data_2J6E # _entry.id 2J6E # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2J6E PDBE EBI-30026 WWPDB D_1290030026 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 1AJ7 unspecified ;IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY ; PDB 1AQK unspecified 'THREE-DIMENSIONAL STRUCTURE OF A HUMAN FAB WITH HIGH AFFINITY FOR TETANUS TOXOID' PDB 1D5B unspecified 'UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY' PDB 1D5I unspecified 'UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY' PDB 1D6V unspecified 'CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION' PDB 1DN2 unspecified 'FC FRAGMENT OF HUMAN IGG1 IN COMPLEX WITH AN ENGINEERED 13 RESIDUE PEPTIDE DCAWHLGELVWCT-NH2' PDB 1E4K unspecified 'CRYSTAL STRUCTURE OF SOLUBLE HUMAN IGG1 FC FRAGMENT-FC-GAMMA RECEPTOR III COMPLEX' PDB 1FC1 unspecified 'FC FRAGMENT (IGG1 CLASS)' PDB 1FC2 unspecified . PDB 1FCC unspecified . PDB 1H3T unspecified 'STRUCTURAL ANALYSIS OF HUMAN IGG-FC GLYCOFORMS REVEALS A CORRELATION BETWEEN GLYCOSYLATION AND STRUCTURAL INTEGRITY' PDB 1H3U unspecified 'STRUCTURAL ANALYSIS OF HUMAN IGG-FC GLYCOFORMS REVEALS A CORRELATION BETWEEN GLYCOSYLATION AND STRUCTURAL INTEGRITY' PDB 1H3V unspecified 'STRUCTURAL ANALYSIS OF HUMAN IGG-FC GLYCOFORMS REVEALS A CORRELATION BETWEEN GLYCOSYLATION AND STRUCTURAL INTEGRITY' PDB 1H3W unspecified 'STRUCTURAL ANALYSIS OF HUMAN IGG-FC GLYCOFORMS REVEALS A CORRELATION BETWEEN GLYCOSYLATION AND STRUCTURAL INTEGRITY' PDB 1H3Y unspecified 'CRYSTAL STRUCTURE OF A HUMAN IGG1 FC- FRAGMENT,HIGH SALTCONDITION' PDB 1HZH unspecified ;CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROADAND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: ATEMPLATE FOR HIV VACCINE DESIGN ; PDB 1I7Z unspecified 'ANTIBODY GNC92H2 BOUND TO LIGAND' PDB 1IIS unspecified 'CRYSTAL STRUCTURE OF A HUMAN FCG RECEPTOR IN COMPLEX WITHAN FC FRAGMENT OF IGG1 ( ORTHORHOMBIC)' PDB 1IIX unspecified 'CRYSTAL STRUCTURE OF A HUMAN FCG RECEPTOR IN COMPLEX WITHAN FC FRAGMENT OF IGG1 ( HEXAGONAL)' PDB 1L6X unspecified 'FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OFTHE B-DOMAIN FROM PROTEIN A CALLED Z34C' PDB 1N7M unspecified 'GERMLINE 7G12 WITH N-METHYLMESOPORPHYRIN' PDB 1OQX unspecified 'G-2 GLYCOVARIANT OF HUMAN IGG FC BOUND TO MINIMIZED VERSIONOF PROTEIN A CALLED Z34C' PDB 1T83 unspecified 'CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR INCOMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)' PDB 2IWG unspecified T.B.C PDB 2RCS unspecified 'IMMUNOGLOBULIN 48G7 GERMLINE FAB - AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2J6E _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2006-09-28 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Duquerroy, S.' 1 'Stura, E.A.' 2 'Bressanelli, S.' 3 'Browne, H.' 4 'Beale, D.' 5 'Hamon, M.' 6 'Casali, P.' 7 'Vaney, M.-C.' 8 'Rey, F.A.' 9 'Sutton, B.J.' 10 'Taussig, M.J.' 11 # _citation.id primary _citation.title ;Crystal Structure of a Human Autoimmune Complex between Igm Rheumatoid Factor Rf61 and Igg1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation. ; _citation.journal_abbrev J.Mol.Biol. _citation.journal_volume 368 _citation.page_first 1321 _citation.page_last ? _citation.year 2007 _citation.journal_id_ASTM JMOBAK _citation.country UK _citation.journal_id_ISSN 0022-2836 _citation.journal_id_CSD 0070 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 17395205 _citation.pdbx_database_id_DOI 10.1016/J.JMB.2007.02.085 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Duquerroy, S.' 1 primary 'Stura, E.A.' 2 primary 'Bressanelli, S.' 3 primary 'Fabiane, S.M.' 4 primary 'Vaney, M.-C.' 5 primary 'Beale, D.' 6 primary 'Hamon, M.' 7 primary 'Casali, P.' 8 primary 'Rey, F.A.' 9 primary 'Sutton, B.J.' 10 primary 'Taussig, M.J.' 11 # _cell.entry_id 2J6E _cell.length_a 241.980 _cell.length_b 75.610 _cell.length_c 102.400 _cell.angle_alpha 90.00 _cell.angle_beta 91.13 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 2J6E _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'IG GAMMA-1 CHAIN C REGION' 26140.613 2 ? ? 'FC DOMAIN, RESIDUES 99-330' ? 2 polymer man IGM 24831.891 2 ? ? ? ? 3 polymer man IGM 24757.652 2 ? ? ? ? 4 non-polymer syn 'CADMIUM ION' 112.411 1 ? ? ? ? 5 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 6 non-polymer syn 'CACODYLATE ION' 136.989 1 ? ? ? ? 7 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 6 ? ? ? ? 8 non-polymer syn 'ACETATE ION' 59.044 4 ? ? ? ? 9 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 7 ? ? ? ? 10 non-polymer man BETA-L-FUCOSE 164.156 2 ? ? ? ? 11 non-polymer man BETA-D-MANNOSE 180.156 4 ? ? ? ? 12 non-polymer man ALPHA-D-MANNOSE 180.156 2 ? ? ? ? 13 non-polymer man '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' 221.208 1 ? ? ? ? 14 non-polymer man BETA-D-GALACTOSE 180.156 2 ? ? ? ? 15 water nat water 18.015 84 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 IGG1 2 'FAB HEAVY CHAIN' 3 'FAB LIGHT CHAIN' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;EPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEEPEVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPS DIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; ;EPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEEPEVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPS DIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; A,B ? 2 'polypeptide(L)' no no ;LLLVAAPRWLSQLQLQESGPGLVKPSETLSLTCTVSGGSISRGSHYWGWIRQPPGKGLEWIGSIYYSGNTYFNPSLKSRV TISVDTSKNQFSLKLSSVTAADTAVYYCARLGPDDYTLDGMDVWGQGTTVTVSSGSASAPTLFPLVSCDTSSVAVGCLAQ DFLPDSITFSWKYKNNSDISSTRGFPSVLRGGKYAATSQVLLPSKDVMQGTDEHVVCKVQHPNGNKEKNVP ; ;LLLVAAPRWLSQLQLQESGPGLVKPSETLSLTCTVSGGSISRGSHYWGWIRQPPGKGLEWIGSIYYSGNTYFNPSLKSRV TISVDTSKNQFSLKLSSVTAADTAVYYCARLGPDDYTLDGMDVWGQGTTVTVSSGSASAPTLFPLVSCDTSSVAVGCLAQ DFLPDSITFSWKYKNNSDISSTRGFPSVLRGGKYAATSQVLLPSKDVMQGTDEHVVCKVQHPNGNKEKNVP ; H,I ? 3 'polypeptide(L)' no no ;MAGFPLLLTLLTHCAGSWAQSVLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQLPGTAPKLLIYRNNQRPSGVPD RFSGSKSGTSASLAISGLRSEDEADYYCATWDDSLSAVIFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLIS DFFPGAVTVAWKADGAPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC ; ;MAGFPLLLTLLTHCAGSWAQSVLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQLPGTAPKLLIYRNNQRPSGVPD RFSGSKSGTSASLAISGLRSEDEADYYCATWDDSLSAVIFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLIS DFFPGAVTVAWKADGAPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC ; L,M ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 PRO n 1 3 LYS n 1 4 SER n 1 5 CYS n 1 6 ASP n 1 7 LYS n 1 8 THR n 1 9 HIS n 1 10 THR n 1 11 CYS n 1 12 PRO n 1 13 PRO n 1 14 CYS n 1 15 PRO n 1 16 ALA n 1 17 PRO n 1 18 GLU n 1 19 LEU n 1 20 LEU n 1 21 GLY n 1 22 GLY n 1 23 PRO n 1 24 SER n 1 25 VAL n 1 26 PHE n 1 27 LEU n 1 28 PHE n 1 29 PRO n 1 30 PRO n 1 31 LYS n 1 32 PRO n 1 33 LYS n 1 34 ASP n 1 35 THR n 1 36 LEU n 1 37 MET n 1 38 ILE n 1 39 SER n 1 40 ARG n 1 41 THR n 1 42 PRO n 1 43 GLU n 1 44 VAL n 1 45 THR n 1 46 CYS n 1 47 VAL n 1 48 VAL n 1 49 VAL n 1 50 ASP n 1 51 VAL n 1 52 SER n 1 53 HIS n 1 54 GLU n 1 55 GLU n 1 56 PRO n 1 57 GLU n 1 58 VAL n 1 59 LYS n 1 60 PHE n 1 61 ASN n 1 62 TRP n 1 63 TYR n 1 64 VAL n 1 65 ASP n 1 66 GLY n 1 67 VAL n 1 68 GLU n 1 69 VAL n 1 70 HIS n 1 71 ASN n 1 72 ALA n 1 73 LYS n 1 74 THR n 1 75 LYS n 1 76 PRO n 1 77 ARG n 1 78 GLU n 1 79 GLU n 1 80 GLN n 1 81 TYR n 1 82 ASN n 1 83 SER n 1 84 THR n 1 85 TYR n 1 86 ARG n 1 87 VAL n 1 88 VAL n 1 89 SER n 1 90 VAL n 1 91 LEU n 1 92 THR n 1 93 VAL n 1 94 LEU n 1 95 HIS n 1 96 GLN n 1 97 ASP n 1 98 TRP n 1 99 LEU n 1 100 ASN n 1 101 GLY n 1 102 LYS n 1 103 GLU n 1 104 TYR n 1 105 LYS n 1 106 CYS n 1 107 LYS n 1 108 VAL n 1 109 SER n 1 110 ASN n 1 111 LYS n 1 112 ALA n 1 113 LEU n 1 114 PRO n 1 115 ALA n 1 116 PRO n 1 117 ILE n 1 118 GLU n 1 119 LYS n 1 120 THR n 1 121 ILE n 1 122 SER n 1 123 LYS n 1 124 ALA n 1 125 LYS n 1 126 GLY n 1 127 GLN n 1 128 PRO n 1 129 ARG n 1 130 GLU n 1 131 PRO n 1 132 GLN n 1 133 VAL n 1 134 TYR n 1 135 THR n 1 136 LEU n 1 137 PRO n 1 138 PRO n 1 139 SER n 1 140 ARG n 1 141 ASP n 1 142 GLU n 1 143 LEU n 1 144 THR n 1 145 LYS n 1 146 ASN n 1 147 GLN n 1 148 VAL n 1 149 SER n 1 150 LEU n 1 151 THR n 1 152 CYS n 1 153 LEU n 1 154 VAL n 1 155 LYS n 1 156 GLY n 1 157 PHE n 1 158 TYR n 1 159 PRO n 1 160 SER n 1 161 ASP n 1 162 ILE n 1 163 ALA n 1 164 VAL n 1 165 GLU n 1 166 TRP n 1 167 GLU n 1 168 SER n 1 169 ASN n 1 170 GLY n 1 171 GLN n 1 172 PRO n 1 173 GLU n 1 174 ASN n 1 175 ASN n 1 176 TYR n 1 177 LYS n 1 178 THR n 1 179 THR n 1 180 PRO n 1 181 PRO n 1 182 VAL n 1 183 LEU n 1 184 ASP n 1 185 SER n 1 186 ASP n 1 187 GLY n 1 188 SER n 1 189 PHE n 1 190 PHE n 1 191 LEU n 1 192 TYR n 1 193 SER n 1 194 LYS n 1 195 LEU n 1 196 THR n 1 197 VAL n 1 198 ASP n 1 199 LYS n 1 200 SER n 1 201 ARG n 1 202 TRP n 1 203 GLN n 1 204 GLN n 1 205 GLY n 1 206 ASN n 1 207 VAL n 1 208 PHE n 1 209 SER n 1 210 CYS n 1 211 SER n 1 212 VAL n 1 213 MET n 1 214 HIS n 1 215 GLU n 1 216 ALA n 1 217 LEU n 1 218 HIS n 1 219 ASN n 1 220 HIS n 1 221 TYR n 1 222 THR n 1 223 GLN n 1 224 LYS n 1 225 SER n 1 226 LEU n 1 227 SER n 1 228 LEU n 1 229 SER n 1 230 PRO n 1 231 GLY n 1 232 LYS n 2 1 LEU n 2 2 LEU n 2 3 LEU n 2 4 VAL n 2 5 ALA n 2 6 ALA n 2 7 PRO n 2 8 ARG n 2 9 TRP n 2 10 LEU n 2 11 SER n 2 12 GLN n 2 13 LEU n 2 14 GLN n 2 15 LEU n 2 16 GLN n 2 17 GLU n 2 18 SER n 2 19 GLY n 2 20 PRO n 2 21 GLY n 2 22 LEU n 2 23 VAL n 2 24 LYS n 2 25 PRO n 2 26 SER n 2 27 GLU n 2 28 THR n 2 29 LEU n 2 30 SER n 2 31 LEU n 2 32 THR n 2 33 CYS n 2 34 THR n 2 35 VAL n 2 36 SER n 2 37 GLY n 2 38 GLY n 2 39 SER n 2 40 ILE n 2 41 SER n 2 42 ARG n 2 43 GLY n 2 44 SER n 2 45 HIS n 2 46 TYR n 2 47 TRP n 2 48 GLY n 2 49 TRP n 2 50 ILE n 2 51 ARG n 2 52 GLN n 2 53 PRO n 2 54 PRO n 2 55 GLY n 2 56 LYS n 2 57 GLY n 2 58 LEU n 2 59 GLU n 2 60 TRP n 2 61 ILE n 2 62 GLY n 2 63 SER n 2 64 ILE n 2 65 TYR n 2 66 TYR n 2 67 SER n 2 68 GLY n 2 69 ASN n 2 70 THR n 2 71 TYR n 2 72 PHE n 2 73 ASN n 2 74 PRO n 2 75 SER n 2 76 LEU n 2 77 LYS n 2 78 SER n 2 79 ARG n 2 80 VAL n 2 81 THR n 2 82 ILE n 2 83 SER n 2 84 VAL n 2 85 ASP n 2 86 THR n 2 87 SER n 2 88 LYS n 2 89 ASN n 2 90 GLN n 2 91 PHE n 2 92 SER n 2 93 LEU n 2 94 LYS n 2 95 LEU n 2 96 SER n 2 97 SER n 2 98 VAL n 2 99 THR n 2 100 ALA n 2 101 ALA n 2 102 ASP n 2 103 THR n 2 104 ALA n 2 105 VAL n 2 106 TYR n 2 107 TYR n 2 108 CYS n 2 109 ALA n 2 110 ARG n 2 111 LEU n 2 112 GLY n 2 113 PRO n 2 114 ASP n 2 115 ASP n 2 116 TYR n 2 117 THR n 2 118 LEU n 2 119 ASP n 2 120 GLY n 2 121 MET n 2 122 ASP n 2 123 VAL n 2 124 TRP n 2 125 GLY n 2 126 GLN n 2 127 GLY n 2 128 THR n 2 129 THR n 2 130 VAL n 2 131 THR n 2 132 VAL n 2 133 SER n 2 134 SER n 2 135 GLY n 2 136 SER n 2 137 ALA n 2 138 SER n 2 139 ALA n 2 140 PRO n 2 141 THR n 2 142 LEU n 2 143 PHE n 2 144 PRO n 2 145 LEU n 2 146 VAL n 2 147 SER n 2 148 CYS n 2 149 ASP n 2 150 THR n 2 151 SER n 2 152 SER n 2 153 VAL n 2 154 ALA n 2 155 VAL n 2 156 GLY n 2 157 CYS n 2 158 LEU n 2 159 ALA n 2 160 GLN n 2 161 ASP n 2 162 PHE n 2 163 LEU n 2 164 PRO n 2 165 ASP n 2 166 SER n 2 167 ILE n 2 168 THR n 2 169 PHE n 2 170 SER n 2 171 TRP n 2 172 LYS n 2 173 TYR n 2 174 LYS n 2 175 ASN n 2 176 ASN n 2 177 SER n 2 178 ASP n 2 179 ILE n 2 180 SER n 2 181 SER n 2 182 THR n 2 183 ARG n 2 184 GLY n 2 185 PHE n 2 186 PRO n 2 187 SER n 2 188 VAL n 2 189 LEU n 2 190 ARG n 2 191 GLY n 2 192 GLY n 2 193 LYS n 2 194 TYR n 2 195 ALA n 2 196 ALA n 2 197 THR n 2 198 SER n 2 199 GLN n 2 200 VAL n 2 201 LEU n 2 202 LEU n 2 203 PRO n 2 204 SER n 2 205 LYS n 2 206 ASP n 2 207 VAL n 2 208 MET n 2 209 GLN n 2 210 GLY n 2 211 THR n 2 212 ASP n 2 213 GLU n 2 214 HIS n 2 215 VAL n 2 216 VAL n 2 217 CYS n 2 218 LYS n 2 219 VAL n 2 220 GLN n 2 221 HIS n 2 222 PRO n 2 223 ASN n 2 224 GLY n 2 225 ASN n 2 226 LYS n 2 227 GLU n 2 228 LYS n 2 229 ASN n 2 230 VAL n 2 231 PRO n 3 1 MET n 3 2 ALA n 3 3 GLY n 3 4 PHE n 3 5 PRO n 3 6 LEU n 3 7 LEU n 3 8 LEU n 3 9 THR n 3 10 LEU n 3 11 LEU n 3 12 THR n 3 13 HIS n 3 14 CYS n 3 15 ALA n 3 16 GLY n 3 17 SER n 3 18 TRP n 3 19 ALA n 3 20 GLN n 3 21 SER n 3 22 VAL n 3 23 LEU n 3 24 THR n 3 25 GLN n 3 26 PRO n 3 27 PRO n 3 28 SER n 3 29 ALA n 3 30 SER n 3 31 GLY n 3 32 THR n 3 33 PRO n 3 34 GLY n 3 35 GLN n 3 36 ARG n 3 37 VAL n 3 38 THR n 3 39 ILE n 3 40 SER n 3 41 CYS n 3 42 SER n 3 43 GLY n 3 44 SER n 3 45 SER n 3 46 SER n 3 47 ASN n 3 48 ILE n 3 49 GLY n 3 50 SER n 3 51 ASN n 3 52 TYR n 3 53 VAL n 3 54 TYR n 3 55 TRP n 3 56 TYR n 3 57 GLN n 3 58 GLN n 3 59 LEU n 3 60 PRO n 3 61 GLY n 3 62 THR n 3 63 ALA n 3 64 PRO n 3 65 LYS n 3 66 LEU n 3 67 LEU n 3 68 ILE n 3 69 TYR n 3 70 ARG n 3 71 ASN n 3 72 ASN n 3 73 GLN n 3 74 ARG n 3 75 PRO n 3 76 SER n 3 77 GLY n 3 78 VAL n 3 79 PRO n 3 80 ASP n 3 81 ARG n 3 82 PHE n 3 83 SER n 3 84 GLY n 3 85 SER n 3 86 LYS n 3 87 SER n 3 88 GLY n 3 89 THR n 3 90 SER n 3 91 ALA n 3 92 SER n 3 93 LEU n 3 94 ALA n 3 95 ILE n 3 96 SER n 3 97 GLY n 3 98 LEU n 3 99 ARG n 3 100 SER n 3 101 GLU n 3 102 ASP n 3 103 GLU n 3 104 ALA n 3 105 ASP n 3 106 TYR n 3 107 TYR n 3 108 CYS n 3 109 ALA n 3 110 THR n 3 111 TRP n 3 112 ASP n 3 113 ASP n 3 114 SER n 3 115 LEU n 3 116 SER n 3 117 ALA n 3 118 VAL n 3 119 ILE n 3 120 PHE n 3 121 GLY n 3 122 GLY n 3 123 GLY n 3 124 THR n 3 125 LYS n 3 126 LEU n 3 127 THR n 3 128 VAL n 3 129 LEU n 3 130 GLY n 3 131 GLN n 3 132 PRO n 3 133 LYS n 3 134 ALA n 3 135 ALA n 3 136 PRO n 3 137 SER n 3 138 VAL n 3 139 THR n 3 140 LEU n 3 141 PHE n 3 142 PRO n 3 143 PRO n 3 144 SER n 3 145 SER n 3 146 GLU n 3 147 GLU n 3 148 LEU n 3 149 GLN n 3 150 ALA n 3 151 ASN n 3 152 LYS n 3 153 ALA n 3 154 THR n 3 155 LEU n 3 156 VAL n 3 157 CYS n 3 158 LEU n 3 159 ILE n 3 160 SER n 3 161 ASP n 3 162 PHE n 3 163 PHE n 3 164 PRO n 3 165 GLY n 3 166 ALA n 3 167 VAL n 3 168 THR n 3 169 VAL n 3 170 ALA n 3 171 TRP n 3 172 LYS n 3 173 ALA n 3 174 ASP n 3 175 GLY n 3 176 ALA n 3 177 PRO n 3 178 VAL n 3 179 LYS n 3 180 ALA n 3 181 GLY n 3 182 VAL n 3 183 GLU n 3 184 THR n 3 185 THR n 3 186 LYS n 3 187 PRO n 3 188 SER n 3 189 LYS n 3 190 GLN n 3 191 SER n 3 192 ASN n 3 193 ASN n 3 194 LYS n 3 195 TYR n 3 196 ALA n 3 197 ALA n 3 198 SER n 3 199 SER n 3 200 TYR n 3 201 LEU n 3 202 SER n 3 203 LEU n 3 204 THR n 3 205 PRO n 3 206 GLU n 3 207 GLN n 3 208 TRP n 3 209 LYS n 3 210 SER n 3 211 HIS n 3 212 ARG n 3 213 SER n 3 214 TYR n 3 215 SER n 3 216 CYS n 3 217 GLN n 3 218 VAL n 3 219 THR n 3 220 HIS n 3 221 GLU n 3 222 GLY n 3 223 SER n 3 224 THR n 3 225 VAL n 3 226 GLU n 3 227 LYS n 3 228 THR n 3 229 VAL n 3 230 ALA n 3 231 PRO n 3 232 THR n 3 233 GLU n 3 234 CYS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? HUMAN ? ? ? ? ? ? ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? ? ? ? 'CRICETULUS GRISEUS' 10029 ? ? ? ? ? ? ? ? 'CHINESE HAMSTER OVARY' ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? HUMAN ? ? ? ? ? ? ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? B-LYMPHOCYTE ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'CD5POSITIVE B CELLS' 3 1 sample ? ? ? HUMAN ? ? ? ? ? ? ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? B-LYMPHOCYTE ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'CD5POSITIVE B CELLS' # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform 1 UNP IGHG1_HUMAN 1 ? ? P01857 ? 2 PDB 2J6E 2 ? ? 2J6E ? 3 PDB 2J6E 3 ? ? 2J6E ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2J6E A 1 ? 232 ? P01857 99 ? 330 ? 216 447 2 1 2J6E B 1 ? 232 ? P01857 99 ? 330 ? 216 447 3 2 2J6E H 1 ? 231 ? 2J6E -10 ? 214 ? -10 214 4 2 2J6E I 1 ? 231 ? 2J6E -10 ? 214 ? -10 214 5 3 2J6E L 1 ? 234 ? 2J6E -18 ? 211 ? -18 211 6 3 2J6E M 1 ? 234 ? 2J6E -18 ? 211 ? -18 211 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2J6E GLU A 55 ? UNP P01857 ASP 153 conflict 270 1 2 2J6E GLU B 55 ? UNP P01857 ASP 153 conflict 270 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ACT non-polymer . 'ACETATE ION' ? 'C2 H3 O2 -1' 59.044 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CAC non-polymer . 'CACODYLATE ION' dimethylarsinate 'C2 H6 As O2 -1' 136.989 CD non-polymer . 'CADMIUM ION' ? 'Cd 2' 112.411 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUL L-saccharide . BETA-L-FUCOSE 6-DEOXY-BETA-L-GALACTOSE 'C6 H12 O5' 164.156 GAL D-saccharide . BETA-D-GALACTOSE ? 'C6 H12 O6' 180.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NDG D-saccharide . '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2J6E _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.28 _exptl_crystal.density_percent_sol 52.1 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.50 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '10% MPEG 5000, 3 MM ZINCACETATE, 3 MM CDCL2, 100 MM SODIUMCACODYLATE PH 6.5' # _diffrn.id 1 _diffrn.ambient_temp 100.0 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC CCD' _diffrn_detector.pdbx_collection_date ? _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.934 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID14-1' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID14-1 _diffrn_source.pdbx_wavelength 0.934 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 2J6E _reflns.observed_criterion_sigma_I 0.000 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 25.000 _reflns.d_resolution_high 3.000 _reflns.number_obs 36545 _reflns.number_all ? _reflns.percent_possible_obs 97.9 _reflns.pdbx_Rmerge_I_obs 0.08000 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 14.1000 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.600 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 3.00 _reflns_shell.d_res_low 3.11 _reflns_shell.percent_possible_all 93.8 _reflns_shell.Rmerge_I_obs 0.42000 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 3.200 _reflns_shell.pdbx_redundancy ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 2J6E _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 35995 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 2 _refine.pdbx_data_cutoff_high_absF 10000 _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 25.00 _refine.ls_d_res_high 3.00 _refine.ls_percent_reflns_obs 95.3 _refine.ls_R_factor_obs 0.2234 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2234 _refine.ls_R_factor_R_free 0.2877 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 6.8 _refine.ls_number_reflns_R_free 2563 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] -37.928 _refine.aniso_B[2][2] 15.850 _refine.aniso_B[3][3] 22.078 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 6.472 _refine.aniso_B[2][3] 0.000 _refine.solvent_model_details ? _refine.solvent_model_param_ksol 0.249712 _refine.solvent_model_param_bsol 26.6436 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 'PDB ENTRIES 1DN2, 2FB4' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.entry_id 2J6E _refine_analyze.Luzzati_coordinate_error_obs 0.434 _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs 25.0 _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 9819 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 292 _refine_hist.number_atoms_solvent 84 _refine_hist.number_atoms_total 10195 _refine_hist.d_res_high 3.00 _refine_hist.d_res_low 25.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.007422 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.36901 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 25.6 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 0.95 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? c_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? c_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? # loop_ _pdbx_xplor_file.pdbx_refine_id _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file 'X-RAY DIFFRACTION' 1 PROTEIN_REP.PARAM ? 'X-RAY DIFFRACTION' 2 CARBOHYDRATE.PARAM ? 'X-RAY DIFFRACTION' 3 ION.PARAM ? 'X-RAY DIFFRACTION' 4 WATER.PARAM ? 'X-RAY DIFFRACTION' 5 CACO.PAR ? # _struct.entry_id 2J6E _struct.title ;Crystal Structure of an Autoimmune Complex between a Human IgM Rheumatoid Factor and IgG1 Fc reveals a Novel Fc Epitope and Evidence for Affinity Maturation ; _struct.pdbx_descriptor 'IG GAMMA-1 CHAIN C REGION, IGM' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2J6E _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' _struct_keywords.text ;AUTOIMMUNE COMPLEX HUMAN IGM RHEUMATOID FACTOR IGG1-FC, IMMUNOGLOBULIN C REGION, MEMBRANE, GLYCOPROTEIN, TRANSMEMBRANE, HYPOTHETICAL PROTEIN, IMMUNE SYSTEM, IMMUNOGLOBULIN DOMAIN ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 3 ? G N N 4 ? H N N 5 ? I N N 6 ? J N N 7 ? K N N 7 ? L N N 7 ? M N N 8 ? N N N 8 ? O N N 9 ? P N N 10 ? Q N N 9 ? R N N 11 ? S N N 12 ? T N N 13 ? U N N 14 ? V N N 11 ? W N N 9 ? X N N 5 ? Y N N 7 ? Z N N 7 ? AA N N 8 ? BA N N 9 ? CA N N 10 ? DA N N 9 ? EA N N 11 ? FA N N 12 ? GA N N 9 ? HA N N 14 ? IA N N 11 ? JA N N 9 ? KA N N 8 ? LA N N 7 ? MA N N 15 ? NA N N 15 ? OA N N 15 ? PA N N 15 ? QA N N 15 ? RA N N 15 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LYS A 31 ? MET A 37 ? LYS A 246 MET A 252 1 ? 7 HELX_P HELX_P2 2 LEU A 94 ? ASN A 100 ? LEU A 309 ASN A 315 1 ? 7 HELX_P HELX_P3 3 SER A 139 ? LEU A 143 ? SER A 354 LEU A 358 5 ? 5 HELX_P HELX_P4 4 LYS A 199 ? GLY A 205 ? LYS A 414 GLY A 420 1 ? 7 HELX_P HELX_P5 5 LEU A 217 ? ASN A 219 ? LEU A 432 ASN A 434 5 ? 3 HELX_P HELX_P6 6 LYS B 31 ? MET B 37 ? LYS B 246 MET B 252 1 ? 7 HELX_P HELX_P7 7 LEU B 94 ? ASN B 100 ? LEU B 309 ASN B 315 1 ? 7 HELX_P HELX_P8 8 SER B 139 ? LYS B 145 ? SER B 354 LYS B 360 5 ? 7 HELX_P HELX_P9 9 LYS B 199 ? GLN B 204 ? LYS B 414 GLN B 419 1 ? 6 HELX_P HELX_P10 10 LEU B 217 ? TYR B 221 ? LEU B 432 TYR B 436 5 ? 5 HELX_P HELX_P11 11 SER C 39 ? GLY C 43 ? SER H 28 GLY H 32 5 ? 5 HELX_P HELX_P12 12 LEU C 76 ? SER C 78 ? LEU H 63 SER H 65 5 ? 3 HELX_P HELX_P13 13 SER D 39 ? GLY D 43 ? SER I 28 GLY I 32 5 ? 5 HELX_P HELX_P14 14 PRO D 74 ? LYS D 77 ? PRO I 61 LYS I 64 5 ? 4 HELX_P HELX_P15 15 THR D 86 ? LYS D 88 ? THR I 73 LYS I 75 5 ? 3 HELX_P HELX_P16 16 THR D 99 ? THR D 103 ? THR I 83 THR I 87 5 ? 5 HELX_P HELX_P17 17 SER E 144 ? GLN E 149 ? SER L 121 GLN L 126 1 ? 6 HELX_P HELX_P18 18 THR E 204 ? TRP E 208 ? THR L 181 TRP L 185 5 ? 5 HELX_P HELX_P19 19 GLY A 21 ? SER F 50 ? GLY A 236 SER M 30 5 ? 31 HELX_P HELX_P20 20 THR F 204 ? LYS F 209 ? THR M 181 LYS M 186 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 46 SG ? ? ? 1_555 A CYS 106 SG ? ? A CYS 261 A CYS 321 1_555 ? ? ? ? ? ? ? 2.036 ? disulf2 disulf ? ? A CYS 152 SG ? ? ? 1_555 A CYS 210 SG ? ? A CYS 367 A CYS 425 1_555 ? ? ? ? ? ? ? 2.035 ? disulf3 disulf ? ? B CYS 46 SG ? ? ? 1_555 B CYS 106 SG ? ? B CYS 261 B CYS 321 1_555 ? ? ? ? ? ? ? 2.034 ? disulf4 disulf ? ? B CYS 152 SG ? ? ? 1_555 B CYS 210 SG ? ? B CYS 367 B CYS 425 1_555 ? ? ? ? ? ? ? 2.031 ? disulf5 disulf ? ? C CYS 33 SG ? ? ? 1_555 C CYS 108 SG ? ? H CYS 22 H CYS 92 1_555 ? ? ? ? ? ? ? 2.042 ? disulf6 disulf ? ? C CYS 157 SG ? ? ? 1_555 C CYS 217 SG ? ? H CYS 140 H CYS 200 1_555 ? ? ? ? ? ? ? 2.031 ? disulf7 disulf ? ? D CYS 33 SG ? ? ? 1_555 D CYS 108 SG ? ? I CYS 22 I CYS 92 1_555 ? ? ? ? ? ? ? 2.045 ? disulf8 disulf ? ? D CYS 157 SG ? ? ? 1_555 D CYS 217 SG ? ? I CYS 140 I CYS 200 1_555 ? ? ? ? ? ? ? 2.028 ? disulf9 disulf ? ? E CYS 41 SG ? ? ? 1_555 E CYS 108 SG ? ? L CYS 22 L CYS 88 1_555 ? ? ? ? ? ? ? 2.027 ? disulf10 disulf ? ? E CYS 157 SG ? ? ? 1_555 E CYS 216 SG ? ? L CYS 134 L CYS 193 1_555 ? ? ? ? ? ? ? 2.035 ? disulf11 disulf ? ? F CYS 41 SG ? ? ? 1_555 F CYS 108 SG ? ? M CYS 22 M CYS 88 1_555 ? ? ? ? ? ? ? 2.036 ? disulf12 disulf ? ? F CYS 157 SG ? ? ? 1_555 F CYS 216 SG ? ? M CYS 134 M CYS 193 1_555 ? ? ? ? ? ? ? 2.032 ? covale1 covale ? ? A ASN 82 ND2 ? ? ? 1_555 O NAG . C1 ? ? A ASN 297 A NAG 1453 1_555 ? ? ? ? ? ? ? 1.451 ? metalc1 metalc ? ? G CD . CD ? ? ? 1_555 A GLU 79 OE1 ? ? A CD 1445 A GLU 294 4_546 ? ? ? ? ? ? ? 2.821 ? metalc2 metalc ? ? G CD . CD ? ? ? 1_555 A GLU 79 OE2 ? ? A CD 1445 A GLU 294 4_546 ? ? ? ? ? ? ? 2.009 ? metalc3 metalc ? ? G CD . CD ? ? ? 1_555 A HIS 220 NE2 ? ? A CD 1445 A HIS 435 1_555 ? ? ? ? ? ? ? 2.285 ? metalc4 metalc ? ? G CD . CD ? ? ? 1_555 A HIS 95 NE2 ? ? A CD 1445 A HIS 310 1_555 ? ? ? ? ? ? ? 2.039 ? metalc5 metalc ? ? G CD . CD ? ? ? 1_555 A HIS 53 NE2 ? ? A CD 1445 A HIS 268 4_546 ? ? ? ? ? ? ? 2.227 ? metalc6 metalc ? ? H ZN . ZN ? ? ? 1_555 I CAC . O1 ? ? A ZN 1446 A CAC 1447 1_555 ? ? ? ? ? ? ? 2.682 ? metalc7 metalc ? ? H ZN . ZN ? ? ? 1_555 A GLU 130 OE1 ? ? A ZN 1446 A GLU 345 1_555 ? ? ? ? ? ? ? 2.581 ? metalc8 metalc ? ? H ZN . ZN ? ? ? 1_555 A GLU 57 OE1 ? ? A ZN 1446 A GLU 272 4_546 ? ? ? ? ? ? ? 2.070 ? metalc9 metalc ? ? H ZN . ZN ? ? ? 1_555 A HIS 218 NE2 ? ? A ZN 1446 A HIS 433 1_555 ? ? ? ? ? ? ? 2.072 ? metalc10 metalc ? ? H ZN . ZN ? ? ? 1_555 A GLU 130 OE2 ? ? A ZN 1446 A GLU 345 1_555 ? ? ? ? ? ? ? 1.942 ? metalc11 metalc ? ? H ZN . ZN ? ? ? 1_555 A GLU 57 OE2 ? ? A ZN 1446 A GLU 272 4_546 ? ? ? ? ? ? ? 1.933 ? covale2 covale ? ? O NAG . O6 ? ? ? 1_555 P FUL . C1 ? ? A NAG 1453 A FUL 1454 1_555 ? ? ? ? ? ? ? 1.388 ? covale3 covale ? ? O NAG . O4 ? ? ? 1_555 Q NAG . C1 ? ? A NAG 1453 A NAG 1455 1_555 ? ? ? ? ? ? ? 1.378 ? covale4 covale ? ? Q NAG . O4 ? ? ? 1_555 R BMA . C1 ? ? A NAG 1455 A BMA 1456 1_555 ? ? ? ? ? ? ? 1.387 ? covale5 covale ? ? R BMA . O6 ? ? ? 1_555 S MAN . C1 ? ? A BMA 1456 A MAN 1457 1_555 ? ? ? ? ? ? ? 1.385 ? covale6 covale ? ? R BMA . O3 ? ? ? 1_555 V BMA . C1 ? ? A BMA 1456 A BMA 1460 1_555 ? ? ? ? ? ? ? 1.397 ? covale7 covale ? ? S MAN . O2 ? ? ? 1_555 T NDG . C1 ? ? A MAN 1457 A NDG 1458 1_555 ? ? ? ? ? ? ? 1.386 ? covale8 covale ? ? T NDG . O4 ? ? ? 1_555 U GAL . C1 ? ? A NDG 1458 A GAL 1459 1_555 ? ? ? ? ? ? ? 1.387 ? covale9 covale ? ? V BMA . O2 ? ? ? 1_555 W NAG . C1 ? ? A BMA 1460 A NAG 1461 1_555 ? ? ? ? ? ? ? 1.394 ? covale10 covale ? ? B ASN 82 ND2 ? ? ? 1_555 BA NAG . C1 ? ? B ASN 297 B NAG 1450 1_555 ? ? ? ? ? ? ? 1.455 ? metalc12 metalc ? ? X ZN . ZN ? ? ? 1_555 F HIS 211 NE2 ? ? B ZN 1446 M HIS 188 4_545 ? ? ? ? ? ? ? 2.101 ? covale11 covale ? ? BA NAG . O4 ? ? ? 1_555 DA NAG . C1 ? ? B NAG 1450 B NAG 1452 1_555 ? ? ? ? ? ? ? 1.394 ? covale12 covale ? ? BA NAG . O6 ? ? ? 1_555 CA FUL . C1 ? ? B NAG 1450 B FUL 1451 1_555 ? ? ? ? ? ? ? 1.407 ? covale13 covale ? ? DA NAG . O4 ? ? ? 1_555 EA BMA . C1 ? ? B NAG 1452 B BMA 1453 1_555 ? ? ? ? ? ? ? 1.388 ? covale14 covale ? ? EA BMA . O6 ? ? ? 1_555 FA MAN . C1 ? ? B BMA 1453 B MAN 1454 1_555 ? ? ? ? ? ? ? 1.402 ? covale15 covale ? ? EA BMA . O3 ? ? ? 1_555 IA BMA . C1 ? ? B BMA 1453 B BMA 1457 1_555 ? ? ? ? ? ? ? 1.404 ? covale16 covale ? ? FA MAN . O2 ? ? ? 1_555 GA NAG . C1 ? ? B MAN 1454 B NAG 1455 1_555 ? ? ? ? ? ? ? 1.389 ? covale17 covale ? ? GA NAG . O4 ? ? ? 1_555 HA GAL . C1 ? ? B NAG 1455 B GAL 1456 1_555 ? ? ? ? ? ? ? 1.393 ? covale18 covale ? ? IA BMA . O2 ? ? ? 1_555 JA NAG . C1 ? ? B BMA 1457 B NAG 1458 1_555 ? ? ? ? ? ? ? 1.395 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TYR 158 A . ? TYR 373 A PRO 159 A ? PRO 374 A 1 0.15 2 TYR 158 B . ? TYR 373 B PRO 159 B ? PRO 374 B 1 -0.03 3 PHE 163 E . ? PHE 140 L PRO 164 E ? PRO 141 L 1 0.16 4 PHE 163 F . ? PHE 140 M PRO 164 F ? PRO 141 M 1 -0.30 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 4 ? AB ? 4 ? AC ? 4 ? AD ? 4 ? AE ? 3 ? BA ? 4 ? BB ? 3 ? BC ? 4 ? BD ? 4 ? BE ? 3 ? HA ? 4 ? HB ? 5 ? HC ? 5 ? HD ? 3 ? HE ? 3 ? HF ? 2 ? IA ? 4 ? IB ? 9 ? IC ? 7 ? ID ? 3 ? LA ? 3 ? LB ? 4 ? LC ? 4 ? LD ? 4 ? MA ? 3 ? MB ? 7 ? MC ? 3 ? MD ? 2 ? ME ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? anti-parallel AA 2 3 ? anti-parallel AA 3 4 ? anti-parallel AB 1 2 ? anti-parallel AB 2 3 ? anti-parallel AB 3 4 ? anti-parallel AC 1 2 ? anti-parallel AC 2 3 ? anti-parallel AC 3 4 ? anti-parallel AD 1 2 ? anti-parallel AD 2 3 ? anti-parallel AD 3 4 ? anti-parallel AE 1 2 ? anti-parallel AE 2 3 ? anti-parallel BA 1 2 ? anti-parallel BA 2 3 ? anti-parallel BA 3 4 ? anti-parallel BB 1 2 ? anti-parallel BB 2 3 ? anti-parallel BC 1 2 ? anti-parallel BC 2 3 ? anti-parallel BC 3 4 ? anti-parallel BD 1 2 ? anti-parallel BD 2 3 ? anti-parallel BD 3 4 ? anti-parallel BE 1 2 ? anti-parallel BE 2 3 ? anti-parallel HA 1 2 ? anti-parallel HA 2 3 ? anti-parallel HA 3 4 ? anti-parallel HB 1 2 ? anti-parallel HB 2 3 ? anti-parallel HB 3 4 ? anti-parallel HB 4 5 ? anti-parallel HC 1 2 ? anti-parallel HC 2 3 ? anti-parallel HC 3 4 ? anti-parallel HC 4 5 ? anti-parallel HD 1 2 ? anti-parallel HD 2 3 ? anti-parallel HE 1 2 ? anti-parallel HE 2 3 ? anti-parallel HF 1 2 ? anti-parallel IA 1 2 ? anti-parallel IA 2 3 ? anti-parallel IA 3 4 ? anti-parallel IB 1 2 ? parallel IB 2 3 ? anti-parallel IB 4 5 ? anti-parallel IB 5 6 ? anti-parallel IB 6 7 ? anti-parallel IB 7 8 ? anti-parallel IB 8 9 ? anti-parallel IC 1 2 ? anti-parallel IC 2 3 ? anti-parallel IC 3 4 ? anti-parallel IC 4 5 ? anti-parallel IC 5 6 ? anti-parallel IC 6 7 ? anti-parallel ID 1 2 ? anti-parallel ID 2 3 ? anti-parallel LA 1 2 ? anti-parallel LA 2 3 ? anti-parallel LB 1 2 ? anti-parallel LB 2 3 ? anti-parallel LB 3 4 ? anti-parallel LC 1 2 ? anti-parallel LC 2 3 ? anti-parallel LC 3 4 ? anti-parallel LD 1 2 ? anti-parallel LD 2 3 ? anti-parallel LD 3 4 ? anti-parallel MA 1 2 ? anti-parallel MA 2 3 ? anti-parallel MB 1 2 ? anti-parallel MB 2 3 ? anti-parallel MB 3 4 ? anti-parallel MB 4 5 ? anti-parallel MB 5 6 ? anti-parallel MB 6 7 ? anti-parallel MC 1 2 ? anti-parallel MC 2 3 ? anti-parallel MD 1 2 ? anti-parallel ME 1 2 ? anti-parallel ME 2 3 ? anti-parallel ME 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 SER A 24 ? PHE A 28 ? SER A 239 PHE A 243 AA 2 GLU A 43 ? VAL A 51 ? GLU A 258 VAL A 266 AA 3 TYR A 85 ? THR A 92 ? TYR A 300 THR A 307 AA 4 LYS A 73 ? GLU A 79 ? LYS A 288 GLU A 294 AB 1 VAL A 67 ? VAL A 69 ? VAL A 282 VAL A 284 AB 2 VAL A 58 ? VAL A 64 ? VAL A 273 VAL A 279 AB 3 TYR A 104 ? ASN A 110 ? TYR A 319 ASN A 325 AB 4 ILE A 117 ? ILE A 121 ? ILE A 332 ILE A 336 AC 1 GLN A 132 ? LEU A 136 ? GLN A 347 LEU A 351 AC 2 GLN A 147 ? PHE A 157 ? GLN A 362 PHE A 372 AC 3 PHE A 189 ? ASP A 198 ? PHE A 404 ASP A 413 AC 4 TYR A 176 ? THR A 178 ? TYR A 391 THR A 393 AD 1 GLN A 132 ? LEU A 136 ? GLN A 347 LEU A 351 AD 2 GLN A 147 ? PHE A 157 ? GLN A 362 PHE A 372 AD 3 PHE A 189 ? ASP A 198 ? PHE A 404 ASP A 413 AD 4 VAL A 182 ? LEU A 183 ? VAL A 397 LEU A 398 AE 1 ALA A 163 ? SER A 168 ? ALA A 378 SER A 383 AE 2 VAL A 207 ? MET A 213 ? VAL A 422 MET A 428 AE 3 TYR A 221 ? SER A 227 ? TYR A 436 SER A 442 BA 1 SER B 24 ? PHE B 28 ? SER B 239 PHE B 243 BA 2 GLU B 43 ? VAL B 49 ? GLU B 258 VAL B 264 BA 3 TYR B 85 ? THR B 92 ? TYR B 300 THR B 307 BA 4 GLU B 78 ? GLU B 79 ? GLU B 293 GLU B 294 BB 1 PHE B 60 ? VAL B 64 ? PHE B 275 VAL B 279 BB 2 TYR B 104 ? VAL B 108 ? TYR B 319 VAL B 323 BB 3 GLU B 118 ? ILE B 121 ? GLU B 333 ILE B 336 BC 1 GLN B 132 ? LEU B 136 ? GLN B 347 LEU B 351 BC 2 GLN B 147 ? PHE B 157 ? GLN B 362 PHE B 372 BC 3 PHE B 189 ? ASP B 198 ? PHE B 404 ASP B 413 BC 4 TYR B 176 ? THR B 178 ? TYR B 391 THR B 393 BD 1 GLN B 132 ? LEU B 136 ? GLN B 347 LEU B 351 BD 2 GLN B 147 ? PHE B 157 ? GLN B 362 PHE B 372 BD 3 PHE B 189 ? ASP B 198 ? PHE B 404 ASP B 413 BD 4 VAL B 182 ? LEU B 183 ? VAL B 397 LEU B 398 BE 1 ALA B 163 ? GLU B 167 ? ALA B 378 GLU B 382 BE 2 PHE B 208 ? MET B 213 ? PHE B 423 MET B 428 BE 3 THR B 222 ? LEU B 226 ? THR B 437 LEU B 441 HA 1 GLN C 14 ? SER C 18 ? GLN H 3 SER H 7 HA 2 THR C 28 ? SER C 36 ? THR H 17 SER H 25 HA 3 GLN C 90 ? SER C 96 A GLN H 77 SER H 82 HA 4 VAL C 80 ? ASP C 85 ? VAL H 67 ASP H 72 HB 1 THR C 70 ? PHE C 72 ? THR H 57 PHE H 59 HB 2 GLU C 59 ? ILE C 64 ? GLU H 46 ILE H 51 HB 3 TRP C 47 A GLN C 52 ? TRP H 35 GLN H 39 HB 4 ALA C 104 ? LEU C 111 ? ALA H 88 LEU H 95 HB 5 THR C 129 ? VAL C 130 ? THR H 108 VAL H 109 HC 1 THR C 70 ? PHE C 72 ? THR H 57 PHE H 59 HC 2 GLU C 59 ? ILE C 64 ? GLU H 46 ILE H 51 HC 3 TRP C 47 A GLN C 52 ? TRP H 35 GLN H 39 HC 4 ALA C 104 ? LEU C 111 ? ALA H 88 LEU H 95 HC 5 MET C 121 E TRP C 124 ? MET H 100 TRP H 103 HD 1 THR C 141 ? PRO C 144 ? THR H 120 PRO H 123 HD 2 VAL C 153 ? GLN C 160 ? VAL H 136 GLN H 143 HD 3 GLN C 199 ? LEU C 202 ? GLN H 182 LEU H 185 HE 1 TRP C 171 ? LYS C 172 ? TRP H 154 LYS H 155 HE 2 VAL C 215 ? LYS C 218 ? VAL H 198 LYS H 201 HE 3 GLU C 227 ? VAL C 230 ? GLU H 210 VAL H 213 HF 1 VAL C 188 ? LEU C 189 ? VAL H 171 LEU H 172 HF 2 TYR C 194 ? ALA C 195 ? TYR H 177 ALA H 178 IA 1 GLN D 14 ? SER D 18 ? GLN I 3 SER I 7 IA 2 LEU D 29 ? SER D 36 ? LEU I 18 SER I 25 IA 3 GLN D 90 ? LEU D 95 ? GLN I 77 LEU I 82 IA 4 ILE D 82 ? ASP D 85 ? ILE I 69 ASP I 72 IB 1 LEU D 22 ? VAL D 23 ? LEU I 11 VAL I 12 IB 2 THR D 128 ? VAL D 132 ? THR I 107 VAL I 111 IB 3 ALA D 104 ? LEU D 111 ? ALA I 88 LEU I 95 IB 4 THR D 70 ? PHE D 72 ? THR I 57 PHE I 59 IB 5 GLU D 59 ? ILE D 64 ? GLU I 46 ILE I 51 IB 6 TRP D 47 A GLN D 52 ? TRP I 35 GLN I 39 IB 7 ALA D 104 ? LEU D 111 ? ALA I 88 LEU I 95 IB 8 ASP D 122 ? TRP D 124 ? ASP I 101 TRP I 103 IB 9 ALA D 104 ? LEU D 111 ? ALA I 88 LEU I 95 IC 1 THR D 141 ? LEU D 145 ? THR I 120 LEU I 124 IC 2 VAL D 153 ? GLN D 160 ? VAL I 136 GLN I 143 IC 3 LYS D 193 ? LEU D 202 ? LYS I 176 LEU I 185 IC 4 ARG D 183 ? GLY D 184 ? ARG I 166 GLY I 167 IC 5 LYS D 193 ? LEU D 202 ? LYS I 176 LEU I 185 IC 6 VAL D 188 ? ARG D 190 ? VAL I 171 ARG I 173 IC 7 LYS D 193 ? LEU D 202 ? LYS I 176 LEU I 185 ID 1 PHE D 169 ? LYS D 172 ? PHE I 152 LYS I 155 ID 2 VAL D 215 ? VAL D 219 ? VAL I 198 VAL I 202 ID 3 LYS D 226 ? VAL D 230 ? LYS I 209 VAL I 213 LA 1 ARG E 36 ? SER E 42 ? ARG L 17 SER L 23 LA 2 SER E 90 ? SER E 96 ? SER L 70 SER L 76 LA 3 PHE E 82 ? SER E 87 ? PHE L 62 SER L 67 LB 1 LYS E 65 ? ILE E 68 ? LYS L 45 ILE L 48 LB 2 TYR E 54 ? GLN E 58 ? TYR L 34 GLN L 38 LB 3 ASP E 105 ? ASP E 112 ? ASP L 85 ASP L 92 LB 4 ALA E 117 B PHE E 120 ? ALA L 95 PHE L 98 LC 1 LEU E 140 ? PHE E 141 ? LEU L 117 PHE L 118 LC 2 LEU E 155 ? CYS E 157 ? LEU L 132 CYS L 134 LC 3 SER E 199 ? LEU E 201 ? SER L 176 LEU L 178 LC 4 VAL E 182 ? THR E 184 ? VAL L 159 THR L 161 LD 1 ALA E 176 ? PRO E 177 ? ALA L 153 PRO L 154 LD 2 THR E 168 ? ALA E 173 ? THR L 145 ALA L 150 LD 3 TYR E 214 ? THR E 219 ? TYR L 191 THR L 196 LD 4 LYS E 227 ? VAL E 229 ? LYS L 204 VAL L 206 MA 1 VAL F 37 ? SER F 42 ? VAL M 18 SER M 23 MA 2 SER F 90 ? ILE F 95 ? SER M 70 ILE M 75 MA 3 PHE F 82 ? SER F 85 ? PHE M 62 SER M 65 MB 1 LEU F 66 ? ILE F 68 ? LEU M 46 ILE M 48 MB 2 TYR F 54 ? GLN F 58 ? TYR M 34 GLN M 38 MB 3 ALA F 104 ? ASP F 112 ? ALA M 84 ASP M 92 MB 4 ALA F 117 B PHE F 120 ? ALA M 95 PHE M 98 MB 5 ALA F 104 ? ASP F 112 ? ALA M 84 ASP M 92 MB 6 THR F 124 ? LEU F 126 ? THR M 102 LEU M 104 MB 7 ALA F 104 ? ASP F 112 ? ALA M 84 ASP M 92 MC 1 LEU F 140 ? PHE F 141 ? LEU M 117 PHE M 118 MC 2 LEU F 155 ? CYS F 157 ? LEU M 132 CYS M 134 MC 3 SER F 199 ? LEU F 201 ? SER M 176 LEU M 178 MD 1 ASP F 161 ? PHE F 162 ? ASP M 138 PHE M 139 MD 2 TYR F 195 ? ALA F 196 ? TYR M 172 ALA M 173 ME 1 ALA F 176 ? PRO F 177 ? ALA M 153 PRO M 154 ME 2 VAL F 169 ? ALA F 173 ? VAL M 146 ALA M 150 ME 3 TYR F 214 ? VAL F 218 ? TYR M 191 VAL M 195 ME 4 GLU F 226 ? VAL F 229 ? GLU M 203 VAL M 206 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N PHE A 28 ? N PHE A 243 O THR A 45 ? O THR A 260 AA 2 3 N VAL A 51 ? N VAL A 266 O TYR A 85 ? O TYR A 300 AA 3 4 N VAL A 90 ? N VAL A 305 O LYS A 73 ? O LYS A 288 AB 1 2 N VAL A 69 ? N VAL A 284 O TRP A 62 ? O TRP A 277 AB 2 3 N TYR A 63 ? N TYR A 278 O LYS A 105 ? O LYS A 320 AB 3 4 N VAL A 108 ? N VAL A 323 O ILE A 117 ? O ILE A 332 AC 1 2 N LEU A 136 ? N LEU A 351 O THR A 151 ? O THR A 366 AC 2 3 N PHE A 157 ? N PHE A 372 O PHE A 189 ? O PHE A 404 AC 3 4 N LYS A 194 ? N LYS A 409 O LYS A 177 ? O LYS A 392 AD 1 2 N LEU A 136 ? N LEU A 351 O THR A 151 ? O THR A 366 AD 2 3 N PHE A 157 ? N PHE A 372 O PHE A 189 ? O PHE A 404 AD 3 4 N PHE A 190 ? N PHE A 405 O VAL A 182 ? O VAL A 397 AE 1 2 N GLU A 167 ? N GLU A 382 O SER A 209 ? O SER A 424 AE 2 3 N VAL A 212 ? N VAL A 427 O THR A 222 ? O THR A 437 BA 1 2 N PHE B 28 ? N PHE B 243 O THR B 45 ? O THR B 260 BA 2 3 N VAL B 48 ? N VAL B 263 O VAL B 87 ? O VAL B 302 BA 3 4 N ARG B 86 ? N ARG B 301 O GLU B 78 ? O GLU B 293 BB 1 2 N TYR B 63 ? N TYR B 278 O LYS B 105 ? O LYS B 320 BB 2 3 N CYS B 106 ? N CYS B 321 O LYS B 119 ? O LYS B 334 BC 1 2 N LEU B 136 ? N LEU B 351 O THR B 151 ? O THR B 366 BC 2 3 N PHE B 157 ? N PHE B 372 O PHE B 189 ? O PHE B 404 BC 3 4 N LYS B 194 ? N LYS B 409 O LYS B 177 ? O LYS B 392 BD 1 2 N LEU B 136 ? N LEU B 351 O THR B 151 ? O THR B 366 BD 2 3 N PHE B 157 ? N PHE B 372 O PHE B 189 ? O PHE B 404 BD 3 4 N PHE B 190 ? N PHE B 405 O VAL B 182 ? O VAL B 397 BE 1 2 N GLU B 167 ? N GLU B 382 O SER B 209 ? O SER B 424 BE 2 3 N VAL B 212 ? N VAL B 427 O THR B 222 ? O THR B 437 HA 1 2 N SER C 18 ? N SER H 7 O THR C 32 ? O THR H 21 HA 2 3 N CYS C 33 ? N CYS H 22 O PHE C 91 ? O PHE H 78 HA 3 4 N LYS C 94 ? N LYS H 81 O THR C 81 ? O THR H 68 HB 1 2 N TYR C 71 ? N TYR H 58 O SER C 63 ? O SER H 50 HB 2 3 N ILE C 64 ? N ILE H 51 O TRP C 47 A O TRP H 35 HB 3 4 N GLN C 52 ? N GLN H 39 O VAL C 105 ? O VAL H 89 HB 4 5 N ALA C 104 ? N ALA H 88 O VAL C 130 ? O VAL H 109 HC 1 2 N TYR C 71 ? N TYR H 58 O SER C 63 ? O SER H 50 HC 2 3 N ILE C 64 ? N ILE H 51 O TRP C 47 A O TRP H 35 HC 3 4 N GLN C 52 ? N GLN H 39 O VAL C 105 ? O VAL H 89 HC 4 5 O ARG C 110 ? O ARG H 94 N ASP C 122 ? N ASP H 101 HD 1 2 N PHE C 143 ? N PHE H 122 O LEU C 158 ? O LEU H 141 HD 2 3 N VAL C 155 ? N VAL H 138 O VAL C 200 ? O VAL H 183 HE 1 2 N LYS C 172 ? N LYS H 155 O VAL C 216 ? O VAL H 199 HE 2 3 N CYS C 217 ? N CYS H 200 O LYS C 228 ? O LYS H 211 HF 1 2 N VAL C 188 ? N VAL H 171 O ALA C 195 ? O ALA H 178 IA 1 2 N SER D 18 ? N SER I 7 O THR D 32 ? O THR I 21 IA 2 3 N CYS D 33 ? N CYS I 22 O PHE D 91 ? O PHE I 78 IA 3 4 N SER D 92 ? N SER I 79 O SER D 83 ? O SER I 70 IB 1 2 N VAL D 23 ? N VAL I 12 O THR D 131 ? O THR I 110 IB 2 3 N VAL D 130 ? N VAL I 109 O ALA D 104 ? O ALA I 88 IB 4 5 N TYR D 71 ? N TYR I 58 O SER D 63 ? O SER I 50 IB 5 6 N ILE D 64 ? N ILE I 51 O TRP D 47 A O TRP I 35 IB 6 7 N GLN D 52 ? N GLN I 39 O VAL D 105 ? O VAL I 89 IB 7 8 N ARG D 110 ? N ARG I 94 O VAL D 123 ? O VAL I 102 IB 8 9 N VAL D 123 ? N VAL I 102 O ARG D 110 ? O ARG I 94 IC 1 2 N LEU D 145 ? N LEU I 124 O GLY D 156 ? O GLY I 139 IC 2 3 N ALA D 159 ? N ALA I 142 O ALA D 196 ? O ALA I 179 IC 3 4 N GLN D 199 ? N GLN I 182 O ARG D 183 ? O ARG I 166 IC 4 5 N ARG D 183 ? N ARG I 166 O GLN D 199 ? O GLN I 182 IC 5 6 N ALA D 195 ? N ALA I 178 O VAL D 188 ? O VAL I 171 IC 6 7 N ARG D 190 ? N ARG I 173 O LYS D 193 ? O LYS I 176 ID 1 2 N LYS D 172 ? N LYS I 155 O VAL D 216 ? O VAL I 199 ID 2 3 N VAL D 219 ? N VAL I 202 O LYS D 226 ? O LYS I 209 LA 1 2 N CYS E 41 ? N CYS L 22 O ALA E 91 ? O ALA L 71 LA 2 3 N ALA E 94 ? N ALA L 74 O SER E 83 ? O SER L 63 LB 1 2 N LEU E 67 ? N LEU L 47 O TRP E 55 ? O TRP L 35 LB 2 3 N GLN E 58 ? N GLN L 38 O ASP E 105 ? O ASP L 85 LB 3 4 N ASP E 112 ? N ASP L 92 O ALA E 117 B O ALA L 95 LC 1 2 O PHE E 141 ? O PHE L 118 N VAL E 156 ? N VAL L 133 LC 2 3 N CYS E 157 ? N CYS L 134 O SER E 199 ? O SER L 176 LC 3 4 N TYR E 200 ? N TYR L 177 O GLU E 183 ? O GLU L 160 LD 1 2 O ALA E 176 ? O ALA L 153 N ALA E 173 ? N ALA L 150 LD 2 3 N LYS E 172 ? N LYS L 149 O SER E 215 ? O SER L 192 LD 3 4 N CYS E 216 ? N CYS L 193 O LYS E 227 ? O LYS L 204 MA 1 2 N CYS F 41 ? N CYS M 22 O ALA F 91 ? O ALA M 71 MA 2 3 N ALA F 94 ? N ALA M 74 O SER F 83 ? O SER M 63 MB 1 2 N LEU F 67 ? N LEU M 47 O TRP F 55 ? O TRP M 35 MB 2 3 N GLN F 58 ? N GLN M 38 O ASP F 105 ? O ASP M 85 MB 3 4 N ASP F 112 ? N ASP M 92 O ALA F 117 B O ALA M 95 MB 4 5 N ILE F 119 ? N ILE M 97 O THR F 110 ? O THR M 90 MB 5 6 N TYR F 106 ? N TYR M 86 O THR F 124 ? O THR M 102 MB 6 7 N LEU F 126 ? N LEU M 104 O ALA F 104 ? O ALA M 84 MC 1 2 N PHE F 141 ? N PHE M 118 O VAL F 156 ? O VAL M 133 MC 2 3 N CYS F 157 ? N CYS M 134 O SER F 199 ? O SER M 176 MD 1 2 N PHE F 162 ? N PHE M 139 O TYR F 195 ? O TYR M 172 ME 1 2 O ALA F 176 ? O ALA M 153 N ALA F 173 ? N ALA M 150 ME 2 3 N LYS F 172 ? N LYS M 149 O SER F 215 ? O SER M 192 ME 3 4 N CYS F 216 ? N CYS M 193 O LYS F 227 ? O LYS M 204 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A1453' AC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE FUL A1454' AC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A1455' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE BMA A1456' AC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MAN A1457' AC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NDG A1458' AC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GAL A1459' AC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE BMA A1460' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A1461' BC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B1450' BC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUL B1451' BC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG B1452' BC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE BMA B1453' BC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MAN B1454' BC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B1455' BC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GAL B1456' BC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE BMA B1457' BC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG B1458' CC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CD A1445' CC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN A1446' CC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CAC A1447' CC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE ACT A1451' CC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ACT A1452' CC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE ZN B1446' CC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ACT B1449' CC8 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE ACT H1215' CC9 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MPD A1448' DC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MPD A1449' DC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MPD A1450' DC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE MPD B1447' DC4 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MPD B1448' DC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MPD M1212' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 VAL A 49 ? VAL A 264 . ? 1_555 ? 2 AC1 6 ASP A 50 ? ASP A 265 . ? 1_555 ? 3 AC1 6 GLN A 80 ? GLN A 295 . ? 1_555 ? 4 AC1 6 ASN A 82 ? ASN A 297 . ? 1_555 ? 5 AC1 6 FUL P . ? FUL A 1454 . ? 1_555 ? 6 AC1 6 NAG Q . ? NAG A 1455 . ? 1_555 ? 7 AC2 4 TYR A 81 ? TYR A 296 . ? 1_555 ? 8 AC2 4 NAG O . ? NAG A 1453 . ? 1_555 ? 9 AC2 4 NAG Q . ? NAG A 1455 . ? 1_555 ? 10 AC2 4 HOH MA . ? HOH A 2031 . ? 1_555 ? 11 AC3 6 VAL A 49 ? VAL A 264 . ? 1_555 ? 12 AC3 6 ARG A 86 ? ARG A 301 . ? 1_555 ? 13 AC3 6 NAG O . ? NAG A 1453 . ? 1_555 ? 14 AC3 6 FUL P . ? FUL A 1454 . ? 1_555 ? 15 AC3 6 BMA R . ? BMA A 1456 . ? 1_555 ? 16 AC3 6 MAN S . ? MAN A 1457 . ? 1_555 ? 17 AC4 4 PHE A 28 ? PHE A 243 . ? 1_555 ? 18 AC4 4 NAG Q . ? NAG A 1455 . ? 1_555 ? 19 AC4 4 MAN S . ? MAN A 1457 . ? 1_555 ? 20 AC4 4 BMA V . ? BMA A 1460 . ? 1_555 ? 21 AC5 4 ARG A 86 ? ARG A 301 . ? 1_555 ? 22 AC5 4 NAG Q . ? NAG A 1455 . ? 1_555 ? 23 AC5 4 BMA R . ? BMA A 1456 . ? 1_555 ? 24 AC5 4 NDG T . ? NDG A 1458 . ? 1_555 ? 25 AC6 6 PHE A 28 ? PHE A 243 . ? 1_555 ? 26 AC6 6 LYS A 31 ? LYS A 246 . ? 1_555 ? 27 AC6 6 THR A 45 ? THR A 260 . ? 1_555 ? 28 AC6 6 MAN S . ? MAN A 1457 . ? 1_555 ? 29 AC6 6 GAL U . ? GAL A 1459 . ? 1_555 ? 30 AC6 6 HOH MA . ? HOH A 2032 . ? 1_555 ? 31 AC7 6 PRO A 29 ? PRO A 244 . ? 1_555 ? 32 AC7 6 PRO A 30 ? PRO A 245 . ? 1_555 ? 33 AC7 6 LYS A 31 ? LYS A 246 . ? 1_555 ? 34 AC7 6 GLU A 43 ? GLU A 258 . ? 1_555 ? 35 AC7 6 THR A 45 ? THR A 260 . ? 1_555 ? 36 AC7 6 NDG T . ? NDG A 1458 . ? 1_555 ? 37 AC8 3 BMA R . ? BMA A 1456 . ? 1_555 ? 38 AC8 3 NAG W . ? NAG A 1461 . ? 1_555 ? 39 AC8 3 NAG DA . ? NAG B 1452 . ? 1_555 ? 40 AC9 2 LYS A 119 ? LYS A 334 . ? 1_555 ? 41 AC9 2 BMA V . ? BMA A 1460 . ? 1_555 ? 42 BC1 6 VAL B 49 ? VAL B 264 . ? 1_555 ? 43 BC1 6 ASP B 50 ? ASP B 265 . ? 1_555 ? 44 BC1 6 GLN B 80 ? GLN B 295 . ? 1_555 ? 45 BC1 6 ASN B 82 ? ASN B 297 . ? 1_555 ? 46 BC1 6 FUL CA . ? FUL B 1451 . ? 1_555 ? 47 BC1 6 NAG DA . ? NAG B 1452 . ? 1_555 ? 48 BC2 3 NAG BA . ? NAG B 1450 . ? 1_555 ? 49 BC2 3 NAG DA . ? NAG B 1452 . ? 1_555 ? 50 BC2 3 MAN FA . ? MAN B 1454 . ? 1_555 ? 51 BC3 8 BMA V . ? BMA A 1460 . ? 1_555 ? 52 BC3 8 PHE B 26 ? PHE B 241 . ? 1_555 ? 53 BC3 8 VAL B 49 ? VAL B 264 . ? 1_555 ? 54 BC3 8 ARG B 86 ? ARG B 301 . ? 1_555 ? 55 BC3 8 NAG BA . ? NAG B 1450 . ? 1_555 ? 56 BC3 8 FUL CA . ? FUL B 1451 . ? 1_555 ? 57 BC3 8 BMA EA . ? BMA B 1453 . ? 1_555 ? 58 BC3 8 MAN FA . ? MAN B 1454 . ? 1_555 ? 59 BC4 5 PHE B 26 ? PHE B 241 . ? 1_555 ? 60 BC4 5 PHE B 28 ? PHE B 243 . ? 1_555 ? 61 BC4 5 NAG DA . ? NAG B 1452 . ? 1_555 ? 62 BC4 5 MAN FA . ? MAN B 1454 . ? 1_555 ? 63 BC4 5 BMA IA . ? BMA B 1457 . ? 1_555 ? 64 BC5 6 PHE B 28 ? PHE B 243 . ? 1_555 ? 65 BC5 6 ARG B 86 ? ARG B 301 . ? 1_555 ? 66 BC5 6 FUL CA . ? FUL B 1451 . ? 1_555 ? 67 BC5 6 NAG DA . ? NAG B 1452 . ? 1_555 ? 68 BC5 6 BMA EA . ? BMA B 1453 . ? 1_555 ? 69 BC5 6 NAG GA . ? NAG B 1455 . ? 1_555 ? 70 BC6 6 PHE B 28 ? PHE B 243 . ? 1_555 ? 71 BC6 6 LYS B 31 ? LYS B 246 . ? 1_555 ? 72 BC6 6 THR B 45 ? THR B 260 . ? 1_555 ? 73 BC6 6 ARG B 86 ? ARG B 301 . ? 1_555 ? 74 BC6 6 MAN FA . ? MAN B 1454 . ? 1_555 ? 75 BC6 6 GAL HA . ? GAL B 1456 . ? 1_555 ? 76 BC7 6 PRO B 30 ? PRO B 245 . ? 1_555 ? 77 BC7 6 LYS B 31 ? LYS B 246 . ? 1_555 ? 78 BC7 6 ASP B 34 ? ASP B 249 . ? 1_555 ? 79 BC7 6 GLU B 43 ? GLU B 258 . ? 1_555 ? 80 BC7 6 THR B 45 ? THR B 260 . ? 1_555 ? 81 BC7 6 NAG GA . ? NAG B 1455 . ? 1_555 ? 82 BC8 3 PHE B 26 ? PHE B 241 . ? 1_555 ? 83 BC8 3 BMA EA . ? BMA B 1453 . ? 1_555 ? 84 BC8 3 NAG JA . ? NAG B 1458 . ? 1_555 ? 85 BC9 2 LYS B 119 ? LYS B 334 . ? 1_555 ? 86 BC9 2 BMA IA . ? BMA B 1457 . ? 1_555 ? 87 CC1 5 HIS A 53 ? HIS A 268 . ? 1_555 ? 88 CC1 5 GLU A 79 ? GLU A 294 . ? 1_555 ? 89 CC1 5 TYR A 85 ? TYR A 300 . ? 1_555 ? 90 CC1 5 HIS A 95 ? HIS A 310 . ? 1_555 ? 91 CC1 5 HIS A 220 ? HIS A 435 . ? 1_555 ? 92 CC2 4 GLU A 57 ? GLU A 272 . ? 1_555 ? 93 CC2 4 GLU A 130 ? GLU A 345 . ? 1_555 ? 94 CC2 4 HIS A 218 ? HIS A 433 . ? 1_555 ? 95 CC2 4 CAC I . ? CAC A 1447 . ? 1_555 ? 96 CC3 4 GLU A 57 ? GLU A 272 . ? 1_555 ? 97 CC3 4 GLU A 130 ? GLU A 345 . ? 1_555 ? 98 CC3 4 HIS A 218 ? HIS A 433 . ? 1_555 ? 99 CC3 4 ZN H . ? ZN A 1446 . ? 1_555 ? 100 CC4 7 LYS A 155 ? LYS A 370 . ? 1_555 ? 101 CC4 7 ASP A 184 ? ASP A 399 . ? 1_555 ? 102 CC4 7 SER A 185 ? SER A 400 . ? 1_555 ? 103 CC4 7 ASP A 186 ? ASP A 401 . ? 1_555 ? 104 CC4 7 ASN B 175 ? ASN B 390 . ? 1_555 ? 105 CC4 7 THR B 196 ? THR B 411 . ? 1_555 ? 106 CC4 7 SER D 26 ? SER I 15 . ? 1_555 ? 107 CC5 4 VAL A 69 ? VAL A 284 . ? 1_555 ? 108 CC5 4 ASN A 71 ? ASN A 286 . ? 1_555 ? 109 CC5 4 LEU A 91 ? LEU A 306 . ? 1_555 ? 110 CC5 4 THR A 92 ? THR A 307 . ? 1_555 ? 111 CC6 3 HIS B 53 ? HIS B 268 . ? 1_555 ? 112 CC6 3 GLU B 79 ? GLU B 294 . ? 1_555 ? 113 CC6 3 HIS F 211 ? HIS M 188 . ? 1_555 ? 114 CC7 4 GLN B 132 ? GLN B 347 . ? 1_555 ? 115 CC7 4 VAL B 133 ? VAL B 348 . ? 1_555 ? 116 CC7 4 TYR B 134 ? TYR B 349 . ? 1_555 ? 117 CC7 4 ASN D 69 ? ASN I 56 . ? 1_555 ? 118 CC8 1 GLY C 57 ? GLY H 44 . ? 1_555 ? 119 CC9 7 PRO A 56 ? PRO A 271 . ? 1_555 ? 120 CC9 7 VAL A 58 ? VAL A 273 . ? 1_555 ? 121 CC9 7 LYS A 75 ? LYS A 290 . ? 1_555 ? 122 CC9 7 PRO A 76 ? PRO A 291 . ? 1_555 ? 123 CC9 7 ARG A 77 ? ARG A 292 . ? 1_555 ? 124 CC9 7 VAL A 87 ? VAL A 302 . ? 1_555 ? 125 CC9 7 HOH MA . ? HOH A 2029 . ? 1_555 ? 126 DC1 4 ILE A 162 ? ILE A 377 . ? 1_555 ? 127 DC1 4 ALA A 163 ? ALA A 378 . ? 1_555 ? 128 DC1 4 VAL A 164 ? VAL A 379 . ? 1_555 ? 129 DC1 4 MPD L . ? MPD A 1450 . ? 1_555 ? 130 DC2 6 ILE A 162 ? ILE A 377 . ? 1_555 ? 131 DC2 6 THR A 179 ? THR A 394 . ? 1_555 ? 132 DC2 6 PRO A 180 ? PRO A 395 . ? 1_555 ? 133 DC2 6 PRO A 181 ? PRO A 396 . ? 1_555 ? 134 DC2 6 LEU A 191 ? LEU A 406 . ? 1_555 ? 135 DC2 6 MPD K . ? MPD A 1449 . ? 1_555 ? 136 DC3 1 HIS B 218 ? HIS B 433 . ? 1_555 ? 137 DC4 3 TYR B 176 ? TYR B 391 . ? 1_555 ? 138 DC4 3 LYS B 177 ? LYS B 392 . ? 1_555 ? 139 DC4 3 THR B 178 ? THR B 393 . ? 1_555 ? 140 DC5 6 GLY D 55 ? GLY I 42 . ? 1_555 ? 141 DC5 6 GLY D 57 ? GLY I 44 . ? 1_555 ? 142 DC5 6 ASP F 105 ? ASP M 85 . ? 1_555 ? 143 DC5 6 TYR F 107 ? TYR M 87 . ? 1_555 ? 144 DC5 6 GLY F 122 ? GLY M 100 . ? 1_555 ? 145 DC5 6 LYS F 125 ? LYS M 103 . ? 1_555 ? # _database_PDB_matrix.entry_id 2J6E _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2J6E _atom_sites.fract_transf_matrix[1][1] 0.004133 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000082 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.013226 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.009768 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol AS C CD N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLY A 1 21 ? 34.885 29.535 51.516 1.00 61.39 ? 236 GLY A N 1 ATOM 2 C CA . GLY A 1 21 ? 35.874 29.809 50.416 1.00 61.29 ? 236 GLY A CA 1 ATOM 3 C C . GLY A 1 21 ? 37.179 30.381 50.944 1.00 60.34 ? 236 GLY A C 1 ATOM 4 O O . GLY A 1 21 ? 37.683 31.401 50.445 1.00 58.84 ? 236 GLY A O 1 ATOM 5 N N . GLY A 1 22 ? 37.731 29.711 51.955 1.00 58.71 ? 237 GLY A N 1 ATOM 6 C CA . GLY A 1 22 ? 38.971 30.165 52.559 1.00 54.89 ? 237 GLY A CA 1 ATOM 7 C C . GLY A 1 22 ? 40.176 30.046 51.651 1.00 51.62 ? 237 GLY A C 1 ATOM 8 O O . GLY A 1 22 ? 40.072 30.176 50.434 1.00 50.61 ? 237 GLY A O 1 ATOM 9 N N . PRO A 1 23 ? 41.356 29.828 52.227 1.00 49.45 ? 238 PRO A N 1 ATOM 10 C CA . PRO A 1 23 ? 42.538 29.701 51.382 1.00 48.72 ? 238 PRO A CA 1 ATOM 11 C C . PRO A 1 23 ? 42.558 28.290 50.832 1.00 48.22 ? 238 PRO A C 1 ATOM 12 O O . PRO A 1 23 ? 41.777 27.453 51.263 1.00 49.66 ? 238 PRO A O 1 ATOM 13 C CB . PRO A 1 23 ? 43.673 29.960 52.359 1.00 48.14 ? 238 PRO A CB 1 ATOM 14 C CG . PRO A 1 23 ? 43.138 29.366 53.624 1.00 47.94 ? 238 PRO A CG 1 ATOM 15 C CD . PRO A 1 23 ? 41.725 29.869 53.652 1.00 48.17 ? 238 PRO A CD 1 ATOM 16 N N . SER A 1 24 ? 43.422 28.023 49.867 1.00 47.75 ? 239 SER A N 1 ATOM 17 C CA . SER A 1 24 ? 43.519 26.675 49.329 1.00 48.39 ? 239 SER A CA 1 ATOM 18 C C . SER A 1 24 ? 44.988 26.283 49.443 1.00 47.95 ? 239 SER A C 1 ATOM 19 O O . SER A 1 24 ? 45.866 27.149 49.449 1.00 47.76 ? 239 SER A O 1 ATOM 20 C CB . SER A 1 24 ? 43.005 26.601 47.871 1.00 48.58 ? 239 SER A CB 1 ATOM 21 O OG . SER A 1 24 ? 43.763 27.385 46.965 1.00 49.87 ? 239 SER A OG 1 ATOM 22 N N . VAL A 1 25 ? 45.252 24.985 49.548 1.00 45.66 ? 240 VAL A N 1 ATOM 23 C CA . VAL A 1 25 ? 46.613 24.513 49.716 1.00 43.02 ? 240 VAL A CA 1 ATOM 24 C C . VAL A 1 25 ? 47.177 23.763 48.523 1.00 42.88 ? 240 VAL A C 1 ATOM 25 O O . VAL A 1 25 ? 46.439 23.326 47.650 1.00 45.48 ? 240 VAL A O 1 ATOM 26 C CB . VAL A 1 25 ? 46.680 23.610 50.936 1.00 42.72 ? 240 VAL A CB 1 ATOM 27 C CG1 . VAL A 1 25 ? 48.130 23.330 51.305 1.00 42.29 ? 240 VAL A CG1 1 ATOM 28 C CG2 . VAL A 1 25 ? 45.909 24.260 52.079 1.00 39.93 ? 240 VAL A CG2 1 ATOM 29 N N . PHE A 1 26 ? 48.497 23.617 48.498 1.00 40.98 ? 241 PHE A N 1 ATOM 30 C CA . PHE A 1 26 ? 49.200 22.913 47.427 1.00 39.59 ? 241 PHE A CA 1 ATOM 31 C C . PHE A 1 26 ? 50.428 22.272 48.038 1.00 40.08 ? 241 PHE A C 1 ATOM 32 O O . PHE A 1 26 ? 51.156 22.916 48.785 1.00 42.87 ? 241 PHE A O 1 ATOM 33 C CB . PHE A 1 26 ? 49.593 23.895 46.336 1.00 36.39 ? 241 PHE A CB 1 ATOM 34 C CG . PHE A 1 26 ? 48.422 24.548 45.699 1.00 36.59 ? 241 PHE A CG 1 ATOM 35 C CD1 . PHE A 1 26 ? 47.647 23.861 44.780 1.00 37.75 ? 241 PHE A CD1 1 ATOM 36 C CD2 . PHE A 1 26 ? 48.044 25.825 46.060 1.00 37.15 ? 241 PHE A CD2 1 ATOM 37 C CE1 . PHE A 1 26 ? 46.508 24.441 44.228 1.00 37.54 ? 241 PHE A CE1 1 ATOM 38 C CE2 . PHE A 1 26 ? 46.908 26.412 45.516 1.00 38.81 ? 241 PHE A CE2 1 ATOM 39 C CZ . PHE A 1 26 ? 46.139 25.715 44.596 1.00 38.41 ? 241 PHE A CZ 1 ATOM 40 N N . LEU A 1 27 ? 50.648 21.000 47.734 1.00 38.28 ? 242 LEU A N 1 ATOM 41 C CA . LEU A 1 27 ? 51.770 20.266 48.292 1.00 36.07 ? 242 LEU A CA 1 ATOM 42 C C . LEU A 1 27 ? 52.688 19.805 47.174 1.00 36.76 ? 242 LEU A C 1 ATOM 43 O O . LEU A 1 27 ? 52.341 18.907 46.418 1.00 37.75 ? 242 LEU A O 1 ATOM 44 C CB . LEU A 1 27 ? 51.220 19.077 49.068 1.00 34.67 ? 242 LEU A CB 1 ATOM 45 C CG . LEU A 1 27 ? 52.176 18.110 49.737 1.00 34.97 ? 242 LEU A CG 1 ATOM 46 C CD1 . LEU A 1 27 ? 52.977 18.857 50.768 1.00 36.49 ? 242 LEU A CD1 1 ATOM 47 C CD2 . LEU A 1 27 ? 51.391 16.960 50.372 1.00 32.76 ? 242 LEU A CD2 1 ATOM 48 N N . PHE A 1 28 ? 53.862 20.420 47.074 1.00 36.81 ? 243 PHE A N 1 ATOM 49 C CA . PHE A 1 28 ? 54.834 20.098 46.019 1.00 34.63 ? 243 PHE A CA 1 ATOM 50 C C . PHE A 1 28 ? 55.892 19.094 46.442 1.00 30.84 ? 243 PHE A C 1 ATOM 51 O O . PHE A 1 28 ? 56.274 19.050 47.593 1.00 29.47 ? 243 PHE A O 1 ATOM 52 C CB . PHE A 1 28 ? 55.510 21.386 45.560 1.00 36.68 ? 243 PHE A CB 1 ATOM 53 C CG . PHE A 1 28 ? 54.541 22.453 45.186 1.00 37.95 ? 243 PHE A CG 1 ATOM 54 C CD1 . PHE A 1 28 ? 54.044 22.532 43.892 1.00 37.46 ? 243 PHE A CD1 1 ATOM 55 C CD2 . PHE A 1 28 ? 54.050 23.328 46.154 1.00 39.61 ? 243 PHE A CD2 1 ATOM 56 C CE1 . PHE A 1 28 ? 53.063 23.465 43.564 1.00 39.48 ? 243 PHE A CE1 1 ATOM 57 C CE2 . PHE A 1 28 ? 53.068 24.264 45.840 1.00 40.40 ? 243 PHE A CE2 1 ATOM 58 C CZ . PHE A 1 28 ? 52.570 24.334 44.540 1.00 40.00 ? 243 PHE A CZ 1 ATOM 59 N N . PRO A 1 29 ? 56.382 18.278 45.503 1.00 30.11 ? 244 PRO A N 1 ATOM 60 C CA . PRO A 1 29 ? 57.405 17.273 45.809 1.00 31.60 ? 244 PRO A CA 1 ATOM 61 C C . PRO A 1 29 ? 58.805 17.862 45.746 1.00 31.59 ? 244 PRO A C 1 ATOM 62 O O . PRO A 1 29 ? 59.007 19.002 45.317 1.00 32.34 ? 244 PRO A O 1 ATOM 63 C CB . PRO A 1 29 ? 57.208 16.252 44.710 1.00 30.82 ? 244 PRO A CB 1 ATOM 64 C CG . PRO A 1 29 ? 56.968 17.160 43.534 1.00 29.16 ? 244 PRO A CG 1 ATOM 65 C CD . PRO A 1 29 ? 55.954 18.154 44.101 1.00 28.53 ? 244 PRO A CD 1 ATOM 66 N N . PRO A 1 30 ? 59.798 17.075 46.153 1.00 29.65 ? 245 PRO A N 1 ATOM 67 C CA . PRO A 1 30 ? 61.176 17.555 46.127 1.00 29.04 ? 245 PRO A CA 1 ATOM 68 C C . PRO A 1 30 ? 61.686 17.506 44.707 1.00 27.74 ? 245 PRO A C 1 ATOM 69 O O . PRO A 1 30 ? 61.156 16.768 43.897 1.00 28.98 ? 245 PRO A O 1 ATOM 70 C CB . PRO A 1 30 ? 61.891 16.566 47.044 1.00 29.53 ? 245 PRO A CB 1 ATOM 71 C CG . PRO A 1 30 ? 61.177 15.279 46.748 1.00 29.81 ? 245 PRO A CG 1 ATOM 72 C CD . PRO A 1 30 ? 59.714 15.718 46.720 1.00 30.39 ? 245 PRO A CD 1 ATOM 73 N N . LYS A 1 31 ? 62.699 18.297 44.395 1.00 28.21 ? 246 LYS A N 1 ATOM 74 C CA . LYS A 1 31 ? 63.264 18.277 43.054 1.00 30.79 ? 246 LYS A CA 1 ATOM 75 C C . LYS A 1 31 ? 63.903 16.910 42.839 1.00 31.56 ? 246 LYS A C 1 ATOM 76 O O . LYS A 1 31 ? 64.579 16.379 43.724 1.00 31.90 ? 246 LYS A O 1 ATOM 77 C CB . LYS A 1 31 ? 64.338 19.361 42.887 1.00 32.47 ? 246 LYS A CB 1 ATOM 78 C CG . LYS A 1 31 ? 63.807 20.782 42.829 1.00 36.49 ? 246 LYS A CG 1 ATOM 79 C CD . LYS A 1 31 ? 63.008 21.032 41.548 1.00 40.65 ? 246 LYS A CD 1 ATOM 80 C CE . LYS A 1 31 ? 62.404 22.451 41.505 1.00 40.63 ? 246 LYS A CE 1 ATOM 81 N NZ . LYS A 1 31 ? 61.574 22.721 42.704 1.00 35.34 ? 246 LYS A NZ 1 ATOM 82 N N . PRO A 1 32 ? 63.711 16.323 41.652 1.00 31.16 ? 247 PRO A N 1 ATOM 83 C CA . PRO A 1 32 ? 64.285 15.017 41.359 1.00 32.67 ? 247 PRO A CA 1 ATOM 84 C C . PRO A 1 32 ? 65.768 14.918 41.684 1.00 34.36 ? 247 PRO A C 1 ATOM 85 O O . PRO A 1 32 ? 66.218 13.917 42.226 1.00 34.12 ? 247 PRO A O 1 ATOM 86 C CB . PRO A 1 32 ? 64.003 14.855 39.876 1.00 31.05 ? 247 PRO A CB 1 ATOM 87 C CG . PRO A 1 32 ? 62.711 15.533 39.741 1.00 32.08 ? 247 PRO A CG 1 ATOM 88 C CD . PRO A 1 32 ? 62.949 16.807 40.499 1.00 30.90 ? 247 PRO A CD 1 ATOM 89 N N . LYS A 1 33 ? 66.525 15.958 41.362 1.00 36.38 ? 248 LYS A N 1 ATOM 90 C CA . LYS A 1 33 ? 67.954 15.939 41.625 1.00 38.49 ? 248 LYS A CA 1 ATOM 91 C C . LYS A 1 33 ? 68.269 15.790 43.121 1.00 39.85 ? 248 LYS A C 1 ATOM 92 O O . LYS A 1 33 ? 69.086 14.964 43.519 1.00 40.67 ? 248 LYS A O 1 ATOM 93 C CB . LYS A 1 33 ? 68.604 17.213 41.086 1.00 38.27 ? 248 LYS A CB 1 ATOM 94 C CG . LYS A 1 33 ? 70.083 17.049 40.829 1.00 41.55 ? 248 LYS A CG 1 ATOM 95 C CD . LYS A 1 33 ? 70.877 18.232 41.348 1.00 44.69 ? 248 LYS A CD 1 ATOM 96 C CE . LYS A 1 33 ? 72.332 18.172 40.886 1.00 44.12 ? 248 LYS A CE 1 ATOM 97 N NZ . LYS A 1 33 ? 72.455 18.368 39.410 1.00 42.16 ? 248 LYS A NZ 1 ATOM 98 N N . ASP A 1 34 ? 67.620 16.587 43.956 1.00 39.72 ? 249 ASP A N 1 ATOM 99 C CA . ASP A 1 34 ? 67.876 16.516 45.377 1.00 39.65 ? 249 ASP A CA 1 ATOM 100 C C . ASP A 1 34 ? 67.554 15.167 46.004 1.00 39.57 ? 249 ASP A C 1 ATOM 101 O O . ASP A 1 34 ? 67.929 14.913 47.146 1.00 40.38 ? 249 ASP A O 1 ATOM 102 C CB . ASP A 1 34 ? 67.084 17.595 46.104 1.00 43.80 ? 249 ASP A CB 1 ATOM 103 C CG . ASP A 1 34 ? 67.658 18.963 45.905 1.00 46.97 ? 249 ASP A CG 1 ATOM 104 O OD1 . ASP A 1 34 ? 67.546 19.487 44.786 1.00 50.71 ? 249 ASP A OD1 1 ATOM 105 O OD2 . ASP A 1 34 ? 68.231 19.517 46.868 1.00 52.39 ? 249 ASP A OD2 1 ATOM 106 N N . THR A 1 35 ? 66.845 14.301 45.293 1.00 38.03 ? 250 THR A N 1 ATOM 107 C CA . THR A 1 35 ? 66.516 13.009 45.885 1.00 36.05 ? 250 THR A CA 1 ATOM 108 C C . THR A 1 35 ? 67.382 11.864 45.388 1.00 33.43 ? 250 THR A C 1 ATOM 109 O O . THR A 1 35 ? 67.365 10.791 45.966 1.00 32.00 ? 250 THR A O 1 ATOM 110 C CB . THR A 1 35 ? 65.009 12.638 45.677 1.00 37.05 ? 250 THR A CB 1 ATOM 111 O OG1 . THR A 1 35 ? 64.747 12.378 44.291 1.00 35.46 ? 250 THR A OG1 1 ATOM 112 C CG2 . THR A 1 35 ? 64.114 13.775 46.156 1.00 36.80 ? 250 THR A CG2 1 ATOM 113 N N . LEU A 1 36 ? 68.148 12.100 44.333 1.00 33.74 ? 251 LEU A N 1 ATOM 114 C CA . LEU A 1 36 ? 68.994 11.068 43.756 1.00 36.30 ? 251 LEU A CA 1 ATOM 115 C C . LEU A 1 36 ? 70.459 11.274 44.140 1.00 39.66 ? 251 LEU A C 1 ATOM 116 O O . LEU A 1 36 ? 71.294 10.373 44.006 1.00 40.33 ? 251 LEU A O 1 ATOM 117 C CB . LEU A 1 36 ? 68.847 11.068 42.236 1.00 34.21 ? 251 LEU A CB 1 ATOM 118 C CG . LEU A 1 36 ? 67.416 11.285 41.742 1.00 36.26 ? 251 LEU A CG 1 ATOM 119 C CD1 . LEU A 1 36 ? 67.355 11.211 40.223 1.00 33.96 ? 251 LEU A CD1 1 ATOM 120 C CD2 . LEU A 1 36 ? 66.507 10.248 42.383 1.00 37.10 ? 251 LEU A CD2 1 ATOM 121 N N . MET A 1 37 ? 70.773 12.466 44.619 1.00 43.02 ? 252 MET A N 1 ATOM 122 C CA . MET A 1 37 ? 72.132 12.760 45.033 1.00 47.03 ? 252 MET A CA 1 ATOM 123 C C . MET A 1 37 ? 72.085 12.791 46.562 1.00 47.89 ? 252 MET A C 1 ATOM 124 O O . MET A 1 37 ? 71.844 13.825 47.187 1.00 47.82 ? 252 MET A O 1 ATOM 125 C CB . MET A 1 37 ? 72.580 14.096 44.433 1.00 49.16 ? 252 MET A CB 1 ATOM 126 C CG . MET A 1 37 ? 74.080 14.289 44.346 1.00 53.41 ? 252 MET A CG 1 ATOM 127 S SD . MET A 1 37 ? 74.477 15.736 43.306 1.00 61.78 ? 252 MET A SD 1 ATOM 128 C CE . MET A 1 37 ? 74.996 14.897 41.749 1.00 59.57 ? 252 MET A CE 1 ATOM 129 N N . ILE A 1 38 ? 72.290 11.616 47.142 1.00 48.49 ? 253 ILE A N 1 ATOM 130 C CA . ILE A 1 38 ? 72.256 11.410 48.580 1.00 50.48 ? 253 ILE A CA 1 ATOM 131 C C . ILE A 1 38 ? 72.844 12.522 49.446 1.00 51.11 ? 253 ILE A C 1 ATOM 132 O O . ILE A 1 38 ? 72.382 12.754 50.562 1.00 51.38 ? 253 ILE A O 1 ATOM 133 C CB . ILE A 1 38 ? 72.945 10.091 48.920 1.00 50.87 ? 253 ILE A CB 1 ATOM 134 C CG1 . ILE A 1 38 ? 72.682 9.722 50.376 1.00 51.29 ? 253 ILE A CG1 1 ATOM 135 C CG2 . ILE A 1 38 ? 74.424 10.200 48.624 1.00 51.88 ? 253 ILE A CG2 1 ATOM 136 C CD1 . ILE A 1 38 ? 72.868 8.236 50.643 1.00 53.95 ? 253 ILE A CD1 1 ATOM 137 N N . SER A 1 39 ? 73.856 13.209 48.928 1.00 52.29 ? 254 SER A N 1 ATOM 138 C CA . SER A 1 39 ? 74.517 14.297 49.648 1.00 51.60 ? 254 SER A CA 1 ATOM 139 C C . SER A 1 39 ? 73.706 15.600 49.749 1.00 52.41 ? 254 SER A C 1 ATOM 140 O O . SER A 1 39 ? 74.148 16.548 50.393 1.00 54.70 ? 254 SER A O 1 ATOM 141 C CB . SER A 1 39 ? 75.851 14.606 48.982 1.00 50.21 ? 254 SER A CB 1 ATOM 142 O OG . SER A 1 39 ? 75.642 15.075 47.658 1.00 51.27 ? 254 SER A OG 1 ATOM 143 N N . ARG A 1 40 ? 72.536 15.671 49.122 1.00 51.04 ? 255 ARG A N 1 ATOM 144 C CA . ARG A 1 40 ? 71.741 16.895 49.202 1.00 49.28 ? 255 ARG A CA 1 ATOM 145 C C . ARG A 1 40 ? 70.587 16.722 50.188 1.00 47.94 ? 255 ARG A C 1 ATOM 146 O O . ARG A 1 40 ? 70.496 15.686 50.853 1.00 47.25 ? 255 ARG A O 1 ATOM 147 C CB . ARG A 1 40 ? 71.205 17.267 47.820 1.00 49.70 ? 255 ARG A CB 1 ATOM 148 C CG . ARG A 1 40 ? 72.254 17.240 46.742 1.00 49.70 ? 255 ARG A CG 1 ATOM 149 C CD . ARG A 1 40 ? 71.612 17.240 45.375 1.00 53.52 ? 255 ARG A CD 1 ATOM 150 N NE . ARG A 1 40 ? 71.050 18.535 45.014 1.00 55.66 ? 255 ARG A NE 1 ATOM 151 C CZ . ARG A 1 40 ? 71.780 19.597 44.690 1.00 56.53 ? 255 ARG A CZ 1 ATOM 152 N NH1 . ARG A 1 40 ? 73.106 19.517 44.688 1.00 56.72 ? 255 ARG A NH1 1 ATOM 153 N NH2 . ARG A 1 40 ? 71.184 20.730 44.342 1.00 56.91 ? 255 ARG A NH2 1 ATOM 154 N N . THR A 1 41 ? 69.709 17.726 50.275 1.00 46.13 ? 256 THR A N 1 ATOM 155 C CA . THR A 1 41 ? 68.575 17.678 51.201 1.00 45.18 ? 256 THR A CA 1 ATOM 156 C C . THR A 1 41 ? 67.225 17.976 50.581 1.00 42.70 ? 256 THR A C 1 ATOM 157 O O . THR A 1 41 ? 66.789 19.125 50.512 1.00 41.55 ? 256 THR A O 1 ATOM 158 C CB . THR A 1 41 ? 68.748 18.644 52.416 1.00 46.41 ? 256 THR A CB 1 ATOM 159 O OG1 . THR A 1 41 ? 69.158 19.935 51.954 1.00 49.00 ? 256 THR A OG1 1 ATOM 160 C CG2 . THR A 1 41 ? 69.776 18.104 53.402 1.00 47.59 ? 256 THR A CG2 1 ATOM 161 N N . PRO A 1 42 ? 66.534 16.925 50.140 1.00 41.48 ? 257 PRO A N 1 ATOM 162 C CA . PRO A 1 42 ? 65.215 17.015 49.520 1.00 40.47 ? 257 PRO A CA 1 ATOM 163 C C . PRO A 1 42 ? 64.167 17.412 50.540 1.00 40.28 ? 257 PRO A C 1 ATOM 164 O O . PRO A 1 42 ? 64.308 17.105 51.720 1.00 40.36 ? 257 PRO A O 1 ATOM 165 C CB . PRO A 1 42 ? 65.006 15.606 48.979 1.00 40.60 ? 257 PRO A CB 1 ATOM 166 C CG . PRO A 1 42 ? 65.788 14.771 49.920 1.00 40.46 ? 257 PRO A CG 1 ATOM 167 C CD . PRO A 1 42 ? 67.043 15.546 50.084 1.00 40.22 ? 257 PRO A CD 1 ATOM 168 N N . GLU A 1 43 ? 63.104 18.071 50.086 1.00 41.37 ? 258 GLU A N 1 ATOM 169 C CA . GLU A 1 43 ? 62.046 18.519 51.000 1.00 42.05 ? 258 GLU A CA 1 ATOM 170 C C . GLU A 1 43 ? 60.696 18.785 50.331 1.00 40.06 ? 258 GLU A C 1 ATOM 171 O O . GLU A 1 43 ? 60.651 19.224 49.193 1.00 41.33 ? 258 GLU A O 1 ATOM 172 C CB . GLU A 1 43 ? 62.498 19.804 51.673 1.00 43.81 ? 258 GLU A CB 1 ATOM 173 C CG . GLU A 1 43 ? 62.878 20.870 50.666 1.00 47.29 ? 258 GLU A CG 1 ATOM 174 C CD . GLU A 1 43 ? 63.253 22.179 51.317 1.00 51.30 ? 258 GLU A CD 1 ATOM 175 O OE1 . GLU A 1 43 ? 62.398 22.755 52.023 1.00 53.45 ? 258 GLU A OE1 1 ATOM 176 O OE2 . GLU A 1 43 ? 64.401 22.636 51.126 1.00 53.46 ? 258 GLU A OE2 1 ATOM 177 N N . VAL A 1 44 ? 59.594 18.535 51.034 1.00 37.11 ? 259 VAL A N 1 ATOM 178 C CA . VAL A 1 44 ? 58.278 18.809 50.458 1.00 34.59 ? 259 VAL A CA 1 ATOM 179 C C . VAL A 1 44 ? 57.823 20.180 50.914 1.00 35.04 ? 259 VAL A C 1 ATOM 180 O O . VAL A 1 44 ? 58.092 20.587 52.033 1.00 37.66 ? 259 VAL A O 1 ATOM 181 C CB . VAL A 1 44 ? 57.229 17.790 50.876 1.00 30.62 ? 259 VAL A CB 1 ATOM 182 C CG1 . VAL A 1 44 ? 57.624 16.427 50.400 1.00 31.05 ? 259 VAL A CG1 1 ATOM 183 C CG2 . VAL A 1 44 ? 57.082 17.795 52.344 1.00 32.94 ? 259 VAL A CG2 1 ATOM 184 N N . THR A 1 45 ? 57.127 20.890 50.042 1.00 34.97 ? 260 THR A N 1 ATOM 185 C CA . THR A 1 45 ? 56.671 22.230 50.344 1.00 33.03 ? 260 THR A CA 1 ATOM 186 C C . THR A 1 45 ? 55.167 22.265 50.367 1.00 32.42 ? 260 THR A C 1 ATOM 187 O O . THR A 1 45 ? 54.517 21.825 49.429 1.00 32.30 ? 260 THR A O 1 ATOM 188 C CB . THR A 1 45 ? 57.153 23.200 49.271 1.00 35.44 ? 260 THR A CB 1 ATOM 189 O OG1 . THR A 1 45 ? 58.269 22.623 48.572 1.00 36.55 ? 260 THR A OG1 1 ATOM 190 C CG2 . THR A 1 45 ? 57.568 24.518 49.901 1.00 36.35 ? 260 THR A CG2 1 ATOM 191 N N . CYS A 1 46 ? 54.616 22.791 51.446 1.00 32.40 ? 261 CYS A N 1 ATOM 192 C CA . CYS A 1 46 ? 53.179 22.902 51.593 1.00 34.39 ? 261 CYS A CA 1 ATOM 193 C C . CYS A 1 46 ? 52.874 24.382 51.486 1.00 34.98 ? 261 CYS A C 1 ATOM 194 O O . CYS A 1 46 ? 53.201 25.147 52.381 1.00 37.44 ? 261 CYS A O 1 ATOM 195 C CB . CYS A 1 46 ? 52.755 22.386 52.956 1.00 36.51 ? 261 CYS A CB 1 ATOM 196 S SG . CYS A 1 46 ? 50.976 22.046 53.097 1.00 44.31 ? 261 CYS A SG 1 ATOM 197 N N . VAL A 1 47 ? 52.246 24.792 50.394 1.00 34.26 ? 262 VAL A N 1 ATOM 198 C CA . VAL A 1 47 ? 51.947 26.201 50.187 1.00 33.89 ? 262 VAL A CA 1 ATOM 199 C C . VAL A 1 47 ? 50.499 26.579 50.419 1.00 34.76 ? 262 VAL A C 1 ATOM 200 O O . VAL A 1 47 ? 49.615 26.082 49.744 1.00 36.80 ? 262 VAL A O 1 ATOM 201 C CB . VAL A 1 47 ? 52.306 26.618 48.766 1.00 33.05 ? 262 VAL A CB 1 ATOM 202 C CG1 . VAL A 1 47 ? 51.900 28.052 48.540 1.00 33.39 ? 262 VAL A CG1 1 ATOM 203 C CG2 . VAL A 1 47 ? 53.803 26.408 48.526 1.00 33.67 ? 262 VAL A CG2 1 ATOM 204 N N . VAL A 1 48 ? 50.246 27.453 51.379 1.00 34.72 ? 263 VAL A N 1 ATOM 205 C CA . VAL A 1 48 ? 48.882 27.873 51.613 1.00 36.52 ? 263 VAL A CA 1 ATOM 206 C C . VAL A 1 48 ? 48.772 29.243 50.971 1.00 37.95 ? 263 VAL A C 1 ATOM 207 O O . VAL A 1 48 ? 49.539 30.147 51.276 1.00 38.78 ? 263 VAL A O 1 ATOM 208 C CB . VAL A 1 48 ? 48.554 27.973 53.107 1.00 37.67 ? 263 VAL A CB 1 ATOM 209 C CG1 . VAL A 1 48 ? 47.027 28.044 53.303 1.00 36.03 ? 263 VAL A CG1 1 ATOM 210 C CG2 . VAL A 1 48 ? 49.137 26.779 53.840 1.00 37.53 ? 263 VAL A CG2 1 ATOM 211 N N . VAL A 1 49 ? 47.819 29.383 50.061 1.00 39.18 ? 264 VAL A N 1 ATOM 212 C CA . VAL A 1 49 ? 47.628 30.629 49.346 1.00 38.94 ? 264 VAL A CA 1 ATOM 213 C C . VAL A 1 49 ? 46.210 31.125 49.628 1.00 39.66 ? 264 VAL A C 1 ATOM 214 O O . VAL A 1 49 ? 45.358 30.343 50.047 1.00 40.12 ? 264 VAL A O 1 ATOM 215 C CB . VAL A 1 49 ? 47.841 30.391 47.847 1.00 37.00 ? 264 VAL A CB 1 ATOM 216 C CG1 . VAL A 1 49 ? 46.541 29.995 47.198 1.00 37.79 ? 264 VAL A CG1 1 ATOM 217 C CG2 . VAL A 1 49 ? 48.442 31.602 47.215 1.00 36.55 ? 264 VAL A CG2 1 ATOM 218 N N . ASP A 1 50 ? 45.975 32.419 49.412 1.00 40.04 ? 265 ASP A N 1 ATOM 219 C CA . ASP A 1 50 ? 44.678 33.056 49.666 1.00 41.22 ? 265 ASP A CA 1 ATOM 220 C C . ASP A 1 50 ? 44.349 33.225 51.144 1.00 41.64 ? 265 ASP A C 1 ATOM 221 O O . ASP A 1 50 ? 43.202 33.013 51.554 1.00 42.30 ? 265 ASP A O 1 ATOM 222 C CB . ASP A 1 50 ? 43.525 32.289 49.012 1.00 43.80 ? 265 ASP A CB 1 ATOM 223 C CG . ASP A 1 50 ? 43.210 32.772 47.599 1.00 46.51 ? 265 ASP A CG 1 ATOM 224 O OD1 . ASP A 1 50 ? 43.704 33.848 47.188 1.00 46.20 ? 265 ASP A OD1 1 ATOM 225 O OD2 . ASP A 1 50 ? 42.446 32.063 46.900 1.00 49.47 ? 265 ASP A OD2 1 ATOM 226 N N . VAL A 1 51 ? 45.341 33.602 51.946 1.00 41.09 ? 266 VAL A N 1 ATOM 227 C CA . VAL A 1 51 ? 45.110 33.816 53.366 1.00 40.36 ? 266 VAL A CA 1 ATOM 228 C C . VAL A 1 51 ? 44.767 35.287 53.571 1.00 40.44 ? 266 VAL A C 1 ATOM 229 O O . VAL A 1 51 ? 45.534 36.173 53.199 1.00 41.35 ? 266 VAL A O 1 ATOM 230 C CB . VAL A 1 51 ? 46.347 33.467 54.203 1.00 41.34 ? 266 VAL A CB 1 ATOM 231 C CG1 . VAL A 1 51 ? 46.039 33.641 55.675 1.00 42.58 ? 266 VAL A CG1 1 ATOM 232 C CG2 . VAL A 1 51 ? 46.767 32.047 53.940 1.00 42.94 ? 266 VAL A CG2 1 ATOM 233 N N . SER A 1 52 ? 43.607 35.538 54.164 1.00 39.79 ? 267 SER A N 1 ATOM 234 C CA . SER A 1 52 ? 43.132 36.896 54.406 1.00 40.30 ? 267 SER A CA 1 ATOM 235 C C . SER A 1 52 ? 43.969 37.669 55.422 1.00 40.89 ? 267 SER A C 1 ATOM 236 O O . SER A 1 52 ? 44.841 37.107 56.085 1.00 41.71 ? 267 SER A O 1 ATOM 237 C CB . SER A 1 52 ? 41.699 36.848 54.917 1.00 39.43 ? 267 SER A CB 1 ATOM 238 O OG . SER A 1 52 ? 41.667 36.320 56.234 1.00 41.08 ? 267 SER A OG 1 ATOM 239 N N . HIS A 1 53 ? 43.692 38.965 55.540 1.00 39.40 ? 268 HIS A N 1 ATOM 240 C CA . HIS A 1 53 ? 44.392 39.790 56.507 1.00 37.85 ? 268 HIS A CA 1 ATOM 241 C C . HIS A 1 53 ? 43.695 39.599 57.836 1.00 38.70 ? 268 HIS A C 1 ATOM 242 O O . HIS A 1 53 ? 44.316 39.733 58.876 1.00 41.20 ? 268 HIS A O 1 ATOM 243 C CB . HIS A 1 53 ? 44.324 41.276 56.142 1.00 35.28 ? 268 HIS A CB 1 ATOM 244 C CG . HIS A 1 53 ? 45.572 41.815 55.505 1.00 33.43 ? 268 HIS A CG 1 ATOM 245 N ND1 . HIS A 1 53 ? 45.947 41.505 54.214 1.00 29.52 ? 268 HIS A ND1 1 ATOM 246 C CD2 . HIS A 1 53 ? 46.506 42.679 55.970 1.00 30.31 ? 268 HIS A CD2 1 ATOM 247 C CE1 . HIS A 1 53 ? 47.053 42.156 53.912 1.00 26.96 ? 268 HIS A CE1 1 ATOM 248 N NE2 . HIS A 1 53 ? 47.415 42.875 54.959 1.00 27.46 ? 268 HIS A NE2 1 ATOM 249 N N . GLU A 1 54 ? 42.404 39.284 57.804 1.00 38.48 ? 269 GLU A N 1 ATOM 250 C CA . GLU A 1 54 ? 41.653 39.112 59.038 1.00 40.73 ? 269 GLU A CA 1 ATOM 251 C C . GLU A 1 54 ? 42.133 37.942 59.879 1.00 41.20 ? 269 GLU A C 1 ATOM 252 O O . GLU A 1 54 ? 42.064 38.001 61.094 1.00 42.88 ? 269 GLU A O 1 ATOM 253 C CB . GLU A 1 54 ? 40.161 38.937 58.761 1.00 44.50 ? 269 GLU A CB 1 ATOM 254 C CG . GLU A 1 54 ? 39.501 40.099 58.055 1.00 50.68 ? 269 GLU A CG 1 ATOM 255 C CD . GLU A 1 54 ? 39.965 40.241 56.611 1.00 56.96 ? 269 GLU A CD 1 ATOM 256 O OE1 . GLU A 1 54 ? 39.742 39.302 55.806 1.00 58.60 ? 269 GLU A OE1 1 ATOM 257 O OE2 . GLU A 1 54 ? 40.551 41.297 56.275 1.00 60.94 ? 269 GLU A OE2 1 ATOM 258 N N . GLU A 1 55 ? 42.603 36.874 59.246 1.00 41.14 ? 270 GLU A N 1 ATOM 259 C CA . GLU A 1 55 ? 43.088 35.712 59.990 1.00 40.56 ? 270 GLU A CA 1 ATOM 260 C C . GLU A 1 55 ? 44.312 35.192 59.285 1.00 38.75 ? 270 GLU A C 1 ATOM 261 O O . GLU A 1 55 ? 44.267 34.180 58.609 1.00 40.90 ? 270 GLU A O 1 ATOM 262 C CB . GLU A 1 55 ? 42.039 34.605 60.033 1.00 42.38 ? 270 GLU A CB 1 ATOM 263 C CG . GLU A 1 55 ? 40.850 34.872 60.930 1.00 43.92 ? 270 GLU A CG 1 ATOM 264 C CD . GLU A 1 55 ? 39.650 35.383 60.170 1.00 47.13 ? 270 GLU A CD 1 ATOM 265 O OE1 . GLU A 1 55 ? 39.501 35.040 58.973 1.00 46.78 ? 270 GLU A OE1 1 ATOM 266 O OE2 . GLU A 1 55 ? 38.846 36.118 60.782 1.00 48.82 ? 270 GLU A OE2 1 ATOM 267 N N . PRO A 1 56 ? 45.435 35.875 59.447 1.00 37.00 ? 271 PRO A N 1 ATOM 268 C CA . PRO A 1 56 ? 46.668 35.453 58.790 1.00 36.95 ? 271 PRO A CA 1 ATOM 269 C C . PRO A 1 56 ? 47.382 34.276 59.400 1.00 36.44 ? 271 PRO A C 1 ATOM 270 O O . PRO A 1 56 ? 48.308 33.746 58.797 1.00 35.79 ? 271 PRO A O 1 ATOM 271 C CB . PRO A 1 56 ? 47.522 36.712 58.837 1.00 36.53 ? 271 PRO A CB 1 ATOM 272 C CG . PRO A 1 56 ? 47.140 37.286 60.147 1.00 36.16 ? 271 PRO A CG 1 ATOM 273 C CD . PRO A 1 56 ? 45.635 37.133 60.182 1.00 35.97 ? 271 PRO A CD 1 ATOM 274 N N . GLU A 1 57 ? 46.968 33.863 60.590 1.00 37.09 ? 272 GLU A N 1 ATOM 275 C CA . GLU A 1 57 ? 47.651 32.756 61.247 1.00 37.98 ? 272 GLU A CA 1 ATOM 276 C C . GLU A 1 57 ? 47.171 31.382 60.816 1.00 37.21 ? 272 GLU A C 1 ATOM 277 O O . GLU A 1 57 ? 46.005 31.039 60.993 1.00 38.98 ? 272 GLU A O 1 ATOM 278 C CB . GLU A 1 57 ? 47.586 32.945 62.771 1.00 37.65 ? 272 GLU A CB 1 ATOM 279 C CG . GLU A 1 57 ? 48.669 33.939 63.243 1.00 41.79 ? 272 GLU A CG 1 ATOM 280 C CD . GLU A 1 57 ? 48.323 34.733 64.510 1.00 46.03 ? 272 GLU A CD 1 ATOM 281 O OE1 . GLU A 1 57 ? 49.069 35.688 64.834 1.00 46.77 ? 272 GLU A OE1 1 ATOM 282 O OE2 . GLU A 1 57 ? 47.317 34.419 65.183 1.00 49.02 ? 272 GLU A OE2 1 ATOM 283 N N . VAL A 1 58 ? 48.088 30.614 60.221 1.00 36.02 ? 273 VAL A N 1 ATOM 284 C CA . VAL A 1 58 ? 47.801 29.259 59.738 1.00 34.36 ? 273 VAL A CA 1 ATOM 285 C C . VAL A 1 58 ? 48.746 28.256 60.396 1.00 32.81 ? 273 VAL A C 1 ATOM 286 O O . VAL A 1 58 ? 49.931 28.505 60.517 1.00 34.33 ? 273 VAL A O 1 ATOM 287 C CB . VAL A 1 58 ? 47.928 29.158 58.175 1.00 33.16 ? 273 VAL A CB 1 ATOM 288 C CG1 . VAL A 1 58 ? 47.638 30.509 57.528 1.00 32.71 ? 273 VAL A CG1 1 ATOM 289 C CG2 . VAL A 1 58 ? 49.280 28.665 57.775 1.00 32.59 ? 273 VAL A CG2 1 ATOM 290 N N . LYS A 1 59 ? 48.211 27.121 60.819 1.00 33.78 ? 274 LYS A N 1 ATOM 291 C CA . LYS A 1 59 ? 48.994 26.084 61.490 1.00 34.62 ? 274 LYS A CA 1 ATOM 292 C C . LYS A 1 59 ? 49.277 24.875 60.612 1.00 35.81 ? 274 LYS A C 1 ATOM 293 O O . LYS A 1 59 ? 48.370 24.327 59.975 1.00 37.18 ? 274 LYS A O 1 ATOM 294 C CB . LYS A 1 59 ? 48.238 25.608 62.716 1.00 35.18 ? 274 LYS A CB 1 ATOM 295 C CG . LYS A 1 59 ? 48.921 24.522 63.511 1.00 39.03 ? 274 LYS A CG 1 ATOM 296 C CD . LYS A 1 59 ? 47.923 23.926 64.484 1.00 39.82 ? 274 LYS A CD 1 ATOM 297 C CE . LYS A 1 59 ? 48.575 23.342 65.705 1.00 38.65 ? 274 LYS A CE 1 ATOM 298 N NZ . LYS A 1 59 ? 47.487 23.010 66.672 1.00 40.89 ? 274 LYS A NZ 1 ATOM 299 N N . PHE A 1 60 ? 50.532 24.442 60.591 1.00 35.26 ? 275 PHE A N 1 ATOM 300 C CA . PHE A 1 60 ? 50.893 23.284 59.799 1.00 36.19 ? 275 PHE A CA 1 ATOM 301 C C . PHE A 1 60 ? 51.032 22.056 60.674 1.00 39.19 ? 275 PHE A C 1 ATOM 302 O O . PHE A 1 60 ? 51.488 22.148 61.797 1.00 41.53 ? 275 PHE A O 1 ATOM 303 C CB . PHE A 1 60 ? 52.195 23.532 59.049 1.00 32.51 ? 275 PHE A CB 1 ATOM 304 C CG . PHE A 1 60 ? 52.087 24.601 58.014 1.00 32.08 ? 275 PHE A CG 1 ATOM 305 C CD1 . PHE A 1 60 ? 52.280 25.930 58.347 1.00 32.70 ? 275 PHE A CD1 1 ATOM 306 C CD2 . PHE A 1 60 ? 51.740 24.285 56.708 1.00 32.71 ? 275 PHE A CD2 1 ATOM 307 C CE1 . PHE A 1 60 ? 52.127 26.932 57.389 1.00 32.68 ? 275 PHE A CE1 1 ATOM 308 C CE2 . PHE A 1 60 ? 51.584 25.270 55.750 1.00 31.96 ? 275 PHE A CE2 1 ATOM 309 C CZ . PHE A 1 60 ? 51.779 26.601 56.092 1.00 32.60 ? 275 PHE A CZ 1 ATOM 310 N N . ASN A 1 61 ? 50.603 20.910 60.159 1.00 42.65 ? 276 ASN A N 1 ATOM 311 C CA . ASN A 1 61 ? 50.705 19.633 60.863 1.00 44.19 ? 276 ASN A CA 1 ATOM 312 C C . ASN A 1 61 ? 51.268 18.628 59.865 1.00 43.71 ? 276 ASN A C 1 ATOM 313 O O . ASN A 1 61 ? 50.600 18.286 58.900 1.00 44.16 ? 276 ASN A O 1 ATOM 314 C CB . ASN A 1 61 ? 49.326 19.170 61.326 1.00 47.62 ? 276 ASN A CB 1 ATOM 315 C CG . ASN A 1 61 ? 48.952 19.719 62.675 1.00 50.78 ? 276 ASN A CG 1 ATOM 316 O OD1 . ASN A 1 61 ? 49.492 19.294 63.694 1.00 53.36 ? 276 ASN A OD1 1 ATOM 317 N ND2 . ASN A 1 61 ? 48.027 20.673 62.695 1.00 53.09 ? 276 ASN A ND2 1 ATOM 318 N N . TRP A 1 62 ? 52.492 18.167 60.071 1.00 42.05 ? 277 TRP A N 1 ATOM 319 C CA . TRP A 1 62 ? 53.064 17.212 59.132 1.00 42.36 ? 277 TRP A CA 1 ATOM 320 C C . TRP A 1 62 ? 52.989 15.750 59.575 1.00 41.59 ? 277 TRP A C 1 ATOM 321 O O . TRP A 1 62 ? 52.951 15.444 60.755 1.00 40.22 ? 277 TRP A O 1 ATOM 322 C CB . TRP A 1 62 ? 54.528 17.566 58.826 1.00 42.64 ? 277 TRP A CB 1 ATOM 323 C CG . TRP A 1 62 ? 54.692 18.753 57.938 1.00 44.16 ? 277 TRP A CG 1 ATOM 324 C CD1 . TRP A 1 62 ? 54.778 20.055 58.321 1.00 44.62 ? 277 TRP A CD1 1 ATOM 325 C CD2 . TRP A 1 62 ? 54.691 18.757 56.505 1.00 44.53 ? 277 TRP A CD2 1 ATOM 326 N NE1 . TRP A 1 62 ? 54.825 20.874 57.219 1.00 43.05 ? 277 TRP A NE1 1 ATOM 327 C CE2 . TRP A 1 62 ? 54.769 20.104 56.092 1.00 43.37 ? 277 TRP A CE2 1 ATOM 328 C CE3 . TRP A 1 62 ? 54.623 17.753 55.533 1.00 44.65 ? 277 TRP A CE3 1 ATOM 329 C CZ2 . TRP A 1 62 ? 54.777 20.475 54.751 1.00 42.72 ? 277 TRP A CZ2 1 ATOM 330 C CZ3 . TRP A 1 62 ? 54.629 18.122 54.199 1.00 44.68 ? 277 TRP A CZ3 1 ATOM 331 C CH2 . TRP A 1 62 ? 54.705 19.477 53.820 1.00 43.80 ? 277 TRP A CH2 1 ATOM 332 N N . TYR A 1 63 ? 52.968 14.847 58.605 1.00 41.68 ? 278 TYR A N 1 ATOM 333 C CA . TYR A 1 63 ? 52.946 13.428 58.905 1.00 42.72 ? 278 TYR A CA 1 ATOM 334 C C . TYR A 1 63 ? 53.741 12.666 57.855 1.00 44.22 ? 278 TYR A C 1 ATOM 335 O O . TYR A 1 63 ? 53.831 13.078 56.697 1.00 46.54 ? 278 TYR A O 1 ATOM 336 C CB . TYR A 1 63 ? 51.518 12.889 58.931 1.00 42.51 ? 278 TYR A CB 1 ATOM 337 C CG . TYR A 1 63 ? 50.574 13.665 59.825 1.00 44.11 ? 278 TYR A CG 1 ATOM 338 C CD1 . TYR A 1 63 ? 49.971 14.835 59.382 1.00 41.23 ? 278 TYR A CD1 1 ATOM 339 C CD2 . TYR A 1 63 ? 50.286 13.230 61.118 1.00 43.19 ? 278 TYR A CD2 1 ATOM 340 C CE1 . TYR A 1 63 ? 49.116 15.537 60.191 1.00 40.11 ? 278 TYR A CE1 1 ATOM 341 C CE2 . TYR A 1 63 ? 49.430 13.939 61.934 1.00 39.98 ? 278 TYR A CE2 1 ATOM 342 C CZ . TYR A 1 63 ? 48.849 15.088 61.459 1.00 40.83 ? 278 TYR A CZ 1 ATOM 343 O OH . TYR A 1 63 ? 47.978 15.794 62.252 1.00 45.43 ? 278 TYR A OH 1 ATOM 344 N N . VAL A 1 64 ? 54.337 11.564 58.282 1.00 43.31 ? 