? 155 ALA B N 1 ATOM 5395 C CA . ALA B 1 155 ? -69.855 -40.519 67.152 1.00 76.04 ? 155 ALA B CA 1 ATOM 5396 C C . ALA B 1 155 ? -70.985 -41.463 67.499 1.00 77.40 ? 155 ALA B C 1 ATOM 5397 O O . ALA B 1 155 ? -71.191 -42.484 66.842 1.00 77.65 ? 155 ALA B O 1 ATOM 5398 C CB . ALA B 1 155 ? -70.061 -39.935 65.754 1.00 75.95 ? 155 ALA B CB 1 ATOM 5399 N N . LEU B 1 156 ? -71.713 -41.112 68.545 1.00 79.19 ? 156 LEU B N 1 ATOM 5400 C CA . LEU B 1 156 ? -72.975 -41.756 68.833 1.00 81.11 ? 156 LEU B CA 1 ATOM 5401 C C . LEU B 1 156 ? -74.019 -40.649 68.870 1.00 82.33 ? 156 LEU B C 1 ATOM 5402 O O . LEU B 1 156 ? -74.223 -40.004 69.896 1.00 82.64 ? 156 LEU B O 1 ATOM 5403 C CB . LEU B 1 156 ? -72.899 -42.491 70.160 1.00 81.17 ? 156 LEU B CB 1 ATOM 5404 C CG . LEU B 1 156 ? -73.685 -43.796 70.198 1.00 81.67 ? 156 LEU B CG 1 ATOM 5405 C CD1 . LEU B 1 156 ? -73.241 -44.759 69.086 1.00 80.85 ? 156 LEU B CD1 1 ATOM 5406 C CD2 . LEU B 1 156 ? -73.524 -44.415 71.584 1.00 82.67 ? 156 LEU B CD2 1 ATOM 5407 N N . PRO B 1 157 ? -74.684 -40.429 67.731 1.00 83.46 ? 157 PRO B N 1 ATOM 5408 C CA . PRO B 1 157 ? -75.385 -39.180 67.431 1.00 83.98 ? 157 PRO B CA 1 ATOM 5409 C C . PRO B 1 157 ? -76.330 -38.727 68.535 1.00 84.29 ? 157 PRO B C 1 ATOM 5410 O O . PRO B 1 157 ? -77.282 -39.446 68.872 1.00 84.24 ? 157 PRO B O 1 ATOM 5411 C CB . PRO B 1 157 ? -76.180 -39.521 66.169 1.00 84.29 ? 157 PRO B CB 1 ATOM 5412 C CG . PRO B 1 157 ? -75.440 -40.696 65.551 1.00 84.21 ? 157 PRO B CG 1 ATOM 5413 C CD . PRO B 1 157 ? -74.935 -41.475 66.722 1.00 83.62 ? 157 PRO B CD 1 ATOM 5414 N N . GLY B 1 158 ? -76.059 -37.540 69.082 1.00 84.51 ? 158 GLY B N 1 ATOM 5415 C CA . GLY B 1 158 ? -76.954 -36.909 70.055 1.00 84.87 ? 158 GLY B CA 1 ATOM 5416 C C . GLY B 1 158 ? -76.776 -37.426 71.473 1.00 85.06 ? 158 GLY B C 1 ATOM 5417 O O . GLY B 1 158 ? -77.313 -36.859 72.432 1.00 85.17 ? 158 GLY B O 1 ATOM 5418 N N . ASN B 1 159 ? -76.020 -38.514 71.587 1.00 85.03 ? 159 ASN B N 1 ATOM 5419 C CA . ASN B 1 159 ? -75.632 -39.118 72.853 1.00 84.92 ? 159 ASN B CA 1 ATOM 5420 C C . ASN B 1 159 ? -74.434 -38.375 73.464 1.00 84.61 ? 159 ASN B C 1 ATOM 5421 O O . ASN B 1 159 ? -73.309 -38.538 72.990 1.00 84.70 ? 159 ASN B O 1 ATOM 5422 C CB . ASN B 1 159 ? -75.231 -40.553 72.548 1.00 85.07 ? 159 ASN B CB 1 ATOM 5423 C CG . ASN B 1 159 ? -75.375 -41.457 73.722 1.00 86.02 ? 159 ASN B CG 1 ATOM 5424 O OD1 . ASN B 1 159 ? -75.102 -41.072 74.866 1.00 86.83 ? 159 ASN B OD1 1 ATOM 5425 N ND2 . ASN B 1 159 ? -75.802 -42.688 73.455 1.00 86.52 ? 159 ASN B ND2 1 ATOM 5426 N N . PRO B 1 160 ? -74.664 -37.579 74.528 1.00 84.26 ? 160 PRO B N 1 ATOM 5427 C CA . PRO B 1 160 ? -73.642 -36.659 75.079 1.00 83.83 ? 160 PRO B CA 1 ATOM 5428 C C . PRO B 1 160 ? -72.386 -37.377 75.572 1.00 83.51 ? 160 PRO B C 1 ATOM 5429 O O . PRO B 1 160 ? -71.376 -36.736 75.875 1.00 83.33 ? 160 PRO B O 1 ATOM 5430 C CB . PRO B 1 160 ? -74.361 -35.976 76.250 1.00 83.60 ? 160 PRO B CB 1 ATOM 5431 C CG . PRO B 1 160 ? -75.822 -36.210 76.007 1.00 84.26 ? 160 PRO B CG 1 ATOM 5432 C CD . PRO B 1 160 ? -75.912 -37.545 75.306 1.00 84.24 ? 160 PRO B CD 1 ATOM 5433 N N . GLU B 1 161 ? -72.450 -38.704 75.635 1.00 83.15 ? 161 GLU B N 1 ATOM 5434 C CA . GLU B 1 161 ? -71.293 -39.513 76.023 1.00 82.96 ? 161 GLU B CA 1 ATOM 5435 C C . GLU B 1 161 ? -70.261 -39.635 74.908 1.00 81.74 ? 161 GLU B C 1 ATOM 5436 O O . GLU B 1 161 ? -69.050 -39.599 75.152 1.00 81.89 ? 161 GLU B O 1 ATOM 5437 C CB . GLU B 1 161 ? -71.744 -40.909 76.458 1.00 83.60 ? 161 GLU B CB 1 ATOM 5438 C CG . GLU B 1 161 ? -72.641 -40.900 77.698 1.00 86.56 ? 161 GLU B CG 1 ATOM 5439 C CD . GLU B 1 161 ? -71.956 -40.320 78.952 1.00 89.66 ? 161 GLU B CD 1 ATOM 5440 O OE1 . GLU B 1 161 ? -70.827 -39.753 78.860 1.00 90.12 ? 161 GLU B OE1 1 ATOM 5441 O OE2 . GLU B 1 161 ? -72.571 -40.434 80.038 1.00 91.15 ? 161 GLU B OE2 1 ATOM 5442 N N . ALA B 1 162 ? -70.766 -39.804 73.689 1.00 80.23 ? 162 ALA B N 1 ATOM 5443 C CA . ALA B 1 162 ? -69.967 -39.798 72.472 1.00 78.40 ? 162 ALA B CA 1 ATOM 5444 C C . ALA B 1 162 ? -70.767 -39.002 71.449 1.00 77.15 ? 162 ALA B C 1 ATOM 5445 O O . ALA B 1 162 ? -71.401 -39.561 70.553 1.00 77.08 ? 162 ALA B O 1 ATOM 5446 C CB . ALA B 1 162 ? -69.720 -41.212 71.986 1.00 78.31 ? 162 ALA B CB 1 ATOM 5447 N N . PRO B 1 163 ? -70.754 -37.673 71.596 1.00 75.75 ? 163 PRO B N 1 ATOM 5448 C CA . PRO B 1 163 ? -71.543 -36.818 70.735 1.00 74.71 ? 163 PRO B CA 1 ATOM 5449 C C . PRO B 1 163 ? -70.851 -36.502 69.404 1.00 73.60 ? 163 PRO B C 1 ATOM 5450 O O . PRO B 1 163 ? -71.407 -35.749 68.622 1.00 73.98 ? 163 PRO B O 1 ATOM 5451 C CB . PRO B 1 163 ? -71.663 -35.542 71.563 1.00 74.63 ? 163 PRO B CB 1 ATOM 5452 C CG . PRO B 1 163 ? -70.346 -35.463 72.247 1.00 74.94 ? 163 PRO B CG 1 ATOM 5453 C CD . PRO B 1 163 ? -69.963 -36.894 72.564 1.00 75.42 ? 163 PRO B CD 1 ATOM 5454 N N . GLY B 1 164 ? -69.659 -37.046 69.151 1.00 72.11 ? 164 GLY B N 1 ATOM 5455 C CA . GLY B 1 164 ? -68.949 -36.811 67.880 1.00 70.17 ? 164 GLY B CA 1 ATOM 5456 C C . GLY B 1 164 ? -68.267 -35.451 67.761 1.00 69.05 ? 164 GLY B C 1 ATOM 5457 O O . GLY B 1 164 ? -68.629 -34.505 68.479 1.00 69.07 ? 164 GLY B O 1 ATOM 5458 N N . ASN B 1 165 ? -67.277 -35.347 66.868 1.00 67.61 ? 165 ASN B N 1 ATOM 5459 C CA . ASN B 1 165 ? -66.610 -34.070 66.595 1.00 66.67 ? 165 ASN B CA 1 ATOM 5460 C C . ASN B 1 165 ? -65.872 -33.529 67.802 1.00 66.29 ? 165 ASN B C 1 ATOM 5461 O O . ASN B 1 165 ? -65.763 -32.308 67.975 1.00 66.63 ? 165 ASN B O 1 ATOM 5462 C CB . ASN B 1 165 ? -67.616 -32.985 66.185 1.00 66.54 ? 165 ASN B CB 1 ATOM 5463 C CG . ASN B 1 165 ? -68.351 -33.297 64.879 1.00 66.55 ? 165 ASN B CG 1 ATOM 5464 O OD1 . ASN B 1 165 ? -67.779 -33.835 63.917 1.00 65.93 ? 165 ASN B OD1 1 ATOM 5465 N ND2 . ASN B 1 165 ? -69.636 -32.939 64.840 1.00 66.77 ? 165 ASN B ND2 1 ATOM 5466 N N . MET B 1 166 ? -65.385 -34.418 68.661 1.00 65.38 ? 166 MET B N 1 ATOM 5467 C CA . MET B 1 166 ? -64.760 -33.963 69.889 1.00 64.24 ? 166 MET B CA 1 ATOM 5468 C C . MET B 1 166 ? -63.500 -33.178 69.561 1.00 63.87 ? 166 MET B C 1 ATOM 5469 O O . MET B 1 166 ? -63.273 -32.086 70.090 1.00 63.76 ? 166 MET B O 1 ATOM 5470 C CB . MET B 1 166 ? -64.451 -35.150 70.783 1.00 64.13 ? 166 MET B CB 1 ATOM 5471 C CG . MET B 1 166 ? -65.673 -35.713 71.485 1.00 63.37 ? 166 MET B CG 1 ATOM 5472 S SD . MET B 1 166 ? -66.665 -36.885 70.521 1.00 62.35 ? 166 MET B SD 1 ATOM 5473 C CE . MET B 1 166 ? -65.418 -38.098 70.063 1.00 61.33 ? 166 MET B CE 1 ATOM 5474 N N . GLY B 1 167 ? -62.693 -33.736 68.669 1.00 63.35 ? 167 GLY B N 1 ATOM 5475 C CA . GLY B 1 167 ? -61.494 -33.057 68.207 1.00 63.09 ? 167 GLY B CA 1 ATOM 5476 C C . GLY B 1 167 ? -61.793 -31.653 67.698 1.00 62.82 ? 167 GLY B C 1 ATOM 5477 O O . GLY B 1 167 ? -60.976 -30.720 67.861 1.00 62.68 ? 167 GLY B O 1 ATOM 5478 N N . LEU B 1 168 ? -62.962 -31.495 67.075 1.00 62.26 ? 168 LEU B N 1 ATOM 5479 C CA . LEU B 1 168 ? -63.304 -30.212 66.474 1.00 61.91 ? 168 LEU B CA 1 ATOM 5480 C C . LEU B 1 168 ? -63.527 -29.219 67.571 1.00 61.93 ? 168 LEU B C 1 ATOM 5481 O O . LEU B 1 168 ? -63.037 -28.079 67.517 1.00 61.96 ? 168 LEU B O 1 ATOM 5482 C CB . LEU B 1 168 ? -64.540 -30.318 65.595 1.00 61.75 ? 168 LEU B CB 1 ATOM 5483 C CG . LEU B 1 168 ? -64.150 -30.763 64.185 1.00 61.23 ? 168 LEU B CG 1 ATOM 5484 C CD1 . LEU B 1 168 ? -65.378 -30.946 63.326 1.00 60.51 ? 168 LEU B CD1 1 ATOM 5485 C CD2 . LEU B 1 168 ? -63.196 -29.721 63.605 1.00 60.37 ? 168 LEU B CD2 1 ATOM 5486 N N . PHE B 1 169 ? -64.249 -29.673 68.592 1.00 61.74 ? 169 PHE B N 1 ATOM 5487 C CA . PHE B 1 169 ? -64.467 -28.861 69.774 1.00 61.40 ? 169 PHE B CA 1 ATOM 5488 C C . PHE B 1 169 ? -63.169 -28.555 70.489 1.00 61.43 ? 169 PHE B C 1 ATOM 5489 O O . PHE B 1 169 ? -63.002 -27.452 71.008 1.00 61.62 ? 169 PHE B O 1 ATOM 5490 C CB . PHE B 1 169 ? -65.419 -29.551 70.702 1.00 61.47 ? 169 PHE B CB 1 ATOM 5491 C CG . PHE B 1 169 ? -66.844 -29.306 70.366 1.00 61.65 ? 169 PHE B CG 1 ATOM 5492 C CD1 . PHE B 1 169 ? -67.608 -30.298 69.764 1.00 60.46 ? 169 PHE B CD1 1 ATOM 5493 C CD2 . PHE B 1 169 ? -67.429 -28.073 70.661 1.00 61.50 ? 169 PHE B CD2 1 ATOM 5494 C CE1 . PHE B 1 169 ? -68.942 -30.063 69.467 1.00 61.46 ? 169 PHE B CE1 1 ATOM 5495 C CE2 . PHE B 1 169 ? -68.758 -27.835 70.364 1.00 61.26 ? 169 PHE B CE2 1 ATOM 5496 C CZ . PHE B 1 169 ? -69.515 -28.825 69.752 1.00 61.10 ? 169 PHE B CZ 1 ATOM 5497 N N . ASP B 1 170 ? -62.247 -29.516 70.511 1.00 61.27 ? 170 ASP B N 1 ATOM 5498 C CA . ASP B 1 170 ? -60.917 -29.232 71.014 1.00 61.38 ? 170 ASP B CA 1 ATOM 5499 C C . ASP B 1 170 ? -60.474 -27.942 70.323 1.00 61.46 ? 170 ASP B C 1 ATOM 5500 O O . ASP B 1 170 ? -60.312 -26.900 70.963 1.00 61.30 ? 170 ASP B O 1 ATOM 5501 C CB . ASP B 1 170 ? -59.947 -30.377 70.680 1.00 61.63 ? 170 ASP B CB 1 ATOM 5502 C CG . ASP B 1 170 ? -60.241 -31.663 71.467 1.00 62.22 ? 170 ASP B CG 1 ATOM 5503 O OD1 . ASP B 1 170 ? -60.888 -31.550 72.546 1.00 63.34 ? 170 ASP B OD1 1 ATOM 5504 O OD2 . ASP B 1 170 ? -59.806 -32.770 71.022 1.00 61.20 ? 170 ASP B OD2 1 ATOM 5505 N N . GLN B 1 171 ? -60.323 -28.019 69.002 1.00 61.41 ? 171 GLN B N 1 ATOM 5506 C CA . GLN B 1 171 ? -59.837 -26.902 68.210 1.00 61.38 ? 171 GLN B CA 1 ATOM 5507 C C . GLN B 1 171 ? -60.552 -25.627 68.610 1.00 61.34 ? 171 GLN B C 1 ATOM 5508 O O . GLN B 1 171 ? -59.929 -24.572 68.803 1.00 61.30 ? 171 GLN B O 1 ATOM 5509 C CB . GLN B 1 171 ? -60.080 -27.172 66.723 1.00 61.60 ? 171 GLN B CB 1 ATOM 5510 C CG . GLN B 1 171 ? -59.518 -28.496 66.208 1.00 62.14 ? 171 GLN B CG 1 ATOM 5511 C CD . GLN B 1 171 ? -59.626 -28.645 64.689 1.00 62.48 ? 171 GLN B CD 1 ATOM 5512 O OE1 . GLN B 1 171 ? -59.830 -27.663 63.957 1.00 64.21 ? 171 GLN B OE1 1 ATOM 5513 N NE2 . GLN B 1 171 ? -59.481 -29.880 64.209 1.00 61.28 ? 171 GLN B NE2 1 ATOM 5514 N N . GLN B 1 172 ? -61.870 -25.722 68.723 1.00 61.10 ? 172 GLN B N 1 ATOM 5515 C CA . GLN B 1 172 ? -62.655 -24.559 69.103 1.00 61.36 ? 172 GLN B CA 1 ATOM 5516 C C . GLN B 1 172 ? -62.299 -24.006 70.483 1.00 61.55 ? 172 GLN B C 1 ATOM 5517 O O . GLN B 1 172 ? -62.267 -22.788 70.699 1.00 61.10 ? 172 GLN B O 1 ATOM 5518 C CB . GLN B 1 172 ? -64.127 -24.897 69.086 1.00 61.41 ? 172 GLN B CB 1 ATOM 5519 C CG . GLN B 1 172 ? -65.001 -23.700 69.358 1.00 61.04 ? 172 GLN B CG 1 ATOM 5520 C CD . GLN B 1 172 ? -66.446 -24.005 69.039 1.00 61.66 ? 172 GLN B CD 1 ATOM 5521 O OE1 . GLN B 1 172 ? -66.909 -23.802 67.906 1.00 60.82 ? 172 GLN B OE1 1 ATOM 5522 N NE2 . GLN B 1 172 ? -67.166 -24.538 70.031 1.00 62.52 ? 172 GLN B NE2 1 ATOM 5523 N N . LEU B 1 173 ? -62.048 -24.904 71.425 1.00 61.82 ? 173 LEU B N 1 ATOM 5524 C CA . LEU B 1 173 ? -61.623 -24.451 72.730 1.00 62.55 ? 173 LEU B CA 1 ATOM 5525 C C . LEU B 1 173 ? -60.258 -23.763 72.618 1.00 62.80 ? 173 LEU B C 1 ATOM 5526 O O . LEU B 1 173 ? -59.996 -22.763 73.294 1.00 63.18 ? 173 LEU B O 1 ATOM 5527 C CB . LEU B 1 173 ? -61.599 -25.594 73.753 1.00 62.68 ? 173 LEU B CB 1 ATOM 5528 C CG . LEU B 1 173 ? -61.554 -25.163 75.230 1.00 62.58 ? 173 LEU B CG 1 ATOM 5529 C CD1 . LEU B 1 173 ? -62.398 -23.893 75.455 1.00 62.35 ? 173 LEU B CD1 1 ATOM 5530 C CD2 . LEU B 1 173 ? -61.988 -26.301 76.163 1.00 61.79 ? 173 LEU B CD2 1 ATOM 5531 N N . ALA B 1 174 ? -59.398 -24.269 71.748 1.00 62.86 ? 174 ALA B N 1 ATOM 5532 C CA . ALA B 1 174 ? -58.122 -23.612 71.546 1.00 63.29 ? 174 ALA B CA 1 ATOM 5533 C C . ALA B 1 174 ? -58.354 -22.191 71.018 1.00 63.90 ? 174 ALA B C 1 ATOM 5534 O O . ALA B 1 174 ? -57.613 -21.247 71.353 1.00 64.00 ? 174 ALA B O 1 ATOM 5535 C CB . ALA B 1 174 ? -57.239 -24.416 70.603 1.00 63.02 ? 174 ALA B CB 1 ATOM 5536 N N . LEU B 1 175 ? -59.391 -22.027 70.202 1.00 64.30 ? 175 LEU B N 1 ATOM 5537 C CA . LEU B 1 175 ? -59.675 -20.697 69.681 1.00 64.91 ? 175 LEU B CA 1 ATOM 5538 C C . LEU B 1 175 ? -60.116 -19.794 70.819 1.00 65.23 ? 175 LEU B C 1 ATOM 5539 O O . LEU B 1 175 ? -59.597 -18.694 70.959 1.00 65.09 ? 175 LEU B O 1 ATOM 5540 C CB . LEU B 1 175 ? -60.731 -20.736 68.574 1.00 64.89 ? 175 LEU B CB 1 ATOM 5541 C CG . LEU B 1 175 ? -60.360 -21.696 67.449 1.00 64.63 ? 175 LEU B CG 1 ATOM 5542 C CD1 . LEU B 1 175 ? -61.345 -21.542 66.305 1.00 64.23 ? 175 LEU B CD1 1 ATOM 5543 C CD2 . LEU B 1 175 ? -58.934 -21.431 66.992 1.00 63.63 ? 175 LEU B CD2 1 ATOM 5544 N N . GLN B 1 176 ? -61.064 -20.267 71.628 1.00 65.99 ? 176 GLN B N 1 ATOM 5545 C CA . GLN B 1 176 ? -61.534 -19.508 72.795 1.00 67.12 ? 176 GLN B CA 1 ATOM 5546 C C . GLN B 1 176 ? -60.373 -19.118 73.667 1.00 66.77 ? 176 GLN B C 1 ATOM 5547 O O . GLN B 1 176 ? -60.343 -18.026 74.236 1.00 66.59 ? 176 GLN B O 1 ATOM 5548 C CB . GLN B 1 176 ? -62.478 -20.334 73.652 1.00 67.53 ? 176 GLN B CB 1 ATOM 5549 C CG . GLN B 1 176 ? -63.922 -19.863 73.657 1.00 71.03 ? 176 GLN B CG 1 ATOM 5550 C CD . GLN B 1 176 ? -64.886 -21.016 74.031 1.00 76.24 ? 176 GLN B CD 1 ATOM 5551 O OE1 . GLN B 1 176 ? -65.136 -21.928 73.224 1.00 77.98 ? 176 GLN B OE1 1 ATOM 5552 N NE2 . GLN B 1 176 ? -65.413 -20.983 75.264 1.00 77.57 ? 176 GLN B NE2 1 ATOM 5553 N N . TRP B 1 177 ? -59.428 -20.038 73.796 1.00 66.61 ? 177 TRP B N 1 ATOM 5554 C CA . TRP B 1 177 ? -58.271 -19.754 74.588 1.00 66.75 ? 177 TRP B CA 1 ATOM 5555 C C . TRP B 1 177 ? -57.583 -18.520 74.030 1.00 66.66 ? 177 TRP B C 1 ATOM 5556 O O . TRP B 1 177 ? -57.394 -17.535 74.749 1.00 66.99 ? 177 TRP B O 1 ATOM 5557 C CB . TRP B 1 177 ? -57.302 -20.920 74.611 1.00 66.88 ? 177 TRP B CB 1 ATOM 5558 C CG . TRP B 1 177 ? -56.217 -20.676 75.608 1.00 67.63 ? 177 TRP B CG 1 ATOM 5559 C CD1 . TRP B 1 177 ? -56.252 -20.974 76.942 1.00 67.38 ? 177 TRP B CD1 1 ATOM 5560 C CD2 . TRP B 1 177 ? -54.946 -20.053 75.368 1.00 68.15 ? 177 TRP B CD2 1 ATOM 5561 N NE1 . TRP B 1 177 ? -55.080 -20.593 77.541 1.00 67.64 ? 177 TRP B NE1 1 ATOM 5562 C CE2 . TRP B 1 177 ? -54.259 -20.024 76.600 1.00 67.92 ? 177 TRP B CE2 1 ATOM 5563 C CE3 . TRP B 1 177 ? -54.319 -19.532 74.232 1.00 69.02 ? 177 TRP B CE3 1 ATOM 5564 C CZ2 . TRP B 1 177 ? -52.973 -19.481 76.733 1.00 68.37 ? 177 TRP B CZ2 1 ATOM 5565 C CZ3 . TRP B 1 177 ? -53.041 -19.001 74.359 1.00 69.49 ? 177 TRP B CZ3 1 ATOM 5566 C CH2 . TRP B 1 177 ? -52.382 -18.977 75.604 1.00 69.45 ? 177 TRP B CH2 1 ATOM 5567 N N . VAL B 1 178 ? -57.220 -18.555 72.747 1.00 66.35 ? 178 VAL B N 1 ATOM 5568 C CA . VAL B 1 178 ? -56.533 -17.411 72.157 1.00 65.69 ? 178 VAL B CA 1 ATOM 5569 C C . VAL B 1 178 ? -57.384 -16.174 72.391 1.00 65.87 ? 178 VAL B C 1 ATOM 5570 O O . VAL B 1 178 ? -56.874 -15.075 72.660 1.00 65.66 ? 178 VAL B O 1 ATOM 5571 C CB . VAL B 1 178 ? -56.267 -17.598 70.674 1.00 65.21 ? 178 VAL B CB 1 ATOM 5572 C CG1 . VAL B 1 178 ? -55.487 -16.422 70.171 1.00 64.58 ? 178 VAL B CG1 1 ATOM 5573 C CG2 . VAL B 1 178 ? -55.489 -18.884 70.430 1.00 64.75 ? 178 VAL B CG2 1 ATOM 5574 N N . GLN B 1 179 ? -58.694 -16.382 72.339 1.00 66.05 ? 179 GLN B N 1 ATOM 5575 C CA . GLN B 1 179 ? -59.614 -15.284 72.460 1.00 66.77 ? 179 GLN B CA 1 ATOM 5576 C C . GLN B 1 179 ? -59.442 -14.598 73.790 1.00 67.63 ? 179 GLN B C 1 ATOM 5577 O O . GLN B 1 179 ? -59.413 -13.360 73.865 1.00 67.53 ? 179 GLN B O 1 ATOM 5578 C CB . GLN B 1 179 ? -61.063 -15.733 72.252 1.00 66.53 ? 179 GLN B CB 1 ATOM 5579 C CG . GLN B 1 179 ? -61.488 -15.612 70.803 1.00 66.16 ? 179 GLN B CG 1 ATOM 5580 C CD . GLN B 1 179 ? -61.033 -14.282 70.195 1.00 65.37 ? 179 GLN B CD 1 ATOM 5581 O OE1 . GLN B 1 179 ? -61.654 -13.239 70.436 1.00 65.59 ? 179 GLN B OE1 1 ATOM 5582 N NE2 . GLN B 1 179 ? -59.938 -14.310 69.419 1.00 63.95 ? 179 GLN B NE2 1 ATOM 5583 N N . LYS B 1 180 ? -59.301 -15.407 74.839 1.00 68.62 ? 180 LYS B N 1 ATOM 5584 C CA . LYS B 1 180 ? -59.295 -14.884 76.194 1.00 69.06 ? 180 LYS B CA 1 ATOM 5585 C C . LYS B 1 180 ? -57.917 -14.462 76.627 1.00 69.17 ? 180 LYS B C 1 ATOM 5586 O O . LYS B 1 180 ? -57.793 -13.639 77.523 1.00 69.77 ? 180 LYS B O 1 ATOM 5587 C CB . LYS B 1 180 ? -59.882 -15.901 77.155 1.00 69.16 ? 180 LYS B CB 1 ATOM 5588 C CG . LYS B 1 180 ? -61.413 -15.880 77.177 1.00 70.98 ? 180 LYS B CG 1 ATOM 5589 C CD . LYS B 1 180 ? -62.009 -16.923 78.156 1.00 74.19 ? 180 LYS B CD 1 ATOM 5590 C CE . LYS B 1 180 ? -63.399 -16.491 78.696 1.00 76.33 ? 180 LYS B CE 1 ATOM 5591 N NZ . LYS B 1 180 ? -64.159 -17.592 79.402 1.00 76.99 ? 180 LYS B NZ 1 ATOM 5592 N N . ASN B 1 181 ? -56.884 -14.967 75.962 1.00 69.21 ? 181 ASN B N 1 ATOM 5593 C CA . ASN B 1 181 ? -55.534 -14.803 76.494 1.00 69.57 ? 181 ASN B CA 1 ATOM 5594 C C . ASN B 1 181 ? -54.513 -14.101 75.623 1.00 69.49 ? 181 ASN B C 1 ATOM 5595 O O . ASN B 1 181 ? -53.573 -13.489 76.163 1.00 70.01 ? 181 ASN B O 1 ATOM 5596 C CB . ASN B 1 181 ? -54.954 -16.157 76.910 1.00 69.82 ? 181 ASN B CB 1 ATOM 5597 C CG . ASN B 1 181 ? -55.758 -16.805 78.008 1.00 71.23 ? 181 ASN B CG 1 ATOM 5598 O OD1 . ASN B 1 181 ? -55.916 -16.225 79.082 1.00 72.75 ? 181 ASN B OD1 1 ATOM 5599 N ND2 . ASN B 1 181 ? -56.305 -18.000 77.741 1.00 72.80 ? 181 ASN B ND2 1 ATOM 5600 N N . ILE B 1 182 ? -54.657 -14.192 74.299 1.00 68.72 ? 182 ILE B N 1 ATOM 5601 C CA . ILE B 1 182 ? -53.545 -13.814 73.424 1.00 67.81 ? 182 ILE B CA 1 ATOM 5602 C C . ILE B 1 182 ? -53.131 -12.361 73.633 1.00 67.59 ? 182 ILE B C 1 ATOM 5603 O O . ILE B 1 182 ? -51.955 -12.011 73.476 1.00 67.48 ? 182 ILE B O 1 ATOM 5604 C CB . ILE B 1 182 ? -53.848 -14.105 71.936 1.00 67.73 ? 182 ILE B CB 1 ATOM 5605 C CG1 . ILE B 1 182 ? -52.549 -14.254 71.131 1.00 66.94 ? 182 ILE B CG1 1 ATOM 5606 C CG2 . ILE B 1 182 ? -54.725 -13.019 71.351 1.00 67.67 ? 182 ILE B CG2 1 ATOM 5607 C CD1 . ILE B 1 182 ? -51.770 -15.522 71.422 1.00 65.52 ? 182 ILE B CD1 1 ATOM 5608 N N . ALA B 1 183 ? -54.097 -11.524 74.009 1.00 67.36 ? 183 ALA B N 1 ATOM 5609 C CA . ALA B 1 183 ? -53.799 -10.135 74.319 1.00 67.35 ? 183 ALA B CA 1 ATOM 5610 C C . ALA B 1 183 ? -52.605 -10.012 75.294 1.00 67.52 ? 183 ALA B C 1 ATOM 5611 O O . ALA B 1 183 ? -51.664 -9.276 75.015 1.00 67.67 ? 183 ALA B O 1 ATOM 5612 C CB . ALA B 1 183 ? -55.038 -9.419 74.829 1.00 66.96 ? 183 ALA B CB 1 ATOM 5613 N N . ALA B 1 184 ? -52.618 -10.761 76.403 1.00 67.64 ? 184 ALA B N 1 ATOM 5614 C CA . ALA B 1 184 ? -51.465 -10.846 77.339 1.00 67.55 ? 184 ALA B CA 1 ATOM 5615 C C . ALA B 1 184 ? -50.079 -11.090 76.690 1.00 67.61 ? 184 ALA B C 1 ATOM 5616 O O . ALA B 1 184 ? -49.046 -10.718 77.267 1.00 67.80 ? 184 ALA B O 1 ATOM 5617 C CB . ALA B 1 184 ? -51.726 -11.896 78.420 1.00 67.37 ? 184 ALA B CB 1 ATOM 5618 N N . PHE B 1 185 ? -50.052 -11.727 75.518 1.00 67.43 ? 185 PHE B N 1 ATOM 5619 C CA . PHE B 1 185 ? -48.811 -11.861 74.756 1.00 67.05 ? 185 PHE B CA 1 ATOM 5620 C C . PHE B 1 185 ? -48.727 -10.786 73.681 1.00 67.08 ? 185 PHE B C 1 ATOM 5621 O O . PHE B 1 185 ? -47.821 -10.808 72.835 1.00 67.50 ? 185 PHE B O 1 ATOM 5622 C CB . PHE B 1 185 ? -48.710 -13.221 74.085 1.00 66.78 ? 185 PHE B CB 1 ATOM 5623 C CG . PHE B 1 185 ? -48.850 -14.373 75.024 1.00 66.61 ? 185 PHE B CG 1 ATOM 5624 C CD1 . PHE B 1 185 ? -50.049 -14.590 75.702 1.00 66.83 ? 185 PHE B CD1 1 ATOM 5625 C CD2 . PHE B 1 185 ? -47.792 -15.273 75.206 1.00 66.46 ? 185 PHE B CD2 1 ATOM 5626 C CE1 . PHE B 1 185 ? -50.193 -15.676 76.570 1.00 67.43 ? 185 PHE B CE1 1 ATOM 5627 C CE2 . PHE B 1 185 ? -47.917 -16.366 76.074 1.00 66.56 ? 185 PHE B CE2 1 ATOM 5628 C CZ . PHE B 1 185 ? -49.118 -16.566 76.763 1.00 67.36 ? 185 PHE B CZ 1 ATOM 5629 N N . GLY B 1 186 ? -49.666 -9.844 73.710 1.00 66.64 ? 186 GLY B N 1 ATOM 5630 C CA . GLY B 1 186 ? -49.659 -8.738 72.761 1.00 66.51 ? 186 GLY B CA 1 ATOM 5631 C C . GLY B 1 186 ? -50.315 -9.192 71.475 1.00 66.42 ? 186 GLY B C 1 ATOM 5632 O O . GLY B 1 186 ? -50.165 -8.565 70.431 1.00 66.45 ? 186 GLY B O 1 ATOM 5633 N N . GLY B 1 187 ? -51.037 -10.302 71.535 1.00 66.10 ? 187 GLY B N 1 ATOM 5634 C CA . GLY B 1 187 ? -51.801 -10.712 70.380 1.00 65.92 ? 187 GLY B CA 1 ATOM 5635 C C . GLY B 1 187 ? -53.017 -9.809 70.280 1.00 65.99 ? 187 GLY B C 1 ATOM 5636 O O . GLY B 1 187 ? -53.513 -9.328 71.307 1.00 65.94 ? 187 GLY B O 1 ATOM 5637 N N . ASN B 1 188 ? -53.469 -9.535 69.049 1.00 65.87 ? 188 ASN B N 1 ATOM 5638 C CA . ASN B 1 188 ? -54.774 -8.904 68.843 1.00 65.49 ? 188 ASN B CA 1 ATOM 5639 C C . ASN B 1 188 ? -55.887 -9.911 68.530 1.00 65.42 ? 188 ASN B C 1 ATOM 5640 O O . ASN B 1 188 ? -56.003 -10.396 67.400 1.00 65.50 ? 188 ASN B O 1 ATOM 5641 C CB . ASN B 1 188 ? -54.724 -7.852 67.750 1.00 65.31 ? 188 ASN B CB 1 ATOM 5642 C CG . ASN B 1 188 ? -56.099 -7.281 67.463 1.00 65.63 ? 188 ASN B CG 1 ATOM 5643 O OD1 . ASN B 1 188 ? -57.076 -7.616 68.137 1.00 65.05 ? 188 ASN B OD1 1 ATOM 5644 N ND2 . ASN B 1 188 ? -56.184 -6.416 66.469 1.00 66.96 ? 188 ASN B ND2 1 ATOM 5645 N N . PRO B 1 189 ? -56.717 -10.221 69.532 1.00 65.30 ? 189 PRO B N 1 ATOM 5646 C CA . PRO B 1 189 ? -57.788 -11.194 69.350 1.00 65.44 ? 189 PRO B CA 1 ATOM 5647 C C . PRO B 1 189 ? -58.724 -10.810 68.206 1.00 65.65 ? 189 PRO B C 1 ATOM 5648 O O . PRO B 1 189 ? -59.383 -11.668 67.652 1.00 65.83 ? 189 PRO B O 1 ATOM 5649 C CB . PRO B 1 189 ? -58.547 -11.120 70.672 1.00 65.30 ? 189 PRO B CB 1 ATOM 5650 C CG . PRO B 1 189 ? -58.238 -9.757 71.197 1.00 64.81 ? 189 PRO B CG 1 ATOM 5651 C CD . PRO B 1 189 ? -56.821 -9.523 70.820 1.00 65.07 ? 189 PRO B CD 1 ATOM 5652 N N . LYS B 1 190 ? -58.785 -9.528 67.864 1.00 65.70 ? 190 LYS B N 1 ATOM 5653 C CA . LYS B 1 190 ? -59.639 -9.070 66.763 1.00 65.89 ? 190 LYS B CA 1 ATOM 5654 C C . LYS B 1 190 ? -59.113 -9.393 65.348 1.00 65.42 ? 190 LYS B C 1 ATOM 5655 O O . LYS B 1 190 ? -59.881 -9.318 64.377 1.00 65.58 ? 190 LYS B O 1 ATOM 5656 C CB . LYS B 1 190 ? -59.890 -7.559 66.852 1.00 66.42 ? 190 LYS B CB 1 ATOM 5657 C CG . LYS B 1 190 ? -61.136 -7.163 67.633 1.00 68.78 ? 190 LYS B CG 1 ATOM 5658 C CD . LYS B 1 190 ? -60.804 -6.921 69.109 1.00 73.87 ? 190 LYS B CD 1 ATOM 5659 C CE . LYS B 1 190 ? -62.053 -6.624 69.930 1.00 75.40 ? 190 LYS B CE 1 ATOM 5660 N NZ . LYS B 1 190 ? -62.621 -5.311 69.505 1.00 77.82 ? 190 LYS B NZ 1 ATOM 5661 N N . SER B 1 191 ? -57.825 -9.721 65.221 1.00 64.26 ? 191 SER B N 1 ATOM 5662 C CA . SER B 1 191 ? -57.274 -10.028 63.922 1.00 63.16 ? 191 SER B CA 1 ATOM 5663 C C . SER B 1 191 ? -56.668 -11.411 63.884 1.00 62.54 ? 191 SER B C 1 ATOM 5664 O O . SER B 1 191 ? -55.443 -11.568 63.909 1.00 62.58 ? 191 SER B O 1 ATOM 5665 C CB . SER B 1 191 ? -56.223 -9.013 63.540 1.00 63.22 ? 191 SER B CB 1 ATOM 5666 O OG . SER B 1 191 ? -55.544 -9.473 62.384 1.00 63.87 ? 191 SER B OG 1 ATOM 5667 N N . VAL B 1 192 ? -57.529 -12.418 63.812 1.00 61.67 ? 192 VAL B N 1 ATOM 5668 C CA . VAL B 1 192 ? -57.078 -13.800 63.922 1.00 61.00 ? 192 VAL B CA 1 ATOM 5669 C C . VAL B 1 192 ? -57.358 -14.584 62.652 1.00 60.39 ? 192 VAL B C 1 ATOM 5670 O O . VAL B 1 192 ? -58.488 -14.641 62.179 1.00 60.45 ? 192 VAL B O 1 ATOM 5671 C CB . VAL B 1 192 ? -57.758 -14.524 65.114 1.00 60.98 ? 192 VAL B CB 1 ATOM 5672 C CG1 . VAL B 1 192 ? -57.512 -16.019 65.039 1.00 61.34 ? 192 VAL B CG1 1 ATOM 5673 C CG2 . VAL B 1 192 ? -57.251 -13.988 66.426 1.00 60.74 ? 192 VAL B CG2 1 ATOM 5674 N N . THR B 1 193 ? -56.325 -15.208 62.110 1.00 59.59 ? 193 THR B N 1 ATOM 5675 C CA . THR B 1 193 ? -56.490 -16.009 60.912 1.00 58.67 ? 193 THR B CA 1 ATOM 5676 C C . THR B 1 193 ? -56.240 -17.479 61.191 1.00 58.23 ? 193 THR B C 1 ATOM 5677 O O . THR B 1 193 ? -55.180 -17.846 61.698 1.00 58.72 ? 193 THR B O 1 ATOM 5678 C CB . THR B 1 193 ? -55.516 -15.590 59.845 1.00 58.35 ? 193 THR B CB 1 ATOM 5679 O OG1 . THR B 1 193 ? -55.773 -14.221 59.498 1.00 58.89 ? 193 THR B OG1 1 ATOM 5680 C CG2 . THR B 1 193 ? -55.699 -16.485 58.639 1.00 58.21 ? 193 THR B CG2 1 ATOM 5681 N N . LEU B 1 194 ? -57.207 -18.323 60.865 1.00 57.13 ? 194 LEU B N 1 ATOM 5682 C CA . LEU B 1 194 ? -56.986 -19.740 60.956 1.00 56.22 ? 194 LEU B CA 1 ATOM 5683 C C . LEU B 1 194 ? -56.327 -20.164 59.680 1.00 56.32 ? 194 LEU B C 1 ATOM 5684 O O . LEU B 1 194 ? -56.662 -19.645 58.628 1.00 56.68 ? 194 LEU B O 1 ATOM 5685 C CB . LEU B 1 194 ? -58.311 -20.470 61.078 1.00 55.68 ? 194 LEU B CB 1 ATOM 5686 C CG . LEU B 1 194 ? -59.212 -20.002 62.216 1.00 55.09 ? 194 LEU B CG 1 ATOM 5687 C CD1 . LEU B 1 194 ? -60.464 -20.862 62.277 1.00 54.19 ? 194 LEU B CD1 1 ATOM 5688 C CD2 . LEU B 1 194 ? -58.485 -19.998 63.579 1.00 54.59 ? 194 LEU B CD2 1 ATOM 5689 N N . PHE B 1 195 ? -55.383 -21.091 59.765 1.00 56.12 ? 195 PHE B N 1 ATOM 5690 C CA . PHE B 1 195 ? -54.897 -21.771 58.568 1.00 55.99 ? 195 PHE B CA 1 ATOM 5691 C C . PHE B 1 195 ? -54.498 -23.217 58.890 1.00 56.12 ? 195 PHE B C 1 ATOM 5692 O O . PHE B 1 195 ? -54.067 -23.534 60.016 1.00 56.45 ? 195 PHE B O 1 ATOM 5693 C CB . PHE B 1 195 ? -53.770 -20.997 57.881 1.00 55.71 ? 195 PHE B CB 1 ATOM 5694 C CG . PHE B 1 195 ? -52.457 -21.016 58.627 1.00 55.96 ? 195 PHE B CG 1 ATOM 5695 C CD1 . PHE B 1 195 ? -52.411 -20.793 60.000 1.00 55.21 ? 195 PHE B CD1 1 ATOM 5696 C CD2 . PHE B 1 195 ? -51.250 -21.195 57.936 1.00 55.78 ? 195 PHE B CD2 1 ATOM 5697 C CE1 . PHE B 1 195 ? -51.199 -20.795 60.684 1.00 54.84 ? 195 PHE B CE1 1 ATOM 5698 C CE2 . PHE B 1 195 ? -50.028 -21.188 58.610 1.00 54.56 ? 195 PHE B CE2 1 ATOM 5699 C CZ . PHE B 1 195 ? -50.009 -21.000 59.986 1.00 54.36 ? 195 PHE B CZ 1 ATOM 5700 N N . GLY B 1 196 ? -54.692 -24.095 57.908 1.00 55.63 ? 196 GLY B N 1 ATOM 5701 C CA . GLY B 1 196 ? -54.516 -25.527 58.097 1.00 54.85 ? 196 GLY B CA 1 ATOM 5702 C C . GLY B 1 196 ? -54.220 -26.177 56.767 1.00 54.49 ? 196 GLY B C 1 ATOM 5703 O O . GLY B 1 196 ? -54.040 -25.499 55.756 1.00 54.68 ? 196 GLY B O 1 ATOM 5704 N N . GLU B 1 197 ? -54.160 -27.496 56.758 1.00 54.06 ? 197 GLU B N 1 ATOM 5705 C CA . GLU B 1 197 ? -53.825 -28.203 55.552 1.00 53.82 ? 197 GLU B CA 1 ATOM 5706 C C . GLU B 1 197 ? -54.474 -29.552 55.659 1.00 53.72 ? 197 GLU B C 1 ATOM 5707 O O . GLU B 1 197 ? -54.735 -30.020 56.759 1.00 53.73 ? 197 GLU B O 1 ATOM 5708 C CB . GLU B 1 197 ? -52.316 -28.335 55.425 1.00 53.81 ? 197 GLU B CB 1 ATOM 5709 C CG . GLU B 1 197 ? -51.846 -28.786 54.052 1.00 55.13 ? 197 GLU B CG 1 ATOM 5710 C CD . GLU B 1 197 ? -51.680 -30.288 53.959 1.00 56.08 ? 197 GLU B CD 1 ATOM 5711 O OE1 . GLU B 1 197 ? -51.890 -30.972 54.998 1.00 53.96 ? 197 GLU B OE1 1 ATOM 5712 O OE2 . GLU B 1 197 ? -51.318 -30.763 52.845 1.00 57.62 ? 197 GLU B OE2 1 ATOM 5713 N N . SER B 1 198 ? -54.755 -30.164 54.515 1.00 53.81 ? 198 SER B N 1 ATOM 5714 C CA . SER B 1 198 ? -55.487 -31.429 54.456 1.00 53.56 ? 198 SER B CA 1 ATOM 5715 C C . SER B 1 198 ? -56.612 -31.405 55.487 1.00 53.30 ? 198 SER B C 1 ATOM 5716 O O . SER B 1 198 ? -57.416 -30.483 55.462 1.00 53.23 ? 198 SER B O 1 ATOM 5717 C CB . SER B 1 198 ? -54.521 -32.599 54.623 1.00 53.86 ? 198 SER B CB 1 ATOM 5718 O OG . SER B 1 198 ? -54.937 -33.754 53.925 1.00 54.12 ? 198 SER B OG 1 ATOM 5719 N N . ALA B 1 199 ? -56.688 -32.371 56.401 1.00 53.31 ? 199 ALA B N 1 ATOM 5720 C CA . ALA B 1 199 ? -57.789 -32.330 57.383 1.00 53.36 ? 199 ALA B CA 1 ATOM 5721 C C . ALA B 1 199 ? -57.764 -31.026 58.210 1.00 53.51 ? 199 ALA B C 1 ATOM 5722 O O . ALA B 1 199 ? -58.773 -30.606 58.772 1.00 52.76 ? 199 ALA B O 1 ATOM 5723 C CB . ALA B 1 199 ? -57.776 -33.554 58.282 1.00 53.12 ? 199 ALA B CB 1 ATOM 5724 N N . GLY B 1 200 ? -56.595 -30.388 58.277 1.00 54.14 ? 200 GLY B N 1 ATOM 5725 C CA . GLY B 1 200 ? -56.463 -29.083 58.928 1.00 54.72 ? 200 GLY B CA 1 ATOM 5726 C C . GLY B 1 200 ? -57.306 -28.059 58.187 1.00 55.52 ? 200 GLY B C 1 ATOM 5727 O O . GLY B 1 200 ? -58.154 -27.369 58.788 1.00 55.45 ? 200 GLY B O 1 ATOM 5728 N N . ALA B 1 201 ? -57.079 -27.972 56.871 1.00 56.02 ? 201 ALA B N 1 ATOM 5729 C CA . ALA B 1 201 ? -57.884 -27.117 56.007 1.00 56.27 ? 201 ALA B CA 1 ATOM 5730 C C . ALA B 1 201 ? -59.356 -27.437 56.217 1.00 56.44 ? 201 ALA B C 1 ATOM 5731 O O . ALA B 1 201 ? -60.157 -26.545 56.492 1.00 56.76 ? 201 ALA B O 1 ATOM 5732 C CB . ALA B 1 201 ? -57.489 -27.302 54.547 1.00 56.11 ? 201 ALA B CB 1 ATOM 5733 N N . ALA B 1 202 ? -59.708 -28.712 56.118 1.00 56.62 ? 202 ALA B N 1 ATOM 5734 C CA . ALA B 1 202 ? -61.118 -29.097 56.201 1.00 57.12 ? 202 ALA B CA 1 ATOM 5735 C C . ALA B 1 202 ? -61.721 -28.594 57.517 1.00 57.40 ? 202 ALA B C 1 ATOM 5736 O O . ALA B 1 202 ? -62.900 -28.246 57.600 1.00 57.43 ? 202 ALA B O 1 ATOM 5737 C CB . ALA B 1 202 ? -61.279 -30.607 56.054 1.00 56.74 ? 202 ALA B CB 1 ATOM 5738 N N . SER B 1 203 ? -60.892 -28.542 58.547 1.00 58.04 ? 203 SER B N 1 ATOM 5739 C CA . SER B 1 203 ? -61.358 -28.105 59.854 1.00 58.49 ? 203 SER B CA 1 ATOM 5740 C C . SER B 1 203 ? -61.607 -26.610 59.778 1.00 58.63 ? 203 SER B C 1 ATOM 5741 O O . SER B 1 203 ? -62.662 -26.115 60.177 1.00 58.51 ? 203 SER B O 1 ATOM 5742 C CB . SER B 1 203 ? -60.318 -28.434 60.933 1.00 58.34 ? 203 SER B CB 1 ATOM 5743 O OG . SER B 1 203 ? -59.912 -29.781 60.810 1.00 58.88 ? 203 SER B OG 1 ATOM 5744 N N . VAL B 1 204 ? -60.616 -25.897 59.255 1.00 58.92 ? 204 VAL B N 1 ATOM 5745 C CA . VAL B 1 204 ? -60.763 -24.475 59.026 1.00 59.30 ? 204 VAL B CA 1 ATOM 5746 C C . VAL B 1 204 ? -62.124 -24.210 58.369 1.00 59.32 ? 204 VAL B C 1 ATOM 5747 O O . VAL B 1 204 ? -62.914 -23.377 58.838 1.00 59.59 ? 204 VAL B O 1 ATOM 5748 C CB . VAL B 1 204 ? -59.655 -23.947 58.095 1.00 59.46 ? 204 VAL B CB 1 ATOM 5749 C CG1 . VAL B 1 204 ? -59.998 -22.541 57.603 1.00 59.35 ? 204 VAL B CG1 1 ATOM 5750 C CG2 . VAL B 1 204 ? -58.283 -23.995 58.785 1.00 60.15 ? 204 VAL B CG2 1 ATOM 5751 N N . SER B 1 205 ? -62.411 -24.930 57.289 1.00 58.66 ? 205 SER B N 1 ATOM 5752 C CA . SER B 1 205 ? -63.625 -24.675 56.569 1.00 58.11 ? 205 SER B CA 1 ATOM 5753 C C . SER B 1 205 ? -64.829 -24.970 57.449 1.00 57.92 ? 205 SER B C 1 ATOM 5754 O O . SER B 1 205 ? -65.787 -24.225 57.439 1.00 58.10 ? 205 SER B O 1 ATOM 5755 C CB . SER B 1 205 ? -63.650 -25.461 55.264 1.00 58.05 ? 205 SER B CB 1 ATOM 5756 O OG . SER B 1 205 ? -63.917 -26.830 55.479 1.00 58.49 ? 205 SER B OG 1 ATOM 5757 N N . LEU B 1 206 ? -64.770 -26.033 58.242 1.00 57.92 ? 206 LEU B N 1 ATOM 5758 C CA . LEU B 1 206 ? -65.893 -26.370 59.122 1.00 57.72 ? 206 LEU B CA 1 ATOM 5759 C C . LEU B 1 206 ? -66.153 -25.278 60.131 1.00 57.67 ? 206 LEU B C 1 ATOM 5760 O O . LEU B 1 206 ? -67.294 -25.020 60.506 1.00 57.24 ? 206 LEU B O 1 ATOM 5761 C CB . LEU B 1 206 ? -65.639 -27.683 59.844 1.00 57.50 ? 206 LEU B CB 1 ATOM 5762 C CG . LEU B 1 206 ? -66.078 -28.891 59.017 1.00 57.65 ? 206 LEU B CG 1 ATOM 5763 C CD1 . LEU B 1 206 ? -65.470 -30.152 59.573 1.00 57.51 ? 206 LEU B CD1 1 ATOM 5764 C CD2 . LEU B 1 206 ? -67.607 -29.010 58.985 1.00 58.33 ? 206 LEU B CD2 1 ATOM 5765 N N . HIS B 1 207 ? -65.078 -24.628 60.549 1.00 58.18 ? 207 HIS B N 1 ATOM 5766 C CA . HIS B 1 207 ? -65.171 -23.513 61.468 1.00 59.08 ? 207 HIS B CA 1 ATOM 5767 C C . HIS B 1 207 ? -65.945 -22.352 60.856 1.00 59.16 ? 207 HIS B C 1 ATOM 5768 O O . HIS B 1 207 ? -66.693 -21.645 61.555 1.00 59.54 ? 207 HIS B O 1 ATOM 5769 C CB . HIS B 1 207 ? -63.769 -23.066 61.904 1.00 59.27 ? 207 HIS B CB 1 ATOM 5770 C CG . HIS B 1 207 ? -63.191 -23.924 62.981 1.00 60.62 ? 207 HIS B CG 1 ATOM 5771 N ND1 . HIS B 1 207 ? -63.605 -23.844 64.296 1.00 61.16 ? 207 HIS B ND1 1 ATOM 5772 C CD2 . HIS B 1 207 ? -62.271 -24.920 62.935 1.00 61.17 ? 207 HIS B CD2 1 ATOM 5773 C CE1 . HIS B 1 207 ? -62.941 -24.734 65.017 1.00 61.10 ? 207 HIS B CE1 1 ATOM 5774 N NE2 . HIS B 1 207 ? -62.124 -25.399 64.217 1.00 60.21 ? 207 HIS B NE2 1 ATOM 5775 N N . LEU B 1 208 ? -65.761 -22.152 59.556 1.00 58.89 ? 208 LEU B N 1 ATOM 5776 C CA . LEU B 1 208 ? -66.500 -21.119 58.856 1.00 58.59 ? 208 LEU B CA 1 ATOM 5777 C C . LEU B 1 208 ? -68.003 -21.396 58.952 1.00 58.94 ? 208 LEU B C 1 ATOM 5778 O O . LEU B 1 208 ? -68.823 -20.465 58.916 1.00 58.90 ? 208 LEU B O 1 ATOM 5779 C CB . LEU B 1 208 ? -66.076 -21.086 57.396 1.00 58.37 ? 208 LEU B CB 1 ATOM 5780 C CG . LEU B 1 208 ? -64.691 -20.553 57.098 1.00 56.87 ? 208 LEU B CG 1 ATOM 5781 C CD1 . LEU B 1 208 ? -64.443 -20.711 55.615 1.00 53.97 ? 208 LEU B CD1 1 ATOM 5782 C CD2 . LEU B 1 208 ? -64.652 -19.102 57.537 1.00 55.74 ? 208 LEU B CD2 1 ATOM 5783 N N . LEU B 1 209 ? -68.365 -22.675 59.069 1.00 59.16 ? 209 LEU B N 1 ATOM 5784 C CA . LEU B 1 209 ? -69.776 -23.042 59.128 1.00 59.71 ? 209 LEU B CA 1 ATOM 5785 C C . LEU B 1 209 ? -70.267 -23.105 60.548 1.00 60.31 ? 209 LEU B C 1 ATOM 5786 O O . LEU B 1 209 ? -71.453 -22.875 60.802 1.00 60.65 ? 209 LEU B O 1 ATOM 5787 C CB . LEU B 1 209 ? -70.065 -24.370 58.438 1.00 59.42 ? 209 LEU B CB 1 ATOM 5788 C CG . LEU B 1 209 ? -69.565 -24.392 57.006 1.00 59.63 ? 209 LEU B CG 1 ATOM 5789 C CD1 . LEU B 1 209 ? -69.995 -25.665 56.270 1.00 59.23 ? 209 LEU B CD1 1 ATOM 5790 C CD2 . LEU B 1 209 ? -70.077 -23.141 56.319 1.00 60.73 ? 209 LEU B CD2 1 ATOM 5791 N N . SER B 1 210 ? -69.382 -23.419 61.487 1.00 60.92 ? 210 SER B N 1 ATOM 5792 C CA . SER B 1 210 ? -69.839 -23.471 62.880 1.00 61.48 ? 210 SER B CA 1 ATOM 5793 C C . SER B 1 210 ? -70.161 -22.090 63.401 1.00 61.44 ? 210 SER B C 1 ATOM 5794 O O . SER B 1 210 ? -69.349 -21.168 63.297 1.00 61.13 ? 210 SER B O 1 ATOM 5795 C CB . SER B 1 210 ? -68.845 -24.163 63.811 1.00 61.51 ? 210 SER B CB 1 ATOM 5796 O OG . SER B 1 210 ? -69.401 -24.275 65.107 1.00 62.47 ? 210 SER B OG 1 ATOM 5797 N N . PRO B 1 211 ? -71.382 -21.936 63.920 1.00 61.75 ? 211 PRO B N 1 ATOM 5798 C CA . PRO B 1 211 ? -71.721 -20.670 64.568 1.00 62.05 ? 211 PRO B CA 1 ATOM 5799 C C . PRO B 1 211 ? -70.875 -20.531 65.842 1.00 62.45 ? 211 PRO B C 1 ATOM 5800 O O . PRO B 1 211 ? -70.441 -19.428 66.205 1.00 62.14 ? 211 PRO B O 1 ATOM 5801 C CB . PRO B 1 211 ? -73.214 -20.816 64.888 1.00 61.67 ? 211 PRO B CB 1 ATOM 5802 C CG . PRO B 1 211 ? -73.487 -22.298 64.845 1.00 61.91 ? 211 PRO B CG 1 ATOM 5803 C CD . PRO B 1 211 ? -72.478 -22.924 63.941 1.00 61.61 ? 211 PRO B CD 1 ATOM 5804 N N . GLY B 1 212 ? -70.613 -21.664 66.487 1.00 62.89 ? 212 GLY B N 1 ATOM 5805 C CA . GLY B 1 212 ? -69.816 -21.687 67.689 1.00 63.43 ? 212 GLY B CA 1 ATOM 5806 C C . GLY B 1 212 ? -68.480 -21.002 67.510 1.00 63.72 ? 212 GLY B C 1 ATOM 5807 O O . GLY B 1 212 ? -67.887 -20.544 68.489 1.00 64.17 ? 212 GLY B O 1 ATOM 5808 N N . SER B 1 213 ? -67.999 -20.922 66.273 1.00 63.67 ? 213 SER B N 1 ATOM 5809 C CA . SER B 1 213 ? -66.670 -20.348 66.009 1.00 63.63 ? 213 SER B CA 1 ATOM 5810 C C . SER B 1 213 ? -66.722 -18.979 65.332 1.00 63.58 ? 213 SER B C 1 ATOM 5811 O O . SER B 1 213 ? -65.713 -18.280 65.250 1.00 63.17 ? 213 SER B O 1 ATOM 5812 C CB . SER B 1 213 ? -65.855 -21.306 65.141 1.00 63.80 ? 213 SER B CB 1 ATOM 5813 O OG . SER B 1 213 ? -65.766 -22.582 65.748 1.00 64.37 ? 213 SER B OG 1 ATOM 5814 N N A HIS B 1 214 ? -67.898 -18.616 64.830 0.50 63.71 ? 214 HIS B N 1 ATOM 5815 N N B HIS B 1 214 ? -67.919 -18.607 64.877 0.50 63.86 ? 214 HIS B N 1 ATOM 5816 C CA A HIS B 1 214 ? -68.063 -17.359 64.108 0.50 63.77 ? 214 HIS B CA 1 ATOM 5817 C CA B HIS B 1 214 ? -68.161 -17.375 64.110 0.50 64.04 ? 214 HIS B CA 1 ATOM 5818 C C A HIS B 1 214 ? -67.117 -16.301 64.649 0.50 63.84 ? 214 HIS B C 1 ATOM 5819 C C B HIS B 1 214 ? -67.504 -16.105 64.664 0.50 64.03 ? 214 HIS B C 1 ATOM 5820 O O A HIS B 1 214 ? -66.337 -15.705 63.901 0.50 63.99 ? 214 HIS B O 1 ATOM 5821 O O B HIS B 1 214 ? -67.305 -15.146 63.918 0.50 64.26 ? 214 HIS B O 1 ATOM 5822 C CB A HIS B 1 214 ? -69.508 -16.842 64.208 0.50 63.80 ? 214 HIS B CB 1 ATOM 5823 C CB B HIS B 1 214 ? -69.675 -17.133 63.943 0.50 64.22 ? 214 HIS B CB 1 ATOM 5824 C CG A HIS B 1 214 ? -69.777 -15.637 63.356 0.50 63.09 ? 214 HIS B CG 1 ATOM 5825 C CG B HIS B 1 214 ? -70.300 -17.882 62.801 0.50 64.03 ? 214 HIS B CG 1 ATOM 5826 N ND1 A HIS B 1 214 ? -70.780 -15.600 62.411 0.50 62.68 ? 214 HIS B ND1 1 ATOM 5827 N ND1 B HIS B 1 214 ? -69.616 -18.821 62.058 0.50 63.92 ? 214 HIS B ND1 1 ATOM 5828 C CD2 A HIS B 1 214 ? -69.156 -14.435 63.294 0.50 61.94 ? 214 HIS B CD2 1 ATOM 5829 C CD2 B HIS B 1 214 ? -71.558 -17.850 62.300 0.50 63.39 ? 214 HIS B CD2 1 ATOM 5830 C CE1 A HIS B 1 214 ? -70.769 -14.424 61.811 0.50 62.20 ? 214 HIS B CE1 1 ATOM 5831 C CE1 B HIS B 1 214 ? -70.420 -19.319 61.135 0.50 64.26 ? 214 HIS B CE1 1 ATOM 5832 N NE2 A HIS B 1 214 ? -69.792 -13.700 62.327 0.50 61.56 ? 214 HIS B NE2 1 ATOM 5833 N NE2 B HIS B 1 214 ? -71.605 -18.749 61.264 0.50 63.88 ? 214 HIS B NE2 1 ATOM 5834 N N . SER B 1 215 ? -67.186 -16.084 65.957 1.00 63.77 ? 215 SER B N 1 ATOM 5835 C CA . SER B 1 215 ? -66.565 -14.918 66.565 1.00 63.74 ? 215 SER B CA 1 ATOM 5836 C C . SER B 1 215 ? -65.191 -15.192 67.165 1.00 63.65 ? 215 SER B C 1 ATOM 5837 O O . SER B 1 215 ? -64.638 -14.359 67.886 1.00 63.55 ? 215 SER B O 1 ATOM 5838 C CB . SER B 1 215 ? -67.456 -14.419 67.687 1.00 63.85 ? 215 SER B CB 1 ATOM 5839 O OG . SER B 1 215 ? -67.253 -15.233 68.836 1.00 64.94 ? 215 SER B OG 1 ATOM 5840 N N . LEU B 1 216 ? -64.637 -16.362 66.886 1.00 63.57 ? 216 LEU B N 1 ATOM 5841 C CA . LEU B 1 216 ? -63.371 -16.738 67.510 1.00 63.19 ? 216 LEU B CA 1 ATOM 5842 C C . LEU B 1 216 ? -62.180 -16.428 66.614 1.00 63.00 ? 216 LEU B C 1 ATOM 5843 O O . LEU B 1 216 ? -61.028 -16.579 67.023 1.00 63.33 ? 216 LEU B O 1 ATOM 5844 C CB . LEU B 1 216 ? -63.409 -18.216 67.928 1.00 63.12 ? 216 LEU B CB 1 ATOM 5845 C CG . LEU B 1 216 ? -64.706 -18.497 68.725 1.00 62.88 ? 216 LEU B CG 1 ATOM 5846 C CD1 . LEU B 1 216 ? -64.952 -19.990 68.919 1.00 62.42 ? 216 LEU B CD1 1 ATOM 5847 C CD2 . LEU B 1 216 ? -64.745 -17.749 70.066 1.00 63.49 ? 216 LEU B CD2 1 ATOM 5848 N N . PHE B 1 217 ? -62.465 -15.972 65.398 1.00 62.65 ? 217 PHE B N 1 ATOM 5849 C CA . PHE B 1 217 ? -61.419 -15.648 64.432 1.00 62.29 ? 217 PHE B CA 1 ATOM 5850 C C . PHE B 1 217 ? -61.932 -14.715 63.358 1.00 61.91 ? 217 PHE B C 1 ATOM 5851 O O . PHE B 1 217 ? -63.121 -14.406 63.320 1.00 62.28 ? 217 PHE B O 1 ATOM 5852 C CB . PHE B 1 217 ? -60.884 -16.916 63.775 1.00 62.43 ? 217 PHE B CB 1 ATOM 5853 C CG . PHE B 1 217 ? -61.862 -17.576 62.830 1.00 62.67 ? 217 PHE B CG 1 ATOM 5854 C CD1 . PHE B 1 217 ? -62.986 -18.250 63.319 1.00 62.19 ? 217 PHE B CD1 1 ATOM 5855 C CD2 . PHE B 1 217 ? -61.641 -17.539 61.454 1.00 61.40 ? 217 PHE B CD2 1 ATOM 5856 C CE1 . PHE B 1 217 ? -63.869 -18.882 62.456 1.00 62.52 ? 217 PHE B CE1 1 ATOM 5857 C CE2 . PHE B 1 217 ? -62.514 -18.163 60.588 1.00 61.69 ? 217 PHE B CE2 1 ATOM 5858 C CZ . PHE B 1 217 ? -63.634 -18.837 61.082 1.00 62.31 ? 217 PHE B CZ 1 ATOM 5859 N N . THR B 1 218 ? -61.042 -14.322 62.452 1.00 61.26 ? 218 THR B N 1 ATOM 5860 C CA . THR B 1 218 ? -61.304 -13.231 61.524 1.00 60.53 ? 218 THR B CA 1 ATOM 5861 C C . THR B 1 218 ? -61.290 -13.717 60.096 1.00 60.21 ? 218 THR B C 1 ATOM 5862 O O . THR B 1 218 ? -62.280 -13.563 59.388 1.00 60.57 ? 218 THR B O 1 ATOM 5863 C CB . THR B 1 218 ? -60.229 -12.149 61.680 1.00 60.75 ? 218 THR B CB 1 ATOM 5864 O OG1 . THR B 1 218 ? -60.268 -11.638 63.028 1.00 61.17 ? 218 THR B OG1 1 ATOM 5865 C CG2 . THR B 1 218 ? -60.410 -11.032 60.661 1.00 59.81 ? 218 THR B CG2 1 ATOM 5866 N N . ARG B 1 219 ? -60.169 -14.308 59.678 1.00 59.54 ? 219 ARG B N 1 ATOM 5867 C CA . ARG B 1 219 ? -59.996 -14.794 58.309 1.00 58.63 ? 219 ARG B CA 1 ATOM 5868 C C . ARG B 1 219 ? -59.635 -16.283 58.230 1.00 58.33 ? 219 ARG B C 1 ATOM 5869 O O . ARG B 1 219 ? -59.438 -16.927 59.266 1.00 58.85 ? 219 ARG B O 1 ATOM 5870 C CB . ARG B 1 219 ? -58.926 -13.974 57.638 1.00 58.61 ? 219 ARG B CB 1 ATOM 5871 C CG . ARG B 1 219 ? -59.467 -12.725 57.008 1.00 58.25 ? 219 ARG B CG 1 ATOM 5872 C CD . ARG B 1 219 ? -58.361 -12.001 56.284 1.00 58.38 ? 219 ARG B CD 1 ATOM 5873 N NE . ARG B 1 219 ? -57.817 -10.966 57.140 1.00 59.12 ? 219 ARG B NE 1 ATOM 5874 C CZ . ARG B 1 219 ? -58.519 -9.922 57.576 1.00 59.56 ? 219 ARG B CZ 1 ATOM 5875 N NH1 . ARG B 1 219 ? -57.939 -9.016 58.351 1.00 60.57 ? 219 ARG B NH1 1 ATOM 5876 N NH2 . ARG B 1 219 ? -59.796 -9.779 57.238 1.00 59.42 ? 219 ARG B NH2 1 ATOM 5877 N N . ALA B 1 220 ? -59.550 -16.837 57.014 1.00 57.38 ? 220 ALA B N 1 ATOM 5878 C CA . ALA B 1 220 ? -59.286 -18.279 56.846 1.00 56.13 ? 220 ALA B CA 1 ATOM 5879 C C . ALA B 1 220 ? -58.405 -18.587 55.648 1.00 55.50 ? 220 ALA B C 1 ATOM 5880 O O . ALA B 1 220 ? -58.461 -17.904 54.634 1.00 55.27 ? 220 ALA B O 1 ATOM 5881 C CB . ALA B 1 220 ? -60.582 -19.049 56.762 1.00 55.67 ? 220 ALA B CB 1 ATOM 5882 N N . ILE B 1 221 ? -57.570 -19.604 55.792 1.00 55.04 ? 221 ILE B N 1 ATOM 5883 C CA . ILE B 1 221 ? -56.735 -20.086 54.706 1.00 55.06 ? 221 ILE B CA 1 ATOM 5884 C C . ILE B 1 221 ? -56.914 -21.579 54.687 1.00 55.43 ? 221 ILE B C 1 ATOM 5885 O O . ILE B 1 221 ? -56.998 -22.210 55.748 1.00 55.80 ? 221 ILE B O 1 ATOM 5886 C CB . ILE B 1 221 ? -55.265 -19.798 54.915 1.00 54.85 ? 221 ILE B CB 1 ATOM 5887 C CG1 . ILE B 1 221 ? -55.064 -18.292 54.974 1.00 55.67 ? 221 ILE B CG1 1 ATOM 5888 C CG2 . ILE B 1 221 ? -54.456 -20.385 53.785 1.00 53.64 ? 221 ILE B CG2 1 ATOM 5889 C CD1 . ILE B 1 221 ? -53.826 -17.891 55.734 1.00 55.85 ? 221 ILE B CD1 1 ATOM 5890 N N . LEU B 1 222 ? -57.000 -22.138 53.483 1.00 55.26 ? 222 LEU B N 1 ATOM 5891 C CA . LEU B 1 222 ? -57.316 -23.530 53.301 1.00 54.98 ? 222 LEU B CA 1 ATOM 5892 C C . LEU B 1 222 ? -56.309 -24.100 52.328 1.00 55.31 ? 222 LEU B C 1 ATOM 5893 O O . LEU B 1 222 ? -56.325 -23.774 51.136 1.00 55.79 ? 222 LEU B O 1 ATOM 5894 C CB . LEU B 1 222 ? -58.742 -23.671 52.769 1.00 54.54 ? 222 LEU B CB 1 ATOM 5895 C CG . LEU B 1 222 ? -59.884 -23.497 53.790 1.00 54.55 ? 222 LEU B CG 1 ATOM 5896 C CD1 . LEU B 1 222 ? -59.886 -22.132 54.439 1.00 53.29 ? 222 LEU B CD1 1 ATOM 5897 C CD2 . LEU B 1 222 ? -61.252 -23.769 53.180 1.00 53.70 ? 222 LEU B CD2 1 ATOM 5898 N N . GLN B 1 223 ? -55.404 -24.928 52.834 1.00 55.43 ? 223 GLN B N 1 ATOM 5899 C CA . GLN B 1 223 ? -54.399 -25.554 51.971 1.00 55.65 ? 