data_2OZ4 # _entry.id 2OZ4 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2OZ4 RCSB RCSB041764 WWPDB D_1000041764 # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2OZ4 _pdbx_database_status.recvd_initial_deposition_date 2007-02-23 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Chen, X.' 1 'Kim, T.D.' 2 'Carman, C.V.' 3 'Mi, L.' 4 'Song, G.' 5 'Springer, T.A.' 6 # _citation.id primary _citation.title 'Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.' _citation.journal_abbrev Proc.Natl.Acad.Sci.Usa _citation.journal_volume 104 _citation.page_first 15358 _citation.page_last 15363 _citation.year 2007 _citation.journal_id_ASTM PNASA6 _citation.country US _citation.journal_id_ISSN 0027-8424 _citation.journal_id_CSD 0040 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 17881562 _citation.pdbx_database_id_DOI 10.1073/pnas.0707406104 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Chen, X.' 1 primary 'Kim, T.D.' 2 primary 'Carman, C.V.' 3 primary 'Mi, L.Z.' 4 primary 'Song, G.' 5 primary 'Springer, T.A.' 6 # _cell.entry_id 2OZ4 _cell.length_a 185.396 _cell.length_b 69.342 _cell.length_c 88.173 _cell.angle_alpha 90.00 _cell.angle_beta 112.76 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2OZ4 _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Intercellular adhesion molecule 1' 28682.322 1 ? ? ? ? 2 polymer nat 'FAB FRAGMENT LIGHT CHAIN' 23592.920 1 ? ? ? ? 3 polymer nat 'FAB FRAGMENT, HEAVY CHAIN' 22773.498 1 ? ? ? ? 4 non-polymer syn N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 5 non-polymer man ALPHA-L-FUCOSE 164.156 1 ? ? ? ? 6 non-polymer syn 'SULFATE ION' 96.063 2 ? ? ? ? 7 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 8 non-polymer syn 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL 122.143 2 ? ? ? ? 9 water nat water 18.015 276 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;VLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAV ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCS ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLE GTYLCRARSTQGEVTREVTVNVLSP ; ;VLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAV ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCS ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLE GTYLCRARSTQGEVTREVTVNVLSP ; A ? 2 'polypeptide(L)' no no ;DILLTQSPAILSVSPGERVSFSCRASQSIGTSIHWFQQRINGSPRLLIEYASESISGIPSRFSGSGSGTDFTLTINSVES EDIADYYCQQSNVWPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ;DILLTQSPAILSVSPGERVSFSCRASQSIGTSIHWFQQRINGSPRLLIEYASESISGIPSRFSGSGSGTDFTLTINSVES EDIADYYCQQSNVWPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; L ? 3 'polypeptide(L)' no no ;EVQLQQSGPELVQPGASVKISCKTSGYTFSEFTMHWVKQSHGKSLEWIGGINTINGGSSYKQSFKDKATLTVDKSSSTAY MELNSLTSEDSAVYYCATKGFAYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSL SSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR ; ;EVQLQQSGPELVQPGASVKISCKTSGYTFSEFTMHWVKQSHGKSLEWIGGINTINGGSSYKQSFKDKATLTVDKSSSTAY MELNSLTSEDSAVYYCATKGFAYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSL SSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR ; H ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 VAL n 1 2 LEU n 1 3 PRO n 1 4 ALA n 1 5 THR n 1 6 PRO n 1 7 PRO n 1 8 GLN n 1 9 LEU n 1 10 VAL n 1 11 SER n 1 12 PRO n 1 13 ARG n 1 14 VAL n 1 15 LEU n 1 16 GLU n 1 17 VAL n 1 18 ASP n 1 19 THR n 1 20 GLN n 1 21 GLY n 1 22 THR n 1 23 VAL n 1 24 VAL n 1 25 CYS n 1 26 SER n 1 27 LEU n 1 28 ASP n 1 29 GLY n 1 30 LEU n 1 31 PHE n 1 32 PRO n 1 33 VAL n 1 34 SER n 1 35 GLU n 1 36 ALA n 1 37 GLN n 1 38 VAL n 1 39 HIS n 1 40 LEU n 1 41 ALA n 1 42 LEU n 1 43 GLY n 1 44 ASP n 1 45 GLN n 1 46 ARG n 1 47 LEU n 1 48 ASN n 1 49 PRO n 1 50 THR n 1 51 VAL n 1 52 THR n 1 53 TYR n 1 54 GLY n 1 55 ASN n 1 56 ASP n 1 57 SER n 1 58 PHE n 1 59 SER n 1 60 ALA n 1 61 LYS n 1 62 ALA n 1 63 SER n 1 64 VAL n 1 65 SER n 1 66 VAL n 1 67 THR n 1 68 ALA n 1 69 GLU n 1 70 ASP n 1 71 GLU n 1 72 GLY n 1 73 THR n 1 74 GLN n 1 75 ARG n 1 76 LEU n 1 77 THR n 1 78 CYS n 1 79 ALA n 1 80 VAL n 1 81 ILE n 1 82 LEU n 1 83 GLY n 1 84 ASN n 1 85 GLN n 1 86 SER n 1 87 GLN n 1 88 GLU n 1 89 THR n 1 90 LEU n 1 91 GLN n 1 92 THR n 1 93 VAL n 1 94 THR n 1 95 ILE n 1 96 TYR n 1 97 SER n 1 98 PHE n 1 99 PRO n 1 100 ALA n 1 101 PRO n 1 102 ASN n 1 103 VAL n 1 104 ILE n 1 105 LEU n 1 106 THR n 1 107 LYS n 1 108 PRO n 1 109 GLU n 1 110 VAL n 1 111 SER n 1 112 GLU n 1 113 GLY n 1 114 THR n 1 115 GLU n 1 116 VAL n 1 117 THR n 1 118 VAL n 1 119 LYS n 1 120 CYS n 1 121 GLU n 1 122 ALA n 1 123 HIS n 1 124 PRO n 1 125 ARG n 1 126 ALA n 1 127 LYS n 1 128 VAL n 1 129 THR n 1 130 LEU n 1 131 ASN n 1 132 GLY n 1 133 VAL n 1 134 PRO n 1 135 ALA n 1 136 GLN n 1 137 PRO n 1 138 LEU n 1 139 GLY n 1 140 PRO n 1 141 ARG n 1 142 ALA n 1 143 GLN n 1 144 LEU n 1 145 LEU n 1 146 LEU n 1 147 LYS n 1 148 ALA n 1 149 THR n 1 150 PRO n 1 151 GLU n 1 152 ASP n 1 153 ASN n 1 154 GLY n 1 155 ARG n 1 156 SER n 1 157 PHE n 1 158 SER n 1 159 CYS n 1 160 SER n 1 161 ALA n 1 162 THR n 1 163 LEU n 1 164 GLU n 1 165 VAL n 1 166 ALA n 1 167 GLY n 1 168 GLN n 1 169 LEU n 1 170 ILE n 1 171 HIS n 1 172 LYS n 1 173 ASN n 1 174 GLN n 1 175 THR n 1 176 ARG n 1 177 GLU n 1 178 LEU n 1 179 ARG n 1 180 VAL n 1 181 LEU n 1 182 TYR n 1 183 GLY n 1 184 PRO n 1 185 ARG n 1 186 LEU n 1 187 ASP n 1 188 GLU n 1 189 ARG n 1 190 ASP n 1 191 CYS n 1 192 PRO n 1 193 GLY n 1 194 ASN n 1 195 TRP n 1 196 THR n 1 197 TRP n 1 198 PRO n 1 199 GLU n 1 200 ASN n 1 201 SER n 1 202 GLN n 1 203 GLN n 1 204 THR n 1 205 PRO n 1 206 MET n 1 207 CYS n 1 208 GLN n 1 209 ALA n 1 210 TRP n 1 211 GLY n 1 212 ASN n 1 213 PRO n 1 214 LEU n 1 215 PRO n 1 216 GLU n 1 217 LEU n 1 218 LYS n 1 219 CYS n 1 220 LEU n 1 221 LYS n 1 222 ASP n 1 223 GLY n 1 224 THR n 1 225 PHE n 1 226 PRO n 1 227 LEU n 1 228 PRO n 1 229 ILE n 1 230 GLY n 1 231 GLU n 1 232 SER n 1 233 VAL n 1 234 THR n 1 235 VAL n 1 236 THR n 1 237 ARG n 1 238 ASP n 1 239 LEU n 1 240 GLU n 1 241 GLY n 1 242 THR n 1 243 TYR n 1 244 LEU n 1 245 CYS n 1 246 ARG n 1 247 ALA n 1 248 ARG n 1 249 SER n 1 250 THR n 1 251 GLN n 1 252 GLY n 1 253 GLU n 1 254 VAL n 1 255 THR n 1 256 ARG n 1 257 GLU n 1 258 VAL n 1 259 THR n 1 260 VAL n 1 261 ASN n 1 262 VAL n 1 263 LEU n 1 264 SER n 1 265 PRO n 2 1 ASP n 2 2 ILE n 2 3 LEU n 2 4 LEU n 2 5 THR n 2 6 GLN n 2 7 SER n 2 8 PRO n 2 9 ALA n 2 10 ILE n 2 11 LEU n 2 12 SER n 2 13 VAL n 2 14 SER n 2 15 PRO n 2 16 GLY n 2 17 GLU n 2 18 ARG n 2 19 VAL n 2 20 SER n 2 21 PHE n 2 22 SER n 2 23 CYS n 2 24 ARG n 2 25 ALA n 2 26 SER n 2 27 GLN n 2 28 SER n 2 29 ILE n 2 30 GLY n 2 31 THR n 2 32 SER n 2 33 ILE n 2 34 HIS n 2 35 TRP n 2 36 PHE n 2 37 GLN n 2 38 GLN n 2 39 ARG n 2 40 ILE n 2 41 ASN n 2 42 GLY n 2 43 SER n 2 44 PRO n 2 45 ARG n 2 46 LEU n 2 47 LEU n 2 48 ILE n 2 49 GLU n 2 50 TYR n 2 51 ALA n 2 52 SER n 2 53 GLU n 2 54 SER n 2 55 ILE n 2 56 SER n 2 57 GLY n 2 58 ILE n 2 59 PRO n 2 60 SER n 2 61 ARG n 2 62 PHE n 2 63 SER n 2 64 GLY n 2 65 SER n 2 66 GLY n 2 67 SER n 2 68 GLY n 2 69 THR n 2 70 ASP n 2 71 PHE n 2 72 THR n 2 73 LEU n 2 74 THR n 2 75 ILE n 2 76 ASN n 2 77 SER n 2 78 VAL n 2 79 GLU n 2 80 SER n 2 81 GLU n 2 82 ASP n 2 83 ILE n 2 84 ALA n 2 85 ASP n 2 86 TYR n 2 87 TYR n 2 88 CYS n 2 89 GLN n 2 90 GLN n 2 91 SER n 2 92 ASN n 2 93 VAL n 2 94 TRP n 2 95 PRO n 2 96 PHE n 2 97 THR n 2 98 PHE n 2 99 GLY n 2 100 SER n 2 101 GLY n 2 102 THR n 2 103 LYS n 2 104 LEU n 2 105 GLU n 2 106 ILE n 2 107 LYS n 2 108 ARG n 2 109 ALA n 2 110 ASP n 2 111 ALA n 2 112 ALA n 2 113 PRO n 2 114 THR n 2 115 VAL n 2 116 SER n 2 117 ILE n 2 118 PHE n 2 119 PRO n 2 120 PRO n 2 121 SER n 2 122 SER n 2 123 GLU n 2 124 GLN n 2 125 LEU n 2 126 THR n 2 127 SER n 2 128 GLY n 2 129 GLY n 2 130 ALA n 2 131 SER n 2 132 VAL n 2 133 VAL n 2 134 CYS n 2 135 PHE n 2 136 LEU n 2 137 ASN n 2 138 ASN n 2 139 PHE n 2 140 TYR n 2 141 PRO n 2 142 LYS n 2 143 ASP n 2 144 ILE n 2 145 ASN n 2 146 VAL n 2 147 LYS n 2 148 TRP n 2 149 LYS n 2 150 ILE n 2 151 ASP n 2 152 GLY n 2 153 SER n 2 154 GLU n 2 155 ARG n 2 156 GLN n 2 157 ASN n 2 158 GLY n 2 159 VAL n 2 160 LEU n 2 161 ASN n 2 162 SER n 2 163 TRP n 2 164 THR n 2 165 ASP n 2 166 GLN n 2 167 ASP n 2 168 SER n 2 169 LYS n 2 170 ASP n 2 171 SER n 2 172 THR n 2 173 TYR n 2 174 SER n 2 175 MET n 2 176 SER n 2 177 SER n 2 178 THR n 2 179 LEU n 2 180 THR n 2 181 LEU n 2 182 THR n 2 183 LYS n 2 184 ASP n 2 185 GLU n 2 186 TYR n 2 187 GLU n 2 188 ARG n 2 189 HIS n 2 190 ASN n 2 191 SER n 2 192 TYR n 2 193 THR n 2 194 CYS n 2 195 GLU n 2 196 ALA n 2 197 THR n 2 198 HIS n 2 199 LYS n 2 200 THR n 2 201 SER n 2 202 THR n 2 203 SER n 2 204 PRO n 2 205 ILE n 2 206 VAL n 2 207 LYS n 2 208 SER n 2 209 PHE n 2 210 ASN n 2 211 ARG n 2 212 ASN n 2 213 GLU n 2 214 CYS n 3 1 GLU n 3 2 VAL n 3 3 GLN n 3 4 LEU n 3 5 GLN n 3 6 GLN n 3 7 SER n 3 8 GLY n 3 9 PRO n 3 10 GLU n 3 11 LEU n 3 12 VAL n 3 13 GLN n 3 14 PRO n 3 15 GLY n 3 16 ALA n 3 17 SER n 3 18 VAL n 3 19 LYS n 3 20 ILE n 3 21 SER n 3 22 CYS n 3 23 LYS n 3 24 THR n 3 25 SER n 3 26 GLY n 3 27 TYR n 3 28 THR n 3 29 PHE n 3 30 SER n 3 31 GLU n 3 32 PHE n 3 33 THR n 3 34 MET n 3 35 HIS n 3 36 TRP n 3 37 VAL n 3 38 LYS n 3 39 GLN n 3 40 SER n 3 41 HIS n 3 42 GLY n 3 43 LYS n 3 44 SER n 3 45 LEU n 3 46 GLU n 3 47 TRP n 3 48 ILE n 3 49 GLY n 3 50 GLY n 3 51 ILE n 3 52 ASN n 3 53 THR n 3 54 ILE n 3 55 ASN n 3 56 GLY n 3 57 GLY n 3 58 SER n 3 59 SER n 3 60 TYR n 3 61 LYS n 3 62 GLN n 3 63 SER n 3 64 PHE n 3 65 LYS n 3 66 ASP n 3 67 LYS n 3 68 ALA n 3 69 THR n 3 70 LEU n 3 71 THR n 3 72 VAL n 3 73 ASP n 3 74 LYS n 3 75 SER n 3 76 SER n 3 77 SER n 3 78 THR n 3 79 ALA n 3 80 TYR n 3 81 MET n 3 82 GLU n 3 83 LEU n 3 84 ASN n 3 85 SER n 3 86 LEU n 3 87 THR n 3 88 SER n 3 89 GLU n 3 90 ASP n 3 91 SER n 3 92 ALA n 3 93 VAL n 3 94 TYR n 3 95 TYR n 3 96 CYS n 3 97 ALA n 3 98 THR n 3 99 LYS n 3 100 GLY n 3 101 PHE n 3 102 ALA n 3 103 TYR n 3 104 TRP n 3 105 GLY n 3 106 GLN n 3 107 GLY n 3 108 THR n 3 109 LEU n 3 110 VAL n 3 111 THR n 3 112 VAL n 3 113 SER n 3 114 ALA n 3 115 ALA n 3 116 LYS n 3 117 THR n 3 118 THR n 3 119 PRO n 3 120 PRO n 3 121 SER n 3 122 VAL n 3 123 TYR n 3 124 PRO n 3 125 LEU n 3 126 ALA n 3 127 PRO n 3 128 GLY n 3 129 SER n 3 130 ALA n 3 131 ALA n 3 132 GLN n 3 133 THR n 3 134 ASN n 3 135 SER n 3 136 MET n 3 137 VAL n 3 138 THR n 3 139 LEU n 3 140 GLY n 3 141 CYS n 3 142 LEU n 3 143 VAL n 3 144 LYS n 3 145 GLY n 3 146 TYR n 3 147 PHE n 3 148 PRO n 3 149 GLU n 3 150 PRO n 3 151 VAL n 3 152 THR n 3 153 VAL n 3 154 THR n 3 155 TRP n 3 156 ASN n 3 157 SER n 3 158 GLY n 3 159 SER n 3 160 LEU n 3 161 SER n 3 162 SER n 3 163 GLY n 3 164 VAL n 3 165 HIS n 3 166 THR n 3 167 PHE n 3 168 PRO n 3 169 ALA n 3 170 VAL n 3 171 LEU n 3 172 GLN n 3 173 SER n 3 174 ASP n 3 175 LEU n 3 176 TYR n 3 177 THR n 3 178 LEU n 3 179 SER n 3 180 SER n 3 181 SER n 3 182 VAL n 3 183 THR n 3 184 VAL n 3 185 PRO n 3 186 SER n 3 187 SER n 3 188 THR n 3 189 TRP n 3 190 PRO n 3 191 SER n 3 192 GLU n 3 193 THR n 3 194 VAL n 3 195 THR n 3 196 CYS n 3 197 ASN n 3 198 VAL n 3 199 ALA n 3 200 HIS n 3 201 PRO n 3 202 ALA n 3 203 SER n 3 204 SER n 3 205 THR n 3 206 LYS n 3 207 VAL n 3 208 ASP n 3 209 LYS n 3 210 LYS n 3 211 ILE n 3 212 VAL n 3 213 PRO n 3 214 ARG n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus Homo _entity_src_gen.pdbx_gene_src_gene ICAM1 _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'Chinese hamster' _entity_src_gen.pdbx_host_org_scientific_name 'Cricetulus griseus' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 10029 _entity_src_gen.host_org_genus Cricetulus _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'CHINESE HAMSTER CHO.LEC3.2.8.1' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type PLASMID _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # loop_ _entity_src_nat.entity_id _entity_src_nat.pdbx_src_id _entity_src_nat.pdbx_alt_source_flag _entity_src_nat.pdbx_beg_seq_num _entity_src_nat.pdbx_end_seq_num _entity_src_nat.common_name _entity_src_nat.pdbx_organism_scientific _entity_src_nat.pdbx_ncbi_taxonomy_id _entity_src_nat.genus _entity_src_nat.species _entity_src_nat.strain _entity_src_nat.tissue _entity_src_nat.tissue_fraction _entity_src_nat.pdbx_secretion _entity_src_nat.pdbx_fragment _entity_src_nat.pdbx_variant _entity_src_nat.pdbx_cell_line _entity_src_nat.pdbx_atcc _entity_src_nat.pdbx_cellular_location _entity_src_nat.pdbx_organ _entity_src_nat.pdbx_organelle _entity_src_nat.pdbx_cell _entity_src_nat.pdbx_plasmid_name _entity_src_nat.pdbx_plasmid_details _entity_src_nat.details 2 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP Q5NKV7_HUMAN Q5NKV7 1 ;VLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAV ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCS ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLE GTYLCRARSTQGEVTREVTVNVLSP ; 209 ? 2 UNP Q58EU4_MOUSE Q58EU4 2 ? ? ? 3 UNP HVM13_MOUSE P01757 3 ? ? ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2OZ4 A 1 ? 265 ? Q5NKV7 209 ? 473 ? 186 450 2 2 2OZ4 L 18 ? 214 ? Q58EU4 42 ? 238 ? 18 214 3 3 2OZ4 H 1 ? 113 ? P01757 1 ? 116 ? 1 113 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TRS non-polymer . 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL 'TRIS BUFFER' 'C4 H12 N O3 1' 122.143 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2OZ4 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.49 _exptl_crystal.density_percent_sol 64.78 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7.5 _exptl_crystal_grow.pdbx_details '1.5M LITHIUM SULFATE, 0.1M HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315' _diffrn_detector.pdbx_collection_date 2006-01-01 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Rosenbaum-Rock high-resolution double-crystal monochromator' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.97949 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'APS BEAMLINE 19-ID' _diffrn_source.pdbx_synchrotron_site APS _diffrn_source.pdbx_synchrotron_beamline 19-ID _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.97949 # _reflns.entry_id 2OZ4 _reflns.observed_criterion_sigma_I 0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 30 _reflns.d_resolution_high 2.70 _reflns.number_obs 26015 _reflns.number_all 26015 _reflns.percent_possible_obs 90.6 _reflns.pdbx_Rmerge_I_obs 0.087 _reflns.pdbx_Rsym_value 0.087 _reflns.pdbx_netI_over_sigmaI 11.1 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.70 _reflns_shell.d_res_low 2.80 _reflns_shell.percent_possible_all 58.1 _reflns_shell.Rmerge_I_obs 0.543 _reflns_shell.pdbx_Rsym_value 0.543 _reflns_shell.meanI_over_sigI_obs 1.2 _reflns_shell.pdbx_redundancy 2.7 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2OZ4 _refine.ls_number_reflns_obs 23400 _refine.ls_number_reflns_all 25959 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 28.50 _refine.ls_d_res_high 2.70 _refine.ls_percent_reflns_obs 100.0 _refine.ls_R_factor_obs 0.209 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.204 _refine.ls_R_factor_R_free 0.253 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 9.900 _refine.ls_number_reflns_R_free 2559 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.950 _refine.correlation_coeff_Fo_to_Fc_free 0.923 _refine.B_iso_mean 63.34 _refine.aniso_B[1][1] -5.52000 _refine.aniso_B[2][2] 6.95000 _refine.aniso_B[3][3] -4.62000 _refine.aniso_B[1][2] 0.00000 _refine.aniso_B[1][3] -4.12000 _refine.aniso_B[2][3] 0.00000 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'pdb entries 1F11, 1P53' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model overall _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 1.353 _refine.pdbx_overall_ESU_R_Free 0.346 _refine.overall_SU_ML 0.288 _refine.overall_SU_B 26.501 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_TLS_residual_ADP_flag 'LIKELY RESIDUAL' _refine.pdbx_diffrn_id 1 _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 2OZ4 _refine_analyze.Luzzati_coordinate_error_obs 0.455 _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 5234 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 80 _refine_hist.number_atoms_solvent 276 _refine_hist.number_atoms_total 5590 _refine_hist.d_res_high 2.70 _refine_hist.d_res_low 28.50 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.005 0.022 ? 5449 'X-RAY DIFFRACTION' ? r_bond_other_d 0.001 0.020 ? 3605 'X-RAY DIFFRACTION' ? r_angle_refined_deg 0.903 1.974 ? 7446 'X-RAY DIFFRACTION' ? r_angle_other_deg 0.656 3.000 ? 8848 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 4.960 5.000 ? 685 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 30.831 24.720 ? 214 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 10.599 15.000 ? 863 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 12.788 15.000 ? 25 'X-RAY DIFFRACTION' ? r_chiral_restr 0.091 0.200 ? 867 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.002 0.020 ? 6001 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.001 0.020 ? 1008 'X-RAY DIFFRACTION' ? r_nbd_refined 0.149 0.200 ? 864 'X-RAY DIFFRACTION' ? r_nbd_other 0.164 0.200 ? 3592 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.163 0.200 ? 2617 'X-RAY DIFFRACTION' ? r_nbtor_other 0.077 0.200 ? 2975 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.091 0.200 ? 272 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined 0.090 0.200 ? 1 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.093 0.200 ? 16 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other 0.153 0.200 ? 45 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.088 0.200 ? 15 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined 0.066 0.200 ? 2 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.627 3.000 ? 4460 'X-RAY DIFFRACTION' ? r_mcbond_other 0.016 3.000 ? 1373 'X-RAY DIFFRACTION' ? r_mcangle_it 0.897 18.000 ? 5624 'X-RAY DIFFRACTION' ? r_scbond_it 0.490 3.000 ? 2333 'X-RAY DIFFRACTION' ? r_scangle_it 0.865 18.000 ? 1822 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.70 _refine_ls_shell.d_res_low 2.77 _refine_ls_shell.number_reflns_R_work 1090 _refine_ls_shell.R_factor_R_work 0.4530 _refine_ls_shell.percent_reflns_obs 100.00 _refine_ls_shell.R_factor_R_free 0.4840 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 103 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 2OZ4 _struct.title 'Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization' _struct.pdbx_descriptor ;Intercellular adhesion molecule 1, Antibody CA 7; CHAIN L; FAB FRAGMENT LIGHT CHAIN;, Antibody CA 7; CHAIN H; FAB FRAGMENT, HEAVY CHAIN ; _struct.pdbx_model_details ? _struct.pdbx_CASP_flag N _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2OZ4 _struct_keywords.pdbx_keywords 'CELL ADHESION' _struct_keywords.text 'IGSF DOMAIN, STRUCTURAL PLASTICITY, CELL-SURFACE DIMERIZATION, CELL ADHESION' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 4 ? G N N 4 ? H N N 6 ? I N N 6 ? J N N 7 ? K N N 7 ? L N N 8 ? M N N 8 ? N N N 9 ? O N N 9 ? P N N 9 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 PRO A 32 ? ALA A 36 ? PRO A 217 ALA A 221 5 ? 5 HELX_P HELX_P2 2 THR A 67 ? GLU A 71 ? THR A 252 GLU A 256 5 ? 5 HELX_P HELX_P3 3 THR A 149 ? ASN A 153 ? THR A 334 ASN A 338 5 ? 5 HELX_P HELX_P4 4 ASP A 187 ? CYS A 191 ? ASP A 372 CYS A 376 5 ? 5 HELX_P HELX_P5 5 THR A 236 ? GLU A 240 ? THR A 421 GLU A 425 5 ? 5 HELX_P HELX_P6 6 GLU B 79 ? ILE B 83 ? GLU L 79 ILE L 83 5 ? 5 HELX_P HELX_P7 7 SER B 121 ? GLY B 128 ? SER L 121 GLY L 128 1 ? 8 HELX_P HELX_P8 8 LYS B 183 ? GLU B 187 ? LYS L 183 GLU L 187 1 ? 5 HELX_P HELX_P9 9 GLN C 62 ? LYS C 65 ? GLN H 62 LYS H 65 5 ? 4 HELX_P HELX_P10 10 THR C 87 ? SER C 91 ? THR H 87 SER H 91 5 ? 5 HELX_P HELX_P11 11 PRO C 185 ? TRP C 189 ? PRO H 185 TRP H 189 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 25 SG ? ? ? 1_555 A CYS 78 SG ? ? A CYS 210 A CYS 263 1_555 ? ? ? ? ? ? ? 2.030 ? disulf2 disulf ? ? A CYS 120 SG ? ? ? 1_555 A CYS 159 SG ? ? A CYS 305 A CYS 344 1_555 ? ? ? ? ? ? ? 2.033 ? disulf3 disulf ? ? A CYS 191 SG ? ? ? 1_555 A CYS 207 SG ? ? A CYS 376 A CYS 392 1_555 ? ? ? ? ? ? ? 2.036 ? disulf4 disulf ? ? A CYS 219 SG ? ? ? 1_555 A CYS 245 SG ? ? A CYS 404 A CYS 430 1_555 ? ? ? ? ? ? ? 2.034 ? disulf5 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 88 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.052 ? disulf6 disulf ? ? B CYS 134 SG ? ? ? 1_555 B CYS 194 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.036 ? disulf7 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 96 1_555 ? ? ? ? ? ? ? 2.049 ? disulf8 disulf ? ? C CYS 141 SG ? ? ? 1_555 C CYS 196 SG ? ? H CYS 141 H CYS 196 1_555 ? ? ? ? ? ? ? 2.035 ? covale1 covale ? ? A ASN 84 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 269 A NAG 1269 1_555 ? ? ? ? ? ? ? 1.452 ? covale2 covale ? ? A ASN 173 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 358 A NAG 1358 1_555 ? ? ? ? ? ? ? 1.446 ? covale3 covale ? ? A ASN 55 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 240 A NAG 1240 1_555 ? ? ? ? ? ? ? 1.446 ? covale4 covale ? ? D NAG . O6 ? ? ? 1_555 E FUC . C1 ? ? A NAG 1240 A FUC 1241 1_555 ? ? ? ? ? ? ? 1.444 ? metalc1 metalc ? ? B ASP 1 N ? ? ? 1_555 J ZN . ZN ? ? L ASP 1 L ZN 2001 1_555 ? ? ? ? ? ? ? 2.124 ? metalc2 metalc ? ? B ASP 1 O ? ? ? 1_555 J ZN . ZN ? ? L ASP 1 L ZN 2001 1_555 ? ? ? ? ? ? ? 2.190 ? metalc3 metalc ? ? B GLU 185 OE1 ? ? ? 1_555 K ZN . ZN ? ? L GLU 185 L ZN 2002 1_555 ? ? ? ? ? ? ? 2.209 ? metalc4 metalc ? ? K ZN . ZN ? ? ? 1_555 O HOH . O ? ? L ZN 2002 L HOH 3082 1_555 ? ? ? ? ? ? ? 1.930 ? metalc5 metalc ? ? K ZN . ZN ? ? ? 1_555 O HOH . O ? ? L ZN 2002 L HOH 3081 1_555 ? ? ? ? ? ? ? 2.308 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 31 A . ? PHE 216 A PRO 32 A ? PRO 217 A 1 -4.56 2 VAL 133 A . ? VAL 318 A PRO 134 A ? PRO 319 A 1 1.24 3 ASN 212 A . ? ASN 397 A PRO 213 A ? PRO 398 A 1 1.44 4 SER 7 B . ? SER 7 L PRO 8 B ? PRO 8 L 1 -4.42 5 TRP 94 B . ? TRP 94 L PRO 95 B ? PRO 95 L 1 2.95 6 TYR 140 B . ? TYR 140 L PRO 141 B ? PRO 141 L 1 4.05 7 PHE 147 C . ? PHE 147 H PRO 148 C ? PRO 148 H 1 -3.25 8 GLU 149 C . ? GLU 149 H PRO 150 C ? PRO 150 H 1 -6.73 9 TRP 189 C . ? TRP 189 H PRO 190 C ? PRO 190 H 1 1.46 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 5 ? C ? 3 ? D ? 3 ? E ? 4 ? F ? 3 ? G ? 5 ? H ? 2 ? I ? 4 ? J ? 6 ? K ? 4 ? L ? 4 ? M ? 4 ? N ? 4 ? O ? 6 ? P ? 4 ? Q ? 4 ? R ? 4 ? S ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel E 1 2 ? parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? parallel F 2 3 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? anti-parallel H 1 2 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel K 1 2 ? parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel O 1 2 ? parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel O 4 5 ? anti-parallel O 5 6 ? anti-parallel P 1 2 ? parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel Q 1 2 ? anti-parallel Q 2 3 ? anti-parallel Q 3 4 ? anti-parallel R 1 2 ? anti-parallel R 2 3 ? anti-parallel R 3 4 ? anti-parallel S 1 2 ? anti-parallel S 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLN A 8 ? VAL A 10 ? GLN A 193 VAL A 195 A 2 THR A 19 ? ASP A 28 ? THR A 204 ASP A 213 A 3 SER A 57 ? VAL A 66 ? SER A 242 VAL A 251 A 4 THR A 50 ? TYR A 53 ? THR A 235 TYR A 238 B 1 VAL A 14 ? GLU A 16 ? VAL A 199 GLU A 201 B 2 GLN A 85 ? TYR A 96 ? GLN A 270 TYR A 281 B 3 GLY A 72 ? LEU A 82 ? GLY A 257 LEU A 267 B 4 GLN A 37 ? LEU A 42 ? GLN A 222 LEU A 227 B 5 GLN A 45 ? ARG A 46 ? GLN A 230 ARG A 231 C 1 ASN A 102 ? LEU A 105 ? ASN A 287 LEU A 290 C 2 GLU A 115 ? GLU A 121 ? GLU A 300 GLU A 306 C 3 ARG A 141 ? ALA A 142 ? ARG A 326 ALA A 327 D 1 ASN A 102 ? LEU A 105 ? ASN A 287 LEU A 290 D 2 GLU A 115 ? GLU A 121 ? GLU A 300 GLU A 306 D 3 LEU A 145 ? LYS A 147 ? LEU A 330 LYS A 332 E 1 GLU A 109 ? SER A 111 ? GLU A 294 SER A 296 E 2 LEU A 169 ? ARG A 185 ? LEU A 354 ARG A 370 E 3 ARG A 155 ? GLU A 164 ? ARG A 340 GLU A 349 E 4 LYS A 127 ? LEU A 130 ? LYS A 312 LEU A 315 F 1 GLU A 109 ? SER A 111 ? GLU A 294 SER A 296 F 2 LEU A 169 ? ARG A 185 ? LEU A 354 ARG A 370 F 3 TRP A 210 ? ASN A 212 ? TRP A 395 ASN A 397 G 1 ASN A 194 ? PRO A 198 ? ASN A 379 PRO A 383 G 2 GLY A 252 ? LEU A 263 ? GLY A 437 LEU A 448 G 3 GLY A 241 ? SER A 249 ? GLY A 426 SER A 434 G 4 GLU A 216 ? LYS A 221 ? GLU A 401 LYS A 406 G 5 PHE A 225 ? PRO A 226 ? PHE A 410 PRO A 411 H 1 GLN A 202 ? GLN A 203 ? GLN A 387 GLN A 388 H 2 VAL A 233 ? THR A 234 ? VAL A 418 THR A 419 I 1 LEU B 4 ? SER B 7 ? LEU L 4 SER L 7 I 2 VAL B 19 ? ALA B 25 ? VAL L 19 ALA L 25 I 3 ASP B 70 ? ILE B 75 ? ASP L 70 ILE L 75 I 4 PHE B 62 ? SER B 67 ? PHE L 62 SER L 67 J 1 ILE B 10 ? VAL B 13 ? ILE L 10 VAL L 13 J 2 THR B 102 ? ILE B 106 ? THR L 102 ILE L 106 J 3 ALA B 84 ? GLN B 90 ? ALA L 84 GLN L 90 J 4 ILE B 33 ? GLN B 38 ? ILE L 33 GLN L 38 J 5 ARG B 45 ? GLU B 49 ? ARG L 45 GLU L 49 J 6 GLU B 53 ? SER B 54 ? GLU L 53 SER L 54 K 1 ILE B 10 ? VAL B 13 ? ILE L 10 VAL L 13 K 2 THR B 102 ? ILE B 106 ? THR L 102 ILE L 106 K 3 ALA B 84 ? GLN B 90 ? ALA L 84 GLN L 90 K 4 THR B 97 ? PHE B 98 ? THR L 97 PHE L 98 L 1 THR B 114 ? PHE B 118 ? THR L 114 PHE L 118 L 2 GLY B 129 ? PHE B 139 ? GLY L 129 PHE L 139 L 3 TYR B 173 ? THR B 182 ? TYR L 173 THR L 182 L 4 VAL B 159 ? TRP B 163 ? VAL L 159 TRP L 163 M 1 SER B 153 ? GLU B 154 ? SER L 153 GLU L 154 M 2 ASN B 145 ? ILE B 150 ? ASN L 145 ILE L 150 M 3 SER B 191 ? THR B 197 ? SER L 191 THR L 197 M 4 ILE B 205 ? ASN B 210 ? ILE L 205 ASN L 210 N 1 GLN C 3 ? GLN C 6 ? GLN H 3 GLN H 6 N 2 VAL C 18 ? SER C 25 ? VAL H 18 SER H 25 N 3 THR C 78 ? LEU C 83 ? THR H 78 LEU H 83 N 4 ALA C 68 ? ASP C 73 ? ALA H 68 ASP H 73 O 1 GLU C 10 ? VAL C 12 ? GLU H 10 VAL H 12 O 2 THR C 108 ? VAL C 112 ? THR H 108 VAL H 112 O 3 ALA C 92 ? THR C 98 ? ALA H 92 THR H 98 O 4 MET C 34 ? GLN C 39 ? MET H 34 GLN H 39 O 5 LEU C 45 ? ILE C 51 ? LEU H 45 ILE H 51 O 6 SER C 58 ? TYR C 60 ? SER H 58 TYR H 60 P 1 GLU C 10 ? VAL C 12 ? GLU H 10 VAL H 12 P 2 THR C 108 ? VAL C 112 ? THR H 108 VAL H 112 P 3 ALA C 92 ? THR C 98 ? ALA H 92 THR H 98 P 4 TYR C 103 ? TRP C 104 ? TYR H 103 TRP H 104 Q 1 SER C 121 ? LEU C 125 ? SER H 121 LEU H 125 Q 2 THR C 138 ? TYR C 146 ? THR H 138 TYR H 146 Q 3 TYR C 176 ? THR C 183 ? TYR H 176 THR H 183 Q 4 VAL C 164 ? THR C 166 ? VAL H 164 THR H 166 R 1 SER C 121 ? LEU C 125 ? SER H 121 LEU H 125 R 2 THR C 138 ? TYR C 146 ? THR H 138 TYR H 146 R 3 TYR C 176 ? THR C 183 ? TYR H 176 THR H 183 R 4 VAL C 170 ? LEU C 171 ? VAL H 170 LEU H 171 S 1 THR C 152 ? TRP C 155 ? THR H 152 TRP H 155 S 2 THR C 195 ? HIS C 200 ? THR H 195 HIS H 200 S 3 THR C 205 ? LYS C 210 ? THR H 205 LYS H 210 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 10 ? N VAL A 195 O VAL A 24 ? O VAL A 209 A 2 3 N CYS A 25 ? N CYS A 210 O ALA A 60 ? O ALA A 245 A 3 4 O SER A 59 ? O SER A 244 N THR A 52 ? N THR A 237 B 1 2 N LEU A 15 ? N LEU A 200 O THR A 94 ? O THR A 279 B 2 3 O ILE A 95 ? O ILE A 280 N GLY A 72 ? N GLY A 257 B 3 4 O THR A 77 ? O THR A 262 N ALA A 41 ? N ALA A 226 B 4 5 N LEU A 42 ? N LEU A 227 O GLN A 45 ? O GLN A 230 C 1 2 N ASN A 102 ? N ASN A 287 O GLU A 121 ? O GLU A 306 C 2 3 N CYS A 120 ? N CYS A 305 O ALA A 142 ? O ALA A 327 D 1 2 N ASN A 102 ? N ASN A 287 O GLU A 121 ? O GLU A 306 D 2 3 N VAL A 116 ? N VAL A 301 O LEU A 146 ? O LEU A 331 E 1 2 N VAL A 110 ? N VAL A 295 O LEU A 181 ? O LEU A 366 E 2 3 O LYS A 172 ? O LYS A 357 N ALA A 161 ? N ALA A 346 E 3 4 O SER A 160 ? O SER A 345 N THR A 129 ? N THR A 314 F 1 2 N VAL A 110 ? N VAL A 295 O LEU A 181 ? O LEU A 366 F 2 3 N ARG A 185 ? N ARG A 370 O TRP A 210 ? O TRP A 395 G 1 2 N TRP A 195 ? N TRP A 380 O THR A 259 ? O THR A 444 G 2 3 O VAL A 258 ? O VAL A 443 N TYR A 243 ? N TYR A 428 G 3 4 O ARG A 248 ? O ARG A 433 N GLU A 216 ? N GLU A 401 G 4 5 N LYS A 221 ? N LYS A 406 O PHE A 225 ? O PHE A 410 H 1 2 N GLN A 203 ? N GLN A 388 O VAL A 233 ? O VAL A 418 I 1 2 N THR B 5 ? N THR L 5 O ARG B 24 ? O ARG L 24 I 2 3 N PHE B 21 ? N PHE L 21 O LEU B 73 ? O LEU L 73 I 3 4 O THR B 74 ? O THR L 74 N SER B 63 ? N SER L 63 J 1 2 N LEU B 11 ? N LEU L 11 O LYS B 103 ? O LYS L 103 J 2 3 O THR B 102 ? O THR L 102 N TYR B 86 ? N TYR L 86 J 3 4 O ASP B 85 ? O ASP L 85 N GLN B 38 ? N GLN L 38 J 4 5 N TRP B 35 ? N TRP L 35 O LEU B 47 ? O LEU L 47 J 5 6 N GLU B 49 ? N GLU L 49 O GLU B 53 ? O GLU L 53 K 1 2 N LEU B 11 ? N LEU L 11 O LYS B 103 ? O LYS L 103 K 2 3 O THR B 102 ? O THR L 102 N TYR B 86 ? N TYR L 86 K 3 4 N GLN B 90 ? N GLN L 90 O THR B 97 ? O THR L 97 L 1 2 N SER B 116 ? N SER L 116 O PHE B 135 ? O PHE L 135 L 2 3 N VAL B 132 ? N VAL L 132 O LEU B 179 ? O LEU L 179 L 3 4 O THR B 178 ? O THR L 178 N LEU B 160 ? N LEU L 160 M 1 2 O SER B 153 ? O SER L 153 N ILE B 150 ? N ILE L 150 M 2 3 N LYS B 149 ? N LYS L 149 O THR B 193 ? O THR L 193 M 3 4 N ALA B 196 ? N ALA L 196 O ILE B 205 ? O ILE L 205 N 1 2 N GLN C 5 ? N GLN H 5 O LYS C 23 ? O LYS H 23 N 2 3 N VAL C 18 ? N VAL H 18 O LEU C 83 ? O LEU H 83 N 3 4 O THR C 78 ? O THR H 78 N ASP C 73 ? N ASP H 73 O 1 2 N VAL C 12 ? N VAL H 12 O THR C 111 ? O THR H 111 O 2 3 O VAL C 110 ? O VAL H 110 N ALA C 92 ? N ALA H 92 O 3 4 O TYR C 95 ? O TYR H 95 N VAL C 37 ? N VAL H 37 O 4 5 N LYS C 38 ? N LYS H 38 O GLU C 46 ? O GLU H 46 O 5 6 N GLY C 50 ? N GLY H 50 O SER C 59 ? O SER H 59 P 1 2 N VAL C 12 ? N VAL H 12 O THR C 111 ? O THR H 111 P 2 3 O VAL C 110 ? O VAL H 110 N ALA C 92 ? N ALA H 92 P 3 4 N THR C 98 ? N THR H 98 O TYR C 103 ? O TYR H 103 Q 1 2 N TYR C 123 ? N TYR H 123 O LEU C 142 ? O LEU H 142 Q 2 3 N TYR C 146 ? N TYR H 146 O TYR C 176 ? O TYR H 176 Q 3 4 O SER C 181 ? O SER H 181 N HIS C 165 ? N HIS H 165 R 1 2 N TYR C 123 ? N TYR H 123 O LEU C 142 ? O LEU H 142 R 2 3 N TYR C 146 ? N TYR H 146 O TYR C 176 ? O TYR H 176 R 3 4 O THR C 177 ? O THR H 177 N VAL C 170 ? N VAL H 170 S 1 2 N THR C 154 ? N THR H 154 O ASN C 197 ? O ASN H 197 S 2 3 N CYS C 196 ? N CYS H 196 O LYS C 209 ? O LYS H 209 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 1240' AC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE FUC A 1241' AC3 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 1269' AC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 1358' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 A 2000' AC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 L 2000' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN L 2001' AC8 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE ZN L 2002' AC9 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE TRS L 2003' BC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE TRS L 2004' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 ASN A 55 ? ASN A 240 . ? 1_555 ? 2 AC1 5 THR A 196 ? THR A 381 . ? 4_446 ? 3 AC1 5 FUC E . ? FUC A 1241 . ? 1_555 ? 4 AC1 5 HOH N . ? HOH A 3018 . ? 1_555 ? 5 AC1 5 GLN C 62 ? GLN H 62 . ? 4_446 ? 6 AC2 6 GLN A 203 ? GLN A 388 . ? 4_446 ? 7 AC2 6 NAG D . ? NAG A 1240 . ? 1_555 ? 8 AC2 6 HOH N . ? HOH A 3086 . ? 1_555 ? 9 AC2 6 TYR C 60 ? TYR H 60 . ? 4_446 ? 10 AC2 6 GLN C 62 ? GLN H 62 . ? 4_446 ? 11 AC2 6 PRO B 95 ? PRO L 95 . ? 4_446 ? 12 AC3 2 ASN A 84 ? ASN A 269 . ? 1_555 ? 13 AC3 2 GLU A 164 ? GLU A 349 . ? 4_445 ? 14 AC4 6 SER A 158 ? SER A 343 . ? 1_555 ? 15 AC4 6 ASN A 173 ? ASN A 358 . ? 1_555 ? 16 AC4 6 THR A 175 ? THR A 360 . ? 1_555 ? 17 AC4 6 LYS B 107 ? LYS L 107 . ? 4_446 ? 18 AC4 6 ARG B 108 ? ARG L 108 . ? 4_446 ? 19 AC4 6 ALA B 109 ? ALA L 109 . ? 4_446 ? 20 AC5 6 LYS A 218 ? LYS A 403 . ? 2_557 ? 21 AC5 6 ARG A 246 ? ARG A 431 . ? 2_557 ? 22 AC5 6 ARG A 248 ? ARG A 433 . ? 2_557 ? 23 AC5 6 ARG A 248 ? ARG A 433 . ? 1_555 ? 24 AC5 6 HOH N . ? HOH A 3126 . ? 2_557 ? 25 AC5 6 HOH N . ? HOH A 3126 . ? 1_555 ? 26 AC6 6 ARG B 39 ? ARG L 39 . ? 1_555 ? 27 AC6 6 ARG B 45 ? ARG L 45 . ? 1_555 ? 28 AC6 6 PRO B 59 ? PRO L 59 . ? 1_555 ? 29 AC6 6 ARG B 61 ? ARG L 61 . ? 1_555 ? 30 AC6 6 HOH O . ? HOH L 3026 . ? 1_555 ? 31 AC6 6 HOH O . ? HOH L 3070 . ? 1_555 ? 32 AC7 4 ASP A 28 ? ASP A 213 . ? 4_456 ? 33 AC7 4 ASP A 56 ? ASP A 241 . ? 4_456 ? 34 AC7 4 HOH N . ? HOH A 3103 . ? 4_456 ? 35 AC7 4 ASP B 1 ? ASP L 1 . ? 1_555 ? 36 AC8 8 GLU B 185 ? GLU L 185 . ? 2_456 ? 37 AC8 8 GLU B 185 ? GLU L 185 . ? 1_555 ? 38 AC8 8 HIS B 189 ? HIS L 189 . ? 2_456 ? 39 AC8 8 HIS B 189 ? HIS L 189 . ? 1_555 ? 40 AC8 8 HOH O . ? HOH L 3081 . ? 1_555 ? 41 AC8 8 HOH O . ? HOH L 3081 . ? 2_456 ? 42 AC8 8 HOH O . ? HOH L 3082 . ? 2_456 ? 43 AC8 8 HOH O . ? HOH L 3082 . ? 1_555 ? 44 AC9 5 ASP C 208 ? ASP H 208 . ? 4_456 ? 45 AC9 5 PRO B 59 ? PRO L 59 . ? 1_555 ? 46 AC9 5 SER B 60 ? SER L 60 . ? 1_555 ? 47 AC9 5 HOH O . ? HOH L 3022 . ? 1_555 ? 48 AC9 5 HOH O . ? HOH L 3036 . ? 1_555 ? 49 BC1 6 LYS B 103 ? LYS L 103 . ? 1_555 ? 50 BC1 6 THR B 164 ? THR L 164 . ? 1_555 ? 51 BC1 6 ASP B 165 ? ASP L 165 . ? 1_555 ? 52 BC1 6 GLN B 166 ? GLN L 166 . ? 1_555 ? 53 BC1 6 TYR B 173 ? TYR L 173 . ? 1_555 ? 54 BC1 6 HOH O . ? HOH L 3017 . ? 1_555 ? # _database_PDB_matrix.entry_id 2OZ4 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2OZ4 _atom_sites.fract_transf_matrix[1][1] 0.005394 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.002263 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.014421 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.012299 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 1 ? -51.042 -32.583 -11.029 1.00 83.61 ? 186 VAL A N 1 ATOM 2 C CA . VAL A 1 1 ? -50.705 -31.160 -11.324 1.00 82.97 ? 186 VAL A CA 1 ATOM 3 C C . VAL A 1 1 ? -50.606 -30.351 -10.027 1.00 82.69 ? 186 VAL A C 1 ATOM 4 O O . VAL A 1 1 ? -51.237 -30.691 -9.023 1.00 82.73 ? 186 VAL A O 1 ATOM 5 C CB . VAL A 1 1 ? -51.758 -30.518 -12.271 1.00 83.34 ? 186 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 1 ? -53.083 -30.297 -11.544 1.00 82.96 ? 186 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 1 ? -51.235 -29.211 -12.858 1.00 83.73 ? 186 VAL A CG2 1 ATOM 8 N N . LEU A 1 2 ? -49.797 -29.295 -10.053 1.00 82.01 ? 187 LEU A N 1 ATOM 9 C CA . LEU A 1 2 ? -49.670 -28.379 -8.923 1.00 81.60 ? 187 LEU A CA 1 ATOM 10 C C . LEU A 1 2 ? -50.472 -27.112 -9.224 1.00 81.25 ? 187 LEU A C 1 ATOM 11 O O . LEU A 1 2 ? -50.287 -26.500 -10.276 1.00 81.42 ? 187 LEU A O 1 ATOM 12 C CB . LEU A 1 2 ? -48.199 -28.030 -8.689 1.00 81.35 ? 187 LEU A CB 1 ATOM 13 C CG . LEU A 1 2 ? -47.852 -27.364 -7.356 1.00 81.45 ? 187 LEU A CG 1 ATOM 14 C CD1 . LEU A 1 2 ? -48.057 -28.327 -6.203 1.00 81.57 ? 187 LEU A CD1 1 ATOM 15 C CD2 . LEU A 1 2 ? -46.421 -26.857 -7.373 1.00 81.38 ? 187 LEU A CD2 1 ATOM 16 N N . PRO A 1 3 ? -51.365 -26.711 -8.303 1.00 81.24 ? 188 PRO A N 1 ATOM 17 C CA . PRO A 1 3 ? -52.250 -25.578 -8.571 1.00 80.98 ? 188 PRO A CA 1 ATOM 18 C C . PRO A 1 3 ? -51.533 -24.228 -8.526 1.00 80.46 ? 188 PRO A C 1 ATOM 19 O O . PRO A 1 3 ? -50.434 -24.124 -7.979 1.00 80.21 ? 188 PRO A O 1 ATOM 20 C CB . PRO A 1 3 ? -53.284 -25.672 -7.444 1.00 81.34 ? 188 PRO A CB 1 ATOM 21 C CG . PRO A 1 3 ? -52.560 -26.319 -6.325 1.00 81.46 ? 188 PRO A CG 1 ATOM 22 C CD . PRO A 1 3 ? -51.588 -27.278 -6.959 1.00 81.70 ? 188 PRO A CD 1 ATOM 23 N N . ALA A 1 4 ? -52.169 -23.203 -9.090 1.00 80.32 ? 189 ALA A N 1 ATOM 24 C CA . ALA A 1 4 ? -51.618 -21.845 -9.090 1.00 80.18 ? 189 ALA A CA 1 ATOM 25 C C . ALA A 1 4 ? -51.710 -21.170 -7.716 1.00 79.92 ? 189 ALA A C 1 ATOM 26 O O . ALA A 1 4 ? -51.082 -20.136 -7.492 1.00 80.03 ? 189 ALA A O 1 ATOM 27 C CB . ALA A 1 4 ? -52.318 -20.994 -10.142 1.00 80.16 ? 189 ALA A CB 1 ATOM 28 N N . THR A 1 5 ? -52.496 -21.749 -6.808 1.00 80.00 ? 190 THR A N 1 ATOM 29 C CA . THR A 1 5 ? -52.616 -21.241 -5.440 1.00 79.74 ? 190 THR A CA 1 ATOM 30 C C . THR A 1 5 ? -51.355 -21.554 -4.624 1.00 78.94 ? 190 THR A C 1 ATOM 31 O O . THR A 1 5 ? -50.938 -22.713 -4.559 1.00 78.53 ? 190 THR A O 1 ATOM 32 C CB . THR A 1 5 ? -53.826 -21.870 -4.714 1.00 80.70 ? 190 THR A CB 1 ATOM 33 O OG1 . THR A 1 5 ? -54.988 -21.792 -5.552 1.00 81.40 ? 190 THR A OG1 1 ATOM 34 C CG2 . THR A 1 5 ? -54.099 -21.154 -3.394 1.00 80.45 ? 190 THR A CG2 1 ATOM 35 N N . PRO A 1 6 ? -50.740 -20.522 -4.006 1.00 78.74 ? 191 PRO A N 1 ATOM 36 C CA . PRO A 1 6 ? -49.611 -20.769 -3.100 1.00 78.41 ? 191 PRO A CA 1 ATOM 37 C C . PRO A 1 6 ? -50.035 -21.467 -1.802 1.00 77.74 ? 191 PRO A C 1 ATOM 38 O O . PRO A 1 6 ? -51.207 -21.395 -1.424 1.00 77.80 ? 191 PRO A O 1 ATOM 39 C CB . PRO A 1 6 ? -49.078 -19.359 -2.790 1.00 77.95 ? 191 PRO A CB 1 ATOM 40 C CG . PRO A 1 6 ? -49.737 -18.448 -3.761 1.00 78.28 ? 191 PRO A CG 1 ATOM 41 C CD . PRO A 1 6 ? -51.030 -19.084 -4.132 1.00 78.62 ? 191 PRO A CD 1 ATOM 42 N N . PRO A 1 7 ? -49.089 -22.142 -1.121 1.00 77.27 ? 192 PRO A N 1 ATOM 43 C CA . PRO A 1 7 ? -49.395 -22.764 0.171 1.00 77.80 ? 192 PRO A CA 1 ATOM 44 C C . PRO A 1 7 ? -49.721 -21.745 1.263 1.00 77.17 ? 192 PRO A C 1 ATOM 45 O O . PRO A 1 7 ? -49.185 -20.639 1.257 1.00 76.64 ? 192 PRO A O 1 ATOM 46 C CB . PRO A 1 7 ? -48.101 -23.517 0.524 1.00 77.86 ? 192 PRO A CB 1 ATOM 47 C CG . PRO A 1 7 ? -47.308 -23.573 -0.734 1.00 77.43 ? 192 PRO A CG 1 ATOM 48 C CD . PRO A 1 7 ? -47.693 -22.380 -1.526 1.00 77.25 ? 192 PRO A CD 1 ATOM 49 N N . GLN A 1 8 ? -50.597 -22.121 2.190 1.00 77.79 ? 193 GLN A N 1 ATOM 50 C CA . GLN A 1 8 ? -50.916 -21.265 3.328 1.00 77.78 ? 193 GLN A CA 1 ATOM 51 C C . GLN A 1 8 ? -49.923 -21.551 4.447 1.00 77.66 ? 193 GLN A C 1 ATOM 52 O O . GLN A 1 8 ? -49.702 -22.706 4.802 1.00 78.84 ? 193 GLN A O 1 ATOM 53 C CB . GLN A 1 8 ? -52.345 -21.512 3.813 1.00 77.93 ? 193 GLN A CB 1 ATOM 54 C CG . GLN A 1 8 ? -52.927 -20.346 4.611 1.00 78.47 ? 193 GLN A CG 1 ATOM 55 C CD . GLN A 1 8 ? -54.114 -20.744 5.474 1.00 78.73 ? 193 GLN A CD 1 ATOM 56 O OE1 . GLN A 1 8 ? -54.806 -21.723 5.191 1.00 79.64 ? 193 GLN A OE1 1 ATOM 57 N NE2 . GLN A 1 8 ? -54.353 -19.981 6.535 1.00 78.56 ? 193 GLN A NE2 1 ATOM 58 N N . LEU A 1 9 ? -49.319 -20.497 4.987 1.00 76.84 ? 194 LEU A N 1 ATOM 59 C CA . LEU A 1 9 ? -48.305 -20.630 6.030 1.00 76.96 ? 194 LEU A CA 1 ATOM 60 C C . LEU A 1 9 ? -48.771 -19.918 7.287 1.00 76.09 ? 194 LEU A C 1 ATOM 61 O O . LEU A 1 9 ? -49.105 -18.735 7.247 1.00 75.61 ? 194 LEU A O 1 ATOM 62 C CB . LEU A 1 9 ? -46.982 -20.028 5.559 1.00 77.33 ? 194 LEU A CB 1 ATOM 63 C CG . LEU A 1 9 ? -45.775 -20.209 6.481 1.00 76.89 ? 194 LEU A CG 1 ATOM 64 C CD1 . LEU A 1 9 ? -45.293 -21.649 6.452 1.00 76.78 ? 194 LEU A CD1 1 ATOM 65 C CD2 . LEU A 1 9 ? -44.662 -19.263 6.073 1.00 76.97 ? 194 LEU A CD2 1 ATOM 66 N N . VAL A 1 10 ? -48.793 -20.644 8.401 1.00 76.42 ? 195 VAL A N 1 ATOM 67 C CA . VAL A 1 10 ? -49.233 -20.089 9.675 1.00 77.28 ? 195 VAL A CA 1 ATOM 68 C C . VAL A 1 10 ? -48.084 -20.104 10.674 1.00 78.60 ? 195 VAL A C 1 ATOM 69 O O . VAL A 1 10 ? -47.533 -21.159 10.991 1.00 78.84 ? 195 VAL A O 1 ATOM 70 C CB . VAL A 1 10 ? -50.419 -20.874 10.250 1.00 75.69 ? 195 VAL A CB 1 ATOM 71 C CG1 . VAL A 1 10 ? -50.743 -20.396 11.657 1.00 75.18 ? 195 VAL A CG1 1 ATOM 72 C CG2 . VAL A 1 10 ? -51.629 -20.738 9.341 1.00 75.27 ? 195 VAL A CG2 1 ATOM 73 N N . SER A 1 11 ? -47.733 -18.918 11.163 1.00 78.89 ? 196 SER A N 1 ATOM 74 C CA . SER A 1 11 ? -46.633 -18.752 12.099 1.00 78.60 ? 196 SER A CA 1 ATOM 75 C C . SER A 1 11 ? -46.801 -17.429 12.840 1.00 78.37 ? 196 SER A C 1 ATOM 76 O O . SER A 1 11 ? -47.395 -16.492 12.303 1.00 78.33 ? 196 SER A O 1 ATOM 77 C CB . SER A 1 11 ? -45.302 -18.772 11.343 1.00 80.26 ? 196 SER A CB 1 ATOM 78 O OG . SER A 1 11 ? -44.286 -18.061 12.036 1.00 81.31 ? 196 SER A OG 1 ATOM 79 N N . PRO A 1 12 ? -46.285 -17.348 14.078 1.00 78.52 ? 197 PRO A N 1 ATOM 80 C CA . PRO A 1 12 ? -46.346 -16.080 14.801 1.00 78.36 ? 197 PRO A CA 1 ATOM 81 C C . PRO A 1 12 ? -45.441 -15.025 14.164 1.00 77.87 ? 197 PRO A C 1 ATOM 82 O O . PRO A 1 12 ? -44.415 -15.369 13.571 1.00 77.47 ? 197 PRO A O 1 ATOM 83 C CB . PRO A 1 12 ? -45.851 -16.453 16.202 1.00 78.64 ? 197 PRO A CB 1 ATOM 84 C CG . PRO A 1 12 ? -44.993 -17.650 15.992 1.00 78.55 ? 197 PRO A CG 1 ATOM 85 C CD . PRO A 1 12 ? -45.630 -18.405 14.872 1.00 78.57 ? 197 PRO A CD 1 ATOM 86 N N . ARG A 1 13 ? -45.828 -13.757 14.282 1.00 77.62 ? 198 ARG A N 1 ATOM 87 C CA . ARG A 1 13 ? -45.057 -12.653 13.704 1.00 77.79 ? 198 ARG A CA 1 ATOM 88 C C . ARG A 1 13 ? -43.739 -12.409 14.444 1.00 76.93 ? 198 ARG A C 1 ATOM 89 O O . ARG A 1 13 ? -42.797 -11.864 13.870 1.00 76.76 ? 198 ARG A O 1 ATOM 90 C CB . ARG A 1 13 ? -45.889 -11.367 13.685 1.00 78.68 ? 198 ARG A CB 1 ATOM 91 C CG . ARG A 1 13 ? -47.059 -11.404 12.707 1.00 79.51 ? 198 ARG A CG 1 ATOM 92 C CD . ARG A 1 13 ? -47.860 -10.106 12.733 1.00 79.58 ? 198 ARG A CD 1 ATOM 93 N NE . ARG A 1 13 ? -48.594 -9.935 13.990 1.00 80.19 ? 198 ARG A NE 1 ATOM 94 C CZ . ARG A 1 13 ? -49.750 -10.531 14.290 1.00 80.13 ? 198 ARG A CZ 1 ATOM 95 N NH1 . ARG A 1 13 ? -50.321 -10.299 15.467 1.00 79.95 ? 198 ARG A NH1 1 ATOM 96 N NH2 . ARG A 1 13 ? -50.337 -11.363 13.431 1.00 80.12 ? 198 ARG A NH2 1 ATOM 97 N N . VAL A 1 14 ? -43.683 -12.807 15.716 1.00 76.76 ? 199 VAL A N 1 ATOM 98 C CA . VAL A 1 14 ? -42.470 -12.680 16.527 1.00 75.97 ? 199 VAL A CA 1 ATOM 99 C C . VAL A 1 14 ? -42.210 -13.956 17.330 1.00 75.37 ? 199 VAL A C 1 ATOM 100 O O . VAL A 1 14 ? -43.118 -14.758 17.552 1.00 75.01 ? 199 VAL A O 1 ATOM 101 C CB . VAL A 1 14 ? -42.564 -11.487 17.501 1.00 75.42 ? 199 VAL A CB 1 ATOM 102 C CG1 . VAL A 1 14 ? -42.744 -10.183 16.735 1.00 75.07 ? 199 VAL A CG1 1 ATOM 103 C CG2 . VAL A 1 14 ? -43.702 -11.693 18.496 1.00 75.35 ? 199 VAL A CG2 1 ATOM 104 N N . LEU A 1 15 ? -40.965 -14.132 17.765 1.00 75.21 ? 200 LEU A N 1 ATOM 105 C CA . LEU A 1 15 ? -40.567 -15.317 18.523 1.00 74.99 ? 200 LEU A CA 1 ATOM 106 C C . LEU A 1 15 ? -39.391 -14.980 19.443 1.00 74.35 ? 200 LEU A C 1 ATOM 107 O O . LEU A 1 15 ? -38.383 -14.441 18.995 1.00 73.83 ? 200 LEU A O 1 ATOM 108 C CB . LEU A 1 15 ? -40.186 -16.446 17.560 1.00 75.16 ? 200 LEU A CB 1 ATOM 109 C CG . LEU A 1 15 ? -40.153 -17.867 18.126 1.00 75.33 ? 200 LEU A CG 1 ATOM 110 C CD1 . LEU A 1 15 ? -41.553 -18.333 18.501 1.00 75.78 ? 200 LEU A CD1 1 ATOM 111 C CD2 . LEU A 1 15 ? -39.525 -18.821 17.121 1.00 74.92 ? 200 LEU A CD2 1 ATOM 112 N N . GLU A 1 16 ? -39.528 -15.292 20.730 1.00 74.75 ? 201 GLU A N 1 ATOM 113 C CA . GLU A 1 16 ? -38.499 -14.951 21.714 1.00 74.90 ? 201 GLU A CA 1 ATOM 114 C C . GLU A 1 16 ? -37.308 -15.904 21.612 1.00 74.95 ? 201 GLU A C 1 ATOM 115 O O . GLU A 1 16 ? -37.465 -17.065 21.240 1.00 75.26 ? 201 GLU A O 1 ATOM 116 C CB . GLU A 1 16 ? -39.078 -14.979 23.133 1.00 74.76 ? 201 GLU A CB 1 ATOM 117 C CG . GLU A 1 16 ? -38.208 -14.278 24.181 1.00 74.91 ? 201 GLU A CG 1 ATOM 118 C CD . GLU A 1 16 ? -38.768 -14.384 25.595 1.00 75.22 ? 201 GLU A CD 1 ATOM 119 O OE1 . GLU A 1 16 ? -39.994 -14.570 25.751 1.00 75.10 ? 201 GLU A OE1 1 ATOM 120 O OE2 . GLU A 1 16 ? -37.975 -14.277 26.555 1.00 75.47 ? 201 GLU A OE2 1 ATOM 121 N N . VAL A 1 17 ? -36.121 -15.402 21.943 1.00 74.69 ? 202 VAL A N 1 ATOM 122 C CA . VAL A 1 17 ? -34.908 -16.220 21.959 1.00 74.68 ? 202 VAL A CA 1 ATOM 123 C C . VAL A 1 17 ? -35.032 -17.327 23.011 1.00 75.01 ? 202 VAL A C 1 ATOM 124 O O . VAL A 1 17 ? -35.669 -17.136 24.049 1.00 75.39 ? 202 VAL A O 1 ATOM 125 C CB . VAL A 1 17 ? -33.652 -15.360 22.254 1.00 74.18 ? 202 VAL A CB 1 ATOM 126 C CG1 . VAL A 1 17 ? -32.411 -16.232 22.389 1.00 73.68 ? 202 VAL A CG1 1 ATOM 127 C CG2 . VAL A 1 17 ? -33.452 -14.321 21.163 1.00 74.43 ? 202 VAL A CG2 1 ATOM 128 N N . ASP A 1 18 ? -34.431 -18.482 22.723 1.00 75.08 ? 203 ASP A N 1 ATOM 129 C CA . ASP A 1 18 ? -34.472 -19.653 23.614 1.00 75.01 ? 203 ASP A CA 1 ATOM 130 C C . ASP A 1 18 ? -35.902 -20.108 23.924 1.00 74.34 ? 203 ASP A C 1 ATOM 131 O O . ASP A 1 18 ? -36.201 -20.525 25.041 1.00 73.74 ? 203 ASP A O 1 ATOM 132 C CB . ASP A 1 18 ? -33.702 -19.378 24.917 1.00 75.00 ? 203 ASP A CB 1 ATOM 133 C CG . ASP A 1 18 ? -32.244 -19.022 24.676 1.00 75.03 ? 203 ASP A CG 1 ATOM 134 O OD1 . ASP A 1 18 ? -31.632 -19.584 23.741 1.00 74.94 ? 203 ASP A OD1 1 ATOM 135 O OD2 . ASP A 1 18 ? -31.706 -18.187 25.433 1.00 75.14 ? 203 ASP A OD2 1 ATOM 136 N N . THR A 1 19 ? -36.780 -20.015 22.929 1.00 75.11 ? 204 THR A N 1 ATOM 137 C CA . THR A 1 19 ? -38.148 -20.521 23.046 1.00 75.81 ? 204 THR A CA 1 ATOM 138 C C . THR A 1 19 ? -38.535 -21.277 21.779 1.00 76.13 ? 204 THR A C 1 ATOM 139 O O . THR A 1 19 ? -37.972 -21.047 20.707 1.00 75.97 ? 204 THR A O 1 ATOM 140 C CB . THR A 1 19 ? -39.174 -19.388 23.296 1.00 75.61 ? 204 THR A CB 1 ATOM 141 O OG1 . THR A 1 19 ? -39.309 -18.580 22.119 1.00 75.51 ? 204 THR A OG1 1 ATOM 142 C CG2 . THR A 1 19 ? -38.747 -18.517 24.472 1.00 75.22 ? 204 THR A CG2 1 ATOM 143 N N . GLN A 1 20 ? -39.502 -22.176 21.915 1.00 76.66 ? 205 GLN A N 1 ATOM 144 C CA . GLN A 1 20 ? -39.928 -23.029 20.816 1.00 76.78 ? 205 GLN A CA 1 ATOM 145 C C . GLN A 1 20 ? -41.172 -22.445 20.150 1.00 76.47 ? 205 GLN A C 1 ATOM 146 O O . GLN A 1 20 ? -42.144 -22.103 20.824 1.00 76.30 ? 205 GLN A O 1 ATOM 147 C CB . GLN A 1 20 ? -40.215 -24.440 21.339 1.00 77.19 ? 205 GLN A CB 1 ATOM 148 C CG . GLN A 1 20 ? -40.166 -25.531 20.276 1.00 77.25 ? 205 GLN A CG 1 ATOM 149 C CD . GLN A 1 20 ? -40.283 -26.930 20.864 1.00 77.59 ? 205 GLN A CD 1 ATOM 150 O OE1 . GLN A 1 20 ? -40.978 -27.789 20.318 1.00 78.27 ? 205 GLN A OE1 1 ATOM 151 N NE2 . GLN A 1 20 ? -39.605 -27.163 21.982 1.00 77.56 ? 205 GLN A NE2 1 ATOM 152 N N . GLY A 1 21 ? -41.125 -22.316 18.827 1.00 76.74 ? 206 GLY A N 1 ATOM 153 C CA . GLY A 1 21 ? -42.273 -21.856 18.047 1.00 76.85 ? 206 GLY A CA 1 ATOM 154 C C . GLY A 1 21 ? -43.013 -23.019 17.410 1.00 76.80 ? 206 GLY A C 1 ATOM 155 O O . GLY A 1 21 ? -42.595 -24.172 17.533 1.00 77.02 ? 206 GLY A O 1 ATOM 156 N N . THR A 1 22 ? -44.122 -22.716 16.738 1.00 76.27 ? 207 THR A N 1 ATOM 157 C CA . THR A 1 22 ? -44.888 -23.726 16.008 1.00 76.10 ? 207 THR A CA 1 ATOM 158 C C . THR A 1 22 ? -45.335 -23.176 14.659 1.00 75.42 ? 207 THR A C 1 ATOM 159 O O . THR A 1 22 ? -46.041 -22.168 14.591 1.00 74.86 ? 207 THR A O 1 ATOM 160 C CB . THR A 1 22 ? -46.128 -24.183 16.795 1.00 75.88 ? 207 THR A CB 1 ATOM 161 O OG1 . THR A 1 22 ? -45.764 -24.462 18.153 1.00 76.06 ? 207 THR A OG1 1 ATOM 162 C CG2 . THR A 1 22 ? -46.728 -25.433 16.162 1.00 75.77 ? 207 THR A CG2 1 ATOM 163 N N . VAL A 1 23 ? -44.912 -23.846 13.591 1.00 75.54 ? 208 VAL A N 1 ATOM 164 C CA . VAL A 1 23 ? -45.238 -23.440 12.231 1.00 75.97 ? 208 VAL A CA 1 ATOM 165 C C . VAL A 1 23 ? -46.003 -24.556 11.536 1.00 75.51 ? 208 VAL A C 1 ATOM 166 O O . VAL A 1 23 ? -45.615 -25.719 11.625 1.00 75.53 ? 208 VAL A O 1 ATOM 167 C CB . VAL A 1 23 ? -43.962 -23.142 11.427 1.00 76.08 ? 208 VAL A CB 1 ATOM 168 C CG1 . VAL A 1 23 ? -44.299 -22.849 9.971 1.00 76.25 ? 208 VAL A CG1 1 ATOM 169 C CG2 . VAL A 1 23 ? -43.207 -21.983 12.051 1.00 76.18 ? 208 VAL A CG2 1 ATOM 170 N N . VAL A 1 24 ? -47.090 -24.201 10.853 1.00 76.26 ? 209 VAL A N 1 ATOM 171 C CA . VAL A 1 24 ? -47.833 -25.161 10.035 1.00 76.97 ? 209 VAL A CA 1 ATOM 172 C C . VAL A 1 24 ? -48.034 -24.625 8.621 1.00 77.75 ? 209 VAL A C 1 ATOM 173 O O . VAL A 1 24 ? -48.417 -23.469 8.433 1.00 77.47 ? 209 VAL A O 1 ATOM 174 C CB . VAL A 1 24 ? -49.202 -25.540 10.660 1.00 76.71 ? 209 VAL A CB 1 ATOM 175 C CG1 . VAL A 1 24 ? -50.074 -24.318 10.854 1.00 76.93 ? 209 VAL A CG1 1 ATOM 176 C CG2 . VAL A 1 24 ? -49.913 -26.570 9.792 1.00 76.67 ? 209 VAL A CG2 1 ATOM 177 N N . CYS A 1 25 ? -47.757 -25.476 7.635 1.00 79.56 ? 210 CYS A N 1 ATOM 178 C CA . CYS A 1 25 ? -47.897 -25.126 6.225 1.00 78.28 ? 210 CYS A CA 1 ATOM 179 C C . CYS A 1 25 ? -48.778 -26.150 5.517 1.00 78.20 ? 210 CYS A C 1 ATOM 180 O O . CYS A 1 25 ? -48.604 -27.354 5.705 1.00 79.27 ? 210 CYS A O 1 ATOM 181 C CB . CYS A 1 25 ? -46.529 -25.077 5.552 1.00 80.33 ? 210 CYS A CB 1 ATOM 182 S SG . CYS A 1 25 ? -46.612 -24.537 3.839 1.00 82.85 ? 210 CYS A SG 1 ATOM 183 N N . SER A 1 26 ? -49.707 -25.672 4.690 1.00 76.98 ? 211 SER A N 1 ATOM 184 C CA . SER A 1 26 ? -50.701 -26.546 4.067 1.00 76.13 ? 211 SER A CA 1 ATOM 185 C C . SER A 1 26 ? -51.047 -26.128 2.641 1.00 74.80 ? 211 SER A C 1 ATOM 186 O O . SER A 1 26 ? -50.921 -24.958 2.277 1.00 74.30 ? 211 SER A O 1 ATOM 187 C CB . SER A 1 26 ? -51.975 -26.556 4.910 1.00 76.70 ? 211 SER A CB 1 ATOM 188 O OG . SER A 1 26 ? -52.603 -25.284 4.897 1.00 76.91 ? 211 SER A OG 1 ATOM 189 N N . LEU A 1 27 ? -51.490 -27.100 1.846 1.00 74.11 ? 212 LEU A N 1 ATOM 190 C CA . LEU A 1 27 ? -51.940 -26.855 0.477 1.00 74.32 ? 212 LEU A CA 1 ATOM 191 C C . LEU A 1 27 ? -52.895 -27.960 0.027 1.00 73.28 ? 212 LEU A C 1 ATOM 192 O O . LEU A 1 27 ? -52.671 -29.135 0.319 1.00 71.82 ? 212 LEU A O 1 ATOM 193 C CB . LEU A 1 27 ? -50.742 -26.781 -0.477 1.00 74.48 ? 212 LEU A CB 1 ATOM 194 C CG . LEU A 1 27 ? -51.025 -26.403 -1.937 1.00 73.64 ? 212 LEU A CG 1 ATOM 195 C CD1 . LEU A 1 27 ? -51.759 -25.078 -2.031 1.00 73.17 ? 212 LEU A CD1 1 ATOM 196 C CD2 . LEU A 1 27 ? -49.733 -26.345 -2.724 1.00 73.53 ? 212 LEU A CD2 1 ATOM 197 N N . ASP A 1 28 ? -53.955 -27.566 -0.678 1.00 74.31 ? 213 ASP A N 1 ATOM 198 C CA . ASP A 1 28 ? -54.954 -28.501 -1.204 1.00 74.79 ? 213 ASP A CA 1 ATOM 199 C C . ASP A 1 28 ? -55.030 -28.398 -2.725 1.00 74.23 ? 213 ASP A C 1 ATOM 200 O O . ASP A 1 28 ? -54.797 -27.332 -3.295 1.00 73.54 ? 213 ASP A O 1 ATOM 201 C CB . ASP A 1 28 ? -56.331 -28.203 -0.597 1.00 74.47 ? 213 ASP A CB 1 ATOM 202 C CG . ASP A 1 28 ? -57.414 -29.160 -1.088 1.00 74.29 ? 213 ASP A CG 1 ATOM 203 O OD1 . ASP A 1 28 ? -57.207 -30.388 -1.016 1.00 74.06 ? 213 ASP A OD1 1 ATOM 204 O OD2 . ASP A 1 28 ? -58.476 -28.685 -1.544 1.00 74.27 ? 213 ASP A OD2 1 ATOM 205 N N . GLY A 1 29 ? -55.356 -29.514 -3.373 1.00 74.82 ? 214 GLY A N 1 ATOM 206 C CA . GLY A 1 29 ? -55.582 -29.536 -4.817 1.00 76.28 ? 214 GLY A CA 1 ATOM 207 C C . GLY A 1 29 ? -54.371 -29.945 -5.635 1.00 77.41 ? 214 GLY A C 1 ATOM 208 O O . GLY A 1 29 ? -54.247 -29.551 -6.795 1.00 78.36 ? 214 GLY A O 1 ATOM 209 N N . LEU A 1 30 ? -53.482 -30.741 -5.044 1.00 77.57 ? 215 LEU A N 1 ATOM 210 C CA . LEU A 1 30 ? -52.293 -31.222 -5.746 1.00 78.35 ? 215 LEU A CA 1 ATOM 211 C C . LEU A 1 30 ? -52.262 -32.744 -5.781 1.00 78.49 ? 215 LEU A C 1 ATOM 212 O O . LEU A 1 30 ? -52.720 -33.403 -4.849 1.00 78.59 ? 215 LEU A O 1 ATOM 213 C CB . LEU A 1 30 ? -51.015 -30.667 -5.101 1.00 78.87 ? 215 LEU A CB 1 ATOM 214 C CG . LEU A 1 30 ? -50.672 -31.071 -3.662 1.00 78.99 ? 215 LEU A CG 1 ATOM 215 C CD1 . LEU A 1 30 ? -50.015 -32.439 -3.609 1.00 78.95 ? 215 LEU A CD1 1 ATOM 216 C CD2 . LEU A 1 30 ? -49.757 -30.031 -3.034 1.00 78.91 ? 215 LEU A CD2 1 ATOM 217 N N . PHE A 1 31 ? -51.725 -33.294 -6.867 1.00 79.14 ? 216 PHE A N 1 ATOM 218 C CA . PHE A 1 31 ? -51.605 -34.744 -7.020 1.00 79.95 ? 216 PHE A CA 1 ATOM 219 C C . PHE A 1 31 ? -50.585 -35.098 -8.109 1.00 78.80 ? 216 PHE A C 1 ATOM 220 O O . PHE A 1 31 ? -50.417 -34.340 -9.063 1.00 77.91 ? 216 PHE A O 1 ATOM 221 C CB . PHE A 1 31 ? -52.967 -35.365 -7.351 1.00 82.58 ? 216 PHE A CB 1 ATOM 222 C CG . PHE A 1 31 ? -53.682 -34.689 -8.487 1.00 83.14 ? 216 PHE A CG 1 ATOM 223 C CD1 . PHE A 1 31 ? -54.547 -33.626 -8.248 1.00 83.25 ? 216 PHE A CD1 1 ATOM 224 C CD2 . PHE A 1 31 ? -53.489 -35.112 -9.797 1.00 83.16 ? 216 PHE A CD2 1 ATOM 225 C CE1 . PHE A 1 31 ? -55.208 -32.995 -9.296 1.00 83.07 ? 216 PHE A CE1 1 ATOM 226 C CE2 . PHE A 1 31 ? -54.145 -34.484 -10.851 1.00 83.03 ? 216 PHE A CE2 1 ATOM 227 C CZ . PHE A 1 31 ? -55.006 -33.424 -10.599 1.00 82.99 ? 216 PHE A CZ 1 ATOM 228 N N . PRO A 1 32 ? -49.889 -36.243 -7.961 1.00 78.93 ? 217 PRO A N 1 ATOM 229 C CA . PRO A 1 32 ? -49.936 -37.153 -6.811 1.00 79.28 ? 217 PRO A CA 1 ATOM 230 C C . PRO A 1 32 ? -49.197 -36.582 -5.599 1.00 79.12 ? 217 PRO A C 1 ATOM 231 O O . PRO A 1 32 ? -48.050 -36.152 -5.721 1.00 79.13 ? 217 PRO A O 1 ATOM 232 C CB . PRO A 1 32 ? -49.232 -38.423 -7.325 1.00 79.05 ? 217 PRO A CB 1 ATOM 233 C CG . PRO A 1 32 ? -49.001 -38.205 -8.794 1.00 78.95 ? 217 PRO A CG 1 ATOM 234 C CD . PRO A 1 32 ? -48.969 -36.737 -8.997 1.00 78.87 ? 217 PRO A CD 1 ATOM 235 N N . VAL A 1 33 ? -49.853 -36.590 -4.441 1.00 79.35 ? 218 VAL A N 1 ATOM 236 C CA . VAL A 1 33 ? -49.301 -35.964 -3.237 1.00 79.82 ? 218 VAL A CA 1 ATOM 237 C C . VAL A 1 33 ? -48.049 -36.688 -2.737 1.00 79.80 ? 218 VAL A C 1 ATOM 238 O O . VAL A 1 33 ? -47.147 -36.061 -2.177 1.00 79.83 ? 218 VAL A O 1 ATOM 239 C CB . VAL A 1 33 ? -50.338 -35.901 -2.088 1.00 80.69 ? 218 VAL A CB 1 ATOM 240 C CG1 . VAL A 1 33 ? -49.816 -35.040 -0.950 1.00 80.78 ? 218 VAL A CG1 1 ATOM 241 C CG2 . VAL A 1 33 ? -51.671 -35.356 -2.589 1.00 81.50 ? 218 VAL A CG2 1 ATOM 242 N N . SER A 1 34 ? -47.994 -38.001 -2.949 1.00 80.02 ? 219 SER A N 1 ATOM 243 C CA . SER A 1 34 ? -46.839 -38.808 -2.544 1.00 80.21 ? 219 SER A CA 1 ATOM 244 C C . SER A 1 34 ? -45.545 -38.372 -3.243 1.00 80.52 ? 219 SER A C 1 ATOM 245 O O . SER A 1 34 ? -44.459 -38.487 -2.670 1.00 80.45 ? 219 SER A O 1 ATOM 246 C CB . SER A 1 34 ? -47.104 -40.291 -2.822 1.00 80.25 ? 219 SER A CB 1 ATOM 247 O OG . SER A 1 34 ? -47.443 -40.502 -4.183 1.00 80.04 ? 219 SER A OG 1 ATOM 248 N N . GLU A 1 35 ? -45.667 -37.875 -4.474 1.00 80.39 ? 220 GLU A N 1 ATOM 249 C CA . GLU A 1 35 ? -44.513 -37.391 -5.239 1.00 80.06 ? 220 GLU A CA 1 ATOM 250 C C . GLU A 1 35 ? -44.108 -35.960 -4.862 1.00 79.47 ? 220 GLU A C 1 ATOM 251 O O . GLU A 1 35 ? -43.029 -35.500 -5.239 1.00 79.22 ? 220 GLU A O 1 ATOM 252 C CB . GLU A 1 35 ? -44.800 -37.467 -6.743 1.00 80.43 ? 220 GLU A CB 1 ATOM 253 C CG . GLU A 1 35 ? -45.030 -38.884 -7.261 1.00 81.03 ? 220 GLU A CG 1 ATOM 254 C CD . GLU A 1 35 ? -45.002 -38.974 -8.782 1.00 81.49 ? 220 GLU A CD 1 ATOM 255 O OE1 . GLU A 1 35 ? -45.541 -38.066 -9.452 1.00 82.26 ? 220 GLU A OE1 1 ATOM 256 O OE2 . GLU A 1 35 ? -44.443 -39.960 -9.309 1.00 81.82 ? 220 GLU A OE2 1 ATOM 257 N N . ALA A 1 36 ? -44.970 -35.263 -4.123 1.00 79.13 ? 221 ALA A N 1 ATOM 258 C CA . ALA A 1 36 ? -44.714 -33.875 -3.729 1.00 78.63 ? 221 ALA A CA 1 ATOM 259 C C . ALA A 1 36 ? -43.657 -33.787 -2.631 1.00 78.31 ? 221 ALA A C 1 ATOM 260 O O . ALA A 1 36 ? -43.691 -34.550 -1.666 1.00 78.73 ? 221 ALA A O 1 ATOM 261 C CB . ALA A 1 36 ? -46.002 -33.215 -3.263 1.00 77.80 ? 221 ALA A CB 1 ATOM 262 N N . GLN A 1 37 ? -42.723 -32.852 -2.788 1.00 77.95 ? 222 GLN A N 1 ATOM 263 C CA . GLN A 1 37 ? -41.719 -32.572 -1.766 1.00 78.17 ? 222 GLN A CA 1 ATOM 264 C C . GLN A 1 37 ? -42.058 -31.248 -1.093 1.00 78.15 ? 222 GLN A C 1 ATOM 265 O O . GLN A 1 37 ? -42.255 -30.239 -1.771 1.00 77.91 ? 222 GLN A O 1 ATOM 266 C CB . GLN A 1 37 ? -40.317 -32.478 -2.379 1.00 78.08 ? 222 GLN A CB 1 ATOM 267 C CG . GLN A 1 37 ? -39.952 -33.597 -3.347 1.00 78.14 ? 222 GLN A CG 1 ATOM 268 C CD . GLN A 1 37 ? -38.645 -33.328 -4.077 1.00 78.39 ? 222 GLN A CD 1 ATOM 269 O OE1 . GLN A 1 37 ? -38.582 -33.394 -5.305 1.00 78.48 ? 222 GLN A OE1 1 ATOM 270 N NE2 . GLN A 1 37 ? -37.598 -33.009 -3.322 1.00 78.52 ? 222 GLN A NE2 1 ATOM 271 N N . VAL A 1 38 ? -42.127 -31.258 0.237 1.00 78.14 ? 223 VAL A N 1 ATOM 272 C CA . VAL A 1 38 ? -42.358 -30.043 1.009 1.00 78.22 ? 223 VAL A CA 1 ATOM 273 C C . VAL A 1 38 ? -41.072 -29.651 1.720 1.00 78.78 ? 223 VAL A C 1 ATOM 274 O O . VAL A 1 38 ? -40.521 -30.437 2.492 1.00 79.51 ? 223 VAL A O 1 ATOM 275 C CB . VAL A 1 38 ? -43.474 -30.237 2.051 1.00 77.63 ? 223 VAL A CB 1 ATOM 276 C CG1 . VAL A 1 38 ? -43.747 -28.931 2.791 1.00 77.47 ? 223 VAL A CG1 1 ATOM 277 C CG2 . VAL A 1 38 ? -44.740 -30.749 1.383 1.00 77.13 ? 223 VAL A CG2 1 ATOM 278 N N . HIS A 1 39 ? -40.593 -28.440 1.446 1.00 79.22 ? 224 HIS A N 1 ATOM 279 C CA . HIS A 1 39 ? -39.386 -27.912 2.076 1.00 79.41 ? 224 HIS A CA 1 ATOM 280 C C . HIS A 1 39 ? -39.747 -26.744 2.988 1.00 79.56 ? 224 HIS A C 1 ATOM 281 O O . HIS A 1 39 ? -40.134 -25.673 2.518 1.00 79.75 ? 224 HIS A O 1 ATOM 282 C CB . HIS A 1 39 ? -38.383 -27.460 1.015 1.00 80.51 ? 224 HIS A CB 1 ATOM 283 C CG . HIS A 1 39 ? -37.856 -28.577 0.168 1.00 81.51 ? 224 HIS A CG 1 ATOM 284 N ND1 . HIS A 1 39 ? -36.727 -29.294 0.501 1.00 81.97 ? 224 HIS A ND1 1 ATOM 285 C CD2 . HIS A 1 39 ? -38.301 -29.098 -1.000 1.00 81.79 ? 224 HIS A CD2 1 ATOM 286 C CE1 . HIS A 1 39 ? -36.499 -30.209 -0.425 1.00 81.66 ? 224 HIS A CE1 1 ATOM 287 N NE2 . HIS A 1 39 ? -37.440 -30.112 -1.347 1.00 81.97 ? 224 HIS A NE2 1 ATOM 288 N N . LEU A 1 40 ? -39.622 -26.965 4.294 1.00 79.45 ? 225 LEU A N 1 ATOM 289 C CA . LEU A 1 40 ? -39.960 -25.962 5.296 1.00 79.54 ? 225 LEU A CA 1 ATOM 290 C C . LEU A 1 40 ? -38.677 -25.504 5.985 1.00 79.40 ? 225 LEU A C 1 ATOM 291 O O . LEU A 1 40 ? -37.865 -26.334 6.397 1.00 79.05 ? 225 LEU A O 1 ATOM 292 C CB . LEU A 1 40 ? -40.935 -26.564 6.312 1.00 79.37 ? 225 LEU A CB 1 ATOM 293 C CG . LEU A 1 40 ? -41.682 -25.617 7.252 1.00 79.65 ? 225 LEU A CG 1 ATOM 294 C CD1 . LEU A 1 40 ? -42.463 -24.562 6.481 1.00 79.61 ? 225 LEU A CD1 1 ATOM 295 C CD2 . LEU A 1 40 ? -42.610 -26.415 8.158 1.00 79.68 ? 225 LEU A CD2 1 ATOM 296 N N . ALA A 1 41 ? -38.491 -24.190 6.098 1.00 79.52 ? 226 ALA A N 1 ATOM 297 C CA . ALA A 1 41 ? -37.259 -23.641 6.666 1.00 80.30 ? 226 ALA A CA 1 ATOM 298 C C . ALA A 1 41 ? -37.434 -22.218 7.197 1.00 80.90 ? 226 ALA A C 1 ATOM 299 O O . ALA A 1 41 ? -38.183 -21.423 6.631 1.00 81.00 ? 226 ALA A O 1 ATOM 300 C CB . ALA A 1 41 ? -36.149 -23.677 5.630 1.00 79.97 ? 226 ALA A CB 1 ATOM 301 N N . LEU A 1 42 ? -36.735 -21.916 8.291 1.00 81.67 ? 227 LEU A N 1 ATOM 302 C CA . LEU A 1 42 ? -36.699 -20.572 8.867 1.00 82.17 ? 227 LEU A CA 1 ATOM 303 C C . LEU A 1 42 ? -35.302 -19.995 8.679 1.00 83.45 ? 227 LEU A C 1 ATOM 304 O O . LEU A 1 42 ? -34.386 -20.303 9.444 1.00 84.16 ? 227 LEU A O 1 ATOM 305 C CB . LEU A 1 42 ? -37.058 -20.617 10.356 1.00 81.96 ? 227 LEU A CB 1 ATOM 306 C CG . LEU A 1 42 ? -36.958 -19.305 11.145 1.00 81.88 ? 227 LEU A CG 1 ATOM 307 C CD1 . LEU A 1 42 ? -37.838 -18.226 10.534 1.00 81.92 ? 227 LEU A CD1 1 ATOM 308 C CD2 . LEU A 1 42 ? -37.331 -19.534 12.601 1.00 82.03 ? 227 LEU A CD2 1 ATOM 309 N N . GLY A 1 43 ? -35.143 -19.161 7.655 1.00 83.97 ? 228 GLY A N 1 ATOM 310 C CA . GLY A 1 43 ? -33.837 -18.625 7.293 1.00 84.08 ? 228 GLY A CA 1 ATOM 311 C C . GLY A 1 43 ? -32.956 -19.708 6.696 1.00 85.46 ? 228 GLY A C 1 ATOM 312 O O . GLY A 1 43 ? -33.235 -20.214 5.605 1.00 86.03 ? 228 GLY A O 1 ATOM 313 N N . ASP A 1 44 ? -31.895 -20.067 7.417 1.00 85.87 ? 229 ASP A N 1 ATOM 314 C CA . ASP A 1 44 ? -30.969 -21.117 6.981 1.00 85.22 ? 229 ASP A CA 1 ATOM 315 C C . ASP A 1 44 ? -31.348 -22.483 7.570 1.00 85.30 ? 229 ASP A C 1 ATOM 316 O O . ASP A 1 44 ? -31.037 -23.525 6.988 1.00 85.41 ? 229 ASP A O 1 ATOM 317 C CB . ASP A 1 44 ? -29.534 -20.751 7.384 1.00 85.62 ? 229 ASP A CB 1 ATOM 318 C CG . ASP A 1 44 ? -28.483 -21.581 6.656 1.00 86.07 ? 229 ASP A CG 1 ATOM 319 O OD1 . ASP A 1 44 ? -28.800 -22.180 5.604 1.00 86.38 ? 229 ASP A OD1 1 ATOM 320 O OD2 . ASP A 1 44 ? -27.331 -21.627 7.137 1.00 86.21 ? 229 ASP A OD2 1 ATOM 321 N N . GLN A 1 45 ? -32.024 -22.464 8.718 1.00 84.55 ? 230 GLN A N 1 ATOM 322 C CA . GLN A 1 45 ? -32.390 -23.685 9.434 1.00 84.12 ? 230 GLN A CA 1 ATOM 323 C C . GLN A 1 45 ? -33.503 -24.454 8.710 1.00 83.69 ? 230 GLN A C 1 ATOM 324 O O . GLN A 1 45 ? -34.642 -23.991 8.640 1.00 83.50 ? 230 GLN A O 1 ATOM 325 C CB . GLN A 1 45 ? -32.831 -23.332 10.861 1.00 84.23 ? 230 GLN A CB 1 ATOM 326 C CG . GLN A 1 45 ? -33.015 -24.524 11.794 1.00 84.38 ? 230 GLN A CG 1 ATOM 327 C CD . GLN A 1 45 ? -33.509 -24.113 13.174 1.00 84.37 ? 230 GLN A CD 1 ATOM 328 O OE1 . GLN A 1 45 ? -33.135 -23.059 13.694 1.00 84.43 ? 230 GLN A OE1 1 ATOM 329 N NE2 . GLN A 1 45 ? -34.354 -24.947 13.773 1.00 84.29 ? 230 GLN A NE2 1 ATOM 330 N N . ARG A 1 46 ? -33.160 -25.624 8.171 1.00 83.33 ? 231 ARG A N 1 ATOM 331 C CA . ARG A 1 46 ? -34.143 -26.510 7.540 1.00 82.79 ? 231 ARG A CA 1 ATOM 332 C C . ARG A 1 46 ? -34.972 -27.212 8.613 1.00 81.83 ? 231 ARG A C 1 ATOM 333 O O . ARG A 1 46 ? -34.430 -27.963 9.426 1.00 81.67 ? 231 ARG A O 1 ATOM 334 C CB . ARG A 1 46 ? -33.446 -27.563 6.672 1.00 83.51 ? 231 ARG A CB 1 ATOM 335 C CG . ARG A 1 46 ? -32.721 -27.009 5.450 1.00 83.88 ? 231 ARG A CG 1 ATOM 336 C CD . ARG A 1 46 ? -31.751 -28.042 4.880 1.00 83.76 ? 231 ARG A CD 1 ATOM 337 N NE . ARG A 1 46 ? -31.236 -27.673 3.559 1.00 83.93 ? 231 ARG A NE 1 ATOM 338 C CZ . ARG A 1 46 ? -31.860 -27.897 2.400 1.00 84.21 ? 231 ARG A CZ 1 ATOM 339 N NH1 . ARG A 1 46 ? -33.054 -28.487 2.365 1.00 84.29 ? 231 ARG A NH1 1 ATOM 340 N NH2 . ARG A 1 46 ? -31.286 -27.521 1.260 1.00 84.06 ? 231 ARG A NH2 1 ATOM 341 N N . LEU A 1 47 ? -36.281 -26.968 8.608 1.00 81.09 ? 232 LEU A N 1 ATOM 342 C CA . LEU A 1 47 ? -37.182 -27.552 9.603 1.00 80.31 ? 232 LEU A CA 1 ATOM 343 C C . LEU A 1 47 ? -37.549 -28.988 9.239 1.00 79.93 ? 232 LEU A C 1 ATOM 344 O O . LEU A 1 47 ? -37.409 -29.400 8.087 1.00 79.91 ? 232 LEU A O 1 ATOM 345 C CB . LEU A 1 47 ? -38.452 -26.708 9.735 1.00 78.72 ? 232 LEU A CB 1 ATOM 346 C CG . LEU A 1 47 ? -38.240 -25.264 10.197 1.00 77.61 ? 232 LEU A CG 1 ATOM 347 C CD1 . LEU A 1 47 ? -39.534 -24.475 10.115 1.00 76.60 ? 232 LEU A CD1 1 ATOM 348 C CD2 . LEU A 1 47 ? -37.677 -25.230 11.609 1.00 77.85 ? 232 LEU A CD2 1 ATOM 349 N N . ASN A 1 48 ? -38.009 -29.744 10.234 1.00 79.80 ? 233 ASN A N 1 ATOM 350 C CA . ASN A 1 48 ? -38.443 -31.126 10.033 1.00 79.72 ? 233 ASN A CA 1 ATOM 351 C C . ASN A 1 48 ? -39.921 -31.279 10.397 1.00 79.29 ? 233 ASN A C 1 ATOM 352 O O . ASN A 1 48 ? -40.253 -31.600 11.541 1.00 78.90 ? 233 ASN A O 1 ATOM 353 C CB . ASN A 1 48 ? -37.581 -32.086 10.863 1.00 80.08 ? 233 ASN A CB 1 ATOM 354 C CG . ASN A 1 48 ? -37.924 -33.554 10.617 1.00 80.17 ? 233 ASN A CG 1 ATOM 355 O OD1 . ASN A 1 48 ? -38.478 -33.914 9.575 1.00 80.17 ? 233 ASN A OD1 1 ATOM 356 N ND2 . ASN A 1 48 ? -37.587 -34.406 11.580 1.00 80.19 ? 233 ASN A ND2 1 ATOM 357 N N . PRO A 1 49 ? -40.816 -31.045 9.421 1.00 79.03 ? 234 PRO A N 1 ATOM 358 C CA . PRO A 1 49 ? -42.249 -31.083 9.683 1.00 78.79 ? 234 PRO A CA 1 ATOM 359 C C . PRO A 1 49 ? -42.833 -32.489 9.606 1.00 78.49 ? 234 PRO A C 1 ATOM 360 O O . PRO A 1 49 ? -42.518 -33.243 8.685 1.00 78.42 ? 234 PRO A O 1 ATOM 361 C CB . PRO A 1 49 ? -42.819 -30.214 8.565 1.00 78.52 ? 234 PRO A CB 1 ATOM 362 C CG . PRO A 1 49 ? -41.888 -30.430 7.424 1.00 78.58 ? 234 PRO A CG 1 ATOM 363 C CD . PRO A 1 49 ? -40.529 -30.728 8.009 1.00 78.53 ? 234 PRO A CD 1 ATOM 364 N N . THR A 1 50 ? -43.672 -32.831 10.580 1.00 78.36 ? 235 THR A N 1 ATOM 365 C CA . THR A 1 50 ? -44.465 -34.052 10.525 1.00 78.03 ? 235 THR A CA 1 ATOM 366 C C . THR A 1 50 ? -45.670 -33.786 9.627 1.00 77.43 ? 235 THR A C 1 ATOM 367 O O . THR A 1 50 ? -46.539 -32.983 9.970 1.00 76.65 ? 235 THR A O 1 ATOM 368 C CB . THR A 1 50 ? -44.941 -34.477 11.924 1.00 78.01 ? 235 THR A CB 1 ATOM 369 O OG1 . THR A 1 50 ? -45.681 -33.408 12.525 1.00 78.14 ? 235 THR A OG1 1 ATOM 370 C CG2 . THR A 1 50 ? -43.752 -34.828 12.812 1.00 78.02 ? 235 THR A CG2 1 ATOM 371 N N . VAL A 1 51 ? -45.706 -34.452 8.474 1.00 77.66 ? 236 VAL A N 1 ATOM 372 C CA . VAL A 1 51 ? -46.690 -34.154 7.433 1.00 77.60 ? 236 VAL A CA 1 ATOM 373 C C . VAL A 1 51 ? -47.888 -35.104 7.484 1.00 77.53 ? 236 VAL A C 1 ATOM 374 O O . VAL A 1 51 ? -47.725 -36.324 7.432 1.00 76.72 ? 236 VAL A O 1 ATOM 375 C CB . VAL A 1 51 ? -46.054 -34.231 6.029 1.00 76.76 ? 236 VAL A CB 1 ATOM 376 C CG1 . VAL A 1 51 ? -47.076 -33.877 4.960 1.00 76.86 ? 236 VAL A CG1 1 ATOM 377 C CG2 . VAL A 1 51 ? -44.849 -33.307 5.943 1.00 76.11 ? 236 VAL A CG2 1 ATOM 378 N N . THR A 1 52 ? -49.085 -34.526 7.591 1.00 78.22 ? 237 THR A N 1 ATOM 379 C CA . THR A 1 52 ? -50.337 -35.272 7.477 1.00 77.87 ? 237 THR A CA 1 ATOM 380 C C . THR A 1 52 ? -50.844 -35.162 6.045 1.00 77.58 ? 237 THR A C 1 ATOM 381 O O . THR A 1 52 ? -50.890 -34.069 5.486 1.00 77.56 ? 237 THR A O 1 ATOM 382 C CB . THR A 1 52 ? -51.416 -34.717 8.429 1.00 78.56 ? 237 THR A CB 1 ATOM 383 O OG1 . THR A 1 52 ? -50.996 -34.887 9.789 1.00 78.88 ? 237 THR A OG1 1 ATOM 384 C CG2 . THR A 1 52 ? -52.746 -35.437 8.219 1.00 78.78 ? 237 THR A CG2 1 ATOM 385 N N . TYR A 1 53 ? -51.230 -36.294 5.462 1.00 77.59 ? 238 TYR A N 1 ATOM 386 C CA . TYR A 1 53 ? -51.642 -36.347 4.060 1.00 77.48 ? 238 TYR A CA 1 ATOM 387 C C . TYR A 1 53 ? -53.135 -36.616 3.898 1.00 77.24 ? 238 TYR A C 1 ATOM 388 O O . TYR A 1 53 ? -53.740 -37.341 4.690 1.00 77.84 ? 238 TYR A O 1 ATOM 389 C CB . TYR A 1 53 ? -50.868 -37.444 3.324 1.00 78.07 ? 238 TYR A CB 1 ATOM 390 C CG . TYR A 1 53 ? -49.415 -37.123 3.070 1.00 78.13 ? 238 TYR A CG 1 ATOM 391 C CD1 . TYR A 1 53 ? -49.052 -36.148 2.149 1.00 78.26 ? 238 TYR A CD1 1 ATOM 392 C CD2 . TYR A 1 53 ? -48.400 -37.808 3.734 1.00 78.15 ? 238 TYR A CD2 1 ATOM 393 C CE1 . TYR A 1 53 ? -47.719 -35.851 1.904 1.00 78.38 ? 238 TYR A CE1 1 ATOM 394 C CE2 . TYR A 1 53 ? -47.063 -37.520 3.495 1.00 78.12 ? 238 TYR A CE2 1 ATOM 395 C CZ . TYR A 1 53 ? -46.730 -36.541 2.579 1.00 78.28 ? 238 TYR A CZ 1 ATOM 396 O OH . TYR A 1 53 ? -45.408 -36.251 2.333 1.00 78.30 ? 238 TYR A OH 1 ATOM 397 N N . GLY A 1 54 ? -53.717 -36.008 2.869 1.00 76.88 ? 239 GLY A N 1 ATOM 398 C CA . GLY A 1 54 ? -55.007 -36.426 2.331 1.00 76.79 ? 239 GLY A CA 1 ATOM 399 C C . GLY A 1 54 ? -54.748 -37.037 0.969 1.00 76.69 ? 239 GLY A C 1 ATOM 400 O O . GLY A 1 54 ? -53.592 -37.219 0.583 1.00 77.51 ? 239 GLY A O 1 ATOM 401 N N . ASN A 1 55 ? -55.807 -37.354 0.231 1.00 76.40 ? 240 ASN A N 1 ATOM 402 C CA . ASN A 1 55 ? -55.642 -37.863 -1.132 1.00 76.82 ? 240 ASN A CA 1 ATOM 403 C C . ASN A 1 55 ? -55.233 -36.769 -2.114 1.00 77.82 ? 240 ASN A C 1 ATOM 404 O O . ASN A 1 55 ? -54.691 -37.055 -3.182 1.00 77.89 ? 240 ASN A O 1 ATOM 405 C CB . ASN A 1 55 ? -56.912 -38.567 -1.624 1.00 76.69 ? 240 ASN A CB 1 ATOM 406 C CG . ASN A 1 55 ? -58.109 -37.630 -1.762 1.00 76.77 ? 240 ASN A CG 1 ATOM 407 O OD1 . ASN A 1 55 ? -58.202 -36.603 -1.086 1.00 74.93 ? 