279 VAL A N 1 ATOM 345 C CA . VAL A 1 64 ? 55.096 10.699 57.403 1.00 42.46 ? 279 VAL A CA 1 ATOM 346 C C . VAL A 1 64 ? 54.486 9.323 57.669 1.00 45.28 ? 279 VAL A C 1 ATOM 347 O O . VAL A 1 64 ? 54.848 8.646 58.637 1.00 45.60 ? 279 VAL A O 1 ATOM 348 C CB . VAL A 1 64 ? 56.583 10.686 57.780 1.00 40.82 ? 279 VAL A CB 1 ATOM 349 C CG1 . VAL A 1 64 ? 57.383 9.991 56.700 1.00 39.04 ? 279 VAL A CG1 1 ATOM 350 C CG2 . VAL A 1 64 ? 57.075 12.095 58.004 1.00 37.49 ? 279 VAL A CG2 1 ATOM 351 N N . ASP A 1 65 ? 53.540 8.931 56.819 1.00 47.09 ? 280 ASP A N 1 ATOM 352 C CA . ASP A 1 65 ? 52.839 7.651 56.950 1.00 48.00 ? 280 ASP A CA 1 ATOM 353 C C . ASP A 1 65 ? 52.013 7.639 58.217 1.00 49.05 ? 280 ASP A C 1 ATOM 354 O O . ASP A 1 65 ? 52.002 6.647 58.942 1.00 51.01 ? 280 ASP A O 1 ATOM 355 C CB . ASP A 1 65 ? 53.801 6.457 56.999 1.00 47.87 ? 280 ASP A CB 1 ATOM 356 C CG . ASP A 1 65 ? 54.356 6.080 55.636 1.00 49.73 ? 280 ASP A CG 1 ATOM 357 O OD1 . ASP A 1 65 ? 53.645 6.276 54.616 1.00 47.98 ? 280 ASP A OD1 1 ATOM 358 O OD2 . ASP A 1 65 ? 55.504 5.566 55.602 1.00 48.50 ? 280 ASP A OD2 1 ATOM 359 N N . GLY A 1 66 ? 51.332 8.743 58.493 1.00 49.49 ? 281 GLY A N 1 ATOM 360 C CA . GLY A 1 66 ? 50.506 8.808 59.679 1.00 49.46 ? 281 GLY A CA 1 ATOM 361 C C . GLY A 1 66 ? 51.285 9.221 60.904 1.00 49.98 ? 281 GLY A C 1 ATOM 362 O O . GLY A 1 66 ? 50.733 9.786 61.834 1.00 50.96 ? 281 GLY A O 1 ATOM 363 N N . VAL A 1 67 ? 52.577 8.944 60.928 1.00 50.66 ? 282 VAL A N 1 ATOM 364 C CA . VAL A 1 67 ? 53.360 9.333 62.089 1.00 51.20 ? 282 VAL A CA 1 ATOM 365 C C . VAL A 1 67 ? 53.735 10.820 62.030 1.00 52.66 ? 282 VAL A C 1 ATOM 366 O O . VAL A 1 67 ? 54.701 11.205 61.378 1.00 53.88 ? 282 VAL A O 1 ATOM 367 C CB . VAL A 1 67 ? 54.628 8.477 62.201 1.00 49.41 ? 282 VAL A CB 1 ATOM 368 C CG1 . VAL A 1 67 ? 55.480 8.950 63.368 1.00 48.29 ? 282 VAL A CG1 1 ATOM 369 C CG2 . VAL A 1 67 ? 54.240 7.032 62.383 1.00 46.80 ? 282 VAL A CG2 1 ATOM 370 N N . GLU A 1 68 ? 52.954 11.652 62.708 1.00 52.99 ? 283 GLU A N 1 ATOM 371 C CA . GLU A 1 68 ? 53.201 13.088 62.746 1.00 52.91 ? 283 GLU A CA 1 ATOM 372 C C . GLU A 1 68 ? 54.642 13.433 63.120 1.00 50.74 ? 283 GLU A C 1 ATOM 373 O O . GLU A 1 68 ? 55.231 12.791 63.976 1.00 50.28 ? 283 GLU A O 1 ATOM 374 C CB . GLU A 1 68 ? 52.233 13.738 63.741 1.00 55.62 ? 283 GLU A CB 1 ATOM 375 C CG . GLU A 1 68 ? 52.717 15.049 64.330 1.00 62.51 ? 283 GLU A CG 1 ATOM 376 C CD . GLU A 1 68 ? 51.591 15.857 64.949 1.00 67.14 ? 283 GLU A CD 1 ATOM 377 O OE1 . GLU A 1 68 ? 50.754 15.263 65.670 1.00 69.45 ? 283 GLU A OE1 1 ATOM 378 O OE2 . GLU A 1 68 ? 51.548 17.090 64.719 1.00 68.63 ? 283 GLU A OE2 1 ATOM 379 N N . VAL A 1 69 ? 55.202 14.448 62.468 1.00 49.26 ? 284 VAL A N 1 ATOM 380 C CA . VAL A 1 69 ? 56.562 14.886 62.751 1.00 48.99 ? 284 VAL A CA 1 ATOM 381 C C . VAL A 1 69 ? 56.556 16.341 63.182 1.00 51.36 ? 284 VAL A C 1 ATOM 382 O O . VAL A 1 69 ? 55.508 16.999 63.131 1.00 51.81 ? 284 VAL A O 1 ATOM 383 C CB . VAL A 1 69 ? 57.459 14.756 61.539 1.00 47.31 ? 284 VAL A CB 1 ATOM 384 C CG1 . VAL A 1 69 ? 57.824 13.306 61.334 1.00 47.62 ? 284 VAL A CG1 1 ATOM 385 C CG2 . VAL A 1 69 ? 56.750 15.314 60.320 1.00 46.34 ? 284 VAL A CG2 1 ATOM 386 N N . HIS A 1 70 ? 57.724 16.843 63.594 1.00 52.31 ? 285 HIS A N 1 ATOM 387 C CA . HIS A 1 70 ? 57.848 18.220 64.080 1.00 53.13 ? 285 HIS A CA 1 ATOM 388 C C . HIS A 1 70 ? 59.103 18.937 63.589 1.00 54.20 ? 285 HIS A C 1 ATOM 389 O O . HIS A 1 70 ? 59.485 19.957 64.169 1.00 56.18 ? 285 HIS A O 1 ATOM 390 C CB . HIS A 1 70 ? 57.877 18.236 65.616 1.00 52.13 ? 285 HIS A CB 1 ATOM 391 C CG . HIS A 1 70 ? 56.801 17.417 66.253 1.00 54.30 ? 285 HIS A CG 1 ATOM 392 N ND1 . HIS A 1 70 ? 55.494 17.848 66.351 1.00 55.71 ? 285 HIS A ND1 1 ATOM 393 C CD2 . HIS A 1 70 ? 56.819 16.158 66.753 1.00 54.46 ? 285 HIS A CD2 1 ATOM 394 C CE1 . HIS A 1 70 ? 54.753 16.888 66.878 1.00 54.62 ? 285 HIS A CE1 1 ATOM 395 N NE2 . HIS A 1 70 ? 55.532 15.851 67.129 1.00 54.22 ? 285 HIS A NE2 1 ATOM 396 N N . ASN A 1 71 ? 59.755 18.430 62.545 1.00 52.75 ? 286 ASN A N 1 ATOM 397 C CA . ASN A 1 71 ? 60.976 19.074 62.068 1.00 50.83 ? 286 ASN A CA 1 ATOM 398 C C . ASN A 1 71 ? 60.748 19.996 60.886 1.00 51.07 ? 286 ASN A C 1 ATOM 399 O O . ASN A 1 71 ? 61.673 20.310 60.133 1.00 51.48 ? 286 ASN A O 1 ATOM 400 C CB . ASN A 1 71 ? 62.034 18.022 61.730 1.00 49.21 ? 286 ASN A CB 1 ATOM 401 C CG . ASN A 1 71 ? 61.532 16.983 60.758 1.00 49.48 ? 286 ASN A CG 1 ATOM 402 O OD1 . ASN A 1 71 ? 60.444 16.424 60.921 1.00 48.46 ? 286 ASN A OD1 1 ATOM 403 N ND2 . ASN A 1 71 ? 62.333 16.702 59.742 1.00 50.78 ? 286 ASN A ND2 1 ATOM 404 N N . ALA A 1 72 ? 59.505 20.438 60.734 1.00 51.16 ? 287 ALA A N 1 ATOM 405 C CA . ALA A 1 72 ? 59.151 21.345 59.653 1.00 51.35 ? 287 ALA A CA 1 ATOM 406 C C . ALA A 1 72 ? 59.519 22.783 60.037 1.00 50.54 ? 287 ALA A C 1 ATOM 407 O O . ALA A 1 72 ? 59.500 23.145 61.207 1.00 49.21 ? 287 ALA A O 1 ATOM 408 C CB . ALA A 1 72 ? 57.657 21.239 59.358 1.00 49.90 ? 287 ALA A CB 1 ATOM 409 N N . LYS A 1 73 ? 59.870 23.592 59.046 1.00 50.65 ? 288 LYS A N 1 ATOM 410 C CA . LYS A 1 73 ? 60.225 24.988 59.279 1.00 50.55 ? 288 LYS A CA 1 ATOM 411 C C . LYS A 1 73 ? 59.291 25.856 58.452 1.00 49.75 ? 288 LYS A C 1 ATOM 412 O O . LYS A 1 73 ? 59.252 25.731 57.228 1.00 53.23 ? 288 LYS A O 1 ATOM 413 C CB . LYS A 1 73 ? 61.679 25.246 58.859 1.00 51.49 ? 288 LYS A CB 1 ATOM 414 C CG . LYS A 1 73 ? 62.691 24.523 59.737 1.00 56.68 ? 288 LYS A CG 1 ATOM 415 C CD . LYS A 1 73 ? 63.986 24.176 59.005 1.00 58.82 ? 288 LYS A CD 1 ATOM 416 C CE . LYS A 1 73 ? 64.911 25.371 58.828 1.00 59.71 ? 288 LYS A CE 1 ATOM 417 N NZ . LYS A 1 73 ? 66.229 24.960 58.240 1.00 58.20 ? 288 LYS A NZ 1 ATOM 418 N N . THR A 1 74 ? 58.526 26.724 59.104 1.00 46.34 ? 289 THR A N 1 ATOM 419 C CA . THR A 1 74 ? 57.618 27.612 58.378 1.00 41.88 ? 289 THR A CA 1 ATOM 420 C C . THR A 1 74 ? 58.297 28.959 58.101 1.00 39.24 ? 289 THR A C 1 ATOM 421 O O . THR A 1 74 ? 58.864 29.567 58.997 1.00 38.13 ? 289 THR A O 1 ATOM 422 C CB . THR A 1 74 ? 56.317 27.865 59.181 1.00 40.98 ? 289 THR A CB 1 ATOM 423 O OG1 . THR A 1 74 ? 55.721 26.608 59.533 1.00 41.39 ? 289 THR A OG1 1 ATOM 424 C CG2 . THR A 1 74 ? 55.330 28.693 58.367 1.00 33.97 ? 289 THR A CG2 1 ATOM 425 N N . LYS A 1 75 ? 58.262 29.406 56.852 1.00 38.67 ? 290 LYS A N 1 ATOM 426 C CA . LYS A 1 75 ? 58.849 30.693 56.495 1.00 38.94 ? 290 LYS A CA 1 ATOM 427 C C . LYS A 1 75 ? 57.817 31.739 56.911 1.00 38.16 ? 290 LYS A C 1 ATOM 428 O O . LYS A 1 75 ? 56.625 31.463 56.914 1.00 39.15 ? 290 LYS A O 1 ATOM 429 C CB . LYS A 1 75 ? 59.101 30.775 54.983 1.00 39.70 ? 290 LYS A CB 1 ATOM 430 C CG . LYS A 1 75 ? 59.876 29.594 54.415 1.00 44.09 ? 290 LYS A CG 1 ATOM 431 C CD . LYS A 1 75 ? 60.549 29.908 53.074 1.00 47.97 ? 290 LYS A CD 1 ATOM 432 C CE . LYS A 1 75 ? 59.552 30.007 51.917 1.00 52.33 ? 290 LYS A CE 1 ATOM 433 N NZ . LYS A 1 75 ? 60.187 30.417 50.612 1.00 54.16 ? 290 LYS A NZ 1 ATOM 434 N N . PRO A 1 76 ? 58.256 32.948 57.280 1.00 37.07 ? 291 PRO A N 1 ATOM 435 C CA . PRO A 1 76 ? 57.286 33.972 57.683 1.00 34.85 ? 291 PRO A CA 1 ATOM 436 C C . PRO A 1 76 ? 56.354 34.329 56.523 1.00 32.94 ? 291 PRO A C 1 ATOM 437 O O . PRO A 1 76 ? 56.797 34.480 55.386 1.00 30.70 ? 291 PRO A O 1 ATOM 438 C CB . PRO A 1 76 ? 58.173 35.128 58.125 1.00 35.91 ? 291 PRO A CB 1 ATOM 439 C CG . PRO A 1 76 ? 59.391 34.963 57.243 1.00 37.21 ? 291 PRO A CG 1 ATOM 440 C CD . PRO A 1 76 ? 59.630 33.480 57.279 1.00 37.41 ? 291 PRO A CD 1 ATOM 441 N N . ARG A 1 77 ? 55.065 34.465 56.823 1.00 32.36 ? 292 ARG A N 1 ATOM 442 C CA . ARG A 1 77 ? 54.070 34.751 55.802 1.00 33.52 ? 292 ARG A CA 1 ATOM 443 C C . ARG A 1 77 ? 54.370 35.968 54.971 1.00 34.83 ? 292 ARG A C 1 ATOM 444 O O . ARG A 1 77 ? 54.617 37.054 55.490 1.00 37.09 ? 292 ARG A O 1 ATOM 445 C CB . ARG A 1 77 ? 52.667 34.885 56.409 1.00 33.88 ? 292 ARG A CB 1 ATOM 446 C CG . ARG A 1 77 ? 52.474 36.054 57.335 1.00 33.14 ? 292 ARG A CG 1 ATOM 447 C CD . ARG A 1 77 ? 51.012 36.203 57.708 1.00 35.08 ? 292 ARG A CD 1 ATOM 448 N NE . ARG A 1 77 ? 50.824 37.054 58.884 1.00 34.85 ? 292 ARG A NE 1 ATOM 449 C CZ . ARG A 1 77 ? 50.844 36.610 60.134 1.00 32.73 ? 292 ARG A CZ 1 ATOM 450 N NH1 . ARG A 1 77 ? 51.036 35.331 60.376 1.00 35.69 ? 292 ARG A NH1 1 ATOM 451 N NH2 . ARG A 1 77 ? 50.673 37.437 61.142 1.00 33.17 ? 292 ARG A NH2 1 ATOM 452 N N . GLU A 1 78 ? 54.315 35.776 53.663 1.00 35.00 ? 293 GLU A N 1 ATOM 453 C CA . GLU A 1 78 ? 54.582 36.837 52.726 1.00 36.23 ? 293 GLU A CA 1 ATOM 454 C C . GLU A 1 78 ? 53.326 37.506 52.195 1.00 36.87 ? 293 GLU A C 1 ATOM 455 O O . GLU A 1 78 ? 52.362 36.859 51.780 1.00 36.85 ? 293 GLU A O 1 ATOM 456 C CB . GLU A 1 78 ? 55.412 36.297 51.575 1.00 39.23 ? 293 GLU A CB 1 ATOM 457 C CG . GLU A 1 78 ? 55.317 37.118 50.318 1.00 44.53 ? 293 GLU A CG 1 ATOM 458 C CD . GLU A 1 78 ? 56.067 36.490 49.168 1.00 46.98 ? 293 GLU A CD 1 ATOM 459 O OE1 . GLU A 1 78 ? 57.318 36.456 49.235 1.00 49.93 ? 293 GLU A OE1 1 ATOM 460 O OE2 . GLU A 1 78 ? 55.407 36.026 48.211 1.00 46.59 ? 293 GLU A OE2 1 ATOM 461 N N . GLU A 1 79 ? 53.388 38.830 52.206 1.00 37.03 ? 294 GLU A N 1 ATOM 462 C CA . GLU A 1 79 ? 52.334 39.727 51.762 1.00 35.30 ? 294 GLU A CA 1 ATOM 463 C C . GLU A 1 79 ? 52.222 39.625 50.246 1.00 35.08 ? 294 GLU A C 1 ATOM 464 O O . GLU A 1 79 ? 53.243 39.681 49.568 1.00 33.52 ? 294 GLU A O 1 ATOM 465 C CB . GLU A 1 79 ? 52.740 41.147 52.161 1.00 35.02 ? 294 GLU A CB 1 ATOM 466 C CG . GLU A 1 79 ? 51.623 42.156 52.263 1.00 37.77 ? 294 GLU A CG 1 ATOM 467 C CD . GLU A 1 79 ? 50.935 42.153 53.614 1.00 37.82 ? 294 GLU A CD 1 ATOM 468 O OE1 . GLU A 1 79 ? 51.588 41.893 54.649 1.00 36.99 ? 294 GLU A OE1 1 ATOM 469 O OE2 . GLU A 1 79 ? 49.730 42.439 53.638 1.00 39.21 ? 294 GLU A OE2 1 ATOM 470 N N . GLN A 1 80 ? 50.997 39.481 49.723 1.00 36.33 ? 295 GLN A N 1 ATOM 471 C CA . GLN A 1 80 ? 50.751 39.390 48.268 1.00 37.00 ? 295 GLN A CA 1 ATOM 472 C C . GLN A 1 80 ? 50.092 40.639 47.693 1.00 38.16 ? 295 GLN A C 1 ATOM 473 O O . GLN A 1 80 ? 49.394 41.361 48.396 1.00 40.72 ? 295 GLN A O 1 ATOM 474 C CB . GLN A 1 80 ? 49.844 38.213 47.932 1.00 36.84 ? 295 GLN A CB 1 ATOM 475 C CG . GLN A 1 80 ? 50.442 36.844 48.147 1.00 38.56 ? 295 GLN A CG 1 ATOM 476 C CD . GLN A 1 80 ? 51.803 36.693 47.525 1.00 36.63 ? 295 GLN A CD 1 ATOM 477 O OE1 . GLN A 1 80 ? 52.815 37.009 48.139 1.00 38.30 ? 295 GLN A OE1 1 ATOM 478 N NE2 . GLN A 1 80 ? 51.838 36.209 46.299 1.00 36.23 ? 295 GLN A NE2 1 ATOM 479 N N . TYR A 1 81 ? 50.275 40.874 46.399 1.00 39.21 ? 296 TYR A N 1 ATOM 480 C CA . TYR A 1 81 ? 49.688 42.053 45.778 1.00 38.76 ? 296 TYR A CA 1 ATOM 481 C C . TYR A 1 81 ? 48.182 42.039 45.714 1.00 39.28 ? 296 TYR A C 1 ATOM 482 O O . TYR A 1 81 ? 47.581 43.087 45.569 1.00 40.65 ? 296 TYR A O 1 ATOM 483 C CB . TYR A 1 81 ? 50.253 42.257 44.384 1.00 38.70 ? 296 TYR A CB 1 ATOM 484 C CG . TYR A 1 81 ? 51.693 42.719 44.398 1.00 40.47 ? 296 TYR A CG 1 ATOM 485 C CD1 . TYR A 1 81 ? 52.617 42.204 43.502 1.00 41.01 ? 296 TYR A CD1 1 ATOM 486 C CD2 . TYR A 1 81 ? 52.132 43.665 45.313 1.00 40.29 ? 296 TYR A CD2 1 ATOM 487 C CE1 . TYR A 1 81 ? 53.938 42.615 43.519 1.00 42.82 ? 296 TYR A CE1 1 ATOM 488 C CE2 . TYR A 1 81 ? 53.457 44.084 45.337 1.00 41.83 ? 296 TYR A CE2 1 ATOM 489 C CZ . TYR A 1 81 ? 54.355 43.554 44.438 1.00 42.99 ? 296 TYR A CZ 1 ATOM 490 O OH . TYR A 1 81 ? 55.677 43.954 44.447 1.00 45.74 ? 296 TYR A OH 1 ATOM 491 N N . ASN A 1 82 ? 47.558 40.871 45.811 1.00 39.22 ? 297 ASN A N 1 ATOM 492 C CA . ASN A 1 82 ? 46.105 40.840 45.778 1.00 39.05 ? 297 ASN A CA 1 ATOM 493 C C . ASN A 1 82 ? 45.501 40.831 47.178 1.00 41.82 ? 297 ASN A C 1 ATOM 494 O O . ASN A 1 82 ? 44.501 40.152 47.438 1.00 43.38 ? 297 ASN A O 1 ATOM 495 C CB . ASN A 1 82 ? 45.574 39.645 44.964 1.00 39.05 ? 297 ASN A CB 1 ATOM 496 C CG . ASN A 1 82 ? 46.115 38.303 45.433 1.00 37.62 ? 297 ASN A CG 1 ATOM 497 O OD1 . ASN A 1 82 ? 46.403 38.127 46.610 1.00 39.37 ? 297 ASN A OD1 1 ATOM 498 N ND2 . ASN A 1 82 ? 46.223 37.353 44.501 1.00 34.78 ? 297 ASN A ND2 1 ATOM 499 N N . SER A 1 83 ? 46.116 41.585 48.086 1.00 41.93 ? 298 SER A N 1 ATOM 500 C CA . SER A 1 83 ? 45.617 41.693 49.454 1.00 41.95 ? 298 SER A CA 1 ATOM 501 C C . SER A 1 83 ? 45.394 40.389 50.191 1.00 41.42 ? 298 SER A C 1 ATOM 502 O O . SER A 1 83 ? 44.363 40.230 50.834 1.00 43.30 ? 298 SER A O 1 ATOM 503 C CB . SER A 1 83 ? 44.294 42.475 49.482 1.00 43.71 ? 298 SER A CB 1 ATOM 504 O OG . SER A 1 83 ? 44.492 43.875 49.354 1.00 45.35 ? 298 SER A OG 1 ATOM 505 N N . THR A 1 84 ? 46.333 39.453 50.095 1.00 41.35 ? 299 THR A N 1 ATOM 506 C CA . THR A 1 84 ? 46.233 38.172 50.809 1.00 40.18 ? 299 THR A CA 1 ATOM 507 C C . THR A 1 84 ? 47.640 37.674 51.048 1.00 39.21 ? 299 THR A C 1 ATOM 508 O O . THR A 1 84 ? 48.596 38.248 50.530 1.00 38.37 ? 299 THR A O 1 ATOM 509 C CB . THR A 1 84 ? 45.478 37.044 50.019 1.00 40.67 ? 299 THR A CB 1 ATOM 510 O OG1 . THR A 1 84 ? 46.127 36.808 48.764 1.00 40.23 ? 299 THR A OG1 1 ATOM 511 C CG2 . THR A 1 84 ? 44.022 37.397 49.806 1.00 39.20 ? 299 THR A CG2 1 ATOM 512 N N . TYR A 1 85 ? 47.759 36.602 51.825 1.00 38.26 ? 300 TYR A N 1 ATOM 513 C CA . TYR A 1 85 ? 49.053 36.023 52.119 1.00 37.55 ? 300 TYR A CA 1 ATOM 514 C C . TYR A 1 85 ? 49.319 34.713 51.406 1.00 37.64 ? 300 TYR A C 1 ATOM 515 O O . TYR A 1 85 ? 48.409 34.074 50.878 1.00 38.15 ? 300 TYR A O 1 ATOM 516 C CB . TYR A 1 85 ? 49.200 35.768 53.609 1.00 38.95 ? 300 TYR A CB 1 ATOM 517 C CG . TYR A 1 85 ? 49.263 37.003 54.435 1.00 39.42 ? 300 TYR A CG 1 ATOM 518 C CD1 . TYR A 1 85 ? 48.101 37.590 54.923 1.00 41.43 ? 300 TYR A CD1 1 ATOM 519 C CD2 . TYR A 1 85 ? 50.480 37.617 54.698 1.00 38.74 ? 300 TYR A CD2 1 ATOM 520 C CE1 . TYR A 1 85 ? 48.147 38.773 55.658 1.00 42.51 ? 300 TYR A CE1 1 ATOM 521 C CE2 . TYR A 1 85 ? 50.540 38.793 55.425 1.00 41.91 ? 300 TYR A CE2 1 ATOM 522 C CZ . TYR A 1 85 ? 49.371 39.365 55.903 1.00 41.49 ? 300 TYR A CZ 1 ATOM 523 O OH . TYR A 1 85 ? 49.422 40.514 56.640 1.00 42.55 ? 300 TYR A OH 1 ATOM 524 N N . ARG A 1 86 ? 50.599 34.345 51.402 1.00 36.26 ? 301 ARG A N 1 ATOM 525 C CA . ARG A 1 86 ? 51.102 33.096 50.837 1.00 33.72 ? 301 ARG A CA 1 ATOM 526 C C . ARG A 1 86 ? 52.030 32.609 51.927 1.00 32.21 ? 301 ARG A C 1 ATOM 527 O O . ARG A 1 86 ? 53.049 33.233 52.189 1.00 32.45 ? 301 ARG A O 1 ATOM 528 C CB . ARG A 1 86 ? 51.903 33.329 49.558 1.00 32.37 ? 301 ARG A CB 1 ATOM 529 C CG . ARG A 1 86 ? 52.616 32.079 49.056 1.00 33.25 ? 301 ARG A CG 1 ATOM 530 C CD . ARG A 1 86 ? 53.018 32.236 47.609 1.00 35.81 ? 301 ARG A CD 1 ATOM 531 N NE . ARG A 1 86 ? 53.621 31.044 47.018 1.00 36.61 ? 301 ARG A NE 1 ATOM 532 C CZ . ARG A 1 86 ? 54.793 30.541 47.389 1.00 38.28 ? 301 ARG A CZ 1 ATOM 533 N NH1 . ARG A 1 86 ? 55.483 31.124 48.361 1.00 38.18 ? 301 ARG A NH1 1 ATOM 534 N NH2 . ARG A 1 86 ? 55.288 29.476 46.772 1.00 37.21 ? 301 ARG A NH2 1 ATOM 535 N N . VAL A 1 87 ? 51.663 31.511 52.574 1.00 31.98 ? 302 VAL A N 1 ATOM 536 C CA . VAL A 1 87 ? 52.448 30.956 53.673 1.00 30.81 ? 302 VAL A CA 1 ATOM 537 C C . VAL A 1 87 ? 53.118 29.680 53.213 1.00 30.32 ? 302 VAL A C 1 ATOM 538 O O . VAL A 1 87 ? 52.504 28.895 52.500 1.00 32.36 ? 302 VAL A O 1 ATOM 539 C CB . VAL A 1 87 ? 51.540 30.624 54.876 1.00 28.84 ? 302 VAL A CB 1 ATOM 540 C CG1 . VAL A 1 87 ? 52.333 30.668 56.153 1.00 25.86 ? 302 VAL A CG1 1 ATOM 541 C CG2 . VAL A 1 87 ? 50.390 31.591 54.928 1.00 28.53 ? 302 VAL A CG2 1 ATOM 542 N N . VAL A 1 88 ? 54.366 29.462 53.614 1.00 27.91 ? 303 VAL A N 1 ATOM 543 C CA . VAL A 1 88 ? 55.053 28.246 53.198 1.00 26.19 ? 303 VAL A CA 1 ATOM 544 C C . VAL A 1 88 ? 55.635 27.411 54.332 1.00 27.44 ? 303 VAL A C 1 ATOM 545 O O . VAL A 1 88 ? 56.163 27.926 55.302 1.00 28.82 ? 303 VAL A O 1 ATOM 546 C CB . VAL A 1 88 ? 56.168 28.562 52.203 1.00 23.98 ? 303 VAL A CB 1 ATOM 547 C CG1 . VAL A 1 88 ? 56.930 27.305 51.865 1.00 24.18 ? 303 VAL A CG1 1 ATOM 548 C CG2 . VAL A 1 88 ? 55.575 29.174 50.953 1.00 22.48 ? 303 VAL A CG2 1 ATOM 549 N N . SER A 1 89 ? 55.541 26.098 54.198 1.00 28.01 ? 304 SER A N 1 ATOM 550 C CA . SER A 1 89 ? 56.062 25.210 55.217 1.00 27.58 ? 304 SER A CA 1 ATOM 551 C C . SER A 1 89 ? 56.845 24.111 54.545 1.00 26.95 ? 304 SER A C 1 ATOM 552 O O . SER A 1 89 ? 56.351 23.492 53.627 1.00 30.20 ? 304 SER A O 1 ATOM 553 C CB . SER A 1 89 ? 54.924 24.609 56.003 1.00 26.18 ? 304 SER A CB 1 ATOM 554 O OG . SER A 1 89 ? 55.460 23.941 57.113 1.00 32.27 ? 304 SER A OG 1 ATOM 555 N N . VAL A 1 90 ? 58.064 23.857 54.984 1.00 25.56 ? 305 VAL A N 1 ATOM 556 C CA . VAL A 1 90 ? 58.837 22.829 54.326 1.00 25.45 ? 305 VAL A CA 1 ATOM 557 C C . VAL A 1 90 ? 59.251 21.718 55.263 1.00 28.52 ? 305 VAL A C 1 ATOM 558 O O . VAL A 1 90 ? 59.460 21.930 56.466 1.00 29.45 ? 305 VAL A O 1 ATOM 559 C CB . VAL A 1 90 ? 60.080 23.421 53.671 1.00 23.44 ? 305 VAL A CB 1 ATOM 560 C CG1 . VAL A 1 90 ? 59.776 24.780 53.184 1.00 25.68 ? 305 VAL A CG1 1 ATOM 561 C CG2 . VAL A 1 90 ? 61.212 23.477 54.636 1.00 26.74 ? 305 VAL A CG2 1 ATOM 562 N N . LEU A 1 91 ? 59.382 20.529 54.691 1.00 28.98 ? 306 LEU A N 1 ATOM 563 C CA . LEU A 1 91 ? 59.752 19.355 55.446 1.00 30.48 ? 306 LEU A CA 1 ATOM 564 C C . LEU A 1 91 ? 60.955 18.664 54.803 1.00 32.26 ? 306 LEU A C 1 ATOM 565 O O . LEU A 1 91 ? 60.858 18.174 53.682 1.00 34.13 ? 306 LEU A O 1 ATOM 566 C CB . LEU A 1 91 ? 58.565 18.400 55.475 1.00 28.37 ? 306 LEU A CB 1 ATOM 567 C CG . LEU A 1 91 ? 58.385 17.577 56.742 1.00 31.47 ? 306 LEU A CG 1 ATOM 568 C CD1 . LEU A 1 91 ? 57.533 16.364 56.431 1.00 34.10 ? 306 LEU A CD1 1 ATOM 569 C CD2 . LEU A 1 91 ? 59.715 17.136 57.275 1.00 31.48 ? 306 LEU A CD2 1 ATOM 570 N N . THR A 1 92 ? 62.100 18.632 55.469 1.00 31.91 ? 307 THR A N 1 ATOM 571 C CA . THR A 1 92 ? 63.203 17.926 54.846 1.00 34.08 ? 307 THR A CA 1 ATOM 572 C C . THR A 1 92 ? 62.770 16.471 54.867 1.00 35.84 ? 307 THR A C 1 ATOM 573 O O . THR A 1 92 ? 62.067 16.050 55.790 1.00 37.19 ? 307 THR A O 1 ATOM 574 C CB . THR A 1 92 ? 64.508 18.059 55.645 1.00 36.09 ? 307 THR A CB 1 ATOM 575 O OG1 . THR A 1 92 ? 65.206 19.234 55.226 1.00 39.37 ? 307 THR A OG1 1 ATOM 576 C CG2 . THR A 1 92 ? 65.414 16.836 55.423 1.00 36.79 ? 307 THR A CG2 1 ATOM 577 N N . VAL A 1 93 ? 63.155 15.702 53.855 1.00 34.56 ? 308 VAL A N 1 ATOM 578 C CA . VAL A 1 93 ? 62.803 14.290 53.843 1.00 33.80 ? 308 VAL A CA 1 ATOM 579 C C . VAL A 1 93 ? 64.075 13.485 53.688 1.00 34.46 ? 308 VAL A C 1 ATOM 580 O O . VAL A 1 93 ? 65.040 13.947 53.080 1.00 34.55 ? 308 VAL A O 1 ATOM 581 C CB . VAL A 1 93 ? 61.831 13.932 52.697 1.00 34.51 ? 308 VAL A CB 1 ATOM 582 C CG1 . VAL A 1 93 ? 60.490 14.634 52.907 1.00 34.15 ? 308 VAL A CG1 1 ATOM 583 C CG2 . VAL A 1 93 ? 62.443 14.297 51.356 1.00 34.08 ? 308 VAL A CG2 1 ATOM 584 N N . LEU A 1 94 ? 64.087 12.283 54.254 1.00 35.17 ? 309 LEU A N 1 ATOM 585 C CA . LEU A 1 94 ? 65.267 11.431 54.165 1.00 34.37 ? 309 LEU A CA 1 ATOM 586 C C . LEU A 1 94 ? 65.411 10.767 52.809 1.00 35.14 ? 309 LEU A C 1 ATOM 587 O O . LEU A 1 94 ? 64.474 10.161 52.286 1.00 36.05 ? 309 LEU A O 1 ATOM 588 C CB . LEU A 1 94 ? 65.234 10.351 55.240 1.00 31.92 ? 309 LEU A CB 1 ATOM 589 C CG . LEU A 1 94 ? 65.727 10.704 56.642 1.00 29.10 ? 309 LEU A CG 1 ATOM 590 C CD1 . LEU A 1 94 ? 65.260 12.079 57.028 1.00 25.42 ? 309 LEU A CD1 1 ATOM 591 C CD2 . LEU A 1 94 ? 65.226 9.638 57.637 1.00 26.35 ? 309 LEU A CD2 1 ATOM 592 N N . HIS A 1 95 ? 66.598 10.891 52.244 1.00 35.07 ? 310 HIS A N 1 ATOM 593 C CA . HIS A 1 95 ? 66.887 10.292 50.966 1.00 36.32 ? 310 HIS A CA 1 ATOM 594 C C . HIS A 1 95 ? 66.129 8.982 50.818 1.00 37.47 ? 310 HIS A C 1 ATOM 595 O O . HIS A 1 95 ? 65.485 8.734 49.800 1.00 39.42 ? 310 HIS A O 1 ATOM 596 C CB . HIS A 1 95 ? 68.374 10.016 50.865 1.00 37.47 ? 310 HIS A CB 1 ATOM 597 C CG . HIS A 1 95 ? 68.747 9.182 49.690 1.00 41.27 ? 310 HIS A CG 1 ATOM 598 N ND1 . HIS A 1 95 ? 69.103 9.726 48.476 1.00 43.81 ? 310 HIS A ND1 1 ATOM 599 C CD2 . HIS A 1 95 ? 68.788 7.840 49.529 1.00 43.28 ? 310 HIS A CD2 1 ATOM 600 C CE1 . HIS A 1 95 ? 69.352 8.752 47.618 1.00 45.08 ? 310 HIS A CE1 1 ATOM 601 N NE2 . HIS A 1 95 ? 69.167 7.598 48.231 1.00 44.54 ? 310 HIS A NE2 1 ATOM 602 N N . GLN A 1 96 ? 66.192 8.151 51.854 1.00 37.28 ? 311 GLN A N 1 ATOM 603 C CA . GLN A 1 96 ? 65.536 6.855 51.823 1.00 36.01 ? 311 GLN A CA 1 ATOM 604 C C . GLN A 1 96 ? 64.034 6.830 52.070 1.00 36.12 ? 311 GLN A C 1 ATOM 605 O O . GLN A 1 96 ? 63.354 5.940 51.575 1.00 36.40 ? 311 GLN A O 1 ATOM 606 C CB . GLN A 1 96 ? 66.238 5.892 52.775 1.00 33.09 ? 311 GLN A CB 1 ATOM 607 C CG . GLN A 1 96 ? 66.959 6.562 53.887 1.00 36.83 ? 311 GLN A CG 1 ATOM 608 C CD . GLN A 1 96 ? 68.231 7.246 53.438 1.00 39.58 ? 311 GLN A CD 1 ATOM 609 O OE1 . GLN A 1 96 ? 69.259 6.611 53.212 1.00 39.76 ? 311 GLN A OE1 1 ATOM 610 N NE2 . GLN A 1 96 ? 68.164 8.557 53.302 1.00 43.98 ? 311 GLN A NE2 1 ATOM 611 N N . ASP A 1 97 ? 63.495 7.784 52.815 1.00 36.81 ? 312 ASP A N 1 ATOM 612 C CA . ASP A 1 97 ? 62.054 7.761 53.046 1.00 36.93 ? 312 ASP A CA 1 ATOM 613 C C . ASP A 1 97 ? 61.302 8.042 51.761 1.00 34.93 ? 312 ASP A C 1 ATOM 614 O O . ASP A 1 97 ? 60.318 7.381 51.465 1.00 35.19 ? 312 ASP A O 1 ATOM 615 C CB . ASP A 1 97 ? 61.616 8.793 54.091 1.00 41.81 ? 312 ASP A CB 1 ATOM 616 C CG . ASP A 1 97 ? 62.059 8.440 55.505 1.00 46.16 ? 312 ASP A CG 1 ATOM 617 O OD1 . ASP A 1 97 ? 62.120 7.235 55.834 1.00 46.90 ? 312 ASP A OD1 1 ATOM 618 O OD2 . ASP A 1 97 ? 62.324 9.378 56.294 1.00 47.37 ? 312 ASP A OD2 1 ATOM 619 N N . TRP A 1 98 ? 61.763 9.021 50.992 1.00 33.24 ? 313 TRP A N 1 ATOM 620 C CA . TRP A 1 98 ? 61.072 9.375 49.757 1.00 31.54 ? 313 TRP A CA 1 ATOM 621 C C . TRP A 1 98 ? 61.157 8.284 48.694 1.00 32.65 ? 313 TRP A C 1 ATOM 622 O O . TRP A 1 98 ? 60.143 7.893 48.109 1.00 32.85 ? 313 TRP A O 1 ATOM 623 C CB . TRP A 1 98 ? 61.615 10.693 49.205 1.00 28.27 ? 313 TRP A CB 1 ATOM 624 C CG . TRP A 1 98 ? 61.006 11.083 47.897 1.00 25.84 ? 313 TRP A CG 1 ATOM 625 C CD1 . TRP A 1 98 ? 61.505 10.838 46.662 1.00 26.68 ? 313 TRP A CD1 1 ATOM 626 C CD2 . TRP A 1 98 ? 59.737 11.702 47.699 1.00 25.37 ? 313 TRP A CD2 1 ATOM 627 N NE1 . TRP A 1 98 ? 60.621 11.255 45.699 1.00 25.88 ? 313 TRP A NE1 1 ATOM 628 C CE2 . TRP A 1 98 ? 59.525 11.786 46.313 1.00 23.82 ? 313 TRP A CE2 1 ATOM 629 C CE3 . TRP A 1 98 ? 58.750 12.188 48.565 1.00 26.97 ? 313 TRP A CE3 1 ATOM 630 C CZ2 . TRP A 1 98 ? 58.374 12.335 45.766 1.00 26.45 ? 313 TRP A CZ2 1 ATOM 631 C CZ3 . TRP A 1 98 ? 57.604 12.733 48.028 1.00 27.18 ? 313 TRP A CZ3 1 ATOM 632 C CH2 . TRP A 1 98 ? 57.423 12.802 46.635 1.00 29.67 ? 313 TRP A CH2 1 ATOM 633 N N . LEU A 1 99 ? 62.365 7.792 48.447 1.00 31.92 ? 314 LEU A N 1 ATOM 634 C CA . LEU A 1 99 ? 62.567 6.746 47.462 1.00 29.68 ? 314 LEU A CA 1 ATOM 635 C C . LEU A 1 99 ? 61.932 5.412 47.851 1.00 30.38 ? 314 LEU A C 1 ATOM 636 O O . LEU A 1 99 ? 61.851 4.510 47.027 1.00 32.35 ? 314 LEU A O 1 ATOM 637 C CB . LEU A 1 99 ? 64.057 6.544 47.218 1.00 27.35 ? 314 LEU A CB 1 ATOM 638 C CG . LEU A 1 99 ? 64.777 7.733 46.595 1.00 26.65 ? 314 LEU A CG 1 ATOM 639 C CD1 . LEU A 1 99 ? 66.195 7.350 46.293 1.00 28.49 ? 314 LEU A CD1 1 ATOM 640 C CD2 . LEU A 1 99 ? 64.094 8.149 45.328 1.00 25.50 ? 314 LEU A CD2 1 ATOM 641 N N . ASN A 1 100 ? 61.505 5.265 49.102 1.00 29.93 ? 315 ASN A N 1 ATOM 642 C CA . ASN A 1 100 ? 60.875 4.020 49.530 1.00 28.64 ? 315 ASN A CA 1 ATOM 643 C C . ASN A 1 100 ? 59.398 4.250 49.530 1.00 28.98 ? 315 ASN A C 1 ATOM 644 O O . ASN A 1 100 ? 58.649 3.505 50.133 1.00 31.75 ? 315 ASN A O 1 ATOM 645 C CB . ASN A 1 100 ? 61.316 3.605 50.928 1.00 28.46 ? 315 ASN A CB 1 ATOM 646 C CG . ASN A 1 100 ? 62.639 2.891 50.926 1.00 30.56 ? 315 ASN A CG 1 ATOM 647 O OD1 . ASN A 1 100 ? 63.238 2.658 51.970 1.00 30.76 ? 315 ASN A OD1 1 ATOM 648 N ND2 . ASN A 1 100 ? 63.107 2.534 49.743 1.00 35.20 ? 315 ASN A ND2 1 ATOM 649 N N . GLY A 1 101 ? 58.982 5.313 48.868 1.00 27.93 ? 316 GLY A N 1 ATOM 650 C CA . GLY A 1 101 ? 57.570 5.598 48.780 1.00 27.99 ? 316 GLY A CA 1 ATOM 651 C C . GLY A 1 101 ? 56.822 6.065 50.001 1.00 27.86 ? 316 GLY A C 1 ATOM 652 O O . GLY A 1 101 ? 55.614 5.942 50.015 1.00 28.32 ? 316 GLY A O 1 ATOM 653 N N . LYS A 1 102 ? 57.501 6.599 51.010 1.00 30.63 ? 317 LYS A N 1 ATOM 654 C CA . LYS A 1 102 ? 56.809 7.087 52.207 1.00 34.51 ? 317 LYS A CA 1 ATOM 655 C C . LYS A 1 102 ? 55.815 8.172 51.801 1.00 37.69 ? 317 LYS A C 1 ATOM 656 O O . LYS A 1 102 ? 56.069 8.915 50.862 1.00 38.13 ? 317 LYS A O 1 ATOM 657 C CB . LYS A 1 102 ? 57.799 7.690 53.207 1.00 35.90 ? 317 LYS A CB 1 ATOM 658 C CG . LYS A 1 102 ? 57.929 6.949 54.535 1.00 36.09 ? 317 LYS A CG 1 ATOM 659 C CD . LYS A 1 102 ? 58.842 5.746 54.409 1.00 37.50 ? 317 LYS A CD 1 ATOM 660 C CE . LYS A 1 102 ? 58.908 4.942 55.702 1.00 38.04 ? 317 LYS A CE 1 ATOM 661 N NZ . LYS A 1 102 ? 59.481 5.702 56.843 1.00 36.20 ? 317 LYS A NZ 1 ATOM 662 N N . GLU A 1 103 ? 54.681 8.260 52.492 1.00 40.88 ? 318 GLU A N 1 ATOM 663 C CA . GLU A 1 103 ? 53.696 9.288 52.176 1.00 43.21 ? 318 GLU A CA 1 ATOM 664 C C . GLU A 1 103 ? 53.789 10.471 53.134 1.00 44.44 ? 318 GLU A C 1 ATOM 665 O O . GLU A 1 103 ? 53.858 10.299 54.357 1.00 45.09 ? 318 GLU A O 1 ATOM 666 C CB . GLU A 1 103 ? 52.293 8.732 52.246 1.00 45.30 ? 318 GLU A CB 1 ATOM 667 C CG . GLU A 1 103 ? 52.027 7.649 51.263 1.00 53.33 ? 318 GLU A CG 1 ATOM 668 C CD . GLU A 1 103 ? 50.545 7.493 51.015 1.00 58.02 ? 318 GLU A CD 1 ATOM 669 O OE1 . GLU A 1 103 ? 50.146 6.513 50.326 1.00 60.29 ? 318 GLU A OE1 1 ATOM 670 O OE2 . GLU A 1 103 ? 49.789 8.367 51.510 1.00 57.14 ? 318 GLU A OE2 1 ATOM 671 N N . TYR A 1 104 ? 53.775 11.676 52.571 1.00 43.24 ? 319 TYR A N 1 ATOM 672 C CA . TYR A 1 104 ? 53.856 12.887 53.364 1.00 40.85 ? 319 TYR A CA 1 ATOM 673 C C . TYR A 1 104 ? 52.549 13.653 53.312 1.00 42.76 ? 319 TYR A C 1 ATOM 674 O O . TYR A 1 104 ? 52.070 14.024 52.234 1.00 44.92 ? 319 TYR A O 1 ATOM 675 C CB . TYR A 1 104 ? 54.991 13.752 52.849 1.00 38.07 ? 319 TYR A CB 1 ATOM 676 C CG . TYR A 1 104 ? 56.318 13.080 52.980 1.00 34.36 ? 319 TYR A CG 1 ATOM 677 C CD1 . TYR A 1 104 ? 56.776 12.215 52.019 1.00 34.31 ? 319 TYR A CD1 1 ATOM 678 C CD2 . TYR A 1 104 ? 57.081 13.257 54.111 1.00 36.39 ? 319 TYR A CD2 1 ATOM 679 C CE1 . TYR A 1 104 ? 57.964 11.537 52.187 1.00 35.97 ? 319 TYR A CE1 1 ATOM 680 C CE2 . TYR A 1 104 ? 58.258 12.588 54.290 1.00 35.99 ? 319 TYR A CE2 1 ATOM 681 C CZ . TYR A 1 104 ? 58.696 11.730 53.329 1.00 35.80 ? 319 TYR A CZ 1 ATOM 682 O OH . TYR A 1 104 ? 59.873 11.059 53.536 1.00 40.13 ? 319 TYR A OH 1 ATOM 683 N N . LYS A 1 105 ? 51.962 13.868 54.485 1.00 43.51 ? 320 LYS A N 1 ATOM 684 C CA . LYS A 1 105 ? 50.703 14.594 54.593 1.00 44.22 ? 320 LYS A CA 1 ATOM 685 C C . LYS A 1 105 ? 50.904 15.878 55.367 1.00 45.50 ? 320 LYS A C 1 ATOM 686 O O . LYS A 1 105 ? 51.529 15.902 56.428 1.00 46.05 ? 320 LYS A O 1 ATOM 687 C CB . LYS A 1 105 ? 49.632 13.755 55.293 1.00 44.57 ? 320 LYS A CB 1 ATOM 688 C CG . LYS A 1 105 ? 48.451 14.577 55.800 1.00 44.89 ? 320 LYS A CG 1 ATOM 689 C CD . LYS A 1 105 ? 47.112 13.999 55.361 1.00 45.51 ? 320 LYS A CD 1 ATOM 690 C CE . LYS A 1 105 ? 46.810 12.690 56.052 1.00 45.34 ? 320 LYS A CE 1 ATOM 691 N NZ . LYS A 1 105 ? 46.624 12.884 57.506 1.00 45.26 ? 320 LYS A NZ 1 ATOM 692 N N . CYS A 1 106 ? 50.363 16.947 54.807 1.00 46.01 ? 321 CYS A N 1 ATOM 693 C CA . CYS A 1 106 ? 50.439 18.268 55.385 1.00 45.19 ? 321 CYS A CA 1 ATOM 694 C C . CYS A 1 106 ? 49.006 18.669 55.756 1.00 46.15 ? 321 CYS A C 1 ATOM 695 O O . CYS A 1 106 ? 48.132 18.723 54.894 1.00 46.44 ? 321 CYS A O 1 ATOM 696 C CB . CYS A 1 106 ? 51.030 19.228 54.353 1.00 43.55 ? 321 CYS A CB 1 ATOM 697 S SG . CYS A 1 106 ? 50.848 20.968 54.819 1.00 49.96 ? 321 CYS A SG 1 ATOM 698 N N . LYS A 1 107 ? 48.761 18.914 57.041 1.00 46.16 ? 322 LYS A N 1 ATOM 699 C CA . LYS A 1 107 ? 47.441 19.316 57.508 1.00 46.57 ? 322 LYS A CA 1 ATOM 700 C C . LYS A 1 107 ? 47.469 20.826 57.734 1.00 47.83 ? 322 LYS A C 1 ATOM 701 O O . LYS A 1 107 ? 48.345 21.338 58.433 1.00 49.45 ? 322 LYS A O 1 ATOM 702 C CB . LYS A 1 107 ? 47.100 18.590 58.808 1.00 47.09 ? 322 LYS A CB 1 ATOM 703 C CG . LYS A 1 107 ? 45.692 18.839 59.308 1.00 49.16 ? 322 LYS A CG 1 ATOM 704 C CD . LYS A 1 107 ? 45.381 18.001 60.531 1.00 50.31 ? 322 LYS A CD 1 ATOM 705 C CE . LYS A 1 107 ? 43.939 18.225 60.988 1.00 52.22 ? 322 LYS A CE 1 ATOM 706 N NZ . LYS A 1 107 ? 43.626 17.584 62.310 1.00 52.30 ? 322 LYS A NZ 1 ATOM 707 N N . VAL A 1 108 ? 46.509 21.535 57.148 1.00 46.67 ? 323 VAL A N 1 ATOM 708 C CA . VAL A 1 108 ? 46.459 22.992 57.256 1.00 44.90 ? 323 VAL A CA 1 ATOM 709 C C . VAL A 1 108 ? 45.231 23.521 57.974 1.00 45.29 ? 323 VAL A C 1 ATOM 710 O O . VAL A 1 108 ? 44.100 23.194 57.630 1.00 45.62 ? 323 VAL A O 1 ATOM 711 C CB . VAL A 1 108 ? 46.531 23.630 55.859 1.00 42.01 ? 323 VAL A CB 1 ATOM 712 C CG1 . VAL A 1 108 ? 46.472 25.120 55.956 1.00 41.82 ? 323 VAL A CG1 1 ATOM 713 C CG2 . VAL A 1 108 ? 47.810 23.214 55.189 1.00 42.33 ? 323 VAL A CG2 1 ATOM 714 N N . SER A 1 109 ? 45.460 24.360 58.972 1.00 45.68 ? 324 SER A N 1 ATOM 715 C CA . SER A 1 109 ? 44.361 24.922 59.734 1.00 46.12 ? 324 SER A CA 1 ATOM 716 C C . SER A 1 109 ? 44.469 26.434 59.860 1.00 46.46 ? 324 SER A C 1 ATOM 717 O O . SER A 1 109 ? 45.521 26.974 60.188 1.00 46.75 ? 324 SER A O 1 ATOM 718 C CB . SER A 1 109 ? 44.316 24.268 61.107 1.00 46.61 ? 324 SER A CB 1 ATOM 719 O OG . SER A 1 109 ? 45.588 23.729 61.420 1.00 52.16 ? 324 SER A OG 1 ATOM 720 N N . ASN A 1 110 ? 43.355 27.102 59.587 1.00 46.61 ? 325 ASN A N 1 ATOM 721 C CA . ASN A 1 110 ? 43.255 28.550 59.639 1.00 45.87 ? 325 ASN A CA 1 ATOM 722 C C . ASN A 1 110 ? 41.784 28.899 59.904 1.00 46.33 ? 325 ASN A C 1 ATOM 723 O O . ASN A 1 110 ? 40.881 28.191 59.479 1.00 46.60 ? 325 ASN A O 1 ATOM 724 C CB . ASN A 1 110 ? 43.773 29.117 58.315 1.00 44.23 ? 325 ASN A CB 1 ATOM 725 C CG . ASN A 1 110 ? 43.237 30.492 58.006 1.00 45.77 ? 325 ASN A CG 1 ATOM 726 O OD1 . ASN A 1 110 ? 42.114 30.641 57.512 1.00 43.77 ? 325 ASN A OD1 1 ATOM 727 N ND2 . ASN A 1 110 ? 44.038 31.510 58.288 1.00 44.73 ? 325 ASN A ND2 1 ATOM 728 N N . LYS A 1 111 ? 41.543 29.980 60.625 1.00 47.06 ? 326 LYS A N 1 ATOM 729 C CA . LYS A 1 111 ? 40.183 30.361 60.973 1.00 49.75 ? 326 LYS A CA 1 ATOM 730 C C . LYS A 1 111 ? 39.172 30.405 59.823 1.00 50.55 ? 326 LYS A C 1 ATOM 731 O O . LYS A 1 111 ? 38.012 30.051 60.016 1.00 51.12 ? 326 LYS A O 1 ATOM 732 C CB . LYS A 1 111 ? 40.203 31.709 61.710 1.00 51.64 ? 326 LYS A CB 1 ATOM 733 C CG . LYS A 1 111 ? 38.928 32.069 62.466 1.00 53.83 ? 326 LYS A CG 1 ATOM 734 C CD . LYS A 1 111 ? 37.865 32.666 61.554 1.00 58.85 ? 326 LYS A CD 1 ATOM 735 C CE . LYS A 1 111 ? 36.686 33.206 62.365 1.00 60.78 ? 326 LYS A CE 1 ATOM 736 N NZ . LYS A 1 111 ? 37.117 34.210 63.393 1.00 60.54 ? 326 LYS A NZ 1 ATOM 737 N N . ALA A 1 112 ? 39.595 30.835 58.638 1.00 51.51 ? 327 ALA A N 1 ATOM 738 C CA . ALA A 1 112 ? 38.676 30.933 57.504 1.00 52.10 ? 327 ALA A CA 1 ATOM 739 C C . ALA A 1 112 ? 38.487 29.590 56.824 1.00 53.78 ? 327 ALA A C 1 ATOM 740 O O . ALA A 1 112 ? 38.152 29.513 55.642 1.00 54.63 ? 327 ALA A O 1 ATOM 741 C CB . ALA A 1 112 ? 39.184 31.953 56.502 1.00 51.57 ? 327 ALA A CB 1 ATOM 742 N N . LEU A 1 113 ? 38.695 28.528 57.583 1.00 54.71 ? 328 LEU A N 1 ATOM 743 C CA . LEU A 1 113 ? 38.561 27.193 57.048 1.00 55.28 ? 328 LEU A CA 1 ATOM 744 C C . LEU A 1 113 ? 37.630 26.368 57.917 1.00 58.08 ? 328 LEU A C 1 ATOM 745 O O . LEU A 1 113 ? 37.981 26.000 59.038 1.00 59.33 ? 328 LEU A O 1 ATOM 746 C CB . LEU A 1 113 ? 39.934 26.530 56.983 1.00 52.42 ? 328 LEU A CB 1 ATOM 747 C CG . LEU A 1 113 ? 40.462 26.143 55.605 1.00 52.49 ? 328 LEU A CG 1 ATOM 748 C CD1 . LEU A 1 113 ? 40.068 27.194 54.599 1.00 54.17 ? 328 LEU A CD1 1 ATOM 749 C CD2 . LEU A 1 113 ? 41.979 25.982 55.653 1.00 51.71 ? 328 LEU A CD2 1 ATOM 750 N N . PRO A 1 114 ? 36.418 26.076 57.419 1.00 59.13 ? 329 PRO A N 1 ATOM 751 C CA . PRO A 1 114 ? 35.496 25.272 58.224 1.00 58.79 ? 329 PRO A CA 1 ATOM 752 C C . PRO A 1 114 ? 36.256 24.091 58.820 1.00 57.86 ? 329 PRO A C 1 ATOM 753 O O . PRO A 1 114 ? 36.320 23.924 60.043 1.00 58.22 ? 329 PRO A O 1 ATOM 754 C CB . PRO A 1 114 ? 34.440 24.843 57.208 1.00 59.71 ? 329 PRO A CB 1 ATOM 755 C CG . PRO A 1 114 ? 35.170 24.947 55.873 1.00 59.42 ? 329 PRO A CG 1 ATOM 756 C CD . PRO A 1 114 ? 35.922 26.218 56.040 1.00 58.48 ? 329 PRO A CD 1 ATOM 757 N N . ALA A 1 115 ? 36.849 23.285 57.950 1.00 55.38 ? 330 ALA A N 1 ATOM 758 C CA . ALA A 1 115 ? 37.625 22.143 58.410 1.00 55.27 ? 330 ALA A CA 1 ATOM 759 C C . ALA A 1 115 ? 39.039 22.171 57.804 1.00 53.88 ? 330 ALA A C 1 ATOM 760 O O . ALA A 1 115 ? 39.231 22.618 56.665 1.00 55.55 ? 330 ALA A O 1 ATOM 761 C CB . ALA A 1 115 ? 36.910 20.853 58.044 1.00 54.79 ? 330 ALA A CB 1 ATOM 762 N N . PRO A 1 116 ? 40.048 21.704 58.562 1.00 49.89 ? 331 PRO A N 1 ATOM 763 C CA . PRO A 1 116 ? 41.420 21.694 58.063 1.00 48.48 ? 331 PRO A CA 1 ATOM 764 C C . PRO A 1 116 ? 41.484 21.018 56.704 1.00 48.76 ? 331 PRO A C 1 ATOM 765 O O . PRO A 1 116 ? 40.652 20.163 56.400 1.00 48.93 ? 331 PRO A O 1 ATOM 766 C CB . PRO A 1 116 ? 42.159 20.901 59.128 1.00 47.27 ? 331 PRO A CB 1 ATOM 767 C CG . PRO A 1 116 ? 41.424 21.236 60.358 1.00 46.14 ? 331 PRO A CG 1 ATOM 768 C CD . PRO A 1 116 ? 39.993 21.128 59.912 1.00 48.32 ? 331 PRO A CD 1 ATOM 769 N N . ILE A 1 117 ? 42.466 21.417 55.893 1.00 48.20 ? 332 ILE A N 1 ATOM 770 C CA . ILE A 1 117 ? 42.683 20.854 54.560 1.00 46.03 ? 332 ILE A CA 1 ATOM 771 C C . ILE A 1 117 ? 43.917 19.951 54.551 1.00 46.51 ? 332 ILE A C 1 ATOM 772 O O . ILE A 1 117 ? 45.019 20.396 54.851 1.00 46.48 ? 332 ILE A O 1 ATOM 773 C CB . ILE A 1 117 ? 42.893 21.957 53.498 1.00 43.56 ? 332 ILE A CB 1 ATOM 774 C CG1 . ILE A 1 117 ? 41.599 22.738 53.303 1.00 43.59 ? 332 ILE A CG1 1 ATOM 775 C CG2 . ILE A 1 117 ? 43.358 21.338 52.181 1.00 41.79 ? 332 ILE A CG2 1 ATOM 776 C CD1 . ILE A 1 117 ? 41.611 23.697 52.114 1.00 43.67 ? 332 ILE A CD1 1 ATOM 777 N N . GLU A 1 118 ? 43.722 18.684 54.199 1.00 46.52 ? 333 GLU A N 1 ATOM 778 C CA . GLU A 1 118 ? 44.811 17.728 54.148 1.00 46.41 ? 333 GLU A CA 1 ATOM 779 C C . GLU A 1 118 ? 45.225 17.469 52.710 1.00 45.57 ? 333 GLU A C 1 ATOM 780 O O . GLU A 1 118 ? 44.383 17.473 51.820 1.00 45.37 ? 333 GLU A O 1 ATOM 781 C CB . GLU A 1 118 ? 44.384 16.415 54.793 1.00 49.73 ? 333 GLU A CB 1 ATOM 782 C CG . GLU A 1 118 ? 44.291 16.463 56.303 1.00 54.91 ? 333 GLU A CG 1 ATOM 783 C CD . GLU A 1 118 ? 43.970 15.103 56.918 1.00 59.37 ? 333 GLU A CD 1 ATOM 784 O OE1 . GLU A 1 118 ? 44.224 14.931 58.136 1.00 60.46 ? 333 GLU A OE1 1 ATOM 785 O OE2 . GLU A 1 118 ? 43.462 14.215 56.187 1.00 60.42 ? 333 GLU A OE2 1 ATOM 786 N N . LYS A 1 119 ? 46.520 17.240 52.496 1.00 43.56 ? 334 LYS A N 1 ATOM 787 C CA . LYS A 1 119 ? 47.064 16.963 51.169 1.00 41.42 ? 334 LYS A CA 1 ATOM 788 C C . LYS A 1 119 ? 48.143 15.900 51.281 1.00 42.49 ? 334 LYS A C 1 ATOM 789 O O . LYS A 1 119 ? 48.866 15.853 52.281 1.00 41.50 ? 334 LYS A O 1 ATOM 790 C CB . LYS A 1 119 ? 47.670 18.226 50.589 1.00 38.95 ? 334 LYS A CB 1 ATOM 791 C CG . LYS A 1 119 ? 46.657 19.268 50.255 1.00 39.72 ? 334 LYS A CG 1 ATOM 792 C CD . LYS A 1 119 ? 46.094 19.062 48.881 1.00 40.95 ? 334 LYS A CD 1 ATOM 793 C CE . LYS A 1 119 ? 45.114 20.163 48.542 1.00 44.46 ? 334 LYS A CE 1 ATOM 794 N NZ . LYS A 1 119 ? 44.937 20.351 47.067 1.00 46.20 ? 334 LYS A NZ 1 ATOM 795 N N . THR A 1 120 ? 48.267 15.047 50.265 1.00 43.16 ? 335 THR A N 1 ATOM 796 C CA . THR A 1 120 ? 49.290 14.003 50.315 1.00 44.53 ? 335 THR A CA 1 ATOM 797 C C . THR A 1 120 ? 50.127 13.825 49.043 1.00 44.84 ? 335 THR A C 1 ATOM 798 O O . THR A 1 120 ? 49.649 14.056 47.931 1.00 46.40 ? 335 THR A O 1 ATOM 799 C CB . THR A 1 120 ? 48.673 12.631 50.639 1.00 44.40 ? 335 THR A CB 1 ATOM 800 O OG1 . THR A 1 120 ? 47.714 12.749 51.695 1.00 45.73 ? 335 THR A OG1 1 ATOM 801 C CG2 . THR A 1 120 ? 49.758 11.685 51.106 1.00 47.90 ? 335 THR A CG2 1 ATOM 802 N N . ILE A 1 121 ? 51.385 13.427 49.211 1.00 43.58 ? 336 ILE A N 1 ATOM 803 C CA . ILE A 1 121 ? 52.250 13.158 48.062 1.00 43.82 ? 336 ILE A CA 1 ATOM 804 C C . ILE A 1 121 ? 53.236 12.075 48.424 1.00 43.46 ? 336 ILE A C 1 ATOM 805 O O . ILE A 1 121 ? 53.335 11.694 49.589 1.00 45.14 ? 336 ILE A O 1 ATOM 806 C CB . ILE A 1 121 ? 53.046 14.370 47.605 1.00 43.56 ? 336 ILE A CB 1 ATOM 807 C CG1 . ILE A 1 121 ? 53.922 14.870 48.739 1.00 44.83 ? 336 ILE A CG1 1 ATOM 808 C CG2 . ILE A 1 121 ? 52.105 15.442 47.115 1.00 45.85 ? 336 ILE A CG2 1 ATOM 809 C CD1 . ILE A 1 121 ? 54.780 16.023 48.337 1.00 49.15 ? 336 ILE A CD1 1 ATOM 810 N N . SER A 1 122 ? 53.970 11.591 47.427 1.00 41.84 ? 337 SER A N 1 ATOM 811 C CA . SER A 1 122 ? 54.945 10.524 47.627 1.00 40.94 ? 337 SER A CA 1 ATOM 812 C C . SER A 1 122 ? 55.339 10.021 46.257 1.00 39.80 ? 337 SER A C 1 ATOM 813 O O . SER A 1 122 ? 54.597 10.198 45.308 1.00 41.36 ? 337 SER A O 1 ATOM 814 C CB . SER A 1 122 ? 54.311 9.371 48.389 1.00 42.13 ? 337 SER A CB 1 ATOM 815 O OG . SER A 1 122 ? 53.226 8.846 47.639 1.00 42.78 ? 337 SER A OG 1 ATOM 816 N N . LYS A 1 123 ? 56.492 9.380 46.150 1.00 38.83 ? 338 LYS A N 1 ATOM 817 C CA . LYS A 1 123 ? 56.948 8.860 44.868 1.00 38.54 ? 338 LYS A CA 1 ATOM 818 C C . LYS A 1 123 ? 55.813 8.097 44.201 1.00 38.72 ? 338 LYS A C 1 ATOM 819 O O . LYS A 1 123 ? 54.938 7.568 44.882 1.00 38.90 ? 338 LYS A O 1 ATOM 820 C CB . LYS A 1 123 ? 58.135 7.924 45.085 1.00 39.01 ? 338 LYS A CB 1 ATOM 821 C CG . LYS A 1 123 ? 58.934 7.650 43.841 1.00 39.72 ? 338 LYS A CG 1 ATOM 822 C CD . LYS A 1 123 ? 60.142 6.791 44.148 1.00 40.21 ? 338 LYS A CD 1 ATOM 823 C CE . LYS A 1 123 ? 59.718 5.402 44.582 1.00 42.35 ? 338 LYS A CE 1 ATOM 824 N NZ . LYS A 1 123 ? 60.826 4.411 44.427 1.00 42.63 ? 338 LYS A NZ 1 ATOM 825 N N . ALA A 1 124 ? 55.806 8.043 42.874 1.00 38.25 ? 339 ALA A N 1 ATOM 826 C CA . ALA A 1 124 ? 54.754 7.295 42.189 1.00 37.27 ? 339 ALA A CA 1 ATOM 827 C C . ALA A 1 124 ? 54.881 5.836 42.584 1.00 37.90 ? 339 ALA A C 1 ATOM 828 O O . ALA A 1 124 ? 55.979 5.345 42.840 1.00 40.79 ? 339 ALA A O 1 ATOM 829 C CB . ALA A 1 124 ? 54.893 7.422 40.683 1.00 35.09 ? 339 ALA A CB 1 ATOM 830 N N . LYS A 1 125 ? 53.763 5.131 42.643 1.00 38.75 ? 340 LYS A N 1 ATOM 831 C CA . LYS A 1 125 ? 53.821 3.718 42.985 1.00 37.45 ? 340 LYS A CA 1 ATOM 832 C C . LYS A 1 125 ? 54.086 2.964 41.675 1.00 36.47 ? 340 LYS A C 1 ATOM 833 O O . LYS A 1 125 ? 53.932 3.530 40.593 1.00 35.09 ? 340 LYS A O 1 ATOM 834 C CB . LYS A 1 125 ? 52.505 3.289 43.643 1.00 37.59 ? 340 LYS A CB 1 ATOM 835 C CG . LYS A 1 125 ? 52.086 4.206 44.774 1.00 35.93 ? 340 LYS A CG 1 ATOM 836 C CD . LYS A 1 125 ? 51.315 3.479 45.849 1.00 38.37 ? 340 LYS A CD 1 ATOM 837 C CE . LYS A 1 125 ? 51.684 3.993 47.264 1.00 45.18 ? 340 LYS A CE 1 ATOM 838 N NZ . LYS A 1 125 ? 51.279 5.427 47.611 1.00 47.74 ? 340 LYS A NZ 1 ATOM 839 N N . GLY A 1 126 ? 54.500 1.706 41.768 1.00 36.19 ? 341 GLY A N 1 ATOM 840 C CA . GLY A 1 126 ? 54.797 0.939 40.572 1.00 34.85 ? 341 GLY A CA 1 ATOM 841 C C . GLY A 1 126 ? 56.288 0.684 40.512 1.00 35.43 ? 341 GLY A C 1 ATOM 842 O O . GLY A 1 126 ? 57.074 1.569 40.829 1.00 35.16 ? 341 GLY A O 1 ATOM 843 N N . GLN A 1 127 ? 56.665 -0.525 40.101 1.00 37.85 ? 342 GLN A N 1 ATOM 844 C CA . GLN A 1 127 ? 58.063 -0.978 39.993 1.00 38.51 ? 342 GLN A CA 1 ATOM 845 C C . GLN A 1 127 ? 58.925 -0.083 39.107 1.00 36.73 ? 342 GLN A C 1 ATOM 846 O O . GLN A 1 127 ? 58.536 0.290 37.990 1.00 35.62 ? 342 GLN A O 1 ATOM 847 C CB . GLN A 1 127 ? 58.099 -2.425 39.454 1.00 42.45 ? 342 GLN A CB 1 ATOM 848 C CG . GLN A 1 127 ? 59.482 -3.046 39.189 1.00 45.91 ? 342 GLN A CG 1 ATOM 849 C CD . GLN A 1 127 ? 60.149 -3.615 40.440 1.00 49.49 ? 342 GLN A CD 1 ATOM 850 O OE1 . GLN A 1 127 ? 60.901 -2.927 41.127 1.00 52.76 ? 342 GLN A OE1 1 ATOM 851 N NE2 . GLN A 1 127 ? 59.866 -4.877 40.739 1.00 51.23 ? 342 GLN A NE2 1 ATOM 852 N N . PRO A 1 128 ? 60.108 0.282 39.613 1.00 33.77 ? 343 PRO A N 1 ATOM 853 C CA . PRO A 1 128 ? 61.069 1.135 38.914 1.00 32.96 ? 343 PRO A CA 1 ATOM 854 C C . PRO A 1 128 ? 61.693 0.430 37.729 1.00 31.50 ? 343 PRO A C 1 ATOM 855 O O . PRO A 1 128 ? 61.790 -0.776 37.718 1.00 30.80 ? 343 PRO A O 1 ATOM 856 C CB . PRO A 1 128 ? 62.087 1.463 40.002 1.00 33.22 ? 343 PRO A CB 1 ATOM 857 C CG . PRO A 1 128 ? 61.244 1.470 41.249 1.00 32.29 ? 343 PRO A CG 1 ATOM 858 C CD . PRO A 1 128 ? 60.418 0.220 41.051 1.00 32.91 ? 343 PRO A CD 1 ATOM 859 N N . ARG A 1 129 ? 62.111 1.197 36.732 1.00 32.77 ? 344 ARG A N 1 ATOM 860 C CA . ARG A 1 129 ? 62.725 0.639 35.535 1.00 34.09 ? 344 ARG A CA 1 ATOM 861 C C . ARG A 1 129 ? 63.993 1.444 35.165 1.00 34.82 ? 344 ARG A C 1 ATOM 862 O O . ARG A 1 129 ? 63.962 2.674 35.113 1.00 37.73 ? 344 ARG A O 1 ATOM 863 C CB . ARG A 1 129 ? 61.723 0.688 34.371 1.00 35.56 ? 344 ARG A CB 1 ATOM 864 C CG . ARG A 1 129 ? 60.317 0.127 34.654 1.00 35.91 ? 344 ARG A CG 1 ATOM 865 C CD . ARG A 1 129 ? 59.966 -1.014 33.680 1.00 40.40 ? 344 ARG A CD 1 ATOM 866 N NE . ARG A 1 129 ? 58.952 -0.718 32.655 1.00 44.50 ? 344 ARG A NE 1 ATOM 867 C CZ . ARG A 1 129 ? 57.637 -0.639 32.878 1.00 47.88 ? 344 ARG A CZ 1 ATOM 868 N NH1 . ARG A 1 129 ? 57.145 -0.824 34.101 1.00 50.31 ? 344 ARG A NH1 1 ATOM 869 N NH2 . ARG A 1 129 ? 56.802 -0.397 31.870 1.00 46.08 ? 344 ARG A NH2 1 ATOM 870 N N . GLU A 1 130 ? 65.097 0.751 34.903 1.00 32.53 ? 345 GLU A N 1 ATOM 871 C CA . GLU A 1 130 ? 66.357 1.391 34.534 1.00 31.93 ? 345 GLU A CA 1 ATOM 872 C C . GLU A 1 130 ? 66.351 1.857 33.083 1.00 32.68 ? 345 GLU A C 1 ATOM 873 O O . GLU A 1 130 ? 66.276 1.042 32.167 1.00 33.80 ? 345 GLU A O 1 ATOM 874 C CB . GLU A 1 130 ? 67.505 0.408 34.739 1.00 33.11 ? 345 GLU A CB 1 ATOM 875 C CG . GLU A 1 130 ? 68.889 0.951 34.440 1.00 35.81 ? 345 GLU A CG 1 ATOM 876 C CD . GLU A 1 130 ? 69.991 0.007 34.898 1.00 37.86 ? 345 GLU A CD 1 ATOM 877 O OE1 . GLU A 1 130 ? 71.183 0.278 34.614 1.00 39.49 ? 345 GLU A OE1 1 ATOM 878 O OE2 . GLU A 1 130 ? 69.666 -1.007 35.551 1.00 37.70 ? 345 GLU A OE2 1 ATOM 879 N N . PRO A 1 131 ? 66.463 3.178 32.852 1.00 32.50 ? 346 PRO A N 1 ATOM 880 C CA . PRO A 1 131 ? 66.467 3.756 31.506 1.00 32.06 ? 346 PRO A CA 1 ATOM 881 C C . PRO A 1 131 ? 67.770 3.511 30.776 1.00 32.55 ? 346 PRO A C 1 ATOM 882 O O . PRO A 1 131 ? 68.794 3.220 31.397 1.00 33.40 ? 346 PRO A O 1 ATOM 883 C CB . PRO A 1 131 ? 66.271 5.237 31.777 1.00 33.38 ? 346 PRO A CB 1 ATOM 884 C CG . PRO A 1 131 ? 67.091 5.440 33.003 1.00 32.92 ? 346 PRO A CG 1 ATOM 885 C CD . PRO A 1 131 ? 66.704 4.229 33.859 1.00 33.46 ? 346 PRO A CD 1 ATOM 886 N N . GLN A 1 132 ? 67.725 3.625 29.455 1.00 32.37 ? 347 GLN A N 1 ATOM 887 C CA . GLN A 1 132 ? 68.917 3.463 28.639 1.00 33.11 ? 347 GLN A CA 1 ATOM 888 C C . GLN A 1 132 ? 69.217 4.853 28.135 1.00 33.52 ? 347 GLN A C 1 ATOM 889 O O . GLN A 1 132 ? 68.295 5.630 27.879 1.00 35.75 ? 347 GLN A O 1 ATOM 890 C CB . GLN A 1 132 ? 68.658 2.558 27.443 1.00 35.48 ? 347 GLN A CB 1 ATOM 891 C CG . GLN A 1 132 ? 68.440 1.096 27.773 1.00 40.16 ? 347 GLN A CG 1 ATOM 892 C CD . GLN A 1 132 ? 67.043 0.624 27.404 1.00 42.84 ? 347 GLN A CD 1 ATOM 893 O OE1 . GLN A 1 132 ? 66.207 0.379 28.287 1.00 42.37 ? 347 GLN A OE1 1 ATOM 894 N NE2 . GLN A 1 132 ? 66.778 0.502 26.092 1.00 40.41 ? 347 GLN A NE2 1 ATOM 895 N N . VAL A 1 133 ? 70.494 5.184 28.002 1.00 30.66 ? 348 VAL A N 1 ATOM 896 C CA . VAL A 1 133 ? 70.845 6.501 27.516 1.00 28.67 ? 348 VAL A CA 1 ATOM 897 C C . VAL A 1 133 ? 71.564 6.381 26.197 1.00 30.17 ? 348 VAL A C 1 ATOM 898 O O . VAL A 1 133 ? 72.540 5.631 26.076 1.00 30.87 ? 348 VAL A O 1 ATOM 899 C CB . VAL A 1 133 ? 71.734 7.244 28.499 1.00 26.46 ? 348 VAL A CB 1 ATOM 900 C CG1 . VAL A 1 133 ? 71.900 8.676 28.052 1.00 27.61 ? 348 VAL A CG1 1 ATOM 901 C CG2 . VAL A 1 133 ? 71.114 7.214 29.859 1.00 24.66 ? 348 VAL A CG2 1 ATOM 902 N N . TYR A 1 134 ? 71.069 7.111 25.203 1.00 29.40 ? 349 TYR A N 1 ATOM 903 C CA . TYR A 1 134 ? 71.664 7.093 23.876 1.00 30.94 ? 349 TYR A CA 1 ATOM 904 C C . TYR A 1 134 ? 71.978 8.502 23.421 1.00 31.43 ? 349 TYR A C 1 ATOM 905 O O . TYR A 1 134 ? 71.161 9.409 23.551 1.00 34.58 ? 349 TYR A O 1 ATOM 906 C CB . TYR A 1 134 ? 70.715 6.437 22.888 1.00 31.08 ? 349 TYR A CB 1 ATOM 907 C CG . TYR A 1 134 ? 70.389 5.007 23.237 1.00 31.27 ? 349 TYR A CG 1 ATOM 908 C CD1 . TYR A 1 134 ? 71.366 4.018 23.170 1.00 30.00 ? 349 TYR A CD1 1 ATOM 909 C CD2 . TYR A 1 134 ? 69.098 4.640 23.626 1.00 29.08 ? 349 TYR A CD2 1 ATOM 910 C CE1 . TYR A 1 134 ? 71.064 2.693 23.476 1.00 30.14 ? 349 TYR A CE1 1 ATOM 911 C CE2 . TYR A 1 134 ? 68.789 3.320 23.932 1.00 29.15 ? 349 TYR A CE2 1 ATOM 912 C CZ . TYR A 1 134 ? 69.776 2.350 23.855 1.00 30.51 ? 349 TYR A CZ 1 ATOM 913 O OH . TYR A 1 134 ? 69.480 1.032 24.147 1.00 33.40 ? 349 TYR A OH 1 ATOM 914 N N . THR A 1 135 ? 73.176 8.685 22.893 1.00 30.34 ? 350 THR A N 1 ATOM 915 C CA . THR A 1 135 ? 73.611 9.991 22.422 1.00 29.25 ? 350 THR A CA 1 ATOM 916 C C . THR A 1 135 ? 73.572 9.866 20.922 1.00 29.07 ? 350 THR A C 1 ATOM 917 O O . THR A 1 135 ? 74.013 8.854 20.385 1.00 31.37 ? 350 THR A O 1 ATOM 918 C CB . THR A 1 135 ? 75.051 10.269 22.867 1.00 29.37 ? 350 THR A CB 1 ATOM 919 O OG1 . THR A 1 135 ? 75.856 9.134 22.534 1.00 28.76 ? 350 THR A OG1 1 ATOM 920 C CG2 . THR A 1 135 ? 75.124 10.518 24.368 1.00 26.75 ? 350 THR A CG2 1 ATOM 921 N N . LEU A 1 136 ? 73.058 10.872 20.230 1.00 27.31 ? 351 LEU A N 1 ATOM 922 C CA . LEU A 1 136 ? 72.975 10.763 18.785 1.00 27.66 ? 351 LEU A CA 1 ATOM 923 C C . LEU A 1 136 ? 73.481 12.007 18.109 1.00 28.16 ? 351 LEU A C 1 ATOM 924 O O . LEU A 1 136 ? 73.027 13.099 18.391 1.00 30.40 ? 351 LEU A O 1 ATOM 925 C CB . LEU A 1 136 ? 71.527 10.500 18.355 1.00 28.13 ? 351 LEU A CB 1 ATOM 926 C CG . LEU A 1 136 ? 70.708 9.474 19.160 1.00 27.82 ? 351 LEU A CG 1 ATOM 927 C CD1 . LEU A 1 136 ? 69.322 9.383 18.586 1.00 28.94 ? 351 LEU A CD1 1 ATOM 928 C CD2 . LEU A 1 136 ? 71.365 8.111 19.137 1.00 28.70 ? 351 LEU A CD2 1 ATOM 929 N N . PRO A 1 137 ? 74.440 11.854 17.199 1.00 28.61 ? 352 PRO A N 1 ATOM 930 C CA . PRO A 1 137 ? 75.048 12.948 16.438 1.00 29.97 ? 352 PRO A CA 1 ATOM 931 C C . PRO A 1 137 ? 74.056 13.778 15.616 1.00 32.29 ? 352 PRO A C 1 ATOM 932 O O . PRO A 1 137 ? 72.887 13.412 15.459 1.00 33.74 ? 352 PRO A O 1 ATOM 933 C CB . PRO A 1 137 ? 76.037 12.224 15.545 1.00 29.58 ? 352 PRO A CB 1 ATOM 934 C CG . PRO A 1 137 ? 75.426 10.857 15.391 1.00 26.28 ? 352 PRO A CG 1 ATOM 935 C CD . PRO A 1 137 ? 74.999 10.561 16.784 1.00 27.18 ? 352 PRO A CD 1 ATOM 936 N N . PRO A 1 138 ? 74.520 14.908 15.067 1.00 33.17 ? 353 PRO A N 1 ATOM 937 C CA . PRO A 1 138 ? 73.637 15.758 14.267 1.00 32.48 ? 353 PRO A CA 1 ATOM 938 C C . PRO A 1 138 ? 73.526 15.143 12.892 1.00 32.63 ? 353 PRO A C 1 ATOM 939 O O . PRO A 1 138 ? 74.393 14.371 12.494 1.00 31.67 ? 353 PRO A O 1 ATOM 940 C CB . PRO A 1 138 ? 74.376 17.101 14.212 1.00 32.65 ? 353 PRO A CB 1 ATOM 941 C CG . PRO A 1 138 ? 75.494 16.983 15.229 1.00 33.70 ? 353 PRO A CG 1 ATOM 942 C CD . PRO A 1 138 ? 75.849 15.521 15.208 1.00 33.31 ? 353 PRO A CD 1 ATOM 943 N N . SER A 1 139 ? 72.462 15.477 12.170 1.00 34.96 ? 354 SER A N 1 ATOM 944 C CA . SER A 1 139 ? 72.278 14.961 10.820 1.00 35.97 ? 354 SER A CA 1 ATOM 945 C C . SER A 1 139 ? 73.318 15.659 9.977 1.00 35.64 ? 354 SER A C 1 ATOM 946 O O . SER A 1 139 ? 73.583 16.845 10.159 1.00 36.43 ? 354 SER A O 1 ATOM 947 C CB . SER A 1 139 ? 70.888 15.297 10.283 1.00 37.18 ? 354 SER A CB 1 ATOM 948 O OG . SER A 1 139 ? 70.877 15.198 8.863 1.00 37.03 ? 354 SER A OG 1 ATOM 949 N N . ARG A 1 140 ? 73.913 14.938 9.049 1.00 35.85 ? 355 ARG A N 1 ATOM 950 C CA . ARG A 1 140 ? 74.924 15.561 8.239 1.00 38.12 ? 355 ARG A CA 1 ATOM 951 C C . ARG A 1 140 ? 74.471 16.900 7.667 1.00 38.51 ? 355 ARG A C 1 ATOM 952 O O . ARG A 1 140 ? 75.278 17.818 7.557 1.00 39.05 ? 355 ARG A O 1 ATOM 953 C CB . ARG A 1 140 ? 75.359 14.615 7.128 1.00 39.88 ? 355 ARG A CB 1 ATOM 954 C CG . ARG A 1 140 ? 76.426 15.176 6.196 1.00 44.75 ? 355 ARG A CG 1 ATOM 955 C CD . ARG A 1 140 ? 77.692 15.616 6.916 1.00 45.89 ? 355 ARG A CD 1 ATOM 956 N NE . ARG A 1 140 ? 78.732 15.982 5.958 1.00 49.64 ? 355 ARG A NE 1 ATOM 957 C CZ . ARG A 1 140 ? 79.371 15.111 5.177 1.00 51.79 ? 355 ARG A CZ 1 ATOM 958 N NH1 . ARG A 1 140 ? 79.084 13.820 5.247 1.00 52.82 ? 355 ARG A NH1 1 ATOM 959 N NH2 . ARG A 1 140 ? 80.287 15.525 4.309 1.00 52.31 ? 355 ARG A NH2 1 ATOM 960 N N . ASP A 1 141 ? 73.191 17.048 7.338 1.00 39.38 ? 356 ASP A N 1 ATOM 961 C CA . ASP A 1 141 ? 72.757 18.319 6.756 1.00 41.57 ? 356 ASP A CA 1 ATOM 962 C C . ASP A 1 141 ? 72.470 19.478 7.711 1.00 43.06 ? 356 ASP A C 1 ATOM 963 O O . ASP A 1 141 ? 72.000 20.533 7.291 1.00 44.39 ? 356 ASP A O 1 ATOM 964 C CB . ASP A 1 141 ? 71.566 18.130 5.796 1.00 40.67 ? 356 ASP A CB 1 ATOM 965 C CG . ASP A 1 141 ? 70.377 17.484 6.449 1.00 41.71 ? 356 ASP A CG 1 ATOM 966 O OD1 . ASP A 1 141 ? 70.218 17.631 7.673 1.00 43.17 ? 356 ASP A OD1 1 ATOM 967 O OD2 . ASP A 1 141 ? 69.588 16.840 5.733 1.00 41.78 ? 356 ASP A OD2 1 ATOM 968 N N . GLU A 1 142 ? 72.739 19.305 8.995 1.00 44.69 ? 357 GLU A N 1 ATOM 969 C CA . GLU A 1 142 ? 72.527 20.421 9.901 1.00 44.75 ? 357 GLU A CA 1 ATOM 970 C C . GLU A 1 142 ? 73.877 21.121 9.941 1.00 44.72 ? 357 GLU A C 1 ATOM 971 O O . GLU A 1 142 ? 74.000 22.245 10.410 1.00 43.87 ? 357 GLU A O 1 ATOM 972 C CB . GLU A 1 142 ? 72.110 19.945 11.300 1.00 45.53 ? 357 GLU A CB 1 ATOM 973 C CG . GLU A 1 142 ? 71.975 21.093 12.293 1.00 48.56 ? 357 GLU A CG 1 ATOM 974 C CD . GLU A 1 142 ? 71.141 20.762 13.526 1.00 50.82 ? 357 GLU A CD 1 ATOM 975 O OE1 . GLU A 1 142 ? 71.436 19.757 14.211 1.00 52.49 ? 357 GLU A OE1 1 ATOM 976 O OE2 . GLU A 1 142 ? 70.193 21.523 13.819 1.00 50.70 ? 357 GLU A OE2 1 ATOM 977 N N . LEU A 1 143 ? 74.888 20.439 9.411 1.00 45.44 ? 358 LEU A N 1 ATOM 978 C CA . LEU A 1 143 ? 76.246 20.960 9.370 1.00 45.94 ? 358 LEU A CA 1 ATOM 979 C C . LEU A 1 143 ? 76.460 22.112 8.380 1.00 47.05 ? 358 LEU A C 1 ATOM 980 O O . LEU A 1 143 ? 77.592 22.551 8.175 1.00 48.32 ? 358 LEU A O 1 ATOM 981 C CB . LEU A 1 143 ? 77.227 19.830 9.054 1.00 46.89 ? 358 LEU A CB 1 ATOM 982 C CG . LEU A 1 143 ? 77.898 19.043 10.188 1.00 47.45 ? 358 LEU A CG 1 ATOM 983 C CD1 . LEU A 1 143 ? 76.911 18.665 11.270 1.00 47.57 ? 358 LEU A CD1 1 ATOM 984 C CD2 . LEU A 1 143 ? 78.526 17.798 9.587 1.00 47.01 ? 358 LEU A CD2 1 ATOM 985 N N . THR A 1 144 ? 75.398 22.598 7.742 1.00 46.85 ? 359 THR A N 1 ATOM 986 C CA . THR A 1 144 ? 75.568 23.724 6.831 1.00 46.06 ? 359 THR A CA 1 ATOM 987 C C . THR A 1 144 ? 75.172 24.954 7.629 1.00 46.80 ? 359 THR A C 1 ATOM 988 O O . THR A 1 144 ? 75.285 26.089 7.157 1.00 48.83 ? 359 THR A O 1 ATOM 989 C CB . THR A 1 144 ? 74.680 23.620 5.574 1.00 45.65 ? 359 THR A CB 1 ATOM 990 O OG1 . THR A 1 144 ? 73.299 23.660 5.952 1.00 47.45 ? 359 THR A OG1 1 ATOM 991 C CG2 . THR A 1 144 ? 74.970 22.329 4.819 1.00 44.25 ? 359 THR A CG2 1 ATOM 992 N N . LYS A 1 145 ? 74.709 24.713 8.852 1.00 46.15 ? 360 LYS A N 1 ATOM 993 C CA . LYS A 1 145 ? 74.309 25.783 9.754 1.00 46.94 ? 360 LYS A CA 1 ATOM 994 C C . LYS A 1 145 ? 75.510 26.117 10.640 1.00 48.25 ? 360 LYS A C 1 ATOM 995 O O . LYS A 1 145 ? 76.545 25.450 10.557 1.00 47.77 ? 360 LYS A O 1 ATOM 996 C CB . LYS A 1 145 ? 73.129 25.334 10.611 1.00 46.76 ? 360 LYS A CB 1 ATOM 997 C CG . LYS A 1 145 ? 72.024 24.657 9.823 1.00 45.25 ? 360 LYS A CG 1 ATOM 998 C CD . LYS A 1 145 ? 70.826 25.546 9.661 1.00 45.67 ? 360 LYS A CD 1 ATOM 999 C CE . LYS A 1 145 ? 69.539 24.738 9.606 1.00 46.80 ? 360 LYS A CE 1 ATOM 1000 N NZ . LYS A 1 145 ? 69.517 23.768 8.478 1.00 50.00 ? 360 LYS A NZ 1 ATOM 1001 N N . ASN A 1 146 ? 75.369 27.138 11.485 1.00 49.16 ? 361 ASN A N 1 ATOM 1002 C CA . ASN A 1 146 ? 76.453 27.579 12.361 1.00 50.98 ? 361 ASN A CA 1 ATOM 1003 C C . ASN A 1 146 ? 76.415 26.901 13.730 1.00 50.56 ? 361 ASN A C 1 ATOM 1004 O O . ASN A 1 146 ? 77.389 26.940 14.480 1.00 51.67 ? 361 ASN A O 1 ATOM 1005 C CB . ASN A 1 146 ? 76.387 29.098 12.529 1.00 54.98 ? 361 ASN A CB 1 ATOM 1006 C CG . ASN A 1 146 ? 75.130 29.547 13.274 1.00 60.89 ? 361 ASN A CG 1 ATOM 1007 O OD1 . ASN A 1 146 ? 74.047 28.967 13.093 1.00 63.90 ? 361 ASN A OD1 1 ATOM 1008 N ND2 . ASN A 1 146 ? 75.264 30.586 14.109 1.00 60.73 ? 361 ASN A ND2 1 ATOM 1009 N N . GLN A 1 147 ? 75.283 26.292 14.058 1.00 49.16 ? 362 GLN A N 1 ATOM 1010 C CA . GLN A 1 147 ? 75.127 25.591 15.322 1.00 46.93 ? 362 GLN A CA 1 ATOM 1011 C C . GLN A 1 147 ? 74.578 24.197 15.018 1.00 45.93 ? 362 GLN A C 1 ATOM 1012 O O . GLN A 1 147 ? 73.731 24.035 14.132 1.00 46.45 ? 362 GLN A O 1 ATOM 1013 C CB . GLN A 1 147 ? 74.146 26.331 16.226 1.00 46.51 ? 362 GLN A CB 1 ATOM 1014 C CG . GLN A 1 147 ? 74.416 27.804 16.367 1.00 50.97 ? 362 GLN A CG 1 ATOM 1015 C CD . GLN A 1 147 ? 73.411 28.489 17.289 1.00 55.44 ? 362 GLN A CD 1 ATOM 1016 O OE1 . GLN A 1 147 ? 72.194 28.318 17.139 1.00 57.08 ? 362 GLN A OE1 1 ATOM 1017 N NE2 . GLN A 1 147 ? 73.913 29.271 18.246 1.00 55.22 ? 362 GLN A NE2 1 ATOM 1018 N N . VAL A 1 148 ? 75.068 23.192 15.738 1.00 43.00 ? 363 VAL A N 1 ATOM 1019 C CA . VAL A 1 148 ? 74.601 21.828 15.541 1.00 40.63 ? 363 VAL A CA 1 ATOM 1020 C C . VAL A 1 148 ? 73.860 21.355 16.781 1.00 40.44 ? 363 VAL A C 1 ATOM 1021 O O . VAL A 1 148 ? 74.032 21.901 17.872 1.00 39.43 ? 363 VAL A O 1 ATOM 1022 C CB . VAL A 1 148 ? 75.758 20.853 15.242 1.00 39.30 ? 363 VAL A CB 1 ATOM 1023 C CG1 . VAL A 1 148 ? 76.467 21.268 13.977 1.00 36.58 ? 363 VAL A CG1 1 ATOM 1024 C CG2 . VAL A 1 148 ? 76.711 20.815 16.401 1.00 38.62 ? 363 VAL A CG2 1 ATOM 1025 N N . SER A 1 149 ? 73.029 20.337 16.603 1.00 39.47 ? 364 SER A N 1 ATOM 1026 C CA . SER A 1 149 ? 72.239 19.809 17.694 1.00 38.39 ? 364 SER A CA 1 ATOM 1027 C C . SER A 1 149 ? 72.665 18.402 18.059 1.00 37.64 ? 364 SER A C 1 ATOM 1028 O O . SER A 1 149 ? 72.610 17.497 17.234 1.00 40.31 ? 364 SER A O 1 ATOM 1029 C CB . SER A 1 149 ? 70.761 19.806 17.307 1.00 39.58 ? 364 SER A CB 1 ATOM 1030 O OG . SER A 1 149 ? 70.337 21.090 16.882 1.00 44.31 ? 364 SER A OG 1 ATOM 1031 N N . LEU A 1 150 ? 73.108 18.220 19.295 1.00 35.45 ? 365 LEU A N 1 ATOM 1032 C CA . LEU A 1 150 ? 73.497 16.908 19.751 1.00 32.78 ? 365 LEU A CA 1 ATOM 1033 C C . LEU A 1 150 ? 72.272 16.418 20.486 1.00 34.11 ? 365 LEU A C 1 ATOM 1034 O O . LEU A 1 150 ? 71.580 17.199 21.137 1.00 35.93 ? 365 LEU A O 1 ATOM 1035 C CB . LEU A 1 150 ? 74.705 16.999 20.663 1.00 30.42 ? 365 LEU A CB 1 ATOM 1036 C CG . LEU A 1 150 ? 75.961 17.551 19.981 1.00 29.78 ? 365 LEU A CG 1 ATOM 1037 C CD1 . LEU A 1 150 ? 77.149 17.363 20.902 1.00 30.22 ? 365 LEU A CD1 1 ATOM 1038 C CD2 . LEU A 1 150 ? 76.223 16.836 18.678 1.00 28.79 ? 365 LEU A CD2 1 ATOM 1039 N N . THR A 1 151 ? 71.983 15.133 20.366 1.00 34.58 ? 366 THR A N 1 ATOM 1040 C CA . THR A 1 151 ? 70.793 14.584 20.987 1.00 35.75 ? 366 THR A CA 1 ATOM 1041 C C . THR A 1 151 ? 71.068 13.464 21.970 1.00 38.28 ? 366 THR A C 1 ATOM 1042 O O . THR A 1 151 ? 71.874 12.570 21.700 1.00 40.36 ? 366 THR A O 1 ATOM 1043 C CB . THR A 1 151 ? 69.809 14.063 19.912 1.00 34.07 ? 366 THR A CB 1 ATOM 1044 O OG1 . THR A 1 151 ? 69.072 15.161 19.355 1.00 29.42 ? 366 THR A OG1 1 ATOM 1045 C CG2 . THR A 1 151 ? 68.861 13.055 20.506 1.00 31.69 ? 366 THR A CG2 1 ATOM 1046 N N . CYS A 1 152 ? 70.387 13.523 23.111 1.00 38.30 ? 367 CYS A N 1 ATOM 1047 C CA . CYS A 1 152 ? 70.528 12.507 24.134 1.00 37.61 ? 367 CYS A CA 1 ATOM 1048 C C . CYS A 1 152 ? 69.152 11.916 24.375 1.00 37.04 ? 367 CYS A C 1 ATOM 1049 O O . CYS A 1 152 ? 68.215 12.635 24.754 1.00 38.60 ? 367 CYS A O 1 ATOM 1050 C CB . CYS A 1 152 ? 71.047 13.114 25.424 1.00 40.10 ? 367 CYS A CB 1 ATOM 1051 S SG . CYS A 1 152 ? 71.384 11.860 26.690 1.00 44.89 ? 367 CYS A SG 1 ATOM 1052 N N . LEU A 1 153 ? 69.036 10.612 24.139 1.00 32.60 ? 368 LEU A N 1 ATOM 1053 C CA . LEU A 1 153 ? 67.781 9.903 24.311 1.00 29.47 ? 368 LEU A CA 1 ATOM 1054 C C . LEU A 1 153 ? 67.790 9.040 25.557 1.00 30.63 ? 368 LEU A C 1 ATOM 1055 O O . LEU A 1 153 ? 68.606 8.124 25.669 1.00 34.94 ? 368 LEU A O 1 ATOM 1056 C CB . LEU A 1 153 ? 67.505 9.016 23.098 1.00 23.91 ? 368 LEU A CB 1 ATOM 1057 C CG . LEU A 1 153 ? 66.269 8.114 23.209 1.00 20.36 ? 368 LEU A CG 1 ATOM 1058 C CD1 . LEU A 1 153 ? 65.049 8.952 23.492 1.00 17.48 ? 368 LEU A CD1 1 ATOM 1059 C CD2 . LEU A 1 153 ? 66.082 7.322 21.946 1.00 14.32 ? 368 LEU A CD2 1 ATOM 1060 N N . VAL A 1 154 ? 66.873 9.317 26.479 1.00 28.61 ? 369 VAL A N 1 ATOM 1061 C CA . VAL A 1 154 ? 66.761 8.555 27.717 1.00 28.40 ? 369 VAL A CA 1 ATOM 1062 C C . VAL A 1 154 ? 65.480 7.752 27.648 1.00 29.36 ? 369 VAL A C 1 ATOM 1063 O O . VAL A 1 154 ? 64.403 8.314 27.760 1.00 30.69 ? 369 VAL A O 1 ATOM 1064 C CB . VAL A 1 154 ? 66.660 9.486 28.930 1.00 27.49 ? 369 VAL A CB 1 ATOM 1065 C CG1 . VAL A 1 154 ? 66.587 8.681 30.204 1.00 26.79 ? 369 VAL A CG1 1 ATOM 1066 C CG2 . VAL A 1 154 ? 67.834 10.411 28.957 1.00 29.14 ? 369 VAL A CG2 1 ATOM 1067 N N . LYS A 1 155 ? 65.573 6.442 27.463 1.00 30.73 ? 370 LYS A N 1 ATOM 1068 C CA . LYS A 1 155 ? 64.346 5.651 27.387 1.00 31.91 ? 370 LYS A CA 1 ATOM 1069 C C . LYS A 1 155 ? 64.244 4.471 28.347 1.00 31.71 ? 370 LYS A C 1 ATOM 1070 O O . LYS A 1 155 ? 65.242 3.881 28.772 1.00 30.25 ? 370 LYS A O 1 ATOM 1071 C CB . LYS A 1 155 ? 64.110 5.122 25.964 1.00 29.50 ? 370 LYS A CB 1 ATOM 1072 C CG . LYS A 1 155 ? 65.091 4.060 25.563 1.00 31.93 ? 370 LYS A CG 1 ATOM 1073 C CD . LYS A 1 155 ? 64.650 3.296 24.324 1.00 33.85 ? 370 LYS A CD 1 ATOM 1074 C CE . LYS A 1 155 ? 63.613 2.235 24.658 1.00 34.02 ? 370 LYS A CE 1 ATOM 1075 N NZ . LYS A 1 155 ? 63.322 1.330 23.503 1.00 31.55 ? 370 LYS A NZ 1 ATOM 1076 N N . GLY A 1 156 ? 62.998 4.154 28.675 1.00 30.75 ? 371 GLY A N 1 ATOM 1077 C CA . GLY A 1 156 ? 62.706 3.034 29.526 1.00 30.19 ? 371 GLY A CA 1 ATOM 1078 C C . GLY A 1 156 ? 62.807 3.281 30.995 1.00 30.17 ? 371 GLY A C 1 ATOM 1079 O O . GLY A 1 156 ? 63.101 2.351 31.744 1.00 32.43 ? 371 GLY A O 1 ATOM 1080 N N . PHE A 1 157 ? 62.573 4.506 31.437 1.00 28.66 ? 372 PHE A N 1 ATOM 1081 C CA . PHE A 1 157 ? 62.662 4.726 32.863 1.00 28.13 ? 372 PHE A CA 1 ATOM 1082 C C . PHE A 1 157 ? 61.332 4.866 33.568 1.00 30.13 ? 372 PHE A C 1 ATOM 1083 O O . PHE A 1 157 ? 60.305 5.220 32.971 1.00 32.13 ? 372 PHE A O 1 ATOM 1084 C CB . PHE A 1 157 ? 63.536 5.931 33.200 1.00 26.15 ? 372 PHE A CB 1 ATOM 1085 C CG . PHE A 1 157 ? 63.062 7.236 32.626 1.00 24.46 ? 372 PHE A CG 1 ATOM 1086 C CD1 . PHE A 1 157 ? 63.392 7.605 31.331 1.00 26.41 ? 372 PHE A CD1 1 ATOM 1087 C CD2 . PHE A 1 157 ? 62.355 8.133 33.406 1.00 22.54 ? 372 PHE A CD2 1 ATOM 1088 C CE1 . PHE A 1 157 ? 63.028 8.859 30.828 1.00 23.91 ? 372 PHE A CE1 1 ATOM 1089 C CE2 . PHE A 1 157 ? 61.993 9.372 32.911 1.00 21.88 ? 372 PHE A CE2 1 ATOM 1090 C CZ . PHE A 1 157 ? 62.332 9.734 31.620 1.00 21.71 ? 372 PHE A CZ 1 ATOM 1091 N N . TYR A 1 158 ? 61.367 4.564 34.859 1.00 29.10 ? 373 TYR A N 1 ATOM 1092 C CA . TYR A 1 158 ? 60.201 4.665 35.703 1.00 27.09 ? 373 TYR A CA 1 ATOM 1093 C C . TYR A 1 158 ? 60.666 4.576 37.133 1.00 27.54 ? 373 TYR A C 1 ATOM 1094 O O . TYR A 1 158 ? 61.516 3.755 37.446 1.00 29.42 ? 373 TYR A O 1 ATOM 1095 C CB . TYR A 1 158 ? 59.240 3.532 35.420 1.00 25.06 ? 373 TYR A CB 1 ATOM 1096 C CG . TYR A 1 158 ? 57.945 3.720 36.133 1.00 22.04 ? 373 TYR A CG 1 ATOM 1097 C CD1 . TYR A 1 158 ? 57.816 3.413 37.480 1.00 22.16 ? 373 TYR A CD1 1 ATOM 1098 C CD2 . TYR A 1 158 ? 56.864 4.267 35.474 1.00 21.15 ? 373 TYR A CD2 1 ATOM 1099 C CE1 . TYR A 1 158 ? 56.632 3.654 38.145 1.00 25.27 ? 373 TYR A CE1 1 ATOM 1100 C CE2 . TYR A 1 158 ? 55.684 4.516 36.119 1.00 22.04 ? 373 TYR A CE2 1 ATOM 1101 C CZ . TYR A 1 158 ? 55.559 4.211 37.449 1.00 24.96 ? 373 TYR A CZ 1 ATOM 1102 O OH . TYR A 1 158 ? 54.349 4.452 38.067 1.00 26.79 ? 373 TYR A OH 1 ATOM 1103 N N . PRO A 1 159 ? 60.099 5.397 38.025 1.00 26.58 ? 374 PRO A N 1 ATOM 1104 C CA . PRO A 1 159 ? 59.057 6.378 37.729 1.00 27.94 ? 374 PRO A CA 1 ATOM 1105 C C . PRO A 1 159 ? 59.595 7.538 36.916 1.00 29.89 ? 374 PRO A C 1 ATOM 1106 O O . PRO A 1 159 ? 60.790 7.586 36.618 1.00 30.28 ? 374 PRO A O 1 ATOM 1107 C CB . PRO A 1 159 ? 58.574 6.784 39.107 1.00 27.77 ? 374 PRO A CB 1 ATOM 1108 C CG . PRO A 1 159 ? 59.812 6.676 39.922 1.00 28.32 ? 374 PRO A CG 1 ATOM 1109 C CD . PRO A 1 159 ? 60.406 5.382 39.463 1.00 26.44 ? 374 PRO A CD 1 ATOM 1110 N N . SER A 1 160 ? 58.714 8.475 36.577 1.00 29.87 ? 375 SER A N 1 ATOM 1111 C CA . SER A 1 160 ? 59.074 9.621 35.752 1.00 30.58 ? 375 SER A CA 1 ATOM 1112 C C . SER A 1 160 ? 59.974 10.715 36.313 1.00 30.83 ? 375 SER A C 1 ATOM 1113 O O . SER A 1 160 ? 60.318 11.633 35.587 1.00 32.24 ? 375 SER A O 1 ATOM 1114 C CB . SER A 1 160 ? 57.807 10.283 35.229 1.00 32.55 ? 375 SER A CB 1 ATOM 1115 O OG . SER A 1 160 ? 57.255 11.147 36.199 1.00 34.81 ? 375 SER A OG 1 ATOM 1116 N N . ASP A 1 161 ? 60.337 10.670 37.588 1.00 33.18 ? 376 ASP A N 1 ATOM 1117 C CA . ASP A 1 161 ? 61.216 11.714 38.110 1.00 34.96 ? 376 ASP A CA 1 ATOM 1118 C C . ASP A 1 161 ? 62.604 11.492 37.552 1.00 33.38 ? 376 ASP A C 1 ATOM 1119 O O . ASP A 1 161 ? 63.198 10.428 37.734 1.00 33.23 ? 376 ASP A O 1 ATOM 1120 C CB . ASP A 1 161 ? 61.279 11.698 39.635 1.00 41.00 ? 376 ASP A CB 1 ATOM 1121 C CG . ASP A 1 161 ? 60.061 12.324 40.269 1.00 47.49 ? 376 ASP A CG 1 ATOM 1122 O OD1 . ASP A 1 161 ? 59.425 13.178 39.598 1.00 50.33 ? 376 ASP A OD1 1 ATOM 1123 O OD2 . ASP A 1 161 ? 59.754 11.979 41.437 1.00 50.98 ? 376 ASP A OD2 1 ATOM 1124 N N . ILE A 1 162 ? 63.131 12.502 36.877 1.00 30.88 ? 377 ILE A N 1 ATOM 1125 C CA . ILE A 1 162 ? 64.441 12.365 36.276 1.00 27.24 ? 377 ILE A CA 1 ATOM 1126 C C . ILE A 1 162 ? 65.088 13.733 36.159 1.00 26.53 ? 377 ILE A C 1 ATOM 1127 O O . ILE A 1 162 ? 64.415 14.745 36.214 1.00 26.75 ? 377 ILE A O 1 ATOM 1128 C CB . ILE A 1 162 ? 64.298 11.712 34.884 1.00 24.83 ? 377 ILE A CB 1 ATOM 1129 C CG1 . ILE A 1 162 ? 65.588 11.011 34.492 1.00 23.59 ? 377 ILE A CG1 1 ATOM 1130 C CG2 . ILE A 1 162 ? 63.941 12.756 33.854 1.00 21.87 ? 377 ILE A CG2 1 ATOM 1131 C CD1 . ILE A 1 162 ? 65.512 10.375 33.146 1.00 23.46 ? 377 ILE A CD1 1 ATOM 1132 N N . ALA A 1 163 ? 66.401 13.761 36.016 1.00 25.99 ? 378 ALA A N 1 ATOM 1133 C CA . ALA A 1 163 ? 67.111 15.017 35.883 1.00 26.80 ? 378 ALA A CA 1 ATOM 1134 C C . ALA A 1 163 ? 68.062 14.806 34.736 1.00 28.07 ? 378 ALA A C 1 ATOM 1135 O O . ALA A 1 163 ? 68.526 13.689 34.545 1.00 30.19 ? 378 ALA A O 1 ATOM 1136 C CB . ALA A 1 163 ? 67.883 15.315 37.146 1.00 24.22 ? 378 ALA A CB 1 ATOM 1137 N N . VAL A 1 164 ? 68.345 15.846 33.960 1.00 28.06 ? 379 VAL A N 1 ATOM 1138 C CA . VAL A 1 164 ? 69.275 15.686 32.852 1.00 31.53 ? 379 VAL A CA 1 ATOM 1139 C C . VAL A 1 164 ? 70.059 16.944 32.562 1.00 32.54 ? 379 VAL A C 1 ATOM 1140 O O . VAL A 1 164 ? 69.474 17.987 32.326 1.00 34.85 ? 379 VAL A O 1 ATOM 1141 C CB . VAL A 1 164 ? 68.559 15.260 31.541 1.00 31.93 ? 379 VAL A CB 1 ATOM 1142 C CG1 . VAL A 1 164 ? 69.571 15.174 30.387 1.00 32.01 ? 379 VAL A CG1 1 ATOM 1143 C CG2 . VAL A 1 164 ? 67.910 13.917 31.721 1.00 32.53 ? 379 VAL A CG2 1 ATOM 1144 N N . GLU A 1 165 ? 71.384 16.848 32.577 1.00 33.74 ? 380 GLU A N 1 ATOM 1145 C CA . GLU A 1 165 ? 72.201 18.005 32.271 1.00 36.20 ? 380 GLU A CA 1 ATOM 1146 C C . GLU A 1 165 ? 73.401 17.637 31.418 1.00 37.05 ? 380 GLU A C 1 ATOM 1147 O O . GLU A 1 165 ? 74.060 16.631 31.638 1.00 38.11 ? 380 GLU A O 1 ATOM 1148 C CB . GLU A 1 165 ? 72.629 18.733 33.551 1.00 38.75 ? 380 GLU A CB 1 ATOM 1149 C CG . GLU A 1 165 ? 73.557 17.980 34.497 1.00 46.05 ? 380 GLU A CG 1 ATOM 1150 C CD . GLU A 1 165 ? 73.727 18.686 35.860 1.00 49.47 ? 380 GLU A CD 1 ATOM 1151 O OE1 . GLU A 1 165 ? 74.055 19.896 35.889 1.00 51.83 ? 380 GLU A OE1 1 ATOM 1152 O OE2 . GLU A 1 165 ? 73.539 18.025 36.908 1.00 52.35 ? 380 GLU A OE2 1 ATOM 1153 N N . TRP A 1 166 ? 73.648 18.454 30.407 1.00 39.27 ? 381 TRP A N 1 ATOM 1154 C CA . TRP A 1 166 ? 74.756 18.250 29.492 1.00 40.65 ? 381 TRP A CA 1 ATOM 1155 C C . TRP A 1 166 ? 75.990 18.891 30.055 1.00 42.52 ? 381 TRP A C 1 ATOM 1156 O O . TRP A 1 166 ? 75.895 19.822 30.847 1.00 44.36 ? 381 TRP A O 1 ATOM 1157 C CB . TRP A 1 166 ? 74.460 18.887 28.140 1.00 39.16 ? 381 TRP A CB 1 ATOM 1158 C CG . TRP A 1 166 ? 73.579 18.075 27.297 1.00 34.77 ? 381 TRP A CG 1 ATOM 1159 C CD1 . TRP A 1 166 ? 72.230 18.090 27.278 1.00 33.00 ? 381 TRP A CD1 1 ATOM 1160 C CD2 . TRP A 1 166 ? 73.991 17.110 26.335 1.00 33.80 ? 381 TRP A CD2 1 ATOM 1161 N NE1 . TRP A 1 166 ? 71.761 17.191 26.351 1.00 33.86 ? 381 TRP A NE1 1 ATOM 1162 C CE2 . TRP A 1 166 ? 72.826 16.577 25.756 1.00 33.38 ? 381 TRP A CE2 1 ATOM 1163 C CE3 . TRP A 1 166 ? 75.237 16.646 25.902 1.00 34.03 ? 381 TRP A CE3 1 ATOM 1164 C CZ2 . TRP A 1 166 ? 72.862 15.602 24.766 1.00 34.92 ? 381 TRP A CZ2 1 ATOM 1165 C CZ3 . TRP A 1 166 ? 75.278 15.675 24.916 1.00 35.08 ? 381 TRP A CZ3 1 ATOM 1166 C CH2 . TRP A 1 166 ? 74.098 15.163 24.356 1.00 35.42 ? 381 TRP A CH2 1 ATOM 1167 N N . GLU A 1 167 ? 77.146 18.410 29.622 1.00 44.15 ? 382 GLU A N 1 ATOM 1168 C CA . GLU A 1 167 ? 78.398 18.952 30.098 1.00 48.10 ? 382 GLU A CA 1 ATOM 1169 C C . GLU A 1 167 ? 79.583 18.630 29.191 1.00 50.53 ? 382 GLU A C 1 ATOM 1170 O O . GLU A 1 167 ? 79.575 17.642 28.463 1.00 51.62 ? 382 GLU A O 1 ATOM 1171 C CB . GLU A 1 167 ? 78.656 18.458 31.528 1.00 47.90 ? 382 GLU A CB 1 ATOM 1172 C CG . GLU A 1 167 ? 78.324 16.996 31.771 1.00 50.20 ? 382 GLU A CG 1 ATOM 1173 C CD . GLU A 1 167 ? 78.696 16.549 33.177 1.00 54.35 ? 382 GLU A CD 1 ATOM 1174 O OE1 . GLU A 1 167 ? 79.894 16.642 33.530 1.00 55.87 ? 382 GLU A OE1 1 ATOM 1175 O OE2 . GLU A 1 167 ? 77.798 16.105 33.936 1.00 56.11 ? 382 GLU A OE2 1 ATOM 1176 N N . SER A 1 168 ? 80.598 19.485 29.241 1.00 53.94 ? 383 SER A N 1 ATOM 1177 C CA . SER A 1 168 ? 81.808 19.320 28.446 1.00 58.04 ? 383 SER A CA 1 ATOM 1178 C C . SER A 1 168 ? 82.984 19.799 29.276 1.00 60.93 ? 383 SER A C 1 ATOM 1179 O O . SER A 1 168 ? 82.831 20.695 30.116 1.00 60.90 ? 383 SER A O 1 ATOM 1180 C CB . SER A 1 168 ? 81.726 20.150 27.160 1.00 58.88 ? 383 SER A CB 1 ATOM 1181 O OG . SER A 1 168 ? 82.934 20.084 26.419 1.00 59.25 ? 383 SER A OG 1 ATOM 1182 N N . ASN A 1 169 ? 84.149 19.194 29.040 1.00 63.47 ? 384 ASN A N 1 ATOM 1183 C CA . ASN A 1 169 ? 85.384 19.539 29.745 1.00 65.41 ? 384 ASN A CA 1 ATOM 1184 C C . ASN A 1 169 ? 85.179 20.153 31.140 1.00 66.26 ? 384 ASN A C 1 ATOM 1185 O O . ASN A 1 169 ? 85.775 21.182 31.470 1.00 66.93 ? 384 ASN A O 1 ATOM 1186 C CB . ASN A 1 169 ? 86.216 20.495 28.885 1.00 67.38 ? 384 ASN A CB 1 ATOM 1187 C CG . ASN A 1 169 ? 86.426 19.975 27.474 1.00 70.43 ? 384 ASN A CG 1 ATOM 1188 O OD1 . ASN A 1 169 ? 86.904 18.858 27.279 1.00 72.20 ? 384 ASN A OD1 1 ATOM 1189 N ND2 . ASN A 1 169 ? 86.070 20.786 26.478 1.00 71.92 ? 384 ASN A ND2 1 ATOM 1190 N N . GLY A 1 170 ? 84.326 19.533 31.951 1.00 65.53 ? 385 GLY A N 1 ATOM 1191 C CA . GLY A 1 170 ? 84.101 20.037 33.293 1.00 64.06 ? 385 GLY A CA 1 ATOM 1192 C C . GLY A 1 170 ? 82.921 20.967 33.497 1.00 63.74 ? 385 GLY A C 1 ATOM 1193 O O . GLY A 1 170 ? 81.942 20.608 34.157 1.00 64.55 ? 385 GLY A O 1 ATOM 1194 N N . GLN A 1 171 ? 83.001 22.170 32.944 1.00 61.89 ? 386 GLN A N 1 ATOM 1195 C CA . GLN A 1 171 ? 81.913 23.120 33.123 1.00 60.13 ? 386 GLN A CA 1 ATOM 1196 C C . GLN A 1 171 ? 80.645 22.588 32.475 1.00 56.65 ? 386 GLN A C 1 ATOM 1197 O O . GLN A 1 171 ? 80.704 21.817 31.523 1.00 54.92 ? 386 GLN A O 1 ATOM 1198 C CB . GLN A 1 171 ? 82.241 24.483 32.488 1.00 63.62 ? 386 GLN A CB 1 ATOM 1199 C CG . GLN A 1 171 ? 83.721 24.869 32.391 1.00 67.79 ? 386 GLN A CG 1 ATOM 1200 C CD . GLN A 1 171 ? 84.427 24.876 33.733 1.00 70.92 ? 386 GLN A CD 1 ATOM 1201 O OE1 . GLN A 1 171 ? 83.859 25.313 34.742 1.00 72.03 ? 386 GLN A OE1 1 ATOM 1202 N NE2 . GLN A 1 171 ? 85.679 24.402 33.754 1.00 71.21 ? 386 GLN A NE2 1 ATOM 1203 N N . PRO A 1 172 ? 79.477 22.982 33.002 1.00 54.22 ? 387 PRO A N 1 ATOM 1204 C CA . PRO A 1 172 ? 78.208 22.536 32.440 1.00 52.96 ? 387 PRO A CA 1 ATOM 1205 C C . PRO A 1 172 ? 78.000 23.234 31.106 1.00 52.76 ? 387 PRO A C 1 ATOM 1206 O O . PRO A 1 172 ? 78.938 23.798 30.546 1.00 53.20 ? 387 PRO A O 1 ATOM 1207 C CB . PRO A 1 172 ? 77.197 22.966 33.491 1.00 51.95 ? 387 PRO A CB 1 ATOM 1208 C CG . PRO A 1 172 ? 77.817 24.157 34.086 1.00 52.08 ? 387 PRO A CG 1 ATOM 1209 C CD . PRO A 1 172 ? 79.251 23.752 34.233 1.00 53.53 ? 387 PRO A CD 1 ATOM 1210 N N . GLU A 1 173 ? 76.775 23.208 30.602 1.00 52.68 ? 388 GLU A N 1 ATOM 1211 C CA . GLU A 1 173 ? 76.483 23.823 29.319 1.00 52.50 ? 388 GLU A CA 1 ATOM 1212 C C . GLU A 1 173 ? 75.312 24.786 29.397 1.00 52.70 ? 388 GLU A C 1 ATOM 1213 O O . GLU A 1 173 ? 74.442 24.649 30.254 1.00 51.21 ? 388 GLU A O 1 ATOM 1214 C CB . GLU A 1 173 ? 76.228 22.727 28.291 1.00 51.76 ? 388 GLU A CB 1 ATOM 1215 C CG . GLU A 1 173 ? 77.501 22.061 27.818 1.00 52.72 ? 388 GLU A CG 1 ATOM 1216 C CD . GLU A 1 173 ? 78.152 22.806 26.659 1.00 55.82 ? 388 GLU A CD 1 ATOM 1217 O OE1 . GLU A 1 173 ? 79.317 22.494 26.317 1.00 55.54 ? 388 GLU A OE1 1 ATOM 1218 O OE2 . GLU A 1 173 ? 77.492 23.699 26.078 1.00 57.81 ? 388 GLU A OE2 1 ATOM 1219 N N . ASN A 1 174 ? 75.287 25.764 28.497 1.00 54.33 ? 389 ASN A N 1 ATOM 1220 C CA . ASN A 1 174 ? 74.222 26.765 28.519 1.00 55.64 ? 389 ASN A CA 1 ATOM 1221 C C . ASN A 1 174 ? 73.095 26.502 27.558 1.00 54.97 ? 389 ASN A C 1 ATOM 1222 O O . ASN A 1 174 ? 71.919 26.550 27.938 1.00 56.60 ? 389 ASN A O 1 ATOM 1223 C CB . ASN A 1 174 ? 74.777 28.154 28.225 1.00 56.53 ? 389 ASN A CB 1 ATOM 1224 C CG . ASN A 1 174 ? 76.272 28.161 28.144 1.00 60.14 ? 389 ASN A CG 1 ATOM 1225 O OD1 . ASN A 1 174 ? 76.857 27.578 27.229 1.00 62.38 ? 389 ASN A OD1 1 ATOM 1226 N ND2 . ASN A 1 174 ? 76.914 28.809 29.114 1.00 62.46 ? 389 ASN A ND2 1 ATOM 1227 N N . ASN A 1 175 ? 73.432 26.222 26.308 1.00 50.62 ? 390 ASN A N 1 ATOM 1228 C CA . ASN A 1 175 ? 72.373 26.010 25.366 1.00 46.06 ? 390 ASN A CA 1 ATOM 1229 C C . ASN A 1 175 ? 71.907 24.575 25.184 1.00 45.24 ? 390 ASN A C 1 ATOM 1230 O O . ASN A 1 175 ? 72.332 23.881 24.261 1.00 44.71 ? 390 ASN A O 1 ATOM 1231 C CB . ASN A 1 175 ? 72.746 26.625 24.034 1.00 44.12 ? 390 ASN A CB 1 ATOM 1232 C CG . ASN A 1 175 ? 71.545 27.153 23.314 1.00 44.91 ? 390 ASN A CG 1 ATOM 1233 O OD1 . ASN A 1 175 ? 70.449 27.186 23.877 1.00 41.75 ? 390 ASN A OD1 1 ATOM 1234 N ND2 . ASN A 1 175 ? 71.730 27.576 22.065 1.00 45.74 ? 390 ASN A ND2 1 ATOM 1235 N N . TYR A 1 176 ? 71.031 24.143 26.090 1.00 43.18 ? 391 TYR A N 1 ATOM 1236 C CA . TYR A 1 176 ? 70.427 22.822 26.036 1.00 40.64 ? 391 TYR A CA 1 ATOM 1237 C C . TYR A 1 176 ? 69.086 22.891 26.735 1.00 39.47 ? 391 TYR A C 1 ATOM 1238 O O . TYR A 1 176 ? 68.934 23.603 27.713 1.00 40.91 ? 391 TYR A O 1 ATOM 1239 C CB . TYR A 1 176 ? 71.324 21.763 26.678 1.00 40.72 ? 391 TYR A CB 1 ATOM 1240 C CG . TYR A 1 176 ? 71.324 21.672 28.198 1.00 42.07 ? 391 TYR A CG 1 ATOM 1241 C CD1 . TYR A 1 176 ? 70.311 21.002 28.891 1.00 39.34 ? 391 TYR A CD1 1 ATOM 1242 C CD2 . TYR A 1 176 ? 72.372 22.216 28.944 1.00 43.20 ? 391 TYR A CD2 1 ATOM 1243 C CE1 . TYR A 1 176 ? 70.348 20.878 30.287 1.00 36.96 ? 391 TYR A CE1 1 ATOM 1244 C CE2 . TYR A 1 176 ? 72.413 22.094 30.335 1.00 40.18 ? 391 TYR A CE2 1 ATOM 1245 C CZ . TYR A 1 176 ? 71.403 21.430 30.994 1.00 37.69 ? 391 TYR A CZ 1 ATOM 1246 O OH . TYR A 1 176 ? 71.462 21.350 32.363 1.00 37.59 ? 391 TYR A OH 1 ATOM 1247 N N . LYS A 1 177 ? 68.107 22.175 26.200 1.00 38.85 ? 392 LYS A N 1 ATOM 1248 C CA . LYS A 1 177 ? 66.757 22.129 26.750 1.00 37.11 ? 392 LYS A CA 1 ATOM 1249 C C . LYS A 1 177 ? 66.350 20.666 26.829 1.00 38.01 ? 392 LYS A C 1 ATOM 1250 O O . LYS A 1 177 ? 66.837 19.841 26.056 1.00 39.95 ? 392 LYS A O 1 ATOM 1251 C CB . LYS A 1 177 ? 65.812 22.851 25.815 1.00 36.01 ? 392 LYS A CB 1 ATOM 1252 C CG . LYS A 1 177 ? 66.135 24.297 25.638 1.00 37.33 ? 392 LYS A CG 1 ATOM 1253 C CD . LYS A 1 177 ? 65.535 25.106 26.773 1.00 40.11 ? 392 LYS A CD 1 ATOM 1254 C CE . LYS A 1 177 ? 65.916 26.579 26.700 1.00 38.94 ? 392 LYS A CE 1 ATOM 1255 N NZ . LYS A 1 177 ? 65.322 27.286 27.861 1.00 41.37 ? 392 LYS A NZ 1 ATOM 1256 N N . THR A 1 178 ? 65.458 20.323 27.744 1.00 37.03 ? 393 THR A N 1 ATOM 1257 C CA . THR A 1 178 ? 65.054 18.931 27.836 1.00 37.44 ? 393 THR A CA 1 ATOM 1258 C C . THR A 1 178 ? 63.551 18.717 27.835 1.00 36.58 ? 393 THR A C 1 ATOM 1259 O O . THR A 1 178 ? 62.833 19.261 28.668 1.00 38.83 ? 393 THR A O 1 ATOM 1260 C CB . THR A 1 178 ? 65.640 18.278 29.082 1.00 38.47 ? 393 THR A CB 1 ATOM 1261 O OG1 . THR A 1 178 ? 67.067 18.369 29.034 1.00 41.36 ? 393 THR A OG1 1 ATOM 1262 C CG2 . THR A 1 178 ? 65.240 16.818 29.153 1.00 39.63 ? 393 THR A CG2 1 ATOM 1263 N N . THR A 1 179 ? 63.078 17.903 26.901 1.00 33.68 ? 394 THR A N 1 ATOM 1264 C CA . THR A 1 179 ? 61.654 17.629 26.804 1.00 30.33 ? 394 THR A CA 1 ATOM 1265 C C . THR A 1 179 ? 61.145 17.077 28.120 1.00 27.05 ? 394 THR A C 1 ATOM 1266 O O . THR A 1 179 ? 61.917 16.605 28.945 1.00 27.62 ? 394 THR A O 1 ATOM 1267 C CB . THR A 1 179 ? 61.357 16.571 25.723 1.00 31.84 ? 394 THR A CB 1 ATOM 1268 O OG1 . THR A 1 179 ? 62.012 15.350 26.076 1.00 33.64 ? 394 THR A OG1 1 ATOM 1269 C CG2 . THR A 1 179 ? 61.849 17.026 24.353 1.00 31.10 ? 394 THR A CG2 1 ATOM 1270 N N . PRO A 1 180 ? 59.834 17.151 28.345 1.00 24.77 ? 395 PRO A N 1 ATOM 1271 C CA . PRO A 1 180 ? 59.285 16.615 29.592 1.00 24.09 ? 395 PRO A CA 1 ATOM 1272 C C . PRO A 1 180 ? 59.260 15.106 29.409 1.00 25.85 ? 395 PRO A C 1 ATOM 1273 O O . PRO A 1 180 ? 59.363 14.606 28.281 1.00 27.03 ? 395 PRO A O 1 ATOM 1274 C CB . PRO A 1 180 ? 57.868 17.174 29.628 1.00 22.45 ? 395 PRO A CB 1 ATOM 1275 C CG . PRO A 1 180 ? 57.918 18.373 28.733 1.00 22.33 ? 395 PRO A CG 1 ATOM 1276 C CD . PRO A 1 180 ? 58.836 17.956 27.629 1.00 23.05 ? 395 PRO A CD 1 ATOM 1277 N N . PRO A 1 181 ? 59.132 14.349 30.501 1.00 25.59 ? 396 PRO A N 1 ATOM 1278 C CA . PRO A 1 181 ? 59.097 12.904 30.309 1.00 26.46 ? 396 PRO A CA 1 ATOM 1279 C C . PRO A 1 181 ? 57.851 12.607 29.483 1.00 27.63 ? 396 PRO A C 1 ATOM 1280 O O . PRO A 1 181 ? 56.918 13.412 29.442 1.00 31.28 ? 396 PRO A O 1 ATOM 1281 C CB . PRO A 1 181 ? 58.968 12.374 31.728 1.00 25.39 ? 396 PRO A CB 1 ATOM 1282 C CG . PRO A 1 181 ? 59.618 13.409 32.538 1.00 24.87 ? 396 PRO A CG 1 ATOM 1283 C CD . PRO A 1 181 ? 59.097 14.676 31.928 1.00 25.20 ? 396 PRO A CD 1 ATOM 1284 N N . VAL A 1 182 ? 57.835 11.462 28.821 1.00 26.59 ? 397 VAL A N 1 ATOM 1285 C CA . VAL A 1 182 ? 56.698 11.080 28.007 1.00 23.49 ? 397 VAL A CA 1 ATOM 1286 C C . VAL A 1 182 ? 56.396 9.605 28.185 1.00 26.20 ? 397 VAL A C 1 ATOM 1287 O O . VAL A 1 182 ? 57.303 8.754 28.101 1.00 26.68 ? 397 VAL A O 1 ATOM 1288 C CB . VAL A 1 182 ? 56.985 11.320 26.561 1.00 20.97 ? 397 VAL A CB 1 ATOM 1289 C CG1 . VAL A 1 182 ? 55.798 10.938 25.755 1.00 20.66 ? 397 VAL A CG1 1 ATOM 1290 C CG2 . VAL A 1 182 ? 57.384 12.770 26.350 1.00 20.82 ? 397 VAL A CG2 1 ATOM 1291 N N . LEU A 1 183 ? 55.119 9.311 28.420 1.00 25.30 ? 398 LEU A N 1 ATOM 1292 C CA . LEU A 1 183 ? 54.650 7.946 28.630 1.00 25.61 ? 398 LEU A CA 1 ATOM 1293 C C . LEU A 1 183 ? 54.678 7.100 27.359 1.00 26.73 ? 398 LEU A C 1 ATOM 1294 O O . LEU A 1 183 ? 53.901 7.342 26.443 1.00 26.10 ? 398 LEU A O 1 ATOM 1295 C CB . LEU A 1 183 ? 53.236 7.991 29.175 1.00 24.41 ? 398 LEU A CB 1 ATOM 1296 C CG . LEU A 1 183 ? 52.627 6.687 29.669 1.00 23.62 ? 398 LEU A CG 1 ATOM 1297 C CD1 . LEU A 1 183 ? 53.540 6.017 30.668 1.00 24.77 ? 398 LEU A CD1 1 ATOM 1298 C CD2 . LEU A 1 183 ? 51.291 6.999 30.288 1.00 19.34 ? 398 LEU A CD2 1 ATOM 1299 N N . ASP A 1 184 ? 55.570 6.108 27.318 1.00 29.12 ? 399 ASP A N 1 ATOM 1300 C CA . ASP A 1 184 ? 55.712 5.226 26.155 1.00 30.55 ? 399 ASP A CA 1 ATOM 1301 C C . ASP A 1 184 ? 54.610 4.169 26.116 1.00 31.07 ? 399 ASP A C 1 ATOM 1302 O O . ASP A 1 184 ? 53.765 4.102 27.008 1.00 32.38 ? 399 ASP A O 1 ATOM 1303 C CB . ASP A 1 184 ? 57.080 4.527 26.158 1.00 30.84 ? 399 ASP A CB 1 ATOM 1304 C CG . ASP A 1 184 ? 57.656 4.366 24.756 1.00 33.30 ? 