223 GLN B CA 1 ATOM 5900 C C . GLN B 1 223 ? -54.706 -27.023 51.727 1.00 55.68 ? 223 GLN B C 1 ATOM 5901 O O . GLN B 1 223 ? -54.909 -27.804 52.677 1.00 55.34 ? 223 GLN B O 1 ATOM 5902 C CB . GLN B 1 223 ? -53.016 -25.399 52.571 1.00 55.86 ? 223 GLN B CB 1 ATOM 5903 C CG . GLN B 1 223 ? -52.790 -24.020 53.140 1.00 56.46 ? 223 GLN B CG 1 ATOM 5904 C CD . GLN B 1 223 ? -51.383 -23.837 53.643 1.00 57.47 ? 223 GLN B CD 1 ATOM 5905 O OE1 . GLN B 1 223 ? -51.095 -22.904 54.405 1.00 57.52 ? 223 GLN B OE1 1 ATOM 5906 N NE2 . GLN B 1 223 ? -50.480 -24.732 53.214 1.00 58.95 ? 223 GLN B NE2 1 ATOM 5907 N N . SER B 1 224 ? -54.741 -27.381 50.440 1.00 55.61 ? 224 SER B N 1 ATOM 5908 C CA . SER B 1 224 ? -55.242 -28.681 49.998 1.00 55.17 ? 224 SER B CA 1 ATOM 5909 C C . SER B 1 224 ? -56.273 -29.258 50.985 1.00 55.37 ? 224 SER B C 1 ATOM 5910 O O . SER B 1 224 ? -55.960 -30.147 51.784 1.00 55.41 ? 224 SER B O 1 ATOM 5911 C CB . SER B 1 224 ? -54.079 -29.642 49.787 1.00 54.84 ? 224 SER B CB 1 ATOM 5912 O OG . SER B 1 224 ? -53.010 -28.964 49.158 1.00 53.59 ? 224 SER B OG 1 ATOM 5913 N N . GLY B 1 225 ? -57.502 -28.750 50.937 1.00 55.17 ? 225 GLY B N 1 ATOM 5914 C CA . GLY B 1 225 ? -58.552 -29.345 51.746 1.00 55.34 ? 225 GLY B CA 1 ATOM 5915 C C . GLY B 1 225 ? -59.743 -28.461 52.023 1.00 55.45 ? 225 GLY B C 1 ATOM 5916 O O . GLY B 1 225 ? -59.607 -27.235 52.101 1.00 55.77 ? 225 GLY B O 1 ATOM 5917 N N . SER B 1 226 ? -60.895 -29.106 52.226 1.00 55.39 ? 226 SER B N 1 ATOM 5918 C CA . SER B 1 226 ? -62.194 -28.443 52.377 1.00 55.31 ? 226 SER B CA 1 ATOM 5919 C C . SER B 1 226 ? -63.256 -29.460 52.794 1.00 55.28 ? 226 SER B C 1 ATOM 5920 O O . SER B 1 226 ? -63.227 -30.619 52.386 1.00 55.05 ? 226 SER B O 1 ATOM 5921 C CB . SER B 1 226 ? -62.586 -27.849 51.040 1.00 55.19 ? 226 SER B CB 1 ATOM 5922 O OG . SER B 1 226 ? -61.982 -28.639 50.032 1.00 55.78 ? 226 SER B OG 1 ATOM 5923 N N . PHE B 1 227 ? -64.212 -29.035 53.599 1.00 55.37 ? 227 PHE B N 1 ATOM 5924 C CA . PHE B 1 227 ? -65.151 -30.003 54.148 1.00 55.63 ? 227 PHE B CA 1 ATOM 5925 C C . PHE B 1 227 ? -65.851 -30.796 53.062 1.00 55.18 ? 227 PHE B C 1 ATOM 5926 O O . PHE B 1 227 ? -66.111 -31.997 53.221 1.00 54.88 ? 227 PHE B O 1 ATOM 5927 C CB . PHE B 1 227 ? -66.175 -29.323 55.044 1.00 55.83 ? 227 PHE B CB 1 ATOM 5928 C CG . PHE B 1 227 ? -67.256 -28.609 54.296 1.00 57.25 ? 227 PHE B CG 1 ATOM 5929 C CD1 . PHE B 1 227 ? -67.228 -27.223 54.169 1.00 58.50 ? 227 PHE B CD1 1 ATOM 5930 C CD2 . PHE B 1 227 ? -68.318 -29.310 53.751 1.00 58.55 ? 227 PHE B CD2 1 ATOM 5931 C CE1 . PHE B 1 227 ? -68.250 -26.535 53.507 1.00 58.24 ? 227 PHE B CE1 1 ATOM 5932 C CE2 . PHE B 1 227 ? -69.341 -28.643 53.084 1.00 59.49 ? 227 PHE B CE2 1 ATOM 5933 C CZ . PHE B 1 227 ? -69.304 -27.246 52.963 1.00 59.47 ? 227 PHE B CZ 1 ATOM 5934 N N . ASN B 1 228 ? -66.155 -30.116 51.960 1.00 55.25 ? 228 ASN B N 1 ATOM 5935 C CA . ASN B 1 228 ? -66.855 -30.741 50.829 1.00 55.04 ? 228 ASN B CA 1 ATOM 5936 C C . ASN B 1 228 ? -66.059 -31.839 50.103 1.00 54.88 ? 228 ASN B C 1 ATOM 5937 O O . ASN B 1 228 ? -66.571 -32.438 49.197 1.00 54.74 ? 228 ASN B O 1 ATOM 5938 C CB . ASN B 1 228 ? -67.287 -29.678 49.828 1.00 54.86 ? 228 ASN B CB 1 ATOM 5939 C CG . ASN B 1 228 ? -66.096 -28.953 49.208 1.00 55.33 ? 228 ASN B CG 1 ATOM 5940 O OD1 . ASN B 1 228 ? -65.103 -28.682 49.885 1.00 54.93 ? 228 ASN B OD1 1 ATOM 5941 N ND2 . ASN B 1 228 ? -66.191 -28.639 47.915 1.00 56.09 ? 228 ASN B ND2 1 ATOM 5942 N N . ALA B 1 229 ? -64.818 -32.100 50.505 1.00 55.07 ? 229 ALA B N 1 ATOM 5943 C CA . ALA B 1 229 ? -64.040 -33.231 49.964 1.00 54.79 ? 229 ALA B CA 1 ATOM 5944 C C . ALA B 1 229 ? -64.637 -34.564 50.340 1.00 54.42 ? 229 ALA B C 1 ATOM 5945 O O . ALA B 1 229 ? -65.211 -34.715 51.413 1.00 54.18 ? 229 ALA B O 1 ATOM 5946 C CB . ALA B 1 229 ? -62.587 -33.188 50.448 1.00 55.07 ? 229 ALA B CB 1 ATOM 5947 N N . PRO B 1 230 ? -64.477 -35.551 49.462 1.00 54.52 ? 230 PRO B N 1 ATOM 5948 C CA . PRO B 1 230 ? -65.172 -36.790 49.704 1.00 54.56 ? 230 PRO B CA 1 ATOM 5949 C C . PRO B 1 230 ? -64.779 -37.383 51.053 1.00 54.90 ? 230 PRO B C 1 ATOM 5950 O O . PRO B 1 230 ? -65.605 -37.989 51.741 1.00 54.76 ? 230 PRO B O 1 ATOM 5951 C CB . PRO B 1 230 ? -64.724 -37.681 48.549 1.00 54.32 ? 230 PRO B CB 1 ATOM 5952 C CG . PRO B 1 230 ? -63.505 -37.062 48.003 1.00 54.45 ? 230 PRO B CG 1 ATOM 5953 C CD . PRO B 1 230 ? -63.633 -35.600 48.258 1.00 54.64 ? 230 PRO B CD 1 ATOM 5954 N N . TRP B 1 231 ? -63.542 -37.174 51.467 1.00 55.48 ? 231 TRP B N 1 ATOM 5955 C CA . TRP B 1 231 ? -63.081 -37.844 52.676 1.00 55.88 ? 231 TRP B CA 1 ATOM 5956 C C . TRP B 1 231 ? -63.364 -37.135 54.009 1.00 56.67 ? 231 TRP B C 1 ATOM 5957 O O . TRP B 1 231 ? -62.925 -37.599 55.035 1.00 56.76 ? 231 TRP B O 1 ATOM 5958 C CB . TRP B 1 231 ? -61.591 -38.089 52.549 1.00 55.19 ? 231 TRP B CB 1 ATOM 5959 C CG . TRP B 1 231 ? -60.824 -36.877 52.146 1.00 53.23 ? 231 TRP B CG 1 ATOM 5960 C CD1 . TRP B 1 231 ? -60.297 -36.618 50.922 1.00 52.52 ? 231 TRP B CD1 1 ATOM 5961 C CD2 . TRP B 1 231 ? -60.474 -35.760 52.982 1.00 52.42 ? 231 TRP B CD2 1 ATOM 5962 N NE1 . TRP B 1 231 ? -59.623 -35.409 50.935 1.00 52.07 ? 231 TRP B NE1 1 ATOM 5963 C CE2 . TRP B 1 231 ? -59.720 -34.863 52.187 1.00 51.21 ? 231 TRP B CE2 1 ATOM 5964 C CE3 . TRP B 1 231 ? -60.723 -35.433 54.329 1.00 52.35 ? 231 TRP B CE3 1 ATOM 5965 C CZ2 . TRP B 1 231 ? -59.211 -33.667 52.685 1.00 50.19 ? 231 TRP B CZ2 1 ATOM 5966 C CZ3 . TRP B 1 231 ? -60.212 -34.236 54.825 1.00 51.85 ? 231 TRP B CZ3 1 ATOM 5967 C CH2 . TRP B 1 231 ? -59.464 -33.368 53.999 1.00 51.40 ? 231 TRP B CH2 1 ATOM 5968 N N . ALA B 1 232 ? -64.100 -36.037 53.998 1.00 57.82 ? 232 ALA B N 1 ATOM 5969 C CA . ALA B 1 232 ? -64.044 -35.118 55.115 1.00 59.57 ? 232 ALA B CA 1 ATOM 5970 C C . ALA B 1 232 ? -65.232 -35.146 56.102 1.00 61.46 ? 232 ALA B C 1 ATOM 5971 O O . ALA B 1 232 ? -65.109 -34.761 57.281 1.00 61.71 ? 232 ALA B O 1 ATOM 5972 C CB . ALA B 1 232 ? -63.852 -33.746 54.600 1.00 59.54 ? 232 ALA B CB 1 ATOM 5973 N N . VAL B 1 233 ? -66.390 -35.589 55.651 1.00 63.41 ? 233 VAL B N 1 ATOM 5974 C CA . VAL B 1 233 ? -67.501 -35.662 56.578 1.00 65.27 ? 233 VAL B CA 1 ATOM 5975 C C . VAL B 1 233 ? -68.170 -37.012 56.464 1.00 66.84 ? 233 VAL B C 1 ATOM 5976 O O . VAL B 1 233 ? -68.215 -37.586 55.407 1.00 66.99 ? 233 VAL B O 1 ATOM 5977 C CB . VAL B 1 233 ? -68.478 -34.484 56.376 1.00 65.08 ? 233 VAL B CB 1 ATOM 5978 C CG1 . VAL B 1 233 ? -69.620 -34.538 57.379 1.00 65.24 ? 233 VAL B CG1 1 ATOM 5979 C CG2 . VAL B 1 233 ? -67.730 -33.170 56.516 1.00 64.63 ? 233 VAL B CG2 1 ATOM 5980 N N . THR B 1 234 ? -68.648 -37.542 57.572 1.00 69.52 ? 234 THR B N 1 ATOM 5981 C CA . THR B 1 234 ? -69.229 -38.866 57.583 1.00 72.15 ? 234 THR B CA 1 ATOM 5982 C C . THR B 1 234 ? -70.718 -38.752 57.803 1.00 73.96 ? 234 THR B C 1 ATOM 5983 O O . THR B 1 234 ? -71.176 -37.911 58.593 1.00 74.02 ? 234 THR B O 1 ATOM 5984 C CB . THR B 1 234 ? -68.668 -39.665 58.728 1.00 72.11 ? 234 THR B CB 1 ATOM 5985 O OG1 . THR B 1 234 ? -67.239 -39.588 58.688 1.00 73.30 ? 234 THR B OG1 1 ATOM 5986 C CG2 . THR B 1 234 ? -69.117 -41.103 58.632 1.00 72.47 ? 234 THR B CG2 1 ATOM 5987 N N . SER B 1 235 ? -71.480 -39.586 57.099 1.00 76.24 ? 235 SER B N 1 ATOM 5988 C CA . SER B 1 235 ? -72.924 -39.549 57.250 1.00 78.53 ? 235 SER B CA 1 ATOM 5989 C C . SER B 1 235 ? -73.249 -40.058 58.631 1.00 80.35 ? 235 SER B C 1 ATOM 5990 O O . SER B 1 235 ? -72.519 -40.881 59.184 1.00 80.83 ? 235 SER B O 1 ATOM 5991 C CB . SER B 1 235 ? -73.637 -40.393 56.187 1.00 78.38 ? 235 SER B CB 1 ATOM 5992 O OG . SER B 1 235 ? -73.392 -41.784 56.332 1.00 78.23 ? 235 SER B OG 1 ATOM 5993 N N . LEU B 1 236 ? -74.345 -39.566 59.188 1.00 82.54 ? 236 LEU B N 1 ATOM 5994 C CA . LEU B 1 236 ? -74.810 -40.010 60.490 1.00 84.76 ? 236 LEU B CA 1 ATOM 5995 C C . LEU B 1 236 ? -75.053 -41.517 60.566 1.00 86.04 ? 236 LEU B C 1 ATOM 5996 O O . LEU B 1 236 ? -75.193 -42.082 61.636 1.00 86.14 ? 236 LEU B O 1 ATOM 5997 C CB . LEU B 1 236 ? -76.110 -39.301 60.807 1.00 84.97 ? 236 LEU B CB 1 ATOM 5998 C CG . LEU B 1 236 ? -76.377 -39.151 62.290 1.00 85.71 ? 236 LEU B CG 1 ATOM 5999 C CD1 . LEU B 1 236 ? -75.490 -38.025 62.829 1.00 85.89 ? 236 LEU B CD1 1 ATOM 6000 C CD2 . LEU B 1 236 ? -77.867 -38.862 62.500 1.00 86.28 ? 236 LEU B CD2 1 ATOM 6001 N N . TYR B 1 237 ? -75.118 -42.155 59.411 1.00 87.90 ? 237 TYR B N 1 ATOM 6002 C CA . TYR B 1 237 ? -75.351 -43.578 59.334 1.00 89.86 ? 237 TYR B CA 1 ATOM 6003 C C . TYR B 1 237 ? -74.038 -44.333 59.576 1.00 90.11 ? 237 TYR B C 1 ATOM 6004 O O . TYR B 1 237 ? -73.956 -45.147 60.501 1.00 90.54 ? 237 TYR B O 1 ATOM 6005 C CB . TYR B 1 237 ? -76.008 -43.930 57.982 1.00 90.68 ? 237 TYR B CB 1 ATOM 6006 C CG . TYR B 1 237 ? -76.169 -45.414 57.698 1.00 94.31 ? 237 TYR B CG 1 ATOM 6007 C CD1 . TYR B 1 237 ? -75.907 -45.935 56.423 1.00 96.65 ? 237 TYR B CD1 1 ATOM 6008 C CD2 . TYR B 1 237 ? -76.568 -46.303 58.707 1.00 97.19 ? 237 TYR B CD2 1 ATOM 6009 C CE1 . TYR B 1 237 ? -76.045 -47.310 56.158 1.00 98.68 ? 237 TYR B CE1 1 ATOM 6010 C CE2 . TYR B 1 237 ? -76.702 -47.680 58.452 1.00 98.94 ? 237 TYR B CE2 1 ATOM 6011 C CZ . TYR B 1 237 ? -76.439 -48.176 57.176 1.00 99.62 ? 237 TYR B CZ 1 ATOM 6012 O OH . TYR B 1 237 ? -76.571 -49.526 56.916 1.00 99.80 ? 237 TYR B OH 1 ATOM 6013 N N . GLU B 1 238 ? -73.010 -44.065 58.773 1.00 90.34 ? 238 GLU B N 1 ATOM 6014 C CA . GLU B 1 238 ? -71.735 -44.754 58.955 1.00 90.78 ? 238 GLU B CA 1 ATOM 6015 C C . GLU B 1 238 ? -71.177 -44.437 60.324 1.00 90.87 ? 238 GLU B C 1 ATOM 6016 O O . GLU B 1 238 ? -70.621 -45.298 61.010 1.00 90.67 ? 238 GLU B O 1 ATOM 6017 C CB . GLU B 1 238 ? -70.730 -44.333 57.898 1.00 90.81 ? 238 GLU B CB 1 ATOM 6018 C CG . GLU B 1 238 ? -71.239 -44.460 56.507 1.00 92.26 ? 238 GLU B CG 1 ATOM 6019 C CD . GLU B 1 238 ? -70.646 -43.408 55.606 1.00 94.76 ? 238 GLU B CD 1 ATOM 6020 O OE1 . GLU B 1 238 ? -70.670 -42.203 55.981 1.00 95.81 ? 238 GLU B OE1 1 ATOM 6021 O OE2 . GLU B 1 238 ? -70.157 -43.790 54.516 1.00 95.63 ? 238 GLU B OE2 1 ATOM 6022 N N . ALA B 1 239 ? -71.322 -43.181 60.722 1.00 91.18 ? 239 ALA B N 1 ATOM 6023 C CA . ALA B 1 239 ? -70.876 -42.767 62.033 1.00 91.48 ? 239 ALA B CA 1 ATOM 6024 C C . ALA B 1 239 ? -71.311 -43.826 63.031 1.00 91.73 ? 239 ALA B C 1 ATOM 6025 O O . ALA B 1 239 ? -70.494 -44.327 63.802 1.00 92.06 ? 239 ALA B O 1 ATOM 6026 C CB . ALA B 1 239 ? -71.464 -41.422 62.391 1.00 91.45 ? 239 ALA B CB 1 ATOM 6027 N N . ARG B 1 240 ? -72.597 -44.169 63.011 1.00 91.76 ? 240 ARG B N 1 ATOM 6028 C CA . ARG B 1 240 ? -73.115 -45.227 63.877 1.00 91.86 ? 240 ARG B CA 1 ATOM 6029 C C . ARG B 1 240 ? -72.571 -46.613 63.541 1.00 91.56 ? 240 ARG B C 1 ATOM 6030 O O . ARG B 1 240 ? -72.008 -47.268 64.415 1.00 91.61 ? 240 ARG B O 1 ATOM 6031 C CB . ARG B 1 240 ? -74.642 -45.267 63.865 1.00 92.16 ? 240 ARG B CB 1 ATOM 6032 C CG . ARG B 1 240 ? -75.316 -44.259 64.820 1.00 93.30 ? 240 ARG B CG 1 ATOM 6033 C CD . ARG B 1 240 ? -76.493 -44.880 65.615 1.00 94.18 ? 240 ARG B CD 1 ATOM 6034 N NE . ARG B 1 240 ? -77.153 -45.976 64.889 1.00 94.22 ? 240 ARG B NE 1 ATOM 6035 C CZ . ARG B 1 240 ? -77.719 -47.037 65.466 1.00 93.96 ? 240 ARG B CZ 1 ATOM 6036 N NH1 . ARG B 1 240 ? -78.290 -47.978 64.720 1.00 93.62 ? 240 ARG B NH1 1 ATOM 6037 N NH2 . ARG B 1 240 ? -77.714 -47.162 66.790 1.00 93.76 ? 240 ARG B NH2 1 ATOM 6038 N N . ASN B 1 241 ? -72.761 -47.073 62.300 1.00 91.11 ? 241 ASN B N 1 ATOM 6039 C CA . ASN B 1 241 ? -72.263 -48.395 61.891 1.00 90.77 ? 241 ASN B CA 1 ATOM 6040 C C . ASN B 1 241 ? -70.854 -48.631 62.419 1.00 89.47 ? 241 ASN B C 1 ATOM 6041 O O . ASN B 1 241 ? -70.512 -49.737 62.828 1.00 89.36 ? 241 ASN B O 1 ATOM 6042 C CB . ASN B 1 241 ? -72.269 -48.563 60.360 1.00 91.64 ? 241 ASN B CB 1 ATOM 6043 C CG . ASN B 1 241 ? -72.402 -50.028 59.923 1.00 94.70 ? 241 ASN B CG 1 ATOM 6044 O OD1 . ASN B 1 241 ? -73.408 -50.666 60.208 1.00 95.73 ? 241 ASN B OD1 1 ATOM 6045 N ND2 . ASN B 1 241 ? -71.401 -50.548 59.207 1.00 100.31 ? 241 ASN B ND2 1 ATOM 6046 N N . ARG B 1 242 ? -70.047 -47.573 62.423 1.00 88.01 ? 242 ARG B N 1 ATOM 6047 C CA . ARG B 1 242 ? -68.646 -47.667 62.804 1.00 86.46 ? 242 ARG B CA 1 ATOM 6048 C C . ARG B 1 242 ? -68.469 -47.689 64.315 1.00 85.92 ? 242 ARG B C 1 ATOM 6049 O O . ARG B 1 242 ? -67.611 -48.389 64.850 1.00 85.75 ? 242 ARG B O 1 ATOM 6050 C CB . ARG B 1 242 ? -67.865 -46.514 62.190 1.00 86.07 ? 242 ARG B CB 1 ATOM 6051 C CG . ARG B 1 242 ? -67.659 -46.698 60.721 1.00 84.66 ? 242 ARG B CG 1 ATOM 6052 C CD . ARG B 1 242 ? -67.263 -45.413 60.062 1.00 82.37 ? 242 ARG B CD 1 ATOM 6053 N NE . ARG B 1 242 ? -67.388 -45.510 58.617 1.00 79.54 ? 242 ARG B NE 1 ATOM 6054 C CZ . ARG B 1 242 ? -66.899 -44.616 57.770 1.00 77.88 ? 242 ARG B CZ 1 ATOM 6055 N NH1 . ARG B 1 242 ? -66.247 -43.561 58.225 1.00 76.62 ? 242 ARG B NH1 1 ATOM 6056 N NH2 . ARG B 1 242 ? -67.054 -44.785 56.467 1.00 78.20 ? 242 ARG B NH2 1 ATOM 6057 N N . THR B 1 243 ? -69.295 -46.923 65.006 1.00 85.23 ? 243 THR B N 1 ATOM 6058 C CA . THR B 1 243 ? -69.247 -46.925 66.439 1.00 84.56 ? 243 THR B CA 1 ATOM 6059 C C . THR B 1 243 ? -69.654 -48.292 66.921 1.00 84.39 ? 243 THR B C 1 ATOM 6060 O O . THR B 1 243 ? -69.069 -48.798 67.855 1.00 84.67 ? 243 THR B O 1 ATOM 6061 C CB . THR B 1 243 ? -70.169 -45.886 67.040 1.00 84.50 ? 243 THR B CB 1 ATOM 6062 O OG1 . THR B 1 243 ? -69.697 -44.582 66.685 1.00 84.34 ? 243 THR B OG1 1 ATOM 6063 C CG2 . THR B 1 243 ? -70.179 -46.020 68.546 1.00 84.13 ? 243 THR B CG2 1 ATOM 6064 N N . LEU B 1 244 ? -70.641 -48.905 66.276 1.00 84.00 ? 244 LEU B N 1 ATOM 6065 C CA . LEU B 1 244 ? -71.049 -50.253 66.660 1.00 83.51 ? 244 LEU B CA 1 ATOM 6066 C C . LEU B 1 244 ? -69.999 -51.269 66.268 1.00 83.57 ? 244 LEU B C 1 ATOM 6067 O O . LEU B 1 244 ? -69.630 -52.130 67.064 1.00 83.73 ? 244 LEU B O 1 ATOM 6068 C CB . LEU B 1 244 ? -72.383 -50.641 66.037 1.00 83.24 ? 244 LEU B CB 1 ATOM 6069 C CG . LEU B 1 244 ? -73.557 -49.701 66.271 1.00 82.84 ? 244 LEU B CG 1 ATOM 6070 C CD1 . LEU B 1 244 ? -74.818 -50.394 65.827 1.00 82.15 ? 244 LEU B CD1 1 ATOM 6071 C CD2 . LEU B 1 244 ? -73.655 -49.271 67.729 1.00 82.47 ? 244 LEU B CD2 1 ATOM 6072 N N . ASN B 1 245 ? -69.519 -51.181 65.037 1.00 83.49 ? 245 ASN B N 1 ATOM 6073 C CA . ASN B 1 245 ? -68.510 -52.115 64.590 1.00 83.76 ? 245 ASN B CA 1 ATOM 6074 C C . ASN B 1 245 ? -67.321 -52.132 65.528 1.00 83.89 ? 245 ASN B C 1 ATOM 6075 O O . ASN B 1 245 ? -66.764 -53.191 65.841 1.00 83.94 ? 245 ASN B O 1 ATOM 6076 C CB . ASN B 1 245 ? -68.060 -51.776 63.179 1.00 83.96 ? 245 ASN B CB 1 ATOM 6077 C CG . ASN B 1 245 ? -69.082 -52.175 62.147 1.00 85.01 ? 245 ASN B CG 1 ATOM 6078 O OD1 . ASN B 1 245 ? -70.160 -52.667 62.496 1.00 86.49 ? 245 ASN B OD1 1 ATOM 6079 N ND2 . ASN B 1 245 ? -68.761 -51.972 60.873 1.00 85.80 ? 245 ASN B ND2 1 ATOM 6080 N N . LEU B 1 246 ? -66.931 -50.951 65.984 1.00 83.94 ? 246 LEU B N 1 ATOM 6081 C CA . LEU B 1 246 ? -65.823 -50.863 66.906 1.00 83.95 ? 246 LEU B CA 1 ATOM 6082 C C . LEU B 1 246 ? -66.201 -51.570 68.192 1.00 84.08 ? 246 LEU B C 1 ATOM 6083 O O . LEU B 1 246 ? -65.377 -52.246 68.788 1.00 84.17 ? 246 LEU B O 1 ATOM 6084 C CB . LEU B 1 246 ? -65.472 -49.405 67.180 1.00 83.84 ? 246 LEU B CB 1 ATOM 6085 C CG . LEU B 1 246 ? -64.280 -49.156 68.098 1.00 83.27 ? 246 LEU B CG 1 ATOM 6086 C CD1 . LEU B 1 246 ? -62.956 -49.310 67.349 1.00 82.22 ? 246 LEU B CD1 1 ATOM 6087 C CD2 . LEU B 1 246 ? -64.412 -47.768 68.698 1.00 82.45 ? 246 LEU B CD2 1 ATOM 6088 N N . ALA B 1 247 ? -67.455 -51.429 68.606 1.00 84.39 ? 247 ALA B N 1 ATOM 6089 C CA . ALA B 1 247 ? -67.902 -52.046 69.845 1.00 85.09 ? 247 ALA B CA 1 ATOM 6090 C C . ALA B 1 247 ? -67.797 -53.547 69.730 1.00 85.62 ? 247 ALA B C 1 ATOM 6091 O O . ALA B 1 247 ? -67.160 -54.194 70.557 1.00 85.60 ? 247 ALA B O 1 ATOM 6092 C CB . ALA B 1 247 ? -69.327 -51.631 70.198 1.00 84.87 ? 247 ALA B CB 1 ATOM 6093 N N . LYS B 1 248 ? -68.406 -54.103 68.692 1.00 86.49 ? 248 LYS B N 1 ATOM 6094 C CA . LYS B 1 248 ? -68.273 -55.528 68.463 1.00 87.35 ? 248 LYS B CA 1 ATOM 6095 C C . LYS B 1 248 ? -66.804 -55.930 68.488 1.00 87.50 ? 248 LYS B C 1 ATOM 6096 O O . LYS B 1 248 ? -66.423 -56.791 69.265 1.00 87.81 ? 248 LYS B O 1 ATOM 6097 C CB . LYS B 1 248 ? -68.924 -55.960 67.151 1.00 87.59 ? 248 LYS B CB 1 ATOM 6098 C CG . LYS B 1 248 ? -68.288 -57.223 66.583 1.00 89.08 ? 248 LYS B CG 1 ATOM 6099 C CD . LYS B 1 248 ? -69.280 -58.133 65.844 1.00 91.11 ? 248 LYS B CD 1 ATOM 6100 C CE . LYS B 1 248 ? -68.532 -59.289 65.147 1.00 92.24 ? 248 LYS B CE 1 ATOM 6101 N NZ . LYS B 1 248 ? -69.341 -60.547 65.018 1.00 93.25 ? 248 LYS B NZ 1 ATOM 6102 N N . LEU B 1 249 ? -65.983 -55.291 67.659 1.00 87.76 ? 249 LEU B N 1 ATOM 6103 C CA . LEU B 1 249 ? -64.553 -55.607 67.580 1.00 88.01 ? 249 LEU B CA 1 ATOM 6104 C C . LEU B 1 249 ? -63.777 -55.605 68.899 1.00 88.26 ? 249 LEU B C 1 ATOM 6105 O O . LEU B 1 249 ? -62.653 -56.086 68.947 1.00 88.21 ? 249 LEU B O 1 ATOM 6106 C CB . LEU B 1 249 ? -63.854 -54.657 66.616 1.00 87.93 ? 249 LEU B CB 1 ATOM 6107 C CG . LEU B 1 249 ? -63.930 -55.020 65.141 1.00 88.29 ? 249 LEU B CG 1 ATOM 6108 C CD1 . LEU B 1 249 ? -63.752 -53.761 64.329 1.00 89.38 ? 249 LEU B CD1 1 ATOM 6109 C CD2 . LEU B 1 249 ? -62.871 -56.055 64.764 1.00 88.66 ? 249 LEU B CD2 1 ATOM 6110 N N . THR B 1 250 ? -64.350 -55.044 69.956 1.00 88.70 ? 250 THR B N 1 ATOM 6111 C CA . THR B 1 250 ? -63.681 -55.042 71.250 1.00 89.18 ? 250 THR B CA 1 ATOM 6112 C C . THR B 1 250 ? -64.588 -55.657 72.297 1.00 89.73 ? 250 THR B C 1 ATOM 6113 O O . THR B 1 250 ? -64.481 -55.350 73.483 1.00 89.52 ? 250 THR B O 1 ATOM 6114 C CB . THR B 1 250 ? -63.296 -53.611 71.685 1.00 89.28 ? 250 THR B CB 1 ATOM 6115 O OG1 . THR B 1 250 ? -64.466 -52.881 72.096 1.00 88.82 ? 250 THR B OG1 1 ATOM 6116 C CG2 . THR B 1 250 ? -62.601 -52.888 70.544 1.00 88.83 ? 250 THR B CG2 1 ATOM 6117 N N . GLY B 1 251 ? -65.491 -56.516 71.838 1.00 90.62 ? 251 GLY B N 1 ATOM 6118 C CA . GLY B 1 251 ? -66.529 -57.094 72.683 1.00 91.91 ? 251 GLY B CA 1 ATOM 6119 C C . GLY B 1 251 ? -67.268 -56.064 73.520 1.00 92.93 ? 251 GLY B C 1 ATOM 6120 O O . GLY B 1 251 ? -67.429 -56.231 74.723 1.00 92.91 ? 251 GLY B O 1 ATOM 6121 N N . CYS B 1 252 ? -67.731 -54.992 72.894 1.00 93.98 ? 252 CYS B N 1 ATOM 6122 C CA . CYS B 1 252 ? -68.376 -53.939 73.657 1.00 95.05 ? 252 CYS B CA 1 ATOM 6123 C C . CYS B 1 252 ? -69.851 -53.761 73.318 1.00 95.85 ? 252 CYS B C 1 ATOM 6124 O O . CYS B 1 252 ? -70.505 -52.853 73.849 1.00 96.09 ? 252 CYS B O 1 ATOM 6125 C CB . CYS B 1 252 ? -67.638 -52.617 73.470 1.00 95.19 ? 252 CYS B CB 1 ATOM 6126 S SG . CYS B 1 252 ? -66.299 -52.317 74.627 1.00 95.35 ? 252 CYS B SG 1 ATOM 6127 N N . SER B 1 253 ? -70.368 -54.626 72.446 1.00 96.63 ? 253 SER B N 1 ATOM 6128 C CA . SER B 1 253 ? -71.774 -54.574 72.025 1.00 97.51 ? 253 SER B CA 1 ATOM 6129 C C . SER B 1 253 ? -72.700 -54.530 73.239 1.00 98.28 ? 253 SER B C 1 ATOM 6130 O O . SER B 1 253 ? -72.341 -55.031 74.298 1.00 98.39 ? 253 SER B O 1 ATOM 6131 C CB . SER B 1 253 ? -72.101 -55.782 71.144 1.00 97.44 ? 253 SER B CB 1 ATOM 6132 O OG . SER B 1 253 ? -71.063 -56.009 70.204 1.00 96.90 ? 253 SER B OG 1 ATOM 6133 N N . ARG B 1 254 ? -73.884 -53.937 73.103 1.00 99.44 ? 254 ARG B N 1 ATOM 6134 C CA . ARG B 1 254 ? -74.732 -53.717 74.289 1.00 100.62 ? 254 ARG B CA 1 ATOM 6135 C C . ARG B 1 254 ? -76.206 -53.405 73.981 1.00 101.57 ? 254 ARG B C 1 ATOM 6136 O O . ARG B 1 254 ? -76.646 -53.460 72.829 1.00 101.65 ? 254 ARG B O 1 ATOM 6137 C CB . ARG B 1 254 ? -74.128 -52.600 75.161 1.00 100.44 ? 254 ARG B CB 1 ATOM 6138 C CG . ARG B 1 254 ? -73.896 -52.960 76.620 1.00 99.62 ? 254 ARG B CG 1 ATOM 6139 C CD . ARG B 1 254 ? -73.151 -54.283 76.733 1.00 97.76 ? 254 ARG B CD 1 ATOM 6140 N NE . ARG B 1 254 ? -72.053 -54.201 77.685 1.00 96.28 ? 254 ARG B NE 1 ATOM 6141 C CZ . ARG B 1 254 ? -70.818 -54.637 77.459 1.00 95.02 ? 254 ARG B CZ 1 ATOM 6142 N NH1 . ARG B 1 254 ? -69.897 -54.500 78.400 1.00 94.97 ? 254 ARG B NH1 1 ATOM 6143 N NH2 . ARG B 1 254 ? -70.505 -55.218 76.310 1.00 93.81 ? 254 ARG B NH2 1 ATOM 6144 N N . GLU B 1 255 ? -76.963 -53.107 75.034 1.00 102.77 ? 255 GLU B N 1 ATOM 6145 C CA . GLU B 1 255 ? -78.351 -52.686 74.908 1.00 103.95 ? 255 GLU B CA 1 ATOM 6146 C C . GLU B 1 255 ? -78.421 -51.203 75.237 1.00 104.07 ? 255 GLU B C 1 ATOM 6147 O O . GLU B 1 255 ? -78.698 -50.393 74.362 1.00 104.34 ? 255 GLU B O 1 ATOM 6148 C CB . GLU B 1 255 ? -79.279 -53.498 75.830 1.00 104.39 ? 255 GLU B CB 1 ATOM 6149 C CG . GLU B 1 255 ? -80.742 -52.987 75.903 1.00 106.28 ? 255 GLU B CG 1 ATOM 6150 C CD . GLU B 1 255 ? -81.755 -53.895 75.197 1.00 108.55 ? 255 GLU B CD 1 ATOM 6151 O OE1 . GLU B 1 255 ? -81.359 -54.958 74.670 1.00 109.37 ? 255 GLU B OE1 1 ATOM 6152 O OE2 . GLU B 1 255 ? -82.958 -53.546 75.182 1.00 109.43 ? 255 GLU B OE2 1 ATOM 6153 N N . ASN B 1 256 ? -78.166 -50.835 76.488 1.00 104.26 ? 256 ASN B N 1 ATOM 6154 C CA . ASN B 1 256 ? -78.106 -49.423 76.815 1.00 104.39 ? 256 ASN B CA 1 ATOM 6155 C C . ASN B 1 256 ? -76.907 -48.868 76.060 1.00 104.50 ? 256 ASN B C 1 ATOM 6156 O O . ASN B 1 256 ? -75.779 -49.337 76.230 1.00 104.67 ? 256 ASN B O 1 ATOM 6157 C CB . ASN B 1 256 ? -77.988 -49.194 78.328 1.00 104.47 ? 256 ASN B CB 1 ATOM 6158 C CG . ASN B 1 256 ? -78.491 -47.809 78.766 1.00 104.32 ? 256 ASN B CG 1 ATOM 6159 O OD1 . ASN B 1 256 ? -77.691 -46.925 79.093 1.00 103.86 ? 256 ASN B OD1 1 ATOM 6160 N ND2 . ASN B 1 256 ? -79.820 -47.625 78.788 1.00 103.87 ? 256 ASN B ND2 1 ATOM 6161 N N . GLU B 1 257 ? -77.175 -47.917 75.173 1.00 104.45 ? 257 GLU B N 1 ATOM 6162 C CA . GLU B 1 257 ? -76.134 -47.314 74.363 1.00 104.34 ? 257 GLU B CA 1 ATOM 6163 C C . GLU B 1 257 ? -75.029 -46.742 75.228 1.00 103.97 ? 257 GLU B C 1 ATOM 6164 O O . GLU B 1 257 ? -73.853 -47.019 75.004 1.00 104.05 ? 257 GLU B O 1 ATOM 6165 C CB . GLU B 1 257 ? -76.719 -46.206 73.493 1.00 104.67 ? 257 GLU B CB 1 ATOM 6166 C CG . GLU B 1 257 ? -77.340 -46.690 72.185 1.00 105.24 ? 257 GLU B CG 1 ATOM 6167 C CD . GLU B 1 257 ? -77.299 -45.620 71.097 1.00 105.44 ? 257 GLU B CD 1 ATOM 6168 O OE1 . GLU B 1 257 ? -76.968 -44.449 71.418 1.00 104.67 ? 257 GLU B OE1 1 ATOM 6169 O OE2 . GLU B 1 257 ? -77.590 -45.958 69.925 1.00 105.73 ? 257 GLU B OE2 1 ATOM 6170 N N . THR B 1 258 ? -75.418 -45.939 76.214 1.00 103.56 ? 258 THR B N 1 ATOM 6171 C CA . THR B 1 258 ? -74.463 -45.335 77.144 1.00 103.08 ? 258 THR B CA 1 ATOM 6172 C C . THR B 1 258 ? -73.503 -46.390 77.691 1.00 102.75 ? 258 THR B C 1 ATOM 6173 O O . THR B 1 258 ? -72.320 -46.114 77.912 1.00 102.70 ? 258 THR B O 1 ATOM 6174 C CB . THR B 1 258 ? -75.179 -44.614 78.310 1.00 103.10 ? 258 THR B CB 1 ATOM 6175 O OG1 . THR B 1 258 ? -76.171 -43.728 77.783 1.00 103.13 ? 258 THR B OG1 1 ATOM 6176 C CG2 . THR B 1 258 ? -74.190 -43.797 79.151 1.00 103.01 ? 258 THR B CG2 1 ATOM 6177 N N . GLU B 1 259 ? -74.009 -47.603 77.898 1.00 102.22 ? 259 GLU B N 1 ATOM 6178 C CA . GLU B 1 259 ? -73.168 -48.697 78.368 1.00 101.68 ? 259 GLU B CA 1 ATOM 6179 C C . GLU B 1 259 ? -72.032 -49.016 77.395 1.00 100.87 ? 259 GLU B C 1 ATOM 6180 O O . GLU B 1 259 ? -70.903 -49.246 77.817 1.00 100.83 ? 259 GLU B O 1 ATOM 6181 C CB . GLU B 1 259 ? -74.009 -49.939 78.686 1.00 102.07 ? 259 GLU B CB 1 ATOM 6182 C CG . GLU B 1 259 ? -74.681 -49.874 80.077 1.00 103.00 ? 259 GLU B CG 1 ATOM 6183 C CD . GLU B 1 259 ? -75.460 -51.137 80.418 1.00 104.32 ? 259 GLU B CD 1 ATOM 6184 O OE1 . GLU B 1 259 ? -76.635 -51.023 80.844 1.00 104.81 ? 259 GLU B OE1 1 ATOM 6185 O OE2 . GLU B 1 259 ? -74.898 -52.244 80.245 1.00 104.60 ? 259 GLU B OE2 1 ATOM 6186 N N . ILE B 1 260 ? -72.317 -49.004 76.096 1.00 99.90 ? 260 ILE B N 1 ATOM 6187 C CA . ILE B 1 260 ? -71.262 -49.204 75.108 1.00 98.77 ? 260 ILE B CA 1 ATOM 6188 C C . ILE B 1 260 ? -70.154 -48.179 75.272 1.00 98.16 ? 260 ILE B C 1 ATOM 6189 O O . ILE B 1 260 ? -68.991 -48.465 75.024 1.00 98.00 ? 260 ILE B O 1 ATOM 6190 C CB . ILE B 1 260 ? -71.756 -49.068 73.672 1.00 98.59 ? 260 ILE B CB 1 ATOM 6191 C CG1 . ILE B 1 260 ? -73.101 -49.766 73.486 1.00 98.40 ? 260 ILE B CG1 1 ATOM 6192 C CG2 . ILE B 1 260 ? -70.698 -49.620 72.720 1.00 98.69 ? 260 ILE B CG2 1 ATOM 6193 C CD1 . ILE B 1 260 ? -73.399 -50.140 72.051 1.00 98.09 ? 260 ILE B CD1 1 ATOM 6194 N N . ILE B 1 261 ? -70.516 -46.966 75.657 1.00 97.53 ? 261 ILE B N 1 ATOM 6195 C CA . ILE B 1 261 ? -69.498 -45.961 75.914 1.00 97.18 ? 261 ILE B CA 1 ATOM 6196 C C . ILE B 1 261 ? -68.753 -46.304 77.206 1.00 96.94 ? 261 ILE B C 1 ATOM 6197 O O . ILE B 1 261 ? -67.519 -46.239 77.261 1.00 96.97 ? 261 ILE B O 1 ATOM 6198 C CB . ILE B 1 261 ? -70.086 -44.540 76.001 1.00 97.18 ? 261 ILE B CB 1 ATOM 6199 C CG1 . ILE B 1 261 ? -70.911 -44.231 74.757 1.00 97.12 ? 261 ILE B CG1 1 ATOM 6200 C CG2 . ILE B 1 261 ? -68.977 -43.512 76.135 1.00 97.07 ? 261 ILE B CG2 1 ATOM 6201 C CD1 . ILE B 1 261 ? -70.184 -44.539 73.476 1.00 96.98 ? 261 ILE B CD1 1 ATOM 6202 N N . LYS B 1 262 ? -69.510 -46.676 78.240 1.00 96.39 ? 262 LYS B N 1 ATOM 6203 C CA . LYS B 1 262 ? -68.937 -47.159 79.495 1.00 95.83 ? 262 LYS B CA 1 ATOM 6204 C C . LYS B 1 262 ? -67.902 -48.260 79.229 1.00 95.17 ? 262 LYS B C 1 ATOM 6205 O O . LYS B 1 262 ? -66.760 -48.160 79.669 1.00 95.10 ? 262 LYS B O 1 ATOM 6206 C CB . LYS B 1 262 ? -70.041 -47.695 80.413 1.00 96.07 ? 262 LYS B CB 1 ATOM 6207 C CG . LYS B 1 262 ? -69.699 -47.692 81.910 1.00 96.87 ? 262 LYS B CG 1 ATOM 6208 C CD . LYS B 1 262 ? -69.995 -46.327 82.532 1.00 98.12 ? 262 LYS B CD 1 ATOM 6209 C CE . LYS B 1 262 ? -70.016 -46.385 84.048 1.00 98.36 ? 262 LYS B CE 1 ATOM 6210 N NZ . LYS B 1 262 ? -68.667 -46.708 84.585 1.00 99.09 ? 262 LYS B NZ 1 ATOM 6211 N N . CYS B 1 263 ? -68.314 -49.307 78.514 1.00 94.29 ? 263 CYS B N 1 ATOM 6212 C CA . CYS B 1 263 ? -67.413 -50.361 78.045 1.00 93.65 ? 263 CYS B CA 1 ATOM 6213 C C . CYS B 1 263 ? -66.121 -49.810 77.471 1.00 93.00 ? 263 CYS B C 1 ATOM 6214 O O . CYS B 1 263 ? -65.032 -50.111 77.948 1.00 92.99 ? 263 CYS B O 1 ATOM 6215 C CB . CYS B 1 263 ? -68.087 -51.150 76.923 1.00 93.85 ? 263 CYS B CB 1 ATOM 6216 S SG . CYS B 1 263 ? -67.194 -52.638 76.430 1.00 95.23 ? 263 CYS B SG 1 ATOM 6217 N N . LEU B 1 264 ? -66.269 -49.007 76.419 1.00 92.31 ? 264 LEU B N 1 ATOM 6218 C CA . LEU B 1 264 ? -65.159 -48.536 75.601 1.00 91.32 ? 264 LEU B CA 1 ATOM 6219 C C . LEU B 1 264 ? -64.295 -47.582 76.381 1.00 90.96 ? 264 LEU B C 1 ATOM 6220 O O . LEU B 1 264 ? -63.079 -47.530 76.187 1.00 90.78 ? 264 LEU B O 1 ATOM 6221 C CB . LEU B 1 264 ? -65.688 -47.826 74.355 1.00 91.21 ? 264 LEU B CB 1 ATOM 6222 C CG . LEU B 1 264 ? -66.220 -48.711 73.230 1.00 90.79 ? 264 LEU B CG 1 ATOM 6223 C CD1 . LEU B 1 264 ? -67.055 -47.907 72.264 1.00 90.44 ? 264 LEU B CD1 1 ATOM 6224 C CD2 . LEU B 1 264 ? -65.071 -49.392 72.519 1.00 91.20 ? 264 LEU B CD2 1 ATOM 6225 N N . ARG B 1 265 ? -64.935 -46.807 77.251 1.00 90.54 ? 265 ARG B N 1 ATOM 6226 C CA . ARG B 1 265 ? -64.209 -45.904 78.126 1.00 90.32 ? 265 ARG B CA 1 ATOM 6227 C C . ARG B 1 265 ? -63.159 -46.648 78.951 1.00 89.83 ? 265 ARG B C 1 ATOM 6228 O O . ARG B 1 265 ? -62.284 -46.021 79.548 1.00 89.80 ? 265 ARG B O 1 ATOM 6229 C CB . ARG B 1 265 ? -65.167 -45.182 79.063 1.00 90.48 ? 265 ARG B CB 1 ATOM 6230 C CG . ARG B 1 265 ? -65.751 -43.919 78.498 1.00 91.63 ? 265 ARG B CG 1 ATOM 6231 C CD . ARG B 1 265 ? -65.943 -42.914 79.614 1.00 94.51 ? 265 ARG B CD 1 ATOM 6232 N NE . ARG B 1 265 ? -66.610 -41.712 79.135 1.00 96.52 ? 265 ARG B NE 1 ATOM 6233 C CZ . ARG B 1 265 ? -67.928 -41.583 79.068 1.00 97.08 ? 265 ARG B CZ 1 ATOM 6234 N NH1 . ARG B 1 265 ? -68.472 -40.449 78.623 1.00 96.73 ? 265 ARG B NH1 1 ATOM 6235 N NH2 . ARG B 1 265 ? -68.696 -42.596 79.455 1.00 97.09 ? 265 ARG B NH2 1 ATOM 6236 N N . ASN B 1 266 ? -63.251 -47.981 78.975 1.00 89.16 ? 266 ASN B N 1 ATOM 6237 C CA . ASN B 1 266 ? -62.385 -48.804 79.834 1.00 88.57 ? 266 ASN B CA 1 ATOM 6238 C C . ASN B 1 266 ? -61.334 -49.635 79.111 1.00 87.85 ? 266 ASN B C 1 ATOM 6239 O O . ASN B 1 266 ? -60.404 -50.116 79.737 1.00 88.07 ? 266 ASN B O 1 ATOM 6240 C CB . ASN B 1 266 ? -63.208 -49.687 80.801 1.00 88.75 ? 266 ASN B CB 1 ATOM 6241 C CG . ASN B 1 266 ? -63.601 -48.938 82.100 1.00 89.92 ? 266 ASN B CG 1 ATOM 6242 O OD1 . ASN B 1 266 ? -62.740 -48.568 82.910 1.00 90.33 ? 266 ASN B OD1 1 ATOM 6243 N ND2 . ASN B 1 266 ? -64.906 -48.705 82.287 1.00 91.04 ? 266 ASN B ND2 1 ATOM 6244 N N . LYS B 1 267 ? -61.470 -49.808 77.804 1.00 86.93 ? 267 LYS B N 1 ATOM 6245 C CA . LYS B 1 267 ? -60.439 -50.489 77.054 1.00 85.94 ? 267 LYS B CA 1 ATOM 6246 C C . LYS B 1 267 ? -59.197 -49.611 76.983 1.00 85.42 ? 267 LYS B C 1 ATOM 6247 O O . LYS B 1 267 ? -59.250 -48.410 77.250 1.00 84.84 ? 267 LYS B O 1 ATOM 6248 C CB . LYS B 1 267 ? -60.937 -50.801 75.650 1.00 86.11 ? 267 LYS B CB 1 ATOM 6249 C CG . LYS B 1 267 ? -62.208 -51.645 75.584 1.00 86.65 ? 267 LYS B CG 1 ATOM 6250 C CD . LYS B 1 267 ? -61.944 -53.023 74.962 1.00 87.42 ? 267 LYS B CD 1 ATOM 6251 C CE . LYS B 1 267 ? -61.634 -54.091 76.014 1.00 87.46 ? 267 LYS B CE 1 ATOM 6252 N NZ . LYS B 1 267 ? -62.868 -54.587 76.665 1.00 87.26 ? 267 LYS B NZ 1 ATOM 6253 N N . ASP B 1 268 ? -58.075 -50.224 76.611 1.00 85.35 ? 268 ASP B N 1 ATOM 6254 C CA A ASP B 1 268 ? -56.821 -49.497 76.472 0.50 85.14 ? 268 ASP B CA 1 ATOM 6255 C CA B ASP B 1 268 ? -56.792 -49.516 76.460 0.50 85.16 ? 268 ASP B CA 1 ATOM 6256 C C . ASP B 1 268 ? -56.730 -48.784 75.130 1.00 84.99 ? 268 ASP B C 1 ATOM 6257 O O . ASP B 1 268 ? -57.030 -49.363 74.086 1.00 84.68 ? 268 ASP B O 1 ATOM 6258 C CB A ASP B 1 268 ? -55.620 -50.427 76.687 0.50 85.12 ? 268 ASP B CB 1 ATOM 6259 C CB B ASP B 1 268 ? -55.602 -50.496 76.589 0.50 85.14 ? 268 ASP B CB 1 ATOM 6260 C CG A ASP B 1 268 ? -55.210 -50.510 78.148 0.50 85.00 ? 268 ASP B CG 1 ATOM 6261 C CG B ASP B 1 268 ? -54.321 -49.997 75.895 0.50 85.13 ? 268 ASP B CG 1 ATOM 6262 O OD1 A ASP B 1 268 ? -54.460 -51.437 78.517 0.50 84.80 ? 268 ASP B OD1 1 ATOM 6263 O OD1 B ASP B 1 268 ? -53.786 -48.925 76.257 0.50 85.05 ? 268 ASP B OD1 1 ATOM 6264 O OD2 A ASP B 1 268 ? -55.644 -49.640 78.933 0.50 85.14 ? 268 ASP B OD2 1 ATOM 6265 O OD2 B ASP B 1 268 ? -53.821 -50.705 74.997 0.50 84.97 ? 268 ASP B OD2 1 ATOM 6266 N N . PRO B 1 269 ? -56.332 -47.507 75.166 1.00 84.90 ? 269 PRO B N 1 ATOM 6267 C CA . PRO B 1 269 ? -56.082 -46.732 73.984 1.00 85.02 ? 269 PRO B CA 1 ATOM 6268 C C . PRO B 1 269 ? -55.635 -47.622 72.844 1.00 85.33 ? 269 PRO B C 1 ATOM 6269 O O . PRO B 1 269 ? -56.232 -47.625 71.773 1.00 85.48 ? 269 PRO B O 1 ATOM 6270 C CB . PRO B 1 269 ? -54.918 -45.849 74.415 1.00 84.77 ? 269 PRO B CB 1 ATOM 6271 C CG . PRO B 1 269 ? -55.118 -45.665 75.882 1.00 84.85 ? 269 PRO B CG 1 ATOM 6272 C CD . PRO B 1 269 ? -56.089 -46.708 76.371 1.00 84.91 ? 269 PRO B CD 1 ATOM 6273 N N . GLN B 1 270 ? -54.585 -48.382 73.072 1.00 85.71 ? 270 GLN B N 1 ATOM 6274 C CA . GLN B 1 270 ? -54.045 -49.200 72.014 1.00 86.29 ? 270 GLN B CA 1 ATOM 6275 C C . GLN B 1 270 ? -55.024 -50.201 71.416 1.00 86.01 ? 270 GLN B C 1 ATOM 6276 O O . GLN B 1 270 ? -55.001 -50.493 70.211 1.00 85.87 ? 270 GLN B O 1 ATOM 6277 C CB . GLN B 1 270 ? -52.765 -49.855 72.468 1.00 86.69 ? 270 GLN B CB 1 ATOM 6278 C CG . GLN B 1 270 ? -51.730 -49.162 71.775 1.00 89.27 ? 270 GLN B CG 1 ATOM 6279 C CD . GLN B 1 270 ? -50.983 -48.301 72.640 1.00 92.11 ? 270 GLN B CD 1 ATOM 6280 O OE1 . GLN B 1 270 ? -50.162 -48.832 73.326 1.00 93.27 ? 270 GLN B OE1 1 ATOM 6281 N NE2 . GLN B 1 270 ? -51.185 -46.968 72.606 1.00 92.08 ? 270 GLN B NE2 1 ATOM 6282 N N . GLU B 1 271 ? -55.887 -50.737 72.264 1.00 86.01 ? 271 GLU B N 1 ATOM 6283 C CA . GLU B 1 271 ? -56.856 -51.734 71.814 1.00 85.99 ? 271 GLU B CA 1 ATOM 6284 C C . GLU B 1 271 ? -57.842 -51.106 70.830 1.00 85.43 ? 271 GLU B C 1 ATOM 6285 O O . GLU B 1 271 ? -58.311 -51.761 69.896 1.00 85.23 ? 271 GLU B O 1 ATOM 6286 C CB . GLU B 1 271 ? -57.600 -52.320 73.014 1.00 86.25 ? 271 GLU B CB 1 ATOM 6287 C CG . GLU B 1 271 ? -58.114 -53.727 72.797 1.00 87.53 ? 271 GLU B CG 1 ATOM 6288 C CD . GLU B 1 271 ? -58.817 -54.275 74.020 1.00 89.41 ? 271 GLU B CD 1 ATOM 6289 O OE1 . GLU B 1 271 ? -58.383 -53.990 75.165 1.00 89.33 ? 271 GLU B OE1 1 ATOM 6290 O OE2 . GLU B 1 271 ? -59.813 -54.997 73.825 1.00 90.29 ? 271 GLU B OE2 1 ATOM 6291 N N . ILE B 1 272 ? -58.156 -49.831 71.072 1.00 84.84 ? 272 ILE B N 1 ATOM 6292 C CA . ILE B 1 272 ? -59.042 -49.046 70.223 1.00 83.96 ? 272 ILE B CA 1 ATOM 6293 C C . ILE B 1 272 ? -58.313 -48.687 68.953 1.00 83.86 ? 272 ILE B C 1 ATOM 6294 O O . ILE B 1 272 ? -58.783 -48.970 67.867 1.00 83.90 ? 272 ILE B O 1 ATOM 6295 C CB . ILE B 1 272 ? -59.473 -47.751 70.916 1.00 83.69 ? 272 ILE B CB 1 ATOM 6296 C CG1 . ILE B 1 272 ? -60.679 -48.002 71.828 1.00 83.30 ? 272 ILE B CG1 1 ATOM 6297 C CG2 . ILE B 1 272 ? -59.797 -46.719 69.883 1.00 83.42 ? 272 ILE B CG2 1 ATOM 6298 C CD1 . ILE B 1 272 ? -60.811 -47.024 72.965 1.00 82.36 ? 272 ILE B CD1 1 ATOM 6299 N N . LEU B 1 273 ? -57.143 -48.083 69.092 1.00 83.76 ? 273 LEU B N 1 ATOM 6300 C CA . LEU B 1 273 ? -56.344 -47.720 67.942 1.00 83.80 ? 273 LEU B CA 1 ATOM 6301 C C . LEU B 1 273 ? -56.185 -48.877 66.985 1.00 84.11 ? 273 LEU B C 1 ATOM 6302 O O . LEU B 1 273 ? -56.054 -48.688 65.785 1.00 84.07 ? 273 LEU B O 1 ATOM 6303 C CB . LEU B 1 273 ? -54.970 -47.239 68.384 1.00 83.54 ? 273 LEU B CB 1 ATOM 6304 C CG . LEU B 1 273 ? -54.983 -45.825 68.932 1.00 83.58 ? 273 LEU B CG 1 ATOM 6305 C CD1 . LEU B 1 273 ? -53.630 -45.496 69.514 1.00 84.78 ? 273 LEU B CD1 1 ATOM 6306 C CD2 . LEU B 1 273 ? -55.339 -44.858 67.833 1.00 84.09 ? 273 LEU B CD2 1 ATOM 6307 N N . LEU B 1 274 ? -56.198 -50.086 67.512 1.00 84.85 ? 274 LEU B N 1 ATOM 6308 C CA . LEU B 1 274 ? -55.886 -51.222 66.677 1.00 85.84 ? 274 LEU B CA 1 ATOM 6309 C C . LEU B 1 274 ? -57.036 -51.546 65.733 1.00 86.29 ? 274 LEU B C 1 ATOM 6310 O O . LEU B 1 274 ? -56.845 -51.745 64.527 1.00 86.50 ? 274 LEU B O 1 ATOM 6311 C CB . LEU B 1 274 ? -55.554 -52.440 67.530 1.00 86.00 ? 274 LEU B CB 1 ATOM 6312 C CG . LEU B 1 274 ? -54.705 -53.382 66.678 1.00 86.52 ? 274 LEU B CG 1 ATOM 6313 C CD1 . LEU B 1 274 ? -53.263 -52.935 66.784 1.00 86.97 ? 274 LEU B CD1 1 ATOM 6314 C CD2 . LEU B 1 274 ? -54.877 -54.841 67.057 1.00 86.44 ? 274 LEU B CD2 1 ATOM 6315 N N . ASN B 1 275 ? -58.231 -51.599 66.303 1.00 86.75 ? 275 ASN B N 1 ATOM 6316 C CA . ASN B 1 275 ? -59.428 -51.947 65.561 1.00 87.33 ? 275 ASN B CA 1 ATOM 6317 C C . ASN B 1 275 ? -59.943 -50.856 64.623 1.00 87.70 ? 275 ASN B C 1 ATOM 6318 O O . ASN B 1 275 ? -60.639 -51.156 63.651 1.00 87.70 ? 275 ASN B O 1 ATOM 6319 C CB . ASN B 1 275 ? -60.536 -52.320 66.533 1.00 87.40 ? 275 ASN B CB 1 ATOM 6320 C CG . ASN B 1 275 ? -60.245 -53.587 67.272 1.00 87.56 ? 275 ASN B CG 1 ATOM 6321 O OD1 . ASN B 1 275 ? -60.063 -53.577 68.488 1.00 88.42 ? 275 ASN B OD1 1 ATOM 6322 N ND2 . ASN B 1 275 ? -60.195 -54.696 66.547 1.00 87.88 ? 275 ASN B ND2 1 ATOM 6323 N N . GLU B 1 276 ? -59.619 -49.597 64.927 1.00 88.05 ? 276 GLU B N 1 ATOM 6324 C CA . GLU B 1 276 ? -60.013 -48.467 64.087 1.00 88.27 ? 276 GLU B CA 1 ATOM 6325 C C . GLU B 1 276 ? -59.896 -48.824 62.619 1.00 88.57 ? 276 GLU B C 1 ATOM 6326 O O . GLU B 1 276 ? -60.830 -48.642 61.846 1.00 88.58 ? 276 GLU B O 1 ATOM 6327 C CB . GLU B 1 276 ? -59.128 -47.248 64.357 1.00 88.28 ? 276 GLU B CB 1 ATOM 6328 C CG . GLU B 1 276 ? -59.481 -46.444 65.604 1.00 88.21 ? 276 GLU B CG 1 ATOM 6329 C CD . GLU B 1 276 ? -58.743 -45.105 65.666 1.00 88.53 ? 276 GLU B CD 1 ATOM 6330 O OE1 . GLU B 1 276 ? -58.022 -44.770 64.695 1.00 88.73 ? 276 GLU B OE1 1 ATOM 6331 O OE2 . GLU B 1 276 ? -58.885 -44.385 66.682 1.00 88.19 ? 276 GLU B OE2 1 ATOM 6332 N N . ALA B 1 277 ? -58.738 -49.333 62.233 1.00 88.94 ? 277 ALA B N 1 ATOM 6333 C CA . ALA B 1 277 ? -58.522 -49.667 60.847 1.00 89.46 ? 277 ALA B CA 1 ATOM 6334 C C . ALA B 1 277 ? -59.651 -50.530 60.285 1.00 89.89 ? 277 ALA B C 1 ATOM 6335 O O . ALA B 1 277 ? -59.925 -50.491 59.098 1.00 90.10 ? 277 ALA B O 1 ATOM 6336 C CB . ALA B 1 277 ? -57.186 -50.351 60.681 1.00 89.42 ? 277 ALA B CB 1 ATOM 6337 N N . PHE B 1 278 ? -60.337 -51.281 61.137 1.00 90.51 ? 278 PHE B N 1 ATOM 6338 C CA . PHE B 1 278 ? -61.223 -52.347 60.646 1.00 91.11 ? 278 PHE B CA 1 ATOM 6339 C C . PHE B 1 278 ? -62.735 -52.081 60.642 1.00 91.25 ? 278 PHE B C 1 ATOM 6340 O O . PHE B 1 278 ? -63.507 -52.962 60.246 1.00 91.35 ? 278 PHE B O 1 ATOM 6341 C CB . PHE B 1 278 ? -60.956 -53.652 61.404 1.00 91.16 ? 278 PHE B CB 1 ATOM 6342 C CG . PHE B 1 278 ? -59.528 -54.092 61.357 1.00 92.30 ? 278 PHE B CG 1 ATOM 6343 C CD1 . PHE B 1 278 ? -58.761 -54.148 62.526 1.00 93.21 ? 278 PHE B CD1 1 ATOM 6344 C CD2 . PHE B 1 278 ? -58.935 -54.439 60.141 1.00 93.12 ? 278 PHE B CD2 1 ATOM 6345 C CE1 . PHE B 1 278 ? -57.417 -54.554 62.486 1.00 93.60 ? 278 PHE B CE1 1 ATOM 6346 C CE2 . PHE B 1 278 ? -57.598 -54.846 60.078 1.00 93.54 ? 278 PHE B CE2 1 ATOM 6347 C CZ . PHE B 1 278 ? -56.833 -54.906 61.252 1.00 93.92 ? 278 PHE B CZ 1 ATOM 6348 N N . VAL B 1 279 ? -63.174 -50.902 61.076 1.00 91.29 ? 279 VAL B N 1 ATOM 6349 C CA . VAL B 1 279 ? -64.611 -50.694 61.245 1.00 91.33 ? 279 VAL B CA 1 ATOM 6350 C C . VAL B 1 279 ? -65.336 -50.498 59.931 1.00 91.56 ? 279 VAL B C 1 ATOM 6351 O O . VAL B 1 279 ? -66.554 -50.419 59.915 1.00 91.90 ? 279 VAL B O 1 ATOM 6352 C CB . VAL B 1 279 ? -64.952 -49.524 62.180 1.00 91.19 ? 279 VAL B CB 1 ATOM 6353 C CG1 . VAL B 1 279 ? -64.635 -49.884 63.606 1.00 91.12 ? 279 VAL B CG1 1 ATOM 6354 C CG2 . VAL B 1 279 ? -64.209 -48.286 61.759 1.00 91.51 ? 279 VAL B CG2 1 ATOM 6355 N N . VAL B 1 280 ? -64.608 -50.423 58.828 1.00 91.82 ? 280 VAL B N 1 ATOM 6356 C CA . VAL B 1 280 ? -65.271 -50.353 57.542 1.00 92.14 ? 280 VAL B CA 1 ATOM 6357 C C . VAL B 1 280 ? -65.094 -51.675 56.797 1.00 92.81 ? 280 VAL B C 1 ATOM 6358 O O . VAL B 1 280 ? -64.140 -52.408 57.055 1.00 92.80 ? 280 VAL B O 1 ATOM 6359 C CB . VAL B 1 280 ? -64.732 -49.194 56.707 1.00 91.99 ? 280 VAL B CB 1 ATOM 6360 C CG1 . VAL B 1 280 ? -64.714 -47.938 57.538 1.00 91.57 ? 280 VAL B CG1 1 ATOM 6361 C CG2 . VAL B 1 280 ? -63.350 -49.524 56.187 1.00 91.78 ? 280 VAL B CG2 1 ATOM 6362 N N . PRO B 1 281 ? -66.020 -51.987 55.868 1.00 93.38 ? 281 PRO B N 1 ATOM 6363 C CA . PRO B 1 281 ? -65.958 -53.215 55.069 1.00 93.40 ? 281 PRO B CA 1 ATOM 6364 C C . PRO B 1 281 ? -64.678 -53.268 54.246 1.00 93.40 ? 281 PRO B C 1 ATOM 6365 O O . PRO B 1 281 ? -63.913 -54.215 54.366 1.00 93.74 ? 281 PRO B O 1 ATOM 6366 C CB . PRO B 1 281 ? -67.187 -53.105 54.153 1.00 93.56 ? 281 PRO B CB 1 ATOM 6367 C CG . PRO B 1 281 ? -67.508 -51.626 54.107 1.00 93.62 ? 281 PRO B CG 1 ATOM 6368 C CD . PRO B 1 281 ? -67.174 -51.146 55.492 1.00 93.68 ? 281 PRO B CD 1 ATOM 6369 N N . TYR B 1 282 ? -64.435 -52.265 53.416 1.00 93.21 ? 282 TYR B N 1 ATOM 6370 C CA . TYR B 1 282 ? -63.131 -52.153 52.783 1.00 93.04 ? 282 TYR B CA 1 ATOM 6371 C C . TYR B 1 282 ? -62.646 -50.710 52.907 1.00 92.01 ? 282 TYR B C 1 ATOM 6372 O O . TYR B 1 282 ? -63.448 -49.788 53.081 1.00 92.33 ? 282 TYR B O 1 ATOM 6373 C CB . TYR B 1 282 ? -63.168 -52.639 51.329 1.00 93.53 ? 282 TYR B CB 1 ATOM 6374 C CG . TYR B 1 282 ? -61.782 -52.926 50.738 1.00 97.15 ? 282 TYR B CG 1 ATOM 6375 C CD1 . TYR B 1 282 ? -61.524 -52.722 49.374 1.00 99.65 ? 282 TYR B CD1 1 ATOM 6376 C CD2 . TYR B 1 282 ? -60.721 -53.385 51.544 1.00 99.96 ? 282 TYR B CD2 1 ATOM 6377 C CE1 . TYR B 1 282 ? -60.250 -52.979 48.811 1.00 101.26 ? 282 TYR B CE1 1 ATOM 6378 C CE2 . TYR B 1 282 ? -59.432 -53.644 50.994 1.00 101.35 ? 282 TYR B CE2 1 ATOM 6379 C CZ . TYR B 1 282 ? -59.204 -53.435 49.617 1.00 102.27 ? 282 TYR B CZ 1 ATOM 6380 O OH . TYR B 1 282 ? -57.954 -53.671 49.035 1.00 101.96 ? 282 TYR B OH 1 ATOM 6381 N N . GLY B 1 283 ? -61.335 -50.514 52.852 1.00 90.58 ? 283 GLY B N 1 ATOM 6382 C CA . GLY B 1 283 ? -60.790 -49.173 52.984 1.00 88.63 ? 283 GLY B CA 1 ATOM 6383 C C . GLY B 1 283 ? -59.956 -48.707 51.805 1.00 87.18 ? 283 GLY B C 1 ATOM 6384 O O . GLY B 1 283 ? -59.749 -49.441 50.833 1.00 87.22 ? 283 GLY B O 1 ATOM 6385 N N . THR B 1 284 ? -59.488 -47.467 51.884 1.00 85.45 ? 284 THR B N 1 ATOM 6386 C CA . THR B 1 284 ? -58.580 -46.937 50.888 1.00 83.61 ? 284 THR B CA 1 ATOM 6387 C C . THR B 1 284 ? -57.460 -46.277 51.624 1.00 82.26 ? 284 THR B C 1 ATOM 6388 O O . THR B 1 284 ? -57.595 -45.955 52.798 1.00 82.16 ? 284 THR B O 1 ATOM 6389 C CB . THR B 1 284 ? -59.236 -45.860 50.031 1.00 83.57 ? 284 THR B CB 1 ATOM 6390 O OG1 . THR B 1 284 ? -59.809 -44.861 50.883 1.00 83.59 ? 284 THR B OG1 1 ATOM 6391 C CG2 . THR B 1 284 ? -60.315 -46.465 49.158 1.00 83.56 ? 284 THR B CG2 1 ATOM 6392 N N . PRO B 1 285 ? -56.346 -46.066 50.933 1.00 81.00 ? 285 PRO B N 1 ATOM 6393 C CA . PRO B 1 285 ? -55.227 -45.292 51.454 1.00 80.12 ? 285 PRO B CA 1 ATOM 6394 C C . PRO B 1 285 ? -55.690 -43.969 52.065 1.00 79.28 ? 285 PRO B C 1 ATOM 6395 O O . PRO B 1 285 ? -54.938 -43.354 52.824 1.00 79.50 ? 285 PRO B O 1 ATOM 6396 C CB . PRO B 1 285 ? -54.388 -45.012 50.213 1.00 80.10 ? 285 PRO B CB 1 ATOM 6397 C CG . PRO B 1 285 ? -54.691 -46.154 49.291 1.00 80.60 ? 285 PRO B CG 1 ATOM 6398 C CD . PRO B 1 285 ? -56.085 -46.623 49.598 1.00 80.89 ? 285 PRO B CD 1 ATOM 6399 N N . LEU B 1 286 ? -56.915 -43.549 51.740 1.00 78.07 ? 286 LEU B N 1 ATOM 6400 C CA . LEU B 1 286 ? -57.459 -42.261 52.175 1.00 76.47 ? 286 LEU B CA 1 ATOM 6401 C C . LEU B 1 286 ? -58.569 -42.391 53.189 1.00 75.63 ? 286 LEU B C 1 ATOM 6402 O O . LEU B 1 286 ? -59.166 -41.389 53.575 1.00 75.50 ? 286 LEU B O 1 ATOM 6403 C CB . LEU B 1 286 ? -58.000 -41.496 50.980 1.00 76.23 ? 