240 ASN A OD1 1 ATOM 408 N ND2 . ASN A 1 55 ? -59.036 -38.002 -2.653 1.00 79.38 ? 240 ASN A ND2 1 ATOM 409 N N . ASP A 1 56 ? -55.485 -35.519 -1.731 1.00 78.63 ? 241 ASP A N 1 ATOM 410 C CA . ASP A 1 56 ? -55.347 -34.375 -2.622 1.00 76.96 ? 241 ASP A CA 1 ATOM 411 C C . ASP A 1 56 ? -54.598 -33.210 -1.951 1.00 75.96 ? 241 ASP A C 1 ATOM 412 O O . ASP A 1 56 ? -54.557 -32.105 -2.492 1.00 75.65 ? 241 ASP A O 1 ATOM 413 C CB . ASP A 1 56 ? -56.759 -33.937 -3.031 1.00 78.51 ? 241 ASP A CB 1 ATOM 414 C CG . ASP A 1 56 ? -56.771 -32.882 -4.119 1.00 80.28 ? 241 ASP A CG 1 ATOM 415 O OD1 . ASP A 1 56 ? -55.924 -32.947 -5.036 1.00 82.59 ? 241 ASP A OD1 1 ATOM 416 O OD2 . ASP A 1 56 ? -57.654 -31.995 -4.065 1.00 80.56 ? 241 ASP A OD2 1 ATOM 417 N N . SER A 1 57 ? -53.988 -33.465 -0.790 1.00 75.60 ? 242 SER A N 1 ATOM 418 C CA . SER A 1 57 ? -53.470 -32.385 0.059 1.00 75.38 ? 242 SER A CA 1 ATOM 419 C C . SER A 1 57 ? -52.413 -32.846 1.062 1.00 73.67 ? 242 SER A C 1 ATOM 420 O O . SER A 1 57 ? -52.195 -34.045 1.247 1.00 72.51 ? 242 SER A O 1 ATOM 421 C CB . SER A 1 57 ? -54.625 -31.738 0.824 1.00 76.02 ? 242 SER A CB 1 ATOM 422 O OG . SER A 1 57 ? -55.293 -32.689 1.637 1.00 76.55 ? 242 SER A OG 1 ATOM 423 N N . PHE A 1 58 ? -51.762 -31.874 1.701 1.00 73.48 ? 243 PHE A N 1 ATOM 424 C CA . PHE A 1 58 ? -50.843 -32.141 2.808 1.00 74.87 ? 243 PHE A CA 1 ATOM 425 C C . PHE A 1 58 ? -50.948 -31.056 3.879 1.00 75.17 ? 243 PHE A C 1 ATOM 426 O O . PHE A 1 58 ? -51.293 -29.912 3.584 1.00 75.76 ? 243 PHE A O 1 ATOM 427 C CB . PHE A 1 58 ? -49.393 -32.247 2.310 1.00 76.04 ? 243 PHE A CB 1 ATOM 428 C CG . PHE A 1 58 ? -48.726 -30.915 2.065 1.00 76.02 ? 243 PHE A CG 1 ATOM 429 C CD1 . PHE A 1 58 ? -48.130 -30.218 3.108 1.00 75.97 ? 243 PHE A CD1 1 ATOM 430 C CD2 . PHE A 1 58 ? -48.685 -30.368 0.790 1.00 76.37 ? 243 PHE A CD2 1 ATOM 431 C CE1 . PHE A 1 58 ? -47.518 -28.993 2.886 1.00 76.12 ? 243 PHE A CE1 1 ATOM 432 C CE2 . PHE A 1 58 ? -48.071 -29.144 0.562 1.00 76.36 ? 243 PHE A CE2 1 ATOM 433 C CZ . PHE A 1 58 ? -47.488 -28.456 1.613 1.00 76.19 ? 243 PHE A CZ 1 ATOM 434 N N . SER A 1 59 ? -50.640 -31.431 5.119 1.00 74.97 ? 244 SER A N 1 ATOM 435 C CA . SER A 1 59 ? -50.567 -30.487 6.233 1.00 74.72 ? 244 SER A CA 1 ATOM 436 C C . SER A 1 59 ? -49.269 -30.733 6.999 1.00 74.25 ? 244 SER A C 1 ATOM 437 O O . SER A 1 59 ? -49.111 -31.770 7.643 1.00 73.84 ? 244 SER A O 1 ATOM 438 C CB . SER A 1 59 ? -51.774 -30.658 7.159 1.00 74.76 ? 244 SER A CB 1 ATOM 439 O OG . SER A 1 59 ? -51.762 -29.698 8.201 1.00 74.77 ? 244 SER A OG 1 ATOM 440 N N . ALA A 1 60 ? -48.344 -29.777 6.916 1.00 74.36 ? 245 ALA A N 1 ATOM 441 C CA . ALA A 1 60 ? -47.005 -29.924 7.493 1.00 74.70 ? 245 ALA A CA 1 ATOM 442 C C . ALA A 1 60 ? -46.842 -29.057 8.740 1.00 74.84 ? 245 ALA A C 1 ATOM 443 O O . ALA A 1 60 ? -46.739 -27.835 8.641 1.00 74.73 ? 245 ALA A O 1 ATOM 444 C CB . ALA A 1 60 ? -45.946 -29.561 6.456 1.00 73.67 ? 245 ALA A CB 1 ATOM 445 N N . LYS A 1 61 ? -46.809 -29.702 9.905 1.00 75.02 ? 246 LYS A N 1 ATOM 446 C CA . LYS A 1 61 ? -46.659 -29.018 11.190 1.00 75.24 ? 246 LYS A CA 1 ATOM 447 C C . LYS A 1 61 ? -45.264 -29.285 11.745 1.00 75.42 ? 246 LYS A C 1 ATOM 448 O O . LYS A 1 61 ? -44.827 -30.435 11.794 1.00 76.10 ? 246 LYS A O 1 ATOM 449 C CB . LYS A 1 61 ? -47.716 -29.528 12.172 1.00 75.52 ? 246 LYS A CB 1 ATOM 450 C CG . LYS A 1 61 ? -47.886 -28.685 13.425 1.00 75.48 ? 246 LYS A CG 1 ATOM 451 C CD . LYS A 1 61 ? -48.993 -29.250 14.312 1.00 75.66 ? 246 LYS A CD 1 ATOM 452 C CE . LYS A 1 61 ? -49.327 -28.316 15.471 1.00 75.75 ? 246 LYS A CE 1 ATOM 453 N NZ . LYS A 1 61 ? -50.254 -28.946 16.459 1.00 75.53 ? 246 LYS A NZ 1 ATOM 454 N N . ALA A 1 62 ? -44.570 -28.228 12.165 1.00 75.22 ? 247 ALA A N 1 ATOM 455 C CA . ALA A 1 62 ? -43.190 -28.356 12.642 1.00 75.75 ? 247 ALA A CA 1 ATOM 456 C C . ALA A 1 62 ? -42.869 -27.377 13.766 1.00 75.96 ? 247 ALA A C 1 ATOM 457 O O . ALA A 1 62 ? -43.209 -26.196 13.686 1.00 75.95 ? 247 ALA A O 1 ATOM 458 C CB . ALA A 1 62 ? -42.223 -28.151 11.490 1.00 75.94 ? 247 ALA A CB 1 ATOM 459 N N . SER A 1 63 ? -42.210 -27.878 14.810 1.00 76.43 ? 248 SER A N 1 ATOM 460 C CA . SER A 1 63 ? -41.661 -27.023 15.860 1.00 76.54 ? 248 SER A CA 1 ATOM 461 C C . SER A 1 63 ? -40.377 -26.375 15.370 1.00 77.37 ? 248 SER A C 1 ATOM 462 O O . SER A 1 63 ? -39.735 -26.876 14.445 1.00 78.48 ? 248 SER A O 1 ATOM 463 C CB . SER A 1 63 ? -41.381 -27.823 17.134 1.00 76.36 ? 248 SER A CB 1 ATOM 464 O OG . SER A 1 63 ? -42.579 -28.096 17.837 1.00 76.65 ? 248 SER A OG 1 ATOM 465 N N . VAL A 1 64 ? -40.008 -25.260 15.990 1.00 77.38 ? 249 VAL A N 1 ATOM 466 C CA . VAL A 1 64 ? -38.797 -24.537 15.615 1.00 77.20 ? 249 VAL A CA 1 ATOM 467 C C . VAL A 1 64 ? -38.204 -23.816 16.822 1.00 77.12 ? 249 VAL A C 1 ATOM 468 O O . VAL A 1 64 ? -38.774 -22.843 17.315 1.00 76.92 ? 249 VAL A O 1 ATOM 469 C CB . VAL A 1 64 ? -39.074 -23.522 14.475 1.00 77.22 ? 249 VAL A CB 1 ATOM 470 C CG1 . VAL A 1 64 ? -40.261 -22.630 14.816 1.00 77.12 ? 249 VAL A CG1 1 ATOM 471 C CG2 . VAL A 1 64 ? -37.828 -22.690 14.177 1.00 77.31 ? 249 VAL A CG2 1 ATOM 472 N N . SER A 1 65 ? -37.065 -24.316 17.300 1.00 77.46 ? 250 SER A N 1 ATOM 473 C CA . SER A 1 65 ? -36.326 -23.669 18.381 1.00 77.76 ? 250 SER A CA 1 ATOM 474 C C . SER A 1 65 ? -35.449 -22.556 17.817 1.00 77.99 ? 250 SER A C 1 ATOM 475 O O . SER A 1 65 ? -34.953 -22.658 16.695 1.00 78.79 ? 250 SER A O 1 ATOM 476 C CB . SER A 1 65 ? -35.458 -24.686 19.122 1.00 79.09 ? 250 SER A CB 1 ATOM 477 O OG . SER A 1 65 ? -36.252 -25.705 19.705 1.00 80.40 ? 250 SER A OG 1 ATOM 478 N N . VAL A 1 66 ? -35.263 -21.497 18.600 1.00 77.71 ? 251 VAL A N 1 ATOM 479 C CA . VAL A 1 66 ? -34.428 -20.368 18.191 1.00 77.33 ? 251 VAL A CA 1 ATOM 480 C C . VAL A 1 66 ? -33.496 -19.949 19.325 1.00 76.97 ? 251 VAL A C 1 ATOM 481 O O . VAL A 1 66 ? -33.861 -20.029 20.498 1.00 76.89 ? 251 VAL A O 1 ATOM 482 C CB . VAL A 1 66 ? -35.285 -19.161 17.749 1.00 77.17 ? 251 VAL A CB 1 ATOM 483 C CG1 . VAL A 1 66 ? -36.041 -19.490 16.477 1.00 77.20 ? 251 VAL A CG1 1 ATOM 484 C CG2 . VAL A 1 66 ? -36.249 -18.748 18.851 1.00 76.97 ? 251 VAL A CG2 1 ATOM 485 N N . THR A 1 67 ? -32.292 -19.512 18.962 1.00 77.10 ? 252 THR A N 1 ATOM 486 C CA . THR A 1 67 ? -31.280 -19.090 19.934 1.00 77.24 ? 252 THR A CA 1 ATOM 487 C C . THR A 1 67 ? -30.803 -17.672 19.604 1.00 77.14 ? 252 THR A C 1 ATOM 488 O O . THR A 1 67 ? -31.366 -17.014 18.730 1.00 77.28 ? 252 THR A O 1 ATOM 489 C CB . THR A 1 67 ? -30.079 -20.064 19.942 1.00 77.27 ? 252 THR A CB 1 ATOM 490 O OG1 . THR A 1 67 ? -29.387 -19.993 18.689 1.00 77.49 ? 252 THR A OG1 1 ATOM 491 C CG2 . THR A 1 67 ? -30.549 -21.494 20.180 1.00 77.17 ? 252 THR A CG2 1 ATOM 492 N N . ALA A 1 68 ? -29.773 -17.206 20.308 1.00 77.10 ? 253 ALA A N 1 ATOM 493 C CA . ALA A 1 68 ? -29.175 -15.894 20.040 1.00 77.26 ? 253 ALA A CA 1 ATOM 494 C C . ALA A 1 68 ? -28.636 -15.780 18.608 1.00 77.53 ? 253 ALA A C 1 ATOM 495 O O . ALA A 1 68 ? -28.602 -14.687 18.038 1.00 77.40 ? 253 ALA A O 1 ATOM 496 C CB . ALA A 1 68 ? -28.067 -15.608 21.041 1.00 76.95 ? 253 ALA A CB 1 ATOM 497 N N . GLU A 1 69 ? -28.222 -16.909 18.035 1.00 77.74 ? 254 GLU A N 1 ATOM 498 C CA . GLU A 1 69 ? -27.724 -16.948 16.657 1.00 77.83 ? 254 GLU A CA 1 ATOM 499 C C . GLU A 1 69 ? -28.818 -16.695 15.615 1.00 77.13 ? 254 GLU A C 1 ATOM 500 O O . GLU A 1 69 ? -28.514 -16.431 14.455 1.00 76.71 ? 254 GLU A O 1 ATOM 501 C CB . GLU A 1 69 ? -27.052 -18.295 16.370 1.00 78.41 ? 254 GLU A CB 1 ATOM 502 C CG . GLU A 1 69 ? -25.809 -18.561 17.214 1.00 79.01 ? 254 GLU A CG 1 ATOM 503 C CD . GLU A 1 69 ? -25.021 -19.777 16.746 1.00 78.94 ? 254 GLU A CD 1 ATOM 504 O OE1 . GLU A 1 69 ? -25.546 -20.559 15.921 1.00 79.35 ? 254 GLU A OE1 1 ATOM 505 O OE2 . GLU A 1 69 ? -23.871 -19.950 17.209 1.00 78.80 ? 254 GLU A OE2 1 ATOM 506 N N . ASP A 1 70 ? -30.081 -16.792 16.025 1.00 77.20 ? 255 ASP A N 1 ATOM 507 C CA . ASP A 1 70 ? -31.212 -16.540 15.133 1.00 77.61 ? 255 ASP A CA 1 ATOM 508 C C . ASP A 1 70 ? -31.774 -15.125 15.279 1.00 77.26 ? 255 ASP A C 1 ATOM 509 O O . ASP A 1 70 ? -32.607 -14.708 14.474 1.00 77.17 ? 255 ASP A O 1 ATOM 510 C CB . ASP A 1 70 ? -32.329 -17.556 15.397 1.00 78.19 ? 255 ASP A CB 1 ATOM 511 C CG . ASP A 1 70 ? -31.902 -18.988 15.116 1.00 78.60 ? 255 ASP A CG 1 ATOM 512 O OD1 . ASP A 1 70 ? -30.698 -19.225 14.884 1.00 78.93 ? 255 ASP A OD1 1 ATOM 513 O OD2 . ASP A 1 70 ? -32.777 -19.880 15.129 1.00 78.74 ? 255 ASP A OD2 1 ATOM 514 N N . GLU A 1 71 ? -31.320 -14.390 16.294 1.00 77.67 ? 256 GLU A N 1 ATOM 515 C CA . GLU A 1 71 ? -31.891 -13.075 16.611 1.00 77.94 ? 256 GLU A CA 1 ATOM 516 C C . GLU A 1 71 ? -31.867 -12.139 15.400 1.00 77.87 ? 256 GLU A C 1 ATOM 517 O O . GLU A 1 71 ? -30.872 -12.068 14.675 1.00 77.86 ? 256 GLU A O 1 ATOM 518 C CB . GLU A 1 71 ? -31.159 -12.428 17.794 1.00 77.74 ? 256 GLU A CB 1 ATOM 519 C CG . GLU A 1 71 ? -31.934 -11.280 18.442 1.00 78.07 ? 256 GLU A CG 1 ATOM 520 C CD . GLU A 1 71 ? -31.188 -10.618 19.597 1.00 78.87 ? 256 GLU A CD 1 ATOM 521 O OE1 . GLU A 1 71 ? -31.682 -9.587 20.103 1.00 79.14 ? 256 GLU A OE1 1 ATOM 522 O OE2 . GLU A 1 71 ? -30.112 -11.117 19.998 1.00 79.54 ? 256 GLU A OE2 1 ATOM 523 N N . GLY A 1 72 ? -32.975 -11.428 15.196 1.00 77.87 ? 257 GLY A N 1 ATOM 524 C CA . GLY A 1 72 ? -33.152 -10.555 14.039 1.00 78.15 ? 257 GLY A CA 1 ATOM 525 C C . GLY A 1 72 ? -34.345 -10.995 13.213 1.00 78.42 ? 257 GLY A C 1 ATOM 526 O O . GLY A 1 72 ? -35.107 -11.870 13.626 1.00 78.34 ? 257 GLY A O 1 ATOM 527 N N . THR A 1 73 ? -34.506 -10.384 12.043 1.00 78.96 ? 258 THR A N 1 ATOM 528 C CA . THR A 1 73 ? -35.591 -10.735 11.131 1.00 79.10 ? 258 THR A CA 1 ATOM 529 C C . THR A 1 73 ? -35.184 -11.911 10.250 1.00 79.33 ? 258 THR A C 1 ATOM 530 O O . THR A 1 73 ? -34.396 -11.750 9.318 1.00 79.58 ? 258 THR A O 1 ATOM 531 C CB . THR A 1 73 ? -35.982 -9.542 10.233 1.00 78.97 ? 258 THR A CB 1 ATOM 532 O OG1 . THR A 1 73 ? -36.523 -8.491 11.041 1.00 79.13 ? 258 THR A OG1 1 ATOM 533 C CG2 . THR A 1 73 ? -37.017 -9.960 9.200 1.00 79.02 ? 258 THR A CG2 1 ATOM 534 N N . GLN A 1 74 ? -35.716 -13.091 10.559 1.00 79.49 ? 259 GLN A N 1 ATOM 535 C CA . GLN A 1 74 ? -35.512 -14.278 9.731 1.00 79.98 ? 259 GLN A CA 1 ATOM 536 C C . GLN A 1 74 ? -36.693 -14.462 8.783 1.00 80.21 ? 259 GLN A C 1 ATOM 537 O O . GLN A 1 74 ? -37.766 -13.892 8.996 1.00 80.05 ? 259 GLN A O 1 ATOM 538 C CB . GLN A 1 74 ? -35.354 -15.525 10.605 1.00 80.53 ? 259 GLN A CB 1 ATOM 539 C CG . GLN A 1 74 ? -34.175 -15.477 11.574 1.00 81.10 ? 259 GLN A CG 1 ATOM 540 C CD . GLN A 1 74 ? -32.826 -15.431 10.879 1.00 81.83 ? 259 GLN A CD 1 ATOM 541 O OE1 . GLN A 1 74 ? -32.700 -15.784 9.705 1.00 82.13 ? 259 GLN A OE1 1 ATOM 542 N NE2 . GLN A 1 74 ? -31.805 -14.998 11.608 1.00 82.30 ? 259 GLN A NE2 1 ATOM 543 N N . ARG A 1 75 ? -36.487 -15.260 7.740 1.00 80.48 ? 260 ARG A N 1 ATOM 544 C CA . ARG A 1 75 ? -37.519 -15.511 6.739 1.00 80.80 ? 260 ARG A CA 1 ATOM 545 C C . ARG A 1 75 ? -38.028 -16.946 6.818 1.00 80.57 ? 260 ARG A C 1 ATOM 546 O O . ARG A 1 75 ? -37.298 -17.891 6.511 1.00 80.76 ? 260 ARG A O 1 ATOM 547 C CB . ARG A 1 75 ? -36.974 -15.246 5.337 1.00 81.20 ? 260 ARG A CB 1 ATOM 548 C CG . ARG A 1 75 ? -36.507 -13.815 5.106 1.00 82.06 ? 260 ARG A CG 1 ATOM 549 C CD . ARG A 1 75 ? -36.653 -13.411 3.644 1.00 82.73 ? 260 ARG A CD 1 ATOM 550 N NE . ARG A 1 75 ? -36.162 -14.443 2.730 1.00 83.56 ? 260 ARG A NE 1 ATOM 551 C CZ . ARG A 1 75 ? -36.361 -14.444 1.412 1.00 84.20 ? 260 ARG A CZ 1 ATOM 552 N NH1 . ARG A 1 75 ? -37.038 -13.459 0.821 1.00 84.39 ? 260 ARG A NH1 1 ATOM 553 N NH2 . ARG A 1 75 ? -35.875 -15.436 0.675 1.00 84.06 ? 260 ARG A NH2 1 ATOM 554 N N . LEU A 1 76 ? -39.282 -17.104 7.229 1.00 80.13 ? 261 LEU A N 1 ATOM 555 C CA . LEU A 1 76 ? -39.937 -18.406 7.211 1.00 80.13 ? 261 LEU A CA 1 ATOM 556 C C . LEU A 1 76 ? -40.481 -18.654 5.814 1.00 80.02 ? 261 LEU A C 1 ATOM 557 O O . LEU A 1 76 ? -41.237 -17.838 5.287 1.00 80.00 ? 261 LEU A O 1 ATOM 558 C CB . LEU A 1 76 ? -41.076 -18.455 8.230 1.00 79.85 ? 261 LEU A CB 1 ATOM 559 C CG . LEU A 1 76 ? -41.723 -19.826 8.435 1.00 79.93 ? 261 LEU A CG 1 ATOM 560 C CD1 . LEU A 1 76 ? -40.731 -20.814 9.031 1.00 80.02 ? 261 LEU A CD1 1 ATOM 561 C CD2 . LEU A 1 76 ? -42.940 -19.700 9.319 1.00 79.98 ? 261 LEU A CD2 1 ATOM 562 N N . THR A 1 77 ? -40.092 -19.778 5.218 1.00 80.04 ? 262 THR A N 1 ATOM 563 C CA . THR A 1 77 ? -40.512 -20.118 3.863 1.00 80.16 ? 262 THR A CA 1 ATOM 564 C C . THR A 1 77 ? -41.034 -21.547 3.778 1.00 80.38 ? 262 THR A C 1 ATOM 565 O O . THR A 1 77 ? -40.554 -22.438 4.481 1.00 80.03 ? 262 THR A O 1 ATOM 566 C CB . THR A 1 77 ? -39.359 -19.949 2.857 1.00 79.81 ? 262 THR A CB 1 ATOM 567 O OG1 . THR A 1 77 ? -38.221 -20.702 3.294 1.00 79.58 ? 262 THR A OG1 1 ATOM 568 C CG2 . THR A 1 77 ? -38.978 -18.484 2.728 1.00 79.99 ? 262 THR A CG2 1 ATOM 569 N N . CYS A 1 78 ? -42.021 -21.750 2.909 1.00 81.28 ? 263 CYS A N 1 ATOM 570 C CA . CYS A 1 78 ? -42.593 -23.068 2.668 1.00 80.62 ? 263 CYS A CA 1 ATOM 571 C C . CYS A 1 78 ? -42.687 -23.334 1.169 1.00 80.53 ? 263 CYS A C 1 ATOM 572 O O . CYS A 1 78 ? -43.621 -22.882 0.509 1.00 80.62 ? 263 CYS A O 1 ATOM 573 C CB . CYS A 1 78 ? -43.978 -23.170 3.303 1.00 81.53 ? 263 CYS A CB 1 ATOM 574 S SG . CYS A 1 78 ? -44.727 -24.801 3.133 1.00 82.73 ? 263 CYS A SG 1 ATOM 575 N N . ALA A 1 79 ? -41.708 -24.063 0.641 1.00 80.35 ? 264 ALA A N 1 ATOM 576 C CA . ALA A 1 79 ? -41.671 -24.407 -0.777 1.00 79.63 ? 264 ALA A CA 1 ATOM 577 C C . ALA A 1 79 ? -42.321 -25.766 -1.015 1.00 79.34 ? 264 ALA A C 1 ATOM 578 O O . ALA A 1 79 ? -42.182 -26.682 -0.204 1.00 79.74 ? 264 ALA A O 1 ATOM 579 C CB . ALA A 1 79 ? -40.237 -24.420 -1.276 1.00 79.60 ? 264 ALA A CB 1 ATOM 580 N N . VAL A 1 80 ? -43.038 -25.881 -2.126 1.00 78.89 ? 265 VAL A N 1 ATOM 581 C CA . VAL A 1 80 ? -43.613 -27.150 -2.554 1.00 78.64 ? 265 VAL A CA 1 ATOM 582 C C . VAL A 1 80 ? -43.295 -27.363 -4.027 1.00 78.62 ? 265 VAL A C 1 ATOM 583 O O . VAL A 1 80 ? -43.754 -26.600 -4.876 1.00 78.71 ? 265 VAL A O 1 ATOM 584 C CB . VAL A 1 80 ? -45.138 -27.170 -2.371 1.00 78.20 ? 265 VAL A CB 1 ATOM 585 C CG1 . VAL A 1 80 ? -45.704 -28.514 -2.800 1.00 77.99 ? 265 VAL A CG1 1 ATOM 586 C CG2 . VAL A 1 80 ? -45.505 -26.872 -0.929 1.00 78.62 ? 265 VAL A CG2 1 ATOM 587 N N . ILE A 1 81 ? -42.492 -28.382 -4.324 1.00 78.34 ? 266 ILE A N 1 ATOM 588 C CA . ILE A 1 81 ? -42.205 -28.755 -5.705 1.00 78.61 ? 266 ILE A CA 1 ATOM 589 C C . ILE A 1 81 ? -42.922 -30.062 -6.038 1.00 78.37 ? 266 ILE A C 1 ATOM 590 O O . ILE A 1 81 ? -42.899 -31.012 -5.253 1.00 77.92 ? 266 ILE A O 1 ATOM 591 C CB . ILE A 1 81 ? -40.672 -28.868 -5.984 1.00 79.06 ? 266 ILE A CB 1 ATOM 592 C CG1 . ILE A 1 81 ? -40.080 -30.153 -5.398 1.00 79.17 ? 266 ILE A CG1 1 ATOM 593 C CG2 . ILE A 1 81 ? -39.940 -27.648 -5.431 1.00 79.27 ? 266 ILE A CG2 1 ATOM 594 C CD1 . ILE A 1 81 ? -38.563 -30.181 -5.389 1.00 78.99 ? 266 ILE A CD1 1 ATOM 595 N N . LEU A 1 82 ? -43.586 -30.085 -7.192 1.00 78.46 ? 267 LEU A N 1 ATOM 596 C CA . LEU A 1 82 ? -44.253 -31.283 -7.690 1.00 78.49 ? 267 LEU A CA 1 ATOM 597 C C . LEU A 1 82 ? -43.849 -31.498 -9.145 1.00 77.94 ? 267 LEU A C 1 ATOM 598 O O . LEU A 1 82 ? -44.541 -31.068 -10.070 1.00 76.82 ? 267 LEU A O 1 ATOM 599 C CB . LEU A 1 82 ? -45.773 -31.148 -7.554 1.00 78.24 ? 267 LEU A CB 1 ATOM 600 C CG . LEU A 1 82 ? -46.631 -32.327 -8.026 1.00 78.23 ? 267 LEU A CG 1 ATOM 601 C CD1 . LEU A 1 82 ? -46.172 -33.632 -7.394 1.00 78.20 ? 267 LEU A CD1 1 ATOM 602 C CD2 . LEU A 1 82 ? -48.097 -32.069 -7.716 1.00 78.39 ? 267 LEU A CD2 1 ATOM 603 N N . GLY A 1 83 ? -42.707 -32.153 -9.333 1.00 78.58 ? 268 GLY A N 1 ATOM 604 C CA . GLY A 1 83 ? -42.152 -32.375 -10.659 1.00 79.34 ? 268 GLY A CA 1 ATOM 605 C C . GLY A 1 83 ? -41.550 -31.102 -11.218 1.00 79.29 ? 268 GLY A C 1 ATOM 606 O O . GLY A 1 83 ? -40.575 -30.580 -10.678 1.00 78.68 ? 268 GLY A O 1 ATOM 607 N N . ASN A 1 84 ? -42.147 -30.596 -12.293 1.00 80.23 ? 269 ASN A N 1 ATOM 608 C CA . ASN A 1 84 ? -41.628 -29.427 -12.999 1.00 81.45 ? 269 ASN A CA 1 ATOM 609 C C . ASN A 1 84 ? -42.126 -28.104 -12.423 1.00 80.36 ? 269 ASN A C 1 ATOM 610 O O . ASN A 1 84 ? -41.464 -27.074 -12.565 1.00 80.57 ? 269 ASN A O 1 ATOM 611 C CB . ASN A 1 84 ? -41.986 -29.520 -14.485 1.00 83.48 ? 269 ASN A CB 1 ATOM 612 C CG . ASN A 1 84 ? -41.350 -30.735 -15.165 1.00 85.53 ? 269 ASN A CG 1 ATOM 613 O OD1 . ASN A 1 84 ? -40.467 -31.370 -14.583 1.00 86.01 ? 269 ASN A OD1 1 ATOM 614 N ND2 . ASN A 1 84 ? -41.786 -31.073 -16.392 1.00 86.61 ? 269 ASN A ND2 1 ATOM 615 N N . GLN A 1 85 ? -43.288 -28.133 -11.775 1.00 79.33 ? 270 GLN A N 1 ATOM 616 C CA . GLN A 1 85 ? -43.872 -26.931 -11.187 1.00 78.82 ? 270 GLN A CA 1 ATOM 617 C C . GLN A 1 85 ? -43.468 -26.774 -9.727 1.00 77.85 ? 270 GLN A C 1 ATOM 618 O O . GLN A 1 85 ? -42.966 -27.708 -9.103 1.00 77.69 ? 270 GLN A O 1 ATOM 619 C CB . GLN A 1 85 ? -45.396 -26.953 -11.315 1.00 78.62 ? 270 GLN A CB 1 ATOM 620 C CG . GLN A 1 85 ? -45.886 -26.727 -12.734 1.00 78.93 ? 270 GLN A CG 1 ATOM 621 C CD . GLN A 1 85 ? -47.392 -26.581 -12.816 1.00 79.25 ? 270 GLN A CD 1 ATOM 622 O OE1 . GLN A 1 85 ? -48.139 -27.346 -12.202 1.00 79.33 ? 270 GLN A OE1 1 ATOM 623 N NE2 . GLN A 1 85 ? -47.847 -25.595 -13.581 1.00 79.67 ? 270 GLN A NE2 1 ATOM 624 N N . SER A 1 86 ? -43.694 -25.579 -9.192 1.00 77.39 ? 271 SER A N 1 ATOM 625 C CA . SER A 1 86 ? -43.277 -25.244 -7.839 1.00 77.19 ? 271 SER A CA 1 ATOM 626 C C . SER A 1 86 ? -44.018 -24.009 -7.338 1.00 76.69 ? 271 SER A C 1 ATOM 627 O O . SER A 1 86 ? -44.168 -23.028 -8.067 1.00 76.59 ? 271 SER A O 1 ATOM 628 C CB . SER A 1 86 ? -41.769 -24.987 -7.804 1.00 76.93 ? 271 SER A CB 1 ATOM 629 O OG . SER A 1 86 ? -41.351 -24.542 -6.527 1.00 76.96 ? 271 SER A OG 1 ATOM 630 N N . GLN A 1 87 ? -44.485 -24.070 -6.095 1.00 76.25 ? 272 GLN A N 1 ATOM 631 C CA . GLN A 1 87 ? -45.117 -22.929 -5.444 1.00 76.63 ? 272 GLN A CA 1 ATOM 632 C C . GLN A 1 87 ? -44.524 -22.780 -4.055 1.00 76.51 ? 272 GLN A C 1 ATOM 633 O O . GLN A 1 87 ? -44.362 -23.768 -3.341 1.00 76.69 ? 272 GLN A O 1 ATOM 634 C CB . GLN A 1 87 ? -46.631 -23.130 -5.354 1.00 76.71 ? 272 GLN A CB 1 ATOM 635 C CG . GLN A 1 87 ? -47.366 -23.015 -6.690 1.00 77.06 ? 272 GLN A CG 1 ATOM 636 C CD . GLN A 1 87 ? -47.457 -21.583 -7.202 1.00 77.44 ? 272 GLN A CD 1 ATOM 637 O OE1 . GLN A 1 87 ? -47.618 -20.639 -6.426 1.00 77.68 ? 272 GLN A OE1 1 ATOM 638 N NE2 . GLN A 1 87 ? -47.364 -21.418 -8.519 1.00 77.17 ? 272 GLN A NE2 1 ATOM 639 N N . GLU A 1 88 ? -44.195 -21.547 -3.680 1.00 76.84 ? 273 GLU A N 1 ATOM 640 C CA . GLU A 1 88 ? -43.580 -21.270 -2.382 1.00 77.37 ? 273 GLU A CA 1 ATOM 641 C C . GLU A 1 88 ? -44.204 -20.046 -1.723 1.00 77.42 ? 273 GLU A C 1 ATOM 642 O O . GLU A 1 88 ? -44.577 -19.089 -2.403 1.00 77.95 ? 273 GLU A O 1 ATOM 643 C CB . GLU A 1 88 ? -42.067 -21.073 -2.537 1.00 78.08 ? 273 GLU A CB 1 ATOM 644 C CG . GLU A 1 88 ? -41.663 -20.007 -3.561 1.00 78.64 ? 273 GLU A CG 1 ATOM 645 C CD . GLU A 1 88 ? -40.152 -19.856 -3.706 0.50 78.34 ? 273 GLU A CD 1 ATOM 646 O OE1 . GLU A 1 88 ? -39.403 -20.498 -2.937 0.50 78.58 ? 273 GLU A OE1 1 ATOM 647 O OE2 . GLU A 1 88 ? -39.715 -19.089 -4.591 0.50 78.31 ? 273 GLU A OE2 1 ATOM 648 N N . THR A 1 89 ? -44.315 -20.086 -0.397 1.00 77.43 ? 274 THR A N 1 ATOM 649 C CA . THR A 1 89 ? -44.854 -18.969 0.379 1.00 77.38 ? 274 THR A CA 1 ATOM 650 C C . THR A 1 89 ? -43.808 -18.452 1.358 1.00 77.24 ? 274 THR A C 1 ATOM 651 O O . THR A 1 89 ? -43.181 -19.231 2.074 1.00 76.56 ? 274 THR A O 1 ATOM 652 C CB . THR A 1 89 ? -46.116 -19.383 1.156 1.00 77.34 ? 274 THR A CB 1 ATOM 653 O OG1 . THR A 1 89 ? -47.211 -19.515 0.243 1.00 77.42 ? 274 THR A OG1 1 ATOM 654 C CG2 . THR A 1 89 ? -46.471 -18.343 2.215 1.00 77.33 ? 274 THR A CG2 1 ATOM 655 N N . LEU A 1 90 ? -43.634 -17.131 1.378 1.00 77.72 ? 275 LEU A N 1 ATOM 656 C CA . LEU A 1 90 ? -42.668 -16.468 2.251 1.00 77.55 ? 275 LEU A CA 1 ATOM 657 C C . LEU A 1 90 ? -43.397 -15.718 3.358 1.00 77.28 ? 275 LEU A C 1 ATOM 658 O O . LEU A 1 90 ? -44.491 -15.198 3.148 1.00 77.37 ? 275 LEU A O 1 ATOM 659 C CB . LEU A 1 90 ? -41.815 -15.491 1.435 1.00 77.89 ? 275 LEU A CB 1 ATOM 660 C CG . LEU A 1 90 ? -40.925 -14.506 2.200 1.00 77.77 ? 275 LEU A CG 1 ATOM 661 C CD1 . LEU A 1 90 ? -39.939 -15.252 3.078 1.00 77.59 ? 275 LEU A CD1 1 ATOM 662 C CD2 . LEU A 1 90 ? -40.199 -13.583 1.231 1.00 77.70 ? 275 LEU A CD2 1 ATOM 663 N N . GLN A 1 91 ? -42.784 -15.666 4.535 1.00 77.70 ? 276 GLN A N 1 ATOM 664 C CA . GLN A 1 91 ? -43.318 -14.891 5.651 1.00 77.66 ? 276 GLN A CA 1 ATOM 665 C C . GLN A 1 91 ? -42.193 -14.494 6.604 1.00 76.66 ? 276 GLN A C 1 ATOM 666 O O . GLN A 1 91 ? -41.364 -15.323 6.977 1.00 76.10 ? 276 GLN A O 1 ATOM 667 C CB . GLN A 1 91 ? -44.383 -15.697 6.398 1.00 78.09 ? 276 GLN A CB 1 ATOM 668 C CG . GLN A 1 91 ? -45.122 -14.906 7.471 1.00 78.48 ? 276 GLN A CG 1 ATOM 669 C CD . GLN A 1 91 ? -46.232 -15.705 8.127 1.00 79.14 ? 276 GLN A CD 1 ATOM 670 O OE1 . GLN A 1 91 ? -46.252 -15.875 9.349 1.00 79.87 ? 276 GLN A OE1 1 ATOM 671 N NE2 . GLN A 1 91 ? -47.162 -16.204 7.317 1.00 79.66 ? 276 GLN A NE2 1 ATOM 672 N N . THR A 1 92 ? -42.170 -13.222 6.991 1.00 76.51 ? 277 THR A N 1 ATOM 673 C CA . THR A 1 92 ? -41.143 -12.717 7.896 1.00 76.58 ? 277 THR A CA 1 ATOM 674 C C . THR A 1 92 ? -41.468 -13.091 9.338 1.00 76.07 ? 277 THR A C 1 ATOM 675 O O . THR A 1 92 ? -42.633 -13.113 9.738 1.00 76.49 ? 277 THR A O 1 ATOM 676 C CB . THR A 1 92 ? -40.996 -11.181 7.794 1.00 77.14 ? 277 THR A CB 1 ATOM 677 O OG1 . THR A 1 92 ? -42.250 -10.554 8.089 1.00 77.86 ? 277 THR A OG1 1 ATOM 678 C CG2 . THR A 1 92 ? -40.540 -10.773 6.398 1.00 76.70 ? 277 THR A CG2 1 ATOM 679 N N . VAL A 1 93 ? -40.427 -13.401 10.105 1.00 75.51 ? 278 VAL A N 1 ATOM 680 C CA . VAL A 1 93 ? -40.552 -13.657 11.536 1.00 75.33 ? 278 VAL A CA 1 ATOM 681 C C . VAL A 1 93 ? -39.379 -12.994 12.252 1.00 75.63 ? 278 VAL A C 1 ATOM 682 O O . VAL A 1 93 ? -38.222 -13.228 11.896 1.00 76.43 ? 278 VAL A O 1 ATOM 683 C CB . VAL A 1 93 ? -40.554 -15.166 11.843 1.00 74.17 ? 278 VAL A CB 1 ATOM 684 C CG1 . VAL A 1 93 ? -40.537 -15.406 13.344 1.00 73.34 ? 278 VAL A CG1 1 ATOM 685 C CG2 . VAL A 1 93 ? -41.762 -15.833 11.203 1.00 73.98 ? 278 VAL A CG2 1 ATOM 686 N N . THR A 1 94 ? -39.681 -12.163 13.247 1.00 74.99 ? 279 THR A N 1 ATOM 687 C CA . THR A 1 94 ? -38.652 -11.436 13.989 1.00 74.98 ? 279 THR A CA 1 ATOM 688 C C . THR A 1 94 ? -38.307 -12.162 15.286 1.00 74.71 ? 279 THR A C 1 ATOM 689 O O . THR A 1 94 ? -39.155 -12.303 16.167 1.00 74.78 ? 279 THR A O 1 ATOM 690 C CB . THR A 1 94 ? -39.109 -10.003 14.322 1.00 74.64 ? 279 THR A CB 1 ATOM 691 O OG1 . THR A 1 94 ? -39.512 -9.336 13.120 1.00 74.65 ? 279 THR A OG1 1 ATOM 692 C CG2 . THR A 1 94 ? -37.983 -9.219 14.978 1.00 74.68 ? 279 THR A CG2 1 ATOM 693 N N . ILE A 1 95 ? -37.064 -12.625 15.396 1.00 74.62 ? 280 ILE A N 1 ATOM 694 C CA . ILE A 1 95 ? -36.579 -13.244 16.627 1.00 74.95 ? 280 ILE A CA 1 ATOM 695 C C . ILE A 1 95 ? -35.972 -12.157 17.512 1.00 75.49 ? 280 ILE A C 1 ATOM 696 O O . ILE A 1 95 ? -34.979 -11.529 17.138 1.00 76.06 ? 280 ILE A O 1 ATOM 697 C CB . ILE A 1 95 ? -35.532 -14.349 16.357 1.00 74.76 ? 280 ILE A CB 1 ATOM 698 C CG1 . ILE A 1 95 ? -36.165 -15.524 15.604 1.00 74.91 ? 280 ILE A CG1 1 ATOM 699 C CG2 . ILE A 1 95 ? -34.940 -14.851 17.665 1.00 74.42 ? 280 ILE A CG2 1 ATOM 700 C CD1 . ILE A 1 95 ? -36.354 -15.283 14.126 1.00 74.77 ? 280 ILE A CD1 1 ATOM 701 N N . TYR A 1 96 ? -36.575 -11.941 18.680 1.00 75.21 ? 281 TYR A N 1 ATOM 702 C CA . TYR A 1 96 ? -36.190 -10.840 19.565 1.00 74.73 ? 281 TYR A CA 1 ATOM 703 C C . TYR A 1 96 ? -35.661 -11.363 20.897 1.00 74.37 ? 281 TYR A C 1 ATOM 704 O O . TYR A 1 96 ? -36.130 -12.383 21.405 1.00 74.36 ? 281 TYR A O 1 ATOM 705 C CB . TYR A 1 96 ? -37.384 -9.905 19.806 1.00 74.85 ? 281 TYR A CB 1 ATOM 706 C CG . TYR A 1 96 ? -38.534 -10.542 20.560 1.00 74.91 ? 281 TYR A CG 1 ATOM 707 C CD1 . TYR A 1 96 ? -39.518 -11.260 19.889 1.00 75.01 ? 281 TYR A CD1 1 ATOM 708 C CD2 . TYR A 1 96 ? -38.636 -10.427 21.944 1.00 74.93 ? 281 TYR A CD2 1 ATOM 709 C CE1 . TYR A 1 96 ? -40.571 -11.849 20.576 1.00 75.01 ? 281 TYR A CE1 1 ATOM 710 C CE2 . TYR A 1 96 ? -39.686 -11.014 22.640 1.00 74.79 ? 281 TYR A CE2 1 ATOM 711 C CZ . TYR A 1 96 ? -40.649 -11.722 21.949 1.00 74.84 ? 281 TYR A CZ 1 ATOM 712 O OH . TYR A 1 96 ? -41.694 -12.306 22.628 1.00 74.96 ? 281 TYR A OH 1 ATOM 713 N N . SER A 1 97 ? -34.675 -10.661 21.450 1.00 74.02 ? 282 SER A N 1 ATOM 714 C CA . SER A 1 97 ? -34.175 -10.948 22.787 1.00 74.36 ? 282 SER A CA 1 ATOM 715 C C . SER A 1 97 ? -34.667 -9.859 23.732 1.00 74.53 ? 282 SER A C 1 ATOM 716 O O . SER A 1 97 ? -34.334 -8.684 23.564 1.00 74.96 ? 282 SER A O 1 ATOM 717 C CB . SER A 1 97 ? -32.648 -11.005 22.794 1.00 74.25 ? 282 SER A CB 1 ATOM 718 O OG . SER A 1 97 ? -32.165 -11.462 24.046 1.00 74.18 ? 282 SER A OG 1 ATOM 719 N N . PHE A 1 98 ? -35.471 -10.257 24.715 1.00 74.43 ? 283 PHE A N 1 ATOM 720 C CA . PHE A 1 98 ? -36.064 -9.321 25.661 1.00 74.78 ? 283 PHE A CA 1 ATOM 721 C C . PHE A 1 98 ? -36.018 -9.911 27.069 1.00 74.86 ? 283 PHE A C 1 ATOM 722 O O . PHE A 1 98 ? -36.968 -10.561 27.504 1.00 74.60 ? 283 PHE A O 1 ATOM 723 C CB . PHE A 1 98 ? -37.504 -8.991 25.241 1.00 74.47 ? 283 PHE A CB 1 ATOM 724 C CG . PHE A 1 98 ? -38.223 -8.048 26.177 1.00 74.17 ? 283 PHE A CG 1 ATOM 725 C CD1 . PHE A 1 98 ? -39.546 -8.280 26.525 1.00 74.23 ? 283 PHE A CD1 1 ATOM 726 C CD2 . PHE A 1 98 ? -37.581 -6.931 26.704 1.00 74.38 ? 283 PHE A CD2 1 ATOM 727 C CE1 . PHE A 1 98 ? -40.219 -7.417 27.381 1.00 74.55 ? 283 PHE A CE1 1 ATOM 728 C CE2 . PHE A 1 98 ? -38.247 -6.066 27.564 1.00 74.47 ? 283 PHE A CE2 1 ATOM 729 C CZ . PHE A 1 98 ? -39.567 -6.309 27.902 1.00 74.56 ? 283 PHE A CZ 1 ATOM 730 N N . PRO A 1 99 ? -34.891 -9.704 27.778 1.00 75.36 ? 284 PRO A N 1 ATOM 731 C CA . PRO A 1 99 ? -34.755 -10.146 29.167 1.00 75.73 ? 284 PRO A CA 1 ATOM 732 C C . PRO A 1 99 ? -35.797 -9.513 30.083 1.00 76.21 ? 284 PRO A C 1 ATOM 733 O O . PRO A 1 99 ? -36.320 -8.441 29.776 1.00 76.79 ? 284 PRO A O 1 ATOM 734 C CB . PRO A 1 99 ? -33.350 -9.667 29.556 1.00 75.72 ? 284 PRO A CB 1 ATOM 735 C CG . PRO A 1 99 ? -32.631 -9.482 28.272 1.00 75.59 ? 284 PRO A CG 1 ATOM 736 C CD . PRO A 1 99 ? -33.662 -9.053 27.288 1.00 75.46 ? 284 PRO A CD 1 ATOM 737 N N . ALA A 1 100 ? -36.094 -10.177 31.196 1.00 76.34 ? 285 ALA A N 1 ATOM 738 C CA . ALA A 1 100 ? -37.020 -9.633 32.183 1.00 76.47 ? 285 ALA A CA 1 ATOM 739 C C . ALA A 1 100 ? -36.394 -8.402 32.838 1.00 76.92 ? 285 ALA A C 1 ATOM 740 O O . ALA A 1 100 ? -35.173 -8.344 32.995 1.00 77.57 ? 285 ALA A O 1 ATOM 741 C CB . ALA A 1 100 ? -37.354 -10.678 33.231 1.00 76.70 ? 285 ALA A CB 1 ATOM 742 N N . PRO A 1 101 ? -37.221 -7.412 33.219 1.00 76.79 ? 286 PRO A N 1 ATOM 743 C CA . PRO A 1 101 ? -36.682 -6.212 33.868 1.00 76.93 ? 286 PRO A CA 1 ATOM 744 C C . PRO A 1 101 ? -35.963 -6.537 35.174 1.00 77.77 ? 286 PRO A C 1 ATOM 745 O O . PRO A 1 101 ? -36.410 -7.408 35.924 1.00 78.32 ? 286 PRO A O 1 ATOM 746 C CB . PRO A 1 101 ? -37.930 -5.368 34.151 1.00 76.62 ? 286 PRO A CB 1 ATOM 747 C CG . PRO A 1 101 ? -38.981 -5.905 33.260 1.00 76.85 ? 286 PRO A CG 1 ATOM 748 C CD . PRO A 1 101 ? -38.686 -7.349 33.078 1.00 76.77 ? 286 PRO A CD 1 ATOM 749 N N . ASN A 1 102 ? -34.858 -5.843 35.435 1.00 77.95 ? 287 ASN A N 1 ATOM 750 C CA . ASN A 1 102 ? -34.079 -6.058 36.653 1.00 77.97 ? 287 ASN A CA 1 ATOM 751 C C . ASN A 1 102 ? -34.431 -5.047 37.735 1.00 77.58 ? 287 ASN A C 1 ATOM 752 O O . ASN A 1 102 ? -33.850 -3.966 37.792 1.00 77.49 ? 287 ASN A O 1 ATOM 753 C CB . ASN A 1 102 ? -32.578 -5.983 36.351 1.00 78.82 ? 287 ASN A CB 1 ATOM 754 C CG . ASN A 1 102 ? -32.076 -7.191 35.584 1.00 79.73 ? 287 ASN A CG 1 ATOM 755 O OD1 . ASN A 1 102 ? -32.259 -8.331 36.012 1.00 80.21 ? 287 ASN A OD1 1 ATOM 756 N ND2 . ASN A 1 102 ? -31.427 -6.946 34.448 1.00 79.81 ? 287 ASN A ND2 1 ATOM 757 N N . VAL A 1 103 ? -35.387 -5.406 38.589 1.00 78.08 ? 288 VAL A N 1 ATOM 758 C CA . VAL A 1 103 ? -35.680 -4.621 39.788 1.00 78.59 ? 288 VAL A CA 1 ATOM 759 C C . VAL A 1 103 ? -34.545 -4.842 40.780 1.00 79.10 ? 288 VAL A C 1 ATOM 760 O O . VAL A 1 103 ? -34.306 -5.968 41.209 1.00 79.23 ? 288 VAL A O 1 ATOM 761 C CB . VAL A 1 103 ? -37.012 -5.035 40.446 1.00 77.79 ? 288 VAL A CB 1 ATOM 762 C CG1 . VAL A 1 103 ? -37.300 -4.162 41.658 1.00 77.03 ? 288 VAL A CG1 1 ATOM 763 C CG2 . VAL A 1 103 ? -38.152 -4.948 39.446 1.00 78.20 ? 288 VAL A CG2 1 ATOM 764 N N . ILE A 1 104 ? -33.842 -3.768 41.129 1.00 79.76 ? 289 ILE A N 1 ATOM 765 C CA . ILE A 1 104 ? -32.630 -3.870 41.940 1.00 80.44 ? 289 ILE A CA 1 ATOM 766 C C . ILE A 1 104 ? -32.720 -2.964 43.171 1.00 80.97 ? 289 ILE A C 1 ATOM 767 O O . ILE A 1 104 ? -32.996 -1.767 43.057 1.00 80.93 ? 289 ILE A O 1 ATOM 768 C CB . ILE A 1 104 ? -31.363 -3.539 41.095 1.00 80.84 ? 289 ILE A CB 1 ATOM 769 C CG1 . ILE A 1 104 ? -30.087 -3.687 41.931 1.00 81.11 ? 289 ILE A CG1 1 ATOM 770 C CG2 . ILE A 1 104 ? -31.453 -2.142 40.493 1.00 80.69 ? 289 ILE A CG2 1 ATOM 771 C CD1 . ILE A 1 104 ? -28.809 -3.617 41.105 1.00 80.86 ? 289 ILE A CD1 1 ATOM 772 N N . LEU A 1 105 ? -32.500 -3.556 44.344 1.00 81.32 ? 290 LEU A N 1 ATOM 773 C CA . LEU A 1 105 ? -32.531 -2.830 45.612 1.00 81.68 ? 290 LEU A CA 1 ATOM 774 C C . LEU A 1 105 ? -31.107 -2.595 46.107 1.00 82.37 ? 290 LEU A C 1 ATOM 775 O O . LEU A 1 105 ? -30.244 -3.465 45.961 1.00 82.46 ? 290 LEU A O 1 ATOM 776 C CB . LEU A 1 105 ? -33.317 -3.623 46.657 1.00 81.74 ? 290 LEU A CB 1 ATOM 777 C CG . LEU A 1 105 ? -34.720 -4.080 46.243 1.00 82.09 ? 290 LEU A CG 1 ATOM 778 C CD1 . LEU A 1 105 ? -35.311 -5.014 47.290 1.00 81.92 ? 290 LEU A CD1 1 ATOM 779 C CD2 . LEU A 1 105 ? -35.631 -2.885 46.011 1.00 82.29 ? 290 LEU A CD2 1 ATOM 780 N N . THR A 1 106 ? -30.864 -1.419 46.686 1.00 82.76 ? 291 THR A N 1 ATOM 781 C CA . THR A 1 106 ? -29.547 -1.079 47.236 1.00 82.86 ? 291 THR A CA 1 ATOM 782 C C . THR A 1 106 ? -29.117 -2.114 48.268 1.00 83.08 ? 291 THR A C 1 ATOM 783 O O . THR A 1 106 ? -27.993 -2.620 48.223 1.00 82.86 ? 291 THR A O 1 ATOM 784 C CB . THR A 1 106 ? -29.545 0.317 47.904 1.00 83.18 ? 291 THR A CB 1 ATOM 785 O OG1 . THR A 1 106 ? -30.752 0.494 48.660 1.00 83.05 ? 291 THR A OG1 1 ATOM 786 C CG2 . THR A 1 106 ? -29.434 1.415 46.855 1.00 83.26 ? 291 THR A CG2 1 ATOM 787 N N . LYS A 1 107 ? -30.020 -2.411 49.198 1.00 83.11 ? 292 LYS A N 1 ATOM 788 C CA . LYS A 1 107 ? -29.824 -3.483 50.167 1.00 83.09 ? 292 LYS A CA 1 ATOM 789 C C . LYS A 1 107 ? -31.134 -4.257 50.308 1.00 83.09 ? 292 LYS A C 1 ATOM 790 O O . LYS A 1 107 ? -32.203 -3.648 50.371 1.00 82.75 ? 292 LYS A O 1 ATOM 791 C CB . LYS A 1 107 ? -29.396 -2.914 51.523 1.00 83.19 ? 292 LYS A CB 1 ATOM 792 C CG . LYS A 1 107 ? -28.260 -1.899 51.447 1.00 83.15 ? 292 LYS A CG 1 ATOM 793 C CD . LYS A 1 107 ? -27.723 -1.543 52.825 1.00 83.17 ? 292 LYS A CD 1 ATOM 794 C CE . LYS A 1 107 ? -26.710 -2.566 53.314 1.00 83.37 ? 292 LYS A CE 1 ATOM 795 N NZ . LYS A 1 107 ? -26.264 -2.288 54.708 1.00 83.36 ? 292 LYS A NZ 1 ATOM 796 N N . PRO A 1 108 ? -31.058 -5.602 50.353 1.00 83.63 ? 293 PRO A N 1 ATOM 797 C CA . PRO A 1 108 ? -32.272 -6.422 50.428 1.00 83.35 ? 293 PRO A CA 1 ATOM 798 C C . PRO A 1 108 ? -32.994 -6.306 51.774 1.00 83.07 ? 293 PRO A C 1 ATOM 799 O O . PRO A 1 108 ? -34.224 -6.264 51.805 1.00 83.20 ? 293 PRO A O 1 ATOM 800 C CB . PRO A 1 108 ? -31.750 -7.847 50.207 1.00 83.56 ? 293 PRO A CB 1 ATOM 801 C CG . PRO A 1 108 ? -30.336 -7.810 50.646 1.00 83.72 ? 293 PRO A CG 1 ATOM 802 C CD . PRO A 1 108 ? -29.835 -6.427 50.345 1.00 83.81 ? 293 PRO A CD 1 ATOM 803 N N . GLU A 1 109 ? -32.232 -6.259 52.866 1.00 83.03 ? 294 GLU A N 1 ATOM 804 C CA . GLU A 1 109 ? -32.788 -6.054 54.204 1.00 83.04 ? 294 GLU A CA 1 ATOM 805 C C . GLU A 1 109 ? -32.191 -4.790 54.822 1.00 82.49 ? 294 GLU A C 1 ATOM 806 O O . GLU A 1 109 ? -30.971 -4.667 54.936 1.00 82.43 ? 294 GLU A O 1 ATOM 807 C CB . GLU A 1 109 ? -32.506 -7.266 55.098 1.00 83.24 ? 294 GLU A CB 1 ATOM 808 C CG . GLU A 1 109 ? -33.007 -7.118 56.532 1.00 83.58 ? 294 GLU A CG 1 ATOM 809 C CD . GLU A 1 109 ? -32.989 -8.428 57.303 1.00 84.32 ? 294 GLU A CD 1 ATOM 810 O OE1 . GLU A 1 109 ? -33.889 -9.263 57.076 1.00 85.02 ? 294 GLU A OE1 1 ATOM 811 O OE2 . GLU A 1 109 ? -32.081 -8.615 58.145 1.00 84.86 ? 294 GLU A OE2 1 ATOM 812 N N . VAL A 1 110 ? -33.057 -3.861 55.223 1.00 81.99 ? 295 VAL A N 1 ATOM 813 C CA . VAL A 1 110 ? -32.626 -2.567 55.754 1.00 82.01 ? 295 VAL A CA 1 ATOM 814 C C . VAL A 1 110 ? -33.268 -2.298 57.116 1.00 81.75 ? 295 VAL A C 1 ATOM 815 O O . VAL A 1 110 ? -34.260 -2.931 57.479 1.00 81.41 ? 295 VAL A O 1 ATOM 816 C CB . VAL A 1 110 ? -32.997 -1.422 54.785 1.00 82.13 ? 295 VAL A CB 1 ATOM 817 C CG1 . VAL A 1 110 ? -32.113 -0.213 55.025 1.00 82.24 ? 295 VAL A CG1 1 ATOM 818 C CG2 . VAL A 1 110 ? -32.866 -1.881 53.342 1.00 82.47 ? 295 VAL A CG2 1 ATOM 819 N N . SER A 1 111 ? -32.688 -1.367 57.872 1.00 81.71 ? 296 SER A N 1 ATOM 820 C CA . SER A 1 111 ? -33.262 -0.936 59.148 1.00 81.48 ? 296 SER A CA 1 ATOM 821 C C . SER A 1 111 ? -34.290 0.172 58.935 1.00 80.87 ? 296 SER A C 1 ATOM 822 O O . SER A 1 111 ? -34.305 0.828 57.894 1.00 80.93 ? 296 SER A O 1 ATOM 823 C CB . SER A 1 111 ? -32.164 -0.445 60.090 1.00 82.69 ? 296 SER A CB 1 ATOM 824 O OG . SER A 1 111 ? -31.221 -1.469 60.349 1.00 83.77 ? 296 SER A OG 1 ATOM 825 N N . GLU A 1 112 ? -35.141 0.376 59.936 1.00 80.63 ? 297 GLU A N 1 ATOM 826 C CA . GLU A 1 112 ? -36.197 1.389 59.882 1.00 80.48 ? 297 GLU A CA 1 ATOM 827 C C . GLU A 1 112 ? -35.604 2.792 59.742 1.00 79.98 ? 297 GLU A C 1 ATOM 828 O O . GLU A 1 112 ? -34.551 3.089 60.308 1.00 79.79 ? 297 GLU A O 1 ATOM 829 C CB . GLU A 1 112 ? -37.054 1.309 61.152 1.00 80.53 ? 297 GLU A CB 1 ATOM 830 C CG . GLU A 1 112 ? -38.307 2.185 61.153 1.00 80.70 ? 297 GLU A CG 1 ATOM 831 C CD . GLU A 1 112 ? -39.049 2.157 62.489 1.00 81.09 ? 297 GLU A CD 1 ATOM 832 O OE1 . GLU A 1 112 ? -38.553 1.522 63.448 1.00 80.87 ? 297 GLU A OE1 1 ATOM 833 O OE2 . GLU A 1 112 ? -40.132 2.776 62.581 1.00 81.70 ? 297 GLU A OE2 1 ATOM 834 N N . GLY A 1 113 ? -36.282 3.645 58.977 1.00 79.89 ? 298 GLY A N 1 ATOM 835 C CA . GLY A 1 113 ? -35.865 5.039 58.802 1.00 79.85 ? 298 GLY A CA 1 ATOM 836 C C . GLY A 1 113 ? -34.659 5.243 57.896 1.00 79.43 ? 298 GLY A C 1 ATOM 837 O O . GLY A 1 113 ? -34.044 6.309 57.913 1.00 79.06 ? 298 GLY A O 1 ATOM 838 N N . THR A 1 114 ? -34.330 4.231 57.095 1.00 79.57 ? 299 THR A N 1 ATOM 839 C CA . THR A 1 114 ? -33.179 4.288 56.195 1.00 79.65 ? 299 THR A CA 1 ATOM 840 C C . THR A 1 114 ? -33.614 4.687 54.787 1.00 79.59 ? 299 THR A C 1 ATOM 841 O O . THR A 1 114 ? -34.706 4.329 54.342 1.00 79.58 ? 299 THR A O 1 ATOM 842 C CB . THR A 1 114 ? -32.466 2.924 56.122 1.00 79.59 ? 299 THR A CB 1 ATOM 843 O OG1 . THR A 1 114 ? -32.164 2.466 57.445 1.00 79.49 ? 299 THR A OG1 1 ATOM 844 C CG2 . THR A 1 114 ? -31.177 3.026 55.315 1.00 79.71 ? 299 THR A CG2 1 ATOM 845 N N . GLU A 1 115 ? -32.750 5.422 54.090 1.00 79.63 ? 300 GLU A N 1 ATOM 846 C CA . GLU A 1 115 ? -33.036 5.878 52.731 1.00 79.84 ? 300 GLU A CA 1 ATOM 847 C C . GLU A 1 115 ? -32.810 4.752 51.725 1.00 79.64 ? 300 GLU A C 1 ATOM 848 O O . GLU A 1 115 ? -31.679 4.504 51.303 1.00 79.62 ? 300 GLU A O 1 ATOM 849 C CB . GLU A 1 115 ? -32.155 7.082 52.370 1.00 80.84 ? 300 GLU A CB 1 ATOM 850 C CG . GLU A 1 115 ? -32.322 8.295 53.286 1.00 81.79 ? 300 GLU A CG 1 ATOM 851 C CD . GLU A 1 115 ? -33.712 8.914 53.224 1.00 82.59 ? 300 GLU A CD 1 ATOM 852 O OE1 . GLU A 1 115 ? -34.437 8.685 52.231 1.00 82.70 ? 300 GLU A OE1 1 ATOM 853 O OE2 . GLU A 1 115 ? -34.075 9.640 54.174 1.00 83.03 ? 300 GLU A OE2 1 ATOM 854 N N . VAL A 1 116 ? -33.892 4.071 51.353 1.00 79.59 ? 301 VAL A N 1 ATOM 855 C CA . VAL A 1 116 ? -33.843 2.989 50.369 1.00 79.58 ? 301 VAL A CA 1 ATOM 856 C C . VAL A 1 116 ? -34.294 3.506 49.006 1.00 79.12 ? 301 VAL A C 1 ATOM 857 O O . VAL A 1 116 ? -35.294 4.218 48.910 1.00 78.95 ? 301 VAL A O 1 ATOM 858 C CB . VAL A 1 116 ? -34.758 1.814 50.778 1.00 80.15 ? 301 VAL A CB 1 ATOM 859 C CG1 . VAL A 1 116 ? -34.674 0.686 49.757 1.00 80.00 ? 301 VAL A CG1 1 ATOM 860 C CG2 . VAL A 1 116 ? -34.391 1.309 52.167 1.00 80.56 ? 301 VAL A CG2 1 ATOM 861 N N . THR A 1 117 ? -33.555 3.141 47.959 1.00 79.14 ? 302 THR A N 1 ATOM 862 C CA . THR A 1 117 ? -33.895 3.534 46.589 1.00 79.40 ? 302 THR A CA 1 ATOM 863 C C . THR A 1 117 ? -34.067 2.299 45.704 1.00 79.17 ? 302 THR A C 1 ATOM 864 O O . THR A 1 117 ? -33.178 1.450 45.626 1.00 78.90 ? 302 THR A O 1 ATOM 865 C CB . THR A 1 117 ? -32.831 4.483 45.976 1.00 79.56 ? 302 THR A CB 1 ATOM 866 O OG1 . THR A 1 117 ? -33.156 4.753 44.606 1.00 79.33 ? 302 THR A OG1 1 ATOM 867 C CG2 . THR A 1 117 ? -31.434 3.878 46.054 1.00 79.75 ? 302 THR A CG2 1 ATOM 868 N N . VAL A 1 118 ? -35.222 2.211 45.045 1.00 79.36 ? 303 VAL A N 1 ATOM 869 C CA . VAL A 1 118 ? -35.567 1.066 44.206 1.00 79.63 ? 303 VAL A CA 1 ATOM 870 C C . VAL A 1 118 ? -35.480 1.445 42.731 1.00 79.43 ? 303 VAL A C 1 ATOM 871 O O . VAL A 1 118 ? -36.167 2.363 42.279 1.00 79.08 ? 303 VAL A O 1 ATOM 872 C CB . VAL A 1 118 ? -36.995 0.567 44.509 1.00 79.56 ? 303 VAL A CB 1 ATOM 873 C CG1 . VAL A 1 118 ? -37.323 -0.658 43.666 1.00 79.79 ? 303 VAL A CG1 1 ATOM 874 C CG2 . VAL A 1 118 ? -37.147 0.253 45.991 1.00 79.21 ? 303 VAL A CG2 1 ATOM 875 N N . LYS A 1 119 ? -34.636 0.729 41.989 1.00 80.07 ? 304 LYS A N 1 ATOM 876 C CA . LYS A 1 119 ? -34.435 0.981 40.561 1.00 80.82 ? 304 LYS A CA 1 ATOM 877 C C . LYS A 1 119 ? -34.906 -0.212 39.730 1.00 81.97 ? 304 LYS A C 1 ATOM 878 O O . LYS A 1 119 ? -34.923 -1.345 40.214 1.00 81.81 ? 304 LYS A O 1 ATOM 879 C CB . LYS A 1 119 ? -32.954 1.237 40.269 1.00 80.58 ? 304 LYS A CB 1 ATOM 880 C CG . LYS A 1 119 ? -32.311 2.312 41.130 1.00 80.55 ? 304 LYS A CG 1 ATOM 881 C CD . LYS A 1 119 ? -30.874 2.574 40.700 1.00 80.60 ? 304 LYS A CD 1 ATOM 882 C CE . LYS A 1 119 ? -30.219 3.647 41.553 1.00 80.55 ? 304 LYS A CE 1 ATOM 883 N NZ . LYS A 1 119 ? -28.809 3.902 41.148 1.00 80.51 ? 304 LYS A NZ 1 ATOM 884 N N . CYS A 1 120 ? -35.287 0.053 38.481 1.00 83.28 ? 305 CYS A N 1 ATOM 885 C CA . CYS A 1 120 ? -35.615 -1.006 37.526 1.00 82.07 ? 305 CYS A CA 1 ATOM 886 C C . CYS A 1 120 ? -35.086 -0.678 36.134 1.00 81.39 ? 305 CYS A C 1 ATOM 887 O O . CYS A 1 120 ? -35.598 0.224 35.479 1.00 81.35 ? 305 CYS A O 1 ATOM 888 C CB . CYS A 1 120 ? -37.126 -1.224 37.442 1.00 83.87 ? 305 CYS A CB 1 ATOM 889 S SG . CYS A 1 120 ? -37.570 -2.413 36.142 1.00 86.12 ? 305 CYS A SG 1 ATOM 890 N N . GLU A 1 121 ? -34.075 -1.421 35.686 1.00 81.11 ? 306 GLU A N 1 ATOM 891 C CA . GLU A 1 121 ? -33.531 -1.265 34.334 1.00 81.04 ? 306 GLU A CA 1 ATOM 892 C C . GLU A 1 121 ? -34.006 -2.403 33.427 1.00 80.38 ? 306 GLU A C 1 ATOM 893 O O . GLU A 1 121 ? -34.266 -3.511 33.896 1.00 80.23 ? 306 GLU A O 1 ATOM 894 C CB . GLU A 1 121 ? -31.999 -1.218 34.373 1.00 81.10 ? 306 GLU A CB 1 ATOM 895 C CG . GLU A 1 121 ? -31.353 -0.818 33.042 1.00 81.38 ? 306 GLU A CG 1 ATOM 896 C CD . GLU A 1 121 ? -29.867 -0.499 33.161 1.00 81.78 ? 306 GLU A CD 1 ATOM 897 O OE1 . GLU A 1 121 ? -29.289 -0.698 34.252 1.00 82.67 ? 306 GLU A OE1 1 ATOM 898 O OE2 . GLU A 1 121 ? -29.276 -0.048 32.157 1.00 81.50 ? 306 GLU A OE2 1 ATOM 899 N N . ALA A 1 122 ? -34.117 -2.116 32.131 1.00 80.09 ? 307 ALA A N 1 ATOM 900 C CA . ALA A 1 122 ? -34.599 -3.093 31.152 1.00 79.91 ? 307 ALA A CA 1 ATOM 901 C C . ALA A 1 122 ? -33.902 -2.913 29.800 1.00 79.99 ? 307 ALA A C 1 ATOM 902 O O . ALA A 1 122 ? -32.851 -2.273 29.716 1.00 80.13 ? 307 ALA A O 1 ATOM 903 C CB . ALA A 1 122 ? -36.108 -2.967 30.997 1.00 79.42 ? 307 ALA A CB 1 ATOM 904 N N . HIS A 1 123 ? -34.485 -3.495 28.750 1.00 80.10 ? 308 HIS A N 1 ATOM 905 C CA . HIS A 1 123 ? -33.961 -3.373 27.387 1.00 79.55 ? 308 HIS A CA 1 ATOM 906 C C . HIS A 1 123 ? -33.971 -1.902 26.949 1.00 79.18 ? 308 HIS A C 1 ATOM 907 O O . HIS A 1 123 ? -34.968 -1.209 27.156 1.00 79.24 ? 308 HIS A O 1 ATOM 908 C CB . HIS A 1 123 ? -34.803 -4.221 26.422 1.00 80.10 ? 308 HIS A CB 1 ATOM 909 C CG . HIS A 1 123 ? -34.236 -4.320 25.039 1.00 80.49 ? 308 HIS A CG 1 ATOM 910 N ND1 . HIS A 1 123 ? -33.258 -5.229 24.697 1.00 80.87 ? 308 HIS A ND1 1 ATOM 911 C CD2 . HIS A 1 123 ? -34.521 -3.632 23.907 1.00 80.58 ? 308 HIS A CD2 1 ATOM 912 C CE1 . HIS A 1 123 ? -32.957 -5.090 23.418 1.00 80.61 ? 308 HIS A CE1 1 ATOM 913 N NE2 . HIS A 1 123 ? -33.709 -4.127 22.915 1.00 80.46 ? 308 HIS A NE2 1 ATOM 914 N N . PRO A 1 124 ? -32.856 -1.418 26.361 1.00 78.75 ? 309 PRO A N 1 ATOM 915 C CA . PRO A 1 124 ? -32.716 -0.017 25.938 1.00 78.56 ? 309 PRO A CA 1 ATOM 916 C C . PRO A 1 124 ? -33.930 0.574 25.206 1.00 78.06 ? 309 PRO A C 1 ATOM 917 O O . PRO A 1 124 ? -34.369 1.675 25.539 1.00 78.02 ? 309 PRO A O 1 ATOM 918 C CB . PRO A 1 124 ? -31.503 -0.058 25.005 1.00 78.53 ? 309 PRO A CB 1 ATOM 919 C CG . PRO A 1 124 ? -30.678 -1.168 25.522 1.00 78.47 ? 309 PRO A CG 1 ATOM 920 C CD . PRO A 1 124 ? -31.629 -2.191 26.083 1.00 78.57 ? 309 PRO A CD 1 ATOM 921 N N . ARG A 1 125 ? -34.454 -0.148 24.218 1.00 77.71 ? 310 ARG A N 1 ATOM 922 C CA . ARG A 1 125 ? -35.610 0.325 23.448 1.00 77.79 ? 310 ARG A CA 1 ATOM 923 C C . ARG A 1 125 ? -36.940 0.138 24.183 1.00 77.08 ? 310 ARG A C 1 ATOM 924 O O . ARG A 1 125 ? -37.946 0.744 23.809 1.00 76.54 ? 310 ARG A O 1 ATOM 925 C CB . ARG A 1 125 ? -35.677 -0.372 22.086 1.00 78.33 ? 310 ARG A CB 1 ATOM 926 C CG . ARG A 1 125 ? -34.487 -0.081 21.171 1.00 78.62 ? 310 ARG A CG 1 ATOM 927 C CD . ARG A 1 125 ? -34.820 -0.344 19.701 1.00 78.63 ? 310 ARG A CD 1 ATOM 928 N NE . ARG A 1 125 ? -35.714 -1.492 19.531 1.00 78.98 ? 310 ARG A NE 1 ATOM 929 C CZ . ARG A 1 125 ? -35.347 -2.770 19.626 1.00 79.10 ? 310 ARG A CZ 1 ATOM 930 N NH1 . ARG A 1 125 ? -34.085 -3.103 19.890 1.00 79.20 ? 310 ARG A NH1 1 ATOM 931 N NH2 . ARG A 1 125 ? -36.254 -3.728 19.458 1.00 78.95 ? 310 ARG A NH2 1 ATOM 932 N N . ALA A 1 126 ? -36.945 -0.703 25.218 1.00 77.12 ? 311 ALA A N 1 ATOM 933 C CA . ALA A 1 126 ? -38.151 -0.952 26.014 1.00 76.54 ? 311 ALA A CA 1 ATOM 934 C C . ALA A 1 126 ? -38.473 0.229 26.928 1.00 75.97 ? 311 ALA A C 1 ATOM 935 O O . ALA A 1 126 ? -37.616 1.075 27.185 1.00 76.03 ? 311 ALA A O 1 ATOM 936 C CB . ALA A 1 126 ? -37.987 -2.219 26.834 1.00 76.06 ? 311 ALA A CB 1 ATOM 937 N N . LYS A 1 127 ? -39.712 0.274 27.414 1.00 75.65 ? 312 LYS A N 1 ATOM 938 C CA . LYS A 1 127 ? -40.172 1.346 28.299 1.00 75.84 ? 312 LYS A CA 1 ATOM 939 C C . LYS A 1 127 ? -40.758 0.751 29.579 1.00 75.95 ? 312 LYS A C 1 ATOM 940 O O . LYS A 1 127 ? -41.651 -0.094 29.521 1.00 76.06 ? 312 LYS A O 1 ATOM 941 C CB . LYS A 1 127 ? -41.219 2.206 27.590 1.00 75.88 ? 312 LYS A CB 1 ATOM 942 C CG . LYS A 1 127 ? -40.755 2.777 26.256 1.00 75.92 ? 312 LYS A CG 1 ATOM 943 C CD . LYS A 1 127 ? -41.856 3.572 25.574 1.00 75.81 ? 312 LYS A CD 1 ATOM 944 C CE . LYS A 1 127 ? -41.530 3.822 24.111 1.00 75.93 ? 312 LYS A CE 1 ATOM 945 N NZ . LYS A 1 127 ? -42.619 4.551 23.406 1.00 76.10 ? 312 LYS A NZ 1 ATOM 946 N N . VAL A 1 128 ? -40.262 1.208 30.729 1.00 76.19 ? 313 VAL A N 1 ATOM 947 C CA . VAL A 1 128 ? -40.572 0.576 32.020 1.00 75.68 ? 313 VAL A CA 1 ATOM 948 C C . VAL A 1 128 ? -41.440 1.440 32.938 1.00 75.25 ? 313 VAL A C 1 ATOM 949 O O . VAL A 1 128 ? -41.514 2.659 32.783 1.00 74.88 ? 313 VAL A O 1 ATOM 950 C CB . VAL A 1 128 ? -39.285 0.214 32.787 1.00 74.80 ? 313 VAL A CB 1 ATOM 951 C CG1 . VAL A 1 128 ? -38.396 -0.681 31.938 1.00 74.52 ? 313 VAL A CG1 1 ATOM 952 C CG2 . VAL A 1 128 ? -38.544 1.471 33.209 1.00 74.46 ? 313 VAL A CG2 1 ATOM 953 N N . THR A 1 129 ? -42.082 0.780 33.901 1.00 75.79 ? 314 THR A N 1 ATOM 954 C CA . THR A 1 129 ? -42.923 1.438 34.902 1.00 76.14 ? 314 THR A CA 1 ATOM 955 C C . THR A 1 129 ? -42.772 0.719 36.243 1.00 76.03 ? 314 THR A C 1 ATOM 956 O O . THR A 1 129 ? -42.936 -0.499 36.316 1.00 75.82 ? 314 THR A O 1 ATOM 957 C CB . THR A 1 129 ? -44.407 1.409 34.489 1.00 76.14 ? 314 THR A CB 1 ATOM 958 O OG1 . THR A 1 129 ? -44.568 2.056 33.221 1.00 76.27 ? 314 THR A OG1 1 ATOM 959 C CG2 . THR A 1 129 ? -45.273 2.110 35.526 1.00 75.97 ? 314 THR A CG2 1 ATOM 960 N N . LEU A 1 130 ? -42.468 1.479 37.294 1.00 76.44 ? 315 LEU A N 1 ATOM 961 C CA . LEU A 1 130 ? -42.213 0.922 38.627 1.00 76.92 ? 315 LEU A CA 1 ATOM 962 C C . LEU A 1 130 ? -43.388 1.208 39.564 1.00 77.36 ? 315 LEU A C 1 ATOM 963 O O . LEU A 1 130 ? -43.577 2.342 40.004 1.00 77.36 ? 315 LEU A O 1 ATOM 964 C CB . LEU A 1 130 ? -40.925 1.518 39.202 1.00 76.38 ? 315 LEU A CB 1 ATOM 965 C CG . LEU A 1 130 ? -40.383 0.894 40.487 1.00 76.52 ? 315 LEU A CG 1 ATOM 966 C CD1 . LEU A 1 130 ? -39.865 -0.509 40.222 1.00 76.81 ? 315 LEU A CD1 1 ATOM 967 C CD2 . LEU A 1 130 ? -39.286 1.768 41.077 1.00 76.72 ? 315 LEU A CD2 1 ATOM 968 N N . ASN A 1 131 ? -44.165 0.169 39.869 1.00 78.14 ? 316 ASN A N 1 ATOM 969 C CA . ASN A 1 131 ? -45.403 0.303 40.647 1.00 78.82 ? 316 ASN A CA 1 ATOM 970 C C . ASN A 1 131 ? -46.327 1.400 40.099 1.00 78.61 ? 316 ASN A C 1 ATOM 971 O O . ASN A 1 131 ? -46.815 2.251 40.846 1.00 78.08 ? 316 ASN A O 1 ATOM 972 C CB . ASN A 1 131 ? -45.094 0.540 42.134 1.00 79.97 ? 316 ASN A CB 1 ATOM 973 C CG . ASN A 1 131 ? -44.533 -0.698 42.828 1.00 81.12 ? 316 ASN A CG 1 ATOM 974 O OD1 . ASN A 1 131 ? -44.496 -1.789 42.257 1.00 81.32 ? 316 ASN A OD1 1 ATOM 975 N ND2 . ASN A 1 131 ? -44.102 -0.528 44.074 1.00 81.80 ? 316 ASN A ND2 1 ATOM 976 N N . GLY A 1 132 ? -46.556 1.367 38.788 1.00 79.34 ? 317 GLY A N 1 ATOM 977 C CA . GLY A 1 132 ? -47.431 2.333 38.120 1.00 80.29 ? 317 GLY A CA 1 ATOM 978 C C . GLY A 1 132 ? -46.854 3.738 38.022 1.00 81.25 ? 317 GLY A C 1 ATOM 979 O O . GLY A 1 132 ? -47.598 4.706 37.848 1.00 81.35 ? 317 GLY A O 1 ATOM 980 N N . VAL A 1 133 ? -45.530 3.848 38.131 1.00 81.69 ? 318 VAL A N 1 ATOM 981 C CA . VAL A 1 133 ? -44.837 5.134 38.042 1.00 81.39 ? 318 VAL A CA 1 ATOM 982 C C . VAL A 1 133 ? -43.620 4.994 37.120 1.00 82.30 ? 318 VAL A C 1 ATOM 983 O O . VAL A 1 133 ? -42.729 4.188 37.394 1.00 82.88 ? 318 VAL A O 1 ATOM 984 C CB . VAL A 1 133 ? -44.358 5.618 39.429 1.00 81.07 ? 318 VAL A CB 1 ATOM 985 C CG1 . VAL A 1 133 ? -43.753 7.011 39.325 1.00 80.97 ? 318 VAL A CG1 1 ATOM 986 C CG2 . VAL A 1 133 ? -45.507 5.607 40.427 1.00 80.93 ? 318 VAL A CG2 1 ATOM 987 N N . PRO A 1 134 ? -43.575 5.770 36.020 1.00 82.39 ? 319 PRO A N 1 ATOM 988 C CA . PRO A 1 134 ? -44.552 6.771 35.596 1.00 82.73 ? 319 PRO A CA 1 ATOM 989 C C . PRO A 1 134 ? -45.790 6.144 34.957 1.00 82.93 ? 319 PRO A C 1 ATOM 990 O O . PRO A 1 134 ? -45.705 5.060 34.376 1.00 82.97 ? 319 PRO A O 1 ATOM 991 C CB . PRO A 1 134 ? -43.778 7.585 34.559 1.00 82.59 ? 319 PRO A CB 1 ATOM 992 C CG . PRO A 1 134 ? -42.831 6.614 33.964 1.00 82.47 ? 319 PRO A CG 1 ATOM 993 C CD . PRO A 1 134 ? -42.455 5.664 35.066 1.00 82.27 ? 319 PRO A CD 1 ATOM 994 N N . ALA A 1 135 ? -46.929 6.824 35.077 1.00 82.99 ? 320 ALA A N 1 ATOM 995 C CA . ALA A 1 135 ? -48.151 6.414 34.388 1.00 83.07 ? 320 ALA A CA 1 ATOM 996 C C . ALA A 1 135 ? -47.975 6.661 32.893 1.00 83.40 ? 320 ALA A C 1 ATOM 997 O O . ALA A 1 135 ? -47.618 7.768 32.485 1.00 83.72 ? 320 ALA A O 1 ATOM 998 C CB . ALA A 1 135 ? -49.348 7.184 34.919 1.00 83.11 ? 320 ALA A CB 1 ATOM 999 N N . GLN A 1 136 ? -48.237 5.628 32.091 1.00 83.34 ? 321 GLN A N 1 ATOM 1000 C CA . GLN A 1 136 ? -47.842 5.583 30.675 1.00 83.14 ? 321 GLN A CA 1 ATOM 1001 C C . GLN A 1 136 ? -46.313 5.487 30.582 1.00 83.32 ? 321 GLN A C 1 ATOM 1002 O O . GLN A 1 136 ? -45.610 6.434 30.936 1.00 83.67 ? 321 GLN A O 1 ATOM 1003 C CB . GLN A 1 136 ? -48.360 6.798 29.889 1.00 83.04 ? 321 GLN A CB 1 ATOM 1004 C CG . GLN A 1 136 ? -49.854 7.069 30.058 1.00 83.12 ? 321 GLN A CG 1 ATOM 1005 C CD . GLN A 1 136 ? -50.318 8.315 29.318 1.00 83.21 ? 321 GLN A CD 1 ATOM 1006 O OE1 . GLN A 1 136 ? -49.571 8.907 28.538 1.00 83.28 ? 321 GLN A OE1 1 ATOM 1007 N NE2 . GLN A 1 136 ? -51.561 8.716 29.562 1.00 83.25 ? 321 GLN A NE2 1 ATOM 1008 N N . PRO A 1 137 ? -45.793 4.338 30.107 1.00 83.12 ? 322 PRO A N 1 ATOM 1009 C CA . PRO A 1 137 ? -44.354 4.063 30.199 1.00 82.84 ? 322 PRO A CA 1 ATOM 1010 C C . PRO A 1 137 ? -43.488 4.979 29.324 1.00 82.48 ? 322 PRO A C 1 ATOM 1011 O O . PRO A 1 137 ? -43.841 5.260 28.176 1.00 82.17 ? 322 PRO A O 1 ATOM 1012 C CB . PRO A 1 137 ? -44.246 2.603 29.740 1.00 83.01 ? 322 PRO A CB 1 ATOM 1013 C CG . PRO A 1 137 ? -45.426 2.387 28.874 1.00 83.21 ? 322 PRO A CG 1 ATOM 1014 C CD . PRO A 1 137 ? -46.520 3.241 29.441 1.00 83.17 ? 322 PRO A CD 1 ATOM 1015 N N . LEU A 1 138 ? -42.369 5.440 29.884 1.00 82.32 ? 323 LEU A N 1 ATOM 1016 C CA . LEU A 1 138 ? -41.456 6.357 29.198 1.00 82.13 ? 323 LEU A CA 1 ATOM 1017 C C . LEU A 1 138 ? -40.011 6.071 29.607 1.00 82.26 ? 323 LEU A C 1 ATOM 1018 O O . LEU A 1 138 ? -39.663 6.188 30.783 1.00 82.90 ? 323 LEU A O 1 ATOM 1019 C CB . LEU A 1 138 ? -41.800 7.807 29.551 1.00 82.32 ? 323 LEU A CB 1 ATOM 1020 C CG . LEU A 1 138 ? -43.186 8.315 29.146 1.00 82.37 ? 323 LEU A CG 1 ATOM 1021 C CD1 . LEU A 1 138 ? -43.544 9.573 29.920 1.00 82.28 ? 323 LEU A CD1 1 ATOM 1022 C CD2 . LEU A 1 138 ? -43.252 8.557 27.646 1.00 82.45 ? 323 LEU A CD2 1 ATOM 1023 N N . GLY A 1 139 ? -39.178 5.691 28.640 1.00 81.56 ? 324 GLY A N 1 ATOM 1024 C CA . GLY A 1 139 ? -37.762 5.412 28.900 1.00 81.00 ? 324 GLY A CA 1 ATOM 1025 C C . GLY A 1 139 ? -37.527 4.056 29.554 1.00 80.39 ? 324 GLY A C 1 ATOM 1026 O O . GLY A 1 139 ? -38.423 3.514 30.203 1.00 80.20 ? 324 GLY A O 1 ATOM 1027 N N . PRO A 1 140 ? -36.303 3.510 29.413 1.00 80.04 ? 325 PRO A N 1 ATOM 1028 C CA . PRO A 1 140 ? -36.021 2.124 29.797 1.00 79.79 ? 325 PRO A CA 1 ATOM 1029 C C . PRO A 1 140 ? -35.766 1.869 31.289 1.00 79.56 ? 325 PRO A C 1 ATOM 1030 O O . PRO A 1 140 ? -35.592 0.711 31.678 1.00 79.57 ? 325 PRO A O 1 ATOM 1031 C CB . PRO A 1 140 ? -34.758 1.805 28.995 1.00 79.80 ? 325 PRO A CB 1 ATOM 1032 C CG . PRO A 1 140 ? -34.040 3.104 28.928 1.00 79.89 ? 325 PRO A CG 1 ATOM 1033 C CD . PRO A 1 140 ? -35.101 4.180 28.879 1.00 79.90 ? 325 PRO A CD 1 ATOM 1034 N N . ARG A 1 141 ? -35.740 2.916 32.115 1.00 79.11 ? 326 ARG A N 1 ATOM 1035 C CA . ARG A 1 141 ? -35.474 2.743 33.550 1.00 78.57 ? 326 ARG A CA 1 ATOM 1036 C C . ARG A 1 141 ? -36.128 3.810 34.431 1.00 77.31 ? 326 ARG A C 1 ATOM 1037 O O . ARG A 1 141 ? -36.238 4.974 34.039 1.00 76.95 ? 326 ARG A O 1 ATOM 1038 C CB . ARG A 1 141 ? -33.965 2.681 33.812 1.00 78.92 ? 326 ARG A CB 1 ATOM 1039 C CG . ARG A 1 141 ? -33.179 3.851 33.246 1.00 79.45 ? 326 ARG A CG 1 ATOM 1040 C CD . ARG A 1 141 ? -31.733 3.469 32.962 1.00 79.91 ? 326 ARG A CD 1 ATOM 1041 N NE . ARG A 1 141 ? -30.938 3.329 34.180 1.00 80.43 ? 326 ARG A NE 1 ATOM 1042 C CZ . ARG A 1 141 ? -29.634 3.056 34.204 1.00 80.82 ? 326 ARG A CZ 1 ATOM 1043 N NH1 . ARG A 1 141 ? -28.955 2.884 33.072 1.00 80.90 ? 326 ARG A NH1 1 ATOM 1044 N NH2 . ARG A 1 141 ? -29.001 2.952 35.369 1.00 80.83 ? 326 ARG A NH2 1 ATOM 1045 N N . ALA A 1 142 ? -36.550 3.392 35.627 1.00 76.42 ? 327 ALA A N 1 ATOM 1046 C CA . ALA A 1 142 ? -37.280 4.256 36.556 1.00 76.27 ? 327 ALA A CA 1 ATOM 1047 C C . ALA A 1 142 ? -36.774 4.094 37.992 1.00 75.74 ? 327 ALA A C 1 ATOM 1048 O O . ALA A 1 142 ? -36.289 3.027 38.373 1.00 75.32 ? 327 ALA A O 1 ATOM 1049 C CB . ALA A 1 142 ? -38.767 3.955 36.489 1.00 75.64 ? 327 ALA A CB 1 ATOM 1050 N N . GLN A 1 143 ? -36.906 5.164 38.778 1.00 75.47 ? 328 GLN A N 1 ATOM 1051 C CA . GLN A 1 143 ? -36.445 5.198 40.169 1.00 75.18 ? 328 GLN A CA 1 ATOM 1052 C C . GLN A 1 143 ? -37.608 5.379 41.143 1.00 74.35 ? 328 GLN A C 1 ATOM 1053 O O . GLN A 1 143 ? -38.727 5.698 40.739 1.00 73.94 ? 328 GLN A O 1 ATOM 1054 C CB . GLN A 1 143 ? -35.447 6.344 40.367 1.00 75.42 ? 328 GLN A CB 1 ATOM 1055 C CG . GLN A 1 143 ? -33.993 5.967 40.143 1.00 75.26 ? 328 GLN A CG 1 ATOM 1056 C CD . GLN A 1 143 ? -33.038 7.043 40.626 1.00 74.95 ? 328 GLN A CD 1 ATOM 1057 O OE1 . GLN A 1 143 ? -32.112 6.770 41.390 1.00 74.49 ? 328 GLN A OE1 1 ATOM 1058 N NE2 . GLN A 1 143 ? -33.268 8.277 40.192 1.00 75.05 ? 328 GLN A NE2 1 ATOM 1059 N N . LEU A 1 144 ? -37.325 5.181 42.428 1.00 74.34 ? 329 LEU A N 1 ATOM 1060 C CA . LEU A 1 144 ? -38.303 5.424 43.489 1.00 74.80 ? 329 LEU A CA 1 ATOM 1061 C C . LEU A 1 144 ? -37.608 5.519 44.848 1.00 74.57 ? 329 LEU A C 1 ATOM 1062 O O . LEU A 1 144 ? -37.075 4.527 45.344 1.00 74.48 ? 329 LEU A O 1 ATOM 1063 C CB . LEU A 1 144 ? -39.356 4.309 43.513 1.00 74.94 ? 329 LEU A CB 1 ATOM 1064 C CG . LEU A 1 144 ? -40.456 4.395 44.578 1.00 74.67 ? 329 LEU A CG 1 ATOM 1065 C CD1 . LEU A 1 144 ? -41.092 5.778 44.618 1.00 74.41 ? 329 LEU A CD1 1 ATOM 1066 C CD2 . LEU A 1 144 ? -41.511 3.327 44.326 1.00 74.87 ? 329 LEU A CD2 1 ATOM 1067 N N . LEU A 1 145 ? -37.612 6.714 45.437 1.00 74.81 ? 330 LEU A N 1 ATOM 1068 C CA . LEU A 1 145 ? -37.030 6.933 46.764 1.00 75.30 ? 330 LEU A CA 1 ATOM 1069 C C . LEU A 1 145 ? -38.085 6.711 47.843 1.00 75.33 ? 330 LEU A C 1 ATOM 1070 O O . LEU A 1 145 ? -39.251 7.063 47.657 1.00 75.19 ? 330 LEU A O 1 ATOM 1071 C CB . LEU A 1 145 ? -36.471 8.355 46.882 1.00 75.70 ? 330 LEU A CB 1 ATOM 1072 C CG . LEU A 1 145 ? -35.529 8.830 45.772 1.00 75.86 ? 330 LEU A CG 1 ATOM 1073 C CD1 . LEU A 1 145 ? -35.032 10.237 46.075 1.00 75.65 ? 330 LEU A CD1 1 ATOM 1074 C CD2 . LEU A 1 145 ? -34.360 7.872 45.594 1.00 75.94 ? 330 LEU A CD2 1 ATOM 1075 N N . LEU A 1 146 ? -37.671 6.135 48.970 1.00 75.64 ? 331 LEU A N 1 ATOM 1076 C CA . LEU A 1 146 ? -38.584 5.875 50.084 1.00 76.09 ? 331 LEU A CA 1 ATOM 1077 C C . LEU A 1 146 ? -37.878 5.905 51.434 1.00 76.52 ? 331 LEU A C 1 ATOM 1078 O O . LEU A 1 146 ? -36.795 5.340 51.593 1.00 76.63 ? 331 LEU A O 1 ATOM 1079 C CB . LEU A 1 146 ? -39.269 4.516 49.912 1.00 76.81 ? 331 LEU A CB 1 ATOM 1080 C CG . LEU A 1 146 ? -40.556 4.482 49.086 1.00 77.46 ? 331 LEU A CG 1 ATOM 1081 C CD1 . LEU A 1 146 ? -41.046 3.049 48.950 1.00 77.35 ? 331 LEU A CD1 1 ATOM 1082 C CD2 . LEU A 1 146 ? -41.634 5.368 49.708 1.00 77.34 ? 331 LEU A CD2 1 ATOM 1083 N N . LYS A 1 147 ? -38.508 6.570 52.400 1.00 76.69 ? 332 LYS A N 1 ATOM 1084 C CA . LYS A 1 147 ? -38.116 6.474 53.801 1.00 76.45 ? 332 LYS A CA 1 ATOM 1085 C C . LYS A 1 147 ? -38.665 5.152 54.347 1.00 76.46 ? 332 LYS A C 1 ATOM 1086 O O . LYS A 1 147 ? -39.881 4.976 54.445 1.00 76.77 ? 332 LYS A O 1 ATOM 1087 C CB . LYS A 1 147 ? -38.683 7.660 54.590 1.00 76.47 ? 332 LYS A CB 1 ATOM 1088 C CG . LYS A 1 147 ? -38.121 7.819 55.997 1.00 76.58 ? 332 LYS A CG 1 ATOM 1089 C CD . LYS A 1 147 ? -36.707 8.377 55.979 1.00 76.61 ? 332 LYS A CD 1 ATOM 1090 C CE . LYS A 1 147 ? -36.251 8.780 57.373 1.00 76.57 ? 332 LYS A CE 1 ATOM 1091 N NZ . LYS A 1 147 ? -34.927 9.460 57.355 1.00 76.58 ? 332 LYS A NZ 1 ATOM 1092 N N . ALA A 1 148 ? -37.773 4.223 54.685 1.00 76.24 ? 333 ALA A N 1 ATOM 1093 C CA . ALA A 1 148 ? -38.184 2.888 55.129 1.00 76.34 ? 333 ALA A CA 1 ATOM 1094 C C . ALA A 1 148 ? -38.974 2.949 56.437 1.00 76.62 ? 333 ALA A C 1 ATOM 1095 O O . ALA A 1 148 ? -38.565 3.617 57.389 1.00 76.51 ? 333 ALA A O 1 ATOM 1096 C CB . ALA A 1 148 ? -36.972 1.985 55.287 1.00 75.87 ? 333 ALA A CB 1 ATOM 1097 N N . THR A 1 149 ? -40.108 2.252 56.464 1.00 76.75 ? 334 THR A N 1 ATOM 1098 C CA . THR A 1 149 ? -40.977 2.190 57.640 1.00 76.82 ? 334 THR A CA 1 ATOM 1099 C C . THR A 1 149 ? -41.411 0.739 57.872 1.00 77.21 ? 334 THR A C 1 ATOM 1100 O O . THR A 1 149 ? -41.268 -0.097 56.978 1.00 77.58 ? 334 THR A O 1 ATOM 1101 C CB . THR A 1 149 ? -42.228 3.073 57.454 1.00 76.65 ? 334 THR A CB 1 ATOM 1102 O OG1 . THR A 1 149 ? -42.941 2.658 56.282 1.00 76.99 ? 334 THR A OG1 1 ATOM 1103 C CG2 . THR A 1 149 ? -41.838 4.536 57.318 1.00 76.30 ? 334 THR A CG2 1 ATOM 1104 N N . PRO A 1 150 ? -41.941 0.430 59.072 1.00 77.13 ? 335 PRO A N 1 ATOM 1105 C CA . PRO A 1 150 ? -42.403 -0.933 59.352 1.00 77.28 ? 335 PRO A CA 1 ATOM 1106 C C . PRO A 1 150 ? -43.420 -1.469 58.340 1.00 77.91 ? 335 PRO A C 1 ATOM 1107 O O . PRO A 1 150 ? -43.444 -2.672 58.072 1.00 78.41 ? 335 PRO A O 1 ATOM 1108 C CB . PRO A 1 150 ? -43.046 -0.806 60.736 1.00 77.21 ? 335 PRO A CB 1 ATOM 1109 C CG . PRO A 1 150 ? -42.364 0.348 61.360 1.00 77.31 ? 335 PRO A CG 1 ATOM 1110 C CD . PRO A 1 150 ? -42.118 1.310 60.242 1.00 77.36 ? 335 PRO A CD 1 ATOM 1111 N N . GLU A 1 151 ? -44.240 -0.580 57.782 1.00 77.96 ? 336 GLU A N 1 ATOM 1112 C CA . GLU A 1 151 ? -45.241 -0.964 56.783 1.00 77.75 ? 336 GLU A CA 1 ATOM 1113 C C . GLU A 1 151 ? -44.598 -1.398 55.460 1.00 77.65 ? 336 GLU A C 1 ATOM 1114 O O . GLU A 1 151 ? -45.234 -2.077 54.654 1.00 77.59 ? 336 GLU A O 1 ATOM 1115 C CB . GLU A 1 151 ? -46.226 0.188 56.529 1.00 79.00 ? 336 GLU A CB 1 ATOM 1116 C CG . GLU A 1 151 ? -47.294 0.366 57.617 1.00 80.30 ? 336 GLU A CG 1 ATOM 1117 C CD . GLU A 1 151 ? -46.741 0.890 58.938 1.00 81.53 ? 336 GLU A CD 1 ATOM 1118 O OE1 . GLU A 1 151 ? -45.624 1.452 58.951 1.00 81.83 ? 336 GLU A OE1 1 ATOM 1119 O OE2 . GLU A 1 151 ? -47.432 0.744 59.970 1.00 82.25 ? 336 GLU A OE2 1 ATOM 1120 N N . ASP A 1 152 ? -43.342 -1.007 55.246 1.00 77.50 ? 337 ASP A N 1 ATOM 1121 C CA . ASP A 1 152 ? -42.610 -1.367 54.031 1.00 76.96 ? 337 ASP A CA 1 ATOM 1122 C C . ASP A 1 152 ? -41.975 -2.755 54.109 1.00 76.07 ? 337 ASP A C 1 ATOM 1123 O O . ASP A 1 152 ? -41.423 -3.233 53.120 1.00 76.17 ? 337 ASP A O 1 ATOM 1124 C CB . ASP A 1 152 ? -41.524 -0.326 53.733 1.00 78.16 ? 337 ASP A CB 1 ATOM 1125 C CG . ASP A 1 152 ? -42.080 1.084 53.613 1.00 79.46 ? 337 ASP A CG 1 ATOM 1126 O OD1 . ASP A 1 152 ? -43.169 1.247 53.022 1.00 80.08 ? 337 ASP A OD1 1 ATOM 1127 O OD2 . ASP A 1 152 ? -41.427 2.030 54.110 1.00 79.42 ? 337 ASP A OD2 1 ATOM 1128 N N . ASN A 1 153 ? -42.038 -3.398 55.275 1.00 75.60 ? 338 ASN A N 1 ATOM 1129 C CA . ASN A 1 153 ? -41.528 -4.761 55.414 1.00 75.65 ? 338 ASN A CA 1 ATOM 1130 C C . ASN A 1 153 ? -42.403 -5.733 54.634 1.00 74.57 ? 338 ASN A C 1 ATOM 1131 O O . ASN A 1 153 ? -43.598 -5.848 54.897 1.00 74.12 ? 338 ASN A O 1 ATOM 1132 C CB . ASN A 1 153 ? -41.462 -5.186 56.886 1.00 75.64 ? 338 ASN A CB 1 ATOM 1133 C CG . ASN A 1 153 ? -40.828 -6.561 57.072 1.00 75.36 ? 338 ASN A CG 1 ATOM 1134 O OD1 . ASN A 1 153 ? -39.926 -6.951 56.327 1.00 74.99 ? 338 ASN A OD1 1 ATOM 1135 N ND2 . ASN A 1 153 ? -41.298 -7.298 58.069 1.00 75.43 ? 338 ASN A ND2 1 ATOM 1136 N N . GLY A 1 154 ? -41.800 -6.421 53.669 1.00 74.74 ? 339 GLY A N 1 ATOM 1137 C CA . GLY A 1 154 ? -42.526 -7.335 52.795 1.00 75.11 ? 339 GLY A CA 1 ATOM 1138 C C . GLY A 1 154 ? -43.248 -6.637 51.656 1.00 74.29 ? 339 GLY A C 1 ATOM 1139 O O . GLY A 1 154 ? -44.036 -7.262 50.947 1.00 73.72 ? 339 GLY A O 1 ATOM 1140 N N . ARG A 1 155 ? -42.975 -5.344 51.473 1.00 74.80 ? 340 ARG A N 1 ATOM 1141 C CA . ARG A 1 155 ? -43.592 -4.567 50.400 1.00 75.73 ? 340 ARG A CA 1 ATOM 1142 C C . ARG A 1 155 ? -42.977 -4.952 49.063 1.00 75.88 ? 340 ARG A C 1 ATOM 1143 O O . ARG A 1 155 ? -41.762 -4.861 48.887 1.00 75.25 ? 340 ARG A O 1 ATOM 1144 C CB . ARG A 1 155 ? -43.406 -3.065 50.645 1.00 75.21 ? 340 ARG A CB 1 ATOM 1145 C CG . ARG A 1 155 ? -43.885 -2.175 49.504 1.00 75.00 ? 340 ARG A CG 1 ATOM 1146 C CD . ARG A 1 155 ? -43.860 -0.705 49.893 1.00 75.23 ? 340 ARG A CD 1 ATOM 1147 N NE . ARG A 1 155 ? -43.935 0.173 48.725 1.00 75.31 ? 340 ARG A NE 1 ATOM 1148 C CZ . ARG A 1 155 ? -44.008 1.502 48.779 1.00 75.16 ? 340 ARG A CZ 1 ATOM 1149 N NH1 . ARG A 1 155 ? -44.022 2.136 49.947 1.00 75.06 ? 340 ARG A NH1 1 ATOM 1150 N NH2 . ARG A 1 155 ? -44.069 2.206 47.655 1.00 75.15 ? 340 ARG A NH2 1 ATOM 1151 N N . SER A 1 156 ? -43.820 -5.381 48.127 1.00 77.09 ? 341 SER A N 1 ATOM 1152 C CA . SER A 1 156 ? -43.360 -5.773 46.796 1.00 78.42 ? 341 SER A CA 1 ATOM 1153 C C . SER A 1 156 ? -43.153 -4.547 45.913 1.00 78.72 ? 341 SER A C 1 ATOM 1154 O O . SER A 1 156 ? -43.935 -3.594 45.963 1.00 78.59 ? 341 SER A O 1 ATOM 1155 C CB . SER A 1 156 ? -44.364 -6.720 46.137 1.00 80.00 ? 341 SER A CB 1 ATOM 1156 O OG . SER A 1 156 ? -45.625 -6.094 45.979 1.00 81.50 ? 341 SER A OG 1 ATOM 1157 N N . PHE A 1 157 ? -42.088 -4.576 45.116 1.00 79.17 ? 342 PHE A N 1 ATOM 1158 C CA . PHE A 1 157 ? -41.820 -3.530 44.136 1.00 79.75 ? 342 PHE A CA 1 ATOM 1159 C C . PHE A 1 157 ? -41.818 -4.136 42.740 1.00 80.33 ? 342 PHE A C 1 ATOM 1160 O O . PHE A 1 157 ? -40.811 -4.686 42.292 1.00 80.75 ? 342 PHE A O 1 ATOM 1161 C CB . PHE A 1 157 ? -40.488 -2.846 44.431 1.00 79.38 ? 342 PHE A CB 1 ATOM 1162 C CG . PHE A 1 157 ? -40.531 -1.947 45.629 1.00 79.46 ? 342 PHE A CG 1 ATOM 1163 C CD1 . PHE A 1 157 ? -41.098 -0.681 45.540 1.00 79.44 ? 342 PHE A CD1 1 ATOM 1164 C CD2 . PHE A 1 157 ? -40.017 -2.366 46.849 1.00 79.52 ? 342 PHE A CD2 1 ATOM 1165 C CE1 . PHE A 1 157 ? -41.146 0.156 46.646 1.00 79.32 ? 342 PHE A CE1 1 ATOM 1166 C CE2 . PHE A 1 157 ? -40.062 -1.534 47.961 1.00 79.41 ? 342 PHE A CE2 1 ATOM 1167 C CZ . PHE A 1 157 ? -40.628 -0.273 47.858 1.00 79.33 ? 342 PHE A CZ 1 ATOM 1168 N N . SER A 1 158 ? -42.961 -4.040 42.066 1.00 80.64 ? 343 SER A N 1 ATOM 1169 C CA . SER A 1 158 ? -43.134 -4.632 40.746 1.00 81.18 ? 343 SER A CA 1 ATOM 1170 C C . SER A 1 158 ? -42.676 -3.666 39.661 1.00 81.64 ? 343 SER A C 1 ATOM 1171 O O . SER A 1 158 ? -42.848 -2.453 39.785 1.00 81.48 ? 343 SER A O 1 ATOM 1172 C CB . SER A 1 158 ? -44.598 -5.010 40.520 1.00 81.98 ? 343 SER A CB 1 ATOM 1173 O OG . SER A 1 158 ? -45.077 -5.834 41.570 1.00 82.82 ? 343 SER A OG 1 ATOM 1174 N N . CYS A 1 159 ? -42.090 -4.215 38.602 1.00 82.65 ? 344 CYS A N 1 ATOM 1175 C CA . CYS A 1 159 ? -41.682 -3.425 37.449 1.00 81.79 ? 344 CYS A CA 1 ATOM 1176 C C . CYS A 1 159 ? -42.212 -4.044 36.164 1.00 80.96 ? 344 CYS A C 1 ATOM 1177 O O . CYS A 1 159 ? -41.901 -5.189 35.857 1.00 80.31 ? 344 CYS A O 1 ATOM 1178 C CB . CYS A 1 159 ? -40.165 -3.334 37.373 1.00 83.36 ? 344 CYS A CB 1 ATOM 1179 S SG . CYS A 1 159 ? -39.596 -2.314 36.004 1.00 85.44 ? 344 CYS A SG 1 ATOM 1180 N N . SER A 1 160 ? -43.003 -3.277 35.417 1.00 80.77 ? 345 SER A N 1 ATOM 1181 C CA . SER A 1 160 ? -43.550 -3.732 34.142 1.00 80.68 ? 345 SER A CA 1 ATOM 1182 C C . SER A 1 160 ? -42.828 -3.042 32.993 1.00 80.58 ? 345 SER A C 1 ATOM 1183 O O . SER A 1 160 ? -42.696 -1.819 32.986 1.00 81.42 ? 345 SER A O 1 ATOM 1184 C CB . SER A 1 160 ? -45.048 -3.432 34.068 1.00 81.08 ? 345 SER A CB 1 ATOM 1185 O OG . SER A 1 160 ? -45.762 -4.170 35.044 1.00 81.58 ? 345 SER A OG 1 ATOM 1186 N N . ALA A 1 161 ? -42.360 -3.832 32.029 1.00 79.63 ? 346 ALA A N 1 ATOM 1187 C CA . ALA A 1 161 ? -41.681 -3.302 30.850 1.00 79.15 ? 346 ALA A CA 1 ATOM 1188 C C . ALA A 1 161 ? -42.419 -3.708 29.580 1.00 78.61 ? 346 ALA A C 1 ATOM 1189 O O . ALA A 1 161 ? -43.066 -4.758 29.534 1.00 77.57 ? 346 ALA A O 1 ATOM 1190 C CB . ALA A 1 161 ? -40.247 -3.789 30.802 1.00 78.58 ? 346 ALA A CB 1 ATOM 1191 N N . THR A 1 162 ? -42.312 -2.862 28.556 1.00 78.97 ? 347 THR A N 1 ATOM 1192 C CA . THR A 1 162 ? -42.943 -3.102 27.261 1.00 78.55 ? 347 THR A CA 1 ATOM 1193 C C . THR A 1 162 ? -41.939 -2.851 26.141 1.00 78.13 ? 347 THR A C 1 ATOM 1194 O O . THR A 1 162 ? -41.307 -1.795 26.096 1.00 78.14 ? 347 THR A O 1 ATOM 1195 C CB . THR A 1 162 ? -44.160 -2.179 27.051 1.00 79.04 ? 347 THR A CB 1 ATOM 1196 O OG1 . THR A 1 162 ? -45.180 -2.504 28.003 1.00 79.41 ? 347 THR A OG1 1 ATOM 1197 C CG2 . THR A 1 162 ? -44.721 -2.329 25.639 1.00 79.19 ? 347 THR A CG2 1 ATOM 1198 N N . LEU A 1 163 ? -41.802 -3.824 25.242 1.00 77.85 ? 348 LEU A N 1 ATOM 1199 C CA . LEU A 1 163 ? -40.884 -3.718 24.110 1.00 77.69 ? 348 LEU A CA 1 ATOM 1200 C C . LEU A 1 163 ? -41.645 -3.839 22.792 1.00 77.40 ? 348 LEU A C 1 ATOM 1201 O O . LEU A 1 163 ? -42.417 -4.780 22.597 1.00 76.80 ? 348 LEU A O 1 ATOM 1202 C CB . LEU A 1 163 ? -39.804 -4.803 24.196 1.00 77.60 ? 348 LEU A CB 1 ATOM 1203 C CG . LEU A 1 163 ? -38.723 -4.801 23.108 1.00 77.64 ? 348 LEU A CG 1 ATOM 1204 C CD1 . LEU A 1 163 ? -38.045 -3.439 22.999 1.00 77.61 ? 348 LEU A CD1 1 ATOM 1205 C CD2 . LEU A 1 163 ? -37.697 -5.889 23.380 1.00 77.48 ? 348 LEU A CD2 1 ATOM 1206 N N . GLU A 1 164 ? -41.419 -2.876 21.899 1.00 77.58 ? 349 GLU A N 1 ATOM 1207 C CA . GLU A 1 164 ? -42.031 -2.871 20.571 1.00 77.17 ? 349 GLU A CA 1 ATOM 1208 C C . GLU A 1 164 ? -41.213 -3.747 19.626 1.00 77.19 ? 349 GLU A C 1 ATOM 1209 O O . GLU A 1 164 ? -40.053 -3.443 19.341 1.00 77.39 ? 349 GLU A O 1 ATOM 1210 C CB . GLU A 1 164 ? -42.099 -1.436 20.032 1.00 77.71 ? 349 GLU A CB 1 ATOM 1211 C CG . GLU A 1 164 ? -42.736 -1.285 18.643 1.00 78.21 ? 349 GLU A CG 1 ATOM 1212 C CD . GLU A 1 164 ? -44.255 -1.215 18.682 1.00 78.94 ? 349 GLU A CD 1 ATOM 1213 O OE1 . GLU A 1 164 ? -44.869 -1.821 19.586 1.00 79.39 ? 349 GLU A OE1 1 ATOM 1214 O OE2 . GLU A 1 164 ? -44.836 -0.552 17.796 1.00 78.94 ? 349 GLU A OE2 1 ATOM 1215 N N . VAL A 1 165 ? -41.822 -4.833 19.146 1.00 76.64 ? 350 VAL A N 1 ATOM 1216 C CA . VAL A 1 165 ? -41.149 -5.774 18.249 1.00 75.86 ? 350 VAL A CA 1 ATOM 1217 C C . VAL A 1 165 ? -42.024 -6.079 17.037 1.00 75.37 ? 350 VAL A C 1 ATOM 1218 O O . VAL A 1 165 ? -43.091 -6.680 17.172 1.00 74.78 ? 350 VAL A O 1 ATOM 1219 C CB . VAL A 1 165 ? -40.819 -7.100 18.964 1.00 75.31 ? 350 VAL A CB 1 ATOM 1220 C CG1 . VAL A 1 165 ? -40.047 -8.028 18.037 1.00 74.87 ? 350 VAL A CG1 1 ATOM 1221 C CG2 . VAL A 1 165 ? -40.032 -6.839 20.238 1.00 75.23 ? 350 VAL A CG2 1 ATOM 1222 N N . ALA A 1 166 ? -41.562 -5.656 15.859 1.00 75.69 ? 351 ALA A N 1 ATOM 1223 C CA . ALA A 1 166 ? -42.266 -5.898 14.596 1.00 75.29 ? 351 ALA A CA 1 ATOM 1224 C C . ALA A 1 166 ? -43.711 -5.395 14.629 1.00 75.00 ? 351 ALA A C 1 ATOM 1225 O O . ALA A 1 166 ? -44.624 -6.074 14.157 1.00 74.91 ? 351 ALA A O 1 ATOM 1226 C CB . ALA A 1 166 ? -42.225 -7.382 14.244 1.00 75.01 ? 