399 ASP A CG 1 ATOM 1305 O OD1 . ASP A 1 184 ? 56.867 4.184 23.806 1.00 34.05 ? 399 ASP A OD1 1 ATOM 1306 O OD2 . ASP A 1 184 ? 58.898 4.417 24.593 1.00 34.44 ? 399 ASP A OD2 1 ATOM 1307 N N . SER A 1 185 ? 54.632 3.337 25.084 1.00 31.10 ? 400 SER A N 1 ATOM 1308 C CA . SER A 1 185 ? 53.617 2.310 24.910 1.00 32.59 ? 400 SER A CA 1 ATOM 1309 C C . SER A 1 185 ? 53.776 1.106 25.813 1.00 32.18 ? 400 SER A C 1 ATOM 1310 O O . SER A 1 185 ? 52.817 0.356 26.029 1.00 29.91 ? 400 SER A O 1 ATOM 1311 C CB . SER A 1 185 ? 53.573 1.857 23.445 1.00 35.46 ? 400 SER A CB 1 ATOM 1312 O OG . SER A 1 185 ? 54.872 1.615 22.927 1.00 37.80 ? 400 SER A OG 1 ATOM 1313 N N . ASP A 1 186 ? 54.985 0.929 26.341 1.00 33.01 ? 401 ASP A N 1 ATOM 1314 C CA . ASP A 1 186 ? 55.281 -0.189 27.233 1.00 32.04 ? 401 ASP A CA 1 ATOM 1315 C C . ASP A 1 186 ? 55.081 0.179 28.693 1.00 30.56 ? 401 ASP A C 1 ATOM 1316 O O . ASP A 1 186 ? 55.378 -0.616 29.574 1.00 32.87 ? 401 ASP A O 1 ATOM 1317 C CB . ASP A 1 186 ? 56.718 -0.665 27.041 1.00 34.75 ? 401 ASP A CB 1 ATOM 1318 C CG . ASP A 1 186 ? 57.734 0.333 27.561 1.00 38.05 ? 401 ASP A CG 1 ATOM 1319 O OD1 . ASP A 1 186 ? 57.311 1.349 28.163 1.00 39.92 ? 401 ASP A OD1 1 ATOM 1320 O OD2 . ASP A 1 186 ? 58.951 0.103 27.374 1.00 38.97 ? 401 ASP A OD2 1 ATOM 1321 N N . GLY A 1 187 ? 54.614 1.394 28.956 1.00 29.44 ? 402 GLY A N 1 ATOM 1322 C CA . GLY A 1 187 ? 54.375 1.799 30.326 1.00 25.35 ? 402 GLY A CA 1 ATOM 1323 C C . GLY A 1 187 ? 55.467 2.605 30.976 1.00 24.69 ? 402 GLY A C 1 ATOM 1324 O O . GLY A 1 187 ? 55.251 3.181 32.032 1.00 24.24 ? 402 GLY A O 1 ATOM 1325 N N . SER A 1 188 ? 56.647 2.651 30.376 1.00 24.61 ? 403 SER A N 1 ATOM 1326 C CA . SER A 1 188 ? 57.725 3.426 30.963 1.00 26.52 ? 403 SER A CA 1 ATOM 1327 C C . SER A 1 188 ? 57.777 4.807 30.318 1.00 27.85 ? 403 SER A C 1 ATOM 1328 O O . SER A 1 188 ? 56.935 5.133 29.486 1.00 28.94 ? 403 SER A O 1 ATOM 1329 C CB . SER A 1 188 ? 59.045 2.705 30.767 1.00 26.31 ? 403 SER A CB 1 ATOM 1330 O OG . SER A 1 188 ? 59.326 2.588 29.395 1.00 30.45 ? 403 SER A OG 1 ATOM 1331 N N . PHE A 1 189 ? 58.758 5.621 30.698 1.00 28.37 ? 404 PHE A N 1 ATOM 1332 C CA . PHE A 1 189 ? 58.877 6.963 30.137 1.00 29.59 ? 404 PHE A CA 1 ATOM 1333 C C . PHE A 1 189 ? 60.122 7.131 29.311 1.00 30.21 ? 404 PHE A C 1 ATOM 1334 O O . PHE A 1 189 ? 61.075 6.376 29.465 1.00 31.98 ? 404 PHE A O 1 ATOM 1335 C CB . PHE A 1 189 ? 58.920 8.022 31.241 1.00 29.73 ? 404 PHE A CB 1 ATOM 1336 C CG . PHE A 1 189 ? 57.613 8.244 31.924 1.00 31.03 ? 404 PHE A CG 1 ATOM 1337 C CD1 . PHE A 1 189 ? 57.211 7.428 32.972 1.00 31.69 ? 404 PHE A CD1 1 ATOM 1338 C CD2 . PHE A 1 189 ? 56.778 9.275 31.523 1.00 32.10 ? 404 PHE A CD2 1 ATOM 1339 C CE1 . PHE A 1 189 ? 55.996 7.640 33.614 1.00 30.69 ? 404 PHE A CE1 1 ATOM 1340 C CE2 . PHE A 1 189 ? 55.559 9.492 32.162 1.00 32.70 ? 404 PHE A CE2 1 ATOM 1341 C CZ . PHE A 1 189 ? 55.171 8.672 33.210 1.00 31.72 ? 404 PHE A CZ 1 ATOM 1342 N N . PHE A 1 190 ? 60.106 8.136 28.439 1.00 29.64 ? 405 PHE A N 1 ATOM 1343 C CA . PHE A 1 190 ? 61.260 8.459 27.608 1.00 30.01 ? 405 PHE A CA 1 ATOM 1344 C C . PHE A 1 190 ? 61.301 9.969 27.428 1.00 31.07 ? 405 PHE A C 1 ATOM 1345 O O . PHE A 1 190 ? 60.277 10.635 27.466 1.00 31.13 ? 405 PHE A O 1 ATOM 1346 C CB . PHE A 1 190 ? 61.185 7.766 26.234 1.00 29.81 ? 405 PHE A CB 1 ATOM 1347 C CG . PHE A 1 190 ? 60.291 8.459 25.238 1.00 31.00 ? 405 PHE A CG 1 ATOM 1348 C CD1 . PHE A 1 190 ? 60.758 9.537 24.492 1.00 31.29 ? 405 PHE A CD1 1 ATOM 1349 C CD2 . PHE A 1 190 ? 58.958 8.060 25.076 1.00 32.11 ? 405 PHE A CD2 1 ATOM 1350 C CE1 . PHE A 1 190 ? 59.903 10.213 23.598 1.00 30.65 ? 405 PHE A CE1 1 ATOM 1351 C CE2 . PHE A 1 190 ? 58.099 8.725 24.190 1.00 29.60 ? 405 PHE A CE2 1 ATOM 1352 C CZ . PHE A 1 190 ? 58.571 9.804 23.450 1.00 28.46 ? 405 PHE A CZ 1 ATOM 1353 N N . LEU A 1 191 ? 62.495 10.516 27.277 1.00 31.96 ? 406 LEU A N 1 ATOM 1354 C CA . LEU A 1 191 ? 62.636 11.941 27.055 1.00 31.35 ? 406 LEU A CA 1 ATOM 1355 C C . LEU A 1 191 ? 63.884 12.155 26.233 1.00 31.34 ? 406 LEU A C 1 ATOM 1356 O O . LEU A 1 191 ? 64.747 11.284 26.163 1.00 34.40 ? 406 LEU A O 1 ATOM 1357 C CB . LEU A 1 191 ? 62.734 12.712 28.372 1.00 31.42 ? 406 LEU A CB 1 ATOM 1358 C CG . LEU A 1 191 ? 63.915 12.490 29.324 1.00 33.14 ? 406 LEU A CG 1 ATOM 1359 C CD1 . LEU A 1 191 ? 65.271 12.763 28.666 1.00 29.83 ? 406 LEU A CD1 1 ATOM 1360 C CD2 . LEU A 1 191 ? 63.710 13.420 30.514 1.00 30.75 ? 406 LEU A CD2 1 ATOM 1361 N N . TYR A 1 192 ? 63.962 13.312 25.601 1.00 28.42 ? 407 TYR A N 1 ATOM 1362 C CA . TYR A 1 192 ? 65.094 13.668 24.786 1.00 27.06 ? 407 TYR A CA 1 ATOM 1363 C C . TYR A 1 192 ? 65.623 14.981 25.332 1.00 28.12 ? 407 TYR A C 1 ATOM 1364 O O . TYR A 1 192 ? 64.851 15.844 25.762 1.00 27.17 ? 407 TYR A O 1 ATOM 1365 C CB . TYR A 1 192 ? 64.650 13.902 23.349 1.00 26.21 ? 407 TYR A CB 1 ATOM 1366 C CG . TYR A 1 192 ? 64.430 12.671 22.497 1.00 28.00 ? 407 TYR A CG 1 ATOM 1367 C CD1 . TYR A 1 192 ? 65.509 12.028 21.882 1.00 27.88 ? 407 TYR A CD1 1 ATOM 1368 C CD2 . TYR A 1 192 ? 63.134 12.198 22.232 1.00 25.52 ? 407 TYR A CD2 1 ATOM 1369 C CE1 . TYR A 1 192 ? 65.311 10.954 21.008 1.00 26.77 ? 407 TYR A CE1 1 ATOM 1370 C CE2 . TYR A 1 192 ? 62.924 11.127 21.373 1.00 25.44 ? 407 TYR A CE2 1 ATOM 1371 C CZ . TYR A 1 192 ? 64.021 10.512 20.756 1.00 27.74 ? 407 TYR A CZ 1 ATOM 1372 O OH . TYR A 1 192 ? 63.830 9.494 19.851 1.00 27.50 ? 407 TYR A OH 1 ATOM 1373 N N . SER A 1 193 ? 66.938 15.139 25.333 1.00 26.96 ? 408 SER A N 1 ATOM 1374 C CA . SER A 1 193 ? 67.499 16.402 25.768 1.00 26.46 ? 408 SER A CA 1 ATOM 1375 C C . SER A 1 193 ? 68.245 16.904 24.565 1.00 26.71 ? 408 SER A C 1 ATOM 1376 O O . SER A 1 193 ? 68.883 16.110 23.870 1.00 28.92 ? 408 SER A O 1 ATOM 1377 C CB . SER A 1 193 ? 68.471 16.223 26.915 1.00 26.91 ? 408 SER A CB 1 ATOM 1378 O OG . SER A 1 193 ? 68.751 17.487 27.465 1.00 25.99 ? 408 SER A OG 1 ATOM 1379 N N . LYS A 1 194 ? 68.179 18.207 24.313 1.00 25.44 ? 409 LYS A N 1 ATOM 1380 C CA . LYS A 1 194 ? 68.855 18.771 23.155 1.00 26.79 ? 409 LYS A CA 1 ATOM 1381 C C . LYS A 1 194 ? 69.940 19.784 23.506 1.00 28.22 ? 409 LYS A C 1 ATOM 1382 O O . LYS A 1 194 ? 69.668 20.806 24.133 1.00 27.60 ? 409 LYS A O 1 ATOM 1383 C CB . LYS A 1 194 ? 67.829 19.427 22.233 1.00 26.80 ? 409 LYS A CB 1 ATOM 1384 C CG . LYS A 1 194 ? 68.376 19.832 20.880 1.00 27.04 ? 409 LYS A CG 1 ATOM 1385 C CD . LYS A 1 194 ? 67.255 20.222 19.933 1.00 30.26 ? 409 LYS A CD 1 ATOM 1386 C CE . LYS A 1 194 ? 66.520 21.499 20.356 1.00 28.52 ? 409 LYS A CE 1 ATOM 1387 N NZ . LYS A 1 194 ? 67.366 22.677 20.019 1.00 34.70 ? 409 LYS A NZ 1 ATOM 1388 N N . LEU A 1 195 ? 71.174 19.488 23.108 1.00 28.49 ? 410 LEU A N 1 ATOM 1389 C CA . LEU A 1 195 ? 72.285 20.394 23.355 1.00 31.00 ? 410 LEU A CA 1 ATOM 1390 C C . LEU A 1 195 ? 72.614 21.055 22.041 1.00 34.07 ? 410 LEU A C 1 ATOM 1391 O O . LEU A 1 195 ? 72.735 20.374 21.033 1.00 36.67 ? 410 LEU A O 1 ATOM 1392 C CB . LEU A 1 195 ? 73.533 19.654 23.836 1.00 29.74 ? 410 LEU A CB 1 ATOM 1393 C CG . LEU A 1 195 ? 74.830 20.487 23.844 1.00 28.38 ? 410 LEU A CG 1 ATOM 1394 C CD1 . LEU A 1 195 ? 74.740 21.626 24.821 1.00 26.86 ? 410 LEU A CD1 1 ATOM 1395 C CD2 . LEU A 1 195 ? 75.982 19.620 24.234 1.00 28.10 ? 410 LEU A CD2 1 ATOM 1396 N N . THR A 1 196 ? 72.745 22.379 22.053 1.00 36.14 ? 411 THR A N 1 ATOM 1397 C CA . THR A 1 196 ? 73.090 23.146 20.858 1.00 35.83 ? 411 THR A CA 1 ATOM 1398 C C . THR A 1 196 ? 74.507 23.665 21.062 1.00 35.93 ? 411 THR A C 1 ATOM 1399 O O . THR A 1 196 ? 74.835 24.160 22.140 1.00 36.21 ? 411 THR A O 1 ATOM 1400 C CB . THR A 1 196 ? 72.145 24.317 20.692 1.00 35.80 ? 411 THR A CB 1 ATOM 1401 O OG1 . THR A 1 196 ? 70.819 23.815 20.484 1.00 41.12 ? 411 THR A OG1 1 ATOM 1402 C CG2 . THR A 1 196 ? 72.561 25.176 19.519 1.00 35.53 ? 411 THR A CG2 1 ATOM 1403 N N . VAL A 1 197 ? 75.349 23.548 20.043 1.00 34.29 ? 412 VAL A N 1 ATOM 1404 C CA . VAL A 1 197 ? 76.724 23.989 20.178 1.00 36.38 ? 412 VAL A CA 1 ATOM 1405 C C . VAL A 1 197 ? 77.239 24.628 18.911 1.00 39.37 ? 412 VAL A C 1 ATOM 1406 O O . VAL A 1 197 ? 76.806 24.255 17.831 1.00 43.07 ? 412 VAL A O 1 ATOM 1407 C CB . VAL A 1 197 ? 77.631 22.812 20.503 1.00 34.47 ? 412 VAL A CB 1 ATOM 1408 C CG1 . VAL A 1 197 ? 77.178 22.158 21.768 1.00 36.33 ? 412 VAL A CG1 1 ATOM 1409 C CG2 . VAL A 1 197 ? 77.594 21.819 19.385 1.00 34.36 ? 412 VAL A CG2 1 ATOM 1410 N N . ASP A 1 198 ? 78.158 25.585 19.031 1.00 40.86 ? 413 ASP A N 1 ATOM 1411 C CA . ASP A 1 198 ? 78.726 26.215 17.842 1.00 42.28 ? 413 ASP A CA 1 ATOM 1412 C C . ASP A 1 198 ? 79.299 25.082 16.971 1.00 42.61 ? 413 ASP A C 1 ATOM 1413 O O . ASP A 1 198 ? 80.127 24.277 17.415 1.00 42.43 ? 413 ASP A O 1 ATOM 1414 C CB . ASP A 1 198 ? 79.836 27.217 18.216 1.00 44.49 ? 413 ASP A CB 1 ATOM 1415 C CG . ASP A 1 198 ? 79.288 28.556 18.746 1.00 48.58 ? 413 ASP A CG 1 ATOM 1416 O OD1 . ASP A 1 198 ? 78.564 29.247 17.995 1.00 51.62 ? 413 ASP A OD1 1 ATOM 1417 O OD2 . ASP A 1 198 ? 79.586 28.932 19.908 1.00 49.69 ? 413 ASP A OD2 1 ATOM 1418 N N . LYS A 1 199 ? 78.824 25.005 15.738 1.00 41.15 ? 414 LYS A N 1 ATOM 1419 C CA . LYS A 1 199 ? 79.267 23.985 14.809 1.00 41.01 ? 414 LYS A CA 1 ATOM 1420 C C . LYS A 1 199 ? 80.752 23.672 14.921 1.00 41.44 ? 414 LYS A C 1 ATOM 1421 O O . LYS A 1 199 ? 81.147 22.511 14.840 1.00 41.98 ? 414 LYS A O 1 ATOM 1422 C CB . LYS A 1 199 ? 78.924 24.432 13.388 1.00 42.61 ? 414 LYS A CB 1 ATOM 1423 C CG . LYS A 1 199 ? 79.556 23.644 12.259 1.00 42.36 ? 414 LYS A CG 1 ATOM 1424 C CD . LYS A 1 199 ? 79.068 24.207 10.923 1.00 44.12 ? 414 LYS A CD 1 ATOM 1425 C CE . LYS A 1 199 ? 80.067 23.947 9.817 1.00 47.03 ? 414 LYS A CE 1 ATOM 1426 N NZ . LYS A 1 199 ? 80.599 22.553 9.907 1.00 49.61 ? 414 LYS A NZ 1 ATOM 1427 N N . SER A 1 200 ? 81.575 24.704 15.117 1.00 42.26 ? 415 SER A N 1 ATOM 1428 C CA . SER A 1 200 ? 83.027 24.527 15.207 1.00 41.13 ? 415 SER A CA 1 ATOM 1429 C C . SER A 1 200 ? 83.471 23.670 16.380 1.00 40.90 ? 415 SER A C 1 ATOM 1430 O O . SER A 1 200 ? 84.345 22.820 16.225 1.00 40.38 ? 415 SER A O 1 ATOM 1431 C CB . SER A 1 200 ? 83.723 25.883 15.251 1.00 40.46 ? 415 SER A CB 1 ATOM 1432 O OG . SER A 1 200 ? 83.057 26.763 16.135 1.00 44.25 ? 415 SER A OG 1 ATOM 1433 N N . ARG A 1 201 ? 82.876 23.877 17.552 1.00 41.51 ? 416 ARG A N 1 ATOM 1434 C CA . ARG A 1 201 ? 83.241 23.070 18.718 1.00 41.65 ? 416 ARG A CA 1 ATOM 1435 C C . ARG A 1 201 ? 83.035 21.596 18.358 1.00 41.07 ? 416 ARG A C 1 ATOM 1436 O O . ARG A 1 201 ? 83.859 20.745 18.670 1.00 39.64 ? 416 ARG A O 1 ATOM 1437 C CB . ARG A 1 201 ? 82.372 23.423 19.933 1.00 41.93 ? 416 ARG A CB 1 ATOM 1438 C CG . ARG A 1 201 ? 82.470 24.870 20.420 1.00 41.38 ? 416 ARG A CG 1 ATOM 1439 C CD . ARG A 1 201 ? 81.690 25.064 21.714 1.00 39.12 ? 416 ARG A CD 1 ATOM 1440 N NE . ARG A 1 201 ? 82.259 24.229 22.763 1.00 40.69 ? 416 ARG A NE 1 ATOM 1441 C CZ . ARG A 1 201 ? 81.629 23.867 23.879 1.00 43.95 ? 416 ARG A CZ 1 ATOM 1442 N NH1 . ARG A 1 201 ? 80.381 24.267 24.121 1.00 41.08 ? 416 ARG A NH1 1 ATOM 1443 N NH2 . ARG A 1 201 ? 82.250 23.073 24.751 1.00 45.81 ? 416 ARG A NH2 1 ATOM 1444 N N . TRP A 1 202 ? 81.927 21.303 17.688 1.00 41.50 ? 417 TRP A N 1 ATOM 1445 C CA . TRP A 1 202 ? 81.639 19.935 17.293 1.00 41.77 ? 417 TRP A CA 1 ATOM 1446 C C . TRP A 1 202 ? 82.704 19.398 16.324 1.00 43.80 ? 417 TRP A C 1 ATOM 1447 O O . TRP A 1 202 ? 83.358 18.390 16.599 1.00 43.06 ? 417 TRP A O 1 ATOM 1448 C CB . TRP A 1 202 ? 80.229 19.848 16.676 1.00 37.93 ? 417 TRP A CB 1 ATOM 1449 C CG . TRP A 1 202 ? 79.868 18.472 16.181 1.00 36.20 ? 417 TRP A CG 1 ATOM 1450 C CD1 . TRP A 1 202 ? 79.753 18.073 14.883 1.00 35.55 ? 417 TRP A CD1 1 ATOM 1451 C CD2 . TRP A 1 202 ? 79.678 17.295 16.975 1.00 34.76 ? 417 TRP A CD2 1 ATOM 1452 N NE1 . TRP A 1 202 ? 79.512 16.721 14.815 1.00 33.91 ? 417 TRP A NE1 1 ATOM 1453 C CE2 . TRP A 1 202 ? 79.463 16.221 16.087 1.00 34.11 ? 417 TRP A CE2 1 ATOM 1454 C CE3 . TRP A 1 202 ? 79.673 17.045 18.351 1.00 34.87 ? 417 TRP A CE3 1 ATOM 1455 C CZ2 . TRP A 1 202 ? 79.249 14.918 16.529 1.00 34.85 ? 417 TRP A CZ2 1 ATOM 1456 C CZ3 . TRP A 1 202 ? 79.459 15.743 18.793 1.00 33.81 ? 417 TRP A CZ3 1 ATOM 1457 C CH2 . TRP A 1 202 ? 79.251 14.699 17.884 1.00 35.80 ? 417 TRP A CH2 1 ATOM 1458 N N . GLN A 1 203 ? 82.905 20.075 15.201 1.00 46.97 ? 418 GLN A N 1 ATOM 1459 C CA . GLN A 1 203 ? 83.887 19.594 14.236 1.00 51.65 ? 418 GLN A CA 1 ATOM 1460 C C . GLN A 1 203 ? 85.324 19.424 14.760 1.00 51.51 ? 418 GLN A C 1 ATOM 1461 O O . GLN A 1 203 ? 86.061 18.566 14.285 1.00 49.54 ? 418 GLN A O 1 ATOM 1462 C CB . GLN A 1 203 ? 83.879 20.485 12.988 1.00 54.62 ? 418 GLN A CB 1 ATOM 1463 C CG . GLN A 1 203 ? 82.654 20.268 12.084 1.00 59.78 ? 418 GLN A CG 1 ATOM 1464 C CD . GLN A 1 203 ? 83.012 20.082 10.606 1.00 62.46 ? 418 GLN A CD 1 ATOM 1465 O OE1 . GLN A 1 203 ? 82.134 19.864 9.764 1.00 64.16 ? 418 GLN A OE1 1 ATOM 1466 N NE2 . GLN A 1 203 ? 84.304 20.169 10.288 1.00 63.42 ? 418 GLN A NE2 1 ATOM 1467 N N . GLN A 1 204 ? 85.719 20.232 15.738 1.00 53.48 ? 419 GLN A N 1 ATOM 1468 C CA . GLN A 1 204 ? 87.064 20.132 16.289 1.00 54.61 ? 419 GLN A CA 1 ATOM 1469 C C . GLN A 1 204 ? 87.308 18.746 16.830 1.00 54.23 ? 419 GLN A C 1 ATOM 1470 O O . GLN A 1 204 ? 88.219 18.056 16.389 1.00 57.41 ? 419 GLN A O 1 ATOM 1471 C CB . GLN A 1 204 ? 87.281 21.149 17.401 1.00 56.40 ? 419 GLN A CB 1 ATOM 1472 C CG . GLN A 1 204 ? 87.409 22.575 16.914 1.00 60.90 ? 419 GLN A CG 1 ATOM 1473 C CD . GLN A 1 204 ? 87.883 23.505 18.015 1.00 66.26 ? 419 GLN A CD 1 ATOM 1474 O OE1 . GLN A 1 204 ? 88.944 23.285 18.614 1.00 68.37 ? 419 GLN A OE1 1 ATOM 1475 N NE2 . GLN A 1 204 ? 87.102 24.548 18.295 1.00 68.18 ? 419 GLN A NE2 1 ATOM 1476 N N . GLY A 1 205 ? 86.493 18.334 17.789 1.00 53.12 ? 420 GLY A N 1 ATOM 1477 C CA . GLY A 1 205 ? 86.652 17.009 18.354 1.00 51.59 ? 420 GLY A CA 1 ATOM 1478 C C . GLY A 1 205 ? 86.277 16.973 19.814 1.00 50.49 ? 420 GLY A C 1 ATOM 1479 O O . GLY A 1 205 ? 86.450 15.963 20.490 1.00 50.44 ? 420 GLY A O 1 ATOM 1480 N N . ASN A 1 206 ? 85.753 18.083 20.307 1.00 49.69 ? 421 ASN A N 1 ATOM 1481 C CA . ASN A 1 206 ? 85.374 18.160 21.701 1.00 49.13 ? 421 ASN A CA 1 ATOM 1482 C C . ASN A 1 206 ? 84.461 17.009 22.055 1.00 47.87 ? 421 ASN A C 1 ATOM 1483 O O . ASN A 1 206 ? 83.770 16.462 21.192 1.00 50.66 ? 421 ASN A O 1 ATOM 1484 C CB . ASN A 1 206 ? 84.696 19.497 21.987 1.00 51.56 ? 421 ASN A CB 1 ATOM 1485 C CG . ASN A 1 206 ? 85.621 20.664 21.743 1.00 53.61 ? 421 ASN A CG 1 ATOM 1486 O OD1 . ASN A 1 206 ? 86.752 20.673 22.225 1.00 54.19 ? 421 ASN A OD1 1 ATOM 1487 N ND2 . ASN A 1 206 ? 85.153 21.654 20.989 1.00 56.50 ? 421 ASN A ND2 1 ATOM 1488 N N . VAL A 1 207 ? 84.474 16.637 23.327 1.00 43.37 ? 422 VAL A N 1 ATOM 1489 C CA . VAL A 1 207 ? 83.664 15.541 23.815 1.00 37.74 ? 422 VAL A CA 1 ATOM 1490 C C . VAL A 1 207 ? 82.611 16.046 24.758 1.00 38.35 ? 422 VAL A C 1 ATOM 1491 O O . VAL A 1 207 ? 82.934 16.527 25.843 1.00 40.07 ? 422 VAL A O 1 ATOM 1492 C CB . VAL A 1 207 ? 84.507 14.545 24.580 1.00 33.84 ? 422 VAL A CB 1 ATOM 1493 C CG1 . VAL A 1 207 ? 83.630 13.727 25.477 1.00 32.19 ? 422 VAL A CG1 1 ATOM 1494 C CG2 . VAL A 1 207 ? 85.264 13.662 23.619 1.00 32.19 ? 422 VAL A CG2 1 ATOM 1495 N N . PHE A 1 208 ? 81.351 15.926 24.364 1.00 38.06 ? 423 PHE A N 1 ATOM 1496 C CA . PHE A 1 208 ? 80.266 16.372 25.230 1.00 37.83 ? 423 PHE A CA 1 ATOM 1497 C C . PHE A 1 208 ? 79.639 15.211 25.982 1.00 38.36 ? 423 PHE A C 1 ATOM 1498 O O . PHE A 1 208 ? 79.681 14.066 25.533 1.00 39.38 ? 423 PHE A O 1 ATOM 1499 C CB . PHE A 1 208 ? 79.215 17.093 24.417 1.00 37.49 ? 423 PHE A CB 1 ATOM 1500 C CG . PHE A 1 208 ? 79.759 18.243 23.637 1.00 36.81 ? 423 PHE A CG 1 ATOM 1501 C CD1 . PHE A 1 208 ? 80.537 18.020 22.506 1.00 35.86 ? 423 PHE A CD1 1 ATOM 1502 C CD2 . PHE A 1 208 ? 79.497 19.544 24.031 1.00 33.53 ? 423 PHE A CD2 1 ATOM 1503 C CE1 . PHE A 1 208 ? 81.037 19.069 21.783 1.00 35.35 ? 423 PHE A CE1 1 ATOM 1504 C CE2 . PHE A 1 208 ? 79.990 20.601 23.319 1.00 34.32 ? 423 PHE A CE2 1 ATOM 1505 C CZ . PHE A 1 208 ? 80.764 20.370 22.188 1.00 36.87 ? 423 PHE A CZ 1 ATOM 1506 N N . SER A 1 209 ? 79.059 15.499 27.135 1.00 37.63 ? 424 SER A N 1 ATOM 1507 C CA . SER A 1 209 ? 78.471 14.441 27.920 1.00 39.65 ? 424 SER A CA 1 ATOM 1508 C C . SER A 1 209 ? 77.046 14.658 28.307 1.00 39.47 ? 424 SER A C 1 ATOM 1509 O O . SER A 1 209 ? 76.619 15.782 28.518 1.00 43.17 ? 424 SER A O 1 ATOM 1510 C CB . SER A 1 209 ? 79.293 14.206 29.177 1.00 40.91 ? 424 SER A CB 1 ATOM 1511 O OG . SER A 1 209 ? 80.323 13.272 28.905 1.00 45.12 ? 424 SER A OG 1 ATOM 1512 N N . CYS A 1 210 ? 76.310 13.562 28.406 1.00 37.96 ? 425 CYS A N 1 ATOM 1513 C CA . CYS A 1 210 ? 74.920 13.623 28.800 1.00 38.39 ? 425 CYS A CA 1 ATOM 1514 C C . CYS A 1 210 ? 74.868 12.979 30.170 1.00 37.42 ? 425 CYS A C 1 ATOM 1515 O O . CYS A 1 210 ? 75.134 11.794 30.302 1.00 40.80 ? 425 CYS A O 1 ATOM 1516 C CB . CYS A 1 210 ? 74.064 12.843 27.807 1.00 39.76 ? 425 CYS A CB 1 ATOM 1517 S SG . CYS A 1 210 ? 72.292 12.897 28.187 1.00 44.73 ? 425 CYS A SG 1 ATOM 1518 N N . SER A 1 211 ? 74.565 13.756 31.199 1.00 36.32 ? 426 SER A N 1 ATOM 1519 C CA . SER A 1 211 ? 74.499 13.218 32.559 1.00 34.83 ? 426 SER A CA 1 ATOM 1520 C C . SER A 1 211 ? 73.059 13.000 32.972 1.00 33.77 ? 426 SER A C 1 ATOM 1521 O O . SER A 1 211 ? 72.252 13.927 32.928 1.00 34.69 ? 426 SER A O 1 ATOM 1522 C CB . SER A 1 211 ? 75.161 14.176 33.536 1.00 35.83 ? 426 SER A CB 1 ATOM 1523 O OG . SER A 1 211 ? 76.566 14.094 33.417 1.00 41.85 ? 426 SER A OG 1 ATOM 1524 N N . VAL A 1 212 ? 72.733 11.784 33.383 1.00 30.30 ? 427 VAL A N 1 ATOM 1525 C CA . VAL A 1 212 ? 71.370 11.496 33.765 1.00 29.40 ? 427 VAL A CA 1 ATOM 1526 C C . VAL A 1 212 ? 71.292 10.990 35.163 1.00 30.05 ? 427 VAL A C 1 ATOM 1527 O O . VAL A 1 212 ? 72.123 10.205 35.572 1.00 33.54 ? 427 VAL A O 1 ATOM 1528 C CB . VAL A 1 212 ? 70.760 10.433 32.874 1.00 29.05 ? 427 VAL A CB 1 ATOM 1529 C CG1 . VAL A 1 212 ? 69.289 10.290 33.184 1.00 26.80 ? 427 VAL A CG1 1 ATOM 1530 C CG2 . VAL A 1 212 ? 70.982 10.798 31.418 1.00 31.01 ? 427 VAL A CG2 1 ATOM 1531 N N . MET A 1 213 ? 70.273 11.424 35.887 1.00 31.04 ? 428 MET A N 1 ATOM 1532 C CA . MET A 1 213 ? 70.065 10.993 37.256 1.00 32.77 ? 428 MET A CA 1 ATOM 1533 C C . MET A 1 213 ? 68.675 10.387 37.452 1.00 32.59 ? 428 MET A C 1 ATOM 1534 O O . MET A 1 213 ? 67.662 11.070 37.321 1.00 31.94 ? 428 MET A O 1 ATOM 1535 C CB . MET A 1 213 ? 70.262 12.176 38.196 1.00 35.97 ? 428 MET A CB 1 ATOM 1536 C CG . MET A 1 213 ? 71.724 12.542 38.398 1.00 43.04 ? 428 MET A CG 1 ATOM 1537 S SD . MET A 1 213 ? 72.005 14.041 39.385 1.00 51.20 ? 428 MET A SD 1 ATOM 1538 C CE . MET A 1 213 ? 72.404 15.228 37.973 1.00 48.09 ? 428 MET A CE 1 ATOM 1539 N N . HIS A 1 214 ? 68.634 9.095 37.750 1.00 31.49 ? 429 HIS A N 1 ATOM 1540 C CA . HIS A 1 214 ? 67.371 8.403 37.981 1.00 32.21 ? 429 HIS A CA 1 ATOM 1541 C C . HIS A 1 214 ? 67.586 7.370 39.065 1.00 33.66 ? 429 HIS A C 1 ATOM 1542 O O . HIS A 1 214 ? 68.618 6.720 39.100 1.00 36.99 ? 429 HIS A O 1 ATOM 1543 C CB . HIS A 1 214 ? 66.896 7.710 36.709 1.00 30.05 ? 429 HIS A CB 1 ATOM 1544 C CG . HIS A 1 214 ? 65.485 7.210 36.784 1.00 27.76 ? 429 HIS A CG 1 ATOM 1545 N ND1 . HIS A 1 214 ? 65.172 5.888 37.010 1.00 26.65 ? 429 HIS A ND1 1 ATOM 1546 C CD2 . HIS A 1 214 ? 64.303 7.857 36.652 1.00 25.68 ? 429 HIS A CD2 1 ATOM 1547 C CE1 . HIS A 1 214 ? 63.861 5.742 37.010 1.00 25.37 ? 429 HIS A CE1 1 ATOM 1548 N NE2 . HIS A 1 214 ? 63.310 6.922 36.795 1.00 23.80 ? 429 HIS A NE2 1 ATOM 1549 N N . GLU A 1 215 ? 66.623 7.199 39.952 1.00 33.86 ? 430 GLU A N 1 ATOM 1550 C CA . GLU A 1 215 ? 66.805 6.232 41.012 1.00 34.84 ? 430 GLU A CA 1 ATOM 1551 C C . GLU A 1 215 ? 67.238 4.874 40.485 1.00 35.59 ? 430 GLU A C 1 ATOM 1552 O O . GLU A 1 215 ? 68.229 4.318 40.940 1.00 37.53 ? 430 GLU A O 1 ATOM 1553 C CB . GLU A 1 215 ? 65.520 6.073 41.810 1.00 36.86 ? 430 GLU A CB 1 ATOM 1554 C CG . GLU A 1 215 ? 64.435 5.271 41.143 1.00 40.39 ? 430 GLU A CG 1 ATOM 1555 C CD . GLU A 1 215 ? 63.242 5.094 42.059 1.00 45.84 ? 430 GLU A CD 1 ATOM 1556 O OE1 . GLU A 1 215 ? 62.345 5.971 42.073 1.00 45.25 ? 430 GLU A OE1 1 ATOM 1557 O OE2 . GLU A 1 215 ? 63.216 4.078 42.790 1.00 49.97 ? 430 GLU A OE2 1 ATOM 1558 N N . ALA A 1 216 ? 66.500 4.355 39.508 1.00 35.13 ? 431 ALA A N 1 ATOM 1559 C CA . ALA A 1 216 ? 66.762 3.044 38.930 1.00 31.41 ? 431 ALA A CA 1 ATOM 1560 C C . ALA A 1 216 ? 68.167 2.858 38.424 1.00 30.15 ? 431 ALA A C 1 ATOM 1561 O O . ALA A 1 216 ? 68.652 1.732 38.343 1.00 32.78 ? 431 ALA A O 1 ATOM 1562 C CB . ALA A 1 216 ? 65.765 2.758 37.814 1.00 32.19 ? 431 ALA A CB 1 ATOM 1563 N N . LEU A 1 217 ? 68.830 3.944 38.060 1.00 28.89 ? 432 LEU A N 1 ATOM 1564 C CA . LEU A 1 217 ? 70.203 3.823 37.583 1.00 27.96 ? 432 LEU A CA 1 ATOM 1565 C C . LEU A 1 217 ? 71.144 3.401 38.711 1.00 29.10 ? 432 LEU A C 1 ATOM 1566 O O . LEU A 1 217 ? 70.755 3.349 39.890 1.00 28.08 ? 432 LEU A O 1 ATOM 1567 C CB . LEU A 1 217 ? 70.661 5.140 36.981 1.00 26.38 ? 432 LEU A CB 1 ATOM 1568 C CG . LEU A 1 217 ? 70.070 5.435 35.608 1.00 25.42 ? 432 LEU A CG 1 ATOM 1569 C CD1 . LEU A 1 217 ? 70.090 6.916 35.385 1.00 27.49 ? 432 LEU A CD1 1 ATOM 1570 C CD2 . LEU A 1 217 ? 70.853 4.706 34.523 1.00 22.97 ? 432 LEU A CD2 1 ATOM 1571 N N . HIS A 1 218 ? 72.382 3.080 38.354 1.00 30.14 ? 433 HIS A N 1 ATOM 1572 C CA . HIS A 1 218 ? 73.345 2.650 39.358 1.00 31.09 ? 433 HIS A CA 1 ATOM 1573 C C . HIS A 1 218 ? 73.879 3.857 40.050 1.00 31.74 ? 433 HIS A C 1 ATOM 1574 O O . HIS A 1 218 ? 74.421 4.753 39.411 1.00 33.66 ? 433 HIS A O 1 ATOM 1575 C CB . HIS A 1 218 ? 74.484 1.871 38.725 1.00 30.59 ? 433 HIS A CB 1 ATOM 1576 C CG . HIS A 1 218 ? 74.030 0.647 38.005 1.00 31.96 ? 433 HIS A CG 1 ATOM 1577 N ND1 . HIS A 1 218 ? 74.816 -0.007 37.083 1.00 32.51 ? 433 HIS A ND1 1 ATOM 1578 C CD2 . HIS A 1 218 ? 72.848 -0.013 38.037 1.00 30.06 ? 433 HIS A CD2 1 ATOM 1579 C CE1 . HIS A 1 218 ? 74.133 -1.017 36.572 1.00 34.26 ? 433 HIS A CE1 1 ATOM 1580 N NE2 . HIS A 1 218 ? 72.937 -1.041 37.133 1.00 32.16 ? 433 HIS A NE2 1 ATOM 1581 N N . ASN A 1 219 ? 73.715 3.882 41.364 1.00 32.48 ? 434 ASN A N 1 ATOM 1582 C CA . ASN A 1 219 ? 74.173 5.005 42.153 1.00 34.35 ? 434 ASN A CA 1 ATOM 1583 C C . ASN A 1 219 ? 73.317 6.191 41.738 1.00 34.41 ? 434 ASN A C 1 ATOM 1584 O O . ASN A 1 219 ? 73.671 7.332 41.985 1.00 34.89 ? 434 ASN A O 1 ATOM 1585 C CB . ASN A 1 219 ? 75.648 5.265 41.866 1.00 37.57 ? 434 ASN A CB 1 ATOM 1586 C CG . ASN A 1 219 ? 76.319 6.082 42.939 1.00 40.15 ? 434 ASN A CG 1 ATOM 1587 O OD1 . ASN A 1 219 ? 75.893 6.087 44.094 1.00 41.86 ? 434 ASN A OD1 1 ATOM 1588 N ND2 . ASN A 1 219 ? 77.397 6.763 42.567 1.00 42.94 ? 434 ASN A ND2 1 ATOM 1589 N N . HIS A 1 220 ? 72.189 5.895 41.092 1.00 34.25 ? 435 HIS A N 1 ATOM 1590 C CA . HIS A 1 220 ? 71.249 6.912 40.649 1.00 32.97 ? 435 HIS A CA 1 ATOM 1591 C C . HIS A 1 220 ? 71.795 7.809 39.555 1.00 32.61 ? 435 HIS A C 1 ATOM 1592 O O . HIS A 1 220 ? 71.206 8.845 39.233 1.00 31.60 ? 435 HIS A O 1 ATOM 1593 C CB . HIS A 1 220 ? 70.875 7.786 41.825 1.00 35.41 ? 435 HIS A CB 1 ATOM 1594 C CG . HIS A 1 220 ? 70.316 7.028 42.982 1.00 37.95 ? 435 HIS A CG 1 ATOM 1595 N ND1 . HIS A 1 220 ? 69.277 6.134 42.848 1.00 39.54 ? 435 HIS A ND1 1 ATOM 1596 C CD2 . HIS A 1 220 ? 70.606 7.079 44.302 1.00 38.90 ? 435 HIS A CD2 1 ATOM 1597 C CE1 . HIS A 1 220 ? 68.949 5.669 44.040 1.00 40.81 ? 435 HIS A CE1 1 ATOM 1598 N NE2 . HIS A 1 220 ? 69.739 6.227 44.940 1.00 41.08 ? 435 HIS A NE2 1 ATOM 1599 N N . TYR A 1 221 ? 72.915 7.408 38.976 1.00 30.16 ? 436 TYR A N 1 ATOM 1600 C CA . TYR A 1 221 ? 73.538 8.227 37.969 1.00 28.72 ? 436 TYR A CA 1 ATOM 1601 C C . TYR A 1 221 ? 74.165 7.444 36.857 1.00 30.45 ? 436 TYR A C 1 ATOM 1602 O O . TYR A 1 221 ? 74.588 6.302 37.033 1.00 33.21 ? 436 TYR A O 1 ATOM 1603 C CB . TYR A 1 221 ? 74.608 9.081 38.641 1.00 25.85 ? 436 TYR A CB 1 ATOM 1604 C CG . TYR A 1 221 ? 75.467 9.933 37.728 1.00 25.39 ? 436 TYR A CG 1 ATOM 1605 C CD1 . TYR A 1 221 ? 76.588 9.406 37.089 1.00 23.70 ? 436 TYR A CD1 1 ATOM 1606 C CD2 . TYR A 1 221 ? 75.188 11.286 37.554 1.00 25.06 ? 436 TYR A CD2 1 ATOM 1607 C CE1 . TYR A 1 221 ? 77.411 10.207 36.315 1.00 25.24 ? 436 TYR A CE1 1 ATOM 1608 C CE2 . TYR A 1 221 ? 76.001 12.094 36.781 1.00 24.93 ? 436 TYR A CE2 1 ATOM 1609 C CZ . TYR A 1 221 ? 77.114 11.554 36.167 1.00 26.03 ? 436 TYR A CZ 1 ATOM 1610 O OH . TYR A 1 221 ? 77.936 12.380 35.430 1.00 27.99 ? 436 TYR A OH 1 ATOM 1611 N N . THR A 1 222 ? 74.212 8.064 35.694 1.00 29.62 ? 437 THR A N 1 ATOM 1612 C CA . THR A 1 222 ? 74.878 7.456 34.579 1.00 30.98 ? 437 THR A CA 1 ATOM 1613 C C . THR A 1 222 ? 75.164 8.552 33.597 1.00 32.53 ? 437 THR A C 1 ATOM 1614 O O . THR A 1 222 ? 74.520 9.601 33.606 1.00 33.48 ? 437 THR A O 1 ATOM 1615 C CB . THR A 1 222 ? 74.080 6.348 33.913 1.00 31.36 ? 437 THR A CB 1 ATOM 1616 O OG1 . THR A 1 222 ? 75.000 5.489 33.225 1.00 28.74 ? 437 THR A OG1 1 ATOM 1617 C CG2 . THR A 1 222 ? 73.080 6.924 32.901 1.00 32.81 ? 437 THR A CG2 1 ATOM 1618 N N . GLN A 1 223 ? 76.142 8.291 32.747 1.00 33.91 ? 438 GLN A N 1 ATOM 1619 C CA . GLN A 1 223 ? 76.594 9.263 31.790 1.00 33.48 ? 438 GLN A CA 1 ATOM 1620 C C . GLN A 1 223 ? 76.982 8.594 30.492 1.00 32.46 ? 438 GLN A C 1 ATOM 1621 O O . GLN A 1 223 ? 77.573 7.511 30.481 1.00 30.49 ? 438 GLN A O 1 ATOM 1622 C CB . GLN A 1 223 ? 77.794 9.991 32.381 1.00 36.08 ? 438 GLN A CB 1 ATOM 1623 C CG . GLN A 1 223 ? 78.288 11.140 31.545 1.00 41.00 ? 438 GLN A CG 1 ATOM 1624 C CD . GLN A 1 223 ? 79.453 11.846 32.184 1.00 39.78 ? 438 GLN A CD 1 ATOM 1625 O OE1 . GLN A 1 223 ? 80.562 11.306 32.249 1.00 39.17 ? 438 GLN A OE1 1 ATOM 1626 N NE2 . GLN A 1 223 ? 79.208 13.056 32.676 1.00 36.00 ? 438 GLN A NE2 1 ATOM 1627 N N . LYS A 1 224 ? 76.646 9.264 29.400 1.00 30.82 ? 439 LYS A N 1 ATOM 1628 C CA . LYS A 1 224 ? 76.928 8.771 28.069 1.00 30.63 ? 439 LYS A CA 1 ATOM 1629 C C . LYS A 1 224 ? 77.589 9.939 27.351 1.00 31.26 ? 439 LYS A C 1 ATOM 1630 O O . LYS A 1 224 ? 77.118 11.072 27.446 1.00 31.12 ? 439 LYS A O 1 ATOM 1631 C CB . LYS A 1 224 ? 75.610 8.381 27.396 1.00 29.58 ? 439 LYS A CB 1 ATOM 1632 C CG . LYS A 1 224 ? 75.733 7.454 26.206 1.00 30.38 ? 439 LYS A CG 1 ATOM 1633 C CD . LYS A 1 224 ? 76.242 6.086 26.609 1.00 31.88 ? 439 LYS A CD 1 ATOM 1634 C CE . LYS A 1 224 ? 76.249 5.113 25.436 1.00 32.96 ? 439 LYS A CE 1 ATOM 1635 N NZ . LYS A 1 224 ? 74.874 4.894 24.896 1.00 35.96 ? 439 LYS A NZ 1 ATOM 1636 N N . SER A 1 225 ? 78.695 9.670 26.666 1.00 32.02 ? 440 SER A N 1 ATOM 1637 C CA . SER A 1 225 ? 79.423 10.709 25.947 1.00 32.08 ? 440 SER A CA 1 ATOM 1638 C C . SER A 1 225 ? 79.296 10.581 24.439 1.00 32.97 ? 440 SER A C 1 ATOM 1639 O O . SER A 1 225 ? 79.303 9.484 23.877 1.00 30.19 ? 440 SER A O 1 ATOM 1640 C CB . SER A 1 225 ? 80.903 10.693 26.335 1.00 33.44 ? 440 SER A CB 1 ATOM 1641 O OG . SER A 1 225 ? 81.086 11.147 27.664 1.00 34.81 ? 440 SER A OG 1 ATOM 1642 N N . LEU A 1 226 ? 79.204 11.737 23.793 1.00 35.13 ? 441 LEU A N 1 ATOM 1643 C CA . LEU A 1 226 ? 79.051 11.848 22.350 1.00 35.72 ? 441 LEU A CA 1 ATOM 1644 C C . LEU A 1 226 ? 80.141 12.758 21.815 1.00 37.56 ? 441 LEU A C 1 ATOM 1645 O O . LEU A 1 226 ? 80.452 13.772 22.434 1.00 39.38 ? 441 LEU A O 1 ATOM 1646 C CB . LEU A 1 226 ? 77.692 12.465 22.050 1.00 32.65 ? 441 LEU A CB 1 ATOM 1647 C CG . LEU A 1 226 ? 77.550 13.032 20.652 1.00 33.20 ? 441 LEU A CG 1 ATOM 1648 C CD1 . LEU A 1 226 ? 77.415 11.909 19.646 1.00 32.74 ? 441 LEU A CD1 1 ATOM 1649 C CD2 . LEU A 1 226 ? 76.341 13.923 20.619 1.00 33.98 ? 441 LEU A CD2 1 ATOM 1650 N N . SER A 1 227 ? 80.725 12.416 20.677 1.00 38.48 ? 442 SER A N 1 ATOM 1651 C CA . SER A 1 227 ? 81.763 13.269 20.117 1.00 42.11 ? 442 SER A CA 1 ATOM 1652 C C . SER A 1 227 ? 82.110 12.809 18.718 1.00 44.96 ? 442 SER A C 1 ATOM 1653 O O . SER A 1 227 ? 81.768 11.692 18.333 1.00 46.10 ? 442 SER A O 1 ATOM 1654 C CB . SER A 1 227 ? 83.017 13.238 20.980 1.00 40.72 ? 442 SER A CB 1 ATOM 1655 O OG . SER A 1 227 ? 83.806 12.113 20.656 1.00 44.14 ? 442 SER A OG 1 ATOM 1656 N N . LEU A 1 228 ? 82.795 13.668 17.966 1.00 47.53 ? 443 LEU A N 1 ATOM 1657 C CA . LEU A 1 228 ? 83.177 13.364 16.589 1.00 50.84 ? 443 LEU A CA 1 ATOM 1658 C C . LEU A 1 228 ? 84.546 12.677 16.554 1.00 54.87 ? 443 LEU A C 1 ATOM 1659 O O . LEU A 1 228 ? 85.588 13.321 16.678 1.00 55.48 ? 443 LEU A O 1 ATOM 1660 C CB . LEU A 1 228 ? 83.180 14.663 15.790 1.00 48.85 ? 443 LEU A CB 1 ATOM 1661 C CG . LEU A 1 228 ? 83.349 14.658 14.275 1.00 47.50 ? 443 LEU A CG 1 ATOM 1662 C CD1 . LEU A 1 228 ? 82.364 13.725 13.620 1.00 44.73 ? 443 LEU A CD1 1 ATOM 1663 C CD2 . LEU A 1 228 ? 83.153 16.083 13.785 1.00 46.54 ? 443 LEU A CD2 1 ATOM 1664 N N . SER A 1 229 ? 84.525 11.357 16.386 1.00 60.22 ? 444 SER A N 1 ATOM 1665 C CA . SER A 1 229 ? 85.741 10.537 16.381 1.00 64.10 ? 444 SER A CA 1 ATOM 1666 C C . SER A 1 229 ? 86.729 10.855 15.263 1.00 65.25 ? 444 SER A C 1 ATOM 1667 O O . SER A 1 229 ? 86.296 11.468 14.263 1.00 66.85 ? 444 SER A O 1 ATOM 1668 C CB . SER A 1 229 ? 85.360 9.046 16.327 1.00 65.77 ? 444 SER A CB 1 ATOM 1669 O OG . SER A 1 229 ? 84.435 8.783 15.278 1.00 67.54 ? 444 SER A OG 1 ATOM 1670 N N . PRO A 1 230 ? 87.916 10.470 15.402 1.00 64.88 ? 445 PRO A N 1 ATOM 1671 N N . PRO B 1 23 ? 32.270 24.531 40.145 1.00 93.04 ? 238 PRO B N 1 ATOM 1672 C CA . PRO B 1 23 ? 32.388 24.185 38.699 1.00 93.98 ? 238 PRO B CA 1 ATOM 1673 C C . PRO B 1 23 ? 33.467 25.040 38.037 1.00 94.49 ? 238 PRO B C 1 ATOM 1674 O O . PRO B 1 23 ? 33.605 26.225 38.338 1.00 95.60 ? 238 PRO B O 1 ATOM 1675 C CB . PRO B 1 23 ? 31.040 24.397 37.994 1.00 92.58 ? 238 PRO B CB 1 ATOM 1676 N N . SER B 1 24 ? 34.238 24.428 37.143 1.00 94.57 ? 239 SER B N 1 ATOM 1677 C CA . SER B 1 24 ? 35.299 25.125 36.417 1.00 94.29 ? 239 SER B CA 1 ATOM 1678 C C . SER B 1 24 ? 35.038 24.978 34.920 1.00 94.29 ? 239 SER B C 1 ATOM 1679 O O . SER B 1 24 ? 34.310 24.073 34.496 1.00 95.00 ? 239 SER B O 1 ATOM 1680 C CB . SER B 1 24 ? 36.669 24.513 36.737 1.00 93.94 ? 239 SER B CB 1 ATOM 1681 O OG . SER B 1 24 ? 36.947 24.547 38.120 1.00 93.01 ? 239 SER B OG 1 ATOM 1682 N N . VAL B 1 25 ? 35.633 25.858 34.118 1.00 92.89 ? 240 VAL B N 1 ATOM 1683 C CA . VAL B 1 25 ? 35.461 25.783 32.669 1.00 90.10 ? 240 VAL B CA 1 ATOM 1684 C C . VAL B 1 25 ? 36.761 25.405 31.968 1.00 87.03 ? 240 VAL B C 1 ATOM 1685 O O . VAL B 1 25 ? 37.856 25.658 32.466 1.00 84.78 ? 240 VAL B O 1 ATOM 1686 C CB . VAL B 1 25 ? 34.931 27.115 32.085 1.00 90.77 ? 240 VAL B CB 1 ATOM 1687 C CG1 . VAL B 1 25 ? 34.906 27.049 30.569 1.00 90.89 ? 240 VAL B CG1 1 ATOM 1688 C CG2 . VAL B 1 25 ? 33.524 27.382 32.606 1.00 91.11 ? 240 VAL B CG2 1 ATOM 1689 N N . PHE B 1 26 ? 36.619 24.779 30.810 1.00 84.90 ? 241 PHE B N 1 ATOM 1690 C CA . PHE B 1 26 ? 37.760 24.354 30.028 1.00 83.74 ? 241 PHE B CA 1 ATOM 1691 C C . PHE B 1 26 ? 37.476 24.522 28.533 1.00 82.22 ? 241 PHE B C 1 ATOM 1692 O O . PHE B 1 26 ? 36.715 23.757 27.943 1.00 83.10 ? 241 PHE B O 1 ATOM 1693 C CB . PHE B 1 26 ? 38.076 22.898 30.350 1.00 85.62 ? 241 PHE B CB 1 ATOM 1694 C CG . PHE B 1 26 ? 38.815 22.700 31.652 1.00 88.03 ? 241 PHE B CG 1 ATOM 1695 C CD1 . PHE B 1 26 ? 40.197 22.886 31.720 1.00 88.78 ? 241 PHE B CD1 1 ATOM 1696 C CD2 . PHE B 1 26 ? 38.142 22.282 32.797 1.00 88.88 ? 241 PHE B CD2 1 ATOM 1697 C CE1 . PHE B 1 26 ? 40.898 22.652 32.907 1.00 88.83 ? 241 PHE B CE1 1 ATOM 1698 C CE2 . PHE B 1 26 ? 38.836 22.046 33.989 1.00 89.84 ? 241 PHE B CE2 1 ATOM 1699 C CZ . PHE B 1 26 ? 40.219 22.231 34.040 1.00 89.07 ? 241 PHE B CZ 1 ATOM 1700 N N . LEU B 1 27 ? 38.084 25.538 27.928 1.00 79.25 ? 242 LEU B N 1 ATOM 1701 C CA . LEU B 1 27 ? 37.908 25.805 26.507 1.00 75.78 ? 242 LEU B CA 1 ATOM 1702 C C . LEU B 1 27 ? 39.124 25.292 25.740 1.00 73.08 ? 242 LEU B C 1 ATOM 1703 O O . LEU B 1 27 ? 40.253 25.725 25.983 1.00 73.01 ? 242 LEU B O 1 ATOM 1704 C CB . LEU B 1 27 ? 37.733 27.306 26.273 1.00 76.47 ? 242 LEU B CB 1 ATOM 1705 C CG . LEU B 1 27 ? 37.805 27.772 24.817 1.00 77.72 ? 242 LEU B CG 1 ATOM 1706 C CD1 . LEU B 1 27 ? 36.840 26.966 23.959 1.00 78.31 ? 242 LEU B CD1 1 ATOM 1707 C CD2 . LEU B 1 27 ? 37.481 29.253 24.739 1.00 77.83 ? 242 LEU B CD2 1 ATOM 1708 N N . PHE B 1 28 ? 38.885 24.373 24.809 1.00 68.93 ? 243 PHE B N 1 ATOM 1709 C CA . PHE B 1 28 ? 39.956 23.777 24.016 1.00 64.72 ? 243 PHE B CA 1 ATOM 1710 C C . PHE B 1 28 ? 39.975 24.208 22.543 1.00 60.78 ? 243 PHE B C 1 ATOM 1711 O O . PHE B 1 28 ? 38.932 24.477 21.945 1.00 60.69 ? 243 PHE B O 1 ATOM 1712 C CB . PHE B 1 28 ? 39.862 22.257 24.114 1.00 64.87 ? 243 PHE B CB 1 ATOM 1713 C CG . PHE B 1 28 ? 40.067 21.725 25.509 1.00 65.28 ? 243 PHE B CG 1 ATOM 1714 C CD1 . PHE B 1 28 ? 41.348 21.491 25.999 1.00 65.34 ? 243 PHE B CD1 1 ATOM 1715 C CD2 . PHE B 1 28 ? 38.978 21.447 26.330 1.00 65.80 ? 243 PHE B CD2 1 ATOM 1716 C CE1 . PHE B 1 28 ? 41.540 20.986 27.283 1.00 65.65 ? 243 PHE B CE1 1 ATOM 1717 C CE2 . PHE B 1 28 ? 39.158 20.941 27.618 1.00 65.61 ? 243 PHE B CE2 1 ATOM 1718 C CZ . PHE B 1 28 ? 40.442 20.709 28.096 1.00 65.56 ? 243 PHE B CZ 1 ATOM 1719 N N . PRO B 1 29 ? 41.176 24.286 21.947 1.00 56.53 ? 244 PRO B N 1 ATOM 1720 C CA . PRO B 1 29 ? 41.380 24.682 20.550 1.00 53.78 ? 244 PRO B CA 1 ATOM 1721 C C . PRO B 1 29 ? 41.346 23.508 19.572 1.00 51.83 ? 244 PRO B C 1 ATOM 1722 O O . PRO B 1 29 ? 41.328 22.349 19.980 1.00 54.15 ? 244 PRO B O 1 ATOM 1723 C CB . PRO B 1 29 ? 42.739 25.351 20.597 1.00 54.20 ? 244 PRO B CB 1 ATOM 1724 C CG . PRO B 1 29 ? 43.470 24.491 21.573 1.00 55.19 ? 244 PRO B CG 1 ATOM 1725 C CD . PRO B 1 29 ? 42.460 24.245 22.671 1.00 55.12 ? 244 PRO B CD 1 ATOM 1726 N N . PRO B 1 30 ? 41.339 23.795 18.263 1.00 48.61 ? 245 PRO B N 1 ATOM 1727 C CA . PRO B 1 30 ? 41.305 22.750 17.235 1.00 46.69 ? 245 PRO B CA 1 ATOM 1728 C C . PRO B 1 30 ? 42.619 21.994 17.012 1.00 46.19 ? 245 PRO B C 1 ATOM 1729 O O . PRO B 1 30 ? 43.717 22.521 17.222 1.00 44.44 ? 245 PRO B O 1 ATOM 1730 C CB . PRO B 1 30 ? 40.868 23.510 15.995 1.00 45.67 ? 245 PRO B CB 1 ATOM 1731 C CG . PRO B 1 30 ? 41.511 24.843 16.195 1.00 46.89 ? 245 PRO B CG 1 ATOM 1732 C CD . PRO B 1 30 ? 41.242 25.132 17.655 1.00 47.53 ? 245 PRO B CD 1 ATOM 1733 N N . LYS B 1 31 ? 42.482 20.744 16.585 1.00 45.87 ? 246 LYS B N 1 ATOM 1734 C CA . LYS B 1 31 ? 43.622 19.880 16.318 1.00 45.56 ? 246 LYS B CA 1 ATOM 1735 C C . LYS B 1 31 ? 44.471 20.476 15.204 1.00 44.90 ? 246 LYS B C 1 ATOM 1736 O O . LYS B 1 31 ? 43.966 20.827 14.148 1.00 45.02 ? 246 LYS B O 1 ATOM 1737 C CB . LYS B 1 31 ? 43.137 18.493 15.886 1.00 46.11 ? 246 LYS B CB 1 ATOM 1738 C CG . LYS B 1 31 ? 42.619 17.616 16.993 1.00 47.32 ? 246 LYS B CG 1 ATOM 1739 C CD . LYS B 1 31 ? 43.771 17.096 17.837 1.00 50.71 ? 246 LYS B CD 1 ATOM 1740 C CE . LYS B 1 31 ? 43.285 16.182 18.964 1.00 51.53 ? 246 LYS B CE 1 ATOM 1741 N NZ . LYS B 1 31 ? 42.423 16.905 19.946 1.00 53.80 ? 246 LYS B NZ 1 ATOM 1742 N N . PRO B 1 32 ? 45.774 20.611 15.427 1.00 44.26 ? 247 PRO B N 1 ATOM 1743 C CA . PRO B 1 32 ? 46.562 21.176 14.340 1.00 45.04 ? 247 PRO B CA 1 ATOM 1744 C C . PRO B 1 32 ? 46.275 20.473 13.014 1.00 47.00 ? 247 PRO B C 1 ATOM 1745 O O . PRO B 1 32 ? 46.036 21.123 12.001 1.00 49.44 ? 247 PRO B O 1 ATOM 1746 C CB . PRO B 1 32 ? 47.986 20.968 14.819 1.00 43.48 ? 247 PRO B CB 1 ATOM 1747 C CG . PRO B 1 32 ? 47.851 21.196 16.276 1.00 43.94 ? 247 PRO B CG 1 ATOM 1748 C CD . PRO B 1 32 ? 46.590 20.441 16.638 1.00 43.13 ? 247 PRO B CD 1 ATOM 1749 N N . LYS B 1 33 ? 46.273 19.147 13.012 1.00 48.06 ? 248 LYS B N 1 ATOM 1750 C CA . LYS B 1 33 ? 46.024 18.425 11.774 1.00 49.50 ? 248 LYS B CA 1 ATOM 1751 C C . LYS B 1 33 ? 44.753 18.939 11.102 1.00 51.05 ? 248 LYS B C 1 ATOM 1752 O O . LYS B 1 33 ? 44.747 19.245 9.914 1.00 52.33 ? 248 LYS B O 1 ATOM 1753 C CB . LYS B 1 33 ? 45.904 16.926 12.051 1.00 49.35 ? 248 LYS B CB 1 ATOM 1754 C CG . LYS B 1 33 ? 46.294 16.024 10.880 1.00 49.97 ? 248 LYS B CG 1 ATOM 1755 C CD . LYS B 1 33 ? 46.206 14.540 11.285 1.00 51.12 ? 248 LYS B CD 1 ATOM 1756 C CE . LYS B 1 33 ? 46.795 13.589 10.233 1.00 49.86 ? 248 LYS B CE 1 ATOM 1757 N NZ . LYS B 1 33 ? 46.110 13.606 8.914 1.00 48.15 ? 248 LYS B NZ 1 ATOM 1758 N N . ASP B 1 34 ? 43.680 19.058 11.869 1.00 52.35 ? 249 ASP B N 1 ATOM 1759 C CA . ASP B 1 34 ? 42.408 19.522 11.323 1.00 53.53 ? 249 ASP B CA 1 ATOM 1760 C C . ASP B 1 34 ? 42.448 20.909 10.675 1.00 54.21 ? 249 ASP B C 1 ATOM 1761 O O . ASP B 1 34 ? 41.896 21.094 9.602 1.00 56.01 ? 249 ASP B O 1 ATOM 1762 C CB . ASP B 1 34 ? 41.336 19.517 12.412 1.00 53.68 ? 249 ASP B CB 1 ATOM 1763 C CG . ASP B 1 34 ? 41.142 18.149 13.046 1.00 53.90 ? 249 ASP B CG 1 ATOM 1764 O OD1 . ASP B 1 34 ? 40.620 18.107 14.181 1.00 54.65 ? 249 ASP B OD1 1 ATOM 1765 O OD2 . ASP B 1 34 ? 41.497 17.124 12.421 1.00 53.41 ? 249 ASP B OD2 1 ATOM 1766 N N . THR B 1 35 ? 43.087 21.887 11.309 1.00 54.08 ? 250 THR B N 1 ATOM 1767 C CA . THR B 1 35 ? 43.125 23.228 10.731 1.00 55.04 ? 250 THR B CA 1 ATOM 1768 C C . THR B 1 35 ? 44.068 23.386 9.549 1.00 56.68 ? 250 THR B C 1 ATOM 1769 O O . THR B 1 35 ? 44.153 24.481 8.993 1.00 57.94 ? 250 THR B O 1 ATOM 1770 C CB . THR B 1 35 ? 43.522 24.307 11.762 1.00 54.38 ? 250 THR B CB 1 ATOM 1771 O OG1 . THR B 1 35 ? 44.906 24.161 12.112 1.00 54.12 ? 250 THR B OG1 1 ATOM 1772 C CG2 . THR B 1 35 ? 42.666 24.192 13.004 1.00 55.03 ? 250 THR B CG2 1 ATOM 1773 N N . LEU B 1 36 ? 44.774 22.319 9.165 1.00 56.74 ? 251 LEU B N 1 ATOM 1774 C CA . LEU B 1 36 ? 45.713 22.392 8.043 1.00 56.74 ? 251 LEU B CA 1 ATOM 1775 C C . LEU B 1 36 ? 45.247 21.657 6.795 1.00 57.80 ? 251 LEU B C 1 ATOM 1776 O O . LEU B 1 36 ? 45.686 21.971 5.692 1.00 59.56 ? 251 LEU B O 1 ATOM 1777 C CB . LEU B 1 36 ? 47.086 21.864 8.454 1.00 56.59 ? 251 LEU B CB 1 ATOM 1778 C CG . LEU B 1 36 ? 47.806 22.617 9.572 1.00 56.16 ? 251 LEU B CG 1 ATOM 1779 C CD1 . LEU B 1 36 ? 49.094 21.905 9.907 1.00 56.50 ? 251 LEU B CD1 1 ATOM 1780 C CD2 . LEU B 1 36 ? 48.083 24.035 9.144 1.00 57.14 ? 251 LEU B CD2 1 ATOM 1781 N N . MET B 1 37 ? 44.386 20.659 6.964 1.00 58.48 ? 252 MET B N 1 ATOM 1782 C CA . MET B 1 37 ? 43.839 19.932 5.822 1.00 59.00 ? 252 MET B CA 1 ATOM 1783 C C . MET B 1 37 ? 42.409 20.445 5.602 1.00 58.72 ? 252 MET B C 1 ATOM 1784 O O . MET B 1 37 ? 41.531 20.268 6.445 1.00 58.36 ? 252 MET B O 1 ATOM 1785 C CB . MET B 1 37 ? 43.822 18.433 6.090 1.00 60.28 ? 252 MET B CB 1 ATOM 1786 C CG . MET B 1 37 ? 45.185 17.831 6.323 1.00 62.97 ? 252 MET B CG 1 ATOM 1787 S SD . MET B 1 37 ? 45.093 16.033 6.318 1.00 66.55 ? 252 MET B SD 1 ATOM 1788 C CE . MET B 1 37 ? 45.195 15.725 4.535 1.00 65.65 ? 252 MET B CE 1 ATOM 1789 N N . ILE B 1 38 ? 42.182 21.081 4.461 1.00 58.35 ? 253 ILE B N 1 ATOM 1790 C CA . ILE B 1 38 ? 40.883 21.663 4.143 1.00 57.73 ? 253 ILE B CA 1 ATOM 1791 C C . ILE B 1 38 ? 39.685 20.710 4.252 1.00 57.26 ? 253 ILE B C 1 ATOM 1792 O O . ILE B 1 38 ? 38.640 21.072 4.798 1.00 55.88 ? 253 ILE B O 1 ATOM 1793 C CB . ILE B 1 38 ? 40.922 22.281 2.734 1.00 57.29 ? 253 ILE B CB 1 ATOM 1794 C CG1 . ILE B 1 38 ? 39.697 23.167 2.520 1.00 57.02 ? 253 ILE B CG1 1 ATOM 1795 C CG2 . ILE B 1 38 ? 41.026 21.184 1.692 1.00 57.89 ? 253 ILE B CG2 1 ATOM 1796 C CD1 . ILE B 1 38 ? 39.660 24.374 3.431 1.00 56.29 ? 253 ILE B CD1 1 ATOM 1797 N N . SER B 1 39 ? 39.842 19.497 3.729 1.00 57.04 ? 254 SER B N 1 ATOM 1798 C CA . SER B 1 39 ? 38.776 18.499 3.762 1.00 56.30 ? 254 SER B CA 1 ATOM 1799 C C . SER B 1 39 ? 38.280 18.310 5.181 1.00 57.30 ? 254 SER B C 1 ATOM 1800 O O . SER B 1 39 ? 37.077 18.233 5.433 1.00 56.46 ? 254 SER B O 1 ATOM 1801 C CB . SER B 1 39 ? 39.297 17.167 3.249 1.00 54.37 ? 254 SER B CB 1 ATOM 1802 O OG . SER B 1 39 ? 40.287 16.670 4.124 1.00 52.01 ? 254 SER B OG 1 ATOM 1803 N N . ARG B 1 40 ? 39.235 18.227 6.101 1.00 59.16 ? 255 ARG B N 1 ATOM 1804 C CA . ARG B 1 40 ? 38.946 18.032 7.514 1.00 59.68 ? 255 ARG B CA 1 ATOM 1805 C C . ARG B 1 40 ? 38.213 19.240 8.063 1.00 59.36 ? 255 ARG B C 1 ATOM 1806 O O . ARG B 1 40 ? 38.250 20.322 7.475 1.00 56.99 ? 255 ARG B O 1 ATOM 1807 C CB . ARG B 1 40 ? 40.244 17.802 8.291 1.00 59.62 ? 255 ARG B CB 1 ATOM 1808 C CG . ARG B 1 40 ? 41.129 16.731 7.680 1.00 61.33 ? 255 ARG B CG 1 ATOM 1809 C CD . ARG B 1 40 ? 42.393 16.542 8.495 1.00 64.22 ? 255 ARG B CD 1 ATOM 1810 N NE . ARG B 1 40 ? 42.105 15.926 9.785 1.00 65.14 ? 255 ARG B NE 1 ATOM 1811 C CZ . ARG B 1 40 ? 41.945 14.622 9.967 1.00 63.91 ? 255 ARG B CZ 1 ATOM 1812 N NH1 . ARG B 1 40 ? 42.053 13.796 8.933 1.00 62.31 ? 255 ARG B NH1 1 ATOM 1813 N NH2 . ARG B 1 40 ? 41.669 14.152 11.179 1.00 62.84 ? 255 ARG B NH2 1 ATOM 1814 N N . THR B 1 41 ? 37.554 19.039 9.198 1.00 60.55 ? 256 THR B N 1 ATOM 1815 C CA . THR B 1 41 ? 36.781 20.092 9.830 1.00 62.13 ? 256 THR B CA 1 ATOM 1816 C C . THR B 1 41 ? 37.221 20.408 11.250 1.00 62.70 ? 256 THR B C 1 ATOM 1817 O O . THR B 1 41 ? 36.890 19.688 12.187 1.00 62.52 ? 256 THR B O 1 ATOM 1818 C CB . THR B 1 41 ? 35.284 19.724 9.855 1.00 62.34 ? 256 THR B CB 1 ATOM 1819 O OG1 . THR B 1 41 ? 35.143 18.337 10.184 1.00 64.23 ? 256 THR B OG1 1 ATOM 1820 C CG2 . THR B 1 41 ? 34.641 19.989 8.504 1.00 62.10 ? 256 THR B CG2 1 ATOM 1821 N N . PRO B 1 42 ? 37.976 21.500 11.428 1.00 63.96 ? 257 PRO B N 1 ATOM 1822 C CA . PRO B 1 42 ? 38.440 21.890 12.758 1.00 65.97 ? 257 PRO B CA 1 ATOM 1823 C C . PRO B 1 42 ? 37.252 22.282 13.639 1.00 67.96 ? 257 PRO B C 1 ATOM 1824 O O . PRO B 1 42 ? 36.142 22.445 13.141 1.00 68.74 ? 257 PRO B O 1 ATOM 1825 C CB . PRO B 1 42 ? 39.360 23.073 12.455 1.00 64.47 ? 257 PRO B CB 1 ATOM 1826 C CG . PRO B 1 42 ? 38.732 23.677 11.256 1.00 62.53 ? 257 PRO B CG 1 ATOM 1827 C CD . PRO B 1 42 ? 38.430 22.470 10.417 1.00 63.16 ? 257 PRO B CD 1 ATOM 1828 N N . GLU B 1 43 ? 37.481 22.421 14.941 1.00 70.23 ? 258 GLU B N 1 ATOM 1829 C CA . GLU B 1 43 ? 36.419 22.819 15.857 1.00 73.52 ? 258 GLU B CA 1 ATOM 1830 C C . GLU B 1 43 ? 36.964 23.111 17.255 1.00 75.76 ? 258 GLU B C 1 ATOM 1831 O O . GLU B 1 43 ? 37.905 22.461 17.711 1.00 76.85 ? 258 GLU B O 1 ATOM 1832 C CB . GLU B 1 43 ? 35.336 21.729 15.920 1.00 73.12 ? 258 GLU B CB 1 ATOM 1833 C CG . GLU B 1 43 ? 35.749 20.436 16.625 1.00 74.82 ? 258 GLU B CG 1 ATOM 1834 C CD . GLU B 1 43 ? 34.694 19.326 16.524 1.00 75.57 ? 258 GLU B CD 1 ATOM 1835 O OE1 . GLU B 1 43 ? 34.723 18.389 17.357 1.00 74.45 ? 258 GLU B OE1 1 ATOM 1836 O OE2 . GLU B 1 43 ? 33.842 19.382 15.607 1.00 75.63 ? 258 GLU B OE2 1 ATOM 1837 N N . VAL B 1 44 ? 36.390 24.102 17.928 1.00 78.60 ? 259 VAL B N 1 ATOM 1838 C CA . VAL B 1 44 ? 36.825 24.438 19.281 1.00 82.80 ? 259 VAL B CA 1 ATOM 1839 C C . VAL B 1 44 ? 35.880 23.760 20.274 1.00 84.94 ? 259 VAL B C 1 ATOM 1840 O O . VAL B 1 44 ? 34.668 23.789 20.097 1.00 85.12 ? 259 VAL B O 1 ATOM 1841 C CB . VAL B 1 44 ? 36.816 25.971 19.527 1.00 83.33 ? 259 VAL B CB 1 ATOM 1842 C CG1 . VAL B 1 44 ? 37.663 26.676 18.477 1.00 82.31 ? 259 VAL B CG1 1 ATOM 1843 C CG2 . VAL B 1 44 ? 35.395 26.496 19.499 1.00 84.73 ? 259 VAL B CG2 1 ATOM 1844 N N . THR B 1 45 ? 36.437 23.152 21.316 1.00 88.49 ? 260 THR B N 1 ATOM 1845 C CA . THR B 1 45 ? 35.629 22.451 22.311 1.00 92.71 ? 260 THR B CA 1 ATOM 1846 C C . THR B 1 45 ? 35.581 23.145 23.672 1.00 95.80 ? 260 THR B C 1 ATOM 1847 O O . THR B 1 45 ? 36.607 23.571 24.201 1.00 96.37 ? 260 THR B O 1 ATOM 1848 C CB . THR B 1 45 ? 36.154 21.012 22.515 1.00 93.04 ? 260 THR B CB 1 ATOM 1849 O OG1 . THR B 1 45 ? 36.062 20.292 21.280 1.00 94.50 ? 260 THR B OG1 1 ATOM 1850 C CG2 . THR B 1 45 ? 35.347 20.286 23.573 1.00 93.05 ? 260 THR B CG2 1 ATOM 1851 N N . CYS B 1 46 ? 34.381 23.244 24.237 1.00 99.53 ? 261 CYS B N 1 ATOM 1852 C CA . CYS B 1 46 ? 34.173 23.871 25.543 1.00 102.90 ? 261 CYS B CA 1 ATOM 1853 C C . CYS B 1 46 ? 33.663 22.795 26.499 1.00 102.73 ? 261 CYS B C 1 ATOM 1854 O O . CYS B 1 46 ? 32.776 22.022 26.155 1.00 102.78 ? 261 CYS B O 1 ATOM 1855 C CB . CYS B 1 46 ? 33.140 24.994 25.416 1.00 105.99 ? 261 CYS B CB 1 ATOM 1856 S SG . CYS B 1 46 ? 32.988 26.156 26.816 1.00 110.97 ? 261 CYS B SG 1 ATOM 1857 N N . VAL B 1 47 ? 34.217 22.741 27.700 1.00 103.40 ? 262 VAL B N 1 ATOM 1858 C CA . VAL B 1 47 ? 33.795 21.728 28.653 1.00 105.03 ? 262 VAL B CA 1 ATOM 1859 C C . VAL B 1 47 ? 33.511 22.333 30.027 1.00 106.61 ? 262 VAL B C 1 ATOM 1860 O O . VAL B 1 47 ? 34.003 23.416 30.351 1.00 106.84 ? 262 VAL B O 1 ATOM 1861 C CB . VAL B 1 47 ? 34.883 20.639 28.804 1.00 105.11 ? 262 VAL B CB 1 ATOM 1862 C CG1 . VAL B 1 47 ? 34.277 19.367 29.371 1.00 104.87 ? 262 VAL B CG1 1 ATOM 1863 C CG2 . VAL B 1 47 ? 35.540 20.374 27.467 1.00 104.61 ? 262 VAL B CG2 1 ATOM 1864 N N . VAL B 1 48 ? 32.710 21.627 30.826 1.00 108.26 ? 263 VAL B N 1 ATOM 1865 C CA . VAL B 1 48 ? 32.364 22.070 32.176 1.00 109.18 ? 263 VAL B CA 1 ATOM 1866 C C . VAL B 1 48 ? 32.630 20.930 33.162 1.00 110.41 ? 263 VAL B C 1 ATOM 1867 O O . VAL B 1 48 ? 31.865 19.966 33.228 1.00 110.52 ? 263 VAL B O 1 ATOM 1868 C CB . VAL B 1 48 ? 30.877 22.469 32.282 1.00 108.40 ? 263 VAL B CB 1 ATOM 1869 C CG1 . VAL B 1 48 ? 30.654 23.277 33.552 1.00 107.93 ? 263 VAL B CG1 1 ATOM 1870 C CG2 . VAL B 1 48 ? 30.454 23.257 31.052 1.00 107.93 ? 263 VAL B CG2 1 ATOM 1871 N N . VAL B 1 49 ? 33.723 21.045 33.917 1.00 112.00 ? 264 VAL B N 1 ATOM 1872 C CA . VAL B 1 49 ? 34.120 20.032 34.899 1.00 112.93 ? 264 VAL B CA 1 ATOM 1873 C C . VAL B 1 49 ? 33.510 20.266 36.282 1.00 114.35 ? 264 VAL B C 1 ATOM 1874 O O . VAL B 1 49 ? 33.414 21.400 36.755 1.00 114.14 ? 264 VAL B O 1 ATOM 1875 C CB . VAL B 1 49 ? 35.668 19.965 35.040 1.00 111.93 ? 264 VAL B CB 1 ATOM 1876 C CG1 . VAL B 1 49 ? 36.051 19.203 36.284 1.00 111.25 ? 264 VAL B CG1 1 ATOM 1877 C CG2 . VAL B 1 49 ? 36.266 19.286 33.833 1.00 110.95 ? 264 VAL B CG2 1 ATOM 1878 N N . ASP B 1 50 ? 33.101 19.172 36.920 1.00 116.05 ? 265 ASP B N 1 ATOM 1879 C CA . ASP B 1 50 ? 32.496 19.211 38.246 1.00 117.69 ? 265 ASP B CA 1 ATOM 1880 C C . ASP B 1 50 ? 31.172 19.969 38.277 1.00 119.07 ? 265 ASP B C 1 ATOM 1881 O O . ASP B 1 50 ? 31.099 21.120 38.715 1.00 119.15 ? 265 ASP B O 1 ATOM 1882 C CB . ASP B 1 50 ? 33.483 19.799 39.254 1.00 117.43 ? 265 ASP B CB 1 ATOM 1883 C CG . ASP B 1 50 ? 34.727 18.944 39.402 1.00 117.64 ? 265 ASP B CG 1 ATOM 1884 O OD1 . ASP B 1 50 ? 34.574 17.725 39.623 1.00 117.60 ? 265 ASP B OD1 1 ATOM 1885 O OD2 . ASP B 1 50 ? 35.851 19.481 39.298 1.00 117.56 ? 265 ASP B OD2 1 ATOM 1886 N N . VAL B 1 51 ? 30.130 19.294 37.801 1.00 120.69 ? 266 VAL B N 1 ATOM 1887 C CA . VAL B 1 51 ? 28.780 19.836 37.752 1.00 122.30 ? 266 VAL B CA 1 ATOM 1888 C C . VAL B 1 51 ? 27.824 18.790 38.327 1.00 123.97 ? 266 VAL B C 1 ATOM 1889 O O . VAL B 1 51 ? 27.470 17.824 37.653 1.00 124.37 ? 266 VAL B O 1 ATOM 1890 C CB . VAL B 1 51 ? 28.376 20.166 36.299 1.00 121.73 ? 266 VAL B CB 1 ATOM 1891 C CG1 . VAL B 1 51 ? 26.919 20.596 36.238 1.00 121.89 ? 266 VAL B CG1 1 ATOM 1892 C CG2 . VAL B 1 51 ? 29.274 21.266 35.758 1.00 121.15 ? 266 VAL B CG2 1 ATOM 1893 N N . SER B 1 52 ? 27.420 18.996 39.579 1.00 125.97 ? 267 SER B N 1 ATOM 1894 C CA . SER B 1 52 ? 26.523 18.086 40.294 1.00 127.62 ? 267 SER B CA 1 ATOM 1895 C C . SER B 1 52 ? 25.224 17.768 39.554 1.00 128.98 ? 267 SER B C 1 ATOM 1896 O O . SER B 1 52 ? 24.897 18.400 38.547 1.00 129.30 ? 267 SER B O 1 ATOM 1897 C CB . SER B 1 52 ? 26.182 18.673 41.659 1.00 127.49 ? 267 SER B CB 1 ATOM 1898 O OG . SER B 1 52 ? 25.413 19.855 41.509 1.00 127.41 ? 267 SER B OG 1 ATOM 1899 N N . HIS B 1 53 ? 24.479 16.796 40.081 1.00 130.40 ? 268 HIS B N 1 ATOM 1900 C CA . HIS B 1 53 ? 23.213 16.361 39.486 1.00 131.55 ? 268 HIS B CA 1 ATOM 1901 C C . HIS B 1 53 ? 22.072 17.354 39.707 1.00 132.57 ? 268 HIS B C 1 ATOM 1902 O O . HIS B 1 53 ? 21.092 17.353 38.959 1.00 132.28 ? 268 HIS B O 1 ATOM 1903 C CB . HIS B 1 53 ? 22.785 15.006 40.062 1.00 131.07 ? 268 HIS B CB 1 ATOM 1904 C CG . HIS B 1 53 ? 23.925 14.092 40.392 1.00 130.89 ? 268 HIS B CG 1 ATOM 1905 N ND1 . HIS B 1 53 ? 24.799 14.339 41.429 1.00 130.58 ? 268 HIS B ND1 1 ATOM 1906 C CD2 . HIS B 1 53 ? 24.319 12.920 39.840 1.00 130.68 ? 268 HIS B CD2 1 ATOM 1907 C CE1 . HIS B 1 53 ? 25.679 13.357 41.503 1.00 130.51 ? 268 HIS B CE1 1 ATOM 1908 N NE2 . HIS B 1 53 ? 25.411 12.483 40.550 1.00 130.32 ? 268 HIS B NE2 1 ATOM 1909 N N . GLU B 1 54 ? 22.196 18.185 40.741 1.00 134.07 ? 269 GLU B N 1 ATOM 1910 C CA . GLU B 1 54 ? 21.170 19.175 41.075 1.00 135.05 ? 269 GLU B CA 1 ATOM 1911 C C . GLU B 1 54 ? 20.839 20.077 39.895 1.00 135.76 ? 269 GLU B C 1 ATOM 1912 O O . GLU B 1 54 ? 19.817 19.896 39.230 1.00 135.77 ? 269 GLU B O 1 ATOM 1913 C CB . GLU B 1 54 ? 21.617 20.037 42.264 1.00 134.99 ? 269 GLU B CB 1 ATOM 1914 C CG . GLU B 1 54 ? 21.753 19.282 43.581 1.00 135.47 ? 269 GLU B CG 1 ATOM 1915 C CD . GLU B 1 54 ? 22.980 18.388 43.627 1.00 135.92 ? 269 GLU B CD 1 ATOM 1916 O OE1 . GLU B 1 54 ? 24.102 18.928 43.553 1.00 136.35 ? 269 GLU B OE1 1 ATOM 1917 O OE2 . GLU B 1 54 ? 22.827 17.151 43.740 1.00 135.52 ? 269 GLU B OE2 1 ATOM 1918 N N . GLU B 1 55 ? 21.705 21.055 39.649 1.00 136.59 ? 270 GLU B N 1 ATOM 1919 C CA . GLU B 1 55 ? 21.519 21.989 38.546 1.00 137.39 ? 270 GLU B CA 1 ATOM 1920 C C . GLU B 1 55 ? 22.554 21.732 37.452 1.00 138.23 ? 270 GLU B C 1 ATOM 1921 O O . GLU B 1 55 ? 23.575 22.416 37.371 1.00 138.04 ? 270 GLU B O 1 ATOM 1922 C CB . GLU B 1 55 ? 21.633 23.434 39.049 1.00 136.77 ? 270 GLU B CB 1 ATOM 1923 C CG . GLU B 1 55 ? 20.315 24.203 39.063 1.00 135.79 ? 270 GLU B CG 1 ATOM 1924 C CD . GLU B 1 55 ? 19.254 23.547 39.928 1.00 135.25 ? 270 GLU B CD 1 ATOM 1925 O OE1 . GLU B 1 55 ? 19.446 23.462 41.159 1.00 134.93 ? 270 GLU B OE1 1 ATOM 1926 O OE2 . GLU B 1 55 ? 18.224 23.113 39.373 1.00 134.29 ? 270 GLU B OE2 1 ATOM 1927 N N . PRO B 1 56 ? 22.305 20.723 36.600 1.00 139.33 ? 271 PRO B N 1 ATOM 1928 C CA . PRO B 1 56 ? 23.233 20.397 35.515 1.00 140.03 ? 271 PRO B CA 1 ATOM 1929 C C . PRO B 1 56 ? 22.996 21.295 34.302 1.00 140.42 ? 271 PRO B C 1 ATOM 1930 O O . PRO B 1 56 ? 23.945 21.816 33.714 1.00 140.94 ? 271 PRO B O 1 ATOM 1931 C CB . PRO B 1 56 ? 22.910 18.936 35.226 1.00 140.08 ? 271 PRO B CB 1 ATOM 1932 C CG . PRO B 1 56 ? 21.422 18.912 35.398 1.00 139.89 ? 271 PRO B CG 1 ATOM 1933 C CD . PRO B 1 56 ? 21.210 19.736 36.664 1.00 139.72 ? 271 PRO B CD 1 ATOM 1934 N N . GLU B 1 57 ? 21.722 21.472 33.950 1.00 140.05 ? 272 GLU B N 1 ATOM 1935 C CA . GLU B 1 57 ? 21.303 22.289 32.812 1.00 139.40 ? 272 GLU B CA 1 ATOM 1936 C C . GLU B 1 57 ? 22.157 23.543 32.632 1.00 138.85 ? 272 GLU B C 1 ATOM 1937 O O . GLU B 1 57 ? 22.222 24.398 33.523 1.00 139.06 ? 272 GLU B O 1 ATOM 1938 C CB . GLU B 1 57 ? 19.836 22.675 32.981 1.00 139.82 ? 272 GLU B CB 1 ATOM 1939 C CG . GLU B 1 57 ? 18.940 21.481 33.261 1.00 140.82 ? 272 GLU B CG 1 ATOM 1940 C CD . GLU B 1 57 ? 17.482 21.860 33.402 1.00 141.48 ? 272 GLU B CD 1 ATOM 1941 O OE1 . GLU B 1 57 ? 16.661 20.962 33.696 1.00 141.29 ? 272 GLU B OE1 1 ATOM 1942 O OE2 . GLU B 1 57 ? 17.157 23.054 33.217 1.00 142.02 ? 272 GLU B OE2 1 ATOM 1943 N N . VAL B 1 58 ? 22.799 23.646 31.466 1.00 137.53 ? 273 VAL B N 1 ATOM 1944 C CA . VAL B 1 58 ? 23.678 24.773 31.150 1.00 135.48 ? 273 VAL B CA 1 ATOM 1945 C C . VAL B 1 58 ? 23.283 25.589 29.917 1.00 133.67 ? 273 VAL B C 1 ATOM 1946 O O . VAL B 1 58 ? 22.250 25.345 29.286 1.00 133.16 ? 273 VAL B O 1 ATOM 1947 C CB . VAL B 1 58 ? 25.143 24.298 30.950 1.00 135.54 ? 273 VAL B CB 1 ATOM 1948 C CG1 . VAL B 1 58 ? 25.716 23.795 32.267 1.00 135.54 ? 273 VAL B CG1 1 ATOM 1949 C CG2 . VAL B 1 58 ? 25.197 23.198 29.894 1.00 134.79 ? 273 VAL B CG2 1 ATOM 1950 N N . LYS B 1 59 ? 24.133 26.561 29.593 1.00 131.60 ? 274 LYS B N 1 ATOM 1951 C CA . LYS B 1 59 ? 23.938 27.448 28.450 1.00 129.78 ? 274 LYS B CA 1 ATOM 1952 C C . LYS B 1 59 ? 25.288 27.692 27.773 1.00 128.30 ? 274 LYS B C 1 ATOM 1953 O O . LYS B 1 59 ? 26.328 27.752 28.438 1.00 127.71 ? 274 LYS B O 1 ATOM 1954 C CB . LYS B 1 59 ? 23.346 28.781 28.914 1.00 130.14 ? 274 LYS B CB 1 ATOM 1955 C CG . LYS B 1 59 ? 23.184 29.815 27.817 1.00 130.05 ? 274 LYS B CG 1 ATOM 1956 C CD . LYS B 1 59 ? 22.821 31.165 28.404 1.00 131.03 ? 274 LYS B CD 1 ATOM 1957 C CE . LYS B 1 59 ? 22.612 32.199 27.312 1.00 132.20 ? 274 LYS B CE 1 ATOM 1958 N NZ . LYS B 1 59 ? 22.295 33.548 27.860 1.00 132.95 ? 274 LYS B NZ 1 ATOM 1959 N N . PHE B 1 60 ? 25.263 27.840 26.451 1.00 126.15 ? 275 PHE B N 1 ATOM 1960 C CA . PHE B 1 60 ? 26.479 28.063 25.679 1.00 123.92 ? 275 PHE B CA 1 ATOM 1961 C C . PHE B 1 60 ? 26.325 29.188 24.658 1.00 123.08 ? 275 PHE B C 1 ATOM 1962 O O . PHE B 1 60 ? 25.466 29.133 23.779 1.00 122.97 ? 275 PHE B O 1 ATOM 1963 C CB . PHE B 1 60 ? 26.876 26.764 24.971 1.00 122.92 ? 275 PHE B CB 1 ATOM 1964 C CG . PHE B 1 60 ? 27.327 25.673 25.907 1.00 121.89 ? 275 PHE B CG 1 ATOM 1965 C CD1 . PHE B 1 60 ? 26.919 24.360 25.711 1.00 121.36 ? 275 PHE B CD1 1 ATOM 1966 C CD2 . PHE B 1 60 ? 28.180 25.956 26.971 1.00 121.85 ? 275 PHE B CD2 1 ATOM 1967 C CE1 . PHE B 1 60 ? 27.353 23.343 26.562 1.00 121.76 ? 275 PHE B CE1 1 ATOM 1968 C CE2 . PHE B 1 60 ? 28.620 24.946 27.827 1.00 121.67 ? 275 PHE B CE2 1 ATOM 1969 C CZ . PHE B 1 60 ? 28.206 23.639 27.621 1.00 121.73 ? 275 PHE B CZ 1 ATOM 1970 N N . ASN B 1 61 ? 27.172 30.205 24.779 1.00 122.19 ? 276 ASN B N 1 ATOM 1971 C CA . ASN B 1 61 ? 27.146 31.352 23.879 1.00 121.62 ? 276 ASN B CA 1 ATOM 1972 C C . ASN B 1 61 ? 28.501 31.482 23.198 1.00 121.60 ? 276 ASN B C 1 ATOM 1973 O O . ASN B 1 61 ? 29.518 31.674 23.866 1.00 121.03 ? 276 ASN B O 1 ATOM 1974 C CB . ASN B 1 61 ? 26.850 32.610 24.681 1.00 121.89 ? 276 ASN B CB 1 ATOM 1975 C CG . ASN B 1 61 ? 25.704 32.419 25.637 1.00 122.04 ? 276 ASN B CG 1 ATOM 1976 O OD1 . ASN B 1 61 ? 24.563 32.233 25.220 1.00 122.37 ? 276 ASN B OD1 1 ATOM 1977 N ND2 . ASN B 1 61 ? 26.000 32.447 26.932 1.00 121.96 ? 276 ASN B ND2 1 ATOM 1978 N N . TRP B 1 62 ? 28.517 31.388 21.870 1.00 121.70 ? 277 TRP B N 1 ATOM 1979 C CA . TRP B 1 62 ? 29.773 31.475 21.129 1.00 121.76 ? 277 TRP B CA 1 ATOM 1980 C C . TRP B 1 62 ? 29.911 32.707 20.242 1.00 120.87 ? 277 TRP B C 1 ATOM 1981 O O . TRP B 1 62 ? 29.094 32.939 19.352 1.00 120.33 ? 277 TRP B O 1 ATOM 1982 C CB . TRP B 1 62 ? 29.973 30.221 20.271 1.00 122.93 ? 277 TRP B CB 1 ATOM 1983 C CG . TRP B 1 62 ? 30.135 28.940 21.058 1.00 124.47 ? 277 TRP B CG 1 ATOM 1984 C CD1 . TRP B 1 62 ? 29.144 28.079 21.444 1.00 124.69 ? 277 TRP B CD1 1 ATOM 1985 C CD2 . TRP B 1 62 ? 31.363 28.381 21.547 1.00 125.11 ? 277 TRP B CD2 1 ATOM 1986 N NE1 . TRP B 1 62 ? 29.679 27.020 22.139 1.00 125.01 ? 277 TRP B NE1 1 ATOM 1987 C CE2 . TRP B 1 62 ? 31.038 27.181 22.219 1.00 125.40 ? 277 TRP B CE2 1 ATOM 1988 C CE3 . TRP B 1 62 ? 32.707 28.779 21.485 1.00 125.06 ? 277 TRP B CE3 1 ATOM 1989 C CZ2 . TRP B 1 62 ? 32.009 26.372 22.820 1.00 125.38 ? 277 TRP B CZ2 1 ATOM 1990 C CZ3 . TRP B 1 62 ? 33.673 27.973 22.084 1.00 124.95 ? 277 TRP B CZ3 1 ATOM 1991 C CH2 . TRP B 1 62 ? 33.316 26.785 22.744 1.00 124.94 ? 277 TRP B CH2 1 ATOM 1992 N N . TYR B 1 63 ? 30.969 33.479 20.479 1.00 120.15 ? 278 TYR B N 1 ATOM 1993 C CA . TYR B 1 63 ? 31.226 34.688 19.708 1.00 119.34 ? 278 TYR B CA 1 ATOM 1994 C C . TYR B 1 63 ? 32.633 34.693 19.107 1.00 117.94 ? 278 TYR B C 1 ATOM 1995 O O . TYR B 1 63 ? 33.601 34.295 19.753 1.00 116.72 ? 278 TYR B O 1 ATOM 1996 C CB . TYR B 1 63 ? 31.044 35.927 20.589 1.00 120.94 ? 278 TYR B CB 1 ATOM 1997 C CG . TYR B 1 63 ? 29.828 35.880 21.491 1.00 122.26 ? 278 TYR B CG 1 ATOM 1998 C CD1 . TYR B 1 63 ? 29.844 35.141 22.677 1.00 122.85 ? 278 TYR B CD1 1 ATOM 1999 C CD2 . TYR B 1 63 ? 28.659 36.569 21.159 1.00 122.38 ? 278 TYR B CD2 1 ATOM 2000 C CE1 . TYR B 1 63 ? 28.726 35.088 23.513 1.00 122.91 ? 278 TYR B CE1 1 ATOM 2001 C CE2 . TYR B 1 63 ? 27.532 36.522 21.991 1.00 122.91 ? 278 TYR B CE2 1 ATOM 2002 C CZ . TYR B 1 63 ? 27.575 35.778 23.165 1.00 122.85 ? 278 TYR B CZ 1 ATOM 2003 O OH . TYR B 1 63 ? 26.470 35.713 23.986 1.00 122.55 ? 278 TYR B OH 1 ATOM 2004 N N . VAL B 1 64 ? 32.727 35.163 17.867 1.00 117.07 ? 279 VAL B N 1 ATOM 2005 C CA . VAL B 1 64 ? 33.985 35.239 17.134 1.00 116.54 ? 279 VAL B CA 1 ATOM 2006 C C . VAL B 1 64 ? 34.447 36.690 16.974 1.00 117.08 ? 279 VAL B C 1 ATOM 2007 O O . VAL B 1 64 ? 33.960 37.403 16.095 1.00 117.07 ? 279 VAL B O 1 ATOM 2008 C CB . VAL B 1 64 ? 33.823 34.621 15.731 1.00 115.77 ? 279 VAL B CB 1 ATOM 2009 C CG1 . VAL B 1 64 ? 35.114 34.753 14.945 1.00 115.94 ? 279 VAL B CG1 1 ATOM 2010 C CG2 . VAL B 1 64 ? 33.417 33.170 15.854 1.00 114.95 ? 279 VAL B CG2 1 ATOM 2011 N N . ASP B 1 65 ? 35.398 37.114 17.807 1.00 117.24 ? 280 ASP B N 1 ATOM 2012 C CA . ASP B 1 65 ? 35.915 38.484 17.767 1.00 117.49 ? 280 ASP B CA 1 ATOM 2013 C C . ASP B 1 65 ? 34.760 39.448 17.972 1.00 117.92 ? 280 ASP B C 1 ATOM 2014 O O . ASP B 1 65 ? 34.655 40.468 17.285 1.00 117.83 ? 280 ASP B O 1 ATOM 2015 C CB . ASP B 1 65 ? 36.584 38.783 16.422 1.00 117.68 ? 280 ASP B CB 1 ATOM 2016 C CG . ASP B 1 65 ? 37.923 38.093 16.267 1.00 118.00 ? 280 ASP B CG 1 ATOM 2017 O OD1 . ASP B 1 65 ? 38.825 38.350 17.092 1.00 117.84 ? 280 ASP B OD1 1 ATOM 2018 O OD2 . ASP B 1 65 ? 38.075 37.299 15.316 1.00 117.83 ? 280 ASP B OD2 1 ATOM 2019 N N . GLY B 1 66 ? 33.898 39.116 18.927 1.00 117.98 ? 281 GLY B N 1 ATOM 2020 C CA . GLY B 1 66 ? 32.738 39.941 19.198 1.00 118.06 ? 281 GLY B CA 1 ATOM 2021 C C . GLY B 1 66 ? 31.556 39.387 18.423 1.00 118.26 ? 281 GLY B C 1 ATOM 2022 O O . GLY B 1 66 ? 30.638 38.813 19.010 1.00 118.31 ? 281 GLY B O 1 ATOM 2023 N N . VAL B 1 67 ? 31.591 39.548 17.101 1.00 118.52 ? 282 VAL B N 1 ATOM 2024 C CA . VAL B 1 67 ? 30.530 39.066 16.216 1.00 118.59 ? 282 VAL B CA 1 ATOM 2025 C C . VAL B 1 67 ? 30.160 37.638 16.597 1.00 118.71 ? 282 VAL B C 1 ATOM 2026 O O . VAL B 1 67 ? 30.976 36.919 17.170 1.00 119.18 ? 282 VAL B O 1 ATOM 2027 C CB . VAL B 1 67 ? 30.986 39.083 14.737 1.00 118.60 ? 282 VAL B CB 1 ATOM 2028 C CG1 . VAL B 1 67 ? 29.801 38.807 13.822 1.00 118.44 ? 282 VAL B CG1 1 ATOM 2029 C CG2 . VAL B 1 67 ? 31.631 40.423 14.403 1.00 118.42 ? 282 VAL B CG2 1 ATOM 2030 N N . GLU B 1 68 ? 28.938 37.222 16.280 1.00 118.67 ? 283 GLU B N 1 ATOM 2031 C CA . GLU B 1 68 ? 28.502 35.874 16.625 1.00 118.79 ? 283 GLU B CA 1 ATOM 2032 C C . GLU B 1 68 ? 27.809 35.139 15.478 1.00 118.34 ? 283 GLU B C 1 ATOM 2033 O O . GLU B 1 68 ? 27.591 35.692 14.399 1.00 117.06 ? 283 GLU B O 1 ATOM 2034 C CB . GLU B 1 68 ? 27.556 35.919 17.838 1.00 119.25 ? 283 GLU B CB 1 ATOM 2035 C CG . GLU B 1 68 ? 27.104 34.541 18.328 1.00 120.13 ? 283 GLU B CG 1 ATOM 2036 C CD . GLU B 1 68 ? 25.844 34.581 19.175 1.00 120.20 ? 283 GLU B CD 1 ATOM 2037 O OE1 . GLU B 1 68 ? 24.816 35.101 18.692 1.00 120.21 ? 283 GLU B OE1 1 ATOM 2038 O OE2 . GLU B 1 68 ? 25.878 34.083 20.320 1.00 120.61 ? 283 GLU B OE2 1 ATOM 2039 N N . VAL B 1 69 ? 27.487 33.876 15.743 1.00 118.64 ? 284 VAL B N 1 ATOM 2040 C CA . VAL B 1 69 ? 26.793 32.983 14.825 1.00 118.63 ? 284 VAL B CA 1 ATOM 2041 C C . VAL B 1 69 ? 26.239 31.846 15.682 1.00 118.31 ? 284 VAL B C 1 ATOM 2042 O O . VAL B 1 69 ? 26.880 31.415 16.642 1.00 117.57 ? 284 VAL B O 1 ATOM 2043 C CB . VAL B 1 69 ? 27.740 32.372 13.758 1.00 119.07 ? 284 VAL B CB 1 ATOM 2044 C CG1 . VAL B 1 69 ? 28.259 33.456 12.820 1.00 118.53 ? 284 VAL B CG1 1 ATOM 2045 C CG2 . VAL B 1 69 ? 28.891 31.651 14.440 1.00 119.54 ? 284 VAL B CG2 1 ATOM 2046 N N . HIS B 1 70 ? 25.043 31.378 15.343 1.00 118.75 ? 285 HIS B N 1 ATOM 2047 C CA . HIS B 1 70 ? 24.408 30.289 16.079 1.00 119.05 ? 285 HIS B CA 1 ATOM 2048 C C . HIS B 1 70 ? 24.622 28.960 15.355 1.00 118.33 ? 285 HIS B C 1 ATOM 2049 O O . HIS B 1 70 ? 23.996 28.691 14.328 1.00 118.22 ? 285 HIS B O 1 ATOM 2050 C CB . HIS B 1 70 ? 22.902 30.554 16.242 1.00 120.31 ? 285 HIS B CB 1 ATOM 2051 C CG . HIS B 1 70 ? 22.560 31.488 17.365 1.00 121.10 ? 285 HIS B CG 1 ATOM 2052 N ND1 . HIS B 1 70 ? 22.676 31.133 18.693 1.00 121.40 ? 285 HIS B ND1 1 ATOM 2053 C CD2 . HIS B 1 70 ? 22.088 32.758 17.358 1.00 121.06 ? 285 HIS B CD2 1 ATOM 2054 C CE1 . HIS B 1 70 ? 22.287 32.141 19.453 1.00 120.82 ? 285 HIS B CE1 1 ATOM 2055 N NE2 . HIS B 1 70 ? 21.925 33.139 18.668 1.00 121.09 ? 285 HIS B NE2 1 ATOM 2056 N N . ASN B 1 71 ? 25.518 28.138 15.895 1.00 117.28 ? 286 ASN B N 1 ATOM 2057 C CA . ASN B 1 71 ? 25.823 26.833 15.318 1.00 116.12 ? 286 ASN B CA 1 ATOM 2058 C C . ASN B 1 71 ? 26.922 26.154 16.122 1.00 114.95 ? 286 ASN B C 1 ATOM 2059 O O . ASN B 1 71 ? 28.104 26.299 15.817 1.00 115.44 ? 286 ASN B O 1 ATOM 2060 C CB . ASN B 1 71 ? 26.266 26.975 13.852 1.00 116.40 ? 286 ASN B CB 1 ATOM 2061 C CG . ASN B 1 71 ? 27.484 27.870 13.688 1.00 116.40 ? 286 ASN B CG 1 ATOM 2062 O OD1 . ASN B 1 71 ? 27.421 29.075 13.929 1.00 116.83 ? 286 ASN B OD1 1 ATOM 2063 N ND2 . ASN B 1 71 ? 28.601 27.280 13.277 1.00 116.07 ? 286 ASN B ND2 1 ATOM 2064 N N . ALA B 1 72 ? 26.531 25.410 17.151 1.00 113.35 ? 287 ALA B N 1 ATOM 2065 C CA . ALA B 1 72 ? 27.503 24.724 17.989 1.00 112.01 ? 287 ALA B CA 1 ATOM 2066 C C . ALA B 1 72 ? 26.926 23.477 18.649 1.00 111.12 ? 287 ALA B C 1 ATOM 2067 O O . ALA B 1 72 ? 26.520 23.518 19.809 1.00 111.00 ? 287 ALA B O 1 ATOM 2068 C CB . ALA B 1 72 ? 28.035 25.682 19.054 1.00 111.49 ? 287 ALA B CB 1 ATOM 2069 N N . LYS B 1 73 ? 26.896 22.374 17.906 1.00 110.54 ? 288 LYS B N 1 ATOM 2070 C CA . LYS B 1 73 ? 26.381 21.104 18.419 1.00 110.43 ? 288 LYS B CA 1 ATOM 2071 C C . LYS B 1 73 ? 26.770 20.952 19.887 1.00 110.75 ? 288 LYS B C 1 ATOM 2072 O O . LYS B 1 73 ? 27.824 21.432 20.305 1.00 110.22 ? 288 LYS B O 1 ATOM 2073 C CB . LYS B 1 73 ? 26.959 19.935 17.612 1.00 110.07 ? 288 LYS B CB 1 ATOM 2074 C CG . LYS B 1 73 ? 26.674 19.988 16.111 1.00 109.56 ? 288 LYS B CG 1 ATOM 2075 C CD . LYS B 1 73 ? 27.430 18.894 15.346 1.00 109.31 ? 288 LYS B CD 1 ATOM 2076 C CE . LYS B 1 73 ? 27.054 17.485 15.818 1.00 109.34 ? 288 LYS B CE 1 ATOM 2077 N NZ . LYS B 1 73 ? 27.775 16.397 15.085 1.00 107.03 ? 288 LYS B NZ 1 ATOM 2078 N N . THR B 1 74 ? 25.925 20.290 20.672 1.00 111.66 ? 289 THR B N 1 ATOM 2079 C CA . THR B 1 74 ? 26.224 20.114 22.087 1.00 112.64 ? 289 THR B CA 1 ATOM 2080 C C . THR B 1 74 ? 25.765 18.791 22.682 1.00 113.41 ? 289 THR B C 1 ATOM 2081 O O . THR B 1 74 ? 24.627 18.655 23.123 1.00 112.99 ? 289 THR B O 1 ATOM 2082 C CB . THR B 1 74 ? 25.627 21.255 22.914 1.00 112.03 ? 289 THR B CB 1 ATOM 2083 O OG1 . THR B 1 74 ? 26.172 22.498 22.460 1.00 112.45 ? 289 THR B OG1 1 ATOM 2084 C CG2 . THR B 1 74 ? 25.966 21.079 24.383 1.00 111.91 ? 289 THR B CG2 1 ATOM 2085 N N . LYS B 1 75 ? 26.676 17.825 22.703 1.00 115.35 ? 290 LYS B N 1 ATOM 2086 C CA . LYS B 1 75 ? 26.398 16.504 23.246 1.00 117.80 ? 290 LYS B CA 1 ATOM 2087 C C . LYS B 1 75 ? 25.868 16.591 24.675 1.00 119.35 ? 290 LYS B C 1 ATOM 2088 O O . LYS B 1 75 ? 26.141 17.555 25.390 1.00 118.82 ? 290 LYS B O 1 ATOM 2089 C CB . LYS B 1 75 ? 27.667 15.642 23.190 1.00 118.20 ? 290 LYS B CB 1 ATOM 2090 C CG . LYS B 1 75 ? 27.861 14.931 21.852 1.00 118.11 ? 290 LYS B CG 1 ATOM 2091 C CD . LYS B 1 75 ? 29.302 14.507 21.604 1.00 117.33 ? 290 LYS B CD 1 ATOM 2092 C CE . LYS B 1 75 ? 30.182 15.706 21.278 1.00 116.54 ? 290 LYS B CE 1 ATOM 2093 N NZ . LYS B 1 75 ? 31.510 15.286 20.750 1.00 116.05 ? 290 LYS B NZ 1 ATOM 2094 N N . PRO B 1 76 ? 25.098 15.575 25.103 1.00 121.25 ? 291 PRO B N 1 ATOM 2095 C CA . PRO B 1 76 ? 24.489 15.469 26.436 1.00 122.46 ? 291 PRO B CA 1 ATOM 2096 C C . PRO B 1 76 ? 25.484 15.396 27.595 1.00 123.03 ? 291 PRO B C 1 ATOM 2097 O O . PRO B 1 76 ? 26.692 15.278 27.383 1.00 123.02 ? 291 PRO B O 1 ATOM 2098 C CB . PRO B 1 76 ? 23.645 14.202 26.321 1.00 122.64 ? 291 PRO B CB 1 ATOM 2099 C CG . PRO B 1 76 ? 24.445 13.365 25.370 1.00 122.44 ? 291 PRO B CG 1 ATOM 2100 C CD . PRO B 1 76 ? 24.806 14.370 24.305 1.00 121.75 ? 291 PRO B CD 1 ATOM 2101 N N . ARG B 1 77 ? 24.971 15.465 28.821 1.00 123.64 ? 292 ARG B N 1 ATOM 2102 C CA . ARG B 1 77 ? 25.834 15.407 29.993 1.00 124.77 ? 292 ARG B CA 1 ATOM 2103 C C . ARG B 1 77 ? 26.239 13.991 30.369 1.00 124.83 ? 292 ARG B C 1 ATOM 2104 O O . ARG B 1 77 ? 25.560 13.309 31.137 1.00 124.96 ? 292 ARG B O 1 ATOM 2105 C CB . ARG B 1 77 ? 25.183 16.103 31.194 1.00 125.78 ? 292 ARG B CB 1 ATOM 2106 C CG . ARG B 1 77 ? 23.703 15.828 31.429 1.00 127.06 ? 292 ARG B CG 1 ATOM 2107 C CD . ARG B 1 77 ? 23.297 16.417 32.784 1.00 127.89 ? 292 ARG B CD 1 ATOM 2108 N NE . ARG B 1 77 ? 21.855 16.554 32.965 1.00 128.71 ? 292 ARG B NE 1 ATOM 2109 C CZ . ARG B 1 77 ? 21.104 17.460 32.344 1.00 129.61 ? 292 ARG B CZ 1 ATOM 2110 N NH1 . ARG B 1 77 ? 21.656 18.316 31.493 1.00 129.82 ? 292 ARG B NH1 1 ATOM 2111 N NH2 . ARG B 1 77 ? 19.800 17.516 32.584 1.00 129.65 ? 292 ARG B NH2 1 ATOM 2112 N N . GLU B 1 78 ? 27.365 13.566 29.810 1.00 124.98 ? 293 GLU B N 1 ATOM 2113 C CA . GLU B 1 78 ? 27.924 12.243 30.044 1.00 125.14 ? 293 GLU B CA 1 ATOM 2114 C C . GLU B 1 78 ? 28.162 12.023 31.535 1.00 125.10 ? 293 GLU B C 1 ATOM 2115 O O . GLU B 1 78 ? 29.064 12.619 32.120 1.00 124.72 ? 293 GLU B O 1 ATOM 2116 C CB . GLU B 1 78 ? 29.242 12.124 29.277 1.00 125.63 ? 293 GLU B CB 1 ATOM 2117 C CG . GLU B 1 78 ? 30.008 10.831 29.462 1.00 125.81 ? 293 GLU B CG 1 ATOM 2118 C CD . GLU B 1 78 ? 31.430 10.942 28.933 1.00 126.14 ? 293 GLU B CD 1 ATOM 2119 O OE1 . GLU B 1 78 ? 31.599 11.295 27.745 1.00 125.75 ? 293 GLU B OE1 1 ATOM 2120 O OE2 . GLU B 1 78 ? 32.378 10.686 29.706 1.00 126.00 ? 293 GLU B OE2 1 ATOM 2121 N N . GLU B 1 79 ? 27.341 11.170 32.143 1.00 125.57 ? 294 GLU B N 1 ATOM 2122 C CA . GLU B 1 79 ? 27.459 10.857 33.567 1.00 126.01 ? 294 GLU B CA 1 ATOM 2123 C C . GLU B 1 79 ? 28.935 10.652 33.903 1.00 126.09 ? 294 GLU B C 1 ATOM 2124 O O . GLU B 1 79 ? 29.689 10.136 33.077 1.00 126.48 ? 294 GLU B O 1 ATOM 2125 C CB . GLU B 1 79 ? 26.675 9.579 33.885 1.00 125.97 ? 294 GLU B CB 1 ATOM 2126 C CG . GLU B 1 79 ? 26.556 9.264 35.365 1.00 125.79 ? 294 GLU B CG 1 ATOM 2127 C CD . GLU B 1 79 ? 25.605 10.199 36.082 1.00 125.73 ? 294 GLU B CD 1 ATOM 2128 O OE1 . GLU B 1 79 ? 24.386 10.124 35.816 1.00 125.80 ? 294 GLU B OE1 1 ATOM 2129 O OE2 . GLU B 1 79 ? 26.076 11.011 36.905 1.00 125.82 ? 294 GLU B OE2 1 ATOM 2130 N N . GLN B 1 80 ? 29.354 11.048 35.102 1.00 125.82 ? 295 GLN B N 1 ATOM 2131 C CA . GLN B 1 80 ? 30.758 10.891 35.470 1.00 126.06 ? 295 GLN B CA 1 ATOM 2132 C C . GLN B 1 80 ? 30.990 10.083 36.746 1.00 126.47 ? 295 GLN B C 1 ATOM 2133 O O . GLN B 1 80 ? 30.060 9.815 37.507 1.00 126.20 ? 295 GLN B O 1 ATOM 2134 C CB . GLN B 1 80 ? 31.426 12.264 35.592 1.00 126.14 ? 295 GLN B CB 1 ATOM 2135 C CG . GLN B 1 80 ? 32.940 12.235 35.390 1.00 125.56 ? 295 GLN B CG 1 ATOM 2136 C CD . GLN B 1 80 ? 33.338 11.652 34.042 1.00 125.07 ? 295 GLN B CD 1 ATOM 2137 O OE1 . GLN B 1 80 ? 32.961 12.172 32.990 1.00 123.96 ? 295 GLN B OE1 1 ATOM 2138 N NE2 . GLN B 1 80 ? 34.101 10.562 34.071 1.00 124.46 ? 295 GLN B NE2 1 ATOM 2139 N N . TYR B 1 81 ? 32.248 9.704 36.966 1.00 127.30 ? 296 TYR B N 1 ATOM 2140 C CA . TYR B 1 81 ? 32.652 8.904 38.120 1.00 127.35 ? 296 TYR B CA 1 ATOM 2141 C C . TYR B 1 81 ? 32.954 9.678 39.399 1.00 127.05 ? 296 TYR B C 1 ATOM 2142 O O . TYR B 1 81 ? 33.756 9.234 40.220 1.00 126.72 ? 296 TYR B O 1 ATOM 2143 C CB . TYR B 1 81 ? 33.863 8.034 37.750 1.00 127.88 ? 296 TYR B CB 1 ATOM 2144 C CG . TYR B 1 81 ? 33.512 6.786 36.961 1.00 128.48 ? 296 TYR B CG 1 ATOM 2145 C CD1 . TYR B 1 81 ? 34.509 5.976 36.418 1.00 128.60 ? 296 TYR B CD1 1 ATOM 2146 C CD2 . TYR B 1 81 ? 32.180 6.407 36.773 1.00 128.42 ? 296 TYR B CD2 1 ATOM 2147 C CE1 . TYR B 1 81 ? 34.188 4.819 35.706 1.00 129.15 ? 296 TYR B CE1 1 ATOM 2148 C CE2 . TYR B 1 81 ? 31.849 5.256 36.066 1.00 128.87 ? 296 TYR B CE2 1 ATOM 2149 C CZ . TYR B 1 81 ? 32.855 4.466 35.535 1.00 129.10 ? 296 TYR B CZ 1 ATOM 2150 O OH . TYR B 1 81 ? 32.520 3.329 34.832 1.00 129.04 ? 296 TYR B OH 1 ATOM 2151 N N . ASN B 1 82 ? 32.320 10.833 39.568 1.00 127.10 ? 297 ASN B N 1 ATOM 2152 C CA . ASN B 1 82 ? 32.510 11.631 40.775 1.00 127.23 ? 297 ASN B CA 1 ATOM 2153 C C . ASN B 1 82 ? 31.322 12.556 41.043 1.00 127.48 ? 297 ASN B C 1 ATOM 2154 O O . ASN B 1 82 ? 31.472 13.774 41.144 1.00 127.66 ? 297 ASN B O 1 ATOM 2155 C CB . ASN B 1 82 ? 33.825 12.438 40.716 1.00 126.38 ? 297 ASN B CB 1 ATOM 2156 C CG . ASN B 1 82 ? 33.943 13.309 39.473 1.00 125.75 ? 297 ASN B CG 1 ATOM 2157 O OD1 . ASN B 1 82 ? 32.968 13.919 39.035 1.00 126.03 ? 297 ASN B OD1 1 ATOM 2158 N ND2 . ASN B 1 82 ? 35.153 13.383 38.920 1.00 124.61 ? 297 ASN B ND2 1 ATOM 2159 N N . SER B 1 83 ? 30.139 11.956 41.157 1.00 127.37 ? 298 SER B N 1 ATOM 2160 C CA . SER B 1 83 ? 28.902 12.687 41.428 1.00 127.60 ? 298 SER B CA 1 ATOM 2161 C C . SER B 1 83 ? 28.717 13.933 40.558 1.00 126.93 ? 298 SER B C 1 ATOM 2162 O O . SER B 1 83 ? 28.095 14.911 40.983 1.00 126.89 ? 298 SER B O 1 ATOM 2163 C CB . SER B 1 83 ? 28.840 13.091 42.910 1.00 128.38 ? 298 SER B CB 1 ATOM 2164 O OG . SER B 1 83 ? 28.761 11.962 43.766 1.00 128.79 ? 298 SER B OG 1 ATOM 2165 N N . THR B 1 84 ? 29.252 13.902 39.342 1.00 125.68 ? 299 THR B N 1 ATOM 2166 C CA . THR B 1 84 ? 29.124 15.045 38.447 1.00 124.46 ? 299 THR B CA 1 ATOM 2167 C C . THR B 1 84 ? 29.000 14.602 36.996 1.00 123.66 ? 299 THR B C 1 ATOM 2168 O O . THR B 1 84 ? 28.852 13.414 36.707 1.00 123.87 ? 299 THR B O 1 ATOM 2169 C CB . THR B 1 84 ? 30.340 15.991 38.566 1.00 124.50 ? 299 THR B CB 1 ATOM 2170 O OG1 . THR B 1 84 ? 31.496 15.363 38.002 1.00 124.37 ? 299 THR B OG1 1 ATOM 2171 C CG2 . THR B 1 84 ? 30.620 16.321 40.023 1.00 123.99 ? 299 THR B CG2 1 ATOM 2172 N N . TYR B 1 85 ? 29.053 15.566 36.084 1.00 122.57 ? 300 TYR B N 1 ATOM 2173 C CA . TYR B 1 85 ? 28.960 15.274 34.662 1.00 121.75 ? 300 TYR B CA 1 ATOM 2174 C C . TYR B 1 85 ? 30.079 15.981 33.905 1.00 121.06 ? 300 TYR B C 1 ATOM 2175 O O . TYR B 1 85 ? 30.893 16.698 34.492 1.00 120.84 ? 300 TYR B O 1 ATOM 2176 C CB . TYR B 1 85 ? 27.623 15.749 34.089 1.00 122.56 ? 300 TYR B CB 1 ATOM 2177 C CG . TYR B 1 85 ? 26.389 15.200 34.762 1.00 123.28 ? 300 TYR B CG 1 ATOM 2178 C CD1 . TYR B 1 85 ? 26.024 15.617 36.040 1.00 123.89 ? 300 TYR B CD1 1 ATOM 2179 C CD2 . TYR B 1 85 ? 25.563 14.287 34.106 1.00 123.73 ? 300 TYR B CD2 1 ATOM 2180 C CE1 . TYR B 1 85 ? 24.863 15.143 36.649 1.00 124.57 ? 300 TYR B CE1 1 ATOM 2181 C CE2 . TYR B 1 85 ? 24.401 13.806 34.704 1.00 124.14 ? 300 TYR B CE2 1 ATOM 2182 C CZ . TYR B 1 85 ? 24.057 14.239 35.976 1.00 124.65 ? 300 TYR B CZ 1 ATOM 2183 O OH . TYR B 1 85 ? 22.909 13.772 36.575 1.00 125.59 ? 300 TYR B OH 1 ATOM 2184 N N . ARG B 1 86 ? 30.099 15.772 32.593 1.00 119.94 ? 301 ARG B N 1 ATOM 2185 C CA . ARG B 1 86 ? 31.080 16.388 31.711 1.00 118.10 ? 301 ARG B CA 1 ATOM 2186 C C . ARG B 1 86 ? 30.306 16.991 30.543 1.00 115.88 ? 301 ARG B C 1 ATOM 2187 O O . ARG B 1 86 ? 29.983 16.302 29.573 1.00 115.35 ? 301 ARG B O 1 ATOM 2188 C CB . ARG B 1 86 ? 32.077 15.339 31.202 1.00 119.74 ? 301 ARG B CB 1 ATOM 2189 C CG . ARG B 1 86 ? 33.239 15.903 30.382 1.00 121.15 ? 301 ARG B CG 1 ATOM 2190 C CD . ARG B 1 86 ? 34.270 14.819 30.077 1.00 122.53 ? 301 ARG B CD 1 ATOM 2191 N NE . ARG B 1 86 ? 35.503 15.353 29.498 1.00 124.11 ? 301 ARG B NE 1 ATOM 2192 C CZ . ARG B 1 86 ? 35.646 15.720 28.227 1.00 124.90 ? 301 ARG B CZ 1 ATOM 2193 N NH1 . ARG B 1 86 ? 34.628 15.612 27.383 1.00 124.91 ? 301 ARG B NH1 1 ATOM 2194 N NH2 . ARG B 1 86 ? 36.811 16.198 27.801 1.00 124.39 ? 301 ARG B NH2 1 ATOM 2195 N N . VAL B 1 87 ? 29.988 18.276 30.655 1.00 113.23 ? 302 VAL B N 1 ATOM 2196 C CA . VAL B 1 87 ? 29.251 18.966 29.605 1.00 110.70 ? 302 VAL B CA 1 ATOM 2197 C C . VAL B 1 87 ? 30.234 19.518 28.573 1.00 108.86 ? 302 VAL B C 1 ATOM 2198 O O . VAL B 1 87 ? 31.116 20.316 28.905 1.00 108.95 ? 302 VAL B O 1 ATOM 2199 C CB . VAL B 1 87 ? 28.411 20.127 30.184 1.00 110.48 ? 302 VAL B CB 1 ATOM 2200 C CG1 . VAL B 1 87 ? 27.538 20.733 29.099 1.00 109.56 ? 302 VAL B CG1 1 ATOM 2201 C CG2 . VAL B 1 87 ? 27.557 19.624 31.332 1.00 109.43 ? 302 VAL B CG2 1 ATOM 2202 N N . VAL B 1 88 ? 30.079 19.080 27.325 1.00 105.73 ? 303 VAL B N 1 ATOM 2203 C CA . VAL B 1 88 ? 30.946 19.510 26.231 1.00 101.71 ? 303 VAL B CA 1 ATOM 2204 C C . VAL B 1 88 ? 30.155 20.193 25.119 1.00 98.56 ? 303 VAL B C 1 ATOM 2205 O O . VAL B 1 88 ? 29.093 19.721 24.721 1.00 97.54 ? 303 VAL B O 1 ATOM 2206 C CB . VAL B 1 88 ? 31.715 18.309 25.625 1.00 102.20 ? 303 VAL B CB 1 ATOM 2207 C CG1 . VAL B 1 88 ? 32.490 18.746 24.391 1.00 102.20 ? 303 VAL B CG1 1 ATOM 2208 C CG2 . VAL B 1 88 ? 32.665 17.728 26.661 1.00 102.19 ? 303 VAL B CG2 1 ATOM 2209 N N . SER B 1 89 ? 30.687 21.308 24.630 1.00 95.29 ? 304 SER B N 1 ATOM 2210 C CA . SER B 1 89 ? 30.058 22.072 23.560 1.00 92.82 ? 304 SER B CA 1 ATOM 2211 C C . SER B 1 89 ? 31.089 22.318 22.463 1.00 91.51 ? 304 SER B C 1 ATOM 2212 O O . SER B 1 89 ? 32.105 22.975 22.705 1.00 92.48 ? 304 SER B O 1 ATOM 2213 C CB . SER B 1 89 ? 29.554 23.415 24.096 1.00 92.20 ? 304 SER B CB 1 ATOM 2214 O OG . SER B 1 89 ? 28.887 24.158 23.086 1.00 90.60 ? 304 SER B OG 1 ATOM 2215 N N . VAL B 1 90 ? 30.831 21.799 21.262 1.00 88.12 ? 305 VAL B N 1 ATOM 2216 C CA . VAL B 1 90 ? 31.757 21.972 20.145 1.00 84.39 ? 305 VAL B CA 1 ATOM 2217 C C . VAL B 1 90 ? 31.237 22.912 19.065 1.00 82.15 ? 305 VAL B C 1 ATOM 2218 O O . VAL B 1 90 ? 30.063 22.893 18.725 1.00 82.04 ? 305 VAL B O 1 ATOM 2219 C CB . VAL B 1 90 ? 32.107 20.620 19.491 1.00 83.96 ? 305 VAL B CB 1 ATOM 2220 C CG1 . VAL B 1 90 ? 32.823 19.727 20.495 1.00 83.51 ? 305 VAL B CG1 1 ATOM 2221 C CG2 . VAL B 1 90 ? 30.848 19.949 18.977 1.00 83.44 ? 305 VAL B CG2 1 ATOM 2222 N N . LEU B 1 91 ? 32.135 23.729 18.526 1.00 80.15 ? 306 LEU B N 1 ATOM 2223 C CA . LEU B 1 91 ? 31.797 24.691 17.485 1.00 77.49 ? 306 LEU B CA 1 ATOM 2224 C C . LEU B 1 91 ? 32.749 24.515 16.298 1.00 76.52 ? 306 LEU B C 1 ATOM 2225 O O . LEU B 1 91 ? 33.966 24.552 16.465 1.00 76.35 ? 306 LEU B O 1 ATOM 2226 C CB . LEU B 1 91 ? 31.928 26.108 18.053 1.00 76.75 ? 306 LEU B CB 1 ATOM 2227 C CG . LEU B 1 91 ? 31.375 27.328 17.305 1.00 76.10 ? 306 LEU B CG 1 ATOM 2228 C CD1 . LEU B 1 91 ? 31.676 28.558 18.133 1.00 74.18 ? 306 LEU B CD1 1 ATOM 2229 C CD2 . LEU B 1 91 ? 31.989 27.471 15.918 1.00 75.67 ? 306 LEU B CD2 1 ATOM 2230 N N . THR B 1 92 ? 32.195 24.316 15.105 1.00 75.02 ? 307 THR B N 1 ATOM 2231 C CA . THR B 1 92 ? 33.009 24.154 13.907 1.00 73.79 ? 307 THR B CA 1 ATOM 2232 C C . THR B 1 92 ? 33.446 25.511 13.388 1.00 73.62 ? 307 THR B C 1 ATOM 2233 O O . THR B 1 92 ? 32.628 26.413 13.226 1.00 74.14 ? 307 THR B O 1 ATOM 2234 C CB . THR B 1 92 ? 32.238 23.431 12.799 1.00 74.02 ? 307 THR B CB 1 ATOM 2235 O OG1 . THR B 1 92 ? 32.335 22.019 13.007 1.00 75.72 ? 307 THR B OG1 1 ATOM 2236 C CG2 . THR B 1 92 ? 32.804 23.777 11.432 1.00 73.76 ? 307 THR B CG2 1 ATOM 2237 N N . VAL B 1 93 ? 34.738 25.645 13.106 1.00 72.92 ? 308 VAL B N 1 ATOM 2238 C CA . VAL B 1 93 ? 35.285 26.909 12.633 1.00 71.82 ? 308 VAL B CA 1 ATOM 2239 C C . VAL B 1 93 ? 35.838 26.842 11.227 1.00 71.54 ? 308 VAL B C 1 ATOM 2240 O O . VAL B 1 93 ? 35.986 25.766 10.653 1.00 71.31 ? 308 VAL B O 1 ATOM 2241 C CB . VAL B 1 93 ? 36.409 27.383 13.548 1.00 71.27 ? 308 VAL B CB 1 ATOM 2242 C CG1 . VAL B 1 93 ? 35.894 27.525 14.962 1.00 73.23 ? 308 VAL B CG1 1 ATOM 2243 C CG2 . VAL B 1 93 ? 37.551 26.396 13.504 1.00 71.06 ? 308 VAL B CG2 1 ATOM 2244 N N . LEU B 1 94 ? 36.154 28.009 10.678 1.00 71.79 ? 309 LEU B N 1 ATOM 2245 C CA . LEU B 1 94 ? 36.708 28.084 9.339 1.00 72.89 ? 309 LEU B CA 1 ATOM 2246 C C . LEU B 1 94 ? 38.228 28.128 9.422 1.00 72.91 ? 309 LEU B C 1 ATOM 2247 O O . LEU B 1 94 ? 38.785 28.913 10.184 1.00 73.39 ? 309 LEU B O 1 ATOM 2248 C CB . LEU B 1 94 ? 36.177 29.326 8.610 1.00 74.11 ? 309 LEU B CB 1 ATOM 2249 C CG . LEU B 1 94 ? 34.697 29.333 8.190 1.00 74.36 ? 309 LEU B CG 1 ATOM 2250 C CD1 . LEU B 1 94 ? 33.794 29.448 9.411 1.00 73.94 ? 309 LEU B CD1 1 ATOM 2251 C CD2 . LEU B 1 94 ? 34.446 30.492 7.246 1.00 74.33 ? 309 LEU B CD2 1 ATOM 2252 N N . HIS B 1 95 ? 38.886 27.277 8.640 1.00 72.36 ? 310 HIS B N 1 ATOM 2253 C CA . HIS B 1 95 ? 40.344 27.197 8.612 1.00 72.27 ? 