286 LEU B CB 1 ATOM 6404 C CG . LEU B 1 286 ? -56.908 -40.736 50.267 1.00 75.84 ? 286 LEU B CG 1 ATOM 6405 C CD1 . LEU B 1 286 ? -56.920 -41.028 48.782 1.00 76.22 ? 286 LEU B CD1 1 ATOM 6406 C CD2 . LEU B 1 286 ? -57.086 -39.267 50.548 1.00 75.81 ? 286 LEU B CD2 1 ATOM 6407 N N . SER B 1 287 ? -58.862 -43.614 53.613 1.00 74.59 ? 287 SER B N 1 ATOM 6408 C CA . SER B 1 287 ? -59.982 -43.832 54.533 1.00 73.92 ? 287 SER B CA 1 ATOM 6409 C C . SER B 1 287 ? -59.861 -42.980 55.790 1.00 72.92 ? 287 SER B C 1 ATOM 6410 O O . SER B 1 287 ? -58.909 -43.119 56.548 1.00 72.90 ? 287 SER B O 1 ATOM 6411 C CB . SER B 1 287 ? -60.100 -45.309 54.923 1.00 73.92 ? 287 SER B CB 1 ATOM 6412 O OG . SER B 1 287 ? -60.205 -46.121 53.765 1.00 74.49 ? 287 SER B OG 1 ATOM 6413 N N . VAL B 1 288 ? -60.823 -42.095 55.992 1.00 71.67 ? 288 VAL B N 1 ATOM 6414 C CA . VAL B 1 288 ? -60.887 -41.338 57.214 1.00 70.75 ? 288 VAL B CA 1 ATOM 6415 C C . VAL B 1 288 ? -61.948 -41.988 58.057 1.00 70.66 ? 288 VAL B C 1 ATOM 6416 O O . VAL B 1 288 ? -63.071 -41.527 58.082 1.00 70.96 ? 288 VAL B O 1 ATOM 6417 C CB . VAL B 1 288 ? -61.282 -39.877 56.961 1.00 70.52 ? 288 VAL B CB 1 ATOM 6418 C CG1 . VAL B 1 288 ? -61.867 -39.258 58.205 1.00 69.53 ? 288 VAL B CG1 1 ATOM 6419 C CG2 . VAL B 1 288 ? -60.091 -39.081 56.479 1.00 69.90 ? 288 VAL B CG2 1 ATOM 6420 N N . ASN B 1 289 ? -61.591 -43.059 58.750 1.00 70.34 ? 289 ASN B N 1 ATOM 6421 C CA . ASN B 1 289 ? -62.568 -43.858 59.469 1.00 70.18 ? 289 ASN B CA 1 ATOM 6422 C C . ASN B 1 289 ? -63.402 -43.119 60.503 1.00 69.71 ? 289 ASN B C 1 ATOM 6423 O O . ASN B 1 289 ? -64.604 -43.326 60.581 1.00 69.36 ? 289 ASN B O 1 ATOM 6424 C CB . ASN B 1 289 ? -61.885 -45.054 60.125 1.00 70.61 ? 289 ASN B CB 1 ATOM 6425 C CG . ASN B 1 289 ? -61.230 -45.989 59.113 1.00 71.94 ? 289 ASN B CG 1 ATOM 6426 O OD1 . ASN B 1 289 ? -61.895 -46.558 58.237 1.00 72.61 ? 289 ASN B OD1 1 ATOM 6427 N ND2 . ASN B 1 289 ? -59.918 -46.171 59.246 1.00 73.55 ? 289 ASN B ND2 1 ATOM 6428 N N . PHE B 1 290 ? -62.762 -42.287 61.321 1.00 69.64 ? 290 PHE B N 1 ATOM 6429 C CA . PHE B 1 290 ? -63.489 -41.515 62.352 1.00 69.49 ? 290 PHE B CA 1 ATOM 6430 C C . PHE B 1 290 ? -63.287 -40.032 62.166 1.00 69.03 ? 290 PHE B C 1 ATOM 6431 O O . PHE B 1 290 ? -62.257 -39.480 62.569 1.00 68.84 ? 290 PHE B O 1 ATOM 6432 C CB . PHE B 1 290 ? -63.083 -41.909 63.780 1.00 69.62 ? 290 PHE B CB 1 ATOM 6433 C CG . PHE B 1 290 ? -63.621 -43.240 64.205 1.00 69.99 ? 290 PHE B CG 1 ATOM 6434 C CD1 . PHE B 1 290 ? -64.829 -43.339 64.873 1.00 71.00 ? 290 PHE B CD1 1 ATOM 6435 C CD2 . PHE B 1 290 ? -62.937 -44.395 63.903 1.00 70.00 ? 290 PHE B CD2 1 ATOM 6436 C CE1 . PHE B 1 290 ? -65.336 -44.574 65.242 1.00 70.32 ? 290 PHE B CE1 1 ATOM 6437 C CE2 . PHE B 1 290 ? -63.444 -45.622 64.266 1.00 70.10 ? 290 PHE B CE2 1 ATOM 6438 C CZ . PHE B 1 290 ? -64.648 -45.712 64.937 1.00 69.74 ? 290 PHE B CZ 1 ATOM 6439 N N . GLY B 1 291 ? -64.273 -39.397 61.545 1.00 68.44 ? 291 GLY B N 1 ATOM 6440 C CA . GLY B 1 291 ? -64.166 -37.999 61.221 1.00 67.82 ? 291 GLY B CA 1 ATOM 6441 C C . GLY B 1 291 ? -65.339 -37.207 61.729 1.00 67.36 ? 291 GLY B C 1 ATOM 6442 O O . GLY B 1 291 ? -66.190 -37.732 62.434 1.00 67.37 ? 291 GLY B O 1 ATOM 6443 N N . PRO B 1 292 ? -65.382 -35.926 61.357 1.00 67.13 ? 292 PRO B N 1 ATOM 6444 C CA . PRO B 1 292 ? -66.453 -34.987 61.653 1.00 66.64 ? 292 PRO B CA 1 ATOM 6445 C C . PRO B 1 292 ? -67.792 -35.505 61.156 1.00 66.27 ? 292 PRO B C 1 ATOM 6446 O O . PRO B 1 292 ? -67.863 -36.123 60.094 1.00 66.12 ? 292 PRO B O 1 ATOM 6447 C CB . PRO B 1 292 ? -66.065 -33.759 60.828 1.00 66.64 ? 292 PRO B CB 1 ATOM 6448 C CG . PRO B 1 292 ? -64.578 -33.869 60.645 1.00 67.27 ? 292 PRO B CG 1 ATOM 6449 C CD . PRO B 1 292 ? -64.332 -35.332 60.506 1.00 67.35 ? 292 PRO B CD 1 ATOM 6450 N N . THR B 1 293 ? -68.850 -35.255 61.916 1.00 65.80 ? 293 THR B N 1 ATOM 6451 C CA . THR B 1 293 ? -70.183 -35.657 61.493 1.00 65.41 ? 293 THR B CA 1 ATOM 6452 C C . THR B 1 293 ? -71.200 -34.591 61.820 1.00 65.19 ? 293 THR B C 1 ATOM 6453 O O . THR B 1 293 ? -70.929 -33.661 62.581 1.00 64.68 ? 293 THR B O 1 ATOM 6454 C CB . THR B 1 293 ? -70.645 -36.934 62.190 1.00 65.30 ? 293 THR B CB 1 ATOM 6455 O OG1 . THR B 1 293 ? -70.213 -36.902 63.553 1.00 65.42 ? 293 THR B OG1 1 ATOM 6456 C CG2 . THR B 1 293 ? -70.064 -38.147 61.504 1.00 65.20 ? 293 THR B CG2 1 ATOM 6457 N N . VAL B 1 294 ? -72.387 -34.737 61.251 1.00 65.12 ? 294 VAL B N 1 ATOM 6458 C CA . VAL B 1 294 ? -73.423 -33.763 61.515 1.00 65.30 ? 294 VAL B CA 1 ATOM 6459 C C . VAL B 1 294 ? -73.965 -34.018 62.914 1.00 65.36 ? 294 VAL B C 1 ATOM 6460 O O . VAL B 1 294 ? -74.774 -34.919 63.143 1.00 65.29 ? 294 VAL B O 1 ATOM 6461 C CB . VAL B 1 294 ? -74.530 -33.792 60.456 1.00 65.10 ? 294 VAL B CB 1 ATOM 6462 C CG1 . VAL B 1 294 ? -75.415 -32.557 60.603 1.00 64.54 ? 294 VAL B CG1 1 ATOM 6463 C CG2 . VAL B 1 294 ? -73.914 -33.860 59.079 1.00 64.95 ? 294 VAL B CG2 1 ATOM 6464 N N . ASP B 1 295 ? -73.482 -33.234 63.859 1.00 65.27 ? 295 ASP B N 1 ATOM 6465 C CA . ASP B 1 295 ? -73.761 -33.550 65.231 1.00 65.48 ? 295 ASP B CA 1 ATOM 6466 C C . ASP B 1 295 ? -74.907 -32.675 65.713 1.00 65.49 ? 295 ASP B C 1 ATOM 6467 O O . ASP B 1 295 ? -75.426 -32.837 66.809 1.00 65.45 ? 295 ASP B O 1 ATOM 6468 C CB . ASP B 1 295 ? -72.502 -33.366 66.079 1.00 65.46 ? 295 ASP B CB 1 ATOM 6469 C CG . ASP B 1 295 ? -72.080 -31.910 66.190 1.00 66.02 ? 295 ASP B CG 1 ATOM 6470 O OD1 . ASP B 1 295 ? -72.459 -31.109 65.310 1.00 66.87 ? 295 ASP B OD1 1 ATOM 6471 O OD2 . ASP B 1 295 ? -71.375 -31.566 67.162 1.00 67.17 ? 295 ASP B OD2 1 ATOM 6472 N N . GLY B 1 296 ? -75.326 -31.738 64.886 1.00 65.57 ? 296 GLY B N 1 ATOM 6473 C CA . GLY B 1 296 ? -76.389 -30.848 65.332 1.00 65.85 ? 296 GLY B CA 1 ATOM 6474 C C . GLY B 1 296 ? -75.939 -29.984 66.506 1.00 65.99 ? 296 GLY B C 1 ATOM 6475 O O . GLY B 1 296 ? -76.744 -29.280 67.143 1.00 66.02 ? 296 GLY B O 1 ATOM 6476 N N . ASP B 1 297 ? -74.645 -30.043 66.805 1.00 66.04 ? 297 ASP B N 1 ATOM 6477 C CA . ASP B 1 297 ? -74.041 -29.099 67.734 1.00 66.07 ? 297 ASP B CA 1 ATOM 6478 C C . ASP B 1 297 ? -73.017 -28.219 66.977 1.00 65.80 ? 297 ASP B C 1 ATOM 6479 O O . ASP B 1 297 ? -73.305 -27.070 66.636 1.00 65.69 ? 297 ASP B O 1 ATOM 6480 C CB . ASP B 1 297 ? -73.400 -29.846 68.900 1.00 66.22 ? 297 ASP B CB 1 ATOM 6481 C CG . ASP B 1 297 ? -72.938 -28.915 70.009 1.00 67.72 ? 297 ASP B CG 1 ATOM 6482 O OD1 . ASP B 1 297 ? -73.159 -27.686 69.898 1.00 68.54 ? 297 ASP B OD1 1 ATOM 6483 O OD2 . ASP B 1 297 ? -72.353 -29.414 71.005 1.00 69.72 ? 297 ASP B OD2 1 ATOM 6484 N N . PHE B 1 298 ? -71.838 -28.768 66.693 1.00 65.49 ? 298 PHE B N 1 ATOM 6485 C CA . PHE B 1 298 ? -70.816 -28.024 65.973 1.00 65.22 ? 298 PHE B CA 1 ATOM 6486 C C . PHE B 1 298 ? -71.253 -27.753 64.537 1.00 65.24 ? 298 PHE B C 1 ATOM 6487 O O . PHE B 1 298 ? -71.147 -26.626 64.034 1.00 64.99 ? 298 PHE B O 1 ATOM 6488 C CB . PHE B 1 298 ? -69.508 -28.802 65.970 1.00 64.90 ? 298 PHE B CB 1 ATOM 6489 C CG . PHE B 1 298 ? -68.333 -28.010 65.456 1.00 64.26 ? 298 PHE B CG 1 ATOM 6490 C CD1 . PHE B 1 298 ? -67.999 -28.042 64.115 1.00 62.68 ? 298 PHE B CD1 1 ATOM 6491 C CD2 . PHE B 1 298 ? -67.560 -27.248 66.322 1.00 64.02 ? 298 PHE B CD2 1 ATOM 6492 C CE1 . PHE B 1 298 ? -66.924 -27.350 63.637 1.00 62.93 ? 298 PHE B CE1 1 ATOM 6493 C CE2 . PHE B 1 298 ? -66.467 -26.536 65.852 1.00 64.49 ? 298 PHE B CE2 1 ATOM 6494 C CZ . PHE B 1 298 ? -66.148 -26.583 64.499 1.00 64.33 ? 298 PHE B CZ 1 ATOM 6495 N N . LEU B 1 299 ? -71.705 -28.816 63.882 1.00 65.35 ? 299 LEU B N 1 ATOM 6496 C CA . LEU B 1 299 ? -72.352 -28.740 62.584 1.00 65.68 ? 299 LEU B CA 1 ATOM 6497 C C . LEU B 1 299 ? -73.832 -28.840 62.839 1.00 66.27 ? 299 LEU B C 1 ATOM 6498 O O . LEU B 1 299 ? -74.287 -29.815 63.451 1.00 66.49 ? 299 LEU B O 1 ATOM 6499 C CB . LEU B 1 299 ? -71.953 -29.931 61.728 1.00 65.26 ? 299 LEU B CB 1 ATOM 6500 C CG . LEU B 1 299 ? -70.820 -29.655 60.769 1.00 65.41 ? 299 LEU B CG 1 ATOM 6501 C CD1 . LEU B 1 299 ? -71.015 -30.531 59.554 1.00 66.89 ? 299 LEU B CD1 1 ATOM 6502 C CD2 . LEU B 1 299 ? -70.855 -28.196 60.375 1.00 66.16 ? 299 LEU B CD2 1 ATOM 6503 N N . THR B 1 300 ? -74.592 -27.854 62.373 1.00 66.86 ? 300 THR B N 1 ATOM 6504 C CA . THR B 1 300 ? -76.032 -27.819 62.672 1.00 67.47 ? 300 THR B CA 1 ATOM 6505 C C . THR B 1 300 ? -76.918 -28.321 61.541 1.00 67.67 ? 300 THR B C 1 ATOM 6506 O O . THR B 1 300 ? -78.128 -28.150 61.575 1.00 68.03 ? 300 THR B O 1 ATOM 6507 C CB . THR B 1 300 ? -76.504 -26.407 63.076 1.00 67.36 ? 300 THR B CB 1 ATOM 6508 O OG1 . THR B 1 300 ? -75.656 -25.434 62.456 1.00 67.70 ? 300 THR B OG1 1 ATOM 6509 C CG2 . THR B 1 300 ? -76.448 -26.235 64.597 1.00 67.49 ? 300 THR B CG2 1 ATOM 6510 N N . ASP B 1 301 ? -76.319 -28.954 60.547 1.00 68.01 ? 301 ASP B N 1 ATOM 6511 C CA . ASP B 1 301 ? -77.057 -29.377 59.372 1.00 68.55 ? 301 ASP B CA 1 ATOM 6512 C C . ASP B 1 301 ? -75.990 -29.816 58.410 1.00 68.38 ? 301 ASP B C 1 ATOM 6513 O O . ASP B 1 301 ? -74.834 -29.452 58.577 1.00 68.74 ? 301 ASP B O 1 ATOM 6514 C CB . ASP B 1 301 ? -77.859 -28.194 58.797 1.00 69.02 ? 301 ASP B CB 1 ATOM 6515 C CG . ASP B 1 301 ? -78.713 -28.576 57.559 1.00 70.77 ? 301 ASP B CG 1 ATOM 6516 O OD1 . ASP B 1 301 ? -79.481 -27.695 57.068 1.00 71.55 ? 301 ASP B OD1 1 ATOM 6517 O OD2 . ASP B 1 301 ? -78.615 -29.740 57.073 1.00 72.58 ? 301 ASP B OD2 1 ATOM 6518 N N . MET B 1 302 ? -76.349 -30.615 57.423 1.00 68.25 ? 302 MET B N 1 ATOM 6519 C CA . MET B 1 302 ? -75.351 -31.042 56.485 1.00 68.72 ? 302 MET B CA 1 ATOM 6520 C C . MET B 1 302 ? -74.684 -29.817 55.891 1.00 68.95 ? 302 MET B C 1 ATOM 6521 O O . MET B 1 302 ? -75.354 -28.848 55.517 1.00 68.97 ? 302 MET B O 1 ATOM 6522 C CB . MET B 1 302 ? -75.984 -31.882 55.417 1.00 68.95 ? 302 MET B CB 1 ATOM 6523 C CG . MET B 1 302 ? -76.853 -32.925 55.998 1.00 70.69 ? 302 MET B CG 1 ATOM 6524 S SD . MET B 1 302 ? -77.271 -34.097 54.722 1.00 75.89 ? 302 MET B SD 1 ATOM 6525 C CE . MET B 1 302 ? -75.708 -34.262 53.822 1.00 74.52 ? 302 MET B CE 1 ATOM 6526 N N . PRO B 1 303 ? -73.350 -29.846 55.810 1.00 69.06 ? 303 PRO B N 1 ATOM 6527 C CA . PRO B 1 303 ? -72.619 -28.635 55.494 1.00 69.04 ? 303 PRO B CA 1 ATOM 6528 C C . PRO B 1 303 ? -72.733 -28.238 54.022 1.00 68.87 ? 303 PRO B C 1 ATOM 6529 O O . PRO B 1 303 ? -72.686 -27.051 53.720 1.00 69.24 ? 303 PRO B O 1 ATOM 6530 C CB . PRO B 1 303 ? -71.174 -28.972 55.901 1.00 68.89 ? 303 PRO B CB 1 ATOM 6531 C CG . PRO B 1 303 ? -71.086 -30.424 55.729 1.00 69.32 ? 303 PRO B CG 1 ATOM 6532 C CD . PRO B 1 303 ? -72.459 -30.996 56.013 1.00 69.15 ? 303 PRO B CD 1 ATOM 6533 N N . ASP B 1 304 ? -72.896 -29.190 53.108 1.00 68.46 ? 304 ASP B N 1 ATOM 6534 C CA . ASP B 1 304 ? -73.066 -28.792 51.706 1.00 68.03 ? 304 ASP B CA 1 ATOM 6535 C C . ASP B 1 304 ? -74.281 -27.881 51.574 1.00 66.61 ? 304 ASP B C 1 ATOM 6536 O O . ASP B 1 304 ? -74.240 -26.862 50.904 1.00 66.49 ? 304 ASP B O 1 ATOM 6537 C CB . ASP B 1 304 ? -73.197 -30.001 50.776 1.00 68.73 ? 304 ASP B CB 1 ATOM 6538 C CG . ASP B 1 304 ? -74.208 -31.047 51.287 1.00 71.96 ? 304 ASP B CG 1 ATOM 6539 O OD1 . ASP B 1 304 ? -74.252 -31.302 52.536 1.00 73.96 ? 304 ASP B OD1 1 ATOM 6540 O OD2 . ASP B 1 304 ? -74.943 -31.620 50.421 1.00 74.41 ? 304 ASP B OD2 1 ATOM 6541 N N . ILE B 1 305 ? -75.363 -28.252 52.228 1.00 65.08 ? 305 ILE B N 1 ATOM 6542 C CA . ILE B 1 305 ? -76.503 -27.344 52.308 1.00 63.91 ? 305 ILE B CA 1 ATOM 6543 C C . ILE B 1 305 ? -76.154 -25.942 52.857 1.00 63.14 ? 305 ILE B C 1 ATOM 6544 O O . ILE B 1 305 ? -76.483 -24.943 52.242 1.00 62.79 ? 305 ILE B O 1 ATOM 6545 C CB . ILE B 1 305 ? -77.642 -27.958 53.113 1.00 63.84 ? 305 ILE B CB 1 ATOM 6546 C CG1 . ILE B 1 305 ? -78.048 -29.291 52.466 1.00 63.17 ? 305 ILE B CG1 1 ATOM 6547 C CG2 . ILE B 1 305 ? -78.807 -26.982 53.189 1.00 64.41 ? 305 ILE B CG2 1 ATOM 6548 C CD1 . ILE B 1 305 ? -79.069 -30.096 53.249 1.00 60.98 ? 305 ILE B CD1 1 ATOM 6549 N N . LEU B 1 306 ? -75.491 -25.866 54.010 1.00 62.42 ? 306 LEU B N 1 ATOM 6550 C CA . LEU B 1 306 ? -75.068 -24.576 54.574 1.00 61.54 ? 306 LEU B CA 1 ATOM 6551 C C . LEU B 1 306 ? -74.202 -23.753 53.612 1.00 61.27 ? 306 LEU B C 1 ATOM 6552 O O . LEU B 1 306 ? -74.295 -22.506 53.551 1.00 60.82 ? 306 LEU B O 1 ATOM 6553 C CB . LEU B 1 306 ? -74.284 -24.817 55.852 1.00 61.45 ? 306 LEU B CB 1 ATOM 6554 C CG . LEU B 1 306 ? -75.077 -25.579 56.910 1.00 61.87 ? 306 LEU B CG 1 ATOM 6555 C CD1 . LEU B 1 306 ? -74.164 -26.203 57.955 1.00 62.76 ? 306 LEU B CD1 1 ATOM 6556 C CD2 . LEU B 1 306 ? -76.070 -24.655 57.572 1.00 62.72 ? 306 LEU B CD2 1 ATOM 6557 N N . LEU B 1 307 ? -73.335 -24.458 52.883 1.00 60.66 ? 307 LEU B N 1 ATOM 6558 C CA . LEU B 1 307 ? -72.462 -23.816 51.916 1.00 60.10 ? 307 LEU B CA 1 ATOM 6559 C C . LEU B 1 307 ? -73.315 -23.396 50.742 1.00 60.12 ? 307 LEU B C 1 ATOM 6560 O O . LEU B 1 307 ? -73.134 -22.320 50.146 1.00 60.08 ? 307 LEU B O 1 ATOM 6561 C CB . LEU B 1 307 ? -71.362 -24.766 51.437 1.00 59.66 ? 307 LEU B CB 1 ATOM 6562 C CG . LEU B 1 307 ? -70.589 -24.267 50.207 1.00 58.56 ? 307 LEU B CG 1 ATOM 6563 C CD1 . LEU B 1 307 ? -69.837 -22.990 50.501 1.00 57.34 ? 307 LEU B CD1 1 ATOM 6564 C CD2 . LEU B 1 307 ? -69.649 -25.321 49.684 1.00 56.92 ? 307 LEU B CD2 1 ATOM 6565 N N . GLU B 1 308 ? -74.259 -24.256 50.398 1.00 60.00 ? 308 GLU B N 1 ATOM 6566 C CA . GLU B 1 308 ? -75.056 -23.981 49.230 1.00 60.38 ? 308 GLU B CA 1 ATOM 6567 C C . GLU B 1 308 ? -75.889 -22.723 49.431 1.00 60.02 ? 308 GLU B C 1 ATOM 6568 O O . GLU B 1 308 ? -76.072 -21.947 48.504 1.00 60.28 ? 308 GLU B O 1 ATOM 6569 C CB . GLU B 1 308 ? -75.946 -25.175 48.891 1.00 60.72 ? 308 GLU B CB 1 ATOM 6570 C CG . GLU B 1 308 ? -76.826 -24.936 47.700 1.00 63.00 ? 308 GLU B CG 1 ATOM 6571 C CD . GLU B 1 308 ? -76.005 -24.517 46.503 1.00 67.00 ? 308 GLU B CD 1 ATOM 6572 O OE1 . GLU B 1 308 ? -76.584 -23.952 45.542 1.00 68.49 ? 308 GLU B OE1 1 ATOM 6573 O OE2 . GLU B 1 308 ? -74.766 -24.735 46.550 1.00 68.11 ? 308 GLU B OE2 1 ATOM 6574 N N . LEU B 1 309 ? -76.375 -22.516 50.649 1.00 59.58 ? 309 LEU B N 1 ATOM 6575 C CA . LEU B 1 309 ? -77.343 -21.470 50.895 1.00 59.31 ? 309 LEU B CA 1 ATOM 6576 C C . LEU B 1 309 ? -76.744 -20.345 51.696 1.00 59.79 ? 309 LEU B C 1 ATOM 6577 O O . LEU B 1 309 ? -77.450 -19.652 52.424 1.00 59.75 ? 309 LEU B O 1 ATOM 6578 C CB . LEU B 1 309 ? -78.565 -22.031 51.613 1.00 58.95 ? 309 LEU B CB 1 ATOM 6579 C CG . LEU B 1 309 ? -79.165 -23.251 50.908 1.00 58.48 ? 309 LEU B CG 1 ATOM 6580 C CD1 . LEU B 1 309 ? -80.309 -23.894 51.695 1.00 58.67 ? 309 LEU B CD1 1 ATOM 6581 C CD2 . LEU B 1 309 ? -79.617 -22.881 49.525 1.00 58.05 ? 309 LEU B CD2 1 ATOM 6582 N N . GLY B 1 310 ? -75.436 -20.165 51.564 1.00 60.38 ? 310 GLY B N 1 ATOM 6583 C CA . GLY B 1 310 ? -74.764 -19.025 52.187 1.00 61.27 ? 310 GLY B CA 1 ATOM 6584 C C . GLY B 1 310 ? -74.950 -18.923 53.700 1.00 61.98 ? 310 GLY B C 1 ATOM 6585 O O . GLY B 1 310 ? -75.192 -17.832 54.250 1.00 62.06 ? 310 GLY B O 1 ATOM 6586 N N . GLN B 1 311 ? -74.807 -20.053 54.385 1.00 62.03 ? 311 GLN B N 1 ATOM 6587 C CA . GLN B 1 311 ? -74.888 -20.046 55.825 1.00 62.22 ? 311 GLN B CA 1 ATOM 6588 C C . GLN B 1 311 ? -73.542 -20.217 56.479 1.00 61.83 ? 311 GLN B C 1 ATOM 6589 O O . GLN B 1 311 ? -73.291 -21.226 57.137 1.00 61.79 ? 311 GLN B O 1 ATOM 6590 C CB . GLN B 1 311 ? -75.825 -21.142 56.260 1.00 62.65 ? 311 GLN B CB 1 ATOM 6591 C CG . GLN B 1 311 ? -77.212 -20.835 55.778 1.00 65.16 ? 311 GLN B CG 1 ATOM 6592 C CD . GLN B 1 311 ? -77.748 -19.554 56.407 1.00 68.01 ? 311 GLN B CD 1 ATOM 6593 O OE1 . GLN B 1 311 ? -77.955 -18.554 55.721 1.00 67.95 ? 311 GLN B OE1 1 ATOM 6594 N NE2 . GLN B 1 311 ? -77.959 -19.579 57.728 1.00 68.20 ? 311 GLN B NE2 1 ATOM 6595 N N . PHE B 1 312 ? -72.679 -19.223 56.318 1.00 61.36 ? 312 PHE B N 1 ATOM 6596 C CA . PHE B 1 312 ? -71.360 -19.306 56.935 1.00 61.16 ? 312 PHE B CA 1 ATOM 6597 C C . PHE B 1 312 ? -70.747 -17.948 57.226 1.00 60.86 ? 312 PHE B C 1 ATOM 6598 O O . PHE B 1 312 ? -71.240 -16.926 56.762 1.00 61.20 ? 312 PHE B O 1 ATOM 6599 C CB . PHE B 1 312 ? -70.444 -20.056 56.009 1.00 60.95 ? 312 PHE B CB 1 ATOM 6600 C CG . PHE B 1 312 ? -70.547 -19.604 54.599 1.00 60.70 ? 312 PHE B CG 1 ATOM 6601 C CD1 . PHE B 1 312 ? -69.770 -18.558 54.136 1.00 60.21 ? 312 PHE B CD1 1 ATOM 6602 C CD2 . PHE B 1 312 ? -71.430 -20.219 53.727 1.00 61.02 ? 312 PHE B CD2 1 ATOM 6603 C CE1 . PHE B 1 312 ? -69.862 -18.141 52.828 1.00 59.98 ? 312 PHE B CE1 1 ATOM 6604 C CE2 . PHE B 1 312 ? -71.517 -19.800 52.405 1.00 60.60 ? 312 PHE B CE2 1 ATOM 6605 C CZ . PHE B 1 312 ? -70.724 -18.765 51.961 1.00 59.91 ? 312 PHE B CZ 1 ATOM 6606 N N . LYS B 1 313 ? -69.663 -17.931 57.981 1.00 60.26 ? 313 LYS B N 1 ATOM 6607 C CA . LYS B 1 313 ? -69.009 -16.664 58.248 1.00 59.95 ? 313 LYS B CA 1 ATOM 6608 C C . LYS B 1 313 ? -68.711 -15.993 56.916 1.00 59.64 ? 313 LYS B C 1 ATOM 6609 O O . LYS B 1 313 ? -68.190 -16.646 55.997 1.00 59.49 ? 313 LYS B O 1 ATOM 6610 C CB . LYS B 1 313 ? -67.705 -16.871 59.035 1.00 60.05 ? 313 LYS B CB 1 ATOM 6611 C CG . LYS B 1 313 ? -66.888 -15.601 59.284 1.00 59.60 ? 313 LYS B CG 1 ATOM 6612 C CD . LYS B 1 313 ? -65.958 -15.749 60.488 1.00 60.42 ? 313 LYS B CD 1 ATOM 6613 C CE . LYS B 1 313 ? -65.873 -14.431 61.277 1.00 61.30 ? 313 LYS B CE 1 ATOM 6614 N NZ . LYS B 1 313 ? -64.478 -13.955 61.426 1.00 61.87 ? 313 LYS B NZ 1 ATOM 6615 N N . LYS B 1 314 ? -69.055 -14.705 56.815 1.00 59.09 ? 314 LYS B N 1 ATOM 6616 C CA . LYS B 1 314 ? -68.696 -13.892 55.667 1.00 58.97 ? 314 LYS B CA 1 ATOM 6617 C C . LYS B 1 314 ? -67.353 -13.224 55.910 1.00 58.87 ? 314 LYS B C 1 ATOM 6618 O O . LYS B 1 314 ? -67.201 -12.480 56.869 1.00 59.18 ? 314 LYS B O 1 ATOM 6619 C CB . LYS B 1 314 ? -69.776 -12.856 55.444 1.00 58.84 ? 314 LYS B CB 1 ATOM 6620 C CG . LYS B 1 314 ? -71.128 -13.496 55.236 1.00 60.13 ? 314 LYS B CG 1 ATOM 6621 C CD . LYS B 1 314 ? -71.080 -14.493 54.034 1.00 61.36 ? 314 LYS B CD 1 ATOM 6622 C CE . LYS B 1 314 ? -72.484 -14.952 53.574 1.00 61.66 ? 314 LYS B CE 1 ATOM 6623 N NZ . LYS B 1 314 ? -73.342 -15.581 54.648 1.00 61.11 ? 314 LYS B NZ 1 ATOM 6624 N N . THR B 1 315 ? -66.362 -13.510 55.076 1.00 58.62 ? 315 THR B N 1 ATOM 6625 C CA . THR B 1 315 ? -65.023 -12.976 55.304 1.00 58.83 ? 315 THR B CA 1 ATOM 6626 C C . THR B 1 315 ? -64.094 -13.412 54.184 1.00 58.52 ? 315 THR B C 1 ATOM 6627 O O . THR B 1 315 ? -64.464 -14.256 53.383 1.00 58.94 ? 315 THR B O 1 ATOM 6628 C CB . THR B 1 315 ? -64.454 -13.483 56.626 1.00 58.95 ? 315 THR B CB 1 ATOM 6629 O OG1 . THR B 1 315 ? -63.153 -12.932 56.830 1.00 60.33 ? 315 THR B OG1 1 ATOM 6630 C CG2 . THR B 1 315 ? -64.341 -14.989 56.584 1.00 59.76 ? 315 THR B CG2 1 ATOM 6631 N N . GLN B 1 316 ? -62.895 -12.854 54.097 1.00 58.19 ? 316 GLN B N 1 ATOM 6632 C CA . GLN B 1 316 ? -62.015 -13.286 53.015 1.00 58.25 ? 316 GLN B CA 1 ATOM 6633 C C . GLN B 1 316 ? -61.451 -14.683 53.290 1.00 58.35 ? 316 GLN B C 1 ATOM 6634 O O . GLN B 1 316 ? -61.374 -15.129 54.437 1.00 58.52 ? 316 GLN B O 1 ATOM 6635 C CB . GLN B 1 316 ? -60.881 -12.291 52.739 1.00 57.83 ? 316 GLN B CB 1 ATOM 6636 C CG . GLN B 1 316 ? -61.310 -10.871 52.845 1.00 57.98 ? 316 GLN B CG 1 ATOM 6637 C CD . GLN B 1 316 ? -61.700 -10.521 54.263 1.00 58.09 ? 316 GLN B CD 1 ATOM 6638 O OE1 . GLN B 1 316 ? -61.206 -11.122 55.202 1.00 59.77 ? 316 GLN B OE1 1 ATOM 6639 N NE2 . GLN B 1 316 ? -62.575 -9.551 54.428 1.00 57.11 ? 316 GLN B NE2 1 ATOM 6640 N N . ILE B 1 317 ? -61.060 -15.366 52.221 1.00 58.15 ? 317 ILE B N 1 ATOM 6641 C CA . ILE B 1 317 ? -60.472 -16.681 52.338 1.00 57.71 ? 317 ILE B CA 1 ATOM 6642 C C . ILE B 1 317 ? -59.400 -16.846 51.283 1.00 57.64 ? 317 ILE B C 1 ATOM 6643 O O . ILE B 1 317 ? -59.494 -16.306 50.170 1.00 57.69 ? 317 ILE B O 1 ATOM 6644 C CB . ILE B 1 317 ? -61.506 -17.780 52.127 1.00 57.79 ? 317 ILE B CB 1 ATOM 6645 C CG1 . ILE B 1 317 ? -62.220 -17.580 50.764 1.00 58.44 ? 317 ILE B CG1 1 ATOM 6646 C CG2 . ILE B 1 317 ? -62.457 -17.819 53.309 1.00 56.40 ? 317 ILE B CG2 1 ATOM 6647 C CD1 . ILE B 1 317 ? -63.017 -18.808 50.285 1.00 59.30 ? 317 ILE B CD1 1 ATOM 6648 N N . LEU B 1 318 ? -58.378 -17.601 51.652 1.00 57.16 ? 318 LEU B N 1 ATOM 6649 C CA . LEU B 1 318 ? -57.298 -17.903 50.758 1.00 56.81 ? 318 LEU B CA 1 ATOM 6650 C C . LEU B 1 318 ? -57.346 -19.421 50.627 1.00 56.62 ? 318 LEU B C 1 ATOM 6651 O O . LEU B 1 318 ? -57.396 -20.122 51.643 1.00 56.52 ? 318 LEU B O 1 ATOM 6652 C CB . LEU B 1 318 ? -55.993 -17.432 51.382 1.00 56.74 ? 318 LEU B CB 1 ATOM 6653 C CG . LEU B 1 318 ? -54.782 -17.330 50.464 1.00 57.15 ? 318 LEU B CG 1 ATOM 6654 C CD1 . LEU B 1 318 ? -53.836 -16.285 51.000 1.00 58.28 ? 318 LEU B CD1 1 ATOM 6655 C CD2 . LEU B 1 318 ? -54.091 -18.661 50.385 1.00 57.78 ? 318 LEU B CD2 1 ATOM 6656 N N . VAL B 1 319 ? -57.391 -19.928 49.393 1.00 55.97 ? 319 VAL B N 1 ATOM 6657 C CA . VAL B 1 319 ? -57.551 -21.354 49.188 1.00 55.61 ? 319 VAL B CA 1 ATOM 6658 C C . VAL B 1 319 ? -56.596 -21.755 48.104 1.00 55.93 ? 319 VAL B C 1 ATOM 6659 O O . VAL B 1 319 ? -56.283 -20.923 47.251 1.00 56.75 ? 319 VAL B O 1 ATOM 6660 C CB . VAL B 1 319 ? -58.952 -21.677 48.714 1.00 55.17 ? 319 VAL B CB 1 ATOM 6661 C CG1 . VAL B 1 319 ? -59.122 -23.150 48.666 1.00 55.57 ? 319 VAL B CG1 1 ATOM 6662 C CG2 . VAL B 1 319 ? -59.964 -21.107 49.632 1.00 55.86 ? 319 VAL B CG2 1 ATOM 6663 N N . GLY B 1 320 ? -56.126 -23.004 48.103 1.00 55.78 ? 320 GLY B N 1 ATOM 6664 C CA . GLY B 1 320 ? -55.189 -23.442 47.049 1.00 55.37 ? 320 GLY B CA 1 ATOM 6665 C C . GLY B 1 320 ? -54.821 -24.901 47.141 1.00 55.24 ? 320 GLY B C 1 ATOM 6666 O O . GLY B 1 320 ? -55.183 -25.570 48.107 1.00 55.54 ? 320 GLY B O 1 ATOM 6667 N N . VAL B 1 321 ? -54.099 -25.401 46.147 1.00 54.85 ? 321 VAL B N 1 ATOM 6668 C CA . VAL B 1 321 ? -53.758 -26.818 46.103 1.00 54.93 ? 321 VAL B CA 1 ATOM 6669 C C . VAL B 1 321 ? -52.400 -26.990 45.436 1.00 55.48 ? 321 VAL B C 1 ATOM 6670 O O . VAL B 1 321 ? -51.851 -26.036 44.890 1.00 55.85 ? 321 VAL B O 1 ATOM 6671 C CB . VAL B 1 321 ? -54.789 -27.626 45.309 1.00 54.67 ? 321 VAL B CB 1 ATOM 6672 C CG1 . VAL B 1 321 ? -56.146 -27.564 45.960 1.00 54.20 ? 321 VAL B CG1 1 ATOM 6673 C CG2 . VAL B 1 321 ? -54.880 -27.109 43.886 1.00 54.93 ? 321 VAL B CG2 1 ATOM 6674 N N . ASN B 1 322 ? -51.856 -28.199 45.475 1.00 55.98 ? 322 ASN B N 1 ATOM 6675 C CA . ASN B 1 322 ? -50.572 -28.470 44.843 1.00 56.65 ? 322 ASN B CA 1 ATOM 6676 C C . ASN B 1 322 ? -50.746 -29.237 43.550 1.00 57.20 ? 322 ASN B C 1 ATOM 6677 O O . ASN B 1 322 ? -51.690 -30.026 43.400 1.00 57.56 ? 322 ASN B O 1 ATOM 6678 C CB . ASN B 1 322 ? -49.695 -29.321 45.752 1.00 56.89 ? 322 ASN B CB 1 ATOM 6679 C CG . ASN B 1 322 ? -49.471 -28.692 47.089 1.00 57.45 ? 322 ASN B CG 1 ATOM 6680 O OD1 . ASN B 1 322 ? -48.976 -29.336 48.014 1.00 58.66 ? 322 ASN B OD1 1 ATOM 6681 N ND2 . ASN B 1 322 ? -49.842 -27.431 47.213 1.00 57.87 ? 322 ASN B ND2 1 ATOM 6682 N N . LYS B 1 323 ? -49.798 -29.043 42.639 1.00 57.52 ? 323 LYS B N 1 ATOM 6683 C CA . LYS B 1 323 ? -49.853 -29.641 41.308 1.00 57.88 ? 323 LYS B CA 1 ATOM 6684 C C . LYS B 1 323 ? -50.177 -31.121 41.292 1.00 58.09 ? 323 LYS B C 1 ATOM 6685 O O . LYS B 1 323 ? -50.854 -31.572 40.373 1.00 58.36 ? 323 LYS B O 1 ATOM 6686 C CB . LYS B 1 323 ? -48.552 -29.375 40.526 1.00 58.04 ? 323 LYS B CB 1 ATOM 6687 C CG . LYS B 1 323 ? -48.539 -29.920 39.092 1.00 59.24 ? 323 LYS B CG 1 ATOM 6688 C CD . LYS B 1 323 ? -48.189 -28.834 38.025 1.00 61.80 ? 323 LYS B CD 1 ATOM 6689 C CE . LYS B 1 323 ? -46.916 -29.145 37.254 1.00 63.28 ? 323 LYS B CE 1 ATOM 6690 N NZ . LYS B 1 323 ? -46.483 -30.543 37.566 1.00 64.57 ? 323 LYS B NZ 1 ATOM 6691 N N . ASP B 1 324 ? -49.715 -31.878 42.289 1.00 58.50 ? 324 ASP B N 1 ATOM 6692 C CA . ASP B 1 324 ? -49.843 -33.343 42.255 1.00 59.00 ? 324 ASP B CA 1 ATOM 6693 C C . ASP B 1 324 ? -50.396 -33.959 43.521 1.00 59.43 ? 324 ASP B C 1 ATOM 6694 O O . ASP B 1 324 ? -49.799 -34.882 44.066 1.00 59.69 ? 324 ASP B O 1 ATOM 6695 C CB . ASP B 1 324 ? -48.483 -33.972 41.985 1.00 58.82 ? 324 ASP B CB 1 ATOM 6696 C CG . ASP B 1 324 ? -47.945 -33.594 40.650 1.00 59.39 ? 324 ASP B CG 1 ATOM 6697 O OD1 . ASP B 1 324 ? -48.655 -33.878 39.659 1.00 61.00 ? 324 ASP B OD1 1 ATOM 6698 O OD2 . ASP B 1 324 ? -46.843 -32.999 40.589 1.00 59.17 ? 324 ASP B OD2 1 ATOM 6699 N N . GLU B 1 325 ? -51.529 -33.466 43.991 1.00 59.91 ? 325 GLU B N 1 ATOM 6700 C CA . GLU B 1 325 ? -52.070 -33.933 45.264 1.00 60.56 ? 325 GLU B CA 1 ATOM 6701 C C . GLU B 1 325 ? -52.153 -35.449 45.362 1.00 60.95 ? 325 GLU B C 1 ATOM 6702 O O . GLU B 1 325 ? -52.006 -36.022 46.443 1.00 61.15 ? 325 GLU B O 1 ATOM 6703 C CB . GLU B 1 325 ? -53.459 -33.351 45.473 1.00 60.70 ? 325 GLU B CB 1 ATOM 6704 C CG . GLU B 1 325 ? -53.469 -31.840 45.563 1.00 61.45 ? 325 GLU B CG 1 ATOM 6705 C CD . GLU B 1 325 ? -53.097 -31.352 46.956 1.00 62.67 ? 325 GLU B CD 1 ATOM 6706 O OE1 . GLU B 1 325 ? -53.069 -32.178 47.897 1.00 62.71 ? 325 GLU B OE1 1 ATOM 6707 O OE2 . GLU B 1 325 ? -52.835 -30.137 47.109 1.00 64.23 ? 325 GLU B OE2 1 ATOM 6708 N N . GLY B 1 326 ? -52.394 -36.101 44.228 1.00 61.39 ? 326 GLY B N 1 ATOM 6709 C CA . GLY B 1 326 ? -52.709 -37.535 44.223 1.00 61.55 ? 326 GLY B CA 1 ATOM 6710 C C . GLY B 1 326 ? -51.573 -38.502 44.528 1.00 61.55 ? 326 GLY B C 1 ATOM 6711 O O . GLY B 1 326 ? -51.752 -39.465 45.287 1.00 61.70 ? 326 GLY B O 1 ATOM 6712 N N . THR B 1 327 ? -50.407 -38.252 43.936 1.00 61.44 ? 327 THR B N 1 ATOM 6713 C CA . THR B 1 327 ? -49.329 -39.235 43.921 1.00 61.47 ? 327 THR B CA 1 ATOM 6714 C C . THR B 1 327 ? -49.021 -39.844 45.292 1.00 61.97 ? 327 THR B C 1 ATOM 6715 O O . THR B 1 327 ? -48.887 -41.065 45.428 1.00 61.62 ? 327 THR B O 1 ATOM 6716 C CB . THR B 1 327 ? -48.059 -38.634 43.343 1.00 61.26 ? 327 THR B CB 1 ATOM 6717 O OG1 . THR B 1 327 ? -47.635 -37.557 44.179 1.00 60.49 ? 327 THR B OG1 1 ATOM 6718 C CG2 . THR B 1 327 ? -48.339 -38.113 41.948 1.00 61.00 ? 327 THR B CG2 1 ATOM 6719 N N . ALA B 1 328 ? -48.914 -38.989 46.306 1.00 62.72 ? 328 ALA B N 1 ATOM 6720 C CA . ALA B 1 328 ? -48.476 -39.426 47.640 1.00 63.19 ? 328 ALA B CA 1 ATOM 6721 C C . ALA B 1 328 ? -49.165 -40.682 48.127 1.00 63.43 ? 328 ALA B C 1 ATOM 6722 O O . ALA B 1 328 ? -48.588 -41.433 48.900 1.00 63.65 ? 328 ALA B O 1 ATOM 6723 C CB . ALA B 1 328 ? -48.660 -38.316 48.665 1.00 63.34 ? 328 ALA B CB 1 ATOM 6724 N N . PHE B 1 329 ? -50.400 -40.905 47.696 1.00 63.61 ? 329 PHE B N 1 ATOM 6725 C CA . PHE B 1 329 ? -51.166 -42.023 48.210 1.00 63.84 ? 329 PHE B CA 1 ATOM 6726 C C . PHE B 1 329 ? -51.030 -43.259 47.310 1.00 64.43 ? 329 PHE B C 1 ATOM 6727 O O . PHE B 1 329 ? -51.362 -44.376 47.710 1.00 64.29 ? 329 PHE B O 1 ATOM 6728 C CB . PHE B 1 329 ? -52.637 -41.651 48.312 1.00 63.57 ? 329 PHE B CB 1 ATOM 6729 C CG . PHE B 1 329 ? -52.908 -40.405 49.096 1.00 63.05 ? 329 PHE B CG 1 ATOM 6730 C CD1 . PHE B 1 329 ? -52.745 -39.141 48.519 1.00 63.30 ? 329 PHE B CD1 1 ATOM 6731 C CD2 . PHE B 1 329 ? -53.388 -40.490 50.393 1.00 61.63 ? 329 PHE B CD2 1 ATOM 6732 C CE1 . PHE B 1 329 ? -53.026 -37.982 49.249 1.00 61.89 ? 329 PHE B CE1 1 ATOM 6733 C CE2 . PHE B 1 329 ? -53.669 -39.353 51.118 1.00 60.26 ? 329 PHE B CE2 1 ATOM 6734 C CZ . PHE B 1 329 ? -53.491 -38.094 50.547 1.00 60.66 ? 329 PHE B CZ 1 ATOM 6735 N N . LEU B 1 330 ? -50.576 -43.073 46.081 1.00 65.02 ? 330 LEU B N 1 ATOM 6736 C CA . LEU B 1 330 ? -50.479 -44.223 45.205 1.00 65.90 ? 330 LEU B CA 1 ATOM 6737 C C . LEU B 1 330 ? -49.665 -45.332 45.861 1.00 66.75 ? 330 LEU B C 1 ATOM 6738 O O . LEU B 1 330 ? -49.950 -46.528 45.688 1.00 66.98 ? 330 LEU B O 1 ATOM 6739 C CB . LEU B 1 330 ? -49.889 -43.827 43.860 1.00 65.60 ? 330 LEU B CB 1 ATOM 6740 C CG . LEU B 1 330 ? -50.870 -42.839 43.233 1.00 64.77 ? 330 LEU B CG 1 ATOM 6741 C CD1 . LEU B 1 330 ? -50.398 -42.392 41.849 1.00 63.70 ? 330 LEU B CD1 1 ATOM 6742 C CD2 . LEU B 1 330 ? -52.260 -43.450 43.204 1.00 62.82 ? 330 LEU B CD2 1 ATOM 6743 N N . VAL B 1 331 ? -48.665 -44.938 46.642 1.00 67.41 ? 331 VAL B N 1 ATOM 6744 C CA . VAL B 1 331 ? -47.691 -45.912 47.145 1.00 67.98 ? 331 VAL B CA 1 ATOM 6745 C C . VAL B 1 331 ? -48.166 -46.712 48.372 1.00 68.62 ? 331 VAL B C 1 ATOM 6746 O O . VAL B 1 331 ? -47.405 -47.500 48.941 1.00 69.28 ? 331 VAL B O 1 ATOM 6747 C CB . VAL B 1 331 ? -46.333 -45.247 47.435 1.00 67.64 ? 331 VAL B CB 1 ATOM 6748 C CG1 . VAL B 1 331 ? -45.647 -44.885 46.150 1.00 67.76 ? 331 VAL B CG1 1 ATOM 6749 C CG2 . VAL B 1 331 ? -46.524 -44.012 48.294 1.00 67.85 ? 331 VAL B CG2 1 ATOM 6750 N N . TYR B 1 332 ? -49.413 -46.513 48.788 1.00 68.92 ? 332 TYR B N 1 ATOM 6751 C CA . TYR B 1 332 ? -49.960 -47.242 49.933 1.00 69.11 ? 332 TYR B CA 1 ATOM 6752 C C . TYR B 1 332 ? -51.001 -48.255 49.495 1.00 69.83 ? 332 TYR B C 1 ATOM 6753 O O . TYR B 1 332 ? -51.966 -48.504 50.231 1.00 69.77 ? 332 TYR B O 1 ATOM 6754 C CB . TYR B 1 332 ? -50.601 -46.279 50.934 1.00 68.81 ? 332 TYR B CB 1 ATOM 6755 C CG . TYR B 1 332 ? -49.596 -45.432 51.656 1.00 68.63 ? 332 TYR B CG 1 ATOM 6756 C CD1 . TYR B 1 332 ? -48.762 -44.549 50.964 1.00 68.93 ? 332 TYR B CD1 1 ATOM 6757 C CD2 . TYR B 1 332 ? -49.470 -45.516 53.032 1.00 68.75 ? 332 TYR B CD2 1 ATOM 6758 C CE1 . TYR B 1 332 ? -47.828 -43.775 51.636 1.00 69.11 ? 332 TYR B CE1 1 ATOM 6759 C CE2 . TYR B 1 332 ? -48.545 -44.753 53.719 1.00 68.72 ? 332 TYR B CE2 1 ATOM 6760 C CZ . TYR B 1 332 ? -47.727 -43.884 53.026 1.00 69.29 ? 332 TYR B CZ 1 ATOM 6761 O OH . TYR B 1 332 ? -46.806 -43.138 53.746 1.00 70.41 ? 332 TYR B OH 1 ATOM 6762 N N . GLY B 1 333 ? -50.833 -48.821 48.299 1.00 70.55 ? 333 GLY B N 1 ATOM 6763 C CA . GLY B 1 333 ? -51.775 -49.830 47.839 1.00 71.47 ? 333 GLY B CA 1 ATOM 6764 C C . GLY B 1 333 ? -52.030 -49.946 46.351 1.00 72.02 ? 333 GLY B C 1 ATOM 6765 O O . GLY B 1 333 ? -52.591 -50.936 45.892 1.00 72.01 ? 333 GLY B O 1 ATOM 6766 N N . ALA B 1 334 ? -51.644 -48.946 45.578 1.00 72.95 ? 334 ALA B N 1 ATOM 6767 C CA . ALA B 1 334 ? -51.854 -49.056 44.133 1.00 73.70 ? 334 ALA B CA 1 ATOM 6768 C C . ALA B 1 334 ? -50.814 -49.974 43.501 1.00 74.06 ? 334 ALA B C 1 ATOM 6769 O O . ALA B 1 334 ? -49.613 -49.670 43.484 1.00 73.95 ? 334 ALA B O 1 ATOM 6770 C CB . ALA B 1 334 ? -51.883 -47.691 43.447 1.00 73.55 ? 334 ALA B CB 1 ATOM 6771 N N . PRO B 1 335 ? -51.292 -51.111 42.984 1.00 74.49 ? 335 PRO B N 1 ATOM 6772 C CA . PRO B 1 335 ? -50.518 -52.161 42.325 1.00 74.88 ? 335 PRO B CA 1 ATOM 6773 C C . PRO B 1 335 ? -49.634 -51.608 41.209 1.00 75.28 ? 335 PRO B C 1 ATOM 6774 O O . PRO B 1 335 ? -50.138 -51.102 40.201 1.00 75.41 ? 335 PRO B O 1 ATOM 6775 C CB . PRO B 1 335 ? -51.601 -53.064 41.732 1.00 75.01 ? 335 PRO B CB 1 ATOM 6776 C CG . PRO B 1 335 ? -52.816 -52.822 42.591 1.00 74.46 ? 335 PRO B CG 1 ATOM 6777 C CD . PRO B 1 335 ? -52.743 -51.377 42.945 1.00 74.47 ? 335 PRO B CD 1 ATOM 6778 N N . GLY B 1 336 ? -48.324 -51.694 41.399 1.00 75.73 ? 336 GLY B N 1 ATOM 6779 C CA . GLY B 1 336 ? -47.384 -51.213 40.396 1.00 76.20 ? 336 GLY B CA 1 ATOM 6780 C C . GLY B 1 336 ? -46.589 -50.048 40.936 1.00 76.76 ? 336 GLY B C 1 ATOM 6781 O O . GLY B 1 336 ? -45.547 -49.685 40.381 1.00 76.73 ? 336 GLY B O 1 ATOM 6782 N N . PHE B 1 337 ? -47.079 -49.461 42.027 1.00 77.41 ? 337 PHE B N 1 ATOM 6783 C CA . PHE B 1 337 ? -46.486 -48.231 42.554 1.00 78.22 ? 337 PHE B CA 1 ATOM 6784 C C . PHE B 1 337 ? -45.523 -48.504 43.686 1.00 78.54 ? 337 PHE B C 1 ATOM 6785 O O . PHE B 1 337 ? -45.915 -49.026 44.725 1.00 78.52 ? 337 PHE B O 1 ATOM 6786 C CB . PHE B 1 337 ? -47.567 -47.241 43.020 1.00 78.32 ? 337 PHE B CB 1 ATOM 6787 C CG . PHE B 1 337 ? -48.329 -46.608 41.898 1.00 78.59 ? 337 PHE B CG 1 ATOM 6788 C CD1 . PHE B 1 337 ? -49.580 -47.081 41.542 1.00 79.16 ? 337 PHE B CD1 1 ATOM 6789 C CD2 . PHE B 1 337 ? -47.788 -45.551 41.183 1.00 79.12 ? 337 PHE B CD2 1 ATOM 6790 C CE1 . PHE B 1 337 ? -50.291 -46.507 40.488 1.00 79.28 ? 337 PHE B CE1 1 ATOM 6791 C CE2 . PHE B 1 337 ? -48.496 -44.962 40.140 1.00 78.88 ? 337 PHE B CE2 1 ATOM 6792 C CZ . PHE B 1 337 ? -49.750 -45.443 39.791 1.00 79.03 ? 337 PHE B CZ 1 ATOM 6793 N N . SER B 1 338 ? -44.261 -48.152 43.476 1.00 79.16 ? 338 SER B N 1 ATOM 6794 C CA . SER B 1 338 ? -43.278 -48.182 44.551 1.00 79.96 ? 338 SER B CA 1 ATOM 6795 C C . SER B 1 338 ? -42.623 -46.813 44.656 1.00 80.26 ? 338 SER B C 1 ATOM 6796 O O . SER B 1 338 ? -42.528 -46.093 43.648 1.00 80.35 ? 338 SER B O 1 ATOM 6797 C CB . SER B 1 338 ? -42.210 -49.247 44.294 1.00 79.98 ? 338 SER B CB 1 ATOM 6798 O OG . SER B 1 338 ? -41.108 -49.070 45.176 1.00 80.11 ? 338 SER B OG 1 ATOM 6799 N N . LYS B 1 339 ? -42.174 -46.436 45.854 1.00 80.42 ? 339 LYS B N 1 ATOM 6800 C CA . LYS B 1 339 ? -41.403 -45.205 45.929 1.00 80.87 ? 339 LYS B CA 1 ATOM 6801 C C . LYS B 1 339 ? -40.019 -45.408 45.293 1.00 81.31 ? 339 LYS B C 1 ATOM 6802 O O . LYS B 1 339 ? -39.290 -44.436 45.069 1.00 81.46 ? 339 LYS B O 1 ATOM 6803 C CB . LYS B 1 339 ? -41.304 -44.667 47.359 1.00 80.80 ? 339 LYS B CB 1 ATOM 6804 C CG . LYS B 1 339 ? -40.453 -45.489 48.316 1.00 80.66 ? 339 LYS B CG 1 ATOM 6805 C CD . LYS B 1 339 ? -40.058 -44.633 49.525 1.00 80.34 ? 339 LYS B CD 1 ATOM 6806 C CE . LYS B 1 339 ? -39.006 -45.323 50.378 1.00 79.70 ? 339 LYS B CE 1 ATOM 6807 N NZ . LYS B 1 339 ? -37.892 -45.806 49.531 1.00 79.32 ? 339 LYS B NZ 1 ATOM 6808 N N . ASP B 1 340 ? -39.692 -46.665 44.966 1.00 81.67 ? 340 ASP B N 1 ATOM 6809 C CA . ASP B 1 340 ? -38.360 -47.030 44.448 1.00 82.12 ? 340 ASP B CA 1 ATOM 6810 C C . ASP B 1 340 ? -38.223 -47.217 42.918 1.00 82.84 ? 340 ASP B C 1 ATOM 6811 O O . ASP B 1 340 ? -37.311 -46.642 42.316 1.00 83.19 ? 340 ASP B O 1 ATOM 6812 C CB . ASP B 1 340 ? -37.787 -48.210 45.228 1.00 81.69 ? 340 ASP B CB 1 ATOM 6813 C CG . ASP B 1 340 ? -37.703 -47.917 46.697 1.00 81.17 ? 340 ASP B CG 1 ATOM 6814 O OD1 . ASP B 1 340 ? -38.152 -48.756 47.497 1.00 80.53 ? 340 ASP B OD1 1 ATOM 6815 O OD2 . ASP B 1 340 ? -37.216 -46.822 47.057 1.00 80.55 ? 340 ASP B OD2 1 ATOM 6816 N N . ASN B 1 341 ? -39.096 -48.003 42.275 1.00 83.40 ? 341 ASN B N 1 ATOM 6817 C CA . ASN B 1 341 ? -39.146 -47.970 40.798 1.00 83.71 ? 341 ASN B CA 1 ATOM 6818 C C . ASN B 1 341 ? -39.993 -46.783 40.302 1.00 83.53 ? 341 ASN B C 1 ATOM 6819 O O . ASN B 1 341 ? -40.842 -46.266 41.039 1.00 83.59 ? 341 ASN B O 1 ATOM 6820 C CB . ASN B 1 341 ? -39.508 -49.336 40.134 1.00 83.87 ? 341 ASN B CB 1 ATOM 6821 C CG . ASN B 1 341 ? -40.818 -49.962 40.648 1.00 85.32 ? 341 ASN B CG 1 ATOM 6822 O OD1 . ASN B 1 341 ? -41.619 -49.309 41.320 1.00 86.10 ? 341 ASN B OD1 1 ATOM 6823 N ND2 . ASN B 1 341 ? -41.033 -51.248 40.305 1.00 87.12 ? 341 ASN B ND2 1 ATOM 6824 N N . ASN B 1 342 ? -39.744 -46.317 39.085 1.00 83.30 ? 342 ASN B N 1 ATOM 6825 C CA . ASN B 1 342 ? -40.519 -45.183 38.586 1.00 83.26 ? 342 ASN B CA 1 ATOM 6826 C C . ASN B 1 342 ? -41.962 -45.552 38.170 1.00 82.77 ? 342 ASN B C 1 ATOM 6827 O O . ASN B 1 342 ? -42.619 -44.875 37.364 1.00 82.41 ? 342 ASN B O 1 ATOM 6828 C CB . ASN B 1 342 ? -39.750 -44.418 37.506 1.00 83.55 ? 342 ASN B CB 1 ATOM 6829 C CG . ASN B 1 342 ? -39.829 -45.074 36.148 1.00 84.76 ? 342 ASN B CG 1 ATOM 6830 O OD1 . ASN B 1 342 ? -40.357 -46.182 35.992 1.00 85.90 ? 342 ASN B OD1 1 ATOM 6831 N ND2 . ASN B 1 342 ? -39.304 -44.382 35.140 1.00 86.44 ? 342 ASN B ND2 1 ATOM 6832 N N . SER B 1 343 ? -42.427 -46.658 38.742 1.00 82.37 ? 343 SER B N 1 ATOM 6833 C CA . SER B 1 343 ? -43.850 -47.005 38.800 1.00 82.10 ? 343 SER B CA 1 ATOM 6834 C C . SER B 1 343 ? -44.668 -46.847 37.514 1.00 81.85 ? 343 SER B C 1 ATOM 6835 O O . SER B 1 343 ? -45.810 -46.406 37.569 1.00 81.68 ? 343 SER B O 1 ATOM 6836 C CB . SER B 1 343 ? -44.535 -46.222 39.936 1.00 82.01 ? 343 SER B CB 1 ATOM 6837 O OG . SER B 1 343 ? -44.184 -46.735 41.206 1.00 81.68 ? 343 SER B OG 1 ATOM 6838 N N . ILE B 1 344 ? -44.101 -47.203 36.369 1.00 81.62 ? 344 ILE B N 1 ATOM 6839 C CA . ILE B 1 344 ? -44.907 -47.328 35.158 1.00 81.55 ? 344 ILE B CA 1 ATOM 6840 C C . ILE B 1 344 ? -45.878 -48.498 35.348 1.00 81.95 ? 344 ILE B C 1 ATOM 6841 O O . ILE B 1 344 ? -45.480 -49.557 35.825 1.00 82.10 ? 344 ILE B O 1 ATOM 6842 C CB . ILE B 1 344 ? -44.050 -47.608 33.932 1.00 81.19 ? 344 ILE B CB 1 ATOM 6843 C CG1 . ILE B 1 344 ? -42.996 -46.519 33.769 1.00 80.76 ? 344 ILE B CG1 1 ATOM 6844 C CG2 . ILE B 1 344 ? -44.921 -47.700 32.707 1.00 81.28 ? 344 ILE B CG2 1 ATOM 6845 C CD1 . ILE B 1 344 ? -43.568 -45.180 33.439 1.00 80.37 ? 344 ILE B CD1 1 ATOM 6846 N N . ILE B 1 345 ? -47.152 -48.309 35.006 1.00 82.35 ? 345 ILE B N 1 ATOM 6847 C CA . ILE B 1 345 ? -48.155 -49.349 35.239 1.00 82.56 ? 345 ILE B CA 1 ATOM 6848 C C . ILE B 1 345 ? -48.961 -49.576 33.975 1.00 82.98 ? 345 ILE B C 1 ATOM 6849 O O . ILE B 1 345 ? -48.906 -48.757 33.054 1.00 83.02 ? 345 ILE B O 1 ATOM 6850 C CB . ILE B 1 345 ? -49.133 -48.991 36.387 1.00 82.51 ? 345 ILE B CB 1 ATOM 6851 C CG1 . ILE B 1 345 ? -49.859 -47.684 36.073 1.00 82.79 ? 345 ILE B CG1 1 ATOM 6852 C CG2 . ILE B 1 345 ? -48.420 -48.935 37.748 1.00 81.87 ? 345 ILE B CG2 1 ATOM 6853 C CD1 . ILE B 1 345 ? -51.000 -47.405 37.020 1.00 83.08 ? 345 ILE B CD1 1 ATOM 6854 N N . THR B 1 346 ? -49.707 -50.685 33.945 1.00 83.33 ? 346 THR B N 1 ATOM 6855 C CA . THR B 1 346 ? -50.459 -51.104 32.759 1.00 83.45 ? 346 THR B CA 1 ATOM 6856 C C . THR B 1 346 ? -51.934 -50.769 32.854 1.00 83.82 ? 346 THR B C 1 ATOM 6857 O O . THR B 1 346 ? -52.481 -50.633 33.943 1.00 83.83 ? 346 THR B O 1 ATOM 6858 C CB . THR B 1 346 ? -50.374 -52.627 32.535 1.00 83.36 ? 346 THR B CB 1 ATOM 6859 O OG1 . THR B 1 346 ? -50.761 -53.313 33.732 1.00 82.38 ? 346 THR B OG1 1 ATOM 6860 C CG2 . THR B 1 346 ? -48.973 -53.046 32.121 1.00 83.19 ? 346 THR B CG2 1 ATOM 6861 N N . ARG B 1 347 ? -52.583 -50.659 31.703 1.00 84.33 ? 347 ARG B N 1 ATOM 6862 C CA . ARG B 1 347 ? -54.011 -50.422 31.681 1.00 85.00 ? 347 ARG B CA 1 ATOM 6863 C C . ARG B 1 347 ? -54.709 -51.322 32.704 1.00 85.23 ? 347 ARG B C 1 ATOM 6864 O O . ARG B 1 347 ? -55.645 -50.901 33.391 1.00 84.87 ? 347 ARG B O 1 ATOM 6865 C CB . ARG B 1 347 ? -54.578 -50.669 30.278 1.00 85.20 ? 347 ARG B CB 1 ATOM 6866 C CG . ARG B 1 347 ? -56.101 -50.529 30.217 1.00 86.03 ? 347 ARG B CG 1 ATOM 6867 C CD . ARG B 1 347 ? -56.715 -50.887 28.849 1.00 87.28 ? 347 ARG B CD 1 ATOM 6868 N NE . ARG B 1 347 ? -58.164 -50.649 28.846 1.00 87.98 ? 347 ARG B NE 1 ATOM 6869 C CZ . ARG B 1 347 ? -58.733 -49.457 28.628 1.00 88.10 ? 347 ARG B CZ 1 ATOM 6870 N NH1 . ARG B 1 347 ? -60.060 -49.318 28.661 1.00 87.61 ? 347 ARG B NH1 1 ATOM 6871 N NH2 . ARG B 1 347 ? -57.977 -48.393 28.381 1.00 87.81 ? 347 ARG B NH2 1 ATOM 6872 N N . LYS B 1 348 ? -54.237 -52.564 32.798 1.00 85.82 ? 348 LYS B N 1 ATOM 6873 C CA . LYS B 1 348 ? -54.866 -53.580 33.659 1.00 86.15 ? 348 LYS B CA 1 ATOM 6874 C C . LYS B 1 348 ? -54.697 -53.147 35.103 1.00 85.87 ? 348 LYS B C 1 ATOM 6875 O O . LYS B 1 348 ? -55.585 -53.311 35.938 1.00 85.86 ? 348 LYS B O 1 ATOM 6876 C CB . LYS B 1 348 ? -54.206 -54.946 33.445 1.00 86.46 ? 348 LYS B CB 1 ATOM 6877 C CG . LYS B 1 348 ? -55.037 -56.141 33.871 1.00 87.65 ? 348 LYS B CG 1 ATOM 6878 C CD . LYS B 1 348 ? -55.872 -56.633 32.710 1.00 90.23 ? 348 LYS B CD 1 ATOM 6879 C CE . LYS B 1 348 ? -56.073 -58.151 32.761 1.00 91.11 ? 348 LYS B CE 1 ATOM 6880 N NZ . LYS B 1 348 ? -57.087 -58.557 33.762 1.00 91.74 ? 348 LYS B NZ 1 ATOM 6881 N N . GLU B 1 349 ? -53.536 -52.574 35.380 1.00 85.70 ? 349 GLU B N 1 ATOM 6882 C CA . GLU B 1 349 ? -53.195 -52.143 36.721 1.00 85.50 ? 349 GLU B CA 1 ATOM 6883 C C . GLU B 1 349 ? -53.922 -50.867 37.087 1.00 85.12 ? 349 GLU B C 1 ATOM 6884 O O . GLU B 1 349 ? -54.320 -50.676 38.230 1.00 85.25 ? 349 GLU B O 1 ATOM 6885 C CB . GLU B 1 349 ? -51.690 -51.934 36.833 1.00 85.56 ? 349 GLU B CB 1 ATOM 6886 C CG . GLU B 1 349 ? -50.926 -53.224 36.833 1.00 85.93 ? 349 GLU B CG 1 ATOM 6887 C CD . GLU B 1 349 ? -49.437 -53.013 36.820 1.00 86.25 ? 349 GLU B CD 1 ATOM 6888 O OE1 . GLU B 1 349 ? -48.772 -53.550 37.730 1.00 86.42 ? 349 GLU B OE1 1 ATOM 6889 O OE2 . GLU B 1 349 ? -48.935 -52.316 35.906 1.00 85.94 ? 349 GLU B OE2 1 ATOM 6890 N N . PHE B 1 350 ? -54.094 -49.988 36.115 1.00 84.59 ? 350 PHE B N 1 ATOM 6891 C CA . PHE B 1 350 ? -54.858 -48.794 36.363 1.00 84.17 ? 350 PHE B CA 1 ATOM 6892 C C . PHE B 1 350 ? -56.254 -49.204 36.841 1.00 84.06 ? 350 PHE B C 1 ATOM 6893 O O . PHE B 1 350 ? -56.710 -48.787 37.913 1.00 83.74 ? 350 PHE B O 1 ATOM 6894 C CB . PHE B 1 350 ? -54.932 -47.945 35.101 1.00 84.07 ? 350 PHE B CB 1 ATOM 6895 C CG . PHE B 1 350 ? -55.777 -46.724 35.253 1.00 83.61 ? 350 PHE B CG 1 ATOM 6896 C CD1 . PHE B 1 350 ? -55.212 -45.514 35.594 1.00 83.91 ? 350 PHE B CD1 1 ATOM 6897 C CD2 . PHE B 1 350 ? -57.143 -46.787 35.062 1.00 83.88 ? 350 PHE B CD2 1 ATOM 6898 C CE1 . PHE B 1 350 ? -55.993 -44.383 35.724 1.00 84.26 ? 350 PHE B CE1 1 ATOM 6899 C CE2 . PHE B 1 350 ? -57.929 -45.662 35.198 1.00 84.20 ? 350 PHE B CE2 1 ATOM 6900 C CZ . PHE B 1 350 ? -57.353 -44.459 35.531 1.00 84.12 ? 350 PHE B CZ 1 ATOM 6901 N N . GLN B 1 351 ? -56.922 -50.041 36.052 1.00 84.05 ? 351 GLN B N 1 ATOM 6902 C CA . GLN B 1 351 ? -58.234 -50.531 36.443 1.00 84.13 ? 351 GLN B CA 1 ATOM 6903 C C . GLN B 1 351 ? -58.099 -51.035 37.862 1.00 84.13 ? 351 GLN B C 1 ATOM 6904 O O . GLN B 1 351 ? -58.934 -50.767 38.724 1.00 84.03 ? 351 GLN B O 1 ATOM 6905 C CB . GLN B 1 351 ? -58.715 -51.653 35.517 1.00 84.26 ? 351 GLN B CB 1 ATOM 6906 C CG . GLN B 1 351 ? -59.335 -51.189 34.188 1.00 84.91 ? 351 GLN B CG 1 ATOM 6907 C CD . GLN B 1 351 ? -58.917 -52.067 33.011 1.00 86.52 ? 