data_2QFR # _entry.id 2QFR # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2QFR RCSB RCSB043542 WWPDB D_1000043542 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3kbp 'free enzyme' unspecified PDB 4kbp 'phosphate complex' unspecified PDB 2qfp 'fluoride complex' unspecified # _pdbx_database_status.entry_id 2QFR _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2007-06-27 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Guddat, L.W.' 1 'Schenk, G.' 2 'Gahan, L.R.' 3 'Elliot, T.W.' 4 'Leung, E.' 5 # _citation.id primary _citation.title ;Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. ; _citation.journal_abbrev 'Bmc Struct.Biol.' _citation.journal_volume 8 _citation.page_first 6 _citation.page_last 6 _citation.year 2008 _citation.journal_id_ASTM ? _citation.country UK _citation.journal_id_ISSN 1472-6807 _citation.journal_id_CSD ? _citation.book_publisher ? _citation.pdbx_database_id_PubMed 18234116 _citation.pdbx_database_id_DOI 10.1186/1472-6807-8-6 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Schenk, G.' 1 primary 'Elliott, T.W.' 2 primary 'Leung, E.' 3 primary 'Carrington, L.E.' 4 primary 'Mitic, N.' 5 primary 'Gahan, L.R.' 6 primary 'Guddat, L.W.' 7 # _cell.length_a 148.030 _cell.length_b 148.030 _cell.length_c 160.090 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 2QFR _cell.pdbx_unique_axis ? _cell.Z_PDB 16 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'I 41' _symmetry.entry_id 2QFR _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 80 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'Purple acid phosphatase' 49312.117 2 3.1.3.2 ? ? ? 2 non-polymer syn 'FE (III) ION' 55.845 2 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 4 ? ? ? ? 5 non-polymer man '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' 221.208 2 ? ? ? ? 6 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 7 water nat water 18.015 401 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIH HTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYA DRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHII VLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYE RSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQ DGVAVEADSVWFFNRHWYPVDDST ; _entity_poly.pdbx_seq_one_letter_code_can ;RDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIH HTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYA DRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHII VLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYE RSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQ DGVAVEADSVWFFNRHWYPVDDST ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 ASP n 1 3 MET n 1 4 PRO n 1 5 LEU n 1 6 ASP n 1 7 SER n 1 8 ASP n 1 9 VAL n 1 10 PHE n 1 11 ARG n 1 12 VAL n 1 13 PRO n 1 14 PRO n 1 15 GLY n 1 16 TYR n 1 17 ASN n 1 18 ALA n 1 19 PRO n 1 20 GLN n 1 21 GLN n 1 22 VAL n 1 23 HIS n 1 24 ILE n 1 25 THR n 1 26 GLN n 1 27 GLY n 1 28 ASP n 1 29 LEU n 1 30 VAL n 1 31 GLY n 1 32 ARG n 1 33 ALA n 1 34 MET n 1 35 ILE n 1 36 ILE n 1 37 SER n 1 38 TRP n 1 39 VAL n 1 40 THR n 1 41 MET n 1 42 ASP n 1 43 GLU n 1 44 PRO n 1 45 GLY n 1 46 SER n 1 47 SER n 1 48 ALA n 1 49 VAL n 1 50 ARG n 1 51 TYR n 1 52 TRP n 1 53 SER n 1 54 GLU n 1 55 LYS n 1 56 ASN n 1 57 GLY n 1 58 ARG n 1 59 LYS n 1 60 ARG n 1 61 ILE n 1 62 ALA n 1 63 LYS n 1 64 GLY n 1 65 LYS n 1 66 MET n 1 67 SER n 1 68 THR n 1 69 TYR n 1 70 ARG n 1 71 PHE n 1 72 PHE n 1 73 ASN n 1 74 TYR n 1 75 SER n 1 76 SER n 1 77 GLY n 1 78 PHE n 1 79 ILE n 1 80 HIS n 1 81 HIS n 1 82 THR n 1 83 THR n 1 84 ILE n 1 85 ARG n 1 86 LYS n 1 87 LEU n 1 88 LYS n 1 89 TYR n 1 90 ASN n 1 91 THR n 1 92 LYS n 1 93 TYR n 1 94 TYR n 1 95 TYR n 1 96 GLU n 1 97 VAL n 1 98 GLY n 1 99 LEU n 1 100 ARG n 1 101 ASN n 1 102 THR n 1 103 THR n 1 104 ARG n 1 105 ARG n 1 106 PHE n 1 107 SER n 1 108 PHE n 1 109 ILE n 1 110 THR n 1 111 PRO n 1 112 PRO n 1 113 GLN n 1 114 THR n 1 115 GLY n 1 116 LEU n 1 117 ASP n 1 118 VAL n 1 119 PRO n 1 120 TYR n 1 121 THR n 1 122 PHE n 1 123 GLY n 1 124 LEU n 1 125 ILE n 1 126 GLY n 1 127 ASP n 1 128 LEU n 1 129 GLY n 1 130 GLN n 1 131 SER n 1 132 PHE n 1 133 ASP n 1 134 SER n 1 135 ASN n 1 136 THR n 1 137 THR n 1 138 LEU n 1 139 SER n 1 140 HIS n 1 141 TYR n 1 142 GLU n 1 143 LEU n 1 144 SER n 1 145 PRO n 1 146 LYS n 1 147 LYS n 1 148 GLY n 1 149 GLN n 1 150 THR n 1 151 VAL n 1 152 LEU n 1 153 PHE n 1 154 VAL n 1 155 GLY n 1 156 ASP n 1 157 LEU n 1 158 SER n 1 159 TYR n 1 160 ALA n 1 161 ASP n 1 162 ARG n 1 163 TYR n 1 164 PRO n 1 165 ASN n 1 166 HIS n 1 167 ASP n 1 168 ASN n 1 169 VAL n 1 170 ARG n 1 171 TRP n 1 172 ASP n 1 173 THR n 1 174 TRP n 1 175 GLY n 1 176 ARG n 1 177 PHE n 1 178 THR n 1 179 GLU n 1 180 ARG n 1 181 SER n 1 182 VAL n 1 183 ALA n 1 184 TYR n 1 185 GLN n 1 186 PRO n 1 187 TRP n 1 188 ILE n 1 189 TRP n 1 190 THR n 1 191 ALA n 1 192 GLY n 1 193 ASN n 1 194 HIS n 1 195 GLU n 1 196 ILE n 1 197 GLU n 1 198 PHE n 1 199 ALA n 1 200 PRO n 1 201 GLU n 1 202 ILE n 1 203 ASN n 1 204 GLU n 1 205 THR n 1 206 GLU n 1 207 PRO n 1 208 PHE n 1 209 LYS n 1 210 PRO n 1 211 PHE n 1 212 SER n 1 213 TYR n 1 214 ARG n 1 215 TYR n 1 216 HIS n 1 217 VAL n 1 218 PRO n 1 219 TYR n 1 220 GLU n 1 221 ALA n 1 222 SER n 1 223 GLN n 1 224 SER n 1 225 THR n 1 226 SER n 1 227 PRO n 1 228 PHE n 1 229 TRP n 1 230 TYR n 1 231 SER n 1 232 ILE n 1 233 LYS n 1 234 ARG n 1 235 ALA n 1 236 SER n 1 237 ALA n 1 238 HIS n 1 239 ILE n 1 240 ILE n 1 241 VAL n 1 242 LEU n 1 243 SER n 1 244 SER n 1 245 TYR n 1 246 SER n 1 247 ALA n 1 248 TYR n 1 249 GLY n 1 250 ARG n 1 251 GLY n 1 252 THR n 1 253 PRO n 1 254 GLN n 1 255 TYR n 1 256 THR n 1 257 TRP n 1 258 LEU n 1 259 LYS n 1 260 LYS n 1 261 GLU n 1 262 LEU n 1 263 ARG n 1 264 LYS n 1 265 VAL n 1 266 LYS n 1 267 ARG n 1 268 SER n 1 269 GLU n 1 270 THR n 1 271 PRO n 1 272 TRP n 1 273 LEU n 1 274 ILE n 1 275 VAL n 1 276 LEU n 1 277 MET n 1 278 HIS n 1 279 SER n 1 280 PRO n 1 281 LEU n 1 282 TYR n 1 283 ASN n 1 284 SER n 1 285 TYR n 1 286 ASN n 1 287 HIS n 1 288 HIS n 1 289 PHE n 1 290 MET n 1 291 GLU n 1 292 GLY n 1 293 GLU n 1 294 ALA n 1 295 MET n 1 296 ARG n 1 297 THR n 1 298 LYS n 1 299 PHE n 1 300 GLU n 1 301 ALA n 1 302 TRP n 1 303 PHE n 1 304 VAL n 1 305 LYS n 1 306 TYR n 1 307 LYS n 1 308 VAL n 1 309 ASP n 1 310 VAL n 1 311 VAL n 1 312 PHE n 1 313 ALA n 1 314 GLY n 1 315 HIS n 1 316 VAL n 1 317 HIS n 1 318 ALA n 1 319 TYR n 1 320 GLU n 1 321 ARG n 1 322 SER n 1 323 GLU n 1 324 ARG n 1 325 VAL n 1 326 SER n 1 327 ASN n 1 328 ILE n 1 329 ALA n 1 330 TYR n 1 331 LYS n 1 332 ILE n 1 333 THR n 1 334 ASN n 1 335 GLY n 1 336 LEU n 1 337 CYS n 1 338 THR n 1 339 PRO n 1 340 VAL n 1 341 LYS n 1 342 ASP n 1 343 GLN n 1 344 SER n 1 345 ALA n 1 346 PRO n 1 347 VAL n 1 348 TYR n 1 349 ILE n 1 350 THR n 1 351 ILE n 1 352 GLY n 1 353 ASP n 1 354 ALA n 1 355 GLY n 1 356 ASN n 1 357 TYR n 1 358 GLY n 1 359 VAL n 1 360 ILE n 1 361 ASP n 1 362 SER n 1 363 ASN n 1 364 MET n 1 365 ILE n 1 366 GLN n 1 367 PRO n 1 368 GLN n 1 369 PRO n 1 370 GLU n 1 371 TYR n 1 372 SER n 1 373 ALA n 1 374 PHE n 1 375 ARG n 1 376 GLU n 1 377 ALA n 1 378 SER n 1 379 PHE n 1 380 GLY n 1 381 HIS n 1 382 GLY n 1 383 MET n 1 384 PHE n 1 385 ASP n 1 386 ILE n 1 387 LYS n 1 388 ASN n 1 389 ARG n 1 390 THR n 1 391 HIS n 1 392 ALA n 1 393 HIS n 1 394 PHE n 1 395 SER n 1 396 TRP n 1 397 ASN n 1 398 ARG n 1 399 ASN n 1 400 GLN n 1 401 ASP n 1 402 GLY n 1 403 VAL n 1 404 ALA n 1 405 VAL n 1 406 GLU n 1 407 ALA n 1 408 ASP n 1 409 SER n 1 410 VAL n 1 411 TRP n 1 412 PHE n 1 413 PHE n 1 414 ASN n 1 415 ARG n 1 416 HIS n 1 417 TRP n 1 418 TYR n 1 419 PRO n 1 420 VAL n 1 421 ASP n 1 422 ASP n 1 423 SER n 1 424 THR n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'Kidney bean' _entity_src_nat.pdbx_organism_scientific 'Phaseolus vulgaris' _entity_src_nat.pdbx_ncbi_taxonomy_id 3885 _entity_src_nat.genus ? _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code O24319_PHAVU _struct_ref.pdbx_db_accession O24319 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;RDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIH HTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYA DRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHII VLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYE RSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQ DGVAVEADSVWFFNRHWYPVDDST ; _struct_ref.pdbx_align_begin 36 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2QFR A 1 ? 424 ? O24319 36 ? 459 ? 9 432 2 1 2QFR B 1 ? 424 ? O24319 36 ? 459 ? 9 432 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FE non-polymer . 'FE (III) ION' ? 'Fe 3' 55.845 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NDG D-saccharide . '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.crystals_number 1 _exptl.entry_id 2QFR _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 4.45 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 72.34 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 4.0 _exptl_crystal_grow.temp 291 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details '2M Ammonium sulfate, 0.1 M acetate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 291K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 290 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'RIGAKU RAXIS IV++' _diffrn_detector.pdbx_collection_date 2005-04-10 _diffrn_detector.details Osmic # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator Mirrors _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.541 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'RIGAKU FR-E+ DW' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.541 _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? # _reflns.entry_id 2QFR _reflns.observed_criterion_sigma_F 0.0 _reflns.observed_criterion_sigma_I 0.0 _reflns.d_resolution_high 2.4 _reflns.d_resolution_low 43 _reflns.number_all 67185 _reflns.number_obs 55092 _reflns.percent_possible_obs 82.6 _reflns.pdbx_Rmerge_I_obs 0.115 _reflns.pdbx_Rsym_value 0.115 _reflns.pdbx_netI_over_sigmaI 7.1 _reflns.B_iso_Wilson_estimate 38 _reflns.pdbx_redundancy 2.76 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.40 _reflns_shell.d_res_low 2.55 _reflns_shell.percent_possible_obs ? _reflns_shell.percent_possible_all 52.0 _reflns_shell.Rmerge_I_obs 0.302 _reflns_shell.meanI_over_sigI_obs 2.1 _reflns_shell.pdbx_Rsym_value 0.302 _reflns_shell.pdbx_redundancy 1.6 _reflns_shell.number_unique_all 8320 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2QFR _refine.ls_d_res_high 2.400 _refine.ls_d_res_low 43.0 _refine.pdbx_ls_sigma_F 0.0 _refine.ls_percent_reflns_obs 82.000 _refine.ls_number_reflns_obs 55092 _refine.ls_R_factor_R_work 0.171 _refine.ls_R_factor_R_free 0.211 _refine.ls_percent_reflns_R_free 8.400 _refine.ls_number_reflns_R_free 5612 _refine.B_iso_mean 27.427 _refine.solvent_model_param_bsol 31.514 _refine.aniso_B[1][1] -1.958 _refine.aniso_B[2][2] -1.958 _refine.aniso_B[3][3] 3.916 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.pdbx_ls_sigma_I 0.0 _refine.ls_number_reflns_all 55092 _refine.ls_R_factor_all 0.173 _refine.ls_R_factor_obs 0.173 _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model '4kbp chain b' _refine.pdbx_ls_cross_valid_method throughtout _refine.pdbx_R_Free_selection_details random _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_isotropic_thermal_model ? _refine.details ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_overall_ESU_R ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_phase_error ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6974 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 138 _refine_hist.number_atoms_solvent 401 _refine_hist.number_atoms_total 7513 _refine_hist.d_res_high 2.400 _refine_hist.d_res_low 43.0 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d ? 0.007 ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? 1.285 ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it ? 1.045 1.500 ? 'X-RAY DIFFRACTION' ? c_scbond_it ? 1.907 2.000 ? 'X-RAY DIFFRACTION' ? c_mcangle_it ? 1.733 2.000 ? 'X-RAY DIFFRACTION' ? c_scangle_it ? 2.947 2.500 ? 'X-RAY DIFFRACTION' ? # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 CNS_TOPPAR:protein_rep.param CNS_TOPPAR:protein.top 'X-RAY DIFFRACTION' 2 CNS_TOPPAR:water_rep.param CNS_TOPPAR:water.top 'X-RAY DIFFRACTION' 3 CNS_TOPPAR:ion.param CNS_TOPPAR:ion.top 'X-RAY DIFFRACTION' 4 CNS_TOPPAR:carbohydrate.param CNS_TOPPAR:carbohydrate.top 'X-RAY DIFFRACTION' # _struct.entry_id 2QFR _struct.title 'Crystal structure of red kidney bean purple acid phosphatase with bound sulfate' _struct.pdbx_descriptor 'Purple acid phosphatase (E.C.3.1.3.2)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2QFR _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'binuclear metal centre, substrate analog, Hydrolase' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 4 ? F N N 4 ? G N N 5 ? H N N 6 ? I N N 6 ? J N N 5 ? K N N 2 ? L N N 3 ? M N N 4 ? N N N 4 ? O N N 6 ? P N N 6 ? Q N N 6 ? R N N 6 ? S N N 7 ? T N N 7 ? # _struct_biol.id 1 _struct_biol.details 'The biological assembly is a dimer which corresponds to the contents of the asymmetric unit.' # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 7 ? ARG A 11 ? SER A 15 ARG A 19 5 ? 5 HELX_P HELX_P2 2 SER A 131 ? SER A 144 ? SER A 139 SER A 152 1 ? 14 HELX_P HELX_P3 3 TYR A 159 ? ASP A 167 ? TYR A 167 ASP A 175 5 ? 9 HELX_P HELX_P4 4 ASN A 168 ? ALA A 183 ? ASN A 176 ALA A 191 1 ? 16 HELX_P HELX_P5 5 GLY A 192 ? ILE A 196 ? GLY A 200 ILE A 204 5 ? 5 HELX_P HELX_P6 6 ALA A 199 ? ASN A 203 ? ALA A 207 ASN A 211 5 ? 5 HELX_P HELX_P7 7 PHE A 208 ? TYR A 215 ? PHE A 216 TYR A 223 1 ? 8 HELX_P HELX_P8 8 PRO A 218 ? GLN A 223 ? PRO A 226 GLN A 231 5 ? 6 HELX_P HELX_P9 9 THR A 252 ? LYS A 264 ? THR A 260 LYS A 272 1 ? 13 HELX_P HELX_P10 10 GLY A 292 ? TYR A 306 ? GLY A 300 TYR A 314 1 ? 15 HELX_P HELX_P11 11 SER B 7 ? ARG B 11 ? SER B 15 ARG B 19 5 ? 5 HELX_P HELX_P12 12 SER B 131 ? SER B 144 ? SER B 139 SER B 152 1 ? 14 HELX_P HELX_P13 13 TYR B 159 ? ASP B 167 ? TYR B 167 ASP B 175 5 ? 9 HELX_P HELX_P14 14 ASN B 168 ? ALA B 183 ? ASN B 176 ALA B 191 1 ? 16 HELX_P HELX_P15 15 GLY B 192 ? GLU B 197 ? GLY B 200 GLU B 205 1 ? 6 HELX_P HELX_P16 16 ALA B 199 ? ASN B 203 ? ALA B 207 ASN B 211 5 ? 5 HELX_P HELX_P17 17 PHE B 208 ? TYR B 215 ? PHE B 216 TYR B 223 1 ? 8 HELX_P HELX_P18 18 PRO B 218 ? GLN B 223 ? PRO B 226 GLN B 231 5 ? 6 HELX_P HELX_P19 19 THR B 252 ? LYS B 264 ? THR B 260 LYS B 272 1 ? 13 HELX_P HELX_P20 20 GLY B 292 ? TYR B 306 ? GLY B 300 TYR B 314 1 ? 15 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 337 SG ? ? ? 1_555 B CYS 337 SG ? ? A CYS 345 B CYS 345 1_555 ? ? ? ? ? ? ? 2.025 ? metalc1 metalc ? ? A ASP 127 OD2 ? ? ? 1_555 C FE . FE ? ? A ASP 135 A FE 433 1_555 ? ? ? ? ? ? ? 1.831 ? covale1 covale ? ? A ASN 135 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 143 A NAG 451 1_555 ? ? ? ? ? ? ? 1.453 ? metalc2 metalc ? ? A ASP 156 OD2 ? ? ? 1_555 D ZN . ZN ? ? A ASP 164 A ZN 434 1_555 ? ? ? ? ? ? ? 2.350 ? metalc3 metalc ? ? A ASP 156 OD2 ? ? ? 1_555 C FE . FE ? ? A ASP 164 A FE 433 1_555 ? ? ? ? ? ? ? 2.065 ? metalc4 metalc ? ? A TYR 159 OH ? ? ? 1_555 C FE . FE ? ? A TYR 167 A FE 433 1_555 ? ? ? ? ? ? ? 2.000 ? metalc5 metalc ? ? A ASN 193 OD1 ? ? ? 1_555 D ZN . ZN ? ? A ASN 201 A ZN 434 1_555 ? ? ? ? ? ? ? 2.008 ? metalc6 metalc ? ? A HIS 278 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 286 A ZN 434 1_555 ? ? ? ? ? ? ? 2.043 ? metalc7 metalc ? ? A HIS 315 ND1 ? ? ? 1_555 D ZN . ZN ? ? A HIS 323 A ZN 434 1_555 ? ? ? ? ? ? ? 2.089 ? metalc8 metalc ? ? A HIS 317 NE2 ? ? ? 1_555 C FE . FE ? ? A HIS 325 A FE 433 1_555 ? ? ? ? ? ? ? 2.358 ? covale2 covale ? ? A ASN 388 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 396 A NAG 452 1_555 ? ? ? ? ? ? ? 1.461 ? covale3 covale ? ? B ASN 73 ND2 ? ? ? 1_555 O NAG . C1 ? ? B ASN 81 B NAG 450 1_555 ? ? ? ? ? ? ? 1.454 ? covale4 covale ? ? B ASN 101 ND2 ? ? ? 1_555 R NAG . C1 ? ? B ASN 109 B NAG 453 1_555 ? ? ? ? ? ? ? 1.450 ? metalc9 metalc ? ? B ASP 127 OD2 ? ? ? 1_555 K FE . FE ? ? B ASP 135 B FE 433 1_555 ? ? ? ? ? ? ? 1.846 ? covale5 covale ? ? B ASN 135 ND2 ? ? ? 1_555 P NAG . C1 ? ? B ASN 143 B NAG 451 1_555 ? ? ? ? ? ? ? 1.452 ? metalc10 metalc ? ? B ASP 156 OD2 ? ? ? 1_555 K FE . FE ? ? B ASP 164 B FE 433 1_555 ? ? ? ? ? ? ? 2.164 ? metalc11 metalc ? ? B ASP 156 OD2 ? ? ? 1_555 L ZN . ZN ? ? B ASP 164 B ZN 434 1_555 ? ? ? ? ? ? ? 2.234 ? metalc12 metalc ? ? B TYR 159 OH ? ? ? 1_555 K FE . FE ? ? B TYR 167 B FE 433 1_555 ? ? ? ? ? ? ? 1.905 ? metalc13 metalc ? ? B ASN 193 OD1 ? ? ? 1_555 L ZN . ZN ? ? B ASN 201 B ZN 434 1_555 ? ? ? ? ? ? ? 2.130 ? metalc14 metalc ? ? B HIS 278 NE2 ? ? ? 1_555 L ZN . ZN ? ? B HIS 286 B ZN 434 1_555 ? ? ? ? ? ? ? 2.024 ? metalc15 metalc ? ? B HIS 315 ND1 ? ? ? 1_555 L ZN . ZN ? ? B HIS 323 B ZN 434 1_555 ? ? ? ? ? ? ? 2.068 ? metalc16 metalc ? ? B HIS 317 NE2 ? ? ? 1_555 K FE . FE ? ? B HIS 325 B FE 433 1_555 ? ? ? ? ? ? ? 2.252 ? covale6 covale ? ? B ASN 388 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 396 B NAG 452 1_555 ? ? ? ? ? ? ? 1.458 ? metalc17 metalc ? ? C FE . FE ? ? ? 1_555 S HOH . O ? ? A FE 433 A HOH 454 1_555 ? ? ? ? ? ? ? 2.207 ? metalc18 metalc ? ? D ZN . ZN ? ? ? 1_555 S HOH . O ? ? A ZN 434 A HOH 454 1_555 ? ? ? ? ? ? ? 2.374 ? metalc19 metalc ? ? K FE . FE ? ? ? 1_555 T HOH . O ? ? B FE 433 B HOH 454 1_555 ? ? ? ? ? ? ? 2.048 ? metalc20 metalc ? ? L ZN . ZN ? ? ? 1_555 T HOH . O ? ? B ZN 434 B HOH 454 1_555 ? ? ? ? ? ? ? 2.256 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLN 366 A . ? GLN 374 A PRO 367 A ? PRO 375 A 1 -1.23 2 GLN 366 B . ? GLN 374 B PRO 367 B ? PRO 375 B 1 0.00 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 4 ? C ? 6 ? D ? 7 ? E ? 2 ? F ? 4 ? G ? 4 ? H ? 6 ? I ? 7 ? J ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? anti-parallel C 4 5 ? anti-parallel C 5 6 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? parallel D 3 4 ? parallel D 4 5 ? parallel D 5 6 ? anti-parallel D 6 7 ? anti-parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? parallel H 2 3 ? parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? parallel I 3 4 ? parallel I 4 5 ? parallel I 5 6 ? anti-parallel I 6 7 ? anti-parallel J 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLN A 20 ? GLN A 26 ? GLN A 28 GLN A 34 A 2 MET A 34 ? THR A 40 ? MET A 42 THR A 48 A 3 PHE A 78 ? ILE A 84 ? PHE A 86 ILE A 92 A 4 LYS A 65 ? SER A 67 ? LYS A 73 SER A 75 B 1 ARG A 60 ? LYS A 63 ? ARG A 68 LYS A 71 B 2 ALA A 48 ? SER A 53 ? ALA A 56 SER A 61 B 3 LYS A 92 ? VAL A 97 ? LYS A 100 VAL A 105 B 4 ARG A 104 ? ILE A 109 ? ARG A 112 ILE A 117 C 1 TRP A 187 ? TRP A 189 ? TRP A 195 TRP A 197 C 2 THR A 150 ? PHE A 153 ? THR A 158 PHE A 161 C 3 TYR A 120 ? ILE A 125 ? TYR A 128 ILE A 133 C 4 GLY A 380 ? ILE A 386 ? GLY A 388 ILE A 394 C 5 HIS A 391 ? ARG A 398 ? HIS A 399 ARG A 406 C 6 ASP A 408 ? PHE A 413 ? ASP A 416 PHE A 421 D 1 TYR A 230 ? ARG A 234 ? TYR A 238 ARG A 242 D 2 ALA A 237 ? VAL A 241 ? ALA A 245 VAL A 249 D 3 TRP A 272 ? LEU A 276 ? TRP A 280 LEU A 284 D 4 VAL A 310 ? ALA A 313 ? VAL A 318 ALA A 321 D 5 VAL A 347 ? ILE A 351 ? VAL A 355 ILE A 359 D 6 TYR A 319 ? SER A 322 ? TYR A 327 SER A 330 D 7 SER A 372 ? GLU A 376 ? SER A 380 GLU A 384 E 1 VAL A 325 ? SER A 326 ? VAL A 333 SER A 334 E 2 VAL A 340 ? LYS A 341 ? VAL A 348 LYS A 349 F 1 GLN B 20 ? GLN B 26 ? GLN B 28 GLN B 34 F 2 MET B 34 ? THR B 40 ? MET B 42 THR B 48 F 3 PHE B 78 ? ILE B 84 ? PHE B 86 ILE B 92 F 4 LYS B 65 ? SER B 67 ? LYS B 73 SER B 75 G 1 ARG B 60 ? LYS B 63 ? ARG B 68 LYS B 71 G 2 ALA B 48 ? SER B 53 ? ALA B 56 SER B 61 G 3 LYS B 92 ? VAL B 97 ? LYS B 100 VAL B 105 G 4 ARG B 104 ? ILE B 109 ? ARG B 112 ILE B 117 H 1 TRP B 187 ? ILE B 188 ? TRP B 195 ILE B 196 H 2 THR B 150 ? PHE B 153 ? THR B 158 PHE B 161 H 3 TYR B 120 ? ILE B 125 ? TYR B 128 ILE B 133 H 4 GLY B 380 ? ILE B 386 ? GLY B 388 ILE B 394 H 5 HIS B 391 ? ARG B 398 ? HIS B 399 ARG B 406 H 6 ASP B 408 ? PHE B 413 ? ASP B 416 PHE B 421 I 1 TYR B 230 ? ARG B 234 ? TYR B 238 ARG B 242 I 2 ALA B 237 ? VAL B 241 ? ALA B 245 VAL B 249 I 3 TRP B 272 ? LEU B 276 ? TRP B 280 LEU B 284 I 4 VAL B 310 ? ALA B 313 ? VAL B 318 ALA B 321 I 5 VAL B 347 ? ILE B 351 ? VAL B 355 ILE B 359 I 6 TYR B 319 ? SER B 322 ? TYR B 327 SER B 330 I 7 SER B 372 ? GLU B 376 ? SER B 380 GLU B 384 J 1 VAL B 325 ? SER B 326 ? VAL B 333 SER B 334 J 2 VAL B 340 ? LYS B 341 ? VAL B 348 LYS B 349 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 25 ? N THR A 33 O ILE A 35 ? O ILE A 43 A 2 3 N ILE A 36 ? N ILE A 44 O THR A 82 ? O THR A 90 A 3 4 O ILE A 79 ? O ILE A 87 N SER A 67 ? N SER A 75 B 1 2 O ARG A 60 ? O ARG A 68 N TYR A 51 ? N TYR A 59 B 2 3 N TRP A 52 ? N TRP A 60 O TYR A 94 ? O TYR A 102 B 3 4 N TYR A 93 ? N TYR A 101 O PHE A 108 ? O PHE A 116 C 1 2 O ILE A 188 ? O ILE A 196 N VAL A 151 ? N VAL A 159 C 2 3 O THR A 150 ? O THR A 158 N GLY A 123 ? N GLY A 131 C 3 4 N TYR A 120 ? N TYR A 128 O ILE A 386 ? O ILE A 394 C 4 5 N ASP A 385 ? N ASP A 393 O HIS A 393 ? O HIS A 401 C 5 6 N ALA A 392 ? N ALA A 400 O PHE A 412 ? O PHE A 420 D 1 2 N TYR A 230 ? N TYR A 238 O VAL A 241 ? O VAL A 249 D 2 3 N ILE A 240 ? N ILE A 248 O LEU A 276 ? O LEU A 284 D 3 4 N VAL A 275 ? N VAL A 283 O PHE A 312 ? O PHE A 320 D 4 5 N VAL A 311 ? N VAL A 319 O ILE A 349 ? O ILE A 357 D 5 6 O TYR A 348 ? O TYR A 356 N SER A 322 ? N SER A 330 D 6 7 N ARG A 321 ? N ARG A 329 O PHE A 374 ? O PHE A 382 E 1 2 N SER A 326 ? N SER A 334 O VAL A 340 ? O VAL A 348 F 1 2 N THR B 25 ? N THR B 33 O ILE B 35 ? O ILE B 43 F 2 3 N ILE B 36 ? N ILE B 44 O THR B 82 ? O THR B 90 F 3 4 O ILE B 79 ? O ILE B 87 N SER B 67 ? N SER B 75 G 1 2 O ARG B 60 ? O ARG B 68 N TYR B 51 ? N TYR B 59 G 2 3 N ARG B 50 ? N ARG B 58 O GLU B 96 ? O GLU B 104 G 3 4 N TYR B 93 ? N TYR B 101 O PHE B 108 ? O PHE B 116 H 1 2 O ILE B 188 ? O ILE B 196 N VAL B 151 ? N VAL B 159 H 2 3 O THR B 150 ? O THR B 158 N GLY B 123 ? N GLY B 131 H 3 4 N PHE B 122 ? N PHE B 130 O PHE B 384 ? O PHE B 392 H 4 5 N ASP B 385 ? N ASP B 393 O HIS B 393 ? O HIS B 401 H 5 6 N ALA B 392 ? N ALA B 400 O PHE B 412 ? O PHE B 420 I 1 2 N TYR B 230 ? N TYR B 238 O VAL B 241 ? O VAL B 249 I 2 3 N ILE B 240 ? N ILE B 248 O LEU B 276 ? O LEU B 284 I 3 4 N VAL B 275 ? N VAL B 283 O PHE B 312 ? O PHE B 320 I 4 5 N ALA B 313 ? N ALA B 321 O ILE B 351 ? O ILE B 359 I 5 6 O TYR B 348 ? O TYR B 356 N SER B 322 ? N SER B 330 I 6 7 N ARG B 321 ? N ARG B 329 O PHE B 374 ? O PHE B 382 J 1 2 N SER B 326 ? N SER B 334 O VAL B 340 ? O VAL B 348 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NDG A 450' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 451' AC3 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG A 452' AC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NDG A 453' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 450' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 451' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 452' AC8 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 453' AC9 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE FE A 433' BC1 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE ZN A 434' BC2 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE SO4 A 435' BC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE SO4 A 437' BC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE FE B 433' BC5 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE ZN B 434' BC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 B 435' BC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 B 437' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 ASN A 73 ? ASN A 81 . ? 1_555 ? 2 AC1 6 ASN A 165 ? ASN A 173 . ? 1_555 ? 3 AC1 6 HOH S . ? HOH A 548 . ? 1_555 ? 4 AC1 6 HOH S . ? HOH A 557 . ? 1_555 ? 5 AC1 6 TYR B 16 ? TYR B 24 . ? 6_765 ? 6 AC1 6 ASP B 42 ? ASP B 50 . ? 6_765 ? 7 AC2 5 ASP A 8 ? ASP A 16 . ? 1_555 ? 8 AC2 5 ASN A 135 ? ASN A 143 . ? 1_555 ? 9 AC2 5 SER A 139 ? SER A 147 . ? 1_555 ? 10 AC2 5 ARG A 180 ? ARG A 188 . ? 1_555 ? 11 AC2 5 HOH S . ? HOH A 566 . ? 1_555 ? 12 AC3 7 LYS A 387 ? LYS A 395 . ? 1_555 ? 13 AC3 7 ASN A 388 ? ASN A 396 . ? 1_555 ? 14 AC3 7 THR A 390 ? THR A 398 . ? 1_555 ? 15 AC3 7 HIS A 391 ? HIS A 399 . ? 1_555 ? 16 AC3 7 HOH S . ? HOH A 461 . ? 1_555 ? 17 AC3 7 HOH S . ? HOH A 550 . ? 1_555 ? 18 AC3 7 HOH S . ? HOH A 568 . ? 1_555 ? 19 AC4 5 GLU A 43 ? GLU A 51 . ? 1_555 ? 20 AC4 5 ARG A 100 ? ARG A 108 . ? 1_555 ? 21 AC4 5 ASN A 101 ? ASN A 109 . ? 1_555 ? 22 AC4 5 HOH S . ? HOH A 530 . ? 1_555 ? 23 AC4 5 HOH S . ? HOH A 635 . ? 1_555 ? 24 AC5 6 TYR A 16 ? TYR A 24 . ? 6_765 ? 25 AC5 6 GLU A 43 ? GLU A 51 . ? 6_765 ? 26 AC5 6 ASN B 73 ? ASN B 81 . ? 1_555 ? 27 AC5 6 ASN B 165 ? ASN B 173 . ? 1_555 ? 28 AC5 6 HOH T . ? HOH B 464 . ? 1_555 ? 29 AC5 6 HOH T . ? HOH B 550 . ? 1_555 ? 30 AC6 5 ASP B 8 ? ASP B 16 . ? 1_555 ? 31 AC6 5 ASN B 135 ? ASN B 143 . ? 1_555 ? 32 AC6 5 SER B 139 ? SER B 147 . ? 1_555 ? 33 AC6 5 HOH T . ? HOH B 539 . ? 1_555 ? 34 AC6 5 HOH T . ? HOH B 642 . ? 1_555 ? 35 AC7 4 ASN B 388 ? ASN B 396 . ? 1_555 ? 36 AC7 4 HIS B 391 ? HIS B 399 . ? 1_555 ? 37 AC7 4 HOH T . ? HOH B 462 . ? 1_555 ? 38 AC7 4 HOH T . ? HOH B 475 . ? 1_555 ? 39 AC8 4 GLU B 43 ? GLU B 51 . ? 1_555 ? 40 AC8 4 ARG B 100 ? ARG B 108 . ? 1_555 ? 41 AC8 4 ASN B 101 ? ASN B 109 . ? 1_555 ? 42 AC8 4 HOH T . ? HOH B 482 . ? 1_555 ? 43 AC9 6 ASP A 127 ? ASP A 135 . ? 1_555 ? 44 AC9 6 ASP A 156 ? ASP A 164 . ? 1_555 ? 45 AC9 6 TYR A 159 ? TYR A 167 . ? 1_555 ? 46 AC9 6 HIS A 317 ? HIS A 325 . ? 1_555 ? 47 AC9 6 ZN D . ? ZN A 434 . ? 1_555 ? 48 AC9 6 HOH S . ? HOH A 454 . ? 1_555 ? 49 BC1 7 ASP A 127 ? ASP A 135 . ? 1_555 ? 50 BC1 7 ASP A 156 ? ASP A 164 . ? 1_555 ? 51 BC1 7 ASN A 193 ? ASN A 201 . ? 1_555 ? 52 BC1 7 HIS A 278 ? HIS A 286 . ? 1_555 ? 53 BC1 7 HIS A 315 ? HIS A 323 . ? 1_555 ? 54 BC1 7 FE C . ? FE A 433 . ? 1_555 ? 55 BC1 7 HOH S . ? HOH A 454 . ? 1_555 ? 56 BC2 7 ASN A 193 ? ASN A 201 . ? 1_555 ? 57 BC2 7 HIS A 194 ? HIS A 202 . ? 1_555 ? 58 BC2 7 HIS A 287 ? HIS A 295 . ? 1_555 ? 59 BC2 7 HIS A 288 ? HIS A 296 . ? 1_555 ? 60 BC2 7 HIS A 315 ? HIS A 323 . ? 1_555 ? 61 BC2 7 HIS A 317 ? HIS A 325 . ? 1_555 ? 62 BC2 7 HOH S . ? HOH A 454 . ? 1_555 ? 63 BC3 5 ARG A 250 ? ARG A 258 . ? 1_555 ? 64 BC3 5 TYR A 255 ? TYR A 263 . ? 1_555 ? 65 BC3 5 LYS A 259 ? LYS A 267 . ? 1_555 ? 66 BC3 5 HOH S . ? HOH A 499 . ? 1_555 ? 67 BC3 5 HOH S . ? HOH A 608 . ? 1_555 ? 68 BC4 6 ASP B 127 ? ASP B 135 . ? 1_555 ? 69 BC4 6 ASP B 156 ? ASP B 164 . ? 1_555 ? 70 BC4 6 TYR B 159 ? TYR B 167 . ? 1_555 ? 71 BC4 6 HIS B 317 ? HIS B 325 . ? 1_555 ? 72 BC4 6 ZN L . ? ZN B 434 . ? 1_555 ? 73 BC4 6 HOH T . ? HOH B 454 . ? 1_555 ? 74 BC5 8 ASP B 127 ? ASP B 135 . ? 1_555 ? 75 BC5 8 ASP B 156 ? ASP B 164 . ? 1_555 ? 76 BC5 8 ASN B 193 ? ASN B 201 . ? 1_555 ? 77 BC5 8 HIS B 278 ? HIS B 286 . ? 1_555 ? 78 BC5 8 HIS B 315 ? HIS B 323 . ? 1_555 ? 79 BC5 8 FE K . ? FE B 433 . ? 1_555 ? 80 BC5 8 SO4 M . ? SO4 B 435 . ? 1_555 ? 81 BC5 8 HOH T . ? HOH B 454 . ? 1_555 ? 82 BC6 6 ASN B 193 ? ASN B 201 . ? 1_555 ? 83 BC6 6 HIS B 194 ? HIS B 202 . ? 1_555 ? 84 BC6 6 HIS B 287 ? HIS B 295 . ? 1_555 ? 85 BC6 6 HIS B 288 ? HIS B 296 . ? 1_555 ? 86 BC6 6 ZN L . ? ZN B 434 . ? 1_555 ? 87 BC6 6 HOH T . ? HOH B 454 . ? 1_555 ? 88 BC7 3 ARG B 250 ? ARG B 258 . ? 1_555 ? 89 BC7 3 TYR B 255 ? TYR B 263 . ? 1_555 ? 90 BC7 3 LYS B 259 ? LYS B 267 . ? 1_555 ? # _atom_sites.entry_id 2QFR _atom_sites.fract_transf_matrix[1][1] 0.006755 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006755 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.006246 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C FE N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ARG A 1 1 ? 143.189 32.900 -62.686 1.00 37.17 ? 9 ARG A N 1 ATOM 2 C CA . ARG A 1 1 ? 142.928 32.470 -61.277 1.00 37.25 ? 9 ARG A CA 1 ATOM 3 C C . ARG A 1 1 ? 142.577 33.623 -60.343 1.00 35.55 ? 9 ARG A C 1 ATOM 4 O O . ARG A 1 1 ? 142.564 33.455 -59.119 1.00 34.51 ? 9 ARG A O 1 ATOM 5 C CB . ARG A 1 1 ? 144.141 31.736 -60.700 1.00 40.20 ? 9 ARG A CB 1 ATOM 6 C CG . ARG A 1 1 ? 144.321 30.314 -61.199 1.00 45.45 ? 9 ARG A CG 1 ATOM 7 C CD . ARG A 1 1 ? 145.256 29.527 -60.281 1.00 50.07 ? 9 ARG A CD 1 ATOM 8 N NE . ARG A 1 1 ? 144.925 29.683 -58.858 1.00 55.19 ? 9 ARG A NE 1 ATOM 9 C CZ . ARG A 1 1 ? 143.769 29.328 -58.291 1.00 56.53 ? 9 ARG A CZ 1 ATOM 10 N NH1 . ARG A 1 1 ? 142.796 28.783 -59.014 1.00 57.61 ? 9 ARG A NH1 1 ATOM 11 N NH2 . ARG A 1 1 ? 143.587 29.514 -56.989 1.00 56.43 ? 9 ARG A NH2 1 ATOM 12 N N . ASP A 1 2 ? 142.305 34.796 -60.908 1.00 33.97 ? 10 ASP A N 1 ATOM 13 C CA . ASP A 1 2 ? 141.950 35.943 -60.082 1.00 33.61 ? 10 ASP A CA 1 ATOM 14 C C . ASP A 1 2 ? 140.555 35.758 -59.509 1.00 32.66 ? 10 ASP A C 1 ATOM 15 O O . ASP A 1 2 ? 139.689 35.153 -60.139 1.00 33.20 ? 10 ASP A O 1 ATOM 16 C CB . ASP A 1 2 ? 142.006 37.244 -60.895 1.00 34.10 ? 10 ASP A CB 1 ATOM 17 C CG . ASP A 1 2 ? 143.396 37.875 -60.902 1.00 35.62 ? 10 ASP A CG 1 ATOM 18 O OD1 . ASP A 1 2 ? 144.324 37.301 -60.290 1.00 36.58 ? 10 ASP A OD1 1 ATOM 19 O OD2 . ASP A 1 2 ? 143.561 38.949 -61.520 1.00 35.85 ? 10 ASP A OD2 1 ATOM 20 N N . MET A 1 3 ? 140.342 36.263 -58.301 1.00 31.57 ? 11 MET A N 1 ATOM 21 C CA . MET A 1 3 ? 139.036 36.154 -57.675 1.00 31.76 ? 11 MET A CA 1 ATOM 22 C C . MET A 1 3 ? 138.033 36.998 -58.465 1.00 32.48 ? 11 MET A C 1 ATOM 23 O O . MET A 1 3 ? 138.306 38.150 -58.806 1.00 33.31 ? 11 MET A O 1 ATOM 24 C CB . MET A 1 3 ? 139.104 36.627 -56.220 1.00 30.25 ? 11 MET A CB 1 ATOM 25 C CG . MET A 1 3 ? 140.119 35.864 -55.385 1.00 29.68 ? 11 MET A CG 1 ATOM 26 S SD . MET A 1 3 ? 140.112 36.339 -53.655 1.00 29.45 ? 11 MET A SD 1 ATOM 27 C CE . MET A 1 3 ? 141.120 37.810 -53.710 1.00 31.10 ? 11 MET A CE 1 ATOM 28 N N . PRO A 1 4 ? 136.868 36.421 -58.795 1.00 33.41 ? 12 PRO A N 1 ATOM 29 C CA . PRO A 1 4 ? 135.847 37.155 -59.551 1.00 32.81 ? 12 PRO A CA 1 ATOM 30 C C . PRO A 1 4 ? 135.280 38.356 -58.785 1.00 32.51 ? 12 PRO A C 1 ATOM 31 O O . PRO A 1 4 ? 135.309 38.391 -57.551 1.00 32.05 ? 12 PRO A O 1 ATOM 32 C CB . PRO A 1 4 ? 134.802 36.081 -59.848 1.00 32.65 ? 12 PRO A CB 1 ATOM 33 C CG . PRO A 1 4 ? 134.973 35.107 -58.723 1.00 32.64 ? 12 PRO A CG 1 ATOM 34 C CD . PRO A 1 4 ? 136.463 35.020 -58.586 1.00 32.74 ? 12 PRO A CD 1 ATOM 35 N N . LEU A 1 5 ? 134.770 39.335 -59.527 1.00 32.22 ? 13 LEU A N 1 ATOM 36 C CA . LEU A 1 5 ? 134.221 40.551 -58.939 1.00 33.07 ? 13 LEU A CA 1 ATOM 37 C C . LEU A 1 5 ? 133.162 40.329 -57.864 1.00 34.36 ? 13 LEU A C 1 ATOM 38 O O . LEU A 1 5 ? 132.974 41.184 -56.998 1.00 34.44 ? 13 LEU A O 1 ATOM 39 C CB . LEU A 1 5 ? 133.656 41.441 -60.042 1.00 32.37 ? 13 LEU A CB 1 ATOM 40 C CG . LEU A 1 5 ? 134.672 41.926 -61.080 1.00 32.41 ? 13 LEU A CG 1 ATOM 41 C CD1 . LEU A 1 5 ? 133.955 42.466 -62.304 1.00 33.01 ? 13 LEU A CD1 1 ATOM 42 C CD2 . LEU A 1 5 ? 135.561 42.987 -60.462 1.00 32.36 ? 13 LEU A CD2 1 ATOM 43 N N . ASP A 1 6 ? 132.476 39.191 -57.905 1.00 36.29 ? 14 ASP A N 1 ATOM 44 C CA . ASP A 1 6 ? 131.437 38.908 -56.915 1.00 38.07 ? 14 ASP A CA 1 ATOM 45 C C . ASP A 1 6 ? 131.957 38.290 -55.621 1.00 37.37 ? 14 ASP A C 1 ATOM 46 O O . ASP A 1 6 ? 131.184 38.050 -54.691 1.00 38.01 ? 14 ASP A O 1 ATOM 47 C CB . ASP A 1 6 ? 130.358 37.995 -57.514 1.00 41.70 ? 14 ASP A CB 1 ATOM 48 C CG . ASP A 1 6 ? 130.938 36.747 -58.180 1.00 46.94 ? 14 ASP A CG 1 ATOM 49 O OD1 . ASP A 1 6 ? 131.672 35.984 -57.508 1.00 48.79 ? 14 ASP A OD1 1 ATOM 50 O OD2 . ASP A 1 6 ? 130.651 36.531 -59.381 1.00 49.14 ? 14 ASP A OD2 1 ATOM 51 N N . SER A 1 7 ? 133.259 38.035 -55.554 1.00 36.22 ? 15 SER A N 1 ATOM 52 C CA . SER A 1 7 ? 133.843 37.436 -54.363 1.00 35.19 ? 15 SER A CA 1 ATOM 53 C C . SER A 1 7 ? 133.570 38.271 -53.119 1.00 35.09 ? 15 SER A C 1 ATOM 54 O O . SER A 1 7 ? 133.540 39.499 -53.165 1.00 34.62 ? 15 SER A O 1 ATOM 55 C CB . SER A 1 7 ? 135.346 37.249 -54.553 1.00 34.95 ? 15 SER A CB 1 ATOM 56 O OG . SER A 1 7 ? 135.606 36.417 -55.667 1.00 36.26 ? 15 SER A OG 1 ATOM 57 N N . ASP A 1 8 ? 133.367 37.586 -52.002 1.00 35.83 ? 16 ASP A N 1 ATOM 58 C CA . ASP A 1 8 ? 133.073 38.245 -50.738 1.00 35.94 ? 16 ASP A CA 1 ATOM 59 C C . ASP A 1 8 ? 134.082 39.313 -50.322 1.00 35.01 ? 16 ASP A C 1 ATOM 60 O O . ASP A 1 8 ? 133.696 40.342 -49.766 1.00 34.66 ? 16 ASP A O 1 ATOM 61 C CB . ASP A 1 8 ? 132.933 37.202 -49.617 1.00 38.15 ? 16 ASP A CB 1 ATOM 62 C CG . ASP A 1 8 ? 134.154 36.293 -49.489 1.00 39.95 ? 16 ASP A CG 1 ATOM 63 O OD1 . ASP A 1 8 ? 134.147 35.430 -48.583 1.00 40.56 ? 16 ASP A OD1 1 ATOM 64 O OD2 . ASP A 1 8 ? 135.111 36.431 -50.284 1.00 41.00 ? 16 ASP A OD2 1 ATOM 65 N N . VAL A 1 9 ? 135.365 39.079 -50.585 1.00 33.51 ? 17 VAL A N 1 ATOM 66 C CA . VAL A 1 9 ? 136.393 40.042 -50.204 1.00 31.78 ? 17 VAL A CA 1 ATOM 67 C C . VAL A 1 9 ? 136.236 41.386 -50.898 1.00 31.16 ? 17 VAL A C 1 ATOM 68 O O . VAL A 1 9 ? 136.648 42.414 -50.362 1.00 31.30 ? 17 VAL A O 1 ATOM 69 C CB . VAL A 1 9 ? 137.807 39.507 -50.491 1.00 31.29 ? 17 VAL A CB 1 ATOM 70 C CG1 . VAL A 1 9 ? 138.131 38.377 -49.539 1.00 31.64 ? 17 VAL A CG1 1 ATOM 71 C CG2 . VAL A 1 9 ? 137.902 39.030 -51.932 1.00 31.98 ? 17 VAL A CG2 1 ATOM 72 N N . PHE A 1 10 ? 135.637 41.381 -52.084 1.00 30.45 ? 18 PHE A N 1 ATOM 73 C CA . PHE A 1 10 ? 135.443 42.619 -52.831 1.00 30.44 ? 18 PHE A CA 1 ATOM 74 C C . PHE A 1 10 ? 134.128 43.322 -52.483 1.00 31.67 ? 18 PHE A C 1 ATOM 75 O O . PHE A 1 10 ? 133.798 44.370 -53.048 1.00 31.55 ? 18 PHE A O 1 ATOM 76 C CB . PHE A 1 10 ? 135.512 42.339 -54.334 1.00 28.23 ? 18 PHE A CB 1 ATOM 77 C CG . PHE A 1 10 ? 136.817 41.728 -54.783 1.00 26.33 ? 18 PHE A CG 1 ATOM 78 C CD1 . PHE A 1 10 ? 138.019 42.081 -54.168 1.00 23.97 ? 18 PHE A CD1 1 ATOM 79 C CD2 . PHE A 1 10 ? 136.849 40.835 -55.856 1.00 26.08 ? 18 PHE A CD2 1 ATOM 80 C CE1 . PHE A 1 10 ? 139.238 41.556 -54.619 1.00 23.82 ? 18 PHE A CE1 1 ATOM 81 C CE2 . PHE A 1 10 ? 138.065 40.304 -56.318 1.00 25.82 ? 18 PHE A CE2 1 ATOM 82 C CZ . PHE A 1 10 ? 139.259 40.666 -55.698 1.00 24.25 ? 18 PHE A CZ 1 ATOM 83 N N . ARG A 1 11 ? 133.387 42.740 -51.545 1.00 34.18 ? 19 ARG A N 1 ATOM 84 C CA . ARG A 1 11 ? 132.117 43.305 -51.097 1.00 36.96 ? 19 ARG A CA 1 ATOM 85 C C . ARG A 1 11 ? 132.302 44.782 -50.789 1.00 35.56 ? 19 ARG A C 1 ATOM 86 O O . ARG A 1 11 ? 133.286 45.178 -50.165 1.00 36.29 ? 19 ARG A O 1 ATOM 87 C CB . ARG A 1 11 ? 131.633 42.609 -49.819 1.00 41.64 ? 19 ARG A CB 1 ATOM 88 C CG . ARG A 1 11 ? 130.272 41.909 -49.913 1.00 49.75 ? 19 ARG A CG 1 ATOM 89 C CD . ARG A 1 11 ? 130.389 40.546 -50.596 1.00 56.34 ? 19 ARG A CD 1 ATOM 90 N NE . ARG A 1 11 ? 129.525 39.522 -49.995 1.00 61.36 ? 19 ARG A NE 1 ATOM 91 C CZ . ARG A 1 11 ? 129.555 39.159 -48.710 1.00 63.05 ? 19 ARG A CZ 1 ATOM 92 N NH1 . ARG A 1 11 ? 130.402 39.737 -47.861 1.00 62.65 ? 19 ARG A NH1 1 ATOM 93 N NH2 . ARG A 1 11 ? 128.749 38.196 -48.273 1.00 63.25 ? 19 ARG A NH2 1 ATOM 94 N N . VAL A 1 12 ? 131.351 45.599 -51.215 1.00 33.57 ? 20 VAL A N 1 ATOM 95 C CA . VAL A 1 12 ? 131.432 47.022 -50.946 1.00 33.54 ? 20 VAL A CA 1 ATOM 96 C C . VAL A 1 12 ? 130.647 47.296 -49.669 1.00 33.17 ? 20 VAL A C 1 ATOM 97 O O . VAL A 1 12 ? 129.487 46.904 -49.554 1.00 34.33 ? 20 VAL A O 1 ATOM 98 C CB . VAL A 1 12 ? 130.847 47.843 -52.125 1.00 33.00 ? 20 VAL A CB 1 ATOM 99 C CG1 . VAL A 1 12 ? 129.506 47.270 -52.546 1.00 34.28 ? 20 VAL A CG1 1 ATOM 100 C CG2 . VAL A 1 12 ? 130.701 49.307 -51.731 1.00 32.63 ? 20 VAL A CG2 1 ATOM 101 N N . PRO A 1 13 ? 131.279 47.940 -48.673 1.00 32.59 ? 21 PRO A N 1 ATOM 102 C CA . PRO A 1 13 ? 130.569 48.232 -47.423 1.00 32.91 ? 21 PRO A CA 1 ATOM 103 C C . PRO A 1 13 ? 129.275 49.008 -47.679 1.00 33.63 ? 21 PRO A C 1 ATOM 104 O O . PRO A 1 13 ? 129.252 49.951 -48.471 1.00 34.38 ? 21 PRO A O 1 ATOM 105 C CB . PRO A 1 13 ? 131.599 49.019 -46.607 1.00 32.09 ? 21 PRO A CB 1 ATOM 106 C CG . PRO A 1 13 ? 132.521 49.581 -47.644 1.00 33.27 ? 21 PRO A CG 1 ATOM 107 C CD . PRO A 1 13 ? 132.656 48.452 -48.626 1.00 31.89 ? 21 PRO A CD 1 ATOM 108 N N . PRO A 1 14 ? 128.179 48.611 -47.007 1.00 34.35 ? 22 PRO A N 1 ATOM 109 C CA . PRO A 1 14 ? 126.843 49.210 -47.116 1.00 33.47 ? 22 PRO A CA 1 ATOM 110 C C . PRO A 1 14 ? 126.757 50.598 -46.514 1.00 32.83 ? 22 PRO A C 1 ATOM 111 O O . PRO A 1 14 ? 127.565 50.969 -45.662 1.00 32.57 ? 22 PRO A O 1 ATOM 112 C CB . PRO A 1 14 ? 125.977 48.222 -46.360 1.00 33.53 ? 22 PRO A CB 1 ATOM 113 C CG . PRO A 1 14 ? 126.879 47.886 -45.200 1.00 34.11 ? 22 PRO A CG 1 ATOM 114 C CD . PRO A 1 14 ? 128.208 47.633 -45.901 1.00 34.03 ? 22 PRO A CD 1 ATOM 115 N N . GLY A 1 15 ? 125.751 51.350 -46.943 1.00 32.82 ? 23 GLY A N 1 ATOM 116 C CA . GLY A 1 15 ? 125.571 52.699 -46.442 1.00 33.15 ? 23 GLY A CA 1 ATOM 117 C C . GLY A 1 15 ? 125.868 53.705 -47.534 1.00 33.66 ? 23 GLY A C 1 ATOM 118 O O . GLY A 1 15 ? 126.717 53.462 -48.395 1.00 34.16 ? 23 GLY A O 1 ATOM 119 N N . TYR A 1 16 ? 125.171 54.837 -47.512 1.00 33.28 ? 24 TYR A N 1 ATOM 120 C CA . TYR A 1 16 ? 125.387 55.855 -48.528 1.00 31.96 ? 24 TYR A CA 1 ATOM 121 C C . TYR A 1 16 ? 126.787 56.445 -48.409 1.00 31.50 ? 24 TYR A C 1 ATOM 122 O O . TYR A 1 16 ? 127.217 56.814 -47.313 1.00 31.94 ? 24 TYR A O 1 ATOM 123 C CB . TYR A 1 16 ? 124.365 56.987 -48.399 1.00 30.27 ? 24 TYR A CB 1 ATOM 124 C CG . TYR A 1 16 ? 124.585 58.072 -49.431 1.00 27.78 ? 24 TYR A CG 1 ATOM 125 C CD1 . TYR A 1 16 ? 124.352 57.823 -50.781 1.00 27.04 ? 24 TYR A CD1 1 ATOM 126 C CD2 . TYR A 1 16 ? 125.073 59.327 -49.067 1.00 26.70 ? 24 TYR A CD2 1 ATOM 127 C CE1 . TYR A 1 16 ? 124.598 58.791 -51.747 1.00 27.73 ? 24 TYR A CE1 1 ATOM 128 C CE2 . TYR A 1 16 ? 125.324 60.305 -50.026 1.00 27.39 ? 24 TYR A CE2 1 ATOM 129 C CZ . TYR A 1 16 ? 125.084 60.028 -51.367 1.00 28.41 ? 24 TYR A CZ 1 ATOM 130 O OH . TYR A 1 16 ? 125.323 60.979 -52.343 1.00 28.13 ? 24 TYR A OH 1 ATOM 131 N N . ASN A 1 17 ? 127.479 56.534 -49.543 1.00 29.77 ? 25 ASN A N 1 ATOM 132 C CA . ASN A 1 17 ? 128.828 57.084 -49.604 1.00 27.82 ? 25 ASN A CA 1 ATOM 133 C C . ASN A 1 17 ? 129.702 56.548 -48.474 1.00 27.60 ? 25 ASN A C 1 ATOM 134 O O . ASN A 1 17 ? 130.424 57.302 -47.815 1.00 27.12 ? 25 ASN A O 1 ATOM 135 C CB . ASN A 1 17 ? 128.773 58.605 -49.525 1.00 25.44 ? 25 ASN A CB 1 ATOM 136 C CG . ASN A 1 17 ? 129.892 59.262 -50.293 1.00 24.10 ? 25 ASN A CG 1 ATOM 137 O OD1 . ASN A 1 17 ? 130.493 60.231 -49.829 1.00 21.12 ? 25 ASN A OD1 1 ATOM 138 N ND2 . ASN A 1 17 ? 130.175 58.744 -51.485 1.00 22.53 ? 25 ASN A ND2 1 ATOM 139 N N . ALA A 1 18 ? 129.623 55.240 -48.247 1.00 26.92 ? 26 ALA A N 1 ATOM 140 C CA . ALA A 1 18 ? 130.415 54.599 -47.202 1.00 25.75 ? 26 ALA A CA 1 ATOM 141 C C . ALA A 1 18 ? 131.884 54.600 -47.602 1.00 24.57 ? 26 ALA A C 1 ATOM 142 O O . ALA A 1 18 ? 132.228 54.318 -48.747 1.00 24.05 ? 26 ALA A O 1 ATOM 143 C CB . ALA A 1 18 ? 129.941 53.168 -46.986 1.00 24.84 ? 26 ALA A CB 1 ATOM 144 N N . PRO A 1 19 ? 132.773 54.932 -46.660 1.00 24.35 ? 27 PRO A N 1 ATOM 145 C CA . PRO A 1 19 ? 134.206 54.951 -46.960 1.00 23.15 ? 27 PRO A CA 1 ATOM 146 C C . PRO A 1 19 ? 134.641 53.536 -47.310 1.00 22.74 ? 27 PRO A C 1 ATOM 147 O O . PRO A 1 19 ? 134.272 52.583 -46.620 1.00 23.32 ? 27 PRO A O 1 ATOM 148 C CB . PRO A 1 19 ? 134.823 55.432 -45.654 1.00 23.67 ? 27 PRO A CB 1 ATOM 149 C CG . PRO A 1 19 ? 133.747 56.293 -45.068 1.00 24.19 ? 27 PRO A CG 1 ATOM 150 C CD . PRO A 1 19 ? 132.507 55.476 -45.318 1.00 24.41 ? 27 PRO A CD 1 ATOM 151 N N . GLN A 1 20 ? 135.402 53.389 -48.386 1.00 21.82 ? 28 GLN A N 1 ATOM 152 C CA . GLN A 1 20 ? 135.865 52.070 -48.789 1.00 21.82 ? 28 GLN A CA 1 ATOM 153 C C . GLN A 1 20 ? 137.342 52.133 -49.156 1.00 22.34 ? 28 GLN A C 1 ATOM 154 O O . GLN A 1 20 ? 137.907 53.228 -49.294 1.00 21.99 ? 28 GLN A O 1 ATOM 155 C CB . GLN A 1 20 ? 135.037 51.549 -49.972 1.00 22.00 ? 28 GLN A CB 1 ATOM 156 C CG . GLN A 1 20 ? 135.320 52.228 -51.303 1.00 23.58 ? 28 GLN A CG 1 ATOM 157 C CD . GLN A 1 20 ? 134.446 51.701 -52.424 1.00 25.46 ? 28 GLN A CD 1 ATOM 158 O OE1 . GLN A 1 20 ? 133.229 51.891 -52.415 1.00 29.95 ? 28 GLN A OE1 1 ATOM 159 N NE2 . GLN A 1 20 ? 135.058 51.034 -53.395 1.00 27.21 ? 28 GLN A NE2 1 ATOM 160 N N . GLN A 1 21 ? 137.965 50.962 -49.302 1.00 21.90 ? 29 GLN A N 1 ATOM 161 C CA . GLN A 1 21 ? 139.380 50.883 -49.651 1.00 21.48 ? 29 GLN A CA 1 ATOM 162 C C . GLN A 1 21 ? 140.223 51.677 -48.660 1.00 21.10 ? 29 GLN A C 1 ATOM 163 O O . GLN A 1 21 ? 141.182 52.338 -49.043 1.00 19.76 ? 29 GLN A O 1 ATOM 164 C CB . GLN A 1 21 ? 139.610 51.446 -51.052 1.00 21.99 ? 29 GLN A CB 1 ATOM 165 C CG . GLN A 1 21 ? 138.903 50.706 -52.163 1.00 21.95 ? 29 GLN A CG 1 ATOM 166 C CD . GLN A 1 21 ? 139.133 51.368 -53.503 1.00 22.43 ? 29 GLN A CD 1 ATOM 167 O OE1 . GLN A 1 21 ? 140.266 51.708 -53.843 1.00 23.29 ? 29 GLN A OE1 1 ATOM 168 N NE2 . GLN A 1 21 ? 138.063 51.559 -54.272 1.00 21.87 ? 29 GLN A NE2 1 ATOM 169 N N . VAL A 1 22 ? 139.854 51.612 -47.389 1.00 20.55 ? 30 VAL A N 1 ATOM 170 C CA . VAL A 1 22 ? 140.564 52.330 -46.346 1.00 21.01 ? 30 VAL A CA 1 ATOM 171 C C . VAL A 1 22 ? 141.913 51.656 -46.095 1.00 22.83 ? 30 VAL A C 1 ATOM 172 O O . VAL A 1 22 ? 141.990 50.434 -45.983 1.00 24.31 ? 30 VAL A O 1 ATOM 173 C CB . VAL A 1 22 ? 139.722 52.342 -45.042 1.00 21.08 ? 30 VAL A CB 1 ATOM 174 C CG1 . VAL A 1 22 ? 140.416 53.164 -43.963 1.00 19.14 ? 30 VAL A CG1 1 ATOM 175 C CG2 . VAL A 1 22 ? 138.334 52.903 -45.331 1.00 18.99 ? 30 VAL A CG2 1 ATOM 176 N N . HIS A 1 23 ? 142.976 52.454 -46.016 1.00 22.53 ? 31 HIS A N 1 ATOM 177 C CA . HIS A 1 23 ? 144.320 51.931 -45.772 1.00 21.05 ? 31 HIS A CA 1 ATOM 178 C C . HIS A 1 23 ? 145.178 53.019 -45.124 1.00 20.69 ? 31 HIS A C 1 ATOM 179 O O . HIS A 1 23 ? 144.974 54.215 -45.383 1.00 20.49 ? 31 HIS A O 1 ATOM 180 C CB . HIS A 1 23 ? 144.949 51.424 -47.084 1.00 18.73 ? 31 HIS A CB 1 ATOM 181 C CG . HIS A 1 23 ? 144.866 52.393 -48.226 1.00 19.27 ? 31 HIS A CG 1 ATOM 182 N ND1 . HIS A 1 23 ? 145.934 53.164 -48.632 1.00 21.28 ? 31 HIS A ND1 1 ATOM 183 C CD2 . HIS A 1 23 ? 143.845 52.702 -49.062 1.00 18.03 ? 31 HIS A CD2 1 ATOM 184 C CE1 . HIS A 1 23 ? 145.578 53.904 -49.668 1.00 17.86 ? 31 HIS A CE1 1 ATOM 185 N NE2 . HIS A 1 23 ? 144.314 53.642 -49.949 1.00 16.45 ? 31 HIS A NE2 1 ATOM 186 N N . ILE A 1 24 ? 146.119 52.609 -44.272 1.00 19.42 ? 32 ILE A N 1 ATOM 187 C CA . ILE A 1 24 ? 146.986 53.553 -43.569 1.00 18.59 ? 32 ILE A CA 1 ATOM 188 C C . ILE A 1 24 ? 148.474 53.243 -43.732 1.00 17.39 ? 32 ILE A C 1 ATOM 189 O O . ILE A 1 24 ? 148.848 52.148 -44.130 1.00 17.24 ? 32 ILE A O 1 ATOM 190 C CB . ILE A 1 24 ? 146.670 53.562 -42.040 1.00 18.94 ? 32 ILE A CB 1 ATOM 191 C CG1 . ILE A 1 24 ? 147.099 52.238 -41.400 1.00 17.44 ? 32 ILE A CG1 1 ATOM 192 C CG2 . ILE A 1 24 ? 145.179 53.768 -41.812 1.00 17.79 ? 32 ILE A CG2 1 ATOM 193 C CD1 . ILE A 1 24 ? 146.957 52.212 -39.892 1.00 17.79 ? 32 ILE A CD1 1 ATOM 194 N N . THR A 1 25 ? 149.318 54.219 -43.422 1.00 17.34 ? 33 THR A N 1 ATOM 195 C CA . THR A 1 25 ? 150.764 54.029 -43.486 1.00 17.95 ? 33 THR A CA 1 ATOM 196 C C . THR A 1 25 ? 151.426 55.108 -42.651 1.00 18.61 ? 33 THR A C 1 ATOM 197 O O . THR A 1 25 ? 150.813 56.138 -42.366 1.00 20.43 ? 33 THR A O 1 ATOM 198 C CB . THR A 1 25 ? 151.300 54.094 -44.931 1.00 17.71 ? 33 THR A CB 1 ATOM 199 O OG1 . THR A 1 25 ? 152.650 53.627 -44.944 1.00 18.44 ? 33 THR A OG1 1 ATOM 200 C CG2 . THR A 1 25 ? 151.282 55.518 -45.458 1.00 17.14 ? 33 THR A CG2 1 ATOM 201 N N . GLN A 1 26 ? 152.669 54.875 -42.248 1.00 19.10 ? 34 GLN A N 1 ATOM 202 C CA . GLN A 1 26 ? 153.380 55.849 -41.423 1.00 19.87 ? 34 GLN A CA 1 ATOM 203 C C . GLN A 1 26 ? 153.410 57.220 -42.096 1.00 20.23 ? 34 GLN A C 1 ATOM 204 O O . GLN A 1 26 ? 153.702 57.325 -43.292 1.00 20.85 ? 34 GLN A O 1 ATOM 205 C CB . GLN A 1 26 ? 154.795 55.360 -41.138 1.00 17.61 ? 34 GLN A CB 1 ATOM 206 C CG . GLN A 1 26 ? 155.552 56.260 -40.214 1.00 18.19 ? 34 GLN A CG 1 ATOM 207 C CD . GLN A 1 26 ? 156.695 55.552 -39.529 1.00 19.43 ? 34 GLN A CD 1 ATOM 208 O OE1 . GLN A 1 26 ? 157.808 56.084 -39.456 1.00 19.88 ? 34 GLN A OE1 1 ATOM 209 N NE2 . GLN A 1 26 ? 156.429 54.357 -39.001 1.00 15.05 ? 34 GLN A NE2 1 ATOM 210 N N . GLY A 1 27 ? 153.107 58.264 -41.325 1.00 19.75 ? 35 GLY A N 1 ATOM 211 C CA . GLY A 1 27 ? 153.064 59.603 -41.889 1.00 19.89 ? 35 GLY A CA 1 ATOM 212 C C . GLY A 1 27 ? 154.242 60.533 -41.655 1.00 20.09 ? 35 GLY A C 1 ATOM 213 O O . GLY A 1 27 ? 154.253 61.657 -42.171 1.00 19.69 ? 35 GLY A O 1 ATOM 214 N N . ASP A 1 28 ? 155.229 60.085 -40.886 1.00 20.81 ? 36 ASP A N 1 ATOM 215 C CA . ASP A 1 28 ? 156.399 60.908 -40.597 1.00 20.77 ? 36 ASP A CA 1 ATOM 216 C C . ASP A 1 28 ? 157.633 60.021 -40.534 1.00 21.77 ? 36 ASP A C 1 ATOM 217 O O . ASP A 1 28 ? 157.577 58.829 -40.848 1.00 21.40 ? 36 ASP A O 1 ATOM 218 C CB . ASP A 1 28 ? 156.215 61.631 -39.264 1.00 21.05 ? 36 ASP A CB 1 ATOM 219 C CG . ASP A 1 28 ? 156.239 60.678 -38.080 1.00 24.13 ? 36 ASP A CG 1 ATOM 220 O OD1 . ASP A 1 28 ? 155.795 59.519 -38.244 1.00 22.46 ? 36 ASP A OD1 1 ATOM 221 O OD2 . ASP A 1 28 ? 156.693 61.086 -36.988 1.00 26.17 ? 36 ASP A OD2 1 ATOM 222 N N . LEU A 1 29 ? 158.743 60.606 -40.106 1.00 22.95 ? 37 LEU A N 1 ATOM 223 C CA . LEU A 1 29 ? 160.002 59.892 -40.010 1.00 23.45 ? 37 LEU A CA 1 ATOM 224 C C . LEU A 1 29 ? 160.079 58.920 -38.835 1.00 24.21 ? 37 LEU A C 1 ATOM 225 O O . LEU A 1 29 ? 160.504 57.777 -39.004 1.00 24.49 ? 37 LEU A O 1 ATOM 226 C CB . LEU A 1 29 ? 161.146 60.905 -39.904 1.00 23.60 ? 37 LEU A CB 1 ATOM 227 C CG . LEU A 1 29 ? 162.568 60.398 -40.148 1.00 23.63 ? 37 LEU A CG 1 ATOM 228 C CD1 . LEU A 1 29 ? 162.691 59.891 -41.573 1.00 24.34 ? 37 LEU A CD1 1 ATOM 229 C CD2 . LEU A 1 29 ? 163.552 61.526 -39.910 1.00 23.99 ? 37 LEU A CD2 1 ATOM 230 N N . VAL A 1 30 ? 159.656 59.370 -37.654 1.00 25.41 ? 38 VAL A N 1 ATOM 231 C CA . VAL A 1 30 ? 159.742 58.554 -36.437 1.00 26.49 ? 38 VAL A CA 1 ATOM 232 C C . VAL A 1 30 ? 158.523 57.749 -35.985 1.00 26.73 ? 38 VAL A C 1 ATOM 233 O O . VAL A 1 30 ? 158.620 56.958 -35.049 1.00 27.91 ? 38 VAL A O 1 ATOM 234 C CB . VAL A 1 30 ? 160.169 59.419 -35.251 1.00 26.89 ? 38 VAL A CB 1 ATOM 235 C CG1 . VAL A 1 30 ? 161.452 60.153 -35.591 1.00 25.77 ? 38 VAL A CG1 1 ATOM 236 C CG2 . VAL A 1 30 ? 159.057 60.399 -34.905 1.00 26.82 ? 38 VAL A CG2 1 ATOM 237 N N . GLY A 1 31 ? 157.376 57.964 -36.612 1.00 27.49 ? 39 GLY A N 1 ATOM 238 C CA . GLY A 1 31 ? 156.200 57.204 -36.229 1.00 27.98 ? 39 GLY A CA 1 ATOM 239 C C . GLY A 1 31 ? 155.148 57.886 -35.365 1.00 28.67 ? 39 GLY A C 1 ATOM 240 O O . GLY A 1 31 ? 154.304 57.204 -34.782 1.00 27.25 ? 39 GLY A O 1 ATOM 241 N N . ARG A 1 32 ? 155.176 59.211 -35.266 1.00 29.03 ? 40 ARG A N 1 ATOM 242 C CA . ARG A 1 32 ? 154.173 59.902 -34.468 1.00 29.71 ? 40 ARG A CA 1 ATOM 243 C C . ARG A 1 32 ? 153.080 60.447 -35.377 1.00 29.34 ? 40 ARG A C 1 ATOM 244 O O . ARG A 1 32 ? 152.302 61.319 -34.973 1.00 29.67 ? 40 ARG A O 1 ATOM 245 C CB . ARG A 1 32 ? 154.798 61.052 -33.685 1.00 32.95 ? 40 ARG A CB 1 ATOM 246 C CG . ARG A 1 32 ? 155.926 60.641 -32.767 1.00 39.22 ? 40 ARG A CG 1 ATOM 247 C CD . ARG A 1 32 ? 156.364 61.805 -31.905 1.00 44.36 ? 40 ARG A CD 1 ATOM 248 N NE . ARG A 1 32 ? 155.272 62.260 -31.051 1.00 50.73 ? 40 ARG A NE 1 ATOM 249 C CZ . ARG A 1 32 ? 155.399 63.182 -30.101 1.00 53.38 ? 40 ARG A CZ 1 ATOM 250 N NH1 . ARG A 1 32 ? 156.580 63.753 -29.885 1.00 54.13 ? 40 ARG A NH1 1 ATOM 251 N NH2 . ARG A 1 32 ? 154.349 63.523 -29.359 1.00 54.10 ? 40 ARG A NH2 1 ATOM 252 N N . ALA A 1 33 ? 153.023 59.933 -36.604 1.00 27.68 ? 41 ALA A N 1 ATOM 253 C CA . ALA A 1 33 ? 152.015 60.369 -37.566 1.00 26.27 ? 41 ALA A CA 1 ATOM 254 C C . ALA A 1 33 ? 151.545 59.217 -38.446 1.00 25.66 ? 41 ALA A C 1 ATOM 255 O O . ALA A 1 33 ? 152.230 58.205 -38.602 1.00 26.07 ? 41 ALA A O 1 ATOM 256 C CB . ALA A 1 33 ? 152.560 61.498 -38.431 1.00 24.87 ? 41 ALA A CB 1 ATOM 257 N N . MET A 1 34 ? 150.362 59.382 -39.019 1.00 25.18 ? 42 MET A N 1 ATOM 258 C CA . MET A 1 34 ? 149.769 58.369 -39.885 1.00 25.67 ? 42 MET A CA 1 ATOM 259 C C . MET A 1 34 ? 149.032 58.999 -41.059 1.00 25.01 ? 42 MET A C 1 ATOM 260 O O . MET A 1 34 ? 148.348 60.016 -40.911 1.00 25.46 ? 42 MET A O 1 ATOM 261 C CB . MET A 1 34 ? 148.771 57.523 -39.096 1.00 27.54 ? 42 MET A CB 1 ATOM 262 C CG . MET A 1 34 ? 149.379 56.392 -38.304 1.00 31.21 ? 42 MET A CG 1 ATOM 263 S SD . MET A 1 34 ? 149.738 55.011 -39.380 1.00 32.41 ? 42 MET A SD 1 ATOM 264 C CE . MET A 1 34 ? 150.567 53.946 -38.226 1.00 34.36 ? 42 MET A CE 1 ATOM 265 N N . ILE A 1 35 ? 149.181 58.404 -42.234 1.00 22.75 ? 43 ILE A N 1 ATOM 266 C CA . ILE A 1 35 ? 148.463 58.895 -43.393 1.00 20.11 ? 43 ILE A CA 1 ATOM 267 C C . ILE A 1 35 ? 147.239 57.982 -43.537 1.00 21.51 ? 43 ILE A C 1 ATOM 268 O O . ILE A 1 35 ? 147.390 56.782 -43.781 1.00 22.08 ? 43 ILE A O 1 ATOM 269 C CB . ILE A 1 35 ? 149.326 58.810 -44.663 1.00 18.63 ? 43 ILE A CB 1 ATOM 270 C CG1 . ILE A 1 35 ? 150.512 59.772 -44.549 1.00 17.28 ? 43 ILE A CG1 1 ATOM 271 C CG2 . ILE A 1 35 ? 148.490 59.135 -45.884 1.00 16.12 ? 43 ILE A CG2 1 ATOM 272 C CD1 . ILE A 1 35 ? 151.393 59.812 -45.779 1.00 15.25 ? 43 ILE A CD1 1 ATOM 273 N N . ILE A 1 36 ? 146.040 58.539 -43.341 1.00 22.36 ? 44 ILE A N 1 ATOM 274 C CA . ILE A 1 36 ? 144.794 57.778 -43.478 1.00 23.01 ? 44 ILE A CA 1 ATOM 275 C C . ILE A 1 36 ? 144.241 58.017 -44.890 1.00 23.77 ? 44 ILE A C 1 ATOM 276 O O . ILE A 1 36 ? 144.056 59.174 -45.302 1.00 23.49 ? 44 ILE A O 1 ATOM 277 C CB . ILE A 1 36 ? 143.710 58.231 -42.459 1.00 22.56 ? 44 ILE A CB 1 ATOM 278 C CG1 . ILE A 1 36 ? 144.261 58.200 -41.029 1.00 22.47 ? 44 ILE A CG1 1 ATOM 279 C CG2 . ILE A 1 36 ? 142.481 57.336 -42.588 1.00 20.59 ? 44 ILE A CG2 1 ATOM 280 C CD1 . ILE A 1 36 ? 144.819 56.870 -40.599 1.00 21.69 ? 44 ILE A CD1 1 ATOM 281 N N . SER A 1 37 ? 143.980 56.936 -45.626 1.00 23.56 ? 45 SER A N 1 ATOM 282 C CA . SER A 1 37 ? 143.462 57.056 -46.986 1.00 24.12 ? 45 SER A CA 1 ATOM 283 C C . SER A 1 37 ? 142.201 56.228 -47.213 1.00 24.83 ? 45 SER A C 1 ATOM 284 O O . SER A 1 37 ? 142.058 55.126 -46.669 1.00 25.48 ? 45 SER A O 1 ATOM 285 C CB . SER A 1 37 ? 144.524 56.616 -48.001 1.00 23.11 ? 45 SER A CB 1 ATOM 286 O OG . SER A 1 37 ? 145.708 57.382 -47.886 1.00 24.02 ? 45 SER A OG 1 ATOM 287 N N . TRP A 1 38 ? 141.288 56.758 -48.024 1.00 24.97 ? 46 TRP A N 1 ATOM 288 C CA . TRP A 1 38 ? 140.055 56.042 -48.346 1.00 25.19 ? 46 TRP A CA 1 ATOM 289 C C . TRP A 1 38 ? 139.393 56.576 -49.619 1.00 25.51 ? 46 TRP A C 1 ATOM 290 O O . TRP A 1 38 ? 139.846 57.568 -50.205 1.00 25.63 ? 46 TRP A O 1 ATOM 291 C CB . TRP A 1 38 ? 139.080 56.088 -47.158 1.00 24.00 ? 46 TRP A CB 1 ATOM 292 C CG . TRP A 1 38 ? 138.440 57.420 -46.887 1.00 22.13 ? 46 TRP A CG 1 ATOM 293 C CD1 . TRP A 1 38 ? 137.158 57.792 -47.198 1.00 21.57 ? 46 TRP A CD1 1 ATOM 294 C CD2 . TRP A 1 38 ? 139.026 58.532 -46.196 1.00 20.29 ? 46 TRP A CD2 1 ATOM 295 N NE1 . TRP A 1 38 ? 136.912 59.066 -46.734 1.00 21.42 ? 46 TRP A NE1 1 ATOM 296 C CE2 . TRP A 1 38 ? 138.040 59.543 -46.117 1.00 20.30 ? 46 TRP A CE2 1 ATOM 297 C CE3 . TRP A 1 38 ? 140.285 58.773 -45.638 1.00 18.70 ? 46 TRP A CE3 1 ATOM 298 C CZ2 . TRP A 1 38 ? 138.279 60.776 -45.497 1.00 18.94 ? 46 TRP A CZ2 1 ATOM 299 C CZ3 . TRP A 1 38 ? 140.520 60.004 -45.022 1.00 18.82 ? 46 TRP A CZ3 1 ATOM 300 C CH2 . TRP A 1 38 ? 139.522 60.986 -44.958 1.00 16.65 ? 46 TRP A CH2 1 ATOM 301 N N . VAL A 1 39 ? 138.334 55.901 -50.055 1.00 25.02 ? 47 VAL A N 1 ATOM 302 C CA . VAL A 1 39 ? 137.620 56.305 -51.253 1.00 24.56 ? 47 VAL A CA 1 ATOM 303 C C . VAL A 1 39 ? 136.116 56.341 -51.018 1.00 25.38 ? 47 VAL A C 1 ATOM 304 O O . VAL A 1 39 ? 135.577 55.521 -50.279 1.00 27.15 ? 47 VAL A O 1 ATOM 305 C CB . VAL A 1 39 ? 137.877 55.321 -52.410 1.00 23.53 ? 47 VAL A CB 1 ATOM 306 C CG1 . VAL A 1 39 ? 137.164 55.797 -53.666 1.00 23.48 ? 47 VAL A CG1 1 ATOM 307 C CG2 . VAL A 1 39 ? 139.354 55.181 -52.656 1.00 21.97 ? 47 VAL A CG2 1 ATOM 308 N N . THR A 1 40 ? 135.442 57.300 -51.638 1.00 24.62 ? 48 THR A N 1 ATOM 309 C CA . THR A 1 40 ? 133.995 57.389 -51.534 1.00 24.25 ? 48 THR A CA 1 ATOM 310 C C . THR A 1 40 ? 133.504 57.387 -52.980 1.00 25.48 ? 48 THR A C 1 ATOM 311 O O . THR A 1 40 ? 134.096 58.047 -53.836 1.00 25.38 ? 48 THR A O 1 ATOM 312 C CB . THR A 1 40 ? 133.559 58.665 -50.814 1.00 22.56 ? 48 THR A CB 1 ATOM 313 O OG1 . THR A 1 40 ? 134.202 59.795 -51.408 1.00 23.63 ? 48 THR A OG1 1 ATOM 314 C CG2 . THR A 1 40 ? 133.931 58.594 -49.351 1.00 22.36 ? 48 THR A CG2 1 ATOM 315 N N . MET A 1 41 ? 132.436 56.640 -53.251 1.00 25.97 ? 49 MET A N 1 ATOM 316 C CA . MET A 1 41 ? 131.914 56.512 -54.603 1.00 26.92 ? 49 MET A CA 1 ATOM 317 C C . MET A 1 41 ? 130.692 57.339 -54.947 1.00 27.56 ? 49 MET A C 1 ATOM 318 O O . MET A 1 41 ? 130.514 57.731 -56.098 1.00 28.25 ? 49 MET A O 1 ATOM 319 C CB . MET A 1 41 ? 131.584 55.050 -54.888 1.00 28.87 ? 49 MET A CB 1 ATOM 320 C CG . MET A 1 41 ? 132.777 54.135 -54.905 1.00 32.20 ? 49 MET A CG 1 ATOM 321 S SD . MET A 1 41 ? 133.867 54.507 -56.276 1.00 36.14 ? 49 MET A SD 1 ATOM 322 C CE . MET A 1 41 ? 134.894 53.000 -56.273 1.00 35.38 ? 49 MET A CE 1 ATOM 323 N N . ASP A 1 42 ? 129.847 57.606 -53.964 1.00 27.94 ? 50 ASP A N 1 ATOM 324 C CA . ASP A 1 42 ? 128.623 58.343 -54.232 1.00 28.63 ? 50 ASP A CA 1 ATOM 325 C C . ASP A 1 42 ? 128.760 59.849 -54.373 1.00 28.04 ? 50 ASP A C 1 ATOM 326 O O . ASP A 1 42 ? 128.040 60.474 -55.146 1.00 28.26 ? 50 ASP A O 1 ATOM 327 C CB . ASP A 1 42 ? 127.581 57.985 -53.174 1.00 29.99 ? 50 ASP A CB 1 ATOM 328 C CG . ASP A 1 42 ? 127.272 56.507 -53.167 1.00 30.37 ? 50 ASP A CG 1 ATOM 329 O OD1 . ASP A 1 42 ? 127.071 55.954 -54.270 1.00 30.38 ? 50 ASP A OD1 1 ATOM 330 O OD2 . ASP A 1 42 ? 127.241 55.901 -52.074 1.00 33.65 ? 50 ASP A OD2 1 ATOM 331 N N . GLU A 1 43 ? 129.674 60.438 -53.625 1.00 27.99 ? 51 GLU A N 1 ATOM 332 C CA . GLU A 1 43 ? 129.891 61.868 -53.728 1.00 28.16 ? 51 GLU A CA 1 ATOM 333 C C . GLU A 1 43 ? 131.140 62.232 -52.964 1.00 28.18 ? 51 GLU A C 1 ATOM 334 O O . GLU A 1 43 ? 131.567 61.495 -52.083 1.00 29.59 ? 51 GLU A O 1 ATOM 335 C CB . GLU A 1 43 ? 128.692 62.650 -53.189 1.00 28.15 ? 51 GLU A CB 1 ATOM 336 C CG . GLU A 1 43 ? 128.391 62.456 -51.721 1.00 29.30 ? 51 GLU A CG 1 ATOM 337 C CD . GLU A 1 43 ? 127.433 63.518 -51.209 1.00 30.72 ? 51 GLU A CD 1 ATOM 338 O OE1 . GLU A 1 43 ? 127.897 64.548 -50.669 1.00 29.83 ? 51 GLU A OE1 1 ATOM 339 O OE2 . GLU A 1 43 ? 126.208 63.333 -51.365 1.00 31.45 ? 51 GLU A OE2 1 ATOM 340 N N . PRO A 1 44 ? 131.746 63.378 -53.288 1.00 27.77 ? 52 PRO A N 1 ATOM 341 C CA . PRO A 1 44 ? 132.963 63.812 -52.606 1.00 28.58 ? 52 PRO A CA 1 ATOM 342 C C . PRO A 1 44 ? 133.047 63.415 -51.124 1.00 29.33 ? 52 PRO A C 1 ATOM 343 O O . PRO A 1 44 ? 133.838 62.541 -50.757 1.00 30.27 ? 52 PRO A O 1 ATOM 344 C CB . PRO A 1 44 ? 132.946 65.316 -52.840 1.00 28.36 ? 52 PRO A CB 1 ATOM 345 C CG . PRO A 1 44 ? 132.418 65.385 -54.235 1.00 27.01 ? 52 PRO A CG 1 ATOM 346 C CD . PRO A 1 44 ? 131.250 64.435 -54.186 1.00 26.98 ? 52 PRO A CD 1 ATOM 347 N N . GLY A 1 45 ? 132.229 64.032 -50.278 1.00 29.38 ? 53 GLY A N 1 ATOM 348 C CA . GLY A 1 45 ? 132.270 63.704 -48.865 1.00 29.28 ? 53 GLY A CA 1 ATOM 349 C C . GLY A 1 45 ? 133.351 64.509 -48.168 1.00 30.31 ? 53 GLY A C 1 ATOM 350 O O . GLY A 1 45 ? 134.096 65.237 -48.831 1.00 30.38 ? 53 GLY A O 1 ATOM 351 N N . SER A 1 46 ? 133.451 64.387 -46.844 1.00 30.74 ? 54 SER A N 1 ATOM 352 C CA . SER A 1 46 ? 134.460 65.138 -46.099 1.00 31.88 ? 54 SER A CA 1 ATOM 353 C C . SER A 1 46 ? 135.787 64.403 -46.057 1.00 32.61 ? 54 SER A C 1 ATOM 354 O O . SER A 1 46 ? 135.825 63.172 -46.090 1.00 32.69 ? 54 SER A O 1 ATOM 355 C CB . SER A 1 46 ? 134.000 65.401 -44.663 1.00 31.45 ? 54 SER A CB 1 ATOM 356 O OG . SER A 1 46 ? 134.964 66.174 -43.963 1.00 31.62 ? 54 SER A OG 1 ATOM 357 N N . SER A 1 47 ? 136.875 65.163 -45.992 1.00 32.53 ? 55 SER A N 1 ATOM 358 C CA . SER A 1 47 ? 138.206 64.574 -45.926 1.00 32.89 ? 55 SER A CA 1 ATOM 359 C C . SER A 1 47 ? 138.694 64.703 -44.492 1.00 33.44 ? 55 SER A C 1 ATOM 360 O O . SER A 1 47 ? 139.897 64.778 -44.236 1.00 34.33 ? 55 SER A O 1 ATOM 361 C CB . SER A 1 47 ? 139.175 65.298 -46.866 1.00 32.08 ? 55 SER A CB 1 ATOM 362 O OG . SER A 1 47 ? 138.780 65.159 -48.216 1.00 32.92 ? 55 SER A OG 1 ATOM 363 N N . ALA A 1 48 ? 137.750 64.740 -43.558 1.00 32.25 ? 56 ALA A N 1 ATOM 364 C CA . ALA A 1 48 ? 138.092 64.862 -42.151 1.00 31.15 ? 56 ALA A CA 1 ATOM 365 C C . ALA A 1 48 ? 138.197 63.492 -41.508 1.00 30.23 ? 56 ALA A C 1 ATOM 366 O O . ALA A 1 48 ? 137.532 62.544 -41.921 1.00 29.67 ? 56 ALA A O 1 ATOM 367 C CB . ALA A 1 48 ? 137.046 65.695 -41.423 1.00 30.52 ? 56 ALA A CB 1 ATOM 368 N N . VAL A 1 49 ? 139.041 63.394 -40.493 1.00 30.01 ? 57 VAL A N 1 ATOM 369 C CA . VAL A 1 49 ? 139.220 62.149 -39.769 1.00 30.70 ? 57 VAL A CA 1 ATOM 370 C C . VAL A 1 49 ? 139.130 62.480 -38.285 1.00 31.06 ? 57 VAL A C 1 ATOM 371 O O . VAL A 1 49 ? 139.807 63.391 -37.806 1.00 31.04 ? 57 VAL A O 1 ATOM 372 C CB . VAL A 1 49 ? 140.599 61.512 -40.068 1.00 31.18 ? 57 VAL A CB 1 ATOM 373 C CG1 . VAL A 1 49 ? 140.737 60.186 -39.324 1.00 30.26 ? 57 VAL A CG1 1 ATOM 374 C CG2 . VAL A 1 49 ? 140.761 61.301 -41.569 1.00 31.63 ? 57 VAL A CG2 1 ATOM 375 N N . ARG A 1 50 ? 138.270 61.761 -37.571 1.00 31.64 ? 58 ARG A N 1 ATOM 376 C CA . ARG A 1 50 ? 138.098 61.966 -36.139 1.00 32.52 ? 58 ARG A CA 1 ATOM 377 C C . ARG A 1 50 ? 138.832 60.815 -35.470 1.00 32.05 ? 58 ARG A C 1 ATOM 378 O O . ARG A 1 50 ? 138.652 59.656 -35.849 1.00 31.60 ? 58 ARG A O 1 ATOM 379 C CB . ARG A 1 50 ? 136.607 61.955 -35.786 1.00 34.69 ? 58 ARG A CB 1 ATOM 380 C CG . ARG A 1 50 ? 136.273 62.224 -34.319 1.00 36.48 ? 58 ARG A CG 1 ATOM 381 C CD . ARG A 1 50 ? 134.833 62.727 -34.180 1.00 38.77 ? 58 ARG A CD 1 ATOM 382 N NE . ARG A 1 50 ? 133.858 61.844 -34.825 1.00 40.77 ? 58 ARG A NE 1 ATOM 383 C CZ . ARG A 1 50 ? 132.734 62.270 -35.400 1.00 41.28 ? 58 ARG A CZ 1 ATOM 384 N NH1 . ARG A 1 50 ? 132.448 63.566 -35.413 1.00 41.86 ? 58 ARG A NH1 1 ATOM 385 N NH2 . ARG A 1 50 ? 131.898 61.408 -35.967 1.00 40.66 ? 58 ARG A NH2 1 ATOM 386 N N . TYR A 1 51 ? 139.673 61.132 -34.491 1.00 32.06 ? 59 TYR A N 1 ATOM 387 C CA . TYR A 1 51 ? 140.445 60.100 -33.815 1.00 32.19 ? 59 TYR A CA 1 ATOM 388 C C . TYR A 1 51 ? 140.648 60.401 -32.338 1.00 33.57 ? 59 TYR A C 1 ATOM 389 O O . TYR A 1 51 ? 140.609 61.563 -31.923 1.00 33.23 ? 59 TYR A O 1 ATOM 390 C CB . TYR A 1 51 ? 141.810 59.956 -34.484 1.00 30.78 ? 59 TYR A CB 1 ATOM 391 C CG . TYR A 1 51 ? 142.657 61.204 -34.396 1.00 29.02 ? 59 TYR A CG 1 ATOM 392 C CD1 . TYR A 1 51 ? 142.416 62.296 -35.225 1.00 27.99 ? 59 TYR A CD1 1 ATOM 393 C CD2 . TYR A 1 51 ? 143.688 61.299 -33.464 1.00 28.77 ? 59 TYR A CD2 1 ATOM 394 C CE1 . TYR A 1 51 ? 143.183 63.452 -35.129 1.00 27.94 ? 59 TYR A CE1 1 ATOM 395 C CE2 . TYR A 1 51 ? 144.459 62.452 -33.359 1.00 28.57 ? 59 TYR A CE2 1 ATOM 396 C CZ . TYR A 1 51 ? 144.203 63.521 -34.193 1.00 28.29 ? 59 TYR A CZ 1 ATOM 397 O OH . TYR A 1 51 ? 144.977 64.650 -34.090 1.00 29.46 ? 59 TYR A OH 1 ATOM 398 N N . TRP A 1 52 ? 140.887 59.346 -31.559 1.00 34.85 ? 60 TRP A N 1 ATOM 399 C CA . TRP A 1 52 ? 141.102 59.467 -30.119 1.00 35.63 ? 60 TRP A CA 1 ATOM 400 C C . TRP A 1 52 ? 141.768 58.194 -29.591 1.00 36.86 ? 60 TRP A C 1 ATOM 401 O O . TRP A 1 52 ? 141.623 57.123 -30.187 1.00 35.13 ? 60 TRP A O 1 ATOM 402 C CB . TRP A 1 52 ? 139.755 59.711 -29.411 1.00 34.33 ? 60 TRP A CB 1 ATOM 403 C CG . TRP A 1 52 ? 138.755 58.584 -29.557 1.00 32.81 ? 60 TRP A CG 1 ATOM 404 C CD1 . TRP A 1 52 ? 138.579 57.529 -28.704 1.00 33.72 ? 60 TRP A CD1 1 ATOM 405 C CD2 . TRP A 1 52 ? 137.827 58.385 -30.632 1.00 32.01 ? 60 TRP A CD2 1 ATOM 406 N NE1 . TRP A 1 52 ? 137.601 56.685 -29.181 1.00 32.85 ? 60 TRP A NE1 1 ATOM 407 C CE2 . TRP A 1 52 ? 137.123 57.186 -30.362 1.00 32.17 ? 60 TRP A CE2 1 ATOM 408 C CE3 . TRP A 1 52 ? 137.522 59.101 -31.796 1.00 31.67 ? 60 TRP A CE3 1 ATOM 409 C CZ2 . TRP A 1 52 ? 136.133 56.686 -31.213 1.00 31.90 ? 60 TRP A CZ2 1 ATOM 410 C CZ3 . TRP A 1 52 ? 136.532 58.603 -32.646 1.00 33.28 ? 60 TRP A CZ3 1 ATOM 411 C CH2 . TRP A 1 52 ? 135.850 57.405 -32.347 1.00 32.99 ? 60 TRP A CH2 1 ATOM 412 N N . SER A 1 53 ? 142.499 58.313 -28.483 1.00 39.54 ? 61 SER A N 1 ATOM 413 C CA . SER A 1 53 ? 143.179 57.163 -27.887 1.00 43.65 ? 61 SER A CA 1 ATOM 414 C C . SER A 1 53 ? 142.289 56.491 -26.852 1.00 47.66 ? 61 SER A C 1 ATOM 415 O O . SER A 1 53 ? 141.304 57.079 -26.411 1.00 48.31 ? 61 SER A O 1 ATOM 416 C CB . SER A 1 53 ? 144.493 57.599 -27.234 1.00 42.59 ? 61 SER A CB 1 ATOM 417 O OG . SER A 1 53 ? 144.283 58.643 -26.304 1.00 41.02 ? 61 SER A OG 1 ATOM 418 N N . GLU A 1 54 ? 142.633 55.261 -26.470 1.00 52.51 ? 62 GLU A N 1 ATOM 419 C CA . GLU A 1 54 ? 141.856 54.506 -25.485 1.00 56.65 ? 62 GLU A CA 1 ATOM 420 C C . GLU A 1 54 ? 141.757 55.225 -24.144 1.00 59.51 ? 62 GLU A C 1 ATOM 421 O O . GLU A 1 54 ? 140.691 55.262 -23.521 1.00 60.40 ? 62 GLU A O 1 ATOM 422 C CB . GLU A 1 54 ? 142.471 53.125 -25.269 1.00 57.14 ? 62 GLU A CB 1 ATOM 423 C CG . GLU A 1 54 ? 142.150 52.131 -26.364 1.00 60.28 ? 62 GLU A CG 1 ATOM 424 C CD . GLU A 1 54 ? 141.799 50.759 -25.810 1.00 62.32 ? 62 GLU A CD 1 ATOM 425 O OE1 . GLU A 1 54 ? 142.684 50.117 -25.203 1.00 62.84 ? 62 GLU A OE1 1 ATOM 426 O OE2 . GLU A 1 54 ? 140.635 50.327 -25.978 1.00 63.24 ? 62 GLU A OE2 1 ATOM 427 N N . LYS A 1 55 ? 142.882 55.779 -23.703 1.00 62.37 ? 63 LYS A N 1 ATOM 428 C CA . LYS A 1 55 ? 142.957 56.515 -22.445 1.00 65.32 ? 63 LYS A CA 1 ATOM 429 C C . LYS A 1 55 ? 142.201 57.843 -22.545 1.00 67.20 ? 63 LYS A C 1 ATOM 430 O O . LYS A 1 55 ? 140.997 57.901 -22.274 1.00 68.24 ? 63 LYS A O 1 ATOM 431 C CB . LYS A 1 55 ? 144.425 56.761 -22.089 1.00 66.18 ? 63 LYS A CB 1 ATOM 432 C CG . LYS A 1 55 ? 145.322 57.046 -23.292 1.00 67.25 ? 63 LYS A CG 1 ATOM 433 C CD . LYS A 1 55 ? 145.990 58.411 -23.185 1.00 68.35 ? 63 LYS A CD 1 ATOM 434 C CE . LYS A 1 55 ? 146.937 58.658 -24.355 1.00 68.82 ? 63 LYS A CE 1 ATOM 435 N NZ . LYS A 1 55 ? 148.036 57.646 -24.420 1.00 68.82 ? 63 LYS A NZ 1 ATOM 436 N N . ASN A 1 56 ? 142.913 58.903 -22.927 1.00 68.96 ? 64 ASN A N 1 ATOM 437 C CA . ASN A 1 56 ? 142.325 60.237 -23.098 1.00 70.49 ? 64 ASN A CA 1 ATOM 438 C C . ASN A 1 56 ? 141.241 60.175 -24.189 1.00 69.56 ? 64 ASN A C 1 ATOM 439 O O . ASN A 1 56 ? 141.552 60.181 -25.388 1.00 70.66 ? 64 ASN A O 1 ATOM 440 C CB . ASN A 1 56 ? 143.428 61.232 -23.516 1.00 73.37 ? 64 ASN A CB 1 ATOM 441 C CG . ASN A 1 56 ? 142.922 62.673 -23.662 1.00 75.58 ? 64 ASN A CG 1 ATOM 442 O OD1 . ASN A 1 56 ? 143.561 63.498 -24.329 1.00 75.60 ? 64 ASN A OD1 1 ATOM 443 N ND2 . ASN A 1 56 ? 141.791 62.983 -23.028 1.00 76.23 ? 64 ASN A ND2 1 ATOM 444 N N . GLY A 1 57 ? 139.975 60.119 -23.783 1.00 67.12 ? 65 GLY A N 1 ATOM 445 C CA . GLY A 1 57 ? 138.905 60.051 -24.766 1.00 64.84 ? 65 GLY A CA 1 ATOM 446 C C . GLY A 1 57 ? 138.760 61.297 -25.630 1.00 63.32 ? 65 GLY A C 1 ATOM 447 O O . GLY A 1 57 ? 137.843 61.377 -26.453 1.00 63.94 ? 65 GLY A O 1 ATOM 448 N N . ARG A 1 58 ? 139.664 62.260 -25.452 1.00 60.75 ? 66 ARG A N 1 ATOM 449 C CA . ARG A 1 58 ? 139.636 63.521 -26.195 1.00 58.26 ? 66 ARG A CA 1 ATOM 450 C C . ARG A 1 58 ? 139.608 63.305 -27.704 1.00 55.66 ? 66 ARG A C 1 ATOM 451 O O . ARG A 1 58 ? 140.615 62.932 -28.306 1.00 55.63 ? 66 ARG A O 1 ATOM 452 C CB . ARG A 1 58 ? 140.855 64.367 -25.820 1.00 59.89 ? 66 ARG A CB 1 ATOM 453 C CG . ARG A 1 58 ? 140.764 65.842 -26.202 1.00 61.73 ? 66 ARG A CG 1 ATOM 454 C CD . ARG A 1 58 ? 141.965 66.599 -25.630 1.00 65.30 ? 66 ARG A CD 1 ATOM 455 N NE . ARG A 1 58 ? 141.728 68.034 -25.465 1.00 68.43 ? 66 ARG A NE 1 ATOM 456 C CZ . ARG A 1 58 ? 141.622 68.905 -26.467 1.00 70.05 ? 66 ARG A CZ 1 ATOM 457 N NH1 . ARG A 1 58 ? 141.733 68.494 -27.725 1.00 70.24 ? 66 ARG A NH1 1 ATOM 458 N NH2 . ARG A 1 58 ? 141.402 70.191 -26.212 1.00 70.27 ? 66 ARG A NH2 1 ATOM 459 N N . LYS A 1 59 ? 138.454 63.545 -28.315 1.00 52.16 ? 67 LYS A N 1 ATOM 460 C CA . LYS A 1 59 ? 138.316 63.363 -29.751 1.00 49.08 ? 67 LYS A CA 1 ATOM 461 C C . LYS A 1 59 ? 138.793 64.581 -30.528 1.00 47.57 ? 67 LYS A C 1 ATOM 462 O O . LYS A 1 59 ? 138.422 65.709 -30.215 1.00 48.05 ? 67 LYS A O 1 ATOM 463 C CB . LYS A 1 59 ? 136.861 63.066 -30.106 1.00 48.15 ? 67 LYS A CB 1 ATOM 464 C CG . LYS A 1 59 ? 136.332 61.784 -29.490 1.00 47.10 ? 67 LYS A CG 1 ATOM 465 C CD . LYS A 1 59 ? 134.979 61.437 -30.064 1.00 46.36 ? 67 LYS A CD 1 ATOM 466 C CE . LYS A 1 59 ? 134.448 60.146 -29.478 1.00 47.03 ? 67 LYS A CE 1 ATOM 467 N NZ . LYS A 1 59 ? 133.211 59.715 -30.188 1.00 49.43 ? 67 LYS A NZ 1 ATOM 468 N N . ARG A 1 60 ? 139.626 64.345 -31.536 1.00 45.60 ? 68 ARG A N 1 ATOM 469 C CA . ARG A 1 60 ? 140.143 65.425 -32.365 1.00 43.24 ? 68 ARG A CA 1 ATOM 470 C C . ARG A 1 60 ? 139.788 65.194 -33.827 1.00 41.07 ? 68 ARG A C 1 ATOM 471 O O . ARG A 1 60 ? 139.366 64.100 -34.217 1.00 39.98 ? 68 ARG A O 1 ATOM 472 C CB . ARG A 1 60 ? 141.660 65.537 -32.223 1.00 45.10 ? 68 ARG A CB 1 ATOM 473 C CG . ARG A 1 60 ? 142.133 65.930 -30.837 1.00 49.08 ? 68 ARG A CG 1 ATOM 474 C CD . ARG A 1 60 ? 143.596 66.356 -30.874 1.00 53.66 ? 68 ARG A CD 1 ATOM 475 N NE . ARG A 1 60 ? 144.126 66.683 -29.551 1.00 57.97 ? 68 ARG A NE 1 ATOM 476 C CZ . ARG A 1 60 ? 144.357 65.786 -28.594 1.00 60.62 ? 68 ARG A CZ 1 ATOM 477 N NH1 . ARG A 1 60 ? 144.105 64.499 -28.814 1.00 61.42 ? 68 ARG A NH1 1 ATOM 478 N NH2 . ARG A 1 60 ? 144.840 66.171 -27.415 1.00 61.29 ? 68 ARG A NH2 1 ATOM 479 N N . ILE A 1 61 ? 139.961 66.234 -34.633 1.00 38.57 ? 69 ILE A N 1 ATOM 480 C CA . ILE A 1 61 ? 139.665 66.151 -36.050 1.00 37.08 ? 69 ILE A CA 1 ATOM 481 C C . ILE A 1 61 ? 140.792 66.729 -36.896 1.00 36.70 ? 69 ILE A C 1 ATOM 482 O O . ILE A 1 61 ? 141.243 67.847 -36.662 1.00 36.44 ? 69 ILE A O 1 ATOM 483 C CB . ILE A 1 61 ? 138.363 66.897 -36.378 1.00 36.59 ? 69 ILE A CB 1 ATOM 484 C CG1 . ILE A 1 61 ? 137.168 66.073 -35.898 1.00 37.47 ? 69 ILE A CG1 1 ATOM 485 C CG2 . ILE A 1 61 ? 138.266 67.155 -37.871 1.00 37.23 ? 69 ILE A CG2 1 ATOM 486 C CD1 . ILE A 1 61 ? 135.822 66.716 -36.168 1.00 37.66 ? 69 ILE A CD1 1 ATOM 487 N N . ALA A 1 62 ? 141.248 65.953 -37.875 1.00 35.67 ? 70 ALA A N 1 ATOM 488 C CA . ALA A 1 62 ? 142.304 66.392 -38.779 1.00 34.20 ? 70 ALA A CA 1 ATOM 489 C C . ALA A 1 62 ? 141.698 66.431 -40.181 1.00 34.03 ? 70 ALA A C 1 ATOM 490 O O . ALA A 1 62 ? 141.025 65.486 -40.589 1.00 32.88 ? 70 ALA A O 1 ATOM 491 C CB . ALA A 1 62 ? 143.469 65.425 -38.725 1.00 34.48 ? 70 ALA A CB 1 ATOM 492 N N . LYS A 1 63 ? 141.929 67.524 -40.906 1.00 35.04 ? 71 LYS A N 1 ATOM 493 C CA . LYS A 1 63 ? 141.381 67.693 -42.251 1.00 36.22 ? 71 LYS A CA 1 ATOM 494 C C . LYS A 1 63 ? 142.429 67.403 -43.335 1.00 34.97 ? 71 LYS A C 1 ATOM 495 O O . LYS A 1 63 ? 143.535 67.942 -43.302 1.00 35.22 ? 71 LYS A O 1 ATOM 496 C CB . LYS A 1 63 ? 140.836 69.122 -42.409 1.00 39.44 ? 71 LYS A CB 1 ATOM 497 C CG . LYS A 1 63 ? 139.622 69.260 -43.347 1.00 46.83 ? 71 LYS A CG 1 ATOM 498 C CD . LYS A 1 63 ? 139.923 68.854 -44.813 1.00 50.73 ? 71 LYS A CD 1 ATOM 499 C CE . LYS A 1 63 ? 138.700 69.009 -45.760 1.00 52.68 ? 71 LYS A CE 1 ATOM 500 N NZ . LYS A 1 63 ? 137.540 68.082 -45.481 1.00 53.43 ? 71 LYS A NZ 1 ATOM 501 N N . GLY A 1 64 ? 142.072 66.546 -44.289 1.00 33.23 ? 72 GLY A N 1 ATOM 502 C CA . GLY A 1 64 ? 142.984 66.198 -45.366 1.00 32.17 ? 72 GLY A CA 1 ATOM 503 C C . GLY A 1 64 ? 142.573 66.754 -46.723 1.00 31.69 ? 72 GLY A C 1 ATOM 504 O O . GLY A 1 64 ? 141.830 67.735 -46.797 1.00 30.66 ? 72 GLY A O 1 ATOM 505 N N . LYS A 1 65 ? 143.055 66.132 -47.800 1.00 30.73 ? 73 LYS A N 1 ATOM 506 C CA . LYS A 1 65 ? 142.729 66.581 -49.150 1.00 30.45 ? 73 LYS A CA 1 ATOM 507 C C . LYS A 1 65 ? 142.022 65.506 -49.972 1.00 28.98 ? 73 LYS A C 1 ATOM 508 O O . LYS A 1 65 ? 142.128 64.316 -49.687 1.00 28.46 ? 73 LYS A O 1 ATOM 509 C CB . LYS A 1 65 ? 143.995 67.054 -49.873 1.00 31.15 ? 73 LYS A CB 1 ATOM 510 C CG . LYS A 1 65 ? 144.758 68.117 -49.096 1.00 35.26 ? 73 LYS A CG 1 ATOM 511 C CD . LYS A 1 65 ? 145.439 69.127 -50.008 1.00 39.40 ? 73 LYS A CD 1 ATOM 512 C CE . LYS A 1 65 ? 146.590 68.525 -50.800 1.00 42.24 ? 73 LYS A CE 1 ATOM 513 N NZ . LYS A 1 65 ? 147.170 69.534 -51.743 1.00 44.37 ? 73 LYS A NZ 1 ATOM 514 N N . MET A 1 66 ? 141.291 65.941 -50.992 1.00 28.24 ? 74 MET A N 1 ATOM 515 C CA . MET A 1 66 ? 140.544 65.039 -51.864 1.00 27.88 ? 74 MET A CA 1 ATOM 516 C C . MET A 1 66 ? 141.017 65.210 -53.302 1.00 28.76 ? 74 MET A C 1 ATOM 517 O O . MET A 1 66 ? 141.282 66.325 -53.752 1.00 28.85 ? 74 MET A O 1 ATOM 518 C CB . MET A 1 66 ? 139.049 65.360 -51.766 1.00 29.54 ? 74 MET A CB 1 ATOM 519 C CG . MET A 1 66 ? 138.114 64.408 -52.501 1.00 31.23 ? 74 MET A CG 1 ATOM 520 S SD . MET A 1 66 ? 137.907 64.745 -54.272 1.00 37.89 ? 74 MET A SD 1 ATOM 521 C CE . MET A 1 66 ? 136.700 66.078 -54.258 1.00 34.11 ? 74 MET A CE 1 ATOM 522 N N . SER A 1 67 ? 141.137 64.102 -54.022 1.00 28.60 ? 75 SER A N 1 ATOM 523 C CA . SER A 1 67 ? 141.558 64.163 -55.411 1.00 27.06 ? 75 SER A CA 1 ATOM 524 C C . SER A 1 67 ? 140.909 63.051 -56.224 1.00 26.04 ? 75 SER A C 1 ATOM 525 O O . SER A 1 67 ? 140.464 62.044 -55.678 1.00 26.42 ? 75 SER A O 1 ATOM 526 C CB . SER A 1 67 ? 143.081 64.063 -55.508 1.00 28.01 ? 75 SER A CB 1 ATOM 527 O OG . SER A 1 67 ? 143.556 62.838 -54.976 1.00 33.26 ? 75 SER A OG 1 ATOM 528 N N . THR A 1 68 ? 140.841 63.247 -57.533 1.00 25.80 ? 76 THR A N 1 ATOM 529 C CA . THR A 1 68 ? 140.267 62.249 -58.428 1.00 25.42 ? 76 THR A CA 1 ATOM 530 C C . THR A 1 68 ? 141.202 62.122 -59.620 1.00 24.56 ? 76 THR A C 1 ATOM 531 O O . THR A 1 68 ? 142.175 62.867 -59.737 1.00 24.28 ? 76 THR A O 1 ATOM 532 C CB . THR A 1 68 ? 138.873 62.672 -58.960 1.00 25.49 ? 76 THR A CB 1 ATOM 533 O OG1 . THR A 1 68 ? 139.000 63.870 -59.734 1.00 25.14 ? 76 THR A OG1 1 ATOM 534 C CG2 . THR A 1 68 ? 137.908 62.922 -57.819 1.00 25.30 ? 76 THR A CG2 1 ATOM 535 N N . TYR A 1 69 ? 140.919 61.169 -60.497 1.00 23.46 ? 77 TYR A N 1 ATOM 536 C CA . TYR A 1 69 ? 141.733 60.997 -61.687 1.00 24.06 ? 77 TYR A CA 1 ATOM 537 C C . TYR A 1 69 ? 141.031 60.120 -62.714 1.00 24.02 ? 77 TYR A C 1 ATOM 538 O O . TYR A 1 69 ? 140.053 59.430 -62.405 1.00 23.63 ? 77 TYR A O 1 ATOM 539 C CB . TYR A 1 69 ? 143.093 60.391 -61.340 1.00 23.35 ? 77 TYR A CB 1 ATOM 540 C CG . TYR A 1 69 ? 143.066 58.900 -61.106 1.00 23.58 ? 77 TYR A CG 1 ATOM 541 C CD1 . TYR A 1 69 ? 142.714 58.379 -59.866 1.00 22.81 ? 77 TYR A CD1 1 ATOM 542 C CD2 . TYR A 1 69 ? 143.382 58.006 -62.134 1.00 22.67 ? 77 TYR A CD2 1 ATOM 543 C CE1 . TYR A 1 69 ? 142.675 56.999 -59.644 1.00 24.39 ? 77 TYR A CE1 1 ATOM 544 C CE2 . TYR A 1 69 ? 143.344 56.623 -61.927 1.00 24.05 ? 77 TYR A CE2 1 ATOM 545 C CZ . TYR A 1 69 ? 142.987 56.125 -60.676 1.00 25.32 ? 77 TYR A CZ 1 ATOM 546 O OH . TYR A 1 69 ? 142.920 54.762 -60.456 1.00 23.79 ? 77 TYR A OH 1 ATOM 547 N N . ARG A 1 70 ? 141.528 60.170 -63.943 1.00 23.57 ? 78 ARG A N 1 ATOM 548 C CA . ARG A 1 70 ? 140.975 59.378 -65.033 1.00 24.61 ? 78 ARG A CA 1 ATOM 549 C C . ARG A 1 70 ? 142.116 58.572 -65.626 1.00 24.33 ? 78 ARG A C 1 ATOM 550 O O . ARG A 1 70 ? 143.269 58.994 -65.568 1.00 24.80 ? 78 ARG A O 1 ATOM 551 C CB . ARG A 1 70 ? 140.389 60.283 -66.126 1.00 24.62 ? 78 ARG A CB 1 ATOM 552 C CG . ARG A 1 70 ? 139.030 60.910 -65.835 1.00 27.12 ? 78 ARG A CG 1 ATOM 553 C CD . ARG A 1 70 ? 138.545 61.632 -67.080 1.00 30.26 ? 78 ARG A CD 1 ATOM 554 N NE . ARG A 1 70 ? 137.091 61.625 -67.234 1.00 34.14 ? 78 ARG A NE 1 ATOM 555 C CZ . ARG A 1 70 ? 136.284 62.592 -66.808 1.00 35.94 ? 78 ARG A CZ 1 ATOM 556 N NH1 . ARG A 1 70 ? 136.782 63.663 -66.189 1.00 37.43 ? 78 ARG A NH1 1 ATOM 557 N NH2 . ARG A 1 70 ? 134.977 62.498 -67.021 1.00 34.60 ? 78 ARG A NH2 1 ATOM 558 N N . PHE A 1 71 ? 141.819 57.404 -66.174 1.00 25.68 ? 79 PHE A N 1 ATOM 559 C CA . PHE A 1 71 ? 142.882 56.645 -66.786 1.00 28.14 ? 79 PHE A CA 1 ATOM 560 C C . PHE A 1 71 ? 142.579 56.584 -68.273 1.00 30.65 ? 79 PHE A C 1 ATOM 561 O O . PHE A 1 71 ? 143.115 57.374 -69.053 1.00 35.66 ? 79 PHE A O 1 ATOM 562 C CB . PHE A 1 71 ? 143.010 55.248 -66.191 1.00 27.18 ? 79 PHE A CB 1 ATOM 563 C CG . PHE A 1 71 ? 144.329 54.601 -66.504 1.00 26.05 ? 79 PHE A CG 1 ATOM 564 C CD1 . PHE A 1 71 ? 145.512 55.130 -65.993 1.00 25.20 ? 79 PHE A CD1 1 ATOM 565 C CD2 . PHE A 1 71 ? 144.400 53.513 -67.373 1.00 24.98 ? 79 PHE A CD2 1 ATOM 566 C CE1 . PHE A 1 71 ? 146.747 54.588 -66.348 1.00 25.28 ? 79 PHE A CE1 1 ATOM 567 C CE2 . PHE A 1 71 ? 145.629 52.963 -67.735 1.00 24.69 ? 79 PHE A CE2 1 ATOM 568 C CZ . PHE A 1 71 ? 146.803 53.499 -67.225 1.00 24.32 ? 79 PHE A CZ 1 ATOM 569 N N . PHE A 1 72 ? 141.731 55.666 -68.700 1.00 30.05 ? 80 PHE A N 1 ATOM 570 C CA . PHE A 1 72 ? 141.418 55.644 -70.123 1.00 29.09 ? 80 PHE A CA 1 ATOM 571 C C . PHE A 1 72 ? 139.987 56.141 -70.132 1.00 29.70 ? 80 PHE A C 1 ATOM 572 O O . PHE A 1 72 ? 139.746 57.347 -70.051 1.00 27.96 ? 80 PHE A O 1 ATOM 573 C CB . PHE A 1 72 ? 141.536 54.223 -70.673 1.00 28.52 ? 80 PHE A CB 1 ATOM 574 C CG . PHE A 1 72 ? 141.226 54.114 -72.130 1.00 26.86 ? 80 PHE A CG 1 ATOM 575 C CD1 . PHE A 1 72 ? 141.840 54.956 -73.054 1.00 26.30 ? 80 PHE A CD1 1 ATOM 576 C CD2 . PHE A 1 72 ? 140.312 53.170 -72.583 1.00 27.29 ? 80 PHE A CD2 1 ATOM 577 C CE1 . PHE A 1 72 ? 141.537 54.866 -74.404 1.00 24.51 ? 80 PHE A CE1 1 ATOM 578 C CE2 . PHE A 1 72 ? 140.003 53.072 -73.934 1.00 25.68 ? 80 PHE A CE2 1 ATOM 579 C CZ . PHE A 1 72 ? 140.620 53.923 -74.846 1.00 25.08 ? 80 PHE A CZ 1 ATOM 580 N N . ASN A 1 73 ? 139.038 55.215 -70.213 1.00 29.48 ? 81 ASN A N 1 ATOM 581 C CA . ASN A 1 73 ? 137.634 55.587 -70.145 1.00 28.16 ? 81 ASN A CA 1 ATOM 582 C C . ASN A 1 73 ? 137.213 55.336 -68.701 1.00 27.38 ? 81 ASN A C 1 ATOM 583 O O . ASN A 1 73 ? 136.032 55.214 -68.401 1.00 28.93 ? 81 ASN A O 1 ATOM 584 C CB . ASN A 1 73 ? 136.784 54.744 -71.098 1.00 28.13 ? 81 ASN A CB 1 ATOM 585 C CG . ASN A 1 73 ? 137.192 53.294 -71.111 1.00 28.59 ? 81 ASN A CG 1 ATOM 586 O OD1 . ASN A 1 73 ? 137.769 52.788 -70.149 1.00 29.81 ? 81 ASN A OD1 1 ATOM 587 N ND2 . ASN A 1 73 ? 136.886 52.608 -72.205 1.00 29.97 ? 81 ASN A ND2 1 ATOM 588 N N . TYR A 1 74 ? 138.194 55.252 -67.808 1.00 26.17 ? 82 TYR A N 1 ATOM 589 C CA . TYR A 1 74 ? 137.907 55.015 -66.399 1.00 25.56 ? 82 TYR A CA 1 ATOM 590 C C . TYR A 1 74 ? 137.915 56.322 -65.611 1.00 26.12 ? 82 TYR A C 1 ATOM 591 O O . TYR A 1 74 ? 138.787 57.166 -65.812 1.00 26.51 ? 82 TYR A O 1 ATOM 592 C CB . TYR A 1 74 ? 138.948 54.066 -65.793 1.00 24.82 ? 82 TYR A CB 1 ATOM 593 C CG . TYR A 1 74 ? 138.874 53.952 -64.279 1.00 22.30 ? 82 TYR A CG 1 ATOM 594 C CD1 . TYR A 1 74 ? 138.011 53.041 -63.665 1.00 21.17 ? 82 TYR A CD1 1 ATOM 595 C CD2 . TYR A 1 74 ? 139.673 54.757 -63.461 1.00 21.34 ? 82 TYR A CD2 1 ATOM 596 C CE1 . TYR A 1 74 ? 137.947 52.931 -62.273 1.00 20.69 ? 82 TYR A CE1 1 ATOM 597 C CE2 . TYR A 1 74 ? 139.617 54.656 -62.066 1.00 21.01 ? 82 TYR A CE2 1 ATOM 598 C CZ . TYR A 1 74 ? 138.755 53.739 -61.481 1.00 21.39 ? 82 TYR A CZ 1 ATOM 599 O OH . TYR A 1 74 ? 138.708 53.619 -60.108 1.00 19.40 ? 82 TYR A OH 1 ATOM 600 N N . SER A 1 75 ? 136.940 56.484 -64.722 1.00 26.21 ? 83 SER A N 1 ATOM 601 C CA . SER A 1 75 ? 136.845 57.676 -63.883 1.00 26.79 ? 83 SER A CA 1 ATOM 602 C C . SER A 1 75 ? 136.860 57.202 -62.446 1.00 25.88 ? 83 SER A C 1 ATOM 603 O O . SER A 1 75 ? 135.980 56.455 -62.026 1.00 27.27 ? 83 SER A O 1 ATOM 604 C CB . SER A 1 75 ? 135.548 58.447 -64.150 1.00 28.42 ? 83 SER A CB 1 ATOM 605 O OG . SER A 1 75 ? 135.556 59.050 -65.432 1.00 34.32 ? 83 SER A OG 1 ATOM 606 N N . SER A 1 76 ? 137.854 57.644 -61.692 1.00 23.95 ? 84 SER A N 1 ATOM 607 C CA . SER A 1 76 ? 137.987 57.231 -60.310 1.00 22.91 ? 84 SER A CA 1 ATOM 608 C C . SER A 1 76 ? 136.900 57.817 -59.445 1.00 23.67 ? 84 SER A C 1 ATOM 609 O O . SER A 1 76 ? 136.115 58.655 -59.880 1.00 22.79 ? 84 SER A O 1 ATOM 610 C CB . SER A 1 76 ? 139.313 57.698 -59.741 1.00 21.58 ? 84 SER A CB 1 ATOM 611 O OG . SER A 1 76 ? 139.230 59.081 -59.448 1.00 20.62 ? 84 SER A OG 1 ATOM 612 N N . GLY A 1 77 ? 136.876 57.359 -58.203 1.00 24.28 ? 85 GLY A N 1 ATOM 613 C CA . GLY A 1 77 ? 135.924 57.870 -57.251 1.00 24.52 ? 85 GLY A CA 1 ATOM 614 C C . GLY A 1 77 ? 136.638 59.037 -56.599 1.00 25.81 ? 85 GLY A C 1 ATOM 615 O O . GLY A 1 77 ? 137.576 59.608 -57.165 1.00 26.73 ? 85 GLY A O 1 ATOM 616 N N . PHE A 1 78 ? 136.213 59.385 -55.397 1.00 24.74 ? 86 PHE A N 1 ATOM 617 C CA . PHE A 1 78 ? 136.808 60.492 -54.680 1.00 23.68 ? 86 PHE A CA 1 ATOM 618 C C . PHE A 1 78 ? 137.793 59.940 -53.669 1.00 23.01 ? 86 PHE A C 1 ATOM 619 O O . PHE A 1 78 ? 137.428 59.239 -52.728 1.00 22.11 ? 86 PHE A O 1 ATOM 620 C CB . PHE A 1 78 ? 135.684 61.295 -54.039 1.00 24.03 ? 86 PHE A CB 1 ATOM 621 C CG . PHE A 1 78 ? 134.645 61.725 -55.033 1.00 25.34 ? 86 PHE A CG 1 ATOM 622 C CD1 . PHE A 1 78 ? 134.886 62.794 -55.892 1.00 26.05 ? 86 PHE A CD1 1 ATOM 623 C CD2 . PHE A 1 78 ? 133.460 61.002 -55.181 1.00 26.50 ? 86 PHE A CD2 1 ATOM 624 C CE1 . PHE A 1 78 ? 133.963 63.135 -56.889 1.00 27.31 ? 86 PHE A CE1 1 ATOM 625 C CE2 . PHE A 1 78 ? 132.529 61.334 -56.173 1.00 26.59 ? 86 PHE A CE2 1 ATOM 626 C CZ . PHE A 1 78 ? 132.782 62.401 -57.029 1.00 26.97 ? 86 PHE A CZ 1 ATOM 627 N N . ILE A 1 79 ? 139.061 60.248 -53.901 1.00 23.27 ? 87 ILE A N 1 ATOM 628 C CA . ILE A 1 79 ? 140.134 59.769 -53.053 1.00 22.92 ? 87 ILE A CA 1 ATOM 629 C C . ILE A 1 79 ? 140.511 60.803 -52.014 1.00 22.52 ? 87 ILE A C 1 ATOM 630 O O . ILE A 1 79 ? 140.684 61.987 -52.328 1.00 22.59 ? 87 ILE A O 1 ATOM 631 C CB . ILE A 1 79 ? 141.368 59.409 -53.904 1.00 23.34 ? 87 ILE A CB 1 ATOM 632 C CG1 . ILE A 1 79 ? 140.959 58.433 -55.011 1.00 21.74 ? 87 ILE A CG1 1 ATOM 633 C CG2 . ILE A 1 79 ? 142.435 58.777 -53.029 1.00 22.99 ? 87 ILE A CG2 1 ATOM 634 C CD1 . ILE A 1 79 ? 141.994 58.284 -56.101 1.00 22.91 ? 87 ILE A CD1 1 ATOM 635 N N . HIS A 1 80 ? 140.629 60.341 -50.774 1.00 21.48 ? 88 HIS A N 1 ATOM 636 C CA . HIS A 1 80 ? 140.974 61.205 -49.660 1.00 20.46 ? 88 HIS A CA 1 ATOM 637 C C . HIS A 1 80 ? 142.283 60.777 -48.995 1.00 20.89 ? 88 HIS A C 1 ATOM 638 O O . HIS A 1 80 ? 142.563 59.584 -48.858 1.00 22.52 ? 88 HIS A O 1 ATOM 639 C CB . HIS A 1 80 ? 139.864 61.177 -48.612 1.00 19.56 ? 88 HIS A CB 1 ATOM 640 C CG . HIS A 1 80 ? 138.511 61.539 -49.140 1.00 20.00 ? 88 HIS A CG 1 ATOM 641 N ND1 . HIS A 1 80 ? 137.695 60.632 -49.783 1.00 20.36 ? 88 HIS A ND1 1 ATOM 642 C CD2 . HIS A 1 80 ? 137.823 62.705 -49.102 1.00 18.39 ? 88 HIS A CD2 1 ATOM 643 C CE1 . HIS A 1 80 ? 136.559 61.223 -50.114 1.00 19.26 ? 88 HIS A CE1 1 ATOM 644 N NE2 . HIS A 1 80 ? 136.612 62.481 -49.712 1.00 20.23 ? 88 HIS A NE2 1 ATOM 645 N N . HIS A 1 81 ? 143.077 61.758 -48.579 1.00 19.17 ? 89 HIS A N 1 ATOM 646 C CA . HIS A 1 81 ? 144.340 61.508 -47.898 1.00 18.83 ? 89 HIS A CA 1 ATOM 647 C C . HIS A 1 81 ? 144.418 62.532 -46.770 1.00 20.01 ? 89 HIS A C 1 ATOM 648 O O . HIS A 1 81 ? 144.348 63.741 -47.010 1.00 18.01 ? 89 HIS A O 1 ATOM 649 C CB . HIS A 1 81 ? 145.527 61.693 -48.854 1.00 18.18 ? 89 HIS A CB 1 ATOM 650 C CG . HIS A 1 81 ? 145.653 60.620 -49.895 1.00 18.96 ? 89 HIS A CG 1 ATOM 651 N ND1 . HIS A 1 81 ? 146.062 59.336 -49.600 1.00 19.80 ? 89 HIS A ND1 1 ATOM 652 C CD2 . HIS A 1 81 ? 145.449 60.651 -51.234 1.00 18.45 ? 89 HIS A CD2 1 ATOM 653 C CE1 . HIS A 1 81 ? 146.106 58.623 -50.713 1.00 19.34 ? 89 HIS A CE1 1 ATOM 654 N NE2 . HIS A 1 81 ? 145.739 59.397 -51.719 1.00 19.32 ? 89 HIS A NE2 1 ATOM 655 N N . THR A 1 82 ? 144.540 62.042 -45.541 1.00 21.34 ? 90 THR A N 1 ATOM 656 C CA . THR A 1 82 ? 144.624 62.908 -44.373 1.00 23.35 ? 90 THR A CA 1 ATOM 657 C C . THR A 1 82 ? 145.764 62.438 -43.495 1.00 24.89 ? 90 THR A C 1 ATOM 658 O O . THR A 1 82 ? 145.910 61.243 -43.245 1.00 25.78 ? 90 THR A O 1 ATOM 659 C CB . THR A 1 82 ? 143.331 62.859 -43.523 1.00 24.13 ? 90 THR A CB 1 ATOM 660 O OG1 . THR A 1 82 ? 142.217 63.265 -44.321 1.00 25.66 ? 90 THR A OG1 1 ATOM 661 C CG2 . THR A 1 82 ? 143.442 63.786 -42.320 1.00 22.71 ? 90 THR A CG2 1 ATOM 662 N N . THR A 1 83 ? 146.560 63.383 -43.017 1.00 26.43 ? 91 THR A N 1 ATOM 663 C CA . THR A 1 83 ? 147.687 63.061 -42.163 1.00 27.44 ? 91 THR A CA 1 ATOM 664 C C . THR A 1 83 ? 147.441 63.485 -40.721 1.00 28.82 ? 91 THR A C 1 ATOM 665 O O . THR A 1 83 ? 147.253 64.669 -40.436 1.00 28.57 ? 91 THR A O 1 ATOM 666 C CB . THR A 1 83 ? 148.967 63.742 -42.677 1.00 27.16 ? 91 THR A CB 1 ATOM 667 O OG1 . THR A 1 83 ? 149.276 63.235 -43.979 1.00 29.19 ? 91 THR A OG1 1 ATOM 668 C CG2 . THR A 1 83 ? 150.134 63.467 -41.755 1.00 26.17 ? 91 THR A CG2 1 ATOM 669 N N . ILE A 1 84 ? 147.430 62.499 -39.827 1.00 30.67 ? 92 ILE A N 1 ATOM 670 C CA . ILE A 1 84 ? 147.244 62.720 -38.395 1.00 32.78 ? 92 ILE A CA 1 ATOM 671 C C . ILE A 1 84 ? 148.647 62.767 -37.801 1.00 34.03 ? 92 ILE A C 1 ATOM 672 O O . ILE A 1 84 ? 149.453 61.872 -38.054 1.00 34.50 ? 92 ILE A O 1 ATOM 673 C CB . ILE A 1 84 ? 146.501 61.547 -37.727 1.00 32.71 ? 92 ILE A CB 1 ATOM 674 C CG1 . ILE A 1 84 ? 145.117 61.365 -38.347 1.00 32.90 ? 92 ILE A CG1 1 ATOM 675 C CG2 . ILE A 1 84 ? 146.372 61.803 -36.240 1.00 33.89 ? 92 ILE A CG2 1 ATOM 676 C CD1 . ILE A 1 84 ? 144.352 60.171 -37.770 1.00 32.44 ? 92 ILE A CD1 1 ATOM 677 N N . ARG A 1 85 ? 148.941 63.793 -37.010 1.00 36.30 ? 93 ARG A N 1 ATOM 678 C CA . ARG A 1 85 ? 150.268 63.918 -36.421 1.00 39.07 ? 93 ARG A CA 1 ATOM 679 C C . ARG A 1 85 ? 150.278 64.206 -34.917 1.00 38.69 ? 93 ARG A C 1 ATOM 680 O O . ARG A 1 85 ? 149.228 64.413 -34.305 1.00 38.18 ? 93 ARG A O 1 ATOM 681 C CB . ARG A 1 85 ? 151.049 64.999 -37.171 1.00 41.02 ? 93 ARG A CB 1 ATOM 682 C CG . ARG A 1 85 ? 150.222 66.219 -37.495 1.00 47.37 ? 93 ARG A CG 1 ATOM 683 C CD . ARG A 1 85 ? 150.993 67.231 -38.342 1.00 54.46 ? 93 ARG A CD 1 ATOM 684 N NE . ARG A 1 85 ? 151.446 66.680 -39.621 1.00 59.55 ? 93 ARG A NE 1 ATOM 685 C CZ . ARG A 1 85 ? 152.677 66.220 -39.851 1.00 62.68 ? 93 ARG A CZ 1 ATOM 686 N NH1 . ARG A 1 85 ? 153.595 66.246 -38.886 1.00 63.31 ? 93 ARG A NH1 1 ATOM 687 N NH2 . ARG A 1 85 ? 152.996 65.732 -41.047 1.00 62.75 ? 93 ARG A NH2 1 ATOM 688 N N . LYS A 1 86 ? 151.479 64.206 -34.337 1.00 38.39 ? 94 LYS A N 1 ATOM 689 C CA . LYS A 1 86 ? 151.671 64.463 -32.912 1.00 37.81 ? 94 LYS A CA 1 ATOM 690 C C . LYS A 1 86 ? 151.070 63.365 -32.037 1.00 36.69 ? 94 LYS A C 1 ATOM 691 O O . LYS A 1 86 ? 150.743 63.602 -30.874 1.00 37.06 ? 94 LYS A O 1 ATOM 692 C CB . LYS A 1 86 ? 151.060 65.814 -32.522 1.00 39.75 ? 94 LYS A CB 1 ATOM 693 C CG . LYS A 1 86 ? 151.707 67.027 -33.173 1.00 42.99 ? 94 LYS A CG 1 ATOM 694 C CD . LYS A 1 86 ? 150.900 68.294 -32.888 1.00 47.75 ? 94 LYS A CD 1 ATOM 695 C CE . LYS A 1 86 ? 151.481 69.510 -33.609 1.00 51.33 ? 94 LYS A CE 1 ATOM 696 N NZ . LYS A 1 86 ? 152.883 69.820 -33.174 1.00 53.91 ? 94 LYS A NZ 1 ATOM 697 N N . LEU A 1 87 ? 150.925 62.166 -32.592 1.00 34.92 ? 95 LEU A N 1 ATOM 698 C CA . LEU A 1 87 ? 150.374 61.052 -31.833 1.00 33.22 ? 95 LEU A CA 1 ATOM 699 C C . LEU A 1 87 ? 151.314 60.647 -30.702 1.00 33.05 ? 95 LEU A C 1 ATOM 700 O O . LEU A 1 87 ? 152.473 61.066 -30.665 1.00 32.15 ? 95 LEU A O 1 ATOM 701 C CB . LEU A 1 87 ? 150.130 59.855 -32.749 1.00 31.77 ? 95 LEU A CB 1 ATOM 702 C CG . LEU A 1 87 ? 149.130 60.078 -33.888 1.00 32.36 ? 95 LEU A CG 1 ATOM 703 C CD1 . LEU A 1 87 ? 149.019 58.815 -34.726 1.00 31.13 ? 95 LEU A CD1 1 ATOM 704 C CD2 . LEU A 1 87 ? 147.768 60.462 -33.316 1.00 32.22 ? 95 LEU A CD2 1 ATOM 705 N N . LYS A 1 88 ? 150.814 59.845 -29.771 1.00 33.21 ? 96 LYS A N 1 ATOM 706 C CA . LYS A 1 88 ? 151.639 59.392 -28.661 1.00 35.54 ? 96 LYS A CA 1 ATOM 707 C C . LYS A 1 88 ? 152.154 58.006 -28.989 1.00 34.47 ? 96 LYS A C 1 ATOM 708 O O . LYS A 1 88 ? 151.459 57.210 -29.620 1.00 34.39 ? 96 LYS A O 1 ATOM 709 C CB . LYS A 1 88 ? 150.830 59.370 -27.357 1.00 38.60 ? 96 LYS A CB 1 ATOM 710 C CG . LYS A 1 88 ? 150.506 60.764 -26.818 1.00 44.69 ? 96 LYS A CG 1 ATOM 711 C CD . LYS A 1 88 ? 149.590 60.731 -25.590 1.00 49.97 ? 96 LYS A CD 1 ATOM 712 C CE . LYS A 1 88 ? 150.253 60.044 -24.392 1.00 53.72 ? 96 LYS A CE 1 ATOM 713 N NZ . LYS A 1 88 ? 149.451 60.156 -23.126 1.00 54.67 ? 96 LYS A NZ 1 ATOM 714 N N . TYR A 1 89 ? 153.381 57.727 -28.570 1.00 33.73 ? 97 TYR A N 1 ATOM 715 C CA . TYR A 1 89 ? 153.998 56.435 -28.827 1.00 33.45 ? 97 TYR A CA 1 ATOM 716 C C . TYR A 1 89 ? 153.303 55.283 -28.124 1.00 33.72 ? 97 TYR A C 1 ATOM 717 O O . TYR A 1 89 ? 152.704 55.437 -27.064 1.00 33.30 ? 97 TYR A O 1 ATOM 718 C CB . TYR A 1 89 ? 155.465 56.461 -28.409 1.00 32.79 ? 97 TYR A CB 1 ATOM 719 C CG . TYR A 1 89 ? 156.364 57.202 -29.363 1.00 33.32 ? 97 TYR A CG 1 ATOM 720 C CD1 . TYR A 1 89 ? 156.629 56.689 -30.634 1.00 33.86 ? 97 TYR A CD1 1 ATOM 721 C CD2 . TYR A 1 89 ? 156.979 58.402 -28.990 1.00 33.33 ? 97 TYR A CD2 1 ATOM 722 C CE1 . TYR A 1 89 ? 157.491 57.345 -31.511 1.00 34.77 ? 97 TYR A CE1 1 ATOM 723 C CE2 . TYR A 1 89 ? 157.841 59.069 -29.858 1.00 35.21 ? 97 TYR A CE2 1 ATOM 724 C CZ . TYR A 1 89 ? 158.095 58.532 -31.116 1.00 36.47 ? 97 TYR A CZ 1 ATOM 725 O OH . TYR A 1 89 ? 158.973 59.164 -31.968 1.00 38.03 ? 97 TYR A OH 1 ATOM 726 N N . ASN A 1 90 ? 153.400 54.120 -28.744 1.00 35.32 ? 98 ASN A N 1 ATOM 727 C CA . ASN A 1 90 ? 152.826 52.891 -28.224 1.00 36.75 ? 98 ASN A CA 1 ATOM 728 C C . ASN A 1 90 ? 151.450 53.003 -27.560 1.00 35.98 ? 98 ASN A C 1 ATOM 729 O O . ASN A 1 90 ? 151.251 52.520 -26.442 1.00 35.84 ? 98 ASN A O 1 ATOM 730 C CB . ASN A 1 90 ? 153.818 52.238 -27.257 1.00 38.66 ? 98 ASN A CB 1 ATOM 731 C CG . ASN A 1 90 ? 153.500 50.780 -27.002 1.00 42.03 ? 98 ASN A CG 1 ATOM 732 O OD1 . ASN A 1 90 ? 153.352 49.995 -27.943 1.00 45.14 ? 98 ASN A OD1 1 ATOM 733 N ND2 . ASN A 1 90 ? 153.393 50.405 -25.733 1.00 43.46 ? 98 ASN A ND2 1 ATOM 734 N N . THR A 1 91 ? 150.501 53.632 -28.247 1.00 35.34 ? 99 THR A N 1 ATOM 735 C CA . THR A 1 91 ? 149.144 53.751 -27.720 1.00 34.98 ? 99 THR A CA 1 ATOM 736 C C . THR A 1 91 ? 148.131 53.398 -28.817 1.00 35.01 ? 99 THR A C 1 ATOM 737 O O . THR A 1 91 ? 148.372 53.646 -30.006 1.00 35.05 ? 99 THR A O 1 ATOM 738 C CB . THR A 1 91 ? 148.853 55.182 -27.168 1.00 34.52 ? 99 THR A CB 1 ATOM 739 O OG1 . THR A 1 91 ? 147.932 55.858 -28.029 1.00 35.79 ? 99 THR A OG1 1 ATOM 740 C CG2 . THR A 1 91 ? 150.131 55.996 -27.066 1.00 33.16 ? 99 THR A CG2 1 ATOM 741 N N . LYS A 1 92 ? 147.012 52.799 -28.417 1.00 34.26 ? 100 LYS A N 1 ATOM 742 C CA . LYS A 1 92 ? 145.966 52.415 -29.358 1.00 33.03 ? 100 LYS A CA 1 ATOM 743 C C . LYS A 1 92 ? 145.067 53.616 -29.650 1.00 32.41 ? 100 LYS A C 1 ATOM 744 O O . LYS A 1 92 ? 144.593 54.290 -28.734 1.00 33.00 ? 100 LYS A O 1 ATOM 745 C CB . LYS A 1 92 ? 145.128 51.275 -28.773 1.00 33.29 ? 100 LYS A CB 1 ATOM 746 C CG . LYS A 1 92 ? 144.161 50.635 -29.758 1.00 34.75 ? 100 LYS A CG 1 ATOM 747 C CD . LYS A 1 92 ? 143.330 49.569 -29.070 1.00 37.42 ? 