351 ALA A CB 1 ATOM 1227 N N . GLY A 1 167 ? -43.907 -4.208 15.197 1.00 75.01 ? 352 GLY A N 1 ATOM 1228 C CA . GLY A 1 167 ? -45.223 -3.577 15.243 1.00 75.31 ? 352 GLY A CA 1 ATOM 1229 C C . GLY A 1 167 ? -46.207 -4.205 16.216 1.00 75.32 ? 352 GLY A C 1 ATOM 1230 O O . GLY A 1 167 ? -47.405 -4.256 15.940 1.00 75.34 ? 352 GLY A O 1 ATOM 1231 N N . GLN A 1 168 ? -45.711 -4.687 17.354 1.00 75.43 ? 353 GLN A N 1 ATOM 1232 C CA . GLN A 1 168 ? -46.589 -5.151 18.433 1.00 75.69 ? 353 GLN A CA 1 ATOM 1233 C C . GLN A 1 168 ? -45.894 -5.100 19.793 1.00 75.98 ? 353 GLN A C 1 ATOM 1234 O O . GLN A 1 168 ? -44.694 -5.357 19.900 1.00 75.99 ? 353 GLN A O 1 ATOM 1235 C CB . GLN A 1 168 ? -47.123 -6.562 18.152 1.00 75.48 ? 353 GLN A CB 1 ATOM 1236 C CG . GLN A 1 168 ? -46.064 -7.615 17.857 1.00 75.23 ? 353 GLN A CG 1 ATOM 1237 C CD . GLN A 1 168 ? -46.631 -9.026 17.884 1.00 75.27 ? 353 GLN A CD 1 ATOM 1238 O OE1 . GLN A 1 168 ? -46.723 -9.692 16.854 1.00 75.07 ? 353 GLN A OE1 1 ATOM 1239 N NE2 . GLN A 1 168 ? -47.025 -9.481 19.066 1.00 75.64 ? 353 GLN A NE2 1 ATOM 1240 N N . LEU A 1 169 ? -46.668 -4.767 20.825 1.00 76.24 ? 354 LEU A N 1 ATOM 1241 C CA . LEU A 1 169 ? -46.136 -4.550 22.170 1.00 76.42 ? 354 LEU A CA 1 ATOM 1242 C C . LEU A 1 169 ? -46.029 -5.862 22.945 1.00 76.28 ? 354 LEU A C 1 ATOM 1243 O O . LEU A 1 169 ? -47.039 -6.513 23.215 1.00 75.99 ? 354 LEU A O 1 ATOM 1244 C CB . LEU A 1 169 ? -47.031 -3.572 22.939 1.00 77.22 ? 354 LEU A CB 1 ATOM 1245 C CG . LEU A 1 169 ? -47.169 -2.172 22.333 1.00 78.01 ? 354 LEU A CG 1 ATOM 1246 C CD1 . LEU A 1 169 ? -48.356 -1.433 22.933 1.00 78.36 ? 354 LEU A CD1 1 ATOM 1247 C CD2 . LEU A 1 169 ? -45.886 -1.377 22.523 1.00 78.23 ? 354 LEU A CD2 1 ATOM 1248 N N . ILE A 1 170 ? -44.800 -6.238 23.297 1.00 76.48 ? 355 ILE A N 1 ATOM 1249 C CA . ILE A 1 170 ? -44.552 -7.405 24.145 1.00 76.62 ? 355 ILE A CA 1 ATOM 1250 C C . ILE A 1 170 ? -44.399 -6.929 25.584 1.00 76.52 ? 355 ILE A C 1 ATOM 1251 O O . ILE A 1 170 ? -43.756 -5.912 25.836 1.00 76.47 ? 355 ILE A O 1 ATOM 1252 C CB . ILE A 1 170 ? -43.273 -8.164 23.722 1.00 76.64 ? 355 ILE A CB 1 ATOM 1253 C CG1 . ILE A 1 170 ? -43.255 -8.406 22.208 1.00 77.33 ? 355 ILE A CG1 1 ATOM 1254 C CG2 . ILE A 1 170 ? -43.170 -9.485 24.463 1.00 76.37 ? 355 ILE A CG2 1 ATOM 1255 C CD1 . ILE A 1 170 ? -44.505 -9.082 21.673 1.00 77.84 ? 355 ILE A CD1 1 ATOM 1256 N N . HIS A 1 171 ? -44.988 -7.667 26.522 1.00 76.67 ? 356 HIS A N 1 ATOM 1257 C CA . HIS A 1 171 ? -45.012 -7.266 27.929 1.00 77.19 ? 356 HIS A CA 1 ATOM 1258 C C . HIS A 1 171 ? -44.254 -8.257 28.812 1.00 77.65 ? 356 HIS A C 1 ATOM 1259 O O . HIS A 1 171 ? -44.358 -9.472 28.633 1.00 77.98 ? 356 HIS A O 1 ATOM 1260 C CB . HIS A 1 171 ? -46.455 -7.155 28.423 1.00 77.64 ? 356 HIS A CB 1 ATOM 1261 C CG . HIS A 1 171 ? -47.295 -6.198 27.635 1.00 77.98 ? 356 HIS A CG 1 ATOM 1262 N ND1 . HIS A 1 171 ? -47.505 -4.894 28.028 1.00 78.28 ? 356 HIS A ND1 1 ATOM 1263 C CD2 . HIS A 1 171 ? -47.982 -6.357 26.479 1.00 78.17 ? 356 HIS A CD2 1 ATOM 1264 C CE1 . HIS A 1 171 ? -48.283 -4.290 27.148 1.00 78.27 ? 356 HIS A CE1 1 ATOM 1265 N NE2 . HIS A 1 171 ? -48.587 -5.156 26.198 1.00 78.38 ? 356 HIS A NE2 1 ATOM 1266 N N . LYS A 1 172 ? -43.492 -7.721 29.762 1.00 77.63 ? 357 LYS A N 1 ATOM 1267 C CA . LYS A 1 172 ? -42.845 -8.522 30.801 1.00 77.63 ? 357 LYS A CA 1 ATOM 1268 C C . LYS A 1 172 ? -42.850 -7.753 32.115 1.00 77.09 ? 357 LYS A C 1 ATOM 1269 O O . LYS A 1 172 ? -42.930 -6.525 32.119 1.00 76.74 ? 357 LYS A O 1 ATOM 1270 C CB . LYS A 1 172 ? -41.406 -8.859 30.409 1.00 77.53 ? 357 LYS A CB 1 ATOM 1271 C CG . LYS A 1 172 ? -41.281 -10.007 29.419 1.00 77.57 ? 357 LYS A CG 1 ATOM 1272 C CD . LYS A 1 172 ? -39.847 -10.518 29.345 1.00 77.83 ? 357 LYS A CD 1 ATOM 1273 C CE . LYS A 1 172 ? -39.738 -11.768 28.484 1.00 77.84 ? 357 LYS A CE 1 ATOM 1274 N NZ . LYS A 1 172 ? -38.387 -12.394 28.564 1.00 77.61 ? 357 LYS A NZ 1 ATOM 1275 N N . ASN A 1 173 ? -42.779 -8.475 33.230 1.00 77.43 ? 358 ASN A N 1 ATOM 1276 C CA . ASN A 1 173 ? -42.626 -7.833 34.532 1.00 78.34 ? 358 ASN A CA 1 ATOM 1277 C C . ASN A 1 173 ? -41.818 -8.635 35.543 1.00 76.86 ? 358 ASN A C 1 ATOM 1278 O O . ASN A 1 173 ? -41.630 -9.839 35.392 1.00 76.58 ? 358 ASN A O 1 ATOM 1279 C CB . ASN A 1 173 ? -43.987 -7.429 35.122 1.00 79.74 ? 358 ASN A CB 1 ATOM 1280 C CG . ASN A 1 173 ? -44.971 -8.587 35.225 1.00 80.93 ? 358 ASN A CG 1 ATOM 1281 O OD1 . ASN A 1 173 ? -44.664 -9.729 34.879 1.00 81.42 ? 358 ASN A OD1 1 ATOM 1282 N ND2 . ASN A 1 173 ? -46.185 -8.274 35.715 1.00 81.96 ? 358 ASN A ND2 1 ATOM 1283 N N . GLN A 1 174 ? -41.331 -7.937 36.565 1.00 76.10 ? 359 GLN A N 1 ATOM 1284 C CA . GLN A 1 174 ? -40.537 -8.539 37.629 1.00 76.27 ? 359 GLN A CA 1 ATOM 1285 C C . GLN A 1 174 ? -40.973 -7.949 38.968 1.00 76.05 ? 359 GLN A C 1 ATOM 1286 O O . GLN A 1 174 ? -41.444 -6.816 39.024 1.00 76.12 ? 359 GLN A O 1 ATOM 1287 C CB . GLN A 1 174 ? -39.050 -8.272 37.386 1.00 75.90 ? 359 GLN A CB 1 ATOM 1288 C CG . GLN A 1 174 ? -38.102 -8.999 38.333 1.00 75.79 ? 359 GLN A CG 1 ATOM 1289 C CD . GLN A 1 174 ? -38.093 -10.498 38.117 1.00 74.61 ? 359 GLN A CD 1 ATOM 1290 O OE1 . GLN A 1 174 ? -38.639 -11.257 38.919 1.00 73.69 ? 359 GLN A OE1 1 ATOM 1291 N NE2 . GLN A 1 174 ? -37.477 -10.933 37.023 1.00 74.23 ? 359 GLN A NE2 1 ATOM 1292 N N . THR A 1 175 ? -40.822 -8.727 40.038 1.00 75.78 ? 360 THR A N 1 ATOM 1293 C CA . THR A 1 175 ? -41.255 -8.311 41.370 1.00 75.27 ? 360 THR A CA 1 ATOM 1294 C C . THR A 1 175 ? -40.227 -8.718 42.428 1.00 75.00 ? 360 THR A C 1 ATOM 1295 O O . THR A 1 175 ? -39.740 -9.849 42.419 1.00 75.23 ? 360 THR A O 1 ATOM 1296 C CB . THR A 1 175 ? -42.609 -8.953 41.730 1.00 75.94 ? 360 THR A CB 1 ATOM 1297 O OG1 . THR A 1 175 ? -43.558 -8.697 40.687 1.00 76.52 ? 360 THR A OG1 1 ATOM 1298 C CG2 . THR A 1 175 ? -43.141 -8.400 43.045 1.00 76.07 ? 360 THR A CG2 1 ATOM 1299 N N A ARG A 1 176 ? -39.909 -7.791 43.332 0.50 74.70 ? 361 ARG A N 1 ATOM 1300 N N B ARG A 1 176 ? -39.897 -7.789 43.324 0.50 74.81 ? 361 ARG A N 1 ATOM 1301 C CA A ARG A 1 176 ? -38.979 -8.050 44.434 0.50 74.49 ? 361 ARG A CA 1 ATOM 1302 C CA B ARG A 1 176 ? -38.996 -8.072 44.444 0.50 74.72 ? 361 ARG A CA 1 ATOM 1303 C C A ARG A 1 176 ? -39.480 -7.397 45.724 0.50 73.89 ? 361 ARG A C 1 ATOM 1304 C C B ARG A 1 176 ? -39.487 -7.402 45.723 0.50 74.01 ? 361 ARG A C 1 ATOM 1305 O O A ARG A 1 176 ? -39.853 -6.223 45.724 0.50 73.43 ? 361 ARG A O 1 ATOM 1306 O O B ARG A 1 176 ? -39.857 -6.227 45.717 0.50 73.56 ? 361 ARG A O 1 ATOM 1307 C CB A ARG A 1 176 ? -37.586 -7.512 44.093 0.50 74.17 ? 361 ARG A CB 1 ATOM 1308 C CB B ARG A 1 176 ? -37.574 -7.606 44.127 0.50 74.88 ? 361 ARG A CB 1 ATOM 1309 C CG A ARG A 1 176 ? -36.869 -8.260 42.972 0.50 74.12 ? 361 ARG A CG 1 ATOM 1310 C CG B ARG A 1 176 ? -36.763 -8.604 43.318 0.50 75.02 ? 361 ARG A CG 1 ATOM 1311 C CD A ARG A 1 176 ? -36.322 -9.605 43.438 0.50 73.81 ? 361 ARG A CD 1 ATOM 1312 C CD B ARG A 1 176 ? -35.307 -8.180 43.212 0.50 74.89 ? 361 ARG A CD 1 ATOM 1313 N NE A ARG A 1 176 ? -35.532 -10.263 42.393 0.50 73.87 ? 361 ARG A NE 1 ATOM 1314 N NE B ARG A 1 176 ? -34.569 -8.380 44.459 0.50 74.74 ? 361 ARG A NE 1 ATOM 1315 C CZ A ARG A 1 176 ? -35.978 -11.213 41.568 0.50 73.28 ? 361 ARG A CZ 1 ATOM 1316 C CZ B ARG A 1 176 ? -33.274 -8.114 44.622 0.50 74.69 ? 361 ARG A CZ 1 ATOM 1317 N NH1 A ARG A 1 176 ? -35.158 -11.730 40.660 0.50 73.34 ? 361 ARG A NH1 1 ATOM 1318 N NH1 B ARG A 1 176 ? -32.697 -8.332 45.799 0.50 74.80 ? 361 ARG A NH1 1 ATOM 1319 N NH2 A ARG A 1 176 ? -37.230 -11.656 41.637 0.50 73.04 ? 361 ARG A NH2 1 ATOM 1320 N NH2 B ARG A 1 176 ? -32.548 -7.632 43.618 0.50 74.83 ? 361 ARG A NH2 1 ATOM 1321 N N . GLU A 1 177 ? -39.483 -8.160 46.816 1.00 73.99 ? 362 GLU A N 1 ATOM 1322 C CA . GLU A 1 177 ? -39.925 -7.652 48.119 1.00 74.39 ? 362 GLU A CA 1 ATOM 1323 C C . GLU A 1 177 ? -38.776 -6.997 48.881 1.00 73.43 ? 362 GLU A C 1 ATOM 1324 O O . GLU A 1 177 ? -37.633 -7.450 48.809 1.00 72.98 ? 362 GLU A O 1 ATOM 1325 C CB . GLU A 1 177 ? -40.520 -8.778 48.971 1.00 75.11 ? 362 GLU A CB 1 ATOM 1326 C CG . GLU A 1 177 ? -41.839 -9.340 48.442 1.00 75.28 ? 362 GLU A CG 1 ATOM 1327 C CD . GLU A 1 177 ? -42.590 -10.172 49.478 0.50 74.60 ? 362 GLU A CD 1 ATOM 1328 O OE1 . GLU A 1 177 ? -41.965 -10.626 50.461 0.50 74.28 ? 362 GLU A OE1 1 ATOM 1329 O OE2 . GLU A 1 177 ? -43.810 -10.371 49.306 0.50 74.40 ? 362 GLU A OE2 1 ATOM 1330 N N . LEU A 1 178 ? -39.093 -5.930 49.610 1.00 73.12 ? 363 LEU A N 1 ATOM 1331 C CA . LEU A 1 178 ? -38.146 -5.311 50.531 1.00 73.17 ? 363 LEU A CA 1 ATOM 1332 C C . LEU A 1 178 ? -38.343 -5.886 51.929 1.00 72.43 ? 363 LEU A C 1 ATOM 1333 O O . LEU A 1 178 ? -39.474 -6.086 52.371 1.00 72.12 ? 363 LEU A O 1 ATOM 1334 C CB . LEU A 1 178 ? -38.344 -3.795 50.567 1.00 72.88 ? 363 LEU A CB 1 ATOM 1335 C CG . LEU A 1 178 ? -37.399 -3.011 51.479 1.00 72.79 ? 363 LEU A CG 1 ATOM 1336 C CD1 . LEU A 1 178 ? -35.949 -3.237 51.078 1.00 72.51 ? 363 LEU A CD1 1 ATOM 1337 C CD2 . LEU A 1 178 ? -37.742 -1.532 51.446 1.00 73.09 ? 363 LEU A CD2 1 ATOM 1338 N N . ARG A 1 179 ? -37.238 -6.160 52.613 1.00 72.52 ? 364 ARG A N 1 ATOM 1339 C CA . ARG A 1 179 ? -37.279 -6.555 54.013 1.00 73.17 ? 364 ARG A CA 1 ATOM 1340 C C . ARG A 1 179 ? -36.841 -5.371 54.863 1.00 72.38 ? 364 ARG A C 1 ATOM 1341 O O . ARG A 1 179 ? -35.806 -4.760 54.598 1.00 71.40 ? 364 ARG A O 1 ATOM 1342 C CB . ARG A 1 179 ? -36.379 -7.763 54.262 1.00 73.76 ? 364 ARG A CB 1 ATOM 1343 C CG . ARG A 1 179 ? -36.895 -9.042 53.619 1.00 74.62 ? 364 ARG A CG 1 ATOM 1344 C CD . ARG A 1 179 ? -36.275 -10.291 54.245 1.00 75.26 ? 364 ARG A CD 1 ATOM 1345 N NE . ARG A 1 179 ? -34.829 -10.368 54.036 1.00 75.97 ? 364 ARG A NE 1 ATOM 1346 C CZ . ARG A 1 179 ? -34.242 -10.699 52.885 1.00 76.39 ? 364 ARG A CZ 1 ATOM 1347 N NH1 . ARG A 1 179 ? -34.964 -10.990 51.803 1.00 76.47 ? 364 ARG A NH1 1 ATOM 1348 N NH2 . ARG A 1 179 ? -32.915 -10.736 52.814 1.00 76.18 ? 364 ARG A NH2 1 ATOM 1349 N N . VAL A 1 180 ? -37.647 -5.038 55.869 1.00 72.46 ? 365 VAL A N 1 ATOM 1350 C CA . VAL A 1 180 ? -37.373 -3.902 56.743 1.00 72.25 ? 365 VAL A CA 1 ATOM 1351 C C . VAL A 1 180 ? -37.438 -4.333 58.202 1.00 71.73 ? 365 VAL A C 1 ATOM 1352 O O . VAL A 1 180 ? -38.502 -4.696 58.702 1.00 71.24 ? 365 VAL A O 1 ATOM 1353 C CB . VAL A 1 180 ? -38.378 -2.756 56.511 1.00 71.86 ? 365 VAL A CB 1 ATOM 1354 C CG1 . VAL A 1 180 ? -38.098 -1.597 57.462 1.00 71.34 ? 365 VAL A CG1 1 ATOM 1355 C CG2 . VAL A 1 180 ? -38.325 -2.290 55.066 1.00 71.73 ? 365 VAL A CG2 1 ATOM 1356 N N . LEU A 1 181 ? -36.292 -4.300 58.876 1.00 71.95 ? 366 LEU A N 1 ATOM 1357 C CA . LEU A 1 181 ? -36.237 -4.553 60.309 1.00 71.99 ? 366 LEU A CA 1 ATOM 1358 C C . LEU A 1 181 ? -36.605 -3.261 61.030 1.00 71.49 ? 366 LEU A C 1 ATOM 1359 O O . LEU A 1 181 ? -36.145 -2.184 60.653 1.00 70.84 ? 366 LEU A O 1 ATOM 1360 C CB . LEU A 1 181 ? -34.838 -5.018 60.729 1.00 71.27 ? 366 LEU A CB 1 ATOM 1361 C CG . LEU A 1 181 ? -34.245 -6.206 59.961 1.00 71.03 ? 366 LEU A CG 1 ATOM 1362 C CD1 . LEU A 1 181 ? -32.889 -6.582 60.534 1.00 70.96 ? 366 LEU A CD1 1 ATOM 1363 C CD2 . LEU A 1 181 ? -35.180 -7.407 59.979 1.00 70.94 ? 366 LEU A CD2 1 ATOM 1364 N N . TYR A 1 182 ? -37.456 -3.370 62.047 1.00 72.17 ? 367 TYR A N 1 ATOM 1365 C CA . TYR A 1 182 ? -37.859 -2.209 62.837 1.00 73.31 ? 367 TYR A CA 1 ATOM 1366 C C . TYR A 1 182 ? -37.917 -2.563 64.315 1.00 74.25 ? 367 TYR A C 1 ATOM 1367 O O . TYR A 1 182 ? -38.418 -3.626 64.691 1.00 73.16 ? 367 TYR A O 1 ATOM 1368 C CB . TYR A 1 182 ? -39.203 -1.643 62.357 1.00 72.95 ? 367 TYR A CB 1 ATOM 1369 C CG . TYR A 1 182 ? -40.321 -2.657 62.225 1.00 72.90 ? 367 TYR A CG 1 ATOM 1370 C CD1 . TYR A 1 182 ? -40.448 -3.432 61.079 1.00 72.73 ? 367 TYR A CD1 1 ATOM 1371 C CD2 . TYR A 1 182 ? -41.265 -2.821 63.235 1.00 73.16 ? 367 TYR A CD2 1 ATOM 1372 C CE1 . TYR A 1 182 ? -41.474 -4.354 60.944 1.00 72.73 ? 367 TYR A CE1 1 ATOM 1373 C CE2 . TYR A 1 182 ? -42.300 -3.742 63.107 1.00 73.06 ? 367 TYR A CE2 1 ATOM 1374 C CZ . TYR A 1 182 ? -42.394 -4.505 61.960 1.00 72.76 ? 367 TYR A CZ 1 ATOM 1375 O OH . TYR A 1 182 ? -43.409 -5.417 61.824 1.00 72.77 ? 367 TYR A OH 1 ATOM 1376 N N . GLY A 1 183 ? -37.399 -1.654 65.142 1.00 75.83 ? 368 GLY A N 1 ATOM 1377 C CA . GLY A 1 183 ? -37.186 -1.905 66.566 1.00 75.24 ? 368 GLY A CA 1 ATOM 1378 C C . GLY A 1 183 ? -38.447 -2.295 67.296 1.00 75.50 ? 368 GLY A C 1 ATOM 1379 O O . GLY A 1 183 ? -39.539 -2.189 66.742 1.00 76.26 ? 368 GLY A O 1 ATOM 1380 N N . PRO A 1 184 ? -38.309 -2.746 68.554 1.00 75.66 ? 369 PRO A N 1 ATOM 1381 C CA . PRO A 1 184 ? -39.487 -3.186 69.298 1.00 75.93 ? 369 PRO A CA 1 ATOM 1382 C C . PRO A 1 184 ? -40.473 -2.045 69.532 1.00 76.09 ? 369 PRO A C 1 ATOM 1383 O O . PRO A 1 184 ? -40.071 -0.883 69.591 1.00 76.44 ? 369 PRO A O 1 ATOM 1384 C CB . PRO A 1 184 ? -38.907 -3.677 70.633 1.00 75.92 ? 369 PRO A CB 1 ATOM 1385 C CG . PRO A 1 184 ? -37.445 -3.848 70.399 1.00 75.80 ? 369 PRO A CG 1 ATOM 1386 C CD . PRO A 1 184 ? -37.078 -2.859 69.354 1.00 75.70 ? 369 PRO A CD 1 ATOM 1387 N N . ARG A 1 185 ? -41.754 -2.380 69.635 1.00 76.51 ? 370 ARG A N 1 ATOM 1388 C CA . ARG A 1 185 ? -42.777 -1.414 70.021 1.00 76.92 ? 370 ARG A CA 1 ATOM 1389 C C . ARG A 1 185 ? -43.779 -2.063 70.956 1.00 76.21 ? 370 ARG A C 1 ATOM 1390 O O . ARG A 1 185 ? -44.239 -3.175 70.703 1.00 75.88 ? 370 ARG A O 1 ATOM 1391 C CB . ARG A 1 185 ? -43.506 -0.857 68.793 1.00 78.38 ? 370 ARG A CB 1 ATOM 1392 C CG . ARG A 1 185 ? -42.912 0.438 68.244 1.00 79.17 ? 370 ARG A CG 1 ATOM 1393 C CD . ARG A 1 185 ? -43.941 1.231 67.433 1.00 79.22 ? 370 ARG A CD 1 ATOM 1394 N NE . ARG A 1 185 ? -43.439 2.550 67.035 1.00 79.63 ? 370 ARG A NE 1 ATOM 1395 C CZ . ARG A 1 185 ? -43.361 3.616 67.839 1.00 80.47 ? 370 ARG A CZ 1 ATOM 1396 N NH1 . ARG A 1 185 ? -43.747 3.548 69.113 1.00 80.52 ? 370 ARG A NH1 1 ATOM 1397 N NH2 . ARG A 1 185 ? -42.887 4.765 67.366 1.00 80.22 ? 370 ARG A NH2 1 ATOM 1398 N N . LEU A 1 186 ? -44.093 -1.368 72.047 1.00 76.15 ? 371 LEU A N 1 ATOM 1399 C CA . LEU A 1 186 ? -45.199 -1.742 72.918 1.00 75.71 ? 371 LEU A CA 1 ATOM 1400 C C . LEU A 1 186 ? -46.350 -0.770 72.682 1.00 75.32 ? 371 LEU A C 1 ATOM 1401 O O . LEU A 1 186 ? -46.524 0.203 73.417 1.00 74.69 ? 371 LEU A O 1 ATOM 1402 C CB . LEU A 1 186 ? -44.765 -1.722 74.386 1.00 74.41 ? 371 LEU A CB 1 ATOM 1403 C CG . LEU A 1 186 ? -43.804 -2.833 74.810 1.00 73.28 ? 371 LEU A CG 1 ATOM 1404 C CD1 . LEU A 1 186 ? -43.280 -2.570 76.209 1.00 73.54 ? 371 LEU A CD1 1 ATOM 1405 C CD2 . LEU A 1 186 ? -44.475 -4.195 74.737 1.00 72.57 ? 371 LEU A CD2 1 ATOM 1406 N N . ASP A 1 187 ? -47.123 -1.040 71.635 1.00 75.91 ? 372 ASP A N 1 ATOM 1407 C CA . ASP A 1 187 ? -48.262 -0.206 71.271 1.00 76.00 ? 372 ASP A CA 1 ATOM 1408 C C . ASP A 1 187 ? -49.397 -0.396 72.270 1.00 75.60 ? 372 ASP A C 1 ATOM 1409 O O . ASP A 1 187 ? -49.643 -1.511 72.736 1.00 74.86 ? 372 ASP A O 1 ATOM 1410 C CB . ASP A 1 187 ? -48.740 -0.558 69.861 1.00 76.82 ? 372 ASP A CB 1 ATOM 1411 C CG . ASP A 1 187 ? -49.764 0.424 69.328 1.00 77.25 ? 372 ASP A CG 1 ATOM 1412 O OD1 . ASP A 1 187 ? -49.471 1.103 68.323 1.00 78.31 ? 372 ASP A OD1 1 ATOM 1413 O OD2 . ASP A 1 187 ? -50.859 0.517 69.911 1.00 77.85 ? 372 ASP A OD2 1 ATOM 1414 N N . GLU A 1 188 ? -50.092 0.695 72.581 1.00 76.15 ? 373 GLU A N 1 ATOM 1415 C CA . GLU A 1 188 ? -51.158 0.671 73.581 1.00 76.62 ? 373 GLU A CA 1 ATOM 1416 C C . GLU A 1 188 ? -52.284 -0.295 73.218 1.00 76.79 ? 373 GLU A C 1 ATOM 1417 O O . GLU A 1 188 ? -52.812 -0.976 74.096 1.00 77.39 ? 373 GLU A O 1 ATOM 1418 C CB . GLU A 1 188 ? -51.737 2.074 73.797 1.00 76.65 ? 373 GLU A CB 1 ATOM 1419 C CG . GLU A 1 188 ? -52.700 2.166 74.984 1.00 76.47 ? 373 GLU A CG 1 ATOM 1420 C CD . GLU A 1 188 ? -53.204 3.577 75.236 1.00 77.02 ? 373 GLU A CD 1 ATOM 1421 O OE1 . GLU A 1 188 ? -53.438 3.925 76.416 1.00 77.76 ? 373 GLU A OE1 1 ATOM 1422 O OE2 . GLU A 1 188 ? -53.371 4.338 74.260 1.00 76.82 ? 373 GLU A OE2 1 ATOM 1423 N N . ARG A 1 189 ? -52.646 -0.358 71.935 1.00 76.29 ? 374 ARG A N 1 ATOM 1424 C CA . ARG A 1 189 ? -53.780 -1.183 71.500 1.00 76.95 ? 374 ARG A CA 1 ATOM 1425 C C . ARG A 1 189 ? -53.573 -2.675 71.767 1.00 77.61 ? 374 ARG A C 1 ATOM 1426 O O . ARG A 1 189 ? -54.535 -3.396 72.027 1.00 78.15 ? 374 ARG A O 1 ATOM 1427 C CB . ARG A 1 189 ? -54.105 -0.958 70.016 1.00 76.23 ? 374 ARG A CB 1 ATOM 1428 C CG . ARG A 1 189 ? -54.781 0.382 69.716 1.00 76.01 ? 374 ARG A CG 1 ATOM 1429 C CD . ARG A 1 189 ? -53.852 1.340 68.989 1.00 76.22 ? 374 ARG A CD 1 ATOM 1430 N NE . ARG A 1 189 ? -53.860 1.118 67.542 1.00 76.07 ? 374 ARG A NE 1 ATOM 1431 C CZ . ARG A 1 189 ? -52.868 1.443 66.712 1.00 76.10 ? 374 ARG A CZ 1 ATOM 1432 N NH1 . ARG A 1 189 ? -51.756 2.008 67.165 1.00 75.87 ? 374 ARG A NH1 1 ATOM 1433 N NH2 . ARG A 1 189 ? -52.987 1.193 65.414 1.00 76.50 ? 374 ARG A NH2 1 ATOM 1434 N N . ASP A 1 190 ? -52.328 -3.137 71.705 1.00 77.81 ? 375 ASP A N 1 ATOM 1435 C CA . ASP A 1 190 ? -52.016 -4.531 72.027 1.00 78.38 ? 375 ASP A CA 1 ATOM 1436 C C . ASP A 1 190 ? -51.317 -4.688 73.381 1.00 78.71 ? 375 ASP A C 1 ATOM 1437 O O . ASP A 1 190 ? -50.960 -5.799 73.765 1.00 79.36 ? 375 ASP A O 1 ATOM 1438 C CB . ASP A 1 190 ? -51.175 -5.158 70.912 1.00 80.15 ? 375 ASP A CB 1 ATOM 1439 C CG . ASP A 1 190 ? -51.992 -5.464 69.673 1.00 82.29 ? 375 ASP A CG 1 ATOM 1440 O OD1 . ASP A 1 190 ? -51.458 -6.114 68.749 1.00 83.01 ? 375 ASP A OD1 1 ATOM 1441 O OD2 . ASP A 1 190 ? -53.178 -5.065 69.625 1.00 83.16 ? 375 ASP A OD2 1 ATOM 1442 N N . CYS A 1 191 ? -51.138 -3.585 74.104 1.00 78.57 ? 376 CYS A N 1 ATOM 1443 C CA . CYS A 1 191 ? -50.558 -3.633 75.444 1.00 78.06 ? 376 CYS A CA 1 ATOM 1444 C C . CYS A 1 191 ? -50.947 -2.388 76.251 1.00 77.09 ? 376 CYS A C 1 ATOM 1445 O O . CYS A 1 191 ? -50.156 -1.452 76.376 1.00 77.20 ? 376 CYS A O 1 ATOM 1446 C CB . CYS A 1 191 ? -49.034 -3.770 75.359 1.00 79.17 ? 376 CYS A CB 1 ATOM 1447 S SG . CYS A 1 191 ? -48.220 -4.002 76.957 1.00 80.15 ? 376 CYS A SG 1 ATOM 1448 N N . PRO A 1 192 ? -52.175 -2.375 76.801 1.00 76.63 ? 377 PRO A N 1 ATOM 1449 C CA . PRO A 1 192 ? -52.628 -1.212 77.566 1.00 76.91 ? 377 PRO A CA 1 ATOM 1450 C C . PRO A 1 192 ? -51.897 -1.079 78.905 1.00 76.39 ? 377 PRO A C 1 ATOM 1451 O O . PRO A 1 192 ? -51.435 -2.078 79.464 1.00 75.55 ? 377 PRO A O 1 ATOM 1452 C CB . PRO A 1 192 ? -54.118 -1.489 77.776 1.00 76.35 ? 377 PRO A CB 1 ATOM 1453 C CG . PRO A 1 192 ? -54.234 -2.961 77.732 1.00 76.31 ? 377 PRO A CG 1 ATOM 1454 C CD . PRO A 1 192 ? -53.199 -3.435 76.756 1.00 76.34 ? 377 PRO A CD 1 ATOM 1455 N N . GLY A 1 193 ? -51.798 0.151 79.402 1.00 76.63 ? 378 GLY A N 1 ATOM 1456 C CA . GLY A 1 193 ? -51.001 0.446 80.589 1.00 77.16 ? 378 GLY A CA 1 ATOM 1457 C C . GLY A 1 193 ? -51.772 0.528 81.895 1.00 77.11 ? 378 GLY A C 1 ATOM 1458 O O . GLY A 1 193 ? -51.211 0.932 82.914 1.00 76.88 ? 378 GLY A O 1 ATOM 1459 N N . ASN A 1 194 ? -53.046 0.141 81.881 1.00 77.71 ? 379 ASN A N 1 ATOM 1460 C CA . ASN A 1 194 ? -53.881 0.246 83.077 1.00 77.53 ? 379 ASN A CA 1 ATOM 1461 C C . ASN A 1 194 ? -54.977 -0.819 83.138 1.00 77.58 ? 379 ASN A C 1 ATOM 1462 O O . ASN A 1 194 ? -55.848 -0.881 82.265 1.00 78.33 ? 379 ASN A O 1 ATOM 1463 C CB . ASN A 1 194 ? -54.507 1.642 83.160 1.00 78.41 ? 379 ASN A CB 1 ATOM 1464 C CG . ASN A 1 194 ? -55.063 1.952 84.538 1.00 79.32 ? 379 ASN A CG 1 ATOM 1465 O OD1 . ASN A 1 194 ? -54.387 1.765 85.552 1.00 80.42 ? 379 ASN A OD1 1 ATOM 1466 N ND2 . ASN A 1 194 ? -56.300 2.438 84.581 1.00 80.19 ? 379 ASN A ND2 1 ATOM 1467 N N . TRP A 1 195 ? -54.919 -1.653 84.176 1.00 76.61 ? 380 TRP A N 1 ATOM 1468 C CA . TRP A 1 195 ? -55.946 -2.658 84.437 1.00 76.17 ? 380 TRP A CA 1 ATOM 1469 C C . TRP A 1 195 ? -56.634 -2.370 85.766 1.00 75.79 ? 380 TRP A C 1 ATOM 1470 O O . TRP A 1 195 ? -56.024 -1.823 86.687 1.00 76.02 ? 380 TRP A O 1 ATOM 1471 C CB . TRP A 1 195 ? -55.332 -4.055 84.498 1.00 75.94 ? 380 TRP A CB 1 ATOM 1472 C CG . TRP A 1 195 ? -54.647 -4.497 83.245 1.00 75.90 ? 380 TRP A CG 1 ATOM 1473 C CD1 . TRP A 1 195 ? -53.302 -4.613 83.044 1.00 75.96 ? 380 TRP A CD1 1 ATOM 1474 C CD2 . TRP A 1 195 ? -55.271 -4.909 82.025 1.00 75.71 ? 380 TRP A CD2 1 ATOM 1475 N NE1 . TRP A 1 195 ? -53.048 -5.065 81.773 1.00 75.87 ? 380 TRP A NE1 1 ATOM 1476 C CE2 . TRP A 1 195 ? -54.240 -5.255 81.125 1.00 75.81 ? 380 TRP A CE2 1 ATOM 1477 C CE3 . TRP A 1 195 ? -56.601 -5.017 81.603 1.00 75.69 ? 380 TRP A CE3 1 ATOM 1478 C CZ2 . TRP A 1 195 ? -54.496 -5.700 79.829 1.00 75.86 ? 380 TRP A CZ2 1 ATOM 1479 C CZ3 . TRP A 1 195 ? -56.854 -5.459 80.313 1.00 75.86 ? 380 TRP A CZ3 1 ATOM 1480 C CH2 . TRP A 1 195 ? -55.806 -5.795 79.442 1.00 75.97 ? 380 TRP A CH2 1 ATOM 1481 N N . THR A 1 196 ? -57.905 -2.745 85.858 1.00 75.02 ? 381 THR A N 1 ATOM 1482 C CA . THR A 1 196 ? -58.642 -2.692 87.115 1.00 74.78 ? 381 THR A CA 1 ATOM 1483 C C . THR A 1 196 ? -59.515 -3.937 87.229 1.00 74.18 ? 381 THR A C 1 ATOM 1484 O O . THR A 1 196 ? -60.515 -4.065 86.525 1.00 73.87 ? 381 THR A O 1 ATOM 1485 C CB . THR A 1 196 ? -59.517 -1.429 87.211 1.00 74.70 ? 381 THR A CB 1 ATOM 1486 O OG1 . THR A 1 196 ? -58.688 -0.264 87.129 1.00 74.59 ? 381 THR A OG1 1 ATOM 1487 C CG2 . THR A 1 196 ? -60.283 -1.407 88.526 1.00 74.77 ? 381 THR A CG2 1 ATOM 1488 N N . TRP A 1 197 ? -59.118 -4.856 88.107 1.00 74.15 ? 382 TRP A N 1 ATOM 1489 C CA . TRP A 1 197 ? -59.818 -6.127 88.271 1.00 73.83 ? 382 TRP A CA 1 ATOM 1490 C C . TRP A 1 197 ? -60.370 -6.279 89.681 1.00 72.82 ? 382 TRP A C 1 ATOM 1491 O O . TRP A 1 197 ? -59.766 -5.794 90.636 1.00 72.44 ? 382 TRP A O 1 ATOM 1492 C CB . TRP A 1 197 ? -58.875 -7.294 87.990 1.00 74.78 ? 382 TRP A CB 1 ATOM 1493 C CG . TRP A 1 197 ? -58.367 -7.336 86.596 1.00 74.82 ? 382 TRP A CG 1 ATOM 1494 C CD1 . TRP A 1 197 ? -59.086 -7.140 85.453 1.00 74.96 ? 382 TRP A CD1 1 ATOM 1495 C CD2 . TRP A 1 197 ? -57.032 -7.632 86.185 1.00 74.50 ? 382 TRP A CD2 1 ATOM 1496 N NE1 . TRP A 1 197 ? -58.275 -7.277 84.356 1.00 75.00 ? 382 TRP A NE1 1 ATOM 1497 C CE2 . TRP A 1 197 ? -57.007 -7.580 84.778 1.00 74.80 ? 382 TRP A CE2 1 ATOM 1498 C CE3 . TRP A 1 197 ? -55.851 -7.929 86.871 1.00 74.79 ? 382 TRP A CE3 1 ATOM 1499 C CZ2 . TRP A 1 197 ? -55.847 -7.812 84.042 1.00 74.89 ? 382 TRP A CZ2 1 ATOM 1500 C CZ3 . TRP A 1 197 ? -54.697 -8.160 86.141 1.00 74.89 ? 382 TRP A CZ3 1 ATOM 1501 C CH2 . TRP A 1 197 ? -54.704 -8.099 84.741 1.00 74.95 ? 382 TRP A CH2 1 ATOM 1502 N N . PRO A 1 198 ? -61.520 -6.965 89.820 1.00 72.12 ? 383 PRO A N 1 ATOM 1503 C CA . PRO A 1 198 ? -61.990 -7.332 91.149 1.00 72.16 ? 383 PRO A CA 1 ATOM 1504 C C . PRO A 1 198 ? -61.145 -8.451 91.751 1.00 71.06 ? 383 PRO A C 1 ATOM 1505 O O . PRO A 1 198 ? -60.666 -9.325 91.027 1.00 69.96 ? 383 PRO A O 1 ATOM 1506 C CB . PRO A 1 198 ? -63.428 -7.821 90.902 1.00 72.29 ? 383 PRO A CB 1 ATOM 1507 C CG . PRO A 1 198 ? -63.741 -7.491 89.479 1.00 72.12 ? 383 PRO A CG 1 ATOM 1508 C CD . PRO A 1 198 ? -62.446 -7.418 88.770 1.00 72.01 ? 383 PRO A CD 1 ATOM 1509 N N . GLU A 1 199 ? -60.975 -8.419 93.069 1.00 71.57 ? 384 GLU A N 1 ATOM 1510 C CA . GLU A 1 199 ? -60.213 -9.442 93.778 1.00 72.07 ? 384 GLU A CA 1 ATOM 1511 C C . GLU A 1 199 ? -60.904 -10.799 93.641 1.00 71.98 ? 384 GLU A C 1 ATOM 1512 O O . GLU A 1 199 ? -62.128 -10.871 93.559 1.00 72.36 ? 384 GLU A O 1 ATOM 1513 C CB . GLU A 1 199 ? -60.065 -9.061 95.256 1.00 71.93 ? 384 GLU A CB 1 ATOM 1514 C CG . GLU A 1 199 ? -58.981 -9.827 96.005 1.00 72.00 ? 384 GLU A CG 1 ATOM 1515 C CD . GLU A 1 199 ? -58.838 -9.383 97.457 1.00 72.88 ? 384 GLU A CD 1 ATOM 1516 O OE1 . GLU A 1 199 ? -59.289 -8.267 97.795 1.00 73.66 ? 384 GLU A OE1 1 ATOM 1517 O OE2 . GLU A 1 199 ? -58.270 -10.151 98.263 1.00 73.24 ? 384 GLU A OE2 1 ATOM 1518 N N . ASN A 1 200 ? -60.106 -11.865 93.597 1.00 72.16 ? 385 ASN A N 1 ATOM 1519 C CA . ASN A 1 200 ? -60.608 -13.241 93.470 1.00 72.29 ? 385 ASN A CA 1 ATOM 1520 C C . ASN A 1 200 ? -61.379 -13.522 92.170 1.00 72.32 ? 385 ASN A C 1 ATOM 1521 O O . ASN A 1 200 ? -62.230 -14.413 92.132 1.00 72.52 ? 385 ASN A O 1 ATOM 1522 C CB . ASN A 1 200 ? -61.477 -13.619 94.683 1.00 72.56 ? 385 ASN A CB 1 ATOM 1523 C CG . ASN A 1 200 ? -60.725 -13.526 95.999 1.00 72.84 ? 385 ASN A CG 1 ATOM 1524 O OD1 . ASN A 1 200 ? -59.546 -13.871 96.082 1.00 73.10 ? 385 ASN A OD1 1 ATOM 1525 N ND2 . ASN A 1 200 ? -61.413 -13.070 97.041 1.00 72.73 ? 385 ASN A ND2 1 ATOM 1526 N N . SER A 1 201 ? -61.071 -12.775 91.109 1.00 72.36 ? 386 SER A N 1 ATOM 1527 C CA . SER A 1 201 ? -61.700 -12.985 89.800 1.00 72.26 ? 386 SER A CA 1 ATOM 1528 C C . SER A 1 201 ? -60.699 -13.575 88.814 1.00 72.11 ? 386 SER A C 1 ATOM 1529 O O . SER A 1 201 ? -59.487 -13.420 88.981 1.00 71.88 ? 386 SER A O 1 ATOM 1530 C CB . SER A 1 201 ? -62.261 -11.668 89.249 1.00 71.53 ? 386 SER A CB 1 ATOM 1531 O OG . SER A 1 201 ? -61.227 -10.798 88.813 1.00 70.85 ? 386 SER A OG 1 ATOM 1532 N N . GLN A 1 202 ? -61.213 -14.253 87.791 1.00 72.31 ? 387 GLN A N 1 ATOM 1533 C CA . GLN A 1 202 ? -60.373 -14.817 86.735 1.00 72.73 ? 387 GLN A CA 1 ATOM 1534 C C . GLN A 1 202 ? -60.144 -13.780 85.650 1.00 72.33 ? 387 GLN A C 1 ATOM 1535 O O . GLN A 1 202 ? -61.099 -13.271 85.066 1.00 72.54 ? 387 GLN A O 1 ATOM 1536 C CB . GLN A 1 202 ? -61.020 -16.066 86.132 1.00 74.32 ? 387 GLN A CB 1 ATOM 1537 C CG . GLN A 1 202 ? -60.930 -17.303 87.018 1.00 76.12 ? 387 GLN A CG 1 ATOM 1538 C CD . GLN A 1 202 ? -59.495 -17.742 87.284 1.00 77.69 ? 387 GLN A CD 1 ATOM 1539 O OE1 . GLN A 1 202 ? -59.153 -18.121 88.404 1.00 78.90 ? 387 GLN A OE1 1 ATOM 1540 N NE2 . GLN A 1 202 ? -58.651 -17.687 86.256 1.00 77.34 ? 387 GLN A NE2 1 ATOM 1541 N N . GLN A 1 203 ? -58.876 -13.467 85.390 1.00 72.34 ? 388 GLN A N 1 ATOM 1542 C CA . GLN A 1 203 ? -58.506 -12.466 84.390 1.00 72.83 ? 388 GLN A CA 1 ATOM 1543 C C . GLN A 1 203 ? -57.283 -12.921 83.595 1.00 72.77 ? 388 GLN A C 1 ATOM 1544 O O . GLN A 1 203 ? -56.471 -13.706 84.085 1.00 72.17 ? 388 GLN A O 1 ATOM 1545 C CB . GLN A 1 203 ? -58.202 -11.123 85.062 1.00 72.53 ? 388 GLN A CB 1 ATOM 1546 C CG . GLN A 1 203 ? -59.287 -10.614 86.013 1.00 72.84 ? 388 GLN A CG 1 ATOM 1547 C CD . GLN A 1 203 ? -60.567 -10.209 85.307 1.00 73.34 ? 388 GLN A CD 1 ATOM 1548 O OE1 . GLN A 1 203 ? -60.590 -10.020 84.091 1.00 74.57 ? 388 GLN A OE1 1 ATOM 1549 N NE2 . GLN A 1 203 ? -61.643 -10.072 86.072 1.00 72.65 ? 388 GLN A NE2 1 ATOM 1550 N N . THR A 1 204 ? -57.166 -12.424 82.366 1.00 73.58 ? 389 THR A N 1 ATOM 1551 C CA . THR A 1 204 ? -55.997 -12.674 81.526 1.00 74.22 ? 389 THR A CA 1 ATOM 1552 C C . THR A 1 204 ? -55.356 -11.342 81.152 1.00 74.47 ? 389 THR A C 1 ATOM 1553 O O . THR A 1 204 ? -55.938 -10.572 80.391 1.00 74.14 ? 389 THR A O 1 ATOM 1554 C CB . THR A 1 204 ? -56.373 -13.422 80.227 1.00 73.87 ? 389 THR A CB 1 ATOM 1555 O OG1 . THR A 1 204 ? -57.085 -14.622 80.546 1.00 74.26 ? 389 THR A OG1 1 ATOM 1556 C CG2 . THR A 1 204 ? -55.125 -13.776 79.430 1.00 73.49 ? 389 THR A CG2 1 ATOM 1557 N N . PRO A 1 205 ? -54.159 -11.053 81.696 1.00 75.43 ? 390 PRO A N 1 ATOM 1558 C CA . PRO A 1 205 ? -53.477 -9.833 81.286 1.00 76.50 ? 390 PRO A CA 1 ATOM 1559 C C . PRO A 1 205 ? -52.943 -9.977 79.868 1.00 78.61 ? 390 PRO A C 1 ATOM 1560 O O . PRO A 1 205 ? -52.436 -11.042 79.504 1.00 79.69 ? 390 PRO A O 1 ATOM 1561 C CB . PRO A 1 205 ? -52.332 -9.714 82.293 1.00 75.64 ? 390 PRO A CB 1 ATOM 1562 C CG . PRO A 1 205 ? -52.075 -11.085 82.733 1.00 75.36 ? 390 PRO A CG 1 ATOM 1563 C CD . PRO A 1 205 ? -53.380 -11.810 82.690 1.00 75.11 ? 390 PRO A CD 1 ATOM 1564 N N . MET A 1 206 ? -53.062 -8.912 79.080 1.00 79.01 ? 391 MET A N 1 ATOM 1565 C CA . MET A 1 206 ? -52.750 -8.958 77.656 1.00 78.86 ? 391 MET A CA 1 ATOM 1566 C C . MET A 1 206 ? -51.713 -7.899 77.294 1.00 80.21 ? 391 MET A C 1 ATOM 1567 O O . MET A 1 206 ? -51.848 -6.732 77.666 1.00 80.55 ? 391 MET A O 1 ATOM 1568 C CB . MET A 1 206 ? -54.024 -8.739 76.839 1.00 79.01 ? 391 MET A CB 1 ATOM 1569 C CG . MET A 1 206 ? -55.070 -9.835 77.007 1.00 79.11 ? 391 MET A CG 1 ATOM 1570 S SD . MET A 1 206 ? -54.747 -11.304 76.010 1.00 79.59 ? 391 MET A SD 1 ATOM 1571 C CE . MET A 1 206 ? -55.119 -10.685 74.372 1.00 79.36 ? 391 MET A CE 1 ATOM 1572 N N . CYS A 1 207 ? -50.679 -8.320 76.569 1.00 80.57 ? 392 CYS A N 1 ATOM 1573 C CA . CYS A 1 207 ? -49.622 -7.421 76.110 1.00 79.23 ? 392 CYS A CA 1 ATOM 1574 C C . CYS A 1 207 ? -48.781 -8.117 75.042 1.00 78.59 ? 392 CYS A C 1 ATOM 1575 O O . CYS A 1 207 ? -48.093 -9.093 75.335 1.00 79.00 ? 392 CYS A O 1 ATOM 1576 C CB . CYS A 1 207 ? -48.730 -6.989 77.279 1.00 80.45 ? 392 CYS A CB 1 ATOM 1577 S SG . CYS A 1 207 ? -47.385 -5.853 76.816 1.00 81.17 ? 392 CYS A SG 1 ATOM 1578 N N . GLN A 1 208 ? -48.858 -7.625 73.807 1.00 77.81 ? 393 GLN A N 1 ATOM 1579 C CA . GLN A 1 208 ? -48.038 -8.138 72.709 1.00 77.58 ? 393 GLN A CA 1 ATOM 1580 C C . GLN A 1 208 ? -47.165 -7.028 72.146 1.00 76.81 ? 393 GLN A C 1 ATOM 1581 O O . GLN A 1 208 ? -47.633 -5.909 71.936 1.00 76.35 ? 393 GLN A O 1 ATOM 1582 C CB . GLN A 1 208 ? -48.911 -8.709 71.591 1.00 77.63 ? 393 GLN A CB 1 ATOM 1583 C CG . GLN A 1 208 ? -49.354 -10.146 71.808 1.00 77.65 ? 393 GLN A CG 1 ATOM 1584 C CD . GLN A 1 208 ? -49.751 -10.831 70.514 1.00 77.73 ? 393 GLN A CD 1 ATOM 1585 O OE1 . GLN A 1 208 ? -50.929 -11.078 70.267 1.00 78.94 ? 393 GLN A OE1 1 ATOM 1586 N NE2 . GLN A 1 208 ? -48.768 -11.129 69.676 1.00 76.84 ? 393 GLN A NE2 1 ATOM 1587 N N . ALA A 1 209 ? -45.898 -7.351 71.898 1.00 76.84 ? 394 ALA A N 1 ATOM 1588 C CA . ALA A 1 209 ? -44.940 -6.394 71.353 1.00 76.94 ? 394 ALA A CA 1 ATOM 1589 C C . ALA A 1 209 ? -44.822 -6.571 69.843 1.00 76.16 ? 394 ALA A C 1 ATOM 1590 O O . ALA A 1 209 ? -44.973 -7.682 69.325 1.00 75.05 ? 394 ALA A O 1 ATOM 1591 C CB . ALA A 1 209 ? -43.583 -6.577 72.017 1.00 76.89 ? 394 ALA A CB 1 ATOM 1592 N N . TRP A 1 210 ? -44.569 -5.469 69.140 1.00 76.58 ? 395 TRP A N 1 ATOM 1593 C CA . TRP A 1 210 ? -44.393 -5.498 67.689 1.00 76.99 ? 395 TRP A CA 1 ATOM 1594 C C . TRP A 1 210 ? -42.929 -5.320 67.345 1.00 76.97 ? 395 TRP A C 1 ATOM 1595 O O . TRP A 1 210 ? -42.186 -4.670 68.078 1.00 77.39 ? 395 TRP A O 1 ATOM 1596 C CB . TRP A 1 210 ? -45.201 -4.390 67.010 1.00 76.85 ? 395 TRP A CB 1 ATOM 1597 C CG . TRP A 1 210 ? -46.660 -4.409 67.319 1.00 76.76 ? 395 TRP A CG 1 ATOM 1598 C CD1 . TRP A 1 210 ? -47.370 -5.429 67.879 1.00 76.84 ? 395 TRP A CD1 1 ATOM 1599 C CD2 . TRP A 1 210 ? -47.599 -3.365 67.053 1.00 76.85 ? 395 TRP A CD2 1 ATOM 1600 N NE1 . TRP A 1 210 ? -48.688 -5.078 67.999 1.00 76.88 ? 395 TRP A NE1 1 ATOM 1601 C CE2 . TRP A 1 210 ? -48.859 -3.816 67.496 1.00 76.85 ? 395 TRP A CE2 1 ATOM 1602 C CE3 . TRP A 1 210 ? -47.497 -2.088 66.491 1.00 76.95 ? 395 TRP A CE3 1 ATOM 1603 C CZ2 . TRP A 1 210 ? -50.010 -3.037 67.393 1.00 76.89 ? 395 TRP A CZ2 1 ATOM 1604 C CZ3 . TRP A 1 210 ? -48.642 -1.313 66.388 1.00 76.86 ? 395 TRP A CZ3 1 ATOM 1605 C CH2 . TRP A 1 210 ? -49.882 -1.791 66.836 1.00 76.90 ? 395 TRP A CH2 1 ATOM 1606 N N . GLY A 1 211 ? -42.519 -5.898 66.224 1.00 77.11 ? 396 GLY A N 1 ATOM 1607 C CA . GLY A 1 211 ? -41.149 -5.760 65.763 1.00 77.56 ? 396 GLY A CA 1 ATOM 1608 C C . GLY A 1 211 ? -40.741 -6.830 64.776 1.00 77.74 ? 396 GLY A C 1 ATOM 1609 O O . GLY A 1 211 ? -41.268 -7.943 64.792 1.00 77.25 ? 396 GLY A O 1 ATOM 1610 N N . ASN A 1 212 ? -39.806 -6.470 63.905 1.00 78.97 ? 397 ASN A N 1 ATOM 1611 C CA . ASN A 1 212 ? -39.120 -7.416 63.044 1.00 78.69 ? 397 ASN A CA 1 ATOM 1612 C C . ASN A 1 212 ? -37.635 -7.348 63.396 1.00 78.88 ? 397 ASN A C 1 ATOM 1613 O O . ASN A 1 212 ? -37.002 -6.314 63.177 1.00 78.90 ? 397 ASN A O 1 ATOM 1614 C CB . ASN A 1 212 ? -39.348 -7.055 61.573 1.00 79.21 ? 397 ASN A CB 1 ATOM 1615 C CG . ASN A 1 212 ? -38.738 -8.067 60.614 1.00 79.78 ? 397 ASN A CG 1 ATOM 1616 O OD1 . ASN A 1 212 ? -38.461 -9.209 60.985 1.00 80.48 ? 397 ASN A OD1 1 ATOM 1617 N ND2 . ASN A 1 212 ? -38.532 -7.649 59.371 1.00 79.84 ? 397 ASN A ND2 1 ATOM 1618 N N . PRO A 1 213 ? -37.078 -8.428 63.982 1.00 78.94 ? 398 PRO A N 1 ATOM 1619 C CA . PRO A 1 213 ? -37.725 -9.704 64.308 1.00 79.15 ? 398 PRO A CA 1 ATOM 1620 C C . PRO A 1 213 ? -38.659 -9.610 65.513 1.00 79.57 ? 398 PRO A C 1 ATOM 1621 O O . PRO A 1 213 ? -38.617 -8.625 66.257 1.00 79.27 ? 398 PRO A O 1 ATOM 1622 C CB . PRO A 1 213 ? -36.544 -10.638 64.628 1.00 78.54 ? 398 PRO A CB 1 ATOM 1623 C CG . PRO A 1 213 ? -35.299 -9.855 64.341 1.00 78.56 ? 398 PRO A CG 1 ATOM 1624 C CD . PRO A 1 213 ? -35.668 -8.422 64.400 1.00 78.43 ? 398 PRO A CD 1 ATOM 1625 N N . LEU A 1 214 ? -39.491 -10.636 65.692 1.00 79.91 ? 399 LEU A N 1 ATOM 1626 C CA . LEU A 1 214 ? -40.438 -10.696 66.808 1.00 79.87 ? 399 LEU A CA 1 ATOM 1627 C C . LEU A 1 214 ? -39.726 -10.463 68.134 1.00 79.09 ? 399 LEU A C 1 ATOM 1628 O O . LEU A 1 214 ? -38.834 -11.230 68.492 1.00 78.61 ? 399 LEU A O 1 ATOM 1629 C CB . LEU A 1 214 ? -41.134 -12.058 66.851 1.00 81.08 ? 399 LEU A CB 1 ATOM 1630 C CG . LEU A 1 214 ? -42.160 -12.335 65.755 1.00 81.87 ? 399 LEU A CG 1 ATOM 1631 C CD1 . LEU A 1 214 ? -42.570 -13.801 65.778 1.00 82.46 ? 399 LEU A CD1 1 ATOM 1632 C CD2 . LEU A 1 214 ? -43.368 -11.430 65.920 1.00 82.03 ? 399 LEU A CD2 1 ATOM 1633 N N . PRO A 1 215 ? -40.114 -9.404 68.869 1.00 79.48 ? 400 PRO A N 1 ATOM 1634 C CA . PRO A 1 215 ? -39.448 -9.138 70.141 1.00 80.11 ? 400 PRO A CA 1 ATOM 1635 C C . PRO A 1 215 ? -39.824 -10.138 71.232 1.00 80.64 ? 400 PRO A C 1 ATOM 1636 O O . PRO A 1 215 ? -40.913 -10.711 71.199 1.00 80.77 ? 400 PRO A O 1 ATOM 1637 C CB . PRO A 1 215 ? -39.937 -7.729 70.522 1.00 79.93 ? 400 PRO A CB 1 ATOM 1638 C CG . PRO A 1 215 ? -40.724 -7.227 69.361 1.00 79.96 ? 400 PRO A CG 1 ATOM 1639 C CD . PRO A 1 215 ? -41.159 -8.409 68.579 1.00 79.80 ? 400 PRO A CD 1 ATOM 1640 N N . GLU A 1 216 ? -38.911 -10.343 72.179 1.00 81.43 ? 401 GLU A N 1 ATOM 1641 C CA . GLU A 1 216 ? -39.182 -11.151 73.366 1.00 80.90 ? 401 GLU A CA 1 ATOM 1642 C C . GLU A 1 216 ? -39.687 -10.230 74.479 1.00 80.07 ? 401 GLU A C 1 ATOM 1643 O O . GLU A 1 216 ? -39.178 -9.122 74.651 1.00 79.90 ? 401 GLU A O 1 ATOM 1644 C CB . GLU A 1 216 ? -37.915 -11.892 73.808 1.00 82.01 ? 401 GLU A CB 1 ATOM 1645 C CG . GLU A 1 216 ? -38.171 -13.070 74.741 1.00 82.97 ? 401 GLU A CG 1 ATOM 1646 C CD . GLU A 1 216 ? -38.920 -14.210 74.064 1.00 84.22 ? 401 GLU A CD 1 ATOM 1647 O OE1 . GLU A 1 216 ? -38.414 -14.736 73.048 1.00 84.52 ? 401 GLU A OE1 1 ATOM 1648 O OE2 . GLU A 1 216 ? -40.010 -14.582 74.556 1.00 84.35 ? 401 GLU A OE2 1 ATOM 1649 N N . LEU A 1 217 ? -40.678 -10.700 75.232 1.00 79.87 ? 402 LEU A N 1 ATOM 1650 C CA . LEU A 1 217 ? -41.421 -9.846 76.163 1.00 80.20 ? 402 LEU A CA 1 ATOM 1651 C C . LEU A 1 217 ? -41.318 -10.349 77.598 1.00 80.71 ? 402 LEU A C 1 ATOM 1652 O O . LEU A 1 217 ? -41.269 -11.555 77.840 1.00 81.20 ? 402 LEU A O 1 ATOM 1653 C CB . LEU A 1 217 ? -42.891 -9.788 75.741 1.00 80.04 ? 402 LEU A CB 1 ATOM 1654 C CG . LEU A 1 217 ? -43.790 -8.746 76.408 1.00 79.89 ? 402 LEU A CG 1 ATOM 1655 C CD1 . LEU A 1 217 ? -43.256 -7.337 76.208 1.00 79.97 ? 402 LEU A CD1 1 ATOM 1656 C CD2 . LEU A 1 217 ? -45.193 -8.862 75.854 1.00 79.69 ? 402 LEU A CD2 1 ATOM 1657 N N . LYS A 1 218 ? -41.293 -9.411 78.545 1.00 81.01 ? 403 LYS A N 1 ATOM 1658 C CA . LYS A 1 218 ? -41.192 -9.734 79.971 1.00 80.37 ? 403 LYS A CA 1 ATOM 1659 C C . LYS A 1 218 ? -41.645 -8.544 80.821 1.00 79.71 ? 403 LYS A C 1 ATOM 1660 O O . LYS A 1 218 ? -41.133 -7.436 80.664 1.00 79.14 ? 403 LYS A O 1 ATOM 1661 C CB . LYS A 1 218 ? -39.754 -10.108 80.324 1.00 80.61 ? 403 LYS A CB 1 ATOM 1662 C CG . LYS A 1 218 ? -39.581 -10.714 81.711 1.00 80.94 ? 403 LYS A CG 1 ATOM 1663 C CD . LYS A 1 218 ? -38.151 -11.196 81.927 1.00 80.71 ? 403 LYS A CD 1 ATOM 1664 C CE . LYS A 1 218 ? -37.899 -12.544 81.260 1.00 80.82 ? 403 LYS A CE 1 ATOM 1665 N NZ . LYS A 1 218 ? -36.478 -12.700 80.839 1.00 81.01 ? 403 LYS A NZ 1 ATOM 1666 N N . CYS A 1 219 ? -42.605 -8.786 81.714 1.00 80.10 ? 404 CYS A N 1 ATOM 1667 C CA . CYS A 1 219 ? -43.180 -7.740 82.563 1.00 80.34 ? 404 CYS A CA 1 ATOM 1668 C C . CYS A 1 219 ? -42.975 -8.079 84.032 1.00 80.39 ? 404 CYS A C 1 ATOM 1669 O O . CYS A 1 219 ? -43.506 -9.077 84.518 1.00 80.81 ? 404 CYS A O 1 ATOM 1670 C CB . CYS A 1 219 ? -44.674 -7.593 82.280 1.00 81.24 ? 404 CYS A CB 1 ATOM 1671 S SG . CYS A 1 219 ? -45.066 -7.114 80.588 1.00 82.46 ? 404 CYS A SG 1 ATOM 1672 N N . LEU A 1 220 ? -42.219 -7.237 84.735 1.00 80.03 ? 405 LEU A N 1 ATOM 1673 C CA . LEU A 1 220 ? -41.839 -7.498 86.124 1.00 79.90 ? 405 LEU A CA 1 ATOM 1674 C C . LEU A 1 220 ? -42.065 -6.275 87.014 1.00 79.44 ? 405 LEU A C 1 ATOM 1675 O O . LEU A 1 220 ? -41.850 -5.141 86.583 1.00 79.00 ? 405 LEU A O 1 ATOM 1676 C CB . LEU A 1 220 ? -40.367 -7.901 86.188 1.00 80.04 ? 405 LEU A CB 1 ATOM 1677 C CG . LEU A 1 220 ? -39.989 -9.180 85.437 1.00 80.31 ? 405 LEU A CG 1 ATOM 1678 C CD1 . LEU A 1 220 ? -38.488 -9.253 85.223 1.00 80.14 ? 405 LEU A CD1 1 ATOM 1679 C CD2 . LEU A 1 220 ? -40.490 -10.407 86.185 1.00 80.61 ? 405 LEU A CD2 1 ATOM 1680 N N . LYS A 1 221 ? -42.506 -6.518 88.250 1.00 79.68 ? 406 LYS A N 1 ATOM 1681 C CA . LYS A 1 221 ? -42.569 -5.477 89.282 1.00 80.22 ? 406 LYS A CA 1 ATOM 1682 C C . LYS A 1 221 ? -41.782 -5.913 90.512 1.00 80.07 ? 406 LYS A C 1 ATOM 1683 O O . LYS A 1 221 ? -41.435 -7.088 90.648 1.00 79.89 ? 406 LYS A O 1 ATOM 1684 C CB . LYS A 1 221 ? -44.019 -5.165 89.671 1.00 80.50 ? 406 LYS A CB 1 ATOM 1685 C CG . LYS A 1 221 ? -44.666 -6.169 90.632 1.00 80.56 ? 406 LYS A CG 1 ATOM 1686 C CD . LYS A 1 221 ? -45.768 -5.517 91.460 1.00 80.60 ? 406 LYS A CD 1 ATOM 1687 C CE . LYS A 1 221 ? -46.158 -6.382 92.650 1.00 80.89 ? 406 LYS A CE 1 ATOM 1688 N NZ . LYS A 1 221 ? -46.936 -7.579 92.242 1.00 81.28 ? 406 LYS A NZ 1 ATOM 1689 N N . ASP A 1 222 ? -41.519 -4.964 91.410 1.00 80.38 ? 407 ASP A N 1 ATOM 1690 C CA . ASP A 1 222 ? -40.757 -5.229 92.635 1.00 80.74 ? 407 ASP A CA 1 ATOM 1691 C C . ASP A 1 222 ? -39.584 -6.171 92.362 1.00 81.31 ? 407 ASP A C 1 ATOM 1692 O O . ASP A 1 222 ? -39.399 -7.171 93.057 1.00 81.56 ? 407 ASP A O 1 ATOM 1693 C CB . ASP A 1 222 ? -41.670 -5.815 93.722 1.00 80.69 ? 407 ASP A CB 1 ATOM 1694 C CG . ASP A 1 222 ? -42.634 -4.791 94.297 1.00 80.92 ? 407 ASP A CG 1 ATOM 1695 O OD1 . ASP A 1 222 ? -42.230 -3.624 94.489 1.00 81.00 ? 407 ASP A OD1 1 ATOM 1696 O OD2 . ASP A 1 222 ? -43.796 -5.159 94.573 1.00 80.99 ? 407 ASP A OD2 1 ATOM 1697 N N . GLY A 1 223 ? -38.808 -5.850 91.330 1.00 81.64 ? 408 GLY A N 1 ATOM 1698 C CA . GLY A 1 223 ? -37.674 -6.673 90.931 1.00 81.40 ? 408 GLY A CA 1 ATOM 1699 C C . GLY A 1 223 ? -38.045 -7.745 89.928 1.00 81.25 ? 408 GLY A C 1 ATOM 1700 O O . GLY A 1 223 ? -37.943 -7.533 88.721 1.00 81.18 ? 408 GLY A O 1 ATOM 1701 N N . THR A 1 224 ? -38.480 -8.898 90.434 1.00 81.40 ? 409 THR A N 1 ATOM 1702 C CA . THR A 1 224 ? -38.694 -10.086 89.605 1.00 81.60 ? 409 THR A CA 1 ATOM 1703 C C . THR A 1 224 ? -40.037 -10.760 89.895 1.00 81.42 ? 409 THR A C 1 ATOM 1704 O O . THR A 1 224 ? -40.094 -11.966 90.144 1.00 81.34 ? 409 THR A O 1 ATOM 1705 C CB . THR A 1 224 ? -37.564 -11.118 89.825 1.00 82.09 ? 409 THR A CB 1 ATOM 1706 O OG1 . THR A 1 224 ? -37.564 -11.544 91.194 1.00 82.80 ? 409 THR A OG1 1 ATOM 1707 C CG2 . THR A 1 224 ? -36.207 -10.518 89.485 1.00 81.67 ? 409 THR A CG2 1 ATOM 1708 N N . PHE A 1 225 ? -41.112 -9.976 89.864 1.00 81.44 ? 410 PHE A N 1 ATOM 1709 C CA . PHE A 1 225 ? -42.464 -10.506 90.034 1.00 81.53 ? 410 PHE A CA 1 ATOM 1710 C C . PHE A 1 225 ? -43.174 -10.515 88.675 1.00 81.45 ? 410 PHE A C 1 ATOM 1711 O O . PHE A 1 225 ? -43.692 -9.487 88.237 1.00 80.96 ? 410 PHE A O 1 ATOM 1712 C CB . PHE A 1 225 ? -43.244 -9.667 91.049 1.00 81.77 ? 410 PHE A CB 1 ATOM 1713 C CG . PHE A 1 225 ? -44.507 -10.322 91.535 1.00 81.69 ? 410 PHE A CG 1 ATOM 1714 C CD1 . PHE A 1 225 ? -44.503 -11.097 92.689 1.00 81.92 ? 410 PHE A CD1 1 ATOM 1715 C CD2 . PHE A 1 225 ? -45.701 -10.163 90.841 1.00 81.82 ? 410 PHE A CD2 1 ATOM 1716 C CE1 . PHE A 1 225 ? -45.669 -11.703 93.144 1.00 81.90 ? 410 PHE A CE1 1 ATOM 1717 C CE2 . PHE A 1 225 ? -46.872 -10.766 91.288 1.00 81.82 ? 410 PHE A CE2 1 ATOM 1718 C CZ . PHE A 1 225 ? -46.856 -11.537 92.442 1.00 81.91 ? 410 PHE A CZ 1 ATOM 1719 N N . PRO A 1 226 ? -43.196 -11.681 88.001 1.00 81.72 ? 411 PRO A N 1 ATOM 1720 C CA . PRO A 1 226 ? -43.680 -11.735 86.624 1.00 81.66 ? 411 PRO A CA 1 ATOM 1721 C C . PRO A 1 226 ? -45.191 -11.555 86.490 1.00 81.61 ? 411 PRO A C 1 ATOM 1722 O O . PRO A 1 226 ? -45.954 -12.100 87.288 1.00 81.69 ? 411 PRO A O 1 ATOM 1723 C CB . PRO A 1 226 ? -43.269 -13.139 86.169 1.00 81.91 ? 411 PRO A CB 1 ATOM 1724 C CG . PRO A 1 226 ? -43.247 -13.940 87.410 1.00 81.93 ? 411 PRO A CG 1 ATOM 1725 C CD . PRO A 1 226 ? -42.776 -13.009 88.485 1.00 81.95 ? 411 PRO A CD 1 ATOM 1726 N N . LEU A 1 227 ? -45.605 -10.787 85.484 1.00 81.68 ? 412 LEU A N 1 ATOM 1727 C CA . LEU A 1 227 ? -47.010 -10.701 85.096 1.00 81.70 ? 412 LEU A CA 1 ATOM 1728 C C . LEU A 1 227 ? -47.269 -11.769 84.038 1.00 81.78 ? 412 LEU A C 1 ATOM 1729 O O . LEU A 1 227 ? -46.662 -11.733 82.968 1.00 81.57 ? 412 LEU A O 1 ATOM 1730 C CB . LEU A 1 227 ? -47.327 -9.313 84.536 1.00 81.34 ? 412 LEU A CB 1 ATOM 1731 C CG . LEU A 1 227 ? -48.786 -9.018 84.185 1.00 81.58 ? 412 LEU A CG 1 ATOM 1732 C CD1 . LEU A 1 227 ? -49.704 -9.250 85.381 1.00 81.65 ? 412 LEU A CD1 1 ATOM 1733 C CD2 . LEU A 1 227 ? -48.920 -7.590 83.677 1.00 81.64 ? 412 LEU A CD2 1 ATOM 1734 N N . PRO A 1 228 ? -48.159 -12.736 84.336 1.00 82.15 ? 413 PRO A N 1 ATOM 1735 C CA . PRO A 1 228 ? -48.354 -13.871 83.435 1.00 81.91 ? 413 PRO A CA 1 ATOM 1736 C C . PRO A 1 228 ? -49.203 -13.518 82.207 1.00 81.65 ? 413 PRO A C 1 ATOM 1737 O O . PRO A 1 228 ? -50.414 -13.753 82.190 1.00 81.04 ? 413 PRO A O 1 ATOM 1738 C CB . PRO A 1 228 ? -49.051 -14.899 84.328 1.00 82.03 ? 413 PRO A CB 1 ATOM 1739 C CG . PRO A 1 228 ? -49.832 -14.079 85.285 1.00 82.23 ? 413 PRO A CG 1 ATOM 1740 C CD . PRO A 1 228 ? -49.030 -12.826 85.524 1.00 82.20 ? 413 PRO A CD 1 ATOM 1741 N N . ILE A 1 229 ? -48.549 -12.965 81.188 1.00 81.68 ? 414 ILE A N 1 ATOM 1742 C CA . ILE A 1 229 ? -49.214 -12.565 79.950 1.00 81.53 ? 414 ILE A CA 1 ATOM 1743 C C . ILE A 1 229 ? -49.747 -13.790 79.214 1.00 81.29 ? 414 ILE A C 1 ATOM 1744 O O . ILE A 1 229 ? -49.020 -14.768 79.026 1.00 81.34 ? 414 ILE A O 1 ATOM 1745 C CB . ILE A 1 229 ? -48.251 -11.813 79.009 1.00 81.78 ? 414 ILE A CB 1 ATOM 1746 C CG1 . ILE A 1 229 ? -47.816 -10.484 79.632 1.00 81.88 ? 414 ILE A CG1 1 ATOM 1747 C CG2 . ILE A 1 229 ? -48.911 -11.562 77.660 1.00 81.77 ? 414 ILE A CG2 1 ATOM 1748 C CD1 . ILE A 1 229 ? -46.682 -9.813 78.889 1.00 81.75 ? 414 ILE A CD1 1 ATOM 1749 N N . GLY A 1 230 ? -51.017 -13.735 78.813 1.00 80.82 ? 415 GLY A N 1 ATOM 1750 C CA . GLY A 1 230 ? -51.654 -14.835 78.089 1.00 80.72 ? 415 GLY A CA 1 ATOM 1751 C C . GLY A 1 230 ? -52.310 -15.879 78.980 1.00 80.57 ? 415 GLY A C 1 ATOM 1752 O O . GLY A 1 230 ? -53.247 -16.554 78.560 1.00 80.44 ? 415 GLY A O 1 ATOM 1753 N N . GLU A 1 231 ? -51.820 -16.022 80.209 1.00 80.76 ? 416 GLU A N 1 ATOM 1754 C CA . GLU A 1 231 ? -52.372 -17.000 81.144 1.00 80.93 ? 416 GLU A CA 1 ATOM 1755 C C . GLU A 1 231 ? -53.595 -16.425 81.846 1.00 80.16 ? 416 GLU A C 1 ATOM 1756 O O . GLU A 1 231 ? -53.681 -15.217 82.070 1.00 79.76 ? 416 GLU A O 1 ATOM 1757 C CB . GLU A 1 231 ? -51.326 -17.403 82.186 1.00 81.80 ? 416 GLU A CB 1 ATOM 1758 C CG . GLU A 1 231 ? -50.025 -17.951 81.603 1.00 82.19 ? 416 GLU A CG 1 ATOM 1759 C CD . GLU A 1 231 ? -48.974 -18.235 82.667 1.00 82.54 ? 416 GLU A CD 1 ATOM 1760 O OE1 . GLU A 1 231 ? -49.340 -18.379 83.855 1.00 82.95 ? 416 GLU A OE1 1 ATOM 1761 O OE2 . GLU A 1 231 ? -47.778 -18.319 82.312 1.00 83.34 ? 416 GLU A OE2 1 ATOM 1762 N N . SER A 1 232 ? -54.541 -17.298 82.185 1.00 79.72 ? 417 SER A N 1 ATOM 1763 C CA . SER A 1 232 ? -55.714 -16.908 82.958 1.00 79.40 ? 417 SER A CA 1 ATOM 1764 C C . SER A 1 232 ? -55.452 -17.202 84.429 1.00 78.91 ? 417 SER A C 1 ATOM 1765 O O . SER A 1 232 ? -55.326 -18.362 84.820 1.00 79.04 ? 417 SER A O 1 ATOM 1766 C CB . SER A 1 232 ? -56.951 -17.669 82.480 1.00 79.44 ? 417 SER A CB 1 ATOM 1767 O OG . SER A 1 232 ? -58.110 -17.241 83.174 1.00 79.58 ? 417 SER A OG 1 ATOM 1768 N N . VAL A 1 233 ? -55.368 -16.148 85.238 1.00 78.59 ? 418 VAL A N 1 ATOM 1769 C CA . VAL A 1 233 ? -54.997 -16.281 86.647 1.00 78.45 ? 418 VAL A CA 1 ATOM 1770 C C . VAL A 1 233 ? -56.081 -15.749 87.579 1.00 78.59 ? 418 VAL A C 1 ATOM 1771 O O . VAL A 1 233 ? -56.881 -14.894 87.197 1.00 79.19 ? 418 VAL A O 1 ATOM 1772 C CB . VAL A 1 233 ? -53.683 -15.532 86.948 1.00 77.87 ? 418 VAL A CB 1 ATOM 1773 C CG1 . VAL A 1 233 ? -52.581 -15.994 86.000 1.00 78.06 ? 418 VAL A CG1 1 ATOM 1774 C CG2 . VAL A 1 233 ? -53.888 -14.022 86.849 1.00 76.97 ? 418 VAL A CG2 1 ATOM 1775 N N . THR A 1 234 ? -56.100 -16.266 88.805 1.00 78.14 ? 419 THR A N 1 ATOM 1776 C CA . THR A 1 234 ? -56.944 -15.718 89.857 1.00 77.79 ? 419 THR A CA 1 ATOM 1777 C C . THR A 1 234 ? -56.306 -14.427 90.365 1.00 77.28 ? 419 THR A C 1 ATOM 1778 O O . THR A 1 234 ? -55.157 -14.431 90.810 1.00 77.09 ? 419 THR A O 1 ATOM 1779 C CB . THR A 1 234 ? -57.097 -16.704 91.036 1.00 78.21 ? 419 THR A CB 1 ATOM 1780 O OG1 . THR A 1 234 ? -57.528 -17.980 90.548 1.00 78.38 ? 419 THR A OG1 1 ATOM 1781 C CG2 . THR A 1 234 ? -58.108 -16.182 92.048 1.00 78.25 ? 419 THR A CG2 1 ATOM 1782 N N . VAL A 1 235 ? -57.047 -13.325 90.285 1.00 77.13 ? 420 VAL A N 1 ATOM 1783 C CA . VAL A 1 235 ? -56.543 -12.027 90.724 1.00 77.02 ? 420 VAL A CA 1 ATOM 1784 C C . VAL A 1 235 ? -56.493 -11.952 92.249 1.00 76.97 ? 420 VAL A C 1 ATOM 1785 O O . VAL A 1 235 ? -57.487 -12.213 92.927 1.00 76.74 ? 420 VAL A O 1 ATOM 1786 C CB . VAL A 1 235 ? -57.407 -10.872 90.184 1.00 76.63 ? 420 VAL A CB 1 ATOM 1787 C CG1 . VAL A 1 235 ? -56.972 -9.545 90.791 1.00 76.54 ? 420 VAL A CG1 1 ATOM 1788 C CG2 . VAL A 1 235 ? -57.322 -10.819 88.670 1.00 76.61 ? 420 VAL A CG2 1 ATOM 1789 N N . THR A 1 236 ? -55.322 -11.601 92.775 1.00 77.33 ? 421 THR A N 1 ATOM 1790 C CA . THR A 1 236 ? -55.117 -11.434 94.210 1.00 77.22 ? 421 THR A CA 1 ATOM 1791 C C . THR A 1 236 ? -54.434 -10.091 94.475 1.00 77.93 ? 421 THR A C 1 ATOM 1792 O O . THR A 1 236 ? -54.033 -9.395 93.539 1.00 78.60 ? 421 THR A O 1 ATOM 1793 C CB . THR A 1 236 ? -54.245 -12.567 94.780 1.00 76.59 ? 421 THR A CB 1 ATOM 1794 O OG1 . THR A 1 236 ? -52.964 -12.559 94.139 1.00 76.38 ? 421 THR A OG1 1 ATOM 1795 C CG2 . THR A 1 236 ? -54.910 -13.918 94.559 1.00 76.29 ? 421 THR A CG2 1 ATOM 1796 N N . ARG A 1 237 ? -54.297 -9.737 95.750 1.00 77.96 ? 422 ARG A N 1 ATOM 1797 C CA . ARG A 1 237 ? -53.627 -8.492 96.139 1.00 77.72 ? 422 ARG A CA 1 ATOM 1798 C C . ARG A 1 237 ? -52.134 -8.504 95.800 1.00 77.33 ? 422 ARG A C 1 ATOM 1799 O O . ARG A 1 237 ? -51.515 -7.446 95.687 1.00 76.97 ? 422 ARG A O 1 ATOM 1800 C CB . ARG A 1 237 ? -53.816 -8.222 97.636 1.00 77.60 ? 422 ARG A CB 1 ATOM 1801 C CG . ARG A 1 237 ? -55.230 -7.818 98.020 1.00 77.43 ? 422 ARG A CG 1 ATOM 1802 C CD . ARG A 1 237 ? -55.329 -7.495 99.503 0.50 77.56 ? 422 ARG A CD 1 ATOM 1803 N NE . ARG A 1 237 ? -56.616 -6.894 99.852 0.50 77.59 ? 422 ARG A NE 1 ATOM 1804 C CZ . ARG A 1 237 ? -56.971 -6.521 101.081 0.50 77.53 ? 422 ARG A CZ 1 ATOM 1805 N NH1 . ARG A 1 237 ? -56.139 -6.683 102.106 0.50 77.50 ? 422 ARG A NH1 1 ATOM 1806 N NH2 . ARG A 1 237 ? -58.168 -5.983 101.288 0.50 77.50 ? 422 ARG A NH2 1 ATOM 1807 N N . ASP A 1 238 ? -51.566 -9.700 95.640 1.00 77.74 ? 423 ASP A N 1 ATOM 1808 C CA . ASP A 1 238 ? -50.148 -9.852 95.293 1.00 78.58 ? 423 ASP A CA 1 ATOM 1809 C C . ASP A 1 238 ? -49.836 -9.343 93.882 1.00 78.56 ? 423 ASP A C 1 ATOM 1810 O O . ASP A 1 238 ? -48.717 -8.907 93.612 1.00 78.76 ? 423 ASP A O 1 ATOM 1811 C CB . ASP A 1 238 ? -49.717 -11.320 95.412 1.00 80.23 ? 423 ASP A CB 1 ATOM 1812 C CG . ASP A 1 238 ? -49.863 -11.866 96.828 1.00 81.92 ? 423 ASP A CG 1 ATOM 1813 O OD1 . ASP A 1 238 ? -50.821 -11.475 97.531 1.00 82.55 ? 423 ASP A OD1 1 ATOM 1814 O OD2 . ASP A 1 238 ? -49.021 -12.697 97.232 1.00 82.54 ? 423 ASP A OD2 1 ATOM 1815 N N . LEU A 1 239 ? -50.824 -9.402 92.992 1.00 78.42 ? 424 LEU A N 1 ATOM 1816 C CA . LEU A 1 239 ? -50.662 -8.933 91.611 1.00 78.38 ? 424 LEU A CA 1 ATOM 1817 C C . LEU A 1 239 ? -50.764 -7.410 91.477 1.00 78.09 ? 424 LEU A C 1 ATOM 1818 O O . LEU A 1 239 ? -50.403 -6.855 90.439 1.00 77.51 ? 424 LEU A O 1 ATOM 1819 C CB . LEU A 1 239 ? -51.698 -9.598 90.699 1.00 78.52 ? 424 LEU A CB 1 ATOM 1820 C CG . LEU A 1 239 ? -51.485 -11.093 90.452 1.00 78.76 ? 424 LEU A CG 1 ATOM 1821 C CD1 . LEU A 1 239 ? -52.780 -11.759 90.019 1.00 79.23 ? 424 LEU A CD1 1 ATOM 1822 C CD2 . LEU A 1 239 ? -50.388 -11.316 89.418 1.00 78.48 ? 424 LEU A CD2 1 ATOM 1823 N N . GLU A 1 240 ? -51.260 -6.740 92.516 1.00 78.10 ? 425 GLU A N 1 ATOM 1824 C CA . GLU A 1 240 ? -51.420 -5.285 92.487 1.00 77.93 ? 425 GLU A CA 1 ATOM 1825 C C . GLU A 1 240 ? -50.064 -4.583 92.439 1.00 77.31 ? 425 GLU A C 1 ATOM 1826 O O . GLU A 1 240 ? -49.125 -4.995 93.118 1.00 77.40 ? 425 GLU A O 1 ATOM 1827 C CB . GLU A 1 240 ? -52.205 -4.808 93.712 1.00 78.04 ? 425 GLU A CB 1 ATOM 1828 C CG . GLU A 1 240 ? -52.638 -3.350 93.643 1.00 78.29 ? 425 GLU A CG 1 ATOM 1829 C CD . GLU A 1 240 ? -53.565 -2.962 94.781 1.00 78.71 ? 425 GLU A CD 1 ATOM 1830 O OE1 . GLU A 1 240 ? -54.657 -2.422 94.501 1.00 79.03 ? 425 GLU A OE1 1 ATOM 1831 O OE2 . GLU A 1 240 ? -53.205 -3.203 95.955 1.00 78.99 ? 425 GLU A OE2 1 ATOM 1832 N N . GLY A 1 241 ? -49.973 -3.526 91.633 1.00 76.79 ? 426 GLY A N 1 ATOM 1833 C CA . GLY A 1 241 ? -48.749 -2.728 91.529 1.00 76.76 ? 426 GLY A CA 1 ATOM 1834 C C . GLY A 1 241 ? -48.438 -2.298 90.109 1.00 76.10 ? 426 GLY A C 1 ATOM 1835 O O . GLY A 1 241 ? -49.175 -2.618 89.178 1.00 75.78 ? 426 GLY A O 1 ATOM 1836 N N . THR A 1 242 ? -47.338 -1.565 89.949 1.00 76.01 ? 427 THR A N 1 ATOM 1837 C CA . THR A 1 242 ? -46.885 -1.110 88.636 1.00 76.15 ? 427 THR A CA 1 ATOM 1838 C C . THR A 1 242 ? -45.795 -2.032 88.104 1.00 75.91 ? 427 THR A C 1 ATOM 1839 O O . THR A 1 242 ? -44.747 -2.189 88.731 1.00 75.95 ? 427 THR A O 1 ATOM 1840 C CB . THR A 1 242 ? -46.332 0.330 88.694 1.00 75.94 ? 427 THR A CB 1 ATOM 1841 O OG1 . THR A 1 242 ? -47.377 1.234 89.073 1.00 76.08 ? 427 THR A OG1 1 ATOM 1842 C CG2 . THR A 1 242 ? -45.774 0.750 87.338 1.00 75.75 ? 427 THR A CG2 1 ATOM 1843 N N . TYR A 1 243 ? -46.050 -2.636 86.945 1.00 75.69 ? 428 TYR A N 1 ATOM 1844 C CA . TYR A 1 243 ? -45.075 -3.500 86.286 1.00 76.18 ? 428 TYR A CA 1 ATOM 1845 C C . TYR A 1 243 ? -44.298 -2.721 85.231 1.00 76.42 ? 428 TYR A C 1 ATOM 1846 O O . TYR A 1 243 ? -44.809 -1.758 84.656 1.00 75.96 ? 428 TYR A O 1 ATOM 1847 C CB . TYR A 1 243 ? -45.770 -4.686 85.620 1.00 75.61 ? 428 TYR A CB 1 ATOM 1848 C CG . TYR A 1 243 ? -46.480 -5.610 86.577 1.00 75.53 ? 428 TYR A CG 1 ATOM 1849 C CD1 . TYR A 1 243 ? -47.737 -5.290 87.078 1.00 75.60 ? 428 TYR A CD1 1 ATOM 1850 C CD2 . TYR A 1 243 ? -45.905 -6.814 86.969 1.00 75.61 ? 428 TYR A CD2 1 ATOM 1851 C CE1 . TYR A 1 243 ? -48.398 -6.137 87.951 1.00 75.48 ? 428 TYR A CE1 1 ATOM 1852 C CE2 . TYR A 1 243 ? -46.559 -7.670 87.842 1.00 75.63 ? 428 TYR A CE2 1 ATOM 1853 C CZ . TYR A 1 243 ? -47.805 -7.325 88.328 1.00 75.55 ? 428 TYR A CZ 1 ATOM 1854 O OH . TYR A 1 243 ? -48.460 -8.167 89.191 1.00 75.71 ? 428 TYR A OH 1 ATOM 1855 N N . LEU A 1 244 ? -43.062 -3.146 84.986 1.00 76.99 ? 429 LEU A N 1 ATOM 1856 C CA . LEU A 1 244 ? -42.246 -2.587 83.920 1.00 77.29 ? 429 LEU A CA 1 ATOM 1857 C C . LEU A 1 244 ? -42.098 -3.629 82.815 1.00 78.18 ? 429 LEU A C 1 ATOM 1858 O O . LEU A 1 244 ? -41.316 -4.570 82.943 1.00 79.08 ? 429 LEU A O 1 ATOM 1859 C CB . LEU A 1 244 ? -40.875 -2.173 84.459 1.00 77.30 ? 429 LEU A CB 1 ATOM 1860 C CG . LEU A 1 244 ? -39.891 -1.554 83.458 1.00 77.70 ? 429 LEU A CG 1 ATOM 1861 C CD1 . LEU A 1 244 ? -40.480 -0.307 82.810 1.00 78.08 ? 429 LEU A CD1 1 ATOM 1862 C CD2 . LEU A 1 244 ? -38.568 -1.230 84.141 1.00 77.60 ? 429 LEU A CD2 1 ATOM 1863 N N . CYS A 1 245 ? -42.869 -3.462 81.741 1.00 77.97 ? 430 CYS A N 1 ATOM 1864 C CA . CYS A 1 245 ? -42.809 -4.365 80.592 1.00 78.04 ? 430 CYS A CA 1 ATOM 1865 C C . CYS A 1 245 ? -41.677 -3.959 79.664 1.00 77.87 ? 430 CYS A C 1 ATOM 1866 O O . CYS A 1 245 ? -41.584 -2.799 79.276 1.00 78.10 ? 430 CYS A O 1 ATOM 1867 C CB . CYS A 1 245 ? -44.134 -4.353 79.827 1.00 79.69 ? 430 CYS A CB 1 ATOM 1868 S SG . CYS A 1 245 ? -45.485 -5.129 80.728 1.00 81.80 ? 430 CYS A SG 1 ATOM 1869 N N . ARG A 1 246 ? -40.828 -4.922 79.309 1.00 77.36 ? 431 ARG A N 1 ATOM 1870 C CA . ARG A 1 246 ? -39.661 -4.659 78.472 1.00 76.99 ? 431 ARG A CA 1 ATOM 1871 C C . ARG A 1 246 ? -39.666 -5.559 77.238 1.00 76.24 ? 431 ARG A C 1 ATOM 1872 O O . ARG A 1 246 ? -39.666 -6.784 77.360 1.00 75.88 ? 431 ARG A O 1 ATOM 1873 C CB . ARG A 1 246 ? -38.381 -4.883 79.278 1.00 77.37 ? 431 ARG A CB 1 ATOM 1874 C CG . ARG A 1 246 ? -37.131 -4.274 78.655 1.00 77.59 ? 431 ARG A CG 1 ATOM 1875 C CD . ARG A 1 246 ? -35.893 -4.564 79.491 1.00 77.81 ? 431 ARG A CD 1 ATOM 1876 N NE . ARG A 1 246 ? -36.008 -4.050 80.859 1.00 78.23 ? 431 ARG A NE 1 ATOM 1877 C CZ . ARG A 1 246 ? -35.778 -2.787 81.227 1.00 78.51 ? 431 ARG A CZ 1 ATOM 1878 N NH1 . ARG A 1 246 ? -35.417 -1.866 80.336 1.00 78.91 ? 431 ARG A NH1 1 ATOM 1879 N NH2 . ARG A 1 246 ? -35.915 -2.439 82.502 1.00 78.30 ? 431 ARG A NH2 1 ATOM 1880 N N . ALA A 1 247 ? -39.684 -4.941 76.057 1.00 76.30 ? 432 ALA A N 1 ATOM 1881 C CA . ALA A 1 247 ? -39.605 -5.666 74.783 1.00 75.70 ? 432 ALA A CA 1 ATOM 1882 C C . ALA A 1 247 ? -38.170 -5.637 74.275 1.00 75.09 ? 432 ALA A C 1 ATOM 1883 O O . ALA A 1 247 ? -37.507 -4.603 74.347 1.00 74.54 ? 432 ALA A O 1 ATOM 1884 C CB . ALA A 1 247 ? -40.535 -5.043 73.761 1.00 74.87 ? 432 ALA A CB 1 ATOM 1885 N N . ARG A 1 248 ? -37.704 -6.770 73.751 1.00 75.37 ? 433 ARG A N 1 ATOM 1886 C CA . ARG A 1 248 ? -36.293 -6.946 73.401 1.00 75.40 ? 433 ARG A CA 1 ATOM 1887 C C . ARG A 1 248 ? -36.120 -7.642 72.054 1.00 75.37 ? 433 ARG A C 1 ATOM 1888 O O . ARG A 1 248 ? -36.767 -8.651 71.784 1.00 75.95 ? 433 ARG A O 1 ATOM 1889 C CB . ARG A 1 248 ? -35.604 -7.769 74.489 1.00 75.72 ? 433 ARG A CB 1 ATOM 1890 C CG . ARG A 1 248 ? -34.090 -7.864 74.359 1.00 75.81 ? 433 ARG A CG 1 ATOM 1891 C CD . ARG A 1 248 ? -33.505 -8.722 75.467 1.00 75.82 ? 433 ARG A CD 1 ATOM 1892 N NE . ARG A 1 248 ? -33.796 -8.171 76.788 1.00 75.93 ? 433 ARG A NE 1 ATOM 1893 C CZ . ARG A 1 248 ? -33.107 -7.195 77.376 1.00 76.29 ? 433 ARG A CZ 1 ATOM 1894 N NH1 . ARG A 1 248 ? -32.059 -6.640 76.773 1.00 76.93 ? 433 ARG A NH1 1 ATOM 1895 N NH2 . ARG A 1 248 ? -33.467 -6.769 78.580 1.00 76.13 ? 433 ARG A NH2 1 ATOM 1896 N N . SER A 1 249 ? -35.241 -7.096 71.217 1.00 75.03 ? 434 SER A N 1 ATOM 1897 C CA . SER A 1 249 ? -34.864 -7.724 69.947 1.00 74.88 ? 434 SER A CA 1 ATOM 1898 C C . SER A 1 249 ? -33.551 -7.129 69.450 1.00 75.23 ? 434 SER A C 1 ATOM 1899 O O . SER A 1 249 ? -33.038 -6.175 70.037 1.00 75.43 ? 434 SER A O 1 ATOM 1900 C CB . SER A 1 249 ? -35.949 -7.515 68.891 1.00 74.71 ? 434 SER A CB 1 ATOM 1901 O OG . SER A 1 249 ? -35.866 -6.218 68.326 1.00 74.73 ? 434 SER A OG 1 ATOM 1902 N N . THR A 1 250 ? -33.030 -7.668 68.347 1.00 75.04 ? 435 THR A N 1 ATOM 1903 C CA . THR A 1 250 ? -31.741 -7.218 67.808 1.00 74.75 ? 435 THR A CA 1 ATOM 1904 C C . THR A 1 250 ? -31.766 -5.772 67.300 1.00 74.39 ? 435 THR A C 1 ATOM 1905 O O . THR A 1 250 ? -30.714 -5.192 67.033 1.00 74.45 ? 435 THR A O 1 ATOM 1906 C CB . THR A 1 250 ? -31.241 -8.129 66.664 1.00 73.98 ? 435 THR A CB 1 ATOM 1907 O OG1 . THR A 1 250 ? -32.223 -8.182 65.624 1.00 74.25 ? 435 THR A OG1 1 ATOM 1908 C CG2 . THR A 1 250 ? -30.961 -9.534 67.174 1.00 73.48 ? 435 THR A CG2 1 ATOM 1909 N N . GLN A 1 251 ? -32.959 -5.196 67.175 1.00 74.50 ? 436 GLN A N 1 ATOM 1910 C CA . GLN A 1 251 ? -33.111 -3.834 66.669 1.00 75.23 ? 436 GLN A CA 1 ATOM 1911 C C . GLN A 1 251 ? -33.231 -2.774 67.765 1.00 75.80 ? 436 GLN A C 1 ATOM 1912 O O . GLN A 1 251 ? -33.183 -1.579 67.471 1.00 76.55 ? 436 GLN A O 1 ATOM 1913 C CB . GLN A 1 251 ? -34.322 -3.761 65.737 1.00 75.00 ? 436 GLN A CB 1 ATOM 1914 C CG . GLN A 1 251 ? -34.150 -4.549 64.461 1.00 75.12 ? 436 GLN A CG 1 ATOM 1915 C CD . GLN A 1 251 ? -32.911 -4.141 63.700 1.00 75.35 ? 436 GLN A CD 1 ATOM 1916 O OE1 . GLN A 1 251 ? -32.736 -2.970 63.363 1.00 75.36 ? 436 GLN A OE1 1 ATOM 1917 N NE2 . GLN A 1 251 ? -32.034 -5.103 63.435 1.00 75.59 ? 436 GLN A NE2 1 ATOM 1918 N N . GLY A 1 252 ? -33.387 -3.197 69.017 1.00 75.61 ? 437 GLY A N 1 ATOM 1919 C CA . GLY A 1 252 ? -33.428 -2.250 70.130 1.00 75.58 ? 437 GLY A CA 1 ATOM 1920 C C . GLY A 1 252 ? -34.157 -2.758 71.356 1.00 75.32 ? 437 GLY A C 1 ATOM 1921 O O . GLY A 1 252 ? -34.278 -3.964 71.568 1.00 75.04 ? 437 GLY A O 1 ATOM 1922 N N . GLU A 1 253 ? -34.646 -1.818 72.161 1.00 75.69 ? 438 GLU A N 1 ATOM 1923 C CA . GLU A 1 253 ? -35.267 -2.129 73.445 1.00 75.94 ? 438 GLU A CA 1 ATOM 1924 C C . GLU A 1 253 ? -36.288 -1.049 73.811 1.00 75.75 ? 438 GLU A C 1 ATOM 1925 O O . GLU A 1 253 ? -36.017 0.141 73.659 1.00 75.84 ? 438 GLU A O 1 ATOM 1926 C CB . GLU A 1 253 ? -34.189 -2.216 74.527 1.00 75.91 ? 438 GLU A CB 1 ATOM 1927 C CG . GLU A 1 253 ? -34.596 -2.995 75.762 1.00 76.05 ? 438 GLU A CG 1 ATOM 1928 C CD . GLU A 1 253 ? -33.555 -2.921 76.866 0.50 76.16 ? 438 GLU A CD 1 ATOM 1929 O OE1 . GLU A 1 253 ? -33.197 -1.798 77.280 0.50 76.34 ? 438 GLU A OE1 1 ATOM 1930 O OE2 . GLU A 1 253 ? -33.101 -3.987 77.326 0.50 76.12 ? 438 GLU A OE2 1 ATOM 1931 N N . VAL A 1 254 ? -37.458 -1.471 74.287 1.00 75.96 ? 439 VAL A N 1 ATOM 1932 C CA . VAL A 1 254 ? -38.528 -0.544 74.671 1.00 76.87 ? 439 VAL A CA 1 ATOM 1933 C C . VAL A 1 254 ? -39.141 -0.948 76.010 1.00 76.90 ? 439 VAL A C 1 ATOM 1934 O O . VAL A 1 254 ? -39.102 -2.120 76.387 1.00 76.38 ? 439 VAL A O 1 ATOM 1935 C CB . VAL A 1 254 ? -39.639 -0.506 73.601 1.00 77.47 ? 439 VAL A CB 1 ATOM 1936 C CG1 . VAL A 1 254 ? -40.733 0.479 73.989 1.00 77.56 ? 439 VAL A CG1 1 ATOM 1937 C CG2 . VAL A 1 254 ? -39.057 -0.138 72.252 1.00 78.31 ? 439 VAL A CG2 1 ATOM 1938 N N . THR A 1 255 ? -39.696 0.029 76.726 1.00 77.47 ? 440 THR A N 1 ATOM 1939 C CA . THR A 1 255 ? -40.395 -0.227 77.985 1.00 78.06 ? 440 THR A CA 1 ATOM 1940 C C . THR A 1 255 ? -41.763 0.453 78.035 1.00 78.25 ? 440 THR A C 1 ATOM 1941 O O . THR A 1 255 ? -41.973 1.498 77.418 1.00 78.51 ? 440 THR A O 1 ATOM 1942 C CB . THR A 1 255 ? -39.573 0.251 79.198 1.00 78.93 ? 440 THR A CB 1 ATOM 1943 O OG1 . THR A 1 255 ? -39.341 1.663 79.103 1.00 79.56 ? 440 THR A OG1 1 ATOM 1944 C CG2 . THR A 1 255 ? -38.240 -0.478 79.266 1.00 79.26 ? 440 THR A CG2 1 ATOM 1945 N N . ARG A 1 256 ? -42.688 -0.157 78.770 1.00 78.36 ? 441 ARG A N 1 ATOM 1946 C CA . ARG A 1 256 ? -43.981 0.453 79.070 1.00 78.58 ? 441 ARG A CA 1 ATOM 1947 C C . ARG A 1 256 ? -44.411 0.074 80.482 1.00 78.89 ? 441 ARG A C 1 ATOM 1948 O O . ARG A 1 256 ? -44.279 -1.083 80.886 1.00 79.07 ? 441 ARG A O 1 ATOM 1949 C CB . ARG A 1 256 ? -45.042 0.002 78.066 1.00 78.46 ? 441 ARG A CB 1 ATOM 1950 C CG . ARG A 1 256 ? -46.486 0.273 78.510 1.00 78.77 ? 441 ARG A CG 1 ATOM 1951 C CD . ARG A 1 256 ? -47.478 0.035 77.385 1.00 79.29 ? 441 ARG A CD 1 ATOM 1952 N NE . ARG A 1 256 ? -47.424 1.093 76.375 1.00 79.86 ? 441 ARG A NE 1 ATOM 1953 C CZ . ARG A 1 256 ? -48.111 2.235 76.425 1.00 80.00 ? 441 ARG A CZ 1 ATOM 1954 N NH1 . ARG A 1 256 ? -48.925 2.507 77.446 1.00 79.91 ? 441 ARG A NH1 1 ATOM 1955 N NH2 . ARG A 1 256 ? -47.979 3.120 75.441 1.00 79.71 ? 441 ARG A NH2 1 ATOM 1956 N N . GLU A 1 257 ? -44.927 1.051 81.227 1.00 78.88 ? 442 GLU A N 1 ATOM 1957 C CA . GLU A 1 257 ? -45.462 0.795 82.561 1.00 79.00 ? 442 GLU A CA 1 ATOM 1958 C C . GLU A 1 257 ? -46.903 0.306 82.462 1.00 78.60 ? 442 GLU A C 1 ATOM 1959 O O . GLU A 1 257 ? -47.732 0.927 81.793 1.00 78.13 ? 442 GLU A O 1 ATOM 1960 C CB . GLU A 1 257 ? -45.394 2.052 83.429 1.00 79.47 ? 442 GLU A CB 1 ATOM 1961 C CG . GLU A 1 257 ? -43.973 2.479 83.783 1.00 80.19 ? 442 GLU A CG 1 ATOM 1962 C CD . GLU A 1 257 ? -43.918 3.496 84.916 1.00 80.64 ? 442 GLU A CD 1 ATOM 1963 O OE1 . GLU A 1 257 ? -44.716 3.383 85.874 1.00 81.31 ? 442 GLU A OE1 1 ATOM 1964 O OE2 . GLU A 1 257 ? -43.065 4.406 84.853 1.00 81.32 ? 442 GLU A OE2 1 ATOM 1965 N N . VAL A 1 258 ? -47.186 -0.816 83.121 1.00 78.37 ? 443 VAL A N 1 ATOM 1966 C CA . VAL A 1 258 ? -48.532 -1.376 83.181 1.00 78.12 ? 443 VAL A CA 1 ATOM 1967 C C . VAL A 1 258 ? -48.955 -1.505 84.637 1.00 78.04 ? 443 VAL A C 1 ATOM 1968 O O . VAL A 1 258 ? -48.374 -2.289 85.386 1.00 77.86 ? 443 VAL A O 1 ATOM 1969 C CB . VAL A 1 258 ? -48.593 -2.766 82.522 1.00 78.13 ? 443 VAL A CB 1 ATOM 1970 C CG1 . VAL A 1 258 ? -49.972 -3.386 82.708 1.00 77.96 ? 443 VAL A CG1 1 ATOM 1971 C CG2 . VAL A 1 258 ? -48.243 -2.669 81.046 1.00 78.38 ? 443 VAL A CG2 1 ATOM 1972 N N . THR A 1 259 ? -49.965 -0.732 85.031 1.00 77.92 ? 444 THR A N 1 ATOM 1973 C CA . THR A 1 259 ? -50.468 -0.746 86.401 1.00 77.52 ? 444 THR A CA 1 ATOM 1974 C C . THR A 1 259 ? -51.632 -1.720 86.535 1.00 77.63 ? 444 THR A C 1 ATOM 1975 O O . THR A 1 259 ? -52.571 -1.685 85.741 1.00 78.35 ? 444 THR A O 1 ATOM 1976 C CB . THR A 1 259 ? -50.945 0.652 86.835 1.00 77.18 ? 444 THR A CB 1 ATOM 1977 O OG1 . THR A 1 259 ? -49.848 1.572 86.788 1.00 77.05 ? 444 THR A OG1 1 ATOM 1978 C CG2 . THR A 1 259 ? -51.511 0.614 88.247 1.00 77.57 ? 444 THR A CG2 1 ATOM 1979 N N . VAL A 1 260 ? -51.564 -2.584 87.544 1.00 77.51 ? 445 VAL A N 1 ATOM 1980 C CA . VAL A 1 260 ? -52.677 -3.462 87.893 1.00 77.49 ? 445 VAL A CA 1 ATOM 1981 C C . VAL A 1 260 ? -53.289 -2.995 89.213 1.00 77.82 ? 445 VAL A C 1 ATOM 1982 O O . VAL A 1 260 ? -52.595 -2.905 90.227 1.00 77.93 ? 445 VAL A O 1 ATOM 1983 C CB . VAL A 1 260 ? -52.218 -4.926 88.027 1.00 76.37 ? 445 VAL A CB 1 ATOM 1984 C CG1 . VAL A 1 260 ? -53.385 -5.818 88.432 1.00 76.35 ? 445 VAL A CG1 1 ATOM 1985 C CG2 . VAL A 1 260 ? -51.601 -5.410 86.724 1.00 75.25 ? 445 VAL A CG2 1 ATOM 1986 N N . ASN A 1 261 ? -54.586 -2.688 89.187 1.00 78.09 ? 446 ASN A N 1 ATOM 1987 C CA . ASN A 1 261 ? -55.313 -2.221 90.368 1.00 78.30 ? 446 ASN A CA 1 ATOM 1988 C C . ASN A 1 261 ? -56.348 -3.255 90.801 1.00 78.53 ? 446 ASN A C 1 ATOM 1989 O O . ASN A 1 261 ? -57.255 -3.583 90.039 1.00 78.52 ? 446 ASN A O 1 ATOM 1990 C CB . ASN A 1 261 ? -56.013 -0.894 90.068 1.00 78.11 ? 446 ASN A CB 1 ATOM 1991 C CG . ASN A 1 261 ? -55.051 0.183 89.599 1.00 78.50 ? 446 ASN A CG 1 ATOM 1992 O OD1 . ASN A 1 261 ? -54.236 0.683 90.373 1.00 78.84 ? 446 ASN A OD1 1 ATOM 1993 N ND2 . ASN A 1 261 ? -55.149 0.551 88.323 1.00 78.48 ? 446 ASN A ND2 1 ATOM 1994 N N . VAL A 1 262 ? -56.213 -3.762 92.023 1.00 79.34 ? 447 VAL A N 1 ATOM 1995 C CA . VAL A 1 262 ? -57.148 -4.753 92.549 1.00 80.14 ? 447 VAL A CA 1 ATOM 1996 C C . VAL A 1 262 ? -58.236 -4.076 93.378 1.00 80.41 ? 447 VAL A C 1 ATOM 1997 O O . VAL A 1 262 ? -57.949 -3.474 94.410 1.00 80.52 ? 447 VAL A O 1 ATOM 1998 C CB . VAL A 1 262 ? -56.431 -5.804 93.418 1.00 80.76 ? 447 VAL A CB 1 ATOM 1999 C CG1 . VAL A 1 262 ? -57.436 -6.787 94.007 1.00 80.83 ? 447 VAL A CG1 1 ATOM 2000 C CG2 . VAL A 1 262 ? -55.379 -6.541 92.599 1.00 81.05 ? 447 VAL A CG2 1 ATOM 2001 N N . LEU A 1 263 ? -59.480 -4.173 92.914 1.00 81.23 ? 448 LEU A N 1 ATOM 2002 C CA . LEU A 1 263 ? -60.631 -3.678 93.665 1.00 82.01 ? 448 LEU A CA 1 ATOM 2003 C C . LEU A 1 263 ? -61.047 -4.713 94.705 1.00 82.70 ? 448 LEU A C 1 ATOM 2004 O O . LEU A 1 263 ? -61.359 -5.853 94.362 1.00 82.33 ? 448 LEU A O 1 ATOM 2005 C CB . LEU A 1 263 ? -61.811 -3.394 92.731 1.00 81.10 ? 448 LEU A CB 1 ATOM 2006 C CG . LEU A 1 263 ? -61.639 -2.262 91.717 1.00 80.72 ? 448 LEU A CG 1 ATOM 2007 C CD1 . LEU A 1 263 ? -62.775 -2.284 90.707 1.00 80.83 ? 448 LEU A CD1 1 ATOM 2008 C CD2 . LEU A 1 263 ? -61.566 -0.913 92.414 1.00 80.44 ? 448 LEU A CD2 1 ATOM 2009 N N . SER A 1 264 ? -61.045 -4.312 95.973 1.00 84.05 ? 449 SER A N 1 ATOM 2010 C CA . SER A 1 264 ? -61.499 -5.183 97.053 1.00 85.16 ? 449 SER A CA 1 ATOM 2011 C C . SER A 1 264 ? -63.014 -5.365 96.962 1.00 86.38 ? 449 SER A C 1 ATOM 2012 O O . SER A 1 264 ? -63.719 -4.457 96.520 1.00 86.88 ? 449 SER A O 1 ATOM 2013 C CB . SER A 1 264 ? -61.118 -4.595 98.415 1.00 86.04 ? 449 SER A CB 1 ATOM 2014 O OG . SER A 1 264 ? -61.679 -3.306 98.589 1.00 86.51 ? 449 SER A OG 1 ATOM 2015 N N . PRO A 1 265 ? -63.520 -6.542 97.378 1.00 87.08 ? 450 PRO A N 1 ATOM 2016 C CA . PRO A 1 265 ? -64.949 -6.838 97.260 1.00 86.89 ? 450 PRO A CA 1 ATOM 2017 C C . PRO A 1 265 ? -65.796 -6.124 98.316 1.00 87.52 ? 450 PRO A C 1 ATOM 2018 O O . PRO A 1 265 ? -65.278 -5.526 99.261 0.50 87.63 ? 450 PRO A O 1 ATOM 2019 C CB . PRO A 1 265 ? -65.003 -8.353 97.465 1.00 87.26 ? 450 PRO A CB 1 ATOM 2020 C CG . PRO A 1 265 ? -63.857 -8.643 98.361 1.00 87.46 ? 450 PRO A CG 1 ATOM 2021 C CD . PRO A 1 265 ? -62.777 -7.661 97.988 1.00 87.44 ? 450 PRO A CD 1 ATOM 2022 O OXT . PRO A 1 265 ? -67.026 -6.129 98.245 0.50 87.57 ? 450 PRO A OXT 1 ATOM 2023 N N . ASP B 2 1 ? -66.926 0.994 82.210 1.00 78.13 ? 1 ASP L N 1 ATOM 2024 C CA . ASP B 2 1 ? -66.287 1.130 80.870 1.00 78.05 ? 1 ASP L CA 1 ATOM 2025 C C . ASP B 2 1 ? -66.344 2.577 80.386 1.00 77.66 ? 1 ASP L C 1 ATOM 2026 O O . ASP B 2 1 ? -67.202 3.349 80.821 1.00 77.69 ? 1 ASP L O 1 ATOM 2027 C CB . ASP B 2 1 ? -66.970 0.204 79.857 1.00 79.05 ? 1 ASP L CB 1 ATOM 2028 C CG . ASP B 2 1 ? -68.440 0.535 79.653 1.00 80.30 ? 1 ASP L CG 1 ATOM 2029 O OD1 . ASP B 2 1 ? -68.936 0.336 78.523 1.00 80.89 ? 1 ASP L OD1 1 ATOM 2030 O OD2 . ASP B 2 1 ? -69.097 0.993 80.617 1.00 80.49 ? 1 ASP L OD2 1 ATOM 2031 N N . ILE B 2 2 ? -65.432 2.938 79.486 1.00 77.38 ? 