310 HIS B CA 1 ATOM 2254 C C . HIS B 1 95 ? 41.093 28.516 8.747 1.00 73.51 ? 310 HIS B C 1 ATOM 2255 O O . HIS B 1 95 ? 41.642 28.824 9.807 1.00 73.85 ? 310 HIS B O 1 ATOM 2256 C CB . HIS B 1 95 ? 40.800 26.532 7.326 1.00 70.85 ? 310 HIS B CB 1 ATOM 2257 C CG . HIS B 1 95 ? 40.538 25.067 7.285 1.00 70.70 ? 310 HIS B CG 1 ATOM 2258 N ND1 . HIS B 1 95 ? 39.293 24.531 7.521 1.00 71.08 ? 310 HIS B ND1 1 ATOM 2259 C CD2 . HIS B 1 95 ? 41.359 24.023 7.028 1.00 71.34 ? 310 HIS B CD2 1 ATOM 2260 C CE1 . HIS B 1 95 ? 39.357 23.216 7.410 1.00 72.22 ? 310 HIS B CE1 1 ATOM 2261 N NE2 . HIS B 1 95 ? 40.600 22.882 7.111 1.00 71.95 ? 310 HIS B NE2 1 ATOM 2262 N N . GLN B 1 96 ? 41.131 29.278 7.656 1.00 74.61 ? 311 GLN B N 1 ATOM 2263 C CA . GLN B 1 96 ? 41.830 30.560 7.618 1.00 75.48 ? 311 GLN B CA 1 ATOM 2264 C C . GLN B 1 96 ? 41.400 31.504 8.734 1.00 74.85 ? 311 GLN B C 1 ATOM 2265 O O . GLN B 1 96 ? 42.111 32.451 9.061 1.00 74.38 ? 311 GLN B O 1 ATOM 2266 C CB . GLN B 1 96 ? 41.636 31.231 6.255 1.00 77.08 ? 311 GLN B CB 1 ATOM 2267 C CG . GLN B 1 96 ? 40.189 31.573 5.927 1.00 82.08 ? 311 GLN B CG 1 ATOM 2268 C CD . GLN B 1 96 ? 39.273 30.361 6.000 1.00 84.64 ? 311 GLN B CD 1 ATOM 2269 O OE1 . GLN B 1 96 ? 39.537 29.333 5.369 1.00 85.64 ? 311 GLN B OE1 1 ATOM 2270 N NE2 . GLN B 1 96 ? 38.190 30.474 6.773 1.00 84.44 ? 311 GLN B NE2 1 ATOM 2271 N N . ASP B 1 97 ? 40.235 31.260 9.320 1.00 74.53 ? 312 ASP B N 1 ATOM 2272 C CA . ASP B 1 97 ? 39.804 32.114 10.412 1.00 75.48 ? 312 ASP B CA 1 ATOM 2273 C C . ASP B 1 97 ? 40.635 31.742 11.630 1.00 74.25 ? 312 ASP B C 1 ATOM 2274 O O . ASP B 1 97 ? 41.092 32.605 12.370 1.00 75.45 ? 312 ASP B O 1 ATOM 2275 C CB . ASP B 1 97 ? 38.308 31.942 10.693 1.00 77.88 ? 312 ASP B CB 1 ATOM 2276 C CG . ASP B 1 97 ? 37.509 33.190 10.334 1.00 79.90 ? 312 ASP B CG 1 ATOM 2277 O OD1 . ASP B 1 97 ? 37.586 33.640 9.166 1.00 80.01 ? 312 ASP B OD1 1 ATOM 2278 O OD2 . ASP B 1 97 ? 36.812 33.729 11.220 1.00 81.01 ? 312 ASP B OD2 1 ATOM 2279 N N . TRP B 1 98 ? 40.846 30.450 11.836 1.00 72.58 ? 313 TRP B N 1 ATOM 2280 C CA . TRP B 1 98 ? 41.664 30.033 12.956 1.00 70.52 ? 313 TRP B CA 1 ATOM 2281 C C . TRP B 1 98 ? 43.088 30.461 12.647 1.00 69.90 ? 313 TRP B C 1 ATOM 2282 O O . TRP B 1 98 ? 43.727 31.166 13.438 1.00 69.68 ? 313 TRP B O 1 ATOM 2283 C CB . TRP B 1 98 ? 41.627 28.521 13.142 1.00 69.85 ? 313 TRP B CB 1 ATOM 2284 C CG . TRP B 1 98 ? 42.644 28.100 14.122 1.00 69.11 ? 313 TRP B CG 1 ATOM 2285 C CD1 . TRP B 1 98 ? 43.895 27.624 13.854 1.00 69.30 ? 313 TRP B CD1 1 ATOM 2286 C CD2 . TRP B 1 98 ? 42.563 28.251 15.538 1.00 69.04 ? 313 TRP B CD2 1 ATOM 2287 N NE1 . TRP B 1 98 ? 44.604 27.477 15.021 1.00 70.20 ? 313 TRP B NE1 1 ATOM 2288 C CE2 . TRP B 1 98 ? 43.809 27.854 16.072 1.00 69.76 ? 313 TRP B CE2 1 ATOM 2289 C CE3 . TRP B 1 98 ? 41.560 28.690 16.412 1.00 68.67 ? 313 TRP B CE3 1 ATOM 2290 C CZ2 . TRP B 1 98 ? 44.080 27.880 17.445 1.00 69.17 ? 313 TRP B CZ2 1 ATOM 2291 C CZ3 . TRP B 1 98 ? 41.829 28.717 17.779 1.00 69.38 ? 313 TRP B CZ3 1 ATOM 2292 C CH2 . TRP B 1 98 ? 43.080 28.313 18.280 1.00 69.30 ? 313 TRP B CH2 1 ATOM 2293 N N . LEU B 1 99 ? 43.573 30.026 11.484 1.00 67.89 ? 314 LEU B N 1 ATOM 2294 C CA . LEU B 1 99 ? 44.916 30.350 11.027 1.00 65.71 ? 314 LEU B CA 1 ATOM 2295 C C . LEU B 1 99 ? 45.166 31.858 11.012 1.00 65.46 ? 314 LEU B C 1 ATOM 2296 O O . LEU B 1 99 ? 46.305 32.308 11.124 1.00 64.91 ? 314 LEU B O 1 ATOM 2297 C CB . LEU B 1 99 ? 45.150 29.754 9.640 1.00 63.83 ? 314 LEU B CB 1 ATOM 2298 C CG . LEU B 1 99 ? 45.200 28.226 9.598 1.00 63.19 ? 314 LEU B CG 1 ATOM 2299 C CD1 . LEU B 1 99 ? 45.576 27.739 8.205 1.00 62.17 ? 314 LEU B CD1 1 ATOM 2300 C CD2 . LEU B 1 99 ? 46.226 27.738 10.606 1.00 64.24 ? 314 LEU B CD2 1 ATOM 2301 N N . ASN B 1 100 ? 44.103 32.637 10.871 1.00 65.87 ? 315 ASN B N 1 ATOM 2302 C CA . ASN B 1 100 ? 44.234 34.081 10.881 1.00 67.47 ? 315 ASN B CA 1 ATOM 2303 C C . ASN B 1 100 ? 43.764 34.592 12.233 1.00 69.66 ? 315 ASN B C 1 ATOM 2304 O O . ASN B 1 100 ? 42.715 35.210 12.342 1.00 70.89 ? 315 ASN B O 1 ATOM 2305 C CB . ASN B 1 100 ? 43.409 34.706 9.756 1.00 66.94 ? 315 ASN B CB 1 ATOM 2306 C CG . ASN B 1 100 ? 44.064 34.546 8.387 1.00 66.41 ? 315 ASN B CG 1 ATOM 2307 O OD1 . ASN B 1 100 ? 43.534 35.007 7.377 1.00 65.52 ? 315 ASN B OD1 1 ATOM 2308 N ND2 . ASN B 1 100 ? 45.221 33.895 8.353 1.00 65.59 ? 315 ASN B ND2 1 ATOM 2309 N N . GLY B 1 101 ? 44.558 34.303 13.259 1.00 72.89 ? 316 GLY B N 1 ATOM 2310 C CA . GLY B 1 101 ? 44.274 34.711 14.626 1.00 75.84 ? 316 GLY B CA 1 ATOM 2311 C C . GLY B 1 101 ? 42.903 35.251 14.987 1.00 79.33 ? 316 GLY B C 1 ATOM 2312 O O . GLY B 1 101 ? 42.765 36.434 15.299 1.00 80.06 ? 316 GLY B O 1 ATOM 2313 N N . LYS B 1 102 ? 41.889 34.394 14.955 1.00 82.36 ? 317 LYS B N 1 ATOM 2314 C CA . LYS B 1 102 ? 40.530 34.803 15.312 1.00 85.79 ? 317 LYS B CA 1 ATOM 2315 C C . LYS B 1 102 ? 40.305 34.336 16.745 1.00 88.67 ? 317 LYS B C 1 ATOM 2316 O O . LYS B 1 102 ? 40.859 33.312 17.153 1.00 90.09 ? 317 LYS B O 1 ATOM 2317 C CB . LYS B 1 102 ? 39.505 34.134 14.388 1.00 85.51 ? 317 LYS B CB 1 ATOM 2318 C CG . LYS B 1 102 ? 38.597 35.095 13.621 1.00 85.55 ? 317 LYS B CG 1 ATOM 2319 C CD . LYS B 1 102 ? 39.400 36.036 12.727 1.00 85.05 ? 317 LYS B CD 1 ATOM 2320 C CE . LYS B 1 102 ? 38.505 36.935 11.880 1.00 84.67 ? 317 LYS B CE 1 ATOM 2321 N NZ . LYS B 1 102 ? 37.770 36.187 10.824 1.00 83.97 ? 317 LYS B NZ 1 ATOM 2322 N N . GLU B 1 103 ? 39.507 35.075 17.512 1.00 91.36 ? 318 GLU B N 1 ATOM 2323 C CA . GLU B 1 103 ? 39.236 34.694 18.898 1.00 94.44 ? 318 GLU B CA 1 ATOM 2324 C C . GLU B 1 103 ? 37.872 34.030 19.045 1.00 95.75 ? 318 GLU B C 1 ATOM 2325 O O . GLU B 1 103 ? 36.962 34.292 18.261 1.00 96.20 ? 318 GLU B O 1 ATOM 2326 C CB . GLU B 1 103 ? 39.312 35.915 19.812 1.00 96.04 ? 318 GLU B CB 1 ATOM 2327 C CG . GLU B 1 103 ? 40.678 36.574 19.838 1.00 98.40 ? 318 GLU B CG 1 ATOM 2328 C CD . GLU B 1 103 ? 40.809 37.592 20.955 1.00 100.08 ? 318 GLU B CD 1 ATOM 2329 O OE1 . GLU B 1 103 ? 41.887 38.219 21.062 1.00 100.59 ? 318 GLU B OE1 1 ATOM 2330 O OE2 . GLU B 1 103 ? 39.836 37.761 21.727 1.00 101.21 ? 318 GLU B OE2 1 ATOM 2331 N N . TYR B 1 104 ? 37.735 33.163 20.045 1.00 97.00 ? 319 TYR B N 1 ATOM 2332 C CA . TYR B 1 104 ? 36.477 32.459 20.267 1.00 98.63 ? 319 TYR B CA 1 ATOM 2333 C C . TYR B 1 104 ? 36.091 32.452 21.745 1.00 102.05 ? 319 TYR B C 1 ATOM 2334 O O . TYR B 1 104 ? 36.892 32.079 22.605 1.00 102.62 ? 319 TYR B O 1 ATOM 2335 C CB . TYR B 1 104 ? 36.583 31.025 19.727 1.00 95.19 ? 319 TYR B CB 1 ATOM 2336 C CG . TYR B 1 104 ? 36.906 30.967 18.246 1.00 92.16 ? 319 TYR B CG 1 ATOM 2337 C CD1 . TYR B 1 104 ? 38.163 31.326 17.771 1.00 91.02 ? 319 TYR B CD1 1 ATOM 2338 C CD2 . TYR B 1 104 ? 35.932 30.622 17.314 1.00 91.60 ? 319 TYR B CD2 1 ATOM 2339 C CE1 . TYR B 1 104 ? 38.442 31.354 16.405 1.00 89.82 ? 319 TYR B CE1 1 ATOM 2340 C CE2 . TYR B 1 104 ? 36.200 30.648 15.944 1.00 89.95 ? 319 TYR B CE2 1 ATOM 2341 C CZ . TYR B 1 104 ? 37.455 31.018 15.497 1.00 89.32 ? 319 TYR B CZ 1 ATOM 2342 O OH . TYR B 1 104 ? 37.718 31.071 14.144 1.00 88.22 ? 319 TYR B OH 1 ATOM 2343 N N . LYS B 1 105 ? 34.856 32.867 22.029 1.00 105.56 ? 320 LYS B N 1 ATOM 2344 C CA . LYS B 1 105 ? 34.349 32.941 23.399 1.00 109.12 ? 320 LYS B CA 1 ATOM 2345 C C . LYS B 1 105 ? 33.245 31.932 23.719 1.00 110.92 ? 320 LYS B C 1 ATOM 2346 O O . LYS B 1 105 ? 32.315 31.745 22.935 1.00 110.79 ? 320 LYS B O 1 ATOM 2347 C CB . LYS B 1 105 ? 33.812 34.348 23.681 1.00 110.45 ? 320 LYS B CB 1 ATOM 2348 C CG . LYS B 1 105 ? 34.844 35.467 23.581 1.00 111.96 ? 320 LYS B CG 1 ATOM 2349 C CD . LYS B 1 105 ? 34.194 36.849 23.708 1.00 112.48 ? 320 LYS B CD 1 ATOM 2350 C CE . LYS B 1 105 ? 33.460 37.015 25.035 1.00 112.98 ? 320 LYS B CE 1 ATOM 2351 N NZ . LYS B 1 105 ? 32.862 38.373 25.182 1.00 113.17 ? 320 LYS B NZ 1 ATOM 2352 N N . CYS B 1 106 ? 33.352 31.298 24.884 1.00 113.54 ? 321 CYS B N 1 ATOM 2353 C CA . CYS B 1 106 ? 32.359 30.327 25.343 1.00 116.06 ? 321 CYS B CA 1 ATOM 2354 C C . CYS B 1 106 ? 31.861 30.749 26.733 1.00 118.71 ? 321 CYS B C 1 ATOM 2355 O O . CYS B 1 106 ? 32.633 30.768 27.697 1.00 119.43 ? 321 CYS B O 1 ATOM 2356 C CB . CYS B 1 106 ? 32.964 28.908 25.406 1.00 114.79 ? 321 CYS B CB 1 ATOM 2357 S SG . CYS B 1 106 ? 31.819 27.636 26.053 1.00 113.17 ? 321 CYS B SG 1 ATOM 2358 N N . LYS B 1 107 ? 30.577 31.101 26.827 1.00 121.12 ? 322 LYS B N 1 ATOM 2359 C CA . LYS B 1 107 ? 29.984 31.518 28.098 1.00 123.16 ? 322 LYS B CA 1 ATOM 2360 C C . LYS B 1 107 ? 29.110 30.413 28.680 1.00 124.72 ? 322 LYS B C 1 ATOM 2361 O O . LYS B 1 107 ? 28.024 30.125 28.172 1.00 124.14 ? 322 LYS B O 1 ATOM 2362 C CB . LYS B 1 107 ? 29.149 32.791 27.915 1.00 123.48 ? 322 LYS B CB 1 ATOM 2363 C CG . LYS B 1 107 ? 28.622 33.383 29.223 1.00 124.00 ? 322 LYS B CG 1 ATOM 2364 C CD . LYS B 1 107 ? 27.880 34.701 28.995 1.00 123.62 ? 322 LYS B CD 1 ATOM 2365 C CE . LYS B 1 107 ? 27.360 35.300 30.303 1.00 122.76 ? 322 LYS B CE 1 ATOM 2366 N NZ . LYS B 1 107 ? 28.449 35.673 31.250 1.00 121.91 ? 322 LYS B NZ 1 ATOM 2367 N N . VAL B 1 108 ? 29.602 29.803 29.753 1.00 127.18 ? 323 VAL B N 1 ATOM 2368 C CA . VAL B 1 108 ? 28.903 28.717 30.436 1.00 129.89 ? 323 VAL B CA 1 ATOM 2369 C C . VAL B 1 108 ? 28.020 29.292 31.547 1.00 131.63 ? 323 VAL B C 1 ATOM 2370 O O . VAL B 1 108 ? 28.536 29.844 32.520 1.00 132.12 ? 323 VAL B O 1 ATOM 2371 C CB . VAL B 1 108 ? 29.917 27.731 31.074 1.00 130.00 ? 323 VAL B CB 1 ATOM 2372 C CG1 . VAL B 1 108 ? 29.221 26.430 31.446 1.00 130.16 ? 323 VAL B CG1 1 ATOM 2373 C CG2 . VAL B 1 108 ? 31.079 27.479 30.118 1.00 130.06 ? 323 VAL B CG2 1 ATOM 2374 N N . SER B 1 109 ? 26.699 29.154 31.406 1.00 133.16 ? 324 SER B N 1 ATOM 2375 C CA . SER B 1 109 ? 25.744 29.671 32.398 1.00 134.00 ? 324 SER B CA 1 ATOM 2376 C C . SER B 1 109 ? 25.203 28.582 33.343 1.00 134.39 ? 324 SER B C 1 ATOM 2377 O O . SER B 1 109 ? 24.481 27.680 32.914 1.00 134.35 ? 324 SER B O 1 ATOM 2378 C CB . SER B 1 109 ? 24.571 30.361 31.684 1.00 133.83 ? 324 SER B CB 1 ATOM 2379 O OG . SER B 1 109 ? 25.021 31.380 30.802 1.00 133.01 ? 324 SER B OG 1 ATOM 2380 N N . ASN B 1 110 ? 25.538 28.679 34.629 1.00 135.02 ? 325 ASN B N 1 ATOM 2381 C CA . ASN B 1 110 ? 25.093 27.688 35.608 1.00 135.57 ? 325 ASN B CA 1 ATOM 2382 C C . ASN B 1 110 ? 24.513 28.310 36.884 1.00 135.79 ? 325 ASN B C 1 ATOM 2383 O O . ASN B 1 110 ? 24.304 29.524 36.962 1.00 135.54 ? 325 ASN B O 1 ATOM 2384 C CB . ASN B 1 110 ? 26.263 26.767 35.977 1.00 135.30 ? 325 ASN B CB 1 ATOM 2385 C CG . ASN B 1 110 ? 25.811 25.468 36.622 1.00 135.10 ? 325 ASN B CG 1 ATOM 2386 O OD1 . ASN B 1 110 ? 26.626 24.712 37.151 1.00 135.01 ? 325 ASN B OD1 1 ATOM 2387 N ND2 . ASN B 1 110 ? 24.511 25.197 36.569 1.00 134.87 ? 325 ASN B ND2 1 ATOM 2388 N N . LYS B 1 111 ? 24.264 27.458 37.878 1.00 135.96 ? 326 LYS B N 1 ATOM 2389 C CA . LYS B 1 111 ? 23.700 27.865 39.167 1.00 135.89 ? 326 LYS B CA 1 ATOM 2390 C C . LYS B 1 111 ? 24.778 28.361 40.133 1.00 135.95 ? 326 LYS B C 1 ATOM 2391 O O . LYS B 1 111 ? 24.820 29.547 40.467 1.00 136.12 ? 326 LYS B O 1 ATOM 2392 C CB . LYS B 1 111 ? 22.933 26.684 39.790 1.00 135.64 ? 326 LYS B CB 1 ATOM 2393 C CG . LYS B 1 111 ? 22.199 26.982 41.102 1.00 135.10 ? 326 LYS B CG 1 ATOM 2394 C CD . LYS B 1 111 ? 23.150 27.098 42.288 1.00 134.57 ? 326 LYS B CD 1 ATOM 2395 C CE . LYS B 1 111 ? 22.399 27.357 43.581 1.00 133.68 ? 326 LYS B CE 1 ATOM 2396 N NZ . LYS B 1 111 ? 21.482 26.235 43.911 1.00 133.27 ? 326 LYS B NZ 1 ATOM 2397 N N . ALA B 1 112 ? 25.641 27.452 40.584 1.00 135.71 ? 327 ALA B N 1 ATOM 2398 C CA . ALA B 1 112 ? 26.717 27.800 41.512 1.00 135.22 ? 327 ALA B CA 1 ATOM 2399 C C . ALA B 1 112 ? 27.741 28.702 40.829 1.00 134.96 ? 327 ALA B C 1 ATOM 2400 O O . ALA B 1 112 ? 28.916 28.729 41.203 1.00 134.65 ? 327 ALA B O 1 ATOM 2401 C CB . ALA B 1 112 ? 27.395 26.533 42.030 1.00 135.10 ? 327 ALA B CB 1 ATOM 2402 N N . LEU B 1 113 ? 27.276 29.434 39.821 1.00 134.66 ? 328 LEU B N 1 ATOM 2403 C CA . LEU B 1 113 ? 28.113 30.351 39.059 1.00 134.19 ? 328 LEU B CA 1 ATOM 2404 C C . LEU B 1 113 ? 27.375 31.682 38.898 1.00 133.54 ? 328 LEU B C 1 ATOM 2405 O O . LEU B 1 113 ? 26.581 31.857 37.968 1.00 133.51 ? 328 LEU B O 1 ATOM 2406 C CB . LEU B 1 113 ? 28.431 29.750 37.681 1.00 133.98 ? 328 LEU B CB 1 ATOM 2407 C CG . LEU B 1 113 ? 29.058 28.348 37.673 1.00 133.80 ? 328 LEU B CG 1 ATOM 2408 C CD1 . LEU B 1 113 ? 29.219 27.869 36.245 1.00 133.49 ? 328 LEU B CD1 1 ATOM 2409 C CD2 . LEU B 1 113 ? 30.408 28.373 38.379 1.00 133.68 ? 328 LEU B CD2 1 ATOM 2410 N N . PRO B 1 114 ? 27.623 32.636 39.815 1.00 132.64 ? 329 PRO B N 1 ATOM 2411 C CA . PRO B 1 114 ? 26.984 33.957 39.779 1.00 131.75 ? 329 PRO B CA 1 ATOM 2412 C C . PRO B 1 114 ? 27.318 34.682 38.480 1.00 130.93 ? 329 PRO B C 1 ATOM 2413 O O . PRO B 1 114 ? 26.429 35.172 37.775 1.00 130.60 ? 329 PRO B O 1 ATOM 2414 C CB . PRO B 1 114 ? 27.570 34.654 41.006 1.00 131.76 ? 329 PRO B CB 1 ATOM 2415 C CG . PRO B 1 114 ? 28.936 34.045 41.111 1.00 131.79 ? 329 PRO B CG 1 ATOM 2416 C CD . PRO B 1 114 ? 28.649 32.582 40.873 1.00 132.18 ? 329 PRO B CD 1 ATOM 2417 N N . ALA B 1 115 ? 28.614 34.741 38.184 1.00 129.83 ? 330 ALA B N 1 ATOM 2418 C CA . ALA B 1 115 ? 29.125 35.370 36.972 1.00 128.10 ? 330 ALA B CA 1 ATOM 2419 C C . ALA B 1 115 ? 29.650 34.247 36.080 1.00 126.83 ? 330 ALA B C 1 ATOM 2420 O O . ALA B 1 115 ? 30.862 34.064 35.946 1.00 126.45 ? 330 ALA B O 1 ATOM 2421 C CB . ALA B 1 115 ? 30.253 36.343 37.315 1.00 127.57 ? 330 ALA B CB 1 ATOM 2422 N N . PRO B 1 116 ? 28.733 33.477 35.463 1.00 125.66 ? 331 PRO B N 1 ATOM 2423 C CA . PRO B 1 116 ? 29.057 32.354 34.575 1.00 124.03 ? 331 PRO B CA 1 ATOM 2424 C C . PRO B 1 116 ? 30.382 32.508 33.817 1.00 121.96 ? 331 PRO B C 1 ATOM 2425 O O . PRO B 1 116 ? 30.461 33.207 32.804 1.00 122.14 ? 331 PRO B O 1 ATOM 2426 C CB . PRO B 1 116 ? 27.841 32.302 33.657 1.00 124.73 ? 331 PRO B CB 1 ATOM 2427 C CG . PRO B 1 116 ? 26.730 32.613 34.611 1.00 124.64 ? 331 PRO B CG 1 ATOM 2428 C CD . PRO B 1 116 ? 27.290 33.787 35.395 1.00 125.24 ? 331 PRO B CD 1 ATOM 2429 N N . ILE B 1 117 ? 31.413 31.837 34.328 1.00 119.19 ? 332 ILE B N 1 ATOM 2430 C CA . ILE B 1 117 ? 32.762 31.867 33.763 1.00 116.44 ? 332 ILE B CA 1 ATOM 2431 C C . ILE B 1 117 ? 32.806 31.865 32.231 1.00 114.45 ? 332 ILE B C 1 ATOM 2432 O O . ILE B 1 117 ? 32.044 31.147 31.574 1.00 114.04 ? 332 ILE B O 1 ATOM 2433 C CB . ILE B 1 117 ? 33.594 30.659 34.271 1.00 116.53 ? 332 ILE B CB 1 ATOM 2434 C CG1 . ILE B 1 117 ? 33.350 30.446 35.767 1.00 116.42 ? 332 ILE B CG1 1 ATOM 2435 C CG2 . ILE B 1 117 ? 35.082 30.905 34.024 1.00 115.86 ? 332 ILE B CG2 1 ATOM 2436 C CD1 . ILE B 1 117 ? 33.965 29.171 36.314 1.00 116.54 ? 332 ILE B CD1 1 ATOM 2437 N N . GLU B 1 118 ? 33.701 32.680 31.673 1.00 111.54 ? 333 GLU B N 1 ATOM 2438 C CA . GLU B 1 118 ? 33.881 32.769 30.226 1.00 108.53 ? 333 GLU B CA 1 ATOM 2439 C C . GLU B 1 118 ? 35.315 32.422 29.863 1.00 106.02 ? 333 GLU B C 1 ATOM 2440 O O . GLU B 1 118 ? 36.197 32.402 30.724 1.00 105.79 ? 333 GLU B O 1 ATOM 2441 C CB . GLU B 1 118 ? 33.573 34.174 29.710 1.00 108.41 ? 333 GLU B CB 1 ATOM 2442 C CG . GLU B 1 118 ? 32.114 34.559 29.775 1.00 109.57 ? 333 GLU B CG 1 ATOM 2443 C CD . GLU B 1 118 ? 31.791 35.727 28.867 1.00 110.46 ? 333 GLU B CD 1 ATOM 2444 O OE1 . GLU B 1 118 ? 32.489 36.761 28.951 1.00 110.62 ? 333 GLU B OE1 1 ATOM 2445 O OE2 . GLU B 1 118 ? 30.836 35.613 28.068 1.00 110.96 ? 333 GLU B OE2 1 ATOM 2446 N N . LYS B 1 119 ? 35.545 32.148 28.585 1.00 102.50 ? 334 LYS B N 1 ATOM 2447 C CA . LYS B 1 119 ? 36.879 31.809 28.117 1.00 98.33 ? 334 LYS B CA 1 ATOM 2448 C C . LYS B 1 119 ? 37.078 32.296 26.689 1.00 96.51 ? 334 LYS B C 1 ATOM 2449 O O . LYS B 1 119 ? 36.130 32.361 25.901 1.00 94.92 ? 334 LYS B O 1 ATOM 2450 C CB . LYS B 1 119 ? 37.094 30.298 28.183 1.00 97.28 ? 334 LYS B CB 1 ATOM 2451 C CG . LYS B 1 119 ? 36.976 29.699 29.576 1.00 95.49 ? 334 LYS B CG 1 ATOM 2452 C CD . LYS B 1 119 ? 38.149 30.068 30.470 1.00 94.29 ? 334 LYS B CD 1 ATOM 2453 C CE . LYS B 1 119 ? 38.062 29.319 31.799 1.00 94.13 ? 334 LYS B CE 1 ATOM 2454 N NZ . LYS B 1 119 ? 39.238 29.537 32.690 1.00 92.29 ? 334 LYS B NZ 1 ATOM 2455 N N . THR B 1 120 ? 38.323 32.639 26.372 1.00 94.70 ? 335 THR B N 1 ATOM 2456 C CA . THR B 1 120 ? 38.691 33.124 25.046 1.00 92.34 ? 335 THR B CA 1 ATOM 2457 C C . THR B 1 120 ? 40.014 32.490 24.625 1.00 89.48 ? 335 THR B C 1 ATOM 2458 O O . THR B 1 120 ? 40.915 32.332 25.450 1.00 89.37 ? 335 THR B O 1 ATOM 2459 C CB . THR B 1 120 ? 38.857 34.663 25.049 1.00 93.82 ? 335 THR B CB 1 ATOM 2460 O OG1 . THR B 1 120 ? 37.636 35.277 25.486 1.00 95.26 ? 335 THR B OG1 1 ATOM 2461 C CG2 . THR B 1 120 ? 39.208 35.173 23.653 1.00 93.67 ? 335 THR B CG2 1 ATOM 2462 N N . ILE B 1 121 ? 40.122 32.109 23.352 1.00 86.29 ? 336 ILE B N 1 ATOM 2463 C CA . ILE B 1 121 ? 41.354 31.512 22.827 1.00 83.01 ? 336 ILE B CA 1 ATOM 2464 C C . ILE B 1 121 ? 41.516 31.811 21.335 1.00 80.97 ? 336 ILE B C 1 ATOM 2465 O O . ILE B 1 121 ? 40.528 31.935 20.607 1.00 81.21 ? 336 ILE B O 1 ATOM 2466 C CB . ILE B 1 121 ? 41.385 29.979 23.020 1.00 82.77 ? 336 ILE B CB 1 ATOM 2467 C CG1 . ILE B 1 121 ? 40.490 29.294 21.994 1.00 81.42 ? 336 ILE B CG1 1 ATOM 2468 C CG2 . ILE B 1 121 ? 40.900 29.618 24.414 1.00 84.71 ? 336 ILE B CG2 1 ATOM 2469 C CD1 . ILE B 1 121 ? 40.626 27.797 21.997 1.00 80.69 ? 336 ILE B CD1 1 ATOM 2470 N N . SER B 1 122 ? 42.762 31.927 20.883 1.00 77.45 ? 337 SER B N 1 ATOM 2471 C CA . SER B 1 122 ? 43.046 32.212 19.476 1.00 74.15 ? 337 SER B CA 1 ATOM 2472 C C . SER B 1 122 ? 44.414 31.655 19.133 1.00 72.03 ? 337 SER B C 1 ATOM 2473 O O . SER B 1 122 ? 45.142 31.219 20.025 1.00 72.38 ? 337 SER B O 1 ATOM 2474 C CB . SER B 1 122 ? 43.056 33.719 19.227 1.00 74.16 ? 337 SER B CB 1 ATOM 2475 O OG . SER B 1 122 ? 44.196 34.323 19.818 1.00 72.41 ? 337 SER B OG 1 ATOM 2476 N N . LYS B 1 123 ? 44.776 31.671 17.852 1.00 68.38 ? 338 LYS B N 1 ATOM 2477 C CA . LYS B 1 123 ? 46.085 31.160 17.474 1.00 65.04 ? 338 LYS B CA 1 ATOM 2478 C C . LYS B 1 123 ? 47.156 32.025 18.117 1.00 63.07 ? 338 LYS B C 1 ATOM 2479 O O . LYS B 1 123 ? 46.908 33.176 18.474 1.00 63.31 ? 338 LYS B O 1 ATOM 2480 C CB . LYS B 1 123 ? 46.278 31.162 15.955 1.00 64.60 ? 338 LYS B CB 1 ATOM 2481 C CG . LYS B 1 123 ? 47.552 30.430 15.527 1.00 63.13 ? 338 LYS B CG 1 ATOM 2482 C CD . LYS B 1 123 ? 47.800 30.481 14.030 1.00 62.15 ? 338 LYS B CD 1 ATOM 2483 C CE . LYS B 1 123 ? 48.270 31.854 13.589 1.00 62.24 ? 338 LYS B CE 1 ATOM 2484 N NZ . LYS B 1 123 ? 48.710 31.881 12.172 1.00 60.38 ? 338 LYS B NZ 1 ATOM 2485 N N . ALA B 1 124 ? 48.349 31.467 18.264 1.00 61.50 ? 339 ALA B N 1 ATOM 2486 C CA . ALA B 1 124 ? 49.457 32.190 18.867 1.00 60.03 ? 339 ALA B CA 1 ATOM 2487 C C . ALA B 1 124 ? 49.924 33.355 17.996 1.00 59.50 ? 339 ALA B C 1 ATOM 2488 O O . ALA B 1 124 ? 49.998 33.240 16.774 1.00 59.51 ? 339 ALA B O 1 ATOM 2489 C CB . ALA B 1 124 ? 50.609 31.235 19.116 1.00 59.79 ? 339 ALA B CB 1 ATOM 2490 N N . LYS B 1 125 ? 50.239 34.478 18.633 1.00 58.81 ? 340 LYS B N 1 ATOM 2491 C CA . LYS B 1 125 ? 50.717 35.658 17.917 1.00 57.99 ? 340 LYS B CA 1 ATOM 2492 C C . LYS B 1 125 ? 52.193 35.459 17.597 1.00 56.48 ? 340 LYS B C 1 ATOM 2493 O O . LYS B 1 125 ? 52.852 34.604 18.174 1.00 55.72 ? 340 LYS B O 1 ATOM 2494 C CB . LYS B 1 125 ? 50.595 36.915 18.788 1.00 59.62 ? 340 LYS B CB 1 ATOM 2495 C CG . LYS B 1 125 ? 49.245 37.156 19.441 1.00 61.44 ? 340 LYS B CG 1 ATOM 2496 C CD . LYS B 1 125 ? 48.174 37.463 18.424 1.00 64.64 ? 340 LYS B CD 1 ATOM 2497 C CE . LYS B 1 125 ? 46.889 37.838 19.125 1.00 66.98 ? 340 LYS B CE 1 ATOM 2498 N NZ . LYS B 1 125 ? 47.122 38.973 20.060 1.00 67.68 ? 340 LYS B NZ 1 ATOM 2499 N N . GLY B 1 126 ? 52.719 36.253 16.679 1.00 55.11 ? 341 GLY B N 1 ATOM 2500 C CA . GLY B 1 126 ? 54.127 36.134 16.378 1.00 53.47 ? 341 GLY B CA 1 ATOM 2501 C C . GLY B 1 126 ? 54.449 35.576 15.020 1.00 52.52 ? 341 GLY B C 1 ATOM 2502 O O . GLY B 1 126 ? 53.818 34.632 14.564 1.00 53.17 ? 341 GLY B O 1 ATOM 2503 N N . GLN B 1 127 ? 55.453 36.177 14.392 1.00 51.60 ? 342 GLN B N 1 ATOM 2504 C CA . GLN B 1 127 ? 55.936 35.796 13.071 1.00 50.46 ? 342 GLN B CA 1 ATOM 2505 C C . GLN B 1 127 ? 56.158 34.294 12.957 1.00 48.19 ? 342 GLN B C 1 ATOM 2506 O O . GLN B 1 127 ? 57.090 33.759 13.543 1.00 48.75 ? 342 GLN B O 1 ATOM 2507 C CB . GLN B 1 127 ? 57.253 36.556 12.790 1.00 52.68 ? 342 GLN B CB 1 ATOM 2508 C CG . GLN B 1 127 ? 58.129 36.023 11.651 1.00 55.09 ? 342 GLN B CG 1 ATOM 2509 C CD . GLN B 1 127 ? 57.595 36.346 10.267 1.00 56.43 ? 342 GLN B CD 1 ATOM 2510 O OE1 . GLN B 1 127 ? 56.489 35.955 9.902 1.00 57.41 ? 342 GLN B OE1 1 ATOM 2511 N NE2 . GLN B 1 127 ? 58.390 37.060 9.486 1.00 58.50 ? 342 GLN B NE2 1 ATOM 2512 N N . PRO B 1 128 ? 55.294 33.591 12.210 1.00 46.86 ? 343 PRO B N 1 ATOM 2513 C CA . PRO B 1 128 ? 55.453 32.144 12.051 1.00 47.69 ? 343 PRO B CA 1 ATOM 2514 C C . PRO B 1 128 ? 56.878 31.818 11.626 1.00 49.15 ? 343 PRO B C 1 ATOM 2515 O O . PRO B 1 128 ? 57.565 32.658 11.049 1.00 50.44 ? 343 PRO B O 1 ATOM 2516 C CB . PRO B 1 128 ? 54.443 31.808 10.963 1.00 46.03 ? 343 PRO B CB 1 ATOM 2517 C CG . PRO B 1 128 ? 53.331 32.757 11.254 1.00 46.18 ? 343 PRO B CG 1 ATOM 2518 C CD . PRO B 1 128 ? 54.076 34.058 11.528 1.00 46.99 ? 343 PRO B CD 1 ATOM 2519 N N . ARG B 1 129 ? 57.321 30.601 11.915 1.00 49.53 ? 344 ARG B N 1 ATOM 2520 C CA . ARG B 1 129 ? 58.669 30.174 11.561 1.00 48.95 ? 344 ARG B CA 1 ATOM 2521 C C . ARG B 1 129 ? 58.623 28.733 11.059 1.00 47.32 ? 344 ARG B C 1 ATOM 2522 O O . ARG B 1 129 ? 57.918 27.896 11.614 1.00 47.21 ? 344 ARG B O 1 ATOM 2523 C CB . ARG B 1 129 ? 59.574 30.298 12.784 1.00 51.14 ? 344 ARG B CB 1 ATOM 2524 C CG . ARG B 1 129 ? 60.643 31.363 12.674 1.00 54.03 ? 344 ARG B CG 1 ATOM 2525 C CD . ARG B 1 129 ? 61.170 31.735 14.053 1.00 56.81 ? 344 ARG B CD 1 ATOM 2526 N NE . ARG B 1 129 ? 60.238 32.616 14.756 1.00 61.18 ? 344 ARG B NE 1 ATOM 2527 C CZ . ARG B 1 129 ? 60.311 32.913 16.053 1.00 63.02 ? 344 ARG B CZ 1 ATOM 2528 N NH1 . ARG B 1 129 ? 61.280 32.391 16.802 1.00 62.60 ? 344 ARG B NH1 1 ATOM 2529 N NH2 . ARG B 1 129 ? 59.419 33.738 16.600 1.00 63.01 ? 344 ARG B NH2 1 ATOM 2530 N N . GLU B 1 130 ? 59.380 28.448 10.005 1.00 46.67 ? 345 GLU B N 1 ATOM 2531 C CA . GLU B 1 130 ? 59.407 27.111 9.398 1.00 45.60 ? 345 GLU B CA 1 ATOM 2532 C C . GLU B 1 130 ? 60.262 26.085 10.125 1.00 44.16 ? 345 GLU B C 1 ATOM 2533 O O . GLU B 1 130 ? 61.430 26.330 10.433 1.00 44.07 ? 345 GLU B O 1 ATOM 2534 C CB . GLU B 1 130 ? 59.885 27.199 7.947 1.00 44.53 ? 345 GLU B CB 1 ATOM 2535 C CG . GLU B 1 130 ? 59.661 25.944 7.147 1.00 42.75 ? 345 GLU B CG 1 ATOM 2536 C CD . GLU B 1 130 ? 60.028 26.120 5.689 1.00 43.39 ? 345 GLU B CD 1 ATOM 2537 O OE1 . GLU B 1 130 ? 59.525 25.350 4.835 1.00 46.02 ? 345 GLU B OE1 1 ATOM 2538 O OE2 . GLU B 1 130 ? 60.827 27.026 5.393 1.00 43.46 ? 345 GLU B OE2 1 ATOM 2539 N N . PRO B 1 131 ? 59.680 24.911 10.401 1.00 43.20 ? 346 PRO B N 1 ATOM 2540 C CA . PRO B 1 131 ? 60.382 23.831 11.091 1.00 42.20 ? 346 PRO B CA 1 ATOM 2541 C C . PRO B 1 131 ? 61.384 23.139 10.183 1.00 41.82 ? 346 PRO B C 1 ATOM 2542 O O . PRO B 1 131 ? 61.169 23.049 8.983 1.00 41.27 ? 346 PRO B O 1 ATOM 2543 C CB . PRO B 1 131 ? 59.247 22.897 11.499 1.00 40.73 ? 346 PRO B CB 1 ATOM 2544 C CG . PRO B 1 131 ? 58.259 23.076 10.416 1.00 40.75 ? 346 PRO B CG 1 ATOM 2545 C CD . PRO B 1 131 ? 58.256 24.572 10.220 1.00 42.27 ? 346 PRO B CD 1 ATOM 2546 N N . GLN B 1 132 ? 62.491 22.685 10.757 1.00 41.65 ? 347 GLN B N 1 ATOM 2547 C CA . GLN B 1 132 ? 63.501 21.954 10.000 1.00 42.00 ? 347 GLN B CA 1 ATOM 2548 C C . GLN B 1 132 ? 63.361 20.559 10.575 1.00 41.02 ? 347 GLN B C 1 ATOM 2549 O O . GLN B 1 132 ? 63.312 20.389 11.794 1.00 42.12 ? 347 GLN B O 1 ATOM 2550 C CB . GLN B 1 132 ? 64.909 22.477 10.273 1.00 42.59 ? 347 GLN B CB 1 ATOM 2551 C CG . GLN B 1 132 ? 65.025 23.981 10.211 1.00 47.27 ? 347 GLN B CG 1 ATOM 2552 C CD . GLN B 1 132 ? 65.935 24.531 11.305 1.00 51.01 ? 347 GLN B CD 1 ATOM 2553 O OE1 . GLN B 1 132 ? 65.805 25.691 11.705 1.00 52.60 ? 347 GLN B OE1 1 ATOM 2554 N NE2 . GLN B 1 132 ? 66.862 23.700 11.792 1.00 51.19 ? 347 GLN B NE2 1 ATOM 2555 N N . VAL B 1 133 ? 63.290 19.568 9.700 1.00 38.03 ? 348 VAL B N 1 ATOM 2556 C CA . VAL B 1 133 ? 63.120 18.194 10.121 1.00 34.50 ? 348 VAL B CA 1 ATOM 2557 C C . VAL B 1 133 ? 64.394 17.383 9.973 1.00 34.14 ? 348 VAL B C 1 ATOM 2558 O O . VAL B 1 133 ? 64.984 17.355 8.897 1.00 34.33 ? 348 VAL B O 1 ATOM 2559 C CB . VAL B 1 133 ? 61.985 17.550 9.294 1.00 32.49 ? 348 VAL B CB 1 ATOM 2560 C CG1 . VAL B 1 133 ? 61.840 16.091 9.616 1.00 32.20 ? 348 VAL B CG1 1 ATOM 2561 C CG2 . VAL B 1 133 ? 60.696 18.266 9.581 1.00 31.80 ? 348 VAL B CG2 1 ATOM 2562 N N . TYR B 1 134 ? 64.811 16.726 11.057 1.00 34.74 ? 349 TYR B N 1 ATOM 2563 C CA . TYR B 1 134 ? 66.015 15.876 11.052 1.00 35.99 ? 349 TYR B CA 1 ATOM 2564 C C . TYR B 1 134 ? 65.754 14.451 11.574 1.00 35.77 ? 349 TYR B C 1 ATOM 2565 O O . TYR B 1 134 ? 65.318 14.264 12.714 1.00 37.38 ? 349 TYR B O 1 ATOM 2566 C CB . TYR B 1 134 ? 67.136 16.497 11.896 1.00 35.59 ? 349 TYR B CB 1 ATOM 2567 C CG . TYR B 1 134 ? 67.611 17.847 11.426 1.00 34.85 ? 349 TYR B CG 1 ATOM 2568 C CD1 . TYR B 1 134 ? 68.278 17.990 10.216 1.00 34.32 ? 349 TYR B CD1 1 ATOM 2569 C CD2 . TYR B 1 134 ? 67.372 18.990 12.191 1.00 32.76 ? 349 TYR B CD2 1 ATOM 2570 C CE1 . TYR B 1 134 ? 68.695 19.246 9.775 1.00 35.66 ? 349 TYR B CE1 1 ATOM 2571 C CE2 . TYR B 1 134 ? 67.779 20.241 11.767 1.00 33.38 ? 349 TYR B CE2 1 ATOM 2572 C CZ . TYR B 1 134 ? 68.442 20.370 10.556 1.00 35.87 ? 349 TYR B CZ 1 ATOM 2573 O OH . TYR B 1 134 ? 68.850 21.620 10.128 1.00 36.15 ? 349 TYR B OH 1 ATOM 2574 N N . THR B 1 135 ? 66.020 13.454 10.735 1.00 34.02 ? 350 THR B N 1 ATOM 2575 C CA . THR B 1 135 ? 65.848 12.062 11.126 1.00 33.77 ? 350 THR B CA 1 ATOM 2576 C C . THR B 1 135 ? 67.186 11.555 11.685 1.00 34.04 ? 350 THR B C 1 ATOM 2577 O O . THR B 1 135 ? 68.247 11.766 11.084 1.00 36.31 ? 350 THR B O 1 ATOM 2578 C CB . THR B 1 135 ? 65.414 11.168 9.927 1.00 34.10 ? 350 THR B CB 1 ATOM 2579 O OG1 . THR B 1 135 ? 66.454 11.104 8.942 1.00 34.47 ? 350 THR B OG1 1 ATOM 2580 C CG2 . THR B 1 135 ? 64.180 11.723 9.291 1.00 34.10 ? 350 THR B CG2 1 ATOM 2581 N N . LEU B 1 136 ? 67.125 10.889 12.836 1.00 32.21 ? 351 LEU B N 1 ATOM 2582 C CA . LEU B 1 136 ? 68.303 10.360 13.507 1.00 28.43 ? 351 LEU B CA 1 ATOM 2583 C C . LEU B 1 136 ? 68.231 8.843 13.629 1.00 27.18 ? 351 LEU B C 1 ATOM 2584 O O . LEU B 1 136 ? 67.268 8.309 14.151 1.00 29.64 ? 351 LEU B O 1 ATOM 2585 C CB . LEU B 1 136 ? 68.393 10.977 14.896 1.00 27.54 ? 351 LEU B CB 1 ATOM 2586 C CG . LEU B 1 136 ? 68.249 12.503 14.971 1.00 24.75 ? 351 LEU B CG 1 ATOM 2587 C CD1 . LEU B 1 136 ? 68.535 12.944 16.370 1.00 24.90 ? 351 LEU B CD1 1 ATOM 2588 C CD2 . LEU B 1 136 ? 69.209 13.189 14.044 1.00 25.21 ? 351 LEU B CD2 1 ATOM 2589 N N . PRO B 1 137 ? 69.246 8.130 13.139 1.00 25.18 ? 352 PRO B N 1 ATOM 2590 C CA . PRO B 1 137 ? 69.289 6.663 13.202 1.00 25.89 ? 352 PRO B CA 1 ATOM 2591 C C . PRO B 1 137 ? 69.503 6.152 14.621 1.00 27.05 ? 352 PRO B C 1 ATOM 2592 O O . PRO B 1 137 ? 69.937 6.899 15.489 1.00 29.87 ? 352 PRO B O 1 ATOM 2593 C CB . PRO B 1 137 ? 70.446 6.304 12.275 1.00 25.16 ? 352 PRO B CB 1 ATOM 2594 C CG . PRO B 1 137 ? 71.313 7.510 12.342 1.00 26.02 ? 352 PRO B CG 1 ATOM 2595 C CD . PRO B 1 137 ? 70.349 8.656 12.331 1.00 24.55 ? 352 PRO B CD 1 ATOM 2596 N N . PRO B 1 138 ? 69.210 4.869 14.876 1.00 26.61 ? 353 PRO B N 1 ATOM 2597 C CA . PRO B 1 138 ? 69.398 4.359 16.228 1.00 25.10 ? 353 PRO B CA 1 ATOM 2598 C C . PRO B 1 138 ? 70.856 4.441 16.559 1.00 25.86 ? 353 PRO B C 1 ATOM 2599 O O . PRO B 1 138 ? 71.685 4.396 15.659 1.00 26.00 ? 353 PRO B O 1 ATOM 2600 C CB . PRO B 1 138 ? 68.950 2.900 16.126 1.00 24.13 ? 353 PRO B CB 1 ATOM 2601 C CG . PRO B 1 138 ? 68.158 2.821 14.881 1.00 25.34 ? 353 PRO B CG 1 ATOM 2602 C CD . PRO B 1 138 ? 68.875 3.769 13.961 1.00 28.79 ? 353 PRO B CD 1 ATOM 2603 N N . SER B 1 139 ? 71.173 4.585 17.840 1.00 28.02 ? 354 SER B N 1 ATOM 2604 C CA . SER B 1 139 ? 72.561 4.598 18.258 1.00 27.64 ? 354 SER B CA 1 ATOM 2605 C C . SER B 1 139 ? 72.977 3.142 18.068 1.00 29.13 ? 354 SER B C 1 ATOM 2606 O O . SER B 1 139 ? 72.188 2.212 18.293 1.00 28.08 ? 354 SER B O 1 ATOM 2607 C CB . SER B 1 139 ? 72.685 4.992 19.716 1.00 28.72 ? 354 SER B CB 1 ATOM 2608 O OG . SER B 1 139 ? 73.910 4.524 20.251 1.00 30.26 ? 354 SER B OG 1 ATOM 2609 N N . ARG B 1 140 ? 74.219 2.947 17.657 1.00 30.12 ? 355 ARG B N 1 ATOM 2610 C CA . ARG B 1 140 ? 74.726 1.621 17.378 1.00 31.12 ? 355 ARG B CA 1 ATOM 2611 C C . ARG B 1 140 ? 74.672 0.609 18.509 1.00 32.37 ? 355 ARG B C 1 ATOM 2612 O O . ARG B 1 140 ? 74.631 -0.588 18.250 1.00 31.96 ? 355 ARG B O 1 ATOM 2613 C CB . ARG B 1 140 ? 76.141 1.739 16.848 1.00 31.64 ? 355 ARG B CB 1 ATOM 2614 C CG . ARG B 1 140 ? 76.807 0.432 16.551 1.00 33.70 ? 355 ARG B CG 1 ATOM 2615 C CD . ARG B 1 140 ? 76.079 -0.352 15.499 1.00 35.01 ? 355 ARG B CD 1 ATOM 2616 N NE . ARG B 1 140 ? 76.719 -1.652 15.355 1.00 38.73 ? 355 ARG B NE 1 ATOM 2617 C CZ . ARG B 1 140 ? 77.863 -1.848 14.715 1.00 37.10 ? 355 ARG B CZ 1 ATOM 2618 N NH1 . ARG B 1 140 ? 78.480 -0.819 14.145 1.00 34.57 ? 355 ARG B NH1 1 ATOM 2619 N NH2 . ARG B 1 140 ? 78.390 -3.069 14.670 1.00 35.17 ? 355 ARG B NH2 1 ATOM 2620 N N . ASP B 1 141 ? 74.676 1.059 19.757 1.00 33.79 ? 356 ASP B N 1 ATOM 2621 C CA . ASP B 1 141 ? 74.616 0.101 20.848 1.00 36.25 ? 356 ASP B CA 1 ATOM 2622 C C . ASP B 1 141 ? 73.185 -0.298 21.157 1.00 38.61 ? 356 ASP B C 1 ATOM 2623 O O . ASP B 1 141 ? 72.956 -1.289 21.860 1.00 40.82 ? 356 ASP B O 1 ATOM 2624 C CB . ASP B 1 141 ? 75.297 0.633 22.107 1.00 37.31 ? 356 ASP B CB 1 ATOM 2625 C CG . ASP B 1 141 ? 74.852 2.028 22.469 1.00 41.29 ? 356 ASP B CG 1 ATOM 2626 O OD1 . ASP B 1 141 ? 73.991 2.581 21.754 1.00 43.69 ? 356 ASP B OD1 1 ATOM 2627 O OD2 . ASP B 1 141 ? 75.370 2.576 23.471 1.00 41.78 ? 356 ASP B OD2 1 ATOM 2628 N N . GLU B 1 142 ? 72.213 0.452 20.637 1.00 39.10 ? 357 GLU B N 1 ATOM 2629 C CA . GLU B 1 142 ? 70.824 0.084 20.883 1.00 39.12 ? 357 GLU B CA 1 ATOM 2630 C C . GLU B 1 142 ? 70.502 -1.054 19.946 1.00 39.42 ? 357 GLU B C 1 ATOM 2631 O O . GLU B 1 142 ? 69.435 -1.655 20.023 1.00 40.38 ? 357 GLU B O 1 ATOM 2632 C CB . GLU B 1 142 ? 69.855 1.223 20.595 1.00 38.34 ? 357 GLU B CB 1 ATOM 2633 C CG . GLU B 1 142 ? 68.417 0.739 20.664 1.00 38.53 ? 357 GLU B CG 1 ATOM 2634 C CD . GLU B 1 142 ? 67.391 1.815 20.389 1.00 40.50 ? 357 GLU B CD 1 ATOM 2635 O OE1 . GLU B 1 142 ? 67.570 2.596 19.428 1.00 39.60 ? 357 GLU B OE1 1 ATOM 2636 O OE2 . GLU B 1 142 ? 66.390 1.864 21.134 1.00 41.17 ? 357 GLU B OE2 1 ATOM 2637 N N . LEU B 1 143 ? 71.442 -1.352 19.064 1.00 38.54 ? 358 LEU B N 1 ATOM 2638 C CA . LEU B 1 143 ? 71.239 -2.401 18.098 1.00 38.89 ? 358 LEU B CA 1 ATOM 2639 C C . LEU B 1 143 ? 71.397 -3.794 18.654 1.00 40.46 ? 358 LEU B C 1 ATOM 2640 O O . LEU B 1 143 ? 71.402 -4.749 17.887 1.00 42.70 ? 358 LEU B O 1 ATOM 2641 C CB . LEU B 1 143 ? 72.184 -2.210 16.931 1.00 40.07 ? 358 LEU B CB 1 ATOM 2642 C CG . LEU B 1 143 ? 71.533 -1.937 15.585 1.00 40.22 ? 358 LEU B CG 1 ATOM 2643 C CD1 . LEU B 1 143 ? 70.573 -0.795 15.695 1.00 39.02 ? 358 LEU B CD1 1 ATOM 2644 C CD2 . LEU B 1 143 ? 72.623 -1.620 14.577 1.00 42.65 ? 358 LEU B CD2 1 ATOM 2645 N N . THR B 1 144 ? 71.545 -3.930 19.970 1.00 40.82 ? 359 THR B N 1 ATOM 2646 C CA . THR B 1 144 ? 71.659 -5.265 20.561 1.00 41.33 ? 359 THR B CA 1 ATOM 2647 C C . THR B 1 144 ? 70.318 -5.643 21.177 1.00 40.33 ? 359 THR B C 1 ATOM 2648 O O . THR B 1 144 ? 70.102 -6.782 21.589 1.00 40.22 ? 359 THR B O 1 ATOM 2649 C CB . THR B 1 144 ? 72.784 -5.358 21.622 1.00 42.88 ? 359 THR B CB 1 ATOM 2650 O OG1 . THR B 1 144 ? 72.568 -4.390 22.662 1.00 45.83 ? 359 THR B OG1 1 ATOM 2651 C CG2 . THR B 1 144 ? 74.147 -5.134 20.960 1.00 41.92 ? 359 THR B CG2 1 ATOM 2652 N N . LYS B 1 145 ? 69.421 -4.665 21.241 1.00 40.43 ? 360 LYS B N 1 ATOM 2653 C CA . LYS B 1 145 ? 68.063 -4.885 21.732 1.00 40.10 ? 360 LYS B CA 1 ATOM 2654 C C . LYS B 1 145 ? 67.320 -5.415 20.498 1.00 39.40 ? 360 LYS B C 1 ATOM 2655 O O . LYS B 1 145 ? 67.800 -5.237 19.376 1.00 37.53 ? 360 LYS B O 1 ATOM 2656 C CB . LYS B 1 145 ? 67.433 -3.568 22.192 1.00 40.22 ? 360 LYS B CB 1 ATOM 2657 C CG . LYS B 1 145 ? 67.644 -3.230 23.658 1.00 40.45 ? 360 LYS B CG 1 ATOM 2658 C CD . LYS B 1 145 ? 69.096 -3.002 23.986 1.00 42.62 ? 360 LYS B CD 1 ATOM 2659 C CE . LYS B 1 145 ? 69.258 -2.571 25.441 1.00 45.60 ? 360 LYS B CE 1 ATOM 2660 N NZ . LYS B 1 145 ? 68.863 -3.623 26.434 1.00 45.99 ? 360 LYS B NZ 1 ATOM 2661 N N . ASN B 1 146 ? 66.175 -6.069 20.675 1.00 38.83 ? 361 ASN B N 1 ATOM 2662 C CA . ASN B 1 146 ? 65.478 -6.578 19.498 1.00 41.41 ? 361 ASN B CA 1 ATOM 2663 C C . ASN B 1 146 ? 64.488 -5.584 18.930 1.00 38.51 ? 361 ASN B C 1 ATOM 2664 O O . ASN B 1 146 ? 63.637 -5.939 18.132 1.00 37.79 ? 361 ASN B O 1 ATOM 2665 C CB . ASN B 1 146 ? 64.780 -7.906 19.778 1.00 47.34 ? 361 ASN B CB 1 ATOM 2666 C CG . ASN B 1 146 ? 63.835 -7.823 20.936 1.00 54.09 ? 361 ASN B CG 1 ATOM 2667 O OD1 . ASN B 1 146 ? 64.144 -8.292 22.043 1.00 57.56 ? 361 ASN B OD1 1 ATOM 2668 N ND2 . ASN B 1 146 ? 62.669 -7.209 20.707 1.00 55.48 ? 361 ASN B ND2 1 ATOM 2669 N N . GLN B 1 147 ? 64.633 -4.332 19.349 1.00 37.04 ? 362 GLN B N 1 ATOM 2670 C CA . GLN B 1 147 ? 63.824 -3.225 18.867 1.00 34.13 ? 362 GLN B CA 1 ATOM 2671 C C . GLN B 1 147 ? 64.648 -1.944 18.916 1.00 32.72 ? 362 GLN B C 1 ATOM 2672 O O . GLN B 1 147 ? 65.322 -1.680 19.906 1.00 35.27 ? 362 GLN B O 1 ATOM 2673 C CB . GLN B 1 147 ? 62.584 -3.076 19.716 1.00 33.43 ? 362 GLN B CB 1 ATOM 2674 C CG . GLN B 1 147 ? 61.662 -4.226 19.558 1.00 35.81 ? 362 GLN B CG 1 ATOM 2675 C CD . GLN B 1 147 ? 60.244 -3.835 19.802 1.00 36.85 ? 362 GLN B CD 1 ATOM 2676 O OE1 . GLN B 1 147 ? 59.851 -3.531 20.935 1.00 37.24 ? 362 GLN B OE1 1 ATOM 2677 N NE2 . GLN B 1 147 ? 59.453 -3.819 18.735 1.00 38.09 ? 362 GLN B NE2 1 ATOM 2678 N N . VAL B 1 148 ? 64.603 -1.150 17.853 1.00 29.70 ? 363 VAL B N 1 ATOM 2679 C CA . VAL B 1 148 ? 65.358 0.096 17.817 1.00 28.21 ? 363 VAL B CA 1 ATOM 2680 C C . VAL B 1 148 ? 64.520 1.363 17.744 1.00 28.74 ? 363 VAL B C 1 ATOM 2681 O O . VAL B 1 148 ? 63.318 1.328 17.455 1.00 28.03 ? 363 VAL B O 1 ATOM 2682 C CB . VAL B 1 148 ? 66.353 0.128 16.646 1.00 27.67 ? 363 VAL B CB 1 ATOM 2683 C CG1 . VAL B 1 148 ? 67.440 -0.874 16.889 1.00 28.71 ? 363 VAL B CG1 1 ATOM 2684 C CG2 . VAL B 1 148 ? 65.647 -0.161 15.336 1.00 26.46 ? 363 VAL B CG2 1 ATOM 2685 N N . SER B 1 149 ? 65.181 2.486 18.012 1.00 26.69 ? 364 SER B N 1 ATOM 2686 C CA . SER B 1 149 ? 64.542 3.779 17.998 1.00 24.64 ? 364 SER B CA 1 ATOM 2687 C C . SER B 1 149 ? 64.937 4.579 16.789 1.00 27.49 ? 364 SER B C 1 ATOM 2688 O O . SER B 1 149 ? 66.115 4.731 16.475 1.00 30.94 ? 364 SER B O 1 ATOM 2689 C CB . SER B 1 149 ? 64.924 4.562 19.232 1.00 21.66 ? 364 SER B CB 1 ATOM 2690 O OG . SER B 1 149 ? 64.470 3.901 20.388 1.00 24.48 ? 364 SER B OG 1 ATOM 2691 N N . LEU B 1 150 ? 63.941 5.079 16.085 1.00 27.67 ? 365 LEU B N 1 ATOM 2692 C CA . LEU B 1 150 ? 64.204 5.908 14.936 1.00 27.33 ? 365 LEU B CA 1 ATOM 2693 C C . LEU B 1 150 ? 63.700 7.214 15.488 1.00 28.22 ? 365 LEU B C 1 ATOM 2694 O O . LEU B 1 150 ? 62.555 7.286 15.921 1.00 31.17 ? 365 LEU B O 1 ATOM 2695 C CB . LEU B 1 150 ? 63.377 5.426 13.744 1.00 25.72 ? 365 LEU B CB 1 ATOM 2696 C CG . LEU B 1 150 ? 63.672 3.980 13.309 1.00 25.31 ? 365 LEU B CG 1 ATOM 2697 C CD1 . LEU B 1 150 ? 63.234 3.782 11.865 1.00 25.04 ? 365 LEU B CD1 1 ATOM 2698 C CD2 . LEU B 1 150 ? 65.162 3.700 13.414 1.00 21.02 ? 365 LEU B CD2 1 ATOM 2699 N N . THR B 1 151 ? 64.538 8.239 15.541 1.00 27.94 ? 366 THR B N 1 ATOM 2700 C CA . THR B 1 151 ? 64.040 9.476 16.101 1.00 29.06 ? 366 THR B CA 1 ATOM 2701 C C . THR B 1 151 ? 63.961 10.592 15.090 1.00 28.86 ? 366 THR B C 1 ATOM 2702 O O . THR B 1 151 ? 64.792 10.705 14.212 1.00 26.00 ? 366 THR B O 1 ATOM 2703 C CB . THR B 1 151 ? 64.864 9.950 17.324 1.00 30.67 ? 366 THR B CB 1 ATOM 2704 O OG1 . THR B 1 151 ? 65.509 11.177 16.998 1.00 35.97 ? 366 THR B OG1 1 ATOM 2705 C CG2 . THR B 1 151 ? 65.912 8.928 17.741 1.00 28.46 ? 366 THR B CG2 1 ATOM 2706 N N . CYS B 1 152 ? 62.924 11.409 15.236 1.00 32.64 ? 367 CYS B N 1 ATOM 2707 C CA . CYS B 1 152 ? 62.663 12.548 14.356 1.00 34.18 ? 367 CYS B CA 1 ATOM 2708 C C . CYS B 1 152 ? 62.683 13.874 15.123 1.00 33.40 ? 367 CYS B C 1 ATOM 2709 O O . CYS B 1 152 ? 61.798 14.122 15.957 1.00 32.61 ? 367 CYS B O 1 ATOM 2710 C CB . CYS B 1 152 ? 61.292 12.391 13.694 1.00 35.56 ? 367 CYS B CB 1 ATOM 2711 S SG . CYS B 1 152 ? 60.900 13.680 12.473 1.00 38.70 ? 367 CYS B SG 1 ATOM 2712 N N . LEU B 1 153 ? 63.689 14.706 14.830 1.00 30.47 ? 368 LEU B N 1 ATOM 2713 C CA . LEU B 1 153 ? 63.855 16.014 15.464 1.00 30.19 ? 368 LEU B CA 1 ATOM 2714 C C . LEU B 1 153 ? 63.151 17.096 14.652 1.00 29.85 ? 368 LEU B C 1 ATOM 2715 O O . LEU B 1 153 ? 63.452 17.267 13.475 1.00 31.60 ? 368 LEU B O 1 ATOM 2716 C CB . LEU B 1 153 ? 65.348 16.352 15.578 1.00 30.01 ? 368 LEU B CB 1 ATOM 2717 C CG . LEU B 1 153 ? 65.771 17.768 16.012 1.00 30.02 ? 368 LEU B CG 1 ATOM 2718 C CD1 . LEU B 1 153 ? 65.143 18.121 17.330 1.00 29.78 ? 368 LEU B CD1 1 ATOM 2719 C CD2 . LEU B 1 153 ? 67.273 17.847 16.139 1.00 29.28 ? 368 LEU B CD2 1 ATOM 2720 N N . VAL B 1 154 ? 62.222 17.824 15.264 1.00 27.35 ? 369 VAL B N 1 ATOM 2721 C CA . VAL B 1 154 ? 61.504 18.882 14.543 1.00 29.23 ? 369 VAL B CA 1 ATOM 2722 C C . VAL B 1 154 ? 61.764 20.192 15.265 1.00 30.46 ? 369 VAL B C 1 ATOM 2723 O O . VAL B 1 154 ? 61.208 20.438 16.327 1.00 32.46 ? 369 VAL B O 1 ATOM 2724 C CB . VAL B 1 154 ? 59.975 18.589 14.499 1.00 28.83 ? 369 VAL B CB 1 ATOM 2725 C CG1 . VAL B 1 154 ? 59.245 19.645 13.679 1.00 22.66 ? 369 VAL B CG1 1 ATOM 2726 C CG2 . VAL B 1 154 ? 59.741 17.199 13.916 1.00 29.54 ? 369 VAL B CG2 1 ATOM 2727 N N . LYS B 1 155 ? 62.606 21.044 14.699 1.00 31.01 ? 370 LYS B N 1 ATOM 2728 C CA . LYS B 1 155 ? 62.934 22.269 15.406 1.00 33.36 ? 370 LYS B CA 1 ATOM 2729 C C . LYS B 1 155 ? 62.750 23.592 14.694 1.00 35.73 ? 370 LYS B C 1 ATOM 2730 O O . LYS B 1 155 ? 62.509 23.667 13.483 1.00 36.26 ? 370 LYS B O 1 ATOM 2731 C CB . LYS B 1 155 ? 64.375 22.210 15.903 1.00 33.11 ? 370 LYS B CB 1 ATOM 2732 C CG . LYS B 1 155 ? 65.380 22.064 14.780 1.00 36.75 ? 370 LYS B CG 1 ATOM 2733 C CD . LYS B 1 155 ? 66.791 22.417 15.213 1.00 38.36 ? 370 LYS B CD 1 ATOM 2734 C CE . LYS B 1 155 ? 66.934 23.905 15.478 1.00 40.71 ? 370 LYS B CE 1 ATOM 2735 N NZ . LYS B 1 155 ? 68.309 24.224 15.953 1.00 42.61 ? 370 LYS B NZ 1 ATOM 2736 N N . GLY B 1 156 ? 62.877 24.643 15.491 1.00 35.50 ? 371 GLY B N 1 ATOM 2737 C CA . GLY B 1 156 ? 62.758 25.983 14.980 1.00 34.84 ? 371 GLY B CA 1 ATOM 2738 C C . GLY B 1 156 ? 61.402 26.356 14.456 1.00 34.64 ? 371 GLY B C 1 ATOM 2739 O O . GLY B 1 156 ? 61.322 27.178 13.560 1.00 36.00 ? 371 GLY B O 1 ATOM 2740 N N . PHE B 1 157 ? 60.331 25.778 14.985 1.00 35.41 ? 372 PHE B N 1 ATOM 2741 C CA . PHE B 1 157 ? 59.025 26.168 14.473 1.00 36.07 ? 372 PHE B CA 1 ATOM 2742 C C . PHE B 1 157 ? 58.229 27.056 15.405 1.00 36.79 ? 372 PHE B C 1 ATOM 2743 O O . PHE B 1 157 ? 58.432 27.069 16.619 1.00 38.32 ? 372 PHE B O 1 ATOM 2744 C CB . PHE B 1 157 ? 58.175 24.954 14.101 1.00 36.04 ? 372 PHE B CB 1 ATOM 2745 C CG . PHE B 1 157 ? 57.869 24.037 15.252 1.00 36.60 ? 372 PHE B CG 1 ATOM 2746 C CD1 . PHE B 1 157 ? 58.594 22.872 15.438 1.00 34.87 ? 372 PHE B CD1 1 ATOM 2747 C CD2 . PHE B 1 157 ? 56.851 24.335 16.146 1.00 37.43 ? 372 PHE B CD2 1 ATOM 2748 C CE1 . PHE B 1 157 ? 58.309 22.030 16.487 1.00 34.13 ? 372 PHE B CE1 1 ATOM 2749 C CE2 . PHE B 1 157 ? 56.568 23.490 17.200 1.00 36.00 ? 372 PHE B CE2 1 ATOM 2750 C CZ . PHE B 1 157 ? 57.301 22.337 17.367 1.00 33.76 ? 372 PHE B CZ 1 ATOM 2751 N N . TYR B 1 158 ? 57.322 27.812 14.807 1.00 36.80 ? 373 TYR B N 1 ATOM 2752 C CA . TYR B 1 158 ? 56.448 28.704 15.541 1.00 36.84 ? 373 TYR B CA 1 ATOM 2753 C C . TYR B 1 158 ? 55.325 29.022 14.590 1.00 37.06 ? 373 TYR B C 1 ATOM 2754 O O . TYR B 1 158 ? 55.578 29.338 13.429 1.00 38.36 ? 373 TYR B O 1 ATOM 2755 C CB . TYR B 1 158 ? 57.159 29.998 15.921 1.00 36.95 ? 373 TYR B CB 1 ATOM 2756 C CG . TYR B 1 158 ? 56.343 30.844 16.867 1.00 37.75 ? 373 TYR B CG 1 ATOM 2757 C CD1 . TYR B 1 158 ? 55.084 31.316 16.498 1.00 38.32 ? 373 TYR B CD1 1 ATOM 2758 C CD2 . TYR B 1 158 ? 56.801 31.127 18.153 1.00 38.29 ? 373 TYR B CD2 1 ATOM 2759 C CE1 . TYR B 1 158 ? 54.306 32.037 17.383 1.00 38.20 ? 373 TYR B CE1 1 ATOM 2760 C CE2 . TYR B 1 158 ? 56.027 31.849 19.044 1.00 37.08 ? 373 TYR B CE2 1 ATOM 2761 C CZ . TYR B 1 158 ? 54.783 32.296 18.649 1.00 37.28 ? 373 TYR B CZ 1 ATOM 2762 O OH . TYR B 1 158 ? 54.003 32.993 19.522 1.00 39.72 ? 373 TYR B OH 1 ATOM 2763 N N . PRO B 1 159 ? 54.071 28.962 15.069 1.00 35.69 ? 374 PRO B N 1 ATOM 2764 C CA . PRO B 1 159 ? 53.740 28.609 16.445 1.00 35.93 ? 374 PRO B CA 1 ATOM 2765 C C . PRO B 1 159 ? 53.929 27.119 16.750 1.00 37.51 ? 374 PRO B C 1 ATOM 2766 O O . PRO B 1 159 ? 54.389 26.348 15.899 1.00 36.26 ? 374 PRO B O 1 ATOM 2767 C CB . PRO B 1 159 ? 52.297 29.070 16.560 1.00 34.62 ? 374 PRO B CB 1 ATOM 2768 C CG . PRO B 1 159 ? 51.767 28.756 15.235 1.00 34.85 ? 374 PRO B CG 1 ATOM 2769 C CD . PRO B 1 159 ? 52.845 29.272 14.317 1.00 34.28 ? 374 PRO B CD 1 ATOM 2770 N N . SER B 1 160 ? 53.570 26.722 17.969 1.00 38.00 ? 375 SER B N 1 ATOM 2771 C CA . SER B 1 160 ? 53.723 25.339 18.396 1.00 39.17 ? 375 SER B CA 1 ATOM 2772 C C . SER B 1 160 ? 52.718 24.346 17.795 1.00 40.74 ? 375 SER B C 1 ATOM 2773 O O . SER B 1 160 ? 52.910 23.129 17.921 1.00 41.12 ? 375 SER B O 1 ATOM 2774 C CB . SER B 1 160 ? 53.681 25.263 19.928 1.00 38.05 ? 375 SER B CB 1 ATOM 2775 O OG . SER B 1 160 ? 52.413 25.613 20.438 1.00 35.58 ? 375 SER B OG 1 ATOM 2776 N N . ASP B 1 161 ? 51.653 24.843 17.157 1.00 40.32 ? 376 ASP B N 1 ATOM 2777 C CA . ASP B 1 161 ? 50.661 23.950 16.552 1.00 39.67 ? 376 ASP B CA 1 ATOM 2778 C C . ASP B 1 161 ? 51.377 23.131 15.515 1.00 36.73 ? 376 ASP B C 1 ATOM 2779 O O . ASP B 1 161 ? 51.939 23.690 14.586 1.00 35.67 ? 376 ASP B O 1 ATOM 2780 C CB . ASP B 1 161 ? 49.559 24.728 15.839 1.00 45.83 ? 376 ASP B CB 1 ATOM 2781 C CG . ASP B 1 161 ? 48.589 25.380 16.788 1.00 50.63 ? 376 ASP B CG 1 ATOM 2782 O OD1 . ASP B 1 161 ? 47.879 24.642 17.499 1.00 51.79 ? 376 ASP B OD1 1 ATOM 2783 O OD2 . ASP B 1 161 ? 48.535 26.633 16.816 1.00 54.49 ? 376 ASP B OD2 1 ATOM 2784 N N . ILE B 1 162 ? 51.348 21.814 15.651 1.00 34.65 ? 377 ILE B N 1 ATOM 2785 C CA . ILE B 1 162 ? 52.028 20.966 14.683 1.00 33.10 ? 377 ILE B CA 1 ATOM 2786 C C . ILE B 1 162 ? 51.548 19.504 14.738 1.00 33.75 ? 377 ILE B C 1 ATOM 2787 O O . ILE B 1 162 ? 50.974 19.051 15.735 1.00 33.35 ? 377 ILE B O 1 ATOM 2788 C CB . ILE B 1 162 ? 53.557 21.045 14.908 1.00 32.53 ? 377 ILE B CB 1 ATOM 2789 C CG1 . ILE B 1 162 ? 54.295 20.433 13.727 1.00 36.11 ? 377 ILE B CG1 1 ATOM 2790 C CG2 . ILE B 1 162 ? 53.949 20.327 16.183 1.00 28.77 ? 377 ILE B CG2 1 ATOM 2791 C CD1 . ILE B 1 162 ? 55.791 20.663 13.781 1.00 39.26 ? 377 ILE B CD1 1 ATOM 2792 N N . ALA B 1 163 ? 51.743 18.773 13.650 1.00 32.57 ? 378 ALA B N 1 ATOM 2793 C CA . ALA B 1 163 ? 51.336 17.381 13.632 1.00 34.39 ? 378 ALA B CA 1 ATOM 2794 C C . ALA B 1 163 ? 52.489 16.596 13.050 1.00 36.84 ? 378 ALA B C 1 ATOM 2795 O O . ALA B 1 163 ? 53.121 17.030 12.083 1.00 41.09 ? 378 ALA B O 1 ATOM 2796 C CB . ALA B 1 163 ? 50.105 17.204 12.796 1.00 35.78 ? 378 ALA B CB 1 ATOM 2797 N N . VAL B 1 164 ? 52.776 15.446 13.637 1.00 35.00 ? 379 VAL B N 1 ATOM 2798 C CA . VAL B 1 164 ? 53.891 14.655 13.173 1.00 36.32 ? 379 VAL B CA 1 ATOM 2799 C C . VAL B 1 164 ? 53.498 13.217 13.259 1.00 37.75 ? 379 VAL B C 1 ATOM 2800 O O . VAL B 1 164 ? 52.965 12.793 14.274 1.00 40.82 ? 379 VAL B O 1 ATOM 2801 C CB . VAL B 1 164 ? 55.127 14.848 14.080 1.00 36.24 ? 379 VAL B CB 1 ATOM 2802 C CG1 . VAL B 1 164 ? 56.329 14.121 13.494 1.00 35.51 ? 379 VAL B CG1 1 ATOM 2803 C CG2 . VAL B 1 164 ? 55.422 16.328 14.254 1.00 36.25 ? 379 VAL B CG2 1 ATOM 2804 N N . GLU B 1 165 ? 53.736 12.462 12.200 1.00 36.95 ? 380 GLU B N 1 ATOM 2805 C CA . GLU B 1 165 ? 53.425 11.057 12.254 1.00 39.12 ? 380 GLU B CA 1 ATOM 2806 C C . GLU B 1 165 ? 54.394 10.293 11.401 1.00 39.68 ? 380 GLU B C 1 ATOM 2807 O O . GLU B 1 165 ? 54.988 10.850 10.485 1.00 41.13 ? 380 GLU B O 1 ATOM 2808 C CB . GLU B 1 165 ? 51.973 10.772 11.858 1.00 41.71 ? 380 GLU B CB 1 ATOM 2809 C CG . GLU B 1 165 ? 51.484 11.318 10.535 1.00 49.05 ? 380 GLU B CG 1 ATOM 2810 C CD . GLU B 1 165 ? 50.037 10.892 10.243 1.00 52.48 ? 380 GLU B CD 1 ATOM 2811 O OE1 . GLU B 1 165 ? 49.832 9.825 9.608 1.00 54.29 ? 380 GLU B OE1 1 ATOM 2812 O OE2 . GLU B 1 165 ? 49.107 11.618 10.670 1.00 52.13 ? 380 GLU B OE2 1 ATOM 2813 N N . TRP B 1 166 ? 54.580 9.025 11.740 1.00 39.66 ? 381 TRP B N 1 ATOM 2814 C CA . TRP B 1 166 ? 55.502 8.164 11.025 1.00 42.16 ? 381 TRP B CA 1 ATOM 2815 C C . TRP B 1 166 ? 54.840 7.217 10.057 1.00 44.13 ? 381 TRP B C 1 ATOM 2816 O O . TRP B 1 166 ? 53.643 6.995 10.117 1.00 47.18 ? 381 TRP B O 1 ATOM 2817 C CB . TRP B 1 166 ? 56.298 7.331 12.012 1.00 41.98 ? 381 TRP B CB 1 ATOM 2818 C CG . TRP B 1 166 ? 57.289 8.109 12.753 1.00 39.47 ? 381 TRP B CG 1 ATOM 2819 C CD1 . TRP B 1 166 ? 57.070 8.877 13.845 1.00 38.15 ? 381 TRP B CD1 1 ATOM 2820 C CD2 . TRP B 1 166 ? 58.675 8.217 12.448 1.00 36.23 ? 381 TRP B CD2 1 ATOM 2821 N NE1 . TRP B 1 166 ? 58.243 9.458 14.247 1.00 39.30 ? 381 TRP B NE1 1 ATOM 2822 C CE2 . TRP B 1 166 ? 59.246 9.062 13.401 1.00 36.13 ? 381 TRP B CE2 1 ATOM 2823 C CE3 . TRP B 1 166 ? 59.489 7.678 11.454 1.00 37.05 ? 381 TRP B CE3 1 ATOM 2824 C CZ2 . TRP B 1 166 ? 60.589 9.386 13.399 1.00 35.03 ? 381 TRP B CZ2 1 ATOM 2825 C CZ3 . TRP B 1 166 ? 60.827 8.005 11.445 1.00 37.00 ? 381 TRP B CZ3 1 ATOM 2826 C CH2 . TRP B 1 166 ? 61.363 8.850 12.414 1.00 36.11 ? 381 TRP B CH2 1 ATOM 2827 N N . GLU B 1 167 ? 55.622 6.656 9.150 1.00 45.79 ? 382 GLU B N 1 ATOM 2828 C CA . GLU B 1 167 ? 55.056 5.694 8.232 1.00 48.87 ? 382 GLU B CA 1 ATOM 2829 C C . GLU B 1 167 ? 56.096 5.043 7.348 1.00 51.00 ? 382 GLU B C 1 ATOM 2830 O O . GLU B 1 167 ? 57.221 5.532 7.222 1.00 51.00 ? 382 GLU B O 1 ATOM 2831 C CB . GLU B 1 167 ? 53.969 6.336 7.385 1.00 48.23 ? 382 GLU B CB 1 ATOM 2832 C CG . GLU B 1 167 ? 54.462 7.011 6.150 1.00 52.02 ? 382 GLU B CG 1 ATOM 2833 C CD . GLU B 1 167 ? 53.740 8.311 5.901 1.00 55.29 ? 382 GLU B CD 1 ATOM 2834 O OE1 . GLU B 1 167 ? 53.591 8.681 4.711 1.00 55.62 ? 382 GLU B OE1 1 ATOM 2835 O OE2 . GLU B 1 167 ? 53.336 8.963 6.899 1.00 55.60 ? 382 GLU B OE2 1 ATOM 2836 N N . SER B 1 168 ? 55.699 3.912 6.770 1.00 52.80 ? 383 SER B N 1 ATOM 2837 C CA . SER B 1 168 ? 56.523 3.131 5.867 1.00 54.95 ? 383 SER B CA 1 ATOM 2838 C C . SER B 1 168 ? 55.564 2.449 4.909 1.00 57.30 ? 383 SER B C 1 ATOM 2839 O O . SER B 1 168 ? 54.437 2.136 5.283 1.00 56.78 ? 383 SER B O 1 ATOM 2840 C CB . SER B 1 168 ? 57.308 2.083 6.648 1.00 56.34 ? 383 SER B CB 1 ATOM 2841 O OG . SER B 1 168 ? 57.953 1.165 5.783 1.00 56.78 ? 383 SER B OG 1 ATOM 2842 N N . ASN B 1 169 ? 56.009 2.241 3.673 1.00 60.94 ? 384 ASN B N 1 ATOM 2843 C CA . ASN B 1 169 ? 55.209 1.580 2.636 1.00 63.24 ? 384 ASN B CA 1 ATOM 2844 C C . ASN B 1 169 ? 53.755 2.038 2.576 1.00 64.79 ? 384 ASN B C 1 ATOM 2845 O O . ASN B 1 169 ? 52.824 1.235 2.698 1.00 65.20 ? 384 ASN B O 1 ATOM 2846 C CB . ASN B 1 169 ? 55.276 0.072 2.837 1.00 63.79 ? 384 ASN B CB 1 ATOM 2847 C CG . ASN B 1 169 ? 56.704 -0.424 2.930 1.00 67.59 ? 384 ASN B CG 1 ATOM 2848 O OD1 . ASN B 1 169 ? 57.487 -0.262 1.991 1.00 68.95 ? 384 ASN B OD1 1 ATOM 2849 N ND2 . ASN B 1 169 ? 57.061 -1.015 4.071 1.00 68.54 ? 384 ASN B ND2 1 ATOM 2850 N N . GLY B 1 170 ? 53.578 3.341 2.374 1.00 65.59 ? 385 GLY B N 1 ATOM 2851 C CA . GLY B 1 170 ? 52.255 3.926 2.290 1.00 66.05 ? 385 GLY B CA 1 ATOM 2852 C C . GLY B 1 170 ? 51.522 3.910 3.614 1.00 66.35 ? 385 GLY B C 1 ATOM 2853 O O . GLY B 1 170 ? 51.101 4.953 4.128 1.00 66.70 ? 385 GLY B O 1 ATOM 2854 N N . GLN B 1 171 ? 51.373 2.715 4.168 1.00 65.65 ? 386 GLN B N 1 ATOM 2855 C CA . GLN B 1 171 ? 50.677 2.542 5.431 1.00 65.00 ? 386 GLN B CA 1 ATOM 2856 C C . GLN B 1 171 ? 51.373 3.233 6.581 1.00 61.88 ? 386 GLN B C 1 ATOM 2857 O O . GLN B 1 171 ? 52.598 3.289 6.629 1.00 62.74 ? 386 GLN B O 1 ATOM 2858 C CB . GLN B 1 171 ? 50.552 1.061 5.765 1.00 66.63 ? 386 GLN B CB 1 ATOM 2859 C CG . GLN B 1 171 ? 49.985 0.231 4.655 1.00 68.73 ? 386 GLN B CG 1 ATOM 2860 C CD . GLN B 1 171 ? 49.473 -1.075 5.176 1.00 70.30 ? 386 GLN B CD 1 ATOM 2861 O OE1 . GLN B 1 171 ? 50.166 -1.768 5.922 1.00 71.94 ? 386 GLN B OE1 1 ATOM 2862 N NE2 . GLN B 1 171 ? 48.249 -1.426 4.795 1.00 71.33 ? 386 GLN B NE2 1 ATOM 2863 N N . PRO B 1 172 ? 50.593 3.773 7.525 1.00 59.27 ? 387 PRO B N 1 ATOM 2864 C CA . PRO B 1 172 ? 51.142 4.463 8.693 1.00 58.48 ? 387 PRO B CA 1 ATOM 2865 C C . PRO B 1 172 ? 51.573 3.516 9.807 1.00 57.30 ? 387 PRO B C 1 ATOM 2866 O O . PRO B 1 172 ? 50.923 2.507 10.062 1.00 57.90 ? 387 PRO B O 1 ATOM 2867 C CB . PRO B 1 172 ? 49.999 5.379 9.120 1.00 58.86 ? 387 PRO B CB 1 ATOM 2868 C CG . PRO B 1 172 ? 48.793 4.607 8.720 1.00 58.61 ? 387 PRO B CG 1 ATOM 2869 C CD . PRO B 1 172 ? 49.164 4.080 7.361 1.00 58.20 ? 387 PRO B CD 1 ATOM 2870 N N . GLU B 1 173 ? 52.689 3.850 10.451 1.00 56.16 ? 388 GLU B N 1 ATOM 2871 C CA . GLU B 1 173 ? 53.234 3.073 11.555 1.00 52.79 ? 388 GLU B CA 1 ATOM 2872 C C . GLU B 1 173 ? 52.425 3.427 12.780 1.00 52.19 ? 388 GLU B C 1 ATOM 2873 O O . GLU B 1 173 ? 51.770 4.458 12.804 1.00 51.51 ? 388 GLU B O 1 ATOM 2874 C CB . GLU B 1 173 ? 54.697 3.435 11.760 1.00 50.99 ? 388 GLU B CB 1 ATOM 2875 C CG . GLU B 1 173 ? 55.613 2.768 10.759 1.00 52.06 ? 388 GLU B CG 1 ATOM 2876 C CD . GLU B 1 173 ? 55.824 1.303 11.076 1.00 54.06 ? 388 GLU B CD 1 ATOM 2877 O OE1 . GLU B 1 173 ? 56.470 0.600 10.276 1.00 51.78 ? 388 GLU B OE1 1 ATOM 2878 O OE2 . GLU B 1 173 ? 55.342 0.855 12.141 1.00 59.16 ? 388 GLU B OE2 1 ATOM 2879 N N . ASN B 1 174 ? 52.460 2.591 13.805 1.00 52.81 ? 389 ASN B N 1 ATOM 2880 C CA . ASN B 1 174 ? 51.660 2.894 14.989 1.00 53.99 ? 389 ASN B CA 1 ATOM 2881 C C . ASN B 1 174 ? 52.489 3.089 16.257 1.00 52.17 ? 389 ASN B C 1 ATOM 2882 O O . ASN B 1 174 ? 52.237 3.996 17.061 1.00 52.92 ? 389 ASN B O 1 ATOM 2883 C CB . ASN B 1 174 ? 50.616 1.781 15.234 1.00 57.77 ? 389 ASN B CB 1 ATOM 2884 C CG . ASN B 1 174 ? 50.549 0.752 14.094 1.00 60.90 ? 389 ASN B CG 1 ATOM 2885 O OD1 . ASN B 1 174 ? 51.544 0.072 13.782 1.00 62.79 ? 389 ASN B OD1 1 ATOM 2886 N ND2 . ASN B 1 174 ? 49.369 0.632 13.474 1.00 57.37 ? 389 ASN B ND2 1 ATOM 2887 N N . ASN B 1 175 ? 53.481 2.233 16.434 1.00 48.49 ? 390 ASN B N 1 ATOM 2888 C CA . ASN B 1 175 ? 54.306 2.298 17.619 1.00 44.84 ? 390 ASN B CA 1 ATOM 2889 C C . ASN B 1 175 ? 55.314 3.438 17.606 1.00 42.30 ? 390 ASN B C 1 ATOM 2890 O O . ASN B 1 175 ? 56.513 3.227 17.464 1.00 41.91 ? 390 ASN B O 1 ATOM 2891 C CB . ASN B 1 175 ? 55.008 0.961 17.818 1.00 43.57 ? 390 ASN B CB 1 ATOM 2892 C CG . ASN B 1 175 ? 55.702 0.879 19.131 1.00 45.37 ? 390 ASN B CG 1 ATOM 2893 O OD1 . ASN B 1 175 ? 55.142 1.232 20.169 1.00 44.96 ? 390 ASN B OD1 1 ATOM 2894 N ND2 . ASN B 1 175 ? 56.937 0.409 19.108 1.00 49.03 ? 390 ASN B ND2 1 ATOM 2895 N N . TYR B 1 176 ? 54.813 4.653 17.759 1.00 39.46 ? 391 TYR B N 1 ATOM 2896 C CA . TYR B 1 176 ? 55.670 5.817 17.794 1.00 38.61 ? 391 TYR B CA 1 ATOM 2897 C C . TYR B 1 176 ? 55.110 6.835 18.790 1.00 38.34 ? 391 TYR B C 1 ATOM 2898 O O . TYR B 1 176 ? 53.908 6.875 19.038 1.00 38.52 ? 391 TYR B O 1 ATOM 2899 C CB . TYR B 1 176 ? 55.775 6.419 16.396 1.00 38.39 ? 391 TYR B CB 1 ATOM 2900 C CG . TYR B 1 176 ? 54.572 7.212 15.952 1.00 39.80 ? 391 TYR B CG 1 ATOM 2901 C CD1 . TYR B 1 176 ? 54.314 8.471 16.488 1.00 40.70 ? 391 TYR B CD1 1 ATOM 2902 C CD2 . TYR B 1 176 ? 53.707 6.727 14.969 1.00 39.94 ? 391 TYR B CD2 1 ATOM 2903 C CE1 . TYR B 1 176 ? 53.229 9.233 16.059 1.00 41.53 ? 391 TYR B CE1 1 ATOM 2904 C CE2 . TYR B 1 176 ? 52.616 7.483 14.531 1.00 38.59 ? 391 TYR B CE2 1 ATOM 2905 C CZ . TYR B 1 176 ? 52.386 8.733 15.087 1.00 40.42 ? 391 TYR B CZ 1 ATOM 2906 O OH . TYR B 1 176 ? 51.303 9.493 14.710 1.00 43.32 ? 391 TYR B OH 1 ATOM 2907 N N . LYS B 1 177 ? 55.984 7.647 19.373 1.00 37.54 ? 392 LYS B N 1 ATOM 2908 C CA . LYS B 1 177 ? 55.568 8.658 20.338 1.00 35.34 ? 392 LYS B CA 1 ATOM 2909 C C . LYS B 1 177 ? 56.175 10.027 20.047 1.00 34.11 ? 392 LYS B C 1 ATOM 2910 O O . LYS B 1 177 ? 57.323 10.146 19.628 1.00 34.73 ? 392 LYS B O 1 ATOM 2911 C CB . LYS B 1 177 ? 55.949 8.215 21.745 1.00 35.84 ? 392 LYS B CB 1 ATOM 2912 C CG . LYS B 1 177 ? 55.110 7.068 22.281 1.00 37.55 ? 392 LYS B CG 1 ATOM 2913 C CD . LYS B 1 177 ? 53.707 7.547 22.627 1.00 39.70 ? 392 LYS B CD 1 ATOM 2914 C CE . LYS B 1 177 ? 52.813 6.434 23.165 1.00 40.29 ? 392 LYS B CE 1 ATOM 2915 N NZ . LYS B 1 177 ? 51.483 6.998 23.567 1.00 40.85 ? 392 LYS B NZ 1 ATOM 2916 N N . THR B 1 178 ? 55.394 11.070 20.261 1.00 32.92 ? 393 THR B N 1 ATOM 2917 C CA . THR B 1 178 ? 55.888 12.409 20.010 1.00 31.82 ? 393 THR B CA 1 ATOM 2918 C C . THR B 1 178 ? 55.829 13.244 21.268 1.00 31.89 ? 393 THR B C 1 ATOM 2919 O O . THR B 1 178 ? 54.818 13.262 21.958 1.00 34.48 ? 393 THR B O 1 ATOM 2920 C CB . THR B 1 178 ? 55.076 13.094 18.945 1.00 29.50 ? 393 THR B CB 1 ATOM 2921 O OG1 . THR B 1 178 ? 55.020 12.256 17.793 1.00 28.98 ? 393 THR B OG1 1 ATOM 2922 C CG2 . THR B 1 178 ? 55.711 14.412 18.578 1.00 30.84 ? 393 THR B CG2 1 ATOM 2923 N N . THR B 1 179 ? 56.922 13.932 21.568 1.00 31.73 ? 394 THR B N 1 ATOM 2924 C CA . THR B 1 179 ? 56.981 14.768 22.750 1.00 31.34 ? 394 THR B CA 1 ATOM 2925 C C . THR B 1 179 ? 56.175 16.041 22.490 1.00 33.47 ? 394 THR B C 1 ATOM 2926 O O . THR B 1 179 ? 55.800 16.346 21.351 1.00 33.37 ? 394 THR B O 1 ATOM 2927 C CB . THR B 1 179 ? 58.410 15.197 23.047 1.00 30.21 ? 394 THR B CB 1 ATOM 2928 O OG1 . THR B 1 179 ? 58.701 16.396 22.315 1.00 28.59 ? 394 THR B OG1 1 ATOM 2929 C CG2 . THR B 1 179 ? 59.381 14.117 22.634 1.00 26.38 ? 394 THR B CG2 1 ATOM 2930 N N . PRO B 1 180 ? 55.866 16.783 23.556 1.00 33.48 ? 395 PRO B N 1 ATOM 2931 C CA . PRO B 1 180 ? 55.113 18.030 23.446 1.00 34.95 ? 395 PRO B CA 1 ATOM 2932 C C . PRO B 1 180 ? 56.047 19.065 22.840 1.00 36.49 ? 395 PRO B C 1 ATOM 2933 O O . PRO B 1 180 ? 57.265 18.883 22.870 1.00 39.17 ? 395 PRO B O 1 ATOM 2934 C CB . PRO B 1 180 ? 54.772 18.338 24.887 1.00 33.96 ? 395 PRO B CB 1 ATOM 2935 C CG . PRO B 1 180 ? 54.599 16.984 25.454 1.00 33.12 ? 395 PRO B CG 1 ATOM 2936 C CD . PRO B 1 180 ? 55.781 16.256 24.923 1.00 32.53 ? 395 PRO B CD 1 ATOM 2937 N N . PRO B 1 181 ? 55.501 20.150 22.265 1.00 36.04 ? 396 PRO B N 1 ATOM 2938 C CA . PRO B 1 181 ? 56.401 21.144 21.679 1.00 35.12 ? 396 PRO B CA 1 ATOM 2939 C C . PRO B 1 181 ? 57.151 21.754 22.824 1.00 35.42 ? 396 PRO B C 1 ATOM 2940 O O . PRO B 1 181 ? 56.570 21.984 23.883 1.00 37.36 ? 396 PRO B O 1 ATOM 2941 C CB . PRO B 1 181 ? 55.450 22.135 21.038 1.00 35.11 ? 396 PRO B CB 1 ATOM 2942 C CG . PRO B 1 181 ? 54.229 21.311 20.764 1.00 36.00 ? 396 PRO B CG 1 ATOM 2943 C CD . PRO B 1 181 ? 54.100 20.517 22.022 1.00 34.65 ? 396 PRO B CD 1 ATOM 2944 N N . VAL B 1 182 ? 58.438 21.996 22.637 1.00 34.54 ? 397 VAL B N 1 ATOM 2945 C CA . VAL B 1 182 ? 59.225 22.585 23.710 1.00 34.77 ? 397 VAL B CA 1 ATOM 2946 C C . VAL B 1 182 ? 59.734 23.977 23.326 1.00 36.19 ? 397 VAL B C 1 ATOM 2947 O O . VAL B 1 182 ? 60.254 24.172 22.223 1.00 37.65 ? 397 VAL B O 1 ATOM 2948 C CB . VAL B 1 182 ? 60.410 21.681 24.076 1.00 32.20 ? 397 VAL B CB 1 ATOM 2949 C CG1 . VAL B 1 182 ? 61.222 22.319 25.173 1.00 32.09 ? 397 VAL B CG1 1 ATOM 2950 C CG2 . VAL B 1 182 ? 59.909 20.330 24.514 1.00 26.53 ? 397 VAL B CG2 1 ATOM 2951 N N . LEU B 1 183 ? 59.569 24.944 24.228 1.00 36.16 ? 398 LEU B N 1 ATOM 2952 C CA . LEU B 1 183 ? 60.016 26.299 23.954 1.00 36.74 ? 398 LEU B CA 1 ATOM 2953 C C . LEU B 1 183 ? 61.506 26.329 23.974 1.00 36.94 ? 398 LEU B C 1 ATOM 2954 O O . LEU B 1 183 ? 62.112 26.113 25.005 1.00 37.24 ? 398 LEU B O 1 ATOM 2955 C CB . LEU B 1 183 ? 59.501 27.283 24.990 1.00 38.57 ? 398 LEU B CB 1 ATOM 2956 C CG . LEU B 1 183 ? 60.002 28.711 24.713 1.00 40.04 ? 398 LEU B CG 1 ATOM 2957 C CD1 . LEU B 1 183 ? 59.714 29.113 23.263 1.00 38.00 ? 398 LEU B CD1 1 ATOM 2958 C CD2 . LEU B 1 183 ? 59.335 29.676 25.695 1.00 39.83 ? 398 LEU B CD2 1 ATOM 2959 N N . ASP B 1 184 ? 62.101 26.608 22.831 1.00 39.51 ? 399 ASP B N 1 ATOM 2960 C CA . ASP B 1 184 ? 63.540 26.631 22.751 1.00 42.44 ? 399 ASP B CA 1 ATOM 2961 C C . ASP B 1 184 ? 64.085 27.931 23.294 1.00 44.41 ? 399 ASP B C 1 ATOM 2962 O O . ASP B 1 184 ? 63.333 28.757 23.813 1.00 44.18 ? 399 ASP B O 1 ATOM 2963 C CB . ASP B 1 184 ? 63.985 26.450 21.315 1.00 45.07 ? 399 ASP B CB 1 ATOM 2964 C CG . ASP B 1 184 ? 65.269 25.689 21.216 1.00 47.15 ? 399 ASP B CG 1 ATOM 2965 O OD1 . ASP B 1 184 ? 66.222 26.056 21.940 1.00 47.38 ? 399 ASP B OD1 1 ATOM 2966 O OD2 . ASP B 1 184 ? 65.319 24.725 20.419 1.00 48.11 ? 399 ASP B OD2 1 ATOM 2967 N N . SER B 1 185 ? 65.395 28.116 23.169 1.00 45.03 ? 400 SER B N 1 ATOM 2968 C CA . SER B 1 185 ? 66.019 29.324 23.678 1.00 46.12 ? 400 SER B CA 1 ATOM 2969 C C . SER B 1 185 ? 65.827 30.521 22.759 1.00 46.36 ? 400 SER B C 1 ATOM 2970 O O . SER B 1 185 ? 65.619 31.629 23.237 1.00 47.80 ? 400 SER B O 1 ATOM 2971 C CB . SER B 1 185 ? 67.511 29.099 23.909 1.00 45.47 ? 400 SER B CB 1 ATOM 2972 O OG . SER B 1 185 ? 68.228 29.167 22.691 1.00 46.35 ? 400 SER B OG 1 ATOM 2973 N N . ASP B 1 186 ? 65.880 30.294 21.448 1.00 46.59 ? 401 ASP B N 1 ATOM 2974 C CA . ASP B 1 186 ? 65.744 31.378 20.470 1.00 45.50 ? 401 ASP B CA 1 ATOM 2975 C C . ASP B 1 186 ? 64.315 31.817 20.196 1.00 43.72 ? 401 ASP B C 1 ATOM 2976 O O . ASP B 1 186 ? 64.087 32.569 19.261 1.00 44.19 ? 401 ASP B O 1 ATOM 2977 C CB . ASP B 1 186 ? 66.389 30.981 19.138 1.00 48.40 ? 401 ASP B CB 1 ATOM 2978 C CG . ASP B 1 186 ? 65.469 30.131 18.270 1.00 53.22 ? 401 ASP B CG 1 ATOM 2979 O OD1 . ASP B 1 186 ? 64.612 29.401 18.821 1.00 56.27 ? 401 ASP B OD1 1 ATOM 2980 O OD2 . ASP B 1 186 ? 65.609 30.180 17.030 1.00 54.62 ? 401 ASP B OD2 1 ATOM 2981 N N . GLY B 1 187 ? 63.357 31.337 20.986 1.00 42.13 ? 402 GLY B N 1 ATOM 2982 C CA . GLY B 1 187 ? 61.972 31.737 20.789 1.00 39.67 ? 402 GLY B CA 1 ATOM 2983 C C . GLY B 1 187 ? 61.083 30.788 20.002 1.00 38.16 ? 402 GLY B C 1 ATOM 2984 O O . GLY B 1 187 ? 59.855 30.932 19.999 1.00 35.30 ? 402 GLY B O 1 ATOM 2985 N N . SER B 1 188 ? 61.691 29.827 19.317 1.00 37.80 ? 403 SER B N 1 ATOM 2986 C CA . SER B 1 188 ? 60.917 28.846 18.557 1.00 37.81 ? 403 SER B CA 1 ATOM 2987 C C . SER B 1 188 ? 60.684 27.586 19.391 1.00 37.17 ? 403 SER B C 1 ATOM 2988 O O . SER B 1 188 ? 61.163 27.459 20.519 1.00 38.02 ? 403 SER B O 1 ATOM 2989 C CB . SER B 1 188 ? 61.648 28.462 17.268 1.00 37.65 ? 403 SER B CB 1 ATOM 2990 O OG . SER B 1 188 ? 62.939 27.953 17.559 1.00 38.48 ? 403 SER B OG 1 ATOM 2991 N N . PHE B 1 189 ? 59.931 26.653 18.834 1.00 35.38 ? 404 PHE B N 1 ATOM 2992 C CA . PHE B 1 189 ? 59.674 25.411 19.525 1.00 33.28 ? 404 PHE B CA 1 ATOM 2993 C C . PHE B 1 189 ? 60.378 24.280 18.780 1.00 33.59 ? 404 PHE B C 1 ATOM 2994 O O . PHE B 1 189 ? 60.803 24.449 17.624 1.00 33.60 ? 404 PHE B O 1 ATOM 2995 C CB . PHE B 1 189 ? 58.178 25.127 19.564 1.00 32.04 ? 404 PHE B CB 1 ATOM 2996 C CG . PHE B 1 189 ? 57.393 26.110 20.369 1.00 32.02 ? 404 PHE B CG 1 ATOM 2997 C CD1 . PHE B 1 189 ? 56.860 27.245 19.778 1.00 32.95 ? 404 PHE B CD1 1 ATOM 2998 C CD2 . PHE B 1 189 ? 57.177 25.900 21.726 1.00 30.25 ? 404 PHE B CD2 1 ATOM 2999 C CE1 . PHE B 1 189 ? 56.122 28.152 20.537 1.00 32.49 ? 404 PHE B CE1 1 ATOM 3000 C CE2 . PHE B 1 189 ? 56.446 26.803 22.485 1.00 27.13 ? 404 PHE B CE2 1 ATOM 3001 C CZ . PHE B 1 189 ? 55.921 27.920 21.900 1.00 29.01 ? 404 PHE B CZ 1 ATOM 3002 N N . PHE B 1 190 ? 60.509 23.140 19.458 1.00 31.12 ? 405 PHE B N 1 ATOM 3003 C CA . PHE B 1 190 ? 61.105 21.940 18.883 1.00 29.43 ? 405 PHE B CA 1 ATOM 3004 C C . PHE B 1 190 ? 60.477 20.788 19.618 1.00 30.25 ? 405 PHE B C 1 ATOM 3005 O O . PHE B 1 190 ? 59.867 20.970 20.678 1.00 31.73 ? 405 PHE B O 1 ATOM 3006 C CB . PHE B 1 190 ? 62.623 21.894 19.089 1.00 30.60 ? 405 PHE B CB 1 ATOM 3007 C CG . PHE B 1 190 ? 63.045 21.448 20.463 1.00 31.16 ? 405 PHE B CG 1 ATOM 3008 C CD1 . PHE B 1 190 ? 63.391 20.126 20.702 1.00 30.37 ? 405 PHE B CD1 1 ATOM 3009 C CD2 . PHE B 1 190 ? 63.059 22.349 21.531 1.00 33.03 ? 405 PHE B CD2 1 ATOM 3010 C CE1 . PHE B 1 190 ? 63.741 19.702 21.977 1.00 28.69 ? 405 PHE B CE1 1 ATOM 3011 C CE2 . PHE B 1 190 ? 63.408 21.938 22.814 1.00 30.34 ? 405 PHE B CE2 1 ATOM 3012 C CZ . PHE B 1 190 ? 63.749 20.610 23.036 1.00 30.26 ? 405 PHE B CZ 1 ATOM 3013 N N . LEU B 1 191 ? 60.610 19.602 19.048 1.00 28.25 ? 406 LEU B N 1 ATOM 3014 C CA . LEU B 1 191 ? 60.084 18.409 19.669 1.00 28.19 ? 406 LEU B CA 1 ATOM 3015 C C . LEU B 1 191 ? 60.764 17.256 18.997 1.00 30.14 ? 406 LEU B C 1 ATOM 3016 O O . LEU B 1 191 ? 61.454 17.427 17.986 1.00 31.95 ? 406 LEU B O 1 ATOM 3017 C CB . LEU B 1 191 ? 58.570 18.302 19.489 1.00 27.48 ? 406 LEU B CB 1 ATOM 3018 C CG . LEU B 1 191 ? 57.960 18.355 18.080 1.00 29.33 ? 406 LEU B CG 1 ATOM 3019 C CD1 . LEU B 1 191 ? 58.418 17.189 17.221 1.00 29.73 ? 406 LEU B CD1 1 ATOM 3020 C CD2 . LEU B 1 191 ? 56.452 18.316 18.200 1.00 29.51 ? 406 LEU B CD2 1 ATOM 3021 N N . TYR B 1 192 ? 60.572 16.081 19.569 1.00 30.71 ? 407 TYR B N 1 ATOM 3022 C CA . TYR B 1 192 ? 61.144 14.863 19.035 1.00 31.69 ? 407 TYR B CA 1 ATOM 3023 C C . TYR B 1 192 ? 60.018 13.862 18.925 1.00 33.06 ? 407 TYR B C 1 ATOM 3024 O O . TYR B 1 192 ? 59.080 13.874 19.719 1.00 33.56 ? 407 TYR B O 1 ATOM 3025 C CB . TYR B 1 192 ? 62.197 14.307 19.981 1.00 30.95 ? 407 TYR B CB 1 ATOM 3026 C CG . TYR B 1 192 ? 63.519 15.011 19.940 1.00 31.44 ? 407 TYR B CG 1 ATOM 3027 C CD1 . TYR B 1 192 ? 64.576 14.485 19.210 1.00 32.87 ? 407 TYR B CD1 1 ATOM 3028 C CD2 . TYR B 1 192 ? 63.735 16.186 20.666 1.00 31.11 ? 407 TYR B CD2 1 ATOM 3029 C CE1 . TYR B 1 192 ? 65.822 15.103 19.207 1.00 31.82 ? 407 TYR B CE1 1 ATOM 3030 C CE2 . TYR B 1 192 ? 64.976 16.811 20.666 1.00 28.01 ? 407 TYR B CE2 1 ATOM 3031 C CZ . TYR B 1 192 ? 66.011 16.259 19.937 1.00 28.94 ? 407 TYR B CZ 1 ATOM 3032 O OH . TYR B 1 192 ? 67.254 16.825 19.953 1.00 28.97 ? 407 TYR B OH 1 ATOM 3033 N N . SER B 1 193 ? 60.124 12.992 17.937 1.00 33.30 ? 408 SER B N 1 ATOM 3034 C CA . SER B 1 193 ? 59.129 11.964 17.722 1.00 33.38 ? 408 SER B CA 1 ATOM 3035 C C . SER B 1 193 ? 59.938 10.672 17.613 1.00 34.50 ? 408 SER B C 1 ATOM 3036 O O . SER B 1 193 ? 60.856 10.554 16.784 1.00 35.14 ? 408 SER B O 1 ATOM 3037 C CB . SER B 1 193 ? 58.367 12.267 16.430 1.00 33.38 ? 408 SER B CB 1 ATOM 3038 O OG . SER B 1 193 ? 57.444 11.256 16.113 1.00 33.80 ? 408 SER B OG 1 ATOM 3039 N N . LYS B 1 194 ? 59.615 9.711 18.470 1.00 32.79 ? 409 LYS B N 1 ATOM 3040 C CA . LYS B 1 194 ? 60.322 8.437 18.483 1.00 30.99 ? 409 LYS B CA 1 ATOM 3041 C C . LYS B 1 194 ? 59.462 7.279 17.973 1.00 29.24 ? 409 LYS B C 1 ATOM 3042 O O . LYS B 1 194 ? 58.385 7.014 18.486 1.00 28.04 ? 409 LYS B O 1 ATOM 3043 C CB . LYS B 1 194 ? 60.813 8.147 19.904 1.00 30.04 ? 409 LYS B CB 1 ATOM 3044 C CG . LYS B 1 194 ? 61.544 6.831 20.079 1.00 30.01 ? 409 LYS B CG 1 ATOM 3045 C CD . LYS B 1 194 ? 62.018 6.660 21.522 1.00 30.10 ? 409 LYS B CD 1 ATOM 3046 C CE . LYS B 1 194 ? 60.845 6.545 22.502 1.00 30.38 ? 409 LYS B CE 1 ATOM 3047 N NZ . LYS B 1 194 ? 60.083 5.270 22.325 1.00 30.31 ? 409 LYS B NZ 1 ATOM 3048 N N . LEU B 1 195 ? 59.952 6.603 16.941 1.00 27.99 ? 410 LEU B N 1 ATOM 3049 C CA . LEU B 1 195 ? 59.263 5.462 16.361 1.00 26.32 ? 410 LEU B CA 1 ATOM 3050 C C . LEU B 1 195 ? 60.063 4.262 16.771 1.00 25.75 ? 410 LEU B C 1 ATOM 3051 O O . LEU B 1 195 ? 61.277 4.331 16.814 1.00 28.28 ? 410 LEU B O 1 ATOM 3052 C CB . LEU B 1 195 ? 59.244 5.537 14.832 1.00 27.02 ? 410 LEU B CB 1 ATOM 3053 C CG . LEU B 1 195 ? 58.908 4.223 14.109 1.00 25.93 ? 410 LEU B CG 1 ATOM 3054 C CD1 . LEU B 1 195 ? 57.502 3.786 14.463 1.00 24.27 ? 410 LEU B CD1 1 ATOM 3055 C CD2 . LEU B 1 195 ? 59.048 4.401 12.609 1.00 22.65 ? 410 LEU B CD2 1 ATOM 3056 N N . THR B 1 196 ? 59.387 3.163 17.071 1.00 25.12 ? 411 THR B N 1 ATOM 3057 C CA . THR B 1 196 ? 60.061 1.935 17.471 1.00 23.55 ? 411 THR B CA 1 ATOM 3058 C C . THR B 1 196 ? 59.784 0.872 16.442 1.00 22.86 ? 411 THR B C 1 ATOM 3059 O O . THR B 1 196 ? 58.634 0.594 16.135 1.00 24.85 ? 411 THR B O 1 ATOM 3060 C CB . THR B 1 196 ? 59.547 1.458 18.815 1.00 22.11 ? 411 THR B CB 1 ATOM 3061 O OG1 . THR B 1 196 ? 59.869 2.449 19.790 1.00 26.80 ? 411 THR B OG1 1 ATOM 3062 C CG2 . THR B 1 196 ? 60.164 0.130 19.202 1.00 18.96 ? 411 THR B CG2 1 ATOM 3063 N N . VAL B 1 197 ? 60.834 0.279 15.904 1.00 22.15 ? 412 VAL B N 1 ATOM 3064 C CA . VAL B 1 197 ? 60.664 -0.757 14.904 1.00 25.16 ? 412 VAL B CA 1 ATOM 3065 C C . VAL B 1 197 ? 61.532 -1.955 15.251 1.00 28.96 ? 412 VAL B C 1 ATOM 3066 O O . VAL B 1 197 ? 62.584 -1.802 15.846 1.00 31.42 ? 412 VAL B O 1 ATOM 3067 C CB . VAL B 1 197 ? 61.070 -0.244 13.513 1.00 24.14 ? 412 VAL B CB 1 ATOM 3068 C CG1 . VAL B 1 197 ? 60.491 1.146 13.291 1.00 24.74 ? 412 VAL B CG1 1 ATOM 3069 C CG2 . VAL B 1 197 ? 62.576 -0.239 13.375 1.00 19.65 ? 412 VAL B CG2 1 ATOM 3070 N N . ASP B 1 198 ? 61.090 -3.151 14.891 1.00 32.55 ? 413 ASP B N 1 ATOM 3071 C CA . ASP B 1 198 ? 61.872 -4.346 15.167 1.00 35.73 ? 413 ASP B CA 1 ATOM 3072 C C . ASP B 1 198 ? 63.213 -4.260 14.475 1.00 35.79 ? 413 ASP B C 1 ATOM 3073 O O . ASP B 1 198 ? 63.290 -3.930 13.297 1.00 36.13 ? 413 ASP B O 1 ATOM 3074 C CB . ASP B 1 198 ? 61.119 -5.568 14.689 1.00 40.18 ? 413 ASP B CB 1 ATOM 3075 C CG . ASP B 1 198 ? 59.798 -5.727 15.399 1.00 46.41 ? 413 ASP B CG 1 ATOM 3076 O OD1 . ASP B 1 198 ? 59.812 -6.070 16.610 1.00 46.80 ? 413 ASP B OD1 1 ATOM 3077 O OD2 . ASP B 1 198 ? 58.751 -5.491 14.750 1.00 49.02 ? 413 ASP B OD2 1 ATOM 3078 N N . LYS B 1 199 ? 64.269 -4.549 15.221 1.00 36.14 ? 414 LYS B N 1 ATOM 3079 C CA . LYS B 1 199 ? 65.631 -4.496 14.703 1.00 36.88 ? 414 LYS B CA 1 ATOM 3080 C C . LYS B 1 199 ? 65.767 -5.097 13.309 1.00 38.93 ? 414 LYS B C 1 ATOM 3081 O O . LYS B 1 199 ? 66.492 -4.571 12.466 1.00 38.46 ? 414 LYS B O 1 ATOM 3082 C CB . LYS B 1 199 ? 66.551 -5.209 15.689 1.00 35.95 ? 414 LYS B CB 1 ATOM 3083 C CG . LYS B 1 199 ? 67.914 -5.624 15.186 1.00 33.06 ? 414 LYS B CG 1 ATOM 3084 C CD . LYS B 1 199 ? 68.634 -6.306 16.348 1.00 37.21 ? 414 LYS B CD 1 ATOM 3085 C CE . LYS B 1 199 ? 69.814 -7.122 15.903 1.00 36.76 ? 414 LYS B CE 1 ATOM 3086 N NZ . LYS B 1 199 ? 70.749 -6.268 15.136 1.00 45.13 ? 414 LYS B NZ 1 ATOM 3087 N N . SER B 1 200 ? 65.049 -6.192 13.066 1.00 41.53 ? 415 SER B N 1 ATOM 3088 C CA . SER B 1 200 ? 65.096 -6.878 11.779 1.00 42.04 ? 415 SER B CA 1 ATOM 3089 C C . SER B 1 200 ? 64.564 -6.013 10.646 1.00 41.32 ? 415 SER B C 1 ATOM 3090 O O . SER B 1 200 ? 65.106 -6.023 9.546 1.00 42.13 ? 415 SER B O 1 ATOM 3091 C CB . SER B 1 200 ? 64.310 -8.184 11.852 1.00 43.30 ? 415 SER B CB 1 ATOM 3092 O OG . SER B 1 200 ? 62.945 -7.938 12.129 1.00 47.17 ? 415 SER B OG 1 ATOM 3093 N N . ARG B 1 201 ? 63.505 -5.261 10.899 1.00 41.26 ? 416 ARG B N 1 ATOM 3094 C CA . ARG B 1 201 ? 62.972 -4.408 9.850 1.00 41.49 ? 416 ARG B CA 1 ATOM 3095 C C . ARG B 1 201 ? 63.964 -3.309 9.535 1.00 41.60 ? 416 ARG B C 1 ATOM 3096 O O . ARG B 1 201 ? 64.073 -2.887 8.392 1.00 43.03 ? 416 ARG B O 1 ATOM 3097 C CB . ARG B 1 201 ? 61.647 -3.785 10.266 1.00 41.53 ? 416 ARG B CB 1 ATOM 3098 C CG . ARG B 1 201 ? 60.554 -4.783 10.509 1.00 46.04 ? 416 ARG B CG 1 ATOM 3099 C CD . ARG B 1 201 ? 59.254 -4.068 10.724 1.00 50.92 ? 416 ARG B CD 1 ATOM 3100 N NE . ARG B 1 201 ? 59.025 -3.113 9.649 1.00 53.76 ? 416 ARG B NE 1 ATOM 3101 C CZ . ARG B 1 201 ? 58.058 -2.204 9.653 1.00 56.01 ? 416 ARG B CZ 1 ATOM 3102 N NH1 . ARG B 1 201 ? 57.225 -2.127 10.681 1.00 55.80 ? 416 ARG B NH1 1 ATOM 3103 N NH2 . ARG B 1 201 ? 57.932 -1.365 8.629 1.00 58.40 ? 416 ARG B NH2 1 ATOM 3104 N N . TRP B 1 202 ? 64.690 -2.841 10.544 1.00 40.41 ? 417 TRP B N 1 ATOM 3105 C CA . TRP B 1 202 ? 65.662 -1.788 10.315 1.00 41.04 ? 417 TRP B CA 1 ATOM 3106 C C . TRP B 1 202 ? 66.897 -2.328 9.598 1.00 42.62 ? 417 TRP B C 1 ATOM 3107 O O . TRP B 1 202 ? 67.310 -1.798 8.566 1.00 41.89 ? 417 TRP B O 1 ATOM 3108 C CB . TRP B 1 202 ? 66.053 -1.134 11.633 1.00 38.79 ? 417 TRP B CB 1 ATOM 3109 C CG . TRP B 1 202 ? 67.121 -0.117 11.494 1.00 38.63 ? 417 TRP B CG 1 ATOM 3110 C CD1 . TRP B 1 202 ? 68.418 -0.230 11.901 1.00 39.96 ? 417 TRP B CD1 1 ATOM 3111 C CD2 . TRP B 1 202 ? 66.999 1.177 10.905 1.00 39.28 ? 417 TRP B CD2 1 ATOM 3112 N NE1 . TRP B 1 202 ? 69.115 0.916 11.604 1.00 39.20 ? 417 TRP B NE1 1 ATOM 3113 C CE2 . TRP B 1 202 ? 68.266 1.798 10.989 1.00 38.83 ? 417 TRP B CE2 1 ATOM 3114 C CE3 . TRP B 1 202 ? 65.943 1.878 10.312 1.00 39.55 ? 417 TRP B CE3 1 ATOM 3115 C CZ2 . TRP B 1 202 ? 68.504 3.083 10.503 1.00 36.65 ? 417 TRP B CZ2 1 ATOM 3116 C CZ3 . TRP B 1 202 ? 66.185 3.160 9.828 1.00 38.71 ? 417 TRP B CZ3 1 ATOM 3117 C CH2 . TRP B 1 202 ? 67.457 3.745 9.928 1.00 37.49 ? 417 TRP B CH2 1 ATOM 3118 N N . GLN B 1 203 ? 67.478 -3.391 10.141 1.00 44.49 ? 418 GLN B N 1 ATOM 3119 C CA . GLN B 1 203 ? 68.662 -4.010 9.546 1.00 46.33 ? 418 GLN B CA 1 ATOM 3120 C C . GLN B 1 203 ? 68.460 -4.346 8.064 1.00 46.82 ? 418 GLN B C 1 ATOM 3121 O O . GLN B 1 203 ? 69.387 -4.241 7.258 1.00 46.90 ? 418 GLN B O 1 ATOM 3122 C CB . GLN B 1 203 ? 69.019 -5.286 10.314 1.00 46.85 ? 418 GLN B CB 1 ATOM 3123 C CG . GLN B 1 203 ? 69.570 -5.055 11.715 1.00 48.79 ? 418 GLN B CG 1 ATOM 3124 C CD . GLN B 1 203 ? 70.948 -4.415 11.707 1.00 50.80 ? 418 GLN B CD 1 ATOM 3125 O OE1 . GLN B 1 203 ? 71.112 -3.257 11.323 1.00 52.24 ? 418 GLN B OE1 1 ATOM 3126 N NE2 . GLN B 1 203 ? 71.947 -5.172 12.126 1.00 52.65 ? 418 GLN B NE2 1 ATOM 3127 N N . GLN B 1 204 ? 67.237 -4.743 7.722 1.00 47.60 ? 419 GLN B N 1 ATOM 3128 C CA . GLN B 1 204 ? 66.868 -5.110 6.360 1.00 46.94 ? 419 GLN B CA 1 ATOM 3129 C C . GLN B 1 204 ? 66.885 -3.939 5.406 1.00 45.24 ? 419 GLN B C 1 ATOM 3130 O O . GLN B 1 204 ? 66.914 -4.131 4.204 1.00 46.37 ? 419 GLN B O 1 ATOM 3131 C CB . GLN B 1 204 ? 65.473 -5.714 6.335 1.00 49.21 ? 419 GLN B CB 1 ATOM 3132 C CG . GLN B 1 204 ? 65.407 -7.184 6.622 1.00 55.45 ? 419 GLN B CG 1 ATOM 3133 C CD . GLN B 1 204 ? 63.992 -7.616 6.968 1.00 62.04 ? 419 GLN B CD 1 ATOM 3134 O OE1 . GLN B 1 204 ? 63.007 -7.147 6.359 1.00 61.29 ? 419 GLN B OE1 1 ATOM 3135 N NE2 . GLN B 1 204 ? 63.875 -8.518 7.950 1.00 64.52 ? 419 GLN B NE2 1 ATOM 3136 N N . GLY B 1 205 ? 66.833 -2.726 5.931 1.00 43.43 ? 420 GLY B N 1 ATOM 3137 C CA . GLY B 1 205 ? 66.847 -1.572 5.053 1.00 41.64 ? 420 GLY B CA 1 ATOM 3138 C C . GLY B 1 205 ? 65.513 -0.992 4.606 1.00 39.12 ? 420 GLY B C 1 ATOM 3139 O O . GLY B 1 205 ? 65.432 -0.421 3.526 1.00 39.28 ? 420 GLY B O 1 ATOM 3140 N N . ASN B 1 206 ? 64.468 -1.127 5.412 1.00 37.51 ? 421 ASN B N 1 ATOM 3141 C CA . ASN B 1 206 ? 63.180 -0.566 5.031 1.00 36.48 ? 421 ASN B CA 1 ATOM 3142 C C . ASN B 1 206 ? 63.193 0.880 5.411 1.00 34.43 ? 421 ASN B C 1 ATOM 3143 O O . ASN B 1 206 ? 63.715 1.259 6.454 1.00 36.76 ? 421 ASN B O 1 ATOM 3144 C CB . ASN B 1 206 ? 62.025 -1.250 5.747 1.00 38.92 ? 421 ASN B CB 1 ATOM 3145 C CG . ASN B 1 206 ? 61.993 -2.715 5.489 1.00 40.19 ? 421 ASN B CG 1 ATOM 3146 O OD1 . ASN B 1 206 ? 62.296 -3.507 6.372 1.00 40.94 ? 421 ASN B OD1 1 ATOM 3147 N ND2 . ASN B 1 206 ? 61.652 -3.097 4.257 1.00 43.48 ? 421 ASN B ND2 1 ATOM 3148 N N . VAL B 1 207 ? 62.602 1.695 4.565 1.00 29.90 ? 422 VAL B N 1 ATOM 3149 C CA . VAL B 1 207 ? 62.588 3.109 4.812 1.00 25.27 ? 422 VAL B CA 1 ATOM 3150 C C . VAL B 1 207 ? 61.455 3.478 5.708 1.00 27.09 ? 422 VAL B C 1 ATOM 3151 O O . VAL B 1 207 ? 60.419 2.817 5.706 1.00 28.74 ? 422 VAL B O 1 ATOM 3152 C CB . VAL B 1 207 ? 62.447 3.846 3.513 1.00 20.75 ? 422 VAL B CB 1 ATOM 3153 C CG1 . VAL B 1 207 ? 62.477 5.353 3.738 1.00 16.95 ? 422 VAL B CG1 1 ATOM 3154 C CG2 . VAL B 1 207 ? 63.541 3.392 2.603 1.00 20.07 ? 422 VAL B CG2 1 ATOM 3155 N N . PHE B 1 208 ? 61.665 4.531 6.487 1.00 26.13 ? 423 PHE B N 1 ATOM 3156 C CA . PHE B 1 208 ? 60.641 5.038 7.368 1.00 26.03 ? 423 PHE B CA 1 ATOM 3157 C C . PHE B 1 208 ? 60.567 6.523 7.122 1.00 27.95 ? 423 PHE B C 1 ATOM 3158 O O . PHE B 1 208 ? 61.535 7.132 6.709 1.00 26.61 ? 423 PHE B O 1 ATOM 3159 C CB . PHE B 1 208 ? 60.982 4.729 8.805 1.00 24.86 ? 423 PHE B CB 1 ATOM 3160 C CG . PHE B 1 208 ? 60.920 3.269 9.127 1.00 24.95 ? 423 PHE B CG 1 ATOM 3161 C CD1 . PHE B 1 208 ? 61.997 2.440 8.868 1.00 24.17 ? 423 PHE B CD1 1 ATOM 3162 C CD2 . PHE B 1 208 ? 59.773 2.716 9.670 1.00 26.08 ? 423 PHE B CD2 1 ATOM 3163 C CE1 . PHE B 1 208 ? 61.933 1.082 9.146 1.00 22.75 ? 423 PHE B CE1 1 ATOM 3164 C CE2 . PHE B 1 208 ? 59.701 1.355 9.950 1.00 25.19 ? 423 PHE B CE2 1 ATOM 3165 C CZ . PHE B 1 208 ? 60.785 0.541 9.686 1.00 23.14 ? 423 PHE B CZ 1 ATOM 3166 N N . SER B 1 209 ? 59.402 7.106 7.342 1.00 31.49 ? 424 SER B N 1 ATOM 3167 C CA . SER B 1 209 ? 59.231 8.516 7.083 1.00 32.73 ? 424 SER B CA 1 ATOM 3168 C C . SER B 1 209 ? 58.597 9.266 8.200 1.00 34.55 ? 424 SER B C 1 ATOM 3169 O O . SER B 1 209 ? 57.707 8.764 8.876 1.00 36.68 ? 424 SER B O 1 ATOM 3170 C CB . SER B 1 209 ? 58.392 8.721 5.837 1.00 32.86 ? 424 SER B CB 1 ATOM 3171 O OG . SER B 1 209 ? 59.199 8.565 4.694 1.00 37.63 ? 424 SER B OG 1 ATOM 3172 N N . CYS B 1 210 ? 59.074 10.489 8.378 1.00 35.94 ? 425 CYS B N 1 ATOM 3173 C CA . CYS B 1 210 ? 58.575 11.381 9.402 1.00 36.76 ? 425 CYS B CA 1 ATOM 3174 C C . CYS B 1 210 ? 57.825 12.383 8.575 1.00 36.79 ? 425 CYS B C 1 ATOM 3175 O O . CYS B 1 210 ? 58.382 12.955 7.647 1.00 39.07 ? 425 CYS B O 1 ATOM 3176 C CB . CYS B 1 210 ? 59.736 12.062 10.143 1.00 36.18 ? 425 CYS B CB 1 ATOM 3177 S SG . CYS B 1 210 ? 59.193 13.021 11.592 1.00 37.92 ? 425 CYS B SG 1 ATOM 3178 N N . SER B 1 211 ? 56.550 12.564 8.871 1.00 37.59 ? 426 SER B N 1 ATOM 3179 C CA . SER B 1 211 ? 55.754 13.513 8.123 1.00 37.73 ? 426 SER B CA 1 ATOM 3180 C C . SER B 1 211 ? 55.314 14.591 9.069 1.00 39.21 ? 426 SER B C 1 ATOM 3181 O O . SER B 1 211 ? 54.765 14.310 10.138 1.00 41.38 ? 426 SER B O 1 ATOM 3182 C CB . SER B 1 211 ? 54.560 12.815 7.511 1.00 38.29 ? 426 SER B CB 1 ATOM 3183 O OG . SER B 1 211 ? 55.016 11.842 6.582 1.00 42.54 ? 426 SER B OG 1 ATOM 3184 N N . VAL B 1 212 ? 55.577 15.833 8.689 1.00 38.22 ? 427 VAL B N 1 ATOM 3185 C CA . VAL B 1 212 ? 55.220 16.954 9.534 1.00 37.35 ? 427 VAL B CA 1 ATOM 3186 C C . VAL B 1 212 ? 54.256 17.904 8.853 1.00 38.53 ? 427 VAL B C 1 ATOM 3187 O O . VAL B 1 212 ? 54.449 18.267 7.701 1.00 38.21 ? 427 VAL B O 1 ATOM 3188 C CB . VAL B 1 212 ? 56.453 17.764 9.909 1.00 35.75 ? 427 VAL B CB 1 ATOM 3189 C CG1 . VAL B 1 212 ? 56.086 18.768 10.970 1.00 37.40 ? 427 VAL B CG1 1 ATOM 3190 C CG2 . VAL B 1 212 ? 57.559 16.852 10.370 1.00 32.78 ? 427 VAL B CG2 1 ATOM 3191 N N . MET B 1 213 ? 53.215 18.300 9.571 1.00 40.65 ? 428 MET B N 1 ATOM 3192 C CA . MET B 1 213 ? 52.248 19.249 9.047 1.00 43.26 ? 428 MET B CA 1 ATOM 3193 C C . MET B 1 213 ? 52.324 20.474 9.921 1.00 42.54 ? 428 MET B C 1 ATOM 3194 O O . MET B 1 213 ? 52.286 20.365 11.147 1.00 43.92 ? 428 MET B O 1 ATOM 3195 C CB . MET B 1 213 ? 50.842 18.678 9.093 1.00 47.95 ? 428 MET B CB 1 ATOM 3196 C CG . MET B 1 213 ? 50.409 18.058 7.784 1.00 55.34 ? 428 MET B CG 1 ATOM 3197 S SD . MET B 1 213 ? 49.013 16.974 8.056 1.00 63.96 ? 428 MET B SD 1 ATOM 3198 C CE . MET B 1 213 ? 49.871 15.653 9.113 1.00 59.21 ? 428 MET B CE 1 ATOM 3199 N N . HIS B 1 214 ? 52.433 21.634 9.288 1.00 39.76 ? 429 HIS B N 1 ATOM 3200 C CA . HIS B 1 214 ? 52.535 22.892 10.001 1.00 40.34 ? 429 HIS B CA 1 ATOM 3201 C C . HIS B 1 214 ? 52.247 24.045 9.031 1.00 42.61 ? 