100 LYS A CD 1 ATOM 748 C CE . LYS A 1 92 ? 142.412 48.852 -30.042 1.00 39.10 ? 100 LYS A CE 1 ATOM 749 N NZ . LYS A 1 92 ? 141.563 47.850 -29.330 1.00 41.83 ? 100 LYS A NZ 1 ATOM 750 N N . TYR A 1 93 ? 144.846 53.880 -30.932 1.00 31.45 ? 101 TYR A N 1 ATOM 751 C CA . TYR A 1 93 ? 144.007 54.990 -31.374 1.00 29.67 ? 101 TYR A CA 1 ATOM 752 C C . TYR A 1 93 ? 142.814 54.505 -32.181 1.00 29.94 ? 101 TYR A C 1 ATOM 753 O O . TYR A 1 93 ? 142.894 53.504 -32.891 1.00 30.84 ? 101 TYR A O 1 ATOM 754 C CB . TYR A 1 93 ? 144.813 55.933 -32.259 1.00 28.34 ? 101 TYR A CB 1 ATOM 755 C CG . TYR A 1 93 ? 145.623 56.972 -31.521 1.00 28.54 ? 101 TYR A CG 1 ATOM 756 C CD1 . TYR A 1 93 ? 145.053 58.187 -31.157 1.00 28.03 ? 101 TYR A CD1 1 ATOM 757 C CD2 . TYR A 1 93 ? 146.965 56.750 -31.205 1.00 28.80 ? 101 TYR A CD2 1 ATOM 758 C CE1 . TYR A 1 93 ? 145.789 59.156 -30.503 1.00 29.10 ? 101 TYR A CE1 1 ATOM 759 C CE2 . TYR A 1 93 ? 147.717 57.717 -30.545 1.00 29.46 ? 101 TYR A CE2 1 ATOM 760 C CZ . TYR A 1 93 ? 147.121 58.918 -30.196 1.00 30.78 ? 101 TYR A CZ 1 ATOM 761 O OH . TYR A 1 93 ? 147.854 59.880 -29.526 1.00 33.35 ? 101 TYR A OH 1 ATOM 762 N N . TYR A 1 94 ? 141.704 55.220 -32.064 1.00 30.21 ? 102 TYR A N 1 ATOM 763 C CA . TYR A 1 94 ? 140.506 54.904 -32.832 1.00 29.37 ? 102 TYR A CA 1 ATOM 764 C C . TYR A 1 94 ? 140.352 56.041 -33.826 1.00 28.69 ? 102 TYR A C 1 ATOM 765 O O . TYR A 1 94 ? 140.754 57.176 -33.542 1.00 27.06 ? 102 TYR A O 1 ATOM 766 C CB . TYR A 1 94 ? 139.276 54.861 -31.936 1.00 31.45 ? 102 TYR A CB 1 ATOM 767 C CG . TYR A 1 94 ? 139.191 53.620 -31.100 1.00 35.37 ? 102 TYR A CG 1 ATOM 768 C CD1 . TYR A 1 94 ? 138.784 52.414 -31.663 1.00 36.62 ? 102 TYR A CD1 1 ATOM 769 C CD2 . TYR A 1 94 ? 139.554 53.635 -29.751 1.00 36.24 ? 102 TYR A CD2 1 ATOM 770 C CE1 . TYR A 1 94 ? 138.743 51.243 -30.909 1.00 38.94 ? 102 TYR A CE1 1 ATOM 771 C CE2 . TYR A 1 94 ? 139.520 52.472 -28.986 1.00 38.70 ? 102 TYR A CE2 1 ATOM 772 C CZ . TYR A 1 94 ? 139.114 51.279 -29.572 1.00 39.77 ? 102 TYR A CZ 1 ATOM 773 O OH . TYR A 1 94 ? 139.091 50.120 -28.827 1.00 43.43 ? 102 TYR A OH 1 ATOM 774 N N . TYR A 1 95 ? 139.802 55.746 -34.998 1.00 28.14 ? 103 TYR A N 1 ATOM 775 C CA . TYR A 1 95 ? 139.590 56.793 -35.984 1.00 28.20 ? 103 TYR A CA 1 ATOM 776 C C . TYR A 1 95 ? 138.371 56.484 -36.831 1.00 29.79 ? 103 TYR A C 1 ATOM 777 O O . TYR A 1 95 ? 138.113 55.326 -37.178 1.00 29.64 ? 103 TYR A O 1 ATOM 778 C CB . TYR A 1 95 ? 140.849 57.006 -36.851 1.00 27.45 ? 103 TYR A CB 1 ATOM 779 C CG . TYR A 1 95 ? 141.134 55.966 -37.918 1.00 25.90 ? 103 TYR A CG 1 ATOM 780 C CD1 . TYR A 1 95 ? 140.555 56.059 -39.181 1.00 25.07 ? 103 TYR A CD1 1 ATOM 781 C CD2 . TYR A 1 95 ? 141.997 54.895 -37.667 1.00 25.32 ? 103 TYR A CD2 1 ATOM 782 C CE1 . TYR A 1 95 ? 140.826 55.114 -40.173 1.00 25.44 ? 103 TYR A CE1 1 ATOM 783 C CE2 . TYR A 1 95 ? 142.274 53.941 -38.648 1.00 24.57 ? 103 TYR A CE2 1 ATOM 784 C CZ . TYR A 1 95 ? 141.684 54.056 -39.900 1.00 25.26 ? 103 TYR A CZ 1 ATOM 785 O OH . TYR A 1 95 ? 141.930 53.105 -40.873 1.00 23.75 ? 103 TYR A OH 1 ATOM 786 N N . GLU A 1 96 ? 137.599 57.526 -37.122 1.00 31.27 ? 104 GLU A N 1 ATOM 787 C CA . GLU A 1 96 ? 136.400 57.385 -37.928 1.00 33.11 ? 104 GLU A CA 1 ATOM 788 C C . GLU A 1 96 ? 136.541 58.182 -39.207 1.00 33.55 ? 104 GLU A C 1 ATOM 789 O O . GLU A 1 96 ? 137.139 59.263 -39.230 1.00 33.43 ? 104 GLU A O 1 ATOM 790 C CB . GLU A 1 96 ? 135.165 57.854 -37.159 1.00 35.53 ? 104 GLU A CB 1 ATOM 791 C CG . GLU A 1 96 ? 134.684 56.891 -36.090 1.00 38.64 ? 104 GLU A CG 1 ATOM 792 C CD . GLU A 1 96 ? 133.533 57.463 -35.295 1.00 40.73 ? 104 GLU A CD 1 ATOM 793 O OE1 . GLU A 1 96 ? 133.718 58.549 -34.699 1.00 41.85 ? 104 GLU A OE1 1 ATOM 794 O OE2 . GLU A 1 96 ? 132.453 56.832 -35.271 1.00 42.16 ? 104 GLU A OE2 1 ATOM 795 N N . VAL A 1 97 ? 135.962 57.628 -40.265 1.00 33.98 ? 105 VAL A N 1 ATOM 796 C CA . VAL A 1 97 ? 136.007 58.207 -41.589 1.00 33.23 ? 105 VAL A CA 1 ATOM 797 C C . VAL A 1 97 ? 134.603 58.256 -42.199 1.00 33.54 ? 105 VAL A C 1 ATOM 798 O O . VAL A 1 97 ? 133.779 57.384 -41.934 1.00 32.76 ? 105 VAL A O 1 ATOM 799 C CB . VAL A 1 97 ? 136.942 57.357 -42.469 1.00 33.55 ? 105 VAL A CB 1 ATOM 800 C CG1 . VAL A 1 97 ? 136.605 57.530 -43.921 1.00 37.07 ? 105 VAL A CG1 1 ATOM 801 C CG2 . VAL A 1 97 ? 138.379 57.760 -42.213 1.00 33.63 ? 105 VAL A CG2 1 ATOM 802 N N . GLY A 1 98 ? 134.343 59.275 -43.019 1.00 33.96 ? 106 GLY A N 1 ATOM 803 C CA . GLY A 1 98 ? 133.047 59.423 -43.658 1.00 32.81 ? 106 GLY A CA 1 ATOM 804 C C . GLY A 1 98 ? 132.075 60.137 -42.745 1.00 33.25 ? 106 GLY A C 1 ATOM 805 O O . GLY A 1 98 ? 130.886 59.839 -42.739 1.00 32.76 ? 106 GLY A O 1 ATOM 806 N N . LEU A 1 99 ? 132.584 61.102 -41.988 1.00 34.15 ? 107 LEU A N 1 ATOM 807 C CA . LEU A 1 99 ? 131.782 61.850 -41.021 1.00 36.74 ? 107 LEU A CA 1 ATOM 808 C C . LEU A 1 99 ? 130.443 62.409 -41.510 1.00 39.10 ? 107 LEU A C 1 ATOM 809 O O . LEU A 1 99 ? 129.404 62.217 -40.868 1.00 42.14 ? 107 LEU A O 1 ATOM 810 C CB . LEU A 1 99 ? 132.621 62.987 -40.433 1.00 34.62 ? 107 LEU A CB 1 ATOM 811 C CG . LEU A 1 99 ? 133.981 62.581 -39.864 1.00 33.27 ? 107 LEU A CG 1 ATOM 812 C CD1 . LEU A 1 99 ? 134.604 63.770 -39.158 1.00 33.52 ? 107 LEU A CD1 1 ATOM 813 C CD2 . LEU A 1 99 ? 133.816 61.422 -38.901 1.00 32.73 ? 107 LEU A CD2 1 ATOM 814 N N . ARG A 1 100 ? 130.462 63.110 -42.631 1.00 39.65 ? 108 ARG A N 1 ATOM 815 C CA . ARG A 1 100 ? 129.236 63.691 -43.158 1.00 40.92 ? 108 ARG A CA 1 ATOM 816 C C . ARG A 1 100 ? 128.085 62.688 -43.361 1.00 40.12 ? 108 ARG A C 1 ATOM 817 O O . ARG A 1 100 ? 126.981 62.885 -42.851 1.00 39.44 ? 108 ARG A O 1 ATOM 818 C CB . ARG A 1 100 ? 129.539 64.422 -44.488 1.00 41.50 ? 108 ARG A CB 1 ATOM 819 N N . ASN A 1 101 ? 128.363 61.617 -44.104 1.00 40.09 ? 109 ASN A N 1 ATOM 820 C CA . ASN A 1 101 ? 127.381 60.583 -44.457 1.00 39.93 ? 109 ASN A CA 1 ATOM 821 C C . ASN A 1 101 ? 127.393 59.344 -43.537 1.00 38.58 ? 109 ASN A C 1 ATOM 822 O O . ASN A 1 101 ? 127.091 59.460 -42.355 1.00 39.29 ? 109 ASN A O 1 ATOM 823 C CB . ASN A 1 101 ? 127.622 60.159 -45.912 1.00 42.24 ? 109 ASN A CB 1 ATOM 824 C CG . ASN A 1 101 ? 128.468 61.174 -46.695 1.00 43.88 ? 109 ASN A CG 1 ATOM 825 O OD1 . ASN A 1 101 ? 129.432 60.806 -47.373 1.00 45.24 ? 109 ASN A OD1 1 ATOM 826 N ND2 . ASN A 1 101 ? 128.106 62.447 -46.606 1.00 40.94 ? 109 ASN A ND2 1 ATOM 827 N N . THR A 1 102 ? 127.715 58.162 -44.071 1.00 36.53 ? 110 THR A N 1 ATOM 828 C CA . THR A 1 102 ? 127.754 56.945 -43.244 1.00 35.27 ? 110 THR A CA 1 ATOM 829 C C . THR A 1 102 ? 129.175 56.703 -42.719 1.00 33.76 ? 110 THR A C 1 ATOM 830 O O . THR A 1 102 ? 130.096 56.437 -43.487 1.00 33.79 ? 110 THR A O 1 ATOM 831 C CB . THR A 1 102 ? 127.299 55.671 -44.020 1.00 34.64 ? 110 THR A CB 1 ATOM 832 O OG1 . THR A 1 102 ? 128.248 55.362 -45.039 1.00 38.40 ? 110 THR A OG1 1 ATOM 833 C CG2 . THR A 1 102 ? 125.947 55.879 -44.671 1.00 34.24 ? 110 THR A CG2 1 ATOM 834 N N . THR A 1 103 ? 129.343 56.783 -41.405 1.00 32.58 ? 111 THR A N 1 ATOM 835 C CA . THR A 1 103 ? 130.652 56.616 -40.788 1.00 31.89 ? 111 THR A CA 1 ATOM 836 C C . THR A 1 103 ? 131.108 55.182 -40.536 1.00 31.14 ? 111 THR A C 1 ATOM 837 O O . THR A 1 103 ? 130.299 54.293 -40.274 1.00 31.70 ? 111 THR A O 1 ATOM 838 C CB . THR A 1 103 ? 130.715 57.370 -39.448 1.00 31.93 ? 111 THR A CB 1 ATOM 839 O OG1 . THR A 1 103 ? 130.415 58.752 -39.672 1.00 32.94 ? 111 THR A OG1 1 ATOM 840 C CG2 . THR A 1 103 ? 132.105 57.265 -38.837 1.00 33.90 ? 111 THR A CG2 1 ATOM 841 N N . ARG A 1 104 ? 132.419 54.969 -40.629 1.00 30.22 ? 112 ARG A N 1 ATOM 842 C CA . ARG A 1 104 ? 133.025 53.666 -40.370 1.00 30.10 ? 112 ARG A CA 1 ATOM 843 C C . ARG A 1 104 ? 134.165 53.895 -39.392 1.00 31.30 ? 112 ARG A C 1 ATOM 844 O O . ARG A 1 104 ? 134.835 54.928 -39.440 1.00 31.85 ? 112 ARG A O 1 ATOM 845 C CB . ARG A 1 104 ? 133.560 53.030 -41.646 1.00 27.20 ? 112 ARG A CB 1 ATOM 846 C CG . ARG A 1 104 ? 132.481 52.592 -42.607 1.00 27.21 ? 112 ARG A CG 1 ATOM 847 C CD . ARG A 1 104 ? 133.077 51.814 -43.754 1.00 26.76 ? 112 ARG A CD 1 ATOM 848 N NE . ARG A 1 104 ? 133.725 50.597 -43.279 1.00 28.11 ? 112 ARG A NE 1 ATOM 849 C CZ . ARG A 1 104 ? 134.504 49.828 -44.030 1.00 27.68 ? 112 ARG A CZ 1 ATOM 850 N NH1 . ARG A 1 104 ? 134.735 50.156 -45.294 1.00 29.97 ? 112 ARG A NH1 1 ATOM 851 N NH2 . ARG A 1 104 ? 135.048 48.731 -43.522 1.00 26.66 ? 112 ARG A NH2 1 ATOM 852 N N . ARG A 1 105 ? 134.387 52.936 -38.503 1.00 32.27 ? 113 ARG A N 1 ATOM 853 C CA . ARG A 1 105 ? 135.434 53.081 -37.509 1.00 32.39 ? 113 ARG A CA 1 ATOM 854 C C . ARG A 1 105 ? 136.474 51.965 -37.542 1.00 30.70 ? 113 ARG A C 1 ATOM 855 O O . ARG A 1 105 ? 136.150 50.786 -37.720 1.00 29.66 ? 113 ARG A O 1 ATOM 856 C CB . ARG A 1 105 ? 134.805 53.168 -36.118 1.00 35.44 ? 113 ARG A CB 1 ATOM 857 C CG . ARG A 1 105 ? 135.804 53.295 -34.989 1.00 40.56 ? 113 ARG A CG 1 ATOM 858 C CD . ARG A 1 105 ? 135.112 53.214 -33.647 1.00 44.46 ? 113 ARG A CD 1 ATOM 859 N NE . ARG A 1 105 ? 134.232 54.356 -33.430 1.00 50.13 ? 113 ARG A NE 1 ATOM 860 C CZ . ARG A 1 105 ? 133.504 54.531 -32.333 1.00 52.34 ? 113 ARG A CZ 1 ATOM 861 N NH1 . ARG A 1 105 ? 133.554 53.631 -31.360 1.00 53.71 ? 113 ARG A NH1 1 ATOM 862 N NH2 . ARG A 1 105 ? 132.735 55.607 -32.203 1.00 53.90 ? 113 ARG A NH2 1 ATOM 863 N N . PHE A 1 106 ? 137.730 52.367 -37.371 1.00 29.10 ? 114 PHE A N 1 ATOM 864 C CA . PHE A 1 106 ? 138.858 51.450 -37.365 1.00 27.71 ? 114 PHE A CA 1 ATOM 865 C C . PHE A 1 106 ? 139.778 51.863 -36.223 1.00 28.25 ? 114 PHE A C 1 ATOM 866 O O . PHE A 1 106 ? 139.504 52.838 -35.516 1.00 27.51 ? 114 PHE A O 1 ATOM 867 C CB . PHE A 1 106 ? 139.623 51.537 -38.689 1.00 24.12 ? 114 PHE A CB 1 ATOM 868 C CG . PHE A 1 106 ? 138.750 51.401 -39.899 1.00 22.80 ? 114 PHE A CG 1 ATOM 869 C CD1 . PHE A 1 106 ? 138.062 52.507 -40.411 1.00 21.74 ? 114 PHE A CD1 1 ATOM 870 C CD2 . PHE A 1 106 ? 138.591 50.166 -40.519 1.00 22.28 ? 114 PHE A CD2 1 ATOM 871 C CE1 . PHE A 1 106 ? 137.228 52.386 -41.523 1.00 19.69 ? 114 PHE A CE1 1 ATOM 872 C CE2 . PHE A 1 106 ? 137.755 50.031 -41.637 1.00 21.19 ? 114 PHE A CE2 1 ATOM 873 C CZ . PHE A 1 106 ? 137.073 51.144 -42.138 1.00 21.77 ? 114 PHE A CZ 1 ATOM 874 N N . SER A 1 107 ? 140.863 51.120 -36.041 1.00 28.76 ? 115 SER A N 1 ATOM 875 C CA . SER A 1 107 ? 141.819 51.436 -34.990 1.00 29.58 ? 115 SER A CA 1 ATOM 876 C C . SER A 1 107 ? 143.215 51.054 -35.456 1.00 30.06 ? 115 SER A C 1 ATOM 877 O O . SER A 1 107 ? 143.374 50.385 -36.471 1.00 30.96 ? 115 SER A O 1 ATOM 878 C CB . SER A 1 107 ? 141.488 50.671 -33.702 1.00 28.74 ? 115 SER A CB 1 ATOM 879 O OG . SER A 1 107 ? 141.840 49.301 -33.809 1.00 29.62 ? 115 SER A OG 1 ATOM 880 N N . PHE A 1 108 ? 144.219 51.497 -34.712 1.00 30.00 ? 116 PHE A N 1 ATOM 881 C CA . PHE A 1 108 ? 145.607 51.187 -35.010 1.00 29.14 ? 116 PHE A CA 1 ATOM 882 C C . PHE A 1 108 ? 146.418 51.528 -33.766 1.00 29.08 ? 116 PHE A C 1 ATOM 883 O O . PHE A 1 108 ? 145.988 52.340 -32.942 1.00 29.27 ? 116 PHE A O 1 ATOM 884 C CB . PHE A 1 108 ? 146.097 51.986 -36.220 1.00 27.79 ? 116 PHE A CB 1 ATOM 885 C CG . PHE A 1 108 ? 146.145 53.467 -35.996 1.00 28.05 ? 116 PHE A CG 1 ATOM 886 C CD1 . PHE A 1 108 ? 147.090 54.031 -35.133 1.00 27.52 ? 116 PHE A CD1 1 ATOM 887 C CD2 . PHE A 1 108 ? 145.252 54.308 -36.662 1.00 28.26 ? 116 PHE A CD2 1 ATOM 888 C CE1 . PHE A 1 108 ? 147.151 55.419 -34.938 1.00 27.62 ? 116 PHE A CE1 1 ATOM 889 C CE2 . PHE A 1 108 ? 145.300 55.699 -36.478 1.00 27.90 ? 116 PHE A CE2 1 ATOM 890 C CZ . PHE A 1 108 ? 146.252 56.254 -35.614 1.00 27.83 ? 116 PHE A CZ 1 ATOM 891 N N . ILE A 1 109 ? 147.579 50.898 -33.628 1.00 28.13 ? 117 ILE A N 1 ATOM 892 C CA . ILE A 1 109 ? 148.442 51.126 -32.477 1.00 27.35 ? 117 ILE A CA 1 ATOM 893 C C . ILE A 1 109 ? 149.782 51.706 -32.921 1.00 27.25 ? 117 ILE A C 1 ATOM 894 O O . ILE A 1 109 ? 150.565 51.031 -33.593 1.00 26.97 ? 117 ILE A O 1 ATOM 895 C CB . ILE A 1 109 ? 148.704 49.812 -31.744 1.00 27.11 ? 117 ILE A CB 1 ATOM 896 C CG1 . ILE A 1 109 ? 147.379 49.083 -31.521 1.00 28.58 ? 117 ILE A CG1 1 ATOM 897 C CG2 . ILE A 1 109 ? 149.409 50.085 -30.424 1.00 26.77 ? 117 ILE A CG2 1 ATOM 898 C CD1 . ILE A 1 109 ? 147.535 47.643 -31.050 1.00 30.50 ? 117 ILE A CD1 1 ATOM 899 N N . THR A 1 110 ? 150.049 52.954 -32.553 1.00 26.58 ? 118 THR A N 1 ATOM 900 C CA . THR A 1 110 ? 151.302 53.577 -32.942 1.00 28.58 ? 118 THR A CA 1 ATOM 901 C C . THR A 1 110 ? 152.452 52.765 -32.366 1.00 29.01 ? 118 THR A C 1 ATOM 902 O O . THR A 1 110 ? 152.301 52.096 -31.339 1.00 30.08 ? 118 THR A O 1 ATOM 903 C CB . THR A 1 110 ? 151.397 55.024 -32.426 1.00 30.48 ? 118 THR A CB 1 ATOM 904 O OG1 . THR A 1 110 ? 151.333 55.023 -30.994 1.00 32.93 ? 118 THR A OG1 1 ATOM 905 C CG2 . THR A 1 110 ? 150.259 55.863 -32.987 1.00 30.81 ? 118 THR A CG2 1 ATOM 906 N N . PRO A 1 111 ? 153.621 52.810 -33.022 1.00 27.98 ? 119 PRO A N 1 ATOM 907 C CA . PRO A 1 111 ? 154.789 52.065 -32.557 1.00 28.12 ? 119 PRO A CA 1 ATOM 908 C C . PRO A 1 111 ? 155.426 52.729 -31.348 1.00 28.31 ? 119 PRO A C 1 ATOM 909 O O . PRO A 1 111 ? 155.083 53.861 -30.990 1.00 29.70 ? 119 PRO A O 1 ATOM 910 C CB . PRO A 1 111 ? 155.712 52.121 -33.760 1.00 25.89 ? 119 PRO A CB 1 ATOM 911 C CG . PRO A 1 111 ? 155.480 53.523 -34.232 1.00 25.15 ? 119 PRO A CG 1 ATOM 912 C CD . PRO A 1 111 ? 153.965 53.613 -34.210 1.00 26.95 ? 119 PRO A CD 1 ATOM 913 N N . PRO A 1 112 ? 156.350 52.026 -30.685 1.00 27.41 ? 120 PRO A N 1 ATOM 914 C CA . PRO A 1 112 ? 157.010 52.620 -29.523 1.00 28.67 ? 120 PRO A CA 1 ATOM 915 C C . PRO A 1 112 ? 158.093 53.564 -30.047 1.00 29.63 ? 120 PRO A C 1 ATOM 916 O O . PRO A 1 112 ? 158.469 53.490 -31.213 1.00 30.15 ? 120 PRO A O 1 ATOM 917 C CB . PRO A 1 112 ? 157.581 51.407 -28.795 1.00 27.47 ? 120 PRO A CB 1 ATOM 918 C CG . PRO A 1 112 ? 157.882 50.465 -29.911 1.00 27.31 ? 120 PRO A CG 1 ATOM 919 C CD . PRO A 1 112 ? 156.672 50.595 -30.803 1.00 26.65 ? 120 PRO A CD 1 ATOM 920 N N . GLN A 1 113 ? 158.582 54.455 -29.195 1.00 31.13 ? 121 GLN A N 1 ATOM 921 C CA . GLN A 1 113 ? 159.620 55.401 -29.590 1.00 31.91 ? 121 GLN A CA 1 ATOM 922 C C . GLN A 1 113 ? 160.833 54.636 -30.112 1.00 31.51 ? 121 GLN A C 1 ATOM 923 O O . GLN A 1 113 ? 161.070 53.502 -29.704 1.00 31.95 ? 121 GLN A O 1 ATOM 924 C CB . GLN A 1 113 ? 160.002 56.260 -28.388 1.00 32.50 ? 121 GLN A CB 1 ATOM 925 C CG . GLN A 1 113 ? 161.198 57.154 -28.597 1.00 36.24 ? 121 GLN A CG 1 ATOM 926 C CD . GLN A 1 113 ? 161.391 58.104 -27.437 1.00 37.50 ? 121 GLN A CD 1 ATOM 927 O OE1 . GLN A 1 113 ? 161.345 57.695 -26.277 1.00 38.93 ? 121 GLN A OE1 1 ATOM 928 N NE2 . GLN A 1 113 ? 161.607 59.379 -27.741 1.00 38.35 ? 121 GLN A NE2 1 ATOM 929 N N . THR A 1 114 ? 161.594 55.241 -31.019 1.00 31.09 ? 122 THR A N 1 ATOM 930 C CA . THR A 1 114 ? 162.765 54.560 -31.569 1.00 30.39 ? 122 THR A CA 1 ATOM 931 C C . THR A 1 114 ? 163.792 54.330 -30.470 1.00 30.01 ? 122 THR A C 1 ATOM 932 O O . THR A 1 114 ? 164.059 55.218 -29.661 1.00 30.54 ? 122 THR A O 1 ATOM 933 C CB . THR A 1 114 ? 163.420 55.365 -32.719 1.00 29.87 ? 122 THR A CB 1 ATOM 934 O OG1 . THR A 1 114 ? 164.007 56.565 -32.202 1.00 30.59 ? 122 THR A OG1 1 ATOM 935 C CG2 . THR A 1 114 ? 162.381 55.728 -33.764 1.00 29.26 ? 122 THR A CG2 1 ATOM 936 N N . GLY A 1 115 ? 164.353 53.125 -30.440 1.00 29.65 ? 123 GLY A N 1 ATOM 937 C CA . GLY A 1 115 ? 165.333 52.781 -29.431 1.00 28.28 ? 123 GLY A CA 1 ATOM 938 C C . GLY A 1 115 ? 166.262 51.665 -29.866 1.00 29.28 ? 123 GLY A C 1 ATOM 939 O O . GLY A 1 115 ? 166.015 50.974 -30.849 1.00 29.15 ? 123 GLY A O 1 ATOM 940 N N . LEU A 1 116 ? 167.333 51.475 -29.107 1.00 30.78 ? 124 LEU A N 1 ATOM 941 C CA . LEU A 1 116 ? 168.326 50.460 -29.416 1.00 31.47 ? 124 LEU A CA 1 ATOM 942 C C . LEU A 1 116 ? 167.845 49.018 -29.286 1.00 31.79 ? 124 LEU A C 1 ATOM 943 O O . LEU A 1 116 ? 168.122 48.195 -30.154 1.00 33.61 ? 124 LEU A O 1 ATOM 944 C CB . LEU A 1 116 ? 169.556 50.673 -28.544 1.00 31.15 ? 124 LEU A CB 1 ATOM 945 C CG . LEU A 1 116 ? 170.825 50.003 -29.054 1.00 33.98 ? 124 LEU A CG 1 ATOM 946 C CD1 . LEU A 1 116 ? 171.067 50.380 -30.506 1.00 34.11 ? 124 LEU A CD1 1 ATOM 947 C CD2 . LEU A 1 116 ? 171.984 50.451 -28.190 1.00 35.96 ? 124 LEU A CD2 1 ATOM 948 N N . ASP A 1 117 ? 167.131 48.702 -28.212 1.00 31.07 ? 125 ASP A N 1 ATOM 949 C CA . ASP A 1 117 ? 166.643 47.339 -28.019 1.00 31.43 ? 125 ASP A CA 1 ATOM 950 C C . ASP A 1 117 ? 165.130 47.209 -28.112 1.00 31.34 ? 125 ASP A C 1 ATOM 951 O O . ASP A 1 117 ? 164.550 46.284 -27.532 1.00 32.64 ? 125 ASP A O 1 ATOM 952 C CB . ASP A 1 117 ? 167.086 46.794 -26.660 1.00 31.16 ? 125 ASP A CB 1 ATOM 953 C CG . ASP A 1 117 ? 168.572 46.597 -26.573 1.00 31.49 ? 125 ASP A CG 1 ATOM 954 O OD1 . ASP A 1 117 ? 169.112 45.823 -27.393 1.00 32.45 ? 125 ASP A OD1 1 ATOM 955 O OD2 . ASP A 1 117 ? 169.195 47.216 -25.685 1.00 30.39 ? 125 ASP A OD2 1 ATOM 956 N N . VAL A 1 118 ? 164.486 48.122 -28.832 1.00 29.57 ? 126 VAL A N 1 ATOM 957 C CA . VAL A 1 118 ? 163.036 48.068 -28.957 1.00 27.22 ? 126 VAL A CA 1 ATOM 958 C C . VAL A 1 118 ? 162.595 46.918 -29.850 1.00 25.70 ? 126 VAL A C 1 ATOM 959 O O . VAL A 1 118 ? 162.964 46.853 -31.024 1.00 26.59 ? 126 VAL A O 1 ATOM 960 C CB . VAL A 1 118 ? 162.474 49.373 -29.540 1.00 26.64 ? 126 VAL A CB 1 ATOM 961 C CG1 . VAL A 1 118 ? 160.971 49.261 -29.680 1.00 25.37 ? 126 VAL A CG1 1 ATOM 962 C CG2 . VAL A 1 118 ? 162.834 50.541 -28.643 1.00 25.26 ? 126 VAL A CG2 1 ATOM 963 N N . PRO A 1 119 ? 161.798 45.985 -29.304 1.00 24.87 ? 127 PRO A N 1 ATOM 964 C CA . PRO A 1 119 ? 161.327 44.849 -30.104 1.00 24.80 ? 127 PRO A CA 1 ATOM 965 C C . PRO A 1 119 ? 160.163 45.234 -31.022 1.00 24.06 ? 127 PRO A C 1 ATOM 966 O O . PRO A 1 119 ? 159.345 46.097 -30.690 1.00 24.13 ? 127 PRO A O 1 ATOM 967 C CB . PRO A 1 119 ? 160.921 43.828 -29.044 1.00 22.51 ? 127 PRO A CB 1 ATOM 968 C CG . PRO A 1 119 ? 160.394 44.699 -27.955 1.00 24.17 ? 127 PRO A CG 1 ATOM 969 C CD . PRO A 1 119 ? 161.428 45.814 -27.887 1.00 24.19 ? 127 PRO A CD 1 ATOM 970 N N . TYR A 1 120 ? 160.101 44.591 -32.179 1.00 23.23 ? 128 TYR A N 1 ATOM 971 C CA . TYR A 1 120 ? 159.039 44.856 -33.134 1.00 23.93 ? 128 TYR A CA 1 ATOM 972 C C . TYR A 1 120 ? 159.044 43.755 -34.175 1.00 23.74 ? 128 TYR A C 1 ATOM 973 O O . TYR A 1 120 ? 160.104 43.253 -34.548 1.00 25.50 ? 128 TYR A O 1 ATOM 974 C CB . TYR A 1 120 ? 159.263 46.198 -33.815 1.00 23.98 ? 128 TYR A CB 1 ATOM 975 C CG . TYR A 1 120 ? 157.991 46.843 -34.302 1.00 24.55 ? 128 TYR A CG 1 ATOM 976 C CD1 . TYR A 1 120 ? 157.168 47.545 -33.424 1.00 23.92 ? 128 TYR A CD1 1 ATOM 977 C CD2 . TYR A 1 120 ? 157.615 46.766 -35.644 1.00 25.00 ? 128 TYR A CD2 1 ATOM 978 C CE1 . TYR A 1 120 ? 156.003 48.166 -33.867 1.00 24.29 ? 128 TYR A CE1 1 ATOM 979 C CE2 . TYR A 1 120 ? 156.448 47.379 -36.099 1.00 25.07 ? 128 TYR A CE2 1 ATOM 980 C CZ . TYR A 1 120 ? 155.649 48.080 -35.206 1.00 25.88 ? 128 TYR A CZ 1 ATOM 981 O OH . TYR A 1 120 ? 154.505 48.703 -35.654 1.00 27.29 ? 128 TYR A OH 1 ATOM 982 N N . THR A 1 121 ? 157.868 43.360 -34.639 1.00 23.82 ? 129 THR A N 1 ATOM 983 C CA . THR A 1 121 ? 157.803 42.307 -35.639 1.00 24.62 ? 129 THR A CA 1 ATOM 984 C C . THR A 1 121 ? 157.089 42.775 -36.913 1.00 24.53 ? 129 THR A C 1 ATOM 985 O O . THR A 1 121 ? 155.913 43.149 -36.893 1.00 25.44 ? 129 THR A O 1 ATOM 986 C CB . THR A 1 121 ? 157.160 41.019 -35.041 1.00 24.43 ? 129 THR A CB 1 ATOM 987 O OG1 . THR A 1 121 ? 156.363 40.365 -36.036 1.00 24.92 ? 129 THR A OG1 1 ATOM 988 C CG2 . THR A 1 121 ? 156.343 41.345 -33.797 1.00 23.78 ? 129 THR A CG2 1 ATOM 989 N N . PHE A 1 122 ? 157.845 42.769 -38.012 1.00 23.63 ? 130 PHE A N 1 ATOM 990 C CA . PHE A 1 122 ? 157.389 43.210 -39.333 1.00 21.49 ? 130 PHE A CA 1 ATOM 991 C C . PHE A 1 122 ? 156.933 42.059 -40.213 1.00 21.79 ? 130 PHE A C 1 ATOM 992 O O . PHE A 1 122 ? 157.473 40.953 -40.148 1.00 22.15 ? 130 PHE A O 1 ATOM 993 C CB . PHE A 1 122 ? 158.529 43.912 -40.085 1.00 19.61 ? 130 PHE A CB 1 ATOM 994 C CG . PHE A 1 122 ? 158.964 45.221 -39.489 1.00 19.27 ? 130 PHE A CG 1 ATOM 995 C CD1 . PHE A 1 122 ? 158.232 46.376 -39.715 1.00 17.95 ? 130 PHE A CD1 1 ATOM 996 C CD2 . PHE A 1 122 ? 160.148 45.310 -38.750 1.00 18.24 ? 130 PHE A CD2 1 ATOM 997 C CE1 . PHE A 1 122 ? 158.675 47.601 -39.221 1.00 18.31 ? 130 PHE A CE1 1 ATOM 998 C CE2 . PHE A 1 122 ? 160.593 46.528 -38.254 1.00 16.67 ? 130 PHE A CE2 1 ATOM 999 C CZ . PHE A 1 122 ? 159.862 47.671 -38.490 1.00 17.30 ? 130 PHE A CZ 1 ATOM 1000 N N . GLY A 1 123 ? 155.950 42.336 -41.059 1.00 22.14 ? 131 GLY A N 1 ATOM 1001 C CA . GLY A 1 123 ? 155.475 41.325 -41.984 1.00 22.33 ? 131 GLY A CA 1 ATOM 1002 C C . GLY A 1 123 ? 156.116 41.583 -43.346 1.00 22.11 ? 131 GLY A C 1 ATOM 1003 O O . GLY A 1 123 ? 156.492 42.720 -43.653 1.00 21.54 ? 131 GLY A O 1 ATOM 1004 N N . LEU A 1 124 ? 156.263 40.539 -44.156 1.00 21.20 ? 132 LEU A N 1 ATOM 1005 C CA . LEU A 1 124 ? 156.845 40.682 -45.482 1.00 21.68 ? 132 LEU A CA 1 ATOM 1006 C C . LEU A 1 124 ? 155.934 40.053 -46.527 1.00 22.20 ? 132 LEU A C 1 ATOM 1007 O O . LEU A 1 124 ? 155.702 38.848 -46.526 1.00 21.44 ? 132 LEU A O 1 ATOM 1008 C CB . LEU A 1 124 ? 158.230 40.048 -45.518 1.00 21.00 ? 132 LEU A CB 1 ATOM 1009 C CG . LEU A 1 124 ? 159.261 40.980 -44.878 1.00 23.39 ? 132 LEU A CG 1 ATOM 1010 C CD1 . LEU A 1 124 ? 160.252 40.195 -44.048 1.00 26.64 ? 132 LEU A CD1 1 ATOM 1011 C CD2 . LEU A 1 124 ? 159.952 41.771 -45.969 1.00 23.11 ? 132 LEU A CD2 1 ATOM 1012 N N . ILE A 1 125 ? 155.403 40.895 -47.406 1.00 21.65 ? 133 ILE A N 1 ATOM 1013 C CA . ILE A 1 125 ? 154.509 40.454 -48.460 1.00 21.91 ? 133 ILE A CA 1 ATOM 1014 C C . ILE A 1 125 ? 154.945 41.136 -49.752 1.00 22.62 ? 133 ILE A C 1 ATOM 1015 O O . ILE A 1 125 ? 155.234 42.338 -49.762 1.00 22.91 ? 133 ILE A O 1 ATOM 1016 C CB . ILE A 1 125 ? 153.045 40.841 -48.140 1.00 20.87 ? 133 ILE A CB 1 ATOM 1017 C CG1 . ILE A 1 125 ? 152.601 40.162 -46.843 1.00 20.20 ? 133 ILE A CG1 1 ATOM 1018 C CG2 . ILE A 1 125 ? 152.134 40.439 -49.278 1.00 19.34 ? 133 ILE A CG2 1 ATOM 1019 C CD1 . ILE A 1 125 ? 151.209 40.569 -46.376 1.00 19.03 ? 133 ILE A CD1 1 ATOM 1020 N N . GLY A 1 126 ? 155.010 40.363 -50.833 1.00 22.39 ? 134 GLY A N 1 ATOM 1021 C CA . GLY A 1 126 ? 155.413 40.917 -52.113 1.00 22.01 ? 134 GLY A CA 1 ATOM 1022 C C . GLY A 1 126 ? 154.613 40.326 -53.258 1.00 21.73 ? 134 GLY A C 1 ATOM 1023 O O . GLY A 1 126 ? 154.314 39.130 -53.248 1.00 22.68 ? 134 GLY A O 1 ATOM 1024 N N . ASP A 1 127 ? 154.261 41.156 -54.240 1.00 20.88 ? 135 ASP A N 1 ATOM 1025 C CA . ASP A 1 127 ? 153.503 40.702 -55.405 1.00 20.20 ? 135 ASP A CA 1 ATOM 1026 C C . ASP A 1 127 ? 152.219 40.009 -54.971 1.00 20.79 ? 135 ASP A C 1 ATOM 1027 O O . ASP A 1 127 ? 151.922 38.903 -55.423 1.00 20.07 ? 135 ASP A O 1 ATOM 1028 C CB . ASP A 1 127 ? 154.356 39.737 -56.233 1.00 19.03 ? 135 ASP A CB 1 ATOM 1029 C CG . ASP A 1 127 ? 155.683 40.346 -56.643 1.00 19.47 ? 135 ASP A CG 1 ATOM 1030 O OD1 . ASP A 1 127 ? 156.506 40.611 -55.752 1.00 19.41 ? 135 ASP A OD1 1 ATOM 1031 O OD2 . ASP A 1 127 ? 155.907 40.568 -57.854 1.00 20.86 ? 135 ASP A OD2 1 ATOM 1032 N N . LEU A 1 128 ? 151.461 40.666 -54.098 1.00 20.78 ? 136 LEU A N 1 ATOM 1033 C CA . LEU A 1 128 ? 150.220 40.107 -53.578 1.00 22.11 ? 136 LEU A CA 1 ATOM 1034 C C . LEU A 1 128 ? 149.206 39.751 -54.665 1.00 23.25 ? 136 LEU A C 1 ATOM 1035 O O . LEU A 1 128 ? 148.879 38.579 -54.860 1.00 23.92 ? 136 LEU A O 1 ATOM 1036 C CB . LEU A 1 128 ? 149.589 41.079 -52.571 1.00 19.78 ? 136 LEU A CB 1 ATOM 1037 C CG . LEU A 1 128 ? 148.317 40.606 -51.864 1.00 18.56 ? 136 LEU A CG 1 ATOM 1038 C CD1 . LEU A 1 128 ? 148.519 39.209 -51.295 1.00 16.20 ? 136 LEU A CD1 1 ATOM 1039 C CD2 . LEU A 1 128 ? 147.966 41.587 -50.764 1.00 19.05 ? 136 LEU A CD2 1 ATOM 1040 N N . GLY A 1 129 ? 148.718 40.757 -55.381 1.00 24.38 ? 137 GLY A N 1 ATOM 1041 C CA . GLY A 1 129 ? 147.735 40.497 -56.418 1.00 23.56 ? 137 GLY A CA 1 ATOM 1042 C C . GLY A 1 129 ? 146.378 40.238 -55.789 1.00 23.34 ? 137 GLY A C 1 ATOM 1043 O O . GLY A 1 129 ? 146.150 40.607 -54.638 1.00 22.69 ? 137 GLY A O 1 ATOM 1044 N N . GLN A 1 130 ? 145.474 39.607 -56.530 1.00 23.67 ? 138 GLN A N 1 ATOM 1045 C CA . GLN A 1 130 ? 144.149 39.322 -55.997 1.00 24.34 ? 138 GLN A CA 1 ATOM 1046 C C . GLN A 1 130 ? 143.573 37.995 -56.491 1.00 25.39 ? 138 GLN A C 1 ATOM 1047 O O . GLN A 1 130 ? 142.403 37.904 -56.858 1.00 25.84 ? 138 GLN A O 1 ATOM 1048 C CB . GLN A 1 130 ? 143.194 40.475 -56.330 1.00 23.81 ? 138 GLN A CB 1 ATOM 1049 C CG . GLN A 1 130 ? 143.028 40.775 -57.814 1.00 24.19 ? 138 GLN A CG 1 ATOM 1050 C CD . GLN A 1 130 ? 142.335 42.109 -58.048 1.00 24.93 ? 138 GLN A CD 1 ATOM 1051 O OE1 . GLN A 1 130 ? 142.987 43.134 -58.266 1.00 25.24 ? 138 GLN A OE1 1 ATOM 1052 N NE2 . GLN A 1 130 ? 141.009 42.105 -57.978 1.00 24.17 ? 138 GLN A NE2 1 ATOM 1053 N N . SER A 1 131 ? 144.411 36.965 -56.499 1.00 26.31 ? 139 SER A N 1 ATOM 1054 C CA . SER A 1 131 ? 143.997 35.635 -56.919 1.00 26.46 ? 139 SER A CA 1 ATOM 1055 C C . SER A 1 131 ? 143.664 34.874 -55.640 1.00 28.12 ? 139 SER A C 1 ATOM 1056 O O . SER A 1 131 ? 143.997 35.320 -54.540 1.00 27.43 ? 139 SER A O 1 ATOM 1057 C CB . SER A 1 131 ? 145.138 34.932 -57.644 1.00 25.23 ? 139 SER A CB 1 ATOM 1058 O OG . SER A 1 131 ? 146.225 34.735 -56.759 1.00 24.39 ? 139 SER A OG 1 ATOM 1059 N N . PHE A 1 132 ? 143.009 33.729 -55.781 1.00 28.40 ? 140 PHE A N 1 ATOM 1060 C CA . PHE A 1 132 ? 142.653 32.940 -54.616 1.00 28.03 ? 140 PHE A CA 1 ATOM 1061 C C . PHE A 1 132 ? 143.858 32.695 -53.731 1.00 27.54 ? 140 PHE A C 1 ATOM 1062 O O . PHE A 1 132 ? 143.751 32.702 -52.510 1.00 29.15 ? 140 PHE A O 1 ATOM 1063 C CB . PHE A 1 132 ? 142.027 31.622 -55.054 1.00 27.87 ? 140 PHE A CB 1 ATOM 1064 C CG . PHE A 1 132 ? 140.624 31.776 -55.559 1.00 29.27 ? 140 PHE A CG 1 ATOM 1065 C CD1 . PHE A 1 132 ? 139.593 32.097 -54.678 1.00 29.63 ? 140 PHE A CD1 1 ATOM 1066 C CD2 . PHE A 1 132 ? 140.335 31.646 -56.917 1.00 29.33 ? 140 PHE A CD2 1 ATOM 1067 C CE1 . PHE A 1 132 ? 138.292 32.290 -55.143 1.00 30.11 ? 140 PHE A CE1 1 ATOM 1068 C CE2 . PHE A 1 132 ? 139.036 31.836 -57.393 1.00 29.31 ? 140 PHE A CE2 1 ATOM 1069 C CZ . PHE A 1 132 ? 138.015 32.158 -56.505 1.00 29.01 ? 140 PHE A CZ 1 ATOM 1070 N N . ASP A 1 133 ? 145.014 32.500 -54.344 1.00 27.55 ? 141 ASP A N 1 ATOM 1071 C CA . ASP A 1 133 ? 146.227 32.271 -53.577 1.00 27.91 ? 141 ASP A CA 1 ATOM 1072 C C . ASP A 1 133 ? 146.537 33.490 -52.705 1.00 27.72 ? 141 ASP A C 1 ATOM 1073 O O . ASP A 1 133 ? 146.984 33.357 -51.561 1.00 27.49 ? 141 ASP A O 1 ATOM 1074 C CB . ASP A 1 133 ? 147.390 31.974 -54.527 1.00 28.94 ? 141 ASP A CB 1 ATOM 1075 C CG . ASP A 1 133 ? 147.205 30.666 -55.271 1.00 30.11 ? 141 ASP A CG 1 ATOM 1076 O OD1 . ASP A 1 133 ? 147.260 29.607 -54.614 1.00 32.21 ? 141 ASP A OD1 1 ATOM 1077 O OD2 . ASP A 1 133 ? 146.995 30.692 -56.504 1.00 30.66 ? 141 ASP A OD2 1 ATOM 1078 N N . SER A 1 134 ? 146.279 34.675 -53.246 1.00 26.74 ? 142 SER A N 1 ATOM 1079 C CA . SER A 1 134 ? 146.522 35.918 -52.528 1.00 26.67 ? 142 SER A CA 1 ATOM 1080 C C . SER A 1 134 ? 145.729 35.974 -51.218 1.00 26.84 ? 142 SER A C 1 ATOM 1081 O O . SER A 1 134 ? 146.244 36.411 -50.184 1.00 25.44 ? 142 SER A O 1 ATOM 1082 C CB . SER A 1 134 ? 146.128 37.105 -53.406 1.00 26.95 ? 142 SER A CB 1 ATOM 1083 O OG . SER A 1 134 ? 146.639 36.957 -54.718 1.00 28.12 ? 142 SER A OG 1 ATOM 1084 N N . ASN A 1 135 ? 144.476 35.526 -51.268 1.00 27.41 ? 143 ASN A N 1 ATOM 1085 C CA . ASN A 1 135 ? 143.600 35.539 -50.096 1.00 25.92 ? 143 ASN A CA 1 ATOM 1086 C C . ASN A 1 135 ? 144.125 34.624 -49.005 1.00 24.50 ? 143 ASN A C 1 ATOM 1087 O O . ASN A 1 135 ? 144.022 34.943 -47.819 1.00 24.11 ? 143 ASN A O 1 ATOM 1088 C CB . ASN A 1 135 ? 142.174 35.132 -50.484 1.00 25.92 ? 143 ASN A CB 1 ATOM 1089 C CG . ASN A 1 135 ? 141.169 35.428 -49.387 1.00 28.59 ? 143 ASN A CG 1 ATOM 1090 O OD1 . ASN A 1 135 ? 141.274 36.456 -48.707 1.00 27.19 ? 143 ASN A OD1 1 ATOM 1091 N ND2 . ASN A 1 135 ? 140.187 34.540 -49.225 1.00 30.54 ? 143 ASN A ND2 1 ATOM 1092 N N . THR A 1 136 ? 144.690 33.489 -49.410 1.00 23.04 ? 144 THR A N 1 ATOM 1093 C CA . THR A 1 136 ? 145.238 32.530 -48.461 1.00 21.81 ? 144 THR A CA 1 ATOM 1094 C C . THR A 1 136 ? 146.435 33.159 -47.782 1.00 21.63 ? 144 THR A C 1 ATOM 1095 O O . THR A 1 136 ? 146.530 33.177 -46.555 1.00 22.72 ? 144 THR A O 1 ATOM 1096 C CB . THR A 1 136 ? 145.700 31.249 -49.161 1.00 21.89 ? 144 THR A CB 1 ATOM 1097 O OG1 . THR A 1 136 ? 144.577 30.624 -49.791 1.00 23.21 ? 144 THR A OG1 1 ATOM 1098 C CG2 . THR A 1 136 ? 146.321 30.290 -48.161 1.00 19.76 ? 144 THR A CG2 1 ATOM 1099 N N . THR A 1 137 ? 147.353 33.684 -48.585 1.00 21.77 ? 145 THR A N 1 ATOM 1100 C CA . THR A 1 137 ? 148.541 34.317 -48.035 1.00 21.04 ? 145 THR A CA 1 ATOM 1101 C C . THR A 1 137 ? 148.150 35.359 -47.001 1.00 20.88 ? 145 THR A C 1 ATOM 1102 O O . THR A 1 137 ? 148.668 35.353 -45.887 1.00 21.71 ? 145 THR A O 1 ATOM 1103 C CB . THR A 1 137 ? 149.380 34.999 -49.128 1.00 21.53 ? 145 THR A CB 1 ATOM 1104 O OG1 . THR A 1 137 ? 149.733 34.039 -50.129 1.00 23.41 ? 145 THR A OG1 1 ATOM 1105 C CG2 . THR A 1 137 ? 150.656 35.575 -48.535 1.00 20.75 ? 145 THR A CG2 1 ATOM 1106 N N . LEU A 1 138 ? 147.231 36.251 -47.355 1.00 21.28 ? 146 LEU A N 1 ATOM 1107 C CA . LEU A 1 138 ? 146.814 37.281 -46.412 1.00 22.92 ? 146 LEU A CA 1 ATOM 1108 C C . LEU A 1 138 ? 146.232 36.668 -45.137 1.00 24.22 ? 146 LEU A C 1 ATOM 1109 O O . LEU A 1 138 ? 146.461 37.190 -44.040 1.00 24.17 ? 146 LEU A O 1 ATOM 1110 C CB . LEU A 1 138 ? 145.795 38.233 -47.057 1.00 24.32 ? 146 LEU A CB 1 ATOM 1111 C CG . LEU A 1 138 ? 145.379 39.461 -46.227 1.00 25.30 ? 146 LEU A CG 1 ATOM 1112 C CD1 . LEU A 1 138 ? 146.612 40.243 -45.764 1.00 24.64 ? 146 LEU A CD1 1 ATOM 1113 C CD2 . LEU A 1 138 ? 144.473 40.356 -47.062 1.00 25.51 ? 146 LEU A CD2 1 ATOM 1114 N N . SER A 1 139 ? 145.487 35.568 -45.276 1.00 24.46 ? 147 SER A N 1 ATOM 1115 C CA . SER A 1 139 ? 144.895 34.896 -44.119 1.00 24.62 ? 147 SER A CA 1 ATOM 1116 C C . SER A 1 139 ? 145.982 34.392 -43.188 1.00 25.37 ? 147 SER A C 1 ATOM 1117 O O . SER A 1 139 ? 145.937 34.648 -41.981 1.00 25.94 ? 147 SER A O 1 ATOM 1118 C CB . SER A 1 139 ? 144.037 33.709 -44.545 1.00 24.64 ? 147 SER A CB 1 ATOM 1119 O OG . SER A 1 139 ? 142.965 34.115 -45.369 1.00 27.78 ? 147 SER A OG 1 ATOM 1120 N N . HIS A 1 140 ? 146.953 33.671 -43.742 1.00 24.27 ? 148 HIS A N 1 ATOM 1121 C CA . HIS A 1 140 ? 148.044 33.145 -42.932 1.00 26.65 ? 148 HIS A CA 1 ATOM 1122 C C . HIS A 1 140 ? 148.742 34.259 -42.159 1.00 27.33 ? 148 HIS A C 1 ATOM 1123 O O . HIS A 1 140 ? 149.151 34.064 -41.012 1.00 27.92 ? 148 HIS A O 1 ATOM 1124 C CB . HIS A 1 140 ? 149.061 32.395 -43.798 1.00 28.95 ? 148 HIS A CB 1 ATOM 1125 C CG . HIS A 1 140 ? 148.607 31.030 -44.215 1.00 32.03 ? 148 HIS A CG 1 ATOM 1126 N ND1 . HIS A 1 140 ? 149.428 29.923 -44.154 1.00 32.52 ? 148 HIS A ND1 1 ATOM 1127 C CD2 . HIS A 1 140 ? 147.423 30.594 -44.710 1.00 32.64 ? 148 HIS A CD2 1 ATOM 1128 C CE1 . HIS A 1 140 ? 148.768 28.866 -44.594 1.00 33.42 ? 148 HIS A CE1 1 ATOM 1129 N NE2 . HIS A 1 140 ? 147.550 29.246 -44.938 1.00 33.06 ? 148 HIS A NE2 1 ATOM 1130 N N . TYR A 1 141 ? 148.871 35.428 -42.781 1.00 27.31 ? 149 TYR A N 1 ATOM 1131 C CA . TYR A 1 141 ? 149.509 36.558 -42.114 1.00 27.08 ? 149 TYR A CA 1 ATOM 1132 C C . TYR A 1 141 ? 148.676 37.008 -40.909 1.00 28.51 ? 149 TYR A C 1 ATOM 1133 O O . TYR A 1 141 ? 149.216 37.302 -39.839 1.00 28.01 ? 149 TYR A O 1 ATOM 1134 C CB . TYR A 1 141 ? 149.698 37.739 -43.081 1.00 23.43 ? 149 TYR A CB 1 ATOM 1135 C CG . TYR A 1 141 ? 150.279 38.961 -42.404 1.00 19.95 ? 149 TYR A CG 1 ATOM 1136 C CD1 . TYR A 1 141 ? 151.572 38.945 -41.877 1.00 18.57 ? 149 TYR A CD1 1 ATOM 1137 C CD2 . TYR A 1 141 ? 149.512 40.107 -42.221 1.00 19.20 ? 149 TYR A CD2 1 ATOM 1138 C CE1 . TYR A 1 141 ? 152.080 40.034 -41.181 1.00 16.53 ? 149 TYR A CE1 1 ATOM 1139 C CE2 . TYR A 1 141 ? 150.014 41.211 -41.523 1.00 17.42 ? 149 TYR A CE2 1 ATOM 1140 C CZ . TYR A 1 141 ? 151.298 41.162 -41.005 1.00 17.69 ? 149 TYR A CZ 1 ATOM 1141 O OH . TYR A 1 141 ? 151.802 42.234 -40.301 1.00 15.63 ? 149 TYR A OH 1 ATOM 1142 N N . GLU A 1 142 ? 147.359 37.049 -41.085 1.00 30.22 ? 150 GLU A N 1 ATOM 1143 C CA . GLU A 1 142 ? 146.456 37.461 -40.018 1.00 32.78 ? 150 GLU A CA 1 ATOM 1144 C C . GLU A 1 142 ? 146.427 36.463 -38.874 1.00 33.28 ? 150 GLU A C 1 ATOM 1145 O O . GLU A 1 142 ? 146.303 36.849 -37.721 1.00 34.24 ? 150 GLU A O 1 ATOM 1146 C CB . GLU A 1 142 ? 145.033 37.617 -40.555 1.00 34.60 ? 150 GLU A CB 1 ATOM 1147 C CG . GLU A 1 142 ? 144.881 38.644 -41.655 1.00 38.29 ? 150 GLU A CG 1 ATOM 1148 C CD . GLU A 1 142 ? 143.482 38.649 -42.246 1.00 40.35 ? 150 GLU A CD 1 ATOM 1149 O OE1 . GLU A 1 142 ? 143.014 37.572 -42.688 1.00 41.06 ? 150 GLU A OE1 1 ATOM 1150 O OE2 . GLU A 1 142 ? 142.852 39.729 -42.267 1.00 41.09 ? 150 GLU A OE2 1 ATOM 1151 N N . LEU A 1 143 ? 146.542 35.180 -39.191 1.00 35.27 ? 151 LEU A N 1 ATOM 1152 C CA . LEU A 1 143 ? 146.488 34.148 -38.162 1.00 36.36 ? 151 LEU A CA 1 ATOM 1153 C C . LEU A 1 143 ? 147.835 33.786 -37.555 1.00 37.05 ? 151 LEU A C 1 ATOM 1154 O O . LEU A 1 143 ? 147.899 32.977 -36.631 1.00 38.33 ? 151 LEU A O 1 ATOM 1155 C CB . LEU A 1 143 ? 145.823 32.886 -38.722 1.00 35.82 ? 151 LEU A CB 1 ATOM 1156 C CG . LEU A 1 143 ? 144.419 33.096 -39.298 1.00 35.51 ? 151 LEU A CG 1 ATOM 1157 C CD1 . LEU A 1 143 ? 143.846 31.760 -39.741 1.00 34.17 ? 151 LEU A CD1 1 ATOM 1158 C CD2 . LEU A 1 143 ? 143.518 33.748 -38.254 1.00 33.94 ? 151 LEU A CD2 1 ATOM 1159 N N . SER A 1 144 ? 148.907 34.379 -38.065 1.00 37.60 ? 152 SER A N 1 ATOM 1160 C CA . SER A 1 144 ? 150.241 34.090 -37.543 1.00 39.06 ? 152 SER A CA 1 ATOM 1161 C C . SER A 1 144 ? 150.279 34.183 -36.019 1.00 39.75 ? 152 SER A C 1 ATOM 1162 O O . SER A 1 144 ? 149.894 35.201 -35.450 1.00 39.82 ? 152 SER A O 1 ATOM 1163 C CB . SER A 1 144 ? 151.264 35.069 -38.127 1.00 39.25 ? 152 SER A CB 1 ATOM 1164 O OG . SER A 1 144 ? 152.546 34.866 -37.556 1.00 39.33 ? 152 SER A OG 1 ATOM 1165 N N . PRO A 1 145 ? 150.740 33.118 -35.336 1.00 40.92 ? 153 PRO A N 1 ATOM 1166 C CA . PRO A 1 145 ? 150.797 33.172 -33.870 1.00 41.75 ? 153 PRO A CA 1 ATOM 1167 C C . PRO A 1 145 ? 151.555 34.415 -33.389 1.00 43.32 ? 153 PRO A C 1 ATOM 1168 O O . PRO A 1 145 ? 151.097 35.115 -32.481 1.00 44.87 ? 153 PRO A O 1 ATOM 1169 C CB . PRO A 1 145 ? 151.488 31.857 -33.495 1.00 40.50 ? 153 PRO A CB 1 ATOM 1170 C CG . PRO A 1 145 ? 152.289 31.516 -34.716 1.00 41.94 ? 153 PRO A CG 1 ATOM 1171 C CD . PRO A 1 145 ? 151.344 31.873 -35.839 1.00 40.91 ? 153 PRO A CD 1 ATOM 1172 N N . LYS A 1 146 ? 152.713 34.685 -33.992 1.00 44.23 ? 154 LYS A N 1 ATOM 1173 C CA . LYS A 1 146 ? 153.493 35.877 -33.651 1.00 44.97 ? 154 LYS A CA 1 ATOM 1174 C C . LYS A 1 146 ? 152.950 36.960 -34.575 1.00 43.55 ? 154 LYS A C 1 ATOM 1175 O O . LYS A 1 146 ? 153.350 37.068 -35.728 1.00 45.44 ? 154 LYS A O 1 ATOM 1176 C CB . LYS A 1 146 ? 154.989 35.645 -33.901 1.00 46.81 ? 154 LYS A CB 1 ATOM 1177 C CG . LYS A 1 146 ? 155.293 34.730 -35.090 1.00 50.14 ? 154 LYS A CG 1 ATOM 1178 C CD . LYS A 1 146 ? 156.792 34.416 -35.201 1.00 53.44 ? 154 LYS A CD 1 ATOM 1179 C CE . LYS A 1 146 ? 157.051 33.340 -36.251 1.00 54.12 ? 154 LYS A CE 1 ATOM 1180 N NZ . LYS A 1 146 ? 156.422 33.679 -37.570 1.00 56.62 ? 154 LYS A NZ 1 ATOM 1181 N N . LYS A 1 147 ? 152.011 37.740 -34.063 1.00 40.66 ? 155 LYS A N 1 ATOM 1182 C CA . LYS A 1 147 ? 151.364 38.785 -34.838 1.00 38.89 ? 155 LYS A CA 1 ATOM 1183 C C . LYS A 1 147 ? 152.251 39.903 -35.391 1.00 35.92 ? 155 LYS A C 1 ATOM 1184 O O . LYS A 1 147 ? 153.029 40.516 -34.666 1.00 34.47 ? 155 LYS A O 1 ATOM 1185 C CB . LYS A 1 147 ? 150.246 39.376 -33.992 1.00 43.03 ? 155 LYS A CB 1 ATOM 1186 C CG . LYS A 1 147 ? 150.528 39.321 -32.491 1.00 48.31 ? 155 LYS A CG 1 ATOM 1187 C CD . LYS A 1 147 ? 151.675 40.253 -32.063 1.00 53.30 ? 155 LYS A CD 1 ATOM 1188 C CE . LYS A 1 147 ? 153.075 39.632 -32.204 1.00 55.25 ? 155 LYS A CE 1 ATOM 1189 N NZ . LYS A 1 147 ? 154.150 40.617 -31.837 1.00 53.02 ? 155 LYS A NZ 1 ATOM 1190 N N . GLY A 1 148 ? 152.119 40.164 -36.689 1.00 33.28 ? 156 GLY A N 1 ATOM 1191 C CA . GLY A 1 148 ? 152.898 41.214 -37.320 1.00 29.94 ? 156 GLY A CA 1 ATOM 1192 C C . GLY A 1 148 ? 152.254 42.543 -36.996 1.00 28.05 ? 156 GLY A C 1 ATOM 1193 O O . GLY A 1 148 ? 151.032 42.626 -36.951 1.00 28.09 ? 156 GLY A O 1 ATOM 1194 N N . GLN A 1 149 ? 153.061 43.578 -36.770 1.00 25.78 ? 157 GLN A N 1 ATOM 1195 C CA . GLN A 1 149 ? 152.535 44.896 -36.414 1.00 24.49 ? 157 GLN A CA 1 ATOM 1196 C C . GLN A 1 149 ? 152.585 45.933 -37.539 1.00 21.92 ? 157 GLN A C 1 ATOM 1197 O O . GLN A 1 149 ? 152.020 47.016 -37.426 1.00 21.28 ? 157 GLN A O 1 ATOM 1198 C CB . GLN A 1 149 ? 153.286 45.425 -35.192 1.00 24.15 ? 157 GLN A CB 1 ATOM 1199 C CG . GLN A 1 149 ? 153.397 44.403 -34.089 1.00 25.37 ? 157 GLN A CG 1 ATOM 1200 C CD . GLN A 1 149 ? 154.316 44.857 -32.984 1.00 27.92 ? 157 GLN A CD 1 ATOM 1201 O OE1 . GLN A 1 149 ? 153.981 45.749 -32.211 1.00 29.04 ? 157 GLN A OE1 1 ATOM 1202 N NE2 . GLN A 1 149 ? 155.496 44.251 -32.911 1.00 29.96 ? 157 GLN A NE2 1 ATOM 1203 N N . THR A 1 150 ? 153.273 45.589 -38.617 1.00 20.87 ? 158 THR A N 1 ATOM 1204 C CA . THR A 1 150 ? 153.420 46.456 -39.778 1.00 20.08 ? 158 THR A CA 1 ATOM 1205 C C . THR A 1 150 ? 153.878 45.554 -40.919 1.00 19.85 ? 158 THR A C 1 ATOM 1206 O O . THR A 1 150 ? 154.615 44.582 -40.707 1.00 19.67 ? 158 THR A O 1 ATOM 1207 C CB . THR A 1 150 ? 154.508 47.553 -39.555 1.00 18.39 ? 158 THR A CB 1 ATOM 1208 O OG1 . THR A 1 150 ? 154.085 48.473 -38.533 1.00 17.26 ? 158 THR A OG1 1 ATOM 1209 C CG2 . THR A 1 150 ? 154.775 48.306 -40.857 1.00 14.90 ? 158 THR A CG2 1 ATOM 1210 N N . VAL A 1 151 ? 153.441 45.864 -42.128 1.00 19.19 ? 159 VAL A N 1 ATOM 1211 C CA . VAL A 1 151 ? 153.844 45.065 -43.272 1.00 20.27 ? 159 VAL A CA 1 ATOM 1212 C C . VAL A 1 151 ? 154.803 45.845 -44.167 1.00 20.01 ? 159 VAL A C 1 ATOM 1213 O O . VAL A 1 151 ? 154.626 47.049 -44.393 1.00 20.08 ? 159 VAL A O 1 ATOM 1214 C CB . VAL A 1 151 ? 152.612 44.629 -44.113 1.00 20.47 ? 159 VAL A CB 1 ATOM 1215 C CG1 . VAL A 1 151 ? 153.072 43.980 -45.415 1.00 20.13 ? 159 VAL A CG1 1 ATOM 1216 C CG2 . VAL A 1 151 ? 151.750 43.648 -43.317 1.00 18.41 ? 159 VAL A CG2 1 ATOM 1217 N N . LEU A 1 152 ? 155.839 45.167 -44.649 1.00 18.80 ? 160 LEU A N 1 ATOM 1218 C CA . LEU A 1 152 ? 156.787 45.794 -45.560 1.00 18.18 ? 160 LEU A CA 1 ATOM 1219 C C . LEU A 1 152 ? 156.433 45.170 -46.907 1.00 18.97 ? 160 LEU A C 1 ATOM 1220 O O . LEU A 1 152 ? 156.680 43.982 -47.133 1.00 18.46 ? 160 LEU A O 1 ATOM 1221 C CB . LEU A 1 152 ? 158.233 45.481 -45.151 1.00 15.80 ? 160 LEU A CB 1 ATOM 1222 C CG . LEU A 1 152 ? 158.637 45.923 -43.731 1.00 13.65 ? 160 LEU A CG 1 ATOM 1223 C CD1 . LEU A 1 152 ? 160.125 45.716 -43.537 1.00 11.93 ? 160 LEU A CD1 1 ATOM 1224 C CD2 . LEU A 1 152 ? 158.276 47.384 -43.492 1.00 10.03 ? 160 LEU A CD2 1 ATOM 1225 N N . PHE A 1 153 ? 155.813 45.973 -47.776 1.00 19.88 ? 161 PHE A N 1 ATOM 1226 C CA . PHE A 1 153 ? 155.357 45.515 -49.083 1.00 20.66 ? 161 PHE A CA 1 ATOM 1227 C C . PHE A 1 153 ? 156.371 45.835 -50.152 1.00 21.41 ? 161 PHE A C 1 ATOM 1228 O O . PHE A 1 153 ? 156.642 46.993 -50.461 1.00 21.33 ? 161 PHE A O 1 ATOM 1229 C CB . PHE A 1 153 ? 154.007 46.137 -49.415 1.00 20.42 ? 161 PHE A CB 1 ATOM 1230 C CG . PHE A 1 153 ? 153.274 45.409 -50.483 1.00 22.21 ? 161 PHE A CG 1 ATOM 1231 C CD1 . PHE A 1 153 ? 153.441 45.752 -51.824 1.00 21.39 ? 161 PHE A CD1 1 ATOM 1232 C CD2 . PHE A 1 153 ? 152.445 44.340 -50.156 1.00 22.66 ? 161 PHE A CD2 1 ATOM 1233 C CE1 . PHE A 1 153 ? 152.793 45.037 -52.830 1.00 22.04 ? 161 PHE A CE1 1 ATOM 1234 C CE2 . PHE A 1 153 ? 151.787 43.612 -51.157 1.00 24.32 ? 161 PHE A CE2 1 ATOM 1235 C CZ . PHE A 1 153 ? 151.963 43.966 -52.496 1.00 23.12 ? 161 PHE A CZ 1 ATOM 1236 N N . VAL A 1 154 ? 156.889 44.775 -50.749 1.00 22.59 ? 162 VAL A N 1 ATOM 1237 C CA . VAL A 1 154 ? 157.958 44.872 -51.715 1.00 22.40 ? 162 VAL A CA 1 ATOM 1238 C C . VAL A 1 154 ? 157.628 45.061 -53.205 1.00 22.97 ? 162 VAL A C 1 ATOM 1239 O O . VAL A 1 154 ? 158.489 44.855 -54.068 1.00 23.46 ? 162 VAL A O 1 ATOM 1240 C CB . VAL A 1 154 ? 158.896 43.650 -51.468 1.00 22.39 ? 162 VAL A CB 1 ATOM 1241 C CG1 . VAL A 1 154 ? 158.489 42.463 -52.327 1.00 21.71 ? 162 VAL A CG1 1 ATOM 1242 C CG2 . VAL A 1 154 ? 160.324 44.057 -51.645 1.00 25.09 ? 162 VAL A CG2 1 ATOM 1243 N N . GLY A 1 155 ? 156.399 45.466 -53.517 1.00 23.02 ? 163 GLY A N 1 ATOM 1244 C CA . GLY A 1 155 ? 156.059 45.703 -54.916 1.00 22.73 ? 163 GLY A CA 1 ATOM 1245 C C . GLY A 1 155 ? 155.012 44.829 -55.597 1.00 22.24 ? 163 GLY A C 1 ATOM 1246 O O . GLY A 1 155 ? 154.789 43.684 -55.201 1.00 23.42 ? 163 GLY A O 1 ATOM 1247 N N . ASP A 1 156 ? 154.396 45.378 -56.647 1.00 20.43 ? 164 ASP A N 1 ATOM 1248 C CA . ASP A 1 156 ? 153.349 44.712 -57.424 1.00 19.24 ? 164 ASP A CA 1 ATOM 1249 C C . ASP A 1 156 ? 152.129 44.506 -56.534 1.00 19.70 ? 164 ASP A C 1 ATOM 1250 O O . ASP A 1 156 ? 151.991 43.475 -55.867 1.00 19.04 ? 164 ASP A O 1 ATOM 1251 C CB . ASP A 1 156 ? 153.856 43.378 -57.991 1.00 19.62 ? 164 ASP A CB 1 ATOM 1252 C CG . ASP A 1 156 ? 154.859 43.567 -59.126 1.00 20.48 ? 164 ASP A CG 1 ATOM 1253 O OD1 . ASP A 1 156 ? 155.070 44.723 -59.560 1.00 19.01 ? 164 ASP A OD1 1 ATOM 1254 O OD2 . ASP A 1 156 ? 155.432 42.559 -59.591 1.00 21.39 ? 164 ASP A OD2 1 ATOM 1255 N N . LEU A 1 157 ? 151.246 45.501 -56.528 1.00 18.66 ? 165 LEU A N 1 ATOM 1256 C CA . LEU A 1 157 ? 150.062 45.447 -55.691 1.00 18.62 ? 165 LEU A CA 1 ATOM 1257 C C . LEU A 1 157 ? 148.864 44.706 -56.274 1.00 19.52 ? 165 LEU A C 1 ATOM 1258 O O . LEU A 1 157 ? 148.620 43.548 -55.930 1.00 20.52 ? 165 LEU A O 1 ATOM 1259 C CB . LEU A 1 157 ? 149.628 46.865 -55.283 1.00 16.76 ? 165 LEU A CB 1 ATOM 1260 C CG . LEU A 1 157 ? 150.552 47.618 -54.322 1.00 14.52 ? 165 LEU A CG 1 ATOM 1261 C CD1 . LEU A 1 157 ? 151.898 47.831 -54.988 1.00 14.33 ? 165 LEU A CD1 1 ATOM 1262 C CD2 . LEU A 1 157 ? 149.934 48.951 -53.929 1.00 12.18 ? 165 LEU A CD2 1 ATOM 1263 N N . SER A 1 158 ? 148.137 45.372 -57.168 1.00 18.73 ? 166 SER A N 1 ATOM 1264 C CA . SER A 1 158 ? 146.917 44.829 -57.760 1.00 17.67 ? 166 SER A CA 1 ATOM 1265 C C . SER A 1 158 ? 147.022 43.988 -59.021 1.00 18.84 ? 166 SER A C 1 ATOM 1266 O O . SER A 1 158 ? 146.215 43.085 -59.224 1.00 19.73 ? 166 SER A O 1 ATOM 1267 C CB . SER A 1 158 ? 145.957 45.978 -58.051 1.00 17.83 ? 166 SER A CB 1 ATOM 1268 O OG . SER A 1 158 ? 146.440 46.757 -59.135 1.00 17.20 ? 166 SER A OG 1 ATOM 1269 N N . TYR A 1 159 ? 147.991 44.293 -59.875 1.00 18.86 ? 167 TYR A N 1 ATOM 1270 C CA . TYR A 1 159 ? 148.149 43.587 -61.146 1.00 20.49 ? 167 TYR A CA 1 ATOM 1271 C C . TYR A 1 159 ? 146.987 43.950 -62.071 1.00 20.98 ? 167 TYR A C 1 ATOM 1272 O O . TYR A 1 159 ? 146.638 43.200 -62.983 1.00 21.94 ? 167 TYR A O 1 ATOM 1273 C CB . TYR A 1 159 ? 148.213 42.058 -60.955 1.00 18.94 ? 167 TYR A CB 1 ATOM 1274 C CG . TYR A 1 159 ? 149.561 41.560 -60.472 1.00 20.16 ? 167 TYR A CG 1 ATOM 1275 C CD1 . TYR A 1 159 ? 149.927 41.659 -59.125 1.00 20.66 ? 167 TYR A CD1 1 ATOM 1276 C CD2 . TYR A 1 159 ? 150.499 41.053 -61.370 1.00 19.54 ? 167 TYR A CD2 1 ATOM 1277 C CE1 . TYR A 1 159 ? 151.196 41.271 -58.687 1.00 17.92 ? 167 TYR A CE1 1 ATOM 1278 C CE2 . TYR A 1 159 ? 151.768 40.664 -60.944 1.00 19.20 ? 167 TYR A CE2 1 ATOM 1279 C CZ . TYR A 1 159 ? 152.109 40.778 -59.602 1.00 18.45 ? 167 TYR A CZ 1 ATOM 1280 O OH . TYR A 1 159 ? 153.366 40.413 -59.178 1.00 18.37 ? 167 TYR A OH 1 ATOM 1281 N N . ALA A 1 160 ? 146.396 45.116 -61.836 1.00 21.48 ? 168 ALA A N 1 ATOM 1282 C CA . ALA A 1 160 ? 145.280 45.575 -62.653 1.00 20.86 ? 168 ALA A CA 1 ATOM 1283 C C . ALA A 1 160 ? 145.711 45.824 -64.090 1.00 20.29 ? 168 ALA A C 1 ATOM 1284 O O . ALA A 1 160 ? 144.881 45.857 -64.995 1.00 20.30 ? 168 ALA A O 1 ATOM 1285 C CB . ALA A 1 160 ? 144.688 46.851 -62.061 1.00 21.34 ? 168 ALA A CB 1 ATOM 1286 N N . ASP A 1 161 ? 147.011 45.989 -64.303 1.00 21.60 ? 169 ASP A N 1 ATOM 1287 C CA . ASP A 1 161 ? 147.526 46.256 -65.642 1.00 22.94 ? 169 ASP A CA 1 ATOM 1288 C C . ASP A 1 161 ? 147.472 45.031 -66.539 1.00 23.59 ? 169 ASP A C 1 ATOM 1289 O O . ASP A 1 161 ? 147.852 45.097 -67.707 1.00 23.00 ? 169 ASP A O 1 ATOM 1290 C CB . ASP A 1 161 ? 148.961 46.795 -65.566 1.00 22.28 ? 169 ASP A CB 1 ATOM 1291 C CG . ASP A 1 161 ? 149.935 45.799 -64.955 1.00 23.98 ? 169 ASP A CG 1 ATOM 1292 O OD1 . ASP A 1 161 ? 149.512 44.995 -64.096 1.00 25.81 ? 169 ASP A OD1 1 ATOM 1293 O OD2 . ASP A 1 161 ? 151.130 45.827 -65.323 1.00 22.74 ? 169 ASP A OD2 1 ATOM 1294 N N . ARG A 1 162 ? 146.998 43.909 -66.000 1.00 25.74 ? 170 ARG A N 1 ATOM 1295 C CA . ARG A 1 162 ? 146.891 42.693 -66.802 1.00 28.28 ? 170 ARG A CA 1 ATOM 1296 C C . ARG A 1 162 ? 145.548 42.672 -67.513 1.00 28.81 ? 170 ARG A C 1 ATOM 1297 O O . ARG A 1 162 ? 145.356 41.940 -68.484 1.00 29.19 ? 170 ARG A O 1 ATOM 1298 C CB . ARG A 1 162 ? 147.029 41.444 -65.936 1.00 29.63 ? 170 ARG A CB 1 ATOM 1299 C CG . ARG A 1 162 ? 148.316 41.390 -65.162 1.00 35.07 ? 170 ARG A CG 1 ATOM 1300 C CD . ARG A 1 162 ? 148.577 40.001 -64.609 1.00 39.97 ? 170 ARG A CD 1 ATOM 1301 N NE . ARG A 1 162 ? 149.083 39.090 -65.633 1.00 43.37 ? 170 ARG A NE 1 ATOM 1302 C CZ . ARG A 1 162 ? 148.372 38.114 -66.191 1.00 43.90 ? 170 ARG A CZ 1 ATOM 1303 N NH1 . ARG A 1 162 ? 147.109 37.911 -65.823 1.00 43.02 ? 170 ARG A NH1 1 ATOM 1304 N NH2 . ARG A 1 162 ? 148.930 37.343 -67.120 1.00 43.75 ? 170 ARG A NH2 1 ATOM 1305 N N . TYR A 1 163 ? 144.613 43.478 -67.026 1.00 29.08 ? 171 TYR A N 1 ATOM 1306 C CA . TYR A 1 163 ? 143.302 43.541 -67.642 1.00 29.53 ? 171 TYR A CA 1 ATOM 1307 C C . TYR A 1 163 ? 143.311 44.535 -68.802 1.00 29.35 ? 171 TYR A C 1 ATOM 1308 O O . TYR A 1 163 ? 144.199 45.382 -68.901 1.00 29.23 ? 171 TYR A O 1 ATOM 1309 C CB . TYR A 1 163 ? 142.256 43.945 -66.603 1.00 30.38 ? 171 TYR A CB 1 ATOM 1310 C CG . TYR A 1 163 ? 142.055 42.900 -65.532 1.00 33.44 ? 171 TYR A CG 1 ATOM 1311 C CD1 . TYR A 1 163 ? 142.964 42.763 -64.484 1.00 34.44 ? 171 TYR A CD1 1 ATOM 1312 C CD2 . TYR A 1 163 ? 140.969 42.023 -65.582 1.00 34.58 ? 171 TYR A CD2 1 ATOM 1313 C CE1 . TYR A 1 163 ? 142.799 41.776 -63.510 1.00 34.92 ? 171 TYR A CE1 1 ATOM 1314 C CE2 . TYR A 1 163 ? 140.795 41.033 -64.615 1.00 35.32 ? 171 TYR A CE2 1 ATOM 1315 C CZ . TYR A 1 163 ? 141.712 40.916 -63.583 1.00 35.43 ? 171 TYR A CZ 1 ATOM 1316 O OH . TYR A 1 163 ? 141.537 39.944 -62.627 1.00 36.11 ? 171 TYR A OH 1 ATOM 1317 N N . PRO A 1 164 ? 142.337 44.425 -69.717 1.00 29.45 ? 172 PRO A N 1 ATOM 1318 C CA . PRO A 1 164 ? 142.285 45.353 -70.853 1.00 28.32 ? 172 PRO A CA 1 ATOM 1319 C C . PRO A 1 164 ? 142.158 46.809 -70.386 1.00 26.88 ? 172 PRO A C 1 ATOM 1320 O O . PRO A 1 164 ? 141.303 47.137 -69.565 1.00 25.36 ? 172 PRO A O 1 ATOM 1321 C CB . PRO A 1 164 ? 141.062 44.869 -71.637 1.00 29.10 ? 172 PRO A CB 1 ATOM 1322 C CG . PRO A 1 164 ? 140.213 44.170 -70.582 1.00 29.33 ? 172 PRO A CG 1 ATOM 1323 C CD . PRO A 1 164 ? 141.249 43.434 -69.785 1.00 28.49 ? 172 PRO A CD 1 ATOM 1324 N N . ASN A 1 165 ? 143.020 47.674 -70.914 1.00 26.77 ? 173 ASN A N 1 ATOM 1325 C CA . ASN A 1 165 ? 143.016 49.084 -70.543 1.00 27.04 ? 173 ASN A CA 1 ATOM 1326 C C . ASN A 1 165 ? 143.338 49.202 -69.053 1.00 25.77 ? 173 ASN A C 1 ATOM 1327 O O . ASN A 1 165 ? 142.935 50.162 -68.401 1.00 25.41 ? 173 ASN A O 1 ATOM 1328 C CB . ASN A 1 165 ? 141.640 49.699 -70.809 1.00 30.82 ? 173 ASN A CB 1 ATOM 1329 C CG . ASN A 1 165 ? 141.254 49.682 -72.280 1.00 32.79 ? 173 ASN A CG 1 ATOM 1330 O OD1 . ASN A 1 165 ? 140.066 49.692 -72.610 1.00 36.05 ? 173 ASN A OD1 1 ATOM 1331 N ND2 . ASN A 1 165 ? 142.248 49.677 -73.169 1.00 32.00 ? 173 ASN A ND2 1 ATOM 1332 N N . HIS A 1 166 ? 144.064 48.219 -68.527 1.00 24.21 ? 174 HIS A N 1 ATOM 1333 C CA . HIS A 1 166 ? 144.443 48.184 -67.111 1.00 23.94 ? 174 HIS A CA 1 ATOM 1334 C C . HIS A 1 166 ? 143.236 48.410 -66.220 1.00 22.80 ? 174 HIS A C 1 ATOM 1335 O O . HIS A 1 166 ? 143.378 48.989 -65.145 1.00 23.03 ? 174 HIS A O 1 ATOM 1336 C CB . HIS A 1 166 ? 145.478 49.270 -66.756 1.00 24.77 ? 174 HIS A CB 1 ATOM 1337 C CG . HIS A 1 166 ? 146.729 49.236 -67.581 1.00 25.82 ? 174 HIS A CG 1 ATOM 1338 N ND1 . HIS A 1 166 ? 147.902 49.831 -67.169 1.00 26.23 ? 174 HIS A ND1 1 ATOM 1339 C CD2 . HIS A 1 166 ? 146.974 48.729 -68.814 1.00 25.62 ? 174 HIS A CD2 1 ATOM 1340 C CE1 . HIS A 1 166 ? 148.817 49.692 -68.115 1.00 27.53 ? 174 HIS A CE1 1 ATOM 1341 N NE2 . HIS A 1 166 ? 148.280 49.029 -69.123 1.00 26.72 ? 174 HIS A NE2 1 ATOM 1342 N N . ASP A 1 167 ? 142.064 47.969 -66.669 1.00 22.05 ? 175 ASP A N 1 ATOM 1343 C CA . ASP A 1 167 ? 140.815 48.129 -65.919 1.00 20.68 ? 175 ASP A CA 1 ATOM 1344 C C . ASP A 1 167 ? 141.053 48.563 -64.480 1.00 20.30 ? 175 ASP A C 1 ATOM 1345 O O . ASP A 1 167 ? 141.209 47.716 -63.596 1.00 19.38 ? 175 ASP A O 1 ATOM 1346 C CB . ASP A 1 167 ? 140.039 46.815 -65.902 1.00 21.99 ? 175 ASP A CB 1 ATOM 1347 C CG . ASP A 1 167 ? 138.563 47.020 -65.625 1.00 23.34 ? 175 ASP A CG 1 ATOM 1348 O OD1 . ASP A 1 167 ? 138.221 47.962 -64.882 1.00 25.72 ? 175 ASP A OD1 1 ATOM 1349 O OD2 . ASP A 1 167 ? 137.741 46.238 -66.143 1.00 25.25 ? 175 ASP A OD2 1 ATOM 1350 N N . ASN A 1 168 ? 141.079 49.872 -64.237 1.00 20.16 ? 176 ASN A N 1 ATOM 1351 C CA . ASN A 1 168 ? 141.320 50.372 -62.886 1.00 20.47 ? 176 ASN A CA 1 ATOM 1352 C C . ASN A 1 168 ? 140.297 49.915 -61.851 1.00 20.95 ? 176 ASN A C 1 ATOM 1353 O O . ASN A 1 168 ? 140.453 50.189 -60.654 1.00 20.71 ? 176 ASN A O 1 ATOM 1354 C CB . ASN A 1 168 ? 141.426 51.900 -62.874 1.00 20.61 ? 176 ASN A CB 1 ATOM 1355 C CG . ASN A 1 168 ? 142.849 52.388 -63.101 1.00 21.53 ? 176 ASN A CG 1 ATOM 1356 O OD1 . ASN A 1 168 ? 143.274 53.387 -62.517 1.00 22.09 ? 176 ASN A OD1 1 ATOM 1357 N ND2 . ASN A 1 168 ? 143.590 51.687 -63.953 1.00 21.38 ? 176 ASN A ND2 1 ATOM 1358 N N . VAL A 1 169 ? 139.249 49.229 -62.297 1.00 19.85 ? 177 VAL A N 1 ATOM 1359 C CA . VAL A 1 169 ? 138.257 48.724 -61.364 1.00 20.17 ? 177 VAL A CA 1 ATOM 1360 C C . VAL A 1 169 ? 138.998 47.713 -60.490 1.00 22.04 ? 177 VAL A C 1 ATOM 1361 O O . VAL A 1 169 ? 138.677 47.528 -59.311 1.00 23.08 ? 177 VAL A O 1 ATOM 1362 C CB . VAL A 1 169 ? 137.099 48.015 -62.100 1.00 20.14 ? 177 VAL A CB 1 ATOM 1363 C CG1 . VAL A 1 169 ? 136.153 47.379 -61.102 1.00 19.73 ? 177 VAL A CG1 1 ATOM 1364 C CG2 . VAL A 1 169 ? 136.342 49.018 -62.954 1.00 21.11 ? 177 VAL A CG2 1 ATOM 1365 N N . ARG A 1 170 ? 140.007 47.072 -61.074 1.00 22.34 ? 178 ARG A N 1 ATOM 1366 C CA . ARG A 1 170 ? 140.805 46.090 -60.361 1.00 22.18 ? 178 ARG A CA 1 ATOM 1367 C C . ARG A 1 170 ? 141.705 46.710 -59.288 1.00 22.74 ? 178 ARG A C 1 ATOM 1368 O O . ARG A 1 170 ? 142.277 45.994 -58.468 1.00 23.42 ? 178 ARG A O 1 ATOM 1369 C CB . ARG A 1 170 ? 141.612 45.262 -61.362 1.00 23.90 ? 178 ARG A CB 1 ATOM 1370 C CG . ARG A 1 170 ? 140.783 44.148 -62.022 1.00 25.70 ? 178 ARG A CG 1 ATOM 1371 C CD . ARG A 1 170 ? 140.360 43.098 -60.985 1.00 27.53 ? 178 ARG A CD 1 ATOM 1372 N NE . ARG A 1 170 ? 139.465 42.073 -61.523 1.00 29.68 ? 178 ARG A NE 1 ATOM 1373 C CZ . ARG A 1 170 ? 139.099 40.977 -60.860 1.00 30.48 ? 178 ARG A CZ 1 ATOM 1374 N NH1 . ARG A 1 170 ? 139.553 40.756 -59.632 1.00 28.68 ? 178 ARG A NH1 1 ATOM 1375 N NH2 . ARG A 1 170 ? 138.274 40.099 -61.423 1.00 31.17 ? 178 ARG A NH2 1 ATOM 1376 N N . TRP A 1 171 ? 141.837 48.036 -59.294 1.00 22.26 ? 179 TRP A N 1 ATOM 1377 C CA . TRP A 1 171 ? 142.610 48.721 -58.255 1.00 22.25 ? 179 TRP A CA 1 ATOM 1378 C C . TRP A 1 171 ? 141.654 48.878 -57.082 1.00 22.77 ? 179 TRP A C 1 ATOM 1379 O O . TRP A 1 171 ? 142.047 48.751 -55.920 1.00 23.76 ? 179 TRP A O 1 ATOM 1380 C CB . TRP A 1 171 ? 143.070 50.118 -58.697 1.00 21.41 ? 179 TRP A CB 1 ATOM 1381 C CG . TRP A 1 171 ? 144.468 50.151 -59.243 1.00 21.09 ? 179 TRP A CG 1 ATOM 1382 C CD1 . TRP A 1 171 ? 144.843 50.370 -60.543 1.00 20.65 ? 179 TRP A CD1 1 ATOM 1383 C CD2 . TRP A 1 171 ? 145.679 49.922 -58.509 1.00 20.11 ? 179 TRP A CD2 1 ATOM 1384 N NE1 . TRP A 1 171 ? 146.214 50.285 -60.659 1.00 20.15 ? 179 TRP A NE1 1 ATOM 1385 C CE2 . TRP A 1 171 ? 146.749 50.007 -59.431 1.00 20.28 ? 179 TRP A CE2 1 ATOM 1386 C CE3 . TRP A 1 171 ? 145.960 49.642 -57.168 1.00 20.23 ? 179 TRP A CE3 1 ATOM 1387 C CZ2 . TRP A 1 171 ? 148.087 49.833 -59.042 1.00 19.75 ? 179 TRP A CZ2 1 ATOM 1388 C CZ3 . TRP A 1 171 ? 147.294 49.469 -56.784 1.00 20.12 ? 179 TRP A CZ3 1 ATOM 1389 C CH2 . TRP A 1 171 ? 148.337 49.562 -57.721 1.00 18.78 ? 179 TRP A CH2 1 ATOM 1390 N N . ASP A 1 172 ? 140.389 49.146 -57.404 1.00 23.40 ? 180 ASP A N 1 ATOM 1391 C CA . ASP A 1 172 ? 139.350 49.322 -56.391 1.00 24.06 ? 180 ASP A CA 1 ATOM 1392 C C . ASP A 1 172 ? 139.071 48.027 -55.635 1.00 24.44 ? 180 ASP A C 1 ATOM 1393 O O . ASP A 1 172 ? 138.978 48.039 -54.408 1.00 24.95 ? 180 ASP A O 1 ATOM 1394 C CB . ASP A 1 172 ? 138.038 49.825 -57.019 1.00 23.89 ? 180 ASP A CB 1 ATOM 1395 C CG . ASP A 1 172 ? 138.174 51.199 -57.655 1.00 23.48 ? 180 ASP A CG 1 ATOM 1396 O OD1 . ASP A 1 172 ? 138.711 52.108 -56.988 1.00 23.19 ? 180 ASP A OD1 1 ATOM 1397 O OD2 . ASP A 1 172 ? 137.736 51.370 -58.818 1.00 20.65 ? 180 ASP A OD2 1 ATOM 1398 N N . THR A 1 173 ? 138.930 46.915 -56.357 1.00 23.79 ? 181 THR A N 1 ATOM 1399 C CA . THR A 1 173 ? 138.665 45.635 -55.700 1.00 23.16 ? 181 THR A CA 1 ATOM 1400 C C . THR A 1 173 ? 139.815 45.314 -54.751 1.00 22.72 ? 181 THR A C 1 ATOM 1401 O O . THR A 1 173 ? 139.596 44.897 -53.609 1.00 22.99 ? 181 THR A O 1 ATOM 1402 C CB . THR A 1 173 ? 138.488 44.481 -56.724 1.00 24.52 ? 181 THR A CB 1 ATOM 1403 O OG1 . THR A 1 173 ? 139.607 44.451 -57.622 1.00 24.09 ? 181 THR A OG1 1 ATOM 1404 C CG2 . THR A 1 173 ? 137.191 44.668 -57.522 1.00 24.20 ? 181 THR A CG2 1 ATOM 1405 N N . TRP A 1 174 ? 141.040 45.535 -55.220 1.00 22.83 ? 182 TRP A N 1 ATOM 1406 C CA . TRP A 1 174 ? 142.231 45.281 -54.409 1.00 22.16 ? 182 TRP A CA 1 ATOM 1407 C C . TRP A 1 174 ? 142.214 46.161 -53.164 1.00 21.42 ? 182 TRP A C 1 ATOM 1408 O O . TRP A 1 174 ? 142.679 45.760 -52.098 1.00 21.33 ? 182 TRP A O 1 ATOM 1409 C CB . TRP A 1 174 ? 143.505 45.572 -55.206 1.00 22.18 ? 182 TRP A CB 1 ATOM 1410 C CG . TRP A 1 174 ? 144.729 44.920 -54.623 1.00 21.62 ? 182 TRP A CG 1 ATOM 1411 C CD1 . TRP A 1 174 ? 145.138 43.627 -54.811 1.00 21.62 ? 182 TRP A CD1 1 ATOM 1412 C CD2 . TRP A 1 174 ? 145.701 45.526 -53.756 1.00 20.68 ? 182 TRP A CD2 1 ATOM 1413 N NE1 . TRP A 1 174 ? 146.305 43.392 -54.119 1.00 21.28 ? 182 TRP A NE1 1 ATOM 1414 C CE2 . TRP A 1 174 ? 146.672 44.539 -53.463 1.00 20.90 ? 182 TRP A CE2 1 ATOM 1415 C CE3 . TRP A 1 174 ? 145.847 46.805 -53.199 1.00 19.78 ? 182 TRP A CE3 1 ATOM 1416 C CZ2 . TRP A 1 174 ? 147.775 44.792 -52.639 1.00 20.28 ? 182 TRP A CZ2 1 ATOM 1417 C CZ3 . TRP A 1 174 ? 146.944 47.058 -52.379 1.00 19.43 ? 182 TRP A CZ3 1 ATOM 1418 C CH2 . TRP A 1 174 ? 147.894 46.053 -52.108 1.00 21.18 ? 182 TRP A CH2 1 ATOM 1419 N N . GLY A 1 175 ? 141.675 47.366 -53.303 1.00 20.07 ? 183 GLY A N 1 ATOM 1420 C CA . GLY A 1 175 ? 141.605 48.263 -52.167 1.00 21.06 ? 183 GLY A CA 1 ATOM 1421 C C . GLY A 1 175 ? 140.664 47.729 -51.103 1.00 22.49 ? 183 GLY A C 1 ATOM 1422 O O . GLY A 1 175 ? 140.951 47.815 -49.906 1.00 21.62 ? 183 GLY A O 1 ATOM 1423 N N . ARG A 1 176 ? 139.537 47.171 -51.536 1.00 23.37 ? 184 ARG A N 1 ATOM 1424 C CA . ARG A 1 176 ? 138.556 46.618 -50.608 1.00 24.48 ? 184 ARG A CA 1 ATOM 1425 C C . ARG A 1 176 ? 139.060 45.306 -50.020 1.00 24.80 ? 184 ARG A C 1 ATOM 1426 O O . ARG A 1 176 ? 138.864 45.019 -48.834 1.00 24.83 ? 184 ARG A O 1 ATOM 1427 C CB . ARG A 1 176 ? 137.226 46.373 -51.321 1.00 24.56 ? 184 ARG A CB 1 ATOM 1428 C CG . ARG A 1 176 ? 136.595 47.624 -51.904 1.00 25.75 ? 184 ARG A CG 1 ATOM 1429 C CD . ARG A 1 176 ? 135.224 47.324 -52.485 1.00 26.54 ? 184 ARG A CD 1 ATOM 1430 N NE . ARG A 1 176 ? 134.996 48.082 -53.707 1.00 27.01 ? 184 ARG A NE 1 ATOM 1431 C CZ . ARG A 1 176 ? 134.647 47.526 -54.858 1.00 27.42 ? 184 ARG A CZ 1 ATOM 1432 N NH1 . ARG A 1 176 ? 134.486 46.215 -54.927 1.00 26.88 ? 184 ARG A NH1 1 ATOM 1433 N NH2 . ARG A 1 176 ? 134.473 48.276 -55.939 1.00 31.80 ? 184 ARG A NH2 1 ATOM 1434 N N . PHE A 1 177 ? 139.708 44.515 -50.868 1.00 23.65 ? 185 PHE A N 1 ATOM 1435 C CA . PHE A 1 177 ? 140.255 43.226 -50.474 1.00 22.62 ? 185 PHE A CA 1 ATOM 1436 C C . PHE A 1 177 ? 141.288 43.314 -49.350 1.00 23.11 ? 185 PHE A C 1 ATOM 1437 O O . PHE A 1 177 ? 141.198 42.598 -48.353 1.00 24.54 ? 185 PHE A O 1 ATOM 1438 C CB . PHE A 1 177 ? 140.869 42.555 -51.705 1.00 21.40 ? 185 PHE A CB 1 ATOM 1439 C CG . PHE A 1 177 ? 141.843 41.454 -51.390 1.00 21.18 ? 185 PHE A CG 1 ATOM 1440 C CD1 . PHE A 1 177 ? 141.513 40.442 -50.504 1.00 21.38 ? 185 PHE A CD1 1 ATOM 1441 C CD2 . PHE A 1 177 ? 143.086 41.423 -52.005 1.00 20.98 ? 185 PHE A CD2 1 ATOM 1442 C CE1 . PHE A 1 177 ? 142.405 39.410 -50.244 1.00 22.23 ? 185 PHE A CE1 1 ATOM 1443 C CE2 . PHE A 1 177 ? 143.980 40.398 -51.752 1.00 21.37 ? 185 PHE A CE2 1 ATOM 1444 C CZ . PHE A 1 177 ? 143.641 39.390 -50.868 1.00 21.67 ? 185 PHE A CZ 1 ATOM 1445 N N . THR A 1 178 ? 142.267 44.194 -49.508 1.00 22.20 ? 186 THR A N 1 ATOM 1446 C CA . THR A 1 178 ? 143.320 44.334 -48.518 1.00 20.94 ? 186 THR A CA 1 ATOM 1447 C C . THR A 1 178 ? 142.918 45.173 -47.311 1.00 22.11 ? 186 THR A C 1 ATOM 1448 O O . THR A 1 178 ? 143.592 45.141 -46.280 1.00 22.81 ? 186 THR A O 1 ATOM 1449 C CB . THR A 1 178 ? 144.598 44.946 -49.152 1.00 20.35 ? 186 THR A CB 1 ATOM 1450 O OG1 . THR A 1 178 ? 144.267 46.190 -49.781 1.00 21.33 ? 186 THR A OG1 1 ATOM 1451 C CG2 . THR A 1 178 ? 145.192 44.008 -50.196 1.00 16.84 ? 186 THR A CG2 1 ATOM 1452 N N . GLU A 1 179 ? 141.816 45.907 -47.417 1.00 21.89 ? 187 GLU A N 1 ATOM 1453 C CA . GLU A 1 179 ? 141.391 46.754 -46.306 1.00 22.39 ? 187 GLU A CA 1 ATOM 1454 C C . GLU A 1 179 ? 141.331 46.067 -44.943 1.00 23.77 ? 187 GLU A C 1 ATOM 1455 O O . GLU A 1 179 ? 141.623 46.700 -43.918 1.00 23.45 ? 187 GLU A O 1 ATOM 1456 C CB . GLU A 1 179 ? 140.026 47.392 -46.590 1.00 22.01 ? 187 GLU A CB 1 ATOM 1457 C CG . GLU A 1 179 ? 139.552 48.294 -45.454 1.00 21.84 ? 187 GLU A CG 1 ATOM 1458 C CD . GLU A 1 179 ? 138.153 48.817 -45.677 1.00 23.81 ? 187 GLU A CD 1 ATOM 1459 O OE1 . GLU A 1 179 ? 137.985 49.829 -46.394 1.00 23.00 ? 187 GLU A OE1 1 ATOM 1460 O OE2 . GLU A 1 179 ? 137.217 48.199 -45.136 1.00 24.34 ? 187 GLU A OE2 1 ATOM 1461 N N . ARG A 1 180 ? 140.953 44.788 -44.911 1.00 23.91 ? 188 ARG A N 1 ATOM 1462 C CA . ARG A 1 180 ? 140.840 44.097 -43.630 1.00 23.46 ? 188 ARG A CA 1 ATOM 1463 C C . ARG A 1 180 ? 142.143 44.120 -42.832 1.00 24.39 ? 188 ARG A C 1 ATOM 1464 O O . ARG A 1 180 ? 142.155 43.823 -41.641 1.00 25.50 ? 188 ARG A O 1 ATOM 1465 C CB . ARG A 1 180 ? 140.329 42.660 -43.837 1.00 23.48 ? 188 ARG A CB 1 ATOM 1466 C CG . ARG A 1 180 ? 141.358 41.610 -44.220 1.00 25.20 ? 188 ARG A CG 1 ATOM 1467 C CD . ARG A 1 180 ? 140.660 40.351 -44.757 1.00 26.91 ? 188 ARG A CD 1 ATOM 1468 N NE . ARG A 1 180 ? 141.522 39.165 -44.802 1.00 29.00 ? 188 ARG A NE 1 ATOM 1469 C CZ . ARG A 1 180 ? 141.515 38.261 -45.786 1.00 30.13 ? 188 ARG A CZ 1 ATOM 1470 N NH1 . ARG A 1 180 ? 140.697 38.398 -46.823 1.00 29.65 ? 188 ARG A NH1 1 ATOM 1471 N NH2 . ARG A 1 180 ? 142.322 37.209 -45.735 1.00 30.70 ? 188 ARG A NH2 1 ATOM 1472 N N . SER A 1 181 ? 143.238 44.503 -43.482 1.00 23.81 ? 189 SER A N 1 ATOM 1473 C CA . SER A 1 181 ? 144.531 44.565 -42.806 1.00 20.93 ? 189 SER A CA 1 ATOM 1474 C C . SER A 1 181 ? 145.128 45.970 -42.784 1.00 21.03 ? 189 SER A C 1 ATOM 1475 O O . SER A 1 181 ? 145.396 46.518 -41.711 1.00 20.77 ? 189 SER A O 1 ATOM 1476 C CB . SER A 1 181 ? 145.523 43.599 -43.472 1.00 20.00 ? 189 SER A CB 1 ATOM 1477 O OG . SER A 1 181 ? 146.812 43.686 -42.890 1.00 15.46 ? 189 SER A OG 1 ATOM 1478 N N . VAL A 1 182 ? 145.330 46.544 -43.970 1.00 20.56 ? 190 VAL A N 1 ATOM 1479 C CA . VAL A 1 182 ? 145.928 47.871 -44.112 1.00 20.09 ? 190 VAL A CA 1 ATOM 1480 C C . VAL A 1 182 ? 145.186 48.990 -43.395 1.00 20.01 ? 190 VAL A C 1 ATOM 1481 O O . VAL A 1 182 ? 145.730 50.076 -43.202 1.00 20.46 ? 190 VAL A O 1 ATOM 1482 C CB . VAL A 1 182 ? 146.040 48.291 -45.584 1.00 20.05 ? 190 VAL A CB 1 ATOM 1483 C CG1 . VAL A 1 182 ? 147.322 49.073 -45.792 1.00 19.69 ? 190 VAL A CG1 1 ATOM 1484 C CG2 . VAL A 1 182 ? 145.991 47.082 -46.481 1.00 22.99 ? 190 VAL A CG2 1 ATOM 1485 N N . ALA A 1 183 ? 143.941 48.741 -43.015 1.00 19.41 ? 191 ALA A N 1 ATOM 1486 C CA . ALA A 1 183 ? 143.166 49.759 -42.324 1.00 19.96 ? 191 ALA A CA 1 ATOM 1487 C C . ALA A 1 183 ? 143.494 49.735 -40.836 1.00 20.81 ? 191 ALA A C 1 ATOM 1488 O O . ALA A 1 183 ? 143.329 50.738 -40.137 1.00 21.52 ? 191 ALA A O 1 ATOM 1489 C CB . ALA A 1 183 ? 141.665 49.514 -42.535 1.00 18.82 ? 191 ALA A CB 1 ATOM 1490 N N . TYR A 1 184 ? 143.979 48.590 -40.365 1.00 21.14 ? 192 TYR A N 1 ATOM 1491 C CA . TYR A 1 184 ? 144.291 48.406 -38.955 1.00 22.07 ? 192 TYR A CA 1 ATOM 1492 C C . TYR A 1 184 ? 145.767 48.497 -38.590 1.00 24.13 ? 192 TYR A C 1 ATOM 1493 O O . TYR A 1 184 ? 146.106 48.731 -37.431 1.00 24.85 ? 192 TYR A O 1 ATOM 1494 C CB . TYR A 1 184 ? 143.713 47.072 -38.494 1.00 22.65 ? 192 TYR A CB 1 ATOM 1495 C CG . TYR A 1 184 ? 142.202 47.043 -38.547 1.00 24.96 ? 192 TYR A CG 1 ATOM 1496 C CD1 . TYR A 1 184 ? 141.438 47.658 -37.549 1.00 25.92 ? 192 TYR A CD1 1 ATOM 1497 C CD2 . TYR A 1 184 ? 141.533 46.454 -39.619 1.00 24.75 ? 192 TYR A CD2 1 ATOM 1498 C CE1 . TYR A 1 184 ? 140.053 47.693 -37.617 1.00 26.72 ? 192 TYR A CE1 1 ATOM 1499 C CE2 . TYR A 1 184 ? 140.139 46.486 -39.698 1.00 27.40 ? 192 TYR A CE2 1 ATOM 1500 C CZ . TYR A 1 184 ? 139.408 47.109 -38.692 1.00 27.64 ? 192 TYR A CZ 1 ATOM 1501 O OH . TYR A 1 184 ? 138.035 47.159 -38.762 1.00 30.70 ? 192 TYR A OH 1 ATOM 1502 N N . GLN A 1 185 ? 146.647 48.299 -39.566 1.00 24.68 ? 193 GLN A N 1 ATOM 1503 C CA . GLN A 1 185 ? 148.079 48.400 -39.314 1.00 23.34 ? 193 GLN A CA 1 ATOM 1504 C C . GLN A 1 185 ? 148.733 48.927 -40.583 1.00 24.70 ? 193 GLN A C 1 ATOM 1505 O O . GLN A 1 185 ? 148.309 48.602 -41.693 1.00 25.53 ? 193 GLN A O 1 ATOM 1506 C CB . GLN A 1 185 ? 148.667 47.038 -38.938 1.00 22.51 ? 193 GLN A CB 1 ATOM 1507 C CG . GLN A 1 185 ? 149.024 46.146 -40.114 1.00 23.29 ? 193 GLN A CG 1 ATOM 1508 C CD . GLN A 1 185 ? 149.635 44.832 -39.664 1.00 23.54 ? 193 GLN A CD 1 ATOM 1509 O OE1 . GLN A 1 185 ? 150.599 44.340 -40.254 1.00 22.75 ? 193 GLN A OE1 1 ATOM 1510 N NE2 . GLN A 1 185 ? 149.065 44.250 -38.618 1.00 22.43 ? 193 GLN A NE2 1 ATOM 1511 N N . PRO A 1 186 ? 149.776 49.751 -40.440 1.00 23.99 ? 194 PRO A N 1 ATOM 1512 C CA . PRO A 1 186 ? 150.453 50.301 -41.620 1.00 23.86 ? 194 PRO A CA 1 ATOM 1513 C C . PRO A 1 186 ? 151.154 49.283 -42.517 1.00 23.39 ? 194 PRO A C 1 ATOM 1514 O O . PRO A 1 186 ? 151.552 48.205 -42.078 1.00 24.47 ? 194 PRO A O 1 ATOM 1515 C CB . PRO A 1 186 ? 151.436 51.303 -41.015 1.00 23.12 ? 194 PRO A CB 1 ATOM 1516 C CG . PRO A 1 186 ? 151.769 50.666 -39.686 1.00 23.69 ? 194 PRO A CG 1 ATOM 1517 C CD . PRO A 1 186 ? 150.413 50.218 -39.196 1.00 22.97 ? 194 PRO A CD 1 ATOM 1518 N N . TRP A 1 187 ? 151.278 49.648 -43.787 1.00 22.76 ? 195 TRP A N 1 ATOM 1519 C CA . TRP A 1 187 ? 151.976 48.856 -44.793 1.00 21.27 ? 195 TRP A CA 1 ATOM 1520 C C . TRP A 1 187 ? 152.936 49.855 -45.420 1.00 20.28 ? 195 TRP A C 1 ATOM 1521 O O . TRP A 1 187 ? 152.535 50.972 -45.750 1.00 18.40 ? 195 TRP A O 1 ATOM 1522 C CB . TRP A 1 187 ? 151.019 48.354 -45.871 1.00 21.74 ? 195 TRP A CB 1 ATOM 1523 C CG . TRP A 1 187 ? 150.218 47.165 -45.476 1.00 22.79 ? 195 TRP A CG 1 ATOM 1524 C CD1 . TRP A 1 187 ? 149.670 46.916 -44.248 1.00 23.06 ? 195 TRP A CD1 1 ATOM 1525 C CD2 . TRP A 1 187 ? 149.821 46.078 -46.323 1.00 22.20 ? 195 TRP A CD2 1 ATOM 1526 N NE1 . TRP A 1 187 ? 148.953 45.742 -44.279 1.00 22.12 ? 195 TRP A NE1 1 ATOM 1527 C CE2 . TRP A 1 187 ? 149.026 45.207 -45.539 1.00 21.71 ? 195 TRP A CE2 1 ATOM 1528 C CE3 . TRP A 1 187 ? 150.052 45.758 -47.670 1.00 22.42 ? 195 TRP A CE3 1 ATOM 1529 C CZ2 . TRP A 1 187 ? 148.460 44.029 -46.056 1.00 19.29 ? 195 TRP A CZ2 1 ATOM 1530 C CZ3 . TRP A 1 187 ? 149.486 44.581 -48.189 1.00 21.98 ? 195 TRP A CZ3 1 ATOM 1531 C CH2 . TRP A 1 187 ? 148.699 43.735 -47.377 1.00 20.61 ? 195 TRP A CH2 1 ATOM 1532 N N . ILE A 1 188 ? 154.199 49.472 -45.572 1.00 20.00 ? 196 ILE A N 1 ATOM 1533 C CA . ILE A 1 188 ? 155.185 50.368 -46.169 1.00 18.68 ? 196 ILE A CA 1 ATOM 1534 C C . ILE A 1 188 ? 155.237 50.061 -47.652 1.00 17.47 ? 196 ILE A C 1 ATOM 1535 O O . ILE A 1 188 ? 155.621 48.963 -48.041 1.00 18.74 ? 196 ILE A O 1 ATOM 1536 C CB . ILE A 1 188 ? 156.570 50.158 -45.547 1.00 17.14 ? 196 ILE A CB 1 ATOM 1537 C CG1 . ILE A 1 188 ? 156.452 50.202 -44.023 1.00 16.73 ? 196 ILE A CG1 1 ATOM 1538 C CG2 . ILE A 1 188 ? 157.515 51.238 -46.023 1.00 16.73 ? 196 ILE A CG2 1 ATOM 1539 C CD1 . ILE A 1 188 ? 155.683 51.415 -43.504 1.00 14.68 ? 196 ILE A CD1 1 ATOM 1540 N N . TRP A 1 189 ? 154.864 51.025 -48.485 1.00 16.37 ? 197 TRP A N 1 ATOM 1541 C CA . TRP A 1 189 ? 154.839 50.776 -49.917 1.00 14.91 ? 197 TRP A CA 1 ATOM 1542 C C . TRP A 1 189 ? 156.140 50.923 -50.715 1.00 14.35 ? 197 TRP A C 1 ATOM 1543 O O . TRP A 1 189 ? 156.912 51.863 -50.536 1.00 13.87 ? 197 TRP A O 1 ATOM 1544 C CB . TRP A 1 189 ? 153.760 51.635 -50.559 1.00 15.55 ? 197 TRP A CB 1 ATOM 1545 C CG . TRP A 1 189 ? 152.425 51.517 -49.902 1.00 16.55 ? 197 TRP A CG 1 ATOM 1546 C CD1 . TRP A 1 189 ? 151.792 52.477 -49.171 1.00 17.28 ? 197 TRP A CD1 1 ATOM 1547 C CD2 . TRP A 1 189 ? 151.551 50.382 -49.921 1.00 16.91 ? 197 TRP A CD2 1 ATOM 1548 N NE1 . TRP A 1 189 ? 150.575 52.013 -48.734 1.00 18.27 ? 197 TRP A NE1 1 ATOM 1549 C CE2 . TRP A 1 189 ? 150.400 50.729 -49.180 1.00 17.79 ? 197 TRP A CE2 1 ATOM 1550 C CE3 . TRP A 1 189 ? 151.627 49.105 -50.492 1.00 18.73 ? 197 TRP A CE3 1 ATOM 1551 C CZ2 . TRP A 1 189 ? 149.326 49.842 -48.990 1.00 18.65 ? 197 TRP A CZ2 1 ATOM 1552 C CZ3 . TRP A 1 189 ? 150.554 48.217 -50.303 1.00 20.21 ? 197 TRP A CZ3 1 ATOM 1553 C CH2 . TRP A 1 189 ? 149.422 48.596 -49.558 1.00 18.36 ? 197 TRP A CH2 1 ATOM 1554 N N . THR A 1 190 ? 156.353 49.960 -51.604 1.00 13.85 ? 198 THR A N 1 ATOM 1555 C CA . THR A 1 190 ? 157.503 49.908 -52.500 1.00 14.42 ? 198 THR A CA 1 ATOM 1556 C C . THR A 1 190 ? 156.875 49.765 -53.882 1.00 14.40 ? 198 THR A C 1 ATOM 1557 O O . THR A 1 190 ? 155.959 48.959 -54.052 1.00 14.32 ? 198 THR A O 1 ATOM 1558 C CB . THR A 1 190 ? 158.356 48.661 -52.239 1.00 14.79 ? 198 THR A CB 1 ATOM 1559 O OG1 . THR A 1 190 ? 158.896 48.720 -50.918 1.00 15.04 ? 198 THR A OG1 1 ATOM 1560 C CG2 . THR A 1 190 ? 159.485 48.570 -53.238 1.00 15.40 ? 198 THR A CG2 1 ATOM 1561 N N . ALA A 1 191 ? 157.347 50.527 -54.863 1.00 12.97 ? 199 ALA A N 1 ATOM 1562 C CA . ALA A 1 191 ? 156.764 50.442 -56.198 1.00 14.00 ? 199 ALA A CA 1 ATOM 1563 C C . ALA A 1 191 ? 157.375 49.322 -57.037 1.00 14.80 ? 199 ALA A C 1 ATOM 1564 O O . ALA A 1 191 ? 158.596 49.190 -57.129 1.00 14.87 ? 199 ALA A O 1 ATOM 1565 C CB . ALA A 1 191 ? 156.910 51.779 -56.921 1.00 11.81 ? 199 ALA A CB 1 ATOM 1566 N N . GLY A 1 192 ? 156.510 48.519 -57.650 1.00 15.86 ? 200 GLY A N 1 ATOM 1567 C CA . GLY A 1 192 ? 156.958 47.415 -58.487 1.00 15.49 ? 200 GLY A CA 1 ATOM 1568 C C . GLY A 1 192 ? 156.706 47.666 -59.968 1.00 16.34 ? 200 GLY A C 1 ATOM 1569 O O . GLY A 1 192 ? 156.087 48.670 -60.337 1.00 15.69 ? 200 GLY A O 1 ATOM 1570 N N . ASN A 1 193 ? 157.170 46.758 -60.823 1.00 14.79 ? 201 ASN A N 1 ATOM 1571 C CA . ASN A 1 193 ? 157.000 46.932 -62.257 1.00 14.92 ? 201 ASN A CA 1 ATOM 1572 C C . ASN A 1 193 ? 155.550 46.981 -62.730 1.00 14.50 ? 201 ASN A C 1 ATOM 1573 O O . ASN A 1 193 ? 155.264 47.536 -63.785 1.00 12.20 ? 201 ASN A O 1 ATOM 1574 C CB . ASN A 1 193 ? 157.755 45.837 -63.020 1.00 17.97 ? 201 ASN A CB 1 ATOM 1575 C CG . ASN A 1 193 ? 157.207 44.453 -62.748 1.00 21.06 ? 201 ASN A CG 1 ATOM 1576 O OD1 . ASN A 1 193 ? 157.194 43.986 -61.603 1.00 25.19 ? 201 ASN A OD1 1 ATOM 1577 N ND2 . ASN A 1 193 ? 156.749 43.785 -63.797 1.00 20.65 ? 201 ASN A ND2 1 ATOM 1578 N N . HIS A 1 194 ? 154.630 46.408 -61.967 1.00 14.94 ? 202 HIS A N 1 ATOM 1579 C CA . HIS A 1 194 ? 153.235 46.430 -62.385 1.00 17.12 ? 202 HIS A CA 1 ATOM 1580 C C . HIS A 1 194 ? 152.562 47.730 -61.971 1.00 18.09 ? 202 HIS A C 1 ATOM 1581 O O . HIS A 1 194 ? 151.373 47.931 -62.222 1.00 17.24 ? 202 HIS A O 1 ATOM 1582 C CB . HIS A 1 194 ? 152.479 45.231 -61.813 1.00 18.08 ? 202 HIS A CB 1 ATOM 1583 C CG . HIS A 1 194 ? 152.685 43.966 -62.589 1.00 21.94 ? 202 HIS A CG 1 ATOM 1584 N ND1 . HIS A 1 194 ? 151.937 43.647 -63.703 1.00 22.28 ? 202 HIS A ND1 1 ATOM 1585 C CD2 . HIS A 1 194 ? 153.591 42.968 -62.444 1.00 22.77 ? 202 HIS A CD2 1 ATOM 1586 C CE1 . HIS A 1 194 ? 152.376 42.508 -64.212 1.00 23.06 ? 202 HIS A CE1 1 ATOM 1587 N NE2 . HIS A 1 194 ? 153.379 42.076 -63.468 1.00 24.13 ? 202 HIS A NE2 1 ATOM 1588 N N . GLU A 1 195 ? 153.332 48.613 -61.339 1.00 18.11 ? 203 GLU A N 1 ATOM 1589 C CA . GLU A 1 195 ? 152.814 49.907 -60.935 1.00 17.03 ? 203 GLU A CA 1 ATOM 1590 C C . GLU A 1 195 ? 153.228 50.966 -61.959 1.00 17.68 ? 203 GLU A C 1 ATOM 1591 O O . GLU A 1 195 ? 152.703 52.083 -61.948 1.00 17.84 ? 203 GLU A O 1 ATOM 1592 C CB . GLU A 1 195 ? 153.335 50.301 -59.553 1.00 17.70 ? 203 GLU A CB 1 ATOM 1593 C CG . GLU A 1 195 ? 152.512 49.770 -58.383 1.00 19.34 ? 203 GLU A CG 1 ATOM 1594 C CD . GLU A 1 195 ? 152.697 48.283 -58.149 1.00 19.91 ? 203 GLU A CD 1 ATOM 1595 O OE1 . GLU A 1 195 ? 153.839 47.866 -57.878 1.00 20.18 ? 203 GLU A OE1 1 ATOM 1596 O OE2 . GLU A 1 195 ? 151.704 47.528 -58.227 1.00 20.58 ? 203 GLU A OE2 1 ATOM 1597 N N . ILE A 1 196 ? 154.159 50.618 -62.848 1.00 16.29 ? 204 ILE A N 1 ATOM 1598 C CA . ILE A 1 196 ? 154.612 51.569 -63.859 1.00 17.89 ? 204 ILE A CA 1 ATOM 1599 C C . ILE A 1 196 ? 153.432 52.003 -64.726 1.00 19.27 ? 204 ILE A C 1 ATOM 1600 O O . ILE A 1 196 ? 153.169 53.191 -64.889 1.00 20.10 ? 204 ILE A O 1 ATOM 1601 C CB . ILE A 1 196 ? 155.710 50.961 -64.765 1.00 17.75 ? 204 ILE A CB 1 ATOM 1602 C CG1 . ILE A 1 196 ? 156.921 50.562 -63.918 1.00 16.15 ? 204 ILE A CG1 1 ATOM 1603 C CG2 . ILE A 1 196 ? 156.146 51.976 -65.808 1.00 15.77 ? 204 ILE A CG2 1 ATOM 1604 C CD1 . ILE A 1 196 ? 157.971 49.794 -64.688 1.00 12.65 ? 204 ILE A CD1 1 ATOM 1605 N N . GLU A 1 197 ? 152.715 51.030 -65.273 1.00 21.07 ? 205 GLU A N 1 ATOM 1606 C CA . GLU A 1 197 ? 151.553 51.287 -66.122 1.00 20.16 ? 205 GLU A CA 1 ATOM 1607 C C . GLU A 1 197 ? 151.804 52.316 -67.219 1.00 20.36 ? 205 GLU A C 1 ATOM 1608 O O . GLU A 1 197 ? 151.083 53.310 -67.344 1.00 20.04 ? 205 GLU A O 1 ATOM 1609 C CB . GLU A 1 197 ? 150.347 51.701 -65.269 1.00 19.31 ? 205 GLU A CB 1 ATOM 1610 C CG . GLU A 1 197 ? 149.910 50.610 -64.288 1.00 21.39 ? 205 GLU A CG 1 ATOM 1611 C CD . GLU A 1 197 ? 148.470 50.755 -63.825 1.00 22.43 ? 205 GLU A CD 1 ATOM 1612 O OE1 . GLU A 1 197 ? 147.571 50.656 -64.688 1.00 23.13 ? 205 GLU A OE1 1 ATOM 1613 O OE2 . GLU A 1 197 ? 148.240 50.968 -62.609 1.00 19.89 ? 205 GLU A OE2 1 ATOM 1614 N N . PHE A 1 198 ? 152.835 52.065 -68.018 1.00 19.89 ? 206 PHE A N 1 ATOM 1615 C CA . PHE A 1 198 ? 153.181 52.941 -69.128 1.00 19.29 ? 206 PHE A CA 1 ATOM 1616 C C . PHE A 1 198 ? 152.410 52.432 -70.336 1.00 20.21 ? 206 PHE A C 1 ATOM 1617 O O . PHE A 1 198 ? 152.787 51.423 -70.935 1.00 20.77 ? 206 PHE A O 1 ATOM 1618 C CB . PHE A 1 198 ? 154.676 52.859 -69.397 1.00 18.24 ? 206 PHE A CB 1 ATOM 1619 C CG . PHE A 1 198 ? 155.119 53.646 -70.584 1.00 16.59 ? 206 PHE A CG 1 ATOM 1620 C CD1 . PHE A 1 198 ? 154.898 55.025 -70.644 1.00 16.37 ? 206 PHE A CD1 1 ATOM 1621 C CD2 . PHE A 1 198 ? 155.778 53.016 -71.639 1.00 14.90 ? 206 PHE A CD2 1 ATOM 1622 C CE1 . PHE A 1 198 ? 155.332 55.777 -71.741 1.00 15.68 ? 206 PHE A CE1 1 ATOM 1623 C CE2 . PHE A 1 198 ? 156.219 53.751 -72.741 1.00 14.91 ? 206 PHE A CE2 1 ATOM 1624 C CZ . PHE A 1 198 ? 155.993 55.142 -72.791 1.00 15.45 ? 206 PHE A CZ 1 ATOM 1625 N N . ALA A 1 199 ? 151.335 53.125 -70.695 1.00 20.96 ? 207 ALA A N 1 ATOM 1626 C CA . ALA A 1 199 ? 150.504 52.686 -71.809 1.00 22.12 ? 207 ALA A CA 1 ATOM 1627 C C . ALA A 1 199 ? 150.246 53.751 -72.871 1.00 23.65 ? 207 ALA A C 1 ATOM 1628 O O . ALA A 1 199 ? 149.183 54.369 -72.898 1.00 23.82 ? 207 ALA A O 1 ATOM 1629 C CB . ALA A 1 199 ? 149.174 52.158 -71.270 1.00 22.24 ? 207 ALA A CB 1 ATOM 1630 N N . PRO A 1 200 ? 151.213 53.963 -73.777 1.00 24.68 ? 208 PRO A N 1 ATOM 1631 C CA . PRO A 1 200 ? 151.085 54.957 -74.847 1.00 25.28 ? 208 PRO A CA 1 ATOM 1632 C C . PRO A 1 200 ? 149.882 54.695 -75.753 1.00 26.24 ? 208 PRO A C 1 ATOM 1633 O O . PRO A 1 200 ? 149.227 55.629 -76.213 1.00 26.13 ? 208 PRO A O 1 ATOM 1634 C CB . PRO A 1 200 ? 152.396 54.811 -75.620 1.00 23.81 ? 208 PRO A CB 1 ATOM 1635 C CG . PRO A 1 200 ? 153.343 54.287 -74.615 1.00 24.45 ? 208 PRO A CG 1 ATOM 1636 C CD . PRO A 1 200 ? 152.523 53.292 -73.844 1.00 24.45 ? 208 PRO A CD 1 ATOM 1637 N N . GLU A 1 201 ? 149.605 53.422 -76.017 1.00 27.38 ? 209 GLU A N 1 ATOM 1638 C CA . GLU A 1 201 ? 148.497 53.062 -76.890 1.00 30.59 ? 209 GLU A CA 1 ATOM 1639 C C . GLU A 1 201 ? 147.223 53.776 -76.470 1.00 30.46 ? 209 GLU A C 1 ATOM 1640 O O . GLU A 1 201 ? 146.427 54.187 -77.314 1.00 31.69 ? 209 GLU A O 1 ATOM 1641 C CB . GLU A 1 201 ? 148.240 51.551 -76.872 1.00 33.28 ? 209 GLU A CB 1 ATOM 1642 C CG . GLU A 1 201 ? 149.435 50.698 -76.515 1.00 40.45 ? 209 GLU A CG 1 ATOM 1643 C CD . GLU A 1 201 ? 149.660 50.617 -75.013 1.00 44.42 ? 209 GLU A CD 1 ATOM 1644 O OE1 . GLU A 1 201 ? 148.714 50.229 -74.287 1.00 44.14 ? 209 GLU A OE1 1 ATOM 1645 O OE2 . GLU A 1 201 ? 150.782 50.938 -74.562 1.00 47.20 ? 209 GLU A OE2 1 ATOM 1646 N N . ILE A 1 202 ? 147.030 53.935 -75.168 1.00 27.73 ? 210 ILE A N 1 ATOM 1647 C CA . ILE A 1 202 ? 145.827 54.588 -74.692 1.00 26.60 ? 210 ILE A CA 1 ATOM 1648 C C . ILE A 1 202 ? 146.097 55.963 -74.088 1.00 26.44 ? 210 ILE A C 1 ATOM 1649 O O . ILE A 1 202 ? 145.391 56.417 -73.189 1.00 27.27 ? 210 ILE A O 1 ATOM 1650 C CB . ILE A 1 202 ? 145.109 53.682 -73.689 1.00 27.40 ? 210 ILE A CB 1 ATOM 1651 C CG1 . ILE A 1 202 ? 146.048 53.341 -72.532 1.00 27.94 ? 210 ILE A CG1 1 ATOM 1652 C CG2 . ILE A 1 202 ? 144.671 52.400 -74.392 1.00 24.47 ? 210 ILE A CG2 1 ATOM 1653 C CD1 . ILE A 1 202 ? 145.411 52.461 -71.462 1.00 28.85 ? 210 ILE A CD1 1 ATOM 1654 N N . ASN A 1 203 ? 147.132 56.616 -74.603 1.00 26.94 ? 211 ASN A N 1 ATOM 1655 C CA . ASN A 1 203 ? 147.533 57.948 -74.170 1.00 28.07 ? 211 ASN A CA 1 ATOM 1656 C C . ASN A 1 203 ? 147.753 58.099 -72.662 1.00 27.40 ? 211 ASN A C 1 ATOM 1657 O O . ASN A 1 203 ? 147.417 59.131 -72.083 1.00 27.71 ? 211 ASN A O 1 ATOM 1658 C CB . ASN A 1 203 ? 146.500 58.972 -74.650 1.00 32.72 ? 211 ASN A CB 1 ATOM 1659 C CG . ASN A 1 203 ? 147.120 60.327 -74.994 1.00 38.26 ? 211 ASN A CG 1 ATOM 1660 O OD1 . ASN A 1 203 ? 147.640 61.039 -74.129 1.00 39.08 ? 211 ASN A OD1 1 ATOM 1661 N ND2 . ASN A 1 203 ? 147.062 60.688 -76.275 1.00 43.22 ? 211 ASN A ND2 1 ATOM 1662 N N . GLU A 1 204 ? 148.298 57.067 -72.024 1.00 26.32 ? 212 GLU A N 1 ATOM 1663 C CA . GLU A 1 204 ? 148.593 57.117 -70.587 1.00 25.45 ? 212 GLU A CA 1 ATOM 1664 C C . GLU A 1 204 ? 150.100 56.956 -70.466 1.00 26.41 ? 212 GLU A C 1 ATOM 1665 O O . GLU A 1 204 ? 150.609 55.843 -70.301 1.00 26.98 ? 212 GLU A O 1 ATOM 1666 C CB . GLU A 1 204 ? 147.882 55.994 -69.845 1.00 22.92 ? 212 GLU A CB 1 ATOM 1667 C CG . GLU A 1 204 ? 146.406 56.251 -69.626 1.00 23.86 ? 212 GLU A CG 1 ATOM 1668 C CD . GLU A 1 204 ? 146.149 57.530 -68.844 1.00 24.85 ? 212 GLU A CD 1 ATOM 1669 O OE1 . GLU A 1 204 ? 146.829 57.760 -67.822 1.00 27.27 ? 212 GLU A OE1 1 ATOM 1670 O OE2 . GLU A 1 204 ? 145.262 58.309 -69.242 1.00 25.06 ? 212 GLU A OE2 1 ATOM 1671 N N . THR A 1 205 ? 150.805 58.081 -70.553 1.00 26.79 ? 213 THR A N 1 ATOM 1672 C CA . THR A 1 205 ? 152.262 58.091 -70.530 1.00 27.19 ? 213 THR A CA 1 ATOM 1673 C C . THR A 1 205 ? 152.945 58.538 -69.240 1.00 27.95 ? 213 THR A C 1 ATOM 1674 O O . THR A 1 205 ? 154.158 58.725 -69.215 1.00 29.55 ? 213 THR A O 1 ATOM 1675 C CB . THR A 1 205 ? 152.778 58.973 -71.673 1.00 26.43 ? 213 THR A CB 1 ATOM 1676 O OG1 . THR A 1 205 ? 152.246 60.295 -71.525 1.00 26.10 ? 213 THR A OG1 1 ATOM 1677 C CG2 . THR A 1 205 ? 152.330 58.419 -73.014 1.00 25.01 ? 213 THR A CG2 1 ATOM 1678 N N . GLU A 1 206 ? 152.181 58.710 -68.174 1.00 27.89 ? 214 GLU A N 1 ATOM 1679 C CA . GLU A 1 206 ? 152.744 59.144 -66.905 1.00 28.34 ? 214 GLU A CA 1 ATOM 1680 C C . GLU A 1 206 ? 152.976 57.905 -66.038 1.00 26.74 ? 214 GLU A C 1 ATOM 1681 O O . GLU A 1 206 ? 152.031 57.291 -65.550 1.00 26.52 ? 214 GLU A O 1 ATOM 1682 C CB . GLU A 1 206 ? 151.759 60.097 -66.233 1.00 33.78 ? 214 GLU A CB 1 ATOM 1683 C CG . GLU A 1 206 ? 152.288 60.866 -65.028 1.00 43.07 ? 214 GLU A CG 1 ATOM 1684 C CD . GLU A 1 206 ? 151.187 61.678 -64.344 1.00 48.23 ? 214 GLU A CD 1 ATOM 1685 O OE1 . GLU A 1 206 ? 150.457 62.403 -65.063 1.00 51.32 ? 214 GLU A OE1 1 ATOM 1686 O OE2 . GLU A 1 206 ? 151.046 61.589 -63.099 1.00 49.92 ? 214 GLU A OE2 1 ATOM 1687 N N . PRO A 1 207 ? 154.243 57.518 -65.836 1.00 25.06 ? 215 PRO A N 1 ATOM 1688 C CA . PRO A 1 207 ? 154.563 56.339 -65.023 1.00 23.57 ? 215 PRO A CA 1 ATOM 1689 C C . PRO A 1 207 ? 154.016 56.439 -63.597 1.00 23.10 ? 215 PRO A C 1 ATOM 1690 O O . PRO A 1 207 ? 154.035 57.514 -63.004 1.00 22.88 ? 215 PRO A O 1 ATOM 1691 C CB . PRO A 1 207 ? 156.092 56.311 -65.045 1.00 22.24 ? 215 PRO A CB 1 ATOM 1692 C CG . PRO A 1 207 ? 156.430 56.978 -66.325 1.00 22.30 ? 215 PRO A CG 1 ATOM 1693 C CD . PRO A 1 207 ? 155.469 58.133 -66.368 1.00 23.45 ? 215 PRO A CD 1 ATOM 1694 N N . PHE A 1 208 ? 153.524 55.319 -63.069 1.00 22.51 ? 216 PHE A N 1 ATOM 1695 C CA . PHE A 1 208 ? 153.002 55.238 -61.703 1.00 22.45 ? 216 PHE A CA 1 ATOM 1696 C C . PHE A 1 208 ? 151.769 56.083 -61.391 1.00 23.32 ? 216 PHE A C 1 ATOM 1697 O O . PHE A 1 208 ? 151.509 56.374 -60.213 1.00 24.00 ? 216 PHE A O 1 ATOM 1698 C CB . PHE A 1 208 ? 154.098 55.624 -60.704 1.00 21.68 ? 216 PHE A CB 1 ATOM 1699 C CG . PHE A 1 208 ? 155.375 54.868 -60.882 1.00 21.30 ? 216 PHE A CG 1 ATOM 1700 C CD1 . PHE A 1 208 ? 155.415 53.489 -60.689 1.00 20.33 ? 216 PHE A CD1 1 ATOM 1701 C CD2 . PHE A 1 208 ? 156.542 55.535 -61.249 1.00 20.02 ? 216 PHE A CD2 1 ATOM 1702 C CE1 . PHE A 1 208 ? 156.604 52.780 -60.861 1.00 20.74 ? 216 PHE A CE1 1 ATOM 1703 C CE2 . PHE A 1 208 ? 157.737 54.839 -61.424 1.00 20.94 ? 216 PHE A CE2 1 ATOM 1704 C CZ . PHE A 1 208 ? 157.768 53.459 -61.229 1.00 20.93 ? 216 PHE A CZ 1 ATOM 1705 N N . LYS A 1 209 ? 151.002 56.464 -62.410 1.00 22.50 ? 217 LYS A N 1 ATOM 1706 C CA . LYS A 1 209 ? 149.833 57.302 -62.171 1.00 21.41 ? 217 LYS A CA 1 ATOM 1707 C C . LYS A 1 209 ? 148.770 56.713 -61.238 1.00 20.77 ? 217 LYS A C 1 ATOM 1708 O O . LYS A 1 209 ? 148.522 57.258 -60.163 1.00 21.00 ? 217 LYS A O 1 ATOM 1709 C CB . LYS A 1 209 ? 149.194 57.690 -63.497 1.00 22.13 ? 217 LYS A CB 1 ATOM 1710 C CG . LYS A 1 209 ? 148.029 58.660 -63.396 1.00 21.48 ? 217 LYS A CG 1 ATOM 1711 C CD . LYS A 1 209 ? 147.524 58.928 -64.797 1.00 23.90 ? 217 LYS A CD 1 ATOM 1712 C CE . LYS A 1 209 ? 146.325 59.848 -64.832 1.00 26.42 ? 217 LYS A CE 1 ATOM 1713 N NZ . LYS A 1 209 ? 145.811 59.962 -66.232 1.00 24.62 ? 217 LYS A NZ 1 ATOM 1714 N N . PRO A 1 210 ? 148.131 55.596 -61.622 1.00 19.71 ? 218 PRO A N 1 ATOM 1715 C CA . PRO A 1 210 ? 147.110 55.044 -60.727 1.00 19.78 ? 218 PRO A CA 1 ATOM 1716 C C . PRO A 1 210 ? 147.649 54.826 -59.319 1.00 20.23 ? 218 PRO A C 1 ATOM 1717 O O . PRO A 1 210 ? 147.015 55.190 -58.326 1.00 20.05 ? 218 PRO A O 1 ATOM 1718 C CB . PRO A 1 210 ? 146.721 53.731 -61.404 1.00 19.76 ? 218 PRO A CB 1 ATOM 1719 C CG . PRO A 1 210 ? 147.000 53.994 -62.850 1.00 20.45 ? 218 PRO A CG 1 ATOM 1720 C CD . PRO A 1 210 ? 148.322 54.725 -62.792 1.00 20.49 ? 218 PRO A CD 1 ATOM 1721 N N . PHE A 1 211 ? 148.835 54.237 -59.237 1.00 21.42 ? 219 PHE A N 1 ATOM 1722 C CA . PHE A 1 211 ? 149.470 53.971 -57.951 1.00 21.35 ? 219 PHE A CA 1 ATOM 1723 C C . PHE A 1 211 ? 149.687 55.217 -57.091 1.00 20.98 ? 219 PHE A C 1 ATOM 1724 O O . PHE A 1 211 ? 149.313 55.238 -55.912 1.00 19.71 ? 219 PHE A O 1 ATOM 1725 C CB . PHE A 1 211 ? 150.817 53.273 -58.170 1.00 21.11 ? 219 PHE A CB 1 ATOM 1726 C CG . PHE A 1 211 ? 151.601 53.063 -56.902 1.00 21.99 ? 219 PHE A CG 1 ATOM 1727 C CD1 . PHE A 1 211 ? 151.137 52.202 -55.920 1.00 20.93 ? 219 PHE A CD1 1 ATOM 1728 C CD2 . PHE A 1 211 ? 152.807 53.733 -56.693 1.00 21.29 ? 219 PHE A CD2 1 ATOM 1729 C CE1 . PHE A 1 211 ? 151.857 52.015 -54.748 1.00 22.52 ? 219 PHE A CE1 1 ATOM 1730 C CE2 . PHE A 1 211 ? 153.531 53.553 -55.531 1.00 22.14 ? 219 PHE A CE2 1 ATOM 1731 C CZ . PHE A 1 211 ? 153.057 52.690 -54.554 1.00 21.92 ? 219 PHE A CZ 1 ATOM 1732 N N . SER A 1 212 ? 150.297 56.246 -57.681 1.00 19.79 ? 220 SER A N 1 ATOM 1733 C CA . SER A 1 212 ? 150.602 57.476 -56.955 1.00 19.74 ? 220 SER A CA 1 ATOM 1734 C C . SER A 1 212 ? 149.386 58.250 -56.463 1.00 19.16 ? 220 SER A C 1 ATOM 1735 O O . SER A 1 212 ? 149.490 59.027 -55.513 1.00 18.87 ? 220 SER A O 1 ATOM 1736 C CB . SER A 1 212 ? 151.485 58.396 -57.806 1.00 20.41 ? 220 SER A CB 1 ATOM 1737 O OG . SER A 1 212 ? 150.799 58.833 -58.967 1.00 24.52 ? 220 SER A OG 1 ATOM 1738 N N . TYR A 1 213 ? 148.237 58.061 -57.101 1.00 17.84 ? 221 TYR A N 1 ATOM 1739 C CA . TYR A 1 213 ? 147.040 58.764 -56.658 1.00 17.64 ? 221 TYR A CA 1 ATOM 1740 C C . TYR A 1 213 ? 146.419 58.055 -55.464 1.00 17.87 ? 221 TYR A C 1 ATOM 1741 O O . TYR A 1 213 ? 145.952 58.687 -54.513 1.00 17.09 ? 221 TYR A O 1 ATOM 1742 C CB . TYR A 1 213 ? 146.028 58.847 -57.792 1.00 16.40 ? 221 TYR A CB 1 ATOM 1743 C CG . TYR A 1 213 ? 146.153 60.104 -58.612 1.00 19.52 ? 221 TYR A CG 1 ATOM 1744 C CD1 . TYR A 1 213 ? 145.509 61.280 -58.224 1.00 20.16 ? 221 TYR A CD1 1 ATOM 1745 C CD2 . TYR A 1 213 ? 146.903 60.118 -59.788 1.00 20.89 ? 221 TYR A CD2 1 ATOM 1746 C CE1 . TYR A 1 213 ? 145.601 62.436 -58.990 1.00 22.60 ? 221 TYR A CE1 1 ATOM 1747 C CE2 . TYR A 1 213 ? 147.006 61.271 -60.563 1.00 22.10 ? 221 TYR A CE2 1 ATOM 1748 C CZ . TYR A 1 213 ? 146.351 62.425 -60.161 1.00 23.66 ? 221 TYR A CZ 1 ATOM 1749 O OH . TYR A 1 213 ? 146.431 63.562 -60.939 1.00 26.01 ? 221 TYR A OH 1 ATOM 1750 N N . ARG A 1 214 ? 146.440 56.731 -55.517 1.00 17.65 ? 222 ARG A N 1 ATOM 1751 C CA . ARG A 1 214 ? 145.862 55.910 -54.471 1.00 17.58 ? 222 ARG A CA 1 ATOM 1752 C C . ARG A 1 214 ? 146.748 55.706 -53.241 1.00 18.61 ? 222 ARG A C 1 ATOM 1753 O O . ARG A 1 214 ? 146.236 55.634 -52.125 1.00 20.01 ? 222 ARG A O 1 ATOM 1754 C CB . ARG A 1 214 ? 145.465 54.556 -55.063 1.00 15.53 ? 222 ARG A CB 1 ATOM 1755 C CG . ARG A 1 214 ? 144.329 54.654 -56.060 1.00 14.09 ? 222 ARG A CG 1 ATOM 1756 C CD . ARG A 1 214 ? 144.307 53.468 -56.994 1.00 15.77 ? 222 ARG A CD 1 ATOM 1757 N NE . ARG A 1 214 ? 143.159 53.513 -57.894 1.00 17.47 ? 222 ARG A NE 1 ATOM 1758 C CZ . ARG A 1 214 ? 141.955 53.044 -57.590 1.00 17.12 ? 222 ARG A CZ 1 ATOM 1759 N NH1 . ARG A 1 214 ? 141.741 52.488 -56.408 1.00 16.73 ? 222 ARG A NH1 1 ATOM 1760 N NH2 . ARG A 1 214 ? 140.966 53.127 -58.468 1.00 18.53 ? 222 ARG A NH2 1 ATOM 1761 N N . TYR A 1 215 ? 148.063 55.626 -53.422 1.00 18.83 ? 223 TYR A N 1 ATOM 1762 C CA . TYR A 1 215 ? 148.940 55.397 -52.278 1.00 18.47 ? 223 TYR A CA 1 ATOM 1763 C C . TYR A 1 215 ? 149.993 56.472 -52.023 1.00 19.05 ? 223 TYR A C 1 ATOM 1764 O O . TYR A 1 215 ? 150.950 56.627 -52.786 1.00 21.28 ? 223 TYR A O 1 ATOM 1765 C CB . TYR A 1 215 ? 149.605 54.020 -52.415 1.00 17.24 ? 223 TYR A CB 1 ATOM 1766 C CG . TYR A 1 215 ? 148.586 52.910 -52.482 1.00 16.01 ? 223 TYR A CG 1 ATOM 1767 C CD1 . TYR A 1 215 ? 148.001 52.544 -53.690 1.00 14.59 ? 223 TYR A CD1 1 ATOM 1768 C CD2 . TYR A 1 215 ? 148.117 52.307 -51.317 1.00 16.98 ? 223 TYR A CD2 1 ATOM 1769 C CE1 . TYR A 1 215 ? 146.965 51.615 -53.735 1.00 12.04 ? 223 TYR A CE1 1 ATOM 1770 C CE2 . TYR A 1 215 ? 147.082 51.382 -51.351 1.00 14.57 ? 223 TYR A CE2 1 ATOM 1771 C CZ . TYR A 1 215 ? 146.513 51.045 -52.554 1.00 11.27 ? 223 TYR A CZ 1 ATOM 1772 O OH . TYR A 1 215 ? 145.474 50.154 -52.550 1.00 11.00 ? 223 TYR A OH 1 ATOM 1773 N N . HIS A 1 216 ? 149.811 57.223 -50.944 1.00 18.11 ? 224 HIS A N 1 ATOM 1774 C CA . HIS A 1 216 ? 150.762 58.263 -50.597 1.00 18.43 ? 224 HIS A CA 1 ATOM 1775 C C . HIS A 1 216 ? 151.735 57.753 -49.550 1.00 19.11 ? 224 HIS A C 1 ATOM 1776 O O . HIS A 1 216 ? 151.436 56.826 -48.808 1.00 20.66 ? 224 HIS A O 1 ATOM 1777 C CB . HIS A 1 216 ? 150.034 59.508 -50.086 1.00 18.42 ? 224 HIS A CB 1 ATOM 1778 C CG . HIS A 1 216 ? 149.360 60.290 -51.170 1.00 19.43 ? 224 HIS A CG 1 ATOM 1779 N ND1 . HIS A 1 216 ? 148.940 61.592 -51.006 1.00 20.38 ? 224 HIS A ND1 1 ATOM 1780 C CD2 . HIS A 1 216 ? 149.051 59.954 -52.445 1.00 19.16 ? 224 HIS A CD2 1 ATOM 1781 C CE1 . HIS A 1 216 ? 148.403 62.026 -52.134 1.00 19.99 ? 224 HIS A CE1 1 ATOM 1782 N NE2 . HIS A 1 216 ? 148.459 61.050 -53.022 1.00 20.12 ? 224 HIS A NE2 1 ATOM 1783 N N . VAL A 1 217 ? 152.913 58.359 -49.508 1.00 18.96 ? 225 VAL A N 1 ATOM 1784 C CA . VAL A 1 217 ? 153.950 57.978 -48.558 1.00 18.00 ? 225 VAL A CA 1 ATOM 1785 C C . VAL A 1 217 ? 154.571 59.263 -48.001 1.00 18.74 ? 225 VAL A C 1 ATOM 1786 O O . VAL A 1 217 ? 154.512 60.311 -48.644 1.00 19.81 ? 225 VAL A O 1 ATOM 1787 C CB . VAL A 1 217 ? 155.035 57.105 -49.250 1.00 15.55 ? 225 VAL A CB 1 ATOM 1788 C CG1 . VAL A 1 217 ? 154.395 55.855 -49.827 1.00 14.05 ? 225 VAL A CG1 1 ATOM 1789 C CG2 . VAL A 1 217 ? 155.714 57.887 -50.359 1.00 14.00 ? 225 VAL A CG2 1 ATOM 1790 N N . PRO A 1 218 ? 155.169 59.201 -46.798 1.00 18.43 ? 226 PRO A N 1 ATOM 1791 C CA . PRO A 1 218 ? 155.796 60.359 -46.153 1.00 19.69 ? 226 PRO A CA 1 ATOM 1792 C C . PRO A 1 218 ? 157.211 60.605 -46.667 1.00 20.92 ? 226 PRO A C 1 ATOM 1793 O O . PRO A 1 218 ? 158.145 60.752 -45.882 1.00 22.29 ? 226 PRO A O 1 ATOM 1794 C CB . PRO A 1 218 ? 155.805 59.947 -44.697 1.00 18.94 ? 226 PRO A CB 1 ATOM 1795 C CG . PRO A 1 218 ? 156.198 58.499 -44.815 1.00 18.29 ? 226 PRO A CG 1 ATOM 1796 C CD . PRO A 1 218 ? 155.282 58.013 -45.933 1.00 19.00 ? 226 PRO A CD 1 ATOM 1797 N N . TYR A 1 219 ? 157.370 60.669 -47.981 1.00 22.26 ? 227 TYR A N 1 ATOM 1798 C CA . TYR A 1 219 ? 158.696 60.854 -48.560 1.00 23.71 ? 227 TYR A CA 1 ATOM 1799 C C . TYR A 1 219 ? 159.408 62.151 -48.190 1.00 24.05 ? 227 TYR A C 1 ATOM 1800 O O . TYR A 1 219 ? 160.639 62.176 -48.059 1.00 23.14 ? 227 TYR A O 1 ATOM 1801 C CB . TYR A 1 219 ? 158.622 60.718 -50.079 1.00 23.02 ? 227 TYR A CB 1 ATOM 1802 C CG . TYR A 1 219 ? 157.839 61.801 -50.779 1.00 21.88 ? 227 TYR A CG 1 ATOM 1803 C CD1 . TYR A 1 219 ? 158.466 62.962 -51.231 1.00 21.60 ? 227 TYR A CD1 1 ATOM 1804 C CD2 . TYR A 1 219 ? 156.487 61.633 -51.053 1.00 20.41 ? 