351 GLN B CD 1 ATOM 6908 O OE1 . GLN B 1 351 ? -58.331 -53.136 33.197 1.00 88.08 ? 351 GLN B OE1 1 ATOM 6909 N NE2 . GLN B 1 351 ? -59.204 -51.615 31.796 1.00 86.82 ? 351 GLN B NE2 1 ATOM 6910 N N . GLU B 1 352 ? -57.020 -51.757 38.111 1.00 84.17 ? 352 GLU B N 1 ATOM 6911 C CA . GLU B 1 352 ? -56.800 -52.298 39.438 1.00 84.33 ? 352 GLU B CA 1 ATOM 6912 C C . GLU B 1 352 ? -56.713 -51.203 40.500 1.00 83.72 ? 352 GLU B C 1 ATOM 6913 O O . GLU B 1 352 ? -57.305 -51.327 41.574 1.00 83.69 ? 352 GLU B O 1 ATOM 6914 C CB . GLU B 1 352 ? -55.551 -53.187 39.455 1.00 84.80 ? 352 GLU B CB 1 ATOM 6915 C CG . GLU B 1 352 ? -55.769 -54.574 38.835 1.00 86.64 ? 352 GLU B CG 1 ATOM 6916 C CD . GLU B 1 352 ? -57.041 -55.276 39.352 1.00 89.17 ? 352 GLU B CD 1 ATOM 6917 O OE1 . GLU B 1 352 ? -57.407 -55.133 40.558 1.00 89.35 ? 352 GLU B OE1 1 ATOM 6918 O OE2 . GLU B 1 352 ? -57.674 -55.983 38.534 1.00 89.96 ? 352 GLU B OE2 1 ATOM 6919 N N . GLY B 1 353 ? -55.982 -50.133 40.183 1.00 82.99 ? 353 GLY B N 1 ATOM 6920 C CA . GLY B 1 353 ? -55.822 -49.006 41.094 1.00 81.96 ? 353 GLY B CA 1 ATOM 6921 C C . GLY B 1 353 ? -57.163 -48.378 41.432 1.00 81.36 ? 353 GLY B C 1 ATOM 6922 O O . GLY B 1 353 ? -57.415 -47.969 42.575 1.00 81.19 ? 353 GLY B O 1 ATOM 6923 N N . LEU B 1 354 ? -58.039 -48.315 40.433 1.00 80.59 ? 354 LEU B N 1 ATOM 6924 C CA . LEU B 1 354 ? -59.341 -47.696 40.625 1.00 79.68 ? 354 LEU B CA 1 ATOM 6925 C C . LEU B 1 354 ? -60.133 -48.449 41.669 1.00 79.31 ? 354 LEU B C 1 ATOM 6926 O O . LEU B 1 354 ? -60.885 -47.849 42.431 1.00 78.97 ? 354 LEU B O 1 ATOM 6927 C CB . LEU B 1 354 ? -60.117 -47.611 39.311 1.00 79.42 ? 354 LEU B CB 1 ATOM 6928 C CG . LEU B 1 354 ? -59.679 -46.461 38.409 1.00 79.20 ? 354 LEU B CG 1 ATOM 6929 C CD1 . LEU B 1 354 ? -60.479 -46.400 37.138 1.00 78.75 ? 354 LEU B CD1 1 ATOM 6930 C CD2 . LEU B 1 354 ? -59.840 -45.184 39.156 1.00 79.59 ? 354 LEU B CD2 1 ATOM 6931 N N . LYS B 1 355 ? -59.949 -49.765 41.714 1.00 79.14 ? 355 LYS B N 1 ATOM 6932 C CA . LYS B 1 355 ? -60.740 -50.594 42.599 1.00 79.16 ? 355 LYS B CA 1 ATOM 6933 C C . LYS B 1 355 ? -60.349 -50.276 44.002 1.00 78.93 ? 355 LYS B C 1 ATOM 6934 O O . LYS B 1 355 ? -61.179 -50.352 44.911 1.00 79.03 ? 355 LYS B O 1 ATOM 6935 C CB . LYS B 1 355 ? -60.485 -52.078 42.367 1.00 79.47 ? 355 LYS B CB 1 ATOM 6936 C CG . LYS B 1 355 ? -60.445 -52.500 40.930 1.00 80.84 ? 355 LYS B CG 1 ATOM 6937 C CD . LYS B 1 355 ? -60.717 -53.986 40.821 1.00 83.89 ? 355 LYS B CD 1 ATOM 6938 C CE . LYS B 1 355 ? -60.602 -54.439 39.373 1.00 85.69 ? 355 LYS B CE 1 ATOM 6939 N NZ . LYS B 1 355 ? -60.953 -55.876 39.185 1.00 86.35 ? 355 LYS B NZ 1 ATOM 6940 N N . ILE B 1 356 ? -59.075 -49.928 44.175 1.00 78.57 ? 356 ILE B N 1 ATOM 6941 C CA . ILE B 1 356 ? -58.535 -49.641 45.497 1.00 78.20 ? 356 ILE B CA 1 ATOM 6942 C C . ILE B 1 356 ? -59.093 -48.343 46.071 1.00 77.89 ? 356 ILE B C 1 ATOM 6943 O O . ILE B 1 356 ? -59.505 -48.297 47.234 1.00 78.05 ? 356 ILE B O 1 ATOM 6944 C CB . ILE B 1 356 ? -57.008 -49.557 45.488 1.00 78.29 ? 356 ILE B CB 1 ATOM 6945 C CG1 . ILE B 1 356 ? -56.388 -50.932 45.229 1.00 78.09 ? 356 ILE B CG1 1 ATOM 6946 C CG2 . ILE B 1 356 ? -56.523 -49.037 46.834 1.00 78.75 ? 356 ILE B CG2 1 ATOM 6947 C CD1 . ILE B 1 356 ? -56.658 -51.921 46.355 1.00 77.34 ? 356 ILE B CD1 1 ATOM 6948 N N . PHE B 1 357 ? -59.119 -47.298 45.248 1.00 77.29 ? 357 PHE B N 1 ATOM 6949 C CA . PHE B 1 357 ? -59.547 -45.968 45.692 1.00 76.74 ? 357 PHE B CA 1 ATOM 6950 C C . PHE B 1 357 ? -61.057 -45.715 45.643 1.00 76.84 ? 357 PHE B C 1 ATOM 6951 O O . PHE B 1 357 ? -61.562 -44.812 46.304 1.00 76.52 ? 357 PHE B O 1 ATOM 6952 C CB . PHE B 1 357 ? -58.815 -44.888 44.898 1.00 76.57 ? 357 PHE B CB 1 ATOM 6953 C CG . PHE B 1 357 ? -57.375 -44.736 45.277 1.00 75.21 ? 357 PHE B CG 1 ATOM 6954 C CD1 . PHE B 1 357 ? -57.014 -43.943 46.353 1.00 73.98 ? 357 PHE B CD1 1 ATOM 6955 C CD2 . PHE B 1 357 ? -56.385 -45.394 44.568 1.00 74.22 ? 357 PHE B CD2 1 ATOM 6956 C CE1 . PHE B 1 357 ? -55.704 -43.800 46.712 1.00 73.22 ? 357 PHE B CE1 1 ATOM 6957 C CE2 . PHE B 1 357 ? -55.065 -45.258 44.923 1.00 73.40 ? 357 PHE B CE2 1 ATOM 6958 C CZ . PHE B 1 357 ? -54.725 -44.458 46.000 1.00 73.43 ? 357 PHE B CZ 1 ATOM 6959 N N . PHE B 1 358 ? -61.773 -46.496 44.848 1.00 77.09 ? 358 PHE B N 1 ATOM 6960 C CA . PHE B 1 358 ? -63.214 -46.401 44.823 1.00 77.46 ? 358 PHE B CA 1 ATOM 6961 C C . PHE B 1 358 ? -63.737 -47.791 45.011 1.00 78.28 ? 358 PHE B C 1 ATOM 6962 O O . PHE B 1 358 ? -64.131 -48.437 44.054 1.00 78.68 ? 358 PHE B O 1 ATOM 6963 C CB . PHE B 1 358 ? -63.678 -45.841 43.491 1.00 77.03 ? 358 PHE B CB 1 ATOM 6964 C CG . PHE B 1 358 ? -62.969 -44.597 43.104 1.00 75.89 ? 358 PHE B CG 1 ATOM 6965 C CD1 . PHE B 1 358 ? -61.767 -44.661 42.438 1.00 74.70 ? 358 PHE B CD1 1 ATOM 6966 C CD2 . PHE B 1 358 ? -63.482 -43.353 43.441 1.00 75.34 ? 358 PHE B CD2 1 ATOM 6967 C CE1 . PHE B 1 358 ? -61.095 -43.502 42.091 1.00 74.27 ? 358 PHE B CE1 1 ATOM 6968 C CE2 . PHE B 1 358 ? -62.810 -42.184 43.098 1.00 73.86 ? 358 PHE B CE2 1 ATOM 6969 C CZ . PHE B 1 358 ? -61.620 -42.262 42.421 1.00 73.73 ? 358 PHE B CZ 1 ATOM 6970 N N . PRO B 1 359 ? -63.731 -48.274 46.259 1.00 79.14 ? 359 PRO B N 1 ATOM 6971 C CA . PRO B 1 359 ? -64.159 -49.652 46.494 1.00 79.35 ? 359 PRO B CA 1 ATOM 6972 C C . PRO B 1 359 ? -65.660 -49.790 46.231 1.00 79.42 ? 359 PRO B C 1 ATOM 6973 O O . PRO B 1 359 ? -66.059 -50.581 45.370 1.00 79.87 ? 359 PRO B O 1 ATOM 6974 C CB . PRO B 1 359 ? -63.837 -49.883 47.979 1.00 79.46 ? 359 PRO B CB 1 ATOM 6975 C CG . PRO B 1 359 ? -63.913 -48.504 48.612 1.00 79.80 ? 359 PRO B CG 1 ATOM 6976 C CD . PRO B 1 359 ? -63.604 -47.490 47.507 1.00 79.49 ? 359 PRO B CD 1 ATOM 6977 N N . GLY B 1 360 ? -66.475 -48.998 46.931 1.00 79.03 ? 360 GLY B N 1 ATOM 6978 C CA . GLY B 1 360 ? -67.925 -49.116 46.822 1.00 78.56 ? 360 GLY B CA 1 ATOM 6979 C C . GLY B 1 360 ? -68.554 -48.737 45.483 1.00 78.06 ? 360 GLY B C 1 ATOM 6980 O O . GLY B 1 360 ? -69.709 -49.061 45.215 1.00 78.24 ? 360 GLY B O 1 ATOM 6981 N N . VAL B 1 361 ? -67.798 -48.062 44.630 1.00 77.42 ? 361 VAL B N 1 ATOM 6982 C CA . VAL B 1 361 ? -68.366 -47.478 43.416 1.00 76.57 ? 361 VAL B CA 1 ATOM 6983 C C . VAL B 1 361 ? -68.766 -48.490 42.332 1.00 76.08 ? 361 VAL B C 1 ATOM 6984 O O . VAL B 1 361 ? -67.962 -49.344 41.953 1.00 75.92 ? 361 VAL B O 1 ATOM 6985 C CB . VAL B 1 361 ? -67.412 -46.411 42.848 1.00 76.53 ? 361 VAL B CB 1 ATOM 6986 C CG1 . VAL B 1 361 ? -67.761 -46.062 41.413 1.00 76.10 ? 361 VAL B CG1 1 ATOM 6987 C CG2 . VAL B 1 361 ? -67.450 -45.188 43.730 1.00 76.04 ? 361 VAL B CG2 1 ATOM 6988 N N . SER B 1 362 ? -70.012 -48.370 41.854 1.00 75.38 ? 362 SER B N 1 ATOM 6989 C CA . SER B 1 362 ? -70.571 -49.181 40.750 1.00 74.74 ? 362 SER B CA 1 ATOM 6990 C C . SER B 1 362 ? -69.577 -49.484 39.644 1.00 74.36 ? 362 SER B C 1 ATOM 6991 O O . SER B 1 362 ? -68.644 -48.729 39.421 1.00 74.36 ? 362 SER B O 1 ATOM 6992 C CB . SER B 1 362 ? -71.776 -48.471 40.123 1.00 74.90 ? 362 SER B CB 1 ATOM 6993 O OG . SER B 1 362 ? -71.407 -47.707 38.980 1.00 74.09 ? 362 SER B OG 1 ATOM 6994 N N . GLU B 1 363 ? -69.797 -50.577 38.927 1.00 74.08 ? 363 GLU B N 1 ATOM 6995 C CA . GLU B 1 363 ? -68.876 -50.963 37.858 1.00 73.72 ? 363 GLU B CA 1 ATOM 6996 C C . GLU B 1 363 ? -68.905 -49.906 36.776 1.00 73.37 ? 363 GLU B C 1 ATOM 6997 O O . GLU B 1 363 ? -67.900 -49.598 36.157 1.00 73.50 ? 363 GLU B O 1 ATOM 6998 C CB . GLU B 1 363 ? -69.237 -52.331 37.263 1.00 73.75 ? 363 GLU B CB 1 ATOM 6999 C CG . GLU B 1 363 ? -68.044 -53.038 36.624 1.00 73.87 ? 363 GLU B CG 1 ATOM 7000 C CD . GLU B 1 363 ? -66.933 -53.319 37.627 0.50 73.83 ? 363 GLU B CD 1 ATOM 7001 O OE1 . GLU B 1 363 ? -65.810 -52.820 37.426 0.50 73.65 ? 363 GLU B OE1 1 ATOM 7002 O OE2 . GLU B 1 363 ? -67.185 -54.027 38.625 0.50 73.83 ? 363 GLU B OE2 1 ATOM 7003 N N . PHE B 1 364 ? -70.079 -49.341 36.564 1.00 72.99 ? 364 PHE B N 1 ATOM 7004 C CA . PHE B 1 364 ? -70.233 -48.242 35.636 1.00 72.40 ? 364 PHE B CA 1 ATOM 7005 C C . PHE B 1 364 ? -69.407 -47.029 36.094 1.00 71.89 ? 364 PHE B C 1 ATOM 7006 O O . PHE B 1 364 ? -68.631 -46.461 35.329 1.00 70.94 ? 364 PHE B O 1 ATOM 7007 C CB . PHE B 1 364 ? -71.720 -47.883 35.551 1.00 72.45 ? 364 PHE B CB 1 ATOM 7008 C CG . PHE B 1 364 ? -72.007 -46.630 34.755 1.00 72.12 ? 364 PHE B CG 1 ATOM 7009 C CD1 . PHE B 1 364 ? -72.714 -45.569 35.329 1.00 71.01 ? 364 PHE B CD1 1 ATOM 7010 C CD2 . PHE B 1 364 ? -71.572 -46.509 33.442 1.00 70.98 ? 364 PHE B CD2 1 ATOM 7011 C CE1 . PHE B 1 364 ? -72.979 -44.427 34.606 1.00 69.87 ? 364 PHE B CE1 1 ATOM 7012 C CE2 . PHE B 1 364 ? -71.837 -45.363 32.722 1.00 69.77 ? 364 PHE B CE2 1 ATOM 7013 C CZ . PHE B 1 364 ? -72.535 -44.327 33.297 1.00 69.46 ? 364 PHE B CZ 1 ATOM 7014 N N . GLY B 1 365 ? -69.593 -46.641 37.355 1.00 71.73 ? 365 GLY B N 1 ATOM 7015 C CA . GLY B 1 365 ? -68.880 -45.504 37.930 1.00 71.64 ? 365 GLY B CA 1 ATOM 7016 C C . GLY B 1 365 ? -67.383 -45.562 37.681 1.00 71.72 ? 365 GLY B C 1 ATOM 7017 O O . GLY B 1 365 ? -66.759 -44.557 37.329 1.00 71.84 ? 365 GLY B O 1 ATOM 7018 N N . LYS B 1 366 ? -66.789 -46.735 37.867 1.00 71.66 ? 366 LYS B N 1 ATOM 7019 C CA . LYS B 1 366 ? -65.359 -46.886 37.636 1.00 71.44 ? 366 LYS B CA 1 ATOM 7020 C C . LYS B 1 366 ? -65.056 -46.789 36.143 1.00 71.29 ? 366 LYS B C 1 ATOM 7021 O O . LYS B 1 366 ? -64.019 -46.292 35.737 1.00 70.85 ? 366 LYS B O 1 ATOM 7022 C CB . LYS B 1 366 ? -64.849 -48.182 38.276 1.00 71.39 ? 366 LYS B CB 1 ATOM 7023 C CG . LYS B 1 366 ? -65.195 -48.286 39.764 1.00 71.38 ? 366 LYS B CG 1 ATOM 7024 C CD . LYS B 1 366 ? -64.297 -49.278 40.467 1.00 71.87 ? 366 LYS B CD 1 ATOM 7025 C CE . LYS B 1 366 ? -64.740 -50.709 40.251 1.00 72.25 ? 366 LYS B CE 1 ATOM 7026 N NZ . LYS B 1 366 ? -65.922 -50.962 41.099 1.00 72.68 ? 366 LYS B NZ 1 ATOM 7027 N N . GLU B 1 367 ? -65.986 -47.247 35.327 1.00 71.69 ? 367 GLU B N 1 ATOM 7028 C CA . GLU B 1 367 ? -65.790 -47.178 33.901 1.00 72.46 ? 367 GLU B CA 1 ATOM 7029 C C . GLU B 1 367 ? -65.671 -45.708 33.457 1.00 72.38 ? 367 GLU B C 1 ATOM 7030 O O . GLU B 1 367 ? -64.806 -45.375 32.626 1.00 72.33 ? 367 GLU B O 1 ATOM 7031 C CB . GLU B 1 367 ? -66.940 -47.890 33.174 1.00 72.70 ? 367 GLU B CB 1 ATOM 7032 C CG . GLU B 1 367 ? -66.802 -49.377 33.045 0.50 74.11 ? 367 GLU B CG 1 ATOM 7033 C CD . GLU B 1 367 ? -66.512 -49.756 31.626 0.50 76.65 ? 367 GLU B CD 1 ATOM 7034 O OE1 . GLU B 1 367 ? -67.262 -50.596 31.056 1.00 78.05 ? 367 GLU B OE1 1 ATOM 7035 O OE2 . GLU B 1 367 ? -65.550 -49.171 31.078 1.00 77.63 ? 367 GLU B OE2 1 ATOM 7036 N N . SER B 1 368 ? -66.529 -44.840 34.009 1.00 72.13 ? 368 SER B N 1 ATOM 7037 C CA . SER B 1 368 ? -66.564 -43.436 33.598 1.00 71.82 ? 368 SER B CA 1 ATOM 7038 C C . SER B 1 368 ? -65.249 -42.819 33.895 1.00 71.84 ? 368 SER B C 1 ATOM 7039 O O . SER B 1 368 ? -64.669 -42.117 33.065 1.00 71.75 ? 368 SER B O 1 ATOM 7040 C CB . SER B 1 368 ? -67.579 -42.668 34.387 1.00 71.51 ? 368 SER B CB 1 ATOM 7041 O OG . SER B 1 368 ? -68.085 -43.474 35.414 1.00 72.65 ? 368 SER B OG 1 ATOM 7042 N N . ILE B 1 369 ? -64.795 -43.045 35.119 1.00 71.95 ? 369 ILE B N 1 ATOM 7043 C CA . ILE B 1 369 ? -63.461 -42.600 35.496 1.00 71.93 ? 369 ILE B CA 1 ATOM 7044 C C . ILE B 1 369 ? -62.416 -43.085 34.480 1.00 72.38 ? 369 ILE B C 1 ATOM 7045 O O . ILE B 1 369 ? -61.648 -42.299 33.941 1.00 72.20 ? 369 ILE B O 1 ATOM 7046 C CB . ILE B 1 369 ? -63.100 -43.042 36.916 1.00 71.54 ? 369 ILE B CB 1 ATOM 7047 C CG1 . ILE B 1 369 ? -64.228 -42.673 37.876 1.00 70.69 ? 369 ILE B CG1 1 ATOM 7048 C CG2 . ILE B 1 369 ? -61.808 -42.385 37.351 1.00 71.50 ? 369 ILE B CG2 1 ATOM 7049 C CD1 . ILE B 1 369 ? -63.997 -43.111 39.310 1.00 69.16 ? 369 ILE B CD1 1 ATOM 7050 N N . LEU B 1 370 ? -62.404 -44.378 34.197 1.00 73.27 ? 370 LEU B N 1 ATOM 7051 C CA . LEU B 1 370 ? -61.440 -44.886 33.236 1.00 74.31 ? 370 LEU B CA 1 ATOM 7052 C C . LEU B 1 370 ? -61.563 -44.091 31.981 1.00 75.41 ? 370 LEU B C 1 ATOM 7053 O O . LEU B 1 370 ? -60.581 -43.649 31.410 1.00 75.40 ? 370 LEU B O 1 ATOM 7054 C CB . LEU B 1 370 ? -61.702 -46.342 32.887 1.00 74.08 ? 370 LEU B CB 1 ATOM 7055 C CG . LEU B 1 370 ? -60.561 -46.961 32.079 1.00 73.39 ? 370 LEU B CG 1 ATOM 7056 C CD1 . LEU B 1 370 ? -60.475 -48.426 32.387 1.00 73.71 ? 370 LEU B CD1 1 ATOM 7057 C CD2 . LEU B 1 370 ? -60.726 -46.773 30.589 1.00 74.51 ? 370 LEU B CD2 1 ATOM 7058 N N . PHE B 1 371 ? -62.801 -43.927 31.549 1.00 77.12 ? 371 PHE B N 1 ATOM 7059 C CA . PHE B 1 371 ? -63.091 -43.332 30.267 1.00 78.83 ? 371 PHE B CA 1 ATOM 7060 C C . PHE B 1 371 ? -62.641 -41.883 30.189 1.00 79.54 ? 371 PHE B C 1 ATOM 7061 O O . PHE B 1 371 ? -62.010 -41.467 29.203 1.00 79.83 ? 371 PHE B O 1 ATOM 7062 C CB . PHE B 1 371 ? -64.589 -43.432 29.968 1.00 79.25 ? 371 PHE B CB 1 ATOM 7063 C CG . PHE B 1 371 ? -64.998 -42.723 28.703 1.00 81.60 ? 371 PHE B CG 1 ATOM 7064 C CD1 . PHE B 1 371 ? -65.684 -41.510 28.762 1.00 83.14 ? 371 PHE B CD1 1 ATOM 7065 C CD2 . PHE B 1 371 ? -64.667 -43.252 27.450 1.00 83.81 ? 371 PHE B CD2 1 ATOM 7066 C CE1 . PHE B 1 371 ? -66.049 -40.834 27.596 1.00 84.21 ? 371 PHE B CE1 1 ATOM 7067 C CE2 . PHE B 1 371 ? -65.027 -42.585 26.274 1.00 84.86 ? 371 PHE B CE2 1 ATOM 7068 C CZ . PHE B 1 371 ? -65.724 -41.371 26.351 1.00 84.88 ? 371 PHE B CZ 1 ATOM 7069 N N . HIS B 1 372 ? -62.958 -41.109 31.220 1.00 80.41 ? 372 HIS B N 1 ATOM 7070 C CA . HIS B 1 372 ? -62.662 -39.697 31.161 1.00 81.37 ? 372 HIS B CA 1 ATOM 7071 C C . HIS B 1 372 ? -61.169 -39.434 31.241 1.00 81.65 ? 372 HIS B C 1 ATOM 7072 O O . HIS B 1 372 ? -60.656 -38.581 30.531 1.00 81.82 ? 372 HIS B O 1 ATOM 7073 C CB . HIS B 1 372 ? -63.391 -38.925 32.243 1.00 81.86 ? 372 HIS B CB 1 ATOM 7074 C CG . HIS B 1 372 ? -63.147 -37.450 32.177 1.00 84.49 ? 372 HIS B CG 1 ATOM 7075 N ND1 . HIS B 1 372 ? -64.116 -36.552 31.779 1.00 86.26 ? 372 HIS B ND1 1 ATOM 7076 C CD2 . HIS B 1 372 ? -62.032 -36.717 32.430 1.00 86.53 ? 372 HIS B CD2 1 ATOM 7077 C CE1 . HIS B 1 372 ? -63.612 -35.326 31.809 1.00 87.07 ? 372 HIS B CE1 1 ATOM 7078 N NE2 . HIS B 1 372 ? -62.348 -35.398 32.193 1.00 87.16 ? 372 HIS B NE2 1 ATOM 7079 N N . TYR B 1 373 ? -60.461 -40.170 32.090 1.00 82.35 ? 373 TYR B N 1 ATOM 7080 C CA . TYR B 1 373 ? -59.046 -39.883 32.308 1.00 83.10 ? 373 TYR B CA 1 ATOM 7081 C C . TYR B 1 373 ? -58.083 -40.583 31.357 1.00 84.45 ? 373 TYR B C 1 ATOM 7082 O O . TYR B 1 373 ? -56.944 -40.153 31.216 1.00 84.80 ? 373 TYR B O 1 ATOM 7083 C CB . TYR B 1 373 ? -58.634 -40.156 33.757 1.00 82.62 ? 373 TYR B CB 1 ATOM 7084 C CG . TYR B 1 373 ? -58.953 -39.028 34.719 1.00 81.29 ? 373 TYR B CG 1 ATOM 7085 C CD1 . TYR B 1 373 ? -58.100 -37.941 34.866 1.00 80.40 ? 373 TYR B CD1 1 ATOM 7086 C CD2 . TYR B 1 373 ? -60.106 -39.051 35.478 1.00 79.71 ? 373 TYR B CD2 1 ATOM 7087 C CE1 . TYR B 1 373 ? -58.405 -36.905 35.740 1.00 79.73 ? 373 TYR B CE1 1 ATOM 7088 C CE2 . TYR B 1 373 ? -60.413 -38.034 36.344 1.00 78.83 ? 373 TYR B CE2 1 ATOM 7089 C CZ . TYR B 1 373 ? -59.569 -36.962 36.480 1.00 78.96 ? 373 TYR B CZ 1 ATOM 7090 O OH . TYR B 1 373 ? -59.897 -35.948 37.363 1.00 78.06 ? 373 TYR B OH 1 ATOM 7091 N N . THR B 1 374 ? -58.507 -41.652 30.701 1.00 86.04 ? 374 THR B N 1 ATOM 7092 C CA . THR B 1 374 ? -57.582 -42.336 29.813 1.00 87.73 ? 374 THR B CA 1 ATOM 7093 C C . THR B 1 374 ? -57.903 -42.076 28.363 1.00 88.88 ? 374 THR B C 1 ATOM 7094 O O . THR B 1 374 ? -57.934 -42.980 27.548 1.00 88.97 ? 374 THR B O 1 ATOM 7095 C CB . THR B 1 374 ? -57.519 -43.849 30.066 1.00 87.80 ? 374 THR B CB 1 ATOM 7096 O OG1 . THR B 1 374 ? -58.757 -44.452 29.675 1.00 88.16 ? 374 THR B OG1 1 ATOM 7097 C CG2 . THR B 1 374 ? -57.237 -44.133 31.529 1.00 87.83 ? 374 THR B CG2 1 ATOM 7098 N N . ASP B 1 375 ? -58.135 -40.823 28.038 1.00 90.71 ? 375 ASP B N 1 ATOM 7099 C CA . ASP B 1 375 ? -58.314 -40.448 26.656 1.00 92.55 ? 375 ASP B CA 1 ATOM 7100 C C . ASP B 1 375 ? -57.033 -39.776 26.123 1.00 93.20 ? 375 ASP B C 1 ATOM 7101 O O . ASP B 1 375 ? -56.967 -38.553 26.007 1.00 93.22 ? 375 ASP B O 1 ATOM 7102 C CB . ASP B 1 375 ? -59.501 -39.508 26.567 1.00 92.98 ? 375 ASP B CB 1 ATOM 7103 C CG . ASP B 1 375 ? -59.901 -39.221 25.151 1.00 94.34 ? 375 ASP B CG 1 ATOM 7104 O OD1 . ASP B 1 375 ? -59.855 -40.152 24.305 1.00 95.27 ? 375 ASP B OD1 1 ATOM 7105 O OD2 . ASP B 1 375 ? -60.270 -38.054 24.898 1.00 96.11 ? 375 ASP B OD2 1 ATOM 7106 N N . TRP B 1 376 ? -56.029 -40.597 25.798 1.00 94.19 ? 376 TRP B N 1 ATOM 7107 C CA . TRP B 1 376 ? -54.632 -40.145 25.628 1.00 94.89 ? 376 TRP B CA 1 ATOM 7108 C C . TRP B 1 376 ? -54.401 -39.124 24.534 1.00 95.34 ? 376 TRP B C 1 ATOM 7109 O O . TRP B 1 376 ? -55.070 -39.139 23.495 1.00 95.58 ? 376 TRP B O 1 ATOM 7110 C CB . TRP B 1 376 ? -53.690 -41.327 25.383 1.00 94.89 ? 376 TRP B CB 1 ATOM 7111 C CG . TRP B 1 376 ? -53.730 -42.312 26.460 1.00 95.34 ? 376 TRP B CG 1 ATOM 7112 C CD1 . TRP B 1 376 ? -53.716 -43.667 26.336 1.00 96.17 ? 376 TRP B CD1 1 ATOM 7113 C CD2 . TRP B 1 376 ? -53.829 -42.033 27.854 1.00 95.61 ? 376 TRP B CD2 1 ATOM 7114 N NE1 . TRP B 1 376 ? -53.781 -44.257 27.579 1.00 96.51 ? 376 TRP B NE1 1 ATOM 7115 C CE2 . TRP B 1 376 ? -53.854 -43.272 28.527 1.00 95.77 ? 376 TRP B CE2 1 ATOM 7116 C CE3 . TRP B 1 376 ? -53.893 -40.857 28.600 1.00 95.62 ? 376 TRP B CE3 1 ATOM 7117 C CZ2 . TRP B 1 376 ? -53.937 -43.365 29.909 1.00 95.37 ? 376 TRP B CZ2 1 ATOM 7118 C CZ3 . TRP B 1 376 ? -53.978 -40.951 29.968 1.00 95.74 ? 376 TRP B CZ3 1 ATOM 7119 C CH2 . TRP B 1 376 ? -53.995 -42.195 30.611 1.00 95.58 ? 376 TRP B CH2 1 ATOM 7120 N N . VAL B 1 377 ? -53.416 -38.260 24.769 1.00 95.69 ? 377 VAL B N 1 ATOM 7121 C CA . VAL B 1 377 ? -53.034 -37.226 23.813 1.00 95.76 ? 377 VAL B CA 1 ATOM 7122 C C . VAL B 1 377 ? -51.955 -37.742 22.836 1.00 95.73 ? 377 VAL B C 1 ATOM 7123 O O . VAL B 1 377 ? -51.788 -38.956 22.623 1.00 95.28 ? 377 VAL B O 1 ATOM 7124 C CB . VAL B 1 377 ? -52.533 -35.951 24.549 1.00 95.85 ? 377 VAL B CB 1 ATOM 7125 C CG1 . VAL B 1 377 ? -53.175 -34.705 23.948 1.00 95.84 ? 377 VAL B CG1 1 ATOM 7126 C CG2 . VAL B 1 377 ? -52.818 -36.044 26.065 1.00 95.84 ? 377 VAL B CG2 1 ATOM 7127 N N . GLN B 1 380 ? -49.261 -44.447 23.433 1.00 103.10 ? 380 GLN B N 1 ATOM 7128 C CA . GLN B 1 380 ? -47.926 -44.170 22.914 1.00 103.39 ? 380 GLN B CA 1 ATOM 7129 C C . GLN B 1 380 ? -46.902 -43.826 24.028 1.00 103.29 ? 380 GLN B C 1 ATOM 7130 O O . GLN B 1 380 ? -45.765 -44.305 23.986 1.00 103.47 ? 380 GLN B O 1 ATOM 7131 C CB . GLN B 1 380 ? -47.973 -43.098 21.803 1.00 103.41 ? 380 GLN B CB 1 ATOM 7132 C CG . GLN B 1 380 ? -47.847 -41.631 22.263 1.00 104.18 ? 380 GLN B CG 1 ATOM 7133 C CD . GLN B 1 380 ? -49.179 -40.970 22.690 1.00 105.19 ? 380 GLN B CD 1 ATOM 7134 O OE1 . GLN B 1 380 ? -50.010 -41.567 23.392 1.00 104.43 ? 380 GLN B OE1 1 ATOM 7135 N NE2 . GLN B 1 380 ? -49.359 -39.715 22.282 1.00 104.99 ? 380 GLN B NE2 1 ATOM 7136 N N . ARG B 1 381 ? -47.306 -43.013 25.014 1.00 102.90 ? 381 ARG B N 1 ATOM 7137 C CA . ARG B 1 381 ? -46.429 -42.629 26.141 1.00 102.20 ? 381 ARG B CA 1 ATOM 7138 C C . ARG B 1 381 ? -46.571 -43.547 27.362 1.00 101.11 ? 381 ARG B C 1 ATOM 7139 O O . ARG B 1 381 ? -47.664 -43.746 27.893 1.00 101.00 ? 381 ARG B O 1 ATOM 7140 C CB . ARG B 1 381 ? -46.671 -41.175 26.569 1.00 102.56 ? 381 ARG B CB 1 ATOM 7141 C CG . ARG B 1 381 ? -46.826 -40.162 25.423 1.00 104.29 ? 381 ARG B CG 1 ATOM 7142 C CD . ARG B 1 381 ? -46.692 -38.706 25.907 1.00 107.48 ? 381 ARG B CD 1 ATOM 7143 N NE . ARG B 1 381 ? -47.249 -38.519 27.253 1.00 110.51 ? 381 ARG B NE 1 ATOM 7144 C CZ . ARG B 1 381 ? -46.528 -38.435 28.375 1.00 111.73 ? 381 ARG B CZ 1 ATOM 7145 N NH1 . ARG B 1 381 ? -47.131 -38.282 29.550 1.00 112.14 ? 381 ARG B NH1 1 ATOM 7146 N NH2 . ARG B 1 381 ? -45.203 -38.515 28.332 1.00 112.37 ? 381 ARG B NH2 1 ATOM 7147 N N . PRO B 1 382 ? -45.445 -44.086 27.829 1.00 100.10 ? 382 PRO B N 1 ATOM 7148 C CA . PRO B 1 382 ? -45.393 -45.118 28.868 1.00 99.27 ? 382 PRO B CA 1 ATOM 7149 C C . PRO B 1 382 ? -46.027 -44.732 30.212 1.00 98.32 ? 382 PRO B C 1 ATOM 7150 O O . PRO B 1 382 ? -46.687 -45.562 30.836 1.00 98.15 ? 382 PRO B O 1 ATOM 7151 C CB . PRO B 1 382 ? -43.889 -45.373 29.040 1.00 99.35 ? 382 PRO B CB 1 ATOM 7152 C CG . PRO B 1 382 ? -43.249 -44.827 27.797 1.00 99.58 ? 382 PRO B CG 1 ATOM 7153 C CD . PRO B 1 382 ? -44.107 -43.692 27.355 1.00 99.99 ? 382 PRO B CD 1 ATOM 7154 N N . GLU B 1 383 ? -45.823 -43.491 30.655 1.00 97.33 ? 383 GLU B N 1 ATOM 7155 C CA . GLU B 1 383 ? -46.293 -43.047 31.983 1.00 96.26 ? 383 GLU B CA 1 ATOM 7156 C C . GLU B 1 383 ? -47.789 -42.749 32.041 1.00 94.92 ? 383 GLU B C 1 ATOM 7157 O O . GLU B 1 383 ? -48.346 -42.548 33.122 1.00 94.73 ? 383 GLU B O 1 ATOM 7158 C CB . GLU B 1 383 ? -45.515 -41.808 32.471 1.00 96.74 ? 383 GLU B CB 1 ATOM 7159 C CG . GLU B 1 383 ? -45.388 -40.678 31.444 1.00 97.81 ? 383 GLU B CG 1 ATOM 7160 C CD . GLU B 1 383 ? -44.396 -41.033 30.358 1.00 100.30 ? 383 GLU B CD 1 ATOM 7161 O OE1 . GLU B 1 383 ? -44.701 -40.804 29.166 1.00 101.70 ? 383 GLU B OE1 1 ATOM 7162 O OE2 . GLU B 1 383 ? -43.319 -41.578 30.703 1.00 100.76 ? 383 GLU B OE2 1 ATOM 7163 N N . ASN B 1 384 ? -48.428 -42.710 30.874 1.00 93.19 ? 384 ASN B N 1 ATOM 7164 C CA . ASN B 1 384 ? -49.825 -42.321 30.781 1.00 91.22 ? 384 ASN B CA 1 ATOM 7165 C C . ASN B 1 384 ? -50.629 -42.781 31.975 1.00 89.80 ? 384 ASN B C 1 ATOM 7166 O O . ASN B 1 384 ? -51.071 -41.972 32.792 1.00 89.58 ? 384 ASN B O 1 ATOM 7167 C CB . ASN B 1 384 ? -50.435 -42.832 29.483 1.00 91.24 ? 384 ASN B CB 1 ATOM 7168 C CG . ASN B 1 384 ? -50.147 -41.913 28.327 1.00 91.51 ? 384 ASN B CG 1 ATOM 7169 O OD1 . ASN B 1 384 ? -49.555 -40.850 28.510 1.00 90.84 ? 384 ASN B OD1 1 ATOM 7170 N ND2 . ASN B 1 384 ? -50.563 -42.306 27.126 1.00 92.52 ? 384 ASN B ND2 1 ATOM 7171 N N . TYR B 1 385 ? -50.801 -44.089 32.083 1.00 88.08 ? 385 TYR B N 1 ATOM 7172 C CA . TYR B 1 385 ? -51.640 -44.634 33.128 1.00 86.57 ? 385 TYR B CA 1 ATOM 7173 C C . TYR B 1 385 ? -51.134 -44.269 34.522 1.00 85.33 ? 385 TYR B C 1 ATOM 7174 O O . TYR B 1 385 ? -51.927 -44.067 35.431 1.00 85.56 ? 385 TYR B O 1 ATOM 7175 C CB . TYR B 1 385 ? -51.793 -46.151 32.990 1.00 86.80 ? 385 TYR B CB 1 ATOM 7176 C CG . TYR B 1 385 ? -52.630 -46.611 31.805 1.00 87.26 ? 385 TYR B CG 1 ATOM 7177 C CD1 . TYR B 1 385 ? -54.023 -46.569 31.843 1.00 87.80 ? 385 TYR B CD1 1 ATOM 7178 C CD2 . TYR B 1 385 ? -52.024 -47.118 30.661 1.00 87.68 ? 385 TYR B CD2 1 ATOM 7179 C CE1 . TYR B 1 385 ? -54.788 -47.003 30.756 1.00 87.87 ? 385 TYR B CE1 1 ATOM 7180 C CE2 . TYR B 1 385 ? -52.774 -47.550 29.579 1.00 88.13 ? 385 TYR B CE2 1 ATOM 7181 C CZ . TYR B 1 385 ? -54.147 -47.491 29.630 1.00 88.26 ? 385 TYR B CZ 1 ATOM 7182 O OH . TYR B 1 385 ? -54.854 -47.933 28.542 1.00 88.88 ? 385 TYR B OH 1 ATOM 7183 N N . ARG B 1 386 ? -49.823 -44.171 34.705 1.00 83.60 ? 386 ARG B N 1 ATOM 7184 C CA . ARG B 1 386 ? -49.299 -43.755 36.016 1.00 81.64 ? 386 ARG B CA 1 ATOM 7185 C C . ARG B 1 386 ? -49.812 -42.369 36.435 1.00 80.52 ? 386 ARG B C 1 ATOM 7186 O O . ARG B 1 386 ? -50.266 -42.159 37.567 1.00 80.36 ? 386 ARG B O 1 ATOM 7187 C CB . ARG B 1 386 ? -47.767 -43.741 36.029 1.00 81.58 ? 386 ARG B CB 1 ATOM 7188 C CG . ARG B 1 386 ? -47.184 -43.307 37.373 1.00 80.37 ? 386 ARG B CG 1 ATOM 7189 C CD . ARG B 1 386 ? -45.684 -43.116 37.312 1.00 78.67 ? 386 ARG B CD 1 ATOM 7190 N NE . ARG B 1 386 ? -45.324 -41.944 36.517 1.00 78.21 ? 386 ARG B NE 1 ATOM 7191 C CZ . ARG B 1 386 ? -44.097 -41.695 36.066 1.00 77.67 ? 386 ARG B CZ 1 ATOM 7192 N NH1 . ARG B 1 386 ? -43.103 -42.541 36.330 1.00 77.41 ? 386 ARG B NH1 1 ATOM 7193 N NH2 . ARG B 1 386 ? -43.870 -40.609 35.341 1.00 76.81 ? 386 ARG B NH2 1 ATOM 7194 N N . GLU B 1 387 ? -49.726 -41.424 35.510 1.00 78.80 ? 387 GLU B N 1 ATOM 7195 C CA . GLU B 1 387 ? -50.072 -40.053 35.809 1.00 77.15 ? 387 GLU B CA 1 ATOM 7196 C C . GLU B 1 387 ? -51.568 -39.920 35.925 1.00 75.50 ? 387 GLU B C 1 ATOM 7197 O O . GLU B 1 387 ? -52.082 -39.251 36.825 1.00 75.46 ? 387 GLU B O 1 ATOM 7198 C CB . GLU B 1 387 ? -49.528 -39.143 34.722 1.00 77.35 ? 387 GLU B CB 1 ATOM 7199 C CG . GLU B 1 387 ? -48.024 -39.227 34.638 1.00 79.19 ? 387 GLU B CG 1 ATOM 7200 C CD . GLU B 1 387 ? -47.446 -38.253 33.642 1.00 82.24 ? 387 GLU B CD 1 ATOM 7201 O OE1 . GLU B 1 387 ? -46.303 -37.788 33.868 1.00 82.96 ? 387 GLU B OE1 1 ATOM 7202 O OE2 . GLU B 1 387 ? -48.143 -37.951 32.644 1.00 82.89 ? 387 GLU B OE2 1 ATOM 7203 N N . ALA B 1 388 ? -52.261 -40.583 35.012 1.00 73.29 ? 388 ALA B N 1 ATOM 7204 C CA . ALA B 1 388 ? -53.696 -40.595 35.048 1.00 71.26 ? 388 ALA B CA 1 ATOM 7205 C C . ALA B 1 388 ? -54.183 -40.940 36.449 1.00 69.98 ? 388 ALA B C 1 ATOM 7206 O O . ALA B 1 388 ? -54.956 -40.193 37.045 1.00 69.85 ? 388 ALA B O 1 ATOM 7207 C CB . ALA B 1 388 ? -54.216 -41.576 34.064 1.00 71.46 ? 388 ALA B CB 1 ATOM 7208 N N . LEU B 1 389 ? -53.729 -42.063 36.990 1.00 68.44 ? 389 LEU B N 1 ATOM 7209 C CA . LEU B 1 389 ? -54.263 -42.509 38.268 1.00 66.94 ? 389 LEU B CA 1 ATOM 7210 C C . LEU B 1 389 ? -53.947 -41.515 39.359 1.00 66.10 ? 389 LEU B C 1 ATOM 7211 O O . LEU B 1 389 ? -54.729 -41.353 40.299 1.00 66.04 ? 389 LEU B O 1 ATOM 7212 C CB . LEU B 1 389 ? -53.775 -43.905 38.652 1.00 66.74 ? 389 LEU B CB 1 ATOM 7213 C CG . LEU B 1 389 ? -54.311 -44.348 40.026 1.00 66.02 ? 389 LEU B CG 1 ATOM 7214 C CD1 . LEU B 1 389 ? -55.811 -44.368 40.096 1.00 64.89 ? 389 LEU B CD1 1 ATOM 7215 C CD2 . LEU B 1 389 ? -53.802 -45.731 40.368 1.00 66.01 ? 389 LEU B CD2 1 ATOM 7216 N N . GLY B 1 390 ? -52.815 -40.832 39.217 1.00 65.00 ? 390 GLY B N 1 ATOM 7217 C CA . GLY B 1 390 ? -52.433 -39.797 40.169 1.00 63.82 ? 390 GLY B CA 1 ATOM 7218 C C . GLY B 1 390 ? -53.456 -38.674 40.197 1.00 62.99 ? 390 GLY B C 1 ATOM 7219 O O . GLY B 1 390 ? -54.040 -38.366 41.248 1.00 62.69 ? 390 GLY B O 1 ATOM 7220 N N . ASP B 1 391 ? -53.665 -38.071 39.023 1.00 62.19 ? 391 ASP B N 1 ATOM 7221 C CA . ASP B 1 391 ? -54.682 -37.030 38.818 1.00 61.36 ? 391 ASP B CA 1 ATOM 7222 C C . ASP B 1 391 ? -56.073 -37.444 39.308 1.00 60.47 ? 391 ASP B C 1 ATOM 7223 O O . ASP B 1 391 ? -56.797 -36.652 39.920 1.00 60.11 ? 391 ASP B O 1 ATOM 7224 C CB . ASP B 1 391 ? -54.759 -36.667 37.339 1.00 61.35 ? 391 ASP B CB 1 ATOM 7225 C CG . ASP B 1 391 ? -53.614 -35.824 36.909 1.00 62.42 ? 391 ASP B CG 1 ATOM 7226 O OD1 . ASP B 1 391 ? -53.344 -34.851 37.630 1.00 63.50 ? 391 ASP B OD1 1 ATOM 7227 O OD2 . ASP B 1 391 ? -52.983 -36.133 35.873 1.00 63.47 ? 391 ASP B OD2 1 ATOM 7228 N N . VAL B 1 392 ? -56.449 -38.682 39.028 1.00 59.32 ? 392 VAL B N 1 ATOM 7229 C CA . VAL B 1 392 ? -57.737 -39.132 39.455 1.00 58.68 ? 392 VAL B CA 1 ATOM 7230 C C . VAL B 1 392 ? -57.903 -38.894 40.942 1.00 58.68 ? 392 VAL B C 1 ATOM 7231 O O . VAL B 1 392 ? -58.892 -38.295 41.406 1.00 58.40 ? 392 VAL B O 1 ATOM 7232 C CB . VAL B 1 392 ? -57.916 -40.582 39.138 1.00 58.63 ? 392 VAL B CB 1 ATOM 7233 C CG1 . VAL B 1 392 ? -59.168 -41.143 39.847 1.00 57.87 ? 392 VAL B CG1 1 ATOM 7234 C CG2 . VAL B 1 392 ? -58.026 -40.713 37.643 1.00 58.51 ? 392 VAL B CG2 1 ATOM 7235 N N . VAL B 1 393 ? -56.916 -39.348 41.696 1.00 58.47 ? 393 VAL B N 1 ATOM 7236 C CA . VAL B 1 393 ? -56.956 -39.184 43.137 1.00 58.19 ? 393 VAL B CA 1 ATOM 7237 C C . VAL B 1 393 ? -56.796 -37.708 43.519 1.00 58.22 ? 393 VAL B C 1 ATOM 7238 O O . VAL B 1 393 ? -57.495 -37.197 44.413 1.00 58.11 ? 393 VAL B O 1 ATOM 7239 C CB . VAL B 1 393 ? -55.892 -40.075 43.797 1.00 58.16 ? 393 VAL B CB 1 ATOM 7240 C CG1 . VAL B 1 393 ? -55.913 -39.940 45.339 1.00 57.66 ? 393 VAL B CG1 1 ATOM 7241 C CG2 . VAL B 1 393 ? -56.110 -41.522 43.352 1.00 57.34 ? 393 VAL B CG2 1 ATOM 7242 N N . GLY B 1 394 ? -55.883 -37.033 42.824 1.00 57.85 ? 394 GLY B N 1 ATOM 7243 C CA . GLY B 1 394 ? -55.648 -35.630 43.058 1.00 57.84 ? 394 GLY B CA 1 ATOM 7244 C C . GLY B 1 394 ? -56.944 -34.872 42.875 1.00 58.02 ? 394 GLY B C 1 ATOM 7245 O O . GLY B 1 394 ? -57.466 -34.247 43.812 1.00 58.40 ? 394 GLY B O 1 ATOM 7246 N N . ASP B 1 395 ? -57.478 -34.954 41.661 1.00 57.98 ? 395 ASP B N 1 ATOM 7247 C CA . ASP B 1 395 ? -58.639 -34.171 41.262 1.00 57.59 ? 395 ASP B CA 1 ATOM 7248 C C . ASP B 1 395 ? -59.838 -34.512 42.114 1.00 57.44 ? 395 ASP B C 1 ATOM 7249 O O . ASP B 1 395 ? -60.549 -33.631 42.566 1.00 57.99 ? 395 ASP B O 1 ATOM 7250 C CB . ASP B 1 395 ? -58.953 -34.405 39.789 1.00 57.32 ? 395 ASP B CB 1 ATOM 7251 C CG . ASP B 1 395 ? -57.825 -33.991 38.900 1.00 57.66 ? 395 ASP B CG 1 ATOM 7252 O OD1 . ASP B 1 395 ? -57.883 -34.259 37.685 1.00 58.35 ? 395 ASP B OD1 1 ATOM 7253 O OD2 . ASP B 1 395 ? -56.870 -33.387 39.425 1.00 58.30 ? 395 ASP B OD2 1 ATOM 7254 N N . TYR B 1 396 ? -60.066 -35.790 42.350 1.00 57.08 ? 396 TYR B N 1 ATOM 7255 C CA . TYR B 1 396 ? -61.266 -36.173 43.067 1.00 57.15 ? 396 TYR B CA 1 ATOM 7256 C C . TYR B 1 396 ? -61.267 -35.805 44.566 1.00 57.26 ? 396 TYR B C 1 ATOM 7257 O O . TYR B 1 396 ? -62.290 -35.349 45.099 1.00 57.27 ? 396 TYR B O 1 ATOM 7258 C CB . TYR B 1 396 ? -61.516 -37.660 42.888 1.00 56.91 ? 396 TYR B CB 1 ATOM 7259 C CG . TYR B 1 396 ? -62.546 -38.264 43.837 1.00 57.12 ? 396 TYR B CG 1 ATOM 7260 C CD1 . TYR B 1 396 ? -63.887 -37.859 43.816 1.00 57.21 ? 396 TYR B CD1 1 ATOM 7261 C CD2 . TYR B 1 396 ? -62.187 -39.280 44.716 1.00 56.63 ? 396 TYR B CD2 1 ATOM 7262 C CE1 . TYR B 1 396 ? -64.829 -38.443 44.662 1.00 56.16 ? 396 TYR B CE1 1 ATOM 7263 C CE2 . TYR B 1 396 ? -63.118 -39.860 45.562 1.00 56.62 ? 396 TYR B CE2 1 ATOM 7264 C CZ . TYR B 1 396 ? -64.435 -39.444 45.527 1.00 56.28 ? 396 TYR B CZ 1 ATOM 7265 O OH . TYR B 1 396 ? -65.338 -40.037 46.373 1.00 55.72 ? 396 TYR B OH 1 ATOM 7266 N N . ASN B 1 397 ? -60.128 -35.995 45.237 1.00 57.25 ? 397 ASN B N 1 ATOM 7267 C CA . ASN B 1 397 ? -60.081 -35.848 46.687 1.00 57.03 ? 397 ASN B CA 1 ATOM 7268 C C . ASN B 1 397 ? -59.742 -34.462 47.152 1.00 57.05 ? 397 ASN B C 1 ATOM 7269 O O . ASN B 1 397 ? -60.069 -34.095 48.299 1.00 56.38 ? 397 ASN B O 1 ATOM 7270 C CB . ASN B 1 397 ? -59.070 -36.799 47.278 1.00 56.85 ? 397 ASN B CB 1 ATOM 7271 C CG . ASN B 1 397 ? -59.462 -38.232 47.092 1.00 56.82 ? 397 ASN B CG 1 ATOM 7272 O OD1 . ASN B 1 397 ? -60.334 -38.764 47.804 1.00 55.59 ? 397 ASN B OD1 1 ATOM 7273 N ND2 . ASN B 1 397 ? -58.812 -38.887 46.136 1.00 56.07 ? 397 ASN B ND2 1 ATOM 7274 N N . PHE B 1 398 ? -59.089 -33.701 46.264 1.00 56.81 ? 398 PHE B N 1 ATOM 7275 C CA . PHE B 1 398 ? -58.506 -32.434 46.664 1.00 56.75 ? 398 PHE B CA 1 ATOM 7276 C C . PHE B 1 398 ? -58.804 -31.277 45.749 1.00 56.76 ? 398 PHE B C 1 ATOM 7277 O O . PHE B 1 398 ? -59.514 -30.327 46.131 1.00 57.05 ? 398 PHE B O 1 ATOM 7278 C CB . PHE B 1 398 ? -57.007 -32.599 46.838 1.00 56.96 ? 398 PHE B CB 1 ATOM 7279 C CG . PHE B 1 398 ? -56.644 -33.476 48.009 1.00 57.70 ? 398 PHE B CG 1 ATOM 7280 C CD1 . PHE B 1 398 ? -56.063 -34.718 47.805 1.00 57.27 ? 398 PHE B CD1 1 ATOM 7281 C CD2 . PHE B 1 398 ? -56.930 -33.071 49.312 1.00 57.00 ? 398 PHE B CD2 1 ATOM 7282 C CE1 . PHE B 1 398 ? -55.760 -35.521 48.877 1.00 57.54 ? 398 PHE B CE1 1 ATOM 7283 C CE2 . PHE B 1 398 ? -56.633 -33.881 50.382 1.00 58.10 ? 398 PHE B CE2 1 ATOM 7284 C CZ . PHE B 1 398 ? -56.042 -35.102 50.171 1.00 57.94 ? 398 PHE B CZ 1 ATOM 7285 N N . ILE B 1 399 ? -58.277 -31.346 44.534 1.00 56.45 ? 399 ILE B N 1 ATOM 7286 C CA . ILE B 1 399 ? -58.381 -30.200 43.645 1.00 55.90 ? 399 ILE B CA 1 ATOM 7287 C C . ILE B 1 399 ? -59.803 -29.753 43.293 1.00 55.45 ? 399 ILE B C 1 ATOM 7288 O O . ILE B 1 399 ? -60.100 -28.569 43.279 1.00 55.34 ? 399 ILE B O 1 ATOM 7289 C CB . ILE B 1 399 ? -57.528 -30.378 42.425 1.00 55.87 ? 399 ILE B CB 1 ATOM 7290 C CG1 . ILE B 1 399 ? -56.093 -30.583 42.886 1.00 56.56 ? 399 ILE B CG1 1 ATOM 7291 C CG2 . ILE B 1 399 ? -57.585 -29.126 41.565 1.00 55.78 ? 399 ILE B CG2 1 ATOM 7292 C CD1 . ILE B 1 399 ? -55.122 -30.961 41.776 1.00 58.91 ? 399 ILE B CD1 1 ATOM 7293 N N . CYS B 1 400 ? -60.697 -30.680 43.037 1.00 55.12 ? 400 CYS B N 1 ATOM 7294 C CA . CYS B 1 400 ? -62.039 -30.256 42.710 1.00 55.63 ? 400 CYS B CA 1 ATOM 7295 C C . CYS B 1 400 ? -62.825 -29.752 43.904 1.00 55.15 ? 400 CYS B C 1 ATOM 7296 O O . CYS B 1 400 ? -63.405 -28.656 43.848 1.00 54.95 ? 400 CYS B O 1 ATOM 7297 C CB . CYS B 1 400 ? -62.792 -31.356 41.990 1.00 55.87 ? 400 CYS B CB 1 ATOM 7298 S SG . CYS B 1 400 ? -61.986 -31.740 40.425 1.00 59.91 ? 400 CYS B SG 1 ATOM 7299 N N . PRO B 1 401 ? -62.850 -30.538 44.996 1.00 54.71 ? 401 PRO B N 1 ATOM 7300 C CA . PRO B 1 401 ? -63.705 -30.046 46.074 1.00 54.31 ? 401 PRO B CA 1 ATOM 7301 C C . PRO B 1 401 ? -63.149 -28.707 46.559 1.00 54.06 ? 401 PRO B C 1 ATOM 7302 O O . PRO B 1 401 ? -63.899 -27.837 47.023 1.00 53.44 ? 401 PRO B O 1 ATOM 7303 C CB . PRO B 1 401 ? -63.605 -31.137 47.150 1.00 54.13 ? 401 PRO B CB 1 ATOM 7304 C CG . PRO B 1 401 ? -63.040 -32.343 46.428 1.00 54.57 ? 401 PRO B CG 1 ATOM 7305 C CD . PRO B 1 401 ? -62.179 -31.805 45.331 1.00 54.35 ? 401 PRO B CD 1 ATOM 7306 N N . ALA B 1 402 ? -61.834 -28.555 46.424 1.00 53.87 ? 402 ALA B N 1 ATOM 7307 C CA . ALA B 1 402 ? -61.164 -27.333 46.810 1.00 53.84 ? 402 ALA B CA 1 ATOM 7308 C C . ALA B 1 402 ? -61.750 -26.212 45.987 1.00 54.00 ? 402 ALA B C 1 ATOM 7309 O O . ALA B 1 402 ? -62.295 -25.251 46.522 1.00 54.06 ? 402 ALA B O 1 ATOM 7310 C CB . ALA B 1 402 ? -59.672 -27.451 46.553 1.00 53.65 ? 402 ALA B CB 1 ATOM 7311 N N . LEU B 1 403 ? -61.649 -26.362 44.671 1.00 53.98 ? 403 LEU B N 1 ATOM 7312 C CA . LEU B 1 403 ? -62.118 -25.350 43.758 1.00 53.79 ? 403 LEU B CA 1 ATOM 7313 C C . LEU B 1 403 ? -63.582 -25.072 44.030 1.00 54.41 ? 403 LEU B C 1 ATOM 7314 O O . LEU B 1 403 ? -63.969 -23.925 44.267 1.00 54.34 ? 403 LEU B O 1 ATOM 7315 C CB . LEU B 1 403 ? -61.912 -25.796 42.313 1.00 53.35 ? 403 LEU B CB 1 ATOM 7316 C CG . LEU B 1 403 ? -60.519 -25.559 41.748 1.00 52.20 ? 403 LEU B CG 1 ATOM 7317 C CD1 . LEU B 1 403 ? -60.294 -26.347 40.471 1.00 51.89 ? 403 LEU B CD1 1 ATOM 7318 C CD2 . LEU B 1 403 ? -60.360 -24.095 41.502 1.00 51.23 ? 403 LEU B CD2 1 ATOM 7319 N N . GLU B 1 404 ? -64.392 -26.129 44.032 1.00 55.31 ? 404 GLU B N 1 ATOM 7320 C CA . GLU B 1 404 ? -65.846 -25.984 44.183 1.00 56.38 ? 404 GLU B CA 1 ATOM 7321 C C . GLU B 1 404 ? -66.228 -25.226 45.456 1.00 56.10 ? 404 GLU B C 1 ATOM 7322 O O . GLU B 1 404 ? -67.100 -24.382 45.430 1.00 56.50 ? 404 GLU B O 1 ATOM 7323 C CB . GLU B 1 404 ? -66.517 -27.348 44.139 1.00 56.84 ? 404 GLU B CB 1 ATOM 7324 C CG . GLU B 1 404 ? -68.016 -27.323 44.370 1.00 61.10 ? 404 GLU B CG 1 ATOM 7325 C CD . GLU B 1 404 ? -68.807 -26.907 43.125 1.00 66.16 ? 404 GLU B CD 1 ATOM 7326 O OE1 . GLU B 1 404 ? -68.196 -26.359 42.184 1.00 67.93 ? 404 GLU B OE1 1 ATOM 7327 O OE2 . GLU B 1 404 ? -70.046 -27.130 43.088 1.00 68.09 ? 404 GLU B OE2 1 ATOM 7328 N N . PHE B 1 405 ? -65.567 -25.513 46.568 1.00 55.99 ? 405 PHE B N 1 ATOM 7329 C CA . PHE B 1 405 ? -65.749 -24.703 47.767 1.00 55.73 ? 405 PHE B CA 1 ATOM 7330 C C . PHE B 1 405 ? -65.536 -23.211 47.526 1.00 55.80 ? 405 PHE B C 1 ATOM 7331 O O . PHE B 1 405 ? -66.406 -22.392 47.842 1.00 55.88 ? 405 PHE B O 1 ATOM 7332 C CB . PHE B 1 405 ? -64.803 -25.169 48.873 1.00 55.65 ? 405 PHE B CB 1 ATOM 7333 C CG . PHE B 1 405 ? -64.867 -24.329 50.104 1.00 54.36 ? 405 PHE B CG 1 ATOM 7334 C CD1 . PHE B 1 405 ? -65.803 -24.588 51.079 1.00 53.56 ? 405 PHE B CD1 1 ATOM 7335 C CD2 . PHE B 1 405 ? -64.007 -23.265 50.276 1.00 53.98 ? 405 PHE B CD2 1 ATOM 7336 C CE1 . PHE B 1 405 ? -65.867 -23.806 52.217 1.00 53.40 ? 405 PHE B CE1 1 ATOM 7337 C CE2 . PHE B 1 405 ? -64.063 -22.483 51.402 1.00 53.41 ? 405 PHE B CE2 1 ATOM 7338 C CZ . PHE B 1 405 ? -64.998 -22.760 52.378 1.00 53.49 ? 405 PHE B CZ 1 ATOM 7339 N N . THR B 1 406 ? -64.367 -22.865 46.994 1.00 55.91 ? 406 THR B N 1 ATOM 7340 C CA . THR B 1 406 ? -64.017 -21.466 46.728 1.00 56.27 ? 406 THR B CA 1 ATOM 7341 C C . THR B 1 406 ? -65.110 -20.824 45.908 1.00 56.96 ? 406 THR B C 1 ATOM 7342 O O . THR B 1 406 ? -65.635 -19.762 46.256 1.00 57.41 ? 406 THR B O 1 ATOM 7343 C CB . THR B 1 406 ? -62.728 -21.345 45.911 1.00 55.97 ? 406 THR B CB 1 ATOM 7344 O OG1 . THR B 1 406 ? -61.715 -22.164 46.493 1.00 56.63 ? 406 THR B OG1 1 ATOM 7345 C CG2 . THR B 1 406 ? -62.258 -19.947 45.900 1.00 54.87 ? 406 THR B CG2 1 ATOM 7346 N N . LYS B 1 407 ? -65.457 -21.487 44.812 1.00 57.25 ? 407 LYS B N 1 ATOM 7347 C CA . LYS B 1 407 ? -66.494 -21.017 43.934 1.00 57.48 ? 407 LYS B CA 1 ATOM 7348 C C . LYS B 1 407 ? -67.745 -20.659 44.701 1.00 56.96 ? 407 LYS B C 1 ATOM 7349 O O . LYS B 1 407 ? -68.152 -19.518 44.688 1.00 56.81 ? 407 LYS B O 1 ATOM 7350 C CB . LYS B 1 407 ? -66.791 -22.089 42.902 1.00 58.03 ? 407 LYS B CB 1 ATOM 7351 C CG . LYS B 1 407 ? -67.407 -21.554 41.654 1.00 60.35 ? 407 LYS B CG 1 ATOM 7352 C CD . LYS B 1 407 ? -67.777 -22.697 40.704 1.00 64.98 ? 407 LYS B CD 1 ATOM 7353 C CE . LYS B 1 407 ? -68.716 -22.220 39.564 1.00 67.42 ? 407 LYS B CE 1 ATOM 7354 N NZ . LYS B 1 407 ? -69.556 -21.004 39.932 1.00 67.93 ? 407 LYS B NZ 1 ATOM 7355 N N . LYS B 1 408 ? -68.326 -21.622 45.406 1.00 57.11 ? 408 LYS B N 1 ATOM 7356 C CA . LYS B 1 408 ? -69.612 -21.415 46.086 1.00 57.92 ? 408 LYS B CA 1 ATOM 7357 C C . LYS B 1 408 ? -69.535 -20.372 47.171 1.00 58.07 ? 408 LYS B C 1 ATOM 7358 O O . LYS B 1 408 ? -70.527 -19.713 47.494 1.00 57.80 ? 408 LYS B O 1 ATOM 7359 C CB . LYS B 1 408 ? -70.105 -22.698 46.734 1.00 58.12 ? 408 LYS B CB 1 ATOM 7360 C CG . LYS B 1 408 ? -70.176 -23.889 45.804 1.00 60.17 ? 408 LYS B CG 1 ATOM 7361 C CD . LYS B 1 408 ? -71.557 -24.135 45.255 1.00 63.13 ? 408 LYS B CD 1 ATOM 7362 C CE . LYS B 1 408 ? -71.804 -25.630 45.247 1.00 65.48 ? 408 LYS B CE 1 ATOM 7363 N NZ . LYS B 1 408 ? -73.113 -25.959 44.624 1.00 68.17 ? 408 LYS B NZ 1 ATOM 7364 N N . PHE B 1 409 ? -68.354 -20.255 47.762 1.00 58.62 ? 409 PHE B N 1 ATOM 7365 C CA . PHE B 1 409 ? -68.158 -19.353 48.885 1.00 58.76 ? 409 PHE B CA 1 ATOM 7366 C C . PHE B 1 409 ? -68.128 -17.905 48.404 1.00 59.85 ? 409 PHE B C 1 ATOM 7367 O O . PHE B 1 409 ? -68.691 -17.005 49.073 1.00 59.88 ? 409 PHE B O 1 ATOM 7368 C CB . PHE B 1 409 ? -66.858 -19.694 49.618 1.00 58.24 ? 409 PHE B CB 1 ATOM 7369 C CG . PHE B 1 409 ? -66.647 -18.889 50.872 1.00 55.68 ? 409 PHE B CG 1 ATOM 7370 C CD1 . PHE B 1 409 ? -67.168 -19.318 52.071 1.00 53.47 ? 409 PHE B CD1 1 ATOM 7371 C CD2 . PHE B 1 409 ? -65.941 -17.712 50.844 1.00 52.86 ? 409 PHE B CD2 1 ATOM 7372 C CE1 . PHE B 1 409 ? -66.976 -18.594 53.220 1.00 52.48 ? 409 PHE B CE1 1 ATOM 7373 C CE2 . PHE B 1 409 ? -65.763 -16.981 51.969 1.00 51.98 ? 409 PHE B CE2 1 ATOM 7374 C CZ . PHE B 1 409 ? -66.277 -17.417 53.168 1.00 52.71 ? 409 PHE B CZ 1 ATOM 7375 N N . SER B 1 410 ? -67.468 -17.689 47.256 1.00 60.56 ? 410 SER B N 1 ATOM 7376 C CA . SER B 1 410 ? -67.314 -16.351 46.720 1.00 61.73 ? 410 SER B CA 1 ATOM 7377 C C . SER B 1 410 ? -68.628 -15.902 46.137 1.00 62.52 ? 410 SER B C 1 ATOM 7378 O O . SER B 1 410 ? -68.853 -14.723 45.921 1.00 62.74 ? 410 SER B O 1 ATOM 7379 C CB . SER B 1 410 ? -66.250 -16.314 45.638 1.00 61.70 ? 410 SER B CB 1 ATOM 7380 O OG . SER B 1 410 ? -66.638 -17.118 44.545 1.00 62.17 ? 410 SER B OG 1 ATOM 7381 N N . GLU B 1 411 ? -69.509 -16.842 45.860 1.00 63.59 ? 411 GLU B N 1 ATOM 7382 C CA . GLU B 1 411 ? -70.785 -16.427 45.332 1.00 64.92 ? 411 GLU B CA 1 ATOM 7383 C C . GLU B 1 411 ? -71.521 -15.544 46.313 1.00 65.42 ? 411 GLU B C 1 ATOM 7384 O O . GLU B 1 411 ? -72.320 -14.725 45.909 1.00 65.90 ? 411 GLU B O 1 ATOM 7385 C CB . GLU B 1 411 ? -71.651 -17.607 44.910 1.00 64.91 ? 411 GLU B CB 1 ATOM 7386 C CG . GLU B 1 411 ? -71.543 -17.890 43.442 1.00 66.50 ? 411 GLU B CG 1 ATOM 7387 C CD . GLU B 1 411 ? -71.756 -19.343 43.126 1.00 69.35 ? 411 GLU B CD 1 ATOM 7388 O OE1 . GLU B 1 411 ? -72.445 -20.038 43.902 1.00 70.46 ? 411 GLU B OE1 1 ATOM 7389 O OE2 . GLU B 1 411 ? -71.231 -19.804 42.095 1.00 71.61 ? 411 GLU B OE2 1 ATOM 7390 N N . TRP B 1 412 ? -71.255 -15.678 47.601 1.00 66.00 ? 412 TRP B N 1 ATOM 7391 C CA . TRP B 1 412 ? -72.036 -14.907 48.547 1.00 66.39 ? 412 TRP B CA 1 ATOM 7392 C C . TRP B 1 412 ? -71.411 -13.552 48.874 1.00 66.54 ? 412 TRP B C 1 ATOM 7393 O O . TRP B 1 412 ? -71.714 -12.919 49.881 1.00 66.91 ? 412 TRP B O 1 ATOM 7394 C CB . TRP B 1 412 ? -72.354 -15.752 49.766 1.00 66.59 ? 412 TRP B CB 1 ATOM 7395 C CG . TRP B 1 412 ? -73.374 -16.781 49.428 1.00 67.64 ? 412 TRP B CG 1 ATOM 7396 C CD1 . TRP B 1 412 ? -73.163 -17.984 48.797 1.00 67.87 ? 412 TRP B CD1 1 ATOM 7397 C CD2 . TRP B 1 412 ? -74.784 -16.694 49.670 1.00 69.01 ? 412 TRP B CD2 1 ATOM 7398 N NE1 . TRP B 1 412 ? -74.357 -18.656 48.653 1.00 68.71 ? 412 TRP B NE1 1 ATOM 7399 C CE2 . TRP B 1 412 ? -75.369 -17.881 49.170 1.00 69.70 ? 412 TRP B CE2 1 ATOM 7400 C CE3 . TRP B 1 412 ? -75.610 -15.733 50.272 1.00 68.92 ? 412 TRP B CE3 1 ATOM 7401 C CZ2 . TRP B 1 412 ? -76.744 -18.124 49.253 1.00 69.70 ? 412 TRP B CZ2 1 ATOM 7402 C CZ3 . TRP B 1 412 ? -76.972 -15.976 50.350 1.00 68.70 ? 412 TRP B CZ3 1 ATOM 7403 C CH2 . TRP B 1 412 ? -77.523 -17.160 49.853 1.00 69.35 ? 412 TRP B CH2 1 ATOM 7404 N N . GLY B 1 413 ? -70.536 -13.104 47.990 1.00 66.59 ? 413 GLY B N 1 ATOM 7405 C CA . GLY B 1 413 ? -70.046 -11.748 48.045 1.00 66.51 ? 413 GLY B CA 1 ATOM 7406 C C . GLY B 1 413 ? -68.741 -11.547 48.767 1.00 66.55 ? 413 GLY B C 1 ATOM 7407 O O . GLY B 1 413 ? -68.434 -10.445 49.162 1.00 67.19 ? 413 GLY B O 1 ATOM 7408 N N . ASN B 1 414 ? -67.950 -12.592 48.952 1.00 66.51 ? 414 ASN B N 1 ATOM 7409 C CA . ASN B 1 414 ? -66.693 -12.429 49.691 1.00 66.18 ? 414 ASN B CA 1 ATOM 7410 C C . ASN B 1 414 ? -65.476 -12.530 48.788 1.00 65.59 ? 