429 HIS B C 1 ATOM 3202 O O . HIS B 1 214 ? 52.561 23.953 7.842 1.00 45.27 ? 429 HIS B O 1 ATOM 3203 C CB . HIS B 1 214 ? 53.939 23.005 10.581 1.00 39.53 ? 429 HIS B CB 1 ATOM 3204 C CG . HIS B 1 214 ? 54.148 24.219 11.422 1.00 39.23 ? 429 HIS B CG 1 ATOM 3205 N ND1 . HIS B 1 214 ? 54.666 25.388 10.922 1.00 39.47 ? 429 HIS B ND1 1 ATOM 3206 C CD2 . HIS B 1 214 ? 53.886 24.451 12.729 1.00 39.71 ? 429 HIS B CD2 1 ATOM 3207 C CE1 . HIS B 1 214 ? 54.714 26.291 11.884 1.00 40.82 ? 429 HIS B CE1 1 ATOM 3208 N NE2 . HIS B 1 214 ? 54.246 25.746 12.991 1.00 39.75 ? 429 HIS B NE2 1 ATOM 3209 N N . GLU B 1 215 ? 51.662 25.133 9.524 1.00 41.95 ? 430 GLU B N 1 ATOM 3210 C CA . GLU B 1 215 ? 51.322 26.253 8.655 1.00 41.12 ? 430 GLU B CA 1 ATOM 3211 C C . GLU B 1 215 ? 52.478 26.883 7.886 1.00 40.86 ? 430 GLU B C 1 ATOM 3212 O O . GLU B 1 215 ? 52.362 27.147 6.689 1.00 41.02 ? 430 GLU B O 1 ATOM 3213 C CB . GLU B 1 215 ? 50.595 27.327 9.450 1.00 40.84 ? 430 GLU B CB 1 ATOM 3214 C CG . GLU B 1 215 ? 51.456 28.096 10.398 1.00 46.94 ? 430 GLU B CG 1 ATOM 3215 C CD . GLU B 1 215 ? 50.628 28.940 11.345 1.00 50.96 ? 430 GLU B CD 1 ATOM 3216 O OE1 . GLU B 1 215 ? 49.908 28.348 12.177 1.00 54.34 ? 430 GLU B OE1 1 ATOM 3217 O OE2 . GLU B 1 215 ? 50.684 30.188 11.255 1.00 53.09 ? 430 GLU B OE2 1 ATOM 3218 N N . ALA B 1 216 ? 53.594 27.114 8.561 1.00 40.81 ? 431 ALA B N 1 ATOM 3219 C CA . ALA B 1 216 ? 54.752 27.734 7.932 1.00 41.16 ? 431 ALA B CA 1 ATOM 3220 C C . ALA B 1 216 ? 55.483 26.882 6.895 1.00 42.42 ? 431 ALA B C 1 ATOM 3221 O O . ALA B 1 216 ? 56.438 27.342 6.282 1.00 41.73 ? 431 ALA B O 1 ATOM 3222 C CB . ALA B 1 216 ? 55.718 28.174 8.998 1.00 41.60 ? 431 ALA B CB 1 ATOM 3223 N N . LEU B 1 217 ? 55.043 25.646 6.695 1.00 44.43 ? 432 LEU B N 1 ATOM 3224 C CA . LEU B 1 217 ? 55.681 24.756 5.722 1.00 47.48 ? 432 LEU B CA 1 ATOM 3225 C C . LEU B 1 217 ? 54.968 24.855 4.381 1.00 51.04 ? 432 LEU B C 1 ATOM 3226 O O . LEU B 1 217 ? 53.736 24.864 4.335 1.00 52.49 ? 432 LEU B O 1 ATOM 3227 C CB . LEU B 1 217 ? 55.619 23.300 6.212 1.00 45.68 ? 432 LEU B CB 1 ATOM 3228 C CG . LEU B 1 217 ? 56.522 22.841 7.359 1.00 42.14 ? 432 LEU B CG 1 ATOM 3229 C CD1 . LEU B 1 217 ? 56.029 21.530 7.916 1.00 42.75 ? 432 LEU B CD1 1 ATOM 3230 C CD2 . LEU B 1 217 ? 57.927 22.685 6.855 1.00 40.90 ? 432 LEU B CD2 1 ATOM 3231 N N . HIS B 1 218 ? 55.721 24.914 3.286 1.00 54.54 ? 433 HIS B N 1 ATOM 3232 C CA . HIS B 1 218 ? 55.077 25.005 1.979 1.00 57.17 ? 433 HIS B CA 1 ATOM 3233 C C . HIS B 1 218 ? 54.062 23.889 1.839 1.00 56.51 ? 433 HIS B C 1 ATOM 3234 O O . HIS B 1 218 ? 54.354 22.741 2.148 1.00 56.36 ? 433 HIS B O 1 ATOM 3235 C CB . HIS B 1 218 ? 56.082 24.896 0.832 1.00 61.77 ? 433 HIS B CB 1 ATOM 3236 C CG . HIS B 1 218 ? 55.428 24.775 -0.511 1.00 68.84 ? 433 HIS B CG 1 ATOM 3237 N ND1 . HIS B 1 218 ? 54.587 25.745 -1.017 1.00 73.31 ? 433 HIS B ND1 1 ATOM 3238 C CD2 . HIS B 1 218 ? 55.423 23.766 -1.417 1.00 71.62 ? 433 HIS B CD2 1 ATOM 3239 C CE1 . HIS B 1 218 ? 54.089 25.338 -2.172 1.00 74.42 ? 433 HIS B CE1 1 ATOM 3240 N NE2 . HIS B 1 218 ? 54.580 24.139 -2.437 1.00 73.87 ? 433 HIS B NE2 1 ATOM 3241 N N . ASN B 1 219 ? 52.865 24.226 1.375 1.00 57.33 ? 434 ASN B N 1 ATOM 3242 C CA . ASN B 1 219 ? 51.826 23.227 1.204 1.00 57.14 ? 434 ASN B CA 1 ATOM 3243 C C . ASN B 1 219 ? 51.508 22.542 2.549 1.00 55.50 ? 434 ASN B C 1 ATOM 3244 O O . ASN B 1 219 ? 51.022 21.411 2.576 1.00 53.16 ? 434 ASN B O 1 ATOM 3245 C CB . ASN B 1 219 ? 52.288 22.206 0.157 1.00 60.26 ? 434 ASN B CB 1 ATOM 3246 C CG . ASN B 1 219 ? 51.278 21.095 -0.072 1.00 64.48 ? 434 ASN B CG 1 ATOM 3247 O OD1 . ASN B 1 219 ? 50.115 21.356 -0.387 1.00 68.33 ? 434 ASN B OD1 1 ATOM 3248 N ND2 . ASN B 1 219 ? 51.721 19.844 0.076 1.00 64.30 ? 434 ASN B ND2 1 ATOM 3249 N N . HIS B 1 220 ? 51.782 23.245 3.655 1.00 54.11 ? 435 HIS B N 1 ATOM 3250 C CA . HIS B 1 220 ? 51.533 22.750 5.021 1.00 51.73 ? 435 HIS B CA 1 ATOM 3251 C C . HIS B 1 220 ? 52.008 21.316 5.262 1.00 49.45 ? 435 HIS B C 1 ATOM 3252 O O . HIS B 1 220 ? 51.390 20.573 6.042 1.00 48.76 ? 435 HIS B O 1 ATOM 3253 C CB . HIS B 1 220 ? 50.035 22.778 5.354 1.00 53.44 ? 435 HIS B CB 1 ATOM 3254 C CG . HIS B 1 220 ? 49.402 24.125 5.241 1.00 55.08 ? 435 HIS B CG 1 ATOM 3255 N ND1 . HIS B 1 220 ? 49.904 25.238 5.878 1.00 55.89 ? 435 HIS B ND1 1 ATOM 3256 C CD2 . HIS B 1 220 ? 48.268 24.523 4.620 1.00 55.49 ? 435 HIS B CD2 1 ATOM 3257 C CE1 . HIS B 1 220 ? 49.103 26.266 5.657 1.00 56.40 ? 435 HIS B CE1 1 ATOM 3258 N NE2 . HIS B 1 220 ? 48.102 25.858 4.897 1.00 56.69 ? 435 HIS B NE2 1 ATOM 3259 N N . TYR B 1 221 ? 53.092 20.908 4.617 1.00 44.62 ? 436 TYR B N 1 ATOM 3260 C CA . TYR B 1 221 ? 53.521 19.542 4.809 1.00 40.09 ? 436 TYR B CA 1 ATOM 3261 C C . TYR B 1 221 ? 54.856 19.203 4.228 1.00 40.45 ? 436 TYR B C 1 ATOM 3262 O O . TYR B 1 221 ? 55.107 19.498 3.066 1.00 45.27 ? 436 TYR B O 1 ATOM 3263 C CB . TYR B 1 221 ? 52.484 18.609 4.207 1.00 32.97 ? 436 TYR B CB 1 ATOM 3264 C CG . TYR B 1 221 ? 52.946 17.187 4.039 1.00 30.83 ? 436 TYR B CG 1 ATOM 3265 C CD1 . TYR B 1 221 ? 53.650 16.793 2.921 1.00 28.97 ? 436 TYR B CD1 1 ATOM 3266 C CD2 . TYR B 1 221 ? 52.662 16.228 5.005 1.00 32.07 ? 436 TYR B CD2 1 ATOM 3267 C CE1 . TYR B 1 221 ? 54.058 15.478 2.763 1.00 31.82 ? 436 TYR B CE1 1 ATOM 3268 C CE2 . TYR B 1 221 ? 53.064 14.914 4.862 1.00 30.20 ? 436 TYR B CE2 1 ATOM 3269 C CZ . TYR B 1 221 ? 53.761 14.539 3.740 1.00 32.10 ? 436 TYR B CZ 1 ATOM 3270 O OH . TYR B 1 221 ? 54.158 13.221 3.594 1.00 33.36 ? 436 TYR B OH 1 ATOM 3271 N N . THR B 1 222 ? 55.709 18.569 5.025 1.00 37.66 ? 437 THR B N 1 ATOM 3272 C CA . THR B 1 222 ? 57.006 18.123 4.536 1.00 35.97 ? 437 THR B CA 1 ATOM 3273 C C . THR B 1 222 ? 57.237 16.680 4.985 1.00 36.59 ? 437 THR B C 1 ATOM 3274 O O . THR B 1 222 ? 56.512 16.162 5.827 1.00 40.20 ? 437 THR B O 1 ATOM 3275 C CB . THR B 1 222 ? 58.140 18.990 5.054 1.00 33.81 ? 437 THR B CB 1 ATOM 3276 O OG1 . THR B 1 222 ? 59.366 18.504 4.517 1.00 33.45 ? 437 THR B OG1 1 ATOM 3277 C CG2 . THR B 1 222 ? 58.214 18.938 6.556 1.00 32.63 ? 437 THR B CG2 1 ATOM 3278 N N . GLN B 1 223 ? 58.237 16.022 4.432 1.00 34.40 ? 438 GLN B N 1 ATOM 3279 C CA . GLN B 1 223 ? 58.498 14.652 4.826 1.00 34.75 ? 438 GLN B CA 1 ATOM 3280 C C . GLN B 1 223 ? 59.993 14.336 4.831 1.00 36.15 ? 438 GLN B C 1 ATOM 3281 O O . GLN B 1 223 ? 60.748 14.883 4.022 1.00 38.53 ? 438 GLN B O 1 ATOM 3282 C CB . GLN B 1 223 ? 57.764 13.700 3.889 1.00 32.09 ? 438 GLN B CB 1 ATOM 3283 C CG . GLN B 1 223 ? 58.120 12.252 4.128 1.00 34.09 ? 438 GLN B CG 1 ATOM 3284 C CD . GLN B 1 223 ? 57.255 11.286 3.334 1.00 35.16 ? 438 GLN B CD 1 ATOM 3285 O OE1 . GLN B 1 223 ? 57.480 11.055 2.142 1.00 31.86 ? 438 GLN B OE1 1 ATOM 3286 N NE2 . GLN B 1 223 ? 56.247 10.720 3.999 1.00 34.96 ? 438 GLN B NE2 1 ATOM 3287 N N . LYS B 1 224 ? 60.420 13.462 5.739 1.00 34.71 ? 439 LYS B N 1 ATOM 3288 C CA . LYS B 1 224 ? 61.830 13.074 5.834 1.00 34.83 ? 439 LYS B CA 1 ATOM 3289 C C . LYS B 1 224 ? 61.908 11.577 6.052 1.00 35.98 ? 439 LYS B C 1 ATOM 3290 O O . LYS B 1 224 ? 61.355 11.051 7.013 1.00 36.72 ? 439 LYS B O 1 ATOM 3291 C CB . LYS B 1 224 ? 62.514 13.776 7.007 1.00 34.88 ? 439 LYS B CB 1 ATOM 3292 C CG . LYS B 1 224 ? 63.527 14.855 6.645 1.00 35.76 ? 439 LYS B CG 1 ATOM 3293 C CD . LYS B 1 224 ? 64.754 14.285 5.949 1.00 37.15 ? 439 LYS B CD 1 ATOM 3294 C CE . LYS B 1 224 ? 65.842 15.354 5.687 1.00 36.30 ? 439 LYS B CE 1 ATOM 3295 N NZ . LYS B 1 224 ? 66.423 15.978 6.918 1.00 32.00 ? 439 LYS B NZ 1 ATOM 3296 N N . SER B 1 225 ? 62.599 10.889 5.157 1.00 36.58 ? 440 SER B N 1 ATOM 3297 C CA . SER B 1 225 ? 62.743 9.448 5.250 1.00 36.74 ? 440 SER B CA 1 ATOM 3298 C C . SER B 1 225 ? 64.044 9.117 5.962 1.00 37.61 ? 440 SER B C 1 ATOM 3299 O O . SER B 1 225 ? 64.986 9.906 5.953 1.00 36.50 ? 440 SER B O 1 ATOM 3300 C CB . SER B 1 225 ? 62.743 8.814 3.849 1.00 38.65 ? 440 SER B CB 1 ATOM 3301 O OG . SER B 1 225 ? 61.500 8.984 3.183 1.00 37.84 ? 440 SER B OG 1 ATOM 3302 N N . LEU B 1 226 ? 64.076 7.935 6.571 1.00 38.68 ? 441 LEU B N 1 ATOM 3303 C CA . LEU B 1 226 ? 65.225 7.440 7.316 1.00 38.97 ? 441 LEU B CA 1 ATOM 3304 C C . LEU B 1 226 ? 65.383 5.961 7.001 1.00 39.76 ? 441 LEU B C 1 ATOM 3305 O O . LEU B 1 226 ? 64.393 5.250 6.925 1.00 42.25 ? 441 LEU B O 1 ATOM 3306 C CB . LEU B 1 226 ? 64.982 7.624 8.817 1.00 36.85 ? 441 LEU B CB 1 ATOM 3307 C CG . LEU B 1 226 ? 66.100 7.144 9.741 1.00 37.85 ? 441 LEU B CG 1 ATOM 3308 C CD1 . LEU B 1 226 ? 67.365 7.891 9.412 1.00 37.65 ? 441 LEU B CD1 1 ATOM 3309 C CD2 . LEU B 1 226 ? 65.729 7.374 11.193 1.00 39.57 ? 441 LEU B CD2 1 ATOM 3310 N N . SER B 1 227 ? 66.609 5.490 6.807 1.00 40.58 ? 442 SER B N 1 ATOM 3311 C CA . SER B 1 227 ? 66.809 4.074 6.520 1.00 41.78 ? 442 SER B CA 1 ATOM 3312 C C . SER B 1 227 ? 68.266 3.661 6.420 1.00 44.24 ? 442 SER B C 1 ATOM 3313 O O . SER B 1 227 ? 69.124 4.435 5.994 1.00 45.34 ? 442 SER B O 1 ATOM 3314 C CB . SER B 1 227 ? 66.111 3.691 5.223 1.00 41.75 ? 442 SER B CB 1 ATOM 3315 O OG . SER B 1 227 ? 66.696 4.366 4.134 1.00 41.18 ? 442 SER B OG 1 ATOM 3316 N N . LEU B 1 228 ? 68.531 2.418 6.802 1.00 45.92 ? 443 LEU B N 1 ATOM 3317 C CA . LEU B 1 228 ? 69.872 1.874 6.763 1.00 46.78 ? 443 LEU B CA 1 ATOM 3318 C C . LEU B 1 228 ? 70.369 1.859 5.338 1.00 50.84 ? 443 LEU B C 1 ATOM 3319 O O . LEU B 1 228 ? 69.916 1.063 4.522 1.00 50.95 ? 443 LEU B O 1 ATOM 3320 C CB . LEU B 1 228 ? 69.877 0.461 7.325 1.00 43.91 ? 443 LEU B CB 1 ATOM 3321 C CG . LEU B 1 228 ? 71.239 -0.158 7.635 1.00 41.46 ? 443 LEU B CG 1 ATOM 3322 C CD1 . LEU B 1 228 ? 72.070 0.816 8.415 1.00 37.90 ? 443 LEU B CD1 1 ATOM 3323 C CD2 . LEU B 1 228 ? 71.047 -1.439 8.424 1.00 40.09 ? 443 LEU B CD2 1 ATOM 3324 N N . SER B 1 229 ? 71.298 2.759 5.037 1.00 56.90 ? 444 SER B N 1 ATOM 3325 C CA . SER B 1 229 ? 71.874 2.848 3.695 1.00 60.92 ? 444 SER B CA 1 ATOM 3326 C C . SER B 1 229 ? 72.713 1.578 3.482 1.00 60.30 ? 444 SER B C 1 ATOM 3327 O O . SER B 1 229 ? 73.641 1.300 4.246 1.00 60.12 ? 444 SER B O 1 ATOM 3328 C CB . SER B 1 229 ? 72.746 4.120 3.581 1.00 64.42 ? 444 SER B CB 1 ATOM 3329 O OG . SER B 1 229 ? 72.980 4.509 2.229 1.00 67.01 ? 444 SER B OG 1 ATOM 3330 N N . PRO B 1 230 ? 72.378 0.785 2.450 1.00 60.11 ? 445 PRO B N 1 ATOM 3331 C CA . PRO B 1 230 ? 73.063 -0.468 2.100 1.00 60.32 ? 445 PRO B CA 1 ATOM 3332 C C . PRO B 1 230 ? 74.579 -0.367 1.836 1.00 60.09 ? 445 PRO B C 1 ATOM 3333 O O . PRO B 1 230 ? 74.973 0.113 0.750 1.00 60.31 ? 445 PRO B O 1 ATOM 3334 C CB . PRO B 1 230 ? 72.271 -0.961 0.880 1.00 59.69 ? 445 PRO B CB 1 ATOM 3335 C CG . PRO B 1 230 ? 71.741 0.305 0.274 1.00 59.02 ? 445 PRO B CG 1 ATOM 3336 C CD . PRO B 1 230 ? 71.312 1.087 1.479 1.00 59.83 ? 445 PRO B CD 1 ATOM 3337 N N . GLY B 1 231 ? 75.364 -0.766 2.724 1.00 58.34 ? 446 GLY B N 1 ATOM 3338 N N . GLN C 2 12 ? 100.080 4.588 18.079 1.00 78.33 ? 1 GLN H N 1 ATOM 3339 C CA . GLN C 2 12 ? 98.790 5.309 18.275 1.00 79.26 ? 1 GLN H CA 1 ATOM 3340 C C . GLN C 2 12 ? 97.994 4.790 19.470 1.00 78.48 ? 1 GLN H C 1 ATOM 3341 O O . GLN C 2 12 ? 98.147 5.288 20.580 1.00 78.99 ? 1 GLN H O 1 ATOM 3342 C CB . GLN C 2 12 ? 97.935 5.205 17.014 1.00 82.02 ? 1 GLN H CB 1 ATOM 3343 C CG . GLN C 2 12 ? 96.499 5.721 17.175 1.00 85.13 ? 1 GLN H CG 1 ATOM 3344 C CD . GLN C 2 12 ? 96.423 7.112 17.793 1.00 86.88 ? 1 GLN H CD 1 ATOM 3345 O OE1 . GLN C 2 12 ? 96.683 7.295 18.989 1.00 86.66 ? 1 GLN H OE1 1 ATOM 3346 N NE2 . GLN C 2 12 ? 96.069 8.102 16.976 1.00 87.87 ? 1 GLN H NE2 1 ATOM 3347 N N . LEU C 2 13 ? 97.132 3.805 19.242 1.00 76.88 ? 2 LEU H N 1 ATOM 3348 C CA . LEU C 2 13 ? 96.331 3.237 20.321 1.00 75.73 ? 2 LEU H CA 1 ATOM 3349 C C . LEU C 2 13 ? 96.800 1.819 20.606 1.00 75.76 ? 2 LEU H C 1 ATOM 3350 O O . LEU C 2 13 ? 97.029 1.042 19.679 1.00 75.41 ? 2 LEU H O 1 ATOM 3351 C CB . LEU C 2 13 ? 94.850 3.203 19.941 1.00 74.81 ? 2 LEU H CB 1 ATOM 3352 C CG . LEU C 2 13 ? 93.963 2.424 20.922 1.00 74.04 ? 2 LEU H CG 1 ATOM 3353 C CD1 . LEU C 2 13 ? 93.675 3.289 22.141 1.00 74.04 ? 2 LEU H CD1 1 ATOM 3354 C CD2 . LEU C 2 13 ? 92.669 2.006 20.242 1.00 72.54 ? 2 LEU H CD2 1 ATOM 3355 N N . GLN C 2 14 ? 96.930 1.476 21.885 1.00 75.29 ? 3 GLN H N 1 ATOM 3356 C CA . GLN C 2 14 ? 97.377 0.141 22.253 1.00 75.51 ? 3 GLN H CA 1 ATOM 3357 C C . GLN C 2 14 ? 96.768 -0.337 23.561 1.00 74.20 ? 3 GLN H C 1 ATOM 3358 O O . GLN C 2 14 ? 96.389 0.465 24.413 1.00 74.89 ? 3 GLN H O 1 ATOM 3359 C CB . GLN C 2 14 ? 98.900 0.123 22.369 1.00 78.16 ? 3 GLN H CB 1 ATOM 3360 C CG . GLN C 2 14 ? 99.620 0.653 21.138 1.00 81.35 ? 3 GLN H CG 1 ATOM 3361 C CD . GLN C 2 14 ? 101.127 0.664 21.293 1.00 82.09 ? 3 GLN H CD 1 ATOM 3362 O OE1 . GLN C 2 14 ? 101.670 1.338 22.173 1.00 82.89 ? 3 GLN H OE1 1 ATOM 3363 N NE2 . GLN C 2 14 ? 101.812 -0.083 20.433 1.00 81.87 ? 3 GLN H NE2 1 ATOM 3364 N N . LEU C 2 15 ? 96.677 -1.651 23.712 1.00 71.82 ? 4 LEU H N 1 ATOM 3365 C CA . LEU C 2 15 ? 96.134 -2.245 24.924 1.00 71.65 ? 4 LEU H CA 1 ATOM 3366 C C . LEU C 2 15 ? 97.068 -3.362 25.395 1.00 71.82 ? 4 LEU H C 1 ATOM 3367 O O . LEU C 2 15 ? 97.435 -4.255 24.627 1.00 71.98 ? 4 LEU H O 1 ATOM 3368 C CB . LEU C 2 15 ? 94.720 -2.795 24.675 1.00 72.43 ? 4 LEU H CB 1 ATOM 3369 C CG . LEU C 2 15 ? 93.552 -1.820 24.445 1.00 71.60 ? 4 LEU H CG 1 ATOM 3370 C CD1 . LEU C 2 15 ? 93.773 -1.013 23.181 1.00 71.03 ? 4 LEU H CD1 1 ATOM 3371 C CD2 . LEU C 2 15 ? 92.258 -2.602 24.338 1.00 70.59 ? 4 LEU H CD2 1 ATOM 3372 N N . GLN C 2 16 ? 97.446 -3.306 26.668 1.00 71.52 ? 5 GLN H N 1 ATOM 3373 C CA . GLN C 2 16 ? 98.357 -4.282 27.243 1.00 70.94 ? 5 GLN H CA 1 ATOM 3374 C C . GLN C 2 16 ? 97.739 -5.038 28.402 1.00 70.06 ? 5 GLN H C 1 ATOM 3375 O O . GLN C 2 16 ? 97.344 -4.440 29.399 1.00 69.76 ? 5 GLN H O 1 ATOM 3376 C CB . GLN C 2 16 ? 99.628 -3.566 27.725 1.00 73.49 ? 5 GLN H CB 1 ATOM 3377 C CG . GLN C 2 16 ? 100.680 -4.472 28.350 1.00 75.16 ? 5 GLN H CG 1 ATOM 3378 C CD . GLN C 2 16 ? 101.235 -5.476 27.363 1.00 76.60 ? 5 GLN H CD 1 ATOM 3379 O OE1 . GLN C 2 16 ? 101.149 -6.690 27.576 1.00 75.70 ? 5 GLN H OE1 1 ATOM 3380 N NE2 . GLN C 2 16 ? 101.806 -4.975 26.267 1.00 77.16 ? 5 GLN H NE2 1 ATOM 3381 N N . GLU C 2 17 ? 97.658 -6.356 28.272 1.00 69.88 ? 6 GLU H N 1 ATOM 3382 C CA . GLU C 2 17 ? 97.108 -7.181 29.336 1.00 71.21 ? 6 GLU H CA 1 ATOM 3383 C C . GLU C 2 17 ? 98.168 -7.313 30.426 1.00 72.01 ? 6 GLU H C 1 ATOM 3384 O O . GLU C 2 17 ? 99.360 -7.197 30.149 1.00 72.92 ? 6 GLU H O 1 ATOM 3385 C CB . GLU C 2 17 ? 96.752 -8.579 28.820 1.00 71.87 ? 6 GLU H CB 1 ATOM 3386 C CG . GLU C 2 17 ? 95.800 -8.626 27.639 1.00 73.79 ? 6 GLU H CG 1 ATOM 3387 C CD . GLU C 2 17 ? 96.500 -8.440 26.308 1.00 75.87 ? 6 GLU H CD 1 ATOM 3388 O OE1 . GLU C 2 17 ? 95.818 -8.513 25.263 1.00 77.84 ? 6 GLU H OE1 1 ATOM 3389 O OE2 . GLU C 2 17 ? 97.730 -8.222 26.300 1.00 77.09 ? 6 GLU H OE2 1 ATOM 3390 N N . SER C 2 18 ? 97.729 -7.557 31.658 1.00 72.52 ? 7 SER H N 1 ATOM 3391 C CA . SER C 2 18 ? 98.627 -7.716 32.800 1.00 72.89 ? 7 SER H CA 1 ATOM 3392 C C . SER C 2 18 ? 98.003 -8.692 33.776 1.00 73.99 ? 7 SER H C 1 ATOM 3393 O O . SER C 2 18 ? 96.854 -8.520 34.175 1.00 74.18 ? 7 SER H O 1 ATOM 3394 C CB . SER C 2 18 ? 98.832 -6.386 33.520 1.00 72.39 ? 7 SER H CB 1 ATOM 3395 O OG . SER C 2 18 ? 99.401 -5.420 32.661 1.00 74.95 ? 7 SER H OG 1 ATOM 3396 N N . GLY C 2 19 ? 98.750 -9.713 34.172 1.00 75.24 ? 8 GLY H N 1 ATOM 3397 C CA . GLY C 2 19 ? 98.184 -10.657 35.114 1.00 77.20 ? 8 GLY H CA 1 ATOM 3398 C C . GLY C 2 19 ? 98.998 -11.887 35.457 1.00 78.50 ? 8 GLY H C 1 ATOM 3399 O O . GLY C 2 19 ? 99.952 -12.243 34.760 1.00 78.57 ? 8 GLY H O 1 ATOM 3400 N N . PRO C 2 20 ? 98.625 -12.564 36.552 1.00 79.20 ? 9 PRO H N 1 ATOM 3401 C CA . PRO C 2 20 ? 99.304 -13.773 37.015 1.00 80.01 ? 9 PRO H CA 1 ATOM 3402 C C . PRO C 2 20 ? 99.249 -14.876 35.967 1.00 80.76 ? 9 PRO H C 1 ATOM 3403 O O . PRO C 2 20 ? 98.174 -15.393 35.666 1.00 81.79 ? 9 PRO H O 1 ATOM 3404 C CB . PRO C 2 20 ? 98.526 -14.136 38.279 1.00 79.81 ? 9 PRO H CB 1 ATOM 3405 C CG . PRO C 2 20 ? 97.147 -13.614 37.985 1.00 79.03 ? 9 PRO H CG 1 ATOM 3406 C CD . PRO C 2 20 ? 97.459 -12.266 37.402 1.00 78.94 ? 9 PRO H CD 1 ATOM 3407 N N . GLY C 2 21 ? 100.407 -15.228 35.412 1.00 80.82 ? 10 GLY H N 1 ATOM 3408 C CA . GLY C 2 21 ? 100.460 -16.278 34.409 1.00 79.39 ? 10 GLY H CA 1 ATOM 3409 C C . GLY C 2 21 ? 99.962 -17.608 34.949 1.00 78.92 ? 10 GLY H C 1 ATOM 3410 O O . GLY C 2 21 ? 99.922 -18.606 34.225 1.00 78.36 ? 10 GLY H O 1 ATOM 3411 N N . LEU C 2 22 ? 99.579 -17.623 36.223 1.00 78.88 ? 11 LEU H N 1 ATOM 3412 C CA . LEU C 2 22 ? 99.083 -18.840 36.850 1.00 80.02 ? 11 LEU H CA 1 ATOM 3413 C C . LEU C 2 22 ? 97.907 -18.639 37.808 1.00 79.53 ? 11 LEU H C 1 ATOM 3414 O O . LEU C 2 22 ? 97.756 -17.582 38.421 1.00 78.57 ? 11 LEU H O 1 ATOM 3415 C CB . LEU C 2 22 ? 100.227 -19.551 37.576 1.00 81.72 ? 11 LEU H CB 1 ATOM 3416 C CG . LEU C 2 22 ? 101.161 -20.340 36.653 1.00 83.36 ? 11 LEU H CG 1 ATOM 3417 C CD1 . LEU C 2 22 ? 102.374 -20.853 37.427 1.00 83.26 ? 11 LEU H CD1 1 ATOM 3418 C CD2 . LEU C 2 22 ? 100.375 -21.493 36.031 1.00 83.34 ? 11 LEU H CD2 1 ATOM 3419 N N . VAL C 2 23 ? 97.079 -19.675 37.917 1.00 79.26 ? 12 VAL H N 1 ATOM 3420 C CA . VAL C 2 23 ? 95.900 -19.673 38.780 1.00 79.73 ? 12 VAL H CA 1 ATOM 3421 C C . VAL C 2 23 ? 95.551 -21.117 39.147 1.00 80.26 ? 12 VAL H C 1 ATOM 3422 O O . VAL C 2 23 ? 95.341 -21.955 38.274 1.00 80.20 ? 12 VAL H O 1 ATOM 3423 C CB . VAL C 2 23 ? 94.676 -19.030 38.069 1.00 79.64 ? 12 VAL H CB 1 ATOM 3424 C CG1 . VAL C 2 23 ? 93.432 -19.222 38.904 1.00 79.19 ? 12 VAL H CG1 1 ATOM 3425 C CG2 . VAL C 2 23 ? 94.913 -17.544 37.844 1.00 79.22 ? 12 VAL H CG2 1 ATOM 3426 N N . LYS C 2 24 ? 95.486 -21.404 40.441 1.00 80.58 ? 13 LYS H N 1 ATOM 3427 C CA . LYS C 2 24 ? 95.181 -22.748 40.909 1.00 81.33 ? 13 LYS H CA 1 ATOM 3428 C C . LYS C 2 24 ? 93.680 -22.963 40.954 1.00 79.71 ? 13 LYS H C 1 ATOM 3429 O O . LYS C 2 24 ? 92.934 -22.041 41.239 1.00 78.91 ? 13 LYS H O 1 ATOM 3430 C CB . LYS C 2 24 ? 95.794 -22.957 42.297 1.00 84.77 ? 13 LYS H CB 1 ATOM 3431 C CG . LYS C 2 24 ? 97.308 -22.709 42.337 1.00 87.90 ? 13 LYS H CG 1 ATOM 3432 C CD . LYS C 2 24 ? 97.841 -22.566 43.763 1.00 90.17 ? 13 LYS H CD 1 ATOM 3433 C CE . LYS C 2 24 ? 99.267 -22.002 43.768 1.00 91.50 ? 13 LYS H CE 1 ATOM 3434 N NZ . LYS C 2 24 ? 99.813 -21.789 45.145 1.00 91.80 ? 13 LYS H NZ 1 ATOM 3435 N N . PRO C 2 25 ? 93.223 -24.192 40.676 1.00 79.72 ? 14 PRO H N 1 ATOM 3436 C CA . PRO C 2 25 ? 91.801 -24.552 40.676 1.00 80.07 ? 14 PRO H CA 1 ATOM 3437 C C . PRO C 2 25 ? 90.980 -23.889 41.771 1.00 80.70 ? 14 PRO H C 1 ATOM 3438 O O . PRO C 2 25 ? 91.496 -23.570 42.837 1.00 80.48 ? 14 PRO H O 1 ATOM 3439 C CB . PRO C 2 25 ? 91.834 -26.066 40.804 1.00 79.44 ? 14 PRO H CB 1 ATOM 3440 C CG . PRO C 2 25 ? 93.033 -26.417 39.987 1.00 80.06 ? 14 PRO H CG 1 ATOM 3441 C CD . PRO C 2 25 ? 94.057 -25.384 40.436 1.00 79.93 ? 14 PRO H CD 1 ATOM 3442 N N . SER C 2 26 ? 89.696 -23.687 41.486 1.00 82.29 ? 15 SER H N 1 ATOM 3443 C CA . SER C 2 26 ? 88.758 -23.047 42.410 1.00 83.56 ? 15 SER H CA 1 ATOM 3444 C C . SER C 2 26 ? 89.078 -21.581 42.721 1.00 82.99 ? 15 SER H C 1 ATOM 3445 O O . SER C 2 26 ? 88.220 -20.853 43.223 1.00 82.73 ? 15 SER H O 1 ATOM 3446 C CB . SER C 2 26 ? 88.668 -23.823 43.723 1.00 84.56 ? 15 SER H CB 1 ATOM 3447 O OG . SER C 2 26 ? 87.733 -23.205 44.594 1.00 86.09 ? 15 SER H OG 1 ATOM 3448 N N . GLU C 2 27 ? 90.306 -21.150 42.441 1.00 82.20 ? 16 GLU H N 1 ATOM 3449 C CA . GLU C 2 27 ? 90.677 -19.764 42.687 1.00 82.78 ? 16 GLU H CA 1 ATOM 3450 C C . GLU C 2 27 ? 89.917 -18.846 41.730 1.00 82.69 ? 16 GLU H C 1 ATOM 3451 O O . GLU C 2 27 ? 88.939 -19.255 41.095 1.00 83.11 ? 16 GLU H O 1 ATOM 3452 C CB . GLU C 2 27 ? 92.184 -19.549 42.494 1.00 84.28 ? 16 GLU H CB 1 ATOM 3453 C CG . GLU C 2 27 ? 93.068 -20.019 43.645 1.00 86.91 ? 16 GLU H CG 1 ATOM 3454 C CD . GLU C 2 27 ? 94.528 -19.611 43.459 1.00 88.23 ? 16 GLU H CD 1 ATOM 3455 O OE1 . GLU C 2 27 ? 95.100 -19.927 42.393 1.00 88.52 ? 16 GLU H OE1 1 ATOM 3456 O OE2 . GLU C 2 27 ? 95.103 -18.978 44.375 1.00 88.18 ? 16 GLU H OE2 1 ATOM 3457 N N . THR C 2 28 ? 90.376 -17.603 41.631 1.00 81.45 ? 17 THR H N 1 ATOM 3458 C CA . THR C 2 28 ? 89.752 -16.620 40.756 1.00 79.95 ? 17 THR H CA 1 ATOM 3459 C C . THR C 2 28 ? 90.820 -15.849 39.977 1.00 77.97 ? 17 THR H C 1 ATOM 3460 O O . THR C 2 28 ? 91.690 -15.203 40.566 1.00 77.18 ? 17 THR H O 1 ATOM 3461 C CB . THR C 2 28 ? 88.886 -15.617 41.567 1.00 80.75 ? 17 THR H CB 1 ATOM 3462 O OG1 . THR C 2 28 ? 89.729 -14.816 42.402 1.00 81.77 ? 17 THR H OG1 1 ATOM 3463 C CG2 . THR C 2 28 ? 87.892 -16.359 42.451 1.00 80.75 ? 17 THR H CG2 1 ATOM 3464 N N . LEU C 2 29 ? 90.756 -15.932 38.652 1.00 75.77 ? 18 LEU H N 1 ATOM 3465 C CA . LEU C 2 29 ? 91.708 -15.239 37.794 1.00 73.66 ? 18 LEU H CA 1 ATOM 3466 C C . LEU C 2 29 ? 91.544 -13.731 37.904 1.00 71.50 ? 18 LEU H C 1 ATOM 3467 O O . LEU C 2 29 ? 90.476 -13.243 38.261 1.00 72.45 ? 18 LEU H O 1 ATOM 3468 C CB . LEU C 2 29 ? 91.516 -15.663 36.342 1.00 74.60 ? 18 LEU H CB 1 ATOM 3469 C CG . LEU C 2 29 ? 92.339 -14.858 35.337 1.00 75.99 ? 18 LEU H CG 1 ATOM 3470 C CD1 . LEU C 2 29 ? 93.809 -14.845 35.751 1.00 76.94 ? 18 LEU H CD1 1 ATOM 3471 C CD2 . LEU C 2 29 ? 92.163 -15.458 33.954 1.00 76.69 ? 18 LEU H CD2 1 ATOM 3472 N N . SER C 2 30 ? 92.600 -12.992 37.594 1.00 68.04 ? 19 SER H N 1 ATOM 3473 C CA . SER C 2 30 ? 92.526 -11.546 37.673 1.00 66.70 ? 19 SER H CA 1 ATOM 3474 C C . SER C 2 30 ? 93.516 -10.845 36.759 1.00 66.05 ? 19 SER H C 1 ATOM 3475 O O . SER C 2 30 ? 94.720 -10.864 37.001 1.00 66.07 ? 19 SER H O 1 ATOM 3476 C CB . SER C 2 30 ? 92.746 -11.088 39.113 1.00 66.19 ? 19 SER H CB 1 ATOM 3477 O OG . SER C 2 30 ? 92.946 -9.684 39.165 1.00 66.21 ? 19 SER H OG 1 ATOM 3478 N N . LEU C 2 31 ? 92.994 -10.206 35.716 1.00 65.20 ? 20 LEU H N 1 ATOM 3479 C CA . LEU C 2 31 ? 93.830 -9.496 34.761 1.00 64.35 ? 20 LEU H CA 1 ATOM 3480 C C . LEU C 2 31 ? 93.484 -8.024 34.720 1.00 62.47 ? 20 LEU H C 1 ATOM 3481 O O . LEU C 2 31 ? 92.492 -7.603 35.313 1.00 61.73 ? 20 LEU H O 1 ATOM 3482 C CB . LEU C 2 31 ? 93.654 -10.084 33.366 1.00 65.78 ? 20 LEU H CB 1 ATOM 3483 C CG . LEU C 2 31 ? 94.009 -11.557 33.217 1.00 67.24 ? 20 LEU H CG 1 ATOM 3484 C CD1 . LEU C 2 31 ? 93.704 -11.997 31.795 1.00 69.52 ? 20 LEU H CD1 1 ATOM 3485 C CD2 . LEU C 2 31 ? 95.479 -11.769 33.551 1.00 68.13 ? 20 LEU H CD2 1 ATOM 3486 N N . THR C 2 32 ? 94.312 -7.255 34.015 1.00 59.86 ? 21 THR H N 1 ATOM 3487 C CA . THR C 2 32 ? 94.110 -5.821 33.866 1.00 59.33 ? 21 THR H CA 1 ATOM 3488 C C . THR C 2 32 ? 94.612 -5.371 32.497 1.00 60.32 ? 21 THR H C 1 ATOM 3489 O O . THR C 2 32 ? 95.591 -5.908 31.973 1.00 60.65 ? 21 THR H O 1 ATOM 3490 C CB . THR C 2 32 ? 94.860 -5.034 34.939 1.00 58.19 ? 21 THR H CB 1 ATOM 3491 O OG1 . THR C 2 32 ? 94.516 -5.540 36.231 1.00 57.36 ? 21 THR H OG1 1 ATOM 3492 C CG2 . THR C 2 32 ? 94.485 -3.568 34.865 1.00 58.58 ? 21 THR H CG2 1 ATOM 3493 N N . CYS C 2 33 ? 93.947 -4.371 31.925 1.00 60.11 ? 22 CYS H N 1 ATOM 3494 C CA . CYS C 2 33 ? 94.306 -3.870 30.602 1.00 59.26 ? 22 CYS H CA 1 ATOM 3495 C C . CYS C 2 33 ? 94.595 -2.384 30.650 1.00 59.62 ? 22 CYS H C 1 ATOM 3496 O O . CYS C 2 33 ? 93.799 -1.605 31.163 1.00 58.95 ? 22 CYS H O 1 ATOM 3497 C CB . CYS C 2 33 ? 93.156 -4.148 29.640 1.00 57.64 ? 22 CYS H CB 1 ATOM 3498 S SG . CYS C 2 33 ? 93.306 -3.651 27.893 1.00 55.72 ? 22 CYS H SG 1 ATOM 3499 N N . THR C 2 34 ? 95.745 -1.994 30.119 1.00 60.62 ? 23 THR H N 1 ATOM 3500 C CA . THR C 2 34 ? 96.115 -0.593 30.106 1.00 60.89 ? 23 THR H CA 1 ATOM 3501 C C . THR C 2 34 ? 96.042 -0.078 28.687 1.00 62.04 ? 23 THR H C 1 ATOM 3502 O O . THR C 2 34 ? 96.524 -0.716 27.754 1.00 62.41 ? 23 THR H O 1 ATOM 3503 C CB . THR C 2 34 ? 97.528 -0.383 30.660 1.00 60.12 ? 23 THR H CB 1 ATOM 3504 O OG1 . THR C 2 34 ? 97.540 -0.712 32.056 1.00 58.81 ? 23 THR H OG1 1 ATOM 3505 C CG2 . THR C 2 34 ? 97.968 1.066 30.472 1.00 58.67 ? 23 THR H CG2 1 ATOM 3506 N N . VAL C 2 35 ? 95.415 1.076 28.527 1.00 62.54 ? 24 VAL H N 1 ATOM 3507 C CA . VAL C 2 35 ? 95.274 1.663 27.215 1.00 63.95 ? 24 VAL H CA 1 ATOM 3508 C C . VAL C 2 35 ? 96.227 2.841 27.074 1.00 65.64 ? 24 VAL H C 1 ATOM 3509 O O . VAL C 2 35 ? 96.436 3.607 28.017 1.00 66.62 ? 24 VAL H O 1 ATOM 3510 C CB . VAL C 2 35 ? 93.823 2.145 26.984 1.00 63.77 ? 24 VAL H CB 1 ATOM 3511 C CG1 . VAL C 2 35 ? 93.664 2.663 25.556 1.00 62.63 ? 24 VAL H CG1 1 ATOM 3512 C CG2 . VAL C 2 35 ? 92.847 1.007 27.269 1.00 62.54 ? 24 VAL H CG2 1 ATOM 3513 N N . SER C 2 36 ? 96.805 2.977 25.890 1.00 66.16 ? 25 SER H N 1 ATOM 3514 C CA . SER C 2 36 ? 97.729 4.064 25.613 1.00 66.56 ? 25 SER H CA 1 ATOM 3515 C C . SER C 2 36 ? 97.405 4.617 24.235 1.00 66.44 ? 25 SER H C 1 ATOM 3516 O O . SER C 2 36 ? 97.127 3.851 23.310 1.00 67.16 ? 25 SER H O 1 ATOM 3517 C CB . SER C 2 36 ? 99.163 3.539 25.653 1.00 67.91 ? 25 SER H CB 1 ATOM 3518 O OG . SER C 2 36 ? 99.266 2.300 24.964 1.00 70.39 ? 25 SER H OG 1 ATOM 3519 N N . GLY C 2 37 ? 97.432 5.941 24.103 1.00 65.43 ? 26 GLY H N 1 ATOM 3520 C CA . GLY C 2 37 ? 97.135 6.565 22.825 1.00 64.11 ? 26 GLY H CA 1 ATOM 3521 C C . GLY C 2 37 ? 95.648 6.543 22.531 1.00 63.70 ? 26 GLY H C 1 ATOM 3522 O O . GLY C 2 37 ? 95.222 6.431 21.379 1.00 64.37 ? 26 GLY H O 1 ATOM 3523 N N . GLY C 2 38 ? 94.865 6.649 23.599 1.00 62.56 ? 27 GLY H N 1 ATOM 3524 C CA . GLY C 2 38 ? 93.417 6.643 23.510 1.00 60.12 ? 27 GLY H CA 1 ATOM 3525 C C . GLY C 2 38 ? 92.885 6.643 24.931 1.00 59.58 ? 27 GLY H C 1 ATOM 3526 O O . GLY C 2 38 ? 93.341 5.854 25.767 1.00 60.39 ? 27 GLY H O 1 ATOM 3527 N N . SER C 2 39 ? 91.929 7.516 25.225 1.00 57.38 ? 28 SER H N 1 ATOM 3528 C CA . SER C 2 39 ? 91.396 7.579 26.574 1.00 56.70 ? 28 SER H CA 1 ATOM 3529 C C . SER C 2 39 ? 90.006 6.986 26.720 1.00 55.05 ? 28 SER H C 1 ATOM 3530 O O . SER C 2 39 ? 89.031 7.571 26.277 1.00 54.51 ? 28 SER H O 1 ATOM 3531 C CB . SER C 2 39 ? 91.387 9.026 27.066 1.00 58.09 ? 28 SER H CB 1 ATOM 3532 O OG . SER C 2 39 ? 90.868 9.100 28.386 1.00 61.59 ? 28 SER H OG 1 ATOM 3533 N N . ILE C 2 40 ? 89.920 5.826 27.359 1.00 54.16 ? 29 ILE H N 1 ATOM 3534 C CA . ILE C 2 40 ? 88.640 5.172 27.571 1.00 53.70 ? 29 ILE H CA 1 ATOM 3535 C C . ILE C 2 40 ? 87.609 6.199 28.006 1.00 54.69 ? 29 ILE H C 1 ATOM 3536 O O . ILE C 2 40 ? 86.421 6.060 27.736 1.00 57.02 ? 29 ILE H O 1 ATOM 3537 C CB . ILE C 2 40 ? 88.732 4.102 28.670 1.00 52.10 ? 29 ILE H CB 1 ATOM 3538 C CG1 . ILE C 2 40 ? 89.703 3.007 28.247 1.00 52.11 ? 29 ILE H CG1 1 ATOM 3539 C CG2 . ILE C 2 40 ? 87.357 3.502 28.935 1.00 51.47 ? 29 ILE H CG2 1 ATOM 3540 C CD1 . ILE C 2 40 ? 89.825 1.888 29.253 1.00 52.83 ? 29 ILE H CD1 1 ATOM 3541 N N . SER C 2 41 ? 88.074 7.239 28.679 1.00 55.17 ? 30 SER H N 1 ATOM 3542 C CA . SER C 2 41 ? 87.192 8.285 29.168 1.00 55.65 ? 30 SER H CA 1 ATOM 3543 C C . SER C 2 41 ? 86.462 9.076 28.063 1.00 55.41 ? 30 SER H C 1 ATOM 3544 O O . SER C 2 41 ? 85.486 9.783 28.350 1.00 55.92 ? 30 SER H O 1 ATOM 3545 C CB . SER C 2 41 ? 87.996 9.240 30.058 1.00 56.49 ? 30 SER H CB 1 ATOM 3546 O OG . SER C 2 41 ? 87.149 10.104 30.797 1.00 57.66 ? 30 SER H OG 1 ATOM 3547 N N . ARG C 2 42 ? 86.920 8.969 26.814 1.00 53.58 ? 31 ARG H N 1 ATOM 3548 C CA . ARG C 2 42 ? 86.283 9.693 25.706 1.00 52.22 ? 31 ARG H CA 1 ATOM 3549 C C . ARG C 2 42 ? 84.815 9.301 25.571 1.00 51.98 ? 31 ARG H C 1 ATOM 3550 O O . ARG C 2 42 ? 83.974 10.107 25.166 1.00 50.94 ? 31 ARG H O 1 ATOM 3551 C CB . ARG C 2 42 ? 87.029 9.432 24.390 1.00 51.88 ? 31 ARG H CB 1 ATOM 3552 C CG . ARG C 2 42 ? 86.249 9.827 23.130 1.00 52.49 ? 31 ARG H CG 1 ATOM 3553 C CD . ARG C 2 42 ? 87.150 10.055 21.920 1.00 49.60 ? 31 ARG H CD 1 ATOM 3554 N NE . ARG C 2 42 ? 87.821 11.349 22.010 1.00 49.36 ? 31 ARG H NE 1 ATOM 3555 C CZ . ARG C 2 42 ? 87.482 12.413 21.291 1.00 49.34 ? 31 ARG H CZ 1 ATOM 3556 N NH1 . ARG C 2 42 ? 88.139 13.552 21.445 1.00 48.63 ? 31 ARG H NH1 1 ATOM 3557 N NH2 . ARG C 2 42 ? 86.497 12.333 20.403 1.00 50.65 ? 31 ARG H NH2 1 ATOM 3558 N N . GLY C 2 43 ? 84.518 8.050 25.906 1.00 51.51 ? 32 GLY H N 1 ATOM 3559 C CA . GLY C 2 43 ? 83.150 7.568 25.862 1.00 50.81 ? 32 GLY H CA 1 ATOM 3560 C C . GLY C 2 43 ? 82.512 7.427 24.503 1.00 49.58 ? 32 GLY H C 1 ATOM 3561 O O . GLY C 2 43 ? 81.364 7.821 24.312 1.00 51.01 ? 32 GLY H O 1 ATOM 3562 N N . SER C 2 44 ? 83.242 6.850 23.560 1.00 46.89 ? 33 SER H N 1 ATOM 3563 C CA . SER C 2 44 ? 82.713 6.662 22.225 1.00 44.34 ? 33 SER H CA 1 ATOM 3564 C C . SER C 2 44 ? 82.864 5.196 21.837 1.00 43.32 ? 33 SER H C 1 ATOM 3565 O O . SER C 2 44 ? 82.476 4.789 20.741 1.00 44.02 ? 33 SER H O 1 ATOM 3566 C CB . SER C 2 44 ? 83.490 7.520 21.246 1.00 43.88 ? 33 SER H CB 1 ATOM 3567 O OG . SER C 2 44 ? 84.824 7.055 21.168 1.00 43.68 ? 33 SER H OG 1 ATOM 3568 N N . HIS C 2 45 ? 83.424 4.403 22.741 1.00 39.86 ? 34 HIS H N 1 ATOM 3569 C CA . HIS C 2 45 ? 83.649 2.999 22.461 1.00 37.60 ? 34 HIS H CA 1 ATOM 3570 C C . HIS C 2 45 ? 83.538 2.159 23.700 1.00 38.55 ? 34 HIS H C 1 ATOM 3571 O O . HIS C 2 45 ? 83.674 2.656 24.811 1.00 39.30 ? 34 HIS H O 1 ATOM 3572 C CB . HIS C 2 45 ? 85.049 2.792 21.901 1.00 35.89 ? 34 HIS H CB 1 ATOM 3573 C CG . HIS C 2 45 ? 85.246 3.352 20.532 1.00 34.48 ? 34 HIS H CG 1 ATOM 3574 N ND1 . HIS C 2 45 ? 85.260 2.563 19.405 1.00 33.09 ? 34 HIS H ND1 1 ATOM 3575 C CD2 . HIS C 2 45 ? 85.424 4.624 20.106 1.00 33.04 ? 34 HIS H CD2 1 ATOM 3576 C CE1 . HIS C 2 45 ? 85.437 3.324 18.341 1.00 32.65 ? 34 HIS H CE1 1 ATOM 3577 N NE2 . HIS C 2 45 ? 85.538 4.579 18.739 1.00 34.10 ? 34 HIS H NE2 1 ATOM 3578 N N . TYR C 2 46 ? 83.305 0.870 23.490 1.00 39.45 ? 35 TYR H N 1 ATOM 3579 C CA . TYR C 2 46 ? 83.218 -0.085 24.570 1.00 40.03 ? 35 TYR H CA 1 ATOM 3580 C C . TYR C 2 46 ? 84.512 -0.872 24.522 1.00 40.85 ? 35 TYR H C 1 ATOM 3581 O O . TYR C 2 46 ? 85.149 -0.971 23.472 1.00 39.67 ? 35 TYR H O 1 ATOM 3582 C CB . TYR C 2 46 ? 82.045 -1.028 24.367 1.00 40.67 ? 35 TYR H CB 1 ATOM 3583 C CG . TYR C 2 46 ? 80.698 -0.389 24.553 1.00 41.63 ? 35 TYR H CG 1 ATOM 3584 C CD1 . TYR C 2 46 ? 79.911 -0.699 25.654 1.00 41.33 ? 35 TYR H CD1 1 ATOM 3585 C CD2 . TYR C 2 46 ? 80.176 0.472 23.590 1.00 42.79 ? 35 TYR H CD2 1 ATOM 3586 C CE1 . TYR C 2 46 ? 78.629 -0.181 25.789 1.00 41.69 ? 35 TYR H CE1 1 ATOM 3587 C CE2 . TYR C 2 46 ? 78.892 0.999 23.713 1.00 42.36 ? 35 TYR H CE2 1 ATOM 3588 C CZ . TYR C 2 46 ? 78.122 0.662 24.814 1.00 42.15 ? 35 TYR H CZ 1 ATOM 3589 O OH . TYR C 2 46 ? 76.833 1.139 24.920 1.00 42.69 ? 35 TYR H OH 1 ATOM 3590 N N . TRP C 2 47 A 84.887 -1.437 25.664 1.00 41.85 ? 35 TRP H N 1 ATOM 3591 C CA . TRP C 2 47 A 86.115 -2.207 25.785 1.00 41.33 ? 35 TRP H CA 1 ATOM 3592 C C . TRP C 2 47 A 85.791 -3.562 26.376 1.00 41.63 ? 35 TRP H C 1 ATOM 3593 O O . TRP C 2 47 A 84.969 -3.658 27.282 1.00 41.92 ? 35 TRP H O 1 ATOM 3594 C CB . TRP C 2 47 A 87.081 -1.448 26.677 1.00 39.43 ? 35 TRP H CB 1 ATOM 3595 C CG . TRP C 2 47 A 87.205 -0.044 26.255 1.00 38.07 ? 35 TRP H CG 1 ATOM 3596 C CD1 . TRP C 2 47 A 86.292 0.951 26.441 1.00 38.03 ? 35 TRP H CD1 1 ATOM 3597 C CD2 . TRP C 2 47 A 88.270 0.523 25.498 1.00 38.79 ? 35 TRP H CD2 1 ATOM 3598 N NE1 . TRP C 2 47 A 86.721 2.107 25.840 1.00 38.72 ? 35 TRP H NE1 1 ATOM 3599 C CE2 . TRP C 2 47 A 87.935 1.871 25.252 1.00 38.84 ? 35 TRP H CE2 1 ATOM 3600 C CE3 . TRP C 2 47 A 89.476 0.023 24.998 1.00 39.60 ? 35 TRP H CE3 1 ATOM 3601 C CZ2 . TRP C 2 47 A 88.767 2.726 24.526 1.00 38.26 ? 35 TRP H CZ2 1 ATOM 3602 C CZ3 . TRP C 2 47 A 90.303 0.879 24.274 1.00 39.63 ? 35 TRP H CZ3 1 ATOM 3603 C CH2 . TRP C 2 47 A 89.942 2.214 24.047 1.00 36.84 ? 35 TRP H CH2 1 ATOM 3604 N N . GLY C 2 48 B 86.435 -4.608 25.874 1.00 41.90 ? 35 GLY H N 1 ATOM 3605 C CA . GLY C 2 48 B 86.136 -5.931 26.380 1.00 45.28 ? 35 GLY H CA 1 ATOM 3606 C C . GLY C 2 48 B 87.280 -6.916 26.422 1.00 47.81 ? 35 GLY H C 1 ATOM 3607 O O . GLY C 2 48 B 88.425 -6.575 26.126 1.00 49.08 ? 35 GLY H O 1 ATOM 3608 N N . TRP C 2 49 ? 86.950 -8.151 26.785 1.00 49.63 ? 36 TRP H N 1 ATOM 3609 C CA . TRP C 2 49 ? 87.922 -9.225 26.901 1.00 52.68 ? 36 TRP H CA 1 ATOM 3610 C C . TRP C 2 49 ? 87.531 -10.435 26.082 1.00 54.84 ? 36 TRP H C 1 ATOM 3611 O O . TRP C 2 49 ? 86.372 -10.842 26.093 1.00 56.71 ? 36 TRP H O 1 ATOM 3612 C CB . TRP C 2 49 ? 88.035 -9.686 28.353 1.00 55.01 ? 36 TRP H CB 1 ATOM 3613 C CG . TRP C 2 49 ? 88.560 -8.670 29.303 1.00 55.33 ? 36 TRP H CG 1 ATOM 3614 C CD1 . TRP C 2 49 ? 87.836 -7.779 30.033 1.00 54.91 ? 36 TRP H CD1 1 ATOM 3615 C CD2 . TRP C 2 49 ? 89.934 -8.422 29.606 1.00 56.11 ? 36 TRP H CD2 1 ATOM 3616 N NE1 . TRP C 2 49 ? 88.672 -6.985 30.773 1.00 56.45 ? 36 TRP H NE1 1 ATOM 3617 C CE2 . TRP C 2 49 ? 89.969 -7.357 30.531 1.00 57.85 ? 36 TRP H CE2 1 ATOM 3618 C CE3 . TRP C 2 49 ? 91.142 -8.996 29.185 1.00 56.23 ? 36 TRP H CE3 1 ATOM 3619 C CZ2 . TRP C 2 49 ? 91.175 -6.847 31.046 1.00 58.87 ? 36 TRP H CZ2 1 ATOM 3620 C CZ3 . TRP C 2 49 ? 92.339 -8.492 29.694 1.00 57.63 ? 36 TRP H CZ3 1 ATOM 3621 C CH2 . TRP C 2 49 ? 92.345 -7.427 30.615 1.00 57.82 ? 36 TRP H CH2 1 ATOM 3622 N N . ILE C 2 50 ? 88.500 -11.030 25.397 1.00 56.33 ? 37 ILE H N 1 ATOM 3623 C CA . ILE C 2 50 ? 88.233 -12.226 24.601 1.00 58.84 ? 37 ILE H CA 1 ATOM 3624 C C . ILE C 2 50 ? 89.285 -13.270 24.936 1.00 60.23 ? 37 ILE H C 1 ATOM 3625 O O . ILE C 2 50 ? 90.475 -12.953 24.961 1.00 61.06 ? 37 ILE H O 1 ATOM 3626 C CB . ILE C 2 50 ? 88.342 -11.969 23.080 1.00 58.66 ? 37 ILE H CB 1 ATOM 3627 C CG1 . ILE C 2 50 ? 87.551 -10.729 22.677 1.00 58.21 ? 37 ILE H CG1 1 ATOM 3628 C CG2 . ILE C 2 50 ? 87.850 -13.188 22.326 1.00 59.04 ? 37 ILE H CG2 1 ATOM 3629 C CD1 . ILE C 2 50 ? 88.251 -9.442 23.021 1.00 59.47 ? 37 ILE H CD1 1 ATOM 3630 N N . ARG C 2 51 ? 88.866 -14.506 25.188 1.00 60.74 ? 38 ARG H N 1 ATOM 3631 C CA . ARG C 2 51 ? 89.829 -15.562 25.490 1.00 61.28 ? 38 ARG H CA 1 ATOM 3632 C C . ARG C 2 51 ? 89.806 -16.631 24.416 1.00 62.35 ? 38 ARG H C 1 ATOM 3633 O O . ARG C 2 51 ? 88.836 -16.760 23.679 1.00 63.49 ? 38 ARG H O 1 ATOM 3634 C CB . ARG C 2 51 ? 89.542 -16.204 26.841 1.00 60.06 ? 38 ARG H CB 1 ATOM 3635 C CG . ARG C 2 51 ? 88.362 -17.130 26.835 1.00 60.29 ? 38 ARG H CG 1 ATOM 3636 C CD . ARG C 2 51 ? 88.241 -17.812 28.166 1.00 59.93 ? 38 ARG H CD 1 ATOM 3637 N NE . ARG C 2 51 ? 87.021 -18.599 28.241 1.00 61.42 ? 38 ARG H NE 1 ATOM 3638 C CZ . ARG C 2 51 ? 86.627 -19.241 29.333 1.00 62.81 ? 38 ARG H CZ 1 ATOM 3639 N NH1 . ARG C 2 51 ? 87.369 -19.183 30.433 1.00 62.96 ? 38 ARG H NH1 1 ATOM 3640 N NH2 . ARG C 2 51 ? 85.488 -19.922 29.330 1.00 62.23 ? 38 ARG H NH2 1 ATOM 3641 N N . GLN C 2 52 ? 90.876 -17.411 24.343 1.00 64.93 ? 39 GLN H N 1 ATOM 3642 C CA . GLN C 2 52 ? 90.990 -18.457 23.338 1.00 66.78 ? 39 GLN H CA 1 ATOM 3643 C C . GLN C 2 52 ? 91.854 -19.625 23.794 1.00 69.10 ? 39 GLN H C 1 ATOM 3644 O O . GLN C 2 52 ? 93.085 -19.535 23.783 1.00 70.50 ? 39 GLN H O 1 ATOM 3645 C CB . GLN C 2 52 ? 91.582 -17.862 22.056 1.00 65.91 ? 39 GLN H CB 1 ATOM 3646 C CG . GLN C 2 52 ? 92.106 -18.887 21.063 1.00 65.31 ? 39 GLN H CG 1 ATOM 3647 C CD . GLN C 2 52 ? 92.764 -18.245 19.854 1.00 65.39 ? 39 GLN H CD 1 ATOM 3648 O OE1 . GLN C 2 52 ? 93.642 -17.388 19.991 1.00 64.13 ? 39 GLN H OE1 1 ATOM 3649 N NE2 . GLN C 2 52 ? 92.350 -18.663 18.662 1.00 64.24 ? 39 GLN H NE2 1 ATOM 3650 N N . PRO C 2 53 ? 91.225 -20.735 24.217 1.00 71.00 ? 40 PRO H N 1 ATOM 3651 C CA . PRO C 2 53 ? 91.985 -21.911 24.664 1.00 72.68 ? 40 PRO H CA 1 ATOM 3652 C C . PRO C 2 53 ? 92.961 -22.323 23.566 1.00 74.47 ? 40 PRO H C 1 ATOM 3653 O O . PRO C 2 53 ? 92.564 -22.503 22.415 1.00 74.52 ? 40 PRO H O 1 ATOM 3654 C CB . PRO C 2 53 ? 90.901 -22.955 24.887 1.00 72.64 ? 40 PRO H CB 1 ATOM 3655 C CG . PRO C 2 53 ? 89.745 -22.120 25.364 1.00 72.50 ? 40 PRO H CG 1 ATOM 3656 C CD . PRO C 2 53 ? 89.778 -20.944 24.404 1.00 71.91 ? 40 PRO H CD 1 ATOM 3657 N N . PRO C 2 54 ? 94.250 -22.477 23.909 1.00 76.14 ? 41 PRO H N 1 ATOM 3658 C CA . PRO C 2 54 ? 95.298 -22.864 22.956 1.00 76.42 ? 41 PRO H CA 1 ATOM 3659 C C . PRO C 2 54 ? 94.800 -23.637 21.727 1.00 76.54 ? 41 PRO H C 1 ATOM 3660 O O . PRO C 2 54 ? 95.019 -23.228 20.583 1.00 76.14 ? 41 PRO H O 1 ATOM 3661 C CB . PRO C 2 54 ? 96.242 -23.686 23.822 1.00 76.43 ? 41 PRO H CB 1 ATOM 3662 C CG . PRO C 2 54 ? 96.211 -22.932 25.110 1.00 76.79 ? 41 PRO H CG 1 ATOM 3663 C CD . PRO C 2 54 ? 94.734 -22.611 25.297 1.00 76.38 ? 41 PRO H CD 1 ATOM 3664 N N . GLY C 2 55 ? 94.121 -24.751 21.971 1.00 76.61 ? 42 GLY H N 1 ATOM 3665 C CA . GLY C 2 55 ? 93.618 -25.549 20.870 1.00 76.61 ? 42 GLY H CA 1 ATOM 3666 C C . GLY C 2 55 ? 92.522 -24.878 20.068 1.00 75.96 ? 42 GLY H C 1 ATOM 3667 O O . GLY C 2 55 ? 92.753 -24.417 18.953 1.00 76.55 ? 42 GLY H O 1 ATOM 3668 N N . LYS C 2 56 ? 91.332 -24.807 20.656 1.00 74.82 ? 43 LYS H N 1 ATOM 3669 C CA . LYS C 2 56 ? 90.157 -24.226 20.012 1.00 72.80 ? 43 LYS H CA 1 ATOM 3670 C C . LYS C 2 56 ? 90.287 -22.775 19.534 1.00 71.70 ? 43 LYS H C 1 ATOM 3671 O O . LYS C 2 56 ? 91.395 -22.225 19.416 1.00 71.72 ? 43 LYS H O 1 ATOM 3672 C CB . LYS C 2 56 ? 88.963 -24.352 20.957 1.00 72.96 ? 43 LYS H CB 1 ATOM 3673 C CG . LYS C 2 56 ? 89.042 -25.581 21.849 1.00 73.51 ? 43 LYS H CG 1 ATOM 3674 C CD . LYS C 2 56 ? 89.318 -26.839 21.035 1.00 75.19 ? 43 LYS H CD 1 ATOM 3675 C CE . LYS C 2 56 ? 89.495 -28.049 21.941 1.00 76.20 ? 43 LYS H CE 1 ATOM 3676 N NZ . LYS C 2 56 ? 89.759 -29.305 21.165 1.00 75.82 ? 43 LYS H NZ 1 ATOM 3677 N N . GLY C 2 57 ? 89.133 -22.161 19.273 1.00 69.77 ? 44 GLY H N 1 ATOM 3678 C CA . GLY C 2 57 ? 89.092 -20.791 18.792 1.00 66.27 ? 44 GLY H CA 1 ATOM 3679 C C . GLY C 2 57 ? 88.752 -19.715 19.813 1.00 64.25 ? 44 GLY H C 1 ATOM 3680 O O . GLY C 2 57 ? 88.865 -19.914 21.028 1.00 64.02 ? 44 GLY H O 1 ATOM 3681 N N . LEU C 2 58 ? 88.303 -18.574 19.299 1.00 61.34 ? 45 LEU H N 1 ATOM 3682 C CA . LEU C 2 58 ? 87.966 -17.408 20.111 1.00 57.82 ? 45 LEU H CA 1 ATOM 3683 C C . LEU C 2 58 ? 86.642 -17.438 20.869 1.00 56.46 ? 45 LEU H C 1 ATOM 3684 O O . LEU C 2 58 ? 85.680 -18.072 20.439 1.00 56.38 ? 45 LEU H O 1 ATOM 3685 C CB . LEU C 2 58 ? 87.986 -16.170 19.223 1.00 56.18 ? 45 LEU H CB 1 ATOM 3686 C CG . LEU C 2 58 ? 89.303 -15.956 18.484 1.00 56.31 ? 45 LEU H CG 1 ATOM 3687 C CD1 . LEU C 2 58 ? 89.163 -14.829 17.484 1.00 55.93 ? 45 LEU H CD1 1 ATOM 3688 C CD2 . LEU C 2 58 ? 90.391 -15.638 19.494 1.00 57.82 ? 45 LEU H CD2 1 ATOM 3689 N N . GLU C 2 59 ? 86.609 -16.749 22.009 1.00 53.82 ? 46 GLU H N 1 ATOM 3690 C CA . GLU C 2 59 ? 85.395 -16.638 22.805 1.00 51.92 ? 46 GLU H CA 1 ATOM 3691 C C . GLU C 2 59 ? 85.288 -15.280 23.495 1.00 51.05 ? 46 GLU H C 1 ATOM 3692 O O . GLU C 2 59 ? 86.212 -14.843 24.191 1.00 50.07 ? 46 GLU H O 1 ATOM 3693 C CB . GLU C 2 59 ? 85.290 -17.732 23.860 1.00 52.52 ? 46 GLU H CB 1 ATOM 3694 C CG . GLU C 2 59 ? 84.129 -17.448 24.815 1.00 56.47 ? 46 GLU H CG 1 ATOM 3695 C CD . GLU C 2 59 ? 83.775 -18.598 25.741 1.00 57.78 ? 46 GLU H CD 1 ATOM 3696 O OE1 . GLU C 2 59 ? 84.649 -19.055 26.517 1.00 57.41 ? 46 GLU H OE1 1 ATOM 3697 O OE2 . GLU C 2 59 ? 82.601 -19.030 25.694 1.00 59.37 ? 46 GLU H OE2 1 ATOM 3698 N N . TRP C 2 60 ? 84.148 -14.618 23.293 1.00 49.71 ? 47 TRP H N 1 ATOM 3699 C CA . TRP C 2 60 ? 83.891 -13.309 23.888 1.00 47.42 ? 47 TRP H CA 1 ATOM 3700 C C . TRP C 2 60 ? 83.461 -13.499 25.337 1.00 46.38 ? 47 TRP H C 1 ATOM 3701 O O . TRP C 2 60 ? 82.732 -14.436 25.656 1.00 45.19 ? 47 TRP H O 1 ATOM 3702 C CB . TRP C 2 60 ? 82.798 -12.576 23.105 1.00 46.01 ? 47 TRP H CB 1 ATOM 3703 C CG . TRP C 2 60 ? 82.313 -11.308 23.748 1.00 42.51 ? 47 TRP H CG 1 ATOM 3704 C CD1 . TRP C 2 60 ? 83.023 -10.161 23.947 1.00 43.58 ? 47 TRP H CD1 1 ATOM 3705 C CD2 . TRP C 2 60 ? 81.018 -11.079 24.309 1.00 40.81 ? 47 TRP H CD2 1 ATOM 3706 N NE1 . TRP C 2 60 ? 82.250 -9.228 24.605 1.00 40.80 ? 47 TRP H NE1 1 ATOM 3707 C CE2 . TRP C 2 60 ? 81.015 -9.766 24.837 1.00 40.30 ? 47 TRP H CE2 1 ATOM 3708 C CE3 . TRP C 2 60 ? 79.857 -11.857 24.421 1.00 39.52 ? 47 TRP H CE3 1 ATOM 3709 C CZ2 . TRP C 2 60 ? 79.903 -9.216 25.464 1.00 38.96 ? 47 TRP H CZ2 1 ATOM 3710 C CZ3 . TRP C 2 60 ? 78.751 -11.310 25.047 1.00 38.04 ? 47 TRP H CZ3 1 ATOM 3711 C CH2 . TRP C 2 60 ? 78.782 -10.001 25.560 1.00 39.50 ? 47 TRP H CH2 1 ATOM 3712 N N . ILE C 2 61 ? 83.930 -12.611 26.208 1.00 45.80 ? 48 ILE H N 1 ATOM 3713 C CA . ILE C 2 61 ? 83.616 -12.674 27.629 1.00 44.68 ? 48 ILE H CA 1 ATOM 3714 C C . ILE C 2 61 ? 82.707 -11.524 28.039 1.00 45.83 ? 48 ILE H C 1 ATOM 3715 O O . ILE C 2 61 ? 81.575 -11.748 28.484 1.00 45.89 ? 48 ILE H O 1 ATOM 3716 C CB . ILE C 2 61 ? 84.903 -12.622 28.480 1.00 43.26 ? 48 ILE H CB 1 ATOM 3717 C CG1 . ILE C 2 61 ? 85.760 -13.854 28.190 1.00 41.66 ? 48 ILE H CG1 1 ATOM 3718 C CG2 . ILE C 2 61 ? 84.554 -12.578 29.967 1.00 42.18 ? 48 ILE H CG2 1 ATOM 3719 C CD1 . ILE C 2 61 ? 87.218 -13.652 28.481 1.00 42.17 ? 48 ILE H CD1 1 ATOM 3720 N N . GLY C 2 62 ? 83.206 -10.298 27.883 1.00 44.70 ? 49 GLY H N 1 ATOM 3721 C CA . GLY C 2 62 ? 82.418 -9.136 28.249 1.00 43.85 ? 49 GLY H CA 1 ATOM 3722 C C . GLY C 2 62 ? 82.978 -7.806 27.781 1.00 43.81 ? 49 GLY H C 1 ATOM 3723 O O . GLY C 2 62 ? 84.155 -7.696 27.426 1.00 44.07 ? 49 GLY H O 1 ATOM 3724 N N . SER C 2 63 ? 82.121 -6.788 27.782 1.00 41.86 ? 50 SER H N 1 ATOM 3725 C CA . SER C 2 63 ? 82.507 -5.451 27.373 1.00 39.77 ? 50 SER H CA 1 ATOM 3726 C C . SER C 2 63 ? 82.007 -4.498 28.426 1.00 39.37 ? 50 SER H C 1 ATOM 3727 O O . SER C 2 63 ? 81.019 -4.776 29.091 1.00 39.79 ? 50 SER H O 1 ATOM 3728 C CB . SER C 2 63 ? 81.862 -5.094 26.048 1.00 41.50 ? 50 SER H CB 1 ATOM 3729 O OG . SER C 2 63 ? 82.107 -6.087 25.073 1.00 46.79 ? 50 SER H OG 1 ATOM 3730 N N . ILE C 2 64 ? 82.684 -3.368 28.571 1.00 39.25 ? 51 ILE H N 1 ATOM 3731 C CA . ILE C 2 64 ? 82.302 -2.359 29.554 1.00 38.88 ? 51 ILE H CA 1 ATOM 3732 C C . ILE C 2 64 ? 82.472 -0.959 28.973 1.00 38.69 ? 51 ILE H C 1 ATOM 3733 O O . ILE C 2 64 ? 83.356 -0.724 28.152 1.00 39.07 ? 51 ILE H O 1 ATOM 3734 C CB . ILE C 2 64 ? 83.167 -2.469 30.840 1.00 40.17 ? 51 ILE H CB 1 ATOM 3735 C CG1 . ILE C 2 64 ? 82.916 -1.257 31.737 1.00 38.11 ? 51 ILE H CG1 1 ATOM 3736 C CG2 . ILE C 2 64 ? 84.659 -2.560 30.474 1.00 40.53 ? 51 ILE H CG2 1 ATOM 3737 C CD1 . ILE C 2 64 ? 83.521 -1.378 33.090 1.00 36.27 ? 51 ILE H CD1 1 ATOM 3738 N N . TYR C 2 65 ? 81.615 -0.039 29.404 1.00 38.36 ? 52 TYR H N 1 ATOM 3739 C CA . TYR C 2 65 ? 81.652 1.355 28.946 1.00 37.41 ? 52 TYR H CA 1 ATOM 3740 C C . TYR C 2 65 ? 82.350 2.136 30.055 1.00 37.70 ? 52 TYR H C 1 ATOM 3741 O O . TYR C 2 65 ? 82.293 1.732 31.209 1.00 39.20 ? 52 TYR H O 1 ATOM 3742 C CB . TYR C 2 65 ? 80.215 1.860 28.730 1.00 34.09 ? 52 TYR H CB 1 ATOM 3743 C CG . TYR C 2 65 ? 80.080 3.199 28.033 1.00 30.27 ? 52 TYR H CG 1 ATOM 3744 C CD1 . TYR C 2 65 ? 79.738 4.346 28.742 1.00 28.69 ? 52 TYR H CD1 1 ATOM 3745 C CD2 . TYR C 2 65 ? 80.274 3.312 26.662 1.00 30.00 ? 52 TYR H CD2 1 ATOM 3746 C CE1 . TYR C 2 65 ? 79.587 5.577 28.102 1.00 28.64 ? 52 TYR H CE1 1 ATOM 3747 C CE2 . TYR C 2 65 ? 80.134 4.537 26.011 1.00 29.52 ? 52 TYR H CE2 1 ATOM 3748 C CZ . TYR C 2 65 ? 79.792 5.667 26.736 1.00 28.96 ? 52 TYR H CZ 1 ATOM 3749 O OH . TYR C 2 65 ? 79.692 6.884 26.097 1.00 26.79 ? 52 TYR H OH 1 ATOM 3750 N N . TYR C 2 66 ? 83.010 3.240 29.726 1.00 37.92 ? 53 TYR H N 1 ATOM 3751 C CA . TYR C 2 66 ? 83.703 4.000 30.756 1.00 38.97 ? 53 TYR H CA 1 ATOM 3752 C C . TYR C 2 66 ? 82.825 4.336 31.970 1.00 40.90 ? 53 TYR H C 1 ATOM 3753 O O . TYR C 2 66 ? 83.316 4.406 33.091 1.00 41.06 ? 53 TYR H O 1 ATOM 3754 C CB . TYR C 2 66 ? 84.303 5.288 30.170 1.00 37.31 ? 53 TYR H CB 1 ATOM 3755 C CG . TYR C 2 66 ? 83.369 6.482 30.113 1.00 36.55 ? 53 TYR H CG 1 ATOM 3756 C CD1 . TYR C 2 66 ? 82.753 6.857 28.925 1.00 35.87 ? 53 TYR H CD1 1 ATOM 3757 C CD2 . TYR C 2 66 ? 83.121 7.252 31.250 1.00 35.00 ? 53 TYR H CD2 1 ATOM 3758 C CE1 . TYR C 2 66 ? 81.912 7.978 28.870 1.00 35.79 ? 53 TYR H CE1 1 ATOM 3759 C CE2 . TYR C 2 66 ? 82.287 8.364 31.207 1.00 33.68 ? 53 TYR H CE2 1 ATOM 3760 C CZ . TYR C 2 66 ? 81.688 8.725 30.020 1.00 36.01 ? 53 TYR H CZ 1 ATOM 3761 O OH . TYR C 2 66 ? 80.871 9.836 29.980 1.00 36.90 ? 53 TYR H OH 1 ATOM 3762 N N . SER C 2 67 ? 81.528 4.526 31.758 1.00 43.53 ? 54 SER H N 1 ATOM 3763 C CA . SER C 2 67 ? 80.637 4.878 32.863 1.00 46.64 ? 54 SER H CA 1 ATOM 3764 C C . SER C 2 67 ? 80.250 3.710 33.750 1.00 48.82 ? 54 SER H C 1 ATOM 3765 O O . SER C 2 67 ? 79.496 3.898 34.704 1.00 50.57 ? 54 SER H O 1 ATOM 3766 C CB . SER C 2 67 ? 79.343 5.483 32.349 1.00 47.52 ? 54 SER H CB 1 ATOM 3767 O OG . SER C 2 67 ? 78.445 4.434 32.023 1.00 49.86 ? 54 SER H OG 1 ATOM 3768 N N . GLY C 2 68 ? 80.722 2.508 33.433 1.00 49.42 ? 55 GLY H N 1 ATOM 3769 C CA . GLY C 2 68 ? 80.380 1.364 34.259 1.00 50.85 ? 55 GLY H CA 1 ATOM 3770 C C . GLY C 2 68 ? 79.569 0.270 33.586 1.00 52.95 ? 55 GLY H C 1 ATOM 3771 O O . GLY C 2 68 ? 79.970 -0.888 33.612 1.00 53.19 ? 55 GLY H O 1 ATOM 3772 N N . ASN C 2 69 ? 78.424 0.630 33.007 1.00 55.28 ? 56 ASN H N 1 ATOM 3773 C CA . ASN C 2 69 ? 77.545 -0.319 32.314 1.00 55.39 ? 56 ASN H CA 1 ATOM 3774 C C . ASN C 2 69 ? 78.362 -1.376 31.531 1.00 54.03 ? 56 ASN H C 1 ATOM 3775 O O . ASN C 2 69 ? 79.165 -1.047 30.655 1.00 51.83 ? 56 ASN H O 1 ATOM 3776 C CB . ASN C 2 69 ? 76.605 0.480 31.386 1.00 59.09 ? 56 ASN H CB 1 ATOM 3777 C CG . ASN C 2 69 ? 75.805 -0.404 30.414 1.00 64.70 ? 56 ASN H CG 1 ATOM 3778 O OD1 . ASN C 2 69 ? 75.376 0.069 29.355 1.00 65.57 ? 56 ASN H OD1 1 ATOM 3779 N ND2 . ASN C 2 69 ? 75.592 -1.677 30.772 1.00 67.35 ? 56 ASN H ND2 1 ATOM 3780 N N . THR C 2 70 ? 78.153 -2.649 31.863 1.00 54.59 ? 57 THR H N 1 ATOM 3781 C CA . THR C 2 70 ? 78.876 -3.746 31.212 1.00 55.26 ? 57 THR H CA 1 ATOM 3782 C C . THR C 2 70 ? 77.961 -4.814 30.605 1.00 55.67 ? 57 THR H C 1 ATOM 3783 O O . THR C 2 70 ? 76.809 -4.961 31.012 1.00 56.88 ? 57 THR H O 1 ATOM 3784 C CB . THR C 2 70 ? 79.820 -4.455 32.207 1.00 54.80 ? 57 THR H CB 1 ATOM 3785 O OG1 . THR C 2 70 ? 79.049 -5.141 33.195 1.00 54.45 ? 57 THR H OG1 1 ATOM 3786 C CG2 . THR C 2 70 ? 80.705 -3.456 32.907 1.00 54.69 ? 57 THR H CG2 1 ATOM 3787 N N . TYR C 2 71 ? 78.486 -5.550 29.628 1.00 55.22 ? 58 TYR H N 1 ATOM 3788 C CA . TYR C 2 71 ? 77.742 -6.617 28.965 1.00 55.52 ? 58 TYR H CA 1 ATOM 3789 C C . TYR C 2 71 ? 78.550 -7.895 29.068 1.00 54.25 ? 58 TYR H C 1 ATOM 3790 O O . TYR C 2 71 ? 79.715 -7.926 28.687 1.00 54.45 ? 58 TYR H O 1 ATOM 3791 C CB . TYR C 2 71 ? 77.507 -6.280 27.496 1.00 59.15 ? 58 TYR H CB 1 ATOM 3792 C CG . TYR C 2 71 ? 76.657 -5.051 27.293 1.00 64.30 ? 58 TYR H CG 1 ATOM 3793 C CD1 . TYR C 2 71 ? 77.123 -3.796 27.672 1.00 66.22 ? 58 TYR H CD1 1 ATOM 3794 C CD2 . TYR C 2 71 ? 75.361 -5.148 26.776 1.00 66.18 ? 58 TYR H CD2 1 ATOM 3795 C CE1 . TYR C 2 71 ? 76.323 -2.666 27.555 1.00 69.15 ? 58 TYR H CE1 1 ATOM 3796 C CE2 . TYR C 2 71 ? 74.552 -4.022 26.652 1.00 68.79 ? 58 TYR H CE2 1 ATOM 3797 C CZ . TYR C 2 71 ? 75.042 -2.783 27.050 1.00 69.73 ? 58 TYR H CZ 1 ATOM 3798 O OH . TYR C 2 71 ? 74.252 -1.657 26.977 1.00 72.58 ? 58 TYR H OH 1 ATOM 3799 N N . PHE C 2 72 ? 77.925 -8.949 29.580 1.00 52.52 ? 59 PHE H N 1 ATOM 3800 C CA . PHE C 2 72 ? 78.604 -10.222 29.763 1.00 51.22 ? 59 PHE H CA 1 ATOM 3801 C C . PHE C 2 72 ? 78.146 -11.306 28.825 1.00 50.57 ? 59 PHE H C 1 ATOM 3802 O O . PHE C 2 72 ? 77.133 -11.169 28.145 1.00 51.56 ? 59 PHE H O 1 ATOM 3803 C CB . PHE C 2 72 ? 78.403 -10.716 31.188 1.00 52.01 ? 59 PHE H CB 1 ATOM 3804 C CG . PHE C 2 72 ? 78.923 -9.784 32.218 1.00 51.94 ? 59 PHE H CG 1 ATOM 3805 C CD1 . PHE C 2 72 ? 78.081 -9.258 33.174 1.00 52.32 ? 59 PHE H CD1 1 ATOM 3806 C CD2 . PHE C 2 72 ? 80.259 -9.420 32.224 1.00 53.91 ? 59 PHE H CD2 1 ATOM 3807 C CE1 . PHE C 2 72 ? 78.559 -8.378 34.129 1.00 55.75 ? 59 PHE H CE1 1 ATOM 3808 C CE2 . PHE C 2 72 ? 80.753 -8.538 33.175 1.00 56.31 ? 59 PHE H CE2 1 ATOM 3809 C CZ . PHE C 2 72 ? 79.901 -8.014 34.132 1.00 56.39 ? 59 PHE H CZ 1 ATOM 3810 N N . ASN C 2 73 ? 78.909 -12.391 28.792 1.00 50.06 ? 60 ASN H N 1 ATOM 3811 C CA . ASN C 2 73 ? 78.561 -13.526 27.961 1.00 50.11 ? 60 ASN H CA 1 ATOM 3812 C C . ASN C 2 73 ? 77.768 -14.502 28.848 1.00 52.14 ? 60 ASN H C 1 ATOM 3813 O O . ASN C 2 73 ? 78.302 -15.070 29.805 1.00 52.10 ? 60 ASN H O 1 ATOM 3814 C CB . ASN C 2 73 ? 79.817 -14.192 27.406 1.00 45.78 ? 60 ASN H CB 1 ATOM 3815 C CG . ASN C 2 73 ? 79.489 -15.335 26.487 1.00 43.94 ? 60 ASN H CG 1 ATOM 3816 O OD1 . ASN C 2 73 ? 78.510 -16.035 26.700 1.00 43.65 ? 60 ASN H OD1 1 ATOM 3817 N ND2 . ASN C 2 73 ? 80.307 -15.544 25.466 1.00 45.55 ? 60 ASN H ND2 1 ATOM 3818 N N . PRO C 2 74 ? 76.476 -14.702 28.539 1.00 54.33 ? 61 PRO H N 1 ATOM 3819 C CA . PRO C 2 74 ? 75.592 -15.595 29.295 1.00 57.22 ? 61 PRO H CA 1 ATOM 3820 C C . PRO C 2 74 ? 76.210 -16.941 29.669 1.00 59.82 ? 61 PRO H C 1 ATOM 3821 O O . PRO C 2 74 ? 75.889 -17.525 30.705 1.00 59.37 ? 61 PRO H O 1 ATOM 3822 C CB . PRO C 2 74 ? 74.389 -15.745 28.365 1.00 56.52 ? 61 PRO H CB 1 ATOM 3823 C CG . PRO C 2 74 ? 74.986 -15.537 27.004 1.00 54.60 ? 61 PRO H CG 1 ATOM 3824 C CD . PRO C 2 74 ? 75.855 -14.352 27.253 1.00 54.35 ? 61 PRO H CD 1 ATOM 3825 N N . SER C 2 75 ? 77.098 -17.427 28.814 1.00 62.89 ? 62 SER H N 1 ATOM 3826 C CA . SER C 2 75 ? 77.754 -18.698 29.053 1.00 65.14 ? 62 SER H CA 1 ATOM 3827 C C . SER C 2 75 ? 78.505 -18.682 30.381 1.00 67.07 ? 62 SER H C 1 ATOM 3828 O O . SER C 2 75 ? 78.655 -19.724 31.023 1.00 68.21 ? 62 SER H O 1 ATOM 3829 C CB . SER C 2 75 ? 78.748 -18.997 27.934 1.00 64.72 ? 62 SER H CB 1 ATOM 3830 O OG . SER C 2 75 ? 79.999 -18.384 28.205 1.00 65.42 ? 62 SER H OG 1 ATOM 3831 N N . LEU C 2 76 ? 78.958 -17.505 30.806 1.00 67.88 ? 63 LEU H N 1 ATOM 3832 C CA . LEU C 2 76 ? 79.730 -17.431 32.036 1.00 69.53 ? 63 LEU H CA 1 ATOM 3833 C C . LEU C 2 76 ? 79.672 -16.131 32.842 1.00 71.40 ? 63 LEU H C 1 ATOM 3834 O O . LEU C 2 76 ? 80.616 -15.811 33.565 1.00 71.78 ? 63 LEU H O 1 ATOM 3835 C CB . LEU C 2 76 ? 81.188 -17.772 31.703 1.00 68.62 ? 63 LEU H CB 1 ATOM 3836 C CG . LEU C 2 76 ? 81.837 -17.010 30.543 1.00 67.37 ? 63 LEU H CG 1 ATOM 3837 C CD1 . LEU C 2 76 ? 82.242 -15.634 31.005 1.00 67.01 ? 63 LEU H CD1 1 ATOM 3838 C CD2 . LEU C 2 76 ? 83.062 -17.749 30.053 1.00 67.64 ? 63 LEU H CD2 1 ATOM 3839 N N . LYS C 2 77 ? 78.571 -15.389 32.744 1.00 73.69 ? 64 LYS H N 1 ATOM 3840 C CA . LYS C 2 77 ? 78.447 -14.130 33.487 1.00 73.93 ? 64 LYS H CA 1 ATOM 3841 C C . LYS C 2 77 ? 78.427 -14.295 35.003 1.00 73.04 ? 64 LYS H C 1 ATOM 3842 O O . LYS C 2 77 ? 79.011 -13.490 35.736 1.00 72.57 ? 64 LYS H O 1 ATOM 3843 C CB . LYS C 2 77 ? 77.196 -13.358 33.046 1.00 76.01 ? 64 LYS H CB 1 ATOM 3844 C CG . LYS C 2 77 ? 75.913 -14.177 32.909 1.00 78.59 ? 64 LYS H CG 1 ATOM 3845 C CD . LYS C 2 77 ? 74.757 -13.286 32.405 1.00 80.41 ? 64 LYS H CD 1 ATOM 3846 C CE . LYS C 2 77 ? 73.616 -14.101 31.783 1.00 80.54 ? 64 LYS H CE 1 ATOM 3847 N NZ . LYS C 2 77 ? 73.006 -15.094 32.720 1.00 79.31 ? 64 LYS H NZ 1 ATOM 3848 N N . SER C 2 78 ? 77.753 -15.343 35.463 1.00 72.11 ? 65 SER H N 1 ATOM 3849 C CA . SER C 2 78 ? 77.629 -15.630 36.887 1.00 70.65 ? 65 SER H CA 1 ATOM 3850 C C . SER C 2 78 ? 78.960 -15.671 37.622 1.00 68.69 ? 65 SER H C 1 ATOM 3851 O O . SER C 2 78 ? 78.995 -15.519 38.845 1.00 69.11 ? 65 SER H O 1 ATOM 3852 C CB . SER C 2 78 ? 76.907 -16.959 37.089 1.00 71.53 ? 65 SER H CB 1 ATOM 3853 O OG . SER C 2 78 ? 77.626 -18.019 36.483 1.00 74.04 ? 65 SER H OG 1 ATOM 3854 N N . ARG C 2 79 ? 80.051 -15.866 36.885 1.00 66.02 ? 66 ARG H N 1 ATOM 3855 C CA . ARG C 2 79 ? 81.375 -15.939 37.499 1.00 63.07 ? 66 ARG H CA 1 ATOM 3856 C C . ARG C 2 79 ? 82.419 -14.974 36.939 1.00 60.66 ? 66 ARG H C 1 ATOM 3857 O O . ARG C 2 79 ? 83.619 -15.192 37.087 1.00 59.89 ? 66 ARG H O 1 ATOM 3858 C CB . ARG C 2 79 ? 81.898 -17.376 37.417 1.00 63.76 ? 66 ARG H CB 1 ATOM 3859 C CG . ARG C 2 79 ? 81.303 -18.216 36.277 1.00 64.26 ? 66 ARG H CG 1 ATOM 3860 C CD . ARG C 2 79 ? 81.783 -19.663 36.358 1.00 62.28 ? 66 ARG H CD 1 ATOM 3861 N NE . ARG C 2 79 ? 83.243 -19.728 36.313 1.00 62.93 ? 66 ARG H NE 1 ATOM 3862 C CZ . ARG C 2 79 ? 83.965 -19.701 35.196 1.00 62.11 ? 66 ARG H CZ 1 ATOM 3863 N NH1 . ARG C 2 79 ? 83.368 -19.622 34.010 1.00 60.82 ? 66 ARG H NH1 1 ATOM 3864 N NH2 . ARG C 2 79 ? 85.289 -19.732 35.271 1.00 60.92 ? 66 ARG H NH2 1 ATOM 3865 N N . VAL C 2 80 ? 81.966 -13.900 36.307 1.00 58.12 ? 67 VAL H N 1 ATOM 3866 C CA . VAL C 2 80 ? 82.890 -12.928 35.748 1.00 56.12 ? 67 VAL H CA 1 ATOM 3867 C C . VAL C 2 80 ? 82.634 -11.538 36.338 1.00 55.75 ? 67 VAL H C 1 ATOM 3868 O O . VAL C 2 80 ? 81.533 -11.236 36.806 1.00 57.50 ? 67 VAL H O 1 ATOM 3869 C CB . VAL C 2 80 ? 82.775 -12.894 34.217 1.00 54.48 ? 67 VAL H CB 1 ATOM 3870 C CG1 . VAL C 2 80 ? 81.336 -12.733 33.822 1.00 55.43 ? 67 VAL H CG1 1 ATOM 3871 C CG2 . VAL C 2 80 ? 83.609 -11.772 33.651 1.00 54.80 ? 67 VAL H CG2 1 ATOM 3872 N N . THR C 2 81 ? 83.662 -10.700 36.317 1.00 52.99 ? 68 THR H N 1 ATOM 3873 C CA . THR C 2 81 ? 83.585 -9.361 36.871 1.00 50.13 ? 68 THR H CA 1 ATOM 3874 C C . THR C 2 81 ? 84.457 -8.412 36.050 1.00 49.40 ? 68 THR H C 1 ATOM 3875 O O . THR C 2 81 ? 85.657 -8.630 35.897 1.00 50.64 ? 68 THR H O 1 ATOM 3876 C CB . THR C 2 81 ? 84.085 -9.375 38.334 1.00 51.11 ? 68 THR H CB 1 ATOM 3877 O OG1 . THR C 2 81 ? 83.130 -10.055 39.158 1.00 50.64 ? 68 THR H OG1 1 ATOM 3878 C CG2 . THR C 2 81 ? 84.319 -7.958 38.852 1.00 52.27 ? 68 THR H CG2 1 ATOM 3879 N N . ILE C 2 82 ? 83.862 -7.359 35.512 1.00 47.79 ? 69 ILE H N 1 ATOM 3880 C CA . ILE C 2 82 ? 84.635 -6.409 34.726 1.00 45.79 ? 69 ILE H CA 1 ATOM 3881 C C . ILE C 2 82 ? 84.498 -4.996 35.286 1.00 46.18 ? 69 ILE H C 1 ATOM 3882 O O . ILE C 2 82 ? 83.434 -4.609 35.773 1.00 44.98 ? 69 ILE H O 1 ATOM 3883 C CB . ILE C 2 82 ? 84.201 -6.411 33.249 1.00 43.81 ? 69 ILE H CB 1 ATOM 3884 C CG1 . ILE C 2 82 ? 84.207 -7.839 32.703 1.00 39.91 ? 69 ILE H CG1 1 ATOM 3885 C CG2 . ILE C 2 82 ? 85.142 -5.536 32.442 1.00 42.63 ? 69 ILE H CG2 1 ATOM 3886 C CD1 . ILE C 2 82 ? 83.920 -7.911 31.229 1.00 39.08 ? 69 ILE H CD1 1 ATOM 3887 N N . SER C 2 83 ? 85.582 -4.229 35.224 1.00 47.16 ? 70 SER H N 1 ATOM 3888 C CA . SER C 2 83 ? 85.556 -2.873 35.747 1.00 49.44 ? 70 SER H CA 1 ATOM 3889 C C . SER C 2 83 ? 86.590 -2.003 35.070 1.00 50.38 ? 70 SER H C 1 ATOM 3890 O O . SER C 2 83 ? 87.565 -2.508 34.506 1.00 49.63 ? 70 SER H O 1 ATOM 3891 C CB . SER C 2 83 ? 85.827 -2.875 37.250 1.00 49.57 ? 70 SER H CB 1 ATOM 3892 O OG . SER C 2 83 ? 85.010 -3.815 37.919 1.00 53.39 ? 70 SER H OG 1 ATOM 3893 N N . VAL C 2 84 ? 86.358 -0.693 35.137 1.00 51.34 ? 71 VAL H N 1 ATOM 3894 C CA . VAL C 2 84 ? 87.258 0.301 34.568 1.00 54.01 ? 71 VAL H CA 1 ATOM 3895 C C . VAL C 2 84 ? 87.647 1.338 35.607 1.00 56.28 ? 71 VAL H C 1 ATOM 3896 O O . VAL C 2 84 ? 86.910 1.603 36.561 1.00 56.38 ? 71 VAL H O 1 ATOM 3897 C CB . VAL C 2 84 ? 86.614 1.105 33.416 1.00 54.16 ? 71 VAL H CB 1 ATOM 3898 C CG1 . VAL C 2 84 ? 86.639 0.314 32.141 1.00 55.39 ? 71 VAL H CG1 1 ATOM 3899 C CG2 . VAL C 2 84 ? 85.196 1.498 33.790 1.00 52.00 ? 71 VAL H CG2 1 ATOM 3900 N N . ASP C 2 85 ? 88.817 1.926 35.412 1.00 57.46 ? 72 ASP H N 1 ATOM 3901 C CA . ASP C 2 85 ? 89.269 2.980 36.286 1.00 59.03 ? 72 ASP H CA 1 ATOM 3902 C C . ASP C 2 85 ? 89.739 4.042 35.329 1.00 58.79 ? 72 ASP H C 1 ATOM 3903 O O . ASP C 2 85 ? 90.764 3.885 34.669 1.00 58.57 ? 72 ASP H O 1 ATOM 3904 C CB . ASP C 2 85 ? 90.420 2.531 37.170 1.00 62.52 ? 72 ASP H CB 1 ATOM 3905 C CG . ASP C 2 85 ? 90.808 3.591 38.181 1.00 66.09 ? 72 ASP H CG 1 ATOM 3906 O OD1 . ASP C 2 85 ? 89.986 3.893 39.074 1.00 68.30 ? 72 ASP H OD1 1 ATOM 3907 O OD2 . ASP C 2 85 ? 91.928 4.134 38.077 1.00 69.53 ? 72 ASP H OD2 1 ATOM 3908 N N . THR C 2 86 ? 88.960 5.108 35.229 1.00 58.68 ? 73 THR H N 1 ATOM 3909 C CA . THR C 2 86 ? 89.281 6.205 34.335 1.00 58.89 ? 73 THR H CA 1 ATOM 3910 C C . THR C 2 86 ? 90.613 6.838 34.711 1.00 58.82 ? 73 THR H C 1 ATOM 3911 O O . THR C 2 86 ? 91.449 7.120 33.858 1.00 57.12 ? 73 THR H O 1 ATOM 3912 C CB . THR C 2 86 ? 88.195 7.274 34.403 1.00 59.29 ? 73 THR H CB 1 ATOM 3913 O OG1 . THR C 2 86 ? 86.923 6.671 34.151 1.00 59.26 ? 73 THR H OG1 1 ATOM 3914 C CG2 . THR C 2 86 ? 88.450 8.352 33.374 1.00 61.68 ? 73 THR H CG2 1 ATOM 3915 N N . SER C 2 87 ? 90.797 7.055 36.005 1.00 59.96 ? 74 SER H N 1 ATOM 3916 C CA . SER C 2 87 ? 92.010 7.661 36.523 1.00 60.95 ? 74 SER H CA 1 ATOM 3917 C C . SER C 2 87 ? 93.281 7.019 35.990 1.00 61.73 ? 74 SER H C 1 ATOM 3918 O O . SER C 2 87 ? 94.159 7.712 35.481 1.00 62.36 ? 74 SER H O 1 ATOM 3919 C CB . SER C 2 87 ? 91.993 7.608 38.050 1.00 61.34 ? 74 SER H CB 1 ATOM 3920 O OG . SER C 2 87 ? 91.250 6.491 38.513 1.00 61.07 ? 74 SER H OG 1 ATOM 3921 N N . LYS C 2 88 ? 93.381 5.700 36.102 1.00 61.98 ? 75 LYS H N 1 ATOM 3922 C CA . LYS C 2 88 ? 94.563 4.997 35.628 1.00 64.13 ? 75 LYS H CA 1 ATOM 3923 C C . LYS C 2 88 ? 94.419 4.578 34.172 1.00 64.42 ? 75 LYS H C 1 ATOM 3924 O O . LYS C 2 88 ? 95.337 3.977 33.604 1.00 64.80 ? 75 LYS H O 1 ATOM 3925 C CB . LYS C 2 88 ? 94.831 3.758 36.492 1.00 67.23 ? 75 LYS H CB 1 ATOM 3926 C CG . LYS C 2 88 ? 95.133 4.064 37.968 1.00 71.80 ? 75 LYS H CG 1 ATOM 3927 C CD . LYS C 2 88 ? 95.374 2.785 38.776 1.00 73.30 ? 75 LYS H CD 1 ATOM 3928 C CE . LYS C 2 88 ? 95.536 3.079 40.268 1.00 74.61 ? 75 LYS H CE 1 ATOM 3929 N NZ . LYS C 2 88 ? 95.722 1.830 41.078 1.00 75.05 ? 75 LYS H NZ 1 ATOM 3930 N N . ASN C 2 89 ? 93.268 4.905 33.579 1.00 63.26 ? 76 ASN H N 1 ATOM 3931 C CA . ASN C 2 89 ? 92.944 4.571 32.184 1.00 60.24 ? 76 ASN H CA 1 ATOM 3932 C C . ASN C 2 89 ? 93.127 3.092 31.852 1.00 58.43 ? 76 ASN H C 1 ATOM 3933 O O . ASN C 2 89 ? 93.930 2.715 30.999 1.00 56.77 ? 76 ASN H O 1 ATOM 3934 C CB . ASN C 2 89 ? 93.766 5.417 31.214 1.00 59.42 ? 76 ASN H CB 1 ATOM 3935 C CG . ASN C 2 89 ? 93.482 5.070 29.770 1.00 61.27 ? 76 ASN H CG 1 ATOM 3936 O OD1 . ASN C 2 89 ? 93.986 4.076 29.251 1.00 62.13 ? 76 ASN H OD1 1 ATOM 3937 N ND2 . ASN C 2 89 ? 92.652 5.877 29.116 1.00 61.51 ? 76 ASN H ND2 1 ATOM 3938 N N . GLN C 2 90 ? 92.355 2.249 32.519 1.00 56.76 ? 77 GLN H N 1 ATOM 3939 C CA . GLN C 2 90 ? 92.472 0.827 32.285 1.00 56.23 ? 77 GLN H CA 1 ATOM 3940 C C . GLN C 2 90 ? 91.239 0.082 32.795 1.00 54.36 ? 77 GLN H C 1 ATOM 3941 O O . GLN C 2 90 ? 90.525 0.569 33.676 1.00 55.88 ? 77 GLN H O 1 ATOM 3942 C CB . GLN C 2 90 ? 93.724 0.321 32.994 1.00 57.99 ? 77 GLN H CB 1 ATOM 3943 C CG . GLN C 2 90 ? 93.670 0.499 34.500 1.00 62.64 ? 77 GLN H CG 1 ATOM 3944 C CD . GLN C 2 90 ? 94.975 0.147 35.200 1.00 66.17 ? 77 GLN H CD 1 ATOM 3945 O OE1 . GLN C 2 90 ? 94.986 -0.116 36.403 1.00 68.68 ? 77 GLN H OE1 1 ATOM 3946 N NE2 . GLN C 2 90 ? 96.080 0.155 34.456 1.00 66.18 ? 77 GLN H NE2 1 ATOM 3947 N N . PHE C 2 91 ? 90.972 -1.082 32.213 1.00 49.93 ? 78 PHE H N 1 ATOM 3948 C CA . PHE C 2 91 ? 89.858 -1.895 32.646 1.00 46.43 ? 78 PHE H CA 1 ATOM 3949 C C . PHE C 2 91 ? 90.396 -3.258 33.050 1.00 47.68 ? 78 PHE H C 1 ATOM 3950 O O . PHE C 2 91 ? 91.542 -3.595 32.758 1.00 47.39 ? 78 PHE H O 1 ATOM 3951 C CB . PHE C 2 91 ? 88.791 -2.015 31.560 1.00 42.88 ? 78 PHE H CB 1 ATOM 3952 C CG . PHE C 2 91 ? 89.287 -2.539 30.251 1.00 38.28 ? 78 PHE H CG 1 ATOM 3953 C CD1 . PHE C 2 91 ? 89.921 -1.698 29.345 1.00 37.00 ? 78 PHE H CD1 1 ATOM 3954 C CD2 . PHE C 2 91 ? 89.074 -3.866 29.900 1.00 36.66 ? 78 PHE H CD2 1 ATOM 3955 C CE1 . PHE C 2 91 ? 90.332 -2.168 28.106 1.00 35.24 ? 78 PHE H CE1 1 ATOM 3956 C CE2 . PHE C 2 91 ? 89.481 -4.347 28.665 1.00 35.90 ? 78 PHE H CE2 1 ATOM 3957 C CZ . PHE C 2 91 ? 90.109 -3.498 27.766 1.00 35.27 ? 78 PHE H CZ 1 ATOM 3958 N N . SER C 2 92 ? 89.572 -4.055 33.713 1.00 48.84 ? 79 SER H N 1 ATOM 3959 C CA . SER C 2 92 ? 90.049 -5.334 34.203 1.00 49.63 ? 79 SER H CA 1 ATOM 3960 C C . SER C 2 92 ? 89.042 -6.464 34.190 1.00 49.86 ? 79 SER H C 1 ATOM 3961 O O . SER C 2 92 ? 87.847 -6.251 34.035 1.00 52.13 ? 79 SER H O 1 ATOM 3962 C CB . SER C 2 92 ? 90.528 -5.121 35.620 1.00 51.56 ? 79 SER H CB 1 ATOM 3963 O OG . SER C 2 92 ? 89.520 -4.420 36.333 1.00 54.34 ? 79 SER H OG 1 ATOM 3964 N N . LEU C 2 93 ? 89.545 -7.669 34.405 1.00 49.63 ? 80 LEU H N 1 ATOM 3965 C CA . LEU C 2 93 ? 88.728 -8.871 34.400 1.00 50.31 ? 80 LEU H CA 1 ATOM 3966 C C . LEU C 2 93 ? 88.940 -9.737 35.633 1.00 52.63 ? 80 LEU H C 1 ATOM 3967 O O . LEU C 2 93 ? 90.014 -9.752 36.230 1.00 53.86 ? 80 LEU H O 1 ATOM 3968 C CB . LEU C 2 93 ? 89.059 -9.698 33.153 1.00 47.96 ? 80 LEU H CB 1 ATOM 3969 C CG . LEU C 2 93 ? 88.504 -11.115 33.026 1.00 45.95 ? 80 LEU H CG 1 ATOM 3970 C CD1 . LEU C 2 93 ? 86.988 -11.083 33.058 1.00 44.95 ? 80 LEU H CD1 1 ATOM 3971 C CD2 . LEU C 2 93 ? 89.010 -11.740 31.732 1.00 45.98 ? 80 LEU H CD2 1 ATOM 3972 N N . LYS C 2 94 ? 87.901 -10.467 36.008 1.00 54.00 ? 81 LYS H N 1 ATOM 3973 C CA . LYS C 2 94 ? 87.977 -11.369 37.136 1.00 54.61 ? 81 LYS H CA 1 ATOM 3974 C C . LYS C 2 94 ? 87.135 -12.588 36.838 1.00 57.36 ? 81 LYS H C 1 ATOM 3975 O O . LYS C 2 94 ? 85.920 -12.497 36.645 1.00 58.83 ? 81 LYS H O 1 ATOM 3976 C CB . LYS C 2 94 ? 87.502 -10.691 38.412 1.00 52.93 ? 81 LYS H CB 1 ATOM 3977 C CG . LYS C 2 94 ? 88.597 -9.872 39.058 1.00 53.63 ? 81 LYS H CG 1 ATOM 3978 C CD . LYS C 2 94 ? 88.231 -9.436 40.471 1.00 54.17 ? 81 LYS H CD 1 ATOM 3979 C CE . LYS C 2 94 ? 89.388 -8.695 41.084 1.00 53.05 ? 81 LYS H CE 1 ATOM 3980 N NZ . LYS C 2 94 ? 89.935 -7.728 40.085 1.00 53.86 ? 81 LYS H NZ 1 ATOM 3981 N N . LEU C 2 95 ? 87.798 -13.732 36.768 1.00 58.66 ? 82 LEU H N 1 ATOM 3982 C CA . LEU C 2 95 ? 87.116 -14.978 36.493 1.00 61.24 ? 82 LEU H CA 1 ATOM 3983 C C . LEU C 2 95 ? 87.273 -15.807 37.763 1.00 63.93 ? 82 LEU H C 1 ATOM 3984 O O . LEU C 2 95 ? 88.392 -16.104 38.177 1.00 66.36 ? 82 LEU H O 1 ATOM 3985 C CB . LEU C 2 95 ? 87.774 -15.655 35.291 1.00 59.78 ? 82 LEU H CB 1 ATOM 3986 C CG . LEU C 2 95 ? 86.931 -16.682 34.534 1.00 60.29 ? 82 LEU H CG 1 ATOM 3987 C CD1 . LEU C 2 95 ? 85.599 -16.064 34.171 1.00 60.23 ? 82 LEU H CD1 1 ATOM 3988 C CD2 . LEU C 2 95 ? 87.664 -17.147 33.278 1.00 60.25 ? 82 LEU H CD2 1 ATOM 3989 N N . SER C 2 96 A 86.161 -16.164 38.399 1.00 64.99 ? 82 SER H N 1 ATOM 3990 C CA . SER C 2 96 A 86.236 -16.932 39.637 1.00 66.21 ? 82 SER H CA 1 ATOM 3991 C C . SER C 2 96 A 85.963 -18.418 39.441 1.00 68.04 ? 82 SER H C 1 ATOM 3992 O O . SER C 2 96 A 85.405 -18.830 38.413 1.00 68.67 ? 82 SER H O 1 ATOM 3993 C CB . SER C 2 96 A 85.256 -16.368 40.675 1.00 64.92 ? 82 SER H CB 1 ATOM 3994 O OG . SER C 2 96 A 83.926 -16.781 40.418 1.00 65.05 ? 82 SER H OG 1 ATOM 3995 N N . SER C 2 97 B 86.372 -19.211 40.436 1.00 68.21 ? 82 SER H N 1 ATOM 3996 C CA . SER C 2 97 B 86.177 -20.659 40.433 1.00 67.68 ? 82 SER H CA 1 ATOM 3997 C C . SER C 2 97 B 86.810 -21.319 39.216 1.00 67.48 ? 82 SER H C 1 ATOM 3998 O O . SER C 2 97 B 86.257 -22.264 38.656 1.00 68.07 ? 82 SER H O 1 ATOM 3999 C CB . SER C 2 97 B 84.681 -20.972 40.463 1.00 67.85 ? 82 SER H CB 1 ATOM 4000 O OG . SER C 2 97 B 84.031 -20.203 41.462 1.00 69.45 ? 82 SER H OG 1 ATOM 4001 N N . VAL C 2 98 C 87.972 -20.819 38.817 1.00 66.91 ? 82 VAL H N 1 ATOM 4002 C CA . VAL C 2 98 C 88.684 -21.337 37.656 1.00 67.29 ? 82 VAL H CA 1 ATOM 4003 C C . VAL C 2 98 C 88.937 -22.846 37.640 1.00 68.56 ? 82 VAL H C 1 ATOM 4004 O O . VAL C 2 98 C 89.299 -23.444 38.653 1.00 69.09 ? 82 VAL H O 1 ATOM 4005 C CB . VAL C 2 98 C 90.040 -20.616 37.484 1.00 66.79 ? 82 VAL H CB 1 ATOM 4006 C CG1 . VAL C 2 98 C 89.863 -19.361 36.657 1.00 67.05 ? 82 VAL H CG1 1 ATOM 4007 C CG2 . VAL C 2 98 C 90.594 -20.246 38.834 1.00 64.65 ? 82 VAL H CG2 1 ATOM 4008 N N . THR C 2 99 ? 88.726 -23.455 36.475 1.00 69.48 ? 83 THR H N 1 ATOM 4009 C CA . THR C 2 99 ? 88.966 -24.879 36.287 1.00 69.70 ? 83 THR H CA 1 ATOM 4010 C C . THR C 2 99 ? 89.940 -24.992 35.121 1.00 70.67 ? 83 THR H C 1 ATOM 4011 O O . THR C 2 99 ? 90.641 -24.032 34.807 1.00 71.39 ? 83 THR H O 1 ATOM 4012 C CB . THR C 2 99 ? 87.670 -25.672 35.951 1.00 68.83 ? 83 THR H CB 1 ATOM 4013 O OG1 . THR C 2 99 ? 87.256 -25.385 34.612 1.00 68.87 ? 83 THR H OG1 1 ATOM 4014 C CG2 . THR C 2 99 ? 86.560 -25.313 36.914 1.00 67.37 ? 83 THR H CG2 1 ATOM 4015 N N . ALA C 2 100 ? 89.983 -26.156 34.481 1.00 72.21 ? 84 ALA H N 1 ATOM 4016 C CA . ALA C 2 100 ? 90.891 -26.379 33.358 1.00 73.34 ? 84 ALA H CA 1 ATOM 4017 C C . ALA C 2 100 ? 90.391 -25.712 32.078 1.00 73.66 ? 84 ALA H C 1 ATOM 4018 O O . ALA C 2 100 ? 91.184 -25.374 31.193 1.00 73.84 ? 84 ALA H O 1 ATOM 4019 C CB . ALA C 2 100 ? 91.080 -27.876 33.126 1.00 73.06 ? 84 ALA H CB 1 ATOM 4020 N N . ALA C 2 101 ? 89.078 -25.531 31.976 1.00 72.95 ? 85 ALA H N 1 ATOM 4021 C CA . ALA C 2 101 ? 88.510 -24.897 30.796 1.00 72.18 ? 85 ALA H CA 1 ATOM 4022 C C . ALA C 2 101 ? 89.063 -23.482 30.686 1.00 71.05 ? 85 ALA H C 1 ATOM 4023 O O . ALA C 2 101 ? 89.669 -23.117 29.682 1.00 71.75 ? 85 ALA H O 1 ATOM 4024 C CB . ALA C 2 101 ? 86.991 -24.866 30.890 1.00 72.15 ? 85 ALA H CB 1 ATOM 4025 N N . ASP C 2 102 ? 88.875 -22.704 31.743 1.00 69.01 ? 86 ASP H N 1 ATOM 4026 C CA . ASP C 2 102 ? 89.326 -21.321 31.794 1.00 67.74 ? 86 ASP H CA 1 ATOM 4027 C C . ASP C 2 102 ? 90.826 -21.124 31.564 1.00 66.10 ? 86 ASP H C 1 ATOM 4028 O O . ASP C 2 102 ? 91.409 -20.164 32.058 1.00 65.99 ? 86 ASP H O 1 ATOM 4029 C CB . ASP C 2 102 ? 88.931 -20.726 33.143 1.00 68.53 ? 86 ASP H CB 1 ATOM 4030 C CG . ASP C 2 102 ? 87.491 -21.024 33.497 1.00 69.48 ? 86 ASP H CG 1 ATOM 4031 O OD1 . ASP C 2 102 ? 86.586 -20.514 32.806 1.00 70.21 ? 86 ASP H OD1 1 ATOM 4032 O OD2 . ASP C 2 102 ? 87.261 -21.784 34.457 1.00 70.38 ? 86 ASP H OD2 1 ATOM 4033 N N . THR C 2 103 ? 91.445 -22.019 30.804 1.00 64.15 ? 87 THR H N 1 ATOM 4034 C CA . THR C 2 103 ? 92.873 -21.925 30.526 1.00 62.25 ? 87 THR H CA 1 ATOM 4035 C C . THR C 2 103 ? 93.138 -21.474 29.096 1.00 61.07 ? 87 THR H C 1 ATOM 4036 O O . THR C 2 103 ? 92.998 -22.267 28.166 1.00 61.97 ? 87 THR H O 1 ATOM 4037 C CB . THR C 2 103 ? 93.556 -23.284 30.705 1.00 62.40 ? 87 THR H CB 1 ATOM 4038 O OG1 . THR C 2 103 ? 93.199 -23.836 31.979 1.00 63.06 ? 87 THR H OG1 1 ATOM 4039 C CG2 . THR C 2 103 ? 95.060 -23.126 30.620 1.00 60.31 ? 87 THR H CG2 1 ATOM 4040 N N . ALA C 2 104 ? 93.531 -20.218 28.911 1.00 58.54 ? 88 ALA H N 1 ATOM 4041 C CA . ALA C 2 104 ? 93.802 -19.734 27.565 1.00 56.73 ? 88 ALA H CA 1 ATOM 4042 C C . ALA C 2 104 ? 94.525 -18.405 27.533 1.00 56.03 ? 88 ALA H C 1 ATOM 4043 O O . ALA C 2 104 ? 95.023 -17.934 28.544 1.00 56.32 ? 88 ALA H O 1 ATOM 4044 C CB . ALA C 2 104 ? 92.517 -19.617 26.811 1.00 57.76 ? 88 ALA H CB 1 ATOM 4045 N N . VAL C 2 105 ? 94.585 -17.803 26.353 1.00 55.47 ? 89 VAL H N 1 ATOM 4046 C CA . VAL C 2 105 ? 95.226 -16.505 26.192 1.00 54.24 ? 89 VAL H CA 1 ATOM 4047 C C . VAL C 2 105 ? 94.115 -15.468 26.283 1.00 53.37 ? 89 VAL H C 1 ATOM 4048 O O . VAL C 2 105 ? 93.123 -15.565 25.574 1.00 53.74 ? 89 VAL H O 1 ATOM 4049 C CB . VAL C 2 105 ? 95.898 -16.388 24.826 1.00 53.95 ? 89 VAL H CB 1 ATOM 4050 C CG1 . VAL C 2 105 ? 96.815 -15.176 24.796 1.00 51.73 ? 89 VAL H CG1 1 ATOM 4051 C CG2 . VAL C 2 105 ? 96.645 -17.665 24.520 1.00 54.96 ? 89 VAL H CG2 1 ATOM 4052 N N . TYR C 2 106 ? 94.286 -14.484 27.158 1.00 52.73 ? 90 TYR H N 1 ATOM 4053 C CA . TYR C 2 106 ? 93.289 -13.446 27.370 1.00 51.98 ? 90 TYR H CA 1 ATOM 4054 C C . TYR C 2 106 ? 93.645 -12.121 26.712 1.00 53.91 ? 90 TYR H C 1 ATOM 4055 O O . TYR C 2 106 ? 94.588 -11.447 27.122 1.00 55.80 ? 90 TYR H O 1 ATOM 4056 C CB . TYR C 2 106 ? 93.085 -13.238 28.870 1.00 49.47 ? 90 TYR H CB 1 ATOM 4057 C CG . TYR C 2 106 ? 92.358 -14.381 29.526 1.00 48.26 ? 90 TYR H CG 1 ATOM 4058 C CD1 . TYR C 2 106 ? 92.962 -15.622 29.695 1.00 47.56 ? 90 TYR H CD1 1 ATOM 4059 C CD2 . TYR C 2 106 ? 91.034 -14.247 29.902 1.00 48.94 ? 90 TYR H CD2 1 ATOM 4060 C CE1 . TYR C 2 106 ? 92.256 -16.702 30.215 1.00 47.56 ? 90 TYR H CE1 1 ATOM 4061 C CE2 . TYR C 2 106 ? 90.321 -15.314 30.417 1.00 49.82 ? 90 TYR H CE2 1 ATOM 4062 C CZ . TYR C 2 106 ? 90.931 -16.538 30.569 1.00 49.47 ? 90 TYR H CZ 1 ATOM 4063 O OH . TYR C 2 106 ? 90.185 -17.588 31.057 1.00 51.30 ? 90 TYR H OH 1 ATOM 4064 N N . TYR C 2 107 ? 92.875 -11.744 25.695 1.00 53.99 ? 91 TYR H N 1 ATOM 4065 C CA . TYR C 2 107 ? 93.104 -10.495 24.979 1.00 52.88 ? 91 TYR H CA 1 ATOM 4066 C C . TYR C 2 107 ? 92.122 -9.414 25.417 1.00 52.82 ? 91 TYR H C 1 ATOM 4067 O O . TYR C 2 107 ? 90.982 -9.706 25.782 1.00 52.97 ? 91 TYR H O 1 ATOM 4068 C CB . TYR C 2 107 ? 92.893 -10.693 23.487 1.00 52.70 ? 91 TYR H CB 1 ATOM 4069 C CG . TYR C 2 107 ? 93.630 -11.834 22.855 1.00 52.59 ? 91 TYR H CG 1 ATOM 4070 C CD1 . TYR C 2 107 ? 94.857 -11.632 22.224 1.00 54.39 ? 91 TYR H CD1 1 ATOM 4071 C CD2 . TYR C 2 107 ? 93.060 -13.097 22.802 1.00 52.40 ? 91 TYR H CD2 1 ATOM 4072 C CE1 . TYR C 2 107 ? 95.493 -12.666 21.541 1.00 55.09 ? 91 TYR H CE1 1 ATOM 4073 C CE2 . TYR C 2 107 ? 93.680 -14.137 22.126 1.00 54.35 ? 91 TYR H CE2 1 ATOM 4074 C CZ . TYR C 2 107 ? 94.895 -13.919 21.492 1.00 55.50 ? 91 TYR H CZ 1 ATOM 4075 O OH . TYR C 2 107 ? 95.489 -14.950 20.789 1.00 57.00 ? 91 TYR H OH 1 ATOM 4076 N N . CYS C 2 108 ? 92.562 -8.165 25.382 1.00 51.39 ? 92 CYS H N 1 ATOM 4077 C CA . CYS C 2 108 ? 91.664 -7.083 25.707 1.00 53.36 ? 92 CYS H CA 1 ATOM 4078 C C . CYS C 2 108 ? 91.683 -6.219 24.477 1.00 53.73 ? 92 CYS H C 1 ATOM 4079 O O . CYS C 2 108 ? 92.747 -5.817 24.015 1.00 55.29 ? 92 CYS H O 1 ATOM 4080 C CB . CYS C 2 108 ? 92.112 -6.292 26.939 1.00 56.28 ? 92 CYS H CB 1 ATOM 4081 S SG . CYS C 2 108 ? 93.722 -5.420 26.961 1.00 60.07 ? 92 CYS H SG 1 ATOM 4082 N N . ALA C 2 109 ? 90.503 -5.953 23.930 1.00 52.58 ? 93 ALA H N 1 ATOM 4083 C CA . ALA C 2 109 ? 90.408 -5.158 22.721 1.00 50.18 ? 93 ALA H CA 1 ATOM 4084 C C . ALA C 2 109 ? 89.379 -4.072 22.855 1.00 48.73 ? 93 ALA H C 1 ATOM 4085 O O . ALA C 2 109 ? 88.599 -4.056 23.804 1.00 48.57 ? 93 ALA H O 1 ATOM 4086 C CB . ALA C 2 109 ? 90.043 -6.054 21.560 1.00 51.18 ? 93 ALA H CB 1 ATOM 4087 N N . ARG C 2 110 ? 89.391 -3.147 21.905 1.00 47.75 ? 94 ARG H N 1 ATOM 4088 C CA . ARG C 2 110 ? 88.402 -2.089 21.903 1.00 47.33 ? 94 ARG H CA 1 ATOM 4089 C C . ARG C 2 110 ? 87.353 -2.616 20.943 1.00 47.63 ? 94 ARG H C 1 ATOM 4090 O O . ARG C 2 110 ? 87.684 -3.312 19.974 1.00 48.96 ? 94 ARG H O 1 ATOM 4091 C CB . ARG C 2 110 ? 88.968 -0.779 21.367 1.00 46.79 ? 94 ARG H CB 1 ATOM 4092 C CG . ARG C 2 110 ? 88.019 0.381 21.623 1.00 47.54 ? 94 ARG H CG 1 ATOM 4093 C CD . ARG C 2 110 ? 88.510 1.671 21.028 1.00 45.63 ? 94 ARG H CD 1 ATOM 4094 N NE . ARG C 2 110 ? 88.570 1.584 19.577 1.00 44.38 ? 94 ARG H NE 1 ATOM 4095 C CZ . ARG C 2 110 ? 88.889 2.599 18.787 1.00 42.76 ? 94 ARG H CZ 1 ATOM 4096 N NH1 . ARG C 2 110 ? 89.179 3.782 19.313 1.00 40.38 ? 94 ARG H NH1 1 ATOM 4097 N NH2 . ARG C 2 110 ? 88.898 2.429 17.475 1.00 42.55 ? 94 ARG H NH2 1 ATOM 4098 N N . LEU C 2 111 ? 86.093 -2.294 21.203 1.00 45.99 ? 95 LEU H N 1 ATOM 4099 C CA . LEU C 2 111 ? 85.014 -2.776 20.354 1.00 43.81 ? 95 LEU H CA 1 ATOM 4100 C C . LEU C 2 111 ? 84.828 -2.022 19.037 1.00 41.45 ? 95 LEU H C 1 ATOM 4101 O O . LEU C 2 111 ? 84.722 -0.801 19.033 1.00 38.24 ? 95 LEU H O 1 ATOM 4102 C CB . LEU C 2 111 ? 83.707 -2.787 21.149 1.00 43.75 ? 95 LEU H CB 1 ATOM 4103 C CG . LEU C 2 111 ? 83.529 -3.958 22.126 1.00 44.76 ? 95 LEU H CG 1 ATOM 4104 C CD1 . LEU C 2 111 ? 83.151 -5.202 21.353 1.00 45.37 ? 95 LEU H CD1 1 ATOM 4105 C CD2 . LEU C 2 111 ? 84.793 -4.192 22.927 1.00 42.85 ? 95 LEU H CD2 1 ATOM 4106 N N . GLY C 2 112 ? 84.817 -2.808 17.948 1.00 40.22 ? 96 GLY H N 1 ATOM 4107 C CA . GLY C 2 112 ? 84.629 -2.385 16.565 1.00 38.22 ? 96 GLY H CA 1 ATOM 4108 C C . GLY C 2 112 ? 85.028 -0.984 16.226 1.00 38.44 ? 96 GLY H C 1 ATOM 4109 O O . GLY C 2 112 ? 85.177 -0.182 17.119 1.00 42.67 ? 96 GLY H O 1 ATOM 4110 N N . PRO C 2 113 ? 85.204 -0.642 14.948 1.00 37.98 ? 97 PRO H N 1 ATOM 4111 C CA . PRO C 2 113 ? 85.600 0.731 14.598 1.00 36.93 ? 97 PRO H CA 1 ATOM 4112 C C . PRO C 2 113 ? 84.557 1.830 14.810 1.00 37.63 ? 97 PRO H C 1 ATOM 4113 O O . PRO C 2 113 ? 84.900 2.981 15.043 1.00 39.22 ? 97 PRO H O 1 ATOM 4114 C CB . PRO C 2 113 ? 86.003 0.612 13.133 1.00 36.03 ? 97 PRO H CB 1 ATOM 4115 C CG . PRO C 2 113 ? 85.161 -0.516 12.633 1.00 37.56 ? 97 PRO H CG 1 ATOM 4116 C CD . PRO C 2 113 ? 85.219 -1.518 13.767 1.00 38.27 ? 97 PRO H CD 1 ATOM 4117 N N . ASP C 2 114 ? 83.282 1.480 14.743 1.00 38.61 ? 98 ASP H N 1 ATOM 4118 C CA . ASP C 2 114 ? 82.229 2.470 14.888 1.00 37.63 ? 98 ASP H CA 1 ATOM 4119 C C . ASP C 2 114 ? 81.910 2.760 16.343 1.00 38.83 ? 98 ASP H C 1 ATOM 4120 O O . ASP C 2 114 ? 82.006 1.879 17.188 1.00 39.75 ? 98 ASP H O 1 ATOM 4121 C CB . ASP C 2 114 ? 80.989 1.973 14.164 1.00 37.25 ? 98 ASP H CB 1 ATOM 4122 C CG . ASP C 2 114 ? 81.264 1.644 12.700 1.00 39.23 ? 98 ASP H CG 1 ATOM 4123 O OD1 . ASP C 2 114 ? 81.397 2.583 11.888 1.00 34.32 ? 98 ASP H OD1 1 ATOM 4124 O OD2 . ASP C 2 114 ? 81.358 0.438 12.367 1.00 42.06 ? 98 ASP H OD2 1 ATOM 4125 N N . ASP C 2 115 ? 81.542 4.005 16.632 1.00 39.09 ? 99 ASP H N 1 ATOM 4126 C CA . ASP C 2 115 ? 81.203 4.411 17.990 1.00 37.37 ? 99 ASP H CA 1 ATOM 4127 C C . ASP C 2 115 ? 80.099 3.516 18.531 1.00 35.75 ? 99 ASP H C 1 ATOM 4128 O O . ASP C 2 115 ? 79.175 3.151 17.822 1.00 35.43 ? 99 ASP H O 1 ATOM 4129 C CB . ASP C 2 115 ? 80.726 5.861 18.002 1.00 40.89 ? 99 ASP H CB 1 ATOM 4130 C CG . ASP C 2 115 ? 81.821 6.839 17.671 1.00 44.46 ? 99 ASP H CG 1 ATOM 4131 O OD1 . ASP C 2 115 ? 82.793 6.431 16.999 1.00 49.37 ? 99 ASP H OD1 1 ATOM 4132 O OD2 . ASP C 2 115 ? 81.704 8.020 18.070 1.00 45.41 ? 99 ASP H OD2 1 ATOM 4133 N N . TYR C 2 116 ? 80.211 3.169 19.801 1.00 35.14 ? 100 TYR H N 1 ATOM 4134 C CA . TYR C 2 116 ? 79.247 2.318 20.479 1.00 33.64 ? 100 TYR H CA 1 ATOM 4135 C C . TYR C 2 116 ? 79.074 0.924 19.898 1.00 33.88 ? 100 TYR H C 1 ATOM 4136 O O . TYR C 2 116 ? 78.103 0.257 20.206 1.00 35.09 ? 100 TYR H O 1 ATOM 4137 C CB . TYR C 2 116 ? 77.908 3.014 20.550 1.00 31.95 ? 100 TYR H CB 1 ATOM 4138 C CG . TYR C 2 116 ? 78.021 4.466 20.929 1.00 33.25 ? 100 TYR H CG 1 ATOM 4139 C CD1 . TYR C 2 116 ? 77.853 5.463 19.972 1.00 31.71 ? 100 TYR H CD1 1 ATOM 4140 C CD2 . TYR C 2 116 ? 78.320 4.849 22.239 1.00 33.61 ? 100 TYR H CD2 1 ATOM 4141 C CE1 . TYR C 2 116 ? 77.978 6.802 20.296 1.00 31.40 ? 100 TYR H CE1 1 ATOM 4142 C CE2 . TYR C 2 116 ? 78.452 6.199 22.578 1.00 33.72 ? 100 TYR H CE2 1 ATOM 4143 C CZ . TYR C 2 116 ? 78.282 7.170 21.592 1.00 34.16 ? 100 TYR H CZ 1 ATOM 4144 O OH . TYR C 2 116 ? 78.456 8.508 21.881 1.00 34.94 ? 100 TYR H OH 1 ATOM 4145 N N . THR C 2 117 A 80.009 0.481 19.062 1.00 35.11 ? 100 THR H N 1 ATOM 4146 C CA . THR C 2 117 A 79.947 -0.869 18.510 1.00 37.71 ? 100 THR H CA 1 ATOM 4147 C C . THR C 2 117 A 79.972 -1.815 19.709 1.00 39.89 ? 100 THR H C 1 ATOM 4148 O O . THR C 2 117 A 80.616 -1.523 20.710 1.00 42.46 ? 100 THR H O 1 ATOM 4149 C CB . THR C 2 117 A 81.175 -1.218 17.648 1.00 36.27 ? 100 THR H CB 1 ATOM 4150 O OG1 . THR C 2 117 A 81.213 -0.391 16.480 1.00 38.50 ? 100 THR H OG1 1 ATOM 4151 C CG2 . THR C 2 117 A 81.108 -2.674 17.219 1.00 35.91 ? 100 THR H CG2 1 ATOM 4152 N N . LEU C 2 118 B 79.284 -2.944 19.605 1.00 40.04 ? 100 LEU H N 1 ATOM 4153 C CA . LEU C 2 118 B 79.244 -3.904 20.690 1.00 42.46 ? 100 LEU H CA 1 ATOM 4154 C C . LEU C 2 118 B 79.377 -5.325 20.152 1.00 45.21 ? 100 LEU H C 1 ATOM 4155 O O . LEU C 2 118 B 79.135 -6.294 20.879 1.00 46.44 ? 100 LEU H O 1 ATOM 4156 C CB . LEU C 2 118 B 77.918 -3.782 21.433 1.00 44.20 ? 100 LEU H CB 1 ATOM 4157 C CG . LEU C 2 118 B 77.784 -2.949 22.704 1.00 45.62 ? 100 LEU H CG 1 ATOM 4158 C CD1 . LEU C 2 118 B 76.310 -2.657 22.954 1.00 46.42 ? 100 LEU H CD1 1 ATOM 4159 C CD2 . LEU C 2 118 B 78.384 -3.699 23.878 1.00 45.11 ? 100 LEU H CD2 1 ATOM 4160 N N . ASP C 2 119 C 79.757 -5.454 18.884 1.00 45.59 ? 100 ASP H N 1 ATOM 4161 C CA . ASP C 2 119 C 79.869 -6.769 18.278 1.00 44.67 ? 100 ASP H CA 1 ATOM 4162 C C . ASP C 2 119 C 81.137 -7.014 17.478 1.00 45.50 ? 100 ASP H C 1 ATOM 4163 O O . ASP C 2 119 C 81.258 -8.042 16.809 1.00 48.38 ? 100 ASP H O 1 ATOM 4164 C CB . ASP C 2 119 C 78.656 -7.033 17.387 1.00 45.29 ? 100 ASP H CB 1 ATOM 4165 C CG . ASP C 2 119 C 78.433 -5.941 16.351 1.00 48.44 ? 