227 TYR A CD2 1 ATOM 1805 C CE1 . TYR A 1 219 ? 157.766 63.921 -51.956 1.00 20.48 ? 227 TYR A CE1 1 ATOM 1806 C CE2 . TYR A 1 219 ? 155.780 62.582 -51.773 1.00 19.14 ? 227 TYR A CE2 1 ATOM 1807 C CZ . TYR A 1 219 ? 156.425 63.722 -52.226 1.00 20.23 ? 227 TYR A CZ 1 ATOM 1808 O OH . TYR A 1 219 ? 155.744 64.648 -52.984 1.00 18.81 ? 227 TYR A OH 1 ATOM 1809 N N . GLU A 1 220 ? 158.642 63.220 -48.016 1.00 24.60 ? 228 GLU A N 1 ATOM 1810 C CA . GLU A 1 220 ? 159.218 64.508 -47.662 1.00 25.78 ? 228 GLU A CA 1 ATOM 1811 C C . GLU A 1 220 ? 159.929 64.448 -46.311 1.00 24.19 ? 228 GLU A C 1 ATOM 1812 O O . GLU A 1 220 ? 160.874 65.191 -46.069 1.00 23.38 ? 228 GLU A O 1 ATOM 1813 C CB . GLU A 1 220 ? 158.123 65.583 -47.633 1.00 30.69 ? 228 GLU A CB 1 ATOM 1814 C CG . GLU A 1 220 ? 157.265 65.624 -48.896 1.00 38.18 ? 228 GLU A CG 1 ATOM 1815 C CD . GLU A 1 220 ? 155.904 64.949 -48.721 1.00 44.24 ? 228 GLU A CD 1 ATOM 1816 O OE1 . GLU A 1 220 ? 155.831 63.895 -48.038 1.00 43.81 ? 228 GLU A OE1 1 ATOM 1817 O OE2 . GLU A 1 220 ? 154.912 65.485 -49.280 1.00 46.70 ? 228 GLU A OE2 1 ATOM 1818 N N . ALA A 1 221 ? 159.481 63.554 -45.438 1.00 23.27 ? 229 ALA A N 1 ATOM 1819 C CA . ALA A 1 221 ? 160.079 63.423 -44.116 1.00 23.26 ? 229 ALA A CA 1 ATOM 1820 C C . ALA A 1 221 ? 161.566 63.080 -44.171 1.00 24.34 ? 229 ALA A C 1 ATOM 1821 O O . ALA A 1 221 ? 162.310 63.398 -43.245 1.00 25.15 ? 229 ALA A O 1 ATOM 1822 C CB . ALA A 1 221 ? 159.329 62.368 -43.306 1.00 21.49 ? 229 ALA A CB 1 ATOM 1823 N N . SER A 1 222 ? 162.003 62.434 -45.248 1.00 23.78 ? 230 SER A N 1 ATOM 1824 C CA . SER A 1 222 ? 163.406 62.065 -45.368 1.00 23.34 ? 230 SER A CA 1 ATOM 1825 C C . SER A 1 222 ? 164.171 62.888 -46.399 1.00 24.38 ? 230 SER A C 1 ATOM 1826 O O . SER A 1 222 ? 165.232 62.463 -46.872 1.00 24.48 ? 230 SER A O 1 ATOM 1827 C CB . SER A 1 222 ? 163.539 60.580 -45.706 1.00 23.04 ? 230 SER A CB 1 ATOM 1828 O OG . SER A 1 222 ? 162.822 60.266 -46.885 1.00 23.01 ? 230 SER A OG 1 ATOM 1829 N N . GLN A 1 223 ? 163.643 64.057 -46.751 1.00 24.21 ? 231 GLN A N 1 ATOM 1830 C CA . GLN A 1 223 ? 164.331 64.904 -47.717 1.00 26.32 ? 231 GLN A CA 1 ATOM 1831 C C . GLN A 1 223 ? 164.260 64.368 -49.135 1.00 25.10 ? 231 GLN A C 1 ATOM 1832 O O . GLN A 1 223 ? 165.023 64.809 -49.994 1.00 24.87 ? 231 GLN A O 1 ATOM 1833 C CB . GLN A 1 223 ? 165.815 65.054 -47.350 1.00 31.24 ? 231 GLN A CB 1 ATOM 1834 C CG . GLN A 1 223 ? 166.189 66.354 -46.671 1.00 36.61 ? 231 GLN A CG 1 ATOM 1835 C CD . GLN A 1 223 ? 165.383 66.602 -45.429 1.00 39.95 ? 231 GLN A CD 1 ATOM 1836 O OE1 . GLN A 1 223 ? 165.411 65.806 -44.482 1.00 42.79 ? 231 GLN A OE1 1 ATOM 1837 N NE2 . GLN A 1 223 ? 164.649 67.710 -45.418 1.00 41.92 ? 231 GLN A NE2 1 ATOM 1838 N N . SER A 1 224 ? 163.380 63.406 -49.388 1.00 23.16 ? 232 SER A N 1 ATOM 1839 C CA . SER A 1 224 ? 163.257 62.886 -50.745 1.00 21.93 ? 232 SER A CA 1 ATOM 1840 C C . SER A 1 224 ? 162.392 63.846 -51.561 1.00 21.33 ? 232 SER A C 1 ATOM 1841 O O . SER A 1 224 ? 161.555 64.559 -51.015 1.00 22.37 ? 232 SER A O 1 ATOM 1842 C CB . SER A 1 224 ? 162.624 61.496 -50.736 1.00 22.03 ? 232 SER A CB 1 ATOM 1843 O OG . SER A 1 224 ? 162.164 61.130 -52.027 1.00 19.74 ? 232 SER A OG 1 ATOM 1844 N N . THR A 1 225 ? 162.593 63.873 -52.869 1.00 19.50 ? 233 THR A N 1 ATOM 1845 C CA . THR A 1 225 ? 161.810 64.754 -53.718 1.00 17.90 ? 233 THR A CA 1 ATOM 1846 C C . THR A 1 225 ? 160.833 63.943 -54.560 1.00 18.14 ? 233 THR A C 1 ATOM 1847 O O . THR A 1 225 ? 160.246 64.452 -55.514 1.00 18.11 ? 233 THR A O 1 ATOM 1848 C CB . THR A 1 225 ? 162.726 65.568 -54.654 1.00 17.87 ? 233 THR A CB 1 ATOM 1849 O OG1 . THR A 1 225 ? 163.531 64.677 -55.430 1.00 18.24 ? 233 THR A OG1 1 ATOM 1850 C CG2 . THR A 1 225 ? 163.647 66.467 -53.853 1.00 17.10 ? 233 THR A CG2 1 ATOM 1851 N N . SER A 1 226 ? 160.643 62.682 -54.187 1.00 18.09 ? 234 SER A N 1 ATOM 1852 C CA . SER A 1 226 ? 159.759 61.801 -54.934 1.00 18.65 ? 234 SER A CA 1 ATOM 1853 C C . SER A 1 226 ? 159.174 60.684 -54.068 1.00 19.21 ? 234 SER A C 1 ATOM 1854 O O . SER A 1 226 ? 159.849 60.149 -53.178 1.00 20.71 ? 234 SER A O 1 ATOM 1855 C CB . SER A 1 226 ? 160.543 61.198 -56.101 1.00 20.28 ? 234 SER A CB 1 ATOM 1856 O OG . SER A 1 226 ? 159.765 60.254 -56.810 1.00 25.57 ? 234 SER A OG 1 ATOM 1857 N N . PRO A 1 227 ? 157.910 60.302 -54.323 1.00 17.63 ? 235 PRO A N 1 ATOM 1858 C CA . PRO A 1 227 ? 157.288 59.236 -53.527 1.00 17.47 ? 235 PRO A CA 1 ATOM 1859 C C . PRO A 1 227 ? 157.770 57.812 -53.817 1.00 18.46 ? 235 PRO A C 1 ATOM 1860 O O . PRO A 1 227 ? 157.338 56.871 -53.145 1.00 20.10 ? 235 PRO A O 1 ATOM 1861 C CB . PRO A 1 227 ? 155.797 59.404 -53.834 1.00 16.00 ? 235 PRO A CB 1 ATOM 1862 C CG . PRO A 1 227 ? 155.802 59.889 -55.242 1.00 12.93 ? 235 PRO A CG 1 ATOM 1863 C CD . PRO A 1 227 ? 156.931 60.902 -55.249 1.00 14.82 ? 235 PRO A CD 1 ATOM 1864 N N . PHE A 1 228 ? 158.667 57.644 -54.787 1.00 17.51 ? 236 PHE A N 1 ATOM 1865 C CA . PHE A 1 228 ? 159.129 56.299 -55.133 1.00 16.79 ? 236 PHE A CA 1 ATOM 1866 C C . PHE A 1 228 ? 160.335 55.788 -54.378 1.00 16.13 ? 236 PHE A C 1 ATOM 1867 O O . PHE A 1 228 ? 160.712 54.631 -54.518 1.00 15.53 ? 236 PHE A O 1 ATOM 1868 C CB . PHE A 1 228 ? 159.362 56.220 -56.635 1.00 16.65 ? 236 PHE A CB 1 ATOM 1869 C CG . PHE A 1 228 ? 158.247 56.821 -57.419 1.00 17.01 ? 236 PHE A CG 1 ATOM 1870 C CD1 . PHE A 1 228 ? 158.477 57.896 -58.270 1.00 17.61 ? 236 PHE A CD1 1 ATOM 1871 C CD2 . PHE A 1 228 ? 156.943 56.384 -57.225 1.00 16.24 ? 236 PHE A CD2 1 ATOM 1872 C CE1 . PHE A 1 228 ? 157.422 58.533 -58.903 1.00 16.30 ? 236 PHE A CE1 1 ATOM 1873 C CE2 . PHE A 1 228 ? 155.881 57.019 -57.856 1.00 16.57 ? 236 PHE A CE2 1 ATOM 1874 C CZ . PHE A 1 228 ? 156.124 58.094 -58.692 1.00 16.94 ? 236 PHE A CZ 1 ATOM 1875 N N . TRP A 1 229 ? 160.942 56.664 -53.587 1.00 17.48 ? 237 TRP A N 1 ATOM 1876 C CA . TRP A 1 229 ? 162.081 56.302 -52.753 1.00 17.12 ? 237 TRP A CA 1 ATOM 1877 C C . TRP A 1 229 ? 162.005 57.220 -51.546 1.00 17.23 ? 237 TRP A C 1 ATOM 1878 O O . TRP A 1 229 ? 161.717 58.412 -51.669 1.00 17.38 ? 237 TRP A O 1 ATOM 1879 C CB . TRP A 1 229 ? 163.413 56.450 -53.508 1.00 15.95 ? 237 TRP A CB 1 ATOM 1880 C CG . TRP A 1 229 ? 163.752 57.833 -53.995 1.00 17.24 ? 237 TRP A CG 1 ATOM 1881 C CD1 . TRP A 1 229 ? 164.356 58.832 -53.282 1.00 17.56 ? 237 TRP A CD1 1 ATOM 1882 C CD2 . TRP A 1 229 ? 163.540 58.354 -55.313 1.00 17.08 ? 237 TRP A CD2 1 ATOM 1883 N NE1 . TRP A 1 229 ? 164.535 59.942 -54.074 1.00 16.16 ? 237 TRP A NE1 1 ATOM 1884 C CE2 . TRP A 1 229 ? 164.040 59.679 -55.324 1.00 17.12 ? 237 TRP A CE2 1 ATOM 1885 C CE3 . TRP A 1 229 ? 162.969 57.835 -56.484 1.00 16.85 ? 237 TRP A CE3 1 ATOM 1886 C CZ2 . TRP A 1 229 ? 163.997 60.488 -56.465 1.00 16.40 ? 237 TRP A CZ2 1 ATOM 1887 C CZ3 . TRP A 1 229 ? 162.925 58.640 -57.623 1.00 17.77 ? 237 TRP A CZ3 1 ATOM 1888 C CH2 . TRP A 1 229 ? 163.434 59.955 -57.601 1.00 17.81 ? 237 TRP A CH2 1 ATOM 1889 N N . TYR A 1 230 ? 162.218 56.643 -50.373 1.00 17.08 ? 238 TYR A N 1 ATOM 1890 C CA . TYR A 1 230 ? 162.148 57.389 -49.127 1.00 17.12 ? 238 TYR A CA 1 ATOM 1891 C C . TYR A 1 230 ? 162.524 56.422 -48.023 1.00 17.66 ? 238 TYR A C 1 ATOM 1892 O O . TYR A 1 230 ? 162.705 55.227 -48.273 1.00 19.24 ? 238 TYR A O 1 ATOM 1893 C CB . TYR A 1 230 ? 160.720 57.875 -48.896 1.00 16.71 ? 238 TYR A CB 1 ATOM 1894 C CG . TYR A 1 230 ? 159.711 56.739 -48.808 1.00 17.70 ? 238 TYR A CG 1 ATOM 1895 C CD1 . TYR A 1 230 ? 159.224 56.114 -49.959 1.00 18.30 ? 238 TYR A CD1 1 ATOM 1896 C CD2 . TYR A 1 230 ? 159.269 56.269 -47.571 1.00 17.67 ? 238 TYR A CD2 1 ATOM 1897 C CE1 . TYR A 1 230 ? 158.319 55.044 -49.878 1.00 18.49 ? 238 TYR A CE1 1 ATOM 1898 C CE2 . TYR A 1 230 ? 158.371 55.206 -47.478 1.00 18.19 ? 238 TYR A CE2 1 ATOM 1899 C CZ . TYR A 1 230 ? 157.899 54.595 -48.632 1.00 18.51 ? 238 TYR A CZ 1 ATOM 1900 O OH . TYR A 1 230 ? 157.017 53.533 -48.530 1.00 17.25 ? 238 TYR A OH 1 ATOM 1901 N N . SER A 1 231 ? 162.640 56.929 -46.803 1.00 17.78 ? 239 SER A N 1 ATOM 1902 C CA . SER A 1 231 ? 162.967 56.064 -45.679 1.00 18.78 ? 239 SER A CA 1 ATOM 1903 C C . SER A 1 231 ? 162.097 56.431 -44.498 1.00 18.49 ? 239 SER A C 1 ATOM 1904 O O . SER A 1 231 ? 161.485 57.502 -44.472 1.00 17.99 ? 239 SER A O 1 ATOM 1905 C CB . SER A 1 231 ? 164.438 56.213 -45.276 1.00 18.95 ? 239 SER A CB 1 ATOM 1906 O OG . SER A 1 231 ? 164.677 57.503 -44.743 1.00 21.29 ? 239 SER A OG 1 ATOM 1907 N N . ILE A 1 232 ? 162.033 55.525 -43.532 1.00 17.97 ? 240 ILE A N 1 ATOM 1908 C CA . ILE A 1 232 ? 161.280 55.754 -42.314 1.00 18.83 ? 240 ILE A CA 1 ATOM 1909 C C . ILE A 1 232 ? 161.979 54.996 -41.209 1.00 19.55 ? 240 ILE A C 1 ATOM 1910 O O . ILE A 1 232 ? 162.701 54.021 -41.457 1.00 18.66 ? 240 ILE A O 1 ATOM 1911 C CB . ILE A 1 232 ? 159.836 55.212 -42.370 1.00 18.52 ? 240 ILE A CB 1 ATOM 1912 C CG1 . ILE A 1 232 ? 159.862 53.713 -42.653 1.00 19.76 ? 240 ILE A CG1 1 ATOM 1913 C CG2 . ILE A 1 232 ? 159.020 55.974 -43.385 1.00 19.68 ? 240 ILE A CG2 1 ATOM 1914 C CD1 . ILE A 1 232 ? 158.568 53.023 -42.324 1.00 20.28 ? 240 ILE A CD1 1 ATOM 1915 N N . LYS A 1 233 ? 161.760 55.463 -39.989 1.00 19.96 ? 241 LYS A N 1 ATOM 1916 C CA . LYS A 1 233 ? 162.315 54.831 -38.812 1.00 20.95 ? 241 LYS A CA 1 ATOM 1917 C C . LYS A 1 233 ? 161.109 54.290 -38.049 1.00 21.16 ? 241 LYS A C 1 ATOM 1918 O O . LYS A 1 233 ? 160.096 54.978 -37.923 1.00 21.03 ? 241 LYS A O 1 ATOM 1919 C CB . LYS A 1 233 ? 163.038 55.857 -37.936 1.00 21.53 ? 241 LYS A CB 1 ATOM 1920 C CG . LYS A 1 233 ? 164.318 56.436 -38.509 1.00 22.29 ? 241 LYS A CG 1 ATOM 1921 C CD . LYS A 1 233 ? 164.977 57.359 -37.486 1.00 24.34 ? 241 LYS A CD 1 ATOM 1922 C CE . LYS A 1 233 ? 166.259 57.974 -38.032 1.00 29.60 ? 241 LYS A CE 1 ATOM 1923 N NZ . LYS A 1 233 ? 167.086 58.626 -36.965 1.00 31.54 ? 241 LYS A NZ 1 ATOM 1924 N N . ARG A 1 234 ? 161.200 53.059 -37.565 1.00 20.37 ? 242 ARG A N 1 ATOM 1925 C CA . ARG A 1 234 ? 160.115 52.483 -36.786 1.00 20.82 ? 242 ARG A CA 1 ATOM 1926 C C . ARG A 1 234 ? 160.737 51.524 -35.789 1.00 21.03 ? 242 ARG A C 1 ATOM 1927 O O . ARG A 1 234 ? 161.386 50.551 -36.179 1.00 21.58 ? 242 ARG A O 1 ATOM 1928 C CB . ARG A 1 234 ? 159.105 51.761 -37.683 1.00 22.14 ? 242 ARG A CB 1 ATOM 1929 C CG . ARG A 1 234 ? 158.031 50.983 -36.900 1.00 23.28 ? 242 ARG A CG 1 ATOM 1930 C CD . ARG A 1 234 ? 156.815 50.653 -37.759 1.00 22.36 ? 242 ARG A CD 1 ATOM 1931 N NE . ARG A 1 234 ? 156.012 51.849 -37.985 1.00 24.40 ? 242 ARG A NE 1 ATOM 1932 C CZ . ARG A 1 234 ? 154.748 51.994 -37.597 1.00 24.01 ? 242 ARG A CZ 1 ATOM 1933 N NH1 . ARG A 1 234 ? 154.127 51.007 -36.962 1.00 22.38 ? 242 ARG A NH1 1 ATOM 1934 N NH2 . ARG A 1 234 ? 154.117 53.141 -37.823 1.00 21.30 ? 242 ARG A NH2 1 ATOM 1935 N N . ALA A 1 235 ? 160.536 51.813 -34.506 1.00 20.01 ? 243 ALA A N 1 ATOM 1936 C CA . ALA A 1 235 ? 161.101 51.010 -33.435 1.00 19.88 ? 243 ALA A CA 1 ATOM 1937 C C . ALA A 1 235 ? 162.625 51.036 -33.583 1.00 20.14 ? 243 ALA A C 1 ATOM 1938 O O . ALA A 1 235 ? 163.220 52.103 -33.674 1.00 20.62 ? 243 ALA A O 1 ATOM 1939 C CB . ALA A 1 235 ? 160.573 49.586 -33.501 1.00 18.75 ? 243 ALA A CB 1 ATOM 1940 N N . SER A 1 236 ? 163.255 49.870 -33.622 1.00 21.31 ? 244 SER A N 1 ATOM 1941 C CA . SER A 1 236 ? 164.710 49.793 -33.746 1.00 22.97 ? 244 SER A CA 1 ATOM 1942 C C . SER A 1 236 ? 165.166 49.577 -35.181 1.00 23.55 ? 244 SER A C 1 ATOM 1943 O O . SER A 1 236 ? 166.283 49.110 -35.417 1.00 24.98 ? 244 SER A O 1 ATOM 1944 C CB . SER A 1 236 ? 165.237 48.645 -32.894 1.00 23.54 ? 244 SER A CB 1 ATOM 1945 O OG . SER A 1 236 ? 164.604 47.429 -33.266 1.00 27.08 ? 244 SER A OG 1 ATOM 1946 N N . ALA A 1 237 ? 164.310 49.910 -36.141 1.00 23.48 ? 245 ALA A N 1 ATOM 1947 C CA . ALA A 1 237 ? 164.656 49.710 -37.539 1.00 22.44 ? 245 ALA A CA 1 ATOM 1948 C C . ALA A 1 237 ? 164.597 50.973 -38.360 1.00 22.93 ? 245 ALA A C 1 ATOM 1949 O O . ALA A 1 237 ? 163.717 51.825 -38.185 1.00 23.59 ? 245 ALA A O 1 ATOM 1950 C CB . ALA A 1 237 ? 163.745 48.666 -38.161 1.00 22.22 ? 245 ALA A CB 1 ATOM 1951 N N . HIS A 1 238 ? 165.567 51.089 -39.255 1.00 22.36 ? 246 HIS A N 1 ATOM 1952 C CA . HIS A 1 238 ? 165.650 52.211 -40.170 1.00 21.18 ? 246 HIS A CA 1 ATOM 1953 C C . HIS A 1 238 ? 165.466 51.516 -41.516 1.00 21.87 ? 246 HIS A C 1 ATOM 1954 O O . HIS A 1 238 ? 166.286 50.678 -41.926 1.00 20.78 ? 246 HIS A O 1 ATOM 1955 C CB . HIS A 1 238 ? 167.012 52.884 -40.068 1.00 22.06 ? 246 HIS A CB 1 ATOM 1956 C CG . HIS A 1 238 ? 167.118 54.150 -40.853 1.00 24.34 ? 246 HIS A CG 1 ATOM 1957 N ND1 . HIS A 1 238 ? 167.807 55.252 -40.394 1.00 25.73 ? 246 HIS A ND1 1 ATOM 1958 C CD2 . HIS A 1 238 ? 166.641 54.488 -42.075 1.00 24.93 ? 246 HIS A CD2 1 ATOM 1959 C CE1 . HIS A 1 238 ? 167.750 56.214 -41.297 1.00 25.55 ? 246 HIS A CE1 1 ATOM 1960 N NE2 . HIS A 1 238 ? 167.048 55.776 -42.327 1.00 25.88 ? 246 HIS A NE2 1 ATOM 1961 N N . ILE A 1 239 ? 164.360 51.849 -42.174 1.00 20.59 ? 247 ILE A N 1 ATOM 1962 C CA . ILE A 1 239 ? 163.985 51.249 -43.438 1.00 17.56 ? 247 ILE A CA 1 ATOM 1963 C C . ILE A 1 239 ? 164.176 52.215 -44.588 1.00 18.79 ? 247 ILE A C 1 ATOM 1964 O O . ILE A 1 239 ? 163.761 53.376 -44.515 1.00 18.39 ? 247 ILE A O 1 ATOM 1965 C CB . ILE A 1 239 ? 162.523 50.814 -43.360 1.00 16.49 ? 247 ILE A CB 1 ATOM 1966 C CG1 . ILE A 1 239 ? 162.386 49.754 -42.267 1.00 14.55 ? 247 ILE A CG1 1 ATOM 1967 C CG2 . ILE A 1 239 ? 162.038 50.320 -44.710 1.00 13.00 ? 247 ILE A CG2 1 ATOM 1968 C CD1 . ILE A 1 239 ? 161.052 49.766 -41.568 1.00 15.11 ? 247 ILE A CD1 1 ATOM 1969 N N . ILE A 1 240 ? 164.808 51.721 -45.647 1.00 18.54 ? 248 ILE A N 1 ATOM 1970 C CA . ILE A 1 240 ? 165.073 52.521 -46.834 1.00 19.20 ? 248 ILE A CA 1 ATOM 1971 C C . ILE A 1 240 ? 164.373 51.880 -48.020 1.00 18.82 ? 248 ILE A C 1 ATOM 1972 O O . ILE A 1 240 ? 164.608 50.704 -48.319 1.00 19.96 ? 248 ILE A O 1 ATOM 1973 C CB . ILE A 1 240 ? 166.591 52.597 -47.123 1.00 19.44 ? 248 ILE A CB 1 ATOM 1974 C CG1 . ILE A 1 240 ? 167.293 53.351 -45.993 1.00 19.54 ? 248 ILE A CG1 1 ATOM 1975 C CG2 . ILE A 1 240 ? 166.832 53.277 -48.454 1.00 16.39 ? 248 ILE A CG2 1 ATOM 1976 C CD1 . ILE A 1 240 ? 168.776 53.527 -46.196 1.00 19.84 ? 248 ILE A CD1 1 ATOM 1977 N N . VAL A 1 241 ? 163.515 52.651 -48.686 1.00 18.32 ? 249 VAL A N 1 ATOM 1978 C CA . VAL A 1 241 ? 162.772 52.153 -49.839 1.00 17.16 ? 249 VAL A CA 1 ATOM 1979 C C . VAL A 1 241 ? 163.315 52.728 -51.140 1.00 17.09 ? 249 VAL A C 1 ATOM 1980 O O . VAL A 1 241 ? 163.359 53.951 -51.320 1.00 16.87 ? 249 VAL A O 1 ATOM 1981 C CB . VAL A 1 241 ? 161.279 52.509 -49.737 1.00 16.15 ? 249 VAL A CB 1 ATOM 1982 C CG1 . VAL A 1 241 ? 160.506 51.823 -50.852 1.00 16.04 ? 249 VAL A CG1 1 ATOM 1983 C CG2 . VAL A 1 241 ? 160.738 52.096 -48.377 1.00 16.20 ? 249 VAL A CG2 1 ATOM 1984 N N . LEU A 1 242 ? 163.720 51.840 -52.044 1.00 16.55 ? 250 LEU A N 1 ATOM 1985 C CA . LEU A 1 242 ? 164.256 52.243 -53.339 1.00 16.71 ? 250 LEU A CA 1 ATOM 1986 C C . LEU A 1 242 ? 163.311 51.896 -54.483 1.00 17.13 ? 250 LEU A C 1 ATOM 1987 O O . LEU A 1 242 ? 162.469 50.992 -54.368 1.00 17.66 ? 250 LEU A O 1 ATOM 1988 C CB . LEU A 1 242 ? 165.615 51.585 -53.578 1.00 15.94 ? 250 LEU A CB 1 ATOM 1989 C CG . LEU A 1 242 ? 166.696 52.022 -52.585 1.00 16.57 ? 250 LEU A CG 1 ATOM 1990 C CD1 . LEU A 1 242 ? 167.995 51.311 -52.892 1.00 15.31 ? 250 LEU A CD1 1 ATOM 1991 C CD2 . LEU A 1 242 ? 166.879 53.532 -52.666 1.00 15.51 ? 250 LEU A CD2 1 ATOM 1992 N N . SER A 1 243 ? 163.465 52.619 -55.588 1.00 15.55 ? 251 SER A N 1 ATOM 1993 C CA . SER A 1 243 ? 162.636 52.425 -56.761 1.00 14.41 ? 251 SER A CA 1 ATOM 1994 C C . SER A 1 243 ? 163.409 51.752 -57.895 1.00 15.20 ? 251 SER A C 1 ATOM 1995 O O . SER A 1 243 ? 164.218 52.391 -58.576 1.00 15.34 ? 251 SER A O 1 ATOM 1996 C CB . SER A 1 243 ? 162.120 53.778 -57.228 1.00 14.09 ? 251 SER A CB 1 ATOM 1997 O OG . SER A 1 243 ? 161.324 53.629 -58.380 1.00 15.77 ? 251 SER A OG 1 ATOM 1998 N N . SER A 1 244 ? 163.163 50.465 -58.105 1.00 15.54 ? 252 SER A N 1 ATOM 1999 C CA . SER A 1 244 ? 163.858 49.739 -59.161 1.00 15.38 ? 252 SER A CA 1 ATOM 2000 C C . SER A 1 244 ? 163.573 50.315 -60.538 1.00 16.09 ? 252 SER A C 1 ATOM 2001 O O . SER A 1 244 ? 164.362 50.129 -61.474 1.00 15.25 ? 252 SER A O 1 ATOM 2002 C CB . SER A 1 244 ? 163.454 48.262 -59.158 1.00 14.94 ? 252 SER A CB 1 ATOM 2003 O OG . SER A 1 244 ? 163.895 47.604 -57.984 1.00 15.44 ? 252 SER A OG 1 ATOM 2004 N N . TYR A 1 245 ? 162.460 51.026 -60.670 1.00 14.96 ? 253 TYR A N 1 ATOM 2005 C CA . TYR A 1 245 ? 162.103 51.554 -61.968 1.00 15.68 ? 253 TYR A CA 1 ATOM 2006 C C . TYR A 1 245 ? 162.154 53.070 -62.162 1.00 16.85 ? 253 TYR A C 1 ATOM 2007 O O . TYR A 1 245 ? 161.407 53.640 -62.964 1.00 17.55 ? 253 TYR A O 1 ATOM 2008 C CB . TYR A 1 245 ? 160.746 50.951 -62.370 1.00 13.52 ? 253 TYR A CB 1 ATOM 2009 C CG . TYR A 1 245 ? 160.800 49.439 -62.273 1.00 12.18 ? 253 TYR A CG 1 ATOM 2010 C CD1 . TYR A 1 245 ? 160.214 48.772 -61.206 1.00 10.32 ? 253 TYR A CD1 1 ATOM 2011 C CD2 . TYR A 1 245 ? 161.551 48.688 -63.183 1.00 11.57 ? 253 TYR A CD2 1 ATOM 2012 C CE1 . TYR A 1 245 ? 160.368 47.402 -61.041 1.00 10.87 ? 253 TYR A CE1 1 ATOM 2013 C CE2 . TYR A 1 245 ? 161.717 47.308 -63.023 1.00 10.95 ? 253 TYR A CE2 1 ATOM 2014 C CZ . TYR A 1 245 ? 161.122 46.679 -61.945 1.00 10.34 ? 253 TYR A CZ 1 ATOM 2015 O OH . TYR A 1 245 ? 161.283 45.330 -61.763 1.00 12.36 ? 253 TYR A OH 1 ATOM 2016 N N . SER A 1 246 ? 163.060 53.719 -61.436 1.00 16.71 ? 254 SER A N 1 ATOM 2017 C CA . SER A 1 246 ? 163.265 55.164 -61.569 1.00 16.82 ? 254 SER A CA 1 ATOM 2018 C C . SER A 1 246 ? 164.738 55.362 -61.918 1.00 16.72 ? 254 SER A C 1 ATOM 2019 O O . SER A 1 246 ? 165.524 54.416 -61.881 1.00 16.19 ? 254 SER A O 1 ATOM 2020 C CB . SER A 1 246 ? 162.966 55.897 -60.261 1.00 15.83 ? 254 SER A CB 1 ATOM 2021 O OG . SER A 1 246 ? 161.620 55.706 -59.872 1.00 15.95 ? 254 SER A OG 1 ATOM 2022 N N . ALA A 1 247 ? 165.113 56.586 -62.266 1.00 16.70 ? 255 ALA A N 1 ATOM 2023 C CA . ALA A 1 247 ? 166.504 56.862 -62.592 1.00 16.75 ? 255 ALA A CA 1 ATOM 2024 C C . ALA A 1 247 ? 167.381 56.610 -61.364 1.00 16.01 ? 255 ALA A C 1 ATOM 2025 O O . ALA A 1 247 ? 166.999 56.950 -60.252 1.00 15.08 ? 255 ALA A O 1 ATOM 2026 C CB . ALA A 1 247 ? 166.653 58.317 -63.036 1.00 16.16 ? 255 ALA A CB 1 ATOM 2027 N N . TYR A 1 248 ? 168.535 55.979 -61.550 1.00 16.19 ? 256 TYR A N 1 ATOM 2028 C CA . TYR A 1 248 ? 169.451 55.786 -60.434 1.00 15.72 ? 256 TYR A CA 1 ATOM 2029 C C . TYR A 1 248 ? 170.905 55.909 -60.876 1.00 15.75 ? 256 TYR A C 1 ATOM 2030 O O . TYR A 1 248 ? 171.805 55.321 -60.279 1.00 16.86 ? 256 TYR A O 1 ATOM 2031 C CB . TYR A 1 248 ? 169.204 54.458 -59.702 1.00 14.57 ? 256 TYR A CB 1 ATOM 2032 C CG . TYR A 1 248 ? 169.113 53.224 -60.556 1.00 15.99 ? 256 TYR A CG 1 ATOM 2033 C CD1 . TYR A 1 248 ? 170.232 52.705 -61.193 1.00 17.06 ? 256 TYR A CD1 1 ATOM 2034 C CD2 . TYR A 1 248 ? 167.897 52.569 -60.726 1.00 16.14 ? 256 TYR A CD2 1 ATOM 2035 C CE1 . TYR A 1 248 ? 170.141 51.555 -61.992 1.00 18.26 ? 256 TYR A CE1 1 ATOM 2036 C CE2 . TYR A 1 248 ? 167.793 51.429 -61.514 1.00 17.61 ? 256 TYR A CE2 1 ATOM 2037 C CZ . TYR A 1 248 ? 168.916 50.928 -62.150 1.00 18.27 ? 256 TYR A CZ 1 ATOM 2038 O OH . TYR A 1 248 ? 168.796 49.834 -62.979 1.00 18.08 ? 256 TYR A OH 1 ATOM 2039 N N . GLY A 1 249 ? 171.129 56.698 -61.923 1.00 15.22 ? 257 GLY A N 1 ATOM 2040 C CA . GLY A 1 249 ? 172.478 56.905 -62.418 1.00 15.89 ? 257 GLY A CA 1 ATOM 2041 C C . GLY A 1 249 ? 173.154 57.969 -61.573 1.00 18.60 ? 257 GLY A C 1 ATOM 2042 O O . GLY A 1 249 ? 172.475 58.737 -60.878 1.00 19.72 ? 257 GLY A O 1 ATOM 2043 N N . ARG A 1 250 ? 174.482 58.039 -61.628 1.00 19.35 ? 258 ARG A N 1 ATOM 2044 C CA . ARG A 1 250 ? 175.214 59.016 -60.830 1.00 19.05 ? 258 ARG A CA 1 ATOM 2045 C C . ARG A 1 250 ? 174.747 60.439 -61.085 1.00 18.99 ? 258 ARG A C 1 ATOM 2046 O O . ARG A 1 250 ? 174.659 60.881 -62.233 1.00 16.98 ? 258 ARG A O 1 ATOM 2047 C CB . ARG A 1 250 ? 176.702 58.914 -61.115 1.00 22.08 ? 258 ARG A CB 1 ATOM 2048 C CG . ARG A 1 250 ? 177.548 59.827 -60.254 1.00 25.93 ? 258 ARG A CG 1 ATOM 2049 C CD . ARG A 1 250 ? 178.991 59.373 -60.276 1.00 29.96 ? 258 ARG A CD 1 ATOM 2050 N NE . ARG A 1 250 ? 179.855 60.207 -59.446 1.00 36.09 ? 258 ARG A NE 1 ATOM 2051 C CZ . ARG A 1 250 ? 180.262 61.429 -59.779 1.00 39.08 ? 258 ARG A CZ 1 ATOM 2052 N NH1 . ARG A 1 250 ? 179.884 61.971 -60.933 1.00 40.95 ? 258 ARG A NH1 1 ATOM 2053 N NH2 . ARG A 1 250 ? 181.051 62.112 -58.958 1.00 41.52 ? 258 ARG A NH2 1 ATOM 2054 N N . GLY A 1 251 ? 174.441 61.152 -60.005 1.00 18.83 ? 259 GLY A N 1 ATOM 2055 C CA . GLY A 1 251 ? 173.993 62.526 -60.136 1.00 18.30 ? 259 GLY A CA 1 ATOM 2056 C C . GLY A 1 251 ? 172.488 62.711 -60.172 1.00 18.66 ? 259 GLY A C 1 ATOM 2057 O O . GLY A 1 251 ? 172.002 63.832 -60.007 1.00 19.81 ? 259 GLY A O 1 ATOM 2058 N N . THR A 1 252 ? 171.742 61.629 -60.381 1.00 18.04 ? 260 THR A N 1 ATOM 2059 C CA . THR A 1 252 ? 170.285 61.711 -60.432 1.00 18.22 ? 260 THR A CA 1 ATOM 2060 C C . THR A 1 252 ? 169.666 61.844 -59.048 1.00 18.69 ? 260 THR A C 1 ATOM 2061 O O . THR A 1 252 ? 170.303 61.548 -58.028 1.00 19.87 ? 260 THR A O 1 ATOM 2062 C CB . THR A 1 252 ? 169.677 60.467 -61.094 1.00 17.99 ? 260 THR A CB 1 ATOM 2063 O OG1 . THR A 1 252 ? 170.013 59.309 -60.322 1.00 17.62 ? 260 THR A OG1 1 ATOM 2064 C CG2 . THR A 1 252 ? 170.202 60.303 -62.508 1.00 18.40 ? 260 THR A CG2 1 ATOM 2065 N N . PRO A 1 253 ? 168.403 62.281 -58.992 1.00 18.33 ? 261 PRO A N 1 ATOM 2066 C CA . PRO A 1 253 ? 167.684 62.452 -57.725 1.00 19.50 ? 261 PRO A CA 1 ATOM 2067 C C . PRO A 1 253 ? 167.807 61.274 -56.757 1.00 18.40 ? 261 PRO A C 1 ATOM 2068 O O . PRO A 1 253 ? 168.246 61.450 -55.624 1.00 20.36 ? 261 PRO A O 1 ATOM 2069 C CB . PRO A 1 253 ? 166.248 62.677 -58.178 1.00 17.57 ? 261 PRO A CB 1 ATOM 2070 C CG . PRO A 1 253 ? 166.441 63.456 -59.435 1.00 19.44 ? 261 PRO A CG 1 ATOM 2071 C CD . PRO A 1 253 ? 167.568 62.708 -60.126 1.00 18.66 ? 261 PRO A CD 1 ATOM 2072 N N . GLN A 1 254 ? 167.423 60.080 -57.192 1.00 18.00 ? 262 GLN A N 1 ATOM 2073 C CA . GLN A 1 254 ? 167.499 58.919 -56.309 1.00 20.38 ? 262 GLN A CA 1 ATOM 2074 C C . GLN A 1 254 ? 168.917 58.619 -55.815 1.00 19.99 ? 262 GLN A C 1 ATOM 2075 O O . GLN A 1 254 ? 169.142 58.417 -54.620 1.00 19.55 ? 262 GLN A O 1 ATOM 2076 C CB . GLN A 1 254 ? 166.934 57.671 -56.993 1.00 20.11 ? 262 GLN A CB 1 ATOM 2077 C CG . GLN A 1 254 ? 166.789 56.504 -56.022 1.00 21.17 ? 262 GLN A CG 1 ATOM 2078 C CD . GLN A 1 254 ? 166.062 55.315 -56.613 1.00 22.58 ? 262 GLN A CD 1 ATOM 2079 O OE1 . GLN A 1 254 ? 165.668 54.398 -55.892 1.00 21.29 ? 262 GLN A OE1 1 ATOM 2080 N NE2 . GLN A 1 254 ? 165.880 55.321 -57.931 1.00 24.77 ? 262 GLN A NE2 1 ATOM 2081 N N . TYR A 1 255 ? 169.863 58.581 -56.745 1.00 19.57 ? 263 TYR A N 1 ATOM 2082 C CA . TYR A 1 255 ? 171.258 58.314 -56.428 1.00 19.78 ? 263 TYR A CA 1 ATOM 2083 C C . TYR A 1 255 ? 171.747 59.293 -55.354 1.00 20.03 ? 263 TYR A C 1 ATOM 2084 O O . TYR A 1 255 ? 172.289 58.891 -54.327 1.00 18.70 ? 263 TYR A O 1 ATOM 2085 C CB . TYR A 1 255 ? 172.079 58.447 -57.710 1.00 20.95 ? 263 TYR A CB 1 ATOM 2086 C CG . TYR A 1 255 ? 173.553 58.149 -57.571 1.00 22.22 ? 263 TYR A CG 1 ATOM 2087 C CD1 . TYR A 1 255 ? 174.431 59.089 -57.023 1.00 22.75 ? 263 TYR A CD1 1 ATOM 2088 C CD2 . TYR A 1 255 ? 174.078 56.942 -58.022 1.00 21.82 ? 263 TYR A CD2 1 ATOM 2089 C CE1 . TYR A 1 255 ? 175.792 58.836 -56.936 1.00 22.62 ? 263 TYR A CE1 1 ATOM 2090 C CE2 . TYR A 1 255 ? 175.436 56.678 -57.941 1.00 23.36 ? 263 TYR A CE2 1 ATOM 2091 C CZ . TYR A 1 255 ? 176.290 57.629 -57.397 1.00 24.23 ? 263 TYR A CZ 1 ATOM 2092 O OH . TYR A 1 255 ? 177.645 57.376 -57.322 1.00 26.52 ? 263 TYR A OH 1 ATOM 2093 N N . THR A 1 256 ? 171.539 60.580 -55.593 1.00 20.64 ? 264 THR A N 1 ATOM 2094 C CA . THR A 1 256 ? 171.937 61.604 -54.641 1.00 21.90 ? 264 THR A CA 1 ATOM 2095 C C . THR A 1 256 ? 171.299 61.385 -53.268 1.00 22.58 ? 264 THR A C 1 ATOM 2096 O O . THR A 1 256 ? 171.970 61.461 -52.236 1.00 24.81 ? 264 THR A O 1 ATOM 2097 C CB . THR A 1 256 ? 171.529 63.012 -55.141 1.00 22.53 ? 264 THR A CB 1 ATOM 2098 O OG1 . THR A 1 256 ? 172.208 63.300 -56.366 1.00 23.92 ? 264 THR A OG1 1 ATOM 2099 C CG2 . THR A 1 256 ? 171.903 64.080 -54.120 1.00 24.32 ? 264 THR A CG2 1 ATOM 2100 N N . TRP A 1 257 ? 170.001 61.120 -53.259 1.00 20.15 ? 265 TRP A N 1 ATOM 2101 C CA . TRP A 1 257 ? 169.283 60.914 -52.014 1.00 18.81 ? 265 TRP A CA 1 ATOM 2102 C C . TRP A 1 257 ? 169.833 59.738 -51.212 1.00 19.29 ? 265 TRP A C 1 ATOM 2103 O O . TRP A 1 257 ? 170.135 59.881 -50.031 1.00 19.62 ? 265 TRP A O 1 ATOM 2104 C CB . TRP A 1 257 ? 167.803 60.688 -52.313 1.00 19.60 ? 265 TRP A CB 1 ATOM 2105 C CG . TRP A 1 257 ? 166.966 60.475 -51.102 1.00 17.05 ? 265 TRP A CG 1 ATOM 2106 C CD1 . TRP A 1 257 ? 166.365 61.430 -50.338 1.00 15.98 ? 265 TRP A CD1 1 ATOM 2107 C CD2 . TRP A 1 257 ? 166.661 59.218 -50.495 1.00 17.85 ? 265 TRP A CD2 1 ATOM 2108 N NE1 . TRP A 1 257 ? 165.701 60.845 -49.284 1.00 14.90 ? 265 TRP A NE1 1 ATOM 2109 C CE2 . TRP A 1 257 ? 165.867 59.485 -49.356 1.00 17.06 ? 265 TRP A CE2 1 ATOM 2110 C CE3 . TRP A 1 257 ? 166.983 57.885 -50.804 1.00 18.29 ? 265 TRP A CE3 1 ATOM 2111 C CZ2 . TRP A 1 257 ? 165.382 58.461 -48.518 1.00 17.92 ? 265 TRP A CZ2 1 ATOM 2112 C CZ3 . TRP A 1 257 ? 166.500 56.862 -49.971 1.00 18.74 ? 265 TRP A CZ3 1 ATOM 2113 C CH2 . TRP A 1 257 ? 165.708 57.162 -48.840 1.00 17.27 ? 265 TRP A CH2 1 ATOM 2114 N N . LEU A 1 258 ? 169.966 58.580 -51.855 1.00 19.43 ? 266 LEU A N 1 ATOM 2115 C CA . LEU A 1 258 ? 170.466 57.378 -51.183 1.00 18.81 ? 266 LEU A CA 1 ATOM 2116 C C . LEU A 1 258 ? 171.841 57.591 -50.549 1.00 19.77 ? 266 LEU A C 1 ATOM 2117 O O . LEU A 1 258 ? 172.092 57.186 -49.407 1.00 17.98 ? 266 LEU A O 1 ATOM 2118 C CB . LEU A 1 258 ? 170.529 56.201 -52.172 1.00 15.32 ? 266 LEU A CB 1 ATOM 2119 C CG . LEU A 1 258 ? 170.943 54.846 -51.580 1.00 14.28 ? 266 LEU A CG 1 ATOM 2120 C CD1 . LEU A 1 258 ? 170.037 54.485 -50.402 1.00 13.15 ? 266 LEU A CD1 1 ATOM 2121 C CD2 . LEU A 1 258 ? 170.873 53.775 -52.651 1.00 11.87 ? 266 LEU A CD2 1 ATOM 2122 N N . LYS A 1 259 ? 172.733 58.224 -51.301 1.00 21.36 ? 267 LYS A N 1 ATOM 2123 C CA . LYS A 1 259 ? 174.079 58.489 -50.820 1.00 21.87 ? 267 LYS A CA 1 ATOM 2124 C C . LYS A 1 259 ? 174.021 59.296 -49.528 1.00 22.03 ? 267 LYS A C 1 ATOM 2125 O O . LYS A 1 259 ? 174.713 58.984 -48.566 1.00 21.41 ? 267 LYS A O 1 ATOM 2126 C CB . LYS A 1 259 ? 174.864 59.250 -51.878 1.00 23.28 ? 267 LYS A CB 1 ATOM 2127 C CG . LYS A 1 259 ? 176.347 59.320 -51.617 1.00 26.02 ? 267 LYS A CG 1 ATOM 2128 C CD . LYS A 1 259 ? 177.022 60.056 -52.751 1.00 30.67 ? 267 LYS A CD 1 ATOM 2129 C CE . LYS A 1 259 ? 178.524 60.071 -52.586 1.00 34.38 ? 267 LYS A CE 1 ATOM 2130 N NZ . LYS A 1 259 ? 179.144 60.867 -53.686 1.00 37.77 ? 267 LYS A NZ 1 ATOM 2131 N N . LYS A 1 260 ? 173.193 60.333 -49.503 1.00 22.57 ? 268 LYS A N 1 ATOM 2132 C CA . LYS A 1 260 ? 173.064 61.147 -48.306 1.00 24.22 ? 268 LYS A CA 1 ATOM 2133 C C . LYS A 1 260 ? 172.383 60.390 -47.169 1.00 23.81 ? 268 LYS A C 1 ATOM 2134 O O . LYS A 1 260 ? 172.840 60.426 -46.033 1.00 23.71 ? 268 LYS A O 1 ATOM 2135 C CB . LYS A 1 260 ? 172.269 62.419 -48.606 1.00 28.39 ? 268 LYS A CB 1 ATOM 2136 C CG . LYS A 1 260 ? 173.109 63.553 -49.166 1.00 36.50 ? 268 LYS A CG 1 ATOM 2137 C CD . LYS A 1 260 ? 172.284 64.834 -49.317 1.00 42.54 ? 268 LYS A CD 1 ATOM 2138 C CE . LYS A 1 260 ? 173.155 66.027 -49.736 1.00 45.85 ? 268 LYS A CE 1 ATOM 2139 N NZ . LYS A 1 260 ? 173.764 65.849 -51.093 1.00 48.89 ? 268 LYS A NZ 1 ATOM 2140 N N . GLU A 1 261 ? 171.292 59.699 -47.480 1.00 23.02 ? 269 GLU A N 1 ATOM 2141 C CA . GLU A 1 261 ? 170.542 58.962 -46.473 1.00 21.67 ? 269 GLU A CA 1 ATOM 2142 C C . GLU A 1 261 ? 171.372 57.937 -45.704 1.00 22.08 ? 269 GLU A C 1 ATOM 2143 O O . GLU A 1 261 ? 171.208 57.793 -44.493 1.00 23.04 ? 269 GLU A O 1 ATOM 2144 C CB . GLU A 1 261 ? 169.340 58.269 -47.118 1.00 20.12 ? 269 GLU A CB 1 ATOM 2145 C CG . GLU A 1 261 ? 168.346 57.687 -46.130 1.00 20.55 ? 269 GLU A CG 1 ATOM 2146 C CD . GLU A 1 261 ? 167.783 58.726 -45.171 1.00 21.82 ? 269 GLU A CD 1 ATOM 2147 O OE1 . GLU A 1 261 ? 167.771 59.930 -45.513 1.00 23.72 ? 269 GLU A OE1 1 ATOM 2148 O OE2 . GLU A 1 261 ? 167.334 58.332 -44.074 1.00 23.80 ? 269 GLU A OE2 1 ATOM 2149 N N . LEU A 1 262 ? 172.251 57.216 -46.390 1.00 21.66 ? 270 LEU A N 1 ATOM 2150 C CA . LEU A 1 262 ? 173.065 56.222 -45.709 1.00 22.47 ? 270 LEU A CA 1 ATOM 2151 C C . LEU A 1 262 ? 173.964 56.866 -44.660 1.00 25.84 ? 270 LEU A C 1 ATOM 2152 O O . LEU A 1 262 ? 174.202 56.281 -43.605 1.00 26.94 ? 270 LEU A O 1 ATOM 2153 C CB . LEU A 1 262 ? 173.899 55.433 -46.713 1.00 19.96 ? 270 LEU A CB 1 ATOM 2154 C CG . LEU A 1 262 ? 173.093 54.409 -47.515 1.00 17.57 ? 270 LEU A CG 1 ATOM 2155 C CD1 . LEU A 1 262 ? 173.957 53.855 -48.618 1.00 18.46 ? 270 LEU A CD1 1 ATOM 2156 C CD2 . LEU A 1 262 ? 172.600 53.292 -46.606 1.00 11.92 ? 270 LEU A CD2 1 ATOM 2157 N N . ARG A 1 263 ? 174.452 58.073 -44.940 1.00 28.11 ? 271 ARG A N 1 ATOM 2158 C CA . ARG A 1 263 ? 175.304 58.778 -43.988 1.00 30.96 ? 271 ARG A CA 1 ATOM 2159 C C . ARG A 1 263 ? 174.522 59.118 -42.729 1.00 30.82 ? 271 ARG A C 1 ATOM 2160 O O . ARG A 1 263 ? 175.080 59.147 -41.637 1.00 32.80 ? 271 ARG A O 1 ATOM 2161 C CB . ARG A 1 263 ? 175.847 60.085 -44.577 1.00 33.81 ? 271 ARG A CB 1 ATOM 2162 C CG . ARG A 1 263 ? 177.003 59.941 -45.550 1.00 39.09 ? 271 ARG A CG 1 ATOM 2163 C CD . ARG A 1 263 ? 177.609 61.319 -45.867 1.00 45.38 ? 271 ARG A CD 1 ATOM 2164 N NE . ARG A 1 263 ? 178.703 61.238 -46.838 1.00 51.83 ? 271 ARG A NE 1 ATOM 2165 C CZ . ARG A 1 263 ? 178.571 61.440 -48.149 1.00 52.90 ? 271 ARG A CZ 1 ATOM 2166 N NH1 . ARG A 1 263 ? 177.384 61.750 -48.663 1.00 52.71 ? 271 ARG A NH1 1 ATOM 2167 N NH2 . ARG A 1 263 ? 179.622 61.315 -48.954 1.00 52.86 ? 271 ARG A NH2 1 ATOM 2168 N N . LYS A 1 264 ? 173.228 59.373 -42.880 1.00 30.49 ? 272 LYS A N 1 ATOM 2169 C CA . LYS A 1 264 ? 172.394 59.738 -41.744 1.00 29.73 ? 272 LYS A CA 1 ATOM 2170 C C . LYS A 1 264 ? 171.913 58.573 -40.893 1.00 29.34 ? 272 LYS A C 1 ATOM 2171 O O . LYS A 1 264 ? 171.269 58.782 -39.870 1.00 30.74 ? 272 LYS A O 1 ATOM 2172 C CB . LYS A 1 264 ? 171.191 60.560 -42.215 1.00 30.16 ? 272 LYS A CB 1 ATOM 2173 C CG . LYS A 1 264 ? 171.583 61.863 -42.903 1.00 35.35 ? 272 LYS A CG 1 ATOM 2174 C CD . LYS A 1 264 ? 170.432 62.868 -42.947 1.00 39.16 ? 272 LYS A CD 1 ATOM 2175 C CE . LYS A 1 264 ? 169.267 62.369 -43.784 1.00 43.10 ? 272 LYS A CE 1 ATOM 2176 N NZ . LYS A 1 264 ? 168.151 63.363 -43.836 1.00 46.81 ? 272 LYS A NZ 1 ATOM 2177 N N . VAL A 1 265 ? 172.213 57.346 -41.296 1.00 28.38 ? 273 VAL A N 1 ATOM 2178 C CA . VAL A 1 265 ? 171.780 56.204 -40.499 1.00 28.44 ? 273 VAL A CA 1 ATOM 2179 C C . VAL A 1 265 ? 172.612 56.119 -39.221 1.00 29.25 ? 273 VAL A C 1 ATOM 2180 O O . VAL A 1 265 ? 173.838 56.189 -39.273 1.00 29.31 ? 273 VAL A O 1 ATOM 2181 C CB . VAL A 1 265 ? 171.929 54.867 -41.269 1.00 26.80 ? 273 VAL A CB 1 ATOM 2182 C CG1 . VAL A 1 265 ? 171.467 53.713 -40.389 1.00 23.30 ? 273 VAL A CG1 1 ATOM 2183 C CG2 . VAL A 1 265 ? 171.123 54.906 -42.555 1.00 23.53 ? 273 VAL A CG2 1 ATOM 2184 N N . LYS A 1 266 ? 171.940 55.988 -38.079 1.00 30.37 ? 274 LYS A N 1 ATOM 2185 C CA . LYS A 1 266 ? 172.619 55.870 -36.787 1.00 31.24 ? 274 LYS A CA 1 ATOM 2186 C C . LYS A 1 266 ? 172.316 54.497 -36.193 1.00 29.77 ? 274 LYS A C 1 ATOM 2187 O O . LYS A 1 266 ? 171.213 54.264 -35.697 1.00 28.88 ? 274 LYS A O 1 ATOM 2188 C CB . LYS A 1 266 ? 172.128 56.948 -35.821 1.00 34.52 ? 274 LYS A CB 1 ATOM 2189 C CG . LYS A 1 266 ? 172.758 58.315 -36.014 1.00 40.81 ? 274 LYS A CG 1 ATOM 2190 C CD . LYS A 1 266 ? 172.083 59.341 -35.113 1.00 47.60 ? 274 LYS A CD 1 ATOM 2191 C CE . LYS A 1 266 ? 172.068 58.883 -33.649 1.00 51.65 ? 274 LYS A CE 1 ATOM 2192 N NZ . LYS A 1 266 ? 171.336 59.834 -32.754 1.00 53.61 ? 274 LYS A NZ 1 ATOM 2193 N N . ARG A 1 267 ? 173.287 53.592 -36.244 1.00 28.88 ? 275 ARG A N 1 ATOM 2194 C CA . ARG A 1 267 ? 173.081 52.251 -35.713 1.00 29.38 ? 275 ARG A CA 1 ATOM 2195 C C . ARG A 1 267 ? 172.942 52.231 -34.202 1.00 29.84 ? 275 ARG A C 1 ATOM 2196 O O . ARG A 1 267 ? 172.518 51.233 -33.621 1.00 28.58 ? 275 ARG A O 1 ATOM 2197 C CB . ARG A 1 267 ? 174.218 51.340 -36.138 1.00 28.20 ? 275 ARG A CB 1 ATOM 2198 C CG . ARG A 1 267 ? 174.295 51.187 -37.627 1.00 27.74 ? 275 ARG A CG 1 ATOM 2199 C CD . ARG A 1 267 ? 173.035 50.572 -38.214 1.00 26.02 ? 275 ARG A CD 1 ATOM 2200 N NE . ARG A 1 267 ? 173.441 49.804 -39.378 1.00 29.87 ? 275 ARG A NE 1 ATOM 2201 C CZ . ARG A 1 267 ? 173.544 48.482 -39.410 1.00 29.15 ? 275 ARG A CZ 1 ATOM 2202 N NH1 . ARG A 1 267 ? 173.246 47.761 -38.349 1.00 31.50 ? 275 ARG A NH1 1 ATOM 2203 N NH2 . ARG A 1 267 ? 174.007 47.887 -40.489 1.00 31.80 ? 275 ARG A NH2 1 ATOM 2204 N N . SER A 1 268 ? 173.309 53.341 -33.575 1.00 31.09 ? 276 SER A N 1 ATOM 2205 C CA . SER A 1 268 ? 173.206 53.485 -32.133 1.00 32.85 ? 276 SER A CA 1 ATOM 2206 C C . SER A 1 268 ? 171.754 53.783 -31.757 1.00 33.06 ? 276 SER A C 1 ATOM 2207 O O . SER A 1 268 ? 171.307 53.445 -30.665 1.00 33.57 ? 276 SER A O 1 ATOM 2208 C CB . SER A 1 268 ? 174.112 54.619 -31.669 1.00 33.01 ? 276 SER A CB 1 ATOM 2209 O OG . SER A 1 268 ? 174.042 55.696 -32.589 1.00 38.14 ? 276 SER A OG 1 ATOM 2210 N N . GLU A 1 269 ? 171.019 54.412 -32.670 1.00 33.61 ? 277 GLU A N 1 ATOM 2211 C CA . GLU A 1 269 ? 169.621 54.744 -32.432 1.00 33.87 ? 277 GLU A CA 1 ATOM 2212 C C . GLU A 1 269 ? 168.725 53.641 -33.008 1.00 32.61 ? 277 GLU A C 1 ATOM 2213 O O . GLU A 1 269 ? 167.826 53.137 -32.334 1.00 32.31 ? 277 GLU A O 1 ATOM 2214 C CB . GLU A 1 269 ? 169.281 56.088 -33.085 1.00 38.09 ? 277 GLU A CB 1 ATOM 2215 C CG . GLU A 1 269 ? 167.880 56.606 -32.759 1.00 46.56 ? 277 GLU A CG 1 ATOM 2216 C CD . GLU A 1 269 ? 167.523 57.885 -33.519 1.00 51.91 ? 277 GLU A CD 1 ATOM 2217 O OE1 . GLU A 1 269 ? 168.383 58.793 -33.584 1.00 55.43 ? 277 GLU A OE1 1 ATOM 2218 O OE2 . GLU A 1 269 ? 166.387 57.986 -34.045 1.00 52.77 ? 277 GLU A OE2 1 ATOM 2219 N N . THR A 1 270 ? 168.976 53.274 -34.263 1.00 30.49 ? 278 THR A N 1 ATOM 2220 C CA . THR A 1 270 ? 168.213 52.228 -34.945 1.00 27.24 ? 278 THR A CA 1 ATOM 2221 C C . THR A 1 270 ? 169.224 51.205 -35.454 1.00 25.83 ? 278 THR A C 1 ATOM 2222 O O . THR A 1 270 ? 169.781 51.355 -36.541 1.00 26.15 ? 278 THR A O 1 ATOM 2223 C CB . THR A 1 270 ? 167.428 52.804 -36.139 1.00 26.02 ? 278 THR A CB 1 ATOM 2224 O OG1 . THR A 1 270 ? 168.319 53.547 -36.981 1.00 25.63 ? 278 THR A OG1 1 ATOM 2225 C CG2 . THR A 1 270 ? 166.315 53.726 -35.654 1.00 25.98 ? 278 THR A CG2 1 ATOM 2226 N N . PRO A 1 271 ? 169.475 50.148 -34.671 1.00 23.50 ? 279 PRO A N 1 ATOM 2227 C CA . PRO A 1 271 ? 170.429 49.101 -35.037 1.00 23.18 ? 279 PRO A CA 1 ATOM 2228 C C . PRO A 1 271 ? 170.150 48.343 -36.332 1.00 23.26 ? 279 PRO A C 1 ATOM 2229 O O . PRO A 1 271 ? 171.076 48.015 -37.079 1.00 24.32 ? 279 PRO A O 1 ATOM 2230 C CB . PRO A 1 271 ? 170.415 48.190 -33.815 1.00 22.15 ? 279 PRO A CB 1 ATOM 2231 C CG . PRO A 1 271 ? 169.028 48.328 -33.330 1.00 23.08 ? 279 PRO A CG 1 ATOM 2232 C CD . PRO A 1 271 ? 168.791 49.804 -33.416 1.00 22.57 ? 279 PRO A CD 1 ATOM 2233 N N . TRP A 1 272 ? 168.881 48.068 -36.604 1.00 22.26 ? 280 TRP A N 1 ATOM 2234 C CA . TRP A 1 272 ? 168.526 47.318 -37.798 1.00 20.24 ? 280 TRP A CA 1 ATOM 2235 C C . TRP A 1 272 ? 168.357 48.180 -39.036 1.00 19.78 ? 280 TRP A C 1 ATOM 2236 O O . TRP A 1 272 ? 167.485 49.057 -39.078 1.00 20.08 ? 280 TRP A O 1 ATOM 2237 C CB . TRP A 1 272 ? 167.260 46.512 -37.528 1.00 19.70 ? 280 TRP A CB 1 ATOM 2238 C CG . TRP A 1 272 ? 167.478 45.546 -36.415 1.00 19.27 ? 280 TRP A CG 1 ATOM 2239 C CD1 . TRP A 1 272 ? 167.166 45.721 -35.091 1.00 18.82 ? 280 TRP A CD1 1 ATOM 2240 C CD2 . TRP A 1 272 ? 168.174 44.300 -36.503 1.00 19.28 ? 280 TRP A CD2 1 ATOM 2241 N NE1 . TRP A 1 272 ? 167.632 44.657 -34.352 1.00 19.43 ? 280 TRP A NE1 1 ATOM 2242 C CE2 . TRP A 1 272 ? 168.255 43.770 -35.194 1.00 19.58 ? 280 TRP A CE2 1 ATOM 2243 C CE3 . TRP A 1 272 ? 168.742 43.578 -37.564 1.00 18.14 ? 280 TRP A CE3 1 ATOM 2244 C CZ2 . TRP A 1 272 ? 168.883 42.552 -34.918 1.00 19.87 ? 280 TRP A CZ2 1 ATOM 2245 C CZ3 . TRP A 1 272 ? 169.366 42.368 -37.293 1.00 18.32 ? 280 TRP A CZ3 1 ATOM 2246 C CH2 . TRP A 1 272 ? 169.432 41.866 -35.978 1.00 20.37 ? 280 TRP A CH2 1 ATOM 2247 N N . LEU A 1 273 ? 169.208 47.934 -40.034 1.00 18.02 ? 281 LEU A N 1 ATOM 2248 C CA . LEU A 1 273 ? 169.166 48.681 -41.286 1.00 18.24 ? 281 LEU A CA 1 ATOM 2249 C C . LEU A 1 273 ? 168.639 47.783 -42.395 1.00 18.69 ? 281 LEU A C 1 ATOM 2250 O O . LEU A 1 273 ? 169.324 46.840 -42.834 1.00 18.13 ? 281 LEU A O 1 ATOM 2251 C CB . LEU A 1 273 ? 170.557 49.201 -41.652 1.00 16.61 ? 281 LEU A CB 1 ATOM 2252 C CG . LEU A 1 273 ? 170.600 50.017 -42.948 1.00 16.21 ? 281 LEU A CG 1 ATOM 2253 C CD1 . LEU A 1 273 ? 169.552 51.131 -42.895 1.00 15.30 ? 281 LEU A CD1 1 ATOM 2254 C CD2 . LEU A 1 273 ? 171.987 50.601 -43.143 1.00 14.39 ? 281 LEU A CD2 1 ATOM 2255 N N . ILE A 1 274 ? 167.424 48.099 -42.843 1.00 17.75 ? 282 ILE A N 1 ATOM 2256 C CA . ILE A 1 274 ? 166.729 47.336 -43.872 1.00 17.27 ? 282 ILE A CA 1 ATOM 2257 C C . ILE A 1 274 ? 166.503 48.138 -45.158 1.00 17.02 ? 282 ILE A C 1 ATOM 2258 O O . ILE A 1 274 ? 166.197 49.339 -45.105 1.00 17.40 ? 282 ILE A O 1 ATOM 2259 C CB . ILE A 1 274 ? 165.347 46.876 -43.338 1.00 18.05 ? 282 ILE A CB 1 ATOM 2260 C CG1 . ILE A 1 274 ? 165.527 46.125 -42.018 1.00 16.74 ? 282 ILE A CG1 1 ATOM 2261 C CG2 . ILE A 1 274 ? 164.643 45.985 -44.358 1.00 18.35 ? 282 ILE A CG2 1 ATOM 2262 C CD1 . ILE A 1 274 ? 164.227 45.647 -41.417 1.00 18.22 ? 282 ILE A CD1 1 ATOM 2263 N N . VAL A 1 275 ? 166.643 47.470 -46.306 1.00 16.11 ? 283 VAL A N 1 ATOM 2264 C CA . VAL A 1 275 ? 166.430 48.102 -47.610 1.00 15.56 ? 283 VAL A CA 1 ATOM 2265 C C . VAL A 1 275 ? 165.365 47.332 -48.390 1.00 15.60 ? 283 VAL A C 1 ATOM 2266 O O . VAL A 1 275 ? 165.377 46.099 -48.419 1.00 15.63 ? 283 VAL A O 1 ATOM 2267 C CB . VAL A 1 275 ? 167.718 48.110 -48.467 1.00 15.00 ? 283 VAL A CB 1 ATOM 2268 C CG1 . VAL A 1 275 ? 167.436 48.739 -49.835 1.00 11.10 ? 283 VAL A CG1 1 ATOM 2269 C CG2 . VAL A 1 275 ? 168.817 48.874 -47.754 1.00 13.39 ? 283 VAL A CG2 1 ATOM 2270 N N . LEU A 1 276 ? 164.448 48.060 -49.021 1.00 15.37 ? 284 LEU A N 1 ATOM 2271 C CA . LEU A 1 276 ? 163.387 47.446 -49.823 1.00 14.58 ? 284 LEU A CA 1 ATOM 2272 C C . LEU A 1 276 ? 163.495 47.936 -51.257 1.00 13.47 ? 284 LEU A C 1 ATOM 2273 O O . LEU A 1 276 ? 163.769 49.111 -51.497 1.00 13.27 ? 284 LEU A O 1 ATOM 2274 C CB . LEU A 1 276 ? 162.005 47.832 -49.295 1.00 14.30 ? 284 LEU A CB 1 ATOM 2275 C CG . LEU A 1 276 ? 161.657 47.591 -47.831 1.00 16.43 ? 284 LEU A CG 1 ATOM 2276 C CD1 . LEU A 1 276 ? 160.226 48.042 -47.597 1.00 16.59 ? 284 LEU A CD1 1 ATOM 2277 C CD2 . LEU A 1 276 ? 161.821 46.120 -47.469 1.00 16.31 ? 284 LEU A CD2 1 ATOM 2278 N N . MET A 1 277 ? 163.270 47.034 -52.204 1.00 14.26 ? 285 MET A N 1 ATOM 2279 C CA . MET A 1 277 ? 163.310 47.358 -53.632 1.00 15.16 ? 285 MET A CA 1 ATOM 2280 C C . MET A 1 277 ? 162.518 46.254 -54.311 1.00 15.98 ? 285 MET A C 1 ATOM 2281 O O . MET A 1 277 ? 162.431 45.145 -53.783 1.00 17.70 ? 285 MET A O 1 ATOM 2282 C CB . MET A 1 277 ? 164.752 47.361 -54.143 1.00 13.42 ? 285 MET A CB 1 ATOM 2283 C CG . MET A 1 277 ? 165.485 46.080 -53.856 1.00 13.93 ? 285 MET A CG 1 ATOM 2284 S SD . MET A 1 277 ? 167.142 46.101 -54.525 1.00 17.81 ? 285 MET A SD 1 ATOM 2285 C CE . MET A 1 277 ? 167.985 47.133 -53.319 1.00 13.14 ? 285 MET A CE 1 ATOM 2286 N N . HIS A 1 278 ? 161.931 46.527 -55.468 1.00 16.03 ? 286 HIS A N 1 ATOM 2287 C CA . HIS A 1 278 ? 161.167 45.474 -56.109 1.00 15.19 ? 286 HIS A CA 1 ATOM 2288 C C . HIS A 1 278 ? 162.020 44.390 -56.774 1.00 14.68 ? 286 HIS A C 1 ATOM 2289 O O . HIS A 1 278 ? 161.776 43.211 -56.558 1.00 14.94 ? 286 HIS A O 1 ATOM 2290 C CB . HIS A 1 278 ? 160.190 46.050 -57.130 1.00 14.89 ? 286 HIS A CB 1 ATOM 2291 C CG . HIS A 1 278 ? 159.301 45.014 -57.742 1.00 15.75 ? 286 HIS A CG 1 ATOM 2292 N ND1 . HIS A 1 278 ? 158.344 44.335 -57.017 1.00 14.86 ? 286 HIS A ND1 1 ATOM 2293 C CD2 . HIS A 1 278 ? 159.263 44.498 -58.994 1.00 14.83 ? 286 HIS A CD2 1 ATOM 2294 C CE1 . HIS A 1 278 ? 157.757 43.444 -57.797 1.00 15.70 ? 286 HIS A CE1 1 ATOM 2295 N NE2 . HIS A 1 278 ? 158.297 43.522 -59.001 1.00 15.71 ? 286 HIS A NE2 1 ATOM 2296 N N . SER A 1 279 ? 163.025 44.777 -57.559 1.00 14.87 ? 287 SER A N 1 ATOM 2297 C CA . SER A 1 279 ? 163.856 43.795 -58.264 1.00 15.83 ? 287 SER A CA 1 ATOM 2298 C C . SER A 1 279 ? 165.087 43.306 -57.489 1.00 15.65 ? 287 SER A C 1 ATOM 2299 O O . SER A 1 279 ? 165.993 44.083 -57.195 1.00 17.49 ? 287 SER A O 1 ATOM 2300 C CB . SER A 1 279 ? 164.302 44.372 -59.606 1.00 16.29 ? 287 SER A CB 1 ATOM 2301 O OG . SER A 1 279 ? 164.891 43.366 -60.403 1.00 20.01 ? 287 SER A OG 1 ATOM 2302 N N . PRO A 1 280 ? 165.149 41.997 -57.181 1.00 15.94 ? 288 PRO A N 1 ATOM 2303 C CA . PRO A 1 280 ? 166.266 41.395 -56.437 1.00 15.04 ? 288 PRO A CA 1 ATOM 2304 C C . PRO A 1 280 ? 167.636 41.528 -57.107 1.00 16.76 ? 288 PRO A C 1 ATOM 2305 O O . PRO A 1 280 ? 167.768 41.279 -58.310 1.00 16.80 ? 288 PRO A O 1 ATOM 2306 C CB . PRO A 1 280 ? 165.837 39.942 -56.303 1.00 14.16 ? 288 PRO A CB 1 ATOM 2307 C CG . PRO A 1 280 ? 165.084 39.704 -57.601 1.00 13.85 ? 288 PRO A CG 1 ATOM 2308 C CD . PRO A 1 280 ? 164.235 40.954 -57.693 1.00 14.55 ? 288 PRO A CD 1 ATOM 2309 N N . LEU A 1 281 ? 168.647 41.916 -56.324 1.00 16.66 ? 289 LEU A N 1 ATOM 2310 C CA . LEU A 1 281 ? 170.004 42.082 -56.839 1.00 16.81 ? 289 LEU A CA 1 ATOM 2311 C C . LEU A 1 281 ? 170.668 40.710 -56.985 1.00 17.63 ? 289 LEU A C 1 ATOM 2312 O O . LEU A 1 281 ? 171.574 40.525 -57.801 1.00 17.61 ? 289 LEU A O 1 ATOM 2313 C CB . LEU A 1 281 ? 170.825 42.973 -55.905 1.00 15.84 ? 289 LEU A CB 1 ATOM 2314 C CG . LEU A 1 281 ? 170.272 44.373 -55.605 1.00 17.32 ? 289 LEU A CG 1 ATOM 2315 C CD1 . LEU A 1 281 ? 171.298 45.167 -54.795 1.00 15.99 ? 289 LEU A CD1 1 ATOM 2316 C CD2 . LEU A 1 281 ? 169.942 45.103 -56.902 1.00 15.73 ? 289 LEU A CD2 1 ATOM 2317 N N . TYR A 1 282 ? 170.232 39.758 -56.168 1.00 16.76 ? 290 TYR A N 1 ATOM 2318 C CA . TYR A 1 282 ? 170.732 38.392 -56.257 1.00 17.93 ? 290 TYR A CA 1 ATOM 2319 C C . TYR A 1 282 ? 169.508 37.534 -56.490 1.00 19.89 ? 290 TYR A C 1 ATOM 2320 O O . TYR A 1 282 ? 168.496 37.675 -55.796 1.00 19.85 ? 290 TYR A O 1 ATOM 2321 C CB . TYR A 1 282 ? 171.452 37.978 -54.985 1.00 17.28 ? 290 TYR A CB 1 ATOM 2322 C CG . TYR A 1 282 ? 172.879 38.462 -54.953 1.00 15.21 ? 290 TYR A CG 1 ATOM 2323 C CD1 . TYR A 1 282 ? 173.924 37.641 -55.371 1.00 15.46 ? 290 TYR A CD1 1 ATOM 2324 C CD2 . TYR A 1 282 ? 173.179 39.757 -54.546 1.00 14.11 ? 290 TYR A CD2 1 ATOM 2325 C CE1 . TYR A 1 282 ? 175.236 38.101 -55.384 1.00 16.09 ? 290 TYR A CE1 1 ATOM 2326 C CE2 . TYR A 1 282 ? 174.482 40.228 -54.554 1.00 15.85 ? 290 TYR A CE2 1 ATOM 2327 C CZ . TYR A 1 282 ? 175.505 39.398 -54.972 1.00 17.18 ? 290 TYR A CZ 1 ATOM 2328 O OH . TYR A 1 282 ? 176.799 39.873 -54.957 1.00 18.43 ? 290 TYR A OH 1 ATOM 2329 N N . ASN A 1 283 ? 169.598 36.662 -57.489 1.00 20.12 ? 291 ASN A N 1 ATOM 2330 C CA . ASN A 1 283 ? 168.479 35.817 -57.857 1.00 20.09 ? 291 ASN A CA 1 ATOM 2331 C C . ASN A 1 283 ? 168.946 34.623 -58.677 1.00 20.48 ? 291 ASN A C 1 ATOM 2332 O O . ASN A 1 283 ? 169.585 34.790 -59.717 1.00 18.26 ? 291 ASN A O 1 ATOM 2333 C CB . ASN A 1 283 ? 167.501 36.639 -58.685 1.00 20.46 ? 291 ASN A CB 1 ATOM 2334 C CG . ASN A 1 283 ? 166.410 35.801 -59.289 1.00 22.53 ? 291 ASN A CG 1 ATOM 2335 O OD1 . ASN A 1 283 ? 165.820 36.182 -60.294 1.00 25.83 ? 291 ASN A OD1 1 ATOM 2336 N ND2 . ASN A 1 283 ? 166.125 34.655 -58.678 1.00 24.69 ? 291 ASN A ND2 1 ATOM 2337 N N . SER A 1 284 ? 168.614 33.419 -58.223 1.00 20.52 ? 292 SER A N 1 ATOM 2338 C CA . SER A 1 284 ? 169.023 32.233 -58.959 1.00 21.95 ? 292 SER A CA 1 ATOM 2339 C C . SER A 1 284 ? 167.875 31.563 -59.715 1.00 22.95 ? 292 SER A C 1 ATOM 2340 O O . SER A 1 284 ? 167.975 30.391 -60.083 1.00 23.06 ? 292 SER A O 1 ATOM 2341 C CB . SER A 1 284 ? 169.705 31.227 -58.023 1.00 21.34 ? 292 SER A CB 1 ATOM 2342 O OG . SER A 1 284 ? 168.820 30.770 -57.020 1.00 21.15 ? 292 SER A OG 1 ATOM 2343 N N . TYR A 1 285 ? 166.780 32.291 -59.932 1.00 22.41 ? 293 TYR A N 1 ATOM 2344 C CA . TYR A 1 285 ? 165.656 31.741 -60.690 1.00 22.22 ? 293 TYR A CA 1 ATOM 2345 C C . TYR A 1 285 ? 165.826 32.211 -62.123 1.00 23.51 ? 293 TYR A C 1 ATOM 2346 O O . TYR A 1 285 ? 166.438 33.253 -62.364 1.00 22.39 ? 293 TYR A O 1 ATOM 2347 C CB . TYR A 1 285 ? 164.314 32.241 -60.161 1.00 21.02 ? 293 TYR A CB 1 ATOM 2348 C CG . TYR A 1 285 ? 163.871 31.567 -58.892 1.00 20.66 ? 293 TYR A CG 1 ATOM 2349 C CD1 . TYR A 1 285 ? 164.466 31.877 -57.675 1.00 19.68 ? 293 TYR A CD1 1 ATOM 2350 C CD2 . TYR A 1 285 ? 162.867 30.599 -58.909 1.00 19.81 ? 293 TYR A CD2 1 ATOM 2351 C CE1 . TYR A 1 285 ? 164.072 31.243 -56.499 1.00 19.44 ? 293 TYR A CE1 1 ATOM 2352 C CE2 . TYR A 1 285 ? 162.466 29.959 -57.740 1.00 18.27 ? 293 TYR A CE2 1 ATOM 2353 C CZ . TYR A 1 285 ? 163.072 30.288 -56.539 1.00 18.96 ? 293 TYR A CZ 1 ATOM 2354 O OH . TYR A 1 285 ? 162.662 29.692 -55.369 1.00 19.33 ? 293 TYR A OH 1 ATOM 2355 N N . ASN A 1 286 ? 165.296 31.448 -63.075 1.00 25.12 ? 294 ASN A N 1 ATOM 2356 C CA . ASN A 1 286 ? 165.416 31.824 -64.478 1.00 26.49 ? 294 ASN A CA 1 ATOM 2357 C C . ASN A 1 286 ? 164.602 33.064 -64.773 1.00 25.47 ? 294 ASN A C 1 ATOM 2358 O O . ASN A 1 286 ? 165.054 33.959 -65.485 1.00 25.34 ? 294 ASN A O 1 ATOM 2359 C CB . ASN A 1 286 ? 164.947 30.695 -65.394 1.00 30.93 ? 294 ASN A CB 1 ATOM 2360 C CG . ASN A 1 286 ? 165.938 29.549 -65.460 1.00 37.10 ? 294 ASN A CG 1 ATOM 2361 O OD1 . ASN A 1 286 ? 167.105 29.741 -65.816 1.00 38.83 ? 294 ASN A OD1 1 ATOM 2362 N ND2 . ASN A 1 286 ? 165.477 28.341 -65.116 1.00 40.15 ? 294 ASN A ND2 1 ATOM 2363 N N . HIS A 1 287 ? 163.396 33.123 -64.227 1.00 25.42 ? 295 HIS A N 1 ATOM 2364 C CA . HIS A 1 287 ? 162.541 34.276 -64.469 1.00 26.09 ? 295 HIS A CA 1 ATOM 2365 C C . HIS A 1 287 ? 163.163 35.551 -63.894 1.00 24.57 ? 295 HIS A C 1 ATOM 2366 O O . HIS A 1 287 ? 163.387 35.652 -62.687 1.00 25.64 ? 295 HIS A O 1 ATOM 2367 C CB . HIS A 1 287 ? 161.154 34.060 -63.859 1.00 25.42 ? 295 HIS A CB 1 ATOM 2368 C CG . HIS A 1 287 ? 160.110 34.962 -64.436 1.00 28.97 ? 295 HIS A CG 1 ATOM 2369 N ND1 . HIS A 1 287 ? 158.916 35.233 -63.799 1.00 31.63 ? 295 HIS A ND1 1 ATOM 2370 C CD2 . HIS A 1 287 ? 160.079 35.656 -65.601 1.00 28.97 ? 295 HIS A CD2 1 ATOM 2371 C CE1 . HIS A 1 287 ? 158.198 36.054 -64.546 1.00 30.84 ? 295 HIS A CE1 1 ATOM 2372 N NE2 . HIS A 1 287 ? 158.880 36.326 -65.646 1.00 28.41 ? 295 HIS A NE2 1 ATOM 2373 N N . HIS A 1 288 ? 163.450 36.515 -64.767 1.00 22.93 ? 296 HIS A N 1 ATOM 2374 C CA . HIS A 1 288 ? 164.035 37.798 -64.362 1.00 21.78 ? 296 HIS A CA 1 ATOM 2375 C C . HIS A 1 288 ? 165.480 37.683 -63.912 1.00 20.54 ? 296 HIS A C 1 ATOM 2376 O O . HIS A 1 288 ? 165.971 38.526 -63.174 1.00 20.12 ? 296 HIS A O 1 ATOM 2377 C CB . HIS A 1 288 ? 163.226 38.435 -63.232 1.00 20.33 ? 296 HIS A CB 1 ATOM 2378 C CG . HIS A 1 288 ? 161.803 38.714 -63.591 1.00 19.05 ? 296 HIS A CG 1 ATOM 2379 N ND1 . HIS A 1 288 ? 161.446 39.491 -64.671 1.00 19.74 ? 296 HIS A ND1 1 ATOM 2380 C CD2 . HIS A 1 288 ? 160.645 38.318 -63.013 1.00 20.03 ? 296 HIS A CD2 1 ATOM 2381 C CE1 . HIS A 1 288 ? 160.129 39.563 -64.745 1.00 20.02 ? 296 HIS A CE1 1 ATOM 2382 N NE2 . HIS A 1 288 ? 159.619 38.859 -63.750 1.00 20.77 ? 296 HIS A NE2 1 ATOM 2383 N N . PHE A 1 289 ? 166.158 36.641 -64.365 1.00 19.50 ? 297 PHE A N 1 ATOM 2384 C CA . PHE A 1 289 ? 167.545 36.423 -64.005 1.00 18.24 ? 297 PHE A CA 1 ATOM 2385 C C . PHE A 1 289 ? 168.396 37.598 -64.474 1.00 19.04 ? 297 PHE A C 1 ATOM 2386 O O . PHE A 1 289 ? 168.256 38.070 -65.600 1.00 19.88 ? 297 PHE A O 1 ATOM 2387 C CB . PHE A 1 289 ? 168.026 35.127 -64.651 1.00 16.70 ? 297 PHE A CB 1 ATOM 2388 C CG . PHE A 1 289 ? 169.432 34.759 -64.305 1.00 15.38 ? 297 PHE A CG 1 ATOM 2389 C CD1 . PHE A 1 289 ? 169.805 34.545 -62.986 1.00 18.18 ? 297 PHE A CD1 1 ATOM 2390 C CD2 . PHE A 1 289 ? 170.380 34.595 -65.303 1.00 14.68 ? 297 PHE A CD2 1 ATOM 2391 C CE1 . PHE A 1 289 ? 171.112 34.167 -62.667 1.00 17.76 ? 297 PHE A CE1 1 ATOM 2392 C CE2 . PHE A 1 289 ? 171.681 34.220 -64.999 1.00 15.42 ? 297 PHE A CE2 1 ATOM 2393 C CZ . PHE A 1 289 ? 172.052 34.005 -63.681 1.00 17.15 ? 297 PHE A CZ 1 ATOM 2394 N N . MET A 1 290 ? 169.275 38.066 -63.595 1.00 18.89 ? 298 MET A N 1 ATOM 2395 C CA . MET A 1 290 ? 170.176 39.180 -63.885 1.00 18.00 ? 298 MET A CA 1 ATOM 2396 C C . MET A 1 290 ? 169.532 40.535 -64.190 1.00 17.81 ? 298 MET A C 1 ATOM 2397 O O . MET A 1 290 ? 170.203 41.440 -64.677 1.00 18.55 ? 298 MET A O 1 ATOM 2398 C CB . MET A 1 290 ? 171.129 38.815 -65.026 1.00 16.90 ? 298 MET A CB 1 ATOM 2399 C CG . MET A 1 290 ? 172.063 37.656 -64.709 1.00 19.03 ? 298 MET A CG 1 ATOM 2400 S SD . MET A 1 290 ? 173.491 37.641 -65.817 1.00 22.59 ? 298 MET A SD 1 ATOM 2401 C CE . MET A 1 290 ? 172.708 37.087 -67.371 1.00 26.52 ? 298 MET A CE 1 ATOM 2402 N N . GLU A 1 291 ? 168.245 40.692 -63.905 1.00 17.22 ? 299 GLU A N 1 ATOM 2403 C CA . GLU A 1 291 ? 167.598 41.972 -64.167 1.00 17.36 ? 299 GLU A CA 1 ATOM 2404 C C . GLU A 1 291 ? 168.109 43.010 -63.187 1.00 17.17 ? 299 GLU A C 1 ATOM 2405 O O . GLU A 1 291 ? 168.151 44.204 -63.497 1.00 17.09 ? 299 GLU A O 1 ATOM 2406 C CB . GLU A 1 291 ? 166.082 41.852 -64.041 1.00 17.31 ? 299 GLU A CB 1 ATOM 2407 C CG . GLU A 1 291 ? 165.368 41.731 -65.365 1.00 18.49 ? 299 GLU A CG 1 ATOM 2408 C CD . GLU A 1 291 ? 163.889 41.437 -65.201 1.00 21.15 ? 299 GLU A CD 1 ATOM 2409 O OE1 . GLU A 1 291 ? 163.191 42.198 -64.497 1.00 23.26 ? 299 GLU A OE1 1 ATOM 2410 O OE2 . GLU A 1 291 ? 163.418 40.439 -65.785 1.00 21.79 ? 299 GLU A OE2 1 ATOM 2411 N N . GLY A 1 292 ? 168.501 42.547 -62.005 1.00 16.68 ? 300 GLY A N 1 ATOM 2412 C CA . GLY A 1 292 ? 168.992 43.454 -60.987 1.00 16.68 ? 300 GLY A CA 1 ATOM 2413 C C . GLY A 1 292 ? 170.453 43.835 -61.116 1.00 17.35 ? 300 GLY A C 1 ATOM 2414 O O . GLY A 1 292 ? 170.992 44.544 -60.265 1.00 16.36 ? 300 GLY A O 1 ATOM 2415 N N . GLU A 1 293 ? 171.109 43.380 -62.175 1.00 18.54 ? 301 GLU A N 1 ATOM 2416 C CA . GLU A 1 293 ? 172.515 43.704 -62.345 1.00 18.82 ? 301 GLU A CA 1 ATOM 2417 C C . GLU A 1 293 ? 172.763 45.207 -62.441 1.00 19.28 ? 301 GLU A C 1 ATOM 2418 O O . GLU A 1 293 ? 173.687 45.726 -61.816 1.00 21.22 ? 301 GLU A O 1 ATOM 2419 C CB . GLU A 1 293 ? 173.066 42.966 -63.559 1.00 18.07 ? 301 GLU A CB 1 ATOM 2420 C CG . GLU A 1 293 ? 173.204 41.481 -63.280 1.00 19.76 ? 301 GLU A CG 1 ATOM 2421 C CD . GLU A 1 293 ? 174.241 41.198 -62.206 1.00 19.42 ? 301 GLU A CD 1 ATOM 2422 O OE1 . GLU A 1 293 ? 175.449 41.332 -62.497 1.00 20.47 ? 301 GLU A OE1 1 ATOM 2423 O OE2 . GLU A 1 293 ? 173.854 40.852 -61.071 1.00 19.65 ? 301 GLU A OE2 1 ATOM 2424 N N . ALA A 1 294 ? 171.926 45.915 -63.192 1.00 19.97 ? 302 ALA A N 1 ATOM 2425 C CA . ALA A 1 294 ? 172.089 47.359 -63.340 1.00 19.56 ? 302 ALA A CA 1 ATOM 2426 C C . ALA A 1 294 ? 172.153 48.074 -61.988 1.00 19.54 ? 302 ALA A C 1 ATOM 2427 O O . ALA A 1 294 ? 173.121 48.770 -61.694 1.00 20.81 ? 302 ALA A O 1 ATOM 2428 C CB . ALA A 1 294 ? 170.952 47.939 -64.186 1.00 18.56 ? 302 ALA A CB 1 ATOM 2429 N N . MET A 1 295 ? 171.140 47.905 -61.151 1.00 19.11 ? 303 MET A N 1 ATOM 2430 C CA . MET A 1 295 ? 171.166 48.581 -59.865 1.00 19.80 ? 303 MET A CA 1 ATOM 2431 C C . MET A 1 295 ? 172.259 48.026 -58.960 1.00 20.49 ? 303 MET A C 1 ATOM 2432 O O . MET A 1 295 ? 172.861 48.761 -58.181 1.00 19.93 ? 303 MET A O 1 ATOM 2433 C CB . MET A 1 295 ? 169.816 48.465 -59.166 1.00 21.34 ? 303 MET A CB 1 ATOM 2434 C CG . MET A 1 295 ? 169.538 49.628 -58.227 1.00 22.96 ? 303 MET A CG 1 ATOM 2435 S SD . MET A 1 295 ? 167.985 49.518 -57.329 1.00 20.92 ? 303 MET A SD 1 ATOM 2436 C CE . MET A 1 295 ? 168.554 48.601 -55.973 1.00 20.33 ? 303 MET A CE 1 ATOM 2437 N N . ARG A 1 296 ? 172.513 46.725 -59.055 1.00 20.98 ? 304 ARG A N 1 ATOM 2438 C CA . ARG A 1 296 ? 173.551 46.103 -58.247 1.00 20.63 ? 304 ARG A CA 1 ATOM 2439 C C . ARG A 1 296 ? 174.912 46.791 -58.434 1.00 21.46 ? 304 ARG A C 1 ATOM 2440 O O . ARG A 1 296 ? 175.564 47.160 -57.455 1.00 21.34 ? 304 ARG A O 1 ATOM 2441 C CB . ARG A 1 296 ? 173.669 44.623 -58.600 1.00 21.15 ? 304 ARG A CB 1 ATOM 2442 C CG . ARG A 1 296 ? 174.727 43.892 -57.799 1.00 21.45 ? 304 ARG A CG 1 ATOM 2443 C CD . ARG A 1 296 ? 174.789 42.425 -58.181 1.00 22.09 ? 304 ARG A CD 1 ATOM 2444 N NE . ARG A 1 296 ? 176.175 42.005 -58.328 1.00 25.55 ? 304 ARG A NE 1 ATOM 2445 C CZ . ARG A 1 296 ? 176.913 42.228 -59.407 1.00 25.47 ? 304 ARG A CZ 1 ATOM 2446 N NH1 . ARG A 1 296 ? 176.393 42.853 -60.440 1.00 27.39 ? 304 ARG A NH1 1 ATOM 2447 N NH2 . ARG A 1 296 ? 178.178 41.851 -59.438 1.00 29.12 ? 304 ARG A NH2 1 ATOM 2448 N N . THR A 1 297 ? 175.333 46.976 -59.687 1.00 21.28 ? 305 THR A N 1 ATOM 2449 C CA . THR A 1 297 ? 176.623 47.608 -59.979 1.00 20.10 ? 305 THR A CA 1 ATOM 2450 C C . THR A 1 297 ? 176.664 49.026 -59.445 1.00 20.23 ? 305 THR A C 1 ATOM 2451 O O . THR A 1 297 ? 177.725 49.615 -59.314 1.00 21.35 ? 305 THR A O 1 ATOM 2452 C CB . THR A 1 297 ? 176.911 47.691 -61.493 1.00 20.63 ? 305 THR A CB 1 ATOM 2453 O OG1 . THR A 1 297 ? 175.981 48.592 -62.107 1.00 19.69 ? 305 THR A OG1 1 ATOM 2454 C CG2 . THR A 1 297 ? 176.788 46.322 -62.142 1.00 17.50 ? 305 THR A CG2 1 ATOM 2455 N N . LYS A 1 298 ? 175.501 49.575 -59.138 1.00 19.95 ? 306 LYS A N 1 ATOM 2456 C CA . LYS A 1 298 ? 175.418 50.934 -58.625 1.00 18.41 ? 306 LYS A CA 1 ATOM 2457 C C . LYS A 1 298 ? 175.476 51.031 -57.094 1.00 18.17 ? 306 LYS A C 1 ATOM 2458 O O . LYS A 1 298 ? 176.265 51.804 -56.535 1.00 16.89 ? 306 LYS A O 1 ATOM 2459 C CB . LYS A 1 298 ? 174.117 51.575 -59.109 1.00 18.71 ? 306 LYS A CB 1 ATOM 2460 C CG . LYS A 1 298 ? 174.274 52.942 -59.718 1.00 20.35 ? 306 LYS A CG 1 ATOM 2461 C CD . LYS A 1 298 ? 175.092 52.881 -60.991 1.00 20.06 ? 306 LYS A CD 1 ATOM 2462 C CE . LYS A 1 298 ? 175.277 54.255 -61.596 1.00 18.76 ? 306 LYS A CE 1 ATOM 2463 N NZ . LYS A 1 298 ? 176.156 54.205 -62.798 1.00 19.62 ? 306 LYS A NZ 1 ATOM 2464 N N . PHE A 1 299 ? 174.656 50.233 -56.414 1.00 16.63 ? 307 PHE A N 1 ATOM 2465 C CA . PHE A 1 299 ? 174.585 50.320 -54.960 1.00 16.24 ? 307 PHE A CA 1 ATOM 2466 C C . PHE A 1 299 ? 175.163 49.211 -54.076 1.00 16.40 ? 307 PHE A C 1 ATOM 2467 O O . PHE A 1 299 ? 175.299 49.399 -52.861 1.00 13.44 ? 307 PHE A O 1 ATOM 2468 C CB . PHE A 1 299 ? 173.129 50.537 -54.547 1.00 17.51 ? 307 PHE A CB 1 ATOM 2469 C CG . PHE A 1 299 ? 172.470 51.702 -55.226 1.00 17.21 ? 307 PHE A CG 1 ATOM 2470 C CD1 . PHE A 1 299 ? 173.175 52.880 -55.472 1.00 16.52 ? 307 PHE A CD1 1 ATOM 2471 C CD2 . PHE A 1 299 ? 171.127 51.637 -55.580 1.00 14.93 ? 307 PHE A CD2 1 ATOM 2472 C CE1 . PHE A 1 299 ? 172.542 53.979 -56.061 1.00 17.15 ? 307 PHE A CE1 1 ATOM 2473 C CE2 . PHE A 1 299 ? 170.495 52.726 -56.163 1.00 15.93 ? 307 PHE A CE2 1 ATOM 2474 C CZ . PHE A 1 299 ? 171.204 53.897 -56.402 1.00 15.54 ? 307 PHE A CZ 1 ATOM 2475 N N . GLU A 1 300 ? 175.500 48.061 -54.648 1.00 16.55 ? 308 GLU A N 1 ATOM 2476 C CA . GLU A 1 300 ? 176.018 46.989 -53.812 1.00 16.88 ? 308 GLU A CA 1 ATOM 2477 C C . GLU A 1 300 ? 177.145 47.430 -52.873 1.00 17.67 ? 308 GLU A C 1 ATOM 2478 O O . GLU A 1 300 ? 177.107 47.144 -51.672 1.00 17.38 ? 308 GLU A O 1 ATOM 2479 C CB . GLU A 1 300 ? 176.489 45.822 -54.666 1.00 16.26 ? 308 GLU A CB 1 ATOM 2480 C CG . GLU A 1 300 ? 177.010 44.681 -53.826 1.00 18.77 ? 308 GLU A CG 1 ATOM 2481 C CD . GLU A 1 300 ? 177.326 43.464 -54.646 1.00 20.07 ? 308 GLU A CD 1 ATOM 2482 O OE1 . GLU A 1 300 ? 177.536 43.626 -55.867 1.00 22.33 ? 308 GLU A OE1 1 ATOM 2483 O OE2 . GLU A 1 300 ? 177.371 42.356 -54.070 1.00 18.86 ? 308 GLU A OE2 1 ATOM 2484 N N . ALA A 1 301 ? 178.140 48.130 -53.413 1.00 19.30 ? 309 ALA A N 1 ATOM 2485 C CA . ALA A 1 301 ? 179.272 48.589 -52.612 1.00 19.18 ? 309 ALA A CA 1 ATOM 2486 C C . ALA A 1 301 ? 178.823 49.415 -51.423 1.00 19.61 ? 309 ALA A C 1 ATOM 2487 O O . ALA A 1 301 ? 179.398 49.301 -50.345 1.00 22.31 ? 309 ALA A O 1 ATOM 2488 C CB . ALA A 1 301 ? 180.231 49.394 -53.465 1.00 18.54 ? 309 ALA A CB 1 ATOM 2489 N N . TRP A 1 302 ? 177.804 50.249 -51.610 1.00 18.65 ? 310 TRP A N 1 ATOM 2490 C CA . TRP A 1 302 ? 177.310 51.066 -50.513 1.00 18.65 ? 310 TRP A CA 1 ATOM 2491 C C . TRP A 1 302 ? 176.675 50.193 -49.437 1.00 18.82 ? 310 TRP A C 1 ATOM 2492 O O . TRP A 1 302 ? 176.910 50.406 -48.252 1.00 19.54 ? 310 TRP A O 1 ATOM 2493 C CB . TRP A 1 302 ? 176.285 52.099 -51.007 1.00 20.22 ? 310 TRP A CB 1 ATOM 2494 C CG . TRP A 1 302 ? 176.838 53.104 -51.979 1.00 21.21 ? 310 TRP A CG 1 ATOM 2495 C CD1 . TRP A 1 302 ? 178.110 53.159 -52.466 1.00 21.73 ? 310 TRP A CD1 1 ATOM 2496 C CD2 . TRP A 1 302 ? 176.118 54.158 -52.628 1.00 21.69 ? 310 TRP A CD2 1 ATOM 2497 N NE1 . TRP A 1 302 ? 178.228 54.173 -53.383 1.00 22.40 ? 310 TRP A NE1 1 ATOM 2498 C CE2 . TRP A 1 302 ? 177.019 54.803 -53.503 1.00 22.06 ? 310 TRP A CE2 1 ATOM 2499 C CE3 . TRP A 1 302 ? 174.798 54.615 -52.558 1.00 21.38 ? 310 TRP A CE3 1 ATOM 2500 C CZ2 . TRP A 1 302 ? 176.645 55.882 -54.303 1.00 22.77 ? 310 TRP A CZ2 1 ATOM 2501 C CZ3 . TRP A 1 302 ? 174.422 55.692 -53.356 1.00 22.64 ? 310 TRP A CZ3 1 ATOM 2502 C CH2 . TRP A 1 302 ? 175.344 56.311 -54.219 1.00 23.34 ? 310 TRP A CH2 1 ATOM 2503 N N . PHE A 1 303 ? 175.874 49.211 -49.839 1.00 18.55 ? 311 PHE A N 1 ATOM 2504 C CA . PHE A 1 303 ? 175.224 48.347 -48.861 1.00 19.99 ? 311 PHE A CA 1 ATOM 2505 C C . PHE A 1 303 ? 176.240 47.637 -47.980 1.00 21.93 ? 311 PHE A C 1 ATOM 2506 O O . PHE A 1 303 ? 175.973 47.372 -46.802 1.00 23.38 ? 311 PHE A O 1 ATOM 2507 C CB . PHE A 1 303 ? 174.352 47.291 -49.540 1.00 19.17 ? 311 PHE A CB 1 ATOM 2508 C CG . PHE A 1 303 ? 173.203 47.851 -50.314 1.00 18.31 ? 311 PHE A CG 1 ATOM 2509 C CD1 . PHE A 1 303 ? 172.825 49.180 -50.171 1.00 18.61 ? 311 PHE A CD1 1 ATOM 2510 C CD2 . PHE A 1 303 ? 172.479 47.035 -51.175 1.00 17.86 ? 311 PHE A CD2 1 ATOM 2511 C CE1 . PHE A 1 303 ? 171.743 49.695 -50.884 1.00 19.05 ? 311 PHE A CE1 1 ATOM 2512 C CE2 . PHE A 1 303 ? 171.401 47.535 -51.888 1.00 18.06 ? 311 PHE A CE2 1 ATOM 2513 C CZ . PHE A 1 303 ? 171.028 48.869 -51.740 1.00 19.18 ? 311 PHE A CZ 1 ATOM 2514 N N . VAL A 1 304 ? 177.394 47.310 -48.552 1.00 22.18 ? 312 VAL A N 1 ATOM 2515 C CA . VAL A 1 304 ? 178.437 46.630 -47.798 1.00 21.97 ? 312 VAL A CA 1 ATOM 2516 C C . VAL A 1 304 ? 179.174 47.653 -46.943 1.00 23.26 ? 312 VAL A C 1 ATOM 2517 O O . VAL A 1 304 ? 179.387 47.443 -45.746 1.00 24.00 ? 312 VAL A O 1 ATOM 2518 C CB . VAL A 1 304 ? 179.426 45.929 -48.742 1.00 20.14 ? 312 VAL A CB 1 ATOM 2519 C CG1 . VAL A 1 304 ? 180.563 45.305 -47.956 1.00 16.90 ? 312 VAL A CG1 1 ATOM 2520 C CG2 . VAL A 1 304 ? 178.691 44.874 -49.547 1.00 19.53 ? 312 VAL A CG2 1 ATOM 2521 N N . LYS A 1 305 ? 179.547 48.765 -47.562 1.00 23.83 ? 313 LYS A N 1 ATOM 2522 C CA . LYS A 1 305 ? 180.249 49.820 -46.855 1.00 25.06 ? 313 LYS A CA 1 ATOM 2523 C C . LYS A 1 305 ? 179.509 50.161 -45.568 1.00 25.51 ? 313 LYS A C 1 ATOM 2524 O O . LYS A 1 305 ? 180.126 50.314 -44.513 1.00 27.20 ? 313 LYS A O 1 ATOM 2525 C CB . LYS A 1 305 ? 180.353 51.063 -47.729 1.00 26.37 ? 313 LYS A CB 1 ATOM 2526 C CG . LYS A 1 305 ? 181.034 52.223 -47.045 1.00 30.32 ? 313 LYS A CG 1 ATOM 2527 C CD . LYS A 1 305 ? 181.106 53.415 -47.974 1.00 35.91 ? 313 LYS A CD 1 ATOM 2528 C CE . LYS A 1 305 ? 181.712 54.624 -47.284 1.00 37.98 ? 313 LYS A CE 1 ATOM 2529 N NZ . LYS A 1 305 ? 181.684 55.813 -48.186 1.00 41.75 ? 313 LYS A NZ 1 ATOM 2530 N N . TYR A 1 306 ? 178.187 50.261 -45.647 1.00 23.35 ? 314 TYR A N 1 ATOM 2531 C CA . TYR A 1 306 ? 177.396 50.599 -44.474 1.00 23.36 ? 314 TYR A CA 1 ATOM 2532 C C . TYR A 1 306 ? 176.815 49.398 -43.749 1.00 24.23 ? 314 TYR A C 1 ATOM 2533 O O . TYR A 1 306 ? 176.013 49.543 -42.819 1.00 24.03 ? 314 TYR A O 1 ATOM 2534 C CB . TYR A 1 306 ? 176.285 51.563 -44.864 1.00 22.96 ? 314 TYR A CB 1 ATOM 2535 C CG . TYR A 1 306 ? 176.814 52.928 -45.223 1.00 23.65 ? 314 TYR A CG 1 ATOM 2536 C CD1 . TYR A 1 306 ? 177.126 53.859 -44.232 1.00 22.67 ? 314 TYR A CD1 1 ATOM 2537 C CD2 . TYR A 1 306 ? 177.042 53.277 -46.552 1.00 24.28 ? 314 TYR A CD2 1 ATOM 2538 C CE1 . TYR A 1 306 ? 177.651 55.106 -44.559 1.00 22.97 ? 314 TYR A CE1 1 ATOM 2539 C CE2 . TYR A 1 306 ? 177.567 54.514 -46.888 1.00 24.37 ? 314 TYR A CE2 1 ATOM 2540 C CZ . TYR A 1 306 ? 177.868 55.427 -45.889 1.00 24.03 ? 314 TYR A CZ 1 ATOM 2541 O OH . TYR A 1 306 ? 178.364 56.666 -46.223 1.00 24.88 ? 314 TYR A OH 1 ATOM 2542 N N . LYS A 1 307 ? 177.222 48.211 -44.178 1.00 24.71 ? 315 LYS A N 1 ATOM 2543 C CA . LYS A 1 307 ? 176.763 46.978 -43.548 1.00 25.60 ? 315 LYS A CA 1 ATOM 2544 C C . LYS A 1 307 ? 175.245 46.900 -43.341 1.00 24.11 ? 315 LYS A C 1 ATOM 2545 O O . LYS A 1 307 ? 174.790 46.774 -42.212 1.00 22.14 ? 315 LYS A O 1 ATOM 2546 C CB . LYS A 1 307 ? 177.474 46.799 -42.190 1.00 26.31 ? 315 LYS A CB 1 ATOM 2547 C CG . LYS A 1 307 ? 178.994 46.938 -42.283 1.00 30.43 ? 315 LYS A CG 1 ATOM 2548 C CD . LYS A 1 307 ? 179.721 46.529 -40.998 1.00 33.87 ? 315 LYS A CD 1 ATOM 2549 C CE . LYS A 1 307 ? 181.242 46.555 -41.217 1.00 36.00 ? 315 LYS A CE 1 ATOM 2550 N NZ . LYS A 1 307 ? 182.013 45.773 -40.199 1.00 38.69 ? 315 LYS A NZ 1 ATOM 2551 N N . VAL A 1 308 ? 174.452 46.974 -44.408 1.00 23.00 ? 316 VAL A N 1 ATOM 2552 C CA . VAL A 1 308 ? 173.008 46.865 -44.209 1.00 22.46 ? 316 VAL A CA 1 ATOM 2553 C C . VAL A 1 308 ? 172.755 45.415 -43.811 1.00 21.69 ? 316 VAL A C 1 ATOM 2554 O O . VAL A 1 308 ? 173.448 44.503 -44.271 1.00 20.34 ? 316 VAL A O 1 ATOM 2555 C CB . VAL A 1 308 ? 172.184 47.222 -45.480 1.00 20.81 ? 316 VAL A CB 1 ATOM 2556 C CG1 . VAL A 1 308 ? 172.531 48.618 -45.942 1.00 19.30 ? 316 VAL A CG1 1 ATOM 2557 C CG2 . VAL A 1 308 ? 172.442 46.230 -46.571 1.00 24.54 ? 316 VAL A CG2 1 ATOM 2558 N N . ASP A 1 309 ? 171.772 45.203 -42.947 1.00 20.87 ? 317 ASP A N 1 ATOM 2559 C CA . ASP A 1 309 ? 171.474 43.862 -42.464 1.00 21.32 ? 317 ASP A CA 1 ATOM 2560 C C . ASP A 1 309 ? 170.767 42.957 -43.460 1.00 21.47 ? 317 ASP A C 1 ATOM 2561 O O . ASP A 1 309 ? 171.269 41.888 -43.804 1.00 21.71 ? 317 ASP A O 1 ATOM 2562 C CB . ASP A 1 309 ? 170.654 43.955 -41.177 1.00 21.47 ? 317 ASP A CB 1 ATOM 2563 C CG . ASP A 1 309 ? 171.465 44.496 -40.014 1.00 22.37 ? 317 ASP A CG 1 ATOM 2564 O OD1 . ASP A 1 309 ? 172.342 43.750 -39.531 1.00 24.54 ? 317 ASP A OD1 1 ATOM 2565 O OD2 . ASP A 1 309 ? 171.245 45.658 -39.592 1.00 21.88 ? 317 ASP A OD2 1 ATOM 2566 N N . VAL A 1 310 ? 169.602 43.390 -43.924 1.00 21.19 ? 318 VAL A N 1 ATOM 2567 C CA . VAL A 1 310 ? 168.815 42.599 -44.859 1.00 20.59 ? 318 VAL A CA 1 ATOM 2568 C C . VAL A 1 310 ? 168.280 43.452 -45.997 1.00 19.31 ? 318 VAL A C 1 ATOM 2569 O O . VAL A 1 310 ? 167.931 44.618 -45.800 1.00 18.36 ? 318 VAL A O 1 ATOM 2570 C CB . VAL A 1 310 ? 167.580 41.994 -44.169 1.00 20.46 ? 318 VAL A CB 1 ATOM 2571 C CG1 . VAL A 1 310 ? 167.224 40.666 -44.803 1.00 22.24 ? 318 VAL A CG1 1 ATOM 2572 C CG2 . VAL A 1 310 ? 167.821 41.860 -42.695 1.00 24.82 ? 318 VAL A CG2 1 ATOM 2573 N N . VAL A 1 311 ? 168.221 42.864 -47.186 1.00 17.86 ? 319 VAL A N 1 ATOM 2574 C CA . VAL A 1 311 ? 167.661 43.546 -48.338 1.00 17.81 ? 319 VAL A CA 1 ATOM 2575 C C . VAL A 1 311 ? 166.481 42.658 -48.754 1.00 18.43 ? 319 VAL A C 1 ATOM 2576 O O . VAL A 1 311 ? 166.648 41.451 -48.943 1.00 19.12 ? 319 VAL A O 1 ATOM 2577 C CB . VAL A 1 311 ? 168.671 43.651 -49.516 1.00 17.03 ? 319 VAL A CB 1 ATOM 2578 C CG1 . VAL A 1 311 ? 168.020 44.368 -50.690 1.00 14.02 ? 319 VAL A CG1 1 ATOM 2579 C CG2 . VAL A 1 311 ? 169.920 44.406 -49.080 1.00 15.99 ? 319 VAL A CG2 1 ATOM 2580 N N . PHE A 1 312 ? 165.290 43.242 -48.861 1.00 18.31 ? 320 PHE A N 1 ATOM 2581 C CA . PHE A 1 312 ? 164.099 42.496 -49.264 1.00 17.60 ? 320 PHE A CA 1 ATOM 2582 C C . PHE A 1 312 ? 163.663 42.926 -50.664 1.00 17.55 ? 320 PHE A C 1 ATOM 2583 O O . PHE A 1 312 ? 163.634 44.118 -50.970 1.00 18.73 ? 320 PHE A O 1 ATOM 2584 C CB . PHE A 1 312 ? 162.949 42.755 -48.288 1.00 17.24 ? 320 PHE A CB 1 ATOM 2585 C CG . PHE A 1 312 ? 163.147 42.149 -46.925 1.00 17.70 ? 320 PHE A CG 1 ATOM 2586 C CD1 . PHE A 1 312 ? 163.174 40.771 -46.758 1.00 18.09 ? 320 PHE A CD1 1 ATOM 2587 C CD2 . PHE A 1 312 ? 163.303 42.960 -45.807 1.00 17.92 ? 320 PHE A CD2 1 ATOM 2588 C CE1 . PHE A 1 312 ? 163.353 40.208 -45.497 1.00 17.54 ? 320 PHE A CE1 1 ATOM 2589 C CE2 . PHE A 1 312 ? 163.483 42.409 -44.542 1.00 17.72 ? 320 PHE A CE2 1 ATOM 2590 C CZ . PHE A 1 312 ? 163.508 41.031 -44.384 1.00 17.70 ? 320 PHE A CZ 1 ATOM 2591 N N . ALA A 1 313 ? 163.326 41.957 -51.509 1.00 15.71 ? 321 ALA A N 1 ATOM 2592 C CA . ALA A 1 313 ? 162.870 42.244 -52.863 1.00 14.45 ? 321 ALA A CA 1 ATOM 2593 C C . ALA A 1 313 ? 161.766 41.263 -53.233 1.00 14.36 ? 321 ALA A C 1 ATOM 2594 O O . ALA A 1 313 ? 161.576 40.250 -52.559 1.00 16.25 ? 321 ALA A O 1 ATOM 2595 C CB . ALA A 1 313 ? 164.020 42.124 -53.851 1.00 12.76 ? 321 ALA A CB 1 ATOM 2596 N N . GLY A 1 314 ? 161.032 41.571 -54.295 1.00 12.88 ? 322 GLY A N 1 ATOM 2597 C CA . GLY A 1 314 ? 159.977 40.679 -54.736 1.00 13.44 ? 322 GLY A CA 1 ATOM 2598 C C . GLY A 1 314 ? 160.249 40.331 -56.187 1.00 14.67 ? 322 GLY A C 1 ATOM 2599 O O . GLY A 1 314 ? 161.278 39.710 -56.497 1.00 12.56 ? 322 GLY A O 1 ATOM 2600 N N . HIS A 1 315 ? 159.322 40.719 -57.066 1.00 14.25 ? 323 HIS A N 1 ATOM 2601 C CA . HIS A 1 315 ? 159.453 40.525 -58.507 1.00 15.73 ? 323 HIS A CA 1 ATOM 2602 C C . HIS A 1 315 ? 159.474 39.082 -58.998 1.00 17.33 ? 323 HIS A C 1 ATOM 2603 O O . HIS A 1 315 ? 158.740 38.746 -59.930 1.00 19.52 ? 323 HIS A O 1 ATOM 2604 C CB . HIS A 1 315 ? 160.690 41.276 -59.008 1.00 16.64 ? 323 HIS A CB 1 ATOM 2605 C CG . HIS A 1 315 ? 160.667 41.576 -60.475 1.00 18.53 ? 323 HIS A CG 1 ATOM 2606 N ND1 . HIS A 1 315 ? 159.579 42.154 -61.102 1.00 18.70 ? 323 HIS A ND1 1 ATOM 2607 C CD2 . HIS A 1 315 ? 161.608 41.416 -61.434 1.00 17.40 ? 323 HIS A CD2 1 ATOM 2608 C CE1 . HIS A 1 315 ? 159.855 42.337 -62.378 1.00 18.70 ? 323 HIS A CE1 1 ATOM 2609 N NE2 . HIS A 1 315 ? 161.083 41.897 -62.607 1.00 19.27 ? 323 HIS A NE2 1 ATOM 2610 N N . VAL A 1 316 ? 160.328 38.239 -58.423 1.00 17.17 ? 324 VAL A N 1 ATOM 2611 C CA . VAL A 1 316 ? 160.357 36.833 -58.808 1.00 17.57 ? 324 VAL A CA 1 ATOM 2612 C C . VAL A 1 316 ? 159.276 36.204 -57.940 1.00 19.26 ? 324 VAL A C 1 ATOM 2613 O O . VAL A 1 316 ? 159.253 36.405 -56.722 1.00 19.23 ? 324 VAL A O 1 ATOM 2614 C CB . VAL A 1 316 ? 161.713 36.173 -58.491 1.00 18.56 ? 324 VAL A CB 1 ATOM 2615 C CG1 . VAL A 1 316 ? 161.587 34.652 -58.563 1.00 17.11 ? 324 VAL A CG1 1 ATOM 2616 C CG2 . VAL A 1 316 ? 162.765 36.657 -59.481 1.00 17.80 ? 324 VAL A CG2 1 ATOM 2617 N N . HIS A 1 317 ? 158.372 35.451 -58.553 1.00 19.96 ? 325 HIS A N 1 ATOM 2618 C CA . HIS A 1 317 ? 157.283 34.856 -57.796 1.00 21.07 ? 325 HIS A CA 1 ATOM 2619 C C . HIS A 1 317 ? 157.680 33.536 -57.185 1.00 21.56 ? 325 HIS A C 1 ATOM 2620 O O . HIS A 1 317 ? 157.269 32.465 -57.630 1.00 21.48 ? 325 HIS A O 1 ATOM 2621 C CB . HIS A 1 317 ? 156.062 34.728 -58.697 1.00 21.79 ? 325 HIS A CB 1 ATOM 2622 C CG . HIS A 1 317 ? 155.620 36.042 -59.262 1.00 24.60 ? 325 HIS A CG 1 ATOM 2623 N ND1 . HIS A 1 317 ? 154.644 36.157 -60.229 1.00 26.75 ? 325 HIS A ND1 1 ATOM 2624 C CD2 . HIS A 1 317 ? 156.034 37.303 -58.995 1.00 23.68 ? 325 HIS A CD2 1 ATOM 2625 C CE1 . HIS A 1 317 ? 154.478 37.432 -60.534 1.00 26.20 ? 325 HIS A CE1 1 ATOM 2626 N NE2 . HIS A 1 317 ? 155.310 38.148 -59.799 1.00 26.00 ? 325 HIS A NE2 1 ATOM 2627 N N . ALA A 1 318 ? 158.500 33.642 -56.147 1.00 21.54 ? 326 ALA A N 1 ATOM 2628 C CA . ALA A 1 318 ? 159.009 32.489 -55.429 1.00 21.82 ? 326 ALA A CA 1 ATOM 2629 C C . ALA A 1 318 ? 159.739 32.991 -54.195 1.00 22.75 ? 326 ALA A C 1 ATOM 2630 O O . ALA A 1 318 ? 159.658 34.180 -53.857 1.00 21.75 ? 326 ALA A O 1 ATOM 2631 C CB . ALA A 1 318 ? 159.966 31.706 -56.316 1.00 20.97 ? 326 ALA A CB 1 ATOM 2632 N N . TYR A 1 319 ? 160.454 32.085 -53.530 1.00 22.37 ? 327 TYR A N 1 ATOM 2633 C CA . TYR A 1 319 ? 161.195 32.435 -52.327 1.00 21.84 ? 327 TYR A CA 1 ATOM 2634 C C . TYR A 1 319 ? 162.661 32.050 -52.441 1.00 21.51 ? 327 TYR A C 1 ATOM 2635 O O . TYR A 1 319 ? 162.994 30.960 -52.907 1.00 22.11 ? 327 TYR A O 1 ATOM 2636 C CB . TYR A 1 319 ? 160.591 31.739 -51.106 1.00 23.02 ? 327 TYR A CB 1 ATOM 2637 C CG . TYR A 1 319 ? 161.376 31.959 -49.829 1.00 23.38 ? 327 TYR A CG 1 ATOM 2638 C CD1 . TYR A 1 319 ? 161.442 33.219 -49.235 1.00 22.76 ? 327 TYR A CD1 1 ATOM 2639 C CD2 . TYR A 1 319 ? 162.079 30.911 -49.231 1.00 23.52 ? 327 TYR A CD2 1 ATOM 2640 C CE1 . TYR A 1 319 ? 162.188 33.433 -48.079 1.00 23.49 ? 327 TYR A CE1 1 ATOM 2641 C CE2 . TYR A 1 319 ? 162.834 31.113 -48.068 1.00 22.66 ? 327 TYR A CE2 1 ATOM 2642 C CZ . TYR A 1 319 ? 162.883 32.377 -47.500 1.00 23.73 ? 327 TYR A CZ 1 ATOM 2643 O OH . TYR A 1 319 ? 163.630 32.587 -46.357 1.00 24.95 ? 327 TYR A OH 1 ATOM 2644 N N . GLU A 1 320 ? 163.534 32.964 -52.029 1.00 20.92 ? 328 GLU A N 1 ATOM 2645 C CA . GLU A 1 320 ? 164.966 32.709 -52.044 1.00 20.38 ? 328 GLU A CA 1 ATOM 2646 C C . GLU A 1 320 ? 165.667 33.479 -50.933 1.00 21.21 ? 328 GLU A C 1 ATOM 2647 O O . GLU A 1 320 ? 165.277 34.601 -50.592 1.00 21.23 ? 328 GLU A O 1 ATOM 2648 C CB . GLU A 1 320 ? 165.581 33.071 -53.392 1.00 17.74 ? 328 GLU A CB 1 ATOM 2649 C CG . GLU A 1 320 ? 167.097 32.915 -53.412 1.00 16.85 ? 328 GLU A CG 1 ATOM 2650 C CD . GLU A 1 320 ? 167.668 32.729 -54.805 1.00 15.87 ? 328 GLU A CD 1 ATOM 2651 O OE1 . GLU A 1 320 ? 167.205 33.397 -55.761 1.00 18.20 ? 328 GLU A OE1 1 ATOM 2652 O OE2 . GLU A 1 320 ? 168.596 31.914 -54.943 1.00 15.52 ? 328 GLU A OE2 1 ATOM 2653 N N . ARG A 1 321 ? 166.698 32.859 -50.370 1.00 21.24 ? 329 ARG A N 1 ATOM 2654 C CA . ARG A 1 321 ? 167.473 33.448 -49.283 1.00 21.71 ? 329 ARG A CA 1 ATOM 2655 C C . ARG A 1 321 ? 168.943 33.231 -49.601 1.00 21.03 ? 329 ARG A C 1 ATOM 2656 O O . ARG A 1 321 ? 169.389 32.094 -49.761 1.00 21.09 ? 329 ARG A O 1 ATOM 2657 C CB . ARG A 1 321 ? 167.135 32.760 -47.953 1.00 22.80 ? 329 ARG A CB 1 ATOM 2658 C CG . ARG A 1 321 ? 167.679 33.465 -46.731 1.00 23.88 ? 329 ARG A CG 1 ATOM 2659 C CD . ARG A 1 321 ? 167.394 32.671 -45.469 1.00 24.18 ? 329 ARG A CD 1 ATOM 2660 N NE . ARG A 1 321 ? 168.474 31.737 -45.177 1.00 25.54 ? 329 ARG A NE 1 ATOM 2661 C CZ . ARG A 1 321 ? 168.287 30.469 -44.840 1.00 25.59 ? 329 ARG A CZ 1 ATOM 2662 N NH1 . ARG A 1 321 ? 167.061 29.975 -44.755 1.00 25.61 ? 329 ARG A NH1 1 ATOM 2663 N NH2 . ARG A 1 321 ? 169.327 29.697 -44.583 1.00 27.73 ? 329 ARG A NH2 1 ATOM 2664 N N . SER A 1 322 ? 169.695 34.320 -49.687 1.00 20.25 ? 330 SER A N 1 ATOM 2665 C CA . SER A 1 322 ? 171.108 34.228 -50.007 1.00 20.49 ? 330 SER A CA 1 ATOM 2666 C C . SER A 1 322 ? 171.932 34.140 -48.747 1.00 22.72 ? 330 SER A C 1 ATOM 2667 O O . SER A 1 322 ? 171.419 34.204 -47.631 1.00 23.21 ? 330 SER A O 1 ATOM 2668 C CB . SER A 1 322 ? 171.568 35.465 -50.774 1.00 18.84 ? 330 SER A CB 1 ATOM 2669 O OG . SER A 1 322 ? 171.768 36.565 -49.896 1.00 16.42 ? 330 SER A OG 1 ATOM 2670 N N . GLU A 1 323 ? 173.229 33.994 -48.947 1.00 24.06 ? 331 GLU A N 1 ATOM 2671 C CA . GLU A 1 323 ? 174.164 33.965 -47.852 1.00 25.83 ? 331 GLU A CA 1 ATOM 2672 C C . GLU A 1 323 ? 174.755 35.354 -47.952 1.00 24.32 ? 331 GLU A C 1 ATOM 2673 O O . GLU A 1 323 ? 174.510 36.059 -48.928 1.00 25.44 ? 331 GLU A O 1 ATOM 2674 C CB . GLU A 1 323 ? 175.226 32.905 -48.109 1.00 29.26 ? 331 GLU A CB 1 ATOM 2675 C CG . GLU A 1 323 ? 174.609 31.610 -48.583 1.00 36.86 ? 331 GLU A CG 1 ATOM 2676 C CD . GLU A 1 323 ? 175.284 30.390 -48.009 1.00 40.24 ? 331 GLU A CD 1 ATOM 2677 O OE1 . GLU A 1 323 ? 175.144 30.160 -46.784 1.00 40.19 ? 331 GLU A OE1 1 ATOM 2678 O OE2 . GLU A 1 323 ? 175.949 29.672 -48.794 1.00 43.47 ? 331 GLU A OE2 1 ATOM 2679 N N . ARG A 1 324 ? 175.512 35.770 -46.953 1.00 23.60 ? 332 ARG A N 1 ATOM 2680 C CA . ARG A 1 324 ? 176.109 37.088 -47.014 1.00 22.41 ? 332 ARG A CA 1 ATOM 2681 C C . ARG A 1 324 ? 177.250 37.024 -48.023 1.00 22.16 ? 332 ARG A C 1 ATOM 2682 O O . ARG A 1 324 ? 178.300 36.431 -47.761 1.00 23.35 ? 332 ARG A O 1 ATOM 2683 C CB . ARG A 1 324 ? 176.603 37.504 -45.626 1.00 20.73 ? 332 ARG A CB 1 ATOM 2684 C CG . ARG A 1 324 ? 175.469 37.644 -44.627 1.00 18.95 ? 332 ARG A CG 1 ATOM 2685 C CD . ARG A 1 324 ? 175.970 38.107 -43.271 1.00 21.75 ? 332 ARG A CD 1 ATOM 2686 N NE . ARG A 1 324 ? 174.882 38.272 -42.307 1.00 22.52 ? 332 ARG A NE 1 ATOM 2687 C CZ . ARG A 1 324 ? 173.992 39.260 -42.343 1.00 22.66 ? 332 ARG A CZ 1 ATOM 2688 N NH1 . ARG A 1 324 ? 174.058 40.186 -43.293 1.00 22.07 ? 332 ARG A NH1 1 ATOM 2689 N NH2 . ARG A 1 324 ? 173.023 39.314 -41.439 1.00 22.07 ? 332 ARG A NH2 1 ATOM 2690 N N . VAL A 1 325 ? 177.025 37.604 -49.196 1.00 21.39 ? 333 VAL A N 1 ATOM 2691 C CA . VAL A 1 325 ? 178.042 37.618 -50.242 1.00 22.69 ? 333 VAL A CA 1 ATOM 2692 C C . VAL A 1 325 ? 178.142 38.992 -50.883 1.00 22.65 ? 333 VAL A C 1 ATOM 2693 O O . VAL A 1 325 ? 177.266 39.839 -50.710 1.00 23.86 ? 333 VAL A O 1 ATOM 2694 C CB . VAL A 1 325 ? 177.723 36.613 -51.371 1.00 21.46 ? 333 VAL A CB 1 ATOM 2695 C CG1 . VAL A 1 325 ? 177.691 35.207 -50.825 1.00 23.16 ? 333 VAL A CG1 1 ATOM 2696 C CG2 . VAL A 1 325 ? 176.400 36.971 -52.014 1.00 21.38 ? 333 VAL A CG2 1 ATOM 2697 N N . SER A 1 326 ? 179.219 39.210 -51.623 1.00 22.50 ? 334 SER A N 1 ATOM 2698 C CA . SER A 1 326 ? 179.397 40.470 -52.326 1.00 22.97 ? 334 SER A CA 1 ATOM 2699 C C . SER A 1 326 ? 180.175 40.216 -53.602 1.00 22.46 ? 334 SER A C 1 ATOM 2700 O O . SER A 1 326 ? 180.995 39.296 -53.689 1.00 22.80 ? 334 SER A O 1 ATOM 2701 C CB . SER A 1 326 ? 180.134 41.491 -51.460 1.00 22.84 ? 334 SER A CB 1 ATOM 2702 O OG . SER A 1 326 ? 181.473 41.098 -51.246 1.00 22.12 ? 334 SER A OG 1 ATOM 2703 N N . ASN A 1 327 ? 179.897 41.026 -54.606 1.00 22.18 ? 335 ASN A N 1 ATOM 2704 C CA . ASN A 1 327 ? 180.576 40.889 -55.882 1.00 22.48 ? 335 ASN A CA 1 ATOM 2705 C C . ASN A 1 327 ? 181.049 42.284 -56.233 1.00 21.24 ? 335 ASN A C 1 ATOM 2706 O O . ASN A 1 327 ? 180.633 42.845 -57.241 1.00 23.01 ? 335 ASN A O 1 ATOM 2707 C CB . ASN A 1 327 ? 179.595 40.380 -56.943 1.00 22.37 ? 335 ASN A CB 1 ATOM 2708 C CG . ASN A 1 327 ? 180.298 39.827 -58.156 1.00 23.73 ? 335 ASN A CG 1 ATOM 2709 O OD1 . ASN A 1 327 ? 181.507 40.006 -58.313 1.00 25.39 ? 335 ASN A OD1 1 ATOM 2710 N ND2 . ASN A 1 327 ? 179.551 39.153 -59.026 1.00 22.36 ? 335 ASN A ND2 1 ATOM 2711 N N . ILE A 1 328 ? 181.914 42.851 -55.397 1.00 20.77 ? 336 ILE A N 1 ATOM 2712 C CA . ILE A 1 328 ? 182.378 44.209 -55.634 1.00 19.75 ? 336 ILE A CA 1 ATOM 2713 C C . ILE A 1 328 ? 183.850 44.384 -55.952 1.00 20.90 ? 336 ILE A C 1 ATOM 2714 O O . ILE A 1 328 ? 184.356 45.499 -55.896 1.00 22.53 ? 336 ILE A O 1 ATOM 2715 C CB . ILE A 1 328 ? 182.048 45.127 -54.438 1.00 17.59 ? 336 ILE A CB 1 ATOM 2716 C CG1 . ILE A 1 328 ? 182.794 44.655 -53.190 1.00 17.49 ? 336 ILE A CG1 1 ATOM 2717 C CG2 . ILE A 1 328 ? 180.545 45.132 -54.180 1.00 17.36 ? 336 ILE A CG2 1 ATOM 2718 C CD1 . ILE A 1 328 ? 182.744 45.671 -52.039 1.00 15.63 ? 336 ILE A CD1 1 ATOM 2719 N N . ALA A 1 329 ? 184.540 43.304 -56.292 1.00 20.21 ? 337 ALA A N 1 ATOM 2720 C CA . ALA A 1 329 ? 185.954 43.417 -56.613 1.00 20.71 ? 337 ALA A CA 1 ATOM 2721 C C . ALA A 1 329 ? 186.228 43.503 -58.118 1.00 21.77 ? 337 ALA A C 1 ATOM 2722 O O . ALA A 1 329 ? 187.374 43.669 -58.533 1.00 22.14 ? 337 ALA A O 1 ATOM 2723 C CB . ALA A 1 329 ? 186.709 42.244 -56.017 1.00 21.13 ? 337 ALA A CB 1 ATOM 2724 N N . TYR A 1 330 ? 185.177 43.401 -58.930 1.00 23.07 ? 338 TYR A N 1 ATOM 2725 C CA . TYR A 1 330 ? 185.301 43.438 -60.392 1.00 21.89 ? 338 TYR A CA 1 ATOM 2726 C C . TYR A 1 330 ? 185.820 44.752 -60.959 1.00 22.56 ? 338 TYR A C 1 ATOM 2727 O O . TYR A 1 330 ? 185.378 45.830 -60.566 1.00 21.88 ? 338 TYR A O 1 ATOM 2728 C CB . TYR A 1 330 ? 183.948 43.150 -61.036 1.00 20.80 ? 338 TYR A CB 1 ATOM 2729 C CG . TYR A 1 330 ? 183.963 43.058 -62.550 1.00 20.08 ? 338 TYR A CG 1 ATOM 2730 C CD1 . TYR A 1 330 ? 184.769 42.121 -63.208 1.00 19.78 ? 338 TYR A CD1 1 ATOM 2731 C CD2 . TYR A 1 330 ? 183.104 43.840 -63.323 1.00 19.59 ? 338 TYR A CD2 1 ATOM 2732 C CE1 . TYR A 1 330 ? 184.711 41.954 -64.596 1.00 18.46 ? 338 TYR A CE1 1 ATOM 2733 C CE2 . TYR A 1 330 ? 183.037 43.683 -64.719 1.00 19.79 ? 338 TYR A CE2 1 ATOM 2734 C CZ . TYR A 1 330 ? 183.839 42.732 -65.343 1.00 19.89 ? 338 TYR A CZ 1 ATOM 2735 O OH . TYR A 1 330 ? 183.732 42.524 -66.703 1.00 19.99 ? 338 TYR A OH 1 ATOM 2736 N N . LYS A 1 331 ? 186.747 44.657 -61.904 1.00 22.50 ? 339 LYS A N 1 ATOM 2737 C CA . LYS A 1 331 ? 187.291 45.843 -62.539 1.00 23.43 ? 339 LYS A CA 1 ATOM 2738 C C . LYS A 1 331 ? 187.431 45.662 -64.046 1.00 24.23 ? 339 LYS A C 1 ATOM 2739 O O . LYS A 1 331 ? 188.407 46.108 -64.656 1.00 23.73 ? 339 LYS A O 1 ATOM 2740 C CB . LYS A 1 331 ? 188.632 46.208 -61.919 1.00 25.32 ? 339 LYS A CB 1 ATOM 2741 C CG . LYS A 1 331 ? 188.518 46.761 -60.518 1.00 27.63 ? 339 LYS A CG 1 ATOM 2742 C CD . LYS A 1 331 ? 189.839 47.365 -60.077 1.00 33.58 ? 339 LYS A CD 1 ATOM 2743 C CE . LYS A 1 331 ? 189.808 47.759 -58.603 1.00 36.66 ? 339 LYS A CE 1 ATOM 2744 N NZ . LYS A 1 331 ? 188.591 48.573 -58.286 1.00 38.77 ? 339 LYS A NZ 1 ATOM 2745 N N . ILE A 1 332 ? 186.430 45.009 -64.635 1.00 23.34 ? 340 ILE A N 1 ATOM 2746 C CA . ILE A 1 332 ? 186.376 44.758 -66.070 1.00 22.92 ? 340 ILE A CA 1 ATOM 2747 C C . ILE A 1 332 ? 187.375 43.725 -66.600 1.00 24.03 ? 340 ILE A C 1 ATOM 2748 O O . ILE A 1 332 ? 186.995 42.784 -67.302 1.00 23.25 ? 340 ILE A O 1 ATOM 2749 C CB . ILE A 1 332 ? 186.589 46.059 -66.891 1.00 22.61 ? 340 ILE A CB 1 ATOM 2750 C CG1 . ILE A 1 332 ? 185.654 47.173 -66.402 1.00 21.20 ? 340 ILE A CG1 1 ATOM 2751 C CG2 . ILE A 1 332 ? 186.344 45.768 -68.373 1.00 21.19 ? 340 ILE A CG2 1 ATOM 2752 C CD1 . ILE A 1 332 ? 184.189 46.900 -66.644 1.00 22.92 ? 340 ILE A CD1 1 ATOM 2753 N N . THR A 1 333 ? 188.650 43.884 -66.266 1.00 23.85 ? 341 THR A N 1 ATOM 2754 C CA . THR A 1 333 ? 189.650 42.960 -66.791 1.00 25.07 ? 341 THR A CA 1 ATOM 2755 C C . THR A 1 333 ? 190.488 42.199 -65.768 1.00 25.31 ? 341 THR A C 1 ATOM 2756 O O . THR A 1 333 ? 191.446 41.518 -66.137 1.00 26.13 ? 341 THR A O 1 ATOM 2757 C CB . THR A 1 333 ? 190.589 43.709 -67.754 1.00 25.39 ? 341 THR A CB 1 ATOM 2758 O OG1 . THR A 1 333 ? 191.288 44.737 -67.041 1.00 25.99 ? 341 THR A OG1 1 ATOM 2759 C CG2 . THR A 1 333 ? 189.779 44.357 -68.876 1.00 26.13 ? 341 THR A CG2 1 ATOM 2760 N N . ASN A 1 334 ? 190.111 42.297 -64.495 1.00 24.71 ? 342 ASN A N 1 ATOM 2761 C CA . ASN A 1 334 ? 190.837 41.637 -63.416 1.00 23.61 ? 342 ASN A CA 1 ATOM 2762 C C . ASN A 1 334 ? 190.269 40.252 -63.095 1.00 22.47 ? 342 ASN A C 1 ATOM 2763 O O . ASN A 1 334 ? 190.730 39.585 -62.163 1.00 22.34 ? 342 ASN A O 1 ATOM 2764 C CB . ASN A 1 334 ? 190.807 42.518 -62.164 1.00 24.88 ? 342 ASN A CB 1 ATOM 2765 C CG . ASN A 1 334 ? 189.441 42.552 -61.504 1.00 26.46 ? 342 ASN A CG 1 ATOM 2766 O OD1 . ASN A 1 334 ? 188.420 42.436 -62.217 1.00 26.87 ? 342 ASN A OD1 1 ATOM 2767 N ND2 . ASN A 1 334 ? 189.391 42.704 -60.264 1.00 29.63 ? 342 ASN A ND2 1 ATOM 2768 N N . GLY A 1 335 ? 189.264 39.829 -63.858 1.00 20.28 ? 343 GLY A N 1 ATOM 2769 C CA . GLY A 1 335 ? 188.672 38.520 -63.653 1.00 19.13 ? 343 GLY A CA 1 ATOM 2770 C C . GLY A 1 335 ? 187.962 38.235 -62.339 1.00 20.55 ? 343 GLY A C 1 ATOM 2771 O O . GLY A 1 335 ? 187.373 37.164 -62.193 1.00 22.84 ? 343 GLY A O 1 ATOM 2772 N N . LEU A 1 336 ? 187.998 39.155 -61.381 1.00 19.54 ? 344 LEU A N 1 ATOM 2773 C CA . LEU A 1 336 ? 187.331 38.909 -60.106 1.00 20.04 ? 344 LEU A CA 1 ATOM 2774 C C . LEU A 1 336 ? 185.851 39.215 -60.223 1.00 19.84 ? 344 LEU A C 1 ATOM 2775 O O . LEU A 1 336 ? 185.406 40.288 -59.812 1.00 20.72 ? 344 LEU A O 1 ATOM 2776 C CB . LEU A 1 336 ? 187.941 39.778 -59.005 1.00 19.73 ? 344 LEU A CB 1 ATOM 2777 C CG . LEU A 1 336 ? 189.392 39.452 -58.675 1.00 20.34 ? 344 LEU A CG 1 ATOM 2778 C CD1 . LEU A 1 336 ? 189.848 40.331 -57.534 1.00 22.01 ? 344 LEU A CD1 1 ATOM 2779 C CD2 . LEU A 1 336 ? 189.523 37.980 -58.305 1.00 21.27 ? 344 LEU A CD2 1 ATOM 2780 N N . CYS A 1 337 ? 185.084 38.280 -60.777 1.00 18.89 ? 345 CYS A N 1 ATOM 2781 C CA . CYS A 1 337 ? 183.659 38.516 -60.953 1.00 18.61 ? 345 CYS A CA 1 ATOM 2782 C C . CYS A 1 337 ? 182.773 37.435 -60.375 1.00 18.91 ? 345 CYS A C 1 ATOM 2783 O O . CYS A 1 337 ? 181.657 37.219 -60.848 1.00 18.98 ? 345 CYS A O 1 ATOM 2784 C CB . CYS A 1 337 ? 183.330 38.701 -62.432 1.00 19.30 ? 345 CYS A CB 1 ATOM 2785 S SG . CYS A 1 337 ? 183.870 37.346 -63.522 1.00 22.28 ? 345 CYS A SG 1 ATOM 2786 N N . THR A 1 338 ? 183.272 36.746 -59.357 1.00 18.85 ? 346 THR A N 1 ATOM 2787 C CA . THR A 1 338 ? 182.491 35.712 -58.700 1.00 19.71 ? 346 THR A CA 1 ATOM 2788 C C . THR A 1 338 ? 182.144 36.188 -57.304 1.00 20.10 ? 346 THR A C 1 ATOM 2789 O O . THR A 1 338 ? 182.994 36.732 -56.592 1.00 19.38 ? 346 THR A O 1 ATOM 2790 C CB . THR A 1 338 ? 183.262 34.402 -58.579 1.00 19.38 ? 346 THR A CB 1 ATOM 2791 O OG1 . THR A 1 338 ? 183.664 33.976 -59.887 1.00 21.32 ? 346 THR A OG1 1 ATOM 2792 C CG2 . THR A 1 338 ? 182.378 33.324 -57.947 1.00 18.71 ? 346 THR A CG2 1 ATOM 2793 N N . PRO A 1 339 ? 180.877 36.014 -56.901 1.00 21.36 ? 347 PRO A N 1 ATOM 2794 C CA . PRO A 1 339 ? 180.440 36.437 -55.568 1.00 22.67 ? 347 PRO A CA 1 ATOM 2795 C C . PRO A 1 339 ? 181.205 35.654 -54.508 1.00 24.64 ? 347 PRO A C 1 ATOM 2796 O O . PRO A 1 339 ? 181.359 34.430 -54.608 1.00 25.02 ? 347 PRO A O 1 ATOM 2797 C CB . PRO A 1 339 ? 178.945 36.116 -55.578 1.00 21.46 ? 347 PRO A CB 1 ATOM 2798 C CG . PRO A 1 339 ? 178.575 36.286 -57.011 1.00 20.25 ? 347 PRO A CG 1 ATOM 2799 C CD . PRO A 1 339 ? 179.724 35.591 -57.714 1.00 21.01 ? 347 PRO A CD 1 ATOM 2800 N N . VAL A 1 340 ? 181.691 36.373 -53.504 1.00 25.57 ? 348 VAL A N 1 ATOM 2801 C CA . VAL A 1 340 ? 182.460 35.777 -52.422 1.00 26.17 ? 348 VAL A CA 1 ATOM 2802 C C . VAL A 1 340 ? 181.754 36.020 -51.084 1.00 26.74 ? 348 VAL A C 1 ATOM 2803 O O . VAL A 1 340 ? 181.074 37.031 -50.915 1.00 26.40 ? 348 VAL A O 1 ATOM 2804 C CB . VAL A 1 340 ? 183.867 36.402 -52.394 1.00 25.46 ? 348 VAL A CB 1 ATOM 2805 C CG1 . VAL A 1 340 ? 183.755 37.909 -52.240 1.00 24.80 ? 348 VAL A CG1 1 ATOM 2806 C CG2 . VAL A 1 340 ? 184.678 35.813 -51.271 1.00 29.92 ? 348 VAL A CG2 1 ATOM 2807 N N . LYS A 1 341 ? 181.896 35.097 -50.135 1.00 28.19 ? 349 LYS A N 1 ATOM 2808 C CA . LYS A 1 341 ? 181.259 35.292 -48.833 1.00 29.55 ? 349 LYS A CA 1 ATOM 2809 C C . LYS A 1 341 ? 181.829 36.557 -48.201 1.00 29.06 ? 349 LYS A C 1 ATOM 2810 O O . LYS A 1 341 ? 183.037 36.807 -48.264 1.00 28.46 ? 349 LYS A O 1 ATOM 2811 C CB . LYS A 1 341 ? 181.504 34.101 -47.907 1.00 31.33 ? 349 LYS A CB 1 ATOM 2812 C CG . LYS A 1 341 ? 180.729 32.844 -48.280 1.00 36.53 ? 349 LYS A CG 1 ATOM 2813 C CD . LYS A 1 341 ? 180.554 31.927 -47.070 1.00 40.36 ? 349 LYS A CD 1 ATOM 2814 C CE . LYS A 1 341 ? 179.852 30.617 -47.438 1.00 43.59 ? 349 LYS A CE 1 ATOM 2815 N NZ . LYS A 1 341 ? 180.683 29.740 -48.326 1.00 44.62 ? 349 LYS A NZ 1 ATOM 2816 N N . ASP A 1 342 ? 180.953 37.351 -47.597 1.00 27.96 ? 350 ASP A N 1 ATOM 2817 C CA . ASP A 1 342 ? 181.354 38.611 -46.977 1.00 27.91 ? 350 ASP A CA 1 ATOM 2818 C C . ASP A 1 342 ? 180.507 38.845 -45.724 1.00 27.89 ? 350 ASP A C 1 ATOM 2819 O O . ASP A 1 342 ? 179.294 39.032 -45.813 1.00 26.63 ? 350 ASP A O 1 ATOM 2820 C CB . ASP A 1 342 ? 181.130 39.750 -47.971 1.00 27.39 ? 350 ASP A CB 1 ATOM 2821 C CG . ASP A 1 342 ? 181.910 40.991 -47.629 1.00 27.44 ? 350 ASP A CG 1 ATOM 2822 O OD1 . ASP A 1 342 ? 182.227 41.191 -46.436 1.00 29.29 ? 350 ASP A OD1 1 ATOM 2823 O OD2 . ASP A 1 342 ? 182.191 41.773 -48.562 1.00 26.65 ? 350 ASP A OD2 1 ATOM 2824 N N . GLN A 1 343 ? 181.147 38.831 -44.558 1.00 28.31 ? 351 GLN A N 1 ATOM 2825 C CA . GLN A 1 343 ? 180.439 39.022 -43.296 1.00 28.36 ? 351 GLN A CA 1 ATOM 2826 C C . GLN A 1 343 ? 179.984 40.457 -43.087 1.00 27.52 ? 351 GLN A C 1 ATOM 2827 O O . GLN A 1 343 ? 179.258 40.764 -42.135 1.00 28.21 ? 351 GLN A O 1 ATOM 2828 C CB . GLN A 1 343 ? 181.322 38.573 -42.130 1.00 29.45 ? 351 GLN A CB 1 ATOM 2829 C CG . GLN A 1 343 ? 181.489 37.062 -42.056 1.00 32.92 ? 351 GLN A CG 1 ATOM 2830 C CD . GLN A 1 343 ? 180.159 36.345 -41.864 1.00 36.23 ? 351 GLN A CD 1 ATOM 2831 O OE1 . GLN A 1 343 ? 179.423 36.631 -40.917 1.00 38.21 ? 351 GLN A OE1 1 ATOM 2832 N NE2 . GLN A 1 343 ? 179.846 35.409 -42.760 1.00 35.64 ? 351 GLN A NE2 1 ATOM 2833 N N . SER A 1 344 ? 180.406 41.332 -43.989 1.00 26.08 ? 352 SER A N 1 ATOM 2834 C CA . SER A 1 344 ? 180.040 42.735 -43.908 1.00 26.91 ? 352 SER A CA 1 ATOM 2835 C C . SER A 1 344 ? 178.828 43.009 -44.812 1.00 25.74 ? 352 SER A C 1 ATOM 2836 O O . SER A 1 344 ? 178.151 44.028 -44.677 1.00 26.16 ? 352 SER A O 1 ATOM 2837 C CB . SER A 1 344 ? 181.242 43.591 -44.329 1.00 28.02 ? 352 SER A CB 1 ATOM 2838 O OG . SER A 1 344 ? 180.975 44.973 -44.190 1.00 32.18 ? 352 SER A OG 1 ATOM 2839 N N . ALA A 1 345 ? 178.546 42.072 -45.713 1.00 24.34 ? 353 ALA A N 1 ATOM 2840 C CA . ALA A 1 345 ? 177.438 42.199 -46.658 1.00 23.04 ? 353 ALA A CA 1 ATOM 2841 C C . ALA A 1 345 ? 176.082 41.781 -46.107 1.00 22.31 ? 353 ALA A C 1 ATOM 2842 O O . ALA A 1 345 ? 175.990 40.998 -45.161 1.00 23.64 ? 353 ALA A O 1 ATOM 2843 C CB . ALA A 1 345 ? 177.737 41.391 -47.921 1.00 22.01 ? 353 ALA A CB 1 ATOM 2844 N N . PRO A 1 346 ? 175.002 42.310 -46.698 1.00 20.84 ? 354 PRO A N 1 ATOM 2845 C CA . PRO A 1 346 ? 173.669 41.944 -46.222 1.00 20.16 ? 354 PRO A CA 1 ATOM 2846 C C . PRO A 1 346 ? 173.235 40.575 -46.719 1.00 19.26 ? 354 PRO A C 1 ATOM 2847 O O . PRO A 1 346 ? 173.887 39.972 -47.566 1.00 18.05 ? 354 PRO A O 1 ATOM 2848 C CB . PRO A 1 346 ? 172.782 43.044 -46.801 1.00 18.77 ? 354 PRO A CB 1 ATOM 2849 C CG . PRO A 1 346 ? 173.471 43.386 -48.078 1.00 18.57 ? 354 PRO A CG 1 ATOM 2850 C CD . PRO A 1 346 ? 174.927 43.425 -47.661 1.00 18.63 ? 354 PRO A CD 1 ATOM 2851 N N . VAL A 1 347 ? 172.140 40.083 -46.154 1.00 19.24 ? 355 VAL A N 1 ATOM 2852 C CA . VAL A 1 347 ? 171.545 38.828 -46.585 1.00 18.92 ? 355 VAL A CA 1 ATOM 2853 C C . VAL A 1 347 ? 170.465 39.325 -47.546 1.00 19.90 ? 355 VAL A C 1 ATOM 2854 O O . VAL A 1 347 ? 169.745 40.280 -47.214 1.00 20.45 ? 355 VAL A O 1 ATOM 2855 C CB . VAL A 1 347 ? 170.848 38.081 -45.425 1.00 19.34 ? 355 VAL A CB 1 ATOM 2856 C CG1 . VAL A 1 347 ? 169.916 36.998 -45.987 1.00 16.46 ? 355 VAL A CG1 1 ATOM 2857 C CG2 . VAL A 1 347 ? 171.882 37.472 -44.506 1.00 15.14 ? 355 VAL A CG2 1 ATOM 2858 N N . TYR A 1 348 ? 170.362 38.721 -48.729 1.00 18.79 ? 