414 ASN B C 1 ATOM 7411 O O . ASN B 1 414 ? -65.515 -13.183 47.741 1.00 65.56 ? 414 ASN B O 1 ATOM 7412 C CB . ASN B 1 414 ? -66.588 -13.453 50.817 1.00 66.33 ? 414 ASN B CB 1 ATOM 7413 C CG . ASN B 1 414 ? -67.814 -13.468 51.696 1.00 67.87 ? 414 ASN B CG 1 ATOM 7414 O OD1 . ASN B 1 414 ? -67.928 -12.669 52.632 1.00 70.17 ? 414 ASN B OD1 1 ATOM 7415 N ND2 . ASN B 1 414 ? -68.746 -14.378 51.407 1.00 68.71 ? 414 ASN B ND2 1 ATOM 7416 N N . ASN B 1 415 ? -64.389 -11.895 49.201 1.00 64.79 ? 415 ASN B N 1 ATOM 7417 C CA . ASN B 1 415 ? -63.155 -11.988 48.458 1.00 63.93 ? 415 ASN B CA 1 ATOM 7418 C C . ASN B 1 415 ? -62.437 -13.266 48.746 1.00 63.21 ? 415 ASN B C 1 ATOM 7419 O O . ASN B 1 415 ? -62.225 -13.623 49.901 1.00 63.53 ? 415 ASN B O 1 ATOM 7420 C CB . ASN B 1 415 ? -62.240 -10.846 48.811 1.00 64.34 ? 415 ASN B CB 1 ATOM 7421 C CG . ASN B 1 415 ? -62.584 -9.621 48.072 1.00 64.99 ? 415 ASN B CG 1 ATOM 7422 O OD1 . ASN B 1 415 ? -63.581 -9.590 47.350 1.00 67.02 ? 415 ASN B OD1 1 ATOM 7423 N ND2 . ASN B 1 415 ? -61.776 -8.591 48.232 1.00 65.85 ? 415 ASN B ND2 1 ATOM 7424 N N . ALA B 1 416 ? -62.042 -13.952 47.690 1.00 61.96 ? 416 ALA B N 1 ATOM 7425 C CA . ALA B 1 416 ? -61.382 -15.215 47.849 1.00 61.10 ? 416 ALA B CA 1 ATOM 7426 C C . ALA B 1 416 ? -60.216 -15.201 46.903 1.00 60.60 ? 416 ALA B C 1 ATOM 7427 O O . ALA B 1 416 ? -60.319 -14.649 45.812 1.00 60.84 ? 416 ALA B O 1 ATOM 7428 C CB . ALA B 1 416 ? -62.336 -16.333 47.500 1.00 60.89 ? 416 ALA B CB 1 ATOM 7429 N N . PHE B 1 417 ? -59.099 -15.786 47.314 1.00 59.86 ? 417 PHE B N 1 ATOM 7430 C CA . PHE B 1 417 ? -57.946 -15.894 46.432 1.00 59.38 ? 417 PHE B CA 1 ATOM 7431 C C . PHE B 1 417 ? -57.538 -17.357 46.309 1.00 59.41 ? 417 PHE B C 1 ATOM 7432 O O . PHE B 1 417 ? -57.617 -18.125 47.298 1.00 59.71 ? 417 PHE B O 1 ATOM 7433 C CB . PHE B 1 417 ? -56.790 -15.067 46.977 1.00 59.12 ? 417 PHE B CB 1 ATOM 7434 C CG . PHE B 1 417 ? -57.150 -13.640 47.241 1.00 58.63 ? 417 PHE B CG 1 ATOM 7435 C CD1 . PHE B 1 417 ? -57.814 -13.279 48.413 1.00 57.87 ? 417 PHE B CD1 1 ATOM 7436 C CD2 . PHE B 1 417 ? -56.839 -12.654 46.312 1.00 57.10 ? 417 PHE B CD2 1 ATOM 7437 C CE1 . PHE B 1 417 ? -58.153 -11.967 48.660 1.00 56.63 ? 417 PHE B CE1 1 ATOM 7438 C CE2 . PHE B 1 417 ? -57.181 -11.342 46.552 1.00 56.20 ? 417 PHE B CE2 1 ATOM 7439 C CZ . PHE B 1 417 ? -57.845 -10.998 47.739 1.00 56.61 ? 417 PHE B CZ 1 ATOM 7440 N N . PHE B 1 418 ? -57.106 -17.756 45.115 1.00 58.69 ? 418 PHE B N 1 ATOM 7441 C CA . PHE B 1 418 ? -56.806 -19.154 44.905 1.00 58.46 ? 418 PHE B CA 1 ATOM 7442 C C . PHE B 1 418 ? -55.424 -19.317 44.322 1.00 59.04 ? 418 PHE B C 1 ATOM 7443 O O . PHE B 1 418 ? -55.032 -18.557 43.416 1.00 59.57 ? 418 PHE B O 1 ATOM 7444 C CB . PHE B 1 418 ? -57.839 -19.790 43.986 1.00 58.20 ? 418 PHE B CB 1 ATOM 7445 C CG . PHE B 1 418 ? -57.936 -21.286 44.126 1.00 57.64 ? 418 PHE B CG 1 ATOM 7446 C CD1 . PHE B 1 418 ? -57.092 -22.118 43.418 1.00 57.81 ? 418 PHE B CD1 1 ATOM 7447 C CD2 . PHE B 1 418 ? -58.892 -21.862 44.953 1.00 56.16 ? 418 PHE B CD2 1 ATOM 7448 C CE1 . PHE B 1 418 ? -57.199 -23.497 43.554 1.00 57.62 ? 418 PHE B CE1 1 ATOM 7449 C CE2 . PHE B 1 418 ? -59.003 -23.237 45.086 1.00 54.84 ? 418 PHE B CE2 1 ATOM 7450 C CZ . PHE B 1 418 ? -58.165 -24.048 44.402 1.00 56.26 ? 418 PHE B CZ 1 ATOM 7451 N N . TYR B 1 419 ? -54.686 -20.304 44.837 1.00 59.33 ? 419 TYR B N 1 ATOM 7452 C CA . TYR B 1 419 ? -53.319 -20.566 44.399 1.00 59.46 ? 419 TYR B CA 1 ATOM 7453 C C . TYR B 1 419 ? -53.153 -22.005 43.966 1.00 60.46 ? 419 TYR B C 1 ATOM 7454 O O . TYR B 1 419 ? -53.760 -22.937 44.528 1.00 60.58 ? 419 TYR B O 1 ATOM 7455 C CB . TYR B 1 419 ? -52.323 -20.273 45.523 1.00 59.08 ? 419 TYR B CB 1 ATOM 7456 C CG . TYR B 1 419 ? -52.335 -21.281 46.679 1.00 58.14 ? 419 TYR B CG 1 ATOM 7457 C CD1 . TYR B 1 419 ? -53.002 -20.997 47.850 1.00 56.29 ? 419 TYR B CD1 1 ATOM 7458 C CD2 . TYR B 1 419 ? -51.667 -22.515 46.586 1.00 56.74 ? 419 TYR B CD2 1 ATOM 7459 C CE1 . TYR B 1 419 ? -53.015 -21.897 48.898 1.00 56.31 ? 419 TYR B CE1 1 ATOM 7460 C CE2 . TYR B 1 419 ? -51.672 -23.427 47.629 1.00 54.67 ? 419 TYR B CE2 1 ATOM 7461 C CZ . TYR B 1 419 ? -52.350 -23.111 48.792 1.00 56.10 ? 419 TYR B CZ 1 ATOM 7462 O OH . TYR B 1 419 ? -52.391 -23.984 49.878 1.00 55.77 ? 419 TYR B OH 1 ATOM 7463 N N . TYR B 1 420 ? -52.293 -22.180 42.973 1.00 61.48 ? 420 TYR B N 1 ATOM 7464 C CA . TYR B 1 420 ? -51.919 -23.499 42.496 1.00 62.34 ? 420 TYR B CA 1 ATOM 7465 C C . TYR B 1 420 ? -50.422 -23.583 42.723 1.00 63.41 ? 420 TYR B C 1 ATOM 7466 O O . TYR B 1 420 ? -49.619 -23.044 41.942 1.00 63.61 ? 420 TYR B O 1 ATOM 7467 C CB . TYR B 1 420 ? -52.266 -23.616 41.014 1.00 61.97 ? 420 TYR B CB 1 ATOM 7468 C CG . TYR B 1 420 ? -52.067 -24.969 40.356 1.00 61.53 ? 420 TYR B CG 1 ATOM 7469 C CD1 . TYR B 1 420 ? -52.688 -26.124 40.843 1.00 60.30 ? 420 TYR B CD1 1 ATOM 7470 C CD2 . TYR B 1 420 ? -51.310 -25.075 39.186 1.00 61.23 ? 420 TYR B CD2 1 ATOM 7471 C CE1 . TYR B 1 420 ? -52.526 -27.358 40.189 1.00 59.65 ? 420 TYR B CE1 1 ATOM 7472 C CE2 . TYR B 1 420 ? -51.140 -26.298 38.532 1.00 59.90 ? 420 TYR B CE2 1 ATOM 7473 C CZ . TYR B 1 420 ? -51.746 -27.426 39.035 1.00 59.39 ? 420 TYR B CZ 1 ATOM 7474 O OH . TYR B 1 420 ? -51.555 -28.608 38.366 1.00 59.36 ? 420 TYR B OH 1 ATOM 7475 N N . PHE B 1 421 ? -50.059 -24.232 43.823 1.00 64.51 ? 421 PHE B N 1 ATOM 7476 C CA . PHE B 1 421 ? -48.667 -24.417 44.196 1.00 65.93 ? 421 PHE B CA 1 ATOM 7477 C C . PHE B 1 421 ? -48.017 -25.510 43.365 1.00 66.46 ? 421 PHE B C 1 ATOM 7478 O O . PHE B 1 421 ? -48.432 -26.682 43.440 1.00 66.41 ? 421 PHE B O 1 ATOM 7479 C CB . PHE B 1 421 ? -48.593 -24.802 45.673 1.00 66.40 ? 421 PHE B CB 1 ATOM 7480 C CG . PHE B 1 421 ? -47.189 -24.930 46.204 1.00 68.19 ? 421 PHE B CG 1 ATOM 7481 C CD1 . PHE B 1 421 ? -46.511 -23.817 46.689 1.00 69.02 ? 421 PHE B CD1 1 ATOM 7482 C CD2 . PHE B 1 421 ? -46.552 -26.162 46.220 1.00 70.41 ? 421 PHE B CD2 1 ATOM 7483 C CE1 . PHE B 1 421 ? -45.227 -23.920 47.176 1.00 70.31 ? 421 PHE B CE1 1 ATOM 7484 C CE2 . PHE B 1 421 ? -45.259 -26.278 46.703 1.00 71.66 ? 421 PHE B CE2 1 ATOM 7485 C CZ . PHE B 1 421 ? -44.596 -25.151 47.188 1.00 71.49 ? 421 PHE B CZ 1 ATOM 7486 N N . GLU B 1 422 ? -46.991 -25.148 42.600 1.00 67.11 ? 422 GLU B N 1 ATOM 7487 C CA . GLU B 1 422 ? -46.409 -26.119 41.690 1.00 68.42 ? 422 GLU B CA 1 ATOM 7488 C C . GLU B 1 422 ? -44.893 -26.193 41.745 1.00 69.07 ? 422 GLU B C 1 ATOM 7489 O O . GLU B 1 422 ? -44.228 -26.289 40.708 1.00 68.87 ? 422 GLU B O 1 ATOM 7490 C CB . GLU B 1 422 ? -46.864 -25.847 40.260 1.00 68.59 ? 422 GLU B CB 1 ATOM 7491 C CG . GLU B 1 422 ? -46.490 -24.471 39.745 1.00 69.81 ? 422 GLU B CG 1 ATOM 7492 C CD . GLU B 1 422 ? -47.236 -24.119 38.478 1.00 71.38 ? 422 GLU B CD 1 ATOM 7493 O OE1 . GLU B 1 422 ? -48.147 -24.886 38.092 1.00 71.37 ? 422 GLU B OE1 1 ATOM 7494 O OE2 . GLU B 1 422 ? -46.918 -23.070 37.870 1.00 73.66 ? 422 GLU B OE2 1 ATOM 7495 N N . HIS B 1 423 ? -44.335 -26.163 42.948 1.00 70.03 ? 423 HIS B N 1 ATOM 7496 C CA . HIS B 1 423 ? -42.895 -26.322 43.048 1.00 70.88 ? 423 HIS B CA 1 ATOM 7497 C C . HIS B 1 423 ? -42.473 -27.540 43.859 1.00 71.39 ? 423 HIS B C 1 ATOM 7498 O O . HIS B 1 423 ? -42.986 -27.788 44.957 1.00 71.16 ? 423 HIS B O 1 ATOM 7499 C CB . HIS B 1 423 ? -42.249 -25.082 43.622 1.00 70.93 ? 423 HIS B CB 1 ATOM 7500 C CG . HIS B 1 423 ? -40.774 -25.220 43.770 1.00 72.07 ? 423 HIS B CG 1 ATOM 7501 N ND1 . HIS B 1 423 ? -39.906 -25.041 42.712 1.00 73.19 ? 423 HIS B ND1 1 ATOM 7502 C CD2 . HIS B 1 423 ? -40.010 -25.554 44.839 1.00 72.36 ? 423 HIS B CD2 1 ATOM 7503 C CE1 . HIS B 1 423 ? -38.666 -25.237 43.129 1.00 73.50 ? 423 HIS B CE1 1 ATOM 7504 N NE2 . HIS B 1 423 ? -38.703 -25.552 44.415 1.00 73.55 ? 423 HIS B NE2 1 ATOM 7505 N N . ARG B 1 424 ? -41.521 -28.288 43.314 1.00 72.15 ? 424 ARG B N 1 ATOM 7506 C CA . ARG B 1 424 ? -41.022 -29.480 43.986 1.00 73.07 ? 424 ARG B CA 1 ATOM 7507 C C . ARG B 1 424 ? -39.768 -29.151 44.785 1.00 73.33 ? 424 ARG B C 1 ATOM 7508 O O . ARG B 1 424 ? -38.718 -28.867 44.200 1.00 73.67 ? 424 ARG B O 1 ATOM 7509 C CB . ARG B 1 424 ? -40.702 -30.570 42.964 1.00 73.32 ? 424 ARG B CB 1 ATOM 7510 C CG . ARG B 1 424 ? -40.160 -31.869 43.574 1.00 75.07 ? 424 ARG B CG 1 ATOM 7511 C CD . ARG B 1 424 ? -39.952 -32.918 42.486 1.00 78.15 ? 424 ARG B CD 1 ATOM 7512 N NE . ARG B 1 424 ? -39.157 -34.071 42.909 1.00 79.49 ? 424 ARG B NE 1 ATOM 7513 C CZ . ARG B 1 424 ? -39.645 -35.094 43.605 1.00 79.90 ? 424 ARG B CZ 1 ATOM 7514 N NH1 . ARG B 1 424 ? -40.917 -35.092 43.978 1.00 80.03 ? 424 ARG B NH1 1 ATOM 7515 N NH2 . ARG B 1 424 ? -38.860 -36.112 43.936 1.00 80.08 ? 424 ARG B NH2 1 ATOM 7516 N N . SER B 1 425 ? -39.873 -29.178 46.113 1.00 73.46 ? 425 SER B N 1 ATOM 7517 C CA . SER B 1 425 ? -38.714 -28.958 46.970 1.00 73.49 ? 425 SER B CA 1 ATOM 7518 C C . SER B 1 425 ? -37.569 -29.818 46.441 1.00 73.58 ? 425 SER B C 1 ATOM 7519 O O . SER B 1 425 ? -37.762 -30.997 46.133 1.00 73.71 ? 425 SER B O 1 ATOM 7520 C CB . SER B 1 425 ? -39.067 -29.323 48.415 1.00 73.63 ? 425 SER B CB 1 ATOM 7521 O OG . SER B 1 425 ? -37.957 -29.837 49.137 1.00 74.40 ? 425 SER B OG 1 ATOM 7522 N N . SER B 1 426 ? -36.383 -29.238 46.307 1.00 73.70 ? 426 SER B N 1 ATOM 7523 C CA . SER B 1 426 ? -35.234 -29.998 45.812 1.00 73.94 ? 426 SER B CA 1 ATOM 7524 C C . SER B 1 426 ? -34.640 -30.916 46.884 1.00 74.02 ? 426 SER B C 1 ATOM 7525 O O . SER B 1 426 ? -33.756 -31.718 46.610 1.00 74.00 ? 426 SER B O 1 ATOM 7526 C CB . SER B 1 426 ? -34.165 -29.058 45.262 1.00 74.10 ? 426 SER B CB 1 ATOM 7527 O OG . SER B 1 426 ? -33.985 -27.933 46.110 1.00 74.89 ? 426 SER B OG 1 ATOM 7528 N N . LYS B 1 427 ? -35.130 -30.776 48.112 1.00 74.18 ? 427 LYS B N 1 ATOM 7529 C CA . LYS B 1 427 ? -34.763 -31.657 49.213 1.00 74.25 ? 427 LYS B CA 1 ATOM 7530 C C . LYS B 1 427 ? -35.854 -32.707 49.432 1.00 73.94 ? 427 LYS B C 1 ATOM 7531 O O . LYS B 1 427 ? -36.030 -33.200 50.552 1.00 74.43 ? 427 LYS B O 1 ATOM 7532 C CB . LYS B 1 427 ? -34.634 -30.838 50.490 1.00 74.51 ? 427 LYS B CB 1 ATOM 7533 C CG . LYS B 1 427 ? -33.261 -30.248 50.758 1.00 76.56 ? 427 LYS B CG 1 ATOM 7534 C CD . LYS B 1 427 ? -33.317 -29.185 51.895 1.00 79.98 ? 427 LYS B CD 1 ATOM 7535 C CE . LYS B 1 427 ? -34.380 -29.514 52.976 1.00 81.03 ? 427 LYS B CE 1 ATOM 7536 N NZ . LYS B 1 427 ? -33.856 -30.284 54.139 1.00 81.69 ? 427 LYS B NZ 1 ATOM 7537 N N . LEU B 1 428 ? -36.604 -33.029 48.376 1.00 73.14 ? 428 LEU B N 1 ATOM 7538 C CA . LEU B 1 428 ? -37.780 -33.904 48.509 1.00 72.06 ? 428 LEU B CA 1 ATOM 7539 C C . LEU B 1 428 ? -37.333 -35.379 48.502 1.00 71.07 ? 428 LEU B C 1 ATOM 7540 O O . LEU B 1 428 ? -36.770 -35.877 47.520 1.00 70.88 ? 428 LEU B O 1 ATOM 7541 C CB . LEU B 1 428 ? -38.834 -33.592 47.410 1.00 72.14 ? 428 LEU B CB 1 ATOM 7542 C CG . LEU B 1 428 ? -40.357 -33.860 47.583 1.00 72.21 ? 428 LEU B CG 1 ATOM 7543 C CD1 . LEU B 1 428 ? -40.745 -35.299 47.169 1.00 72.43 ? 428 LEU B CD1 1 ATOM 7544 C CD2 . LEU B 1 428 ? -40.951 -33.474 48.998 1.00 70.92 ? 428 LEU B CD2 1 ATOM 7545 N N . PRO B 1 429 ? -37.560 -36.072 49.620 1.00 70.08 ? 429 PRO B N 1 ATOM 7546 C CA . PRO B 1 429 ? -37.075 -37.438 49.769 1.00 69.46 ? 429 PRO B CA 1 ATOM 7547 C C . PRO B 1 429 ? -37.728 -38.460 48.828 1.00 68.94 ? 429 PRO B C 1 ATOM 7548 O O . PRO B 1 429 ? -37.110 -39.497 48.543 1.00 68.98 ? 429 PRO B O 1 ATOM 7549 C CB . PRO B 1 429 ? -37.396 -37.775 51.234 1.00 69.58 ? 429 PRO B CB 1 ATOM 7550 C CG . PRO B 1 429 ? -38.436 -36.790 51.656 1.00 69.99 ? 429 PRO B CG 1 ATOM 7551 C CD . PRO B 1 429 ? -38.190 -35.552 50.848 1.00 70.10 ? 429 PRO B CD 1 ATOM 7552 N N . TRP B 1 430 ? -38.957 -38.191 48.361 1.00 68.13 ? 430 TRP B N 1 ATOM 7553 C CA . TRP B 1 430 ? -39.647 -39.093 47.416 1.00 66.91 ? 430 TRP B CA 1 ATOM 7554 C C . TRP B 1 430 ? -39.101 -38.890 46.011 1.00 67.05 ? 430 TRP B C 1 ATOM 7555 O O . TRP B 1 430 ? -38.412 -37.900 45.730 1.00 66.88 ? 430 TRP B O 1 ATOM 7556 C CB . TRP B 1 430 ? -41.156 -38.865 47.409 1.00 66.40 ? 430 TRP B CB 1 ATOM 7557 C CG . TRP B 1 430 ? -41.797 -38.797 48.781 1.00 64.93 ? 430 TRP B CG 1 ATOM 7558 C CD1 . TRP B 1 430 ? -41.892 -37.696 49.603 1.00 62.76 ? 430 TRP B CD1 1 ATOM 7559 C CD2 . TRP B 1 430 ? -42.443 -39.867 49.481 1.00 62.68 ? 430 TRP B CD2 1 ATOM 7560 N NE1 . TRP B 1 430 ? -42.550 -38.024 50.758 1.00 61.53 ? 430 TRP B NE1 1 ATOM 7561 C CE2 . TRP B 1 430 ? -42.902 -39.347 50.714 1.00 61.46 ? 430 TRP B CE2 1 ATOM 7562 C CE3 . TRP B 1 430 ? -42.670 -41.216 49.189 1.00 62.34 ? 430 TRP B CE3 1 ATOM 7563 C CZ2 . TRP B 1 430 ? -43.581 -40.124 51.651 1.00 61.03 ? 430 TRP B CZ2 1 ATOM 7564 C CZ3 . TRP B 1 430 ? -43.342 -41.995 50.135 1.00 61.74 ? 430 TRP B CZ3 1 ATOM 7565 C CH2 . TRP B 1 430 ? -43.793 -41.439 51.347 1.00 60.82 ? 430 TRP B CH2 1 ATOM 7566 N N . PRO B 1 431 ? -39.407 -39.834 45.113 1.00 67.19 ? 431 PRO B N 1 ATOM 7567 C CA . PRO B 1 431 ? -38.904 -39.845 43.725 1.00 67.23 ? 431 PRO B CA 1 ATOM 7568 C C . PRO B 1 431 ? -39.491 -38.740 42.841 1.00 67.45 ? 431 PRO B C 1 ATOM 7569 O O . PRO B 1 431 ? -40.546 -38.173 43.153 1.00 67.62 ? 431 PRO B O 1 ATOM 7570 C CB . PRO B 1 431 ? -39.311 -41.224 43.203 1.00 66.83 ? 431 PRO B CB 1 ATOM 7571 C CG . PRO B 1 431 ? -40.419 -41.677 44.082 1.00 66.90 ? 431 PRO B CG 1 ATOM 7572 C CD . PRO B 1 431 ? -40.258 -40.997 45.422 1.00 67.19 ? 431 PRO B CD 1 ATOM 7573 N N . GLU B 1 432 ? -38.794 -38.447 41.748 1.00 67.61 ? 432 GLU B N 1 ATOM 7574 C CA . GLU B 1 432 ? -39.219 -37.422 40.801 1.00 67.82 ? 432 GLU B CA 1 ATOM 7575 C C . GLU B 1 432 ? -40.696 -37.584 40.409 1.00 67.84 ? 432 GLU B C 1 ATOM 7576 O O . GLU B 1 432 ? -41.465 -36.619 40.431 1.00 68.27 ? 432 GLU B O 1 ATOM 7577 C CB . GLU B 1 432 ? -38.345 -37.467 39.543 1.00 67.92 ? 432 GLU B CB 1 ATOM 7578 C CG . GLU B 1 432 ? -36.841 -37.539 39.798 0.50 68.17 ? 432 GLU B CG 1 ATOM 7579 C CD . GLU B 1 432 ? -36.162 -36.189 39.670 0.50 68.68 ? 432 GLU B CD 1 ATOM 7580 O OE1 . GLU B 1 432 ? -35.484 -35.741 40.621 0.50 68.33 ? 432 GLU B OE1 1 ATOM 7581 O OE2 . GLU B 1 432 ? -36.312 -35.565 38.604 0.50 69.22 ? 432 GLU B OE2 1 ATOM 7582 N N . TRP B 1 433 ? -41.108 -38.800 40.068 1.00 67.40 ? 433 TRP B N 1 ATOM 7583 C CA . TRP B 1 433 ? -42.439 -38.964 39.505 1.00 67.10 ? 433 TRP B CA 1 ATOM 7584 C C . TRP B 1 433 ? -43.583 -38.524 40.432 1.00 66.71 ? 433 TRP B C 1 ATOM 7585 O O . TRP B 1 433 ? -44.644 -38.146 39.968 1.00 67.20 ? 433 TRP B O 1 ATOM 7586 C CB . TRP B 1 433 ? -42.661 -40.384 38.982 1.00 67.05 ? 433 TRP B CB 1 ATOM 7587 C CG . TRP B 1 433 ? -42.812 -41.412 40.033 1.00 67.47 ? 433 TRP B CG 1 ATOM 7588 C CD1 . TRP B 1 433 ? -41.855 -42.290 40.460 1.00 68.21 ? 433 TRP B CD1 1 ATOM 7589 C CD2 . TRP B 1 433 ? -43.997 -41.709 40.787 1.00 67.95 ? 433 TRP B CD2 1 ATOM 7590 N NE1 . TRP B 1 433 ? -42.372 -43.123 41.435 1.00 69.00 ? 433 TRP B NE1 1 ATOM 7591 C CE2 . TRP B 1 433 ? -43.682 -42.783 41.658 1.00 68.72 ? 433 TRP B CE2 1 ATOM 7592 C CE3 . TRP B 1 433 ? -45.291 -41.181 40.807 1.00 67.46 ? 433 TRP B CE3 1 ATOM 7593 C CZ2 . TRP B 1 433 ? -44.607 -43.326 42.544 1.00 68.65 ? 433 TRP B CZ2 1 ATOM 7594 C CZ3 . TRP B 1 433 ? -46.215 -41.723 41.694 1.00 68.72 ? 433 TRP B CZ3 1 ATOM 7595 C CH2 . TRP B 1 433 ? -45.863 -42.782 42.554 1.00 68.65 ? 433 TRP B CH2 1 ATOM 7596 N N . MET B 1 434 ? -43.396 -38.557 41.738 1.00 65.89 ? 434 MET B N 1 ATOM 7597 C CA . MET B 1 434 ? -44.495 -38.114 42.588 1.00 64.85 ? 434 MET B CA 1 ATOM 7598 C C . MET B 1 434 ? -44.740 -36.610 42.499 1.00 63.90 ? 434 MET B C 1 ATOM 7599 O O . MET B 1 434 ? -45.726 -36.113 43.038 1.00 63.58 ? 434 MET B O 1 ATOM 7600 C CB . MET B 1 434 ? -44.292 -38.587 44.026 1.00 65.07 ? 434 MET B CB 1 ATOM 7601 C CG . MET B 1 434 ? -44.547 -40.062 44.127 1.00 65.64 ? 434 MET B CG 1 ATOM 7602 S SD . MET B 1 434 ? -44.006 -40.809 45.656 1.00 69.99 ? 434 MET B SD 1 ATOM 7603 C CE . MET B 1 434 ? -45.385 -40.584 46.788 1.00 68.01 ? 434 MET B CE 1 ATOM 7604 N N . GLY B 1 435 ? -43.845 -35.903 41.805 1.00 62.99 ? 435 GLY B N 1 ATOM 7605 C CA . GLY B 1 435 ? -43.941 -34.442 41.604 1.00 62.01 ? 435 GLY B CA 1 ATOM 7606 C C . GLY B 1 435 ? -44.271 -33.564 42.821 1.00 61.38 ? 435 GLY B C 1 ATOM 7607 O O . GLY B 1 435 ? -43.973 -33.905 43.974 1.00 61.56 ? 435 GLY B O 1 ATOM 7608 N N . VAL B 1 436 ? -44.889 -32.417 42.566 1.00 60.10 ? 436 VAL B N 1 ATOM 7609 C CA . VAL B 1 436 ? -45.294 -31.522 43.646 1.00 58.82 ? 436 VAL B CA 1 ATOM 7610 C C . VAL B 1 436 ? -46.315 -32.172 44.593 1.00 58.17 ? 436 VAL B C 1 ATOM 7611 O O . VAL B 1 436 ? -47.518 -32.018 44.416 1.00 57.85 ? 436 VAL B O 1 ATOM 7612 C CB . VAL B 1 436 ? -45.852 -30.216 43.048 1.00 58.83 ? 436 VAL B CB 1 ATOM 7613 C CG1 . VAL B 1 436 ? -46.191 -29.181 44.141 1.00 58.74 ? 436 VAL B CG1 1 ATOM 7614 C CG2 . VAL B 1 436 ? -44.860 -29.652 42.018 1.00 58.06 ? 436 VAL B CG2 1 ATOM 7615 N N . MET B 1 437 ? -45.830 -32.880 45.608 1.00 57.66 ? 437 MET B N 1 ATOM 7616 C CA . MET B 1 437 ? -46.703 -33.752 46.430 1.00 57.53 ? 437 MET B CA 1 ATOM 7617 C C . MET B 1 437 ? -47.644 -33.113 47.463 1.00 57.17 ? 437 MET B C 1 ATOM 7618 O O . MET B 1 437 ? -47.485 -31.953 47.872 1.00 56.49 ? 437 MET B O 1 ATOM 7619 C CB . MET B 1 437 ? -45.886 -34.829 47.144 1.00 57.54 ? 437 MET B CB 1 ATOM 7620 C CG . MET B 1 437 ? -45.423 -35.968 46.248 1.00 58.84 ? 437 MET B CG 1 ATOM 7621 S SD . MET B 1 437 ? -44.274 -37.094 47.091 1.00 60.15 ? 437 MET B SD 1 ATOM 7622 C CE . MET B 1 437 ? -45.166 -37.336 48.641 1.00 60.93 ? 437 MET B CE 1 ATOM 7623 N N . HIS B 1 438 ? -48.623 -33.911 47.885 1.00 57.11 ? 438 HIS B N 1 ATOM 7624 C CA . HIS B 1 438 ? -49.597 -33.469 48.849 1.00 57.38 ? 438 HIS B CA 1 ATOM 7625 C C . HIS B 1 438 ? -48.829 -33.039 50.070 1.00 57.86 ? 438 HIS B C 1 ATOM 7626 O O . HIS B 1 438 ? -47.873 -33.712 50.444 1.00 58.17 ? 438 HIS B O 1 ATOM 7627 C CB . HIS B 1 438 ? -50.520 -34.620 49.218 1.00 56.99 ? 438 HIS B CB 1 ATOM 7628 C CG . HIS B 1 438 ? -51.483 -34.298 50.327 1.00 57.18 ? 438 HIS B CG 1 ATOM 7629 N ND1 . HIS B 1 438 ? -52.245 -33.148 50.352 1.00 56.85 ? 438 HIS B ND1 1 ATOM 7630 C CD2 . HIS B 1 438 ? -51.835 -34.998 51.437 1.00 57.24 ? 438 HIS B CD2 1 ATOM 7631 C CE1 . HIS B 1 438 ? -53.008 -33.147 51.435 1.00 56.64 ? 438 HIS B CE1 1 ATOM 7632 N NE2 . HIS B 1 438 ? -52.781 -34.257 52.111 1.00 56.35 ? 438 HIS B NE2 1 ATOM 7633 N N . GLY B 1 439 ? -49.220 -31.930 50.694 1.00 58.00 ? 439 GLY B N 1 ATOM 7634 C CA . GLY B 1 439 ? -48.565 -31.517 51.940 1.00 58.10 ? 439 GLY B CA 1 ATOM 7635 C C . GLY B 1 439 ? -47.118 -31.030 51.858 1.00 58.45 ? 439 GLY B C 1 ATOM 7636 O O . GLY B 1 439 ? -46.483 -30.787 52.886 1.00 57.96 ? 439 GLY B O 1 ATOM 7637 N N . TYR B 1 440 ? -46.586 -30.864 50.647 1.00 59.02 ? 440 TYR B N 1 ATOM 7638 C CA . TYR B 1 440 ? -45.200 -30.409 50.518 1.00 59.56 ? 440 TYR B CA 1 ATOM 7639 C C . TYR B 1 440 ? -45.052 -28.948 50.142 1.00 59.69 ? 440 TYR B C 1 ATOM 7640 O O . TYR B 1 440 ? -44.059 -28.537 49.540 1.00 59.75 ? 440 TYR B O 1 ATOM 7641 C CB . TYR B 1 440 ? -44.354 -31.348 49.651 1.00 59.79 ? 440 TYR B CB 1 ATOM 7642 C CG . TYR B 1 440 ? -43.938 -32.554 50.463 1.00 61.61 ? 440 TYR B CG 1 ATOM 7643 C CD1 . TYR B 1 440 ? -44.584 -33.789 50.308 1.00 62.74 ? 440 TYR B CD1 1 ATOM 7644 C CD2 . TYR B 1 440 ? -42.956 -32.438 51.457 1.00 62.90 ? 440 TYR B CD2 1 ATOM 7645 C CE1 . TYR B 1 440 ? -44.225 -34.893 51.096 1.00 63.70 ? 440 TYR B CE1 1 ATOM 7646 C CE2 . TYR B 1 440 ? -42.587 -33.522 52.244 1.00 63.33 ? 440 TYR B CE2 1 ATOM 7647 C CZ . TYR B 1 440 ? -43.225 -34.745 52.065 1.00 63.92 ? 440 TYR B CZ 1 ATOM 7648 O OH . TYR B 1 440 ? -42.859 -35.817 52.847 1.00 64.26 ? 440 TYR B OH 1 ATOM 7649 N N . GLU B 1 441 ? -46.037 -28.162 50.548 1.00 59.83 ? 441 GLU B N 1 ATOM 7650 C CA . GLU B 1 441 ? -45.942 -26.724 50.436 1.00 60.22 ? 441 GLU B CA 1 ATOM 7651 C C . GLU B 1 441 ? -45.836 -26.162 51.853 1.00 60.12 ? 441 GLU B C 1 ATOM 7652 O O . GLU B 1 441 ? -45.351 -25.042 52.053 1.00 59.83 ? 441 GLU B O 1 ATOM 7653 C CB . GLU B 1 441 ? -47.173 -26.161 49.720 1.00 60.40 ? 441 GLU B CB 1 ATOM 7654 C CG . GLU B 1 441 ? -48.353 -25.788 50.634 1.00 62.15 ? 441 GLU B CG 1 ATOM 7655 C CD . GLU B 1 441 ? -49.101 -27.005 51.200 1.00 65.14 ? 441 GLU B CD 1 ATOM 7656 O OE1 . GLU B 1 441 ? -48.870 -28.142 50.698 1.00 66.23 ? 441 GLU B OE1 1 ATOM 7657 O OE2 . GLU B 1 441 ? -49.929 -26.830 52.143 1.00 65.16 ? 441 GLU B OE2 1 ATOM 7658 N N . ILE B 1 442 ? -46.281 -26.950 52.835 1.00 59.94 ? 442 ILE B N 1 ATOM 7659 C CA . ILE B 1 442 ? -46.317 -26.498 54.224 1.00 60.02 ? 442 ILE B CA 1 ATOM 7660 C C . ILE B 1 442 ? -44.987 -25.889 54.655 1.00 60.51 ? 442 ILE B C 1 ATOM 7661 O O . ILE B 1 442 ? -44.951 -24.812 55.242 1.00 60.55 ? 442 ILE B O 1 ATOM 7662 C CB . ILE B 1 442 ? -46.656 -27.645 55.181 1.00 59.93 ? 442 ILE B CB 1 ATOM 7663 C CG1 . ILE B 1 442 ? -48.020 -28.251 54.811 1.00 59.51 ? 442 ILE B CG1 1 ATOM 7664 C CG2 . ILE B 1 442 ? -46.623 -27.157 56.625 1.00 59.51 ? 442 ILE B CG2 1 ATOM 7665 C CD1 . ILE B 1 442 ? -48.489 -29.399 55.739 1.00 58.31 ? 442 ILE B CD1 1 ATOM 7666 N N . GLU B 1 443 ? -43.891 -26.585 54.360 1.00 61.19 ? 443 GLU B N 1 ATOM 7667 C CA . GLU B 1 443 ? -42.551 -26.088 54.698 1.00 61.43 ? 443 GLU B CA 1 ATOM 7668 C C . GLU B 1 443 ? -42.300 -24.681 54.124 1.00 61.18 ? 443 GLU B C 1 ATOM 7669 O O . GLU B 1 443 ? -41.721 -23.843 54.800 1.00 61.34 ? 443 GLU B O 1 ATOM 7670 C CB . GLU B 1 443 ? -41.439 -27.095 54.300 1.00 61.53 ? 443 GLU B CB 1 ATOM 7671 C CG . GLU B 1 443 ? -41.288 -27.395 52.788 1.00 63.52 ? 443 GLU B CG 1 ATOM 7672 C CD . GLU B 1 443 ? -40.496 -28.711 52.510 1.00 66.63 ? 443 GLU B CD 1 ATOM 7673 O OE1 . GLU B 1 443 ? -40.887 -29.780 53.051 1.00 68.73 ? 443 GLU B OE1 1 ATOM 7674 O OE2 . GLU B 1 443 ? -39.488 -28.689 51.754 1.00 65.94 ? 443 GLU B OE2 1 ATOM 7675 N N . PHE B 1 444 ? -42.754 -24.409 52.901 1.00 60.96 ? 444 PHE B N 1 ATOM 7676 C CA . PHE B 1 444 ? -42.526 -23.101 52.297 1.00 60.52 ? 444 PHE B CA 1 ATOM 7677 C C . PHE B 1 444 ? -43.429 -22.087 52.905 1.00 60.57 ? 444 PHE B C 1 ATOM 7678 O O . PHE B 1 444 ? -43.123 -20.908 52.921 1.00 60.78 ? 444 PHE B O 1 ATOM 7679 C CB . PHE B 1 444 ? -42.828 -23.121 50.829 1.00 60.45 ? 444 PHE B CB 1 ATOM 7680 C CG . PHE B 1 444 ? -41.764 -23.727 50.006 1.00 60.80 ? 444 PHE B CG 1 ATOM 7681 C CD1 . PHE B 1 444 ? -41.511 -25.083 50.064 1.00 61.35 ? 444 PHE B CD1 1 ATOM 7682 C CD2 . PHE B 1 444 ? -41.032 -22.942 49.144 1.00 61.47 ? 444 PHE B CD2 1 ATOM 7683 C CE1 . PHE B 1 444 ? -40.531 -25.644 49.275 1.00 62.34 ? 444 PHE B CE1 1 ATOM 7684 C CE2 . PHE B 1 444 ? -40.040 -23.486 48.347 1.00 61.63 ? 444 PHE B CE2 1 ATOM 7685 C CZ . PHE B 1 444 ? -39.787 -24.841 48.408 1.00 62.35 ? 444 PHE B CZ 1 ATOM 7686 N N . VAL B 1 445 ? -44.567 -22.528 53.396 1.00 60.77 ? 445 VAL B N 1 ATOM 7687 C CA . VAL B 1 445 ? -45.419 -21.596 54.110 1.00 61.08 ? 445 VAL B CA 1 ATOM 7688 C C . VAL B 1 445 ? -44.788 -21.212 55.446 1.00 61.57 ? 445 VAL B C 1 ATOM 7689 O O . VAL B 1 445 ? -44.738 -20.037 55.774 1.00 61.88 ? 445 VAL B O 1 ATOM 7690 C CB . VAL B 1 445 ? -46.834 -22.137 54.348 1.00 60.87 ? 445 VAL B CB 1 ATOM 7691 C CG1 . VAL B 1 445 ? -47.656 -21.128 55.111 1.00 60.43 ? 445 VAL B CG1 1 ATOM 7692 C CG2 . VAL B 1 445 ? -47.499 -22.451 53.032 1.00 61.24 ? 445 VAL B CG2 1 ATOM 7693 N N . PHE B 1 446 ? -44.287 -22.180 56.211 1.00 62.09 ? 446 PHE B N 1 ATOM 7694 C CA . PHE B 1 446 ? -43.699 -21.859 57.523 1.00 62.69 ? 446 PHE B CA 1 ATOM 7695 C C . PHE B 1 446 ? -42.287 -21.302 57.386 1.00 63.74 ? 446 PHE B C 1 ATOM 7696 O O . PHE B 1 446 ? -41.595 -21.022 58.382 1.00 63.26 ? 446 PHE B O 1 ATOM 7697 C CB . PHE B 1 446 ? -43.715 -23.063 58.457 1.00 62.24 ? 446 PHE B CB 1 ATOM 7698 C CG . PHE B 1 446 ? -45.056 -23.340 59.069 1.00 60.97 ? 446 PHE B CG 1 ATOM 7699 C CD1 . PHE B 1 446 ? -45.997 -24.078 58.387 1.00 60.10 ? 446 PHE B CD1 1 ATOM 7700 C CD2 . PHE B 1 446 ? -45.366 -22.869 60.331 1.00 60.18 ? 446 PHE B CD2 1 ATOM 7701 C CE1 . PHE B 1 446 ? -47.233 -24.348 58.957 1.00 60.99 ? 446 PHE B CE1 1 ATOM 7702 C CE2 . PHE B 1 446 ? -46.604 -23.131 60.913 1.00 60.16 ? 446 PHE B CE2 1 ATOM 7703 C CZ . PHE B 1 446 ? -47.542 -23.869 60.230 1.00 60.11 ? 446 PHE B CZ 1 ATOM 7704 N N . GLY B 1 447 ? -41.878 -21.142 56.127 1.00 65.18 ? 447 GLY B N 1 ATOM 7705 C CA . GLY B 1 447 ? -40.657 -20.430 55.778 1.00 66.99 ? 447 GLY B CA 1 ATOM 7706 C C . GLY B 1 447 ? -39.377 -21.182 56.071 1.00 68.29 ? 447 GLY B C 1 ATOM 7707 O O . GLY B 1 447 ? -38.329 -20.569 56.253 1.00 68.73 ? 447 GLY B O 1 ATOM 7708 N N . LEU B 1 448 ? -39.447 -22.507 56.108 1.00 69.44 ? 448 LEU B N 1 ATOM 7709 C CA . LEU B 1 448 ? -38.255 -23.288 56.389 1.00 70.93 ? 448 LEU B CA 1 ATOM 7710 C C . LEU B 1 448 ? -37.083 -22.987 55.439 1.00 72.47 ? 448 LEU B C 1 ATOM 7711 O O . LEU B 1 448 ? -35.919 -23.018 55.850 1.00 72.90 ? 448 LEU B O 1 ATOM 7712 C CB . LEU B 1 448 ? -38.568 -24.780 56.409 1.00 70.52 ? 448 LEU B CB 1 ATOM 7713 C CG . LEU B 1 448 ? -39.055 -25.193 57.800 1.00 69.73 ? 448 LEU B CG 1 ATOM 7714 C CD1 . LEU B 1 448 ? -40.346 -24.433 58.171 1.00 68.76 ? 448 LEU B CD1 1 ATOM 7715 C CD2 . LEU B 1 448 ? -39.228 -26.711 57.914 1.00 68.54 ? 448 LEU B CD2 1 ATOM 7716 N N . PRO B 1 449 ? -37.378 -22.700 54.164 1.00 73.59 ? 449 PRO B N 1 ATOM 7717 C CA . PRO B 1 449 ? -36.258 -22.417 53.283 1.00 74.48 ? 449 PRO B CA 1 ATOM 7718 C C . PRO B 1 449 ? -35.582 -21.090 53.604 1.00 75.72 ? 449 PRO B C 1 ATOM 7719 O O . PRO B 1 449 ? -34.653 -20.695 52.899 1.00 75.99 ? 449 PRO B O 1 ATOM 7720 C CB . PRO B 1 449 ? -36.909 -22.359 51.889 1.00 74.43 ? 449 PRO B CB 1 ATOM 7721 C CG . PRO B 1 449 ? -38.197 -23.099 52.028 1.00 73.77 ? 449 PRO B CG 1 ATOM 7722 C CD . PRO B 1 449 ? -38.649 -22.852 53.432 1.00 73.52 ? 449 PRO B CD 1 ATOM 7723 N N . LEU B 1 450 ? -36.043 -20.389 54.630 1.00 77.27 ? 450 LEU B N 1 ATOM 7724 C CA . LEU B 1 450 ? -35.460 -19.087 54.947 1.00 79.36 ? 450 LEU B CA 1 ATOM 7725 C C . LEU B 1 450 ? -34.165 -19.289 55.724 1.00 81.52 ? 450 LEU B C 1 ATOM 7726 O O . LEU B 1 450 ? -33.299 -18.420 55.796 1.00 81.72 ? 450 LEU B O 1 ATOM 7727 C CB . LEU B 1 450 ? -36.451 -18.245 55.745 1.00 78.76 ? 450 LEU B CB 1 ATOM 7728 C CG . LEU B 1 450 ? -37.630 -17.712 54.944 1.00 77.33 ? 450 LEU B CG 1 ATOM 7729 C CD1 . LEU B 1 450 ? -38.550 -16.935 55.836 1.00 75.62 ? 450 LEU B CD1 1 ATOM 7730 C CD2 . LEU B 1 450 ? -37.122 -16.846 53.804 1.00 76.67 ? 450 LEU B CD2 1 ATOM 7731 N N . GLU B 1 451 ? -34.063 -20.470 56.304 1.00 84.34 ? 451 GLU B N 1 ATOM 7732 C CA . GLU B 1 451 ? -32.899 -20.915 57.016 1.00 87.32 ? 451 GLU B CA 1 ATOM 7733 C C . GLU B 1 451 ? -31.741 -21.173 56.051 1.00 88.88 ? 451 GLU B C 1 ATOM 7734 O O . GLU B 1 451 ? -31.783 -22.114 55.256 1.00 88.66 ? 451 GLU B O 1 ATOM 7735 C CB . GLU B 1 451 ? -33.271 -22.210 57.723 1.00 87.60 ? 451 GLU B CB 1 ATOM 7736 C CG . GLU B 1 451 ? -32.197 -22.792 58.575 1.00 90.69 ? 451 GLU B CG 1 ATOM 7737 C CD . GLU B 1 451 ? -32.204 -22.167 59.955 1.00 95.38 ? 451 GLU B CD 1 ATOM 7738 O OE1 . GLU B 1 451 ? -32.838 -22.752 60.879 1.00 96.79 ? 451 GLU B OE1 1 ATOM 7739 O OE2 . GLU B 1 451 ? -31.610 -21.065 60.094 1.00 97.26 ? 451 GLU B OE2 1 ATOM 7740 N N . ARG B 1 452 ? -30.705 -20.335 56.135 1.00 91.41 ? 452 ARG B N 1 ATOM 7741 C CA . ARG B 1 452 ? -29.563 -20.356 55.193 1.00 93.68 ? 452 ARG B CA 1 ATOM 7742 C C . ARG B 1 452 ? -28.829 -21.705 55.135 1.00 94.48 ? 452 ARG B C 1 ATOM 7743 O O . ARG B 1 452 ? -28.885 -22.408 54.116 1.00 94.72 ? 452 ARG B O 1 ATOM 7744 C CB . ARG B 1 452 ? -28.573 -19.206 55.487 1.00 94.17 ? 452 ARG B CB 1 ATOM 7745 C CG . ARG B 1 452 ? -29.102 -17.783 55.158 1.00 96.86 ? 452 ARG B CG 1 ATOM 7746 C CD . ARG B 1 452 ? -29.399 -17.576 53.654 1.00 101.43 ? 452 ARG B CD 1 ATOM 7747 N NE . ARG B 1 452 ? -30.127 -18.715 53.068 1.00 105.07 ? 452 ARG B NE 1 ATOM 7748 C CZ . ARG B 1 452 ? -30.458 -18.840 51.779 1.00 106.72 ? 452 ARG B CZ 1 ATOM 7749 N NH1 . ARG B 1 452 ? -30.151 -17.884 50.902 1.00 107.76 ? 452 ARG B NH1 1 ATOM 7750 N NH2 . ARG B 1 452 ? -31.109 -19.923 51.364 1.00 107.14 ? 452 ARG B NH2 1 ATOM 7751 N N . ARG B 1 453 ? -28.142 -22.051 56.227 1.00 95.48 ? 453 ARG B N 1 ATOM 7752 C CA . ARG B 1 453 ? -27.577 -23.396 56.416 1.00 96.23 ? 453 ARG B CA 1 ATOM 7753 C C . ARG B 1 453 ? -28.702 -24.456 56.398 1.00 95.74 ? 453 ARG B C 1 ATOM 7754 O O . ARG B 1 453 ? -29.039 -25.026 57.445 1.00 95.63 ? 453 ARG B O 1 ATOM 7755 C CB . ARG B 1 453 ? -26.842 -23.474 57.769 1.00 96.98 ? 453 ARG B CB 1 ATOM 7756 C CG . ARG B 1 453 ? -25.838 -22.341 58.051 1.00 99.30 ? 453 ARG B CG 1 ATOM 7757 C CD . ARG B 1 453 ? -24.433 -22.734 57.583 1.00 103.04 ? 453 ARG B CD 1 ATOM 7758 N NE . ARG B 1 453 ? -23.415 -21.754 57.976 1.00 104.83 ? 453 ARG B NE 1 ATOM 7759 C CZ . ARG B 1 453 ? -22.149 -21.769 57.556 1.00 105.51 ? 453 ARG B CZ 1 ATOM 7760 N NH1 . ARG B 1 453 ? -21.720 -22.713 56.720 1.00 105.34 ? 453 ARG B NH1 1 ATOM 7761 N NH2 . ARG B 1 453 ? -21.307 -20.830 57.973 1.00 105.64 ? 453 ARG B NH2 1 ATOM 7762 N N . ASP B 1 454 ? -29.296 -24.709 55.229 1.00 95.09 ? 454 ASP B N 1 ATOM 7763 C CA . ASP B 1 454 ? -30.420 -25.651 55.159 1.00 94.37 ? 454 ASP B CA 1 ATOM 7764 C C . ASP B 1 454 ? -30.545 -26.263 53.774 1.00 93.48 ? 454 ASP B C 1 ATOM 7765 O O . ASP B 1 454 ? -31.233 -27.282 53.565 1.00 93.06 ? 454 ASP B O 1 ATOM 7766 C CB . ASP B 1 454 ? -31.733 -24.973 55.555 1.00 94.63 ? 454 ASP B CB 1 ATOM 7767 C CG . ASP B 1 454 ? -32.676 -25.909 56.313 1.00 95.27 ? 454 ASP B CG 1 ATOM 7768 O OD1 . ASP B 1 454 ? -32.459 -27.143 56.323 1.00 95.57 ? 454 ASP B OD1 1 ATOM 7769 O OD2 . ASP B 1 454 ? -33.645 -25.391 56.910 1.00 96.62 ? 454 ASP B OD2 1 ATOM 7770 N N . ASN B 1 455 ? -29.879 -25.637 52.817 1.00 92.40 ? 455 ASN B N 1 ATOM 7771 C CA . ASN B 1 455 ? -29.720 -26.300 51.537 1.00 91.66 ? 455 ASN B CA 1 ATOM 7772 C C . ASN B 1 455 ? -30.959 -26.325 50.665 1.00 90.37 ? 455 ASN B C 1 ATOM 7773 O O . ASN B 1 455 ? -31.083 -27.182 49.795 1.00 90.26 ? 455 ASN B O 1 ATOM 7774 C CB . ASN B 1 455 ? -29.276 -27.744 51.769 1.00 92.08 ? 455 ASN B CB 1 ATOM 7775 C CG . ASN B 1 455 ? -27.881 -27.832 52.348 1.00 93.59 ? 455 ASN B CG 1 ATOM 7776 O OD1 . ASN B 1 455 ? -27.383 -26.870 52.962 1.00 95.26 ? 455 ASN B OD1 1 ATOM 7777 N ND2 . ASN B 1 455 ? -27.231 -28.982 52.152 1.00 94.39 ? 455 ASN B ND2 1 ATOM 7778 N N . TYR B 1 456 ? -31.903 -25.430 50.915 1.00 88.75 ? 456 TYR B N 1 ATOM 7779 C CA . TYR B 1 456 ? -32.879 -25.168 49.895 1.00 86.96 ? 456 TYR B CA 1 ATOM 7780 C C . TYR B 1 456 ? -32.152 -24.217 48.977 1.00 86.09 ? 456 TYR B C 1 ATOM 7781 O O . TYR B 1 456 ? -31.164 -23.617 49.388 1.00 86.04 ? 456 TYR B O 1 ATOM 7782 C CB . TYR B 1 456 ? -34.096 -24.483 50.475 1.00 86.84 ? 456 TYR B CB 1 ATOM 7783 C CG . TYR B 1 456 ? -34.959 -25.346 51.365 1.00 85.47 ? 456 TYR B CG 1 ATOM 7784 C CD1 . TYR B 1 456 ? -34.717 -25.418 52.723 1.00 84.08 ? 456 TYR B CD1 1 ATOM 7785 C CD2 . TYR B 1 456 ? -36.038 -26.057 50.848 1.00 83.94 ? 456 TYR B CD2 1 ATOM 7786 C CE1 . TYR B 1 456 ? -35.526 -26.174 53.548 1.00 83.91 ? 456 TYR B CE1 1 ATOM 7787 C CE2 . TYR B 1 456 ? -36.848 -26.825 51.660 1.00 83.19 ? 456 TYR B CE2 1 ATOM 7788 C CZ . TYR B 1 456 ? -36.591 -26.880 53.008 1.00 83.63 ? 456 TYR B CZ 1 ATOM 7789 O OH . TYR B 1 456 ? -37.398 -27.650 53.819 1.00 83.65 ? 456 TYR B OH 1 ATOM 7790 N N . THR B 1 457 ? -32.619 -24.078 47.743 1.00 84.91 ? 457 THR B N 1 ATOM 7791 C CA . THR B 1 457 ? -31.937 -23.234 46.772 1.00 83.75 ? 457 THR B CA 1 ATOM 7792 C C . THR B 1 457 ? -32.247 -21.755 46.952 1.00 83.21 ? 457 THR B C 1 ATOM 7793 O O . THR B 1 457 ? -33.088 -21.376 47.754 1.00 83.04 ? 457 THR B O 1 ATOM 7794 C CB . THR B 1 457 ? -32.322 -23.644 45.378 1.00 83.71 ? 457 THR B CB 1 ATOM 7795 O OG1 . THR B 1 457 ? -33.674 -23.239 45.123 1.00 83.61 ? 457 THR B OG1 1 ATOM 7796 C CG2 . THR B 1 457 ? -32.208 -25.152 45.272 1.00 83.69 ? 457 THR B CG2 1 ATOM 7797 N N . LYS B 1 458 ? -31.548 -20.914 46.206 1.00 82.83 ? 458 LYS B N 1 ATOM 7798 C CA . LYS B 1 458 ? -31.796 -19.489 46.294 1.00 82.49 ? 458 LYS B CA 1 ATOM 7799 C C . LYS B 1 458 ? -33.194 -19.233 45.761 1.00 81.75 ? 458 LYS B C 1 ATOM 7800 O O . LYS B 1 458 ? -34.004 -18.540 46.388 1.00 81.54 ? 458 LYS B O 1 ATOM 7801 C CB . LYS B 1 458 ? -30.769 -18.706 45.473 1.00 82.85 ? 458 LYS B CB 1 ATOM 7802 C CG . LYS B 1 458 ? -30.541 -17.299 46.005 1.00 84.17 ? 458 LYS B CG 1 ATOM 7803 C CD . LYS B 1 458 ? -30.224 -17.358 47.514 1.00 87.02 ? 458 LYS B CD 1 ATOM 7804 C CE . LYS B 1 458 ? -30.034 -15.962 48.113 1.00 87.72 ? 458 LYS B CE 1 ATOM 7805 N NZ . LYS B 1 458 ? -31.348 -15.297 48.313 1.00 87.92 ? 458 LYS B NZ 1 ATOM 7806 N N . ALA B 1 459 ? -33.463 -19.807 44.592 1.00 80.78 ? 459 ALA B N 1 ATOM 7807 C CA . ALA B 1 459 ? -34.795 -19.781 44.043 1.00 79.99 ? 459 ALA B CA 1 ATOM 7808 C C . ALA B 1 459 ? -35.795 -20.014 45.179 1.00 79.62 ? 459 ALA B C 1 ATOM 7809 O O . ALA B 1 459 ? -36.763 -19.263 45.354 1.00 79.70 ? 459 ALA B O 1 ATOM 7810 C CB . ALA B 1 459 ? -34.931 -20.853 42.983 1.00 79.73 ? 459 ALA B CB 1 ATOM 7811 N N . GLU B 1 460 ? -35.532 -21.049 45.970 1.00 78.95 ? 460 GLU B N 1 ATOM 7812 C CA . GLU B 1 460 ? -36.494 -21.514 46.950 1.00 78.27 ? 460 GLU B CA 1 ATOM 7813 C C . GLU B 1 460 ? -36.633 -20.568 48.131 1.00 78.04 ? 460 GLU B C 1 ATOM 7814 O O . GLU B 1 460 ? -37.729 -20.394 48.665 1.00 77.94 ? 460 GLU B O 1 ATOM 7815 C CB . GLU B 1 460 ? -36.135 -22.919 47.431 1.00 78.24 ? 460 GLU B CB 1 ATOM 7816 C CG . GLU B 1 460 ? -36.328 -24.002 46.395 1.00 78.08 ? 460 GLU B CG 1 ATOM 7817 C CD . GLU B 1 460 ? -36.106 -25.406 46.960 1.00 79.02 ? 460 GLU B CD 1 ATOM 7818 O OE1 . GLU B 1 460 ? -35.241 -25.577 47.845 1.00 78.83 ? 460 GLU B OE1 1 ATOM 7819 O OE2 . GLU B 1 460 ? -36.797 -26.351 46.513 1.00 79.87 ? 460 GLU B OE2 1 ATOM 7820 N N . GLU B 1 461 ? -35.525 -19.952 48.537 1.00 77.80 ? 461 GLU B N 1 ATOM 7821 C CA . GLU B 1 461 ? -35.573 -18.993 49.636 1.00 77.44 ? 461 GLU B CA 1 ATOM 7822 C C . GLU B 1 461 ? -36.463 -17.819 49.252 1.00 76.16 ? 461 GLU B C 1 ATOM 7823 O O . GLU B 1 461 ? -37.343 -17.399 50.002 1.00 75.70 ? 461 GLU B O 1 ATOM 7824 C CB . GLU B 1 461 ? -34.177 -18.471 50.009 1.00 78.09 ? 461 GLU B CB 1 ATOM 7825 C CG . GLU B 1 461 ? -34.218 -17.640 51.334 1.00 81.36 ? 461 GLU B CG 1 ATOM 7826 C CD . GLU B 1 461 ? -33.077 -16.601 51.515 1.00 84.28 ? 461 GLU B CD 1 ATOM 7827 O OE1 . GLU B 1 461 ? -32.885 -16.143 52.679 1.00 84.55 ? 461 GLU B OE1 1 ATOM 7828 O OE2 . GLU B 1 461 ? -32.388 -16.254 50.513 1.00 84.92 ? 461 GLU B OE2 1 ATOM 7829 N N . ILE B 1 462 ? -36.218 -17.293 48.067 1.00 74.97 ? 462 ILE B N 1 ATOM 7830 C CA . ILE B 1 462 ? -37.035 -16.227 47.560 1.00 74.23 ? 462 ILE B CA 1 ATOM 7831 C C . ILE B 1 462 ? -38.503 -16.621 47.686 1.00 73.36 ? 462 ILE B C 1 ATOM 7832 O O . ILE B 1 462 ? -39.278 -15.980 48.407 1.00 73.27 ? 462 ILE B O 1 ATOM 7833 C CB . ILE B 1 462 ? -36.680 -15.915 46.085 1.00 74.58 ? 462 ILE B CB 1 ATOM 7834 C CG1 . ILE B 1 462 ? -35.314 -15.229 46.029 1.00 75.18 ? 462 ILE B CG1 1 ATOM 7835 C CG2 . ILE B 1 462 ? -37.754 -15.028 45.421 1.00 74.06 ? 462 ILE B CG2 1 ATOM 7836 C CD1 . ILE B 1 462 ? -35.146 -14.128 47.132 1.00 75.46 ? 462 ILE B CD1 1 ATOM 7837 N N . LEU B 1 463 ? -38.873 -17.684 46.977 1.00 71.95 ? 463 LEU B N 1 ATOM 7838 C CA . LEU B 1 463 ? -40.260 -18.141 46.927 1.00 70.39 ? 463 LEU B CA 1 ATOM 7839 C C . LEU B 1 463 ? -40.928 -18.121 48.287 1.00 69.39 ? 463 LEU B C 1 ATOM 7840 O O . LEU B 1 463 ? -41.993 -17.530 48.452 1.00 68.95 ? 463 LEU B O 1 ATOM 7841 C CB . LEU B 1 463 ? -40.321 -19.561 46.372 1.00 70.35 ? 463 LEU B CB 1 ATOM 7842 C CG . LEU B 1 463 ? -41.726 -20.129 46.214 1.00 69.54 ? 463 LEU B CG 1 ATOM 7843 C CD1 . LEU B 1 463 ? -42.560 -19.212 45.325 1.00 68.81 ? 463 LEU B CD1 1 ATOM 7844 C CD2 . LEU B 1 463 ? -41.641 -21.535 45.634 1.00 69.03 ? 463 LEU B CD2 1 ATOM 7845 N N . SER B 1 464 ? -40.297 -18.790 49.250 1.00 68.33 ? 464 SER B N 1 ATOM 7846 C CA . SER B 1 464 ? -40.829 -18.890 50.600 1.00 67.27 ? 464 SER B CA 1 ATOM 7847 C C . SER B 1 464 ? -41.037 -17.510 51.203 1.00 66.87 ? 464 SER B C 1 ATOM 7848 O O . SER B 1 464 ? -42.072 -17.218 51.803 1.00 66.31 ? 464 SER B O 1 ATOM 7849 C CB . SER B 1 464 ? -39.873 -19.681 51.472 1.00 66.93 ? 464 SER B CB 1 ATOM 7850 O OG . SER B 1 464 ? -40.454 -19.836 52.743 1.00 66.88 ? 464 SER B OG 1 ATOM 7851 N N . ARG B 1 465 ? -40.030 -16.659 51.018 1.00 66.80 ? 465 ARG B N 1 ATOM 7852 C CA . ARG B 1 465 ? -40.084 -15.265 51.470 1.00 66.51 ? 465 ARG B CA 1 ATOM 7853 C C . ARG B 1 465 ? -41.338 -14.589 50.908 1.00 65.48 ? 465 ARG B C 1 ATOM 7854 O O . ARG B 1 465 ? -42.031 -13.825 51.591 1.00 65.42 ? 465 ARG B O 1 ATOM 7855 C CB . ARG B 1 465 ? -38.811 -14.495 51.041 1.00 66.84 ? 465 ARG B CB 1 ATOM 7856 C CG . ARG B 1 465 ? -38.737 -13.027 51.562 1.00 69.05 ? 465 ARG B CG 1 ATOM 7857 C CD . ARG B 1 465 ? -38.640 -12.953 53.122 1.00 72.33 ? 465 ARG B CD 1 ATOM 7858 N NE . ARG B 1 465 ? -39.149 -11.701 53.707 1.00 73.69 ? 465 ARG B NE 1 ATOM 7859 C CZ . ARG B 1 465 ? -40.378 -11.550 54.208 1.00 75.23 ? 465 ARG B CZ 1 ATOM 7860 N NH1 . ARG B 1 465 ? -41.236 -12.565 54.203 1.00 76.25 ? 465 ARG B NH1 1 ATOM 7861 N NH2 . ARG B 1 465 ? -40.763 -10.383 54.710 1.00 76.13 ? 465 ARG B NH2 1 ATOM 7862 N N . SER B 1 466 ? -41.628 -14.883 49.647 1.00 64.28 ? 466 SER B N 1 ATOM 7863 C CA . SER B 1 466 ? -42.774 -14.287 49.000 1.00 62.70 ? 466 SER B CA 1 ATOM 7864 C C . SER B 1 466 ? -44.092 -14.796 49.585 1.00 61.70 ? 466 SER B C 1 ATOM 7865 O O . SER B 1 466 ? -44.968 -14.011 49.962 1.00 61.31 ? 466 SER B O 1 ATOM 7866 C CB . SER B 1 466 ? -42.706 -14.576 47.528 1.00 62.39 ? 466 SER B CB 1 ATOM 7867 O OG . SER B 1 466 ? -43.443 -13.589 46.877 1.00 63.12 ? 466 SER B OG 1 ATOM 7868 N N . ILE B 1 467 ? -44.211 -16.118 49.667 1.00 60.76 ? 467 ILE B N 1 ATOM 7869 C CA . ILE B 1 467 ? -45.397 -16.769 50.234 1.00 59.54 ? 467 ILE B CA 1 ATOM 7870 C C . ILE B 1 467 ? -45.610 -16.277 51.665 1.00 59.27 ? 467 ILE B C 1 ATOM 7871 O O . ILE B 1 467 ? -46.672 -15.753 52.039 1.00 59.21 ? 467 ILE B O 1 ATOM 7872 C CB . ILE B 1 467 ? -45.240 -18.309 50.198 1.00 59.09 ? 467 ILE B CB 1 ATOM 7873 C CG1 . ILE B 1 467 ? -45.163 -18.777 48.741 1.00 58.28 ? 467 ILE B CG1 1 ATOM 7874 C CG2 . ILE B 1 467 ? -46.362 -18.994 50.935 1.00 58.17 ? 467 ILE B CG2 1 ATOM 7875 C CD1 . ILE B 1 467 ? -44.811 -20.225 48.573 1.00 56.69 ? 467 ILE B CD1 1 ATOM 7876 N N . VAL B 1 468 ? -44.574 -16.425 52.467 1.00 58.73 ? 468 VAL B N 1 ATOM 7877 C CA . VAL B 1 468 ? -44.660 -15.999 53.840 1.00 58.16 ? 468 VAL B CA 1 ATOM 7878 C C . VAL B 1 468 ? -45.273 -14.602 53.911 1.00 57.92 ? 468 VAL B C 1 ATOM 7879 O O . VAL B 1 468 ? -46.187 -14.355 54.695 1.00 58.07 ? 468 VAL B O 1 ATOM 7880 C CB . VAL B 1 468 ? -43.273 -16.016 54.496 1.00 58.28 ? 468 VAL B CB 1 ATOM 7881 C CG1 . VAL B 1 468 ? -43.313 -15.232 55.798 1.00 57.79 ? 468 VAL B CG1 1 ATOM 7882 C CG2 . VAL B 1 468 ? -42.789 -17.485 54.691 1.00 57.54 ? 468 VAL B CG2 1 ATOM 7883 N N . LYS B 1 469 ? -44.776 -13.694 53.079 1.00 57.51 ? 469 LYS B N 1 ATOM 7884 C CA . LYS B 1 469 ? -45.300 -12.333 53.022 1.00 57.25 ? 469 LYS B CA 1 ATOM 7885 C C . LYS B 1 469 ? -46.781 -12.301 52.636 1.00 56.97 ? 469 LYS B C 1 ATOM 7886 O O . LYS B 1 469 ? -47.604 -11.638 53.282 1.00 56.64 ? 469 LYS B O 1 ATOM 7887 C CB . LYS B 1 469 ? -44.501 -11.511 52.001 1.00 57.43 ? 469 LYS B CB 1 ATOM 7888 C CG . LYS B 1 469 ? -45.132 -10.158 51.650 1.00 57.66 ? 469 LYS B CG 1 ATOM 7889 C CD . LYS B 1 469 ? -45.303 -9.289 52.888 1.00 57.25 ? 469 LYS B CD 1 ATOM 7890 C CE . LYS B 1 469 ? -44.022 -9.239 53.697 1.00 56.74 ? 469 LYS B CE 1 ATOM 7891 N NZ . LYS B 1 469 ? -44.110 -8.211 54.727 1.00 56.84 ? 469 LYS B NZ 1 ATOM 7892 N N . ARG B 1 470 ? -47.105 -13.011 51.559 1.00 56.52 ? 470 ARG B N 1 ATOM 7893 C CA . ARG B 1 470 ? -48.453 -12.968 51.020 1.00 56.01 ? 470 ARG B CA 1 ATOM 7894 C C . ARG B 1 470 ? -49.411 -13.496 52.065 1.00 55.64 ? 470 ARG B C 1 ATOM 7895 O O . ARG B 1 470 ? -50.436 -12.876 52.337 1.00 55.46 ? 470 ARG B O 1 ATOM 7896 C CB . ARG B 1 470 ? -48.563 -13.785 49.729 1.00 55.84 ? 470 ARG B CB 1 ATOM 7897 C CG . ARG B 1 470 ? -47.788 -13.234 48.559 1.00 54.47 ? 470 ARG B CG 1 ATOM 7898 C CD . ARG B 1 470 ? -48.175 -14.007 47.302 1.00 52.92 ? 470 ARG B CD 1 ATOM 7899 N NE . ARG B 1 470 ? -47.632 -13.440 46.068 1.00 51.09 ? 470 ARG B NE 1 ATOM 7900 C CZ . ARG B 1 470 ? -48.222 -12.478 45.360 1.00 50.95 ? 470 ARG B CZ 1 ATOM 7901 N NH1 . ARG B 1 470 ? -47.655 -12.036 44.252 1.00 51.77 ? 470 ARG B NH1 1 ATOM 7902 N NH2 . ARG B 1 470 ? -49.370 -11.946 45.751 1.00 50.02 ? 470 ARG B NH2 1 ATOM 7903 N N . TRP B 1 471 ? -49.077 -14.642 52.639 1.00 55.42 ? 471 TRP B N 1 ATOM 7904 C CA . TRP B 1 471 ? -49.879 -15.176 53.723 1.00 56.15 ? 471 TRP B CA 1 ATOM 7905 C C . TRP B 1 471 ? -49.998 -14.133 54.838 1.00 56.57 ? 471 TRP B C 1 ATOM 7906 O O . TRP B 1 471 ? -51.107 -13.688 55.185 1.00 56.67 ? 471 TRP B O 1 ATOM 7907 C CB . TRP B 1 471 ? -49.233 -16.424 54.297 1.00 55.91 ? 471 TRP B CB 1 ATOM 7908 C CG . TRP B 1 471 ? -49.735 -17.718 53.742 1.00 56.18 ? 471 TRP B CG 1 ATOM 7909 C CD1 . TRP B 1 471 ? -50.173 -18.807 54.455 1.00 56.93 ? 471 TRP B CD1 1 ATOM 7910 C CD2 . TRP B 1 471 ? -49.837 -18.082 52.369 1.00 55.55 ? 471 TRP B CD2 1 ATOM 7911 N NE1 . TRP B 1 471 ? -50.533 -19.821 53.603 1.00 56.69 ? 471 TRP B NE1 1 ATOM 7912 C CE2 . TRP B 1 471 ? -50.337 -19.395 52.318 1.00 55.89 ? 471 TRP B CE2 1 ATOM 7913 C CE3 . TRP B 1 471 ? -49.550 -17.429 51.175 1.00 54.46 ? 