100 ASP H CG 1 ATOM 4166 O OD1 . ASP C 2 119 C 77.833 -6.237 15.303 1.00 50.15 ? 100 ASP H OD1 1 ATOM 4167 O OD2 . ASP C 2 119 C 78.839 -4.784 16.578 1.00 51.03 ? 100 ASP H OD2 1 ATOM 4168 N N . GLY C 2 120 D 82.085 -6.089 17.528 1.00 44.36 ? 100 GLY H N 1 ATOM 4169 C CA . GLY C 2 120 D 83.319 -6.298 16.790 1.00 43.74 ? 100 GLY H CA 1 ATOM 4170 C C . GLY C 2 120 D 84.469 -5.706 17.560 1.00 42.40 ? 100 GLY H C 1 ATOM 4171 O O . GLY C 2 120 D 84.222 -4.843 18.378 1.00 43.37 ? 100 GLY H O 1 ATOM 4172 N N . MET C 2 121 E 85.699 -6.175 17.351 1.00 42.25 ? 100 MET H N 1 ATOM 4173 C CA . MET C 2 121 E 86.861 -5.603 18.054 1.00 42.78 ? 100 MET H CA 1 ATOM 4174 C C . MET C 2 121 E 87.886 -5.146 17.024 1.00 42.54 ? 100 MET H C 1 ATOM 4175 O O . MET C 2 121 E 88.501 -5.974 16.364 1.00 42.53 ? 100 MET H O 1 ATOM 4176 C CB . MET C 2 121 E 87.530 -6.620 18.985 1.00 42.84 ? 100 MET H CB 1 ATOM 4177 C CG . MET C 2 121 E 86.861 -7.974 19.116 1.00 44.25 ? 100 MET H CG 1 ATOM 4178 S SD . MET C 2 121 E 85.370 -7.996 20.121 1.00 46.17 ? 100 MET H SD 1 ATOM 4179 C CE . MET C 2 121 E 84.210 -8.693 18.905 1.00 48.32 ? 100 MET H CE 1 ATOM 4180 N N . ASP C 2 122 ? 88.087 -3.840 16.885 1.00 43.43 ? 101 ASP H N 1 ATOM 4181 C CA . ASP C 2 122 ? 89.029 -3.358 15.883 1.00 48.04 ? 101 ASP H CA 1 ATOM 4182 C C . ASP C 2 122 ? 90.491 -3.309 16.325 1.00 50.09 ? 101 ASP H C 1 ATOM 4183 O O . ASP C 2 122 ? 91.395 -3.480 15.511 1.00 49.91 ? 101 ASP H O 1 ATOM 4184 C CB . ASP C 2 122 ? 88.590 -1.984 15.358 1.00 50.27 ? 101 ASP H CB 1 ATOM 4185 C CG . ASP C 2 122 ? 88.575 -0.920 16.434 1.00 52.80 ? 101 ASP H CG 1 ATOM 4186 O OD1 . ASP C 2 122 ? 88.771 -1.268 17.622 1.00 53.04 ? 101 ASP H OD1 1 ATOM 4187 O OD2 . ASP C 2 122 ? 88.357 0.266 16.084 1.00 52.49 ? 101 ASP H OD2 1 ATOM 4188 N N . VAL C 2 123 ? 90.725 -3.084 17.611 1.00 52.26 ? 102 VAL H N 1 ATOM 4189 C CA . VAL C 2 123 ? 92.081 -3.029 18.126 1.00 53.83 ? 102 VAL H CA 1 ATOM 4190 C C . VAL C 2 123 ? 92.247 -3.982 19.300 1.00 56.11 ? 102 VAL H C 1 ATOM 4191 O O . VAL C 2 123 ? 91.553 -3.854 20.315 1.00 56.95 ? 102 VAL H O 1 ATOM 4192 C CB . VAL C 2 123 ? 92.437 -1.617 18.579 1.00 53.81 ? 102 VAL H CB 1 ATOM 4193 C CG1 . VAL C 2 123 ? 93.867 -1.591 19.095 1.00 52.88 ? 102 VAL H CG1 1 ATOM 4194 C CG2 . VAL C 2 123 ? 92.239 -0.642 17.422 1.00 52.42 ? 102 VAL H CG2 1 ATOM 4195 N N . TRP C 2 124 ? 93.186 -4.919 19.154 1.00 57.57 ? 103 TRP H N 1 ATOM 4196 C CA . TRP C 2 124 ? 93.464 -5.937 20.166 1.00 57.48 ? 103 TRP H CA 1 ATOM 4197 C C . TRP C 2 124 ? 94.771 -5.791 20.943 1.00 59.60 ? 103 TRP H C 1 ATOM 4198 O O . TRP C 2 124 ? 95.743 -5.211 20.468 1.00 59.34 ? 103 TRP H O 1 ATOM 4199 C CB . TRP C 2 124 ? 93.453 -7.312 19.517 1.00 54.85 ? 103 TRP H CB 1 ATOM 4200 C CG . TRP C 2 124 ? 92.141 -7.698 18.925 1.00 53.11 ? 103 TRP H CG 1 ATOM 4201 C CD1 . TRP C 2 124 ? 91.403 -6.984 18.026 1.00 51.90 ? 103 TRP H CD1 1 ATOM 4202 C CD2 . TRP C 2 124 ? 91.444 -8.931 19.130 1.00 50.87 ? 103 TRP H CD2 1 ATOM 4203 N NE1 . TRP C 2 124 ? 90.291 -7.701 17.654 1.00 52.00 ? 103 TRP H NE1 1 ATOM 4204 C CE2 . TRP C 2 124 ? 90.293 -8.900 18.317 1.00 50.63 ? 103 TRP H CE2 1 ATOM 4205 C CE3 . TRP C 2 124 ? 91.684 -10.061 19.918 1.00 50.25 ? 103 TRP H CE3 1 ATOM 4206 C CZ2 . TRP C 2 124 ? 89.382 -9.957 18.268 1.00 51.12 ? 103 TRP H CZ2 1 ATOM 4207 C CZ3 . TRP C 2 124 ? 90.778 -11.114 19.869 1.00 51.81 ? 103 TRP H CZ3 1 ATOM 4208 C CH2 . TRP C 2 124 ? 89.641 -11.053 19.048 1.00 51.75 ? 103 TRP H CH2 1 ATOM 4209 N N . GLY C 2 125 ? 94.780 -6.345 22.148 1.00 62.59 ? 104 GLY H N 1 ATOM 4210 C CA . GLY C 2 125 ? 95.965 -6.289 22.979 1.00 65.58 ? 104 GLY H CA 1 ATOM 4211 C C . GLY C 2 125 ? 96.938 -7.360 22.535 1.00 68.30 ? 104 GLY H C 1 ATOM 4212 O O . GLY C 2 125 ? 96.585 -8.225 21.732 1.00 69.10 ? 104 GLY H O 1 ATOM 4213 N N . GLN C 2 126 ? 98.158 -7.303 23.066 1.00 69.94 ? 105 GLN H N 1 ATOM 4214 C CA . GLN C 2 126 ? 99.224 -8.247 22.734 1.00 69.47 ? 105 GLN H CA 1 ATOM 4215 C C . GLN C 2 126 ? 98.811 -9.690 23.014 1.00 68.43 ? 105 GLN H C 1 ATOM 4216 O O . GLN C 2 126 ? 99.106 -10.592 22.236 1.00 67.62 ? 105 GLN H O 1 ATOM 4217 C CB . GLN C 2 126 ? 100.476 -7.871 23.540 1.00 72.84 ? 105 GLN H CB 1 ATOM 4218 C CG . GLN C 2 126 ? 101.776 -8.578 23.154 1.00 77.44 ? 105 GLN H CG 1 ATOM 4219 C CD . GLN C 2 126 ? 102.094 -9.777 24.042 1.00 79.63 ? 105 GLN H CD 1 ATOM 4220 O OE1 . GLN C 2 126 ? 101.973 -9.706 25.272 1.00 80.75 ? 105 GLN H OE1 1 ATOM 4221 N NE2 . GLN C 2 126 ? 102.520 -10.880 23.424 1.00 79.77 ? 105 GLN H NE2 1 ATOM 4222 N N . GLY C 2 127 ? 98.105 -9.895 24.118 1.00 68.18 ? 106 GLY H N 1 ATOM 4223 C CA . GLY C 2 127 ? 97.677 -11.231 24.487 1.00 68.95 ? 106 GLY H CA 1 ATOM 4224 C C . GLY C 2 127 ? 98.287 -11.585 25.831 1.00 70.24 ? 106 GLY H C 1 ATOM 4225 O O . GLY C 2 127 ? 99.249 -10.945 26.261 1.00 71.92 ? 106 GLY H O 1 ATOM 4226 N N . THR C 2 128 ? 97.742 -12.594 26.503 1.00 69.34 ? 107 THR H N 1 ATOM 4227 C CA . THR C 2 128 ? 98.257 -13.003 27.804 1.00 69.34 ? 107 THR H CA 1 ATOM 4228 C C . THR C 2 128 ? 97.824 -14.415 28.106 1.00 70.71 ? 107 THR H C 1 ATOM 4229 O O . THR C 2 128 ? 96.638 -14.717 28.060 1.00 72.77 ? 107 THR H O 1 ATOM 4230 C CB . THR C 2 128 ? 97.724 -12.100 28.924 1.00 69.12 ? 107 THR H CB 1 ATOM 4231 O OG1 . THR C 2 128 ? 98.409 -10.845 28.889 1.00 69.81 ? 107 THR H OG1 1 ATOM 4232 C CG2 . THR C 2 128 ? 97.927 -12.749 30.282 1.00 69.35 ? 107 THR H CG2 1 ATOM 4233 N N . THR C 2 129 ? 98.770 -15.285 28.427 1.00 70.85 ? 108 THR H N 1 ATOM 4234 C CA . THR C 2 129 ? 98.396 -16.653 28.721 1.00 70.96 ? 108 THR H CA 1 ATOM 4235 C C . THR C 2 129 ? 98.027 -16.805 30.180 1.00 71.73 ? 108 THR H C 1 ATOM 4236 O O . THR C 2 129 ? 98.498 -16.059 31.030 1.00 71.52 ? 108 THR H O 1 ATOM 4237 C CB . THR C 2 129 ? 99.515 -17.620 28.402 1.00 70.72 ? 108 THR H CB 1 ATOM 4238 O OG1 . THR C 2 129 ? 100.042 -17.317 27.106 1.00 71.34 ? 108 THR H OG1 1 ATOM 4239 C CG2 . THR C 2 129 ? 98.979 -19.051 28.408 1.00 70.49 ? 108 THR H CG2 1 ATOM 4240 N N . VAL C 2 130 ? 97.168 -17.773 30.460 1.00 73.60 ? 109 VAL H N 1 ATOM 4241 C CA . VAL C 2 130 ? 96.729 -18.030 31.815 1.00 76.15 ? 109 VAL H CA 1 ATOM 4242 C C . VAL C 2 130 ? 96.413 -19.504 31.988 1.00 79.63 ? 109 VAL H C 1 ATOM 4243 O O . VAL C 2 130 ? 95.357 -19.996 31.576 1.00 78.58 ? 109 VAL H O 1 ATOM 4244 C CB . VAL C 2 130 ? 95.504 -17.171 32.181 1.00 75.37 ? 109 VAL H CB 1 ATOM 4245 C CG1 . VAL C 2 130 ? 94.726 -17.813 33.311 1.00 75.19 ? 109 VAL H CG1 1 ATOM 4246 C CG2 . VAL C 2 130 ? 95.969 -15.783 32.609 1.00 74.84 ? 109 VAL H CG2 1 ATOM 4247 N N . THR C 2 131 ? 97.372 -20.190 32.606 1.00 83.79 ? 110 THR H N 1 ATOM 4248 C CA . THR C 2 131 ? 97.312 -21.616 32.886 1.00 85.84 ? 110 THR H CA 1 ATOM 4249 C C . THR C 2 131 ? 96.831 -21.878 34.309 1.00 88.12 ? 110 THR H C 1 ATOM 4250 O O . THR C 2 131 ? 97.354 -21.299 35.263 1.00 87.61 ? 110 THR H O 1 ATOM 4251 C CB . THR C 2 131 ? 98.708 -22.243 32.711 1.00 84.98 ? 110 THR H CB 1 ATOM 4252 O OG1 . THR C 2 131 ? 99.705 -21.224 32.888 1.00 82.78 ? 110 THR H OG1 1 ATOM 4253 C CG2 . THR C 2 131 ? 98.852 -22.870 31.332 1.00 83.82 ? 110 THR H CG2 1 ATOM 4254 N N . VAL C 2 132 ? 95.827 -22.740 34.442 1.00 90.88 ? 111 VAL H N 1 ATOM 4255 C CA . VAL C 2 132 ? 95.304 -23.091 35.753 1.00 94.37 ? 111 VAL H CA 1 ATOM 4256 C C . VAL C 2 132 ? 96.087 -24.285 36.290 1.00 97.49 ? 111 VAL H C 1 ATOM 4257 O O . VAL C 2 132 ? 95.637 -25.429 36.198 1.00 98.79 ? 111 VAL H O 1 ATOM 4258 C CB . VAL C 2 132 ? 93.795 -23.455 35.709 1.00 93.82 ? 111 VAL H CB 1 ATOM 4259 C CG1 . VAL C 2 132 ? 92.970 -22.224 35.411 1.00 93.89 ? 111 VAL H CG1 1 ATOM 4260 C CG2 . VAL C 2 132 ? 93.541 -24.523 34.665 1.00 94.50 ? 111 VAL H CG2 1 ATOM 4261 N N . SER C 2 133 ? 97.269 -24.010 36.841 1.00 100.40 ? 112 SER H N 1 ATOM 4262 C CA . SER C 2 133 ? 98.131 -25.049 37.405 1.00 101.74 ? 112 SER H CA 1 ATOM 4263 C C . SER C 2 133 ? 97.748 -25.362 38.855 1.00 103.34 ? 112 SER H C 1 ATOM 4264 O O . SER C 2 133 ? 96.722 -24.894 39.353 1.00 103.05 ? 112 SER H O 1 ATOM 4265 C CB . SER C 2 133 ? 99.592 -24.609 37.344 1.00 100.97 ? 112 SER H CB 1 ATOM 4266 O OG . SER C 2 133 ? 100.445 -25.637 37.810 1.00 100.96 ? 112 SER H OG 1 ATOM 4267 N N . SER C 2 134 ? 98.578 -26.149 39.534 1.00 105.32 ? 113 SER H N 1 ATOM 4268 C CA . SER C 2 134 ? 98.291 -26.519 40.916 1.00 107.01 ? 113 SER H CA 1 ATOM 4269 C C . SER C 2 134 ? 99.529 -26.697 41.787 1.00 107.71 ? 113 SER H C 1 ATOM 4270 O O . SER C 2 134 ? 99.418 -26.846 43.005 1.00 108.14 ? 113 SER H O 1 ATOM 4271 C CB . SER C 2 134 ? 97.457 -27.808 40.943 1.00 107.29 ? 113 SER H CB 1 ATOM 4272 O OG . SER C 2 134 ? 98.090 -28.852 40.221 1.00 106.77 ? 113 SER H OG 1 ATOM 4273 N N . GLY C 2 135 ? 100.706 -26.671 41.171 1.00 108.50 ? 114 GLY H N 1 ATOM 4274 C CA . GLY C 2 135 ? 101.928 -26.858 41.933 1.00 109.99 ? 114 GLY H CA 1 ATOM 4275 C C . GLY C 2 135 ? 102.631 -25.590 42.373 1.00 110.70 ? 114 GLY H C 1 ATOM 4276 O O . GLY C 2 135 ? 103.547 -25.646 43.196 1.00 110.73 ? 114 GLY H O 1 ATOM 4277 N N . SER C 2 136 ? 102.201 -24.457 41.825 1.00 110.99 ? 115 SER H N 1 ATOM 4278 C CA . SER C 2 136 ? 102.773 -23.146 42.134 1.00 112.21 ? 115 SER H CA 1 ATOM 4279 C C . SER C 2 136 ? 103.989 -22.853 41.259 1.00 112.82 ? 115 SER H C 1 ATOM 4280 O O . SER C 2 136 ? 104.746 -23.753 40.896 1.00 111.99 ? 115 SER H O 1 ATOM 4281 C CB . SER C 2 136 ? 103.159 -23.043 43.617 1.00 112.56 ? 115 SER H CB 1 ATOM 4282 O OG . SER C 2 136 ? 103.601 -21.735 43.947 1.00 112.22 ? 115 SER H OG 1 ATOM 4283 N N . ALA C 2 137 ? 104.161 -21.577 40.930 1.00 114.15 ? 116 ALA H N 1 ATOM 4284 C CA . ALA C 2 137 ? 105.253 -21.125 40.078 1.00 115.39 ? 116 ALA H CA 1 ATOM 4285 C C . ALA C 2 137 ? 106.621 -21.522 40.597 1.00 116.06 ? 116 ALA H C 1 ATOM 4286 O O . ALA C 2 137 ? 106.746 -22.137 41.654 1.00 115.62 ? 116 ALA H O 1 ATOM 4287 C CB . ALA C 2 137 ? 105.182 -19.613 39.903 1.00 115.47 ? 116 ALA H CB 1 ATOM 4288 N N . SER C 2 138 ? 107.644 -21.158 39.832 1.00 117.52 ? 117 SER H N 1 ATOM 4289 C CA . SER C 2 138 ? 109.028 -21.454 40.170 1.00 119.53 ? 117 SER H CA 1 ATOM 4290 C C . SER C 2 138 ? 109.946 -20.959 39.054 1.00 121.22 ? 117 SER H C 1 ATOM 4291 O O . SER C 2 138 ? 109.667 -21.164 37.873 1.00 121.64 ? 117 SER H O 1 ATOM 4292 C CB . SER C 2 138 ? 109.214 -22.963 40.377 1.00 119.14 ? 117 SER H CB 1 ATOM 4293 O OG . SER C 2 138 ? 108.766 -23.705 39.256 1.00 118.33 ? 117 SER H OG 1 ATOM 4294 N N . ALA C 2 139 ? 111.035 -20.299 39.434 1.00 122.98 ? 118 ALA H N 1 ATOM 4295 C CA . ALA C 2 139 ? 111.992 -19.773 38.467 1.00 124.57 ? 118 ALA H CA 1 ATOM 4296 C C . ALA C 2 139 ? 112.703 -20.903 37.716 1.00 126.05 ? 118 ALA H C 1 ATOM 4297 O O . ALA C 2 139 ? 112.511 -22.080 38.022 1.00 125.68 ? 118 ALA H O 1 ATOM 4298 C CB . ALA C 2 139 ? 113.006 -18.893 39.179 1.00 124.62 ? 118 ALA H CB 1 ATOM 4299 N N . PRO C 2 140 ? 113.529 -20.555 36.714 1.00 127.85 ? 119 PRO H N 1 ATOM 4300 C CA . PRO C 2 140 ? 114.263 -21.551 35.924 1.00 129.92 ? 119 PRO H CA 1 ATOM 4301 C C . PRO C 2 140 ? 115.698 -21.843 36.392 1.00 131.87 ? 119 PRO H C 1 ATOM 4302 O O . PRO C 2 140 ? 116.227 -21.172 37.280 1.00 132.15 ? 119 PRO H O 1 ATOM 4303 C CB . PRO C 2 140 ? 114.237 -20.941 34.530 1.00 129.41 ? 119 PRO H CB 1 ATOM 4304 C CG . PRO C 2 140 ? 114.452 -19.491 34.835 1.00 128.61 ? 119 PRO H CG 1 ATOM 4305 C CD . PRO C 2 140 ? 113.540 -19.246 36.032 1.00 128.01 ? 119 PRO H CD 1 ATOM 4306 N N . THR C 2 141 ? 116.314 -22.851 35.776 1.00 133.76 ? 120 THR H N 1 ATOM 4307 C CA . THR C 2 141 ? 117.687 -23.252 36.081 1.00 135.45 ? 120 THR H CA 1 ATOM 4308 C C . THR C 2 141 ? 118.395 -23.568 34.762 1.00 136.92 ? 120 THR H C 1 ATOM 4309 O O . THR C 2 141 ? 118.161 -24.617 34.162 1.00 136.92 ? 120 THR H O 1 ATOM 4310 C CB . THR C 2 141 ? 117.727 -24.510 36.981 1.00 135.37 ? 120 THR H CB 1 ATOM 4311 O OG1 . THR C 2 141 ? 117.171 -25.626 36.275 1.00 134.92 ? 120 THR H OG1 1 ATOM 4312 C CG2 . THR C 2 141 ? 116.927 -24.282 38.257 1.00 135.41 ? 120 THR H CG2 1 ATOM 4313 N N . LEU C 2 142 ? 119.257 -22.656 34.319 1.00 138.95 ? 121 LEU H N 1 ATOM 4314 C CA . LEU C 2 142 ? 119.990 -22.812 33.058 1.00 141.45 ? 121 LEU H CA 1 ATOM 4315 C C . LEU C 2 142 ? 121.213 -23.735 33.108 1.00 143.10 ? 121 LEU H C 1 ATOM 4316 O O . LEU C 2 142 ? 121.790 -23.972 34.172 1.00 143.81 ? 121 LEU H O 1 ATOM 4317 C CB . LEU C 2 142 ? 120.435 -21.438 32.548 1.00 141.43 ? 121 LEU H CB 1 ATOM 4318 C CG . LEU C 2 142 ? 119.374 -20.464 32.034 1.00 141.91 ? 121 LEU H CG 1 ATOM 4319 C CD1 . LEU C 2 142 ? 119.967 -19.069 31.947 1.00 141.94 ? 121 LEU H CD1 1 ATOM 4320 C CD2 . LEU C 2 142 ? 118.870 -20.923 30.674 1.00 142.27 ? 121 LEU H CD2 1 ATOM 4321 N N . PHE C 2 143 ? 121.601 -24.249 31.941 1.00 144.47 ? 122 PHE H N 1 ATOM 4322 C CA . PHE C 2 143 ? 122.762 -25.130 31.811 1.00 145.59 ? 122 PHE H CA 1 ATOM 4323 C C . PHE C 2 143 ? 123.446 -24.925 30.463 1.00 146.39 ? 122 PHE H C 1 ATOM 4324 O O . PHE C 2 143 ? 122.865 -25.214 29.418 1.00 146.24 ? 122 PHE H O 1 ATOM 4325 C CB . PHE C 2 143 ? 122.359 -26.603 31.943 1.00 145.74 ? 122 PHE H CB 1 ATOM 4326 C CG . PHE C 2 143 ? 121.893 -26.985 33.316 1.00 146.53 ? 122 PHE H CG 1 ATOM 4327 C CD1 . PHE C 2 143 ? 120.566 -26.810 33.690 1.00 147.14 ? 122 PHE H CD1 1 ATOM 4328 C CD2 . PHE C 2 143 ? 122.789 -27.495 34.248 1.00 147.02 ? 122 PHE H CD2 1 ATOM 4329 C CE1 . PHE C 2 143 ? 120.137 -27.137 34.976 1.00 147.73 ? 122 PHE H CE1 1 ATOM 4330 C CE2 . PHE C 2 143 ? 122.372 -27.825 35.537 1.00 147.34 ? 122 PHE H CE2 1 ATOM 4331 C CZ . PHE C 2 143 ? 121.044 -27.645 35.901 1.00 147.47 ? 122 PHE H CZ 1 ATOM 4332 N N . PRO C 2 144 ? 124.694 -24.425 30.470 1.00 147.40 ? 123 PRO H N 1 ATOM 4333 C CA . PRO C 2 144 ? 125.441 -24.193 29.228 1.00 147.99 ? 123 PRO H CA 1 ATOM 4334 C C . PRO C 2 144 ? 125.568 -25.467 28.395 1.00 148.28 ? 123 PRO H C 1 ATOM 4335 O O . PRO C 2 144 ? 126.198 -26.439 28.817 1.00 148.33 ? 123 PRO H O 1 ATOM 4336 C CB . PRO C 2 144 ? 126.791 -23.678 29.728 1.00 148.15 ? 123 PRO H CB 1 ATOM 4337 C CG . PRO C 2 144 ? 126.927 -24.326 31.075 1.00 148.16 ? 123 PRO H CG 1 ATOM 4338 C CD . PRO C 2 144 ? 125.540 -24.149 31.642 1.00 147.97 ? 123 PRO H CD 1 ATOM 4339 N N . LEU C 2 145 ? 124.963 -25.446 27.210 1.00 148.41 ? 124 LEU H N 1 ATOM 4340 C CA . LEU C 2 145 ? 124.964 -26.588 26.300 1.00 148.15 ? 124 LEU H CA 1 ATOM 4341 C C . LEU C 2 145 ? 126.285 -26.792 25.554 1.00 147.73 ? 124 LEU H C 1 ATOM 4342 O O . LEU C 2 145 ? 127.189 -25.958 25.630 1.00 147.51 ? 124 LEU H O 1 ATOM 4343 C CB . LEU C 2 145 ? 123.818 -26.439 25.291 1.00 148.21 ? 124 LEU H CB 1 ATOM 4344 C CG . LEU C 2 145 ? 122.401 -26.312 25.861 1.00 148.12 ? 124 LEU H CG 1 ATOM 4345 C CD1 . LEU C 2 145 ? 121.426 -26.055 24.728 1.00 148.00 ? 124 LEU H CD1 1 ATOM 4346 C CD2 . LEU C 2 145 ? 122.021 -27.576 26.618 1.00 147.97 ? 124 LEU H CD2 1 ATOM 4347 N N . VAL C 2 146 ? 126.380 -27.911 24.836 1.00 147.27 ? 125 VAL H N 1 ATOM 4348 C CA . VAL C 2 146 ? 127.573 -28.267 24.066 1.00 146.65 ? 125 VAL H CA 1 ATOM 4349 C C . VAL C 2 146 ? 127.504 -27.696 22.650 1.00 146.43 ? 125 VAL H C 1 ATOM 4350 O O . VAL C 2 146 ? 128.470 -27.762 21.888 1.00 145.71 ? 125 VAL H O 1 ATOM 4351 C CB . VAL C 2 146 ? 127.728 -29.804 23.971 1.00 146.41 ? 125 VAL H CB 1 ATOM 4352 C CG1 . VAL C 2 146 ? 129.036 -30.162 23.275 1.00 146.18 ? 125 VAL H CG1 1 ATOM 4353 C CG2 . VAL C 2 146 ? 127.674 -30.417 25.359 1.00 145.76 ? 125 VAL H CG2 1 ATOM 4354 N N . SER C 2 151 ? 132.872 -24.678 9.382 1.00 140.63 ? 134 SER H N 1 ATOM 4355 C CA . SER C 2 151 ? 132.249 -23.361 9.351 1.00 140.61 ? 134 SER H CA 1 ATOM 4356 C C . SER C 2 151 ? 130.786 -23.438 9.784 1.00 140.77 ? 134 SER H C 1 ATOM 4357 O O . SER C 2 151 ? 130.097 -24.420 9.497 1.00 140.54 ? 134 SER H O 1 ATOM 4358 C CB . SER C 2 151 ? 132.325 -22.775 7.940 1.00 140.33 ? 134 SER H CB 1 ATOM 4359 O OG . SER C 2 151 ? 131.494 -23.498 7.048 1.00 139.56 ? 134 SER H OG 1 ATOM 4360 N N . SER C 2 152 ? 130.327 -22.394 10.474 1.00 140.74 ? 135 SER H N 1 ATOM 4361 C CA . SER C 2 152 ? 128.948 -22.295 10.954 1.00 140.47 ? 135 SER H CA 1 ATOM 4362 C C . SER C 2 152 ? 128.652 -23.195 12.156 1.00 140.45 ? 135 SER H C 1 ATOM 4363 O O . SER C 2 152 ? 127.888 -24.156 12.045 1.00 140.42 ? 135 SER H O 1 ATOM 4364 C CB . SER C 2 152 ? 127.967 -22.621 9.820 1.00 140.20 ? 135 SER H CB 1 ATOM 4365 O OG . SER C 2 152 ? 128.151 -21.761 8.708 1.00 139.68 ? 135 SER H OG 1 ATOM 4366 N N . VAL C 2 153 ? 129.250 -22.878 13.303 1.00 140.29 ? 136 VAL H N 1 ATOM 4367 C CA . VAL C 2 153 ? 129.039 -23.658 14.521 1.00 139.93 ? 136 VAL H CA 1 ATOM 4368 C C . VAL C 2 153 ? 128.304 -22.810 15.554 1.00 140.16 ? 136 VAL H C 1 ATOM 4369 O O . VAL C 2 153 ? 128.412 -21.583 15.541 1.00 140.43 ? 136 VAL H O 1 ATOM 4370 C CB . VAL C 2 153 ? 130.376 -24.126 15.131 1.00 139.51 ? 136 VAL H CB 1 ATOM 4371 C CG1 . VAL C 2 153 ? 131.125 -22.940 15.717 1.00 139.18 ? 136 VAL H CG1 1 ATOM 4372 C CG2 . VAL C 2 153 ? 130.122 -25.186 16.188 1.00 139.10 ? 136 VAL H CG2 1 ATOM 4373 N N . ALA C 2 154 ? 127.564 -23.460 16.449 1.00 140.09 ? 137 ALA H N 1 ATOM 4374 C CA . ALA C 2 154 ? 126.809 -22.740 17.471 1.00 140.04 ? 137 ALA H CA 1 ATOM 4375 C C . ALA C 2 154 ? 126.348 -23.620 18.625 1.00 140.00 ? 137 ALA H C 1 ATOM 4376 O O . ALA C 2 154 ? 126.511 -24.840 18.599 1.00 139.50 ? 137 ALA H O 1 ATOM 4377 C CB . ALA C 2 154 ? 125.609 -22.069 16.837 1.00 140.14 ? 137 ALA H CB 1 ATOM 4378 N N . VAL C 2 155 ? 125.765 -22.979 19.637 1.00 140.28 ? 138 VAL H N 1 ATOM 4379 C CA . VAL C 2 155 ? 125.258 -23.670 20.820 1.00 140.75 ? 138 VAL H CA 1 ATOM 4380 C C . VAL C 2 155 ? 124.141 -22.870 21.484 1.00 140.38 ? 138 VAL H C 1 ATOM 4381 O O . VAL C 2 155 ? 123.817 -21.760 21.057 1.00 140.36 ? 138 VAL H O 1 ATOM 4382 C CB . VAL C 2 155 ? 126.364 -23.892 21.871 1.00 141.29 ? 138 VAL H CB 1 ATOM 4383 C CG1 . VAL C 2 155 ? 127.416 -24.851 21.335 1.00 141.80 ? 138 VAL H CG1 1 ATOM 4384 C CG2 . VAL C 2 155 ? 126.991 -22.560 22.243 1.00 141.97 ? 138 VAL H CG2 1 ATOM 4385 N N . GLY C 2 156 ? 123.565 -23.440 22.539 1.00 140.04 ? 139 GLY H N 1 ATOM 4386 C CA . GLY C 2 156 ? 122.488 -22.772 23.246 1.00 139.71 ? 139 GLY H CA 1 ATOM 4387 C C . GLY C 2 156 ? 122.588 -22.893 24.754 1.00 139.13 ? 139 GLY H C 1 ATOM 4388 O O . GLY C 2 156 ? 123.681 -23.048 25.298 1.00 139.01 ? 139 GLY H O 1 ATOM 4389 N N . CYS C 2 157 ? 121.445 -22.819 25.430 1.00 138.47 ? 140 CYS H N 1 ATOM 4390 C CA . CYS C 2 157 ? 121.408 -22.920 26.883 1.00 137.70 ? 140 CYS H CA 1 ATOM 4391 C C . CYS C 2 157 ? 120.067 -23.398 27.424 1.00 136.46 ? 140 CYS H C 1 ATOM 4392 O O . CYS C 2 157 ? 119.174 -22.600 27.703 1.00 136.36 ? 140 CYS H O 1 ATOM 4393 C CB . CYS C 2 157 ? 121.782 -21.575 27.515 1.00 138.79 ? 140 CYS H CB 1 ATOM 4394 S SG . CYS C 2 157 ? 121.072 -20.103 26.711 1.00 139.83 ? 140 CYS H SG 1 ATOM 4395 N N . LEU C 2 158 ? 119.947 -24.713 27.573 1.00 135.16 ? 141 LEU H N 1 ATOM 4396 C CA . LEU C 2 158 ? 118.738 -25.343 28.090 1.00 134.16 ? 141 LEU H CA 1 ATOM 4397 C C . LEU C 2 158 ? 118.289 -24.680 29.390 1.00 133.80 ? 141 LEU H C 1 ATOM 4398 O O . LEU C 2 158 ? 118.976 -23.810 29.919 1.00 133.94 ? 141 LEU H O 1 ATOM 4399 C CB . LEU C 2 158 ? 119.005 -26.828 28.338 1.00 133.94 ? 141 LEU H CB 1 ATOM 4400 C CG . LEU C 2 158 ? 117.863 -27.667 28.911 1.00 134.14 ? 141 LEU H CG 1 ATOM 4401 C CD1 . LEU C 2 158 ? 116.712 -27.725 27.916 1.00 134.19 ? 141 LEU H CD1 1 ATOM 4402 C CD2 . LEU C 2 158 ? 118.369 -29.062 29.224 1.00 134.27 ? 141 LEU H CD2 1 ATOM 4403 N N . ALA C 2 159 ? 117.132 -25.097 29.899 1.00 133.26 ? 142 ALA H N 1 ATOM 4404 C CA . ALA C 2 159 ? 116.586 -24.553 31.138 1.00 132.62 ? 142 ALA H CA 1 ATOM 4405 C C . ALA C 2 159 ? 115.277 -25.245 31.502 1.00 132.56 ? 142 ALA H C 1 ATOM 4406 O O . ALA C 2 159 ? 114.295 -25.152 30.767 1.00 132.76 ? 142 ALA H O 1 ATOM 4407 C CB . ALA C 2 159 ? 116.356 -23.056 30.994 1.00 132.07 ? 142 ALA H CB 1 ATOM 4408 N N . GLN C 2 160 ? 115.268 -25.939 32.636 1.00 132.81 ? 143 GLN H N 1 ATOM 4409 C CA . GLN C 2 160 ? 114.074 -26.641 33.102 1.00 132.81 ? 143 GLN H CA 1 ATOM 4410 C C . GLN C 2 160 ? 113.606 -26.009 34.412 1.00 133.05 ? 143 GLN H C 1 ATOM 4411 O O . GLN C 2 160 ? 113.958 -24.869 34.718 1.00 132.79 ? 143 GLN H O 1 ATOM 4412 C CB . GLN C 2 160 ? 114.374 -28.129 33.337 1.00 132.77 ? 143 GLN H CB 1 ATOM 4413 C CG . GLN C 2 160 ? 115.079 -28.853 32.183 1.00 133.03 ? 143 GLN H CG 1 ATOM 4414 C CD . GLN C 2 160 ? 116.598 -28.671 32.182 1.00 132.79 ? 143 GLN H CD 1 ATOM 4415 O OE1 . GLN C 2 160 ? 117.110 -27.562 32.008 1.00 132.06 ? 143 GLN H OE1 1 ATOM 4416 N NE2 . GLN C 2 160 ? 117.321 -29.770 32.374 1.00 132.05 ? 143 GLN H NE2 1 ATOM 4417 N N . ASP C 2 161 ? 112.807 -26.752 35.174 1.00 133.58 ? 144 ASP H N 1 ATOM 4418 C CA . ASP C 2 161 ? 112.299 -26.289 36.467 1.00 134.24 ? 144 ASP H CA 1 ATOM 4419 C C . ASP C 2 161 ? 111.085 -25.355 36.404 1.00 133.86 ? 144 ASP H C 1 ATOM 4420 O O . ASP C 2 161 ? 110.035 -25.667 36.971 1.00 133.40 ? 144 ASP H O 1 ATOM 4421 C CB . ASP C 2 161 ? 113.430 -25.612 37.261 1.00 135.76 ? 144 ASP H CB 1 ATOM 4422 C CG . ASP C 2 161 ? 113.040 -25.301 38.702 1.00 137.10 ? 144 ASP H CG 1 ATOM 4423 O OD1 . ASP C 2 161 ? 113.895 -24.779 39.452 1.00 137.23 ? 144 ASP H OD1 1 ATOM 4424 O OD2 . ASP C 2 161 ? 111.884 -25.580 39.086 1.00 138.14 ? 144 ASP H OD2 1 ATOM 4425 N N . PHE C 2 162 ? 111.220 -24.219 35.719 1.00 133.57 ? 145 PHE H N 1 ATOM 4426 C CA . PHE C 2 162 ? 110.128 -23.246 35.632 1.00 132.71 ? 145 PHE H CA 1 ATOM 4427 C C . PHE C 2 162 ? 108.798 -23.829 35.161 1.00 132.14 ? 145 PHE H C 1 ATOM 4428 O O . PHE C 2 162 ? 108.761 -24.726 34.314 1.00 131.43 ? 145 PHE H O 1 ATOM 4429 C CB . PHE C 2 162 ? 110.536 -22.051 34.755 1.00 132.30 ? 145 PHE H CB 1 ATOM 4430 C CG . PHE C 2 162 ? 110.689 -22.373 33.298 1.00 131.78 ? 145 PHE H CG 1 ATOM 4431 C CD1 . PHE C 2 162 ? 109.579 -22.461 32.470 1.00 131.91 ? 145 PHE H CD1 1 ATOM 4432 C CD2 . PHE C 2 162 ? 111.949 -22.559 32.745 1.00 131.77 ? 145 PHE H CD2 1 ATOM 4433 C CE1 . PHE C 2 162 ? 109.721 -22.727 31.112 1.00 131.89 ? 145 PHE H CE1 1 ATOM 4434 C CE2 . PHE C 2 162 ? 112.102 -22.826 31.387 1.00 131.71 ? 145 PHE H CE2 1 ATOM 4435 C CZ . PHE C 2 162 ? 110.986 -22.909 30.570 1.00 131.67 ? 145 PHE H CZ 1 ATOM 4436 N N . LEU C 2 163 ? 107.710 -23.302 35.727 1.00 131.87 ? 146 LEU H N 1 ATOM 4437 C CA . LEU C 2 163 ? 106.353 -23.758 35.418 1.00 131.67 ? 146 LEU H CA 1 ATOM 4438 C C . LEU C 2 163 ? 105.567 -22.828 34.477 1.00 131.01 ? 146 LEU H C 1 ATOM 4439 O O . LEU C 2 163 ? 105.212 -23.227 33.363 1.00 131.73 ? 146 LEU H O 1 ATOM 4440 C CB . LEU C 2 163 ? 105.577 -23.976 36.729 1.00 131.75 ? 146 LEU H CB 1 ATOM 4441 C CG . LEU C 2 163 ? 104.203 -24.659 36.718 1.00 131.59 ? 146 LEU H CG 1 ATOM 4442 C CD1 . LEU C 2 163 ? 103.785 -24.967 38.152 1.00 131.31 ? 146 LEU H CD1 1 ATOM 4443 C CD2 . LEU C 2 163 ? 103.171 -23.773 36.041 1.00 131.37 ? 146 LEU H CD2 1 ATOM 4444 N N . PRO C 2 164 ? 105.272 -21.585 34.908 1.00 129.32 ? 147 PRO H N 1 ATOM 4445 C CA . PRO C 2 164 ? 104.523 -20.703 34.003 1.00 127.20 ? 147 PRO H CA 1 ATOM 4446 C C . PRO C 2 164 ? 105.377 -20.231 32.821 1.00 125.17 ? 147 PRO H C 1 ATOM 4447 O O . PRO C 2 164 ? 106.086 -19.230 32.921 1.00 124.78 ? 147 PRO H O 1 ATOM 4448 C CB . PRO C 2 164 ? 104.099 -19.559 34.919 1.00 127.35 ? 147 PRO H CB 1 ATOM 4449 C CG . PRO C 2 164 ? 105.248 -19.462 35.868 1.00 128.48 ? 147 PRO H CG 1 ATOM 4450 C CD . PRO C 2 164 ? 105.548 -20.911 36.191 1.00 128.82 ? 147 PRO H CD 1 ATOM 4451 N N . ASP C 2 165 ? 105.301 -20.959 31.708 1.00 122.74 ? 148 ASP H N 1 ATOM 4452 C CA . ASP C 2 165 ? 106.073 -20.633 30.511 1.00 120.90 ? 148 ASP H CA 1 ATOM 4453 C C . ASP C 2 165 ? 106.006 -19.166 30.131 1.00 120.83 ? 148 ASP H C 1 ATOM 4454 O O . ASP C 2 165 ? 104.924 -18.602 29.999 1.00 121.69 ? 148 ASP H O 1 ATOM 4455 C CB . ASP C 2 165 ? 105.595 -21.465 29.324 1.00 118.96 ? 148 ASP H CB 1 ATOM 4456 C CG . ASP C 2 165 ? 106.344 -21.142 28.044 1.00 117.96 ? 148 ASP H CG 1 ATOM 4457 O OD1 . ASP C 2 165 ? 106.148 -21.861 27.043 1.00 117.41 ? 148 ASP H OD1 1 ATOM 4458 O OD2 . ASP C 2 165 ? 107.127 -20.170 28.031 1.00 116.57 ? 148 ASP H OD2 1 ATOM 4459 N N . SER C 2 166 ? 107.175 -18.564 29.938 1.00 120.37 ? 149 SER H N 1 ATOM 4460 C CA . SER C 2 166 ? 107.285 -17.160 29.561 1.00 120.13 ? 149 SER H CA 1 ATOM 4461 C C . SER C 2 166 ? 108.732 -16.739 29.809 1.00 120.82 ? 149 SER H C 1 ATOM 4462 O O . SER C 2 166 ? 109.022 -15.975 30.729 1.00 120.80 ? 149 SER H O 1 ATOM 4463 C CB . SER C 2 166 ? 106.329 -16.302 30.400 1.00 118.95 ? 149 SER H CB 1 ATOM 4464 O OG . SER C 2 166 ? 106.016 -15.085 29.746 1.00 117.19 ? 149 SER H OG 1 ATOM 4465 N N . ILE C 2 167 ? 109.636 -17.250 28.980 1.00 121.53 ? 150 ILE H N 1 ATOM 4466 C CA . ILE C 2 167 ? 111.058 -16.954 29.109 1.00 122.41 ? 150 ILE H CA 1 ATOM 4467 C C . ILE C 2 167 ? 111.636 -16.149 27.943 1.00 123.50 ? 150 ILE H C 1 ATOM 4468 O O . ILE C 2 167 ? 111.978 -16.705 26.903 1.00 123.25 ? 150 ILE H O 1 ATOM 4469 C CB . ILE C 2 167 ? 111.860 -18.266 29.281 1.00 121.91 ? 150 ILE H CB 1 ATOM 4470 C CG1 . ILE C 2 167 ? 111.122 -19.433 28.614 1.00 121.50 ? 150 ILE H CG1 1 ATOM 4471 C CG2 . ILE C 2 167 ? 112.032 -18.579 30.757 1.00 121.98 ? 150 ILE H CG2 1 ATOM 4472 C CD1 . ILE C 2 167 ? 110.909 -19.281 27.127 1.00 121.20 ? 150 ILE H CD1 1 ATOM 4473 N N . THR C 2 168 ? 111.753 -14.836 28.132 1.00 125.49 ? 151 THR H N 1 ATOM 4474 C CA . THR C 2 168 ? 112.282 -13.938 27.102 1.00 127.38 ? 151 THR H CA 1 ATOM 4475 C C . THR C 2 168 ? 113.758 -14.193 26.804 1.00 128.65 ? 151 THR H C 1 ATOM 4476 O O . THR C 2 168 ? 114.634 -13.463 27.270 1.00 128.87 ? 151 THR H O 1 ATOM 4477 C CB . THR C 2 168 ? 112.125 -12.449 27.508 1.00 127.38 ? 151 THR H CB 1 ATOM 4478 O OG1 . THR C 2 168 ? 110.749 -12.167 27.795 1.00 127.63 ? 151 THR H OG1 1 ATOM 4479 C CG2 . THR C 2 168 ? 112.600 -11.535 26.385 1.00 127.36 ? 151 THR H CG2 1 ATOM 4480 N N . PHE C 2 169 ? 114.027 -15.229 26.021 1.00 130.12 ? 152 PHE H N 1 ATOM 4481 C CA . PHE C 2 169 ? 115.393 -15.570 25.656 1.00 131.77 ? 152 PHE H CA 1 ATOM 4482 C C . PHE C 2 169 ? 116.051 -14.467 24.833 1.00 133.82 ? 152 PHE H C 1 ATOM 4483 O O . PHE C 2 169 ? 115.378 -13.589 24.290 1.00 133.58 ? 152 PHE H O 1 ATOM 4484 C CB . PHE C 2 169 ? 115.416 -16.881 24.866 1.00 130.59 ? 152 PHE H CB 1 ATOM 4485 C CG . PHE C 2 169 ? 115.438 -18.110 25.727 1.00 129.45 ? 152 PHE H CG 1 ATOM 4486 C CD1 . PHE C 2 169 ? 114.523 -18.275 26.760 1.00 129.13 ? 152 PHE H CD1 1 ATOM 4487 C CD2 . PHE C 2 169 ? 116.371 -19.112 25.497 1.00 128.78 ? 152 PHE H CD2 1 ATOM 4488 C CE1 . PHE C 2 169 ? 114.539 -19.422 27.550 1.00 128.78 ? 152 PHE H CE1 1 ATOM 4489 C CE2 . PHE C 2 169 ? 116.396 -20.262 26.279 1.00 128.64 ? 152 PHE H CE2 1 ATOM 4490 C CZ . PHE C 2 169 ? 115.478 -20.418 27.308 1.00 128.82 ? 152 PHE H CZ 1 ATOM 4491 N N . SER C 2 170 ? 117.377 -14.537 24.757 1.00 136.61 ? 153 SER H N 1 ATOM 4492 C CA . SER C 2 170 ? 118.205 -13.590 24.014 1.00 139.21 ? 153 SER H CA 1 ATOM 4493 C C . SER C 2 170 ? 119.663 -13.931 24.320 1.00 140.76 ? 153 SER H C 1 ATOM 4494 O O . SER C 2 170 ? 119.936 -14.795 25.153 1.00 141.22 ? 153 SER H O 1 ATOM 4495 C CB . SER C 2 170 ? 117.908 -12.152 24.445 1.00 139.54 ? 153 SER H CB 1 ATOM 4496 O OG . SER C 2 170 ? 118.676 -11.230 23.689 1.00 140.07 ? 153 SER H OG 1 ATOM 4497 N N . TRP C 2 171 ? 120.601 -13.263 23.658 1.00 142.49 ? 154 TRP H N 1 ATOM 4498 C CA . TRP C 2 171 ? 122.010 -13.551 23.899 1.00 144.23 ? 154 TRP H CA 1 ATOM 4499 C C . TRP C 2 171 ? 122.910 -12.324 23.955 1.00 145.08 ? 154 TRP H C 1 ATOM 4500 O O . TRP C 2 171 ? 122.563 -11.260 23.443 1.00 145.38 ? 154 TRP H O 1 ATOM 4501 C CB . TRP C 2 171 ? 122.529 -14.514 22.835 1.00 144.82 ? 154 TRP H CB 1 ATOM 4502 C CG . TRP C 2 171 ? 121.915 -15.869 22.908 1.00 145.74 ? 154 TRP H CG 1 ATOM 4503 C CD1 . TRP C 2 171 ? 120.639 -16.215 22.567 1.00 145.79 ? 154 TRP H CD1 1 ATOM 4504 C CD2 . TRP C 2 171 ? 122.546 -17.064 23.371 1.00 146.40 ? 154 TRP H CD2 1 ATOM 4505 N NE1 . TRP C 2 171 ? 120.436 -17.555 22.790 1.00 145.99 ? 154 TRP H NE1 1 ATOM 4506 C CE2 . TRP C 2 171 ? 121.591 -18.101 23.283 1.00 146.59 ? 154 TRP H CE2 1 ATOM 4507 C CE3 . TRP C 2 171 ? 123.828 -17.361 23.853 1.00 146.94 ? 154 TRP H CE3 1 ATOM 4508 C CZ2 . TRP C 2 171 ? 121.879 -19.416 23.660 1.00 147.20 ? 154 TRP H CZ2 1 ATOM 4509 C CZ3 . TRP C 2 171 ? 124.114 -18.669 24.228 1.00 147.42 ? 154 TRP H CZ3 1 ATOM 4510 C CH2 . TRP C 2 171 ? 123.143 -19.679 24.129 1.00 147.56 ? 154 TRP H CH2 1 ATOM 4511 N N . LYS C 2 172 ? 124.072 -12.485 24.583 1.00 145.84 ? 155 LYS H N 1 ATOM 4512 C CA . LYS C 2 172 ? 125.034 -11.397 24.715 1.00 146.58 ? 155 LYS H CA 1 ATOM 4513 C C . LYS C 2 172 ? 126.452 -11.916 24.507 1.00 147.45 ? 155 LYS H C 1 ATOM 4514 O O . LYS C 2 172 ? 126.915 -12.794 25.233 1.00 147.40 ? 155 LYS H O 1 ATOM 4515 C CB . LYS C 2 172 ? 124.919 -10.755 26.100 1.00 146.03 ? 155 LYS H CB 1 ATOM 4516 C CG . LYS C 2 172 ? 123.501 -10.362 26.488 1.00 145.66 ? 155 LYS H CG 1 ATOM 4517 C CD . LYS C 2 172 ? 122.924 -9.323 25.536 1.00 145.04 ? 155 LYS H CD 1 ATOM 4518 C CE . LYS C 2 172 ? 121.431 -9.130 25.760 1.00 144.73 ? 155 LYS H CE 1 ATOM 4519 N NZ . LYS C 2 172 ? 121.116 -8.687 27.144 1.00 144.36 ? 155 LYS H NZ 1 ATOM 4520 N N . TYR C 2 173 ? 127.134 -11.364 23.508 1.00 148.70 ? 156 TYR H N 1 ATOM 4521 C CA . TYR C 2 173 ? 128.504 -11.755 23.183 1.00 149.82 ? 156 TYR H CA 1 ATOM 4522 C C . TYR C 2 173 ? 129.475 -11.571 24.345 1.00 150.17 ? 156 TYR H C 1 ATOM 4523 O O . TYR C 2 173 ? 129.068 -11.418 25.499 1.00 150.22 ? 156 TYR H O 1 ATOM 4524 C CB . TYR C 2 173 ? 129.009 -10.949 21.981 1.00 150.54 ? 156 TYR H CB 1 ATOM 4525 C CG . TYR C 2 173 ? 128.626 -11.502 20.621 1.00 151.25 ? 156 TYR H CG 1 ATOM 4526 C CD1 . TYR C 2 173 ? 128.789 -10.732 19.468 1.00 151.57 ? 156 TYR H CD1 1 ATOM 4527 C CD2 . TYR C 2 173 ? 128.127 -12.800 20.479 1.00 151.24 ? 156 TYR H CD2 1 ATOM 4528 C CE1 . TYR C 2 173 ? 128.465 -11.236 18.207 1.00 151.57 ? 156 TYR H CE1 1 ATOM 4529 C CE2 . TYR C 2 173 ? 127.800 -13.314 19.220 1.00 151.37 ? 156 TYR H CE2 1 ATOM 4530 C CZ . TYR C 2 173 ? 127.972 -12.525 18.092 1.00 151.57 ? 156 TYR H CZ 1 ATOM 4531 O OH . TYR C 2 173 ? 127.648 -13.016 16.848 1.00 151.57 ? 156 TYR H OH 1 ATOM 4532 N N . LYS C 2 174 ? 130.765 -11.584 24.021 1.00 150.46 ? 157 LYS H N 1 ATOM 4533 C CA . LYS C 2 174 ? 131.821 -11.422 25.013 1.00 150.82 ? 157 LYS H CA 1 ATOM 4534 C C . LYS C 2 174 ? 131.712 -10.075 25.719 1.00 151.03 ? 157 LYS H C 1 ATOM 4535 O O . LYS C 2 174 ? 131.224 -9.992 26.849 1.00 150.94 ? 157 LYS H O 1 ATOM 4536 C CB . LYS C 2 174 ? 133.194 -11.554 24.339 1.00 150.51 ? 157 LYS H CB 1 ATOM 4537 C CG . LYS C 2 174 ? 134.394 -11.527 25.290 1.00 150.21 ? 157 LYS H CG 1 ATOM 4538 C CD . LYS C 2 174 ? 134.756 -10.115 25.738 1.00 149.91 ? 157 LYS H CD 1 ATOM 4539 C CE . LYS C 2 174 ? 135.954 -10.121 26.677 1.00 149.94 ? 157 LYS H CE 1 ATOM 4540 N NZ . LYS C 2 174 ? 136.325 -8.753 27.136 1.00 149.41 ? 157 LYS H NZ 1 ATOM 4541 N N . ASN C 2 175 ? 132.162 -9.022 25.045 1.00 151.19 ? 158 ASN H N 1 ATOM 4542 C CA . ASN C 2 175 ? 132.133 -7.680 25.612 1.00 151.42 ? 158 ASN H CA 1 ATOM 4543 C C . ASN C 2 175 ? 130.726 -7.105 25.705 1.00 151.46 ? 158 ASN H C 1 ATOM 4544 O O . ASN C 2 175 ? 130.514 -5.922 25.438 1.00 151.56 ? 158 ASN H O 1 ATOM 4545 C CB . ASN C 2 175 ? 133.017 -6.744 24.786 1.00 151.44 ? 158 ASN H CB 1 ATOM 4546 C CG . ASN C 2 175 ? 132.581 -6.658 23.340 1.00 151.57 ? 158 ASN H CG 1 ATOM 4547 O OD1 . ASN C 2 175 ? 131.466 -6.232 23.038 1.00 151.57 ? 158 ASN H OD1 1 ATOM 4548 N ND2 . ASN C 2 175 ? 133.459 -7.068 22.434 1.00 151.57 ? 158 ASN H ND2 1 ATOM 4549 N N . ASN C 2 176 ? 129.767 -7.943 26.088 1.00 151.57 ? 159 ASN H N 1 ATOM 4550 C CA . ASN C 2 176 ? 128.380 -7.509 26.228 1.00 151.57 ? 159 ASN H CA 1 ATOM 4551 C C . ASN C 2 176 ? 127.883 -6.871 24.927 1.00 151.57 ? 159 ASN H C 1 ATOM 4552 O O . ASN C 2 176 ? 127.812 -5.645 24.812 1.00 151.57 ? 159 ASN H O 1 ATOM 4553 C CB . ASN C 2 176 ? 128.272 -6.515 27.397 1.00 151.21 ? 159 ASN H CB 1 ATOM 4554 C CG . ASN C 2 176 ? 126.834 -6.190 27.772 1.00 150.72 ? 159 ASN H CG 1 ATOM 4555 O OD1 . ASN C 2 176 ? 126.103 -5.560 27.006 1.00 150.45 ? 159 ASN H OD1 1 ATOM 4556 N ND2 . ASN C 2 176 ? 126.424 -6.619 28.961 1.00 150.08 ? 159 ASN H ND2 1 ATOM 4557 N N . SER C 2 177 ? 127.546 -7.714 23.950 1.00 151.53 ? 160 SER H N 1 ATOM 4558 C CA . SER C 2 177 ? 127.052 -7.253 22.651 1.00 151.05 ? 160 SER H CA 1 ATOM 4559 C C . SER C 2 177 ? 125.749 -7.954 22.253 1.00 150.55 ? 160 SER H C 1 ATOM 4560 O O . SER C 2 177 ? 125.456 -9.058 22.721 1.00 150.61 ? 160 SER H O 1 ATOM 4561 C CB . SER C 2 177 ? 128.110 -7.491 21.566 1.00 150.87 ? 160 SER H CB 1 ATOM 4562 O OG . SER C 2 177 ? 129.300 -6.774 21.843 1.00 150.36 ? 160 SER H OG 1 ATOM 4563 N N . ASP C 2 178 ? 124.972 -7.309 21.387 1.00 149.66 ? 161 ASP H N 1 ATOM 4564 C CA . ASP C 2 178 ? 123.705 -7.870 20.930 1.00 148.60 ? 161 ASP H CA 1 ATOM 4565 C C . ASP C 2 178 ? 123.888 -8.766 19.711 1.00 148.00 ? 161 ASP H C 1 ATOM 4566 O O . ASP C 2 178 ? 124.195 -8.291 18.616 1.00 147.62 ? 161 ASP H O 1 ATOM 4567 C CB . ASP C 2 178 ? 122.715 -6.752 20.600 1.00 148.27 ? 161 ASP H CB 1 ATOM 4568 C CG . ASP C 2 178 ? 122.304 -5.960 21.822 1.00 148.05 ? 161 ASP H CG 1 ATOM 4569 O OD1 . ASP C 2 178 ? 123.172 -5.286 22.414 1.00 148.05 ? 161 ASP H OD1 1 ATOM 4570 O OD2 . ASP C 2 178 ? 121.114 -6.017 22.195 1.00 147.91 ? 161 ASP H OD2 1 ATOM 4571 N N . ILE C 2 179 ? 123.690 -10.065 19.913 1.00 147.35 ? 162 ILE H N 1 ATOM 4572 C CA . ILE C 2 179 ? 123.829 -11.044 18.844 1.00 146.62 ? 162 ILE H CA 1 ATOM 4573 C C . ILE C 2 179 ? 122.666 -10.931 17.869 1.00 145.89 ? 162 ILE H C 1 ATOM 4574 O O . ILE C 2 179 ? 121.515 -11.174 18.234 1.00 145.81 ? 162 ILE H O 1 ATOM 4575 C CB . ILE C 2 179 ? 123.855 -12.485 19.403 1.00 146.82 ? 162 ILE H CB 1 ATOM 4576 C CG1 . ILE C 2 179 ? 124.883 -12.581 20.532 1.00 146.98 ? 162 ILE H CG1 1 ATOM 4577 C CG2 . ILE C 2 179 ? 124.177 -13.473 18.287 1.00 146.48 ? 162 ILE H CG2 1 ATOM 4578 C CD1 . ILE C 2 179 ? 125.077 -13.978 21.084 1.00 146.88 ? 162 ILE H CD1 1 ATOM 4579 N N . SER C 2 180 ? 122.970 -10.562 16.629 1.00 144.88 ? 163 SER H N 1 ATOM 4580 C CA . SER C 2 180 ? 121.941 -10.428 15.606 1.00 144.12 ? 163 SER H CA 1 ATOM 4581 C C . SER C 2 180 ? 121.321 -11.787 15.303 1.00 143.61 ? 163 SER H C 1 ATOM 4582 O O . SER C 2 180 ? 120.659 -11.970 14.280 1.00 143.71 ? 163 SER H O 1 ATOM 4583 C CB . SER C 2 180 ? 122.539 -9.833 14.330 1.00 143.93 ? 163 SER H CB 1 ATOM 4584 O OG . SER C 2 180 ? 123.019 -8.522 14.563 1.00 143.90 ? 163 SER H OG 1 ATOM 4585 N N . SER C 2 181 ? 121.541 -12.739 16.204 1.00 142.61 ? 164 SER H N 1 ATOM 4586 C CA . SER C 2 181 ? 121.009 -14.082 16.047 1.00 141.59 ? 164 SER H CA 1 ATOM 4587 C C . SER C 2 181 ? 120.371 -14.561 17.348 1.00 140.94 ? 164 SER H C 1 ATOM 4588 O O . SER C 2 181 ? 120.996 -14.528 18.409 1.00 140.83 ? 164 SER H O 1 ATOM 4589 C CB . SER C 2 181 ? 122.126 -15.040 15.630 1.00 141.38 ? 164 SER H CB 1 ATOM 4590 O OG . SER C 2 181 ? 121.618 -16.340 15.400 1.00 141.11 ? 164 SER H OG 1 ATOM 4591 N N . THR C 2 182 ? 119.117 -14.995 17.251 1.00 140.04 ? 165 THR H N 1 ATOM 4592 C CA . THR C 2 182 ? 118.363 -15.495 18.398 1.00 138.75 ? 165 THR H CA 1 ATOM 4593 C C . THR C 2 182 ? 117.275 -16.453 17.915 1.00 137.80 ? 165 THR H C 1 ATOM 4594 O O . THR C 2 182 ? 116.885 -16.419 16.746 1.00 137.93 ? 165 THR H O 1 ATOM 4595 C CB . THR C 2 182 ? 117.685 -14.346 19.177 1.00 138.85 ? 165 THR H CB 1 ATOM 4596 O OG1 . THR C 2 182 ? 116.881 -13.570 18.279 1.00 138.72 ? 165 THR H OG1 1 ATOM 4597 C CG2 . THR C 2 182 ? 118.727 -13.452 19.838 1.00 138.55 ? 165 THR H CG2 1 ATOM 4598 N N . ARG C 2 183 ? 116.792 -17.306 18.816 1.00 136.41 ? 166 ARG H N 1 ATOM 4599 C CA . ARG C 2 183 ? 115.743 -18.270 18.487 1.00 134.47 ? 166 ARG H CA 1 ATOM 4600 C C . ARG C 2 183 ? 114.891 -18.626 19.696 1.00 132.60 ? 166 ARG H C 1 ATOM 4601 O O . ARG C 2 183 ? 115.359 -18.577 20.834 1.00 132.11 ? 166 ARG H O 1 ATOM 4602 C CB . ARG C 2 183 ? 116.343 -19.554 17.911 1.00 134.91 ? 166 ARG H CB 1 ATOM 4603 C CG . ARG C 2 183 ? 116.992 -19.388 16.553 1.00 135.45 ? 166 ARG H CG 1 ATOM 4604 C CD . ARG C 2 183 ? 117.040 -20.718 15.832 1.00 136.13 ? 166 ARG H CD 1 ATOM 4605 N NE . ARG C 2 183 ? 117.578 -20.594 14.482 1.00 136.79 ? 166 ARG H NE 1 ATOM 4606 C CZ . ARG C 2 183 ? 117.468 -21.535 13.549 1.00 137.07 ? 166 ARG H CZ 1 ATOM 4607 N NH1 . ARG C 2 183 ? 116.834 -22.669 13.824 1.00 136.90 ? 166 ARG H NH1 1 ATOM 4608 N NH2 . ARG C 2 183 ? 117.993 -21.345 12.345 1.00 137.18 ? 166 ARG H NH2 1 ATOM 4609 N N . GLY C 2 184 ? 113.639 -18.992 19.438 1.00 130.70 ? 167 GLY H N 1 ATOM 4610 C CA . GLY C 2 184 ? 112.733 -19.359 20.512 1.00 127.99 ? 167 GLY H CA 1 ATOM 4611 C C . GLY C 2 184 ? 112.015 -20.665 20.228 1.00 125.62 ? 167 GLY H C 1 ATOM 4612 O O . GLY C 2 184 ? 111.034 -20.692 19.484 1.00 125.62 ? 167 GLY H O 1 ATOM 4613 N N . PHE C 2 185 ? 112.500 -21.751 20.822 1.00 122.83 ? 168 PHE H N 1 ATOM 4614 C CA . PHE C 2 185 ? 111.896 -23.060 20.615 1.00 119.99 ? 168 PHE H CA 1 ATOM 4615 C C . PHE C 2 185 ? 110.727 -23.360 21.537 1.00 118.82 ? 168 PHE H C 1 ATOM 4616 O O . PHE C 2 185 ? 110.616 -22.803 22.629 1.00 117.79 ? 168 PHE H O 1 ATOM 4617 C CB . PHE C 2 185 ? 112.952 -24.158 20.742 1.00 118.74 ? 168 PHE H CB 1 ATOM 4618 C CG . PHE C 2 185 ? 113.796 -24.317 19.517 1.00 116.87 ? 168 PHE H CG 1 ATOM 4619 C CD1 . PHE C 2 185 ? 114.654 -23.300 19.111 1.00 116.09 ? 168 PHE H CD1 1 ATOM 4620 C CD2 . PHE C 2 185 ? 113.709 -25.471 18.746 1.00 115.64 ? 168 PHE H CD2 1 ATOM 4621 C CE1 . PHE C 2 185 ? 115.414 -23.428 17.954 1.00 115.68 ? 168 PHE H CE1 1 ATOM 4622 C CE2 . PHE C 2 185 ? 114.463 -25.609 17.588 1.00 115.27 ? 168 PHE H CE2 1 ATOM 4623 C CZ . PHE C 2 185 ? 115.319 -24.586 17.189 1.00 115.28 ? 168 PHE H CZ 1 ATOM 4624 N N . PRO C 2 186 ? 109.841 -24.269 21.105 1.00 118.42 ? 169 PRO H N 1 ATOM 4625 C CA . PRO C 2 186 ? 108.665 -24.654 21.881 1.00 118.03 ? 169 PRO H CA 1 ATOM 4626 C C . PRO C 2 186 ? 109.063 -25.257 23.207 1.00 117.42 ? 169 PRO H C 1 ATOM 4627 O O . PRO C 2 186 ? 109.943 -26.112 23.270 1.00 117.99 ? 169 PRO H O 1 ATOM 4628 C CB . PRO C 2 186 ? 107.977 -25.667 20.977 1.00 118.18 ? 169 PRO H CB 1 ATOM 4629 C CG . PRO C 2 186 ? 109.134 -26.361 20.354 1.00 118.53 ? 169 PRO H CG 1 ATOM 4630 C CD . PRO C 2 186 ? 110.033 -25.196 19.976 1.00 118.80 ? 169 PRO H CD 1 ATOM 4631 N N . SER C 2 187 ? 108.416 -24.799 24.267 1.00 116.50 ? 170 SER H N 1 ATOM 4632 C CA . SER C 2 187 ? 108.694 -25.307 25.595 1.00 115.56 ? 170 SER H CA 1 ATOM 4633 C C . SER C 2 187 ? 107.927 -26.615 25.755 1.00 115.83 ? 170 SER H C 1 ATOM 4634 O O . SER C 2 187 ? 106.806 -26.749 25.265 1.00 115.86 ? 170 SER H O 1 ATOM 4635 C CB . SER C 2 187 ? 108.249 -24.285 26.636 1.00 114.41 ? 170 SER H CB 1 ATOM 4636 O OG . SER C 2 187 ? 108.828 -23.023 26.358 1.00 112.38 ? 170 SER H OG 1 ATOM 4637 N N . VAL C 2 188 ? 108.541 -27.586 26.422 1.00 115.91 ? 171 VAL H N 1 ATOM 4638 C CA . VAL C 2 188 ? 107.902 -28.876 26.629 1.00 115.96 ? 171 VAL H CA 1 ATOM 4639 C C . VAL C 2 188 ? 107.634 -29.125 28.103 1.00 115.94 ? 171 VAL H C 1 ATOM 4640 O O . VAL C 2 188 ? 108.476 -28.857 28.961 1.00 115.87 ? 171 VAL H O 1 ATOM 4641 C CB . VAL C 2 188 ? 108.764 -30.024 26.074 1.00 116.38 ? 171 VAL H CB 1 ATOM 4642 C CG1 . VAL C 2 188 ? 110.133 -30.013 26.737 1.00 116.66 ? 171 VAL H CG1 1 ATOM 4643 C CG2 . VAL C 2 188 ? 108.061 -31.354 26.301 1.00 116.53 ? 171 VAL H CG2 1 ATOM 4644 N N . LEU C 2 189 ? 106.450 -29.648 28.386 1.00 116.33 ? 172 LEU H N 1 ATOM 4645 C CA . LEU C 2 189 ? 106.043 -29.922 29.751 1.00 117.01 ? 172 LEU H CA 1 ATOM 4646 C C . LEU C 2 189 ? 106.337 -31.362 30.149 1.00 117.69 ? 172 LEU H C 1 ATOM 4647 O O . LEU C 2 189 ? 105.754 -32.305 29.607 1.00 117.82 ? 172 LEU H O 1 ATOM 4648 C CB . LEU C 2 189 ? 104.546 -29.615 29.911 1.00 116.41 ? 172 LEU H CB 1 ATOM 4649 C CG . LEU C 2 189 ? 103.883 -29.730 31.288 1.00 116.33 ? 172 LEU H CG 1 ATOM 4650 C CD1 . LEU C 2 189 ? 102.559 -28.986 31.266 1.00 116.08 ? 172 LEU H CD1 1 ATOM 4651 C CD2 . LEU C 2 189 ? 103.674 -31.190 31.664 1.00 115.87 ? 172 LEU H CD2 1 ATOM 4652 N N . ARG C 2 190 ? 107.258 -31.520 31.096 1.00 118.14 ? 173 ARG H N 1 ATOM 4653 C CA . ARG C 2 190 ? 107.626 -32.835 31.604 1.00 118.14 ? 173 ARG H CA 1 ATOM 4654 C C . ARG C 2 190 ? 107.326 -32.836 33.103 1.00 117.67 ? 173 ARG H C 1 ATOM 4655 O O . ARG C 2 190 ? 108.036 -32.206 33.887 1.00 117.23 ? 173 ARG H O 1 ATOM 4656 C CB . ARG C 2 190 ? 109.117 -33.113 31.366 1.00 119.07 ? 173 ARG H CB 1 ATOM 4657 C CG . ARG C 2 190 ? 109.512 -34.591 31.484 1.00 120.08 ? 173 ARG H CG 1 ATOM 4658 C CD . ARG C 2 190 ? 111.030 -34.799 31.595 1.00 120.44 ? 173 ARG H CD 1 ATOM 4659 N NE . ARG C 2 190 ? 111.787 -34.146 30.525 1.00 120.57 ? 173 ARG H NE 1 ATOM 4660 C CZ . ARG C 2 190 ? 112.516 -33.040 30.679 1.00 120.35 ? 173 ARG H CZ 1 ATOM 4661 N NH1 . ARG C 2 190 ? 112.596 -32.446 31.865 1.00 120.21 ? 173 ARG H NH1 1 ATOM 4662 N NH2 . ARG C 2 190 ? 113.174 -32.528 29.646 1.00 119.39 ? 173 ARG H NH2 1 ATOM 4663 N N . GLY C 2 191 ? 106.254 -33.520 33.489 1.00 117.41 ? 174 GLY H N 1 ATOM 4664 C CA . GLY C 2 191 ? 105.884 -33.597 34.890 1.00 117.48 ? 174 GLY H CA 1 ATOM 4665 C C . GLY C 2 191 ? 105.465 -32.296 35.558 1.00 117.64 ? 174 GLY H C 1 ATOM 4666 O O . GLY C 2 191 ? 106.017 -31.922 36.593 1.00 117.65 ? 174 GLY H O 1 ATOM 4667 N N . GLY C 2 192 ? 104.489 -31.605 34.976 1.00 117.57 ? 175 GLY H N 1 ATOM 4668 C CA . GLY C 2 192 ? 104.013 -30.361 35.559 1.00 117.09 ? 175 GLY H CA 1 ATOM 4669 C C . GLY C 2 192 ? 105.029 -29.231 35.628 1.00 116.84 ? 175 GLY H C 1 ATOM 4670 O O . GLY C 2 192 ? 104.962 -28.380 36.519 1.00 116.89 ? 175 GLY H O 1 ATOM 4671 N N . LYS C 2 193 ? 105.972 -29.219 34.691 1.00 115.99 ? 176 LYS H N 1 ATOM 4672 C CA . LYS C 2 193 ? 106.998 -28.181 34.632 1.00 115.36 ? 176 LYS H CA 1 ATOM 4673 C C . LYS C 2 193 ? 107.477 -28.107 33.190 1.00 115.82 ? 176 LYS H C 1 ATOM 4674 O O . LYS C 2 193 ? 107.464 -29.111 32.479 1.00 115.87 ? 176 LYS H O 1 ATOM 4675 C CB . LYS C 2 193 ? 108.173 -28.531 35.550 1.00 114.16 ? 176 LYS H CB 1 ATOM 4676 C CG . LYS C 2 193 ? 107.822 -28.655 37.032 1.00 112.51 ? 176 LYS H CG 1 ATOM 4677 C CD . LYS C 2 193 ? 107.528 -27.308 37.681 1.00 110.10 ? 176 LYS H CD 1 ATOM 4678 C CE . LYS C 2 193 ? 107.291 -27.467 39.176 1.00 108.17 ? 176 LYS H CE 1 ATOM 4679 N NZ . LYS C 2 193 ? 107.185 -26.156 39.861 1.00 106.41 ? 176 LYS H NZ 1 ATOM 4680 N N . TYR C 2 194 ? 107.896 -26.927 32.748 1.00 116.40 ? 177 TYR H N 1 ATOM 4681 C CA . TYR C 2 194 ? 108.356 -26.783 31.373 1.00 117.53 ? 177 TYR H CA 1 ATOM 4682 C C . TYR C 2 194 ? 109.873 -26.687 31.323 1.00 117.95 ? 177 TYR H C 1 ATOM 4683 O O . TYR C 2 194 ? 110.531 -26.625 32.357 1.00 117.84 ? 177 TYR H O 1 ATOM 4684 C CB . TYR C 2 194 ? 107.755 -25.533 30.716 1.00 118.29 ? 177 TYR H CB 1 ATOM 4685 C CG . TYR C 2 194 ? 106.236 -25.427 30.722 1.00 118.60 ? 177 TYR H CG 1 ATOM 4686 C CD1 . TYR C 2 194 ? 105.592 -24.475 29.934 1.00 118.39 ? 177 TYR H CD1 1 ATOM 4687 C CD2 . TYR C 2 194 ? 105.447 -26.235 31.545 1.00 118.72 ? 177 TYR H CD2 1 ATOM 4688 C CE1 . TYR C 2 194 ? 104.209 -24.322 29.965 1.00 118.37 ? 177 TYR H CE1 1 ATOM 4689 C CE2 . TYR C 2 194 ? 104.059 -26.090 31.583 1.00 118.33 ? 177 TYR H CE2 1 ATOM 4690 C CZ . TYR C 2 194 ? 103.449 -25.131 30.792 1.00 118.43 ? 177 TYR H CZ 1 ATOM 4691 O OH . TYR C 2 194 ? 102.084 -24.966 30.837 1.00 117.85 ? 177 TYR H OH 1 ATOM 4692 N N . ALA C 2 195 ? 110.415 -26.667 30.110 1.00 119.10 ? 178 ALA H N 1 ATOM 4693 C CA . ALA C 2 195 ? 111.855 -26.577 29.898 1.00 120.45 ? 178 ALA H CA 1 ATOM 4694 C C . ALA C 2 195 ? 112.154 -26.468 28.405 1.00 121.34 ? 178 ALA H C 1 ATOM 4695 O O . ALA C 2 195 ? 111.950 -27.426 27.662 1.00 121.39 ? 178 ALA H O 1 ATOM 4696 C CB . ALA C 2 195 ? 112.535 -27.806 30.472 1.00 120.81 ? 178 ALA H CB 1 ATOM 4697 N N . ALA C 2 196 ? 112.639 -25.309 27.967 1.00 122.71 ? 179 ALA H N 1 ATOM 4698 C CA . ALA C 2 196 ? 112.945 -25.106 26.551 1.00 124.63 ? 179 ALA H CA 1 ATOM 4699 C C . ALA C 2 196 ? 114.406 -24.757 26.283 1.00 125.92 ? 179 ALA H C 1 ATOM 4700 O O . ALA C 2 196 ? 115.122 -24.292 27.170 1.00 126.15 ? 179 ALA H O 1 ATOM 4701 C CB . ALA C 2 196 ? 112.040 -24.024 25.974 1.00 124.75 ? 179 ALA H CB 1 ATOM 4702 N N . THR C 2 197 ? 114.837 -24.977 25.045 1.00 127.50 ? 180 THR H N 1 ATOM 4703 C CA . THR C 2 197 ? 116.213 -24.702 24.647 1.00 129.70 ? 180 THR H CA 1 ATOM 4704 C C . THR C 2 197 ? 116.286 -23.392 23.873 1.00 131.25 ? 180 THR H C 1 ATOM 4705 O O . THR C 2 197 ? 115.431 -22.523 24.036 1.00 131.59 ? 180 THR H O 1 ATOM 4706 C CB . THR C 2 197 ? 116.757 -25.827 23.748 1.00 129.55 ? 180 THR H CB 1 ATOM 4707 O OG1 . THR C 2 197 ? 116.277 -27.091 24.220 1.00 129.72 ? 180 THR H OG1 1 ATOM 4708 C CG2 . THR C 2 197 ? 118.275 -25.843 23.774 1.00 129.57 ? 180 THR H CG2 1 ATOM 4709 N N . SER C 2 198 ? 117.315 -23.261 23.037 1.00 133.34 ? 181 SER H N 1 ATOM 4710 C CA . SER C 2 198 ? 117.521 -22.076 22.203 1.00 135.61 ? 181 SER H CA 1 ATOM 4711 C C . SER C 2 198 ? 118.898 -22.089 21.545 1.00 136.61 ? 181 SER H C 1 ATOM 4712 O O . SER C 2 198 ? 119.911 -21.819 22.190 1.00 136.28 ? 181 SER H O 1 ATOM 4713 C CB . SER C 2 198 ? 117.358 -20.787 23.020 1.00 136.00 ? 181 SER H CB 1 ATOM 4714 O OG . SER C 2 198 ? 118.344 -20.675 24.031 1.00 136.58 ? 181 SER H OG 1 ATOM 4715 N N . GLN C 2 199 ? 118.925 -22.402 20.253 1.00 138.27 ? 182 GLN H N 1 ATOM 4716 C CA . GLN C 2 199 ? 120.173 -22.452 19.499 1.00 139.94 ? 182 GLN H CA 1 ATOM 4717 C C . GLN C 2 199 ? 120.438 -21.114 18.807 1.00 141.18 ? 182 GLN H C 1 ATOM 4718 O O . GLN C 2 199 ? 119.502 -20.412 18.419 1.00 141.63 ? 182 GLN H O 1 ATOM 4719 C CB . GLN C 2 199 ? 120.101 -23.565 18.454 1.00 139.50 ? 182 GLN H CB 1 ATOM 4720 C CG . GLN C 2 199 ? 121.402 -23.806 17.719 1.00 139.19 ? 182 GLN H CG 1 ATOM 4721 C CD . GLN C 2 199 ? 121.243 -24.782 16.578 1.00 139.01 ? 182 GLN H CD 1 ATOM 4722 O OE1 . GLN C 2 199 ? 120.593 -24.483 15.577 1.00 138.74 ? 182 GLN H OE1 1 ATOM 4723 N NE2 . GLN C 2 199 ? 121.831 -25.961 16.724 1.00 138.73 ? 182 GLN H NE2 1 ATOM 4724 N N . VAL C 2 200 ? 121.713 -20.764 18.654 1.00 142.08 ? 183 VAL H N 1 ATOM 4725 C CA . VAL C 2 200 ? 122.084 -19.511 18.005 1.00 143.07 ? 183 VAL H CA 1 ATOM 4726 C C . VAL C 2 200 ? 123.299 -19.684 17.101 1.00 144.25 ? 183 VAL H C 1 ATOM 4727 O O . VAL C 2 200 ? 124.438 -19.647 17.567 1.00 144.04 ? 183 VAL H O 1 ATOM 4728 C CB . VAL C 2 200 ? 122.399 -18.416 19.042 1.00 142.81 ? 183 VAL H CB 1 ATOM 4729 C CG1 . VAL C 2 200 ? 122.762 -17.119 18.336 1.00 142.59 ? 183 VAL H CG1 1 ATOM 4730 C CG2 . VAL C 2 200 ? 121.206 -18.206 19.946 1.00 142.67 ? 183 VAL H CG2 1 ATOM 4731 N N . LEU C 2 201 ? 123.043 -19.864 15.807 1.00 145.80 ? 184 LEU H N 1 ATOM 4732 C CA . LEU C 2 201 ? 124.102 -20.044 14.815 1.00 147.17 ? 184 LEU H CA 1 ATOM 4733 C C . LEU C 2 201 ? 125.142 -18.928 14.911 1.00 147.84 ? 184 LEU H C 1 ATOM 4734 O O . LEU C 2 201 ? 124.815 -17.792 15.258 1.00 147.97 ? 184 LEU H O 1 ATOM 4735 C CB . LEU C 2 201 ? 123.509 -20.073 13.398 1.00 147.25 ? 184 LEU H CB 1 ATOM 4736 C CG . LEU C 2 201 ? 122.432 -21.114 13.069 1.00 147.14 ? 184 LEU H CG 1 ATOM 4737 C CD1 . LEU C 2 201 ? 122.039 -20.992 11.605 1.00 146.91 ? 184 LEU H CD1 1 ATOM 4738 C CD2 . LEU C 2 201 ? 122.949 -22.513 13.359 1.00 147.46 ? 184 LEU H CD2 1 ATOM 4739 N N . LEU C 2 202 ? 126.393 -19.260 14.599 1.00 148.59 ? 185 LEU H N 1 ATOM 4740 C CA . LEU C 2 202 ? 127.484 -18.292 14.654 1.00 149.37 ? 185 LEU H CA 1 ATOM 4741 C C . LEU C 2 202 ? 128.547 -18.608 13.601 1.00 149.37 ? 185 LEU H C 1 ATOM 4742 O O . LEU C 2 202 ? 128.631 -19.738 13.117 1.00 149.15 ? 185 LEU H O 1 ATOM 4743 C CB . LEU C 2 202 ? 128.113 -18.303 16.052 1.00 150.24 ? 185 LEU H CB 1 ATOM 4744 C CG . LEU C 2 202 ? 127.162 -18.037 17.228 1.00 151.12 ? 185 LEU H CG 1 ATOM 4745 C CD1 . LEU C 2 202 ? 127.894 -18.265 18.541 1.00 151.16 ? 185 LEU H CD1 1 ATOM 4746 C CD2 . LEU C 2 202 ? 126.621 -16.612 17.153 1.00 151.57 ? 185 LEU H CD2 1 ATOM 4747 N N . PRO C 2 203 ? 129.368 -17.607 13.228 1.00 149.52 ? 186 PRO H N 1 ATOM 4748 C CA . PRO C 2 203 ? 130.435 -17.758 12.229 1.00 149.60 ? 186 PRO H CA 1 ATOM 4749 C C . PRO C 2 203 ? 131.429 -18.882 12.543 1.00 149.63 ? 186 PRO H C 1 ATOM 4750 O O . PRO C 2 203 ? 131.036 -20.000 12.879 1.00 149.70 ? 186 PRO H O 1 ATOM 4751 C CB . PRO C 2 203 ? 131.101 -16.382 12.231 1.00 149.49 ? 186 PRO H CB 1 ATOM 4752 C CG . PRO C 2 203 ? 129.960 -15.464 12.545 1.00 149.15 ? 186 PRO H CG 1 ATOM 4753 C CD . PRO C 2 203 ? 129.263 -16.202 13.665 1.00 149.29 ? 186 PRO H CD 1 ATOM 4754 N N . SER C 2 204 ? 132.718 -18.582 12.418 1.00 149.44 ? 187 SER H N 1 ATOM 4755 C CA . SER C 2 204 ? 133.759 -19.561 12.702 1.00 149.47 ? 187 SER H CA 1 ATOM 4756 C C . SER C 2 204 ? 134.632 -19.027 13.829 1.00 149.68 ? 187 SER H C 1 ATOM 4757 O O . SER C 2 204 ? 135.346 -19.787 14.484 1.00 149.88 ? 187 SER H O 1 ATOM 4758 C CB . SER C 2 204 ? 134.615 -19.815 11.459 1.00 149.34 ? 187 SER H CB 1 ATOM 4759 O OG . SER C 2 204 ? 135.325 -18.649 11.083 1.00 149.28 ? 187 SER H OG 1 ATOM 4760 N N . LYS C 2 205 ? 134.555 -17.713 14.036 1.00 149.58 ? 188 LYS H N 1 ATOM 4761 C CA . LYS C 2 205 ? 135.301 -16.994 15.073 1.00 149.35 ? 188 LYS H CA 1 ATOM 4762 C C . LYS C 2 205 ? 135.653 -15.603 14.550 1.00 149.83 ? 188 LYS H C 1 ATOM 4763 O O . LYS C 2 205 ? 136.826 -15.293 14.341 1.00 149.95 ? 188 LYS H O 1 ATOM 4764 C CB . LYS C 2 205 ? 136.590 -17.739 15.448 1.00 148.21 ? 188 LYS H CB 1 ATOM 4765 C CG . LYS C 2 205 ? 137.312 -17.182 16.668 1.00 146.79 ? 188 LYS H CG 1 ATOM 4766 C CD . LYS C 2 205 ? 138.562 -17.985 16.992 1.00 145.52 ? 188 LYS H CD 1 ATOM 4767 C CE . LYS C 2 205 ? 138.227 -19.423 17.344 1.00 144.64 ? 188 LYS H CE 1 ATOM 4768 N NZ . LYS C 2 205 ? 139.448 -20.222 17.625 1.00 143.94 ? 188 LYS H NZ 1 ATOM 4769 N N . ASP C 2 206 ? 134.639 -14.765 14.341 1.00 150.21 ? 189 ASP H N 1 ATOM 4770 C CA . ASP C 2 206 ? 134.868 -13.415 13.829 1.00 150.91 ? 189 ASP H CA 1 ATOM 4771 C C . ASP C 2 206 ? 133.960 -12.325 14.402 1.00 151.32 ? 189 ASP H C 1 ATOM 4772 O O . ASP C 2 206 ? 134.412 -11.483 15.181 1.00 151.51 ? 189 ASP H O 1 ATOM 4773 C CB . ASP C 2 206 ? 134.752 -13.418 12.304 1.00 150.91 ? 189 ASP H CB 1 ATOM 4774 C CG . ASP C 2 206 ? 135.931 -14.091 11.632 1.00 151.14 ? 189 ASP H CG 1 ATOM 4775 O OD1 . ASP C 2 206 ? 137.029 -13.492 11.615 1.00 150.58 ? 189 ASP H OD1 1 ATOM 4776 O OD2 . ASP C 2 206 ? 135.760 -15.221 11.129 1.00 151.48 ? 189 ASP H OD2 1 ATOM 4777 N N . VAL C 2 207 ? 132.688 -12.342 14.003 1.00 151.57 ? 190 VAL H N 1 ATOM 4778 C CA . VAL C 2 207 ? 131.694 -11.355 14.441 1.00 151.57 ? 190 VAL H CA 1 ATOM 4779 C C . VAL C 2 207 ? 132.241 -9.922 14.451 1.00 151.57 ? 190 VAL H C 1 ATOM 4780 O O . VAL C 2 207 ? 133.180 -9.605 13.718 1.00 151.49 ? 190 VAL H O 1 ATOM 4781 C CB . VAL C 2 207 ? 131.114 -11.702 15.849 1.00 151.57 ? 190 VAL H CB 1 ATOM 4782 C CG1 . VAL C 2 207 ? 130.477 -13.083 15.818 1.00 151.22 ? 190 VAL H CG1 1 ATOM 4783 C CG2 . VAL C 2 207 ? 132.201 -11.636 16.914 1.00 151.32 ? 190 VAL H CG2 1 ATOM 4784 N N . MET C 2 208 ? 131.647 -9.058 15.270 1.00 151.56 ? 191 MET H N 1 ATOM 4785 C CA . MET C 2 208 ? 132.088 -7.668 15.358 1.00 151.51 ? 191 MET H CA 1 ATOM 4786 C C . MET C 2 208 ? 132.665 -7.346 16.734 1.00 151.57 ? 191 MET H C 1 ATOM 4787 O O . MET C 2 208 ? 133.747 -6.765 16.844 1.00 151.23 ? 191 MET H O 1 ATOM 4788 C CB . MET C 2 208 ? 130.921 -6.718 15.076 1.00 151.37 ? 191 MET H CB 1 ATOM 4789 C CG . MET C 2 208 ? 129.837 -6.739 16.145 1.00 151.35 ? 191 MET H CG 1 ATOM 4790 S SD . MET C 2 208 ? 128.668 -5.375 15.998 1.00 151.57 ? 191 MET H SD 1 ATOM 4791 C CE . MET C 2 208 ? 129.576 -4.050 16.787 1.00 150.95 ? 191 MET H CE 1 ATOM 4792 N N . GLN C 2 209 ? 131.928 -7.724 17.777 1.00 151.57 ? 192 GLN H N 1 ATOM 4793 C CA . GLN C 2 209 ? 132.332 -7.481 19.159 1.00 151.57 ? 192 GLN H CA 1 ATOM 4794 C C . GLN C 2 209 ? 132.246 -8.751 20.007 1.00 151.57 ? 192 GLN H C 1 ATOM 4795 O O . GLN C 2 209 ? 131.702 -8.738 21.113 1.00 151.57 ? 192 GLN H O 1 ATOM 4796 C CB . GLN C 2 209 ? 131.450 -6.389 19.777 1.00 151.31 ? 192 GLN H CB 1 ATOM 4797 C CG . GLN C 2 209 ? 131.687 -5.000 19.203 1.00 150.85 ? 192 GLN H CG 1 ATOM 4798 C CD . GLN C 2 209 ? 132.967 -4.363 19.713 1.00 150.63 ? 192 GLN H CD 1 ATOM 4799 O OE1 . GLN C 2 209 ? 133.416 -3.345 19.189 1.00 150.65 ? 192 GLN H OE1 1 ATOM 4800 N NE2 . GLN C 2 209 ? 133.555 -4.954 20.747 1.00 150.31 ? 192 GLN H NE2 1 ATOM 4801 N N . GLY C 2 210 ? 132.789 -9.844 19.481 1.00 151.56 ? 193 GLY H N 1 ATOM 4802 C CA . GLY C 2 210 ? 132.765 -11.100 20.206 1.00 151.51 ? 193 GLY H CA 1 ATOM 4803 C C . GLY C 2 210 ? 134.121 -11.776 20.228 1.00 151.55 ? 193 GLY H C 1 ATOM 4804 O O . GLY C 2 210 ? 134.547 -12.352 19.225 1.00 151.27 ? 193 GLY H O 1 ATOM 4805 N N . THR C 2 211 ? 134.802 -11.701 21.370 1.00 151.57 ? 194 THR H N 1 ATOM 4806 C CA . THR C 2 211 ? 136.118 -12.317 21.521 1.00 151.57 ? 194 THR H CA 1 ATOM 4807 C C . THR C 2 211 ? 135.983 -13.832 21.364 1.00 151.57 ? 194 THR H C 1 ATOM 4808 O O . THR C 2 211 ? 135.857 -14.329 20.244 1.00 151.57 ? 194 THR H O 1 ATOM 4809 C CB . THR C 2 211 ? 136.746 -11.992 22.902 1.00 151.39 ? 194 THR H CB 1 ATOM 4810 O OG1 . THR C 2 211 ? 136.815 -10.571 23.078 1.00 151.25 ? 194 THR H OG1 1 ATOM 4811 C CG2 . THR C 2 211 ? 138.154 -12.564 22.998 1.00 151.14 ? 194 THR H CG2 1 ATOM 4812 N N . ASP C 2 212 ? 135.996 -14.564 22.477 1.00 151.57 ? 195 ASP H N 1 ATOM 4813 C CA . ASP C 2 212 ? 135.870 -16.019 22.421 1.00 151.57 ? 195 ASP H CA 1 ATOM 4814 C C . ASP C 2 212 ? 135.570 -16.681 23.765 1.00 151.50 ? 195 ASP H C 1 ATOM 4815 O O . ASP C 2 212 ? 135.148 -17.838 23.809 1.00 151.50 ? 195 ASP H O 1 ATOM 4816 C CB . ASP C 2 212 ? 137.135 -16.632 21.809 1.00 151.57 ? 195 ASP H CB 1 ATOM 4817 C CG . ASP C 2 212 ? 138.403 -15.960 22.296 1.00 151.57 ? 195 ASP H CG 1 ATOM 4818 O OD1 . ASP C 2 212 ? 138.615 -15.908 23.526 1.00 151.57 ? 195 ASP H OD1 1 ATOM 4819 O OD2 . ASP C 2 212 ? 139.187 -15.483 21.447 1.00 151.57 ? 195 ASP H OD2 1 ATOM 4820 N N . GLU C 2 213 ? 135.785 -15.954 24.858 1.00 151.55 ? 196 GLU H N 1 ATOM 4821 C CA . GLU C 2 213 ? 135.515 -16.494 26.188 1.00 151.49 ? 196 GLU H CA 1 ATOM 4822 C C . GLU C 2 213 ? 134.011 -16.628 26.426 1.00 151.34 ? 196 GLU H C 1 ATOM 4823 O O . GLU C 2 213 ? 133.389 -15.736 27.008 1.00 151.49 ? 196 GLU H O 1 ATOM 4824 C CB . GLU C 2 213 ? 136.122 -15.594 27.273 1.00 151.40 ? 196 GLU H CB 1 ATOM 4825 C CG . GLU C 2 213 ? 137.552 -15.944 27.682 1.00 151.13 ? 196 GLU H CG 1 ATOM 4826 C CD . GLU C 2 213 ? 138.567 -15.697 26.584 1.00 150.84 ? 196 GLU H CD 1 ATOM 4827 O OE1 . GLU C 2 213 ? 138.721 -14.531 26.161 1.00 150.86 ? 196 GLU H OE1 1 ATOM 4828 O OE2 . GLU C 2 213 ? 139.213 -16.671 26.147 1.00 150.62 ? 196 GLU H OE2 1 ATOM 4829 N N . HIS C 2 214 ? 133.440 -17.747 25.983 1.00 150.72 ? 197 HIS H N 1 ATOM 4830 C CA . HIS C 2 214 ? 132.010 -18.029 26.131 1.00 150.17 ? 197 HIS H CA 1 ATOM 4831 C C . HIS C 2 214 ? 131.092 -16.839 25.828 1.00 149.80 ? 197 HIS H C 1 ATOM 4832 O O . HIS C 2 214 ? 131.542 -15.810 25.323 1.00 150.11 ? 197 HIS H O 1 ATOM 4833 C CB . HIS C 2 214 ? 131.718 -18.565 27.541 1.00 149.98 ? 197 HIS H CB 1 ATOM 4834 C CG . HIS C 2 214 ? 132.316 -17.744 28.640 1.00 149.45 ? 197 HIS H CG 1 ATOM 4835 N ND1 . HIS C 2 214 ? 133.664 -17.757 28.929 1.00 149.20 ? 197 HIS H ND1 1 ATOM 4836 C CD2 . HIS C 2 214 ? 131.756 -16.860 29.500 1.00 149.23 ? 197 HIS H CD2 1 ATOM 4837 C CE1 . HIS C 2 214 ? 133.908 -16.917 29.919 1.00 149.39 ? 197 HIS H CE1 1 ATOM 4838 N NE2 . HIS C 2 214 ? 132.767 -16.360 30.283 1.00 149.28 ? 197 HIS H NE2 1 ATOM 4839 N N . VAL C 2 215 ? 129.803 -16.989 26.126 1.00 148.95 ? 198 VAL H N 1 ATOM 4840 C CA . VAL C 2 215 ? 128.827 -15.926 25.879 1.00 147.93 ? 198 VAL H CA 1 ATOM 4841 C C . VAL C 2 215 ? 127.785 -15.812 26.991 1.00 147.40 ? 198 VAL H C 1 ATOM 4842 O O . VAL C 2 215 ? 127.856 -16.522 27.994 1.00 147.00 ? 198 VAL H O 1 ATOM 4843 C CB . VAL C 2 215 ? 128.091 -16.143 24.539 1.00 147.72 ? 198 VAL H CB 1 ATOM 4844 C CG1 . VAL C 2 215 ? 129.055 -15.963 23.381 1.00 147.22 ? 198 VAL H CG1 1 ATOM 4845 C CG2 . VAL C 2 215 ? 127.475 -17.533 24.505 1.00 147.35 ? 198 VAL H CG2 1 ATOM 4846 N N . VAL C 2 216 ? 126.817 -14.916 26.799 1.00 147.05 ? 199 VAL H N 1 ATOM 4847 C CA . VAL C 2 216 ? 125.754 -14.691 27.783 1.00 146.39 ? 199 VAL H CA 1 ATOM 4848 C C . VAL C 2 216 ? 124.400 -15.249 27.335 1.00 145.59 ? 199 VAL H C 1 ATOM 4849 O O . VAL C 2 216 ? 124.028 -15.157 26.163 1.00 145.45 ? 199 VAL H O 1 ATOM 4850 C CB . VAL C 2 216 ? 125.568 -13.180 28.083 1.00 146.42 ? 199 VAL H CB 1 ATOM 4851 C CG1 . VAL C 2 216 ? 124.625 -12.994 29.262 1.00 145.94 ? 199 VAL H CG1 1 ATOM 4852 C CG2 . VAL C 2 216 ? 126.911 -12.528 28.362 1.00 146.64 ? 199 VAL H CG2 1 ATOM 4853 N N . CYS C 2 217 ? 123.668 -15.818 28.288 1.00 144.40 ? 200 CYS H N 1 ATOM 4854 C CA . CYS C 2 217 ? 122.352 -16.392 28.029 1.00 143.17 ? 200 CYS H CA 1 ATOM 4855 C C . CYS C 2 217 ? 121.320 -15.671 28.899 1.00 142.38 ? 200 CYS H C 1 ATOM 4856 O O . CYS C 2 217 ? 121.018 -16.111 30.007 1.00 142.53 ? 200 CYS H O 1 ATOM 4857 C CB . CYS C 2 217 ? 122.373 -17.893 28.358 1.00 142.83 ? 200 CYS H CB 1 ATOM 4858 S SG . CYS C 2 217 ? 120.788 -18.795 28.239 1.00 142.29 ? 200 CYS H SG 1 ATOM 4859 N N . LYS C 2 218 ? 120.794 -14.555 28.400 1.00 141.22 ? 201 LYS H N 1 ATOM 4860 C CA . LYS C 2 218 ? 119.796 -13.784 29.139 1.00 140.19 ? 201 LYS H CA 1 ATOM 4861 C C . LYS C 2 218 ? 118.444 -14.485 29.077 1.00 139.72 ? 201 LYS H C 1 ATOM 4862 O O . LYS C 2 218 ? 117.818 -14.555 28.020 1.00 139.72 ? 201 LYS H O 1 ATOM 4863 C CB . LYS C 2 218 ? 119.659 -12.375 28.552 1.00 139.80 ? 201 LYS H CB 1 ATOM 4864 C CG . LYS C 2 218 ? 120.940 -11.555 28.550 1.00 139.82 ? 201 LYS H CG 1 ATOM 4865 C CD . LYS C 2 218 ? 121.454 -11.313 29.957 1.00 139.21 ? 201 LYS H CD 1 ATOM 4866 C CE . LYS C 2 218 ? 122.714 -10.457 29.953 1.00 138.66 ? 201 LYS H CE 1 ATOM 4867 N NZ . LYS C 2 218 ? 122.460 -9.087 29.436 1.00 138.13 ? 201 LYS H NZ 1 ATOM 4868 N N . VAL C 2 219 ? 117.992 -15.000 30.215 1.00 139.11 ? 202 VAL H N 1 ATOM 4869 C CA . VAL C 2 219 ? 116.714 -15.697 30.275 1.00 138.56 ? 202 VAL H CA 1 ATOM 4870 C C . VAL C 2 219 ? 115.740 -15.020 31.240 1.00 138.14 ? 202 VAL H C 1 ATOM 4871 O O . VAL C 2 219 ? 115.874 -15.138 32.459 1.00 137.97 ? 202 VAL H O 1 ATOM 4872 C CB . VAL C 2 219 ? 116.918 -17.170 30.694 1.00 138.57 ? 202 VAL H CB 1 ATOM 4873 C CG1 . VAL C 2 219 ? 115.577 -17.867 30.853 1.00 138.93 ? 202 VAL H CG1 1 ATOM 4874 C CG2 . VAL C 2 219 ? 117.759 -17.885 29.649 1.00 138.10 ? 202 VAL H CG2 1 ATOM 4875 N N . GLN C 2 220 ? 114.760 -14.316 30.678 1.00 137.60 ? 203 GLN H N 1 ATOM 4876 C CA . GLN C 2 220 ? 113.746 -13.603 31.456 1.00 137.05 ? 203 GLN H CA 1 ATOM 4877 C C . GLN C 2 220 ? 112.657 -14.532 31.992 1.00 136.17 ? 203 GLN H C 1 ATOM 4878 O O . GLN C 2 220 ? 112.540 -15.680 31.562 1.00 136.77 ? 203 GLN H O 1 ATOM 4879 C CB . GLN C 2 220 ? 113.097 -12.517 30.594 1.00 137.50 ? 203 GLN H CB 1 ATOM 4880 C CG . GLN C 2 220 ? 114.060 -11.462 30.096 1.00 138.38 ? 203 GLN H CG 1 ATOM 4881 C CD . GLN C 2 220 ? 114.598 -10.608 31.221 1.00 139.27 ? 203 GLN H CD 1 ATOM 4882 O OE1 . GLN C 2 220 ? 113.847 -9.884 31.875 1.00 139.77 ? 203 GLN H OE1 1 ATOM 4883 N NE2 . GLN C 2 220 ? 115.903 -10.689 31.457 1.00 139.58 ? 203 GLN H NE2 1 ATOM 4884 N N . HIS C 2 221 ? 111.855 -14.022 32.924 1.00 134.54 ? 204 HIS H N 1 ATOM 4885 C CA . HIS C 2 221 ? 110.777 -14.801 33.523 1.00 132.75 ? 204 HIS H CA 1 ATOM 4886 C C . HIS C 2 221 ? 110.165 -14.007 34.677 1.00 132.17 ? 204 HIS H C 1 ATOM 4887 O O . HIS C 2 221 ? 110.871 -13.309 35.406 1.00 131.66 ? 204 HIS H O 1 ATOM 4888 C CB . HIS C 2 221 ? 111.326 -16.144 34.027 1.00 131.78 ? 204 HIS H CB 1 ATOM 4889 C CG . HIS C 2 221 ? 110.272 -17.134 34.422 1.00 130.52 ? 204 HIS H CG 1 ATOM 4890 N ND1 . HIS C 2 221 ? 109.458 -16.963 35.521 1.00 130.23 ? 204 HIS H ND1 1 ATOM 4891 C CD2 . HIS C 2 221 ? 109.924 -18.325 33.879 1.00 129.95 ? 204 HIS H CD2 1 ATOM 4892 C CE1 . HIS C 2 221 ? 108.656 -18.006 35.640 1.00 129.69 ? 204 HIS H CE1 1 ATOM 4893 N NE2 . HIS C 2 221 ? 108.919 -18.847 34.657 1.00 129.81 ? 204 HIS H NE2 1 ATOM 4894 N N . PRO C 2 222 ? 108.837 -14.090 34.842 1.00 131.82 ? 205 PRO H N 1 ATOM 4895 C CA . PRO C 2 222 ? 108.117 -13.385 35.907 1.00 131.48 ? 205 PRO H CA 1 ATOM 4896 C C . PRO C 2 222 ? 108.571 -13.763 37.317 1.00 130.85 ? 205 PRO H C 1 ATOM 4897 O O . PRO C 2 222 ? 108.459 -12.964 38.246 1.00 130.78 ? 205 PRO H O 1 ATOM 4898 C CB . PRO C 2 222 ? 106.664 -13.773 35.647 1.00 131.71 ? 205 PRO H CB 1 ATOM 4899 C CG . PRO C 2 222 ? 106.625 -13.897 34.160 1.00 131.69 ? 205 PRO H CG 1 ATOM 4900 C CD . PRO C 2 222 ? 107.887 -14.681 33.883 1.00 131.82 ? 205 PRO H CD 1 ATOM 4901 N N . ASN C 2 223 ? 109.081 -14.981 37.472 1.00 130.17 ? 206 ASN H N 1 ATOM 4902 C CA . ASN C 2 223 ? 109.536 -15.450 38.776 1.00 129.32 ? 206 ASN H CA 1 ATOM 4903 C C . ASN C 2 223 ? 111.058 -15.490 38.884 1.00 129.29 ? 206 ASN H C 1 ATOM 4904 O O . ASN C 2 223 ? 111.610 -16.291 39.639 1.00 128.93 ? 206 ASN H O 1 ATOM 4905 C CB . ASN C 2 223 ? 108.961 -16.839 39.055 1.00 128.13 ? 206 ASN H CB 1 ATOM 4906 C CG . ASN C 2 223 ? 107.457 -16.881 38.903 1.00 127.15 ? 206 ASN H CG 1 ATOM 4907 O OD1 . ASN C 2 223 ? 106.931 -16.738 37.801 1.00 127.04 ? 206 ASN H OD1 1 ATOM 4908 N ND2 . ASN C 2 223 ? 106.754 -17.066 40.012 1.00 126.57 ? 206 ASN H ND2 1 ATOM 4909 N N . GLY C 2 224 ? 111.729 -14.619 38.134 1.00 129.54 ? 207 GLY H N 1 ATOM 4910 C CA . GLY C 2 224 ? 113.181 -14.573 38.162 1.00 129.73 ? 207 GLY H CA 1 ATOM 4911 C C . GLY C 2 224 ? 113.806 -14.741 36.790 1.00 129.91 ? 207 GLY H C 1 ATOM 4912 O O . GLY C 2 224 ? 113.395 -15.602 36.016 1.00 129.63 ? 207 GLY H O 1 ATOM 4913 N N . ASN C 2 225 ? 114.812 -13.926 36.490 1.00 130.65 ? 208 ASN H N 1 ATOM 4914 C CA . ASN C 2 225 ? 115.486 -13.979 35.196 1.00 131.82 ? 208 ASN H CA 1 ATOM 4915 C C . ASN C 2 225 ? 116.912 -14.522 35.321 1.00 132.86 ? 208 ASN H C 1 ATOM 4916 O O . ASN C 2 225 ? 117.871 -13.750 35.388 1.00 133.48 ? 208 ASN H O 1 ATOM 4917 C CB . ASN C 2 225 ? 115.531 -12.578 34.581 1.00 131.33 ? 208 ASN H CB 1 ATOM 4918 C CG . ASN C 2 225 ? 114.318 -11.746 34.945 1.00 131.34 ? 208 ASN H CG 1 ATOM 4919 O OD1 . ASN C 2 225 ? 114.111 -11.411 36.111 1.00 131.38 ? 208 ASN H OD1 1 ATOM 4920 N ND2 . ASN C 2 225 ? 113.506 -11.413 33.950 1.00 131.31 ? 208 ASN H ND2 1 ATOM 4921 N N . LYS C 2 226 ? 117.046 -15.847 35.338 1.00 133.55 ? 209 LYS H N 1 ATOM 4922 C CA . LYS C 2 226 ? 118.352 -16.496 35.463 1.00 133.63 ? 209 LYS H CA 1 ATOM 4923 C C . LYS C 2 226 ? 119.214 -16.364 34.205 1.00 134.63 ? 209 LYS H C 1 ATOM 4924 O O . LYS C 2 226 ? 118.702 -16.379 33.085 1.00 134.96 ? 209 LYS H O 1 ATOM 4925 C CB . LYS C 2 226 ? 118.171 -17.979 35.808 1.00 132.42 ? 209 LYS H CB 1 ATOM 4926 C CG . LYS C 2 226 ? 117.387 -18.232 37.090 1.00 130.85 ? 209 LYS H CG 1 ATOM 4927 C CD . LYS C 2 226 ? 118.022 -17.531 38.281 1.00 129.72 ? 209 LYS H CD 1 ATOM 4928 C CE . LYS C 2 226 ? 117.259 -17.806 39.567 1.00 128.97 ? 209 LYS H CE 1 ATOM 4929 N NZ . LYS C 2 226 ? 117.300 -19.243 39.949 1.00 128.38 ? 209 LYS H NZ 1 ATOM 4930 N N . GLU C 2 227 ? 120.525 -16.238 34.405 1.00 135.65 ? 210 GLU H N 1 ATOM 4931 C CA . GLU C 2 227 ? 121.485 -16.102 33.309 1.00 136.32 ? 210 GLU H CA 1 ATOM 4932 C C . GLU C 2 227 ? 122.638 -17.086 33.470 1.00 136.14 ? 210 GLU H C 1 ATOM 4933 O O . GLU C 2 227 ? 122.994 -17.450 34.592 1.00 136.23 ? 210 GLU H O 1 ATOM 4934 C CB . GLU C 2 227 ? 122.070 -14.688 33.277 1.00 137.49 ? 210 GLU H CB 1 ATOM 4935 C CG . GLU C 2 227 ? 121.095 -13.583 32.919 1.00 139.61 ? 210 GLU H CG 1 ATOM 4936 C CD . GLU C 2 227 ? 121.740 -12.210 33.001 1.00 140.57 ? 210 GLU H CD 1 ATOM 4937 O OE1 . GLU C 2 227 ? 122.810 -12.021 32.378 1.00 140.56 ? 210 GLU H OE1 1 ATOM 4938 O OE2 . GLU C 2 227 ? 121.178 -11.325 33.686 1.00 141.08 ? 210 GLU H OE2 1 ATOM 4939 N N . LYS C 2 228 ? 123.224 -17.499 32.348 1.00 135.77 ? 211 LYS H N 1 ATOM 4940 C CA . LYS C 2 228 ? 124.355 -18.426 32.358 1.00 135.25 ? 211 LYS H CA 1 ATOM 4941 C C . LYS C 2 228 ? 125.232 -18.277 31.116 1.00 135.09 ? 211 LYS H C 1 ATOM 4942 O O . LYS C 2 228 ? 124.772 -17.829 30.065 1.00 134.67 ? 211 LYS H O 1 ATOM 4943 C CB . LYS C 2 228 ? 123.865 -19.874 32.476 1.00 134.93 ? 211 LYS H CB 1 ATOM 4944 C CG . LYS C 2 228 ? 123.235 -20.212 33.823 1.00 134.51 ? 211 LYS H CG 1 ATOM 4945 C CD . LYS C 2 228 ? 124.219 -20.024 34.969 1.00 133.83 ? 211 LYS H CD 1 ATOM 4946 C CE . LYS C 2 228 ? 123.524 -20.124 36.317 1.00 132.97 ? 211 LYS H CE 1 ATOM 4947 N NZ . LYS C 2 228 ? 122.911 -21.459 36.530 1.00 132.62 ? 211 LYS H NZ 1 ATOM 4948 N N . ASN C 2 229 ? 126.501 -18.650 31.252 1.00 135.29 ? 212 ASN H N 1 ATOM 4949 C CA . ASN C 2 229 ? 127.450 -18.566 30.150 1.00 135.67 ? 212 ASN H CA 1 ATOM 4950 C C . ASN C 2 229 ? 127.655 -19.927 29.508 1.00 136.11 ? 212 ASN H C 1 ATOM 4951 O O . ASN C 2 229 ? 127.699 -20.949 30.194 1.00 135.88 ? 212 ASN H O 1 ATOM 4952 C CB . ASN C 2 229 ? 128.798 -18.036 30.639 1.00 135.76 ? 212 ASN H CB 1 ATOM 4953 C CG . ASN C 2 229 ? 128.721 -16.604 31.114 1.00 136.02 ? 212 ASN H CG 1 ATOM 4954 O OD1 . ASN C 2 229 ? 128.233 -15.729 30.400 1.00 136.23 ? 212 ASN H OD1 1 ATOM 4955 N ND2 . ASN C 2 229 ? 129.212 -16.353 32.323 1.00 136.11 ? 212 ASN H ND2 1 ATOM 4956 N N . VAL C 2 230 ? 127.786 -19.929 28.185 1.00 136.79 ? 213 VAL H N 1 ATOM 4957 C CA . VAL C 2 230 ? 127.986 -21.159 27.428 1.00 137.00 ? 213 VAL H CA 1 ATOM 4958 C C . VAL C 2 230 ? 129.401 -21.216 26.854 1.00 136.79 ? 213 VAL H C 1 ATOM 4959 O O . VAL C 2 230 ? 129.800 -20.352 26.071 1.00 136.54 ? 213 VAL H O 1 ATOM 4960 C CB . VAL C 2 230 ? 126.974 -21.268 26.261 1.00 137.27 ? 213 VAL H CB 1 ATOM 4961 C CG1 . VAL C 2 230 ? 127.115 -22.617 25.578 1.00 137.59 ? 213 VAL H CG1 1 ATOM 4962 C CG2 . VAL C 2 230 ? 125.553 -21.074 26.778 1.00 137.30 ? 213 VAL H CG2 1 ATOM 4963 N N . PRO C 2 231 ? 130.178 -22.242 27.240 1.00 136.81 ? 214 PRO H N 1 ATOM 4964 C CA . PRO C 2 231 ? 131.557 -22.430 26.774 1.00 136.74 ? 214 PRO H CA 1 ATOM 4965 C C . PRO C 2 231 ? 131.678 -22.681 25.269 1.00 136.36 ? 214 PRO H C 1 ATOM 4966 O O . PRO C 2 231 ? 132.174 -23.761 24.884 1.00 135.87 ? 214 PRO H O 1 ATOM 4967 C CB . PRO C 2 231 ? 132.041 -23.617 27.609 1.00 136.82 ? 214 PRO H CB 1 ATOM 4968 C CG . PRO C 2 231 ? 130.783 -24.400 27.836 1.00 136.73 ? 214 PRO H CG 1 ATOM 4969 C CD . PRO C 2 231 ? 129.792 -23.316 28.173 1.00 136.84 ? 214 PRO H CD 1 ATOM 4970 O OXT . PRO C 2 231 ? 131.282 -21.789 24.492 1.00 136.22 ? 214 PRO H OXT 1 ATOM 4971 N N . GLN D 2 12 ? 76.060 0.124 -9.663 1.00 64.61 ? 1 GLN I N 1 ATOM 4972 C CA . GLN D 2 12 ? 74.606 -0.146 -9.913 1.00 63.24 ? 1 GLN I CA 1 ATOM 4973 C C . GLN D 2 12 ? 73.857 1.171 -10.112 1.00 62.83 ? 1 GLN I C 1 ATOM 4974 O O . GLN D 2 12 ? 72.929 1.246 -10.918 1.00 62.21 ? 1 GLN I O 1 ATOM 4975 C CB . GLN D 2 12 ? 73.996 -0.917 -8.734 1.00 61.65 ? 1 GLN I CB 1 ATOM 4976 C CG . GLN D 2 12 ? 74.026 -0.149 -7.430 1.00 58.55 ? 1 GLN I CG 1 ATOM 4977 C CD . GLN D 2 12 ? 75.423 0.300 -7.069 1.00 58.12 ? 1 GLN I CD 1 ATOM 4978 O OE1 . GLN D 2 12 ? 76.188 -0.447 -6.465 1.00 57.10 ? 1 GLN I OE1 1 ATOM 4979 N NE2 . GLN D 2 12 ? 75.775 1.523 -7.464 1.00 58.06 ? 1 GLN I NE2 1 ATOM 4980 N N . LEU D 2 13 ? 74.275 2.202 -9.376 1.00 61.43 ? 2 LEU I N 1 ATOM 4981 C CA . LEU D 2 13 ? 73.659 3.520 -9.461 1.00 60.16 ? 2 LEU I CA 1 ATOM 4982 C C . LEU D 2 13 ? 74.262 4.336 -10.601 1.00 59.61 ? 2 LEU I C 1 ATOM 4983 O O . LEU D 2 13 ? 75.474 4.501 -10.684 1.00 60.93 ? 2 LEU I O 1 ATOM 4984 C CB . LEU D 2 13 ? 73.855 4.277 -8.154 1.00 59.69 ? 2 LEU I CB 1 ATOM 4985 C CG . LEU D 2 13 ? 73.137 5.626 -8.092 1.00 60.93 ? 2 LEU I CG 1 ATOM 4986 C CD1 . LEU D 2 13 ? 71.631 5.388 -8.057 1.00 60.95 ? 2 LEU I CD1 1 ATOM 4987 C CD2 . LEU D 2 13 ? 73.582 6.403 -6.860 1.00 60.14 ? 2 LEU I CD2 1 ATOM 4988 N N . GLN D 2 14 ? 73.415 4.852 -11.479 1.00 57.91 ? 3 GLN I N 1 ATOM 4989 C CA . GLN D 2 14 ? 73.894 5.639 -12.594 1.00 55.76 ? 3 GLN I CA 1 ATOM 4990 C C . GLN D 2 14 ? 72.913 6.751 -12.887 1.00 54.78 ? 3 GLN I C 1 ATOM 4991 O O . GLN D 2 14 ? 71.707 6.602 -12.694 1.00 53.45 ? 3 GLN I O 1 ATOM 4992 C CB . GLN D 2 14 ? 74.057 4.763 -13.828 1.00 57.93 ? 3 GLN I CB 1 ATOM 4993 C CG . GLN D 2 14 ? 74.937 3.544 -13.621 1.00 59.97 ? 3 GLN I CG 1 ATOM 4994 C CD . GLN D 2 14 ? 75.048 2.682 -14.875 1.00 62.34 ? 3 GLN I CD 1 ATOM 4995 O OE1 . GLN D 2 14 ? 74.046 2.137 -15.367 1.00 63.07 ? 3 GLN I OE1 1 ATOM 4996 N NE2 . GLN D 2 14 ? 76.271 2.554 -15.400 1.00 62.09 ? 3 GLN I NE2 1 ATOM 4997 N N . LEU D 2 15 ? 73.451 7.869 -13.355 1.00 54.15 ? 4 LEU I N 1 ATOM 4998 C CA . LEU D 2 15 ? 72.655 9.045 -13.677 1.00 52.84 ? 4 LEU I CA 1 ATOM 4999 C C . LEU D 2 15 ? 72.830 9.450 -15.136 1.00 52.54 ? 4 LEU I C 1 ATOM 5000 O O . LEU D 2 15 ? 73.946 9.514 -15.654 1.00 52.18 ? 4 LEU I O 1 ATOM 5001 C CB . LEU D 2 15 ? 73.048 10.204 -12.760 1.00 51.09 ? 4 LEU I CB 1 ATOM 5002 C CG . LEU D 2 15 ? 72.727 10.013 -11.279 1.00 49.84 ? 4 LEU I CG 1 ATOM 5003 C CD1 . LEU D 2 15 ? 73.445 8.804 -10.733 1.00 50.21 ? 4 LEU I CD1 1 ATOM 5004 C CD2 . LEU D 2 15 ? 73.149 11.240 -10.522 1.00 50.81 ? 4 LEU I CD2 1 ATOM 5005 N N . GLN D 2 16 ? 71.713 9.735 -15.789 1.00 52.60 ? 5 GLN I N 1 ATOM 5006 C CA . GLN D 2 16 ? 71.724 10.113 -17.188 1.00 52.98 ? 5 GLN I CA 1 ATOM 5007 C C . GLN D 2 16 ? 71.132 11.507 -17.405 1.00 52.99 ? 5 GLN I C 1 ATOM 5008 O O . GLN D 2 16 ? 69.949 11.733 -17.141 1.00 53.51 ? 5 GLN I O 1 ATOM 5009 C CB . GLN D 2 16 ? 70.932 9.075 -17.974 1.00 54.75 ? 5 GLN I CB 1 ATOM 5010 C CG . GLN D 2 16 ? 71.114 9.128 -19.466 1.00 59.61 ? 5 GLN I CG 1 ATOM 5011 C CD . GLN D 2 16 ? 72.562 8.996 -19.861 1.00 63.16 ? 5 GLN I CD 1 ATOM 5012 O OE1 . GLN D 2 16 ? 73.277 9.998 -19.991 1.00 64.78 ? 5 GLN I OE1 1 ATOM 5013 N NE2 . GLN D 2 16 ? 73.020 7.751 -20.035 1.00 63.07 ? 5 GLN I NE2 1 ATOM 5014 N N . GLU D 2 17 ? 71.956 12.442 -17.872 1.00 52.45 ? 6 GLU I N 1 ATOM 5015 C CA . GLU D 2 17 ? 71.488 13.795 -18.144 1.00 52.09 ? 6 GLU I CA 1 ATOM 5016 C C . GLU D 2 17 ? 70.766 13.771 -19.471 1.00 52.66 ? 6 GLU I C 1 ATOM 5017 O O . GLU D 2 17 ? 71.106 12.986 -20.343 1.00 52.59 ? 6 GLU I O 1 ATOM 5018 C CB . GLU D 2 17 ? 72.642 14.781 -18.254 1.00 51.54 ? 6 GLU I CB 1 ATOM 5019 C CG . GLU D 2 17 ? 73.393 15.018 -16.971 1.00 53.26 ? 6 GLU I CG 1 ATOM 5020 C CD . GLU D 2 17 ? 74.467 13.992 -16.722 1.00 52.56 ? 6 GLU I CD 1 ATOM 5021 O OE1 . GLU D 2 17 ? 75.095 14.050 -15.646 1.00 53.80 ? 6 GLU I OE1 1 ATOM 5022 O OE2 . GLU D 2 17 ? 74.690 13.136 -17.601 1.00 52.58 ? 6 GLU I OE2 1 ATOM 5023 N N . SER D 2 18 ? 69.762 14.629 -19.610 1.00 54.44 ? 7 SER I N 1 ATOM 5024 C CA . SER D 2 18 ? 68.978 14.733 -20.836 1.00 54.55 ? 7 SER I CA 1 ATOM 5025 C C . SER D 2 18 ? 68.602 16.182 -21.023 1.00 55.44 ? 7 SER I C 1 ATOM 5026 O O . SER D 2 18 ? 68.131 16.845 -20.093 1.00 53.99 ? 7 SER I O 1 ATOM 5027 C CB . SER D 2 18 ? 67.696 13.908 -20.760 1.00 52.14 ? 7 SER I CB 1 ATOM 5028 O OG . SER D 2 18 ? 67.996 12.562 -20.471 1.00 56.88 ? 7 SER I OG 1 ATOM 5029 N N . GLY D 2 19 ? 68.821 16.666 -22.236 1.00 56.50 ? 8 GLY I N 1 ATOM 5030 C CA . GLY D 2 19 ? 68.480 18.030 -22.550 1.00 58.18 ? 8 GLY I CA 1 ATOM 5031 C C . GLY D 2 19 ? 68.942 18.363 -23.942 1.00 58.47 ? 8 GLY I C 1 ATOM 5032 O O . GLY D 2 19 ? 69.887 17.754 -24.439 1.00 60.28 ? 8 GLY I O 1 ATOM 5033 N N . PRO D 2 20 ? 68.283 19.316 -24.606 1.00 57.74 ? 9 PRO I N 1 ATOM 5034 C CA . PRO D 2 20 ? 68.658 19.717 -25.961 1.00 57.24 ? 9 PRO I CA 1 ATOM 5035 C C . PRO D 2 20 ? 69.997 20.418 -25.827 1.00 55.79 ? 9 PRO I C 1 ATOM 5036 O O . PRO D 2 20 ? 70.159 21.261 -24.955 1.00 56.90 ? 9 PRO I O 1 ATOM 5037 C CB . PRO D 2 20 ? 67.543 20.667 -26.343 1.00 58.64 ? 9 PRO I CB 1 ATOM 5038 C CG . PRO D 2 20 ? 67.248 21.333 -25.031 1.00 58.49 ? 9 PRO I CG 1 ATOM 5039 C CD . PRO D 2 20 ? 67.210 20.174 -24.084 1.00 57.77 ? 9 PRO I CD 1 ATOM 5040 N N . GLY D 2 21 ? 70.952 20.061 -26.676 1.00 53.48 ? 10 GLY I N 1 ATOM 5041 C CA . GLY D 2 21 ? 72.274 20.652 -26.592 1.00 50.21 ? 10 GLY I CA 1 ATOM 5042 C C . GLY D 2 21 ? 72.353 22.079 -27.068 1.00 48.92 ? 10 GLY I C 1 ATOM 5043 O O . GLY D 2 21 ? 73.379 22.739 -26.899 1.00 49.98 ? 10 GLY I O 1 ATOM 5044 N N . LEU D 2 22 ? 71.273 22.560 -27.674 1.00 47.15 ? 11 LEU I N 1 ATOM 5045 C CA . LEU D 2 22 ? 71.234 23.926 -28.169 1.00 43.75 ? 11 LEU I CA 1 ATOM 5046 C C . LEU D 2 22 ? 70.094 24.713 -27.575 1.00 44.34 ? 11 LEU I C 1 ATOM 5047 O O . LEU D 2 22 ? 68.962 24.222 -27.486 1.00 45.44 ? 11 LEU I O 1 ATOM 5048 C CB . LEU D 2 22 ? 71.128 23.946 -29.691 1.00 41.29 ? 11 LEU I CB 1 ATOM 5049 C CG . LEU D 2 22 ? 72.513 23.948 -30.334 1.00 41.62 ? 11 LEU I CG 1 ATOM 5050 C CD1 . LEU D 2 22 ? 72.449 24.109 -31.842 1.00 39.97 ? 11 LEU I CD1 1 ATOM 5051 C CD2 . LEU D 2 22 ? 73.290 25.093 -29.719 1.00 43.22 ? 11 LEU I CD2 1 ATOM 5052 N N . VAL D 2 23 ? 70.403 25.939 -27.161 1.00 42.72 ? 12 VAL I N 1 ATOM 5053 C CA . VAL D 2 23 ? 69.414 26.830 -26.583 1.00 41.21 ? 12 VAL I CA 1 ATOM 5054 C C . VAL D 2 23 ? 69.767 28.267 -26.916 1.00 41.70 ? 12 VAL I C 1 ATOM 5055 O O . VAL D 2 23 ? 70.924 28.677 -26.799 1.00 43.08 ? 12 VAL I O 1 ATOM 5056 C CB . VAL D 2 23 ? 69.340 26.630 -25.075 1.00 40.65 ? 12 VAL I CB 1 ATOM 5057 C CG1 . VAL D 2 23 ? 68.772 27.845 -24.403 1.00 41.20 ? 12 VAL I CG1 1 ATOM 5058 C CG2 . VAL D 2 23 ? 68.459 25.437 -24.780 1.00 43.04 ? 12 VAL I CG2 1 ATOM 5059 N N . LYS D 2 24 ? 68.760 29.027 -27.334 1.00 40.10 ? 13 LYS I N 1 ATOM 5060 C CA . LYS D 2 24 ? 68.949 30.426 -27.716 1.00 38.72 ? 13 LYS I CA 1 ATOM 5061 C C . LYS D 2 24 ? 69.034 31.361 -26.536 1.00 38.62 ? 13 LYS I C 1 ATOM 5062 O O . LYS D 2 24 ? 68.508 31.071 -25.481 1.00 38.62 ? 13 LYS I O 1 ATOM 5063 C CB . LYS D 2 24 ? 67.809 30.873 -28.635 1.00 37.49 ? 13 LYS I CB 1 ATOM 5064 C CG . LYS D 2 24 ? 67.913 30.309 -30.037 1.00 36.50 ? 13 LYS I CG 1 ATOM 5065 C CD . LYS D 2 24 ? 66.630 30.441 -30.804 1.00 35.48 ? 13 LYS I CD 1 ATOM 5066 C CE . LYS D 2 24 ? 66.833 29.999 -32.255 1.00 38.58 ? 13 LYS I CE 1 ATOM 5067 N NZ . LYS D 2 24 ? 67.036 28.518 -32.418 1.00 40.18 ? 13 LYS I NZ 1 ATOM 5068 N N . PRO D 2 25 ? 69.697 32.514 -26.703 1.00 40.38 ? 14 PRO I N 1 ATOM 5069 C CA . PRO D 2 25 ? 69.806 33.456 -25.588 1.00 40.38 ? 14 PRO I CA 1 ATOM 5070 C C . PRO D 2 25 ? 68.429 33.884 -25.109 1.00 42.39 ? 14 PRO I C 1 ATOM 5071 O O . PRO D 2 25 ? 67.484 33.920 -25.892 1.00 42.61 ? 14 PRO I O 1 ATOM 5072 C CB . PRO D 2 25 ? 70.593 34.603 -26.193 1.00 37.95 ? 14 PRO I CB 1 ATOM 5073 C CG . PRO D 2 25 ? 71.466 33.903 -27.194 1.00 38.89 ? 14 PRO I CG 1 ATOM 5074 C CD . PRO D 2 25 ? 70.492 32.979 -27.852 1.00 39.88 ? 14 PRO I CD 1 ATOM 5075 N N . SER D 2 26 ? 68.321 34.185 -23.819 1.00 44.21 ? 15 SER I N 1 ATOM 5076 C CA . SER D 2 26 ? 67.066 34.608 -23.228 1.00 45.13 ? 15 SER I CA 1 ATOM 5077 C C . SER D 2 26 ? 66.058 33.471 -23.098 1.00 46.21 ? 15 SER I C 1 ATOM 5078 O O . SER D 2 26 ? 65.147 33.545 -22.284 1.00 49.94 ? 15 SER I O 1 ATOM 5079 C CB . SER D 2 26 ? 66.463 35.740 -24.039 1.00 46.95 ? 15 SER I CB 1 ATOM 5080 O OG . SER D 2 26 ? 65.348 36.284 -23.364 1.00 52.79 ? 15 SER I OG 1 ATOM 5081 N N . GLU D 2 27 ? 66.190 32.423 -23.899 1.00 45.74 ? 16 GLU I N 1 ATOM 5082 C CA . GLU D 2 27 ? 65.281 31.289 -23.763 1.00 46.46 ? 16 GLU I CA 1 ATOM 5083 C C . GLU D 2 27 ? 65.639 30.597 -22.456 1.00 45.51 ? 16 GLU I C 1 ATOM 5084 O O . GLU D 2 27 ? 66.558 31.033 -21.772 1.00 47.87 ? 16 GLU I O 1 ATOM 5085 C CB . GLU D 2 27 ? 65.469 30.322 -24.916 1.00 49.16 ? 16 GLU I CB 1 ATOM 5086 C CG . GLU D 2 27 ? 64.817 30.778 -26.187 1.00 54.79 ? 16 GLU I CG 1 ATOM 5087 C CD . GLU D 2 27 ? 