2 ILE L N 1 ATOM 2032 C CA . ILE B 2 2 ? -65.371 4.300 78.959 1.00 77.50 ? 2 ILE L CA 1 ATOM 2033 C C . ILE B 2 2 ? -66.416 4.486 77.865 1.00 76.55 ? 2 ILE L C 1 ATOM 2034 O O . ILE B 2 2 ? -66.417 3.768 76.869 1.00 75.55 ? 2 ILE L O 1 ATOM 2035 C CB . ILE B 2 2 ? -63.977 4.642 78.398 1.00 77.83 ? 2 ILE L CB 1 ATOM 2036 C CG1 . ILE B 2 2 ? -62.917 4.520 79.496 1.00 78.09 ? 2 ILE L CG1 1 ATOM 2037 C CG2 . ILE B 2 2 ? -63.971 6.052 77.818 1.00 77.60 ? 2 ILE L CG2 1 ATOM 2038 C CD1 . ILE B 2 2 ? -61.521 4.895 79.045 1.00 78.07 ? 2 ILE L CD1 1 ATOM 2039 N N . LEU B 2 3 ? -67.299 5.460 78.065 1.00 77.16 ? 3 LEU L N 1 ATOM 2040 C CA . LEU B 2 3 ? -68.403 5.727 77.153 1.00 77.22 ? 3 LEU L CA 1 ATOM 2041 C C . LEU B 2 3 ? -68.036 6.885 76.226 1.00 77.65 ? 3 LEU L C 1 ATOM 2042 O O . LEU B 2 3 ? -67.579 7.930 76.685 1.00 78.71 ? 3 LEU L O 1 ATOM 2043 C CB . LEU B 2 3 ? -69.654 6.072 77.962 1.00 77.30 ? 3 LEU L CB 1 ATOM 2044 C CG . LEU B 2 3 ? -70.998 6.184 77.244 1.00 77.42 ? 3 LEU L CG 1 ATOM 2045 C CD1 . LEU B 2 3 ? -71.398 4.858 76.615 1.00 77.77 ? 3 LEU L CD1 1 ATOM 2046 C CD2 . LEU B 2 3 ? -72.057 6.653 78.232 1.00 77.02 ? 3 LEU L CD2 1 ATOM 2047 N N . LEU B 2 4 ? -68.223 6.685 74.923 1.00 77.30 ? 4 LEU L N 1 ATOM 2048 C CA . LEU B 2 4 ? -67.939 7.709 73.923 1.00 77.14 ? 4 LEU L CA 1 ATOM 2049 C C . LEU B 2 4 ? -69.234 8.140 73.257 1.00 77.34 ? 4 LEU L C 1 ATOM 2050 O O . LEU B 2 4 ? -69.939 7.314 72.679 1.00 77.54 ? 4 LEU L O 1 ATOM 2051 C CB . LEU B 2 4 ? -66.984 7.164 72.865 1.00 78.20 ? 4 LEU L CB 1 ATOM 2052 C CG . LEU B 2 4 ? -65.575 6.827 73.348 1.00 79.03 ? 4 LEU L CG 1 ATOM 2053 C CD1 . LEU B 2 4 ? -64.866 5.947 72.342 1.00 78.82 ? 4 LEU L CD1 1 ATOM 2054 C CD2 . LEU B 2 4 ? -64.784 8.099 73.603 1.00 80.08 ? 4 LEU L CD2 1 ATOM 2055 N N . THR B 2 5 ? -69.543 9.433 73.343 1.00 77.43 ? 5 THR L N 1 ATOM 2056 C CA . THR B 2 5 ? -70.752 9.993 72.744 1.00 76.82 ? 5 THR L CA 1 ATOM 2057 C C . THR B 2 5 ? -70.384 10.934 71.597 1.00 76.00 ? 5 THR L C 1 ATOM 2058 O O . THR B 2 5 ? -69.702 11.939 71.807 1.00 75.60 ? 5 THR L O 1 ATOM 2059 C CB . THR B 2 5 ? -71.582 10.766 73.789 1.00 77.70 ? 5 THR L CB 1 ATOM 2060 O OG1 . THR B 2 5 ? -71.897 9.901 74.888 1.00 78.22 ? 5 THR L OG1 1 ATOM 2061 C CG2 . THR B 2 5 ? -72.876 11.292 73.177 1.00 77.63 ? 5 THR L CG2 1 ATOM 2062 N N . GLN B 2 6 ? -70.844 10.599 70.391 1.00 75.80 ? 6 GLN L N 1 ATOM 2063 C CA . GLN B 2 6 ? -70.548 11.388 69.191 1.00 75.82 ? 6 GLN L CA 1 ATOM 2064 C C . GLN B 2 6 ? -71.687 12.332 68.840 1.00 74.74 ? 6 GLN L C 1 ATOM 2065 O O . GLN B 2 6 ? -72.847 12.055 69.138 1.00 74.67 ? 6 GLN L O 1 ATOM 2066 C CB . GLN B 2 6 ? -70.280 10.472 67.998 1.00 75.69 ? 6 GLN L CB 1 ATOM 2067 C CG . GLN B 2 6 ? -68.904 9.854 67.994 1.00 76.02 ? 6 GLN L CG 1 ATOM 2068 C CD . GLN B 2 6 ? -68.654 9.020 66.757 1.00 76.60 ? 6 GLN L CD 1 ATOM 2069 O OE1 . GLN B 2 6 ? -68.784 7.797 66.787 1.00 77.96 ? 6 GLN L OE1 1 ATOM 2070 N NE2 . GLN B 2 6 ? -68.307 9.678 65.656 1.00 76.13 ? 6 GLN L NE2 1 ATOM 2071 N N . SER B 2 7 ? -71.346 13.438 68.185 1.00 74.58 ? 7 SER L N 1 ATOM 2072 C CA . SER B 2 7 ? -72.341 14.413 67.751 1.00 75.26 ? 7 SER L CA 1 ATOM 2073 C C . SER B 2 7 ? -71.847 15.224 66.549 1.00 75.33 ? 7 SER L C 1 ATOM 2074 O O . SER B 2 7 ? -70.658 15.538 66.461 1.00 75.06 ? 7 SER L O 1 ATOM 2075 C CB . SER B 2 7 ? -72.695 15.356 68.901 1.00 75.23 ? 7 SER L CB 1 ATOM 2076 O OG . SER B 2 7 ? -71.542 16.000 69.405 1.00 75.28 ? 7 SER L OG 1 ATOM 2077 N N . PRO B 2 8 ? -72.755 15.554 65.608 1.00 75.51 ? 8 PRO L N 1 ATOM 2078 C CA . PRO B 2 8 ? -74.156 15.138 65.572 1.00 75.79 ? 8 PRO L CA 1 ATOM 2079 C C . PRO B 2 8 ? -74.303 13.729 65.004 1.00 76.19 ? 8 PRO L C 1 ATOM 2080 O O . PRO B 2 8 ? -73.308 13.112 64.621 1.00 76.60 ? 8 PRO L O 1 ATOM 2081 C CB . PRO B 2 8 ? -74.813 16.167 64.634 1.00 75.82 ? 8 PRO L CB 1 ATOM 2082 C CG . PRO B 2 8 ? -73.706 17.086 64.165 1.00 75.82 ? 8 PRO L CG 1 ATOM 2083 C CD . PRO B 2 8 ? -72.421 16.404 64.456 1.00 75.69 ? 8 PRO L CD 1 ATOM 2084 N N . ALA B 2 9 ? -75.534 13.227 64.955 1.00 76.01 ? 9 ALA L N 1 ATOM 2085 C CA . ALA B 2 9 ? -75.811 11.928 64.345 1.00 75.98 ? 9 ALA L CA 1 ATOM 2086 C C . ALA B 2 9 ? -75.698 12.023 62.826 1.00 75.91 ? 9 ALA L C 1 ATOM 2087 O O . ALA B 2 9 ? -75.058 11.187 62.191 1.00 75.69 ? 9 ALA L O 1 ATOM 2088 C CB . ALA B 2 9 ? -77.192 11.440 64.742 1.00 75.59 ? 9 ALA L CB 1 ATOM 2089 N N . ILE B 2 10 ? -76.325 13.048 62.256 1.00 76.58 ? 10 ILE L N 1 ATOM 2090 C CA . ILE B 2 10 ? -76.322 13.271 60.811 1.00 76.99 ? 10 ILE L CA 1 ATOM 2091 C C . ILE B 2 10 ? -75.657 14.610 60.510 1.00 77.39 ? 10 ILE L C 1 ATOM 2092 O O . ILE B 2 10 ? -75.877 15.591 61.220 1.00 78.26 ? 10 ILE L O 1 ATOM 2093 C CB . ILE B 2 10 ? -77.755 13.273 60.244 1.00 77.21 ? 10 ILE L CB 1 ATOM 2094 C CG1 . ILE B 2 10 ? -78.449 11.934 60.535 1.00 77.68 ? 10 ILE L CG1 1 ATOM 2095 C CG2 . ILE B 2 10 ? -77.733 13.544 58.744 1.00 76.82 ? 10 ILE L CG2 1 ATOM 2096 C CD1 . ILE B 2 10 ? -79.966 11.997 60.456 1.00 77.73 ? 10 ILE L CD1 1 ATOM 2097 N N . LEU B 2 11 ? -74.859 14.646 59.448 1.00 77.05 ? 11 LEU L N 1 ATOM 2098 C CA . LEU B 2 11 ? -74.010 15.797 59.158 1.00 77.15 ? 11 LEU L CA 1 ATOM 2099 C C . LEU B 2 11 ? -74.080 16.182 57.678 1.00 77.02 ? 11 LEU L C 1 ATOM 2100 O O . LEU B 2 11 ? -73.142 15.954 56.917 1.00 77.40 ? 11 LEU L O 1 ATOM 2101 C CB . LEU B 2 11 ? -72.574 15.469 59.580 1.00 77.26 ? 11 LEU L CB 1 ATOM 2102 C CG . LEU B 2 11 ? -71.545 16.595 59.663 1.00 77.02 ? 11 LEU L CG 1 ATOM 2103 C CD1 . LEU B 2 11 ? -72.070 17.788 60.453 1.00 76.76 ? 11 LEU L CD1 1 ATOM 2104 C CD2 . LEU B 2 11 ? -70.266 16.053 60.289 1.00 76.87 ? 11 LEU L CD2 1 ATOM 2105 N N . SER B 2 12 ? -75.205 16.774 57.284 1.00 77.30 ? 12 SER L N 1 ATOM 2106 C CA . SER B 2 12 ? -75.445 17.163 55.892 1.00 77.91 ? 12 SER L CA 1 ATOM 2107 C C . SER B 2 12 ? -74.642 18.411 55.523 1.00 78.00 ? 12 SER L C 1 ATOM 2108 O O . SER B 2 12 ? -74.740 19.439 56.194 1.00 78.55 ? 12 SER L O 1 ATOM 2109 C CB . SER B 2 12 ? -76.940 17.418 55.667 1.00 79.35 ? 12 SER L CB 1 ATOM 2110 O OG . SER B 2 12 ? -77.214 17.730 54.311 1.00 80.40 ? 12 SER L OG 1 ATOM 2111 N N . VAL B 2 13 ? -73.861 18.320 54.446 1.00 77.76 ? 13 VAL L N 1 ATOM 2112 C CA . VAL B 2 13 ? -72.926 19.384 54.078 1.00 77.75 ? 13 VAL L CA 1 ATOM 2113 C C . VAL B 2 13 ? -72.585 19.365 52.581 1.00 77.46 ? 13 VAL L C 1 ATOM 2114 O O . VAL B 2 13 ? -72.541 18.306 51.959 1.00 77.03 ? 13 VAL L O 1 ATOM 2115 C CB . VAL B 2 13 ? -71.626 19.266 54.905 1.00 77.61 ? 13 VAL L CB 1 ATOM 2116 C CG1 . VAL B 2 13 ? -70.892 17.974 54.571 1.00 77.51 ? 13 VAL L CG1 1 ATOM 2117 C CG2 . VAL B 2 13 ? -70.732 20.469 54.677 1.00 77.78 ? 13 VAL L CG2 1 ATOM 2118 N N . SER B 2 14 ? -72.345 20.545 52.014 1.00 77.83 ? 14 SER L N 1 ATOM 2119 C CA . SER B 2 14 ? -72.018 20.678 50.593 1.00 78.17 ? 14 SER L CA 1 ATOM 2120 C C . SER B 2 14 ? -70.522 20.437 50.366 1.00 78.17 ? 14 SER L C 1 ATOM 2121 O O . SER B 2 14 ? -69.723 20.633 51.284 1.00 78.24 ? 14 SER L O 1 ATOM 2122 C CB . SER B 2 14 ? -72.409 22.074 50.096 1.00 78.46 ? 14 SER L CB 1 ATOM 2123 O OG . SER B 2 14 ? -72.547 22.108 48.688 1.00 79.04 ? 14 SER L OG 1 ATOM 2124 N N . PRO B 2 15 ? -70.135 19.994 49.150 1.00 78.37 ? 15 PRO L N 1 ATOM 2125 C CA . PRO B 2 15 ? -68.713 19.781 48.864 1.00 78.70 ? 15 PRO L CA 1 ATOM 2126 C C . PRO B 2 15 ? -67.897 21.069 48.911 1.00 78.78 ? 15 PRO L C 1 ATOM 2127 O O . PRO B 2 15 ? -68.357 22.109 48.440 1.00 78.38 ? 15 PRO L O 1 ATOM 2128 C CB . PRO B 2 15 ? -68.717 19.208 47.439 1.00 78.45 ? 15 PRO L CB 1 ATOM 2129 C CG . PRO B 2 15 ? -70.098 18.724 47.213 1.00 78.48 ? 15 PRO L CG 1 ATOM 2130 C CD . PRO B 2 15 ? -70.975 19.635 47.994 1.00 78.44 ? 15 PRO L CD 1 ATOM 2131 N N . GLY B 2 16 ? -66.695 20.985 49.479 1.00 79.61 ? 16 GLY L N 1 ATOM 2132 C CA . GLY B 2 16 ? -65.812 22.144 49.620 1.00 80.38 ? 16 GLY L CA 1 ATOM 2133 C C . GLY B 2 16 ? -65.814 22.751 51.015 1.00 81.17 ? 16 GLY L C 1 ATOM 2134 O O . GLY B 2 16 ? -64.900 23.500 51.369 1.00 81.15 ? 16 GLY L O 1 ATOM 2135 N N . GLU B 2 17 ? -66.838 22.433 51.807 1.00 81.60 ? 17 GLU L N 1 ATOM 2136 C CA . GLU B 2 17 ? -66.970 22.976 53.160 1.00 81.64 ? 17 GLU L CA 1 ATOM 2137 C C . GLU B 2 17 ? -66.017 22.291 54.136 1.00 81.48 ? 17 GLU L C 1 ATOM 2138 O O . GLU B 2 17 ? -65.496 21.207 53.858 1.00 81.09 ? 17 GLU L O 1 ATOM 2139 C CB . GLU B 2 17 ? -68.409 22.824 53.667 1.00 81.91 ? 17 GLU L CB 1 ATOM 2140 C CG . GLU B 2 17 ? -69.439 23.671 52.922 1.00 82.30 ? 17 GLU L CG 1 ATOM 2141 C CD . GLU B 2 17 ? -70.824 23.618 53.560 1.00 82.52 ? 17 GLU L CD 1 ATOM 2142 O OE1 . GLU B 2 17 ? -71.827 23.610 52.814 1.00 82.81 ? 17 GLU L OE1 1 ATOM 2143 O OE2 . GLU B 2 17 ? -70.914 23.582 54.805 1.00 83.01 ? 17 GLU L OE2 1 ATOM 2144 N N . ARG B 2 18 ? -65.802 22.940 55.278 1.00 81.78 ? 18 ARG L N 1 ATOM 2145 C CA . ARG B 2 18 ? -64.997 22.384 56.363 1.00 81.82 ? 18 ARG L CA 1 ATOM 2146 C C . ARG B 2 18 ? -65.917 21.768 57.422 1.00 81.90 ? 18 ARG L C 1 ATOM 2147 O O . ARG B 2 18 ? -66.553 22.487 58.195 1.00 81.97 ? 18 ARG L O 1 ATOM 2148 C CB . ARG B 2 18 ? -64.124 23.478 56.985 1.00 82.26 ? 18 ARG L CB 1 ATOM 2149 C CG . ARG B 2 18 ? -63.046 22.964 57.932 1.00 82.30 ? 18 ARG L CG 1 ATOM 2150 C CD . ARG B 2 18 ? -62.463 24.095 58.765 1.00 82.52 ? 18 ARG L CD 1 ATOM 2151 N NE . ARG B 2 18 ? -61.259 23.686 59.491 1.00 82.90 ? 18 ARG L NE 1 ATOM 2152 C CZ . ARG B 2 18 ? -60.027 23.653 58.978 1.00 83.39 ? 18 ARG L CZ 1 ATOM 2153 N NH1 . ARG B 2 18 ? -59.803 23.999 57.710 1.00 83.38 ? 18 ARG L NH1 1 ATOM 2154 N NH2 . ARG B 2 18 ? -59.007 23.266 59.739 1.00 83.20 ? 18 ARG L NH2 1 ATOM 2155 N N . VAL B 2 19 ? -65.986 20.438 57.446 1.00 81.38 ? 19 VAL L N 1 ATOM 2156 C CA . VAL B 2 19 ? -66.854 19.720 58.381 1.00 80.96 ? 19 VAL L CA 1 ATOM 2157 C C . VAL B 2 19 ? -66.060 19.230 59.597 1.00 80.23 ? 19 VAL L C 1 ATOM 2158 O O . VAL B 2 19 ? -64.851 19.023 59.506 1.00 80.00 ? 19 VAL L O 1 ATOM 2159 C CB . VAL B 2 19 ? -67.545 18.525 57.684 1.00 81.62 ? 19 VAL L CB 1 ATOM 2160 C CG1 . VAL B 2 19 ? -66.588 17.345 57.548 1.00 82.13 ? 19 VAL L CG1 1 ATOM 2161 C CG2 . VAL B 2 19 ? -68.792 18.116 58.440 1.00 81.46 ? 19 VAL L CG2 1 ATOM 2162 N N . SER B 2 20 ? -66.745 19.050 60.728 1.00 80.29 ? 20 SER L N 1 ATOM 2163 C CA . SER B 2 20 ? -66.102 18.599 61.970 1.00 80.45 ? 20 SER L CA 1 ATOM 2164 C C . SER B 2 20 ? -66.971 17.620 62.768 1.00 79.69 ? 20 SER L C 1 ATOM 2165 O O . SER B 2 20 ? -68.152 17.878 63.005 1.00 79.01 ? 20 SER L O 1 ATOM 2166 C CB . SER B 2 20 ? -65.749 19.798 62.851 1.00 80.80 ? 20 SER L CB 1 ATOM 2167 O OG . SER B 2 20 ? -64.665 20.525 62.303 1.00 81.37 ? 20 SER L OG 1 ATOM 2168 N N . PHE B 2 21 ? -66.368 16.507 63.184 1.00 79.87 ? 21 PHE L N 1 ATOM 2169 C CA . PHE B 2 21 ? -67.045 15.493 63.995 1.00 80.64 ? 21 PHE L CA 1 ATOM 2170 C C . PHE B 2 21 ? -66.606 15.630 65.448 1.00 80.27 ? 21 PHE L C 1 ATOM 2171 O O . PHE B 2 21 ? -65.417 15.777 65.719 1.00 79.81 ? 21 PHE L O 1 ATOM 2172 C CB . PHE B 2 21 ? -66.690 14.085 63.510 1.00 81.68 ? 21 PHE L CB 1 ATOM 2173 C CG . PHE B 2 21 ? -66.889 13.871 62.038 1.00 81.56 ? 21 PHE L CG 1 ATOM 2174 C CD1 . PHE B 2 21 ? -68.094 13.397 61.553 1.00 81.75 ? 21 PHE L CD1 1 ATOM 2175 C CD2 . PHE B 2 21 ? -65.860 14.119 61.140 1.00 82.17 ? 21 PHE L CD2 1 ATOM 2176 C CE1 . PHE B 2 21 ? -68.282 13.185 60.193 1.00 81.87 ? 21 PHE L CE1 1 ATOM 2177 C CE2 . PHE B 2 21 ? -66.039 13.912 59.776 1.00 82.12 ? 21 PHE L CE2 1 ATOM 2178 C CZ . PHE B 2 21 ? -67.253 13.443 59.304 1.00 81.93 ? 21 PHE L CZ 1 ATOM 2179 N N . SER B 2 22 ? -67.559 15.553 66.375 1.00 80.73 ? 22 SER L N 1 ATOM 2180 C CA . SER B 2 22 ? -67.268 15.650 67.811 1.00 81.13 ? 22 SER L CA 1 ATOM 2181 C C . SER B 2 22 ? -67.390 14.284 68.501 1.00 81.75 ? 22 SER L C 1 ATOM 2182 O O . SER B 2 22 ? -68.285 13.502 68.186 1.00 82.29 ? 22 SER L O 1 ATOM 2183 C CB . SER B 2 22 ? -68.217 16.656 68.469 1.00 81.23 ? 22 SER L CB 1 ATOM 2184 O OG . SER B 2 22 ? -67.987 16.753 69.863 1.00 81.62 ? 22 SER L OG 1 ATOM 2185 N N . CYS B 2 23 ? -66.481 14.010 69.437 1.00 82.18 ? 23 CYS L N 1 ATOM 2186 C CA . CYS B 2 23 ? -66.516 12.784 70.244 1.00 81.63 ? 23 CYS L CA 1 ATOM 2187 C C . CYS B 2 23 ? -66.093 13.099 71.682 1.00 81.36 ? 23 CYS L C 1 ATOM 2188 O O . CYS B 2 23 ? -64.934 13.434 71.931 1.00 80.98 ? 23 CYS L O 1 ATOM 2189 C CB . CYS B 2 23 ? -65.599 11.713 69.636 1.00 82.31 ? 23 CYS L CB 1 ATOM 2190 S SG . CYS B 2 23 ? -65.395 10.195 70.639 1.00 83.43 ? 23 CYS L SG 1 ATOM 2191 N N . ARG B 2 24 ? -67.039 12.999 72.617 1.00 81.48 ? 24 ARG L N 1 ATOM 2192 C CA . ARG B 2 24 ? -66.781 13.279 74.034 1.00 81.19 ? 24 ARG L CA 1 ATOM 2193 C C . ARG B 2 24 ? -66.636 11.980 74.826 1.00 80.48 ? 24 ARG L C 1 ATOM 2194 O O . ARG B 2 24 ? -67.412 11.045 74.640 1.00 80.70 ? 24 ARG L O 1 ATOM 2195 C CB . ARG B 2 24 ? -67.919 14.110 74.630 1.00 81.45 ? 24 ARG L CB 1 ATOM 2196 C CG . ARG B 2 24 ? -67.659 14.581 76.058 1.00 81.87 ? 24 ARG L CG 1 ATOM 2197 C CD . ARG B 2 24 ? -68.921 15.091 76.733 1.00 82.64 ? 24 ARG L CD 1 ATOM 2198 N NE . ARG B 2 24 ? -69.438 16.304 76.104 1.00 83.29 ? 24 ARG L NE 1 ATOM 2199 C CZ . ARG B 2 24 ? -70.420 17.054 76.602 1.00 83.84 ? 24 ARG L CZ 1 ATOM 2200 N NH1 . ARG B 2 24 ? -71.010 16.732 77.751 1.00 84.04 ? 24 ARG L NH1 1 ATOM 2201 N NH2 . ARG B 2 24 ? -70.814 18.140 75.947 1.00 83.92 ? 24 ARG L NH2 1 ATOM 2202 N N . ALA B 2 25 ? -65.652 11.941 75.723 1.00 80.03 ? 25 ALA L N 1 ATOM 2203 C CA . ALA B 2 25 ? -65.403 10.765 76.560 1.00 79.83 ? 25 ALA L CA 1 ATOM 2204 C C . ALA B 2 25 ? -65.965 10.974 77.965 1.00 79.65 ? 25 ALA L C 1 ATOM 2205 O O . ALA B 2 25 ? -65.985 12.097 78.472 1.00 79.81 ? 25 ALA L O 1 ATOM 2206 C CB . ALA B 2 25 ? -63.915 10.476 76.628 1.00 79.28 ? 25 ALA L CB 1 ATOM 2207 N N . SER B 2 26 ? -66.413 9.886 78.588 1.00 79.02 ? 26 SER L N 1 ATOM 2208 C CA . SER B 2 26 ? -66.982 9.941 79.936 1.00 78.80 ? 26 SER L CA 1 ATOM 2209 C C . SER B 2 26 ? -65.901 10.154 80.996 1.00 78.69 ? 26 SER L C 1 ATOM 2210 O O . SER B 2 26 ? -66.139 10.824 82.003 1.00 79.09 ? 26 SER L O 1 ATOM 2211 C CB . SER B 2 26 ? -67.770 8.665 80.240 1.00 77.80 ? 26 SER L CB 1 ATOM 2212 O OG . SER B 2 26 ? -66.957 7.514 80.109 1.00 77.29 ? 26 SER L OG 1 ATOM 2213 N N . GLN B 2 27 ? -64.727 9.570 80.766 1.00 78.71 ? 27 GLN L N 1 ATOM 2214 C CA . GLN B 2 27 ? -63.549 9.795 81.608 1.00 79.24 ? 27 GLN L CA 1 ATOM 2215 C C . GLN B 2 27 ? -62.520 10.617 80.836 1.00 79.35 ? 27 GLN L C 1 ATOM 2216 O O . GLN B 2 27 ? -62.751 10.984 79.685 1.00 80.44 ? 27 GLN L O 1 ATOM 2217 C CB . GLN B 2 27 ? -62.934 8.458 82.030 1.00 79.83 ? 27 GLN L CB 1 ATOM 2218 C CG . GLN B 2 27 ? -63.875 7.561 82.828 1.00 80.78 ? 27 GLN L CG 1 ATOM 2219 C CD . GLN B 2 27 ? -63.223 6.256 83.266 1.00 80.84 ? 27 GLN L CD 1 ATOM 2220 O OE1 . GLN B 2 27 ? -62.032 6.030 83.032 1.00 81.22 ? 27 GLN L OE1 1 ATOM 2221 N NE2 . GLN B 2 27 ? -64.006 5.390 83.907 1.00 80.80 ? 27 GLN L NE2 1 ATOM 2222 N N . SER B 2 28 ? -61.391 10.913 81.475 1.00 78.87 ? 28 SER L N 1 ATOM 2223 C CA . SER B 2 28 ? -60.264 11.549 80.796 1.00 78.49 ? 28 SER L CA 1 ATOM 2224 C C . SER B 2 28 ? -59.295 10.468 80.327 1.00 78.25 ? 28 SER L C 1 ATOM 2225 O O . SER B 2 28 ? -58.763 9.710 81.142 1.00 78.08 ? 28 SER L O 1 ATOM 2226 C CB . SER B 2 28 ? -59.556 12.529 81.730 1.00 78.75 ? 28 SER L CB 1 ATOM 2227 O OG . SER B 2 28 ? -58.569 13.268 81.032 1.00 79.05 ? 28 SER L OG 1 ATOM 2228 N N . ILE B 2 29 ? -59.063 10.408 79.015 1.00 77.94 ? 29 ILE L N 1 ATOM 2229 C CA . ILE B 2 29 ? -58.336 9.289 78.400 1.00 77.44 ? 29 ILE L CA 1 ATOM 2230 C C . ILE B 2 29 ? -57.066 9.714 77.644 1.00 77.05 ? 29 ILE L C 1 ATOM 2231 O O . ILE B 2 29 ? -56.586 8.989 76.768 1.00 76.56 ? 29 ILE L O 1 ATOM 2232 C CB . ILE B 2 29 ? -59.262 8.489 77.448 1.00 77.30 ? 29 ILE L CB 1 ATOM 2233 C CG1 . ILE B 2 29 ? -59.834 9.390 76.348 1.00 77.21 ? 29 ILE L CG1 1 ATOM 2234 C CG2 . ILE B 2 29 ? -60.395 7.854 78.233 1.00 77.43 ? 29 ILE L CG2 1 ATOM 2235 C CD1 . ILE B 2 29 ? -60.524 8.624 75.244 1.00 77.27 ? 29 ILE L CD1 1 ATOM 2236 N N . GLY B 2 30 ? -56.518 10.876 77.997 1.00 76.88 ? 30 GLY L N 1 ATOM 2237 C CA . GLY B 2 30 ? -55.305 11.384 77.361 1.00 76.37 ? 30 GLY L CA 1 ATOM 2238 C C . GLY B 2 30 ? -55.509 11.652 75.882 1.00 75.61 ? 30 GLY L C 1 ATOM 2239 O O . GLY B 2 30 ? -56.325 12.491 75.505 1.00 75.24 ? 30 GLY L O 1 ATOM 2240 N N . THR B 2 31 ? -54.763 10.935 75.045 1.00 75.73 ? 31 THR L N 1 ATOM 2241 C CA . THR B 2 31 ? -54.915 11.025 73.593 1.00 76.25 ? 31 THR L CA 1 ATOM 2242 C C . THR B 2 31 ? -55.126 9.637 72.987 1.00 76.87 ? 31 THR L C 1 ATOM 2243 O O . THR B 2 31 ? -54.790 9.402 71.827 1.00 77.16 ? 31 THR L O 1 ATOM 2244 C CB . THR B 2 31 ? -53.683 11.685 72.936 1.00 76.42 ? 31 THR L CB 1 ATOM 2245 O OG1 . THR B 2 31 ? -52.538 10.838 73.095 1.00 76.77 ? 31 THR L OG1 1 ATOM 2246 C CG2 . THR B 2 31 ? -53.402 13.047 73.560 1.00 76.06 ? 31 THR L CG2 1 ATOM 2247 N N . SER B 2 32 ? -55.699 8.725 73.772 1.00 76.87 ? 32 SER L N 1 ATOM 2248 C CA . SER B 2 32 ? -55.964 7.364 73.314 1.00 76.13 ? 32 SER L CA 1 ATOM 2249 C C . SER B 2 32 ? -57.290 7.316 72.565 1.00 76.26 ? 32 SER L C 1 ATOM 2250 O O . SER B 2 32 ? -58.238 6.669 73.011 1.00 76.03 ? 32 SER L O 1 ATOM 2251 C CB . SER B 2 32 ? -55.995 6.397 74.503 1.00 76.36 ? 32 SER L CB 1 ATOM 2252 O OG . SER B 2 32 ? -54.788 6.451 75.242 1.00 76.89 ? 32 SER L OG 1 ATOM 2253 N N . ILE B 2 33 ? -57.350 8.006 71.427 1.00 76.36 ? 33 ILE L N 1 ATOM 2254 C CA . ILE B 2 33 ? -58.557 8.046 70.600 1.00 75.51 ? 33 ILE L CA 1 ATOM 2255 C C . ILE B 2 33 ? -58.195 7.814 69.132 1.00 74.53 ? 33 ILE L C 1 ATOM 2256 O O . ILE B 2 33 ? -57.145 8.262 68.664 1.00 74.12 ? 33 ILE L O 1 ATOM 2257 C CB . ILE B 2 33 ? -59.307 9.395 70.761 1.00 75.49 ? 33 ILE L CB 1 ATOM 2258 C CG1 . ILE B 2 33 ? -60.808 9.207 70.539 1.00 75.56 ? 33 ILE L CG1 1 ATOM 2259 C CG2 . ILE B 2 33 ? -58.754 10.447 69.818 1.00 75.70 ? 33 ILE L CG2 1 ATOM 2260 C CD1 . ILE B 2 33 ? -61.521 8.602 71.730 1.00 75.48 ? 33 ILE L CD1 1 ATOM 2261 N N . HIS B 2 34 ? -59.060 7.097 68.419 1.00 74.69 ? 34 HIS L N 1 ATOM 2262 C CA . HIS B 2 34 ? -58.824 6.755 67.014 1.00 75.13 ? 34 HIS L CA 1 ATOM 2263 C C . HIS B 2 34 ? -60.105 6.915 66.214 1.00 76.37 ? 34 HIS L C 1 ATOM 2264 O O . HIS B 2 34 ? -61.192 6.625 66.714 1.00 77.61 ? 34 HIS L O 1 ATOM 2265 C CB . HIS B 2 34 ? -58.328 5.313 66.892 1.00 74.18 ? 34 HIS L CB 1 ATOM 2266 C CG . HIS B 2 34 ? -57.288 4.948 67.903 1.00 73.51 ? 34 HIS L CG 1 ATOM 2267 N ND1 . HIS B 2 34 ? -55.940 5.110 67.676 1.00 73.34 ? 34 HIS L ND1 1 ATOM 2268 C CD2 . HIS B 2 34 ? -57.401 4.440 69.153 1.00 73.61 ? 34 HIS L CD2 1 ATOM 2269 C CE1 . HIS B 2 34 ? -55.265 4.715 68.740 1.00 73.64 ? 34 HIS L CE1 1 ATOM 2270 N NE2 . HIS B 2 34 ? -56.128 4.302 69.650 1.00 73.42 ? 34 HIS L NE2 1 ATOM 2271 N N . TRP B 2 35 ? -59.975 7.369 64.970 1.00 76.65 ? 35 TRP L N 1 ATOM 2272 C CA . TRP B 2 35 ? -61.134 7.616 64.110 1.00 75.95 ? 35 TRP L CA 1 ATOM 2273 C C . TRP B 2 35 ? -61.210 6.620 62.954 1.00 75.44 ? 35 TRP L C 1 ATOM 2274 O O . TRP B 2 35 ? -60.194 6.276 62.349 1.00 74.74 ? 35 TRP L O 1 ATOM 2275 C CB . TRP B 2 35 ? -61.094 9.047 63.574 1.00 75.55 ? 35 TRP L CB 1 ATOM 2276 C CG . TRP B 2 35 ? -61.389 10.074 64.622 1.00 75.30 ? 35 TRP L CG 1 ATOM 2277 C CD1 . TRP B 2 35 ? -60.485 10.732 65.401 1.00 75.19 ? 35 TRP L CD1 1 ATOM 2278 C CD2 . TRP B 2 35 ? -62.681 10.553 65.011 1.00 75.08 ? 35 TRP L CD2 1 ATOM 2279 N NE1 . TRP B 2 35 ? -61.133 11.598 66.249 1.00 75.27 ? 35 TRP L NE1 1 ATOM 2280 C CE2 . TRP B 2 35 ? -62.483 11.507 66.029 1.00 75.23 ? 35 TRP L CE2 1 ATOM 2281 C CE3 . TRP B 2 35 ? -63.986 10.275 64.590 1.00 75.22 ? 35 TRP L CE3 1 ATOM 2282 C CZ2 . TRP B 2 35 ? -63.543 12.183 66.637 1.00 75.54 ? 35 TRP L CZ2 1 ATOM 2283 C CZ3 . TRP B 2 35 ? -65.041 10.947 65.196 1.00 75.23 ? 35 TRP L CZ3 1 ATOM 2284 C CH2 . TRP B 2 35 ? -64.812 11.889 66.207 1.00 75.38 ? 35 TRP L CH2 1 ATOM 2285 N N . PHE B 2 36 ? -62.427 6.172 62.652 1.00 76.20 ? 36 PHE L N 1 ATOM 2286 C CA . PHE B 2 36 ? -62.670 5.205 61.583 1.00 76.24 ? 36 PHE L CA 1 ATOM 2287 C C . PHE B 2 36 ? -63.710 5.720 60.605 1.00 75.76 ? 36 PHE L C 1 ATOM 2288 O O . PHE B 2 36 ? -64.659 6.394 61.000 1.00 74.69 ? 36 PHE L O 1 ATOM 2289 C CB . PHE B 2 36 ? -63.157 3.879 62.167 1.00 76.93 ? 36 PHE L CB 1 ATOM 2290 C CG . PHE B 2 36 ? -62.123 3.163 62.971 1.00 77.13 ? 36 PHE L CG 1 ATOM 2291 C CD1 . PHE B 2 36 ? -61.999 3.399 64.333 1.00 77.16 ? 36 PHE L CD1 1 ATOM 2292 C CD2 . PHE B 2 36 ? -61.261 2.262 62.367 1.00 77.01 ? 36 PHE L CD2 1 ATOM 2293 C CE1 . PHE B 2 36 ? -61.036 2.742 65.078 1.00 77.14 ? 36 PHE L CE1 1 ATOM 2294 C CE2 . PHE B 2 36 ? -60.299 1.601 63.104 1.00 76.97 ? 36 PHE L CE2 1 ATOM 2295 C CZ . PHE B 2 36 ? -60.186 1.841 64.463 1.00 77.29 ? 36 PHE L CZ 1 ATOM 2296 N N . GLN B 2 37 ? -63.523 5.387 59.330 1.00 76.41 ? 37 GLN L N 1 ATOM 2297 C CA . GLN B 2 37 ? -64.501 5.673 58.285 1.00 76.29 ? 37 GLN L CA 1 ATOM 2298 C C . GLN B 2 37 ? -65.114 4.359 57.826 1.00 76.04 ? 37 GLN L C 1 ATOM 2299 O O . GLN B 2 37 ? -64.393 3.402 57.548 1.00 76.09 ? 37 GLN L O 1 ATOM 2300 C CB . GLN B 2 37 ? -63.818 6.365 57.105 1.00 76.15 ? 37 GLN L CB 1 ATOM 2301 C CG . GLN B 2 37 ? -64.742 6.715 55.943 1.00 76.33 ? 37 GLN L CG 1 ATOM 2302 C CD . GLN B 2 37 ? -63.982 7.215 54.730 1.00 76.50 ? 37 GLN L CD 1 ATOM 2303 O OE1 . GLN B 2 37 ? -63.032 6.580 54.272 1.00 76.40 ? 37 GLN L OE1 1 ATOM 2304 N NE2 . GLN B 2 37 ? -64.403 8.356 54.197 1.00 77.05 ? 37 GLN L NE2 1 ATOM 2305 N N . GLN B 2 38 ? -66.441 4.308 57.748 1.00 76.57 ? 38 GLN L N 1 ATOM 2306 C CA . GLN B 2 38 ? -67.119 3.134 57.203 1.00 76.86 ? 38 GLN L CA 1 ATOM 2307 C C . GLN B 2 38 ? -68.096 3.512 56.098 1.00 76.16 ? 38 GLN L C 1 ATOM 2308 O O . GLN B 2 38 ? -69.161 4.069 56.358 1.00 75.11 ? 38 GLN L O 1 ATOM 2309 C CB . GLN B 2 38 ? -67.840 2.351 58.300 1.00 76.71 ? 38 GLN L CB 1 ATOM 2310 C CG . GLN B 2 38 ? -68.283 0.960 57.845 1.00 76.61 ? 38 GLN L CG 1 ATOM 2311 C CD . GLN B 2 38 ? -68.892 0.138 58.961 1.00 76.62 ? 38 GLN L CD 1 ATOM 2312 O OE1 . GLN B 2 38 ? -69.540 0.672 59.862 1.00 77.44 ? 38 GLN L OE1 1 ATOM 2313 N NE2 . GLN B 2 38 ? -68.696 -1.175 58.900 1.00 75.50 ? 38 GLN L NE2 1 ATOM 2314 N N . ARG B 2 39 ? -67.715 3.203 54.862 1.00 77.31 ? 39 ARG L N 1 ATOM 2315 C CA . ARG B 2 39 ? -68.618 3.308 53.726 1.00 78.77 ? 39 ARG L CA 1 ATOM 2316 C C . ARG B 2 39 ? -69.587 2.129 53.754 1.00 79.55 ? 39 ARG L C 1 ATOM 2317 O O . ARG B 2 39 ? -69.306 1.097 54.374 1.00 79.67 ? 39 ARG L O 1 ATOM 2318 C CB . ARG B 2 39 ? -67.832 3.310 52.416 1.00 79.35 ? 39 ARG L CB 1 ATOM 2319 C CG . ARG B 2 39 ? -66.778 4.402 52.333 1.00 79.53 ? 39 ARG L CG 1 ATOM 2320 C CD . ARG B 2 39 ? -66.337 4.651 50.903 1.00 79.68 ? 39 ARG L CD 1 ATOM 2321 N NE . ARG B 2 39 ? -65.469 5.825 50.812 1.00 80.23 ? 39 ARG L NE 1 ATOM 2322 C CZ . ARG B 2 39 ? -64.147 5.799 50.624 1.00 80.79 ? 39 ARG L CZ 1 ATOM 2323 N NH1 . ARG B 2 39 ? -63.485 4.651 50.496 1.00 81.10 ? 39 ARG L NH1 1 ATOM 2324 N NH2 . ARG B 2 39 ? -63.477 6.944 50.560 1.00 80.23 ? 39 ARG L NH2 1 ATOM 2325 N N . ILE B 2 40 ? -70.723 2.282 53.082 1.00 79.72 ? 40 ILE L N 1 ATOM 2326 C CA . ILE B 2 40 ? -71.772 1.267 53.120 1.00 80.57 ? 40 ILE L CA 1 ATOM 2327 C C . ILE B 2 40 ? -71.287 -0.054 52.506 1.00 80.67 ? 40 ILE L C 1 ATOM 2328 O O . ILE B 2 40 ? -70.524 -0.055 51.538 1.00 80.61 ? 40 ILE L O 1 ATOM 2329 C CB . ILE B 2 40 ? -73.072 1.764 52.422 1.00 82.84 ? 40 ILE L CB 1 ATOM 2330 C CG1 . ILE B 2 40 ? -74.248 0.822 52.717 1.00 84.28 ? 40 ILE L CG1 1 ATOM 2331 C CG2 . ILE B 2 40 ? -72.861 1.910 50.917 1.00 83.31 ? 40 ILE L CG2 1 ATOM 2332 C CD1 . ILE B 2 40 ? -74.538 0.628 54.203 1.00 84.82 ? 40 ILE L CD1 1 ATOM 2333 N N . ASN B 2 41 ? -71.721 -1.167 53.102 1.00 80.84 ? 41 ASN L N 1 ATOM 2334 C CA . ASN B 2 41 ? -71.286 -2.523 52.719 1.00 80.79 ? 41 ASN L CA 1 ATOM 2335 C C . ASN B 2 41 ? -69.778 -2.779 52.854 1.00 80.83 ? 41 ASN L C 1 ATOM 2336 O O . ASN B 2 41 ? -69.261 -3.749 52.295 1.00 81.51 ? 41 ASN L O 1 ATOM 2337 C CB . ASN B 2 41 ? -71.746 -2.865 51.291 1.00 81.74 ? 41 ASN L CB 1 ATOM 2338 C CG . ASN B 2 41 ? -73.255 -2.851 51.141 1.00 82.38 ? 41 ASN L CG 1 ATOM 2339 O OD1 . ASN B 2 41 ? -73.987 -3.212 52.064 1.00 82.60 ? 41 ASN L OD1 1 ATOM 2340 N ND2 . ASN B 2 41 ? -73.727 -2.445 49.967 1.00 82.50 ? 41 ASN L ND2 1 ATOM 2341 N N . GLY B 2 42 ? -69.085 -1.937 53.620 1.00 80.22 ? 42 GLY L N 1 ATOM 2342 C CA . GLY B 2 42 ? -67.625 -1.997 53.715 1.00 79.60 ? 42 GLY L CA 1 ATOM 2343 C C . GLY B 2 42 ? -67.123 -2.136 55.138 1.00 79.51 ? 42 GLY L C 1 ATOM 2344 O O . GLY B 2 42 ? -67.861 -1.903 56.096 1.00 80.22 ? 42 GLY L O 1 ATOM 2345 N N . SER B 2 43 ? -65.856 -2.517 55.273 1.00 78.86 ? 43 SER L N 1 ATOM 2346 C CA . SER B 2 43 ? -65.219 -2.632 56.581 1.00 77.89 ? 43 SER L CA 1 ATOM 2347 C C . SER B 2 43 ? -64.784 -1.249 57.063 1.00 76.64 ? 43 SER L C 1 ATOM 2348 O O . SER B 2 43 ? -64.552 -0.361 56.246 1.00 76.20 ? 43 SER L O 1 ATOM 2349 C CB . SER B 2 43 ? -64.008 -3.559 56.504 1.00 77.46 ? 43 SER L CB 1 ATOM 2350 O OG . SER B 2 43 ? -64.354 -4.799 55.913 1.00 77.47 ? 43 SER L OG 1 ATOM 2351 N N . PRO B 2 44 ? -64.683 -1.057 58.392 1.00 76.66 ? 44 PRO L N 1 ATOM 2352 C CA . PRO B 2 44 ? -64.160 0.201 58.922 1.00 77.05 ? 44 PRO L CA 1 ATOM 2353 C C . PRO B 2 44 ? -62.714 0.462 58.496 1.00 77.30 ? 44 PRO L C 1 ATOM 2354 O O . PRO B 2 44 ? -61.942 -0.480 58.300 1.00 77.00 ? 44 PRO L O 1 ATOM 2355 C CB . PRO B 2 44 ? -64.247 0.009 60.442 1.00 76.26 ? 44 PRO L CB 1 ATOM 2356 C CG . PRO B 2 44 ? -65.240 -1.062 60.639 1.00 75.73 ? 44 PRO L CG 1 ATOM 2357 C CD . PRO B 2 44 ? -65.073 -1.974 59.475 1.00 76.20 ? 44 PRO L CD 1 ATOM 2358 N N . ARG B 2 45 ? -62.366 1.739 58.368 1.00 77.66 ? 45 ARG L N 1 ATOM 2359 C CA . ARG B 2 45 ? -61.077 2.153 57.822 1.00 77.25 ? 45 ARG L CA 1 ATOM 2360 C C . ARG B 2 45 ? -60.455 3.215 58.720 1.00 76.60 ? 45 ARG L C 1 ATOM 2361 O O . ARG B 2 45 ? -60.980 4.323 58.830 1.00 76.87 ? 45 ARG L O 1 ATOM 2362 C CB . ARG B 2 45 ? -61.283 2.707 56.413 1.00 78.03 ? 45 ARG L CB 1 ATOM 2363 C CG . ARG B 2 45 ? -60.035 3.251 55.725 1.00 78.08 ? 45 ARG L CG 1 ATOM 2364 C CD . ARG B 2 45 ? -60.434 4.062 54.505 1.00 78.39 ? 45 ARG L CD 1 ATOM 2365 N NE . ARG B 2 45 ? -59.303 4.702 53.847 1.00 78.61 ? 45 ARG L NE 1 ATOM 2366 C CZ . ARG B 2 45 ? -59.410 5.522 52.802 1.00 79.26 ? 45 ARG L CZ 1 ATOM 2367 N NH1 . ARG B 2 45 ? -60.602 5.809 52.289 1.00 79.41 ? 45 ARG L NH1 1 ATOM 2368 N NH2 . ARG B 2 45 ? -58.320 6.060 52.266 1.00 79.37 ? 45 ARG L NH2 1 ATOM 2369 N N . LEU B 2 46 ? -59.336 2.870 59.353 1.00 76.02 ? 46 LEU L N 1 ATOM 2370 C CA . LEU B 2 46 ? -58.651 3.765 60.286 1.00 75.88 ? 46 LEU L CA 1 ATOM 2371 C C . LEU B 2 46 ? -58.141 5.014 59.566 1.00 75.57 ? 46 LEU L C 1 ATOM 2372 O O . LEU B 2 46 ? -57.376 4.917 58.606 1.00 75.53 ? 46 LEU L O 1 ATOM 2373 C CB . LEU B 2 46 ? -57.488 3.028 60.960 1.00 75.84 ? 46 LEU L CB 1 ATOM 2374 C CG . LEU B 2 46 ? -56.684 3.762 62.038 1.00 75.69 ? 46 LEU L CG 1 ATOM 2375 C CD1 . LEU B 2 46 ? -57.540 4.063 63.259 1.00 75.10 ? 46 LEU L CD1 1 ATOM 2376 C CD2 . LEU B 2 46 ? -55.465 2.935 62.430 1.00 75.38 ? 46 LEU L CD2 1 ATOM 2377 N N . LEU B 2 47 ? -58.583 6.180 60.034 1.00 76.23 ? 47 LEU L N 1 ATOM 2378 C CA . LEU B 2 47 ? -58.231 7.464 59.426 1.00 76.36 ? 47 LEU L CA 1 ATOM 2379 C C . LEU B 2 47 ? -57.165 8.181 60.243 1.00 76.15 ? 47 LEU L C 1 ATOM 2380 O O . LEU B 2 47 ? -56.114 8.554 59.722 1.00 75.85 ? 47 LEU L O 1 ATOM 2381 C CB . LEU B 2 47 ? -59.464 8.365 59.343 1.00 76.46 ? 47 LEU L CB 1 ATOM 2382 C CG . LEU B 2 47 ? -60.645 7.898 58.501 1.00 76.81 ? 47 LEU L CG 1 ATOM 2383 C CD1 . LEU B 2 47 ? -61.801 8.874 58.679 1.00 77.58 ? 47 LEU L CD1 1 ATOM 2384 C CD2 . LEU B 2 47 ? -60.255 7.778 57.037 1.00 76.40 ? 47 LEU L CD2 1 ATOM 2385 N N . ILE B 2 48 ? -57.463 8.383 61.524 1.00 76.63 ? 48 ILE L N 1 ATOM 2386 C CA . ILE B 2 48 ? -56.590 9.119 62.432 1.00 76.84 ? 48 ILE L CA 1 ATOM 2387 C C . ILE B 2 48 ? -56.297 8.265 63.663 1.00 77.44 ? 48 ILE L C 1 ATOM 2388 O O . ILE B 2 48 ? -57.156 7.529 64.146 1.00 78.39 ? 48 ILE L O 1 ATOM 2389 C CB . ILE B 2 48 ? -57.223 10.466 62.857 1.00 76.37 ? 48 ILE L CB 1 ATOM 2390 C CG1 . ILE B 2 48 ? -57.487 11.350 61.631 1.00 75.84 ? 48 ILE L CG1 1 ATOM 2391 C CG2 . ILE B 2 48 ? -56.326 11.202 63.838 1.00 76.31 ? 48 ILE L CG2 1 ATOM 2392 C CD1 . ILE B 2 48 ? -56.240 11.734 60.858 1.00 75.14 ? 48 ILE L CD1 1 ATOM 2393 N N . GLU B 2 49 ? -55.072 8.387 64.158 1.00 77.96 ? 49 GLU L N 1 ATOM 2394 C CA . GLU B 2 49 ? -54.527 7.515 65.186 1.00 77.48 ? 49 GLU L CA 1 ATOM 2395 C C . GLU B 2 49 ? -54.070 8.385 66.357 1.00 77.35 ? 49 GLU L C 1 ATOM 2396 O O . GLU B 2 49 ? -53.384 9.389 66.156 1.00 77.22 ? 49 GLU L O 1 ATOM 2397 C CB . GLU B 2 49 ? -53.331 6.767 64.596 1.00 78.50 ? 49 GLU L CB 1 ATOM 2398 C CG . GLU B 2 49 ? -53.014 5.425 65.222 1.00 78.33 ? 49 GLU L CG 1 ATOM 2399 C CD . GLU B 2 49 ? -51.715 4.843 64.686 0.50 77.49 ? 49 GLU L CD 1 ATOM 2400 O OE1 . GLU B 2 49 ? -50.706 5.576 64.649 0.50 76.95 ? 49 GLU L OE1 1 ATOM 2401 O OE2 . GLU B 2 49 ? -51.702 3.659 64.297 0.50 77.46 ? 49 GLU L OE2 1 ATOM 2402 N N . TYR B 2 50 ? -54.457 8.004 67.571 1.00 77.02 ? 50 TYR L N 1 ATOM 2403 C CA . TYR B 2 50 ? -54.055 8.719 68.783 1.00 77.28 ? 50 TYR L CA 1 ATOM 2404 C C . TYR B 2 50 ? -54.301 10.220 68.668 1.00 77.76 ? 50 TYR L C 1 ATOM 2405 O O . TYR B 2 50 ? -53.360 11.017 68.679 1.00 78.27 ? 50 TYR L O 1 ATOM 2406 C CB . TYR B 2 50 ? -52.582 8.446 69.113 1.00 76.51 ? 50 TYR L CB 1 ATOM 2407 C CG . TYR B 2 50 ? -52.310 7.011 69.482 1.00 76.42 ? 50 TYR L CG 1 ATOM 2408 C CD1 . TYR B 2 50 ? -52.688 6.512 70.722 1.00 76.64 ? 50 TYR L CD1 1 ATOM 2409 C CD2 . TYR B 2 50 ? -51.683 6.150 68.592 1.00 76.53 ? 50 TYR L CD2 1 ATOM 2410 C CE1 . TYR B 2 50 ? -52.448 5.192 71.066 1.00 76.60 ? 50 TYR L CE1 1 ATOM 2411 C CE2 . TYR B 2 50 ? -51.438 4.829 68.926 1.00 76.46 ? 50 TYR L CE2 1 ATOM 2412 C CZ . TYR B 2 50 ? -51.825 4.356 70.165 1.00 76.39 ? 50 TYR L CZ 1 ATOM 2413 O OH . TYR B 2 50 ? -51.589 3.049 70.510 1.00 76.47 ? 50 TYR L OH 1 ATOM 2414 N N . ALA B 2 51 ? -55.571 10.593 68.539 1.00 77.83 ? 51 ALA L N 1 ATOM 2415 C CA . ALA B 2 51 ? -55.981 11.998 68.502 1.00 78.10 ? 51 ALA L CA 1 ATOM 2416 C C . ALA B 2 51 ? -55.656 12.690 67.177 1.00 78.81 ? 51 ALA L C 1 ATOM 2417 O O . ALA B 2 51 ? -56.566 13.133 66.476 1.00 79.48 ? 51 ALA L O 1 ATOM 2418 C CB . ALA B 2 51 ? -55.365 12.767 69.666 1.00 78.27 ? 51 ALA L CB 1 ATOM 2419 N N . SER B 2 52 ? -54.370 12.787 66.839 1.00 78.53 ? 52 SER L N 1 ATOM 2420 C CA . SER B 2 52 ? -53.935 13.601 65.699 1.00 78.43 ? 52 SER L CA 1 ATOM 2421 C C . SER B 2 52 ? -52.875 12.977 64.771 1.00 78.15 ? 52 SER L C 1 ATOM 2422 O O . SER B 2 52 ? -52.566 13.556 63.728 1.00 78.31 ? 52 SER L O 1 ATOM 2423 C CB . SER B 2 52 ? -53.427 14.952 66.215 1.00 79.42 ? 52 SER L CB 1 ATOM 2424 O OG . SER B 2 52 ? -52.494 14.776 67.268 1.00 79.97 ? 52 SER L OG 1 ATOM 2425 N N . GLU B 2 53 ? -52.323 11.817 65.126 1.00 78.05 ? 53 GLU L N 1 ATOM 2426 C CA . GLU B 2 53 ? -51.277 11.192 64.301 1.00 78.22 ? 53 GLU L CA 1 ATOM 2427 C C . GLU B 2 53 ? -51.882 10.563 63.045 1.00 77.58 ? 53 GLU L C 1 ATOM 2428 O O . GLU B 2 53 ? -52.825 9.771 63.128 1.00 76.42 ? 53 GLU L O 1 ATOM 2429 C CB . GLU B 2 53 ? -50.492 10.145 65.100 1.00 78.79 ? 53 GLU L CB 1 ATOM 2430 C CG . GLU B 2 53 ? -49.661 10.729 66.243 1.00 79.08 ? 53 GLU L CG 1 ATOM 2431 C CD . GLU B 2 53 ? -49.305 9.701 67.306 0.50 78.84 ? 53 GLU L CD 1 ATOM 2432 O OE1 . GLU B 2 53 ? -49.219 8.497 66.977 0.50 79.04 ? 53 GLU L OE1 1 ATOM 2433 O OE2 . GLU B 2 53 ? -49.110 10.101 68.474 0.50 78.68 ? 53 GLU L OE2 1 ATOM 2434 N N . SER B 2 54 ? -51.327 10.919 61.886 1.00 77.45 ? 54 SER L N 1 ATOM 2435 C CA . SER B 2 54 ? -51.897 10.531 60.594 1.00 77.49 ? 54 SER L CA 1 ATOM 2436 C C . SER B 2 54 ? -51.460 9.134 60.160 1.00 76.89 ? 54 SER L C 1 ATOM 2437 O O . SER B 2 54 ? -50.350 8.697 60.462 1.00 76.04 ? 54 SER L O 1 ATOM 2438 C CB . SER B 2 54 ? -51.509 11.550 59.520 1.00 77.33 ? 54 SER L CB 1 ATOM 2439 O OG . SER B 2 54 ? -50.102 11.672 59.416 1.00 77.37 ? 54 SER L OG 1 ATOM 2440 N N . ILE B 2 55 ? -52.349 8.445 59.445 1.00 77.48 ? 55 ILE L N 1 ATOM 2441 C CA . ILE B 2 55 ? -52.075 7.112 58.910 1.00 77.78 ? 55 ILE L CA 1 ATOM 2442 C C . ILE B 2 55 ? -51.630 7.226 57.455 1.00 77.92 ? 55 ILE L C 1 ATOM 2443 O O . ILE B 2 55 ? -52.138 8.063 56.708 1.00 77.88 ? 55 ILE L O 1 ATOM 2444 C CB . ILE B 2 55 ? -53.330 6.210 58.977 1.00 77.58 ? 55 ILE L CB 1 ATOM 2445 C CG1 . ILE B 2 55 ? -53.780 6.013 60.427 1.00 77.89 ? 55 ILE L CG1 1 ATOM 2446 C CG2 . ILE B 2 55 ? -53.060 4.857 58.328 1.00 77.38 ? 55 ILE L CG2 1 ATOM 2447 C CD1 . ILE B 2 55 ? -52.846 5.149 61.249 1.00 78.45 ? 55 ILE L CD1 1 ATOM 2448 N N . SER B 2 56 ? -50.684 6.377 57.059 1.00 78.20 ? 56 SER L N 1 ATOM 2449 C CA . SER B 2 56 ? -50.177 6.363 55.688 1.00 78.43 ? 56 SER L CA 1 ATOM 2450 C C . SER B 2 56 ? -51.248 5.866 54.720 1.00 78.32 ? 56 SER L C 1 ATOM 2451 O O . SER B 2 56 ? -51.933 4.878 54.997 1.00 78.56 ? 56 SER L O 1 ATOM 2452 C CB . SER B 2 56 ? -48.934 5.474 55.592 1.00 79.83 ? 56 SER L CB 1 ATOM 2453 O OG . SER B 2 56 ? -48.429 5.429 54.268 1.00 80.66 ? 56 SER L OG 1 ATOM 2454 N N . GLY B 2 57 ? -51.390 6.563 53.593 1.00 78.08 ? 57 GLY L N 1 ATOM 2455 C CA . GLY B 2 57 ? -52.386 6.217 52.577 1.00 78.24 ? 57 GLY L CA 1 ATOM 2456 C C . GLY B 2 57 ? -53.749 6.868 52.772 1.00 78.78 ? 57 GLY L C 1 ATOM 2457 O O . GLY B 2 57 ? -54.689 6.570 52.033 1.00 79.46 ? 57 GLY L O 1 ATOM 2458 N N . ILE B 2 58 ? -53.862 7.752 53.765 1.00 78.30 ? 58 ILE L N 1 ATOM 2459 C CA . ILE B 2 58 ? -55.096 8.500 54.011 1.00 77.64 ? 58 ILE L CA 1 ATOM 2460 C C . ILE B 2 58 ? -54.949 9.924 53.466 1.00 77.34 ? 58 ILE L C 1 ATOM 2461 O O . ILE B 2 58 ? -53.908 10.552 53.665 1.00 77.48 ? 58 ILE L O 1 ATOM 2462 C CB . ILE B 2 58 ? -55.422 8.563 55.521 1.00 77.79 ? 58 ILE L CB 1 ATOM 2463 C CG1 . ILE B 2 58 ? -55.589 7.153 56.100 1.00 78.16 ? 58 ILE L CG1 1 ATOM 2464 C CG2 . ILE B 2 58 ? -56.686 9.375 55.770 1.00 78.07 ? 58 ILE L CG2 1 ATOM 2465 C CD1 . ILE B 2 58 ? -56.690 6.330 55.444 1.00 77.78 ? 58 ILE L CD1 1 ATOM 2466 N N . PRO B 2 59 ? -55.985 10.439 52.768 1.00 76.91 ? 59 PRO L N 1 ATOM 2467 C CA . PRO B 2 59 ? -55.941 11.809 52.245 1.00 76.92 ? 59 PRO L CA 1 ATOM 2468 C C . PRO B 2 59 ? -55.589 12.860 53.300 1.00 76.56 ? 59 PRO L C 1 ATOM 2469 O O . PRO B 2 59 ? -55.888 12.678 54.482 1.00 75.97 ? 59 PRO L O 1 ATOM 2470 C CB . PRO B 2 59 ? -57.365 12.035 51.728 1.00 76.37 ? 59 PRO L CB 1 ATOM 2471 C CG . PRO B 2 59 ? -57.870 10.692 51.413 1.00 76.08 ? 59 PRO L CG 1 ATOM 2472 C CD . PRO B 2 59 ? -57.243 9.760 52.403 1.00 76.40 ? 59 PRO L CD 1 ATOM 2473 N N . SER B 2 60 ? -54.968 13.951 52.857 1.00 76.88 ? 60 SER L N 1 ATOM 2474 C CA . SER B 2 60 ? -54.484 14.998 53.760 1.00 77.22 ? 60 SER L CA 1 ATOM 2475 C C . SER B 2 60 ? -55.614 15.805 54.406 1.00 77.88 ? 60 SER L C 1 ATOM 2476 O O . SER B 2 60 ? -55.427 16.379 55.481 1.00 78.55 ? 60 SER L O 1 ATOM 2477 C CB . SER B 2 60 ? -53.545 15.947 53.014 1.00 77.41 ? 60 SER L CB 1 ATOM 2478 O OG . SER B 2 60 ? -54.238 16.654 52.001 1.00 77.78 ? 60 SER L OG 1 ATOM 2479 N N . ARG B 2 61 ? -56.774 15.853 53.750 1.00 77.47 ? 61 ARG L N 1 ATOM 2480 C CA . ARG B 2 61 ? -57.935 16.590 54.272 1.00 77.36 ? 61 ARG L CA 1 ATOM 2481 C C . ARG B 2 61 ? -58.417 16.077 55.636 1.00 76.80 ? 61 ARG L C 1 ATOM 2482 O O . ARG B 2 61 ? -58.994 16.835 56.417 1.00 75.97 ? 61 ARG L O 1 ATOM 2483 C CB . ARG B 2 61 ? -59.094 16.575 53.264 1.00 77.49 ? 61 ARG L CB 1 ATOM 2484 C CG . ARG B 2 61 ? -59.640 15.191 52.921 1.00 77.49 ? 61 ARG L CG 1 ATOM 2485 C CD . ARG B 2 61 ? -60.800 15.284 51.937 1.00 77.69 ? 61 ARG L CD 1 ATOM 2486 N NE . ARG B 2 61 ? -61.177 13.974 51.403 1.00 77.71 ? 61 ARG L NE 1 ATOM 2487 C CZ . ARG B 2 61 ? -60.562 13.353 50.396 1.00 77.98 ? 61 ARG L CZ 1 ATOM 2488 N NH1 . ARG B 2 61 ? -59.517 13.907 49.785 1.00 78.24 ? 61 ARG L NH1 1 ATOM 2489 N NH2 . ARG B 2 61 ? -60.992 12.162 49.997 1.00 78.03 ? 61 ARG L NH2 1 ATOM 2490 N N . PHE B 2 62 ? -58.180 14.796 55.913 1.00 77.14 ? 62 PHE L N 1 ATOM 2491 C CA . PHE B 2 62 ? -58.508 14.214 57.215 1.00 77.62 ? 62 PHE L CA 1 ATOM 2492 C C . PHE B 2 62 ? -57.441 14.572 58.252 1.00 78.01 ? 62 PHE L C 1 ATOM 2493 O O . PHE B 2 62 ? -56.271 14.199 58.109 1.00 77.94 ? 62 PHE L O 1 ATOM 2494 C CB . PHE B 2 62 ? -58.643 12.694 57.108 1.00 78.31 ? 62 PHE L CB 1 ATOM 2495 C CG . PHE B 2 62 ? -59.769 12.250 56.224 1.00 78.51 ? 62 PHE L CG 1 ATOM 2496 C CD1 . PHE B 2 62 ? -61.036 12.033 56.746 1.00 78.65 ? 62 PHE L CD1 1 ATOM 2497 C CD2 . PHE B 2 62 ? -59.565 12.056 54.866 1.00 78.54 ? 62 PHE L CD2 1 ATOM 2498 C CE1 . PHE B 2 62 ? -62.081 11.627 55.929 1.00 78.65 ? 62 PHE L CE1 1 ATOM 2499 C CE2 . PHE B 2 62 ? -60.604 11.652 54.040 1.00 78.43 ? 62 PHE L CE2 1 ATOM 2500 C CZ . PHE B 2 62 ? -61.864 11.436 54.572 1.00 78.63 ? 62 PHE L CZ 1 ATOM 2501 N N . SER B 2 63 ? -57.853 15.307 59.283 1.00 77.88 ? 63 SER L N 1 ATOM 2502 C CA . SER B 2 63 ? -56.986 15.644 60.410 1.00 77.47 ? 63 SER L CA 1 ATOM 2503 C C . SER B 2 63 ? -57.750 15.476 61.720 1.00 77.31 ? 63 SER L C 1 ATOM 2504 O O . SER B 2 63 ? -58.982 15.462 61.732 1.00 77.08 ? 63 SER L O 1 ATOM 2505 C CB . SER B 2 63 ? -56.468 17.080 60.281 1.00 77.22 ? 63 SER L CB 1 ATOM 2506 O OG . SER B 2 63 ? -57.531 18.019 60.295 1.00 77.05 ? 63 SER L OG 1 ATOM 2507 N N . GLY B 2 64 ? -57.012 15.348 62.818 1.00 77.55 ? 64 GLY L N 1 ATOM 2508 C CA . GLY B 2 64 ? -57.612 15.178 64.138 1.00 77.59 ? 64 GLY L CA 1 ATOM 2509 C C . GLY B 2 64 ? -56.988 16.094 65.172 1.00 77.52 ? 64 GLY L C 1 ATOM 2510 O O . GLY B 2 64 ? -55.933 16.680 64.936 1.00 77.77 ? 64 GLY L O 1 ATOM 2511 N N . SER B 2 65 ? -57.653 16.218 66.318 1.00 77.78 ? 65 SER L N 1 ATOM 2512 C CA . SER B 2 65 ? -57.169 17.053 67.417 1.00 78.05 ? 65 SER L CA 1 ATOM 2513 C C . SER B 2 65 ? -57.857 16.686 68.732 1.00 78.72 ? 65 SER L C 1 ATOM 2514 O O . SER B 2 65 ? -58.784 15.871 68.754 1.00 79.59 ? 65 SER L O 1 ATOM 2515 C CB . SER B 2 65 ? -57.413 18.531 67.109 1.00 77.99 ? 65 SER L CB 1 ATOM 2516 O OG . SER B 2 65 ? -58.801 18.811 67.042 1.00 77.97 ? 65 SER L OG 1 ATOM 2517 N N . GLY B 2 66 ? -57.394 17.294 69.821 1.00 78.24 ? 66 GLY L N 1 ATOM 2518 C CA . GLY B 2 66 ? -58.020 17.131 71.130 1.00 78.15 ? 66 GLY L CA 1 ATOM 2519 C C . GLY B 2 66 ? -57.190 16.322 72.109 1.00 78.08 ? 66 GLY L C 1 ATOM 2520 O O . GLY B 2 66 ? -56.238 15.637 71.724 1.00 77.59 ? 66 GLY L O 1 ATOM 2521 N N . SER B 2 67 ? -57.561 16.414 73.384 1.00 78.26 ? 67 SER L N 1 ATOM 2522 C CA . SER B 2 67 ? -56.908 15.661 74.451 1.00 78.22 ? 67 SER L CA 1 ATOM 2523 C C . SER B 2 67 ? -57.776 15.664 75.708 1.00 78.21 ? 67 SER L C 1 ATOM 2524 O O . SER B 2 67 ? -58.406 16.672 76.032 1.00 78.53 ? 67 SER L O 1 ATOM 2525 C CB . SER B 2 67 ? -55.533 16.256 74.768 1.00 78.51 ? 67 SER L CB 1 ATOM 2526 O OG . SER B 2 67 ? -55.635 17.626 75.119 1.00 78.66 ? 67 SER L OG 1 ATOM 2527 N N . GLY B 2 68 ? -57.807 14.533 76.407 1.00 77.88 ? 68 GLY L N 1 ATOM 2528 C CA . GLY B 2 68 ? -58.573 14.401 77.643 1.00 77.77 ? 68 GLY L CA 1 ATOM 2529 C C . GLY B 2 68 ? -59.948 13.804 77.411 1.00 77.50 ? 68 GLY L C 1 ATOM 2530 O O . GLY B 2 68 ? -60.089 12.585 77.297 1.00 77.54 ? 68 GLY L O 1 ATOM 2531 N N . THR B 2 69 ? -60.961 14.665 77.344 1.00 77.37 ? 69 THR L N 1 ATOM 2532 C CA . THR B 2 69 ? -62.350 14.223 77.199 1.00 77.54 ? 69 THR L CA 1 ATOM 2533 C C . THR B 2 69 ? -62.934 14.551 75.823 1.00 77.19 ? 69 THR L C 1 ATOM 2534 O O . THR B 2 69 ? -63.628 13.725 75.239 1.00 77.57 ? 69 THR L O 1 ATOM 2535 C CB . THR B 2 69 ? -63.252 14.840 78.289 1.00 78.30 ? 69 THR L CB 1 ATOM 2536 O OG1 . THR B 2 69 ? -63.224 16.269 78.191 1.00 79.04 ? 69 THR L OG1 1 ATOM 2537 C CG2 . THR B 2 69 ? -62.783 14.414 79.678 1.00 77.81 ? 69 THR L CG2 1 ATOM 2538 N N . ASP B 2 70 ? -62.657 15.753 75.317 1.00 77.07 ? 70 ASP L N 1 ATOM 2539 C CA . ASP B 2 70 ? -63.175 16.194 74.016 1.00 76.89 ? 70 ASP L CA 1 ATOM 2540 C C . ASP B 2 70 ? -62.182 15.907 72.894 1.00 76.59 ? 70 ASP L C 1 ATOM 2541 O O . ASP B 2 70 ? -60.979 16.117 73.054 1.00 76.85 ? 70 ASP L O 1 ATOM 2542 C CB . ASP B 2 70 ? -63.486 17.692 74.042 1.00 77.90 ? 70 ASP L CB 1 ATOM 2543 C CG . ASP B 2 70 ? -64.512 18.062 75.101 1.00 79.29 ? 70 ASP L CG 1 ATOM 2544 O OD1 . ASP B 2 70 ? -64.564 19.252 75.487 1.00 79.72 ? 70 ASP L OD1 1 ATOM 2545 O OD2 . ASP B 2 70 ? -65.264 17.169 75.550 1.00 79.66 ? 70 ASP L OD2 1 ATOM 2546 N N . PHE B 2 71 ? -62.697 15.428 71.762 1.00 76.15 ? 71 PHE L N 1 ATOM 2547 C CA . PHE B 2 71 ? -61.880 15.130 70.582 1.00 75.63 ? 71 PHE L CA 1 ATOM 2548 C C . PHE B 2 71 ? -62.621 15.529 69.309 1.00 75.40 ? 71 PHE L C 1 ATOM 2549 O O . PHE B 2 71 ? -63.852 15.570 69.289 1.00 75.46 ? 71 PHE L O 1 ATOM 2550 C CB . PHE B 2 71 ? -61.533 13.640 70.533 1.00 75.21 ? 71 PHE L CB 1 ATOM 2551 C CG . PHE B 2 71 ? -60.747 13.164 71.717 1.00 74.91 ? 71 PHE L CG 1 ATOM 2552 C CD1 . PHE B 2 71 ? -61.389 12.597 72.810 1.00 75.08 ? 71 PHE L CD1 1 ATOM 2553 C CD2 . PHE B 2 71 ? -59.364 13.299 71.748 1.00 74.94 ? 71 PHE L CD2 1 ATOM 2554 C CE1 . PHE B 2 71 ? -60.664 12.162 73.915 1.00 75.37 ? 71 PHE L CE1 1 ATOM 2555 C CE2 . PHE B 2 71 ? -58.630 12.869 72.849 1.00 75.18 ? 71 PHE L CE2 1 ATOM 2556 C CZ . PHE B 2 71 ? -59.282 12.298 73.934 1.00 75.28 ? 71 PHE L CZ 1 ATOM 2557 N N . THR B 2 72 ? -61.865 15.821 68.251 1.00 74.92 ? 72 THR L N 1 ATOM 2558 C CA . THR B 2 72 ? -62.440 16.326 67.003 1.00 74.63 ? 72 THR L CA 1 ATOM 2559 C C . THR B 2 72 ? -61.746 15.751 65.772 1.00 74.16 ? 72 THR L C 1 ATOM 2560 O O . THR B 2 72 ? -60.520 15.746 65.688 1.00 73.84 ? 72 THR L O 1 ATOM 2561 C CB . THR B 2 72 ? -62.347 17.868 66.924 1.00 74.52 ? 72 THR L CB 1 ATOM 2562 O OG1 . THR B 2 72 ? -62.891 18.452 68.114 1.00 74.56 ? 72 THR L OG1 1 ATOM 2563 C CG2 . THR B 2 72 ? -63.104 18.396 65.709 1.00 74.36 ? 72 THR L CG2 1 ATOM 2564 N N . LEU B 2 73 ? -62.549 15.266 64.827 1.00 74.14 ? 73 LEU L N 1 ATOM 2565 C CA . LEU B 2 73 ? -62.076 14.915 63.491 1.00 74.43 ? 73 LEU L CA 1 ATOM 2566 C C . LEU B 2 73 ? -62.564 15.986 62.531 1.00 74.83 ? 73 LEU L C 1 ATOM 2567 O O . LEU B 2 73 ? -63.712 16.415 62.619 1.00 75.28 ? 73 LEU L O 1 ATOM 2568 C CB . LEU B 2 73 ? -62.624 13.552 63.070 1.00 73.63 ? 73 LEU L CB 1 ATOM 2569 C CG . LEU B 2 73 ? -62.286 13.060 61.661 1.00 73.34 ? 73 LEU L CG 1 ATOM 2570 C CD1 . LEU B 2 73 ? -60.788 12.809 61.514 1.00 71.93 ? 73 LEU L CD1 1 ATOM 2571 C CD2 . LEU B 2 73 ? -63.080 11.803 61.342 1.00 73.72 ? 73 LEU L CD2 1 ATOM 2572 N N . THR B 2 74 ? -61.697 16.412 61.616 1.00 75.33 ? 74 THR L N 1 ATOM 2573 C CA . THR B 2 74 ? -62.018 17.507 60.703 1.00 76.06 ? 74 THR L CA 1 ATOM 2574 C C . THR B 2 74 ? -61.634 17.180 59.262 1.00 76.87 ? 74 THR L C 1 ATOM 2575 O O . THR B 2 74 ? -60.552 16.653 59.002 1.00 77.43 ? 74 THR L O 1 ATOM 2576 C CB . THR B 2 74 ? -61.307 18.806 61.132 1.00 75.92 ? 74 THR L CB 1 ATOM 2577 O OG1 . THR B 2 74 ? -61.690 19.138 62.473 1.00 76.30 ? 74 THR L OG1 1 ATOM 2578 C CG2 . THR B 2 74 ? -61.670 19.962 60.202 1.00 75.63 ? 74 THR L CG2 1 ATOM 2579 N N . ILE B 2 75 ? -62.538 17.493 58.334 1.00 77.14 ? 75 ILE L N 1 ATOM 2580 C CA . ILE B 2 75 ? -62.267 17.377 56.906 1.00 77.75 ? 75 ILE L CA 1 ATOM 2581 C C . ILE B 2 75 ? -62.081 18.780 56.336 1.00 78.38 ? 75 ILE L C 1 ATOM 2582 O O . ILE B 2 75 ? -63.002 19.595 56.384 1.00 78.45 ? 75 ILE L O 1 ATOM 2583 C CB . ILE B 2 75 ? -63.419 16.667 56.167 1.00 77.34 ? 75 ILE L CB 1 ATOM 2584 C CG1 . ILE B 2 75 ? -63.736 15.325 56.831 1.00 77.45 ? 75 ILE L CG1 1 ATOM 2585 C CG2 . ILE B 2 75 ? -63.060 16.453 54.708 1.00 77.34 ? 75 ILE L CG2 1 ATOM 2586 C CD1 . ILE B 2 75 ? -64.760 14.500 56.083 1.00 77.80 ? 75 ILE L CD1 1 ATOM 2587 N N . ASN B 2 76 ? -60.888 19.060 55.811 1.00 79.06 ? 76 ASN L N 1 ATOM 2588 C CA . ASN B 2 76 ? -60.558 20.391 55.285 1.00 79.99 ? 76 ASN L CA 1 ATOM 2589 C C . ASN B 2 76 ? -61.493 20.804 54.157 1.00 80.84 ? 76 ASN L C 1 ATOM 2590 O O . ASN B 2 76 ? -62.127 21.860 54.216 1.00 81.09 ? 76 ASN L O 1 ATOM 2591 C CB . ASN B 2 76 ? -59.112 20.433 54.775 1.00 81.29 ? 76 ASN L CB 1 ATOM 2592 C CG . ASN B 2 76 ? -58.093 20.277 55.886 1.00 83.10 ? 76 ASN L CG 1 ATOM 2593 O OD1 . ASN B 2 76 ? -58.390 19.727 56.948 1.00 84.32 ? 76 ASN L OD1 1 ATOM 2594 N ND2 . ASN B 2 76 ? -56.877 20.757 55.643 1.00 83.30 ? 76 ASN L ND2 1 ATOM 2595 N N . SER B 2 77 ? -61.560 19.961 53.131 1.00 81.10 ? 77 SER L N 1 ATOM 2596 C CA . SER B 2 77 ? -62.423 20.190 51.978 1.00 81.09 ? 77 SER L CA 1 ATOM 2597 C C . SER B 2 77 ? -63.158 18.895 51.652 1.00 81.15 ? 77 SER L C 1 ATOM 2598 O O . SER B 2 77 ? -62.569 17.962 51.106 1.00 81.10 ? 77 SER L O 1 ATOM 2599 C CB . SER B 2 77 ? -61.593 20.651 50.778 1.00 81.67 ? 77 SER L CB 1 ATOM 2600 O OG . SER B 2 77 ? -62.413 20.903 49.651 1.00 82.28 ? 77 SER L OG 1 ATOM 2601 N N . VAL B 2 78 ? -64.441 18.844 51.999 1.00 81.27 ? 78 VAL L N 1 ATOM 2602 C CA . VAL B 2 78 ? -65.231 17.622 51.860 1.00 81.36 ? 78 VAL L CA 1 ATOM 2603 C C . VAL B 2 78 ? -65.498 17.307 50.390 1.00 81.44 ? 78 VAL L C 1 ATOM 2604 O O . VAL B 2 78 ? -65.829 18.198 49.607 1.00 81.70 ? 78 VAL L O 1 ATOM 2605 C CB . VAL B 2 78 ? -66.577 17.730 52.608 1.00 81.29 ? 78 VAL L CB 1 ATOM 2606 C CG1 . VAL B 2 78 ? -67.422 16.482 52.383 1.00 81.28 ? 78 VAL L CG1 1 ATOM 2607 C CG2 . VAL B 2 78 ? -66.341 17.951 54.092 1.00 81.63 ? 78 VAL L CG2 1 ATOM 2608 N N . GLU B 2 79 ? -65.339 16.036 50.028 1.00 81.21 ? 79 GLU L N 1 ATOM 2609 C CA . GLU B 2 79 ? -65.614 15.567 48.676 1.00 81.82 ? 79 GLU L CA 1 ATOM 2610 C C . GLU B 2 79 ? -66.766 14.568 48.678 1.00 81.90 ? 79 GLU L C 1 ATOM 2611 O O . GLU B 2 79 ? -67.133 14.031 49.723 1.00 82.05 ? 79 GLU L O 1 ATOM 2612 C CB . GLU B 2 79 ? -64.361 14.935 48.069 1.00 82.52 ? 79 GLU L CB 1 ATOM 2613 C CG . GLU B 2 79 ? -63.265 15.948 47.750 1.00 83.07 ? 79 GLU L CG 1 ATOM 2614 C CD . GLU B 2 79 ? -62.116 15.348 46.956 1.00 83.11 ? 79 GLU L CD 1 ATOM 2615 O OE1 . GLU B 2 79 ? -61.725 14.195 47.243 1.00 83.81 ? 79 GLU L OE1 1 ATOM 2616 O OE2 . GLU B 2 79 ? -61.600 16.036 46.049 1.00 83.11 ? 79 GLU L OE2 1 ATOM 2617 N N . SER B 2 80 ? -67.326 14.326 47.495 1.00 82.00 ? 80 SER L N 1 ATOM 2618 C CA . SER B 2 80 ? -68.517 13.484 47.339 1.00 81.44 ? 80 SER L CA 1 ATOM 2619 C C . SER B 2 80 ? -68.321 12.052 47.844 1.00 81.19 ? 80 SER L C 1 ATOM 2620 O O . SER B 2 80 ? -69.261 11.440 48.353 1.00 80.96 ? 80 SER L O 1 ATOM 2621 C CB . SER B 2 80 ? -68.946 13.451 45.872 1.00 80.74 ? 80 SER L CB 1 ATOM 2622 O OG . SER B 2 80 ? -67.909 12.944 45.052 1.00 80.65 ? 80 SER L OG 1 ATOM 2623 N N . GLU B 2 81 ? -67.102 11.531 47.709 1.00 81.31 ? 81 GLU L N 1 ATOM 2624 C CA . GLU B 2 81 ? -66.794 10.153 48.118 1.00 81.69 ? 81 GLU L CA 1 ATOM 2625 C C . GLU B 2 81 ? -66.527 10.011 49.624 1.00 81.95 ? 81 GLU L C 1 ATOM 2626 O O . GLU B 2 81 ? -66.226 8.915 50.100 1.00 82.19 ? 81 GLU L O 1 ATOM 2627 C CB . GLU B 2 81 ? -65.612 9.584 47.310 1.00 82.70 ? 81 GLU L CB 1 ATOM 2628 C CG . GLU B 2 81 ? -64.354 10.464 47.271 1.00 84.16 ? 81 GLU L CG 1 ATOM 2629 C CD . GLU B 2 81 ? -64.214 11.272 45.976 1.00 85.09 ? 81 GLU L CD 1 ATOM 2630 O OE1 . GLU B 2 81 ? -65.246 11.657 45.380 1.00 84.77 ? 81 GLU L OE1 1 ATOM 2631 O OE2 . GLU B 2 81 ? -63.061 11.524 45.559 1.00 85.60 ? 81 GLU L OE2 1 ATOM 2632 N N . ASP B 2 82 ? -66.655 11.108 50.369 1.00 81.79 ? 82 ASP L N 1 ATOM 2633 C CA . ASP B 2 82 ? -66.509 11.074 51.827 1.00 81.45 ? 82 ASP L CA 1 ATOM 2634 C C . ASP B 2 82 ? -67.800 10.655 52.534 1.00 80.81 ? 82 ASP L C 1 ATOM 2635 O O . ASP B 2 82 ? -67.826 10.555 53.762 1.00 80.74 ? 82 ASP L O 1 ATOM 2636 C CB . ASP B 2 82 ? -66.056 12.441 52.353 1.00 83.39 ? 82 ASP L CB 1 ATOM 2637 C CG . ASP B 2 82 ? -64.753 12.910 51.727 1.00 85.51 ? 82 ASP L CG 1 ATOM 2638 O OD1 . ASP B 2 82 ? -64.484 14.132 51.755 1.00 86.10 ? 82 ASP L OD1 1 ATOM 2639 O OD2 . ASP B 2 82 ? -64.002 12.062 51.201 1.00 86.42 ? 82 ASP L OD2 1 ATOM 2640 N N . ILE B 2 83 ? -68.871 10.429 51.773 1.00 80.53 ? 83 ILE L N 1 ATOM 2641 C CA . ILE B 2 83 ? -70.110 9.892 52.344 1.00 80.08 ? 83 ILE L CA 1 ATOM 2642 C C . ILE B 2 83 ? -69.835 8.557 53.034 1.00 80.20 ? 83 ILE L C 1 ATOM 2643 O O . ILE B 2 83 ? -69.394 7.593 52.404 1.00 80.83 ? 83 ILE L O 1 ATOM 2644 C CB . ILE B 2 83 ? -71.248 9.725 51.289 1.00 79.66 ? 83 ILE L CB 1 ATOM 2645 C CG1 . ILE B 2 83 ? -70.815 8.829 50.119 1.00 79.88 ? 83 ILE L CG1 1 ATOM 2646 C CG2 . ILE B 2 83 ? -71.698 11.081 50.776 1.00 79.65 ? 83 ILE L CG2 1 ATOM 2647 C CD1 . ILE B 2 83 ? -71.854 8.716 49.032 1.00 80.13 ? 83 ILE L CD1 1 ATOM 2648 N N . ALA B 2 84 ? -70.070 8.523 54.341 1.00 79.38 ? 84 ALA L N 1 ATOM 2649 C CA . ALA B 2 84 ? -69.830 7.328 55.134 1.00 78.75 ? 84 ALA L CA 1 ATOM 2650 C C . ALA B 2 84 ? -70.262 7.556 56.573 1.00 78.46 ? 84 ALA L C 1 ATOM 2651 O O . ALA B 2 84 ? -70.686 8.654 56.942 1.00 78.34 ? 84 ALA L O 1 ATOM 2652 C CB . ALA B 2 84 ? -68.358 6.954 55.087 1.00 78.25 ? 84 ALA L CB 1 ATOM 2653 N N . ASP B 2 85 ? -70.164 6.503 57.376 1.00 78.59 ? 85 ASP L N 1 ATOM 2654 C CA . ASP B 2 85 ? -70.298 6.623 58.818 1.00 78.62 ? 85 ASP L CA 1 ATOM 2655 C C . ASP B 2 85 ? -68.916 6.819 59.407 1.00 78.85 ? 85 ASP L C 1 ATOM 2656 O O . ASP B 2 85 ? -67.945 6.222 58.938 1.00 79.70 ? 85 ASP L O 1 ATOM 2657 C CB . ASP B 2 85 ? -70.943 5.375 59.410 1.00 79.56 ? 85 ASP L CB 1 ATOM 2658 C CG . ASP B 2 85 ? -72.390 5.225 59.007 1.00 80.95 ? 85 ASP L CG 1 ATOM 2659 O OD1 . ASP B 2 85 ? -73.125 6.235 59.034 1.00 81.44 ? 85 ASP L OD1 1 ATOM 2660 O OD2 . ASP B 2 85 ? -72.794 4.094 58.668 1.00 81.89 ? 85 ASP L OD2 1 ATOM 2661 N N . TYR B 2 86 ? -68.830 7.664 60.428 1.00 78.29 ? 86 TYR L N 1 ATOM 2662 C CA . TYR B 2 86 ? -67.567 7.941 61.091 1.00 77.77 ? 86 TYR L CA 1 ATOM 2663 C C . TYR B 2 86 ? -67.683 7.643 62.579 1.00 77.95 ? 86 TYR L C 1 ATOM 2664 O O . TYR B 2 86 ? -68.616 8.097 63.244 1.00 77.42 ? 86 TYR L O 1 ATOM 2665 C CB . TYR B 2 86 ? -67.153 9.393 60.856 1.00 76.12 ? 86 TYR L CB 1 ATOM 2666 C CG . TYR B 2 86 ? -66.786 9.673 59.419 1.00 75.65 ? 86 TYR L CG 1 ATOM 2667 C CD1 . TYR B 2 86 ? -67.764 9.968 58.476 1.00 75.65 ? 86 TYR L CD1 1 ATOM 2668 C CD2 . TYR B 2 86 ? -65.461 9.625 58.997 1.00 75.71 ? 86 TYR L CD2 1 ATOM 2669 C CE1 . TYR B 2 86 ? -67.432 10.217 57.150 1.00 75.91 ? 86 TYR L CE1 1 ATOM 2670 C CE2 . TYR B 2 86 ? -65.117 9.875 57.675 1.00 75.81 ? 86 TYR L CE2 1 ATOM 2671 C CZ . TYR B 2 86 ? -66.107 10.169 56.757 1.00 75.81 ? 86 TYR L CZ 1 ATOM 2672 O OH . TYR B 2 86 ? -65.770 10.416 55.449 1.00 75.79 ? 86 TYR L OH 1 ATOM 2673 N N . TYR B 2 87 ? -66.730 6.865 63.087 1.00 78.73 ? 87 TYR L N 1 ATOM 2674 C CA . TYR B 2 87 ? -66.730 6.430 64.477 1.00 78.50 ? 87 TYR L CA 1 ATOM 2675 C C . TYR B 2 87 ? -65.437 6.846 65.160 1.00 78.27 ? 87 TYR L C 1 ATOM 2676 O O . TYR B 2 87 ? -64.365 6.766 64.563 1.00 78.12 ? 87 TYR L O 1 ATOM 2677 C CB . TYR B 2 87 ? -66.864 4.907 64.550 1.00 78.87 ? 87 TYR L CB 1 ATOM 2678 C CG . TYR B 2 87 ? -68.143 4.363 63.960 1.00 78.79 ? 87 TYR L CG 1 ATOM 2679 C CD1 . TYR B 2 87 ? -69.311 4.307 64.715 1.00 79.07 ? 87 TYR L CD1 1 ATOM 2680 C CD2 . TYR B 2 87 ? -68.184 3.891 62.652 1.00 78.76 ? 87 TYR L CD2 1 ATOM 2681 C CE1 . TYR B 2 87 ? -70.491 3.803 64.180 1.00 79.11 ? 87 TYR L CE1 1 ATOM 2682 C CE2 . TYR B 2 87 ? -69.358 3.385 62.107 1.00 79.06 ? 87 TYR L CE2 1 ATOM 2683 C CZ . TYR B 2 87 ? -70.508 3.342 62.876 1.00 79.10 ? 87 TYR L CZ 1 ATOM 2684 O OH . TYR B 2 87 ? -71.676 2.841 62.342 1.00 79.01 ? 87 TYR L OH 1 ATOM 2685 N N . CYS B 2 88 ? -65.540 7.292 66.410 1.00 78.48 ? 88 CYS L N 1 ATOM 2686 C CA . CYS B 2 88 ? -64.368 7.416 67.267 1.00 78.85 ? 88 CYS L CA 1 ATOM 2687 C C . CYS B 2 88 ? -64.238 6.130 68.082 1.00 78.44 ? 88 CYS L C 1 ATOM 2688 O O . CYS B 2 88 ? -65.223 5.416 68.290 1.00 77.55 ? 88 CYS L O 1 ATOM 2689 C CB . CYS B 2 88 ? -64.461 8.650 68.179 1.00 79.98 ? 88 CYS L CB 1 ATOM 2690 S SG . CYS B 2 88 ? -65.833 8.657 69.353 1.00 82.10 ? 88 CYS L SG 1 ATOM 2691 N N . GLN B 2 89 ? -63.016 5.830 68.511 1.00 78.48 ? 89 GLN L N 1 ATOM 2692 C CA . GLN B 2 89 ? -62.740 4.646 69.322 1.00 78.46 ? 89 GLN L CA 1 ATOM 2693 C C . GLN B 2 89 ? -61.630 4.954 70.313 1.00 78.56 ? 89 GLN L C 1 ATOM 2694 O O . GLN B 2 89 ? -60.575 5.450 69.921 1.00 79.25 ? 89 GLN L O 1 ATOM 2695 C CB . GLN B 2 89 ? -62.305 3.480 68.434 1.00 78.31 ? 89 GLN L CB 1 ATOM 2696 C CG . GLN B 2 89 ? -62.093 2.158 69.183 1.00 78.42 ? 89 GLN L CG 1 ATOM 2697 C CD . GLN B 2 89 ? -60.886 1.375 68.681 1.00 79.12 ? 89 GLN L CD 1 ATOM 2698 O OE1 . GLN B 2 89 ? -59.795 1.927 68.516 1.00 80.34 ? 89 GLN L OE1 1 ATOM 2699 N NE2 . GLN B 2 89 ? -61.074 0.080 68.455 1.00 78.87 ? 89 GLN L NE2 1 ATOM 2700 N N . GLN B 2 90 ? -61.865 4.644 71.587 1.00 78.09 ? 90 GLN L N 1 ATOM 2701 C CA . GLN B 2 90 ? -60.843 4.809 72.624 1.00 77.77 ? 90 GLN L CA 1 ATOM 2702 C C . GLN B 2 90 ? -60.071 3.511 72.845 1.00 77.18 ? 90 GLN L C 1 ATOM 2703 O O . GLN B 2 90 ? -60.616 2.414 72.688 1.00 75.86 ? 90 GLN L O 1 ATOM 2704 C CB . GLN B 2 90 ? -61.458 5.299 73.942 1.00 77.49 ? 90 GLN L CB 1 ATOM 2705 C CG . GLN B 2 90 ? -62.388 4.299 74.649 1.00 77.37 ? 90 GLN L CG 1 ATOM 2706 C CD . GLN B 2 90 ? -61.665 3.321 75.563 1.00 76.28 ? 90 GLN L CD 1 ATOM 2707 O OE1 . GLN B 2 90 ? -60.542 3.568 76.003 1.00 76.13 ? 90 GLN L OE1 1 ATOM 2708 N NE2 . GLN B 2 90 ? -62.317 2.202 75.856 1.00 75.64 ? 90 GLN L NE2 1 ATOM 2709 N N . SER B 2 91 ? -58.795 3.655 73.201 1.00 78.19 ? 91 SER L N 1 ATOM 2710 C CA . SER B 2 91 ? -57.916 2.523 73.482 1.00 78.70 ? 91 SER L CA 1 ATOM 2711 C C . SER B 2 91 ? -57.186 2.711 74.812 1.00 79.51 ? 91 SER L C 1 ATOM 2712 O O . SER B 2 91 ? -56.117 2.137 75.026 1.00 80.81 ? 91 SER L O 1 ATOM 2713 C CB . SER B 2 91 ? -56.895 2.375 72.355 1.00 79.65 ? 91 SER L CB 1 ATOM 2714 O OG . SER B 2 91 ? -56.085 3.533 72.254 1.00 79.94 ? 91 SER L OG 1 ATOM 2715 N N . ASN B 2 92 ? -57.764 3.510 75.705 1.00 79.35 ? 92 ASN L N 1 ATOM 2716 C CA . ASN B 2 92 ? -57.116 3.845 76.968 1.00 79.05 ? 92 ASN L CA 1 ATOM 2717 C C . ASN B 2 92 ? -57.156 2.677 77.942 1.00 79.21 ? 92 ASN L C 1 ATOM 2718 O O . ASN B 2 92 ? -56.160 2.370 78.594 1.00 79.66 ? 92 ASN L O 1 ATOM 2719 C CB . ASN B 2 92 ? -57.779 5.066 77.601 1.00 78.92 ? 92 ASN L CB 1 ATOM 2720 C CG . ASN B 2 92 ? -56.948 5.663 78.714 1.00 79.06 ? 92 ASN L CG 1 ATOM 2721 O OD1 . ASN B 2 92 ? -57.382 5.730 79.864 1.00 79.48 ? 92 ASN L OD1 1 ATOM 2722 N ND2 . ASN B 2 92 ? -55.740 6.091 78.381 1.00 78.96 ? 92 ASN L ND2 1 ATOM 2723 N N . VAL B 2 93 ? -58.320 2.041 78.041 1.00 79.00 ? 93 VAL L N 1 ATOM 2724 C CA . VAL B 2 93 ? -58.507 0.873 78.897 1.00 78.77 ? 93 VAL L CA 1 ATOM 2725 C C . VAL B 2 93 ? -59.505 -0.074 78.239 1.00 79.13 ? 93 VAL L C 1 ATOM 2726 O O . VAL B 2 93 ? -60.479 0.372 77.629 1.00 80.66 ? 93 VAL L O 1 ATOM 2727 C CB . VAL B 2 93 ? -59.016 1.278 80.304 1.00 79.19 ? 93 VAL L CB 1 ATOM 2728 C CG1 . VAL B 2 93 ? -60.337 2.021 80.202 1.00 79.65 ? 93 VAL L CG1 1 ATOM 2729 C CG2 . VAL B 2 93 ? -59.154 0.057 81.205 1.00 79.21 ? 93 VAL L CG2 1 ATOM 2730 N N . TRP B 2 94 ? -59.254 -1.376 78.350 1.00 77.93 ? 94 TRP L N 1 ATOM 2731 C CA . TRP B 2 94 ? -60.147 -2.379 77.772 1.00 77.31 ? 94 TRP L CA 1 ATOM 2732 C C . TRP B 2 94 ? -61.415 -2.494 78.622 1.00 76.82 ? 94 TRP L C 1 ATOM 2733 O O . TRP B 2 94 ? -61.362 -2.308 79.836 1.00 77.41 ? 94 TRP L O 1 ATOM 2734 C CB . TRP B 2 94 ? -59.450 -3.737 77.686 1.00 76.37 ? 94 TRP L CB 1 ATOM 2735 C CG . TRP B 2 94 ? -58.346 -3.804 76.667 1.00 76.34 ? 94 TRP L CG 1 ATOM 2736 C CD1 . TRP B 2 94 ? -57.653 -2.755 76.123 1.00 76.34 ? 94 TRP L CD1 1 ATOM 2737 C CD2 . TRP B 2 94 ? -57.783 -4.990 76.098 1.00 75.94 ? 94 TRP L CD2 1 ATOM 2738 N NE1 . TRP B 2 94 ? -56.708 -3.219 75.243 1.00 76.22 ? 94 TRP L NE1 1 ATOM 2739 C CE2 . TRP B 2 94 ? -56.766 -4.586 75.209 1.00 75.90 ? 94 TRP L CE2 1 ATOM 2740 C CE3 . TRP B 2 94 ? -58.044 -6.355 76.249 1.00 76.14 ? 94 TRP L CE3 1 ATOM 2741 C CZ2 . TRP B 2 94 ? -56.009 -5.498 74.473 1.00 76.18 ? 94 TRP L CZ2 1 ATOM 2742 C CZ3 . TRP B 2 94 ? -57.289 -7.261 75.517 1.00 76.37 ? 94 TRP L CZ3 1 ATOM 2743 C CH2 . TRP B 2 94 ? -56.285 -6.827 74.639 1.00 76.31 ? 94 TRP L CH2 1 ATOM 2744 N N . PRO B 2 95 ? -62.560 -2.806 77.993 1.00 76.68 ? 95 PRO L N 1 ATOM 2745 C CA . PRO B 2 95 ? -62.743 -3.113 76.578 1.00 76.64 ? 95 PRO L CA 1 ATOM 2746 C C . PRO B 2 95 ? -62.702 -1.875 75.696 1.00 76.64 ? 95 PRO L C 1 ATOM 2747 O O . PRO B 2 95 ? -63.043 -0.781 76.146 1.00 76.30 ? 95 PRO L O 1 ATOM 2748 C CB . PRO B 2 95 ? -64.141 -3.724 76.540 1.00 76.43 ? 95 PRO L CB 1 ATOM 2749 C CG . PRO B 2 95 ? -64.857 -3.054 77.637 1.00 76.62 ? 95 PRO L CG 1 ATOM 2750 C CD . PRO B 2 95 ? -63.838 -2.861 78.725 1.00 77.00 ? 95 PRO L CD 1 ATOM 2751 N N . PHE B 2 96 ? -62.278 -2.057 74.449 1.00 77.16 ? 96 PHE L N 1 ATOM 2752 C CA . PHE B 2 96 ? -62.346 -0.996 73.455 1.00 76.87 ? 96 PHE L CA 1 ATOM 2753 C C . PHE B 2 96 ? -63.802 -0.634 73.251 1.00 76.36 ? 96 PHE L C 1 ATOM 2754 O O . PHE B 2 96 ? -64.658 -1.513 73.174 1.00 75.76 ? 96 PHE L O 1 ATOM 2755 C CB . PHE B 2 96 ? -61.777 -1.461 72.121 1.00 78.00 ? 96 PHE L CB 1 ATOM 2756 C CG . PHE B 2 96 ? -60.306 -1.701 72.138 1.00 78.08 ? 96 PHE L CG 1 ATOM 2757 C CD1 . PHE B 2 96 ? -59.424 -0.680 71.822 1.00 78.23 ? 96 PHE L CD1 1 ATOM 2758 C CD2 . PHE B 2 96 ? -59.799 -2.955 72.440 1.00 77.95 ? 96 PHE L CD2 1 ATOM 2759 C CE1 . PHE B 2 96 ? -58.064 -0.901 71.821 1.00 78.28 ? 96 PHE L CE1 1 ATOM 2760 C CE2 . PHE B 2 96 ? -58.438 -3.183 72.441 1.00 78.07 ? 96 PHE L CE2 1 ATOM 2761 C CZ . PHE B 2 96 ? -57.569 -2.154 72.130 1.00 78.33 ? 96 PHE L CZ 1 ATOM 2762 N N . THR B 2 97 ? -64.080 0.660 73.158 1.00 76.59 ? 97 THR L N 1 ATOM 2763 C CA . THR B 2 97 ? -65.439 1.130 72.943 1.00 76.84 ? 97 THR L CA 1 ATOM 2764 C C . THR B 2 97 ? -65.472 2.120 71.790 1.00 76.96 ? 97 THR L C 1 ATOM 2765 O O . THR B 2 97 ? -64.515 2.859 71.574 1.00 76.70 ? 97 THR L O 1 ATOM 2766 C CB . THR B 2 97 ? -66.002 1.782 74.210 1.00 75.40 ? 97 THR L CB 1 ATOM 2767 O OG1 . THR B 2 97 ? -65.042 2.703 74.737 1.00 75.58 ? 97 THR L OG1 1 ATOM 2768 C CG2 . THR B 2 97 ? -66.307 0.724 75.255 1.00 74.33 ? 97 THR L CG2 1 ATOM 2769 N N . PHE B 2 98 ? -66.578 2.110 71.048 1.00 77.37 ? 98 PHE L N 1 ATOM 2770 C CA . PHE B 2 98 ? -66.763 2.984 69.896 1.00 77.34 ? 98 PHE L CA 1 ATOM 2771 C C . PHE B 2 98 ? -67.838 4.015 70.201 1.00 77.79 ? 98 PHE L C 1 ATOM 2772 O O . PHE B 2 98 ? -68.638 3.834 71.116 1.00 77.79 ? 98 PHE L O 1 ATOM 2773 C CB . PHE B 2 98 ? -67.173 2.167 68.665 1.00 76.09 ? 98 PHE L CB 1 ATOM 2774 C CG . PHE B 2 98 ? -66.140 1.160 68.229 1.00 76.15 ? 98 PHE L CG 1 ATOM 2775 C CD1 . PHE B 2 98 ? -66.064 -0.088 68.838 1.00 76.05 ? 98 PHE L CD1 1 ATOM 2776 C CD2 . PHE B 2 98 ? -65.249 1.456 67.207 1.00 75.88 ? 98 PHE L CD2 1 ATOM 2777 C CE1 . PHE B 2 98 ? -65.115 -1.019 68.440 1.00 75.74 ? 98 PHE L CE1 1 ATOM 2778 C CE2 . PHE B 2 98 ? -64.298 0.527 66.803 1.00 75.91 ? 98 PHE L CE2 1 ATOM 2779 C CZ . PHE B 2 98 ? -64.233 -0.712 67.423 1.00 75.74 ? 98 PHE L CZ 1 ATOM 2780 N N . GLY B 2 99 ? -67.853 5.096 69.429 1.00 78.45 ? 99 GLY L N 1 ATOM 2781 C CA . GLY B 2 99 ? -68.885 6.117 69.560 1.00 78.37 ? 99 GLY L CA 1 ATOM 2782 C C . GLY B 2 99 ? -70.173 5.697 68.876 1.00 78.98 ? 99 GLY L C 1 ATOM 2783 O O . GLY B 2 99 ? -70.198 4.716 68.129 1.00 79.47 ? 99 GLY L O 1 ATOM 2784 N N . SER B 2 100 ? -71.244 6.443 69.134 1.00 79.15 ? 100 SER L N 1 ATOM 2785 C CA . SER B 2 100 ? -72.557 6.151 68.551 1.00 78.98 ? 100 SER L CA 1 ATOM 2786 C C . SER B 2 100 ? -72.563 6.315 67.031 1.00 79.38 ? 100 SER L C 1 ATOM 2787 O O . SER B 2 100 ? -73.368 5.689 66.340 1.00 80.55 ? 100 SER L O 1 ATOM 2788 C CB . SER B 2 100 ? -73.634 7.047 69.175 1.00 79.85 ? 100 SER L CB 1 ATOM 2789 O OG . SER B 2 100 ? -73.228 8.404 69.196 1.00 80.44 ? 100 SER L OG 1 ATOM 2790 N N . GLY B 2 101 ? -71.669 7.160 66.521 1.00 78.57 ? 101 GLY L N 1 ATOM 2791 C CA . GLY B 2 101 ? -71.495 7.335 65.082 1.00 78.00 ? 101 GLY L CA 1 ATOM 2792 C C . GLY B 2 101 ? -72.009 8.670 64.575 1.00 77.67 ? 101 GLY L C 1 ATOM 2793 O O . GLY B 2 101 ? -72.917 9.267 65.160 1.00 77.92 ? 101 GLY L O 1 ATOM 2794 N N . THR B 2 102 ? -71.406 9.142 63.488 1.00 76.84 ? 102 THR L N 1 ATOM 2795 C CA . THR B 2 102 ? -71.886 10.317 62.772 1.00 76.93 ? 102 THR L CA 1 ATOM 2796 C C . THR B 2 102 ? -71.961 9.976 61.294 1.00 76.76 ? 102 THR L C 1 ATOM 2797 O O . THR B 2 102 ? -71.040 9.367 60.747 1.00 76.29 ? 102 THR L O 1 ATOM 2798 C CB . THR B 2 102 ? -70.950 11.524 62.956 1.00 76.40 ? 102 THR L CB 1 ATOM 2799 O OG1 . THR B 2 102 ? -70.890 11.879 64.341 1.00 76.26 ? 102 THR L OG1 1 ATOM 2800 C CG2 . THR B 2 102 ? -71.443 12.722 62.149 1.00 76.25 ? 102 THR L CG2 1 ATOM 2801 N N . LYS B 2 103 ? -73.057 10.372 60.654 1.00 77.16 ? 103 LYS L N 1 ATOM 2802 C CA . LYS B 2 103 ? -73.274 10.097 59.239 1.00 77.08 ? 103 LYS L CA 1 ATOM 2803 C C . LYS B 2 103 ? -73.065 11.362 58.412 1.00 76.06 ? 103 LYS L C 1 ATOM 2804 O O . LYS B 2 103 ? -73.725 12.376 58.642 1.00 75.49 ? 103 LYS L O 1 ATOM 2805 C CB . LYS B 2 103 ? -74.687 9.563 59.027 1.00 77.83 ? 103 LYS L CB 1 ATOM 2806 C CG . LYS B 2 103 ? -74.989 9.160 57.599 1.00 77.67 ? 103 LYS L CG 1 ATOM 2807 C CD . LYS B 2 103 ? -76.260 8.344 57.533 1.00 78.08 ? 103 LYS L CD 1 ATOM 2808 C CE . LYS B 2 103 ? -76.698 8.123 56.104 1.00 78.80 ? 103 LYS L CE 1 ATOM 2809 N NZ . LYS B 2 103 ? -77.131 9.388 55.443 1.00 79.44 ? 103 LYS L NZ 1 ATOM 2810 N N . LEU B 2 104 ? -72.149 11.292 57.449 1.00 75.69 ? 104 LEU L N 1 ATOM 2811 C CA . LEU B 2 104 ? -71.871 12.417 56.568 1.00 76.02 ? 104 LEU L CA 1 ATOM 2812 C C . LEU B 2 104 ? -72.683 12.305 55.277 1.00 76.27 ? 104 LEU L C 1 ATOM 2813 O O . LEU B 2 104 ? -72.459 11.398 54.471 1.00 76.01 ? 104 LEU L O 1 ATOM 2814 C CB . LEU B 2 104 ? -70.377 12.479 56.246 1.00 75.86 ? 104 LEU L CB 1 ATOM 2815 C CG . LEU B 2 104 ? -69.890 13.750 55.547 1.00 75.83 ? 104 LEU L CG 1 ATOM 2816 C CD1 . LEU B 2 104 ? -70.103 14.962 56.436 1.00 75.80 ? 104 LEU L CD1 1 ATOM 2817 C CD2 . LEU B 2 104 ? -68.426 13.620 55.168 1.00 76.10 ? 104 LEU L CD2 1 ATOM 2818 N N . GLU B 2 105 ? -73.635 13.223 55.101 1.00 76.29 ? 105 GLU L N 1 ATOM 2819 C CA . GLU B 2 105 ? -74.407 13.335 53.861 1.00 76.21 ? 105 GLU L CA 1 ATOM 2820 C C . GLU B 2 105 ? -73.862 14.487 53.026 1.00 76.05 ? 105 GLU L C 1 ATOM 2821 O O . GLU B 2 105 ? -73.258 15.417 53.562 1.00 75.81 ? 105 GLU L O 1 ATOM 2822 C CB . GLU B 2 105 ? -75.886 13.590 54.164 1.00 76.73 ? 105 GLU L CB 1 ATOM 2823 C CG . GLU B 2 105 ? -76.615 12.419 54.807 1.00 76.72 ? 105 GLU L CG 1 ATOM 2824 C CD . GLU B 2 105 ? -78.055 12.752 55.183 0.50 76.44 ? 105 GLU L CD 1 ATOM 2825 O OE1 . GLU B 2 105 ? -78.511 13.881 54.896 0.50 76.05 ? 105 GLU L OE1 1 ATOM 2826 O OE2 . GLU B 2 105 ? -78.731 11.881 55.769 0.50 76.61 ? 105 GLU L OE2 1 ATOM 2827 N N . ILE B 2 106 ? -74.091 14.423 51.716 1.00 76.28 ? 106 ILE L N 1 ATOM 2828 C CA . ILE B 2 106 ? -73.605 15.440 50.784 1.00 76.29 ? 106 ILE L CA 1 ATOM 2829 C C . ILE B 2 106 ? -74.764 16.202 50.146 1.00 76.26 ? 106 ILE L C 1 ATOM 2830 O O . ILE B 2 106 ? -75.705 15.597 49.632 1.00 75.81 ? 106 ILE L O 1 ATOM 2831 C CB . ILE B 2 106 ? -72.749 14.808 49.669 1.00 76.07 ? 106 ILE L CB 1 ATOM 2832 C CG1 . ILE B 2 106 ? -71.391 14.377 50.225 1.00 76.20 ? 106 ILE L CG1 1 ATOM 2833 C CG2 . ILE B 2 106 ? -72.554 15.787 48.513 1.00 76.13 ? 106 ILE L CG2 1 ATOM 2834 C CD1 . ILE B 2 106 ? -70.451 15.531 50.518 1.00 76.50 ? 106 ILE L CD1 1 ATOM 2835 N N . LYS B 2 107 ? -74.684 17.531 50.182 1.00 76.84 ? 107 LYS L N 1 ATOM 2836 C CA . LYS B 2 107 ? -75.673 18.385 49.522 1.00 77.07 ? 107 LYS L CA 1 ATOM 2837 C C . LYS B 2 107 ? -75.360 18.512 48.037 1.00 76.99 ? 107 LYS L C 1 ATOM 2838 O O . LYS B 2 107 ? -74.204 18.406 47.622 1.00 76.59 ? 107 LYS L O 1 ATOM 2839 C CB . LYS B 2 107 ? -75.733 19.769 50.174 1.00 77.32 ? 107 LYS L CB 1 ATOM 2840 C CG . LYS B 2 107 ? -76.502 19.792 51.483 1.00 77.54 ? 107 LYS L CG 1 ATOM 2841 C CD . LYS B 2 107 ? -76.668 21.208 52.007 1.00 77.74 ? 107 LYS L CD 1 ATOM 2842 C CE . LYS B 2 107 ? -77.484 21.233 53.291 1.00 77.78 ? 107 LYS L CE 1 ATOM 2843 N NZ . LYS B 2 107 ? -77.638 22.614 53.821 1.00 77.68 ? 107 LYS L NZ 1 ATOM 2844 N N . ARG B 2 108 ? -76.402 18.748 47.246 1.00 77.33 ? 108 ARG L N 1 ATOM 2845 C CA . ARG B 2 108 ? -76.312 18.673 45.793 1.00 77.49 ? 108 ARG L CA 1 ATOM 2846 C C . ARG B 2 108 ? -77.395 19.543 45.161 1.00 77.91 ? 108 ARG L C 1 ATOM 2847 O O . ARG B 2 108 ? -78.375 19.901 45.819 1.00 77.71 ? 108 ARG L O 1 ATOM 2848 C CB . ARG B 2 108 ? -76.496 17.214 45.354 1.00 77.14 ? 108 ARG L CB 1 ATOM 2849 C CG . ARG B 2 108 ? -76.016 16.891 43.944 1.00 77.36 ? 108 ARG L CG 1 ATOM 2850 C CD . ARG B 2 108 ? -76.926 15.869 43.275 1.00 77.07 ? 108 ARG L CD 1 ATOM 2851 N NE . ARG B 2 108 ? -76.488 15.521 41.923 1.00 76.71 ? 108 ARG L NE 1 ATOM 2852 C CZ . ARG B 2 108 ? -76.644 16.287 40.844 1.00 76.38 ? 108 ARG L CZ 1 ATOM 2853 N NH1 . ARG B 2 108 ? -76.206 15.855 39.668 1.00 76.78 ? 108 ARG L NH1 1 ATOM 2854 N NH2 . ARG B 2 108 ? -77.225 17.478 40.925 1.00 76.41 ? 108 ARG L NH2 1 ATOM 2855 N N . ALA B 2 109 ? -77.210 19.895 43.891 1.00 78.58 ? 109 ALA L N 1 ATOM 2856 C CA . ALA B 2 109 ? -78.256 20.560 43.116 1.00 78.76 ? 109 ALA L CA 1 ATOM 2857 C C . ALA B 2 109 ? -79.395 19.585 42.831 1.00 79.90 ? 109 ALA L C 1 ATOM 2858 O O . ALA B 2 109 ? -79.237 18.372 42.982 1.00 80.84 ? 109 ALA L O 1 ATOM 2859 C CB . ALA B 2 109 ? -77.688 21.107 41.818 1.00 77.96 ? 109 ALA L CB 1 ATOM 2860 N N . ASP B 2 110 ? -80.545 20.115 42.430 1.00 79.65 ? 110 ASP L N 1 ATOM 2861 C CA . ASP B 2 110 ? -81.700 19.272 42.139 1.00 79.45 ? 110 ASP L CA 1 ATOM 2862 C C . ASP B 2 110 ? -81.529 18.582 40.789 1.00 79.81 ? 