471 TRP B CE3 1 ATOM 7914 C CZ2 . TRP B 1 471 ? -50.554 -20.053 51.126 1.00 55.53 ? 471 TRP B CZ2 1 ATOM 7915 C CZ3 . TRP B 1 471 ? -49.765 -18.088 49.995 1.00 53.84 ? 471 TRP B CZ3 1 ATOM 7916 C CH2 . TRP B 1 471 ? -50.260 -19.379 49.971 1.00 54.12 ? 471 TRP B CH2 1 ATOM 7917 N N . ALA B 1 472 ? -48.846 -13.752 55.390 1.00 56.66 ? 472 ALA B N 1 ATOM 7918 C CA . ALA B 1 472 ? -48.775 -12.748 56.425 1.00 56.95 ? 472 ALA B CA 1 ATOM 7919 C C . ALA B 1 472 ? -49.701 -11.560 56.131 1.00 57.52 ? 472 ALA B C 1 ATOM 7920 O O . ALA B 1 472 ? -50.588 -11.238 56.936 1.00 57.70 ? 472 ALA B O 1 ATOM 7921 C CB . ALA B 1 472 ? -47.353 -12.287 56.571 1.00 57.10 ? 472 ALA B CB 1 ATOM 7922 N N . ASN B 1 473 ? -49.482 -10.911 54.984 1.00 57.93 ? 473 ASN B N 1 ATOM 7923 C CA . ASN B 1 473 ? -50.372 -9.877 54.481 1.00 58.29 ? 473 ASN B CA 1 ATOM 7924 C C . ASN B 1 473 ? -51.841 -10.287 54.465 1.00 58.37 ? 473 ASN B C 1 ATOM 7925 O O . ASN B 1 473 ? -52.705 -9.518 54.899 1.00 58.78 ? 473 ASN B O 1 ATOM 7926 C CB . ASN B 1 473 ? -49.953 -9.490 53.079 1.00 58.60 ? 473 ASN B CB 1 ATOM 7927 C CG . ASN B 1 473 ? -49.040 -8.303 53.071 1.00 60.72 ? 473 ASN B CG 1 ATOM 7928 O OD1 . ASN B 1 473 ? -49.126 -7.449 53.961 1.00 63.99 ? 473 ASN B OD1 1 ATOM 7929 N ND2 . ASN B 1 473 ? -48.157 -8.221 52.065 1.00 61.46 ? 473 ASN B ND2 1 ATOM 7930 N N . PHE B 1 474 ? -52.131 -11.491 53.964 1.00 58.00 ? 474 PHE B N 1 ATOM 7931 C CA . PHE B 1 474 ? -53.505 -11.925 53.900 1.00 57.68 ? 474 PHE B CA 1 ATOM 7932 C C . PHE B 1 474 ? -54.098 -11.937 55.293 1.00 58.03 ? 474 PHE B C 1 ATOM 7933 O O . PHE B 1 474 ? -55.225 -11.471 55.497 1.00 58.06 ? 474 PHE B O 1 ATOM 7934 C CB . PHE B 1 474 ? -53.686 -13.307 53.257 1.00 57.43 ? 474 PHE B CB 1 ATOM 7935 C CG . PHE B 1 474 ? -55.098 -13.813 53.390 1.00 56.69 ? 474 PHE B CG 1 ATOM 7936 C CD1 . PHE B 1 474 ? -56.087 -13.390 52.515 1.00 54.50 ? 474 PHE B CD1 1 ATOM 7937 C CD2 . PHE B 1 474 ? -55.459 -14.626 54.461 1.00 55.41 ? 474 PHE B CD2 1 ATOM 7938 C CE1 . PHE B 1 474 ? -57.405 -13.817 52.685 1.00 54.29 ? 474 PHE B CE1 1 ATOM 7939 C CE2 . PHE B 1 474 ? -56.775 -15.045 54.636 1.00 54.08 ? 474 PHE B CE2 1 ATOM 7940 C CZ . PHE B 1 474 ? -57.750 -14.643 53.751 1.00 53.02 ? 474 PHE B CZ 1 ATOM 7941 N N . ALA B 1 475 ? -53.346 -12.497 56.244 1.00 58.29 ? 475 ALA B N 1 ATOM 7942 C CA . ALA B 1 475 ? -53.762 -12.541 57.651 1.00 58.32 ? 475 ALA B CA 1 ATOM 7943 C C . ALA B 1 475 ? -54.038 -11.131 58.148 1.00 58.59 ? 475 ALA B C 1 ATOM 7944 O O . ALA B 1 475 ? -55.092 -10.866 58.733 1.00 58.69 ? 475 ALA B O 1 ATOM 7945 C CB . ALA B 1 475 ? -52.689 -13.187 58.505 1.00 58.16 ? 475 ALA B CB 1 ATOM 7946 N N . LYS B 1 476 ? -53.096 -10.224 57.896 1.00 58.66 ? 476 LYS B N 1 ATOM 7947 C CA . LYS B 1 476 ? -53.192 -8.865 58.415 1.00 59.16 ? 476 LYS B CA 1 ATOM 7948 C C . LYS B 1 476 ? -54.267 -8.033 57.737 1.00 59.39 ? 476 LYS B C 1 ATOM 7949 O O . LYS B 1 476 ? -55.112 -7.425 58.382 1.00 59.67 ? 476 LYS B O 1 ATOM 7950 C CB . LYS B 1 476 ? -51.848 -8.145 58.297 1.00 59.29 ? 476 LYS B CB 1 ATOM 7951 C CG . LYS B 1 476 ? -50.791 -8.592 59.332 1.00 59.14 ? 476 LYS B CG 1 ATOM 7952 C CD . LYS B 1 476 ? -49.412 -8.043 58.927 1.00 58.95 ? 476 LYS B CD 1 ATOM 7953 C CE . LYS B 1 476 ? -48.298 -8.514 59.868 1.00 59.53 ? 476 LYS B CE 1 ATOM 7954 N NZ . LYS B 1 476 ? -46.913 -8.381 59.267 1.00 58.81 ? 476 LYS B NZ 1 ATOM 7955 N N . TYR B 1 477 ? -54.253 -7.993 56.427 1.00 59.82 ? 477 TYR B N 1 ATOM 7956 C CA . TYR B 1 477 ? -55.124 -7.044 55.778 1.00 60.14 ? 477 TYR B CA 1 ATOM 7957 C C . TYR B 1 477 ? -56.188 -7.667 54.920 1.00 59.90 ? 477 TYR B C 1 ATOM 7958 O O . TYR B 1 477 ? -56.979 -6.949 54.338 1.00 59.56 ? 477 TYR B O 1 ATOM 7959 C CB . TYR B 1 477 ? -54.282 -6.100 54.948 1.00 60.48 ? 477 TYR B CB 1 ATOM 7960 C CG . TYR B 1 477 ? -53.052 -5.658 55.696 1.00 62.22 ? 477 TYR B CG 1 ATOM 7961 C CD1 . TYR B 1 477 ? -51.776 -5.921 55.195 1.00 63.78 ? 477 TYR B CD1 1 ATOM 7962 C CD2 . TYR B 1 477 ? -53.164 -4.995 56.920 1.00 62.65 ? 477 TYR B CD2 1 ATOM 7963 C CE1 . TYR B 1 477 ? -50.638 -5.500 55.885 1.00 64.78 ? 477 TYR B CE1 1 ATOM 7964 C CE2 . TYR B 1 477 ? -52.048 -4.570 57.603 1.00 63.66 ? 477 TYR B CE2 1 ATOM 7965 C CZ . TYR B 1 477 ? -50.785 -4.830 57.090 1.00 64.75 ? 477 TYR B CZ 1 ATOM 7966 O OH . TYR B 1 477 ? -49.667 -4.417 57.771 1.00 65.76 ? 477 TYR B OH 1 ATOM 7967 N N . GLY B 1 478 ? -56.214 -8.993 54.840 1.00 60.14 ? 478 GLY B N 1 ATOM 7968 C CA . GLY B 1 478 ? -57.205 -9.683 54.002 1.00 60.72 ? 478 GLY B CA 1 ATOM 7969 C C . GLY B 1 478 ? -56.893 -9.564 52.511 1.00 61.22 ? 478 GLY B C 1 ATOM 7970 O O . GLY B 1 478 ? -57.802 -9.508 51.665 1.00 61.31 ? 478 GLY B O 1 ATOM 7971 N N . ASN B 1 479 ? -55.600 -9.520 52.193 1.00 61.22 ? 479 ASN B N 1 ATOM 7972 C CA . ASN B 1 479 ? -55.156 -9.327 50.836 1.00 61.01 ? 479 ASN B CA 1 ATOM 7973 C C . ASN B 1 479 ? -53.740 -9.911 50.677 1.00 61.50 ? 479 ASN B C 1 ATOM 7974 O O . ASN B 1 479 ? -52.778 -9.397 51.258 1.00 61.17 ? 479 ASN B O 1 ATOM 7975 C CB . ASN B 1 479 ? -55.207 -7.842 50.509 1.00 60.62 ? 479 ASN B CB 1 ATOM 7976 C CG . ASN B 1 479 ? -55.385 -7.582 49.036 1.00 60.34 ? 479 ASN B CG 1 ATOM 7977 O OD1 . ASN B 1 479 ? -54.926 -8.359 48.195 1.00 59.93 ? 479 ASN B OD1 1 ATOM 7978 N ND2 . ASN B 1 479 ? -56.039 -6.476 48.708 1.00 60.01 ? 479 ASN B ND2 1 ATOM 7979 N N . PRO B 1 480 ? -53.625 -11.012 49.910 1.00 61.96 ? 480 PRO B N 1 ATOM 7980 C CA . PRO B 1 480 ? -52.399 -11.770 49.777 1.00 62.65 ? 480 PRO B CA 1 ATOM 7981 C C . PRO B 1 480 ? -51.446 -11.200 48.749 1.00 63.60 ? 480 PRO B C 1 ATOM 7982 O O . PRO B 1 480 ? -50.840 -11.958 47.996 1.00 63.81 ? 480 PRO B O 1 ATOM 7983 C CB . PRO B 1 480 ? -52.894 -13.130 49.279 1.00 62.58 ? 480 PRO B CB 1 ATOM 7984 C CG . PRO B 1 480 ? -54.084 -12.819 48.490 1.00 61.87 ? 480 PRO B CG 1 ATOM 7985 C CD . PRO B 1 480 ? -54.748 -11.674 49.221 1.00 61.99 ? 480 PRO B CD 1 ATOM 7986 N N . GLN B 1 481 ? -51.306 -9.884 48.715 1.00 64.73 ? 481 GLN B N 1 ATOM 7987 C CA . GLN B 1 481 ? -50.346 -9.249 47.816 1.00 65.80 ? 481 GLN B CA 1 ATOM 7988 C C . GLN B 1 481 ? -48.925 -9.212 48.388 1.00 66.79 ? 481 GLN B C 1 ATOM 7989 O O . GLN B 1 481 ? -48.726 -9.288 49.599 1.00 66.84 ? 481 GLN B O 1 ATOM 7990 C CB . GLN B 1 481 ? -50.813 -7.838 47.485 1.00 65.61 ? 481 GLN B CB 1 ATOM 7991 C CG . GLN B 1 481 ? -52.251 -7.807 47.016 1.00 65.10 ? 481 GLN B CG 1 ATOM 7992 C CD . GLN B 1 481 ? -52.459 -8.720 45.830 1.00 65.21 ? 481 GLN B CD 1 ATOM 7993 O OE1 . GLN B 1 481 ? -51.564 -8.887 44.982 1.00 65.86 ? 481 GLN B OE1 1 ATOM 7994 N NE2 . GLN B 1 481 ? -53.640 -9.312 45.748 1.00 63.89 ? 481 GLN B NE2 1 ATOM 7995 N N . GLU B 1 482 ? -47.940 -9.137 47.499 1.00 68.14 ? 482 GLU B N 1 ATOM 7996 C CA . GLU B 1 482 ? -46.571 -8.846 47.878 1.00 69.43 ? 482 GLU B CA 1 ATOM 7997 C C . GLU B 1 482 ? -46.325 -7.548 47.163 1.00 70.59 ? 482 GLU B C 1 ATOM 7998 O O . GLU B 1 482 ? -46.113 -7.546 45.951 1.00 70.97 ? 482 GLU B O 1 ATOM 7999 C CB . GLU B 1 482 ? -45.624 -9.910 47.346 1.00 69.40 ? 482 GLU B CB 1 ATOM 8000 C CG . GLU B 1 482 ? -44.195 -9.826 47.879 1.00 70.35 ? 482 GLU B CG 1 ATOM 8001 C CD . GLU B 1 482 ? -43.551 -8.481 47.602 1.00 72.01 ? 482 GLU B CD 1 ATOM 8002 O OE1 . GLU B 1 482 ? -43.438 -7.682 48.560 1.00 73.88 ? 482 GLU B OE1 1 ATOM 8003 O OE2 . GLU B 1 482 ? -43.182 -8.207 46.433 1.00 71.47 ? 482 GLU B OE2 1 ATOM 8004 N N . THR B 1 483 ? -46.380 -6.437 47.892 1.00 72.06 ? 483 THR B N 1 ATOM 8005 C CA . THR B 1 483 ? -46.505 -5.131 47.244 1.00 73.22 ? 483 THR B CA 1 ATOM 8006 C C . THR B 1 483 ? -45.176 -4.498 46.877 1.00 74.33 ? 483 THR B C 1 ATOM 8007 O O . THR B 1 483 ? -45.146 -3.526 46.139 1.00 74.79 ? 483 THR B O 1 ATOM 8008 C CB . THR B 1 483 ? -47.244 -4.134 48.131 1.00 72.96 ? 483 THR B CB 1 ATOM 8009 O OG1 . THR B 1 483 ? -46.330 -3.615 49.098 1.00 73.32 ? 483 THR B OG1 1 ATOM 8010 C CG2 . THR B 1 483 ? -48.390 -4.801 48.850 1.00 72.81 ? 483 THR B CG2 1 ATOM 8011 N N . GLN B 1 484 ? -44.071 -5.039 47.370 1.00 75.71 ? 484 GLN B N 1 ATOM 8012 C CA . GLN B 1 484 ? -42.818 -4.304 47.267 1.00 77.02 ? 484 GLN B CA 1 ATOM 8013 C C . GLN B 1 484 ? -41.839 -4.746 46.215 1.00 77.73 ? 484 GLN B C 1 ATOM 8014 O O . GLN B 1 484 ? -41.138 -3.900 45.657 1.00 77.82 ? 484 GLN B O 1 ATOM 8015 C CB . GLN B 1 484 ? -42.114 -4.254 48.603 1.00 77.17 ? 484 GLN B CB 1 ATOM 8016 C CG . GLN B 1 484 ? -42.637 -3.156 49.474 1.00 79.10 ? 484 GLN B CG 1 ATOM 8017 C CD . GLN B 1 484 ? -42.350 -3.424 50.923 1.00 81.60 ? 484 GLN B CD 1 ATOM 8018 O OE1 . GLN B 1 484 ? -42.393 -2.508 51.740 1.00 83.21 ? 484 GLN B OE1 1 ATOM 8019 N NE2 . GLN B 1 484 ? -42.045 -4.688 51.258 1.00 81.20 ? 484 GLN B NE2 1 ATOM 8020 N N . ASN B 1 485 ? -41.762 -6.048 45.946 1.00 78.68 ? 485 ASN B N 1 ATOM 8021 C CA . ASN B 1 485 ? -40.779 -6.533 44.978 1.00 79.72 ? 485 ASN B CA 1 ATOM 8022 C C . ASN B 1 485 ? -41.331 -6.732 43.562 1.00 79.51 ? 485 ASN B C 1 ATOM 8023 O O . ASN B 1 485 ? -41.082 -7.764 42.934 1.00 79.70 ? 485 ASN B O 1 ATOM 8024 C CB . ASN B 1 485 ? -40.062 -7.775 45.497 1.00 80.32 ? 485 ASN B CB 1 ATOM 8025 C CG . ASN B 1 485 ? -39.174 -7.473 46.692 1.00 83.88 ? 485 ASN B CG 1 ATOM 8026 O OD1 . ASN B 1 485 ? -38.988 -6.308 47.068 1.00 84.04 ? 485 ASN B OD1 1 ATOM 8027 N ND2 . ASN B 1 485 ? -38.627 -8.532 47.302 1.00 90.08 ? 485 ASN B ND2 1 ATOM 8028 N N . ASN B 1 486 ? -42.074 -5.725 43.080 1.00 79.34 ? 486 ASN B N 1 ATOM 8029 C CA . ASN B 1 486 ? -42.579 -5.643 41.703 1.00 78.68 ? 486 ASN B CA 1 ATOM 8030 C C . ASN B 1 486 ? -43.350 -6.923 41.293 1.00 78.33 ? 486 ASN B C 1 ATOM 8031 O O . ASN B 1 486 ? -43.237 -7.411 40.151 1.00 78.45 ? 486 ASN B O 1 ATOM 8032 C CB . ASN B 1 486 ? -41.415 -5.320 40.735 1.00 78.38 ? 486 ASN B CB 1 ATOM 8033 N N . SER B 1 487 ? -44.139 -7.451 42.234 1.00 77.35 ? 487 SER B N 1 ATOM 8034 C CA . SER B 1 487 ? -44.701 -8.799 42.109 1.00 76.49 ? 487 SER B CA 1 ATOM 8035 C C . SER B 1 487 ? -45.956 -8.845 41.247 1.00 75.95 ? 487 SER B C 1 ATOM 8036 O O . SER B 1 487 ? -46.493 -7.801 40.879 1.00 76.29 ? 487 SER B O 1 ATOM 8037 C CB . SER B 1 487 ? -44.990 -9.398 43.488 1.00 76.30 ? 487 SER B CB 1 ATOM 8038 O OG . SER B 1 487 ? -43.785 -9.579 44.220 1.00 75.99 ? 487 SER B OG 1 ATOM 8039 N N . THR B 1 488 ? -46.401 -10.055 40.901 1.00 74.83 ? 488 THR B N 1 ATOM 8040 C CA . THR B 1 488 ? -47.661 -10.222 40.186 1.00 73.33 ? 488 THR B CA 1 ATOM 8041 C C . THR B 1 488 ? -48.786 -9.956 41.171 1.00 72.59 ? 488 THR B C 1 ATOM 8042 O O . THR B 1 488 ? -48.782 -10.493 42.288 1.00 72.55 ? 488 THR B O 1 ATOM 8043 C CB . THR B 1 488 ? -47.840 -11.646 39.663 1.00 73.32 ? 488 THR B CB 1 ATOM 8044 O OG1 . THR B 1 488 ? -46.864 -11.913 38.649 1.00 73.13 ? 488 THR B OG1 1 ATOM 8045 C CG2 . THR B 1 488 ? -49.243 -11.818 39.104 1.00 72.76 ? 488 THR B CG2 1 ATOM 8046 N N . SER B 1 489 ? -49.732 -9.111 40.767 1.00 71.24 ? 489 SER B N 1 ATOM 8047 C CA . SER B 1 489 ? -50.928 -8.857 41.564 1.00 69.85 ? 489 SER B CA 1 ATOM 8048 C C . SER B 1 489 ? -51.767 -10.138 41.633 1.00 68.85 ? 489 SER B C 1 ATOM 8049 O O . SER B 1 489 ? -51.949 -10.826 40.627 1.00 68.91 ? 489 SER B O 1 ATOM 8050 C CB . SER B 1 489 ? -51.732 -7.750 40.903 1.00 69.92 ? 489 SER B CB 1 ATOM 8051 O OG . SER B 1 489 ? -52.292 -6.897 41.867 1.00 70.51 ? 489 SER B OG 1 ATOM 8052 N N . TRP B 1 490 ? -52.270 -10.477 42.813 1.00 67.69 ? 490 TRP B N 1 ATOM 8053 C CA . TRP B 1 490 ? -53.037 -11.720 42.968 1.00 66.40 ? 490 TRP B CA 1 ATOM 8054 C C . TRP B 1 490 ? -54.510 -11.385 42.926 1.00 66.01 ? 490 TRP B C 1 ATOM 8055 O O . TRP B 1 490 ? -55.051 -10.908 43.928 1.00 65.89 ? 490 TRP B O 1 ATOM 8056 C CB . TRP B 1 490 ? -52.716 -12.382 44.301 1.00 65.98 ? 490 TRP B CB 1 ATOM 8057 C CG . TRP B 1 490 ? -53.347 -13.718 44.527 1.00 64.79 ? 490 TRP B CG 1 ATOM 8058 C CD1 . TRP B 1 490 ? -54.426 -14.245 43.885 1.00 64.10 ? 490 TRP B CD1 1 ATOM 8059 C CD2 . TRP B 1 490 ? -52.960 -14.681 45.515 1.00 64.45 ? 490 TRP B CD2 1 ATOM 8060 N NE1 . TRP B 1 490 ? -54.720 -15.491 44.394 1.00 63.65 ? 490 TRP B NE1 1 ATOM 8061 C CE2 . TRP B 1 490 ? -53.830 -15.778 45.397 1.00 63.81 ? 490 TRP B CE2 1 ATOM 8062 C CE3 . TRP B 1 490 ? -51.954 -14.720 46.488 1.00 64.57 ? 490 TRP B CE3 1 ATOM 8063 C CZ2 . TRP B 1 490 ? -53.720 -16.907 46.212 1.00 63.48 ? 490 TRP B CZ2 1 ATOM 8064 C CZ3 . TRP B 1 490 ? -51.846 -15.845 47.290 1.00 63.67 ? 490 TRP B CZ3 1 ATOM 8065 C CH2 . TRP B 1 490 ? -52.721 -16.920 47.147 1.00 62.80 ? 490 TRP B CH2 1 ATOM 8066 N N . PRO B 1 491 ? -55.165 -11.645 41.774 1.00 65.44 ? 491 PRO B N 1 ATOM 8067 C CA . PRO B 1 491 ? -56.541 -11.282 41.474 1.00 65.51 ? 491 PRO B CA 1 ATOM 8068 C C . PRO B 1 491 ? -57.539 -11.977 42.385 1.00 66.20 ? 491 PRO B C 1 ATOM 8069 O O . PRO B 1 491 ? -57.324 -13.127 42.773 1.00 66.83 ? 491 PRO B O 1 ATOM 8070 C CB . PRO B 1 491 ? -56.721 -11.833 40.068 1.00 65.29 ? 491 PRO B CB 1 ATOM 8071 C CG . PRO B 1 491 ? -55.834 -12.979 40.029 1.00 64.66 ? 491 PRO B CG 1 ATOM 8072 C CD . PRO B 1 491 ? -54.614 -12.506 40.721 1.00 64.94 ? 491 PRO B CD 1 ATOM 8073 N N . VAL B 1 492 ? -58.629 -11.299 42.727 1.00 66.64 ? 492 VAL B N 1 ATOM 8074 C CA . VAL B 1 492 ? -59.710 -11.950 43.465 1.00 66.90 ? 492 VAL B CA 1 ATOM 8075 C C . VAL B 1 492 ? -60.330 -13.074 42.613 1.00 67.53 ? 492 VAL B C 1 ATOM 8076 O O . VAL B 1 492 ? -60.446 -12.944 41.384 1.00 67.38 ? 492 VAL B O 1 ATOM 8077 C CB . VAL B 1 492 ? -60.794 -10.930 43.884 1.00 66.77 ? 492 VAL B CB 1 ATOM 8078 C CG1 . VAL B 1 492 ? -62.081 -11.630 44.237 1.00 66.86 ? 492 VAL B CG1 1 ATOM 8079 C CG2 . VAL B 1 492 ? -60.321 -10.096 45.063 1.00 65.95 ? 492 VAL B CG2 1 ATOM 8080 N N . PHE B 1 493 ? -60.710 -14.175 43.260 1.00 68.21 ? 493 PHE B N 1 ATOM 8081 C CA . PHE B 1 493 ? -61.335 -15.311 42.574 1.00 68.96 ? 493 PHE B CA 1 ATOM 8082 C C . PHE B 1 493 ? -62.836 -15.096 42.434 1.00 70.14 ? 493 PHE B C 1 ATOM 8083 O O . PHE B 1 493 ? -63.580 -15.290 43.392 1.00 70.39 ? 493 PHE B O 1 ATOM 8084 C CB . PHE B 1 493 ? -61.083 -16.603 43.356 1.00 68.55 ? 493 PHE B CB 1 ATOM 8085 C CG . PHE B 1 493 ? -61.647 -17.842 42.703 1.00 67.40 ? 493 PHE B CG 1 ATOM 8086 C CD1 . PHE B 1 493 ? -62.947 -18.257 42.956 1.00 66.65 ? 493 PHE B CD1 1 ATOM 8087 C CD2 . PHE B 1 493 ? -60.867 -18.609 41.855 1.00 66.36 ? 493 PHE B CD2 1 ATOM 8088 C CE1 . PHE B 1 493 ? -63.459 -19.400 42.354 1.00 65.73 ? 493 PHE B CE1 1 ATOM 8089 C CE2 . PHE B 1 493 ? -61.376 -19.754 41.251 1.00 65.42 ? 493 PHE B CE2 1 ATOM 8090 C CZ . PHE B 1 493 ? -62.669 -20.144 41.497 1.00 65.40 ? 493 PHE B CZ 1 ATOM 8091 N N . LYS B 1 494 ? -63.284 -14.692 41.249 1.00 71.62 ? 494 LYS B N 1 ATOM 8092 C CA . LYS B 1 494 ? -64.714 -14.514 40.989 1.00 73.11 ? 494 LYS B CA 1 ATOM 8093 C C . LYS B 1 494 ? -65.303 -15.806 40.450 1.00 73.32 ? 494 LYS B C 1 ATOM 8094 O O . LYS B 1 494 ? -64.595 -16.617 39.845 1.00 72.98 ? 494 LYS B O 1 ATOM 8095 C CB . LYS B 1 494 ? -64.940 -13.391 39.970 1.00 73.88 ? 494 LYS B CB 1 ATOM 8096 C CG . LYS B 1 494 ? -65.679 -12.138 40.469 1.00 76.26 ? 494 LYS B CG 1 ATOM 8097 C CD . LYS B 1 494 ? -66.694 -11.671 39.375 1.00 81.44 ? 494 LYS B CD 1 ATOM 8098 C CE . LYS B 1 494 ? -67.496 -10.397 39.724 1.00 83.37 ? 494 LYS B CE 1 ATOM 8099 N NZ . LYS B 1 494 ? -66.877 -9.147 39.169 1.00 84.45 ? 494 LYS B NZ 1 ATOM 8100 N N . SER B 1 495 ? -66.601 -15.998 40.657 1.00 74.04 ? 495 SER B N 1 ATOM 8101 C CA . SER B 1 495 ? -67.229 -17.265 40.258 1.00 75.01 ? 495 SER B CA 1 ATOM 8102 C C . SER B 1 495 ? -67.347 -17.388 38.746 1.00 75.07 ? 495 SER B C 1 ATOM 8103 O O . SER B 1 495 ? -67.490 -18.491 38.217 1.00 74.74 ? 495 SER B O 1 ATOM 8104 C CB . SER B 1 495 ? -68.605 -17.436 40.903 1.00 75.20 ? 495 SER B CB 1 ATOM 8105 O OG . SER B 1 495 ? -69.628 -17.033 40.004 1.00 76.73 ? 495 SER B OG 1 ATOM 8106 N N . THR B 1 496 ? -67.289 -16.240 38.073 1.00 75.49 ? 496 THR B N 1 ATOM 8107 C CA . THR B 1 496 ? -67.346 -16.168 36.620 1.00 75.88 ? 496 THR B CA 1 ATOM 8108 C C . THR B 1 496 ? -66.018 -16.579 35.977 1.00 75.85 ? 496 THR B C 1 ATOM 8109 O O . THR B 1 496 ? -65.940 -17.611 35.306 1.00 75.89 ? 496 THR B O 1 ATOM 8110 C CB . THR B 1 496 ? -67.628 -14.738 36.135 1.00 76.19 ? 496 THR B CB 1 ATOM 8111 O OG1 . THR B 1 496 ? -68.022 -13.905 37.234 1.00 77.28 ? 496 THR B OG1 1 ATOM 8112 C CG2 . THR B 1 496 ? -68.694 -14.744 35.050 1.00 75.93 ? 496 THR B CG2 1 ATOM 8113 N N . GLU B 1 497 ? -64.976 -15.770 36.179 1.00 75.42 ? 497 GLU B N 1 ATOM 8114 C CA . GLU B 1 497 ? -63.723 -15.935 35.433 1.00 75.19 ? 497 GLU B CA 1 ATOM 8115 C C . GLU B 1 497 ? -62.775 -16.937 36.071 1.00 73.85 ? 497 GLU B C 1 ATOM 8116 O O . GLU B 1 497 ? -61.953 -17.535 35.386 1.00 73.78 ? 497 GLU B O 1 ATOM 8117 C CB . GLU B 1 497 ? -63.027 -14.581 35.276 1.00 76.05 ? 497 GLU B CB 1 ATOM 8118 C CG . GLU B 1 497 ? -64.001 -13.426 35.005 1.00 79.74 ? 497 GLU B CG 1 ATOM 8119 C CD . GLU B 1 497 ? -63.892 -12.316 36.054 1.00 84.83 ? 497 GLU B CD 1 ATOM 8120 O OE1 . GLU B 1 497 ? -64.928 -11.644 36.328 1.00 86.14 ? 497 GLU B OE1 1 ATOM 8121 O OE2 . GLU B 1 497 ? -62.775 -12.143 36.622 1.00 86.27 ? 497 GLU B OE2 1 ATOM 8122 N N . GLN B 1 498 ? -62.881 -17.092 37.388 1.00 72.50 ? 498 GLN B N 1 ATOM 8123 C CA . GLN B 1 498 ? -62.138 -18.111 38.128 1.00 70.84 ? 498 GLN B CA 1 ATOM 8124 C C . GLN B 1 498 ? -60.645 -18.060 37.937 1.00 69.35 ? 498 GLN B C 1 ATOM 8125 O O . GLN B 1 498 ? -60.037 -19.032 37.483 1.00 68.84 ? 498 GLN B O 1 ATOM 8126 C CB . GLN B 1 498 ? -62.634 -19.490 37.745 1.00 71.36 ? 498 GLN B CB 1 ATOM 8127 C CG . GLN B 1 498 ? -64.028 -19.761 38.251 1.00 72.38 ? 498 GLN B CG 1 ATOM 8128 C CD . GLN B 1 498 ? -64.721 -20.873 37.493 1.00 73.08 ? 498 GLN B CD 1 ATOM 8129 O OE1 . GLN B 1 498 ? -64.075 -21.724 36.865 1.00 73.34 ? 498 GLN B OE1 1 ATOM 8130 N NE2 . GLN B 1 498 ? -66.048 -20.879 37.553 1.00 72.87 ? 498 GLN B NE2 1 ATOM 8131 N N . LYS B 1 499 ? -60.056 -16.930 38.309 1.00 67.77 ? 499 LYS B N 1 ATOM 8132 C CA . LYS B 1 499 ? -58.618 -16.755 38.189 1.00 66.43 ? 499 LYS B CA 1 ATOM 8133 C C . LYS B 1 499 ? -57.913 -17.222 39.446 1.00 65.66 ? 499 LYS B C 1 ATOM 8134 O O . LYS B 1 499 ? -58.441 -17.100 40.563 1.00 65.25 ? 499 LYS B O 1 ATOM 8135 C CB . LYS B 1 499 ? -58.258 -15.294 37.949 1.00 66.36 ? 499 LYS B CB 1 ATOM 8136 C CG . LYS B 1 499 ? -59.179 -14.558 37.015 1.00 65.63 ? 499 LYS B CG 1 ATOM 8137 C CD . LYS B 1 499 ? -58.587 -13.211 36.646 1.00 64.37 ? 499 LYS B CD 1 ATOM 8138 C CE . LYS B 1 499 ? -59.662 -12.257 36.160 1.00 63.96 ? 499 LYS B CE 1 ATOM 8139 N NZ . LYS B 1 499 ? -59.057 -10.947 35.795 1.00 64.06 ? 499 LYS B NZ 1 ATOM 8140 N N . TYR B 1 500 ? -56.706 -17.743 39.255 1.00 64.64 ? 500 TYR B N 1 ATOM 8141 C CA . TYR B 1 500 ? -55.884 -18.202 40.362 1.00 63.73 ? 500 TYR B CA 1 ATOM 8142 C C . TYR B 1 500 ? -54.444 -17.824 40.052 1.00 64.16 ? 500 TYR B C 1 ATOM 8143 O O . TYR B 1 500 ? -54.122 -17.455 38.914 1.00 63.89 ? 500 TYR B O 1 ATOM 8144 C CB . TYR B 1 500 ? -56.031 -19.712 40.571 1.00 62.88 ? 500 TYR B CB 1 ATOM 8145 C CG . TYR B 1 500 ? -55.623 -20.557 39.382 1.00 60.29 ? 500 TYR B CG 1 ATOM 8146 C CD1 . TYR B 1 500 ? -56.463 -20.713 38.287 1.00 57.17 ? 500 TYR B CD1 1 ATOM 8147 C CD2 . TYR B 1 500 ? -54.411 -21.220 39.366 1.00 58.95 ? 500 TYR B CD2 1 ATOM 8148 C CE1 . TYR B 1 500 ? -56.096 -21.494 37.212 1.00 56.16 ? 500 TYR B CE1 1 ATOM 8149 C CE2 . TYR B 1 500 ? -54.037 -21.998 38.288 1.00 57.43 ? 500 TYR B CE2 1 ATOM 8150 C CZ . TYR B 1 500 ? -54.887 -22.127 37.222 1.00 55.97 ? 500 TYR B CZ 1 ATOM 8151 O OH . TYR B 1 500 ? -54.511 -22.896 36.167 1.00 55.25 ? 500 TYR B OH 1 ATOM 8152 N N . LEU B 1 501 ? -53.588 -17.885 41.067 1.00 64.55 ? 501 LEU B N 1 ATOM 8153 C CA . LEU B 1 501 ? -52.197 -17.503 40.909 1.00 65.26 ? 501 LEU B CA 1 ATOM 8154 C C . LEU B 1 501 ? -51.340 -18.750 41.037 1.00 66.05 ? 501 LEU B C 1 ATOM 8155 O O . LEU B 1 501 ? -51.548 -19.569 41.952 1.00 66.24 ? 501 LEU B O 1 ATOM 8156 C CB . LEU B 1 501 ? -51.832 -16.504 41.999 1.00 65.04 ? 501 LEU B CB 1 ATOM 8157 C CG . LEU B 1 501 ? -50.413 -15.944 42.048 1.00 64.86 ? 501 LEU B CG 1 ATOM 8158 C CD1 . LEU B 1 501 ? -50.074 -15.157 40.797 1.00 64.26 ? 501 LEU B CD1 1 ATOM 8159 C CD2 . LEU B 1 501 ? -50.302 -15.051 43.259 1.00 64.97 ? 501 LEU B CD2 1 ATOM 8160 N N . THR B 1 502 ? -50.395 -18.926 40.122 1.00 66.95 ? 502 THR B N 1 ATOM 8161 C CA . THR B 1 502 ? -49.502 -20.078 40.236 1.00 68.32 ? 502 THR B CA 1 ATOM 8162 C C . THR B 1 502 ? -48.303 -19.689 41.111 1.00 69.32 ? 502 THR B C 1 ATOM 8163 O O . THR B 1 502 ? -47.767 -18.595 40.977 1.00 69.74 ? 502 THR B O 1 ATOM 8164 C CB . THR B 1 502 ? -49.014 -20.598 38.857 1.00 68.34 ? 502 THR B CB 1 ATOM 8165 O OG1 . THR B 1 502 ? -48.028 -19.703 38.317 1.00 68.42 ? 502 THR B OG1 1 ATOM 8166 C CG2 . THR B 1 502 ? -50.191 -20.748 37.865 1.00 68.25 ? 502 THR B CG2 1 ATOM 8167 N N . LEU B 1 503 ? -47.900 -20.570 42.023 1.00 70.31 ? 503 LEU B N 1 ATOM 8168 C CA . LEU B 1 503 ? -46.766 -20.298 42.908 1.00 70.99 ? 503 LEU B CA 1 ATOM 8169 C C . LEU B 1 503 ? -45.644 -21.215 42.530 1.00 72.60 ? 503 LEU B C 1 ATOM 8170 O O . LEU B 1 503 ? -45.799 -22.442 42.620 1.00 72.75 ? 503 LEU B O 1 ATOM 8171 C CB . LEU B 1 503 ? -47.125 -20.600 44.353 1.00 70.23 ? 503 LEU B CB 1 ATOM 8172 C CG . LEU B 1 503 ? -48.236 -19.737 44.936 1.00 69.01 ? 503 LEU B CG 1 ATOM 8173 C CD1 . LEU B 1 503 ? -48.362 -19.886 46.430 1.00 66.20 ? 503 LEU B CD1 1 ATOM 8174 C CD2 . LEU B 1 503 ? -47.974 -18.299 44.567 1.00 68.84 ? 503 LEU B CD2 1 ATOM 8175 N N . ASN B 1 504 ? -44.522 -20.629 42.101 1.00 74.65 ? 504 ASN B N 1 ATOM 8176 C CA . ASN B 1 504 ? -43.305 -21.386 41.726 1.00 76.42 ? 504 ASN B CA 1 ATOM 8177 C C . ASN B 1 504 ? -42.072 -20.471 41.698 1.00 77.48 ? 504 ASN B C 1 ATOM 8178 O O . ASN B 1 504 ? -42.200 -19.247 41.804 1.00 77.46 ? 504 ASN B O 1 ATOM 8179 C CB . ASN B 1 504 ? -43.483 -22.068 40.368 1.00 76.28 ? 504 ASN B CB 1 ATOM 8180 C CG . ASN B 1 504 ? -43.627 -21.065 39.254 1.00 77.16 ? 504 ASN B CG 1 ATOM 8181 O OD1 . ASN B 1 504 ? -42.633 -20.545 38.743 1.00 77.29 ? 504 ASN B OD1 1 ATOM 8182 N ND2 . ASN B 1 504 ? -44.870 -20.746 38.898 1.00 78.71 ? 504 ASN B ND2 1 ATOM 8183 N N . THR B 1 505 ? -40.890 -21.070 41.545 1.00 79.06 ? 505 THR B N 1 ATOM 8184 C CA . THR B 1 505 ? -39.629 -20.329 41.590 1.00 80.54 ? 505 THR B CA 1 ATOM 8185 C C . THR B 1 505 ? -39.340 -19.493 40.357 1.00 81.86 ? 505 THR B C 1 ATOM 8186 O O . THR B 1 505 ? -38.624 -18.495 40.454 1.00 82.19 ? 505 THR B O 1 ATOM 8187 C CB . THR B 1 505 ? -38.442 -21.257 41.694 1.00 80.53 ? 505 THR B CB 1 ATOM 8188 O OG1 . THR B 1 505 ? -38.294 -21.956 40.448 1.00 80.39 ? 505 THR B OG1 1 ATOM 8189 C CG2 . THR B 1 505 ? -38.617 -22.222 42.854 1.00 80.17 ? 505 THR B CG2 1 ATOM 8190 N N . GLU B 1 506 ? -39.843 -19.908 39.197 1.00 83.42 ? 506 GLU B N 1 ATOM 8191 C CA . GLU B 1 506 ? -39.659 -19.102 37.986 1.00 85.14 ? 506 GLU B CA 1 ATOM 8192 C C . GLU B 1 506 ? -40.585 -17.883 37.965 1.00 85.34 ? 506 GLU B C 1 ATOM 8193 O O . GLU B 1 506 ? -40.364 -16.906 38.693 1.00 85.61 ? 506 GLU B O 1 ATOM 8194 C CB . GLU B 1 506 ? -39.849 -19.942 36.726 1.00 85.56 ? 506 GLU B CB 1 ATOM 8195 C CG . GLU B 1 506 ? -39.006 -21.219 36.723 1.00 88.85 ? 506 GLU B CG 1 ATOM 8196 C CD . GLU B 1 506 ? -39.854 -22.499 36.814 1.00 93.08 ? 506 GLU B CD 1 ATOM 8197 O OE1 . GLU B 1 506 ? -41.085 -22.419 36.551 1.00 95.56 ? 506 GLU B OE1 1 ATOM 8198 O OE2 . GLU B 1 506 ? -39.290 -23.581 37.132 1.00 93.78 ? 506 GLU B OE2 1 ATOM 8199 N N . SER B 1 507 ? -41.615 -17.926 37.126 1.00 85.60 ? 507 SER B N 1 ATOM 8200 C CA . SER B 1 507 ? -42.592 -16.831 37.108 1.00 85.45 ? 507 SER B CA 1 ATOM 8201 C C . SER B 1 507 ? -43.927 -17.302 37.646 1.00 84.76 ? 507 SER B C 1 ATOM 8202 O O . SER B 1 507 ? -44.435 -18.349 37.250 1.00 84.83 ? 507 SER B O 1 ATOM 8203 C CB . SER B 1 507 ? -42.779 -16.264 35.694 1.00 85.79 ? 507 SER B CB 1 ATOM 8204 O OG . SER B 1 507 ? -43.433 -17.196 34.851 1.00 86.18 ? 507 SER B OG 1 ATOM 8205 N N . THR B 1 508 ? -44.486 -16.529 38.560 1.00 83.77 ? 508 THR B N 1 ATOM 8206 C CA . THR B 1 508 ? -45.843 -16.769 38.988 1.00 82.96 ? 508 THR B CA 1 ATOM 8207 C C . THR B 1 508 ? -46.778 -16.177 37.931 1.00 82.09 ? 508 THR B C 1 ATOM 8208 O O . THR B 1 508 ? -46.623 -15.010 37.561 1.00 82.29 ? 508 THR B O 1 ATOM 8209 C CB . THR B 1 508 ? -46.100 -16.069 40.315 1.00 83.14 ? 508 THR B CB 1 ATOM 8210 O OG1 . THR B 1 508 ? -46.135 -14.651 40.094 1.00 83.32 ? 508 THR B OG1 1 ATOM 8211 C CG2 . THR B 1 508 ? -44.992 -16.433 41.331 1.00 83.34 ? 508 THR B CG2 1 ATOM 8212 N N . ARG B 1 509 ? -47.744 -16.962 37.450 1.00 80.62 ? 509 ARG B N 1 ATOM 8213 C CA . ARG B 1 509 ? -48.687 -16.461 36.456 1.00 79.12 ? 509 ARG B CA 1 ATOM 8214 C C . ARG B 1 509 ? -50.128 -16.445 36.956 1.00 77.66 ? 509 ARG B C 1 ATOM 8215 O O . ARG B 1 509 ? -50.471 -17.133 37.923 1.00 77.59 ? 509 ARG B O 1 ATOM 8216 C CB . ARG B 1 509 ? -48.596 -17.294 35.193 1.00 79.50 ? 509 ARG B CB 1 ATOM 8217 C CG . ARG B 1 509 ? -47.277 -17.206 34.510 1.00 81.40 ? 509 ARG B CG 1 ATOM 8218 C CD . ARG B 1 509 ? -47.284 -18.120 33.301 1.00 86.39 ? 509 ARG B CD 1 ATOM 8219 N NE . ARG B 1 509 ? -45.966 -18.249 32.664 1.00 90.74 ? 509 ARG B NE 1 ATOM 8220 C CZ . ARG B 1 509 ? -45.345 -17.258 32.020 1.00 92.15 ? 509 ARG B CZ 1 ATOM 8221 N NH1 . ARG B 1 509 ? -45.914 -16.057 31.949 1.00 92.90 ? 509 ARG B NH1 1 ATOM 8222 N NH2 . ARG B 1 509 ? -44.156 -17.459 31.456 1.00 92.40 ? 509 ARG B NH2 1 ATOM 8223 N N . ILE B 1 510 ? -50.960 -15.640 36.300 1.00 75.87 ? 510 ILE B N 1 ATOM 8224 C CA . ILE B 1 510 ? -52.395 -15.599 36.568 1.00 74.26 ? 510 ILE B CA 1 ATOM 8225 C C . ILE B 1 510 ? -53.121 -16.434 35.515 1.00 73.41 ? 510 ILE B C 1 ATOM 8226 O O . ILE B 1 510 ? -53.004 -16.169 34.324 1.00 73.23 ? 510 ILE B O 1 ATOM 8227 C CB . ILE B 1 510 ? -52.971 -14.173 36.450 1.00 74.15 ? 510 ILE B CB 1 ATOM 8228 C CG1 . ILE B 1 510 ? -52.309 -13.200 37.418 1.00 73.95 ? 510 ILE B CG1 1 ATOM 8229 C CG2 . ILE B 1 510 ? -54.438 -14.195 36.725 1.00 73.82 ? 510 ILE B CG2 1 ATOM 8230 C CD1 . ILE B 1 510 ? -52.767 -13.384 38.813 1.00 75.28 ? 510 ILE B CD1 1 ATOM 8231 N N . MET B 1 511 ? -53.899 -17.420 35.941 1.00 72.36 ? 511 MET B N 1 ATOM 8232 C CA . MET B 1 511 ? -54.570 -18.288 34.993 1.00 71.32 ? 511 MET B CA 1 ATOM 8233 C C . MET B 1 511 ? -56.024 -18.503 35.349 1.00 70.58 ? 511 MET B C 1 ATOM 8234 O O . MET B 1 511 ? -56.465 -18.118 36.434 1.00 70.64 ? 511 MET B O 1 ATOM 8235 C CB . MET B 1 511 ? -53.828 -19.602 34.918 1.00 71.48 ? 511 MET B CB 1 ATOM 8236 C CG . MET B 1 511 ? -52.381 -19.383 34.566 1.00 72.55 ? 511 MET B CG 1 ATOM 8237 S SD . MET B 1 511 ? -51.831 -20.587 33.360 1.00 75.24 ? 511 MET B SD 1 ATOM 8238 C CE . MET B 1 511 ? -51.408 -21.966 34.433 1.00 74.74 ? 511 MET B CE 1 ATOM 8239 N N . THR B 1 512 ? -56.780 -19.102 34.439 1.00 69.49 ? 512 THR B N 1 ATOM 8240 C CA . THR B 1 512 ? -58.201 -19.272 34.677 1.00 68.68 ? 512 THR B CA 1 ATOM 8241 C C . THR B 1 512 ? -58.650 -20.720 34.683 1.00 68.22 ? 512 THR B C 1 ATOM 8242 O O . THR B 1 512 ? -58.066 -21.581 34.039 1.00 67.66 ? 512 THR B O 1 ATOM 8243 C CB . THR B 1 512 ? -59.034 -18.547 33.628 1.00 68.65 ? 512 THR B CB 1 ATOM 8244 O OG1 . THR B 1 512 ? -58.529 -18.875 32.335 1.00 69.30 ? 512 THR B OG1 1 ATOM 8245 C CG2 . THR B 1 512 ? -58.936 -17.079 33.815 1.00 68.22 ? 512 THR B CG2 1 ATOM 8246 N N . LYS B 1 513 ? -59.702 -20.978 35.443 1.00 68.03 ? 513 LYS B N 1 ATOM 8247 C CA . LYS B 1 513 ? -60.435 -22.211 35.300 1.00 67.94 ? 513 LYS B CA 1 ATOM 8248 C C . LYS B 1 513 ? -59.579 -23.443 35.484 1.00 67.56 ? 513 LYS B C 1 ATOM 8249 O O . LYS B 1 513 ? -59.543 -24.314 34.637 1.00 67.29 ? 513 LYS B O 1 ATOM 8250 C CB . LYS B 1 513 ? -61.123 -22.224 33.933 1.00 68.39 ? 513 LYS B CB 1 ATOM 8251 C CG . LYS B 1 513 ? -62.377 -21.334 33.907 1.00 69.39 ? 513 LYS B CG 1 ATOM 8252 C CD . LYS B 1 513 ? -62.733 -20.801 32.528 1.00 70.47 ? 513 LYS B CD 1 ATOM 8253 C CE . LYS B 1 513 ? -63.743 -19.675 32.671 1.00 71.35 ? 513 LYS B CE 1 ATOM 8254 N NZ . LYS B 1 513 ? -64.674 -19.594 31.525 1.00 72.68 ? 513 LYS B NZ 1 ATOM 8255 N N . LEU B 1 514 ? -58.907 -23.514 36.625 1.00 67.74 ? 514 LEU B N 1 ATOM 8256 C CA . LEU B 1 514 ? -58.098 -24.680 36.981 1.00 67.62 ? 514 LEU B CA 1 ATOM 8257 C C . LEU B 1 514 ? -58.859 -25.978 36.712 1.00 68.06 ? 514 LEU B C 1 ATOM 8258 O O . LEU B 1 514 ? -60.005 -26.134 37.126 1.00 68.18 ? 514 LEU B O 1 ATOM 8259 C CB . LEU B 1 514 ? -57.697 -24.619 38.459 1.00 67.01 ? 514 LEU B CB 1 ATOM 8260 C CG . LEU B 1 514 ? -56.687 -25.668 38.918 1.00 65.40 ? 514 LEU B CG 1 ATOM 8261 C CD1 . LEU B 1 514 ? -55.353 -25.470 38.259 1.00 63.90 ? 514 LEU B CD1 1 ATOM 8262 C CD2 . LEU B 1 514 ? -56.517 -25.589 40.397 1.00 64.17 ? 514 LEU B CD2 1 ATOM 8263 N N . ARG B 1 515 ? -58.226 -26.906 36.009 1.00 68.38 ? 515 ARG B N 1 ATOM 8264 C CA . ARG B 1 515 ? -58.840 -28.201 35.806 1.00 69.02 ? 515 ARG B CA 1 ATOM 8265 C C . ARG B 1 515 ? -60.347 -28.125 35.597 1.00 69.25 ? 515 ARG B C 1 ATOM 8266 O O . ARG B 1 515 ? -61.111 -28.789 36.308 1.00 68.97 ? 515 ARG B O 1 ATOM 8267 C CB . ARG B 1 515 ? -58.570 -29.054 37.015 1.00 69.22 ? 515 ARG B CB 1 ATOM 8268 C CG . ARG B 1 515 ? -57.117 -29.282 37.217 1.00 70.84 ? 515 ARG B CG 1 ATOM 8269 C CD . ARG B 1 515 ? -56.704 -30.537 36.545 1.00 73.72 ? 515 ARG B CD 1 ATOM 8270 N NE . ARG B 1 515 ? -56.062 -31.347 37.551 1.00 76.49 ? 515 ARG B NE 1 ATOM 8271 C CZ . ARG B 1 515 ? -54.904 -31.021 38.110 1.00 79.13 ? 515 ARG B CZ 1 ATOM 8272 N NH1 . ARG B 1 515 ? -54.366 -31.806 39.051 1.00 80.31 ? 515 ARG B NH1 1 ATOM 8273 N NH2 . ARG B 1 515 ? -54.279 -29.913 37.711 1.00 79.14 ? 515 ARG B NH2 1 ATOM 8274 N N . ALA B 1 516 ? -60.764 -27.339 34.604 1.00 69.75 ? 516 ALA B N 1 ATOM 8275 C CA . ALA B 1 516 ? -62.179 -27.151 34.302 1.00 69.95 ? 516 ALA B CA 1 ATOM 8276 C C . ALA B 1 516 ? -62.777 -28.432 33.765 1.00 70.30 ? 516 ALA B C 1 ATOM 8277 O O . ALA B 1 516 ? -63.811 -28.900 34.249 1.00 70.47 ? 516 ALA B O 1 ATOM 8278 C CB . ALA B 1 516 ? -62.358 -26.038 33.307 1.00 69.78 ? 516 ALA B CB 1 ATOM 8279 N N . GLN B 1 517 ? -62.110 -28.991 32.760 1.00 70.73 ? 517 GLN B N 1 ATOM 8280 C CA . GLN B 1 517 ? -62.519 -30.244 32.132 1.00 71.31 ? 517 GLN B CA 1 ATOM 8281 C C . GLN B 1 517 ? -62.872 -31.318 33.180 1.00 70.52 ? 517 GLN B C 1 ATOM 8282 O O . GLN B 1 517 ? -64.004 -31.807 33.236 1.00 70.31 ? 517 GLN B O 1 ATOM 8283 C CB . GLN B 1 517 ? -61.384 -30.743 31.215 1.00 72.11 ? 517 GLN B CB 1 ATOM 8284 C CG . GLN B 1 517 ? -61.720 -31.988 30.413 1.00 75.74 ? 517 GLN B CG 1 ATOM 8285 C CD . GLN B 1 517 ? -62.615 -31.659 29.223 1.00 81.15 ? 517 GLN B CD 1 ATOM 8286 O OE1 . GLN B 1 517 ? -62.120 -31.240 28.170 1.00 83.41 ? 517 GLN B OE1 1 ATOM 8287 N NE2 . GLN B 1 517 ? -63.940 -31.836 29.384 1.00 82.40 ? 517 GLN B NE2 1 ATOM 8288 N N . GLN B 1 518 ? -61.886 -31.640 34.021 1.00 69.73 ? 518 GLN B N 1 ATOM 8289 C CA . GLN B 1 518 ? -61.949 -32.737 34.978 1.00 68.49 ? 518 GLN B CA 1 ATOM 8290 C C . GLN B 1 518 ? -62.942 -32.466 36.073 1.00 68.00 ? 518 GLN B C 1 ATOM 8291 O O . GLN B 1 518 ? -63.733 -33.319 36.429 1.00 67.89 ? 518 GLN B O 1 ATOM 8292 C CB . GLN B 1 518 ? -60.582 -32.973 35.603 1.00 68.23 ? 518 GLN B CB 1 ATOM 8293 C CG . GLN B 1 518 ? -59.494 -33.296 34.616 1.00 68.55 ? 518 GLN B CG 1 ATOM 8294 C CD . GLN B 1 518 ? -58.817 -32.055 34.035 1.00 69.61 ? 518 GLN B CD 1 ATOM 8295 O OE1 . GLN B 1 518 ? -57.639 -32.091 33.692 1.00 70.64 ? 518 GLN B OE1 1 ATOM 8296 N NE2 . GLN B 1 518 ? -59.554 -30.952 33.928 1.00 69.73 ? 518 GLN B NE2 1 ATOM 8297 N N . CYS B 1 519 ? -62.926 -31.271 36.616 1.00 67.54 ? 519 CYS B N 1 ATOM 8298 C CA . CYS B 1 519 ? -63.825 -31.041 37.718 1.00 67.53 ? 519 CYS B CA 1 ATOM 8299 C C . CYS B 1 519 ? -65.285 -31.007 37.301 1.00 67.76 ? 519 CYS B C 1 ATOM 8300 O O . CYS B 1 519 ? -66.172 -31.139 38.138 1.00 67.57 ? 519 CYS B O 1 ATOM 8301 C CB . CYS B 1 519 ? -63.448 -29.781 38.489 1.00 67.38 ? 519 CYS B CB 1 ATOM 8302 S SG . CYS B 1 519 ? -61.901 -29.938 39.440 1.00 66.94 ? 519 CYS B SG 1 ATOM 8303 N N . ARG B 1 520 ? -65.547 -30.825 36.014 1.00 68.24 ? 520 ARG B N 1 ATOM 8304 C CA . ARG B 1 520 ? -66.922 -30.881 35.555 1.00 68.80 ? 520 ARG B CA 1 ATOM 8305 C C . ARG B 1 520 ? -67.410 -32.282 35.848 1.00 68.29 ? 520 ARG B C 1 ATOM 8306 O O . ARG B 1 520 ? -68.468 -32.487 36.440 1.00 67.97 ? 520 ARG B O 1 ATOM 8307 C CB . ARG B 1 520 ? -67.008 -30.594 34.060 1.00 69.24 ? 520 ARG B CB 1 ATOM 8308 C CG . ARG B 1 520 ? -68.418 -30.280 33.555 1.00 72.13 ? 520 ARG B CG 1 ATOM 8309 C CD . ARG B 1 520 ? -68.384 -29.493 32.238 1.00 77.49 ? 520 ARG B CD 1 ATOM 8310 N NE . ARG B 1 520 ? -67.704 -28.204 32.382 1.00 81.54 ? 520 ARG B NE 1 ATOM 8311 C CZ . ARG B 1 520 ? -66.537 -27.895 31.816 1.00 84.20 ? 520 ARG B CZ 1 ATOM 8312 N NH1 . ARG B 1 520 ? -65.998 -26.695 32.021 1.00 85.32 ? 520 ARG B NH1 1 ATOM 8313 N NH2 . ARG B 1 520 ? -65.907 -28.778 31.037 1.00 85.53 ? 520 ARG B NH2 1 ATOM 8314 N N . PHE B 1 521 ? -66.588 -33.239 35.445 1.00 68.12 ? 521 PHE B N 1 ATOM 8315 C CA . PHE B 1 521 ? -66.842 -34.646 35.658 1.00 67.97 ? 521 PHE B CA 1 ATOM 8316 C C . PHE B 1 521 ? -67.083 -34.978 37.122 1.00 68.01 ? 521 PHE B C 1 ATOM 8317 O O . PHE B 1 521 ? -68.092 -35.570 37.462 1.00 67.65 ? 521 PHE B O 1 ATOM 8318 C CB . PHE B 1 521 ? -65.655 -35.444 35.140 1.00 67.88 ? 521 PHE B CB 1 ATOM 8319 C CG . PHE B 1 521 ? -65.715 -36.874 35.493 1.00 68.03 ? 521 PHE B CG 1 ATOM 8320 C CD1 . PHE B 1 521 ? -66.250 -37.783 34.616 1.00 67.97 ? 521 PHE B CD1 1 ATOM 8321 C CD2 . PHE B 1 521 ? -65.265 -37.310 36.728 1.00 68.81 ? 521 PHE B CD2 1 ATOM 8322 C CE1 . PHE B 1 521 ? -66.323 -39.097 34.953 1.00 68.87 ? 521 PHE B CE1 1 ATOM 8323 C CE2 . PHE B 1 521 ? -65.322 -38.633 37.082 1.00 68.46 ? 521 PHE B CE2 1 ATOM 8324 C CZ . PHE B 1 521 ? -65.857 -39.531 36.200 1.00 69.47 ? 521 PHE B CZ 1 ATOM 8325 N N . TRP B 1 522 ? -66.147 -34.580 37.981 1.00 68.52 ? 522 TRP B N 1 ATOM 8326 C CA . TRP B 1 522 ? -66.235 -34.850 39.415 1.00 68.91 ? 522 TRP B CA 1 ATOM 8327 C C . TRP B 1 522 ? -67.384 -34.123 40.087 1.00 69.87 ? 522 TRP B C 1 ATOM 8328 O O . TRP B 1 522 ? -68.057 -34.679 40.945 1.00 69.84 ? 522 TRP B O 1 ATOM 8329 C CB . TRP B 1 522 ? -64.923 -34.510 40.105 1.00 68.40 ? 522 TRP B CB 1 ATOM 8330 C CG . TRP B 1 522 ? -63.847 -35.398 39.669 1.00 67.80 ? 522 TRP B CG 1 ATOM 8331 C CD1 . TRP B 1 522 ? -62.787 -35.082 38.865 1.00 67.30 ? 522 TRP B CD1 1 ATOM 8332 C CD2 . TRP B 1 522 ? -63.725 -36.790 39.971 1.00 67.64 ? 522 TRP B CD2 1 ATOM 8333 N NE1 . TRP B 1 522 ? -62.002 -36.194 38.661 1.00 66.46 ? 522 TRP B NE1 1 ATOM 8334 C CE2 . TRP B 1 522 ? -62.560 -37.258 39.327 1.00 67.32 ? 522 TRP B CE2 1 ATOM 8335 C CE3 . TRP B 1 522 ? -64.484 -37.688 40.733 1.00 67.40 ? 522 TRP B CE3 1 ATOM 8336 C CZ2 . TRP B 1 522 ? -62.138 -38.580 39.422 1.00 67.52 ? 522 TRP B CZ2 1 ATOM 8337 C CZ3 . TRP B 1 522 ? -64.063 -39.002 40.826 1.00 67.26 ? 522 TRP B CZ3 1 ATOM 8338 C CH2 . TRP B 1 522 ? -62.900 -39.435 40.175 1.00 67.83 ? 522 TRP B CH2 1 ATOM 8339 N N . THR B 1 523 ? -67.624 -32.886 39.679 1.00 71.29 ? 523 THR B N 1 ATOM 8340 C CA . THR B 1 523 ? -68.675 -32.086 40.293 1.00 72.86 ? 523 THR B CA 1 ATOM 8341 C C . THR B 1 523 ? -70.084 -32.326 39.736 1.00 73.46 ? 523 THR B C 1 ATOM 8342 O O . THR B 1 523 ? -71.063 -32.335 40.478 1.00 73.40 ? 523 THR B O 1 ATOM 8343 C CB . THR B 1 523 ? -68.341 -30.591 40.222 1.00 72.85 ? 523 THR B CB 1 ATOM 8344 O OG1 . THR B 1 523 ? -67.157 -30.357 40.991 1.00 73.95 ? 523 THR B OG1 1 ATOM 8345 C CG2 . THR B 1 523 ? -69.496 -29.749 40.788 1.00 73.10 ? 523 THR B CG2 1 ATOM 8346 N N . SER B 1 524 ? -70.195 -32.523 38.435 1.00 74.47 ? 524 SER B N 1 ATOM 8347 C CA . SER B 1 524 ? -71.513 -32.594 37.845 1.00 75.60 ? 524 SER B CA 1 ATOM 8348 C C . SER B 1 524 ? -71.958 -34.008 37.666 1.00 76.36 ? 524 SER B C 1 ATOM 8349 O O . SER B 1 524 ? -73.075 -34.357 38.030 1.00 76.99 ? 524 SER B O 1 ATOM 8350 C CB . SER B 1 524 ? -71.526 -31.893 36.502 1.00 75.58 ? 524 SER B CB 1 ATOM 8351 O OG . SER B 1 524 ? -71.363 -30.502 36.708 1.00 76.52 ? 524 SER B OG 1 ATOM 8352 N N . PHE B 1 525 ? -71.075 -34.826 37.112 1.00 77.00 ? 525 PHE B N 1 ATOM 8353 C CA . PHE B 1 525 ? -71.418 -36.202 36.815 1.00 77.73 ? 525 PHE B CA 1 ATOM 8354 C C . PHE B 1 525 ? -71.301 -37.196 37.991 1.00 77.73 ? 525 PHE B C 1 ATOM 8355 O O . PHE B 1 525 ? -72.285 -37.835 38.371 1.00 77.84 ? 525 PHE B O 1 ATOM 8356 C CB . PHE B 1 525 ? -70.603 -36.688 35.627 1.00 77.98 ? 525 PHE B CB 1 ATOM 8357 C CG . PHE B 1 525 ? -70.897 -38.089 35.255 1.00 80.46 ? 525 PHE B CG 1 ATOM 8358 C CD1 . PHE B 1 525 ? -69.928 -38.883 34.683 1.00 82.88 ? 525 PHE B CD1 1 ATOM 8359 C CD2 . PHE B 1 525 ? -72.160 -38.626 35.488 1.00 82.91 ? 525 PHE B CD2 1 ATOM 8360 C CE1 . PHE B 1 525 ? -70.211 -40.185 34.331 1.00 84.65 ? 525 PHE B CE1 1 ATOM 8361 C CE2 . PHE B 1 525 ? -72.451 -39.924 35.158 1.00 84.64 ? 525 PHE B CE2 1 ATOM 8362 C CZ . PHE B 1 525 ? -71.470 -40.712 34.581 1.00 85.63 ? 525 PHE B CZ 1 ATOM 8363 N N . PHE B 1 526 ? -70.109 -37.306 38.571 1.00 77.75 ? 526 PHE B N 1 ATOM 8364 C CA . PHE B 1 526 ? -69.786 -38.418 39.459 1.00 77.59 ? 526 PHE B CA 1 ATOM 8365 C C . PHE B 1 526 ? -70.656 -38.590 40.708 1.00 78.36 ? 526 PHE B C 1 ATOM 8366 O O . PHE B 1 526 ? -70.856 -39.714 41.179 1.00 78.63 ? 526 PHE B O 1 ATOM 8367 C CB . PHE B 1 526 ? -68.313 -38.394 39.842 1.00 77.04 ? 526 PHE B CB 1 ATOM 8368 C CG . PHE B 1 526 ? -67.822 -39.686 40.425 1.00 75.45 ? 526 PHE B CG 1 ATOM 8369 C CD1 . PHE B 1 526 ? -67.458 -40.748 39.608 1.00 74.05 ? 526 PHE B CD1 1 ATOM 8370 C CD2 . PHE B 1 526 ? -67.730 -39.845 41.792 1.00 74.16 ? 526 PHE B CD2 1 ATOM 8371 C CE1 . PHE B 1 526 ? -67.002 -41.941 40.148 1.00 72.56 ? 526 PHE B CE1 1 ATOM 8372 C CE2 . PHE B 1 526 ? -67.279 -41.027 42.338 1.00 73.19 ? 526 PHE B CE2 1 ATOM 8373 C CZ . PHE B 1 526 ? -66.912 -42.077 41.511 1.00 72.78 ? 526 PHE B CZ 1 ATOM 8374 N N . PRO B 1 527 ? -71.178 -37.489 41.265 1.00 78.88 ? 527 PRO B N 1 ATOM 8375 C CA . PRO B 1 527 ? -71.966 -37.691 42.487 1.00 79.14 ? 527 PRO B CA 1 ATOM 8376 C C . PRO B 1 527 ? -73.211 -38.483 42.189 1.00 79.76 ? 527 PRO B C 1 ATOM 8377 O O . PRO B 1 527 ? -73.915 -38.899 43.094 1.00 79.96 ? 527 PRO B O 1 ATOM 8378 C CB . PRO B 1 527 ? -72.357 -36.274 42.896 1.00 78.82 ? 527 PRO B CB 1 ATOM 8379 C CG . PRO B 1 527 ? -71.324 -35.406 42.272 1.00 79.19 ? 527 PRO B CG 1 ATOM 8380 C CD . PRO B 1 527 ? -70.964 -36.066 40.966 1.00 78.83 ? 527 PRO B CD 1 ATOM 8381 N N . LYS B 1 528 ? -73.481 -38.691 40.911 1.00 80.61 ? 528 LYS B N 1 ATOM 8382 C CA . LYS B 1 528 ? -74.697 -39.355 40.509 1.00 81.34 ? 528 LYS B CA 1 ATOM 8383 C C . LYS B 1 528 ? -74.533 -40.868 40.347 1.00 81.81 ? 528 LYS B C 1 ATOM 8384 O O . LYS B 1 528 ? -75.479 -41.621 40.585 1.00 82.15 ? 528 LYS B O 1 ATOM 8385 C CB . LYS B 1 528 ? -75.254 -38.686 39.258 1.00 81.29 ? 528 LYS B CB 1 ATOM 8386 C CG . LYS B 1 528 ? -75.842 -37.330 39.591 1.00 81.79 ? 528 LYS B CG 1 ATOM 8387 C CD . LYS B 1 528 ? -75.595 -36.297 38.505 1.00 82.43 ? 528 LYS B CD 1 ATOM 8388 C CE . LYS B 1 528 ? -76.527 -36.472 37.315 1.00 82.79 ? 528 LYS B CE 1 ATOM 8389 N NZ . LYS B 1 528 ? -76.220 -35.458 36.259 1.00 82.57 ? 528 LYS B NZ 1 ATOM 8390 N N . VAL B 1 529 ? -73.339 -41.323 39.979 1.00 82.05 ? 529 VAL B N 1 ATOM 8391 C CA . VAL B 1 529 ? -73.108 -42.763 39.861 1.00 82.38 ? 529 VAL B CA 1 ATOM 8392 C C . VAL B 1 529 ? -73.196 -43.480 41.223 1.00 82.73 ? 529 VAL B C 1 ATOM 8393 O O . VAL B 1 529 ? -73.414 -42.877 42.285 1.00 82.71 ? 529 VAL B O 1 ATOM 8394 C CB . VAL B 1 529 ? -71.752 -43.086 39.198 1.00 82.34 ? 529 VAL B CB 1 ATOM 8395 C CG1 . VAL B 1 529 ? -71.539 -42.233 37.943 1.00 82.30 ? 529 VAL B CG1 1 ATOM 8396 C CG2 . VAL B 1 529 ? -70.628 -42.873 40.181 1.00 82.40 ? 529 VAL B CG2 1 ATOM 8397 O OXT . VAL B 1 529 ? -73.057 -44.704 41.298 1.00 83.09 ? 529 VAL B OXT 1 HETATM 8398 C C4 . TCX C 2 . ? -34.517 -9.619 10.095 1.00 54.72 ? 601 TCX A C4 1 HETATM 8399 C C3 . TCX C 2 . ? -35.939 -10.058 9.768 1.00 54.51 ? 601 TCX A C3 1 HETATM 8400 N N . TCX C 2 . ? -35.975 -11.462 10.125 1.00 54.58 ? 601 TCX A N 1 HETATM 8401 P P . TCX C 2 . ? -36.751 -12.448 9.051 1.00 54.58 ? 601 TCX A P 1 HETATM 8402 O O3 . TCX C 2 . ? -35.860 -13.817 9.000 1.00 54.31 ? 601 TCX A O3 1 HETATM 8403 O O2 . TCX C 2 . ? -37.135 -11.979 7.703 1.00 53.39 ? 601 TCX A O2 1 HETATM 8404 C C1 . NAG D 3 . ? -23.598 7.126 5.159 1.00 109.35 ? 602 NAG A C1 1 HETATM 8405 C C2 . NAG D 3 . ? -23.557 7.267 6.682 1.00 114.22 ? 602 NAG A C2 1 HETATM 8406 C C3 . NAG D 3 . ? -22.179 7.305 7.370 1.00 115.46 ? 602 NAG A C3 1 HETATM 8407 C C4 . NAG D 3 . ? -20.947 6.971 6.523 1.00 117.03 ? 602 NAG A C4 1 HETATM 8408 C C5 . NAG D 3 . ? -21.193 7.226 5.037 1.00 115.16 ? 602 NAG A C5 1 HETATM 8409 C C6 . NAG D 3 . ? -20.047 6.614 4.235 1.00 115.60 ? 602 NAG A C6 1 HETATM 8410 C C7 . NAG D 3 . ? -25.243 8.409 7.988 1.00 116.80 ? 602 NAG A C7 1 HETATM 8411 C C8 . NAG D 3 . ? -25.239 9.498 9.034 1.00 116.53 ? 602 NAG A C8 1 HETATM 8412 N N2 . NAG D 3 . ? -24.294 8.461 7.061 1.00 115.60 ? 602 NAG A N2 1 HETATM 8413 O O3 . NAG D 3 . ? -22.214 6.397 8.449 1.00 115.49 ? 602 NAG A O3 1 HETATM 8414 O O4 . NAG D 3 . ? -19.778 7.635 7.031 1.00 121.04 ? 602 NAG A O4 1 HETATM 8415 O O5 . NAG D 3 . ? -22.397 6.600 4.626 1.00 112.13 ? 602 NAG A O5 1 HETATM 8416 O O6 . NAG D 3 . ? -19.975 5.212 4.469 1.00 116.39 ? 602 NAG A O6 1 HETATM 8417 O O7 . NAG D 3 . ? -26.073 7.497 7.988 1.00 117.23 ? 602 NAG A O7 1 HETATM 8418 C C1 . NAG E 3 . ? -18.893 6.648 7.653 1.00 124.79 ? 