65.048 29.813 -27.314 1.00 59.97 ? 16 GLU I CD 1 ATOM 5088 O OE1 . GLU D 2 27 ? 64.381 29.972 -28.365 1.00 64.12 ? 16 GLU I OE1 1 ATOM 5089 O OE2 . GLU D 2 27 ? 65.902 28.904 -27.147 1.00 60.87 ? 16 GLU I OE2 1 ATOM 5090 N N . THR D 2 28 ? 64.950 29.526 -22.084 1.00 43.92 ? 17 THR I N 1 ATOM 5091 C CA . THR D 2 28 ? 65.318 28.889 -20.821 1.00 43.76 ? 17 THR I CA 1 ATOM 5092 C C . THR D 2 28 ? 65.759 27.440 -20.969 1.00 41.93 ? 17 THR I C 1 ATOM 5093 O O . THR D 2 28 ? 65.128 26.665 -21.678 1.00 41.31 ? 17 THR I O 1 ATOM 5094 C CB . THR D 2 28 ? 64.179 28.984 -19.760 1.00 43.94 ? 17 THR I CB 1 ATOM 5095 O OG1 . THR D 2 28 ? 63.189 27.983 -20.010 1.00 44.28 ? 17 THR I OG1 1 ATOM 5096 C CG2 . THR D 2 28 ? 63.524 30.361 -19.810 1.00 45.01 ? 17 THR I CG2 1 ATOM 5097 N N . LEU D 2 29 ? 66.861 27.112 -20.288 1.00 40.21 ? 18 LEU I N 1 ATOM 5098 C CA . LEU D 2 29 ? 67.485 25.789 -20.280 1.00 37.29 ? 18 LEU I CA 1 ATOM 5099 C C . LEU D 2 29 ? 66.713 24.798 -19.429 1.00 36.11 ? 18 LEU I C 1 ATOM 5100 O O . LEU D 2 29 ? 66.437 25.056 -18.265 1.00 36.38 ? 18 LEU I O 1 ATOM 5101 C CB . LEU D 2 29 ? 68.910 25.905 -19.732 1.00 38.08 ? 18 LEU I CB 1 ATOM 5102 C CG . LEU D 2 29 ? 69.749 24.636 -19.554 1.00 36.75 ? 18 LEU I CG 1 ATOM 5103 C CD1 . LEU D 2 29 ? 69.870 23.939 -20.888 1.00 38.07 ? 18 LEU I CD1 1 ATOM 5104 C CD2 . LEU D 2 29 ? 71.126 24.984 -19.012 1.00 34.67 ? 18 LEU I CD2 1 ATOM 5105 N N . SER D 2 30 ? 66.386 23.652 -20.005 1.00 35.49 ? 19 SER I N 1 ATOM 5106 C CA . SER D 2 30 ? 65.646 22.635 -19.280 1.00 34.28 ? 19 SER I CA 1 ATOM 5107 C C . SER D 2 30 ? 66.259 21.236 -19.423 1.00 33.11 ? 19 SER I C 1 ATOM 5108 O O . SER D 2 30 ? 66.244 20.630 -20.497 1.00 30.72 ? 19 SER I O 1 ATOM 5109 C CB . SER D 2 30 ? 64.195 22.631 -19.755 1.00 35.68 ? 19 SER I CB 1 ATOM 5110 O OG . SER D 2 30 ? 63.513 21.494 -19.257 1.00 40.89 ? 19 SER I OG 1 ATOM 5111 N N . LEU D 2 31 ? 66.781 20.726 -18.315 1.00 32.68 ? 20 LEU I N 1 ATOM 5112 C CA . LEU D 2 31 ? 67.415 19.414 -18.283 1.00 31.98 ? 20 LEU I CA 1 ATOM 5113 C C . LEU D 2 31 ? 66.708 18.448 -17.346 1.00 31.68 ? 20 LEU I C 1 ATOM 5114 O O . LEU D 2 31 ? 66.131 18.854 -16.351 1.00 32.51 ? 20 LEU I O 1 ATOM 5115 C CB . LEU D 2 31 ? 68.870 19.556 -17.817 1.00 29.26 ? 20 LEU I CB 1 ATOM 5116 C CG . LEU D 2 31 ? 69.809 20.431 -18.637 1.00 26.66 ? 20 LEU I CG 1 ATOM 5117 C CD1 . LEU D 2 31 ? 71.111 20.552 -17.921 1.00 28.08 ? 20 LEU I CD1 1 ATOM 5118 C CD2 . LEU D 2 31 ? 70.038 19.828 -19.989 1.00 26.24 ? 20 LEU I CD2 1 ATOM 5119 N N . THR D 2 32 ? 66.770 17.163 -17.657 1.00 32.62 ? 21 THR I N 1 ATOM 5120 C CA . THR D 2 32 ? 66.170 16.152 -16.791 1.00 33.72 ? 21 THR I CA 1 ATOM 5121 C C . THR D 2 32 ? 67.204 15.071 -16.522 1.00 35.64 ? 21 THR I C 1 ATOM 5122 O O . THR D 2 32 ? 67.909 14.653 -17.425 1.00 36.24 ? 21 THR I O 1 ATOM 5123 C CB . THR D 2 32 ? 64.916 15.516 -17.440 1.00 32.37 ? 21 THR I CB 1 ATOM 5124 O OG1 . THR D 2 32 ? 63.779 16.349 -17.187 1.00 32.83 ? 21 THR I OG1 1 ATOM 5125 C CG2 . THR D 2 32 ? 64.646 14.137 -16.881 1.00 29.41 ? 21 THR I CG2 1 ATOM 5126 N N . CYS D 2 33 ? 67.309 14.631 -15.275 1.00 38.23 ? 22 CYS I N 1 ATOM 5127 C CA . CYS D 2 33 ? 68.255 13.574 -14.934 1.00 41.71 ? 22 CYS I CA 1 ATOM 5128 C C . CYS D 2 33 ? 67.445 12.314 -14.656 1.00 43.34 ? 22 CYS I C 1 ATOM 5129 O O . CYS D 2 33 ? 66.443 12.361 -13.942 1.00 42.69 ? 22 CYS I O 1 ATOM 5130 C CB . CYS D 2 33 ? 69.059 13.970 -13.697 1.00 42.24 ? 22 CYS I CB 1 ATOM 5131 S SG . CYS D 2 33 ? 70.417 12.887 -13.101 1.00 43.46 ? 22 CYS I SG 1 ATOM 5132 N N . THR D 2 34 ? 67.869 11.203 -15.250 1.00 45.28 ? 23 THR I N 1 ATOM 5133 C CA . THR D 2 34 ? 67.199 9.927 -15.059 1.00 47.86 ? 23 THR I CA 1 ATOM 5134 C C . THR D 2 34 ? 68.091 9.002 -14.245 1.00 49.60 ? 23 THR I C 1 ATOM 5135 O O . THR D 2 34 ? 69.169 8.606 -14.688 1.00 51.60 ? 23 THR I O 1 ATOM 5136 C CB . THR D 2 34 ? 66.887 9.263 -16.387 1.00 48.91 ? 23 THR I CB 1 ATOM 5137 O OG1 . THR D 2 34 ? 65.926 10.052 -17.096 1.00 52.80 ? 23 THR I OG1 1 ATOM 5138 C CG2 . THR D 2 34 ? 66.326 7.882 -16.163 1.00 50.60 ? 23 THR I CG2 1 ATOM 5139 N N . VAL D 2 35 ? 67.613 8.659 -13.055 1.00 49.88 ? 24 VAL I N 1 ATOM 5140 C CA . VAL D 2 35 ? 68.324 7.819 -12.109 1.00 48.94 ? 24 VAL I CA 1 ATOM 5141 C C . VAL D 2 35 ? 67.940 6.348 -12.194 1.00 48.70 ? 24 VAL I C 1 ATOM 5142 O O . VAL D 2 35 ? 66.764 6.004 -12.202 1.00 48.65 ? 24 VAL I O 1 ATOM 5143 C CB . VAL D 2 35 ? 68.047 8.337 -10.687 1.00 50.64 ? 24 VAL I CB 1 ATOM 5144 C CG1 . VAL D 2 35 ? 68.700 7.442 -9.652 1.00 51.39 ? 24 VAL I CG1 1 ATOM 5145 C CG2 . VAL D 2 35 ? 68.549 9.765 -10.565 1.00 50.68 ? 24 VAL I CG2 1 ATOM 5146 N N . SER D 2 36 ? 68.945 5.479 -12.246 1.00 49.70 ? 25 SER I N 1 ATOM 5147 C CA . SER D 2 36 ? 68.715 4.030 -12.315 1.00 48.98 ? 25 SER I CA 1 ATOM 5148 C C . SER D 2 36 ? 69.571 3.310 -11.277 1.00 48.56 ? 25 SER I C 1 ATOM 5149 O O . SER D 2 36 ? 70.697 3.725 -11.002 1.00 47.62 ? 25 SER I O 1 ATOM 5150 C CB . SER D 2 36 ? 69.040 3.499 -13.718 1.00 48.09 ? 25 SER I CB 1 ATOM 5151 O OG . SER D 2 36 ? 70.386 3.764 -14.072 1.00 45.41 ? 25 SER I OG 1 ATOM 5152 N N . GLY D 2 37 ? 69.030 2.239 -10.697 1.00 48.95 ? 26 GLY I N 1 ATOM 5153 C CA . GLY D 2 37 ? 69.757 1.487 -9.680 1.00 48.44 ? 26 GLY I CA 1 ATOM 5154 C C . GLY D 2 37 ? 69.870 2.262 -8.378 1.00 47.62 ? 26 GLY I C 1 ATOM 5155 O O . GLY D 2 37 ? 70.951 2.403 -7.812 1.00 48.23 ? 26 GLY I O 1 ATOM 5156 N N . GLY D 2 38 ? 68.738 2.761 -7.902 1.00 46.00 ? 27 GLY I N 1 ATOM 5157 C CA . GLY D 2 38 ? 68.712 3.545 -6.685 1.00 45.15 ? 27 GLY I CA 1 ATOM 5158 C C . GLY D 2 38 ? 67.499 4.445 -6.782 1.00 45.60 ? 27 GLY I C 1 ATOM 5159 O O . GLY D 2 38 ? 67.279 5.076 -7.811 1.00 47.15 ? 27 GLY I O 1 ATOM 5160 N N . SER D 2 39 ? 66.696 4.510 -5.732 1.00 45.02 ? 28 SER I N 1 ATOM 5161 C CA . SER D 2 39 ? 65.508 5.338 -5.789 1.00 45.31 ? 28 SER I CA 1 ATOM 5162 C C . SER D 2 39 ? 65.635 6.620 -5.019 1.00 44.74 ? 28 SER I C 1 ATOM 5163 O O . SER D 2 39 ? 65.873 6.603 -3.817 1.00 45.35 ? 28 SER I O 1 ATOM 5164 C CB . SER D 2 39 ? 64.288 4.586 -5.267 1.00 46.61 ? 28 SER I CB 1 ATOM 5165 O OG . SER D 2 39 ? 63.222 5.503 -5.055 1.00 48.81 ? 28 SER I OG 1 ATOM 5166 N N . ILE D 2 40 ? 65.444 7.727 -5.727 1.00 43.43 ? 29 ILE I N 1 ATOM 5167 C CA . ILE D 2 40 ? 65.513 9.065 -5.156 1.00 39.99 ? 29 ILE I CA 1 ATOM 5168 C C . ILE D 2 40 ? 64.543 9.195 -3.990 1.00 40.41 ? 29 ILE I C 1 ATOM 5169 O O . ILE D 2 40 ? 64.777 9.978 -3.072 1.00 38.86 ? 29 ILE I O 1 ATOM 5170 C CB . ILE D 2 40 ? 65.161 10.111 -6.234 1.00 38.23 ? 29 ILE I CB 1 ATOM 5171 C CG1 . ILE D 2 40 ? 66.283 10.160 -7.259 1.00 36.87 ? 29 ILE I CG1 1 ATOM 5172 C CG2 . ILE D 2 40 ? 64.888 11.465 -5.617 1.00 33.47 ? 29 ILE I CG2 1 ATOM 5173 C CD1 . ILE D 2 40 ? 66.010 11.086 -8.376 1.00 39.76 ? 29 ILE I CD1 1 ATOM 5174 N N . SER D 2 41 ? 63.459 8.420 -4.024 1.00 40.54 ? 30 SER I N 1 ATOM 5175 C CA . SER D 2 41 ? 62.469 8.491 -2.961 1.00 41.51 ? 30 SER I CA 1 ATOM 5176 C C . SER D 2 41 ? 62.960 7.824 -1.669 1.00 40.49 ? 30 SER I C 1 ATOM 5177 O O . SER D 2 41 ? 62.319 7.947 -0.624 1.00 40.31 ? 30 SER I O 1 ATOM 5178 C CB . SER D 2 41 ? 61.143 7.874 -3.416 1.00 42.37 ? 30 SER I CB 1 ATOM 5179 O OG . SER D 2 41 ? 61.185 6.455 -3.377 1.00 47.53 ? 30 SER I OG 1 ATOM 5180 N N . ARG D 2 42 ? 64.094 7.125 -1.737 1.00 39.06 ? 31 ARG I N 1 ATOM 5181 C CA . ARG D 2 42 ? 64.661 6.484 -0.549 1.00 37.48 ? 31 ARG I CA 1 ATOM 5182 C C . ARG D 2 42 ? 64.939 7.572 0.482 1.00 37.75 ? 31 ARG I C 1 ATOM 5183 O O . ARG D 2 42 ? 65.102 7.309 1.664 1.00 40.19 ? 31 ARG I O 1 ATOM 5184 C CB . ARG D 2 42 ? 65.953 5.742 -0.901 1.00 36.41 ? 31 ARG I CB 1 ATOM 5185 C CG . ARG D 2 42 ? 66.816 5.355 0.304 1.00 37.64 ? 31 ARG I CG 1 ATOM 5186 C CD . ARG D 2 42 ? 67.782 4.202 0.007 1.00 35.90 ? 31 ARG I CD 1 ATOM 5187 N NE . ARG D 2 42 ? 67.085 2.920 0.033 1.00 36.22 ? 31 ARG I NE 1 ATOM 5188 C CZ . ARG D 2 42 ? 66.889 2.194 1.130 1.00 39.23 ? 31 ARG I CZ 1 ATOM 5189 N NH1 . ARG D 2 42 ? 66.230 1.045 1.058 1.00 38.12 ? 31 ARG I NH1 1 ATOM 5190 N NH2 . ARG D 2 42 ? 67.379 2.598 2.299 1.00 43.01 ? 31 ARG I NH2 1 ATOM 5191 N N . GLY D 2 43 ? 65.000 8.805 0.013 1.00 37.01 ? 32 GLY I N 1 ATOM 5192 C CA . GLY D 2 43 ? 65.218 9.921 0.900 1.00 37.15 ? 32 GLY I CA 1 ATOM 5193 C C . GLY D 2 43 ? 66.474 9.864 1.717 1.00 37.88 ? 32 GLY I C 1 ATOM 5194 O O . GLY D 2 43 ? 66.565 10.569 2.727 1.00 39.86 ? 32 GLY I O 1 ATOM 5195 N N . SER D 2 44 ? 67.439 9.046 1.297 1.00 37.32 ? 33 SER I N 1 ATOM 5196 C CA . SER D 2 44 ? 68.707 8.929 2.025 1.00 35.97 ? 33 SER I CA 1 ATOM 5197 C C . SER D 2 44 ? 69.651 10.062 1.684 1.00 32.97 ? 33 SER I C 1 ATOM 5198 O O . SER D 2 44 ? 70.313 10.575 2.562 1.00 32.10 ? 33 SER I O 1 ATOM 5199 C CB . SER D 2 44 ? 69.388 7.586 1.748 1.00 39.27 ? 33 SER I CB 1 ATOM 5200 O OG . SER D 2 44 ? 69.504 7.333 0.352 1.00 48.20 ? 33 SER I OG 1 ATOM 5201 N N . HIS D 2 45 ? 69.707 10.467 0.420 1.00 32.48 ? 34 HIS I N 1 ATOM 5202 C CA . HIS D 2 45 ? 70.579 11.579 0.037 1.00 35.24 ? 34 HIS I CA 1 ATOM 5203 C C . HIS D 2 45 ? 69.909 12.696 -0.792 1.00 34.65 ? 34 HIS I C 1 ATOM 5204 O O . HIS D 2 45 ? 68.770 12.559 -1.258 1.00 35.26 ? 34 HIS I O 1 ATOM 5205 C CB . HIS D 2 45 ? 71.751 11.079 -0.788 1.00 39.34 ? 34 HIS I CB 1 ATOM 5206 C CG . HIS D 2 45 ? 72.273 9.753 -0.368 1.00 44.36 ? 34 HIS I CG 1 ATOM 5207 N ND1 . HIS D 2 45 ? 72.951 9.561 0.815 1.00 48.68 ? 34 HIS I ND1 1 ATOM 5208 C CD2 . HIS D 2 45 ? 72.278 8.560 -1.005 1.00 46.75 ? 34 HIS I CD2 1 ATOM 5209 C CE1 . HIS D 2 45 ? 73.360 8.307 0.886 1.00 50.84 ? 34 HIS I CE1 1 ATOM 5210 N NE2 . HIS D 2 45 ? 72.965 7.679 -0.208 1.00 51.31 ? 34 HIS I NE2 1 ATOM 5211 N N . TYR D 2 46 ? 70.653 13.788 -0.984 1.00 31.11 ? 35 TYR I N 1 ATOM 5212 C CA . TYR D 2 46 ? 70.218 14.910 -1.807 1.00 30.20 ? 35 TYR I CA 1 ATOM 5213 C C . TYR D 2 46 ? 70.743 14.670 -3.240 1.00 30.10 ? 35 TYR I C 1 ATOM 5214 O O . TYR D 2 46 ? 71.512 13.754 -3.468 1.00 29.88 ? 35 TYR I O 1 ATOM 5215 C CB . TYR D 2 46 ? 70.784 16.216 -1.258 1.00 29.61 ? 35 TYR I CB 1 ATOM 5216 C CG . TYR D 2 46 ? 70.059 16.753 -0.051 1.00 27.26 ? 35 TYR I CG 1 ATOM 5217 C CD1 . TYR D 2 46 ? 68.996 17.639 -0.199 1.00 25.55 ? 35 TYR I CD1 1 ATOM 5218 C CD2 . TYR D 2 46 ? 70.419 16.354 1.240 1.00 25.26 ? 35 TYR I CD2 1 ATOM 5219 C CE1 . TYR D 2 46 ? 68.307 18.113 0.910 1.00 24.94 ? 35 TYR I CE1 1 ATOM 5220 C CE2 . TYR D 2 46 ? 69.738 16.818 2.352 1.00 22.49 ? 35 TYR I CE2 1 ATOM 5221 C CZ . TYR D 2 46 ? 68.681 17.696 2.181 1.00 24.09 ? 35 TYR I CZ 1 ATOM 5222 O OH . TYR D 2 46 ? 67.978 18.150 3.273 1.00 26.07 ? 35 TYR I OH 1 ATOM 5223 N N . TRP D 2 47 A 70.315 15.480 -4.205 1.00 30.72 ? 35 TRP I N 1 ATOM 5224 C CA . TRP D 2 47 A 70.740 15.323 -5.606 1.00 29.30 ? 35 TRP I CA 1 ATOM 5225 C C . TRP D 2 47 A 70.942 16.711 -6.221 1.00 30.22 ? 35 TRP I C 1 ATOM 5226 O O . TRP D 2 47 A 70.236 17.657 -5.877 1.00 32.66 ? 35 TRP I O 1 ATOM 5227 C CB . TRP D 2 47 A 69.682 14.540 -6.378 1.00 26.75 ? 35 TRP I CB 1 ATOM 5228 C CG . TRP D 2 47 A 69.265 13.288 -5.658 1.00 24.53 ? 35 TRP I CG 1 ATOM 5229 C CD1 . TRP D 2 47 A 68.522 13.208 -4.514 1.00 23.92 ? 35 TRP I CD1 1 ATOM 5230 C CD2 . TRP D 2 47 A 69.655 11.951 -5.973 1.00 23.10 ? 35 TRP I CD2 1 ATOM 5231 N NE1 . TRP D 2 47 A 68.435 11.906 -4.089 1.00 24.05 ? 35 TRP I NE1 1 ATOM 5232 C CE2 . TRP D 2 47 A 69.118 11.110 -4.969 1.00 24.30 ? 35 TRP I CE2 1 ATOM 5233 C CE3 . TRP D 2 47 A 70.413 11.379 -7.000 1.00 21.13 ? 35 TRP I CE3 1 ATOM 5234 C CZ2 . TRP D 2 47 A 69.312 9.722 -4.966 1.00 24.08 ? 35 TRP I CZ2 1 ATOM 5235 C CZ3 . TRP D 2 47 A 70.612 10.003 -6.993 1.00 23.98 ? 35 TRP I CZ3 1 ATOM 5236 C CH2 . TRP D 2 47 A 70.061 9.188 -5.980 1.00 22.39 ? 35 TRP I CH2 1 ATOM 5237 N N . GLY D 2 48 B 71.898 16.853 -7.126 1.00 28.03 ? 35 GLY I N 1 ATOM 5238 C CA . GLY D 2 48 B 72.131 18.178 -7.655 1.00 25.93 ? 35 GLY I CA 1 ATOM 5239 C C . GLY D 2 48 B 72.651 18.321 -9.060 1.00 25.33 ? 35 GLY I C 1 ATOM 5240 O O . GLY D 2 48 B 72.786 17.353 -9.798 1.00 25.38 ? 35 GLY I O 1 ATOM 5241 N N . TRP D 2 49 ? 72.931 19.567 -9.419 1.00 23.82 ? 36 TRP I N 1 ATOM 5242 C CA . TRP D 2 49 ? 73.432 19.899 -10.728 1.00 25.58 ? 36 TRP I CA 1 ATOM 5243 C C . TRP D 2 49 ? 74.709 20.693 -10.582 1.00 27.62 ? 36 TRP I C 1 ATOM 5244 O O . TRP D 2 49 ? 74.842 21.505 -9.670 1.00 28.31 ? 36 TRP I O 1 ATOM 5245 C CB . TRP D 2 49 ? 72.401 20.727 -11.504 1.00 26.15 ? 36 TRP I CB 1 ATOM 5246 C CG . TRP D 2 49 ? 71.113 19.999 -11.774 1.00 25.60 ? 36 TRP I CG 1 ATOM 5247 C CD1 . TRP D 2 49 ? 69.994 19.963 -10.976 1.00 25.36 ? 36 TRP I CD1 1 ATOM 5248 C CD2 . TRP D 2 49 ? 70.859 19.106 -12.856 1.00 22.45 ? 36 TRP I CD2 1 ATOM 5249 N NE1 . TRP D 2 49 ? 69.075 19.094 -11.496 1.00 22.91 ? 36 TRP I NE1 1 ATOM 5250 C CE2 . TRP D 2 49 ? 69.580 18.550 -12.647 1.00 22.13 ? 36 TRP I CE2 1 ATOM 5251 C CE3 . TRP D 2 49 ? 71.594 18.711 -13.976 1.00 21.87 ? 36 TRP I CE3 1 ATOM 5252 C CZ2 . TRP D 2 49 ? 69.023 17.625 -13.516 1.00 22.21 ? 36 TRP I CZ2 1 ATOM 5253 C CZ3 . TRP D 2 49 ? 71.042 17.792 -14.839 1.00 23.81 ? 36 TRP I CZ3 1 ATOM 5254 C CH2 . TRP D 2 49 ? 69.765 17.255 -14.605 1.00 23.66 ? 36 TRP I CH2 1 ATOM 5255 N N . ILE D 2 50 ? 75.653 20.436 -11.475 1.00 29.30 ? 37 ILE I N 1 ATOM 5256 C CA . ILE D 2 50 ? 76.927 21.136 -11.478 1.00 31.76 ? 37 ILE I CA 1 ATOM 5257 C C . ILE D 2 50 ? 77.288 21.331 -12.935 1.00 33.86 ? 37 ILE I C 1 ATOM 5258 O O . ILE D 2 50 ? 77.132 20.417 -13.745 1.00 36.62 ? 37 ILE I O 1 ATOM 5259 C CB . ILE D 2 50 ? 78.051 20.333 -10.783 1.00 30.58 ? 37 ILE I CB 1 ATOM 5260 C CG1 . ILE D 2 50 ? 77.722 20.119 -9.304 1.00 31.45 ? 37 ILE I CG1 1 ATOM 5261 C CG2 . ILE D 2 50 ? 79.344 21.105 -10.846 1.00 30.38 ? 37 ILE I CG2 1 ATOM 5262 C CD1 . ILE D 2 50 ? 76.981 18.847 -9.000 1.00 30.06 ? 37 ILE I CD1 1 ATOM 5263 N N . ARG D 2 51 ? 77.767 22.516 -13.279 1.00 33.88 ? 38 ARG I N 1 ATOM 5264 C CA . ARG D 2 51 ? 78.109 22.783 -14.662 1.00 34.37 ? 38 ARG I CA 1 ATOM 5265 C C . ARG D 2 51 ? 79.585 23.066 -14.790 1.00 35.44 ? 38 ARG I C 1 ATOM 5266 O O . ARG D 2 51 ? 80.266 23.331 -13.802 1.00 35.66 ? 38 ARG I O 1 ATOM 5267 C CB . ARG D 2 51 ? 77.332 23.988 -15.159 1.00 35.61 ? 38 ARG I CB 1 ATOM 5268 C CG . ARG D 2 51 ? 77.928 25.254 -14.644 1.00 35.41 ? 38 ARG I CG 1 ATOM 5269 C CD . ARG D 2 51 ? 76.894 26.245 -14.266 1.00 33.81 ? 38 ARG I CD 1 ATOM 5270 N NE . ARG D 2 51 ? 76.241 26.838 -15.415 1.00 31.21 ? 38 ARG I NE 1 ATOM 5271 C CZ . ARG D 2 51 ? 75.939 28.127 -15.483 1.00 31.11 ? 38 ARG I CZ 1 ATOM 5272 N NH1 . ARG D 2 51 ? 76.250 28.935 -14.479 1.00 25.45 ? 38 ARG I NH1 1 ATOM 5273 N NH2 . ARG D 2 51 ? 75.289 28.601 -16.534 1.00 35.63 ? 38 ARG I NH2 1 ATOM 5274 N N . GLN D 2 52 ? 80.063 23.050 -16.027 1.00 37.77 ? 39 GLN I N 1 ATOM 5275 C CA . GLN D 2 52 ? 81.469 23.272 -16.299 1.00 39.92 ? 39 GLN I CA 1 ATOM 5276 C C . GLN D 2 52 ? 81.746 23.926 -17.648 1.00 41.03 ? 39 GLN I C 1 ATOM 5277 O O . GLN D 2 52 ? 81.755 23.265 -18.689 1.00 41.41 ? 39 GLN I O 1 ATOM 5278 C CB . GLN D 2 52 ? 82.210 21.934 -16.210 1.00 38.70 ? 39 GLN I CB 1 ATOM 5279 C CG . GLN D 2 52 ? 83.668 22.032 -16.549 1.00 38.13 ? 39 GLN I CG 1 ATOM 5280 C CD . GLN D 2 52 ? 84.425 20.781 -16.220 1.00 39.68 ? 39 GLN I CD 1 ATOM 5281 O OE1 . GLN D 2 52 ? 84.020 19.669 -16.590 1.00 39.89 ? 39 GLN I OE1 1 ATOM 5282 N NE2 . GLN D 2 52 ? 85.541 20.945 -15.521 1.00 39.04 ? 39 GLN I NE2 1 ATOM 5283 N N . PRO D 2 53 ? 81.993 25.236 -17.643 1.00 41.94 ? 40 PRO I N 1 ATOM 5284 C CA . PRO D 2 53 ? 82.280 25.993 -18.862 1.00 45.39 ? 40 PRO I CA 1 ATOM 5285 C C . PRO D 2 53 ? 83.385 25.289 -19.658 1.00 50.74 ? 40 PRO I C 1 ATOM 5286 O O . PRO D 2 53 ? 84.349 24.792 -19.078 1.00 50.68 ? 40 PRO I O 1 ATOM 5287 C CB . PRO D 2 53 ? 82.721 27.337 -18.320 1.00 43.31 ? 40 PRO I CB 1 ATOM 5288 C CG . PRO D 2 53 ? 81.915 27.459 -17.080 1.00 42.88 ? 40 PRO I CG 1 ATOM 5289 C CD . PRO D 2 53 ? 82.031 26.104 -16.463 1.00 41.31 ? 40 PRO I CD 1 ATOM 5290 N N . PRO D 2 54 ? 83.278 25.276 -20.999 1.00 55.53 ? 41 PRO I N 1 ATOM 5291 C CA . PRO D 2 54 ? 84.252 24.628 -21.886 1.00 57.24 ? 41 PRO I CA 1 ATOM 5292 C C . PRO D 2 54 ? 85.674 24.430 -21.366 1.00 58.43 ? 41 PRO I C 1 ATOM 5293 O O . PRO D 2 54 ? 86.125 23.296 -21.198 1.00 61.04 ? 41 PRO I O 1 ATOM 5294 C CB . PRO D 2 54 ? 84.194 25.493 -23.138 1.00 56.66 ? 41 PRO I CB 1 ATOM 5295 C CG . PRO D 2 54 ? 82.746 25.797 -23.222 1.00 56.94 ? 41 PRO I CG 1 ATOM 5296 C CD . PRO D 2 54 ? 82.424 26.194 -21.778 1.00 57.11 ? 41 PRO I CD 1 ATOM 5297 N N . GLY D 2 55 ? 86.396 25.505 -21.110 1.00 58.37 ? 42 GLY I N 1 ATOM 5298 C CA . GLY D 2 55 ? 87.750 25.304 -20.638 1.00 60.21 ? 42 GLY I CA 1 ATOM 5299 C C . GLY D 2 55 ? 87.921 25.751 -19.210 1.00 61.63 ? 42 GLY I C 1 ATOM 5300 O O . GLY D 2 55 ? 89.021 26.119 -18.795 1.00 62.93 ? 42 GLY I O 1 ATOM 5301 N N . LYS D 2 56 ? 86.837 25.710 -18.444 1.00 61.56 ? 43 LYS I N 1 ATOM 5302 C CA . LYS D 2 56 ? 86.907 26.161 -17.069 1.00 60.10 ? 43 LYS I CA 1 ATOM 5303 C C . LYS D 2 56 ? 86.603 25.108 -16.016 1.00 57.90 ? 43 LYS I C 1 ATOM 5304 O O . LYS D 2 56 ? 86.455 23.926 -16.326 1.00 55.78 ? 43 LYS I O 1 ATOM 5305 C CB . LYS D 2 56 ? 86.007 27.391 -16.897 1.00 62.28 ? 43 LYS I CB 1 ATOM 5306 C CG . LYS D 2 56 ? 86.344 28.503 -17.888 1.00 64.21 ? 43 LYS I CG 1 ATOM 5307 C CD . LYS D 2 56 ? 87.865 28.729 -17.959 1.00 66.83 ? 43 LYS I CD 1 ATOM 5308 C CE . LYS D 2 56 ? 88.265 29.621 -19.143 1.00 69.24 ? 43 LYS I CE 1 ATOM 5309 N NZ . LYS D 2 56 ? 89.744 29.798 -19.276 1.00 67.92 ? 43 LYS I NZ 1 ATOM 5310 N N . GLY D 2 57 ? 86.534 25.563 -14.766 1.00 56.63 ? 44 GLY I N 1 ATOM 5311 C CA . GLY D 2 57 ? 86.282 24.679 -13.639 1.00 55.11 ? 44 GLY I CA 1 ATOM 5312 C C . GLY D 2 57 ? 84.863 24.204 -13.372 1.00 52.55 ? 44 GLY I C 1 ATOM 5313 O O . GLY D 2 57 ? 84.120 23.867 -14.297 1.00 52.46 ? 44 GLY I O 1 ATOM 5314 N N . LEU D 2 58 ? 84.494 24.177 -12.094 1.00 48.98 ? 45 LEU I N 1 ATOM 5315 C CA . LEU D 2 58 ? 83.179 23.708 -11.684 1.00 46.63 ? 45 LEU I CA 1 ATOM 5316 C C . LEU D 2 58 ? 82.341 24.725 -10.907 1.00 45.02 ? 45 LEU I C 1 ATOM 5317 O O . LEU D 2 58 ? 82.869 25.598 -10.225 1.00 46.30 ? 45 LEU I O 1 ATOM 5318 C CB . LEU D 2 58 ? 83.348 22.429 -10.861 1.00 45.26 ? 45 LEU I CB 1 ATOM 5319 C CG . LEU D 2 58 ? 83.910 21.225 -11.631 1.00 44.77 ? 45 LEU I CG 1 ATOM 5320 C CD1 . LEU D 2 58 ? 84.177 20.094 -10.675 1.00 45.14 ? 45 LEU I CD1 1 ATOM 5321 C CD2 . LEU D 2 58 ? 82.931 20.771 -12.698 1.00 42.83 ? 45 LEU I CD2 1 ATOM 5322 N N . GLU D 2 59 ? 81.024 24.614 -11.016 1.00 42.27 ? 46 GLU I N 1 ATOM 5323 C CA . GLU D 2 59 ? 80.134 25.523 -10.308 1.00 40.48 ? 46 GLU I CA 1 ATOM 5324 C C . GLU D 2 59 ? 78.900 24.757 -9.877 1.00 39.83 ? 46 GLU I C 1 ATOM 5325 O O . GLU D 2 59 ? 78.176 24.218 -10.711 1.00 40.38 ? 46 GLU I O 1 ATOM 5326 C CB . GLU D 2 59 ? 79.738 26.683 -11.215 1.00 40.72 ? 46 GLU I CB 1 ATOM 5327 C CG . GLU D 2 59 ? 78.680 27.597 -10.632 1.00 43.49 ? 46 GLU I CG 1 ATOM 5328 C CD . GLU D 2 59 ? 78.273 28.702 -11.591 1.00 44.59 ? 46 GLU I CD 1 ATOM 5329 O OE1 . GLU D 2 59 ? 78.186 28.414 -12.804 1.00 45.37 ? 46 GLU I OE1 1 ATOM 5330 O OE2 . GLU D 2 59 ? 78.029 29.846 -11.138 1.00 43.98 ? 46 GLU I OE2 1 ATOM 5331 N N . TRP D 2 60 ? 78.676 24.686 -8.570 1.00 38.76 ? 47 TRP I N 1 ATOM 5332 C CA . TRP D 2 60 ? 77.519 23.973 -8.030 1.00 36.44 ? 47 TRP I CA 1 ATOM 5333 C C . TRP D 2 60 ? 76.294 24.801 -8.371 1.00 33.40 ? 47 TRP I C 1 ATOM 5334 O O . TRP D 2 60 ? 76.297 26.004 -8.141 1.00 31.76 ? 47 TRP I O 1 ATOM 5335 C CB . TRP D 2 60 ? 77.651 23.825 -6.503 1.00 37.84 ? 47 TRP I CB 1 ATOM 5336 C CG . TRP D 2 60 ? 76.430 23.240 -5.815 1.00 38.97 ? 47 TRP I CG 1 ATOM 5337 C CD1 . TRP D 2 60 ? 75.891 22.003 -6.016 1.00 38.57 ? 47 TRP I CD1 1 ATOM 5338 C CD2 . TRP D 2 60 ? 75.620 23.868 -4.804 1.00 38.02 ? 47 TRP I CD2 1 ATOM 5339 N NE1 . TRP D 2 60 ? 74.802 21.821 -5.197 1.00 37.57 ? 47 TRP I NE1 1 ATOM 5340 C CE2 . TRP D 2 60 ? 74.615 22.947 -4.443 1.00 37.03 ? 47 TRP I CE2 1 ATOM 5341 C CE3 . TRP D 2 60 ? 75.648 25.120 -4.170 1.00 35.76 ? 47 TRP I CE3 1 ATOM 5342 C CZ2 . TRP D 2 60 ? 73.652 23.232 -3.478 1.00 37.43 ? 47 TRP I CZ2 1 ATOM 5343 C CZ3 . TRP D 2 60 ? 74.690 25.405 -3.211 1.00 34.44 ? 47 TRP I CZ3 1 ATOM 5344 C CH2 . TRP D 2 60 ? 73.706 24.467 -2.873 1.00 36.51 ? 47 TRP I CH2 1 ATOM 5345 N N . ILE D 2 61 ? 75.260 24.172 -8.923 1.00 31.57 ? 48 ILE I N 1 ATOM 5346 C CA . ILE D 2 61 ? 74.054 24.914 -9.272 1.00 31.60 ? 48 ILE I CA 1 ATOM 5347 C C . ILE D 2 61 ? 73.018 24.817 -8.164 1.00 32.29 ? 48 ILE I C 1 ATOM 5348 O O . ILE D 2 61 ? 72.416 25.822 -7.777 1.00 33.55 ? 48 ILE I O 1 ATOM 5349 C CB . ILE D 2 61 ? 73.384 24.412 -10.557 1.00 30.77 ? 48 ILE I CB 1 ATOM 5350 C CG1 . ILE D 2 61 ? 74.371 24.365 -11.722 1.00 29.94 ? 48 ILE I CG1 1 ATOM 5351 C CG2 . ILE D 2 61 ? 72.270 25.351 -10.920 1.00 31.03 ? 48 ILE I CG2 1 ATOM 5352 C CD1 . ILE D 2 61 ? 73.764 23.807 -13.005 1.00 25.03 ? 48 ILE I CD1 1 ATOM 5353 N N . GLY D 2 62 ? 72.806 23.611 -7.654 1.00 30.82 ? 49 GLY I N 1 ATOM 5354 C CA . GLY D 2 62 ? 71.837 23.449 -6.590 1.00 31.08 ? 49 GLY I CA 1 ATOM 5355 C C . GLY D 2 62 ? 71.531 22.012 -6.238 1.00 30.71 ? 49 GLY I C 1 ATOM 5356 O O . GLY D 2 62 ? 71.845 21.104 -6.988 1.00 30.56 ? 49 GLY I O 1 ATOM 5357 N N . SER D 2 63 ? 70.916 21.798 -5.086 1.00 30.56 ? 50 SER I N 1 ATOM 5358 C CA . SER D 2 63 ? 70.580 20.451 -4.690 1.00 33.02 ? 50 SER I CA 1 ATOM 5359 C C . SER D 2 63 ? 69.135 20.359 -4.250 1.00 32.41 ? 50 SER I C 1 ATOM 5360 O O . SER D 2 63 ? 68.535 21.359 -3.891 1.00 33.11 ? 50 SER I O 1 ATOM 5361 C CB . SER D 2 63 ? 71.505 20.003 -3.574 1.00 36.90 ? 50 SER I CB 1 ATOM 5362 O OG . SER D 2 63 ? 72.700 19.484 -4.120 1.00 42.24 ? 50 SER I OG 1 ATOM 5363 N N . ILE D 2 64 ? 68.570 19.161 -4.289 1.00 31.29 ? 51 ILE I N 1 ATOM 5364 C CA . ILE D 2 64 ? 67.182 18.984 -3.889 1.00 31.60 ? 51 ILE I CA 1 ATOM 5365 C C . ILE D 2 64 ? 66.960 17.625 -3.267 1.00 32.63 ? 51 ILE I C 1 ATOM 5366 O O . ILE D 2 64 ? 67.657 16.659 -3.589 1.00 33.32 ? 51 ILE I O 1 ATOM 5367 C CB . ILE D 2 64 ? 66.218 19.131 -5.073 1.00 32.16 ? 51 ILE I CB 1 ATOM 5368 C CG1 . ILE D 2 64 ? 64.776 19.037 -4.569 1.00 31.39 ? 51 ILE I CG1 1 ATOM 5369 C CG2 . ILE D 2 64 ? 66.510 18.069 -6.128 1.00 29.66 ? 51 ILE I CG2 1 ATOM 5370 C CD1 . ILE D 2 64 ? 63.727 19.099 -5.670 1.00 27.78 ? 51 ILE I CD1 1 ATOM 5371 N N . TYR D 2 65 ? 65.974 17.567 -2.379 1.00 31.42 ? 52 TYR I N 1 ATOM 5372 C CA . TYR D 2 65 ? 65.633 16.357 -1.645 1.00 31.17 ? 52 TYR I CA 1 ATOM 5373 C C . TYR D 2 65 ? 64.304 15.892 -2.219 1.00 32.25 ? 52 TYR I C 1 ATOM 5374 O O . TYR D 2 65 ? 63.506 16.717 -2.642 1.00 32.93 ? 52 TYR I O 1 ATOM 5375 C CB . TYR D 2 65 ? 65.538 16.726 -0.165 1.00 29.05 ? 52 TYR I CB 1 ATOM 5376 C CG . TYR D 2 65 ? 65.319 15.595 0.792 1.00 29.48 ? 52 TYR I CG 1 ATOM 5377 C CD1 . TYR D 2 65 ? 64.066 15.359 1.339 1.00 30.57 ? 52 TYR I CD1 1 ATOM 5378 C CD2 . TYR D 2 65 ? 66.362 14.750 1.149 1.00 31.79 ? 52 TYR I CD2 1 ATOM 5379 C CE1 . TYR D 2 65 ? 63.852 14.307 2.221 1.00 32.41 ? 52 TYR I CE1 1 ATOM 5380 C CE2 . TYR D 2 65 ? 66.157 13.684 2.026 1.00 32.09 ? 52 TYR I CE2 1 ATOM 5381 C CZ . TYR D 2 65 ? 64.901 13.471 2.553 1.00 32.85 ? 52 TYR I CZ 1 ATOM 5382 O OH . TYR D 2 65 ? 64.688 12.399 3.376 1.00 34.15 ? 52 TYR I OH 1 ATOM 5383 N N . TYR D 2 66 ? 64.061 14.587 -2.251 1.00 33.09 ? 53 TYR I N 1 ATOM 5384 C CA . TYR D 2 66 ? 62.817 14.075 -2.830 1.00 36.45 ? 53 TYR I CA 1 ATOM 5385 C C . TYR D 2 66 ? 61.545 14.761 -2.301 1.00 37.22 ? 53 TYR I C 1 ATOM 5386 O O . TYR D 2 66 ? 60.595 15.013 -3.038 1.00 36.68 ? 53 TYR I O 1 ATOM 5387 C CB . TYR D 2 66 ? 62.703 12.551 -2.614 1.00 36.72 ? 53 TYR I CB 1 ATOM 5388 C CG . TYR D 2 66 ? 62.096 12.157 -1.284 1.00 37.56 ? 53 TYR I CG 1 ATOM 5389 C CD1 . TYR D 2 66 ? 62.831 12.263 -0.104 1.00 37.17 ? 53 TYR I CD1 1 ATOM 5390 C CD2 . TYR D 2 66 ? 60.757 11.753 -1.195 1.00 35.49 ? 53 TYR I CD2 1 ATOM 5391 C CE1 . TYR D 2 66 ? 62.250 11.983 1.127 1.00 36.27 ? 53 TYR I CE1 1 ATOM 5392 C CE2 . TYR D 2 66 ? 60.173 11.480 0.032 1.00 34.12 ? 53 TYR I CE2 1 ATOM 5393 C CZ . TYR D 2 66 ? 60.928 11.601 1.188 1.00 35.81 ? 53 TYR I CZ 1 ATOM 5394 O OH . TYR D 2 66 ? 60.364 11.381 2.420 1.00 38.42 ? 53 TYR I OH 1 ATOM 5395 N N . SER D 2 67 ? 61.543 15.059 -1.014 1.00 39.10 ? 54 SER I N 1 ATOM 5396 C CA . SER D 2 67 ? 60.409 15.683 -0.365 1.00 40.86 ? 54 SER I CA 1 ATOM 5397 C C . SER D 2 67 ? 60.120 17.053 -0.947 1.00 41.83 ? 54 SER I C 1 ATOM 5398 O O . SER D 2 67 ? 59.104 17.677 -0.626 1.00 39.99 ? 54 SER I O 1 ATOM 5399 C CB . SER D 2 67 ? 60.695 15.790 1.127 1.00 43.01 ? 54 SER I CB 1 ATOM 5400 O OG . SER D 2 67 ? 59.644 16.444 1.794 1.00 49.73 ? 54 SER I OG 1 ATOM 5401 N N . GLY D 2 68 ? 61.026 17.521 -1.799 1.00 43.49 ? 55 GLY I N 1 ATOM 5402 C CA . GLY D 2 68 ? 60.844 18.816 -2.428 1.00 45.72 ? 55 GLY I CA 1 ATOM 5403 C C . GLY D 2 68 ? 61.726 19.968 -1.961 1.00 46.86 ? 55 GLY I C 1 ATOM 5404 O O . GLY D 2 68 ? 61.890 20.935 -2.702 1.00 46.39 ? 55 GLY I O 1 ATOM 5405 N N . ASN D 2 69 ? 62.296 19.888 -0.759 1.00 47.86 ? 56 ASN I N 1 ATOM 5406 C CA . ASN D 2 69 ? 63.146 20.974 -0.264 1.00 49.97 ? 56 ASN I CA 1 ATOM 5407 C C . ASN D 2 69 ? 64.446 21.117 -1.054 1.00 49.29 ? 56 ASN I C 1 ATOM 5408 O O . ASN D 2 69 ? 65.037 20.114 -1.452 1.00 49.30 ? 56 ASN I O 1 ATOM 5409 C CB . ASN D 2 69 ? 63.491 20.763 1.203 1.00 53.25 ? 56 ASN I CB 1 ATOM 5410 C CG . ASN D 2 69 ? 64.295 21.907 1.765 1.00 56.51 ? 56 ASN I CG 1 ATOM 5411 O OD1 . ASN D 2 69 ? 65.152 21.713 2.622 1.00 58.33 ? 56 ASN I OD1 1 ATOM 5412 N ND2 . ASN D 2 69 ? 64.016 23.120 1.285 1.00 59.35 ? 56 ASN I ND2 1 ATOM 5413 N N . THR D 2 70 ? 64.905 22.356 -1.253 1.00 48.38 ? 57 THR I N 1 ATOM 5414 C CA . THR D 2 70 ? 66.123 22.599 -2.029 1.00 48.73 ? 57 THR I CA 1 ATOM 5415 C C . THR D 2 70 ? 67.068 23.758 -1.672 1.00 48.23 ? 57 THR I C 1 ATOM 5416 O O . THR D 2 70 ? 66.681 24.719 -1.020 1.00 50.95 ? 57 THR I O 1 ATOM 5417 C CB . THR D 2 70 ? 65.778 22.762 -3.503 1.00 49.14 ? 57 THR I CB 1 ATOM 5418 O OG1 . THR D 2 70 ? 66.782 23.574 -4.126 1.00 50.69 ? 57 THR I OG1 1 ATOM 5419 C CG2 . THR D 2 70 ? 64.410 23.408 -3.665 1.00 49.26 ? 57 THR I CG2 1 ATOM 5420 N N . TYR D 2 71 ? 68.310 23.645 -2.141 1.00 47.53 ? 58 TYR I N 1 ATOM 5421 C CA . TYR D 2 71 ? 69.370 24.635 -1.936 1.00 47.52 ? 58 TYR I CA 1 ATOM 5422 C C . TYR D 2 71 ? 69.956 25.022 -3.288 1.00 48.29 ? 58 TYR I C 1 ATOM 5423 O O . TYR D 2 71 ? 70.212 24.150 -4.121 1.00 48.88 ? 58 TYR I O 1 ATOM 5424 C CB . TYR D 2 71 ? 70.506 24.058 -1.092 1.00 48.42 ? 58 TYR I CB 1 ATOM 5425 C CG . TYR D 2 71 ? 70.101 23.676 0.297 1.00 52.49 ? 58 TYR I CG 1 ATOM 5426 C CD1 . TYR D 2 71 ? 69.173 22.652 0.516 1.00 54.27 ? 58 TYR I CD1 1 ATOM 5427 C CD2 . TYR D 2 71 ? 70.588 24.379 1.400 1.00 54.63 ? 58 TYR I CD2 1 ATOM 5428 C CE1 . TYR D 2 71 ? 68.727 22.344 1.797 1.00 56.16 ? 58 TYR I CE1 1 ATOM 5429 C CE2 . TYR D 2 71 ? 70.148 24.080 2.693 1.00 57.72 ? 58 TYR I CE2 1 ATOM 5430 C CZ . TYR D 2 71 ? 69.209 23.066 2.879 1.00 58.51 ? 58 TYR I CZ 1 ATOM 5431 O OH . TYR D 2 71 ? 68.709 22.819 4.138 1.00 62.44 ? 58 TYR I OH 1 ATOM 5432 N N . PHE D 2 72 ? 70.181 26.316 -3.506 1.00 47.74 ? 59 PHE I N 1 ATOM 5433 C CA . PHE D 2 72 ? 70.746 26.778 -4.766 1.00 47.81 ? 59 PHE I CA 1 ATOM 5434 C C . PHE D 2 72 ? 71.973 27.612 -4.516 1.00 50.21 ? 59 PHE I C 1 ATOM 5435 O O . PHE D 2 72 ? 72.135 28.196 -3.450 1.00 50.55 ? 59 PHE I O 1 ATOM 5436 C CB . PHE D 2 72 ? 69.774 27.665 -5.541 1.00 46.08 ? 59 PHE I CB 1 ATOM 5437 C CG . PHE D 2 72 ? 68.334 27.296 -5.380 1.00 46.20 ? 59 PHE I CG 1 ATOM 5438 C CD1 . PHE D 2 72 ? 67.652 27.597 -4.206 1.00 45.58 ? 59 PHE I CD1 1 ATOM 5439 C CD2 . PHE D 2 72 ? 67.645 26.674 -6.416 1.00 44.08 ? 59 PHE I CD2 1 ATOM 5440 C CE1 . PHE D 2 72 ? 66.308 27.286 -4.072 1.00 44.42 ? 59 PHE I CE1 1 ATOM 5441 C CE2 . PHE D 2 72 ? 66.309 26.362 -6.290 1.00 43.21 ? 59 PHE I CE2 1 ATOM 5442 C CZ . PHE D 2 72 ? 65.637 26.667 -5.119 1.00 43.95 ? 59 PHE I CZ 1 ATOM 5443 N N . ASN D 2 73 ? 72.841 27.680 -5.512 1.00 52.66 ? 60 ASN I N 1 ATOM 5444 C CA . ASN D 2 73 ? 74.021 28.506 -5.384 1.00 54.98 ? 60 ASN I CA 1 ATOM 5445 C C . ASN D 2 73 ? 73.433 29.899 -5.490 1.00 56.30 ? 60 ASN I C 1 ATOM 5446 O O . ASN D 2 73 ? 72.794 30.224 -6.487 1.00 56.99 ? 60 ASN I O 1 ATOM 5447 C CB . ASN D 2 73 ? 74.971 28.265 -6.546 1.00 56.72 ? 60 ASN I CB 1 ATOM 5448 C CG . ASN D 2 73 ? 76.235 29.067 -6.426 1.00 59.25 ? 60 ASN I CG 1 ATOM 5449 O OD1 . ASN D 2 73 ? 76.196 30.277 -6.194 1.00 61.80 ? 60 ASN I OD1 1 ATOM 5450 N ND2 . ASN D 2 73 ? 77.373 28.402 -6.583 1.00 60.12 ? 60 ASN I ND2 1 ATOM 5451 N N . PRO D 2 74 ? 73.633 30.739 -4.466 1.00 57.49 ? 61 PRO I N 1 ATOM 5452 C CA . PRO D 2 74 ? 73.113 32.114 -4.442 1.00 57.69 ? 61 PRO I CA 1 ATOM 5453 C C . PRO D 2 74 ? 73.466 32.948 -5.673 1.00 57.32 ? 61 PRO I C 1 ATOM 5454 O O . PRO D 2 74 ? 72.722 33.856 -6.053 1.00 57.87 ? 61 PRO I O 1 ATOM 5455 C CB . PRO D 2 74 ? 73.720 32.690 -3.170 1.00 57.12 ? 61 PRO I CB 1 ATOM 5456 C CG . PRO D 2 74 ? 75.029 31.980 -3.100 1.00 59.16 ? 61 PRO I CG 1 ATOM 5457 C CD . PRO D 2 74 ? 74.625 30.548 -3.399 1.00 58.53 ? 61 PRO I CD 1 ATOM 5458 N N . SER D 2 75 ? 74.595 32.640 -6.303 1.00 56.30 ? 62 SER I N 1 ATOM 5459 C CA . SER D 2 75 ? 75.011 33.381 -7.489 1.00 55.03 ? 62 SER I CA 1 ATOM 5460 C C . SER D 2 75 ? 74.051 33.218 -8.674 1.00 53.77 ? 62 SER I C 1 ATOM 5461 O O . SER D 2 75 ? 74.278 33.797 -9.731 1.00 54.97 ? 62 SER I O 1 ATOM 5462 C CB . SER D 2 75 ? 76.415 32.950 -7.915 1.00 54.21 ? 62 SER I CB 1 ATOM 5463 O OG . SER D 2 75 ? 76.400 31.663 -8.501 1.00 56.81 ? 62 SER I OG 1 ATOM 5464 N N . LEU D 2 76 ? 72.986 32.437 -8.513 1.00 51.76 ? 63 LEU I N 1 ATOM 5465 C CA . LEU D 2 76 ? 72.050 32.248 -9.612 1.00 50.24 ? 63 LEU I CA 1 ATOM 5466 C C . LEU D 2 76 ? 70.702 31.599 -9.273 1.00 50.67 ? 63 LEU I C 1 ATOM 5467 O O . LEU D 2 76 ? 70.054 31.001 -10.135 1.00 48.94 ? 63 LEU I O 1 ATOM 5468 C CB . LEU D 2 76 ? 72.747 31.477 -10.741 1.00 50.05 ? 63 LEU I CB 1 ATOM 5469 C CG . LEU D 2 76 ? 73.551 30.200 -10.490 1.00 47.11 ? 63 LEU I CG 1 ATOM 5470 C CD1 . LEU D 2 76 ? 72.626 29.081 -10.069 1.00 49.60 ? 63 LEU I CD1 1 ATOM 5471 C CD2 . LEU D 2 76 ? 74.276 29.806 -11.756 1.00 43.80 ? 63 LEU I CD2 1 ATOM 5472 N N . LYS D 2 77 ? 70.266 31.749 -8.026 1.00 51.10 ? 64 LYS I N 1 ATOM 5473 C CA . LYS D 2 77 ? 68.997 31.180 -7.593 1.00 50.93 ? 64 LYS I CA 1 ATOM 5474 C C . LYS D 2 77 ? 67.814 31.904 -8.207 1.00 49.07 ? 64 LYS I C 1 ATOM 5475 O O . LYS D 2 77 ? 66.683 31.430 -8.145 1.00 47.57 ? 64 LYS I O 1 ATOM 5476 C CB . LYS D 2 77 ? 68.898 31.225 -6.070 1.00 53.33 ? 64 LYS I CB 1 ATOM 5477 C CG . LYS D 2 77 ? 69.296 32.553 -5.474 1.00 59.12 ? 64 LYS I CG 1 ATOM 5478 C CD . LYS D 2 77 ? 69.442 32.463 -3.951 1.00 63.28 ? 64 LYS I CD 1 ATOM 5479 C CE . LYS D 2 77 ? 69.896 33.800 -3.353 1.00 63.36 ? 64 LYS I CE 1 ATOM 5480 N NZ . LYS D 2 77 ? 70.193 33.692 -1.897 1.00 64.83 ? 64 LYS I NZ 1 ATOM 5481 N N . SER D 2 78 ? 68.082 33.050 -8.813 1.00 48.84 ? 65 SER I N 1 ATOM 5482 C CA . SER D 2 78 ? 67.026 33.841 -9.423 1.00 50.06 ? 65 SER I CA 1 ATOM 5483 C C . SER D 2 78 ? 66.487 33.227 -10.706 1.00 49.98 ? 65 SER I C 1 ATOM 5484 O O . SER D 2 78 ? 65.302 33.364 -11.023 1.00 50.22 ? 65 SER I O 1 ATOM 5485 C CB . SER D 2 78 ? 67.540 35.250 -9.702 1.00 51.05 ? 65 SER I CB 1 ATOM 5486 O OG . SER D 2 78 ? 68.112 35.796 -8.527 1.00 54.10 ? 65 SER I OG 1 ATOM 5487 N N . ARG D 2 79 ? 67.356 32.539 -11.439 1.00 50.09 ? 66 ARG I N 1 ATOM 5488 C CA . ARG D 2 79 ? 66.970 31.922 -12.708 1.00 48.59 ? 66 ARG I CA 1 ATOM 5489 C C . ARG D 2 79 ? 66.946 30.398 -12.610 1.00 46.77 ? 66 ARG I C 1 ATOM 5490 O O . ARG D 2 79 ? 66.586 29.711 -13.572 1.00 47.10 ? 66 ARG I O 1 ATOM 5491 C CB . ARG D 2 79 ? 67.968 32.316 -13.795 1.00 49.80 ? 66 ARG I CB 1 ATOM 5492 C CG . ARG D 2 79 ? 68.609 33.682 -13.598 1.00 50.97 ? 66 ARG I CG 1 ATOM 5493 C CD . ARG D 2 79 ? 70.072 33.639 -13.988 1.00 50.26 ? 66 ARG I CD 1 ATOM 5494 N NE . ARG D 2 79 ? 70.245 33.045 -15.310 1.00 51.00 ? 66 ARG I NE 1 ATOM 5495 C CZ . ARG D 2 79 ? 71.410 32.629 -15.796 1.00 49.80 ? 66 ARG I CZ 1 ATOM 5496 N NH1 . ARG D 2 79 ? 72.517 32.747 -15.065 1.00 47.72 ? 66 ARG I NH1 1 ATOM 5497 N NH2 . ARG D 2 79 ? 71.459 32.079 -17.003 1.00 47.59 ? 66 ARG I NH2 1 ATOM 5498 N N . VAL D 2 80 ? 67.325 29.878 -11.448 1.00 42.93 ? 67 VAL I N 1 ATOM 5499 C CA . VAL D 2 80 ? 67.393 28.440 -11.243 1.00 40.35 ? 67 VAL I CA 1 ATOM 5500 C C . VAL D 2 80 ? 66.172 27.774 -10.647 1.00 39.20 ? 67 VAL I C 1 ATOM 5501 O O . VAL D 2 80 ? 65.505 28.313 -9.781 1.00 38.49 ? 67 VAL I O 1 ATOM 5502 C CB . VAL D 2 80 ? 68.641 28.075 -10.373 1.00 39.79 ? 67 VAL I CB 1 ATOM 5503 C CG1 . VAL D 2 80 ? 68.362 26.885 -9.488 1.00 38.53 ? 67 VAL I CG1 1 ATOM 5504 C CG2 . VAL D 2 80 ? 69.804 27.745 -11.269 1.00 38.78 ? 67 VAL I CG2 1 ATOM 5505 N N . THR D 2 81 ? 65.896 26.579 -11.137 1.00 38.97 ? 68 THR I N 1 ATOM 5506 C CA . THR D 2 81 ? 64.799 25.778 -10.633 1.00 39.92 ? 68 THR I CA 1 ATOM 5507 C C . THR D 2 81 ? 65.213 24.338 -10.727 1.00 40.14 ? 68 THR I C 1 ATOM 5508 O O . THR D 2 81 ? 65.777 23.902 -11.735 1.00 39.50 ? 68 THR I O 1 ATOM 5509 C CB . THR D 2 81 ? 63.524 25.936 -11.438 1.00 40.50 ? 68 THR I CB 1 ATOM 5510 O OG1 . THR D 2 81 ? 62.908 27.174 -11.087 1.00 41.69 ? 68 THR I OG1 1 ATOM 5511 C CG2 . THR D 2 81 ? 62.560 24.783 -11.134 1.00 39.72 ? 68 THR I CG2 1 ATOM 5512 N N . ILE D 2 82 ? 64.925 23.603 -9.665 1.00 39.38 ? 69 ILE I N 1 ATOM 5513 C CA . ILE D 2 82 ? 65.264 22.194 -9.605 1.00 38.97 ? 69 ILE I CA 1 ATOM 5514 C C . ILE D 2 82 ? 64.025 21.521 -9.070 1.00 38.34 ? 69 ILE I C 1 ATOM 5515 O O . ILE D 2 82 ? 63.380 22.041 -8.168 1.00 40.89 ? 69 ILE I O 1 ATOM 5516 C CB . ILE D 2 82 ? 66.450 21.965 -8.651 1.00 38.89 ? 69 ILE I CB 1 ATOM 5517 C CG1 . ILE D 2 82 ? 67.595 22.907 -9.030 1.00 37.60 ? 69 ILE I CG1 1 ATOM 5518 C CG2 . ILE D 2 82 ? 66.917 20.524 -8.727 1.00 39.72 ? 69 ILE I CG2 1 ATOM 5519 C CD1 . ILE D 2 82 ? 68.742 22.865 -8.082 1.00 38.98 ? 69 ILE I CD1 1 ATOM 5520 N N . SER D 2 83 ? 63.664 20.379 -9.627 1.00 36.31 ? 70 SER I N 1 ATOM 5521 C CA . SER D 2 83 ? 62.474 19.711 -9.148 1.00 35.99 ? 70 SER I CA 1 ATOM 5522 C C . SER D 2 83 ? 62.639 18.215 -9.272 1.00 36.38 ? 70 SER I C 1 ATOM 5523 O O . SER D 2 83 ? 63.523 17.747 -9.990 1.00 36.70 ? 70 SER I O 1 ATOM 5524 C CB . SER D 2 83 ? 61.258 20.178 -9.946 1.00 36.11 ? 70 SER I CB 1 ATOM 5525 O OG . SER D 2 83 ? 61.465 20.029 -11.345 1.00 38.56 ? 70 SER I OG 1 ATOM 5526 N N . VAL D 2 84 ? 61.805 17.462 -8.565 1.00 35.13 ? 71 VAL I N 1 ATOM 5527 C CA . VAL D 2 84 ? 61.897 16.026 -8.658 1.00 37.12 ? 71 VAL I CA 1 ATOM 5528 C C . VAL D 2 84 ? 60.559 15.373 -8.964 1.00 38.97 ? 71 VAL I C 1 ATOM 5529 O O . VAL D 2 84 ? 59.510 15.856 -8.553 1.00 40.20 ? 71 VAL I O 1 ATOM 5530 C CB . VAL D 2 84 ? 62.465 15.408 -7.371 1.00 36.96 ? 71 VAL I CB 1 ATOM 5531 C CG1 . VAL D 2 84 ? 61.381 15.229 -6.332 1.00 35.93 ? 71 VAL I CG1 1 ATOM 5532 C CG2 . VAL D 2 84 ? 63.096 14.081 -7.698 1.00 38.17 ? 71 VAL I CG2 1 ATOM 5533 N N . ASP D 2 85 ? 60.610 14.284 -9.717 1.00 39.91 ? 72 ASP I N 1 ATOM 5534 C CA . ASP D 2 85 ? 59.423 13.539 -10.048 1.00 41.69 ? 72 ASP I CA 1 ATOM 5535 C C . ASP D 2 85 ? 59.627 12.076 -9.699 1.00 43.29 ? 72 ASP I C 1 ATOM 5536 O O . ASP D 2 85 ? 60.059 11.264 -10.535 1.00 41.69 ? 72 ASP I O 1 ATOM 5537 C CB . ASP D 2 85 ? 59.069 13.671 -11.523 1.00 45.17 ? 72 ASP I CB 1 ATOM 5538 C CG . ASP D 2 85 ? 57.901 12.767 -11.921 1.00 49.78 ? 72 ASP I CG 1 ATOM 5539 O OD1 . ASP D 2 85 ? 56.986 12.556 -11.085 1.00 49.46 ? 72 ASP I OD1 1 ATOM 5540 O OD2 . ASP D 2 85 ? 57.898 12.270 -13.070 1.00 51.70 ? 72 ASP I OD2 1 ATOM 5541 N N . THR D 2 86 ? 59.326 11.768 -8.441 1.00 43.54 ? 73 THR I N 1 ATOM 5542 C CA . THR D 2 86 ? 59.414 10.425 -7.893 1.00 44.53 ? 73 THR I CA 1 ATOM 5543 C C . THR D 2 86 ? 58.877 9.375 -8.864 1.00 46.57 ? 73 THR I C 1 ATOM 5544 O O . THR D 2 86 ? 59.592 8.455 -9.269 1.00 45.45 ? 73 THR I O 1 ATOM 5545 C CB . THR D 2 86 ? 58.595 10.352 -6.608 1.00 45.20 ? 73 THR I CB 1 ATOM 5546 O OG1 . THR D 2 86 ? 59.238 11.131 -5.600 1.00 44.90 ? 73 THR I OG1 1 ATOM 5547 C CG2 . THR D 2 86 ? 58.427 8.914 -6.148 1.00 46.85 ? 73 THR I CG2 1 ATOM 5548 N N . SER D 2 87 ? 57.601 9.527 -9.220 1.00 48.90 ? 74 SER I N 1 ATOM 5549 C CA . SER D 2 87 ? 56.903 8.625 -10.135 1.00 49.41 ? 74 SER I CA 1 ATOM 5550 C C . SER D 2 87 ? 57.729 8.160 -11.339 1.00 49.58 ? 74 SER I C 1 ATOM 5551 O O . SER D 2 87 ? 57.424 7.129 -11.929 1.00 48.89 ? 74 SER I O 1 ATOM 5552 C CB . SER D 2 87 ? 55.648 9.310 -10.653 1.00 50.91 ? 74 SER I CB 1 ATOM 5553 O OG . SER D 2 87 ? 55.983 10.221 -11.686 1.00 54.24 ? 74 SER I OG 1 ATOM 5554 N N . LYS D 2 88 ? 58.747 8.934 -11.719 1.00 50.04 ? 75 LYS I N 1 ATOM 5555 C CA . LYS D 2 88 ? 59.614 8.595 -12.852 1.00 50.14 ? 75 LYS I CA 1 ATOM 5556 C C . LYS D 2 88 ? 61.060 8.428 -12.406 1.00 48.31 ? 75 LYS I C 1 ATOM 5557 O O . LYS D 2 88 ? 61.926 8.076 -13.208 1.00 46.92 ? 75 LYS I O 1 ATOM 5558 C CB . LYS D 2 88 ? 59.577 9.693 -13.922 1.00 52.89 ? 75 LYS I CB 1 ATOM 5559 C CG . LYS D 2 88 ? 58.329 9.745 -14.782 1.00 56.29 ? 75 LYS I CG 1 ATOM 5560 C CD . LYS D 2 88 ? 58.349 10.987 -15.672 1.00 60.22 ? 75 LYS I CD 1 ATOM 5561 C CE . LYS D 2 88 ? 57.196 10.998 -16.672 1.00 63.12 ? 75 LYS I CE 1 ATOM 5562 N NZ . LYS D 2 88 ? 55.864 10.748 -16.033 1.00 64.97 ? 75 LYS I NZ 1 ATOM 5563 N N . ASN D 2 89 ? 61.310 8.699 -11.128 1.00 46.60 ? 76 ASN I N 1 ATOM 5564 C CA . ASN D 2 89 ? 62.651 8.619 -10.550 1.00 43.92 ? 76 ASN I CA 1 ATOM 5565 C C . ASN D 2 89 ? 63.614 9.552 -11.282 1.00 42.50 ? 76 ASN I C 1 ATOM 5566 O O . ASN D 2 89 ? 64.691 9.136 -11.723 1.00 39.54 ? 76 ASN I O 1 ATOM 5567 C CB . ASN D 2 89 ? 63.187 7.187 -10.597 1.00 43.15 ? 76 ASN I CB 1 ATOM 5568 C CG . ASN D 2 89 ? 64.361 6.973 -9.652 1.00 43.76 ? 76 ASN I CG 1 ATOM 5569 O OD1 . ASN D 2 89 ? 64.279 7.293 -8.456 1.00 43.18 ? 76 ASN I OD1 1 ATOM 5570 N ND2 . ASN D 2 89 ? 65.456 6.422 -10.176 1.00 40.04 ? 76 ASN I ND2 1 ATOM 5571 N N . GLN D 2 90 ? 63.212 10.816 -11.412 1.00 40.95 ? 77 GLN I N 1 ATOM 5572 C CA . GLN D 2 90 ? 64.044 11.817 -12.072 1.00 40.43 ? 77 GLN I CA 1 ATOM 5573 C C . GLN D 2 90 ? 63.944 13.193 -11.422 1.00 38.69 ? 77 GLN I C 1 ATOM 5574 O O . GLN D 2 90 ? 62.917 13.549 -10.870 1.00 40.39 ? 77 GLN I O 1 ATOM 5575 C CB . GLN D 2 90 ? 63.633 12.002 -13.524 1.00 39.31 ? 77 GLN I CB 1 ATOM 5576 C CG . GLN D 2 90 ? 63.024 10.827 -14.218 1.00 40.39 ? 77 GLN I CG 1 ATOM 5577 C CD . GLN D 2 90 ? 62.591 11.220 -15.625 1.00 42.27 ? 77 GLN I CD 1 ATOM 5578 O OE1 . GLN D 2 90 ? 61.808 12.169 -15.800 1.00 42.46 ? 77 GLN I OE1 1 ATOM 5579 N NE2 . GLN D 2 90 ? 63.109 10.513 -16.633 1.00 35.37 ? 77 GLN I NE2 1 ATOM 5580 N N . PHE D 2 91 ? 65.011 13.972 -11.475 1.00 36.69 ? 78 PHE I N 1 ATOM 5581 C CA . PHE D 2 91 ? 64.916 15.324 -10.959 1.00 36.44 ? 78 PHE I CA 1 ATOM 5582 C C . PHE D 2 91 ? 65.360 16.212 -12.120 1.00 35.44 ? 78 PHE I C 1 ATOM 5583 O O . PHE D 2 91 ? 66.039 15.738 -13.036 1.00 34.94 ? 78 PHE I O 1 ATOM 5584 C CB . PHE D 2 91 ? 65.764 15.533 -9.697 1.00 36.25 ? 78 PHE I CB 1 ATOM 5585 C CG . PHE D 2 91 ? 67.221 15.297 -9.888 1.00 36.10 ? 78 PHE I CG 1 ATOM 5586 C CD1 . PHE D 2 91 ? 67.731 14.015 -9.912 1.00 36.08 ? 78 PHE I CD1 1 ATOM 5587 C CD2 . PHE D 2 91 ? 68.093 16.367 -10.021 1.00 37.51 ? 78 PHE I CD2 1 ATOM 5588 C CE1 . PHE D 2 91 ? 69.096 13.803 -10.063 1.00 37.25 ? 78 PHE I CE1 1 ATOM 5589 C CE2 . PHE D 2 91 ? 69.459 16.164 -10.174 1.00 38.63 ? 78 PHE I CE2 1 ATOM 5590 C CZ . PHE D 2 91 ? 69.961 14.882 -10.194 1.00 37.52 ? 78 PHE I CZ 1 ATOM 5591 N N . SER D 2 92 ? 64.963 17.481 -12.108 1.00 34.16 ? 79 SER I N 1 ATOM 5592 C CA . SER D 2 92 ? 65.293 18.367 -13.219 1.00 33.13 ? 79 SER I CA 1 ATOM 5593 C C . SER D 2 92 ? 65.863 19.728 -12.865 1.00 33.63 ? 79 SER I C 1 ATOM 5594 O O . SER D 2 92 ? 65.869 20.144 -11.707 1.00 34.76 ? 79 SER I O 1 ATOM 5595 C CB . SER D 2 92 ? 64.049 18.585 -14.069 1.00 32.65 ? 79 SER I CB 1 ATOM 5596 O OG . SER D 2 92 ? 63.520 17.359 -14.529 1.00 32.50 ? 79 SER I OG 1 ATOM 5597 N N . LEU D 2 93 ? 66.326 20.419 -13.897 1.00 33.11 ? 80 LEU I N 1 ATOM 5598 C CA . LEU D 2 93 ? 66.889 21.753 -13.763 1.00 34.78 ? 80 LEU I CA 1 ATOM 5599 C C . LEU D 2 93 ? 66.242 22.653 -14.791 1.00 36.18 ? 80 LEU I C 1 ATOM 5600 O O . LEU D 2 93 ? 65.861 22.208 -15.871 1.00 36.18 ? 80 LEU I O 1 ATOM 5601 C CB . LEU D 2 93 ? 68.397 21.749 -14.017 1.00 34.69 ? 80 LEU I CB 1 ATOM 5602 C CG . LEU D 2 93 ? 69.067 23.124 -14.054 1.00 30.85 ? 80 LEU I CG 1 ATOM 5603 C CD1 . LEU D 2 93 ? 69.081 23.717 -12.668 1.00 31.46 ? 80 LEU I CD1 1 ATOM 5604 C CD2 . LEU D 2 93 ? 70.468 22.986 -14.571 1.00 30.90 ? 80 LEU I CD2 1 ATOM 5605 N N . LYS D 2 94 ? 66.142 23.930 -14.455 1.00 38.31 ? 81 LYS I N 1 ATOM 5606 C CA . LYS D 2 94 ? 65.547 24.905 -15.342 1.00 40.45 ? 81 LYS I CA 1 ATOM 5607 C C . LYS D 2 94 ? 66.281 26.212 -15.165 1.00 41.27 ? 81 LYS I C 1 ATOM 5608 O O . LYS D 2 94 ? 66.009 26.965 -14.238 1.00 44.43 ? 81 LYS I O 1 ATOM 5609 C CB . LYS D 2 94 ? 64.071 25.091 -14.992 1.00 44.06 ? 81 LYS I CB 1 ATOM 5610 C CG . LYS D 2 94 ? 63.106 24.647 -16.078 1.00 47.01 ? 81 LYS I CG 1 ATOM 5611 C CD . LYS D 2 94 ? 61.663 24.785 -15.626 1.00 49.30 ? 81 LYS I CD 1 ATOM 5612 C CE . LYS D 2 94 ? 60.715 24.437 -16.769 1.00 53.62 ? 81 LYS I CE 1 ATOM 5613 N NZ . LYS D 2 94 ? 61.030 23.115 -17.407 1.00 53.73 ? 81 LYS I NZ 1 ATOM 5614 N N . LEU D 2 95 ? 67.233 26.479 -16.038 1.00 41.86 ? 82 LEU I N 1 ATOM 5615 C CA . LEU D 2 95 ? 67.984 27.717 -15.959 1.00 43.06 ? 82 LEU I CA 1 ATOM 5616 C C . LEU D 2 95 ? 67.242 28.645 -16.897 1.00 44.31 ? 82 LEU I C 1 ATOM 5617 O O . LEU D 2 95 ? 66.815 28.204 -17.960 1.00 45.42 ? 82 LEU I O 1 ATOM 5618 C CB . LEU D 2 95 ? 69.409 27.484 -16.457 1.00 41.74 ? 82 LEU I CB 1 ATOM 5619 C CG . LEU D 2 95 ? 70.366 28.659 -16.316 1.00 42.35 ? 82 LEU I CG 1 ATOM 5620 C CD1 . LEU D 2 95 ? 70.726 28.864 -14.854 1.00 40.81 ? 82 LEU I CD1 1 ATOM 5621 C CD2 . LEU D 2 95 ? 71.604 28.379 -17.130 1.00 43.42 ? 82 LEU I CD2 1 ATOM 5622 N N . SER D 2 96 A 67.056 29.910 -16.535 1.00 45.45 ? 82 SER I N 1 ATOM 5623 C CA . SER D 2 96 A 66.343 30.796 -17.460 1.00 46.99 ? 82 SER I CA 1 ATOM 5624 C C . SER D 2 96 A 67.108 32.052 -17.851 1.00 46.33 ? 82 SER I C 1 ATOM 5625 O O . SER D 2 96 A 68.103 32.414 -17.210 1.00 45.50 ? 82 SER I O 1 ATOM 5626 C CB . SER D 2 96 A 64.970 31.188 -16.903 1.00 48.04 ? 82 SER I CB 1 ATOM 5627 O OG . SER D 2 96 A 65.090 32.018 -15.765 1.00 52.74 ? 82 SER I OG 1 ATOM 5628 N N . SER D 2 97 B 66.628 32.701 -18.916 1.00 46.13 ? 82 SER I N 1 ATOM 5629 C CA . SER D 2 97 B 67.236 33.925 -19.438 1.00 45.91 ? 82 SER I CA 1 ATOM 5630 C C . SER D 2 97 B 68.733 33.698 -19.548 1.00 44.94 ? 82 SER I C 1 ATOM 5631 O O . SER D 2 97 B 69.528 34.371 -18.892 1.00 45.16 ? 82 SER I O 1 ATOM 5632 C CB . SER D 2 97 B 66.947 35.097 -18.498 1.00 46.27 ? 82 SER I CB 1 ATOM 5633 O OG . SER D 2 97 B 65.557 35.185 -18.228 1.00 47.50 ? 82 SER I OG 1 ATOM 5634 N N . VAL D 2 98 C 69.102 32.736 -20.383 1.00 43.00 ? 82 VAL I N 1 ATOM 5635 C CA . VAL D 2 98 C 70.491 32.377 -20.565 1.00 41.48 ? 82 VAL I CA 1 ATOM 5636 C C . VAL D 2 98 C 71.311 33.310 -21.422 1.00 41.55 ? 82 VAL I C 1 ATOM 5637 O O . VAL D 2 98 C 70.788 34.072 -22.224 1.00 40.27 ? 82 VAL I O 1 ATOM 5638 C CB . VAL D 2 98 C 70.610 30.968 -21.139 1.00 41.22 ? 82 VAL I CB 1 ATOM 5639 C CG1 . VAL D 2 98 C 70.379 29.943 -20.045 1.00 43.56 ? 82 VAL I CG1 1 ATOM 5640 C CG2 . VAL D 2 98 C 69.593 30.778 -22.231 1.00 40.10 ? 82 VAL I CG2 1 ATOM 5641 N N . THR D 2 99 ? 72.620 33.224 -21.212 1.00 43.88 ? 83 THR I N 1 ATOM 5642 C CA . THR D 2 99 ? 73.632 34.004 -21.923 1.00 44.98 ? 83 THR I CA 1 ATOM 5643 C C . THR D 2 99 ? 74.813 33.070 -22.201 1.00 44.29 ? 83 THR I C 1 ATOM 5644 O O . THR D 2 99 ? 75.021 32.097 -21.479 1.00 43.80 ? 83 THR I O 1 ATOM 5645 C CB . THR D 2 99 ? 74.143 35.165 -21.066 1.00 46.69 ? 83 THR I CB 1 ATOM 5646 O OG1 . THR D 2 99 ? 75.169 34.696 -20.177 1.00 49.43 ? 83 THR I OG1 1 ATOM 5647 C CG2 . THR D 2 99 ? 73.012 35.743 -20.249 1.00 47.08 ? 83 THR I CG2 1 ATOM 5648 N N . ALA D 2 100 ? 75.592 33.371 -23.232 1.00 44.81 ? 84 ALA I N 1 ATOM 5649 C CA . ALA D 2 100 ? 76.739 32.536 -23.593 1.00 45.01 ? 84 ALA I CA 1 ATOM 5650 C C . ALA D 2 100 ? 77.433 31.986 -22.356 1.00 44.34 ? 84 ALA I C 1 ATOM 5651 O O . ALA D 2 100 ? 78.005 30.889 -22.376 1.00 44.69 ? 84 ALA I O 1 ATOM 5652 C CB . ALA D 2 100 ? 77.723 33.337 -24.423 1.00 45.39 ? 84 ALA I CB 1 ATOM 5653 N N . ALA D 2 101 ? 77.376 32.755 -21.278 1.00 42.14 ? 85 ALA I N 1 ATOM 5654 C CA . ALA D 2 101 ? 77.995 32.348 -20.032 1.00 41.84 ? 85 ALA I CA 1 ATOM 5655 C C . ALA D 2 101 ? 77.462 31.008 -19.526 1.00 41.41 ? 85 ALA I C 1 ATOM 5656 O O . ALA D 2 101 ? 78.129 30.328 -18.755 1.00 41.57 ? 85 ALA I O 1 ATOM 5657 C CB . ALA D 2 101 ? 77.772 33.418 -18.984 1.00 43.01 ? 85 ALA I CB 1 ATOM 5658 N N . ASP D 2 102 ? 76.262 30.633 -19.960 1.00 40.24 ? 86 ASP I N 1 ATOM 5659 C CA . ASP D 2 102 ? 75.650 29.387 -19.526 1.00 38.65 ? 86 ASP I CA 1 ATOM 5660 C C . ASP D 2 102 ? 75.968 28.218 -20.441 1.00 39.10 ? 86 ASP I C 1 ATOM 5661 O O . ASP D 2 102 ? 75.423 27.127 -20.283 1.00 38.10 ? 86 ASP I O 1 ATOM 5662 C CB . ASP D 2 102 ? 74.149 29.571 -19.421 1.00 39.25 ? 86 ASP I CB 1 ATOM 5663 C CG . ASP D 2 102 ? 73.786 30.797 -18.640 1.00 41.06 ? 86 ASP I CG 1 ATOM 5664 O OD1 . ASP D 2 102 ? 74.298 30.962 -17.508 1.00 40.64 ? 86 ASP I OD1 1 ATOM 5665 O OD2 . ASP D 2 102 ? 72.989 31.602 -19.159 1.00 44.17 ? 86 ASP I OD2 1 ATOM 5666 N N . THR D 2 103 ? 76.834 28.454 -21.419 1.00 40.19 ? 87 THR I N 1 ATOM 5667 C CA . THR D 2 103 ? 77.250 27.388 -22.317 1.00 38.84 ? 87 THR I CA 1 ATOM 5668 C C . THR D 2 103 ? 78.188 26.551 -21.461 1.00 38.23 ? 87 THR I C 1 ATOM 5669 O O . THR D 2 103 ? 79.160 27.071 -20.902 1.00 39.66 ? 87 THR I O 1 ATOM 5670 C CB . THR D 2 103 ? 78.021 27.924 -23.520 1.00 38.34 ? 87 THR I CB 1 ATOM 5671 O OG1 . THR D 2 103 ? 77.152 28.743 -24.319 1.00 39.22 ? 87 THR I OG1 1 ATOM 5672 C CG2 . THR D 2 103 ? 78.557 26.770 -24.344 1.00 36.87 ? 87 THR I CG2 1 ATOM 5673 N N . ALA D 2 104 ? 77.881 25.266 -21.339 1.00 35.55 ? 88 ALA I N 1 ATOM 5674 C CA . ALA D 2 104 ? 78.683 24.379 -20.522 1.00 33.50 ? 88 ALA I CA 1 ATOM 5675 C C . ALA D 2 104 ? 78.248 22.926 -20.657 1.00 33.61 ? 88 ALA I C 1 ATOM 5676 O O . ALA D 2 104 ? 77.471 22.561 -21.539 1.00 34.11 ? 88 ALA I O 1 ATOM 5677 C CB . ALA D 2 104 ? 78.580 24.806 -19.085 1.00 32.10 ? 88 ALA I CB 1 ATOM 5678 N N . VAL D 2 105 ? 78.783 22.087 -19.788 1.00 32.94 ? 89 VAL I N 1 ATOM 5679 C CA . VAL D 2 105 ? 78.417 20.689 -19.779 1.00 34.79 ? 89 VAL I CA 1 ATOM 5680 C C . VAL D 2 105 ? 77.756 20.584 -18.443 1.00 34.60 ? 89 VAL I C 1 ATOM 5681 O O . VAL D 2 105 ? 78.386 20.851 -17.434 1.00 36.90 ? 89 VAL I O 1 ATOM 5682 C CB . VAL D 2 105 ? 79.636 19.754 -19.798 1.00 35.64 ? 89 VAL I CB 1 ATOM 5683 C CG1 . VAL D 2 105 ? 79.216 18.363 -19.381 1.00 34.77 ? 89 VAL I CG1 1 ATOM 5684 C CG2 . VAL D 2 105 ? 80.236 19.706 -21.192 1.00 37.21 ? 89 VAL I CG2 1 ATOM 5685 N N . TYR D 2 106 ? 76.486 20.224 -18.422 1.00 33.94 ? 90 TYR I N 1 ATOM 5686 C CA . TYR D 2 106 ? 75.801 20.130 -17.152 1.00 34.70 ? 90 TYR I CA 1 ATOM 5687 C C . TYR D 2 106 ? 75.839 18.712 -16.605 1.00 35.38 ? 90 TYR I C 1 ATOM 5688 O O . TYR D 2 106 ? 75.627 17.747 -17.330 1.00 37.76 ? 90 TYR I O 1 ATOM 5689 C CB . TYR D 2 106 ? 74.380 20.666 -17.306 1.00 31.50 ? 90 TYR I CB 1 ATOM 5690 C CG . TYR D 2 106 ? 74.377 22.170 -17.534 1.00 30.98 ? 90 TYR I CG 1 ATOM 5691 C CD1 . TYR D 2 106 ? 74.908 22.725 -18.705 1.00 28.26 ? 90 TYR I CD1 1 ATOM 5692 C CD2 . TYR D 2 106 ? 73.883 23.044 -16.561 1.00 28.01 ? 90 TYR I CD2 1 ATOM 5693 C CE1 . TYR D 2 106 ? 74.945 24.104 -18.894 1.00 22.42 ? 90 TYR I CE1 1 ATOM 5694 C CE2 . TYR D 2 106 ? 73.921 24.414 -16.746 1.00 23.81 ? 90 TYR I CE2 1 ATOM 5695 C CZ . TYR D 2 106 ? 74.450 24.933 -17.910 1.00 22.11 ? 90 TYR I CZ 1 ATOM 5696 O OH . TYR D 2 106 ? 74.482 26.289 -18.076 1.00 20.40 ? 90 TYR I OH 1 ATOM 5697 N N . TYR D 2 107 ? 76.141 18.597 -15.322 1.00 34.30 ? 91 TYR I N 1 ATOM 5698 C CA . TYR D 2 107 ? 76.251 17.305 -14.672 1.00 34.86 ? 91 TYR I CA 1 ATOM 5699 C C . TYR D 2 107 ? 75.199 17.130 -13.603 1.00 36.27 ? 91 TYR I C 1 ATOM 5700 O O . TYR D 2 107 ? 74.874 18.082 -12.906 1.00 37.03 ? 91 TYR I O 1 ATOM 5701 C CB . TYR D 2 107 ? 77.611 17.190 -13.973 1.00 34.64 ? 91 TYR I CB 1 ATOM 5702 C CG . TYR D 2 107 ? 78.819 17.092 -14.874 1.00 34.72 ? 91 TYR I CG 1 ATOM 5703 C CD1 . TYR D 2 107 ? 79.070 15.937 -15.615 1.00 35.11 ? 91 TYR I CD1 1 ATOM 5704 C CD2 . TYR D 2 107 ? 79.731 18.132 -14.957 1.00 33.19 ? 91 TYR I CD2 1 ATOM 5705 C CE1 . TYR D 2 107 ? 80.194 15.825 -16.409 1.00 33.46 ? 91 TYR I CE1 1 ATOM 5706 C CE2 . TYR D 2 107 ? 80.860 18.026 -15.745 1.00 33.58 ? 91 TYR I CE2 1 ATOM 5707 C CZ . TYR D 2 107 ? 81.083 16.869 -16.465 1.00 34.41 ? 91 TYR I CZ 1 ATOM 5708 O OH . TYR D 2 107 ? 82.208 16.749 -17.238 1.00 38.10 ? 91 TYR I OH 1 ATOM 5709 N N . CYS D 2 108 ? 74.656 15.926 -13.472 1.00 36.64 ? 92 CYS I N 1 ATOM 5710 C CA . CYS D 2 108 ? 73.737 15.678 -12.375 1.00 38.61 ? 92 CYS I CA 1 ATOM 5711 C C . CYS D 2 108 ? 74.429 14.644 -11.521 1.00 38.82 ? 92 CYS I C 1 ATOM 5712 O O . CYS D 2 108 ? 75.026 13.714 -12.055 1.00 40.33 ? 92 CYS I O 1 ATOM 5713 C CB . CYS D 2 108 ? 72.355 15.195 -12.830 1.00 40.40 ? 92 CYS I CB 1 ATOM 5714 S SG . CYS D 2 108 ? 72.110 13.727 -13.881 1.00 43.85 ? 92 CYS I SG 1 ATOM 5715 N N . ALA D 2 109 ? 74.384 14.813 -10.203 1.00 37.74 ? 93 ALA I N 1 ATOM 5716 C CA . ALA D 2 109 ? 75.065 13.879 -9.317 1.00 37.42 ? 93 ALA I CA 1 ATOM 5717 C C . ALA D 2 109 ? 74.316 13.623 -8.038 1.00 37.91 ? 93 ALA I C 1 ATOM 5718 O O . ALA D 2 109 ? 73.287 14.232 -7.785 1.00 39.94 ? 93 ALA I O 1 ATOM 5719 C CB . ALA D 2 109 ? 76.439 14.403 -8.988 1.00 36.73 ? 93 ALA I CB 1 ATOM 5720 N N . ARG D 2 110 ? 74.836 12.707 -7.232 1.00 37.84 ? 94 ARG I N 1 ATOM 5721 C CA . ARG D 2 110 ? 74.222 12.404 -5.955 1.00 39.58 ? 94 ARG I CA 1 ATOM 5722 C C . ARG D 2 110 ? 75.083 12.989 -4.855 1.00 41.55 ? 94 ARG I C 1 ATOM 5723 O O . ARG D 2 110 ? 76.275 12.706 -4.764 1.00 43.62 ? 94 ARG I O 1 ATOM 5724 C CB . ARG D 2 110 ? 74.094 10.902 -5.735 1.00 39.00 ? 94 ARG I CB 1 ATOM 5725 C CG . ARG D 2 110 ? 73.545 10.562 -4.361 1.00 37.18 ? 94 ARG I CG 1 ATOM 5726 C CD . ARG D 2 110 ? 73.299 9.082 -4.206 1.00 40.46 ? 94 ARG I CD 1 ATOM 5727 N NE . ARG D 2 110 ? 74.362 8.380 -3.483 1.00 41.78 ? 94 ARG I NE 1 ATOM 5728 C CZ . ARG D 2 110 ? 74.245 7.138 -3.021 1.00 40.97 ? 94 ARG I CZ 1 ATOM 5729 N NH1 . ARG D 2 110 ? 73.125 6.463 -3.213 1.00 41.77 ? 94 ARG I NH1 1 ATOM 5730 N NH2 . ARG D 2 110 ? 75.226 6.578 -2.333 1.00 42.60 ? 94 ARG I NH2 1 ATOM 5731 N N . LEU D 2 111 ? 74.478 13.805 -4.009 1.00 42.88 ? 95 LEU I N 1 ATOM 5732 C CA . LEU D 2 111 ? 75.222 14.413 -2.934 1.00 44.13 ? 95 LEU I CA 1 ATOM 5733 C C . LEU D 2 111 ? 75.865 13.432 -1.969 1.00 46.31 ? 95 LEU I C 1 ATOM 5734 O O . LEU D 2 111 ? 75.227 12.474 -1.503 1.00 42.91 ? 95 LEU I O 1 ATOM 5735 C CB . LEU D 2 111 ? 74.337 15.391 -2.170 1.00 44.68 ? 95 LEU I CB 1 ATOM 5736 C CG . LEU D 2 111 ? 74.288 16.801 -2.757 1.00 46.52 ? 95 LEU I CG 1 ATOM 5737 C CD1 . LEU D 2 111 ? 75.483 17.601 -2.246 1.00 46.32 ? 95 LEU I CD1 1 ATOM 5738 C CD2 . LEU D 2 111 ? 74.260 16.734 -4.285 1.00 45.04 ? 95 LEU I CD2 1 ATOM 5739 N N . GLY D 2 112 ? 77.149 13.733 -1.715 1.00 49.71 ? 96 GLY I N 1 ATOM 5740 C CA . GLY D 2 112 ? 78.064 13.029 -0.826 1.00 50.55 ? 96 GLY I CA 1 ATOM 5741 C C . GLY D 2 112 ? 77.861 11.558 -0.636 1.00 51.95 ? 96 GLY I C 1 ATOM 5742 O O . GLY D 2 112 ? 76.922 11.007 -1.198 1.00 57.45 ? 96 GLY I O 1 ATOM 5743 N N . PRO D 2 113 ? 78.748 10.874 0.107 1.00 49.95 ? 97 PRO I N 1 ATOM 5744 C CA . PRO D 2 113 ? 78.540 9.438 0.308 1.00 45.96 ? 97 PRO I CA 1 ATOM 5745 C C . PRO D 2 113 ? 77.649 9.240 1.537 1.00 43.37 ? 97 PRO I C 1 ATOM 5746 O O . PRO D 2 113 ? 76.717 8.450 1.503 1.00 41.90 ? 97 PRO I O 1 ATOM 5747 C CB . PRO D 2 113 ? 79.955 8.911 0.493 1.00 44.69 ? 97 PRO I CB 1 ATOM 5748 C CG . PRO D 2 113 ? 80.607 10.031 1.214 1.00 48.53 ? 97 PRO I CG 1 ATOM 5749 C CD . PRO D 2 113 ? 80.123 11.258 0.467 1.00 49.76 ? 97 PRO I CD 1 ATOM 5750 N N . ASP D 2 114 ? 77.913 9.989 2.606 1.00 43.18 ? 98 ASP I N 1 ATOM 5751 C CA . ASP D 2 114 ? 77.118 9.878 3.836 1.00 45.72 ? 98 ASP I CA 1 ATOM 5752 C C . ASP D 2 114 ? 75.667 10.277 3.605 1.00 45.18 ? 98 ASP I C 1 ATOM 5753 O O . ASP D 2 114 ? 75.343 10.873 2.596 1.00 46.82 ? 98 ASP I O 1 ATOM 5754 C CB . ASP D 2 114 ? 77.703 10.757 4.946 1.00 48.92 ? 98 ASP I CB 1 ATOM 5755 C CG . ASP D 2 114 ? 79.106 10.328 5.366 1.00 50.47 ? 98 ASP I CG 1 ATOM 5756 O OD1 . ASP D 2 114 ? 79.273 9.208 5.900 1.00 48.77 ? 98 ASP I OD1 1 ATOM 5757 O OD2 . ASP D 2 114 ? 80.044 11.124 5.155 1.00 52.92 ? 98 ASP I OD2 1 ATOM 5758 N N . ASP D 2 115 ? 74.783 9.954 4.537 1.00 43.84 ? 99 ASP I N 1 ATOM 5759 C CA . ASP D 2 115 ? 73.385 10.305 4.349 1.00 42.51 ? 99 ASP I CA 1 ATOM 5760 C C . ASP D 2 115 ? 73.177 11.783 4.649 1.00 42.26 ? 99 ASP I C 1 ATOM 5761 O O . ASP D 2 115 ? 73.802 12.338 5.550 1.00 42.23 ? 99 ASP I O 1 ATOM 5762 C CB . ASP D 2 115 ? 72.491 9.445 5.253 1.00 44.07 ? 99 ASP I CB 1 ATOM 5763 C CG . ASP D 2 115 ? 72.375 8.001 4.769 1.00 48.28 ? 99 ASP I CG 1 ATOM 5764 O OD1 . ASP D 2 115 ? 73.228 7.558 3.958 1.00 50.65 ? 99 ASP I OD1 1 ATOM 5765 O OD2 . ASP D 2 115 ? 71.434 7.296 5.207 1.00 50.16 ? 99 ASP I OD2 1 ATOM 5766 N N . TYR D 2 116 ? 72.300 12.414 3.878 1.00 40.78 ? 100 TYR I N 1 ATOM 5767 C CA . TYR D 2 116 ? 71.976 13.826 4.037 1.00 39.54 ? 100 TYR I CA 1 ATOM 5768 C C . TYR D 2 116 ? 73.182 14.741 3.839 1.00 39.95 ? 100 TYR I C 1 ATOM 5769 O O . TYR D 2 116 ? 73.242 15.843 4.382 1.00 40.12 ? 100 TYR I O 1 ATOM 5770 C CB . TYR D 2 116 ? 71.339 14.062 5.409 1.00 37.56 ? 100 TYR I CB 1 ATOM 5771 C CG . TYR D 2 116 ? 70.271 13.054 5.727 1.00 37.52 ? 100 TYR I CG 1 ATOM 5772 C CD1 . TYR D 2 116 ? 70.501 12.047 6.653 1.00 37.73 ? 100 TYR I CD1 1 ATOM 5773 C CD2 . TYR D 2 116 ? 69.056 13.056 5.046 1.00 38.55 ? 100 TYR I CD2 1 ATOM 5774 C CE1 . TYR D 2 116 ? 69.554 11.059 6.900 1.00 38.59 ? 100 TYR I CE1 1 ATOM 5775 C CE2 . TYR D 2 116 ? 68.097 12.069 5.275 1.00 38.67 ? 100 TYR I CE2 1 ATOM 5776 C CZ . TYR D 2 116 ? 68.356 11.070 6.208 1.00 40.14 ? 100 TYR I CZ 1 ATOM 5777 O OH . TYR D 2 116 ? 67.440 10.068 6.436 1.00 38.27 ? 100 TYR I OH 1 ATOM 5778 N N . THR D 2 117 A 74.139 14.285 3.042 1.00 39.78 ? 100 THR I N 1 ATOM 5779 C CA . THR D 2 117 A 75.333 15.068 2.758 1.00 39.49 ? 100 THR I CA 1 ATOM 5780 C C . THR D 2 117 A 74.954 16.184 1.818 1.00 40.12 ? 100 THR I C 1 ATOM 5781 O O . THR D 2 117 A 74.232 15.951 0.850 1.00 40.91 ? 100 THR I O 1 ATOM 5782 C CB . THR D 2 117 A 76.389 14.223 2.072 1.00 39.47 ? 100 THR I CB 1 ATOM 5783 O OG1 . THR D 2 117 A 76.953 13.316 3.026 1.00 41.25 ? 100 THR I OG1 1 ATOM 5784 C CG2 . THR D 2 117 A 77.463 15.106 1.477 1.00 38.97 ? 100 THR I CG2 1 ATOM 5785 N N . LEU D 2 118 B 75.446 17.390 2.085 1.00 39.61 ? 100 LEU I N 1 ATOM 5786 C CA . LEU D 2 118 B 75.124 18.528 1.236 1.00 38.81 ? 100 LEU I CA 1 ATOM 5787 C C . LEU D 2 118 B 76.305 19.193 0.568 1.00 40.09 ? 100 LEU I C 1 ATOM 5788 O O . LEU D 2 118 B 76.119 20.102 -0.236 1.00 42.14 ? 100 LEU I O 1 ATOM 5789 C CB . LEU D 2 118 B 74.342 19.585 2.026 1.00 36.09 ? 100 LEU I CB 1 ATOM 5790 C CG . LEU D 2 118 B 72.839 19.332 2.173 1.00 33.80 ? 100 LEU I CG 1 ATOM 5791 C CD1 . LEU D 2 118 B 72.173 20.462 2.915 1.00 31.91 ? 100 LEU I CD1 1 ATOM 5792 C CD2 . LEU D 2 118 B 72.229 19.201 0.798 1.00 34.32 ? 100 LEU I CD2 1 ATOM 5793 N N . ASP D 2 119 C 77.514 18.734 0.871 1.00 41.75 ? 100 ASP I N 1 ATOM 5794 C CA . ASP D 2 119 C 78.712 19.344 0.307 1.00 42.36 ? 100 ASP I CA 1 ATOM 5795 C C . ASP D 2 119 C 79.557 18.513 -0.660 1.00 42.79 ? 100 ASP I C 1 ATOM 5796 O O . ASP D 2 119 C 80.482 19.041 -1.276 1.00 44.91 ? 100 ASP I O 1 ATOM 5797 C CB . ASP D 2 119 C 79.578 19.859 1.450 1.00 43.70 ? 100 ASP I CB 1 ATOM 5798 C CG . ASP D 2 119 C 79.675 18.867 2.596 1.00 48.23 ? 100 ASP I CG 1 ATOM 5799 O OD1 . ASP D 2 119 C 79.530 19.278 3.777 1.00 48.20 ? 100 ASP I OD1 1 ATOM 5800 O OD2 . ASP D 2 119 C 79.901 17.670 2.312 1.00 49.43 ? 100 ASP I OD2 1 ATOM 5801 N N . GLY D 2 120 D 79.257 17.227 -0.806 1.00 41.86 ? 100 GLY I N 1 ATOM 5802 C CA . GLY D 2 120 D 80.026 16.412 -1.733 1.00 41.52 ? 100 GLY I CA 1 ATOM 5803 C C . GLY D 2 120 D 79.124 15.745 -2.753 1.00 42.51 ? 100 GLY I C 1 ATOM 5804 O O . GLY D 2 120 D 77.913 15.855 -2.656 1.00 46.50 ? 100 GLY I O 1 ATOM 5805 N N . MET D 2 121 E 79.684 15.088 -3.757 1.00 41.54 ? 100 MET I N 1 ATOM 5806 C CA . MET D 2 121 E 78.862 14.393 -4.740 1.00 41.38 ? 100 MET I CA 1 ATOM 5807 C C . MET D 2 121 E 79.634 13.122 -4.941 1.00 41.65 ? 100 MET I C 1 ATOM 5808 O O . MET D 2 121 E 80.821 13.185 -5.229 1.00 42.70 ? 100 MET I O 1 ATOM 5809 C CB . MET D 2 121 E 78.803 15.131 -6.078 1.00 42.47 ? 100 MET I CB 1 ATOM 5810 C CG . MET D 2 121 E 79.312 16.556 -6.086 1.00 46.78 ? 100 MET I CG 1 ATOM 5811 S SD . MET D 2 121 E 78.138 17.791 -5.505 1.00 49.18 ? 100 MET I SD 1 ATOM 5812 C CE . MET D 2 121 E 79.044 18.482 -4.143 1.00 50.49 ? 100 MET I CE 1 ATOM 5813 N N . ASP D 2 122 ? 78.994 11.969 -4.796 1.00 41.68 ? 101 ASP I N 1 ATOM 5814 C CA . ASP D 2 122 ? 79.733 10.726 -4.967 1.00 41.51 ? 101 ASP I CA 1 ATOM 5815 C C . ASP D 2 122 ? 79.501 10.018 -6.289 1.00 40.73 ? 101 ASP I C 1 ATOM 5816 O O . ASP D 2 122 ? 80.414 9.419 -6.830 1.00 42.73 ? 101 ASP I O 1 ATOM 5817 C CB . ASP D 2 122 ? 79.469 9.768 -3.802 1.00 43.22 ? 101 ASP I CB 1 ATOM 5818 C CG . ASP D 2 122 ? 78.026 9.339 -3.703 1.00 43.28 ? 101 ASP I CG 1 ATOM 5819 O OD1 . ASP D 2 122 ? 77.384 9.112 -4.746 1.00 44.16 ? 101 ASP I OD1 1 ATOM 5820 O OD2 . ASP D 2 122 ? 77.543 9.201 -2.569 1.00 42.01 ? 101 ASP I OD2 1 ATOM 5821 N N . VAL D 2 123 ? 78.290 10.078 -6.814 1.00 40.04 ? 102 VAL I N 1 ATOM 5822 C CA . VAL D 2 123 ? 78.007 9.454 -8.101 1.00 41.01 ? 102 VAL I CA 1 ATOM 5823 C C . VAL D 2 123 ? 77.692 10.579 -9.093 1.00 40.92 ? 102 VAL I C 1 ATOM 5824 O O . VAL D 2 123 ? 76.814 11.401 -8.836 1.00 44.35 ? 102 VAL I O 1 ATOM 5825 C CB . VAL D 2 123 ? 76.784 8.493 -8.022 1.00 40.53 ? 102 VAL I CB 1 ATOM 5826 C CG1 . VAL D 2 123 ? 76.522 7.873 -9.372 1.00 41.62 ? 102 VAL I CG1 1 ATOM 5827 C CG2 . VAL D 2 123 ? 77.035 7.407 -7.015 1.00 39.48 ? 102 VAL I CG2 1 ATOM 5828 N N . TRP D 2 124 ? 78.405 10.631 -10.211 1.00 38.04 ? 103 TRP I N 1 ATOM 5829 C CA . TRP D 2 124 ? 78.151 11.664 -11.205 1.00 36.64 ? 103 TRP I CA 1 ATOM 5830 C C . TRP D 2 124 ? 77.567 11.066 -12.461 1.00 37.58 ? 103 TRP I C 1 ATOM 5831 O O . TRP D 2 124 ? 77.800 9.908 -12.771 1.00 39.73 ? 103 TRP I O 1 ATOM 5832 C CB . TRP D 2 124 ? 79.436 12.379 -11.585 1.00 34.27 ? 103 TRP I CB 1 ATOM 5833 C CG . TRP D 2 124 ? 80.046 13.130 -10.482 1.00 34.31 ? 103 TRP I CG 1 ATOM 5834 C CD1 . TRP D 2 124 ? 80.458 12.638 -9.281 1.00 33.17 ? 103 TRP I CD1 1 ATOM 5835 C CD2 . TRP D 2 124 ? 80.318 14.529 -10.461 1.00 34.90 ? 103 TRP I CD2 1 ATOM 5836 N NE1 . TRP D 2 124 ? 80.972 13.648 -8.510 1.00 33.78 ? 103 TRP I NE1 1 ATOM 5837 C CE2 . TRP D 2 124 ? 80.898 14.822 -9.214 1.00 35.14 ? 103 TRP I CE2 1 ATOM 5838 C CE3 . TRP D 2 124 ? 80.124 15.570 -11.379 1.00 34.75 ? 103 TRP I CE3 1 ATOM 5839 C CZ2 . TRP D 2 124 ? 81.288 16.112 -8.859 1.00 35.98 ? 103 TRP I CZ2 1 ATOM 5840 C CZ3 . TRP D 2 124 ? 80.510 16.852 -11.026 1.00 34.33 ? 103 TRP I CZ3 1 ATOM 5841 C CH2 . TRP D 2 124 ? 81.085 17.112 -9.779 1.00 35.61 ? 103 TRP I CH2 1 ATOM 5842 N N . GLY D 2 125 ? 76.796 11.859 -13.183 1.00 38.61 ? 104 GLY I N 1 ATOM 5843 C CA . GLY D 2 125 ? 76.230 11.381 -14.423 1.00 39.54 ? 104 GLY I CA 1 ATOM 5844 C C . GLY D 2 125 ? 77.353 11.544 -15.418 1.00 41.62 ? 104 GLY I C 1 ATOM 5845 O O . GLY D 2 125 ? 78.456 11.930 -15.040 1.00 40.58 ? 104 GLY I O 1 ATOM 5846 N N . GLN D 2 126 ? 77.080 11.274 -16.686 1.00 45.05 ? 105 GLN I N 1 ATOM 5847 C CA . GLN D 2 126 ? 78.102 11.377 -17.714 1.00 48.85 ? 105 GLN I CA 1 ATOM 5848 C C . GLN D 2 126 ? 78.281 12.813 -18.189 1.00 48.79 ? 105 GLN I C 1 ATOM 5849 O O . GLN D 2 126 ? 79.358 13.200 -18.637 1.00 50.23 ? 105 GLN I O 1 ATOM 5850 C CB . GLN D 2 126 ? 77.725 10.483 -18.895 1.00 53.91 ? 105 GLN I CB 1 ATOM 5851 C CG . GLN D 2 126 ? 78.814 10.325 -19.958 1.00 61.76 ? 105 GLN I CG 1 ATOM 5852 C CD . GLN D 2 126 ? 78.312 9.601 -21.214 1.00 64.61 ? 105 GLN I CD 1 ATOM 5853 O OE1 . GLN D 2 126 ? 77.687 8.536 -21.127 1.00 65.50 ? 105 GLN I OE1 1 ATOM 5854 N NE2 . GLN D 2 126 ? 78.593 10.178 -22.386 1.00 64.53 ? 105 GLN I NE2 1 ATOM 5855 N N . GLY D 2 127 ? 77.223 13.605 -18.079 1.00 48.73 ? 106 GLY I N 1 ATOM 5856 C CA . GLY D 2 127 ? 77.283 14.983 -18.530 1.00 47.41 ? 106 GLY I CA 1 ATOM 5857 C C . GLY D 2 127 ? 76.489 15.150 -19.813 1.00 47.31 ? 106 GLY I C 1 ATOM 5858 O O . GLY D 2 127 ? 76.191 14.170 -20.498 1.00 47.86 ? 106 GLY I O 1 ATOM 5859 N N . THR D 2 128 ? 76.130 16.387 -20.132 1.00 47.09 ? 107 THR I N 1 ATOM 5860 C CA . THR D 2 128 ? 75.372 16.706 -21.344 1.00 47.64 ? 107 THR I CA 1 ATOM 5861 C C . THR D 2 128 ? 75.896 18.071 -21.760 1.00 46.99 ? 107 THR I C 1 ATOM 5862 O O . THR D 2 128 ? 76.083 18.937 -20.907 1.00 46.90 ? 107 THR I O 1 ATOM 5863 C CB . THR D 2 128 ? 73.837 16.778 -21.048 1.00 48.40 ? 107 THR I CB 1 ATOM 5864 O OG1 . THR D 2 128 ? 73.115 17.108 -22.241 1.00 48.48 ? 107 THR I OG1 1 ATOM 5865 C CG2 . THR D 2 128 ? 73.546 17.819 -19.987 1.00 48.29 ? 107 THR I CG2 1 ATOM 5866 N N . THR D 2 129 ? 76.163 18.270 -23.046 1.00 46.22 ? 108 THR I N 1 ATOM 5867 C CA . THR D 2 129 ? 76.691 19.565 -23.472 1.00 47.05 ? 108 THR I CA 1 ATOM 5868 C C . THR D 2 129 ? 75.590 20.527 -23.873 1.00 47.43 ? 108 THR I C 1 ATOM 5869 O O . THR D 2 129 ? 74.622 20.143 -24.533 1.00 49.16 ? 108 THR I O 1 ATOM 5870 C CB . THR D 2 129 ? 77.664 19.440 -24.669 1.00 47.90 ? 108 THR I CB 1 ATOM 5871 O OG1 . THR D 2 129 ? 78.729 18.545 -24.333 1.00 48.63 ? 108 THR I OG1 1 ATOM 5872 C CG2 . THR D 2 129 ? 78.258 20.810 -25.023 1.00 46.30 ? 108 THR I CG2 1 ATOM 5873 N N . VAL D 2 130 ? 75.736 21.782 -23.471 1.00 46.59 ? 109 VAL I N 1 ATOM 5874 C CA . VAL D 2 130 ? 74.746 22.779 -23.818 1.00 45.75 ? 109 VAL I CA 1 ATOM 5875 C C . VAL D 2 130 ? 75.436 24.005 -24.344 1.00 46.02 ? 109 VAL I C 1 ATOM 5876 O O . VAL D 2 130 ? 76.169 24.662 -23.624 1.00 46.75 ? 109 VAL I O 1 ATOM 5877 C CB . VAL D 2 130 ? 73.886 23.179 -22.616 1.00 45.37 ? 109 VAL I CB 1 ATOM 5878 C CG1 . VAL D 2 130 ? 72.895 24.262 -23.032 1.00 44.56 ? 109 VAL I CG1 1 ATOM 5879 C CG2 . VAL D 2 130 ? 73.143 21.965 -22.081 1.00 42.88 ? 109 VAL I CG2 1 ATOM 5880 N N . THR D 2 131 ? 75.208 24.298 -25.615 1.00 47.99 ? 110 THR I N 1 ATOM 5881 C CA . THR D 2 131 ? 75.799 25.466 -26.243 1.00 50.21 ? 110 THR I CA 1 ATOM 5882 C C . THR D 2 131 ? 74.700 26.510 -26.392 1.00 51.28 ? 110 THR I C 1 ATOM 5883 O O . THR D 2 131 ? 73.662 26.243 -27.000 1.00 52.99 ? 110 THR I O 1 ATOM 5884 C CB . THR D 2 131 ? 76.366 25.134 -27.642 1.00 49.84 ? 110 THR I CB 1 ATOM 5885 O OG1 . THR D 2 131 ? 77.258 24.016 -27.554 1.00 50.52 ? 110 THR I OG1 1 ATOM 5886 C CG2 . THR D 2 131 ? 77.128 26.317 -28.188 1.00 48.79 ? 110 THR I CG2 1 ATOM 5887 N N . VAL D 2 132 ? 74.912 27.686 -25.819 1.00 51.58 ? 111 VAL I N 1 ATOM 5888 C CA . VAL D 2 132 ? 73.929 28.747 -25.917 1.00 54.04 ? 111 VAL I CA 1 ATOM 5889 C C . VAL D 2 132 ? 74.228 29.584 -27.152 1.00 57.21 ? 111 VAL I C 1 ATOM 5890 O O . VAL D 2 132 ? 75.128 30.424 -27.143 1.00 57.95 ? 111 VAL I O 1 ATOM 5891 C CB . VAL D 2 132 ? 73.960 29.649 -24.671 1.00 54.15 ? 111 VAL I CB 1 ATOM 5892 C CG1 . VAL D 2 132 ? 73.267 30.964 -24.955 1.00 55.07 ? 111 VAL I CG1 1 ATOM 5893 C CG2 . VAL D 2 132 ? 73.256 28.963 -23.528 1.00 54.25 ? 111 VAL I CG2 1 ATOM 5894 N N . SER D 2 133 ? 73.482 29.337 -28.222 1.00 60.31 ? 112 SER I N 1 ATOM 5895 C CA . SER D 2 133 ? 73.663 30.081 -29.464 1.00 62.66 ? 112 SER I CA 1 ATOM 5896 C C . SER D 2 133 ? 72.357 30.675 -29.944 1.00 64.67 ? 112 SER I C 1 ATOM 5897 O O . SER D 2 133 ? 71.282 30.257 -29.522 1.00 65.57 ? 112 SER I O 1 ATOM 5898 C CB . SER D 2 133 ? 74.208 29.186 -30.563 1.00 62.20 ? 112 SER I CB 1 ATOM 5899 O OG . SER D 2 133 ? 74.174 29.883 -31.792 1.00 62.08 ? 112 SER I OG 1 ATOM 5900 N N . SER D 2 134 ? 72.453 31.640 -30.849 1.00 66.48 ? 113 SER I N 1 ATOM 5901 C CA . SER D 2 134 ? 71.262 32.293 -31.378 1.00 68.16 ? 113 SER I CA 1 ATOM 5902 C C . SER D 2 134 ? 71.013 31.959 -32.843 1.00 68.40 ? 113 SER I C 1 ATOM 5903 O O . SER D 2 134 ? 70.107 32.512 -33.457 1.00 67.33 ? 113 SER I O 1 ATOM 5904 C CB . SER D 2 134 ? 71.404 33.804 -31.211 1.00 67.39 ? 113 SER I CB 1 ATOM 5905 O OG . SER D 2 134 ? 72.712 34.199 -31.568 1.00 69.24 ? 113 SER I OG 1 ATOM 5906 N N . GLY D 2 135 ? 71.800 31.030 -33.383 1.00 69.59 ? 114 GLY I N 1 ATOM 5907 C CA . GLY D 2 135 ? 71.669 30.674 -34.783 1.00 70.79 ? 114 GLY I CA 1 ATOM 5908 C C . GLY D 2 135 ? 71.120 29.318 -35.181 1.00 71.92 ? 114 GLY I C 1 ATOM 5909 O O . GLY D 2 135 ? 71.143 28.978 -36.365 1.00 72.24 ? 114 GLY I O 1 ATOM 5910 N N . SER D 2 136 ? 70.634 28.538 -34.223 1.00 73.17 ? 115 SER I N 1 ATOM 5911 C CA . SER D 2 136 ? 70.060 27.219 -34.525 1.00 75.66 ? 115 SER I CA 1 ATOM 5912 C C . SER D 2 136 ? 70.960 26.306 -35.356 1.00 76.55 ? 115 SER I C 1 ATOM 5913 O O . SER D 2 136 ? 71.827 26.769 -36.102 1.00 76.31 ? 115 SER I O 1 ATOM 5914 C CB . SER D 2 136 ? 68.730 27.368 -35.272 1.00 76.28 ? 115 SER I CB 1 ATOM 5915 O OG . SER D 2 136 ? 68.950 27.686 -36.639 1.00 75.71 ? 115 SER I OG 1 ATOM 5916 N N . ALA D 2 137 ? 70.720 25.001 -35.232 1.00 77.08 ? 116 ALA I N 1 ATOM 5917 C CA . ALA D 2 137 ? 71.481 23.984 -35.954 1.00 77.09 ? 116 ALA I CA 1 ATOM 5918 C C . ALA D 2 137 ? 71.727 24.371 -37.406 1.00 77.23 ? 116 ALA I C 1 ATOM 5919 O O . ALA D 2 137 ? 71.079 25.268 -37.938 1.00 77.13 ? 116 ALA I O 1 ATOM 5920 C CB . ALA D 2 137 ? 70.750 22.662 -35.895 1.00 77.10 ? 116 ALA I CB 1 ATOM 5921 N N . SER D 2 138 ? 72.667 23.685 -38.045 1.00 77.57 ? 117 SER I N 1 ATOM 5922 C CA . SER D 2 138 ? 72.986 23.974 -39.431 1.00 78.22 ? 117 SER I CA 1 ATOM 5923 C C . SER D 2 138 ? 74.052 23.035 -39.944 1.00 78.90 ? 117 SER I C 1 ATOM 5924 O O . SER D 2 138 ? 74.384 22.050 -39.294 1.00 78.94 ? 117 SER I O 1 ATOM 5925 C CB . SER D 2 138 ? 73.469 25.416 -39.572 1.00 77.89 ? 117 SER I CB 1 ATOM 5926 O OG . SER D 2 138 ? 74.633 25.635 -38.806 1.00 76.86 ? 117 SER I OG 1 ATOM 5927 N N . ALA D 2 139 ? 74.575 23.348 -41.125 1.00 80.60 ? 118 ALA I N 1 ATOM 5928 C CA . ALA D 2 139 ? 75.618 22.544 -41.744 1.00 82.32 ? 118 ALA I CA 1 ATOM 5929 C C . ALA D 2 139 ? 76.805 23.442 -42.064 1.00 83.65 ? 118 ALA I C 1 ATOM 5930 O O . ALA D 2 139 ? 76.641 24.629 -42.379 1.00 82.43 ? 118 ALA I O 1 ATOM 5931 C CB . ALA D 2 139 ? 75.103 21.878 -43.011 1.00 81.98 ? 118 ALA I CB 1 ATOM 5932 N N . PRO D 2 140 ? 78.019 22.873 -42.003 1.00 84.85 ? 119 PRO I N 1 ATOM 5933 C CA . PRO D 2 140 ? 79.290 23.555 -42.261 1.00 85.85 ? 119 PRO I CA 1 ATOM 5934 C C . PRO D 2 140 ? 79.563 23.926 -43.709 1.00 87.51 ? 119 PRO I C 1 ATOM 5935 O O . PRO D 2 140 ? 79.301 23.141 -44.620 1.00 88.01 ? 119 PRO I O 1 ATOM 5936 C CB . PRO D 2 140 ? 80.313 22.556 -41.749 1.00 85.09 ? 119 PRO I CB 1 ATOM 5937 C CG . PRO D 2 140 ? 79.693 21.255 -42.155 1.00 84.99 ? 119 PRO I CG 1 ATOM 5938 C CD . PRO D 2 140 ? 78.242 21.434 -41.759 1.00 84.14 ? 119 PRO I CD 1 ATOM 5939 N N . THR D 2 141 ? 80.086 25.131 -43.914 1.00 88.92 ? 120 THR I N 1 ATOM 5940 C CA . THR D 2 141 ? 80.457 25.575 -45.250 1.00 90.13 ? 120 THR I CA 1 ATOM 5941 C C . THR D 2 141 ? 81.944 25.236 -45.294 1.00 90.74 ? 120 THR I C 1 ATOM 5942 O O . THR D 2 141 ? 82.662 25.492 -44.331 1.00 90.18 ? 120 THR I O 1 ATOM 5943 C CB . THR D 2 141 ? 80.249 27.097 -45.438 1.00 90.47 ? 120 THR I CB 1 ATOM 5944 O OG1 . THR D 2 141 ? 81.046 27.814 -44.491 1.00 91.79 ? 120 THR I OG1 1 ATOM 5945 C CG2 . THR D 2 141 ? 78.783 27.469 -45.239 1.00 90.34 ? 120 THR I CG2 1 ATOM 5946 N N . LEU D 2 142 ? 82.404 24.640 -46.388 1.00 92.51 ? 121 LEU I N 1 ATOM 5947 C CA . LEU D 2 142 ? 83.805 24.248 -46.491 1.00 95.11 ? 121 LEU I CA 1 ATOM 5948 C C . LEU D 2 142 ? 84.657 25.151 -47.379 1.00 96.97 ? 121 LEU I C 1 ATOM 5949 O O . LEU D 2 142 ? 84.203 25.625 -48.423 1.00 97.56 ? 121 LEU I O 1 ATOM 5950 C CB . LEU D 2 142 ? 83.895 22.808 -46.990 1.00 95.15 ? 121 LEU I CB 1 ATOM 5951 C CG . LEU D 2 142 ? 83.059 21.787 -46.218 1.00 95.62 ? 121 LEU I CG 1 ATOM 5952 C CD1 . LEU D 2 142 ? 83.253 20.414 -46.832 1.00 95.52 ? 121 LEU I CD1 1 ATOM 5953 C CD2 . LEU D 2 142 ? 83.467 21.783 -44.753 1.00 96.64 ? 121 LEU I CD2 1 ATOM 5954 N N . PHE D 2 143 ? 85.895 25.388 -46.948 1.00 98.63 ? 122 PHE I N 1 ATOM 5955 C CA . PHE D 2 143 ? 86.836 26.230 -47.687 1.00 100.83 ? 122 PHE I CA 1 ATOM 5956 C C . PHE D 2 143 ? 88.224 25.585 -47.753 1.00 101.61 ? 122 PHE I C 1 ATOM 5957 O O . PHE D 2 143 ? 88.722 25.058 -46.759 1.00 102.44 ? 122 PHE I O 1 ATOM 5958 C CB . PHE D 2 143 ? 86.950 27.607 -47.026 1.00 101.78 ? 122 PHE I CB 1 ATOM 5959 C CG . PHE D 2 143 ? 85.702 28.433 -47.123 1.00 103.71 ? 122 PHE I CG 1 ATOM 5960 C CD1 . PHE D 2 143 ? 84.506 27.985 -46.570 1.00 104.39 ? 122 PHE I CD1 1 ATOM 5961 C CD2 . PHE D 2 143 ? 85.717 29.660 -47.774 1.00 104.43 ? 122 PHE I CD2 1 ATOM 5962 C CE1 . PHE D 2 143 ? 83.339 28.744 -46.664 1.00 105.20 ? 122 PHE I CE1 1 ATOM 5963 C CE2 . PHE D 2 143 ? 84.556 30.429 -47.874 1.00 105.46 ? 122 PHE I CE2 1 ATOM 5964 C CZ . PHE D 2 143 ? 83.365 29.969 -47.318 1.00 105.86 ? 122 PHE I CZ 1 ATOM 5965 N N . PRO D 2 144 ? 88.868 25.620 -48.930 1.00 101.75 ? 123 PRO I N 1 ATOM 5966 C CA . PRO D 2 144 ? 90.199 25.028 -49.084 1.00 101.89 ? 123 PRO I CA 1 ATOM 5967 C C . PRO D 2 144 ? 91.322 25.906 -48.531 1.00 102.25 ? 123 PRO I C 1 ATOM 5968 O O . PRO D 2 144 ? 91.312 27.124 -48.703 1.00 102.24 ? 123 PRO I O 1 ATOM 5969 C CB . PRO D 2 144 ? 90.303 24.838 -50.591 1.00 101.82 ? 123 PRO I CB 1 ATOM 5970 C CG . PRO D 2 144 ? 89.589 26.040 -51.108 1.00 101.62 ? 123 PRO I CG 1 ATOM 5971 C CD . PRO D 2 144 ? 88.355 26.094 -50.228 1.00 101.53 ? 123 PRO I CD 1 ATOM 5972 N N . LEU D 2 145 ? 92.286 25.283 -47.863 1.00 103.00 ? 124 LEU I N 1 ATOM 5973 C CA . LEU D 2 145 ? 93.417 26.014 -47.307 1.00 104.32 ? 124 LEU I CA 1 ATOM 5974 C C . LEU D 2 145 ? 94.693 25.649 -48.054 1.00 105.99 ? 124 LEU I C 1 ATOM 5975 O O . LEU D 2 145 ? 95.274 24.590 -47.828 1.00 106.45 ? 124 LEU I O 1 ATOM 5976 C CB . LEU D 2 145 ? 93.578 25.708 -45.816 1.00 102.89 ? 124 LEU I CB 1 ATOM 5977 C CG . LEU D 2 145 ? 92.514 26.274 -44.870 1.00 102.20 ? 124 LEU I CG 1 ATOM 5978 C CD1 . LEU D 2 145 ? 92.923 26.020 -43.427 1.00 101.06 ? 124 LEU I CD1 1 ATOM 5979 C CD2 . LEU D 2 145 ? 92.359 27.768 -45.111 1.00 101.61 ? 124 LEU I CD2 1 ATOM 5980 N N . VAL D 2 146 ? 95.115 26.537 -48.948 1.00 108.07 ? 125 VAL I N 1 ATOM 5981 C CA . VAL D 2 146 ? 96.313 26.338 -49.759 1.00 110.00 ? 125 VAL I CA 1 ATOM 5982 C C . VAL D 2 146 ? 97.561 26.011 -48.941 1.00 111.53 ? 125 VAL I C 1 ATOM 5983 O O . VAL D 2 146 ? 97.630 24.961 -48.306 1.00 112.35 ? 125 VAL I O 1 ATOM 5984 C CB . VAL D 2 146 ? 96.599 27.582 -50.625 1.00 110.32 ? 125 VAL I CB 1 ATOM 5985 C CG1 . VAL D 2 146 ? 95.496 27.757 -51.663 1.00 110.73 ? 125 VAL I CG1 1 ATOM 5986 C CG2 . VAL D 2 146 ? 96.696 28.820 -49.742 1.00 110.01 ? 125 VAL I CG2 1 ATOM 5987 N N . SER D 2 147 ? 98.549 26.903 -48.970 1.00 112.83 ? 126 SER I N 1 ATOM 5988 C CA . SER D 2 147 ? 99.795 26.696 -48.234 1.00 114.11 ? 126 SER I CA 1 ATOM 5989 C C . SER D 2 147 ? 100.702 27.930 -48.268 1.00 115.04 ? 126 SER I C 1 ATOM 5990 O O . SER D 2 147 ? 101.397 28.233 -47.292 1.00 114.84 ? 126 SER I O 1 ATOM 5991 C CB . SER D 2 147 ? 100.547 25.491 -48.809 1.00 113.71 ? 126 SER I CB 1 ATOM 5992 O OG . SER D 2 147 ? 100.800 25.661 -50.194 1.00 113.43 ? 126 SER I OG 1 ATOM 5993 N N . CYS D 2 148 ? 100.692 28.636 -49.395 1.00 115.82 ? 127 CYS I N 1 ATOM 5994 C CA . CYS D 2 148 ? 101.514 29.830 -49.562 1.00 116.12 ? 127 CYS I CA 1 ATOM 5995 C C . CYS D 2 148 ? 100.881 30.782 -50.569 1.00 115.50 ? 127 CYS I C 1 ATOM 5996 O O . CYS D 2 148 ? 99.975 31.540 -50.232 1.00 114.60 ? 127 CYS I O 1 ATOM 5997 C CB . CYS D 2 148 ? 102.920 29.438 -50.032 1.00 116.89 ? 127 CYS I CB 1 ATOM 5998 S SG . CYS D 2 148 ? 104.004 30.827 -50.453 1.00 117.54 ? 127 CYS I SG 1 ATOM 5999 N N . ASP D 2 149 ? 113.995 22.688 -51.106 1.00 134.71 ? 132 ASP I N 1 ATOM 6000 C CA . ASP D 2 149 ? 112.664 22.229 -51.491 1.00 134.94 ? 132 ASP I CA 1 ATOM 6001 C C . ASP D 2 149 ? 111.906 21.744 -50.249 1.00 134.90 ? 132 ASP I C 1 ATOM 6002 O O . ASP D 2 149 ? 112.491 21.602 -49.171 1.00 134.68 ? 132 ASP I O 1 ATOM 6003 C CB . ASP D 2 149 ? 112.781 21.097 -52.521 1.00 134.67 ? 132 ASP I CB 1 ATOM 6004 C CG . ASP D 2 149 ? 111.514 20.913 -53.342 1.00 134.20 ? 132 ASP I CG 1 ATOM 6005 O OD1 . ASP D 2 149 ? 111.131 21.856 -54.072 1.00 133.20 ? 132 ASP I OD1 1 ATOM 6006 O OD2 . ASP D 2 149 ? 110.904 19.825 -53.259 1.00 133.94 ? 132 ASP I OD2 1 ATOM 6007 N N . THR D 2 150 ? 110.607 21.491 -50.402 1.00 134.48 ? 133 THR I N 1 ATOM 6008 C CA . THR D 2 150 ? 109.776 21.037 -49.287 1.00 133.81 ? 133 THR I CA 1 ATOM 6009 C C . THR D 2 150 ? 109.604 19.516 -49.244 1.00 132.77 ? 133 THR I C 1 ATOM 6010 O O . THR D 2 150 ? 108.830 18.946 -50.019 1.00 132.43 ? 133 THR I O 1 ATOM 6011 C CB . THR D 2 150 ? 108.364 21.687 -49.335 1.00 134.24 ? 133 THR I CB 1 ATOM 6012 O OG1 . THR D 2 150 ? 108.488 23.115 -49.333 1.00 134.29 ? 133 THR I OG1 1 ATOM 6013 C CG2 . THR D 2 150 ? 107.533 21.259 -48.126 1.00 134.23 ? 133 THR I CG2 1 ATOM 6014 N N . SER D 2 151 ? 110.329 18.865 -48.337 1.00 131.30 ? 134 SER I N 1 ATOM 6015 C CA . SER D 2 151 ? 110.228 17.419 -48.184 1.00 129.46 ? 134 SER I CA 1 ATOM 6016 C C . SER D 2 151 ? 108.846 17.128 -47.614 1.00 128.17 ? 134 SER I C 1 ATOM 6017 O O . SER D 2 151 ? 108.679 17.009 -46.399 1.00 128.26 ? 134 SER I O 1 ATOM 6018 C CB . SER D 2 151 ? 111.306 16.905 -47.228 1.00 129.54 ? 134 SER I CB 1 ATOM 6019 O OG . SER D 2 151 ? 111.198 15.503 -47.051 1.00 129.29 ? 134 SER I OG 1 ATOM 6020 N N . SER D 2 152 ? 107.863 17.031 -48.505 1.00 126.17 ? 135 SER I N 1 ATOM 6021 C CA . SER D 2 152 ? 106.472 16.779 -48.138 1.00 123.99 ? 135 SER I CA 1 ATOM 6022 C C . SER D 2 152 ? 105.784 18.055 -47.649 1.00 122.15 ? 135 SER I C 1 ATOM 6023 O O . SER D 2 152 ? 105.930 18.449 -46.492 1.00 121.83 ? 135 SER I O 1 ATOM 6024 C CB . SER D 2 152 ? 106.375 15.687 -47.060 1.00 124.04 ? 135 SER I CB 1 ATOM 6025 O OG . SER D 2 152 ? 106.835 14.436 -47.547 1.00 123.63 ? 135 SER I OG 1 ATOM 6026 N N . VAL D 2 153 ? 105.050 18.702 -48.551 1.00 120.21 ? 136 VAL I N 1 ATOM 6027 C CA . VAL D 2 153 ? 104.315 19.923 -48.231 1.00 118.20 ? 136 VAL I CA 1 ATOM 6028 C C . VAL D 2 153 ? 102.881 19.497 -47.908 1.00 116.47 ? 136 VAL I C 1 ATOM 6029 O O . VAL D 2 153 ? 102.551 18.315 -48.026 1.00 116.17 ? 136 VAL I O 1 ATOM 6030 C CB . VAL D 2 153 ? 104.319 20.911 -49.427 1.00 118.47 ? 136 VAL I CB 1 ATOM 6031 C CG1 . VAL D 2 153 ? 103.361 20.432 -50.510 1.00 118.22 ? 136 VAL I CG1 1 ATOM 6032 C CG2 . VAL D 2 153 ? 103.956 22.310 -48.950 1.00 118.81 ? 136 VAL I CG2 1 ATOM 6033 N N . ALA D 2 154 ? 102.024 20.438 -47.514 1.00 114.22 ? 137 ALA I N 1 ATOM 6034 C CA . ALA D 2 154 ? 100.654 20.071 -47.161 1.00 111.81 ? 137 ALA I CA 1 ATOM 6035 C C . ALA D 2 154 ? 99.550 21.075 -47.481 1.00 109.47 ? 137 ALA I C 1 ATOM 6036 O O . ALA D 2 154 ? 99.789 22.275 -47.606 1.00 108.79 ? 137 ALA I O 1 ATOM 6037 C CB . ALA D 2 154 ? 100.597 19.709 -45.678 1.00 112.85 ? 137 ALA I CB 1 ATOM 6038 N N . VAL D 2 155 ? 98.333 20.547 -47.593 1.00 107.27 ? 138 VAL I N 1 ATOM 6039 C CA . VAL D 2 155 ? 97.129 21.323 -47.882 1.00 104.84 ? 138 VAL I CA 1 ATOM 6040 C C . VAL D 2 155 ? 96.066 21.042 -46.816 1.00 102.84 ? 138 VAL I C 1 ATOM 6041 O O . VAL D 2 155 ? 