356 TYR A N 1 ATOM 2859 C CA . TYR A 1 348 ? 169.347 39.141 -49.690 1.00 16.80 ? 356 TYR A CA 1 ATOM 2860 C C . TYR A 1 348 ? 168.241 38.117 -49.689 1.00 16.57 ? 356 TYR A C 1 ATOM 2861 O O . TYR A 1 348 ? 168.501 36.919 -49.805 1.00 16.23 ? 356 TYR A O 1 ATOM 2862 C CB . TYR A 1 348 ? 169.922 39.245 -51.101 1.00 16.85 ? 356 TYR A CB 1 ATOM 2863 C CG . TYR A 1 348 ? 170.979 40.310 -51.271 1.00 17.19 ? 356 TYR A CG 1 ATOM 2864 C CD1 . TYR A 1 348 ? 172.322 40.046 -50.984 1.00 16.34 ? 356 TYR A CD1 1 ATOM 2865 C CD2 . TYR A 1 348 ? 170.639 41.590 -51.710 1.00 16.43 ? 356 TYR A CD2 1 ATOM 2866 C CE1 . TYR A 1 348 ? 173.296 41.028 -51.132 1.00 15.23 ? 356 TYR A CE1 1 ATOM 2867 C CE2 . TYR A 1 348 ? 171.610 42.581 -51.860 1.00 15.86 ? 356 TYR A CE2 1 ATOM 2868 C CZ . TYR A 1 348 ? 172.931 42.291 -51.568 1.00 15.09 ? 356 TYR A CZ 1 ATOM 2869 O OH . TYR A 1 348 ? 173.885 43.269 -51.706 1.00 16.60 ? 356 TYR A OH 1 ATOM 2870 N N . ILE A 1 349 ? 167.006 38.587 -49.557 1.00 17.50 ? 357 ILE A N 1 ATOM 2871 C CA . ILE A 1 349 ? 165.845 37.699 -49.540 1.00 17.55 ? 357 ILE A CA 1 ATOM 2872 C C . ILE A 1 349 ? 164.773 38.147 -50.531 1.00 19.00 ? 357 ILE A C 1 ATOM 2873 O O . ILE A 1 349 ? 164.416 39.326 -50.559 1.00 19.73 ? 357 ILE A O 1 ATOM 2874 C CB . ILE A 1 349 ? 165.200 37.657 -48.130 1.00 14.94 ? 357 ILE A CB 1 ATOM 2875 C CG1 . ILE A 1 349 ? 166.111 36.916 -47.152 1.00 13.44 ? 357 ILE A CG1 1 ATOM 2876 C CG2 . ILE A 1 349 ? 163.817 37.001 -48.211 1.00 13.43 ? 357 ILE A CG2 1 ATOM 2877 C CD1 . ILE A 1 349 ? 165.605 36.912 -45.727 1.00 12.16 ? 357 ILE A CD1 1 ATOM 2878 N N . THR A 1 350 ? 164.271 37.230 -51.356 1.00 19.16 ? 358 THR A N 1 ATOM 2879 C CA . THR A 1 350 ? 163.202 37.607 -52.268 1.00 20.46 ? 358 THR A CA 1 ATOM 2880 C C . THR A 1 350 ? 161.924 36.867 -51.829 1.00 21.26 ? 358 THR A C 1 ATOM 2881 O O . THR A 1 350 ? 161.929 35.634 -51.702 1.00 21.96 ? 358 THR A O 1 ATOM 2882 C CB . THR A 1 350 ? 163.571 37.308 -53.772 1.00 21.05 ? 358 THR A CB 1 ATOM 2883 O OG1 . THR A 1 350 ? 162.813 36.202 -54.257 1.00 21.77 ? 358 THR A OG1 1 ATOM 2884 C CG2 . THR A 1 350 ? 165.055 37.009 -53.929 1.00 19.79 ? 358 THR A CG2 1 ATOM 2885 N N . ILE A 1 351 ? 160.863 37.628 -51.531 1.00 20.21 ? 359 ILE A N 1 ATOM 2886 C CA . ILE A 1 351 ? 159.571 37.065 -51.118 1.00 20.24 ? 359 ILE A CA 1 ATOM 2887 C C . ILE A 1 351 ? 158.449 37.648 -51.971 1.00 19.80 ? 359 ILE A C 1 ATOM 2888 O O . ILE A 1 351 ? 157.538 38.290 -51.454 1.00 19.11 ? 359 ILE A O 1 ATOM 2889 C CB . ILE A 1 351 ? 159.171 37.367 -49.628 1.00 19.78 ? 359 ILE A CB 1 ATOM 2890 C CG1 . ILE A 1 351 ? 159.327 38.850 -49.326 1.00 20.80 ? 359 ILE A CG1 1 ATOM 2891 C CG2 . ILE A 1 351 ? 159.929 36.496 -48.672 1.00 20.85 ? 359 ILE A CG2 1 ATOM 2892 C CD1 . ILE A 1 351 ? 160.730 39.333 -49.287 1.00 24.82 ? 359 ILE A CD1 1 ATOM 2893 N N . GLY A 1 352 ? 158.519 37.443 -53.278 1.00 21.21 ? 360 GLY A N 1 ATOM 2894 C CA . GLY A 1 352 ? 157.472 37.951 -54.143 1.00 21.16 ? 360 GLY A CA 1 ATOM 2895 C C . GLY A 1 352 ? 156.508 36.822 -54.440 1.00 22.34 ? 360 GLY A C 1 ATOM 2896 O O . GLY A 1 352 ? 155.899 36.781 -55.511 1.00 23.30 ? 360 GLY A O 1 ATOM 2897 N N . ASP A 1 353 ? 156.355 35.914 -53.477 1.00 22.30 ? 361 ASP A N 1 ATOM 2898 C CA . ASP A 1 353 ? 155.499 34.742 -53.637 1.00 21.89 ? 361 ASP A CA 1 ATOM 2899 C C . ASP A 1 353 ? 154.200 34.809 -52.855 1.00 21.16 ? 361 ASP A C 1 ATOM 2900 O O . ASP A 1 353 ? 153.702 33.779 -52.401 1.00 21.63 ? 361 ASP A O 1 ATOM 2901 C CB . ASP A 1 353 ? 156.271 33.484 -53.215 1.00 22.84 ? 361 ASP A CB 1 ATOM 2902 C CG . ASP A 1 353 ? 156.582 33.462 -51.725 1.00 24.28 ? 361 ASP A CG 1 ATOM 2903 O OD1 . ASP A 1 353 ? 156.792 34.550 -51.151 1.00 24.57 ? 361 ASP A OD1 1 ATOM 2904 O OD2 . ASP A 1 353 ? 156.631 32.361 -51.129 1.00 23.99 ? 361 ASP A OD2 1 ATOM 2905 N N . ALA A 1 354 ? 153.647 36.007 -52.699 1.00 20.95 ? 362 ALA A N 1 ATOM 2906 C CA . ALA A 1 354 ? 152.394 36.170 -51.960 1.00 20.12 ? 362 ALA A CA 1 ATOM 2907 C C . ALA A 1 354 ? 151.164 35.711 -52.761 1.00 20.79 ? 362 ALA A C 1 ATOM 2908 O O . ALA A 1 354 ? 150.088 35.500 -52.189 1.00 20.56 ? 362 ALA A O 1 ATOM 2909 C CB . ALA A 1 354 ? 152.228 37.617 -51.528 1.00 17.78 ? 362 ALA A CB 1 ATOM 2910 N N . GLY A 1 355 ? 151.310 35.565 -54.078 1.00 20.27 ? 363 GLY A N 1 ATOM 2911 C CA . GLY A 1 355 ? 150.183 35.107 -54.870 1.00 21.34 ? 363 GLY A CA 1 ATOM 2912 C C . GLY A 1 355 ? 149.981 35.644 -56.279 1.00 22.33 ? 363 GLY A C 1 ATOM 2913 O O . GLY A 1 355 ? 149.646 34.881 -57.197 1.00 21.47 ? 363 GLY A O 1 ATOM 2914 N N . ASN A 1 356 ? 150.192 36.942 -56.463 1.00 23.21 ? 364 ASN A N 1 ATOM 2915 C CA . ASN A 1 356 ? 149.984 37.587 -57.761 1.00 24.10 ? 364 ASN A CA 1 ATOM 2916 C C . ASN A 1 356 ? 148.690 37.073 -58.415 1.00 24.33 ? 364 ASN A C 1 ATOM 2917 O O . ASN A 1 356 ? 147.640 37.058 -57.767 1.00 22.42 ? 364 ASN A O 1 ATOM 2918 C CB . ASN A 1 356 ? 151.220 37.419 -58.686 1.00 24.35 ? 364 ASN A CB 1 ATOM 2919 C CG . ASN A 1 356 ? 151.509 35.972 -59.076 1.00 24.11 ? 364 ASN A CG 1 ATOM 2920 O OD1 . ASN A 1 356 ? 150.948 35.446 -60.040 1.00 24.27 ? 364 ASN A OD1 1 ATOM 2921 N ND2 . ASN A 1 356 ? 152.401 35.331 -58.334 1.00 23.71 ? 364 ASN A ND2 1 ATOM 2922 N N . TYR A 1 357 ? 148.736 36.675 -59.681 1.00 25.40 ? 365 TYR A N 1 ATOM 2923 C CA . TYR A 1 357 ? 147.526 36.176 -60.318 1.00 27.15 ? 365 TYR A CA 1 ATOM 2924 C C . TYR A 1 357 ? 147.480 34.650 -60.358 1.00 27.81 ? 365 TYR A C 1 ATOM 2925 O O . TYR A 1 357 ? 146.864 34.066 -61.249 1.00 29.05 ? 365 TYR A O 1 ATOM 2926 C CB . TYR A 1 357 ? 147.371 36.754 -61.730 1.00 27.00 ? 365 TYR A CB 1 ATOM 2927 C CG . TYR A 1 357 ? 148.620 36.682 -62.570 1.00 27.98 ? 365 TYR A CG 1 ATOM 2928 C CD1 . TYR A 1 357 ? 149.619 37.651 -62.457 1.00 27.76 ? 365 TYR A CD1 1 ATOM 2929 C CD2 . TYR A 1 357 ? 148.814 35.634 -63.468 1.00 28.44 ? 365 TYR A CD2 1 ATOM 2930 C CE1 . TYR A 1 357 ? 150.778 37.579 -63.217 1.00 28.28 ? 365 TYR A CE1 1 ATOM 2931 C CE2 . TYR A 1 357 ? 149.972 35.551 -64.232 1.00 29.37 ? 365 TYR A CE2 1 ATOM 2932 C CZ . TYR A 1 357 ? 150.949 36.525 -64.099 1.00 28.94 ? 365 TYR A CZ 1 ATOM 2933 O OH . TYR A 1 357 ? 152.104 36.433 -64.838 1.00 32.22 ? 365 TYR A OH 1 ATOM 2934 N N . GLY A 1 358 ? 148.143 34.013 -59.392 1.00 27.97 ? 366 GLY A N 1 ATOM 2935 C CA . GLY A 1 358 ? 148.126 32.563 -59.308 1.00 26.73 ? 366 GLY A CA 1 ATOM 2936 C C . GLY A 1 358 ? 149.266 31.779 -59.933 1.00 27.49 ? 366 GLY A C 1 ATOM 2937 O O . GLY A 1 358 ? 149.244 30.546 -59.905 1.00 27.18 ? 366 GLY A O 1 ATOM 2938 N N . VAL A 1 359 ? 150.251 32.461 -60.507 1.00 27.63 ? 367 VAL A N 1 ATOM 2939 C CA . VAL A 1 359 ? 151.376 31.761 -61.114 1.00 27.82 ? 367 VAL A CA 1 ATOM 2940 C C . VAL A 1 359 ? 152.601 31.827 -60.211 1.00 28.66 ? 367 VAL A C 1 ATOM 2941 O O . VAL A 1 359 ? 152.875 32.857 -59.592 1.00 29.97 ? 367 VAL A O 1 ATOM 2942 C CB . VAL A 1 359 ? 151.731 32.344 -62.490 1.00 27.99 ? 367 VAL A CB 1 ATOM 2943 C CG1 . VAL A 1 359 ? 152.914 31.590 -63.084 1.00 28.61 ? 367 VAL A CG1 1 ATOM 2944 C CG2 . VAL A 1 359 ? 150.535 32.239 -63.413 1.00 28.43 ? 367 VAL A CG2 1 ATOM 2945 N N . ILE A 1 360 ? 153.333 30.720 -60.143 1.00 28.21 ? 368 ILE A N 1 ATOM 2946 C CA . ILE A 1 360 ? 154.520 30.629 -59.307 1.00 28.67 ? 368 ILE A CA 1 ATOM 2947 C C . ILE A 1 360 ? 155.729 30.341 -60.210 1.00 28.68 ? 368 ILE A C 1 ATOM 2948 O O . ILE A 1 360 ? 155.606 29.607 -61.185 1.00 29.05 ? 368 ILE A O 1 ATOM 2949 C CB . ILE A 1 360 ? 154.310 29.503 -58.253 1.00 29.44 ? 368 ILE A CB 1 ATOM 2950 C CG1 . ILE A 1 360 ? 155.098 29.804 -56.981 1.00 32.15 ? 368 ILE A CG1 1 ATOM 2951 C CG2 . ILE A 1 360 ? 154.723 28.159 -58.825 1.00 28.64 ? 368 ILE A CG2 1 ATOM 2952 C CD1 . ILE A 1 360 ? 156.584 29.677 -57.151 1.00 36.64 ? 368 ILE A CD1 1 ATOM 2953 N N . ASP A 1 361 ? 156.882 30.943 -59.923 1.00 28.74 ? 369 ASP A N 1 ATOM 2954 C CA . ASP A 1 361 ? 158.073 30.699 -60.742 1.00 29.74 ? 369 ASP A CA 1 ATOM 2955 C C . ASP A 1 361 ? 158.804 29.480 -60.202 1.00 30.64 ? 369 ASP A C 1 ATOM 2956 O O . ASP A 1 361 ? 159.352 29.522 -59.105 1.00 31.63 ? 369 ASP A O 1 ATOM 2957 C CB . ASP A 1 361 ? 159.033 31.894 -60.716 1.00 30.04 ? 369 ASP A CB 1 ATOM 2958 C CG . ASP A 1 361 ? 158.487 33.105 -61.437 1.00 29.98 ? 369 ASP A CG 1 ATOM 2959 O OD1 . ASP A 1 361 ? 157.840 32.935 -62.489 1.00 31.24 ? 369 ASP A OD1 1 ATOM 2960 O OD2 . ASP A 1 361 ? 158.721 34.232 -60.958 1.00 30.77 ? 369 ASP A OD2 1 ATOM 2961 N N . SER A 1 362 ? 158.831 28.402 -60.974 1.00 31.46 ? 370 SER A N 1 ATOM 2962 C CA . SER A 1 362 ? 159.481 27.184 -60.515 1.00 31.73 ? 370 SER A CA 1 ATOM 2963 C C . SER A 1 362 ? 160.822 26.891 -61.167 1.00 32.35 ? 370 SER A C 1 ATOM 2964 O O . SER A 1 362 ? 161.622 26.142 -60.611 1.00 33.92 ? 370 SER A O 1 ATOM 2965 C CB . SER A 1 362 ? 158.537 26.002 -60.706 1.00 30.34 ? 370 SER A CB 1 ATOM 2966 O OG . SER A 1 362 ? 157.926 26.076 -61.980 1.00 32.74 ? 370 SER A OG 1 ATOM 2967 N N . ASN A 1 363 ? 161.074 27.476 -62.335 1.00 33.26 ? 371 ASN A N 1 ATOM 2968 C CA . ASN A 1 363 ? 162.341 27.264 -63.037 1.00 35.02 ? 371 ASN A CA 1 ATOM 2969 C C . ASN A 1 363 ? 163.478 27.933 -62.287 1.00 33.42 ? 371 ASN A C 1 ATOM 2970 O O . ASN A 1 363 ? 163.450 29.143 -62.057 1.00 33.68 ? 371 ASN A O 1 ATOM 2971 C CB . ASN A 1 363 ? 162.302 27.863 -64.443 1.00 40.89 ? 371 ASN A CB 1 ATOM 2972 C CG . ASN A 1 363 ? 161.286 27.197 -65.334 1.00 48.36 ? 371 ASN A CG 1 ATOM 2973 O OD1 . ASN A 1 363 ? 160.099 27.097 -64.992 1.00 52.65 ? 371 ASN A OD1 1 ATOM 2974 N ND2 . ASN A 1 363 ? 161.741 26.739 -66.498 1.00 51.62 ? 371 ASN A ND2 1 ATOM 2975 N N . MET A 1 364 ? 164.487 27.155 -61.923 1.00 31.10 ? 372 MET A N 1 ATOM 2976 C CA . MET A 1 364 ? 165.626 27.707 -61.212 1.00 29.20 ? 372 MET A CA 1 ATOM 2977 C C . MET A 1 364 ? 166.888 27.435 -62.002 1.00 28.58 ? 372 MET A C 1 ATOM 2978 O O . MET A 1 364 ? 166.913 26.563 -62.868 1.00 28.91 ? 372 MET A O 1 ATOM 2979 C CB . MET A 1 364 ? 165.752 27.064 -59.835 1.00 27.72 ? 372 MET A CB 1 ATOM 2980 C CG . MET A 1 364 ? 164.451 26.984 -59.084 1.00 28.50 ? 372 MET A CG 1 ATOM 2981 S SD . MET A 1 364 ? 164.596 26.006 -57.596 1.00 27.77 ? 372 MET A SD 1 ATOM 2982 C CE . MET A 1 364 ? 163.542 26.957 -56.511 1.00 28.13 ? 372 MET A CE 1 ATOM 2983 N N . ILE A 1 365 ? 167.931 28.201 -61.704 1.00 28.31 ? 373 ILE A N 1 ATOM 2984 C CA . ILE A 1 365 ? 169.226 28.026 -62.342 1.00 27.58 ? 373 ILE A CA 1 ATOM 2985 C C . ILE A 1 365 ? 169.821 26.792 -61.661 1.00 28.31 ? 373 ILE A C 1 ATOM 2986 O O . ILE A 1 365 ? 169.977 26.767 -60.441 1.00 28.11 ? 373 ILE A O 1 ATOM 2987 C CB . ILE A 1 365 ? 170.158 29.239 -62.068 1.00 27.34 ? 373 ILE A CB 1 ATOM 2988 C CG1 . ILE A 1 365 ? 169.590 30.517 -62.697 1.00 26.50 ? 373 ILE A CG1 1 ATOM 2989 C CG2 . ILE A 1 365 ? 171.555 28.941 -62.575 1.00 26.92 ? 373 ILE A CG2 1 ATOM 2990 C CD1 . ILE A 1 365 ? 169.529 30.500 -64.200 1.00 26.11 ? 373 ILE A CD1 1 ATOM 2991 N N . GLN A 1 366 ? 170.139 25.767 -62.441 1.00 29.91 ? 374 GLN A N 1 ATOM 2992 C CA . GLN A 1 366 ? 170.711 24.535 -61.897 1.00 30.28 ? 374 GLN A CA 1 ATOM 2993 C C . GLN A 1 366 ? 172.170 24.432 -62.334 1.00 29.38 ? 374 GLN A C 1 ATOM 2994 O O . GLN A 1 366 ? 172.502 24.731 -63.479 1.00 30.82 ? 374 GLN A O 1 ATOM 2995 C CB . GLN A 1 366 ? 169.933 23.330 -62.420 1.00 33.09 ? 374 GLN A CB 1 ATOM 2996 C CG . GLN A 1 366 ? 169.545 22.312 -61.364 1.00 39.17 ? 374 GLN A CG 1 ATOM 2997 C CD . GLN A 1 366 ? 168.522 22.855 -60.389 1.00 41.87 ? 374 GLN A CD 1 ATOM 2998 O OE1 . GLN A 1 366 ? 167.491 23.392 -60.797 1.00 44.70 ? 374 GLN A OE1 1 ATOM 2999 N NE2 . GLN A 1 366 ? 168.797 22.715 -59.092 1.00 44.27 ? 374 GLN A NE2 1 ATOM 3000 N N . PRO A 1 367 ? 173.068 24.016 -61.431 1.00 28.59 ? 375 PRO A N 1 ATOM 3001 C CA . PRO A 1 367 ? 172.803 23.665 -60.034 1.00 27.92 ? 375 PRO A CA 1 ATOM 3002 C C . PRO A 1 367 ? 172.684 24.928 -59.189 1.00 27.27 ? 375 PRO A C 1 ATOM 3003 O O . PRO A 1 367 ? 173.047 26.019 -59.633 1.00 27.07 ? 375 PRO A O 1 ATOM 3004 C CB . PRO A 1 367 ? 174.020 22.825 -59.663 1.00 26.75 ? 375 PRO A CB 1 ATOM 3005 C CG . PRO A 1 367 ? 175.115 23.495 -60.437 1.00 27.30 ? 375 PRO A CG 1 ATOM 3006 C CD . PRO A 1 367 ? 174.479 23.763 -61.784 1.00 27.43 ? 375 PRO A CD 1 ATOM 3007 N N . GLN A 1 368 ? 172.172 24.783 -57.974 1.00 26.32 ? 376 GLN A N 1 ATOM 3008 C CA . GLN A 1 368 ? 172.014 25.927 -57.097 1.00 25.74 ? 376 GLN A CA 1 ATOM 3009 C C . GLN A 1 368 ? 173.372 26.585 -56.845 1.00 25.02 ? 376 GLN A C 1 ATOM 3010 O O . GLN A 1 368 ? 174.305 25.942 -56.373 1.00 25.01 ? 376 GLN A O 1 ATOM 3011 C CB . GLN A 1 368 ? 171.376 25.472 -55.794 1.00 24.42 ? 376 GLN A CB 1 ATOM 3012 C CG . GLN A 1 368 ? 171.237 26.547 -54.753 1.00 28.07 ? 376 GLN A CG 1 ATOM 3013 C CD . GLN A 1 368 ? 170.442 26.063 -53.562 1.00 30.20 ? 376 GLN A CD 1 ATOM 3014 O OE1 . GLN A 1 368 ? 170.427 24.870 -53.262 1.00 33.56 ? 376 GLN A OE1 1 ATOM 3015 N NE2 . GLN A 1 368 ? 169.784 26.982 -52.870 1.00 29.11 ? 376 GLN A NE2 1 ATOM 3016 N N . PRO A 1 369 ? 173.505 27.874 -57.188 1.00 24.52 ? 377 PRO A N 1 ATOM 3017 C CA . PRO A 1 369 ? 174.764 28.598 -56.988 1.00 25.33 ? 377 PRO A CA 1 ATOM 3018 C C . PRO A 1 369 ? 175.137 28.682 -55.517 1.00 25.80 ? 377 PRO A C 1 ATOM 3019 O O . PRO A 1 369 ? 174.273 28.599 -54.645 1.00 25.98 ? 377 PRO A O 1 ATOM 3020 C CB . PRO A 1 369 ? 174.481 29.967 -57.609 1.00 24.64 ? 377 PRO A CB 1 ATOM 3021 C CG . PRO A 1 369 ? 172.999 30.117 -57.429 1.00 25.80 ? 377 PRO A CG 1 ATOM 3022 C CD . PRO A 1 369 ? 172.484 28.749 -57.790 1.00 23.89 ? 377 PRO A CD 1 ATOM 3023 N N . GLU A 1 370 ? 176.427 28.862 -55.252 1.00 27.42 ? 378 GLU A N 1 ATOM 3024 C CA . GLU A 1 370 ? 176.950 28.931 -53.891 1.00 29.86 ? 378 GLU A CA 1 ATOM 3025 C C . GLU A 1 370 ? 176.383 30.072 -53.040 1.00 28.10 ? 378 GLU A C 1 ATOM 3026 O O . GLU A 1 370 ? 176.247 29.927 -51.819 1.00 27.38 ? 378 GLU A O 1 ATOM 3027 C CB . GLU A 1 370 ? 178.480 29.026 -53.927 1.00 34.46 ? 378 GLU A CB 1 ATOM 3028 C CG . GLU A 1 370 ? 179.154 28.158 -55.005 1.00 45.29 ? 378 GLU A CG 1 ATOM 3029 C CD . GLU A 1 370 ? 178.975 28.703 -56.444 1.00 51.66 ? 378 GLU A CD 1 ATOM 3030 O OE1 . GLU A 1 370 ? 179.432 29.839 -56.731 1.00 54.31 ? 378 GLU A OE1 1 ATOM 3031 O OE2 . GLU A 1 370 ? 178.383 27.995 -57.295 1.00 53.08 ? 378 GLU A OE2 1 ATOM 3032 N N . TYR A 1 371 ? 176.038 31.189 -53.677 1.00 26.22 ? 379 TYR A N 1 ATOM 3033 C CA . TYR A 1 371 ? 175.515 32.344 -52.952 1.00 25.47 ? 379 TYR A CA 1 ATOM 3034 C C . TYR A 1 371 ? 174.066 32.187 -52.490 1.00 26.12 ? 379 TYR A C 1 ATOM 3035 O O . TYR A 1 371 ? 173.583 32.965 -51.662 1.00 27.39 ? 379 TYR A O 1 ATOM 3036 C CB . TYR A 1 371 ? 175.676 33.614 -53.803 1.00 24.12 ? 379 TYR A CB 1 ATOM 3037 C CG . TYR A 1 371 ? 174.883 33.632 -55.088 1.00 22.01 ? 379 TYR A CG 1 ATOM 3038 C CD1 . TYR A 1 371 ? 173.518 33.910 -55.089 1.00 23.03 ? 379 TYR A CD1 1 ATOM 3039 C CD2 . TYR A 1 371 ? 175.497 33.370 -56.303 1.00 22.72 ? 379 TYR A CD2 1 ATOM 3040 C CE1 . TYR A 1 371 ? 172.783 33.925 -56.276 1.00 23.54 ? 379 TYR A CE1 1 ATOM 3041 C CE2 . TYR A 1 371 ? 174.776 33.379 -57.492 1.00 23.72 ? 379 TYR A CE2 1 ATOM 3042 C CZ . TYR A 1 371 ? 173.420 33.655 -57.473 1.00 24.21 ? 379 TYR A CZ 1 ATOM 3043 O OH . TYR A 1 371 ? 172.703 33.645 -58.654 1.00 25.15 ? 379 TYR A OH 1 ATOM 3044 N N . SER A 1 372 ? 173.382 31.169 -53.003 1.00 26.35 ? 380 SER A N 1 ATOM 3045 C CA . SER A 1 372 ? 171.989 30.915 -52.634 1.00 26.30 ? 380 SER A CA 1 ATOM 3046 C C . SER A 1 372 ? 171.903 29.937 -51.465 1.00 26.50 ? 380 SER A C 1 ATOM 3047 O O . SER A 1 372 ? 172.302 28.781 -51.594 1.00 28.12 ? 380 SER A O 1 ATOM 3048 C CB . SER A 1 372 ? 171.235 30.339 -53.830 1.00 25.90 ? 380 SER A CB 1 ATOM 3049 O OG . SER A 1 372 ? 169.873 30.128 -53.509 1.00 25.57 ? 380 SER A OG 1 ATOM 3050 N N . ALA A 1 373 ? 171.366 30.385 -50.333 1.00 25.08 ? 381 ALA A N 1 ATOM 3051 C CA . ALA A 1 373 ? 171.272 29.524 -49.157 1.00 24.21 ? 381 ALA A CA 1 ATOM 3052 C C . ALA A 1 373 ? 170.035 28.634 -49.123 1.00 24.67 ? 381 ALA A C 1 ATOM 3053 O O . ALA A 1 373 ? 170.106 27.480 -48.702 1.00 23.63 ? 381 ALA A O 1 ATOM 3054 C CB . ALA A 1 373 ? 171.330 30.366 -47.894 1.00 24.32 ? 381 ALA A CB 1 ATOM 3055 N N . PHE A 1 374 ? 168.902 29.172 -49.553 1.00 24.68 ? 382 PHE A N 1 ATOM 3056 C CA . PHE A 1 374 ? 167.665 28.409 -49.560 1.00 25.35 ? 382 PHE A CA 1 ATOM 3057 C C . PHE A 1 374 ? 166.756 28.995 -50.625 1.00 25.63 ? 382 PHE A C 1 ATOM 3058 O O . PHE A 1 374 ? 166.756 30.203 -50.851 1.00 27.87 ? 382 PHE A O 1 ATOM 3059 C CB . PHE A 1 374 ? 167.013 28.483 -48.179 1.00 28.08 ? 382 PHE A CB 1 ATOM 3060 C CG . PHE A 1 374 ? 165.772 27.653 -48.044 1.00 31.14 ? 382 PHE A CG 1 ATOM 3061 C CD1 . PHE A 1 374 ? 164.557 28.098 -48.555 1.00 33.26 ? 382 PHE A CD1 1 ATOM 3062 C CD2 . PHE A 1 374 ? 165.819 26.414 -47.424 1.00 32.95 ? 382 PHE A CD2 1 ATOM 3063 C CE1 . PHE A 1 374 ? 163.404 27.318 -48.454 1.00 34.51 ? 382 PHE A CE1 1 ATOM 3064 C CE2 . PHE A 1 374 ? 164.672 25.624 -47.318 1.00 34.92 ? 382 PHE A CE2 1 ATOM 3065 C CZ . PHE A 1 374 ? 163.462 26.078 -47.835 1.00 35.28 ? 382 PHE A CZ 1 ATOM 3066 N N . ARG A 1 375 ? 165.998 28.138 -51.295 1.00 24.79 ? 383 ARG A N 1 ATOM 3067 C CA . ARG A 1 375 ? 165.089 28.575 -52.349 1.00 24.52 ? 383 ARG A CA 1 ATOM 3068 C C . ARG A 1 375 ? 163.988 27.545 -52.510 1.00 25.19 ? 383 ARG A C 1 ATOM 3069 O O . ARG A 1 375 ? 164.212 26.349 -52.324 1.00 24.51 ? 383 ARG A O 1 ATOM 3070 C CB . ARG A 1 375 ? 165.833 28.725 -53.685 1.00 23.94 ? 383 ARG A CB 1 ATOM 3071 C CG . ARG A 1 375 ? 166.837 27.612 -53.913 1.00 26.08 ? 383 ARG A CG 1 ATOM 3072 C CD . ARG A 1 375 ? 166.844 27.064 -55.320 1.00 25.56 ? 383 ARG A CD 1 ATOM 3073 N NE . ARG A 1 375 ? 167.923 27.613 -56.130 1.00 26.07 ? 383 ARG A NE 1 ATOM 3074 C CZ . ARG A 1 375 ? 168.454 26.996 -57.183 1.00 26.22 ? 383 ARG A CZ 1 ATOM 3075 N NH1 . ARG A 1 375 ? 168.021 25.800 -57.562 1.00 25.99 ? 383 ARG A NH1 1 ATOM 3076 N NH2 . ARG A 1 375 ? 169.418 27.583 -57.869 1.00 27.91 ? 383 ARG A NH2 1 ATOM 3077 N N . GLU A 1 376 ? 162.794 28.018 -52.848 1.00 26.16 ? 384 GLU A N 1 ATOM 3078 C CA . GLU A 1 376 ? 161.665 27.134 -53.057 1.00 27.62 ? 384 GLU A CA 1 ATOM 3079 C C . GLU A 1 376 ? 160.525 27.846 -53.763 1.00 27.67 ? 384 GLU A C 1 ATOM 3080 O O . GLU A 1 376 ? 160.196 28.991 -53.452 1.00 27.47 ? 384 GLU A O 1 ATOM 3081 C CB . GLU A 1 376 ? 161.159 26.568 -51.734 1.00 27.81 ? 384 GLU A CB 1 ATOM 3082 C CG . GLU A 1 376 ? 160.077 25.529 -51.938 1.00 30.16 ? 384 GLU A CG 1 ATOM 3083 C CD . GLU A 1 376 ? 159.525 24.998 -50.643 1.00 32.36 ? 384 GLU A CD 1 ATOM 3084 O OE1 . GLU A 1 376 ? 160.325 24.640 -49.752 1.00 34.23 ? 384 GLU A OE1 1 ATOM 3085 O OE2 . GLU A 1 376 ? 158.287 24.930 -50.517 1.00 35.46 ? 384 GLU A OE2 1 ATOM 3086 N N . ALA A 1 377 ? 159.920 27.144 -54.711 1.00 28.23 ? 385 ALA A N 1 ATOM 3087 C CA . ALA A 1 377 ? 158.815 27.679 -55.483 1.00 26.72 ? 385 ALA A CA 1 ATOM 3088 C C . ALA A 1 377 ? 157.466 27.411 -54.823 1.00 26.56 ? 385 ALA A C 1 ATOM 3089 O O . ALA A 1 377 ? 156.691 26.587 -55.302 1.00 27.70 ? 385 ALA A O 1 ATOM 3090 C CB . ALA A 1 377 ? 158.835 27.081 -56.880 1.00 25.60 ? 385 ALA A CB 1 ATOM 3091 N N . SER A 1 378 ? 157.186 28.101 -53.725 1.00 25.08 ? 386 SER A N 1 ATOM 3092 C CA . SER A 1 378 ? 155.906 27.946 -53.041 1.00 26.15 ? 386 SER A CA 1 ATOM 3093 C C . SER A 1 378 ? 155.362 29.321 -52.678 1.00 26.74 ? 386 SER A C 1 ATOM 3094 O O . SER A 1 378 ? 156.125 30.282 -52.564 1.00 27.57 ? 386 SER A O 1 ATOM 3095 C CB . SER A 1 378 ? 156.072 27.131 -51.761 1.00 26.16 ? 386 SER A CB 1 ATOM 3096 O OG . SER A 1 378 ? 156.555 25.837 -52.051 1.00 30.54 ? 386 SER A OG 1 ATOM 3097 N N . PHE A 1 379 ? 154.048 29.427 -52.515 1.00 25.90 ? 387 PHE A N 1 ATOM 3098 C CA . PHE A 1 379 ? 153.448 30.699 -52.123 1.00 25.61 ? 387 PHE A CA 1 ATOM 3099 C C . PHE A 1 379 ? 153.551 30.819 -50.607 1.00 25.94 ? 387 PHE A C 1 ATOM 3100 O O . PHE A 1 379 ? 153.480 29.819 -49.888 1.00 25.06 ? 387 PHE A O 1 ATOM 3101 C CB . PHE A 1 379 ? 151.974 30.763 -52.521 1.00 26.44 ? 387 PHE A CB 1 ATOM 3102 C CG . PHE A 1 379 ? 151.748 30.980 -53.983 1.00 28.68 ? 387 PHE A CG 1 ATOM 3103 C CD1 . PHE A 1 379 ? 152.270 32.102 -54.619 1.00 28.04 ? 387 PHE A CD1 1 ATOM 3104 C CD2 . PHE A 1 379 ? 150.993 30.074 -54.729 1.00 29.10 ? 387 PHE A CD2 1 ATOM 3105 C CE1 . PHE A 1 379 ? 152.044 32.321 -55.979 1.00 28.31 ? 387 PHE A CE1 1 ATOM 3106 C CE2 . PHE A 1 379 ? 150.762 30.287 -56.087 1.00 28.25 ? 387 PHE A CE2 1 ATOM 3107 C CZ . PHE A 1 379 ? 151.288 31.414 -56.710 1.00 28.29 ? 387 PHE A CZ 1 ATOM 3108 N N . GLY A 1 380 ? 153.713 32.044 -50.122 1.00 25.29 ? 388 GLY A N 1 ATOM 3109 C CA . GLY A 1 380 ? 153.817 32.255 -48.693 1.00 25.48 ? 388 GLY A CA 1 ATOM 3110 C C . GLY A 1 380 ? 154.122 33.702 -48.380 1.00 25.98 ? 388 GLY A C 1 ATOM 3111 O O . GLY A 1 380 ? 153.980 34.579 -49.238 1.00 27.54 ? 388 GLY A O 1 ATOM 3112 N N . HIS A 1 381 ? 154.533 33.960 -47.146 1.00 25.10 ? 389 HIS A N 1 ATOM 3113 C CA . HIS A 1 381 ? 154.875 35.310 -46.721 1.00 24.28 ? 389 HIS A CA 1 ATOM 3114 C C . HIS A 1 381 ? 156.008 35.172 -45.725 1.00 23.46 ? 389 HIS A C 1 ATOM 3115 O O . HIS A 1 381 ? 156.445 34.066 -45.445 1.00 24.31 ? 389 HIS A O 1 ATOM 3116 C CB . HIS A 1 381 ? 153.669 35.992 -46.071 1.00 24.82 ? 389 HIS A CB 1 ATOM 3117 C CG . HIS A 1 381 ? 153.190 35.313 -44.826 1.00 27.33 ? 389 HIS A CG 1 ATOM 3118 N ND1 . HIS A 1 381 ? 153.446 35.804 -43.564 1.00 28.15 ? 389 HIS A ND1 1 ATOM 3119 C CD2 . HIS A 1 381 ? 152.497 34.163 -44.650 1.00 28.41 ? 389 HIS A CD2 1 ATOM 3120 C CE1 . HIS A 1 381 ? 152.932 34.986 -42.662 1.00 28.14 ? 389 HIS A CE1 1 ATOM 3121 N NE2 . HIS A 1 381 ? 152.353 33.982 -43.295 1.00 30.35 ? 389 HIS A NE2 1 ATOM 3122 N N . GLY A 1 382 ? 156.485 36.284 -45.186 1.00 23.32 ? 390 GLY A N 1 ATOM 3123 C CA . GLY A 1 382 ? 157.578 36.211 -44.235 1.00 22.11 ? 390 GLY A CA 1 ATOM 3124 C C . GLY A 1 382 ? 157.366 37.072 -43.008 1.00 22.43 ? 390 GLY A C 1 ATOM 3125 O O . GLY A 1 382 ? 156.474 37.917 -42.969 1.00 21.37 ? 390 GLY A O 1 ATOM 3126 N N . MET A 1 383 ? 158.190 36.840 -41.996 1.00 22.68 ? 391 MET A N 1 ATOM 3127 C CA . MET A 1 383 ? 158.119 37.592 -40.759 1.00 24.48 ? 391 MET A CA 1 ATOM 3128 C C . MET A 1 383 ? 159.540 37.902 -40.319 1.00 24.70 ? 391 MET A C 1 ATOM 3129 O O . MET A 1 383 ? 160.417 37.032 -40.334 1.00 25.36 ? 391 MET A O 1 ATOM 3130 C CB . MET A 1 383 ? 157.422 36.775 -39.671 1.00 28.33 ? 391 MET A CB 1 ATOM 3131 C CG . MET A 1 383 ? 155.985 36.358 -39.987 1.00 34.33 ? 391 MET A CG 1 ATOM 3132 S SD . MET A 1 383 ? 154.785 37.719 -39.891 1.00 40.80 ? 391 MET A SD 1 ATOM 3133 C CE . MET A 1 383 ? 155.163 38.397 -38.241 1.00 36.33 ? 391 MET A CE 1 ATOM 3134 N N . PHE A 1 384 ? 159.767 39.156 -39.953 1.00 23.73 ? 392 PHE A N 1 ATOM 3135 C CA . PHE A 1 384 ? 161.069 39.602 -39.481 1.00 23.39 ? 392 PHE A CA 1 ATOM 3136 C C . PHE A 1 384 ? 160.780 40.074 -38.063 1.00 24.28 ? 392 PHE A C 1 ATOM 3137 O O . PHE A 1 384 ? 160.248 41.169 -37.858 1.00 25.91 ? 392 PHE A O 1 ATOM 3138 C CB . PHE A 1 384 ? 161.582 40.764 -40.330 1.00 21.75 ? 392 PHE A CB 1 ATOM 3139 C CG . PHE A 1 384 ? 163.026 41.080 -40.101 1.00 21.20 ? 392 PHE A CG 1 ATOM 3140 C CD1 . PHE A 1 384 ? 164.009 40.179 -40.493 1.00 20.21 ? 392 PHE A CD1 1 ATOM 3141 C CD2 . PHE A 1 384 ? 163.409 42.268 -39.479 1.00 20.68 ? 392 PHE A CD2 1 ATOM 3142 C CE1 . PHE A 1 384 ? 165.354 40.447 -40.274 1.00 20.70 ? 392 PHE A CE1 1 ATOM 3143 C CE2 . PHE A 1 384 ? 164.758 42.551 -39.253 1.00 21.03 ? 392 PHE A CE2 1 ATOM 3144 C CZ . PHE A 1 384 ? 165.733 41.634 -39.654 1.00 21.71 ? 392 PHE A CZ 1 ATOM 3145 N N . ASP A 1 385 ? 161.120 39.240 -37.090 1.00 23.75 ? 393 ASP A N 1 ATOM 3146 C CA . ASP A 1 385 ? 160.845 39.534 -35.697 1.00 24.20 ? 393 ASP A CA 1 ATOM 3147 C C . ASP A 1 385 ? 162.095 40.002 -34.958 1.00 24.51 ? 393 ASP A C 1 ATOM 3148 O O . ASP A 1 385 ? 163.004 39.212 -34.691 1.00 25.56 ? 393 ASP A O 1 ATOM 3149 C CB . ASP A 1 385 ? 160.257 38.264 -35.070 1.00 26.79 ? 393 ASP A CB 1 ATOM 3150 C CG . ASP A 1 385 ? 159.636 38.501 -33.710 1.00 30.65 ? 393 ASP A CG 1 ATOM 3151 O OD1 . ASP A 1 385 ? 158.928 39.517 -33.541 1.00 33.25 ? 393 ASP A OD1 1 ATOM 3152 O OD2 . ASP A 1 385 ? 159.848 37.654 -32.812 1.00 32.90 ? 393 ASP A OD2 1 ATOM 3153 N N . ILE A 1 386 ? 162.148 41.293 -34.637 1.00 23.98 ? 394 ILE A N 1 ATOM 3154 C CA . ILE A 1 386 ? 163.297 41.860 -33.923 1.00 24.80 ? 394 ILE A CA 1 ATOM 3155 C C . ILE A 1 386 ? 163.174 41.658 -32.410 1.00 27.41 ? 394 ILE A C 1 ATOM 3156 O O . ILE A 1 386 ? 162.154 42.014 -31.808 1.00 28.08 ? 394 ILE A O 1 ATOM 3157 C CB . ILE A 1 386 ? 163.436 43.367 -34.205 1.00 22.67 ? 394 ILE A CB 1 ATOM 3158 C CG1 . ILE A 1 386 ? 163.688 43.590 -35.693 1.00 21.71 ? 394 ILE A CG1 1 ATOM 3159 C CG2 . ILE A 1 386 ? 164.591 43.952 -33.401 1.00 22.17 ? 394 ILE A CG2 1 ATOM 3160 C CD1 . ILE A 1 386 ? 163.642 45.044 -36.111 1.00 20.20 ? 394 ILE A CD1 1 ATOM 3161 N N . LYS A 1 387 ? 164.220 41.092 -31.805 1.00 29.71 ? 395 LYS A N 1 ATOM 3162 C CA . LYS A 1 387 ? 164.262 40.824 -30.363 1.00 30.27 ? 395 LYS A CA 1 ATOM 3163 C C . LYS A 1 387 ? 165.072 41.876 -29.601 1.00 30.37 ? 395 LYS A C 1 ATOM 3164 O O . LYS A 1 387 ? 164.536 42.590 -28.756 1.00 30.34 ? 395 LYS A O 1 ATOM 3165 C CB . LYS A 1 387 ? 164.876 39.447 -30.117 1.00 30.98 ? 395 LYS A CB 1 ATOM 3166 C CG . LYS A 1 387 ? 164.140 38.304 -30.793 1.00 32.79 ? 395 LYS A CG 1 ATOM 3167 C CD . LYS A 1 387 ? 162.770 38.099 -30.177 1.00 35.29 ? 395 LYS A CD 1 ATOM 3168 C CE . LYS A 1 387 ? 162.112 36.832 -30.695 1.00 36.66 ? 395 LYS A CE 1 ATOM 3169 N NZ . LYS A 1 387 ? 160.821 36.598 -29.988 1.00 38.48 ? 395 LYS A NZ 1 ATOM 3170 N N . ASN A 1 388 ? 166.373 41.934 -29.879 1.00 32.06 ? 396 ASN A N 1 ATOM 3171 C CA . ASN A 1 388 ? 167.266 42.905 -29.245 1.00 33.18 ? 396 ASN A CA 1 ATOM 3172 C C . ASN A 1 388 ? 168.013 43.597 -30.377 1.00 32.04 ? 396 ASN A C 1 ATOM 3173 O O . ASN A 1 388 ? 167.691 43.408 -31.549 1.00 32.65 ? 396 ASN A O 1 ATOM 3174 C CB . ASN A 1 388 ? 168.336 42.261 -28.337 1.00 35.47 ? 396 ASN A CB 1 ATOM 3175 C CG . ASN A 1 388 ? 168.013 40.845 -27.913 1.00 38.74 ? 396 ASN A CG 1 ATOM 3176 O OD1 . ASN A 1 388 ? 167.164 40.606 -27.054 1.00 42.70 ? 396 ASN A OD1 1 ATOM 3177 N ND2 . ASN A 1 388 ? 168.724 39.904 -28.527 1.00 41.87 ? 396 ASN A ND2 1 ATOM 3178 N N . ARG A 1 389 ? 169.027 44.377 -30.010 1.00 30.14 ? 397 ARG A N 1 ATOM 3179 C CA . ARG A 1 389 ? 169.856 45.099 -30.966 1.00 27.80 ? 397 ARG A CA 1 ATOM 3180 C C . ARG A 1 389 ? 170.814 44.108 -31.613 1.00 26.68 ? 397 ARG A C 1 ATOM 3181 O O . ARG A 1 389 ? 171.508 44.434 -32.569 1.00 26.69 ? 397 ARG A O 1 ATOM 3182 C CB . ARG A 1 389 ? 170.690 46.165 -30.252 1.00 28.01 ? 397 ARG A CB 1 ATOM 3183 C CG . ARG A 1 389 ? 171.984 45.606 -29.639 1.00 27.49 ? 397 ARG A CG 1 ATOM 3184 C CD . ARG A 1 389 ? 172.712 46.630 -28.774 1.00 27.50 ? 397 ARG A CD 1 ATOM 3185 N NE . ARG A 1 389 ? 171.957 46.920 -27.561 1.00 28.23 ? 397 ARG A NE 1 ATOM 3186 C CZ . ARG A 1 389 ? 172.403 47.658 -26.551 1.00 28.07 ? 397 ARG A CZ 1 ATOM 3187 N NH1 . ARG A 1 389 ? 173.614 48.196 -26.596 1.00 28.39 ? 397 ARG A NH1 1 ATOM 3188 N NH2 . ARG A 1 389 ? 171.637 47.850 -25.487 1.00 26.38 ? 397 ARG A NH2 1 ATOM 3189 N N . THR A 1 390 ? 170.870 42.900 -31.077 1.00 24.95 ? 398 THR A N 1 ATOM 3190 C CA . THR A 1 390 ? 171.776 41.913 -31.624 1.00 24.41 ? 398 THR A CA 1 ATOM 3191 C C . THR A 1 390 ? 171.070 40.820 -32.418 1.00 25.22 ? 398 THR A C 1 ATOM 3192 O O . THR A 1 390 ? 171.578 40.359 -33.446 1.00 24.65 ? 398 THR A O 1 ATOM 3193 C CB . THR A 1 390 ? 172.597 41.250 -30.497 1.00 23.91 ? 398 THR A CB 1 ATOM 3194 O OG1 . THR A 1 390 ? 171.707 40.631 -29.560 1.00 24.22 ? 398 THR A OG1 1 ATOM 3195 C CG2 . THR A 1 390 ? 173.437 42.284 -29.775 1.00 19.43 ? 398 THR A CG2 1 ATOM 3196 N N . HIS A 1 391 ? 169.892 40.422 -31.949 1.00 25.95 ? 399 HIS A N 1 ATOM 3197 C CA . HIS A 1 391 ? 169.150 39.349 -32.595 1.00 26.63 ? 399 HIS A CA 1 ATOM 3198 C C . HIS A 1 391 ? 167.823 39.704 -33.248 1.00 26.57 ? 399 HIS A C 1 ATOM 3199 O O . HIS A 1 391 ? 167.042 40.491 -32.716 1.00 27.73 ? 399 HIS A O 1 ATOM 3200 C CB . HIS A 1 391 ? 168.893 38.226 -31.586 1.00 26.86 ? 399 HIS A CB 1 ATOM 3201 C CG . HIS A 1 391 ? 170.136 37.548 -31.108 1.00 28.06 ? 399 HIS A CG 1 ATOM 3202 N ND1 . HIS A 1 391 ? 170.364 36.201 -31.290 1.00 28.55 ? 399 HIS A ND1 1 ATOM 3203 C CD2 . HIS A 1 391 ? 171.226 38.033 -30.470 1.00 27.37 ? 399 HIS A CD2 1 ATOM 3204 C CE1 . HIS A 1 391 ? 171.544 35.885 -30.787 1.00 30.33 ? 399 HIS A CE1 1 ATOM 3205 N NE2 . HIS A 1 391 ? 172.088 36.980 -30.284 1.00 29.95 ? 399 HIS A NE2 1 ATOM 3206 N N . ALA A 1 392 ? 167.575 39.082 -34.397 1.00 26.36 ? 400 ALA A N 1 ATOM 3207 C CA . ALA A 1 392 ? 166.335 39.253 -35.147 1.00 26.07 ? 400 ALA A CA 1 ATOM 3208 C C . ALA A 1 392 ? 166.054 37.895 -35.770 1.00 25.23 ? 400 ALA A C 1 ATOM 3209 O O . ALA A 1 392 ? 166.951 37.287 -36.356 1.00 24.27 ? 400 ALA A O 1 ATOM 3210 C CB . ALA A 1 392 ? 166.499 40.309 -36.226 1.00 25.52 ? 400 ALA A CB 1 ATOM 3211 N N . HIS A 1 393 ? 164.822 37.413 -35.623 1.00 25.07 ? 401 HIS A N 1 ATOM 3212 C CA . HIS A 1 393 ? 164.450 36.114 -36.166 1.00 25.88 ? 401 HIS A CA 1 ATOM 3213 C C . HIS A 1 393 ? 163.541 36.249 -37.376 1.00 25.15 ? 401 HIS A C 1 ATOM 3214 O O . HIS A 1 393 ? 162.476 36.866 -37.304 1.00 24.12 ? 401 HIS A O 1 ATOM 3215 C CB . HIS A 1 393 ? 163.761 35.265 -35.092 1.00 29.90 ? 401 HIS A CB 1 ATOM 3216 C CG . HIS A 1 393 ? 163.490 33.854 -35.516 1.00 36.32 ? 401 HIS A CG 1 ATOM 3217 N ND1 . HIS A 1 393 ? 162.215 33.359 -35.697 1.00 39.11 ? 401 HIS A ND1 1 ATOM 3218 C CD2 . HIS A 1 393 ? 164.335 32.834 -35.810 1.00 38.42 ? 401 HIS A CD2 1 ATOM 3219 C CE1 . HIS A 1 393 ? 162.287 32.097 -36.086 1.00 40.16 ? 401 HIS A CE1 1 ATOM 3220 N NE2 . HIS A 1 393 ? 163.561 31.754 -36.163 1.00 39.97 ? 401 HIS A NE2 1 ATOM 3221 N N . PHE A 1 394 ? 163.980 35.669 -38.491 1.00 24.60 ? 402 PHE A N 1 ATOM 3222 C CA . PHE A 1 394 ? 163.223 35.696 -39.738 1.00 24.41 ? 402 PHE A CA 1 ATOM 3223 C C . PHE A 1 394 ? 162.635 34.327 -40.002 1.00 25.41 ? 402 PHE A C 1 ATOM 3224 O O . PHE A 1 394 ? 163.296 33.310 -39.783 1.00 26.34 ? 402 PHE A O 1 ATOM 3225 C CB . PHE A 1 394 ? 164.120 36.050 -40.925 1.00 22.38 ? 402 PHE A CB 1 ATOM 3226 C CG . PHE A 1 394 ? 163.405 36.008 -42.247 1.00 22.45 ? 402 PHE A CG 1 ATOM 3227 C CD1 . PHE A 1 394 ? 162.483 36.996 -42.587 1.00 21.35 ? 402 PHE A CD1 1 ATOM 3228 C CD2 . PHE A 1 394 ? 163.617 34.954 -43.132 1.00 21.75 ? 402 PHE A CD2 1 ATOM 3229 C CE1 . PHE A 1 394 ? 161.781 36.932 -43.790 1.00 21.43 ? 402 PHE A CE1 1 ATOM 3230 C CE2 . PHE A 1 394 ? 162.921 34.879 -44.335 1.00 22.25 ? 402 PHE A CE2 1 ATOM 3231 C CZ . PHE A 1 394 ? 162.001 35.869 -44.665 1.00 22.00 ? 402 PHE A CZ 1 ATOM 3232 N N . SER A 1 395 ? 161.404 34.292 -40.491 1.00 25.57 ? 403 SER A N 1 ATOM 3233 C CA . SER A 1 395 ? 160.778 33.018 -40.788 1.00 26.25 ? 403 SER A CA 1 ATOM 3234 C C . SER A 1 395 ? 159.908 33.136 -42.019 1.00 26.95 ? 403 SER A C 1 ATOM 3235 O O . SER A 1 395 ? 159.353 34.200 -42.299 1.00 28.28 ? 403 SER A O 1 ATOM 3236 C CB . SER A 1 395 ? 159.938 32.557 -39.604 1.00 26.66 ? 403 SER A CB 1 ATOM 3237 O OG . SER A 1 395 ? 158.948 33.520 -39.304 1.00 29.92 ? 403 SER A OG 1 ATOM 3238 N N . TRP A 1 396 ? 159.801 32.030 -42.750 1.00 27.13 ? 404 TRP A N 1 ATOM 3239 C CA . TRP A 1 396 ? 158.998 31.960 -43.961 1.00 25.44 ? 404 TRP A CA 1 ATOM 3240 C C . TRP A 1 396 ? 157.901 30.914 -43.766 1.00 26.88 ? 404 TRP A C 1 ATOM 3241 O O . TRP A 1 396 ? 158.187 29.770 -43.394 1.00 27.24 ? 404 TRP A O 1 ATOM 3242 C CB . TRP A 1 396 ? 159.882 31.575 -45.140 1.00 24.09 ? 404 TRP A CB 1 ATOM 3243 C CG . TRP A 1 396 ? 159.148 31.477 -46.437 1.00 24.08 ? 404 TRP A CG 1 ATOM 3244 C CD1 . TRP A 1 396 ? 158.423 32.461 -47.046 1.00 23.31 ? 404 TRP A CD1 1 ATOM 3245 C CD2 . TRP A 1 396 ? 159.100 30.343 -47.312 1.00 23.28 ? 404 TRP A CD2 1 ATOM 3246 N NE1 . TRP A 1 396 ? 157.930 32.014 -48.248 1.00 22.90 ? 404 TRP A NE1 1 ATOM 3247 C CE2 . TRP A 1 396 ? 158.331 30.718 -48.438 1.00 23.04 ? 404 TRP A CE2 1 ATOM 3248 C CE3 . TRP A 1 396 ? 159.638 29.049 -47.258 1.00 23.33 ? 404 TRP A CE3 1 ATOM 3249 C CZ2 . TRP A 1 396 ? 158.085 29.844 -49.503 1.00 22.40 ? 404 TRP A CZ2 1 ATOM 3250 C CZ3 . TRP A 1 396 ? 159.395 28.174 -48.322 1.00 23.09 ? 404 TRP A CZ3 1 ATOM 3251 C CH2 . TRP A 1 396 ? 158.625 28.581 -49.428 1.00 24.23 ? 404 TRP A CH2 1 ATOM 3252 N N . ASN A 1 397 ? 156.652 31.311 -44.009 1.00 26.48 ? 405 ASN A N 1 ATOM 3253 C CA . ASN A 1 397 ? 155.506 30.418 -43.862 1.00 27.26 ? 405 ASN A CA 1 ATOM 3254 C C . ASN A 1 397 ? 154.818 30.160 -45.202 1.00 28.53 ? 405 ASN A C 1 ATOM 3255 O O . ASN A 1 397 ? 154.341 31.094 -45.858 1.00 29.02 ? 405 ASN A O 1 ATOM 3256 C CB . ASN A 1 397 ? 154.505 31.022 -42.871 1.00 27.95 ? 405 ASN A CB 1 ATOM 3257 C CG . ASN A 1 397 ? 153.181 30.272 -42.838 1.00 28.38 ? 405 ASN A CG 1 ATOM 3258 O OD1 . ASN A 1 397 ? 152.268 30.552 -43.623 1.00 28.00 ? 405 ASN A OD1 1 ATOM 3259 N ND2 . ASN A 1 397 ? 153.074 29.309 -41.930 1.00 27.51 ? 405 ASN A ND2 1 ATOM 3260 N N . ARG A 1 398 ? 154.766 28.890 -45.596 1.00 28.52 ? 406 ARG A N 1 ATOM 3261 C CA . ARG A 1 398 ? 154.145 28.483 -46.856 1.00 28.33 ? 406 ARG A CA 1 ATOM 3262 C C . ARG A 1 398 ? 152.633 28.373 -46.721 1.00 29.08 ? 406 ARG A C 1 ATOM 3263 O O . ARG A 1 398 ? 152.111 28.177 -45.626 1.00 30.75 ? 406 ARG A O 1 ATOM 3264 C CB . ARG A 1 398 ? 154.711 27.138 -47.308 1.00 27.61 ? 406 ARG A CB 1 ATOM 3265 C CG . ARG A 1 398 ? 156.227 27.069 -47.255 1.00 28.88 ? 406 ARG A CG 1 ATOM 3266 C CD . ARG A 1 398 ? 156.725 25.759 -47.823 1.00 30.85 ? 406 ARG A CD 1 ATOM 3267 N NE . ARG A 1 398 ? 156.014 24.615 -47.259 1.00 32.43 ? 406 ARG A NE 1 ATOM 3268 C CZ . ARG A 1 398 ? 156.161 23.361 -47.679 1.00 33.07 ? 406 ARG A CZ 1 ATOM 3269 N NH1 . ARG A 1 398 ? 156.999 23.084 -48.668 1.00 32.39 ? 406 ARG A NH1 1 ATOM 3270 N NH2 . ARG A 1 398 ? 155.459 22.384 -47.122 1.00 32.92 ? 406 ARG A NH2 1 ATOM 3271 N N . ASN A 1 399 ? 151.925 28.497 -47.835 1.00 29.40 ? 407 ASN A N 1 ATOM 3272 C CA . ASN A 1 399 ? 150.475 28.408 -47.802 1.00 29.71 ? 407 ASN A CA 1 ATOM 3273 C C . ASN A 1 399 ? 149.980 26.973 -47.600 1.00 30.24 ? 407 ASN A C 1 ATOM 3274 O O . ASN A 1 399 ? 148.893 26.773 -47.058 1.00 30.38 ? 407 ASN A O 1 ATOM 3275 C CB . ASN A 1 399 ? 149.884 29.033 -49.077 1.00 30.52 ? 407 ASN A CB 1 ATOM 3276 C CG . ASN A 1 399 ? 149.844 30.564 -49.012 1.00 31.20 ? 407 ASN A CG 1 ATOM 3277 O OD1 . ASN A 1 399 ? 150.439 31.178 -48.114 1.00 32.05 ? 407 ASN A OD1 1 ATOM 3278 N ND2 . ASN A 1 399 ? 149.145 31.182 -49.961 1.00 28.44 ? 407 ASN A ND2 1 ATOM 3279 N N . GLN A 1 400 ? 150.777 25.984 -48.012 1.00 31.28 ? 408 GLN A N 1 ATOM 3280 C CA . GLN A 1 400 ? 150.403 24.573 -47.839 1.00 33.05 ? 408 GLN A CA 1 ATOM 3281 C C . GLN A 1 400 ? 150.479 24.148 -46.375 1.00 34.23 ? 408 GLN A C 1 ATOM 3282 O O . GLN A 1 400 ? 149.693 23.313 -45.926 1.00 37.21 ? 408 GLN A O 1 ATOM 3283 C CB . GLN A 1 400 ? 151.323 23.612 -48.601 1.00 32.69 ? 408 GLN A CB 1 ATOM 3284 C CG . GLN A 1 400 ? 151.746 24.018 -49.986 1.00 37.07 ? 408 GLN A CG 1 ATOM 3285 C CD . GLN A 1 400 ? 153.048 24.794 -49.980 1.00 37.70 ? 408 GLN A CD 1 ATOM 3286 O OE1 . GLN A 1 400 ? 153.078 25.976 -49.631 1.00 38.00 ? 408 GLN A OE1 1 ATOM 3287 N NE2 . GLN A 1 400 ? 154.136 24.126 -50.356 1.00 36.12 ? 408 GLN A NE2 1 ATOM 3288 N N . ASP A 1 401 ? 151.441 24.693 -45.638 1.00 33.35 ? 409 ASP A N 1 ATOM 3289 C CA . ASP A 1 401 ? 151.603 24.329 -44.237 1.00 33.12 ? 409 ASP A CA 1 ATOM 3290 C C . ASP A 1 401 ? 150.599 25.034 -43.343 1.00 34.29 ? 409 ASP A C 1 ATOM 3291 O O . ASP A 1 401 ? 149.818 25.872 -43.801 1.00 34.57 ? 409 ASP A O 1 ATOM 3292 C CB . ASP A 1 401 ? 153.019 24.652 -43.760 1.00 32.05 ? 409 ASP A CB 1 ATOM 3293 C CG . ASP A 1 401 ? 154.077 24.065 -44.660 1.00 32.09 ? 409 ASP A CG 1 ATOM 3294 O OD1 . ASP A 1 401 ? 153.887 22.928 -45.152 1.00 31.83 ? 409 ASP A OD1 1 ATOM 3295 O OD2 . ASP A 1 401 ? 155.101 24.739 -44.872 1.00 32.05 ? 409 ASP A OD2 1 ATOM 3296 N N . GLY A 1 402 ? 150.618 24.670 -42.064 1.00 34.77 ? 410 GLY A N 1 ATOM 3297 C CA . GLY A 1 402 ? 149.722 25.283 -41.109 1.00 34.79 ? 410 GLY A CA 1 ATOM 3298 C C . GLY A 1 402 ? 150.188 26.699 -40.840 1.00 35.31 ? 410 GLY A C 1 ATOM 3299 O O . GLY A 1 402 ? 151.357 27.030 -41.066 1.00 35.40 ? 410 GLY A O 1 ATOM 3300 N N . VAL A 1 403 ? 149.282 27.533 -40.347 1.00 35.45 ? 411 VAL A N 1 ATOM 3301 C CA . VAL A 1 403 ? 149.598 28.924 -40.065 1.00 36.00 ? 411 VAL A CA 1 ATOM 3302 C C . VAL A 1 403 ? 150.786 29.132 -39.122 1.00 36.02 ? 411 VAL A C 1 ATOM 3303 O O . VAL A 1 403 ? 151.425 30.186 -39.158 1.00 36.61 ? 411 VAL A O 1 ATOM 3304 C CB . VAL A 1 403 ? 148.367 29.655 -39.485 1.00 36.01 ? 411 VAL A CB 1 ATOM 3305 C CG1 . VAL A 1 403 ? 147.200 29.547 -40.454 1.00 34.95 ? 411 VAL A CG1 1 ATOM 3306 C CG2 . VAL A 1 403 ? 147.997 29.065 -38.141 1.00 35.43 ? 411 VAL A CG2 1 ATOM 3307 N N . ALA A 1 404 ? 151.092 28.139 -38.289 1.00 36.11 ? 412 ALA A N 1 ATOM 3308 C CA . ALA A 1 404 ? 152.204 28.268 -37.342 1.00 35.87 ? 412 ALA A CA 1 ATOM 3309 C C . ALA A 1 404 ? 153.494 27.549 -37.751 1.00 35.90 ? 412 ALA A C 1 ATOM 3310 O O . ALA A 1 404 ? 154.493 27.593 -37.022 1.00 36.35 ? 412 ALA A O 1 ATOM 3311 C CB . ALA A 1 404 ? 151.763 27.794 -35.966 1.00 34.34 ? 412 ALA A CB 1 ATOM 3312 N N . VAL A 1 405 ? 153.479 26.900 -38.914 1.00 35.26 ? 413 VAL A N 1 ATOM 3313 C CA . VAL A 1 405 ? 154.651 26.172 -39.403 1.00 34.94 ? 413 VAL A CA 1 ATOM 3314 C C . VAL A 1 405 ? 155.647 27.088 -40.121 1.00 35.15 ? 413 VAL A C 1 ATOM 3315 O O . VAL A 1 405 ? 155.282 27.784 -41.067 1.00 36.14 ? 413 VAL A O 1 ATOM 3316 C CB . VAL A 1 405 ? 154.239 25.064 -40.397 1.00 33.95 ? 413 VAL A CB 1 ATOM 3317 C CG1 . VAL A 1 405 ? 155.430 24.183 -40.717 1.00 31.69 ? 413 VAL A CG1 1 ATOM 3318 C CG2 . VAL A 1 405 ? 153.105 24.245 -39.823 1.00 33.81 ? 413 VAL A CG2 1 ATOM 3319 N N . GLU A 1 406 ? 156.900 27.085 -39.680 1.00 34.04 ? 414 GLU A N 1 ATOM 3320 C CA . GLU A 1 406 ? 157.923 27.908 -40.314 1.00 33.41 ? 414 GLU A CA 1 ATOM 3321 C C . GLU A 1 406 ? 158.757 27.019 -41.230 1.00 32.23 ? 414 GLU A C 1 ATOM 3322 O O . GLU A 1 406 ? 159.652 26.319 -40.776 1.00 32.27 ? 414 GLU A O 1 ATOM 3323 C CB . GLU A 1 406 ? 158.823 28.548 -39.257 1.00 34.62 ? 414 GLU A CB 1 ATOM 3324 C CG . GLU A 1 406 ? 158.121 29.535 -38.328 1.00 39.25 ? 414 GLU A CG 1 ATOM 3325 C CD . GLU A 1 406 ? 159.034 30.021 -37.197 1.00 43.38 ? 414 GLU A CD 1 ATOM 3326 O OE1 . GLU A 1 406 ? 160.228 30.264 -37.462 1.00 46.19 ? 414 GLU A OE1 1 ATOM 3327 O OE2 . GLU A 1 406 ? 158.571 30.172 -36.044 1.00 45.87 ? 414 GLU A OE2 1 ATOM 3328 N N . ALA A 1 407 ? 158.455 27.046 -42.524 1.00 32.33 ? 415 ALA A N 1 ATOM 3329 C CA . ALA A 1 407 ? 159.171 26.231 -43.509 1.00 31.73 ? 415 ALA A CA 1 ATOM 3330 C C . ALA A 1 407 ? 160.647 26.592 -43.581 1.00 31.76 ? 415 ALA A C 1 ATOM 3331 O O . ALA A 1 407 ? 161.477 25.799 -44.026 1.00 32.24 ? 415 ALA A O 1 ATOM 3332 C CB . ALA A 1 407 ? 158.534 26.392 -44.884 1.00 31.85 ? 415 ALA A CB 1 ATOM 3333 N N . ASP A 1 408 ? 160.968 27.804 -43.153 1.00 31.64 ? 416 ASP A N 1 ATOM 3334 C CA . ASP A 1 408 ? 162.347 28.262 -43.148 1.00 31.93 ? 416 ASP A CA 1 ATOM 3335 C C . ASP A 1 408 ? 162.506 29.315 -42.069 1.00 33.15 ? 416 ASP A C 1 ATOM 3336 O O . ASP A 1 408 ? 161.782 30.306 -42.052 1.00 35.36 ? 416 ASP A O 1 ATOM 3337 C CB . ASP A 1 408 ? 162.733 28.855 -44.499 1.00 30.90 ? 416 ASP A CB 1 ATOM 3338 C CG . ASP A 1 408 ? 164.171 29.321 -44.527 1.00 30.39 ? 416 ASP A CG 1 ATOM 3339 O OD1 . ASP A 1 408 ? 165.010 28.609 -43.949 1.00 33.49 ? 416 ASP A OD1 1 ATOM 3340 O OD2 . ASP A 1 408 ? 164.474 30.379 -45.120 1.00 29.60 ? 416 ASP A OD2 1 ATOM 3341 N N . SER A 1 409 ? 163.433 29.087 -41.147 1.00 33.45 ? 417 SER A N 1 ATOM 3342 C CA . SER A 1 409 ? 163.664 30.045 -40.081 1.00 32.65 ? 417 SER A CA 1 ATOM 3343 C C . SER A 1 409 ? 165.158 30.295 -39.996 1.00 31.38 ? 417 SER A C 1 ATOM 3344 O O . SER A 1 409 ? 165.967 29.398 -40.237 1.00 31.28 ? 417 SER A O 1 ATOM 3345 C CB . SER A 1 409 ? 163.137 29.514 -38.750 1.00 33.57 ? 417 SER A CB 1 ATOM 3346 O OG . SER A 1 409 ? 164.027 28.559 -38.208 1.00 38.67 ? 417 SER A OG 1 ATOM 3347 N N . VAL A 1 410 ? 165.515 31.527 -39.666 1.00 29.82 ? 418 VAL A N 1 ATOM 3348 C CA . VAL A 1 410 ? 166.910 31.909 -39.572 1.00 28.62 ? 418 VAL A CA 1 ATOM 3349 C C . VAL A 1 410 ? 167.091 33.024 -38.564 1.00 27.34 ? 418 VAL A C 1 ATOM 3350 O O . VAL A 1 410 ? 166.272 33.933 -38.485 1.00 27.38 ? 418 VAL A O 1 ATOM 3351 C CB . VAL A 1 410 ? 167.436 32.439 -40.920 1.00 28.84 ? 418 VAL A CB 1 ATOM 3352 C CG1 . VAL A 1 410 ? 168.925 32.703 -40.823 1.00 29.57 ? 418 VAL A CG1 1 ATOM 3353 C CG2 . VAL A 1 410 ? 167.134 31.453 -42.021 1.00 30.11 ? 418 VAL A CG2 1 ATOM 3354 N N . TRP A 1 411 ? 168.163 32.952 -37.787 1.00 26.97 ? 419 TRP A N 1 ATOM 3355 C CA . TRP A 1 411 ? 168.449 34.009 -36.835 1.00 26.74 ? 419 TRP A CA 1 ATOM 3356 C C . TRP A 1 411 ? 169.432 34.953 -37.504 1.00 26.84 ? 419 TRP A C 1 ATOM 3357 O O . TRP A 1 411 ? 170.434 34.521 -38.083 1.00 27.63 ? 419 TRP A O 1 ATOM 3358 C CB . TRP A 1 411 ? 169.054 33.456 -35.548 1.00 27.34 ? 419 TRP A CB 1 ATOM 3359 C CG . TRP A 1 411 ? 168.019 32.949 -34.609 1.00 29.57 ? 419 TRP A CG 1 ATOM 3360 C CD1 . TRP A 1 411 ? 167.583 31.661 -34.479 1.00 30.60 ? 419 TRP A CD1 1 ATOM 3361 C CD2 . TRP A 1 411 ? 167.216 33.734 -33.724 1.00 30.20 ? 419 TRP A CD2 1 ATOM 3362 N NE1 . TRP A 1 411 ? 166.553 31.597 -33.571 1.00 31.80 ? 419 TRP A NE1 1 ATOM 3363 C CE2 . TRP A 1 411 ? 166.307 32.858 -33.091 1.00 29.80 ? 419 TRP A CE2 1 ATOM 3364 C CE3 . TRP A 1 411 ? 167.171 35.101 -33.406 1.00 30.37 ? 419 TRP A CE3 1 ATOM 3365 C CZ2 . TRP A 1 411 ? 165.363 33.296 -32.160 1.00 29.88 ? 419 TRP A CZ2 1 ATOM 3366 C CZ3 . TRP A 1 411 ? 166.231 35.541 -32.480 1.00 30.92 ? 419 TRP A CZ3 1 ATOM 3367 C CH2 . TRP A 1 411 ? 165.339 34.639 -31.868 1.00 31.92 ? 419 TRP A CH2 1 ATOM 3368 N N . PHE A 1 412 ? 169.119 36.242 -37.455 1.00 26.57 ? 420 PHE A N 1 ATOM 3369 C CA . PHE A 1 412 ? 169.974 37.263 -38.036 1.00 26.22 ? 420 PHE A CA 1 ATOM 3370 C C . PHE A 1 412 ? 170.775 37.911 -36.917 1.00 25.88 ? 420 PHE A C 1 ATOM 3371 O O . PHE A 1 412 ? 170.203 38.352 -35.918 1.00 25.12 ? 420 PHE A O 1 ATOM 3372 C CB . PHE A 1 412 ? 169.147 38.367 -38.701 1.00 27.14 ? 420 PHE A CB 1 ATOM 3373 C CG . PHE A 1 412 ? 168.754 38.085 -40.118 1.00 28.66 ? 420 PHE A CG 1 ATOM 3374 C CD1 . PHE A 1 412 ? 167.829 37.094 -40.420 1.00 29.33 ? 420 PHE A CD1 1 ATOM 3375 C CD2 . PHE A 1 412 ? 169.269 38.858 -41.154 1.00 29.44 ? 420 PHE A CD2 1 ATOM 3376 C CE1 . PHE A 1 412 ? 167.414 36.876 -41.730 1.00 28.91 ? 420 PHE A CE1 1 ATOM 3377 C CE2 . PHE A 1 412 ? 168.859 38.645 -42.471 1.00 30.46 ? 420 PHE A CE2 1 ATOM 3378 C CZ . PHE A 1 412 ? 167.928 37.652 -42.755 1.00 29.83 ? 420 PHE A CZ 1 ATOM 3379 N N . PHE A 1 413 ? 172.091 37.967 -37.072 1.00 25.77 ? 421 PHE A N 1 ATOM 3380 C CA . PHE A 1 413 ? 172.915 38.623 -36.070 1.00 25.22 ? 421 PHE A CA 1 ATOM 3381 C C . PHE A 1 413 ? 173.262 39.987 -36.653 1.00 25.66 ? 421 PHE A C 1 ATOM 3382 O O . PHE A 1 413 ? 173.788 40.083 -37.767 1.00 25.54 ? 421 PHE A O 1 ATOM 3383 C CB . PHE A 1 413 ? 174.172 37.805 -35.777 1.00 24.68 ? 421 PHE A CB 1 ATOM 3384 C CG . PHE A 1 413 ? 173.883 36.458 -35.179 1.00 26.79 ? 421 PHE A CG 1 ATOM 3385 C CD1 . PHE A 1 413 ? 172.790 36.280 -34.336 1.00 27.38 ? 421 PHE A CD1 1 ATOM 3386 C CD2 . PHE A 1 413 ? 174.701 35.364 -35.448 1.00 27.84 ? 421 PHE A CD2 1 ATOM 3387 C CE1 . PHE A 1 413 ? 172.515 35.030 -33.770 1.00 28.06 ? 421 PHE A CE1 1 ATOM 3388 C CE2 . PHE A 1 413 ? 174.435 34.112 -34.886 1.00 27.08 ? 421 PHE A CE2 1 ATOM 3389 C CZ . PHE A 1 413 ? 173.339 33.948 -34.047 1.00 27.37 ? 421 PHE A CZ 1 ATOM 3390 N N . ASN A 1 414 ? 172.944 41.038 -35.903 1.00 24.40 ? 422 ASN A N 1 ATOM 3391 C CA . ASN A 1 414 ? 173.181 42.402 -36.350 1.00 24.23 ? 422 ASN A CA 1 ATOM 3392 C C . ASN A 1 414 ? 174.610 42.629 -36.839 1.00 24.00 ? 422 ASN A C 1 ATOM 3393 O O . ASN A 1 414 ? 175.568 42.271 -36.160 1.00 26.01 ? 422 ASN A O 1 ATOM 3394 C CB . ASN A 1 414 ? 172.821 43.374 -35.219 1.00 23.18 ? 422 ASN A CB 1 ATOM 3395 C CG . ASN A 1 414 ? 172.792 44.809 -35.679 1.00 23.24 ? 422 ASN A CG 1 ATOM 3396 O OD1 . ASN A 1 414 ? 173.790 45.524 -35.574 1.00 24.43 ? 422 ASN A OD1 1 ATOM 3397 N ND2 . ASN A 1 414 ? 171.646 45.241 -36.206 1.00 21.42 ? 422 ASN A ND2 1 ATOM 3398 N N . ARG A 1 415 ? 174.750 43.216 -38.025 1.00 23.75 ? 423 ARG A N 1 ATOM 3399 C CA . ARG A 1 415 ? 176.069 43.474 -38.605 1.00 23.61 ? 423 ARG A CA 1 ATOM 3400 C C . ARG A 1 415 ? 176.851 44.542 -37.855 1.00 23.57 ? 423 ARG A C 1 ATOM 3401 O O . ARG A 1 415 ? 178.062 44.656 -38.010 1.00 22.36 ? 423 ARG A O 1 ATOM 3402 C CB . ARG A 1 415 ? 175.944 43.908 -40.074 1.00 22.89 ? 423 ARG A CB 1 ATOM 3403 C CG . ARG A 1 415 ? 175.559 42.810 -41.055 1.00 22.01 ? 423 ARG A CG 1 ATOM 3404 C CD . ARG A 1 415 ? 176.502 41.618 -40.981 1.00 21.83 ? 423 ARG A CD 1 ATOM 3405 N NE . ARG A 1 415 ? 176.086 40.678 -39.945 1.00 24.37 ? 423 ARG A NE 1 ATOM 3406 C CZ . ARG A 1 415 ? 176.713 39.538 -39.665 1.00 26.81 ? 423 ARG A CZ 1 ATOM 3407 N NH1 . ARG A 1 415 ? 177.798 39.188 -40.347 1.00 26.65 ? 423 ARG A NH1 1 ATOM 3408 N NH2 . ARG A 1 415 ? 176.253 38.744 -38.702 1.00 25.73 ? 423 ARG A NH2 1 ATOM 3409 N N . HIS A 1 416 ? 176.161 45.330 -37.045 1.00 24.33 ? 424 HIS A N 1 ATOM 3410 C CA . HIS A 1 416 ? 176.832 46.387 -36.312 1.00 24.77 ? 424 HIS A CA 1 ATOM 3411 C C . HIS A 1 416 ? 177.145 46.008 -34.873 1.00 25.71 ? 424 HIS A C 1 ATOM 3412 O O . HIS A 1 416 ? 178.254 46.241 -34.398 1.00 26.32 ? 424 HIS A O 1 ATOM 3413 C CB . HIS A 1 416 ? 175.983 47.657 -36.320 1.00 25.09 ? 424 HIS A CB 1 ATOM 3414 C CG . HIS A 1 416 ? 176.647 48.821 -35.653 1.00 27.35 ? 424 HIS A CG 1 ATOM 3415 N ND1 . HIS A 1 416 ? 177.638 49.560 -36.263 1.00 27.62 ? 424 HIS A ND1 1 ATOM 3416 C CD2 . HIS A 1 416 ? 176.506 49.334 -34.407 1.00 27.55 ? 424 HIS A CD2 1 ATOM 3417 C CE1 . HIS A 1 416 ? 178.081 50.477 -35.422 1.00 28.01 ? 424 HIS A CE1 1 ATOM 3418 N NE2 . HIS A 1 416 ? 177.411 50.362 -34.288 1.00 29.47 ? 424 HIS A NE2 1 ATOM 3419 N N . TRP A 1 417 ? 176.173 45.425 -34.180 1.00 25.99 ? 425 TRP A N 1 ATOM 3420 C CA . TRP A 1 417 ? 176.374 45.056 -32.782 1.00 27.52 ? 425 TRP A CA 1 ATOM 3421 C C . TRP A 1 417 ? 176.806 43.608 -32.502 1.00 29.07 ? 425 TRP A C 1 ATOM 3422 O O . TRP A 1 417 ? 177.437 43.329 -31.475 1.00 30.63 ? 425 TRP A O 1 ATOM 3423 C CB . TRP A 1 417 ? 175.104 45.354 -31.978 1.00 25.75 ? 425 TRP A CB 1 ATOM 3424 C CG . TRP A 1 417 ? 174.733 46.792 -31.939 1.00 25.34 ? 425 TRP A CG 1 ATOM 3425 C CD1 . TRP A 1 417 ? 173.939 47.453 -32.819 1.00 25.70 ? 425 TRP A CD1 1 ATOM 3426 C CD2 . TRP A 1 417 ? 175.164 47.763 -30.979 1.00 26.59 ? 425 TRP A CD2 1 ATOM 3427 N NE1 . TRP A 1 417 ? 173.842 48.778 -32.473 1.00 24.01 ? 425 TRP A NE1 1 ATOM 3428 C CE2 . TRP A 1 417 ? 174.585 48.996 -31.346 1.00 25.19 ? 425 TRP A CE2 1 ATOM 3429 C CE3 . TRP A 1 417 ? 175.986 47.713 -29.840 1.00 26.49 ? 425 TRP A CE3 1 ATOM 3430 C CZ2 . TRP A 1 417 ? 174.799 50.171 -30.620 1.00 26.37 ? 425 TRP A CZ2 1 ATOM 3431 C CZ3 . TRP A 1 417 ? 176.200 48.880 -29.118 1.00 23.52 ? 425 TRP A CZ3 1 ATOM 3432 C CH2 . TRP A 1 417 ? 175.609 50.091 -29.510 1.00 25.46 ? 425 TRP A CH2 1 ATOM 3433 N N . TYR A 1 418 ? 176.477 42.691 -33.405 1.00 28.61 ? 426 TYR A N 1 ATOM 3434 C CA . TYR A 1 418 ? 176.805 41.286 -33.205 1.00 27.84 ? 426 TYR A CA 1 ATOM 3435 C C . TYR A 1 418 ? 177.332 40.680 -34.507 1.00 28.09 ? 426 TYR A C 1 ATOM 3436 O O . TYR A 1 418 ? 176.738 39.755 -35.060 1.00 27.82 ? 426 TYR A O 1 ATOM 3437 C CB . TYR A 1 418 ? 175.539 40.561 -32.742 1.00 28.32 ? 426 TYR A CB 1 ATOM 3438 C CG . TYR A 1 418 ? 175.802 39.357 -31.880 1.00 30.09 ? 426 TYR A CG 1 ATOM 3439 C CD1 . TYR A 1 418 ? 176.472 39.486 -30.667 1.00 30.93 ? 426 TYR A CD1 1 ATOM 3440 C CD2 . TYR A 1 418 ? 175.407 38.083 -32.286 1.00 30.53 ? 426 TYR A CD2 1 ATOM 3441 C CE1 . TYR A 1 418 ? 176.749 38.380 -29.879 1.00 31.83 ? 426 TYR A CE1 1 ATOM 3442 C CE2 . TYR A 1 418 ? 175.680 36.967 -31.507 1.00 31.67 ? 426 TYR A CE2 1 ATOM 3443 C CZ . TYR A 1 418 ? 176.354 37.124 -30.307 1.00 33.09 ? 426 TYR A CZ 1 ATOM 3444 O OH . TYR A 1 418 ? 176.655 36.016 -29.544 1.00 36.95 ? 426 TYR A OH 1 ATOM 3445 N N . PRO A 1 419 ? 178.473 41.188 -34.999 1.00 29.22 ? 427 PRO A N 1 ATOM 3446 C CA . PRO A 1 419 ? 179.133 40.756 -36.239 1.00 30.21 ? 427 PRO A CA 1 ATOM 3447 C C . PRO A 1 419 ? 179.637 39.313 -36.296 1.00 32.46 ? 427 PRO A C 1 ATOM 3448 O O . PRO A 1 419 ? 180.804 39.073 -36.619 1.00 33.82 ? 427 PRO A O 1 ATOM 3449 C CB . PRO A 1 419 ? 180.290 41.746 -36.384 1.00 29.41 ? 427 PRO A CB 1 ATOM 3450 C CG . PRO A 1 419 ? 179.903 42.904 -35.520 1.00 31.00 ? 427 PRO A CG 1 ATOM 3451 C CD . PRO A 1 419 ? 179.264 42.242 -34.345 1.00 29.45 ? 427 PRO A CD 1 ATOM 3452 N N . VAL A 1 420 ? 178.777 38.348 -36.001 1.00 33.18 ? 428 VAL A N 1 ATOM 3453 C CA . VAL A 1 420 ? 179.213 36.961 -36.048 1.00 35.25 ? 428 VAL A CA 1 ATOM 3454 C C . VAL A 1 420 ? 178.549 36.216 -37.189 1.00 36.99 ? 428 VAL A C 1 ATOM 3455 O O . VAL A 1 420 ? 177.444 36.563 -37.614 1.00 37.37 ? 428 VAL A O 1 ATOM 3456 C CB . VAL A 1 420 ? 178.921 36.227 -34.730 1.00 35.11 ? 428 VAL A CB 1 ATOM 3457 C CG1 . VAL A 1 420 ? 179.786 36.795 -33.625 1.00 36.35 ? 428 VAL A CG1 1 ATOM 3458 C CG2 . VAL A 1 420 ? 177.466 36.372 -34.368 1.00 36.55 ? 428 VAL A CG2 1 ATOM 3459 N N . ASP A 1 421 ? 179.236 35.192 -37.682 1.00 38.23 ? 429 ASP A N 1 ATOM 3460 C CA . ASP A 1 421 ? 178.736 34.388 -38.783 1.00 38.66 ? 429 ASP A CA 1 ATOM 3461 C C . ASP A 1 421 ? 177.379 33.780 -38.458 1.00 38.05 ? 429 ASP A C 1 ATOM 3462 O O . ASP A 1 421 ? 177.280 32.899 -37.609 1.00 38.65 ? 429 ASP A O 1 ATOM 3463 C CB . ASP A 1 421 ? 179.727 33.274 -39.105 1.00 40.23 ? 429 ASP A CB 1 ATOM 3464 C CG . ASP A 1 421 ? 179.301 32.450 -40.298 1.00 43.49 ? 429 ASP A CG 1 ATOM 3465 O OD1 . ASP A 1 421 ? 179.977 31.442 -40.602 1.00 45.78 ? 429 ASP A OD1 1 ATOM 3466 O OD2 . ASP A 1 421 ? 178.291 32.813 -40.934 1.00 44.67 ? 429 ASP A OD2 1 ATOM 3467 N N . ASP A 1 422 ? 176.334 34.257 -39.127 1.00 37.06 ? 430 ASP A N 1 ATOM 3468 C CA . ASP A 1 422 ? 174.993 33.734 -38.903 1.00 37.39 ? 430 ASP A CA 1 ATOM 3469 C C . ASP A 1 422 ? 174.511 32.855 -40.061 1.00 39.75 ? 430 ASP A C 1 ATOM 3470 O O . ASP A 1 422 ? 173.321 32.828 -40.378 1.00 40.75 ? 430 ASP A O 1 ATOM 3471 C CB . ASP A 1 422 ? 173.999 34.882 -38.643 1.00 35.44 ? 430 ASP A CB 1 ATOM 3472 C CG . ASP A 1 422 ? 174.018 35.956 -39.726 1.00 33.80 ? 430 ASP A CG 1 ATOM 3473 O OD1 . ASP A 1 422 ? 173.209 36.903 -39.618 1.00 30.98 ? 430 ASP A OD1 1 ATOM 3474 O OD2 . ASP A 1 422 ? 174.832 35.867 -40.672 1.00 33.06 ? 430 ASP A OD2 1 ATOM 3475 N N . SER A 1 423 ? 175.445 32.128 -40.674 1.00 41.28 ? 431 SER A N 1 ATOM 3476 C CA . SER A 1 423 ? 175.145 31.228 -41.790 1.00 42.91 ? 431 SER A CA 1 ATOM 3477 C C . SER A 1 423 ? 174.348 30.015 -41.314 1.00 43.57 ? 431 SER A C 1 ATOM 3478 O O . SER A 1 423 ? 174.418 29.649 -40.141 1.00 43.34 ? 431 SER A O 1 ATOM 3479 C CB . SER A 1 423 ? 176.442 30.727 -42.437 1.00 43.08 ? 431 SER A CB 1 ATOM 3480 O OG . SER A 1 423 ? 177.240 31.795 -42.916 1.00 45.88 ? 431 SER A OG 1 ATOM 3481 N N . THR A 1 424 ? 173.606 29.387 -42.227 1.00 44.92 ? 432 THR A N 1 ATOM 3482 C CA . THR A 1 424 ? 172.815 28.201 -41.887 1.00 45.54 ? 432 THR A CA 1 ATOM 3483 C C . THR A 1 424 ? 173.399 26.935 -42.516 1.00 46.21 ? 432 THR A C 1 ATOM 3484 O O . THR A 1 424 ? 174.467 26.964 -43.132 1.00 47.64 ? 432 THR A O 1 ATOM 3485 C CB . THR A 1 424 ? 171.354 28.335 -42.355 1.00 44.83 ? 432 THR A CB 1 ATOM 3486 O OG1 . THR A 1 424 ? 171.296 28.215 -43.782 1.00 43.32 ? 432 THR A OG1 1 ATOM 3487 C CG2 . THR A 1 424 ? 170.783 29.681 -41.918 1.00 44.74 ? 432 THR A CG2 1 ATOM 3488 N N . ARG B 1 1 ? 188.745 78.154 -65.576 1.00 39.37 ? 9 ARG B N 1 ATOM 3489 C CA . ARG B 1 1 ? 189.194 79.180 -66.516 1.00 39.67 ? 9 ARG B CA 1 ATOM 3490 C C . ARG B 1 1 ? 188.255 79.391 -67.714 1.00 36.95 ? 9 ARG B C 1 ATOM 3491 O O . ARG B 1 1 ? 188.652 79.231 -68.872 1.00 34.14 ? 9 ARG B O 1 ATOM 3492 C CB . ARG B 1 1 ? 190.615 78.862 -67.011 1.00 42.60 ? 9 ARG B CB 1 ATOM 3493 C CG . ARG B 1 1 ? 190.775 77.539 -67.765 1.00 46.30 ? 9 ARG B CG 1 ATOM 3494 C CD . ARG B 1 1 ? 192.255 77.209 -68.034 1.00 50.38 ? 9 ARG B CD 1 ATOM 3495 N NE . ARG B 1 1 ? 192.614 77.247 -69.456 1.00 54.68 ? 9 ARG B NE 1 ATOM 3496 C CZ . ARG B 1 1 ? 192.781 78.361 -70.172 1.00 57.00 ? 9 ARG B CZ 1 ATOM 3497 N NH1 . ARG B 1 1 ? 192.629 79.559 -69.611 1.00 57.30 ? 9 ARG B NH1 1 ATOM 3498 N NH2 . ARG B 1 1 ? 193.098 78.280 -71.461 1.00 56.76 ? 9 ARG B NH2 1 ATOM 3499 N N . ASP B 1 2 ? 187.006 79.749 -67.425 1.00 35.93 ? 10 ASP B N 1 ATOM 3500 C CA . ASP B 1 2 ? 186.024 80.009 -68.476 1.00 35.83 ? 10 ASP B CA 1 ATOM 3501 C C . ASP B 1 2 ? 186.308 81.393 -69.043 1.00 35.00 ? 10 ASP B C 1 ATOM 3502 O O . ASP B 1 2 ? 187.074 82.161 -68.457 1.00 35.20 ? 10 ASP B O 1 ATOM 3503 C CB . ASP B 1 2 ? 184.587 79.982 -67.921 1.00 35.75 ? 10 ASP B CB 1 ATOM 3504 C CG . ASP B 1 2 ? 184.079 78.569 -67.649 1.00 36.68 ? 10 ASP B CG 1 ATOM 3505 O OD1 . ASP B 1 2 ? 184.247 77.680 -68.513 1.00 38.62 ? 10 ASP B OD1 1 ATOM 3506 O OD2 . ASP B 1 2 ? 183.497 78.349 -66.572 1.00 37.50 ? 10 ASP B OD2 1 ATOM 3507 N N . MET B 1 3 ? 185.708 81.709 -70.185 1.00 33.67 ? 11 MET B N 1 ATOM 3508 C CA . MET B 1 3 ? 185.909 83.019 -70.788 1.00 33.15 ? 11 MET B CA 1 ATOM 3509 C C . MET B 1 3 ? 185.053 84.037 -70.037 1.00 34.33 ? 11 MET B C 1 ATOM 3510 O O . MET B 1 3 ? 183.891 83.772 -69.722 1.00 35.05 ? 11 MET B O 1 ATOM 3511 C CB . MET B 1 3 ? 185.516 83.000 -72.265 1.00 31.00 ? 11 MET B CB 1 ATOM 3512 C CG . MET B 1 3 ? 186.292 81.998 -73.101 1.00 29.62 ? 11 MET B CG 1 ATOM 3513 S SD . MET B 1 3 ? 185.778 82.002 -74.826 1.00 27.93 ? 11 MET B SD 1 ATOM 3514 C CE . MET B 1 3 ? 184.350 80.909 -74.746 1.00 28.36 ? 11 MET B CE 1 ATOM 3515 N N . PRO B 1 4 ? 185.625 85.212 -69.720 1.00 35.80 ? 12 PRO B N 1 ATOM 3516 C CA . PRO B 1 4 ? 184.903 86.271 -69.000 1.00 35.54 ? 12 PRO B CA 1 ATOM 3517 C C . PRO B 1 4 ? 183.670 86.787 -69.748 1.00 34.44 ? 12 PRO B C 1 ATOM 3518 O O . PRO B 1 4 ? 183.604 86.732 -70.979 1.00 33.96 ? 12 PRO B O 1 ATOM 3519 C CB . PRO B 1 4 ? 185.975 87.347 -68.801 1.00 36.57 ? 12 PRO B CB 1 ATOM 3520 C CG . PRO B 1 4 ? 186.927 87.113 -69.954 1.00 36.69 ? 12 PRO B CG 1 ATOM 3521 C CD . PRO B 1 4 ? 187.019 85.611 -69.991 1.00 35.80 ? 12 PRO B CD 1 ATOM 3522 N N . LEU B 1 5 ? 182.698 87.290 -68.996 1.00 33.99 ? 13 LEU B N 1 ATOM 3523 C CA . LEU B 1 5 ? 181.465 87.790 -69.580 1.00 34.22 ? 13 LEU B CA 1 ATOM 3524 C C . LEU B 1 5 ? 181.656 88.871 -70.634 1.00 35.61 ? 13 LEU B C 1 ATOM 3525 O O . LEU B 1 5 ? 180.795 89.055 -71.493 1.00 35.31 ? 13 LEU B O 1 ATOM 3526 C CB . LEU B 1 5 ? 180.545 88.310 -68.482 1.00 34.23 ? 13 LEU B CB 1 ATOM 3527 C CG . LEU B 1 5 ? 180.160 87.311 -67.385 1.00 35.09 ? 13 LEU B CG 1 ATOM 3528 C CD1 . LEU B 1 5 ? 179.121 87.945 -66.475 1.00 35.92 ? 13 LEU B CD1 1 ATOM 3529 C CD2 . LEU B 1 5 ? 179.603 86.037 -68.001 1.00 34.06 ? 13 LEU B CD2 1 ATOM 3530 N N . ASP B 1 6 ? 182.775 89.588 -70.581 1.00 37.23 ? 14 ASP B N 1 ATOM 3531 C CA . ASP B 1 6 ? 183.019 90.640 -71.564 1.00 38.36 ? 14 ASP B CA 1 ATOM 3532 C C . ASP B 1 6 ? 183.725 90.148 -72.824 1.00 37.74 ? 14 ASP B C 1 ATOM 3533 O O . ASP B 1 6 ? 184.077 90.945 -73.693 1.00 37.15 ? 14 ASP B O 1 ATOM 3534 C CB . ASP B 1 6 ? 183.809 91.797 -70.932 1.00 42.00 ? 14 ASP B CB 1 ATOM 3535 C CG . ASP B 1 6 ? 185.055 91.333 -70.184 1.00 46.71 ? 14 ASP B CG 1 ATOM 3536 O OD1 . ASP B 1 6 ? 186.052 90.957 -70.842 1.00 47.98 ? 14 ASP B OD1 1 ATOM 3537 O OD2 . ASP B 1 6 ? 185.028 91.344 -68.929 1.00 49.31 ? 14 ASP B OD2 1 ATOM 3538 N N . SER B 1 7 ? 183.917 88.836 -72.933 1.00 37.49 ? 15 SER B N 1 ATOM 3539 C CA . SER B 1 7 ? 184.582 88.265 -74.100 1.00 36.74 ? 15 SER B CA 1 ATOM 3540 C C . SER B 1 7 ? 183.820 88.565 -75.380 1.00 36.53 ? 15 SER B C 1 ATOM 3541 O O . SER B 1 7 ? 182.591 88.581 -75.408 1.00 36.21 ? 15 SER B O 1 ATOM 3542 C CB . SER B 1 7 ? 184.748 86.760 -73.933 1.00 37.04 ? 15 SER B CB 1 ATOM 3543 O OG . SER B 1 7 ? 185.563 86.470 -72.814 1.00 39.32 ? 15 SER B OG 1 ATOM 3544 N N . ASP B 1 8 ? 184.572 88.798 -76.446 1.00 36.76 ? 16 ASP B N 1 ATOM 3545 C CA . ASP B 1 8 ? 184.002 89.133 -77.741 1.00 36.66 ? 16 ASP B CA 1 ATOM 3546 C C . ASP B 1 8 ? 182.952 88.146 -78.228 1.00 35.83 ? 16 ASP B C 1 ATOM 3547 O O . ASP B 1 8 ? 181.961 88.536 -78.844 1.00 36.02 ? 16 ASP B O 1 ATOM 3548 C CB . ASP B 1 8 ? 185.126 89.266 -78.783 1.00 38.44 ? 16 ASP B CB 1 ATOM 3549 C CG . ASP B 1 8 ? 185.830 87.943 -79.081 1.00 40.42 ? 16 ASP B CG 1 ATOM 3550 O OD1 . ASP B 1 8 ? 186.030 87.127 -78.155 1.00 42.06 ? 16 ASP B OD1 1 ATOM 3551 O OD2 . ASP B 1 8 ? 186.200 87.727 -80.254 1.00 41.95 ? 16 ASP B OD2 1 ATOM 3552 N N . VAL B 1 9 ? 183.153 86.869 -77.938 1.00 34.67 ? 17 VAL B N 1 ATOM 3553 C CA . VAL B 1 9 ? 182.221 85.852 -78.392 1.00 33.20 ? 17 VAL B CA 1 ATOM 3554 C C . VAL B 1 9 ? 180.881 85.842 -77.641 1.00 32.23 ? 17 VAL B C 1 ATOM 3555 O O . VAL B 1 9 ? 179.926 85.205 -78.080 1.00 31.94 ? 17 VAL B O 1 ATOM 3556 C CB . VAL B 1 9 ? 182.889 84.458 -78.338 1.00 33.46 ? 17 VAL B CB 1 ATOM 3557 C CG1 . VAL B 1 9 ? 183.035 83.994 -76.901 1.00 32.88 ? 17 VAL B CG1 1 ATOM 3558 C CG2 . VAL B 1 9 ? 182.096 83.475 -79.183 1.00 35.90 ? 17 VAL B CG2 1 ATOM 3559 N N . PHE B 1 10 ? 180.798 86.554 -76.521 1.00 31.61 ? 18 PHE B N 1 ATOM 3560 C CA . PHE B 1 10 ? 179.550 86.620 -75.756 1.00 30.52 ? 18 PHE B CA 1 ATOM 3561 C C . PHE B 1 10 ? 178.798 87.916 -76.065 1.00 32.14 ? 18 PHE B C 1 ATOM 3562 O O . PHE B 1 10 ? 177.706 88.166 -75.545 1.00 31.52 ? 18 PHE B O 1 ATOM 3563 C CB . PHE B 1 10 ? 179.828 86.546 -74.252 1.00 28.18 ? 18 PHE B CB 1 ATOM 3564 C CG . PHE B 1 10 ? 180.372 85.222 -73.792 1.00 25.44 ? 18 PHE B CG 1 ATOM 3565 C CD1 . PHE B 1 10 ? 179.974 84.034 -74.408 1.00 23.85 ? 18 PHE B CD1 1 ATOM 3566 C CD2 . PHE B 1 10 ? 181.242 85.159 -72.705 1.00 24.03 ? 18 PHE B CD2 1 ATOM 3567 C CE1 . PHE B 1 10 ? 180.435 82.801 -73.946 1.00 24.31 ? 18 PHE B CE1 1 ATOM 3568 C CE2 . PHE B 1 10 ? 181.712 83.933 -72.228 1.00 24.82 ? 18 PHE B CE2 1 ATOM 3569 C CZ . PHE B 1 10 ? 181.307 82.750 -72.849 1.00 24.44 ? 18 PHE B CZ 1 ATOM 3570 N N . ARG B 1 11 ? 179.406 88.736 -76.915 1.00 34.10 ? 19 ARG B N 1 ATOM 3571 C CA . ARG B 1 11 ? 178.842 90.013 -77.340 1.00 37.00 ? 19 ARG B CA 1 ATOM 3572 C C . ARG B 1 11 ? 177.372 89.836 -77.707 1.00 35.48 ? 19 ARG B C 1 ATOM 3573 O O . ARG B 1 11 ? 176.991 88.844 -78.324 1.00 36.31 ? 19 ARG B O 1 ATOM 3574 C CB . ARG B 1 11 ? 179.607 90.527 -78.567 1.00 42.73 ? 19 ARG B CB 1 ATOM 3575 C CG . ARG B 1 11 ? 179.592 92.034 -78.747 1.00 50.23 ? 19 ARG B CG 1 ATOM 3576 C CD . ARG B 1 11 ? 180.564 92.719 -77.781 1.00 55.94 ? 19 ARG B CD 1 ATOM 3577 N NE . ARG B 1 11 ? 181.969 92.480 -78.123 1.00 60.15 ? 19 ARG B NE 1 ATOM 3578 C CZ . ARG B 1 11 ? 182.510 92.737 -79.316 1.00 61.82 ? 19 ARG B CZ 1 ATOM 3579 N NH1 . ARG B 1 11 ? 181.766 93.239 -80.298 1.00 61.72 ? 19 ARG B NH1 1 ATOM 3580 N NH2 . ARG B 1 11 ? 183.803 92.505 -79.526 1.00 61.33 ? 19 ARG B NH2 1 ATOM 3581 N N . VAL B 1 12 ? 176.543 90.801 -77.342 1.00 33.94 ? 20 VAL B N 1 ATOM 3582 C CA . VAL B 1 12 ? 175.126 90.703 -77.659 1.00 33.42 ? 20 VAL B CA 1 ATOM 3583 C C . VAL B 1 12 ? 174.811 91.494 -78.922 1.00 32.86 ? 20 VAL B C 1 ATOM 3584 O O . VAL B 1 12 ? 175.149 92.673 -79.027 1.00 33.95 ? 20 VAL B O 1 ATOM 3585 C CB . VAL B 1 12 ? 174.258 91.216 -76.481 1.00 33.18 ? 20 VAL B CB 1 ATOM 3586 C CG1 . VAL B 1 12 ? 174.774 92.562 -76.002 1.00 36.06 ? 20 VAL B CG1 1 ATOM 3587 C CG2 . VAL B 1 12 ? 172.800 91.319 -76.905 1.00 31.84 ? 20 VAL B CG2 1 ATOM 3588 N N . PRO B 1 13 ? 174.172 90.850 -79.910 1.00 32.13 ? 21 PRO B N 1 ATOM 3589 C CA . PRO B 1 13 ? 173.829 91.533 -81.161 1.00 31.76 ? 21 PRO B CA 1 ATOM 3590 C C . PRO B 1 13 ? 173.053 92.826 -80.913 1.00 32.83 ? 21 PRO B C 1 ATOM 3591 O O . PRO B 1 13 ? 172.124 92.860 -80.107 1.00 33.36 ? 21 PRO B O 1 ATOM 3592 C CB . PRO B 1 13 ? 173.025 90.480 -81.924 1.00 31.41 ? 21 PRO B CB 1 ATOM 3593 C CG . PRO B 1 13 ? 172.464 89.623 -80.848 1.00 31.82 ? 21 PRO B CG 1 ATOM 3594 C CD . PRO B 1 13 ? 173.605 89.495 -79.882 1.00 31.45 ? 21 PRO B CD 1 ATOM 3595 N N . PRO B 1 14 ? 173.429 93.911 -81.617 1.00 33.97 ? 22 PRO B N 1 ATOM 3596 C CA . PRO B 1 14 ? 172.821 95.243 -81.513 1.00 32.50 ? 22 PRO B CA 1 ATOM 3597 C C . PRO B 1 14 ? 171.407 95.322 -82.057 1.00 31.67 ? 22 PRO B C 1 ATOM 3598 O O . PRO B 1 14 ? 170.988 94.483 -82.860 1.00 31.00 ? 22 PRO B O 1 ATOM 3599 C CB . PRO B 1 14 ? 173.778 96.107 -82.316 1.00 32.76 ? 22 PRO B CB 1 ATOM 3600 C CG . PRO B 1 14 ? 174.096 95.191 -83.463 1.00 33.04 ? 22 PRO B CG 1 ATOM 3601 C CD . PRO B 1 14 ? 174.382 93.875 -82.745 1.00 33.45 ? 22 PRO B CD 1 ATOM 3602 N N . GLY B 1 15 ? 170.689 96.357 -81.634 1.00 30.85 ? 23 GLY B N 1 ATOM 3603 C CA . GLY B 1 15 ? 169.322 96.543 -82.082 1.00 30.81 ? 23 GLY B CA 1 ATOM 3604 C C . GLY B 1 15 ? 168.349 96.255 -80.958 1.00 30.77 ? 23 GLY B C 1 ATOM 3605 O O . GLY B 1 15 ? 168.668 95.493 -80.040 1.00 31.27 ? 23 GLY B O 1 ATOM 3606 N N . TYR B 1 16 ? 167.165 96.859 -81.021 1.00 29.88 ? 24 TYR B N 1 ATOM 3607 C CA . TYR B 1 16 ? 166.161 96.645 -79.986 1.00 28.79 ? 24 TYR B CA 1 ATOM 3608 C C . TYR B 1 16 ? 165.548 95.251 -80.089 1.00 29.27 ? 24 TYR B C 1 ATOM 3609 O O . TYR B 1 16 ? 165.098 94.843 -81.166 1.00 29.73 ? 24 TYR B O 1 ATOM 3610 C CB . TYR B 1 16 ? 165.041 97.677 -80.096 1.00 26.63 ? 24 TYR B CB 1 ATOM 3611 C CG . TYR B 1 16 ? 163.941 97.459 -79.080 1.00 24.16 ? 24 TYR B CG 1 ATOM 3612 C CD1 . TYR B 1 16 ? 164.150 97.755 -77.739 1.00 22.48 ? 24 TYR B CD1 1 ATOM 3613 C CD2 . TYR B 1 16 ? 162.711 96.908 -79.452 1.00 23.24 ? 24 TYR B CD2 1 ATOM 3614 C CE1 . TYR B 1 16 ? 163.171 97.510 -76.786 1.00 24.69 ? 24 TYR B CE1 1 ATOM 3615 C CE2 . TYR B 1 16 ? 161.716 96.656 -78.501 1.00 23.66 ? 24 TYR B CE2 1 ATOM 3616 C CZ . TYR B 1 16 ? 161.956 96.961 -77.167 1.00 25.44 ? 24 TYR B CZ 1 ATOM 3617 O OH . TYR B 1 16 ? 160.992 96.722 -76.203 1.00 25.06 ? 24 TYR B OH 1 ATOM 3618 N N . ASN B 1 17 ? 165.533 94.532 -78.967 1.00 27.64 ? 25 ASN B N 1 ATOM 3619 C CA . ASN B 1 17 ? 164.962 93.191 -78.908 1.00 26.52 ? 25 ASN B CA 1 ATOM 3620 C C . ASN B 1 17 ? 165.500 92.301 -80.025 1.00 27.04 ? 25 ASN B C 1 ATOM 3621 O O . ASN B 1 17 ? 164.770 91.478 -80.590 1.00 27.07 ? 25 ASN B O 1 ATOM 3622 C CB . ASN B 1 17 ? 163.441 93.272 -79.013 1.00 24.78 ? 25 ASN B CB 1 ATOM 3623 C CG . ASN B 1 17 ? 162.754 92.128 -78.314 1.00 23.72 ? 25 ASN B CG 1 ATOM 3624 O OD1 . ASN B 1 17 ? 161.764 91.588 -78.808 1.00 24.40 ? 25 ASN B OD1 1 ATOM 3625 N ND2 . ASN B 1 17 ? 163.267 91.755 -77.149 1.00 21.82 ? 25 ASN B ND2 1 ATOM 3626 N N . ALA B 1 18 ? 166.778 92.478 -80.348 1.00 26.53 ? 26 ALA B N 1 ATOM 3627 C CA . ALA B 1 18 ? 167.422 91.693 -81.394 1.00 25.00 ? 26 ALA B CA 1 ATOM 3628 C C . ALA B 1 18 ? 167.450 90.225 -80.997 1.00 23.81 ? 26 ALA B C 1 ATOM 3629 O O . ALA B 1 18 ? 167.816 89.887 -79.879 1.00 22.94 ? 26 ALA B O 1 ATOM 3630 C CB . ALA B 1 18 ? 168.840 92.189 -81.613 1.00 24.86 ? 26 ALA B CB 1 ATOM 3631 N N . PRO B 1 19 ? 167.053 89.331 -81.910 1.00 24.57 ? 27 PRO B N 1 ATOM 3632 C CA . PRO B 1 19 ? 167.059 87.897 -81.598 1.00 25.12 ? 27 PRO B CA 1 ATOM 3633 C C . PRO B 1 19 ? 168.474 87.468 -81.240 1.00 24.65 ? 27 PRO B C 1 ATOM 3634 O O . PRO B 1 19 ? 169.426 87.866 -81.915 1.00 25.79 ? 27 PRO B O 1 ATOM 3635 C CB . PRO B 1 19 ? 166.593 87.261 -82.901 1.00 24.69 ? 27 PRO B CB 1 ATOM 3636 C CG . PRO B 1 19 ? 165.678 88.298 -83.473 1.00 24.38 ? 27 PRO B CG 1 ATOM 3637 C CD . PRO B 1 19 ? 166.430 89.586 -83.220 1.00 25.16 ? 27 PRO B CD 1 ATOM 3638 N N . GLN B 1 20 ? 168.618 86.682 -80.178 1.00 23.55 ? 28 GLN B N 1 ATOM 3639 C CA . GLN B 1 20 ? 169.938 86.203 -79.775 1.00 24.57 ? 28 GLN B CA 1 ATOM 3640 C C . GLN B 1 20 ? 169.867 84.725 -79.384 1.00 24.10 ? 28 GLN B C 1 ATOM 3641 O O . GLN B 1 20 ? 168.776 84.166 -79.256 1.00 25.32 ? 28 GLN B O 1 ATOM 3642 C CB . GLN B 1 20 ? 170.485 87.037 -78.610 1.00 25.32 ? 28 GLN B CB 1 ATOM 3643 C CG . GLN B 1 20 ? 169.797 86.800 -77.275 1.00 28.12 ? 28 GLN B CG 1 ATOM 3644 C CD . GLN B 1 20 ? 170.445 87.575 -76.135 1.00 28.62 ? 28 GLN B CD 1 ATOM 3645 O OE1 . GLN B 1 20 ? 170.284 88.794 -76.029 1.00 32.44 ? 28 GLN B OE1 1 ATOM 3646 N NE2 . GLN B 1 20 ? 171.187 86.873 -75.284 1.00 27.73 ? 28 GLN B NE2 1 ATOM 3647 N N . GLN B 1 21 ? 171.024 84.096 -79.196 1.00 23.64 ? 29 GLN B N 1 ATOM 3648 C CA . GLN B 1 21 ? 171.088 82.678 -78.835 1.00 22.59 ? 29 GLN B CA 1 ATOM 3649 C C . GLN B 1 21 ? 170.292 81.835 -79.827 1.00 21.82 ? 29 GLN B C 1 ATOM 3650 O O . GLN B 1 21 ? 169.547 80.943 -79.437 1.00 22.06 ? 29 GLN B O 1 ATOM 3651 C CB . GLN B 1 21 ? 170.530 82.455 -77.426 1.00 21.34 ? 29 GLN B CB 1 ATOM 3652 C CG . GLN B 1 21 ? 171.263 83.204 -76.329 1.00 21.80 ? 29 GLN B CG 1 ATOM 3653 C CD . GLN B 1 21 ? 170.696 82.896 -74.959 1.00 23.03 ? 29 GLN B CD 1 ATOM 3654 O OE1 . GLN B 1 21 ? 170.591 81.733 -74.574 1.00 24.81 ? 29 GLN B OE1 1 ATOM 3655 N NE2 . GLN B 1 21 ? 170.327 83.936 -74.213 1.00 23.43 ? 29 GLN B NE2 1 ATOM 3656 N N . VAL B 1 22 ? 170.451 82.127 -81.111 1.00 22.10 ? 30 VAL B N 1 ATOM 3657 C CA . VAL B 1 22 ? 169.744 81.408 -82.161 1.00 22.63 ? 30 VAL B CA 1 ATOM 3658 C C . VAL B 1 22 ? 170.394 80.041 -82.389 1.00 23.58 ? 30 VAL B C 1 ATOM 3659 O O . VAL B 1 22 ? 171.620 79.918 -82.390 1.00 24.02 ? 30 VAL B O 1 ATOM 3660 C CB . VAL B 1 22 ? 169.764 82.230 -83.474 1.00 23.89 ? 30 VAL B CB 1 ATOM 3661 C CG1 . VAL B 1 22 ? 169.011 81.501 -84.576 1.00 22.21 ? 30 VAL B CG1 1 ATOM 3662 C CG2 . VAL B 1 22 ? 169.148 83.607 -83.231 1.00 24.12 ? 30 VAL B CG2 1 ATOM 3663 N N . HIS B 1 23 ? 169.565 79.014 -82.555 1.00 23.21 ? 31 HIS B N 1 ATOM 3664 C CA . HIS B 1 23 ? 170.056 77.662 -82.788 1.00 23.21 ? 31 HIS B CA 1 ATOM 3665 C C . HIS B 1 23 ? 168.973 76.808 -83.441 1.00 22.19 ? 31 HIS B C 1 ATOM 3666 O O . HIS B 1 23 ? 167.778 77.023 -83.200 1.00 21.58 ? 31 HIS B O 1 ATOM 3667 C CB . HIS B 1 23 ? 170.562 77.027 -81.473 1.00 23.29 ? 31 HIS B CB 1 ATOM 3668 C CG . HIS B 1 23 ? 169.622 77.162 -80.310 1.00 24.02 ? 31 HIS B CG 1 ATOM 3669 N ND1 . HIS B 1 23 ? 168.801 76.137 -79.888 1.00 24.51 ? 31 HIS B ND1 1 ATOM 3670 C CD2 . HIS B 1 23 ? 169.411 78.187 -79.449 1.00 22.61 ? 31 HIS B CD2 1 ATOM 3671 C CE1 . HIS B 1 23 ? 168.130 76.521 -78.816 1.00 22.15 ? 31 HIS B CE1 1 ATOM 3672 N NE2 . HIS B 1 23 ? 168.482 77.761 -78.528 1.00 21.08 ? 31 HIS B NE2 1 ATOM 3673 N N . ILE B 1 24 ? 169.394 75.863 -84.286 1.00 21.68 ? 32 ILE B N 1 ATOM 3674 C CA . ILE B 1 24 ? 168.465 74.992 -85.006 1.00 20.92 ? 32 ILE B CA 1 ATOM 3675 C C . ILE B 1 24 ? 168.759 73.498 -84.819 1.00 20.77 ? 32 ILE B C 1 ATOM 3676 O O . ILE B 1 24 ? 169.862 73.126 -84.421 1.00 19.75 ? 32 ILE B O 1 ATOM 3677 C CB . ILE B 1 24 ? 168.491 75.305 -86.538 1.00 21.26 ? 32 ILE B CB 1 ATOM 3678 C CG1 . ILE B 1 24 ? 169.824 74.869 -87.154 1.00 20.17 ? 32 ILE B CG1 1 ATOM 3679 C CG2 . ILE B 1 24 ? 168.294 76.796 -86.767 1.00 19.16 ? 32 ILE B CG2 1 ATOM 3680 C CD1 . ILE B 1 24 ? 169.855 74.925 -88.671 1.00 20.05 ? 32 ILE B CD1 1 ATOM 3681 N N . THR B 1 25 ? 167.765 72.652 -85.101 1.00 21.16 ? 33 THR B N 1 ATOM 3682 C CA . THR B 1 25 ? 167.914 71.197 -85.017 1.00 22.47 ? 33 THR B CA 1 ATOM 3683 C C . THR B 1 25 ? 166.881 70.584 -85.935 1.00 22.22 ? 33 THR B C 1 ATOM 3684 O O . THR B 1 25 ? 165.889 71.222 -86.284 1.00 23.00 ? 33 THR B O 1 ATOM 3685 C CB . THR B 1 25 ? 167.611 70.627 -83.621 1.00 25.37 ? 33 THR B CB 1 ATOM 3686 O OG1 . THR B 1 25 ? 168.207 71.454 -82.624 1.00 34.58 ? 33 THR B OG1 1 ATOM 3687 C CG2 . THR B 1 25 ? 168.191 69.228 -83.486 1.00 23.86 ? 33 THR B CG2 1 ATOM 3688 N N . GLN B 1 26 ? 167.104 69.339 -86.323 1.00 21.20 ? 34 GLN B N 1 ATOM 3689 C CA . GLN B 1 26 ? 166.156 68.661 -87.184 1.00 21.19 ? 34 GLN B CA 1 ATOM 3690 C C . GLN B 1 26 ? 164.816 68.625 -86.454 1.00 22.44 ? 34 GLN B C 1 ATOM 3691 O O . GLN B 1 26 ? 164.756 68.321 -85.257 1.00 22.86 ? 34 GLN B O 1 ATOM 3692 C CB . GLN B 1 26 ? 166.651 67.255 -87.474 1.00 19.33 ? 34 GLN B CB 1 ATOM 3693 C CG . GLN B 1 26 ? 165.732 66.459 -88.343 1.00 19.94 ? 34 GLN B CG 1 ATOM 3694 C CD . GLN B 1 26 ? 166.453 65.318 -89.015 1.00 19.82 ? 34 GLN B CD 1 ATOM 3695 O OE1 . GLN B 1 26 ? 165.896 64.230 -89.170 1.00 19.94 ? 34 GLN B OE1 1 ATOM 3696 N NE2 . GLN B 1 26 ? 167.695 65.560 -89.433 1.00 15.03 ? 34 GLN B NE2 1 ATOM 3697 N N . GLY B 1 27 ? 163.742 68.940 -87.171 1.00 22.14 ? 35 GLY B N 1 ATOM 3698 C CA . GLY B 1 27 ? 162.432 68.961 -86.542 1.00 21.95 ? 35 GLY B CA 1 ATOM 3699 C C . GLY B 1 27 ? 161.510 67.798 -86.851 1.00 22.21 ? 35 GLY B C 1 ATOM 3700 O O . GLY B 1 27 ? 160.353 67.792 -86.425 1.00 21.93 ? 35 GLY B O 1 ATOM 3701 N N . ASP B 1 28 ? 162.005 66.819 -87.596 1.00 22.87 ? 36 ASP B N 1 ATOM 3702 C CA . ASP B 1 28 ? 161.195 65.655 -87.932 1.00 24.23 ? 36 ASP B CA 1 ATOM 3703 C C . ASP B 1 28 ? 162.082 64.423 -88.044 1.00 25.44 ? 36 ASP B C 1 ATOM 3704 O O . ASP B 1 28 ? 163.299 64.496 -87.848 1.00 25.87 ? 36 ASP B O 1 ATOM 3705 C CB . ASP B 1 28 ? 160.443 65.889 -89.245 1.00 24.17 ? 36 ASP B CB 1 ATOM 3706 C CG . ASP B 1 28 ? 161.360 65.879 -90.453 1.00 24.64 ? 36 ASP B CG 1 ATOM 3707 O OD1 . ASP B 1 28 ? 162.566 66.168 -90.295 1.00 24.23 ? 36 ASP B OD1 1 ATOM 3708 O OD2 . ASP B 1 28 ? 160.869 65.594 -91.566 1.00 25.56 ? 36 ASP B OD2 1 ATOM 3709 N N . LEU B 1 29 ? 161.466 63.297 -88.378 1.00 25.97 ? 37 LEU B N 1 ATOM 3710 C CA . LEU B 1 29 ? 162.172 62.031 -88.492 1.00 25.71 ? 37 LEU B CA 1 ATOM 3711 C C . LEU B 1 29 ? 163.106 61.872 -89.688 1.00 26.51 ? 37 LEU B C 1 ATOM 3712 O O . LEU B 1 29 ? 164.206 61.338 -89.543 1.00 26.33 ? 37 LEU B O 1 ATOM 3713 C CB . LEU B 1 29 ? 161.157 60.893 -88.508 1.00 24.13 ? 37 LEU B CB 1 ATOM 3714 C CG . LEU B 1 29 ? 161.729 59.485 -88.388 1.00 23.67 ? 37 LEU B CG 1 ATOM 3715 C CD1 . LEU B 1 29 ? 162.495 59.368 -87.087 1.00 23.65 ? 37 LEU B CD1 1 ATOM 3716 C CD2 . LEU B 1 29 ? 160.603 58.477 -88.434 1.00 22.21 ? 37 LEU B CD2 1 ATOM 3717 N N . VAL B 1 30 ? 162.680 62.336 -90.861 1.00 28.09 ? 38 VAL B N 1 ATOM 3718 C CA . VAL B 1 30 ? 163.472 62.171 -92.084 1.00 28.59 ? 38 VAL B CA 1 ATOM 3719 C C . VAL B 1 30 ? 164.344 63.333 -92.532 1.00 28.70 ? 38 VAL B C 1 ATOM 3720 O O . VAL B 1 30 ? 165.140 63.180 -93.462 1.00 30.46 ? 38 VAL B O 1 ATOM 3721 C CB . VAL B 1 30 ? 162.570 61.800 -93.265 1.00 28.33 ? 38 VAL B CB 1 ATOM 3722 C CG1 . VAL B 1 30 ? 161.808 60.535 -92.946 1.00 28.00 ? 38 VAL B CG1 1 ATOM 3723 C CG2 . VAL B 1 30 ? 161.614 62.943 -93.560 1.00 29.34 ? 38 VAL B CG2 1 ATOM 3724 N N . GLY B 1 31 ? 164.180 64.493 -91.908 1.00 28.44 ? 39 GLY B N 1 ATOM 3725 C CA . GLY B 1 31 ? 165.007 65.625 -92.276 1.00 27.20 ? 39 GLY B CA 1 ATOM 3726 C C . GLY B 1 31 ? 164.388 66.726 -93.118 1.00 28.43 ? 39 GLY B C 1 ATOM 3727 O O . GLY B 1 31 ? 165.113 67.536 -93.697 1.00 28.29 ? 39 GLY B O 1 ATOM 3728 N N . ARG B 1 32 ? 163.068 66.783 -93.216 1.00 28.10 ? 40 ARG B N 1 ATOM 3729 C CA . ARG B 1 32 ? 162.485 67.858 -93.999 1.00 29.83 ? 40 ARG B CA 1 ATOM 3730 C C . ARG B 1 32 ? 161.720 68.823 -93.104 1.00 29.53 ? 40 ARG B C 1 ATOM 3731 O O . ARG B 1 32 ? 160.677 69.372 -93.487 1.00 29.71 ? 40 ARG B O 1 ATOM 3732 C CB . ARG B 1 32 ? 161.583 67.312 -95.102 1.00 32.84 ? 40 ARG B CB 1 ATOM 3733 C CG . ARG B 1 32 ? 160.413 66.504 -94.625 1.00 39.22 ? 40 ARG B CG 1 ATOM 3734 C CD . ARG B 1 32 ? 159.420 66.394 -95.755 1.00 44.44 ? 40 ARG B CD 1 ATOM 3735 N NE . ARG B 1 32 ? 160.054 65.921 -96.982 1.00 47.68 ? 40 ARG B NE 1 ATOM 3736 C CZ . ARG B 1 32 ? 159.651 66.267 -98.200 1.00 50.89 ? 40 ARG B CZ 1 ATOM 3737 N NH1 . ARG B 1 32 ? 158.620 67.094 -98.343 1.00 51.19 ? 40 ARG B NH1 1 ATOM 3738 N NH2 . ARG B 1 32 ? 160.263 65.777 -99.273 1.00 51.62 ? 40 ARG B NH2 1 ATOM 3739 N N . ALA B 1 33 ? 162.266 69.025 -91.908 1.00 27.57 ? 41 ALA B N 1 ATOM 3740 C CA . ALA B 1 33 ? 161.698 69.926 -90.917 1.00 25.63 ? 41 ALA B CA 1 ATOM 3741 C C . ALA B 1 33 ? 162.856 70.437 -90.074 1.00 25.72 ? 41 ALA B C 1 ATOM 3742 O O . ALA B 1 33 ? 163.891 69.783 -89.949 1.00 26.46 ? 41 ALA B O 1 ATOM 3743 C CB . ALA B 1 33 ? 160.694 69.197 -90.051 1.00 24.75 ? 41 ALA B CB 1 ATOM 3744 N N . MET B 1 34 ? 162.681 71.611 -89.490 1.00 25.60 ? 42 MET B N 1 ATOM 3745 C CA . MET B 1 34 ? 163.735 72.205 -88.685 1.00 25.09 ? 42 MET B CA 1 ATOM 3746 C C . MET B 1 34 ? 163.124 72.999 -87.530 1.00 24.17 ? 42 MET B C 1 ATOM 3747 O O . MET B 1 34 ? 162.127 73.696 -87.703 1.00 25.61 ? 42 MET B O 1 ATOM 3748 C CB . MET B 1 34 ? 164.559 73.135 -89.573 1.00 25.79 ? 42 MET B CB 1 ATOM 3749 C CG . MET B 1 34 ? 165.918 73.509 -89.045 1.00 27.74 ? 42 MET B CG 1 ATOM 3750 S SD . MET B 1 34 ? 167.055 72.136 -89.216 1.00 31.14 ? 42 MET B SD 1 ATOM 3751 C CE . MET B 1 34 ? 167.311 72.134 -90.967 1.00 29.11 ? 42 MET B CE 1 ATOM 3752 N N . ILE B 1 35 ? 163.700 72.881 -86.344 1.00 23.33 ? 43 ILE B N 1 ATOM 3753 C CA . ILE B 1 35 ? 163.197 73.641 -85.205 1.00 21.59 ? 43 ILE B CA 1 ATOM 3754 C C . ILE B 1 35 ? 164.099 74.857 -85.048 1.00 22.67 ? 43 ILE B C 1 ATOM 3755 O O . ILE B 1 35 ? 165.304 74.713 -84.830 1.00 22.78 ? 43 ILE B O 1 ATOM 3756 C CB . ILE B 1 35 ? 163.240 72.831 -83.889 1.00 20.30 ? 43 ILE B CB 1 ATOM 3757 C CG1 . ILE B 1 35 ? 162.278 71.645 -83.962 1.00 17.95 ? 43 ILE B CG1 1 ATOM 3758 C CG2 . ILE B 1 35 ? 162.867 73.727 -82.712 1.00 18.03 ? 43 ILE B CG2 1 ATOM 3759 C CD1 . ILE B 1 35 ? 162.368 70.716 -82.764 1.00 14.73 ? 43 ILE B CD1 1 ATOM 3760 N N . ILE B 1 36 ? 163.518 76.047 -85.183 1.00 22.58 ? 44 ILE B N 1 ATOM 3761 C CA . ILE B 1 36 ? 164.263 77.291 -85.036 1.00 22.45 ? 44 ILE B CA 1 ATOM 3762 C C . ILE B 1 36 ? 164.009 77.819 -83.619 1.00 22.68 ? 44 ILE B C 1 ATOM 3763 O O . ILE B 1 36 ? 162.859 77.968 -83.199 1.00 22.56 ? 44 ILE B O 1 ATOM 3764 C CB . ILE B 1 36 ? 163.806 78.348 -86.078 1.00 21.07 ? 44 ILE B CB 1 ATOM 3765 C CG1 . ILE B 1 36 ? 163.800 77.740 -87.487 1.00 19.98 ? 44 ILE B CG1 1 ATOM 3766 C CG2 . ILE B 1 36 ? 164.724 79.555 -86.027 1.00 20.58 ? 44 ILE B CG2 1 ATOM 3767 C CD1 . ILE B 1 36 ? 165.108 77.127 -87.925 1.00 17.29 ? 44 ILE B CD1 1 ATOM 3768 N N . SER B 1 37 ? 165.087 78.084 -82.884 1.00 23.35 ? 45 SER B N 1 ATOM 3769 C CA . SER B 1 37 ? 164.986 78.574 -81.510 1.00 24.19 ? 45 SER B CA 1 ATOM 3770 C C . SER B 1 37 ? 165.816 79.828 -81.269 1.00 24.28 ? 45 SER B C 1 ATOM 3771 O O . SER B 1 37 ? 166.917 79.972 -81.804 1.00 25.60 ? 45 SER B O 1 ATOM 3772 C CB . SER B 1 37 ? 165.459 77.502 -80.525 1.00 23.48 ? 45 SER B CB 1 ATOM 3773 O OG . SER B 1 37 ? 164.704 76.314 -80.640 1.00 26.60 ? 45 SER B OG 1 ATOM 3774 N N . TRP B 1 38 ? 165.294 80.728 -80.443 1.00 23.75 ? 46 TRP B N 1 ATOM 3775 C CA . TRP B 1 38 ? 166.015 81.951 -80.120 1.00 24.00 ? 46 TRP B CA 1 ATOM 3776 C C . TRP B 1 38 ? 165.440 82.624 -78.877 1.00 24.04 ? 46 TRP B C 1 ATOM 3777 O O . TRP B 1 38 ? 164.388 82.223 -78.373 1.00 23.93 ? 46 TRP B O 1 ATOM 3778 C CB . TRP B 1 38 ? 165.992 82.915 -81.313 1.00 23.41 ? 46 TRP B CB 1 ATOM 3779 C CG . TRP B 1 38 ? 164.680 83.594 -81.558 1.00 22.12 ? 46 TRP B CG 1 ATOM 3780 C CD1 . TRP B 1 38 ? 164.333 84.866 -81.187 1.00 21.80 ? 46 TRP B CD1 1 ATOM 3781 C CD2 . TRP B 1 38 ? 163.557 83.060 -82.274 1.00 19.93 ? 46 TRP B CD2 1 ATOM 3782 N NE1 . TRP B 1 38 ? 163.064 85.157 -81.639 1.00 22.30 ? 46 TRP B NE1 1 ATOM 3783 C CE2 . TRP B 1 38 ? 162.566 84.067 -82.307 1.00 20.40 ? 46 TRP B CE2 1 ATOM 3784 C CE3 . TRP B 1 38 ? 163.292 81.828 -82.888 1.00 18.71 ? 46 TRP B CE3 1 ATOM 3785 C CZ2 . TRP B 1 38 ? 161.325 83.877 -82.936 1.00 19.39 ? 46 TRP B CZ2 1 ATOM 3786 C CZ3 . TRP B 1 38 ? 162.056 81.639 -83.512 1.00 18.38 ? 46 TRP B CZ3 1 ATOM 3787 C CH2 . TRP B 1 38 ? 161.090 82.659 -83.530 1.00 17.72 ? 46 TRP B CH2 1 ATOM 3788 N N . VAL B 1 39 ? 166.144 83.635 -78.381 1.00 22.85 ? 47 VAL B N 1 ATOM 3789 C CA . VAL B 1 39 ? 165.712 84.362 -77.202 1.00 22.92 ? 47 VAL B CA 1 ATOM 3790 C C . VAL B 1 39 ? 165.649 85.859 -77.478 1.00 24.49 ? 47 VAL B C 1 ATOM 3791 O O . VAL B 1 39 ? 166.402 86.376 -78.300 1.00 26.69 ? 47 VAL B O 1 ATOM 3792 C CB . VAL B 1 39 ? 166.701 84.169 -76.042 1.00 21.30 ? 47 VAL B CB 1 ATOM 3793 C CG1 . VAL B 1 39 ? 166.208 84.908 -74.813 1.00 21.64 ? 47 VAL B CG1 1 ATOM 3794 C CG2 . VAL B 1 39 ? 166.887 82.706 -75.752 1.00 20.49 ? 47 VAL B CG2 1 ATOM 3795 N N . THR B 1 40 ? 164.744 86.553 -76.797 1.00 24.04 ? 48 THR B N 1 ATOM 3796 C CA . THR B 1 40 ? 164.650 88.002 -76.919 1.00 23.76 ? 48 THR B CA 1 ATOM 3797 C C . THR B 1 40 ? 164.627 88.496 -75.473 1.00 23.91 ? 48 THR B C 1 ATOM 3798 O O . THR B 1 40 ? 163.973 87.892 -74.626 1.00 24.42 ? 48 THR B O 1 ATOM 3799 C CB . THR B 1 40 ? 163.381 88.446 -77.671 1.00 23.02 ? 48 THR B CB 1 ATOM 3800 O OG1 . THR B 1 40 ? 162.229 87.839 -77.084 1.00 23.65 ? 48 THR B OG1 1 ATOM 3801 C CG2 . THR B 1 40 ? 163.462 88.046 -79.127 1.00 22.83 ? 48 THR B CG2 1 ATOM 3802 N N . MET B 1 41 ? 165.352 89.570 -75.181 1.00 24.10 ? 49 MET B N 1 ATOM 3803 C CA . MET B 1 41 ? 165.415 90.081 -73.819 1.00 25.49 ? 49 MET B CA 1 ATOM 3804 C C . MET B 1 41 ? 164.582 91.323 -73.533 1.00 26.30 ? 49 MET B C 1 ATOM 3805 O O . MET B 1 41 ? 164.061 91.486 -72.430 1.00 27.25 ? 49 MET B O 1 ATOM 3806 C CB . MET B 1 41 ? 166.864 90.382 -73.450 1.00 27.18 ? 49 MET B CB 1 ATOM 3807 C CG . MET B 1 41 ? 167.793 89.198 -73.547 1.00 31.62 ? 49 MET B CG 1 ATOM 3808 S SD . MET B 1 41 ? 167.575 88.005 -72.215 1.00 34.35 ? 49 MET B SD 1 ATOM 3809 C CE . MET B 1 41 ? 169.250 87.300 -72.135 1.00 33.91 ? 49 MET B CE 1 ATOM 3810 N N . ASP B 1 42 ? 164.459 92.207 -74.512 1.00 26.86 ? 50 ASP B N 1 ATOM 3811 C CA . ASP B 1 42 ? 163.720 93.440 -74.293 1.00 27.64 ? 50 ASP B CA 1 ATOM 3812 C C . ASP B 1 42 ? 162.217 93.269 -74.117 1.00 26.69 ? 50 ASP B C 1 ATOM 3813 O O . ASP B 1 42 ? 161.616 93.909 -73.260 1.00 27.56 ? 50 ASP B O 1 ATOM 3814 C CB . ASP B 1 42 ? 164.045 94.432 -75.408 1.00 29.95 ? 50 ASP B CB 1 ATOM 3815 C CG . ASP B 1 42 ? 165.526 94.783 -75.441 1.00 31.81 ? 50 ASP B CG 1 ATOM 3816 O OD1 . ASP B 1 42 ? 166.080 95.036 -74.350 1.00 31.18 ? 50 ASP B OD1 1 ATOM 3817 O OD2 . ASP B 1 42 ? 166.135 94.800 -76.538 1.00 34.64 ? 50 ASP B OD2 1 ATOM 3818 N N . GLU B 1 43 ? 161.604 92.413 -74.920 1.00 25.59 ? 51 GLU B N 1 ATOM 3819 C CA . GLU B 1 43 ? 160.177 92.159 -74.783 1.00 26.24 ? 51 GLU B CA 1 ATOM 3820 C C . GLU B 1 43 ? 159.821 90.871 -75.506 1.00 26.95 ? 51 GLU B C 1 ATOM 3821 O O . GLU B 1 43 ? 160.618 90.360 -76.291 1.00 27.43 ? 51 GLU B O 1 ATOM 3822 C CB . GLU B 1 43 ? 159.345 93.325 -75.327 1.00 25.03 ? 51 GLU B CB 1 ATOM 3823 C CG . GLU B 1 43 ? 159.538 93.624 -76.790 1.00 26.59 ? 51 GLU B CG 1 ATOM 3824 C CD . GLU B 1 43 ? 158.562 94.676 -77.284 1.00 28.29 ? 51 GLU B CD 1 ATOM 3825 O OE1 . GLU B 1 43 ? 157.487 94.313 -77.816 1.00 28.52 ? 51 GLU B OE1 1 ATOM 3826 O OE2 . GLU B 1 43 ? 158.862 95.875 -77.123 1.00 29.77 ? 51 GLU B OE2 1 ATOM 3827 N N . PRO B 1 44 ? 158.623 90.324 -75.246 1.00 26.81 ? 52 PRO B N 1 ATOM 3828 C CA . PRO B 1 44 ? 158.203 89.084 -75.896 1.00 27.12 ? 52 PRO B CA 1 ATOM 3829 C C . PRO B 1 44 ? 158.565 88.959 -77.381 1.00 27.98 ? 52 PRO B C 1 ATOM 3830 O O . PRO B 1 44 ? 159.289 88.039 -77.767 1.00 29.58 ? 52 PRO B O 1 ATOM 3831 C CB . PRO B 1 44 ? 156.705 89.063 -75.625 1.00 26.51 ? 52 PRO B CB 1 ATOM 3832 C CG . PRO B 1 44 ? 156.650 89.607 -74.226 1.00 25.84 ? 52 PRO B CG 1 ATOM 3833 C CD . PRO B 1 44 ? 157.579 90.805 -74.320 1.00 27.11 ? 52 PRO B CD 1 ATOM 3834 N N . GLY B 1 45 ? 158.084 89.875 -78.214 1.00 28.26 ? 53 GLY B N 1 ATOM 3835 C CA . GLY B 1 45 ? 158.404 89.797 -79.631 1.00 27.72 ? 53 GLY B CA 1 ATOM 3836 C C . GLY B 1 45 ? 157.570 88.740 -80.329 1.00 27.79 ? 53 GLY B C 1 ATOM 3837 O O . GLY B 1 45 ? 156.782 88.047 -79.682 1.00 27.96 ? 53 GLY B O 1 ATOM 3838 N N . SER B 1 46 ? 157.737 88.609 -81.644 1.00 27.82 ? 54 SER B N 1 ATOM 3839 C CA . SER B 1 46 ? 156.974 87.628 -82.422 1.00 28.18 ? 54 SER B CA 1 ATOM 3840 C C . SER B 1 46 ? 157.656 86.266 -82.458 1.00 28.14 ? 54 SER B C 1 ATOM 3841 O O . SER B 1 46 ? 158.882 86.179 -82.410 1.00 27.42 ? 54 SER B O 1 ATOM 3842 C CB . SER B 1 46 ? 156.784 88.120 -83.860 1.00 27.71 ? 54 SER B CB 1 ATOM 3843 O OG . SER B 1 46 ? 156.111 87.149 -84.648 1.00 27.15 ? 54 SER B OG 1 ATOM 3844 N N . SER B 1 47 ? 156.861 85.204 -82.542 1.00 27.53 ? 55 SER B N 1 ATOM 3845 C CA . SER B 1 47 ? 157.431 83.863 -82.605 1.00 29.31 ? 55 SER B CA 1 ATOM 3846 C C . SER B 1 47 ? 157.351 83.384 -84.043 1.00 30.01 ? 55 SER B C 1 ATOM 3847 O O . SER B 1 47 ? 157.341 82.185 -84.312 1.00 30.69 ? 55 SER B O 1 ATOM 3848 C CB . SER B 1 47 ? 156.674 82.898 -81.686 1.00 28.92 ? 55 SER B CB 1 ATOM 3849 O OG . SER B 1 47 ? 156.829 83.265 -80.326 1.00 28.55 ? 55 SER B OG 1 ATOM 3850 N N . ALA B 1 48 ? 157.298 84.339 -84.966 1.00 30.04 ? 56 ALA B N 1 ATOM 3851 C CA . ALA B 1 48 ? 157.212 84.017 -86.377 1.00 29.47 ? 56 ALA B CA 1 ATOM 3852 C C . ALA B 1 48 ? 158.594 83.832 -86.974 1.00 29.55 ? 56 ALA B C 1 ATOM 3853 O O . ALA B 1 48 ? 159.569 84.434 -86.525 1.00 29.05 ? 56 ALA B O 1 ATOM 3854 C CB . ALA B 1 48 ? 156.471 85.115 -87.124 1.00 28.40 ? 56 ALA B CB 1 ATOM 3855 N N . VAL B 1 49 ? 158.666 82.986 -87.990 1.00 29.26 ? 57 VAL B N 1 ATOM 3856 C CA . VAL B 1 49 ? 159.910 82.729 -88.680 1.00 29.99 ? 57 VAL B CA 1 ATOM 3857 C C . VAL B 1 49 ? 159.589 82.842 -90.160 1.00 31.28 ? 57 VAL B C 1 ATOM 3858 O O . VAL B 1 49 ? 158.692 82.158 -90.663 1.00 31.24 ? 57 VAL B O 1 ATOM 3859 C CB . VAL B 1 49 ? 160.447 81.313 -88.369 1.00 30.54 ? 57 VAL B CB 1 ATOM 3860 C CG1 . VAL B 1 49 ? 161.706 81.040 -89.182 1.00 29.17 ? 57 VAL B CG1 1 ATOM 3861 C CG2 . VAL B 1 49 ? 160.749 81.191 -86.882 1.00 30.22 ? 57 VAL B CG2 1 ATOM 3862 N N . ARG B 1 50 ? 160.301 83.732 -90.844 1.00 31.54 ? 58 ARG B N 1 ATOM 3863 C CA . ARG B 1 50 ? 160.103 83.936 -92.268 1.00 32.31 ? 58 ARG B CA 1 ATOM 3864 C C . ARG B 1 50 ? 161.250 83.229 -92.969 1.00 32.55 ? 58 ARG B C 1 ATOM 3865 O O . ARG B 1 50 ? 162.417 83.453 -92.648 1.00 33.34 ? 58 ARG B O 1 ATOM 3866 C CB . ARG B 1 50 ? 160.103 85.437 -92.588 1.00 33.99 ? 58 ARG B CB 1 ATOM 3867 C CG . ARG B 1 50 ? 159.835 85.793 -94.052 1.00 35.82 ? 58 ARG B CG 1 ATOM 3868 C CD . ARG B 1 50 ? 159.302 87.219 -94.180 1.00 36.62 ? 58 ARG B CD 1 ATOM 3869 N NE . ARG B 1 50 ? 160.200 88.206 -93.581 1.00 38.49 ? 58 ARG B NE 1 ATOM 3870 C CZ . ARG B 1 50 ? 159.793 89.360 -93.053 1.00 39.47 ? 58 ARG B CZ 1 ATOM 3871 N NH1 . ARG B 1 50 ? 158.502 89.666 -93.049 1.00 40.12 ? 58 ARG B NH1 1 ATOM 3872 N NH2 . ARG B 1 50 ? 160.671 90.207 -92.522 1.00 39.32 ? 58 ARG B NH2 1 ATOM 3873 N N . TYR B 1 51 ? 160.919 82.360 -93.913 1.00 32.27 ? 59 TYR B N 1 ATOM 3874 C CA . TYR B 1 51 ? 161.940 81.617 -94.632 1.00 32.21 ? 59 TYR B CA 1 ATOM 3875 C C . TYR B 1 51 ? 161.596 81.470 -96.109 1.00 33.12 ? 59 TYR B C 1 ATOM 3876 O O . TYR B 1 51 ? 160.444 81.633 -96.511 1.00 32.73 ? 59 TYR B O 1 ATOM 3877 C CB . TYR B 1 51 ? 162.105 80.229 -94.014 1.00 30.64 ? 59 TYR B CB 1 ATOM 3878 C CG . TYR B 1 51 ? 160.857 79.381 -94.108 1.00 29.82 ? 59 TYR B CG 1 ATOM 3879 C CD1 . TYR B 1 51 ? 159.754 79.636 -93.295 1.00 28.46 ? 59 TYR B CD1 1 ATOM 3880 C CD2 . TYR B 1 51 ? 160.771 78.334 -95.026 1.00 29.26 ? 59 TYR B CD2 1 ATOM 3881 C CE1 . TYR B 1 51 ? 158.604 78.875 -93.392 1.00 27.94 ? 59 TYR B CE1 1 ATOM 3882 C CE2 . TYR B 1 51 ? 159.620 77.563 -95.130 1.00 29.00 ? 59 TYR B CE2 1 ATOM 3883 C CZ . TYR B 1 51 ? 158.543 77.838 -94.309 1.00 29.44 ? 59 TYR B CZ 1 ATOM 3884 O OH . TYR B 1 51 ? 157.409 77.066 -94.398 1.00 30.95 ? 59 TYR B OH 1 ATOM 3885 N N . TRP B 1 52 ? 162.608 81.145 -96.907 1.00 34.98 ? 60 TRP B N 1 ATOM 3886 C CA . TRP B 1 52 ? 162.442 80.970 -98.342 1.00 36.12 ? 60 TRP B CA 1 ATOM 3887 C C . TRP B 1 52 ? 163.685 80.271 -98.900 1.00 38.63 ? 60 TRP B C 1 ATOM 3888 O O . TRP B 1 52 ? 164.785 80.428 -98.355 1.00 38.21 ? 60 TRP B O 1 ATOM 3889 C CB . TRP B 1 52 ? 162.250 82.343 -99.000 1.00 34.28 ? 60 TRP B CB 1 ATOM 3890 C CG . TRP B 1 52 ? 163.453 83.261 -98.888 1.00 32.00 ? 60 TRP B CG 1 ATOM 3891 C CD1 . TRP B 1 52 ? 164.499 83.346 -99.761 1.00 33.65 ? 60 TRP B CD1 1 ATOM 3892 C CD2 . TRP B 1 52 ? 163.723 84.216 -97.852 1.00 31.87 ? 60 TRP B CD2 1 ATOM 3893 N NE1 . TRP B 1 52 ? 165.402 84.295 -99.339 1.00 32.23 ? 60 TRP B NE1 1 ATOM 3894 C CE2 . TRP B 1 52 ? 164.952 84.844 -98.171 1.00 31.35 ? 60 TRP B CE2 1 ATOM 3895 C CE3 . TRP B 1 52 ? 163.049 84.605 -96.688 1.00 31.46 ? 60 TRP B CE3 1 ATOM 3896 C CZ2 . TRP B 1 52 ? 165.520 85.837 -97.369 1.00 31.13 ? 60 TRP B CZ2 1 ATOM 3897 C CZ3 . TRP B 1 52 ? 163.615 85.596 -95.889 1.00 31.72 ? 60 TRP B CZ3 1 ATOM 3898 C CH2 . TRP B 1 52 ? 164.840 86.200 -96.236 1.00 31.57 ? 60 TRP B CH2 1 ATOM 3899 N N . SER B 1 53 ? 163.514 79.493 -99.969 1.00 41.24 ? 61 SER B N 1 ATOM 3900 C CA . SER B 1 53 ? 164.643 78.797 -100.581 1.00 44.23 ? 61 SER B CA 1 ATOM 3901 C C . SER B 1 53 ? 165.391 79.724 -101.528 1.00 47.70 ? 61 SER B C 1 ATOM 3902 O O . SER B 1 53 ? 164.796 80.617 -102.130 1.00 47.59 ? 61 SER B O 1 ATOM 3903 C CB . SER B 1 53 ? 164.167 77.547 -101.330 1.00 42.87 ? 61 SER B CB 1 ATOM 3904 O OG . SER B 1 53 ? 163.014 77.809 -102.107 1.00 41.79 ? 61 SER B OG 1 ATOM 3905 N N . GLU B 1 54 ? 166.698 79.509 -101.652 1.00 52.44 ? 62 GLU B N 1 ATOM 3906 C CA . GLU B 1 54 ? 167.543 80.331 -102.514 1.00 57.50 ? 62 GLU B CA 1 ATOM 3907 C C . GLU B 1 54 ? 166.965 80.452 -103.923 1.00 60.35 ? 62 GLU B C 1 ATOM 3908 O O . GLU B 1 54 ? 166.938 81.545 -104.503 1.00 61.03 ? 62 GLU B O 1 ATOM 3909 C CB . GLU B 1 54 ? 168.953 79.741 -102.569 1.00 58.88 ? 62 GLU B CB 1 ATOM 3910 C CG . GLU B 1 54 ? 169.993 80.671 -103.175 1.00 62.32 ? 62 GLU B CG 1 ATOM 3911 C CD . GLU B 1 54 ? 171.413 80.216 -102.886 1.00 64.90 ? 62 GLU B CD 1 ATOM 3912 O OE1 . GLU B 1 54 ? 171.730 79.038 -103.174 1.00 65.93 ? 62 GLU B OE1 1 ATOM 3913 O OE2 . GLU B 1 54 ? 172.208 81.035 -102.367 1.00 65.78 ? 62 GLU B OE2 1 ATOM 3914 N N . LYS B 1 55 ? 166.508 79.329 -104.471 1.00 62.90 ? 63 LYS B N 1 ATOM 3915 C CA . LYS B 1 55 ? 165.909 79.312 -105.803 1.00 65.76 ? 63 LYS B CA 1 ATOM 3916 C C . LYS B 1 55 ? 164.531 79.981 -105.770 1.00 66.85 ? 63 LYS B C 1 ATOM 3917 O O . LYS B 1 55 ? 164.403 81.165 -106.093 1.00 67.00 ? 63 LYS B O 1 ATOM 3918 C CB . LYS B 1 55 ? 165.786 77.867 -106.308 1.00 67.53 ? 63 LYS B CB 1 ATOM 3919 C CG . LYS B 1 55 ? 165.511 76.836 -105.216 1.00 69.85 ? 63 LYS B CG 1 ATOM 3920 C CD . LYS B 1 55 ? 165.164 75.462 -105.795 1.00 71.95 ? 63 LYS B CD 1 ATOM 3921 C CE . LYS B 1 55 ? 163.745 75.435 -106.370 1.00 72.95 ? 63 LYS B CE 1 ATOM 3922 N NZ . LYS B 1 55 ? 162.708 75.703 -105.322 1.00 72.90 ? 63 LYS B NZ 1 ATOM 3923 N N . ASN B 1 56 ? 163.511 79.215 -105.385 1.00 68.48 ? 64 ASN B N 1 ATOM 3924 C CA . ASN B 1 56 ? 