603 NAG A C1 1 HETATM 8419 C C2 . NAG E 3 . ? -17.420 7.065 7.706 1.00 126.06 ? 603 NAG A C2 1 HETATM 8420 C C3 . NAG E 3 . ? -16.720 6.420 8.894 1.00 127.05 ? 603 NAG A C3 1 HETATM 8421 C C4 . NAG E 3 . ? -17.375 6.888 10.181 1.00 127.57 ? 603 NAG A C4 1 HETATM 8422 C C5 . NAG E 3 . ? -18.899 6.742 10.109 1.00 126.99 ? 603 NAG A C5 1 HETATM 8423 C C6 . NAG E 3 . ? -19.600 8.087 10.287 1.00 126.94 ? 603 NAG A C6 1 HETATM 8424 C C7 . NAG E 3 . ? -15.954 7.424 5.840 1.00 127.91 ? 603 NAG A C7 1 HETATM 8425 C C8 . NAG E 3 . ? -14.539 6.967 5.589 1.00 127.76 ? 603 NAG A C8 1 HETATM 8426 N N2 . NAG E 3 . ? -16.740 6.603 6.519 1.00 127.09 ? 603 NAG A N2 1 HETATM 8427 O O3 . NAG E 3 . ? -15.337 6.726 8.926 1.00 126.92 ? 603 NAG A O3 1 HETATM 8428 O O4 . NAG E 3 . ? -16.828 6.160 11.264 1.00 128.33 ? 603 NAG A O4 1 HETATM 8429 O O5 . NAG E 3 . ? -19.331 6.117 8.906 1.00 126.27 ? 603 NAG A O5 1 HETATM 8430 O O6 . NAG E 3 . ? -20.583 7.952 11.286 1.00 126.67 ? 603 NAG A O6 1 HETATM 8431 O O7 . NAG E 3 . ? -16.371 8.511 5.444 1.00 128.09 ? 603 NAG A O7 1 HETATM 8432 C C1 . FUC F 4 . ? -18.648 4.699 4.147 1.00 116.74 ? 604 FUC A C1 1 HETATM 8433 C C2 . FUC F 4 . ? -18.281 3.414 4.912 1.00 116.33 ? 604 FUC A C2 1 HETATM 8434 C C3 . FUC F 4 . ? -19.044 2.213 4.349 1.00 116.25 ? 604 FUC A C3 1 HETATM 8435 C C4 . FUC F 4 . ? -19.007 2.171 2.814 1.00 116.56 ? 604 FUC A C4 1 HETATM 8436 C C5 . FUC F 4 . ? -19.254 3.532 2.165 1.00 116.43 ? 604 FUC A C5 1 HETATM 8437 C C6 . FUC F 4 . ? -18.983 3.493 0.666 1.00 115.87 ? 604 FUC A C6 1 HETATM 8438 O O2 . FUC F 4 . ? -18.478 3.537 6.316 1.00 115.67 ? 604 FUC A O2 1 HETATM 8439 O O3 . FUC F 4 . ? -18.505 1.021 4.880 1.00 115.49 ? 604 FUC A O3 1 HETATM 8440 O O4 . FUC F 4 . ? -17.762 1.679 2.368 1.00 117.36 ? 604 FUC A O4 1 HETATM 8441 O O5 . FUC F 4 . ? -18.417 4.504 2.755 1.00 116.86 ? 604 FUC A O5 1 HETATM 8442 C C1 . NAG G 3 . ? -17.908 -21.818 23.103 1.00 92.21 ? 605 NAG A C1 1 HETATM 8443 C C2 . NAG G 3 . ? -16.740 -21.309 23.939 1.00 95.11 ? 605 NAG A C2 1 HETATM 8444 C C3 . NAG G 3 . ? -16.160 -20.017 23.381 1.00 96.44 ? 605 NAG A C3 1 HETATM 8445 C C4 . NAG G 3 . ? -15.878 -20.121 21.890 1.00 98.37 ? 605 NAG A C4 1 HETATM 8446 C C5 . NAG G 3 . ? -17.138 -20.646 21.208 1.00 97.78 ? 605 NAG A C5 1 HETATM 8447 C C6 . NAG G 3 . ? -16.979 -20.819 19.700 1.00 100.34 ? 605 NAG A C6 1 HETATM 8448 C C7 . NAG G 3 . ? -17.198 -21.963 26.243 1.00 96.80 ? 605 NAG A C7 1 HETATM 8449 C C8 . NAG G 3 . ? -16.490 -21.637 27.533 1.00 96.45 ? 605 NAG A C8 1 HETATM 8450 N N2 . NAG G 3 . ? -17.175 -21.036 25.289 1.00 95.87 ? 605 NAG A N2 1 HETATM 8451 O O3 . NAG G 3 . ? -14.993 -19.703 24.099 1.00 95.55 ? 605 NAG A O3 1 HETATM 8452 O O4 . NAG G 3 . ? -15.545 -18.848 21.373 1.00 102.23 ? 605 NAG A O4 1 HETATM 8453 O O5 . NAG G 3 . ? -17.506 -21.887 21.760 1.00 94.24 ? 605 NAG A O5 1 HETATM 8454 O O6 . NAG G 3 . ? -15.707 -21.353 19.408 1.00 104.19 ? 605 NAG A O6 1 HETATM 8455 O O7 . NAG G 3 . ? -17.776 -23.041 26.095 1.00 96.93 ? 605 NAG A O7 1 HETATM 8456 C C1 . NAG H 3 . ? -14.115 -18.675 21.241 1.00 106.76 ? 606 NAG A C1 1 HETATM 8457 C C2 . NAG H 3 . ? -13.774 -17.569 20.249 1.00 108.64 ? 606 NAG A C2 1 HETATM 8458 C C3 . NAG H 3 . ? -12.279 -17.671 19.958 1.00 109.79 ? 606 NAG A C3 1 HETATM 8459 C C4 . NAG H 3 . ? -11.565 -17.251 21.233 1.00 110.16 ? 606 NAG A C4 1 HETATM 8460 C C5 . NAG H 3 . ? -12.099 -17.935 22.492 1.00 110.04 ? 606 NAG A C5 1 HETATM 8461 C C6 . NAG H 3 . ? -11.871 -16.944 23.635 1.00 111.06 ? 606 NAG A C6 1 HETATM 8462 C C7 . NAG H 3 . ? -15.477 -16.664 18.802 1.00 109.19 ? 606 NAG A C7 1 HETATM 8463 C C8 . NAG H 3 . ? -15.450 -16.022 17.433 1.00 108.84 ? 606 NAG A C8 1 HETATM 8464 N N2 . NAG H 3 . ? -14.582 -17.619 19.045 1.00 109.22 ? 606 NAG A N2 1 HETATM 8465 O O3 . NAG H 3 . ? -11.870 -16.828 18.902 1.00 109.95 ? 606 NAG A O3 1 HETATM 8466 O O4 . NAG H 3 . ? -10.172 -17.471 21.148 1.00 110.22 ? 606 NAG A O4 1 HETATM 8467 O O5 . NAG H 3 . ? -13.469 -18.381 22.471 1.00 108.73 ? 606 NAG A O5 1 HETATM 8468 O O6 . NAG H 3 . ? -12.406 -17.423 24.851 1.00 112.37 ? 606 NAG A O6 1 HETATM 8469 O O7 . NAG H 3 . ? -16.288 -16.323 19.668 1.00 108.28 ? 606 NAG A O7 1 HETATM 8470 C C1 . FUC I 4 . ? -15.746 -22.396 18.405 1.00 106.32 ? 607 FUC A C1 1 HETATM 8471 C C2 . FUC I 4 . ? -14.309 -22.813 18.176 1.00 107.07 ? 607 FUC A C2 1 HETATM 8472 C C3 . FUC I 4 . ? -13.791 -23.276 19.525 1.00 108.00 ? 607 FUC A C3 1 HETATM 8473 C C4 . FUC I 4 . ? -14.571 -24.502 19.982 1.00 108.47 ? 607 FUC A C4 1 HETATM 8474 C C5 . FUC I 4 . ? -16.080 -24.264 19.913 1.00 108.14 ? 607 FUC A C5 1 HETATM 8475 C C6 . FUC I 4 . ? -16.828 -25.593 19.999 1.00 107.75 ? 607 FUC A C6 1 HETATM 8476 O O2 . FUC I 4 . ? -13.555 -21.707 17.746 1.00 107.10 ? 607 FUC A O2 1 HETATM 8477 O O3 . FUC I 4 . ? -12.414 -23.563 19.449 1.00 108.55 ? 607 FUC A O3 1 HETATM 8478 O O4 . FUC I 4 . ? -14.221 -25.612 19.184 1.00 108.98 ? 607 FUC A O4 1 HETATM 8479 O O5 . FUC I 4 . ? -16.483 -23.558 18.740 1.00 107.46 ? 607 FUC A O5 1 HETATM 8480 C C1 . NAG J 3 . ? -67.683 -18.520 -5.261 1.00 92.82 ? 608 NAG A C1 1 HETATM 8481 C C2 . NAG J 3 . ? -68.694 -18.127 -6.360 1.00 94.99 ? 608 NAG A C2 1 HETATM 8482 C C3 . NAG J 3 . ? -68.943 -16.626 -6.337 1.00 95.62 ? 608 NAG A C3 1 HETATM 8483 C C4 . NAG J 3 . ? -69.506 -16.300 -4.958 1.00 95.87 ? 608 NAG A C4 1 HETATM 8484 C C5 . NAG J 3 . ? -68.443 -16.627 -3.902 1.00 95.53 ? 608 NAG A C5 1 HETATM 8485 C C6 . NAG J 3 . ? -68.910 -16.311 -2.468 1.00 95.02 ? 608 NAG A C6 1 HETATM 8486 C C7 . NAG J 3 . ? -68.750 -19.815 -8.035 1.00 92.87 ? 608 NAG A C7 1 HETATM 8487 C C8 . NAG J 3 . ? -70.226 -19.990 -8.224 1.00 92.53 ? 608 NAG A C8 1 HETATM 8488 N N2 . NAG J 3 . ? -68.338 -18.603 -7.694 1.00 93.67 ? 608 NAG A N2 1 HETATM 8489 O O3 . NAG J 3 . ? -69.837 -16.267 -7.371 1.00 95.93 ? 608 NAG A O3 1 HETATM 8490 O O4 . NAG J 3 . ? -69.917 -14.950 -4.910 1.00 96.50 ? 608 NAG A O4 1 HETATM 8491 O O5 . NAG J 3 . ? -68.102 -18.006 -3.994 1.00 94.51 ? 608 NAG A O5 1 HETATM 8492 O O6 . NAG J 3 . ? -67.888 -15.776 -1.638 1.00 92.70 ? 608 NAG A O6 1 HETATM 8493 O O7 . NAG J 3 . ? -67.985 -20.760 -8.158 1.00 91.86 ? 608 NAG A O7 1 HETATM 8494 C C1 . NAG K 3 . ? -44.174 -30.696 -21.539 1.00 104.44 ? 609 NAG A C1 1 HETATM 8495 C C2 . NAG K 3 . ? -43.940 -31.287 -22.953 1.00 106.07 ? 609 NAG A C2 1 HETATM 8496 C C3 . NAG K 3 . ? -44.822 -32.499 -23.267 1.00 106.00 ? 609 NAG A C3 1 HETATM 8497 C C4 . NAG K 3 . ? -44.787 -33.547 -22.146 1.00 106.00 ? 609 NAG A C4 1 HETATM 8498 C C5 . NAG K 3 . ? -44.614 -32.974 -20.724 1.00 106.54 ? 609 NAG A C5 1 HETATM 8499 C C6 . NAG K 3 . ? -43.969 -34.032 -19.815 1.00 106.68 ? 609 NAG A C6 1 HETATM 8500 C C7 . NAG K 3 . ? -42.974 -29.661 -24.366 1.00 105.98 ? 609 NAG A C7 1 HETATM 8501 C C8 . NAG K 3 . ? -41.902 -30.505 -24.997 1.00 105.75 ? 609 NAG A C8 1 HETATM 8502 N N2 . NAG K 3 . ? -44.071 -30.301 -24.010 1.00 105.67 ? 609 NAG A N2 1 HETATM 8503 O O3 . NAG K 3 . ? -44.350 -33.072 -24.468 1.00 105.96 ? 609 NAG A O3 1 HETATM 8504 O O4 . NAG K 3 . ? -45.974 -34.315 -22.146 1.00 104.38 ? 609 NAG A O4 1 HETATM 8505 O O5 . NAG K 3 . ? -43.856 -31.754 -20.623 1.00 105.81 ? 609 NAG A O5 1 HETATM 8506 O O6 . NAG K 3 . ? -44.737 -35.217 -19.753 1.00 106.66 ? 609 NAG A O6 1 HETATM 8507 O O7 . NAG K 3 . ? -42.826 -28.458 -24.168 1.00 105.87 ? 609 NAG A O7 1 HETATM 8508 C C1 . NAG L 3 . ? -59.723 -34.954 15.478 1.00 98.33 ? 610 NAG A C1 1 HETATM 8509 C C2 . NAG L 3 . ? -59.039 -34.614 14.159 1.00 102.20 ? 610 NAG A C2 1 HETATM 8510 C C3 . NAG L 3 . ? -59.274 -35.709 13.114 1.00 103.63 ? 610 NAG A C3 1 HETATM 8511 C C4 . NAG L 3 . ? -58.933 -37.097 13.669 1.00 104.61 ? 610 NAG A C4 1 HETATM 8512 C C5 . NAG L 3 . ? -59.458 -37.272 15.101 1.00 104.16 ? 610 NAG A C5 1 HETATM 8513 C C6 . NAG L 3 . ? -58.896 -38.532 15.769 1.00 105.20 ? 610 NAG A C6 1 HETATM 8514 C C7 . NAG L 3 . ? -58.659 -32.261 13.761 1.00 102.58 ? 610 NAG A C7 1 HETATM 8515 C C8 . NAG L 3 . ? -59.144 -30.973 13.164 1.00 102.89 ? 610 NAG A C8 1 HETATM 8516 N N2 . NAG L 3 . ? -59.469 -33.313 13.679 1.00 102.10 ? 610 NAG A N2 1 HETATM 8517 O O3 . NAG L 3 . ? -58.482 -35.455 11.975 1.00 104.13 ? 610 NAG A O3 1 HETATM 8518 O O4 . NAG L 3 . ? -59.457 -38.105 12.814 1.00 105.37 ? 610 NAG A O4 1 HETATM 8519 O O5 . NAG L 3 . ? -59.123 -36.156 15.905 1.00 101.46 ? 610 NAG A O5 1 HETATM 8520 O O6 . NAG L 3 . ? -59.718 -38.926 16.857 1.00 106.19 ? 610 NAG A O6 1 HETATM 8521 O O7 . NAG L 3 . ? -57.558 -32.311 14.301 1.00 102.77 ? 610 NAG A O7 1 HETATM 8522 S S . SO4 M 5 . ? -64.651 -8.484 12.496 1.00 106.91 ? 611 SO4 A S 1 HETATM 8523 O O1 . SO4 M 5 . ? -63.720 -7.359 12.366 1.00 107.01 ? 611 SO4 A O1 1 HETATM 8524 O O2 . SO4 M 5 . ? -65.372 -8.653 11.234 1.00 106.42 ? 611 SO4 A O2 1 HETATM 8525 O O3 . SO4 M 5 . ? -63.833 -9.653 12.798 1.00 106.00 ? 611 SO4 A O3 1 HETATM 8526 O O4 . SO4 M 5 . ? -65.637 -8.288 13.560 1.00 105.68 ? 611 SO4 A O4 1 HETATM 8527 S S . SO4 N 5 . ? -44.291 -13.535 30.054 1.00 138.07 ? 612 SO4 A S 1 HETATM 8528 O O1 . SO4 N 5 . ? -44.056 -14.980 30.117 1.00 138.50 ? 612 SO4 A O1 1 HETATM 8529 O O2 . SO4 N 5 . ? -44.894 -13.212 28.765 1.00 138.15 ? 612 SO4 A O2 1 HETATM 8530 O O3 . SO4 N 5 . ? -45.199 -13.106 31.122 1.00 137.87 ? 612 SO4 A O3 1 HETATM 8531 O O4 . SO4 N 5 . ? -43.003 -12.857 30.175 1.00 138.39 ? 612 SO4 A O4 1 HETATM 8532 CL CL . CL O 6 . ? -41.690 -17.814 28.357 1.00 70.21 ? 613 CL A CL 1 HETATM 8533 C C4 . TCX P 2 . ? -57.489 -37.948 53.754 1.00 54.84 ? 601 TCX B C4 1 HETATM 8534 C C3 . TCX P 2 . ? -57.314 -36.451 54.011 1.00 54.79 ? 601 TCX B C3 1 HETATM 8535 N N . TCX P 2 . ? -55.956 -36.115 53.583 1.00 54.86 ? 601 TCX B N 1 HETATM 8536 P P . TCX P 2 . ? -55.133 -35.146 54.714 1.00 55.94 ? 601 TCX B P 1 HETATM 8537 O O3 . TCX P 2 . ? -53.591 -35.780 54.747 1.00 54.48 ? 601 TCX B O3 1 HETATM 8538 O O2 . TCX P 2 . ? -55.752 -34.872 56.107 1.00 53.64 ? 601 TCX B O2 1 HETATM 8539 C C1 . NAG Q 3 . ? -71.852 -51.759 58.538 1.00 108.74 ? 602 NAG B C1 1 HETATM 8540 C C2 . NAG Q 3 . ? -72.035 -51.848 57.014 1.00 113.26 ? 602 NAG B C2 1 HETATM 8541 C C3 . NAG Q 3 . ? -71.833 -53.211 56.348 1.00 114.46 ? 602 NAG B C3 1 HETATM 8542 C C4 . NAG Q 3 . ? -71.270 -54.342 57.204 1.00 116.08 ? 602 NAG B C4 1 HETATM 8543 C C5 . NAG Q 3 . ? -71.593 -54.167 58.689 1.00 114.35 ? 602 NAG B C5 1 HETATM 8544 C C6 . NAG Q 3 . ? -70.774 -55.142 59.532 1.00 114.65 ? 602 NAG B C6 1 HETATM 8545 C C7 . NAG Q 3 . ? -73.538 -50.417 55.740 1.00 115.90 ? 602 NAG B C7 1 HETATM 8546 C C8 . NAG Q 3 . ? -74.569 -50.632 54.655 1.00 115.61 ? 602 NAG B C8 1 HETATM 8547 N N2 . NAG Q 3 . ? -73.366 -51.380 56.649 1.00 114.72 ? 602 NAG B N2 1 HETATM 8548 O O3 . NAG Q 3 . ? -70.934 -53.024 55.285 1.00 114.62 ? 602 NAG B O3 1 HETATM 8549 O O4 . NAG Q 3 . ? -71.700 -55.603 56.690 1.00 119.98 ? 602 NAG B O4 1 HETATM 8550 O O5 . NAG Q 3 . ? -71.209 -52.878 59.113 1.00 111.50 ? 602 NAG B O5 1 HETATM 8551 O O6 . NAG Q 3 . ? -69.388 -54.915 59.328 1.00 115.53 ? 602 NAG B O6 1 HETATM 8552 O O7 . NAG Q 3 . ? -72.866 -49.388 55.779 1.00 116.32 ? 602 NAG B O7 1 HETATM 8553 C C1 . NAG R 3 . ? -70.566 -56.284 56.077 1.00 123.67 ? 603 NAG B C1 1 HETATM 8554 C C2 . NAG R 3 . ? -70.707 -57.811 56.027 1.00 124.94 ? 603 NAG B C2 1 HETATM 8555 C C3 . NAG R 3 . ? -69.915 -58.385 54.859 1.00 125.89 ? 603 NAG B C3 1 HETATM 8556 C C4 . NAG R 3 . ? -70.502 -57.858 53.564 1.00 126.42 ? 603 NAG B C4 1 HETATM 8557 C C5 . NAG R 3 . ? -70.651 -56.332 53.622 1.00 125.95 ? 603 NAG B C5 1 HETATM 8558 C C6 . NAG R 3 . ? -72.106 -55.907 53.429 1.00 125.89 ? 603 NAG B C6 1 HETATM 8559 C C7 . NAG R 3 . ? -70.813 -59.311 57.913 1.00 126.77 ? 603 NAG B C7 1 HETATM 8560 C C8 . NAG R 3 . ? -70.087 -60.606 58.184 1.00 126.59 ? 603 NAG B C8 1 HETATM 8561 N N2 . NAG R 3 . ? -70.157 -58.381 57.234 1.00 126.03 ? 603 NAG B N2 1 HETATM 8562 O O3 . NAG R 3 . ? -69.942 -59.795 54.845 1.00 125.78 ? 603 NAG B O3 1 HETATM 8563 O O4 . NAG R 3 . ? -69.689 -58.276 52.483 1.00 127.10 ? 603 NAG B O4 1 HETATM 8564 O O5 . NAG R 3 . ? -70.137 -55.757 54.821 1.00 125.20 ? 603 NAG B O5 1 HETATM 8565 O O6 . NAG R 3 . ? -72.170 -54.923 52.424 1.00 125.67 ? 603 NAG B O6 1 HETATM 8566 O O7 . NAG R 3 . ? -71.966 -59.117 58.294 1.00 126.98 ? 603 NAG B O7 1 HETATM 8567 C C1 . FUC S 4 . ? -68.631 -56.115 59.624 1.00 115.83 ? 604 FUC B C1 1 HETATM 8568 C C2 . FUC S 4 . ? -67.287 -56.216 58.882 1.00 115.39 ? 604 FUC B C2 1 HETATM 8569 C C3 . FUC S 4 . ? -66.251 -55.245 59.440 1.00 115.35 ? 604 FUC B C3 1 HETATM 8570 C C4 . FUC S 4 . ? -66.215 -55.248 60.967 1.00 115.64 ? 604 FUC B C4 1 HETATM 8571 C C5 . FUC S 4 . ? -67.612 -55.278 61.590 1.00 115.55 ? 604 FUC B C5 1 HETATM 8572 C C6 . FUC S 4 . ? -67.535 -55.559 63.088 1.00 115.09 ? 604 FUC B C6 1 HETATM 8573 O O2 . FUC S 4 . ? -67.434 -55.999 57.492 1.00 114.79 ? 604 FUC B O2 1 HETATM 8574 O O3 . FUC S 4 . ? -64.979 -55.588 58.937 1.00 114.67 ? 604 FUC B O3 1 HETATM 8575 O O4 . FUC S 4 . ? -65.466 -56.351 61.428 1.00 116.47 ? 604 FUC B O4 1 HETATM 8576 O O5 . FUC S 4 . ? -68.411 -56.284 61.009 1.00 115.99 ? 604 FUC B O5 1 HETATM 8577 C C1 . NAG T 3 . ? -42.238 -51.865 40.842 1.00 91.85 ? 605 NAG B C1 1 HETATM 8578 C C2 . NAG T 3 . ? -42.565 -53.112 40.018 1.00 94.82 ? 605 NAG B C2 1 HETATM 8579 C C3 . NAG T 3 . ? -43.733 -53.941 40.566 1.00 96.19 ? 605 NAG B C3 1 HETATM 8580 C C4 . NAG T 3 . ? -43.574 -54.208 42.054 1.00 98.06 ? 605 NAG B C4 1 HETATM 8581 C C5 . NAG T 3 . ? -43.257 -52.867 42.728 1.00 97.51 ? 605 NAG B C5 1 HETATM 8582 C C6 . NAG T 3 . ? -43.100 -52.986 44.243 1.00 99.94 ? 605 NAG B C6 1 HETATM 8583 C C7 . NAG T 3 . ? -41.989 -52.569 37.718 1.00 96.47 ? 605 NAG B C7 1 HETATM 8584 C C8 . NAG T 3 . ? -42.139 -53.396 36.459 1.00 96.10 ? 605 NAG B C8 1 HETATM 8585 N N2 . NAG T 3 . ? -42.908 -52.740 38.664 1.00 95.58 ? 605 NAG B N2 1 HETATM 8586 O O3 . NAG T 3 . ? -43.837 -55.162 39.859 1.00 95.30 ? 605 NAG B O3 1 HETATM 8587 O O4 . NAG T 3 . ? -44.772 -54.782 42.550 1.00 101.73 ? 605 NAG B O4 1 HETATM 8588 O O5 . NAG T 3 . ? -42.089 -52.273 42.184 1.00 93.91 ? 605 NAG B O5 1 HETATM 8589 O O6 . NAG T 3 . ? -42.348 -54.142 44.531 1.00 103.76 ? 605 NAG B O6 1 HETATM 8590 O O7 . NAG T 3 . ? -41.061 -51.767 37.865 1.00 96.51 ? 605 NAG B O7 1 HETATM 8591 C C1 . NAG U 3 . ? -44.651 -56.218 42.736 1.00 106.21 ? 606 NAG B C1 1 HETATM 8592 C C2 . NAG U 3 . ? -45.708 -56.734 43.726 1.00 108.09 ? 606 NAG B C2 1 HETATM 8593 C C3 . NAG U 3 . ? -45.372 -58.189 44.047 1.00 109.24 ? 606 NAG B C3 1 HETATM 8594 C C4 . NAG U 3 . ? -45.592 -58.977 42.761 1.00 109.52 ? 606 NAG B C4 1 HETATM 8595 C C5 . NAG U 3 . ? -44.952 -58.361 41.518 1.00 109.24 ? 606 NAG B C5 1 HETATM 8596 C C6 . NAG U 3 . ? -45.922 -58.723 40.402 1.00 110.33 ? 606 NAG B C6 1 HETATM 8597 C C7 . NAG U 3 . ? -46.986 -55.252 45.183 1.00 108.49 ? 606 NAG B C7 1 HETATM 8598 C C8 . NAG U 3 . ? -47.612 -55.438 46.541 1.00 108.08 ? 606 NAG B C8 1 HETATM 8599 N N2 . NAG U 3 . ? -45.853 -55.923 44.933 1.00 108.59 ? 606 NAG B N2 1 HETATM 8600 O O3 . NAG U 3 . ? -46.174 -58.716 45.095 1.00 109.23 ? 606 NAG B O3 1 HETATM 8601 O O4 . NAG U 3 . ? -45.124 -60.305 42.889 1.00 109.71 ? 606 NAG B O4 1 HETATM 8602 O O5 . NAG U 3 . ? -44.726 -56.948 41.517 1.00 107.93 ? 606 NAG B O5 1 HETATM 8603 O O6 . NAG U 3 . ? -45.497 -58.182 39.171 1.00 111.77 ? 606 NAG B O6 1 HETATM 8604 O O7 . NAG U 3 . ? -47.511 -54.509 44.347 1.00 107.56 ? 606 NAG B O7 1 HETATM 8605 C C1 . FUC V 4 . ? -41.338 -53.890 45.533 1.00 105.83 ? 607 FUC B C1 1 HETATM 8606 C C2 . FUC V 4 . ? -40.670 -55.226 45.766 1.00 106.46 ? 607 FUC B C2 1 HETATM 8607 C C3 . FUC V 4 . ? -40.133 -55.629 44.412 1.00 107.35 ? 607 FUC B C3 1 HETATM 8608 C C4 . FUC V 4 . ? -39.042 -54.649 44.003 1.00 107.90 ? 607 FUC B C4 1 HETATM 8609 C C5 . FUC V 4 . ? -39.564 -53.204 44.025 1.00 107.60 ? 607 FUC B C5 1 HETATM 8610 C C6 . FUC V 4 . ? -38.413 -52.202 43.904 1.00 107.09 ? 607 FUC B C6 1 HETATM 8611 O O2 . FUC V 4 . ? -41.632 -56.172 46.151 1.00 106.53 ? 607 FUC B O2 1 HETATM 8612 O O3 . FUC V 4 . ? -39.634 -56.941 44.453 1.00 107.93 ? 607 FUC B O3 1 HETATM 8613 O O4 . FUC V 4 . ? -37.924 -54.794 44.856 1.00 108.37 ? 607 FUC B O4 1 HETATM 8614 O O5 . FUC V 4 . ? -40.354 -52.923 45.180 1.00 106.96 ? 607 FUC B O5 1 HETATM 8615 C C1 . NAG W 3 . ? -55.446 -3.609 68.731 1.00 92.54 ? 608 NAG B C1 1 HETATM 8616 C C2 . NAG W 3 . ? -55.956 -2.573 69.752 1.00 94.69 ? 608 NAG B C2 1 HETATM 8617 C C3 . NAG W 3 . ? -57.475 -2.593 69.728 1.00 95.29 ? 608 NAG B C3 1 HETATM 8618 C C4 . NAG W 3 . ? -57.859 -2.111 68.320 1.00 95.76 ? 608 NAG B C4 1 HETATM 8619 C C5 . NAG W 3 . ? -57.298 -3.081 67.241 1.00 95.43 ? 608 NAG B C5 1 HETATM 8620 C C6 . NAG W 3 . ? -57.628 -2.694 65.775 1.00 94.72 ? 608 NAG B C6 1 HETATM 8621 C C7 . NAG W 3 . ? -54.247 -2.095 71.348 1.00 92.55 ? 608 NAG B C7 1 HETATM 8622 C C8 . NAG W 3 . ? -54.318 -0.601 71.474 1.00 92.11 ? 608 NAG B C8 1 HETATM 8623 N N2 . NAG W 3 . ? -55.399 -2.718 71.088 1.00 93.35 ? 608 NAG B N2 1 HETATM 8624 O O3 . NAG W 3 . ? -57.991 -1.773 70.753 1.00 95.43 ? 608 NAG B O3 1 HETATM 8625 O O4 . NAG W 3 . ? -59.264 -1.961 68.233 1.00 96.48 ? 608 NAG B O4 1 HETATM 8626 O O5 . NAG W 3 . ? -55.884 -3.255 67.408 1.00 94.36 ? 608 NAG B O5 1 HETATM 8627 O O6 . NAG W 3 . ? -57.925 -3.810 64.938 1.00 92.31 ? 608 NAG B O6 1 HETATM 8628 O O7 . NAG W 3 . ? -53.170 -2.689 71.451 1.00 91.58 ? 608 NAG B O7 1 HETATM 8629 C C1 . NAG X 3 . ? -38.944 -23.994 85.270 1.00 103.90 ? 609 NAG B C1 1 HETATM 8630 C C2 . NAG X 3 . ? -38.346 -24.090 86.679 1.00 105.40 ? 609 NAG B C2 1 HETATM 8631 C C3 . NAG X 3 . ? -37.382 -22.957 86.975 1.00 105.31 ? 609 NAG B C3 1 HETATM 8632 C C4 . NAG X 3 . ? -36.322 -22.833 85.882 1.00 105.48 ? 609 NAG B C4 1 HETATM 8633 C C5 . NAG X 3 . ? -36.826 -23.107 84.455 1.00 105.86 ? 609 NAG B C5 1 HETATM 8634 C C6 . NAG X 3 . ? -35.667 -23.591 83.575 1.00 106.03 ? 609 NAG B C6 1 HETATM 8635 C C7 . NAG X 3 . ? -39.778 -25.375 88.083 1.00 105.48 ? 609 NAG B C7 1 HETATM 8636 C C8 . NAG X 3 . ? -38.759 -26.263 88.743 1.00 105.06 ? 609 NAG B C8 1 HETATM 8637 N N2 . NAG X 3 . ? -39.363 -24.165 87.710 1.00 105.20 ? 609 NAG B N2 1 HETATM 8638 O O3 . NAG X 3 . ? -36.741 -23.267 88.189 1.00 105.24 ? 609 NAG B O3 1 HETATM 8639 O O4 . NAG X 3 . ? -35.745 -21.543 85.925 1.00 103.91 ? 609 NAG B O4 1 HETATM 8640 O O5 . NAG X 3 . ? -37.848 -24.097 84.371 1.00 105.27 ? 609 NAG B O5 1 HETATM 8641 O O6 . NAG X 3 . ? -34.646 -22.625 83.445 1.00 106.07 ? 609 NAG B O6 1 HETATM 8642 O O7 . NAG X 3 . ? -40.926 -25.770 87.876 1.00 105.46 ? 609 NAG B O7 1 HETATM 8643 C C1 . NAG Y 3 . ? -37.523 -8.205 48.178 1.00 97.95 ? 610 NAG B C1 1 HETATM 8644 C C2 . NAG Y 3 . ? -37.737 -8.965 49.479 1.00 101.69 ? 610 NAG B C2 1 HETATM 8645 C C3 . NAG Y 3 . ? -36.716 -8.524 50.512 1.00 103.01 ? 610 NAG B C3 1 HETATM 8646 C C4 . NAG Y 3 . ? -35.299 -8.645 49.944 1.00 104.12 ? 610 NAG B C4 1 HETATM 8647 C C5 . NAG Y 3 . ? -35.200 -8.128 48.497 1.00 103.69 ? 610 NAG B C5 1 HETATM 8648 C C6 . NAG Y 3 . ? -33.857 -8.477 47.843 1.00 104.54 ? 610 NAG B C6 1 HETATM 8649 C C7 . NAG Y 3 . ? -39.926 -9.871 49.901 1.00 102.16 ? 610 NAG B C7 1 HETATM 8650 C C8 . NAG Y 3 . ? -41.287 -9.686 50.500 1.00 102.46 ? 610 NAG B C8 1 HETATM 8651 N N2 . NAG Y 3 . ? -39.088 -8.834 49.984 1.00 101.60 ? 610 NAG B N2 1 HETATM 8652 O O3 . NAG Y 3 . ? -36.845 -9.362 51.633 1.00 103.57 ? 610 NAG B O3 1 HETATM 8653 O O4 . NAG Y 3 . ? -34.381 -7.965 50.788 1.00 104.97 ? 610 NAG B O4 1 HETATM 8654 O O5 . NAG Y 3 . ? -36.263 -8.631 47.699 1.00 101.02 ? 610 NAG B O5 1 HETATM 8655 O O6 . NAG Y 3 . ? -33.567 -7.571 46.797 1.00 105.55 ? 610 NAG B O6 1 HETATM 8656 O O7 . NAG Y 3 . ? -39.635 -10.942 49.362 1.00 102.38 ? 610 NAG B O7 1 HETATM 8657 S S . SO4 Z 5 . ? -64.632 -8.873 51.067 1.00 113.61 ? 611 SO4 B S 1 HETATM 8658 O O1 . SO4 Z 5 . ? -64.993 -8.425 49.720 1.00 113.76 ? 611 SO4 B O1 1 HETATM 8659 O O2 . SO4 Z 5 . ? -64.913 -7.793 52.015 1.00 112.32 ? 611 SO4 B O2 1 HETATM 8660 O O3 . SO4 Z 5 . ? -65.380 -10.100 51.388 1.00 113.18 ? 611 SO4 B O3 1 HETATM 8661 O O4 . SO4 Z 5 . ? -63.200 -9.150 51.131 1.00 113.91 ? 611 SO4 B O4 1 HETATM 8662 O O . HOH AA 7 . ? -28.188 -14.597 40.166 1.00 79.04 ? 701 HOH A O 1 HETATM 8663 O O . HOH AA 7 . ? -56.545 -31.017 -9.267 1.00 52.99 ? 702 HOH A O 1 HETATM 8664 O O . HOH AA 7 . ? -45.896 -12.340 14.529 1.00 50.99 ? 703 HOH A O 1 HETATM 8665 O O . HOH AA 7 . ? -48.891 -27.909 2.362 1.00 52.42 ? 704 HOH A O 1 HETATM 8666 O O . HOH AA 7 . ? -30.058 -7.939 -4.280 1.00 56.95 ? 705 HOH A O 1 HETATM 8667 O O . HOH AA 7 . ? -44.261 -22.291 -1.528 1.00 33.47 ? 706 HOH A O 1 HETATM 8668 O O . HOH AA 7 . ? -63.120 -27.257 13.544 1.00 50.91 ? 707 HOH A O 1 HETATM 8669 O O . HOH AA 7 . ? -68.015 -28.450 14.157 1.00 59.30 ? 708 HOH A O 1 HETATM 8670 O O . HOH AA 7 . ? -41.277 -17.774 13.803 1.00 50.00 ? 709 HOH A O 1 HETATM 8671 O O . HOH AA 7 . ? -27.738 -7.440 1.548 1.00 49.05 ? 710 HOH A O 1 HETATM 8672 O O . HOH AA 7 . ? -44.644 -17.666 14.446 1.00 41.63 ? 711 HOH A O 1 HETATM 8673 O O . HOH AA 7 . ? -23.955 -16.862 6.756 1.00 40.48 ? 712 HOH A O 1 HETATM 8674 O O . HOH AA 7 . ? -38.402 5.600 3.888 1.00 123.80 ? 713 HOH A O 1 HETATM 8675 O O . HOH AA 7 . ? -27.563 0.563 15.887 1.00 48.03 ? 714 HOH A O 1 HETATM 8676 O O . HOH AA 7 . ? -43.783 -32.411 -26.907 1.00 74.77 ? 715 HOH A O 1 HETATM 8677 O O . HOH AA 7 . ? -40.717 -17.167 5.956 1.00 27.63 ? 716 HOH A O 1 HETATM 8678 O O . HOH AA 7 . ? -43.688 -16.758 -1.183 1.00 70.20 ? 717 HOH A O 1 HETATM 8679 O O . HOH AA 7 . ? -24.505 -17.658 30.387 1.00 64.03 ? 718 HOH A O 1 HETATM 8680 O O . HOH AA 7 . ? -34.316 0.520 2.551 1.00 57.17 ? 719 HOH A O 1 HETATM 8681 O O . HOH AA 7 . ? -54.011 1.928 16.256 1.00 58.07 ? 720 HOH A O 1 HETATM 8682 O O . HOH AA 7 . ? -61.095 -24.111 19.353 1.00 57.64 ? 721 HOH A O 1 HETATM 8683 O O . HOH AA 7 . ? -29.705 -5.458 -15.162 1.00 58.28 ? 722 HOH A O 1 HETATM 8684 O O . HOH AA 7 . ? -34.526 -18.146 17.421 1.00 51.28 ? 723 HOH A O 1 HETATM 8685 O O . HOH AA 7 . ? -11.990 -20.480 21.566 1.00 68.49 ? 724 HOH A O 1 HETATM 8686 O O . HOH AA 7 . ? -37.226 -0.042 -0.953 1.00 49.67 ? 725 HOH A O 1 HETATM 8687 O O . HOH AA 7 . ? -40.379 -24.755 10.700 1.00 63.96 ? 726 HOH A O 1 HETATM 8688 O O . HOH AA 7 . ? -66.589 -16.465 0.708 1.00 52.87 ? 727 HOH A O 1 HETATM 8689 O O . HOH AA 7 . ? -22.714 -22.713 0.001 0.50 81.02 ? 728 HOH A O 1 HETATM 8690 O O . HOH AA 7 . ? -59.636 -8.431 18.314 1.00 68.44 ? 729 HOH A O 1 HETATM 8691 O O . HOH AA 7 . ? -38.612 -7.914 32.555 1.00 74.78 ? 730 HOH A O 1 HETATM 8692 O O . HOH AA 7 . ? -38.517 -12.313 28.188 1.00 44.50 ? 731 HOH A O 1 HETATM 8693 O O . HOH AA 7 . ? -43.847 -45.578 8.624 1.00 55.05 ? 732 HOH A O 1 HETATM 8694 O O . HOH AA 7 . ? -37.286 -12.049 2.551 1.00 51.84 ? 733 HOH A O 1 HETATM 8695 O O . HOH AA 7 . ? -37.384 -17.982 2.514 1.00 62.65 ? 734 HOH A O 1 HETATM 8696 O O . HOH AA 7 . ? -26.383 -24.416 1.544 1.00 61.94 ? 735 HOH A O 1 HETATM 8697 O O . HOH AA 7 . ? -34.567 -5.865 -10.265 1.00 42.07 ? 736 HOH A O 1 HETATM 8698 O O . HOH AA 7 . ? -45.690 2.125 -12.183 1.00 59.47 ? 737 HOH A O 1 HETATM 8699 O O . HOH AA 7 . ? -19.991 -13.081 34.622 1.00 46.54 ? 738 HOH A O 1 HETATM 8700 O O . HOH AA 7 . ? -45.348 -28.546 24.092 1.00 61.20 ? 739 HOH A O 1 HETATM 8701 O O . HOH AA 7 . ? -15.676 -19.531 17.032 1.00 71.60 ? 740 HOH A O 1 HETATM 8702 O O . HOH AA 7 . ? -24.271 -4.851 7.217 1.00 72.18 ? 741 HOH A O 1 HETATM 8703 O O . HOH AA 7 . ? -50.642 -9.933 25.036 1.00 70.96 ? 742 HOH A O 1 HETATM 8704 O O . HOH AA 7 . ? -46.080 -38.829 21.012 1.00 64.06 ? 743 HOH A O 1 HETATM 8705 O O . HOH AA 7 . ? -15.317 4.001 7.145 1.00 67.44 ? 744 HOH A O 1 HETATM 8706 O O . HOH AA 7 . ? -40.816 -37.535 4.909 1.00 58.35 ? 745 HOH A O 1 HETATM 8707 O O . HOH AA 7 . ? -58.950 -3.102 20.818 1.00 74.96 ? 746 HOH A O 1 HETATM 8708 O O . HOH AA 7 . ? -22.186 -11.618 37.038 1.00 41.48 ? 747 HOH A O 1 HETATM 8709 O O . HOH AA 7 . ? -16.460 -25.643 23.028 1.00 61.17 ? 748 HOH A O 1 HETATM 8710 O O . HOH AA 7 . ? -31.949 -4.744 12.103 1.00 53.21 ? 749 HOH A O 1 HETATM 8711 O O . HOH AA 7 . ? -24.396 -12.152 37.731 1.00 61.75 ? 750 HOH A O 1 HETATM 8712 O O . HOH AA 7 . ? -46.821 -2.762 -17.133 1.00 65.13 ? 751 HOH A O 1 HETATM 8713 O O . HOH AA 7 . ? -27.889 -14.015 10.311 1.00 51.15 ? 752 HOH A O 1 HETATM 8714 O O . HOH AA 7 . ? -38.702 7.838 6.739 1.00 70.64 ? 753 HOH A O 1 HETATM 8715 O O . HOH AA 7 . ? -31.247 -10.150 6.567 1.00 69.23 ? 754 HOH A O 1 HETATM 8716 O O . HOH AA 7 . ? -22.397 7.429 24.125 1.00 33.89 ? 755 HOH A O 1 HETATM 8717 O O . HOH AA 7 . ? -63.574 -2.972 24.470 1.00 57.37 ? 756 HOH A O 1 HETATM 8718 O O . HOH AA 7 . ? -26.553 -31.876 9.440 1.00 55.90 ? 757 HOH A O 1 HETATM 8719 O O . HOH AA 7 . ? -35.093 -29.462 -0.311 1.00 44.95 ? 758 HOH A O 1 HETATM 8720 O O . HOH AA 7 . ? -36.642 -29.216 6.187 1.00 37.78 ? 759 HOH A O 1 HETATM 8721 O O . HOH AA 7 . ? -60.704 -2.455 -2.063 1.00 91.08 ? 760 HOH A O 1 HETATM 8722 O O . HOH AA 7 . ? -34.498 -19.096 10.862 1.00 41.49 ? 761 HOH A O 1 HETATM 8723 O O . HOH AA 7 . ? -61.206 -0.870 4.566 1.00 58.10 ? 762 HOH A O 1 HETATM 8724 O O . HOH AA 7 . ? -55.448 -20.493 -25.998 1.00 70.68 ? 763 HOH A O 1 HETATM 8725 O O . HOH AA 7 . ? -31.821 -4.599 -22.522 1.00 62.90 ? 764 HOH A O 1 HETATM 8726 O O . HOH AA 7 . ? -52.353 -9.456 -13.798 1.00 76.09 ? 765 HOH A O 1 HETATM 8727 O O . HOH BA 7 . ? -60.992 -50.569 47.074 1.00 100.46 ? 701 HOH B O 1 HETATM 8728 O O . HOH BA 7 . ? -48.444 -7.552 69.483 1.00 111.50 ? 702 HOH B O 1 HETATM 8729 O O . HOH BA 7 . ? -59.251 -42.065 79.357 1.00 87.43 ? 703 HOH B O 1 HETATM 8730 O O . HOH BA 7 . ? -68.014 -43.119 65.814 1.00 69.81 ? 704 HOH B O 1 HETATM 8731 O O . HOH BA 7 . ? -73.056 -37.119 59.857 1.00 98.41 ? 705 HOH B O 1 HETATM 8732 O O . HOH BA 7 . ? -44.146 -27.597 65.234 1.00 53.44 ? 706 HOH B O 1 HETATM 8733 O O . HOH BA 7 . ? -50.628 -19.398 88.543 1.00 81.87 ? 707 HOH B O 1 HETATM 8734 O O . HOH BA 7 . ? -42.883 -20.358 61.165 1.00 55.88 ? 708 HOH B O 1 HETATM 8735 O O . HOH BA 7 . ? -63.678 -13.620 45.867 1.00 60.09 ? 709 HOH B O 1 HETATM 8736 O O . HOH BA 7 . ? -60.959 -22.878 87.972 1.00 88.35 ? 710 HOH B O 1 HETATM 8737 O O . HOH BA 7 . ? -55.718 -33.531 36.357 1.00 39.12 ? 711 HOH B O 1 HETATM 8738 O O . HOH BA 7 . ? -49.868 -14.371 34.422 1.00 63.99 ? 712 HOH B O 1 HETATM 8739 O O . HOH BA 7 . ? -47.261 -26.247 65.285 1.00 54.72 ? 713 HOH B O 1 HETATM 8740 O O . HOH BA 7 . ? -55.550 -39.278 71.414 1.00 70.59 ? 714 HOH B O 1 HETATM 8741 O O . HOH BA 7 . ? -59.125 -43.495 59.213 1.00 50.49 ? 715 HOH B O 1 HETATM 8742 O O . HOH BA 7 . ? -51.339 -43.560 22.249 1.00 52.47 ? 716 HOH B O 1 HETATM 8743 O O . HOH BA 7 . ? -67.539 -37.082 64.500 1.00 41.45 ? 717 HOH B O 1 HETATM 8744 O O . HOH BA 7 . ? -49.258 -11.555 80.913 1.00 76.66 ? 718 HOH B O 1 HETATM 8745 O O . HOH BA 7 . ? -50.899 -29.330 35.972 1.00 42.02 ? 719 HOH B O 1 HETATM 8746 O O . HOH BA 7 . ? -44.586 -29.012 53.034 1.00 60.69 ? 720 HOH B O 1 HETATM 8747 O O . HOH BA 7 . ? -48.070 -33.779 78.194 1.00 84.26 ? 721 HOH B O 1 HETATM 8748 O O . HOH BA 7 . ? -72.764 -33.053 53.782 1.00 83.56 ? 722 HOH B O 1 HETATM 8749 O O . HOH BA 7 . ? -61.423 -14.798 39.415 1.00 99.34 ? 723 HOH B O 1 HETATM 8750 O O . HOH BA 7 . ? -57.749 -15.968 42.823 1.00 68.27 ? 724 HOH B O 1 HETATM 8751 O O . HOH BA 7 . ? -44.267 -5.852 44.518 1.00 89.93 ? 725 HOH B O 1 HETATM 8752 O O . HOH BA 7 . ? -58.417 -42.378 68.332 1.00 96.81 ? 726 HOH B O 1 HETATM 8753 O O . HOH BA 7 . ? -49.147 -36.283 46.212 1.00 64.59 ? 727 HOH B O 1 HETATM 8754 O O . HOH BA 7 . ? -51.615 -26.280 48.817 1.00 36.43 ? 728 HOH B O 1 HETATM 8755 O O . HOH BA 7 . ? -54.410 -32.766 78.404 1.00 56.13 ? 729 HOH B O 1 HETATM 8756 O O . HOH BA 7 . ? -56.049 -35.000 61.360 1.00 41.71 ? 730 HOH B O 1 HETATM 8757 O O . HOH BA 7 . ? -71.477 -24.106 67.258 1.00 69.18 ? 731 HOH B O 1 HETATM 8758 O O . HOH BA 7 . ? -48.254 -41.646 62.890 1.00 54.75 ? 732 HOH B O 1 HETATM 8759 O O . HOH BA 7 . ? -79.793 -45.949 80.923 1.00 57.54 ? 733 HOH B O 1 HETATM 8760 O O . HOH BA 7 . ? -38.672 -16.755 84.622 1.00 88.27 ? 734 HOH B O 1 HETATM 8761 O O . HOH BA 7 . ? -54.069 -30.648 79.581 1.00 70.93 ? 735 HOH B O 1 HETATM 8762 O O . HOH BA 7 . ? -73.037 -47.218 57.450 1.00 160.61 ? 736 HOH B O 1 HETATM 8763 O O . HOH BA 7 . ? -57.556 -26.261 49.780 1.00 47.85 ? 737 HOH B O 1 HETATM 8764 O O . HOH BA 7 . ? -48.692 -8.910 44.861 1.00 45.79 ? 738 HOH B O 1 HETATM 8765 O O . HOH BA 7 . ? -72.181 -51.114 36.427 1.00 70.32 ? 739 HOH B O 1 HETATM 8766 O O . HOH BA 7 . ? -62.845 -46.723 54.462 1.00 75.78 ? 740 HOH B O 1 HETATM 8767 O O . HOH BA 7 . ? -72.883 -25.705 61.674 1.00 80.10 ? 741 HOH B O 1 HETATM 8768 O O . HOH BA 7 . ? -61.547 -1.210 66.732 1.00 59.29 ? 742 HOH B O 1 HETATM 8769 O O . HOH BA 7 . ? -36.330 -17.216 43.430 1.00 88.48 ? 743 HOH B O 1 HETATM 8770 O O . HOH BA 7 . ? -54.781 -25.864 85.580 1.00 75.29 ? 744 HOH B O 1 HETATM 8771 O O . HOH BA 7 . ? -56.631 -4.934 51.044 1.00 52.24 ? 745 HOH B O 1 HETATM 8772 O O . HOH BA 7 . ? -40.664 -11.268 73.172 1.00 72.89 ? 746 HOH B O 1 HETATM 8773 O O . HOH BA 7 . ? -67.005 -44.929 82.986 1.00 64.37 ? 747 HOH B O 1 HETATM 8774 O O . HOH BA 7 . ? -60.138 -48.366 56.767 1.00 58.52 ? 748 HOH B O 1 HETATM 8775 O O . HOH BA 7 . ? -35.279 -25.431 44.042 1.00 51.16 ? 749 HOH B O 1 HETATM 8776 O O . HOH BA 7 . ? -51.357 -34.209 69.070 1.00 60.87 ? 750 HOH B O 1 HETATM 8777 O O . HOH BA 7 . ? -78.524 -40.073 71.972 1.00 63.80 ? 751 HOH B O 1 HETATM 8778 O O . HOH BA 7 . ? -42.609 -12.863 79.240 1.00 68.76 ? 752 HOH B O 1 HETATM 8779 O O . HOH BA 7 . ? -50.092 -33.192 61.795 1.00 70.80 ? 753 HOH B O 1 HETATM 8780 O O . HOH BA 7 . ? -65.202 -32.105 43.828 1.00 62.65 ? 754 HOH B O 1 HETATM 8781 O O . HOH BA 7 . ? -32.207 -9.939 49.904 1.00 89.25 ? 755 HOH B O 1 HETATM 8782 O O . HOH BA 7 . ? -49.540 -3.605 66.580 1.00 77.01 ? 756 HOH B O 1 HETATM 8783 O O . HOH BA 7 . ? -37.649 -31.162 52.319 1.00 46.92 ? 757 HOH B O 1 HETATM 8784 O O . HOH BA 7 . ? -42.019 -45.824 58.693 1.00 79.14 ? 758 HOH B O 1 HETATM 8785 O O . HOH BA 7 . ? -65.722 -51.502 50.625 1.00 62.34 ? 759 HOH B O 1 HETATM 8786 O O . HOH BA 7 . ? -52.241 -54.756 31.273 1.00 77.37 ? 760 HOH B O 1 HETATM 8787 O O . HOH BA 7 . ? -55.794 -27.711 34.045 1.00 34.58 ? 761 HOH B O 1 HETATM 8788 O O . HOH BA 7 . ? -37.920 -17.176 78.420 1.00 107.32 ? 762 HOH B O 1 HETATM 8789 O O . HOH BA 7 . ? -53.291 -27.935 35.304 1.00 44.59 ? 763 HOH B O 1 HETATM 8790 O O . HOH BA 7 . ? -61.238 -14.035 79.826 1.00 75.61 ? 764 HOH B O 1 HETATM 8791 O O . HOH BA 7 . ? -53.647 -47.776 25.465 1.00 73.07 ? 765 HOH B O 1 HETATM 8792 O O . HOH BA 7 . ? -39.521 -32.810 53.229 1.00 71.65 ? 766 HOH B O 1 HETATM 8793 O O . HOH BA 7 . ? -75.385 -36.852 57.377 1.00 78.01 ? 767 HOH B O 1 HETATM 8794 O O . HOH BA 7 . ? -71.270 -13.174 58.943 1.00 46.48 ? 768 HOH B O 1 HETATM 8795 O O . HOH BA 7 . ? -51.773 -24.880 35.480 1.00 72.37 ? 769 HOH B O 1 HETATM 8796 O O . HOH BA 7 . ? -63.654 -41.817 87.096 1.00 57.91 ? 770 HOH B O 1 HETATM 8797 O O . HOH BA 7 . ? -68.823 -12.499 66.175 1.00 72.51 ? 771 HOH B O 1 HETATM 8798 O O . HOH BA 7 . ? -60.670 -17.295 90.205 1.00 75.08 ? 772 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 1 ? ? ? A . n A 1 2 ASP 2 2 2 ASP ASP A . n A 1 3 ASP 3 3 3 ASP ASP A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 ILE 5 5 5 ILE ILE A . n A 1 6 ILE 6 6 6 ILE ILE A . n A 1 7 ALA 7 7 7 ALA ALA A . n A 1 8 THR 8 8 8 THR THR A . n A 1 9 LYS 9 9 9 LYS LYS A . n A 1 10 ASN 10 10 10 ASN ASN A . n A 1 11 GLY 11 11 11 GLY GLY A . n A 1 12 LYS 12 12 12 LYS LYS A . n A 1 13 VAL 13 13 13 VAL VAL A . n A 1 14 ARG 14 14 14 ARG ARG A . n A 1 15 GLY 15 15 15 GLY GLY A . n A 1 16 MET 16 16 16 MET MET A . n A 1 17 GLN 17 17 17 GLN GLN A . n A 1 18 LEU 18 18 18 LEU LEU A . n A 1 19 THR 19 19 19 THR THR A . n A 1 20 VAL 20 20 20 VAL VAL A . n A 1 21 PHE 21 21 21 PHE PHE A . n A 1 22 GLY 22 22 22 GLY GLY A . n A 1 23 GLY 23 23 23 GLY GLY A . n A 1 24 THR 24 24 24 THR THR A . n A 1 25 VAL 25 25 25 VAL VAL A . n A 1 26 THR 26 26 26 THR THR A . n A 1 27 ALA 27 27 27 ALA ALA A . n A 1 28 PHE 28 28 28 PHE PHE A . n A 1 29 LEU 29 29 29 LEU LEU A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 ILE 31 31 31 ILE ILE A . n A 1 32 PRO 32 32 32 PRO PRO A . n A 1 33 TYR 33 33 33 TYR TYR A . n A 1 34 ALA 34 34 34 ALA ALA A . n A 1 35 GLN 35 35 35 GLN GLN A . n A 1 36 PRO 36 36 36 PRO PRO A . n A 1 37 PRO 37 37 37 PRO PRO A . n A 1 38 LEU 38 38 38 LEU LEU A . n A 1 39 GLY 39 39 39 GLY GLY A . n A 1 40 ARG 40 40 40 ARG ARG A . n A 1 41 LEU 41 41 41 LEU LEU A . n A 1 42 ARG 42 42 42 ARG ARG A . n A 1 43 PHE 43 43 43 PHE PHE A . n A 1 44 LYS 44 44 44 LYS LYS A . n A 1 45 LYS 45 45 45 LYS LYS A . n A 1 46 PRO 46 46 46 PRO PRO A . n A 1 47 GLN 47 47 47 GLN GLN A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 LEU 49 49 49 LEU LEU A . n A 1 50 THR 50 50 50 THR THR A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 TRP 52 52 52 TRP TRP A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 ASP 54 54 54 ASP ASP A . n A 1 55 ILE 55 55 55 ILE ILE A . n A 1 56 TRP 56 56 56 TRP TRP A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 ALA 58 58 58 ALA ALA A . n A 1 59 THR 59 59 59 THR THR A . n A 1 60 LYS 60 60 60 LYS LYS A . n A 1 61 TYR 61 61 61 TYR TYR A . n A 1 62 ALA 62 62 62 ALA ALA A . n A 1 63 ASN 63 63 63 ASN ASN A . n A 1 64 SER 64 64 64 SER SER A . n A 1 65 CYS 65 65 65 CYS CYS A . n A 1 66 CYS 66 66 66 CYS CYS A . n A 1 67 GLN 67 67 67 GLN GLN A . n A 1 68 ASN 68 68 68 ASN ASN A . n A 1 69 ILE 69 69 69 ILE ILE A . n A 1 70 ASP 70 70 70 ASP ASP A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 SER 72 72 72 SER SER A . n A 1 73 PHE 73 73 73 PHE PHE A . n A 1 74 PRO 74 74 74 PRO PRO A . n A 1 75 GLY 75 75 75 GLY GLY A . n A 1 76 PHE 76 76 76 PHE PHE A . n A 1 77 HIS 77 77 77 HIS HIS A . n A 1 78 GLY 78 78 78 GLY GLY A . n A 1 79 SER 79 79 79 SER SER A . n A 1 80 GLU 80 80 80 GLU GLU A . n A 1 81 MET 81 81 81 MET MET A . n A 1 82 TRP 82 82 82 TRP TRP A . n A 1 83 ASN 83 83 83 ASN ASN A . n A 1 84 PRO 84 84 84 PRO PRO A . n A 1 85 ASN 85 85 85 ASN ASN A . n A 1 86 THR 86 86 86 THR THR A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 LEU 88 88 88 LEU LEU A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 ASP 91 91 91 ASP ASP A . n A 1 92 CYS 92 92 92 CYS CYS A . n A 1 93 LEU 93 93 93 LEU LEU A . n A 1 94 TYR 94 94 94 TYR TYR A . n A 1 95 LEU 95 95 95 LEU LEU A . n A 1 96 ASN 96 96 96 ASN ASN A . n A 1 97 VAL 97 97 97 VAL VAL A . n A 1 98 TRP 98 98 98 TRP TRP A . n A 1 99 ILE 99 99 99 ILE ILE A . n A 1 100 PRO 100 100 100 PRO PRO A . n A 1 101 ALA 101 101 101 ALA ALA A . n A 1 102 PRO 102 102 102 PRO PRO A . n A 1 103 LYS 103 103 103 LYS LYS A . n A 1 104 PRO 104 104 104 PRO PRO A . n A 1 105 LYS 105 105 105 LYS LYS A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ALA 107 107 107 ALA ALA A . n A 1 108 THR 108 108 108 THR THR A . n A 1 109 VAL 109 109 109 VAL VAL A . n A 1 110 LEU 110 110 110 LEU LEU A . n A 1 111 ILE 111 111 111 ILE ILE A . n A 1 112 TRP 112 112 112 TRP TRP A . n A 1 113 ILE 113 113 113 ILE ILE A . n A 1 114 TYR 114 114 114 TYR TYR A . n A 1 115 GLY 115 115 115 GLY GLY A . n A 1 116 GLY 116 116 116 GLY GLY A . n A 1 117 GLY 117 117 117 GLY GLY A . n A 1 118 PHE 118 118 118 PHE PHE A . n A 1 119 GLN 119 119 119 GLN GLN A . n A 1 120 THR 120 120 120 THR THR A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 THR 122 122 122 THR THR A . n A 1 123 SER 123 123 123 SER SER A . n A 1 124 SER 124 124 124 SER SER A . n A 1 125 LEU 125 125 125 LEU LEU A . n A 1 126 HIS 126 126 126 HIS HIS A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 TYR 128 128 128 TYR TYR A . n A 1 129 ASP 129 129 129 ASP ASP A . n A 1 130 GLY 130 130 130 GLY GLY A . n A 1 131 LYS 131 131 131 LYS LYS A . n A 1 132 PHE 132 132 132 PHE PHE A . n A 1 133 LEU 133 133 133 LEU LEU A . n A 1 134 ALA 134 134 134 ALA ALA A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 VAL 136 136 136 VAL VAL A . n A 1 137 GLU 137 137 137 GLU GLU A . n A 1 138 ARG 138 138 138 ARG ARG A . n A 1 139 VAL 139 139 139 VAL VAL A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 VAL 141 141 141 VAL VAL A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 SER 143 143 143 SER SER A . n A 1 144 MET 144 144 144 MET MET A . n A 1 145 ASN 145 145 145 ASN ASN A . n A 1 146 TYR 146 146 146 TYR TYR A . n A 1 147 ARG 147 147 147 ARG ARG A . n A 1 148 VAL 148 148 148 VAL VAL A . n A 1 149 GLY 149 149 149 GLY GLY A . n A 1 150 ALA 150 150 150 ALA ALA A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 GLY 152 152 152 GLY GLY A . n A 1 153 PHE 153 153 153 PHE PHE A . n A 1 154 LEU 154 154 154 LEU LEU A . n A 1 155 ALA 155 155 155 ALA ALA A . n A 1 156 LEU 156 156 156 LEU LEU A . n A 1 157 PRO 157 157 157 PRO PRO A . n A 1 158 GLY 158 158 158 GLY GLY A . n A 1 159 ASN 159 159 159 ASN ASN A . n A 1 160 PRO 160 160 160 PRO PRO A . n A 1 161 GLU 161 161 161 GLU GLU A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 PRO 163 163 163 PRO PRO A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 ASN 165 165 165 ASN ASN A . n A 1 166 MET 166 166 166 MET MET A . n A 1 167 GLY 167 167 167 GLY GLY A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 PHE 169 169 169 PHE PHE A . n A 1 170 ASP 170 170 170 ASP ASP A . n A 1 171 GLN 171 171 171 GLN GLN A . n A 1 172 GLN 172 172 172 GLN GLN A . n A 1 173 LEU 173 173 173 LEU LEU A . n A 1 174 ALA 174 174 174 ALA ALA A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 GLN 176 176 176 GLN GLN A . n A 1 177 TRP 177 177 177 TRP TRP A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 GLN 179 179 179 GLN GLN A . n A 1 180 LYS 180 180 180 LYS LYS A . n A 1 181 ASN 181 181 181 ASN ASN A . n A 1 182 ILE 182 182 182 ILE ILE A . n A 1 183 ALA 183 183 183 ALA ALA A . n A 1 184 ALA 184 184 184 ALA ALA A . n A 1 185 PHE 185 185 185 PHE PHE A . n A 1 186 GLY 186 186 186 GLY GLY A . n A 1 187 GLY 187 187 187 GLY GLY A . n A 1 188 ASN 188 188 188 ASN ASN A . n A 1 189 PRO 189 189 189 PRO PRO A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 SER 191 191 191 SER SER A . n A 1 192 VAL 192 192 192 VAL VAL A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 LEU 194 194 194 LEU LEU A . n A 1 195 PHE 195 195 195 PHE PHE A . n A 1 196 GLY 196 196 196 GLY GLY A . n A 1 197 GLU 197 197 197 GLU GLU A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 GLY 200 200 200 GLY GLY A . n A 1 201 ALA 201 201 201 ALA ALA A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 VAL 204 204 204 VAL VAL A . n A 1 205 SER 205 205 205 SER SER A . n A 1 206 LEU 206 206 206 LEU LEU A . n A 1 207 HIS 207 207 207 HIS HIS A . n A 1 208 LEU 208 208 208 LEU LEU A . n A 1 209 LEU 209 209 209 LEU LEU A . n A 1 210 SER 210 210 210 SER SER A . n A 1 211 PRO 211 211 211 PRO PRO A . n A 1 212 GLY 212 212 212 GLY GLY A . n A 1 213 SER 213 213 213 SER SER A . n A 1 214 HIS 214 214 214 HIS HIS A . n A 1 215 SER 215 215 215 SER SER A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 PHE 217 217 217 PHE PHE A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 ARG 219 219 219 ARG ARG A . n A 1 220 ALA 220 220 220 ALA ALA A . n A 1 221 ILE 221 221 221 ILE ILE A . n A 1 222 LEU 222 222 222 LEU LEU A . n A 1 223 GLN 223 223 223 GLN GLN A . n A 1 224 SER 224 224 224 SER SER A . n A 1 225 GLY 225 225 225 GLY GLY A . n A 1 226 SER 226 226 226 SER SER A . n A 1 227 PHE 227 227 227 PHE PHE A . n A 1 228 ASN 228 228 228 ASN ASN A . n A 1 229 ALA 229 229 229 ALA ALA A . n A 1 230 PRO 230 230 230 PRO PRO A . n A 1 231 TRP 231 231 231 TRP TRP A . n A 1 232 ALA 232 232 232 ALA ALA A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 THR 234 234 234 THR THR A . n A 1 235 SER 235 235 235 SER SER A . n A 1 236 LEU 236 236 236 LEU LEU A . n A 1 237 TYR 237 237 237 TYR TYR A . n A 1 238 GLU 238 238 238 GLU GLU A . n A 1 239 ALA 239 239 239 ALA ALA A . n A 1 240 ARG 240 240 240 ARG ARG A . n A 1 241 ASN 241 241 241 ASN ASN A . n A 1 242 ARG 242 242 242 ARG ARG A . n A 1 243 THR 243 243 243 THR THR A . n A 1 244 LEU 244 244 244 LEU LEU A . n A 1 245 ASN 245 245 245 ASN ASN A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 ALA 247 247 247 ALA ALA A . n A 1 248 LYS 248 248 248 LYS LYS A . n A 1 249 LEU 249 249 249 LEU LEU A . n A 1 250 THR 250 250 250 THR THR A . n A 1 251 GLY 251 251 251 GLY GLY A . n A 1 252 CYS 252 252 252 CYS CYS A . n A 1 253 SER 253 253 253 SER SER A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 GLU 255 255 255 GLU GLU A . n A 1 256 ASN 256 256 256 ASN ASN A . n A 1 257 GLU 257 257 257 GLU GLU A . n A 1 258 THR 258 258 258 THR THR A . n A 1 259 GLU 259 259 259 GLU GLU A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 ILE 261 261 261 ILE ILE A . n A 1 262 LYS 262 262 262 LYS LYS A . n A 1 263 CYS 263 263 263 CYS CYS A . n A 1 264 LEU 264 264 264 LEU LEU A . n A 1 265 ARG 265 265 265 ARG ARG A . n A 1 266 ASN 266 266 266 ASN ASN A . n A 1 267 LYS 267 267 267 LYS LYS A . n A 1 268 ASP 268 268 268 ASP ASP A . n A 1 269 PRO 269 269 269 PRO PRO A . n A 1 270 GLN 270 270 270 GLN GLN A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 ILE 272 272 272 ILE ILE A . n A 1 273 LEU 273 273 273 LEU LEU A . n A 1 274 LEU 274 274 274 LEU LEU A . n A 1 275 ASN 275 275 275 ASN ASN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 