110 ASP L C 1 ATOM 2863 O O . ASP B 2 110 ? -81.027 19.182 39.835 1.00 80.31 ? 110 ASP L O 1 ATOM 2864 C CB . ASP B 2 110 ? -82.992 20.092 42.154 1.00 80.95 ? 110 ASP L CB 1 ATOM 2865 C CG . ASP B 2 110 ? -83.330 20.633 43.536 1.00 82.77 ? 110 ASP L CG 1 ATOM 2866 O OD1 . ASP B 2 110 ? -82.935 20.010 44.548 1.00 82.85 ? 110 ASP L OD1 1 ATOM 2867 O OD2 . ASP B 2 110 ? -84.002 21.684 43.610 1.00 83.87 ? 110 ASP L OD2 1 ATOM 2868 N N . ALA B 2 111 ? -81.934 17.315 40.729 1.00 79.20 ? 111 ALA L N 1 ATOM 2869 C CA . ALA B 2 111 ? -81.906 16.541 39.491 1.00 78.16 ? 111 ALA L CA 1 ATOM 2870 C C . ALA B 2 111 ? -83.159 15.676 39.399 1.00 78.01 ? 111 ALA L C 1 ATOM 2871 O O . ALA B 2 111 ? -83.505 14.976 40.352 1.00 77.88 ? 111 ALA L O 1 ATOM 2872 C CB . ALA B 2 111 ? -80.664 15.677 39.441 1.00 77.26 ? 111 ALA L CB 1 ATOM 2873 N N . ALA B 2 112 ? -83.842 15.738 38.256 1.00 77.95 ? 112 ALA L N 1 ATOM 2874 C CA . ALA B 2 112 ? -85.080 14.985 38.050 1.00 77.43 ? 112 ALA L CA 1 ATOM 2875 C C . ALA B 2 112 ? -84.775 13.510 37.798 1.00 77.42 ? 112 ALA L C 1 ATOM 2876 O O . ALA B 2 112 ? -83.738 13.183 37.222 1.00 78.04 ? 112 ALA L O 1 ATOM 2877 C CB . ALA B 2 112 ? -85.861 15.566 36.886 1.00 76.78 ? 112 ALA L CB 1 ATOM 2878 N N . PRO B 2 113 ? -85.680 12.612 38.226 1.00 77.14 ? 113 PRO L N 1 ATOM 2879 C CA . PRO B 2 113 ? -85.461 11.177 38.055 1.00 77.13 ? 113 PRO L CA 1 ATOM 2880 C C . PRO B 2 113 ? -85.760 10.693 36.635 1.00 77.45 ? 113 PRO L C 1 ATOM 2881 O O . PRO B 2 113 ? -86.533 11.327 35.913 1.00 77.46 ? 113 PRO L O 1 ATOM 2882 C CB . PRO B 2 113 ? -86.452 10.557 39.042 1.00 76.84 ? 113 PRO L CB 1 ATOM 2883 C CG . PRO B 2 113 ? -87.567 11.530 39.106 1.00 76.90 ? 113 PRO L CG 1 ATOM 2884 C CD . PRO B 2 113 ? -86.964 12.895 38.896 1.00 77.09 ? 113 PRO L CD 1 ATOM 2885 N N . THR B 2 114 ? -85.140 9.580 36.247 1.00 77.34 ? 114 THR L N 1 ATOM 2886 C CA . THR B 2 114 ? -85.468 8.903 34.995 1.00 77.20 ? 114 THR L CA 1 ATOM 2887 C C . THR B 2 114 ? -86.381 7.719 35.309 1.00 77.22 ? 114 THR L C 1 ATOM 2888 O O . THR B 2 114 ? -85.913 6.642 35.686 1.00 77.33 ? 114 THR L O 1 ATOM 2889 C CB . THR B 2 114 ? -84.201 8.416 34.255 1.00 77.75 ? 114 THR L CB 1 ATOM 2890 O OG1 . THR B 2 114 ? -83.429 9.545 33.827 1.00 78.22 ? 114 THR L OG1 1 ATOM 2891 C CG2 . THR B 2 114 ? -84.575 7.580 33.036 1.00 77.56 ? 114 THR L CG2 1 ATOM 2892 N N . VAL B 2 115 ? -87.686 7.933 35.153 1.00 76.97 ? 115 VAL L N 1 ATOM 2893 C CA . VAL B 2 115 ? -88.686 6.936 35.527 1.00 76.33 ? 115 VAL L CA 1 ATOM 2894 C C . VAL B 2 115 ? -88.813 5.870 34.444 1.00 75.80 ? 115 VAL L C 1 ATOM 2895 O O . VAL B 2 115 ? -88.776 6.179 33.253 1.00 75.86 ? 115 VAL L O 1 ATOM 2896 C CB . VAL B 2 115 ? -90.072 7.580 35.772 1.00 75.73 ? 115 VAL L CB 1 ATOM 2897 C CG1 . VAL B 2 115 ? -91.046 6.547 36.328 1.00 75.53 ? 115 VAL L CG1 1 ATOM 2898 C CG2 . VAL B 2 115 ? -89.953 8.764 36.725 1.00 75.24 ? 115 VAL L CG2 1 ATOM 2899 N N . SER B 2 116 ? -88.956 4.616 34.869 1.00 75.71 ? 116 SER L N 1 ATOM 2900 C CA . SER B 2 116 ? -89.108 3.491 33.949 1.00 76.08 ? 116 SER L CA 1 ATOM 2901 C C . SER B 2 116 ? -90.040 2.441 34.543 1.00 76.30 ? 116 SER L C 1 ATOM 2902 O O . SER B 2 116 ? -89.797 1.950 35.644 1.00 76.48 ? 116 SER L O 1 ATOM 2903 C CB . SER B 2 116 ? -87.749 2.857 33.655 1.00 76.40 ? 116 SER L CB 1 ATOM 2904 O OG . SER B 2 116 ? -86.892 3.771 32.996 1.00 76.84 ? 116 SER L OG 1 ATOM 2905 N N . ILE B 2 117 ? -91.104 2.108 33.812 1.00 76.06 ? 117 ILE L N 1 ATOM 2906 C CA . ILE B 2 117 ? -92.069 1.096 34.248 1.00 75.52 ? 117 ILE L CA 1 ATOM 2907 C C . ILE B 2 117 ? -91.826 -0.214 33.501 1.00 75.18 ? 117 ILE L C 1 ATOM 2908 O O . ILE B 2 117 ? -91.368 -0.207 32.357 1.00 75.17 ? 117 ILE L O 1 ATOM 2909 C CB . ILE B 2 117 ? -93.529 1.572 34.030 1.00 75.26 ? 117 ILE L CB 1 ATOM 2910 C CG1 . ILE B 2 117 ? -94.510 0.682 34.800 1.00 75.11 ? 117 ILE L CG1 1 ATOM 2911 C CG2 . ILE B 2 117 ? -93.878 1.600 32.545 1.00 75.22 ? 117 ILE L CG2 1 ATOM 2912 C CD1 . ILE B 2 117 ? -95.926 1.216 34.821 1.00 75.26 ? 117 ILE L CD1 1 ATOM 2913 N N . PHE B 2 118 ? -92.123 -1.333 34.161 1.00 75.31 ? 118 PHE L N 1 ATOM 2914 C CA . PHE B 2 118 ? -91.881 -2.665 33.600 1.00 75.23 ? 118 PHE L CA 1 ATOM 2915 C C . PHE B 2 118 ? -93.057 -3.604 33.882 1.00 75.00 ? 118 PHE L C 1 ATOM 2916 O O . PHE B 2 118 ? -93.536 -3.669 35.015 1.00 74.85 ? 118 PHE L O 1 ATOM 2917 C CB . PHE B 2 118 ? -90.605 -3.266 34.194 1.00 74.85 ? 118 PHE L CB 1 ATOM 2918 C CG . PHE B 2 118 ? -89.369 -2.460 33.918 1.00 74.58 ? 118 PHE L CG 1 ATOM 2919 C CD1 . PHE B 2 118 ? -88.566 -2.748 32.825 1.00 74.59 ? 118 PHE L CD1 1 ATOM 2920 C CD2 . PHE B 2 118 ? -89.007 -1.412 34.754 1.00 74.81 ? 118 PHE L CD2 1 ATOM 2921 C CE1 . PHE B 2 118 ? -87.423 -2.006 32.567 1.00 74.78 ? 118 PHE L CE1 1 ATOM 2922 C CE2 . PHE B 2 118 ? -87.868 -0.663 34.501 1.00 74.95 ? 118 PHE L CE2 1 ATOM 2923 C CZ . PHE B 2 118 ? -87.073 -0.960 33.407 1.00 74.89 ? 118 PHE L CZ 1 ATOM 2924 N N . PRO B 2 119 ? -93.531 -4.334 32.853 1.00 75.10 ? 119 PRO L N 1 ATOM 2925 C CA . PRO B 2 119 ? -94.566 -5.338 33.101 1.00 75.11 ? 119 PRO L CA 1 ATOM 2926 C C . PRO B 2 119 ? -94.012 -6.591 33.784 1.00 74.86 ? 119 PRO L C 1 ATOM 2927 O O . PRO B 2 119 ? -92.795 -6.777 33.827 1.00 74.66 ? 119 PRO L O 1 ATOM 2928 C CB . PRO B 2 119 ? -95.068 -5.695 31.690 1.00 75.04 ? 119 PRO L CB 1 ATOM 2929 C CG . PRO B 2 119 ? -94.409 -4.732 30.753 1.00 75.10 ? 119 PRO L CG 1 ATOM 2930 C CD . PRO B 2 119 ? -93.172 -4.268 31.428 1.00 75.18 ? 119 PRO L CD 1 ATOM 2931 N N . PRO B 2 120 ? -94.901 -7.446 34.322 1.00 75.12 ? 120 PRO L N 1 ATOM 2932 C CA . PRO B 2 120 ? -94.492 -8.778 34.774 1.00 75.37 ? 120 PRO L CA 1 ATOM 2933 C C . PRO B 2 120 ? -94.062 -9.663 33.605 1.00 75.55 ? 120 PRO L C 1 ATOM 2934 O O . PRO B 2 120 ? -94.704 -9.649 32.552 1.00 75.83 ? 120 PRO L O 1 ATOM 2935 C CB . PRO B 2 120 ? -95.764 -9.345 35.426 1.00 75.35 ? 120 PRO L CB 1 ATOM 2936 C CG . PRO B 2 120 ? -96.674 -8.184 35.620 1.00 75.45 ? 120 PRO L CG 1 ATOM 2937 C CD . PRO B 2 120 ? -96.334 -7.203 34.557 1.00 75.32 ? 120 PRO L CD 1 ATOM 2938 N N . SER B 2 121 ? -92.988 -10.425 33.793 1.00 75.58 ? 121 SER L N 1 ATOM 2939 C CA . SER B 2 121 ? -92.473 -11.301 32.742 1.00 75.66 ? 121 SER L CA 1 ATOM 2940 C C . SER B 2 121 ? -93.371 -12.518 32.548 1.00 75.81 ? 121 SER L C 1 ATOM 2941 O O . SER B 2 121 ? -94.207 -12.831 33.399 1.00 75.88 ? 121 SER L O 1 ATOM 2942 C CB . SER B 2 121 ? -91.056 -11.761 33.079 1.00 75.60 ? 121 SER L CB 1 ATOM 2943 O OG . SER B 2 121 ? -91.051 -12.600 34.221 1.00 75.69 ? 121 SER L OG 1 ATOM 2944 N N . SER B 2 122 ? -93.183 -13.206 31.426 1.00 75.86 ? 122 SER L N 1 ATOM 2945 C CA . SER B 2 122 ? -93.932 -14.426 31.129 1.00 76.02 ? 122 SER L CA 1 ATOM 2946 C C . SER B 2 122 ? -93.626 -15.543 32.132 1.00 76.11 ? 122 SER L C 1 ATOM 2947 O O . SER B 2 122 ? -94.450 -16.434 32.344 1.00 76.02 ? 122 SER L O 1 ATOM 2948 C CB . SER B 2 122 ? -93.630 -14.903 29.707 1.00 76.00 ? 122 SER L CB 1 ATOM 2949 O OG . SER B 2 122 ? -92.238 -15.083 29.515 1.00 75.98 ? 122 SER L OG 1 ATOM 2950 N N . GLU B 2 123 ? -92.442 -15.489 32.743 1.00 76.30 ? 123 GLU L N 1 ATOM 2951 C CA . GLU B 2 123 ? -92.051 -16.457 33.769 1.00 76.59 ? 123 GLU L CA 1 ATOM 2952 C C . GLU B 2 123 ? -92.910 -16.314 35.023 1.00 76.36 ? 123 GLU L C 1 ATOM 2953 O O . GLU B 2 123 ? -93.431 -17.302 35.542 1.00 76.54 ? 123 GLU L O 1 ATOM 2954 C CB . GLU B 2 123 ? -90.574 -16.288 34.150 1.00 77.73 ? 123 GLU L CB 1 ATOM 2955 C CG . GLU B 2 123 ? -89.582 -16.653 33.049 1.00 78.77 ? 123 GLU L CG 1 ATOM 2956 C CD . GLU B 2 123 ? -89.159 -15.458 32.214 1.00 79.48 ? 123 GLU L CD 1 ATOM 2957 O OE1 . GLU B 2 123 ? -90.046 -14.755 31.685 1.00 79.76 ? 123 GLU L OE1 1 ATOM 2958 O OE2 . GLU B 2 123 ? -87.937 -15.224 32.084 1.00 79.64 ? 123 GLU L OE2 1 ATOM 2959 N N . GLN B 2 124 ? -93.051 -15.082 35.503 1.00 76.04 ? 124 GLN L N 1 ATOM 2960 C CA . GLN B 2 124 ? -93.778 -14.815 36.743 1.00 76.30 ? 124 GLN L CA 1 ATOM 2961 C C . GLN B 2 124 ? -95.278 -15.078 36.604 1.00 76.23 ? 124 GLN L C 1 ATOM 2962 O O . GLN B 2 124 ? -95.925 -15.502 37.563 1.00 75.88 ? 124 GLN L O 1 ATOM 2963 C CB . GLN B 2 124 ? -93.544 -13.374 37.203 1.00 76.00 ? 124 GLN L CB 1 ATOM 2964 C CG . GLN B 2 124 ? -94.035 -13.096 38.615 1.00 75.85 ? 124 GLN L CG 1 ATOM 2965 C CD . GLN B 2 124 ? -93.709 -11.697 39.088 1.00 75.81 ? 124 GLN L CD 1 ATOM 2966 O OE1 . GLN B 2 124 ? -93.588 -10.766 38.289 1.00 75.25 ? 124 GLN L OE1 1 ATOM 2967 N NE2 . GLN B 2 124 ? -93.578 -11.536 40.398 1.00 75.93 ? 124 GLN L NE2 1 ATOM 2968 N N . LEU B 2 125 ? -95.822 -14.824 35.416 1.00 76.78 ? 125 LEU L N 1 ATOM 2969 C CA . LEU B 2 125 ? -97.244 -15.058 35.148 1.00 77.43 ? 125 LEU L CA 1 ATOM 2970 C C . LEU B 2 125 ? -97.611 -16.545 35.185 1.00 77.97 ? 125 LEU L C 1 ATOM 2971 O O . LEU B 2 125 ? -98.757 -16.896 35.468 1.00 78.32 ? 125 LEU L O 1 ATOM 2972 C CB . LEU B 2 125 ? -97.642 -14.459 33.795 1.00 77.97 ? 125 LEU L CB 1 ATOM 2973 C CG . LEU B 2 125 ? -97.630 -12.930 33.712 1.00 78.23 ? 125 LEU L CG 1 ATOM 2974 C CD1 . LEU B 2 125 ? -97.819 -12.468 32.274 1.00 78.23 ? 125 LEU L CD1 1 ATOM 2975 C CD2 . LEU B 2 125 ? -98.701 -12.332 34.612 1.00 78.41 ? 125 LEU L CD2 1 ATOM 2976 N N . THR B 2 126 ? -96.642 -17.409 34.893 1.00 78.17 ? 126 THR L N 1 ATOM 2977 C CA . THR B 2 126 ? -96.845 -18.857 34.964 1.00 78.13 ? 126 THR L CA 1 ATOM 2978 C C . THR B 2 126 ? -96.975 -19.334 36.413 1.00 78.33 ? 126 THR L C 1 ATOM 2979 O O . THR B 2 126 ? -97.756 -20.240 36.707 1.00 78.37 ? 126 THR L O 1 ATOM 2980 C CB . THR B 2 126 ? -95.680 -19.619 34.297 1.00 78.20 ? 126 THR L CB 1 ATOM 2981 O OG1 . THR B 2 126 ? -95.421 -19.068 33.000 1.00 78.15 ? 126 THR L OG1 1 ATOM 2982 C CG2 . THR B 2 126 ? -96.009 -21.102 34.164 1.00 78.24 ? 126 THR L CG2 1 ATOM 2983 N N . SER B 2 127 ? -96.211 -18.711 37.310 1.00 78.39 ? 127 SER L N 1 ATOM 2984 C CA . SER B 2 127 ? -96.170 -19.105 38.721 1.00 78.50 ? 127 SER L CA 1 ATOM 2985 C C . SER B 2 127 ? -97.417 -18.699 39.519 1.00 78.61 ? 127 SER L C 1 ATOM 2986 O O . SER B 2 127 ? -97.641 -19.210 40.617 1.00 78.75 ? 127 SER L O 1 ATOM 2987 C CB . SER B 2 127 ? -94.926 -18.513 39.392 1.00 79.21 ? 127 SER L CB 1 ATOM 2988 O OG . SER B 2 127 ? -94.854 -18.882 40.758 1.00 79.73 ? 127 SER L OG 1 ATOM 2989 N N . GLY B 2 128 ? -98.212 -17.777 38.977 1.00 78.47 ? 128 GLY L N 1 ATOM 2990 C CA . GLY B 2 128 ? -99.422 -17.298 39.651 1.00 78.11 ? 128 GLY L CA 1 ATOM 2991 C C . GLY B 2 128 ? -99.211 -16.014 40.439 1.00 77.87 ? 128 GLY L C 1 ATOM 2992 O O . GLY B 2 128 ? -99.904 -15.765 41.428 1.00 77.74 ? 128 GLY L O 1 ATOM 2993 N N . GLY B 2 129 ? -98.256 -15.198 39.996 1.00 77.56 ? 129 GLY L N 1 ATOM 2994 C CA . GLY B 2 129 ? -97.978 -13.901 40.612 1.00 77.51 ? 129 GLY L CA 1 ATOM 2995 C C . GLY B 2 129 ? -97.846 -12.825 39.554 1.00 77.37 ? 129 GLY L C 1 ATOM 2996 O O . GLY B 2 129 ? -97.695 -13.129 38.369 1.00 77.60 ? 129 GLY L O 1 ATOM 2997 N N . ALA B 2 130 ? -97.902 -11.565 39.979 1.00 77.15 ? 130 ALA L N 1 ATOM 2998 C CA . ALA B 2 130 ? -97.853 -10.436 39.049 1.00 77.25 ? 130 ALA L CA 1 ATOM 2999 C C . ALA B 2 130 ? -97.265 -9.189 39.704 1.00 77.56 ? 130 ALA L C 1 ATOM 3000 O O . ALA B 2 130 ? -97.992 -8.385 40.295 1.00 77.87 ? 130 ALA L O 1 ATOM 3001 C CB . ALA B 2 130 ? -99.242 -10.143 38.512 1.00 77.25 ? 130 ALA L CB 1 ATOM 3002 N N . SER B 2 131 ? -95.948 -9.034 39.586 1.00 77.15 ? 131 SER L N 1 ATOM 3003 C CA . SER B 2 131 ? -95.244 -7.883 40.141 1.00 76.93 ? 131 SER L CA 1 ATOM 3004 C C . SER B 2 131 ? -94.939 -6.862 39.047 1.00 75.90 ? 131 SER L C 1 ATOM 3005 O O . SER B 2 131 ? -94.372 -7.209 38.008 1.00 74.98 ? 131 SER L O 1 ATOM 3006 C CB . SER B 2 131 ? -93.943 -8.325 40.815 1.00 78.09 ? 131 SER L CB 1 ATOM 3007 O OG . SER B 2 131 ? -94.205 -9.119 41.959 1.00 78.95 ? 131 SER L OG 1 ATOM 3008 N N . VAL B 2 132 ? -95.320 -5.609 39.289 1.00 75.94 ? 132 VAL L N 1 ATOM 3009 C CA . VAL B 2 132 ? -95.026 -4.506 38.373 1.00 76.25 ? 132 VAL L CA 1 ATOM 3010 C C . VAL B 2 132 ? -93.954 -3.604 38.987 1.00 76.30 ? 132 VAL L C 1 ATOM 3011 O O . VAL B 2 132 ? -94.178 -2.982 40.028 1.00 76.23 ? 132 VAL L O 1 ATOM 3012 C CB . VAL B 2 132 ? -96.291 -3.669 38.069 1.00 74.66 ? 132 VAL L CB 1 ATOM 3013 C CG1 . VAL B 2 132 ? -95.984 -2.596 37.036 1.00 73.96 ? 132 VAL L CG1 1 ATOM 3014 C CG2 . VAL B 2 132 ? -97.418 -4.565 37.585 1.00 73.90 ? 132 VAL L CG2 1 ATOM 3015 N N . VAL B 2 133 ? -92.791 -3.546 38.341 1.00 76.49 ? 133 VAL L N 1 ATOM 3016 C CA . VAL B 2 133 ? -91.650 -2.784 38.849 1.00 77.06 ? 133 VAL L CA 1 ATOM 3017 C C . VAL B 2 133 ? -91.599 -1.393 38.221 1.00 77.66 ? 133 VAL L C 1 ATOM 3018 O O . VAL B 2 133 ? -92.001 -1.207 37.073 1.00 77.50 ? 133 VAL L O 1 ATOM 3019 C CB . VAL B 2 133 ? -90.320 -3.517 38.568 1.00 77.10 ? 133 VAL L CB 1 ATOM 3020 C CG1 . VAL B 2 133 ? -89.137 -2.715 39.101 1.00 77.01 ? 133 VAL L CG1 1 ATOM 3021 C CG2 . VAL B 2 133 ? -90.342 -4.907 39.182 1.00 77.11 ? 133 VAL L CG2 1 ATOM 3022 N N . CYS B 2 134 ? -91.100 -0.424 38.984 1.00 78.77 ? 134 CYS L N 1 ATOM 3023 C CA . CYS B 2 134 ? -90.976 0.955 38.517 1.00 77.76 ? 134 CYS L CA 1 ATOM 3024 C C . CYS B 2 134 ? -89.722 1.609 39.107 1.00 76.95 ? 134 CYS L C 1 ATOM 3025 O O . CYS B 2 134 ? -89.714 2.007 40.272 1.00 76.90 ? 134 CYS L O 1 ATOM 3026 C CB . CYS B 2 134 ? -92.230 1.746 38.900 1.00 79.34 ? 134 CYS L CB 1 ATOM 3027 S SG . CYS B 2 134 ? -92.232 3.494 38.428 1.00 80.68 ? 134 CYS L SG 1 ATOM 3028 N N . PHE B 2 135 ? -88.663 1.699 38.302 1.00 76.27 ? 135 PHE L N 1 ATOM 3029 C CA . PHE B 2 135 ? -87.419 2.338 38.727 1.00 76.28 ? 135 PHE L CA 1 ATOM 3030 C C . PHE B 2 135 ? -87.481 3.849 38.532 1.00 76.67 ? 135 PHE L C 1 ATOM 3031 O O . PHE B 2 135 ? -88.054 4.332 37.557 1.00 77.47 ? 135 PHE L O 1 ATOM 3032 C CB . PHE B 2 135 ? -86.220 1.794 37.943 1.00 75.72 ? 135 PHE L CB 1 ATOM 3033 C CG . PHE B 2 135 ? -85.930 0.339 38.190 1.00 75.74 ? 135 PHE L CG 1 ATOM 3034 C CD1 . PHE B 2 135 ? -85.872 -0.171 39.480 1.00 75.83 ? 135 PHE L CD1 1 ATOM 3035 C CD2 . PHE B 2 135 ? -85.679 -0.516 37.126 1.00 75.78 ? 135 PHE L CD2 1 ATOM 3036 C CE1 . PHE B 2 135 ? -85.594 -1.512 39.699 1.00 75.82 ? 135 PHE L CE1 1 ATOM 3037 C CE2 . PHE B 2 135 ? -85.399 -1.853 37.339 1.00 75.63 ? 135 PHE L CE2 1 ATOM 3038 C CZ . PHE B 2 135 ? -85.356 -2.353 38.626 1.00 75.82 ? 135 PHE L CZ 1 ATOM 3039 N N . LEU B 2 136 ? -86.886 4.580 39.473 1.00 76.11 ? 136 LEU L N 1 ATOM 3040 C CA . LEU B 2 136 ? -86.685 6.022 39.354 1.00 75.87 ? 136 LEU L CA 1 ATOM 3041 C C . LEU B 2 136 ? -85.229 6.320 39.709 1.00 75.78 ? 136 LEU L C 1 ATOM 3042 O O . LEU B 2 136 ? -84.851 6.272 40.879 1.00 75.79 ? 136 LEU L O 1 ATOM 3043 C CB . LEU B 2 136 ? -87.630 6.779 40.291 1.00 75.66 ? 136 LEU L CB 1 ATOM 3044 C CG . LEU B 2 136 ? -89.125 6.486 40.127 1.00 75.95 ? 136 LEU L CG 1 ATOM 3045 C CD1 . LEU B 2 136 ? -89.508 5.193 40.827 1.00 76.20 ? 136 LEU L CD1 1 ATOM 3046 C CD2 . LEU B 2 136 ? -89.957 7.634 40.665 1.00 75.92 ? 136 LEU L CD2 1 ATOM 3047 N N . ASN B 2 137 ? -84.413 6.613 38.697 1.00 75.86 ? 137 ASN L N 1 ATOM 3048 C CA . ASN B 2 137 ? -82.958 6.654 38.863 1.00 76.02 ? 137 ASN L CA 1 ATOM 3049 C C . ASN B 2 137 ? -82.348 8.056 38.807 1.00 76.02 ? 137 ASN L C 1 ATOM 3050 O O . ASN B 2 137 ? -82.818 8.924 38.069 1.00 76.15 ? 137 ASN L O 1 ATOM 3051 C CB . ASN B 2 137 ? -82.290 5.766 37.806 1.00 76.43 ? 137 ASN L CB 1 ATOM 3052 C CG . ASN B 2 137 ? -82.571 4.283 38.018 1.00 77.12 ? 137 ASN L CG 1 ATOM 3053 O OD1 . ASN B 2 137 ? -83.036 3.868 39.081 1.00 77.52 ? 137 ASN L OD1 1 ATOM 3054 N ND2 . ASN B 2 137 ? -82.280 3.478 37.004 1.00 77.34 ? 137 ASN L ND2 1 ATOM 3055 N N . ASN B 2 138 ? -81.297 8.256 39.603 1.00 76.06 ? 138 ASN L N 1 ATOM 3056 C CA . ASN B 2 138 ? -80.468 9.466 39.562 1.00 75.87 ? 138 ASN L CA 1 ATOM 3057 C C . ASN B 2 138 ? -81.233 10.765 39.815 1.00 75.23 ? 138 ASN L C 1 ATOM 3058 O O . ASN B 2 138 ? -81.374 11.600 38.919 1.00 75.28 ? 138 ASN L O 1 ATOM 3059 C CB . ASN B 2 138 ? -79.711 9.545 38.231 1.00 76.60 ? 138 ASN L CB 1 ATOM 3060 C CG . ASN B 2 138 ? -78.847 8.330 37.983 1.00 77.30 ? 138 ASN L CG 1 ATOM 3061 O OD1 . ASN B 2 138 ? -79.015 7.628 36.988 1.00 77.67 ? 138 ASN L OD1 1 ATOM 3062 N ND2 . ASN B 2 138 ? -77.921 8.065 38.899 1.00 77.72 ? 138 ASN L ND2 1 ATOM 3063 N N . PHE B 2 139 ? -81.710 10.933 41.044 1.00 74.58 ? 139 PHE L N 1 ATOM 3064 C CA . PHE B 2 139 ? -82.411 12.150 41.429 1.00 74.99 ? 139 PHE L CA 1 ATOM 3065 C C . PHE B 2 139 ? -81.920 12.701 42.763 1.00 75.73 ? 139 PHE L C 1 ATOM 3066 O O . PHE B 2 139 ? -81.342 11.978 43.575 1.00 76.28 ? 139 PHE L O 1 ATOM 3067 C CB . PHE B 2 139 ? -83.922 11.905 41.482 1.00 74.40 ? 139 PHE L CB 1 ATOM 3068 C CG . PHE B 2 139 ? -84.345 10.902 42.520 1.00 74.47 ? 139 PHE L CG 1 ATOM 3069 C CD1 . PHE B 2 139 ? -84.429 9.549 42.212 1.00 74.48 ? 139 PHE L CD1 1 ATOM 3070 C CD2 . PHE B 2 139 ? -84.676 11.314 43.805 1.00 74.21 ? 139 PHE L CD2 1 ATOM 3071 C CE1 . PHE B 2 139 ? -84.829 8.623 43.177 1.00 74.42 ? 139 PHE L CE1 1 ATOM 3072 C CE2 . PHE B 2 139 ? -85.075 10.397 44.770 1.00 74.09 ? 139 PHE L CE2 1 ATOM 3073 C CZ . PHE B 2 139 ? -85.152 9.051 44.456 1.00 74.25 ? 139 PHE L CZ 1 ATOM 3074 N N . TYR B 2 140 ? -82.143 13.997 42.962 1.00 75.89 ? 140 TYR L N 1 ATOM 3075 C CA . TYR B 2 140 ? -81.886 14.658 44.236 1.00 75.58 ? 140 TYR L CA 1 ATOM 3076 C C . TYR B 2 140 ? -82.890 15.802 44.388 1.00 75.09 ? 140 TYR L C 1 ATOM 3077 O O . TYR B 2 140 ? -83.175 16.498 43.413 1.00 74.25 ? 140 TYR L O 1 ATOM 3078 C CB . TYR B 2 140 ? -80.456 15.201 44.283 1.00 76.26 ? 140 TYR L CB 1 ATOM 3079 C CG . TYR B 2 140 ? -80.072 15.759 45.632 1.00 76.11 ? 140 TYR L CG 1 ATOM 3080 C CD1 . TYR B 2 140 ? -80.368 17.075 45.972 1.00 76.10 ? 140 TYR L CD1 1 ATOM 3081 C CD2 . TYR B 2 140 ? -79.432 14.966 46.577 1.00 76.26 ? 140 TYR L CD2 1 ATOM 3082 C CE1 . TYR B 2 140 ? -80.030 17.589 47.213 1.00 76.33 ? 140 TYR L CE1 1 ATOM 3083 C CE2 . TYR B 2 140 ? -79.088 15.471 47.823 1.00 76.41 ? 140 TYR L CE2 1 ATOM 3084 C CZ . TYR B 2 140 ? -79.389 16.785 48.134 1.00 76.42 ? 140 TYR L CZ 1 ATOM 3085 O OH . TYR B 2 140 ? -79.054 17.293 49.367 1.00 76.38 ? 140 TYR L OH 1 ATOM 3086 N N . PRO B 2 141 ? -83.424 16.014 45.607 1.00 75.49 ? 141 PRO L N 1 ATOM 3087 C CA . PRO B 2 141 ? -83.129 15.348 46.875 1.00 75.80 ? 141 PRO L CA 1 ATOM 3088 C C . PRO B 2 141 ? -83.802 13.992 47.015 1.00 75.71 ? 141 PRO L C 1 ATOM 3089 O O . PRO B 2 141 ? -84.584 13.598 46.154 1.00 75.49 ? 141 PRO L O 1 ATOM 3090 C CB . PRO B 2 141 ? -83.691 16.324 47.906 1.00 75.97 ? 141 PRO L CB 1 ATOM 3091 C CG . PRO B 2 141 ? -84.846 16.940 47.224 1.00 75.70 ? 141 PRO L CG 1 ATOM 3092 C CD . PRO B 2 141 ? -84.470 17.040 45.772 1.00 75.63 ? 141 PRO L CD 1 ATOM 3093 N N . LYS B 2 142 ? -83.495 13.299 48.110 1.00 76.53 ? 142 LYS L N 1 ATOM 3094 C CA . LYS B 2 142 ? -83.977 11.937 48.351 1.00 76.45 ? 142 LYS L CA 1 ATOM 3095 C C . LYS B 2 142 ? -85.499 11.850 48.417 1.00 76.00 ? 142 LYS L C 1 ATOM 3096 O O . LYS B 2 142 ? -86.082 10.869 47.961 1.00 75.61 ? 142 LYS L O 1 ATOM 3097 C CB . LYS B 2 142 ? -83.375 11.386 49.652 1.00 76.72 ? 142 LYS L CB 1 ATOM 3098 C CG . LYS B 2 142 ? -83.776 9.946 49.974 1.00 76.98 ? 142 LYS L CG 1 ATOM 3099 C CD . LYS B 2 142 ? -83.090 9.434 51.233 1.00 76.82 ? 142 LYS L CD 1 ATOM 3100 C CE . LYS B 2 142 ? -83.594 8.049 51.612 1.00 76.86 ? 142 LYS L CE 1 ATOM 3101 N NZ . LYS B 2 142 ? -82.852 7.475 52.770 1.00 77.11 ? 142 LYS L NZ 1 ATOM 3102 N N . ASP B 2 143 ? -86.135 12.868 48.995 1.00 76.60 ? 143 ASP L N 1 ATOM 3103 C CA . ASP B 2 143 ? -87.588 12.868 49.177 1.00 76.91 ? 143 ASP L CA 1 ATOM 3104 C C . ASP B 2 143 ? -88.301 12.749 47.830 1.00 77.21 ? 143 ASP L C 1 ATOM 3105 O O . ASP B 2 143 ? -88.138 13.596 46.951 1.00 77.74 ? 143 ASP L O 1 ATOM 3106 C CB . ASP B 2 143 ? -88.044 14.137 49.908 1.00 76.71 ? 143 ASP L CB 1 ATOM 3107 C CG . ASP B 2 143 ? -89.506 14.081 50.339 0.50 76.54 ? 143 ASP L CG 1 ATOM 3108 O OD1 . ASP B 2 143 ? -90.116 12.990 50.290 0.50 76.16 ? 143 ASP L OD1 1 ATOM 3109 O OD2 . ASP B 2 143 ? -90.045 15.136 50.738 0.50 76.48 ? 143 ASP L OD2 1 ATOM 3110 N N . ILE B 2 144 ? -89.078 11.683 47.675 1.00 77.02 ? 144 ILE L N 1 ATOM 3111 C CA . ILE B 2 144 ? -89.805 11.425 46.439 1.00 77.50 ? 144 ILE L CA 1 ATOM 3112 C C . ILE B 2 144 ? -90.992 10.515 46.739 1.00 78.48 ? 144 ILE L C 1 ATOM 3113 O O . ILE B 2 144 ? -90.916 9.658 47.622 1.00 79.31 ? 144 ILE L O 1 ATOM 3114 C CB . ILE B 2 144 ? -88.888 10.770 45.376 1.00 77.65 ? 144 ILE L CB 1 ATOM 3115 C CG1 . ILE B 2 144 ? -89.523 10.850 43.986 1.00 77.93 ? 144 ILE L CG1 1 ATOM 3116 C CG2 . ILE B 2 144 ? -88.575 9.318 45.741 1.00 77.74 ? 144 ILE L CG2 1 ATOM 3117 C CD1 . ILE B 2 144 ? -88.590 10.423 42.865 1.00 77.68 ? 144 ILE L CD1 1 ATOM 3118 N N . ASN B 2 145 ? -92.090 10.712 46.014 1.00 78.61 ? 145 ASN L N 1 ATOM 3119 C CA . ASN B 2 145 ? -93.299 9.932 46.237 1.00 77.97 ? 145 ASN L CA 1 ATOM 3120 C C . ASN B 2 145 ? -93.830 9.324 44.944 1.00 77.69 ? 145 ASN L C 1 ATOM 3121 O O . ASN B 2 145 ? -94.252 10.043 44.035 1.00 77.48 ? 145 ASN L O 1 ATOM 3122 C CB . ASN B 2 145 ? -94.376 10.798 46.894 1.00 78.86 ? 145 ASN L CB 1 ATOM 3123 C CG . ASN B 2 145 ? -95.540 9.981 47.429 1.00 79.70 ? 145 ASN L CG 1 ATOM 3124 O OD1 . ASN B 2 145 ? -95.371 8.831 47.844 1.00 80.66 ? 145 ASN L OD1 1 ATOM 3125 N ND2 . ASN B 2 145 ? -96.730 10.575 47.428 1.00 79.81 ? 145 ASN L ND2 1 ATOM 3126 N N . VAL B 2 146 ? -93.795 7.994 44.872 1.00 77.54 ? 146 VAL L N 1 ATOM 3127 C CA . VAL B 2 146 ? -94.346 7.251 43.743 1.00 77.38 ? 146 VAL L CA 1 ATOM 3128 C C . VAL B 2 146 ? -95.786 6.848 44.050 1.00 77.00 ? 146 VAL L C 1 ATOM 3129 O O . VAL B 2 146 ? -96.081 6.349 45.137 1.00 77.01 ? 146 VAL L O 1 ATOM 3130 C CB . VAL B 2 146 ? -93.521 5.979 43.451 1.00 77.71 ? 146 VAL L CB 1 ATOM 3131 C CG1 . VAL B 2 146 ? -94.144 5.177 42.309 1.00 77.58 ? 146 VAL L CG1 1 ATOM 3132 C CG2 . VAL B 2 146 ? -92.077 6.344 43.129 1.00 77.96 ? 146 VAL L CG2 1 ATOM 3133 N N . LYS B 2 147 ? -96.674 7.072 43.086 1.00 76.72 ? 147 LYS L N 1 ATOM 3134 C CA . LYS B 2 147 ? -98.089 6.755 43.236 1.00 76.77 ? 147 LYS L CA 1 ATOM 3135 C C . LYS B 2 147 ? -98.497 5.760 42.154 1.00 76.43 ? 147 LYS L C 1 ATOM 3136 O O . LYS B 2 147 ? -98.434 6.073 40.966 1.00 76.56 ? 147 LYS L O 1 ATOM 3137 C CB . LYS B 2 147 ? -98.923 8.035 43.126 1.00 76.96 ? 147 LYS L CB 1 ATOM 3138 C CG . LYS B 2 147 ? -100.389 7.885 43.506 1.00 76.74 ? 147 LYS L CG 1 ATOM 3139 C CD . LYS B 2 147 ? -101.118 9.215 43.377 1.00 76.71 ? 147 LYS L CD 1 ATOM 3140 C CE . LYS B 2 147 ? -102.516 9.151 43.965 1.00 76.85 ? 147 LYS L CE 1 ATOM 3141 N NZ . LYS B 2 147 ? -103.283 10.403 43.715 1.00 76.76 ? 147 LYS L NZ 1 ATOM 3142 N N . TRP B 2 148 ? -98.900 4.562 42.571 1.00 76.30 ? 148 TRP L N 1 ATOM 3143 C CA . TRP B 2 148 ? -99.339 3.524 41.635 1.00 76.58 ? 148 TRP L CA 1 ATOM 3144 C C . TRP B 2 148 ? -100.810 3.704 41.268 1.00 76.36 ? 148 TRP L C 1 ATOM 3145 O O . TRP B 2 148 ? -101.649 3.931 42.140 1.00 76.08 ? 148 TRP L O 1 ATOM 3146 C CB . TRP B 2 148 ? -99.125 2.129 42.230 1.00 76.71 ? 148 TRP L CB 1 ATOM 3147 C CG . TRP B 2 148 ? -97.734 1.618 42.062 1.00 76.77 ? 148 TRP L CG 1 ATOM 3148 C CD1 . TRP B 2 148 ? -96.779 1.504 43.027 1.00 76.72 ? 148 TRP L CD1 1 ATOM 3149 C CD2 . TRP B 2 148 ? -97.136 1.148 40.848 1.00 76.69 ? 148 TRP L CD2 1 ATOM 3150 N NE1 . TRP B 2 148 ? -95.625 0.990 42.492 1.00 76.66 ? 148 TRP L NE1 1 ATOM 3151 C CE2 . TRP B 2 148 ? -95.816 0.763 41.155 1.00 76.31 ? 148 TRP L CE2 1 ATOM 3152 C CE3 . TRP B 2 148 ? -97.590 1.015 39.530 1.00 76.82 ? 148 TRP L CE3 1 ATOM 3153 C CZ2 . TRP B 2 148 ? -94.943 0.254 40.195 1.00 76.55 ? 148 TRP L CZ2 1 ATOM 3154 C CZ3 . TRP B 2 148 ? -96.721 0.508 38.574 1.00 76.75 ? 148 TRP L CZ3 1 ATOM 3155 C CH2 . TRP B 2 148 ? -95.413 0.134 38.913 1.00 76.79 ? 148 TRP L CH2 1 ATOM 3156 N N . LYS B 2 149 ? -101.111 3.596 39.974 1.00 76.42 ? 149 LYS L N 1 ATOM 3157 C CA . LYS B 2 149 ? -102.481 3.728 39.481 1.00 76.75 ? 149 LYS L CA 1 ATOM 3158 C C . LYS B 2 149 ? -102.829 2.610 38.499 1.00 77.08 ? 149 LYS L C 1 ATOM 3159 O O . LYS B 2 149 ? -102.215 2.495 37.437 1.00 77.21 ? 149 LYS L O 1 ATOM 3160 C CB . LYS B 2 149 ? -102.682 5.090 38.811 1.00 76.39 ? 149 LYS L CB 1 ATOM 3161 C CG . LYS B 2 149 ? -102.880 6.238 39.789 1.00 76.16 ? 149 LYS L CG 1 ATOM 3162 C CD . LYS B 2 149 ? -103.440 7.469 39.094 1.00 76.42 ? 149 LYS L CD 1 ATOM 3163 C CE . LYS B 2 149 ? -103.806 8.556 40.092 1.00 76.36 ? 149 LYS L CE 1 ATOM 3164 N NZ . LYS B 2 149 ? -104.569 9.665 39.457 1.00 76.14 ? 149 LYS L NZ 1 ATOM 3165 N N . ILE B 2 150 ? -103.815 1.793 38.869 1.00 77.27 ? 150 ILE L N 1 ATOM 3166 C CA . ILE B 2 150 ? -104.310 0.714 38.015 1.00 77.41 ? 150 ILE L CA 1 ATOM 3167 C C . ILE B 2 150 ? -105.662 1.113 37.425 1.00 77.53 ? 150 ILE L C 1 ATOM 3168 O O . ILE B 2 150 ? -106.671 1.140 38.134 1.00 77.20 ? 150 ILE L O 1 ATOM 3169 C CB . ILE B 2 150 ? -104.473 -0.605 38.802 1.00 77.32 ? 150 ILE L CB 1 ATOM 3170 C CG1 . ILE B 2 150 ? -103.168 -0.974 39.514 1.00 77.33 ? 150 ILE L CG1 1 ATOM 3171 C CG2 . ILE B 2 150 ? -104.900 -1.731 37.870 1.00 77.26 ? 150 ILE L CG2 1 ATOM 3172 C CD1 . ILE B 2 150 ? -103.243 -2.273 40.288 1.00 77.23 ? 150 ILE L CD1 1 ATOM 3173 N N . ASP B 2 151 ? -105.669 1.428 36.130 1.00 77.94 ? 151 ASP L N 1 ATOM 3174 C CA . ASP B 2 151 ? -106.871 1.900 35.428 1.00 78.33 ? 151 ASP L CA 1 ATOM 3175 C C . ASP B 2 151 ? -107.499 3.125 36.106 1.00 78.55 ? 151 ASP L C 1 ATOM 3176 O O . ASP B 2 151 ? -108.722 3.218 36.226 1.00 78.58 ? 151 ASP L O 1 ATOM 3177 C CB . ASP B 2 151 ? -107.906 0.771 35.293 1.00 78.16 ? 151 ASP L CB 1 ATOM 3178 C CG . ASP B 2 151 ? -107.384 -0.414 34.498 1.00 78.10 ? 151 ASP L CG 1 ATOM 3179 O OD1 . ASP B 2 151 ? -106.160 -0.491 34.260 1.00 77.97 ? 151 ASP L OD1 1 ATOM 3180 O OD2 . ASP B 2 151 ? -108.204 -1.273 34.109 1.00 78.05 ? 151 ASP L OD2 1 ATOM 3181 N N . GLY B 2 152 ? -106.654 4.056 36.547 1.00 78.95 ? 152 GLY L N 1 ATOM 3182 C CA . GLY B 2 152 ? -107.116 5.305 37.159 1.00 79.48 ? 152 GLY L CA 1 ATOM 3183 C C . GLY B 2 152 ? -107.130 5.285 38.679 1.00 79.92 ? 152 GLY L C 1 ATOM 3184 O O . GLY B 2 152 ? -106.753 6.268 39.319 1.00 80.02 ? 152 GLY L O 1 ATOM 3185 N N . SER B 2 153 ? -107.571 4.169 39.257 1.00 80.26 ? 153 SER L N 1 ATOM 3186 C CA . SER B 2 153 ? -107.678 4.036 40.711 1.00 80.72 ? 153 SER L CA 1 ATOM 3187 C C . SER B 2 153 ? -106.310 3.862 41.364 1.00 81.23 ? 153 SER L C 1 ATOM 3188 O O . SER B 2 153 ? -105.449 3.155 40.838 1.00 81.22 ? 153 SER L O 1 ATOM 3189 C CB . SER B 2 153 ? -108.568 2.843 41.072 1.00 80.95 ? 153 SER L CB 1 ATOM 3190 O OG . SER B 2 153 ? -108.615 2.645 42.476 1.00 81.03 ? 153 SER L OG 1 ATOM 3191 N N . GLU B 2 154 ? -106.125 4.502 42.517 1.00 81.50 ? 154 GLU L N 1 ATOM 3192 C CA . GLU B 2 154 ? -104.899 4.357 43.299 1.00 81.62 ? 154 GLU L CA 1 ATOM 3193 C C . GLU B 2 154 ? -104.849 2.977 43.953 1.00 81.95 ? 154 GLU L C 1 ATOM 3194 O O . GLU B 2 154 ? -105.890 2.386 44.253 1.00 81.83 ? 154 GLU L O 1 ATOM 3195 C CB . GLU B 2 154 ? -104.823 5.445 44.376 1.00 81.56 ? 154 GLU L CB 1 ATOM 3196 C CG . GLU B 2 154 ? -103.488 5.505 45.120 1.00 81.61 ? 154 GLU L CG 1 ATOM 3197 C CD . GLU B 2 154 ? -103.438 6.609 46.164 1.00 81.91 ? 154 GLU L CD 1 ATOM 3198 O OE1 . GLU B 2 154 ? -102.326 6.925 46.638 1.00 82.10 ? 154 GLU L OE1 1 ATOM 3199 O OE2 . GLU B 2 154 ? -104.503 7.160 46.515 1.00 82.13 ? 154 GLU L OE2 1 ATOM 3200 N N . ARG B 2 155 ? -103.637 2.469 44.166 1.00 82.24 ? 155 ARG L N 1 ATOM 3201 C CA . ARG B 2 155 ? -103.440 1.199 44.859 1.00 82.12 ? 155 ARG L CA 1 ATOM 3202 C C . ARG B 2 155 ? -102.702 1.427 46.179 1.00 82.41 ? 155 ARG L C 1 ATOM 3203 O O . ARG B 2 155 ? -101.533 1.820 46.191 1.00 82.61 ? 155 ARG L O 1 ATOM 3204 C CB . ARG B 2 155 ? -102.669 0.217 43.973 1.00 82.52 ? 155 ARG L CB 1 ATOM 3205 C CG . ARG B 2 155 ? -102.696 -1.237 44.455 1.00 82.96 ? 155 ARG L CG 1 ATOM 3206 C CD . ARG B 2 155 ? -104.121 -1.798 44.524 1.00 83.36 ? 155 ARG L CD 1 ATOM 3207 N NE . ARG B 2 155 ? -104.775 -1.513 45.803 1.00 83.43 ? 155 ARG L NE 1 ATOM 3208 C CZ . ARG B 2 155 ? -106.058 -1.755 46.071 1.00 83.41 ? 155 ARG L CZ 1 ATOM 3209 N NH1 . ARG B 2 155 ? -106.858 -2.298 45.154 1.00 83.40 ? 155 ARG L NH1 1 ATOM 3210 N NH2 . ARG B 2 155 ? -106.548 -1.452 47.269 1.00 83.56 ? 155 ARG L NH2 1 ATOM 3211 N N . GLN B 2 156 ? -103.399 1.177 47.286 1.00 82.40 ? 156 GLN L N 1 ATOM 3212 C CA . GLN B 2 156 ? -102.864 1.417 48.625 1.00 82.12 ? 156 GLN L CA 1 ATOM 3213 C C . GLN B 2 156 ? -101.886 0.316 49.048 1.00 82.04 ? 156 GLN L C 1 ATOM 3214 O O . GLN B 2 156 ? -100.704 0.582 49.276 1.00 82.31 ? 156 GLN L O 1 ATOM 3215 C CB . GLN B 2 156 ? -104.017 1.518 49.633 1.00 82.39 ? 156 GLN L CB 1 ATOM 3216 C CG . GLN B 2 156 ? -103.622 2.030 51.016 1.00 82.38 ? 156 GLN L CG 1 ATOM 3217 C CD . GLN B 2 156 ? -104.796 2.070 51.985 1.00 82.35 ? 156 GLN L CD 1 ATOM 3218 O OE1 . GLN B 2 156 ? -105.762 1.316 51.848 1.00 82.14 ? 156 GLN L OE1 1 ATOM 3219 N NE2 . GLN B 2 156 ? -104.712 2.951 52.975 1.00 82.68 ? 156 GLN L NE2 1 ATOM 3220 N N . ASN B 2 157 ? -102.384 -0.917 49.135 1.00 81.55 ? 157 ASN L N 1 ATOM 3221 C CA . ASN B 2 157 ? -101.614 -2.036 49.684 1.00 81.27 ? 157 ASN L CA 1 ATOM 3222 C C . ASN B 2 157 ? -100.772 -2.762 48.635 1.00 80.72 ? 157 ASN L C 1 ATOM 3223 O O . ASN B 2 157 ? -100.950 -2.565 47.431 1.00 80.46 ? 157 ASN L O 1 ATOM 3224 C CB . ASN B 2 157 ? -102.554 -3.040 50.360 1.00 81.80 ? 157 ASN L CB 1 ATOM 3225 C CG . ASN B 2 157 ? -103.377 -2.416 51.477 1.00 82.05 ? 157 ASN L CG 1 ATOM 3226 O OD1 . ASN B 2 157 ? -103.339 -1.204 51.693 1.00 82.09 ? 157 ASN L OD1 1 ATOM 3227 N ND2 . ASN B 2 157 ? -104.129 -3.247 52.190 1.00 81.89 ? 157 ASN L ND2 1 ATOM 3228 N N . GLY B 2 158 ? -99.855 -3.603 49.110 1.00 80.59 ? 158 GLY L N 1 ATOM 3229 C CA . GLY B 2 158 ? -99.030 -4.443 48.241 1.00 80.51 ? 158 GLY L CA 1 ATOM 3230 C C . GLY B 2 158 ? -97.884 -3.714 47.557 1.00 80.18 ? 158 GLY L C 1 ATOM 3231 O O . GLY B 2 158 ? -97.421 -4.142 46.497 1.00 79.55 ? 158 GLY L O 1 ATOM 3232 N N . VAL B 2 159 ? -97.417 -2.626 48.171 1.00 80.37 ? 159 VAL L N 1 ATOM 3233 C CA . VAL B 2 159 ? -96.344 -1.807 47.603 1.00 80.08 ? 159 VAL L CA 1 ATOM 3234 C C . VAL B 2 159 ? -95.104 -1.830 48.502 1.00 80.08 ? 159 VAL L C 1 ATOM 3235 O O . VAL B 2 159 ? -95.195 -1.575 49.705 1.00 79.89 ? 159 VAL L O 1 ATOM 3236 C CB . VAL B 2 159 ? -96.800 -0.346 47.406 1.00 79.67 ? 159 VAL L CB 1 ATOM 3237 C CG1 . VAL B 2 159 ? -95.679 0.488 46.799 1.00 79.47 ? 159 VAL L CG1 1 ATOM 3238 C CG2 . VAL B 2 159 ? -98.044 -0.293 46.529 1.00 79.44 ? 159 VAL L CG2 1 ATOM 3239 N N . LEU B 2 160 ? -93.953 -2.145 47.906 1.00 80.02 ? 160 LEU L N 1 ATOM 3240 C CA . LEU B 2 160 ? -92.676 -2.177 48.620 1.00 79.58 ? 160 LEU L CA 1 ATOM 3241 C C . LEU B 2 160 ? -91.653 -1.319 47.888 1.00 79.18 ? 160 LEU L C 1 ATOM 3242 O O . LEU B 2 160 ? -91.422 -1.505 46.692 1.00 79.19 ? 160 LEU L O 1 ATOM 3243 C CB . LEU B 2 160 ? -92.158 -3.612 48.732 1.00 80.14 ? 160 LEU L CB 1 ATOM 3244 C CG . LEU B 2 160 ? -93.029 -4.586 49.529 1.00 81.17 ? 160 LEU L CG 1 ATOM 3245 C CD1 . LEU B 2 160 ? -92.494 -6.006 49.396 1.00 81.84 ? 160 LEU L CD1 1 ATOM 3246 C CD2 . LEU B 2 160 ? -93.112 -4.177 50.996 1.00 81.22 ? 160 LEU L CD2 1 ATOM 3247 N N . ASN B 2 161 ? -91.043 -0.387 48.614 1.00 78.98 ? 161 ASN L N 1 ATOM 3248 C CA . ASN B 2 161 ? -90.084 0.552 48.039 1.00 78.88 ? 161 ASN L CA 1 ATOM 3249 C C . ASN B 2 161 ? -88.698 0.371 48.639 1.00 78.73 ? 161 ASN L C 1 ATOM 3250 O O . ASN B 2 161 ? -88.556 -0.155 49.744 1.00 78.81 ? 161 ASN L O 1 ATOM 3251 C CB . ASN B 2 161 ? -90.556 1.982 48.278 1.00 78.29 ? 161 ASN L CB 1 ATOM 3252 C CG . ASN B 2 161 ? -91.956 2.225 47.757 1.00 77.40 ? 161 ASN L CG 1 ATOM 3253 O OD1 . ASN B 2 161 ? -92.271 1.896 46.615 1.00 76.65 ? 161 ASN L OD1 1 ATOM 3254 N ND2 . ASN B 2 161 ? -92.806 2.805 48.594 1.00 77.57 ? 161 ASN L ND2 1 ATOM 3255 N N . SER B 2 162 ? -87.679 0.810 47.904 1.00 78.66 ? 162 SER L N 1 ATOM 3256 C CA . SER B 2 162 ? -86.300 0.737 48.380 1.00 78.91 ? 162 SER L CA 1 ATOM 3257 C C . SER B 2 162 ? -85.423 1.787 47.705 1.00 79.26 ? 162 SER L C 1 ATOM 3258 O O . SER B 2 162 ? -85.251 1.770 46.485 1.00 79.68 ? 162 SER L O 1 ATOM 3259 C CB . SER B 2 162 ? -85.722 -0.654 48.127 1.00 78.75 ? 162 SER L CB 1 ATOM 3260 O OG . SER B 2 162 ? -84.426 -0.769 48.685 1.00 79.07 ? 162 SER L OG 1 ATOM 3261 N N . TRP B 2 163 ? -84.877 2.696 48.508 1.00 79.25 ? 163 TRP L N 1 ATOM 3262 C CA . TRP B 2 163 ? -83.945 3.710 48.023 1.00 79.42 ? 163 TRP L CA 1 ATOM 3263 C C . TRP B 2 163 ? -82.531 3.148 48.024 1.00 78.98 ? 163 TRP L C 1 ATOM 3264 O O . TRP B 2 163 ? -82.176 2.349 48.891 1.00 79.02 ? 163 TRP L O 1 ATOM 3265 C CB . TRP B 2 163 ? -83.982 4.956 48.916 1.00 81.28 ? 163 TRP L CB 1 ATOM 3266 C CG . TRP B 2 163 ? -85.135 5.879 48.659 1.00 81.52 ? 163 TRP L CG 1 ATOM 3267 C CD1 . TRP B 2 163 ? -85.106 7.044 47.949 1.00 81.56 ? 163 TRP L CD1 1 ATOM 3268 C CD2 . TRP B 2 163 ? -86.481 5.727 49.127 1.00 81.57 ? 163 TRP L CD2 1 ATOM 3269 N NE1 . TRP B 2 163 ? -86.351 7.625 47.940 1.00 81.69 ? 163 TRP L NE1 1 ATOM 3270 C CE2 . TRP B 2 163 ? -87.214 6.838 48.656 1.00 81.90 ? 163 TRP L CE2 1 ATOM 3271 C CE3 . TRP B 2 163 ? -87.139 4.760 49.897 1.00 81.49 ? 163 TRP L CE3 1 ATOM 3272 C CZ2 . TRP B 2 163 ? -88.574 7.007 48.927 1.00 81.75 ? 163 TRP L CZ2 1 ATOM 3273 C CZ3 . TRP B 2 163 ? -88.490 4.929 50.166 1.00 81.56 ? 163 TRP L CZ3 1 ATOM 3274 C CH2 . TRP B 2 163 ? -89.193 6.044 49.681 1.00 81.61 ? 163 TRP L CH2 1 ATOM 3275 N N . THR B 2 164 ? -81.721 3.572 47.059 1.00 78.74 ? 164 THR L N 1 ATOM 3276 C CA . THR B 2 164 ? -80.302 3.244 47.068 1.00 78.64 ? 164 THR L CA 1 ATOM 3277 C C . THR B 2 164 ? -79.580 4.168 48.031 1.00 78.55 ? 164 THR L C 1 ATOM 3278 O O . THR B 2 164 ? -80.141 5.159 48.506 1.00 78.10 ? 164 THR L O 1 ATOM 3279 C CB . THR B 2 164 ? -79.648 3.405 45.677 1.00 78.82 ? 164 THR L CB 1 ATOM 3280 O OG1 . THR B 2 164 ? -79.750 4.768 45.247 1.00 79.14 ? 164 THR L OG1 1 ATOM 3281 C CG2 . THR B 2 164 ? -80.308 2.497 44.658 1.00 79.23 ? 164 THR L CG2 1 ATOM 3282 N N . ASP B 2 165 ? -78.326 3.835 48.311 1.00 78.94 ? 165 ASP L N 1 ATOM 3283 C CA . ASP B 2 165 ? -77.441 4.727 49.041 1.00 78.46 ? 165 ASP L CA 1 ATOM 3284 C C . ASP B 2 165 ? -77.124 5.932 48.162 1.00 78.06 ? 165 ASP L C 1 ATOM 3285 O O . ASP B 2 165 ? -77.272 5.873 46.940 1.00 78.36 ? 165 ASP L O 1 ATOM 3286 C CB . ASP B 2 165 ? -76.152 4.000 49.428 1.00 79.16 ? 165 ASP L CB 1 ATOM 3287 C CG . ASP B 2 165 ? -76.404 2.804 50.328 0.50 79.72 ? 165 ASP L CG 1 ATOM 3288 O OD1 . ASP B 2 165 ? -76.881 3.003 51.465 0.50 79.83 ? 165 ASP L OD1 1 ATOM 3289 O OD2 . ASP B 2 165 ? -76.127 1.664 49.898 0.50 80.00 ? 165 ASP L OD2 1 ATOM 3290 N N . GLN B 2 166 ? -76.708 7.029 48.783 1.00 77.55 ? 166 GLN L N 1 ATOM 3291 C CA . GLN B 2 166 ? -76.257 8.192 48.037 1.00 77.55 ? 166 GLN L CA 1 ATOM 3292 C C . GLN B 2 166 ? -75.020 7.798 47.236 1.00 77.39 ? 166 GLN L C 1 ATOM 3293 O O . GLN B 2 166 ? -74.133 7.119 47.754 1.00 77.94 ? 166 GLN L O 1 ATOM 3294 C CB . GLN B 2 166 ? -75.945 9.350 48.985 1.00 77.42 ? 166 GLN L CB 1 ATOM 3295 C CG . GLN B 2 166 ? -75.702 10.673 48.282 1.00 77.77 ? 166 GLN L CG 1 ATOM 3296 C CD . GLN B 2 166 ? -75.739 11.859 49.228 1.00 78.24 ? 166 GLN L CD 1 ATOM 3297 O OE1 . GLN B 2 166 ? -75.383 11.746 50.403 1.00 79.01 ? 166 GLN L OE1 1 ATOM 3298 N NE2 . GLN B 2 166 ? -76.166 13.008 48.716 1.00 78.41 ? 166 GLN L NE2 1 ATOM 3299 N N . ASP B 2 167 ? -74.976 8.199 45.969 1.00 77.64 ? 167 ASP L N 1 ATOM 3300 C CA . ASP B 2 167 ? -73.904 7.781 45.069 1.00 77.54 ? 167 ASP L CA 1 ATOM 3301 C C . ASP B 2 167 ? -72.599 8.487 45.418 1.00 77.06 ? 167 ASP L C 1 ATOM 3302 O O . ASP B 2 167 ? -72.587 9.686 45.680 1.00 76.56 ? 167 ASP L O 1 ATOM 3303 C CB . ASP B 2 167 ? -74.282 8.072 43.614 1.00 78.07 ? 167 ASP L CB 1 ATOM 3304 C CG . ASP B 2 167 ? -73.291 7.483 42.614 1.00 78.60 ? 167 ASP L CG 1 ATOM 3305 O OD1 . ASP B 2 167 ? -72.988 8.160 41.608 1.00 78.72 ? 167 ASP L OD1 1 ATOM 3306 O OD2 . ASP B 2 167 ? -72.814 6.347 42.828 1.00 79.62 ? 167 ASP L OD2 1 ATOM 3307 N N . SER B 2 168 ? -71.505 7.733 45.414 1.00 77.49 ? 168 SER L N 1 ATOM 3308 C CA . SER B 2 168 ? -70.194 8.260 45.789 1.00 77.88 ? 168 SER L CA 1 ATOM 3309 C C . SER B 2 168 ? -69.707 9.355 44.838 1.00 78.20 ? 168 SER L C 1 ATOM 3310 O O . SER B 2 168 ? -69.058 10.309 45.267 1.00 78.15 ? 168 SER L O 1 ATOM 3311 C CB . SER B 2 168 ? -69.166 7.126 45.840 1.00 77.99 ? 168 SER L CB 1 ATOM 3312 O OG . SER B 2 168 ? -69.206 6.346 44.656 1.00 78.07 ? 168 SER L OG 1 ATOM 3313 N N . LYS B 2 169 ? -70.032 9.216 43.554 1.00 78.57 ? 169 LYS L N 1 ATOM 3314 C CA . LYS B 2 169 ? -69.526 10.122 42.522 1.00 78.62 ? 169 LYS L CA 1 ATOM 3315 C C . LYS B 2 169 ? -70.424 11.347 42.322 1.00 78.21 ? 169 LYS L C 1 ATOM 3316 O O . LYS B 2 169 ? -69.958 12.482 42.445 1.00 78.03 ? 169 LYS L O 1 ATOM 3317 C CB . LYS B 2 169 ? -69.342 9.368 41.201 1.00 78.94 ? 169 LYS L CB 1 ATOM 3318 C CG . LYS B 2 169 ? -68.205 8.347 41.240 1.00 79.41 ? 169 LYS L CG 1 ATOM 3319 C CD . LYS B 2 169 ? -68.379 7.236 40.204 1.00 79.50 ? 169 LYS L CD 1 ATOM 3320 C CE . LYS B 2 169 ? -68.210 7.749 38.781 1.00 79.85 ? 169 LYS L CE 1 ATOM 3321 N NZ . LYS B 2 169 ? -68.214 6.639 37.784 1.00 79.76 ? 169 LYS L NZ 1 ATOM 3322 N N . ASP B 2 170 ? -71.704 11.120 42.022 1.00 78.14 ? 170 ASP L N 1 ATOM 3323 C CA . ASP B 2 170 ? -72.633 12.222 41.709 1.00 78.69 ? 170 ASP L CA 1 ATOM 3324 C C . ASP B 2 170 ? -73.610 12.577 42.846 1.00 78.36 ? 170 ASP L C 1 ATOM 3325 O O . ASP B 2 170 ? -74.385 13.522 42.716 1.00 77.92 ? 170 ASP L O 1 ATOM 3326 C CB . ASP B 2 170 ? -73.402 11.938 40.404 1.00 79.97 ? 170 ASP L CB 1 ATOM 3327 C CG . ASP B 2 170 ? -74.343 10.744 40.510 1.00 81.05 ? 170 ASP L CG 1 ATOM 3328 O OD1 . ASP B 2 170 ? -74.862 10.474 41.610 1.00 82.00 ? 170 ASP L OD1 1 ATOM 3329 O OD2 . ASP B 2 170 ? -74.573 10.077 39.481 1.00 81.09 ? 170 ASP L OD2 1 ATOM 3330 N N . SER B 2 171 ? -73.578 11.816 43.941 1.00 78.28 ? 171 SER L N 1 ATOM 3331 C CA . SER B 2 171 ? -74.376 12.119 45.139 1.00 78.21 ? 171 SER L CA 1 ATOM 3332 C C . SER B 2 171 ? -75.895 12.093 44.903 1.00 78.23 ? 171 SER L C 1 ATOM 3333 O O . SER B 2 171 ? -76.656 12.675 45.682 1.00 77.88 ? 171 SER L O 1 ATOM 3334 C CB . SER B 2 171 ? -73.966 13.476 45.730 1.00 77.92 ? 171 SER L CB 1 ATOM 3335 O OG . SER B 2 171 ? -72.556 13.625 45.757 1.00 77.33 ? 171 SER L OG 1 ATOM 3336 N N . THR B 2 172 ? -76.330 11.410 43.844 1.00 78.20 ? 172 THR L N 1 ATOM 3337 C CA . THR B 2 172 ? -77.753 11.282 43.541 1.00 78.26 ? 172 THR L CA 1 ATOM 3338 C C . THR B 2 172 ? -78.314 10.032 44.200 1.00 78.26 ? 172 THR L C 1 ATOM 3339 O O . THR B 2 172 ? -77.564 9.151 44.627 1.00 77.60 ? 172 THR L O 1 ATOM 3340 C CB . THR B 2 172 ? -78.020 11.184 42.023 1.00 78.59 ? 172 THR L CB 1 ATOM 3341 O OG1 . THR B 2 172 ? -77.466 9.965 41.510 1.00 79.36 ? 172 THR L OG1 1 ATOM 3342 C CG2 . THR B 2 172 ? -77.418 12.362 41.286 1.00 78.20 ? 172 THR L CG2 1 ATOM 3343 N N . TYR B 2 173 ? -79.640 9.965 44.272 1.00 78.41 ? 173 TYR L N 1 ATOM 3344 C CA . TYR B 2 173 ? -80.337 8.800 44.801 1.00 78.32 ? 173 TYR L CA 1 ATOM 3345 C C . TYR B 2 173 ? -81.078 8.085 43.685 1.00 78.93 ? 173 TYR L C 1 ATOM 3346 O O . TYR B 2 173 ? -81.291 8.643 42.607 1.00 79.41 ? 173 TYR L O 1 ATOM 3347 C CB . TYR B 2 173 ? -81.334 9.221 45.878 1.00 77.80 ? 173 TYR L CB 1 ATOM 3348 C CG . TYR B 2 173 ? -80.690 9.790 47.117 1.00 77.88 ? 173 TYR L CG 1 ATOM 3349 C CD1 . TYR B 2 173 ? -80.358 8.968 48.190 1.00 77.92 ? 173 TYR L CD1 1 ATOM 3350 C CD2 . TYR B 2 173 ? -80.413 11.150 47.221 1.00 77.84 ? 173 TYR L CD2 1 ATOM 3351 C CE1 . TYR B 2 173 ? -79.769 9.484 49.331 1.00 77.92 ? 173 TYR L CE1 1 ATOM 3352 C CE2 . TYR B 2 173 ? -79.821 11.678 48.360 1.00 77.79 ? 173 TYR L CE2 1 ATOM 3353 C CZ . TYR B 2 173 ? -79.502 10.841 49.413 1.00 77.82 ? 173 TYR L CZ 1 ATOM 3354 O OH . TYR B 2 173 ? -78.917 11.359 50.545 1.00 77.93 ? 173 TYR L OH 1 ATOM 3355 N N . SER B 2 174 ? -81.460 6.842 43.950 1.00 78.73 ? 174 SER L N 1 ATOM 3356 C CA . SER B 2 174 ? -82.313 6.085 43.044 1.00 78.47 ? 174 SER L CA 1 ATOM 3357 C C . SER B 2 174 ? -83.275 5.232 43.855 1.00 78.48 ? 174 SER L C 1 ATOM 3358 O O . SER B 2 174 ? -82.962 4.827 44.976 1.00 78.15 ? 174 SER L O 1 ATOM 3359 C CB . SER B 2 174 ? -81.473 5.210 42.118 1.00 78.19 ? 174 SER L CB 1 ATOM 3360 O OG . SER B 2 174 ? -80.631 6.005 41.303 1.00 78.16 ? 174 SER L OG 1 ATOM 3361 N N . MET B 2 175 ? -84.449 4.970 43.288 1.00 78.64 ? 175 MET L N 1 ATOM 3362 C CA . MET B 2 175 ? -85.478 4.195 43.970 1.00 78.63 ? 175 MET L CA 1 ATOM 3363 C C . MET B 2 175 ? -86.092 3.162 43.039 1.00 78.11 ? 175 MET L C 1 ATOM 3364 O O . MET B 2 175 ? -86.296 3.429 41.857 1.00 78.75 ? 175 MET L O 1 ATOM 3365 C CB . MET B 2 175 ? -86.573 5.126 44.494 1.00 79.32 ? 175 MET L CB 1 ATOM 3366 C CG . MET B 2 175 ? -87.836 4.410 44.947 1.00 79.44 ? 175 MET L CG 1 ATOM 3367 S SD . MET B 2 175 ? -88.921 5.465 45.913 1.00 80.34 ? 175 MET L SD 1 ATOM 3368 C CE . MET B 2 175 ? -90.443 4.520 45.863 1.00 80.13 ? 175 MET L CE 1 ATOM 3369 N N . SER B 2 176 ? -86.373 1.980 43.580 1.00 77.21 ? 176 SER L N 1 ATOM 3370 C CA . SER B 2 176 ? -87.228 1.013 42.905 1.00 77.20 ? 176 SER L CA 1 ATOM 3371 C C . SER B 2 176 ? -88.566 0.975 43.627 1.00 76.89 ? 176 SER L C 1 ATOM 3372 O O . SER B 2 176 ? -88.637 1.224 44.833 1.00 77.07 ? 176 SER L O 1 ATOM 3373 C CB . SER B 2 176 ? -86.590 -0.379 42.890 1.00 76.97 ? 176 SER L CB 1 ATOM 3374 O OG . SER B 2 176 ? -86.829 -1.076 44.100 1.00 76.99 ? 176 SER L OG 1 ATOM 3375 N N . SER B 2 177 ? -89.625 0.678 42.881 1.00 76.60 ? 177 SER L N 1 ATOM 3376 C CA . SER B 2 177 ? -90.958 0.542 43.449 1.00 76.10 ? 177 SER L CA 1 ATOM 3377 C C . SER B 2 177 ? -91.632 -0.683 42.853 1.00 75.61 ? 177 SER L C 1 ATOM 3378 O O . SER B 2 177 ? -91.700 -0.819 41.633 1.00 75.55 ? 177 SER L O 1 ATOM 3379 C CB . SER B 2 177 ? -91.786 1.788 43.159 1.00 75.80 ? 177 SER L CB 1 ATOM 3380 O OG . SER B 2 177 ? -92.990 1.771 43.900 1.00 75.67 ? 177 SER L OG 1 ATOM 3381 N N . THR B 2 178 ? -92.123 -1.569 43.719 1.00 75.64 ? 178 THR L N 1 ATOM 3382 C CA . THR B 2 178 ? -92.737 -2.824 43.288 1.00 75.51 ? 178 THR L CA 1 ATOM 3383 C C . THR B 2 178 ? -94.175 -2.940 43.784 1.00 74.78 ? 178 THR L C 1 ATOM 3384 O O . THR B 2 178 ? -94.418 -2.988 44.990 1.00 74.27 ? 178 THR L O 1 ATOM 3385 C CB . THR B 2 178 ? -91.943 -4.039 43.809 1.00 76.11 ? 178 THR L CB 1 ATOM 3386 O OG1 . THR B 2 178 ? -90.648 -4.068 43.198 1.00 76.94 ? 178 THR L OG1 1 ATOM 3387 C CG2 . THR B 2 178 ? -92.674 -5.340 43.497 1.00 75.90 ? 178 THR L CG2 1 ATOM 3388 N N . LEU B 2 179 ? -95.118 -2.983 42.845 1.00 74.68 ? 179 LEU L N 1 ATOM 3389 C CA . LEU B 2 179 ? -96.509 -3.308 43.148 1.00 74.82 ? 179 LEU L CA 1 ATOM 3390 C C . LEU B 2 179 ? -96.736 -4.786 42.841 1.00 73.76 ? 179 LEU L C 1 ATOM 3391 O O . LEU B 2 179 ? -96.482 -5.232 41.724 1.00 72.60 ? 179 LEU L O 1 ATOM 3392 C CB . LEU B 2 179 ? -97.459 -2.435 42.320 1.00 74.97 ? 179 LEU L CB 1 ATOM 3393 C CG . LEU B 2 179 ? -98.958 -2.752 42.394 1.00 74.91 ? 179 LEU L CG 1 ATOM 3394 C CD1 . LEU B 2 179 ? -99.438 -2.858 43.836 1.00 75.10 ? 179 LEU L CD1 1 ATOM 3395 C CD2 . LEU B 2 179 ? -99.754 -1.702 41.640 1.00 74.85 ? 179 LEU L CD2 1 ATOM 3396 N N . THR B 2 180 ? -97.206 -5.538 43.836 1.00 74.31 ? 180 THR L N 1 ATOM 3397 C CA . THR B 2 180 ? -97.355 -6.989 43.712 1.00 74.96 ? 180 THR L CA 1 ATOM 3398 C C . THR B 2 180 ? -98.815 -7.419 43.851 1.00 75.21 ? 180 THR L C 1 ATOM 3399 O O . THR B 2 180 ? -99.373 -7.414 44.950 1.00 75.54 ? 180 THR L O 1 ATOM 3400 C CB . THR B 2 180 ? -96.511 -7.727 44.769 1.00 75.27 ? 180 THR L CB 1 ATOM 3401 O OG1 . THR B 2 180 ? -95.148 -7.292 44.684 1.00 76.18 ? 180 THR L OG1 1 ATOM 3402 C CG2 . THR B 2 180 ? -96.575 -9.237 44.554 1.00 74.59 ? 180 THR L CG2 1 ATOM 3403 N N . LEU B 2 181 ? -99.421 -7.793 42.726 1.00 74.98 ? 181 LEU L N 1 ATOM 3404 C CA . LEU B 2 181 ? -100.788 -8.305 42.702 1.00 75.20 ? 181 LEU L CA 1 ATOM 3405 C C . LEU B 2 181 ? -100.789 -9.805 42.415 1.00 74.90 ? 181 LEU L C 1 ATOM 3406 O O . LEU B 2 181 ? -99.741 -10.397 42.145 1.00 74.88 ? 181 LEU L O 1 ATOM 3407 C CB . LEU B 2 181 ? -101.603 -7.581 41.628 1.00 75.14 ? 181 LEU L CB 1 ATOM 3408 C CG . LEU B 2 181 ? -101.704 -6.062 41.758 1.00 74.54 ? 181 LEU L CG 1 ATOM 3409 C CD1 . LEU B 2 181 ? -102.261 -5.467 40.478 1.00 74.51 ? 181 LEU L CD1 1 ATOM 3410 C CD2 . LEU B 2 181 ? -102.561 -5.678 42.954 1.00 74.43 ? 181 LEU L CD2 1 ATOM 3411 N N . THR B 2 182 ? -101.970 -10.411 42.478 1.00 74.59 ? 182 THR L N 1 ATOM 3412 C CA . THR B 2 182 ? -102.141 -11.808 42.090 1.00 75.28 ? 182 THR L CA 1 ATOM 3413 C C . THR B 2 182 ? -102.353 -11.906 40.580 1.00 75.51 ? 182 THR L C 1 ATOM 3414 O O . THR B 2 182 ? -102.661 -10.909 39.923 1.00 75.63 ? 182 THR L O 1 ATOM 3415 C CB . THR B 2 182 ? -103.332 -12.453 42.824 1.00 75.69 ? 182 THR L CB 1 ATOM 3416 O OG1 . THR B 2 182 ? -104.439 -11.543 42.838 1.00 75.94 ? 182 THR L OG1 1 ATOM 3417 C CG2 . THR B 2 182 ? -102.952 -12.798 44.256 1.00 75.81 ? 182 THR L CG2 1 ATOM 3418 N N . LYS B 2 183 ? -102.180 -13.108 40.035 1.00 75.65 ? 183 LYS L N 1 ATOM 3419 C CA . LYS B 2 183 ? -102.333 -13.342 38.595 1.00 75.43 ? 183 LYS L CA 1 ATOM 3420 C C . LYS B 2 183 ? -103.739 -12.985 38.114 1.00 74.98 ? 183 LYS L C 1 ATOM 3421 O O . LYS B 2 183 ? -103.902 -12.408 37.039 1.00 74.50 ? 183 LYS L O 1 ATOM 3422 C CB . LYS B 2 183 ? -102.023 -14.804 38.256 1.00 75.61 ? 183 LYS L CB 1 ATOM 3423 C CG . LYS B 2 183 ? -102.020 -15.129 36.763 1.00 75.72 ? 183 LYS L CG 1 ATOM 3424 C CD . LYS B 2 183 ? -101.888 -16.631 36.525 1.00 75.76 ? 183 LYS L CD 1 ATOM 3425 C CE . LYS B 2 183 ? -101.969 -16.976 35.046 1.00 75.72 ? 183 LYS L CE 1 ATOM 3426 N NZ . LYS B 2 183 ? -101.760 -18.429 34.800 1.00 75.69 ? 183 LYS L NZ 1 ATOM 3427 N N . ASP B 2 184 ? -104.746 -13.329 38.917 1.00 75.26 ? 184 ASP L N 1 ATOM 3428 C CA . ASP B 2 184 ? -106.149 -13.070 38.564 1.00 75.19 ? 184 ASP L CA 1 ATOM 3429 C C . ASP B 2 184 ? -106.498 -11.576 38.545 1.00 75.14 ? 184 ASP L C 1 ATOM 3430 O O . ASP B 2 184 ? -107.364 -11.147 37.779 1.00 75.23 ? 184 ASP L O 1 ATOM 3431 C CB . ASP B 2 184 ? -107.103 -13.831 39.507 1.00 75.41 ? 184 ASP L CB 1 ATOM 3432 C CG . ASP B 2 184 ? -106.972 -13.401 40.966 1.00 75.73 ? 184 ASP L CG 1 ATOM 3433 O OD1 . ASP B 2 184 ? -105.974 -12.740 41.315 1.00 76.38 ? 184 ASP L OD1 1 ATOM 3434 O OD2 . ASP B 2 184 ? -107.869 -13.736 41.767 1.00 75.35 ? 184 ASP L OD2 1 ATOM 3435 N N . GLU B 2 185 ? -105.821 -10.793 39.384 1.00 74.84 ? 185 GLU L N 1 ATOM 3436 C CA . GLU B 2 185 ? -106.080 -9.357 39.476 1.00 74.44 ? 185 GLU L CA 1 ATOM 3437 C C . GLU B 2 185 ? -105.381 -8.614 38.340 1.00 73.60 ? 185 GLU L C 1 ATOM 3438 O O . GLU B 2 185 ? -105.961 -7.713 37.736 1.00 73.55 ? 185 GLU L O 1 ATOM 3439 C CB . GLU B 2 185 ? -105.621 -8.812 40.834 1.00 75.31 ? 185 GLU L CB 1 ATOM 3440 C CG . GLU B 2 185 ? -106.528 -7.730 41.423 1.00 76.23 ? 185 GLU L CG 1 ATOM 3441 C CD . GLU B 2 185 ? -106.489 -6.420 40.657 1.00 77.14 ? 185 GLU L CD 1 ATOM 3442 O OE1 . GLU B 2 185 ? -107.548 -5.764 40.557 1.00 77.54 ? 185 GLU L OE1 1 ATOM 3443 O OE2 . GLU B 2 185 ? -105.406 -6.037 40.165 1.00 77.57 ? 185 GLU L OE2 1 ATOM 3444 N N . TYR B 2 186 ? -104.137 -8.995 38.054 1.00 73.13 ? 186 TYR L N 1 ATOM 3445 C CA . TYR B 2 186 ? -103.369 -8.367 36.975 1.00 73.50 ? 186 TYR L CA 1 ATOM 3446 C C . TYR B 2 186 ? -103.990 -8.642 35.604 1.00 73.80 ? 186 TYR L C 1 ATOM 3447 O O . TYR B 2 186 ? -104.052 -7.750 34.757 1.00 74.26 ? 186 TYR L O 1 ATOM 3448 C CB . TYR B 2 186 ? -101.910 -8.835 36.990 1.00 72.48 ? 186 TYR L CB 1 ATOM 3449 C CG . TYR B 2 186 ? -101.122 -8.388 35.776 1.00 72.45 ? 186 TYR L CG 1 ATOM 3450 C CD1 . TYR B 2 186 ? -100.691 -7.074 35.647 1.00 72.16 ? 186 TYR L CD1 1 ATOM 3451 C CD2 . TYR B 2 186 ? -100.822 -9.279 34.749 1.00 72.47 ? 186 TYR L CD2 1 ATOM 3452 C CE1 . TYR B 2 186 ? -99.976 -6.656 34.531 1.00 72.17 ? 186 TYR L CE1 1 ATOM 3453 C CE2 . TYR B 2 186 ? -100.108 -8.872 33.630 1.00 72.46 ? 186 TYR L CE2 1 ATOM 3454 C CZ . TYR B 2 186 ? -99.688 -7.561 33.527 1.00 72.20 ? 186 TYR L CZ 1 ATOM 3455 O OH . TYR B 2 186 ? -98.981 -7.158 32.419 1.00 72.23 ? 186 TYR L OH 1 ATOM 3456 N N . GLU B 2 187 ? -104.460 -9.870 35.395 1.00 73.78 ? 187 GLU L N 1 ATOM 3457 C CA . GLU B 2 187 ? -105.115 -10.246 34.139 1.00 73.83 ? 187 GLU L CA 1 ATOM 3458 C C . GLU B 2 187 ? -106.549 -9.699 34.048 1.00 73.67 ? 187 GLU L C 1 ATOM 3459 O O . GLU B 2 187 ? -107.363 -10.208 33.273 1.00 73.91 ? 187 GLU L O 1 ATOM 3460 C CB . GLU B 2 187 ? -105.125 -11.776 33.982 1.00 75.05 ? 187 GLU L CB 1 ATOM 3461 C CG . GLU B 2 187 ? -103.744 -12.404 33.778 1.00 76.02 ? 187 GLU L CG 1 ATOM 3462 C CD . GLU B 2 187 ? -103.190 -12.192 32.375 1.00 76.82 ? 187 GLU L CD 1 ATOM 3463 O OE1 . GLU B 2 187 ? -101.985 -11.888 32.252 1.00 77.15 ? 187 GLU L OE1 1 ATOM 3464 O OE2 . GLU B 2 187 ? -103.955 -12.333 31.395 1.00 77.06 ? 187 GLU L OE2 1 ATOM 3465 N N . ARG B 2 188 ? -106.849 -8.661 34.829 1.00 73.36 ? 188 ARG L N 1 ATOM 3466 C CA . ARG B 2 188 ? -108.174 -8.048 34.840 1.00 73.39 ? 188 ARG L CA 1 ATOM 3467 C C . ARG B 2 188 ? -108.107 -6.508 34.775 1.00 73.45 ? 188 ARG L C 1 ATOM 3468 O O . ARG B 2 188 ? -109.040 -5.824 35.192 1.00 73.53 ? 188 ARG L O 1 ATOM 3469 C CB . ARG B 2 188 ? -108.946 -8.515 36.084 1.00 73.01 ? 188 ARG L CB 1 ATOM 3470 C CG . ARG B 2 188 ? -110.324 -7.889 36.230 1.00 73.14 ? 188 ARG L CG 1 ATOM 3471 C CD . ARG B 2 188 ? -111.361 -8.832 36.770 1.00 73.14 ? 188 ARG L CD 1 ATOM 3472 N NE . ARG B 2 188 ? -112.693 -8.266 36.554 1.00 73.14 ? 188 ARG L NE 1 ATOM 3473 C CZ . ARG B 2 188 ? -113.785 -8.957 36.230 0.50 72.66 ? 188 ARG L CZ 1 ATOM 3474 N NH1 . ARG B 2 188 ? -113.742 -10.276 36.064 1.00 72.40 ? 188 ARG L NH1 1 ATOM 3475 N NH2 . ARG B 2 188 ? -114.935 -8.316 36.060 0.50 72.67 ? 188 ARG L NH2 1 ATOM 3476 N N . HIS B 2 189 ? -107.018 -5.965 34.233 1.00 73.43 ? 189 HIS L N 1 ATOM 3477 C CA . HIS B 2 189 ? -106.876 -4.510 34.087 1.00 73.72 ? 189 HIS L CA 1 ATOM 3478 C C . HIS B 2 189 ? -105.914 -4.152 32.953 1.00 74.43 ? 189 HIS L C 1 ATOM 3479 O O . HIS B 2 189 ? -104.857 -4.767 32.811 1.00 74.92 ? 189 HIS L O 1 ATOM 3480 C CB . HIS B 2 189 ? -106.393 -3.882 35.399 1.00 72.60 ? 189 HIS L CB 1 ATOM 3481 C CG . HIS B 2 189 ? -107.425 -3.877 36.484 1.00 71.98 ? 189 HIS L CG 1 ATOM 3482 N ND1 . HIS B 2 189 ? -108.555 -3.090 36.432 1.00 71.91 ? 189 HIS L ND1 1 ATOM 3483 C CD2 . HIS B 2 189 ? -107.499 -4.566 37.646 1.00 71.66 ? 189 HIS L CD2 1 ATOM 3484 C CE1 . HIS B 2 189 ? -109.280 -3.294 37.518 1.00 71.75 ? 189 HIS L CE1 1 ATOM 3485 N NE2 . HIS B 2 189 ? -108.661 -4.185 38.271 1.00 71.27 ? 189 HIS L NE2 1 ATOM 3486 N N . ASN B 2 190 ? -106.283 -3.148 32.158 1.00 74.59 ? 190 ASN L N 1 ATOM 3487 C CA . ASN B 2 190 ? -105.506 -2.767 30.977 1.00 74.91 ? 190 ASN L CA 1 ATOM 3488 C C . ASN B 2 190 ? -104.239 -1.983 31.319 1.00 74.96 ? 190 ASN L C 1 ATOM 3489 O O . ASN B 2 190 ? -103.128 -2.490 31.157 1.00 74.63 ? 190 ASN L O 1 ATOM 3490 C CB . ASN B 2 190 ? -106.369 -1.954 30.001 1.00 75.54 ? 190 ASN L CB 1 ATOM 3491 C CG . ASN B 2 190 ? -107.502 -2.770 29.396 1.00 76.42 ? 190 ASN L CG 1 ATOM 3492 O OD1 . ASN B 2 190 ? -107.658 -3.956 29.688 1.00 76.78 ? 190 ASN L OD1 1 ATOM 3493 N ND2 . ASN B 2 190 ? -108.300 -2.131 28.546 1.00 76.72 ? 190 ASN L ND2 1 ATOM 3494 N N . SER B 2 191 ? -104.413 -0.751 31.796 1.00 75.42 ? 191 SER L N 1 ATOM 3495 C CA . SER B 2 191 ? -103.296 0.182 31.966 1.00 75.84 ? 191 SER L CA 1 ATOM 3496 C C . SER B 2 191 ? -102.685 0.118 33.363 1.00 76.15 ? 191 SER L C 1 ATOM 3497 O O . SER B 2 191 ? -103.371 -0.176 34.343 1.00 76.28 ? 191 SER L O 1 ATOM 3498 C CB . SER B 2 191 ? -103.748 1.616 31.674 1.00 76.32 ? 191 SER L CB 1 ATOM 3499 O OG . SER B 2 191 ? -104.625 2.093 32.679 1.00 76.70 ? 191 SER L OG 1 ATOM 3500 N N . TYR B 2 192 ? -101.388 0.402 33.437 1.00 76.24 ? 192 TYR L N 1 ATOM 3501 C CA . TYR B 2 192 ? -100.668 0.465 34.704 1.00 76.35 ? 192 TYR L CA 1 ATOM 3502 C C . TYR B 2 192 ? -99.720 1.656 34.691 1.00 76.55 ? 192 TYR L C 1 ATOM 3503 O O . TYR B 2 192 ? -98.964 1.840 33.737 1.00 76.41 ? 192 TYR L O 1 ATOM 3504 C CB . TYR B 2 192 ? -99.892 -0.827 34.935 1.00 75.61 ? 192 TYR L CB 1 ATOM 3505 C CG . TYR B 2 192 ? -100.785 -2.019 35.157 1.00 75.50 ? 192 TYR L CG 1 ATOM 3506 C CD1 . TYR B 2 192 ? -101.295 -2.300 36.418 1.00 75.53 ? 192 TYR L CD1 1 ATOM 3507 C CD2 . TYR B 2 192 ? -101.134 -2.856 34.104 1.00 75.44 ? 192 TYR L CD2 1 ATOM 3508 C CE1 . TYR B 2 192 ? -102.122 -3.389 36.629 1.00 75.50 ? 192 TYR L CE1 1 ATOM 3509 C CE2 . TYR B 2 192 ? -101.962 -3.947 34.303 1.00 75.44 ? 192 TYR L CE2 1 ATOM 3510 C CZ . TYR B 2 192 ? -102.453 -4.207 35.568 1.00 75.45 ? 192 TYR L CZ 1 ATOM 3511 O OH . TYR B 2 192 ? -103.271 -5.288 35.774 1.00 75.54 ? 192 TYR L OH 1 ATOM 3512 N N . THR B 2 193 ? -99.766 2.461 35.751 1.00 76.97 ? 193 THR L N 1 ATOM 3513 C CA . THR B 2 193 ? -98.993 3.696 35.815 1.00 77.68 ? 193 THR L CA 1 ATOM 3514 C C . THR B 2 193 ? -98.353 3.902 37.185 1.00 78.54 ? 193 THR L C 1 ATOM 3515 O O . THR B 2 193 ? -98.985 3.665 38.216 1.00 78.53 ? 193 THR L O 1 ATOM 3516 C CB . THR B 2 193 ? -99.882 4.916 35.514 1.00 77.41 ? 193 THR L CB 1 ATOM 3517 O OG1 . THR B 2 193 ? -100.509 4.751 34.237 1.00 77.69 ? 193 THR L OG1 1 ATOM 3518 C CG2 . THR B 2 193 ? -99.058 6.195 35.509 1.00 77.17 ? 193 THR L CG2 1 ATOM 3519 N N . CYS B 2 194 ? -97.092 4.331 37.178 1.00 78.95 ? 194 CYS L N 1 ATOM 3520 C CA . CYS B 2 194 ? -96.438 4.861 38.369 1.00 79.27 ? 194 CYS L CA 1 ATOM 3521 C C . CYS B 2 194 ? -96.027 6.307 38.099 1.00 79.69 ? 194 CYS L C 1 ATOM 3522 O O . CYS B 2 194 ? -95.011 6.560 37.451 1.00 80.32 ? 194 CYS L O 1 ATOM 3523 C CB . CYS B 2 194 ? -95.219 4.012 38.763 1.00 81.02 ? 194 CYS L CB 1 ATOM 3524 S SG . CYS B 2 194 ? -93.999 3.728 37.443 1.00 82.11 ? 194 CYS L SG 1 ATOM 3525 N N . GLU B 2 195 ? -96.843 7.250 38.564 1.00 79.35 ? 195 GLU L N 1 ATOM 3526 C CA . GLU B 2 195 ? -96.501 8.672 38.485 1.00 78.98 ? 195 GLU L CA 1 ATOM 3527 C C . GLU B 2 195 ? -95.637 9.049 39.685 1.00 79.64 ? 195 GLU L C 1 ATOM 3528 O O . GLU B 2 195 ? -95.847 8.543 40.790 1.00 80.35 ? 195 GLU L O 1 ATOM 3529 C CB . GLU B 2 195 ? -97.762 9.545 38.422 1.00 78.96 ? 195 GLU L CB 1 ATOM 3530 C CG . GLU B 2 195 ? -98.615 9.551 39.691 1.00 78.92 ? 195 GLU L CG 1 ATOM 3531 C CD . GLU B 2 195 ? -99.903 10.340 39.535 0.50 78.54 ? 195 GLU L CD 1 ATOM 3532 O OE1 . GLU B 2 195 ? -100.270 11.069 40.481 0.50 78.34 ? 195 GLU L OE1 1 ATOM 3533 O OE2 . GLU B 2 195 ? -100.550 10.233 38.472 0.50 78.15 ? 195 GLU L OE2 1 ATOM 3534 N N . ALA B 2 196 ? -94.663 9.928 39.461 1.00 79.37 ? 196 ALA L N 1 ATOM 3535 C CA . ALA B 2 196 ? -93.714 10.318 40.503 1.00 78.87 ? 196 ALA L CA 1 ATOM 3536 C C . ALA B 2 196 ? -93.707 11.833 40.709 1.00 79.05 ? 196 ALA L C 1 ATOM 3537 O O . ALA B 2 196 ? -93.263 12.585 39.838 1.00 79.03 ? 196 ALA L O 1 ATOM 3538 C CB . ALA B 2 196 ? -92.322 9.833 40.146 1.00 78.75 ? 196 ALA L CB 1 ATOM 3539 N N . THR B 2 197 ? -94.211 12.272 41.861 1.00 78.82 ? 197 THR L N 1 ATOM 3540 C CA . THR B 2 197 ? -94.132 13.677 42.251 1.00 78.10 ? 197 THR L CA 1 ATOM 3541 C C . THR B 2 197 ? -92.764 13.944 42.865 1.00 77.54 ? 197 THR L C 1 ATOM 3542 O O . THR B 2 197 ? -92.325 13.222 43.762 1.00 77.04 ? 197 THR L O 1 ATOM 3543 C CB . THR B 2 197 ? -95.221 14.053 43.272 1.00 78.14 ? 197 THR L CB 1 ATOM 3544 O OG1 . THR B 2 197 ? -95.192 13.134 44.370 1.00 78.43 ? 197 THR L OG1 1 ATOM 3545 C CG2 . THR B 2 197 ? -96.597 14.028 42.626 1.00 78.24 ? 197 THR L CG2 1 ATOM 3546 N N . HIS B 2 198 ? -92.095 14.983 42.372 1.00 77.24 ? 198 HIS L N 1 ATOM 3547 C CA . HIS B 2 198 ? -90.755 15.335 42.831 1.00 77.24 ? 198 HIS L CA 1 ATOM 3548 C C . HIS B 2 198 ? -90.602 16.854 42.860 1.00 77.00 ? 198 HIS L C 1 ATOM 3549 O O . HIS B 2 198 ? -91.370 17.572 42.223 1.00 77.09 ? 198 HIS L O 1 ATOM 3550 C CB . HIS B 2 198 ? -89.708 14.699 41.911 1.00 76.66 ? 198 HIS L CB 1 ATOM 3551 C CG . HIS B 2 198 ? -88.322 14.703 42.475 1.00 76.52 ? 198 HIS L CG 1 ATOM 3552 N ND1 . HIS B 2 198 ? -87.254 15.272 41.817 1.00 76.14 ? 198 HIS L ND1 1 ATOM 3553 C CD2 . HIS B 2 198 ? -87.831 14.215 43.639 1.00 75.99 ? 198 HIS L CD2 1 ATOM 3554 C CE1 . HIS B 2 198 ? -86.163 15.129 42.549 1.00 75.93 ? 198 HIS L CE1 1 ATOM 3555 N NE2 . HIS B 2 198 ? -86.486 14.493 43.660 1.00 75.43 ? 198 HIS L NE2 1 ATOM 3556 N N . LYS B 2 199 ? -89.615 17.333 43.614 1.00 77.00 ? 199 LYS L N 1 ATOM 3557 C CA . LYS B 2 199 ? -89.337 18.769 43.740 1.00 77.17 ? 199 LYS L CA 1 ATOM 3558 C C . LYS B 2 199 ? -88.952 19.415 42.403 1.00 76.94 ? 199 LYS L C 1 ATOM 3559 O O . LYS B 2 199 ? -89.202 20.601 42.189 1.00 75.94 ? 199 LYS L O 1 ATOM 3560 C CB . LYS B 2 199 ? -88.215 18.982 44.765 1.00 76.88 ? 199 LYS L CB 1 ATOM 3561 C CG . LYS B 2 199 ? -87.808 20.432 45.010 1.00 76.78 ? 199 LYS L CG 1 ATOM 3562 C CD . LYS B 2 199 ? -86.563 20.494 45.878 1.00 76.88 ? 199 LYS L CD 1 ATOM 3563 C CE . LYS B 2 199 ? -86.050 21.911 46.035 1.00 76.72 ? 199 LYS L CE 1 ATOM 3564 N NZ . LYS B 2 199 ? -84.653 21.933 46.556 1.00 76.53 ? 199 LYS L NZ 1 ATOM 3565 N N . THR B 2 200 ? -88.356 18.626 41.508 1.00 77.72 ? 200 THR L N 1 ATOM 3566 C CA . THR B 2 200 ? -87.808 19.136 40.248 1.00 78.19 ? 200 THR L CA 1 ATOM 3567 C C . THR B 2 200 ? -88.862 19.621 39.245 1.00 78.69 ? 200 THR L C 1 ATOM 3568 O O . THR B 2 200 ? -88.532 20.355 38.311 1.00 78.91 ? 200 THR L O 1 ATOM 3569 C CB . THR B 2 200 ? -86.931 18.071 39.555 1.00 78.23 ? 200 THR L CB 1 ATOM 3570 O OG1 . THR B 2 200 ? -87.668 16.851 39.420 1.00 78.92 ? 200 THR L OG1 1 ATOM 3571 C CG2 . THR B 2 200 ? -85.669 17.810 40.363 1.00 77.67 ? 200 THR L CG2 1 ATOM 3572 N N . SER B 2 201 ? -90.115 19.208 39.429 1.00 79.22 ? 201 SER L N 1 ATOM 3573 C CA . SER B 2 201 ? -91.209 19.621 38.542 1.00 79.37 ? 201 SER L CA 1 ATOM 3574 C C . SER B 2 201 ? -92.499 19.875 39.319 1.00 79.33 ? 201 SER L C 1 ATOM 3575 O O . SER B 2 201 ? -92.744 19.250 40.351 1.00 78.89 ? 201 SER L O 1 ATOM 3576 C CB . SER B 2 201 ? -91.451 18.553 37.471 1.00 79.70 ? 201 SER L CB 1 ATOM 3577 O OG . SER B 2 201 ? -91.582 17.265 38.052 1.00 79.90 ? 201 SER L OG 1 ATOM 3578 N N . THR B 2 202 ? -93.320 20.796 38.815 1.00 79.95 ? 202 THR L N 1 ATOM 3579 C CA . THR B 2 202 ? -94.615 21.095 39.426 1.00 80.30 ? 202 THR L CA 1 ATOM 3580 C C . THR B 2 202 ? -95.559 19.907 39.263 1.00 80.88 ? 202 THR L C 1 ATOM 3581 O O . THR B 2 202 ? -96.084 19.382 40.247 1.00 81.24 ? 202 THR L O 1 ATOM 3582 C CB . THR B 2 202 ? -95.267 22.343 38.797 1.00 80.66 ? 202 THR L CB 1 ATOM 3583 O OG1 . THR B 2 202 ? -94.373 23.459 38.896 1.00 81.00 ? 202 THR L OG1 1 ATOM 3584 C CG2 . THR B 2 202 ? -96.576 22.679 39.501 1.00 80.41 ? 202 THR L CG2 1 ATOM 3585 N N . SER B 2 203 ? -95.764 19.489 38.015 1.00 81.05 ? 203 SER L N 1 ATOM 3586 C CA . SER B 2 203 ? -96.604 18.332 37.704 1.00 80.89 ? 203 SER L CA 1 ATOM 3587 C C . SER B 2 203 ? -95.768 17.048 37.714 1.00 79.96 ? 203 SER L C 1 ATOM 3588 O O . SER B 2 203 ? -94.578 17.082 37.403 1.00 79.20 ? 203 SER L O 1 ATOM 3589 C CB . SER B 2 203 ? -97.283 18.516 36.342 1.00 81.40 ? 203 SER L CB 1 ATOM 3590 O OG . SER B 2 203 ? -96.345 18.879 35.344 1.00 81.80 ? 203 SER L OG 1 ATOM 3591 N N . PRO B 2 204 ? -96.394 15.910 38.067 1.00 80.32 ? 204 PRO L N 1 ATOM 3592 C CA . PRO B 2 204 ? -95.665 14.647 38.217 1.00 81.22 ? 204 PRO L CA 1 ATOM 3593 C C . PRO B 2 204 ? -95.232 14.017 36.890 1.00 81.46 ? 204 PRO L C 1 ATOM 3594 O O . PRO B 2 204 ? -95.918 14.166 35.877 1.00 81.53 ? 204 PRO L O 1 ATOM 3595 C CB . PRO B 2 204 ? -96.679 13.744 38.925 1.00 80.98 ? 204 PRO L CB 1 ATOM 3596 C CG . PRO B 2 204 ? -97.999 14.267 38.506 1.00 80.61 ? 204 PRO L CG 1 ATOM 3597 C CD . PRO B 2 204 ? -97.834 15.748 38.343 1.00 80.30 ? 204 PRO L CD 1 ATOM 3598 N N . ILE B 2 205 ? -94.099 13.318 36.915 1.00 81.50 ? 205 ILE L N 1 ATOM 3599 C CA . ILE B 2 205 ? -93.595 12.595 35.745 1.00 81.90 ? 205 ILE L CA 1 ATOM 3600 C C . ILE B 2 205 ? -94.259 11.215 35.678 1.00 81.96 ? 205 ILE L C 1 ATOM 3601 O O . ILE B 2 205 ? -94.231 10.459 36.651 1.00 81.88 ? 205 ILE L O 1 ATOM 3602 C CB . ILE B 2 205 ? -92.041 12.466 35.774 1.00 82.49 ? 205 ILE L CB 1 ATOM 3603 C CG1 . ILE B 2 205 ? -91.527 11.727 34.533 1.00 82.59 ? 205 ILE L CG1 1 ATOM 3604 C CG2 . ILE B 2 205 ? -91.568 11.763 37.044 1.00 82.86 ? 205 ILE L CG2 1 ATOM 3605 C CD1 . ILE B 2 205 ? -90.015 11.747 34.397 1.00 82.38 ? 205 ILE L CD1 1 ATOM 3606 N N . VAL B 2 206 ? -94.850 10.897 34.525 1.00 82.08 ? 206 VAL L N 1 ATOM 3607 C CA . VAL B 2 206 ? -95.719 9.724 34.389 1.00 81.88 ? 206 VAL L CA 1 ATOM 3608 C C . VAL B 2 206 ? -95.273 8.776 33.273 1.00 81.85 ? 206 VAL L C 1 ATOM 3609 O O . VAL B 2 206 ? -95.303 9.135 32.094 1.00 81.40 ? 206 VAL L O 1 ATOM 3610 C CB . VAL B 2 206 ? -97.174 10.154 34.108 1.00 81.18 ? 206 VAL L CB 1 ATOM 3611 C CG1 . VAL B 2 206 ? -98.072 8.937 33.944 1.00 80.99 ? 206 VAL L CG1 1 ATOM 3612 C CG2 . VAL B 2 206 ? -97.686 11.050 35.223 1.00 80.99 ? 206 VAL L CG2 1 ATOM 3613 N N . LYS B 2 207 ? -94.865 7.568 33.661 1.00 82.23 ? 207 LYS L N 1 ATOM 3614 C CA . LYS B 2 207 ? -94.618 6.475 32.716 1.00 82.27 ? 207 LYS L CA 1 ATOM 3615 C C . LYS B 2 207 ? -95.690 5.400 32.883 1.00 82.09 ? 207 LYS L C 1 ATOM 3616 O O . LYS B 2 207 ? -96.108 5.097 34.002 1.00 81.71 ? 207 LYS L O 1 ATOM 3617 C CB . LYS B 2 207 ? -93.219 5.876 32.919 1.00 82.21 ? 207 LYS L CB 1 ATOM 3618 C CG . LYS B 2 207 ? -92.199 6.281 31.855 1.00 82.28 ? 207 LYS L CG 1 ATOM 3619 C CD . LYS B 2 207 ? -91.995 7.791 31.786 1.00 82.38 ? 207 LYS L CD 1 ATOM 3620 C CE . LYS B 2 207 ? -91.006 8.167 30.692 1.00 82.38 ? 207 LYS L CE 1 ATOM 3621 N NZ . LYS B 2 207 ? -90.976 9.637 30.442 1.00 82.38 ? 207 LYS L NZ 1 ATOM 3622 N N . SER B 2 208 ? -96.130 4.832 31.762 1.00 82.57 ? 208 SER L N 1 ATOM 3623 C CA . SER B 2 208 ? -97.254 3.897 31.755 1.00 82.82 ? 208 SER L CA 1 ATOM 3624 C C . SER B 2 208 ? -97.119 2.862 30.639 1.00 82.86 ? 208 SER L C 1 ATOM 3625 O O . SER B 2 208 ? -96.269 2.995 29.757 1.00 82.64 ? 208 SER L O 1 ATOM 3626 C CB . SER B 2 208 ? -98.566 4.669 31.590 1.00 82.67 ? 208 SER L CB 1 ATOM 3627 O OG . SER B 2 208 ? -99.681 3.798 31.598 1.00 82.87 ? 208 SER L OG 1 ATOM 3628 N N . PHE B 2 209 ? -97.956 1.826 30.693 1.00 83.22 ? 209 PHE L N 1 ATOM 3629 C CA . PHE B 2 209 ? -98.012 0.814 29.633 1.00 83.69 ? 209 PHE L CA 1 ATOM 3630 C C . PHE B 2 209 ? -99.334 0.044 29.647 1.00 84.05 ? 209 PHE L C 1 ATOM 3631 O O . PHE B 2 209 ? -100.026 -0.001 30.665 1.00 83.94 ? 209 PHE L O 1 ATOM 3632 C CB . PHE B 2 209 ? -96.840 -0.170 29.758 1.00 82.94 ? 209 PHE L CB 1 ATOM 3633 C CG . PHE B 2 209 ? -97.067 -1.267 30.765 1.00 83.08 ? 209 PHE L CG 1 ATOM 3634 C CD1 . PHE B 2 209 ? -96.802 -1.060 32.113 1.00 82.98 ? 209 PHE L CD1 1 ATOM 3635 C CD2 . PHE B 2 209 ? -97.545 -2.510 30.362 1.00 82.96 ? 209 PHE L CD2 1 ATOM 3636 C CE1 . PHE B 2 209 ? -97.010 -2.073 33.043 1.00 82.84 ? 209 PHE L CE1 1 ATOM 3637 C CE2 . PHE B 2 209 ? -97.758 -3.523 31.286 1.00 82.86 ? 209 PHE L CE2 1 ATOM 3638 C CZ . PHE B 2 209 ? -97.489 -3.305 32.628 1.00 82.75 ? 209 PHE L CZ 1 ATOM 3639 N N . ASN B 2 210 ? -99.667 -0.557 28.507 1.00 84.74 ? 210 ASN L N 1 ATOM 3640 C CA . ASN B 2 210 ? -100.810 -1.461 28.396 1.00 85.50 ? 210 ASN L CA 1 ATOM 3641 C C . ASN B 2 210 ? -100.324 -2.879 28.116 1.00 86.14 ? 210 ASN L C 1 ATOM 3642 O O . ASN B 2 210 ? -99.451 -3.083 27.271 1.00 86.01 ? 210 ASN L O 1 ATOM 3643 C CB . ASN B 2 210 ? -101.745 -1.006 27.274 1.00 85.25 ? 210 ASN L CB 1 ATOM 3644 C CG . ASN B 2 210 ? -102.367 0.355 27.542 1.00 85.13 ? 210 ASN L CG 1 ATOM 3645 O OD1 . ASN B 2 210 ? -102.662 0.705 28.685 1.00 85.27 ? 210 ASN L OD1 1 ATOM 3646 N ND2 . ASN B 2 210 ? -102.576 1.128 26.482 1.00 84.96 ? 210 ASN L ND2 1 ATOM 3647 N N . ARG B 2 211 ? -100.887 -3.856 28.827 1.00 86.96 ? 211 ARG L N 1 ATOM 3648 C CA . ARG B 2 211 ? -100.484 -5.258 28.664 1.00 87.86 ? 211 ARG L CA 1 ATOM 3649 C C . ARG B 2 211 ? -100.932 -5.847 27.320 1.00 88.91 ? 211 ARG L C 1 ATOM 3650 O O . ARG B 2 211 ? -100.361 -6.833 26.852 1.00 88.93 ? 211 ARG L O 1 ATOM 3651 C CB . ARG B 2 211 ? -100.997 -6.120 29.829 1.00 87.46 ? 211 ARG L CB 1 ATOM 3652 C CG . ARG B 2 211 ? -102.514 -6.277 29.916 1.00 87.40 ? 211 ARG L CG 1 ATOM 3653 C CD . ARG B 2 211 ? -102.905 -7.101 31.139 1.00 87.39 ? 211 ARG L CD 1 ATOM 3654 N NE . ARG B 2 211 ? -104.340 -7.382 31.189 1.00 87.26 ? 211 ARG L NE 1 ATOM 3655 C CZ . ARG B 2 211 ? -104.959 -8.307 30.457 1.00 87.40 ? 211 ARG L CZ 1 ATOM 3656 N NH1 . ARG B 2 211 ? -104.283 -9.070 29.600 1.00 87.42 ? 211 ARG L NH1 1 ATOM 3657 N NH2 . ARG B 2 211 ? -106.272 -8.474 30.584 1.00 87.49 ? 211 ARG L NH2 1 ATOM 3658 N N . ASN B 2 212 ? -101.948 -5.239 26.707 1.00 90.01 ? 212 ASN L N 1 ATOM 3659 C CA . ASN B 2 212 ? -102.403 -5.640 25.374 1.00 91.13 ? 212 ASN L CA 1 ATOM 3660 C C . ASN B 2 212 ? -101.391 -5.258 24.295 1.00 92.19 ? 212 ASN L C 1 ATOM 3661 O O . ASN B 2 212 ? -101.039 -6.078 23.446 1.00 92.12 ? 212 ASN L O 1 ATOM 3662 C CB . ASN B 2 212 ? -103.758 -5.001 25.050 1.00 91.21 ? 212 ASN L CB 1 ATOM 3663 C CG . ASN B 2 212 ? -104.862 -5.458 25.988 1.00 91.37 ? 212 ASN L CG 1 ATOM 3664 O OD1 . ASN B 2 212 ? -104.609 -5.808 27.142 1.00 91.64 ? 212 ASN L OD1 1 ATOM 3665 N ND2 . ASN B 2 212 ? -106.097 -5.448 25.496 1.00 91.17 ? 212 ASN L ND2 1 ATOM 3666 N N . GLU B 2 213 ? -100.928 -4.010 24.340 1.00 93.41 ? 213 GLU L N 1 ATOM 3667 C CA . GLU B 2 213 ? -99.977 -3.490 23.355 1.00 94.63 ? 213 GLU L CA 1 ATOM 3668 C C . GLU B 2 213 ? -98.531 -3.665 23.826 1.00 96.18 ? 213 GLU L C 1 ATOM 3669 O O . GLU B 2 213 ? -98.041 -2.891 24.653 1.00 96.23 ? 