162.133 79.713 -105.276 1.00 69.93 ? 64 ASN B CA 1 ATOM 3925 C C . ASN B 1 56 ? 162.101 80.870 -104.268 1.00 69.12 ? 64 ASN B C 1 ATOM 3926 O O . ASN B 1 56 ? 162.227 80.653 -103.058 1.00 69.52 ? 64 ASN B O 1 ATOM 3927 C CB . ASN B 1 56 ? 161.214 78.575 -104.792 1.00 72.59 ? 64 ASN B CB 1 ATOM 3928 C CG . ASN B 1 56 ? 159.744 78.985 -104.694 1.00 74.82 ? 64 ASN B CG 1 ATOM 3929 O OD1 . ASN B 1 56 ? 158.928 78.263 -104.106 1.00 75.20 ? 64 ASN B OD1 1 ATOM 3930 N ND2 . ASN B 1 56 ? 159.399 80.132 -105.277 1.00 75.51 ? 64 ASN B ND2 1 ATOM 3931 N N . GLY B 1 57 ? 161.934 82.095 -104.761 1.00 67.61 ? 65 GLY B N 1 ATOM 3932 C CA . GLY B 1 57 ? 161.907 83.240 -103.868 1.00 65.99 ? 65 GLY B CA 1 ATOM 3933 C C . GLY B 1 57 ? 160.683 83.344 -102.968 1.00 64.92 ? 65 GLY B C 1 ATOM 3934 O O . GLY B 1 57 ? 160.646 84.207 -102.083 1.00 65.91 ? 65 GLY B O 1 ATOM 3935 N N . ARG B 1 58 ? 159.692 82.472 -103.175 1.00 62.77 ? 66 ARG B N 1 ATOM 3936 C CA . ARG B 1 58 ? 158.451 82.491 -102.390 1.00 60.15 ? 66 ARG B CA 1 ATOM 3937 C C . ARG B 1 58 ? 158.701 82.463 -100.889 1.00 57.67 ? 66 ARG B C 1 ATOM 3938 O O . ARG B 1 58 ? 159.135 81.451 -100.335 1.00 57.94 ? 66 ARG B O 1 ATOM 3939 C CB . ARG B 1 58 ? 157.548 81.314 -102.784 1.00 61.89 ? 66 ARG B CB 1 ATOM 3940 C CG . ARG B 1 58 ? 156.176 81.319 -102.103 1.00 64.75 ? 66 ARG B CG 1 ATOM 3941 C CD . ARG B 1 58 ? 155.267 80.200 -102.632 1.00 67.99 ? 66 ARG B CD 1 ATOM 3942 N NE . ARG B 1 58 ? 154.907 80.377 -104.043 1.00 71.92 ? 66 ARG B NE 1 ATOM 3943 C CZ . ARG B 1 58 ? 154.047 81.289 -104.500 1.00 72.34 ? 66 ARG B CZ 1 ATOM 3944 N NH1 . ARG B 1 58 ? 153.441 82.117 -103.659 1.00 72.65 ? 66 ARG B NH1 1 ATOM 3945 N NH2 . ARG B 1 58 ? 153.796 81.382 -105.803 1.00 71.40 ? 66 ARG B NH2 1 ATOM 3946 N N . LYS B 1 59 ? 158.419 83.580 -100.230 1.00 54.33 ? 67 LYS B N 1 ATOM 3947 C CA . LYS B 1 59 ? 158.624 83.678 -98.795 1.00 51.17 ? 67 LYS B CA 1 ATOM 3948 C C . LYS B 1 59 ? 157.419 83.168 -98.020 1.00 49.97 ? 67 LYS B C 1 ATOM 3949 O O . LYS B 1 59 ? 156.283 83.515 -98.327 1.00 50.32 ? 67 LYS B O 1 ATOM 3950 C CB . LYS B 1 59 ? 158.921 85.125 -98.415 1.00 49.90 ? 67 LYS B CB 1 ATOM 3951 C CG . LYS B 1 59 ? 160.182 85.671 -99.063 1.00 48.67 ? 67 LYS B CG 1 ATOM 3952 C CD . LYS B 1 59 ? 160.579 86.980 -98.428 1.00 48.53 ? 67 LYS B CD 1 ATOM 3953 C CE . LYS B 1 59 ? 161.885 87.494 -98.992 1.00 49.50 ? 67 LYS B CE 1 ATOM 3954 N NZ . LYS B 1 59 ? 162.348 88.680 -98.215 1.00 52.44 ? 67 LYS B NZ 1 ATOM 3955 N N . ARG B 1 60 ? 157.676 82.326 -97.024 1.00 48.70 ? 68 ARG B N 1 ATOM 3956 C CA . ARG B 1 60 ? 156.616 81.764 -96.193 1.00 47.01 ? 68 ARG B CA 1 ATOM 3957 C C . ARG B 1 60 ? 156.834 82.145 -94.728 1.00 45.17 ? 68 ARG B C 1 ATOM 3958 O O . ARG B 1 60 ? 157.943 82.511 -94.325 1.00 45.12 ? 68 ARG B O 1 ATOM 3959 C CB . ARG B 1 60 ? 156.587 80.237 -96.326 1.00 49.01 ? 68 ARG B CB 1 ATOM 3960 C CG . ARG B 1 60 ? 156.184 79.730 -97.702 1.00 51.94 ? 68 ARG B CG 1 ATOM 3961 C CD . ARG B 1 60 ? 156.173 78.203 -97.756 1.00 55.28 ? 68 ARG B CD 1 ATOM 3962 N NE . ARG B 1 60 ? 155.927 77.705 -99.110 1.00 59.77 ? 68 ARG B NE 1 ATOM 3963 C CZ . ARG B 1 60 ? 154.756 77.791 -99.743 1.00 63.37 ? 68 ARG B CZ 1 ATOM 3964 N NH1 . ARG B 1 60 ? 153.709 78.353 -99.143 1.00 64.25 ? 68 ARG B NH1 1 ATOM 3965 N NH2 . ARG B 1 60 ? 154.630 77.327 -100.985 1.00 63.73 ? 68 ARG B NH2 1 ATOM 3966 N N . ILE B 1 61 ? 155.773 82.053 -93.933 1.00 42.16 ? 69 ILE B N 1 ATOM 3967 C CA . ILE B 1 61 ? 155.858 82.386 -92.520 1.00 39.45 ? 69 ILE B CA 1 ATOM 3968 C C . ILE B 1 61 ? 155.279 81.285 -91.638 1.00 38.31 ? 69 ILE B C 1 ATOM 3969 O O . ILE B 1 61 ? 154.163 80.818 -91.858 1.00 37.14 ? 69 ILE B O 1 ATOM 3970 C CB . ILE B 1 61 ? 155.129 83.714 -92.226 1.00 38.54 ? 69 ILE B CB 1 ATOM 3971 C CG1 . ILE B 1 61 ? 155.991 84.884 -92.699 1.00 39.37 ? 69 ILE B CG1 1 ATOM 3972 C CG2 . ILE B 1 61 ? 154.834 83.842 -90.746 1.00 38.01 ? 69 ILE B CG2 1 ATOM 3973 C CD1 . ILE B 1 61 ? 155.365 86.239 -92.490 1.00 40.85 ? 69 ILE B CD1 1 ATOM 3974 N N . ALA B 1 62 ? 156.054 80.865 -90.644 1.00 37.16 ? 70 ALA B N 1 ATOM 3975 C CA . ALA B 1 62 ? 155.612 79.833 -89.717 1.00 36.37 ? 70 ALA B CA 1 ATOM 3976 C C . ALA B 1 62 ? 155.548 80.429 -88.315 1.00 36.22 ? 70 ALA B C 1 ATOM 3977 O O . ALA B 1 62 ? 156.439 81.178 -87.914 1.00 35.87 ? 70 ALA B O 1 ATOM 3978 C CB . ALA B 1 62 ? 156.570 78.660 -89.746 1.00 35.06 ? 70 ALA B CB 1 ATOM 3979 N N . LYS B 1 63 ? 154.490 80.107 -87.578 1.00 37.15 ? 71 LYS B N 1 ATOM 3980 C CA . LYS B 1 63 ? 154.323 80.623 -86.223 1.00 38.88 ? 71 LYS B CA 1 ATOM 3981 C C . LYS B 1 63 ? 154.708 79.575 -85.179 1.00 37.38 ? 71 LYS B C 1 ATOM 3982 O O . LYS B 1 63 ? 154.506 78.378 -85.381 1.00 37.87 ? 71 LYS B O 1 ATOM 3983 C CB . LYS B 1 63 ? 152.875 81.085 -86.000 1.00 41.92 ? 71 LYS B CB 1 ATOM 3984 C CG . LYS B 1 63 ? 152.705 82.604 -85.807 1.00 47.73 ? 71 LYS B CG 1 ATOM 3985 C CD . LYS B 1 63 ? 153.326 83.107 -84.477 1.00 52.46 ? 71 LYS B CD 1 ATOM 3986 C CE . LYS B 1 63 ? 153.151 84.638 -84.283 1.00 54.72 ? 71 LYS B CE 1 ATOM 3987 N NZ . LYS B 1 63 ? 153.737 85.164 -82.994 1.00 52.90 ? 71 LYS B NZ 1 ATOM 3988 N N . GLY B 1 64 ? 155.269 80.035 -84.066 1.00 35.46 ? 72 GLY B N 1 ATOM 3989 C CA . GLY B 1 64 ? 155.679 79.128 -83.011 1.00 33.74 ? 72 GLY B CA 1 ATOM 3990 C C . GLY B 1 64 ? 155.142 79.514 -81.644 1.00 33.33 ? 72 GLY B C 1 ATOM 3991 O O . GLY B 1 64 ? 154.223 80.329 -81.539 1.00 32.78 ? 72 GLY B O 1 ATOM 3992 N N . LYS B 1 65 ? 155.711 78.922 -80.596 1.00 32.14 ? 73 LYS B N 1 ATOM 3993 C CA . LYS B 1 65 ? 155.287 79.200 -79.228 1.00 31.49 ? 73 LYS B CA 1 ATOM 3994 C C . LYS B 1 65 ? 156.403 79.926 -78.489 1.00 30.07 ? 73 LYS B C 1 ATOM 3995 O O . LYS B 1 65 ? 157.571 79.832 -78.863 1.00 29.52 ? 73 LYS B O 1 ATOM 3996 C CB . LYS B 1 65 ? 154.971 77.897 -78.474 1.00 32.75 ? 73 LYS B CB 1 ATOM 3997 C CG . LYS B 1 65 ? 153.971 76.965 -79.145 1.00 37.45 ? 73 LYS B CG 1 ATOM 3998 C CD . LYS B 1 65 ? 152.587 77.585 -79.263 1.00 42.82 ? 73 LYS B CD 1 ATOM 3999 C CE . LYS B 1 65 ? 151.655 76.697 -80.100 1.00 46.55 ? 73 LYS B CE 1 ATOM 4000 N NZ . LYS B 1 65 ? 150.272 77.262 -80.276 1.00 47.59 ? 73 LYS B NZ 1 ATOM 4001 N N . MET B 1 66 ? 156.035 80.653 -77.438 1.00 29.19 ? 74 MET B N 1 ATOM 4002 C CA . MET B 1 66 ? 157.007 81.365 -76.620 1.00 28.16 ? 74 MET B CA 1 ATOM 4003 C C . MET B 1 66 ? 156.865 80.892 -75.186 1.00 28.28 ? 74 MET B C 1 ATOM 4004 O O . MET B 1 66 ? 155.775 80.515 -74.750 1.00 27.92 ? 74 MET B O 1 ATOM 4005 C CB . MET B 1 66 ? 156.775 82.868 -76.649 1.00 28.67 ? 74 MET B CB 1 ATOM 4006 C CG . MET B 1 66 ? 157.817 83.623 -75.845 1.00 32.27 ? 74 MET B CG 1 ATOM 4007 S SD . MET B 1 66 ? 157.118 84.652 -74.530 1.00 38.37 ? 74 MET B SD 1 ATOM 4008 C CE . MET B 1 66 ? 156.970 83.512 -73.196 1.00 37.71 ? 74 MET B CE 1 ATOM 4009 N N . SER B 1 67 ? 157.965 80.907 -74.448 1.00 27.14 ? 75 SER B N 1 ATOM 4010 C CA . SER B 1 67 ? 157.920 80.488 -73.062 1.00 26.35 ? 75 SER B CA 1 ATOM 4011 C C . SER B 1 67 ? 158.982 81.189 -72.228 1.00 25.55 ? 75 SER B C 1 ATOM 4012 O O . SER B 1 67 ? 159.879 81.835 -72.761 1.00 25.74 ? 75 SER B O 1 ATOM 4013 C CB . SER B 1 67 ? 158.073 78.968 -72.969 1.00 27.64 ? 75 SER B CB 1 ATOM 4014 O OG . SER B 1 67 ? 159.182 78.507 -73.720 1.00 30.73 ? 75 SER B OG 1 ATOM 4015 N N . THR B 1 68 ? 158.858 81.069 -70.912 1.00 25.19 ? 76 THR B N 1 ATOM 4016 C CA . THR B 1 68 ? 159.799 81.675 -69.978 1.00 23.55 ? 76 THR B CA 1 ATOM 4017 C C . THR B 1 68 ? 159.920 80.756 -68.777 1.00 23.38 ? 76 THR B C 1 ATOM 4018 O O . THR B 1 68 ? 159.140 79.816 -68.629 1.00 24.74 ? 76 THR B O 1 ATOM 4019 C CB . THR B 1 68 ? 159.295 83.039 -69.449 1.00 23.77 ? 76 THR B CB 1 ATOM 4020 O OG1 . THR B 1 68 ? 158.094 82.842 -68.690 1.00 22.29 ? 76 THR B OG1 1 ATOM 4021 C CG2 . THR B 1 68 ? 159.023 84.001 -70.595 1.00 22.47 ? 76 THR B CG2 1 ATOM 4022 N N . TYR B 1 69 ? 160.899 81.021 -67.923 1.00 22.16 ? 77 TYR B N 1 ATOM 4023 C CA . TYR B 1 69 ? 161.064 80.225 -66.719 1.00 21.80 ? 77 TYR B CA 1 ATOM 4024 C C . TYR B 1 69 ? 161.949 80.969 -65.734 1.00 21.94 ? 77 TYR B C 1 ATOM 4025 O O . TYR B 1 69 ? 162.585 81.964 -66.091 1.00 21.08 ? 77 TYR B O 1 ATOM 4026 C CB . TYR B 1 69 ? 161.675 78.861 -67.034 1.00 21.13 ? 77 TYR B CB 1 ATOM 4027 C CG . TYR B 1 69 ? 163.161 78.892 -67.291 1.00 20.85 ? 77 TYR B CG 1 ATOM 4028 C CD1 . TYR B 1 69 ? 163.663 79.274 -68.528 1.00 20.76 ? 77 TYR B CD1 1 ATOM 4029 C CD2 . TYR B 1 69 ? 164.066 78.548 -66.289 1.00 20.56 ? 77 TYR B CD2 1 ATOM 4030 C CE1 . TYR B 1 69 ? 165.030 79.314 -68.765 1.00 23.70 ? 77 TYR B CE1 1 ATOM 4031 C CE2 . TYR B 1 69 ? 165.438 78.586 -66.512 1.00 22.70 ? 77 TYR B CE2 1 ATOM 4032 C CZ . TYR B 1 69 ? 165.914 78.971 -67.754 1.00 25.33 ? 77 TYR B CZ 1 ATOM 4033 O OH . TYR B 1 69 ? 167.276 79.036 -67.985 1.00 26.63 ? 77 TYR B OH 1 ATOM 4034 N N . ARG B 1 70 ? 161.977 80.489 -64.496 1.00 20.94 ? 78 ARG B N 1 ATOM 4035 C CA . ARG B 1 70 ? 162.783 81.101 -63.451 1.00 23.13 ? 78 ARG B CA 1 ATOM 4036 C C . ARG B 1 70 ? 163.558 79.973 -62.803 1.00 24.09 ? 78 ARG B C 1 ATOM 4037 O O . ARG B 1 70 ? 163.035 78.873 -62.656 1.00 24.74 ? 78 ARG B O 1 ATOM 4038 C CB . ARG B 1 70 ? 161.884 81.782 -62.406 1.00 23.61 ? 78 ARG B CB 1 ATOM 4039 C CG . ARG B 1 70 ? 160.904 82.787 -63.001 1.00 29.21 ? 78 ARG B CG 1 ATOM 4040 C CD . ARG B 1 70 ? 159.913 83.340 -61.980 1.00 30.45 ? 78 ARG B CD 1 ATOM 4041 N NE . ARG B 1 70 ? 160.374 84.586 -61.373 1.00 32.88 ? 78 ARG B NE 1 ATOM 4042 C CZ . ARG B 1 70 ? 159.693 85.731 -61.403 1.00 32.30 ? 78 ARG B CZ 1 ATOM 4043 N NH1 . ARG B 1 70 ? 158.515 85.797 -62.013 1.00 32.11 ? 78 ARG B NH1 1 ATOM 4044 N NH2 . ARG B 1 70 ? 160.189 86.812 -60.824 1.00 32.31 ? 78 ARG B NH2 1 ATOM 4045 N N . PHE B 1 71 ? 164.810 80.209 -62.441 1.00 25.64 ? 79 PHE B N 1 ATOM 4046 C CA . PHE B 1 71 ? 165.522 79.140 -61.794 1.00 27.72 ? 79 PHE B CA 1 ATOM 4047 C C . PHE B 1 71 ? 165.488 79.449 -60.312 1.00 30.79 ? 79 PHE B C 1 ATOM 4048 O O . PHE B 1 71 ? 164.586 78.991 -59.603 1.00 35.67 ? 79 PHE B O 1 ATOM 4049 C CB . PHE B 1 71 ? 166.955 79.003 -62.289 1.00 26.83 ? 79 PHE B CB 1 ATOM 4050 C CG . PHE B 1 71 ? 167.560 77.671 -61.951 1.00 24.91 ? 79 PHE B CG 1 ATOM 4051 C CD1 . PHE B 1 71 ? 167.069 76.509 -62.536 1.00 23.73 ? 79 PHE B CD1 1 ATOM 4052 C CD2 . PHE B 1 71 ? 168.559 77.566 -60.989 1.00 23.17 ? 79 PHE B CD2 1 ATOM 4053 C CE1 . PHE B 1 71 ? 167.560 75.256 -62.165 1.00 24.32 ? 79 PHE B CE1 1 ATOM 4054 C CE2 . PHE B 1 71 ? 169.056 76.319 -60.611 1.00 23.96 ? 79 PHE B CE2 1 ATOM 4055 C CZ . PHE B 1 71 ? 168.557 75.163 -61.198 1.00 24.19 ? 79 PHE B CZ 1 ATOM 4056 N N . PHE B 1 72 ? 166.441 80.218 -59.814 1.00 29.95 ? 80 PHE B N 1 ATOM 4057 C CA . PHE B 1 72 ? 166.395 80.533 -58.392 1.00 29.55 ? 80 PHE B CA 1 ATOM 4058 C C . PHE B 1 72 ? 165.928 81.976 -58.372 1.00 29.82 ? 80 PHE B C 1 ATOM 4059 O O . PHE B 1 72 ? 164.732 82.245 -58.487 1.00 29.12 ? 80 PHE B O 1 ATOM 4060 C CB . PHE B 1 72 ? 167.785 80.365 -57.770 1.00 29.24 ? 80 PHE B CB 1 ATOM 4061 C CG . PHE B 1 72 ? 167.850 80.718 -56.316 1.00 28.16 ? 80 PHE B CG 1 ATOM 4062 C CD1 . PHE B 1 72 ? 166.928 80.192 -55.413 1.00 26.85 ? 80 PHE B CD1 1 ATOM 4063 C CD2 . PHE B 1 72 ? 168.846 81.573 -55.847 1.00 27.45 ? 80 PHE B CD2 1 ATOM 4064 C CE1 . PHE B 1 72 ? 166.998 80.516 -54.068 1.00 25.70 ? 80 PHE B CE1 1 ATOM 4065 C CE2 . PHE B 1 72 ? 168.923 81.901 -54.506 1.00 26.25 ? 80 PHE B CE2 1 ATOM 4066 C CZ . PHE B 1 72 ? 167.996 81.370 -53.614 1.00 26.28 ? 80 PHE B CZ 1 ATOM 4067 N N . ASN B 1 73 ? 166.869 82.902 -58.249 1.00 29.70 ? 81 ASN B N 1 ATOM 4068 C CA . ASN B 1 73 ? 166.538 84.312 -58.284 1.00 30.05 ? 81 ASN B CA 1 ATOM 4069 C C . ASN B 1 73 ? 166.794 84.779 -59.719 1.00 29.54 ? 81 ASN B C 1 ATOM 4070 O O . ASN B 1 73 ? 166.898 85.966 -59.988 1.00 30.40 ? 81 ASN B O 1 ATOM 4071 C CB . ASN B 1 73 ? 167.391 85.090 -57.272 1.00 32.36 ? 81 ASN B CB 1 ATOM 4072 C CG . ASN B 1 73 ? 168.878 84.949 -57.519 1.00 35.12 ? 81 ASN B CG 1 ATOM 4073 O OD1 . ASN B 1 73 ? 169.341 83.902 -57.968 1.00 36.90 ? 81 ASN B OD1 1 ATOM 4074 N ND2 . ASN B 1 73 ? 169.629 86.005 -57.208 1.00 38.14 ? 81 ASN B ND2 1 ATOM 4075 N N . TYR B 1 74 ? 166.882 83.822 -60.640 1.00 28.18 ? 82 TYR B N 1 ATOM 4076 C CA . TYR B 1 74 ? 167.117 84.119 -62.054 1.00 27.46 ? 82 TYR B CA 1 ATOM 4077 C C . TYR B 1 74 ? 165.820 84.118 -62.865 1.00 27.74 ? 82 TYR B C 1 ATOM 4078 O O . TYR B 1 74 ? 164.963 83.259 -62.669 1.00 29.06 ? 82 TYR B O 1 ATOM 4079 C CB . TYR B 1 74 ? 168.071 83.086 -62.668 1.00 26.09 ? 82 TYR B CB 1 ATOM 4080 C CG . TYR B 1 74 ? 168.165 83.164 -64.182 1.00 23.02 ? 82 TYR B CG 1 ATOM 4081 C CD1 . TYR B 1 74 ? 169.071 84.027 -64.811 1.00 22.51 ? 82 TYR B CD1 1 ATOM 4082 C CD2 . TYR B 1 74 ? 167.323 82.400 -64.984 1.00 21.40 ? 82 TYR B CD2 1 ATOM 4083 C CE1 . TYR B 1 74 ? 169.132 84.120 -66.199 1.00 20.13 ? 82 TYR B CE1 1 ATOM 4084 C CE2 . TYR B 1 74 ? 167.373 82.486 -66.373 1.00 21.30 ? 82 TYR B CE2 1 ATOM 4085 C CZ . TYR B 1 74 ? 168.279 83.347 -66.975 1.00 22.02 ? 82 TYR B CZ 1 ATOM 4086 O OH . TYR B 1 74 ? 168.334 83.421 -68.354 1.00 19.75 ? 82 TYR B OH 1 ATOM 4087 N N . SER B 1 75 ? 165.681 85.078 -63.775 1.00 27.13 ? 83 SER B N 1 ATOM 4088 C CA . SER B 1 75 ? 164.493 85.165 -64.621 1.00 26.51 ? 83 SER B CA 1 ATOM 4089 C C . SER B 1 75 ? 164.944 85.127 -66.065 1.00 26.30 ? 83 SER B C 1 ATOM 4090 O O . SER B 1 75 ? 165.803 85.904 -66.476 1.00 27.85 ? 83 SER B O 1 ATOM 4091 C CB . SER B 1 75 ? 163.721 86.458 -64.362 1.00 26.37 ? 83 SER B CB 1 ATOM 4092 O OG . SER B 1 75 ? 162.999 86.372 -63.150 1.00 30.52 ? 83 SER B OG 1 ATOM 4093 N N . SER B 1 76 ? 164.361 84.223 -66.840 1.00 24.59 ? 84 SER B N 1 ATOM 4094 C CA . SER B 1 76 ? 164.750 84.079 -68.227 1.00 23.35 ? 84 SER B CA 1 ATOM 4095 C C . SER B 1 76 ? 164.159 85.159 -69.093 1.00 23.54 ? 84 SER B C 1 ATOM 4096 O O . SER B 1 76 ? 163.264 85.889 -68.687 1.00 23.24 ? 84 SER B O 1 ATOM 4097 C CB . SER B 1 76 ? 164.289 82.735 -68.780 1.00 22.74 ? 84 SER B CB 1 ATOM 4098 O OG . SER B 1 76 ? 162.914 82.790 -69.118 1.00 19.48 ? 84 SER B OG 1 ATOM 4099 N N . GLY B 1 77 ? 164.687 85.246 -70.303 1.00 23.67 ? 85 GLY B N 1 ATOM 4100 C CA . GLY B 1 77 ? 164.179 86.196 -71.254 1.00 23.06 ? 85 GLY B CA 1 ATOM 4101 C C . GLY B 1 77 ? 163.053 85.434 -71.911 1.00 24.85 ? 85 GLY B C 1 ATOM 4102 O O . GLY B 1 77 ? 162.544 84.461 -71.354 1.00 25.41 ? 85 GLY B O 1 ATOM 4103 N N . PHE B 1 78 ? 162.685 85.852 -73.109 1.00 24.80 ? 86 PHE B N 1 ATOM 4104 C CA . PHE B 1 78 ? 161.609 85.225 -73.841 1.00 24.02 ? 86 PHE B CA 1 ATOM 4105 C C . PHE B 1 78 ? 162.160 84.234 -74.849 1.00 23.91 ? 86 PHE B C 1 ATOM 4106 O O . PHE B 1 78 ? 162.827 84.599 -75.816 1.00 23.71 ? 86 PHE B O 1 ATOM 4107 C CB . PHE B 1 78 ? 160.787 86.327 -74.498 1.00 25.36 ? 86 PHE B CB 1 ATOM 4108 C CG . PHE B 1 78 ? 160.332 87.371 -73.519 1.00 27.34 ? 86 PHE B CG 1 ATOM 4109 C CD1 . PHE B 1 78 ? 159.238 87.130 -72.686 1.00 27.16 ? 86 PHE B CD1 1 ATOM 4110 C CD2 . PHE B 1 78 ? 161.058 88.555 -73.354 1.00 27.03 ? 86 PHE B CD2 1 ATOM 4111 C CE1 . PHE B 1 78 ? 158.875 88.051 -71.697 1.00 28.13 ? 86 PHE B CE1 1 ATOM 4112 C CE2 . PHE B 1 78 ? 160.708 89.482 -72.371 1.00 26.96 ? 86 PHE B CE2 1 ATOM 4113 C CZ . PHE B 1 78 ? 159.614 89.228 -71.539 1.00 28.25 ? 86 PHE B CZ 1 ATOM 4114 N N . ILE B 1 79 ? 161.882 82.964 -74.591 1.00 24.19 ? 87 ILE B N 1 ATOM 4115 C CA . ILE B 1 79 ? 162.344 81.870 -75.430 1.00 22.70 ? 87 ILE B CA 1 ATOM 4116 C C . ILE B 1 79 ? 161.322 81.529 -76.512 1.00 22.70 ? 87 ILE B C 1 ATOM 4117 O O . ILE B 1 79 ? 160.129 81.369 -76.225 1.00 23.80 ? 87 ILE B O 1 ATOM 4118 C CB . ILE B 1 79 ? 162.620 80.627 -74.553 1.00 20.98 ? 87 ILE B CB 1 ATOM 4119 C CG1 . ILE B 1 79 ? 163.525 81.028 -73.383 1.00 18.94 ? 87 ILE B CG1 1 ATOM 4120 C CG2 . ILE B 1 79 ? 163.277 79.531 -75.376 1.00 20.17 ? 87 ILE B CG2 1 ATOM 4121 C CD1 . ILE B 1 79 ? 163.806 79.912 -72.394 1.00 18.21 ? 87 ILE B CD1 1 ATOM 4122 N N . HIS B 1 80 ? 161.791 81.438 -77.756 1.00 20.78 ? 88 HIS B N 1 ATOM 4123 C CA . HIS B 1 80 ? 160.915 81.110 -78.872 1.00 19.92 ? 88 HIS B CA 1 ATOM 4124 C C . HIS B 1 80 ? 161.334 79.805 -79.552 1.00 20.63 ? 88 HIS B C 1 ATOM 4125 O O . HIS B 1 80 ? 162.528 79.549 -79.752 1.00 18.36 ? 88 HIS B O 1 ATOM 4126 C CB . HIS B 1 80 ? 160.923 82.224 -79.915 1.00 19.71 ? 88 HIS B CB 1 ATOM 4127 C CG . HIS B 1 80 ? 160.484 83.557 -79.391 1.00 19.90 ? 88 HIS B CG 1 ATOM 4128 N ND1 . HIS B 1 80 ? 161.353 84.439 -78.787 1.00 19.32 ? 88 HIS B ND1 1 ATOM 4129 C CD2 . HIS B 1 80 ? 159.271 84.160 -79.388 1.00 18.77 ? 88 HIS B CD2 1 ATOM 4130 C CE1 . HIS B 1 80 ? 160.694 85.530 -78.434 1.00 19.48 ? 88 HIS B CE1 1 ATOM 4131 N NE2 . HIS B 1 80 ? 159.429 85.386 -78.788 1.00 20.35 ? 88 HIS B NE2 1 ATOM 4132 N N . HIS B 1 81 ? 160.340 78.992 -79.906 1.00 19.96 ? 89 HIS B N 1 ATOM 4133 C CA . HIS B 1 81 ? 160.561 77.718 -80.577 1.00 19.99 ? 89 HIS B CA 1 ATOM 4134 C C . HIS B 1 81 ? 159.547 77.626 -81.710 1.00 21.26 ? 89 HIS B C 1 ATOM 4135 O O . HIS B 1 81 ? 158.339 77.672 -81.475 1.00 21.76 ? 89 HIS B O 1 ATOM 4136 C CB . HIS B 1 81 ? 160.355 76.556 -79.601 1.00 19.32 ? 89 HIS B CB 1 ATOM 4137 C CG . HIS B 1 81 ? 161.450 76.406 -78.588 1.00 18.28 ? 89 HIS B CG 1 ATOM 4138 N ND1 . HIS B 1 81 ? 162.728 76.011 -78.925 1.00 17.75 ? 89 HIS B ND1 1 ATOM 4139 C CD2 . HIS B 1 81 ? 161.452 76.579 -77.245 1.00 17.04 ? 89 HIS B CD2 1 ATOM 4140 C CE1 . HIS B 1 81 ? 163.469 75.948 -77.833 1.00 17.28 ? 89 HIS B CE1 1 ATOM 4141 N NE2 . HIS B 1 81 ? 162.719 76.287 -76.800 1.00 17.92 ? 89 HIS B NE2 1 ATOM 4142 N N . THR B 1 82 ? 160.040 77.498 -82.937 1.00 22.36 ? 90 THR B N 1 ATOM 4143 C CA . THR B 1 82 ? 159.172 77.411 -84.103 1.00 24.25 ? 90 THR B CA 1 ATOM 4144 C C . THR B 1 82 ? 159.600 76.264 -84.996 1.00 26.29 ? 90 THR B C 1 ATOM 4145 O O . THR B 1 82 ? 160.785 76.091 -85.267 1.00 28.18 ? 90 THR B O 1 ATOM 4146 C CB . THR B 1 82 ? 159.219 78.717 -84.938 1.00 24.14 ? 90 THR B CB 1 ATOM 4147 O OG1 . THR B 1 82 ? 158.680 79.797 -84.167 1.00 22.35 ? 90 THR B OG1 1 ATOM 4148 C CG2 . THR B 1 82 ? 158.417 78.568 -86.227 1.00 21.03 ? 90 THR B CG2 1 ATOM 4149 N N . THR B 1 83 ? 158.634 75.492 -85.472 1.00 27.50 ? 91 THR B N 1 ATOM 4150 C CA . THR B 1 83 ? 158.945 74.368 -86.338 1.00 28.80 ? 91 THR B CA 1 ATOM 4151 C C . THR B 1 83 ? 158.525 74.598 -87.787 1.00 30.71 ? 91 THR B C 1 ATOM 4152 O O . THR B 1 83 ? 157.343 74.776 -88.088 1.00 31.26 ? 91 THR B O 1 ATOM 4153 C CB . THR B 1 83 ? 158.289 73.082 -85.807 1.00 28.00 ? 91 THR B CB 1 ATOM 4154 O OG1 . THR B 1 83 ? 158.829 72.785 -84.513 1.00 27.92 ? 91 THR B OG1 1 ATOM 4155 C CG2 . THR B 1 83 ? 158.550 71.914 -86.740 1.00 26.35 ? 91 THR B CG2 1 ATOM 4156 N N . ILE B 1 84 ? 159.521 74.612 -88.670 1.00 32.59 ? 92 ILE B N 1 ATOM 4157 C CA . ILE B 1 84 ? 159.328 74.788 -90.106 1.00 33.87 ? 92 ILE B CA 1 ATOM 4158 C C . ILE B 1 84 ? 159.276 73.385 -90.696 1.00 35.37 ? 92 ILE B C 1 ATOM 4159 O O . ILE B 1 84 ? 160.242 72.628 -90.584 1.00 35.62 ? 92 ILE B O 1 ATOM 4160 C CB . ILE B 1 84 ? 160.526 75.493 -90.752 1.00 33.88 ? 92 ILE B CB 1 ATOM 4161 C CG1 . ILE B 1 84 ? 160.746 76.865 -90.126 1.00 33.46 ? 92 ILE B CG1 1 ATOM 4162 C CG2 . ILE B 1 84 ? 160.300 75.625 -92.239 1.00 35.79 ? 92 ILE B CG2 1 ATOM 4163 C CD1 . ILE B 1 84 ? 161.936 77.599 -90.723 1.00 32.14 ? 92 ILE B CD1 1 ATOM 4164 N N . ARG B 1 85 ? 158.166 73.031 -91.328 1.00 36.81 ? 93 ARG B N 1 ATOM 4165 C CA . ARG B 1 85 ? 158.051 71.700 -91.899 1.00 39.76 ? 93 ARG B CA 1 ATOM 4166 C C . ARG B 1 85 ? 157.854 71.692 -93.419 1.00 40.07 ? 93 ARG B C 1 ATOM 4167 O O . ARG B 1 85 ? 157.849 72.743 -94.063 1.00 40.39 ? 93 ARG B O 1 ATOM 4168 C CB . ARG B 1 85 ? 156.919 70.952 -91.195 1.00 41.64 ? 93 ARG B CB 1 ATOM 4169 C CG . ARG B 1 85 ? 155.709 71.815 -90.943 1.00 48.32 ? 93 ARG B CG 1 ATOM 4170 C CD . ARG B 1 85 ? 154.617 71.104 -90.149 1.00 53.90 ? 93 ARG B CD 1 ATOM 4171 N NE . ARG B 1 85 ? 154.957 70.892 -88.740 1.00 58.05 ? 93 ARG B NE 1 ATOM 4172 C CZ . ARG B 1 85 ? 155.623 69.836 -88.273 1.00 60.60 ? 93 ARG B CZ 1 ATOM 4173 N NH1 . ARG B 1 85 ? 156.030 68.877 -89.102 1.00 60.37 ? 93 ARG B NH1 1 ATOM 4174 N NH2 . ARG B 1 85 ? 155.873 69.730 -86.970 1.00 60.36 ? 93 ARG B NH2 1 ATOM 4175 N N . LYS B 1 86 ? 157.712 70.496 -93.986 1.00 40.08 ? 94 LYS B N 1 ATOM 4176 C CA . LYS B 1 86 ? 157.520 70.324 -95.425 1.00 38.89 ? 94 LYS B CA 1 ATOM 4177 C C . LYS B 1 86 ? 158.572 71.007 -96.302 1.00 37.22 ? 94 LYS B C 1 ATOM 4178 O O . LYS B 1 86 ? 158.260 71.491 -97.388 1.00 38.01 ? 94 LYS B O 1 ATOM 4179 C CB . LYS B 1 86 ? 156.114 70.791 -95.838 1.00 40.25 ? 94 LYS B CB 1 ATOM 4180 C CG . LYS B 1 86 ? 155.002 69.802 -95.479 1.00 43.64 ? 94 LYS B CG 1 ATOM 4181 C CD . LYS B 1 86 ? 153.633 70.213 -96.045 1.00 47.87 ? 94 LYS B CD 1 ATOM 4182 C CE . LYS B 1 86 ? 153.078 71.479 -95.378 1.00 50.58 ? 94 LYS B CE 1 ATOM 4183 N NZ . LYS B 1 86 ? 152.853 71.316 -93.901 1.00 52.72 ? 94 LYS B NZ 1 ATOM 4184 N N . LEU B 1 87 ? 159.817 71.038 -95.840 1.00 34.79 ? 95 LEU B N 1 ATOM 4185 C CA . LEU B 1 87 ? 160.895 71.646 -96.615 1.00 32.67 ? 95 LEU B CA 1 ATOM 4186 C C . LEU B 1 87 ? 161.329 70.693 -97.725 1.00 32.67 ? 95 LEU B C 1 ATOM 4187 O O . LEU B 1 87 ? 160.880 69.548 -97.783 1.00 32.93 ? 95 LEU B O 1 ATOM 4188 C CB . LEU B 1 87 ? 162.093 71.959 -95.715 1.00 31.44 ? 95 LEU B CB 1 ATOM 4189 C CG . LEU B 1 87 ? 161.858 72.975 -94.593 1.00 31.68 ? 95 LEU B CG 1 ATOM 4190 C CD1 . LEU B 1 87 ? 163.048 72.989 -93.650 1.00 30.39 ? 95 LEU B CD1 1 ATOM 4191 C CD2 . LEU B 1 87 ? 161.623 74.357 -95.190 1.00 30.45 ? 95 LEU B CD2 1 ATOM 4192 N N . LYS B 1 88 ? 162.193 71.170 -98.615 1.00 32.70 ? 96 LYS B N 1 ATOM 4193 C CA . LYS B 1 88 ? 162.686 70.345 -99.714 1.00 33.73 ? 96 LYS B CA 1 ATOM 4194 C C . LYS B 1 88 ? 164.074 69.829 -99.367 1.00 32.54 ? 96 LYS B C 1 ATOM 4195 O O . LYS B 1 88 ? 164.851 70.523 -98.708 1.00 31.80 ? 96 LYS B O 1 ATOM 4196 C CB . LYS B 1 88 ? 162.772 71.158 -101.007 1.00 36.82 ? 96 LYS B CB 1 ATOM 4197 C CG . LYS B 1 88 ? 161.442 71.521 -101.638 1.00 42.03 ? 96 LYS B CG 1 ATOM 4198 C CD . LYS B 1 88 ? 161.650 72.458 -102.831 1.00 47.94 ? 96 LYS B CD 1 ATOM 4199 C CE . LYS B 1 88 ? 162.586 71.845 -103.883 1.00 51.23 ? 96 LYS B CE 1 ATOM 4200 N NZ . LYS B 1 88 ? 162.778 72.723 -105.081 1.00 52.36 ? 96 LYS B NZ 1 ATOM 4201 N N . TYR B 1 89 ? 164.384 68.617 -99.816 1.00 30.99 ? 97 TYR B N 1 ATOM 4202 C CA . TYR B 1 89 ? 165.685 68.019 -99.551 1.00 30.29 ? 97 TYR B CA 1 ATOM 4203 C C . TYR B 1 89 ? 166.820 68.737 -100.252 1.00 29.79 ? 97 TYR B C 1 ATOM 4204 O O . TYR B 1 89 ? 166.624 69.466 -101.220 1.00 28.04 ? 97 TYR B O 1 ATOM 4205 C CB . TYR B 1 89 ? 165.697 66.556 -99.971 1.00 30.46 ? 97 TYR B CB 1 ATOM 4206 C CG . TYR B 1 89 ? 164.921 65.650 -99.055 1.00 32.72 ? 97 TYR B CG 1 ATOM 4207 C CD1 . TYR B 1 89 ? 165.411 65.330 -97.791 1.00 34.29 ? 97 TYR B CD1 1 ATOM 4208 C CD2 . TYR B 1 89 ? 163.710 65.083 -99.462 1.00 33.29 ? 97 TYR B CD2 1 ATOM 4209 C CE1 . TYR B 1 89 ? 164.718 64.458 -96.952 1.00 36.21 ? 97 TYR B CE1 1 ATOM 4210 C CE2 . TYR B 1 89 ? 163.008 64.212 -98.633 1.00 35.34 ? 97 TYR B CE2 1 ATOM 4211 C CZ . TYR B 1 89 ? 163.519 63.902 -97.382 1.00 37.00 ? 97 TYR B CZ 1 ATOM 4212 O OH . TYR B 1 89 ? 162.843 63.018 -96.576 1.00 40.79 ? 97 TYR B OH 1 ATOM 4213 N N . ASN B 1 90 ? 168.017 68.506 -99.741 1.00 31.88 ? 98 ASN B N 1 ATOM 4214 C CA . ASN B 1 90 ? 169.239 69.092 -100.269 1.00 33.65 ? 98 ASN B CA 1 ATOM 4215 C C . ASN B 1 90 ? 169.081 70.450 -100.955 1.00 33.49 ? 98 ASN B C 1 ATOM 4216 O O . ASN B 1 90 ? 169.457 70.621 -102.118 1.00 32.62 ? 98 ASN B O 1 ATOM 4217 C CB . ASN B 1 90 ? 169.916 68.098 -101.215 1.00 35.75 ? 98 ASN B CB 1 ATOM 4218 C CG . ASN B 1 90 ? 171.289 68.562 -101.656 1.00 39.60 ? 98 ASN B CG 1 ATOM 4219 O OD1 . ASN B 1 90 ? 172.127 68.947 -100.833 1.00 40.76 ? 98 ASN B OD1 1 ATOM 4220 N ND2 . ASN B 1 90 ? 171.532 68.525 -102.961 1.00 42.30 ? 98 ASN B ND2 1 ATOM 4221 N N . THR B 1 91 ? 168.532 71.417 -100.222 1.00 33.88 ? 99 THR B N 1 ATOM 4222 C CA . THR B 1 91 ? 168.346 72.773 -100.737 1.00 34.44 ? 99 THR B CA 1 ATOM 4223 C C . THR B 1 91 ? 168.597 73.833 -99.660 1.00 34.71 ? 99 THR B C 1 ATOM 4224 O O . THR B 1 91 ? 168.230 73.656 -98.493 1.00 34.81 ? 99 THR B O 1 ATOM 4225 C CB . THR B 1 91 ? 166.922 72.976 -101.349 1.00 34.99 ? 99 THR B CB 1 ATOM 4226 O OG1 . THR B 1 91 ? 166.509 74.341 -101.180 1.00 35.62 ? 99 THR B OG1 1 ATOM 4227 C CG2 . THR B 1 91 ? 165.916 72.062 -100.705 1.00 35.25 ? 99 THR B CG2 1 ATOM 4228 N N . LYS B 1 92 ? 169.239 74.929 -100.061 1.00 33.95 ? 100 LYS B N 1 ATOM 4229 C CA . LYS B 1 92 ? 169.555 76.023 -99.150 1.00 33.27 ? 100 LYS B CA 1 ATOM 4230 C C . LYS B 1 92 ? 168.320 76.879 -98.889 1.00 33.33 ? 100 LYS B C 1 ATOM 4231 O O . LYS B 1 92 ? 167.557 77.186 -99.807 1.00 33.56 ? 100 LYS B O 1 ATOM 4232 C CB . LYS B 1 92 ? 170.678 76.897 -99.730 1.00 33.55 ? 100 LYS B CB 1 ATOM 4233 C CG . LYS B 1 92 ? 171.242 77.925 -98.751 1.00 33.74 ? 100 LYS B CG 1 ATOM 4234 C CD . LYS B 1 92 ? 172.401 78.695 -99.359 1.00 35.76 ? 100 LYS B CD 1 ATOM 4235 C CE . LYS B 1 92 ? 172.959 79.717 -98.385 1.00 38.05 ? 100 LYS B CE 1 ATOM 4236 N NZ . LYS B 1 92 ? 174.061 80.522 -98.985 1.00 40.22 ? 100 LYS B NZ 1 ATOM 4237 N N . TYR B 1 93 ? 168.134 77.249 -97.625 1.00 32.71 ? 101 TYR B N 1 ATOM 4238 C CA . TYR B 1 93 ? 167.010 78.069 -97.191 1.00 31.02 ? 101 TYR B CA 1 ATOM 4239 C C . TYR B 1 93 ? 167.512 79.241 -96.369 1.00 30.76 ? 101 TYR B C 1 ATOM 4240 O O . TYR B 1 93 ? 168.517 79.134 -95.666 1.00 30.19 ? 101 TYR B O 1 ATOM 4241 C CB . TYR B 1 93 ? 166.066 77.254 -96.309 1.00 29.88 ? 101 TYR B CB 1 ATOM 4242 C CG . TYR B 1 93 ? 165.069 76.395 -97.048 1.00 30.47 ? 101 TYR B CG 1 ATOM 4243 C CD1 . TYR B 1 93 ? 163.845 76.917 -97.451 1.00 29.50 ? 101 TYR B CD1 1 ATOM 4244 C CD2 . TYR B 1 93 ? 165.341 75.054 -97.330 1.00 31.06 ? 101 TYR B CD2 1 ATOM 4245 C CE1 . TYR B 1 93 ? 162.916 76.133 -98.111 1.00 30.26 ? 101 TYR B CE1 1 ATOM 4246 C CE2 . TYR B 1 93 ? 164.418 74.258 -97.993 1.00 30.38 ? 101 TYR B CE2 1 ATOM 4247 C CZ . TYR B 1 93 ? 163.207 74.803 -98.381 1.00 31.37 ? 101 TYR B CZ 1 ATOM 4248 O OH . TYR B 1 93 ? 162.290 74.023 -99.054 1.00 34.06 ? 101 TYR B OH 1 ATOM 4249 N N . TYR B 1 94 ? 166.813 80.364 -96.469 1.00 31.24 ? 102 TYR B N 1 ATOM 4250 C CA . TYR B 1 94 ? 167.149 81.539 -95.677 1.00 30.96 ? 102 TYR B CA 1 ATOM 4251 C C . TYR B 1 94 ? 165.995 81.696 -94.708 1.00 30.50 ? 102 TYR B C 1 ATOM 4252 O O . TYR B 1 94 ? 164.851 81.382 -95.048 1.00 28.97 ? 102 TYR B O 1 ATOM 4253 C CB . TYR B 1 94 ? 167.249 82.801 -96.539 1.00 32.22 ? 102 TYR B CB 1 ATOM 4254 C CG . TYR B 1 94 ? 168.495 82.857 -97.372 1.00 37.05 ? 102 TYR B CG 1 ATOM 4255 C CD1 . TYR B 1 94 ? 168.529 82.302 -98.655 1.00 38.42 ? 102 TYR B CD1 1 ATOM 4256 C CD2 . TYR B 1 94 ? 169.673 83.391 -96.849 1.00 38.72 ? 102 TYR B CD2 1 ATOM 4257 C CE1 . TYR B 1 94 ? 169.714 82.268 -99.393 1.00 40.11 ? 102 TYR B CE1 1 ATOM 4258 C CE2 . TYR B 1 94 ? 170.865 83.362 -97.576 1.00 40.41 ? 102 TYR B CE2 1 ATOM 4259 C CZ . TYR B 1 94 ? 170.879 82.795 -98.843 1.00 40.80 ? 102 TYR B CZ 1 ATOM 4260 O OH . TYR B 1 94 ? 172.063 82.708 -99.536 1.00 43.33 ? 102 TYR B OH 1 ATOM 4261 N N . TYR B 1 95 ? 166.288 82.141 -93.492 1.00 30.55 ? 103 TYR B N 1 ATOM 4262 C CA . TYR B 1 95 ? 165.225 82.369 -92.527 1.00 30.45 ? 103 TYR B CA 1 ATOM 4263 C C . TYR B 1 95 ? 165.548 83.586 -91.692 1.00 32.00 ? 103 TYR B C 1 ATOM 4264 O O . TYR B 1 95 ? 166.689 83.778 -91.256 1.00 32.46 ? 103 TYR B O 1 ATOM 4265 C CB . TYR B 1 95 ? 164.988 81.150 -91.626 1.00 29.01 ? 103 TYR B CB 1 ATOM 4266 C CG . TYR B 1 95 ? 166.068 80.851 -90.616 1.00 27.43 ? 103 TYR B CG 1 ATOM 4267 C CD1 . TYR B 1 95 ? 167.181 80.084 -90.958 1.00 26.99 ? 103 TYR B CD1 1 ATOM 4268 C CD2 . TYR B 1 95 ? 165.963 81.313 -89.305 1.00 27.18 ? 103 TYR B CD2 1 ATOM 4269 C CE1 . TYR B 1 95 ? 168.165 79.779 -90.017 1.00 26.74 ? 103 TYR B CE1 1 ATOM 4270 C CE2 . TYR B 1 95 ? 166.943 81.018 -88.352 1.00 27.21 ? 103 TYR B CE2 1 ATOM 4271 C CZ . TYR B 1 95 ? 168.041 80.250 -88.714 1.00 27.36 ? 103 TYR B CZ 1 ATOM 4272 O OH . TYR B 1 95 ? 169.013 79.962 -87.774 1.00 25.30 ? 103 TYR B OH 1 ATOM 4273 N N . GLU B 1 96 ? 164.540 84.429 -91.507 1.00 32.96 ? 104 GLU B N 1 ATOM 4274 C CA . GLU B 1 96 ? 164.697 85.640 -90.724 1.00 34.31 ? 104 GLU B CA 1 ATOM 4275 C C . GLU B 1 96 ? 163.881 85.496 -89.468 1.00 34.44 ? 104 GLU B C 1 ATOM 4276 O O . GLU B 1 96 ? 162.834 84.832 -89.453 1.00 34.18 ? 104 GLU B O 1 ATOM 4277 C CB . GLU B 1 96 ? 164.232 86.864 -91.505 1.00 36.86 ? 104 GLU B CB 1 ATOM 4278 C CG . GLU B 1 96 ? 165.161 87.251 -92.631 1.00 40.39 ? 104 GLU B CG 1 ATOM 4279 C CD . GLU B 1 96 ? 164.716 88.512 -93.310 1.00 41.86 ? 104 GLU B CD 1 ATOM 4280 O OE1 . GLU B 1 96 ? 163.554 88.542 -93.775 1.00 42.85 ? 104 GLU B OE1 1 ATOM 4281 O OE2 . GLU B 1 96 ? 165.528 89.462 -93.368 1.00 43.67 ? 104 GLU B OE2 1 ATOM 4282 N N . VAL B 1 97 ? 164.354 86.140 -88.412 1.00 33.16 ? 105 VAL B N 1 ATOM 4283 C CA . VAL B 1 97 ? 163.684 86.032 -87.144 1.00 31.35 ? 105 VAL B CA 1 ATOM 4284 C C . VAL B 1 97 ? 163.725 87.374 -86.403 1.00 32.10 ? 105 VAL B C 1 ATOM 4285 O O . VAL B 1 97 ? 164.656 88.165 -86.575 1.00 31.50 ? 105 VAL B O 1 ATOM 4286 C CB . VAL B 1 97 ? 164.349 84.880 -86.354 1.00 29.38 ? 105 VAL B CB 1 ATOM 4287 C CG1 . VAL B 1 97 ? 165.610 85.354 -85.677 1.00 28.07 ? 105 VAL B CG1 1 ATOM 4288 C CG2 . VAL B 1 97 ? 163.373 84.278 -85.412 1.00 30.34 ? 105 VAL B CG2 1 ATOM 4289 N N . GLY B 1 98 ? 162.701 87.630 -85.593 1.00 33.08 ? 106 GLY B N 1 ATOM 4290 C CA . GLY B 1 98 ? 162.618 88.885 -84.865 1.00 32.92 ? 106 GLY B CA 1 ATOM 4291 C C . GLY B 1 98 ? 161.922 89.893 -85.756 1.00 33.27 ? 106 GLY B C 1 ATOM 4292 O O . GLY B 1 98 ? 162.221 91.080 -85.736 1.00 33.24 ? 106 GLY B O 1 ATOM 4293 N N . LEU B 1 99 ? 160.972 89.401 -86.541 1.00 34.38 ? 107 LEU B N 1 ATOM 4294 C CA . LEU B 1 99 ? 160.230 90.222 -87.492 1.00 35.52 ? 107 LEU B CA 1 ATOM 4295 C C . LEU B 1 99 ? 159.698 91.549 -86.976 1.00 37.28 ? 107 LEU B C 1 ATOM 4296 O O . LEU B 1 99 ? 160.021 92.610 -87.509 1.00 40.30 ? 107 LEU B O 1 ATOM 4297 C CB . LEU B 1 99 ? 159.064 89.419 -88.070 1.00 33.11 ? 107 LEU B CB 1 ATOM 4298 C CG . LEU B 1 99 ? 159.401 88.039 -88.629 1.00 31.48 ? 107 LEU B CG 1 ATOM 4299 C CD1 . LEU B 1 99 ? 158.188 87.490 -89.353 1.00 31.57 ? 107 LEU B CD1 1 ATOM 4300 C CD2 . LEU B 1 99 ? 160.578 88.136 -89.577 1.00 30.58 ? 107 LEU B CD2 1 ATOM 4301 N N . ARG B 1 100 ? 158.868 91.492 -85.949 1.00 38.39 ? 108 ARG B N 1 ATOM 4302 C CA . ARG B 1 100 ? 158.268 92.703 -85.409 1.00 40.62 ? 108 ARG B CA 1 ATOM 4303 C C . ARG B 1 100 ? 159.244 93.870 -85.157 1.00 40.22 ? 108 ARG B C 1 ATOM 4304 O O . ARG B 1 100 ? 158.943 95.026 -85.489 1.00 37.50 ? 108 ARG B O 1 ATOM 4305 C CB . ARG B 1 100 ? 157.493 92.360 -84.107 1.00 40.82 ? 108 ARG B CB 1 ATOM 4306 N N . ASN B 1 101 ? 160.411 93.558 -84.593 1.00 40.63 ? 109 ASN B N 1 ATOM 4307 C CA . ASN B 1 101 ? 161.407 94.575 -84.232 1.00 41.49 ? 109 ASN B CA 1 ATOM 4308 C C . ASN B 1 101 ? 162.722 94.500 -85.018 1.00 40.05 ? 109 ASN B C 1 ATOM 4309 O O . ASN B 1 101 ? 162.715 94.649 -86.233 1.00 42.14 ? 109 ASN B O 1 ATOM 4310 C CB . ASN B 1 101 ? 161.676 94.462 -82.729 1.00 45.97 ? 109 ASN B CB 1 ATOM 4311 C CG . ASN B 1 101 ? 160.401 94.201 -81.936 1.00 50.80 ? 109 ASN B CG 1 ATOM 4312 O OD1 . ASN B 1 101 ? 160.384 93.410 -80.988 1.00 49.05 ? 109 ASN B OD1 1 ATOM 4313 N ND2 . ASN B 1 101 ? 159.331 94.874 -82.346 1.00 56.38 ? 109 ASN B ND2 1 ATOM 4314 N N . THR B 1 102 ? 163.848 94.292 -84.334 1.00 36.80 ? 110 THR B N 1 ATOM 4315 C CA . THR B 1 102 ? 165.145 94.192 -85.018 1.00 34.15 ? 110 THR B CA 1 ATOM 4316 C C . THR B 1 102 ? 165.287 92.806 -85.649 1.00 33.87 ? 110 THR B C 1 ATOM 4317 O O . THR B 1 102 ? 165.320 91.805 -84.945 1.00 34.62 ? 110 THR B O 1 ATOM 4318 C CB . THR B 1 102 ? 166.338 94.397 -84.049 1.00 33.12 ? 110 THR B CB 1 ATOM 4319 O OG1 . THR B 1 102 ? 166.344 95.743 -83.555 1.00 32.10 ? 110 THR B OG1 1 ATOM 4320 C CG2 . THR B 1 102 ? 167.652 94.116 -84.760 1.00 30.46 ? 110 THR B CG2 1 ATOM 4321 N N . THR B 1 103 ? 165.389 92.754 -86.974 1.00 33.65 ? 111 THR B N 1 ATOM 4322 C CA . THR B 1 103 ? 165.500 91.489 -87.699 1.00 33.37 ? 111 THR B CA 1 ATOM 4323 C C . THR B 1 103 ? 166.922 91.018 -87.989 1.00 32.84 ? 111 THR B C 1 ATOM 4324 O O . THR B 1 103 ? 167.785 91.820 -88.348 1.00 34.08 ? 111 THR B O 1 ATOM 4325 C CB . THR B 1 103 ? 164.771 91.575 -89.051 1.00 33.79 ? 111 THR B CB 1 ATOM 4326 O OG1 . THR B 1 103 ? 163.392 91.893 -88.831 1.00 37.04 ? 111 THR B OG1 1 ATOM 4327 C CG2 . THR B 1 103 ? 164.863 90.254 -89.789 1.00 34.42 ? 111 THR B CG2 1 ATOM 4328 N N . ARG B 1 104 ? 167.152 89.712 -87.829 1.00 31.93 ? 112 ARG B N 1 ATOM 4329 C CA . ARG B 1 104 ? 168.453 89.089 -88.119 1.00 30.82 ? 112 ARG B CA 1 ATOM 4330 C C . ARG B 1 104 ? 168.199 87.914 -89.069 1.00 31.22 ? 112 ARG B C 1 ATOM 4331 O O . ARG B 1 104 ? 167.169 87.241 -88.964 1.00 32.05 ? 112 ARG B O 1 ATOM 4332 C CB . ARG B 1 104 ? 169.136 88.584 -86.847 1.00 27.83 ? 112 ARG B CB 1 ATOM 4333 C CG . ARG B 1 104 ? 169.567 89.675 -85.887 1.00 27.29 ? 112 ARG B CG 1 ATOM 4334 C CD . ARG B 1 104 ? 170.287 89.080 -84.689 1.00 27.99 ? 112 ARG B CD 1 ATOM 4335 N NE . ARG B 1 104 ? 171.509 88.393 -85.092 1.00 28.39 ? 112 ARG B NE 1 ATOM 4336 C CZ . ARG B 1 104 ? 172.150 87.498 -84.349 1.00 30.01 ? 112 ARG B CZ 1 ATOM 4337 N NH1 . ARG B 1 104 ? 171.689 87.165 -83.149 1.00 30.83 ? 112 ARG B NH1 1 ATOM 4338 N NH2 . ARG B 1 104 ? 173.255 86.929 -84.809 1.00 30.17 ? 112 ARG B NH2 1 ATOM 4339 N N . ARG B 1 105 ? 169.125 87.668 -89.993 1.00 31.36 ? 113 ARG B N 1 ATOM 4340 C CA . ARG B 1 105 ? 168.952 86.593 -90.965 1.00 30.90 ? 113 ARG B CA 1 ATOM 4341 C C . ARG B 1 105 ? 170.051 85.530 -90.944 1.00 30.52 ? 113 ARG B C 1 ATOM 4342 O O . ARG B 1 105 ? 171.236 85.840 -90.771 1.00 29.46 ? 113 ARG B O 1 ATOM 4343 C CB . ARG B 1 105 ? 168.861 87.192 -92.364 1.00 32.35 ? 113 ARG B CB 1 ATOM 4344 C CG . ARG B 1 105 ? 168.792 86.166 -93.474 1.00 36.02 ? 113 ARG B CG 1 ATOM 4345 C CD . ARG B 1 105 ? 168.870 86.838 -94.826 1.00 39.49 ? 113 ARG B CD 1 ATOM 4346 N NE . ARG B 1 105 ? 167.816 87.833 -94.996 1.00 43.89 ? 113 ARG B NE 1 ATOM 4347 C CZ . ARG B 1 105 ? 167.642 88.543 -96.106 1.00 45.96 ? 113 ARG B CZ 1 ATOM 4348 N NH1 . ARG B 1 105 ? 168.456 88.361 -97.136 1.00 47.50 ? 113 ARG B NH1 1 ATOM 4349 N NH2 . ARG B 1 105 ? 166.657 89.430 -96.189 1.00 46.57 ? 113 ARG B NH2 1 ATOM 4350 N N . PHE B 1 106 ? 169.642 84.276 -91.126 1.00 29.55 ? 114 PHE B N 1 ATOM 4351 C CA . PHE B 1 106 ? 170.570 83.146 -91.151 1.00 29.05 ? 114 PHE B CA 1 ATOM 4352 C C . PHE B 1 106 ? 170.163 82.208 -92.287 1.00 29.79 ? 114 PHE B C 1 ATOM 4353 O O . PHE B 1 106 ? 169.197 82.482 -93.009 1.00 29.06 ? 114 PHE B O 1 ATOM 4354 C CB . PHE B 1 106 ? 170.537 82.382 -89.819 1.00 26.40 ? 114 PHE B CB 1 ATOM 4355 C CG . PHE B 1 106 ? 170.747 83.251 -88.618 1.00 26.78 ? 114 PHE B CG 1 ATOM 4356 C CD1 . PHE B 1 106 ? 169.683 83.977 -88.066 1.00 25.70 ? 114 PHE B CD1 1 ATOM 4357 C CD2 . PHE B 1 106 ? 172.012 83.371 -88.045 1.00 27.06 ? 114 PHE B CD2 1 ATOM 4358 C CE1 . PHE B 1 106 ? 169.876 84.811 -86.955 1.00 25.01 ? 114 PHE B CE1 1 ATOM 4359 C CE2 . PHE B 1 106 ? 172.219 84.208 -86.927 1.00 27.31 ? 114 PHE B CE2 1 ATOM 4360 C CZ . PHE B 1 106 ? 171.146 84.926 -86.386 1.00 25.97 ? 114 PHE B CZ 1 ATOM 4361 N N . SER B 1 107 ? 170.898 81.110 -92.448 1.00 29.34 ? 115 SER B N 1 ATOM 4362 C CA . SER B 1 107 ? 170.583 80.148 -93.494 1.00 30.09 ? 115 SER B CA 1 ATOM 4363 C C . SER B 1 107 ? 171.017 78.753 -93.078 1.00 30.22 ? 115 SER B C 1 ATOM 4364 O O . SER B 1 107 ? 171.856 78.590 -92.198 1.00 30.89 ? 115 SER B O 1 ATOM 4365 C CB . SER B 1 107 ? 171.288 80.518 -94.805 1.00 29.29 ? 115 SER B CB 1 ATOM 4366 O OG . SER B 1 107 ? 172.692 80.345 -94.699 1.00 28.55 ? 115 SER B OG 1 ATOM 4367 N N . PHE B 1 108 ? 170.436 77.750 -93.720 1.00 29.92 ? 116 PHE B N 1 ATOM 4368 C CA . PHE B 1 108 ? 170.782 76.368 -93.441 1.00 29.97 ? 116 PHE B CA 1 ATOM 4369 C C . PHE B 1 108 ? 170.511 75.556 -94.699 1.00 30.14 ? 116 PHE B C 1 ATOM 4370 O O . PHE B 1 108 ? 169.757 75.994 -95.570 1.00 30.47 ? 116 PHE B O 1 ATOM 4371 C CB . PHE B 1 108 ? 169.966 75.841 -92.257 1.00 28.51 ? 116 PHE B CB 1 ATOM 4372 C CG . PHE B 1 108 ? 168.490 75.776 -92.510 1.00 27.25 ? 116 PHE B CG 1 ATOM 4373 C CD1 . PHE B 1 108 ? 167.949 74.790 -93.332 1.00 26.74 ? 116 PHE B CD1 1 ATOM 4374 C CD2 . PHE B 1 108 ? 167.633 76.693 -91.909 1.00 26.95 ? 116 PHE B CD2 1 ATOM 4375 C CE1 . PHE B 1 108 ? 166.571 74.717 -93.551 1.00 27.06 ? 116 PHE B CE1 1 ATOM 4376 C CE2 . PHE B 1 108 ? 166.255 76.631 -92.119 1.00 26.09 ? 116 PHE B CE2 1 ATOM 4377 C CZ . PHE B 1 108 ? 165.723 75.640 -92.942 1.00 26.73 ? 116 PHE B CZ 1 ATOM 4378 N N . ILE B 1 109 ? 171.129 74.385 -94.805 1.00 29.43 ? 117 ILE B N 1 ATOM 4379 C CA . ILE B 1 109 ? 170.929 73.548 -95.979 1.00 29.02 ? 117 ILE B CA 1 ATOM 4380 C C . ILE B 1 109 ? 170.348 72.191 -95.596 1.00 28.93 ? 117 ILE B C 1 ATOM 4381 O O . ILE B 1 109 ? 171.014 71.387 -94.937 1.00 29.59 ? 117 ILE B O 1 ATOM 4382 C CB . ILE B 1 109 ? 172.247 73.325 -96.712 1.00 28.56 ? 117 ILE B CB 1 ATOM 4383 C CG1 . ILE B 1 109 ? 172.968 74.660 -96.882 1.00 30.12 ? 117 ILE B CG1 1 ATOM 4384 C CG2 . ILE B 1 109 ? 171.978 72.705 -98.068 1.00 27.65 ? 117 ILE B CG2 1 ATOM 4385 C CD1 . ILE B 1 109 ? 174.366 74.537 -97.448 1.00 32.37 ? 117 ILE B CD1 1 ATOM 4386 N N . THR B 1 110 ? 169.107 71.940 -96.005 1.00 27.81 ? 118 THR B N 1 ATOM 4387 C CA . THR B 1 110 ? 168.462 70.671 -95.692 1.00 29.21 ? 118 THR B CA 1 ATOM 4388 C C . THR B 1 110 ? 169.298 69.530 -96.250 1.00 28.29 ? 118 THR B C 1 ATOM 4389 O O . THR B 1 110 ? 169.955 69.677 -97.284 1.00 28.06 ? 118 THR B O 1 ATOM 4390 C CB . THR B 1 110 ? 167.045 70.580 -96.296 1.00 30.59 ? 118 THR B CB 1 ATOM 4391 O OG1 . THR B 1 110 ? 167.113 70.800 -97.713 1.00 32.94 ? 118 THR B OG1 1 ATOM 4392 C CG2 . THR B 1 110 ? 166.126 71.615 -95.657 1.00 30.84 ? 118 THR B CG2 1 ATOM 4393 N N . PRO B 1 111 ? 169.282 68.371 -95.570 1.00 27.44 ? 119 PRO B N 1 ATOM 4394 C CA . PRO B 1 111 ? 170.046 67.197 -95.998 1.00 27.76 ? 119 PRO B CA 1 ATOM 4395 C C . PRO B 1 111 ? 169.411 66.515 -97.205 1.00 28.29 ? 119 PRO B C 1 ATOM 4396 O O . PRO B 1 111 ? 168.245 66.760 -97.537 1.00 29.46 ? 119 PRO B O 1 ATOM 4397 C CB . PRO B 1 111 ? 169.997 66.307 -94.769 1.00 26.80 ? 119 PRO B CB 1 ATOM 4398 C CG . PRO B 1 111 ? 168.591 66.538 -94.296 1.00 25.07 ? 119 PRO B CG 1 ATOM 4399 C CD . PRO B 1 111 ? 168.473 68.053 -94.378 1.00 26.04 ? 119 PRO B CD 1 ATOM 4400 N N . PRO B 1 112 ? 170.174 65.654 -97.890 1.00 27.96 ? 120 PRO B N 1 ATOM 4401 C CA . PRO B 1 112 ? 169.601 64.968 -99.049 1.00 28.79 ? 120 PRO B CA 1 ATOM 4402 C C . PRO B 1 112 ? 168.600 63.948 -98.525 1.00 29.29 ? 120 PRO B C 1 ATOM 4403 O O . PRO B 1 112 ? 168.614 63.625 -97.338 1.00 29.23 ? 120 PRO B O 1 ATOM 4404 C CB . PRO B 1 112 ? 170.820 64.323 -99.703 1.00 27.51 ? 120 PRO B CB 1 ATOM 4405 C CG . PRO B 1 112 ? 171.715 64.062 -98.538 1.00 28.04 ? 120 PRO B CG 1 ATOM 4406 C CD . PRO B 1 112 ? 171.597 65.324 -97.729 1.00 27.44 ? 120 PRO B CD 1 ATOM 4407 N N . GLN B 1 113 ? 167.727 63.449 -99.393 1.00 30.10 ? 121 GLN B N 1 ATOM 4408 C CA . GLN B 1 113 ? 166.736 62.465 -98.971 1.00 31.02 ? 121 GLN B CA 1 ATOM 4409 C C . GLN B 1 113 ? 167.473 61.243 -98.429 1.00 30.90 ? 121 GLN B C 1 ATOM 4410 O O . GLN B 1 113 ? 168.601 60.978 -98.840 1.00 30.85 ? 121 GLN B O 1 ATOM 4411 C CB . GLN B 1 113 ? 165.870 62.059 -100.153 1.00 32.57 ? 121 GLN B CB 1 ATOM 4412 C CG . GLN B 1 113 ? 164.666 61.250 -99.758 1.00 37.36 ? 121 GLN B CG 1 ATOM 4413 C CD . GLN B 1 113 ? 163.995 60.608 -100.948 1.00 40.56 ? 121 GLN B CD 1 ATOM 4414 O OE1 . GLN B 1 113 ? 163.795 61.248 -101.983 1.00 42.42 ? 121 GLN B OE1 1 ATOM 4415 N NE2 . GLN B 1 113 ? 163.635 59.337 -100.809 1.00 42.09 ? 121 GLN B NE2 1 ATOM 4416 N N . THR B 1 114 ? 166.852 60.496 -97.519 1.00 30.53 ? 122 THR B N 1 ATOM 4417 C CA . THR B 1 114 ? 167.526 59.326 -96.957 1.00 30.07 ? 122 THR B CA 1 ATOM 4418 C C . THR B 1 114 ? 167.752 58.282 -98.034 1.00 29.86 ? 122 THR B C 1 ATOM 4419 O O . THR B 1 114 ? 166.884 58.035 -98.866 1.00 30.98 ? 122 THR B O 1 ATOM 4420 C CB . THR B 1 114 ? 166.727 58.681 -95.803 1.00 29.73 ? 122 THR B CB 1 ATOM 4421 O OG1 . THR B 1 114 ? 165.496 58.152 -96.304 1.00 31.89 ? 122 THR B OG1 1 ATOM 4422 C CG2 . THR B 1 114 ? 166.433 59.704 -94.719 1.00 30.34 ? 122 THR B CG2 1 ATOM 4423 N N . GLY B 1 115 ? 168.932 57.676 -98.014 1.00 29.62 ? 123 GLY B N 1 ATOM 4424 C CA . GLY B 1 115 ? 169.262 56.673 -99.003 1.00 28.79 ? 123 GLY B CA 1 ATOM 4425 C C . GLY B 1 115 ? 170.396 55.762 -98.581 1.00 29.27 ? 123 GLY B C 1 ATOM 4426 O O . GLY B 1 115 ? 171.073 56.004 -97.587 1.00 30.04 ? 123 GLY B O 1 ATOM 4427 N N . LEU B 1 116 ? 170.620 54.717 -99.366 1.00 30.10 ? 124 LEU B N 1 ATOM 4428 C CA . LEU B 1 116 ? 171.656 53.743 -99.074 1.00 31.01 ? 124 LEU B CA 1 ATOM 4429 C C . LEU B 1 116 ? 173.088 54.254 -99.217 1.00 31.71 ? 124 LEU B C 1 ATOM 4430 O O . LEU B 1 116 ? 173.909 54.035 -98.328 1.00 34.01 ? 124 LEU B O 1 ATOM 4431 C CB . LEU B 1 116 ? 171.454 52.514 -99.953 1.00 30.94 ? 124 LEU B CB 1 ATOM 4432 C CG . LEU B 1 116 ? 171.843 51.175 -99.336 1.00 32.85 ? 124 LEU B CG 1 ATOM 4433 C CD1 . LEU B 1 116 ? 171.193 50.999 -97.971 1.00 32.11 ? 124 LEU B CD1 1 ATOM 4434 C CD2 . LEU B 1 116 ? 171.403 50.078 -100.276 1.00 33.56 ? 124 LEU B CD2 1 ATOM 4435 N N . ASP B 1 117 ? 173.405 54.927 -100.319 1.00 31.21 ? 125 ASP B N 1 ATOM 4436 C CA . ASP B 1 117 ? 174.770 55.421 -100.504 1.00 30.88 ? 125 ASP B CA 1 ATOM 4437 C C . ASP B 1 117 ? 174.879 56.935 -100.437 1.00 30.58 ? 125 ASP B C 1 ATOM 4438 O O . ASP B 1 117 ? 175.766 57.524 -101.066 1.00 32.41 ? 125 ASP B O 1 ATOM 4439 C CB . ASP B 1 117 ? 175.344 54.947 -101.845 1.00 29.39 ? 125 ASP B CB 1 ATOM 4440 C CG . ASP B 1 117 ? 175.350 53.442 -101.978 1.00 28.89 ? 125 ASP B CG 1 ATOM 4441 O OD1 . ASP B 1 117 ? 175.925 52.769 -101.094 1.00 28.46 ? 125 ASP B OD1 1 ATOM 4442 O OD2 . ASP B 1 117 ? 174.777 52.935 -102.964 1.00 27.67 ? 125 ASP B OD2 1 ATOM 4443 N N . VAL B 1 118 ? 173.990 57.571 -99.681 1.00 28.63 ? 126 VAL B N 1 ATOM 4444 C CA . VAL B 1 118 ? 174.026 59.021 -99.572 1.00 26.72 ? 126 VAL B CA 1 ATOM 4445 C C . VAL B 1 118 ? 175.136 59.481 -98.643 1.00 26.11 ? 126 VAL B C 1 ATOM 4446 O O . VAL B 1 118 ? 175.123 59.185 -97.442 1.00 26.44 ? 126 VAL B O 1 ATOM 4447 C CB . VAL B 1 118 ? 172.695 59.588 -99.053 1.00 26.76 ? 126 VAL B CB 1 ATOM 4448 C CG1 . VAL B 1 118 ? 172.792 61.092 -98.944 1.00 24.62 ? 126 VAL B CG1 1 ATOM 4449 C CG2 . VAL B 1 118 ? 171.566 59.202 -99.989 1.00 26.72 ? 126 VAL B CG2 1 ATOM 4450 N N . PRO B 1 119 ? 176.124 60.211 -99.190 1.00 25.50 ? 127 PRO B N 1 ATOM 4451 C CA . PRO B 1 119 ? 177.235 60.702 -98.368 1.00 24.63 ? 127 PRO B CA 1 ATOM 4452 C C . PRO B 1 119 ? 176.824 61.852 -97.451 1.00 24.04 ? 127 PRO B C 1 ATOM 4453 O O . PRO B 1 119 ? 175.948 62.660 -97.779 1.00 23.83 ? 127 PRO B O 1 ATOM 4454 C CB . PRO B 1 119 ? 178.273 61.128 -99.407 1.00 21.60 ? 127 PRO B CB 1 ATOM 4455 C CG . PRO B 1 119 ? 177.426 61.589 -100.541 1.00 22.43 ? 127 PRO B CG 1 ATOM 4456 C CD . PRO B 1 119 ? 176.350 60.520 -100.614 1.00 23.12 ? 127 PRO B CD 1 ATOM 4457 N N . TYR B 1 120 ? 177.464 61.911 -96.293 1.00 23.77 ? 128 TYR B N 1 ATOM 4458 C CA . TYR B 1 120 ? 177.193 62.963 -95.333 1.00 23.64 ? 128 TYR B CA 1 ATOM 4459 C C . TYR B 1 120 ? 178.315 62.982 -94.317 1.00 23.65 ? 128 TYR B C 1 ATOM 4460 O O . TYR B 1 120 ? 178.861 61.933 -93.969 1.00 24.76 ? 128 TYR B O 1 ATOM 4461 C CB . TYR B 1 120 ? 175.872 62.716 -94.618 1.00 22.88 ? 128 TYR B CB 1 ATOM 4462 C CG . TYR B 1 120 ? 175.219 63.990 -94.154 1.00 21.57 ? 128 TYR B CG 1 ATOM 4463 C CD1 . TYR B 1 120 ? 174.628 64.857 -95.070 1.00 21.01 ? 128 TYR B CD1 1 ATOM 4464 C CD2 . TYR B 1 120 ? 175.212 64.347 -92.807 1.00 20.69 ? 128 TYR B CD2 1 ATOM 4465 C CE1 . TYR B 1 120 ? 174.044 66.046 -94.662 1.00 21.55 ? 128 TYR B CE1 1 ATOM 4466 C CE2 . TYR B 1 120 ? 174.632 65.536 -92.385 1.00 20.78 ? 128 TYR B CE2 1 ATOM 4467 C CZ . TYR B 1 120 ? 174.047 66.380 -93.319 1.00 22.39 ? 128 TYR B CZ 1 ATOM 4468 O OH . TYR B 1 120 ? 173.449 67.554 -92.915 1.00 24.87 ? 128 TYR B OH 1 ATOM 4469 N N . THR B 1 121 ? 178.680 64.167 -93.851 1.00 23.80 ? 129 THR B N 1 ATOM 4470 C CA . THR B 1 121 ? 179.745 64.251 -92.869 1.00 25.29 ? 129 THR B CA 1 ATOM 4471 C C . THR B 1 121 ? 179.238 64.923 -91.589 1.00 25.30 ? 129 THR B C 1 ATOM 4472 O O . THR B 1 121 ? 178.733 66.050 -91.614 1.00 26.59 ? 129 THR B O 1 ATOM 4473 C CB . THR B 1 121 ? 181.013 64.962 -93.464 1.00 25.20 ? 129 THR B CB 1 ATOM 4474 O OG1 . THR B 1 121 ? 181.600 65.817 -92.477 1.00 27.06 ? 129 THR B OG1 1 ATOM 4475 C CG2 . THR B 1 121 ? 180.673 65.745 -94.728 1.00 25.74 ? 129 THR B CG2 1 ATOM 4476 N N . PHE B 1 122 ? 179.346 64.188 -90.482 1.00 24.03 ? 130 PHE B N 1 ATOM 4477 C CA . PHE B 1 122 ? 178.887 64.633 -89.170 1.00 22.39 ? 130 PHE B CA 1 ATOM 4478 C C . PHE B 1 122 ? 180.032 65.116 -88.306 1.00 23.09 ? 130 PHE B C 1 ATOM 4479 O O . PHE B 1 122 ? 181.162 64.645 -88.421 1.00 23.73 ? 130 PHE B O 1 ATOM 4480 C CB . PHE B 1 122 ? 178.206 63.480 -88.422 1.00 20.63 ? 130 PHE B CB 1 ATOM 4481 C CG . PHE B 1 122 ? 176.895 63.042 -89.010 1.00 19.83 ? 130 PHE B CG 1 ATOM 4482 C CD1 . PHE B 1 122 ? 175.727 63.747 -88.739 1.00 19.13 ? 130 PHE B CD1 1 ATOM 4483 C CD2 . PHE B 1 122 ? 176.817 61.893 -89.799 1.00 18.76 ? 130 PHE B CD2 1 ATOM 4484 C CE1 . PHE B 1 122 ? 174.499 63.307 -89.241 1.00 18.16 ? 130 PHE B CE1 1 ATOM 4485 C CE2 . PHE B 1 122 ? 175.594 61.450 -90.304 1.00 18.09 ? 130 PHE B CE2 1 ATOM 4486 C CZ . PHE B 1 122 ? 174.438 62.155 -90.023 1.00 17.99 ? 130 PHE B CZ 1 ATOM 4487 N N . GLY B 1 123 ? 179.721 66.052 -87.422 1.00 24.03 ? 131 GLY B N 1 ATOM 4488 C CA . GLY B 1 123 ? 180.715 66.564 -86.502 1.00 23.64 ? 131 GLY B CA 1 ATOM 4489 C C . GLY B 1 123 ? 180.441 65.913 -85.154 1.00 23.24 ? 131 GLY B C 1 ATOM 4490 O O . GLY B 1 123 ? 179.298 65.549 -84.863 1.00 22.47 ? 131 GLY B O 1 ATOM 4491 N N . LEU B 1 124 ? 181.481 65.753 -84.340 1.00 22.56 ? 132 LEU B N 1 ATOM 4492 C CA . LEU B 1 124 ? 181.345 65.147 -83.024 1.00 22.24 ? 132 LEU B CA 1 ATOM 4493 C C . LEU B 1 124 ? 181.999 66.032 -81.976 1.00 22.62 ? 132 LEU B C 1 ATOM 4494 O O . LEU B 1 124 ? 183.212 66.204 -81.964 1.00 23.39 ? 132 LEU B O 1 ATOM 4495 C CB . LEU B 1 124 ? 181.971 63.760 -83.035 1.00 20.68 ? 132 LEU B CB 1 ATOM 4496 C CG . LEU B 1 124 ? 181.014 62.803 -83.745 1.00 22.52 ? 132 LEU B CG 1 ATOM 4497 C CD1 . LEU B 1 124 ? 181.757 61.884 -84.687 1.00 24.77 ? 132 LEU B CD1 1 ATOM 4498 C CD2 . LEU B 1 124 ? 180.245 62.030 -82.696 1.00 21.28 ? 132 LEU B CD2 1 ATOM 4499 N N . ILE B 1 125 ? 181.171 66.599 -81.107 1.00 22.61 ? 133 ILE B N 1 ATOM 4500 C CA . ILE B 1 125 ? 181.622 67.492 -80.054 1.00 22.31 ? 133 ILE B CA 1 ATOM 4501 C C . ILE B 1 125 ? 180.960 67.062 -78.747 1.00 23.28 ? 133 ILE B C 1 ATOM 4502 O O . ILE B 1 125 ? 179.764 66.753 -78.722 1.00 23.59 ? 133 ILE B O 1 ATOM 4503 C CB . ILE B 1 125 ? 181.215 68.942 -80.380 1.00 21.59 ? 133 ILE B CB 1 ATOM 4504 C CG1 . ILE B 1 125 ? 181.940 69.409 -81.642 1.00 22.24 ? 133 ILE B CG1 1 ATOM 4505 C CG2 . ILE B 1 125 ? 181.521 69.857 -79.220 1.00 21.06 ? 133 ILE B CG2 1 ATOM 4506 C CD1 . ILE B 1 125 ? 181.549 70.814 -82.090 1.00 22.88 ? 133 ILE B CD1 1 ATOM 4507 N N . GLY B 1 126 ? 181.737 67.027 -77.669 1.00 22.34 ? 134 GLY B N 1 ATOM 4508 C CA . GLY B 1 126 ? 181.184 66.632 -76.388 1.00 21.23 ? 134 GLY B CA 1 ATOM 4509 C C . GLY B 1 126 ? 181.748 67.451 -75.246 1.00 20.82 ? 134 GLY B C 1 ATOM 4510 O O . GLY B 1 126 ? 182.923 67.818 -75.272 1.00 21.17 ? 134 GLY B O 1 ATOM 4511 N N . ASP B 1 127 ? 180.922 67.742 -74.243 1.00 20.52 ? 135 ASP B N 1 ATOM 4512 C CA . ASP B 1 127 ? 181.370 68.513 -73.087 1.00 20.18 ? 135 ASP B CA 1 ATOM 4513 C C . ASP B 1 127 ? 182.107 69.775 -73.544 1.00 19.81 ? 135 ASP B C 1 ATOM 4514 O O . ASP B 1 127 ? 183.242 70.026 -73.134 1.00 18.02 ? 135 ASP B O 1 ATOM 4515 C CB . ASP B 1 127 ? 182.299 67.646 -72.222 1.00 21.18 ? 135 ASP B CB 1 ATOM 4516 C CG . ASP B 1 127 ? 181.657 66.324 -71.817 1.00 21.47 ? 135 ASP B CG 1 ATOM 4517 O OD1 . ASP B 1 127 ? 181.487 65.444 -72.683 1.00 20.75 ? 135 ASP B OD1 1 ATOM 4518 O OD2 . ASP B 1 127 ? 181.313 66.161 -70.627 1.00 24.22 ? 135 ASP B OD2 1 ATOM 4519 N N . LEU B 1 128 ? 181.449 70.564 -74.393 1.00 20.89 ? 136 LEU B N 1 ATOM 4520 C CA . LEU B 1 128 ? 182.030 71.790 -74.940 1.00 21.05 ? 136 LEU B CA 1 ATOM 4521 C C . LEU B 1 128 ? 182.375 72.823 -73.870 1.00 22.09 ? 136 LEU B C 1 ATOM 4522 O O . LEU B 1 128 ? 183.540 73.171 -73.682 1.00 22.72 ? 136 LEU B O 1 ATOM 4523 C CB . LEU B 1 128 ? 181.077 72.409 -75.973 1.00 18.60 ? 136 LEU B CB 1 ATOM 4524 C CG . LEU B 1 128 ? 181.535 73.687 -76.691 1.00 18.30 ? 136 LEU B CG 1 ATOM 4525 C CD1 . LEU B 1 128 ? 182.943 73.503 -77.240 1.00 16.95 ? 136 LEU B CD1 1 ATOM 4526 C CD2 . LEU B 1 128 ? 180.566 74.019 -77.813 1.00 17.74 ? 136 LEU B CD2 1 ATOM 4527 N N . GLY B 1 129 ? 181.362 73.301 -73.160 1.00 23.16 ? 137 GLY B N 1 ATOM 4528 C CA . GLY B 1 129 ? 181.602 74.298 -72.134 1.00 23.48 ? 137 GLY B CA 1 ATOM 4529 C C . GLY B 1 129 ? 181.835 75.655 -72.767 1.00 23.52 ? 137 GLY B C 1 ATOM 4530 O O . GLY B 1 129 ? 181.481 75.865 -73.928 1.00 23.35 ? 137 GLY B O 1 ATOM 4531 N N . GLN B 1 130 ? 182.432 76.577 -72.019 1.00 23.92 ? 138 GLN B N 1 ATOM 4532 C CA . GLN B 1 130 ? 182.697 77.908 -72.548 1.00 24.73 ? 138 GLN B CA 1 ATOM 4533 C C . GLN B 1 130 ? 184.022 78.490 -72.050 1.00 25.58 ? 138 GLN B C 1 ATOM 4534 O O . GLN B 1 130 ? 184.095 79.636 -71.602 1.00 25.23 ? 138 GLN B O 1 ATOM 4535 C CB . GLN B 1 130 ? 181.529 78.844 -72.211 1.00 24.79 ? 138 GLN B CB 1 ATOM 4536 C CG . GLN B 1 130 ? 181.163 78.928 -70.730 1.00 24.53 ? 138 GLN B CG 1 ATOM 4537 C CD . GLN B 1 130 ? 179.816 79.597 -70.502 1.00 24.44 ? 138 GLN B CD 1 ATOM 4538 O OE1 . GLN B 1 130 ? 178.821 78.934 -70.190 1.00 25.44 ? 138 GLN B OE1 1 ATOM 4539 N NE2 . GLN B 1 130 ? 179.772 80.909 -70.674 1.00 22.89 ? 138 GLN B NE2 1 ATOM 4540 N N . SER B 1 131 ? 185.072 77.681 -72.129 1.00 25.79 ? 139 SER B N 1 ATOM 4541 C CA . SER B 1 131 ? 186.407 78.094 -71.720 1.00 25.57 ? 139 SER B CA 1 ATOM 4542 C C . SER B 1 131 ? 187.175 78.445 -72.994 1.00 26.98 ? 139 SER B C 1 ATOM 4543 O O . SER B 1 131 ? 186.706 78.183 -74.107 1.00 26.75 ? 139 SER B O 1 ATOM 4544 C CB . SER B 1 131 ? 187.118 76.953 -70.990 1.00 23.85 ? 139 SER B CB 1 ATOM 4545 O OG . SER B 1 131 ? 187.291 75.844 -71.855 1.00 21.29 ? 139 SER B OG 1 ATOM 4546 N N . PHE B 1 132 ? 188.350 79.041 -72.835 1.00 27.39 ? 140 PHE B N 1 ATOM 4547 C CA . PHE B 1 132 ? 189.148 79.407 -73.990 1.00 26.95 ? 140 PHE B CA 1 ATOM 4548 C C . PHE B 1 132 ? 189.379 78.186 -74.868 1.00 26.93 ? 140 PHE B C 1 ATOM 4549 O O . PHE B 1 132 ? 189.333 78.276 -76.091 1.00 28.12 ? 140 PHE B O 1 ATOM 4550 C CB . PHE B 1 132 ? 190.469 80.019 -73.533 1.00 27.28 ? 140 PHE B CB 1 ATOM 4551 C CG . PHE B 1 132 ? 190.316 81.397 -72.943 1.00 28.36 ? 140 PHE B CG 1 ATOM 4552 C CD1 . PHE B 1 132 ? 190.047 82.488 -73.763 1.00 28.11 ? 140 PHE B CD1 1 ATOM 4553 C CD2 . PHE B 1 132 ? 190.389 81.598 -71.562 1.00 29.70 ? 140 PHE B CD2 1 ATOM 4554 C CE1 . PHE B 1 132 ? 189.849 83.762 -73.219 1.00 28.42 ? 140 PHE B CE1 1 ATOM 4555 C CE2 . PHE B 1 132 ? 190.192 82.874 -71.004 1.00 28.84 ? 140 PHE B CE2 1 ATOM 4556 C CZ . PHE B 1 132 ? 189.922 83.954 -71.835 1.00 27.81 ? 140 PHE B CZ 1 ATOM 4557 N N . ASP B 1 133 ? 189.608 77.038 -74.246 1.00 26.97 ? 141 ASP B N 1 ATOM 4558 C CA . ASP B 1 133 ? 189.824 75.812 -75.002 1.00 27.67 ? 141 ASP B CA 1 ATOM 4559 C C . ASP B 1 133 ? 188.591 75.489 -75.865 1.00 28.13 ? 141 ASP B C 1 ATOM 4560 O O . ASP B 1 133 ? 188.714 75.051 -77.018 1.00 26.93 ? 141 ASP B O 1 ATOM 4561 C CB . ASP B 1 133 ? 190.123 74.656 -74.040 1.00 29.61 ? 141 ASP B CB 1 ATOM 4562 C CG . ASP B 1 133 ? 191.435 74.844 -73.290 1.00 31.14 ? 141 ASP B CG 1 ATOM 4563 O OD1 . ASP B 1 133 ? 192.488 74.944 -73.953 1.00 32.64 ? 141 ASP B OD1 1 ATOM 4564 O OD2 . ASP B 1 133 ? 191.417 74.891 -72.040 1.00 32.10 ? 141 ASP B OD2 1 ATOM 4565 N N . SER B 1 134 ? 187.405 75.713 -75.304 1.00 28.02 ? 142 SER B N 1 ATOM 4566 C CA . SER B 1 134 ? 186.152 75.459 -76.010 1.00 27.59 ? 142 SER B CA 1 ATOM 4567 C C . SER B 1 134 ? 186.078 76.252 -77.318 1.00 27.77 ? 142 SER B C 1 ATOM 4568 O O . SER B 1 134 ? 185.600 75.749 -78.339 1.00 27.59 ? 142 SER B O 1 ATOM 4569 C CB . SER B 1 134 ? 184.966 75.851 -75.125 1.00 27.67 ? 142 SER B CB 1 ATOM 4570 O OG . SER B 1 134 ? 185.127 75.348 -73.812 1.00 27.38 ? 142 SER B OG 1 ATOM 4571 N N . ASN B 1 135 ? 186.547 77.498 -77.276 1.00 27.67 ? 143 ASN B N 1 ATOM 4572 C CA . ASN B 1 135 ? 186.522 78.369 -78.449 1.00 25.96 ? 143 ASN B CA 1 ATOM 4573 C C . ASN B 1 135 ? 187.462 77.841 -79.516 1.00 24.86 ? 143 ASN B C 1 ATOM 4574 O O . ASN B 1 135 ? 187.152 77.881 -80.713 1.00 24.23 ? 143 ASN B O 1 ATOM 4575 C CB . ASN B 1 135 ? 186.911 79.797 -78.056 1.00 26.58 ? 143 ASN B CB 1 ATOM 4576 C CG . ASN B 1 135 ? 186.604 80.799 -79.143 1.00 28.31 ? 143 ASN B CG 1 ATOM 4577 O OD1 . ASN B 1 135 ? 185.576 80.689 -79.813 1.00 28.00 ? 143 ASN B OD1 1 ATOM 4578 N ND2 . ASN B 1 135 ? 187.477 81.791 -79.311 1.00 31.11 ? 143 ASN B ND2 1 ATOM 4579 N N . THR B 1 136 ? 188.614 77.343 -79.080 1.00 22.96 ? 144 THR B N 1 ATOM 4580 C CA . THR B 1 136 ? 189.588 76.793 -80.010 1.00 21.71 ? 144 THR B CA 1 ATOM 4581 C C . THR B 1 136 ? 188.983 75.577 -80.695 1.00 21.70 ? 144 THR B C 1 ATOM 4582 O O . THR B 1 136 ? 189.092 75.422 -81.910 1.00 22.43 ? 144 THR B O 1 ATOM 4583 C CB . THR B 1 136 ? 190.867 76.357 -79.294 1.00 21.84 ? 144 THR B CB 1 ATOM 4584 O OG1 . THR B 1 136 ? 191.449 77.488 -78.635 1.00 23.71 ? 144 THR B OG1 1 ATOM 4585 C CG2 . THR B 1 136 ? 191.858 75.767 -80.291 1.00 19.68 ? 144 THR B CG2 1 ATOM 4586 N N . THR B 1 137 ? 188.339 74.711 -79.919 1.00 21.07 ? 145 THR B N 1 ATOM 4587 C CA . THR B 1 137 ? 187.734 73.524 -80.503 1.00 20.89 ? 145 THR B CA 1 ATOM 4588 C C . THR B 1 137 ? 186.680 73.916 -81.527 1.00 20.84 ? 145 THR B C 1 ATOM 4589 O O . THR B 1 137 ? 186.657 73.376 -82.633 1.00 21.42 ? 145 THR B O 1 ATOM 4590 C CB . THR B 1 137 ? 187.069 72.622 -79.445 1.00 19.91 ? 145 THR B CB 1 ATOM 4591 O OG1 . THR B 1 137 ? 188.030 72.256 -78.450 1.00 19.91 ? 145 THR B OG1 1 ATOM 4592 C CG2 . THR B 1 137 ? 186.537 71.350 -80.102 1.00 18.38 ? 145 THR B CG2 1 ATOM 4593 N N . LEU B 1 138 ? 185.812 74.860 -81.174 1.00 21.22 ? 146 LEU B N 1 ATOM 4594 C CA . LEU B 1 138 ? 184.775 75.280 -82.107 1.00 21.31 ? 146 LEU B CA 1 ATOM 4595 C C . LEU B 1 138 ? 185.383 75.840 -83.395 1.00 21.88 ? 146 LEU B C 1 ATOM 4596 O O . LEU B 1 138 ? 184.847 75.616 -84.485 1.00 20.65 ? 146 LEU B O 1 ATOM 4597 C CB . LEU B 1 138 ? 183.854 76.317 -81.456 1.00 22.65 ? 146 LEU B CB 1 ATOM 4598 C CG . LEU B 1 138 ? 182.614 76.679 -82.290 1.00 24.12 ? 146 LEU B CG 1 ATOM 4599 C CD1 . LEU B 1 138 ? 181.836 75.413 -82.652 1.00 23.75 ? 146 LEU B CD1 1 ATOM 4600 C CD2 . LEU B 1 138 ? 181.732 77.644 -81.513 1.00 24.00 ? 146 LEU B CD2 1 ATOM 4601 N N . SER B 1 139 ? 186.500 76.561 -83.270 1.00 22.99 ? 147 SER B N 1 ATOM 4602 C CA . SER B 1 139 ? 187.187 77.127 -84.433 1.00 23.74 ? 147 SER B CA 1 ATOM 4603 C C . SER B 1 139 ? 187.666 76.026 -85.364 1.00 24.78 ? 147 SER B C 1 ATOM 4604 O O . SER B 1 139 ? 187.371 76.055 -86.560 1.00 25.19 ? 147 SER B O 1 ATOM 4605 C CB . SER B 1 139 ? 188.392 77.963 -84.010 1.00 23.69 ? 147 SER B CB 1 ATOM 4606 O OG . SER B 1 139 ? 188.003 79.124 -83.305 1.00 27.21 ? 147 SER B OG 1 ATOM 4607 N N . HIS B 1 140 ? 188.400 75.056 -84.822 1.00 25.10 ? 148 HIS B N 1 ATOM 4608 C CA . HIS B 1 140 ? 188.907 73.957 -85.638 1.00 26.98 ? 148 HIS B CA 1 ATOM 4609 C C . HIS B 1 140 ? 187.801 73.254 -86.405 1.00 27.76 ? 148 HIS B C 1 ATOM 4610 O O . HIS B 1 140 ? 187.993 72.861 -87.557 1.00 28.23 ? 148 HIS B O 1 ATOM 4611 C CB . HIS B 1 140 ? 189.656 72.932 -84.782 1.00 30.59 ? 148 HIS B CB 1 ATOM 4612 C CG . HIS B 1 140 ? 191.009 73.391 -84.333 1.00 32.96 ? 148 HIS B CG 1 ATOM 4613 N ND1 . HIS B 1 140 ? 192.091 72.541 -84.257 1.00 34.26 ? 148 HIS B ND1 1 ATOM 4614 C CD2 . HIS B 1 140 ? 191.450 74.603 -83.921 1.00 33.99 ? 148 HIS B CD2 1 ATOM 4615 C CE1 . HIS B 1 140 ? 193.143 73.212 -83.818 1.00 35.12 ? 148 HIS B CE1 1 ATOM 4616 N NE2 . HIS B 1 140 ? 192.781 74.464 -83.607 1.00 35.42 ? 148 HIS B NE2 1 ATOM 4617 N N . TYR B 1 141 ? 186.641 73.094 -85.773 1.00 27.60 ? 149 TYR B N 1 ATOM 4618 C CA . TYR B 1 141 ? 185.517 72.442 -86.436 1.00 26.79 ? 149 TYR B CA 1 ATOM 4619 C C . TYR B 1 141 ? 185.015 73.287 -87.619 1.00 28.74 ? 149 TYR B C 1 ATOM 4620 O O . TYR B 1 141 ? 184.650 72.747 -88.668 1.00 28.98 ? 149 TYR B O 1 ATOM 4621 C CB . TYR B 1 141 ? 184.374 72.199 -85.443 1.00 22.47 ? 149 TYR B CB 1 ATOM 4622 C CG . TYR B 1 141 ? 183.125 71.692 -86.114 1.00 18.74 ? 149 TYR B CG 1 ATOM 4623 C CD1 . TYR B 1 141 ? 183.066 70.400 -86.624 1.00 18.88 ? 149 TYR B CD1 1 ATOM 4624 C CD2 . TYR B 1 141 ? 182.032 72.528 -86.312 1.00 17.36 ? 149 TYR B CD2 1 ATOM 4625 C CE1 . TYR B 1 141 ? 181.952 69.951 -87.325 1.00 16.86 ? 149 TYR B CE1 1 ATOM 4626 C CE2 . TYR B 1 141 ? 180.911 72.091 -87.012 1.00 16.27 ? 149 TYR B CE2 1 ATOM 4627 C CZ . TYR B 1 141 ? 180.882 70.799 -87.516 1.00 16.79 ? 149 TYR B CZ 1 ATOM 4628 O OH . TYR B 1 141 ? 179.798 70.341 -88.229 1.00 17.02 ? 149 TYR B OH 1 ATOM 4629 N N . GLU B 1 142 ? 185.007 74.609 -87.447 1.00 30.19 ? 150 GLU B N 1 ATOM 4630 C CA . GLU B 1 142 ? 184.554 75.526 -88.498 1.00 31.90 ? 150 GLU B CA 1 ATOM 4631 C C . GLU B 1 142 ? 185.540 75.581 -89.653 1.00 31.81 ? 150 GLU B C 1 ATOM 4632 O O . GLU B 1 142 ? 185.141 75.635 -90.812 1.00 32.79 ? 150 GLU B O 1 ATOM 4633 C CB . GLU B 1 142 ? 184.396 76.949 -87.959 1.00 32.50 ? 150 GLU B CB 1 ATOM 4634 C CG . GLU B 1 142 ? 183.433 77.108 -86.810 1.00 36.46 ? 150 GLU B CG 1 ATOM 4635 C CD . GLU B 1 142 ? 183.511 78.492 -86.195 1.00 40.07 ? 150 GLU B CD 1 ATOM 4636 O OE1 . GLU B 1 142 ? 184.639 78.932 -85.865 1.00 41.54 ? 150 GLU B OE1 1 ATOM 4637 O OE2 . GLU B 1 142 ? 182.450 79.138 -86.043 1.00 41.40 ? 150 GLU B OE2 1 ATOM 4638 N N . LEU B 1 143 ? 186.829 75.578 -89.329 1.00 32.08 ? 151 LEU B N 1 ATOM 4639 C CA . LEU B 1 143 ? 187.875 75.654 -90.341 1.00 32.56 ? 151 LEU B CA 1 ATOM 4640 C C . LEU B 1 143 ? 188.226 74.297 -90.928 1.00 33.47 ? 151 LEU B C 1 ATOM 4641 O O . LEU B 1 143 ? 189.030 74.212 -91.850 1.00 35.18 ? 151 LEU B O 1 ATOM 4642 C CB . LEU B 1 143 ? 189.133 76.296 -89.751 1.00 30.95 ? 151 LEU B CB 1 ATOM 4643 C CG . LEU B 1 143 ? 188.943 77.678 -89.111 1.00 31.23 ? 151 LEU B CG 1 ATOM 4644 C CD1 . LEU B 1 143 ? 190.261 78.156 -88.529 1.00 30.08 ? 151 LEU B CD1 1 ATOM 4645 C CD2 . LEU B 1 143 ? 188.417 78.667 -90.142 1.00 29.57 ? 151 LEU B CD2 1 ATOM 4646 N N . SER B 1 144 ? 187.626 73.238 -90.401 1.00 34.59 ? 152 SER B N 1 ATOM 4647 C CA . SER B 1 144 ? 187.899 71.897 -90.903 1.00 36.43 ? 152 SER B CA 1 ATOM 4648 C C . SER B 1 144 ? 187.839 71.872 -92.423 1.00 38.14 ? 152 SER B C 1 ATOM 4649 O O . SER B 1 144 ? 186.883 72.363 -93.021 1.00 37.96 ? 152 SER B O 1 ATOM 4650 C CB . SER B 1 144 ? 186.882 70.893 -90.351 1.00 36.79 ? 152 SER B CB 1 ATOM 4651 O OG . SER B 1 144 ? 187.063 69.610 -90.930 1.00 36.77 ? 152 SER B OG 1 ATOM 4652 N N . PRO B 1 145 ? 188.865 71.298 -93.068 1.00 39.73 ? 153 PRO B N 1 ATOM 4653 C CA . PRO B 1 145 ? 188.897 71.223 -94.532 1.00 40.81 ? 153 PRO B CA 1 ATOM 4654 C C . PRO B 1 145 ? 187.716 70.421 -95.080 1.00 42.52 ? 153 PRO B C 1 ATOM 4655 O O . PRO B 1 145 ? 187.169 70.759 -96.128 1.00 43.65 ? 153 PRO B O 1 ATOM 4656 C CB . PRO B 1 145 ? 190.247 70.567 -94.815 1.00 40.42 ? 153 PRO B CB 1 ATOM 4657 C CG . PRO B 1 145 ? 190.455 69.689 -93.605 1.00 41.90 ? 153 PRO B CG 1 ATOM 4658 C CD . PRO B 1 145 ? 190.023 70.604 -92.477 1.00 40.85 ? 153 PRO B CD 1 ATOM 4659 N N . LYS B 1 146 ? 187.327 69.360 -94.373 1.00 44.04 ? 154 LYS B N 1 ATOM 4660 C CA . LYS B 1 146 ? 186.187 68.531 -94.778 1.00 45.80 ? 154 LYS B CA 1 ATOM 4661 C C . LYS B 1 146 ? 184.970 69.044 -94.007 1.00 45.56 ? 154 LYS B C 1 ATOM 4662 O O . LYS B 1 146 ? 184.554 68.451 -93.023 1.00 47.62 ? 154 LYS B O 1 ATOM 4663 C CB . LYS B 1 146 ? 186.457 67.060 -94.442 1.00 47.91 ? 154 LYS B CB 1 ATOM 4664 C CG . LYS B 1 146 ? 187.236 66.870 -93.134 1.00 53.16 ? 154 LYS B CG 1 ATOM 4665 C CD . LYS B 1 146 ? 187.544 65.400 -92.823 1.00 55.55 ? 154 LYS B CD 1 ATOM 4666 C CE . LYS B 1 146 ? 188.681 65.281 -91.791 1.00 57.63 ? 154 LYS B CE 1 ATOM 4667 N NZ . LYS B 1 146 ? 188.454 66.027 -90.501 1.00 58.46 ? 154 LYS B NZ 1 ATOM 4668 N N . LYS B 1 147 ? 184.422 70.166 -94.457 1.00 44.23 ? 155 LYS B N 1 ATOM 4669 C CA . LYS B 1 147 ? 183.276 70.809 -93.820 1.00 42.79 ? 155 LYS B CA 1 ATOM 4670 C C . LYS B 1 147 ? 182.237 69.886 -93.193 1.00 40.22 ? 155 LYS B C 1 ATOM 4671 O O . LYS B 1 147 ? 181.745 68.956 -93.839 1.00 39.41 ? 155 LYS B O 1 ATOM 4672 C CB . LYS B 1 147 ? 182.589 71.724 -94.832 1.00 46.16 ? 155 LYS B CB 1 ATOM 4673 C CG . LYS B 1 147 ? 182.611 71.175 -96.259 1.00 51.89 ? 155 LYS B CG 1 ATOM 4674 C CD . LYS B 1 147 ? 181.202 71.068 -96.872 1.00 56.70 ? 155 LYS B CD 1 ATOM 4675 C CE . LYS B 1 147 ? 180.362 69.942 -96.237 1.00 58.74 ? 155 LYS B CE 1 ATOM 4676 N NZ . LYS B 1 147 ? 180.929 68.559 -96.441 1.00 59.00 ? 155 LYS B NZ 1 ATOM 4677 N N . GLY B 1 148 ? 181.908 70.157 -91.929 1.00 36.76 ? 156 GLY B N 1 ATOM 4678 C CA . GLY B 1 148 ? 180.910 69.369 -91.227 1.00 32.62 ? 156 GLY B CA 1 ATOM 4679 C C . GLY B 1 148 ? 179.543 69.918 -91.577 1.00 29.57 ? 156 GLY B C 1 ATOM 4680 O O . GLY B 1 148 ? 179.394 71.126 -91.710 1.00 29.03 ? 156 GLY B O 1 ATOM 4681 N N . GLN B 1 149 ? 178.546 69.050 -91.727 1.00 27.24 ? 157 GLN B N 1 ATOM 4682 C CA . GLN B 1 149 ? 177.204 69.501 -92.096 1.00 26.08 ? 157 GLN B CA 1 ATOM 4683 C C . GLN B 1 149 ? 176.159 69.422 -90.979 1.00 24.05 ? 157 GLN B C 1 ATOM 4684 O O . GLN B 1 149 ? 175.053 69.937 -91.117 1.00 23.63 ? 157 GLN B O 1 ATOM 4685 C CB . GLN B 1 149 ? 176.710 68.701 -93.296 1.00 25.43 ? 157 GLN B CB 1 ATOM 4686 C CG . GLN B 1 149 ? 177.750 68.513 -94.363 1.00 26.53 ? 157 GLN B CG 1 ATOM 4687 C CD . GLN B 1 149 ? 177.240 67.649 -95.488 1.00 28.23 ? 157 GLN B CD 1 ATOM 4688 O OE1 . GLN B 1 149 ? 176.456 68.100 -96.318 1.00 29.37 ? 157 GLN B OE1 1 ATOM 4689 N NE2 . GLN B 1 149 ? 177.668 66.390 -95.514 1.00 28.31 ? 157 GLN B NE2 1 ATOM 4690 N N . THR B 1 150 ? 176.513 68.761 -89.888 1.00 22.21 ? 158 THR B N 1 ATOM 4691 C CA . THR B 1 150 ? 175.631 68.600 -88.743 1.00 21.41 ? 158 THR B CA 1 ATOM 4692 C C . THR B 1 150 ? 176.503 68.088 -87.598 1.00 20.90 ? 158 THR B C 1 ATOM 4693 O O . THR B 1 150 ? 177.407 67.277 -87.800 1.00 21.17 ? 158 THR B O 1 ATOM 4694 C CB . THR B 1 150 ? 174.494 67.567 -89.023 1.00 20.47 ? 158 THR B CB 1 ATOM 4695 O OG1 . THR B 1 150 ? 173.587 68.091 -90.001 1.00 19.14 ? 158 THR B OG1 1 ATOM 4696 C CG2 . THR B 1 150 ? 173.720 67.258 -87.741 1.00 19.43 ? 158 THR B CG2 1 ATOM 4697 N N . VAL B 1 151 ? 176.241 68.573 -86.396 1.00 20.22 ? 159 VAL B N 1 ATOM 4698 C CA . VAL B 1 151 ? 177.018 68.158 -85.242 1.00 21.08 ? 159 VAL B CA 1 ATOM 4699 C C . VAL B 1 151 ? 176.210 67.227 -84.358 1.00 20.92 ? 159 VAL B C 1 ATOM 4700 O O . VAL B 1 151 ? 175.002 67.412 -84.177 1.00 21.86 ? 159 VAL B O 1 ATOM 4701 C CB . VAL B 1 151 ? 177.449 69.381 -84.378 1.00 21.52 ? 159 VAL B CB 1 ATOM 4702 C CG1 . VAL B 1 151 ? 178.031 68.911 -83.051 1.00 19.88 ? 159 VAL B CG1 1 ATOM 4703 C CG2 . VAL B 1 151 ? 178.474 70.226 -85.132 1.00 20.38 ? 159 VAL B CG2 1 ATOM 4704 N N . LEU B 1 152 ? 176.872 66.212 -83.824 1.00 19.60 ? 160 LEU B N 1 ATOM 4705 C CA . LEU B 1 152 ? 176.215 65.295 -82.914 1.00 18.83 ? 160 LEU B CA 1 ATOM 4706 C C . LEU B 1 152 ? 176.816 65.678 -81.563 1.00 20.19 ? 160 LEU B C 1 ATOM 4707 O O . LEU B 1 152 ? 178.021 65.493 -81.340 1.00 20.20 ? 160 LEU B O 1 ATOM 4708 C CB . LEU B 1 152 ? 176.540 63.845 -83.280 1.00 16.71 ? 160 LEU B CB 1 ATOM 4709 C CG . LEU B 1 152 ? 176.150 63.425 -84.706 1.00 16.38 ? 160 LEU B CG 1 ATOM 4710 C CD1 . LEU B 1 152 ? 176.393 61.932 -84.863 1.00 15.46 ? 160 LEU B CD1 1 ATOM 4711 C CD2 . LEU B 1 152 ? 174.684 63.756 -85.000 1.00 11.94 ? 160 LEU B CD2 1 ATOM 4712 N N . PHE B 1 153 ? 175.986 66.256 -80.691 1.00 20.01 ? 161 PHE B N 1 ATOM 4713 C CA . PHE B 1 153 ? 176.438 66.696 -79.377 1.00 20.04 ? 161 PHE B CA 1 ATOM 4714 C C . PHE B 1 153 ? 176.199 65.605 -78.356 1.00 20.94 ? 161 PHE B C 1 ATOM 4715 O O . PHE B 1 153 ? 175.069 65.188 -78.109 1.00 20.80 ? 161 PHE B O 1 ATOM 4716 C CB . PHE B 1 153 ? 175.734 67.978 -78.945 1.00 19.31 ? 161 PHE B CB 1 ATOM 4717 C CG . PHE B 1 153 ? 176.522 68.764 -77.955 1.00 20.23 ? 161 PHE B CG 1 ATOM 4718 C CD1 . PHE B 1 153 ? 177.670 69.451 -78.359 1.00 20.29 ? 161 PHE B CD1 1 ATOM 4719 C CD2 . PHE B 1 153 ? 176.180 68.753 -76.604 1.00 21.01 ? 161 PHE B CD2 1 ATOM 4720 C CE1 . PHE B 1 153 ? 178.470 70.114 -77.427 1.00 20.23 ? 161 PHE B CE1 1 ATOM 4721 C CE2 . PHE B 1 153 ? 176.972 69.412 -75.663 1.00 19.87 ? 161 PHE B CE2 1 ATOM 4722 C CZ . PHE B 1 153 ? 178.119 70.092 -76.078 1.00 21.07 ? 161 PHE B CZ 1 ATOM 4723 N N . VAL B 1 154 ? 177.277 65.180 -77.723 1.00 21.74 ? 162 VAL B N 1 ATOM 4724 C CA . VAL B 1 154 ? 177.199 64.073 -76.806 1.00 22.29 ? 162 VAL B CA 1 ATOM 4725 C C . VAL B 1 154 ? 176.995 64.391 -75.310 1.00 22.88 ? 162 VAL B C 1 ATOM 4726 O O . VAL B 1 154 ? 177.143 63.512 -74.451 1.00 23.23 ? 162 VAL B O 1 ATOM 4727 C CB . VAL B 1 154 ? 178.441 63.167 -77.096 1.00 22.33 ? 162 VAL B CB 1 ATOM 4728 C CG1 . VAL B 1 154 ? 179.602 63.495 -76.169 1.00 21.65 ? 162 VAL B CG1 1 ATOM 4729 C CG2 . VAL B 1 154 ? 178.039 61.733 -77.078 1.00 23.12 ? 162 VAL B CG2 1 ATOM 4730 N N . GLY B 1 155 ? 176.636 65.636 -74.990 1.00 22.96 ? 163 GLY B N 1 ATOM 4731 C CA . GLY B 1 155 ? 176.386 65.972 -73.590 1.00 23.24 ? 163 GLY B CA 1 ATOM 4732 C C . GLY B 1 155 ? 177.236 67.033 -72.903 1.00 23.00 ? 163 GLY B C 1 ATOM 4733 O O . GLY B 1 155 ? 178.361 67.302 -73.319 1.00 24.75 ? 163 GLY B O 1 ATOM 4734 N N . ASP B 1 156 ? 176.693 67.612 -71.829 1.00 21.61 ? 164 ASP B N 1 ATOM 4735 C CA . ASP B 1 156 ? 177.355 68.660 -71.045 1.00 20.88 ? 164 ASP B CA 1 ATOM 4736 C C . ASP B 1 156 ? 177.582 69.866 -71.937 1.00 21.31 ? 164 ASP B C 1 ATOM 4737 O O . ASP B 1 156 ? 178.639 70.007 -72.561 1.00 21.60 ? 164 ASP B O 1 ATOM 4738 C CB . ASP B 1 156 ? 178.686 68.160 -70.462 1.00 21.02 ? 164 ASP B CB 1 ATOM 4739 C CG . ASP B 1 156 ? 178.491 67.179 -69.306 1.00 20.21 ? 164 ASP B CG 1 ATOM 4740 O OD1 . ASP B 1 156 ? 177.362 67.065 -68.787 1.00 18.35 ? 164 ASP B OD1 1 ATOM 4741 O OD2 . ASP B 1 156 ? 179.470 66.525 -68.902 1.00 22.38 ? 164 ASP B OD2 1 ATOM 4742 N N . LEU B 1 157 ? 176.577 70.735 -71.988 1.00 20.80 ? 165 LEU B N 1 ATOM 4743 C CA . LEU B 1 157 ? 176.621 71.919 -72.832 1.00 19.78 ? 165 LEU B CA 1 ATOM 4744 C C . LEU B 1 157 ? 177.358 73.134 -72.277 1.00 19.95 ? 165 LEU B C 1 ATOM 4745 O O . LEU B 1 157 ? 178.508 73.394 -72.640 1.00 20.34 ? 165 LEU B O 1 ATOM 4746 C CB . LEU B 1 157 ? 175.196 72.343 -73.219 1.00 19.31 ? 165 LEU B CB 1 ATOM 4747 C CG . LEU B 1 157 ? 174.413 71.450 -74.184 1.00 18.84 ? 165 LEU B CG 1 ATOM 4748 C CD1 . LEU B 1 157 ? 174.198 70.086 -73.560 1.00 19.94 ? 165 LEU B CD1 1 ATOM 4749 C CD2 . LEU B 1 157 ? 173.082 72.099 -74.525 1.00 18.10 ? 165 LEU B CD2 1 ATOM 4750 N N . SER B 1 158 ? 176.689 73.868 -71.395 1.00 18.22 ? 166 SER B N 1 ATOM 4751 C CA . SER B 1 158 ? 177.222 75.102 -70.826 1.00 16.84 ? 166 SER B CA 1 ATOM 4752 C C . SER B 1 158 ? 178.020 75.017 -69.531 1.00 16.76 ? 166 SER B C 1 ATOM 4753 O O . SER B 1 158 ? 178.835 75.893 -69.256 1.00 16.93 ? 166 SER B O 1 ATOM 4754 C CB . SER B 1 158 ? 176.068 76.073 -70.591 1.00 15.83 ? 166 SER B CB 1 ATOM 4755 O OG . SER B 1 158 ? 175.318 75.669 -69.458 1.00 14.53 ? 166 SER B OG 1 ATOM 4756 N N . TYR B 1 159 ? 177.773 73.989 -68.730 1.00 15.98 ? 167 TYR B N 1 ATOM 4757 C CA . TYR B 1 159 ? 178.443 73.843 -67.438 1.00 17.75 ? 167 TYR B CA 1 ATOM 4758 C C . TYR B 1 159 ? 178.058 74.979 -66.491 1.00 19.19 ? 167 TYR B C 1 ATOM 4759 O O . TYR B 1 159 ? 178.751 75.243 -65.508 1.00 20.99 ? 167 TYR B O 1 ATOM 4760 C CB . TYR B 1 159 ? 179.972 73.795 -67.585 1.00 14.82 ? 167 TYR B CB 1 ATOM 4761 C CG . TYR B 1 159 ? 180.490 72.441 -68.015 1.00 15.99 ? 167 TYR B CG 1 ATOM 4762 C CD1 . TYR B 1 159 ? 180.431 72.041 -69.351 1.00 16.01 ? 167 TYR B CD1 1 ATOM 4763 C CD2 . TYR B 1 159 ? 180.977 71.527 -67.075 1.00 15.37 ? 167 TYR B CD2 1 ATOM 4764 C CE1 . TYR B 1 159 ? 180.835 70.766 -69.745 1.00 14.68 ? 167 TYR B CE1 1 ATOM 4765 C CE2 . TYR B 1 159 ? 181.385 70.244 -67.459 1.00 14.52 ? 167 TYR B CE2 1 ATOM 4766 C CZ . TYR B 1 159 ? 181.309 69.870 -68.796 1.00 14.40 ? 167 TYR B CZ 1 ATOM 4767 O OH . TYR B 1 159 ? 181.689 68.605 -69.190 1.00 13.05 ? 167 TYR B OH 1 ATOM 4768 N N . ALA B 1 160 ? 176.944 75.644 -66.776 1.00 19.38 ? 168 ALA B N 1 ATOM 4769 C CA . ALA B 1 160 ? 176.496 76.739 -65.923 1.00 19.55 ? 168 ALA B CA 1 ATOM 4770 C C . ALA B 1 160 ? 176.242 76.298 -64.484 1.00 19.52 ? 168 ALA B C 1 ATOM 4771 O O . ALA B 1 160 ? 176.172 77.127 -63.586 1.00 21.21 ? 168 ALA B O 1 ATOM 4772 C CB . ALA B 1 160 ? 175.225 77.376 -66.504 1.00 19.45 ? 168 ALA B CB 1 ATOM 4773 N N . ASP B 1 161 ? 176.116 74.998 -64.252 1.00 21.19 ? 169 ASP B N 1 ATOM 4774 C CA . ASP B 1 161 ? 175.836 74.522 -62.901 1.00 22.12 ? 169 ASP B CA 1 ATOM 4775 C C . ASP B 1 161 ? 177.054 74.575 -62.003 1.00 23.40 ? 169 ASP B C 1 ATOM 4776 O O . ASP B 1 161 ? 176.974 74.191 -60.841 1.00 24.34 ? 169 ASP B O 1 ATOM 4777 C CB . ASP B 1 161 ? 175.276 73.098 -62.935 1.00 21.65 ? 169 ASP B CB 1 ATOM 4778 C CG . ASP B 1 161 ? 176.268 72.092 -63.489 1.00 24.09 ? 169 ASP B CG 1 ATOM 4779 O OD1 . ASP B 1 161 ? 177.044 72.461 -64.397 1.00 26.90 ? 169 ASP B OD1 1 ATOM 4780 O OD2 . ASP B 1 161 ? 176.269 70.930 -63.030 1.00 22.93 ? 169 ASP B OD2 1 ATOM 4781 N N . ARG B 1 162 ? 178.185 75.042 -62.526 1.00 24.64 ? 170 ARG B N 1 ATOM 4782 C CA . ARG B 1 162 ? 179.391 75.141 -61.703 1.00 26.00 ? 170 ARG B CA 1 ATOM 4783 C C . ARG B 1 162 ? 179.434 76.491 -61.007 1.00 26.88 ? 170 ARG B C 1 ATOM 4784 O O . ARG B 1 162 ? 180.195 76.691 -60.063 1.00 28.23 ? 170 ARG B O 1 ATOM 4785 C CB . ARG B 1 162 ? 180.658 74.952 -62.539 1.00 26.86 ? 170 ARG B CB 1 ATOM 4786 C CG . ARG B 1 162 ? 180.814 73.556 -63.091 1.00 30.23 ? 170 ARG B CG 1 ATOM 4787 C CD . ARG B 1 162 ? 182.172 73.339 -63.760 1.00 34.50 ? 170 ARG B CD 1 ATOM 4788 N NE . ARG B 1 162 ? 183.271 73.233 -62.801 1.00 37.42 ? 170 ARG B NE 1 ATOM 4789 C CZ . ARG B 1 162 ? 184.046 74.249 -62.432 1.00 38.85 ? 170 ARG B CZ 1 ATOM 4790 N NH1 . ARG B 1 162 ? 183.848 75.464 -62.941 1.00 39.29 ? 170 ARG B NH1 1 ATOM 4791 N NH2 . ARG B 1 162 ? 185.023 74.048 -61.555 1.00 38.43 ? 170 ARG B NH2 1 ATOM 4792 N N . TYR B 1 163 ? 178.612 77.421 -61.478 1.00 27.81 ? 171 TYR B N 1 ATOM 4793 C CA . TYR B 1 163 ? 178.556 78.740 -60.875 1.00 28.36 ? 171 TYR B CA 1 ATOM 4794 C C . TYR B 1 163 ? 177.569 78.716 -59.716 1.00 29.61 ? 171 TYR B C 1 ATOM 4795 O O . TYR B 1 163 ? 176.765 77.791 -59.591 1.00 30.09 ? 171 TYR B O 1 ATOM 4796 C CB . TYR B 1 163 ? 178.145 79.777 -61.921 1.00 29.45 ? 171 TYR B CB 1 ATOM 4797 C CG . TYR B 1 163 ? 179.194 79.977 -62.994 1.00 32.53 ? 171 TYR B CG 1 ATOM 4798 C CD1 . TYR B 1 163 ? 179.433 78.996 -63.954 1.00 33.55 ? 171 TYR B CD1 1 ATOM 4799 C CD2 . TYR B 1 163 ? 179.987 81.127 -63.018 1.00 34.55 ? 171 TYR B CD2 1 ATOM 4800 C CE1 . TYR B 1 163 ? 180.436 79.147 -64.910 1.00 35.02 ? 171 TYR B CE1 1 ATOM 4801 C CE2 . TYR B 1 163 ? 180.997 81.290 -63.973 1.00 36.12 ? 171 TYR B CE2 1 ATOM 4802 C CZ . TYR B 1 163 ? 181.216 80.296 -64.912 1.00 36.31 ? 171 TYR B CZ 1 ATOM 4803 O OH . TYR B 1 163 ? 182.221 80.445 -65.845 1.00 38.33 ? 171 TYR B OH 1 ATOM 4804 N N . PRO B 1 164 ? 177.636 79.718 -58.829 1.00 29.93 ? 172 PRO B N 1 ATOM 4805 C CA . PRO B 1 164 ? 176.720 79.772 -57.684 1.00 28.30 ? 172 PRO B CA 1 ATOM 4806 C C . PRO B 1 164 ? 175.256 79.896 -58.114 1.00 27.00 ? 172 PRO B C 1 ATOM 4807 O O . PRO B 1 164 ? 174.910 80.767 -58.907 1.00 26.42 ? 172 PRO B O 1 ATOM 4808 C CB . PRO B 1 164 ? 177.220 80.987 -56.903 1.00 29.52 ? 172 PRO B CB 1 ATOM 4809 C CG . PRO B 1 164 ? 177.845 81.850 -57.966 1.00 30.91 ? 172 PRO B CG 1 ATOM 4810 C CD . PRO B 1 164 ? 178.583 80.845 -58.801 1.00 29.60 ? 172 PRO B CD 1 ATOM 4811 N N . ASN B 1 165 ? 174.405 79.020 -57.585 1.00 26.24 ? 173 ASN B N 1 ATOM 4812 C CA . ASN B 1 165 ? 172.985 79.018 -57.927 1.00 25.43 ? 173 ASN B CA 1 ATOM 4813 C C . ASN B 1 165 ? 172.834 78.667 -59.406 1.00 23.83 ? 173 ASN B C 1 ATOM 4814 O O . ASN B 1 165 ? 171.838 79.007 -60.037 1.00 22.23 ? 173 ASN B O 1 ATOM 4815 C CB . ASN B 1 165 ? 172.373 80.400 -57.664 1.00 28.20 ? 173 ASN B CB 1 ATOM 4816 C CG . ASN B 1 165 ? 172.330 80.760 -56.185 1.00 29.68 ? 173 ASN B CG 1 ATOM 4817 O OD1 . ASN B 1 165 ? 172.248 81.936 -55.835 1.00 32.05 ? 173 ASN B OD1 1 ATOM 4818 N ND2 . ASN B 1 165 ? 172.364 79.754 -55.314 1.00 29.84 ? 173 ASN B ND2 1 ATOM 4819 N N . HIS B 1 166 ? 173.834 77.983 -59.951 1.00 23.88 ? 174 HIS B N 1 ATOM 4820 C CA . HIS B 1 166 ? 173.849 77.592 -61.363 1.00 24.44 ? 174 HIS B CA 1 ATOM 4821 C C . HIS B 1 166 ? 173.640 78.805 -62.266 1.00 23.99 ? 174 HIS B C 1 ATOM 4822 O O . HIS B 1 166 ? 173.082 78.674 -63.350 1.00 24.10 ? 174 HIS B O 1 ATOM 4823 C CB . HIS B 1 166 ? 172.747 76.568 -61.685 1.00 25.51 ? 174 HIS B CB 1 ATOM 4824 C CG . HIS B 1 166 ? 172.782 75.326 -60.847 1.00 26.33 ? 174 HIS B CG 1 ATOM 4825 N ND1 . HIS B 1 166 ? 172.197 74.147 -61.255 1.00 26.86 ? 174 HIS B ND1 1 ATOM 4826 C CD2 . HIS B 1 166 ? 173.281 75.092 -59.609 1.00 26.64 ? 174 HIS B CD2 1 ATOM 4827 C CE1 . HIS B 1 166 ? 172.335 73.238 -60.303 1.00 28.70 ? 174 HIS B CE1 1 ATOM 4828 N NE2 . HIS B 1 166 ? 172.988 73.786 -59.294 1.00 26.65 ? 174 HIS B NE2 1 ATOM 4829 N N . ASP B 1 167 ? 174.080 79.977 -61.813 1.00 24.09 ? 175 ASP B N 1 ATOM 4830 C CA . ASP B 1 167 ? 173.940 81.227 -62.566 1.00 23.71 ? 175 ASP B CA 1 ATOM 4831 C C . ASP B 1 167 ? 173.496 81.005 -64.005 1.00 22.71 ? 175 ASP B C 1 ATOM 4832 O O . ASP B 1 167 ? 174.334 80.854 -64.893 1.00 22.16 ? 175 ASP B O 1 ATOM 4833 C CB . ASP B 1 167 ? 175.266 81.986 -62.583 1.00 25.27 ? 175 ASP B CB 1 ATOM 4834 C CG . ASP B 1 167 ? 175.081 83.468 -62.862 1.00 27.85 ? 175 ASP B CG 1 ATOM 4835 O OD1 . ASP B 1 167 ? 174.089 83.836 -63.529 1.00 28.60 ? 175 ASP B OD1 1 ATOM 4836 O OD2 . ASP B 1 167 ? 175.931 84.267 -62.417 1.00 30.17 ? 175 ASP B OD2 1 ATOM 4837 N N . ASN B 1 168 ? 172.188 80.995 -64.248 1.00 22.34 ? 176 ASN B N 1 ATOM 4838 C CA . ASN B 1 168 ? 171.704 80.764 -65.603 1.00 21.99 ? 176 ASN B CA 1 ATOM 4839 C C . ASN B 1 168 ? 172.165 81.779 -66.640 1.00 21.91 ? 176 ASN B C 1 ATOM 4840 O O . ASN B 1 168 ? 171.899 81.617 -67.831 1.00 21.83 ? 176 ASN B O 1 ATOM 4841 C CB . ASN B 1 168 ? 170.181 80.644 -65.632 1.00 22.37 ? 176 ASN B CB 1 ATOM 4842 C CG . ASN B 1 168 ? 169.709 79.230 -65.344 1.00 24.13 ? 176 ASN B CG 1 ATOM 4843 O OD1 . ASN B 1 168 ? 168.664 78.796 -65.834 1.00 25.78 ? 176 ASN B OD1 1 ATOM 4844 N ND2 . ASN B 1 168 ? 170.476 78.503 -64.542 1.00 24.13 ? 176 ASN B ND2 1 ATOM 4845 N N . VAL B 1 169 ? 172.851 82.828 -66.206 1.00 21.71 ? 177 VAL B N 1 ATOM 4846 C CA . VAL B 1 169 ? 173.348 83.803 -67.162 1.00 21.79 ? 177 VAL B CA 1 ATOM 4847 C C . VAL B 1 169 ? 174.361 83.062 -68.040 1.00 21.91 ? 177 VAL B C 1 ATOM 4848 O O . VAL B 1 169 ? 174.503 83.355 -69.234 1.00 22.00 ? 177 VAL B O 1 ATOM 4849 C CB . VAL B 1 169 ? 174.019 85.005 -66.449 1.00 21.46 ? 177 VAL B CB 1 ATOM 4850 C CG1 . VAL B 1 169 ? 174.808 85.846 -67.446 1.00 21.85 ? 177 VAL B CG1 1 ATOM 4851 C CG2 . VAL B 1 169 ? 172.953 85.863 -65.794 1.00 20.56 ? 177 VAL B CG2 1 ATOM 4852 N N . ARG B 1 170 ? 175.040 82.083 -67.446 1.00 21.04 ? 178 ARG B N 1 ATOM 4853 C CA . ARG B 1 170 ? 176.020 81.284 -68.164 1.00 21.29 ? 178 ARG B CA 1 ATOM 4854 C C . ARG B 1 170 ? 175.392 80.399 -69.237 1.00 22.10 ? 178 ARG B C 1 ATOM 4855 O O . ARG B 1 170 ? 176.098 79.875 -70.101 1.00 23.58 ? 178 ARG B O 1 ATOM 4856 C CB . ARG B 1 170 ? 176.828 80.439 -67.184 1.00 22.62 ? 178 ARG B CB 1 ATOM 4857 C CG . ARG B 1 170 ? 177.945 81.218 -66.495 1.00 23.16 ? 178 ARG B CG 1 ATOM 4858 C CD . ARG B 1 170 ? 178.962 81.742 -67.512 1.00 22.86 ? 178 ARG B CD 1 ATOM 4859 N NE . ARG B 1 170 ? 179.975 82.580 -66.873 1.00 23.77 ? 178 ARG B NE 1 ATOM 4860 C CZ . ARG B 1 170 ? 181.090 82.996 -67.466 1.00 23.93 ? 178 ARG B CZ 1 ATOM 4861 N NH1 . ARG B 1 170 ? 181.350 82.654 -68.721 1.00 20.23 ? 178 ARG B NH1 1 ATOM 4862 N NH2 . ARG B 1 170 ? 181.951 83.752 -66.793 1.00 26.15 ? 178 ARG B NH2 1 ATOM 4863 N N . TRP B 1 171 ? 174.072 80.222 -69.181 1.00 21.67 ? 179 TRP B N 1 ATOM 4864 C CA . TRP B 1 171 ? 173.376 79.451 -70.211 1.00 21.03 ? 179 TRP B CA 1 ATOM 4865 C C . TRP B 1 171 ? 173.189 80.403 -71.374 1.00 21.08 ? 179 TRP B C 1 ATOM 4866 O O . TRP B 1 171 ? 173.327 80.024 -72.535 1.00 21.84 ? 179 TRP B O 1 ATOM 4867 C CB . TRP B 1 171 ? 171.996 78.980 -69.747 1.00 21.11 ? 179 TRP B CB 1 ATOM 4868 C CG . TRP B 1 171 ? 171.981 77.581 -69.214 1.00 19.58 ? 179 TRP B CG 1 ATOM 4869 C CD1 . TRP B 1 171 ? 171.726 77.192 -67.927 1.00 20.06 ? 179 TRP B CD1 1 ATOM 4870 C CD2 . TRP B 1 171 ? 172.210 76.379 -69.960 1.00 18.88 ? 179 TRP B CD2 1 ATOM 4871 N NE1 . TRP B 1 171 ? 171.775 75.818 -67.831 1.00 20.08 ? 179 TRP B NE1 1 ATOM 4872 C CE2 . TRP B 1 171 ? 172.068 75.296 -69.063 1.00 20.06 ? 179 TRP B CE2 1 ATOM 4873 C CE3 . TRP B 1 171 ? 172.510 76.113 -71.301 1.00 18.48 ? 179 TRP B CE3 1 ATOM 4874 C CZ2 . TRP B 1 171 ? 172.225 73.960 -69.468 1.00 18.55 ? 179 TRP B CZ2 1 ATOM 4875 C CZ3 . TRP B 1 171 ? 172.662 74.783 -71.704 1.00 17.70 ? 179 TRP B CZ3 1 ATOM 4876 C CH2 . TRP B 1 171 ? 172.516 73.726 -70.788 1.00 17.58 ? 179 TRP B CH2 1 ATOM 4877 N N . ASP B 1 172 ? 172.873 81.652 -71.050 1.00 22.09 ? 180 ASP B N 1 ATOM 4878 C CA . ASP B 1 172 ? 172.682 82.672 -72.069 1.00 22.94 ? 180 ASP B CA 1 ATOM 4879 C C . ASP B 1 172 ? 173.979 82.922 -72.832 1.00 23.60 ? 180 ASP B C 1 ATOM 4880 O O . ASP B 1 172 ? 173.980 82.899 -74.063 1.00 25.18 ? 180 ASP B O 1 ATOM 4881 C CB . ASP B 1 172 ? 172.198 83.989 -71.444 1.00 22.41 ? 180 ASP B CB 1 ATOM 4882 C CG . ASP B 1 172 ? 170.799 83.888 -70.869 1.00 22.22 ? 180 ASP B CG 1 ATOM 4883 O OD1 . ASP B 1 172 ? 169.876 83.477 -71.610 1.00 22.23 ? 180 ASP B OD1 1 ATOM 4884 O OD2 . ASP B 1 172 ? 170.627 84.225 -69.678 1.00 20.02 ? 180 ASP B OD2 1 ATOM 4885 N N . THR B 1 173 ? 175.080 83.160 -72.117 1.00 22.95 ? 181 THR B N 1 ATOM 4886 C CA . THR B 1 173 ? 176.355 83.408 -72.791 1.00 22.74 ? 181 THR B CA 1 ATOM 4887 C C . THR B 1 173 ? 176.703 82.261 -73.747 1.00 23.14 ? 181 THR B C 1 ATOM 4888 O O . THR B 1 173 ? 177.131 82.495 -74.889 1.00 24.07 ? 181 THR B O 1 ATOM 4889 C CB . THR B 1 173 ? 177.525 83.611 -71.781 1.00 22.69 ? 181 THR B CB 1 ATOM 4890 O OG1 . THR B 1 173 ? 177.601 82.495 -70.886 1.00 20.66 ? 181 THR B OG1 1 ATOM 4891 C CG2 . THR B 1 173 ? 177.323 84.887 -70.986 1.00 22.27 ? 181 THR B CG2 1 ATOM 4892 N N . TRP B 1 174 ? 176.511 81.027 -73.281 1.00 23.16 ? 182 TRP B N 1 ATOM 4893 C CA . TRP B 1 174 ? 176.793 79.839 -74.088 1.00 21.90 ? 182 TRP B CA 1 ATOM 4894 C C . TRP B 1 174 ? 175.907 79.824 -75.334 1.00 21.62 ? 182 TRP B C 1 ATOM 4895 O O . TRP B 1 174 ? 176.264 79.256 -76.369 1.00 21.99 ? 182 TRP B O 1 ATOM 4896 C CB . TRP B 1 174 ? 176.532 78.575 -73.275 1.00 22.59 ? 182 TRP B CB 1 ATOM 4897 C CG . TRP B 1 174 ? 177.155 77.345 -73.865 1.00 23.20 ? 182 TRP B CG 1 ATOM 4898 C CD1 . TRP B 1 174 ? 178.442 76.917 -73.689 1.00 23.93 ? 182 TRP B CD1 1 ATOM 4899 C CD2 . TRP B 1 174 ? 176.525 76.379 -74.723 1.00 22.58 ? 182 TRP B CD2 1 ATOM 4900 N NE1 . TRP B 1 174 ? 178.651 75.745 -74.380 1.00 24.36 ? 182 TRP B NE1 1 ATOM 4901 C CE2 . TRP B 1 174 ? 177.493 75.394 -75.023 1.00 23.38 ? 182 TRP B CE2 1 ATOM 4902 C CE3 . TRP B 1 174 ? 175.239 76.252 -75.268 1.00 22.02 ? 182 TRP B CE3 1 ATOM 4903 C CZ2 . TRP B 1 174 ? 177.215 74.293 -75.842 1.00 23.43 ? 182 TRP B CZ2 1 ATOM 4904 C CZ3 . TRP B 1 174 ? 174.962 75.157 -76.083 1.00 20.76 ? 182 TRP B CZ3 1 ATOM 4905 C CH2 . TRP B 1 174 ? 175.947 74.193 -76.361 1.00 23.45 ? 182 TRP B CH2 1 ATOM 4906 N N . GLY B 1 175 ? 174.743 80.448 -75.225 1.00 20.49 ? 183 GLY B N 1 ATOM 4907 C CA . GLY B 1 175 ? 173.837 80.495 -76.352 1.00 21.67 ? 183 GLY B CA 1 ATOM 4908 C C . GLY B 1 175 ? 174.356 81.409 -77.442 1.00 22.67 ? 183 GLY B C 1 ATOM 4909 O O . GLY B 1 175 ? 174.246 81.091 -78.629 1.00 23.14 ? 183 GLY B O 1 ATOM 4910 N N . ARG B 1 176 ? 174.927 82.545 -77.048 1.00 22.88 ? 184 ARG B N 1 ATOM 4911 C CA . ARG B 1 176 ? 175.461 83.496 -78.017 1.00 23.60 ? 184 ARG B CA 1 ATOM 4912 C C . ARG B 1 176 ? 176.767 82.965 -78.598 1.00 23.39 ? 184 ARG B C 1 ATOM 4913 O O . ARG B 1 176 ? 177.026 83.095 -79.796 1.00 22.23 ? 184 ARG B O 1 ATOM 4914 C CB . ARG B 1 176 ? 175.717 84.847 -77.354 1.00 25.11 ? 184 ARG B CB 1 ATOM 4915 C CG . ARG B 1 176 ? 174.514 85.466 -76.667 1.00 25.12 ? 184 ARG B CG 1 ATOM 4916 C CD . ARG B 1 176 ? 174.904 86.778 -75.994 1.00 25.22 ? 184 ARG B CD 1 ATOM 4917 N NE . ARG B 1 176 ? 174.035 87.056 -74.861 1.00 25.23 ? 184 ARG B NE 1 ATOM 4918 C CZ . ARG B 1 176 ? 174.469 87.391 -73.654 1.00 24.84 ? 184 ARG B CZ 1 ATOM 4919 N NH1 . ARG B 1 176 ? 175.769 87.495 -73.418 1.00 24.66 ? 184 ARG B NH1 1 ATOM 4920 N NH2 . ARG B 1 176 ? 173.601 87.604 -72.675 1.00 29.20 ? 184 ARG B NH2 1 ATOM 4921 N N . PHE B 1 177 ? 177.578 82.373 -77.726 1.00 22.74 ? 185 PHE B N 1 ATOM 4922 C CA . PHE B 1 177 ? 178.868 81.793 -78.089 1.00 23.11 ? 185 PHE B CA 1 ATOM 4923 C C . PHE B 1 177 ? 178.776 80.757 -79.209 1.00 24.26 ? 185 PHE B C 1 ATOM 4924 O O . PHE B 1 177 ? 179.517 80.824 -80.195 1.00 26.77 ? 185 PHE B O 1 ATOM 4925 C CB . PHE B 1 177 ? 179.500 81.155 -76.842 1.00 23.27 ? 185 PHE B CB 1 ATOM 4926 C CG . PHE B 1 177 ? 180.594 80.156 -77.138 1.00 23.93 ? 185 PHE B CG 1 ATOM 4927 C CD1 . PHE B 1 177 ? 181.676 80.492 -77.946 1.00 25.14 ? 185 PHE B CD1 1 ATOM 4928 C CD2 . PHE B 1 177 ? 180.557 78.887 -76.572 1.00 23.75 ? 185 PHE B CD2 1 ATOM 4929 C CE1 . PHE B 1 177 ? 182.707 79.577 -78.185 1.00 25.31 ? 185 PHE B CE1 1 ATOM 4930 C CE2 . PHE B 1 177 ? 181.578 77.966 -76.803 1.00 23.69 ? 185 PHE B CE2 1 ATOM 4931 C CZ . PHE B 1 177 ? 182.656 78.311 -77.609 1.00 24.16 ? 185 PHE B CZ 1 ATOM 4932 N N . THR B 1 178 ? 177.861 79.806 -79.055 1.00 22.89 ? 186 THR B N 1 ATOM 4933 C CA . THR B 1 178 ? 177.696 78.743 -80.032 1.00 21.79 ? 186 THR B CA 1 ATOM 4934 C C . THR B 1 178 ? 176.838 79.124 -81.233 1.00 22.80 ? 186 THR B C 1 ATOM 4935 O O . THR B 1 178 ? 176.832 78.406 -82.239 1.00 22.87 ? 186 THR B O 1 ATOM 4936 C CB . THR B 1 178 ? 177.093 77.470 -79.371 1.00 20.88 ? 186 THR B CB 1 ATOM 4937 O OG1 . THR B 1 178 ? 175.876 77.813 -78.696 1.00 21.46 ? 186 THR B OG1 1 ATOM 4938 C CG2 . THR B 1 178 ? 178.067 76.866 -78.361 1.00 17.41 ? 186 THR B CG2 1 ATOM 4939 N N . GLU B 1 179 ? 176.124 80.246 -81.145 1.00 22.64 ? 187 GLU B N 1 ATOM 4940 C CA . GLU B 1 179 ? 175.261 80.679 -82.249 1.00 23.12 ? 187 GLU B CA 1 ATOM 4941 C C . GLU B 1 179 ? 175.951 80.662 -83.610 1.00 24.01 ? 187 GLU B C 1 ATOM 4942 O O . GLU B 1 179 ? 175.361 80.241 -84.608 1.00 23.99 ? 187 GLU B O 1 ATOM 4943 C CB . GLU B 1 179 ? 174.715 82.094 -82.002 1.00 21.74 ? 187 GLU B CB 1 ATOM 4944 C CG . GLU B 1 179 ? 173.631 82.515 -83.005 1.00 21.86 ? 187 GLU B CG 1 ATOM 4945 C CD . GLU B 1 179 ? 173.177 83.960 -82.818 1.00 24.33 ? 187 GLU B CD 1 ATOM 4946 O OE1 . GLU B 1 179 ? 173.907 84.873 -83.245 1.00 25.22 ? 187 GLU B OE1 1 ATOM 4947 O OE2 . GLU B 1 179 ? 172.094 84.192 -82.241 1.00 23.13 ? 187 GLU B OE2 1 ATOM 4948 N N . ARG B 1 180 ? 177.201 81.116 -83.648 1.00 24.91 ? 188 ARG B N 1 ATOM 4949 C CA . ARG B 1 180 ? 177.941 81.193 -84.902 1.00 25.06 ? 188 ARG B CA 1 ATOM 4950 C C . ARG B 1 180 ? 177.941 79.888 -85.693 1.00 24.61 ? 188 ARG B C 1 ATOM 4951 O O . ARG B 1 180 ? 178.272 79.876 -86.876 1.00 24.33 ? 188 ARG B O 1 ATOM 4952 C CB . ARG B 1 180 ? 179.377 81.669 -84.633 1.00 26.47 ? 188 ARG B CB 1 ATOM 4953 C CG . ARG B 1 180 ? 180.342 80.606 -84.151 1.00 28.56 ? 188 ARG B CG 1 ATOM 4954 C CD . ARG B 1 180 ? 181.511 81.249 -83.403 1.00 30.91 ? 188 ARG B CD 1 ATOM 4955 N NE . ARG B 1 180 ? 182.804 80.634 -83.707 1.00 30.49 ? 188 ARG B NE 1 ATOM 4956 C CZ . ARG B 1 180 ? 183.818 80.550 -82.846 1.00 29.48 ? 188 ARG B CZ 1 ATOM 4957 N NH1 . ARG B 1 180 ? 183.700 81.033 -81.615 1.00 26.96 ? 188 ARG B NH1 1 ATOM 4958 N NH2 . ARG B 1 180 ? 184.958 79.988 -83.221 1.00 30.09 ? 188 ARG B NH2 1 ATOM 4959 N N . SER B 1 181 ? 177.543 78.795 -85.049 1.00 23.81 ? 189 SER B N 1 ATOM 4960 C CA . SER B 1 181 ? 177.507 77.496 -85.709 1.00 22.25 ? 189 SER B CA 1 ATOM 4961 C C . SER B 1 181 ? 176.119 76.865 -85.728 1.00 22.68 ? 189 SER B C 1 ATOM 4962 O O . SER B 1 181 ? 175.604 76.517 -86.791 1.00 23.21 ? 189 SER B O 1 ATOM 4963 C CB . SER B 1 181 ? 178.491 76.534 -85.028 1.00 22.24 ? 189 SER B CB 1 ATOM 4964 O OG . SER B 1 181 ? 178.446 75.244 -85.615 1.00 19.88 ? 189 SER B OG 1 ATOM 4965 N N . VAL B 1 182 ? 175.520 76.721 -84.551 1.00 22.70 ? 190 VAL B N 1 ATOM 4966 C CA . VAL B 1 182 ? 174.209 76.100 -84.419 1.00 22.60 ? 190 VAL B CA 1 ATOM 4967 C C . VAL B 1 182 ? 173.077 76.868 -85.101 1.00 23.15 ? 190 VAL B C 1 ATOM 4968 O O . VAL B 1 182 ? 171.945 76.377 -85.182 1.00 24.17 ? 190 VAL B O 1 ATOM 4969 C CB . VAL B 1 182 ? 173.831 75.922 -82.944 1.00 22.03 ? 190 VAL B CB 1 ATOM 4970 C CG1 . VAL B 1 182 ? 172.989 74.661 -82.783 1.00 22.20 ? 190 VAL B CG1 1 ATOM 4971 C CG2 . VAL B 1 182 ? 175.072 75.856 -82.092 1.00 24.49 ? 190 VAL B CG2 1 ATOM 4972 N N . ALA B 1 183 ? 173.369 78.068 -85.586 1.00 22.08 ? 191 ALA B N 1 ATOM 4973 C CA . ALA B 1 183 ? 172.346 78.868 -86.251 1.00 22.24 ? 191 ALA B CA 1 ATOM 4974 C C . ALA B 1 183 ? 172.325 78.558 -87.737 1.00 23.03 ? 191 ALA B C 1 ATOM 4975 O O . ALA B 1 183 ? 171.324 78.796 -88.413 1.00 23.71 ? 191 ALA B O 1 ATOM 4976 C CB . ALA B 1 183 ? 172.611 80.363 -86.035 1.00 20.22 ? 191 ALA B CB 1 ATOM 4977 N N . TYR B 1 184 ? 173.431 78.013 -88.237 1.00 23.33 ? 192 TYR B N 1 ATOM 4978 C CA . TYR B 1 184 ? 173.565 77.693 -89.655 1.00 23.58 ? 192 TYR B CA 1 ATOM 4979 C C . TYR B 1 184 ? 173.479 76.205 -89.985 1.00 24.46 ? 192 TYR B C 1 ATOM 4980 O O . TYR B 1 184 ? 173.137 75.835 -91.106 1.00 24.72 ? 192 TYR B O 1 ATOM 4981 C CB . TYR B 1 184 ? 174.880 78.270 -90.167 1.00 23.91 ? 192 TYR B CB 1 ATOM 4982 C CG . TYR B 1 184 ? 174.938 79.773 -90.048 1.00 24.81 ? 192 TYR B CG 1 ATOM 4983 C CD1 . TYR B 1 184 ? 174.377 80.596 -91.032 1.00 24.56 ? 192 TYR B CD1 1 ATOM 4984 C CD2 . TYR B 1 184 ? 175.505 80.376 -88.929 1.00 24.67 ? 192 TYR B CD2 1 ATOM 4985 C CE1 . TYR B 1 184 ? 174.379 81.978 -90.901 1.00 25.54 ? 