ALA 277 277 277 ALA ALA A . n A 1 278 PHE 278 278 278 PHE PHE A . n A 1 279 VAL 279 279 279 VAL VAL A . n A 1 280 VAL 280 280 280 VAL VAL A . n A 1 281 PRO 281 281 281 PRO PRO A . n A 1 282 TYR 282 282 282 TYR TYR A . n A 1 283 GLY 283 283 283 GLY GLY A . n A 1 284 THR 284 284 284 THR THR A . n A 1 285 PRO 285 285 285 PRO PRO A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 SER 287 287 287 SER SER A . n A 1 288 VAL 288 288 288 VAL VAL A . n A 1 289 ASN 289 289 289 ASN ASN A . n A 1 290 PHE 290 290 290 PHE PHE A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 PRO 292 292 292 PRO PRO A . n A 1 293 THR 293 293 293 THR THR A . n A 1 294 VAL 294 294 294 VAL VAL A . n A 1 295 ASP 295 295 295 ASP ASP A . n A 1 296 GLY 296 296 296 GLY GLY A . n A 1 297 ASP 297 297 297 ASP ASP A . n A 1 298 PHE 298 298 298 PHE PHE A . n A 1 299 LEU 299 299 299 LEU LEU A . n A 1 300 THR 300 300 300 THR THR A . n A 1 301 ASP 301 301 301 ASP ASP A . n A 1 302 MET 302 302 302 MET MET A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ASP 304 304 304 ASP ASP A . n A 1 305 ILE 305 305 305 ILE ILE A . n A 1 306 LEU 306 306 306 LEU LEU A . n A 1 307 LEU 307 307 307 LEU LEU A . n A 1 308 GLU 308 308 308 GLU GLU A . n A 1 309 LEU 309 309 309 LEU LEU A . n A 1 310 GLY 310 310 310 GLY GLY A . n A 1 311 GLN 311 311 311 GLN GLN A . n A 1 312 PHE 312 312 312 PHE PHE A . n A 1 313 LYS 313 313 313 LYS LYS A . n A 1 314 LYS 314 314 314 LYS LYS A . n A 1 315 THR 315 315 315 THR THR A . n A 1 316 GLN 316 316 316 GLN GLN A . n A 1 317 ILE 317 317 317 ILE ILE A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 GLY 320 320 320 GLY GLY A . n A 1 321 VAL 321 321 321 VAL VAL A . n A 1 322 ASN 322 322 322 ASN ASN A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 ASP 324 324 324 ASP ASP A . n A 1 325 GLU 325 325 325 GLU GLU A . n A 1 326 GLY 326 326 326 GLY GLY A . n A 1 327 THR 327 327 327 THR THR A . n A 1 328 ALA 328 328 328 ALA ALA A . n A 1 329 PHE 329 329 329 PHE PHE A . n A 1 330 LEU 330 330 330 LEU LEU A . n A 1 331 VAL 331 331 331 VAL VAL A . n A 1 332 TYR 332 332 332 TYR TYR A . n A 1 333 GLY 333 333 333 GLY GLY A . n A 1 334 ALA 334 334 334 ALA ALA A . n A 1 335 PRO 335 335 335 PRO PRO A . n A 1 336 GLY 336 336 336 GLY GLY A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 SER 338 338 338 SER SER A . n A 1 339 LYS 339 339 339 LYS LYS A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 ASN 342 342 342 ASN ASN A . n A 1 343 SER 343 343 343 SER SER A . n A 1 344 ILE 344 344 344 ILE ILE A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 THR 346 346 346 THR THR A . n A 1 347 ARG 347 347 347 ARG ARG A . n A 1 348 LYS 348 348 348 LYS LYS A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 GLN 351 351 351 GLN GLN A . n A 1 352 GLU 352 352 352 GLU GLU A . n A 1 353 GLY 353 353 353 GLY GLY A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 LYS 355 355 355 LYS LYS A . n A 1 356 ILE 356 356 356 ILE ILE A . n A 1 357 PHE 357 357 357 PHE PHE A . n A 1 358 PHE 358 358 358 PHE PHE A . n A 1 359 PRO 359 359 359 PRO PRO A . n A 1 360 GLY 360 360 360 GLY GLY A . n A 1 361 VAL 361 361 361 VAL VAL A . n A 1 362 SER 362 362 362 SER SER A . n A 1 363 GLU 363 363 363 GLU GLU A . n A 1 364 PHE 364 364 364 PHE PHE A . n A 1 365 GLY 365 365 365 GLY GLY A . n A 1 366 LYS 366 366 366 LYS LYS A . n A 1 367 GLU 367 367 367 GLU GLU A . n A 1 368 SER 368 368 368 SER SER A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 LEU 370 370 370 LEU LEU A . n A 1 371 PHE 371 371 371 PHE PHE A . n A 1 372 HIS 372 372 372 HIS HIS A . n A 1 373 TYR 373 373 373 TYR TYR A . n A 1 374 THR 374 374 374 THR THR A . n A 1 375 ASP 375 375 375 ASP ASP A . n A 1 376 TRP 376 376 376 TRP TRP A . n A 1 377 VAL 377 377 377 VAL VAL A . n A 1 378 ASP 378 378 ? ? ? A . n A 1 379 ASP 379 379 ? ? ? A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 ARG 381 381 381 ARG ARG A . n A 1 382 PRO 382 382 382 PRO PRO A . n A 1 383 GLU 383 383 383 GLU GLU A . n A 1 384 ASN 384 384 384 ASN ASN A . n A 1 385 TYR 385 385 385 TYR TYR A . n A 1 386 ARG 386 386 386 ARG ARG A . n A 1 387 GLU 387 387 387 GLU GLU A . n A 1 388 ALA 388 388 388 ALA ALA A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 GLY 390 390 390 GLY GLY A . n A 1 391 ASP 391 391 391 ASP ASP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 VAL 393 393 393 VAL VAL A . n A 1 394 GLY 394 394 394 GLY GLY A . n A 1 395 ASP 395 395 395 ASP ASP A . n A 1 396 TYR 396 396 396 TYR TYR A . n A 1 397 ASN 397 397 397 ASN ASN A . n A 1 398 PHE 398 398 398 PHE PHE A . n A 1 399 ILE 399 399 399 ILE ILE A . n A 1 400 CYS 400 400 400 CYS CYS A . n A 1 401 PRO 401 401 401 PRO PRO A . n A 1 402 ALA 402 402 402 ALA ALA A . n A 1 403 LEU 403 403 403 LEU LEU A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 LYS 407 407 407 LYS LYS A . n A 1 408 LYS 408 408 408 LYS LYS A . n A 1 409 PHE 409 409 409 PHE PHE A . n A 1 410 SER 410 410 410 SER SER A . n A 1 411 GLU 411 411 411 GLU GLU A . n A 1 412 TRP 412 412 412 TRP TRP A . n A 1 413 GLY 413 413 413 GLY GLY A . n A 1 414 ASN 414 414 414 ASN ASN A . n A 1 415 ASN 415 415 415 ASN ASN A . n A 1 416 ALA 416 416 416 ALA ALA A . n A 1 417 PHE 417 417 417 PHE PHE A . n A 1 418 PHE 418 418 418 PHE PHE A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 TYR 420 420 420 TYR TYR A . n A 1 421 PHE 421 421 421 PHE PHE A . n A 1 422 GLU 422 422 422 GLU GLU A . n A 1 423 HIS 423 423 423 HIS HIS A . n A 1 424 ARG 424 424 424 ARG ARG A . n A 1 425 SER 425 425 425 SER SER A . n A 1 426 SER 426 426 426 SER SER A . n A 1 427 LYS 427 427 427 LYS LYS A . n A 1 428 LEU 428 428 428 LEU LEU A . n A 1 429 PRO 429 429 429 PRO PRO A . n A 1 430 TRP 430 430 430 TRP TRP A . n A 1 431 PRO 431 431 431 PRO PRO A . n A 1 432 GLU 432 432 432 GLU GLU A . n A 1 433 TRP 433 433 433 TRP TRP A . n A 1 434 MET 434 434 434 MET MET A . n A 1 435 GLY 435 435 435 GLY GLY A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 MET 437 437 437 MET MET A . n A 1 438 HIS 438 438 438 HIS HIS A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 TYR 440 440 440 TYR TYR A . n A 1 441 GLU 441 441 441 GLU GLU A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 GLU 443 443 443 GLU GLU A . n A 1 444 PHE 444 444 444 PHE PHE A . n A 1 445 VAL 445 445 445 VAL VAL A . n A 1 446 PHE 446 446 446 PHE PHE A . n A 1 447 GLY 447 447 447 GLY GLY A . n A 1 448 LEU 448 448 448 LEU LEU A . n A 1 449 PRO 449 449 449 PRO PRO A . n A 1 450 LEU 450 450 450 LEU LEU A . n A 1 451 GLU 451 451 451 GLU GLU A . n A 1 452 ARG 452 452 452 ARG ARG A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ASP 454 454 454 ASP ASP A . n A 1 455 ASN 455 455 455 ASN ASN A . n A 1 456 TYR 456 456 456 TYR TYR A . n A 1 457 THR 457 457 457 THR THR A . n A 1 458 LYS 458 458 458 LYS LYS A . n A 1 459 ALA 459 459 459 ALA ALA A . n A 1 460 GLU 460 460 460 GLU GLU A . n A 1 461 GLU 461 461 461 GLU GLU A . n A 1 462 ILE 462 462 462 ILE ILE A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 SER 464 464 464 SER SER A . n A 1 465 ARG 465 465 465 ARG ARG A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 ILE 467 467 467 ILE ILE A . n A 1 468 VAL 468 468 468 VAL VAL A . n A 1 469 LYS 469 469 469 LYS LYS A . n A 1 470 ARG 470 470 470 ARG ARG A . n A 1 471 TRP 471 471 471 TRP TRP A . n A 1 472 ALA 472 472 472 ALA ALA A . n A 1 473 ASN 473 473 473 ASN ASN A . n A 1 474 PHE 474 474 474 PHE PHE A . n A 1 475 ALA 475 475 475 ALA ALA A . n A 1 476 LYS 476 476 476 LYS LYS A . n A 1 477 TYR 477 477 477 TYR TYR A . n A 1 478 GLY 478 478 478 GLY GLY A . n A 1 479 ASN 479 479 479 ASN ASN A . n A 1 480 PRO 480 480 480 PRO PRO A . n A 1 481 GLN 481 481 481 GLN GLN A . n A 1 482 GLU 482 482 482 GLU GLU A . n A 1 483 THR 483 483 483 THR THR A . n A 1 484 GLN 484 484 484 GLN GLN A . n A 1 485 ASN 485 485 485 ASN ASN A . n A 1 486 ASN 486 486 486 ASN ASN A . n A 1 487 SER 487 487 487 SER SER A . n A 1 488 THR 488 488 488 THR THR A . n A 1 489 SER 489 489 489 SER SER A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 PRO 491 491 491 PRO PRO A . n A 1 492 VAL 492 492 492 VAL VAL A . n A 1 493 PHE 493 493 493 PHE PHE A . n A 1 494 LYS 494 494 494 LYS LYS A . n A 1 495 SER 495 495 495 SER SER A . n A 1 496 THR 496 496 496 THR THR A . n A 1 497 GLU 497 497 497 GLU GLU A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 LYS 499 499 499 LYS LYS A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 LEU 501 501 501 LEU LEU A . n A 1 502 THR 502 502 502 THR THR A . n A 1 503 LEU 503 503 503 LEU LEU A . n A 1 504 ASN 504 504 504 ASN ASN A . n A 1 505 THR 505 505 505 THR THR A . n A 1 506 GLU 506 506 506 GLU GLU A . n A 1 507 SER 507 507 507 SER SER A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ARG 509 509 509 ARG ARG A . n A 1 510 ILE 510 510 510 ILE ILE A . n A 1 511 MET 511 511 511 MET MET A . n A 1 512 THR 512 512 512 THR THR A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 LEU 514 514 514 LEU LEU A . n A 1 515 ARG 515 515 515 ARG ARG A . n A 1 516 ALA 516 516 516 ALA ALA A . n A 1 517 GLN 517 517 517 GLN GLN A . n A 1 518 GLN 518 518 518 GLN GLN A . n A 1 519 CYS 519 519 519 CYS CYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 TRP 522 522 522 TRP TRP A . n A 1 523 THR 523 523 523 THR THR A . n A 1 524 SER 524 524 524 SER SER A . n A 1 525 PHE 525 525 525 PHE PHE A . n A 1 526 PHE 526 526 526 PHE PHE A . n A 1 527 PRO 527 527 527 PRO PRO A . n A 1 528 LYS 528 528 528 LYS LYS A . n A 1 529 VAL 529 529 529 VAL VAL A . n B 1 1 GLU 1 1 ? ? ? B . n B 1 2 ASP 2 2 ? ? ? B . n B 1 3 ASP 3 3 ? ? ? B . n B 1 4 ILE 4 4 4 ILE ILE B . n B 1 5 ILE 5 5 5 ILE ILE B . n B 1 6 ILE 6 6 6 ILE ILE B . n B 1 7 ALA 7 7 7 ALA ALA B . n B 1 8 THR 8 8 8 THR THR B . n B 1 9 LYS 9 9 9 LYS LYS B . n B 1 10 ASN 10 10 10 ASN ASN B . n B 1 11 GLY 11 11 11 GLY GLY B . n B 1 12 LYS 12 12 12 LYS LYS B . n B 1 13 VAL 13 13 13 VAL VAL B . n B 1 14 ARG 14 14 14 ARG ARG B . n B 1 15 GLY 15 15 15 GLY GLY B . n B 1 16 MET 16 16 16 MET MET B . n B 1 17 GLN 17 17 17 GLN GLN B . n B 1 18 LEU 18 18 18 LEU LEU B . n B 1 19 THR 19 19 19 THR THR B . n B 1 20 VAL 20 20 20 VAL VAL B . n B 1 21 PHE 21 21 21 PHE PHE B . n B 1 22 GLY 22 22 22 GLY GLY B . n B 1 23 GLY 23 23 23 GLY GLY B . n B 1 24 THR 24 24 24 THR THR B . n B 1 25 VAL 25 25 25 VAL VAL B . n B 1 26 THR 26 26 26 THR THR B . n B 1 27 ALA 27 27 27 ALA ALA B . n B 1 28 PHE 28 28 28 PHE PHE B . n B 1 29 LEU 29 29 29 LEU LEU B . n B 1 30 GLY 30 30 30 GLY GLY B . n B 1 31 ILE 31 31 31 ILE ILE B . n B 1 32 PRO 32 32 32 PRO PRO B . n B 1 33 TYR 33 33 33 TYR TYR B . n B 1 34 ALA 34 34 34 ALA ALA B . n B 1 35 GLN 35 35 35 GLN GLN B . n B 1 36 PRO 36 36 36 PRO PRO B . n B 1 37 PRO 37 37 37 PRO PRO B . n B 1 38 LEU 38 38 38 LEU LEU B . n B 1 39 GLY 39 39 39 GLY GLY B . n B 1 40 ARG 40 40 40 ARG ARG B . n B 1 41 LEU 41 41 41 LEU LEU B . n B 1 42 ARG 42 42 42 ARG ARG B . n B 1 43 PHE 43 43 43 PHE PHE B . n B 1 44 LYS 44 44 44 LYS LYS B . n B 1 45 LYS 45 45 45 LYS LYS B . n B 1 46 PRO 46 46 46 PRO PRO B . n B 1 47 GLN 47 47 47 GLN GLN B . n B 1 48 SER 48 48 48 SER SER B . n B 1 49 LEU 49 49 49 LEU LEU B . n B 1 50 THR 50 50 50 THR THR B . n B 1 51 LYS 51 51 51 LYS LYS B . n B 1 52 TRP 52 52 52 TRP TRP B . n B 1 53 SER 53 53 53 SER SER B . n B 1 54 ASP 54 54 54 ASP ASP B . n B 1 55 ILE 55 55 55 ILE ILE B . n B 1 56 TRP 56 56 56 TRP TRP B . n B 1 57 ASN 57 57 57 ASN ASN B . n B 1 58 ALA 58 58 58 ALA ALA B . n B 1 59 THR 59 59 59 THR THR B . n B 1 60 LYS 60 60 60 LYS LYS B . n B 1 61 TYR 61 61 61 TYR TYR B . n B 1 62 ALA 62 62 62 ALA ALA B . n B 1 63 ASN 63 63 63 ASN ASN B . n B 1 64 SER 64 64 64 SER SER B . n B 1 65 CYS 65 65 65 CYS CYS B . n B 1 66 CYS 66 66 66 CYS CYS B . n B 1 67 GLN 67 67 67 GLN GLN B . n B 1 68 ASN 68 68 68 ASN ASN B . n B 1 69 ILE 69 69 69 ILE ILE B . n B 1 70 ASP 70 70 70 ASP ASP B . n B 1 71 GLN 71 71 71 GLN GLN B . n B 1 72 SER 72 72 72 SER SER B . n B 1 73 PHE 73 73 73 PHE PHE B . n B 1 74 PRO 74 74 74 PRO PRO B . n B 1 75 GLY 75 75 75 GLY GLY B . n B 1 76 PHE 76 76 76 PHE PHE B . n B 1 77 HIS 77 77 77 HIS HIS B . n B 1 78 GLY 78 78 78 GLY GLY B . n B 1 79 SER 79 79 79 SER SER B . n B 1 80 GLU 80 80 80 GLU GLU B . n B 1 81 MET 81 81 81 MET MET B . n B 1 82 TRP 82 82 82 TRP TRP B . n B 1 83 ASN 83 83 83 ASN ASN B . n B 1 84 PRO 84 84 84 PRO PRO B . n B 1 85 ASN 85 85 85 ASN ASN B . n B 1 86 THR 86 86 86 THR THR B . n B 1 87 ASP 87 87 87 ASP ASP B . n B 1 88 LEU 88 88 88 LEU LEU B . n B 1 89 SER 89 89 89 SER SER B . n B 1 90 GLU 90 90 90 GLU GLU B . n B 1 91 ASP 91 91 91 ASP ASP B . n B 1 92 CYS 92 92 92 CYS CYS B . n B 1 93 LEU 93 93 93 LEU LEU B . n B 1 94 TYR 94 94 94 TYR TYR B . n B 1 95 LEU 95 95 95 LEU LEU B . n B 1 96 ASN 96 96 96 ASN ASN B . n B 1 97 VAL 97 97 97 VAL VAL B . n B 1 98 TRP 98 98 98 TRP TRP B . n B 1 99 ILE 99 99 99 ILE ILE B . n B 1 100 PRO 100 100 100 PRO PRO B . n B 1 101 ALA 101 101 101 ALA ALA B . n B 1 102 PRO 102 102 102 PRO PRO B . n B 1 103 LYS 103 103 103 LYS LYS B . n B 1 104 PRO 104 104 104 PRO PRO B . n B 1 105 LYS 105 105 105 LYS LYS B . n B 1 106 ASN 106 106 106 ASN ASN B . n B 1 107 ALA 107 107 107 ALA ALA B . n B 1 108 THR 108 108 108 THR THR B . n B 1 109 VAL 109 109 109 VAL VAL B . n B 1 110 LEU 110 110 110 LEU LEU B . n B 1 111 ILE 111 111 111 ILE ILE B . n B 1 112 TRP 112 112 112 TRP TRP B . n B 1 113 ILE 113 113 113 ILE ILE B . n B 1 114 TYR 114 114 114 TYR TYR B . n B 1 115 GLY 115 115 115 GLY GLY B . n B 1 116 GLY 116 116 116 GLY GLY B . n B 1 117 GLY 117 117 117 GLY GLY B . n B 1 118 PHE 118 118 118 PHE PHE B . n B 1 119 GLN 119 119 119 GLN GLN B . n B 1 120 THR 120 120 120 THR THR B . n B 1 121 GLY 121 121 121 GLY GLY B . n B 1 122 THR 122 122 122 THR THR B . n B 1 123 SER 123 123 123 SER SER B . n B 1 124 SER 124 124 124 SER SER B . n B 1 125 LEU 125 125 125 LEU LEU B . n B 1 126 HIS 126 126 126 HIS HIS B . n B 1 127 VAL 127 127 127 VAL VAL B . n B 1 128 TYR 128 128 128 TYR TYR B . n B 1 129 ASP 129 129 129 ASP ASP B . n B 1 130 GLY 130 130 130 GLY GLY B . n B 1 131 LYS 131 131 131 LYS LYS B . n B 1 132 PHE 132 132 132 PHE PHE B . n B 1 133 LEU 133 133 133 LEU LEU B . n B 1 134 ALA 134 134 134 ALA ALA B . n B 1 135 ARG 135 135 135 ARG ARG B . n B 1 136 VAL 136 136 136 VAL VAL B . n B 1 137 GLU 137 137 137 GLU GLU B . n B 1 138 ARG 138 138 138 ARG ARG B . n B 1 139 VAL 139 139 139 VAL VAL B . n B 1 140 ILE 140 140 140 ILE ILE B . n B 1 141 VAL 141 141 141 VAL VAL B . n B 1 142 VAL 142 142 142 VAL VAL B . n B 1 143 SER 143 143 143 SER SER B . n B 1 144 MET 144 144 144 MET MET B . n B 1 145 ASN 145 145 145 ASN ASN B . n B 1 146 TYR 146 146 146 TYR TYR B . n B 1 147 ARG 147 147 147 ARG ARG B . n B 1 148 VAL 148 148 148 VAL VAL B . n B 1 149 GLY 149 149 149 GLY GLY B . n B 1 150 ALA 150 150 150 ALA ALA B . n B 1 151 LEU 151 151 151 LEU LEU B . n B 1 152 GLY 152 152 152 GLY GLY B . n B 1 153 PHE 153 153 153 PHE PHE B . n B 1 154 LEU 154 154 154 LEU LEU B . n B 1 155 ALA 155 155 155 ALA ALA B . n B 1 156 LEU 156 156 156 LEU LEU B . n B 1 157 PRO 157 157 157 PRO PRO B . n B 1 158 GLY 158 158 158 GLY GLY B . n B 1 159 ASN 159 159 159 ASN ASN B . n B 1 160 PRO 160 160 160 PRO PRO B . n B 1 161 GLU 161 161 161 GLU GLU B . n B 1 162 ALA 162 162 162 ALA ALA B . n B 1 163 PRO 163 163 163 PRO PRO B . n B 1 164 GLY 164 164 164 GLY GLY B . n B 1 165 ASN 165 165 165 ASN ASN B . n B 1 166 MET 166 166 166 MET MET B . n B 1 167 GLY 167 167 167 GLY GLY B . n B 1 168 LEU 168 168 168 LEU LEU B . n B 1 169 PHE 169 169 169 PHE PHE B . n B 1 170 ASP 170 170 170 ASP ASP B . n B 1 171 GLN 171 171 171 GLN GLN B . n B 1 172 GLN 172 172 172 GLN GLN B . n B 1 173 LEU 173 173 173 LEU LEU B . n B 1 174 ALA 174 174 174 ALA ALA B . n B 1 175 LEU 175 175 175 LEU LEU B . n B 1 176 GLN 176 176 176 GLN GLN B . n B 1 177 TRP 177 177 177 TRP TRP B . n B 1 178 VAL 178 178 178 VAL VAL B . n B 1 179 GLN 179 179 179 GLN GLN B . n B 1 180 LYS 180 180 180 LYS LYS B . n B 1 181 ASN 181 181 181 ASN ASN B . n B 1 182 ILE 182 182 182 ILE ILE B . n B 1 183 ALA 183 183 183 ALA ALA B . n B 1 184 ALA 184 184 184 ALA ALA B . n B 1 185 PHE 185 185 185 PHE PHE B . n B 1 186 GLY 186 186 186 GLY GLY B . n B 1 187 GLY 187 187 187 GLY GLY B . n B 1 188 ASN 188 188 188 ASN ASN B . n B 1 189 PRO 189 189 189 PRO PRO B . n B 1 190 LYS 190 190 190 LYS LYS B . n B 1 191 SER 191 191 191 SER SER B . n B 1 192 VAL 192 192 192 VAL VAL B . n B 1 193 THR 193 193 193 THR THR B . n B 1 194 LEU 194 194 194 LEU LEU B . n B 1 195 PHE 195 195 195 PHE PHE B . n B 1 196 GLY 196 196 196 GLY GLY B . n B 1 197 GLU 197 197 197 GLU GLU B . n B 1 198 SER 198 198 198 SER SER B . n B 1 199 ALA 199 199 199 ALA ALA B . n B 1 200 GLY 200 200 200 GLY GLY B . n B 1 201 ALA 201 201 201 ALA ALA B . n B 1 202 ALA 202 202 202 ALA ALA B . n B 1 203 SER 203 203 203 SER SER B . n B 1 204 VAL 204 204 204 VAL VAL B . n B 1 205 SER 205 205 205 SER SER B . n B 1 206 LEU 206 206 206 LEU LEU B . n B 1 207 HIS 207 207 207 HIS HIS B . n B 1 208 LEU 208 208 208 LEU LEU B . n B 1 209 LEU 209 209 209 LEU LEU B . n B 1 210 SER 210 210 210 SER SER B . n B 1 211 PRO 211 211 211 PRO PRO B . n B 1 212 GLY 212 212 212 GLY GLY B . n B 1 213 SER 213 213 213 SER SER B . n B 1 214 HIS 214 214 214 HIS HIS B . n B 1 215 SER 215 215 215 SER SER B . n B 1 216 LEU 216 216 216 LEU LEU B . n B 1 217 PHE 217 217 217 PHE PHE B . n B 1 218 THR 218 218 218 THR THR B . n B 1 219 ARG 219 219 219 ARG ARG B . n B 1 220 ALA 220 220 220 ALA ALA B . n B 1 221 ILE 221 221 221 ILE ILE B . n B 1 222 LEU 222 222 222 LEU LEU B . n B 1 223 GLN 223 223 223 GLN GLN B . n B 1 224 SER 224 224 224 SER SER B . n B 1 225 GLY 225 225 225 GLY GLY B . n B 1 226 SER 226 226 226 SER SER B . n B 1 227 PHE 227 227 227 PHE PHE B . n B 1 228 ASN 228 228 228 ASN ASN B . n B 1 229 ALA 229 229 229 ALA ALA B . n B 1 230 PRO 230 230 230 PRO PRO B . n B 1 231 TRP 231 231 231 TRP TRP B . n B 1 232 ALA 232 232 232 ALA ALA B . n B 1 233 VAL 233 233 233 VAL VAL B . n B 1 234 THR 234 234 234 THR THR B . n B 1 235 SER 235 235 235 SER SER B . n B 1 236 LEU 236 236 236 LEU LEU B . n B 1 237 TYR 237 237 237 TYR TYR B . n B 1 238 GLU 238 238 238 GLU GLU B . n B 1 239 ALA 239 239 239 ALA ALA B . n B 1 240 ARG 240 240 240 ARG ARG B . n B 1 241 ASN 241 241 241 ASN ASN B . n B 1 242 ARG 242 242 242 ARG ARG B . n B 1 243 THR 243 243 243 THR THR B . n B 1 244 LEU 244 244 244 LEU LEU B . n B 1 245 ASN 245 245 245 ASN ASN B . n B 1 246 LEU 246 246 246 LEU LEU B . n B 1 247 ALA 247 247 247 ALA ALA B . n B 1 248 LYS 248 248 248 LYS LYS B . n B 1 249 LEU 249 249 249 LEU LEU B . n B 1 250 THR 250 250 250 THR THR B . n B 1 251 GLY 251 251 251 GLY GLY B . n B 1 252 CYS 252 252 252 CYS CYS B . n B 1 253 SER 253 253 253 SER SER B . n B 1 254 ARG 254 254 254 ARG ARG B . n B 1 255 GLU 255 255 255 GLU GLU B . n B 1 256 ASN 256 256 256 ASN ASN B . n B 1 257 GLU 257 257 257 GLU GLU B . n B 1 258 THR 258 258 258 THR THR B . n B 1 259 GLU 259 259 259 GLU GLU B . n B 1 260 ILE 260 260 260 ILE ILE B . n B 1 261 ILE 261 261 261 ILE ILE B . n B 1 262 LYS 262 262 262 LYS LYS B . n B 1 263 CYS 263 263 263 CYS CYS B . n B 1 264 LEU 264 264 264 LEU LEU B . n B 1 265 ARG 265 265 265 ARG ARG B . n B 1 266 ASN 266 266 266 ASN ASN B . n B 1 267 LYS 267 267 267 LYS LYS B . n B 1 268 ASP 268 268 268 ASP ASP B . n B 1 269 PRO 269 269 269 PRO PRO B . n B 1 270 GLN 270 270 270 GLN GLN B . n B 1 271 GLU 271 271 271 GLU GLU B . n B 1 272 ILE 272 272 272 ILE ILE B . n B 1 273 LEU 273 273 273 LEU LEU B . n B 1 274 LEU 274 274 274 LEU LEU B . n B 1 275 ASN 275 275 275 ASN ASN B . n B 1 276 GLU 276 276 276 GLU GLU B . n B 1 277 ALA 277 277 277 ALA ALA B . n B 1 278 PHE 278 278 278 PHE PHE B . n B 1 279 VAL 279 279 279 VAL VAL B . n B 1 280 VAL 280 280 280 VAL VAL B . n B 1 281 PRO 281 281 281 PRO PRO B . n B 1 282 TYR 282 282 282 TYR TYR B . n B 1 283 GLY 283 283 283 GLY GLY B . n B 1 284 THR 284 284 284 THR THR B . n B 1 285 PRO 285 285 285 PRO PRO B . n B 1 286 LEU 286 286 286 LEU LEU B . n B 1 287 SER 287 287 287 SER SER B . n B 1 288 VAL 288 288 288 VAL VAL B . n B 1 289 ASN 289 289 289 ASN ASN B . n B 1 290 PHE 290 290 290 PHE PHE B . n B 1 291 GLY 291 291 291 GLY GLY B . n B 1 292 PRO 292 292 292 PRO PRO B . n B 1 293 THR 293 293 293 THR THR B . n B 1 294 VAL 294 294 294 VAL VAL B . n B 1 295 ASP 295 295 295 ASP ASP B . n B 1 296 GLY 296 296 296 GLY GLY B . n B 1 297 ASP 297 297 297 ASP ASP B . n B 1 298 PHE 298 298 298 PHE PHE B . n B 1 299 LEU 299 299 299 LEU LEU B . n B 1 300 THR 300 300 300 THR THR B . n B 1 301 ASP 301 301 301 ASP ASP B . n B 1 302 MET 302 302 302 MET MET B . n B 1 303 PRO 303 303 303 PRO PRO B . n B 1 304 ASP 304 304 304 ASP ASP B . n B 1 305 ILE 305 305 305 ILE ILE B . n B 1 306 LEU 306 306 306 LEU LEU B . n B 1 307 LEU 307 307 307 LEU LEU B . n B 1 308 GLU 308 308 308 GLU GLU B . n B 1 309 LEU 309 309 309 LEU LEU B . n B 1 310 GLY 310 310 310 GLY GLY B . n B 1 311 GLN 311 311 311 GLN GLN B . n B 1 312 PHE 312 312 312 PHE PHE B . n B 1 313 LYS 313 313 313 LYS LYS B . n B 1 314 LYS 314 314 314 LYS LYS B . n B 1 315 THR 315 315 315 THR THR B . n B 1 316 GLN 316 316 316 GLN GLN B . n B 1 317 ILE 317 317 317 ILE ILE B . n B 1 318 LEU 318 318 318 LEU LEU B . n B 1 319 VAL 319 319 319 VAL VAL B . n B 1 320 GLY 320 320 320 GLY GLY B . n B 1 321 VAL 321 321 321 VAL VAL B . n B 1 322 ASN 322 322 322 ASN ASN B . n B 1 323 LYS 323 323 323 LYS LYS B . n B 1 324 ASP 324 324 324 ASP ASP B . n B 1 325 GLU 325 325 325 GLU GLU B . n B 1 326 GLY 326 326 326 GLY GLY B . n B 1 327 THR 327 327 327 THR THR B . n B 1 328 ALA 328 328 328 ALA ALA B . n B 1 329 PHE 329 329 329 PHE PHE B . n B 1 330 LEU 330 330 330 LEU LEU B . n B 1 331 VAL 331 331 331 VAL VAL B . n B 1 332 TYR 332 332 332 TYR TYR B . n B 1 333 GLY 333 333 333 GLY GLY B . n B 1 334 ALA 334 334 334 ALA ALA B . n B 1 335 PRO 335 335 335 PRO PRO B . n B 1 336 GLY 336 336 336 GLY GLY B . n B 1 337 PHE 337 337 337 PHE PHE B . n B 1 338 SER 338 338 338 SER SER B . n B 1 339 LYS 339 339 339 LYS LYS B . n B 1 340 ASP 340 340 340 ASP ASP B . n B 1 341 ASN 341 341 341 ASN ASN B . n B 1 342 ASN 342 342 342 ASN ASN B . n B 1 343 SER 343 343 343 SER SER B . n B 1 344 ILE 344 344 344 ILE ILE B . n B 1 345 ILE 345 345 345 ILE ILE B . n B 1 346 THR 346 346 346 THR THR B . n B 1 347 ARG 347 347 347 ARG ARG B . n B 1 348 LYS 348 348 348 LYS LYS B . n B 1 349 GLU 349 349 349 GLU GLU B . n B 1 350 PHE 350 350 350 PHE PHE B . n B 1 351 GLN 351 351 351 GLN GLN B . n B 1 352 GLU 352 352 352 GLU GLU B . n B 1 353 GLY 353 353 353 GLY GLY B . n B 1 354 LEU 354 354 354 LEU LEU B . n B 1 355 LYS 355 355 355 LYS LYS B . n B 1 356 ILE 356 356 356 ILE ILE B . n B 1 357 PHE 357 357 357 PHE PHE B . n B 1 358 PHE 358 358 358 PHE PHE B . n B 1 359 PRO 359 359 359 PRO PRO B . n B 1 360 GLY 360 360 360 GLY GLY B . n B 1 361 VAL 361 361 361 VAL VAL B . n B 1 362 SER 362 362 362 SER SER B . n B 1 363 GLU 363 363 363 GLU GLU B . n B 1 364 PHE 364 364 364 PHE PHE B . n B 1 365 GLY 365 365 365 GLY GLY B . n B 1 366 LYS 366 366 366 LYS LYS B . n B 1 367 GLU 367 367 367 GLU GLU B . n B 1 368 SER 368 368 368 SER SER B . n B 1 369 ILE 369 369 369 ILE ILE B . n B 1 370 LEU 370 370 370 LEU LEU B . n B 1 371 PHE 371 371 371 PHE PHE B . n B 1 372 HIS 372 372 372 HIS HIS B . n B 1 373 TYR 373 373 373 TYR TYR B . n B 1 374 THR 374 374 374 THR THR B . n B 1 375 ASP 375 375 375 ASP ASP B . n B 1 376 TRP 376 376 376 TRP TRP B . n B 1 377 VAL 377 377 377 VAL VAL B . n B 1 378 ASP 378 378 ? ? ? B . n B 1 379 ASP 379 379 ? ? ? B . n B 1 380 GLN 380 380 380 GLN GLN B . n B 1 381 ARG 381 381 381 ARG ARG B . n B 1 382 PRO 382 382 382 PRO PRO B . n B 1 383 GLU 383 383 383 GLU GLU B . n B 1 384 ASN 384 384 384 ASN ASN B . n B 1 385 TYR 385 385 385 TYR TYR B . n B 1 386 ARG 386 386 386 ARG ARG B . n B 1 387 GLU 387 387 387 GLU GLU B . n B 1 388 ALA 388 388 388 ALA ALA B . n B 1 389 LEU 389 389 389 LEU LEU B . n B 1 390 GLY 390 390 390 GLY GLY B . n B 1 391 ASP 391 391 391 ASP ASP B . n B 1 392 VAL 392 392 392 VAL VAL B . n B 1 393 VAL 393 393 393 VAL VAL B . n B 1 394 GLY 394 394 394 GLY GLY B . n B 1 395 ASP 395 395 395 ASP ASP B . n B 1 396 TYR 396 396 396 TYR TYR B . n B 1 397 ASN 397 397 397 ASN ASN B . n B 1 398 PHE 398 398 398 PHE PHE B . n B 1 399 ILE 399 399 399 ILE ILE B . n B 1 400 CYS 400 400 400 CYS CYS B . n B 1 401 PRO 401 401 401 PRO PRO B . n B 1 402 ALA 402 402 402 ALA ALA B . n B 1 403 LEU 403 403 403 LEU LEU B . n B 1 404 GLU 404 404 404 GLU GLU B . n B 1 405 PHE 405 405 405 PHE PHE B . n B 1 406 THR 406 406 406 THR THR B . n B 1 407 LYS 407 407 407 LYS LYS B . n B 1 408 LYS 408 408 408 LYS LYS B . n B 1 409 PHE 409 409 409 PHE PHE B . n B 1 410 SER 410 410 410 SER SER B . n B 1 411 GLU 411 411 411 GLU GLU B . n B 1 412 TRP 412 412 412 TRP TRP B . n B 1 413 GLY 413 413 413 GLY GLY B . n B 1 414 ASN 414 414 414 ASN ASN B . n B 1 415 ASN 415 415 415 ASN ASN B . n B 1 416 ALA 416 416 416 ALA ALA B . n B 1 417 PHE 417 417 417 PHE PHE B . n B 1 418 PHE 418 418 418 PHE PHE B . n B 1 419 TYR 419 419 419 TYR TYR B . n B 1 420 TYR 420 420 420 TYR TYR B . n B 1 421 PHE 421 421 421 PHE PHE B . n B 1 422 GLU 422 422 422 GLU GLU B . n B 1 423 HIS 423 423 423 HIS HIS B . n B 1 424 ARG 424 424 424 ARG ARG B . n B 1 425 SER 425 425 425 SER SER B . n B 1 426 SER 426 426 426 SER SER B . n B 1 427 LYS 427 427 427 LYS LYS B . n B 1 428 LEU 428 428 428 LEU LEU B . n B 1 429 PRO 429 429 429 PRO PRO B . n B 1 430 TRP 430 430 430 TRP TRP B . n B 1 431 PRO 431 431 431 PRO PRO B . n B 1 432 GLU 432 432 432 GLU GLU B . n B 1 433 TRP 433 433 433 TRP TRP B . n B 1 434 MET 434 434 434 MET MET B . n B 1 435 GLY 435 435 435 GLY GLY B . n B 1 436 VAL 436 436 436 VAL VAL B . n B 1 437 MET 437 437 437 MET MET B . n B 1 438 HIS 438 438 438 HIS HIS B . n B 1 439 GLY 439 439 439 GLY GLY B . n B 1 440 TYR 440 440 440 TYR TYR B . n B 1 441 GLU 441 441 441 GLU GLU B . n B 1 442 ILE 442 442 442 ILE ILE B . n B 1 443 GLU 443 443 443 GLU GLU B . n B 1 444 PHE 444 444 444 PHE PHE B . n B 1 445 VAL 445 445 445 VAL VAL B . n B 1 446 PHE 446 446 446 PHE PHE B . n B 1 447 GLY 447 447 447 GLY GLY B . n B 1 448 LEU 448 448 448 LEU LEU B . n B 1 449 PRO 449 449 449 PRO PRO B . n B 1 450 LEU 450 450 450 LEU LEU B . n B 1 451 GLU 451 451 451 GLU GLU B . n B 1 452 ARG 452 452 452 ARG ARG B . n B 1 453 ARG 453 453 453 ARG ARG B . n B 1 454 ASP 454 454 454 ASP ASP B . n B 1 455 ASN 455 455 455 ASN ASN B . n B 1 456 TYR 456 456 456 TYR TYR B . n B 1 457 THR 457 457 457 THR THR B . n B 1 458 LYS 458 458 458 LYS LYS B . n B 1 459 ALA 459 459 459 ALA ALA B . n B 1 460 GLU 460 460 460 GLU GLU B . n B 1 461 GLU 461 461 461 GLU GLU B . n B 1 462 ILE 462 462 462 ILE ILE B . n B 1 463 LEU 463 463 463 LEU LEU B . n B 1 464 SER 464 464 464 SER SER B . n B 1 465 ARG 465 465 465 ARG ARG B . n B 1 466 SER 466 466 466 SER SER B . n B 1 467 ILE 467 467 467 ILE ILE B . n B 1 468 VAL 468 468 468 VAL VAL B . n B 1 469 LYS 469 469 469 LYS LYS B . n B 1 470 ARG 470 470 470 ARG ARG B . n B 1 471 TRP 471 471 471 TRP TRP B . n B 1 472 ALA 472 472 472 ALA ALA B . n B 1 473 ASN 473 473 473 ASN ASN B . n B 1 474 PHE 474 474 474 PHE PHE B . n B 1 475 ALA 475 475 475 ALA ALA B . n B 1 476 LYS 476 476 476 LYS LYS B . n B 1 477 TYR 477 477 477 TYR TYR B . n B 1 478 GLY 478 478 478 GLY GLY B . n B 1 479 ASN 479 479 479 ASN ASN B . n B 1 480 PRO 480 480 480 PRO PRO B . n B 1 481 GLN 481 481 481 GLN GLN B . n B 1 482 GLU 482 482 482 GLU GLU B . n B 1 483 THR 483 483 483 THR THR B . n B 1 484 GLN 484 484 484 GLN GLN B . n B 1 485 ASN 485 485 485 ASN ASN B . n B 1 486 ASN 486 486 486 ASN ASN B . n B 1 487 SER 487 487 487 SER SER B . n B 1 488 THR 488 488 488 THR THR B . n B 1 489 SER 489 489 489 SER SER B . n B 1 490 TRP 490 490 490 TRP TRP B . n B 1 491 PRO 491 491 491 PRO PRO B . n B 1 492 VAL 492 492 492 VAL VAL B . n B 1 493 PHE 493 493 493 PHE PHE B . n B 1 494 LYS 494 494 494 LYS LYS B . n B 1 495 SER 495 495 495 SER SER B . n B 1 496 THR 496 496 496 THR THR B . n B 1 497 GLU 497 497 497 GLU GLU B . n B 1 498 GLN 498 498 498 GLN GLN B . n B 1 499 LYS 499 499 499 LYS LYS B . n B 1 500 TYR 500 500 500 TYR TYR B . n B 1 501 LEU 501 501 501 LEU LEU B . n B 1 502 THR 502 502 502 THR THR B . n B 1 503 LEU 503 503 503 LEU LEU B . n B 1 504 ASN 504 504 504 ASN ASN B . n B 1 505 THR 505 505 505 THR THR B . n B 1 506 GLU 506 506 506 GLU GLU B . n B 1 507 SER 507 507 507 SER SER B . n B 1 508 THR 508 508 508 THR THR B . n B 1 509 ARG 509 509 509 ARG ARG B . n B 1 510 ILE 510 510 510 ILE ILE B . n B 1 511 MET 511 511 511 MET MET B . n B 1 512 THR 512 512 512 THR THR B . n B 1 513 LYS 513 513 513 LYS LYS B . n B 1 514 LEU 514 514 514 LEU LEU B . n B 1 515 ARG 515 515 515 ARG ARG B . n B 1 516 ALA 516 516 516 ALA ALA B . n B 1 517 GLN 517 517 517 GLN GLN B . n B 1 518 GLN 518 518 518 GLN GLN B . n B 1 519 CYS 519 519 519 CYS CYS B . n B 1 520 ARG 520 520 520 ARG ARG B . n B 1 521 PHE 521 521 521 PHE PHE B . n B 1 522 TRP 522 522 522 TRP TRP B . n B 1 523 THR 523 523 523 THR THR B . n B 1 524 SER 524 524 524 SER SER B . n B 1 525 PHE 525 525 525 PHE PHE B . n B 1 526 PHE 526 526 526 PHE PHE B . n B 1 527 PRO 527 527 527 PRO PRO B . n B 1 528 LYS 528 528 528 LYS LYS B . n B 1 529 VAL 529 529 529 VAL VAL B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 TCX 1 601 600 TCX TCX A . D 3 NAG 1 602 1531 NAG NAG A . E 3 NAG 2 603 1532 NAG NAG A . F 4 FUC 3 604 1533 FUC FUC A . G 3 NAG 1 605 1534 NAG NAG A . H 3 NAG 2 606 1535 NAG NAG A . I 4 FUC 3 607 1536 FUC FUC A . J 3 NAG 1 608 1537 NAG NAG A . K 3 NAG 1 609 1538 NAG NAG A . L 3 NAG 1 610 1539 NAG NAG A . M 5 SO4 1 611 1540 SO4 SO4 A . N 5 SO4 1 612 1541 SO4 SO4 A . O 6 CL 1 613 1542 CL CL A . P 2 TCX 1 601 600 TCX TCX B . Q 3 NAG 1 602 1531 NAG NAG B . R 3 NAG 2 603 1532 NAG NAG B . S 4 FUC 3 604 1533 FUC FUC B . T 3 NAG 1 605 1534 NAG NAG B . U 3 NAG 2 606 1535 NAG NAG B . V 4 FUC 3 607 1536 FUC FUC B . W 3 NAG 1 608 1537 NAG NAG B . X 3 NAG 1 609 1538 NAG NAG B . Y 3 NAG 1 610 1539 NAG NAG B . Z 5 SO4 1 611 1540 SO4 SO4 B . AA 7 HOH 1 701 2041 HOH HOH A . AA 7 HOH 2 702 2002 HOH HOH A . AA 7 HOH 3 703 2034 HOH HOH A . AA 7 HOH 4 704 2016 HOH HOH A . AA 7 HOH 5 705 2028 HOH HOH A . AA 7 HOH 6 706 2017 HOH HOH A . AA 7 HOH 7 707 2053 HOH HOH A . AA 7 HOH 8 708 2054 HOH HOH A . AA 7 HOH 9 709 2023 HOH HOH A . AA 7 HOH 10 710 2027 HOH HOH A . AA 7 HOH 11 711 2046 HOH HOH A . AA 7 HOH 12 712 2007 HOH HOH A . AA 7 HOH 13 713 2024 HOH HOH A . AA 7 HOH 14 714 2038 HOH HOH A . AA 7 HOH 15 715 2065 HOH HOH A . AA 7 HOH 16 716 2014 HOH HOH A . AA 7 HOH 17 717 2013 HOH HOH A . AA 7 HOH 18 718 2036 HOH HOH A . AA 7 HOH 19 719 2025 HOH HOH A . AA 7 HOH 20 720 2044 HOH HOH A . AA 7 HOH 21 721 2055 HOH HOH A . AA 7 HOH 22 722 2004 HOH HOH A . AA 7 HOH 23 723 2047 HOH HOH A . AA 7 HOH 24 724 2063 HOH HOH A . AA 7 HOH 25 725 2033 HOH HOH A . AA 7 HOH 26 726 2049 HOH HOH A . AA 7 HOH 27 727 2064 HOH HOH A . AA 7 HOH 28 728 2008 HOH HOH A . AA 7 HOH 29 729 2056 HOH HOH A . AA 7 HOH 30 730 2040 HOH HOH A . AA 7 HOH 31 731 2060 HOH HOH A . AA 7 HOH 32 732 2051 HOH HOH A . AA 7 HOH 33 733 2018 HOH HOH A . AA 7 HOH 34 734 2015 HOH HOH A . AA 7 HOH 35 735 2011 HOH HOH A . AA 7 HOH 36 736 2019 HOH HOH A . AA 7 HOH 37 737 2005 HOH HOH A . AA 7 HOH 38 738 2037 HOH HOH A . AA 7 HOH 39 739 2058 HOH HOH A . AA 7 HOH 40 740 2062 HOH HOH A . AA 7 HOH 41 741 2029 HOH HOH A . AA 7 HOH 42 742 2059 HOH HOH A . AA 7 HOH 43 743 2052 HOH HOH A . AA 7 HOH 44 744 2061 HOH HOH A . AA 7 HOH 45 745 2050 HOH HOH A . AA 7 HOH 46 746 2045 HOH HOH A . AA 7 HOH 47 747 2042 HOH HOH A . AA 7 HOH 48 748 2035 HOH HOH A . AA 7 HOH 49 749 2031 HOH HOH A . AA 7 HOH 50 750 2043 HOH HOH A . AA 7 HOH 51 751 2006 HOH HOH A . AA 7 HOH 52 752 2030 HOH HOH A . AA 7 HOH 53 753 2026 HOH HOH A . AA 7 HOH 54 754 2032 HOH HOH A . AA 7 HOH 55 755 2039 HOH HOH A . AA 7 HOH 56 756 2057 HOH HOH A . AA 7 HOH 57 757 2009 HOH HOH A . AA 7 HOH 58 758 2012 HOH HOH A . AA 7 HOH 59 759 2010 HOH HOH A . AA 7 HOH 60 760 2021 HOH HOH A . AA 7 HOH 61 761 2048 HOH HOH A . AA 7 HOH 62 762 2022 HOH HOH A . AA 7 HOH 63 763 2001 HOH HOH A . AA 7 HOH 64 764 2003 HOH HOH A . AA 7 HOH 65 765 2020 HOH HOH A . BA 7 HOH 1 701 2047 HOH HOH B . BA 7 HOH 2 702 2027 HOH HOH B . BA 7 HOH 3 703 2008 HOH HOH B . BA 7 HOH 4 704 2033 HOH HOH B . BA 7 HOH 5 705 2031 HOH HOH B . BA 7 HOH 6 706 2023 HOH HOH B . BA 7 HOH 7 707 2013 HOH HOH B . BA 7 HOH 8 708 2024 HOH HOH B . BA 7 HOH 9 709 2052 HOH HOH B . BA 7 HOH 10 710 2011 HOH HOH B . BA 7 HOH 11 711 2068 HOH HOH B . BA 7 HOH 12 712 2066 HOH HOH B . BA 7 HOH 13 713 2025 HOH HOH B . BA 7 HOH 14 714 2016 HOH HOH B . BA 7 HOH 15 715 2039 HOH HOH B . BA 7 HOH 16 716 2049 HOH HOH B . BA 7 HOH 17 717 2041 HOH HOH B . BA 7 HOH 18 718 2002 HOH HOH B . BA 7 HOH 19 719 2054 HOH HOH B . BA 7 HOH 20 720 2055 HOH HOH B . BA 7 HOH 21 721 2014 HOH HOH B . BA 7 HOH 22 722 2043 HOH HOH B . BA 7 HOH 23 723 2063 HOH HOH B . BA 7 HOH 24 724 2064 HOH HOH B . BA 7 HOH 25 725 2062 HOH HOH B . BA 7 HOH 26 726 2036 HOH HOH B . BA 7 HOH 27 727 2045 HOH HOH B . BA 7 HOH 28 728 2053 HOH HOH B . BA 7 HOH 29 729 2019 HOH HOH B . BA 7 HOH 30 730 2021 HOH HOH B . BA 7 HOH 31 731 2028 HOH HOH B . BA 7 HOH 32 732 2017 HOH HOH B . BA 7 HOH 33 733 2034 HOH HOH B . BA 7 HOH 34 734 2004 HOH HOH B . BA 7 HOH 35 735 2007 HOH HOH B . BA 7 HOH 36 736 2070 HOH HOH B . BA 7 HOH 37 737 2030 HOH HOH B . BA 7 HOH 38 738 2061 HOH HOH B . BA 7 HOH 39 739 2048 HOH HOH B . BA 7 HOH 40 740 2038 HOH HOH B . BA 7 HOH 41 741 2042 HOH HOH B . BA 7 HOH 42 742 2071 HOH HOH B . BA 7 HOH 43 743 2059 HOH HOH B . BA 7 HOH 44 744 2010 HOH HOH B . BA 7 HOH 45 745 2060 HOH HOH B . BA 7 HOH 46 746 2006 HOH HOH B . BA 7 HOH 47 747 2035 HOH HOH B . BA 7 HOH 48 748 2040 HOH HOH B . BA 7 HOH 49 749 2058 HOH HOH B . BA 7 HOH 50 750 2015 HOH HOH B . BA 7 HOH 51 751 2026 HOH HOH B . BA 7 HOH 52 752 2001 HOH HOH B . BA 7 HOH 53 753 2022 HOH HOH B . BA 7 HOH 54 754 2051 HOH HOH B . BA 7 HOH 55 755 2072 HOH HOH B . BA 7 HOH 56 756 2020 HOH HOH B . BA 7 HOH 57 757 2056 HOH HOH B . BA 7 HOH 58 758 2018 HOH HOH B . BA 7 HOH 59 759 2037 HOH HOH B . BA 7 HOH 60 760 2046 HOH HOH B . BA 7 HOH 61 761 2067 HOH HOH B . BA 7 HOH 62 762 2005 HOH HOH B . BA 7 HOH 63 763 2069 HOH HOH B . BA 7 HOH 64 764 2003 HOH HOH B . BA 7 HOH 65 765 2050 HOH HOH B . BA 7 HOH 66 766 2057 HOH HOH B . BA 7 HOH 67 767 2032 HOH HOH B . BA 7 HOH 68 768 2044 HOH HOH B . BA 7 HOH 69 769 2065 HOH HOH B . BA 7 HOH 70 770 2009 HOH HOH B . BA 7 HOH 71 771 2029 HOH HOH B . BA 7 HOH 72 772 2012 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 57 A ASN 57 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 106 A ASN 106 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 241 A ASN 241 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 341 A ASN 341 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 485 A ASN 485 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 57 B ASN 57 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 106 B ASN 106 ? ASN 'GLYCOSYLATION SITE' 8 B ASN 241 B ASN 241 ? ASN 'GLYCOSYLATION SITE' 9 B ASN 341 B ASN 341 ? ASN 'GLYCOSYLATION SITE' 10 B ASN 485 B ASN 485 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details octameric _pdbx_struct_assembly.oligomeric_count 8 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2,3,4 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 34890 ? 1 MORE -56.6 ? 1 'SSA (A^2)' 158820 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 2_455 -x-1,-y,z -1.0000000000 0.0000000000 0.0000000000 -150.3500000000 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 3 'crystal symmetry operation' 4_445 y-1/2,-x-1/2,z 0.0000000000 1.0000000000 0.0000000000 -75.1750000000 -1.0000000000 0.0000000000 0.0000000000 -75.1750000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 4 'crystal symmetry operation' 3_455 -y-1/2,x+1/2,z 0.0000000000 -1.0000000000 0.0000000000 -75.1750000000 1.0000000000 0.0000000000 0.0000000000 75.1750000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 # _pdbx_struct_special_symmetry.id 1 _pdbx_struct_special_symmetry.PDB_model_num 1 _pdbx_struct_special_symmetry.auth_asym_id A _pdbx_struct_special_symmetry.auth_comp_id HOH _pdbx_struct_special_symmetry.auth_seq_id 728 _pdbx_struct_special_symmetry.PDB_ins_code ? _pdbx_struct_special_symmetry.label_asym_id AA _pdbx_struct_special_symmetry.label_comp_id HOH _pdbx_struct_special_symmetry.label_seq_id . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2009-05-26 2 'Structure model' 1 1 2011-05-08 3 'Structure model' 1 2 2011-07-13 4 'Structure model' 1 3 2018-02-28 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Version format compliance' 3 4 'Structure model' Advisory 4 4 'Structure model' 'Source and taxonomy' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 4 'Structure model' entity_src_gen 2 4 'Structure model' pdbx_unobs_or_zero_occ_atoms # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 4 'Structure model' '_entity_src_gen.gene_src_common_name' 2 4 'Structure model' '_entity_src_gen.pdbx_gene_src_scientific_name' 3 4 'Structure model' '_entity_src_gen.pdbx_host_org_cell_line' 4 4 'Structure model' '_entity_src_gen.pdbx_host_org_scientific_name' 5 4 'Structure model' '_entity_src_gen.pdbx_host_org_strain' 6 4 'Structure model' '_entity_src_gen.pdbx_host_org_variant' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.4.0069 ? 1 XDS 'data reduction' . ? 2 XSCALE 'data scaling' . ? 3 XDS phasing . ? 4 # _pdbx_entry_details.entry_id 2WIL _pdbx_entry_details.compound_details ;ENGINEERED RESIDUE IN CHAIN A, ASN 45 TO GLN ENGINEERED RESIDUE IN CHAIN A, ASN 509 TO GLN ENGINEERED RESIDUE IN CHAIN B, ASN 45 TO GLN ENGINEERED RESIDUE IN CHAIN B, ASN 509 TO GLN ; _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OE1 A GLN 380 ? ? O A HOH 701 ? ? 2.15 2 1 O B LYS 355 ? ? O B HOH 701 ? ? 2.18 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CB _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 TYR _pdbx_validate_rmsd_bond.auth_seq_id_1 282 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 CG _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 TYR _pdbx_validate_rmsd_bond.auth_seq_id_2 282 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.341 _pdbx_validate_rmsd_bond.bond_target_value 1.512 _pdbx_validate_rmsd_bond.bond_deviation -0.171 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.015 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CB A TYR 282 ? ? CG A TYR 282 ? ? CD2 A TYR 282 ? ? 128.37 121.00 7.37 0.60 N 2 1 CB A TYR 282 ? ? CG A TYR 282 ? ? CD1 A TYR 282 ? ? 113.50 121.00 -7.50 0.60 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 3 ? ? 37.68 104.71 2 1 LYS A 9 ? ? -59.47 5.21 3 1 ASP A 54 ? ? 98.86 -167.35 4 1 ALA A 58 ? ? -104.26 72.72 5 1 GLN A 67 ? ? 178.13 161.25 6 1 CYS A 92 ? ? -146.90 12.32 7 1 LYS A 103 ? ? -35.36 124.72 8 1 PHE A 118 ? ? 57.93 10.51 9 1 PHE A 153 ? ? -141.32 16.89 10 1 SER A 198 ? ? 44.36 -120.62 11 1 HIS A 214 ? A -29.15 -54.35 12 1 SER A 224 ? ? 37.54 68.70 13 1 SER A 226 ? ? -171.59 147.43 14 1 ASN A 228 ? ? -68.89 4.90 15 1 GLU A 255 ? ? -107.14 -63.92 16 1 PRO A 269 ? ? -28.97 -51.79 17 1 ASP A 297 ? ? -113.30 -82.80 18 1 ASP A 301 ? ? 173.86 159.10 19 1 GLN A 311 ? ? -103.17 66.06 20 1 ASN A 342 ? ? -74.21 22.30 21 1 SER A 362 ? ? -34.43 153.11 22 1 THR A 374 ? ? -106.22 44.03 23 1 ASP A 375 ? ? -101.21 79.53 24 1 PHE A 398 ? ? -135.20 -69.00 25 1 VAL A 436 ? ? -63.77 89.28 26 1 PRO A 449 ? ? -66.20 0.12 27 1 ARG A 453 ? ? -64.54 70.83 28 1 ASP A 454 ? ? -152.48 -16.60 29 1 PRO A 480 ? ? -89.35 43.92 30 1 ASN A 485 ? ? -98.43 49.83 31 1 GLU A 506 ? ? -73.93 -107.25 32 1 LYS B 9 ? ? -59.74 6.01 33 1 PHE B 28 ? ? -110.86 79.42 34 1 ASP B 54 ? ? 99.05 -167.48 35 1 ALA B 58 ? ? -103.95 73.38 36 1 GLN B 67 ? ? 176.04 157.59 37 1 MET B 81 ? ? -49.37 -17.95 38 1 LYS B 103 ? ? -33.54 125.47 39 1 SER B 198 ? ? 39.89 -124.57 40 1 SER B 224 ? ? 26.93 77.53 41 1 SER B 226 ? ? -171.84 146.06 42 1 GLU B 255 ? ? -108.19 -67.15 43 1 PRO B 269 ? ? -28.89 -55.62 44 1 PRO B 285 ? ? -47.69 -17.02 45 1 ASP B 297 ? ? -114.69 -77.14 46 1 ASP B 301 ? ? 170.19 160.07 47 1 GLN B 311 ? ? -106.26 66.96 48 1 ASN B 342 ? ? -74.98 22.60 49 1 SER B 362 ? ? -37.37 154.34 50 1 THR B 374 ? ? -106.23 46.63 51 1 ASP B 375 ? ? -102.93 78.36 52 1 PHE B 398 ? ? -132.58 -66.52 53 1 VAL B 436 ? ? -62.03 87.53 54 1 PRO B 449 ? ? -69.86 1.88 55 1 ARG B 453 ? ? -60.18 71.01 56 1 ASP B 454 ? ? -154.69 -15.74 57 1 PRO B 480 ? ? -83.42 41.40 58 1 ASN B 485 ? ? -96.37 46.72 59 1 GLU B 506 ? ? -75.97 -106.69 60 1 ARG B 515 ? ? 37.62 55.75 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ASN 486 ? CG ? A ASN 486 CG 2 1 Y 1 A ASN 486 ? OD1 ? A ASN 486 OD1 3 1 Y 1 A ASN 486 ? ND2 ? A ASN 486 ND2 4 1 Y 1 B ASN 486 ? CG ? B ASN 486 CG 5 1 Y 1 B ASN 486 ? OD1 ? B ASN 486 OD1 6 1 Y 1 B ASN 486 ? ND2 ? B ASN 486 ND2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 1 ? A GLU 1 2 1 Y 1 A ASP 378 ? A ASP 378 3 1 Y 1 A ASP 379 ? A ASP 379 4 1 Y 1 B GLU 1 ? B GLU 1 5 1 Y 1 B ASP 2 ? B ASP 2 6 1 Y 1 B ASP 3 ? B ASP 3 7 1 Y 1 B ASP 378 ? B ASP 378 8 1 Y 1 B ASP 379 ? B ASP 379 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'ethylphosphoramidic acid' TCX 3 N-ACETYL-D-GLUCOSAMINE NAG 4 ALPHA-L-FUCOSE FUC 5 'SULFATE ION' SO4 6 'CHLORIDE ION' CL 7 water HOH #