213 GLU L O 1 ATOM 3670 C CB . GLU B 2 213 ? -100.257 -2.009 23.079 1.00 94.49 ? 213 GLU L CB 1 ATOM 3671 C CG . GLU B 2 213 ? -101.635 -1.735 22.482 1.00 94.38 ? 213 GLU L CG 1 ATOM 3672 C CD . GLU B 2 213 ? -101.879 -0.260 22.194 1.00 94.33 ? 213 GLU L CD 1 ATOM 3673 O OE1 . GLU B 2 213 ? -101.029 0.579 22.564 1.00 94.39 ? 213 GLU L OE1 1 ATOM 3674 O OE2 . GLU B 2 213 ? -102.927 0.060 21.596 1.00 94.06 ? 213 GLU L OE2 1 ATOM 3675 N N . CYS B 2 214 ? -97.856 -4.684 23.294 1.00 97.61 ? 214 CYS L N 1 ATOM 3676 C CA . CYS B 2 214 ? -96.442 -4.931 23.599 1.00 98.32 ? 214 CYS L CA 1 ATOM 3677 C C . CYS B 2 214 ? -95.534 -4.097 22.692 1.00 99.48 ? 214 CYS L C 1 ATOM 3678 O O . CYS B 2 214 ? -94.927 -3.117 23.132 1.00 100.01 ? 214 CYS L O 1 ATOM 3679 C CB . CYS B 2 214 ? -96.106 -6.420 23.445 1.00 100.70 ? 214 CYS L CB 1 ATOM 3680 S SG . CYS B 2 214 ? -96.847 -7.490 24.705 1.00 103.00 ? 214 CYS L SG 1 ATOM 3681 O OXT . CYS B 2 214 ? -95.383 -4.380 21.501 1.00 99.46 ? 214 CYS L OXT 1 ATOM 3682 N N . GLU C 3 1 ? -49.248 -7.958 50.298 1.00 83.16 ? 1 GLU H N 1 ATOM 3683 C CA . GLU C 3 1 ? -50.352 -7.116 50.838 1.00 83.11 ? 1 GLU H CA 1 ATOM 3684 C C . GLU C 3 1 ? -51.102 -7.855 51.939 1.00 83.06 ? 1 GLU H C 1 ATOM 3685 O O . GLU C 3 1 ? -51.326 -9.064 51.847 1.00 82.80 ? 1 GLU H O 1 ATOM 3686 C CB . GLU C 3 1 ? -51.320 -6.723 49.719 1.00 83.09 ? 1 GLU H CB 1 ATOM 3687 C CG . GLU C 3 1 ? -50.765 -5.673 48.764 0.50 83.26 ? 1 GLU H CG 1 ATOM 3688 C CD . GLU C 3 1 ? -51.584 -5.535 47.489 0.50 83.32 ? 1 GLU H CD 1 ATOM 3689 O OE1 . GLU C 3 1 ? -52.788 -5.872 47.504 0.50 83.66 ? 1 GLU H OE1 1 ATOM 3690 O OE2 . GLU C 3 1 ? -51.021 -5.084 46.469 0.50 83.00 ? 1 GLU H OE2 1 ATOM 3691 N N . VAL C 3 2 ? -51.496 -7.115 52.973 1.00 83.19 ? 2 VAL H N 1 ATOM 3692 C CA . VAL C 3 2 ? -52.206 -7.686 54.114 1.00 83.23 ? 2 VAL H CA 1 ATOM 3693 C C . VAL C 3 2 ? -53.631 -8.075 53.720 1.00 83.41 ? 2 VAL H C 1 ATOM 3694 O O . VAL C 3 2 ? -54.349 -7.287 53.105 1.00 83.69 ? 2 VAL H O 1 ATOM 3695 C CB . VAL C 3 2 ? -52.259 -6.694 55.292 1.00 83.15 ? 2 VAL H CB 1 ATOM 3696 C CG1 . VAL C 3 2 ? -53.014 -7.297 56.468 1.00 83.25 ? 2 VAL H CG1 1 ATOM 3697 C CG2 . VAL C 3 2 ? -50.851 -6.294 55.710 1.00 83.07 ? 2 VAL H CG2 1 ATOM 3698 N N . GLN C 3 3 ? -54.026 -9.297 54.071 1.00 83.56 ? 3 GLN H N 1 ATOM 3699 C CA . GLN C 3 3 ? -55.353 -9.816 53.748 1.00 83.63 ? 3 GLN H CA 1 ATOM 3700 C C . GLN C 3 3 ? -55.915 -10.606 54.926 1.00 83.70 ? 3 GLN H C 1 ATOM 3701 O O . GLN C 3 3 ? -55.286 -11.553 55.398 1.00 84.18 ? 3 GLN H O 1 ATOM 3702 C CB . GLN C 3 3 ? -55.280 -10.726 52.519 1.00 85.60 ? 3 GLN H CB 1 ATOM 3703 C CG . GLN C 3 3 ? -55.129 -9.991 51.183 1.00 86.99 ? 3 GLN H CG 1 ATOM 3704 C CD . GLN C 3 3 ? -56.440 -9.416 50.657 1.00 87.72 ? 3 GLN H CD 1 ATOM 3705 O OE1 . GLN C 3 3 ? -57.501 -9.581 51.266 1.00 88.73 ? 3 GLN H OE1 1 ATOM 3706 N NE2 . GLN C 3 3 ? -56.368 -8.739 49.515 1.00 86.47 ? 3 GLN H NE2 1 ATOM 3707 N N . LEU C 3 4 ? -57.089 -10.203 55.404 1.00 82.88 ? 4 LEU H N 1 ATOM 3708 C CA . LEU C 3 4 ? -57.847 -10.994 56.367 1.00 82.16 ? 4 LEU H CA 1 ATOM 3709 C C . LEU C 3 4 ? -59.080 -11.553 55.667 1.00 81.93 ? 4 LEU H C 1 ATOM 3710 O O . LEU C 3 4 ? -60.019 -10.814 55.369 1.00 81.74 ? 4 LEU H O 1 ATOM 3711 C CB . LEU C 3 4 ? -58.262 -10.140 57.569 1.00 81.27 ? 4 LEU H CB 1 ATOM 3712 C CG . LEU C 3 4 ? -57.147 -9.535 58.428 1.00 80.03 ? 4 LEU H CG 1 ATOM 3713 C CD1 . LEU C 3 4 ? -57.741 -8.939 59.689 1.00 78.88 ? 4 LEU H CD1 1 ATOM 3714 C CD2 . LEU C 3 4 ? -56.082 -10.564 58.779 1.00 80.24 ? 4 LEU H CD2 1 ATOM 3715 N N . GLN C 3 5 ? -59.065 -12.854 55.393 1.00 81.88 ? 5 GLN H N 1 ATOM 3716 C CA . GLN C 3 5 ? -60.146 -13.504 54.655 1.00 81.44 ? 5 GLN H CA 1 ATOM 3717 C C . GLN C 3 5 ? -61.044 -14.279 55.611 1.00 79.97 ? 5 GLN H C 1 ATOM 3718 O O . GLN C 3 5 ? -60.648 -15.315 56.141 1.00 79.20 ? 5 GLN H O 1 ATOM 3719 C CB . GLN C 3 5 ? -59.564 -14.439 53.585 1.00 81.76 ? 5 GLN H CB 1 ATOM 3720 C CG . GLN C 3 5 ? -60.594 -15.262 52.801 1.00 82.47 ? 5 GLN H CG 1 ATOM 3721 C CD . GLN C 3 5 ? -61.532 -14.414 51.955 1.00 83.98 ? 5 GLN H CD 1 ATOM 3722 O OE1 . GLN C 3 5 ? -61.345 -13.203 51.810 1.00 85.00 ? 5 GLN H OE1 1 ATOM 3723 N NE2 . GLN C 3 5 ? -62.547 -15.054 51.382 1.00 83.98 ? 5 GLN H NE2 1 ATOM 3724 N N . GLN C 3 6 ? -62.256 -13.771 55.820 1.00 80.09 ? 6 GLN H N 1 ATOM 3725 C CA . GLN C 3 6 ? -63.221 -14.401 56.718 1.00 81.41 ? 6 GLN H CA 1 ATOM 3726 C C . GLN C 3 6 ? -64.067 -15.468 56.010 1.00 81.01 ? 6 GLN H C 1 ATOM 3727 O O . GLN C 3 6 ? -64.067 -15.562 54.783 1.00 80.25 ? 6 GLN H O 1 ATOM 3728 C CB . GLN C 3 6 ? -64.120 -13.342 57.358 1.00 82.04 ? 6 GLN H CB 1 ATOM 3729 C CG . GLN C 3 6 ? -63.379 -12.396 58.293 1.00 82.25 ? 6 GLN H CG 1 ATOM 3730 C CD . GLN C 3 6 ? -64.288 -11.358 58.924 1.00 82.17 ? 6 GLN H CD 1 ATOM 3731 O OE1 . GLN C 3 6 ? -63.960 -10.173 58.962 1.00 81.85 ? 6 GLN H OE1 1 ATOM 3732 N NE2 . GLN C 3 6 ? -65.441 -11.797 59.417 1.00 82.86 ? 6 GLN H NE2 1 ATOM 3733 N N . SER C 3 7 ? -64.796 -16.254 56.803 1.00 81.44 ? 7 SER H N 1 ATOM 3734 C CA . SER C 3 7 ? -65.449 -17.478 56.326 1.00 82.14 ? 7 SER H CA 1 ATOM 3735 C C . SER C 3 7 ? -66.692 -17.257 55.464 1.00 82.38 ? 7 SER H C 1 ATOM 3736 O O . SER C 3 7 ? -67.050 -18.125 54.666 1.00 82.74 ? 7 SER H O 1 ATOM 3737 C CB . SER C 3 7 ? -65.816 -18.377 57.510 1.00 83.87 ? 7 SER H CB 1 ATOM 3738 O OG . SER C 3 7 ? -66.626 -17.687 58.447 1.00 85.37 ? 7 SER H OG 1 ATOM 3739 N N . GLY C 3 8 ? -67.362 -16.121 55.638 1.00 82.16 ? 8 GLY H N 1 ATOM 3740 C CA . GLY C 3 8 ? -68.516 -15.781 54.798 1.00 82.21 ? 8 GLY H CA 1 ATOM 3741 C C . GLY C 3 8 ? -69.859 -16.183 55.393 1.00 82.19 ? 8 GLY H C 1 ATOM 3742 O O . GLY C 3 8 ? -69.907 -16.857 56.423 1.00 82.17 ? 8 GLY H O 1 ATOM 3743 N N . PRO C 3 9 ? -70.963 -15.780 54.730 1.00 81.97 ? 9 PRO H N 1 ATOM 3744 C CA . PRO C 3 9 ? -72.339 -15.845 55.243 1.00 81.47 ? 9 PRO H CA 1 ATOM 3745 C C . PRO C 3 9 ? -72.715 -17.144 55.959 1.00 80.90 ? 9 PRO H C 1 ATOM 3746 O O . PRO C 3 9 ? -72.428 -18.233 55.462 1.00 80.78 ? 9 PRO H O 1 ATOM 3747 C CB . PRO C 3 9 ? -73.184 -15.685 53.979 1.00 81.83 ? 9 PRO H CB 1 ATOM 3748 C CG . PRO C 3 9 ? -72.355 -14.848 53.087 1.00 81.95 ? 9 PRO H CG 1 ATOM 3749 C CD . PRO C 3 9 ? -70.923 -15.218 53.365 1.00 81.89 ? 9 PRO H CD 1 ATOM 3750 N N . GLU C 3 10 ? -73.360 -17.009 57.117 1.00 80.73 ? 10 GLU H N 1 ATOM 3751 C CA . GLU C 3 10 ? -73.837 -18.150 57.898 1.00 80.48 ? 10 GLU H CA 1 ATOM 3752 C C . GLU C 3 10 ? -75.320 -17.990 58.232 1.00 79.00 ? 10 GLU H C 1 ATOM 3753 O O . GLU C 3 10 ? -75.772 -16.896 58.572 1.00 78.30 ? 10 GLU H O 1 ATOM 3754 C CB . GLU C 3 10 ? -73.038 -18.271 59.198 1.00 83.11 ? 10 GLU H CB 1 ATOM 3755 C CG . GLU C 3 10 ? -71.592 -18.729 59.015 1.00 86.17 ? 10 GLU H CG 1 ATOM 3756 C CD . GLU C 3 10 ? -71.451 -20.229 58.773 1.00 89.45 ? 10 GLU H CD 1 ATOM 3757 O OE1 . GLU C 3 10 ? -72.413 -20.988 59.030 1.00 90.64 ? 10 GLU H OE1 1 ATOM 3758 O OE2 . GLU C 3 10 ? -70.362 -20.651 58.327 1.00 90.85 ? 10 GLU H OE2 1 ATOM 3759 N N . LEU C 3 11 ? -76.070 -19.083 58.113 1.00 78.35 ? 11 LEU H N 1 ATOM 3760 C CA . LEU C 3 11 ? -77.441 -19.156 58.617 1.00 78.02 ? 11 LEU H CA 1 ATOM 3761 C C . LEU C 3 11 ? -77.520 -20.321 59.593 1.00 77.70 ? 11 LEU H C 1 ATOM 3762 O O . LEU C 3 11 ? -77.192 -21.454 59.235 1.00 77.99 ? 11 LEU H O 1 ATOM 3763 C CB . LEU C 3 11 ? -78.436 -19.354 57.470 1.00 77.73 ? 11 LEU H CB 1 ATOM 3764 C CG . LEU C 3 11 ? -79.883 -19.722 57.837 1.00 77.76 ? 11 LEU H CG 1 ATOM 3765 C CD1 . LEU C 3 11 ? -80.477 -18.741 58.834 1.00 77.41 ? 11 LEU H CD1 1 ATOM 3766 C CD2 . LEU C 3 11 ? -80.743 -19.796 56.589 1.00 77.66 ? 11 LEU H CD2 1 ATOM 3767 N N . VAL C 3 12 ? -77.949 -20.041 60.822 1.00 76.83 ? 12 VAL H N 1 ATOM 3768 C CA . VAL C 3 12 ? -77.950 -21.046 61.884 1.00 76.40 ? 12 VAL H CA 1 ATOM 3769 C C . VAL C 3 12 ? -79.240 -21.027 62.700 1.00 74.80 ? 12 VAL H C 1 ATOM 3770 O O . VAL C 3 12 ? -79.864 -19.980 62.877 1.00 73.58 ? 12 VAL H O 1 ATOM 3771 C CB . VAL C 3 12 ? -76.754 -20.847 62.835 1.00 77.55 ? 12 VAL H CB 1 ATOM 3772 C CG1 . VAL C 3 12 ? -75.444 -21.095 62.099 1.00 77.97 ? 12 VAL H CG1 1 ATOM 3773 C CG2 . VAL C 3 12 ? -76.776 -19.448 63.441 1.00 77.90 ? 12 VAL H CG2 1 ATOM 3774 N N . GLN C 3 13 ? -79.628 -22.200 63.194 1.00 74.73 ? 13 GLN H N 1 ATOM 3775 C CA . GLN C 3 13 ? -80.812 -22.338 64.036 1.00 75.01 ? 13 GLN H CA 1 ATOM 3776 C C . GLN C 3 13 ? -80.583 -21.633 65.372 1.00 74.44 ? 13 GLN H C 1 ATOM 3777 O O . GLN C 3 13 ? -79.445 -21.550 65.837 1.00 74.37 ? 13 GLN H O 1 ATOM 3778 C CB . GLN C 3 13 ? -81.115 -23.818 64.293 1.00 76.35 ? 13 GLN H CB 1 ATOM 3779 C CG . GLN C 3 13 ? -81.550 -24.601 63.059 1.00 77.81 ? 13 GLN H CG 1 ATOM 3780 C CD . GLN C 3 13 ? -83.047 -24.531 62.801 1.00 79.34 ? 13 GLN H CD 1 ATOM 3781 O OE1 . GLN C 3 13 ? -83.854 -24.527 63.734 1.00 79.94 ? 13 GLN H OE1 1 ATOM 3782 N NE2 . GLN C 3 13 ? -83.425 -24.492 61.529 1.00 79.79 ? 13 GLN H NE2 1 ATOM 3783 N N . PRO C 3 14 ? -81.658 -21.112 65.989 1.00 73.98 ? 14 PRO H N 1 ATOM 3784 C CA . PRO C 3 14 ? -81.542 -20.620 67.363 1.00 73.11 ? 14 PRO H CA 1 ATOM 3785 C C . PRO C 3 14 ? -81.060 -21.717 68.312 1.00 71.33 ? 14 PRO H C 1 ATOM 3786 O O . PRO C 3 14 ? -81.528 -22.852 68.233 1.00 70.53 ? 14 PRO H O 1 ATOM 3787 C CB . PRO C 3 14 ? -82.974 -20.194 67.711 1.00 73.76 ? 14 PRO H CB 1 ATOM 3788 C CG . PRO C 3 14 ? -83.630 -19.947 66.404 1.00 74.12 ? 14 PRO H CG 1 ATOM 3789 C CD . PRO C 3 14 ? -83.016 -20.922 65.449 1.00 74.24 ? 14 PRO H CD 1 ATOM 3790 N N . GLY C 3 15 ? -80.111 -21.380 69.180 1.00 71.13 ? 15 GLY H N 1 ATOM 3791 C CA . GLY C 3 15 ? -79.507 -22.353 70.086 1.00 71.27 ? 15 GLY H CA 1 ATOM 3792 C C . GLY C 3 15 ? -78.289 -23.054 69.508 1.00 70.35 ? 15 GLY H C 1 ATOM 3793 O O . GLY C 3 15 ? -77.500 -23.635 70.249 1.00 69.54 ? 15 GLY H O 1 ATOM 3794 N N . ALA C 3 16 ? -78.131 -23.000 68.186 1.00 71.00 ? 16 ALA H N 1 ATOM 3795 C CA . ALA C 3 16 ? -77.005 -23.646 67.512 1.00 71.06 ? 16 ALA H CA 1 ATOM 3796 C C . ALA C 3 16 ? -75.736 -22.812 67.649 1.00 70.37 ? 16 ALA H C 1 ATOM 3797 O O . ALA C 3 16 ? -75.751 -21.734 68.247 1.00 69.40 ? 16 ALA H O 1 ATOM 3798 C CB . ALA C 3 16 ? -77.330 -23.875 66.041 1.00 70.62 ? 16 ALA H CB 1 ATOM 3799 N N . SER C 3 17 ? -74.640 -23.323 67.091 1.00 71.05 ? 17 SER H N 1 ATOM 3800 C CA . SER C 3 17 ? -73.354 -22.633 67.122 1.00 71.93 ? 17 SER H CA 1 ATOM 3801 C C . SER C 3 17 ? -72.861 -22.283 65.719 1.00 72.30 ? 17 SER H C 1 ATOM 3802 O O . SER C 3 17 ? -73.403 -22.751 64.717 1.00 72.57 ? 17 SER H O 1 ATOM 3803 C CB . SER C 3 17 ? -72.307 -23.494 67.835 1.00 72.31 ? 17 SER H CB 1 ATOM 3804 O OG . SER C 3 17 ? -72.521 -23.503 69.235 1.00 72.29 ? 17 SER H OG 1 ATOM 3805 N N . VAL C 3 18 ? -71.832 -21.446 65.665 1.00 72.78 ? 18 VAL H N 1 ATOM 3806 C CA . VAL C 3 18 ? -71.180 -21.095 64.411 1.00 72.99 ? 18 VAL H CA 1 ATOM 3807 C C . VAL C 3 18 ? -69.728 -20.739 64.688 1.00 73.41 ? 18 VAL H C 1 ATOM 3808 O O . VAL C 3 18 ? -69.422 -20.113 65.701 1.00 73.58 ? 18 VAL H O 1 ATOM 3809 C CB . VAL C 3 18 ? -71.881 -19.907 63.721 1.00 73.07 ? 18 VAL H CB 1 ATOM 3810 C CG1 . VAL C 3 18 ? -71.613 -18.605 64.472 1.00 72.53 ? 18 VAL H CG1 1 ATOM 3811 C CG2 . VAL C 3 18 ? -71.429 -19.793 62.274 1.00 73.47 ? 18 VAL H CG2 1 ATOM 3812 N N . LYS C 3 19 ? -68.838 -21.148 63.789 1.00 74.15 ? 19 LYS H N 1 ATOM 3813 C CA . LYS C 3 19 ? -67.408 -20.920 63.959 1.00 74.51 ? 19 LYS H CA 1 ATOM 3814 C C . LYS C 3 19 ? -66.865 -20.113 62.780 1.00 75.12 ? 19 LYS H C 1 ATOM 3815 O O . LYS C 3 19 ? -66.645 -20.650 61.695 1.00 75.18 ? 19 LYS H O 1 ATOM 3816 C CB . LYS C 3 19 ? -66.676 -22.257 64.092 1.00 74.36 ? 19 LYS H CB 1 ATOM 3817 C CG . LYS C 3 19 ? -65.274 -22.148 64.664 1.00 74.34 ? 19 LYS H CG 1 ATOM 3818 C CD . LYS C 3 19 ? -64.663 -23.525 64.892 1.00 74.39 ? 19 LYS H CD 1 ATOM 3819 C CE . LYS C 3 19 ? -63.239 -23.427 65.409 1.00 74.46 ? 19 LYS H CE 1 ATOM 3820 N NZ . LYS C 3 19 ? -62.618 -24.770 65.585 1.00 74.57 ? 19 LYS H NZ 1 ATOM 3821 N N . ILE C 3 20 ? -66.669 -18.817 63.005 1.00 76.06 ? 20 ILE H N 1 ATOM 3822 C CA . ILE C 3 20 ? -66.153 -17.912 61.985 1.00 76.15 ? 20 ILE H CA 1 ATOM 3823 C C . ILE C 3 20 ? -64.633 -17.993 61.955 1.00 76.37 ? 20 ILE H C 1 ATOM 3824 O O . ILE C 3 20 ? -63.984 -17.796 62.982 1.00 76.67 ? 20 ILE H O 1 ATOM 3825 C CB . ILE C 3 20 ? -66.540 -16.443 62.278 1.00 76.94 ? 20 ILE H CB 1 ATOM 3826 C CG1 . ILE C 3 20 ? -68.054 -16.289 62.422 1.00 77.42 ? 20 ILE H CG1 1 ATOM 3827 C CG2 . ILE C 3 20 ? -66.033 -15.526 61.169 1.00 77.14 ? 20 ILE H CG2 1 ATOM 3828 C CD1 . ILE C 3 20 ? -68.485 -14.873 62.751 1.00 77.10 ? 20 ILE H CD1 1 ATOM 3829 N N . SER C 3 21 ? -64.071 -18.282 60.783 1.00 76.38 ? 21 SER H N 1 ATOM 3830 C CA . SER C 3 21 ? -62.618 -18.327 60.609 1.00 76.60 ? 21 SER H CA 1 ATOM 3831 C C . SER C 3 21 ? -62.123 -17.042 59.953 1.00 77.53 ? 21 SER H C 1 ATOM 3832 O O . SER C 3 21 ? -62.850 -16.413 59.187 1.00 77.80 ? 21 SER H O 1 ATOM 3833 C CB . SER C 3 21 ? -62.204 -19.544 59.773 1.00 75.56 ? 21 SER H CB 1 ATOM 3834 O OG . SER C 3 21 ? -62.592 -19.404 58.419 1.00 74.73 ? 21 SER H OG 1 ATOM 3835 N N . CYS C 3 22 ? -60.890 -16.658 60.276 1.00 78.21 ? 22 CYS H N 1 ATOM 3836 C CA . CYS C 3 22 ? -60.249 -15.481 59.695 1.00 76.91 ? 22 CYS H CA 1 ATOM 3837 C C . CYS C 3 22 ? -58.843 -15.869 59.232 1.00 75.65 ? 22 CYS H C 1 ATOM 3838 O O . CYS C 3 22 ? -57.875 -15.755 59.984 1.00 75.44 ? 22 CYS H O 1 ATOM 3839 C CB . CYS C 3 22 ? -60.208 -14.336 60.720 1.00 78.62 ? 22 CYS H CB 1 ATOM 3840 S SG . CYS C 3 22 ? -59.324 -12.826 60.194 1.00 80.41 ? 22 CYS H SG 1 ATOM 3841 N N . LYS C 3 23 ? -58.750 -16.357 57.997 1.00 75.16 ? 23 LYS H N 1 ATOM 3842 C CA . LYS C 3 23 ? -57.470 -16.762 57.417 1.00 76.21 ? 23 LYS H CA 1 ATOM 3843 C C . LYS C 3 23 ? -56.658 -15.531 57.033 1.00 75.92 ? 23 LYS H C 1 ATOM 3844 O O . LYS C 3 23 ? -57.074 -14.747 56.177 1.00 75.24 ? 23 LYS H O 1 ATOM 3845 C CB . LYS C 3 23 ? -57.687 -17.649 56.186 1.00 76.50 ? 23 LYS H CB 1 ATOM 3846 C CG . LYS C 3 23 ? -58.388 -18.968 56.488 1.00 76.59 ? 23 LYS H CG 1 ATOM 3847 C CD . LYS C 3 23 ? -58.864 -19.659 55.222 0.50 76.34 ? 23 LYS H CD 1 ATOM 3848 C CE . LYS C 3 23 ? -59.758 -20.844 55.546 0.50 76.36 ? 23 LYS H CE 1 ATOM 3849 N NZ . LYS C 3 23 ? -60.294 -21.490 54.320 0.50 76.52 ? 23 LYS H NZ 1 ATOM 3850 N N . THR C 3 24 ? -55.501 -15.369 57.674 1.00 76.48 ? 24 THR H N 1 ATOM 3851 C CA . THR C 3 24 ? -54.662 -14.188 57.490 1.00 76.68 ? 24 THR H CA 1 ATOM 3852 C C . THR C 3 24 ? -53.493 -14.492 56.564 1.00 76.77 ? 24 THR H C 1 ATOM 3853 O O . THR C 3 24 ? -53.088 -15.647 56.424 1.00 76.93 ? 24 THR H O 1 ATOM 3854 C CB . THR C 3 24 ? -54.094 -13.688 58.835 1.00 77.61 ? 24 THR H CB 1 ATOM 3855 O OG1 . THR C 3 24 ? -53.065 -14.578 59.286 1.00 79.02 ? 24 THR H OG1 1 ATOM 3856 C CG2 . THR C 3 24 ? -55.189 -13.592 59.895 1.00 76.62 ? 24 THR H CG2 1 ATOM 3857 N N . SER C 3 25 ? -52.956 -13.447 55.937 1.00 77.01 ? 25 SER H N 1 ATOM 3858 C CA . SER C 3 25 ? -51.752 -13.563 55.111 1.00 76.92 ? 25 SER H CA 1 ATOM 3859 C C . SER C 3 25 ? -51.124 -12.193 54.861 1.00 75.97 ? 25 SER H C 1 ATOM 3860 O O . SER C 3 25 ? -51.787 -11.162 54.994 1.00 75.08 ? 25 SER H O 1 ATOM 3861 C CB . SER C 3 25 ? -52.075 -14.232 53.773 1.00 78.62 ? 25 SER H CB 1 ATOM 3862 O OG . SER C 3 25 ? -52.997 -13.461 53.023 1.00 80.10 ? 25 SER H OG 1 ATOM 3863 N N . GLY C 3 26 ? -49.842 -12.196 54.502 1.00 76.21 ? 26 GLY H N 1 ATOM 3864 C CA . GLY C 3 26 ? -49.124 -10.968 54.156 1.00 76.74 ? 26 GLY H CA 1 ATOM 3865 C C . GLY C 3 26 ? -48.456 -10.267 55.328 1.00 77.27 ? 26 GLY H C 1 ATOM 3866 O O . GLY C 3 26 ? -48.006 -9.128 55.195 1.00 77.97 ? 26 GLY H O 1 ATOM 3867 N N . TYR C 3 27 ? -48.394 -10.938 56.476 1.00 76.99 ? 27 TYR H N 1 ATOM 3868 C CA . TYR C 3 27 ? -47.694 -10.409 57.648 1.00 76.69 ? 27 TYR H CA 1 ATOM 3869 C C . TYR C 3 27 ? -47.420 -11.531 58.649 1.00 75.87 ? 27 TYR H C 1 ATOM 3870 O O . TYR C 3 27 ? -47.966 -12.629 58.526 1.00 75.07 ? 27 TYR H O 1 ATOM 3871 C CB . TYR C 3 27 ? -48.518 -9.305 58.313 1.00 77.25 ? 27 TYR H CB 1 ATOM 3872 C CG . TYR C 3 27 ? -49.741 -9.820 59.028 1.00 77.36 ? 27 TYR H CG 1 ATOM 3873 C CD1 . TYR C 3 27 ? -50.903 -10.121 58.331 1.00 77.37 ? 27 TYR H CD1 1 ATOM 3874 C CD2 . TYR C 3 27 ? -49.730 -10.022 60.401 1.00 77.55 ? 27 TYR H CD2 1 ATOM 3875 C CE1 . TYR C 3 27 ? -52.026 -10.603 58.984 1.00 77.27 ? 27 TYR H CE1 1 ATOM 3876 C CE2 . TYR C 3 27 ? -50.847 -10.505 61.066 1.00 77.70 ? 27 TYR H CE2 1 ATOM 3877 C CZ . TYR C 3 27 ? -51.993 -10.793 60.354 1.00 77.54 ? 27 TYR H CZ 1 ATOM 3878 O OH . TYR C 3 27 ? -53.102 -11.271 61.016 1.00 77.72 ? 27 TYR H OH 1 ATOM 3879 N N . THR C 3 28 ? -46.580 -11.247 59.640 1.00 76.19 ? 28 THR H N 1 ATOM 3880 C CA . THR C 3 28 ? -46.282 -12.216 60.694 1.00 76.60 ? 28 THR H CA 1 ATOM 3881 C C . THR C 3 28 ? -47.483 -12.353 61.634 1.00 77.33 ? 28 THR H C 1 ATOM 3882 O O . THR C 3 28 ? -47.800 -11.436 62.395 1.00 78.03 ? 28 THR H O 1 ATOM 3883 C CB . THR C 3 28 ? -45.039 -11.812 61.507 1.00 76.20 ? 28 THR H CB 1 ATOM 3884 O OG1 . THR C 3 28 ? -43.961 -11.500 60.616 1.00 76.09 ? 28 THR H OG1 1 ATOM 3885 C CG2 . THR C 3 28 ? -44.619 -12.943 62.433 1.00 76.25 ? 28 THR H CG2 1 ATOM 3886 N N . PHE C 3 29 ? -48.141 -13.506 61.572 1.00 76.74 ? 29 PHE H N 1 ATOM 3887 C CA . PHE C 3 29 ? -49.375 -13.754 62.318 1.00 76.52 ? 29 PHE H CA 1 ATOM 3888 C C . PHE C 3 29 ? -49.214 -13.557 63.831 1.00 77.16 ? 29 PHE H C 1 ATOM 3889 O O . PHE C 3 29 ? -50.110 -13.021 64.487 1.00 77.62 ? 29 PHE H O 1 ATOM 3890 C CB . PHE C 3 29 ? -49.872 -15.172 62.020 1.00 76.37 ? 29 PHE H CB 1 ATOM 3891 C CG . PHE C 3 29 ? -51.107 -15.558 62.781 1.00 76.36 ? 29 PHE H CG 1 ATOM 3892 C CD1 . PHE C 3 29 ? -52.326 -14.964 62.498 1.00 76.24 ? 29 PHE H CD1 1 ATOM 3893 C CD2 . PHE C 3 29 ? -51.051 -16.528 63.772 1.00 76.37 ? 29 PHE H CD2 1 ATOM 3894 C CE1 . PHE C 3 29 ? -53.468 -15.324 63.193 1.00 76.26 ? 29 PHE H CE1 1 ATOM 3895 C CE2 . PHE C 3 29 ? -52.186 -16.893 64.469 1.00 76.34 ? 29 PHE H CE2 1 ATOM 3896 C CZ . PHE C 3 29 ? -53.398 -16.290 64.180 1.00 76.28 ? 29 PHE H CZ 1 ATOM 3897 N N . SER C 3 30 ? -48.070 -13.978 64.369 1.00 76.66 ? 30 SER H N 1 ATOM 3898 C CA . SER C 3 30 ? -47.818 -13.931 65.813 1.00 76.17 ? 30 SER H CA 1 ATOM 3899 C C . SER C 3 30 ? -47.339 -12.564 66.316 1.00 76.21 ? 30 SER H C 1 ATOM 3900 O O . SER C 3 30 ? -47.125 -12.391 67.517 1.00 77.31 ? 30 SER H O 1 ATOM 3901 C CB . SER C 3 30 ? -46.790 -15.000 66.203 1.00 77.30 ? 30 SER H CB 1 ATOM 3902 O OG . SER C 3 30 ? -47.271 -16.302 65.916 1.00 78.03 ? 30 SER H OG 1 ATOM 3903 N N . GLU C 3 31 ? -47.162 -11.602 65.412 1.00 75.18 ? 31 GLU H N 1 ATOM 3904 C CA . GLU C 3 31 ? -46.684 -10.273 65.793 1.00 74.72 ? 31 GLU H CA 1 ATOM 3905 C C . GLU C 3 31 ? -47.778 -9.428 66.437 1.00 73.91 ? 31 GLU H C 1 ATOM 3906 O O . GLU C 3 31 ? -47.511 -8.684 67.375 1.00 74.18 ? 31 GLU H O 1 ATOM 3907 C CB . GLU C 3 31 ? -46.115 -9.534 64.580 1.00 74.64 ? 31 GLU H CB 1 ATOM 3908 C CG . GLU C 3 31 ? -45.457 -8.193 64.919 1.00 74.82 ? 31 GLU H CG 1 ATOM 3909 C CD . GLU C 3 31 ? -44.931 -7.456 63.698 1.00 74.74 ? 31 GLU H CD 1 ATOM 3910 O OE1 . GLU C 3 31 ? -44.684 -6.237 63.807 1.00 73.99 ? 31 GLU H OE1 1 ATOM 3911 O OE2 . GLU C 3 31 ? -44.766 -8.087 62.631 1.00 75.42 ? 31 GLU H OE2 1 ATOM 3912 N N . PHE C 3 32 ? -49.002 -9.537 65.926 1.00 73.97 ? 32 PHE H N 1 ATOM 3913 C CA . PHE C 3 32 ? -50.102 -8.681 66.370 1.00 74.61 ? 32 PHE H CA 1 ATOM 3914 C C . PHE C 3 32 ? -51.208 -9.470 67.057 1.00 73.72 ? 32 PHE H C 1 ATOM 3915 O O . PHE C 3 32 ? -51.449 -10.631 66.734 1.00 72.29 ? 32 PHE H O 1 ATOM 3916 C CB . PHE C 3 32 ? -50.700 -7.932 65.182 1.00 75.18 ? 32 PHE H CB 1 ATOM 3917 C CG . PHE C 3 32 ? -49.683 -7.242 64.324 1.00 75.18 ? 32 PHE H CG 1 ATOM 3918 C CD1 . PHE C 3 32 ? -49.435 -7.680 63.030 1.00 75.15 ? 32 PHE H CD1 1 ATOM 3919 C CD2 . PHE C 3 32 ? -48.976 -6.156 64.807 1.00 75.34 ? 32 PHE H CD2 1 ATOM 3920 C CE1 . PHE C 3 32 ? -48.498 -7.044 62.234 1.00 75.37 ? 32 PHE H CE1 1 ATOM 3921 C CE2 . PHE C 3 32 ? -48.035 -5.513 64.020 1.00 75.44 ? 32 PHE H CE2 1 ATOM 3922 C CZ . PHE C 3 32 ? -47.794 -5.958 62.730 1.00 75.49 ? 32 PHE H CZ 1 ATOM 3923 N N . THR C 3 33 ? -51.884 -8.821 68.002 1.00 74.71 ? 33 THR H N 1 ATOM 3924 C CA . THR C 3 33 ? -53.072 -9.386 68.629 1.00 75.89 ? 33 THR H CA 1 ATOM 3925 C C . THR C 3 33 ? -54.245 -9.319 67.653 1.00 76.96 ? 33 THR H C 1 ATOM 3926 O O . THR C 3 33 ? -54.397 -8.337 66.921 1.00 76.53 ? 33 THR H O 1 ATOM 3927 C CB . THR C 3 33 ? -53.445 -8.631 69.921 1.00 75.04 ? 33 THR H CB 1 ATOM 3928 O OG1 . THR C 3 33 ? -52.326 -8.631 70.819 1.00 74.39 ? 33 THR H OG1 1 ATOM 3929 C CG2 . THR C 3 33 ? -54.646 -9.279 70.600 1.00 74.55 ? 33 THR H CG2 1 ATOM 3930 N N . MET C 3 34 ? -55.055 -10.376 67.636 1.00 77.85 ? 34 MET H N 1 ATOM 3931 C CA . MET C 3 34 ? -56.234 -10.433 66.783 1.00 77.42 ? 34 MET H CA 1 ATOM 3932 C C . MET C 3 34 ? -57.462 -10.046 67.592 1.00 77.25 ? 34 MET H C 1 ATOM 3933 O O . MET C 3 34 ? -57.767 -10.670 68.608 1.00 76.62 ? 34 MET H O 1 ATOM 3934 C CB . MET C 3 34 ? -56.413 -11.838 66.211 1.00 78.49 ? 34 MET H CB 1 ATOM 3935 C CG . MET C 3 34 ? -57.545 -11.964 65.193 1.00 79.45 ? 34 MET H CG 1 ATOM 3936 S SD . MET C 3 34 ? -57.297 -10.962 63.711 1.00 82.08 ? 34 MET H SD 1 ATOM 3937 C CE . MET C 3 34 ? -55.815 -11.708 63.028 1.00 81.37 ? 34 MET H CE 1 ATOM 3938 N N . HIS C 3 35 ? -58.159 -9.010 67.134 1.00 77.61 ? 35 HIS H N 1 ATOM 3939 C CA . HIS C 3 35 ? -59.374 -8.536 67.783 1.00 77.75 ? 35 HIS H CA 1 ATOM 3940 C C . HIS C 3 35 ? -60.594 -8.931 66.969 1.00 77.91 ? 35 HIS H C 1 ATOM 3941 O O . HIS C 3 35 ? -60.505 -9.136 65.757 1.00 78.27 ? 35 HIS H O 1 ATOM 3942 C CB . HIS C 3 35 ? -59.325 -7.016 67.946 1.00 78.76 ? 35 HIS H CB 1 ATOM 3943 C CG . HIS C 3 35 ? -58.155 -6.538 68.748 1.00 78.67 ? 35 HIS H CG 1 ATOM 3944 N ND1 . HIS C 3 35 ? -58.131 -6.577 70.124 1.00 78.62 ? 35 HIS H ND1 1 ATOM 3945 C CD2 . HIS C 3 35 ? -56.963 -6.025 68.365 1.00 79.28 ? 35 HIS H CD2 1 ATOM 3946 C CE1 . HIS C 3 35 ? -56.979 -6.100 70.557 1.00 79.10 ? 35 HIS H CE1 1 ATOM 3947 N NE2 . HIS C 3 35 ? -56.251 -5.759 69.509 1.00 79.65 ? 35 HIS H NE2 1 ATOM 3948 N N . TRP C 3 36 ? -61.735 -9.039 67.643 1.00 77.78 ? 36 TRP H N 1 ATOM 3949 C CA . TRP C 3 36 ? -62.991 -9.359 66.981 1.00 77.07 ? 36 TRP H CA 1 ATOM 3950 C C . TRP C 3 36 ? -64.046 -8.334 67.343 1.00 76.38 ? 36 TRP H C 1 ATOM 3951 O O . TRP C 3 36 ? -64.263 -8.051 68.518 1.00 76.97 ? 36 TRP H O 1 ATOM 3952 C CB . TRP C 3 36 ? -63.456 -10.758 67.373 1.00 77.46 ? 36 TRP H CB 1 ATOM 3953 C CG . TRP C 3 36 ? -62.592 -11.817 66.811 1.00 77.33 ? 36 TRP H CG 1 ATOM 3954 C CD1 . TRP C 3 36 ? -61.413 -12.264 67.322 1.00 77.46 ? 36 TRP H CD1 1 ATOM 3955 C CD2 . TRP C 3 36 ? -62.819 -12.557 65.609 1.00 77.13 ? 36 TRP H CD2 1 ATOM 3956 N NE1 . TRP C 3 36 ? -60.892 -13.248 66.518 1.00 77.59 ? 36 TRP H NE1 1 ATOM 3957 C CE2 . TRP C 3 36 ? -61.735 -13.448 65.458 1.00 77.36 ? 36 TRP H CE2 1 ATOM 3958 C CE3 . TRP C 3 36 ? -63.834 -12.557 64.646 1.00 77.25 ? 36 TRP H CE3 1 ATOM 3959 C CZ2 . TRP C 3 36 ? -61.637 -14.332 64.383 1.00 77.44 ? 36 TRP H CZ2 1 ATOM 3960 C CZ3 . TRP C 3 36 ? -63.738 -13.437 63.577 1.00 77.41 ? 36 TRP H CZ3 1 ATOM 3961 C CH2 . TRP C 3 36 ? -62.646 -14.313 63.454 1.00 77.52 ? 36 TRP H CH2 1 ATOM 3962 N N . VAL C 3 37 ? -64.695 -7.780 66.322 1.00 75.92 ? 37 VAL H N 1 ATOM 3963 C CA . VAL C 3 37 ? -65.707 -6.752 66.509 1.00 76.02 ? 37 VAL H CA 1 ATOM 3964 C C . VAL C 3 37 ? -67.042 -7.221 65.946 1.00 75.81 ? 37 VAL H C 1 ATOM 3965 O O . VAL C 3 37 ? -67.083 -7.979 64.982 1.00 75.60 ? 37 VAL H O 1 ATOM 3966 C CB . VAL C 3 37 ? -65.285 -5.431 65.830 1.00 74.67 ? 37 VAL H CB 1 ATOM 3967 C CG1 . VAL C 3 37 ? -66.458 -4.460 65.747 1.00 74.22 ? 37 VAL H CG1 1 ATOM 3968 C CG2 . VAL C 3 37 ? -64.120 -4.805 66.581 1.00 73.53 ? 37 VAL H CG2 1 ATOM 3969 N N . LYS C 3 38 ? -68.125 -6.771 66.573 1.00 76.50 ? 38 LYS H N 1 ATOM 3970 C CA . LYS C 3 38 ? -69.481 -7.053 66.119 1.00 76.52 ? 38 LYS H CA 1 ATOM 3971 C C . LYS C 3 38 ? -70.140 -5.752 65.677 1.00 76.71 ? 38 LYS H C 1 ATOM 3972 O O . LYS C 3 38 ? -69.964 -4.715 66.314 1.00 76.75 ? 38 LYS H O 1 ATOM 3973 C CB . LYS C 3 38 ? -70.286 -7.689 67.254 1.00 76.07 ? 38 LYS H CB 1 ATOM 3974 C CG . LYS C 3 38 ? -71.763 -7.900 66.958 1.00 76.34 ? 38 LYS H CG 1 ATOM 3975 C CD . LYS C 3 38 ? -72.467 -8.573 68.128 1.00 76.55 ? 38 LYS H CD 1 ATOM 3976 C CE . LYS C 3 38 ? -73.980 -8.536 67.970 1.00 76.43 ? 38 LYS H CE 1 ATOM 3977 N NZ . LYS C 3 38 ? -74.675 -9.189 69.112 1.00 76.24 ? 38 LYS H NZ 1 ATOM 3978 N N . GLN C 3 39 ? -70.890 -5.809 64.580 1.00 77.35 ? 39 GLN H N 1 ATOM 3979 C CA . GLN C 3 39 ? -71.701 -4.678 64.152 1.00 77.82 ? 39 GLN H CA 1 ATOM 3980 C C . GLN C 3 39 ? -73.133 -5.127 63.907 1.00 78.48 ? 39 GLN H C 1 ATOM 3981 O O . GLN C 3 39 ? -73.398 -5.918 63.003 1.00 78.11 ? 39 GLN H O 1 ATOM 3982 C CB . GLN C 3 39 ? -71.128 -4.031 62.890 1.00 77.35 ? 39 GLN H CB 1 ATOM 3983 C CG . GLN C 3 39 ? -71.828 -2.724 62.520 1.00 77.42 ? 39 GLN H CG 1 ATOM 3984 C CD . GLN C 3 39 ? -71.063 -1.897 61.504 1.00 77.17 ? 39 GLN H CD 1 ATOM 3985 O OE1 . GLN C 3 39 ? -70.376 -2.434 60.637 1.00 76.98 ? 39 GLN H OE1 1 ATOM 3986 N NE2 . GLN C 3 39 ? -71.191 -0.579 61.602 1.00 76.77 ? 39 GLN H NE2 1 ATOM 3987 N N . SER C 3 40 ? -74.050 -4.622 64.727 1.00 79.88 ? 40 SER H N 1 ATOM 3988 C CA . SER C 3 40 ? -75.475 -4.872 64.538 1.00 80.47 ? 40 SER H CA 1 ATOM 3989 C C . SER C 3 40 ? -75.964 -4.122 63.309 1.00 81.25 ? 40 SER H C 1 ATOM 3990 O O . SER C 3 40 ? -75.289 -3.216 62.817 1.00 81.60 ? 40 SER H O 1 ATOM 3991 C CB . SER C 3 40 ? -76.266 -4.419 65.765 1.00 80.66 ? 40 SER H CB 1 ATOM 3992 O OG . SER C 3 40 ? -76.056 -3.041 66.019 1.00 81.11 ? 40 SER H OG 1 ATOM 3993 N N . HIS C 3 41 ? -77.148 -4.487 62.829 1.00 81.72 ? 41 HIS H N 1 ATOM 3994 C CA . HIS C 3 41 ? -77.703 -3.878 61.622 1.00 82.25 ? 41 HIS H CA 1 ATOM 3995 C C . HIS C 3 41 ? -78.159 -2.436 61.858 1.00 82.29 ? 41 HIS H C 1 ATOM 3996 O O . HIS C 3 41 ? -78.402 -1.696 60.906 1.00 82.58 ? 41 HIS H O 1 ATOM 3997 C CB . HIS C 3 41 ? -78.841 -4.735 61.070 1.00 84.91 ? 41 HIS H CB 1 ATOM 3998 C CG . HIS C 3 41 ? -78.416 -6.125 60.706 1.00 86.54 ? 41 HIS H CG 1 ATOM 3999 N ND1 . HIS C 3 41 ? -78.899 -7.245 61.349 1.00 86.83 ? 41 HIS H ND1 1 ATOM 4000 C CD2 . HIS C 3 41 ? -77.529 -6.574 59.785 1.00 86.74 ? 41 HIS H CD2 1 ATOM 4001 C CE1 . HIS C 3 41 ? -78.342 -8.324 60.828 1.00 86.61 ? 41 HIS H CE1 1 ATOM 4002 N NE2 . HIS C 3 41 ? -77.506 -7.944 59.878 1.00 86.82 ? 41 HIS H NE2 1 ATOM 4003 N N . GLY C 3 42 ? -78.255 -2.040 63.128 1.00 82.19 ? 42 GLY H N 1 ATOM 4004 C CA . GLY C 3 42 ? -78.430 -0.636 63.497 1.00 81.93 ? 42 GLY H CA 1 ATOM 4005 C C . GLY C 3 42 ? -77.155 0.189 63.374 1.00 81.69 ? 42 GLY H C 1 ATOM 4006 O O . GLY C 3 42 ? -77.165 1.388 63.657 1.00 81.78 ? 42 GLY H O 1 ATOM 4007 N N . LYS C 3 43 ? -76.058 -0.455 62.967 1.00 81.50 ? 43 LYS H N 1 ATOM 4008 C CA . LYS C 3 43 ? -74.777 0.211 62.699 1.00 81.70 ? 43 LYS H CA 1 ATOM 4009 C C . LYS C 3 43 ? -74.144 0.781 63.968 1.00 82.22 ? 43 LYS H C 1 ATOM 4010 O O . LYS C 3 43 ? -73.953 1.993 64.094 1.00 83.14 ? 43 LYS H O 1 ATOM 4011 C CB . LYS C 3 43 ? -74.925 1.309 61.631 1.00 82.40 ? 43 LYS H CB 1 ATOM 4012 C CG . LYS C 3 43 ? -75.479 0.821 60.300 1.00 82.65 ? 43 LYS H CG 1 ATOM 4013 C CD . LYS C 3 43 ? -75.644 1.970 59.314 0.50 82.34 ? 43 LYS H CD 1 ATOM 4014 C CE . LYS C 3 43 ? -76.302 1.510 58.021 0.50 82.51 ? 43 LYS H CE 1 ATOM 4015 N NZ . LYS C 3 43 ? -76.582 2.646 57.097 0.50 82.56 ? 43 LYS H NZ 1 ATOM 4016 N N . SER C 3 44 ? -73.825 -0.107 64.907 1.00 81.50 ? 44 SER H N 1 ATOM 4017 C CA . SER C 3 44 ? -73.073 0.263 66.106 1.00 80.12 ? 44 SER H CA 1 ATOM 4018 C C . SER C 3 44 ? -72.023 -0.808 66.396 1.00 79.30 ? 44 SER H C 1 ATOM 4019 O O . SER C 3 44 ? -72.359 -1.970 66.641 1.00 79.17 ? 44 SER H O 1 ATOM 4020 C CB . SER C 3 44 ? -74.009 0.448 67.310 1.00 80.26 ? 44 SER H CB 1 ATOM 4021 O OG . SER C 3 44 ? -74.551 -0.786 67.750 1.00 80.33 ? 44 SER H OG 1 ATOM 4022 N N . LEU C 3 45 ? -70.755 -0.407 66.354 1.00 78.28 ? 45 LEU H N 1 ATOM 4023 C CA . LEU C 3 45 ? -69.644 -1.338 66.524 1.00 77.03 ? 45 LEU H CA 1 ATOM 4024 C C . LEU C 3 45 ? -69.450 -1.687 67.993 1.00 75.80 ? 45 LEU H C 1 ATOM 4025 O O . LEU C 3 45 ? -69.752 -0.883 68.878 1.00 74.52 ? 45 LEU H O 1 ATOM 4026 C CB . LEU C 3 45 ? -68.358 -0.745 65.949 1.00 76.01 ? 45 LEU H CB 1 ATOM 4027 C CG . LEU C 3 45 ? -68.370 -0.525 64.434 1.00 75.15 ? 45 LEU H CG 1 ATOM 4028 C CD1 . LEU C 3 45 ? -67.273 0.438 64.016 1.00 75.12 ? 45 LEU H CD1 1 ATOM 4029 C CD2 . LEU C 3 45 ? -68.236 -1.851 63.705 1.00 74.72 ? 45 LEU H CD2 1 ATOM 4030 N N . GLU C 3 46 ? -68.944 -2.893 68.239 1.00 75.71 ? 46 GLU H N 1 ATOM 4031 C CA . GLU C 3 46 ? -68.787 -3.407 69.593 1.00 75.48 ? 46 GLU H CA 1 ATOM 4032 C C . GLU C 3 46 ? -67.657 -4.438 69.647 1.00 74.54 ? 46 GLU H C 1 ATOM 4033 O O . GLU C 3 46 ? -67.709 -5.465 68.965 1.00 74.20 ? 46 GLU H O 1 ATOM 4034 C CB . GLU C 3 46 ? -70.104 -4.031 70.065 1.00 75.82 ? 46 GLU H CB 1 ATOM 4035 C CG . GLU C 3 46 ? -70.241 -4.150 71.577 1.00 76.39 ? 46 GLU H CG 1 ATOM 4036 C CD . GLU C 3 46 ? -71.664 -4.470 72.019 1.00 77.43 ? 46 GLU H CD 1 ATOM 4037 O OE1 . GLU C 3 46 ? -72.005 -4.185 73.186 1.00 78.29 ? 46 GLU H OE1 1 ATOM 4038 O OE2 . GLU C 3 46 ? -72.445 -5.002 71.200 1.00 79.04 ? 46 GLU H OE2 1 ATOM 4039 N N . TRP C 3 47 ? -66.636 -4.146 70.451 1.00 73.38 ? 47 TRP H N 1 ATOM 4040 C CA . TRP C 3 47 ? -65.481 -5.033 70.615 1.00 73.26 ? 47 TRP H CA 1 ATOM 4041 C C . TRP C 3 47 ? -65.878 -6.289 71.387 1.00 72.96 ? 47 TRP H C 1 ATOM 4042 O O . TRP C 3 47 ? -66.319 -6.202 72.530 1.00 74.03 ? 47 TRP H O 1 ATOM 4043 C CB . TRP C 3 47 ? -64.371 -4.292 71.364 1.00 72.62 ? 47 TRP H CB 1 ATOM 4044 C CG . TRP C 3 47 ? -63.106 -5.069 71.545 1.00 72.56 ? 47 TRP H CG 1 ATOM 4045 C CD1 . TRP C 3 47 ? -62.177 -5.347 70.593 1.00 72.62 ? 47 TRP H CD1 1 ATOM 4046 C CD2 . TRP C 3 47 ? -62.616 -5.641 72.763 1.00 72.48 ? 47 TRP H CD2 1 ATOM 4047 N NE1 . TRP C 3 47 ? -61.143 -6.066 71.135 1.00 72.66 ? 47 TRP H NE1 1 ATOM 4048 C CE2 . TRP C 3 47 ? -61.389 -6.261 72.468 1.00 72.41 ? 47 TRP H CE2 1 ATOM 4049 C CE3 . TRP C 3 47 ? -63.101 -5.695 74.074 1.00 72.91 ? 47 TRP H CE3 1 ATOM 4050 C CZ2 . TRP C 3 47 ? -60.635 -6.927 73.435 1.00 72.51 ? 47 TRP H CZ2 1 ATOM 4051 C CZ3 . TRP C 3 47 ? -62.350 -6.358 75.036 1.00 72.65 ? 47 TRP H CZ3 1 ATOM 4052 C CH2 . TRP C 3 47 ? -61.132 -6.965 74.710 1.00 72.54 ? 47 TRP H CH2 1 ATOM 4053 N N . ILE C 3 48 ? -65.729 -7.451 70.756 1.00 72.07 ? 48 ILE H N 1 ATOM 4054 C CA . ILE C 3 48 ? -66.070 -8.725 71.393 1.00 72.47 ? 48 ILE H CA 1 ATOM 4055 C C . ILE C 3 48 ? -64.954 -9.138 72.336 1.00 72.92 ? 48 ILE H C 1 ATOM 4056 O O . ILE C 3 48 ? -65.181 -9.425 73.513 1.00 72.10 ? 48 ILE H O 1 ATOM 4057 C CB . ILE C 3 48 ? -66.264 -9.848 70.356 1.00 71.69 ? 48 ILE H CB 1 ATOM 4058 C CG1 . ILE C 3 48 ? -67.443 -9.533 69.439 1.00 71.80 ? 48 ILE H CG1 1 ATOM 4059 C CG2 . ILE C 3 48 ? -66.496 -11.183 71.050 1.00 71.70 ? 48 ILE H CG2 1 ATOM 4060 C CD1 . ILE C 3 48 ? -67.487 -10.399 68.207 1.00 72.03 ? 48 ILE H CD1 1 ATOM 4061 N N . GLY C 3 49 ? -63.742 -9.170 71.799 1.00 73.94 ? 49 GLY H N 1 ATOM 4062 C CA . GLY C 3 49 ? -62.577 -9.581 72.562 1.00 73.29 ? 49 GLY H CA 1 ATOM 4063 C C . GLY C 3 49 ? -61.344 -9.650 71.689 1.00 72.03 ? 49 GLY H C 1 ATOM 4064 O O . GLY C 3 49 ? -61.406 -9.386 70.487 1.00 70.35 ? 49 GLY H O 1 ATOM 4065 N N . GLY C 3 50 ? -60.222 -9.999 72.306 1.00 73.05 ? 50 GLY H N 1 ATOM 4066 C CA . GLY C 3 50 ? -58.959 -10.157 71.595 1.00 73.93 ? 50 GLY H CA 1 ATOM 4067 C C . GLY C 3 50 ? -58.274 -11.443 72.006 1.00 74.56 ? 50 GLY H C 1 ATOM 4068 O O . GLY C 3 50 ? -58.547 -11.987 73.083 1.00 74.67 ? 50 GLY H O 1 ATOM 4069 N N . ILE C 3 51 ? -57.388 -11.936 71.145 1.00 74.36 ? 51 ILE H N 1 ATOM 4070 C CA . ILE C 3 51 ? -56.634 -13.153 71.436 1.00 74.38 ? 51 ILE H CA 1 ATOM 4071 C C . ILE C 3 51 ? -55.147 -12.957 71.139 1.00 75.07 ? 51 ILE H C 1 ATOM 4072 O O . ILE C 3 51 ? -54.773 -12.425 70.092 1.00 75.47 ? 51 ILE H O 1 ATOM 4073 C CB . ILE C 3 51 ? -57.193 -14.372 70.654 1.00 73.00 ? 51 ILE H CB 1 ATOM 4074 C CG1 . ILE C 3 51 ? -56.445 -15.650 71.046 1.00 73.67 ? 51 ILE H CG1 1 ATOM 4075 C CG2 . ILE C 3 51 ? -57.114 -14.138 69.155 1.00 72.21 ? 51 ILE H CG2 1 ATOM 4076 C CD1 . ILE C 3 51 ? -57.132 -16.922 70.607 1.00 74.19 ? 51 ILE H CD1 1 ATOM 4077 N N . ASN C 3 52 ? -54.307 -13.376 72.079 1.00 75.67 ? 52 ASN H N 1 ATOM 4078 C CA . ASN C 3 52 ? -52.862 -13.323 71.895 1.00 75.50 ? 52 ASN H CA 1 ATOM 4079 C C . ASN C 3 52 ? -52.444 -14.376 70.871 1.00 74.08 ? 52 ASN H C 1 ATOM 4080 O O . ASN C 3 52 ? -52.787 -15.552 71.004 1.00 72.60 ? 52 ASN H O 1 ATOM 4081 C CB . ASN C 3 52 ? -52.147 -13.544 73.231 1.00 76.03 ? 52 ASN H CB 1 ATOM 4082 C CG . ASN C 3 52 ? -50.671 -13.195 73.174 1.00 76.61 ? 52 ASN H CG 1 ATOM 4083 O OD1 . ASN C 3 52 ? -49.922 -13.733 72.358 1.00 77.31 ? 52 ASN H OD1 1 ATOM 4084 N ND2 . ASN C 3 52 ? -50.241 -12.300 74.056 1.00 77.11 ? 52 ASN H ND2 1 ATOM 4085 N N . THR C 3 53 ? -51.706 -13.946 69.853 1.00 74.70 ? 53 THR H N 1 ATOM 4086 C CA . THR C 3 53 ? -51.390 -14.799 68.704 1.00 76.10 ? 53 THR H CA 1 ATOM 4087 C C . THR C 3 53 ? -50.100 -15.609 68.874 1.00 77.10 ? 53 THR H C 1 ATOM 4088 O O . THR C 3 53 ? -49.693 -16.325 67.957 1.00 77.64 ? 53 THR H O 1 ATOM 4089 C CB . THR C 3 53 ? -51.295 -13.962 67.420 1.00 75.83 ? 53 THR H CB 1 ATOM 4090 O OG1 . THR C 3 53 ? -50.419 -12.850 67.640 1.00 76.70 ? 53 THR H OG1 1 ATOM 4091 C CG2 . THR C 3 53 ? -52.674 -13.452 67.017 1.00 75.06 ? 53 THR H CG2 1 ATOM 4092 N N . ILE C 3 54 ? -49.463 -15.496 70.038 1.00 77.66 ? 54 ILE H N 1 ATOM 4093 C CA . ILE C 3 54 ? -48.314 -16.335 70.377 1.00 78.15 ? 54 ILE H CA 1 ATOM 4094 C C . ILE C 3 54 ? -48.752 -17.486 71.284 1.00 79.75 ? 54 ILE H C 1 ATOM 4095 O O . ILE C 3 54 ? -48.545 -18.655 70.956 1.00 80.78 ? 54 ILE H O 1 ATOM 4096 C CB . ILE C 3 54 ? -47.205 -15.531 71.095 1.00 77.84 ? 54 ILE H CB 1 ATOM 4097 C CG1 . ILE C 3 54 ? -46.742 -14.353 70.234 1.00 77.70 ? 54 ILE H CG1 1 ATOM 4098 C CG2 . ILE C 3 54 ? -46.021 -16.432 71.415 1.00 77.41 ? 54 ILE H CG2 1 ATOM 4099 C CD1 . ILE C 3 54 ? -45.695 -13.483 70.899 1.00 77.46 ? 54 ILE H CD1 1 ATOM 4100 N N . ASN C 3 55 ? -49.368 -17.144 72.415 1.00 79.78 ? 55 ASN H N 1 ATOM 4101 C CA . ASN C 3 55 ? -49.691 -18.125 73.464 1.00 79.80 ? 55 ASN H CA 1 ATOM 4102 C C . ASN C 3 55 ? -51.170 -18.530 73.531 1.00 80.58 ? 55 ASN H C 1 ATOM 4103 O O . ASN C 3 55 ? -51.543 -19.388 74.331 1.00 81.24 ? 55 ASN H O 1 ATOM 4104 C CB . ASN C 3 55 ? -49.226 -17.608 74.835 1.00 80.39 ? 55 ASN H CB 1 ATOM 4105 C CG . ASN C 3 55 ? -49.784 -16.231 75.169 1.00 80.93 ? 55 ASN H CG 1 ATOM 4106 O OD1 . ASN C 3 55 ? -50.967 -15.959 74.965 1.00 80.94 ? 55 ASN H OD1 1 ATOM 4107 N ND2 . ASN C 3 55 ? -48.929 -15.357 75.689 1.00 80.84 ? 55 ASN H ND2 1 ATOM 4108 N N . GLY C 3 56 ? -52.007 -17.909 72.702 1.00 80.53 ? 56 GLY H N 1 ATOM 4109 C CA . GLY C 3 56 ? -53.423 -18.273 72.618 1.00 79.86 ? 56 GLY H CA 1 ATOM 4110 C C . GLY C 3 56 ? -54.282 -17.755 73.761 1.00 80.28 ? 56 GLY H C 1 ATOM 4111 O O . GLY C 3 56 ? -55.445 -18.143 73.890 1.00 81.17 ? 56 GLY H O 1 ATOM 4112 N N . GLY C 3 57 ? -53.717 -16.879 74.588 1.00 79.36 ? 57 GLY H N 1 ATOM 4113 C CA . GLY C 3 57 ? -54.454 -16.273 75.688 1.00 78.65 ? 57 GLY H CA 1 ATOM 4114 C C . GLY C 3 57 ? -55.431 -15.236 75.181 1.00 77.60 ? 57 GLY H C 1 ATOM 4115 O O . GLY C 3 57 ? -55.065 -14.377 74.381 1.00 77.10 ? 57 GLY H O 1 ATOM 4116 N N . SER C 3 58 ? -56.673 -15.310 75.654 1.00 78.17 ? 58 SER H N 1 ATOM 4117 C CA . SER C 3 58 ? -57.749 -14.453 75.155 1.00 78.65 ? 58 SER H CA 1 ATOM 4118 C C . SER C 3 58 ? -58.384 -13.614 76.261 1.00 78.18 ? 58 SER H C 1 ATOM 4119 O O . SER C 3 58 ? -58.367 -13.994 77.431 1.00 78.23 ? 58 SER H O 1 ATOM 4120 C CB . SER C 3 58 ? -58.820 -15.307 74.474 1.00 79.47 ? 58 SER H CB 1 ATOM 4121 O OG . SER C 3 58 ? -59.205 -16.392 75.302 1.00 80.00 ? 58 SER H OG 1 ATOM 4122 N N . SER C 3 59 ? -58.942 -12.472 75.869 1.00 78.25 ? 59 SER H N 1 ATOM 4123 C CA . SER C 3 59 ? -59.634 -11.569 76.789 1.00 78.20 ? 59 SER H CA 1 ATOM 4124 C C . SER C 3 59 ? -60.953 -11.109 76.169 1.00 77.87 ? 59 SER H C 1 ATOM 4125 O O . SER C 3 59 ? -60.991 -10.711 75.002 1.00 77.52 ? 59 SER H O 1 ATOM 4126 C CB . SER C 3 59 ? -58.755 -10.360 77.104 1.00 77.73 ? 59 SER H CB 1 ATOM 4127 O OG . SER C 3 59 ? -59.495 -9.337 77.749 1.00 77.83 ? 59 SER H OG 1 ATOM 4128 N N . TYR C 3 60 ? -62.023 -11.151 76.963 1.00 77.87 ? 60 TYR H N 1 ATOM 4129 C CA . TYR C 3 60 ? -63.376 -10.902 76.467 1.00 78.31 ? 60 TYR H CA 1 ATOM 4130 C C . TYR C 3 60 ? -64.076 -9.772 77.214 1.00 78.87 ? 60 TYR H C 1 ATOM 4131 O O . TYR C 3 60 ? -63.847 -9.556 78.406 1.00 78.91 ? 60 TYR H O 1 ATOM 4132 C CB . TYR C 3 60 ? -64.227 -12.163 76.606 1.00 77.50 ? 60 TYR H CB 1 ATOM 4133 C CG . TYR C 3 60 ? -63.632 -13.393 75.972 1.00 77.19 ? 60 TYR H CG 1 ATOM 4134 C CD1 . TYR C 3 60 ? -64.014 -13.795 74.699 1.00 77.01 ? 60 TYR H CD1 1 ATOM 4135 C CD2 . TYR C 3 60 ? -62.692 -14.162 76.651 1.00 77.35 ? 60 TYR H CD2 1 ATOM 4136 C CE1 . TYR C 3 60 ? -63.472 -14.929 74.115 1.00 77.47 ? 60 TYR H CE1 1 ATOM 4137 C CE2 . TYR C 3 60 ? -62.144 -15.298 76.077 1.00 77.52 ? 60 TYR H CE2 1 ATOM 4138 C CZ . TYR C 3 60 ? -62.537 -15.677 74.809 1.00 77.48 ? 60 TYR H CZ 1 ATOM 4139 O OH . TYR C 3 60 ? -61.999 -16.805 74.234 1.00 77.31 ? 60 TYR H OH 1 ATOM 4140 N N . LYS C 3 61 ? -64.944 -9.066 76.496 1.00 79.30 ? 61 LYS H N 1 ATOM 4141 C CA . LYS C 3 61 ? -65.882 -8.132 77.098 1.00 79.41 ? 61 LYS H CA 1 ATOM 4142 C C . LYS C 3 61 ? -66.906 -8.934 77.899 1.00 79.95 ? 61 LYS H C 1 ATOM 4143 O O . LYS C 3 61 ? -67.265 -10.044 77.508 1.00 80.62 ? 61 LYS H O 1 ATOM 4144 C CB . LYS C 3 61 ? -66.571 -7.321 76.001 1.00 79.59 ? 61 LYS H CB 1 ATOM 4145 C CG . LYS C 3 61 ? -67.454 -6.198 76.487 1.00 79.61 ? 61 LYS H CG 1 ATOM 4146 C CD . LYS C 3 61 ? -67.985 -5.392 75.314 1.00 79.58 ? 61 LYS H CD 1 ATOM 4147 C CE . LYS C 3 61 ? -69.091 -4.448 75.744 1.00 80.08 ? 61 LYS H CE 1 ATOM 4148 N NZ . LYS C 3 61 ? -69.539 -3.580 74.625 1.00 80.29 ? 61 LYS H NZ 1 ATOM 4149 N N . GLN C 3 62 ? -67.374 -8.369 79.012 1.00 80.24 ? 62 GLN H N 1 ATOM 4150 C CA . GLN C 3 62 ? -68.245 -9.089 79.956 1.00 80.37 ? 62 GLN H CA 1 ATOM 4151 C C . GLN C 3 62 ? -69.493 -9.675 79.291 1.00 81.00 ? 62 GLN H C 1 ATOM 4152 O O . GLN C 3 62 ? -69.941 -10.763 79.656 1.00 81.53 ? 62 GLN H O 1 ATOM 4153 C CB . GLN C 3 62 ? -68.671 -8.176 81.114 1.00 80.86 ? 62 GLN H CB 1 ATOM 4154 C CG . GLN C 3 62 ? -67.542 -7.775 82.070 1.00 81.28 ? 62 GLN H CG 1 ATOM 4155 C CD . GLN C 3 62 ? -66.809 -6.509 81.639 1.00 80.95 ? 62 GLN H CD 1 ATOM 4156 O OE1 . GLN C 3 62 ? -66.622 -6.259 80.445 1.00 80.56 ? 62 GLN H OE1 1 ATOM 4157 N NE2 . GLN C 3 62 ? -66.387 -5.708 82.614 1.00 80.28 ? 62 GLN H NE2 1 ATOM 4158 N N . SER C 3 63 ? -70.048 -8.950 78.322 1.00 81.31 ? 63 SER H N 1 ATOM 4159 C CA . SER C 3 63 ? -71.238 -9.393 77.594 1.00 81.45 ? 63 SER H CA 1 ATOM 4160 C C . SER C 3 63 ? -71.015 -10.713 76.855 1.00 82.08 ? 63 SER H C 1 ATOM 4161 O O . SER C 3 63 ? -71.875 -11.595 76.879 1.00 82.63 ? 63 SER H O 1 ATOM 4162 C CB . SER C 3 63 ? -71.670 -8.325 76.587 1.00 81.75 ? 63 SER H CB 1 ATOM 4163 O OG . SER C 3 63 ? -71.860 -7.071 77.219 1.00 82.14 ? 63 SER H OG 1 ATOM 4164 N N . PHE C 3 64 ? -69.857 -10.842 76.209 1.00 81.81 ? 64 PHE H N 1 ATOM 4165 C CA . PHE C 3 64 ? -69.574 -11.986 75.338 1.00 82.03 ? 64 PHE H CA 1 ATOM 4166 C C . PHE C 3 64 ? -68.799 -13.117 76.023 1.00 82.52 ? 64 PHE H C 1 ATOM 4167 O O . PHE C 3 64 ? -68.314 -14.031 75.355 1.00 82.82 ? 64 PHE H O 1 ATOM 4168 C CB . PHE C 3 64 ? -68.822 -11.515 74.089 1.00 81.22 ? 64 PHE H CB 1 ATOM 4169 C CG . PHE C 3 64 ? -69.580 -10.505 73.281 1.00 80.97 ? 64 PHE H CG 1 ATOM 4170 C CD1 . PHE C 3 64 ? -69.369 -9.146 73.467 1.00 81.10 ? 64 PHE H CD1 1 ATOM 4171 C CD2 . PHE C 3 64 ? -70.523 -10.913 72.349 1.00 81.15 ? 64 PHE H CD2 1 ATOM 4172 C CE1 . PHE C 3 64 ? -70.076 -8.206 72.729 1.00 81.08 ? 64 PHE H CE1 1 ATOM 4173 C CE2 . PHE C 3 64 ? -71.236 -9.979 71.607 1.00 81.39 ? 64 PHE H CE2 1 ATOM 4174 C CZ . PHE C 3 64 ? -71.011 -8.622 71.798 1.00 81.16 ? 64 PHE H CZ 1 ATOM 4175 N N . LYS C 3 65 ? -68.685 -13.062 77.348 1.00 82.92 ? 65 LYS H N 1 ATOM 4176 C CA . LYS C 3 65 ? -68.089 -14.159 78.108 1.00 83.35 ? 65 LYS H CA 1 ATOM 4177 C C . LYS C 3 65 ? -69.066 -15.337 78.118 1.00 84.66 ? 65 LYS H C 1 ATOM 4178 O O . LYS C 3 65 ? -70.233 -15.170 78.479 1.00 85.78 ? 65 LYS H O 1 ATOM 4179 C CB . LYS C 3 65 ? -67.769 -13.712 79.537 1.00 83.52 ? 65 LYS H CB 1 ATOM 4180 C CG . LYS C 3 65 ? -66.865 -14.667 80.306 1.00 83.48 ? 65 LYS H CG 1 ATOM 4181 C CD . LYS C 3 65 ? -66.538 -14.131 81.696 1.00 83.54 ? 65 LYS H CD 1 ATOM 4182 C CE . LYS C 3 65 ? -65.775 -15.158 82.527 1.00 83.66 ? 65 LYS H CE 1 ATOM 4183 N NZ . LYS C 3 65 ? -65.434 -14.648 83.890 1.00 83.49 ? 65 LYS H NZ 1 ATOM 4184 N N . ASP C 3 66 ? -68.584 -16.512 77.703 1.00 84.34 ? 66 ASP H N 1 ATOM 4185 C CA . ASP C 3 66 ? -69.408 -17.731 77.515 1.00 83.80 ? 66 ASP H CA 1 ATOM 4186 C C . ASP C 3 66 ? -70.122 -17.764 76.159 1.00 84.20 ? 66 ASP H C 1 ATOM 4187 O O . ASP C 3 66 ? -70.327 -18.840 75.595 1.00 84.98 ? 66 ASP H O 1 ATOM 4188 C CB . ASP C 3 66 ? -70.431 -17.941 78.648 1.00 84.62 ? 66 ASP H CB 1 ATOM 4189 C CG . ASP C 3 66 ? -69.779 -18.062 80.016 1.00 85.35 ? 66 ASP H CG 1 ATOM 4190 O OD1 . ASP C 3 66 ? -68.556 -17.830 80.123 1.00 85.87 ? 66 ASP H OD1 1 ATOM 4191 O OD2 . ASP C 3 66 ? -70.493 -18.395 80.987 1.00 85.55 ? 66 ASP H OD2 1 ATOM 4192 N N . LYS C 3 67 ? -70.512 -16.594 75.654 1.00 83.19 ? 67 LYS H N 1 ATOM 4193 C CA . LYS C 3 67 ? -71.099 -16.472 74.321 1.00 81.68 ? 67 LYS H CA 1 ATOM 4194 C C . LYS C 3 67 ? -70.042 -16.713 73.245 1.00 80.27 ? 67 LYS H C 1 ATOM 4195 O O . LYS C 3 67 ? -70.232 -17.549 72.364 1.00 80.15 ? 67 LYS H O 1 ATOM 4196 C CB . LYS C 3 67 ? -71.725 -15.080 74.147 1.00 82.22 ? 67 LYS H CB 1 ATOM 4197 C CG . LYS C 3 67 ? -72.298 -14.775 72.756 1.00 82.87 ? 67 LYS H CG 1 ATOM 4198 C CD . LYS C 3 67 ? -73.494 -15.650 72.404 1.00 83.24 ? 67 LYS H CD 1 ATOM 4199 C CE . LYS C 3 67 ? -74.750 -15.235 73.158 1.00 83.32 ? 67 LYS H CE 1 ATOM 4200 N NZ . LYS C 3 67 ? -75.912 -16.106 72.823 1.00 83.06 ? 67 LYS H NZ 1 ATOM 4201 N N . ALA C 3 68 ? -68.930 -15.982 73.333 1.00 79.56 ? 68 ALA H N 1 ATOM 4202 C CA . ALA C 3 68 ? -67.854 -16.053 72.338 1.00 79.07 ? 68 ALA H CA 1 ATOM 4203 C C . ALA C 3 68 ? -66.624 -16.791 72.874 1.00 78.33 ? 68 ALA H C 1 ATOM 4204 O O . ALA C 3 68 ? -66.305 -16.701 74.059 1.00 78.67 ? 68 ALA H O 1 ATOM 4205 C CB . ALA C 3 68 ? -67.466 -14.653 71.895 1.00 78.67 ? 68 ALA H CB 1 ATOM 4206 N N . THR C 3 69 ? -65.940 -17.515 71.989 1.00 78.10 ? 69 THR H N 1 ATOM 4207 C CA . THR C 3 69 ? -64.707 -18.234 72.330 1.00 78.00 ? 69 THR H CA 1 ATOM 4208 C C . THR C 3 69 ? -63.661 -18.063 71.222 1.00 78.01 ? 69 THR H C 1 ATOM 4209 O O . THR C 3 69 ? -63.813 -18.610 70.127 1.00 77.98 ? 69 THR H O 1 ATOM 4210 C CB . THR C 3 69 ? -64.973 -19.743 72.534 1.00 78.11 ? 69 THR H CB 1 ATOM 4211 O OG1 . THR C 3 69 ? -65.870 -19.932 73.633 1.00 78.23 ? 69 THR H OG1 1 ATOM 4212 C CG2 . THR C 3 69 ? -63.677 -20.490 72.811 1.00 78.01 ? 69 THR H CG2 1 ATOM 4213 N N . LEU C 3 70 ? -62.603 -17.307 71.515 1.00 77.48 ? 70 LEU H N 1 ATOM 4214 C CA . LEU C 3 70 ? -61.536 -17.057 70.547 1.00 76.55 ? 70 LEU H CA 1 ATOM 4215 C C . LEU C 3 70 ? -60.476 -18.147 70.607 1.00 75.73 ? 70 LEU H C 1 ATOM 4216 O O . LEU C 3 70 ? -60.068 -18.562 71.688 1.00 75.37 ? 70 LEU H O 1 ATOM 4217 C CB . LEU C 3 70 ? -60.882 -15.699 70.804 1.00 74.43 ? 70 LEU H CB 1 ATOM 4218 C CG . LEU C 3 70 ? -61.802 -14.477 70.779 1.00 73.43 ? 70 LEU H CG 1 ATOM 4219 C CD1 . LEU C 3 70 ? -60.980 -13.197 70.819 1.00 73.23 ? 70 LEU H CD1 1 ATOM 4220 C CD2 . LEU C 3 70 ? -62.705 -14.488 69.559 1.00 73.50 ? 70 LEU H CD2 1 ATOM 4221 N N . THR C 3 71 ? -60.045 -18.613 69.438 1.00 76.59 ? 71 THR H N 1 ATOM 4222 C CA . THR C 3 71 ? -58.962 -19.594 69.332 1.00 77.76 ? 71 THR H CA 1 ATOM 4223 C C . THR C 3 71 ? -58.081 -19.276 68.123 1.00 78.44 ? 71 THR H C 1 ATOM 4224 O O . THR C 3 71 ? -58.389 -18.374 67.340 1.00 78.12 ? 71 THR H O 1 ATOM 4225 C CB . THR C 3 71 ? -59.501 -21.042 69.220 1.00 77.60 ? 71 THR H CB 1 ATOM 4226 O OG1 . THR C 3 71 ? -60.386 -21.146 68.100 1.00 77.39 ? 71 THR H OG1 1 ATOM 4227 C CG2 . THR C 3 71 ? -60.240 -21.443 70.488 1.00 77.68 ? 71 THR H CG2 1 ATOM 4228 N N . VAL C 3 72 ? -56.988 -20.024 67.981 1.00 78.89 ? 72 VAL H N 1 ATOM 4229 C CA . VAL C 3 72 ? -55.960 -19.723 66.991 1.00 78.95 ? 72 VAL H CA 1 ATOM 4230 C C . VAL C 3 72 ? -55.252 -20.995 66.513 1.00 79.67 ? 72 VAL H C 1 ATOM 4231 O O . VAL C 3 72 ? -54.947 -21.882 67.311 1.00 79.90 ? 72 VAL H O 1 ATOM 4232 C CB . VAL C 3 72 ? -54.916 -18.736 67.586 1.00 78.43 ? 72 VAL H CB 1 ATOM 4233 C CG1 . VAL C 3 72 ? -53.536 -18.969 66.998 1.00 78.72 ? 72 VAL H CG1 1 ATOM 4234 C CG2 . VAL C 3 72 ? -55.362 -17.294 67.376 1.00 77.76 ? 72 VAL H CG2 1 ATOM 4235 N N . ASP C 3 73 ? -55.011 -21.078 65.206 1.00 80.41 ? 73 ASP H N 1 ATOM 4236 C CA . ASP C 3 73 ? -54.151 -22.111 64.628 1.00 80.45 ? 73 ASP H CA 1 ATOM 4237 C C . ASP C 3 73 ? -52.922 -21.430 64.024 1.00 80.93 ? 73 ASP H C 1 ATOM 4238 O O . ASP C 3 73 ? -52.974 -20.917 62.905 1.00 81.09 ? 73 ASP H O 1 ATOM 4239 C CB . ASP C 3 73 ? -54.908 -22.913 63.562 1.00 80.98 ? 73 ASP H CB 1 ATOM 4240 C CG . ASP C 3 73 ? -54.098 -24.090 63.017 1.00 81.39 ? 73 ASP H CG 1 ATOM 4241 O OD1 . ASP C 3 73 ? -53.052 -24.439 63.610 1.00 81.88 ? 73 ASP H OD1 1 ATOM 4242 O OD2 . ASP C 3 73 ? -54.518 -24.674 61.993 1.00 81.60 ? 73 ASP H OD2 1 ATOM 4243 N N . LYS C 3 74 ? -51.822 -21.432 64.775 1.00 81.18 ? 74 LYS H N 1 ATOM 4244 C CA . LYS C 3 74 ? -50.630 -20.654 64.419 1.00 80.95 ? 74 LYS H CA 1 ATOM 4245 C C . LYS C 3 74 ? -49.972 -21.111 63.116 1.00 80.51 ? 74 LYS H C 1 ATOM 4246 O O . LYS C 3 74 ? -49.470 -20.285 62.352 1.00 79.99 ? 74 LYS H O 1 ATOM 4247 C CB . LYS C 3 74 ? -49.603 -20.695 65.555 1.00 81.09 ? 74 LYS H CB 1 ATOM 4248 C CG . LYS C 3 74 ? -50.065 -20.012 66.839 1.00 81.13 ? 74 LYS H CG 1 ATOM 4249 C CD . LYS C 3 74 ? -48.892 -19.667 67.753 1.00 81.24 ? 74 LYS H CD 1 ATOM 4250 C CE . LYS C 3 74 ? -48.182 -20.917 68.271 1.00 81.55 ? 74 LYS H CE 1 ATOM 4251 N NZ . LYS C 3 74 ? -46.984 -20.592 69.096 1.00 81.25 ? 74 LYS H NZ 1 ATOM 4252 N N . SER C 3 75 ? -49.977 -22.419 62.869 1.00 80.68 ? 75 SER H N 1 ATOM 4253 C CA . SER C 3 75 ? -49.375 -22.980 61.658 1.00 80.93 ? 75 SER H CA 1 ATOM 4254 C C . SER C 3 75 ? -50.044 -22.437 60.395 1.00 81.20 ? 75 SER H C 1 ATOM 4255 O O . SER C 3 75 ? -49.363 -22.036 59.450 1.00 81.69 ? 75 SER H O 1 ATOM 4256 C CB . SER C 3 75 ? -49.456 -24.510 61.673 1.00 81.75 ? 75 SER H CB 1 ATOM 4257 O OG . SER C 3 75 ? -50.803 -24.952 61.675 1.00 82.47 ? 75 SER H OG 1 ATOM 4258 N N . SER C 3 76 ? -51.375 -22.418 60.394 1.00 80.78 ? 76 SER H N 1 ATOM 4259 C CA . SER C 3 76 ? -52.150 -21.929 59.250 1.00 80.13 ? 76 SER H CA 1 ATOM 4260 C C . SER C 3 76 ? -52.416 -20.420 59.311 1.00 78.97 ? 76 SER H C 1 ATOM 4261 O O . SER C 3 76 ? -53.061 -19.870 58.418 1.00 78.01 ? 76 SER H O 1 ATOM 4262 C CB . SER C 3 76 ? -53.484 -22.677 59.161 1.00 80.34 ? 76 SER H CB 1 ATOM 4263 O OG . SER C 3 76 ? -54.351 -22.310 60.223 1.00 80.29 ? 76 SER H OG 1 ATOM 4264 N N . SER C 3 77 ? -51.924 -19.760 60.359 1.00 79.14 ? 77 SER H N 1 ATOM 4265 C CA . SER C 3 77 ? -52.149 -18.327 60.561 1.00 79.30 ? 77 SER H CA 1 ATOM 4266 C C . SER C 3 77 ? -53.633 -17.989 60.437 1.00 78.72 ? 77 SER H C 1 ATOM 4267 O O . SER C 3 77 ? -54.024 -17.168 59.608 1.00 78.93 ? 77 SER H O 1 ATOM 4268 C CB . SER C 3 77 ? -51.322 -17.504 59.566 1.00 79.66 ? 77 SER H CB 1 ATOM 4269 O OG . SER C 3 77 ? -49.937 -17.762 59.717 1.00 79.86 ? 77 SER H OG 1 ATOM 4270 N N . THR C 3 78 ? -54.449 -18.642 61.260 1.00 78.33 ? 78 THR H N 1 ATOM 4271 C CA . THR C 3 78 ? -55.901 -18.484 61.210 1.00 78.39 ? 78 THR H CA 1 ATOM 4272 C C . THR C 3 78 ? -56.476 -18.262 62.606 1.00 77.77 ? 78 THR H C 1 ATOM 4273 O O . THR C 3 78 ? -56.078 -18.926 63.560 1.00 77.63 ? 78 THR H O 1 ATOM 4274 C CB . THR C 3 78 ? -56.573 -19.726 60.590 1.00 78.25 ? 78 THR H CB 1 ATOM 4275 O OG1 . THR C 3 78 ? -56.045 -19.958 59.280 1.00 78.21 ? 78 THR H OG1 1 ATOM 4276 C CG2 . THR C 3 78 ? -58.077 -19.535 60.492 1.00 78.66 ? 78 THR H CG2 1 ATOM 4277 N N . ALA C 3 79 ? -57.413 -17.323 62.712 1.00 77.93 ? 79 ALA H N 1 ATOM 4278 C CA . ALA C 3 79 ? -58.112 -17.051 63.967 1.00 78.52 ? 79 ALA H CA 1 ATOM 4279 C C . ALA C 3 79 ? -59.561 -17.512 63.850 1.00 79.40 ? 79 ALA H C 1 ATOM 4280 O O . ALA C 3 79 ? -60.231 -17.221 62.858 1.00 79.40 ? 79 ALA H O 1 ATOM 4281 C CB . ALA C 3 79 ? -58.055 -15.572 64.290 1.00 77.59 ? 79 ALA H CB 1 ATOM 4282 N N . TYR C 3 80 ? -60.037 -18.231 64.864 1.00 79.55 ? 80 TYR H N 1 ATOM 4283 C CA . TYR C 3 80 ? -61.412 -18.719 64.886 1.00 79.26 ? 80 TYR H CA 1 ATOM 4284 C C . TYR C 3 80 ? -62.172 -18.117 66.058 1.00 78.95 ? 80 TYR H C 1 ATOM 4285 O O . TYR C 3 80 ? -61.684 -18.132 67.185 1.00 78.68 ? 80 TYR H O 1 ATOM 4286 C CB . TYR C 3 80 ? -61.436 -20.241 65.016 1.00 79.72 ? 80 TYR H CB 1 ATOM 4287 C CG . TYR C 3 80 ? -60.685 -20.975 63.935 1.00 79.65 ? 80 TYR H CG 1 ATOM 4288 C CD1 . TYR C 3 80 ? -61.256 -21.183 62.685 1.00 79.86 ? 80 TYR H CD1 1 ATOM 4289 C CD2 . TYR C 3 80 ? -59.411 -21.480 64.168 1.00 79.75 ? 80 TYR H CD2 1 ATOM 4290 C CE1 . TYR C 3 80 ? -60.573 -21.869 61.687 1.00 79.97 ? 80 TYR H CE1 1 ATOM 4291 C CE2 . TYR C 3 80 ? -58.718 -22.168 63.179 1.00 79.93 ? 80 TYR H CE2 1 ATOM 4292 C CZ . TYR C 3 80 ? -59.303 -22.359 61.939 1.00 79.95 ? 80 TYR H CZ 1 ATOM 4293 O OH . TYR C 3 80 ? -58.620 -23.038 60.954 1.00 79.71 ? 80 TYR H OH 1 ATOM 4294 N N . MET C 3 81 ? -63.360 -17.583 65.787 1.00 79.38 ? 81 MET H N 1 ATOM 4295 C CA . MET C 3 81 ? -64.297 -17.202 66.845 1.00 79.53 ? 81 MET H CA 1 ATOM 4296 C C . MET C 3 81 ? -65.519 -18.104 66.770 1.00 79.25 ? 81 MET H C 1 ATOM 4297 O O . MET C 3 81 ? -66.199 -18.148 65.744 1.00 79.13 ? 81 MET H O 1 ATOM 4298 C CB . MET C 3 81 ? -64.730 -15.739 66.706 1.00 79.20 ? 81 MET H CB 1 ATOM 4299 C CG . MET C 3 81 ? -65.778 -15.315 67.736 1.00 79.37 ? 81 MET H CG 1 ATOM 4300 S SD . MET C 3 81 ? -66.099 -13.541 67.764 1.00 80.08 ? 81 MET H SD 1 ATOM 4301 C CE . MET C 3 81 ? -66.785 -13.296 66.125 1.00 79.59 ? 81 MET H CE 1 ATOM 4302 N N . GLU C 3 82 ? -65.796 -18.820 67.857 1.00 79.44 ? 82 GLU H N 1 ATOM 4303 C CA . GLU C 3 82 ? -67.000 -19.637 67.949 1.00 79.12 ? 82 GLU H CA 1 ATOM 4304 C C . GLU C 3 82 ? -68.058 -18.914 68.772 1.00 77.97 ? 82 GLU H C 1 ATOM 4305 O O . GLU C 3 82 ? -67.769 -18.420 69.859 1.00 77.22 ? 82 GLU H O 1 ATOM 4306 C CB . GLU C 3 82 ? -66.687 -20.991 68.579 1.00 78.95 ? 82 GLU H CB 1 ATOM 4307 C CG . GLU C 3 82 ? -67.868 -21.951 68.572 1.00 79.72 ? 82 GLU H CG 1 ATOM 4308 C CD . GLU C 3 82 ? -67.453 -23.397 68.761 1.00 80.88 ? 82 GLU H CD 1 ATOM 4309 O OE1 . GLU C 3 82 ? -68.075 -24.284 68.133 1.00 81.54 ? 82 GLU H OE1 1 ATOM 4310 O OE2 . GLU C 3 82 ? -66.502 -23.646 69.534 1.00 82.14 ? 82 GLU H OE2 1 ATOM 4311 N N . LEU C 3 83 ? -69.276 -18.844 68.236 1.00 78.15 ? 83 LEU H N 1 ATOM 4312 C CA . LEU C 3 83 ? -70.430 -18.305 68.959 1.00 78.72 ? 83 LEU H CA 1 ATOM 4313 C C . LEU C 3 83 ? -71.406 -19.442 69.256 1.00 78.98 ? 83 LEU H C 1 ATOM 4314 O O . LEU C 3 83 ? -71.691 -20.254 68.377 1.00 79.38 ? 83 LEU H O 1 ATOM 4315 C CB . LEU C 3 83 ? -71.127 -17.228 68.124 1.00 78.86 ? 83 LEU H CB 1 ATOM 4316 C CG . LEU C 3 83 ? -70.284 -16.005 67.749 1.00 79.22 ? 83 LEU H CG 1 ATOM 4317 C CD1 . LEU C 3 83 ? -71.031 -15.121 66.762 1.00 79.03 ? 83 LEU H CD1 1 ATOM 4318 C CD2 . LEU C 3 83 ? -69.894 -15.214 68.990 1.00 79.32 ? 83 LEU H CD2 1 ATOM 4319 N N . ASN C 3 84 ? -71.912 -19.502 70.487 1.00 78.70 ? 84 ASN H N 1 ATOM 4320 C CA . ASN C 3 84 ? -72.845 -20.564 70.884 1.00 78.57 ? 84 ASN H CA 1 ATOM 4321 C C . ASN C 3 84 ? -74.101 -20.034 71.576 1.00 77.67 ? 84 ASN H C 1 ATOM 4322 O O . ASN C 3 84 ? -74.159 -18.868 71.966 1.00 76.94 ? 84 ASN H O 1 ATOM 4323 C CB . ASN C 3 84 ? -72.141 -21.609 71.762 1.00 79.95 ? 84 ASN H CB 1 ATOM 4324 C CG . ASN C 3 84 ? -71.521 -21.014 73.019 1.00 81.47 ? 84 ASN H CG 1 ATOM 4325 O OD1 . ASN C 3 84 ? -72.063 -20.088 73.621 1.00 82.20 ? 84 ASN H OD1 1 ATOM 4326 N ND2 . ASN C 3 84 ? -70.384 -21.564 73.430 1.00 81.99 ? 84 ASN H ND2 1 ATOM 4327 N N . SER C 3 85 ? -75.100 -20.907 71.714 1.00 77.71 ? 85 SER H N 1 ATOM 4328 C CA . SER C 3 85 ? -76.402 -20.547 72.288 1.00 78.14 ? 85 SER H CA 1 ATOM 4329 C C . SER C 3 85 ? -77.019 -19.354 71.556 1.00 78.11 ? 85 SER H C 1 ATOM 4330 O O . SER C 3 85 ? -77.559 -18.438 72.179 1.00 78.35 ? 85 SER H O 1 ATOM 4331 C CB . SER C 3 85 ? -76.269 -20.249 73.786 1.00 78.97 ? 85 SER H CB 1 ATOM 4332 O OG . SER C 3 85 ? -75.518 -21.255 74.445 1.00 79.48 ? 85 SER H OG 1 ATOM 4333 N N . LEU C 3 86 ? -76.946 -19.389 70.228 1.00 77.81 ? 86 LEU H N 1 ATOM 4334 C CA . LEU C 3 86 ? -77.275 -18.230 69.401 1.00 77.57 ? 86 LEU H CA 1 ATOM 4335 C C . LEU C 3 86 ? -78.751 -17.854 69.486 1.00 76.99 ? 86 LEU H C 1 ATOM 4336 O O . LEU C 3 86 ? -79.627 -18.706 69.343 1.00 76.52 ? 86 LEU H O 1 ATOM 4337 C CB . LEU C 3 86 ? -76.886 -18.489 67.939 1.00 77.40 ? 86 LEU H CB 1 ATOM 4338 C CG . LEU C 3 86 ? -75.382 -18.474 67.656 1.00 76.99 ? 86 LEU H CG 1 ATOM 4339 C CD1 . LEU C 3 86 ? -75.055 -19.204 66.360 1.00 76.41 ? 86 LEU H CD1 1 ATOM 4340 C CD2 . LEU C 3 86 ? -74.862 -17.041 67.616 1.00 77.28 ? 86 LEU H CD2 1 ATOM 4341 N N . THR C 3 87 ? -79.008 -16.572 69.733 1.00 77.11 ? 87 THR H N 1 ATOM 4342 C CA . THR C 3 87 ? -80.355 -16.014 69.702 1.00 77.47 ? 87 THR H CA 1 ATOM 4343 C C . THR C 3 87 ? -80.456 -15.031 68.538 1.00 77.04 ? 87 THR H C 1 ATOM 4344 O O . THR C 3 87 ? -79.482 -14.816 67.818 1.00 77.06 ? 87 THR H O 1 ATOM 4345 C CB . THR C 3 87 ? -80.699 -15.297 71.029 1.00 77.31 ? 87 THR H CB 1 ATOM 4346 O OG1 . THR C 3 87 ? -79.740 -14.263 71.289 1.00 76.96 ? 87 THR H OG1 1 ATOM 4347 C CG2 . THR C 3 87 ? -80.701 -16.286 72.188 1.00 77.46 ? 87 THR H CG2 1 ATOM 4348 N N . SER C 3 88 ? -81.636 -14.446 68.352 1.00 77.62 ? 88 SER H N 1 ATOM 4349 C CA . SER C 3 88 ? -81.854 -13.451 67.299 1.00 78.84 ? 88 SER H CA 1 ATOM 4350 C C . SER C 3 88 ? -81.007 -12.192 67.511 1.00 79.22 ? 88 SER H C 1 ATOM 4351 O O . SER C 3 88 ? -80.646 -11.509 66.550 1.00 79.23 ? 88 SER H O 1 ATOM 4352 C CB . SER C 3 88 ? -83.335 -13.070 67.230 1.00 80.19 ? 88 SER H CB 1 ATOM 4353 O OG . SER C 3 88 ? -83.564 -12.078 66.244 1.00 81.09 ? 88 SER H OG 1 ATOM 4354 N N . GLU C 3 89 ? -80.694 -11.899 68.772 1.00 79.58 ? 89 GLU H N 1 ATOM 4355 C CA . GLU C 3 89 ? -79.854 -10.753 69.132 1.00 79.80 ? 89 GLU H CA 1 ATOM 4356 C C . GLU C 3 89 ? -78.419 -10.900 68.616 1.00 80.19 ? 89 GLU H C 1 ATOM 4357 O O . GLU C 3 89 ? -77.706 -9.906 68.461 1.00 80.45 ? 89 GLU H O 1 ATOM 4358 C CB . GLU C 3 89 ? -79.836 -10.572 70.655 1.00 79.84 ? 89 GLU H CB 1 ATOM 4359 C CG . GLU C 3 89 ? -81.201 -10.242 71.263 1.00 80.27 ? 89 GLU H CG 1 ATOM 4360 C CD . GLU C 3 89 ? -81.301 -10.602 72.738 0.50 80.26 ? 89 GLU H CD 1 ATOM 4361 O OE1 . GLU C 3 89 ? -80.271 -10.540 73.446 0.50 80.40 ? 89 GLU H OE1 1 ATOM 4362 O OE2 . GLU C 3 89 ? -82.416 -10.943 73.190 0.50 80.11 ? 89 GLU H OE2 1 ATOM 4363 N N . ASP C 3 90 ? -78.005 -12.140 68.351 1.00 80.08 ? 90 ASP H N 1 ATOM 4364 C CA . ASP C 3 90 ? -76.657 -12.427 67.854 1.00 79.95 ? 90 ASP H CA 1 ATOM 4365 C C . ASP C 3 90 ? -76.530 -12.275 66.330 1.00 79.40 ? 90 ASP H C 1 ATOM 4366 O O . ASP C 3 90 ? -75.435 -12.412 65.783 1.00 78.76 ? 90 ASP H O 1 ATOM 4367 C CB . ASP C 3 90 ? -76.234 -13.838 68.276 1.00 81.23 ? 90 ASP H CB 1 ATOM 4368 C CG . ASP C 3 90 ? -76.254 -14.028 69.788 1.00 82.73 ? 90 ASP H CG 1 ATOM 4369 O OD1 . ASP C 3 90 ? -75.565 -13.265 70.500 1.00 83.18 ? 90 ASP H OD1 1 ATOM 4370 O OD2 . ASP C 3 90 ? -76.957 -14.943 70.264 1.00 83.29 ? 90 ASP H OD2 1 ATOM 4371 N N . SER C 3 91 ? -77.643 -11.995 65.650 1.00 79.22 ? 91 SER H N 1 ATOM 4372 C CA . SER C 3 91 ? -77.620 -11.742 64.208 1.00 78.79 ? 91 SER H CA 1 ATOM 4373 C C . SER C 3 91 ? -76.963 -10.396 63.913 1.00 78.52 ? 91 SER H C 1 ATOM 4374 O O . SER C 3 91 ? -77.478 -9.346 64.306 1.00 78.26 ? 91 SER H O 1 ATOM 4375 C CB . SER C 3 91 ? -79.036 -11.761 63.628 1.00 79.21 ? 91 SER H CB 1 ATOM 4376 O OG . SER C 3 91 ? -79.627 -13.042 63.760 1.00 79.90 ? 91 SER H OG 1 ATOM 4377 N N . ALA C 3 92 ? -75.825 -10.437 63.224 1.00 78.08 ? 92 ALA H N 1 ATOM 4378 C CA . ALA C 3 92 ? -75.067 -9.228 62.899 1.00 77.04 ? 92 ALA H CA 1 ATOM 4379 C C . ALA C 3 92 ? -73.887 -9.564 61.994 1.00 76.05 ? 92 ALA H C 1 ATOM 4380 O O . ALA C 3 92 ? -73.699 -10.722 61.616 1.00 76.19 ? 92 ALA H O 1 ATOM 4381 C CB . ALA C 3 92 ? -74.575 -8.557 64.176 1.00 76.76 ? 92 ALA H CB 1 ATOM 4382 N N . VAL C 3 93 ? -73.103 -8.547 61.643 1.00 75.39 ? 93 VAL H N 1 ATOM 4383 C CA . VAL C 3 93 ? -71.857 -8.749 60.904 1.00 75.61 ? 93 VAL H CA 1 ATOM 4384 C C . VAL C 3 93 ? -70.685 -8.770 61.881 1.00 75.92 ? 93 VAL H C 1 ATOM 4385 O O . VAL C 3 93 ? -70.549 -7.865 62.705 1.00 76.40 ? 93 VAL H O 1 ATOM 4386 C CB . VAL C 3 93 ? -71.626 -7.638 59.864 1.00 74.37 ? 93 VAL H CB 1 ATOM 4387 C CG1 . VAL C 3 93 ? -70.302 -7.852 59.140 1.00 73.70 ? 93 VAL H CG1 1 ATOM 4388 C CG2 . VAL C 3 93 ? -72.781 -7.591 58.872 1.00 73.84 ? 93 VAL H CG2 1 ATOM 4389 N N . TYR C 3 94 ? -69.846 -9.802 61.788 1.00 75.72 ? 94 TYR H N 1 ATOM 4390 C CA . TYR C 3 94 ? -68.691 -9.957 62.682 1.00 75.58 ? 94 TYR H CA 1 ATOM 4391 C C . TYR C 3 94 ? -67.371 -9.772 61.933 1.00 75.57 ? 94 TYR H C 1 ATOM 4392 O O . TYR C 3 94 ? -67.167 -10.363 60.871 1.00 75.79 ? 94 TYR H O 1 ATOM 4393 C CB . TYR C 3 94 ? -68.726 -11.330 63.347 1.00 75.49 ? 94 TYR H CB 1 ATOM 4394 C CG . TYR C 3 94 ? -69.892 -11.512 64.291 1.00 75.63 ? 94 TYR H CG 1 ATOM 4395 C CD1 . TYR C 3 94 ? -69.760 -11.239 65.649 1.00 75.64 ? 94 TYR H CD1 1 ATOM 4396 C CD2 . TYR C 3 94 ? -71.128 -11.950 63.829 1.00 75.84 ? 94 TYR H CD2 1 ATOM 4397 C CE1 . TYR C 3 94 ? -70.824 -11.402 66.525 1.00 75.33 ? 94 TYR H CE1 1 ATOM 4398 C CE2 . TYR C 3 94 ? -72.203 -12.116 64.699 1.00 75.76 ? 94 TYR H CE2 1 ATOM 4399 C CZ . TYR C 3 94 ? -72.042 -11.839 66.045 1.00 75.46 ? 94 TYR H CZ 1 ATOM 4400 O OH . TYR C 3 94 ? -73.100 -12.002 66.910 1.00 75.60 ? 94 TYR H OH 1 ATOM 4401 N N . TYR C 3 95 ? -66.478 -8.957 62.498 1.00 75.48 ? 95 TYR H N 1 ATOM 4402 C CA . TYR C 3 95 ? -65.196 -8.629 61.868 1.00 75.33 ? 95 TYR H CA 1 ATOM 4403 C C . TYR C 3 95 ? -64.019 -9.103 62.707 1.00 75.57 ? 95 TYR H C 1 ATOM 4404 O O . TYR C 3 95 ? -63.988 -8.862 63.909 1.00 75.95 ? 95 TYR H O 1 ATOM 4405 C CB . TYR C 3 95 ? -65.055 -7.114 61.716 1.00 74.18 ? 95 TYR H CB 1 ATOM 4406 C CG . TYR C 3 95 ? -66.033 -6.463 60.775 1.00 73.81 ? 95 TYR H CG 1 ATOM 4407 C CD1 . TYR C 3 95 ? -65.744 -6.337 59.421 1.00 73.86 ? 95 TYR H CD1 1 ATOM 4408 C CD2 . TYR C 3 95 ? -67.229 -5.937 61.242 1.00 73.78 ? 95 TYR H CD2 1 ATOM 4409 C CE1 . TYR C 3 95 ? -66.630 -5.727 58.553 1.00 73.86 ? 95 TYR H CE1 1 ATOM 4410 C CE2 . TYR C 3 95 ? -68.125 -5.323 60.382 1.00 74.06 ? 95 TYR H CE2 1 ATOM 4411 C CZ . TYR C 3 95 ? -67.820 -5.221 59.039 1.00 74.01 ? 95 TYR H CZ 1 ATOM 4412 O OH . TYR C 3 95 ? -68.708 -4.615 58.184 1.00 74.15 ? 95 TYR H OH 1 ATOM 4413 N N . CYS C 3 96 ? -63.047 -9.761 62.073 1.00 76.00 ? 96 CYS H N 1 ATOM 4414 C CA . CYS C 3 96 ? -61.712 -9.901 62.657 1.00 76.45 ? 96 CYS H CA 1 ATOM 4415 C C . CYS C 3 96 ? -60.907 -8.660 62.271 1.00 75.72 ? 96 CYS H C 1 ATOM 4416 O O . CYS C 3 96 ? -61.098 -8.106 61.191 1.00 74.68 ? 96 CYS H O 1 ATOM 4417 C CB . CYS C 3 96 ? -61.003 -11.189 62.191 1.00 78.22 ? 96 CYS H CB 1 ATOM 4418 S SG . CYS C 3 96 ? -60.685 -11.310 60.408 1.00 81.89 ? 96 CYS H SG 1 ATOM 4419 N N . ALA C 3 97 ? -60.037 -8.208 63.169 1.00 76.47 ? 97 ALA H N 1 ATOM 4420 C CA . ALA C 3 97 ? -59.166 -7.064 62.895 1.00 76.98 ? 97 ALA H CA 1 ATOM 4421 C C . ALA C 3 97 ? -57.836 -7.248 63.604 1.00 77.70 ? 97 ALA H C 1 ATOM 4422 O O . ALA C 3 97 ? -57.764 -7.945 64.614 1.00 79.17 ? 97 ALA H O 1 ATOM 4423 C CB . ALA C 3 97 ? -59.826 -5.774 63.337 1.00 77.25 ? 97 ALA H CB 1 ATOM 4424 N N . THR C 3 98 ? -56.786 -6.622 63.078 1.00 77.12 ? 98 THR H N 1 ATOM 4425 C CA . THR C 3 98 ? -55.448 -6.781 63.641 1.00 77.52 ? 98 THR H CA 1 ATOM 4426 C C . THR C 3 98 ? -54.576 -5.528 63.481 1.00 77.57 ? 98 THR H C 1 ATOM 4427 O O . THR C 3 98 ? -54.967 -4.560 62.822 1.00 77.39 ? 98 THR H O 1 ATOM 4428 C CB . THR C 3 98 ? -54.730 -8.001 63.018 1.00 78.39 ? 98 THR H CB 1 ATOM 4429 O OG1 . THR C 3 98 ? -53.640 -8.397 63.858 1.00 79.39 ? 98 THR H OG1 1 ATOM 4430 C CG2 . THR C 3 98 ? -54.211 -7.684 61.617 1.00 77.90 ? 98 THR H CG2 1 ATOM 4431 N N . LYS C 3 99 ? -53.393 -5.573 64.091 1.00 77.34 ? 99 LYS H N 1 ATOM 4432 C CA . LYS C 3 99 ? -52.472 -4.434 64.151 1.00 77.52 ? 99 LYS H CA 1 ATOM 4433 C C . LYS C 3 99 ? -53.176 -3.162 64.630 1.00 77.58 ? 99 LYS H C 1 ATOM 4434 O O . LYS C 3 99 ? -53.240 -2.161 63.912 1.00 77.62 ? 99 LYS H O 1 ATOM 4435 C CB . LYS C 3 99 ? -51.783 -4.202 62.800 1.00 78.01 ? 99 LYS H CB 1 ATOM 4436 C CG . LYS C 3 99 ? -50.608 -3.231 62.884 1.00 78.05 ? 99 LYS H CG 1 ATOM 4437 C CD . LYS C 3 99 ? -49.773 -3.213 61.619 1.00 78.06 ? 99 LYS H CD 1 ATOM 4438 C CE . LYS C 3 99 ? -48.519 -2.370 61.818 1.00 78.30 ? 99 LYS H CE 1 ATOM 4439 N NZ . LYS C 3 99 ? -47.607 -2.415 60.642 1.00 78.76 ? 99 LYS H NZ 1 ATOM 4440 N N . GLY C 3 100 ? -53.705 -3.217 65.849 1.00 77.05 ? 100 GLY H N 1 ATOM 4441 C CA . GLY C 3 100 ? -54.423 -2.089 66.430 1.00 76.29 ? 100 GLY H CA 1 ATOM 4442 C C . GLY C 3 100 ? -55.522 -1.575 65.521 1.00 75.65 ? 100 GLY H C 1 ATOM 4443 O O . GLY C 3 100 ? -55.672 -0.370 65.342 1.00 75.63 ? 100 GLY H O 1 ATOM 4444 N N . PHE C 3 101 ? -56.283 -2.500 64.939 1.00 75.50 ? 101 PHE H N 1 ATOM 4445 C CA . PHE C 3 101 ? -57.403 -2.167 64.051 1.00 75.17 ? 101 PHE H CA 1 ATOM 4446 C C . PHE C 3 101 ? -56.973 -1.387 62.799 1.00 74.85 ? 101 PHE H C 1 ATOM 4447 O O . PHE C 3 101 ? -57.688 -0.499 62.338 1.00 74.51 ? 101 PHE H O 1 ATOM 4448 C CB . PHE C 3 101 ? -58.485 -1.397 64.819 1.00 73.92 ? 101 PHE H CB 1 ATOM 4449 C CG . PHE C 3 101 ? -58.897 -2.055 66.103 1.00 73.67 ? 101 PHE H CG 1 ATOM 4450 C CD1 . PHE C 3 101 ? -59.877 -3.037 66.109 1.00 73.63 ? 101 PHE H CD1 1 ATOM 4451 C CD2 . PHE C 3 101 ? -58.302 -1.700 67.304 1.00 73.69 ? 101 PHE H CD2 1 ATOM 4452 C CE1 . PHE C 3 101 ? -60.259 -3.653 67.291 1.00 73.61 ? 101 PHE H CE1 1 ATOM 4453 C CE2 . PHE C 3 101 ? -58.679 -2.309 68.487 1.00 73.97 ? 101 PHE H CE2 1 ATOM 4454 C CZ . PHE C 3 101 ? -59.660 -3.291 68.479 1.00 73.97 ? 101 PHE H CZ 1 ATOM 4455 N N . ALA C 3 102 ? -55.806 -1.726 62.257 1.00 74.98 ? 102 ALA H N 1 ATOM 4456 C CA . ALA C 3 102 ? -55.335 -1.130 61.002 1.00 75.23 ? 102 ALA H CA 1 ATOM 4457 C C . ALA C 3 102 ? -55.802 -1.956 59.801 1.00 74.54 ? 102 ALA H C 1 ATOM 4458 O O . ALA C 3 102 ? -56.047 -1.412 58.727 1.00 73.02 ? 102 ALA H O 1 ATOM 4459 C CB . ALA C 3 102 ? -53.818 -1.011 61.005 1.00 74.74 ? 102 ALA H CB 1 ATOM 4460 N N . TYR C 3 103 ? -55.915 -3.269 59.994 1.00 75.76 ? 103 TYR H N 1 ATOM 4461 C CA . TYR C 3 103 ? -56.390 -4.180 58.955 1.00 76.35 ? 103 TYR H CA 1 ATOM 4462 C C . TYR C 3 103 ? -57.606 -4.954 59.449 1.00 75.91 ? 103 TYR H C 1 ATOM 4463 O O . TYR C 3 103 ? -57.557 -5.586 60.503 1.00 76.43 ? 103 TYR H O 1 ATOM 4464 C CB . TYR C 3 103 ? -55.285 -5.164 58.564 1.00 79.26 ? 103 TYR H CB 1 ATOM 4465 C CG . TYR C 3 103 ? -53.980 -4.497 58.202 1.00 79.73 ? 103 TYR H CG 1 ATOM 4466 C CD1 . TYR C 3 103 ? -52.825 -4.734 58.942 1.00 79.92 ? 103 TYR H CD1 1 ATOM 4467 C CD2 . TYR C 3 103 ? -53.903 -3.616 57.128 1.00 79.99 ? 103 TYR H CD2 1 ATOM 4468 C CE1 . TYR C 3 103 ? -51.624 -4.118 58.615 1.00 79.60 ? 103 TYR H CE1 1 ATOM 4469 C CE2 . TYR C 3 103 ? -52.709 -2.995 56.793 1.00 79.64 ? 103 TYR H CE2 1 ATOM 4470 C CZ . TYR C 3 103 ? -51.573 -3.251 57.542 1.00 79.57 ? 103 TYR H CZ 1 ATOM 4471 O OH . TYR C 3 103 ? -50.382 -2.640 57.220 1.00 80.11 ? 103 TYR H OH 1 ATOM 4472 N N . TRP C 3 104 ? -58.692 -4.896 58.683 1.00 75.14 ? 104 TRP H N 1 ATOM 4473 C CA . TRP C 3 104 ? -59.931 -5.590 59.018 1.00 74.75 ? 104 TRP H CA 1 ATOM 4474 C C . TRP C 3 104 ? -60.218 -6.677 57.995 1.00 74.06 ? 104 TRP H C 1 ATOM 4475 O O . TRP C 3 104 ? -59.700 -6.641 56.879 1.00 74.84 ? 104 TRP H O 1 ATOM 4476 C CB . TRP C 3 104 ? -61.099 -4.605 59.023 1.00 74.09 ? 104 TRP H CB 1 ATOM 4477 C CG . TRP C 3 104 ? -61.018 -3.546 60.075 1.00 74.03 ? 104 TRP H CG 1 ATOM 4478 C CD1 . TRP C 3 104 ? -60.112 -2.528 60.149 1.00 74.14 ? 104 TRP H CD1 1 ATOM 4479 C CD2 . TRP C 3 104 ? -61.900 -3.380 61.188 1.00 73.69 ? 104 TRP H CD2 1 ATOM 4480 N NE1 . TRP C 3 104 ? -60.368 -1.747 61.251 1.00 73.97 ? 104 TRP H NE1 1 ATOM 4481 C CE2 . TRP C 3 104 ? -61.463 -2.248 61.904 1.00 73.82 ? 104 TRP H CE2 1 ATOM 4482 C CE3 . TRP C 3 104 ? -63.016 -4.082 61.654 1.00 74.03 ? 104 TRP H CE3 1 ATOM 4483 C CZ2 . TRP C 3 104 ? -62.102 -1.802 63.061 1.00 74.02 ? 104 TRP H CZ2 1 ATOM 4484 C CZ3 . TRP C 3 104 ? -63.651 -3.638 62.804 1.00 73.98 ? 104 TRP H CZ3 1 ATOM 4485 C CH2 . TRP C 3 104 ? -63.191 -2.510 63.494 1.00 73.95 ? 104 TRP H CH2 1 ATOM 4486 N N . GLY C 3 105 ? -61.050 -7.640 58.377 1.00 73.91 ? 105 GLY H N 1 ATOM 4487 C CA . GLY C 3 105 ? -61.610 -8.603 57.426 1.00 74.96 ? 105 GLY H CA 1 ATOM 4488 C C . GLY C 3 105 ? -62.824 -8.016 56.723 1.00 75.01 ? 105 GLY H C 1 ATOM 4489 O O . GLY C 3 105 ? -63.300 -6.941 57.091 1.00 75.42 ? 105 GLY H O 1 ATOM 4490 N N . GLN C 3 106 ? -63.335 -8.718 55.714 1.00 74.76 ? 