192 TYR B CE1 1 ATOM 4986 C CE2 . TYR B 1 184 ? 175.508 81.763 -88.785 1.00 26.95 ? 192 TYR B CE2 1 ATOM 4987 C CZ . TYR B 1 184 ? 174.944 82.557 -89.774 1.00 26.36 ? 192 TYR B CZ 1 ATOM 4988 O OH . TYR B 1 184 ? 174.941 83.927 -89.630 1.00 29.56 ? 192 TYR B OH 1 ATOM 4989 N N . GLN B 1 185 ? 173.804 75.351 -89.020 1.00 24.85 ? 193 GLN B N 1 ATOM 4990 C CA . GLN B 1 185 ? 173.722 73.911 -89.232 1.00 23.44 ? 193 GLN B CA 1 ATOM 4991 C C . GLN B 1 185 ? 173.194 73.271 -87.948 1.00 23.35 ? 193 GLN B C 1 ATOM 4992 O O . GLN B 1 185 ? 173.554 73.676 -86.841 1.00 23.84 ? 193 GLN B O 1 ATOM 4993 C CB . GLN B 1 185 ? 175.095 73.337 -89.600 1.00 23.12 ? 193 GLN B CB 1 ATOM 4994 C CG . GLN B 1 185 ? 176.015 73.064 -88.429 1.00 24.68 ? 193 GLN B CG 1 ATOM 4995 C CD . GLN B 1 185 ? 177.273 72.335 -88.858 1.00 26.20 ? 193 GLN B CD 1 ATOM 4996 O OE1 . GLN B 1 185 ? 177.792 71.476 -88.138 1.00 26.38 ? 193 GLN B OE1 1 ATOM 4997 N NE2 . GLN B 1 185 ? 177.778 72.683 -90.032 1.00 25.81 ? 193 GLN B NE2 1 ATOM 4998 N N . PRO B 1 186 ? 172.326 72.264 -88.077 1.00 21.78 ? 194 PRO B N 1 ATOM 4999 C CA . PRO B 1 186 ? 171.768 71.600 -86.898 1.00 21.60 ? 194 PRO B CA 1 ATOM 5000 C C . PRO B 1 186 ? 172.764 70.871 -85.993 1.00 21.62 ? 194 PRO B C 1 ATOM 5001 O O . PRO B 1 186 ? 173.815 70.400 -86.435 1.00 22.37 ? 194 PRO B O 1 ATOM 5002 C CB . PRO B 1 186 ? 170.749 70.642 -87.505 1.00 20.72 ? 194 PRO B CB 1 ATOM 5003 C CG . PRO B 1 186 ? 171.397 70.273 -88.800 1.00 20.97 ? 194 PRO B CG 1 ATOM 5004 C CD . PRO B 1 186 ? 171.866 71.612 -89.312 1.00 20.88 ? 194 PRO B CD 1 ATOM 5005 N N . TRP B 1 187 ? 172.413 70.805 -84.715 1.00 20.40 ? 195 TRP B N 1 ATOM 5006 C CA . TRP B 1 187 ? 173.186 70.095 -83.709 1.00 19.47 ? 195 TRP B CA 1 ATOM 5007 C C . TRP B 1 187 ? 172.167 69.147 -83.081 1.00 19.53 ? 195 TRP B C 1 ATOM 5008 O O . TRP B 1 187 ? 171.042 69.551 -82.785 1.00 18.84 ? 195 TRP B O 1 ATOM 5009 C CB . TRP B 1 187 ? 173.720 71.050 -82.645 1.00 19.19 ? 195 TRP B CB 1 ATOM 5010 C CG . TRP B 1 187 ? 174.932 71.840 -83.051 1.00 20.47 ? 195 TRP B CG 1 ATOM 5011 C CD1 . TRP B 1 187 ? 175.175 72.406 -84.271 1.00 20.73 ? 195 TRP B CD1 1 ATOM 5012 C CD2 . TRP B 1 187 ? 176.037 72.214 -82.210 1.00 20.72 ? 195 TRP B CD2 1 ATOM 5013 N NE1 . TRP B 1 187 ? 176.356 73.109 -84.243 1.00 19.66 ? 195 TRP B NE1 1 ATOM 5014 C CE2 . TRP B 1 187 ? 176.907 73.009 -82.993 1.00 19.05 ? 195 TRP B CE2 1 ATOM 5015 C CE3 . TRP B 1 187 ? 176.376 71.957 -80.871 1.00 20.78 ? 195 TRP B CE3 1 ATOM 5016 C CZ2 . TRP B 1 187 ? 178.094 73.552 -82.482 1.00 18.73 ? 195 TRP B CZ2 1 ATOM 5017 C CZ3 . TRP B 1 187 ? 177.562 72.499 -80.361 1.00 20.57 ? 195 TRP B CZ3 1 ATOM 5018 C CH2 . TRP B 1 187 ? 178.404 73.287 -81.170 1.00 19.66 ? 195 TRP B CH2 1 ATOM 5019 N N . ILE B 1 188 ? 172.550 67.887 -82.912 1.00 19.77 ? 196 ILE B N 1 ATOM 5020 C CA . ILE B 1 188 ? 171.667 66.882 -82.329 1.00 20.07 ? 196 ILE B CA 1 ATOM 5021 C C . ILE B 1 188 ? 171.979 66.824 -80.849 1.00 19.99 ? 196 ILE B C 1 ATOM 5022 O O . ILE B 1 188 ? 173.081 66.457 -80.467 1.00 21.19 ? 196 ILE B O 1 ATOM 5023 C CB . ILE B 1 188 ? 171.920 65.494 -82.947 1.00 19.29 ? 196 ILE B CB 1 ATOM 5024 C CG1 . ILE B 1 188 ? 171.882 65.592 -84.475 1.00 19.26 ? 196 ILE B CG1 1 ATOM 5025 C CG2 . ILE B 1 188 ? 170.909 64.503 -82.413 1.00 18.77 ? 196 ILE B CG2 1 ATOM 5026 C CD1 . ILE B 1 188 ? 170.708 66.390 -85.020 1.00 17.76 ? 196 ILE B CD1 1 ATOM 5027 N N . TRP B 1 189 ? 171.006 67.156 -80.012 1.00 19.50 ? 197 TRP B N 1 ATOM 5028 C CA . TRP B 1 189 ? 171.244 67.185 -78.572 1.00 18.13 ? 197 TRP B CA 1 ATOM 5029 C C . TRP B 1 189 ? 171.129 65.880 -77.789 1.00 17.14 ? 197 TRP B C 1 ATOM 5030 O O . TRP B 1 189 ? 170.237 65.065 -78.028 1.00 18.62 ? 197 TRP B O 1 ATOM 5031 C CB . TRP B 1 189 ? 170.331 68.228 -77.929 1.00 17.15 ? 197 TRP B CB 1 ATOM 5032 C CG . TRP B 1 189 ? 170.403 69.560 -78.599 1.00 17.36 ? 197 TRP B CG 1 ATOM 5033 C CD1 . TRP B 1 189 ? 169.414 70.171 -79.316 1.00 15.83 ? 197 TRP B CD1 1 ATOM 5034 C CD2 . TRP B 1 189 ? 171.524 70.453 -78.616 1.00 16.42 ? 197 TRP B CD2 1 ATOM 5035 N NE1 . TRP B 1 189 ? 169.848 71.391 -79.774 1.00 16.59 ? 197 TRP B NE1 1 ATOM 5036 C CE2 . TRP B 1 189 ? 171.139 71.591 -79.358 1.00 15.46 ? 197 TRP B CE2 1 ATOM 5037 C CE3 . TRP B 1 189 ? 172.813 70.405 -78.073 1.00 17.48 ? 197 TRP B CE3 1 ATOM 5038 C CZ2 . TRP B 1 189 ? 171.999 72.674 -79.574 1.00 15.13 ? 197 TRP B CZ2 1 ATOM 5039 C CZ3 . TRP B 1 189 ? 173.670 71.489 -78.287 1.00 17.83 ? 197 TRP B CZ3 1 ATOM 5040 C CH2 . TRP B 1 189 ? 173.255 72.605 -79.030 1.00 15.63 ? 197 TRP B CH2 1 ATOM 5041 N N . THR B 1 190 ? 172.052 65.707 -76.849 1.00 15.31 ? 198 THR B N 1 ATOM 5042 C CA . THR B 1 190 ? 172.099 64.555 -75.956 1.00 15.33 ? 198 THR B CA 1 ATOM 5043 C C . THR B 1 190 ? 172.291 65.142 -74.560 1.00 15.50 ? 198 THR B C 1 ATOM 5044 O O . THR B 1 190 ? 173.194 65.950 -74.351 1.00 15.87 ? 198 THR B O 1 ATOM 5045 C CB . THR B 1 190 ? 173.290 63.646 -76.277 1.00 15.22 ? 198 THR B CB 1 ATOM 5046 O OG1 . THR B 1 190 ? 173.127 63.099 -77.588 1.00 15.93 ? 198 THR B OG1 1 ATOM 5047 C CG2 . THR B 1 190 ? 173.379 62.511 -75.272 1.00 14.75 ? 198 THR B CG2 1 ATOM 5048 N N . ALA B 1 191 ? 171.454 64.746 -73.606 1.00 14.92 ? 199 ALA B N 1 ATOM 5049 C CA . ALA B 1 191 ? 171.555 65.287 -72.253 1.00 15.59 ? 199 ALA B CA 1 ATOM 5050 C C . ALA B 1 191 ? 172.698 64.679 -71.452 1.00 15.83 ? 199 ALA B C 1 ATOM 5051 O O . ALA B 1 191 ? 172.875 63.464 -71.423 1.00 15.39 ? 199 ALA B O 1 ATOM 5052 C CB . ALA B 1 191 ? 170.234 65.093 -71.511 1.00 13.65 ? 199 ALA B CB 1 ATOM 5053 N N . GLY B 1 192 ? 173.468 65.543 -70.798 1.00 17.69 ? 200 GLY B N 1 ATOM 5054 C CA . GLY B 1 192 ? 174.592 65.093 -69.988 1.00 17.96 ? 200 GLY B CA 1 ATOM 5055 C C . GLY B 1 192 ? 174.335 65.326 -68.508 1.00 18.35 ? 200 GLY B C 1 ATOM 5056 O O . GLY B 1 192 ? 173.341 65.970 -68.141 1.00 18.49 ? 200 GLY B O 1 ATOM 5057 N N . ASN B 1 193 ? 175.215 64.819 -67.649 1.00 16.74 ? 201 ASN B N 1 ATOM 5058 C CA . ASN B 1 193 ? 175.004 64.990 -66.221 1.00 16.66 ? 201 ASN B CA 1 ATOM 5059 C C . ASN B 1 193 ? 174.985 66.451 -65.790 1.00 15.90 ? 201 ASN B C 1 ATOM 5060 O O . ASN B 1 193 ? 174.384 66.792 -64.782 1.00 14.64 ? 201 ASN B O 1 ATOM 5061 C CB . ASN B 1 193 ? 176.052 64.219 -65.420 1.00 18.35 ? 201 ASN B CB 1 ATOM 5062 C CG . ASN B 1 193 ? 177.447 64.771 -65.600 1.00 20.70 ? 201 ASN B CG 1 ATOM 5063 O OD1 . ASN B 1 193 ? 177.966 64.842 -66.717 1.00 22.44 ? 201 ASN B OD1 1 ATOM 5064 N ND2 . ASN B 1 193 ? 178.066 65.164 -64.496 1.00 20.74 ? 201 ASN B ND2 1 ATOM 5065 N N . HIS B 1 194 ? 175.632 67.325 -66.544 1.00 16.81 ? 202 HIS B N 1 ATOM 5066 C CA . HIS B 1 194 ? 175.625 68.731 -66.169 1.00 18.54 ? 202 HIS B CA 1 ATOM 5067 C C . HIS B 1 194 ? 174.326 69.436 -66.569 1.00 19.16 ? 202 HIS B C 1 ATOM 5068 O O . HIS B 1 194 ? 174.170 70.640 -66.347 1.00 18.07 ? 202 HIS B O 1 ATOM 5069 C CB . HIS B 1 194 ? 176.834 69.447 -66.770 1.00 19.94 ? 202 HIS B CB 1 ATOM 5070 C CG . HIS B 1 194 ? 178.073 69.322 -65.939 1.00 21.87 ? 202 HIS B CG 1 ATOM 5071 N ND1 . HIS B 1 194 ? 178.348 70.165 -64.883 1.00 21.57 ? 202 HIS B ND1 1 ATOM 5072 C CD2 . HIS B 1 194 ? 179.073 68.408 -65.962 1.00 22.11 ? 202 HIS B CD2 1 ATOM 5073 C CE1 . HIS B 1 194 ? 179.461 69.773 -64.288 1.00 21.62 ? 202 HIS B CE1 1 ATOM 5074 N NE2 . HIS B 1 194 ? 179.920 68.709 -64.922 1.00 21.94 ? 202 HIS B NE2 1 ATOM 5075 N N . GLU B 1 195 ? 173.397 68.680 -67.152 1.00 18.50 ? 203 GLU B N 1 ATOM 5076 C CA . GLU B 1 195 ? 172.111 69.231 -67.538 1.00 17.46 ? 203 GLU B CA 1 ATOM 5077 C C . GLU B 1 195 ? 171.059 68.851 -66.495 1.00 17.65 ? 203 GLU B C 1 ATOM 5078 O O . GLU B 1 195 ? 169.987 69.459 -66.445 1.00 17.47 ? 203 GLU B O 1 ATOM 5079 C CB . GLU B 1 195 ? 171.683 68.715 -68.909 1.00 17.78 ? 203 GLU B CB 1 ATOM 5080 C CG . GLU B 1 195 ? 172.223 69.514 -70.089 1.00 20.71 ? 203 GLU B CG 1 ATOM 5081 C CD . GLU B 1 195 ? 173.692 69.266 -70.360 1.00 20.61 ? 203 GLU B CD 1 ATOM 5082 O OE1 . GLU B 1 195 ? 174.051 68.109 -70.652 1.00 21.96 ? 203 GLU B OE1 1 ATOM 5083 O OE2 . GLU B 1 195 ? 174.486 70.229 -70.290 1.00 21.61 ? 203 GLU B OE2 1 ATOM 5084 N N . ILE B 1 196 ? 171.362 67.852 -65.662 1.00 16.12 ? 204 ILE B N 1 ATOM 5085 C CA . ILE B 1 196 ? 170.418 67.416 -64.629 1.00 16.91 ? 204 ILE B CA 1 ATOM 5086 C C . ILE B 1 196 ? 170.020 68.610 -63.756 1.00 17.26 ? 204 ILE B C 1 ATOM 5087 O O . ILE B 1 196 ? 168.847 68.884 -63.553 1.00 16.69 ? 204 ILE B O 1 ATOM 5088 C CB . ILE B 1 196 ? 171.028 66.307 -63.720 1.00 15.79 ? 204 ILE B CB 1 ATOM 5089 C CG1 . ILE B 1 196 ? 171.396 65.078 -64.556 1.00 13.09 ? 204 ILE B CG1 1 ATOM 5090 C CG2 . ILE B 1 196 ? 170.022 65.900 -62.644 1.00 14.13 ? 204 ILE B CG2 1 ATOM 5091 C CD1 . ILE B 1 196 ? 172.197 64.042 -63.790 1.00 11.49 ? 204 ILE B CD1 1 ATOM 5092 N N . GLU B 1 197 ? 171.017 69.321 -63.251 1.00 19.80 ? 205 GLU B N 1 ATOM 5093 C CA . GLU B 1 197 ? 170.809 70.488 -62.398 1.00 21.22 ? 205 GLU B CA 1 ATOM 5094 C C . GLU B 1 197 ? 169.765 70.282 -61.312 1.00 20.97 ? 205 GLU B C 1 ATOM 5095 O O . GLU B 1 197 ? 168.811 71.051 -61.191 1.00 20.52 ? 205 GLU B O 1 ATOM 5096 C CB . GLU B 1 197 ? 170.455 71.719 -63.244 1.00 21.60 ? 205 GLU B CB 1 ATOM 5097 C CG . GLU B 1 197 ? 171.557 72.107 -64.231 1.00 23.57 ? 205 GLU B CG 1 ATOM 5098 C CD . GLU B 1 197 ? 171.460 73.547 -64.697 1.00 25.23 ? 205 GLU B CD 1 ATOM 5099 O OE1 . GLU B 1 197 ? 171.611 74.442 -63.838 1.00 27.96 ? 205 GLU B OE1 1 ATOM 5100 O OE2 . GLU B 1 197 ? 171.234 73.781 -65.908 1.00 23.78 ? 205 GLU B OE2 1 ATOM 5101 N N . PHE B 1 198 ? 169.963 69.236 -60.518 1.00 21.09 ? 206 PHE B N 1 ATOM 5102 C CA . PHE B 1 198 ? 169.065 68.919 -59.416 1.00 21.58 ? 206 PHE B CA 1 ATOM 5103 C C . PHE B 1 198 ? 169.593 69.658 -58.190 1.00 21.54 ? 206 PHE B C 1 ATOM 5104 O O . PHE B 1 198 ? 170.591 69.250 -57.600 1.00 22.69 ? 206 PHE B O 1 ATOM 5105 C CB . PHE B 1 198 ? 169.078 67.414 -59.169 1.00 22.60 ? 206 PHE B CB 1 ATOM 5106 C CG . PHE B 1 198 ? 168.268 66.984 -57.988 1.00 22.73 ? 206 PHE B CG 1 ATOM 5107 C CD1 . PHE B 1 198 ? 166.901 67.243 -57.936 1.00 23.15 ? 206 PHE B CD1 1 ATOM 5108 C CD2 . PHE B 1 198 ? 168.871 66.314 -56.923 1.00 23.03 ? 206 PHE B CD2 1 ATOM 5109 C CE1 . PHE B 1 198 ? 166.136 66.844 -56.841 1.00 22.38 ? 206 PHE B CE1 1 ATOM 5110 C CE2 . PHE B 1 198 ? 168.120 65.908 -55.822 1.00 23.54 ? 206 PHE B CE2 1 ATOM 5111 C CZ . PHE B 1 198 ? 166.745 66.176 -55.782 1.00 23.69 ? 206 PHE B CZ 1 ATOM 5112 N N . ALA B 1 199 ? 168.931 70.742 -57.803 1.00 21.27 ? 207 ALA B N 1 ATOM 5113 C CA . ALA B 1 199 ? 169.398 71.523 -56.664 1.00 22.87 ? 207 ALA B CA 1 ATOM 5114 C C . ALA B 1 199 ? 168.356 71.750 -55.564 1.00 24.05 ? 207 ALA B C 1 ATOM 5115 O O . ALA B 1 199 ? 167.789 72.838 -55.448 1.00 24.69 ? 207 ALA B O 1 ATOM 5116 C CB . ALA B 1 199 ? 169.932 72.863 -57.160 1.00 22.69 ? 207 ALA B CB 1 ATOM 5117 N N . PRO B 1 200 ? 168.118 70.733 -54.718 1.00 24.58 ? 208 PRO B N 1 ATOM 5118 C CA . PRO B 1 200 ? 167.142 70.835 -53.628 1.00 25.38 ? 208 PRO B CA 1 ATOM 5119 C C . PRO B 1 200 ? 167.335 72.071 -52.744 1.00 26.52 ? 208 PRO B C 1 ATOM 5120 O O . PRO B 1 200 ? 166.363 72.694 -52.317 1.00 25.33 ? 208 PRO B O 1 ATOM 5121 C CB . PRO B 1 200 ? 167.362 69.542 -52.840 1.00 23.49 ? 208 PRO B CB 1 ATOM 5122 C CG . PRO B 1 200 ? 167.866 68.598 -53.851 1.00 23.21 ? 208 PRO B CG 1 ATOM 5123 C CD . PRO B 1 200 ? 168.812 69.434 -54.670 1.00 24.27 ? 208 PRO B CD 1 ATOM 5124 N N . GLU B 1 201 ? 168.591 72.413 -52.467 1.00 28.50 ? 209 GLU B N 1 ATOM 5125 C CA . GLU B 1 201 ? 168.900 73.557 -51.620 1.00 31.25 ? 209 GLU B CA 1 ATOM 5126 C C . GLU B 1 201 ? 168.128 74.779 -52.070 1.00 31.67 ? 209 GLU B C 1 ATOM 5127 O O . GLU B 1 201 ? 167.429 75.412 -51.279 1.00 32.96 ? 209 GLU B O 1 ATOM 5128 C CB . GLU B 1 201 ? 170.391 73.891 -51.669 1.00 35.09 ? 209 GLU B CB 1 ATOM 5129 C CG . GLU B 1 201 ? 171.305 72.728 -51.992 1.00 41.20 ? 209 GLU B CG 1 ATOM 5130 C CD . GLU B 1 201 ? 171.341 72.403 -53.474 1.00 43.80 ? 209 GLU B CD 1 ATOM 5131 O OE1 . GLU B 1 201 ? 171.609 73.322 -54.284 1.00 44.03 ? 209 GLU B OE1 1 ATOM 5132 O OE2 . GLU B 1 201 ? 171.106 71.225 -53.822 1.00 46.06 ? 209 GLU B OE2 1 ATOM 5133 N N . ILE B 1 202 ? 168.253 75.105 -53.348 1.00 30.50 ? 210 ILE B N 1 ATOM 5134 C CA . ILE B 1 202 ? 167.577 76.272 -53.881 1.00 29.99 ? 210 ILE B CA 1 ATOM 5135 C C . ILE B 1 202 ? 166.178 75.984 -54.422 1.00 29.90 ? 210 ILE B C 1 ATOM 5136 O O . ILE B 1 202 ? 165.638 76.741 -55.226 1.00 30.79 ? 210 ILE B O 1 ATOM 5137 C CB . ILE B 1 202 ? 168.450 76.934 -54.958 1.00 30.82 ? 210 ILE B CB 1 ATOM 5138 C CG1 . ILE B 1 202 ? 168.851 75.902 -56.010 1.00 31.00 ? 210 ILE B CG1 1 ATOM 5139 C CG2 . ILE B 1 202 ? 169.702 77.515 -54.307 1.00 30.48 ? 210 ILE B CG2 1 ATOM 5140 C CD1 . ILE B 1 202 ? 169.755 76.459 -57.091 1.00 31.25 ? 210 ILE B CD1 1 ATOM 5141 N N . ASN B 1 203 ? 165.593 74.885 -53.962 1.00 30.17 ? 211 ASN B N 1 ATOM 5142 C CA . ASN B 1 203 ? 164.247 74.486 -54.362 1.00 30.25 ? 211 ASN B CA 1 ATOM 5143 C C . ASN B 1 203 ? 164.050 74.255 -55.861 1.00 29.13 ? 211 ASN B C 1 ATOM 5144 O O . ASN B 1 203 ? 162.999 74.566 -56.402 1.00 29.28 ? 211 ASN B O 1 ATOM 5145 C CB . ASN B 1 203 ? 163.237 75.522 -53.871 1.00 34.51 ? 211 ASN B CB 1 ATOM 5146 C CG . ASN B 1 203 ? 161.925 74.892 -53.397 1.00 40.51 ? 211 ASN B CG 1 ATOM 5147 O OD1 . ASN B 1 203 ? 161.169 74.303 -54.180 1.00 41.96 ? 211 ASN B OD1 1 ATOM 5148 N ND2 . ASN B 1 203 ? 161.650 75.020 -52.099 1.00 44.55 ? 211 ASN B ND2 1 ATOM 5149 N N . GLU B 1 204 ? 165.068 73.732 -56.538 1.00 28.52 ? 212 GLU B N 1 ATOM 5150 C CA . GLU B 1 204 ? 164.969 73.424 -57.967 1.00 25.91 ? 212 GLU B CA 1 ATOM 5151 C C . GLU B 1 204 ? 165.130 71.919 -58.049 1.00 25.92 ? 212 GLU B C 1 ATOM 5152 O O . GLU B 1 204 ? 166.243 71.406 -58.163 1.00 25.04 ? 212 GLU B O 1 ATOM 5153 C CB . GLU B 1 204 ? 166.072 74.110 -58.763 1.00 24.42 ? 212 GLU B CB 1 ATOM 5154 C CG . GLU B 1 204 ? 165.848 75.600 -58.970 1.00 26.27 ? 212 GLU B CG 1 ATOM 5155 C CD . GLU B 1 204 ? 164.484 75.917 -59.576 1.00 26.81 ? 212 GLU B CD 1 ATOM 5156 O OE1 . GLU B 1 204 ? 164.099 75.278 -60.574 1.00 28.21 ? 212 GLU B OE1 1 ATOM 5157 O OE2 . GLU B 1 204 ? 163.795 76.817 -59.058 1.00 27.54 ? 212 GLU B OE2 1 ATOM 5158 N N . THR B 1 205 ? 164.002 71.219 -57.985 1.00 25.32 ? 213 THR B N 1 ATOM 5159 C CA . THR B 1 205 ? 164.001 69.769 -57.985 1.00 25.24 ? 213 THR B CA 1 ATOM 5160 C C . THR B 1 205 ? 163.601 69.058 -59.274 1.00 26.25 ? 213 THR B C 1 ATOM 5161 O O . THR B 1 205 ? 163.617 67.833 -59.323 1.00 27.68 ? 213 THR B O 1 ATOM 5162 C CB . THR B 1 205 ? 163.100 69.263 -56.856 1.00 25.58 ? 213 THR B CB 1 ATOM 5163 O OG1 . THR B 1 205 ? 161.781 69.791 -57.039 1.00 25.35 ? 213 THR B OG1 1 ATOM 5164 C CG2 . THR B 1 205 ? 163.635 69.721 -55.501 1.00 23.44 ? 213 THR B CG2 1 ATOM 5165 N N . GLU B 1 206 ? 163.234 69.795 -60.312 1.00 26.40 ? 214 GLU B N 1 ATOM 5166 C CA . GLU B 1 206 ? 162.862 69.139 -61.555 1.00 27.46 ? 214 GLU B CA 1 ATOM 5167 C C . GLU B 1 206 ? 164.089 68.979 -62.452 1.00 25.40 ? 214 GLU B C 1 ATOM 5168 O O . GLU B 1 206 ? 164.647 69.956 -62.947 1.00 26.05 ? 214 GLU B O 1 ATOM 5169 C CB . GLU B 1 206 ? 161.781 69.931 -62.287 1.00 33.12 ? 214 GLU B CB 1 ATOM 5170 C CG . GLU B 1 206 ? 161.334 69.252 -63.581 1.00 43.75 ? 214 GLU B CG 1 ATOM 5171 C CD . GLU B 1 206 ? 160.154 69.942 -64.259 1.00 49.32 ? 214 GLU B CD 1 ATOM 5172 O OE1 . GLU B 1 206 ? 160.291 71.126 -64.666 1.00 51.66 ? 214 GLU B OE1 1 ATOM 5173 O OE2 . GLU B 1 206 ? 159.090 69.288 -64.380 1.00 51.96 ? 214 GLU B OE2 1 ATOM 5174 N N . PRO B 1 207 ? 164.517 67.734 -62.687 1.00 23.24 ? 215 PRO B N 1 ATOM 5175 C CA . PRO B 1 207 ? 165.688 67.473 -63.527 1.00 21.44 ? 215 PRO B CA 1 ATOM 5176 C C . PRO B 1 207 ? 165.586 68.040 -64.945 1.00 21.13 ? 215 PRO B C 1 ATOM 5177 O O . PRO B 1 207 ? 164.513 68.035 -65.545 1.00 21.38 ? 215 PRO B O 1 ATOM 5178 C CB . PRO B 1 207 ? 165.778 65.948 -63.531 1.00 20.38 ? 215 PRO B CB 1 ATOM 5179 C CG . PRO B 1 207 ? 165.137 65.558 -62.236 1.00 20.84 ? 215 PRO B CG 1 ATOM 5180 C CD . PRO B 1 207 ? 163.953 66.478 -62.169 1.00 20.77 ? 215 PRO B CD 1 ATOM 5181 N N . PHE B 1 208 ? 166.715 68.524 -65.461 1.00 19.62 ? 216 PHE B N 1 ATOM 5182 C CA . PHE B 1 208 ? 166.819 69.063 -66.814 1.00 18.10 ? 216 PHE B CA 1 ATOM 5183 C C . PHE B 1 208 ? 165.990 70.308 -67.099 1.00 17.95 ? 216 PHE B C 1 ATOM 5184 O O . PHE B 1 208 ? 165.746 70.623 -68.268 1.00 17.84 ? 216 PHE B O 1 ATOM 5185 C CB . PHE B 1 208 ? 166.421 67.988 -67.821 1.00 16.93 ? 216 PHE B CB 1 ATOM 5186 C CG . PHE B 1 208 ? 167.180 66.710 -67.672 1.00 18.12 ? 216 PHE B CG 1 ATOM 5187 C CD1 . PHE B 1 208 ? 168.531 66.644 -67.990 1.00 17.09 ? 216 PHE B CD1 1 ATOM 5188 C CD2 . PHE B 1 208 ? 166.538 65.562 -67.214 1.00 18.52 ? 216 PHE B CD2 1 ATOM 5189 C CE1 . PHE B 1 208 ? 169.237 65.450 -67.854 1.00 18.66 ? 216 PHE B CE1 1 ATOM 5190 C CE2 . PHE B 1 208 ? 167.228 64.359 -67.073 1.00 19.53 ? 216 PHE B CE2 1 ATOM 5191 C CZ . PHE B 1 208 ? 168.583 64.300 -67.393 1.00 19.25 ? 216 PHE B CZ 1 ATOM 5192 N N . LYS B 1 209 ? 165.568 71.028 -66.064 1.00 17.48 ? 217 LYS B N 1 ATOM 5193 C CA . LYS B 1 209 ? 164.733 72.204 -66.287 1.00 16.74 ? 217 LYS B CA 1 ATOM 5194 C C . LYS B 1 209 ? 165.316 73.259 -67.236 1.00 16.21 ? 217 LYS B C 1 ATOM 5195 O O . LYS B 1 209 ? 164.764 73.497 -68.310 1.00 16.21 ? 217 LYS B O 1 ATOM 5196 C CB . LYS B 1 209 ? 164.365 72.848 -64.955 1.00 16.45 ? 217 LYS B CB 1 ATOM 5197 C CG . LYS B 1 209 ? 163.375 73.996 -65.070 1.00 16.20 ? 217 LYS B CG 1 ATOM 5198 C CD . LYS B 1 209 ? 163.083 74.519 -63.678 1.00 18.89 ? 217 LYS B CD 1 ATOM 5199 C CE . LYS B 1 209 ? 162.134 75.700 -63.673 1.00 21.29 ? 217 LYS B CE 1 ATOM 5200 N NZ . LYS B 1 209 ? 161.967 76.233 -62.278 1.00 19.46 ? 217 LYS B NZ 1 ATOM 5201 N N . PRO B 1 210 ? 166.443 73.893 -66.870 1.00 15.92 ? 218 PRO B N 1 ATOM 5202 C CA . PRO B 1 210 ? 166.989 74.906 -67.783 1.00 15.58 ? 218 PRO B CA 1 ATOM 5203 C C . PRO B 1 210 ? 167.162 74.347 -69.191 1.00 17.50 ? 218 PRO B C 1 ATOM 5204 O O . PRO B 1 210 ? 166.682 74.923 -70.166 1.00 17.50 ? 218 PRO B O 1 ATOM 5205 C CB . PRO B 1 210 ? 168.332 75.272 -67.144 1.00 16.32 ? 218 PRO B CB 1 ATOM 5206 C CG . PRO B 1 210 ? 168.128 74.939 -65.683 1.00 16.17 ? 218 PRO B CG 1 ATOM 5207 C CD . PRO B 1 210 ? 167.364 73.642 -65.750 1.00 14.94 ? 218 PRO B CD 1 ATOM 5208 N N . PHE B 1 211 ? 167.847 73.211 -69.288 1.00 18.99 ? 219 PHE B N 1 ATOM 5209 C CA . PHE B 1 211 ? 168.091 72.561 -70.571 1.00 19.17 ? 219 PHE B CA 1 ATOM 5210 C C . PHE B 1 211 ? 166.837 72.343 -71.412 1.00 19.70 ? 219 PHE B C 1 ATOM 5211 O O . PHE B 1 211 ? 166.777 72.786 -72.561 1.00 19.85 ? 219 PHE B O 1 ATOM 5212 C CB . PHE B 1 211 ? 168.788 71.211 -70.352 1.00 18.95 ? 219 PHE B CB 1 ATOM 5213 C CG . PHE B 1 211 ? 168.951 70.396 -71.612 1.00 18.45 ? 219 PHE B CG 1 ATOM 5214 C CD1 . PHE B 1 211 ? 169.807 70.815 -72.623 1.00 18.88 ? 219 PHE B CD1 1 ATOM 5215 C CD2 . PHE B 1 211 ? 168.248 69.205 -71.780 1.00 18.96 ? 219 PHE B CD2 1 ATOM 5216 C CE1 . PHE B 1 211 ? 169.961 70.060 -73.781 1.00 18.67 ? 219 PHE B CE1 1 ATOM 5217 C CE2 . PHE B 1 211 ? 168.394 68.445 -72.931 1.00 19.15 ? 219 PHE B CE2 1 ATOM 5218 C CZ . PHE B 1 211 ? 169.253 68.873 -73.934 1.00 19.40 ? 219 PHE B CZ 1 ATOM 5219 N N . SER B 1 212 ? 165.842 71.662 -70.841 1.00 19.57 ? 220 SER B N 1 ATOM 5220 C CA . SER B 1 212 ? 164.616 71.350 -71.574 1.00 20.61 ? 220 SER B CA 1 ATOM 5221 C C . SER B 1 212 ? 163.873 72.571 -72.091 1.00 20.47 ? 220 SER B C 1 ATOM 5222 O O . SER B 1 212 ? 163.222 72.502 -73.133 1.00 19.61 ? 220 SER B O 1 ATOM 5223 C CB . SER B 1 212 ? 163.680 70.496 -70.719 1.00 20.51 ? 220 SER B CB 1 ATOM 5224 O OG . SER B 1 212 ? 163.317 71.192 -69.544 1.00 25.62 ? 220 SER B OG 1 ATOM 5225 N N . TYR B 1 213 ? 163.956 73.686 -71.371 1.00 20.29 ? 221 TYR B N 1 ATOM 5226 C CA . TYR B 1 213 ? 163.285 74.904 -71.817 1.00 20.67 ? 221 TYR B CA 1 ATOM 5227 C C . TYR B 1 213 ? 164.007 75.536 -73.004 1.00 20.96 ? 221 TYR B C 1 ATOM 5228 O O . TYR B 1 213 ? 163.381 75.961 -73.977 1.00 20.96 ? 221 TYR B O 1 ATOM 5229 C CB . TYR B 1 213 ? 163.214 75.917 -70.681 1.00 20.33 ? 221 TYR B CB 1 ATOM 5230 C CG . TYR B 1 213 ? 161.928 75.875 -69.903 1.00 22.23 ? 221 TYR B CG 1 ATOM 5231 C CD1 . TYR B 1 213 ? 160.771 76.466 -70.405 1.00 23.15 ? 221 TYR B CD1 1 ATOM 5232 C CD2 . TYR B 1 213 ? 161.872 75.269 -68.649 1.00 23.21 ? 221 TYR B CD2 1 ATOM 5233 C CE1 . TYR B 1 213 ? 159.587 76.461 -69.674 1.00 25.30 ? 221 TYR B CE1 1 ATOM 5234 C CE2 . TYR B 1 213 ? 160.694 75.257 -67.907 1.00 25.47 ? 221 TYR B CE2 1 ATOM 5235 C CZ . TYR B 1 213 ? 159.557 75.856 -68.424 1.00 26.60 ? 221 TYR B CZ 1 ATOM 5236 O OH . TYR B 1 213 ? 158.396 75.862 -67.681 1.00 28.26 ? 221 TYR B OH 1 ATOM 5237 N N . ARG B 1 214 ? 165.330 75.594 -72.915 1.00 19.86 ? 222 ARG B N 1 ATOM 5238 C CA . ARG B 1 214 ? 166.135 76.192 -73.961 1.00 18.78 ? 222 ARG B CA 1 ATOM 5239 C C . ARG B 1 214 ? 166.313 75.315 -75.198 1.00 19.69 ? 222 ARG B C 1 ATOM 5240 O O . ARG B 1 214 ? 166.350 75.839 -76.311 1.00 20.20 ? 222 ARG B O 1 ATOM 5241 C CB . ARG B 1 214 ? 167.503 76.589 -73.393 1.00 16.30 ? 222 ARG B CB 1 ATOM 5242 C CG . ARG B 1 214 ? 167.413 77.704 -72.371 1.00 16.69 ? 222 ARG B CG 1 ATOM 5243 C CD . ARG B 1 214 ? 168.702 77.893 -71.594 1.00 18.12 ? 222 ARG B CD 1 ATOM 5244 N NE . ARG B 1 214 ? 168.566 78.986 -70.634 1.00 21.64 ? 222 ARG B NE 1 ATOM 5245 C CZ . ARG B 1 214 ? 168.918 80.248 -70.871 1.00 23.11 ? 222 ARG B CZ 1 ATOM 5246 N NH1 . ARG B 1 214 ? 169.444 80.583 -72.038 1.00 21.80 ? 222 ARG B NH1 1 ATOM 5247 N NH2 . ARG B 1 214 ? 168.717 81.184 -69.950 1.00 24.09 ? 222 ARG B NH2 1 ATOM 5248 N N . TYR B 1 215 ? 166.408 73.996 -75.027 1.00 19.29 ? 223 TYR B N 1 ATOM 5249 C CA . TYR B 1 215 ? 166.612 73.118 -76.183 1.00 19.45 ? 223 TYR B CA 1 ATOM 5250 C C . TYR B 1 215 ? 165.530 72.071 -76.448 1.00 19.78 ? 223 TYR B C 1 ATOM 5251 O O . TYR B 1 215 ? 165.368 71.124 -75.679 1.00 20.45 ? 223 TYR B O 1 ATOM 5252 C CB . TYR B 1 215 ? 167.981 72.429 -76.072 1.00 18.13 ? 223 TYR B CB 1 ATOM 5253 C CG . TYR B 1 215 ? 169.128 73.417 -76.020 1.00 18.16 ? 223 TYR B CG 1 ATOM 5254 C CD1 . TYR B 1 215 ? 169.528 73.984 -74.814 1.00 15.66 ? 223 TYR B CD1 1 ATOM 5255 C CD2 . TYR B 1 215 ? 169.736 73.872 -77.195 1.00 17.67 ? 223 TYR B CD2 1 ATOM 5256 C CE1 . TYR B 1 215 ? 170.493 74.987 -74.779 1.00 13.91 ? 223 TYR B CE1 1 ATOM 5257 C CE2 . TYR B 1 215 ? 170.696 74.872 -77.171 1.00 13.82 ? 223 TYR B CE2 1 ATOM 5258 C CZ . TYR B 1 215 ? 171.066 75.427 -75.965 1.00 13.11 ? 223 TYR B CZ 1 ATOM 5259 O OH . TYR B 1 215 ? 171.977 76.459 -75.963 1.00 13.37 ? 223 TYR B OH 1 ATOM 5260 N N . HIS B 1 216 ? 164.795 72.241 -77.544 1.00 19.20 ? 224 HIS B N 1 ATOM 5261 C CA . HIS B 1 216 ? 163.747 71.295 -77.903 1.00 19.49 ? 224 HIS B CA 1 ATOM 5262 C C . HIS B 1 216 ? 164.264 70.320 -78.949 1.00 19.28 ? 224 HIS B C 1 ATOM 5263 O O . HIS B 1 216 ? 165.169 70.638 -79.707 1.00 20.98 ? 224 HIS B O 1 ATOM 5264 C CB . HIS B 1 216 ? 162.509 72.029 -78.435 1.00 20.03 ? 224 HIS B CB 1 ATOM 5265 C CG . HIS B 1 216 ? 161.709 72.712 -77.366 1.00 22.22 ? 224 HIS B CG 1 ATOM 5266 N ND1 . HIS B 1 216 ? 160.374 73.023 -77.513 1.00 22.70 ? 224 HIS B ND1 1 ATOM 5267 C CD2 . HIS B 1 216 ? 162.057 73.127 -76.124 1.00 21.91 ? 224 HIS B CD2 1 ATOM 5268 C CE1 . HIS B 1 216 ? 159.933 73.597 -76.406 1.00 22.20 ? 224 HIS B CE1 1 ATOM 5269 N NE2 . HIS B 1 216 ? 160.934 73.671 -75.548 1.00 21.98 ? 224 HIS B NE2 1 ATOM 5270 N N . VAL B 1 217 ? 163.689 69.124 -78.970 1.00 20.11 ? 225 VAL B N 1 ATOM 5271 C CA . VAL B 1 217 ? 164.068 68.076 -79.915 1.00 20.43 ? 225 VAL B CA 1 ATOM 5272 C C . VAL B 1 217 ? 162.786 67.455 -80.483 1.00 20.14 ? 225 VAL B C 1 ATOM 5273 O O . VAL B 1 217 ? 161.725 67.532 -79.853 1.00 20.40 ? 225 VAL B O 1 ATOM 5274 C CB . VAL B 1 217 ? 164.904 66.974 -79.209 1.00 20.23 ? 225 VAL B CB 1 ATOM 5275 C CG1 . VAL B 1 217 ? 166.130 67.595 -78.542 1.00 17.84 ? 225 VAL B CG1 1 ATOM 5276 C CG2 . VAL B 1 217 ? 164.052 66.260 -78.176 1.00 18.48 ? 225 VAL B CG2 1 ATOM 5277 N N . PRO B 1 218 ? 162.862 66.833 -81.677 1.00 19.54 ? 226 PRO B N 1 ATOM 5278 C CA . PRO B 1 218 ? 161.702 66.204 -82.322 1.00 20.28 ? 226 PRO B CA 1 ATOM 5279 C C . PRO B 1 218 ? 161.454 64.790 -81.798 1.00 21.47 ? 226 PRO B C 1 ATOM 5280 O O . PRO B 1 218 ? 161.293 63.848 -82.577 1.00 22.30 ? 226 PRO B O 1 ATOM 5281 C CB . PRO B 1 218 ? 162.106 66.195 -83.782 1.00 18.05 ? 226 PRO B CB 1 ATOM 5282 C CG . PRO B 1 218 ? 163.552 65.821 -83.679 1.00 17.91 ? 226 PRO B CG 1 ATOM 5283 C CD . PRO B 1 218 ? 164.046 66.728 -82.551 1.00 20.21 ? 226 PRO B CD 1 ATOM 5284 N N . TYR B 1 219 ? 161.410 64.643 -80.478 1.00 22.04 ? 227 TYR B N 1 ATOM 5285 C CA . TYR B 1 219 ? 161.218 63.330 -79.875 1.00 22.65 ? 227 TYR B CA 1 ATOM 5286 C C . TYR B 1 219 ? 159.907 62.656 -80.241 1.00 23.25 ? 227 TYR B C 1 ATOM 5287 O O . TYR B 1 219 ? 159.827 61.428 -80.296 1.00 22.58 ? 227 TYR B O 1 ATOM 5288 C CB . TYR B 1 219 ? 161.363 63.419 -78.351 1.00 21.34 ? 227 TYR B CB 1 ATOM 5289 C CG . TYR B 1 219 ? 160.275 64.183 -77.637 1.00 19.29 ? 227 TYR B CG 1 ATOM 5290 C CD1 . TYR B 1 219 ? 159.120 63.538 -77.199 1.00 18.73 ? 227 TYR B CD1 1 ATOM 5291 C CD2 . TYR B 1 219 ? 160.424 65.536 -77.347 1.00 18.84 ? 227 TYR B CD2 1 ATOM 5292 C CE1 . TYR B 1 219 ? 158.142 64.219 -76.480 1.00 16.77 ? 227 TYR B CE1 1 ATOM 5293 C CE2 . TYR B 1 219 ? 159.451 66.227 -76.631 1.00 18.76 ? 227 TYR B CE2 1 ATOM 5294 C CZ . TYR B 1 219 ? 158.315 65.561 -76.196 1.00 18.34 ? 227 TYR B CZ 1 ATOM 5295 O OH . TYR B 1 219 ? 157.367 66.228 -75.454 1.00 16.93 ? 227 TYR B OH 1 ATOM 5296 N N . GLU B 1 220 ? 158.878 63.449 -80.505 1.00 24.08 ? 228 GLU B N 1 ATOM 5297 C CA . GLU B 1 220 ? 157.598 62.869 -80.858 1.00 25.18 ? 228 GLU B CA 1 ATOM 5298 C C . GLU B 1 220 ? 157.633 62.199 -82.219 1.00 23.60 ? 228 GLU B C 1 ATOM 5299 O O . GLU B 1 220 ? 156.858 61.282 -82.476 1.00 23.24 ? 228 GLU B O 1 ATOM 5300 C CB . GLU B 1 220 ? 156.506 63.936 -80.786 1.00 29.62 ? 228 GLU B CB 1 ATOM 5301 C CG . GLU B 1 220 ? 156.079 64.187 -79.348 1.00 38.13 ? 228 GLU B CG 1 ATOM 5302 C CD . GLU B 1 220 ? 155.290 65.463 -79.151 1.00 43.49 ? 228 GLU B CD 1 ATOM 5303 O OE1 . GLU B 1 220 ? 155.860 66.556 -79.384 1.00 46.40 ? 228 GLU B OE1 1 ATOM 5304 O OE2 . GLU B 1 220 ? 154.105 65.367 -78.756 1.00 46.71 ? 228 GLU B OE2 1 ATOM 5305 N N . ALA B 1 221 ? 158.552 62.633 -83.074 1.00 22.64 ? 229 ALA B N 1 ATOM 5306 C CA . ALA B 1 221 ? 158.677 62.056 -84.407 1.00 22.81 ? 229 ALA B CA 1 ATOM 5307 C C . ALA B 1 221 ? 158.991 60.560 -84.369 1.00 24.08 ? 229 ALA B C 1 ATOM 5308 O O . ALA B 1 221 ? 158.695 59.842 -85.325 1.00 25.65 ? 229 ALA B O 1 ATOM 5309 C CB . ALA B 1 221 ? 159.752 62.796 -85.206 1.00 21.13 ? 229 ALA B CB 1 ATOM 5310 N N . SER B 1 222 ? 159.590 60.085 -83.280 1.00 23.46 ? 230 SER B N 1 ATOM 5311 C CA . SER B 1 222 ? 159.916 58.665 -83.175 1.00 23.49 ? 230 SER B CA 1 ATOM 5312 C C . SER B 1 222 ? 159.078 57.917 -82.132 1.00 24.59 ? 230 SER B C 1 ATOM 5313 O O . SER B 1 222 ? 159.498 56.877 -81.619 1.00 25.05 ? 230 SER B O 1 ATOM 5314 C CB . SER B 1 222 ? 161.406 58.483 -82.867 1.00 23.82 ? 230 SER B CB 1 ATOM 5315 O OG . SER B 1 222 ? 161.767 59.136 -81.661 1.00 22.28 ? 230 SER B OG 1 ATOM 5316 N N . GLN B 1 223 ? 157.895 58.437 -81.818 1.00 24.33 ? 231 GLN B N 1 ATOM 5317 C CA . GLN B 1 223 ? 157.026 57.780 -80.844 1.00 26.53 ? 231 GLN B CA 1 ATOM 5318 C C . GLN B 1 223 ? 157.562 57.798 -79.418 1.00 25.50 ? 231 GLN B C 1 ATOM 5319 O O . GLN B 1 223 ? 157.126 57.003 -78.583 1.00 26.07 ? 231 GLN B O 1 ATOM 5320 C CB . GLN B 1 223 ? 156.771 56.321 -81.241 1.00 31.22 ? 231 GLN B CB 1 ATOM 5321 C CG . GLN B 1 223 ? 155.568 56.086 -82.134 1.00 37.20 ? 231 GLN B CG 1 ATOM 5322 C CD . GLN B 1 223 ? 155.685 56.786 -83.462 1.00 42.36 ? 231 GLN B CD 1 ATOM 5323 O OE1 . GLN B 1 223 ? 156.599 56.516 -84.249 1.00 45.43 ? 231 GLN B OE1 1 ATOM 5324 N NE2 . GLN B 1 223 ? 154.758 57.701 -83.724 1.00 45.72 ? 231 GLN B NE2 1 ATOM 5325 N N . SER B 1 224 ? 158.511 58.681 -79.136 1.00 23.16 ? 232 SER B N 1 ATOM 5326 C CA . SER B 1 224 ? 159.051 58.780 -77.787 1.00 22.05 ? 232 SER B CA 1 ATOM 5327 C C . SER B 1 224 ? 158.102 59.605 -76.920 1.00 22.12 ? 232 SER B C 1 ATOM 5328 O O . SER B 1 224 ? 157.284 60.372 -77.432 1.00 23.44 ? 232 SER B O 1 ATOM 5329 C CB . SER B 1 224 ? 160.430 59.444 -77.811 1.00 21.50 ? 232 SER B CB 1 ATOM 5330 O OG . SER B 1 224 ? 160.819 59.871 -76.518 1.00 19.52 ? 232 SER B OG 1 ATOM 5331 N N . THR B 1 225 ? 158.199 59.451 -75.607 1.00 20.46 ? 233 THR B N 1 ATOM 5332 C CA . THR B 1 225 ? 157.338 60.212 -74.719 1.00 20.14 ? 233 THR B CA 1 ATOM 5333 C C . THR B 1 225 ? 158.158 61.188 -73.886 1.00 21.17 ? 233 THR B C 1 ATOM 5334 O O . THR B 1 225 ? 157.662 61.752 -72.912 1.00 21.72 ? 233 THR B O 1 ATOM 5335 C CB . THR B 1 225 ? 156.544 59.284 -73.778 1.00 19.64 ? 233 THR B CB 1 ATOM 5336 O OG1 . THR B 1 225 ? 157.448 58.476 -73.023 1.00 22.58 ? 233 THR B OG1 1 ATOM 5337 C CG2 . THR B 1 225 ? 155.632 58.368 -74.571 1.00 18.87 ? 233 THR B CG2 1 ATOM 5338 N N . SER B 1 226 ? 159.410 61.401 -74.284 1.00 21.83 ? 234 SER B N 1 ATOM 5339 C CA . SER B 1 226 ? 160.295 62.306 -73.562 1.00 22.59 ? 234 SER B CA 1 ATOM 5340 C C . SER B 1 226 ? 161.397 62.896 -74.443 1.00 22.32 ? 234 SER B C 1 ATOM 5341 O O . SER B 1 226 ? 161.892 62.243 -75.362 1.00 23.84 ? 234 SER B O 1 ATOM 5342 C CB . SER B 1 226 ? 160.933 61.566 -72.383 1.00 24.25 ? 234 SER B CB 1 ATOM 5343 O OG . SER B 1 226 ? 161.911 62.373 -71.753 1.00 26.98 ? 234 SER B OG 1 ATOM 5344 N N . PRO B 1 227 ? 161.802 64.145 -74.166 1.00 20.73 ? 235 PRO B N 1 ATOM 5345 C CA . PRO B 1 227 ? 162.855 64.805 -74.948 1.00 20.04 ? 235 PRO B CA 1 ATOM 5346 C C . PRO B 1 227 ? 164.288 64.343 -74.670 1.00 20.05 ? 235 PRO B C 1 ATOM 5347 O O . PRO B 1 227 ? 165.224 64.833 -75.305 1.00 22.45 ? 235 PRO B O 1 ATOM 5348 C CB . PRO B 1 227 ? 162.664 66.281 -74.597 1.00 18.69 ? 235 PRO B CB 1 ATOM 5349 C CG . PRO B 1 227 ? 162.181 66.221 -73.190 1.00 17.78 ? 235 PRO B CG 1 ATOM 5350 C CD . PRO B 1 227 ? 161.166 65.100 -73.240 1.00 18.21 ? 235 PRO B CD 1 ATOM 5351 N N . PHE B 1 228 ? 164.471 63.405 -73.742 1.00 19.07 ? 236 PHE B N 1 ATOM 5352 C CA . PHE B 1 228 ? 165.821 62.953 -73.397 1.00 17.26 ? 236 PHE B CA 1 ATOM 5353 C C . PHE B 1 228 ? 166.279 61.724 -74.143 1.00 16.79 ? 236 PHE B C 1 ATOM 5354 O O . PHE B 1 228 ? 167.412 61.281 -73.981 1.00 17.65 ? 236 PHE B O 1 ATOM 5355 C CB . PHE B 1 228 ? 165.919 62.748 -71.887 1.00 15.81 ? 236 PHE B CB 1 ATOM 5356 C CG . PHE B 1 228 ? 165.313 63.870 -71.115 1.00 16.68 ? 236 PHE B CG 1 ATOM 5357 C CD1 . PHE B 1 228 ? 164.191 63.660 -70.319 1.00 16.98 ? 236 PHE B CD1 1 ATOM 5358 C CD2 . PHE B 1 228 ? 165.789 65.171 -71.279 1.00 17.20 ? 236 PHE B CD2 1 ATOM 5359 C CE1 . PHE B 1 228 ? 163.543 64.728 -69.711 1.00 15.91 ? 236 PHE B CE1 1 ATOM 5360 C CE2 . PHE B 1 228 ? 165.143 66.250 -70.674 1.00 17.75 ? 236 PHE B CE2 1 ATOM 5361 C CZ . PHE B 1 228 ? 164.017 66.026 -69.889 1.00 17.18 ? 236 PHE B CZ 1 ATOM 5362 N N . TRP B 1 229 ? 165.384 61.165 -74.947 1.00 17.45 ? 237 TRP B N 1 ATOM 5363 C CA . TRP B 1 229 ? 165.702 60.009 -75.776 1.00 17.34 ? 237 TRP B CA 1 ATOM 5364 C C . TRP B 1 229 ? 164.792 60.055 -76.986 1.00 17.09 ? 237 TRP B C 1 ATOM 5365 O O . TRP B 1 229 ? 163.585 60.285 -76.869 1.00 16.65 ? 237 TRP B O 1 ATOM 5366 C CB . TRP B 1 229 ? 165.562 58.687 -75.003 1.00 16.78 ? 237 TRP B CB 1 ATOM 5367 C CG . TRP B 1 229 ? 164.201 58.337 -74.509 1.00 15.62 ? 237 TRP B CG 1 ATOM 5368 C CD1 . TRP B 1 229 ? 163.198 57.746 -75.219 1.00 15.60 ? 237 TRP B CD1 1 ATOM 5369 C CD2 . TRP B 1 229 ? 163.702 58.518 -73.183 1.00 15.98 ? 237 TRP B CD2 1 ATOM 5370 N NE1 . TRP B 1 229 ? 162.102 57.543 -74.417 1.00 15.34 ? 237 TRP B NE1 1 ATOM 5371 C CE2 . TRP B 1 229 ? 162.383 58.015 -73.160 1.00 16.23 ? 237 TRP B CE2 1 ATOM 5372 C CE3 . TRP B 1 229 ? 164.237 59.068 -72.010 1.00 17.40 ? 237 TRP B CE3 1 ATOM 5373 C CZ2 . TRP B 1 229 ? 161.593 58.031 -72.009 1.00 16.26 ? 237 TRP B CZ2 1 ATOM 5374 C CZ3 . TRP B 1 229 ? 163.449 59.084 -70.857 1.00 17.85 ? 237 TRP B CZ3 1 ATOM 5375 C CH2 . TRP B 1 229 ? 162.139 58.572 -70.870 1.00 17.58 ? 237 TRP B CH2 1 ATOM 5376 N N . TYR B 1 230 ? 165.398 59.878 -78.153 1.00 16.96 ? 238 TYR B N 1 ATOM 5377 C CA . TYR B 1 230 ? 164.680 59.931 -79.415 1.00 16.22 ? 238 TYR B CA 1 ATOM 5378 C C . TYR B 1 230 ? 165.658 59.554 -80.513 1.00 17.42 ? 238 TYR B C 1 ATOM 5379 O O . TYR B 1 230 ? 166.862 59.428 -80.276 1.00 17.34 ? 238 TYR B O 1 ATOM 5380 C CB . TYR B 1 230 ? 164.177 61.358 -79.666 1.00 14.72 ? 238 TYR B CB 1 ATOM 5381 C CG . TYR B 1 230 ? 165.297 62.382 -79.757 1.00 13.91 ? 238 TYR B CG 1 ATOM 5382 C CD1 . TYR B 1 230 ? 165.965 62.828 -78.614 1.00 16.04 ? 238 TYR B CD1 1 ATOM 5383 C CD2 . TYR B 1 230 ? 165.727 62.861 -80.992 1.00 13.94 ? 238 TYR B CD2 1 ATOM 5384 C CE1 . TYR B 1 230 ? 167.043 63.730 -78.704 1.00 15.81 ? 238 TYR B CE1 1 ATOM 5385 C CE2 . TYR B 1 230 ? 166.798 63.754 -81.095 1.00 14.13 ? 238 TYR B CE2 1 ATOM 5386 C CZ . TYR B 1 230 ? 167.454 64.183 -79.950 1.00 15.44 ? 238 TYR B CZ 1 ATOM 5387 O OH . TYR B 1 230 ? 168.535 65.043 -80.060 1.00 15.50 ? 238 TYR B OH 1 ATOM 5388 N N . SER B 1 231 ? 165.135 59.376 -81.719 1.00 18.82 ? 239 SER B N 1 ATOM 5389 C CA . SER B 1 231 ? 165.975 59.054 -82.860 1.00 20.76 ? 239 SER B CA 1 ATOM 5390 C C . SER B 1 231 ? 165.550 59.904 -84.040 1.00 21.37 ? 239 SER B C 1 ATOM 5391 O O . SER B 1 231 ? 164.435 60.436 -84.075 1.00 21.61 ? 239 SER B O 1 ATOM 5392 C CB . SER B 1 231 ? 165.828 57.587 -83.246 1.00 20.22 ? 239 SER B CB 1 ATOM 5393 O OG . SER B 1 231 ? 164.507 57.342 -83.684 1.00 24.36 ? 239 SER B OG 1 ATOM 5394 N N . ILE B 1 232 ? 166.454 60.041 -84.999 1.00 20.69 ? 240 ILE B N 1 ATOM 5395 C CA . ILE B 1 232 ? 166.170 60.779 -86.213 1.00 19.86 ? 240 ILE B CA 1 ATOM 5396 C C . ILE B 1 232 ? 166.966 60.109 -87.309 1.00 19.51 ? 240 ILE B C 1 ATOM 5397 O O . ILE B 1 232 ? 167.998 59.484 -87.049 1.00 20.21 ? 240 ILE B O 1 ATOM 5398 C CB . ILE B 1 232 ? 166.622 62.246 -86.135 1.00 18.73 ? 240 ILE B CB 1 ATOM 5399 C CG1 . ILE B 1 232 ? 168.111 62.305 -85.821 1.00 18.49 ? 240 ILE B CG1 1 ATOM 5400 C CG2 . ILE B 1 232 ? 165.795 62.999 -85.118 1.00 19.31 ? 240 ILE B CG2 1 ATOM 5401 C CD1 . ILE B 1 232 ? 168.781 63.526 -86.383 1.00 19.69 ? 240 ILE B CD1 1 ATOM 5402 N N . LYS B 1 233 ? 166.473 60.220 -88.531 1.00 19.57 ? 241 LYS B N 1 ATOM 5403 C CA . LYS B 1 233 ? 167.163 59.656 -89.675 1.00 20.98 ? 241 LYS B CA 1 ATOM 5404 C C . LYS B 1 233 ? 167.686 60.858 -90.463 1.00 20.78 ? 241 LYS B C 1 ATOM 5405 O O . LYS B 1 233 ? 166.965 61.846 -90.638 1.00 20.38 ? 241 LYS B O 1 ATOM 5406 C CB . LYS B 1 233 ? 166.194 58.864 -90.555 1.00 22.16 ? 241 LYS B CB 1 ATOM 5407 C CG . LYS B 1 233 ? 165.572 57.639 -89.922 1.00 24.63 ? 241 LYS B CG 1 ATOM 5408 C CD . LYS B 1 233 ? 164.663 56.933 -90.928 1.00 26.71 ? 241 LYS B CD 1 ATOM 5409 C CE . LYS B 1 233 ? 164.040 55.680 -90.329 1.00 31.60 ? 241 LYS B CE 1 ATOM 5410 N NZ . LYS B 1 233 ? 163.321 54.845 -91.346 1.00 34.61 ? 241 LYS B NZ 1 ATOM 5411 N N . ARG B 1 234 ? 168.929 60.791 -90.925 1.00 19.23 ? 242 ARG B N 1 ATOM 5412 C CA . ARG B 1 234 ? 169.489 61.889 -91.705 1.00 20.23 ? 242 ARG B CA 1 ATOM 5413 C C . ARG B 1 234 ? 170.468 61.315 -92.712 1.00 20.37 ? 242 ARG B C 1 ATOM 5414 O O . ARG B 1 234 ? 171.446 60.663 -92.331 1.00 20.61 ? 242 ARG B O 1 ATOM 5415 C CB . ARG B 1 234 ? 170.176 62.911 -90.791 1.00 19.97 ? 242 ARG B CB 1 ATOM 5416 C CG . ARG B 1 234 ? 170.973 63.986 -91.533 1.00 21.14 ? 242 ARG B CG 1 ATOM 5417 C CD . ARG B 1 234 ? 171.304 65.173 -90.625 1.00 23.12 ? 242 ARG B CD 1 ATOM 5418 N NE . ARG B 1 234 ? 170.134 66.026 -90.435 1.00 25.14 ? 242 ARG B NE 1 ATOM 5419 C CZ . ARG B 1 234 ? 170.015 67.262 -90.912 1.00 24.17 ? 242 ARG B CZ 1 ATOM 5420 N NH1 . ARG B 1 234 ? 171.004 67.811 -91.606 1.00 22.17 ? 242 ARG B NH1 1 ATOM 5421 N NH2 . ARG B 1 234 ? 168.889 67.936 -90.716 1.00 23.83 ? 242 ARG B NH2 1 ATOM 5422 N N . ALA B 1 235 ? 170.202 61.563 -93.995 1.00 19.28 ? 243 ALA B N 1 ATOM 5423 C CA . ALA B 1 235 ? 171.035 61.038 -95.067 1.00 19.27 ? 243 ALA B CA 1 ATOM 5424 C C . ALA B 1 235 ? 171.037 59.516 -94.942 1.00 19.55 ? 243 ALA B C 1 ATOM 5425 O O . ALA B 1 235 ? 169.974 58.901 -94.931 1.00 20.26 ? 243 ALA B O 1 ATOM 5426 C CB . ALA B 1 235 ? 172.456 61.590 -94.970 1.00 19.71 ? 243 ALA B CB 1 ATOM 5427 N N . SER B 1 236 ? 172.213 58.905 -94.836 1.00 19.82 ? 244 SER B N 1 ATOM 5428 C CA . SER B 1 236 ? 172.293 57.448 -94.732 1.00 21.14 ? 244 SER B CA 1 ATOM 5429 C C . SER B 1 236 ? 172.472 56.945 -93.304 1.00 21.03 ? 244 SER B C 1 ATOM 5430 O O . SER B 1 236 ? 172.822 55.781 -93.089 1.00 21.69 ? 244 SER B O 1 ATOM 5431 C CB . SER B 1 236 ? 173.436 56.924 -95.603 1.00 20.45 ? 244 SER B CB 1 ATOM 5432 O OG . SER B 1 236 ? 174.660 57.557 -95.264 1.00 23.91 ? 244 SER B OG 1 ATOM 5433 N N . ALA B 1 237 ? 172.225 57.819 -92.332 1.00 19.89 ? 245 ALA B N 1 ATOM 5434 C CA . ALA B 1 237 ? 172.377 57.454 -90.930 1.00 17.86 ? 245 ALA B CA 1 ATOM 5435 C C . ALA B 1 237 ? 171.074 57.465 -90.156 1.00 17.23 ? 245 ALA B C 1 ATOM 5436 O O . ALA B 1 237 ? 170.182 58.280 -90.403 1.00 17.07 ? 245 ALA B O 1 ATOM 5437 C CB . ALA B 1 237 ? 173.363 58.392 -90.253 1.00 17.50 ? 245 ALA B CB 1 ATOM 5438 N N . HIS B 1 238 ? 170.972 56.533 -89.219 1.00 17.21 ? 246 HIS B N 1 ATOM 5439 C CA . HIS B 1 238 ? 169.819 56.435 -88.335 1.00 17.24 ? 246 HIS B CA 1 ATOM 5440 C C . HIS B 1 238 ? 170.479 56.632 -86.974 1.00 18.77 ? 246 HIS B C 1 ATOM 5441 O O . HIS B 1 238 ? 171.299 55.814 -86.535 1.00 18.51 ? 246 HIS B O 1 ATOM 5442 C CB . HIS B 1 238 ? 169.172 55.064 -88.432 1.00 16.28 ? 246 HIS B CB 1 ATOM 5443 C CG . HIS B 1 238 ? 167.896 54.951 -87.669 1.00 19.50 ? 246 HIS B CG 1 ATOM 5444 N ND1 . HIS B 1 238 ? 166.777 54.325 -88.177 1.00 21.69 ? 246 HIS B ND1 1 ATOM 5445 C CD2 . HIS B 1 238 ? 167.560 55.365 -86.423 1.00 20.53 ? 246 HIS B CD2 1 ATOM 5446 C CE1 . HIS B 1 238 ? 165.809 54.356 -87.279 1.00 20.85 ? 246 HIS B CE1 1 ATOM 5447 N NE2 . HIS B 1 238 ? 166.258 54.983 -86.205 1.00 20.02 ? 246 HIS B NE2 1 ATOM 5448 N N . ILE B 1 239 ? 170.139 57.739 -86.328 1.00 19.34 ? 247 ILE B N 1 ATOM 5449 C CA . ILE B 1 239 ? 170.741 58.095 -85.061 1.00 19.18 ? 247 ILE B CA 1 ATOM 5450 C C . ILE B 1 239 ? 169.814 57.922 -83.878 1.00 19.87 ? 247 ILE B C 1 ATOM 5451 O O . ILE B 1 239 ? 168.687 58.415 -83.884 1.00 21.30 ? 247 ILE B O 1 ATOM 5452 C CB . ILE B 1 239 ? 171.226 59.540 -85.141 1.00 18.45 ? 247 ILE B CB 1 ATOM 5453 C CG1 . ILE B 1 239 ? 172.273 59.645 -86.255 1.00 18.04 ? 247 ILE B CG1 1 ATOM 5454 C CG2 . ILE B 1 239 ? 171.773 59.985 -83.799 1.00 17.35 ? 247 ILE B CG2 1 ATOM 5455 C CD1 . ILE B 1 239 ? 172.319 60.986 -86.951 1.00 18.22 ? 247 ILE B CD1 1 ATOM 5456 N N . ILE B 1 240 ? 170.301 57.215 -82.865 1.00 18.40 ? 248 ILE B N 1 ATOM 5457 C CA . ILE B 1 240 ? 169.523 56.970 -81.663 1.00 19.72 ? 248 ILE B CA 1 ATOM 5458 C C . ILE B 1 240 ? 170.187 57.683 -80.497 1.00 20.23 ? 248 ILE B C 1 ATOM 5459 O O . ILE B 1 240 ? 171.374 57.460 -80.221 1.00 21.41 ? 248 ILE B O 1 ATOM 5460 C CB . ILE B 1 240 ? 169.441 55.454 -81.348 1.00 19.71 ? 248 ILE B CB 1 ATOM 5461 C CG1 . ILE B 1 240 ? 168.652 54.734 -82.445 1.00 20.44 ? 248 ILE B CG1 1 ATOM 5462 C CG2 . ILE B 1 240 ? 168.775 55.236 -80.003 1.00 16.48 ? 248 ILE B CG2 1 ATOM 5463 C CD1 . ILE B 1 240 ? 168.664 53.225 -82.323 1.00 18.66 ? 248 ILE B CD1 1 ATOM 5464 N N . VAL B 1 241 ? 169.425 58.540 -79.819 1.00 18.91 ? 249 VAL B N 1 ATOM 5465 C CA . VAL B 1 241 ? 169.945 59.294 -78.681 1.00 16.60 ? 249 VAL B CA 1 ATOM 5466 C C . VAL B 1 241 ? 169.385 58.702 -77.394 1.00 16.21 ? 249 VAL B C 1 ATOM 5467 O O . VAL B 1 241 ? 168.174 58.535 -77.258 1.00 16.98 ? 249 VAL B O 1 ATOM 5468 C CB . VAL B 1 241 ? 169.550 60.794 -78.773 1.00 16.00 ? 249 VAL B CB 1 ATOM 5469 C CG1 . VAL B 1 241 ? 170.186 61.585 -77.638 1.00 15.04 ? 249 VAL B CG1 1 ATOM 5470 C CG2 . VAL B 1 241 ? 169.995 61.366 -80.113 1.00 15.44 ? 249 VAL B CG2 1 ATOM 5471 N N . LEU B 1 242 ? 170.270 58.374 -76.457 1.00 15.58 ? 250 LEU B N 1 ATOM 5472 C CA . LEU B 1 242 ? 169.854 57.807 -75.180 1.00 14.96 ? 250 LEU B CA 1 ATOM 5473 C C . LEU B 1 242 ? 170.169 58.751 -74.027 1.00 15.32 ? 250 LEU B C 1 ATOM 5474 O O . LEU B 1 242 ? 170.985 59.677 -74.160 1.00 14.34 ? 250 LEU B O 1 ATOM 5475 C CB . LEU B 1 242 ? 170.532 56.458 -74.953 1.00 16.11 ? 250 LEU B CB 1 ATOM 5476 C CG . LEU B 1 242 ? 170.141 55.406 -75.992 1.00 16.63 ? 250 LEU B CG 1 ATOM 5477 C CD1 . LEU B 1 242 ? 170.885 54.111 -75.745 1.00 15.37 ? 250 LEU B CD1 1 ATOM 5478 C CD2 . LEU B 1 242 ? 168.643 55.190 -75.924 1.00 15.14 ? 250 LEU B CD2 1 ATOM 5479 N N . SER B 1 243 ? 169.514 58.507 -72.897 1.00 14.44 ? 251 SER B N 1 ATOM 5480 C CA . SER B 1 243 ? 169.685 59.340 -71.723 1.00 13.30 ? 251 SER B CA 1 ATOM 5481 C C . SER B 1 243 ? 170.309 58.560 -70.571 1.00 14.60 ? 251 SER B C 1 ATOM 5482 O O . SER B 1 243 ? 169.641 57.758 -69.905 1.00 13.25 ? 251 SER B O 1 ATOM 5483 C CB . SER B 1 243 ? 168.331 59.890 -71.299 1.00 11.71 ? 251 SER B CB 1 ATOM 5484 O OG . SER B 1 243 ? 168.477 60.835 -70.263 1.00 11.40 ? 251 SER B OG 1 ATOM 5485 N N . SER B 1 244 ? 171.597 58.796 -70.343 1.00 15.85 ? 252 SER B N 1 ATOM 5486 C CA . SER B 1 244 ? 172.320 58.119 -69.281 1.00 15.89 ? 252 SER B CA 1 ATOM 5487 C C . SER B 1 244 ? 171.727 58.421 -67.914 1.00 16.56 ? 252 SER B C 1 ATOM 5488 O O . SER B 1 244 ? 171.873 57.625 -66.974 1.00 16.20 ? 252 SER B O 1 ATOM 5489 C CB . SER B 1 244 ? 173.792 58.552 -69.288 1.00 16.43 ? 252 SER B CB 1 ATOM 5490 O OG . SER B 1 244 ? 174.512 57.955 -70.353 1.00 20.32 ? 252 SER B OG 1 ATOM 5491 N N . TYR B 1 245 ? 171.053 59.561 -67.797 1.00 15.37 ? 253 TYR B N 1 ATOM 5492 C CA . TYR B 1 245 ? 170.521 59.943 -66.511 1.00 16.27 ? 253 TYR B CA 1 ATOM 5493 C C . TYR B 1 245 ? 169.006 59.902 -66.326 1.00 16.19 ? 253 TYR B C 1 ATOM 5494 O O . TYR B 1 245 ? 168.442 60.650 -65.523 1.00 16.38 ? 253 TYR B O 1 ATOM 5495 C CB . TYR B 1 245 ? 171.140 61.298 -66.126 1.00 15.24 ? 253 TYR B CB 1 ATOM 5496 C CG . TYR B 1 245 ? 172.658 61.228 -66.225 1.00 14.06 ? 253 TYR B CG 1 ATOM 5497 C CD1 . TYR B 1 245 ? 173.335 61.821 -67.287 1.00 12.82 ? 253 TYR B CD1 1 ATOM 5498 C CD2 . TYR B 1 245 ? 173.398 60.433 -65.340 1.00 13.31 ? 253 TYR B CD2 1 ATOM 5499 C CE1 . TYR B 1 245 ? 174.701 61.624 -67.470 1.00 12.92 ? 253 TYR B CE1 1 ATOM 5500 C CE2 . TYR B 1 245 ? 174.766 60.227 -65.522 1.00 12.49 ? 253 TYR B CE2 1 ATOM 5501 C CZ . TYR B 1 245 ? 175.406 60.826 -66.592 1.00 10.88 ? 253 TYR B CZ 1 ATOM 5502 O OH . TYR B 1 245 ? 176.747 60.629 -66.782 1.00 11.86 ? 253 TYR B OH 1 ATOM 5503 N N . SER B 1 246 ? 168.360 59.000 -67.062 1.00 15.03 ? 254 SER B N 1 ATOM 5504 C CA . SER B 1 246 ? 166.910 58.776 -66.964 1.00 15.30 ? 254 SER B CA 1 ATOM 5505 C C . SER B 1 246 ? 166.732 57.296 -66.612 1.00 16.01 ? 254 SER B C 1 ATOM 5506 O O . SER B 1 246 ? 167.679 56.517 -66.703 1.00 16.61 ? 254 SER B O 1 ATOM 5507 C CB . SER B 1 246 ? 166.207 59.040 -68.303 1.00 15.69 ? 254 SER B CB 1 ATOM 5508 O OG . SER B 1 246 ? 166.285 60.401 -68.686 1.00 15.70 ? 254 SER B OG 1 ATOM 5509 N N . ALA B 1 247 ? 165.527 56.898 -66.224 1.00 15.98 ? 255 ALA B N 1 ATOM 5510 C CA . ALA B 1 247 ? 165.294 55.502 -65.895 1.00 15.73 ? 255 ALA B CA 1 ATOM 5511 C C . ALA B 1 247 ? 165.513 54.647 -67.138 1.00 16.21 ? 255 ALA B C 1 ATOM 5512 O O . ALA B 1 247 ? 165.159 55.048 -68.236 1.00 15.39 ? 255 ALA B O 1 ATOM 5513 C CB . ALA B 1 247 ? 163.869 55.315 -65.388 1.00 15.93 ? 255 ALA B CB 1 ATOM 5514 N N . TYR B 1 248 ? 166.127 53.480 -66.977 1.00 17.60 ? 256 TYR B N 1 ATOM 5515 C CA . TYR B 1 248 ? 166.309 52.573 -68.105 1.00 17.98 ? 256 TYR B CA 1 ATOM 5516 C C . TYR B 1 248 ? 166.192 51.124 -67.653 1.00 18.43 ? 256 TYR B C 1 ATOM 5517 O O . TYR B 1 248 ? 166.775 50.216 -68.244 1.00 19.41 ? 256 TYR B O 1 ATOM 5518 C CB . TYR B 1 248 ? 167.635 52.818 -68.845 1.00 16.64 ? 256 TYR B CB 1 ATOM 5519 C CG . TYR B 1 248 ? 168.862 52.919 -67.981 1.00 16.47 ? 256 TYR B CG 1 ATOM 5520 C CD1 . TYR B 1 248 ? 169.368 51.810 -67.322 1.00 17.24 ? 256 TYR B CD1 1 ATOM 5521 C CD2 . TYR B 1 248 ? 169.503 54.140 -67.802 1.00 16.30 ? 256 TYR B CD2 1 ATOM 5522 C CE1 . TYR B 1 248 ? 170.486 51.914 -66.492 1.00 19.19 ? 256 TYR B CE1 1 ATOM 5523 C CE2 . TYR B 1 248 ? 170.612 54.255 -66.982 1.00 18.28 ? 256 TYR B CE2 1 ATOM 5524 C CZ . TYR B 1 248 ? 171.098 53.141 -66.324 1.00 19.17 ? 256 TYR B CZ 1 ATOM 5525 O OH . TYR B 1 248 ? 172.168 53.264 -65.461 1.00 21.25 ? 256 TYR B OH 1 ATOM 5526 N N . GLY B 1 249 ? 165.414 50.919 -66.596 1.00 18.45 ? 257 GLY B N 1 ATOM 5527 C CA . GLY B 1 249 ? 165.197 49.579 -66.092 1.00 18.00 ? 257 GLY B CA 1 ATOM 5528 C C . GLY B 1 249 ? 164.160 48.929 -66.988 1.00 19.56 ? 257 GLY B C 1 ATOM 5529 O O . GLY B 1 249 ? 163.503 49.611 -67.787 1.00 19.19 ? 257 GLY B O 1 ATOM 5530 N N . ARG B 1 250 ? 163.997 47.615 -66.868 1.00 19.94 ? 258 ARG B N 1 ATOM 5531 C CA . ARG B 1 250 ? 163.029 46.905 -67.699 1.00 19.55 ? 258 ARG B CA 1 ATOM 5532 C C . ARG B 1 250 ? 161.612 47.397 -67.421 1.00 18.65 ? 258 ARG B C 1 ATOM 5533 O O . ARG B 1 250 ? 161.185 47.470 -66.271 1.00 16.79 ? 258 ARG B O 1 ATOM 5534 C CB . ARG B 1 250 ? 163.133 45.407 -67.435 1.00 21.26 ? 258 ARG B CB 1 ATOM 5535 C CG . ARG B 1 250 ? 162.217 44.542 -68.274 1.00 23.37 ? 258 ARG B CG 1 ATOM 5536 C CD . ARG B 1 250 ? 162.644 43.089 -68.172 1.00 27.17 ? 258 ARG B CD 1 ATOM 5537 N NE . ARG B 1 250 ? 161.781 42.188 -68.930 1.00 33.19 ? 258 ARG B NE 1 ATOM 5538 C CZ . ARG B 1 250 ? 160.581 41.778 -68.523 1.00 37.78 ? 258 ARG B CZ 1 ATOM 5539 N NH1 . ARG B 1 250 ? 160.092 42.185 -67.352 1.00 40.21 ? 258 ARG B NH1 1 ATOM 5540 N NH2 . ARG B 1 250 ? 159.864 40.965 -69.289 1.00 39.69 ? 258 ARG B NH2 1 ATOM 5541 N N . GLY B 1 251 ? 160.892 47.743 -68.483 1.00 19.03 ? 259 GLY B N 1 ATOM 5542 C CA . GLY B 1 251 ? 159.527 48.221 -68.332 1.00 17.63 ? 259 GLY B CA 1 ATOM 5543 C C . GLY B 1 251 ? 159.410 49.736 -68.305 1.00 17.80 ? 259 GLY B C 1 ATOM 5544 O O . GLY B 1 251 ? 158.318 50.280 -68.480 1.00 17.43 ? 259 GLY B O 1 ATOM 5545 N N . THR B 1 252 ? 160.528 50.426 -68.085 1.00 16.89 ? 260 THR B N 1 ATOM 5546 C CA . THR B 1 252 ? 160.510 51.882 -68.038 1.00 14.54 ? 260 THR B CA 1 ATOM 5547 C C . THR B 1 252 ? 160.328 52.449 -69.433 1.00 14.44 ? 260 THR B C 1 ATOM 5548 O O . THR B 1 252 ? 160.676 51.813 -70.433 1.00 15.22 ? 260 THR B O 1 ATOM 5549 C CB . THR B 1 252 ? 161.817 52.457 -67.459 1.00 14.13 ? 260 THR B CB 1 ATOM 5550 O OG1 . THR B 1 252 ? 162.916 52.090 -68.305 1.00 14.34 ? 260 THR B OG1 1 ATOM 5551 C CG2 . THR B 1 252 ? 162.054 51.933 -66.052 1.00 11.42 ? 260 THR B CG2 1 ATOM 5552 N N . PRO B 1 253 ? 159.779 53.662 -69.520 1.00 13.35 ? 261 PRO B N 1 ATOM 5553 C CA . PRO B 1 253 ? 159.557 54.314 -70.810 1.00 13.45 ? 261 PRO B CA 1 ATOM 5554 C C . PRO B 1 253 ? 160.755 54.258 -71.767 1.00 13.88 ? 261 PRO B C 1 ATOM 5555 O O . PRO B 1 253 ? 160.596 53.881 -72.930 1.00 15.78 ? 261 PRO B O 1 ATOM 5556 C CB . PRO B 1 253 ? 159.200 55.741 -70.410 1.00 12.38 ? 261 PRO B CB 1 ATOM 5557 C CG . PRO B 1 253 ? 158.455 55.531 -69.136 1.00 13.10 ? 261 PRO B CG 1 ATOM 5558 C CD . PRO B 1 253 ? 159.303 54.507 -68.413 1.00 12.37 ? 261 PRO B CD 1 ATOM 5559 N N . GLN B 1 254 ? 161.946 54.628 -71.300 1.00 13.29 ? 262 GLN B N 1 ATOM 5560 C CA . GLN B 1 254 ? 163.103 54.609 -72.192 1.00 16.22 ? 262 GLN B CA 1 ATOM 5561 C C . GLN B 1 254 ? 163.453 53.203 -72.673 1.00 17.20 ? 262 GLN B C 1 ATOM 5562 O O . GLN B 1 254 ? 163.785 53.000 -73.846 1.00 16.66 ? 262 GLN B O 1 ATOM 5563 C CB . GLN B 1 254 ? 164.344 55.225 -71.527 1.00 17.32 ? 262 GLN B CB 1 ATOM 5564 C CG . GLN B 1 254 ? 165.511 55.377 -72.514 1.00 17.61 ? 262 GLN B CG 1 ATOM 5565 C CD . GLN B 1 254 ? 166.743 56.039 -71.922 1.00 18.59 ? 262 GLN B CD 1 ATOM 5566 O OE1 . GLN B 1 254 ? 167.632 56.491 -72.652 1.00 18.01 ? 262 GLN B OE1 1 ATOM 5567 N NE2 . GLN B 1 254 ? 166.811 56.091 -70.601 1.00 20.37 ? 262 GLN B NE2 1 ATOM 5568 N N . TYR B 1 255 ? 163.387 52.240 -71.760 1.00 16.96 ? 263 TYR B N 1 ATOM 5569 C CA . TYR B 1 255 ? 163.692 50.853 -72.070 1.00 17.37 ? 263 TYR B CA 1 ATOM 5570 C C . TYR B 1 255 ? 162.713 50.332 -73.129 1.00 18.67 ? 263 TYR B C 1 ATOM 5571 O O . TYR B 1 255 ? 163.116 49.741 -74.134 1.00 18.34 ? 263 TYR B O 1 ATOM 5572 C CB . TYR B 1 255 ? 163.606 50.035 -70.781 1.00 18.34 ? 263 TYR B CB 1 ATOM 5573 C CG . TYR B 1 255 ? 163.885 48.561 -70.929 1.00 19.33 ? 263 TYR B CG 1 ATOM 5574 C CD1 . TYR B 1 255 ? 162.932 47.701 -71.475 1.00 19.30 ? 263 TYR B CD1 1 ATOM 5575 C CD2 . TYR B 1 255 ? 165.097 48.017 -70.499 1.00 19.39 ? 263 TYR B CD2 1 ATOM 5576 C CE1 . TYR B 1 255 ? 163.175 46.336 -71.589 1.00 19.19 ? 263 TYR B CE1 1 ATOM 5577 C CE2 . TYR B 1 255 ? 165.351 46.654 -70.605 1.00 19.79 ? 263 TYR B CE2 1 ATOM 5578 C CZ . TYR B 1 255 ? 164.385 45.820 -71.153 1.00 21.08 ? 263 TYR B CZ 1 ATOM 5579 O OH . TYR B 1 255 ? 164.631 44.469 -71.279 1.00 21.98 ? 263 TYR B OH 1 ATOM 5580 N N . THR B 1 256 ? 161.426 50.573 -72.910 1.00 18.37 ? 264 THR B N 1 ATOM 5581 C CA . THR B 1 256 ? 160.405 50.137 -73.854 1.00 18.79 ? 264 THR B CA 1 ATOM 5582 C C . THR B 1 256 ? 160.600 50.780 -75.221 1.00 19.22 ? 264 THR B C 1 ATOM 5583 O O . THR B 1 256 ? 160.450 50.129 -76.255 1.00 20.30 ? 264 THR B O 1 ATOM 5584 C CB . THR B 1 256 ? 158.992 50.503 -73.356 1.00 18.17 ? 264 THR B CB 1 ATOM 5585 O OG1 . THR B 1 256 ? 158.752 49.862 -72.102 1.00 18.84 ? 264 THR B OG1 1 ATOM 5586 C CG2 . THR B 1 256 ? 157.932 50.041 -74.346 1.00 19.88 ? 264 THR B CG2 1 ATOM 5587 N N . TRP B 1 257 ? 160.924 52.064 -75.224 1.00 18.09 ? 265 TRP B N 1 ATOM 5588 C CA . TRP B 1 257 ? 161.111 52.776 -76.474 1.00 17.69 ? 265 TRP B CA 1 ATOM 5589 C C . TRP B 1 257 ? 162.303 52.242 -77.259 1.00 17.45 ? 265 TRP B C 1 ATOM 5590 O O . TRP B 1 257 ? 162.176 51.930 -78.438 1.00 18.62 ? 265 TRP B O 1 ATOM 5591 C CB . TRP B 1 257 ? 161.293 54.267 -76.200 1.00 18.00 ? 265 TRP B CB 1 ATOM 5592 C CG . TRP B 1 257 ? 161.519 55.071 -77.428 1.00 16.62 ? 265 TRP B CG 1 ATOM 5593 C CD1 . TRP B 1 257 ? 160.571 55.570 -78.267 1.00 16.51 ? 265 TRP B CD1 1 ATOM 5594 C CD2 . TRP B 1 257 ? 162.785 55.414 -77.997 1.00 17.44 ? 265 TRP B CD2 1 ATOM 5595 N NE1 . TRP B 1 257 ? 161.166 56.200 -79.334 1.00 16.25 ? 265 TRP B NE1 1 ATOM 5596 C CE2 . TRP B 1 257 ? 162.527 56.119 -79.194 1.00 16.60 ? 265 TRP B CE2 1 ATOM 5597 C CE3 . TRP B 1 257 ? 164.117 55.192 -77.613 1.00 17.36 ? 265 TRP B CE3 1 ATOM 5598 C CZ2 . TRP B 1 257 ? 163.553 56.607 -80.018 1.00 16.75 ? 265 TRP B CZ2 1 ATOM 5599 C CZ3 . TRP B 1 257 ? 165.140 55.676 -78.430 1.00 17.63 ? 265 TRP B CZ3 1 ATOM 5600 C CH2 . TRP B 1 257 ? 164.848 56.377 -79.621 1.00 17.09 ? 265 TRP B CH2 1 ATOM 5601 N N . LEU B 1 258 ? 163.457 52.133 -76.610 1.00 17.30 ? 266 LEU B N 1 ATOM 5602 C CA . LEU B 1 258 ? 164.659 51.642 -77.284 1.00 18.08 ? 266 LEU B CA 1 ATOM 5603 C C . LEU B 1 258 ? 164.459 50.267 -77.912 1.00 19.23 ? 266 LEU B C 1 ATOM 5604 O O . LEU B 1 258 ? 164.907 50.006 -79.031 1.00 18.33 ? 266 LEU B O 1 ATOM 5605 C CB . LEU B 1 258 ? 165.843 51.580 -76.307 1.00 15.04 ? 266 LEU B CB 1 ATOM 5606 C CG . LEU B 1 258 ? 167.158 51.094 -76.928 1.00 11.41 ? 266 LEU B CG 1 ATOM 5607 C CD1 . LEU B 1 258 ? 167.549 51.973 -78.108 1.00 8.31 ? 266 LEU B CD1 1 ATOM 5608 C CD2 . LEU B 1 258 ? 168.243 51.111 -75.880 1.00 12.34 ? 266 LEU B CD2 1 ATOM 5609 N N . LYS B 1 259 ? 163.781 49.389 -77.187 1.00 21.88 ? 267 LYS B N 1 ATOM 5610 C CA . LYS B 1 259 ? 163.530 48.039 -77.671 1.00 24.39 ? 267 LYS B CA 1 ATOM 5611 C C . LYS B 1 259 ? 162.720 48.040 -78.968 1.00 24.14 ? 267 LYS B C 1 ATOM 5612 O O . LYS B 1 259 ? 163.045 47.309 -79.900 1.00 24.13 ? 267 LYS B O 1 ATOM 5613 C CB . LYS B 1 259 ? 162.802 47.237 -76.602 1.00 26.60 ? 267 LYS B CB 1 ATOM 5614 C CG . LYS B 1 259 ? 162.787 45.746 -76.841 1.00 30.33 ? 267 LYS B CG 1 ATOM 5615 C CD . LYS B 1 259 ? 161.969 45.068 -75.766 1.00 34.77 ? 267 LYS B CD 1 ATOM 5616 C CE . LYS B 1 259 ? 161.820 43.588 -76.037 1.00 39.24 ? 267 LYS B CE 1 ATOM 5617 N NZ . LYS B 1 259 ? 160.802 43.005 -75.117 1.00 42.65 ? 267 LYS B NZ 1 ATOM 5618 N N . LYS B 1 260 ? 161.673 48.857 -79.029 1.00 24.62 ? 268 LYS B N 1 ATOM 5619 C CA . LYS B 1 260 ? 160.844 48.940 -80.229 1.00 26.69 ? 268 LYS B CA 1 ATOM 5620 C C . LYS B 1 260 ? 161.555 49.684 -81.362 1.00 26.65 ? 268 LYS B C 1 ATOM 5621 O O . LYS B 1 260 ? 161.393 49.351 -82.533 1.00 26.45 ? 268 LYS B O 1 ATOM 5622 C CB . LYS B 1 260 ? 159.527 49.656 -79.923 1.00 29.55 ? 268 LYS B CB 1 ATOM 5623 C CG . LYS B 1 260 ? 158.612 48.911 -78.966 1.00 38.16 ? 268 LYS B CG 1 ATOM 5624 C CD . LYS B 1 260 ? 157.346 49.727 -78.685 1.00 43.63 ? 268 LYS B CD 1 ATOM 5625 C CE . LYS B 1 260 ? 156.429 49.044 -77.672 1.00 45.50 ? 268 LYS B CE 1 ATOM 5626 N NZ . LYS B 1 260 ? 155.313 49.954 -77.260 1.00 47.12 ? 268 LYS B NZ 1 ATOM 5627 N N . GLU B 1 261 ? 162.336 50.696 -81.003 1.00 25.79 ? 269 GLU B N 1 ATOM 5628 C CA . GLU B 1 261 ? 163.053 51.499 -81.982 1.00 23.56 ? 269 GLU B CA 1 ATOM 5629 C C . GLU B 1 261 ? 164.080 50.699 -82.767 1.00 23.56 ? 269 GLU B C 1 ATOM 5630 O O . GLU B 1 261 ? 164.242 50.906 -83.967 1.00 23.11 ? 269 GLU B O 1 ATOM 5631 C CB . GLU B 1 261 ? 163.743 52.668 -81.285 1.00 23.20 ? 269 GLU B CB 1 ATOM 5632 C CG . GLU B 1 261 ? 164.409 53.653 -82.228 1.00 23.75 ? 269 GLU B CG 1 ATOM 5633 C CD . GLU B 1 261 ? 163.452 54.209 -83.269 1.00 24.09 ? 269 GLU B CD 1 ATOM 5634 O OE1 . GLU B 1 261 ? 162.220 54.143 -83.059 1.00 24.82 ? 269 GLU B OE1 1 ATOM 5635 O OE2 . GLU B 1 261 ? 163.934 54.726 -84.296 1.00 24.03 ? 269 GLU B OE2 1 ATOM 5636 N N . LEU B 1 262 ? 164.783 49.794 -82.094 1.00 23.49 ? 270 LEU B N 1 ATOM 5637 C CA . LEU B 1 262 ? 165.788 48.984 -82.772 1.00 24.79 ? 270 LEU B CA 1 ATOM 5638 C C . LEU B 1 262 ? 165.149 48.073 -83.815 1.00 27.34 ? 270 LEU B C 1 ATOM 5639 O O . LEU B 1 262 ? 165.723 47.846 -84.880 1.00 26.53 ? 270 LEU B O 1 ATOM 5640 C CB . LEU B 1 262 ? 166.585 48.158 -81.763 1.00 21.92 ? 270 LEU B CB 1 ATOM 5641 C CG . LEU B 1 262 ? 167.624 48.952 -80.967 1.00 19.82 ? 270 LEU B CG 1 ATOM 5642 C CD1 . LEU B 1 262 ? 168.163 48.098 -79.837 1.00 20.51 ? 270 LEU B CD1 1 ATOM 5643 C CD2 . LEU B 1 262 ? 168.750 49.400 -81.886 1.00 17.40 ? 270 LEU B CD2 1 ATOM 5644 N N . ARG B 1 263 ? 163.961 47.553 -83.509 1.00 30.17 ? 271 ARG B N 1 ATOM 5645 C CA . ARG B 1 263 ? 163.259 46.686 -84.450 1.00 33.14 ? 271 ARG B CA 1 ATOM 5646 C C . ARG B 1 263 ? 162.871 47.463 -85.701 1.00 32.39 ? 271 ARG B C 1 ATOM 5647 O O . ARG B 1 263 ? 162.728 46.883 -86.772 1.00 32.89 ? 271 ARG B O 1 ATOM 5648 C CB . ARG B 1 263 ? 161.988 46.085 -83.828 1.00 36.07 ? 271 ARG B CB 1 ATOM 5649 C CG . ARG B 1 263 ? 162.241 44.976 -82.824 1.00 43.14 ? 271 ARG B CG 1 ATOM 5650 C CD . ARG B 1 263 ? 160.959 44.194 -82.499 1.00 49.95 ? 271 ARG B CD 1 ATOM 5651 N NE . ARG B 1 263 ? 161.206 43.128 -81.521 1.00 56.54 ? 271 ARG B NE 1 ATOM 5652 C CZ . ARG B 1 263 ? 161.085 43.267 -80.199 1.00 58.64 ? 271 ARG B CZ 1 ATOM 5653 N NH1 . ARG B 1 263 ? 160.703 44.432 -79.679 1.00 59.46 ? 271 ARG B NH1 1 ATOM 5654 N NH2 . ARG B 1 263 ? 161.373 42.251 -79.390 1.00 58.73 ? 271 ARG B NH2 1 ATOM 5655 N N . LYS B 1 264 ? 162.709 48.776 -85.567 1.00 31.44 ? 272 LYS B N 1 ATOM 5656 C CA . LYS B 1 264 ? 162.317 49.604 -86.700 1.00 30.61 ? 272 LYS B CA 1 ATOM 5657 C C . LYS B 1 264 ? 163.465 50.086 -87.582 1.00 30.06 ? 272 LYS B C 1 ATOM 5658 O O . LYS B 1 264 ? 163.233 50.717 -88.608 1.00 31.64 ? 272 LYS B O 1 ATOM 5659 C CB . LYS B 1 264 ? 161.497 50.803 -86.214 1.00 31.29 ? 272 LYS B CB 1 ATOM 5660 C CG . LYS B 1 264 ? 160.181 50.407 -85.550 1.00 35.63 ? 272 LYS B CG 1 ATOM 5661 C CD . LYS B 1 264 ? 159.253 51.598 -85.315 1.00 39.35 ? 272 LYS B CD 1 ATOM 5662 C CE . LYS B 1 264 ? 159.828 52.583 -84.306 1.00 44.61 ? 272 LYS B CE 1 ATOM 5663 N NZ . LYS B 1 264 ? 158.908 53.737 -84.039 1.00 47.66 ? 272 LYS B NZ 1 ATOM 5664 N N . VAL B 1 265 ? 164.703 49.794 -87.211 1.00 29.12 ? 273 VAL B N 1 ATOM 5665 C CA . VAL B 1 265 ? 165.807 50.244 -88.048 1.00 28.44 ? 273 VAL B CA 1 ATOM 5666 C C . VAL B 1 265 ? 165.865 49.415 -89.335 1.00 28.74 ? 273 VAL B C 1 ATOM 5667 O O . VAL B 1 265 ? 165.718 48.188 -89.310 1.00 28.22 ? 273 VAL B O 1 ATOM 5668 C CB . VAL B 1 265 ? 167.172 50.158 -87.304 1.00 26.72 ? 273 VAL B CB 1 ATOM 5669 C CG1 . VAL B 1 265 ? 168.281 50.730 -88.175 1.00 23.51 ? 273 VAL B CG1 1 ATOM 5670 C CG2 . VAL B 1 265 ? 167.102 50.927 -85.995 1.00 23.58 ? 273 VAL B CG2 1 ATOM 5671 N N . LYS B 1 266 ? 166.048 50.105 -90.456 1.00 29.11 ? 274 LYS B N 1 ATOM 5672 C CA . LYS B 1 266 ? 166.146 49.472 -91.767 1.00 29.78 ? 274 LYS B CA 1 ATOM 5673 C C . LYS B 1 266 ? 167.513 49.804 -92.360 1.00 28.50 ? 274 LYS B C 1 ATOM 5674 O O . LYS B 1 266 ? 167.757 50.934 -92.794 1.00 26.99 ? 274 LYS B O 1 ATOM 5675 C CB . LYS B 1 266 ? 165.049 50.000 -92.691 1.00 33.91 ? 274 LYS B CB 1 ATOM 5676 C CG . LYS B 1 266 ? 163.660 49.486 -92.379 1.00 40.40 ? 274 LYS B CG 1 ATOM 5677 C CD . LYS B 1 266 ? 162.603 50.307 -93.113 1.00 46.80 ? 274 LYS B CD 1 ATOM 5678 C CE . LYS B 1 266 ? 162.864 50.368 -94.623 1.00 50.03 ? 274 LYS B CE 1 ATOM 5679 N NZ . LYS B 1 266 ? 161.817 51.163 -95.343 1.00 52.23 ? 274 LYS B NZ 1 ATOM 5680 N N . ARG B 1 267 ? 168.401 48.819 -92.370 1.00 28.02 ? 275 ARG B N 1 ATOM 5681 C CA . ARG B 1 267 ? 169.744 49.008 -92.898 1.00 28.31 ? 275 ARG B CA 1 ATOM 5682 C C . ARG B 1 267 ? 169.767 49.196 -94.404 1.00 29.22 ? 275 ARG B C 1 ATOM 5683 O O . ARG B 1 267 ? 170.771 49.636 -94.970 1.00 29.08 ? 275 ARG B O 1 ATOM 5684 C CB . ARG B 1 267 ? 170.605 47.819 -92.523 1.00 27.45 ? 275 ARG B CB 1 ATOM 5685 C CG . ARG B 1 267 ? 170.763 47.683 -91.049 1.00 25.71 ? 275 ARG B CG 1 ATOM 5686 C CD . ARG B 1 267 ? 171.606 48.806 -90.482 1.00 23.75 ? 275 ARG B CD 1 ATOM 5687 N NE . ARG B 1 267 ? 172.228 48.290 -89.282 1.00 25.12 ? 275 ARG B NE 1 ATOM 5688 C CZ . ARG B 1 267 ? 173.500 48.448 -88.957 1.00 25.24 ? 275 ARG B CZ 1 ATOM 5689 N NH1 . ARG B 1 267 ? 174.326 49.131 -89.732 1.00 24.16 ? 275 ARG B NH1 1 ATOM 5690 N NH2 . ARG B 1 267 ? 173.950 47.873 -87.862 1.00 29.55 ? 275 ARG B NH2 1 ATOM 5691 N N . SER B 1 268 ? 168.657 48.852 -95.044 1.00 29.23 ? 276 SER B N 1 ATOM 5692 C CA . SER B 1 268 ? 168.524 48.985 -96.483 1.00 30.26 ? 276 SER B CA 1 ATOM 5693 C C . SER B 1 268 ? 168.147 50.419 -96.846 1.00 30.70 ? 276 SER B C 1 ATOM 5694 O O . SER B 1 268 ? 168.326 50.837 -97.989 1.00 31.53 ? 276 SER B O 1 ATOM 5695 C CB . SER B 1 268 ? 167.468 48.007 -96.990 1.00 30.82 ? 276 SER B CB 1 ATOM 5696 O OG . SER B 1 268 ? 166.372 47.951 -96.090 1.00 35.39 ? 276 SER B OG 1 ATOM 5697 N N . GLU B 1 269 ? 167.626 51.167 -95.873 1.00 31.13 ? 277 GLU B N 1 ATOM 5698 C CA . GLU B 1 269 ? 167.241 52.559 -96.095 1.00 31.48 ? 277 GLU B CA 1 ATOM 5699 C C . GLU B 1 269 ? 168.312 53.483 -95.507 1.00 30.21 ? 277 GLU B C 1 ATOM 5700 O O . GLU B 1 269 ? 168.638 54.519 -96.094 1.00 31.23 ? 277 GLU B O 1 ATOM 5701 C CB . GLU B 1 269 ? 165.879 52.866 -95.453 1.00 35.25 ? 277 GLU B CB 1 ATOM 5702 C CG . GLU B 1 269 ? 165.352 54.277 -95.786 1.00 43.75 ? 277 GLU B CG 1 ATOM 5703 C CD . GLU B 1 269 ? 164.066 54.653 -95.040 1.00 48.98 ? 277 GLU B CD 1 ATOM 5704 O OE1 . GLU B 1 269 ? 163.121 53.829 -95.017 1.00 52.83 ? 277 GLU B OE1 1 ATOM 5705 O OE2 . GLU B 1 269 ? 163.997 55.777 -94.486 1.00 49.76 ? 277 GLU B OE2 1 ATOM 5706 N N . THR B 1 270 ? 168.844 53.111 -94.342 1.00 27.76 ? 278 THR B N 1 ATOM 5707 C CA . THR B 1 270 ? 169.896 53.879 -93.669 1.00 25.36 ? 278 THR B CA 1 ATOM 5708 C C . THR B 1 270 ? 170.917 52.870 -93.157 1.00 25.24 ? 278 THR B C 1 ATOM 5709 O O . THR B 1 270 ? 170.759 52.310 -92.078 1.00 25.73 ? 278 THR B O 1 ATOM 5710 C CB . THR B 1 270 ? 169.356 54.680 -92.461 1.00 23.67 ? 278 THR B CB 1 ATOM 5711 O OG1 . THR B 1 270 ? 168.613 53.809 -91.600 1.00 22.41 ? 278 THR B OG1 1 ATOM 5712 C CG2 . THR B 1 270 ? 168.468 55.818 -92.921 1.00 23.33 ? 278 THR B CG2 1 ATOM 5713 N N . PRO B 1 271 ? 171.986 52.626 -93.927 1.00 24.84 ? 279 PRO B N 1 ATOM 5714 C CA . PRO B 1 271 ? 173.028 51.670 -93.541 1.00 23.72 ? 279 PRO B CA 1 ATOM 5715 C C . PRO B 1 271 ? 173.799 51.950 -92.246 1.00 23.87 ? 279 PRO B C 1 ATOM 5716 O O . PRO B 1 271 ? 174.168 51.022 -91.522 1.00 23.67 ? 279 PRO B O 1 ATOM 5717 C CB . PRO B 1 271 ? 173.935 51.647 -94.771 1.00 23.26 ? 279 PRO B CB 1 ATOM 5718 C CG . PRO B 1 271 ? 173.810 53.030 -95.292 1.00 24.24 ? 279 PRO B CG 1 ATOM 5719 C CD . PRO B 1 271 ? 172.328 53.281 -95.201 1.00 24.16 ? 279 PRO B CD 1 ATOM 5720 N N . TRP B 1 272 ? 174.050 53.215 -91.941 1.00 22.98 ? 280 TRP B N 1 ATOM 5721 C CA . TRP B 1 272 ? 174.792 53.512 -90.728 1.00 21.62 ? 280 TRP B CA 1 ATOM 5722 C C . TRP B 1 272 ? 173.893 53.703 -89.526 1.00 20.87 ? 280 TRP B C 1 ATOM 5723 O O . TRP B 1 272 ? 172.990 54.551 -89.534 1.00 20.69 ? 280 TRP B O 1 ATOM 5724 C CB . TRP B 1 272 ? 175.671 54.739 -90.943 1.00 21.48 ? 280 TRP B CB 1 ATOM 5725 C CG . TRP B 1 272 ? 176.621 54.508 -92.068 1.00 20.63 ? 280 TRP B CG 1 ATOM 5726 C CD1 . TRP B 1 272 ? 176.433 54.828 -93.381 1.00 19.16 ? 280 TRP B CD1 1 ATOM 5727 C CD2 . TRP B 1 272 ? 177.859 53.793 -92.003 1.00 20.72 ? 280 TRP B CD2 1 ATOM 5728 N NE1 . TRP B 1 272 ? 177.474 54.354 -94.139 1.00 19.85 ? 280 TRP B NE1 1 ATOM 5729 C CE2 . TRP B 1 272 ? 178.365 53.713 -93.316 1.00 20.60 ? 280 TRP B CE2 1 ATOM 5730 C CE3 . TRP B 1 272 ? 178.590 53.207 -90.958 1.00 20.12 ? 280 TRP B CE3 1 ATOM 5731 C CZ2 . TRP B 1 272 ? 179.568 53.069 -93.617 1.00 20.57 ? 280 TRP B CZ2 1 ATOM 5732 C CZ3 . TRP B 1 272 ? 179.783 52.569 -91.254 1.00 18.91 ? 280 TRP B CZ3 1 ATOM 5733 C CH2 . TRP B 1 272 ? 180.261 52.506 -92.575 1.00 20.91 ? 280 TRP B CH2 1 ATOM 5734 N N . LEU B 1 273 ? 174.139 52.891 -88.500 1.00 19.26 ? 281 LEU B N 1 ATOM 5735 C CA . LEU B 1 273 ? 173.367 52.943 -87.264 1.00 19.19 ? 281 LEU B CA 1 ATOM 5736 C C . LEU B 1 273 ? 174.250 53.483 -86.135 1.00 19.71 ? 281 LEU B C 1 ATOM 5737 O O . LEU B 1 273 ? 175.200 52.816 -85.681 1.00 18.27 ? 281 LEU B O 1 ATOM 5738 C CB . LEU B 1 273 ? 172.849 51.547 -86.910 1.00 17.80 ? 281 LEU B CB 1 ATOM 5739 C CG . LEU B 1 273 ? 172.117 51.416 -85.573 1.00 17.85 ? 281 LEU B CG 1 ATOM 5740 C CD1 . LEU B 1 273 ? 170.938 52.388 -85.532 1.00 17.95 ? 281 LEU B CD1 1 ATOM 5741 C CD2 . LEU B 1 273 ? 171.643 49.986 -85.391 1.00 15.05 ? 281 LEU B CD2 1 ATOM 5742 N N . ILE B 1 274 ? 173.915 54.690 -85.682 1.00 18.86 ? 282 ILE B N 1 ATOM 5743 C CA . ILE B 1 274 ? 174.669 55.364 -84.638 1.00 18.70 ? 282 ILE B CA 1 ATOM 5744 C C . ILE B 1 274 ? 173.882 55.550 -83.344 1.00 18.66 ? 282 ILE B C 1 ATOM 5745 O O . ILE B 1 274 ? 172.681 55.827 -83.371 1.00 20.75 ? 282 ILE B O 1 ATOM 5746 C CB . ILE B 1 274 ? 175.111 56.754 -85.124 1.00 18.27 ? 282 ILE B CB 1 ATOM 5747 C CG1 . ILE B 1 274 ? 175.801 56.627 -86.484 1.00 17.62 ? 282 ILE B CG1 1 ATOM 5748 C CG2 . ILE B 1 274 ? 176.057 57.386 -84.111 1.00 18.85 ? 282 ILE B CG2 1 ATOM 5749 C CD1 . ILE B 1 274 ? 176.201 57.942 -87.086 1.00 19.27 ? 282 ILE B CD1 1 ATOM 5750 N N . VAL B 1 275 ? 174.569 55.406 -82.212 1.00 17.82 ? 283 VAL B N 1 ATOM 5751 C CA . VAL B 1 275 ? 173.954 55.595 -80.902 1.00 18.13 ? 283 VAL B CA 1 ATOM 5752 C C . VAL B 1 275 ? 174.740 56.641 -80.118 1.00 17.22 ? 283 VAL B C 1 ATOM 5753 O O . VAL B 1 275 ? 175.970 56.594 -80.060 1.00 16.78 ? 283 VAL B O 1 ATOM 5754 C CB . VAL B 1 275 ? 173.942 54.294 -80.069 1.00 18.06 ? 283 VAL B CB 1 ATOM 5755 C CG1 . VAL B 1 275 ? 173.384 54.578 -78.679 1.00 14.10 ? 283 VAL B CG1 1 ATOM 5756 C CG2 . VAL B 1 275 ? 173.105 53.234 -80.767 1.00 16.92 ? 283 VAL B CG2 1 ATOM 5757 N N . LEU B 1 276 ? 174.024 57.587 -79.521 1.00 16.76 ? 284 LEU B N 1 ATOM 5758 C CA . LEU B 1 276 ? 174.644 58.641 -78.717 1.00 15.57 ? 284 LEU B CA 1 ATOM 5759 C C . LEU B 1 276 ? 174.123 58.531 -77.282 1.00 14.50 ? 284 LEU B C 1 ATOM 5760 O O . LEU B 1 276 ? 172.949 58.231 -77.062 1.00 14.13 ? 284 LEU B O 1 ATOM 5761 C CB . LEU B 1 276 ? 174.282 60.024 -79.268 1.00 14.09 ? 284 LEU B CB 1 ATOM 5762 C CG . LEU B 1 276 ? 174.490 60.335 -80.750 1.00 15.44 ? 284 LEU B CG 1 ATOM 5763 C CD1 . LEU B 1 276 ? 173.988 61.749 -81.054 1.00 15.11 ? 284 LEU B CD1 1 ATOM 5764 C CD2 . LEU B 1 276 ? 175.958 60.205 -81.111 1.00 15.13 ? 284 LEU B CD2 1 ATOM 5765 N N . MET B 1 277 ? 175.005 58.770 -76.317 1.00 15.13 ? 285 MET B N 1 ATOM 5766 C CA . MET B 1 277 ? 174.673 58.732 -74.888 1.00 15.40 ? 285 MET B CA 1 ATOM 5767 C C . MET B 1 277 ? 175.786 59.518 -74.209 1.00 16.52 ? 285 MET B C 1 ATOM 5768 O O . MET B 1 277 ? 176.900 59.586 -74.735 1.00 16.47 ? 285 MET B O 1 ATOM 5769 C CB . MET B 1 277 ? 174.664 57.296 -74.379 1.00 13.12 ? 285 MET B CB 1 ATOM 5770 C CG . MET B 1 277 ? 175.906 56.524 -74.748 1.00 15.31 ? 285 MET B CG 1 ATOM 5771 S SD . MET B 1 277 ? 175.916 54.895 -74.015 1.00 17.46 ? 285 MET B SD 1 ATOM 5772 C CE . MET B 1 277 ? 174.781 54.036 -75.079 1.00 14.53 ? 285 MET B CE 1 ATOM 5773 N N . HIS B 1 278 ? 175.514 60.117 -73.054 1.00 16.88 ? 286 HIS B N 1 ATOM 5774 C CA . HIS B 1 278 ? 176.565 60.885 -72.406 1.00 15.48 ? 286 HIS B CA 1 ATOM 5775 C C . HIS B 1 278 ? 177.632 60.049 -71.703 1.00 14.34 ? 286 HIS B C 1 ATOM 5776 O O . HIS B 1 278 ? 178.814 60.311 -71.877 1.00 14.07 ? 286 HIS B O 1 ATOM 5777 C CB . HIS B 1 278 ? 175.979 61.900 -71.425 1.00 16.12 ? 286 HIS B CB 1 ATOM 5778 C CG . HIS B 1 278 ? 177.016 62.791 -70.812 1.00 16.56 ? 286 HIS B CG 1 ATOM 5779 N ND1 . HIS B 1 278 ? 177.794 63.645 -71.561 1.00 16.09 ? 286 HIS B ND1 1 ATOM 5780 C CD2 . HIS B 1 278 ? 177.443 62.911 -69.532 1.00 15.18 ? 286 HIS B CD2 1 ATOM 5781 C CE1 . HIS B 1 278 ? 178.662 64.253 -70.768 1.00 15.67 ? 286 HIS B CE1 1 ATOM 5782 N NE2 . HIS B 1 278 ? 178.470 63.825 -69.536 1.00 16.42 ? 286 HIS B NE2 1 ATOM 5783 N N . SER B 1 279 ? 177.237 59.048 -70.924 1.00 13.98 ? 287 SER B N 1 ATOM 5784 C CA . SER B 1 279 ? 178.223 58.228 -70.213 1.00 16.03 ? 287 SER B CA 1 ATOM 5785 C C . SER B 1 279 ? 178.675 56.994 -71.010 1.00 16.16 ? 287 SER B C 1 ATOM 5786 O O . SER B 1 279 ? 177.862 56.145 -71.372 1.00 18.81 ? 287 SER B O 1 ATOM 5787 C CB . SER B 1 279 ? 177.653 57.788 -68.866 1.00 16.50 ? 287 SER B CB 1 ATOM 5788 O OG . SER B 1 279 ? 178.666 57.202 -68.071 1.00 19.03 ? 287 SER B OG 1 ATOM 5789 N N . PRO B 1 280 ? 179.986 56.872 -71.271 1.00 16.62 ? 288 PRO B N 1 ATOM 5790 C CA . PRO B 1 280 ? 180.543 55.747 -72.031 1.00 16.96 ? 288 PRO B CA 1 ATOM 5791 C C . PRO B 1 280 ? 180.426 54.373 -71.373 1.00 18.09 ? 288 PRO B C 1 ATOM 5792 O O . PRO B 1 280 ? 180.622 54.236 -70.167 1.00 18.58 ? 288 PRO B O 1 ATOM 5793 C CB . PRO B 1 280 ? 181.993 56.163 -72.230 1.00 16.56 ? 288 PRO B CB 1 ATOM 5794 C CG . PRO B 1 280 ? 182.296 56.885 -70.938 1.00 16.47 ? 288 PRO B CG 1 ATOM 5795 C CD . PRO B 1 280 ? 181.061 57.744 -70.759 1.00 16.34 ? 288 PRO B CD 1 ATOM 5796 N N . LEU B 1 281 ? 180.115 53.358 -72.179 1.00 18.39 ? 289 LEU B N 1 ATOM 5797 C CA . LEU B 1 281 ? 179.986 51.994 -71.674 1.00 18.20 ? 289 LEU B CA 1 ATOM 5798 C C . LEU B 1 281 ? 181.371 51.346 -71.559 1.00 18.19 ? 289 LEU B C 1 ATOM 5799 O O . LEU B 1 281 ? 181.580 50.422 -70.766 1.00 17.34 ? 289 LEU B O 1 ATOM 5800 C CB . LEU B 1 281 ? 179.076 51.170 -72.589 1.00 17.66 ? 289 LEU B CB 1 ATOM 5801 C CG . LEU B 1 281 ? 177.687 51.757 -72.864 1.00 18.16 ? 289 LEU B CG 1 ATOM 5802 C CD1 . LEU B 1 281 ? 176.830 50.721 -73.575 1.00 18.37 ? 289 LEU B CD1 1 ATOM 5803 C CD2 . LEU B 1 281 ? 177.031 52.178 -71.558 1.00 17.76 ? 289 LEU B CD2 1 ATOM 5804 N N . TYR B 1 282 ? 182.308 51.831 -72.368 1.00 16.78 ? 290 TYR B N 1 ATOM 5805 C CA . TYR B 1 282 ? 183.681 51.353 -72.326 1.00 18.14 ? 290 TYR B CA 1 ATOM 5806 C C . TYR B 1 282 ? 184.539 52.583 -72.099 1.00 19.33 ? 290 TYR B C 1 ATOM 5807 O O . TYR B 1 282 ? 184.445 53.562 -72.838 1.00 19.87 ? 290 TYR B O 1 ATOM 5808 C CB . TYR B 1 282 ? 184.051 50.648 -73.623 1.00 17.45 ? 290 TYR B CB 1 ATOM 5809 C CG . TYR B 1 282 ? 183.549 49.236 -73.648 1.00 15.40 ? 290 TYR B CG 1 ATOM 5810 C CD1 . TYR B 1 282 ? 184.318 48.192 -73.126 1.00 15.57 ? 290 TYR B CD1 1 ATOM 5811 C CD2 . TYR B 1 282 ? 182.282 48.944 -74.143 1.00 15.06 ? 290 TYR B CD2 1 ATOM 5812 C CE1 . TYR B 1 282 ? 183.834 46.888 -73.097 1.00 14.76 ? 290 TYR B CE1 1 ATOM 5813 C CE2 . TYR B 1 282 ? 181.783 47.643 -74.120 1.00 15.35 ? 290 TYR B CE2 1 ATOM 5814 C CZ . TYR B 1 282 ? 182.564 46.625 -73.596 1.00 16.33 ? 290 TYR B CZ 1 ATOM 5815 O OH . TYR B 1 282 ? 182.064 45.350 -73.579 1.00 17.82 ? 290 TYR B OH 1 ATOM 5816 N N . ASN B 1 283 ? 185.364 52.528 -71.060 1.00 20.14 ? 291 ASN B N 1 ATOM 5817 C CA . ASN B 1 283 ? 186.204 53.650 -70.678 1.00 20.95 ? 291 ASN B CA 1 ATOM 5818 C C . ASN B 1 283 ? 187.392 53.164 -69.860 1.00 22.05 ? 291 ASN B C 1 ATOM 5819 O O . ASN B 1 283 ? 187.210 52.531 -68.822 1.00 21.79 ? 291 ASN B O 1 ATOM 5820 C CB . ASN B 1 283 ? 185.366 54.608 -69.837 1.00 21.02 ? 291 ASN B CB 1 ATOM 5821 C CG . ASN B 1 283 ? 186.188 55.682 -69.180 1.00 22.20 ? 291 ASN B CG 1 ATOM 5822 O OD1 . ASN B 1 283 ? 185.783 56.232 -68.157 1.00 24.60 ? 291 ASN B OD1 1 ATOM 5823 N ND2 . ASN B 1 283 ? 187.338 56.002 -69.763 1.00 21.82 ? 291 ASN B ND2 1 ATOM 5824 N N . SER B 1 284 ? 188.607 53.461 -70.313 1.00 22.97 ? 292 SER B N 1 ATOM 5825 C CA . SER B 1 284 ? 189.785 53.029 -69.576 1.00 24.03 ? 292 SER B CA 1 ATOM 5826 C C . SER B 1 284 ? 190.488 54.163 -68.830 1.00 25.26 ? 292 SER B C 1 ATOM 5827 O O . SER B 1 284 ? 191.667 54.058 -68.507 1.00 26.30 ? 292 SER B O 1 ATOM 5828 C CB . SER B 1 284 ? 190.778 52.318 -70.502 1.00 23.72 ? 292 SER B CB 1 ATOM 5829 O OG . SER B 1 284 ? 191.364 53.216 -71.423 1.00 24.39 ? 292 SER B OG 1 ATOM 5830 N N . TYR B 1 285 ? 189.772 55.252 -68.567 1.00 24.64 ? 293 TYR B N 1 ATOM 5831 C CA . TYR B 1 285 ? 190.342 56.366 -67.807 1.00 23.51 ? 293 TYR B CA 1 ATOM 5832 C C . TYR B 1 285 ? 189.868 56.216 -66.370 1.00 25.01 ? 293 TYR B C 1 ATOM 5833 O O . TYR B 1 285 ? 188.846 55.577 -66.114 1.00 23.44 ? 293 TYR B O 1 ATOM 5834 C CB . TYR B 1 285 ? 189.865 57.712 -68.337 1.00 21.10 ? 293 TYR B CB 1 ATOM 5835 C CG . TYR B 1 285 ? 190.554 58.155 -69.598 1.00 21.81 ? 293 TYR B CG 1 ATOM 5836 C CD1 . TYR B 1 285 ? 190.249 57.572 -70.823 1.00 21.69 ? 293 TYR B CD1 1 ATOM 5837 C CD2 . TYR B 1 285 ? 191.509 59.170 -69.570 1.00 21.52 ? 293 TYR B CD2 1 ATOM 5838 C CE1 . TYR B 1 285 ? 190.877 57.992 -71.991 1.00 21.26 ? 293 TYR B CE1 1 ATOM 5839 C CE2 . TYR B 1 285 ? 192.139 59.596 -70.729 1.00 20.10 ? 293 TYR B CE2 1 ATOM 5840 C CZ . TYR B 1 285 ? 191.816 59.005 -71.935 1.00 21.28 ? 293 TYR B CZ 1 ATOM 5841 O OH . TYR B 1 285 ? 192.402 59.444 -73.098 1.00 22.73 ? 293 TYR B OH 1 ATOM 5842 N N . ASN B 1 286 ? 190.601 56.797 -65.428 1.00 25.98 ? 294 ASN B N 1 ATOM 5843 C CA . ASN B 1 286 ? 190.199 56.689 -64.034 1.00 27.08 ? 294 ASN B CA 1 ATOM 5844 C C . ASN B 1 286 ? 188.962 57.512 -63.728 1.00 25.69 ? 294 ASN B C 1 ATOM 5845 O O . ASN B 1 286 ? 188.089 57.073 -62.985 1.00 24.87 ? 294 ASN B O 1 ATOM 5846 C CB . ASN B 1 286 ? 191.345 57.095 -63.117 1.00 31.89 ? 294 ASN B CB 1 ATOM 5847 C CG . ASN B 1 286 ? 192.414 56.021 -63.030 1.00 37.84 ? 294 ASN B CG 1 ATOM 5848 O OD1 . ASN B 1 286 ? 192.169 54.933 -62.505 1.00 41.96 ? 294 ASN B OD1 1 ATOM 5849 N ND2 . ASN B 1 286 ? 193.604 56.314 -63.555 1.00 39.82 ? 294 ASN B ND2 1 ATOM 5850 N N . HIS B 1 287 ? 188.869 58.699 -64.310 1.00 25.00 ? 295 HIS B N 1 ATOM 5851 C CA . HIS B 1 287 ? 187.701 59.534 -64.061 1.00 25.18 ? 295 HIS B CA 1 ATOM 5852 C C . HIS B 1 287 ? 186.426 58.891 -64.633 1.00 24.11 ? 295 HIS B C 1 ATOM 5853 O O . HIS B 1 287 ? 186.320 58.663 -65.840 1.00 25.21 ? 295 HIS B O 1 ATOM 5854 C CB . HIS B 1 287 ? 187.891 60.925 -64.667 1.00 24.35 ? 295 HIS B CB 1 ATOM 5855 C CG . HIS B 1 287 ? 186.996 61.959 -64.064 1.00 26.63 ? 295 HIS B CG 1 ATOM 5856 N ND1 . HIS B 1 287 ? 186.625 63.110 -64.727 1.00 29.36 ? 295 HIS B ND1 1 ATOM 5857 C CD2 . HIS B 1 287 ? 186.380 62.004 -62.858 1.00 26.61 ? 295 HIS B CD2 1 ATOM 5858 C CE1 . HIS B 1 287 ? 185.817 63.818 -63.957 1.00 28.24 ? 295 HIS B CE1 1 ATOM 5859 N NE2 . HIS B 1 287 ? 185.652 63.169 -62.817 1.00 27.53 ? 295 HIS B NE2 1 ATOM 5860 N N . HIS B 1 288 ? 185.469 58.596 -63.756 1.00 22.17 ? 296 HIS B N 1 ATOM 5861 C CA . HIS B 1 288 ? 184.196 57.990 -64.145 1.00 20.18 ? 296 HIS B CA 1 ATOM 5862 C C . HIS B 1 288 ? 184.354 56.556 -64.616 1.00 20.28 ? 296 HIS B C 1 ATOM 5863 O O . HIS B 1 288 ? 183.567 56.078 -65.431 1.00 21.79 ? 296 HIS B O 1 ATOM 5864 C CB . HIS B 1 288 ? 183.510 58.793 -65.254 1.00 18.33 ? 296 HIS B CB 1 ATOM 5865 C CG . HIS B 1 288 ? 183.309 60.238 -64.925 1.00 17.25 ? 296 HIS B CG 1 ATOM 5866 N ND1 . HIS B 1 288 ? 182.729 60.664 -63.748 1.00 17.17 ? 296 HIS B ND1 1 ATOM 5867 C CD2 . HIS B 1 288 ? 183.586 61.358 -65.633 1.00 16.98 ? 296 HIS B CD2 1 ATOM 5868 C CE1 . HIS B 1 288 ? 182.656 61.982 -63.748 1.00 17.58 ? 296 HIS B CE1 1 ATOM 5869 N NE2 . HIS B 1 288 ? 183.168 62.428 -64.881 1.00 17.04 ? 296 HIS B NE2 1 ATOM 5870 N N . PHE B 1 289 ? 185.368 55.870 -64.107 1.00 19.45 ? 297 PHE B N 1 ATOM 5871 C CA . PHE B 1 289 ? 185.603 54.484 -64.474 1.00 19.21 ? 297 PHE B CA 1 ATOM 5872 C C . PHE B 1 289 ? 184.418 53.622 -64.017 1.00 20.62 ? 297 PHE B C 1 ATOM 5873 O O . PHE B 1 289 ? 183.934 53.747 -62.889 1.00 19.96 ? 297 PHE B O 1 ATOM 5874 C CB . PHE B 1 289 ? 186.896 53.999 -63.816 1.00 19.39 ? 297 PHE B CB 1 ATOM 5875 C CG . PHE B 1 289 ? 187.268 52.581 -64.158 1.00 19.22 ? 297 PHE B CG 1 ATOM 5876 C CD1 . PHE B 1 289 ? 187.520 52.207 -65.471 1.00 21.62 ? 297 PHE B CD1 1 ATOM 5877 C CD2 . PHE B 1 289 ? 187.395 51.627 -63.164 1.00 18.57 ? 297 PHE B CD2 1 ATOM 5878 C CE1 . PHE B 1 289 ? 187.896 50.897 -65.786 1.00 21.80 ? 297 PHE B CE1 1 ATOM 5879 C CE2 . PHE B 1 289 ? 187.768 50.321 -63.468 1.00 19.29 ? 297 PHE B CE2 1 ATOM 5880 C CZ . PHE B 1 289 ? 188.019 49.954 -64.781 1.00 19.25 ? 297 PHE B CZ 1 ATOM 5881 N N . MET B 1 290 ? 183.952 52.756 -64.909 1.00 20.60 ? 298 MET B N 1 ATOM 5882 C CA . MET B 1 290 ? 182.838 51.854 -64.628 1.00 20.88 ? 298 MET B CA 1 ATOM 5883 C C . MET B 1 290 ? 181.476 52.498 -64.365 1.00 20.49 ? 298 MET B C 1 ATOM 5884 O O . MET B 1 290 ? 180.518 51.800 -64.032 1.00 21.68 ? 298 MET B O 1 ATOM 5885 C CB . MET B 1 290 ? 183.194 50.908 -63.474 1.00 19.69 ? 298 MET B CB 1 ATOM 5886 C CG . MET B 1 290 ? 184.349 49.965 -63.805 1.00 22.22 ? 298 MET B CG 1 ATOM 5887 S SD . MET B 1 290 ? 184.338 48.440 -62.823 1.00 25.87 ? 298 MET B SD 1 ATOM 5888 C CE . MET B 1 290 ? 185.234 48.976 -61.365 1.00 30.73 ? 298 MET B CE 1 ATOM 5889 N N . GLU B 1 291 ? 181.376 53.813 -64.530 1.00 18.92 ? 299 GLU B N 1 ATOM 5890 C CA . GLU B 1 291 ? 180.104 54.486 -64.316 1.00 18.29 ? 299 GLU B CA 1 ATOM 5891 C C . GLU B 1 291 ? 179.062 53.969 -65.292 1.00 18.55 ? 299 GLU B C 1 ATOM 5892 O O . GLU B 1 291 ? 177.874 53.897 -64.969 1.00 18.10 ? 299 GLU B O 1 ATOM 5893 C CB . GLU B 1 291 ? 180.259 55.996 -64.488 1.00 17.96 ? 299 GLU B CB 1 ATOM 5894 C CG . GLU B 1 291 ? 180.350 56.742 -63.170 1.00 20.36 ? 299 GLU B CG 1 ATOM 5895 C CD . GLU B 1 291 ? 180.666 58.216 -63.338 1.00 21.41 ? 299 GLU B CD 1 ATOM 5896 O OE1 . GLU B 1 291 ? 179.940 58.911 -64.083 1.00 22.93 ? 299 GLU B OE1 1 ATOM 5897 O OE2 . GLU B 1 291 ? 181.643 58.680 -62.712 1.00 21.47 ? 299 GLU B OE2 1 ATOM 5898 N N . GLY B 1 292 ? 179.513 53.602 -66.487 1.00 18.79 ? 300 GLY B N 1 ATOM 5899 C CA . GLY B 1 292 ? 178.598 53.111 -67.502 1.00 18.17 ? 300 GLY B CA 1 ATOM 5900 C C . GLY B 1 292 ? 178.214 51.647 -67.396 1.00 18.35 ? 300 GLY B C 1 ATOM 5901 O O . GLY B 1 292 ? 177.491 51.145 -68.252 1.00 16.85 ? 300 GLY B O 1 ATOM 5902 N N . GLU B 1 293 ? 178.678 50.955 -66.358 1.00 19.58 ? 301 GLU B N 1 ATOM 5903 C CA . GLU B 1 293 ? 178.349 49.542 -66.205 1.00 20.02 ? 301 GLU B CA 1 ATOM 5904 C C . GLU B 1 293 ? 176.843 49.280 -66.129 1.00 21.11 ? 301 GLU B C 1 ATOM 5905 O O . GLU B 1 293 ? 176.336 48.373 -66.792 1.00 22.50 ? 301 GLU B O 1 ATOM 5906 C CB . GLU B 1 293 ? 179.057 48.965 -64.976 1.00 19.50 ? 301 GLU B CB 1 ATOM 5907 C CG . GLU B 1 293 ? 180.555 48.780 -65.179 1.00 20.52 ? 301 GLU B CG 1 ATOM 5908 C CD . GLU B 1 293 ? 180.879 47.743 -66.247 1.00 19.50 ? 301 GLU B CD 1 ATOM 5909 O OE1 . GLU B 1 293 ? 180.776 46.528 -65.965 1.00 19.67 ? 301 GLU B OE1 1 ATOM 5910 O OE2 . GLU B 1 293 ? 181.233 48.146 -67.373 1.00 18.45 ? 301 GLU B OE2 1 ATOM 5911 N N . ALA B 1 294 ? 176.127 50.078 -65.339 1.00 21.33 ? 302 ALA B N 1 ATOM 5912 C CA . ALA B 1 294 ? 174.683 49.905 -65.194 1.00 19.83 ? 302 ALA B CA 1 ATOM 5913 C C . ALA B 1 294 ? 173.966 49.849 -66.543 1.00 19.94 ? 302 ALA B C 1 ATOM 5914 O O . ALA B 1 294 ? 173.209 48.914 -66.804 1.00 20.08 ? 302 ALA B O 1 ATOM 5915 C CB . ALA B 1 294 ? 174.096 51.024 -64.331 1.00 18.78 ? 302 ALA B CB 1 ATOM 5916 N N . MET B 1 295 ? 174.195 50.831 -67.410 1.00 18.72 ? 303 MET B N 1 ATOM 5917 C CA . MET B 1 295 ? 173.521 50.812 -68.702 1.00 18.99 ? 303 MET B CA 1 ATOM 5918 C C . MET B 1 295 ? 174.078 49.711 -69.593 1.00 18.75 ? 303 MET B C 1 ATOM 5919 O O . MET B 1 295 ? 173.335 49.105 -70.361 1.00 18.99 ? 303 MET B O 1 ATOM 5920 C CB . MET B 1 295 ? 173.641 52.161 -69.415 1.00 18.06 ? 303 MET B CB 1 ATOM 5921 C CG . MET B 1 295 ? 172.794 52.239 -70.682 1.00 19.67 ? 303 MET B CG 1 ATOM 5922 S SD . MET B 1 295 ? 172.826 53.846 -71.529 1.00 22.63 ? 303 MET B SD 1 ATOM 5923 C CE . MET B 1 295 ? 171.606 54.736 -70.604 1.00 17.00 ? 303 MET B CE 1 ATOM 5924 N N . ARG B 1 296 ? 175.380 49.449 -69.497 1.00 18.33 ? 304 ARG B N 1 ATOM 5925 C CA . ARG B 1 296 ? 175.995 48.401 -70.311 1.00 18.19 ? 304 ARG B CA 1 ATOM 5926 C C . ARG B 1 296 ? 175.303 47.044 -70.100 1.00 18.68 ? 304 ARG B C 1 ATOM 5927 O O . ARG B 1 296 ? 174.943 46.380 -71.071 1.00 18.01 ? 304 ARG B O 1 ATOM 5928 C CB . ARG B 1 296 ? 177.495 48.269 -69.998 1.00 17.94 ? 304 ARG B CB 1 ATOM 5929 C CG . ARG B 1 296 ? 178.252 47.299 -70.931 1.00 18.43 ? 304 ARG B CG 1 ATOM 5930 C CD . ARG B 1 296 ? 179.723 47.106 -70.513 1.00 17.49 ? 304 ARG B CD 1 ATOM 5931 N NE . ARG B 1 296 ? 179.860 46.456 -69.207 1.00 19.30 ? 304 ARG B NE 1 ATOM 5932 C CZ . ARG B 1 296 ? 179.729 45.146 -68.988 1.00 19.77 ? 304 ARG B CZ 1 ATOM 5933 N NH1 . ARG B 1 296 ? 179.458 44.318 -69.989 1.00 19.05 ? 304 ARG B NH1 1 ATOM 5934 N NH2 . ARG B 1 296 ? 179.874 44.661 -67.761 1.00 17.63 ? 304 ARG B NH2 1 ATOM 5935 N N . THR B 1 297 ? 175.099 46.643 -68.842 1.00 18.48 ? 305 THR B N 1 ATOM 5936 C CA . THR B 1 297 ? 174.464 45.356 -68.551 1.00 18.18 ? 305 THR B CA 1 ATOM 5937 C C . THR B 1 297 ? 173.061 45.301 -69.095 1.00 18.19 ? 305 THR B C 1 ATOM 5938 O O . THR B 1 297 ? 172.482 44.231 -69.198 1.00 20.11 ? 305 THR B O 1 ATOM 5939 C CB . THR B 1 297 ? 174.340 45.057 -67.037 1.00 17.86 ? 305 THR B CB 1 ATOM 5940 O OG1 . THR B 1 297 ? 173.427 45.988 -66.442 1.00 18.47 ? 305 THR B OG1 1 ATOM 5941 C CG2 . THR B 1 297 ? 175.686 45.161 -66.348 1.00 18.33 ? 305 THR B CG2 1 ATOM 5942 N N . LYS B 1 298 ? 172.499 46.445 -69.441 1.00 18.35 ? 306 LYS B N 1 ATOM 5943 C CA . LYS B 1 298 ? 171.142 46.440 -69.955 1.00 18.81 ? 306 LYS B CA 1 ATOM 5944 C C . LYS B 1 298 ? 171.004 46.502 -71.474 1.00 19.07 ? 306 LYS B C 1 ATOM 5945 O O . LYS B 1 298 ? 170.190 45.778 -72.061 1.00 19.60 ? 306 LYS B O 1 ATOM 5946 C CB . LYS B 1 298 ? 170.346 47.573 -69.315 1.00 19.32 ? 306 LYS B CB 1 ATOM 5947 C CG . LYS B 1 298 ? 169.084 47.069 -68.656 1.00 22.18 ? 306 LYS B CG 1 ATOM 5948 C CD . LYS B 1 298 ? 168.862 47.697 -67.307 1.00 21.98 ? 306 LYS B CD 1 ATOM 5949 C CE . LYS B 1 298 ? 167.724 46.996 -66.580 1.00 24.81 ? 306 LYS B CE 1 ATOM 5950 N NZ . LYS B 1 298 ? 168.031 45.569 -66.297 1.00 23.14 ? 306 LYS B NZ 1 ATOM 5951 N N . PHE B 1 299 ? 171.806 47.336 -72.124 1.00 18.05 ? 307 PHE B N 1 ATOM 5952 C CA . PHE B 1 299 ? 171.683 47.467 -73.568 1.00 18.04 ? 307 PHE B CA 1 ATOM 5953 C C . PHE B 1 299 ? 172.787 46.883 -74.458 1.00 17.32 ? 307 PHE B C 1 ATOM 5954 O O . PHE B 1 299 ? 172.590 46.741 -75.667 1.00 16.11 ? 307 PHE B O 1 ATOM 5955 C CB . PHE B 1 299 ? 171.489 48.943 -73.924 1.00 18.66 ? 307 PHE B CB 1 ATOM 5956 C CG . PHE B 1 299 ? 170.308 49.582 -73.251 1.00 18.46 ? 307 PHE B CG 1 ATOM 5957 C CD1 . PHE B 1 299 ? 169.150 48.850 -72.995 1.00 18.41 ? 307 PHE B CD1 1 ATOM 5958 C CD2 . PHE B 1 299 ? 170.330 50.935 -72.929 1.00 17.54 ? 307 PHE B CD2 1 ATOM 5959 C CE1 . PHE B 1 299 ? 168.031 49.464 -72.424 1.00 18.93 ? 307 PHE B CE1 1 ATOM 5960 C CE2 . PHE B 1 299 ? 169.225 51.550 -72.365 1.00 17.35 ? 307 PHE B CE2 1 ATOM 5961 C CZ . PHE B 1 299 ? 168.071 50.814 -72.113 1.00 17.62 ? 307 PHE B CZ 1 ATOM 5962 N N . GLU B 1 300 ? 173.935 46.533 -73.887 1.00 18.15 ? 308 GLU B N 1 ATOM 5963 C CA . GLU B 1 300 ? 175.016 46.016 -74.718 1.00 18.77 ? 308 GLU B CA 1 ATOM 5964 C C . GLU B 1 300 ? 174.587 44.883 -75.641 1.00 19.08 ? 308 GLU B C 1 ATOM 5965 O O . GLU B 1 300 ? 174.857 44.922 -76.844 1.00 19.75 ? 308 GLU B O 1 ATOM 5966 C CB . GLU B 1 300 ? 176.199 45.562 -73.868 1.00 17.17 ? 308 GLU B CB 1 ATOM 5967 C CG . GLU B 1 300 ? 177.317 44.984 -74.715 1.00 17.78 ? 308 GLU B CG 1 ATOM 5968 C CD . GLU B 1 300 ? 178.586 44.761 -73.932 1.00 19.10 ? 308 GLU B CD 1 ATOM 5969 O OE1 . GLU B 1 300 ? 178.490 44.527 -72.705 1.00 21.19 ? 308 GLU B OE1 1 ATOM 5970 O OE2 . GLU B 1 300 ? 179.673 44.813 -74.540 1.00 17.00 ? 308 GLU B OE2 1 ATOM 5971 N N . ALA B 1 301 ? 173.917 43.877 -75.088 1.00 19.56 ? 309 ALA B N 1 ATOM 5972 C CA . ALA B 1 301 ? 173.482 42.743 -75.892 1.00 19.48 ? 309 ALA B CA 1 ATOM 5973 C C . ALA B 1 301 ? 172.659 43.219 -77.084 1.00 19.58 ? 309 ALA B C 1 ATOM 5974 O O . ALA B 1 301 ? 172.792 42.680 -78.183 1.00 20.79 ? 309 ALA B O 1 ATOM 5975 C CB . ALA B 1 301 ? 172.676 41.768 -75.040 1.00 18.27 ? 309 ALA B CB 1 ATOM 5976 N N . TRP B 1 302 ? 171.821 44.231 -76.880 1.00 18.35 ? 310 TRP B N 1 ATOM 5977 C CA . TRP B 1 302 ? 171.004 44.734 -77.977 1.00 18.80 ? 310 TRP B CA 1 ATOM 5978 C C . TRP B 1 302 ? 171.870 45.376 -79.050 1.00 19.25 ? 310 TRP B C 1 ATOM 5979 O O . TRP B 1 302 ? 171.646 45.149 -80.233 1.00 18.56 ? 310 TRP B O 1 ATOM 5980 C CB . TRP B 1 302 ? 169.966 45.752 -77.483 1.00 19.73 ? 310 TRP B CB 1 ATOM 5981 C CG . TRP B 1 302 ? 168.956 45.191 -76.510 1.00 21.14 ? 310 TRP B CG 1 ATOM 5982 C CD1 . TRP B 1 302 ? 168.911 43.920 -76.019 1.00 21.19 ? 310 TRP B CD1 1 ATOM 5983 C CD2 . TRP B 1 302 ? 167.886 45.905 -75.871 1.00 21.25 ? 310 TRP B CD2 1 ATOM 5984 N NE1 . TRP B 1 302 ? 167.888 43.796 -75.110 1.00 23.11 ? 310 TRP B NE1 1 ATOM 5985 C CE2 . TRP B 1 302 ? 167.243 44.999 -74.998 1.00 22.11 ? 310 TRP B CE2 1 ATOM 5986 C CE3 . TRP B 1 302 ? 167.415 47.220 -75.947 1.00 20.42 ? 310 TRP B CE3 1 ATOM 5987 C CZ2 . TRP B 1 302 ? 166.152 45.364 -74.204 1.00 23.11 ? 310 TRP B CZ2 1 ATOM 5988 C CZ3 . TRP B 1 302 ? 166.325 47.586 -75.153 1.00 23.71 ? 310 TRP B CZ3 1 ATOM 5989 C CH2 . TRP B 1 302 ? 165.709 46.660 -74.294 1.00 22.85 ? 310 TRP B CH2 1 ATOM 5990 N N . PHE B 1 303 ? 172.860 46.172 -78.652 1.00 18.94 ? 311 PHE B N 1 ATOM 5991 C CA . PHE B 1 303 ? 173.722 46.818 -79.635 1.00 19.00 ? 311 PHE B CA 1 ATOM 5992 C C . PHE B 1 303 ? 174.407 45.789 -80.518 1.00 20.60 ? 311 PHE B C 1 ATOM 5993 O O . PHE B 1 303 ? 174.624 46.034 -81.709 1.00 21.41 ? 311 PHE B O 1 ATOM 5994 C CB . PHE B 1 303 ? 174.784 47.694 -78.964 1.00 18.24 ? 311 PHE B CB 1 ATOM 5995 C CG . PHE B 1 303 ? 174.225 48.861 -78.194 1.00 17.74 ? 311 PHE B CG 1 ATOM 5996 C CD1 . PHE B 1 303 ? 172.943 49.333 -78.442 1.00 16.45 ? 311 PHE B CD1 1 ATOM 5997 C CD2 . PHE B 1 303 ? 175.002 49.512 -77.240 1.00 17.76 ? 311 PHE B CD2 1 ATOM 5998 C CE1 . PHE B 1 303 ? 172.439 50.441 -77.751 1.00 17.24 ? 311 PHE B CE1 1 ATOM 5999 C CE2 . PHE B 1 303 ? 174.509 50.618 -76.546 1.00 18.31 ? 311 PHE B CE2 1 ATOM 6000 C CZ . PHE B 1 303 ? 173.221 51.082 -76.805 1.00 16.90 ? 311 PHE B CZ 1 ATOM 6001 N N . VAL B 1 304 ? 174.748 44.639 -79.939 1.00 21.45 ? 312 VAL B N 1 ATOM 6002 C CA . VAL B 1 304 ? 175.399 43.577 -80.705 1.00 22.53 ? 312 VAL B CA 1 ATOM 6003 C C . VAL B 1 304 ? 174.399 42.861 -81.614 1.00 23.92 ? 312 VAL B C 1 ATOM 6004 O O . VAL B 1 304 ? 174.670 42.638 -82.795 1.00 24.76 ? 312 VAL B O 1 ATOM 6005 C CB . VAL B 1 304 ? 176.051 42.538 -79.772 1.00 22.17 ? 312 VAL B CB 1 ATOM 6006 C CG1 . VAL B 1 304 ? 176.506 41.324 -80.567 1.00 20.03 ? 312 VAL B CG1 1 ATOM 6007 C CG2 . VAL B 1 304 ? 177.229 43.163 -79.048 1.00 22.54 ? 312 VAL B CG2 1 ATOM 6008 N N . LYS B 1 305 ? 173.244 42.514 -81.055 1.00 23.83 ? 313 LYS B N 1 ATOM 6009 C CA . LYS B 1 305 ? 172.198 41.819 -81.795 1.00 24.10 ? 313 LYS B CA 1 ATOM 6010 C C . LYS B 1 305 ? 171.807 42.562 -83.068 1.00 24.31 ? 313 LYS B C 1 ATOM 6011 O O . LYS B 1 305 ? 171.613 41.947 -84.121 1.00 25.24 ? 313 LYS B O 1 ATOM 6012 C CB . LYS B 1 305 ? 170.968 41.639 -80.907 1.00 24.64 ? 313 LYS B CB 1 ATOM 6013 C CG . LYS B 1 305 ? 169.820 40.925 -81.581 1.00 28.51 ? 313 LYS B CG 1 ATOM 6014 C CD . LYS B 1 305 ? 168.605 40.893 -80.669 1.00 34.02 ? 313 LYS B CD 1 ATOM 6015 C CE . LYS B 1 305 ? 167.369 40.393 -81.408 1.00 36.94 ? 313 LYS B CE 1 ATOM 6016 N NZ . LYS B 1 305 ? 166.118 40.589 -80.605 1.00 40.11 ? 313 LYS B NZ 1 ATOM 6017 N N . TYR B 1 306 ? 171.697 43.884 -82.969 1.00 22.42 ? 314 TYR B N 1 ATOM 6018 C CA . TYR B 1 306 ? 171.319 44.709 -84.109 1.00 20.96 ? 314 TYR B CA 1 ATOM 6019 C C . TYR B 1 306 ? 172.520 45.279 -84.847 1.00 22.02 ? 314 TYR B C 1 ATOM 6020 O O . TYR B 1 306 ? 172.388 46.091 -85.776 1.00 21.47 ? 314 TYR B O 1 ATOM 6021 C CB . TYR B 1 306 ? 170.396 45.820 -83.641 1.00 20.33 ? 314 TYR B CB 1 ATOM 6022 C CG . TYR B 1 306 ? 169.041 45.290 -83.263 1.00 20.66 ? 314 TYR B CG 1 ATOM 6023 C CD1 . TYR B 1 306 ? 168.097 44.975 -84.244 1.00 19.83 ? 314 TYR B CD1 1 ATOM 6024 C CD2 . TYR B 1 306 ? 168.719 45.042 -81.932 1.00 20.28 ? 314 TYR B CD2 1 ATOM 6025 C CE1 . TYR B 1 306 ? 166.866 44.422 -83.905 1.00 20.58 ? 314 TYR B CE1 1 ATOM 6026 C CE2 . TYR B 1 306 ? 167.493 44.488 -81.580 1.00 20.90 ? 314 TYR B CE2 1 ATOM 6027 C CZ . TYR B 1 306 ? 166.569 44.181 -82.570 1.00 21.49 ? 314 TYR B CZ 1 ATOM 6028 O OH . TYR B 1 306 ? 165.348 43.636 -82.227 1.00 21.66 ? 314 TYR B OH 1 ATOM 6029 N N . LYS B 1 307 ? 173.697 44.846 -84.420 1.00 22.30 ? 315 LYS B N 1 ATOM 6030 C CA . LYS B 1 307 ? 174.942 45.265 -85.047 1.00 23.64 ? 315 LYS B CA 1 ATOM 6031 C C . LYS B 1 307 ? 175.086 46.772 -85.232 1.00 21.92 ? 315 LYS B C 1 ATOM 6032 O O . LYS B 1 307 ? 175.338 47.212 -86.341 1.00 21.71 ? 315 LYS B O 1 ATOM 6033 C CB . LYS B 1 307 ? 175.076 44.582 -86.418 1.00 23.69 ? 315 LYS B CB 1 ATOM 6034 C CG . LYS B 1 307 ? 175.071 43.058 -86.362 1.00 26.53 ? 315 LYS B CG 1 ATOM 6035 C CD . LYS B 1 307 ? 175.078 42.455 -87.769 1.00 31.15 ? 315 LYS B CD 1 ATOM 6036 C CE . LYS B 1 307 ? 174.852 40.940 -87.743 1.00 31.92 ? 315 LYS B CE 1 ATOM 6037 N NZ . LYS B 1 307 ? 175.950 40.202 -87.060 1.00 33.78 ? 315 LYS B NZ 1 ATOM 6038 N N . VAL B 1 308 ? 174.959 47.574 -84.178 1.00 21.20 ? 316 VAL B N 1 ATOM 6039 C CA . VAL B 1 308 ? 