106 GLN H N 1 ATOM 4491 C CA . GLN C 3 106 ? -64.454 -8.200 54.916 1.00 75.63 ? 106 GLN H CA 1 ATOM 4492 C C . GLN C 3 106 ? -65.794 -8.243 55.660 1.00 76.14 ? 106 GLN H C 1 ATOM 4493 O O . GLN C 3 106 ? -66.768 -7.630 55.223 1.00 76.73 ? 106 GLN H O 1 ATOM 4494 C CB . GLN C 3 106 ? -64.561 -8.927 53.564 1.00 76.18 ? 106 GLN H CB 1 ATOM 4495 C CG . GLN C 3 106 ? -65.182 -10.330 53.601 1.00 77.18 ? 106 GLN H CG 1 ATOM 4496 C CD . GLN C 3 106 ? -64.201 -11.413 54.005 1.00 78.64 ? 106 GLN H CD 1 ATOM 4497 O OE1 . GLN C 3 106 ? -63.099 -11.128 54.474 1.00 80.25 ? 106 GLN H OE1 1 ATOM 4498 N NE2 . GLN C 3 106 ? -64.601 -12.667 53.827 1.00 78.40 ? 106 GLN H NE2 1 ATOM 4499 N N . GLY C 3 107 ? -65.833 -8.969 56.776 1.00 76.62 ? 107 GLY H N 1 ATOM 4500 C CA . GLY C 3 107 ? -67.046 -9.123 57.574 1.00 76.22 ? 107 GLY H CA 1 ATOM 4501 C C . GLY C 3 107 ? -67.736 -10.441 57.279 1.00 76.29 ? 107 GLY H C 1 ATOM 4502 O O . GLY C 3 107 ? -67.649 -10.959 56.164 1.00 76.23 ? 107 GLY H O 1 ATOM 4503 N N . THR C 3 108 ? -68.413 -10.986 58.286 1.00 76.68 ? 108 THR H N 1 ATOM 4504 C CA . THR C 3 108 ? -69.197 -12.210 58.130 1.00 76.54 ? 108 THR H CA 1 ATOM 4505 C C . THR C 3 108 ? -70.612 -11.982 58.641 1.00 76.80 ? 108 THR H C 1 ATOM 4506 O O . THR C 3 108 ? -70.815 -11.761 59.835 1.00 77.96 ? 108 THR H O 1 ATOM 4507 C CB . THR C 3 108 ? -68.569 -13.381 58.903 1.00 77.22 ? 108 THR H CB 1 ATOM 4508 O OG1 . THR C 3 108 ? -67.250 -13.628 58.407 1.00 77.68 ? 108 THR H OG1 1 ATOM 4509 C CG2 . THR C 3 108 ? -69.411 -14.647 58.752 1.00 77.01 ? 108 THR H CG2 1 ATOM 4510 N N . LEU C 3 109 ? -71.584 -12.029 57.733 1.00 76.20 ? 109 LEU H N 1 ATOM 4511 C CA . LEU C 3 109 ? -72.985 -11.871 58.098 1.00 75.98 ? 109 LEU H CA 1 ATOM 4512 C C . LEU C 3 109 ? -73.507 -13.171 58.701 1.00 76.16 ? 109 LEU H C 1 ATOM 4513 O O . LEU C 3 109 ? -73.618 -14.184 58.011 1.00 76.38 ? 109 LEU H O 1 ATOM 4514 C CB . LEU C 3 109 ? -73.823 -11.484 56.873 1.00 76.05 ? 109 LEU H CB 1 ATOM 4515 C CG . LEU C 3 109 ? -75.306 -11.169 57.117 1.00 76.04 ? 109 LEU H CG 1 ATOM 4516 C CD1 . LEU C 3 109 ? -75.467 -9.972 58.044 1.00 76.18 ? 109 LEU H CD1 1 ATOM 4517 C CD2 . LEU C 3 109 ? -76.021 -10.918 55.802 1.00 75.86 ? 109 LEU H CD2 1 ATOM 4518 N N . VAL C 3 110 ? -73.809 -13.135 59.995 1.00 76.06 ? 110 VAL H N 1 ATOM 4519 C CA . VAL C 3 110 ? -74.409 -14.269 60.685 1.00 75.77 ? 110 VAL H CA 1 ATOM 4520 C C . VAL C 3 110 ? -75.896 -13.999 60.875 1.00 75.66 ? 110 VAL H C 1 ATOM 4521 O O . VAL C 3 110 ? -76.277 -12.928 61.344 1.00 76.19 ? 110 VAL H O 1 ATOM 4522 C CB . VAL C 3 110 ? -73.750 -14.496 62.055 1.00 75.81 ? 110 VAL H CB 1 ATOM 4523 C CG1 . VAL C 3 110 ? -74.402 -15.663 62.778 1.00 75.67 ? 110 VAL H CG1 1 ATOM 4524 C CG2 . VAL C 3 110 ? -72.260 -14.735 61.886 1.00 76.20 ? 110 VAL H CG2 1 ATOM 4525 N N . THR C 3 111 ? -76.726 -14.969 60.495 1.00 75.81 ? 111 THR H N 1 ATOM 4526 C CA . THR C 3 111 ? -78.179 -14.854 60.610 1.00 75.77 ? 111 THR H CA 1 ATOM 4527 C C . THR C 3 111 ? -78.720 -15.974 61.495 1.00 75.88 ? 111 THR H C 1 ATOM 4528 O O . THR C 3 111 ? -78.443 -17.151 61.254 1.00 75.91 ? 111 THR H O 1 ATOM 4529 C CB . THR C 3 111 ? -78.864 -14.946 59.228 1.00 76.26 ? 111 THR H CB 1 ATOM 4530 O OG1 . THR C 3 111 ? -78.194 -14.091 58.294 1.00 76.94 ? 111 THR H OG1 1 ATOM 4531 C CG2 . THR C 3 111 ? -80.330 -14.540 59.323 1.00 76.13 ? 111 THR H CG2 1 ATOM 4532 N N . VAL C 3 112 ? -79.483 -15.600 62.520 1.00 75.70 ? 112 VAL H N 1 ATOM 4533 C CA . VAL C 3 112 ? -80.105 -16.565 63.417 1.00 75.66 ? 112 VAL H CA 1 ATOM 4534 C C . VAL C 3 112 ? -81.609 -16.574 63.181 1.00 76.10 ? 112 VAL H C 1 ATOM 4535 O O . VAL C 3 112 ? -82.303 -15.620 63.533 1.00 76.68 ? 112 VAL H O 1 ATOM 4536 C CB . VAL C 3 112 ? -79.832 -16.220 64.891 1.00 75.92 ? 112 VAL H CB 1 ATOM 4537 C CG1 . VAL C 3 112 ? -80.481 -17.254 65.807 1.00 76.68 ? 112 VAL H CG1 1 ATOM 4538 C CG2 . VAL C 3 112 ? -78.340 -16.137 65.147 1.00 75.67 ? 112 VAL H CG2 1 ATOM 4539 N N . SER C 3 113 ? -82.109 -17.650 62.578 1.00 75.94 ? 113 SER H N 1 ATOM 4540 C CA . SER C 3 113 ? -83.530 -17.759 62.263 1.00 75.76 ? 113 SER H CA 1 ATOM 4541 C C . SER C 3 113 ? -83.954 -19.212 62.063 1.00 76.07 ? 113 SER H C 1 ATOM 4542 O O . SER C 3 113 ? -83.229 -20.005 61.459 1.00 76.18 ? 113 SER H O 1 ATOM 4543 C CB . SER C 3 113 ? -83.855 -16.947 61.005 1.00 75.48 ? 113 SER H CB 1 ATOM 4544 O OG . SER C 3 113 ? -85.246 -16.951 60.734 1.00 75.08 ? 113 SER H OG 1 ATOM 4545 N N . ALA C 3 114 ? -85.139 -19.546 62.572 1.00 76.22 ? 114 ALA H N 1 ATOM 4546 C CA . ALA C 3 114 ? -85.729 -20.870 62.377 1.00 76.00 ? 114 ALA H CA 1 ATOM 4547 C C . ALA C 3 114 ? -86.284 -21.031 60.958 1.00 75.98 ? 114 ALA H C 1 ATOM 4548 O O . ALA C 3 114 ? -86.546 -22.150 60.513 1.00 75.84 ? 114 ALA H O 1 ATOM 4549 C CB . ALA C 3 114 ? -86.825 -21.113 63.405 1.00 75.53 ? 114 ALA H CB 1 ATOM 4550 N N . ALA C 3 115 ? -86.471 -19.911 60.258 1.00 76.04 ? 115 ALA H N 1 ATOM 4551 C CA . ALA C 3 115 ? -86.912 -19.928 58.865 1.00 76.34 ? 115 ALA H CA 1 ATOM 4552 C C . ALA C 3 115 ? -85.887 -20.640 57.987 1.00 76.60 ? 115 ALA H C 1 ATOM 4553 O O . ALA C 3 115 ? -84.683 -20.413 58.120 1.00 76.73 ? 115 ALA H O 1 ATOM 4554 C CB . ALA C 3 115 ? -87.137 -18.506 58.365 1.00 76.09 ? 115 ALA H CB 1 ATOM 4555 N N . LYS C 3 116 ? -86.371 -21.502 57.096 1.00 76.81 ? 116 LYS H N 1 ATOM 4556 C CA . LYS C 3 116 ? -85.494 -22.284 56.223 1.00 76.93 ? 116 LYS H CA 1 ATOM 4557 C C . LYS C 3 116 ? -85.042 -21.478 55.008 1.00 77.05 ? 116 LYS H C 1 ATOM 4558 O O . LYS C 3 116 ? -85.611 -20.431 54.693 1.00 76.84 ? 116 LYS H O 1 ATOM 4559 C CB . LYS C 3 116 ? -86.191 -23.571 55.769 1.00 76.73 ? 116 LYS H CB 1 ATOM 4560 C CG . LYS C 3 116 ? -86.320 -24.618 56.860 1.00 76.81 ? 116 LYS H CG 1 ATOM 4561 C CD . LYS C 3 116 ? -86.917 -25.906 56.315 1.00 77.02 ? 116 LYS H CD 1 ATOM 4562 C CE . LYS C 3 116 ? -87.010 -26.984 57.382 1.00 76.70 ? 116 LYS H CE 1 ATOM 4563 N NZ . LYS C 3 116 ? -87.674 -28.208 56.860 1.00 76.63 ? 116 LYS H NZ 1 ATOM 4564 N N . THR C 3 117 ? -84.009 -21.981 54.335 1.00 77.10 ? 117 THR H N 1 ATOM 4565 C CA . THR C 3 117 ? -83.471 -21.340 53.141 1.00 76.89 ? 117 THR H CA 1 ATOM 4566 C C . THR C 3 117 ? -84.424 -21.510 51.962 1.00 76.58 ? 117 THR H C 1 ATOM 4567 O O . THR C 3 117 ? -84.970 -22.591 51.746 1.00 76.45 ? 117 THR H O 1 ATOM 4568 C CB . THR C 3 117 ? -82.095 -21.927 52.761 1.00 77.22 ? 117 THR H CB 1 ATOM 4569 O OG1 . THR C 3 117 ? -81.157 -21.672 53.813 1.00 77.77 ? 117 THR H OG1 1 ATOM 4570 C CG2 . THR C 3 117 ? -81.577 -21.311 51.467 1.00 77.19 ? 117 THR H CG2 1 ATOM 4571 N N . THR C 3 118 ? -84.621 -20.430 51.211 1.00 76.61 ? 118 THR H N 1 ATOM 4572 C CA . THR C 3 118 ? -85.473 -20.441 50.027 1.00 76.83 ? 118 THR H CA 1 ATOM 4573 C C . THR C 3 118 ? -84.729 -19.792 48.864 1.00 76.97 ? 118 THR H C 1 ATOM 4574 O O . THR C 3 118 ? -84.251 -18.665 48.993 1.00 77.29 ? 118 THR H O 1 ATOM 4575 C CB . THR C 3 118 ? -86.778 -19.661 50.273 1.00 76.63 ? 118 THR H CB 1 ATOM 4576 O OG1 . THR C 3 118 ? -87.518 -20.282 51.330 1.00 76.73 ? 118 THR H OG1 1 ATOM 4577 C CG2 . THR C 3 118 ? -87.633 -19.623 49.012 1.00 76.49 ? 118 THR H CG2 1 ATOM 4578 N N . PRO C 3 119 ? -84.632 -20.498 47.721 1.00 77.08 ? 119 PRO H N 1 ATOM 4579 C CA . PRO C 3 119 ? -83.937 -19.934 46.568 1.00 77.26 ? 119 PRO H CA 1 ATOM 4580 C C . PRO C 3 119 ? -84.771 -18.846 45.891 1.00 77.57 ? 119 PRO H C 1 ATOM 4581 O O . PRO C 3 119 ? -86.000 -18.900 45.939 1.00 77.88 ? 119 PRO H O 1 ATOM 4582 C CB . PRO C 3 119 ? -83.764 -21.139 45.641 1.00 77.22 ? 119 PRO H CB 1 ATOM 4583 C CG . PRO C 3 119 ? -84.901 -22.026 45.966 1.00 77.31 ? 119 PRO H CG 1 ATOM 4584 C CD . PRO C 3 119 ? -85.176 -21.838 47.433 1.00 77.23 ? 119 PRO H CD 1 ATOM 4585 N N . PRO C 3 120 ? -84.107 -17.862 45.262 1.00 77.63 ? 120 PRO H N 1 ATOM 4586 C CA . PRO C 3 120 ? -84.821 -16.756 44.646 1.00 77.59 ? 120 PRO H CA 1 ATOM 4587 C C . PRO C 3 120 ? -85.433 -17.130 43.303 1.00 77.28 ? 120 PRO H C 1 ATOM 4588 O O . PRO C 3 120 ? -84.883 -17.961 42.578 1.00 76.53 ? 120 PRO H O 1 ATOM 4589 C CB . PRO C 3 120 ? -83.725 -15.707 44.446 1.00 77.64 ? 120 PRO H CB 1 ATOM 4590 C CG . PRO C 3 120 ? -82.496 -16.498 44.248 1.00 77.90 ? 120 PRO H CG 1 ATOM 4591 C CD . PRO C 3 120 ? -82.648 -17.738 45.087 1.00 78.00 ? 120 PRO H CD 1 ATOM 4592 N N . SER C 3 121 ? -86.571 -16.518 42.991 1.00 77.86 ? 121 SER H N 1 ATOM 4593 C CA . SER C 3 121 ? -87.122 -16.550 41.645 1.00 78.25 ? 121 SER H CA 1 ATOM 4594 C C . SER C 3 121 ? -86.652 -15.296 40.913 1.00 78.52 ? 121 SER H C 1 ATOM 4595 O O . SER C 3 121 ? -86.988 -14.176 41.308 1.00 78.35 ? 121 SER H O 1 ATOM 4596 C CB . SER C 3 121 ? -88.648 -16.598 41.690 1.00 78.72 ? 121 SER H CB 1 ATOM 4597 O OG . SER C 3 121 ? -89.096 -17.766 42.354 1.00 79.18 ? 121 SER H OG 1 ATOM 4598 N N . VAL C 3 122 ? -85.854 -15.490 39.865 1.00 78.56 ? 122 VAL H N 1 ATOM 4599 C CA . VAL C 3 122 ? -85.326 -14.382 39.075 1.00 78.22 ? 122 VAL H CA 1 ATOM 4600 C C . VAL C 3 122 ? -86.242 -14.116 37.887 1.00 78.24 ? 122 VAL H C 1 ATOM 4601 O O . VAL C 3 122 ? -86.486 -15.008 37.074 1.00 78.28 ? 122 VAL H O 1 ATOM 4602 C CB . VAL C 3 122 ? -83.907 -14.687 38.555 1.00 78.19 ? 122 VAL H CB 1 ATOM 4603 C CG1 . VAL C 3 122 ? -83.349 -13.490 37.792 1.00 78.00 ? 122 VAL H CG1 1 ATOM 4604 C CG2 . VAL C 3 122 ? -82.989 -15.063 39.709 1.00 78.38 ? 122 VAL H CG2 1 ATOM 4605 N N . TYR C 3 123 ? -86.750 -12.889 37.797 1.00 78.07 ? 123 TYR H N 1 ATOM 4606 C CA . TYR C 3 123 ? -87.592 -12.477 36.680 1.00 77.83 ? 123 TYR H CA 1 ATOM 4607 C C . TYR C 3 123 ? -86.941 -11.304 35.949 1.00 77.93 ? 123 TYR H C 1 ATOM 4608 O O . TYR C 3 123 ? -86.465 -10.365 36.591 1.00 78.20 ? 123 TYR H O 1 ATOM 4609 C CB . TYR C 3 123 ? -88.980 -12.071 37.175 1.00 77.39 ? 123 TYR H CB 1 ATOM 4610 C CG . TYR C 3 123 ? -89.706 -13.156 37.943 1.00 77.37 ? 123 TYR H CG 1 ATOM 4611 C CD1 . TYR C 3 123 ? -89.927 -14.410 37.377 1.00 77.26 ? 123 TYR H CD1 1 ATOM 4612 C CD2 . TYR C 3 123 ? -90.187 -12.923 39.229 1.00 77.49 ? 123 TYR H CD2 1 ATOM 4613 C CE1 . TYR C 3 123 ? -90.598 -15.407 38.077 1.00 77.30 ? 123 TYR H CE1 1 ATOM 4614 C CE2 . TYR C 3 123 ? -90.860 -13.913 39.937 1.00 77.45 ? 123 TYR H CE2 1 ATOM 4615 C CZ . TYR C 3 123 ? -91.062 -15.151 39.356 1.00 77.37 ? 123 TYR H CZ 1 ATOM 4616 O OH . TYR C 3 123 ? -91.728 -16.130 40.057 1.00 77.39 ? 123 TYR H OH 1 ATOM 4617 N N . PRO C 3 124 ? -86.912 -11.355 34.603 1.00 77.93 ? 124 PRO H N 1 ATOM 4618 C CA . PRO C 3 124 ? -86.354 -10.261 33.817 1.00 77.91 ? 124 PRO H CA 1 ATOM 4619 C C . PRO C 3 124 ? -87.350 -9.120 33.659 1.00 78.08 ? 124 PRO H C 1 ATOM 4620 O O . PRO C 3 124 ? -88.560 -9.342 33.730 1.00 78.10 ? 124 PRO H O 1 ATOM 4621 C CB . PRO C 3 124 ? -86.078 -10.917 32.465 1.00 77.95 ? 124 PRO H CB 1 ATOM 4622 C CG . PRO C 3 124 ? -87.129 -11.951 32.342 1.00 78.07 ? 124 PRO H CG 1 ATOM 4623 C CD . PRO C 3 124 ? -87.408 -12.445 33.740 1.00 78.14 ? 124 PRO H CD 1 ATOM 4624 N N . LEU C 3 125 ? -86.839 -7.910 33.447 1.00 78.14 ? 125 LEU H N 1 ATOM 4625 C CA . LEU C 3 125 ? -87.684 -6.736 33.260 1.00 78.10 ? 125 LEU H CA 1 ATOM 4626 C C . LEU C 3 125 ? -87.245 -5.967 32.020 1.00 78.38 ? 125 LEU H C 1 ATOM 4627 O O . LEU C 3 125 ? -86.088 -5.555 31.914 1.00 78.41 ? 125 LEU H O 1 ATOM 4628 C CB . LEU C 3 125 ? -87.621 -5.829 34.490 1.00 77.60 ? 125 LEU H CB 1 ATOM 4629 C CG . LEU C 3 125 ? -87.886 -6.489 35.846 1.00 77.23 ? 125 LEU H CG 1 ATOM 4630 C CD1 . LEU C 3 125 ? -87.691 -5.483 36.970 1.00 76.82 ? 125 LEU H CD1 1 ATOM 4631 C CD2 . LEU C 3 125 ? -89.285 -7.089 35.896 1.00 77.19 ? 125 LEU H CD2 1 ATOM 4632 N N . ALA C 3 126 ? -88.174 -5.790 31.083 1.00 78.62 ? 126 ALA H N 1 ATOM 4633 C CA . ALA C 3 126 ? -87.916 -5.041 29.855 1.00 78.81 ? 126 ALA H CA 1 ATOM 4634 C C . ALA C 3 126 ? -89.180 -4.311 29.409 1.00 79.12 ? 126 ALA H C 1 ATOM 4635 O O . ALA C 3 126 ? -90.290 -4.753 29.709 1.00 79.19 ? 126 ALA H O 1 ATOM 4636 C CB . ALA C 3 126 ? -87.437 -5.977 28.761 1.00 78.92 ? 126 ALA H CB 1 ATOM 4637 N N . PRO C 3 127 ? -89.017 -3.193 28.679 1.00 79.33 ? 127 PRO H N 1 ATOM 4638 C CA . PRO C 3 127 ? -90.159 -2.378 28.263 1.00 79.44 ? 127 PRO H CA 1 ATOM 4639 C C . PRO C 3 127 ? -90.976 -3.016 27.138 1.00 79.50 ? 127 PRO H C 1 ATOM 4640 O O . PRO C 3 127 ? -90.489 -3.912 26.449 1.00 79.60 ? 127 PRO H O 1 ATOM 4641 C CB . PRO C 3 127 ? -89.500 -1.082 27.783 1.00 79.81 ? 127 PRO H CB 1 ATOM 4642 C CG . PRO C 3 127 ? -88.161 -1.503 27.305 1.00 79.72 ? 127 PRO H CG 1 ATOM 4643 C CD . PRO C 3 127 ? -87.739 -2.636 28.195 1.00 79.42 ? 127 PRO H CD 1 ATOM 4644 N N . ASN C 3 134 ? -81.677 11.040 26.593 1.00 80.24 ? 134 ASN H N 1 ATOM 4645 C CA . ASN C 3 134 ? -82.521 10.910 25.408 1.00 80.43 ? 134 ASN H CA 1 ATOM 4646 C C . ASN C 3 134 ? -82.190 9.651 24.607 1.00 80.74 ? 134 ASN H C 1 ATOM 4647 O O . ASN C 3 134 ? -81.029 9.412 24.270 1.00 80.88 ? 134 ASN H O 1 ATOM 4648 C CB . ASN C 3 134 ? -82.379 12.147 24.512 0.50 80.01 ? 134 ASN H CB 1 ATOM 4649 C CG . ASN C 3 134 ? -83.130 13.356 25.050 0.50 79.65 ? 134 ASN H CG 1 ATOM 4650 O OD1 . ASN C 3 134 ? -83.811 14.057 24.302 0.50 79.42 ? 134 ASN H OD1 1 ATOM 4651 N ND2 . ASN C 3 134 ? -83.009 13.603 26.350 0.50 79.57 ? 134 ASN H ND2 1 ATOM 4652 N N . SER C 3 135 ? -83.220 8.858 24.306 1.00 80.76 ? 135 SER H N 1 ATOM 4653 C CA . SER C 3 135 ? -83.078 7.610 23.544 1.00 80.57 ? 135 SER H CA 1 ATOM 4654 C C . SER C 3 135 ? -82.006 6.685 24.129 1.00 80.59 ? 135 SER H C 1 ATOM 4655 O O . SER C 3 135 ? -80.938 6.500 23.539 1.00 80.44 ? 135 SER H O 1 ATOM 4656 C CB . SER C 3 135 ? -82.795 7.903 22.063 1.00 80.62 ? 135 SER H CB 1 ATOM 4657 O OG . SER C 3 135 ? -81.521 8.496 21.873 1.00 80.69 ? 135 SER H OG 1 ATOM 4658 N N . MET C 3 136 ? -82.302 6.113 25.294 1.00 80.66 ? 136 MET H N 1 ATOM 4659 C CA . MET C 3 136 ? -81.395 5.173 25.951 1.00 80.56 ? 136 MET H CA 1 ATOM 4660 C C . MET C 3 136 ? -82.170 4.214 26.857 1.00 80.54 ? 136 MET H C 1 ATOM 4661 O O . MET C 3 136 ? -82.794 4.634 27.833 1.00 80.73 ? 136 MET H O 1 ATOM 4662 C CB . MET C 3 136 ? -80.339 5.930 26.758 1.00 80.62 ? 136 MET H CB 1 ATOM 4663 C CG . MET C 3 136 ? -79.220 5.043 27.281 1.00 80.72 ? 136 MET H CG 1 ATOM 4664 S SD . MET C 3 136 ? -77.683 5.932 27.584 1.00 80.94 ? 136 MET H SD 1 ATOM 4665 C CE . MET C 3 136 ? -77.198 6.360 25.913 1.00 80.84 ? 136 MET H CE 1 ATOM 4666 N N . VAL C 3 137 ? -82.117 2.926 26.526 1.00 80.33 ? 137 VAL H N 1 ATOM 4667 C CA . VAL C 3 137 ? -82.929 1.909 27.199 1.00 80.12 ? 137 VAL H CA 1 ATOM 4668 C C . VAL C 3 137 ? -82.471 1.646 28.637 1.00 79.80 ? 137 VAL H C 1 ATOM 4669 O O . VAL C 3 137 ? -81.286 1.767 28.954 1.00 79.65 ? 137 VAL H O 1 ATOM 4670 C CB . VAL C 3 137 ? -82.922 0.572 26.409 1.00 80.00 ? 137 VAL H CB 1 ATOM 4671 C CG1 . VAL C 3 137 ? -81.539 -0.072 26.443 1.00 79.89 ? 137 VAL H CG1 1 ATOM 4672 C CG2 . VAL C 3 137 ? -83.975 -0.383 26.955 1.00 80.14 ? 137 VAL H CG2 1 ATOM 4673 N N . THR C 3 138 ? -83.429 1.299 29.496 1.00 79.75 ? 138 THR H N 1 ATOM 4674 C CA . THR C 3 138 ? -83.150 0.888 30.872 1.00 79.79 ? 138 THR H CA 1 ATOM 4675 C C . THR C 3 138 ? -83.762 -0.491 31.119 1.00 79.59 ? 138 THR H C 1 ATOM 4676 O O . THR C 3 138 ? -84.973 -0.667 30.987 1.00 79.46 ? 138 THR H O 1 ATOM 4677 C CB . THR C 3 138 ? -83.735 1.885 31.893 1.00 79.95 ? 138 THR H CB 1 ATOM 4678 O OG1 . THR C 3 138 ? -83.266 3.207 31.601 1.00 80.39 ? 138 THR H OG1 1 ATOM 4679 C CG2 . THR C 3 138 ? -83.327 1.505 33.312 1.00 79.67 ? 138 THR H CG2 1 ATOM 4680 N N . LEU C 3 139 ? -82.918 -1.459 31.468 1.00 79.56 ? 139 LEU H N 1 ATOM 4681 C CA . LEU C 3 139 ? -83.362 -2.829 31.730 1.00 79.36 ? 139 LEU H CA 1 ATOM 4682 C C . LEU C 3 139 ? -83.347 -3.107 33.228 1.00 79.24 ? 139 LEU H C 1 ATOM 4683 O O . LEU C 3 139 ? -82.716 -2.377 33.995 1.00 79.05 ? 139 LEU H O 1 ATOM 4684 C CB . LEU C 3 139 ? -82.461 -3.829 31.003 1.00 78.76 ? 139 LEU H CB 1 ATOM 4685 C CG . LEU C 3 139 ? -82.221 -3.551 29.517 1.00 78.53 ? 139 LEU H CG 1 ATOM 4686 C CD1 . LEU C 3 139 ? -81.243 -4.560 28.942 1.00 78.67 ? 139 LEU H CD1 1 ATOM 4687 C CD2 . LEU C 3 139 ? -83.532 -3.565 28.744 1.00 78.38 ? 139 LEU H CD2 1 ATOM 4688 N N . GLY C 3 140 ? -84.037 -4.169 33.637 1.00 79.32 ? 140 GLY H N 1 ATOM 4689 C CA . GLY C 3 140 ? -84.171 -4.505 35.054 1.00 79.53 ? 140 GLY H CA 1 ATOM 4690 C C . GLY C 3 140 ? -84.062 -5.989 35.347 1.00 80.24 ? 140 GLY H C 1 ATOM 4691 O O . GLY C 3 140 ? -83.938 -6.806 34.432 1.00 80.67 ? 140 GLY H O 1 ATOM 4692 N N . CYS C 3 141 ? -84.119 -6.332 36.632 1.00 80.26 ? 141 CYS H N 1 ATOM 4693 C CA . CYS C 3 141 ? -83.945 -7.711 37.079 1.00 79.09 ? 141 CYS H CA 1 ATOM 4694 C C . CYS C 3 141 ? -84.529 -7.907 38.477 1.00 78.17 ? 141 CYS H C 1 ATOM 4695 O O . CYS C 3 141 ? -83.956 -7.446 39.459 1.00 78.13 ? 141 CYS H O 1 ATOM 4696 C CB . CYS C 3 141 ? -82.460 -8.067 37.083 1.00 79.97 ? 141 CYS H CB 1 ATOM 4697 S SG . CYS C 3 141 ? -82.113 -9.792 37.435 1.00 81.34 ? 141 CYS H SG 1 ATOM 4698 N N . LEU C 3 142 ? -85.663 -8.603 38.556 1.00 77.78 ? 142 LEU H N 1 ATOM 4699 C CA . LEU C 3 142 ? -86.390 -8.780 39.817 1.00 77.80 ? 142 LEU H CA 1 ATOM 4700 C C . LEU C 3 142 ? -86.038 -10.109 40.497 1.00 77.80 ? 142 LEU H C 1 ATOM 4701 O O . LEU C 3 142 ? -86.395 -11.180 40.003 1.00 78.01 ? 142 LEU H O 1 ATOM 4702 C CB . LEU C 3 142 ? -87.900 -8.707 39.561 1.00 77.49 ? 142 LEU H CB 1 ATOM 4703 C CG . LEU C 3 142 ? -88.825 -8.747 40.781 1.00 77.54 ? 142 LEU H CG 1 ATOM 4704 C CD1 . LEU C 3 142 ? -88.537 -7.590 41.721 1.00 77.46 ? 142 LEU H CD1 1 ATOM 4705 C CD2 . LEU C 3 142 ? -90.281 -8.728 40.340 1.00 77.58 ? 142 LEU H CD2 1 ATOM 4706 N N . VAL C 3 143 ? -85.342 -10.025 41.631 1.00 77.38 ? 143 VAL H N 1 ATOM 4707 C CA . VAL C 3 143 ? -84.965 -11.202 42.420 1.00 77.18 ? 143 VAL H CA 1 ATOM 4708 C C . VAL C 3 143 ? -85.887 -11.321 43.637 1.00 77.63 ? 143 VAL H C 1 ATOM 4709 O O . VAL C 3 143 ? -85.625 -10.729 44.688 1.00 77.81 ? 143 VAL H O 1 ATOM 4710 C CB . VAL C 3 143 ? -83.496 -11.110 42.882 1.00 75.60 ? 143 VAL H CB 1 ATOM 4711 C CG1 . VAL C 3 143 ? -83.099 -12.351 43.666 1.00 75.23 ? 143 VAL H CG1 1 ATOM 4712 C CG2 . VAL C 3 143 ? -82.580 -10.918 41.685 1.00 75.05 ? 143 VAL H CG2 1 ATOM 4713 N N . LYS C 3 144 ? -86.957 -12.103 43.490 1.00 77.64 ? 144 LYS H N 1 ATOM 4714 C CA . LYS C 3 144 ? -88.071 -12.087 44.440 1.00 77.61 ? 144 LYS H CA 1 ATOM 4715 C C . LYS C 3 144 ? -88.169 -13.355 45.289 1.00 77.91 ? 144 LYS H C 1 ATOM 4716 O O . LYS C 3 144 ? -88.054 -14.469 44.776 1.00 78.34 ? 144 LYS H O 1 ATOM 4717 C CB . LYS C 3 144 ? -89.389 -11.884 43.685 1.00 78.05 ? 144 LYS H CB 1 ATOM 4718 C CG . LYS C 3 144 ? -90.600 -11.658 44.584 1.00 78.02 ? 144 LYS H CG 1 ATOM 4719 C CD . LYS C 3 144 ? -91.855 -11.377 43.770 1.00 78.15 ? 144 LYS H CD 1 ATOM 4720 C CE . LYS C 3 144 ? -93.069 -11.175 44.667 1.00 78.43 ? 144 LYS H CE 1 ATOM 4721 N NZ . LYS C 3 144 ? -92.913 -10.012 45.586 1.00 78.58 ? 144 LYS H NZ 1 ATOM 4722 N N . GLY C 3 145 ? -88.395 -13.166 46.589 1.00 77.59 ? 145 GLY H N 1 ATOM 4723 C CA . GLY C 3 145 ? -88.757 -14.254 47.495 1.00 76.61 ? 145 GLY H CA 1 ATOM 4724 C C . GLY C 3 145 ? -87.625 -15.209 47.811 1.00 76.19 ? 145 GLY H C 1 ATOM 4725 O O . GLY C 3 145 ? -87.644 -16.361 47.380 1.00 76.60 ? 145 GLY H O 1 ATOM 4726 N N . TYR C 3 146 ? -86.642 -14.735 48.572 1.00 75.76 ? 146 TYR H N 1 ATOM 4727 C CA . TYR C 3 146 ? -85.518 -15.578 48.984 1.00 75.47 ? 146 TYR H CA 1 ATOM 4728 C C . TYR C 3 146 ? -85.135 -15.355 50.442 1.00 74.92 ? 146 TYR H C 1 ATOM 4729 O O . TYR C 3 146 ? -85.457 -14.322 51.034 1.00 75.01 ? 146 TYR H O 1 ATOM 4730 C CB . TYR C 3 146 ? -84.301 -15.334 48.087 1.00 75.29 ? 146 TYR H CB 1 ATOM 4731 C CG . TYR C 3 146 ? -83.719 -13.938 48.181 1.00 75.02 ? 146 TYR H CG 1 ATOM 4732 C CD1 . TYR C 3 146 ? -84.078 -12.950 47.270 1.00 75.03 ? 146 TYR H CD1 1 ATOM 4733 C CD2 . TYR C 3 146 ? -82.800 -13.611 49.174 1.00 75.08 ? 146 TYR H CD2 1 ATOM 4734 C CE1 . TYR C 3 146 ? -83.543 -11.669 47.349 1.00 75.22 ? 146 TYR H CE1 1 ATOM 4735 C CE2 . TYR C 3 146 ? -82.263 -12.336 49.264 1.00 75.32 ? 146 TYR H CE2 1 ATOM 4736 C CZ . TYR C 3 146 ? -82.636 -11.368 48.348 1.00 75.27 ? 146 TYR H CZ 1 ATOM 4737 O OH . TYR C 3 146 ? -82.102 -10.102 48.434 1.00 75.10 ? 146 TYR H OH 1 ATOM 4738 N N . PHE C 3 147 ? -84.436 -16.334 51.004 1.00 73.87 ? 147 PHE H N 1 ATOM 4739 C CA . PHE C 3 147 ? -83.949 -16.255 52.373 1.00 74.19 ? 147 PHE H CA 1 ATOM 4740 C C . PHE C 3 147 ? -82.815 -17.262 52.548 1.00 74.80 ? 147 PHE H C 1 ATOM 4741 O O . PHE C 3 147 ? -82.903 -18.375 52.034 1.00 74.81 ? 147 PHE H O 1 ATOM 4742 C CB . PHE C 3 147 ? -85.085 -16.561 53.351 1.00 73.01 ? 147 PHE H CB 1 ATOM 4743 C CG . PHE C 3 147 ? -84.748 -16.278 54.786 1.00 73.08 ? 147 PHE H CG 1 ATOM 4744 C CD1 . PHE C 3 147 ? -84.857 -14.993 55.297 1.00 72.84 ? 147 PHE H CD1 1 ATOM 4745 C CD2 . PHE C 3 147 ? -84.334 -17.299 55.632 1.00 72.73 ? 147 PHE H CD2 1 ATOM 4746 C CE1 . PHE C 3 147 ? -84.552 -14.726 56.623 1.00 72.70 ? 147 PHE H CE1 1 ATOM 4747 C CE2 . PHE C 3 147 ? -84.029 -17.041 56.958 1.00 72.72 ? 147 PHE H CE2 1 ATOM 4748 C CZ . PHE C 3 147 ? -84.137 -15.752 57.454 1.00 72.84 ? 147 PHE H CZ 1 ATOM 4749 N N . PRO C 3 148 ? -81.733 -16.874 53.249 1.00 75.61 ? 148 PRO H N 1 ATOM 4750 C CA . PRO C 3 148 ? -81.426 -15.577 53.842 1.00 76.53 ? 148 PRO H CA 1 ATOM 4751 C C . PRO C 3 148 ? -80.660 -14.670 52.880 1.00 76.83 ? 148 PRO H C 1 ATOM 4752 O O . PRO C 3 148 ? -80.442 -15.036 51.724 1.00 77.20 ? 148 PRO H O 1 ATOM 4753 C CB . PRO C 3 148 ? -80.523 -15.960 55.012 1.00 76.07 ? 148 PRO H CB 1 ATOM 4754 C CG . PRO C 3 148 ? -79.744 -17.111 54.485 1.00 75.74 ? 148 PRO H CG 1 ATOM 4755 C CD . PRO C 3 148 ? -80.654 -17.843 53.516 1.00 75.74 ? 148 PRO H CD 1 ATOM 4756 N N . GLU C 3 149 ? -80.259 -13.497 53.366 1.00 76.73 ? 149 GLU H N 1 ATOM 4757 C CA . GLU C 3 149 ? -79.286 -12.656 52.669 1.00 77.28 ? 149 GLU H CA 1 ATOM 4758 C C . GLU C 3 149 ? -77.922 -13.354 52.681 1.00 77.42 ? 149 GLU H C 1 ATOM 4759 O O . GLU C 3 149 ? -77.726 -14.305 53.437 1.00 78.47 ? 149 GLU H O 1 ATOM 4760 C CB . GLU C 3 149 ? -79.173 -11.289 53.357 1.00 78.53 ? 149 GLU H CB 1 ATOM 4761 C CG . GLU C 3 149 ? -80.319 -10.333 53.061 1.00 79.94 ? 149 GLU H CG 1 ATOM 4762 C CD . GLU C 3 149 ? -80.106 -9.537 51.782 1.00 81.75 ? 149 GLU H CD 1 ATOM 4763 O OE1 . GLU C 3 149 ? -80.191 -10.129 50.686 1.00 82.75 ? 149 GLU H OE1 1 ATOM 4764 O OE2 . GLU C 3 149 ? -79.862 -8.315 51.874 1.00 82.01 ? 149 GLU H OE2 1 ATOM 4765 N N . PRO C 3 150 ? -76.975 -12.902 51.836 1.00 76.73 ? 150 PRO H N 1 ATOM 4766 C CA . PRO C 3 150 ? -77.075 -11.905 50.786 1.00 76.58 ? 150 PRO H CA 1 ATOM 4767 C C . PRO C 3 150 ? -77.252 -12.529 49.401 1.00 76.53 ? 150 PRO H C 1 ATOM 4768 O O . PRO C 3 150 ? -77.301 -13.753 49.269 1.00 76.31 ? 150 PRO H O 1 ATOM 4769 C CB . PRO C 3 150 ? -75.723 -11.200 50.872 1.00 76.84 ? 150 PRO H CB 1 ATOM 4770 C CG . PRO C 3 150 ? -74.769 -12.268 51.370 1.00 76.70 ? 150 PRO H CG 1 ATOM 4771 C CD . PRO C 3 150 ? -75.593 -13.400 51.943 1.00 76.87 ? 150 PRO H CD 1 ATOM 4772 N N . VAL C 3 151 ? -77.348 -11.675 48.385 1.00 76.72 ? 151 VAL H N 1 ATOM 4773 C CA . VAL C 3 151 ? -77.472 -12.109 46.998 1.00 76.39 ? 151 VAL H CA 1 ATOM 4774 C C . VAL C 3 151 ? -76.578 -11.247 46.112 1.00 76.06 ? 151 VAL H C 1 ATOM 4775 O O . VAL C 3 151 ? -76.557 -10.024 46.247 1.00 76.16 ? 151 VAL H O 1 ATOM 4776 C CB . VAL C 3 151 ? -78.927 -12.000 46.508 1.00 76.11 ? 151 VAL H CB 1 ATOM 4777 C CG1 . VAL C 3 151 ? -79.027 -12.361 45.035 1.00 76.60 ? 151 VAL H CG1 1 ATOM 4778 C CG2 . VAL C 3 151 ? -79.826 -12.895 47.334 1.00 75.67 ? 151 VAL H CG2 1 ATOM 4779 N N . THR C 3 152 ? -75.842 -11.894 45.212 1.00 76.41 ? 152 THR H N 1 ATOM 4780 C CA . THR C 3 152 ? -74.921 -11.205 44.314 1.00 76.84 ? 152 THR H CA 1 ATOM 4781 C C . THR C 3 152 ? -75.528 -11.082 42.920 1.00 77.07 ? 152 THR H C 1 ATOM 4782 O O . THR C 3 152 ? -75.685 -12.080 42.214 1.00 77.27 ? 152 THR H O 1 ATOM 4783 C CB . THR C 3 152 ? -73.576 -11.953 44.218 1.00 77.16 ? 152 THR H CB 1 ATOM 4784 O OG1 . THR C 3 152 ? -72.888 -11.861 45.472 1.00 77.75 ? 152 THR H OG1 1 ATOM 4785 C CG2 . THR C 3 152 ? -72.697 -11.364 43.117 1.00 76.89 ? 152 THR H CG2 1 ATOM 4786 N N . VAL C 3 153 ? -75.871 -9.854 42.537 1.00 77.00 ? 153 VAL H N 1 ATOM 4787 C CA . VAL C 3 153 ? -76.394 -9.570 41.204 1.00 77.27 ? 153 VAL H CA 1 ATOM 4788 C C . VAL C 3 153 ? -75.346 -8.824 40.381 1.00 77.73 ? 153 VAL H C 1 ATOM 4789 O O . VAL C 3 153 ? -74.774 -7.835 40.840 1.00 78.13 ? 153 VAL H O 1 ATOM 4790 C CB . VAL C 3 153 ? -77.677 -8.717 41.272 1.00 76.86 ? 153 VAL H CB 1 ATOM 4791 C CG1 . VAL C 3 153 ? -78.183 -8.403 39.872 1.00 76.54 ? 153 VAL H CG1 1 ATOM 4792 C CG2 . VAL C 3 153 ? -78.748 -9.430 42.080 1.00 76.68 ? 153 VAL H CG2 1 ATOM 4793 N N . THR C 3 154 ? -75.089 -9.323 39.175 1.00 77.82 ? 154 THR H N 1 ATOM 4794 C CA . THR C 3 154 ? -74.195 -8.666 38.220 1.00 77.83 ? 154 THR H CA 1 ATOM 4795 C C . THR C 3 154 ? -74.776 -8.810 36.816 1.00 78.17 ? 154 THR H C 1 ATOM 4796 O O . THR C 3 154 ? -75.804 -9.466 36.631 1.00 78.50 ? 154 THR H O 1 ATOM 4797 C CB . THR C 3 154 ? -72.773 -9.273 38.254 1.00 77.90 ? 154 THR H CB 1 ATOM 4798 O OG1 . THR C 3 154 ? -72.823 -10.653 37.869 1.00 77.88 ? 154 THR H OG1 1 ATOM 4799 C CG2 . THR C 3 154 ? -72.169 -9.157 39.647 1.00 78.03 ? 154 THR H CG2 1 ATOM 4800 N N . TRP C 3 155 ? -74.121 -8.195 35.833 1.00 78.11 ? 155 TRP H N 1 ATOM 4801 C CA . TRP C 3 155 ? -74.605 -8.210 34.453 1.00 78.02 ? 155 TRP H CA 1 ATOM 4802 C C . TRP C 3 155 ? -73.522 -8.671 33.488 1.00 77.93 ? 155 TRP H C 1 ATOM 4803 O O . TRP C 3 155 ? -72.421 -8.117 33.469 1.00 77.74 ? 155 TRP H O 1 ATOM 4804 C CB . TRP C 3 155 ? -75.101 -6.822 34.061 1.00 77.75 ? 155 TRP H CB 1 ATOM 4805 C CG . TRP C 3 155 ? -76.291 -6.392 34.849 1.00 77.74 ? 155 TRP H CG 1 ATOM 4806 C CD1 . TRP C 3 155 ? -76.289 -5.766 36.060 1.00 77.77 ? 155 TRP H CD1 1 ATOM 4807 C CD2 . TRP C 3 155 ? -77.665 -6.569 34.491 1.00 77.75 ? 155 TRP H CD2 1 ATOM 4808 N NE1 . TRP C 3 155 ? -77.577 -5.535 36.476 1.00 77.79 ? 155 TRP H NE1 1 ATOM 4809 C CE2 . TRP C 3 155 ? -78.442 -6.018 35.531 1.00 77.68 ? 155 TRP H CE2 1 ATOM 4810 C CE3 . TRP C 3 155 ? -78.315 -7.136 33.388 1.00 77.82 ? 155 TRP H CE3 1 ATOM 4811 C CZ2 . TRP C 3 155 ? -79.837 -6.017 35.502 1.00 77.68 ? 155 TRP H CZ2 1 ATOM 4812 C CZ3 . TRP C 3 155 ? -79.703 -7.135 33.361 1.00 77.79 ? 155 TRP H CZ3 1 ATOM 4813 C CH2 . TRP C 3 155 ? -80.447 -6.577 34.411 1.00 77.71 ? 155 TRP H CH2 1 ATOM 4814 N N . ASN C 3 156 ? -73.848 -9.686 32.688 1.00 78.18 ? 156 ASN H N 1 ATOM 4815 C CA . ASN C 3 156 ? -72.908 -10.274 31.733 1.00 78.46 ? 156 ASN H CA 1 ATOM 4816 C C . ASN C 3 156 ? -71.585 -10.649 32.404 1.00 78.76 ? 156 ASN H C 1 ATOM 4817 O O . ASN C 3 156 ? -70.508 -10.273 31.936 1.00 78.84 ? 156 ASN H O 1 ATOM 4818 C CB . ASN C 3 156 ? -72.674 -9.321 30.554 1.00 78.46 ? 156 ASN H CB 1 ATOM 4819 C CG . ASN C 3 156 ? -73.965 -8.929 29.850 1.00 78.52 ? 156 ASN H CG 1 ATOM 4820 O OD1 . ASN C 3 156 ? -75.018 -9.527 30.074 1.00 78.52 ? 156 ASN H OD1 1 ATOM 4821 N ND2 . ASN C 3 156 ? -73.886 -7.918 28.992 1.00 78.53 ? 156 ASN H ND2 1 ATOM 4822 N N . SER C 3 157 ? -71.689 -11.389 33.508 1.00 78.98 ? 157 SER H N 1 ATOM 4823 C CA . SER C 3 157 ? -70.534 -11.799 34.314 1.00 78.91 ? 157 SER H CA 1 ATOM 4824 C C . SER C 3 157 ? -69.706 -10.601 34.793 1.00 78.81 ? 157 SER H C 1 ATOM 4825 O O . SER C 3 157 ? -68.475 -10.637 34.783 1.00 78.73 ? 157 SER H O 1 ATOM 4826 C CB . SER C 3 157 ? -69.657 -12.788 33.536 1.00 79.37 ? 157 SER H CB 1 ATOM 4827 O OG . SER C 3 157 ? -70.430 -13.862 33.028 1.00 79.64 ? 157 SER H OG 1 ATOM 4828 N N . GLY C 3 158 ? -70.395 -9.543 35.214 1.00 78.93 ? 158 GLY H N 1 ATOM 4829 C CA . GLY C 3 158 ? -69.742 -8.344 35.733 1.00 78.98 ? 158 GLY H CA 1 ATOM 4830 C C . GLY C 3 158 ? -69.074 -7.477 34.677 1.00 78.88 ? 158 GLY H C 1 ATOM 4831 O O . GLY C 3 158 ? -68.204 -6.667 35.000 1.00 78.69 ? 158 GLY H O 1 ATOM 4832 N N . SER C 3 159 ? -69.481 -7.637 33.418 1.00 79.02 ? 159 SER H N 1 ATOM 4833 C CA . SER C 3 159 ? -68.936 -6.829 32.326 1.00 79.16 ? 159 SER H CA 1 ATOM 4834 C C . SER C 3 159 ? -69.514 -5.421 32.375 1.00 79.42 ? 159 SER H C 1 ATOM 4835 O O . SER C 3 159 ? -68.772 -4.438 32.390 1.00 79.74 ? 159 SER H O 1 ATOM 4836 C CB . SER C 3 159 ? -69.239 -7.470 30.970 1.00 79.16 ? 159 SER H CB 1 ATOM 4837 O OG . SER C 3 159 ? -68.613 -8.735 30.853 1.00 79.33 ? 159 SER H OG 1 ATOM 4838 N N . LEU C 3 160 ? -70.842 -5.333 32.402 1.00 79.28 ? 160 LEU H N 1 ATOM 4839 C CA . LEU C 3 160 ? -71.529 -4.051 32.522 1.00 79.29 ? 160 LEU H CA 1 ATOM 4840 C C . LEU C 3 160 ? -71.527 -3.602 33.983 1.00 79.54 ? 160 LEU H C 1 ATOM 4841 O O . LEU C 3 160 ? -72.507 -3.794 34.708 1.00 79.82 ? 160 LEU H O 1 ATOM 4842 C CB . LEU C 3 160 ? -72.965 -4.155 31.995 1.00 79.75 ? 160 LEU H CB 1 ATOM 4843 C CG . LEU C 3 160 ? -73.128 -4.621 30.545 1.00 80.16 ? 160 LEU H CG 1 ATOM 4844 C CD1 . LEU C 3 160 ? -74.604 -4.714 30.182 1.00 80.09 ? 160 LEU H CD1 1 ATOM 4845 C CD2 . LEU C 3 160 ? -72.394 -3.695 29.582 1.00 80.40 ? 160 LEU H CD2 1 ATOM 4846 N N . SER C 3 161 ? -70.412 -3.011 34.407 1.00 79.28 ? 161 SER H N 1 ATOM 4847 C CA . SER C 3 161 ? -70.241 -2.567 35.791 1.00 78.78 ? 161 SER H CA 1 ATOM 4848 C C . SER C 3 161 ? -70.851 -1.184 36.007 1.00 78.52 ? 161 SER H C 1 ATOM 4849 O O . SER C 3 161 ? -71.684 -0.996 36.897 1.00 78.48 ? 161 SER H O 1 ATOM 4850 C CB . SER C 3 161 ? -68.756 -2.544 36.163 1.00 78.70 ? 161 SER H CB 1 ATOM 4851 O OG . SER C 3 161 ? -68.024 -1.701 35.290 1.00 78.64 ? 161 SER H OG 1 ATOM 4852 N N . SER C 3 162 ? -70.430 -0.222 35.188 1.00 78.11 ? 162 SER H N 1 ATOM 4853 C CA . SER C 3 162 ? -70.881 1.163 35.319 1.00 77.80 ? 162 SER H CA 1 ATOM 4854 C C . SER C 3 162 ? -72.339 1.316 34.893 1.00 77.46 ? 162 SER H C 1 ATOM 4855 O O . SER C 3 162 ? -72.836 0.560 34.057 1.00 77.28 ? 162 SER H O 1 ATOM 4856 C CB . SER C 3 162 ? -69.995 2.092 34.484 1.00 77.79 ? 162 SER H CB 1 ATOM 4857 O OG . SER C 3 162 ? -70.302 3.453 34.734 1.00 77.79 ? 162 SER H OG 1 ATOM 4858 N N . GLY C 3 163 ? -73.017 2.300 35.481 1.00 77.31 ? 163 GLY H N 1 ATOM 4859 C CA . GLY C 3 163 ? -74.418 2.579 35.169 1.00 76.94 ? 163 GLY H CA 1 ATOM 4860 C C . GLY C 3 163 ? -75.385 1.548 35.725 1.00 76.30 ? 163 GLY H C 1 ATOM 4861 O O . GLY C 3 163 ? -76.458 1.333 35.157 1.00 75.92 ? 163 GLY H O 1 ATOM 4862 N N . VAL C 3 164 ? -75.011 0.920 36.839 1.00 76.18 ? 164 VAL H N 1 ATOM 4863 C CA . VAL C 3 164 ? -75.832 -0.116 37.463 1.00 76.28 ? 164 VAL H CA 1 ATOM 4864 C C . VAL C 3 164 ? -76.299 0.330 38.846 1.00 76.55 ? 164 VAL H C 1 ATOM 4865 O O . VAL C 3 164 ? -75.514 0.864 39.631 1.00 76.83 ? 164 VAL H O 1 ATOM 4866 C CB . VAL C 3 164 ? -75.053 -1.444 37.599 1.00 75.66 ? 164 VAL H CB 1 ATOM 4867 C CG1 . VAL C 3 164 ? -75.894 -2.488 38.317 1.00 75.37 ? 164 VAL H CG1 1 ATOM 4868 C CG2 . VAL C 3 164 ? -74.629 -1.953 36.232 1.00 75.50 ? 164 VAL H CG2 1 ATOM 4869 N N . HIS C 3 165 ? -77.583 0.113 39.129 1.00 76.48 ? 165 HIS H N 1 ATOM 4870 C CA . HIS C 3 165 ? -78.160 0.383 40.445 1.00 76.21 ? 165 HIS H CA 1 ATOM 4871 C C . HIS C 3 165 ? -78.778 -0.896 40.998 1.00 76.21 ? 165 HIS H C 1 ATOM 4872 O O . HIS C 3 165 ? -79.834 -1.325 40.533 1.00 76.49 ? 165 HIS H O 1 ATOM 4873 C CB . HIS C 3 165 ? -79.244 1.462 40.350 1.00 76.19 ? 165 HIS H CB 1 ATOM 4874 C CG . HIS C 3 165 ? -78.721 2.822 40.014 1.00 76.08 ? 165 HIS H CG 1 ATOM 4875 N ND1 . HIS C 3 165 ? -78.073 3.618 40.934 1.00 76.13 ? 165 HIS H ND1 1 ATOM 4876 C CD2 . HIS C 3 165 ? -78.763 3.534 38.864 1.00 76.20 ? 165 HIS H CD2 1 ATOM 4877 C CE1 . HIS C 3 165 ? -77.729 4.758 40.362 1.00 76.31 ? 165 HIS H CE1 1 ATOM 4878 N NE2 . HIS C 3 165 ? -78.137 4.733 39.105 1.00 76.41 ? 165 HIS H NE2 1 ATOM 4879 N N . THR C 3 166 ? -78.116 -1.509 41.977 1.00 75.96 ? 166 THR H N 1 ATOM 4880 C CA . THR C 3 166 ? -78.694 -2.639 42.703 1.00 75.87 ? 166 THR H CA 1 ATOM 4881 C C . THR C 3 166 ? -79.284 -2.123 44.006 1.00 75.92 ? 166 THR H C 1 ATOM 4882 O O . THR C 3 166 ? -78.566 -1.581 44.848 1.00 76.81 ? 166 THR H O 1 ATOM 4883 C CB . THR C 3 166 ? -77.654 -3.735 43.006 1.00 76.24 ? 166 THR H CB 1 ATOM 4884 O OG1 . THR C 3 166 ? -77.155 -4.281 41.777 1.00 76.59 ? 166 THR H OG1 1 ATOM 4885 C CG2 . THR C 3 166 ? -78.282 -4.853 43.830 1.00 76.12 ? 166 THR H CG2 1 ATOM 4886 N N . PHE C 3 167 ? -80.591 -2.300 44.169 1.00 75.11 ? 167 PHE H N 1 ATOM 4887 C CA . PHE C 3 167 ? -81.317 -1.708 45.287 1.00 74.60 ? 167 PHE H CA 1 ATOM 4888 C C . PHE C 3 167 ? -81.258 -2.601 46.521 1.00 74.76 ? 167 PHE H C 1 ATOM 4889 O O . PHE C 3 167 ? -81.278 -3.826 46.396 1.00 75.07 ? 167 PHE H O 1 ATOM 4890 C CB . PHE C 3 167 ? -82.767 -1.449 44.889 1.00 73.39 ? 167 PHE H CB 1 ATOM 4891 C CG . PHE C 3 167 ? -82.905 -0.510 43.733 1.00 73.28 ? 167 PHE H CG 1 ATOM 4892 C CD1 . PHE C 3 167 ? -83.007 0.857 43.943 1.00 73.07 ? 167 PHE H CD1 1 ATOM 4893 C CD2 . PHE C 3 167 ? -82.900 -0.987 42.430 1.00 73.44 ? 167 PHE H CD2 1 ATOM 4894 C CE1 . PHE C 3 167 ? -83.117 1.729 42.877 1.00 73.09 ? 167 PHE H CE1 1 ATOM 4895 C CE2 . PHE C 3 167 ? -83.012 -0.116 41.357 1.00 73.47 ? 167 PHE H CE2 1 ATOM 4896 C CZ . PHE C 3 167 ? -83.121 1.244 41.583 1.00 73.33 ? 167 PHE H CZ 1 ATOM 4897 N N . PRO C 3 168 ? -81.165 -1.990 47.719 1.00 74.66 ? 168 PRO H N 1 ATOM 4898 C CA . PRO C 3 168 ? -81.197 -2.747 48.971 1.00 74.46 ? 168 PRO H CA 1 ATOM 4899 C C . PRO C 3 168 ? -82.418 -3.655 49.068 1.00 74.41 ? 168 PRO H C 1 ATOM 4900 O O . PRO C 3 168 ? -83.529 -3.227 48.748 1.00 73.63 ? 168 PRO H O 1 ATOM 4901 C CB . PRO C 3 168 ? -81.273 -1.652 50.038 1.00 74.04 ? 168 PRO H CB 1 ATOM 4902 C CG . PRO C 3 168 ? -80.654 -0.475 49.413 1.00 74.17 ? 168 PRO H CG 1 ATOM 4903 C CD . PRO C 3 168 ? -81.003 -0.544 47.963 1.00 74.28 ? 168 PRO H CD 1 ATOM 4904 N N . ALA C 3 169 ? -82.206 -4.897 49.497 1.00 74.94 ? 169 ALA H N 1 ATOM 4905 C CA . ALA C 3 169 ? -83.296 -5.858 49.643 1.00 75.21 ? 169 ALA H CA 1 ATOM 4906 C C . ALA C 3 169 ? -84.201 -5.453 50.799 1.00 75.71 ? 169 ALA H C 1 ATOM 4907 O O . ALA C 3 169 ? -83.762 -4.777 51.730 1.00 75.42 ? 169 ALA H O 1 ATOM 4908 C CB . ALA C 3 169 ? -82.747 -7.255 49.866 1.00 74.50 ? 169 ALA H CB 1 ATOM 4909 N N . VAL C 3 170 ? -85.467 -5.855 50.725 1.00 76.51 ? 170 VAL H N 1 ATOM 4910 C CA . VAL C 3 170 ? -86.432 -5.568 51.785 1.00 76.98 ? 170 VAL H CA 1 ATOM 4911 C C . VAL C 3 170 ? -87.198 -6.833 52.163 1.00 77.09 ? 170 VAL H C 1 ATOM 4912 O O . VAL C 3 170 ? -87.526 -7.653 51.302 1.00 76.62 ? 170 VAL H O 1 ATOM 4913 C CB . VAL C 3 170 ? -87.421 -4.455 51.374 1.00 77.47 ? 170 VAL H CB 1 ATOM 4914 C CG1 . VAL C 3 170 ? -86.676 -3.149 51.129 1.00 77.05 ? 170 VAL H CG1 1 ATOM 4915 C CG2 . VAL C 3 170 ? -88.216 -4.863 50.140 1.00 78.62 ? 170 VAL H CG2 1 ATOM 4916 N N . LEU C 3 171 ? -87.469 -6.983 53.457 1.00 77.73 ? 171 LEU H N 1 ATOM 4917 C CA . LEU C 3 171 ? -88.142 -8.165 53.980 1.00 78.40 ? 171 LEU H CA 1 ATOM 4918 C C . LEU C 3 171 ? -89.654 -7.961 53.986 1.00 79.23 ? 171 LEU H C 1 ATOM 4919 O O . LEU C 3 171 ? -90.147 -6.925 54.435 1.00 79.25 ? 171 LEU H O 1 ATOM 4920 C CB . LEU C 3 171 ? -87.650 -8.463 55.399 1.00 78.31 ? 171 LEU H CB 1 ATOM 4921 C CG . LEU C 3 171 ? -88.133 -9.764 56.049 1.00 78.29 ? 171 LEU H CG 1 ATOM 4922 C CD1 . LEU C 3 171 ? -87.632 -10.978 55.280 1.00 78.12 ? 171 LEU H CD1 1 ATOM 4923 C CD2 . LEU C 3 171 ? -87.684 -9.823 57.501 1.00 78.54 ? 171 LEU H CD2 1 ATOM 4924 N N . GLN C 3 172 ? -90.382 -8.953 53.480 1.00 80.15 ? 172 GLN H N 1 ATOM 4925 C CA . GLN C 3 172 ? -91.842 -8.940 53.505 1.00 79.95 ? 172 GLN H CA 1 ATOM 4926 C C . GLN C 3 172 ? -92.350 -10.371 53.692 1.00 80.41 ? 172 GLN H C 1 ATOM 4927 O O . GLN C 3 172 ? -92.240 -11.199 52.785 1.00 80.79 ? 172 GLN H O 1 ATOM 4928 C CB . GLN C 3 172 ? -92.393 -8.316 52.214 1.00 80.62 ? 172 GLN H CB 1 ATOM 4929 C CG . GLN C 3 172 ? -93.737 -7.588 52.373 1.00 81.21 ? 172 GLN H CG 1 ATOM 4930 C CD . GLN C 3 172 ? -94.947 -8.512 52.306 1.00 82.28 ? 172 GLN H CD 1 ATOM 4931 O OE1 . GLN C 3 172 ? -94.885 -9.608 51.747 1.00 83.10 ? 172 GLN H OE1 1 ATOM 4932 N NE2 . GLN C 3 172 ? -96.062 -8.058 52.868 1.00 82.17 ? 172 GLN H NE2 1 ATOM 4933 N N . SER C 3 173 ? -92.874 -10.654 54.885 1.00 80.43 ? 173 SER H N 1 ATOM 4934 C CA . SER C 3 173 ? -93.383 -11.982 55.247 1.00 80.28 ? 173 SER H CA 1 ATOM 4935 C C . SER C 3 173 ? -92.309 -13.070 55.142 1.00 80.49 ? 173 SER H C 1 ATOM 4936 O O . SER C 3 173 ? -92.430 -14.006 54.347 1.00 80.62 ? 173 SER H O 1 ATOM 4937 C CB . SER C 3 173 ? -94.612 -12.349 54.404 1.00 80.12 ? 173 SER H CB 1 ATOM 4938 O OG . SER C 3 173 ? -95.647 -11.397 54.575 1.00 80.12 ? 173 SER H OG 1 ATOM 4939 N N . ASP C 3 174 ? -91.253 -12.916 55.943 1.00 80.36 ? 174 ASP H N 1 ATOM 4940 C CA . ASP C 3 174 ? -90.197 -13.933 56.104 1.00 80.29 ? 174 ASP H CA 1 ATOM 4941 C C . ASP C 3 174 ? -89.365 -14.211 54.840 1.00 80.16 ? 174 ASP H C 1 ATOM 4942 O O . ASP C 3 174 ? -88.606 -15.183 54.803 1.00 80.18 ? 174 ASP H O 1 ATOM 4943 C CB . ASP C 3 174 ? -90.792 -15.252 56.630 1.00 81.53 ? 174 ASP H CB 1 ATOM 4944 C CG . ASP C 3 174 ? -91.710 -15.048 57.829 1.00 82.60 ? 174 ASP H CG 1 ATOM 4945 O OD1 . ASP C 3 174 ? -91.503 -14.073 58.583 1.00 83.32 ? 174 ASP H OD1 1 ATOM 4946 O OD2 . ASP C 3 174 ? -92.638 -15.865 58.016 1.00 82.62 ? 174 ASP H OD2 1 ATOM 4947 N N . LEU C 3 175 ? -89.492 -13.355 53.824 1.00 79.73 ? 175 LEU H N 1 ATOM 4948 C CA . LEU C 3 175 ? -88.790 -13.541 52.551 1.00 79.00 ? 175 LEU H CA 1 ATOM 4949 C C . LEU C 3 175 ? -88.314 -12.201 51.994 1.00 79.10 ? 175 LEU H C 1 ATOM 4950 O O . LEU C 3 175 ? -89.073 -11.233 51.959 1.00 79.77 ? 175 LEU H O 1 ATOM 4951 C CB . LEU C 3 175 ? -89.706 -14.228 51.535 1.00 78.23 ? 175 LEU H CB 1 ATOM 4952 C CG . LEU C 3 175 ? -89.961 -15.723 51.752 1.00 77.92 ? 175 LEU H CG 1 ATOM 4953 C CD1 . LEU C 3 175 ? -91.165 -16.192 50.948 1.00 78.06 ? 175 LEU H CD1 1 ATOM 4954 C CD2 . LEU C 3 175 ? -88.727 -16.535 51.392 1.00 77.57 ? 175 LEU H CD2 1 ATOM 4955 N N . TYR C 3 176 ? -87.058 -12.155 51.558 1.00 78.58 ? 176 TYR H N 1 ATOM 4956 C CA . TYR C 3 176 ? -86.471 -10.930 51.013 1.00 78.07 ? 176 TYR H CA 1 ATOM 4957 C C . TYR C 3 176 ? -86.851 -10.734 49.552 1.00 77.47 ? 176 TYR H C 1 ATOM 4958 O O . TYR C 3 176 ? -87.170 -11.692 48.850 1.00 77.20 ? 176 TYR H O 1 ATOM 4959 C CB . TYR C 3 176 ? -84.944 -10.950 51.153 1.00 77.10 ? 176 TYR H CB 1 ATOM 4960 C CG . TYR C 3 176 ? -84.466 -10.745 52.570 1.00 76.74 ? 176 TYR H CG 1 ATOM 4961 C CD1 . TYR C 3 176 ? -84.254 -9.467 53.074 1.00 76.82 ? 176 TYR H CD1 1 ATOM 4962 C CD2 . TYR C 3 176 ? -84.235 -11.828 53.411 1.00 76.82 ? 176 TYR H CD2 1 ATOM 4963 C CE1 . TYR C 3 176 ? -83.819 -9.271 54.378 1.00 77.04 ? 176 TYR H CE1 1 ATOM 4964 C CE2 . TYR C 3 176 ? -83.800 -11.643 54.716 1.00 77.11 ? 176 TYR H CE2 1 ATOM 4965 C CZ . TYR C 3 176 ? -83.594 -10.362 55.194 1.00 77.10 ? 176 TYR H CZ 1 ATOM 4966 O OH . TYR C 3 176 ? -83.159 -10.174 56.487 1.00 76.97 ? 176 TYR H OH 1 ATOM 4967 N N . THR C 3 177 ? -86.814 -9.482 49.107 1.00 77.82 ? 177 THR H N 1 ATOM 4968 C CA . THR C 3 177 ? -87.080 -9.139 47.713 1.00 78.10 ? 177 THR H CA 1 ATOM 4969 C C . THR C 3 177 ? -86.153 -8.011 47.275 1.00 77.87 ? 177 THR H C 1 ATOM 4970 O O . THR C 3 177 ? -86.081 -6.964 47.922 1.00 77.52 ? 177 THR H O 1 ATOM 4971 C CB . THR C 3 177 ? -88.545 -8.711 47.503 1.00 78.99 ? 177 THR H CB 1 ATOM 4972 O OG1 . THR C 3 177 ? -89.412 -9.821 47.766 1.00 79.65 ? 177 THR H OG1 1 ATOM 4973 C CG2 . THR C 3 177 ? -88.770 -8.224 46.072 1.00 78.43 ? 177 THR H CG2 1 ATOM 4974 N N . LEU C 3 178 ? -85.455 -8.237 46.169 1.00 77.89 ? 178 LEU H N 1 ATOM 4975 C CA . LEU C 3 178 ? -84.426 -7.326 45.688 1.00 77.60 ? 178 LEU H CA 1 ATOM 4976 C C . LEU C 3 178 ? -84.587 -7.121 44.189 1.00 77.46 ? 178 LEU H C 1 ATOM 4977 O O . LEU C 3 178 ? -85.155 -7.967 43.496 1.00 77.83 ? 178 LEU H O 1 ATOM 4978 C CB . LEU C 3 178 ? -83.041 -7.902 46.011 1.00 77.86 ? 178 LEU H CB 1 ATOM 4979 C CG . LEU C 3 178 ? -81.796 -7.184 45.479 1.00 77.90 ? 178 LEU H CG 1 ATOM 4980 C CD1 . LEU C 3 178 ? -80.625 -7.368 46.430 1.00 77.63 ? 178 LEU H CD1 1 ATOM 4981 C CD2 . LEU C 3 178 ? -81.435 -7.675 44.080 1.00 78.13 ? 178 LEU H CD2 1 ATOM 4982 N N . SER C 3 179 ? -84.100 -5.986 43.699 1.00 77.12 ? 179 SER H N 1 ATOM 4983 C CA . SER C 3 179 ? -84.131 -5.678 42.276 1.00 76.81 ? 179 SER H CA 1 ATOM 4984 C C . SER C 3 179 ? -82.832 -5.005 41.851 1.00 76.72 ? 179 SER H C 1 ATOM 4985 O O . SER C 3 179 ? -82.060 -4.540 42.692 1.00 77.40 ? 179 SER H O 1 ATOM 4986 C CB . SER C 3 179 ? -85.313 -4.765 41.965 1.00 77.09 ? 179 SER H CB 1 ATOM 4987 O OG . SER C 3 179 ? -85.240 -3.572 42.727 1.00 77.43 ? 179 SER H OG 1 ATOM 4988 N N . SER C 3 180 ? -82.592 -4.967 40.544 1.00 76.34 ? 180 SER H N 1 ATOM 4989 C CA . SER C 3 180 ? -81.418 -4.292 39.993 1.00 76.04 ? 180 SER H CA 1 ATOM 4990 C C . SER C 3 180 ? -81.755 -3.625 38.668 1.00 75.68 ? 180 SER H C 1 ATOM 4991 O O . SER C 3 180 ? -82.689 -4.029 37.979 1.00 75.65 ? 180 SER H O 1 ATOM 4992 C CB . SER C 3 180 ? -80.267 -5.277 39.800 1.00 75.90 ? 180 SER H CB 1 ATOM 4993 O OG . SER C 3 180 ? -79.085 -4.598 39.410 1.00 75.85 ? 180 SER H OG 1 ATOM 4994 N N . SER C 3 181 ? -80.981 -2.601 38.320 1.00 75.73 ? 181 SER H N 1 ATOM 4995 C CA . SER C 3 181 ? -81.235 -1.809 37.123 1.00 75.72 ? 181 SER H CA 1 ATOM 4996 C C . SER C 3 181 ? -79.942 -1.560 36.357 1.00 75.40 ? 181 SER H C 1 ATOM 4997 O O . SER C 3 181 ? -78.867 -1.463 36.949 1.00 75.18 ? 181 SER H O 1 ATOM 4998 C CB . SER C 3 181 ? -81.880 -0.473 37.504 1.00 75.98 ? 181 SER H CB 1 ATOM 4999 O OG . SER C 3 181 ? -82.185 0.297 36.354 1.00 76.26 ? 181 SER H OG 1 ATOM 5000 N N . VAL C 3 182 ? -80.061 -1.465 35.035 1.00 75.24 ? 182 VAL H N 1 ATOM 5001 C CA . VAL C 3 182 ? -78.921 -1.191 34.167 1.00 75.23 ? 182 VAL H CA 1 ATOM 5002 C C . VAL C 3 182 ? -79.372 -0.358 32.971 1.00 74.89 ? 182 VAL H C 1 ATOM 5003 O O . VAL C 3 182 ? -80.411 -0.633 32.369 1.00 74.54 ? 182 VAL H O 1 ATOM 5004 C CB . VAL C 3 182 ? -78.255 -2.500 33.676 1.00 75.32 ? 182 VAL H CB 1 ATOM 5005 C CG1 . VAL C 3 182 ? -79.271 -3.396 32.979 1.00 75.39 ? 182 VAL H CG1 1 ATOM 5006 C CG2 . VAL C 3 182 ? -77.077 -2.195 32.757 1.00 75.17 ? 182 VAL H CG2 1 ATOM 5007 N N . THR C 3 183 ? -78.587 0.665 32.642 1.00 74.99 ? 183 THR H N 1 ATOM 5008 C CA . THR C 3 183 ? -78.905 1.569 31.543 1.00 75.05 ? 183 THR H CA 1 ATOM 5009 C C . THR C 3 183 ? -77.788 1.547 30.504 1.00 74.81 ? 183 THR H C 1 ATOM 5010 O O . THR C 3 183 ? -76.642 1.881 30.807 1.00 74.46 ? 183 THR H O 1 ATOM 5011 C CB . THR C 3 183 ? -79.105 3.009 32.049 1.00 75.02 ? 183 THR H CB 1 ATOM 5012 O OG1 . THR C 3 183 ? -80.092 3.020 33.087 1.00 74.93 ? 183 THR H OG1 1 ATOM 5013 C CG2 . THR C 3 183 ? -79.554 3.921 30.915 1.00 75.13 ? 183 THR H CG2 1 ATOM 5014 N N . VAL C 3 184 ? -78.135 1.141 29.285 1.00 75.13 ? 184 VAL H N 1 ATOM 5015 C CA . VAL C 3 184 ? -77.187 1.076 28.172 1.00 75.23 ? 184 VAL H CA 1 ATOM 5016 C C . VAL C 3 184 ? -77.801 1.732 26.937 1.00 75.30 ? 184 VAL H C 1 ATOM 5017 O O . VAL C 3 184 ? -79.025 1.844 26.848 1.00 75.19 ? 184 VAL H O 1 ATOM 5018 C CB . VAL C 3 184 ? -76.813 -0.387 27.835 1.00 74.91 ? 184 VAL H CB 1 ATOM 5019 C CG1 . VAL C 3 184 ? -76.094 -1.035 29.007 1.00 75.02 ? 184 VAL H CG1 1 ATOM 5020 C CG2 . VAL C 3 184 ? -78.054 -1.188 27.452 1.00 74.58 ? 184 VAL H CG2 1 ATOM 5021 N N . PRO C 3 185 ? -76.956 2.173 25.982 1.00 75.52 ? 185 PRO H N 1 ATOM 5022 C CA . PRO C 3 185 ? -77.443 2.789 24.744 1.00 75.60 ? 185 PRO H CA 1 ATOM 5023 C C . PRO C 3 185 ? -78.581 2.007 24.083 1.00 75.80 ? 185 PRO H C 1 ATOM 5024 O O . PRO C 3 185 ? -78.525 0.778 24.006 1.00 75.87 ? 185 PRO H O 1 ATOM 5025 C CB . PRO C 3 185 ? -76.205 2.786 23.845 1.00 75.55 ? 185 PRO H CB 1 ATOM 5026 C CG . PRO C 3 185 ? -75.067 2.866 24.782 1.00 75.47 ? 185 PRO H CG 1 ATOM 5027 C CD . PRO C 3 185 ? -75.481 2.130 26.024 1.00 75.52 ? 185 PRO H CD 1 ATOM 5028 N N . SER C 3 186 ? -79.599 2.724 23.609 1.00 75.80 ? 186 SER H N 1 ATOM 5029 C CA . SER C 3 186 ? -80.760 2.101 22.970 1.00 75.83 ? 186 SER H CA 1 ATOM 5030 C C . SER C 3 186 ? -80.406 1.478 21.618 1.00 75.90 ? 186 SER H C 1 ATOM 5031 O O . SER C 3 186 ? -81.122 0.606 21.127 1.00 75.81 ? 186 SER H O 1 ATOM 5032 C CB . SER C 3 186 ? -81.888 3.121 22.797 1.00 75.65 ? 186 SER H CB 1 ATOM 5033 O OG . SER C 3 186 ? -81.448 4.249 22.062 1.00 75.69 ? 186 SER H OG 1 ATOM 5034 N N . SER C 3 187 ? -79.308 1.936 21.018 1.00 76.11 ? 187 SER H N 1 ATOM 5035 C CA . SER C 3 187 ? -78.793 1.347 19.782 1.00 76.42 ? 187 SER H CA 1 ATOM 5036 C C . SER C 3 187 ? -78.127 -0.012 20.027 1.00 76.62 ? 187 SER H C 1 ATOM 5037 O O . SER C 3 187 ? -78.067 -0.847 19.122 1.00 76.55 ? 187 SER H O 1 ATOM 5038 C CB . SER C 3 187 ? -77.795 2.300 19.117 1.00 76.49 ? 187 SER H CB 1 ATOM 5039 O OG . SER C 3 187 ? -76.744 2.639 20.006 1.00 76.58 ? 187 SER H OG 1 ATOM 5040 N N . THR C 3 188 ? -77.635 -0.229 21.248 1.00 76.84 ? 188 THR H N 1 ATOM 5041 C CA . THR C 3 188 ? -76.942 -1.472 21.607 1.00 76.92 ? 188 THR H CA 1 ATOM 5042 C C . THR C 3 188 ? -77.862 -2.497 22.293 1.00 77.09 ? 188 THR H C 1 ATOM 5043 O O . THR C 3 188 ? -77.386 -3.384 23.005 1.00 77.01 ? 188 THR H O 1 ATOM 5044 C CB . THR C 3 188 ? -75.734 -1.186 22.529 1.00 76.86 ? 188 THR H CB 1 ATOM 5045 O OG1 . THR C 3 188 ? -76.193 -0.669 23.785 1.00 76.81 ? 188 THR H OG1 1 ATOM 5046 C CG2 . THR C 3 188 ? -74.790 -0.182 21.881 1.00 76.80 ? 188 THR H CG2 1 ATOM 5047 N N . TRP C 3 189 ? -79.171 -2.372 22.077 1.00 77.23 ? 189 TRP H N 1 ATOM 5048 C CA . TRP C 3 189 ? -80.142 -3.335 22.603 1.00 77.28 ? 189 TRP H CA 1 ATOM 5049 C C . TRP C 3 189 ? -81.467 -3.231 21.836 1.00 77.81 ? 189 TRP H C 1 ATOM 5050 O O . TRP C 3 189 ? -81.953 -2.125 21.598 1.00 78.00 ? 189 TRP H O 1 ATOM 5051 C CB . TRP C 3 189 ? -80.383 -3.092 24.096 1.00 77.07 ? 189 TRP H CB 1 ATOM 5052 C CG . TRP C 3 189 ? -81.203 -4.163 24.750 1.00 77.07 ? 189 TRP H CG 1 ATOM 5053 C CD1 . TRP C 3 189 ? -80.743 -5.311 25.327 1.00 77.03 ? 189 TRP H CD1 1 ATOM 5054 C CD2 . TRP C 3 189 ? -82.629 -4.190 24.885 1.00 77.01 ? 189 TRP H CD2 1 ATOM 5055 N NE1 . TRP C 3 189 ? -81.793 -6.050 25.816 1.00 76.99 ? 189 TRP H NE1 1 ATOM 5056 C CE2 . TRP C 3 189 ? -82.962 -5.385 25.558 1.00 76.96 ? 189 TRP H CE2 1 ATOM 5057 C CE3 . TRP C 3 189 ? -83.657 -3.320 24.503 1.00 77.03 ? 189 TRP H CE3 1 ATOM 5058 C CZ2 . TRP C 3 189 ? -84.281 -5.732 25.859 1.00 77.01 ? 189 TRP H CZ2 1 ATOM 5059 C CZ3 . TRP C 3 189 ? -84.969 -3.666 24.803 1.00 77.06 ? 189 TRP H CZ3 1 ATOM 5060 C CH2 . TRP C 3 189 ? -85.268 -4.862 25.475 1.00 77.05 ? 189 TRP H CH2 1 ATOM 5061 N N . PRO C 3 190 ? -82.063 -4.379 21.452 1.00 78.05 ? 190 PRO H N 1 ATOM 5062 C CA . PRO C 3 190 ? -81.639 -5.759 21.687 1.00 78.33 ? 190 PRO H CA 1 ATOM 5063 C C . PRO C 3 190 ? -80.711 -6.323 20.597 1.00 78.65 ? 190 PRO H C 1 ATOM 5064 O O . PRO C 3 190 ? -80.755 -7.522 20.311 1.00 78.85 ? 190 PRO H O 1 ATOM 5065 C CB . PRO C 3 190 ? -82.970 -6.513 21.708 1.00 78.23 ? 190 PRO H CB 1 ATOM 5066 C CG . PRO C 3 190 ? -83.824 -5.771 20.733 1.00 78.16 ? 190 PRO H CG 1 ATOM 5067 C CD . PRO C 3 190 ? -83.331 -4.336 20.698 1.00 78.09 ? 190 PRO H CD 1 ATOM 5068 N N . SER C 3 191 ? -79.877 -5.469 20.004 1.00 78.65 ? 191 SER H N 1 ATOM 5069 C CA . SER C 3 191 ? -78.883 -5.912 19.025 1.00 78.52 ? 191 SER H CA 1 ATOM 5070 C C . SER C 3 191 ? -77.780 -6.731 19.698 1.00 78.48 ? 191 SER H C 1 ATOM 5071 O O . SER C 3 191 ? -77.283 -7.703 19.126 1.00 78.14 ? 191 SER H O 1 ATOM 5072 C CB . SER C 3 191 ? -78.273 -4.710 18.299 1.00 78.47 ? 191 SER H CB 1 ATOM 5073 O OG . SER C 3 191 ? -77.721 -3.783 19.219 1.00 78.51 ? 191 SER H OG 1 ATOM 5074 N N . GLU C 3 192 ? -77.403 -6.323 20.911 1.00 78.70 ? 192 GLU H N 1 ATOM 5075 C CA . GLU C 3 192 ? -76.443 -7.064 21.730 1.00 78.68 ? 192 GLU H CA 1 ATOM 5076 C C . GLU C 3 192 ? -77.145 -7.669 22.944 1.00 78.59 ? 192 GLU H C 1 ATOM 5077 O O . GLU C 3 192 ? -78.170 -7.157 23.397 1.00 78.55 ? 192 GLU H O 1 ATOM 5078 C CB . GLU C 3 192 ? -75.309 -6.144 22.184 1.00 78.79 ? 192 GLU H CB 1 ATOM 5079 C CG . GLU C 3 192 ? -74.476 -5.580 21.038 1.00 78.82 ? 192 GLU H CG 1 ATOM 5080 C CD . GLU C 3 192 ? -73.325 -4.708 21.513 1.00 78.74 ? 192 GLU H CD 1 ATOM 5081 O OE1 . GLU C 3 192 ? -72.265 -4.714 20.851 1.00 78.66 ? 192 GLU H OE1 1 ATOM 5082 O OE2 . GLU C 3 192 ? -73.477 -4.017 22.543 1.00 78.71 ? 192 GLU H OE2 1 ATOM 5083 N N . THR C 3 193 ? -76.581 -8.755 23.467 1.00 78.59 ? 193 THR H N 1 ATOM 5084 C CA . THR C 3 193 ? -77.203 -9.506 24.557 1.00 78.77 ? 193 THR H CA 1 ATOM 5085 C C . THR C 3 193 ? -77.000 -8.821 25.908 1.00 78.97 ? 193 THR H C 1 ATOM 5086 O O . THR C 3 193 ? -75.964 -8.201 26.151 1.00 79.01 ? 193 THR H O 1 ATOM 5087 C CB . THR C 3 193 ? -76.636 -10.939 24.645 1.00 78.52 ? 193 THR H CB 1 ATOM 5088 O OG1 . THR C 3 193 ? -76.601 -11.525 23.338 1.00 78.49 ? 193 THR H OG1 1 ATOM 5089 C CG2 . THR C 3 193 ? -77.491 -11.802 25.564 1.00 78.47 ? 193 THR H CG2 1 ATOM 5090 N N . VAL C 3 194 ? -78.005 -8.939 26.775 1.00 79.16 ? 194 VAL H N 1 ATOM 5091 C CA . VAL C 3 194 ? -77.921 -8.462 28.154 1.00 79.26 ? 194 VAL H CA 1 ATOM 5092 C C . VAL C 3 194 ? -78.541 -9.505 29.087 1.00 79.61 ? 194 VAL H C 1 ATOM 5093 O O . VAL C 3 194 ? -79.750 -9.747 29.041 1.00 79.77 ? 194 VAL H O 1 ATOM 5094 C CB . VAL C 3 194 ? -78.650 -7.113 28.334 1.00 79.08 ? 194 VAL H CB 1 ATOM 5095 C CG1 . VAL C 3 194 ? -78.615 -6.676 29.793 1.00 79.02 ? 194 VAL H CG1 1 ATOM 5096 C CG2 . VAL C 3 194 ? -78.028 -6.050 27.445 1.00 78.94 ? 194 VAL H CG2 1 ATOM 5097 N N . THR C 3 195 ? -77.707 -10.118 29.926 1.00 79.69 ? 195 THR H N 1 ATOM 5098 C CA . THR C 3 195 ? -78.148 -11.169 30.841 1.00 79.63 ? 195 THR H CA 1 ATOM 5099 C C . THR C 3 195 ? -77.933 -10.742 32.292 1.00 79.94 ? 195 THR H C 1 ATOM 5100 O O . THR C 3 195 ? -76.899 -10.160 32.626 1.00 79.92 ? 195 THR H O 1 ATOM 5101 C CB . THR C 3 195 ? -77.380 -12.484 30.590 1.00 79.80 ? 195 THR H CB 1 ATOM 5102 O OG1 . THR C 3 195 ? -77.421 -12.810 29.195 1.00 79.83 ? 195 THR H OG1 1 ATOM 5103 C CG2 . THR C 3 195 ? -77.987 -13.625 31.395 1.00 79.84 ? 195 THR H CG2 1 ATOM 5104 N N . CYS C 3 196 ? -78.914 -11.037 33.144 1.00 80.31 ? 196 CYS H N 1 ATOM 5105 C CA . CYS C 3 196 ? -78.816 -10.757 34.577 1.00 79.56 ? 196 CYS H CA 1 ATOM 5106 C C . CYS C 3 196 ? -78.246 -11.971 35.306 1.00 79.08 ? 196 CYS H C 1 ATOM 5107 O O . CYS C 3 196 ? -78.876 -13.027 35.341 1.00 79.12 ? 196 CYS H O 1 ATOM 5108 C CB . CYS C 3 196 ? -80.192 -10.409 35.153 1.00 80.20 ? 196 CYS H CB 1 ATOM 5109 S SG . CYS C 3 196 ? -80.156 -10.005 36.918 1.00 81.33 ? 196 CYS H SG 1 ATOM 5110 N N . ASN C 3 197 ? -77.059 -11.810 35.890 1.00 78.89 ? 197 ASN H N 1 ATOM 5111 C CA . ASN C 3 197 ? -76.364 -12.906 36.575 1.00 78.82 ? 197 ASN H CA 1 ATOM 5112 C C . ASN C 3 197 ? -76.546 -12.842 38.095 1.00 78.79 ? 197 ASN H C 1 ATOM 5113 O O . ASN C 3 197 ? -75.760 -12.204 38.799 1.00 78.91 ? 197 ASN H O 1 ATOM 5114 C CB . ASN C 3 197 ? -74.869 -12.894 36.225 1.00 78.75 ? 197 ASN H CB 1 ATOM 5115 C CG . ASN C 3 197 ? -74.596 -13.319 34.789 1.00 78.76 ? 197 ASN H CG 1 ATOM 5116 O OD1 . ASN C 3 197 ? -73.782 -14.210 34.538 1.00 78.59 ? 197 ASN H OD1 1 ATOM 5117 N ND2 . ASN C 3 197 ? -75.272 -12.681 33.839 1.00 78.78 ? 197 ASN H ND2 1 ATOM 5118 N N . VAL C 3 198 ? -77.585 -13.513 38.589 1.00 78.54 ? 198 VAL H N 1 ATOM 5119 C CA . VAL C 3 198 ? -77.898 -13.546 40.019 1.00 78.12 ? 198 VAL H CA 1 ATOM 5120 C C . VAL C 3 198 ? -77.254 -14.766 40.685 1.00 78.04 ? 198 VAL H C 1 ATOM 5121 O O . VAL C 3 198 ? -77.097 -15.815 40.055 1.00 78.05 ? 198 VAL H O 1 ATOM 5122 C CB . VAL C 3 198 ? -79.424 -13.596 40.250 1.00 77.46 ? 198 VAL H CB 1 ATOM 5123 C CG1 . VAL C 3 198 ? -79.751 -13.550 41.738 1.00 76.94 ? 198 VAL H CG1 1 ATOM 5124 C CG2 . VAL C 3 198 ? -80.108 -12.454 39.515 1.00 77.36 ? 198 VAL H CG2 1 ATOM 5125 N N . ALA C 3 199 ? -76.887 -14.619 41.957 1.00 77.90 ? 199 ALA H N 1 ATOM 5126 C CA . ALA C 3 199 ? -76.272 -15.703 42.724 1.00 77.98 ? 199 ALA H CA 1 ATOM 5127 C C . ALA C 3 199 ? -76.717 -15.666 44.186 1.00 78.11 ? 199 ALA H C 1 ATOM 5128 O O . ALA C 3 199 ? -76.623 -14.628 44.843 1.00 78.32 ? 199 ALA H O 1 ATOM 5129 C CB . ALA C 3 199 ? -74.761 -15.612 42.635 1.00 78.06 ? 199 ALA H CB 1 ATOM 5130 N N . HIS C 3 200 ? -77.196 -16.806 44.685 1.00 77.91 ? 200 HIS H N 1 ATOM 5131 C CA . HIS C 3 200 ? -77.629 -16.941 46.078 1.00 78.02 ? 200 HIS H CA 1 ATOM 5132 C C . HIS C 3 200 ? -76.883 -18.112 46.734 1.00 78.03 ? 200 HIS H C 1 ATOM 5133 O O . HIS C 3 200 ? -77.367 -19.244 46.714 1.00 78.13 ? 200 HIS H O 1 ATOM 5134 C CB . HIS C 3 200 ? -79.146 -17.156 46.140 1.00 77.66 ? 200 HIS H CB 1 ATOM 5135 C CG . HIS C 3 200 ? -79.702 -17.160 47.531 1.00 77.48 ? 200 HIS H CG 1 ATOM 5136 N ND1 . HIS C 3 200 ? -80.406 -18.225 48.048 1.00 77.37 ? 200 HIS H ND1 1 ATOM 5137 C CD2 . HIS C 3 200 ? -79.656 -16.228 48.512 1.00 77.17 ? 200 HIS H CD2 1 ATOM 5138 C CE1 . HIS C 3 200 ? -80.773 -17.948 49.287 1.00 77.23 ? 200 HIS H CE1 1 ATOM 5139 N NE2 . HIS C 3 200 ? -80.329 -16.743 49.593 1.00 77.00 ? 200 HIS H NE2 1 ATOM 5140 N N . PRO C 3 201 ? -75.692 -17.838 47.307 1.00 78.33 ? 201 PRO H N 1 ATOM 5141 C CA . PRO C 3 201 ? -74.789 -18.852 47.877 1.00 78.41 ? 201 PRO H CA 1 ATOM 5142 C C . PRO C 3 201 ? -75.433 -19.847 48.847 1.00 78.65 ? 201 PRO H C 1 ATOM 5143 O O . PRO C 3 201 ? -75.072 -21.027 48.840 1.00 78.81 ? 201 PRO H O 1 ATOM 5144 C CB . PRO C 3 201 ? -73.745 -18.010 48.618 1.00 78.78 ? 201 PRO H CB 1 ATOM 5145 C CG . PRO C 3 201 ? -73.717 -16.727 47.900 1.00 78.93 ? 201 PRO H CG 1 ATOM 5146 C CD . PRO C 3 201 ? -75.118 -16.483 47.418 1.00 78.83 ? 201 PRO H CD 1 ATOM 5147 N N . ALA C 3 202 ? -76.366 -19.375 49.673 1.00 78.49 ? 202 ALA H N 1 ATOM 5148 C CA . ALA C 3 202 ? -77.001 -20.220 50.691 1.00 78.37 ? 202 ALA H CA 1 ATOM 5149 C C . ALA C 3 202 ? -77.801 -21.373 50.083 1.00 77.85 ? 202 ALA H C 1 ATOM 5150 O O . ALA C 3 202 ? -77.840 -22.466 50.645 1.00 77.64 ? 202 ALA H O 1 ATOM 5151 C CB . ALA C 3 202 ? -77.895 -19.380 51.593 1.00 78.44 ? 202 ALA H CB 1 ATOM 5152 N N . SER C 3 203 ? -78.435 -21.120 48.941 1.00 78.12 ? 203 SER H N 1 ATOM 5153 C CA . SER C 3 203 ? -79.222 -22.136 48.241 1.00 78.69 ? 203 SER H CA 1 ATOM 5154 C C . SER C 3 203 ? -78.450 -22.778 47.082 1.00 79.00 ? 203 SER H C 1 ATOM 5155 O O . SER C 3 203 ? -78.973 -23.669 46.410 1.00 79.13 ? 203 SER H O 1 ATOM 5156 C CB . SER C 3 203 ? -80.517 -21.515 47.711 1.00 78.34 ? 203 SER H CB 1 ATOM 5157 O OG . SER C 3 203 ? -80.243 -20.468 46.797 1.00 78.02 ? 203 SER H OG 1 ATOM 5158 N N . SER C 3 204 ? -77.214 -22.326 46.861 1.00 79.16 ? 204 SER H N 1 ATOM 5159 C CA . SER C 3 204 ? -76.384 -22.779 45.736 1.00 79.78 ? 204 SER H CA 1 ATOM 5160 C C . SER C 3 204 ? -77.063 -22.519 44.386 1.00 80.23 ? 204 SER H C 1 ATOM 5161 O O . SER C 3 204 ? -77.056 -23.377 43.499 1.00 80.42 ? 204 SER H O 1 ATOM 5162 C CB . SER C 3 204 ? -76.023 -24.265 45.881 1.00 79.98 ? 204 SER H CB 1 ATOM 5163 O OG . SER C 3 204 ? -75.458 -24.535 47.152 1.00 80.06 ? 204 SER H OG 1 ATOM 5164 N N . THR C 3 205 ? -77.642 -21.329 44.243 1.00 80.61 ? 205 THR H N 1 ATOM 5165 C CA . THR C 3 205 ? -78.352 -20.943 43.025 1.00 80.81 ? 205 THR H CA 1 ATOM 5166 C C . THR C 3 205 ? -77.484 -20.023 42.171 1.00 81.11 ? 205 THR H C 1 ATOM 5167 O O . THR C 3 205 ? -76.733 -19.199 42.697 1.00 81.12 ? 205 THR H O 1 ATOM 5168 C CB . THR C 3 205 ? -79.675 -20.219 43.358 1.00 81.27 ? 205 THR H CB 1 ATOM 5169 O OG1 . THR C 3 205 ? -80.494 -21.065 44.174 1.00 81.77 ? 205 THR H OG1 1 ATOM 5170 C CG2 . THR C 3 205 ? -80.437 -19.857 42.085 1.00 81.00 ? 205 THR H CG2 1 ATOM 5171 N N . LYS C 3 206 ? -77.593 -20.174 40.853 1.00 81.33 ? 206 LYS H N 1 ATOM 5172 C CA . LYS C 3 206 ? -76.845 -19.350 39.908 1.00 81.34 ? 206 LYS H CA 1 ATOM 5173 C C . LYS C 3 206 ? -77.612 -19.253 38.587 1.00 81.35 ? 206 LYS H C 1 ATOM 5174 O O . LYS C 3 206 ? -77.320 -19.970 37.627 1.00 81.38 ? 206 LYS H O 1 ATOM 5175 C CB . LYS C 3 206 ? -75.444 -19.933 39.690 1.00 81.40 ? 206 LYS H CB 1 ATOM 5176 C CG . LYS C 3 206 ? -74.510 -19.049 38.874 1.00 81.36 ? 206 LYS H CG 1 ATOM 5177 C CD . LYS C 3 206 ? -73.085 -19.584 38.897 1.00 81.35 ? 206 LYS H CD 1 ATOM 5178 C CE . LYS C 3 206 ? -72.142 -18.704 38.093 1.00 81.27 ? 206 LYS H CE 1 ATOM 5179 N NZ . LYS C 3 206 ? -70.723 -19.129 38.239 1.00 81.18 ? 206 LYS H NZ 1 ATOM 5180 N N . VAL C 3 207 ? -78.601 -18.363 38.558 1.00 81.39 ? 207 VAL H N 1 ATOM 5181 C CA . VAL C 3 207 ? -79.476 -18.203 37.397 1.00 81.68 ? 207 VAL H CA 1 ATOM 5182 C C . VAL C 3 207 ? -78.957 -17.103 36.474 1.00 81.23 ? 207 VAL H C 1 ATOM 5183 O O . VAL C 3 207 ? -78.359 -16.129 36.932 1.00 80.84 ? 207 VAL H O 1 ATOM 5184 C CB . VAL C 3 207 ? -80.922 -17.863 37.830 1.00 82.50 ? 207 VAL H CB 1 ATOM 5185 C CG1 . VAL C 3 207 ? -81.843 -17.783 36.619 1.00 82.68 ? 207 VAL H CG1 1 ATOM 5186 C CG2 . VAL C 3 207 ? -81.437 -18.896 38.824 1.00 82.74 ? 207 VAL H CG2 1 ATOM 5187 N N . ASP C 3 208 ? -79.186 -17.277 35.173 1.00 81.47 ? 208 ASP H N 1 ATOM 5188 C CA . ASP C 3 208 ? -78.796 -16.298 34.159 1.00 81.73 ? 208 ASP H CA 1 ATOM 5189 C C . ASP C 3 208 ? -79.979 -16.019 33.231 1.00 81.78 ? 208 ASP H C 1 ATOM 5190 O O . ASP C 3 208 ? -80.228 -16.774 32.287 1.00 81.93 ? 208 ASP H O 1 ATOM 5191 C CB . ASP C 3 208 ? -77.605 -16.818 33.346 1.00 81.77 ? 208 ASP H CB 1 ATOM 5192 C CG . ASP C 3 208 ? -76.372 -17.064 34.201 1.00 81.84 ? 208 ASP H CG 1 ATOM 5193 O OD1 . ASP C 3 208 ? -76.054 -16.212 35.058 1.00 81.91 ? 208 ASP H OD1 1 ATOM 5194 O OD2 . ASP C 3 208 ? -75.714 -18.108 34.009 1.00 81.92 ? 208 ASP H OD2 1 ATOM 5195 N N . LYS C 3 209 ? -80.704 -14.935 33.506 1.00 81.62 ? 209 LYS H N 1 ATOM 5196 C CA . LYS C 3 209 ? -81.901 -14.585 32.736 1.00 81.94 ? 209 LYS H CA 1 ATOM 5197 C C . LYS C 3 209 ? -81.607 -13.511 31.692 1.00 81.85 ? 209 LYS H C 1 ATOM 5198 O O . LYS C 3 209 ? -81.194 -12.401 32.030 1.00 81.70 ? 209 LYS H O 1 ATOM 5199 C CB . LYS C 3 209 ? -83.019 -14.107 33.670 1.00 82.14 ? 209 LYS H CB 1 ATOM 5200 C CG . LYS C 3 209 ? -83.603 -15.200 34.562 1.00 82.39 ? 209 LYS H CG 1 ATOM 5201 C CD . LYS C 3 209 ? -84.470 -16.182 33.776 1.00 82.32 ? 209 LYS H CD 1 ATOM 5202 C CE . LYS C 3 209 ? -85.028 -17.279 34.672 1.00 82.19 ? 209 LYS H CE 1 ATOM 5203 N NZ . LYS C 3 209 ? -85.801 -18.294 33.904 1.00 82.35 ? 209 LYS H NZ 1 ATOM 5204 N N . LYS C 3 210 ? -81.825 -13.854 30.423 1.00 82.11 ? 210 LYS H N 1 ATOM 5205 C CA . LYS C 3 210 ? -81.679 -12.907 29.320 1.00 82.39 ? 210 LYS H CA 1 ATOM 5206 C C . LYS C 3 210 ? -82.924 -12.034 29.216 1.00 82.53 ? 210 LYS H C 1 ATOM 5207 O O . LYS C 3 210 ? -84.047 -12.524 29.352 1.00 82.42 ? 210 LYS H O 1 ATOM 5208 C CB . LYS C 3 210 ? -81.457 -13.652 28.001 1.00 82.08 ? 210 LYS H CB 1 ATOM 5209 C CG . LYS C 3 210 ? -80.120 -14.370 27.910 1.00 82.00 ? 210 LYS H CG 1 ATOM 5210 C CD . LYS C 3 210 ? -80.145 -15.465 26.855 1.00 82.08 ? 210 LYS H CD 1 ATOM 5211 C CE . LYS C 3 210 ? -78.757 -16.028 26.603 1.00 82.04 ? 210 LYS H CE 1 ATOM 5212 N NZ . LYS C 3 210 ? -77.945 -15.141 25.726 1.00 82.06 ? 210 LYS H NZ 1 ATOM 5213 N N . ILE C 3 211 ? -82.720 -10.744 28.964 1.00 82.94 ? 211 ILE H N 1 ATOM 5214 C CA . ILE C 3 211 ? -83.822 -9.788 28.891 1.00 83.88 ? 211 ILE H CA 1 ATOM 5215 C C . ILE C 3 211 ? -84.395 -9.758 27.472 1.00 84.56 ? 211 ILE H C 1 ATOM 5216 O O . ILE C 3 211 ? -83.808 -9.160 26.568 1.00 84.27 ? 211 ILE H O 1 ATOM 5217 C CB . ILE C 3 211 ? -83.373 -8.364 29.306 1.00 83.08 ? 211 ILE H CB 1 ATOM 5218 C CG1 . ILE C 3 211 ? -82.647 -8.388 30.657 1.00 82.67 ? 211 ILE H CG1 1 ATOM 5219 C CG2 . ILE C 3 211 ? -84.569 -7.431 29.383 1.00 82.85 ? 211 ILE H CG2 1 ATOM 5220 C CD1 . ILE C 3 211 ? -83.462 -8.981 31.786 1.00 82.52 ? 211 ILE H CD1 1 ATOM 5221 N N . VAL C 3 212 ? -85.538 -10.416 27.286 1.00 85.69 ? 212 VAL H N 1 ATOM 5222 C CA . VAL C 3 212 ? -86.188 -10.498 25.975 1.00 86.68 ? 212 VAL H CA 1 ATOM 5223 C C . VAL C 3 212 ? -87.066 -9.262 25.728 1.00 87.73 ? 212 VAL H C 1 ATOM 5224 O O . VAL C 3 212 ? -87.739 -8.791 26.647 1.00 87.71 ? 212 VAL H O 1 ATOM 5225 C CB . VAL C 3 212 ? -87.048 -11.788 25.845 1.00 86.27 ? 212 VAL H CB 1 ATOM 5226 C CG1 . VAL C 3 212 ? -88.198 -11.786 26.851 1.00 86.31 ? 212 VAL H CG1 1 ATOM 5227 C CG2 . VAL C 3 212 ? -87.576 -11.944 24.426 1.00 85.90 ? 212 VAL H CG2 1 ATOM 5228 N N . PRO C 3 213 ? -87.045 -8.718 24.492 1.00 88.97 ? 213 PRO H N 1 ATOM 5229 C CA . PRO C 3 213 ? -87.939 -7.605 24.149 1.00 90.01 ? 213 PRO H CA 1 ATOM 5230 C C . PRO C 3 213 ? -89.423 -7.959 24.284 1.00 91.53 ? 213 PRO H C 1 ATOM 5231 O O . PRO C 3 213 ? -89.850 -9.025 23.835 1.00 91.42 ? 213 PRO H O 1 ATOM 5232 C CB . PRO C 3 213 ? -87.595 -7.311 22.681 1.00 89.58 ? 213 PRO H CB 1 ATOM 5233 C CG . PRO C 3 213 ? -86.243 -7.876 22.480 1.00 89.30 ? 213 PRO H CG 1 ATOM 5234 C CD . PRO C 3 213 ? -86.168 -9.076 23.361 1.00 89.12 ? 213 PRO H CD 1 ATOM 5235 N N . ARG C 3 214 ? -90.191 -7.060 24.899 1.00 93.14 ? 214 ARG H N 1 ATOM 5236 C CA . ARG C 3 214 ? -91.621 -7.268 25.132 1.00 93.45 ? 214 ARG H CA 1 ATOM 5237 C C . ARG C 3 214 ? -92.414 -6.032 24.709 1.00 94.51 ? 214 ARG H C 1 ATOM 5238 O O . ARG C 3 214 ? -92.551 -5.746 23.519 1.00 95.03 ? 214 ARG H O 1 ATOM 5239 C CB . ARG C 3 214 ? -91.874 -7.570 26.613 1.00 94.14 ? 214 ARG H CB 1 ATOM 5240 C CG . ARG C 3 214 ? -93.269 -8.105 26.925 1.00 93.98 ? 214 ARG H CG 1 ATOM 5241 C CD . ARG C 3 214 ? -93.485 -8.226 28.431 1.00 94.42 ? 214 ARG H CD 1 ATOM 5242 N NE . ARG C 3 214 ? -94.775 -8.831 28.769 1.00 94.80 ? 214 ARG H NE 1 ATOM 5243 C CZ . ARG C 3 214 ? -95.951 -8.201 28.735 1.00 95.31 ? 214 ARG H CZ 1 ATOM 5244 N NH1 . ARG C 3 214 ? -96.037 -6.924 28.365 1.00 95.31 ? 214 ARG H NH1 1 ATOM 5245 N NH2 . ARG C 3 214 ? -97.057 -8.859 29.069 1.00 95.29 ? 214 ARG H NH2 1 HETATM 5246 C C1 . NAG D 4 . ? -60.182 -37.128 -2.764 1.00 81.61 ? 1240 NAG A C1 1 HETATM 5247 C C2 . NAG D 4 . ? -60.399 -37.144 -4.281 1.00 83.02 ? 1240 NAG A C2 1 HETATM 5248 C C3 . NAG D 4 . ? -61.777 -36.612 -4.660 1.00 82.81 ? 1240 NAG A C3 1 HETATM 5249 C C4 . NAG D 4 . ? -62.869 -37.320 -3.869 1.00 83.24 ? 1240 NAG A C4 1 HETATM 5250 C C5 . NAG D 4 . ? -62.552 -37.299 -2.375 1.00 82.46 ? 1240 NAG A C5 1 HETATM 5251 C C6 . NAG D 4 . ? -63.538 -38.164 -1.594 1.00 81.93 ? 1240 NAG A C6 1 HETATM 5252 C C7 . NAG D 4 . ? -58.746 -36.783 -6.053 1.00 83.68 ? 1240 NAG A C7 1 HETATM 5253 C C8 . NAG D 4 . ? -57.727 -35.848 -6.636 1.00 83.49 ? 1240 NAG A C8 1 HETATM 5254 N N2 . NAG D 4 . ? -59.383 -36.356 -4.961 1.00 83.71 ? 1240 NAG A N2 1 HETATM 5255 O O3 . NAG D 4 . ? -61.991 -36.816 -6.039 1.00 82.27 ? 1240 NAG A O3 1 HETATM 5256 O O4 . NAG D 4 . ? -64.106 -36.681 -4.104 1.00 83.78 ? 1240 NAG A O4 1 HETATM 5257 O O5 . NAG D 4 . ? -61.255 -37.803 -2.134 1.00 82.04 ? 1240 NAG A O5 1 HETATM 5258 O O6 . NAG D 4 . ? -63.300 -39.529 -1.891 1.00 80.92 ? 1240 NAG A O6 1 HETATM 5259 O O7 . NAG D 4 . ? -58.952 -37.876 -6.581 1.00 83.70 ? 1240 NAG A O7 1 HETATM 5260 C C1 . FUC E 5 . ? -64.479 -40.316 -1.615 1.00 80.09 ? 1241 FUC A C1 1 HETATM 5261 C C2 . FUC E 5 . ? -64.311 -41.718 -2.195 1.00 79.86 ? 1241 FUC A C2 1 HETATM 5262 C C3 . FUC E 5 . ? -63.293 -42.530 -1.404 1.00 79.20 ? 1241 FUC A C3 1 HETATM 5263 C C4 . FUC E 5 . ? -63.591 -42.456 0.091 1.00 79.45 ? 1241 FUC A C4 1 HETATM 5264 C C5 . FUC E 5 . ? -63.767 -41.012 0.544 1.00 79.05 ? 1241 FUC A C5 1 HETATM 5265 C C6 . FUC E 5 . ? -64.159 -40.947 2.016 1.00 78.21 ? 1241 FUC A C6 1 HETATM 5266 O O2 . FUC E 5 . ? -63.903 -41.626 -3.543 1.00 80.15 ? 1241 FUC A O2 1 HETATM 5267 O O3 . FUC E 5 . ? -63.321 -43.874 -1.828 1.00 78.64 ? 1241 FUC A O3 1 HETATM 5268 O O4 . FUC E 5 . ? -64.768 -43.177 0.378 1.00 79.82 ? 1241 FUC A O4 1 HETATM 5269 O O5 . FUC E 5 . ? -64.776 -40.400 -0.234 1.00 79.48 ? 1241 FUC A O5 1 HETATM 5270 C C1 . NAG F 4 . ? -42.834 -30.257 -16.979 1.00 92.26 ? 1269 NAG A C1 1 HETATM 5271 C C2 . NAG F 4 . ? -42.331 -30.219 -18.435 1.00 95.16 ? 1269 NAG A C2 1 HETATM 5272 C C3 . NAG F 4 . ? -43.429 -29.978 -19.482 1.00 95.62 ? 1269 NAG A C3 1 HETATM 5273 C C4 . NAG F 4 . ? -44.789 -30.567 -19.115 1.00 95.90 ? 1269 NAG A C4 1 HETATM 5274 C C5 . NAG F 4 . ? -45.096 -30.342 -17.638 1.00 95.82 ? 1269 NAG A C5 1 HETATM 5275 C C6 . NAG F 4 . ? -46.447 -30.931 -17.227 1.00 96.83 ? 1269 NAG A C6 1 HETATM 5276 C C7 . NAG F 4 . ? -40.010 -29.403 -18.302 1.00 97.06 ? 1269 NAG A C7 1 HETATM 5277 C C8 . NAG F 4 . ? -39.088 -28.234 -18.510 1.00 96.33 ? 1269 NAG A C8 1 HETATM 5278 N N2 . NAG F 4 . ? -41.301 -29.195 -18.581 1.00 96.17 ? 1269 NAG A N2 1 HETATM 5279 O O3 . NAG F 4 . ? -43.011 -30.516 -20.719 1.00 95.70 ? 1269 NAG A O3 1 HETATM 5280 O O4 . NAG F 4 . ? -45.781 -29.953 -19.910 1.00 95.95 ? 1269 NAG A O4 1 HETATM 5281 O O5 . NAG F 4 . ? -44.068 -30.946 -16.885 1.00 94.04 ? 1269 NAG A O5 1 HETATM 5282 O O6 . NAG F 4 . ? -46.469 -32.321 -17.468 1.00 97.46 ? 1269 NAG A O6 1 HETATM 5283 O O7 . NAG F 4 . ? -39.558 -30.476 -17.894 1.00 97.77 ? 1269 NAG A O7 1 HETATM 5284 C C1 . NAG G 4 . ? -47.122 -9.372 35.807 1.00 86.14 ? 1358 NAG A C1 1 HETATM 5285 C C2 . NAG G 4 . ? -48.238 -9.299 36.857 1.00 88.51 ? 1358 NAG A C2 1 HETATM 5286 C C3 . NAG G 4 . ? -49.239 -10.455 36.786 1.00 88.95 ? 1358 NAG A C3 1 HETATM 5287 C C4 . NAG G 4 . ? -49.601 -10.814 35.350 1.00 89.20 ? 1358 NAG A C4 1 HETATM 5288 C C5 . NAG G 4 . ? -48.340 -10.933 34.506 1.00 88.84 ? 1358 NAG A C5 1 HETATM 5289 C C6 . NAG G 4 . ? -48.683 -11.274 33.062 1.00 89.34 ? 1358 NAG A C6 1 HETATM 5290 C C7 . NAG G 4 . ? -47.387 -8.081 38.810 1.00 90.13 ? 1358 NAG A C7 1 HETATM 5291 C C8 . NAG G 4 . ? -46.791 -8.196 40.183 1.00 89.30 ? 1358 NAG A C8 1 HETATM 5292 N N2 . NAG G 4 . ? -47.660 -9.232 38.191 1.00 89.65 ? 1358 NAG A N2 1 HETATM 5293 O O3 . NAG G 4 . ? -50.414 -10.114 37.493 1.00 88.86 ? 1358 NAG A O3 1 HETATM 5294 O O4 . NAG G 4 . ? -50.309 -12.036 35.332 1.00 89.37 ? 1358 NAG A O4 1 HETATM 5295 O O5 . NAG G 4 . ? -47.656 -9.701 34.540 1.00 87.71 ? 1358 NAG A O5 1 HETATM 5296 O O6 . NAG G 4 . ? -49.028 -12.638 32.981 1.00 89.97 ? 1358 NAG A O6 1 HETATM 5297 O O7 . NAG G 4 . ? -47.598 -6.971 38.317 1.00 90.74 ? 1358 NAG A O7 1 HETATM 5298 S S . SO4 H 6 . ? -33.199 -8.701 81.261 0.50 111.45 ? 2000 SO4 A S 1 HETATM 5299 O O1 . SO4 H 6 . ? -32.305 -7.561 81.442 0.50 111.13 ? 2000 SO4 A O1 1 HETATM 5300 O O2 . SO4 H 6 . ? -34.585 -8.249 81.329 0.50 111.42 ? 2000 SO4 A O2 1 HETATM 5301 O O3 . SO4 H 6 . ? -32.951 -9.308 79.956 0.50 111.54 ? 2000 SO4 A O3 1 HETATM 5302 O O4 . SO4 H 6 . ? -32.953 -9.686 82.310 0.50 111.55 ? 2000 SO4 A O4 1 HETATM 5303 S S . SO4 I 6 . ? -60.096 8.355 49.407 1.00 86.48 ? 2000 SO4 L S 1 HETATM 5304 O O1 . SO4 I 6 . ? -58.642 8.266 49.499 1.00 86.46 ? 2000 SO4 L O1 1 HETATM 5305 O O2 . SO4 I 6 . ? -60.471 9.335 48.391 1.00 86.54 ? 2000 SO4 L O2 1 HETATM 5306 O O3 . SO4 I 6 . ? -60.631 7.049 49.036 1.00 86.15 ? 2000 SO4 L O3 1 HETATM 5307 O O4 . SO4 I 6 . ? -60.636 8.771 50.698 1.00 86.59 ? 2000 SO4 L O4 1 HETATM 5308 ZN ZN . ZN J 7 . ? -68.431 2.479 82.411 1.00 79.58 ? 2001 ZN L ZN 1 HETATM 5309 ZN ZN . ZN K 7 . ? -109.752 -5.659 40.654 0.50 99.62 ? 2002 ZN L ZN 1 HETATM 5310 C C . TRS L 8 . ? -54.176 13.320 48.336 1.00 101.49 ? 2003 TRS L C 1 HETATM 5311 C C1 . TRS L 8 . ? -55.102 12.552 47.386 1.00 101.62 ? 2003 TRS L C1 1 HETATM 5312 C C2 . TRS L 8 . ? -53.378 12.535 49.388 1.00 101.63 ? 2003 TRS L C2 1 HETATM 5313 C C3 . TRS L 8 . ? -54.172 14.890 48.307 1.00 101.30 ? 2003 TRS L C3 1 HETATM 5314 N N . TRS L 8 . ? -55.312 13.394 49.304 1.00 101.23 ? 2003 TRS L N 1 HETATM 5315 O O1 . TRS L 8 . ? -54.362 12.136 46.231 1.00 101.70 ? 2003 TRS L O1 1 HETATM 5316 O O2 . TRS L 8 . ? -53.192 13.291 50.592 1.00 102.03 ? 2003 TRS L O2 1 HETATM 5317 O O3 . TRS L 8 . ? -53.622 15.438 49.512 1.00 101.15 ? 2003 TRS L O3 1 HETATM 5318 C C . TRS M 8 . ? -78.248 6.366 53.005 1.00 92.37 ? 2004 TRS L C 1 HETATM 5319 C C1 . TRS M 8 . ? -78.966 7.670 53.361 1.00 91.42 ? 2004 TRS L C1 1 HETATM 5320 C C2 . TRS M 8 . ? -78.381 5.357 54.144 1.00 92.70 ? 2004 TRS L C2 1 HETATM 5321 C C3 . TRS M 8 . ? -76.770 6.593 52.684 1.00 91.96 ? 2004 TRS L C3 1 HETATM 5322 N N . TRS M 8 . ? -78.920 5.799 51.805 1.00 93.14 ? 2004 TRS L N 1 HETATM 5323 O O1 . TRS M 8 . ? -78.301 8.810 52.797 1.00 90.59 ? 2004 TRS L O1 1 HETATM 5324 O O2 . TRS M 8 . ? -77.973 4.053 53.709 1.00 92.89 ? 2004 TRS L O2 1 HETATM 5325 O O3 . TRS M 8 . ? -76.626 7.111 51.358 1.00 91.91 ? 2004 TRS L O3 1 HETATM 5326 O O . HOH N 9 . ? -53.407 1.891 78.197 1.00 59.19 ? 3001 HOH A O 1 HETATM 5327 O O . HOH N 9 . ? -50.295 -40.124 -4.341 1.00 67.15 ? 3002 HOH A O 1 HETATM 5328 O O . HOH N 9 . ? -46.668 -10.211 25.253 1.00 65.35 ? 3003 HOH A O 1 HETATM 5329 O O . HOH N 9 . ? -47.102 -0.258 46.887 1.00 81.92 ? 3004 HOH A O 1 HETATM 5330 O O . HOH N 9 . ? -45.753 1.834 44.967 1.00 85.99 ? 3005 HOH A O 1 HETATM 5331 O O . HOH N 9 . ? -43.930 -7.109 59.880 1.00 64.68 ? 3006 HOH A O 1 HETATM 5332 O O . HOH N 9 . ? -30.044 0.129 57.320 1.00 57.88 ? 3007 HOH A O 1 HETATM 5333 O O . HOH N 9 . ? -33.172 -13.616 31.163 1.00 66.58 ? 3008 HOH A O 1 HETATM 5334 O O . HOH N 9 . ? -40.934 -13.948 31.604 1.00 48.02 ? 3009 HOH A O 1 HETATM 5335 O O . HOH N 9 . ? -50.406 -18.107 1.016 1.00 68.19 ? 3010 HOH A O 1 HETATM 5336 O O . HOH N 9 . ? -45.204 -14.863 -0.357 1.00 67.38 ? 3011 HOH A O 1 HETATM 5337 O O . HOH N 9 . ? -32.542 -8.879 32.594 1.00 74.74 ? 3012 HOH A O 1 HETATM 5338 O O . HOH N 9 . ? -28.656 -1.815 56.109 1.00 66.10 ? 3013 HOH A O 1 HETATM 5339 O O . HOH N 9 . ? -41.499 -2.856 15.239 1.00 84.13 ? 3014 HOH A O 1 HETATM 5340 O O . HOH N 9 . ? -40.998 -14.477 90.708 1.00 110.82 ? 3015 HOH A O 1 HETATM 5341 O O . HOH N 9 . ? -53.903 -18.505 89.240 1.00 80.80 ? 3016 HOH A O 1 HETATM 5342 O O . HOH N 9 . ? -61.709 -32.872 -3.319 1.00 52.11 ? 3017 HOH A O 1 HETATM 5343 O O . HOH N 9 . ? -63.435 -34.644 -6.576 1.00 67.26 ? 3018 HOH A O 1 HETATM 5344 O O . HOH N 9 . ? -46.879 -30.861 -11.289 1.00 70.98 ? 3019 HOH A O 1 HETATM 5345 O O . HOH N 9 . ? -55.360 -22.931 -7.937 1.00 98.23 ? 3020 HOH A O 1 HETATM 5346 O O . HOH N 9 . ? -31.152 -13.249 8.574 1.00 67.71 ? 3021 HOH A O 1 HETATM 5347 O O . HOH N 9 . ? -32.936 -16.181 4.201 1.00 62.97 ? 3022 HOH A O 1 HETATM 5348 O O . HOH N 9 . ? -30.545 -17.038 4.604 1.00 66.39 ? 3023 HOH A O 1 HETATM 5349 O O . HOH N 9 . ? -38.273 -14.359 31.903 1.00 75.44 ? 3024 HOH A O 1 HETATM 5350 O O . HOH N 9 . ? -31.728 9.099 33.081 1.00 75.79 ? 3025 HOH A O 1 HETATM 5351 O O . HOH N 9 . ? -34.170 8.066 33.795 1.00 75.09 ? 3026 HOH A O 1 HETATM 5352 O O . HOH N 9 . ? -48.388 6.254 76.541 1.00 72.36 ? 3027 HOH A O 1 HETATM 5353 O O . HOH N 9 . ? -58.829 2.783 85.394 1.00 57.53 ? 3028 HOH A O 1 HETATM 5354 O O . HOH N 9 . ? -58.478 5.704 86.357 1.00 61.26 ? 3029 HOH A O 1 HETATM 5355 O O . HOH N 9 . ? -41.172 -23.059 24.176 1.00 67.95 ? 3030 HOH A O 1 HETATM 5356 O O . HOH N 9 . ? -32.605 -8.984 39.036 1.00 76.10 ? 3031 HOH A O 1 HETATM 5357 O O . HOH N 9 . ? -35.162 -9.507 36.795 1.00 80.13 ? 3032 HOH A O 1 HETATM 5358 O O . HOH N 9 . ? -50.133 -0.427 59.914 1.00 79.94 ? 3033 HOH A O 1 HETATM 5359 O O . HOH N 9 . ? -34.914 -11.953 75.277 1.00 71.17 ? 3034 HOH A O 1 HETATM 5360 O O . HOH N 9 . ? -37.938 -5.452 66.929 1.00 72.10 ? 3035 HOH A O 1 HETATM 5361 O O . HOH N 9 . ? -42.104 0.514 65.008 1.00 75.22 ? 3036 HOH A O 1 HETATM 5362 O O . HOH N 9 . ? -56.555 5.158 84.570 1.00 67.45 ? 3037 HOH A O 1 HETATM 5363 O O . HOH N 9 . ? -48.020 0.574 91.583 1.00 75.37 ? 3038 HOH A O 1 HETATM 5364 O O . HOH N 9 . ? -45.967 -0.559 92.939 1.00 57.59 ? 3039 HOH A O 1 HETATM 5365 O O . HOH N 9 . ? -47.375 -3.607 70.859 1.00 61.79 ? 3040 HOH A O 1 HETATM 5366 O O . HOH N 9 . ? -50.991 -4.869 79.263 1.00 74.02 ? 3041 HOH A O 1 HETATM 5367 O O . HOH N 9 . ? -40.743 -9.980 55.349 1.00 74.01 ? 3042 HOH A O 1 HETATM 5368 O O . HOH N 9 . ? -32.721 -10.771 49.291 1.00 76.33 ? 3043 HOH A O 1 HETATM 5369 O O . HOH N 9 . ? -34.783 6.787 36.864 1.00 72.10 ? 3044 HOH A O 1 HETATM 5370 O O . HOH N 9 . ? -35.787 -13.499 31.412 1.00 58.75 ? 3045 HOH A O 1 HETATM 5371 O O . HOH N 9 . ? -47.332 -5.116 48.552 1.00 66.88 ? 3046 HOH A O 1 HETATM 5372 O O . HOH N 9 . ? -50.813 -7.844 17.630 1.00 75.86 ? 3047 HOH A O 1 HETATM 5373 O O . HOH N 9 . ? -47.792 -1.463 94.712 1.00 73.52 ? 3048 HOH A O 1 HETATM 5374 O O . HOH N 9 . ? -43.629 -10.732 38.302 1.00 66.85 ? 3049 HOH A O 1 HETATM 5375 O O . HOH N 9 . ? -35.360 1.912 80.841 1.00 65.45 ? 3050 HOH A O 1 HETATM 5376 O O . HOH N 9 . ? -36.329 2.356 75.696 1.00 61.90 ? 3051 HOH A O 1 HETATM 5377 O O . HOH N 9 . ? -33.586 -15.005 6.540 1.00 76.45 ? 3052 HOH A O 1 HETATM 5378 O O . HOH N 9 . ? -35.381 -5.926 29.597 1.00 72.02 ? 3053 HOH A O 1 HETATM 5379 O O . HOH N 9 . ? -45.505 -13.101 80.748 1.00 70.01 ? 3054 HOH A O 1 HETATM 5380 O O . HOH N 9 . ? -47.460 1.375 94.093 1.00 75.94 ? 3055 HOH A O 1 HETATM 5381 O O . HOH N 9 . ? -31.091 0.352 29.679 1.00 102.78 ? 3056 HOH A O 1 HETATM 5382 O O . HOH N 9 . ? -32.202 6.585 32.218 1.00 59.12 ? 3057 HOH A O 1 HETATM 5383 O O . HOH N 9 . ? -43.555 -24.922 20.557 1.00 75.46 ? 3058 HOH A O 1 HETATM 5384 O O . HOH N 9 . ? -56.463 -19.324 88.239 1.00 70.69 ? 3059 HOH A O 1 HETATM 5385 O O . HOH N 9 . ? -41.580 -12.079 25.518 1.00 81.61 ? 3060 HOH A O 1 HETATM 5386 O O . HOH N 9 . ? -49.876 -17.610 3.921 1.00 67.32 ? 3061 HOH A O 1 HETATM 5387 O O . HOH N 9 . ? -37.598 -11.963 78.065 1.00 74.28 ? 3062 HOH A O 1 HETATM 5388 O O . HOH N 9 . ? -38.833 2.557 76.288 1.00 58.52 ? 3063 HOH A O 1 HETATM 5389 O O . HOH N 9 . ? -48.276 -30.987 17.452 1.00 94.10 ? 3064 HOH A O 1 HETATM 5390 O O . HOH N 9 . ? -44.841 3.666 80.039 1.00 69.77 ? 3065 HOH A O 1 HETATM 5391 O O . HOH N 9 . ? -35.721 -27.870 4.022 1.00 70.02 ? 3066 HOH A O 1 HETATM 5392 O O . HOH N 9 . ? -30.310 6.722 55.678 1.00 93.50 ? 3067 HOH A O 1 HETATM 5393 O O . HOH N 9 . ? -36.408 2.962 78.545 1.00 83.89 ? 3068 HOH A O 1 HETATM 5394 O O . HOH N 9 . ? -38.194 -29.883 5.165 1.00 61.89 ? 3069 HOH A O 1 HETATM 5395 O O . HOH N 9 . ? -38.324 -11.517 56.651 1.00 78.03 ? 3070 HOH A O 1 HETATM 5396 O O . HOH N 9 . ? -36.006 -25.444 2.786 1.00 81.46 ? 3071 HOH A O 1 HETATM 5397 O O . HOH N 9 . ? -28.336 -5.090 54.885 1.00 83.85 ? 3072 HOH A O 1 HETATM 5398 O O . HOH N 9 . ? -46.407 4.007 56.756 1.00 87.07 ? 3073 HOH A O 1 HETATM 5399 O O . HOH N 9 . ? -31.130 -26.855 10.153 1.00 76.29 ? 3074 HOH A O 1 HETATM 5400 O O . HOH N 9 . ? -41.976 -15.732 21.790 1.00 75.89 ? 3075 HOH A O 1 HETATM 5401 O O . HOH N 9 . ? -43.980 -12.919 1.574 1.00 83.58 ? 3076 HOH A O 1 HETATM 5402 O O . HOH N 9 . ? -38.153 -22.999 1.835 1.00 66.13 ? 3077 HOH A O 1 HETATM 5403 O O . HOH N 9 . ? -32.445 -28.342 11.873 1.00 76.33 ? 3078 HOH A O 1 HETATM 5404 O O . HOH N 9 . ? -38.945 -12.854 64.156 1.00 64.24 ? 3079 HOH A O 1 HETATM 5405 O O . HOH N 9 . ? -43.475 1.315 71.966 1.00 69.91 ? 3080 HOH A O 1 HETATM 5406 O O . HOH N 9 . ? -45.870 -13.395 89.748 1.00 83.73 ? 3081 HOH A O 1 HETATM 5407 O O . HOH N 9 . ? -30.855 -14.272 5.257 1.00 69.34 ? 3082 HOH A O 1 HETATM 5408 O O . HOH N 9 . ? -53.790 -20.168 0.991 1.00 65.95 ? 3083 HOH A O 1 HETATM 5409 O O . HOH N 9 . ? -37.361 -10.846 46.873 1.00 62.59 ? 3084 HOH A O 1 HETATM 5410 O O . HOH N 9 . ? -60.333 -38.240 0.879 1.00 69.98 ? 3085 HOH A O 1 HETATM 5411 O O . HOH N 9 . ? -67.192 -40.927 -0.306 1.00 48.45 ? 3086 HOH A O 1 HETATM 5412 O O . HOH N 9 . ? -53.121 -22.622 -0.005 1.00 70.62 ? 3087 HOH A O 1 HETATM 5413 O O . HOH N 9 . ? -29.177 -1.847 58.614 1.00 65.56 ? 3088 HOH A O 1 HETATM 5414 O O . HOH N 9 . ? -33.726 10.856 35.398 1.00 67.21 ? 3089 HOH A O 1 HETATM 5415 O O . HOH N 9 . ? -49.403 3.240 83.474 1.00 72.95 ? 3090 HOH A O 1 HETATM 5416 O O . HOH N 9 . ? -53.990 5.084 85.425 1.00 69.98 ? 3091 HOH A O 1 HETATM 5417 O O . HOH N 9 . ? -29.324 5.707 32.338 1.00 77.07 ? 3092 HOH A O 1 HETATM 5418 O O . HOH N 9 . ? -55.256 -24.970 -4.502 1.00 83.06 ? 3093 HOH A O 1 HETATM 5419 O O . HOH N 9 . ? -57.058 -25.077 -6.441 1.00 75.59 ? 3094 HOH A O 1 HETATM 5420 O O . HOH N 9 . ? -44.645 -15.458 19.695 1.00 74.93 ? 3095 HOH A O 1 HETATM 5421 O O . HOH N 9 . ? -44.158 -13.233 22.427 1.00 74.38 ? 3096 HOH A O 1 HETATM 5422 O O . HOH N 9 . ? -48.643 -9.519 27.013 1.00 84.59 ? 3097 HOH A O 1 HETATM 5423 O O . HOH N 9 . ? -44.097 -12.944 26.051 1.00 66.84 ? 3098 HOH A O 1 HETATM 5424 O O . HOH N 9 . ? -30.870 -22.286 23.553 1.00 69.75 ? 3099 HOH A O 1 HETATM 5425 O O . HOH N 9 . ? -44.607 -39.800 -0.302 1.00 109.54 ? 3100 HOH A O 1 HETATM 5426 O O . HOH N 9 . ? -40.486 -33.281 -7.240 1.00 80.06 ? 3101 HOH A O 1 HETATM 5427 O O . HOH N 9 . ? -36.026 -30.296 2.933 1.00 58.44 ? 3102 HOH A O 1 HETATM 5428 O O . HOH N 9 . ? -59.523 -31.078 -2.296 1.00 69.07 ? 3103 HOH A O 1 HETATM 5429 O O . HOH N 9 . ? -33.793 -7.873 20.095 1.00 67.13 ? 3104 HOH A O 1 HETATM 5430 O O . HOH N 9 . ? -43.261 -33.112 -14.515 1.00 66.63 ? 3105 HOH A O 1 HETATM 5431 O O . HOH N 9 . ? -31.462 4.861 29.909 1.00 87.87 ? 3106 HOH A O 1 HETATM 5432 O O . HOH N 9 . ? -46.280 -0.207 62.455 1.00 78.20 ? 3107 HOH A O 1 HETATM 5433 O O . HOH N 9 . ? -42.332 -12.639 52.170 1.00 80.91 ? 3108 HOH A O 1 HETATM 5434 O O . HOH N 9 . ? -39.306 -10.793 51.416 1.00 81.91 ? 3109 HOH A O 1 HETATM 5435 O O . HOH N 9 . ? -37.237 -5.431 15.197 1.00 82.37 ? 3110 HOH A O 1 HETATM 5436 O O . HOH N 9 . ? -39.296 -5.976 13.210 1.00 84.11 ? 3111 HOH A O 1 HETATM 5437 O O . HOH N 9 . ? -49.545 -2.847 16.306 1.00 85.70 ? 3112 HOH A O 1 HETATM 5438 O O . HOH N 9 . ? -34.416 -0.767 63.850 1.00 67.85 ? 3113 HOH A O 1 HETATM 5439 O O . HOH N 9 . ? -41.881 8.859 66.695 1.00 61.60 ? 3114 HOH A O 1 HETATM 5440 O O . HOH N 9 . ? -44.274 6.347 65.055 1.00 93.51 ? 3115 HOH A O 1 HETATM 5441 O O . HOH N 9 . ? -41.147 7.274 68.656 1.00 78.43 ? 3116 HOH A O 1 HETATM 5442 O O . HOH N 9 . ? -52.769 -13.187 98.299 1.00 84.76 ? 3117 HOH A O 1 HETATM 5443 O O . HOH N 9 . ? -38.445 5.182 76.447 1.00 83.20 ? 3118 HOH A O 1 HETATM 5444 O O . HOH N 9 . ? -48.670 7.431 79.212 1.00 56.79 ? 3119 HOH A O 1 HETATM 5445 O O . HOH N 9 . ? -52.774 3.693 80.636 1.00 72.78 ? 3120 HOH A O 1 HETATM 5446 O O . HOH N 9 . ? -62.666 -1.058 95.364 1.00 71.49 ? 3121 HOH A O 1 HETATM 5447 O O . HOH N 9 . ? -60.293 -1.097 96.619 1.00 70.40 ? 3122 HOH A O 1 HETATM 5448 O O . HOH N 9 . ? -47.600 -13.120 17.322 1.00 52.46 ? 3123 HOH A O 1 HETATM 5449 O O . HOH N 9 . ? -49.437 -15.495 17.068 1.00 70.36 ? 3124 HOH A O 1 HETATM 5450 O O . HOH N 9 . ? -49.189 -13.425 15.324 1.00 60.88 ? 3125 HOH A O 1 HETATM 5451 O O . HOH N 9 . ? -33.682 -11.850 80.023 1.00 88.71 ? 3126 HOH A O 1 HETATM 5452 O O . HOH N 9 . ? -32.714 -11.185 77.272 1.00 97.24 ? 3127 HOH A O 1 HETATM 5453 O O . HOH O 9 . ? -70.086 4.860 38.516 1.00 74.82 ? 3001 HOH L O 1 HETATM 5454 O O . HOH O 9 . ? -57.870 0.835 58.035 1.00 61.06 ? 3002 HOH L O 1 HETATM 5455 O O . HOH O 9 . ? -74.410 17.128 37.329 1.00 59.77 ? 3003 HOH L O 1 HETATM 5456 O O . HOH O 9 . ? -82.423 17.698 36.128 1.00 75.88 ? 3004 HOH L O 1 HETATM 5457 O O . HOH O 9 . ? -106.105 9.184 42.577 1.00 100.58 ? 3005 HOH L O 1 HETATM 5458 O O . HOH O 9 . ? -49.229 8.295 52.213 1.00 57.40 ? 3006 HOH L O 1 HETATM 5459 O O . HOH O 9 . ? -66.310 26.312 55.501 1.00 69.70 ? 3007 HOH L O 1 HETATM 5460 O O . HOH O 9 . ? -64.334 -0.813 52.053 1.00 55.91 ? 3008 HOH L O 1 HETATM 5461 O O . HOH O 9 . ? -75.609 8.361 63.162 1.00 58.08 ? 3009 HOH L O 1 HETATM 5462 O O . HOH O 9 . ? -81.113 18.246 50.667 1.00 57.28 ? 3010 HOH L O 1 HETATM 5463 O O . HOH O 9 . ? -74.539 14.371 37.447 1.00 72.87 ? 3011 HOH L O 1 HETATM 5464 O O . HOH O 9 . ? -77.775 7.143 42.827 1.00 80.47 ? 3012 HOH L O 1 HETATM 5465 O O . HOH O 9 . ? -84.880 14.423 50.689 1.00 63.80 ? 3013 HOH L O 1 HETATM 5466 O O . HOH O 9 . ? -67.732 6.954 48.805 1.00 70.76 ? 3014 HOH L O 1 HETATM 5467 O O . HOH O 9 . ? -63.814 0.895 78.459 1.00 51.26 ? 3015 HOH L O 1 HETATM 5468 O O . HOH O 9 . ? -55.268 8.603 80.410 1.00 68.77 ? 3016 HOH L O 1 HETATM 5469 O O . HOH O 9 . ? -81.427 5.689 51.146 1.00 70.21 ? 3017 HOH L O 1 HETATM 5470 O O . HOH O 9 . ? -87.116 2.044 51.851 1.00 78.12 ? 3018 HOH L O 1 HETATM 5471 O O . HOH O 9 . ? -81.592 2.123 51.613 1.00 62.18 ? 3019 HOH L O 1 HETATM 5472 O O . HOH O 9 . ? -78.547 0.935 51.692 1.00 82.22 ? 3020 HOH L O 1 HETATM 5473 O O . HOH O 9 . ? -50.769 11.648 52.346 1.00 77.23 ? 3021 HOH L O 1 HETATM 5474 O O . HOH O 9 . ? -55.655 12.785 43.993 1.00 80.02 ? 3022 HOH L O 1 HETATM 5475 O O . HOH O 9 . ? -61.350 -0.927 55.825 1.00 74.48 ? 3023 HOH L O 1 HETATM 5476 O O . HOH O 9 . ? -75.664 18.274 61.150 1.00 96.23 ? 3024 HOH L O 1 HETATM 5477 O O . HOH O 9 . ? -77.888 15.688 63.619 1.00 79.67 ? 3025 HOH L O 1 HETATM 5478 O O . HOH O 9 . ? -62.930 9.822 51.695 1.00 79.00 ? 3026 HOH L O 1 HETATM 5479 O O . HOH O 9 . ? -89.337 -2.195 44.694 1.00 66.10 ? 3027 HOH L O 1 HETATM 5480 O O . HOH O 9 . ? -102.482 -4.272 45.824 1.00 91.69 ? 3028 HOH L O 1 HETATM 5481 O O . HOH O 9 . ? -99.433 -12.511 44.566 1.00 69.13 ? 3029 HOH L O 1 HETATM 5482 O O . HOH O 9 . ? -88.243 16.093 46.300 1.00 68.83 ? 3030 HOH L O 1 HETATM 5483 O O . HOH O 9 . ? -55.909 -0.437 74.736 1.00 72.01 ? 3031 HOH L O 1 HETATM 5484 O O . HOH O 9 . ? -73.475 6.669 61.926 1.00 55.39 ? 3032 HOH L O 1 HETATM 5485 O O . HOH O 9 . ? -104.603 -2.491 54.891 1.00 86.33 ? 3033 HOH L O 1 HETATM 5486 O O . HOH O 9 . ? -99.929 5.718 46.354 1.00 60.53 ? 3034 HOH L O 1 HETATM 5487 O O . HOH O 9 . ? -106.283 -2.798 41.730 1.00 75.82 ? 3035 HOH L O 1 HETATM 5488 O O . HOH O 9 . ? -50.534 15.237 49.544 1.00 68.84 ? 3036 HOH L O 1 HETATM 5489 O O . HOH O 9 . ? -54.511 18.956 69.316 1.00 64.55 ? 3037 HOH L O 1 HETATM 5490 O O . HOH O 9 . ? -55.681 11.663 81.038 1.00 62.27 ? 3038 HOH L O 1 HETATM 5491 O O . HOH O 9 . ? -74.453 23.911 52.160 1.00 88.46 ? 3039 HOH L O 1 HETATM 5492 O O . HOH O 9 . ? -96.988 10.776 42.803 1.00 76.00 ? 3040 HOH L O 1 HETATM 5493 O O . HOH O 9 . ? -64.160 -3.611 52.635 1.00 55.49 ? 3041 HOH L O 1 HETATM 5494 O O . HOH O 9 . ? -65.418 1.575 54.279 1.00 37.33 ? 3042 HOH L O 1 HETATM 5495 O O . HOH O 9 . ? -65.951 5.116 47.680 1.00 71.05 ? 3043 HOH L O 1 HETATM 5496 O O . HOH O 9 . ? -73.130 4.659 48.484 1.00 79.64 ? 3044 HOH L O 1 HETATM 5497 O O . HOH O 9 . ? -66.503 14.618 80.027 1.00 73.91 ? 3045 HOH L O 1 HETATM 5498 O O . HOH O 9 . ? -63.599 3.954 54.299 1.00 70.82 ? 3046 HOH L O 1 HETATM 5499 O O . HOH O 9 . ? -93.148 16.498 40.029 1.00 82.38 ? 3047 HOH L O 1 HETATM 5500 O O . HOH O 9 . ? -55.288 13.992 79.874 1.00 58.22 ? 3048 HOH L O 1 HETATM 5501 O O . HOH O 9 . ? -68.699 12.364 65.736 1.00 60.87 ? 3049 HOH L O 1 HETATM 5502 O O . HOH O 9 . ? -94.461 -5.310 46.330 1.00 87.47 ? 3050 HOH L O 1 HETATM 5503 O O . HOH O 9 . ? -84.493 2.246 51.121 1.00 78.17 ? 3051 HOH L O 1 HETATM 5504 O O . HOH O 9 . ? -66.040 -4.297 50.871 1.00 81.79 ? 3052 HOH L O 1 HETATM 5505 O O . HOH O 9 . ? -100.284 -12.065 29.955 1.00 85.34 ? 3053 HOH L O 1 HETATM 5506 O O . HOH O 9 . ? -86.092 17.277 50.537 1.00 67.97 ? 3054 HOH L O 1 HETATM 5507 O O . HOH O 9 . ? -71.799 11.621 47.198 1.00 71.15 ? 3055 HOH L O 1 HETATM 5508 O O . HOH O 9 . ? -107.132 -8.995 26.643 1.00 69.90 ? 3056 HOH L O 1 HETATM 5509 O O . HOH O 9 . ? -108.833 -8.340 28.632 1.00 70.49 ? 3057 HOH L O 1 HETATM 5510 O O . HOH O 9 . ? -108.319 -6.251 26.959 1.00 81.53 ? 3058 HOH L O 1 HETATM 5511 O O . HOH O 9 . ? -54.061 18.726 66.340 1.00 70.15 ? 3059 HOH L O 1 HETATM 5512 O O . HOH O 9 . ? -56.379 20.561 70.566 1.00 77.60 ? 3060 HOH L O 1 HETATM 5513 O O . HOH O 9 . ? -90.919 22.042 35.786 1.00 56.83 ? 3061 HOH L O 1 HETATM 5514 O O . HOH O 9 . ? -93.715 3.888 29.477 1.00 68.57 ? 3062 HOH L O 1 HETATM 5515 O O . HOH O 9 . ? -92.015 6.403 27.552 1.00 76.16 ? 3063 HOH L O 1 HETATM 5516 O O . HOH O 9 . ? -93.870 8.219 28.317 1.00 77.15 ? 3064 HOH L O 1 HETATM 5517 O O . HOH O 9 . ? -93.767 -2.516 25.478 1.00 64.68 ? 3065 HOH L O 1 HETATM 5518 O O . HOH O 9 . ? -52.547 9.636 79.125 1.00 77.35 ? 3066 HOH L O 1 HETATM 5519 O O . HOH O 9 . ? -55.931 22.659 57.476 1.00 72.60 ? 3067 HOH L O 1 HETATM 5520 O O . HOH O 9 . ? -63.595 1.821 48.977 1.00 54.39 ? 3068 HOH L O 1 HETATM 5521 O O . HOH O 9 . ? -61.050 1.625 47.999 1.00 71.59 ? 3069 HOH L O 1 HETATM 5522 O O . HOH O 9 . ? -60.268 4.509 49.049 1.00 69.89 ? 3070 HOH L O 1 HETATM 5523 O O . HOH O 9 . ? -46.927 7.007 52.459 1.00 55.59 ? 3071 HOH L O 1 HETATM 5524 O O . HOH O 9 . ? -47.636 8.926 54.186 1.00 78.45 ? 3072 HOH L O 1 HETATM 5525 O O . HOH O 9 . ? -97.013 -21.803 40.625 1.00 66.75 ? 3073 HOH L O 1 HETATM 5526 O O . HOH O 9 . ? -83.442 19.611 50.201 1.00 76.18 ? 3074 HOH L O 1 HETATM 5527 O O . HOH O 9 . ? -97.814 7.445 46.904 1.00 91.08 ? 3075 HOH L O 1 HETATM 5528 O O . HOH O 9 . ? -96.452 6.309 49.119 1.00 67.83 ? 3076 HOH L O 1 HETATM 5529 O O . HOH O 9 . ? -105.605 9.192 45.245 1.00 77.63 ? 3077 HOH L O 1 HETATM 5530 O O . HOH O 9 . ? -103.742 9.538 47.520 1.00 93.96 ? 3078 HOH L O 1 HETATM 5531 O O . HOH O 9 . ? -93.556 21.309 36.041 1.00 71.46 ? 3079 HOH L O 1 HETATM 5532 O O . HOH O 9 . ? -94.524 -0.327 23.718 1.00 77.18 ? 3080 HOH L O 1 HETATM 5533 O O . HOH O 9 . ? -109.753 -3.351 40.653 0.50 124.94 ? 3081 HOH L O 1 HETATM 5534 O O . HOH O 9 . ? -109.311 -6.560 39.005 1.00 65.29 ? 3082 HOH L O 1 HETATM 5535 O O . HOH O 9 . ? -95.819 -22.301 43.036 1.00 102.95 ? 3083 HOH L O 1 HETATM 5536 O O . HOH O 9 . ? -94.435 -21.857 39.875 1.00 86.03 ? 3084 HOH L O 1 HETATM 5537 O O . HOH O 9 . ? -73.648 19.882 76.150 1.00 72.41 ? 3085 HOH L O 1 HETATM 5538 O O . HOH O 9 . ? -67.235 -2.155 72.532 1.00 55.67 ? 3086 HOH L O 1 HETATM 5539 O O . HOH P 9 . ? -86.867 -17.598 64.203 1.00 83.23 ? 3001 HOH H O 1 HETATM 5540 O O . HOH P 9 . ? -60.493 -9.379 53.193 1.00 59.72 ? 3002 HOH H O 1 HETATM 5541 O O . HOH P 9 . ? -63.150 -27.222 63.850 1.00 74.51 ? 3003 HOH H O 1 HETATM 5542 O O . HOH P 9 . ? -53.650 -5.743 66.949 1.00 53.20 ? 3004 HOH H O 1 HETATM 5543 O O . HOH P 9 . ? -85.864 -3.843 47.682 1.00 49.89 ? 3005 HOH H O 1 HETATM 5544 O O . HOH P 9 . ? -90.699 -10.327 50.125 1.00 86.99 ? 3006 HOH H O 1 HETATM 5545 O O . HOH P 9 . ? -93.363 -14.854 42.253 1.00 75.38 ? 3007 HOH H O 1 HETATM 5546 O O . HOH P 9 . ? -72.857 -7.092 73.888 1.00 83.24 ? 3008 HOH H O 1 HETATM 5547 O O . HOH P 9 . ? -43.085 -12.240 58.420 1.00 76.59 ? 3009 HOH H O 1 HETATM 5548 O O . HOH P 9 . ? -60.533 -23.822 58.989 1.00 70.48 ? 3010 HOH H O 1 HETATM 5549 O O . HOH P 9 . ? -74.370 4.522 63.227 1.00 71.60 ? 3011 HOH H O 1 HETATM 5550 O O . HOH P 9 . ? -73.217 -4.023 68.596 1.00 77.97 ? 3012 HOH H O 1 HETATM 5551 O O . HOH P 9 . ? -71.789 -10.996 51.668 1.00 68.68 ? 3013 HOH H O 1 HETATM 5552 O O . HOH P 9 . ? -86.260 -3.581 45.084 1.00 58.40 ? 3014 HOH H O 1 HETATM 5553 O O . HOH P 9 . ? -62.392 -22.560 57.597 1.00 64.05 ? 3015 HOH H O 1 HETATM 5554 O O . HOH P 9 . ? -97.507 -18.788 44.959 1.00 60.89 ? 3016 HOH H O 1 HETATM 5555 O O . HOH P 9 . ? -95.614 -19.449 46.922 1.00 77.51 ? 3017 HOH H O 1 HETATM 5556 O O . HOH P 9 . ? -66.175 -19.386 52.576 1.00 60.39 ? 3018 HOH H O 1 HETATM 5557 O O . HOH P 9 . ? -52.388 -8.116 73.500 1.00 41.51 ? 3019 HOH H O 1 HETATM 5558 O O . HOH P 9 . ? -62.936 -21.311 68.749 1.00 55.28 ? 3020 HOH H O 1 HETATM 5559 O O . HOH P 9 . ? -59.690 -23.702 67.438 1.00 93.83 ? 3021 HOH H O 1 HETATM 5560 O O . HOH P 9 . ? -59.789 -25.340 69.763 1.00 70.00 ? 3022 HOH H O 1 HETATM 5561 O O . HOH P 9 . ? -68.515 -19.880 72.388 1.00 55.76 ? 3023 HOH H O 1 HETATM 5562 O O . HOH P 9 . ? -46.447 -15.766 63.197 1.00 70.13 ? 3024 HOH H O 1 HETATM 5563 O O . HOH P 9 . ? -78.171 -24.584 63.022 1.00 84.45 ? 3025 HOH H O 1 HETATM 5564 O O . HOH P 9 . ? -84.043 4.483 34.336 1.00 84.16 ? 3026 HOH H O 1 HETATM 5565 O O . HOH P 9 . ? -70.846 -12.112 54.687 1.00 59.55 ? 3027 HOH H O 1 HETATM 5566 O O . HOH P 9 . ? -66.285 -5.672 53.232 1.00 80.87 ? 3028 HOH H O 1 HETATM 5567 O O . HOH P 9 . ? -45.371 -22.348 67.513 1.00 85.92 ? 3029 HOH H O 1 HETATM 5568 O O . HOH P 9 . ? -72.560 -6.227 36.780 1.00 85.15 ? 3030 HOH H O 1 HETATM 5569 O O . HOH P 9 . ? -76.980 -16.741 50.150 1.00 79.18 ? 3031 HOH H O 1 HETATM 5570 O O . HOH P 9 . ? -61.084 -24.656 63.339 1.00 87.32 ? 3032 HOH H O 1 HETATM 5571 O O . HOH P 9 . ? -78.548 -16.899 23.572 1.00 70.44 ? 3033 HOH H O 1 HETATM 5572 O O . HOH P 9 . ? -48.808 -7.038 46.463 1.00 73.05 ? 3034 HOH H O 1 HETATM 5573 O O . HOH P 9 . ? -55.859 -21.141 70.137 1.00 71.49 ? 3035 HOH H O 1 HETATM 5574 O O . HOH P 9 . ? -80.726 -12.823 55.926 1.00 77.37 ? 3036 HOH H O 1 HETATM 5575 O O . HOH P 9 . ? -95.388 -13.206 44.012 1.00 66.46 ? 3037 HOH H O 1 HETATM 5576 O O . HOH P 9 . ? -50.923 -24.451 66.275 1.00 69.13 ? 3038 HOH H O 1 HETATM 5577 O O . HOH P 9 . ? -82.107 -24.109 55.520 1.00 87.04 ? 3039 HOH H O 1 HETATM 5578 O O . HOH P 9 . ? -62.131 -24.851 56.160 1.00 81.74 ? 3040 HOH H O 1 HETATM 5579 O O . HOH P 9 . ? -74.857 -23.848 70.583 1.00 62.14 ? 3041 HOH H O 1 HETATM 5580 O O . HOH P 9 . ? -43.681 -14.888 59.525 1.00 61.32 ? 3042 HOH H O 1 HETATM 5581 O O . HOH P 9 . ? -62.085 -18.798 53.571 1.00 55.37 ? 3043 HOH H O 1 HETATM 5582 O O . HOH P 9 . ? -69.971 -5.852 78.943 1.00 51.54 ? 3044 HOH H O 1 HETATM 5583 O O . HOH P 9 . ? -61.808 -18.152 56.163 1.00 61.10 ? 3045 HOH H O 1 HETATM 5584 O O . HOH P 9 . ? -64.291 -20.103 54.300 1.00 70.18 ? 3046 HOH H O 1 HETATM 5585 O O . HOH P 9 . ? -50.728 -2.326 54.391 1.00 76.37 ? 3047 HOH H O 1 HETATM 5586 O O . HOH P 9 . ? -60.058 -16.041 66.954 1.00 74.12 ? 3048 HOH H O 1 HETATM 5587 O O . HOH P 9 . ? -74.512 -25.307 62.765 1.00 87.65 ? 3049 HOH H O 1 HETATM 5588 O O . HOH P 9 . ? -82.276 -16.998 29.699 1.00 67.49 ? 3050 HOH H O 1 HETATM 5589 O O . HOH P 9 . ? -79.626 -17.410 29.334 1.00 81.57 ? 3051 HOH H O 1 HETATM 5590 O O . HOH P 9 . ? -51.994 -10.421 74.903 1.00 65.78 ? 3052 HOH H O 1 HETATM 5591 O O . HOH P 9 . ? -71.634 4.924 36.570 1.00 64.13 ? 3053 HOH H O 1 HETATM 5592 O O . HOH P 9 . ? -57.998 -23.164 58.383 1.00 66.07 ? 3054 HOH H O 1 HETATM 5593 O O . HOH P 9 . ? -77.450 -7.202 67.004 1.00 85.02 ? 3055 HOH H O 1 HETATM 5594 O O . HOH P 9 . ? -77.922 -11.419 59.815 1.00 67.89 ? 3056 HOH H O 1 HETATM 5595 O O . HOH P 9 . ? -90.450 -1.219 24.503 1.00 80.82 ? 3057 HOH H O 1 HETATM 5596 O O . HOH P 9 . ? -67.364 0.572 36.644 1.00 76.97 ? 3058 HOH H O 1 HETATM 5597 O O . HOH P 9 . ? -79.609 1.683 35.938 1.00 88.37 ? 3059 HOH H O 1 HETATM 5598 O O . HOH P 9 . ? -44.093 -10.765 56.349 1.00 68.90 ? 3060 HOH H O 1 HETATM 5599 O O . HOH P 9 . ? -95.295 -16.587 44.564 1.00 77.37 ? 3061 HOH H O 1 HETATM 5600 O O . HOH P 9 . ? -77.132 -14.085 23.355 1.00 98.71 ? 3062 HOH H O 1 HETATM 5601 O O . HOH P 9 . ? -66.698 -21.063 54.505 1.00 60.48 ? 3063 HOH H O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 VAL 1 186 186 VAL VAL A . n A 1 2 LEU 2 187 187 LEU LEU A . n A 1 3 PRO 3 188 188 PRO PRO A . n A 1 4 ALA 4 189 189 ALA ALA A . n A 1 5 THR 5 190 190 THR THR A . n A 1 6 PRO 6 191 191 PRO PRO A . n A 1 7 PRO 7 192 192 PRO PRO A . n A 1 8 GLN 8 193 193 GLN GLN A . n A 1 9 LEU 9 194 194 LEU LEU A . n A 1 10 VAL 10 195 195 VAL VAL A . n A 1 11 SER 11 196 196 SER SER A . n A 1 12 PRO 12 197 197 PRO PRO A . n A 1 13 ARG 13 198 198 ARG ARG A . n A 1 14 VAL 14 199 199 VAL VAL A . n A 1 15 LEU 15 200 200 LEU LEU A . n A 1 16 GLU 16 201 201 GLU GLU A . n A 1 17 VAL 17 202 202 VAL VAL A . n A 1 18 ASP 18 203 203 ASP ASP A . n A 1 19 THR 19 204 204 THR THR A . n A 1 20 GLN 20 205 205 GLN GLN A . n A 1 21 GLY 21 206 206 GLY GLY A . n A 1 22 THR 22 207 207 THR THR A . n A 1 23 VAL 23 208 208 VAL VAL A . n A 1 24 VAL 24 209 209 VAL VAL A . n A 1 25 CYS 25 210 210 CYS CYS A . n A 1 26 SER 26 211 211 SER SER A . n A 1 27 LEU 27 212 212 LEU LEU A . n A 1 28 ASP 28 213 213 ASP ASP A . n A 1 29 GLY 29 214 214 GLY GLY A . n A 1 30 LEU 30 215 215 LEU LEU A . n A 1 31 PHE 31 216 216 PHE PHE A . n A 1 32 PRO 32 217 217 PRO PRO A . n A 1 33 VAL 33 218 218 VAL VAL A . n A 1 34 SER 34 219 219 SER SER A . n A 1 35 GLU 35 220 220 GLU GLU A . n A 1 36 ALA 36 221 221 ALA ALA A . n A 1 37 GLN 37 222 222 GLN GLN A . n A 1 38 VAL 38 223 223 VAL VAL A . n A 1 39 HIS 39 224 224 HIS HIS A . n A 1 40 LEU 40 225 225 LEU LEU A . n A 1 41 ALA 41 226 226 ALA ALA A . n A 1 42 LEU 42 227 227 LEU LEU A . n A 1 43 GLY 43 228 228 GLY GLY A . n A 1 44 ASP 44 229 229 ASP ASP A . n A 1 45 GLN 45 230 230 GLN GLN A . n A 1 46 ARG 46 231 231 ARG ARG A . n A 1 47 LEU 47 232 232 LEU LEU A . n A 1 48 ASN 48 233 233 ASN ASN A . n A 1 49 PRO 49 234 234 PRO PRO A . n A 1 50 THR 50 235 235 THR THR A . n A 1 51 VAL 51 236 236 VAL VAL A . n A 1 52 THR 52 237 237 THR THR A . n A 1 53 TYR 53 238 238 TYR TYR A . n A 1 54 GLY 54 239 239 GLY GLY A . n A 1 55 ASN 55 240 240 ASN ASN A . n A 1 56 ASP 56 241 241 ASP ASP A . n A 1 57 SER 57 242 242 SER SER A . n A 1 58 PHE 58 243 243 PHE PHE A . n A 1 59 SER 59 244 244 SER SER A . n A 1 60 ALA 60 245 245 ALA ALA A . n A 1 61 LYS 61 246 246 LYS LYS A . n A 1 62 ALA 62 247 247 ALA ALA A . n A 1 63 SER 63 248 248 SER SER A . n A 1 64 VAL 64 249 249 VAL VAL A . n A 1 65 SER 65 250 250 SER SER A . n A 1 66 VAL 66 251 251 VAL VAL A . n A 1 67 THR 67 252 252 THR THR A . n A 1 68 ALA 68 253 253 ALA ALA A . n A 1 69 GLU 69 254 254 GLU GLU A . n A 1 70 ASP 70 255 255 ASP ASP A . n A 1 71 GLU 71 256 256 GLU GLU A . n A 1 72 GLY 72 257 257 GLY GLY A . n A 1 73 THR 73 258 258 THR THR A . n A 1 74 GLN 74 259 259 GLN GLN A . n A 1 75 ARG 75 260 260 ARG ARG A . n A 1 76 LEU 76 261 261 LEU LEU A . n A 1 77 THR 77 262 262 THR THR A . n A 1 78 CYS 78 263 263 CYS CYS A . n A 1 79 ALA 79 264 264 ALA ALA A . n A 1 80 VAL 80 265 265 VAL VAL A . n A 1 81 ILE 81 266 266 ILE ILE A . n A 1 82 LEU 82 267 267 LEU LEU A . n A 1 83 GLY 83 268 268 GLY GLY A . n A 1 84 ASN 84 269 269 ASN ASN A . n A 1 85 GLN 85 270 270 GLN GLN A . n A 1 86 SER 86 271 271 SER SER A . n A 1 87 GLN 87 272 272 GLN GLN A . n A 1 88 GLU 88 273 273 GLU GLU A . n A 1 89 THR 89 274 274 THR THR A . n A 1 90 LEU 90 275 275 LEU LEU A . n A 1 91 GLN 91 276 276 GLN GLN A . n A 1 92 THR 92 277 277 THR THR A . n A 1 93 VAL 93 278 278 VAL VAL A . n A 1 94 THR 94 279 279 THR THR A . n A 1 95 ILE 95 280 280 ILE ILE A . n A 1 96 TYR 96 281 281 TYR TYR A . n A 1 97 SER 97 282 282 SER SER A . n A 1 98 PHE 98 283 283 PHE PHE A . n A 1 99 PRO 99 284 284 PRO PRO A . n A 1 100 ALA 100 285 285 ALA ALA A . n A 1 101 PRO 101 286 286 PRO PRO A . n A 1 102 ASN 102 287 287 ASN ASN A . n A 1 103 VAL 103 288 288 VAL VAL A . n A 1 104 ILE 104 289 289 ILE ILE A . n A 1 105 LEU 105 290 290 LEU LEU A . n A 1 106 THR 106 291 291 THR THR A . n A 1 107 LYS 107 292 292 LYS LYS A . n A 1 108 PRO 108 293 293 PRO PRO A . n A 1 109 GLU 109 294 294 GLU GLU A . n A 1 110 VAL 110 295 295 VAL VAL A . n A 1 111 SER 111 296 296 SER SER A . n A 1 112 GLU 112 297 297 GLU GLU A . n A 1 113 GLY 113 298 298 GLY GLY A . n A 1 114 THR 114 299 299 THR THR A . n A 1 115 GLU 115 300 300 GLU GLU A . n A 1 116 VAL 116 301 301 VAL VAL A . n A 1 117 THR 117 302 302 THR THR A . n A 1 118 VAL 118 303 303 VAL VAL A . n A 1 119 LYS 119 304 304 LYS LYS A . n A 1 120 CYS 120 305 305 CYS CYS A . n A 1 121 GLU 121 306 306 GLU GLU A . n A 1 122 ALA 122 307 307 ALA ALA A . n A 1 123 HIS 123 308 308 HIS HIS A . n A 1 124 PRO 124 309 309 PRO PRO A . n A 1 125 ARG 125 310 310 ARG ARG A . n A 1 126 ALA 126 311 311 ALA ALA A . n A 1 127 LYS 127 312 312 LYS LYS A . n A 1 128 VAL 128 313 313 VAL VAL A . n A 1 129 THR 129 314 314 THR THR A . n A 1 130 LEU 130 315 315 LEU LEU A . n A 1 131 ASN 131 316 316 ASN ASN A . n A 1 132 GLY 132 317 317 GLY GLY A . n A 1 133 VAL 133 318 318 VAL VAL A . n A 1 134 PRO 134 319 319 PRO PRO A . n A 1 135 ALA 135 320 320 ALA ALA A . n A 1 136 GLN 136 321 321 GLN GLN A . n A 1 137 PRO 137 322 322 PRO PRO A . n A 1 138 LEU 138 323 323 LEU LEU A . n A 1 139 GLY 139 324 324 GLY GLY A . n A 1 140 PRO 140 325 325 PRO PRO A . n A 1 141 ARG 141 326 326 ARG ARG A . n A 1 142 ALA 142 327 327 ALA ALA A . n A 1 143 GLN 143 328 328 GLN GLN A . n A 1 144 LEU 144 329 329 LEU LEU A . n A 1 145 LEU 145 330 330 LEU LEU A . n A 1 146 LEU 146 331 331 LEU LEU A . n A 1 147 LYS 147 332 332 LYS LYS A . n A 1 148 ALA 148 333 333 ALA ALA A . n A 1 149 THR 149 334 334 THR THR A . n A 1 150 PRO 150 335 335 PRO PRO A . n A 1 151 GLU 151 336 336 GLU GLU A . n A 1 152 ASP 152 337 337 ASP ASP A . n A 1 153 ASN 153 338 338 ASN ASN A . n A 1 154 GLY 154 339 339 GLY GLY A . n A 1 155 ARG 155 340 340 ARG ARG A . n A 1 156 SER 156 341 341 SER SER A . n A 1 157 PHE 157 342 342 PHE PHE A . n A 1 158 SER 158 343 343 SER SER A . n A 1 159 CYS 159 344 344 CYS CYS A . n A 1 160 SER 160 345 345 SER SER A . n A 1 161 ALA 161 346 346 ALA ALA A . n A 1 162 THR 162 347 347 THR THR A . n A 1 163 LEU 163 348 348 LEU LEU A . n A 1 164 GLU 164 349 349 GLU GLU A . n A 1 165 VAL 165 350 350 VAL VAL A . n A 1 166 ALA 166 351 351 ALA ALA A . n A 1 167 GLY 167 352 352 GLY GLY A . n A 1 168 GLN 168 353 353 GLN GLN A . n A 1 169 LEU 169 354 354 LEU LEU A . n A 1 170 ILE 170 355 355 ILE ILE A . n A 1 171 HIS 171 356 356 HIS HIS A . n A 1 172 LYS 172 357 357 LYS LYS A . n A 1 173 ASN 173 358 358 ASN ASN A . n A 1 174 GLN 174 359 359 GLN GLN A . n A 1 175 THR 175 360 360 THR THR A . n A 1 176 ARG 176 361 361 ARG ARG A . n A 1 177 GLU 177 362 362 GLU GLU A . n A 1 178 LEU 178 363 363 LEU LEU A . n A 1 179 ARG 179 364 364 ARG ARG A . n A 1 180 VAL 180 365 365 VAL VAL A . n A 1 181 LEU 181 366 366 LEU LEU A . n A 1 182 TYR 182 367 367 TYR TYR A . n A 1 183 GLY 183 368 368 GLY GLY A . n A 1 184 PRO 184 369 369 PRO PRO A . n A 1 185 ARG 185 370 370 ARG ARG A . n A 1 186 LEU 186 371 371 LEU LEU A . n A 1 187 ASP 187 372 372 ASP ASP A . n A 1 188 GLU 188 373 373 GLU GLU A . n A 1 189 ARG 189 374 374 ARG ARG A . n A 1 190 ASP 190 375 375 ASP ASP A . n A 1 191 CYS 191 376 376 CYS CYS A . n A 1 192 PRO 192 377 377 PRO PRO A . n A 1 193 GLY 193 378 378 GLY GLY A . n A 1 194 ASN 194 379 379 ASN ASN A . n A 1 195 TRP 195 380 380 TRP TRP A . n A 1 196 THR 196 381 381 THR THR A . n A 1 197 TRP 197 382 382 TRP TRP A . n A 1 198 PRO 198 383 383 PRO PRO A . n A 1 199 GLU 199 384 384 GLU GLU A . n A 1 200 ASN 200 385 385 ASN ASN A . n A 1 201 SER 201 386 386 SER SER A . n A 1 202 GLN 202 387 387 GLN GLN A . n A 1 203 GLN 203 388 388 GLN GLN A . n A 1 204 THR 204 389 389 THR THR A . n A 1 205 PRO 205 390 390 PRO PRO A . n A 1 206 MET 206 391 391 MET MET A . n A 1 207 CYS 207 392 392 CYS CYS A . n A 1 208 GLN 208 393 393 GLN GLN A . n A 1 209 ALA 209 394 394 ALA ALA A . n A 1 210 TRP 210 395 395 TRP TRP A . n A 1 211 GLY 211 396 396 GLY GLY A . n A 1 212 ASN 212 397 397 ASN ASN A . n A 1 213 PRO 213 398 398 PRO PRO A . n A 1 214 LEU 214 399 399 LEU LEU A . n A 1 215 PRO 215 400 400 PRO PRO A . n A 1 216 GLU 216 401 401 GLU GLU A . n A 1 217 LEU 217 402 402 LEU LEU A . n A 1 218 LYS 218 403 403 LYS LYS A . n A 1 219 CYS 219 404 404 CYS CYS A . n A 1 220 LEU 220 405 405 LEU LEU A . n A 1 221 LYS 221 406 406 LYS LYS A . n A 1 222 ASP 222 407 407 ASP ASP A . n A 1 223 GLY 223 408 408 GLY GLY A . n A 1 224 THR 224 409 409 THR THR A . n A 1 225 PHE 225 410 410 PHE PHE A . n A 1 226 PRO 226 411 411 PRO PRO A . n A 1 227 LEU 227 412 412 LEU LEU A . n A 1 228 PRO 228 413 413 PRO PRO A . n A 1 229 ILE 229 414 414 ILE ILE A . n A 1 230 GLY 230 415 415 GLY GLY A . n A 1 231 GLU 231 416 416 GLU GLU A . n A 1 232 SER 232 417 417 SER SER A . n A 1 233 VAL 233 418 418 VAL VAL A . n A 1 234 THR 234 419 419 THR THR A . n A 1 235 VAL 235 420 420 VAL VAL A . n A 1 236 THR 236 421 421 THR THR A . n A 1 237 ARG 237 422 422 ARG ARG A . n A 1 238 ASP 238 423 423 ASP ASP A . n A 1 239 LEU 239 424 424 LEU LEU A . n A 1 240 GLU 240 425 425 GLU GLU A . n A 1 241 GLY 241 426 426 GLY GLY A . n A 1 242 THR 242 427 427 THR THR A . n A 1 243 TYR 243 428 428 TYR TYR A . n A 1 244 LEU 244 429 429 LEU LEU A . n A 1 245 CYS 245 430 430 CYS CYS A . n A 1 246 ARG 246 431 431 ARG ARG A . n A 1 247 ALA 247 432 432 ALA ALA A . n A 1 248 ARG 248 433 433 ARG ARG A . n A 1 249 SER 249 434 434 SER SER A . n A 1 250 THR 250 435 435 THR THR A . n A 1 251 GLN 251 436 436 GLN GLN A . n A 1 252 GLY 252 437 437 GLY GLY A . n A 1 253 GLU 253 438 438 GLU GLU A . n A 1 254 VAL 254 439 439 VAL VAL A . n A 1 255 THR 255 440 440 THR THR A . n A 1 256 ARG 256 441 441 ARG ARG A . n A 1 257 GLU 257 442 442 GLU GLU A . n A 1 258 VAL 258 443 443 VAL VAL A . n A 1 259 THR 259 444 444 THR THR A . n A 1 260 VAL 260 445 445 VAL VAL A . n A 1 261 ASN 261 446 446 ASN ASN A . n A 1 262 VAL 262 447 447 VAL VAL A . n A 1 263 LEU 263 448 448 LEU LEU A . n A 1 264 SER 264 449 449 SER SER A . n A 1 265 PRO 265 450 450 PRO PRO A . n B 2 1 ASP 1 1 1 ASP ASP L . n B 2 2 ILE 2 2 2 ILE ILE L . n B 2 3 LEU 3 3 3 LEU LEU L . n B 2 4 LEU 4 4 4 LEU LEU L . n B 2 5 THR 5 5 5 THR THR L . n B 2 6 GLN 6 6 6 GLN GLN L . n B 2 7 SER 7 7 7 SER SER L . n B 2 8 PRO 8 8 8 PRO PRO L . n B 2 9 ALA 9 9 9 ALA ALA L . n B 2 10 ILE 10 10 10 ILE ILE L . n B 2 11 LEU 11 11 11 LEU LEU L . n B 2 12 SER 12 12 12 SER SER L . n B 2 13 VAL 13 13 13 VAL VAL L . n B 2 14 SER 14 14 14 SER SER L . n B 2 15 PRO 15 15 15 PRO PRO L . n B 2 16 GLY 16 16 16 GLY GLY L . n B 2 17 GLU 17 17 17 GLU GLU L . n B 2 18 ARG 18 18 18 ARG ARG L . n B 2 19 VAL 19 19 19 VAL VAL L . n B 2 20 SER 20 20 20 SER SER L . n B 2 21 PHE 21 21 21 PHE PHE L . n B 2 22 SER 22 22 22 SER SER L . n B 2 23 CYS 23 23 23 CYS CYS L . n B 2 24 ARG 24 24 24 ARG ARG L . n B 2 25 ALA 25 25 25 ALA ALA L . n B 2 26 SER 26 26 26 SER SER L . n B 2 27 GLN 27 27 27 GLN GLN L . n B 2 28 SER 28 28 28 SER SER L . n B 2 29 ILE 29 29 29 ILE ILE L . n B 2 30 GLY 30 30 30 GLY GLY L . n B 2 31 THR 31 31 31 THR THR L . n B 2 32 SER 32 32 32 SER SER L . n B 2 33 ILE 33 33 33 ILE ILE L . n B 2 34 HIS 34 34 34 HIS HIS L . n B 2 35 TRP 35 35 35 TRP TRP L . n B 2 36 PHE 36 36 36 PHE PHE L . n B 2 37 GLN 37 37 37 GLN GLN L . n B 2 38 GLN 38 38 38 GLN GLN L . n B 2 39 ARG 39 39 39 ARG ARG L . n B 2 40 ILE 40 40 40 ILE ILE L . n B 2 41 ASN 41 41 41 ASN ASN L . n B 2 42 GLY 42 42 42 GLY GLY L . n B 2 43 SER 43 43 43 SER SER L . n B 2 44 PRO 44 44 44 PRO PRO L . n B 2 45 ARG 45 45 45 ARG ARG L . n B 2 46 LEU 46 46 46 LEU LEU L . n B 2 47 LEU 47 47 47 LEU LEU L . n B 2 48 ILE 48 48 48 ILE ILE L . n B 2 49 GLU 49 49 49 GLU GLU L . n B 2 50 TYR 50 50 50 TYR TYR L . n B 2 51 ALA 51 51 51 ALA ALA L . n B 2 52 SER 52 52 52 SER SER L . n B 2 53 GLU 53 53 53 GLU GLU L . n B 2 54 SER 54 54 54 SER SER L . n B 2 55 ILE 55 55 55 ILE ILE L . n B 2 56 SER 56 56 56 SER SER L . n B 2 57 GLY 57 57 57 GLY GLY L . n B 2 58 ILE 58 58 58 ILE ILE L . n B 2 59 PRO 59 59 59 PRO PRO L . n B 2 60 SER 60 60 60 SER SER L . n B 2 61 ARG 61 61 61 ARG ARG L . n B 2 62 PHE 62 62 62 PHE PHE L . n B 2 63 SER 63 63 63 SER SER L . n B 2 64 GLY 64 64 64 GLY GLY L . n B 2 65 SER 65 65 65 SER SER L . n B 2 66 GLY 66 66 66 GLY GLY L . n B 2 67 SER 67 67 67 SER SER L . n B 2 68 GLY 68 68 68 GLY GLY L . n B 2 69 THR 69 69 69 THR THR L . n B 2 70 ASP 70 70 70 ASP ASP L . n B 2 71 PHE 71 71 71 PHE PHE L . n B 2 72 THR 72 72 72 THR THR L . n B 2 73 LEU 73 73 73 LEU LEU L . n B 2 74 THR 74 74 74 THR THR L . n B 2 75 ILE 75 75 75 ILE ILE L . n B 2 76 ASN 76 76 76 ASN ASN L . n B 2 77 SER 77 77 77 SER SER L . n B 2 78 VAL 78 78 78 VAL VAL L . n B 2 79 GLU 79 79 79 GLU GLU L . n B 2 80 SER 80 80 80 SER SER L . n B 2 81 GLU 81 81 81 GLU GLU L . n B 2 82 ASP 82 82 82 ASP ASP L . n B 2 83 ILE 83 83 83 ILE ILE L . n B 2 84 ALA 84 84 84 ALA ALA L . n B 2 85 ASP 85 85 85 ASP ASP L . n B 2 86 TYR 86 86 86 TYR TYR L . n B 2 87 TYR 87 87 87 TYR TYR L . n B 2 88 CYS 88 88 88 CYS CYS L . n B 2 89 GLN 89 89 89 GLN GLN L . n B 2 90 GLN 90 90 90 GLN GLN L . n B 2 91 SER 91 91 91 SER SER L . n B 2 92 ASN 92 92 92 ASN ASN L . n B 2 93 VAL 93 93 93 VAL VAL L . n B 2 94 TRP 94 94 94 TRP TRP L . n B 2 95 PRO 95 95 95 PRO PRO L . n B 2 96 PHE 96 96 96 PHE PHE L . n B 2 97 THR 97 97 97 THR THR L . n B 2 98 PHE 98 98 98 PHE PHE L . n B 2 99 GLY 99 99 99 GLY GLY L . n B 2 100 SER 100 100 100 SER SER L . n B 2 101 GLY 101 101 101 GLY GLY L . n B 2 102 THR 102 102 102 THR THR L . n B 2 103 LYS 103 103 103 LYS LYS L . n B 2 104 LEU 104 104 104 LEU LEU L . n B 2 105 GLU 105 105 105 GLU GLU L . n B 2 106 ILE 106 106 106 ILE ILE L . n B 2 107 LYS 107 107 107 LYS LYS L . n B 2 108 ARG 108 108 108 ARG ARG L . n B 2 109 ALA 109 109 109 ALA ALA L . n B 2 110 ASP 110 110 110 ASP ASP L . n B 2 111 ALA 111 111 111 ALA ALA L . n B 2 112 ALA 112 112 112 ALA ALA L . n B 2 113 PRO 113 113 113 PRO PRO L . n B 2 114 THR 114 114 114 THR THR L . n B 2 115 VAL 115 115 115 VAL VAL L . n B 2 116 SER 116 116 116 SER SER L . n B 2 117 ILE 117 117 117 ILE ILE L . n B 2 118 PHE 118 118 118 PHE PHE L . n B 2 119 PRO 119 119 119 PRO PRO L . n B 2 120 PRO 120 120 120 PRO PRO L . n B 2 121 SER 121 121 121 SER SER L . n B 2 122 SER 122 122 122 SER SER L . n B 2 123 GLU 123 123 123 GLU GLU L . n B 2 124 GLN 124 124 124 GLN GLN L . n B 2 125 LEU 125 125 125 LEU LEU L . n B 2 126 THR 126 126 126 THR THR L . n B 2 127 SER 127 127 127 SER SER L . n B 2 128 GLY 128 128 128 GLY GLY L . n B 2 129 GLY 129 129 129 GLY GLY L . n B 2 130 ALA 130 130 130 ALA ALA L . n B 2 131 SER 131 131 131 SER SER L . n B 2 132 VAL 132 132 132 VAL VAL L . n B 2 133 VAL 133 133 133 VAL VAL L . n B 2 134 CYS 134 134 134 CYS CYS L . n B 2 135 PHE 135 135 135 PHE PHE L . n B 2 136 LEU 136 136 136 LEU LEU L . n B 2 137 ASN 137 137 137 ASN ASN L . n B 2 138 ASN 138 138 138 ASN ASN L . n B 2 139 PHE 139 139 139 PHE PHE L . n B 2 140 TYR 140 140 140 TYR TYR L . n B 2 141 PRO 141 141 141 PRO PRO L . n B 2 142 LYS 142 142 142 LYS LYS L . n B 2 143 ASP 143 143 143 ASP ASP L . n B 2 144 ILE 144 144 144 ILE ILE L . n B 2 145 ASN 145 145 145 ASN ASN L . n B 2 146 VAL 146 146 146 VAL VAL L . n B 2 147 LYS 147 147 147 LYS LYS L . n B 2 148 TRP 148 148 148 TRP TRP L . n B 2 149 LYS 149 149 149 LYS LYS L . n B 2 150 ILE 150 150 150 ILE ILE L . n B 2 151 ASP 151 151 151 ASP ASP L . n B 2 152 GLY 152 152 152 GLY GLY L . n B 2 153 SER 153 153 153 SER SER L . n B 2 154 GLU 154 154 154 GLU GLU L . n B 2 155 ARG 155 155 155 ARG ARG L . n B 2 156 GLN 156 156 156 GLN GLN L . n B 2 157 ASN 157 157 157 ASN ASN L . n B 2 158 GLY 158 158 158 GLY GLY L . n B 2 159 VAL 159 159 159 VAL VAL L . n B 2 160 LEU 160 160 160 LEU LEU L . n B 2 161 ASN 161 161 161 ASN ASN L . n B 2 162 SER 162 162 162 SER SER L . n B 2 163 TRP 163 163 163 TRP TRP L . n B 2 164 THR 164 164 164 THR THR L . n B 2 165 ASP 165 165 165 ASP ASP L . n B 2 166 GLN 166 166 166 GLN GLN L . n B 2 167 ASP 167 167 167 ASP ASP L . n B 2 168 SER 168 168 168 SER SER L . n B 2 169 LYS 169 169 169 LYS LYS L . n B 2 170 ASP 170 170 170 ASP ASP L . n B 2 171 SER 171 171 171 SER SER L . n B 2 172 THR 172 172 172 THR THR L . n B 2 173 TYR 173 173 173 TYR TYR L . n B 2 174 SER 174 174 174 SER SER L . n B 2 175 MET 175 175 175 MET MET L . n B 2 176 SER 176 176 176 SER SER L . n B 2 177 SER 177 177 177 SER SER L . n B 2 178 THR 178 178 178 THR THR L . n B 2 179 LEU 179 179 179 LEU LEU L . n B 2 180 THR 180 180 180 THR THR L . n B 2 181 LEU 181 181 181 LEU LEU L . n B 2 182 THR 182 182 182 THR THR L . n B 2 183 LYS 183 183 183 LYS LYS L . n B 2 184 ASP 184 184 184 ASP ASP L . n B 2 185 GLU 185 185 185 GLU GLU L . n B 2 186 TYR 186 186 186 TYR TYR L . n B 2 187 GLU 187 187 187 GLU GLU L . n B 2 188 ARG 188 188 188 ARG ARG L . n B 2 189 HIS 189 189 189 HIS HIS L . n B 2 190 ASN 190 190 190 ASN ASN L . n B 2 191 SER 191 191 191 SER SER L . n B 2 192 TYR 192 192 192 TYR TYR L . n B 2 193 THR 193 193 193 THR THR L . n B 2 194 CYS 194 194 194 CYS CYS L . n B 2 195 GLU 195 195 195 GLU GLU L . n B 2 196 ALA 196 196 196 ALA ALA L . n B 2 197 THR 197 197 197 THR THR L . n B 2 198 HIS 198 198 198 HIS HIS L . n B 2 199 LYS 199 199 199 LYS LYS L . n B 2 200 THR 200 200 200 THR THR L . n B 2 201 SER 201 201 201 SER SER L . n B 2 202 THR 202 202 202 THR THR L . n B 2 203 SER 203 203 203 SER SER L . n B 2 204 PRO 204 204 204 PRO PRO L . n B 2 205 ILE 205 205 205 ILE ILE L . n B 2 206 VAL 206 206 206 VAL VAL L . n B 2 207 LYS 207 207 207 LYS LYS L . n B 2 208 SER 208 208 208 SER SER L . n B 2 209 PHE 209 209 209 PHE PHE L . n B 2 210 ASN 210 210 210 ASN ASN L . n B 2 211 ARG 211 211 211 ARG ARG L . n B 2 212 ASN 212 212 212 ASN ASN L . n B 2 213 GLU 213 213 213 GLU GLU L . n B 2 214 CYS 214 214 214 CYS CYS L . n C 3 1 GLU 1 1 1 GLU GLU H . n C 3 2 VAL 2 2 2 VAL VAL H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 LEU 4 4 4 LEU LEU H . n C 3 5 GLN 5 5 5 GLN GLN H . n C 3 6 GLN 6 6 6 GLN GLN H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 PRO 9 9 9 PRO PRO H . n C 3 10 GLU 10 10 10 GLU GLU H . n C 3 11 LEU 11 11 11 LEU LEU H . n C 3 12 VAL 12 12 12 VAL VAL H . n C 3 13 GLN 13 13 13 GLN GLN H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 ALA 16 16 16 ALA ALA H . n C 3 17 SER 17 17 17 SER SER H . n C 3 18 VAL 18 18 18 VAL VAL H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 ILE 20 20 20 ILE ILE H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 LYS 23 23 23 LYS LYS H . n C 3 24 THR 24 24 24 THR THR H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 TYR 27 27 27 TYR TYR H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 PHE 29 29 29 PHE PHE H . n C 3 30 SER 30 30 30 SER SER H . n C 3 31 GLU 31 31 31 GLU GLU H . n C 3 32 PHE 32 32 32 PHE PHE H . n C 3 33 THR 33 33 33 THR THR H . n C 3 34 MET 34 34 34 MET MET H . n C 3 35 HIS 35 35 35 HIS HIS H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 LYS 38 38 38 LYS LYS H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 SER 40 40 40 SER SER H . n C 3 41 HIS 41 41 41 HIS HIS H . n C 3 42 GLY 42 42 42 GLY GLY H . n C 3 43 LYS 43 43 43 LYS LYS H . n C 3 44 SER 44 44 44 SER SER H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 GLU 46 46 46 GLU GLU H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 ILE 48 48 48 ILE ILE H . n C 3 49 GLY 49 49 49 GLY GLY H . n C 3 50 GLY 50 50 50 GLY GLY H . n C 3 51 ILE 51 51 51 ILE ILE H . n C 3 52 ASN 52 52 52 ASN ASN H . n C 3 53 THR 53 53 53 THR THR H . n C 3 54 ILE 54 54 54 ILE ILE H . n C 3 55 ASN 55 55 55 ASN ASN H . n C 3 56 GLY 56 56 56 GLY GLY H . n C 3 57 GLY 57 57 57 GLY GLY H . n C 3 58 SER 58 58 58 SER SER H . n C 3 59 SER 59 59 59 SER SER H . n C 3 60 TYR 60 60 60 TYR TYR H . n C 3 61 LYS 61 61 61 LYS LYS H . n C 3 62 GLN 62 62 62 GLN GLN H . n C 3 63 SER 63 63 63 SER SER H . n C 3 64 PHE 64 64 64 PHE PHE H . n C 3 65 LYS 65 65 65 LYS LYS H . n C 3 66 ASP 66 66 66 ASP ASP H . n C 3 67 LYS 67 67 67 LYS LYS H . n C 3 68 ALA 68 68 68 ALA ALA H . n C 3 69 THR 69 69 69 THR THR H . n C 3 70 LEU 70 70 70 LEU LEU H . n C 3 71 THR 71 71 71 THR THR H . n C 3 72 VAL 72 72 72 VAL VAL H . n C 3 73 ASP 73 73 73 ASP ASP H . n C 3 74 LYS 74 74 74 LYS LYS H . n C 3 75 SER 75 75 75 SER SER H . n C 3 76 SER 76 76 76 SER SER H . n C 3 77 SER 77 77 77 SER SER H . n C 3 78 THR 78 78 78 THR THR H . n C 3 79 ALA 79 79 79 ALA ALA H . n C 3 80 TYR 80 80 80 TYR TYR H . n C 3 81 MET 81 81 81 MET MET H . n C 3 82 GLU 82 82 82 GLU GLU H . n C 3 83 LEU 83 83 83 LEU LEU H . n C 3 84 ASN 84 84 84 ASN ASN H . n C 3 85 SER 85 85 85 SER SER H . n C 3 86 LEU 86 86 86 LEU LEU H . n C 3 87 THR 87 87 87 THR THR H . n C 3 88 SER 88 88 88 SER SER H . n C 3 89 GLU 89 89 89 GLU GLU H . n C 3 90 ASP 90 90 90 ASP ASP H . n C 3 91 SER 91 91 91 SER SER H . n C 3 92 ALA 92 92 92 ALA ALA H . n C 3 93 VAL 93 93 93 VAL VAL H . n C 3 94 TYR 94 94 94 TYR TYR H . n C 3 95 TYR 95 95 95 TYR TYR H . n C 3 96 CYS 96 96 96 CYS CYS H . n C 3 97 ALA 97 97 97 ALA ALA H . n C 3 98 THR 98 98 98 THR THR H . n C 3 99 LYS 99 99 99 LYS LYS H . n C 3 100 GLY 100 100 100 GLY GLY H . n C 3 101 PHE 101 101 101 PHE PHE H . n C 3 102 ALA 102 102 102 ALA ALA H . n C 3 103 TYR 103 103 103 TYR TYR H . n C 3 104 TRP 104 104 104 TRP TRP H . n C 3 105 GLY 105 105 105 GLY GLY H . n C 3 106 GLN 106 106 106 GLN GLN H . n C 3 107 GLY 107 107 107 GLY GLY H . n C 3 108 THR 108 108 108 THR THR H . n C 3 109 LEU 109 109 109 LEU LEU H . n C 3 110 VAL 110 110 110 VAL VAL H . n C 3 111 THR 111 111 111 THR THR H . n C 3 112 VAL 112 112 112 VAL VAL H . n C 3 113 SER 113 113 113 SER SER H . n C 3 114 ALA 114 114 114 ALA ALA H . n C 3 115 ALA 115 115 115 ALA ALA H . n C 3 116 LYS 116 116 116 LYS LYS H . n C 3 117 THR 117 117 117 THR THR H . n C 3 118 THR 118 118 118 THR THR H . n C 3 119 PRO 119 119 119 PRO PRO H . n C 3 120 PRO 120 120 120 PRO PRO H . n C 3 121 SER 121 121 121 SER SER H . n C 3 122 VAL 122 122 122 VAL VAL H . n C 3 123 TYR 123 123 123 TYR TYR H . n C 3 124 PRO 124 124 124 PRO PRO H . n C 3 125 LEU 125 125 125 LEU LEU H . n C 3 126 ALA 126 126 126 ALA ALA H . n C 3 127 PRO 127 127 127 PRO PRO H . n C 3 128 GLY 128 128 ? ? ? H . n C 3 129 SER 129 129 ? ? ? H . n C 3 130 ALA 130 130 ? ? ? H . n C 3 131 ALA 131 131 ? ? ? H . n C 3 132 GLN 132 132 ? ? ? H . n C 3 133 THR 133 133 ? ? ? H . n C 3 134 ASN 134 134 134 ASN ASN H . n C 3 135 SER 135 135 135 SER SER H . n C 3 136 MET 136 136 136 MET MET H . n C 3 137 VAL 137 137 137 VAL VAL H . n C 3 138 THR 138 138 138 THR THR H . n C 3 139 LEU 139 139 139 LEU LEU H . n C 3 140 GLY 140 140 140 GLY GLY H . n C 3 141 CYS 141 141 141 CYS CYS H . n C 3 142 LEU 142 142 142 LEU LEU H . n C 3 143 VAL 143 143 143 VAL VAL H . n C 3 144 LYS 144 144 144 LYS LYS H . n C 3 145 GLY 145 145 145 GLY GLY H . n C 3 146 TYR 146 146 146 TYR TYR H . n C 3 147 PHE 147 147 147 PHE PHE H . n C 3 148 PRO 148 148 148 PRO PRO H . n C 3 149 GLU 149 149 149 GLU GLU H . n C 3 150 PRO 150 150 150 PRO PRO H . n C 3 151 VAL 151 151 151 VAL VAL H . n C 3 152 THR 152 152 152 THR THR H . n C 3 153 VAL 153 153 153 VAL VAL H . n C 3 154 THR 154 154 154 THR THR H . n C 3 155 TRP 155 155 155 TRP TRP H . n C 3 156 ASN 156 156 156 ASN ASN H . n C 3 157 SER 157 157 157 SER SER H . n C 3 158 GLY 158 158 158 GLY GLY H . n C 3 159 SER 159 159 159 SER SER H . n C 3 160 LEU 160 160 160 LEU LEU H . n C 3 161 SER 161 161 161 SER SER H . n C 3 162 SER 162 162 162 SER SER H . n C 3 163 GLY 163 163 163 GLY GLY H . n C 3 164 VAL 164 164 164 VAL VAL H . n C 3 165 HIS 165 165 165 HIS HIS H . n C 3 166 THR 166 166 166 THR THR H . n C 3 167 PHE 167 167 167 PHE PHE H . n C 3 168 PRO 168 168 168 PRO PRO H . n C 3 169 ALA 169 169 169 ALA ALA H . n C 3 170 VAL 170 170 170 VAL VAL H . n C 3 171 LEU 171 171 171 LEU LEU H . n C 3 172 GLN 172 172 172 GLN GLN H . n C 3 173 SER 173 173 173 SER SER H . n C 3 174 ASP 174 174 174 ASP ASP H . n C 3 175 LEU 175 175 175 LEU LEU H . n C 3 176 TYR 176 176 176 TYR TYR H . n C 3 177 THR 177 177 177 THR THR H . n C 3 178 LEU 178 178 178 LEU LEU H . n C 3 179 SER 179 179 179 SER SER H . n C 3 180 SER 180 180 180 SER SER H . n C 3 181 SER 181 181 181 SER SER H . n C 3 182 VAL 182 182 182 VAL VAL H . n C 3 183 THR 183 183 183 THR THR H . n C 3 184 VAL 184 184 184 VAL VAL H . n C 3 185 PRO 185 185 185 PRO PRO H . n C 3 186 SER 186 186 186 SER SER H . n C 3 187 SER 187 187 187 SER SER H . n C 3 188 THR 188 188 188 THR THR H . n C 3 189 TRP 189 189 189 TRP TRP H . n C 3 190 PRO 190 190 190 PRO PRO H . n C 3 191 SER 191 191 191 SER SER H . n C 3 192 GLU 192 192 192 GLU GLU H . n C 3 193 THR 193 193 193 THR THR H . n C 3 194 VAL 194 194 194 VAL VAL H . n C 3 195 THR 195 195 195 THR THR H . n C 3 196 CYS 196 196 196 CYS CYS H . n C 3 197 ASN 197 197 197 ASN ASN H . n C 3 198 VAL 198 198 198 VAL VAL H . n C 3 199 ALA 199 199 199 ALA ALA H . n C 3 200 HIS 200 200 200 HIS HIS H . n C 3 201 PRO 201 201 201 PRO PRO H . n C 3 202 ALA 202 202 202 ALA ALA H . n C 3 203 SER 203 203 203 SER SER H . n C 3 204 SER 204 204 204 SER SER H . n C 3 205 THR 205 205 205 THR THR H . n C 3 206 LYS 206 206 206 LYS LYS H . n C 3 207 VAL 207 207 207 VAL VAL H . n C 3 208 ASP 208 208 208 ASP ASP H . n C 3 209 LYS 209 209 209 LYS LYS H . n C 3 210 LYS 210 210 210 LYS LYS H . n C 3 211 ILE 211 211 211 ILE ILE H . n C 3 212 VAL 212 212 212 VAL VAL H . n C 3 213 PRO 213 213 213 PRO PRO H . n C 3 214 ARG 214 214 214 ARG ARG H . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 4 NAG 1 1240 1240 NAG NAG A . E 5 FUC 2 1241 1241 FUC FUC A . F 4 NAG 1 1269 1269 NAG NAG A . G 4 NAG 1 1358 1358 NAG NAG A . H 6 SO4 1 2000 2000 SO4 SO4 A . I 6 SO4 1 2000 2000 SO4 SO4 L . J 7 ZN 1 2001 2001 ZN ZN L . K 7 ZN 1 2002 2002 ZN ZN L . L 8 TRS 1 2003 2003 TRS TRS L . M 8 TRS 1 2004 2004 TRS TRS L . N 9 HOH 1 3001 3001 HOH HOH A . N 9 HOH 2 3002 3002 HOH HOH A . N 9 HOH 3 3003 3003 HOH HOH A . N 9 HOH 4 3004 3004 HOH HOH A . N 9 HOH 5 3005 3005 HOH HOH A . N 9 HOH 6 3006 3006 HOH HOH A . N 9 HOH 7 3007 3007 HOH HOH A . N 9 HOH 8 3008 3008 HOH HOH A . N 9 HOH 9 3009 3009 HOH HOH A . N 9 HOH 10 3010 3010 HOH HOH A . N 9 HOH 11 3011 3011 HOH HOH A . N 9 HOH 12 3012 3012 HOH HOH A . N 9 HOH 13 3013 3013 HOH HOH A . N 9 HOH 14 3014 3014 HOH HOH A . N 9 HOH 15 3015 3015 HOH HOH A . N 9 HOH 16 3016 3016 HOH HOH A . N 9 HOH 17 3017 3017 HOH HOH A . N 9 HOH 18 3018 3018 HOH HOH A . N 9 HOH 19 3019 3019 HOH HOH A . N 9 HOH 20 3020 3020 HOH HOH A . N 9 HOH 21 3021 3021 HOH HOH A . N 9 HOH 22 3022 3022 HOH HOH A . N 9 HOH 23 3023 3023 HOH HOH A . N 9 HOH 24 3024 3024 HOH HOH A . N 9 HOH 25 3025 3025 HOH HOH A . N 9 HOH 26 3026 3026 HOH HOH A . N 9 HOH 27 3027 3027 HOH HOH A . N 9 HOH 28 3028 3028 HOH HOH A . N 9 HOH 29 3029 3029 HOH HOH A . N 9 HOH 30 3030 3030 HOH HOH A . N 9 HOH 31 3031 3031 HOH HOH A . N 9 HOH 32 3032 3032 HOH HOH A . N 9 HOH 33 3033 3033 HOH HOH A . N 9 HOH 34 3034 3034 HOH HOH A . N 9 HOH 35 3035 3035 HOH HOH A . N 9 HOH 36 3036 3036 HOH HOH A . N 9 HOH 37 3037 3037 HOH HOH A . N 9 HOH 38 3038 3038 HOH HOH A . N 9 HOH 39 3039 3039 HOH HOH A . N 9 HOH 40 3040 3040 HOH HOH A . N 9 HOH 41 3041 3041 HOH HOH A . N 9 HOH 42 3042 3042 HOH HOH A . N 9 HOH 43 3043 3043 HOH HOH A . N 9 HOH 44 3044 3044 HOH HOH A . N 9 HOH 45 3045 3045 HOH HOH A . N 9 HOH 46 3046 3046 HOH HOH A . N 9 HOH 47 3047 3047 HOH HOH A . N 9 HOH 48 3048 3048 HOH HOH A . N 9 HOH 49 3049 3049 HOH HOH A . N 9 HOH 50 3050 3050 HOH HOH A . N 9 HOH 51 3051 3051 HOH HOH A . N 9 HOH 52 3052 3052 HOH HOH A . N 9 HOH 53 3053 3053 HOH HOH A . N 9 HOH 54 3054 3054 HOH HOH A . N 9 HOH 55 3055 3055 HOH HOH A . N 9 HOH 56 3056 3056 HOH HOH A . N 9 HOH 57 3057 3057 HOH HOH A . N 9 HOH 58 3058 3058 HOH HOH A . N 9 HOH 59 3059 3059 HOH HOH A . N 9 HOH 60 3060 3060 HOH HOH A . N 9 HOH 61 3061 3061 HOH HOH A . N 9 HOH 62 3062 3062 HOH HOH A . N 9 HOH 63 3063 3063 HOH HOH A . N 9 HOH 64 3064 3064 HOH HOH A . N 9 HOH 65 3065 3065 HOH HOH A . N 9 HOH 66 3066 3066 HOH HOH A . N 9 HOH 67 3067 3067 HOH HOH A . N 9 HOH 68 3068 3068 HOH HOH A . N 9 HOH 69 3069 3069 HOH HOH A . N 9 HOH 70 3070 3070 HOH HOH A . N 9 HOH 71 3071 3071 HOH HOH A . N 9 HOH 72 3072 3072 HOH HOH A . N 9 HOH 73 3073 3073 HOH HOH A . N 9 HOH 74 3074 3074 HOH HOH A . N 9 HOH 75 3075 3075 HOH HOH A . N 9 HOH 76 3076 3076 HOH HOH A . N 9 HOH 77 3077 3077 HOH HOH A . N 9 HOH 78 3078 3078 HOH HOH A . N 9 HOH 79 3079 3079 HOH HOH A . N 9 HOH 80 3080 3080 HOH HOH A . N 9 HOH 81 3081 3081 HOH HOH A . N 9 HOH 82 3082 3082 HOH HOH A . N 9 HOH 83 3083 3083 HOH HOH A . N 9 HOH 84 3084 3084 HOH HOH A . N 9 HOH 85 3085 3085 HOH HOH A . N 9 HOH 86 3086 3086 HOH HOH A . N 9 HOH 87 3087 3087 HOH HOH A . N 9 HOH 88 3088 3088 HOH HOH A . N 9 HOH 89 3089 3089 HOH HOH A . N 9 HOH 90 3090 3090 HOH HOH A . N 9 HOH 91 3091 3091 HOH HOH A . N 9 HOH 92 3092 3092 HOH HOH A . N 9 HOH 93 3093 3093 HOH HOH A . N 9 HOH 94 3094 3094 HOH HOH A . N 9 HOH 95 3095 3095 HOH HOH A . N 9 HOH 96 3096 3096 HOH HOH A . N 9 HOH 97 3097 3097 HOH HOH A . N 9 HOH 98 3098 3098 HOH HOH A . N 9 HOH 99 3099 3099 HOH HOH A . N 9 HOH 100 3100 3100 HOH HOH A . N 9 HOH 101 3101 3101 HOH HOH A . N 9 HOH 102 3102 3102 HOH HOH A . N 9 HOH 103 3103 3103 HOH HOH A . N 9 HOH 104 3104 3104 HOH HOH A . N 9 HOH 105 3105 3105 HOH HOH A . N 9 HOH 106 3106 3106 HOH HOH A . N 9 HOH 107 3107 3107 HOH HOH A . N 9 HOH 108 3108 3108 HOH HOH A . N 9 HOH 109 3109 3109 HOH HOH A . N 9 HOH 110 3110 3110 HOH HOH A . N 9 HOH 111 3111 3111 HOH HOH A . N 9 HOH 112 3112 3112 HOH HOH A . N 9 HOH 113 3113 3113 HOH HOH A . N 9 HOH 114 3114 3114 HOH HOH A . N 9 HOH 115 3115 3115 HOH HOH A . N 9 HOH 116 3116 3116 HOH HOH A . N 9 HOH 117 3117 3117 HOH HOH A . N 9 HOH 118 3118 3118 HOH HOH A . N 9 HOH 119 3119 3119 HOH HOH A . N 9 HOH 120 3120 3120 HOH HOH A . N 9 HOH 121 3121 3121 HOH HOH A . N 9 HOH 122 3122 3122 HOH HOH A . N 9 HOH 123 3123 3123 HOH HOH A . N 9 HOH 124 3124 3124 HOH HOH A . N 9 HOH 125 3125 3125 HOH HOH A . N 9 HOH 126 3126 3126 HOH HOH A . N 9 HOH 127 3127 3127 HOH HOH A . O 9 HOH 1 3001 3001 HOH HOH L . O 9 HOH 2 3002 3002 HOH HOH L . O 9 HOH 3 3003 3003 HOH HOH L . O 9 HOH 4 3004 3004 HOH HOH L . O 9 HOH 5 3005 3005 HOH HOH L . O 9 HOH 6 3006 3006 HOH HOH L . O 9 HOH 7 3007 3007 HOH HOH L . O 9 HOH 8 3008 3008 HOH HOH L . O 9 HOH 9 3009 3009 HOH HOH L . O 9 HOH 10 3010 3010 HOH HOH L . O 9 HOH 11 3011 3011 HOH HOH L . O 9 HOH 12 3012 3012 HOH HOH L . O 9 HOH 13 3013 3013 HOH HOH L . O 9 HOH 14 3014 3014 HOH HOH L . O 9 HOH 15 3015 3015 HOH HOH L . O 9 HOH 16 3016 3016 HOH HOH L . O 9 HOH 17 3017 3017 HOH HOH L . O 9 HOH 18 3018 3018 HOH HOH L . O 9 HOH 19 3019 3019 HOH HOH L . O 9 HOH 20 3020 3020 HOH HOH L . O 9 HOH 21 3021 3021 HOH HOH L . O 9 HOH 22 3022 3022 HOH HOH L . O 9 HOH 23 3023 3023 HOH HOH L . O 9 HOH 24 3024 3024 HOH HOH L . O 9 HOH 25 3025 3025 HOH HOH L . O 9 HOH 26 3026 3026 HOH HOH L . O 9 HOH 27 3027 3027 HOH HOH L . O 9 HOH 28 3028 3028 HOH HOH L . O 9 HOH 29 3029 3029 HOH HOH L . O 9 HOH 30 3030 3030 HOH HOH L . O 9 HOH 31 3031 3031 HOH HOH L . O 9 HOH 32 3032 3032 HOH HOH L . O 9 HOH 33 3033 3033 HOH HOH L . O 9 HOH 34 3034 3034 HOH HOH L . O 9 HOH 35 3035 3035 HOH HOH L . O 9 HOH 36 3036 3036 HOH HOH L . O 9 HOH 37 3037 3037 HOH HOH L . O 9 HOH 38 3038 3038 HOH HOH L . O 9 HOH 39 3039 3039 HOH HOH L . O 9 HOH 40 3040 3040 HOH HOH L . O 9 HOH 41 3041 3041 HOH HOH L . O 9 HOH 42 3042 3042 HOH HOH L . O 9 HOH 43 3043 3043 HOH HOH L . O 9 HOH 44 3044 3044 HOH HOH L . O 9 HOH 45 3045 3045 HOH HOH L . O 9 HOH 46 3046 3046 HOH HOH L . O 9 HOH 47 3047 3047 HOH HOH L . O 9 HOH 48 3048 3048 HOH HOH L . O 9 HOH 49 3049 3049 HOH HOH L . O 9 HOH 50 3050 3050 HOH HOH L . O 9 HOH 51 3051 3051 HOH HOH L . O 9 HOH 52 3052 3052 HOH HOH L . O 9 HOH 53 3053 3053 HOH HOH L . O 9 HOH 54 3054 3054 HOH HOH L . O 9 HOH 55 3055 3055 HOH HOH L . O 9 HOH 56 3056 3056 HOH HOH L . O 9 HOH 57 3057 3057 HOH HOH L . O 9 HOH 58 3058 3058 HOH HOH L . O 9 HOH 59 3059 3059 HOH HOH L . O 9 HOH 60 3060 3060 HOH HOH L . O 9 HOH 61 3061 3061 HOH HOH L . O 9 HOH 62 3062 3062 HOH HOH L . O 9 HOH 63 3063 3063 HOH HOH L . O 9 HOH 64 3064 3064 HOH HOH L . O 9 HOH 65 3065 3065 HOH HOH L . O 9 HOH 66 3066 3066 HOH HOH L . O 9 HOH 67 3067 3067 HOH HOH L . O 9 HOH 68 3068 3068 HOH HOH L . O 9 HOH 69 3069 3069 HOH HOH L . O 9 HOH 70 3070 3070 HOH HOH L . O 9 HOH 71 3071 3071 HOH HOH L . O 9 HOH 72 3072 3072 HOH HOH L . O 9 HOH 73 3073 3073 HOH HOH L . O 9 HOH 74 3074 3074 HOH HOH L . O 9 HOH 75 3075 3075 HOH HOH L . O 9 HOH 76 3076 3076 HOH HOH L . O 9 HOH 77 3077 3077 HOH HOH L . O 9 HOH 78 3078 3078 HOH HOH L . O 9 HOH 79 3079 3079 HOH HOH L . O 9 HOH 80 3080 3080 HOH HOH L . O 9 HOH 81 3081 3081 HOH HOH L . O 9 HOH 82 3082 3082 HOH HOH L . O 9 HOH 83 3083 3083 HOH HOH L . O 9 HOH 84 3084 3084 HOH HOH L . O 9 HOH 85 3085 3085 HOH HOH L . O 9 HOH 86 3086 3086 HOH HOH L . P 9 HOH 1 3001 3001 HOH HOH H . P 9 HOH 2 3002 3002 HOH HOH H . P 9 HOH 3 3003 3003 HOH HOH H . P 9 HOH 4 3004 3004 HOH HOH H . P 9 HOH 5 3005 3005 HOH HOH H . P 9 HOH 6 3006 3006 HOH HOH H . P 9 HOH 7 3007 3007 HOH HOH H . P 9 HOH 8 3008 3008 HOH HOH H . P 9 HOH 9 3009 3009 HOH HOH H . P 9 HOH 10 3010 3010 HOH HOH H . P 9 HOH 11 3011 3011 HOH HOH H . P 9 HOH 12 3012 3012 HOH HOH H . P 9 HOH 13 3013 3013 HOH HOH H . P 9 HOH 14 3014 3014 HOH HOH H . P 9 HOH 15 3015 3015 HOH HOH H . P 9 HOH 16 3016 3016 HOH HOH H . P 9 HOH 17 3017 3017 HOH HOH H . P 9 HOH 18 3018 3018 HOH HOH H . P 9 HOH 19 3019 3019 HOH HOH H . P 9 HOH 20 3020 3020 HOH HOH H . P 9 HOH 21 3021 3021 HOH HOH H . P 9 HOH 22 3022 3022 HOH HOH H . P 9 HOH 23 3023 3023 HOH HOH H . P 9 HOH 24 3024 3024 HOH HOH H . P 9 HOH 25 3025 3025 HOH HOH H . P 9 HOH 26 3026 3026 HOH HOH H . P 9 HOH 27 3027 3027 HOH HOH H . P 9 HOH 28 3028 3028 HOH HOH H . P 9 HOH 29 3029 3029 HOH HOH H . P 9 HOH 30 3030 3030 HOH HOH H . P 9 HOH 31 3031 3031 HOH HOH H . P 9 HOH 32 3032 3032 HOH HOH H . P 9 HOH 33 3033 3033 HOH HOH H . P 9 HOH 34 3034 3034 HOH HOH H . P 9 HOH 35 3035 3035 HOH HOH H . P 9 HOH 36 3036 3036 HOH HOH H . P 9 HOH 37 3037 3037 HOH HOH H . P 9 HOH 38 3038 3038 HOH HOH H . P 9 HOH 39 3039 3039 HOH HOH H . P 9 HOH 40 3040 3040 HOH HOH H . P 9 HOH 41 3041 3041 HOH HOH H . P 9 HOH 42 3042 3042 HOH HOH H . P 9 HOH 43 3043 3043 HOH HOH H . P 9 HOH 44 3044 3044 HOH HOH H . P 9 HOH 45 3045 3045 HOH HOH H . P 9 HOH 46 3046 3046 HOH HOH H . P 9 HOH 47 3047 3047 HOH HOH H . P 9 HOH 48 3048 3048 HOH HOH H . P 9 HOH 49 3049 3049 HOH HOH H . P 9 HOH 50 3050 3050 HOH HOH H . P 9 HOH 51 3051 3051 HOH HOH H . P 9 HOH 52 3052 3052 HOH HOH H . P 9 HOH 53 3053 3053 HOH HOH H . P 9 HOH 54 3054 3054 HOH HOH H . P 9 HOH 55 3055 3055 HOH HOH H . P 9 HOH 56 3056 3056 HOH HOH H . P 9 HOH 57 3057 3057 HOH HOH H . P 9 HOH 58 3058 3058 HOH HOH H . P 9 HOH 59 3059 3059 HOH HOH H . P 9 HOH 60 3060 3060 HOH HOH H . P 9 HOH 61 3061 3061 HOH HOH H . P 9 HOH 62 3062 3062 HOH HOH H . P 9 HOH 63 3063 3063 HOH HOH H . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 84 A ASN 269 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 173 A ASN 358 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 55 A ASN 240 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details trimeric _pdbx_struct_assembly.oligomeric_count 3 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_special_symmetry.id _pdbx_struct_special_symmetry.PDB_model_num _pdbx_struct_special_symmetry.auth_asym_id _pdbx_struct_special_symmetry.auth_comp_id _pdbx_struct_special_symmetry.auth_seq_id _pdbx_struct_special_symmetry.PDB_ins_code _pdbx_struct_special_symmetry.label_asym_id _pdbx_struct_special_symmetry.label_comp_id _pdbx_struct_special_symmetry.label_seq_id 1 1 L ZN 2002 ? K ZN . 2 1 L HOH 3081 ? O HOH . # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 N ? B ASP 1 ? L ASP 1 ? 1_555 ZN ? J ZN . ? L ZN 2001 ? 1_555 O ? B ASP 1 ? L ASP 1 ? 1_555 79.1 ? 2 OE1 ? B GLU 185 ? L GLU 185 ? 1_555 ZN ? K ZN . ? L ZN 2002 ? 1_555 O ? O HOH . ? L HOH 3082 ? 1_555 73.3 ? 3 OE1 ? B GLU 185 ? L GLU 185 ? 1_555 ZN ? K ZN . ? L ZN 2002 ? 1_555 O ? O HOH . ? L HOH 3081 ? 1_555 92.7 ? 4 O ? O HOH . ? L HOH 3082 ? 1_555 ZN ? K ZN . ? L ZN 2002 ? 1_555 O ? O HOH . ? L HOH 3081 ? 1_555 117.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2007-10-16 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' Advisory 2 2 'Structure model' 'Version format compliance' # loop_ _pdbx_refine_tls.id _pdbx_refine_tls.details _pdbx_refine_tls.method _pdbx_refine_tls.origin_x _pdbx_refine_tls.origin_y _pdbx_refine_tls.origin_z _pdbx_refine_tls.T[1][1] _pdbx_refine_tls.T[2][2] _pdbx_refine_tls.T[3][3] _pdbx_refine_tls.T[1][2] _pdbx_refine_tls.T[1][3] _pdbx_refine_tls.T[2][3] _pdbx_refine_tls.L[1][1] _pdbx_refine_tls.L[2][2] _pdbx_refine_tls.L[3][3] _pdbx_refine_tls.L[1][2] _pdbx_refine_tls.L[1][3] _pdbx_refine_tls.L[2][3] _pdbx_refine_tls.S[1][1] _pdbx_refine_tls.S[1][2] _pdbx_refine_tls.S[1][3] _pdbx_refine_tls.S[2][1] _pdbx_refine_tls.S[2][2] _pdbx_refine_tls.S[2][3] _pdbx_refine_tls.S[3][1] _pdbx_refine_tls.S[3][2] _pdbx_refine_tls.S[3][3] _pdbx_refine_tls.pdbx_refine_id 1 ? refined -64.1561 10.1172 62.9419 -0.3070 -0.1784 -0.1192 -0.1357 0.0182 -0.0611 3.7888 3.2977 5.4443 -2.2024 2.5848 -1.6336 -0.1355 -0.0256 0.6613 -0.0865 0.0192 -0.0697 -0.7092 0.2389 0.1163 'X-RAY DIFFRACTION' 2 ? refined -64.1176 -12.6262 65.1816 -0.2670 -0.2413 -0.3925 0.0005 0.0304 -0.0516 9.4823 3.7392 5.3914 2.5616 1.7370 -0.1313 0.0955 -0.2652 0.0824 -0.0955 -0.1383 0.3002 0.4706 0.1581 0.0429 'X-RAY DIFFRACTION' 3 ? refined -93.1729 2.2572 39.7835 0.0744 -0.2237 0.2564 0.0958 -0.3244 0.0040 8.4633 13.1294 3.8139 7.6795 1.7386 0.2689 0.1965 0.4445 0.1005 -0.9982 0.2312 1.7280 0.4170 -0.4469 -0.4278 'X-RAY DIFFRACTION' 4 ? refined -81.3958 -9.2003 38.8526 0.2676 -0.1861 0.2620 0.2103 0.0077 -0.1277 5.2771 15.2083 10.2509 2.2967 2.2505 -4.9246 0.2122 0.8065 -0.8230 -2.5219 -0.6196 -1.1087 0.8045 0.4581 0.4073 'X-RAY DIFFRACTION' 5 ? refined -43.1146 -23.9881 5.8955 -0.1634 0.0079 -0.2157 -0.0171 0.0834 0.0739 4.4057 6.2101 8.9468 3.9093 2.8053 4.8531 0.1095 0.1975 -0.1447 -0.0038 0.0842 -0.3011 -0.0745 0.7120 -0.1937 'X-RAY DIFFRACTION' 6 ? refined -38.6333 -1.6353 39.7885 0.4421 -0.2261 -0.0754 -0.2500 0.0305 0.0229 4.6420 1.1810 39.5370 0.9123 1.5822 5.5133 -0.4793 -0.2472 0.7968 -1.1852 0.0738 -0.0566 -3.8188 1.2155 0.4055 'X-RAY DIFFRACTION' 7 ? refined -47.8775 -6.4655 80.8953 -0.3495 0.4818 -0.2809 0.0297 -0.0340 -0.0217 5.9026 1.1067 8.6028 1.1004 -5.5781 0.5024 0.0460 -1.3023 -0.1788 0.1845 -0.0556 0.0272 -0.0564 1.4273 0.0096 'X-RAY DIFFRACTION' # loop_ _pdbx_refine_tls_group.id _pdbx_refine_tls_group.refine_tls_id _pdbx_refine_tls_group.beg_auth_asym_id _pdbx_refine_tls_group.beg_auth_seq_id _pdbx_refine_tls_group.beg_label_asym_id _pdbx_refine_tls_group.beg_label_seq_id _pdbx_refine_tls_group.end_auth_asym_id _pdbx_refine_tls_group.end_auth_seq_id _pdbx_refine_tls_group.end_label_asym_id _pdbx_refine_tls_group.end_label_seq_id _pdbx_refine_tls_group.selection _pdbx_refine_tls_group.pdbx_refine_id _pdbx_refine_tls_group.selection_details 1 1 L 1 B 1 L 108 B 108 ? 'X-RAY DIFFRACTION' ? 2 2 H 1 C 1 H 114 C 114 ? 'X-RAY DIFFRACTION' ? 3 3 L 109 B 109 L 213 B 213 ? 'X-RAY DIFFRACTION' ? 4 4 H 115 C 115 H 213 C 213 ? 'X-RAY DIFFRACTION' ? 5 5 A 186 A 1 A 282 A 97 ? 'X-RAY DIFFRACTION' ? 6 6 A 283 A 98 A 366 A 181 ? 'X-RAY DIFFRACTION' ? 7 7 A 367 A 182 A 450 A 265 ? 'X-RAY DIFFRACTION' ? # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.2.0019 ? 1 HKL-2000 'data collection' . ? 2 HKL-2000 'data reduction' . ? 3 HKL-2000 'data scaling' . ? 4 MOLREP phasing . ? 5 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 GLN A 321 ? ? 68.36 112.31 2 1 LEU A 329 ? ? -163.23 112.06 3 1 CYS A 376 ? ? -158.03 79.68 4 1 CYS A 392 ? ? -166.40 112.75 5 1 ALA L 51 ? ? 74.57 -62.63 6 1 GLU L 187 ? ? -76.12 21.02 7 1 LYS H 43 ? ? 66.90 62.27 8 1 ASP H 66 ? ? 83.02 -33.29 9 1 ALA H 92 ? ? -174.56 -178.95 10 1 SER H 135 ? ? 51.94 70.45 11 1 CYS H 141 ? ? -160.05 107.47 12 1 PRO H 190 ? ? -89.29 33.04 13 1 LYS H 206 ? ? -152.87 80.80 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 H GLY 128 ? C GLY 128 2 1 Y 1 H SER 129 ? C SER 129 3 1 Y 1 H ALA 130 ? C ALA 130 4 1 Y 1 H ALA 131 ? C ALA 131 5 1 Y 1 H GLN 132 ? C GLN 132 6 1 Y 1 H THR 133 ? C THR 133 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 N-ACETYL-D-GLUCOSAMINE NAG 5 ALPHA-L-FUCOSE FUC 6 'SULFATE ION' SO4 7 'ZINC ION' ZN 8 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL TRS 9 water HOH #