175.104 49.013 -84.394 1.00 19.95 ? 316 VAL B CA 1 ATOM 6040 C C . VAL B 1 308 ? 176.561 49.285 -84.770 1.00 19.65 ? 316 VAL B C 1 ATOM 6041 O O . VAL B 1 308 ? 177.473 48.582 -84.337 1.00 18.87 ? 316 VAL B O 1 ATOM 6042 C CB . VAL B 1 308 ? 174.662 49.856 -83.154 1.00 17.71 ? 316 VAL B CB 1 ATOM 6043 C CG1 . VAL B 1 308 ? 173.547 49.137 -82.421 1.00 15.76 ? 316 VAL B CG1 1 ATOM 6044 C CG2 . VAL B 1 308 ? 175.823 50.149 -82.253 1.00 17.53 ? 316 VAL B CG2 1 ATOM 6045 N N . ASP B 1 309 ? 176.773 50.298 -85.595 1.00 19.58 ? 317 ASP B N 1 ATOM 6046 C CA . ASP B 1 309 ? 178.114 50.618 -86.061 1.00 20.50 ? 317 ASP B CA 1 ATOM 6047 C C . ASP B 1 309 ? 179.028 51.322 -85.062 1.00 20.89 ? 317 ASP B C 1 ATOM 6048 O O . ASP B 1 309 ? 180.103 50.823 -84.744 1.00 20.27 ? 317 ASP B O 1 ATOM 6049 C CB . ASP B 1 309 ? 178.010 51.437 -87.349 1.00 20.22 ? 317 ASP B CB 1 ATOM 6050 C CG . ASP B 1 309 ? 177.421 50.635 -88.494 1.00 21.07 ? 317 ASP B CG 1 ATOM 6051 O OD1 . ASP B 1 309 ? 178.098 49.690 -88.947 1.00 21.73 ? 317 ASP B OD1 1 ATOM 6052 O OD2 . ASP B 1 309 ? 176.286 50.932 -88.931 1.00 21.24 ? 317 ASP B OD2 1 ATOM 6053 N N . VAL B 1 310 ? 178.603 52.479 -84.571 1.00 20.76 ? 318 VAL B N 1 ATOM 6054 C CA . VAL B 1 310 ? 179.407 53.239 -83.629 1.00 20.12 ? 318 VAL B CA 1 ATOM 6055 C C . VAL B 1 310 ? 178.549 53.780 -82.503 1.00 19.32 ? 318 VAL B C 1 ATOM 6056 O O . VAL B 1 310 ? 177.376 54.090 -82.694 1.00 18.69 ? 318 VAL B O 1 ATOM 6057 C CB . VAL B 1 310 ? 180.057 54.459 -84.299 1.00 19.95 ? 318 VAL B CB 1 ATOM 6058 C CG1 . VAL B 1 310 ? 181.334 54.827 -83.571 1.00 21.95 ? 318 VAL B CG1 1 ATOM 6059 C CG2 . VAL B 1 310 ? 180.299 54.182 -85.751 1.00 23.09 ? 318 VAL B CG2 1 ATOM 6060 N N . VAL B 1 311 ? 179.155 53.900 -81.332 1.00 18.60 ? 319 VAL B N 1 ATOM 6061 C CA . VAL B 1 311 ? 178.488 54.443 -80.159 1.00 18.87 ? 319 VAL B CA 1 ATOM 6062 C C . VAL B 1 311 ? 179.376 55.599 -79.699 1.00 19.60 ? 319 VAL B C 1 ATOM 6063 O O . VAL B 1 311 ? 180.553 55.396 -79.375 1.00 20.51 ? 319 VAL B O 1 ATOM 6064 C CB . VAL B 1 311 ? 178.379 53.391 -79.023 1.00 19.29 ? 319 VAL B CB 1 ATOM 6065 C CG1 . VAL B 1 311 ? 177.868 54.046 -77.747 1.00 16.49 ? 319 VAL B CG1 1 ATOM 6066 C CG2 . VAL B 1 311 ? 177.448 52.261 -79.448 1.00 19.28 ? 319 VAL B CG2 1 ATOM 6067 N N . PHE B 1 312 ? 178.826 56.808 -79.700 1.00 18.27 ? 320 PHE B N 1 ATOM 6068 C CA . PHE B 1 312 ? 179.577 57.983 -79.279 1.00 17.62 ? 320 PHE B CA 1 ATOM 6069 C C . PHE B 1 312 ? 179.131 58.437 -77.880 1.00 16.69 ? 320 PHE B C 1 ATOM 6070 O O . PHE B 1 312 ? 177.934 58.448 -77.575 1.00 16.73 ? 320 PHE B O 1 ATOM 6071 C CB . PHE B 1 312 ? 179.360 59.126 -80.272 1.00 17.35 ? 320 PHE B CB 1 ATOM 6072 C CG . PHE B 1 312 ? 179.975 58.899 -81.630 1.00 16.27 ? 320 PHE B CG 1 ATOM 6073 C CD1 . PHE B 1 312 ? 181.353 58.951 -81.807 1.00 16.87 ? 320 PHE B CD1 1 ATOM 6074 C CD2 . PHE B 1 312 ? 179.166 58.684 -82.746 1.00 17.23 ? 320 PHE B CD2 1 ATOM 6075 C CE1 . PHE B 1 312 ? 181.916 58.801 -83.077 1.00 16.84 ? 320 PHE B CE1 1 ATOM 6076 C CE2 . PHE B 1 312 ? 179.718 58.533 -84.020 1.00 16.37 ? 320 PHE B CE2 1 ATOM 6077 C CZ . PHE B 1 312 ? 181.092 58.591 -84.187 1.00 16.39 ? 320 PHE B CZ 1 ATOM 6078 N N . ALA B 1 313 ? 180.096 58.815 -77.044 1.00 14.55 ? 321 ALA B N 1 ATOM 6079 C CA . ALA B 1 313 ? 179.818 59.285 -75.689 1.00 13.42 ? 321 ALA B CA 1 ATOM 6080 C C . ALA B 1 313 ? 180.812 60.376 -75.304 1.00 14.77 ? 321 ALA B C 1 ATOM 6081 O O . ALA B 1 313 ? 181.839 60.562 -75.966 1.00 14.94 ? 321 ALA B O 1 ATOM 6082 C CB . ALA B 1 313 ? 179.917 58.136 -74.710 1.00 12.13 ? 321 ALA B CB 1 ATOM 6083 N N . GLY B 1 314 ? 180.498 61.106 -74.239 1.00 14.12 ? 322 GLY B N 1 ATOM 6084 C CA . GLY B 1 314 ? 181.387 62.150 -73.771 1.00 13.69 ? 322 GLY B CA 1 ATOM 6085 C C . GLY B 1 314 ? 181.704 61.853 -72.320 1.00 14.36 ? 322 GLY B C 1 ATOM 6086 O O . GLY B 1 314 ? 182.263 60.792 -72.015 1.00 11.87 ? 322 GLY B O 1 ATOM 6087 N N . HIS B 1 315 ? 181.345 62.785 -71.434 1.00 14.76 ? 323 HIS B N 1 ATOM 6088 C CA . HIS B 1 315 ? 181.529 62.641 -69.989 1.00 15.34 ? 323 HIS B CA 1 ATOM 6089 C C . HIS B 1 315 ? 182.986 62.598 -69.506 1.00 16.75 ? 323 HIS B C 1 ATOM 6090 O O . HIS B 1 315 ? 183.351 63.343 -68.591 1.00 16.64 ? 323 HIS B O 1 ATOM 6091 C CB . HIS B 1 315 ? 180.757 61.412 -69.494 1.00 13.87 ? 323 HIS B CB 1 ATOM 6092 C CG . HIS B 1 315 ? 180.468 61.429 -68.026 1.00 16.39 ? 323 HIS B CG 1 ATOM 6093 N ND1 . HIS B 1 315 ? 179.987 62.549 -67.372 1.00 15.66 ? 323 HIS B ND1 1 ATOM 6094 C CD2 . HIS B 1 315 ? 180.545 60.457 -67.088 1.00 16.12 ? 323 HIS B CD2 1 ATOM 6095 C CE1 . HIS B 1 315 ? 179.781 62.262 -66.103 1.00 15.34 ? 323 HIS B CE1 1 ATOM 6096 N NE2 . HIS B 1 315 ? 180.111 60.996 -65.902 1.00 17.68 ? 323 HIS B NE2 1 ATOM 6097 N N . VAL B 1 316 ? 183.806 61.720 -70.082 1.00 15.70 ? 324 VAL B N 1 ATOM 6098 C CA . VAL B 1 316 ? 185.214 61.662 -69.710 1.00 15.44 ? 324 VAL B CA 1 ATOM 6099 C C . VAL B 1 316 ? 185.858 62.720 -70.592 1.00 17.51 ? 324 VAL B C 1 ATOM 6100 O O . VAL B 1 316 ? 185.747 62.677 -71.819 1.00 18.23 ? 324 VAL B O 1 ATOM 6101 C CB . VAL B 1 316 ? 185.838 60.279 -69.998 1.00 15.60 ? 324 VAL B CB 1 ATOM 6102 C CG1 . VAL B 1 316 ? 187.360 60.350 -69.873 1.00 13.87 ? 324 VAL B CG1 1 ATOM 6103 C CG2 . VAL B 1 316 ? 185.291 59.262 -69.010 1.00 13.16 ? 324 VAL B CG2 1 ATOM 6104 N N . HIS B 1 317 ? 186.516 63.684 -69.967 1.00 19.15 ? 325 HIS B N 1 ATOM 6105 C CA . HIS B 1 317 ? 187.123 64.778 -70.701 1.00 20.79 ? 325 HIS B CA 1 ATOM 6106 C C . HIS B 1 317 ? 188.434 64.377 -71.343 1.00 21.29 ? 325 HIS B C 1 ATOM 6107 O O . HIS B 1 317 ? 189.519 64.758 -70.897 1.00 21.81 ? 325 HIS B O 1 ATOM 6108 C CB . HIS B 1 317 ? 187.273 65.961 -69.750 1.00 21.47 ? 325 HIS B CB 1 ATOM 6109 C CG . HIS B 1 317 ? 185.967 66.405 -69.166 1.00 23.70 ? 325 HIS B CG 1 ATOM 6110 N ND1 . HIS B 1 317 ? 185.874 67.223 -68.062 1.00 25.46 ? 325 HIS B ND1 1 ATOM 6111 C CD2 . HIS B 1 317 ? 184.694 66.142 -69.547 1.00 23.37 ? 325 HIS B CD2 1 ATOM 6112 C CE1 . HIS B 1 317 ? 184.600 67.444 -67.786 1.00 25.25 ? 325 HIS B CE1 1 ATOM 6113 N NE2 . HIS B 1 317 ? 183.865 66.799 -68.673 1.00 24.60 ? 325 HIS B NE2 1 ATOM 6114 N N . ALA B 1 318 ? 188.312 63.594 -72.408 1.00 20.44 ? 326 ALA B N 1 ATOM 6115 C CA . ALA B 1 318 ? 189.466 63.096 -73.136 1.00 21.36 ? 326 ALA B CA 1 ATOM 6116 C C . ALA B 1 318 ? 189.001 62.347 -74.371 1.00 22.06 ? 326 ALA B C 1 ATOM 6117 O O . ALA B 1 318 ? 187.829 62.422 -74.761 1.00 21.16 ? 326 ALA B O 1 ATOM 6118 C CB . ALA B 1 318 ? 190.290 62.164 -72.243 1.00 20.46 ? 326 ALA B CB 1 ATOM 6119 N N . TYR B 1 319 ? 189.928 61.616 -74.980 1.00 22.36 ? 327 TYR B N 1 ATOM 6120 C CA . TYR B 1 319 ? 189.624 60.851 -76.181 1.00 21.61 ? 327 TYR B CA 1 ATOM 6121 C C . TYR B 1 319 ? 190.022 59.389 -76.026 1.00 20.98 ? 327 TYR B C 1 ATOM 6122 O O . TYR B 1 319 ? 191.055 59.067 -75.436 1.00 20.91 ? 327 TYR B O 1 ATOM 6123 C CB . TYR B 1 319 ? 190.352 61.445 -77.393 1.00 20.76 ? 327 TYR B CB 1 ATOM 6124 C CG . TYR B 1 319 ? 190.090 60.695 -78.680 1.00 21.75 ? 327 TYR B CG 1 ATOM 6125 C CD1 . TYR B 1 319 ? 188.822 60.687 -79.265 1.00 21.23 ? 327 TYR B CD1 1 ATOM 6126 C CD2 . TYR B 1 319 ? 191.102 59.962 -79.297 1.00 21.56 ? 327 TYR B CD2 1 ATOM 6127 C CE1 . TYR B 1 319 ? 188.571 59.967 -80.433 1.00 21.14 ? 327 TYR B CE1 1 ATOM 6128 C CE2 . TYR B 1 319 ? 190.861 59.234 -80.468 1.00 19.56 ? 327 TYR B CE2 1 ATOM 6129 C CZ . TYR B 1 319 ? 189.597 59.242 -81.027 1.00 21.14 ? 327 TYR B CZ 1 ATOM 6130 O OH . TYR B 1 319 ? 189.364 58.525 -82.182 1.00 21.47 ? 327 TYR B OH 1 ATOM 6131 N N . GLU B 1 320 ? 189.179 58.507 -76.547 1.00 20.72 ? 328 GLU B N 1 ATOM 6132 C CA . GLU B 1 320 ? 189.446 57.080 -76.507 1.00 19.98 ? 328 GLU B CA 1 ATOM 6133 C C . GLU B 1 320 ? 188.629 56.365 -77.578 1.00 19.82 ? 328 GLU B C 1 ATOM 6134 O O . GLU B 1 320 ? 187.490 56.737 -77.863 1.00 19.54 ? 328 GLU B O 1 ATOM 6135 C CB . GLU B 1 320 ? 189.142 56.501 -75.127 1.00 18.15 ? 328 GLU B CB 1 ATOM 6136 C CG . GLU B 1 320 ? 189.360 54.999 -75.077 1.00 18.27 ? 328 GLU B CG 1 ATOM 6137 C CD . GLU B 1 320 ? 189.364 54.433 -73.673 1.00 17.90 ? 328 GLU B CD 1 ATOM 6138 O OE1 . GLU B 1 320 ? 188.659 54.981 -72.798 1.00 16.51 ? 328 GLU B OE1 1 ATOM 6139 O OE2 . GLU B 1 320 ? 190.067 53.422 -73.455 1.00 17.76 ? 328 GLU B OE2 1 ATOM 6140 N N . ARG B 1 321 ? 189.231 55.340 -78.172 1.00 20.41 ? 329 ARG B N 1 ATOM 6141 C CA . ARG B 1 321 ? 188.608 54.549 -79.235 1.00 21.25 ? 329 ARG B CA 1 ATOM 6142 C C . ARG B 1 321 ? 188.822 53.079 -78.896 1.00 20.81 ? 329 ARG B C 1 ATOM 6143 O O . ARG B 1 321 ? 189.954 52.653 -78.677 1.00 20.89 ? 329 ARG B O 1 ATOM 6144 C CB . ARG B 1 321 ? 189.281 54.862 -80.584 1.00 21.89 ? 329 ARG B CB 1 ATOM 6145 C CG . ARG B 1 321 ? 188.606 54.258 -81.805 1.00 22.53 ? 329 ARG B CG 1 ATOM 6146 C CD . ARG B 1 321 ? 189.415 54.537 -83.070 1.00 22.98 ? 329 ARG B CD 1 ATOM 6147 N NE . ARG B 1 321 ? 190.338 53.448 -83.376 1.00 24.91 ? 329 ARG B NE 1 ATOM 6148 C CZ . ARG B 1 321 ? 191.611 53.621 -83.713 1.00 24.49 ? 329 ARG B CZ 1 ATOM 6149 N NH1 . ARG B 1 321 ? 192.119 54.845 -83.786 1.00 23.36 ? 329 ARG B NH1 1 ATOM 6150 N NH2 . ARG B 1 321 ? 192.377 52.570 -83.969 1.00 26.27 ? 329 ARG B NH2 1 ATOM 6151 N N . SER B 1 322 ? 187.747 52.301 -78.861 1.00 20.15 ? 330 SER B N 1 ATOM 6152 C CA . SER B 1 322 ? 187.870 50.886 -78.537 1.00 19.62 ? 330 SER B CA 1 ATOM 6153 C C . SER B 1 322 ? 187.925 49.994 -79.768 1.00 20.43 ? 330 SER B C 1 ATOM 6154 O O . SER B 1 322 ? 187.652 50.428 -80.888 1.00 18.77 ? 330 SER B O 1 ATOM 6155 C CB . SER B 1 322 ? 186.684 50.434 -77.682 1.00 18.49 ? 330 SER B CB 1 ATOM 6156 O OG . SER B 1 322 ? 185.507 50.317 -78.467 1.00 16.34 ? 330 SER B OG 1 ATOM 6157 N N . GLU B 1 323 ? 188.297 48.741 -79.538 1.00 21.32 ? 331 GLU B N 1 ATOM 6158 C CA . GLU B 1 323 ? 188.316 47.737 -80.587 1.00 23.94 ? 331 GLU B CA 1 ATOM 6159 C C . GLU B 1 323 ? 186.849 47.321 -80.562 1.00 23.59 ? 331 GLU B C 1 ATOM 6160 O O . GLU B 1 323 ? 186.118 47.712 -79.652 1.00 22.98 ? 331 GLU B O 1 ATOM 6161 C CB . GLU B 1 323 ? 189.151 46.519 -80.166 1.00 27.76 ? 331 GLU B CB 1 ATOM 6162 C CG . GLU B 1 323 ? 190.630 46.767 -79.857 1.00 32.73 ? 331 GLU B CG 1 ATOM 6163 C CD . GLU B 1 323 ? 191.474 47.004 -81.106 1.00 36.23 ? 331 GLU B CD 1 ATOM 6164 O OE1 . GLU B 1 323 ? 191.129 46.456 -82.179 1.00 37.10 ? 331 GLU B OE1 1 ATOM 6165 O OE2 . GLU B 1 323 ? 192.493 47.727 -81.007 1.00 37.93 ? 331 GLU B OE2 1 ATOM 6166 N N . ARG B 1 324 ? 186.401 46.548 -81.542 1.00 23.46 ? 332 ARG B N 1 ATOM 6167 C CA . ARG B 1 324 ? 185.023 46.089 -81.501 1.00 23.29 ? 332 ARG B CA 1 ATOM 6168 C C . ARG B 1 324 ? 185.063 44.965 -80.471 1.00 23.67 ? 332 ARG B C 1 ATOM 6169 O O . ARG B 1 324 ? 185.721 43.937 -80.674 1.00 23.68 ? 332 ARG B O 1 ATOM 6170 C CB . ARG B 1 324 ? 184.581 45.575 -82.866 1.00 22.87 ? 332 ARG B CB 1 ATOM 6171 C CG . ARG B 1 324 ? 184.398 46.685 -83.884 1.00 22.23 ? 332 ARG B CG 1 ATOM 6172 C CD . ARG B 1 324 ? 183.916 46.140 -85.212 1.00 21.94 ? 332 ARG B CD 1 ATOM 6173 N NE . ARG B 1 324 ? 183.741 47.198 -86.203 1.00 22.66 ? 332 ARG B NE 1 ATOM 6174 C CZ . ARG B 1 324 ? 182.757 48.093 -86.184 1.00 21.24 ? 332 ARG B CZ 1 ATOM 6175 N NH1 . ARG B 1 324 ? 181.848 48.063 -85.219 1.00 20.32 ? 332 ARG B NH1 1 ATOM 6176 N NH2 . ARG B 1 324 ? 182.681 49.015 -87.135 1.00 20.38 ? 332 ARG B NH2 1 ATOM 6177 N N . VAL B 1 325 ? 184.373 45.175 -79.356 1.00 23.37 ? 333 VAL B N 1 ATOM 6178 C CA . VAL B 1 325 ? 184.370 44.208 -78.267 1.00 23.51 ? 333 VAL B CA 1 ATOM 6179 C C . VAL B 1 325 ? 182.988 44.046 -77.643 1.00 22.52 ? 333 VAL B C 1 ATOM 6180 O O . VAL B 1 325 ? 182.113 44.894 -77.824 1.00 22.88 ? 333 VAL B O 1 ATOM 6181 C CB . VAL B 1 325 ? 185.357 44.670 -77.167 1.00 23.76 ? 333 VAL B CB 1 ATOM 6182 C CG1 . VAL B 1 325 ? 185.310 43.737 -75.984 1.00 26.44 ? 333 VAL B CG1 1 ATOM 6183 C CG2 . VAL B 1 325 ? 186.769 44.735 -77.732 1.00 24.82 ? 333 VAL B CG2 1 ATOM 6184 N N . SER B 1 326 ? 182.791 42.945 -76.927 1.00 21.18 ? 334 SER B N 1 ATOM 6185 C CA . SER B 1 326 ? 181.534 42.699 -76.231 1.00 21.84 ? 334 SER B CA 1 ATOM 6186 C C . SER B 1 326 ? 181.837 41.922 -74.953 1.00 22.35 ? 334 SER B C 1 ATOM 6187 O O . SER B 1 326 ? 182.846 41.207 -74.856 1.00 22.32 ? 334 SER B O 1 ATOM 6188 C CB . SER B 1 326 ? 180.549 41.919 -77.107 1.00 21.97 ? 334 SER B CB 1 ATOM 6189 O OG . SER B 1 326 ? 180.964 40.579 -77.273 1.00 22.11 ? 334 SER B OG 1 ATOM 6190 N N . ASN B 1 327 ? 180.965 42.075 -73.967 1.00 21.85 ? 335 ASN B N 1 ATOM 6191 C CA . ASN B 1 327 ? 181.141 41.410 -72.680 1.00 22.06 ? 335 ASN B CA 1 ATOM 6192 C C . ASN B 1 327 ? 179.745 40.955 -72.279 1.00 21.22 ? 335 ASN B C 1 ATOM 6193 O O . ASN B 1 327 ? 179.249 41.291 -71.211 1.00 20.94 ? 335 ASN B O 1 ATOM 6194 C CB . ASN B 1 327 ? 181.700 42.425 -71.675 1.00 22.05 ? 335 ASN B CB 1 ATOM 6195 C CG . ASN B 1 327 ? 182.181 41.789 -70.395 1.00 23.03 ? 335 ASN B CG 1 ATOM 6196 O OD1 . ASN B 1 327 ? 182.112 40.573 -70.220 1.00 23.59 ? 335 ASN B OD1 1 ATOM 6197 N ND2 . ASN B 1 327 ? 182.683 42.617 -69.484 1.00 23.45 ? 335 ASN B ND2 1 ATOM 6198 N N . ILE B 1 328 ? 179.121 40.176 -73.152 1.00 21.36 ? 336 ILE B N 1 ATOM 6199 C CA . ILE B 1 328 ? 177.761 39.727 -72.918 1.00 21.43 ? 336 ILE B CA 1 ATOM 6200 C C . ILE B 1 328 ? 177.583 38.246 -72.625 1.00 21.62 ? 336 ILE B C 1 ATOM 6201 O O . ILE B 1 328 ? 176.495 37.709 -72.821 1.00 23.17 ? 336 ILE B O 1 ATOM 6202 C CB . ILE B 1 328 ? 176.869 40.082 -74.124 1.00 21.50 ? 336 ILE B CB 1 ATOM 6203 C CG1 . ILE B 1 328 ? 177.385 39.381 -75.384 1.00 22.88 ? 336 ILE B CG1 1 ATOM 6204 C CG2 . ILE B 1 328 ? 176.877 41.588 -74.357 1.00 21.19 ? 336 ILE B CG2 1 ATOM 6205 C CD1 . ILE B 1 328 ? 176.438 39.535 -76.592 1.00 22.52 ? 336 ILE B CD1 1 ATOM 6206 N N . ALA B 1 329 ? 178.628 37.580 -72.155 1.00 19.90 ? 337 ALA B N 1 ATOM 6207 C CA . ALA B 1 329 ? 178.501 36.163 -71.854 1.00 19.35 ? 337 ALA B CA 1 ATOM 6208 C C . ALA B 1 329 ? 178.463 35.888 -70.351 1.00 20.20 ? 337 ALA B C 1 ATOM 6209 O O . ALA B 1 329 ? 178.286 34.745 -69.923 1.00 20.52 ? 337 ALA B O 1 ATOM 6210 C CB . ALA B 1 329 ? 179.639 35.408 -72.483 1.00 19.49 ? 337 ALA B CB 1 ATOM 6211 N N . TYR B 1 330 ? 178.620 36.936 -69.551 1.00 20.38 ? 338 TYR B N 1 ATOM 6212 C CA . TYR B 1 330 ? 178.632 36.797 -68.099 1.00 20.00 ? 338 TYR B CA 1 ATOM 6213 C C . TYR B 1 330 ? 177.334 36.257 -67.535 1.00 20.14 ? 338 TYR B C 1 ATOM 6214 O O . TYR B 1 330 ? 176.252 36.660 -67.953 1.00 19.44 ? 338 TYR B O 1 ATOM 6215 C CB . TYR B 1 330 ? 178.917 38.147 -67.453 1.00 19.97 ? 338 TYR B CB 1 ATOM 6216 C CG . TYR B 1 330 ? 178.971 38.125 -65.947 1.00 18.72 ? 338 TYR B CG 1 ATOM 6217 C CD1 . TYR B 1 330 ? 179.888 37.311 -65.276 1.00 19.38 ? 338 TYR B CD1 1 ATOM 6218 C CD2 . TYR B 1 330 ? 178.167 38.977 -65.192 1.00 18.86 ? 338 TYR B CD2 1 ATOM 6219 C CE1 . TYR B 1 330 ? 180.014 37.354 -63.886 1.00 19.36 ? 338 TYR B CE1 1 ATOM 6220 C CE2 . TYR B 1 330 ? 178.282 39.027 -63.797 1.00 20.41 ? 338 TYR B CE2 1 ATOM 6221 C CZ . TYR B 1 330 ? 179.214 38.217 -63.156 1.00 19.49 ? 338 TYR B CZ 1 ATOM 6222 O OH . TYR B 1 330 ? 179.380 38.311 -61.796 1.00 20.74 ? 338 TYR B OH 1 ATOM 6223 N N . LYS B 1 331 ? 177.444 35.353 -66.568 1.00 20.22 ? 339 LYS B N 1 ATOM 6224 C CA . LYS B 1 331 ? 176.263 34.792 -65.940 1.00 21.11 ? 339 LYS B CA 1 ATOM 6225 C C . LYS B 1 331 ? 176.426 34.632 -64.436 1.00 22.25 ? 339 LYS B C 1 ATOM 6226 O O . LYS B 1 331 ? 176.015 33.625 -63.852 1.00 22.74 ? 339 LYS B O 1 ATOM 6227 C CB . LYS B 1 331 ? 175.900 33.464 -66.587 1.00 21.21 ? 339 LYS B CB 1 ATOM 6228 C CG . LYS B 1 331 ? 175.364 33.641 -67.982 1.00 22.05 ? 339 LYS B CG 1 ATOM 6229 C CD . LYS B 1 331 ? 174.794 32.356 -68.524 1.00 27.76 ? 339 LYS B CD 1 ATOM 6230 C CE . LYS B 1 331 ? 174.351 32.555 -69.962 1.00 31.45 ? 339 LYS B CE 1 ATOM 6231 N NZ . LYS B 1 331 ? 173.512 33.791 -70.076 1.00 33.97 ? 339 LYS B NZ 1 ATOM 6232 N N . ILE B 1 332 ? 177.022 35.647 -63.817 1.00 21.64 ? 340 ILE B N 1 ATOM 6233 C CA . ILE B 1 332 ? 177.235 35.671 -62.376 1.00 21.43 ? 340 ILE B CA 1 ATOM 6234 C C . ILE B 1 332 ? 178.263 34.670 -61.850 1.00 21.95 ? 340 ILE B C 1 ATOM 6235 O O . ILE B 1 332 ? 179.160 35.045 -61.101 1.00 23.15 ? 340 ILE B O 1 ATOM 6236 C CB . ILE B 1 332 ? 175.915 35.431 -61.610 1.00 19.88 ? 340 ILE B CB 1 ATOM 6237 C CG1 . ILE B 1 332 ? 174.821 36.371 -62.125 1.00 20.54 ? 340 ILE B CG1 1 ATOM 6238 C CG2 . ILE B 1 332 ? 176.138 35.668 -60.130 1.00 18.69 ? 340 ILE B CG2 1 ATOM 6239 C CD1 . ILE B 1 332 ? 175.127 37.853 -61.938 1.00 22.56 ? 340 ILE B CD1 1 ATOM 6240 N N . THR B 1 333 ? 178.150 33.404 -62.230 1.00 22.12 ? 341 THR B N 1 ATOM 6241 C CA . THR B 1 333 ? 179.094 32.416 -61.714 1.00 24.78 ? 341 THR B CA 1 ATOM 6242 C C . THR B 1 333 ? 179.841 31.563 -62.747 1.00 25.24 ? 341 THR B C 1 ATOM 6243 O O . THR B 1 333 ? 180.509 30.592 -62.385 1.00 25.03 ? 341 THR B O 1 ATOM 6244 C CB . THR B 1 333 ? 178.386 31.470 -60.715 1.00 25.31 ? 341 THR B CB 1 ATOM 6245 O OG1 . THR B 1 333 ? 177.326 30.776 -61.380 1.00 26.16 ? 341 THR B OG1 1 ATOM 6246 C CG2 . THR B 1 333 ? 177.791 32.264 -59.557 1.00 25.22 ? 341 THR B CG2 1 ATOM 6247 N N . ASN B 1 334 ? 179.746 31.934 -64.020 1.00 25.62 ? 342 ASN B N 1 ATOM 6248 C CA . ASN B 1 334 ? 180.402 31.179 -65.079 1.00 26.44 ? 342 ASN B CA 1 ATOM 6249 C C . ASN B 1 334 ? 181.785 31.740 -65.394 1.00 26.00 ? 342 ASN B C 1 ATOM 6250 O O . ASN B 1 334 ? 182.470 31.248 -66.294 1.00 27.53 ? 342 ASN B O 1 ATOM 6251 C CB . ASN B 1 334 ? 179.533 31.186 -66.339 1.00 28.23 ? 342 ASN B CB 1 ATOM 6252 C CG . ASN B 1 334 ? 179.468 32.549 -66.993 1.00 31.22 ? 342 ASN B CG 1 ATOM 6253 O OD1 . ASN B 1 334 ? 179.634 33.562 -66.284 1.00 32.24 ? 342 ASN B OD1 1 ATOM 6254 N ND2 . ASN B 1 334 ? 179.236 32.608 -68.219 1.00 35.57 ? 342 ASN B ND2 1 ATOM 6255 N N . GLY B 1 335 ? 182.191 32.773 -64.661 1.00 23.77 ? 343 GLY B N 1 ATOM 6256 C CA . GLY B 1 335 ? 183.503 33.356 -64.873 1.00 21.77 ? 343 GLY B CA 1 ATOM 6257 C C . GLY B 1 335 ? 183.780 34.065 -66.190 1.00 21.86 ? 343 GLY B C 1 ATOM 6258 O O . GLY B 1 335 ? 184.853 34.647 -66.351 1.00 21.73 ? 343 GLY B O 1 ATOM 6259 N N . LEU B 1 336 ? 182.846 34.033 -67.136 1.00 20.75 ? 344 LEU B N 1 ATOM 6260 C CA . LEU B 1 336 ? 183.070 34.712 -68.410 1.00 21.18 ? 344 LEU B CA 1 ATOM 6261 C C . LEU B 1 336 ? 182.757 36.186 -68.255 1.00 21.76 ? 344 LEU B C 1 ATOM 6262 O O . LEU B 1 336 ? 181.634 36.617 -68.519 1.00 22.62 ? 344 LEU B O 1 ATOM 6263 C CB . LEU B 1 336 ? 182.182 34.122 -69.499 1.00 19.72 ? 344 LEU B CB 1 ATOM 6264 C CG . LEU B 1 336 ? 182.460 32.647 -69.762 1.00 21.51 ? 344 LEU B CG 1 ATOM 6265 C CD1 . LEU B 1 336 ? 181.527 32.127 -70.844 1.00 21.30 ? 344 LEU B CD1 1 ATOM 6266 C CD2 . LEU B 1 336 ? 183.917 32.480 -70.169 1.00 21.02 ? 344 LEU B CD2 1 ATOM 6267 N N . CYS B 1 337 ? 183.741 36.966 -67.827 1.00 21.37 ? 345 CYS B N 1 ATOM 6268 C CA . CYS B 1 337 ? 183.500 38.384 -67.637 1.00 21.23 ? 345 CYS B CA 1 ATOM 6269 C C . CYS B 1 337 ? 184.630 39.261 -68.138 1.00 22.01 ? 345 CYS B C 1 ATOM 6270 O O . CYS B 1 337 ? 184.863 40.351 -67.618 1.00 21.85 ? 345 CYS B O 1 ATOM 6271 C CB . CYS B 1 337 ? 183.242 38.673 -66.164 1.00 21.52 ? 345 CYS B CB 1 ATOM 6272 S SG . CYS B 1 337 ? 184.677 38.334 -65.095 1.00 24.83 ? 345 CYS B SG 1 ATOM 6273 N N . THR B 1 338 ? 185.345 38.772 -69.141 1.00 22.40 ? 346 THR B N 1 ATOM 6274 C CA . THR B 1 338 ? 186.425 39.536 -69.743 1.00 23.56 ? 346 THR B CA 1 ATOM 6275 C C . THR B 1 338 ? 185.936 39.904 -71.135 1.00 23.89 ? 346 THR B C 1 ATOM 6276 O O . THR B 1 338 ? 185.383 39.066 -71.844 1.00 23.84 ? 346 THR B O 1 ATOM 6277 C CB . THR B 1 338 ? 187.719 38.712 -69.870 1.00 23.42 ? 346 THR B CB 1 ATOM 6278 O OG1 . THR B 1 338 ? 188.169 38.330 -68.563 1.00 24.40 ? 346 THR B OG1 1 ATOM 6279 C CG2 . THR B 1 338 ? 188.808 39.537 -70.555 1.00 21.57 ? 346 THR B CG2 1 ATOM 6280 N N . PRO B 1 339 ? 186.107 41.171 -71.533 1.00 24.93 ? 347 PRO B N 1 ATOM 6281 C CA . PRO B 1 339 ? 185.673 41.639 -72.853 1.00 26.00 ? 347 PRO B CA 1 ATOM 6282 C C . PRO B 1 339 ? 186.397 40.864 -73.938 1.00 26.96 ? 347 PRO B C 1 ATOM 6283 O O . PRO B 1 339 ? 187.615 40.703 -73.884 1.00 27.88 ? 347 PRO B O 1 ATOM 6284 C CB . PRO B 1 339 ? 186.062 43.113 -72.836 1.00 26.08 ? 347 PRO B CB 1 ATOM 6285 C CG . PRO B 1 339 ? 185.955 43.467 -71.387 1.00 25.08 ? 347 PRO B CG 1 ATOM 6286 C CD . PRO B 1 339 ? 186.617 42.290 -70.726 1.00 24.69 ? 347 PRO B CD 1 ATOM 6287 N N . VAL B 1 340 ? 185.649 40.382 -74.921 1.00 27.62 ? 348 VAL B N 1 ATOM 6288 C CA . VAL B 1 340 ? 186.240 39.616 -76.010 1.00 27.56 ? 348 VAL B CA 1 ATOM 6289 C C . VAL B 1 340 ? 186.025 40.340 -77.343 1.00 28.09 ? 348 VAL B C 1 ATOM 6290 O O . VAL B 1 340 ? 185.065 41.102 -77.489 1.00 27.22 ? 348 VAL B O 1 ATOM 6291 C CB . VAL B 1 340 ? 185.612 38.204 -76.067 1.00 26.54 ? 348 VAL B CB 1 ATOM 6292 C CG1 . VAL B 1 340 ? 184.111 38.304 -76.313 1.00 25.58 ? 348 VAL B CG1 1 ATOM 6293 C CG2 . VAL B 1 340 ? 186.273 37.394 -77.148 1.00 29.61 ? 348 VAL B CG2 1 ATOM 6294 N N . LYS B 1 341 ? 186.915 40.125 -78.310 1.00 28.95 ? 349 LYS B N 1 ATOM 6295 C CA . LYS B 1 341 ? 186.749 40.780 -79.599 1.00 30.91 ? 349 LYS B CA 1 ATOM 6296 C C . LYS B 1 341 ? 185.510 40.199 -80.275 1.00 30.71 ? 349 LYS B C 1 ATOM 6297 O O . LYS B 1 341 ? 185.314 38.982 -80.287 1.00 31.58 ? 349 LYS B O 1 ATOM 6298 C CB . LYS B 1 341 ? 187.980 40.575 -80.481 1.00 33.16 ? 349 LYS B CB 1 ATOM 6299 C CG . LYS B 1 341 ? 187.944 41.438 -81.756 1.00 40.20 ? 349 LYS B CG 1 ATOM 6300 C CD . LYS B 1 341 ? 189.287 41.463 -82.495 1.00 44.35 ? 349 LYS B CD 1 ATOM 6301 C CE . LYS B 1 341 ? 190.383 42.144 -81.667 1.00 45.92 ? 349 LYS B CE 1 ATOM 6302 N NZ . LYS B 1 341 ? 190.710 41.403 -80.405 1.00 44.44 ? 349 LYS B NZ 1 ATOM 6303 N N . ASP B 1 342 ? 184.678 41.073 -80.831 1.00 29.65 ? 350 ASP B N 1 ATOM 6304 C CA . ASP B 1 342 ? 183.437 40.661 -81.480 1.00 29.08 ? 350 ASP B CA 1 ATOM 6305 C C . ASP B 1 342 ? 183.207 41.512 -82.732 1.00 30.04 ? 350 ASP B C 1 ATOM 6306 O O . ASP B 1 342 ? 183.035 42.729 -82.637 1.00 29.89 ? 350 ASP B O 1 ATOM 6307 C CB . ASP B 1 342 ? 182.273 40.857 -80.503 1.00 28.48 ? 350 ASP B CB 1 ATOM 6308 C CG . ASP B 1 342 ? 181.005 40.144 -80.935 1.00 28.41 ? 350 ASP B CG 1 ATOM 6309 O OD1 . ASP B 1 342 ? 180.807 39.950 -82.154 1.00 29.28 ? 350 ASP B OD1 1 ATOM 6310 O OD2 . ASP B 1 342 ? 180.198 39.793 -80.040 1.00 27.10 ? 350 ASP B OD2 1 ATOM 6311 N N . GLN B 1 343 ? 183.201 40.874 -83.899 1.00 30.39 ? 351 GLN B N 1 ATOM 6312 C CA . GLN B 1 343 ? 182.997 41.587 -85.162 1.00 31.09 ? 351 GLN B CA 1 ATOM 6313 C C . GLN B 1 343 ? 181.560 42.065 -85.351 1.00 29.69 ? 351 GLN B C 1 ATOM 6314 O O . GLN B 1 343 ? 181.252 42.819 -86.285 1.00 28.72 ? 351 GLN B O 1 ATOM 6315 C CB . GLN B 1 343 ? 183.390 40.693 -86.342 1.00 33.49 ? 351 GLN B CB 1 ATOM 6316 C CG . GLN B 1 343 ? 184.878 40.403 -86.418 1.00 38.74 ? 351 GLN B CG 1 ATOM 6317 C CD . GLN B 1 343 ? 185.710 41.674 -86.442 1.00 41.41 ? 351 GLN B CD 1 ATOM 6318 O OE1 . GLN B 1 343 ? 185.506 42.542 -87.292 1.00 44.78 ? 351 GLN B OE1 1 ATOM 6319 N NE2 . GLN B 1 343 ? 186.655 41.790 -85.508 1.00 42.49 ? 351 GLN B NE2 1 ATOM 6320 N N . SER B 1 344 ? 180.685 41.615 -84.464 1.00 27.44 ? 352 SER B N 1 ATOM 6321 C CA . SER B 1 344 ? 179.285 41.982 -84.530 1.00 27.00 ? 352 SER B CA 1 ATOM 6322 C C . SER B 1 344 ? 179.029 43.214 -83.653 1.00 26.10 ? 352 SER B C 1 ATOM 6323 O O . SER B 1 344 ? 178.045 43.933 -83.835 1.00 25.52 ? 352 SER B O 1 ATOM 6324 C CB . SER B 1 344 ? 178.435 40.792 -84.072 1.00 27.63 ? 352 SER B CB 1 ATOM 6325 O OG . SER B 1 344 ? 177.057 41.083 -84.161 1.00 33.40 ? 352 SER B OG 1 ATOM 6326 N N . ALA B 1 345 ? 179.945 43.461 -82.722 1.00 24.02 ? 353 ALA B N 1 ATOM 6327 C CA . ALA B 1 345 ? 179.838 44.580 -81.796 1.00 22.36 ? 353 ALA B CA 1 ATOM 6328 C C . ALA B 1 345 ? 180.276 45.913 -82.380 1.00 22.06 ? 353 ALA B C 1 ATOM 6329 O O . ALA B 1 345 ? 181.072 45.969 -83.316 1.00 22.51 ? 353 ALA B O 1 ATOM 6330 C CB . ALA B 1 345 ? 180.651 44.289 -80.546 1.00 23.97 ? 353 ALA B CB 1 ATOM 6331 N N . PRO B 1 346 ? 179.756 47.016 -81.822 1.00 21.05 ? 354 PRO B N 1 ATOM 6332 C CA . PRO B 1 346 ? 180.120 48.348 -82.306 1.00 20.38 ? 354 PRO B CA 1 ATOM 6333 C C . PRO B 1 346 ? 181.483 48.783 -81.783 1.00 19.38 ? 354 PRO B C 1 ATOM 6334 O O . PRO B 1 346 ? 182.104 48.097 -80.972 1.00 18.50 ? 354 PRO B O 1 ATOM 6335 C CB . PRO B 1 346 ? 179.013 49.226 -81.738 1.00 19.19 ? 354 PRO B CB 1 ATOM 6336 C CG . PRO B 1 346 ? 178.725 48.564 -80.435 1.00 18.82 ? 354 PRO B CG 1 ATOM 6337 C CD . PRO B 1 346 ? 178.676 47.102 -80.821 1.00 19.06 ? 354 PRO B CD 1 ATOM 6338 N N . VAL B 1 347 ? 181.944 49.926 -82.275 1.00 18.98 ? 355 VAL B N 1 ATOM 6339 C CA . VAL B 1 347 ? 183.192 50.521 -81.817 1.00 18.71 ? 355 VAL B CA 1 ATOM 6340 C C . VAL B 1 347 ? 182.719 51.635 -80.889 1.00 20.03 ? 355 VAL B C 1 ATOM 6341 O O . VAL B 1 347 ? 181.837 52.419 -81.269 1.00 20.76 ? 355 VAL B O 1 ATOM 6342 C CB . VAL B 1 347 ? 183.987 51.186 -82.954 1.00 18.18 ? 355 VAL B CB 1 ATOM 6343 C CG1 . VAL B 1 347 ? 185.080 52.079 -82.352 1.00 16.04 ? 355 VAL B CG1 1 ATOM 6344 C CG2 . VAL B 1 347 ? 184.597 50.132 -83.858 1.00 16.35 ? 355 VAL B CG2 1 ATOM 6345 N N . TYR B 1 348 ? 183.278 51.704 -79.681 1.00 19.61 ? 356 TYR B N 1 ATOM 6346 C CA . TYR B 1 348 ? 182.885 52.739 -78.735 1.00 17.76 ? 356 TYR B CA 1 ATOM 6347 C C . TYR B 1 348 ? 183.936 53.821 -78.772 1.00 17.77 ? 356 TYR B C 1 ATOM 6348 O O . TYR B 1 348 ? 185.132 53.530 -78.716 1.00 18.38 ? 356 TYR B O 1 ATOM 6349 C CB . TYR B 1 348 ? 182.771 52.178 -77.314 1.00 17.46 ? 356 TYR B CB 1 ATOM 6350 C CG . TYR B 1 348 ? 181.712 51.110 -77.155 1.00 16.26 ? 356 TYR B CG 1 ATOM 6351 C CD1 . TYR B 1 348 ? 181.971 49.788 -77.511 1.00 15.59 ? 356 TYR B CD1 1 ATOM 6352 C CD2 . TYR B 1 348 ? 180.438 51.429 -76.683 1.00 16.64 ? 356 TYR B CD2 1 ATOM 6353 C CE1 . TYR B 1 348 ? 180.992 48.809 -77.402 1.00 15.61 ? 356 TYR B CE1 1 ATOM 6354 C CE2 . TYR B 1 348 ? 179.448 50.455 -76.573 1.00 15.68 ? 356 TYR B CE2 1 ATOM 6355 C CZ . TYR B 1 348 ? 179.735 49.151 -76.936 1.00 16.07 ? 356 TYR B CZ 1 ATOM 6356 O OH . TYR B 1 348 ? 178.764 48.184 -76.842 1.00 16.83 ? 356 TYR B OH 1 ATOM 6357 N N . ILE B 1 349 ? 183.481 55.068 -78.871 1.00 17.37 ? 357 ILE B N 1 ATOM 6358 C CA . ILE B 1 349 ? 184.372 56.219 -78.925 1.00 16.59 ? 357 ILE B CA 1 ATOM 6359 C C . ILE B 1 349 ? 184.017 57.307 -77.901 1.00 17.57 ? 357 ILE B C 1 ATOM 6360 O O . ILE B 1 349 ? 182.907 57.828 -77.917 1.00 19.09 ? 357 ILE B O 1 ATOM 6361 C CB . ILE B 1 349 ? 184.356 56.852 -80.341 1.00 14.25 ? 357 ILE B CB 1 ATOM 6362 C CG1 . ILE B 1 349 ? 185.103 55.949 -81.328 1.00 14.68 ? 357 ILE B CG1 1 ATOM 6363 C CG2 . ILE B 1 349 ? 184.965 58.249 -80.295 1.00 14.42 ? 357 ILE B CG2 1 ATOM 6364 C CD1 . ILE B 1 349 ? 185.180 56.493 -82.742 1.00 12.74 ? 357 ILE B CD1 1 ATOM 6365 N N . THR B 1 350 ? 184.957 57.637 -77.014 1.00 17.49 ? 358 THR B N 1 ATOM 6366 C CA . THR B 1 350 ? 184.762 58.701 -76.025 1.00 17.57 ? 358 THR B CA 1 ATOM 6367 C C . THR B 1 350 ? 185.339 59.957 -76.670 1.00 18.40 ? 358 THR B C 1 ATOM 6368 O O . THR B 1 350 ? 186.540 60.022 -76.962 1.00 18.24 ? 358 THR B O 1 ATOM 6369 C CB . THR B 1 350 ? 185.533 58.426 -74.728 1.00 18.24 ? 358 THR B CB 1 ATOM 6370 O OG1 . THR B 1 350 ? 185.001 57.255 -74.097 1.00 19.54 ? 358 THR B OG1 1 ATOM 6371 C CG2 . THR B 1 350 ? 185.410 59.604 -73.774 1.00 17.90 ? 358 THR B CG2 1 ATOM 6372 N N . ILE B 1 351 ? 184.484 60.950 -76.892 1.00 18.84 ? 359 ILE B N 1 ATOM 6373 C CA . ILE B 1 351 ? 184.890 62.193 -77.545 1.00 17.97 ? 359 ILE B CA 1 ATOM 6374 C C . ILE B 1 351 ? 184.375 63.405 -76.761 1.00 18.45 ? 359 ILE B C 1 ATOM 6375 O O . ILE B 1 351 ? 183.814 64.338 -77.332 1.00 18.71 ? 359 ILE B O 1 ATOM 6376 C CB . ILE B 1 351 ? 184.340 62.218 -79.014 1.00 17.32 ? 359 ILE B CB 1 ATOM 6377 C CG1 . ILE B 1 351 ? 184.897 63.412 -79.791 1.00 17.75 ? 359 ILE B CG1 1 ATOM 6378 C CG2 . ILE B 1 351 ? 182.820 62.262 -79.007 1.00 15.02 ? 359 ILE B CG2 1 ATOM 6379 C CD1 . ILE B 1 351 ? 186.318 63.232 -80.256 1.00 18.26 ? 359 ILE B CD1 1 ATOM 6380 N N . GLY B 1 352 ? 184.562 63.384 -75.444 1.00 19.16 ? 360 GLY B N 1 ATOM 6381 C CA . GLY B 1 352 ? 184.105 64.492 -74.619 1.00 19.12 ? 360 GLY B CA 1 ATOM 6382 C C . GLY B 1 352 ? 185.222 65.433 -74.212 1.00 20.39 ? 360 GLY B C 1 ATOM 6383 O O . GLY B 1 352 ? 185.285 65.880 -73.064 1.00 20.80 ? 360 GLY B O 1 ATOM 6384 N N . ASP B 1 353 ? 186.092 65.755 -75.164 1.00 21.39 ? 361 ASP B N 1 ATOM 6385 C CA . ASP B 1 353 ? 187.243 66.620 -74.912 1.00 21.86 ? 361 ASP B CA 1 ATOM 6386 C C . ASP B 1 353 ? 187.181 67.944 -75.660 1.00 21.85 ? 361 ASP B C 1 ATOM 6387 O O . ASP B 1 353 ? 188.219 68.470 -76.064 1.00 22.79 ? 361 ASP B O 1 ATOM 6388 C CB . ASP B 1 353 ? 188.528 65.880 -75.307 1.00 22.42 ? 361 ASP B CB 1 ATOM 6389 C CG . ASP B 1 353 ? 188.543 65.470 -76.777 1.00 22.90 ? 361 ASP B CG 1 ATOM 6390 O OD1 . ASP B 1 353 ? 187.522 64.941 -77.254 1.00 24.10 ? 361 ASP B OD1 1 ATOM 6391 O OD2 . ASP B 1 353 ? 189.576 65.664 -77.458 1.00 24.14 ? 361 ASP B OD2 1 ATOM 6392 N N . ALA B 1 354 ? 185.977 68.484 -75.841 1.00 21.86 ? 362 ALA B N 1 ATOM 6393 C CA . ALA B 1 354 ? 185.804 69.749 -76.557 1.00 20.72 ? 362 ALA B CA 1 ATOM 6394 C C . ALA B 1 354 ? 186.271 70.973 -75.759 1.00 21.81 ? 362 ALA B C 1 ATOM 6395 O O . ALA B 1 354 ? 186.487 72.043 -76.335 1.00 21.58 ? 362 ALA B O 1 ATOM 6396 C CB . ALA B 1 354 ? 184.351 69.923 -76.969 1.00 19.49 ? 362 ALA B CB 1 ATOM 6397 N N . GLY B 1 355 ? 186.418 70.833 -74.443 1.00 20.82 ? 363 GLY B N 1 ATOM 6398 C CA . GLY B 1 355 ? 186.885 71.966 -73.667 1.00 21.04 ? 363 GLY B CA 1 ATOM 6399 C C . GLY B 1 355 ? 186.397 72.139 -72.241 1.00 21.58 ? 363 GLY B C 1 ATOM 6400 O O . GLY B 1 355 ? 187.186 72.498 -71.361 1.00 19.25 ? 363 GLY B O 1 ATOM 6401 N N . ASN B 1 356 ? 185.116 71.867 -72.002 1.00 22.43 ? 364 ASN B N 1 ATOM 6402 C CA . ASN B 1 356 ? 184.509 72.050 -70.678 1.00 24.41 ? 364 ASN B CA 1 ATOM 6403 C C . ASN B 1 356 ? 185.033 73.342 -70.014 1.00 25.16 ? 364 ASN B C 1 ATOM 6404 O O . ASN B 1 356 ? 185.121 74.378 -70.683 1.00 25.09 ? 364 ASN B O 1 ATOM 6405 C CB . ASN B 1 356 ? 184.699 70.796 -69.778 1.00 24.10 ? 364 ASN B CB 1 ATOM 6406 C CG . ASN B 1 356 ? 186.148 70.529 -69.389 1.00 25.04 ? 364 ASN B CG 1 ATOM 6407 O OD1 . ASN B 1 356 ? 186.651 71.077 -68.405 1.00 25.33 ? 364 ASN B OD1 1 ATOM 6408 N ND2 . ASN B 1 356 ? 186.822 69.673 -70.155 1.00 23.34 ? 364 ASN B ND2 1 ATOM 6409 N N . TYR B 1 357 ? 185.357 73.323 -68.726 1.00 25.47 ? 365 TYR B N 1 ATOM 6410 C CA . TYR B 1 357 ? 185.859 74.546 -68.110 1.00 26.14 ? 365 TYR B CA 1 ATOM 6411 C C . TYR B 1 357 ? 187.382 74.614 -68.136 1.00 26.64 ? 365 TYR B C 1 ATOM 6412 O O . TYR B 1 357 ? 187.995 75.275 -67.310 1.00 27.30 ? 365 TYR B O 1 ATOM 6413 C CB . TYR B 1 357 ? 185.340 74.692 -66.676 1.00 26.78 ? 365 TYR B CB 1 ATOM 6414 C CG . TYR B 1 357 ? 185.388 73.420 -65.862 1.00 28.40 ? 365 TYR B CG 1 ATOM 6415 C CD1 . TYR B 1 357 ? 184.399 72.442 -66.001 1.00 27.26 ? 365 TYR B CD1 1 ATOM 6416 C CD2 . TYR B 1 357 ? 186.434 73.182 -64.967 1.00 28.12 ? 365 TYR B CD2 1 ATOM 6417 C CE1 . TYR B 1 357 ? 184.450 71.263 -65.276 1.00 27.85 ? 365 TYR B CE1 1 ATOM 6418 C CE2 . TYR B 1 357 ? 186.494 72.003 -64.236 1.00 29.20 ? 365 TYR B CE2 1 ATOM 6419 C CZ . TYR B 1 357 ? 185.500 71.048 -64.398 1.00 29.45 ? 365 TYR B CZ 1 ATOM 6420 O OH . TYR B 1 357 ? 185.567 69.868 -63.695 1.00 34.02 ? 365 TYR B OH 1 ATOM 6421 N N . GLY B 1 358 ? 187.984 73.911 -69.091 1.00 27.87 ? 366 GLY B N 1 ATOM 6422 C CA . GLY B 1 358 ? 189.428 73.930 -69.243 1.00 27.70 ? 366 GLY B CA 1 ATOM 6423 C C . GLY B 1 358 ? 190.223 72.815 -68.593 1.00 28.90 ? 366 GLY B C 1 ATOM 6424 O O . GLY B 1 358 ? 191.452 72.916 -68.492 1.00 28.36 ? 366 GLY B O 1 ATOM 6425 N N . VAL B 1 359 ? 189.556 71.754 -68.149 1.00 28.40 ? 367 VAL B N 1 ATOM 6426 C CA . VAL B 1 359 ? 190.279 70.655 -67.522 1.00 28.22 ? 367 VAL B CA 1 ATOM 6427 C C . VAL B 1 359 ? 190.254 69.386 -68.360 1.00 29.59 ? 367 VAL B C 1 ATOM 6428 O O . VAL B 1 359 ? 189.225 69.012 -68.917 1.00 30.88 ? 367 VAL B O 1 ATOM 6429 C CB . VAL B 1 359 ? 189.739 70.354 -66.120 1.00 27.08 ? 367 VAL B CB 1 ATOM 6430 C CG1 . VAL B 1 359 ? 190.492 69.178 -65.512 1.00 26.19 ? 367 VAL B CG1 1 ATOM 6431 C CG2 . VAL B 1 359 ? 189.911 71.582 -65.245 1.00 25.91 ? 367 VAL B CG2 1 ATOM 6432 N N . ILE B 1 360 ? 191.410 68.734 -68.431 1.00 30.14 ? 368 ILE B N 1 ATOM 6433 C CA . ILE B 1 360 ? 191.600 67.516 -69.206 1.00 29.54 ? 368 ILE B CA 1 ATOM 6434 C C . ILE B 1 360 ? 191.787 66.318 -68.271 1.00 30.05 ? 368 ILE B C 1 ATOM 6435 O O . ILE B 1 360 ? 192.399 66.457 -67.217 1.00 31.14 ? 368 ILE B O 1 ATOM 6436 C CB . ILE B 1 360 ? 192.846 67.692 -70.115 1.00 28.84 ? 368 ILE B CB 1 ATOM 6437 C CG1 . ILE B 1 360 ? 192.455 67.544 -71.578 1.00 30.83 ? 368 ILE B CG1 1 ATOM 6438 C CG2 . ILE B 1 360 ? 193.926 66.708 -69.747 1.00 28.93 ? 368 ILE B CG2 1 ATOM 6439 C CD1 . ILE B 1 360 ? 191.991 66.167 -71.935 1.00 32.14 ? 368 ILE B CD1 1 ATOM 6440 N N . ASP B 1 361 ? 191.248 65.153 -68.632 1.00 30.20 ? 369 ASP B N 1 ATOM 6441 C CA . ASP B 1 361 ? 191.422 63.954 -67.801 1.00 30.62 ? 369 ASP B CA 1 ATOM 6442 C C . ASP B 1 361 ? 192.669 63.226 -68.309 1.00 31.50 ? 369 ASP B C 1 ATOM 6443 O O . ASP B 1 361 ? 192.675 62.711 -69.427 1.00 32.44 ? 369 ASP B O 1 ATOM 6444 C CB . ASP B 1 361 ? 190.212 63.018 -67.905 1.00 30.53 ? 369 ASP B CB 1 ATOM 6445 C CG . ASP B 1 361 ? 188.968 63.579 -67.241 1.00 31.11 ? 369 ASP B CG 1 ATOM 6446 O OD1 . ASP B 1 361 ? 189.071 64.108 -66.116 1.00 30.95 ? 369 ASP B OD1 1 ATOM 6447 O OD2 . ASP B 1 361 ? 187.877 63.475 -67.839 1.00 33.86 ? 369 ASP B OD2 1 ATOM 6448 N N . SER B 1 362 ? 193.718 63.176 -67.491 1.00 32.31 ? 370 SER B N 1 ATOM 6449 C CA . SER B 1 362 ? 194.979 62.546 -67.898 1.00 33.06 ? 370 SER B CA 1 ATOM 6450 C C . SER B 1 362 ? 195.200 61.186 -67.291 1.00 32.87 ? 370 SER B C 1 ATOM 6451 O O . SER B 1 362 ? 195.732 60.278 -67.923 1.00 33.84 ? 370 SER B O 1 ATOM 6452 C CB . SER B 1 362 ? 196.164 63.419 -67.495 1.00 32.79 ? 370 SER B CB 1 ATOM 6453 O OG . SER B 1 362 ? 195.995 64.746 -67.939 1.00 36.19 ? 370 SER B OG 1 ATOM 6454 N N . ASN B 1 363 ? 194.810 61.070 -66.036 1.00 33.23 ? 371 ASN B N 1 ATOM 6455 C CA . ASN B 1 363 ? 194.977 59.846 -65.293 1.00 33.51 ? 371 ASN B CA 1 ATOM 6456 C C . ASN B 1 363 ? 194.177 58.712 -65.934 1.00 32.91 ? 371 ASN B C 1 ATOM 6457 O O . ASN B 1 363 ? 192.945 58.727 -65.934 1.00 33.11 ? 371 ASN B O 1 ATOM 6458 C CB . ASN B 1 363 ? 194.539 60.102 -63.854 1.00 35.49 ? 371 ASN B CB 1 ATOM 6459 C CG . ASN B 1 363 ? 194.868 58.965 -62.937 1.00 39.75 ? 371 ASN B CG 1 ATOM 6460 O OD1 . ASN B 1 363 ? 195.740 58.142 -63.224 1.00 42.21 ? 371 ASN B OD1 1 ATOM 6461 N ND2 . ASN B 1 363 ? 194.179 58.914 -61.805 1.00 42.65 ? 371 ASN B ND2 1 ATOM 6462 N N . MET B 1 364 ? 194.881 57.737 -66.500 1.00 31.38 ? 372 MET B N 1 ATOM 6463 C CA . MET B 1 364 ? 194.216 56.601 -67.129 1.00 31.87 ? 372 MET B CA 1 ATOM 6464 C C . MET B 1 364 ? 194.674 55.257 -66.561 1.00 30.94 ? 372 MET B C 1 ATOM 6465 O O . MET B 1 364 ? 195.785 55.136 -66.049 1.00 31.80 ? 372 MET B O 1 ATOM 6466 C CB . MET B 1 364 ? 194.413 56.642 -68.653 1.00 31.51 ? 372 MET B CB 1 ATOM 6467 C CG . MET B 1 364 ? 195.782 57.109 -69.103 1.00 32.37 ? 372 MET B CG 1 ATOM 6468 S SD . MET B 1 364 ? 195.914 57.328 -70.893 1.00 31.45 ? 372 MET B SD 1 ATOM 6469 C CE . MET B 1 364 ? 195.338 59.009 -71.108 1.00 32.02 ? 372 MET B CE 1 ATOM 6470 N N . ILE B 1 365 ? 193.789 54.262 -66.635 1.00 30.57 ? 373 ILE B N 1 ATOM 6471 C CA . ILE B 1 365 ? 194.057 52.911 -66.140 1.00 27.85 ? 373 ILE B CA 1 ATOM 6472 C C . ILE B 1 365 ? 195.286 52.339 -66.836 1.00 28.26 ? 373 ILE B C 1 ATOM 6473 O O . ILE B 1 365 ? 195.418 52.420 -68.057 1.00 27.19 ? 373 ILE B O 1 ATOM 6474 C CB . ILE B 1 365 ? 192.867 51.946 -66.422 1.00 26.60 ? 373 ILE B CB 1 ATOM 6475 C CG1 . ILE B 1 365 ? 191.570 52.493 -65.818 1.00 25.13 ? 373 ILE B CG1 1 ATOM 6476 C CG2 . ILE B 1 365 ? 193.175 50.566 -65.870 1.00 22.50 ? 373 ILE B CG2 1 ATOM 6477 C CD1 . ILE B 1 365 ? 191.584 52.607 -64.327 1.00 26.12 ? 373 ILE B CD1 1 ATOM 6478 N N . GLN B 1 366 ? 196.178 51.747 -66.050 1.00 29.01 ? 374 GLN B N 1 ATOM 6479 C CA . GLN B 1 366 ? 197.395 51.156 -66.584 1.00 29.44 ? 374 GLN B CA 1 ATOM 6480 C C . GLN B 1 366 ? 197.504 49.691 -66.167 1.00 28.77 ? 374 GLN B C 1 ATOM 6481 O O . GLN B 1 366 ? 197.170 49.332 -65.039 1.00 29.87 ? 374 GLN B O 1 ATOM 6482 C CB . GLN B 1 366 ? 198.612 51.909 -66.052 1.00 31.83 ? 374 GLN B CB 1 ATOM 6483 C CG . GLN B 1 366 ? 199.611 52.278 -67.111 1.00 35.98 ? 374 GLN B CG 1 ATOM 6484 C CD . GLN B 1 366 ? 199.096 53.382 -67.992 1.00 37.91 ? 374 GLN B CD 1 ATOM 6485 O OE1 . GLN B 1 366 ? 198.766 54.463 -67.509 1.00 40.23 ? 374 GLN B OE1 1 ATOM 6486 N NE2 . GLN B 1 366 ? 199.020 53.121 -69.295 1.00 40.71 ? 374 GLN B NE2 1 ATOM 6487 N N . PRO B 1 367 ? 197.947 48.817 -67.077 1.00 28.09 ? 375 PRO B N 1 ATOM 6488 C CA . PRO B 1 367 ? 198.338 49.147 -68.445 1.00 27.81 ? 375 PRO B CA 1 ATOM 6489 C C . PRO B 1 367 ? 197.082 49.307 -69.290 1.00 28.19 ? 375 PRO B C 1 ATOM 6490 O O . PRO B 1 367 ? 195.980 48.972 -68.851 1.00 28.55 ? 375 PRO B O 1 ATOM 6491 C CB . PRO B 1 367 ? 199.161 47.938 -68.865 1.00 26.68 ? 375 PRO B CB 1 ATOM 6492 C CG . PRO B 1 367 ? 198.475 46.828 -68.147 1.00 27.27 ? 375 PRO B CG 1 ATOM 6493 C CD . PRO B 1 367 ? 198.264 47.411 -66.772 1.00 27.42 ? 375 PRO B CD 1 ATOM 6494 N N . GLN B 1 368 ? 197.248 49.824 -70.498 1.00 27.48 ? 376 GLN B N 1 ATOM 6495 C CA . GLN B 1 368 ? 196.114 50.013 -71.381 1.00 27.29 ? 376 GLN B CA 1 ATOM 6496 C C . GLN B 1 368 ? 195.453 48.664 -71.630 1.00 26.31 ? 376 GLN B C 1 ATOM 6497 O O . GLN B 1 368 ? 196.100 47.720 -72.071 1.00 26.33 ? 376 GLN B O 1 ATOM 6498 C CB . GLN B 1 368 ? 196.586 50.627 -72.691 1.00 27.28 ? 376 GLN B CB 1 ATOM 6499 C CG . GLN B 1 368 ? 195.490 50.877 -73.687 1.00 29.54 ? 376 GLN B CG 1 ATOM 6500 C CD . GLN B 1 368 ? 196.001 51.608 -74.901 1.00 30.92 ? 376 GLN B CD 1 ATOM 6501 O OE1 . GLN B 1 368 ? 195.250 51.899 -75.832 1.00 30.53 ? 376 GLN B OE1 1 ATOM 6502 N NE2 . GLN B 1 368 ? 197.293 51.916 -74.899 1.00 32.73 ? 376 GLN B NE2 1 ATOM 6503 N N . PRO B 1 369 ? 194.155 48.550 -71.327 1.00 26.13 ? 377 PRO B N 1 ATOM 6504 C CA . PRO B 1 369 ? 193.441 47.288 -71.535 1.00 26.62 ? 377 PRO B CA 1 ATOM 6505 C C . PRO B 1 369 ? 193.420 46.884 -73.002 1.00 27.49 ? 377 PRO B C 1 ATOM 6506 O O . PRO B 1 369 ? 193.700 47.699 -73.878 1.00 28.27 ? 377 PRO B O 1 ATOM 6507 C CB . PRO B 1 369 ? 192.049 47.579 -70.974 1.00 26.68 ? 377 PRO B CB 1 ATOM 6508 C CG . PRO B 1 369 ? 191.909 49.059 -71.158 1.00 27.80 ? 377 PRO B CG 1 ATOM 6509 C CD . PRO B 1 369 ? 193.265 49.579 -70.765 1.00 26.53 ? 377 PRO B CD 1 ATOM 6510 N N . GLU B 1 370 ? 193.089 45.623 -73.262 1.00 28.62 ? 378 GLU B N 1 ATOM 6511 C CA . GLU B 1 370 ? 193.046 45.103 -74.622 1.00 29.00 ? 378 GLU B CA 1 ATOM 6512 C C . GLU B 1 370 ? 191.935 45.693 -75.475 1.00 27.03 ? 378 GLU B C 1 ATOM 6513 O O . GLU B 1 370 ? 192.095 45.848 -76.689 1.00 27.59 ? 378 GLU B O 1 ATOM 6514 C CB . GLU B 1 370 ? 192.876 43.589 -74.600 1.00 32.87 ? 378 GLU B CB 1 ATOM 6515 C CG . GLU B 1 370 ? 194.093 42.805 -75.033 1.00 41.44 ? 378 GLU B CG 1 ATOM 6516 C CD . GLU B 1 370 ? 193.716 41.410 -75.505 1.00 47.56 ? 378 GLU B CD 1 ATOM 6517 O OE1 . GLU B 1 370 ? 193.104 41.305 -76.594 1.00 49.60 ? 378 GLU B OE1 1 ATOM 6518 O OE2 . GLU B 1 370 ? 194.014 40.426 -74.784 1.00 50.24 ? 378 GLU B OE2 1 ATOM 6519 N N . TYR B 1 371 ? 190.805 46.000 -74.847 1.00 25.27 ? 379 TYR B N 1 ATOM 6520 C CA . TYR B 1 371 ? 189.661 46.539 -75.570 1.00 24.76 ? 379 TYR B CA 1 ATOM 6521 C C . TYR B 1 371 ? 189.855 47.987 -76.016 1.00 24.96 ? 379 TYR B C 1 ATOM 6522 O O . TYR B 1 371 ? 189.052 48.523 -76.784 1.00 25.27 ? 379 TYR B O 1 ATOM 6523 C CB . TYR B 1 371 ? 188.389 46.394 -74.719 1.00 24.56 ? 379 TYR B CB 1 ATOM 6524 C CG . TYR B 1 371 ? 188.396 47.160 -73.417 1.00 24.65 ? 379 TYR B CG 1 ATOM 6525 C CD1 . TYR B 1 371 ? 188.193 48.542 -73.390 1.00 25.32 ? 379 TYR B CD1 1 ATOM 6526 C CD2 . TYR B 1 371 ? 188.604 46.505 -72.210 1.00 25.08 ? 379 TYR B CD2 1 ATOM 6527 C CE1 . TYR B 1 371 ? 188.196 49.253 -72.183 1.00 25.48 ? 379 TYR B CE1 1 ATOM 6528 C CE2 . TYR B 1 371 ? 188.615 47.202 -71.000 1.00 25.84 ? 379 TYR B CE2 1 ATOM 6529 C CZ . TYR B 1 371 ? 188.411 48.577 -70.992 1.00 25.91 ? 379 TYR B CZ 1 ATOM 6530 O OH . TYR B 1 371 ? 188.448 49.280 -69.800 1.00 24.71 ? 379 TYR B OH 1 ATOM 6531 N N . SER B 1 372 ? 190.934 48.614 -75.559 1.00 24.64 ? 380 SER B N 1 ATOM 6532 C CA . SER B 1 372 ? 191.210 50.000 -75.927 1.00 24.68 ? 380 SER B CA 1 ATOM 6533 C C . SER B 1 372 ? 192.165 50.075 -77.110 1.00 24.17 ? 380 SER B C 1 ATOM 6534 O O . SER B 1 372 ? 193.308 49.638 -77.015 1.00 25.69 ? 380 SER B O 1 ATOM 6535 C CB . SER B 1 372 ? 191.817 50.751 -74.742 1.00 24.67 ? 380 SER B CB 1 ATOM 6536 O OG . SER B 1 372 ? 191.982 52.124 -75.051 1.00 24.46 ? 380 SER B OG 1 ATOM 6537 N N . ALA B 1 373 ? 191.701 50.640 -78.219 1.00 23.36 ? 381 ALA B N 1 ATOM 6538 C CA . ALA B 1 373 ? 192.526 50.747 -79.414 1.00 22.25 ? 381 ALA B CA 1 ATOM 6539 C C . ALA B 1 373 ? 193.451 51.953 -79.379 1.00 23.82 ? 381 ALA B C 1 ATOM 6540 O O . ALA B 1 373 ? 194.638 51.842 -79.691 1.00 24.20 ? 381 ALA B O 1 ATOM 6541 C CB . ALA B 1 373 ? 191.642 50.808 -80.651 1.00 22.42 ? 381 ALA B CB 1 ATOM 6542 N N . PHE B 1 374 ? 192.908 53.107 -79.009 1.00 23.60 ? 382 PHE B N 1 ATOM 6543 C CA . PHE B 1 374 ? 193.702 54.323 -78.955 1.00 24.32 ? 382 PHE B CA 1 ATOM 6544 C C . PHE B 1 374 ? 193.126 55.261 -77.899 1.00 25.03 ? 382 PHE B C 1 ATOM 6545 O O . PHE B 1 374 ? 191.914 55.310 -77.699 1.00 26.43 ? 382 PHE B O 1 ATOM 6546 C CB . PHE B 1 374 ? 193.701 54.980 -80.339 1.00 25.46 ? 382 PHE B CB 1 ATOM 6547 C CG . PHE B 1 374 ? 194.515 56.240 -80.419 1.00 28.24 ? 382 PHE B CG 1 ATOM 6548 C CD1 . PHE B 1 374 ? 194.011 57.447 -79.939 1.00 28.15 ? 382 PHE B CD1 1 ATOM 6549 C CD2 . PHE B 1 374 ? 195.799 56.217 -80.951 1.00 29.14 ? 382 PHE B CD2 1 ATOM 6550 C CE1 . PHE B 1 374 ? 194.776 58.613 -79.985 1.00 29.42 ? 382 PHE B CE1 1 ATOM 6551 C CE2 . PHE B 1 374 ? 196.571 57.377 -81.001 1.00 30.61 ? 382 PHE B CE2 1 ATOM 6552 C CZ . PHE B 1 374 ? 196.056 58.578 -80.515 1.00 30.57 ? 382 PHE B CZ 1 ATOM 6553 N N . ARG B 1 375 ? 193.994 55.993 -77.210 1.00 24.14 ? 383 ARG B N 1 ATOM 6554 C CA . ARG B 1 375 ? 193.553 56.924 -76.177 1.00 24.60 ? 383 ARG B CA 1 ATOM 6555 C C . ARG B 1 375 ? 194.577 58.028 -75.992 1.00 24.35 ? 383 ARG B C 1 ATOM 6556 O O . ARG B 1 375 ? 195.776 57.807 -76.135 1.00 24.79 ? 383 ARG B O 1 ATOM 6557 C CB . ARG B 1 375 ? 193.346 56.193 -74.844 1.00 25.03 ? 383 ARG B CB 1 ATOM 6558 C CG . ARG B 1 375 ? 194.362 55.102 -74.616 1.00 28.29 ? 383 ARG B CG 1 ATOM 6559 C CD . ARG B 1 375 ? 194.997 55.148 -73.247 1.00 28.95 ? 383 ARG B CD 1 ATOM 6560 N NE . ARG B 1 375 ? 194.335 54.274 -72.288 1.00 30.08 ? 383 ARG B NE 1 ATOM 6561 C CZ . ARG B 1 375 ? 194.950 53.700 -71.256 1.00 30.59 ? 383 ARG B CZ 1 ATOM 6562 N NH1 . ARG B 1 375 ? 196.247 53.898 -71.041 1.00 30.30 ? 383 ARG B NH1 1 ATOM 6563 N NH2 . ARG B 1 375 ? 194.265 52.928 -70.431 1.00 31.67 ? 383 ARG B NH2 1 ATOM 6564 N N . GLU B 1 376 ? 194.098 59.224 -75.683 1.00 24.41 ? 384 GLU B N 1 ATOM 6565 C CA . GLU B 1 376 ? 194.983 60.351 -75.458 1.00 25.22 ? 384 GLU B CA 1 ATOM 6566 C C . GLU B 1 376 ? 194.254 61.478 -74.761 1.00 24.76 ? 384 GLU B C 1 ATOM 6567 O O . GLU B 1 376 ? 193.114 61.794 -75.100 1.00 24.00 ? 384 GLU B O 1 ATOM 6568 C CB . GLU B 1 376 ? 195.563 60.867 -76.774 1.00 26.19 ? 384 GLU B CB 1 ATOM 6569 C CG . GLU B 1 376 ? 196.550 62.001 -76.560 1.00 27.21 ? 384 GLU B CG 1 ATOM 6570 C CD . GLU B 1 376 ? 197.110 62.535 -77.852 1.00 29.96 ? 384 GLU B CD 1 ATOM 6571 O OE1 . GLU B 1 376 ? 197.652 61.729 -78.637 1.00 31.58 ? 384 GLU B OE1 1 ATOM 6572 O OE2 . GLU B 1 376 ? 197.008 63.760 -78.082 1.00 31.47 ? 384 GLU B OE2 1 ATOM 6573 N N . ALA B 1 377 ? 194.930 62.090 -73.796 1.00 24.92 ? 385 ALA B N 1 ATOM 6574 C CA . ALA B 1 377 ? 194.353 63.184 -73.041 1.00 25.10 ? 385 ALA B CA 1 ATOM 6575 C C . ALA B 1 377 ? 194.598 64.540 -73.700 1.00 25.89 ? 385 ALA B C 1 ATOM 6576 O O . ALA B 1 377 ? 195.432 65.316 -73.231 1.00 27.87 ? 385 ALA B O 1 ATOM 6577 C CB . ALA B 1 377 ? 194.916 63.185 -71.631 1.00 23.09 ? 385 ALA B CB 1 ATOM 6578 N N . SER B 1 378 ? 193.881 64.828 -74.782 1.00 24.84 ? 386 SER B N 1 ATOM 6579 C CA . SER B 1 378 ? 194.024 66.117 -75.456 1.00 26.58 ? 386 SER B CA 1 ATOM 6580 C C . SER B 1 378 ? 192.665 66.669 -75.874 1.00 27.67 ? 386 SER B C 1 ATOM 6581 O O . SER B 1 378 ? 191.739 65.900 -76.142 1.00 28.40 ? 386 SER B O 1 ATOM 6582 C CB . SER B 1 378 ? 194.910 65.980 -76.694 1.00 26.29 ? 386 SER B CB 1 ATOM 6583 O OG . SER B 1 378 ? 196.206 65.545 -76.339 1.00 28.90 ? 386 SER B OG 1 ATOM 6584 N N . PHE B 1 379 ? 192.539 67.995 -75.916 1.00 27.82 ? 387 PHE B N 1 ATOM 6585 C CA . PHE B 1 379 ? 191.283 68.610 -76.339 1.00 28.28 ? 387 PHE B CA 1 ATOM 6586 C C . PHE B 1 379 ? 191.162 68.462 -77.852 1.00 28.39 ? 387 PHE B C 1 ATOM 6587 O O . PHE B 1 379 ? 192.160 68.262 -78.545 1.00 28.86 ? 387 PHE B O 1 ATOM 6588 C CB . PHE B 1 379 ? 191.247 70.097 -75.980 1.00 28.02 ? 387 PHE B CB 1 ATOM 6589 C CG . PHE B 1 379 ? 191.132 70.365 -74.510 1.00 30.70 ? 387 PHE B CG 1 ATOM 6590 C CD1 . PHE B 1 379 ? 190.056 69.867 -73.781 1.00 30.99 ? 387 PHE B CD1 1 ATOM 6591 C CD2 . PHE B 1 379 ? 192.092 71.134 -73.852 1.00 31.42 ? 387 PHE B CD2 1 ATOM 6592 C CE1 . PHE B 1 379 ? 189.936 70.128 -72.410 1.00 31.87 ? 387 PHE B CE1 1 ATOM 6593 C CE2 . PHE B 1 379 ? 191.982 71.401 -72.483 1.00 31.54 ? 387 PHE B CE2 1 ATOM 6594 C CZ . PHE B 1 379 ? 190.900 70.897 -71.763 1.00 31.86 ? 387 PHE B CZ 1 ATOM 6595 N N . GLY B 1 380 ? 189.943 68.568 -78.364 1.00 28.05 ? 388 GLY B N 1 ATOM 6596 C CA . GLY B 1 380 ? 189.733 68.441 -79.794 1.00 27.45 ? 388 GLY B CA 1 ATOM 6597 C C . GLY B 1 380 ? 188.314 68.004 -80.094 1.00 27.23 ? 388 GLY B C 1 ATOM 6598 O O . GLY B 1 380 ? 187.430 68.099 -79.234 1.00 27.82 ? 388 GLY B O 1 ATOM 6599 N N . HIS B 1 381 ? 188.087 67.542 -81.318 1.00 26.22 ? 389 HIS B N 1 ATOM 6600 C CA . HIS B 1 381 ? 186.769 67.075 -81.726 1.00 25.26 ? 389 HIS B CA 1 ATOM 6601 C C . HIS B 1 381 ? 186.972 65.977 -82.755 1.00 24.62 ? 389 HIS B C 1 ATOM 6602 O O . HIS B 1 381 ? 188.106 65.608 -83.047 1.00 26.03 ? 389 HIS B O 1 ATOM 6603 C CB . HIS B 1 381 ? 185.954 68.213 -82.345 1.00 25.87 ? 389 HIS B CB 1 ATOM 6604 C CG . HIS B 1 381 ? 186.495 68.698 -83.652 1.00 27.04 ? 389 HIS B CG 1 ATOM 6605 N ND1 . HIS B 1 381 ? 187.688 69.382 -83.756 1.00 28.06 ? 389 HIS B ND1 1 ATOM 6606 C CD2 . HIS B 1 381 ? 186.017 68.577 -84.914 1.00 26.75 ? 389 HIS B CD2 1 ATOM 6607 C CE1 . HIS B 1 381 ? 187.920 69.661 -85.026 1.00 28.41 ? 389 HIS B CE1 1 ATOM 6608 N NE2 . HIS B 1 381 ? 186.922 69.183 -85.750 1.00 27.82 ? 389 HIS B NE2 1 ATOM 6609 N N . GLY B 1 382 ? 185.880 65.461 -83.308 1.00 23.84 ? 390 GLY B N 1 ATOM 6610 C CA . GLY B 1 382 ? 185.993 64.404 -84.292 1.00 23.17 ? 390 GLY B CA 1 ATOM 6611 C C . GLY B 1 382 ? 185.078 64.615 -85.479 1.00 24.49 ? 390 GLY B C 1 ATOM 6612 O O . GLY B 1 382 ? 184.239 65.518 -85.479 1.00 25.48 ? 390 GLY B O 1 ATOM 6613 N N . MET B 1 383 ? 185.252 63.786 -86.501 1.00 25.02 ? 391 MET B N 1 ATOM 6614 C CA . MET B 1 383 ? 184.438 63.863 -87.703 1.00 26.46 ? 391 MET B CA 1 ATOM 6615 C C . MET B 1 383 ? 184.122 62.447 -88.158 1.00 26.11 ? 391 MET B C 1 ATOM 6616 O O . MET B 1 383 ? 185.010 61.585 -88.197 1.00 26.60 ? 391 MET B O 1 ATOM 6617 C CB . MET B 1 383 ? 185.193 64.588 -88.824 1.00 30.28 ? 391 MET B CB 1 ATOM 6618 C CG . MET B 1 383 ? 185.587 66.030 -88.524 1.00 36.28 ? 391 MET B CG 1 ATOM 6619 S SD . MET B 1 383 ? 184.190 67.187 -88.546 1.00 43.53 ? 391 MET B SD 1 ATOM 6620 C CE . MET B 1 383 ? 183.673 67.045 -90.268 1.00 40.73 ? 391 MET B CE 1 ATOM 6621 N N . PHE B 1 384 ? 182.856 62.204 -88.477 1.00 23.82 ? 392 PHE B N 1 ATOM 6622 C CA . PHE B 1 384 ? 182.425 60.903 -88.970 1.00 22.43 ? 392 PHE B CA 1 ATOM 6623 C C . PHE B 1 384 ? 181.951 61.229 -90.383 1.00 23.59 ? 392 PHE B C 1 ATOM 6624 O O . PHE B 1 384 ? 180.862 61.783 -90.573 1.00 23.20 ? 392 PHE B O 1 ATOM 6625 C CB . PHE B 1 384 ? 181.274 60.354 -88.123 1.00 20.27 ? 392 PHE B CB 1 ATOM 6626 C CG . PHE B 1 384 ? 180.996 58.893 -88.355 1.00 18.25 ? 392 PHE B CG 1 ATOM 6627 C CD1 . PHE B 1 384 ? 181.892 57.927 -87.914 1.00 18.28 ? 392 PHE B CD1 1 ATOM 6628 C CD2 . PHE B 1 384 ? 179.856 58.483 -89.042 1.00 18.15 ? 392 PHE B CD2 1 ATOM 6629 C CE1 . PHE B 1 384 ? 181.663 56.573 -88.151 1.00 16.88 ? 392 PHE B CE1 1 ATOM 6630 C CE2 . PHE B 1 384 ? 179.617 57.130 -89.287 1.00 17.21 ? 392 PHE B CE2 1 ATOM 6631 C CZ . PHE B 1 384 ? 180.524 56.173 -88.840 1.00 16.49 ? 392 PHE B CZ 1 ATOM 6632 N N . ASP B 1 385 ? 182.788 60.905 -91.365 1.00 24.00 ? 393 ASP B N 1 ATOM 6633 C CA . ASP B 1 385 ? 182.515 61.203 -92.765 1.00 24.34 ? 393 ASP B CA 1 ATOM 6634 C C . ASP B 1 385 ? 182.042 59.968 -93.523 1.00 24.32 ? 393 ASP B C 1 ATOM 6635 O O . ASP B 1 385 ? 182.840 59.084 -93.837 1.00 25.42 ? 393 ASP B O 1 ATOM 6636 C CB . ASP B 1 385 ? 183.797 61.782 -93.383 1.00 26.71 ? 393 ASP B CB 1 ATOM 6637 C CG . ASP B 1 385 ? 183.572 62.431 -94.739 1.00 29.12 ? 393 ASP B CG 1 ATOM 6638 O OD1 . ASP B 1 385 ? 182.531 63.098 -94.922 1.00 31.19 ? 393 ASP B OD1 1 ATOM 6639 O OD2 . ASP B 1 385 ? 184.455 62.288 -95.614 1.00 29.93 ? 393 ASP B OD2 1 ATOM 6640 N N . ILE B 1 386 ? 180.741 59.905 -93.807 1.00 23.78 ? 394 ILE B N 1 ATOM 6641 C CA . ILE B 1 386 ? 180.154 58.766 -94.523 1.00 24.03 ? 394 ILE B CA 1 ATOM 6642 C C . ILE B 1 386 ? 180.329 58.890 -96.040 1.00 26.35 ? 394 ILE B C 1 ATOM 6643 O O . ILE B 1 386 ? 179.931 59.897 -96.639 1.00 25.99 ? 394 ILE B O 1 ATOM 6644 C CB . ILE B 1 386 ? 178.643 58.627 -94.210 1.00 22.27 ? 394 ILE B CB 1 ATOM 6645 C CG1 . ILE B 1 386 ? 178.448 58.325 -92.724 1.00 21.00 ? 394 ILE B CG1 1 ATOM 6646 C CG2 . ILE B 1 386 ? 178.028 57.507 -95.038 1.00 19.76 ? 394 ILE B CG2 1 ATOM 6647 C CD1 . ILE B 1 386 ? 177.010 58.404 -92.261 1.00 21.05 ? 394 ILE B CD1 1 ATOM 6648 N N . LYS B 1 387 ? 180.918 57.853 -96.648 1.00 28.71 ? 395 LYS B N 1 ATOM 6649 C CA . LYS B 1 387 ? 181.172 57.804 -98.093 1.00 28.68 ? 395 LYS B CA 1 ATOM 6650 C C . LYS B 1 387 ? 180.149 56.944 -98.833 1.00 29.49 ? 395 LYS B C 1 ATOM 6651 O O . LYS B 1 387 ? 179.374 57.436 -99.647 1.00 29.03 ? 395 LYS B O 1 ATOM 6652 C CB . LYS B 1 387 ? 182.561 57.222 -98.371 1.00 27.39 ? 395 LYS B CB 1 ATOM 6653 C CG . LYS B 1 387 ? 183.717 57.905 -97.668 1.00 29.27 ? 395 LYS B CG 1 ATOM 6654 C CD . LYS B 1 387 ? 183.999 59.277 -98.248 1.00 33.29 ? 395 LYS B CD 1 ATOM 6655 C CE . LYS B 1 387 ? 185.268 59.882 -97.652 1.00 34.94 ? 395 LYS B CE 1 ATOM 6656 N NZ . LYS B 1 387 ? 185.557 61.219 -98.242 1.00 37.14 ? 395 LYS B NZ 1 ATOM 6657 N N . ASN B 1 388 ? 180.182 55.646 -98.544 1.00 32.87 ? 396 ASN B N 1 ATOM 6658 C CA . ASN B 1 388 ? 179.317 54.649 -99.172 1.00 34.38 ? 396 ASN B CA 1 ATOM 6659 C C . ASN B 1 388 ? 178.437 54.008 -98.109 1.00 34.00 ? 396 ASN B C 1 ATOM 6660 O O . ASN B 1 388 ? 178.378 54.464 -96.970 1.00 34.67 ? 396 ASN B O 1 ATOM 6661 C CB . ASN B 1 388 ? 180.167 53.532 -99.803 1.00 35.67 ? 396 ASN B CB 1 ATOM 6662 C CG . ASN B 1 388 ? 181.180 54.052 -100.802 1.00 40.52 ? 396 ASN B CG 1 ATOM 6663 O OD1 . ASN B 1 388 ? 180.869 54.264 -101.980 1.00 45.10 ? 396 ASN B OD1 1 ATOM 6664 N ND2 . ASN B 1 388 ? 182.394 54.304 -100.319 1.00 43.05 ? 396 ASN B ND2 1 ATOM 6665 N N . ARG B 1 389 ? 177.767 52.931 -98.502 1.00 33.24 ? 397 ARG B N 1 ATOM 6666 C CA . ARG B 1 389 ? 176.919 52.161 -97.609 1.00 31.00 ? 397 ARG B CA 1 ATOM 6667 C C . ARG B 1 389 ? 177.884 51.213 -96.913 1.00 30.65 ? 397 ARG B C 1 ATOM 6668 O O . ARG B 1 389 ? 177.534 50.562 -95.936 1.00 31.21 ? 397 ARG B O 1 ATOM 6669 C CB . ARG B 1 389 ? 175.929 51.313 -98.404 1.00 30.84 ? 397 ARG B CB 1 ATOM 6670 C CG . ARG B 1 389 ? 176.607 50.115 -99.071 1.00 30.50 ? 397 ARG B CG 1 ATOM 6671 C CD . ARG B 1 389 ? 175.664 49.307 -99.942 1.00 31.66 ? 397 ARG B CD 1 ATOM 6672 N NE . ARG B 1 389 ? 175.160 50.091 -101.065 1.00 33.71 ? 397 ARG B NE 1 ATOM 6673 C CZ . ARG B 1 389 ? 174.363 49.612 -102.014 1.00 32.97 ? 397 ARG B CZ 1 ATOM 6674 N NH1 . ARG B 1 389 ? 173.974 48.346 -101.984 1.00 33.51 ? 397 ARG B NH1 1 ATOM 6675 N NH2 . ARG B 1 389 ? 173.943 50.407 -102.987 1.00 33.16 ? 397 ARG B NH2 1 ATOM 6676 N N . THR B 1 390 ? 179.100 51.115 -97.439 1.00 29.49 ? 398 THR B N 1 ATOM 6677 C CA . THR B 1 390 ? 180.076 50.219 -96.841 1.00 29.11 ? 398 THR B CA 1 ATOM 6678 C C . THR B 1 390 ? 181.198 50.946 -96.101 1.00 29.12 ? 398 THR B C 1 ATOM 6679 O O . THR B 1 390 ? 181.742 50.421 -95.125 1.00 29.99 ? 398 THR B O 1 ATOM 6680 C CB . THR B 1 390 ? 180.718 49.277 -97.908 1.00 27.50 ? 398 THR B CB 1 ATOM 6681 O OG1 . THR B 1 390 ? 181.460 50.048 -98.861 1.00 25.57 ? 398 THR B OG1 1 ATOM 6682 C CG2 . THR B 1 390 ? 179.647 48.488 -98.633 1.00 22.98 ? 398 THR B CG2 1 ATOM 6683 N N . HIS B 1 391 ? 181.529 52.155 -96.543 1.00 29.36 ? 399 HIS B N 1 ATOM 6684 C CA . HIS B 1 391 ? 182.625 52.901 -95.927 1.00 29.85 ? 399 HIS B CA 1 ATOM 6685 C C . HIS B 1 391 ? 182.291 54.229 -95.262 1.00 29.05 ? 399 HIS B C 1 ATOM 6686 O O . HIS B 1 391 ? 181.522 55.037 -95.788 1.00 30.33 ? 399 HIS B O 1 ATOM 6687 C CB . HIS B 1 391 ? 183.726 53.163 -96.962 1.00 30.06 ? 399 HIS B CB 1 ATOM 6688 C CG . HIS B 1 391 ? 184.475 51.938 -97.379 1.00 30.07 ? 399 HIS B CG 1 ATOM 6689 N ND1 . HIS B 1 391 ? 185.826 51.781 -97.152 1.00 31.27 ? 399 HIS B ND1 1 ATOM 6690 C CD2 . HIS B 1 391 ? 184.064 50.814 -98.009 1.00 29.67 ? 399 HIS B CD2 1 ATOM 6691 C CE1 . HIS B 1 391 ? 186.217 50.611 -97.625 1.00 31.80 ? 399 HIS B CE1 1 ATOM 6692 N NE2 . HIS B 1 391 ? 185.166 50.004 -98.149 1.00 32.48 ? 399 HIS B NE2 1 ATOM 6693 N N . ALA B 1 392 ? 182.908 54.448 -94.108 1.00 27.16 ? 400 ALA B N 1 ATOM 6694 C CA . ALA B 1 392 ? 182.754 55.684 -93.353 1.00 26.74 ? 400 ALA B CA 1 ATOM 6695 C C . ALA B 1 392 ? 184.129 55.964 -92.770 1.00 25.56 ? 400 ALA B C 1 ATOM 6696 O O . ALA B 1 392 ? 184.801 55.050 -92.283 1.00 23.69 ? 400 ALA B O 1 ATOM 6697 C CB . ALA B 1 392 ? 181.729 55.519 -92.242 1.00 25.60 ? 400 ALA B CB 1 ATOM 6698 N N . HIS B 1 393 ? 184.556 57.220 -92.838 1.00 25.51 ? 401 HIS B N 1 ATOM 6699 C CA . HIS B 1 393 ? 185.864 57.589 -92.330 1.00 26.86 ? 401 HIS B CA 1 ATOM 6700 C C . HIS B 1 393 ? 185.747 58.482 -91.112 1.00 26.20 ? 401 HIS B C 1 ATOM 6701 O O . HIS B 1 393 ? 185.131 59.548 -91.168 1.00 27.08 ? 401 HIS B O 1 ATOM 6702 C CB . HIS B 1 393 ? 186.670 58.308 -93.416 1.00 29.92 ? 401 HIS B CB 1 ATOM 6703 C CG . HIS B 1 393 ? 188.097 58.560 -93.040 1.00 35.73 ? 401 HIS B CG 1 ATOM 6704 N ND1 . HIS B 1 393 ? 188.712 59.782 -93.222 1.00 39.48 ? 401 HIS B ND1 1 ATOM 6705 C CD2 . HIS B 1 393 ? 189.034 57.746 -92.497 1.00 37.44 ? 401 HIS B CD2 1 ATOM 6706 C CE1 . HIS B 1 393 ? 189.965 59.709 -92.806 1.00 39.66 ? 401 HIS B CE1 1 ATOM 6707 N NE2 . HIS B 1 393 ? 190.186 58.484 -92.362 1.00 39.82 ? 401 HIS B NE2 1 ATOM 6708 N N . PHE B 1 394 ? 186.343 58.037 -90.012 1.00 25.01 ? 402 PHE B N 1 ATOM 6709 C CA . PHE B 1 394 ? 186.330 58.797 -88.772 1.00 24.28 ? 402 PHE B CA 1 ATOM 6710 C C . PHE B 1 394 ? 187.710 59.368 -88.519 1.00 24.69 ? 402 PHE B C 1 ATOM 6711 O O . PHE B 1 394 ? 188.719 58.722 -88.811 1.00 25.56 ? 402 PHE B O 1 ATOM 6712 C CB . PHE B 1 394 ? 185.951 57.918 -87.579 1.00 22.92 ? 402 PHE B CB 1 ATOM 6713 C CG . PHE B 1 394 ? 186.040 58.634 -86.262 1.00 22.92 ? 402 PHE B CG 1 ATOM 6714 C CD1 . PHE B 1 394 ? 185.100 59.596 -85.915 1.00 22.33 ? 402 PHE B CD1 1 ATOM 6715 C CD2 . PHE B 1 394 ? 187.103 58.396 -85.399 1.00 23.22 ? 402 PHE B CD2 1 ATOM 6716 C CE1 . PHE B 1 394 ? 185.220 60.315 -84.732 1.00 22.06 ? 402 PHE B CE1 1 ATOM 6717 C CE2 . PHE B 1 394 ? 187.233 59.108 -84.217 1.00 23.51 ? 402 PHE B CE2 1 ATOM 6718 C CZ . PHE B 1 394 ? 186.290 60.071 -83.883 1.00 23.91 ? 402 PHE B CZ 1 ATOM 6719 N N . SER B 1 395 ? 187.756 60.572 -87.962 1.00 24.55 ? 403 SER B N 1 ATOM 6720 C CA . SER B 1 395 ? 189.029 61.202 -87.663 1.00 24.70 ? 403 SER B CA 1 ATOM 6721 C C . SER B 1 395 ? 188.882 62.113 -86.468 1.00 25.36 ? 403 SER B C 1 ATOM 6722 O O . SER B 1 395 ? 187.825 62.716 -86.261 1.00 25.77 ? 403 SER B O 1 ATOM 6723 C CB . SER B 1 395 ? 189.527 62.000 -88.867 1.00 24.86 ? 403 SER B CB 1 ATOM 6724 O OG . SER B 1 395 ? 188.579 62.977 -89.248 1.00 28.01 ? 403 SER B OG 1 ATOM 6725 N N . TRP B 1 396 ? 189.960 62.204 -85.694 1.00 26.19 ? 404 TRP B N 1 ATOM 6726 C CA . TRP B 1 396 ? 190.022 63.021 -84.493 1.00 25.10 ? 404 TRP B CA 1 ATOM 6727 C C . TRP B 1 396 ? 191.056 64.129 -84.668 1.00 25.97 ? 404 TRP B C 1 ATOM 6728 O O . TRP B 1 396 ? 192.208 63.851 -85.001 1.00 26.43 ? 404 TRP B O 1 ATOM 6729 C CB . TRP B 1 396 ? 190.411 62.139 -83.314 1.00 25.25 ? 404 TRP B CB 1 ATOM 6730 C CG . TRP B 1 396 ? 190.564 62.882 -82.025 1.00 26.67 ? 404 TRP B CG 1 ATOM 6731 C CD1 . TRP B 1 396 ? 189.617 63.641 -81.399 1.00 24.98 ? 404 TRP B CD1 1 ATOM 6732 C CD2 . TRP B 1 396 ? 191.722 62.901 -81.176 1.00 26.20 ? 404 TRP B CD2 1 ATOM 6733 N NE1 . TRP B 1 396 ? 190.108 64.128 -80.213 1.00 26.08 ? 404 TRP B NE1 1 ATOM 6734 C CE2 . TRP B 1 396 ? 191.397 63.689 -80.049 1.00 26.58 ? 404 TRP B CE2 1 ATOM 6735 C CE3 . TRP B 1 396 ? 193.000 62.325 -81.257 1.00 25.40 ? 404 TRP B CE3 1 ATOM 6736 C CZ2 . TRP B 1 396 ? 192.306 63.917 -79.006 1.00 26.50 ? 404 TRP B CZ2 1 ATOM 6737 C CZ3 . TRP B 1 396 ? 193.905 62.548 -80.218 1.00 24.80 ? 404 TRP B CZ3 1 ATOM 6738 C CH2 . TRP B 1 396 ? 193.550 63.338 -79.109 1.00 27.00 ? 404 TRP B CH2 1 ATOM 6739 N N . ASN B 1 397 ? 190.648 65.379 -84.455 1.00 27.03 ? 405 ASN B N 1 ATOM 6740 C CA . ASN B 1 397 ? 191.562 66.516 -84.588 1.00 28.15 ? 405 ASN B CA 1 ATOM 6741 C C . ASN B 1 397 ? 191.840 67.172 -83.240 1.00 28.71 ? 405 ASN B C 1 ATOM 6742 O O . ASN B 1 397 ? 190.911 67.503 -82.494 1.00 28.31 ? 405 ASN B O 1 ATOM 6743 C CB . ASN B 1 397 ? 190.998 67.565 -85.558 1.00 29.41 ? 405 ASN B CB 1 ATOM 6744 C CG . ASN B 1 397 ? 191.763 68.892 -85.501 1.00 30.30 ? 405 ASN B CG 1 ATOM 6745 O OD1 . ASN B 1 397 ? 191.357 69.833 -84.808 1.00 30.20 ? 405 ASN B OD1 1 ATOM 6746 N ND2 . ASN B 1 397 ? 192.880 68.963 -86.221 1.00 29.19 ? 405 ASN B ND2 1 ATOM 6747 N N . ARG B 1 398 ? 193.125 67.362 -82.944 1.00 28.75 ? 406 ARG B N 1 ATOM 6748 C CA . ARG B 1 398 ? 193.557 67.966 -81.690 1.00 29.22 ? 406 ARG B CA 1 ATOM 6749 C C . ARG B 1 398 ? 193.672 69.481 -81.804 1.00 30.85 ? 406 ARG B C 1 ATOM 6750 O O . ARG B 1 398 ? 193.896 70.014 -82.887 1.00 33.24 ? 406 ARG B O 1 ATOM 6751 C CB . ARG B 1 398 ? 194.903 67.382 -81.265 1.00 27.01 ? 406 ARG B CB 1 ATOM 6752 C CG . ARG B 1 398 ? 194.907 65.870 -81.138 1.00 27.55 ? 406 ARG B CG 1 ATOM 6753 C CD . ARG B 1 398 ? 196.186 65.384 -80.497 1.00 27.44 ? 406 ARG B CD 1 ATOM 6754 N NE . ARG B 1 398 ? 197.364 65.904 -81.183 1.00 28.61 ? 406 ARG B NE 1 ATOM 6755 C CZ . ARG B 1 398 ? 198.605 65.803 -80.717 1.00 29.57 ? 406 ARG B CZ 1 ATOM 6756 N NH1 . ARG B 1 398 ? 198.839 65.197 -79.558 1.00 28.84 ? 406 ARG B NH1 1 ATOM 6757 N NH2 . ARG B 1 398 ? 199.613 66.322 -81.401 1.00 29.05 ? 406 ARG B NH2 1 ATOM 6758 N N . ASN B 1 399 ? 193.515 70.169 -80.679 1.00 31.34 ? 407 ASN B N 1 ATOM 6759 C CA . ASN B 1 399 ? 193.602 71.618 -80.657 1.00 31.35 ? 407 ASN B CA 1 ATOM 6760 C C . ASN B 1 399 ? 195.041 72.108 -80.821 1.00 31.68 ? 407 ASN B C 1 ATOM 6761 O O . ASN B 1 399 ? 195.252 73.225 -81.292 1.00 32.62 ? 407 ASN B O 1 ATOM 6762 C CB . ASN B 1 399 ? 192.997 72.160 -79.354 1.00 32.15 ? 407 ASN B CB 1 ATOM 6763 C CG . ASN B 1 399 ? 191.471 72.201 -79.386 1.00 31.48 ? 407 ASN B CG 1 ATOM 6764 O OD1 . ASN B 1 399 ? 190.833 71.505 -80.180 1.00 32.90 ? 407 ASN B OD1 1 ATOM 6765 N ND2 . ASN B 1 399 ? 190.882 73.013 -78.512 1.00 30.59 ? 407 ASN B ND2 1 ATOM 6766 N N . GLN B 1 400 ? 196.026 71.289 -80.445 1.00 31.86 ? 408 GLN B N 1 ATOM 6767 C CA . GLN B 1 400 ? 197.428 71.693 -80.590 1.00 32.90 ? 408 GLN B CA 1 ATOM 6768 C C . GLN B 1 400 ? 197.868 71.591 -82.043 1.00 34.03 ? 408 GLN B C 1 ATOM 6769 O O . GLN B 1 400 ? 198.729 72.350 -82.495 1.00 35.71 ? 408 GLN B O 1 ATOM 6770 C CB . GLN B 1 400 ? 198.386 70.809 -79.789 1.00 32.78 ? 408 GLN B CB 1 ATOM 6771 C CG . GLN B 1 400 ? 197.933 70.377 -78.425 1.00 37.75 ? 408 GLN B CG 1 ATOM 6772 C CD . GLN B 1 400 ? 197.222 69.045 -78.462 1.00 38.23 ? 408 GLN B CD 1 ATOM 6773 O OE1 . GLN B 1 400 ? 196.002 68.981 -78.644 1.00 38.75 ? 408 GLN B OE1 1 ATOM 6774 N NE2 . GLN B 1 400 ? 197.984 67.965 -78.308 1.00 35.89 ? 408 GLN B NE2 1 ATOM 6775 N N . ASP B 1 401 ? 197.297 70.636 -82.771 1.00 33.23 ? 409 ASP B N 1 ATOM 6776 C CA . ASP B 1 401 ? 197.676 70.444 -84.162 1.00 32.94 ? 409 ASP B CA 1 ATOM 6777 C C . ASP B 1 401 ? 197.003 71.426 -85.098 1.00 33.70 ? 409 ASP B C 1 ATOM 6778 O O . ASP B 1 401 ? 196.147 72.215 -84.689 1.00 33.89 ? 409 ASP B O 1 ATOM 6779 C CB . ASP B 1 401 ? 197.358 69.020 -84.612 1.00 32.59 ? 409 ASP B CB 1 ATOM 6780 C CG . ASP B 1 401 ? 197.973 67.986 -83.709 1.00 33.32 ? 409 ASP B CG 1 ATOM 6781 O OD1 . ASP B 1 401 ? 199.084 68.239 -83.193 1.00 33.79 ? 409 ASP B OD1 1 ATOM 6782 O OD2 . ASP B 1 401 ? 197.351 66.923 -83.520 1.00 34.62 ? 409 ASP B OD2 1 ATOM 6783 N N . GLY B 1 402 ? 197.415 71.377 -86.360 1.00 33.88 ? 410 GLY B N 1 ATOM 6784 C CA . GLY B 1 402 ? 196.841 72.251 -87.358 1.00 33.83 ? 410 GLY B CA 1 ATOM 6785 C C . GLY B 1 402 ? 195.425 71.821 -87.674 1.00 34.09 ? 410 GLY B C 1 ATOM 6786 O O . GLY B 1 402 ? 195.051 70.661 -87.467 1.00 33.98 ? 410 GLY B O 1 ATOM 6787 N N . VAL B 1 403 ? 194.642 72.764 -88.181 1.00 33.62 ? 411 VAL B N 1 ATOM 6788 C CA . VAL B 1 403 ? 193.255 72.527 -88.534 1.00 33.82 ? 411 VAL B CA 1 ATOM 6789 C C . VAL B 1 403 ? 193.034 71.282 -89.398 1.00 33.71 ? 411 VAL B C 1 ATOM 6790 O O . VAL B 1 403 ? 192.047 70.562 -89.212 1.00 33.49 ? 411 VAL B O 1 ATOM 6791 C CB . VAL B 1 403 ? 192.692 73.765 -89.250 1.00 34.59 ? 411 VAL B CB 1 ATOM 6792 C CG1 . VAL B 1 403 ? 191.320 73.474 -89.820 1.00 37.68 ? 411 VAL B CG1 1 ATOM 6793 C CG2 . VAL B 1 403 ? 192.623 74.924 -88.268 1.00 34.25 ? 411 VAL B CG2 1 ATOM 6794 N N . ALA B 1 404 ? 193.951 71.015 -90.326 1.00 33.30 ? 412 ALA B N 1 ATOM 6795 C CA . ALA B 1 404 ? 193.812 69.858 -91.215 1.00 33.80 ? 412 ALA B CA 1 ATOM 6796 C C . ALA B 1 404 ? 194.544 68.577 -90.788 1.00 33.68 ? 412 ALA B C 1 ATOM 6797 O O . ALA B 1 404 ? 194.558 67.594 -91.537 1.00 33.73 ? 412 ALA B O 1 ATOM 6798 C CB . ALA B 1 404 ? 194.238 70.243 -92.624 1.00 33.07 ? 412 ALA B CB 1 ATOM 6799 N N . VAL B 1 405 ? 195.134 68.574 -89.594 1.00 33.62 ? 413 VAL B N 1 ATOM 6800 C CA . VAL B 1 405 ? 195.868 67.402 -89.104 1.00 34.48 ? 413 VAL B CA 1 ATOM 6801 C C . VAL B 1 405 ? 194.964 66.422 -88.358 1.00 35.49 ? 413 VAL B C 1 ATOM 6802 O O . VAL B 1 405 ? 194.238 66.819 -87.446 1.00 36.71 ? 413 VAL B O 1 ATOM 6803 C CB . VAL B 1 405 ? 197.001 67.808 -88.127 1.00 34.27 ? 413 VAL B CB 1 ATOM 6804 C CG1 . VAL B 1 405 ? 197.840 66.589 -87.774 1.00 32.14 ? 413 VAL B CG1 1 ATOM 6805 C CG2 . VAL B 1 405 ? 197.865 68.899 -88.736 1.00 33.48 ? 413 VAL B CG2 1 ATOM 6806 N N . GLU B 1 406 ? 195.016 65.145 -88.728 1.00 34.75 ? 414 GLU B N 1 ATOM 6807 C CA . GLU B 1 406 ? 194.200 64.140 -88.057 1.00 33.86 ? 414 GLU B CA 1 ATOM 6808 C C . GLU B 1 406 ? 195.094 63.264 -87.194 1.00 32.78 ? 414 GLU B C 1 ATOM 6809 O O . GLU B 1 406 ? 195.777 62.380 -87.697 1.00 33.08 ? 414 GLU B O 1 ATOM 6810 C CB . GLU B 1 406 ? 193.477 63.255 -89.069 1.00 34.86 ? 414 GLU B CB 1 ATOM 6811 C CG . GLU B 1 406 ? 192.806 64.001 -90.198 1.00 39.34 ? 414 GLU B CG 1 ATOM 6812 C CD . GLU B 1 406 ? 192.137 63.056 -91.184 1.00 43.78 ? 414 GLU B CD 1 ATOM 6813 O OE1 . GLU B 1 406 ? 192.745 62.017 -91.529 1.00 44.63 ? 414 GLU B OE1 1 ATOM 6814 O OE2 . GLU B 1 406 ? 191.002 63.352 -91.618 1.00 48.11 ? 414 GLU B OE2 1 ATOM 6815 N N . ALA B 1 407 ? 195.082 63.506 -85.890 1.00 32.42 ? 415 ALA B N 1 ATOM 6816 C CA . ALA B 1 407 ? 195.898 62.730 -84.966 1.00 31.22 ? 415 ALA B CA 1 ATOM 6817 C C . ALA B 1 407 ? 195.428 61.282 -84.901 1.00 31.28 ? 415 ALA B C 1 ATOM 6818 O O . ALA B 1 407 ? 196.169 60.398 -84.479 1.00 31.43 ? 415 ALA B O 1 ATOM 6819 C CB . ALA B 1 407 ? 195.855 63.358 -83.585 1.00 32.43 ? 415 ALA B CB 1 ATOM 6820 N N . ASP B 1 408 ? 194.188 61.038 -85.302 1.00 30.85 ? 416 ASP B N 1 ATOM 6821 C CA . ASP B 1 408 ? 193.663 59.681 -85.304 1.00 31.75 ? 416 ASP B CA 1 ATOM 6822 C C . ASP B 1 408 ? 192.696 59.528 -86.467 1.00 32.98 ? 416 ASP B C 1 ATOM 6823 O O . ASP B 1 408 ? 191.739 60.286 -86.607 1.00 34.55 ? 416 ASP B O 1 ATOM 6824 C CB . ASP B 1 408 ? 192.970 59.349 -83.983 1.00 31.62 ? 416 ASP B CB 1 ATOM 6825 C CG . ASP B 1 408 ? 192.652 57.871 -83.856 1.00 31.39 ? 416 ASP B CG 1 ATOM 6826 O OD1 . ASP B 1 408 ? 193.548 57.063 -84.157 1.00 33.84 ? 416 ASP B OD1 1 ATOM 6827 O OD2 . ASP B 1 408 ? 191.522 57.507 -83.460 1.00 32.17 ? 416 ASP B OD2 1 ATOM 6828 N N . SER B 1 409 ? 192.973 58.545 -87.313 1.00 33.45 ? 417 SER B N 1 ATOM 6829 C CA . SER B 1 409 ? 192.171 58.285 -88.493 1.00 32.51 ? 417 SER B CA 1 ATOM 6830 C C . SER B 1 409 ? 191.810 56.813 -88.539 1.00 31.39 ? 417 SER B C 1 ATOM 6831 O O . SER B 1 409 ? 192.650 55.951 -88.293 1.00 32.27 ? 417 SER B O 1 ATOM 6832 C CB . SER B 1 409 ? 192.963 58.668 -89.742 1.00 33.08 ? 417 SER B CB 1 ATOM 6833 O OG . SER B 1 409 ? 192.307 58.230 -90.915 1.00 37.55 ? 417 SER B OG 1 ATOM 6834 N N . VAL B 1 410 ? 190.552 56.527 -88.842 1.00 29.49 ? 418 VAL B N 1 ATOM 6835 C CA . VAL B 1 410 ? 190.102 55.151 -88.907 1.00 28.54 ? 418 VAL B CA 1 ATOM 6836 C C . VAL B 1 410 ? 189.000 54.980 -89.930 1.00 28.10 ? 418 VAL B C 1 ATOM 6837 O O . VAL B 1 410 ? 188.123 55.832 -90.054 1.00 27.70 ? 418 VAL B O 1 ATOM 6838 C CB . VAL B 1 410 ? 189.554 54.670 -87.546 1.00 28.27 ? 418 VAL B CB 1 ATOM 6839 C CG1 . VAL B 1 410 ? 189.115 53.220 -87.648 1.00 28.41 ? 418 VAL B CG1 1 ATOM 6840 C CG2 . VAL B 1 410 ? 190.604 54.819 -86.484 1.00 30.44 ? 418 VAL B CG2 1 ATOM 6841 N N . TRP B 1 411 ? 189.055 53.879 -90.671 1.00 27.60 ? 419 TRP B N 1 ATOM 6842 C CA . TRP B 1 411 ? 188.020 53.584 -91.645 1.00 27.43 ? 419 TRP B CA 1 ATOM 6843 C C . TRP B 1 411 ? 187.079 52.586 -90.996 1.00 27.23 ? 419 TRP B C 1 ATOM 6844 O O . TRP B 1 411 ? 187.521 51.553 -90.483 1.00 27.39 ? 419 TRP B O 1 ATOM 6845 C CB . TRP B 1 411 ? 188.613 52.982 -92.922 1.00 28.14 ? 419 TRP B CB 1 ATOM 6846 C CG . TRP B 1 411 ? 189.093 54.024 -93.879 1.00 30.14 ? 419 TRP B CG 1 ATOM 6847 C CD1 . TRP B 1 411 ? 190.377 54.460 -94.051 1.00 29.41 ? 419 TRP B CD1 1 ATOM 6848 C CD2 . TRP B 1 411 ? 188.276 54.839 -94.729 1.00 30.10 ? 419 TRP B CD2 1 ATOM 6849 N NE1 . TRP B 1 411 ? 190.408 55.499 -94.951 1.00 30.36 ? 419 TRP B NE1 1 ATOM 6850 C CE2 . TRP B 1 411 ? 189.133 55.753 -95.383 1.00 29.75 ? 419 TRP B CE2 1 ATOM 6851 C CE3 . TRP B 1 411 ? 186.900 54.887 -94.998 1.00 30.20 ? 419 TRP B CE3 1 ATOM 6852 C CZ2 . TRP B 1 411 ? 188.659 56.710 -96.289 1.00 30.42 ? 419 TRP B CZ2 1 ATOM 6853 C CZ3 . TRP B 1 411 ? 186.425 55.840 -95.900 1.00 29.54 ? 419 TRP B CZ3 1 ATOM 6854 C CH2 . TRP B 1 411 ? 187.304 56.737 -96.534 1.00 31.22 ? 419 TRP B CH2 1 ATOM 6855 N N . PHE B 1 412 ? 185.790 52.912 -90.985 1.00 26.22 ? 420 PHE B N 1 ATOM 6856 C CA . PHE B 1 412 ? 184.782 52.025 -90.415 1.00 26.64 ? 420 PHE B CA 1 ATOM 6857 C C . PHE B 1 412 ? 184.151 51.217 -91.539 1.00 26.20 ? 420 PHE B C 1 ATOM 6858 O O . PHE B 1 412 ? 183.774 51.777 -92.577 1.00 24.65 ? 420 PHE B O 1 ATOM 6859 C CB . PHE B 1 412 ? 183.653 52.816 -89.731 1.00 26.75 ? 420 PHE B CB 1 ATOM 6860 C CG . PHE B 1 412 ? 183.980 53.299 -88.349 1.00 27.28 ? 420 PHE B CG 1 ATOM 6861 C CD1 . PHE B 1 412 ? 185.035 54.178 -88.131 1.00 27.20 ? 420 PHE B CD1 1 ATOM 6862 C CD2 . PHE B 1 412 ? 183.193 52.916 -87.269 1.00 27.59 ? 420 PHE B CD2 1 ATOM 6863 C CE1 . PHE B 1 412 ? 185.302 54.673 -86.860 1.00 27.67 ? 420 PHE B CE1 1 ATOM 6864 C CE2 . PHE B 1 412 ? 183.455 53.408 -85.989 1.00 28.11 ? 420 PHE B CE2 1 ATOM 6865 C CZ . PHE B 1 412 ? 184.511 54.289 -85.788 1.00 27.84 ? 420 PHE B CZ 1 ATOM 6866 N N . PHE B 1 413 ? 184.046 49.906 -91.349 1.00 26.21 ? 421 PHE B N 1 ATOM 6867 C CA . PHE B 1 413 ? 183.393 49.074 -92.350 1.00 26.17 ? 421 PHE B CA 1 ATOM 6868 C C . PHE B 1 413 ? 182.010 48.737 -91.797 1.00 26.85 ? 421 PHE B C 1 ATOM 6869 O O . PHE B 1 413 ? 181.882 48.159 -90.704 1.00 25.57 ? 421 PHE B O 1 ATOM 6870 C CB . PHE B 1 413 ? 184.205 47.811 -92.629 1.00 25.97 ? 421 PHE B CB 1 ATOM 6871 C CG . PHE B 1 413 ? 185.534 48.088 -93.263 1.00 29.51 ? 421 PHE B CG 1 ATOM 6872 C CD1 . PHE B 1 413 ? 185.704 49.199 -94.094 1.00 30.24 ? 421 PHE B CD1 1 ATOM 6873 C CD2 . PHE B 1 413 ? 186.619 47.248 -93.040 1.00 30.16 ? 421 PHE B CD2 1 ATOM 6874 C CE1 . PHE B 1 413 ? 186.938 49.470 -94.692 1.00 29.92 ? 421 PHE B CE1 1 ATOM 6875 C CE2 . PHE B 1 413 ? 187.859 47.510 -93.636 1.00 29.83 ? 421 PHE B CE2 1 ATOM 6876 C CZ . PHE B 1 413 ? 188.015 48.624 -94.461 1.00 30.03 ? 421 PHE B CZ 1 ATOM 6877 N N . ASN B 1 414 ? 180.978 49.130 -92.540 1.00 25.51 ? 422 ASN B N 1 ATOM 6878 C CA . ASN B 1 414 ? 179.612 48.896 -92.109 1.00 25.62 ? 422 ASN B CA 1 ATOM 6879 C C . ASN B 1 414 ? 179.383 47.456 -91.651 1.00 25.06 ? 422 ASN B C 1 ATOM 6880 O O . ASN B 1 414 ? 179.746 46.510 -92.341 1.00 25.58 ? 422 ASN B O 1 ATOM 6881 C CB . ASN B 1 414 ? 178.644 49.264 -93.233 1.00 25.03 ? 422 ASN B CB 1 ATOM 6882 C CG . ASN B 1 414 ? 177.199 49.197 -92.794 1.00 24.82 ? 422 ASN B CG 1 ATOM 6883 O OD1 . ASN B 1 414 ? 176.536 48.164 -92.940 1.00 23.42 ? 422 ASN B OD1 1 ATOM 6884 N ND2 . ASN B 1 414 ? 176.701 50.301 -92.233 1.00 24.32 ? 422 ASN B ND2 1 ATOM 6885 N N . ARG B 1 415 ? 178.779 47.301 -90.478 1.00 25.56 ? 423 ARG B N 1 ATOM 6886 C CA . ARG B 1 415 ? 178.512 45.982 -89.913 1.00 25.02 ? 423 ARG B CA 1 ATOM 6887 C C . ARG B 1 415 ? 177.469 45.197 -90.682 1.00 25.39 ? 423 ARG B C 1 ATOM 6888 O O . ARG B 1 415 ? 177.419 43.973 -90.588 1.00 25.44 ? 423 ARG B O 1 ATOM 6889 C CB . ARG B 1 415 ? 178.062 46.109 -88.456 1.00 23.18 ? 423 ARG B CB 1 ATOM 6890 C CG . ARG B 1 415 ? 179.151 46.549 -87.496 1.00 21.58 ? 423 ARG B CG 1 ATOM 6891 C CD . ARG B 1 415 ? 180.326 45.595 -87.533 1.00 21.21 ? 423 ARG B CD 1 ATOM 6892 N NE . ARG B 1 415 ? 181.336 46.013 -88.499 1.00 22.25 ? 423 ARG B NE 1 ATOM 6893 C CZ . ARG B 1 415 ? 182.429 45.310 -88.785 1.00 22.64 ? 423 ARG B CZ 1 ATOM 6894 N NH1 . ARG B 1 415 ? 182.646 44.148 -88.179 1.00 22.66 ? 423 ARG B NH1 1 ATOM 6895 N NH2 . ARG B 1 415 ? 183.314 45.773 -89.662 1.00 20.23 ? 423 ARG B NH2 1 ATOM 6896 N N . HIS B 1 416 ? 176.634 45.887 -91.447 1.00 25.66 ? 424 HIS B N 1 ATOM 6897 C CA . HIS B 1 416 ? 175.600 45.192 -92.196 1.00 26.60 ? 424 HIS B CA 1 ATOM 6898 C C . HIS B 1 416 ? 176.004 44.866 -93.626 1.00 26.91 ? 424 HIS B C 1 ATOM 6899 O O . HIS B 1 416 ? 175.784 43.749 -94.087 1.00 26.85 ? 424 HIS B O 1 ATOM 6900 C CB . HIS B 1 416 ? 174.310 46.012 -92.220 1.00 27.23 ? 424 HIS B CB 1 ATOM 6901 C CG . HIS B 1 416 ? 173.173 45.324 -92.913 1.00 29.82 ? 424 HIS B CG 1 ATOM 6902 N ND1 . HIS B 1 416 ? 172.426 44.332 -92.314 1.00 31.18 ? 424 HIS B ND1 1 ATOM 6903 C CD2 . HIS B 1 416 ? 172.679 45.461 -94.168 1.00 30.30 ? 424 HIS B CD2 1 ATOM 6904 C CE1 . HIS B 1 416 ? 171.522 43.888 -93.170 1.00 30.94 ? 424 HIS B CE1 1 ATOM 6905 N NE2 . HIS B 1 416 ? 171.654 44.556 -94.303 1.00 29.87 ? 424 HIS B NE2 1 ATOM 6906 N N . TRP B 1 417 ? 176.600 45.831 -94.319 1.00 27.48 ? 425 TRP B N 1 ATOM 6907 C CA . TRP B 1 417 ? 176.991 45.633 -95.715 1.00 28.78 ? 425 TRP B CA 1 ATOM 6908 C C . TRP B 1 417 ? 178.427 45.211 -96.009 1.00 29.43 ? 425 TRP B C 1 ATOM 6909 O O . TRP B 1 417 ? 178.685 44.581 -97.032 1.00 31.66 ? 425 TRP B O 1 ATOM 6910 C CB . TRP B 1 417 ? 176.699 46.898 -96.524 1.00 29.24 ? 425 TRP B CB 1 ATOM 6911 C CG . TRP B 1 417 ? 175.259 47.245 -96.591 1.00 28.67 ? 425 TRP B CG 1 ATOM 6912 C CD1 . TRP B 1 417 ? 174.573 48.057 -95.746 1.00 28.21 ? 425 TRP B CD1 1 ATOM 6913 C CD2 . TRP B 1 417 ? 174.310 46.762 -97.545 1.00 29.52 ? 425 TRP B CD2 1 ATOM 6914 N NE1 . TRP B 1 417 ? 173.250 48.114 -96.109 1.00 27.93 ? 425 TRP B NE1 1 ATOM 6915 C CE2 . TRP B 1 417 ? 173.062 47.326 -97.211 1.00 28.53 ? 425 TRP B CE2 1 ATOM 6916 C CE3 . TRP B 1 417 ? 174.393 45.902 -98.652 1.00 29.23 ? 425 TRP B CE3 1 ATOM 6917 C CZ2 . TRP B 1 417 ? 171.902 47.062 -97.946 1.00 30.34 ? 425 TRP B CZ2 1 ATOM 6918 C CZ3 . TRP B 1 417 ? 173.243 45.641 -99.382 1.00 28.57 ? 425 TRP B CZ3 1 ATOM 6919 C CH2 . TRP B 1 417 ? 172.013 46.218 -99.026 1.00 29.98 ? 425 TRP B CH2 1 ATOM 6920 N N . TYR B 1 418 ? 179.359 45.560 -95.131 1.00 29.34 ? 426 TYR B N 1 ATOM 6921 C CA . TYR B 1 418 ? 180.767 45.234 -95.339 1.00 28.86 ? 426 TYR B CA 1 ATOM 6922 C C . TYR B 1 418 ? 181.369 44.743 -94.022 1.00 28.26 ? 426 TYR B C 1 ATOM 6923 O O . TYR B 1 418 ? 182.308 45.341 -93.491 1.00 27.25 ? 426 TYR B O 1 ATOM 6924 C CB . TYR B 1 418 ? 181.497 46.494 -95.824 1.00 29.18 ? 426 TYR B CB 1 ATOM 6925 C CG . TYR B 1 418 ? 182.738 46.221 -96.633 1.00 30.75 ? 426 TYR B CG 1 ATOM 6926 C CD1 . TYR B 1 418 ? 182.655 45.581 -97.863 1.00 31.38 ? 426 TYR B CD1 1 ATOM 6927 C CD2 . TYR B 1 418 ? 183.999 46.589 -96.163 1.00 32.29 ? 426 TYR B CD2 1 ATOM 6928 C CE1 . TYR B 1 418 ? 183.794 45.308 -98.610 1.00 32.71 ? 426 TYR B CE1 1 ATOM 6929 C CE2 . TYR B 1 418 ? 185.149 46.321 -96.902 1.00 33.24 ? 426 TYR B CE2 1 ATOM 6930 C CZ . TYR B 1 418 ? 185.037 45.678 -98.124 1.00 34.35 ? 426 TYR B CZ 1 ATOM 6931 O OH . TYR B 1 418 ? 186.171 45.389 -98.854 1.00 37.80 ? 426 TYR B OH 1 ATOM 6932 N N . PRO B 1 419 ? 180.837 43.636 -93.483 1.00 28.95 ? 427 PRO B N 1 ATOM 6933 C CA . PRO B 1 419 ? 181.312 43.065 -92.218 1.00 29.82 ? 427 PRO B CA 1 ATOM 6934 C C . PRO B 1 419 ? 182.717 42.450 -92.198 1.00 30.95 ? 427 PRO B C 1 ATOM 6935 O O . PRO B 1 419 ? 182.890 41.295 -91.811 1.00 32.24 ? 427 PRO B O 1 ATOM 6936 C CB . PRO B 1 419 ? 180.218 42.051 -91.874 1.00 28.60 ? 427 PRO B CB 1 ATOM 6937 C CG . PRO B 1 419 ? 179.788 41.565 -93.212 1.00 27.72 ? 427 PRO B CG 1 ATOM 6938 C CD . PRO B 1 419 ? 179.718 42.842 -94.029 1.00 28.87 ? 427 PRO B CD 1 ATOM 6939 N N . VAL B 1 420 ? 183.723 43.222 -92.594 1.00 32.13 ? 428 VAL B N 1 ATOM 6940 C CA . VAL B 1 420 ? 185.092 42.719 -92.585 1.00 33.78 ? 428 VAL B CA 1 ATOM 6941 C C . VAL B 1 420 ? 185.836 43.424 -91.452 1.00 36.12 ? 428 VAL B C 1 ATOM 6942 O O . VAL B 1 420 ? 185.515 44.565 -91.115 1.00 36.41 ? 428 VAL B O 1 ATOM 6943 C CB . VAL B 1 420 ? 185.808 42.977 -93.938 1.00 32.54 ? 428 VAL B CB 1 ATOM 6944 C CG1 . VAL B 1 420 ? 184.785 43.242 -95.032 1.00 31.55 ? 428 VAL B CG1 1 ATOM 6945 C CG2 . VAL B 1 420 ? 186.781 44.132 -93.817 1.00 32.92 ? 428 VAL B CG2 1 ATOM 6946 N N . ASP B 1 421 ? 186.824 42.753 -90.867 1.00 38.52 ? 429 ASP B N 1 ATOM 6947 C CA . ASP B 1 421 ? 187.566 43.344 -89.763 1.00 40.75 ? 429 ASP B CA 1 ATOM 6948 C C . ASP B 1 421 ? 188.197 44.672 -90.134 1.00 41.02 ? 429 ASP B C 1 ATOM 6949 O O . ASP B 1 421 ? 188.965 44.754 -91.091 1.00 41.47 ? 429 ASP B O 1 ATOM 6950 C CB . ASP B 1 421 ? 188.651 42.392 -89.263 1.00 44.04 ? 429 ASP B CB 1 ATOM 6951 C CG . ASP B 1 421 ? 189.330 42.905 -87.998 1.00 47.69 ? 429 ASP B CG 1 ATOM 6952 O OD1 . ASP B 1 421 ? 189.981 43.967 -88.064 1.00 49.49 ? 429 ASP B OD1 1 ATOM 6953 O OD2 . ASP B 1 421 ? 189.206 42.255 -86.933 1.00 50.80 ? 429 ASP B OD2 1 ATOM 6954 N N . ASP B 1 422 ? 187.875 45.708 -89.365 1.00 40.99 ? 430 ASP B N 1 ATOM 6955 C CA . ASP B 1 422 ? 188.414 47.040 -89.608 1.00 41.86 ? 430 ASP B CA 1 ATOM 6956 C C . ASP B 1 422 ? 189.230 47.560 -88.421 1.00 44.16 ? 430 ASP B C 1 ATOM 6957 O O . ASP B 1 422 ? 189.185 48.751 -88.097 1.00 44.86 ? 430 ASP B O 1 ATOM 6958 C CB . ASP B 1 422 ? 187.275 48.013 -89.951 1.00 39.71 ? 430 ASP B CB 1 ATOM 6959 C CG . ASP B 1 422 ? 186.212 48.102 -88.859 1.00 38.19 ? 430 ASP B CG 1 ATOM 6960 O OD1 . ASP B 1 422 ? 186.149 47.209 -87.987 1.00 35.96 ? 430 ASP B OD1 1 ATOM 6961 O OD2 . ASP B 1 422 ? 185.423 49.071 -88.888 1.00 36.45 ? 430 ASP B OD2 1 ATOM 6962 N N . SER B 1 423 ? 189.987 46.661 -87.790 1.00 45.60 ? 431 SER B N 1 ATOM 6963 C CA . SER B 1 423 ? 190.824 47.007 -86.643 1.00 48.33 ? 431 SER B CA 1 ATOM 6964 C C . SER B 1 423 ? 192.034 47.860 -87.030 1.00 49.77 ? 431 SER B C 1 ATOM 6965 O O . SER B 1 423 ? 192.472 47.854 -88.183 1.00 48.89 ? 431 SER B O 1 ATOM 6966 C CB . SER B 1 423 ? 191.306 45.733 -85.936 1.00 49.12 ? 431 SER B CB 1 ATOM 6967 O OG . SER B 1 423 ? 190.219 44.983 -85.418 1.00 50.85 ? 431 SER B OG 1 ATOM 6968 N N . THR B 1 424 ? 192.568 48.580 -86.044 1.00 52.30 ? 432 THR B N 1 ATOM 6969 C CA . THR B 1 424 ? 193.721 49.461 -86.222 1.00 54.17 ? 432 THR B CA 1 ATOM 6970 C C . THR B 1 424 ? 194.658 49.346 -85.027 1.00 55.11 ? 432 THR B C 1 ATOM 6971 O O . THR B 1 424 ? 194.526 50.105 -84.062 1.00 55.54 ? 432 THR B O 1 ATOM 6972 C CB . THR B 1 424 ? 193.284 50.932 -86.313 1.00 55.24 ? 432 THR B CB 1 ATOM 6973 O OG1 . THR B 1 424 ? 192.342 51.090 -87.380 1.00 56.67 ? 432 THR B OG1 1 ATOM 6974 C CG2 . THR B 1 424 ? 194.490 51.839 -86.555 1.00 57.00 ? 432 THR B CG2 1 HETATM 6975 FE FE . FE C 2 . ? 155.322 40.497 -59.588 1.00 22.24 ? 433 FE A FE 1 HETATM 6976 ZN ZN . ZN D 3 . ? 157.584 42.346 -60.512 1.00 16.82 ? 434 ZN A ZN 1 HETATM 6977 S S . SO4 E 4 . ? 156.145 39.921 -64.505 1.00 73.03 ? 435 SO4 A S 1 HETATM 6978 O O1 . SO4 E 4 . ? 155.128 39.496 -63.523 1.00 72.91 ? 435 SO4 A O1 1 HETATM 6979 O O2 . SO4 E 4 . ? 155.541 40.853 -65.473 1.00 74.37 ? 435 SO4 A O2 1 HETATM 6980 O O3 . SO4 E 4 . ? 157.254 40.601 -63.813 1.00 73.44 ? 435 SO4 A O3 1 HETATM 6981 O O4 . SO4 E 4 . ? 156.667 38.744 -65.226 1.00 74.20 ? 435 SO4 A O4 1 HETATM 6982 S S . SO4 F 4 . ? 180.610 58.550 -55.888 1.00 112.02 ? 437 SO4 A S 1 HETATM 6983 O O1 . SO4 F 4 . ? 180.648 57.598 -57.016 1.00 110.88 ? 437 SO4 A O1 1 HETATM 6984 O O2 . SO4 F 4 . ? 180.780 59.925 -56.401 1.00 109.67 ? 437 SO4 A O2 1 HETATM 6985 O O3 . SO4 F 4 . ? 179.309 58.439 -55.197 1.00 110.87 ? 437 SO4 A O3 1 HETATM 6986 O O4 . SO4 F 4 . ? 181.698 58.230 -54.938 1.00 110.67 ? 437 SO4 A O4 1 HETATM 6987 C C1 . NDG G 5 . ? 135.326 50.729 -71.651 1.00 52.60 ? 450 NDG A C1 1 HETATM 6988 C C2 . NDG G 5 . ? 133.957 50.179 -71.239 1.00 54.17 ? 450 NDG A C2 1 HETATM 6989 C C3 . NDG G 5 . ? 133.927 48.647 -71.351 1.00 54.28 ? 450 NDG A C3 1 HETATM 6990 C C4 . NDG G 5 . ? 134.298 48.274 -72.798 1.00 53.37 ? 450 NDG A C4 1 HETATM 6991 C C5 . NDG G 5 . ? 135.708 48.812 -73.073 1.00 52.33 ? 450 NDG A C5 1 HETATM 6992 C C6 . NDG G 5 . ? 136.222 48.464 -74.456 1.00 52.01 ? 450 NDG A C6 1 HETATM 6993 C C7 . NDG G 5 . ? 133.873 51.842 -69.494 1.00 54.94 ? 450 NDG A C7 1 HETATM 6994 C C8 . NDG G 5 . ? 134.763 52.040 -68.276 1.00 54.52 ? 450 NDG A C8 1 HETATM 6995 O O . NDG G 5 . ? 135.722 50.254 -72.956 1.00 52.68 ? 450 NDG A O 1 HETATM 6996 O O3 . NDG G 5 . ? 132.628 48.163 -71.010 1.00 54.58 ? 450 NDG A O3 1 HETATM 6997 O O4 . NDG G 5 . ? 134.268 46.860 -72.991 1.00 54.13 ? 450 NDG A O4 1 HETATM 6998 O O6 . NDG G 5 . ? 137.370 49.239 -74.774 1.00 50.82 ? 450 NDG A O6 1 HETATM 6999 O O7 . NDG G 5 . ? 133.405 52.825 -70.079 1.00 54.51 ? 450 NDG A O7 1 HETATM 7000 N N2 . NDG G 5 . ? 133.646 50.589 -69.884 1.00 54.96 ? 450 NDG A N2 1 HETATM 7001 O O1L . NDG G 5 . ? 136.287 50.352 -70.734 1.00 54.06 ? 450 NDG A O1L 1 HETATM 7002 C C1 . NAG H 6 . ? 139.186 34.729 -48.189 1.00 32.71 ? 451 NAG A C1 1 HETATM 7003 C C2 . NAG H 6 . ? 137.916 33.956 -48.543 1.00 33.91 ? 451 NAG A C2 1 HETATM 7004 C C3 . NAG H 6 . ? 136.869 34.143 -47.436 1.00 37.09 ? 451 NAG A C3 1 HETATM 7005 C C4 . NAG H 6 . ? 137.441 33.810 -46.051 1.00 37.68 ? 451 NAG A C4 1 HETATM 7006 C C5 . NAG H 6 . ? 138.773 34.541 -45.821 1.00 36.93 ? 451 NAG A C5 1 HETATM 7007 C C6 . NAG H 6 . ? 139.449 34.034 -44.562 1.00 37.61 ? 451 NAG A C6 1 HETATM 7008 C C7 . NAG H 6 . ? 137.718 33.858 -50.949 1.00 31.15 ? 451 NAG A C7 1 HETATM 7009 C C8 . NAG H 6 . ? 137.058 34.402 -52.207 1.00 31.80 ? 451 NAG A C8 1 HETATM 7010 N N2 . NAG H 6 . ? 137.376 34.433 -49.800 1.00 31.83 ? 451 NAG A N2 1 HETATM 7011 O O3 . NAG H 6 . ? 135.751 33.302 -47.691 1.00 40.22 ? 451 NAG A O3 1 HETATM 7012 O O4 . NAG H 6 . ? 136.504 34.193 -45.043 1.00 37.65 ? 451 NAG A O4 1 HETATM 7013 O O5 . NAG H 6 . ? 139.686 34.288 -46.914 1.00 35.07 ? 451 NAG A O5 1 HETATM 7014 O O6 . NAG H 6 . ? 140.571 34.836 -44.215 1.00 42.35 ? 451 NAG A O6 1 HETATM 7015 O O7 . NAG H 6 . ? 138.526 32.937 -51.031 1.00 30.26 ? 451 NAG A O7 1 HETATM 7016 C C1 . NAG I 6 . ? 168.988 38.596 -27.933 1.00 43.17 ? 452 NAG A C1 1 HETATM 7017 C C2 . NAG I 6 . ? 169.535 38.626 -26.504 1.00 44.52 ? 452 NAG A C2 1 HETATM 7018 C C3 . NAG I 6 . ? 170.065 37.219 -26.209 1.00 45.10 ? 452 NAG A C3 1 HETATM 7019 C C4 . NAG I 6 . ? 168.920 36.191 -26.371 1.00 45.74 ? 452 NAG A C4 1 HETATM 7020 C C5 . NAG I 6 . ? 168.242 36.343 -27.755 1.00 45.32 ? 452 NAG A C5 1 HETATM 7021 C C6 . NAG I 6 . ? 166.984 35.513 -27.890 1.00 47.26 ? 452 NAG A C6 1 HETATM 7022 C C7 . NAG I 6 . ? 170.417 40.655 -25.558 1.00 49.69 ? 452 NAG A C7 1 HETATM 7023 C C8 . NAG I 6 . ? 170.962 41.995 -26.042 1.00 49.94 ? 452 NAG A C8 1 HETATM 7024 N N2 . NAG I 6 . ? 170.594 39.603 -26.356 1.00 47.54 ? 452 NAG A N2 1 HETATM 7025 O O3 . NAG I 6 . ? 170.619 37.163 -24.894 1.00 43.64 ? 452 NAG A O3 1 HETATM 7026 O O4 . NAG I 6 . ? 169.427 34.860 -26.228 1.00 45.76 ? 452 NAG A O4 1 HETATM 7027 O O5 . NAG I 6 . ? 167.863 37.718 -27.996 1.00 42.18 ? 452 NAG A O5 1 HETATM 7028 O O6 . NAG I 6 . ? 165.865 36.323 -28.228 1.00 46.71 ? 452 NAG A O6 1 HETATM 7029 O O7 . NAG I 6 . ? 169.830 40.586 -24.471 1.00 48.15 ? 452 NAG A O7 1 HETATM 7030 C C1 . NDG J 5 . ? 126.317 64.292 -46.874 1.00 81.06 ? 453 NDG A C1 1 HETATM 7031 C C2 . NDG J 5 . ? 124.903 64.869 -46.757 1.00 80.90 ? 453 NDG A C2 1 HETATM 7032 C C3 . NDG J 5 . ? 124.768 66.160 -47.594 1.00 80.09 ? 453 NDG A C3 1 HETATM 7033 C C4 . NDG J 5 . ? 125.923 67.141 -47.315 1.00 78.69 ? 453 NDG A C4 1 HETATM 7034 C C5 . NDG J 5 . ? 127.291 66.431 -47.394 1.00 77.95 ? 453 NDG A C5 1 HETATM 7035 C C6 . NDG J 5 . ? 128.444 67.321 -46.964 1.00 75.61 ? 453 NDG A C6 1 HETATM 7036 C C7 . NDG J 5 . ? 123.482 62.953 -46.380 1.00 80.23 ? 453 NDG A C7 1 HETATM 7037 C C8 . NDG J 5 . ? 122.053 63.109 -45.879 1.00 80.81 ? 453 NDG A C8 1 HETATM 7038 O O . NDG J 5 . ? 127.313 65.274 -46.531 1.00 79.55 ? 453 NDG A O 1 HETATM 7039 O O3 . NDG J 5 . ? 123.533 66.800 -47.278 1.00 79.73 ? 453 NDG A O3 1 HETATM 7040 O O4 . NDG J 5 . ? 125.881 68.198 -48.270 1.00 77.78 ? 453 NDG A O4 1 HETATM 7041 O O6 . NDG J 5 . ? 129.526 66.548 -46.467 1.00 71.82 ? 453 NDG A O6 1 HETATM 7042 O O7 . NDG J 5 . ? 124.157 61.994 -46.000 1.00 79.55 ? 453 NDG A O7 1 HETATM 7043 N N2 . NDG J 5 . ? 123.945 63.879 -47.217 1.00 80.27 ? 453 NDG A N2 1 HETATM 7044 O O1L . NDG J 5 . ? 126.551 63.860 -48.168 1.00 82.13 ? 453 NDG A O1L 1 HETATM 7045 FE FE . FE K 2 . ? 181.625 66.724 -68.897 1.00 27.52 ? 433 FE B FE 1 HETATM 7046 ZN ZN . ZN L 3 . ? 179.622 64.483 -68.008 1.00 20.44 ? 434 ZN B ZN 1 HETATM 7047 S S . SO4 M 4 . ? 182.135 66.002 -64.267 1.00 71.46 ? 435 SO4 B S 1 HETATM 7048 O O1 . SO4 M 4 . ? 182.027 65.370 -62.932 1.00 69.81 ? 435 SO4 B O1 1 HETATM 7049 O O2 . SO4 M 4 . ? 180.827 65.955 -64.942 1.00 70.45 ? 435 SO4 B O2 1 HETATM 7050 O O3 . SO4 M 4 . ? 182.560 67.409 -64.125 1.00 71.81 ? 435 SO4 B O3 1 HETATM 7051 O O4 . SO4 M 4 . ? 183.128 65.279 -65.085 1.00 71.78 ? 435 SO4 B O4 1 HETATM 7052 S S . SO4 N 4 . ? 162.152 41.914 -72.276 1.00 103.66 ? 437 SO4 B S 1 HETATM 7053 O O1 . SO4 N 4 . ? 162.130 43.282 -71.723 1.00 102.63 ? 437 SO4 B O1 1 HETATM 7054 O O2 . SO4 N 4 . ? 163.029 41.877 -73.466 1.00 102.44 ? 437 SO4 B O2 1 HETATM 7055 O O3 . SO4 N 4 . ? 162.666 40.975 -71.258 1.00 102.00 ? 437 SO4 B O3 1 HETATM 7056 O O4 . SO4 N 4 . ? 160.778 41.524 -72.655 1.00 102.60 ? 437 SO4 B O4 1 HETATM 7057 C C1 . NAG O 6 . ? 171.002 85.842 -56.759 1.00 40.31 ? 450 NAG B C1 1 HETATM 7058 C C2 . NAG O 6 . ? 171.735 87.188 -56.893 1.00 41.80 ? 450 NAG B C2 1 HETATM 7059 C C3 . NAG O 6 . ? 173.167 87.091 -56.338 1.00 43.05 ? 450 NAG B C3 1 HETATM 7060 C C4 . NAG O 6 . ? 173.117 86.578 -54.894 1.00 43.68 ? 450 NAG B C4 1 HETATM 7061 C C5 . NAG O 6 . ? 172.380 85.229 -54.876 1.00 43.84 ? 450 NAG B C5 1 HETATM 7062 C C6 . NAG O 6 . ? 172.249 84.657 -53.473 1.00 44.82 ? 450 NAG B C6 1 HETATM 7063 C C7 . NAG O 6 . ? 170.814 88.390 -58.763 1.00 43.87 ? 450 NAG B C7 1 HETATM 7064 C C8 . NAG O 6 . ? 171.260 89.501 -59.706 1.00 45.16 ? 450 NAG B C8 1 HETATM 7065 N N2 . NAG O 6 . ? 171.760 87.584 -58.287 1.00 43.23 ? 450 NAG B N2 1 HETATM 7066 O O3 . NAG O 6 . ? 173.789 88.371 -56.366 1.00 43.17 ? 450 NAG B O3 1 HETATM 7067 O O4 . NAG O 6 . ? 174.441 86.438 -54.373 1.00 44.51 ? 450 NAG B O4 1 HETATM 7068 O O5 . NAG O 6 . ? 171.036 85.390 -55.394 1.00 42.49 ? 450 NAG B O5 1 HETATM 7069 O O6 . NAG O 6 . ? 173.411 83.936 -53.100 1.00 46.96 ? 450 NAG B O6 1 HETATM 7070 O O7 . NAG O 6 . ? 169.621 88.284 -58.461 1.00 41.84 ? 450 NAG B O7 1 HETATM 7071 C C1 . NAG P 6 . ? 187.210 82.824 -80.296 1.00 33.32 ? 451 NAG B C1 1 HETATM 7072 C C2 . NAG P 6 . ? 187.962 84.111 -79.944 1.00 34.31 ? 451 NAG B C2 1 HETATM 7073 C C3 . NAG P 6 . ? 187.742 85.174 -81.029 1.00 36.25 ? 451 NAG B C3 1 HETATM 7074 C C4 . NAG P 6 . ? 188.029 84.616 -82.427 1.00 37.06 ? 451 NAG B C4 1 HETATM 7075 C C5 . NAG P 6 . ? 187.242 83.324 -82.635 1.00 37.76 ? 451 NAG B C5 1 HETATM 7076 C C6 . NAG P 6 . ? 187.567 82.673 -83.956 1.00 39.49 ? 451 NAG B C6 1 HETATM 7077 C C7 . NAG P 6 . ? 188.144 84.341 -77.556 1.00 31.95 ? 451 NAG B C7 1 HETATM 7078 C C8 . NAG P 6 . ? 187.690 85.042 -76.285 1.00 31.64 ? 451 NAG B C8 1 HETATM 7079 N N2 . NAG P 6 . ? 187.488 84.623 -78.675 1.00 32.67 ? 451 NAG B N2 1 HETATM 7080 O O3 . NAG P 6 . ? 188.605 86.275 -80.786 1.00 38.97 ? 451 NAG B O3 1 HETATM 7081 O O4 . NAG P 6 . ? 187.654 85.579 -83.411 1.00 38.87 ? 451 NAG B O4 1 HETATM 7082 O O5 . NAG P 6 . ? 187.580 82.375 -81.607 1.00 35.44 ? 451 NAG B O5 1 HETATM 7083 O O6 . NAG P 6 . ? 188.940 82.315 -84.011 1.00 43.88 ? 451 NAG B O6 1 HETATM 7084 O O7 . NAG P 6 . ? 189.083 83.548 -77.515 1.00 32.37 ? 451 NAG B O7 1 HETATM 7085 C C1 . NAG Q 6 . ? 183.565 53.490 -100.623 1.00 44.78 ? 452 NAG B C1 1 HETATM 7086 C C2 . NAG Q 6 . ? 183.482 52.789 -101.996 1.00 46.26 ? 452 NAG B C2 1 HETATM 7087 C C3 . NAG Q 6 . ? 184.775 51.978 -102.217 1.00 47.77 ? 452 NAG B C3 1 HETATM 7088 C C4 . NAG Q 6 . ? 185.989 52.915 -102.122 1.00 49.05 ? 452 NAG B C4 1 HETATM 7089 C C5 . NAG Q 6 . ? 185.969 53.600 -100.749 1.00 49.47 ? 452 NAG B C5 1 HETATM 7090 C C6 . NAG Q 6 . ? 187.087 54.609 -100.572 1.00 51.31 ? 452 NAG B C6 1 HETATM 7091 C C7 . NAG Q 6 . ? 181.891 51.442 -103.205 1.00 48.47 ? 452 NAG B C7 1 HETATM 7092 C C8 . NAG Q 6 . ? 182.084 49.953 -103.463 1.00 49.04 ? 452 NAG B C8 1 HETATM 7093 N N2 . NAG Q 6 . ? 182.327 51.915 -102.041 1.00 47.28 ? 452 NAG B N2 1 HETATM 7094 O O3 . NAG Q 6 . ? 184.755 51.314 -103.478 1.00 47.49 ? 452 NAG B O3 1 HETATM 7095 O O4 . NAG Q 6 . ? 187.200 52.179 -102.285 1.00 50.02 ? 452 NAG B O4 1 HETATM 7096 O O5 . NAG Q 6 . ? 184.733 54.324 -100.568 1.00 46.23 ? 452 NAG B O5 1 HETATM 7097 O O6 . NAG Q 6 . ? 186.563 55.891 -100.242 1.00 50.57 ? 452 NAG B O6 1 HETATM 7098 O O7 . NAG Q 6 . ? 181.353 52.152 -104.063 1.00 47.05 ? 452 NAG B O7 1 HETATM 7099 C C1 . NAG R 6 . ? 158.195 95.083 -81.469 1.00 61.18 ? 453 NAG B C1 1 HETATM 7100 C C2 . NAG R 6 . ? 157.669 96.525 -81.658 1.00 63.82 ? 453 NAG B C2 1 HETATM 7101 C C3 . NAG R 6 . ? 156.354 96.764 -80.877 1.00 65.20 ? 453 NAG B C3 1 HETATM 7102 C C4 . NAG R 6 . ? 155.346 95.617 -81.071 1.00 64.92 ? 453 NAG B C4 1 HETATM 7103 C C5 . NAG R 6 . ? 156.039 94.256 -80.869 1.00 64.40 ? 453 NAG B C5 1 HETATM 7104 C C6 . NAG R 6 . ? 155.143 93.046 -81.092 1.00 63.40 ? 453 NAG B C6 1 HETATM 7105 C C7 . NAG R 6 . ? 159.311 98.256 -82.073 1.00 64.50 ? 453 NAG B C7 1 HETATM 7106 C C8 . NAG R 6 . ? 160.639 97.768 -82.632 1.00 64.45 ? 453 NAG B C8 1 HETATM 7107 N N2 . NAG R 6 . ? 158.674 97.472 -81.204 1.00 64.02 ? 453 NAG B N2 1 HETATM 7108 O O3 . NAG R 6 . ? 155.753 97.977 -81.324 1.00 66.42 ? 453 NAG B O3 1 HETATM 7109 O O4 . NAG R 6 . ? 154.291 95.771 -80.121 1.00 65.57 ? 453 NAG B O4 1 HETATM 7110 O O5 . NAG R 6 . ? 157.159 94.132 -81.765 1.00 62.20 ? 453 NAG B O5 1 HETATM 7111 O O6 . NAG R 6 . ? 154.383 93.169 -82.282 1.00 63.12 ? 453 NAG B O6 1 HETATM 7112 O O7 . NAG R 6 . ? 158.878 99.355 -82.419 1.00 66.49 ? 453 NAG B O7 1 HETATM 7113 O O . HOH S 7 . ? 156.565 40.399 -61.409 1.00 29.22 ? 454 HOH A O 1 HETATM 7114 O O . HOH S 7 . ? 175.841 56.550 -64.235 1.00 1.00 ? 455 HOH A O 1 HETATM 7115 O O . HOH S 7 . ? 138.059 65.667 -64.966 1.00 14.29 ? 456 HOH A O 1 HETATM 7116 O O . HOH S 7 . ? 171.973 41.153 -39.731 1.00 7.89 ? 457 HOH A O 1 HETATM 7117 O O . HOH S 7 . ? 163.415 44.350 -62.983 1.00 13.83 ? 458 HOH A O 1 HETATM 7118 O O . HOH S 7 . ? 163.121 58.768 -62.965 1.00 5.80 ? 459 HOH A O 1 HETATM 7119 O O . HOH S 7 . ? 155.524 26.813 -43.537 1.00 27.14 ? 460 HOH A O 1 HETATM 7120 O O . HOH S 7 . ? 169.326 32.696 -28.436 1.00 28.50 ? 461 HOH A O 1 HETATM 7121 O O . HOH S 7 . ? 161.361 49.386 -56.344 1.00 12.68 ? 462 HOH A O 1 HETATM 7122 O O . HOH S 7 . ? 150.168 52.300 -61.052 1.00 9.61 ? 463 HOH A O 1 HETATM 7123 O O . HOH S 7 . ? 159.637 52.019 -54.627 1.00 16.13 ? 464 HOH A O 1 HETATM 7124 O O . HOH S 7 . ? 168.810 46.442 -62.067 1.00 11.57 ? 465 HOH A O 1 HETATM 7125 O O . HOH S 7 . ? 176.754 39.334 -58.051 1.00 19.10 ? 466 HOH A O 1 HETATM 7126 O O . HOH S 7 . ? 183.760 40.901 -57.614 1.00 16.07 ? 467 HOH A O 1 HETATM 7127 O O . HOH S 7 . ? 160.087 51.292 -58.947 1.00 16.02 ? 468 HOH A O 1 HETATM 7128 O O . HOH S 7 . ? 160.594 59.384 -45.915 1.00 15.19 ? 469 HOH A O 1 HETATM 7129 O O . HOH S 7 . ? 133.975 68.989 -44.217 1.00 26.55 ? 470 HOH A O 1 HETATM 7130 O O . HOH S 7 . ? 166.279 59.618 -59.633 1.00 12.22 ? 471 HOH A O 1 HETATM 7131 O O . HOH S 7 . ? 142.579 49.439 -48.529 1.00 19.61 ? 472 HOH A O 1 HETATM 7132 O O . HOH S 7 . ? 136.616 48.595 -48.444 1.00 29.44 ? 473 HOH A O 1 HETATM 7133 O O . HOH S 7 . ? 168.050 42.896 -53.868 1.00 16.55 ? 474 HOH A O 1 HETATM 7134 O O . HOH S 7 . ? 176.134 42.346 -51.340 1.00 19.40 ? 475 HOH A O 1 HETATM 7135 O O . HOH S 7 . ? 173.844 39.020 -58.944 1.00 20.38 ? 476 HOH A O 1 HETATM 7136 O O . HOH S 7 . ? 166.152 46.771 -58.010 1.00 21.49 ? 477 HOH A O 1 HETATM 7137 O O . HOH S 7 . ? 153.285 36.796 -56.044 1.00 21.06 ? 478 HOH A O 1 HETATM 7138 O O . HOH S 7 . ? 168.892 55.888 -37.931 1.00 19.04 ? 479 HOH A O 1 HETATM 7139 O O . HOH S 7 . ? 164.300 60.785 -61.543 1.00 10.51 ? 480 HOH A O 1 HETATM 7140 O O . HOH S 7 . ? 187.915 40.052 -66.262 1.00 16.13 ? 481 HOH A O 1 HETATM 7141 O O . HOH S 7 . ? 185.048 38.282 -44.239 1.00 19.23 ? 482 HOH A O 1 HETATM 7142 O O . HOH S 7 . ? 155.524 37.390 -49.852 1.00 16.98 ? 483 HOH A O 1 HETATM 7143 O O . HOH S 7 . ? 166.495 48.015 -62.699 1.00 23.50 ? 484 HOH A O 1 HETATM 7144 O O . HOH S 7 . ? 143.656 51.081 -54.401 1.00 19.96 ? 485 HOH A O 1 HETATM 7145 O O . HOH S 7 . ? 183.118 41.338 -53.463 1.00 23.24 ? 486 HOH A O 1 HETATM 7146 O O . HOH S 7 . ? 150.467 55.420 -65.976 1.00 26.05 ? 487 HOH A O 1 HETATM 7147 O O . HOH S 7 . ? 141.213 51.346 -66.646 1.00 22.92 ? 488 HOH A O 1 HETATM 7148 O O . HOH S 7 . ? 171.084 32.999 -45.052 1.00 19.87 ? 489 HOH A O 1 HETATM 7149 O O . HOH S 7 . ? 153.721 34.024 -39.892 1.00 29.80 ? 490 HOH A O 1 HETATM 7150 O O . HOH S 7 . ? 158.887 54.033 -33.944 1.00 24.11 ? 491 HOH A O 1 HETATM 7151 O O . HOH S 7 . ? 139.081 40.857 -47.521 1.00 27.92 ? 492 HOH A O 1 HETATM 7152 O O . HOH S 7 . ? 172.225 36.746 -58.936 1.00 23.17 ? 493 HOH A O 1 HETATM 7153 O O . HOH S 7 . ? 147.819 63.733 -73.290 1.00 39.35 ? 494 HOH A O 1 HETATM 7154 O O . HOH S 7 . ? 183.929 39.201 -55.318 1.00 16.76 ? 495 HOH A O 1 HETATM 7155 O O . HOH S 7 . ? 176.015 55.252 -34.719 1.00 22.61 ? 496 HOH A O 1 HETATM 7156 O O . HOH S 7 . ? 160.850 30.817 -66.564 1.00 26.20 ? 497 HOH A O 1 HETATM 7157 O O . HOH S 7 . ? 131.659 61.768 -45.679 1.00 26.58 ? 498 HOH A O 1 HETATM 7158 O O . HOH S 7 . ? 178.630 61.648 -56.257 1.00 38.41 ? 499 HOH A O 1 HETATM 7159 O O . HOH S 7 . ? 149.714 46.514 -59.425 1.00 18.00 ? 500 HOH A O 1 HETATM 7160 O O . HOH S 7 . ? 145.870 61.708 -26.936 1.00 33.50 ? 501 HOH A O 1 HETATM 7161 O O . HOH S 7 . ? 190.767 48.004 -67.268 1.00 32.09 ? 502 HOH A O 1 HETATM 7162 O O . HOH S 7 . ? 158.652 37.946 -68.356 1.00 36.62 ? 503 HOH A O 1 HETATM 7163 O O . HOH S 7 . ? 154.322 49.546 -68.066 1.00 26.51 ? 504 HOH A O 1 HETATM 7164 O O . HOH S 7 . ? 145.834 39.214 -59.313 1.00 31.20 ? 505 HOH A O 1 HETATM 7165 O O . HOH S 7 . ? 137.595 58.825 -68.153 1.00 22.19 ? 506 HOH A O 1 HETATM 7166 O O . HOH S 7 . ? 152.991 48.492 -65.426 1.00 25.98 ? 507 HOH A O 1 HETATM 7167 O O . HOH S 7 . ? 166.839 40.722 -52.034 1.00 20.84 ? 508 HOH A O 1 HETATM 7168 O O . HOH S 7 . ? 137.722 54.702 -57.574 1.00 27.96 ? 509 HOH A O 1 HETATM 7169 O O . HOH S 7 . ? 149.519 57.808 -67.571 1.00 27.62 ? 510 HOH A O 1 HETATM 7170 O O . HOH S 7 . ? 152.560 59.540 -61.794 1.00 36.33 ? 511 HOH A O 1 HETATM 7171 O O . HOH S 7 . ? 151.312 32.097 -40.869 1.00 38.92 ? 512 HOH A O 1 HETATM 7172 O O . HOH S 7 . ? 165.049 52.305 -63.638 1.00 25.15 ? 513 HOH A O 1 HETATM 7173 O O . HOH S 7 . ? 165.153 63.017 -53.893 1.00 23.46 ? 514 HOH A O 1 HETATM 7174 O O . HOH S 7 . ? 191.942 37.219 -61.484 1.00 32.36 ? 515 HOH A O 1 HETATM 7175 O O . HOH S 7 . ? 178.187 48.511 -56.500 1.00 33.02 ? 516 HOH A O 1 HETATM 7176 O O . HOH S 7 . ? 158.955 63.462 -39.628 1.00 27.06 ? 517 HOH A O 1 HETATM 7177 O O . HOH S 7 . ? 148.597 52.851 -46.973 1.00 23.38 ? 518 HOH A O 1 HETATM 7178 O O . HOH S 7 . ? 171.263 40.471 -60.547 1.00 28.31 ? 519 HOH A O 1 HETATM 7179 O O . HOH S 7 . ? 134.768 60.768 -46.631 1.00 35.38 ? 520 HOH A O 1 HETATM 7180 O O . HOH S 7 . ? 163.729 23.788 -61.964 1.00 40.47 ? 521 HOH A O 1 HETATM 7181 O O . HOH S 7 . ? 131.676 54.901 -51.357 1.00 26.70 ? 522 HOH A O 1 HETATM 7182 O O . HOH S 7 . ? 133.050 34.848 -52.065 1.00 32.83 ? 523 HOH A O 1 HETATM 7183 O O . HOH S 7 . ? 156.175 31.814 -39.677 1.00 47.96 ? 524 HOH A O 1 HETATM 7184 O O . HOH S 7 . ? 180.513 43.231 -60.052 1.00 25.54 ? 525 HOH A O 1 HETATM 7185 O O . HOH S 7 . ? 145.723 40.246 -62.647 1.00 29.10 ? 526 HOH A O 1 HETATM 7186 O O . HOH S 7 . ? 160.688 24.094 -55.258 1.00 23.98 ? 527 HOH A O 1 HETATM 7187 O O . HOH S 7 . ? 132.245 50.895 -55.052 1.00 35.43 ? 528 HOH A O 1 HETATM 7188 O O . HOH S 7 . ? 148.595 49.414 -35.919 1.00 27.53 ? 529 HOH A O 1 HETATM 7189 O O . HOH S 7 . ? 123.654 69.366 -47.724 1.00 41.88 ? 530 HOH A O 1 HETATM 7190 O O . HOH S 7 . ? 176.595 42.223 -64.811 1.00 27.46 ? 531 HOH A O 1 HETATM 7191 O O . HOH S 7 . ? 159.621 40.866 -31.113 1.00 41.41 ? 532 HOH A O 1 HETATM 7192 O O . HOH S 7 . ? 148.644 47.698 -61.937 1.00 22.73 ? 533 HOH A O 1 HETATM 7193 O O . HOH S 7 . ? 152.388 58.993 -54.330 1.00 32.00 ? 534 HOH A O 1 HETATM 7194 O O . HOH S 7 . ? 150.567 47.330 -34.859 1.00 32.08 ? 535 HOH A O 1 HETATM 7195 O O . HOH S 7 . ? 178.962 45.669 -57.671 1.00 30.48 ? 536 HOH A O 1 HETATM 7196 O O . HOH S 7 . ? 152.566 49.167 -33.593 1.00 30.58 ? 537 HOH A O 1 HETATM 7197 O O . HOH S 7 . ? 162.738 36.528 -67.887 1.00 29.08 ? 538 HOH A O 1 HETATM 7198 O O . HOH S 7 . ? 174.747 27.627 -60.823 1.00 37.31 ? 539 HOH A O 1 HETATM 7199 O O . HOH S 7 . ? 145.969 63.591 -75.175 1.00 36.20 ? 540 HOH A O 1 HETATM 7200 O O . HOH S 7 . ? 167.944 40.023 -60.556 1.00 23.85 ? 541 HOH A O 1 HETATM 7201 O O . HOH S 7 . ? 144.762 48.954 -50.132 1.00 25.77 ? 542 HOH A O 1 HETATM 7202 O O . HOH S 7 . ? 154.818 59.799 -25.853 1.00 29.87 ? 543 HOH A O 1 HETATM 7203 O O . HOH S 7 . ? 152.332 26.829 -52.648 1.00 35.90 ? 544 HOH A O 1 HETATM 7204 O O . HOH S 7 . ? 160.893 57.960 -61.474 1.00 20.12 ? 545 HOH A O 1 HETATM 7205 O O . HOH S 7 . ? 159.530 61.987 -30.582 1.00 32.73 ? 546 HOH A O 1 HETATM 7206 O O . HOH S 7 . ? 149.145 48.443 -71.620 1.00 31.88 ? 547 HOH A O 1 HETATM 7207 O O . HOH S 7 . ? 132.580 45.739 -71.504 1.00 39.28 ? 548 HOH A O 1 HETATM 7208 O O . HOH S 7 . ? 140.078 68.915 -51.048 1.00 28.62 ? 549 HOH A O 1 HETATM 7209 O O . HOH S 7 . ? 168.343 33.085 -24.557 1.00 40.71 ? 550 HOH A O 1 HETATM 7210 O O . HOH S 7 . ? 159.883 56.018 -64.759 1.00 33.52 ? 551 HOH A O 1 HETATM 7211 O O . HOH S 7 . ? 129.292 62.024 -37.555 1.00 40.19 ? 552 HOH A O 1 HETATM 7212 O O . HOH S 7 . ? 168.174 54.014 -64.158 1.00 29.02 ? 553 HOH A O 1 HETATM 7213 O O . HOH S 7 . ? 178.124 54.573 -60.542 1.00 33.23 ? 554 HOH A O 1 HETATM 7214 O O . HOH S 7 . ? 159.347 30.411 -64.689 1.00 37.42 ? 555 HOH A O 1 HETATM 7215 O O . HOH S 7 . ? 161.119 33.224 -30.566 1.00 39.26 ? 556 HOH A O 1 HETATM 7216 O O . HOH S 7 . ? 136.802 45.537 -74.322 1.00 39.07 ? 557 HOH A O 1 HETATM 7217 O O . HOH S 7 . ? 161.846 31.255 -62.749 1.00 27.59 ? 558 HOH A O 1 HETATM 7218 O O . HOH S 7 . ? 170.158 34.039 -53.644 1.00 31.74 ? 559 HOH A O 1 HETATM 7219 O O . HOH S 7 . ? 182.531 49.375 -50.211 1.00 33.80 ? 560 HOH A O 1 HETATM 7220 O O . HOH S 7 . ? 185.935 37.142 -57.854 1.00 41.74 ? 561 HOH A O 1 HETATM 7221 O O . HOH S 7 . ? 178.010 50.088 -39.032 1.00 30.70 ? 562 HOH A O 1 HETATM 7222 O O . HOH S 7 . ? 143.754 62.433 -64.635 1.00 27.05 ? 563 HOH A O 1 HETATM 7223 O O . HOH S 7 . ? 145.175 27.695 -45.524 1.00 41.05 ? 564 HOH A O 1 HETATM 7224 O O . HOH S 7 . ? 132.284 48.172 -40.948 1.00 38.78 ? 565 HOH A O 1 HETATM 7225 O O . HOH S 7 . ? 134.267 33.604 -44.076 1.00 40.89 ? 566 HOH A O 1 HETATM 7226 O O . HOH S 7 . ? 160.069 35.303 -37.193 1.00 32.46 ? 567 HOH A O 1 HETATM 7227 O O . HOH S 7 . ? 171.437 35.781 -22.799 1.00 45.27 ? 568 HOH A O 1 HETATM 7228 O O . HOH S 7 . ? 158.419 48.226 -26.161 1.00 33.50 ? 569 HOH A O 1 HETATM 7229 O O . HOH S 7 . ? 152.842 60.375 -51.738 1.00 25.61 ? 570 HOH A O 1 HETATM 7230 O O . HOH S 7 . ? 175.966 56.015 -41.309 1.00 28.42 ? 571 HOH A O 1 HETATM 7231 O O . HOH S 7 . ? 130.199 65.903 -50.585 1.00 31.64 ? 572 HOH A O 1 HETATM 7232 O O . HOH S 7 . ? 141.086 60.060 -69.976 1.00 30.23 ? 573 HOH A O 1 HETATM 7233 O O . HOH S 7 . ? 146.915 42.505 -40.713 1.00 24.85 ? 574 HOH A O 1 HETATM 7234 O O . HOH S 7 . ? 151.455 51.619 -36.326 1.00 34.20 ? 575 HOH A O 1 HETATM 7235 O O . HOH S 7 . ? 175.170 41.775 -67.748 1.00 40.82 ? 576 HOH A O 1 HETATM 7236 O O . HOH S 7 . ? 144.421 41.563 -40.695 1.00 37.77 ? 577 HOH A O 1 HETATM 7237 O O . HOH S 7 . ? 146.534 26.137 -39.407 1.00 37.08 ? 578 HOH A O 1 HETATM 7238 O O . HOH S 7 . ? 160.118 46.581 -24.852 1.00 53.52 ? 579 HOH A O 1 HETATM 7239 O O . HOH S 7 . ? 147.531 55.605 -46.387 1.00 29.47 ? 580 HOH A O 1 HETATM 7240 O O . HOH S 7 . ? 127.321 51.974 -50.240 1.00 47.24 ? 581 HOH A O 1 HETATM 7241 O O . HOH S 7 . ? 131.599 47.222 -74.643 1.00 50.13 ? 582 HOH A O 1 HETATM 7242 O O . HOH S 7 . ? 152.837 55.594 -36.930 1.00 42.29 ? 583 HOH A O 1 HETATM 7243 O O . HOH S 7 . ? 164.027 33.006 -28.839 1.00 45.81 ? 584 HOH A O 1 HETATM 7244 O O . HOH S 7 . ? 164.455 39.264 -68.013 1.00 29.00 ? 585 HOH A O 1 HETATM 7245 O O . HOH S 7 . ? 169.441 66.094 -47.373 1.00 36.17 ? 586 HOH A O 1 HETATM 7246 O O . HOH S 7 . ? 178.300 53.586 -57.598 1.00 42.92 ? 587 HOH A O 1 HETATM 7247 O O . HOH S 7 . ? 175.617 33.510 -44.927 1.00 34.61 ? 588 HOH A O 1 HETATM 7248 O O . HOH S 7 . ? 149.211 55.596 -48.909 1.00 34.66 ? 589 HOH A O 1 HETATM 7249 O O . HOH S 7 . ? 147.877 29.529 -52.081 1.00 36.71 ? 590 HOH A O 1 HETATM 7250 O O . HOH S 7 . ? 134.834 54.475 -65.229 1.00 45.69 ? 591 HOH A O 1 HETATM 7251 O O . HOH S 7 . ? 171.288 42.557 -67.007 1.00 37.13 ? 592 HOH A O 1 HETATM 7252 O O . HOH S 7 . ? 167.795 53.209 -27.105 1.00 36.38 ? 593 HOH A O 1 HETATM 7253 O O . HOH S 7 . ? 190.038 34.802 -61.779 1.00 38.93 ? 594 HOH A O 1 HETATM 7254 O O . HOH S 7 . ? 140.584 42.758 -39.835 1.00 42.28 ? 595 HOH A O 1 HETATM 7255 O O . HOH S 7 . ? 124.255 50.291 -49.113 1.00 33.09 ? 596 HOH A O 1 HETATM 7256 O O . HOH S 7 . ? 166.268 51.144 -25.915 1.00 29.49 ? 597 HOH A O 1 HETATM 7257 O O . HOH S 7 . ? 134.964 61.776 -43.443 1.00 39.67 ? 598 HOH A O 1 HETATM 7258 O O . HOH S 7 . ? 138.655 50.989 -68.185 1.00 36.41 ? 599 HOH A O 1 HETATM 7259 O O . HOH S 7 . ? 147.344 58.983 -78.464 1.00 53.33 ? 600 HOH A O 1 HETATM 7260 O O . HOH S 7 . ? 155.283 20.253 -50.485 1.00 37.18 ? 601 HOH A O 1 HETATM 7261 O O . HOH S 7 . ? 165.345 28.333 -33.768 1.00 43.11 ? 602 HOH A O 1 HETATM 7262 O O . HOH S 7 . ? 146.911 66.066 -36.877 1.00 34.79 ? 603 HOH A O 1 HETATM 7263 O O . HOH S 7 . ? 129.198 53.472 -51.985 1.00 32.86 ? 604 HOH A O 1 HETATM 7264 O O . HOH S 7 . ? 151.982 48.345 -23.150 1.00 54.60 ? 605 HOH A O 1 HETATM 7265 O O . HOH S 7 . ? 134.583 38.631 -62.618 1.00 43.09 ? 606 HOH A O 1 HETATM 7266 O O . HOH S 7 . ? 156.387 19.108 -48.053 1.00 46.77 ? 607 HOH A O 1 HETATM 7267 O O . HOH S 7 . ? 179.933 55.840 -59.401 1.00 36.15 ? 608 HOH A O 1 HETATM 7268 O O . HOH S 7 . ? 129.619 44.033 -52.863 1.00 48.07 ? 609 HOH A O 1 HETATM 7269 O O . HOH S 7 . ? 155.098 56.790 -24.501 1.00 48.70 ? 610 HOH A O 1 HETATM 7270 O O . HOH S 7 . ? 134.032 58.086 -67.439 1.00 36.08 ? 611 HOH A O 1 HETATM 7271 O O . HOH S 7 . ? 133.140 44.377 -56.681 1.00 40.76 ? 612 HOH A O 1 HETATM 7272 O O . HOH S 7 . ? 166.273 37.195 -67.470 1.00 31.86 ? 613 HOH A O 1 HETATM 7273 O O . HOH S 7 . ? 170.973 21.752 -57.261 1.00 42.52 ? 614 HOH A O 1 HETATM 7274 O O . HOH S 7 . ? 181.704 52.878 -51.852 1.00 49.03 ? 615 HOH A O 1 HETATM 7275 O O . HOH S 7 . ? 151.382 21.631 -42.488 1.00 43.10 ? 616 HOH A O 1 HETATM 7276 O O . HOH S 7 . ? 165.849 61.472 -36.532 1.00 41.35 ? 617 HOH A O 1 HETATM 7277 O O . HOH S 7 . ? 177.012 35.009 -42.333 1.00 42.21 ? 618 HOH A O 1 HETATM 7278 O O . HOH S 7 . ? 147.728 28.224 -58.586 1.00 37.62 ? 619 HOH A O 1 HETATM 7279 O O . HOH S 7 . ? 123.121 55.409 -45.288 1.00 44.78 ? 620 HOH A O 1 HETATM 7280 O O . HOH S 7 . ? 169.877 37.749 -60.916 1.00 24.79 ? 621 HOH A O 1 HETATM 7281 O O . HOH S 7 . ? 157.609 44.289 -25.956 1.00 45.79 ? 622 HOH A O 1 HETATM 7282 O O . HOH S 7 . ? 146.289 31.642 -34.653 1.00 40.03 ? 623 HOH A O 1 HETATM 7283 O O . HOH S 7 . ? 193.024 43.791 -64.707 1.00 39.55 ? 624 HOH A O 1 HETATM 7284 O O . HOH S 7 . ? 149.972 38.965 -37.888 1.00 36.28 ? 625 HOH A O 1 HETATM 7285 O O . HOH S 7 . ? 149.425 62.552 -48.613 1.00 30.99 ? 626 HOH A O 1 HETATM 7286 O O . HOH S 7 . ? 152.145 20.893 -45.840 1.00 33.60 ? 627 HOH A O 1 HETATM 7287 O O . HOH S 7 . ? 177.241 61.977 -63.105 1.00 41.05 ? 628 HOH A O 1 HETATM 7288 O O . HOH S 7 . ? 154.967 62.011 -65.395 1.00 41.33 ? 629 HOH A O 1 HETATM 7289 O O . HOH S 7 . ? 139.025 47.308 -30.902 1.00 43.86 ? 630 HOH A O 1 HETATM 7290 O O . HOH S 7 . ? 182.617 42.737 -41.017 1.00 37.08 ? 631 HOH A O 1 HETATM 7291 O O . HOH S 7 . ? 169.298 26.570 -65.607 1.00 37.18 ? 632 HOH A O 1 HETATM 7292 O O . HOH S 7 . ? 166.881 63.461 -40.448 1.00 45.35 ? 633 HOH A O 1 HETATM 7293 O O . HOH S 7 . ? 135.122 51.047 -59.339 1.00 35.71 ? 634 HOH A O 1 HETATM 7294 O O . HOH S 7 . ? 130.768 68.813 -47.921 1.00 38.49 ? 635 HOH A O 1 HETATM 7295 O O . HOH S 7 . ? 174.747 47.061 -23.839 1.00 39.17 ? 636 HOH A O 1 HETATM 7296 O O . HOH S 7 . ? 161.412 65.031 -40.738 1.00 42.92 ? 637 HOH A O 1 HETATM 7297 O O . HOH S 7 . ? 183.431 47.046 -58.462 1.00 45.12 ? 638 HOH A O 1 HETATM 7298 O O . HOH S 7 . ? 149.215 21.860 -39.945 1.00 49.30 ? 639 HOH A O 1 HETATM 7299 O O . HOH S 7 . ? 150.582 49.011 -26.436 1.00 42.84 ? 640 HOH A O 1 HETATM 7300 O O . HOH S 7 . ? 135.372 44.974 -64.670 1.00 44.82 ? 641 HOH A O 1 HETATM 7301 O O . HOH S 7 . ? 175.574 51.006 -40.762 1.00 45.87 ? 642 HOH A O 1 HETATM 7302 O O . HOH S 7 . ? 158.873 35.284 -27.189 1.00 46.71 ? 643 HOH A O 1 HETATM 7303 O O . HOH S 7 . ? 157.568 28.091 -33.933 1.00 43.51 ? 644 HOH A O 1 HETATM 7304 O O . HOH S 7 . ? 126.958 39.141 -54.511 1.00 46.64 ? 645 HOH A O 1 HETATM 7305 O O . HOH S 7 . ? 144.038 29.910 -44.077 1.00 34.56 ? 646 HOH A O 1 HETATM 7306 O O . HOH S 7 . ? 135.637 45.417 -48.500 1.00 45.97 ? 647 HOH A O 1 HETATM 7307 O O . HOH S 7 . ? 166.656 60.240 -42.095 1.00 39.67 ? 648 HOH A O 1 HETATM 7308 O O . HOH S 7 . ? 180.695 45.740 -37.644 1.00 49.23 ? 649 HOH A O 1 HETATM 7309 O O . HOH S 7 . ? 165.543 29.092 -30.658 1.00 43.51 ? 650 HOH A O 1 HETATM 7310 O O . HOH S 7 . ? 146.291 66.076 -43.836 1.00 46.20 ? 651 HOH A O 1 HETATM 7311 O O . HOH S 7 . ? 129.555 52.452 -54.359 1.00 47.75 ? 652 HOH A O 1 HETATM 7312 O O . HOH T 7 . ? 181.571 65.400 -67.336 1.00 26.75 ? 454 HOH B O 1 HETATM 7313 O O . HOH T 7 . ? 165.408 46.211 -64.314 1.00 1.00 ? 455 HOH B O 1 HETATM 7314 O O . HOH T 7 . ? 180.955 50.099 -88.874 1.00 12.19 ? 456 HOH B O 1 HETATM 7315 O O . HOH T 7 . ? 156.538 84.123 -63.369 1.00 13.36 ? 457 HOH B O 1 HETATM 7316 O O . HOH T 7 . ? 163.136 58.951 -65.498 1.00 11.28 ? 458 HOH B O 1 HETATM 7317 O O . HOH T 7 . ? 172.581 60.602 -72.140 1.00 15.94 ? 459 HOH B O 1 HETATM 7318 O O . HOH T 7 . ? 186.826 56.888 -72.368 1.00 16.34 ? 460 HOH B O 1 HETATM 7319 O O . HOH T 7 . ? 179.854 45.905 -77.025 1.00 18.22 ? 461 HOH B O 1 HETATM 7320 O O . HOH T 7 . ? 189.227 53.590 -102.168 1.00 34.56 ? 462 HOH B O 1 HETATM 7321 O O . HOH T 7 . ? 195.267 66.628 -84.975 1.00 30.45 ? 463 HOH B O 1 HETATM 7322 O O . HOH T 7 . ? 173.742 90.061 -58.332 1.00 29.06 ? 464 HOH B O 1 HETATM 7323 O O . HOH T 7 . ? 175.536 53.189 -66.573 1.00 10.86 ? 465 HOH B O 1 HETATM 7324 O O . HOH T 7 . ? 166.268 53.013 -90.756 1.00 34.00 ? 466 HOH B O 1 HETATM 7325 O O . HOH T 7 . ? 170.704 61.847 -69.638 1.00 13.16 ? 467 HOH B O 1 HETATM 7326 O O . HOH T 7 . ? 169.656 71.904 -67.548 1.00 18.15 ? 468 HOH B O 1 HETATM 7327 O O . HOH T 7 . ? 182.955 48.366 -69.626 1.00 16.21 ? 469 HOH B O 1 HETATM 7328 O O . HOH T 7 . ? 177.118 51.324 -62.764 1.00 18.69 ? 470 HOH B O 1 HETATM 7329 O O . HOH T 7 . ? 169.952 62.425 -73.988 1.00 16.56 ? 471 HOH B O 1 HETATM 7330 O O . HOH T 7 . ? 181.080 38.249 -71.039 1.00 21.05 ? 472 HOH B O 1 HETATM 7331 O O . HOH T 7 . ? 179.423 54.089 -74.702 1.00 14.71 ? 473 HOH B O 1 HETATM 7332 O O . HOH T 7 . ? 177.726 58.543 -65.399 1.00 17.12 ? 474 HOH B O 1 HETATM 7333 O O . HOH T 7 . ? 189.187 52.592 -99.667 1.00 16.57 ? 475 HOH B O 1 HETATM 7334 O O . HOH T 7 . ? 162.172 55.837 -68.902 1.00 20.91 ? 476 HOH B O 1 HETATM 7335 O O . HOH T 7 . ? 162.572 61.550 -82.791 1.00 29.16 ? 477 HOH B O 1 HETATM 7336 O O . HOH T 7 . ? 170.719 44.976 -65.832 1.00 19.87 ? 478 HOH B O 1 HETATM 7337 O O . HOH T 7 . ? 166.567 71.779 -62.657 1.00 28.67 ? 479 HOH B O 1 HETATM 7338 O O . HOH T 7 . ? 169.795 56.816 -64.949 1.00 23.86 ? 480 HOH B O 1 HETATM 7339 O O . HOH T 7 . ? 183.803 54.994 -75.136 1.00 19.19 ? 481 HOH B O 1 HETATM 7340 O O . HOH T 7 . ? 152.736 97.946 -80.463 1.00 35.12 ? 482 HOH B O 1 HETATM 7341 O O . HOH T 7 . ? 158.516 74.592 -55.133 1.00 31.22 ? 483 HOH B O 1 HETATM 7342 O O . HOH T 7 . ? 179.673 45.542 -63.628 1.00 29.05 ? 484 HOH B O 1 HETATM 7343 O O . HOH T 7 . ? 175.452 72.416 -68.996 1.00 19.87 ? 485 HOH B O 1 HETATM 7344 O O . HOH T 7 . ? 181.753 76.390 -65.856 1.00 23.91 ? 486 HOH B O 1 HETATM 7345 O O . HOH T 7 . ? 182.599 45.338 -70.228 1.00 24.72 ? 487 HOH B O 1 HETATM 7346 O O . HOH T 7 . ? 185.279 68.541 -72.619 1.00 34.20 ? 488 HOH B O 1 HETATM 7347 O O . HOH T 7 . ? 173.596 69.145 -63.155 1.00 25.09 ? 489 HOH B O 1 HETATM 7348 O O . HOH T 7 . ? 170.833 80.829 -61.845 1.00 23.66 ? 490 HOH B O 1 HETATM 7349 O O . HOH T 7 . ? 173.836 55.515 -65.947 1.00 23.85 ? 491 HOH B O 1 HETATM 7350 O O . HOH T 7 . ? 159.140 56.909 -74.416 1.00 17.96 ? 492 HOH B O 1 HETATM 7351 O O . HOH T 7 . ? 173.528 85.559 -80.015 1.00 29.48 ? 493 HOH B O 1 HETATM 7352 O O . HOH T 7 . ? 185.350 49.918 -69.626 1.00 23.61 ? 494 HOH B O 1 HETATM 7353 O O . HOH T 7 . ? 152.906 87.859 -84.445 1.00 27.62 ? 495 HOH B O 1 HETATM 7354 O O . HOH T 7 . ? 160.236 90.314 -82.823 1.00 24.57 ? 496 HOH B O 1 HETATM 7355 O O . HOH T 7 . ? 187.824 68.362 -88.441 1.00 22.07 ? 497 HOH B O 1 HETATM 7356 O O . HOH T 7 . ? 181.812 34.240 -62.330 1.00 24.94 ? 498 HOH B O 1 HETATM 7357 O O . HOH T 7 . ? 180.895 38.891 -75.051 1.00 17.59 ? 499 HOH B O 1 HETATM 7358 O O . HOH T 7 . ? 161.186 57.638 -66.965 1.00 16.19 ? 500 HOH B O 1 HETATM 7359 O O . HOH T 7 . ? 191.369 61.354 -62.181 1.00 36.36 ? 501 HOH B O 1 HETATM 7360 O O . HOH T 7 . ? 174.410 30.936 -61.368 1.00 33.86 ? 502 HOH B O 1 HETATM 7361 O O . HOH T 7 . ? 166.726 46.027 -94.037 1.00 18.28 ? 503 HOH B O 1 HETATM 7362 O O . HOH T 7 . ? 183.814 63.868 -60.721 1.00 22.90 ? 504 HOH B O 1 HETATM 7363 O O . HOH T 7 . ? 172.537 67.199 -60.181 1.00 33.55 ? 505 HOH B O 1 HETATM 7364 O O . HOH T 7 . ? 156.197 91.797 -77.872 1.00 24.95 ? 506 HOH B O 1 HETATM 7365 O O . HOH T 7 . ? 187.912 52.114 -74.883 1.00 25.03 ? 507 HOH B O 1 HETATM 7366 O O . HOH T 7 . ? 172.506 79.416 -79.868 1.00 22.98 ? 508 HOH B O 1 HETATM 7367 O O . HOH T 7 . ? 160.099 76.035 -101.727 1.00 36.06 ? 509 HOH B O 1 HETATM 7368 O O . HOH T 7 . ? 161.184 87.345 -81.857 1.00 32.82 ? 510 HOH B O 1 HETATM 7369 O O . HOH T 7 . ? 177.076 84.810 -54.693 1.00 32.38 ? 511 HOH B O 1 HETATM 7370 O O . HOH T 7 . ? 182.035 54.125 -67.896 1.00 24.93 ? 512 HOH B O 1 HETATM 7371 O O . HOH T 7 . ? 167.981 63.075 -94.542 1.00 23.12 ? 513 HOH B O 1 HETATM 7372 O O . HOH T 7 . ? 171.127 78.501 -74.170 1.00 15.53 ? 514 HOH B O 1 HETATM 7373 O O . HOH T 7 . ? 188.931 61.195 -97.442 1.00 34.56 ? 515 HOH B O 1 HETATM 7374 O O . HOH T 7 . ? 188.944 50.945 -83.455 1.00 19.43 ? 516 HOH B O 1 HETATM 7375 O O . HOH T 7 . ? 173.214 77.230 -78.242 1.00 21.72 ? 517 HOH B O 1 HETATM 7376 O O . HOH T 7 . ? 172.626 73.500 -92.694 1.00 27.37 ? 518 HOH B O 1 HETATM 7377 O O . HOH T 7 . ? 184.668 66.610 -78.665 1.00 25.79 ? 519 HOH B O 1 HETATM 7378 O O . HOH T 7 . ? 169.318 73.545 -81.496 1.00 18.35 ? 520 HOH B O 1 HETATM 7379 O O . HOH T 7 . ? 161.592 68.969 -76.718 1.00 21.78 ? 521 HOH B O 1 HETATM 7380 O O . HOH T 7 . ? 187.475 89.058 -76.230 1.00 25.14 ? 522 HOH B O 1 HETATM 7381 O O . HOH T 7 . ? 165.931 61.942 -63.660 1.00 28.39 ? 523 HOH B O 1 HETATM 7382 O O . HOH T 7 . ? 174.118 73.486 -66.612 1.00 24.33 ? 524 HOH B O 1 HETATM 7383 O O . HOH T 7 . ? 163.304 84.677 -60.491 1.00 20.55 ? 525 HOH B O 1 HETATM 7384 O O . HOH T 7 . ? 181.555 50.966 -67.867 1.00 22.41 ? 526 HOH B O 1 HETATM 7385 O O . HOH T 7 . ? 185.079 30.469 -67.063 1.00 39.55 ? 527 HOH B O 1 HETATM 7386 O O . HOH T 7 . ? 186.616 35.350 -64.323 1.00 32.66 ? 528 HOH B O 1 HETATM 7387 O O . HOH T 7 . ? 189.918 70.923 -87.583 1.00 34.74 ? 529 HOH B O 1 HETATM 7388 O O . HOH T 7 . ? 166.944 43.580 -68.310 1.00 26.91 ? 530 HOH B O 1 HETATM 7389 O O . HOH T 7 . ? 162.574 69.508 -74.101 1.00 24.59 ? 531 HOH B O 1 HETATM 7390 O O . HOH T 7 . ? 185.407 59.438 -60.716 1.00 29.41 ? 532 HOH B O 1 HETATM 7391 O O . HOH T 7 . ? 160.084 62.148 -98.017 1.00 32.11 ? 533 HOH B O 1 HETATM 7392 O O . HOH T 7 . ? 178.925 41.661 -68.346 1.00 29.37 ? 534 HOH B O 1 HETATM 7393 O O . HOH T 7 . ? 197.770 61.330 -73.143 1.00 29.75 ? 535 HOH B O 1 HETATM 7394 O O . HOH T 7 . ? 164.254 61.220 -67.003 1.00 24.46 ? 536 HOH B O 1 HETATM 7395 O O . HOH T 7 . ? 173.792 63.122 -102.170 1.00 42.25 ? 537 HOH B O 1 HETATM 7396 O O . HOH T 7 . ? 167.146 90.726 -77.252 1.00 35.52 ? 538 HOH B O 1 HETATM 7397 O O . HOH T 7 . ? 188.182 85.914 -85.892 1.00 43.49 ? 539 HOH B O 1 HETATM 7398 O O . HOH T 7 . ? 160.202 87.059 -85.040 1.00 38.03 ? 540 HOH B O 1 HETATM 7399 O O . HOH T 7 . ? 194.944 69.870 -76.012 1.00 29.63 ? 541 HOH B O 1 HETATM 7400 O O . HOH T 7 . ? 181.548 62.300 -97.405 1.00 33.42 ? 542 HOH B O 1 HETATM 7401 O O . HOH T 7 . ? 164.110 72.508 -60.851 1.00 33.82 ? 543 HOH B O 1 HETATM 7402 O O . HOH T 7 . ? 176.315 43.141 -70.882 1.00 24.43 ? 544 HOH B O 1 HETATM 7403 O O . HOH T 7 . ? 167.481 84.413 -70.858 1.00 39.22 ? 545 HOH B O 1 HETATM 7404 O O . HOH T 7 . ? 174.393 71.471 -93.376 1.00 35.52 ? 546 HOH B O 1 HETATM 7405 O O . HOH T 7 . ? 187.643 62.653 -94.385 1.00 49.37 ? 547 HOH B O 1 HETATM 7406 O O . HOH T 7 . ? 158.589 77.969 -76.733 1.00 27.63 ? 548 HOH B O 1 HETATM 7407 O O . HOH T 7 . ? 187.608 32.277 -66.768 1.00 47.26 ? 549 HOH B O 1 HETATM 7408 O O . HOH T 7 . ? 175.797 89.623 -57.103 1.00 40.82 ? 550 HOH B O 1 HETATM 7409 O O . HOH T 7 . ? 172.869 39.534 -78.368 1.00 25.63 ? 551 HOH B O 1 HETATM 7410 O O . HOH T 7 . ? 158.205 76.009 -53.128 1.00 39.03 ? 552 HOH B O 1 HETATM 7411 O O . HOH T 7 . ? 159.740 78.493 -63.871 1.00 36.99 ? 553 HOH B O 1 HETATM 7412 O O . HOH T 7 . ? 160.341 53.115 -80.851 1.00 38.20 ? 554 HOH B O 1 HETATM 7413 O O . HOH T 7 . ? 192.711 74.268 -76.538 1.00 28.44 ? 555 HOH B O 1 HETATM 7414 O O . HOH T 7 . ? 185.101 36.147 -70.542 1.00 23.67 ? 556 HOH B O 1 HETATM 7415 O O . HOH T 7 . ? 158.340 66.331 -80.743 1.00 30.06 ? 557 HOH B O 1 HETATM 7416 O O . HOH T 7 . ? 161.798 67.340 -102.453 1.00 35.21 ? 558 HOH B O 1 HETATM 7417 O O . HOH T 7 . ? 181.247 55.279 -76.336 1.00 21.00 ? 559 HOH B O 1 HETATM 7418 O O . HOH T 7 . ? 164.146 87.897 -60.935 1.00 41.05 ? 560 HOH B O 1 HETATM 7419 O O . HOH T 7 . ? 180.206 46.590 -60.669 1.00 29.78 ? 561 HOH B O 1 HETATM 7420 O O . HOH T 7 . ? 180.370 77.773 -87.822 1.00 39.22 ? 562 HOH B O 1 HETATM 7421 O O . HOH T 7 . ? 198.685 54.273 -72.787 1.00 41.78 ? 563 HOH B O 1 HETATM 7422 O O . HOH T 7 . ? 184.787 55.766 -61.116 1.00 43.78 ? 564 HOH B O 1 HETATM 7423 O O . HOH T 7 . ? 188.262 46.464 -83.729 1.00 29.88 ? 565 HOH B O 1 HETATM 7424 O O . HOH T 7 . ? 170.856 86.860 -69.152 1.00 30.65 ? 566 HOH B O 1 HETATM 7425 O O . HOH T 7 . ? 170.578 70.496 -92.124 1.00 47.02 ? 567 HOH B O 1 HETATM 7426 O O . HOH T 7 . ? 161.510 78.031 -60.112 1.00 38.10 ? 568 HOH B O 1 HETATM 7427 O O . HOH T 7 . ? 178.000 44.472 -99.749 1.00 33.33 ? 569 HOH B O 1 HETATM 7428 O O . HOH T 7 . ? 187.162 44.869 -86.262 1.00 40.51 ? 570 HOH B O 1 HETATM 7429 O O . HOH T 7 . ? 193.556 74.320 -70.228 1.00 41.98 ? 571 HOH B O 1 HETATM 7430 O O . HOH T 7 . ? 173.520 72.732 -56.863 1.00 34.24 ? 572 HOH B O 1 HETATM 7431 O O . HOH T 7 . ? 183.078 38.175 -73.219 1.00 36.07 ? 573 HOH B O 1 HETATM 7432 O O . HOH T 7 . ? 181.614 57.155 -67.813 1.00 31.60 ? 574 HOH B O 1 HETATM 7433 O O . HOH T 7 . ? 158.424 63.132 -88.742 1.00 37.07 ? 575 HOH B O 1 HETATM 7434 O O . HOH T 7 . ? 171.112 83.252 -60.630 1.00 37.53 ? 576 HOH B O 1 HETATM 7435 O O . HOH T 7 . ? 166.421 74.594 -82.108 1.00 28.08 ? 577 HOH B O 1 HETATM 7436 O O . HOH T 7 . ? 193.799 56.730 -94.849 1.00 44.37 ? 578 HOH B O 1 HETATM 7437 O O . HOH T 7 . ? 175.997 77.844 -97.463 1.00 40.28 ? 579 HOH B O 1 HETATM 7438 O O . HOH T 7 . ? 160.034 92.842 -90.439 1.00 41.51 ? 580 HOH B O 1 HETATM 7439 O O . HOH T 7 . ? 196.187 75.719 -89.279 1.00 39.66 ? 581 HOH B O 1 HETATM 7440 O O . HOH T 7 . ? 178.685 93.048 -81.974 1.00 45.75 ? 582 HOH B O 1 HETATM 7441 O O . HOH T 7 . ? 165.543 69.001 -74.209 1.00 31.68 ? 583 HOH B O 1 HETATM 7442 O O . HOH T 7 . ? 169.077 92.711 -75.813 1.00 36.55 ? 584 HOH B O 1 HETATM 7443 O O . HOH T 7 . ? 155.762 75.729 -84.681 1.00 33.63 ? 585 HOH B O 1 HETATM 7444 O O . HOH T 7 . ? 162.365 69.589 -67.142 1.00 33.05 ? 586 HOH B O 1 HETATM 7445 O O . HOH T 7 . ? 194.290 47.001 -67.653 1.00 27.46 ? 587 HOH B O 1 HETATM 7446 O O . HOH T 7 . ? 169.994 61.910 -102.176 1.00 33.57 ? 588 HOH B O 1 HETATM 7447 O O . HOH T 7 . ? 170.584 90.646 -73.548 1.00 50.82 ? 589 HOH B O 1 HETATM 7448 O O . HOH T 7 . ? 173.488 43.465 -72.117 1.00 35.02 ? 590 HOH B O 1 HETATM 7449 O O . HOH T 7 . ? 190.570 60.034 -65.753 1.00 44.51 ? 591 HOH B O 1 HETATM 7450 O O . HOH T 7 . ? 188.389 49.302 -85.417 1.00 42.32 ? 592 HOH B O 1 HETATM 7451 O O . HOH T 7 . ? 186.904 61.866 -91.253 1.00 37.19 ? 593 HOH B O 1 HETATM 7452 O O . HOH T 7 . ? 184.355 52.164 -67.739 1.00 26.02 ? 594 HOH B O 1 HETATM 7453 O O . HOH T 7 . ? 194.276 76.606 -83.060 1.00 30.18 ? 595 HOH B O 1 HETATM 7454 O O . HOH T 7 . ? 199.122 65.040 -84.725 1.00 33.80 ? 596 HOH B O 1 HETATM 7455 O O . HOH T 7 . ? 157.361 54.841 -76.262 1.00 35.15 ? 597 HOH B O 1 HETATM 7456 O O . HOH T 7 . ? 199.809 51.823 -71.515 1.00 39.28 ? 598 HOH B O 1 HETATM 7457 O O . HOH T 7 . ? 184.614 65.673 -96.336 1.00 47.00 ? 599 HOH B O 1 HETATM 7458 O O . HOH T 7 . ? 156.570 101.835 -80.615 1.00 32.18 ? 600 HOH B O 1 HETATM 7459 O O . HOH T 7 . ? 177.361 65.183 -61.338 1.00 40.40 ? 601 HOH B O 1 HETATM 7460 O O . HOH T 7 . ? 153.538 81.845 -77.469 1.00 38.25 ? 602 HOH B O 1 HETATM 7461 O O . HOH T 7 . ? 167.627 45.826 -91.784 1.00 33.17 ? 603 HOH B O 1 HETATM 7462 O O . HOH T 7 . ? 166.407 46.379 -87.285 1.00 40.28 ? 604 HOH B O 1 HETATM 7463 O O . HOH T 7 . ? 182.472 57.407 -60.457 1.00 33.58 ? 605 HOH B O 1 HETATM 7464 O O . HOH T 7 . ? 175.707 61.174 -103.948 1.00 42.47 ? 606 HOH B O 1 HETATM 7465 O O . HOH T 7 . ? 158.964 75.347 -64.192 1.00 40.50 ? 607 HOH B O 1 HETATM 7466 O O . HOH T 7 . ? 166.643 73.203 -79.815 1.00 22.19 ? 608 HOH B O 1 HETATM 7467 O O . HOH T 7 . ? 162.446 65.700 -65.796 1.00 39.80 ? 609 HOH B O 1 HETATM 7468 O O . HOH T 7 . ? 155.651 75.243 -91.213 1.00 31.83 ? 610 HOH B O 1 HETATM 7469 O O . HOH T 7 . ? 159.654 74.783 -73.332 1.00 36.01 ? 611 HOH B O 1 HETATM 7470 O O . HOH T 7 . ? 180.173 84.476 -64.462 1.00 37.57 ? 612 HOH B O 1 HETATM 7471 O O . HOH T 7 . ? 161.796 81.146 -58.373 1.00 30.08 ? 613 HOH B O 1 HETATM 7472 O O . HOH T 7 . ? 181.888 54.043 -60.824 1.00 32.49 ? 614 HOH B O 1 HETATM 7473 O O . HOH T 7 . ? 177.220 73.044 -93.735 1.00 49.02 ? 615 HOH B O 1 HETATM 7474 O O . HOH T 7 . ? 157.655 67.357 -87.234 1.00 47.53 ? 616 HOH B O 1 HETATM 7475 O O . HOH T 7 . ? 184.692 73.955 -92.998 1.00 38.06 ? 617 HOH B O 1 HETATM 7476 O O . HOH T 7 . ? 189.971 42.187 -74.791 1.00 48.45 ? 618 HOH B O 1 HETATM 7477 O O . HOH T 7 . ? 171.275 55.912 -102.376 1.00 30.63 ? 619 HOH B O 1 HETATM 7478 O O . HOH T 7 . ? 201.660 66.970 -78.136 1.00 37.93 ? 620 HOH B O 1 HETATM 7479 O O . HOH T 7 . ? 184.839 81.926 -64.495 1.00 49.92 ? 621 HOH B O 1 HETATM 7480 O O . HOH T 7 . ? 184.784 61.895 -59.298 1.00 33.91 ? 622 HOH B O 1 HETATM 7481 O O . HOH T 7 . ? 168.531 64.531 -102.512 1.00 46.62 ? 623 HOH B O 1 HETATM 7482 O O . HOH T 7 . ? 162.372 43.516 -86.268 1.00 49.90 ? 624 HOH B O 1 HETATM 7483 O O . HOH T 7 . ? 163.422 75.751 -50.085 1.00 41.87 ? 625 HOH B O 1 HETATM 7484 O O . HOH T 7 . ? 171.748 97.936 -79.661 1.00 42.94 ? 626 HOH B O 1 HETATM 7485 O O . HOH T 7 . ? 158.874 44.870 -69.617 1.00 39.28 ? 627 HOH B O 1 HETATM 7486 O O . HOH T 7 . ? 194.644 59.228 -92.640 1.00 44.04 ? 628 HOH B O 1 HETATM 7487 O O . HOH T 7 . ? 186.737 35.807 -67.893 1.00 49.09 ? 629 HOH B O 1 HETATM 7488 O O . HOH T 7 . ? 203.222 66.486 -80.549 1.00 48.40 ? 630 HOH B O 1 HETATM 7489 O O . HOH T 7 . ? 155.387 53.721 -78.777 1.00 46.47 ? 631 HOH B O 1 HETATM 7490 O O . HOH T 7 . ? 189.952 57.696 -99.846 1.00 54.51 ? 632 HOH B O 1 HETATM 7491 O O . HOH T 7 . ? 156.935 75.160 -96.094 1.00 41.99 ? 633 HOH B O 1 HETATM 7492 O O . HOH T 7 . ? 190.556 42.944 -93.168 1.00 35.79 ? 634 HOH B O 1 HETATM 7493 O O . HOH T 7 . ? 155.454 84.676 -78.838 1.00 35.65 ? 635 HOH B O 1 HETATM 7494 O O . HOH T 7 . ? 171.874 89.770 -95.365 1.00 51.57 ? 636 HOH B O 1 HETATM 7495 O O . HOH T 7 . ? 175.422 82.799 -97.452 1.00 36.62 ? 637 HOH B O 1 HETATM 7496 O O . HOH T 7 . ? 175.111 47.275 -104.637 1.00 43.30 ? 638 HOH B O 1 HETATM 7497 O O . HOH T 7 . ? 190.951 48.525 -83.751 1.00 33.95 ? 639 HOH B O 1 HETATM 7498 O O . HOH T 7 . ? 173.741 39.895 -83.964 1.00 41.64 ? 640 HOH B O 1 HETATM 7499 O O . HOH T 7 . ? 200.555 70.737 -86.285 1.00 38.00 ? 641 HOH B O 1 HETATM 7500 O O . HOH T 7 . ? 191.326 86.006 -79.721 1.00 45.37 ? 642 HOH B O 1 HETATM 7501 O O . HOH T 7 . ? 173.312 71.804 -101.935 1.00 46.88 ? 643 HOH B O 1 HETATM 7502 O O . HOH T 7 . ? 163.587 78.272 -56.572 1.00 42.07 ? 644 HOH B O 1 HETATM 7503 O O . HOH T 7 . ? 179.633 75.208 -87.923 1.00 37.83 ? 645 HOH B O 1 HETATM 7504 O O . HOH T 7 . ? 161.906 55.410 -86.268 1.00 35.00 ? 646 HOH B O 1 HETATM 7505 O O . HOH T 7 . ? 179.534 39.524 -87.602 1.00 46.09 ? 647 HOH B O 1 HETATM 7506 O O . HOH T 7 . ? 164.174 44.545 -79.820 1.00 32.18 ? 648 HOH B O 1 HETATM 7507 O O . HOH T 7 . ? 181.253 73.735 -90.149 1.00 39.87 ? 649 HOH B O 1 HETATM 7508 O O . HOH T 7 . ? 153.916 82.320 -73.262 1.00 40.92 ? 650 HOH B O 1 HETATM 7509 O O . HOH T 7 . ? 168.306 43.890 -70.953 1.00 46.85 ? 651 HOH B O 1 HETATM 7510 O O . HOH T 7 . ? 172.629 67.307 -56.937 1.00 47.45 ? 652 HOH B O 1 HETATM 7511 O O . HOH T 7 . ? 183.438 87.334 -65.885 1.00 46.36 ? 653 HOH B O 1 HETATM 7512 O O . HOH T 7 . ? 195.542 51.962 -62.932 1.00 33.68 ? 654 HOH B O 1 HETATM 7513 O O . HOH T 7 . ? 154.105 59.923 -78.583 1.00 43.12 ? 655 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 9 9 ARG ARG A . n A 1 2 ASP 2 10 10 ASP ASP A . n A 1 3 MET 3 11 11 MET MET A . n A 1 4 PRO 4 12 12 PRO PRO A . n A 1 5 LEU 5 13 13 LEU LEU A . n A 1 6 ASP 6 14 14 ASP ASP A . n A 1 7 SER 7 15 15 SER SER A . n A 1 8 ASP 8 16 16 ASP ASP A . n A 1 9 VAL 9 17 17 VAL VAL A . n A 1 10 PHE 10 18 18 PHE PHE A . n A 1 11 ARG 11 19 19 ARG ARG A . n A 1 12 VAL 12 20 20 VAL VAL A . n A 1 13 PRO 13 21 21 PRO PRO A . n A 1 14 PRO 14 22 22 PRO PRO A . n A 1 15 GLY 15 23 23 GLY GLY A . n A 1 16 TYR 16 24 24 TYR TYR A . n A 1 17 ASN 17 25 25 ASN ASN A . n A 1 18 ALA 18 26 26 ALA ALA A . n A 1 19 PRO 19 27 27 PRO PRO A . n A 1 20 GLN 20 28 28 GLN GLN A . n A 1 21 GLN 21 29 29 GLN GLN A . n A 1 22 VAL 22 30 30 VAL VAL A . n A 1 23 HIS 23 31 31 HIS HIS A . n A 1 24 ILE 24 32 32 ILE ILE A . n A 1 25 THR 25 33 33 THR THR A . n A 1 26 GLN 26 34 34 GLN GLN A . n A 1 27 GLY 27 35 35 GLY GLY A . n A 1 28 ASP 28 36 36 ASP ASP A . n A 1 29 LEU 29 37 37 LEU LEU A . n A 1 30 VAL 30 38 38 VAL VAL A . n A 1 31 GLY 31 39 39 GLY GLY A . n A 1 32 ARG 32 40 40 ARG ARG A . n A 1 33 ALA 33 41 41 ALA ALA A . n A 1 34 MET 34 42 42 MET MET A . n A 1 35 ILE 35 43 43 ILE ILE A . n A 1 36 ILE 36 44 44 ILE ILE A . n A 1 37 SER 37 45 45 SER SER A . n A 1 38 TRP 38 46 46 TRP TRP A . n A 1 39 VAL 39 47 47 VAL VAL A . n A 1 40 THR 40 48 48 THR THR A . n A 1 41 MET 41 49 49 MET MET A . n A 1 42 ASP 42 50 50 ASP ASP A . n A 1 43 GLU 43 51 51 GLU GLU A . n A 1 44 PRO 44 52 52 PRO PRO A . n A 1 45 GLY 45 53 53 GLY GLY A . n A 1 46 SER 46 54 54 SER SER A . n A 1 47 SER 47 55 55 SER SER A . n A 1 48 ALA 48 56 56 ALA ALA A . n A 1 49 VAL 49 57 57 VAL VAL A . n A 1 50 ARG 50 58 58 ARG ARG A . n A 1 51 TYR 51 59 59 TYR TYR A . n A 1 52 TRP 52 60 60 TRP TRP A . n A 1 53 SER 53 61 61 SER SER A . n A 1 54 GLU 54 62 62 GLU GLU A . n A 1 55 LYS 55 63 63 LYS LYS A . n A 1 56 ASN 56 64 64 ASN ASN A . n A 1 57 GLY 57 65 65 GLY GLY A . n A 1 58 ARG 58 66 66 ARG ARG A . n A 1 59 LYS 59 67 67 LYS LYS A . n A 1 60 ARG 60 68 68 ARG ARG A . n A 1 61 ILE 61 69 69 ILE ILE A . n A 1 62 ALA 62 70 70 ALA ALA A . n A 1 63 LYS 63 71 71 LYS LYS A . n A 1 64 GLY 64 72 72 GLY GLY A . n A 1 65 LYS 65 73 73 LYS LYS A . n A 1 66 MET 66 74 74 MET MET A . n A 1 67 SER 67 75 75 SER SER A . n A 1 68 THR 68 76 76 THR THR A . n A 1 69 TYR 69 77 77 TYR TYR A . n A 1 70 ARG 70 78 78 ARG ARG A . n A 1 71 PHE 71 79 79 PHE PHE A . n A 1 72 PHE 72 80 80 PHE PHE A . n A 1 73 ASN 73 81 81 ASN ASN A . n A 1 74 TYR 74 82 82 TYR TYR A . n A 1 75 SER 75 83 83 SER SER A . n A 1 76 SER 76 84 84 SER SER A . n A 1 77 GLY 77 85 85 GLY GLY A . n A 1 78 PHE 78 86 86 PHE PHE A . n A 1 79 ILE 79 87 87 ILE ILE A . n A 1 80 HIS 80 88 88 HIS HIS A . n A 1 81 HIS 81 89 89 HIS HIS A . n A 1 82 THR 82 90 90 THR THR A . n A 1 83 THR 83 91 91 THR THR A . n A 1 84 ILE 84 92 92 ILE ILE A . n A 1 85 ARG 85 93 93 ARG ARG A . n A 1 86 LYS 86 94 94 LYS LYS A . n A 1 87 LEU 87 95 95 LEU LEU A . n A 1 88 LYS 88 96 96 LYS LYS A . n A 1 89 TYR 89 97 97 TYR TYR A . n A 1 90 ASN 90 98 98 ASN ASN A . n A 1 91 THR 91 99 99 THR THR A . n A 1 92 LYS 92 100 100 LYS LYS A . n A 1 93 TYR 93 101 101 TYR TYR A . n A 1 94 TYR 94 102 102 TYR TYR A . n A 1 95 TYR 95 103 103 TYR TYR A . n A 1 96 GLU 96 104 104 GLU GLU A . n A 1 97 VAL 97 105 105 VAL VAL A . n A 1 98 GLY 98 106 106 GLY GLY A . n A 1 99 LEU 99 107 107 LEU LEU A . n A 1 100 ARG 100 108 108 ARG ARG A . n A 1 101 ASN 101 109 109 ASN ASN A . n A 1 102 THR 102 110 110 THR THR A . n A 1 103 THR 103 111 111 THR THR A . n A 1 104 ARG 104 112 112 ARG ARG A . n A 1 105 ARG 105 113 113 ARG ARG A . n A 1 106 PHE 106 114 114 PHE PHE A . n A 1 107 SER 107 115 115 SER SER A . n A 1 108 PHE 108 116 116 PHE PHE A . n A 1 109 ILE 109 117 117 ILE ILE A . n A 1 110 THR 110 118 118 THR THR A . n A 1 111 PRO 111 119 119 PRO PRO A . n A 1 112 PRO 112 120 120 PRO PRO A . n A 1 113 GLN 113 121 121 GLN GLN A . n A 1 114 THR 114 122 122 THR THR A . n A 1 115 GLY 115 123 123 GLY GLY A . n A 1 116 LEU 116 124 124 LEU LEU A . n A 1 117 ASP 117 125 125 ASP ASP A . n A 1 118 VAL 118 126 126 VAL VAL A . n A 1 119 PRO 119 127 127 PRO PRO A . n A 1 120 TYR 120 128 128 TYR TYR A . n A 1 121 THR 121 129 129 THR THR A . n A 1 122 PHE 122 130 130 PHE PHE A . n A 1 123 GLY 123 131 131 GLY GLY A . n A 1 124 LEU 124 132 132 LEU LEU A . n A 1 125 ILE 125 133 133 ILE ILE A . n A 1 126 GLY 126 134 134 GLY GLY A . n A 1 127 ASP 127 135 135 ASP ASP A . n A 1 128 LEU 128 136 136 LEU LEU A . n A 1 129 GLY 129 137 137 GLY GLY A . n A 1 130 GLN 130 138 138 GLN GLN A . n A 1 131 SER 131 139 139 SER SER A . n A 1 132 PHE 132 140 140 PHE PHE A . n A 1 133 ASP 133 141 141 ASP ASP A . n A 1 134 SER 134 142 142 SER SER A . n A 1 135 ASN 135 143 143 ASN ASN A . n A 1 136 THR 136 144 144 THR THR A . n A 1 137 THR 137 145 145 THR THR A . n A 1 138 LEU 138 146 146 LEU LEU A . n A 1 139 SER 139 147 147 SER SER A . n A 1 140 HIS 140 148 148 HIS HIS A . n A 1 141 TYR 141 149 149 TYR TYR A . n A 1 142 GLU 142 150 150 GLU GLU A . n A 1 143 LEU 143 151 151 LEU LEU A . n A 1 144 SER 144 152 152 SER SER A . n A 1 145 PRO 145 153 153 PRO PRO A . n A 1 146 LYS 146 154 154 LYS LYS A . n A 1 147 LYS 147 155 155 LYS LYS A . n A 1 148 GLY 148 156 156 GLY GLY A . n A 1 149 GLN 149 157 157 GLN GLN A . n A 1 150 THR 150 158 158 THR THR A . n A 1 151 VAL 151 159 159 VAL VAL A . n A 1 152 LEU 152 160 160 LEU LEU A . n A 1 153 PHE 153 161 161 PHE PHE A . n A 1 154 VAL 154 162 162 VAL VAL A . n A 1 155 GLY 155 163 163 GLY GLY A . n A 1 156 ASP 156 164 164 ASP ASP A . n A 1 157 LEU 157 165 165 LEU LEU A . n A 1 158 SER 158 166 166 SER SER A . n A 1 159 TYR 159 167 167 TYR TYR A . n A 1 160 ALA 160 168 168 ALA ALA A . n A 1 161 ASP 161 169 169 ASP ASP A . n A 1 162 ARG 162 170 170 ARG ARG A . n A 1 163 TYR 163 171 171 TYR TYR A . n A 1 164 PRO 164 172 172 PRO PRO A . n A 1 165 ASN 165 173 173 ASN ASN A . n A 1 166 HIS 166 174 174 HIS HIS A . n A 1 167 ASP 167 175 175 ASP ASP A . n A 1 168 ASN 168 176 176 ASN ASN A . n A 1 169 VAL 169 177 177 VAL VAL A . n A 1 170 ARG 170 178 178 ARG ARG A . n A 1 171 TRP 171 179 179 TRP TRP A . n A 1 172 ASP 172 180 180 ASP ASP A . n A 1 173 THR 173 181 181 THR THR A . n A 1 174 TRP 174 182 182 TRP TRP A . n A 1 175 GLY 175 183 183 GLY GLY A . n A 1 176 ARG 176 184 184 ARG ARG A . n A 1 177 PHE 177 185 185 PHE PHE A . n A 1 178 THR 178 186 186 THR THR A . n A 1 179 GLU 179 187 187 GLU GLU A . n A 1 180 ARG 180 188 188 ARG ARG A . n A 1 181 SER 181 189 189 SER SER A . n A 1 182 VAL 182 190 190 VAL VAL A . n A 1 183 ALA 183 191 191 ALA ALA A . n A 1 184 TYR 184 192 192 TYR TYR A . n A 1 185 GLN 185 193 193 GLN GLN A . n A 1 186 PRO 186 194 194 PRO PRO A . n A 1 187 TRP 187 195 195 TRP TRP A . n A 1 188 ILE 188 196 196 ILE ILE A . n A 1 189 TRP 189 197 197 TRP TRP A . n A 1 190 THR 190 198 198 THR THR A . n A 1 191 ALA 191 199 199 ALA ALA A . n A 1 192 GLY 192 200 200 GLY GLY A . n A 1 193 ASN 193 201 201 ASN ASN A . n A 1 194 HIS 194 202 202 HIS HIS A . n A 1 195 GLU 195 203 203 GLU GLU A . n A 1 196 ILE 196 204 204 ILE ILE A . n A 1 197 GLU 197 205 205 GLU GLU A . n A 1 198 PHE 198 206 206 PHE PHE A . n A 1 199 ALA 199 207 207 ALA ALA A . n A 1 200 PRO 200 208 208 PRO PRO A . n A 1 201 GLU 201 209 209 GLU GLU A . n A 1 202 ILE 202 210 210 ILE ILE A . n A 1 203 ASN 203 211 211 ASN ASN A . n A 1 204 GLU 204 212 212 GLU GLU A . n A 1 205 THR 205 213 213 THR THR A . n A 1 206 GLU 206 214 214 GLU GLU A . n A 1 207 PRO 207 215 215 PRO PRO A . n A 1 208 PHE 208 216 216 PHE PHE A . n A 1 209 LYS 209 217 217 LYS LYS A . n A 1 210 PRO 210 218 218 PRO PRO A . n A 1 211 PHE 211 219 219 PHE PHE A . n A 1 212 SER 212 220 220 SER SER A . n A 1 213 TYR 213 221 221 TYR TYR A . n A 1 214 ARG 214 222 222 ARG ARG A . n A 1 215 TYR 215 223 223 TYR TYR A . n A 1 216 HIS 216 224 224 HIS HIS A . n A 1 217 VAL 217 225 225 VAL VAL A . n A 1 218 PRO 218 226 226 PRO PRO A . n A 1 219 TYR 219 227 227 TYR TYR A . n A 1 220 GLU 220 228 228 GLU GLU A . n A 1 221 ALA 221 229 229 ALA ALA A . n A 1 222 SER 222 230 230 SER SER A . n A 1 223 GLN 223 231 231 GLN GLN A . n A 1 224 SER 224 232 232 SER SER A . n A 1 225 THR 225 233 233 THR THR A . n A 1 226 SER 226 234 234 SER SER A . n A 1 227 PRO 227 235 235 PRO PRO A . n A 1 228 PHE 228 236 236 PHE PHE A . n A 1 229 TRP 229 237 237 TRP TRP A . n A 1 230 TYR 230 238 238 TYR TYR A . n A 1 231 SER 231 239 239 SER SER A . n A 1 232 ILE 232 240 240 ILE ILE A . n A 1 233 LYS 233 241 241 LYS LYS A . n A 1 234 ARG 234 242 242 ARG ARG A . n A 1 235 ALA 235 243 243 ALA ALA A . n A 1 236 SER 236 244 244 SER SER A . n A 1 237 ALA 237 245 245 ALA ALA A . n A 1 238 HIS 238 246 246 HIS HIS A . n A 1 239 ILE 239 247 247 ILE ILE A . n A 1 240 ILE 240 248 248 ILE ILE A . n A 1 241 VAL 241 249 249 VAL VAL A . n A 1 242 LEU 242 250 250 LEU LEU A . n A 1 243 SER 243 251 251 SER SER A . n A 1 244 SER 244 252 252 SER SER A . n A 1 245 TYR 245 253 253 TYR TYR A . n A 1 246 SER 246 254 254 SER SER A . n A 1 247 ALA 247 255 255 ALA ALA A . n A 1 248 TYR 248 256 256 TYR TYR A . n A 1 249 GLY 249 257 257 GLY GLY A . n A 1 250 ARG 250 258 258 ARG ARG A . n A 1 251 GLY 251 259 259 GLY GLY A . n A 1 252 THR 252 260 260 THR THR A . n A 1 253 PRO 253 261 261 PRO PRO A . n A 1 254 GLN 254 262 262 GLN GLN A . n A 1 255 TYR 255 263 263 TYR TYR A . n A 1 256 THR 256 264 264 THR THR A . n A 1 257 TRP 257 265 265 TRP TRP A . n A 1 258 LEU 258 266 266 LEU LEU A . n A 1 259 LYS 259 267 267 LYS LYS A . n A 1 260 LYS 260 268 268 LYS LYS A . n A 1 261 GLU 261 269 269 GLU GLU A . n A 1 262 LEU 262 270 270 LEU LEU A . n A 1 263 ARG 263 271 271 ARG ARG A . n A 1 264 LYS 264 272 272 LYS LYS A . n A 1 265 VAL 265 273 273 VAL VAL A . n A 1 266 LYS 266 274 274 LYS LYS A . n A 1 267 ARG 267 275 275 ARG ARG A . n A 1 268 SER 268 276 276 SER SER A . n A 1 269 GLU 269 277 277 GLU GLU A . n A 1 270 THR 270 278 278 THR THR A . n A 1 271 PRO 271 279 279 PRO PRO A . n A 1 272 TRP 272 280 280 TRP TRP A . n A 1 273 LEU 273 281 281 LEU LEU A . n A 1 274 ILE 274 282 282 ILE ILE A . n A 1 275 VAL 275 283 283 VAL VAL A . n A 1 276 LEU 276 284 284 LEU LEU A . n A 1 277 MET 277 285 285 MET MET A . n A 1 278 HIS 278 286 286 HIS HIS A . n A 1 279 SER 279 287 287 SER SER A . n A 1 280 PRO 280 288 288 PRO PRO A . n A 1 281 LEU 281 289 289 LEU LEU A . n A 1 282 TYR 282 290 290 TYR TYR A . n A 1 283 ASN 283 291 291 ASN ASN A . n A 1 284 SER 284 292 292 SER SER A . n A 1 285 TYR 285 293 293 TYR TYR A . n A 1 286 ASN 286 294 294 ASN ASN A . n A 1 287 HIS 287 295 295 HIS HIS A . n A 1 288 HIS 288 296 296 HIS HIS A . n A 1 289 PHE 289 297 297 PHE PHE A . n A 1 290 MET 290 298 298 MET MET A . n A 1 291 GLU 291 299 299 GLU GLU A . n A 1 292 GLY 292 300 300 GLY GLY A . n A 1 293 GLU 293 301 301 GLU GLU A . n A 1 294 ALA 294 302 302 ALA ALA A . n A 1 295 MET 295 303 303 MET MET A . n A 1 296 ARG 296 304 304 ARG ARG A . n A 1 297 THR 297 305 305 THR THR A . n A 1 298 LYS 298 306 306 LYS LYS A . n A 1 299 PHE 299 307 307 PHE PHE A . n A 1 300 GLU 300 308 308 GLU GLU A . n A 1 301 ALA 301 309 309 ALA ALA A . n A 1 302 TRP 302 310 310 TRP TRP A . n A 1 303 PHE 303 311 311 PHE PHE A . n A 1 304 VAL 304 312 312 VAL VAL A . n A 1 305 LYS 305 313 313 LYS LYS A . n A 1 306 TYR 306 314 314 TYR TYR A . n A 1 307 LYS 307 315 315 LYS LYS A . n A 1 308 VAL 308 316 316 VAL VAL A . n A 1 309 ASP 309 317 317 ASP ASP A . n A 1 310 VAL 310 318 318 VAL VAL A . n A 1 311 VAL 311 319 319 VAL VAL A . n A 1 312 PHE 312 320 320 PHE PHE A . n A 1 313 ALA 313 321 321 ALA ALA A . n A 1 314 GLY 314 322 322 GLY GLY A . n A 1 315 HIS 315 323 323 HIS HIS A . n A 1 316 VAL 316 324 324 VAL VAL A . n A 1 317 HIS 317 325 325 HIS HIS A . n A 1 318 ALA 318 326 326 ALA ALA A . n A 1 319 TYR 319 327 327 TYR TYR A . n A 1 320 GLU 320 328 328 GLU GLU A . n A 1 321 ARG 321 329 329 ARG ARG A . n A 1 322 SER 322 330 330 SER SER A . n A 1 323 GLU 323 331 331 GLU GLU A . n A 1 324 ARG 324 332 332 ARG ARG A . n A 1 325 VAL 325 333 333 VAL VAL A . n A 1 326 SER 326 334 334 SER SER A . n A 1 327 ASN 327 335 335 ASN ASN A . n A 1 328 ILE 328 336 336 ILE ILE A . n A 1 329 ALA 329 337 337 ALA ALA A . n A 1 330 TYR 330 338 338 TYR TYR A . n A 1 331 LYS 331 339 339 LYS LYS A . n A 1 332 ILE 332 340 340 ILE ILE A . n A 1 333 THR 333 341 341 THR THR A . n A 1 334 ASN 334 342 342 ASN ASN A . n A 1 335 GLY 335 343 343 GLY GLY A . n A 1 336 LEU 336 344 344 LEU LEU A . n A 1 337 CYS 337 345 345 CYS CYS A . n A 1 338 THR 338 346 346 THR THR A . n A 1 339 PRO 339 347 347 PRO PRO A . n A 1 340 VAL 340 348 348 VAL VAL A . n A 1 341 LYS 341 349 349 LYS LYS A . n A 1 342 ASP 342 350 350 ASP ASP A . n A 1 343 GLN 343 351 351 GLN GLN A . n A 1 344 SER 344 352 352 SER SER A . n A 1 345 ALA 345 353 353 ALA ALA A . n A 1 346 PRO 346 354 354 PRO PRO A . n A 1 347 VAL 347 355 355 VAL VAL A . n A 1 348 TYR 348 356 356 TYR TYR A . n A 1 349 ILE 349 357 357 ILE ILE A . n A 1 350 THR 350 358 358 THR THR A . n A 1 351 ILE 351 359 359 ILE ILE A . n A 1 352 GLY 352 360 360 GLY GLY A . n A 1 353 ASP 353 361 361 ASP ASP A . n A 1 354 ALA 354 362 362 ALA ALA A . n A 1 355 GLY 355 363 363 GLY GLY A . n A 1 356 ASN 356 364 364 ASN ASN A . n A 1 357 TYR 357 365 365 TYR TYR A . n A 1 358 GLY 358 366 366 GLY GLY A . n A 1 359 VAL 359 367 367 VAL VAL A . n A 1 360 ILE 360 368 368 ILE ILE A . n A 1 361 ASP 361 369 369 ASP ASP A . n A 1 362 SER 362 370 370 SER SER A . n A 1 363 ASN 363 371 371 ASN ASN A . n A 1 364 MET 364 372 372 MET MET A . n A 1 365 ILE 365 373 373 ILE ILE A . n A 1 366 GLN 366 374 374 GLN GLN A . n A 1 367 PRO 367 375 375 PRO PRO A . n A 1 368 GLN 368 376 376 GLN GLN A . n A 1 369 PRO 369 377 377 PRO PRO A . n A 1 370 GLU 370 378 378 GLU GLU A . n A 1 371 TYR 371 379 379 TYR TYR A . n A 1 372 SER 372 380 380 SER SER A . n A 1 373 ALA 373 381 381 ALA ALA A . n A 1 374 PHE 374 382 382 PHE PHE A . n A 1 375 ARG 375 383 383 ARG ARG A . n A 1 376 GLU 376 384 384 GLU GLU A . n A 1 377 ALA 377 385 385 ALA ALA A . n A 1 378 SER 378 386 386 SER SER A . n A 1 379 PHE 379 387 387 PHE PHE A . n A 1 380 GLY 380 388 388 GLY GLY A . n A 1 381 HIS 381 389 389 HIS HIS A . n A 1 382 GLY 382 390 390 GLY GLY A . n A 1 383 MET 383 391 391 MET MET A . n A 1 384 PHE 384 392 392 PHE PHE A . n A 1 385 ASP 385 393 393 ASP ASP A . n A 1 386 ILE 386 394 394 ILE ILE A . n A 1 387 LYS 387 395 395 LYS LYS A . n A 1 388 ASN 388 396 396 ASN ASN A . n A 1 389 ARG 389 397 397 ARG ARG A . n A 1 390 THR 390 398 398 THR THR A . n A 1 391 HIS 391 399 399 HIS HIS A . n A 1 392 ALA 392 400 400 ALA ALA A . n A 1 393 HIS 393 401 401 HIS HIS A . n A 1 394 PHE 394 402 402 PHE PHE A . n A 1 395 SER 395 403 403 SER SER A . n A 1 396 TRP 396 404 404 TRP TRP A . n A 1 397 ASN 397 405 405 ASN ASN A . n A 1 398 ARG 398 406 406 ARG ARG A . n A 1 399 ASN 399 407 407 ASN ASN A . n A 1 400 GLN 400 408 408 GLN GLN A . n A 1 401 ASP 401 409 409 ASP ASP A . n A 1 402 GLY 402 410 410 GLY GLY A . n A 1 403 VAL 403 411 411 VAL VAL A . n A 1 404 ALA 404 412 412 ALA ALA A . n A 1 405 VAL 405 413 413 VAL VAL A . n A 1 406 GLU 406 414 414 GLU GLU A . n A 1 407 ALA 407 415 415 ALA ALA A . n A 1 408 ASP 408 416 416 ASP ASP A . n A 1 409 SER 409 417 417 SER SER A . n A 1 410 VAL 410 418 418 VAL VAL A . n A 1 411 TRP 411 419 419 TRP TRP A . n A 1 412 PHE 412 420 420 PHE PHE A . n A 1 413 PHE 413 421 421 PHE PHE A . n A 1 414 ASN 414 422 422 ASN ASN A . n A 1 415 ARG 415 423 423 ARG ARG A . n A 1 416 HIS 416 424 424 HIS HIS A . n A 1 417 TRP 417 425 425 TRP TRP A . n A 1 418 TYR 418 426 426 TYR TYR A . n A 1 419 PRO 419 427 427 PRO PRO A . n A 1 420 VAL 420 428 428 VAL VAL A . n A 1 421 ASP 421 429 429 ASP ASP A . n A 1 422 ASP 422 430 430 ASP ASP A . n A 1 423 SER 423 431 431 SER SER A . n A 1 424 THR 424 432 432 THR THR A . n B 1 1 ARG 1 9 9 ARG ARG B . n B 1 2 ASP 2 10 10 ASP ASP B . n B 1 3 MET 3 11 11 MET MET B . n B 1 4 PRO 4 12 12 PRO PRO B . n B 1 5 LEU 5 13 13 LEU LEU B . n B 1 6 ASP 6 14 14 ASP ASP B . n B 1 7 SER 7 15 15 SER SER B . n B 1 8 ASP 8 16 16 ASP ASP B . n B 1 9 VAL 9 17 17 VAL VAL B . n B 1 10 PHE 10 18 18 PHE PHE B . n B 1 11 ARG 11 19 19 ARG ARG B . n B 1 12 VAL 12 20 20 VAL VAL B . n B 1 13 PRO 13 21 21 PRO PRO B . n B 1 14 PRO 14 22 22 PRO PRO B . n B 1 15 GLY 15 23 23 GLY GLY B . n B 1 16 TYR 16 24 24 TYR TYR B . n B 1 17 ASN 17 25 25 ASN ASN B . n B 1 18 ALA 18 26 26 ALA ALA B . n B 1 19 PRO 19 27 27 PRO PRO B . n B 1 20 GLN 20 28 28 GLN GLN B . n B 1 21 GLN 21 29 29 GLN GLN B . n B 1 22 VAL 22 30 30 VAL VAL B . n B 1 23 HIS 23 31 31 HIS HIS B . n B 1 24 ILE 24 32 32 ILE ILE B . n B 1 25 THR 25 33 33 THR THR B . n B 1 26 GLN 26 34 34 GLN GLN B . n B 1 27 GLY 27 35 35 GLY GLY B . n B 1 28 ASP 28 36 36 ASP ASP B . n B 1 29 LEU 29 37 37 LEU LEU B . n B 1 30 VAL 30 38 38 VAL VAL B . n B 1 31 GLY 31 39 39 GLY GLY B . n B 1 32 ARG 32 40 40 ARG ARG B . n B 1 33 ALA 33 41 41 ALA ALA B . n B 1 34 MET 34 42 42 MET MET B . n B 1 35 ILE 35 43 43 ILE ILE B . n B 1 36 ILE 36 44 44 ILE ILE B . n B 1 37 SER 37 45 45 SER SER B . n B 1 38 TRP 38 46 46 TRP TRP B . n B 1 39 VAL 39 47 47 VAL VAL B . n B 1 40 THR 40 48 48 THR THR B . n B 1 41 MET 41 49 49 MET MET B . n B 1 42 ASP 42 50 50 ASP ASP B . n B 1 43 GLU 43 51 51 GLU GLU B . n B 1 44 PRO 44 52 52 PRO PRO B . n B 1 45 GLY 45 53 53 GLY GLY B . n B 1 46 SER 46 54 54 SER SER B . n B 1 47 SER 47 55 55 SER SER B . n B 1 48 ALA 48 56 56 ALA ALA B . n B 1 49 VAL 49 57 57 VAL VAL B . n B 1 50 ARG 50 58 58 ARG ARG B . n B 1 51 TYR 51 59 59 TYR TYR B . n B 1 52 TRP 52 60 60 TRP TRP B . n B 1 53 SER 53 61 61 SER SER B . n B 1 54 GLU 54 62 62 GLU GLU B . n B 1 55 LYS 55 63 63 LYS LYS B . n B 1 56 ASN 56 64 64 ASN ASN B . n B 1 57 GLY 57 65 65 GLY GLY B . n B 1 58 ARG 58 66 66 ARG ARG B . n B 1 59 LYS 59 67 67 LYS LYS B . n B 1 60 ARG 60 68 68 ARG ARG B . n B 1 61 ILE 61 69 69 ILE ILE B . n B 1 62 ALA 62 70 70 ALA ALA B . n B 1 63 LYS 63 71 71 LYS LYS B . n B 1 64 GLY 64 72 72 GLY GLY B . n B 1 65 LYS 65 73 73 LYS LYS B . n B 1 66 MET 66 74 74 MET MET B . n B 1 67 SER 67 75 75 SER SER B . n B 1 68 THR 68 76 76 THR THR B . n B 1 69 TYR 69 77 77 TYR TYR B . n B 1 70 ARG 70 78 78 ARG ARG B . n B 1 71 PHE 71 79 79 PHE PHE B . n B 1 72 PHE 72 80 80 PHE PHE B . n B 1 73 ASN 73 81 81 ASN ASN B . n B 1 74 TYR 74 82 82 TYR TYR B . n B 1 75 SER 75 83 83 SER SER B . n B 1 76 SER 76 84 84 SER SER B . n B 1 77 GLY 77 85 85 GLY GLY B . n B 1 78 PHE 78 86 86 PHE PHE B . n B 1 79 ILE 79 87 87 ILE ILE B . n B 1 80 HIS 80 88 88 HIS HIS B . n B 1 81 HIS 81 89 89 HIS HIS B . n B 1 82 THR 82 90 90 THR THR B . n B 1 83 THR 83 91 91 THR THR B . n B 1 84 ILE 84 92 92 ILE ILE B . n B 1 85 ARG 85 93 93 ARG ARG B . n B 1 86 LYS 86 94 94 LYS LYS B . n B 1 87 LEU 87 95 95 LEU LEU B . n B 1 88 LYS 88 96 96 LYS LYS B . n B 1 89 TYR 89 97 97 TYR TYR B . n B 1 90 ASN 90 98 98 ASN ASN B . n B 1 91 THR 91 99 99 THR THR B . n B 1 92 LYS 92 100 100 LYS LYS B . n B 1 93 TYR 93 101 101 TYR TYR B . n B 1 94 TYR 94 102 102 TYR TYR B . n B 1 95 TYR 95 103 103 TYR TYR B . n B 1 96 GLU 96 104 104 GLU GLU B . n B 1 97 VAL 97 105 105 VAL VAL B . n B 1 98 GLY 98 106 106 GLY GLY B . n B 1 99 LEU 99 107 107 LEU LEU B . n B 1 100 ARG 100 108 108 ARG ARG B . n B 1 101 ASN 101 109 109 ASN ASN B . n B 1 102 THR 102 110 110 THR THR B . n B 1 103 THR 103 111 111 THR THR B . n B 1 104 ARG 104 112 112 ARG ARG B . n B 1 105 ARG 105 113 113 ARG ARG B . n B 1 106 PHE 106 114 114 PHE PHE B . n B 1 107 SER 107 115 115 SER SER B . n B 1 108 PHE 108 116 116 PHE PHE B . n B 1 109 ILE 109 117 117 ILE ILE B . n B 1 110 THR 110 118 118 THR THR B . n B 1 111 PRO 111 119 119 PRO PRO B . n B 1 112 PRO 112 120 120 PRO PRO B . n B 1 113 GLN 113 121 121 GLN GLN B . n B 1 114 THR 114 122 122 THR THR B . n B 1 115 GLY 115 123 123 GLY GLY B . n B 1 116 LEU 116 124 124 LEU LEU B . n B 1 117 ASP 117 125 125 ASP ASP B . n B 1 118 VAL 118 126 126 VAL VAL B . n B 1 119 PRO 119 127 127 PRO PRO B . n B 1 120 TYR 120 128 128 TYR TYR B . n B 1 121 THR 121 129 129 THR THR B . n B 1 122 PHE 122 130 130 PHE PHE B . n B 1 123 GLY 123 131 131 GLY GLY B . n B 1 124 LEU 124 132 132 LEU LEU B . n B 1 125 ILE 125 133 133 ILE ILE B . n B 1 126 GLY 126 134 134 GLY GLY B . n B 1 127 ASP 127 135 135 ASP ASP B . n B 1 128 LEU 128 136 136 LEU LEU B . n B 1 129 GLY 129 137 137 GLY GLY B . n B 1 130 GLN 130 138 138 GLN GLN B . n B 1 131 SER 131 139 139 SER SER B . n B 1 132 PHE 132 140 140 PHE PHE B . n B 1 133 ASP 133 141 141 ASP ASP B . n B 1 134 SER 134 142 142 SER SER B . n B 1 135 ASN 135 143 143 ASN ASN B . n B 1 136 THR 136 144 144 THR THR B . n B 1 137 THR 137 145 145 THR THR B . n B 1 138 LEU 138 146 146 LEU LEU B . n B 1 139 SER 139 147 147 SER SER B . n B 1 140 HIS 140 148 148 HIS HIS B . n B 1 141 TYR 141 149 149 TYR TYR B . n B 1 142 GLU 142 150 150 GLU GLU B . n B 1 143 LEU 143 151 151 LEU LEU B . n B 1 144 SER 144 152 152 SER SER B . n B 1 145 PRO 145 153 153 PRO PRO B . n B 1 146 LYS 146 154 154 LYS LYS B . n B 1 147 LYS 147 155 155 LYS LYS B . n B 1 148 GLY 148 156 156 GLY GLY B . n B 1 149 GLN 149 157 157 GLN GLN B . n B 1 150 THR 150 158 158 THR THR B . n B 1 151 VAL 151 159 159 VAL VAL B . n B 1 152 LEU 152 160 160 LEU LEU B . n B 1 153 PHE 153 161 161 PHE PHE B . n B 1 154 VAL 154 162 162 VAL VAL B . n B 1 155 GLY 155 163 163 GLY GLY B . n B 1 156 ASP 156 164 164 ASP ASP B . n B 1 157 LEU 157 165 165 LEU LEU B . n B 1 158 SER 158 166 166 SER SER B . n B 1 159 TYR 159 167 167 TYR TYR B . n B 1 160 ALA 160 168 168 ALA ALA B . n B 1 161 ASP 161 169 169 ASP ASP B . n B 1 162 ARG 162 170 170 ARG ARG B . n B 1 163 TYR 163 171 171 TYR TYR B . n B 1 164 PRO 164 172 172 PRO PRO B . n B 1 165 ASN 165 173 173 ASN ASN B . n B 1 166 HIS 166 174 174 HIS HIS B . n B 1 167 ASP 167 175 175 ASP ASP B . n B 1 168 ASN 168 176 176 ASN ASN B . n B 1 169 VAL 169 177 177 VAL VAL B . n B 1 170 ARG 170 178 178 ARG ARG B . n B 1 171 TRP 171 179 179 TRP TRP B . n B 1 172 ASP 172 180 180 ASP ASP B . n B 1 173 THR 173 181 181 THR THR B . n B 1 174 TRP 174 182 182 TRP TRP B . n B 1 175 GLY 175 183 183 GLY GLY B . n B 1 176 ARG 176 184 184 ARG ARG B . n B 1 177 PHE 177 185 185 PHE PHE B . n B 1 178 THR 178 186 186 THR THR B . n B 1 179 GLU 179 187 187 GLU GLU B . n B 1 180 ARG 180 188 188 ARG ARG B . n B 1 181 SER 181 189 189 SER SER B . n B 1 182 VAL 182 190 190 VAL VAL B . n B 1 183 ALA 183 191 191 ALA ALA B . n B 1 184 TYR 184 192 192 TYR TYR B . n B 1 185 GLN 185 193 193 GLN GLN B . n B 1 186 PRO 186 194 194 PRO PRO B . n B 1 187 TRP 187 195 195 TRP TRP B . n B 1 188 ILE 188 196 196 ILE ILE B . n B 1 189 TRP 189 197 197 TRP TRP B . n B 1 190 THR 190 198 198 THR THR B . n B 1 191 ALA 191 199 199 ALA ALA B . n B 1 192 GLY 192 200 200 GLY GLY B . n B 1 193 ASN 193 201 201 ASN ASN B . n B 1 194 HIS 194 202 202 HIS HIS B . n B 1 195 GLU 195 203 203 GLU GLU B . n B 1 196 ILE 196 204 204 ILE ILE B . n B 1 197 GLU 197 205 205 GLU GLU B . n B 1 198 PHE 198 206 206 PHE PHE B . n B 1 199 ALA 199 207 207 ALA ALA B . n B 1 200 PRO 200 208 208 PRO PRO B . n B 1 201 GLU 201 209 209 GLU GLU B . n B 1 202 ILE 202 210 210 ILE ILE B . n B 1 203 ASN 203 211 211 ASN ASN B . n B 1 204 GLU 204 212 212 GLU GLU B . n B 1 205 THR 205 213 213 THR THR B . n B 1 206 GLU 206 214 214 GLU GLU B . n B 1 207 PRO 207 215 215 PRO PRO B . n B 1 208 PHE 208 216 216 PHE PHE B . n B 1 209 LYS 209 217 217 LYS LYS B . n B 1 210 PRO 210 218 218 PRO PRO B . n B 1 211 PHE 211 219 219 PHE PHE B . n B 1 212 SER 212 220 220 SER SER B . n B 1 213 TYR 213 221 221 TYR TYR B . n B 1 214 ARG 214 222 222 ARG ARG B . n B 1 215 TYR 215 223 223 TYR TYR B . n B 1 216 HIS 216 224 224 HIS HIS B . n B 1 217 VAL 217 225 225 VAL VAL B . n B 1 218 PRO 218 226 226 PRO PRO B . n B 1 219 TYR 219 227 227 TYR TYR B . n B 1 220 GLU 220 228 228 GLU GLU B . n B 1 221 ALA 221 229 229 ALA ALA B . n B 1 222 SER 222 230 230 SER SER B . n B 1 223 GLN 223 231 231 GLN GLN B . n B 1 224 SER 224 232 232 SER SER B . n B 1 225 THR 225 233 233 THR THR B . n B 1 226 SER 226 234 234 SER SER B . n B 1 227 PRO 227 235 235 PRO PRO B . n B 1 228 PHE 228 236 236 PHE PHE B . n B 1 229 TRP 229 237 237 TRP TRP B . n B 1 230 TYR 230 238 238 TYR TYR B . n B 1 231 SER 231 239 239 SER SER B . n B 1 232 ILE 232 240 240 ILE ILE B . n B 1 233 LYS 233 241 241 LYS LYS B . n B 1 234 ARG 234 242 242 ARG ARG B . n B 1 235 ALA 235 243 243 ALA ALA B . n B 1 236 SER 236 244 244 SER SER B . n B 1 237 ALA 237 245 245 ALA ALA B . n B 1 238 HIS 238 246 246 HIS HIS B . n B 1 239 ILE 239 247 247 ILE ILE B . n B 1 240 ILE 240 248 248 ILE ILE B . n B 1 241 VAL 241 249 249 VAL VAL B . n B 1 242 LEU 242 250 250 LEU LEU B . n B 1 243 SER 243 251 251 SER SER B . n B 1 244 SER 244 252 252 SER SER B . n B 1 245 TYR 245 253 253 TYR TYR B . n B 1 246 SER 246 254 254 SER SER B . n B 1 247 ALA 247 255 255 ALA ALA B . n B 1 248 TYR 248 256 256 TYR TYR B . n B 1 249 GLY 249 257 257 GLY GLY B . n B 1 250 ARG 250 258 258 ARG ARG B . n B 1 251 GLY 251 259 259 GLY GLY B . n B 1 252 THR 252 260 260 THR THR B . n B 1 253 PRO 253 261 261 PRO PRO B . n B 1 254 GLN 254 262 262 GLN GLN B . n B 1 255 TYR 255 263 263 TYR TYR B . n B 1 256 THR 256 264 264 THR THR B . n B 1 257 TRP 257 265 265 TRP TRP B . n B 1 258 LEU 258 266 266 LEU LEU B . n B 1 259 LYS 259 267 267 LYS LYS B . n B 1 260 LYS 260 268 268 LYS LYS B . n B 1 261 GLU 261 269 269 GLU GLU B . n B 1 262 LEU 262 270 270 LEU LEU B . n B 1 263 ARG 263 271 271 ARG ARG B . n B 1 264 LYS 264 272 272 LYS LYS B . n B 1 265 VAL 265 273 273 VAL VAL B . n B 1 266 LYS 266 274 274 LYS LYS B . n B 1 267 ARG 267 275 275 ARG ARG B . n B 1 268 SER 268 276 276 SER SER B . n B 1 269 GLU 269 277 277 GLU GLU B . n B 1 270 THR 270 278 278 THR THR B . n B 1 271 PRO 271 279 279 PRO PRO B . n B 1 272 TRP 272 280 280 TRP TRP B . n B 1 273 LEU 273 281 281 LEU LEU B . n B 1 274 ILE 274 282 282 ILE ILE B . n B 1 275 VAL 275 283 283 VAL VAL B . n B 1 276 LEU 276 284 284 LEU LEU B . n B 1 277 MET 277 285 285 MET MET B . n B 1 278 HIS 278 286 286 HIS HIS B . n B 1 279 SER 279 287 287 SER SER B . n B 1 280 PRO 280 288 288 PRO PRO B . n B 1 281 LEU 281 289 289 LEU LEU B . n B 1 282 TYR 282 290 290 TYR TYR B . n B 1 283 ASN 283 291 291 ASN ASN B . n B 1 284 SER 284 292 292 SER SER B . n B 1 285 TYR 285 293 293 TYR TYR B . n B 1 286 ASN 286 294 294 ASN ASN B . n B 1 287 HIS 287 295 295 HIS HIS B . n B 1 288 HIS 288 296 296 HIS HIS B . n B 1 289 PHE 289 297 297 PHE PHE B . n B 1 290 MET 290 298 298 MET MET B . n B 1 291 GLU 291 299 299 GLU GLU B . n B 1 292 GLY 292 300 300 GLY GLY B . n B 1 293 GLU 293 301 301 GLU GLU B . n B 1 294 ALA 294 302 302 ALA ALA B . n B 1 295 MET 295 303 303 MET MET B . n B 1 296 ARG 296 304 304 ARG ARG B . n B 1 297 THR 297 305 305 THR THR B . n B 1 298 LYS 298 306 306 LYS LYS B . n B 1 299 PHE 299 307 307 PHE PHE B . n B 1 300 GLU 300 308 308 GLU GLU B . n B 1 301 ALA 301 309 309 ALA ALA B . n B 1 302 TRP 302 310 310 TRP TRP B . n B 1 303 PHE 303 311 311 PHE PHE B . n B 1 304 VAL 304 312 312 VAL VAL B . n B 1 305 LYS 305 313 313 LYS LYS B . n B 1 306 TYR 306 314 314 TYR TYR B . n B 1 307 LYS 307 315 315 LYS LYS B . n B 1 308 VAL 308 316 316 VAL VAL B . n B 1 309 ASP 309 317 317 ASP ASP B . n B 1 310 VAL 310 318 318 VAL VAL B . n B 1 311 VAL 311 319 319 VAL VAL B . n B 1 312 PHE 312 320 320 PHE PHE B . n B 1 313 ALA 313 321 321 ALA ALA B . n B 1 314 GLY 314 322 322 GLY GLY B . n B 1 315 HIS 315 323 323 HIS HIS B . n B 1 316 VAL 316 324 324 VAL VAL B . n B 1 317 HIS 317 325 325 HIS HIS B . n B 1 318 ALA 318 326 326 ALA ALA B . n B 1 319 TYR 319 327 327 TYR TYR B . n B 1 320 GLU 320 328 328 GLU GLU B . n B 1 321 ARG 321 329 329 ARG ARG B . n B 1 322 SER 322 330 330 SER SER B . n B 1 323 GLU 323 331 331 GLU GLU B . n B 1 324 ARG 324 332 332 ARG ARG B . n B 1 325 VAL 325 333 333 VAL VAL B . n B 1 326 SER 326 334 334 SER SER B . n B 1 327 ASN 327 335 335 ASN ASN B . n B 1 328 ILE 328 336 336 ILE ILE B . n B 1 329 ALA 329 337 337 ALA ALA B . n B 1 330 TYR 330 338 338 TYR TYR B . n B 1 331 LYS 331 339 339 LYS LYS B . n B 1 332 ILE 332 340 340 ILE ILE B . n B 1 333 THR 333 341 341 THR THR B . n B 1 334 ASN 334 342 342 ASN ASN B . n B 1 335 GLY 335 343 343 GLY GLY B . n B 1 336 LEU 336 344 344 LEU LEU B . n B 1 337 CYS 337 345 345 CYS CYS B . n B 1 338 THR 338 346 346 THR THR B . n B 1 339 PRO 339 347 347 PRO PRO B . n B 1 340 VAL 340 348 348 VAL VAL B . n B 1 341 LYS 341 349 349 LYS LYS B . n B 1 342 ASP 342 350 350 ASP ASP B . n B 1 343 GLN 343 351 351 GLN GLN B . n B 1 344 SER 344 352 352 SER SER B . n B 1 345 ALA 345 353 353 ALA ALA B . n B 1 346 PRO 346 354 354 PRO PRO B . n B 1 347 VAL 347 355 355 VAL VAL B . n B 1 348 TYR 348 356 356 TYR TYR B . n B 1 349 ILE 349 357 357 ILE ILE B . n B 1 350 THR 350 358 358 THR THR B . n B 1 351 ILE 351 359 359 ILE ILE B . n B 1 352 GLY 352 360 360 GLY GLY B . n B 1 353 ASP 353 361 361 ASP ASP B . n B 1 354 ALA 354 362 362 ALA ALA B . n B 1 355 GLY 355 363 363 GLY GLY B . n B 1 356 ASN 356 364 364 ASN ASN B . n B 1 357 TYR 357 365 365 TYR TYR B . n B 1 358 GLY 358 366 366 GLY GLY B . n B 1 359 VAL 359 367 367 VAL VAL B . n B 1 360 ILE 360 368 368 ILE ILE B . n B 1 361 ASP 361 369 369 ASP ASP B . n B 1 362 SER 362 370 370 SER SER B . n B 1 363 ASN 363 371 371 ASN ASN B . n B 1 364 MET 364 372 372 MET MET B . n B 1 365 ILE 365 373 373 ILE ILE B . n B 1 366 GLN 366 374 374 GLN GLN B . n B 1 367 PRO 367 375 375 PRO PRO B . n B 1 368 GLN 368 376 376 GLN GLN B . n B 1 369 PRO 369 377 377 PRO PRO B . n B 1 370 GLU 370 378 378 GLU GLU B . n B 1 371 TYR 371 379 379 TYR TYR B . n B 1 372 SER 372 380 380 SER SER B . n B 1 373 ALA 373 381 381 ALA ALA B . n B 1 374 PHE 374 382 382 PHE PHE B . n B 1 375 ARG 375 383 383 ARG ARG B . n B 1 376 GLU 376 384 384 GLU GLU B . n B 1 377 ALA 377 385 385 ALA ALA B . n B 1 378 SER 378 386 386 SER SER B . n B 1 379 PHE 379 387 387 PHE PHE B . n B 1 380 GLY 380 388 388 GLY GLY B . n B 1 381 HIS 381 389 389 HIS HIS B . n B 1 382 GLY 382 390 390 GLY GLY B . n B 1 383 MET 383 391 391 MET MET B . n B 1 384 PHE 384 392 392 PHE PHE B . n B 1 385 ASP 385 393 393 ASP ASP B . n B 1 386 ILE 386 394 394 ILE ILE B . n B 1 387 LYS 387 395 395 LYS LYS B . n B 1 388 ASN 388 396 396 ASN ASN B . n B 1 389 ARG 389 397 397 ARG ARG B . n B 1 390 THR 390 398 398 THR THR B . n B 1 391 HIS 391 399 399 HIS HIS B . n B 1 392 ALA 392 400 400 ALA ALA B . n B 1 393 HIS 393 401 401 HIS HIS B . n B 1 394 PHE 394 402 402 PHE PHE B . n B 1 395 SER 395 403 403 SER SER B . n B 1 396 TRP 396 404 404 TRP TRP B . n B 1 397 ASN 397 405 405 ASN ASN B . n B 1 398 ARG 398 406 406 ARG ARG B . n B 1 399 ASN 399 407 407 ASN ASN B . n B 1 400 GLN 400 408 408 GLN GLN B . n B 1 401 ASP 401 409 409 ASP ASP B . n B 1 402 GLY 402 410 410 GLY GLY B . n B 1 403 VAL 403 411 411 VAL VAL B . n B 1 404 ALA 404 412 412 ALA ALA B . n B 1 405 VAL 405 413 413 VAL VAL B . n B 1 406 GLU 406 414 414 GLU GLU B . n B 1 407 ALA 407 415 415 ALA ALA B . n B 1 408 ASP 408 416 416 ASP ASP B . n B 1 409 SER 409 417 417 SER SER B . n B 1 410 VAL 410 418 418 VAL VAL B . n B 1 411 TRP 411 419 419 TRP TRP B . n B 1 412 PHE 412 420 420 PHE PHE B . n B 1 413 PHE 413 421 421 PHE PHE B . n B 1 414 ASN 414 422 422 ASN ASN B . n B 1 415 ARG 415 423 423 ARG ARG B . n B 1 416 HIS 416 424 424 HIS HIS B . n B 1 417 TRP 417 425 425 TRP TRP B . n B 1 418 TYR 418 426 426 TYR TYR B . n B 1 419 PRO 419 427 427 PRO PRO B . n B 1 420 VAL 420 428 428 VAL VAL B . n B 1 421 ASP 421 429 429 ASP ASP B . n B 1 422 ASP 422 430 430 ASP ASP B . n B 1 423 SER 423 431 431 SER SER B . n B 1 424 THR 424 432 432 THR THR B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 FE 1 433 433 FE FE A . D 3 ZN 1 434 434 ZN ZN A . E 4 SO4 1 435 435 SO4 SO4 A . F 4 SO4 1 437 437 SO4 SO4 A . G 5 NDG 1 450 450 NDG NDG A . H 6 NAG 1 451 451 NAG NAG A . I 6 NAG 1 452 452 NAG NAG A . J 5 NDG 1 453 453 NDG NDG A . K 2 FE 1 433 433 FE FE B . L 3 ZN 1 434 434 ZN ZN B . M 4 SO4 1 435 435 SO4 SO4 B . N 4 SO4 1 437 437 SO4 SO4 B . O 6 NAG 1 450 450 NAG NAG B . P 6 NAG 1 451 451 NAG NAG B . Q 6 NAG 1 452 452 NAG NAG B . R 6 NAG 1 453 453 NAG NAG B . S 7 HOH 1 454 436 HOH WAT A . S 7 HOH 2 455 1 HOH WAT A . S 7 HOH 3 456 3 HOH WAT A . S 7 HOH 4 457 4 HOH WAT A . S 7 HOH 5 458 5 HOH WAT A . S 7 HOH 6 459 6 HOH WAT A . S 7 HOH 7 460 8 HOH WAT A . S 7 HOH 8 461 11 HOH WAT A . S 7 HOH 9 462 12 HOH WAT A . S 7 HOH 10 463 13 HOH WAT A . S 7 HOH 11 464 24 HOH WAT A . S 7 HOH 12 465 25 HOH WAT A . S 7 HOH 13 466 27 HOH WAT A . S 7 HOH 14 467 29 HOH WAT A . S 7 HOH 15 468 31 HOH WAT A . S 7 HOH 16 469 32 HOH WAT A . S 7 HOH 17 470 33 HOH WAT A . S 7 HOH 18 471 35 HOH WAT A . S 7 HOH 19 472 36 HOH WAT A . S 7 HOH 20 473 37 HOH WAT A . S 7 HOH 21 474 41 HOH WAT A . S 7 HOH 22 475 43 HOH WAT A . S 7 HOH 23 476 44 HOH WAT A . S 7 HOH 24 477 46 HOH WAT A . S 7 HOH 25 478 47 HOH WAT A . S 7 HOH 26 479 48 HOH WAT A . S 7 HOH 27 480 49 HOH WAT A . S 7 HOH 28 481 51 HOH WAT A . S 7 HOH 29 482 52 HOH WAT A . S 7 HOH 30 483 55 HOH WAT A . S 7 HOH 31 484 57 HOH WAT A . S 7 HOH 32 485 58 HOH WAT A . S 7 HOH 33 486 59 HOH WAT A . S 7 HOH 34 487 61 HOH WAT A . S 7 HOH 35 488 62 HOH WAT A . S 7 HOH 36 489 64 HOH WAT A . S 7 HOH 37 490 67 HOH WAT A . S 7 HOH 38 491 70 HOH WAT A . S 7 HOH 39 492 76 HOH WAT A . S 7 HOH 40 493 85 HOH WAT A . S 7 HOH 41 494 86 HOH WAT A . S 7 HOH 42 495 88 HOH WAT A . S 7 HOH 43 496 91 HOH WAT A . S 7 HOH 44 497 93 HOH WAT A . S 7 HOH 45 498 96 HOH WAT A . S 7 HOH 46 499 97 HOH WAT A . S 7 HOH 47 500 98 HOH WAT A . S 7 HOH 48 501 100 HOH WAT A . S 7 HOH 49 502 103 HOH WAT A . S 7 HOH 50 503 104 HOH WAT A . S 7 HOH 51 504 107 HOH WAT A . S 7 HOH 52 505 108 HOH WAT A . S 7 HOH 53 506 109 HOH WAT A . S 7 HOH 54 507 110 HOH WAT A . S 7 HOH 55 508 112 HOH WAT A . S 7 HOH 56 509 113 HOH WAT A . S 7 HOH 57 510 117 HOH WAT A . S 7 HOH 58 511 119 HOH WAT A . S 7 HOH 59 512 120 HOH WAT A . S 7 HOH 60 513 124 HOH WAT A . S 7 HOH 61 514 126 HOH WAT A . S 7 HOH 62 515 127 HOH WAT A . S 7 HOH 63 516 129 HOH WAT A . S 7 HOH 64 517 132 HOH WAT A . S 7 HOH 65 518 134 HOH WAT A . S 7 HOH 66 519 136 HOH WAT A . S 7 HOH 67 520 137 HOH WAT A . S 7 HOH 68 521 139 HOH WAT A . S 7 HOH 69 522 140 HOH WAT A . S 7 HOH 70 523 141 HOH WAT A . S 7 HOH 71 524 144 HOH WAT A . S 7 HOH 72 525 145 HOH WAT A . S 7 HOH 73 526 147 HOH WAT A . S 7 HOH 74 527 153 HOH WAT A . S 7 HOH 75 528 155 HOH WAT A . S 7 HOH 76 529 157 HOH WAT A . S 7 HOH 77 530 158 HOH WAT A . S 7 HOH 78 531 159 HOH WAT A . S 7 HOH 79 532 160 HOH WAT A . S 7 HOH 80 533 161 HOH WAT A . S 7 HOH 81 534 162 HOH WAT A . S 7 HOH 82 535 163 HOH WAT A . S 7 HOH 83 536 164 HOH WAT A . S 7 HOH 84 537 166 HOH WAT A . S 7 HOH 85 538 167 HOH WAT A . S 7 HOH 86 539 168 HOH WAT A . S 7 HOH 87 540 169 HOH WAT A . S 7 HOH 88 541 171 HOH WAT A . S 7 HOH 89 542 172 HOH WAT A . S 7 HOH 90 543 173 HOH WAT A . S 7 HOH 91 544 178 HOH WAT A . S 7 HOH 92 545 179 HOH WAT A . S 7 HOH 93 546 180 HOH WAT A . S 7 HOH 94 547 181 HOH WAT A . S 7 HOH 95 548 182 HOH WAT A . S 7 HOH 96 549 183 HOH WAT A . S 7 HOH 97 550 184 HOH WAT A . S 7 HOH 98 551 188 HOH WAT A . S 7 HOH 99 552 189 HOH WAT A . S 7 HOH 100 553 192 HOH WAT A . S 7 HOH 101 554 193 HOH WAT A . S 7 HOH 102 555 194 HOH WAT A . S 7 HOH 103 556 195 HOH WAT A . S 7 HOH 104 557 196 HOH WAT A . S 7 HOH 105 558 197 HOH WAT A . S 7 HOH 106 559 198 HOH WAT A . S 7 HOH 107 560 201 HOH WAT A . S 7 HOH 108 561 202 HOH WAT A . S 7 HOH 109 562 204 HOH WAT A . S 7 HOH 110 563 206 HOH WAT A . S 7 HOH 111 564 207 HOH WAT A . S 7 HOH 112 565 210 HOH WAT A . S 7 HOH 113 566 211 HOH WAT A . S 7 HOH 114 567 215 HOH WAT A . S 7 HOH 115 568 216 HOH WAT A . S 7 HOH 116 569 217 HOH WAT A . S 7 HOH 117 570 218 HOH WAT A . S 7 HOH 118 571 220 HOH WAT A . S 7 HOH 119 572 224 HOH WAT A . S 7 HOH 120 573 226 HOH WAT A . S 7 HOH 121 574 231 HOH WAT A . S 7 HOH 122 575 233 HOH WAT A . S 7 HOH 123 576 237 HOH WAT A . S 7 HOH 124 577 241 HOH WAT A . S 7 HOH 125 578 243 HOH WAT A . S 7 HOH 126 579 246 HOH WAT A . S 7 HOH 127 580 247 HOH WAT A . S 7 HOH 128 581 249 HOH WAT A . S 7 HOH 129 582 250 HOH WAT A . S 7 HOH 130 583 251 HOH WAT A . S 7 HOH 131 584 252 HOH WAT A . S 7 HOH 132 585 254 HOH WAT A . S 7 HOH 133 586 255 HOH WAT A . S 7 HOH 134 587 265 HOH WAT A . S 7 HOH 135 588 272 HOH WAT A . S 7 HOH 136 589 273 HOH WAT A . S 7 HOH 137 590 278 HOH WAT A . S 7 HOH 138 591 281 HOH WAT A . S 7 HOH 139 592 283 HOH WAT A . S 7 HOH 140 593 284 HOH WAT A . S 7 HOH 141 594 287 HOH WAT A . S 7 HOH 142 595 288 HOH WAT A . S 7 HOH 143 596 289 HOH WAT A . S 7 HOH 144 597 290 HOH WAT A . S 7 HOH 145 598 293 HOH WAT A . S 7 HOH 146 599 294 HOH WAT A . S 7 HOH 147 600 296 HOH WAT A . S 7 HOH 148 601 299 HOH WAT A . S 7 HOH 149 602 301 HOH WAT A . S 7 HOH 150 603 303 HOH WAT A . S 7 HOH 151 604 304 HOH WAT A . S 7 HOH 152 605 305 HOH WAT A . S 7 HOH 153 606 307 HOH WAT A . S 7 HOH 154 607 308 HOH WAT A . S 7 HOH 155 608 309 HOH WAT A . S 7 HOH 156 609 314 HOH WAT A . S 7 HOH 157 610 315 HOH WAT A . S 7 HOH 158 611 317 HOH WAT A . S 7 HOH 159 612 320 HOH WAT A . S 7 HOH 160 613 321 HOH WAT A . S 7 HOH 161 614 322 HOH WAT A . S 7 HOH 162 615 323 HOH WAT A . S 7 HOH 163 616 325 HOH WAT A . S 7 HOH 164 617 326 HOH WAT A . S 7 HOH 165 618 329 HOH WAT A . S 7 HOH 166 619 330 HOH WAT A . S 7 HOH 167 620 331 HOH WAT A . S 7 HOH 168 621 333 HOH WAT A . S 7 HOH 169 622 334 HOH WAT A . S 7 HOH 170 623 336 HOH WAT A . S 7 HOH 171 624 337 HOH WAT A . S 7 HOH 172 625 339 HOH WAT A . S 7 HOH 173 626 342 HOH WAT A . S 7 HOH 174 627 344 HOH WAT A . S 7 HOH 175 628 349 HOH WAT A . S 7 HOH 176 629 352 HOH WAT A . S 7 HOH 177 630 353 HOH WAT A . S 7 HOH 178 631 354 HOH WAT A . S 7 HOH 179 632 359 HOH WAT A . S 7 HOH 180 633 362 HOH WAT A . S 7 HOH 181 634 366 HOH WAT A . S 7 HOH 182 635 367 HOH WAT A . S 7 HOH 183 636 368 HOH WAT A . S 7 HOH 184 637 372 HOH WAT A . S 7 HOH 185 638 373 HOH WAT A . S 7 HOH 186 639 374 HOH WAT A . S 7 HOH 187 640 375 HOH WAT A . S 7 HOH 188 641 376 HOH WAT A . S 7 HOH 189 642 379 HOH WAT A . S 7 HOH 190 643 380 HOH WAT A . S 7 HOH 191 644 383 HOH WAT A . S 7 HOH 192 645 388 HOH WAT A . S 7 HOH 193 646 389 HOH WAT A . S 7 HOH 194 647 390 HOH WAT A . S 7 HOH 195 648 392 HOH WAT A . S 7 HOH 196 649 393 HOH WAT A . S 7 HOH 197 650 394 HOH WAT A . S 7 HOH 198 651 396 HOH WAT A . S 7 HOH 199 652 398 HOH WAT A . T 7 HOH 1 454 436 HOH WAT B . T 7 HOH 2 455 2 HOH WAT B . T 7 HOH 3 456 7 HOH WAT B . T 7 HOH 4 457 9 HOH WAT B . T 7 HOH 5 458 10 HOH WAT B . T 7 HOH 6 459 14 HOH WAT B . T 7 HOH 7 460 15 HOH WAT B . T 7 HOH 8 461 16 HOH WAT B . T 7 HOH 9 462 17 HOH WAT B . T 7 HOH 10 463 18 HOH WAT B . T 7 HOH 11 464 19 HOH WAT B . T 7 HOH 12 465 20 HOH WAT B . T 7 HOH 13 466 21 HOH WAT B . T 7 HOH 14 467 22 HOH WAT B . T 7 HOH 15 468 23 HOH WAT B . T 7 HOH 16 469 26 HOH WAT B . T 7 HOH 17 470 28 HOH WAT B . T 7 HOH 18 471 30 HOH WAT B . T 7 HOH 19 472 34 HOH WAT B . T 7 HOH 20 473 38 HOH WAT B . T 7 HOH 21 474 39 HOH WAT B . T 7 HOH 22 475 40 HOH WAT B . T 7 HOH 23 476 42 HOH WAT B . T 7 HOH 24 477 45 HOH WAT B . T 7 HOH 25 478 50 HOH WAT B . T 7 HOH 26 479 53 HOH WAT B . T 7 HOH 27 480 54 HOH WAT B . T 7 HOH 28 481 56 HOH WAT B . T 7 HOH 29 482 60 HOH WAT B . T 7 HOH 30 483 63 HOH WAT B . T 7 HOH 31 484 65 HOH WAT B . T 7 HOH 32 485 66 HOH WAT B . T 7 HOH 33 486 68 HOH WAT B . T 7 HOH 34 487 69 HOH WAT B . T 7 HOH 35 488 71 HOH WAT B . T 7 HOH 36 489 72 HOH WAT B . T 7 HOH 37 490 73 HOH WAT B . T 7 HOH 38 491 74 HOH WAT B . T 7 HOH 39 492 75 HOH WAT B . T 7 HOH 40 493 77 HOH WAT B . T 7 HOH 41 494 78 HOH WAT B . T 7 HOH 42 495 79 HOH WAT B . T 7 HOH 43 496 80 HOH WAT B . T 7 HOH 44 497 81 HOH WAT B . T 7 HOH 45 498 82 HOH WAT B . T 7 HOH 46 499 83 HOH WAT B . T 7 HOH 47 500 84 HOH WAT B . T 7 HOH 48 501 87 HOH WAT B . T 7 HOH 49 502 89 HOH WAT B . T 7 HOH 50 503 90 HOH WAT B . T 7 HOH 51 504 92 HOH WAT B . T 7 HOH 52 505 94 HOH WAT B . T 7 HOH 53 506 95 HOH WAT B . T 7 HOH 54 507 99 HOH WAT B . T 7 HOH 55 508 101 HOH WAT B . T 7 HOH 56 509 102 HOH WAT B . T 7 HOH 57 510 105 HOH WAT B . T 7 HOH 58 511 106 HOH WAT B . T 7 HOH 59 512 111 HOH WAT B . T 7 HOH 60 513 114 HOH WAT B . T 7 HOH 61 514 115 HOH WAT B . T 7 HOH 62 515 116 HOH WAT B . T 7 HOH 63 516 118 HOH WAT B . T 7 HOH 64 517 121 HOH WAT B . T 7 HOH 65 518 122 HOH WAT B . T 7 HOH 66 519 123 HOH WAT B . T 7 HOH 67 520 125 HOH WAT B . T 7 HOH 68 521 128 HOH WAT B . T 7 HOH 69 522 130 HOH WAT B . T 7 HOH 70 523 131 HOH WAT B . T 7 HOH 71 524 133 HOH WAT B . T 7 HOH 72 525 135 HOH WAT B . T 7 HOH 73 526 138 HOH WAT B . T 7 HOH 74 527 142 HOH WAT B . T 7 HOH 75 528 143 HOH WAT B . T 7 HOH 76 529 146 HOH WAT B . T 7 HOH 77 530 148 HOH WAT B . T 7 HOH 78 531 149 HOH WAT B . T 7 HOH 79 532 150 HOH WAT B . T 7 HOH 80 533 151 HOH WAT B . T 7 HOH 81 534 152 HOH WAT B . T 7 HOH 82 535 154 HOH WAT B . T 7 HOH 83 536 156 HOH WAT B . T 7 HOH 84 537 165 HOH WAT B . T 7 HOH 85 538 170 HOH WAT B . T 7 HOH 86 539 174 HOH WAT B . T 7 HOH 87 540 175 HOH WAT B . T 7 HOH 88 541 176 HOH WAT B . T 7 HOH 89 542 177 HOH WAT B . T 7 HOH 90 543 185 HOH WAT B . T 7 HOH 91 544 186 HOH WAT B . T 7 HOH 92 545 187 HOH WAT B . T 7 HOH 93 546 190 HOH WAT B . T 7 HOH 94 547 191 HOH WAT B . T 7 HOH 95 548 199 HOH WAT B . T 7 HOH 96 549 200 HOH WAT B . T 7 HOH 97 550 203 HOH WAT B . T 7 HOH 98 551 205 HOH WAT B . T 7 HOH 99 552 208 HOH WAT B . T 7 HOH 100 553 209 HOH WAT B . T 7 HOH 101 554 212 HOH WAT B . T 7 HOH 102 555 213 HOH WAT B . T 7 HOH 103 556 214 HOH WAT B . T 7 HOH 104 557 219 HOH WAT B . T 7 HOH 105 558 221 HOH WAT B . T 7 HOH 106 559 222 HOH WAT B . T 7 HOH 107 560 223 HOH WAT B . T 7 HOH 108 561 225 HOH WAT B . T 7 HOH 109 562 227 HOH WAT B . T 7 HOH 110 563 228 HOH WAT B . T 7 HOH 111 564 229 HOH WAT B . T 7 HOH 112 565 230 HOH WAT B . T 7 HOH 113 566 232 HOH WAT B . T 7 HOH 114 567 234 HOH WAT B . T 7 HOH 115 568 235 HOH WAT B . T 7 HOH 116 569 236 HOH WAT B . T 7 HOH 117 570 238 HOH WAT B . T 7 HOH 118 571 239 HOH WAT B . T 7 HOH 119 572 240 HOH WAT B . T 7 HOH 120 573 242 HOH WAT B . T 7 HOH 121 574 244 HOH WAT B . T 7 HOH 122 575 245 HOH WAT B . T 7 HOH 123 576 248 HOH WAT B . T 7 HOH 124 577 253 HOH WAT B . T 7 HOH 125 578 256 HOH WAT B . T 7 HOH 126 579 257 HOH WAT B . T 7 HOH 127 580 258 HOH WAT B . T 7 HOH 128 581 259 HOH WAT B . T 7 HOH 129 582 260 HOH WAT B . T 7 HOH 130 583 261 HOH WAT B . T 7 HOH 131 584 262 HOH WAT B . T 7 HOH 132 585 263 HOH WAT B . T 7 HOH 133 586 264 HOH WAT B . T 7 HOH 134 587 266 HOH WAT B . T 7 HOH 135 588 267 HOH WAT B . T 7 HOH 136 589 268 HOH WAT B . T 7 HOH 137 590 269 HOH WAT B . T 7 HOH 138 591 270 HOH WAT B . T 7 HOH 139 592 271 HOH WAT B . T 7 HOH 140 593 274 HOH WAT B . T 7 HOH 141 594 275 HOH WAT B . T 7 HOH 142 595 276 HOH WAT B . T 7 HOH 143 596 277 HOH WAT B . T 7 HOH 144 597 279 HOH WAT B . T 7 HOH 145 598 280 HOH WAT B . T 7 HOH 146 599 282 HOH WAT B . T 7 HOH 147 600 285 HOH WAT B . T 7 HOH 148 601 286 HOH WAT B . T 7 HOH 149 602 291 HOH WAT B . T 7 HOH 150 603 292 HOH WAT B . T 7 HOH 151 604 295 HOH WAT B . T 7 HOH 152 605 297 HOH WAT B . T 7 HOH 153 606 298 HOH WAT B . T 7 HOH 154 607 300 HOH WAT B . T 7 HOH 155 608 302 HOH WAT B . T 7 HOH 156 609 306 HOH WAT B . T 7 HOH 157 610 310 HOH WAT B . T 7 HOH 158 611 311 HOH WAT B . T 7 HOH 159 612 312 HOH WAT B . T 7 HOH 160 613 313 HOH WAT B . T 7 HOH 161 614 316 HOH WAT B . T 7 HOH 162 615 318 HOH WAT B . T 7 HOH 163 616 319 HOH WAT B . T 7 HOH 164 617 324 HOH WAT B . T 7 HOH 165 618 327 HOH WAT B . T 7 HOH 166 619 328 HOH WAT B . T 7 HOH 167 620 332 HOH WAT B . T 7 HOH 168 621 335 HOH WAT B . T 7 HOH 169 622 338 HOH WAT B . T 7 HOH 170 623 340 HOH WAT B . T 7 HOH 171 624 341 HOH WAT B . T 7 HOH 172 625 343 HOH WAT B . T 7 HOH 173 626 345 HOH WAT B . T 7 HOH 174 627 346 HOH WAT B . T 7 HOH 175 628 347 HOH WAT B . T 7 HOH 176 629 348 HOH WAT B . T 7 HOH 177 630 350 HOH WAT B . T 7 HOH 178 631 351 HOH WAT B . T 7 HOH 179 632 355 HOH WAT B . T 7 HOH 180 633 356 HOH WAT B . T 7 HOH 181 634 357 HOH WAT B . T 7 HOH 182 635 358 HOH WAT B . T 7 HOH 183 636 360 HOH WAT B . T 7 HOH 184 637 361 HOH WAT B . T 7 HOH 185 638 363 HOH WAT B . T 7 HOH 186 639 364 HOH WAT B . T 7 HOH 187 640 365 HOH WAT B . T 7 HOH 188 641 369 HOH WAT B . T 7 HOH 189 642 370 HOH WAT B . T 7 HOH 190 643 371 HOH WAT B . T 7 HOH 191 644 377 HOH WAT B . T 7 HOH 192 645 378 HOH WAT B . T 7 HOH 193 646 381 HOH WAT B . T 7 HOH 194 647 382 HOH WAT B . T 7 HOH 195 648 384 HOH WAT B . T 7 HOH 196 649 385 HOH WAT B . T 7 HOH 197 650 386 HOH WAT B . T 7 HOH 198 651 387 HOH WAT B . T 7 HOH 199 652 391 HOH WAT B . T 7 HOH 200 653 395 HOH WAT B . T 7 HOH 201 654 397 HOH WAT B . T 7 HOH 202 655 399 HOH WAT B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 135 A ASN 143 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 388 A ASN 396 ? ASN 'GLYCOSYLATION SITE' 3 B ASN 73 B ASN 81 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 101 B ASN 109 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 135 B ASN 143 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 388 B ASN 396 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T # _pdbx_struct_assembly_prop.biol_id 1 _pdbx_struct_assembly_prop.type 'ABSA (A^2)' _pdbx_struct_assembly_prop.value 6230 _pdbx_struct_assembly_prop.details ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD2 ? A ASP 127 ? A ASP 135 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 86.9 ? 2 OD2 ? A ASP 127 ? A ASP 135 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 OH ? A TYR 159 ? A TYR 167 ? 1_555 96.9 ? 3 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 OH ? A TYR 159 ? A TYR 167 ? 1_555 95.4 ? 4 OD2 ? A ASP 127 ? A ASP 135 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 NE2 ? A HIS 317 ? A HIS 325 ? 1_555 97.2 ? 5 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 NE2 ? A HIS 317 ? A HIS 325 ? 1_555 174.1 ? 6 OH ? A TYR 159 ? A TYR 167 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 NE2 ? A HIS 317 ? A HIS 325 ? 1_555 88.4 ? 7 OD2 ? A ASP 127 ? A ASP 135 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 127.1 ? 8 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 90.8 ? 9 OH ? A TYR 159 ? A TYR 167 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 135.9 ? 10 NE2 ? A HIS 317 ? A HIS 325 ? 1_555 FE ? C FE . ? A FE 433 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 83.4 ? 11 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 OD1 ? A ASN 193 ? A ASN 201 ? 1_555 87.8 ? 12 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 NE2 ? A HIS 278 ? A HIS 286 ? 1_555 88.7 ? 13 OD1 ? A ASN 193 ? A ASN 201 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 NE2 ? A HIS 278 ? A HIS 286 ? 1_555 90.0 ? 14 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 ND1 ? A HIS 315 ? A HIS 323 ? 1_555 173.3 ? 15 OD1 ? A ASN 193 ? A ASN 201 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 ND1 ? A HIS 315 ? A HIS 323 ? 1_555 96.1 ? 16 NE2 ? A HIS 278 ? A HIS 286 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 ND1 ? A HIS 315 ? A HIS 323 ? 1_555 85.9 ? 17 OD2 ? A ASP 156 ? A ASP 164 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 80.2 ? 18 OD1 ? A ASN 193 ? A ASN 201 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 112.4 ? 19 NE2 ? A HIS 278 ? A HIS 286 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 154.3 ? 20 ND1 ? A HIS 315 ? A HIS 323 ? 1_555 ZN ? D ZN . ? A ZN 434 ? 1_555 O ? S HOH . ? A HOH 454 ? 1_555 103.2 ? 21 OD2 ? B ASP 127 ? B ASP 135 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 78.5 ? 22 OD2 ? B ASP 127 ? B ASP 135 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 OH ? B TYR 159 ? B TYR 167 ? 1_555 99.4 ? 23 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 OH ? B TYR 159 ? B TYR 167 ? 1_555 97.1 ? 24 OD2 ? B ASP 127 ? B ASP 135 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 NE2 ? B HIS 317 ? B HIS 325 ? 1_555 105.8 ? 25 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 NE2 ? B HIS 317 ? B HIS 325 ? 1_555 173.5 ? 26 OH ? B TYR 159 ? B TYR 167 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 NE2 ? B HIS 317 ? B HIS 325 ? 1_555 87.1 ? 27 OD2 ? B ASP 127 ? B ASP 135 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 120.9 ? 28 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 85.2 ? 29 OH ? B TYR 159 ? B TYR 167 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 139.2 ? 30 NE2 ? B HIS 317 ? B HIS 325 ? 1_555 FE ? K FE . ? B FE 433 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 88.4 ? 31 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 OD1 ? B ASN 193 ? B ASN 201 ? 1_555 92.0 ? 32 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 NE2 ? B HIS 278 ? B HIS 286 ? 1_555 87.5 ? 33 OD1 ? B ASN 193 ? B ASN 201 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 NE2 ? B HIS 278 ? B HIS 286 ? 1_555 94.0 ? 34 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 ND1 ? B HIS 315 ? B HIS 323 ? 1_555 171.7 ? 35 OD1 ? B ASN 193 ? B ASN 201 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 ND1 ? B HIS 315 ? B HIS 323 ? 1_555 96.2 ? 36 NE2 ? B HIS 278 ? B HIS 286 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 ND1 ? B HIS 315 ? B HIS 323 ? 1_555 91.6 ? 37 OD2 ? B ASP 156 ? B ASP 164 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 78.8 ? 38 OD1 ? B ASN 193 ? B ASN 201 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 115.0 ? 39 NE2 ? B HIS 278 ? B HIS 286 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 148.1 ? 40 ND1 ? B HIS 315 ? B HIS 323 ? 1_555 ZN ? L ZN . ? B ZN 434 ? 1_555 O ? T HOH . ? B HOH 454 ? 1_555 97.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-10-14 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal CNS . ? package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns.csb.yale.edu/v1.1/ Fortran_77 ? 1 PDB_EXTRACT 2.000 'April. 3, 2006' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 2 CrystalClear . ? ? ? ? 'data collection' ? ? ? 3 HKL-2000 . ? ? ? ? 'data reduction' ? ? ? 4 HKL-2000 . ? ? ? ? 'data scaling' ? ? ? 5 EPMR . ? ? ? ? phasing ? ? ? 6 # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 NH2 _pdbx_validate_close_contact.auth_asym_id_1 B _pdbx_validate_close_contact.auth_comp_id_1 ARG _pdbx_validate_close_contact.auth_seq_id_1 275 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 O _pdbx_validate_close_contact.auth_asym_id_2 B _pdbx_validate_close_contact.auth_comp_id_2 LYS _pdbx_validate_close_contact.auth_seq_id_2 315 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.16 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PRO A 52 ? ? -33.33 -70.38 2 1 LYS A 63 ? ? -69.93 -91.60 3 1 ARG A 66 ? ? -54.34 106.58 4 1 PHE A 79 ? ? -114.40 -82.71 5 1 PHE A 80 ? ? -109.25 -98.70 6 1 ASN A 98 ? ? 39.27 50.66 7 1 ASN A 109 ? ? -96.18 -116.73 8 1 GLN A 138 ? ? -145.04 43.72 9 1 ASP A 164 ? ? 65.34 89.45 10 1 LEU A 165 ? ? -84.76 -78.93 11 1 ASP A 175 ? ? -12.51 90.70 12 1 ASN A 176 ? ? -59.77 -5.96 13 1 ALA A 243 ? ? 60.01 -126.96 14 1 TYR A 256 ? ? -143.48 28.42 15 1 HIS A 323 ? ? 64.96 -51.38 16 1 ALA A 326 ? ? -171.79 -169.64 17 1 ILE A 340 ? ? 71.19 -51.18 18 1 ASN A 364 ? ? 42.37 -131.12 19 1 LYS A 395 ? ? -100.57 -64.82 20 1 PRO A 427 ? ? -63.09 52.71 21 1 LYS B 63 ? ? -71.78 -83.48 22 1 ASN B 64 ? ? -59.40 107.63 23 1 PHE B 79 ? ? -100.49 -87.51 24 1 PHE B 80 ? ? -105.46 -97.72 25 1 ASN B 98 ? ? 28.61 56.66 26 1 ASN B 109 ? ? -114.64 -119.38 27 1 GLN B 138 ? ? -143.63 47.73 28 1 LYS B 155 ? ? -34.64 128.54 29 1 ASP B 164 ? ? 62.15 87.82 30 1 LEU B 165 ? ? -82.50 -79.31 31 1 ASP B 175 ? ? -11.15 90.15 32 1 SER B 189 ? ? -120.69 -55.16 33 1 ALA B 243 ? ? 58.58 -124.12 34 1 TYR B 256 ? ? -144.68 28.48 35 1 HIS B 323 ? ? 66.05 -52.42 36 1 ALA B 326 ? ? -174.54 -167.07 37 1 ILE B 340 ? ? 69.34 -50.07 38 1 ASN B 364 ? ? 39.76 -137.28 39 1 LYS B 395 ? ? -101.41 -66.06 40 1 ASN B 396 ? ? -117.74 -169.06 41 1 PRO B 427 ? ? -68.17 55.18 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 108 ? CG ? A ARG 100 CG 2 1 Y 1 A ARG 108 ? CD ? A ARG 100 CD 3 1 Y 1 A ARG 108 ? NE ? A ARG 100 NE 4 1 Y 1 A ARG 108 ? CZ ? A ARG 100 CZ 5 1 Y 1 A ARG 108 ? NH1 ? A ARG 100 NH1 6 1 Y 1 A ARG 108 ? NH2 ? A ARG 100 NH2 7 1 Y 1 B ARG 108 ? CG ? B ARG 100 CG 8 1 Y 1 B ARG 108 ? CD ? B ARG 100 CD 9 1 Y 1 B ARG 108 ? NE ? B ARG 100 NE 10 1 Y 1 B ARG 108 ? CZ ? B ARG 100 CZ 11 1 Y 1 B ARG 108 ? NH1 ? B ARG 100 NH1 12 1 Y 1 B ARG 108 ? NH2 ? B ARG 100 NH2 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'FE (III) ION' FE 3 'ZINC ION' ZN 4 'SULFATE ION' SO4 5 '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' NDG 6 N-ACETYL-D-GLUCOSAMINE NAG 7 water HOH #