96.100 20.003 -46.154 1.00 102.86 ? 138 VAL I O 1 ATOM 6042 C CB . VAL D 2 155 ? 96.558 20.955 -49.263 1.00 105.02 ? 138 VAL I CB 1 ATOM 6043 C CG1 . VAL D 2 155 ? 97.505 21.430 -50.352 1.00 104.70 ? 138 VAL I CG1 1 ATOM 6044 C CG2 . VAL D 2 155 ? 96.356 19.443 -49.359 1.00 103.87 ? 138 VAL I CG2 1 ATOM 6045 N N . GLY D 2 156 ? 95.116 21.957 -46.656 1.00 100.36 ? 139 GLY I N 1 ATOM 6046 C CA . GLY D 2 156 ? 94.093 21.762 -45.643 1.00 97.99 ? 139 GLY I CA 1 ATOM 6047 C C . GLY D 2 156 ? 92.647 21.972 -46.057 1.00 96.01 ? 139 GLY I C 1 ATOM 6048 O O . GLY D 2 156 ? 92.342 22.213 -47.224 1.00 95.61 ? 139 GLY I O 1 ATOM 6049 N N . CYS D 2 157 ? 91.754 21.886 -45.075 1.00 93.82 ? 140 CYS I N 1 ATOM 6050 C CA . CYS D 2 157 ? 90.323 22.047 -45.301 1.00 91.81 ? 140 CYS I CA 1 ATOM 6051 C C . CYS D 2 157 ? 89.669 22.734 -44.117 1.00 90.04 ? 140 CYS I C 1 ATOM 6052 O O . CYS D 2 157 ? 89.759 22.263 -42.987 1.00 90.75 ? 140 CYS I O 1 ATOM 6053 C CB . CYS D 2 157 ? 89.679 20.681 -45.506 1.00 92.63 ? 140 CYS I CB 1 ATOM 6054 S SG . CYS D 2 157 ? 87.861 20.644 -45.614 1.00 92.49 ? 140 CYS I SG 1 ATOM 6055 N N . LEU D 2 158 ? 88.998 23.845 -44.387 1.00 88.13 ? 141 LEU I N 1 ATOM 6056 C CA . LEU D 2 158 ? 88.324 24.613 -43.350 1.00 85.53 ? 141 LEU I CA 1 ATOM 6057 C C . LEU D 2 158 ? 86.834 24.293 -43.309 1.00 83.89 ? 141 LEU I C 1 ATOM 6058 O O . LEU D 2 158 ? 86.209 24.057 -44.343 1.00 83.51 ? 141 LEU I O 1 ATOM 6059 C CB . LEU D 2 158 ? 88.527 26.106 -43.612 1.00 85.46 ? 141 LEU I CB 1 ATOM 6060 C CG . LEU D 2 158 ? 87.935 27.113 -42.629 1.00 86.01 ? 141 LEU I CG 1 ATOM 6061 C CD1 . LEU D 2 158 ? 88.494 26.873 -41.236 1.00 87.00 ? 141 LEU I CD1 1 ATOM 6062 C CD2 . LEU D 2 158 ? 88.264 28.522 -43.099 1.00 85.50 ? 141 LEU I CD2 1 ATOM 6063 N N . ALA D 2 159 ? 86.277 24.278 -42.103 1.00 82.31 ? 142 ALA I N 1 ATOM 6064 C CA . ALA D 2 159 ? 84.857 24.004 -41.902 1.00 80.63 ? 142 ALA I CA 1 ATOM 6065 C C . ALA D 2 159 ? 84.295 25.021 -40.918 1.00 79.75 ? 142 ALA I C 1 ATOM 6066 O O . ALA D 2 159 ? 84.697 25.071 -39.754 1.00 78.56 ? 142 ALA I O 1 ATOM 6067 C CB . ALA D 2 159 ? 84.658 22.587 -41.369 1.00 79.86 ? 142 ALA I CB 1 ATOM 6068 N N . GLN D 2 160 ? 83.365 25.839 -41.393 1.00 79.62 ? 143 GLN I N 1 ATOM 6069 C CA . GLN D 2 160 ? 82.763 26.856 -40.547 1.00 79.71 ? 143 GLN I CA 1 ATOM 6070 C C . GLN D 2 160 ? 81.242 26.837 -40.591 1.00 79.05 ? 143 GLN I C 1 ATOM 6071 O O . GLN D 2 160 ? 80.630 26.044 -41.311 1.00 78.36 ? 143 GLN I O 1 ATOM 6072 C CB . GLN D 2 160 ? 83.228 28.241 -40.980 1.00 80.45 ? 143 GLN I CB 1 ATOM 6073 C CG . GLN D 2 160 ? 84.718 28.410 -41.074 1.00 83.00 ? 143 GLN I CG 1 ATOM 6074 C CD . GLN D 2 160 ? 85.094 29.835 -41.418 1.00 84.45 ? 143 GLN I CD 1 ATOM 6075 O OE1 . GLN D 2 160 ? 84.613 30.391 -42.407 1.00 84.52 ? 143 GLN I OE1 1 ATOM 6076 N NE2 . GLN D 2 160 ? 85.957 30.438 -40.601 1.00 86.07 ? 143 GLN I NE2 1 ATOM 6077 N N . ASP D 2 161 ? 80.648 27.719 -39.793 1.00 78.48 ? 144 ASP I N 1 ATOM 6078 C CA . ASP D 2 161 ? 79.207 27.887 -39.736 1.00 77.76 ? 144 ASP I CA 1 ATOM 6079 C C . ASP D 2 161 ? 78.362 26.716 -39.218 1.00 76.61 ? 144 ASP I C 1 ATOM 6080 O O . ASP D 2 161 ? 77.207 26.923 -38.865 1.00 77.04 ? 144 ASP I O 1 ATOM 6081 C CB . ASP D 2 161 ? 78.725 28.338 -41.122 1.00 79.99 ? 144 ASP I CB 1 ATOM 6082 C CG . ASP D 2 161 ? 77.219 28.485 -41.210 1.00 81.84 ? 144 ASP I CG 1 ATOM 6083 O OD1 . ASP D 2 161 ? 76.620 29.075 -40.286 1.00 83.13 ? 144 ASP I OD1 1 ATOM 6084 O OD2 . ASP D 2 161 ? 76.637 28.020 -42.219 1.00 82.75 ? 144 ASP I OD2 1 ATOM 6085 N N . PHE D 2 162 ? 78.902 25.499 -39.159 1.00 75.12 ? 145 PHE I N 1 ATOM 6086 C CA . PHE D 2 162 ? 78.097 24.377 -38.656 1.00 74.46 ? 145 PHE I CA 1 ATOM 6087 C C . PHE D 2 162 ? 77.820 24.591 -37.183 1.00 73.94 ? 145 PHE I C 1 ATOM 6088 O O . PHE D 2 162 ? 78.668 25.112 -36.468 1.00 73.43 ? 145 PHE I O 1 ATOM 6089 C CB . PHE D 2 162 ? 78.800 23.026 -38.857 1.00 74.19 ? 145 PHE I CB 1 ATOM 6090 C CG . PHE D 2 162 ? 80.082 22.867 -38.080 1.00 73.34 ? 145 PHE I CG 1 ATOM 6091 C CD1 . PHE D 2 162 ? 80.272 21.762 -37.263 1.00 72.19 ? 145 PHE I CD1 1 ATOM 6092 C CD2 . PHE D 2 162 ? 81.107 23.799 -38.187 1.00 73.31 ? 145 PHE I CD2 1 ATOM 6093 C CE1 . PHE D 2 162 ? 81.457 21.589 -36.567 1.00 71.76 ? 145 PHE I CE1 1 ATOM 6094 C CE2 . PHE D 2 162 ? 82.295 23.630 -37.493 1.00 72.32 ? 145 PHE I CE2 1 ATOM 6095 C CZ . PHE D 2 162 ? 82.468 22.523 -36.682 1.00 72.15 ? 145 PHE I CZ 1 ATOM 6096 N N . LEU D 2 163 ? 76.646 24.197 -36.709 1.00 74.49 ? 146 LEU I N 1 ATOM 6097 C CA . LEU D 2 163 ? 76.374 24.438 -35.309 1.00 75.83 ? 146 LEU I CA 1 ATOM 6098 C C . LEU D 2 163 ? 76.568 23.244 -34.387 1.00 76.64 ? 146 LEU I C 1 ATOM 6099 O O . LEU D 2 163 ? 77.696 22.998 -33.961 1.00 78.12 ? 146 LEU I O 1 ATOM 6100 C CB . LEU D 2 163 ? 74.991 25.061 -35.113 1.00 76.60 ? 146 LEU I CB 1 ATOM 6101 C CG . LEU D 2 163 ? 75.025 26.123 -34.004 1.00 77.41 ? 146 LEU I CG 1 ATOM 6102 C CD1 . LEU D 2 163 ? 73.681 26.812 -33.878 1.00 77.13 ? 146 LEU I CD1 1 ATOM 6103 C CD2 . LEU D 2 163 ? 75.413 25.472 -32.690 1.00 77.23 ? 146 LEU I CD2 1 ATOM 6104 N N . PRO D 2 164 ? 75.503 22.478 -34.069 1.00 75.51 ? 147 PRO I N 1 ATOM 6105 C CA . PRO D 2 164 ? 75.843 21.373 -33.166 1.00 74.44 ? 147 PRO I CA 1 ATOM 6106 C C . PRO D 2 164 ? 77.129 20.700 -33.631 1.00 75.26 ? 147 PRO I C 1 ATOM 6107 O O . PRO D 2 164 ? 77.185 20.118 -34.714 1.00 76.53 ? 147 PRO I O 1 ATOM 6108 C CB . PRO D 2 164 ? 74.617 20.469 -33.240 1.00 71.88 ? 147 PRO I CB 1 ATOM 6109 C CG . PRO D 2 164 ? 74.114 20.709 -34.603 1.00 73.35 ? 147 PRO I CG 1 ATOM 6110 C CD . PRO D 2 164 ? 74.241 22.197 -34.774 1.00 73.92 ? 147 PRO I CD 1 ATOM 6111 N N . ASP D 2 165 ? 78.175 20.835 -32.821 1.00 75.53 ? 148 ASP I N 1 ATOM 6112 C CA . ASP D 2 165 ? 79.479 20.268 -33.139 1.00 75.77 ? 148 ASP I CA 1 ATOM 6113 C C . ASP D 2 165 ? 79.426 18.748 -33.153 1.00 75.11 ? 148 ASP I C 1 ATOM 6114 O O . ASP D 2 165 ? 79.134 18.119 -32.139 1.00 75.67 ? 148 ASP I O 1 ATOM 6115 C CB . ASP D 2 165 ? 80.522 20.764 -32.128 1.00 75.29 ? 148 ASP I CB 1 ATOM 6116 C CG . ASP D 2 165 ? 81.907 20.208 -32.392 1.00 75.89 ? 148 ASP I CG 1 ATOM 6117 O OD1 . ASP D 2 165 ? 82.882 20.884 -32.005 1.00 76.28 ? 148 ASP I OD1 1 ATOM 6118 O OD2 . ASP D 2 165 ? 82.027 19.099 -32.966 1.00 74.49 ? 148 ASP I OD2 1 ATOM 6119 N N . SER D 2 166 ? 79.709 18.168 -34.314 1.00 74.84 ? 149 SER I N 1 ATOM 6120 C CA . SER D 2 166 ? 79.691 16.722 -34.471 1.00 75.35 ? 149 SER I CA 1 ATOM 6121 C C . SER D 2 166 ? 80.314 16.296 -35.796 1.00 76.06 ? 149 SER I C 1 ATOM 6122 O O . SER D 2 166 ? 80.066 15.183 -36.268 1.00 76.74 ? 149 SER I O 1 ATOM 6123 C CB . SER D 2 166 ? 78.253 16.207 -34.395 1.00 74.47 ? 149 SER I CB 1 ATOM 6124 O OG . SER D 2 166 ? 77.659 16.518 -33.144 1.00 74.28 ? 149 SER I OG 1 ATOM 6125 N N . ILE D 2 167 ? 81.115 17.180 -36.392 1.00 76.07 ? 150 ILE I N 1 ATOM 6126 C CA . ILE D 2 167 ? 81.776 16.893 -37.664 1.00 75.26 ? 150 ILE I CA 1 ATOM 6127 C C . ILE D 2 167 ? 82.602 15.618 -37.596 1.00 75.72 ? 150 ILE I C 1 ATOM 6128 O O . ILE D 2 167 ? 82.759 15.018 -36.531 1.00 76.19 ? 150 ILE I O 1 ATOM 6129 C CB . ILE D 2 167 ? 82.723 18.041 -38.112 1.00 74.80 ? 150 ILE I CB 1 ATOM 6130 C CG1 . ILE D 2 167 ? 83.373 18.695 -36.895 1.00 75.07 ? 150 ILE I CG1 1 ATOM 6131 C CG2 . ILE D 2 167 ? 81.963 19.063 -38.933 1.00 74.70 ? 150 ILE I CG2 1 ATOM 6132 C CD1 . ILE D 2 167 ? 84.067 17.725 -35.971 1.00 76.22 ? 150 ILE I CD1 1 ATOM 6133 N N . THR D 2 168 ? 83.126 15.218 -38.750 1.00 75.37 ? 151 THR I N 1 ATOM 6134 C CA . THR D 2 168 ? 83.951 14.028 -38.880 1.00 74.44 ? 151 THR I CA 1 ATOM 6135 C C . THR D 2 168 ? 84.625 14.136 -40.237 1.00 76.28 ? 151 THR I C 1 ATOM 6136 O O . THR D 2 168 ? 84.010 13.834 -41.256 1.00 76.98 ? 151 THR I O 1 ATOM 6137 C CB . THR D 2 168 ? 83.096 12.751 -38.846 1.00 72.48 ? 151 THR I CB 1 ATOM 6138 O OG1 . THR D 2 168 ? 82.496 12.609 -37.553 1.00 70.14 ? 151 THR I OG1 1 ATOM 6139 C CG2 . THR D 2 168 ? 83.948 11.532 -39.146 1.00 72.38 ? 151 THR I CG2 1 ATOM 6140 N N . PHE D 2 169 ? 85.880 14.578 -40.253 1.00 77.89 ? 152 PHE I N 1 ATOM 6141 C CA . PHE D 2 169 ? 86.613 14.735 -41.509 1.00 80.12 ? 152 PHE I CA 1 ATOM 6142 C C . PHE D 2 169 ? 87.045 13.424 -42.175 1.00 81.73 ? 152 PHE I C 1 ATOM 6143 O O . PHE D 2 169 ? 86.916 12.342 -41.604 1.00 81.89 ? 152 PHE I O 1 ATOM 6144 C CB . PHE D 2 169 ? 87.844 15.620 -41.302 1.00 79.95 ? 152 PHE I CB 1 ATOM 6145 C CG . PHE D 2 169 ? 87.520 17.059 -41.007 1.00 81.17 ? 152 PHE I CG 1 ATOM 6146 C CD1 . PHE D 2 169 ? 86.952 17.426 -39.792 1.00 81.69 ? 152 PHE I CD1 1 ATOM 6147 C CD2 . PHE D 2 169 ? 87.793 18.054 -41.943 1.00 81.61 ? 152 PHE I CD2 1 ATOM 6148 C CE1 . PHE D 2 169 ? 86.666 18.761 -39.513 1.00 81.64 ? 152 PHE I CE1 1 ATOM 6149 C CE2 . PHE D 2 169 ? 87.510 19.391 -41.674 1.00 81.40 ? 152 PHE I CE2 1 ATOM 6150 C CZ . PHE D 2 169 ? 86.947 19.744 -40.458 1.00 81.84 ? 152 PHE I CZ 1 ATOM 6151 N N . SER D 2 170 ? 87.557 13.545 -43.396 1.00 83.61 ? 153 SER I N 1 ATOM 6152 C CA . SER D 2 170 ? 88.019 12.409 -44.189 1.00 84.87 ? 153 SER I CA 1 ATOM 6153 C C . SER D 2 170 ? 88.546 12.939 -45.506 1.00 85.59 ? 153 SER I C 1 ATOM 6154 O O . SER D 2 170 ? 88.155 14.019 -45.945 1.00 85.97 ? 153 SER I O 1 ATOM 6155 C CB . SER D 2 170 ? 86.870 11.442 -44.474 1.00 85.66 ? 153 SER I CB 1 ATOM 6156 O OG . SER D 2 170 ? 87.163 10.621 -45.597 1.00 87.00 ? 153 SER I OG 1 ATOM 6157 N N . TRP D 2 171 ? 89.422 12.182 -46.151 1.00 86.97 ? 154 TRP I N 1 ATOM 6158 C CA . TRP D 2 171 ? 89.967 12.632 -47.422 1.00 88.59 ? 154 TRP I CA 1 ATOM 6159 C C . TRP D 2 171 ? 89.914 11.616 -48.550 1.00 90.69 ? 154 TRP I C 1 ATOM 6160 O O . TRP D 2 171 ? 90.004 10.406 -48.321 1.00 91.83 ? 154 TRP I O 1 ATOM 6161 C CB . TRP D 2 171 ? 91.398 13.110 -47.223 1.00 87.01 ? 154 TRP I CB 1 ATOM 6162 C CG . TRP D 2 171 ? 91.452 14.280 -46.342 1.00 84.36 ? 154 TRP I CG 1 ATOM 6163 C CD1 . TRP D 2 171 ? 91.413 14.284 -44.985 1.00 83.64 ? 154 TRP I CD1 1 ATOM 6164 C CD2 . TRP D 2 171 ? 91.484 15.644 -46.752 1.00 83.23 ? 154 TRP I CD2 1 ATOM 6165 N NE1 . TRP D 2 171 ? 91.419 15.572 -44.518 1.00 83.07 ? 154 TRP I NE1 1 ATOM 6166 C CE2 . TRP D 2 171 ? 91.463 16.429 -45.586 1.00 83.20 ? 154 TRP I CE2 1 ATOM 6167 C CE3 . TRP D 2 171 ? 91.528 16.281 -47.995 1.00 83.38 ? 154 TRP I CE3 1 ATOM 6168 C CZ2 . TRP D 2 171 ? 91.487 17.823 -45.623 1.00 83.65 ? 154 TRP I CZ2 1 ATOM 6169 C CZ3 . TRP D 2 171 ? 91.552 17.667 -48.035 1.00 83.80 ? 154 TRP I CZ3 1 ATOM 6170 C CH2 . TRP D 2 171 ? 91.532 18.423 -46.855 1.00 83.43 ? 154 TRP I CH2 1 ATOM 6171 N N . LYS D 2 172 ? 89.757 12.128 -49.769 1.00 92.34 ? 155 LYS I N 1 ATOM 6172 C CA . LYS D 2 172 ? 89.694 11.301 -50.970 1.00 94.31 ? 155 LYS I CA 1 ATOM 6173 C C . LYS D 2 172 ? 90.544 11.954 -52.054 1.00 95.41 ? 155 LYS I C 1 ATOM 6174 O O . LYS D 2 172 ? 90.437 13.159 -52.280 1.00 96.07 ? 155 LYS I O 1 ATOM 6175 C CB . LYS D 2 172 ? 88.247 11.181 -51.462 1.00 94.68 ? 155 LYS I CB 1 ATOM 6176 C CG . LYS D 2 172 ? 87.294 10.457 -50.511 1.00 95.55 ? 155 LYS I CG 1 ATOM 6177 C CD . LYS D 2 172 ? 87.611 8.971 -50.397 1.00 95.92 ? 155 LYS I CD 1 ATOM 6178 C CE . LYS D 2 172 ? 86.614 8.261 -49.489 1.00 96.38 ? 155 LYS I CE 1 ATOM 6179 N NZ . LYS D 2 172 ? 85.212 8.370 -49.989 1.00 95.86 ? 155 LYS I NZ 1 ATOM 6180 N N . TYR D 2 173 ? 91.389 11.165 -52.715 1.00 96.32 ? 156 TYR I N 1 ATOM 6181 C CA . TYR D 2 173 ? 92.245 11.687 -53.779 1.00 97.80 ? 156 TYR I CA 1 ATOM 6182 C C . TYR D 2 173 ? 91.425 12.097 -54.997 1.00 98.98 ? 156 TYR I C 1 ATOM 6183 O O . TYR D 2 173 ? 90.213 12.306 -54.907 1.00 99.36 ? 156 TYR I O 1 ATOM 6184 C CB . TYR D 2 173 ? 93.276 10.642 -54.218 1.00 97.29 ? 156 TYR I CB 1 ATOM 6185 C CG . TYR D 2 173 ? 94.434 10.464 -53.271 1.00 97.36 ? 156 TYR I CG 1 ATOM 6186 C CD1 . TYR D 2 173 ? 94.403 9.493 -52.273 1.00 97.39 ? 156 TYR I CD1 1 ATOM 6187 C CD2 . TYR D 2 173 ? 95.559 11.278 -53.364 1.00 97.71 ? 156 TYR I CD2 1 ATOM 6188 C CE1 . TYR D 2 173 ? 95.466 9.335 -51.389 1.00 97.40 ? 156 TYR I CE1 1 ATOM 6189 C CE2 . TYR D 2 173 ? 96.626 11.133 -52.484 1.00 98.13 ? 156 TYR I CE2 1 ATOM 6190 C CZ . TYR D 2 173 ? 96.574 10.160 -51.498 1.00 97.78 ? 156 TYR I CZ 1 ATOM 6191 O OH . TYR D 2 173 ? 97.625 10.021 -50.619 1.00 98.04 ? 156 TYR I OH 1 ATOM 6192 N N . LYS D 2 174 ? 92.099 12.220 -56.138 1.00 99.67 ? 157 LYS I N 1 ATOM 6193 C CA . LYS D 2 174 ? 91.429 12.574 -57.380 1.00 100.09 ? 157 LYS I CA 1 ATOM 6194 C C . LYS D 2 174 ? 90.688 11.331 -57.862 1.00 100.69 ? 157 LYS I C 1 ATOM 6195 O O . LYS D 2 174 ? 89.852 11.402 -58.761 1.00 101.19 ? 157 LYS I O 1 ATOM 6196 C CB . LYS D 2 174 ? 92.450 13.010 -58.434 1.00 100.04 ? 157 LYS I CB 1 ATOM 6197 C CG . LYS D 2 174 ? 91.836 13.366 -59.782 1.00 99.91 ? 157 LYS I CG 1 ATOM 6198 C CD . LYS D 2 174 ? 92.900 13.760 -60.795 1.00 99.84 ? 157 LYS I CD 1 ATOM 6199 C CE . LYS D 2 174 ? 92.288 14.105 -62.148 1.00 99.16 ? 157 LYS I CE 1 ATOM 6200 N NZ . LYS D 2 174 ? 91.563 12.952 -62.740 1.00 98.96 ? 157 LYS I NZ 1 ATOM 6201 N N . ASN D 2 175 ? 91.000 10.195 -57.242 1.00 101.22 ? 158 ASN I N 1 ATOM 6202 C CA . ASN D 2 175 ? 90.391 8.919 -57.596 1.00 101.70 ? 158 ASN I CA 1 ATOM 6203 C C . ASN D 2 175 ? 89.793 8.177 -56.402 1.00 102.62 ? 158 ASN I C 1 ATOM 6204 O O . ASN D 2 175 ? 90.243 7.088 -56.058 1.00 103.00 ? 158 ASN I O 1 ATOM 6205 C CB . ASN D 2 175 ? 91.428 8.028 -58.288 1.00 101.37 ? 158 ASN I CB 1 ATOM 6206 C CG . ASN D 2 175 ? 92.761 7.994 -57.549 1.00 102.11 ? 158 ASN I CG 1 ATOM 6207 O OD1 . ASN D 2 175 ? 93.441 9.015 -57.416 1.00 102.31 ? 158 ASN I OD1 1 ATOM 6208 N ND2 . ASN D 2 175 ? 93.140 6.817 -57.067 1.00 101.75 ? 158 ASN I ND2 1 ATOM 6209 N N . ASN D 2 176 ? 88.774 8.771 -55.786 1.00 103.79 ? 159 ASN I N 1 ATOM 6210 C CA . ASN D 2 176 ? 88.078 8.190 -54.633 1.00 104.52 ? 159 ASN I CA 1 ATOM 6211 C C . ASN D 2 176 ? 88.932 7.274 -53.752 1.00 104.72 ? 159 ASN I C 1 ATOM 6212 O O . ASN D 2 176 ? 88.473 6.222 -53.300 1.00 103.58 ? 159 ASN I O 1 ATOM 6213 C CB . ASN D 2 176 ? 86.826 7.434 -55.103 1.00 104.34 ? 159 ASN I CB 1 ATOM 6214 C CG . ASN D 2 176 ? 85.980 6.916 -53.947 1.00 104.39 ? 159 ASN I CG 1 ATOM 6215 O OD1 . ASN D 2 176 ? 85.539 7.684 -53.090 1.00 104.41 ? 159 ASN I OD1 1 ATOM 6216 N ND2 . ASN D 2 176 ? 85.749 5.608 -53.921 1.00 104.82 ? 159 ASN I ND2 1 ATOM 6217 N N . SER D 2 177 ? 90.173 7.684 -53.510 1.00 105.79 ? 160 SER I N 1 ATOM 6218 C CA . SER D 2 177 ? 91.087 6.913 -52.670 1.00 107.12 ? 160 SER I CA 1 ATOM 6219 C C . SER D 2 177 ? 91.067 7.506 -51.267 1.00 108.42 ? 160 SER I C 1 ATOM 6220 O O . SER D 2 177 ? 90.840 8.703 -51.105 1.00 109.04 ? 160 SER I O 1 ATOM 6221 C CB . SER D 2 177 ? 92.512 6.981 -53.225 1.00 106.29 ? 160 SER I CB 1 ATOM 6222 O OG . SER D 2 177 ? 92.586 6.448 -54.534 1.00 105.90 ? 160 SER I OG 1 ATOM 6223 N N . ASP D 2 178 ? 91.298 6.675 -50.255 1.00 109.40 ? 161 ASP I N 1 ATOM 6224 C CA . ASP D 2 178 ? 91.309 7.154 -48.875 1.00 110.08 ? 161 ASP I CA 1 ATOM 6225 C C . ASP D 2 178 ? 92.680 7.749 -48.557 1.00 109.59 ? 161 ASP I C 1 ATOM 6226 O O . ASP D 2 178 ? 93.660 7.459 -49.243 1.00 109.80 ? 161 ASP I O 1 ATOM 6227 C CB . ASP D 2 178 ? 90.994 6.002 -47.917 1.00 111.52 ? 161 ASP I CB 1 ATOM 6228 C CG . ASP D 2 178 ? 89.662 5.336 -48.226 1.00 114.08 ? 161 ASP I CG 1 ATOM 6229 O OD1 . ASP D 2 178 ? 88.624 6.033 -48.191 1.00 115.56 ? 161 ASP I OD1 1 ATOM 6230 O OD2 . ASP D 2 178 ? 89.650 4.117 -48.506 1.00 115.47 ? 161 ASP I OD2 1 ATOM 6231 N N . ILE D 2 179 ? 92.750 8.593 -47.532 1.00 108.80 ? 162 ILE I N 1 ATOM 6232 C CA . ILE D 2 179 ? 94.020 9.206 -47.146 1.00 108.36 ? 162 ILE I CA 1 ATOM 6233 C C . ILE D 2 179 ? 94.309 8.999 -45.649 1.00 108.97 ? 162 ILE I C 1 ATOM 6234 O O . ILE D 2 179 ? 93.452 9.258 -44.796 1.00 108.84 ? 162 ILE I O 1 ATOM 6235 C CB . ILE D 2 179 ? 94.037 10.723 -47.478 1.00 106.90 ? 162 ILE I CB 1 ATOM 6236 C CG1 . ILE D 2 179 ? 93.858 10.932 -48.985 1.00 104.70 ? 162 ILE I CG1 1 ATOM 6237 C CG2 . ILE D 2 179 ? 95.349 11.341 -47.023 1.00 107.20 ? 162 ILE I CG2 1 ATOM 6238 C CD1 . ILE D 2 179 ? 93.944 12.380 -49.432 1.00 101.97 ? 162 ILE I CD1 1 ATOM 6239 N N . SER D 2 180 ? 95.516 8.523 -45.341 1.00 109.04 ? 163 SER I N 1 ATOM 6240 C CA . SER D 2 180 ? 95.921 8.266 -43.959 1.00 108.59 ? 163 SER I CA 1 ATOM 6241 C C . SER D 2 180 ? 96.650 9.448 -43.332 1.00 108.06 ? 163 SER I C 1 ATOM 6242 O O . SER D 2 180 ? 96.779 9.531 -42.108 1.00 107.43 ? 163 SER I O 1 ATOM 6243 C CB . SER D 2 180 ? 96.804 7.016 -43.889 1.00 108.32 ? 163 SER I CB 1 ATOM 6244 O OG . SER D 2 180 ? 96.061 5.844 -44.187 1.00 107.40 ? 163 SER I OG 1 ATOM 6245 N N . SER D 2 181 ? 97.129 10.357 -44.174 1.00 107.67 ? 164 SER I N 1 ATOM 6246 C CA . SER D 2 181 ? 97.827 11.543 -43.698 1.00 108.04 ? 164 SER I CA 1 ATOM 6247 C C . SER D 2 181 ? 96.782 12.522 -43.174 1.00 108.06 ? 164 SER I C 1 ATOM 6248 O O . SER D 2 181 ? 96.686 13.660 -43.637 1.00 108.36 ? 164 SER I O 1 ATOM 6249 C CB . SER D 2 181 ? 98.612 12.185 -44.838 1.00 108.24 ? 164 SER I CB 1 ATOM 6250 O OG . SER D 2 181 ? 99.278 13.350 -44.386 1.00 109.68 ? 164 SER I OG 1 ATOM 6251 N N . THR D 2 182 ? 96.009 12.068 -42.194 1.00 107.81 ? 165 THR I N 1 ATOM 6252 C CA . THR D 2 182 ? 94.939 12.871 -41.621 1.00 106.75 ? 165 THR I CA 1 ATOM 6253 C C . THR D 2 182 ? 95.136 13.256 -40.158 1.00 106.60 ? 165 THR I C 1 ATOM 6254 O O . THR D 2 182 ? 95.448 12.413 -39.315 1.00 106.54 ? 165 THR I O 1 ATOM 6255 C CB . THR D 2 182 ? 93.598 12.124 -41.748 1.00 106.39 ? 165 THR I CB 1 ATOM 6256 O OG1 . THR D 2 182 ? 93.723 10.817 -41.167 1.00 105.33 ? 165 THR I OG1 1 ATOM 6257 C CG2 . THR D 2 182 ? 93.203 11.987 -43.212 1.00 106.01 ? 165 THR I CG2 1 ATOM 6258 N N . ARG D 2 183 ? 94.944 14.538 -39.864 1.00 106.30 ? 166 ARG I N 1 ATOM 6259 C CA . ARG D 2 183 ? 95.070 15.042 -38.501 1.00 105.56 ? 166 ARG I CA 1 ATOM 6260 C C . ARG D 2 183 ? 93.871 15.910 -38.164 1.00 104.06 ? 166 ARG I C 1 ATOM 6261 O O . ARG D 2 183 ? 93.691 16.990 -38.730 1.00 103.13 ? 166 ARG I O 1 ATOM 6262 C CB . ARG D 2 183 ? 96.353 15.854 -38.336 1.00 106.67 ? 166 ARG I CB 1 ATOM 6263 C CG . ARG D 2 183 ? 97.607 15.029 -38.489 1.00 108.02 ? 166 ARG I CG 1 ATOM 6264 C CD . ARG D 2 183 ? 98.839 15.893 -38.414 1.00 109.12 ? 166 ARG I CD 1 ATOM 6265 N NE . ARG D 2 183 ? 100.042 15.125 -38.707 1.00 111.05 ? 166 ARG I NE 1 ATOM 6266 C CZ . ARG D 2 183 ? 101.260 15.651 -38.772 1.00 112.77 ? 166 ARG I CZ 1 ATOM 6267 N NH1 . ARG D 2 183 ? 101.434 16.950 -38.563 1.00 113.75 ? 166 ARG I NH1 1 ATOM 6268 N NH2 . ARG D 2 183 ? 102.303 14.880 -39.050 1.00 113.52 ? 166 ARG I NH2 1 ATOM 6269 N N . GLY D 2 184 ? 93.052 15.416 -37.241 1.00 102.58 ? 167 GLY I N 1 ATOM 6270 C CA . GLY D 2 184 ? 91.867 16.142 -36.825 1.00 100.11 ? 167 GLY I CA 1 ATOM 6271 C C . GLY D 2 184 ? 92.146 17.081 -35.671 1.00 97.68 ? 167 GLY I C 1 ATOM 6272 O O . GLY D 2 184 ? 92.864 16.737 -34.733 1.00 97.77 ? 167 GLY I O 1 ATOM 6273 N N . PHE D 2 185 ? 91.567 18.272 -35.741 1.00 95.59 ? 168 PHE I N 1 ATOM 6274 C CA . PHE D 2 185 ? 91.753 19.281 -34.709 1.00 93.11 ? 168 PHE I CA 1 ATOM 6275 C C . PHE D 2 185 ? 90.449 19.572 -33.970 1.00 91.48 ? 168 PHE I C 1 ATOM 6276 O O . PHE D 2 185 ? 89.361 19.242 -34.447 1.00 91.78 ? 168 PHE I O 1 ATOM 6277 C CB . PHE D 2 185 ? 92.297 20.566 -35.343 1.00 92.66 ? 168 PHE I CB 1 ATOM 6278 C CG . PHE D 2 185 ? 93.673 20.414 -35.932 1.00 92.72 ? 168 PHE I CG 1 ATOM 6279 C CD1 . PHE D 2 185 ? 93.945 19.412 -36.857 1.00 92.71 ? 168 PHE I CD1 1 ATOM 6280 C CD2 . PHE D 2 185 ? 94.704 21.265 -35.550 1.00 92.38 ? 168 PHE I CD2 1 ATOM 6281 C CE1 . PHE D 2 185 ? 95.223 19.260 -37.388 1.00 92.79 ? 168 PHE I CE1 1 ATOM 6282 C CE2 . PHE D 2 185 ? 95.984 21.120 -36.076 1.00 91.43 ? 168 PHE I CE2 1 ATOM 6283 C CZ . PHE D 2 185 ? 96.243 20.117 -36.995 1.00 91.52 ? 168 PHE I CZ 1 ATOM 6284 N N . PRO D 2 186 ? 90.544 20.183 -32.781 1.00 89.66 ? 169 PRO I N 1 ATOM 6285 C CA . PRO D 2 186 ? 89.363 20.517 -31.987 1.00 87.33 ? 169 PRO I CA 1 ATOM 6286 C C . PRO D 2 186 ? 88.669 21.723 -32.594 1.00 85.30 ? 169 PRO I C 1 ATOM 6287 O O . PRO D 2 186 ? 89.310 22.560 -33.223 1.00 84.29 ? 169 PRO I O 1 ATOM 6288 C CB . PRO D 2 186 ? 89.950 20.817 -30.617 1.00 88.35 ? 169 PRO I CB 1 ATOM 6289 C CG . PRO D 2 186 ? 91.245 21.466 -30.967 1.00 89.80 ? 169 PRO I CG 1 ATOM 6290 C CD . PRO D 2 186 ? 91.773 20.554 -32.059 1.00 90.34 ? 169 PRO I CD 1 ATOM 6291 N N . SER D 2 187 ? 87.359 21.808 -32.399 1.00 84.42 ? 170 SER I N 1 ATOM 6292 C CA . SER D 2 187 ? 86.576 22.907 -32.945 1.00 83.16 ? 170 SER I CA 1 ATOM 6293 C C . SER D 2 187 ? 86.680 24.186 -32.126 1.00 83.20 ? 170 SER I C 1 ATOM 6294 O O . SER D 2 187 ? 86.989 24.163 -30.935 1.00 82.73 ? 170 SER I O 1 ATOM 6295 C CB . SER D 2 187 ? 85.108 22.493 -33.059 1.00 81.82 ? 170 SER I CB 1 ATOM 6296 O OG . SER D 2 187 ? 84.967 21.337 -33.864 1.00 79.74 ? 170 SER I OG 1 ATOM 6297 N N . VAL D 2 188 ? 86.422 25.306 -32.786 1.00 83.69 ? 171 VAL I N 1 ATOM 6298 C CA . VAL D 2 188 ? 86.459 26.606 -32.144 1.00 84.89 ? 171 VAL I CA 1 ATOM 6299 C C . VAL D 2 188 ? 85.028 27.153 -32.117 1.00 86.16 ? 171 VAL I C 1 ATOM 6300 O O . VAL D 2 188 ? 84.307 27.080 -33.117 1.00 86.43 ? 171 VAL I O 1 ATOM 6301 C CB . VAL D 2 188 ? 87.368 27.579 -32.922 1.00 84.83 ? 171 VAL I CB 1 ATOM 6302 C CG1 . VAL D 2 188 ? 86.791 27.844 -34.307 1.00 85.57 ? 171 VAL I CG1 1 ATOM 6303 C CG2 . VAL D 2 188 ? 87.515 28.875 -32.157 1.00 84.74 ? 171 VAL I CG2 1 ATOM 6304 N N . LEU D 2 189 ? 84.617 27.689 -30.971 1.00 86.95 ? 172 LEU I N 1 ATOM 6305 C CA . LEU D 2 189 ? 83.271 28.231 -30.829 1.00 87.83 ? 172 LEU I CA 1 ATOM 6306 C C . LEU D 2 189 ? 83.296 29.739 -31.022 1.00 88.36 ? 172 LEU I C 1 ATOM 6307 O O . LEU D 2 189 ? 83.656 30.477 -30.109 1.00 88.65 ? 172 LEU I O 1 ATOM 6308 C CB . LEU D 2 189 ? 82.713 27.897 -29.442 1.00 88.31 ? 172 LEU I CB 1 ATOM 6309 C CG . LEU D 2 189 ? 81.197 27.992 -29.217 1.00 89.02 ? 172 LEU I CG 1 ATOM 6310 C CD1 . LEU D 2 189 ? 80.886 27.582 -27.787 1.00 88.70 ? 172 LEU I CD1 1 ATOM 6311 C CD2 . LEU D 2 189 ? 80.696 29.399 -29.490 1.00 89.69 ? 172 LEU I CD2 1 ATOM 6312 N N . ARG D 2 190 ? 82.911 30.191 -32.212 1.00 89.48 ? 173 ARG I N 1 ATOM 6313 C CA . ARG D 2 190 ? 82.890 31.617 -32.526 1.00 89.65 ? 173 ARG I CA 1 ATOM 6314 C C . ARG D 2 190 ? 81.456 32.102 -32.606 1.00 88.21 ? 173 ARG I C 1 ATOM 6315 O O . ARG D 2 190 ? 80.682 31.615 -33.425 1.00 88.96 ? 173 ARG I O 1 ATOM 6316 C CB . ARG D 2 190 ? 83.572 31.886 -33.870 1.00 91.80 ? 173 ARG I CB 1 ATOM 6317 C CG . ARG D 2 190 ? 83.764 33.371 -34.189 1.00 94.46 ? 173 ARG I CG 1 ATOM 6318 C CD . ARG D 2 190 ? 83.809 33.660 -35.697 1.00 96.93 ? 173 ARG I CD 1 ATOM 6319 N NE . ARG D 2 190 ? 84.759 32.826 -36.437 1.00 99.26 ? 173 ARG I NE 1 ATOM 6320 C CZ . ARG D 2 190 ? 84.532 31.569 -36.821 1.00 100.27 ? 173 ARG I CZ 1 ATOM 6321 N NH1 . ARG D 2 190 ? 83.375 30.974 -36.542 1.00 99.74 ? 173 ARG I NH1 1 ATOM 6322 N NH2 . ARG D 2 190 ? 85.468 30.904 -37.492 1.00 100.31 ? 173 ARG I NH2 1 ATOM 6323 N N . GLY D 2 191 ? 81.110 33.059 -31.753 1.00 86.39 ? 174 GLY I N 1 ATOM 6324 C CA . GLY D 2 191 ? 79.767 33.615 -31.747 1.00 84.77 ? 174 GLY I CA 1 ATOM 6325 C C . GLY D 2 191 ? 78.615 32.695 -32.128 1.00 83.23 ? 174 GLY I C 1 ATOM 6326 O O . GLY D 2 191 ? 78.008 32.856 -33.191 1.00 82.82 ? 174 GLY I O 1 ATOM 6327 N N . GLY D 2 192 ? 78.320 31.728 -31.263 1.00 81.50 ? 175 GLY I N 1 ATOM 6328 C CA . GLY D 2 192 ? 77.219 30.811 -31.504 1.00 79.96 ? 175 GLY I CA 1 ATOM 6329 C C . GLY D 2 192 ? 77.414 29.661 -32.477 1.00 79.35 ? 175 GLY I C 1 ATOM 6330 O O . GLY D 2 192 ? 76.614 28.729 -32.489 1.00 78.80 ? 175 GLY I O 1 ATOM 6331 N N . LYS D 2 193 ? 78.458 29.712 -33.297 1.00 79.17 ? 176 LYS I N 1 ATOM 6332 C CA . LYS D 2 193 ? 78.709 28.646 -34.264 1.00 78.52 ? 176 LYS I CA 1 ATOM 6333 C C . LYS D 2 193 ? 80.118 28.092 -34.086 1.00 79.66 ? 176 LYS I C 1 ATOM 6334 O O . LYS D 2 193 ? 80.999 28.788 -33.576 1.00 80.30 ? 176 LYS I O 1 ATOM 6335 C CB . LYS D 2 193 ? 78.548 29.183 -35.682 1.00 77.27 ? 176 LYS I CB 1 ATOM 6336 C CG . LYS D 2 193 ? 77.164 29.716 -36.015 1.00 75.83 ? 176 LYS I CG 1 ATOM 6337 C CD . LYS D 2 193 ? 76.233 28.610 -36.441 1.00 74.03 ? 176 LYS I CD 1 ATOM 6338 C CE . LYS D 2 193 ? 75.048 29.174 -37.198 1.00 74.56 ? 176 LYS I CE 1 ATOM 6339 N NZ . LYS D 2 193 ? 74.306 28.112 -37.942 1.00 74.50 ? 176 LYS I NZ 1 ATOM 6340 N N . TYR D 2 194 ? 80.324 26.843 -34.507 1.00 79.98 ? 177 TYR I N 1 ATOM 6341 C CA . TYR D 2 194 ? 81.627 26.188 -34.395 1.00 79.44 ? 177 TYR I CA 1 ATOM 6342 C C . TYR D 2 194 ? 82.395 26.181 -35.713 1.00 78.55 ? 177 TYR I C 1 ATOM 6343 O O . TYR D 2 194 ? 81.845 26.489 -36.768 1.00 76.98 ? 177 TYR I O 1 ATOM 6344 C CB . TYR D 2 194 ? 81.461 24.748 -33.917 1.00 80.78 ? 177 TYR I CB 1 ATOM 6345 C CG . TYR D 2 194 ? 81.023 24.601 -32.475 1.00 83.35 ? 177 TYR I CG 1 ATOM 6346 C CD1 . TYR D 2 194 ? 81.818 25.067 -31.427 1.00 83.84 ? 177 TYR I CD1 1 ATOM 6347 C CD2 . TYR D 2 194 ? 79.836 23.942 -32.153 1.00 83.91 ? 177 TYR I CD2 1 ATOM 6348 C CE1 . TYR D 2 194 ? 81.439 24.871 -30.088 1.00 84.15 ? 177 TYR I CE1 1 ATOM 6349 C CE2 . TYR D 2 194 ? 79.449 23.743 -30.822 1.00 83.71 ? 177 TYR I CE2 1 ATOM 6350 C CZ . TYR D 2 194 ? 80.252 24.207 -29.796 1.00 83.90 ? 177 TYR I CZ 1 ATOM 6351 O OH . TYR D 2 194 ? 79.870 24.003 -28.487 1.00 83.28 ? 177 TYR I OH 1 ATOM 6352 N N . ALA D 2 195 ? 83.670 25.816 -35.631 1.00 78.54 ? 178 ALA I N 1 ATOM 6353 C CA . ALA D 2 195 ? 84.556 25.753 -36.790 1.00 78.65 ? 178 ALA I CA 1 ATOM 6354 C C . ALA D 2 195 ? 85.682 24.762 -36.497 1.00 78.36 ? 178 ALA I C 1 ATOM 6355 O O . ALA D 2 195 ? 86.220 24.741 -35.395 1.00 77.59 ? 178 ALA I O 1 ATOM 6356 C CB . ALA D 2 195 ? 85.132 27.136 -37.082 1.00 78.52 ? 178 ALA I CB 1 ATOM 6357 N N . ALA D 2 196 ? 86.033 23.939 -37.480 1.00 78.69 ? 179 ALA I N 1 ATOM 6358 C CA . ALA D 2 196 ? 87.091 22.950 -37.296 1.00 80.25 ? 179 ALA I CA 1 ATOM 6359 C C . ALA D 2 196 ? 87.872 22.717 -38.582 1.00 81.80 ? 179 ALA I C 1 ATOM 6360 O O . ALA D 2 196 ? 87.356 22.923 -39.675 1.00 82.85 ? 179 ALA I O 1 ATOM 6361 C CB . ALA D 2 196 ? 86.499 21.638 -36.806 1.00 79.53 ? 179 ALA I CB 1 ATOM 6362 N N . THR D 2 197 ? 89.117 22.275 -38.448 1.00 83.64 ? 180 THR I N 1 ATOM 6363 C CA . THR D 2 197 ? 89.965 22.034 -39.608 1.00 84.62 ? 180 THR I CA 1 ATOM 6364 C C . THR D 2 197 ? 90.694 20.703 -39.514 1.00 86.64 ? 180 THR I C 1 ATOM 6365 O O . THR D 2 197 ? 90.940 20.196 -38.419 1.00 87.26 ? 180 THR I O 1 ATOM 6366 C CB . THR D 2 197 ? 91.030 23.134 -39.747 1.00 83.56 ? 180 THR I CB 1 ATOM 6367 O OG1 . THR D 2 197 ? 90.399 24.418 -39.734 1.00 82.77 ? 180 THR I OG1 1 ATOM 6368 C CG2 . THR D 2 197 ? 91.797 22.969 -41.045 1.00 83.28 ? 180 THR I CG2 1 ATOM 6369 N N . SER D 2 198 ? 91.031 20.139 -40.670 1.00 88.47 ? 181 SER I N 1 ATOM 6370 C CA . SER D 2 198 ? 91.775 18.886 -40.729 1.00 91.18 ? 181 SER I CA 1 ATOM 6371 C C . SER D 2 198 ? 92.918 19.148 -41.692 1.00 93.53 ? 181 SER I C 1 ATOM 6372 O O . SER D 2 198 ? 92.854 20.091 -42.487 1.00 93.36 ? 181 SER I O 1 ATOM 6373 C CB . SER D 2 198 ? 90.917 17.764 -41.277 1.00 90.61 ? 181 SER I CB 1 ATOM 6374 O OG . SER D 2 198 ? 90.733 17.950 -42.662 1.00 92.18 ? 181 SER I OG 1 ATOM 6375 N N . GLN D 2 199 ? 93.958 18.321 -41.634 1.00 96.63 ? 182 GLN I N 1 ATOM 6376 C CA . GLN D 2 199 ? 95.110 18.515 -42.509 1.00 99.26 ? 182 GLN I CA 1 ATOM 6377 C C . GLN D 2 199 ? 95.663 17.226 -43.108 1.00 101.15 ? 182 GLN I C 1 ATOM 6378 O O . GLN D 2 199 ? 95.517 16.141 -42.536 1.00 100.82 ? 182 GLN I O 1 ATOM 6379 C CB . GLN D 2 199 ? 96.217 19.239 -41.745 1.00 98.92 ? 182 GLN I CB 1 ATOM 6380 C CG . GLN D 2 199 ? 97.441 19.554 -42.571 1.00 98.78 ? 182 GLN I CG 1 ATOM 6381 C CD . GLN D 2 199 ? 98.576 20.076 -41.725 1.00 98.41 ? 182 GLN I CD 1 ATOM 6382 O OE1 . GLN D 2 199 ? 99.016 19.413 -40.787 1.00 98.11 ? 182 GLN I OE1 1 ATOM 6383 N NE2 . GLN D 2 199 ? 99.060 21.269 -42.049 1.00 98.23 ? 182 GLN I NE2 1 ATOM 6384 N N . VAL D 2 200 ? 96.302 17.363 -44.267 1.00 103.73 ? 183 VAL I N 1 ATOM 6385 C CA . VAL D 2 200 ? 96.888 16.229 -44.968 1.00 106.66 ? 183 VAL I CA 1 ATOM 6386 C C . VAL D 2 200 ? 98.275 16.569 -45.512 1.00 108.71 ? 183 VAL I C 1 ATOM 6387 O O . VAL D 2 200 ? 98.501 17.666 -46.020 1.00 108.35 ? 183 VAL I O 1 ATOM 6388 C CB . VAL D 2 200 ? 95.988 15.782 -46.133 1.00 106.43 ? 183 VAL I CB 1 ATOM 6389 C CG1 . VAL D 2 200 ? 96.589 14.572 -46.823 1.00 106.89 ? 183 VAL I CG1 1 ATOM 6390 C CG2 . VAL D 2 200 ? 94.606 15.455 -45.616 1.00 106.56 ? 183 VAL I CG2 1 ATOM 6391 N N . LEU D 2 201 ? 99.195 15.614 -45.402 1.00 111.76 ? 184 LEU I N 1 ATOM 6392 C CA . LEU D 2 201 ? 100.575 15.777 -45.864 1.00 114.95 ? 184 LEU I CA 1 ATOM 6393 C C . LEU D 2 201 ? 100.811 14.951 -47.132 1.00 117.06 ? 184 LEU I C 1 ATOM 6394 O O . LEU D 2 201 ? 100.294 13.838 -47.256 1.00 117.60 ? 184 LEU I O 1 ATOM 6395 C CB . LEU D 2 201 ? 101.543 15.310 -44.770 1.00 115.08 ? 184 LEU I CB 1 ATOM 6396 C CG . LEU D 2 201 ? 101.266 15.766 -43.332 1.00 115.22 ? 184 LEU I CG 1 ATOM 6397 C CD1 . LEU D 2 201 ? 102.188 15.021 -42.384 1.00 114.55 ? 184 LEU I CD1 1 ATOM 6398 C CD2 . LEU D 2 201 ? 101.456 17.277 -43.206 1.00 115.15 ? 184 LEU I CD2 1 ATOM 6399 N N . LEU D 2 202 ? 101.595 15.482 -48.066 1.00 119.23 ? 185 LEU I N 1 ATOM 6400 C CA . LEU D 2 202 ? 101.867 14.763 -49.308 1.00 121.70 ? 185 LEU I CA 1 ATOM 6401 C C . LEU D 2 202 ? 103.265 15.014 -49.876 1.00 123.68 ? 185 LEU I C 1 ATOM 6402 O O . LEU D 2 202 ? 103.665 16.161 -50.069 1.00 123.65 ? 185 LEU I O 1 ATOM 6403 C CB . LEU D 2 202 ? 100.809 15.119 -50.355 1.00 121.13 ? 185 LEU I CB 1 ATOM 6404 C CG . LEU D 2 202 ? 99.386 14.653 -50.023 1.00 121.78 ? 185 LEU I CG 1 ATOM 6405 C CD1 . LEU D 2 202 ? 98.425 15.129 -51.102 1.00 121.38 ? 185 LEU I CD1 1 ATOM 6406 C CD2 . LEU D 2 202 ? 99.350 13.128 -49.898 1.00 121.48 ? 185 LEU I CD2 1 ATOM 6407 N N . PRO D 2 203 ? 104.021 13.930 -50.155 1.00 125.81 ? 186 PRO I N 1 ATOM 6408 C CA . PRO D 2 203 ? 105.388 13.929 -50.702 1.00 127.21 ? 186 PRO I CA 1 ATOM 6409 C C . PRO D 2 203 ? 105.639 14.797 -51.946 1.00 128.84 ? 186 PRO I C 1 ATOM 6410 O O . PRO D 2 203 ? 106.327 15.816 -51.868 1.00 128.86 ? 186 PRO I O 1 ATOM 6411 C CB . PRO D 2 203 ? 105.641 12.448 -50.969 1.00 126.73 ? 186 PRO I CB 1 ATOM 6412 C CG . PRO D 2 203 ? 104.897 11.790 -49.854 1.00 126.26 ? 186 PRO I CG 1 ATOM 6413 C CD . PRO D 2 203 ? 103.590 12.549 -49.858 1.00 125.97 ? 186 PRO I CD 1 ATOM 6414 N N . SER D 2 204 ? 105.101 14.377 -53.090 1.00 130.87 ? 187 SER I N 1 ATOM 6415 C CA . SER D 2 204 ? 105.263 15.111 -54.351 1.00 132.88 ? 187 SER I CA 1 ATOM 6416 C C . SER D 2 204 ? 104.393 14.479 -55.439 1.00 134.19 ? 187 SER I C 1 ATOM 6417 O O . SER D 2 204 ? 103.604 15.156 -56.101 1.00 133.76 ? 187 SER I O 1 ATOM 6418 C CB . SER D 2 204 ? 106.732 15.098 -54.793 1.00 132.83 ? 187 SER I CB 1 ATOM 6419 O OG . SER D 2 204 ? 107.197 13.777 -55.023 1.00 132.41 ? 187 SER I OG 1 ATOM 6420 N N . LYS D 2 205 ? 104.565 13.172 -55.607 1.00 136.01 ? 188 LYS I N 1 ATOM 6421 C CA . LYS D 2 205 ? 103.827 12.359 -56.571 1.00 138.14 ? 188 LYS I CA 1 ATOM 6422 C C . LYS D 2 205 ? 104.104 10.910 -56.171 1.00 140.39 ? 188 LYS I C 1 ATOM 6423 O O . LYS D 2 205 ? 103.913 9.983 -56.963 1.00 141.28 ? 188 LYS I O 1 ATOM 6424 C CB . LYS D 2 205 ? 104.330 12.593 -58.005 1.00 136.72 ? 188 LYS I CB 1 ATOM 6425 C CG . LYS D 2 205 ? 103.977 13.944 -58.613 1.00 134.64 ? 188 LYS I CG 1 ATOM 6426 C CD . LYS D 2 205 ? 104.429 14.032 -60.064 1.00 131.96 ? 188 LYS I CD 1 ATOM 6427 C CE . LYS D 2 205 ? 104.116 15.392 -60.659 1.00 130.15 ? 188 LYS I CE 1 ATOM 6428 N NZ . LYS D 2 205 ? 104.798 16.482 -59.914 1.00 128.99 ? 188 LYS I NZ 1 ATOM 6429 N N . ASP D 2 206 ? 104.556 10.737 -54.929 1.00 142.31 ? 189 ASP I N 1 ATOM 6430 C CA . ASP D 2 206 ? 104.909 9.428 -54.378 1.00 143.82 ? 189 ASP I CA 1 ATOM 6431 C C . ASP D 2 206 ? 103.723 8.521 -54.048 1.00 144.49 ? 189 ASP I C 1 ATOM 6432 O O . ASP D 2 206 ? 102.917 8.192 -54.921 1.00 144.99 ? 189 ASP I O 1 ATOM 6433 C CB . ASP D 2 206 ? 105.772 9.614 -53.122 1.00 144.30 ? 189 ASP I CB 1 ATOM 6434 C CG . ASP D 2 206 ? 107.063 10.374 -53.399 1.00 144.76 ? 189 ASP I CG 1 ATOM 6435 O OD1 . ASP D 2 206 ? 107.829 10.611 -52.441 1.00 145.02 ? 189 ASP I OD1 1 ATOM 6436 O OD2 . ASP D 2 206 ? 107.314 10.734 -54.569 1.00 144.73 ? 189 ASP I OD2 1 ATOM 6437 N N . VAL D 2 207 ? 103.635 8.117 -52.782 1.00 145.09 ? 190 VAL I N 1 ATOM 6438 C CA . VAL D 2 207 ? 102.575 7.236 -52.289 1.00 145.64 ? 190 VAL I CA 1 ATOM 6439 C C . VAL D 2 207 ? 102.173 6.142 -53.281 1.00 145.87 ? 190 VAL I C 1 ATOM 6440 O O . VAL D 2 207 ? 103.019 5.376 -53.748 1.00 146.01 ? 190 VAL I O 1 ATOM 6441 C CB . VAL D 2 207 ? 101.319 8.048 -51.873 1.00 145.47 ? 190 VAL I CB 1 ATOM 6442 C CG1 . VAL D 2 207 ? 101.619 8.847 -50.616 1.00 145.88 ? 190 VAL I CG1 1 ATOM 6443 C CG2 . VAL D 2 207 ? 100.896 8.984 -52.991 1.00 145.42 ? 190 VAL I CG2 1 ATOM 6444 N N . MET D 2 208 ? 100.883 6.065 -53.593 1.00 145.91 ? 191 MET I N 1 ATOM 6445 C CA . MET D 2 208 ? 100.375 5.066 -54.526 1.00 145.62 ? 191 MET I CA 1 ATOM 6446 C C . MET D 2 208 ? 99.396 5.709 -55.507 1.00 145.03 ? 191 MET I C 1 ATOM 6447 O O . MET D 2 208 ? 99.766 6.042 -56.634 1.00 144.78 ? 191 MET I O 1 ATOM 6448 C CB . MET D 2 208 ? 99.685 3.936 -53.755 1.00 146.08 ? 191 MET I CB 1 ATOM 6449 C CG . MET D 2 208 ? 100.592 3.227 -52.757 1.00 146.38 ? 191 MET I CG 1 ATOM 6450 S SD . MET D 2 208 ? 99.735 1.965 -51.791 1.00 146.84 ? 191 MET I SD 1 ATOM 6451 C CE . MET D 2 208 ? 99.365 2.869 -50.294 1.00 146.55 ? 191 MET I CE 1 ATOM 6452 N N . GLN D 2 209 ? 98.150 5.880 -55.072 1.00 144.33 ? 192 GLN I N 1 ATOM 6453 C CA . GLN D 2 209 ? 97.115 6.494 -55.901 1.00 143.65 ? 192 GLN I CA 1 ATOM 6454 C C . GLN D 2 209 ? 97.219 8.013 -55.831 1.00 143.36 ? 192 GLN I C 1 ATOM 6455 O O . GLN D 2 209 ? 96.404 8.730 -56.412 1.00 143.01 ? 192 GLN I O 1 ATOM 6456 C CB . GLN D 2 209 ? 95.724 6.061 -55.429 1.00 143.40 ? 192 GLN I CB 1 ATOM 6457 C CG . GLN D 2 209 ? 95.361 4.611 -55.722 1.00 142.68 ? 192 GLN I CG 1 ATOM 6458 C CD . GLN D 2 209 ? 95.146 4.337 -57.202 1.00 142.17 ? 192 GLN I CD 1 ATOM 6459 O OE1 . GLN D 2 209 ? 94.720 3.247 -57.586 1.00 141.52 ? 192 GLN I OE1 1 ATOM 6460 N NE2 . GLN D 2 209 ? 95.443 5.326 -58.039 1.00 141.68 ? 192 GLN I NE2 1 ATOM 6461 N N . GLY D 2 210 ? 98.228 8.493 -55.111 1.00 143.40 ? 193 GLY I N 1 ATOM 6462 C CA . GLY D 2 210 ? 98.432 9.923 -54.965 1.00 143.52 ? 193 GLY I CA 1 ATOM 6463 C C . GLY D 2 210 ? 99.002 10.573 -56.209 1.00 143.45 ? 193 GLY I C 1 ATOM 6464 O O . GLY D 2 210 ? 100.195 10.878 -56.275 1.00 143.15 ? 193 GLY I O 1 ATOM 6465 N N . THR D 2 211 ? 98.136 10.782 -57.196 1.00 143.25 ? 194 THR I N 1 ATOM 6466 C CA . THR D 2 211 ? 98.516 11.400 -58.461 1.00 142.69 ? 194 THR I CA 1 ATOM 6467 C C . THR D 2 211 ? 99.120 12.786 -58.232 1.00 141.60 ? 194 THR I C 1 ATOM 6468 O O . THR D 2 211 ? 100.027 12.950 -57.416 1.00 141.47 ? 194 THR I O 1 ATOM 6469 C CB . THR D 2 211 ? 97.284 11.521 -59.397 1.00 143.46 ? 194 THR I CB 1 ATOM 6470 O OG1 . THR D 2 211 ? 96.210 12.170 -58.702 1.00 143.45 ? 194 THR I OG1 1 ATOM 6471 C CG2 . THR D 2 211 ? 96.821 10.141 -59.856 1.00 143.53 ? 194 THR I CG2 1 ATOM 6472 N N . ASP D 2 212 ? 98.619 13.780 -58.961 1.00 140.29 ? 195 ASP I N 1 ATOM 6473 C CA . ASP D 2 212 ? 99.102 15.150 -58.824 1.00 138.85 ? 195 ASP I CA 1 ATOM 6474 C C . ASP D 2 212 ? 98.064 16.205 -59.232 1.00 137.82 ? 195 ASP I C 1 ATOM 6475 O O . ASP D 2 212 ? 98.386 17.173 -59.924 1.00 138.39 ? 195 ASP I O 1 ATOM 6476 C CB . ASP D 2 212 ? 100.410 15.340 -59.615 1.00 138.78 ? 195 ASP I CB 1 ATOM 6477 C CG . ASP D 2 212 ? 100.487 14.465 -60.861 1.00 138.41 ? 195 ASP I CG 1 ATOM 6478 O OD1 . ASP D 2 212 ? 99.675 14.657 -61.790 1.00 137.99 ? 195 ASP I OD1 1 ATOM 6479 O OD2 . ASP D 2 212 ? 101.370 13.582 -60.910 1.00 138.24 ? 195 ASP I OD2 1 ATOM 6480 N N . GLU D 2 213 ? 96.820 16.010 -58.790 1.00 135.77 ? 196 GLU I N 1 ATOM 6481 C CA . GLU D 2 213 ? 95.724 16.938 -59.083 1.00 132.90 ? 196 GLU I CA 1 ATOM 6482 C C . GLU D 2 213 ? 94.743 17.030 -57.908 1.00 130.61 ? 196 GLU I C 1 ATOM 6483 O O . GLU D 2 213 ? 94.054 16.059 -57.596 1.00 130.52 ? 196 GLU I O 1 ATOM 6484 C CB . GLU D 2 213 ? 94.965 16.501 -60.343 1.00 132.96 ? 196 GLU I CB 1 ATOM 6485 C CG . GLU D 2 213 ? 95.752 16.621 -61.645 1.00 133.03 ? 196 GLU I CG 1 ATOM 6486 C CD . GLU D 2 213 ? 96.697 15.456 -61.883 1.00 132.88 ? 196 GLU I CD 1 ATOM 6487 O OE1 . GLU D 2 213 ? 97.439 15.489 -62.889 1.00 132.32 ? 196 GLU I OE1 1 ATOM 6488 O OE2 . GLU D 2 213 ? 96.693 14.506 -61.069 1.00 132.70 ? 196 GLU I OE2 1 ATOM 6489 N N . HIS D 2 214 ? 94.688 18.208 -57.283 1.00 127.31 ? 197 HIS I N 1 ATOM 6490 C CA . HIS D 2 214 ? 93.825 18.513 -56.131 1.00 124.03 ? 197 HIS I CA 1 ATOM 6491 C C . HIS D 2 214 ? 93.377 17.348 -55.240 1.00 121.87 ? 197 HIS I C 1 ATOM 6492 O O . HIS D 2 214 ? 93.833 16.218 -55.398 1.00 122.01 ? 197 HIS I O 1 ATOM 6493 C CB . HIS D 2 214 ? 92.604 19.337 -56.589 1.00 123.38 ? 197 HIS I CB 1 ATOM 6494 C CG . HIS D 2 214 ? 91.607 18.577 -57.414 1.00 122.95 ? 197 HIS I CG 1 ATOM 6495 N ND1 . HIS D 2 214 ? 90.728 19.205 -58.272 1.00 122.39 ? 197 HIS I ND1 1 ATOM 6496 C CD2 . HIS D 2 214 ? 91.311 17.257 -57.477 1.00 122.88 ? 197 HIS I CD2 1 ATOM 6497 C CE1 . HIS D 2 214 ? 89.935 18.306 -58.826 1.00 122.04 ? 197 HIS I CE1 1 ATOM 6498 N NE2 . HIS D 2 214 ? 90.267 17.116 -58.361 1.00 122.07 ? 197 HIS I NE2 1 ATOM 6499 N N . VAL D 2 215 ? 92.500 17.638 -54.282 1.00 119.09 ? 198 VAL I N 1 ATOM 6500 C CA . VAL D 2 215 ? 92.000 16.616 -53.361 1.00 116.28 ? 198 VAL I CA 1 ATOM 6501 C C . VAL D 2 215 ? 90.548 16.856 -52.939 1.00 114.47 ? 198 VAL I C 1 ATOM 6502 O O . VAL D 2 215 ? 89.926 17.839 -53.342 1.00 114.30 ? 198 VAL I O 1 ATOM 6503 C CB . VAL D 2 215 ? 92.878 16.528 -52.086 1.00 116.30 ? 198 VAL I CB 1 ATOM 6504 C CG1 . VAL D 2 215 ? 94.251 15.976 -52.433 1.00 115.82 ? 198 VAL I CG1 1 ATOM 6505 C CG2 . VAL D 2 215 ? 93.012 17.901 -51.448 1.00 116.19 ? 198 VAL I CG2 1 ATOM 6506 N N . VAL D 2 216 ? 90.014 15.955 -52.121 1.00 111.85 ? 199 VAL I N 1 ATOM 6507 C CA . VAL D 2 216 ? 88.634 16.072 -51.669 1.00 109.64 ? 199 VAL I CA 1 ATOM 6508 C C . VAL D 2 216 ? 88.483 15.987 -50.157 1.00 107.54 ? 199 VAL I C 1 ATOM 6509 O O . VAL D 2 216 ? 88.996 15.068 -49.518 1.00 107.32 ? 199 VAL I O 1 ATOM 6510 C CB . VAL D 2 216 ? 87.751 14.978 -52.319 1.00 110.24 ? 199 VAL I CB 1 ATOM 6511 C CG1 . VAL D 2 216 ? 86.343 15.009 -51.729 1.00 109.72 ? 199 VAL I CG1 1 ATOM 6512 C CG2 . VAL D 2 216 ? 87.698 15.192 -53.827 1.00 110.60 ? 199 VAL I CG2 1 ATOM 6513 N N . CYS D 2 217 ? 87.766 16.956 -49.596 1.00 104.63 ? 200 CYS I N 1 ATOM 6514 C CA . CYS D 2 217 ? 87.523 17.008 -48.160 1.00 101.47 ? 200 CYS I CA 1 ATOM 6515 C C . CYS D 2 217 ? 86.147 16.425 -47.879 1.00 100.61 ? 200 CYS I C 1 ATOM 6516 O O . CYS D 2 217 ? 85.177 16.776 -48.546 1.00 101.07 ? 200 CYS I O 1 ATOM 6517 C CB . CYS D 2 217 ? 87.571 18.457 -47.671 1.00 99.20 ? 200 CYS I CB 1 ATOM 6518 S SG . CYS D 2 217 ? 87.494 18.665 -45.863 1.00 93.63 ? 200 CYS I SG 1 ATOM 6519 N N . LYS D 2 218 ? 86.063 15.538 -46.893 1.00 99.18 ? 201 LYS I N 1 ATOM 6520 C CA . LYS D 2 218 ? 84.795 14.914 -46.535 1.00 98.55 ? 201 LYS I CA 1 ATOM 6521 C C . LYS D 2 218 ? 84.351 15.336 -45.138 1.00 98.22 ? 201 LYS I C 1 ATOM 6522 O O . LYS D 2 218 ? 85.116 15.227 -44.181 1.00 97.80 ? 201 LYS I O 1 ATOM 6523 C CB . LYS D 2 218 ? 84.928 13.388 -46.598 1.00 98.56 ? 201 LYS I CB 1 ATOM 6524 C CG . LYS D 2 218 ? 85.063 12.821 -48.012 1.00 97.77 ? 201 LYS I CG 1 ATOM 6525 C CD . LYS D 2 218 ? 83.714 12.674 -48.710 1.00 95.63 ? 201 LYS I CD 1 ATOM 6526 C CE . LYS D 2 218 ? 82.906 11.529 -48.114 1.00 94.57 ? 201 LYS I CE 1 ATOM 6527 N NZ . LYS D 2 218 ? 82.662 11.695 -46.654 1.00 92.68 ? 201 LYS I NZ 1 ATOM 6528 N N . VAL D 2 219 ? 83.113 15.815 -45.026 1.00 97.89 ? 202 VAL I N 1 ATOM 6529 C CA . VAL D 2 219 ? 82.576 16.256 -43.740 1.00 97.32 ? 202 VAL I CA 1 ATOM 6530 C C . VAL D 2 219 ? 81.242 15.600 -43.399 1.00 96.57 ? 202 VAL I C 1 ATOM 6531 O O . VAL D 2 219 ? 80.318 15.593 -44.210 1.00 96.21 ? 202 VAL I O 1 ATOM 6532 C CB . VAL D 2 219 ? 82.369 17.795 -43.709 1.00 97.48 ? 202 VAL I CB 1 ATOM 6533 C CG1 . VAL D 2 219 ? 81.911 18.235 -42.326 1.00 97.54 ? 202 VAL I CG1 1 ATOM 6534 C CG2 . VAL D 2 219 ? 83.655 18.505 -44.078 1.00 97.85 ? 202 VAL I CG2 1 ATOM 6535 N N . GLN D 2 220 ? 81.153 15.050 -42.192 1.00 96.45 ? 203 GLN I N 1 ATOM 6536 C CA . GLN D 2 220 ? 79.929 14.417 -41.712 1.00 96.81 ? 203 GLN I CA 1 ATOM 6537 C C . GLN D 2 220 ? 79.306 15.398 -40.716 1.00 97.57 ? 203 GLN I C 1 ATOM 6538 O O . GLN D 2 220 ? 80.002 16.259 -40.172 1.00 98.14 ? 203 GLN I O 1 ATOM 6539 C CB . GLN D 2 220 ? 80.245 13.095 -41.005 1.00 96.91 ? 203 GLN I CB 1 ATOM 6540 C CG . GLN D 2 220 ? 81.080 12.109 -41.825 1.00 97.59 ? 203 GLN I CG 1 ATOM 6541 C CD . GLN D 2 220 ? 80.292 11.406 -42.917 1.00 97.17 ? 203 GLN I CD 1 ATOM 6542 O OE1 . GLN D 2 220 ? 79.342 10.670 -42.639 1.00 97.60 ? 203 GLN I OE1 1 ATOM 6543 N NE2 . GLN D 2 220 ? 80.686 11.627 -44.167 1.00 96.11 ? 203 GLN I NE2 1 ATOM 6544 N N . HIS D 2 221 ? 78.003 15.267 -40.481 1.00 97.70 ? 204 HIS I N 1 ATOM 6545 C CA . HIS D 2 221 ? 77.275 16.147 -39.566 1.00 95.83 ? 204 HIS I CA 1 ATOM 6546 C C . HIS D 2 221 ? 75.814 15.705 -39.605 1.00 94.78 ? 204 HIS I C 1 ATOM 6547 O O . HIS D 2 221 ? 75.286 15.384 -40.671 1.00 94.87 ? 204 HIS I O 1 ATOM 6548 C CB . HIS D 2 221 ? 77.395 17.602 -40.040 1.00 96.30 ? 204 HIS I CB 1 ATOM 6549 C CG . HIS D 2 221 ? 76.969 18.617 -39.024 1.00 97.64 ? 204 HIS I CG 1 ATOM 6550 N ND1 . HIS D 2 221 ? 75.734 18.592 -38.413 1.00 98.49 ? 204 HIS I ND1 1 ATOM 6551 C CD2 . HIS D 2 221 ? 77.606 19.709 -38.535 1.00 98.55 ? 204 HIS I CD2 1 ATOM 6552 C CE1 . HIS D 2 221 ? 75.629 19.624 -37.593 1.00 98.39 ? 204 HIS I CE1 1 ATOM 6553 N NE2 . HIS D 2 221 ? 76.751 20.318 -37.648 1.00 97.87 ? 204 HIS I NE2 1 ATOM 6554 N N . PRO D 2 222 ? 75.140 15.668 -38.445 1.00 93.68 ? 205 PRO I N 1 ATOM 6555 C CA . PRO D 2 222 ? 73.736 15.249 -38.446 1.00 92.63 ? 205 PRO I CA 1 ATOM 6556 C C . PRO D 2 222 ? 72.910 16.090 -39.413 1.00 91.68 ? 205 PRO I C 1 ATOM 6557 O O . PRO D 2 222 ? 72.124 15.572 -40.206 1.00 91.83 ? 205 PRO I O 1 ATOM 6558 C CB . PRO D 2 222 ? 73.308 15.473 -36.997 1.00 92.37 ? 205 PRO I CB 1 ATOM 6559 C CG . PRO D 2 222 ? 74.562 15.255 -36.236 1.00 92.08 ? 205 PRO I CG 1 ATOM 6560 C CD . PRO D 2 222 ? 75.591 15.975 -37.076 1.00 93.35 ? 205 PRO I CD 1 ATOM 6561 N N . ASN D 2 223 ? 73.124 17.397 -39.349 1.00 90.15 ? 206 ASN I N 1 ATOM 6562 C CA . ASN D 2 223 ? 72.396 18.347 -40.169 1.00 89.33 ? 206 ASN I CA 1 ATOM 6563 C C . ASN D 2 223 ? 72.957 18.615 -41.568 1.00 88.27 ? 206 ASN I C 1 ATOM 6564 O O . ASN D 2 223 ? 73.108 19.770 -41.966 1.00 88.39 ? 206 ASN I O 1 ATOM 6565 C CB . ASN D 2 223 ? 72.275 19.659 -39.393 1.00 89.77 ? 206 ASN I CB 1 ATOM 6566 C CG . ASN D 2 223 ? 71.628 19.468 -38.035 1.00 89.87 ? 206 ASN I CG 1 ATOM 6567 O OD1 . ASN D 2 223 ? 71.992 18.564 -37.281 1.00 89.54 ? 206 ASN I OD1 1 ATOM 6568 N ND2 . ASN D 2 223 ? 70.666 20.320 -37.716 1.00 90.22 ? 206 ASN I ND2 1 ATOM 6569 N N . GLY D 2 224 ? 73.258 17.553 -42.311 1.00 86.73 ? 207 GLY I N 1 ATOM 6570 C CA . GLY D 2 224 ? 73.766 17.721 -43.664 1.00 85.85 ? 207 GLY I CA 1 ATOM 6571 C C . GLY D 2 224 ? 75.273 17.665 -43.871 1.00 85.18 ? 207 GLY I C 1 ATOM 6572 O O . GLY D 2 224 ? 76.036 18.340 -43.173 1.00 86.02 ? 207 GLY I O 1 ATOM 6573 N N . ASN D 2 225 ? 75.703 16.868 -44.847 1.00 83.35 ? 208 ASN I N 1 ATOM 6574 C CA . ASN D 2 225 ? 77.119 16.737 -45.142 1.00 81.28 ? 208 ASN I CA 1 ATOM 6575 C C . ASN D 2 225 ? 77.591 17.768 -46.148 1.00 82.26 ? 208 ASN I C 1 ATOM 6576 O O . ASN D 2 225 ? 76.831 18.647 -46.557 1.00 81.84 ? 208 ASN I O 1 ATOM 6577 C CB . ASN D 2 225 ? 77.428 15.342 -45.659 1.00 77.98 ? 208 ASN I CB 1 ATOM 6578 C CG . ASN D 2 225 ? 77.132 14.279 -44.640 1.00 77.18 ? 208 ASN I CG 1 ATOM 6579 O OD1 . ASN D 2 225 ? 77.596 13.149 -44.757 1.00 77.46 ? 208 ASN I OD1 1 ATOM 6580 N ND2 . ASN D 2 225 ? 76.350 14.631 -43.630 1.00 75.72 ? 208 ASN I ND2 1 ATOM 6581 N N . LYS D 2 226 ? 78.857 17.657 -46.536 1.00 83.16 ? 209 LYS I N 1 ATOM 6582 C CA . LYS D 2 226 ? 79.463 18.578 -47.486 1.00 84.05 ? 209 LYS I CA 1 ATOM 6583 C C . LYS D 2 226 ? 80.775 18.013 -48.003 1.00 85.15 ? 209 LYS I C 1 ATOM 6584 O O . LYS D 2 226 ? 81.433 17.218 -47.326 1.00 85.08 ? 209 LYS I O 1 ATOM 6585 C CB . LYS D 2 226 ? 79.729 19.931 -46.822 1.00 84.35 ? 209 LYS I CB 1 ATOM 6586 C CG . LYS D 2 226 ? 78.541 20.879 -46.798 1.00 85.83 ? 209 LYS I CG 1 ATOM 6587 C CD . LYS D 2 226 ? 78.153 21.310 -48.210 1.00 86.92 ? 209 LYS I CD 1 ATOM 6588 C CE . LYS D 2 226 ? 77.058 22.366 -48.201 1.00 86.18 ? 209 LYS I CE 1 ATOM 6589 N NZ . LYS D 2 226 ? 77.487 23.616 -47.519 1.00 85.93 ? 209 LYS I NZ 1 ATOM 6590 N N . GLU D 2 227 ? 81.150 18.431 -49.207 1.00 86.57 ? 210 GLU I N 1 ATOM 6591 C CA . GLU D 2 227 ? 82.389 17.988 -49.827 1.00 87.20 ? 210 GLU I CA 1 ATOM 6592 C C . GLU D 2 227 ? 83.046 19.150 -50.530 1.00 86.21 ? 210 GLU I C 1 ATOM 6593 O O . GLU D 2 227 ? 82.388 19.922 -51.222 1.00 85.39 ? 210 GLU I O 1 ATOM 6594 C CB . GLU D 2 227 ? 82.117 16.865 -50.822 1.00 89.77 ? 210 GLU I CB 1 ATOM 6595 C CG . GLU D 2 227 ? 81.718 15.565 -50.152 1.00 94.91 ? 210 GLU I CG 1 ATOM 6596 C CD . GLU D 2 227 ? 81.315 14.498 -51.147 1.00 98.89 ? 210 GLU I CD 1 ATOM 6597 O OE1 . GLU D 2 227 ? 82.114 14.208 -52.069 1.00 101.21 ? 210 GLU I OE1 1 ATOM 6598 O OE2 . GLU D 2 227 ? 80.198 13.950 -51.001 1.00 100.67 ? 210 GLU I OE2 1 ATOM 6599 N N . LYS D 2 228 ? 84.353 19.272 -50.343 1.00 86.86 ? 211 LYS I N 1 ATOM 6600 C CA . LYS D 2 228 ? 85.104 20.356 -50.955 1.00 87.85 ? 211 LYS I CA 1 ATOM 6601 C C . LYS D 2 228 ? 86.352 19.876 -51.683 1.00 89.24 ? 211 LYS I C 1 ATOM 6602 O O . LYS D 2 228 ? 87.101 19.031 -51.180 1.00 89.08 ? 211 LYS I O 1 ATOM 6603 C CB . LYS D 2 228 ? 85.512 21.383 -49.895 1.00 85.92 ? 211 LYS I CB 1 ATOM 6604 C CG . LYS D 2 228 ? 84.935 22.770 -50.096 1.00 82.95 ? 211 LYS I CG 1 ATOM 6605 C CD . LYS D 2 228 ? 85.267 23.333 -51.460 1.00 81.52 ? 211 LYS I CD 1 ATOM 6606 C CE . LYS D 2 228 ? 84.785 24.770 -51.576 1.00 81.28 ? 211 LYS I CE 1 ATOM 6607 N NZ . LYS D 2 228 ? 83.333 24.940 -51.276 1.00 80.72 ? 211 LYS I NZ 1 ATOM 6608 N N . ASN D 2 229 ? 86.558 20.426 -52.875 1.00 91.01 ? 212 ASN I N 1 ATOM 6609 C CA . ASN D 2 229 ? 87.723 20.108 -53.685 1.00 93.01 ? 212 ASN I CA 1 ATOM 6610 C C . ASN D 2 229 ? 88.823 21.085 -53.279 1.00 94.10 ? 212 ASN I C 1 ATOM 6611 O O . ASN D 2 229 ? 88.663 22.310 -53.385 1.00 93.82 ? 212 ASN I O 1 ATOM 6612 C CB . ASN D 2 229 ? 87.415 20.275 -55.182 1.00 93.13 ? 212 ASN I CB 1 ATOM 6613 C CG . ASN D 2 229 ? 86.544 19.161 -55.734 1.00 92.98 ? 212 ASN I CG 1 ATOM 6614 O OD1 . ASN D 2 229 ? 86.976 18.009 -55.842 1.00 92.69 ? 212 ASN I OD1 1 ATOM 6615 N ND2 . ASN D 2 229 ? 85.306 19.499 -56.086 1.00 92.74 ? 212 ASN I ND2 1 ATOM 6616 N N . VAL D 2 230 ? 89.931 20.537 -52.794 1.00 95.04 ? 213 VAL I N 1 ATOM 6617 C CA . VAL D 2 230 ? 91.054 21.359 -52.381 1.00 95.71 ? 213 VAL I CA 1 ATOM 6618 C C . VAL D 2 230 ? 92.164 21.284 -53.416 1.00 96.71 ? 213 VAL I C 1 ATOM 6619 O O . VAL D 2 230 ? 92.939 20.327 -53.450 1.00 96.04 ? 213 VAL I O 1 ATOM 6620 C CB . VAL D 2 230 ? 91.611 20.916 -51.021 1.00 94.97 ? 213 VAL I CB 1 ATOM 6621 C CG1 . VAL D 2 230 ? 92.801 21.793 -50.636 1.00 93.70 ? 213 VAL I CG1 1 ATOM 6622 C CG2 . VAL D 2 230 ? 90.513 20.991 -49.970 1.00 94.44 ? 213 VAL I CG2 1 ATOM 6623 N N . PRO D 2 231 ? 92.240 22.299 -54.288 1.00 97.60 ? 214 PRO I N 1 ATOM 6624 C CA . PRO D 2 231 ? 93.261 22.357 -55.334 1.00 98.02 ? 214 PRO I CA 1 ATOM 6625 C C . PRO D 2 231 ? 94.671 22.364 -54.749 1.00 98.46 ? 214 PRO I C 1 ATOM 6626 O O . PRO D 2 231 ? 95.374 23.376 -54.940 1.00 99.24 ? 214 PRO I O 1 ATOM 6627 C CB . PRO D 2 231 ? 92.919 23.653 -56.073 1.00 98.14 ? 214 PRO I CB 1 ATOM 6628 C CG . PRO D 2 231 ? 92.270 24.496 -55.012 1.00 97.85 ? 214 PRO I CG 1 ATOM 6629 C CD . PRO D 2 231 ? 91.380 23.496 -54.329 1.00 97.80 ? 214 PRO I CD 1 ATOM 6630 O OXT . PRO D 2 231 ? 95.054 21.365 -54.105 1.00 98.35 ? 214 PRO I OXT 1 ATOM 6631 N N . GLN E 3 20 ? 71.068 -22.610 14.590 1.00 84.59 ? 1 GLN L N 1 ATOM 6632 C CA . GLN E 3 20 ? 70.195 -21.582 15.229 1.00 84.94 ? 1 GLN L CA 1 ATOM 6633 C C . GLN E 3 20 ? 70.959 -20.667 16.190 1.00 83.94 ? 1 GLN L C 1 ATOM 6634 O O . GLN E 3 20 ? 70.509 -19.555 16.473 1.00 83.82 ? 1 GLN L O 1 ATOM 6635 C CB . GLN E 3 20 ? 69.059 -22.249 16.008 1.00 86.63 ? 1 GLN L CB 1 ATOM 6636 C CG . GLN E 3 20 ? 69.467 -22.718 17.405 1.00 88.14 ? 1 GLN L CG 1 ATOM 6637 C CD . GLN E 3 20 ? 68.281 -23.115 18.260 1.00 88.89 ? 1 GLN L CD 1 ATOM 6638 O OE1 . GLN E 3 20 ? 67.589 -24.091 17.962 1.00 89.50 ? 1 GLN L OE1 1 ATOM 6639 N NE2 . GLN E 3 20 ? 68.034 -22.353 19.329 1.00 88.80 ? 1 GLN L NE2 1 ATOM 6640 N N . SER E 3 21 ? 72.101 -21.130 16.700 1.00 81.81 ? 2 SER L N 1 ATOM 6641 C CA . SER E 3 21 ? 72.875 -20.325 17.642 1.00 79.15 ? 2 SER L CA 1 ATOM 6642 C C . SER E 3 21 ? 74.389 -20.328 17.483 1.00 77.19 ? 2 SER L C 1 ATOM 6643 O O . SER E 3 21 ? 75.097 -19.885 18.387 1.00 76.64 ? 2 SER L O 1 ATOM 6644 C CB . SER E 3 21 ? 72.535 -20.725 19.083 1.00 79.40 ? 2 SER L CB 1 ATOM 6645 O OG . SER E 3 21 ? 71.549 -19.871 19.631 1.00 78.67 ? 2 SER L OG 1 ATOM 6646 N N . VAL E 3 22 ? 74.900 -20.808 16.356 1.00 74.90 ? 3 VAL L N 1 ATOM 6647 C CA . VAL E 3 22 ? 76.346 -20.802 16.183 1.00 73.40 ? 3 VAL L CA 1 ATOM 6648 C C . VAL E 3 22 ? 76.812 -20.872 14.734 1.00 71.75 ? 3 VAL L C 1 ATOM 6649 O O . VAL E 3 22 ? 76.325 -21.674 13.944 1.00 71.72 ? 3 VAL L O 1 ATOM 6650 C CB . VAL E 3 22 ? 77.013 -21.948 16.985 1.00 73.88 ? 3 VAL L CB 1 ATOM 6651 C CG1 . VAL E 3 22 ? 76.646 -23.298 16.376 1.00 72.37 ? 3 VAL L CG1 1 ATOM 6652 C CG2 . VAL E 3 22 ? 78.538 -21.736 17.032 1.00 73.13 ? 3 VAL L CG2 1 ATOM 6653 N N . LEU E 3 23 ? 77.777 -20.021 14.405 1.00 70.04 ? 4 LEU L N 1 ATOM 6654 C CA . LEU E 3 23 ? 78.331 -19.949 13.065 1.00 68.99 ? 4 LEU L CA 1 ATOM 6655 C C . LEU E 3 23 ? 79.238 -21.143 12.798 1.00 70.16 ? 4 LEU L C 1 ATOM 6656 O O . LEU E 3 23 ? 79.994 -21.581 13.672 1.00 71.30 ? 4 LEU L O 1 ATOM 6657 C CB . LEU E 3 23 ? 79.134 -18.662 12.899 1.00 66.59 ? 4 LEU L CB 1 ATOM 6658 C CG . LEU E 3 23 ? 78.598 -17.457 13.665 1.00 64.67 ? 4 LEU L CG 1 ATOM 6659 C CD1 . LEU E 3 23 ? 79.559 -16.304 13.529 1.00 65.67 ? 4 LEU L CD1 1 ATOM 6660 C CD2 . LEU E 3 23 ? 77.234 -17.079 13.146 1.00 66.30 ? 4 LEU L CD2 1 ATOM 6661 N N . THR E 3 24 ? 79.159 -21.653 11.575 1.00 69.57 ? 5 THR L N 1 ATOM 6662 C CA . THR E 3 24 ? 79.957 -22.787 11.160 1.00 68.27 ? 5 THR L CA 1 ATOM 6663 C C . THR E 3 24 ? 80.739 -22.441 9.913 1.00 68.57 ? 5 THR L C 1 ATOM 6664 O O . THR E 3 24 ? 80.157 -22.070 8.888 1.00 68.02 ? 5 THR L O 1 ATOM 6665 C CB . THR E 3 24 ? 79.080 -23.989 10.825 1.00 68.67 ? 5 THR L CB 1 ATOM 6666 O OG1 . THR E 3 24 ? 78.384 -24.413 11.999 1.00 70.09 ? 5 THR L OG1 1 ATOM 6667 C CG2 . THR E 3 24 ? 79.929 -25.129 10.297 1.00 69.05 ? 5 THR L CG2 1 ATOM 6668 N N . GLN E 3 25 ? 82.059 -22.553 10.006 1.00 68.59 ? 6 GLN L N 1 ATOM 6669 C CA . GLN E 3 25 ? 82.921 -22.298 8.864 1.00 69.20 ? 6 GLN L CA 1 ATOM 6670 C C . GLN E 3 25 ? 83.691 -23.572 8.555 1.00 70.99 ? 6 GLN L C 1 ATOM 6671 O O . GLN E 3 25 ? 83.708 -24.511 9.354 1.00 71.34 ? 6 GLN L O 1 ATOM 6672 C CB . GLN E 3 25 ? 83.904 -21.156 9.142 1.00 66.90 ? 6 GLN L CB 1 ATOM 6673 C CG . GLN E 3 25 ? 83.938 -20.652 10.560 1.00 64.91 ? 6 GLN L CG 1 ATOM 6674 C CD . GLN E 3 25 ? 84.983 -19.566 10.747 1.00 64.83 ? 6 GLN L CD 1 ATOM 6675 O OE1 . GLN E 3 25 ? 85.115 -18.989 11.830 1.00 65.28 ? 6 GLN L OE1 1 ATOM 6676 N NE2 . GLN E 3 25 ? 85.738 -19.285 9.689 1.00 62.50 ? 6 GLN L NE2 1 ATOM 6677 N N . PRO E 3 26 ? 84.327 -23.633 7.376 1.00 72.72 ? 7 PRO L N 1 ATOM 6678 C CA . PRO E 3 26 ? 85.086 -24.833 7.029 1.00 73.01 ? 7 PRO L CA 1 ATOM 6679 C C . PRO E 3 26 ? 86.335 -24.951 7.906 1.00 73.80 ? 7 PRO L C 1 ATOM 6680 O O . PRO E 3 26 ? 87.159 -24.031 7.978 1.00 73.77 ? 7 PRO L O 1 ATOM 6681 C CB . PRO E 3 26 ? 85.425 -24.606 5.560 1.00 72.61 ? 7 PRO L CB 1 ATOM 6682 C CG . PRO E 3 26 ? 85.608 -23.122 5.499 1.00 72.64 ? 7 PRO L CG 1 ATOM 6683 C CD . PRO E 3 26 ? 84.425 -22.622 6.308 1.00 72.91 ? 7 PRO L CD 1 ATOM 6684 N N . PRO E 3 27 ? 86.483 -26.090 8.595 1.00 73.69 ? 8 PRO L N 1 ATOM 6685 C CA . PRO E 3 27 ? 87.637 -26.323 9.467 1.00 73.05 ? 8 PRO L CA 1 ATOM 6686 C C . PRO E 3 27 ? 88.969 -25.916 8.837 1.00 71.82 ? 8 PRO L C 1 ATOM 6687 O O . PRO E 3 27 ? 89.912 -25.568 9.544 1.00 71.05 ? 8 PRO L O 1 ATOM 6688 C CB . PRO E 3 27 ? 87.554 -27.821 9.735 1.00 72.73 ? 8 PRO L CB 1 ATOM 6689 C CG . PRO E 3 27 ? 86.072 -28.045 9.792 1.00 73.13 ? 8 PRO L CG 1 ATOM 6690 C CD . PRO E 3 27 ? 85.571 -27.249 8.604 1.00 73.02 ? 8 PRO L CD 1 ATOM 6691 N N . SER E 3 28 ? 89.036 -25.946 7.511 1.00 71.41 ? 9 SER L N 1 ATOM 6692 C CA . SER E 3 28 ? 90.263 -25.597 6.809 1.00 72.72 ? 9 SER L CA 1 ATOM 6693 C C . SER E 3 28 ? 89.990 -25.167 5.374 1.00 72.23 ? 9 SER L C 1 ATOM 6694 O O . SER E 3 28 ? 88.882 -25.341 4.883 1.00 71.08 ? 9 SER L O 1 ATOM 6695 C CB . SER E 3 28 ? 91.207 -26.798 6.833 1.00 74.70 ? 9 SER L CB 1 ATOM 6696 O OG . SER E 3 28 ? 90.476 -28.015 6.768 1.00 75.42 ? 9 SER L OG 1 ATOM 6697 N N . ALA E 3 29 ? 90.999 -24.617 4.702 1.00 72.62 ? 10 ALA L N 1 ATOM 6698 C CA . ALA E 3 29 ? 90.813 -24.160 3.327 1.00 74.35 ? 10 ALA L CA 1 ATOM 6699 C C . ALA E 3 29 ? 91.963 -24.466 2.358 1.00 76.60 ? 10 ALA L C 1 ATOM 6700 O O . ALA E 3 29 ? 91.829 -25.341 1.495 1.00 77.67 ? 10 ALA L O 1 ATOM 6701 C CB . ALA E 3 29 ? 90.524 -22.674 3.326 1.00 73.83 ? 10 ALA L CB 1 ATOM 6702 N N . SER E 3 30 ? 93.069 -23.726 2.481 1.00 77.39 ? 11 SER L N 1 ATOM 6703 C CA . SER E 3 30 ? 94.258 -23.901 1.630 1.00 78.90 ? 11 SER L CA 1 ATOM 6704 C C . SER E 3 30 ? 94.069 -23.633 0.129 1.00 79.99 ? 11 SER L C 1 ATOM 6705 O O . SER E 3 30 ? 93.038 -23.964 -0.453 1.00 79.38 ? 11 SER L O 1 ATOM 6706 C CB . SER E 3 30 ? 94.822 -25.317 1.785 1.00 79.57 ? 11 SER L CB 1 ATOM 6707 O OG . SER E 3 30 ? 94.197 -26.225 0.883 1.00 78.55 ? 11 SER L OG 1 ATOM 6708 N N . GLY E 3 31 ? 95.092 -23.054 -0.493 1.00 81.47 ? 12 GLY L N 1 ATOM 6709 C CA . GLY E 3 31 ? 95.046 -22.769 -1.919 1.00 84.60 ? 12 GLY L CA 1 ATOM 6710 C C . GLY E 3 31 ? 96.445 -22.795 -2.518 1.00 86.17 ? 12 GLY L C 1 ATOM 6711 O O . GLY E 3 31 ? 97.246 -23.668 -2.173 1.00 88.13 ? 12 GLY L O 1 ATOM 6712 N N . THR E 3 32 ? 96.735 -21.862 -3.426 1.00 86.05 ? 13 THR L N 1 ATOM 6713 C CA . THR E 3 32 ? 98.061 -21.748 -4.048 1.00 85.94 ? 13 THR L CA 1 ATOM 6714 C C . THR E 3 32 ? 98.241 -20.297 -4.485 1.00 85.40 ? 13 THR L C 1 ATOM 6715 O O . THR E 3 32 ? 97.327 -19.704 -5.051 1.00 85.62 ? 13 THR L O 1 ATOM 6716 C CB . THR E 3 32 ? 98.229 -22.671 -5.284 1.00 86.32 ? 13 THR L CB 1 ATOM 6717 O OG1 . THR E 3 32 ? 98.266 -21.869 -6.473 1.00 86.20 ? 13 THR L OG1 1 ATOM 6718 C CG2 . THR E 3 32 ? 97.088 -23.696 -5.366 1.00 85.48 ? 13 THR L CG2 1 ATOM 6719 N N . PRO E 3 33 ? 99.435 -19.719 -4.260 1.00 85.26 ? 14 PRO L N 1 ATOM 6720 C CA . PRO E 3 33 ? 99.743 -18.324 -4.616 1.00 84.80 ? 14 PRO L CA 1 ATOM 6721 C C . PRO E 3 33 ? 99.076 -17.775 -5.874 1.00 84.04 ? 14 PRO L C 1 ATOM 6722 O O . PRO E 3 33 ? 98.728 -18.528 -6.785 1.00 84.51 ? 14 PRO L O 1 ATOM 6723 C CB . PRO E 3 33 ? 101.272 -18.313 -4.705 1.00 84.70 ? 14 PRO L CB 1 ATOM 6724 C CG . PRO E 3 33 ? 101.617 -19.737 -5.008 1.00 85.07 ? 14 PRO L CG 1 ATOM 6725 C CD . PRO E 3 33 ? 100.680 -20.487 -4.102 1.00 85.34 ? 14 PRO L CD 1 ATOM 6726 N N . GLY E 3 34 ? 98.894 -16.454 -5.899 1.00 83.03 ? 15 GLY L N 1 ATOM 6727 C CA . GLY E 3 34 ? 98.271 -15.782 -7.032 1.00 82.05 ? 15 GLY L CA 1 ATOM 6728 C C . GLY E 3 34 ? 96.792 -16.081 -7.238 1.00 81.40 ? 15 GLY L C 1 ATOM 6729 O O . GLY E 3 34 ? 96.088 -15.320 -7.904 1.00 81.58 ? 15 GLY L O 1 ATOM 6730 N N . GLN E 3 35 ? 96.325 -17.182 -6.652 1.00 79.99 ? 16 GLN L N 1 ATOM 6731 C CA . GLN E 3 35 ? 94.940 -17.635 -6.759 1.00 78.49 ? 16 GLN L CA 1 ATOM 6732 C C . GLN E 3 35 ? 93.922 -16.794 -5.974 1.00 78.34 ? 16 GLN L C 1 ATOM 6733 O O . GLN E 3 35 ? 94.183 -15.646 -5.606 1.00 78.40 ? 16 GLN L O 1 ATOM 6734 C CB . GLN E 3 35 ? 94.869 -19.083 -6.286 1.00 78.78 ? 16 GLN L CB 1 ATOM 6735 C CG . GLN E 3 35 ? 93.598 -19.811 -6.619 1.00 80.35 ? 16 GLN L CG 1 ATOM 6736 C CD . GLN E 3 35 ? 93.461 -21.078 -5.817 1.00 81.95 ? 16 GLN L CD 1 ATOM 6737 O OE1 . GLN E 3 35 ? 94.432 -21.818 -5.637 1.00 81.81 ? 16 GLN L OE1 1 ATOM 6738 N NE2 . GLN E 3 35 ? 92.252 -21.344 -5.330 1.00 83.10 ? 16 GLN L NE2 1 ATOM 6739 N N . ARG E 3 36 ? 92.757 -17.387 -5.720 1.00 77.58 ? 17 ARG L N 1 ATOM 6740 C CA . ARG E 3 36 ? 91.672 -16.729 -4.996 1.00 75.75 ? 17 ARG L CA 1 ATOM 6741 C C . ARG E 3 36 ? 90.814 -17.779 -4.291 1.00 74.54 ? 17 ARG L C 1 ATOM 6742 O O . ARG E 3 36 ? 90.358 -18.742 -4.908 1.00 72.25 ? 17 ARG L O 1 ATOM 6743 C CB . ARG E 3 36 ? 90.821 -15.914 -5.973 1.00 75.40 ? 17 ARG L CB 1 ATOM 6744 C CG . ARG E 3 36 ? 89.699 -15.109 -5.343 1.00 76.79 ? 17 ARG L CG 1 ATOM 6745 C CD . ARG E 3 36 ? 88.350 -15.827 -5.406 1.00 76.31 ? 17 ARG L CD 1 ATOM 6746 N NE . ARG E 3 36 ? 87.243 -14.903 -5.152 1.00 75.30 ? 17 ARG L NE 1 ATOM 6747 C CZ . ARG E 3 36 ? 85.955 -15.232 -5.204 1.00 73.79 ? 17 ARG L CZ 1 ATOM 6748 N NH1 . ARG E 3 36 ? 85.591 -16.472 -5.504 1.00 72.02 ? 17 ARG L NH1 1 ATOM 6749 N NH2 . ARG E 3 36 ? 85.030 -14.321 -4.942 1.00 72.61 ? 17 ARG L NH2 1 ATOM 6750 N N . VAL E 3 37 ? 90.606 -17.581 -2.992 1.00 74.31 ? 18 VAL L N 1 ATOM 6751 C CA . VAL E 3 37 ? 89.824 -18.504 -2.173 1.00 73.15 ? 18 VAL L CA 1 ATOM 6752 C C . VAL E 3 37 ? 88.742 -17.807 -1.361 1.00 71.83 ? 18 VAL L C 1 ATOM 6753 O O . VAL E 3 37 ? 88.825 -16.603 -1.096 1.00 71.64 ? 18 VAL L O 1 ATOM 6754 C CB . VAL E 3 37 ? 90.730 -19.264 -1.200 1.00 73.42 ? 18 VAL L CB 1 ATOM 6755 C CG1 . VAL E 3 37 ? 91.559 -20.277 -1.956 1.00 75.41 ? 18 VAL L CG1 1 ATOM 6756 C CG2 . VAL E 3 37 ? 91.646 -18.283 -0.483 1.00 73.59 ? 18 VAL L CG2 1 ATOM 6757 N N . THR E 3 38 ? 87.737 -18.582 -0.959 1.00 70.01 ? 19 THR L N 1 ATOM 6758 C CA . THR E 3 38 ? 86.611 -18.067 -0.183 1.00 68.24 ? 19 THR L CA 1 ATOM 6759 C C . THR E 3 38 ? 86.336 -18.913 1.045 1.00 67.36 ? 19 THR L C 1 ATOM 6760 O O . THR E 3 38 ? 86.403 -20.139 0.998 1.00 67.86 ? 19 THR L O 1 ATOM 6761 C CB . THR E 3 38 ? 85.302 -18.072 -0.991 1.00 68.41 ? 19 THR L CB 1 ATOM 6762 O OG1 . THR E 3 38 ? 84.846 -19.425 -1.157 1.00 66.90 ? 19 THR L OG1 1 ATOM 6763 C CG2 . THR E 3 38 ? 85.511 -17.435 -2.352 1.00 69.43 ? 19 THR L CG2 1 ATOM 6764 N N . ILE E 3 39 ? 86.001 -18.257 2.144 1.00 65.88 ? 20 ILE L N 1 ATOM 6765 C CA . ILE E 3 39 ? 85.687 -18.981 3.362 1.00 64.72 ? 20 ILE L CA 1 ATOM 6766 C C . ILE E 3 39 ? 84.252 -18.607 3.755 1.00 64.09 ? 20 ILE L C 1 ATOM 6767 O O . ILE E 3 39 ? 83.923 -17.427 3.857 1.00 64.37 ? 20 ILE L O 1 ATOM 6768 C CB . ILE E 3 39 ? 86.698 -18.628 4.486 1.00 63.00 ? 20 ILE L CB 1 ATOM 6769 C CG1 . ILE E 3 39 ? 88.120 -18.933 4.011 1.00 61.04 ? 20 ILE L CG1 1 ATOM 6770 C CG2 . ILE E 3 39 ? 86.418 -19.455 5.722 1.00 62.59 ? 20 ILE L CG2 1 ATOM 6771 C CD1 . ILE E 3 39 ? 89.182 -18.615 5.011 1.00 59.24 ? 20 ILE L CD1 1 ATOM 6772 N N . SER E 3 40 ? 83.398 -19.612 3.941 1.00 62.80 ? 21 SER L N 1 ATOM 6773 C CA . SER E 3 40 ? 82.001 -19.376 4.305 1.00 61.53 ? 21 SER L CA 1 ATOM 6774 C C . SER E 3 40 ? 81.739 -19.464 5.813 1.00 62.22 ? 21 SER L C 1 ATOM 6775 O O . SER E 3 40 ? 82.481 -20.104 6.559 1.00 61.76 ? 21 SER L O 1 ATOM 6776 C CB . SER E 3 40 ? 81.086 -20.368 3.576 1.00 59.03 ? 21 SER L CB 1 ATOM 6777 O OG . SER E 3 40 ? 81.138 -21.647 4.176 1.00 55.80 ? 21 SER L OG 1 ATOM 6778 N N . CYS E 3 41 ? 80.661 -18.818 6.242 1.00 62.16 ? 22 CYS L N 1 ATOM 6779 C CA . CYS E 3 41 ? 80.260 -18.793 7.645 1.00 61.90 ? 22 CYS L CA 1 ATOM 6780 C C . CYS E 3 41 ? 78.759 -19.064 7.672 1.00 61.24 ? 22 CYS L C 1 ATOM 6781 O O . CYS E 3 41 ? 77.959 -18.147 7.545 1.00 61.48 ? 22 CYS L O 1 ATOM 6782 C CB . CYS E 3 41 ? 80.567 -17.408 8.216 1.00 62.18 ? 22 CYS L CB 1 ATOM 6783 S SG . CYS E 3 41 ? 80.172 -17.025 9.962 1.00 61.44 ? 22 CYS L SG 1 ATOM 6784 N N . SER E 3 42 ? 78.376 -20.325 7.815 1.00 60.51 ? 23 SER L N 1 ATOM 6785 C CA . SER E 3 42 ? 76.964 -20.668 7.835 1.00 60.34 ? 23 SER L CA 1 ATOM 6786 C C . SER E 3 42 ? 76.356 -20.374 9.191 1.00 61.24 ? 23 SER L C 1 ATOM 6787 O O . SER E 3 42 ? 76.749 -20.965 10.196 1.00 61.94 ? 23 SER L O 1 ATOM 6788 C CB . SER E 3 42 ? 76.782 -22.143 7.504 1.00 61.34 ? 23 SER L CB 1 ATOM 6789 O OG . SER E 3 42 ? 75.433 -22.538 7.685 1.00 63.25 ? 23 SER L OG 1 ATOM 6790 N N . GLY E 3 43 ? 75.383 -19.472 9.221 1.00 61.66 ? 24 GLY L N 1 ATOM 6791 C CA . GLY E 3 43 ? 74.762 -19.123 10.485 1.00 61.74 ? 24 GLY L CA 1 ATOM 6792 C C . GLY E 3 43 ? 73.257 -19.293 10.562 1.00 62.03 ? 24 GLY L C 1 ATOM 6793 O O . GLY E 3 43 ? 72.663 -20.086 9.827 1.00 61.54 ? 24 GLY L O 1 ATOM 6794 N N . SER E 3 44 ? 72.645 -18.522 11.459 1.00 62.59 ? 25 SER L N 1 ATOM 6795 C CA . SER E 3 44 ? 71.204 -18.568 11.686 1.00 61.74 ? 25 SER L CA 1 ATOM 6796 C C . SER E 3 44 ? 70.554 -17.196 11.522 1.00 60.68 ? 25 SER L C 1 ATOM 6797 O O . SER E 3 44 ? 71.223 -16.201 11.259 1.00 59.92 ? 25 SER L O 1 ATOM 6798 C CB . SER E 3 44 ? 70.939 -19.095 13.096 1.00 62.90 ? 25 SER L CB 1 ATOM 6799 O OG . SER E 3 44 ? 71.855 -20.138 13.419 1.00 64.09 ? 25 SER L OG 1 ATOM 6800 N N . SER E 3 45 ? 69.241 -17.143 11.684 1.00 60.66 ? 26 SER L N 1 ATOM 6801 C CA . SER E 3 45 ? 68.530 -15.880 11.547 1.00 59.54 ? 26 SER L CA 1 ATOM 6802 C C . SER E 3 45 ? 68.721 -15.075 12.815 1.00 57.93 ? 26 SER L C 1 ATOM 6803 O O . SER E 3 45 ? 68.685 -13.851 12.798 1.00 58.74 ? 26 SER L O 1 ATOM 6804 C CB . SER E 3 45 ? 67.031 -16.116 11.324 1.00 59.65 ? 26 SER L CB 1 ATOM 6805 O OG . SER E 3 45 ? 66.373 -16.430 12.540 1.00 59.29 ? 26 SER L OG 1 ATOM 6806 N N . SER E 3 46 ? 68.916 -15.773 13.920 1.00 56.08 ? 27 SER L N 1 ATOM 6807 C CA . SER E 3 46 ? 69.107 -15.110 15.195 1.00 55.62 ? 27 SER L CA 1 ATOM 6808 C C . SER E 3 46 ? 70.472 -14.439 15.287 1.00 53.62 ? 27 SER L C 1 ATOM 6809 O O . SER E 3 46 ? 70.785 -13.808 16.298 1.00 53.95 ? 27 SER L O 1 ATOM 6810 C CB . SER E 3 46 ? 68.959 -16.123 16.327 1.00 58.56 ? 27 SER L CB 1 ATOM 6811 O OG . SER E 3 46 ? 69.691 -17.305 16.037 1.00 64.02 ? 27 SER L OG 1 ATOM 6812 N N . ASN E 3 47 A 71.283 -14.571 14.241 1.00 50.76 ? 27 ASN L N 1 ATOM 6813 C CA . ASN E 3 47 A 72.610 -13.973 14.252 1.00 48.61 ? 27 ASN L CA 1 ATOM 6814 C C . ASN E 3 47 A 73.105 -13.420 12.932 1.00 48.40 ? 27 ASN L C 1 ATOM 6815 O O . ASN E 3 47 A 72.758 -12.317 12.522 1.00 47.78 ? 27 ASN L O 1 ATOM 6816 C CB . ASN E 3 47 A 73.656 -14.970 14.775 1.00 47.58 ? 27 ASN L CB 1 ATOM 6817 C CG . ASN E 3 47 A 73.507 -16.369 14.175 1.00 48.82 ? 27 ASN L CG 1 ATOM 6818 O OD1 . ASN E 3 47 A 72.759 -17.200 14.702 1.00 49.81 ? 27 ASN L OD1 1 ATOM 6819 N ND2 . ASN E 3 47 A 74.218 -16.637 13.077 1.00 44.24 ? 27 ASN L ND2 1 ATOM 6820 N N . ILE E 3 48 ? 73.942 -14.207 12.278 1.00 49.05 ? 28 ILE L N 1 ATOM 6821 C CA . ILE E 3 48 ? 74.556 -13.826 11.025 1.00 49.43 ? 28 ILE L CA 1 ATOM 6822 C C . ILE E 3 48 ? 73.564 -13.370 9.984 1.00 48.30 ? 28 ILE L C 1 ATOM 6823 O O . ILE E 3 48 ? 73.963 -12.859 8.953 1.00 48.37 ? 28 ILE L O 1 ATOM 6824 C CB . ILE E 3 48 ? 75.392 -14.994 10.457 1.00 51.49 ? 28 ILE L CB 1 ATOM 6825 C CG1 . ILE E 3 48 ? 76.404 -14.474 9.449 1.00 53.13 ? 28 ILE L CG1 1 ATOM 6826 C CG2 . ILE E 3 48 ? 74.497 -15.999 9.771 1.00 50.63 ? 28 ILE L CG2 1 ATOM 6827 C CD1 . ILE E 3 48 ? 77.303 -15.560 8.909 1.00 54.67 ? 28 ILE L CD1 1 ATOM 6828 N N . GLY E 3 49 ? 72.277 -13.552 10.258 1.00 49.14 ? 29 GLY L N 1 ATOM 6829 C CA . GLY E 3 49 ? 71.246 -13.150 9.312 1.00 49.75 ? 29 GLY L CA 1 ATOM 6830 C C . GLY E 3 49 ? 70.596 -11.802 9.598 1.00 51.05 ? 29 GLY L C 1 ATOM 6831 O O . GLY E 3 49 ? 69.915 -11.235 8.735 1.00 51.00 ? 29 GLY L O 1 ATOM 6832 N N . SER E 3 50 ? 70.818 -11.277 10.801 1.00 51.60 ? 30 SER L N 1 ATOM 6833 C CA . SER E 3 50 ? 70.238 -10.001 11.194 1.00 51.13 ? 30 SER L CA 1 ATOM 6834 C C . SER E 3 50 ? 71.228 -8.990 11.744 1.00 50.06 ? 30 SER L C 1 ATOM 6835 O O . SER E 3 50 ? 70.820 -7.926 12.202 1.00 50.86 ? 30 SER L O 1 ATOM 6836 C CB . SER E 3 50 ? 69.130 -10.224 12.226 1.00 53.25 ? 30 SER L CB 1 ATOM 6837 O OG . SER E 3 50 ? 68.047 -10.940 11.653 1.00 57.33 ? 30 SER L OG 1 ATOM 6838 N N . ASN E 3 51 ? 72.519 -9.306 11.712 1.00 48.58 ? 31 ASN L N 1 ATOM 6839 C CA . ASN E 3 51 ? 73.520 -8.370 12.221 1.00 46.01 ? 31 ASN L CA 1 ATOM 6840 C C . ASN E 3 51 ? 74.734 -8.300 11.333 1.00 44.35 ? 31 ASN L C 1 ATOM 6841 O O . ASN E 3 51 ? 74.906 -9.121 10.440 1.00 43.56 ? 31 ASN L O 1 ATOM 6842 C CB . ASN E 3 51 ? 73.965 -8.767 13.612 1.00 46.25 ? 31 ASN L CB 1 ATOM 6843 C CG . ASN E 3 51 ? 72.814 -9.023 14.520 1.00 45.54 ? 31 ASN L CG 1 ATOM 6844 O OD1 . ASN E 3 51 ? 71.942 -9.833 14.220 1.00 46.63 ? 31 ASN L OD1 1 ATOM 6845 N ND2 . ASN E 3 51 ? 72.798 -8.343 15.647 1.00 48.09 ? 31 ASN L ND2 1 ATOM 6846 N N . TYR E 3 52 ? 75.583 -7.312 11.587 1.00 43.53 ? 32 TYR L N 1 ATOM 6847 C CA . TYR E 3 52 ? 76.786 -7.147 10.792 1.00 42.63 ? 32 TYR L CA 1 ATOM 6848 C C . TYR E 3 52 ? 77.769 -8.259 11.103 1.00 42.92 ? 32 TYR L C 1 ATOM 6849 O O . TYR E 3 52 ? 77.914 -8.675 12.249 1.00 42.17 ? 32 TYR L O 1 ATOM 6850 C CB . TYR E 3 52 ? 77.450 -5.812 11.085 1.00 42.40 ? 32 TYR L CB 1 ATOM 6851 C CG . TYR E 3 52 ? 76.615 -4.598 10.778 1.00 42.21 ? 32 TYR L CG 1 ATOM 6852 C CD1 . TYR E 3 52 ? 75.841 -3.983 11.761 1.00 41.52 ? 32 TYR L CD1 1 ATOM 6853 C CD2 . TYR E 3 52 ? 76.631 -4.038 9.509 1.00 43.53 ? 32 TYR L CD2 1 ATOM 6854 C CE1 . TYR E 3 52 ? 75.109 -2.830 11.480 1.00 44.18 ? 32 TYR L CE1 1 ATOM 6855 C CE2 . TYR E 3 52 ? 75.904 -2.885 9.215 1.00 44.07 ? 32 TYR L CE2 1 ATOM 6856 C CZ . TYR E 3 52 ? 75.154 -2.288 10.199 1.00 44.11 ? 32 TYR L CZ 1 ATOM 6857 O OH . TYR E 3 52 ? 74.494 -1.131 9.893 1.00 43.12 ? 32 TYR L OH 1 ATOM 6858 N N . VAL E 3 53 ? 78.442 -8.737 10.069 1.00 42.60 ? 33 VAL L N 1 ATOM 6859 C CA . VAL E 3 53 ? 79.423 -9.788 10.231 1.00 43.02 ? 33 VAL L CA 1 ATOM 6860 C C . VAL E 3 53 ? 80.820 -9.191 10.318 1.00 43.18 ? 33 VAL L C 1 ATOM 6861 O O . VAL E 3 53 ? 81.108 -8.163 9.697 1.00 42.83 ? 33 VAL L O 1 ATOM 6862 C CB . VAL E 3 53 ? 79.338 -10.776 9.055 1.00 44.57 ? 33 VAL L CB 1 ATOM 6863 C CG1 . VAL E 3 53 ? 80.536 -11.718 9.055 1.00 42.89 ? 33 VAL L CG1 1 ATOM 6864 C CG2 . VAL E 3 53 ? 78.026 -11.560 9.151 1.00 43.65 ? 33 VAL L CG2 1 ATOM 6865 N N . TYR E 3 54 ? 81.676 -9.825 11.112 1.00 43.64 ? 34 TYR L N 1 ATOM 6866 C CA . TYR E 3 54 ? 83.055 -9.374 11.272 1.00 45.89 ? 34 TYR L CA 1 ATOM 6867 C C . TYR E 3 54 ? 84.020 -10.495 10.910 1.00 48.26 ? 34 TYR L C 1 ATOM 6868 O O . TYR E 3 54 ? 83.726 -11.670 11.143 1.00 50.15 ? 34 TYR L O 1 ATOM 6869 C CB . TYR E 3 54 ? 83.296 -8.942 12.709 1.00 45.81 ? 34 TYR L CB 1 ATOM 6870 C CG . TYR E 3 54 ? 82.781 -7.570 13.010 1.00 44.96 ? 34 TYR L CG 1 ATOM 6871 C CD1 . TYR E 3 54 ? 83.625 -6.475 12.959 1.00 45.54 ? 34 TYR L CD1 1 ATOM 6872 C CD2 . TYR E 3 54 ? 81.437 -7.356 13.287 1.00 47.05 ? 34 TYR L CD2 1 ATOM 6873 C CE1 . TYR E 3 54 ? 83.151 -5.193 13.172 1.00 48.21 ? 34 TYR L CE1 1 ATOM 6874 C CE2 . TYR E 3 54 ? 80.941 -6.069 13.499 1.00 49.70 ? 34 TYR L CE2 1 ATOM 6875 C CZ . TYR E 3 54 ? 81.808 -4.988 13.438 1.00 49.50 ? 34 TYR L CZ 1 ATOM 6876 O OH . TYR E 3 54 ? 81.348 -3.697 13.616 1.00 50.58 ? 34 TYR L OH 1 ATOM 6877 N N . TRP E 3 55 ? 85.160 -10.140 10.326 1.00 49.56 ? 35 TRP L N 1 ATOM 6878 C CA . TRP E 3 55 ? 86.157 -11.139 9.956 1.00 51.85 ? 35 TRP L CA 1 ATOM 6879 C C . TRP E 3 55 ? 87.530 -10.809 10.520 1.00 52.49 ? 35 TRP L C 1 ATOM 6880 O O . TRP E 3 55 ? 88.092 -9.761 10.214 1.00 52.85 ? 35 TRP L O 1 ATOM 6881 C CB . TRP E 3 55 ? 86.262 -11.271 8.438 1.00 54.62 ? 35 TRP L CB 1 ATOM 6882 C CG . TRP E 3 55 ? 85.124 -12.002 7.837 1.00 58.13 ? 35 TRP L CG 1 ATOM 6883 C CD1 . TRP E 3 55 ? 83.980 -11.462 7.334 1.00 59.70 ? 35 TRP L CD1 1 ATOM 6884 C CD2 . TRP E 3 55 ? 84.965 -13.422 7.766 1.00 60.04 ? 35 TRP L CD2 1 ATOM 6885 N NE1 . TRP E 3 55 ? 83.109 -12.459 6.960 1.00 61.41 ? 35 TRP L NE1 1 ATOM 6886 C CE2 . TRP E 3 55 ? 83.688 -13.672 7.216 1.00 60.14 ? 35 TRP L CE2 1 ATOM 6887 C CE3 . TRP E 3 55 ? 85.774 -14.508 8.122 1.00 60.81 ? 35 TRP L CE3 1 ATOM 6888 C CZ2 . TRP E 3 55 ? 83.198 -14.963 7.013 1.00 60.23 ? 35 TRP L CZ2 1 ATOM 6889 C CZ3 . TRP E 3 55 ? 85.285 -15.794 7.922 1.00 62.24 ? 35 TRP L CZ3 1 ATOM 6890 C CH2 . TRP E 3 55 ? 84.005 -16.009 7.371 1.00 62.00 ? 35 TRP L CH2 1 ATOM 6891 N N . TYR E 3 56 ? 88.066 -11.703 11.347 1.00 52.40 ? 36 TYR L N 1 ATOM 6892 C CA . TYR E 3 56 ? 89.382 -11.493 11.934 1.00 52.37 ? 36 TYR L CA 1 ATOM 6893 C C . TYR E 3 56 ? 90.371 -12.516 11.397 1.00 53.77 ? 36 TYR L C 1 ATOM 6894 O O . TYR E 3 56 ? 90.026 -13.681 11.154 1.00 51.73 ? 36 TYR L O 1 ATOM 6895 C CB . TYR E 3 56 ? 89.325 -11.615 13.457 1.00 50.29 ? 36 TYR L CB 1 ATOM 6896 C CG . TYR E 3 56 ? 88.276 -10.752 14.113 1.00 50.44 ? 36 TYR L CG 1 ATOM 6897 C CD1 . TYR E 3 56 ? 88.488 -9.394 14.316 1.00 50.38 ? 36 TYR L CD1 1 ATOM 6898 C CD2 . TYR E 3 56 ? 87.060 -11.297 14.528 1.00 49.83 ? 36 TYR L CD2 1 ATOM 6899 C CE1 . TYR E 3 56 ? 87.509 -8.597 14.923 1.00 49.93 ? 36 TYR L CE1 1 ATOM 6900 C CE2 . TYR E 3 56 ? 86.078 -10.511 15.130 1.00 48.19 ? 36 TYR L CE2 1 ATOM 6901 C CZ . TYR E 3 56 ? 86.309 -9.165 15.328 1.00 48.45 ? 36 TYR L CZ 1 ATOM 6902 O OH . TYR E 3 56 ? 85.354 -8.393 15.950 1.00 47.98 ? 36 TYR L OH 1 ATOM 6903 N N . GLN E 3 57 ? 91.607 -12.058 11.220 1.00 56.44 ? 37 GLN L N 1 ATOM 6904 C CA . GLN E 3 57 ? 92.705 -12.891 10.742 1.00 57.99 ? 37 GLN L CA 1 ATOM 6905 C C . GLN E 3 57 ? 93.655 -13.158 11.908 1.00 58.27 ? 37 GLN L C 1 ATOM 6906 O O . GLN E 3 57 ? 93.913 -12.265 12.715 1.00 58.26 ? 37 GLN L O 1 ATOM 6907 C CB . GLN E 3 57 ? 93.462 -12.169 9.636 1.00 58.70 ? 37 GLN L CB 1 ATOM 6908 C CG . GLN E 3 57 ? 94.661 -12.929 9.122 1.00 60.30 ? 37 GLN L CG 1 ATOM 6909 C CD . GLN E 3 57 ? 95.599 -12.046 8.330 1.00 61.37 ? 37 GLN L CD 1 ATOM 6910 O OE1 . GLN E 3 57 ? 96.188 -11.102 8.871 1.00 60.73 ? 37 GLN L OE1 1 ATOM 6911 N NE2 . GLN E 3 57 ? 95.743 -12.341 7.039 1.00 62.20 ? 37 GLN L NE2 1 ATOM 6912 N N . GLN E 3 58 ? 94.169 -14.381 12.001 1.00 59.45 ? 38 GLN L N 1 ATOM 6913 C CA . GLN E 3 58 ? 95.093 -14.736 13.079 1.00 61.29 ? 38 GLN L CA 1 ATOM 6914 C C . GLN E 3 58 ? 96.308 -15.535 12.601 1.00 62.99 ? 38 GLN L C 1 ATOM 6915 O O . GLN E 3 58 ? 96.240 -16.761 12.472 1.00 61.91 ? 38 GLN L O 1 ATOM 6916 C CB . GLN E 3 58 ? 94.366 -15.532 14.172 1.00 60.41 ? 38 GLN L CB 1 ATOM 6917 C CG . GLN E 3 58 ? 95.246 -15.904 15.367 1.00 59.21 ? 38 GLN L CG 1 ATOM 6918 C CD . GLN E 3 58 ? 94.500 -16.663 16.464 1.00 59.46 ? 38 GLN L CD 1 ATOM 6919 O OE1 . GLN E 3 58 ? 93.930 -17.741 16.231 1.00 57.95 ? 38 GLN L OE1 1 ATOM 6920 N NE2 . GLN E 3 58 ? 94.510 -16.104 17.672 1.00 57.63 ? 38 GLN L NE2 1 ATOM 6921 N N . LEU E 3 59 ? 97.413 -14.834 12.339 1.00 65.46 ? 39 LEU L N 1 ATOM 6922 C CA . LEU E 3 59 ? 98.647 -15.486 11.901 1.00 67.77 ? 39 LEU L CA 1 ATOM 6923 C C . LEU E 3 59 ? 99.221 -16.151 13.155 1.00 70.11 ? 39 LEU L C 1 ATOM 6924 O O . LEU E 3 59 ? 99.326 -15.516 14.206 1.00 69.55 ? 39 LEU L O 1 ATOM 6925 C CB . LEU E 3 59 ? 99.641 -14.461 11.331 1.00 67.06 ? 39 LEU L CB 1 ATOM 6926 C CG . LEU E 3 59 ? 99.145 -13.459 10.277 1.00 66.86 ? 39 LEU L CG 1 ATOM 6927 C CD1 . LEU E 3 59 ? 98.319 -12.368 10.966 1.00 69.07 ? 39 LEU L CD1 1 ATOM 6928 C CD2 . LEU E 3 59 ? 100.316 -12.823 9.548 1.00 64.34 ? 39 LEU L CD2 1 ATOM 6929 N N . PRO E 3 60 ? 99.605 -17.436 13.054 1.00 72.59 ? 40 PRO L N 1 ATOM 6930 C CA . PRO E 3 60 ? 100.166 -18.254 14.138 1.00 73.66 ? 40 PRO L CA 1 ATOM 6931 C C . PRO E 3 60 ? 100.750 -17.518 15.355 1.00 74.29 ? 40 PRO L C 1 ATOM 6932 O O . PRO E 3 60 ? 101.673 -16.703 15.228 1.00 73.25 ? 40 PRO L O 1 ATOM 6933 C CB . PRO E 3 60 ? 101.197 -19.105 13.409 1.00 73.66 ? 40 PRO L CB 1 ATOM 6934 C CG . PRO E 3 60 ? 100.479 -19.413 12.135 1.00 73.48 ? 40 PRO L CG 1 ATOM 6935 C CD . PRO E 3 60 ? 99.900 -18.057 11.746 1.00 73.39 ? 40 PRO L CD 1 ATOM 6936 N N . GLY E 3 61 ? 100.195 -17.829 16.530 1.00 74.52 ? 41 GLY L N 1 ATOM 6937 C CA . GLY E 3 61 ? 100.641 -17.222 17.775 1.00 73.91 ? 41 GLY L CA 1 ATOM 6938 C C . GLY E 3 61 ? 100.633 -15.708 17.736 1.00 73.60 ? 41 GLY L C 1 ATOM 6939 O O . GLY E 3 61 ? 101.677 -15.059 17.839 1.00 71.99 ? 41 GLY L O 1 ATOM 6940 N N . THR E 3 62 ? 99.440 -15.146 17.593 1.00 74.17 ? 42 THR L N 1 ATOM 6941 C CA . THR E 3 62 ? 99.271 -13.702 17.520 1.00 74.18 ? 42 THR L CA 1 ATOM 6942 C C . THR E 3 62 ? 97.857 -13.323 17.911 1.00 73.88 ? 42 THR L C 1 ATOM 6943 O O . THR E 3 62 ? 96.930 -14.136 17.822 1.00 74.41 ? 42 THR L O 1 ATOM 6944 C CB . THR E 3 62 ? 99.496 -13.183 16.090 1.00 73.99 ? 42 THR L CB 1 ATOM 6945 O OG1 . THR E 3 62 ? 100.824 -13.499 15.675 1.00 76.01 ? 42 THR L OG1 1 ATOM 6946 C CG2 . THR E 3 62 ? 99.299 -11.680 16.024 1.00 75.37 ? 42 THR L CG2 1 ATOM 6947 N N . ALA E 3 63 ? 97.696 -12.083 18.352 1.00 72.60 ? 43 ALA L N 1 ATOM 6948 C CA . ALA E 3 63 ? 96.382 -11.596 18.711 1.00 69.72 ? 43 ALA L CA 1 ATOM 6949 C C . ALA E 3 63 ? 95.649 -11.455 17.380 1.00 67.49 ? 43 ALA L C 1 ATOM 6950 O O . ALA E 3 63 ? 96.230 -10.996 16.386 1.00 66.66 ? 43 ALA L O 1 ATOM 6951 C CB . ALA E 3 63 ? 96.496 -10.251 19.407 1.00 70.74 ? 43 ALA L CB 1 ATOM 6952 N N . PRO E 3 64 ? 94.375 -11.874 17.333 1.00 64.23 ? 44 PRO L N 1 ATOM 6953 C CA . PRO E 3 64 ? 93.580 -11.786 16.110 1.00 61.12 ? 44 PRO L CA 1 ATOM 6954 C C . PRO E 3 64 ? 93.600 -10.366 15.571 1.00 59.21 ? 44 PRO L C 1 ATOM 6955 O O . PRO E 3 64 ? 93.710 -9.404 16.331 1.00 56.84 ? 44 PRO L O 1 ATOM 6956 C CB . PRO E 3 64 ? 92.195 -12.208 16.579 1.00 61.85 ? 44 PRO L CB 1 ATOM 6957 C CG . PRO E 3 64 ? 92.491 -13.177 17.669 1.00 61.81 ? 44 PRO L CG 1 ATOM 6958 C CD . PRO E 3 64 ? 93.592 -12.484 18.421 1.00 63.46 ? 44 PRO L CD 1 ATOM 6959 N N . LYS E 3 65 ? 93.501 -10.235 14.255 1.00 58.94 ? 45 LYS L N 1 ATOM 6960 C CA . LYS E 3 65 ? 93.505 -8.916 13.626 1.00 59.39 ? 45 LYS L CA 1 ATOM 6961 C C . LYS E 3 65 ? 92.163 -8.677 12.926 1.00 58.31 ? 45 LYS L C 1 ATOM 6962 O O . LYS E 3 65 ? 91.645 -9.561 12.237 1.00 57.68 ? 45 LYS L O 1 ATOM 6963 C CB . LYS E 3 65 ? 94.652 -8.811 12.603 1.00 59.88 ? 45 LYS L CB 1 ATOM 6964 C CG . LYS E 3 65 ? 94.949 -7.388 12.143 1.00 60.17 ? 45 LYS L CG 1 ATOM 6965 C CD . LYS E 3 65 ? 95.785 -7.350 10.864 1.00 61.54 ? 45 LYS L CD 1 ATOM 6966 C CE . LYS E 3 65 ? 96.031 -5.899 10.417 1.00 64.28 ? 45 LYS L CE 1 ATOM 6967 N NZ . LYS E 3 65 ? 96.728 -5.738 9.094 1.00 64.21 ? 45 LYS L NZ 1 ATOM 6968 N N . LEU E 3 66 ? 91.590 -7.493 13.116 1.00 56.18 ? 46 LEU L N 1 ATOM 6969 C CA . LEU E 3 66 ? 90.329 -7.199 12.463 1.00 55.44 ? 46 LEU L CA 1 ATOM 6970 C C . LEU E 3 66 ? 90.624 -7.152 10.976 1.00 54.59 ? 46 LEU L C 1 ATOM 6971 O O . LEU E 3 66 ? 91.556 -6.481 10.548 1.00 54.65 ? 46 LEU L O 1 ATOM 6972 C CB . LEU E 3 66 ? 89.768 -5.856 12.931 1.00 54.76 ? 46 LEU L CB 1 ATOM 6973 C CG . LEU E 3 66 ? 88.553 -5.342 12.150 1.00 52.08 ? 46 LEU L CG 1 ATOM 6974 C CD1 . LEU E 3 66 ? 87.415 -6.357 12.209 1.00 50.07 ? 46 LEU L CD1 1 ATOM 6975 C CD2 . LEU E 3 66 ? 88.126 -4.008 12.723 1.00 49.64 ? 46 LEU L CD2 1 ATOM 6976 N N . LEU E 3 67 ? 89.829 -7.873 10.197 1.00 54.43 ? 47 LEU L N 1 ATOM 6977 C CA . LEU E 3 67 ? 90.020 -7.939 8.753 1.00 54.56 ? 47 LEU L CA 1 ATOM 6978 C C . LEU E 3 67 ? 88.887 -7.244 7.998 1.00 55.32 ? 47 LEU L C 1 ATOM 6979 O O . LEU E 3 67 ? 89.119 -6.508 7.033 1.00 55.44 ? 47 LEU L O 1 ATOM 6980 C CB . LEU E 3 67 ? 90.110 -9.402 8.326 1.00 53.05 ? 47 LEU L CB 1 ATOM 6981 C CG . LEU E 3 67 ? 90.728 -9.653 6.962 1.00 52.33 ? 47 LEU L CG 1 ATOM 6982 C CD1 . LEU E 3 67 ? 92.030 -8.877 6.865 1.00 51.04 ? 47 LEU L CD1 1 ATOM 6983 C CD2 . LEU E 3 67 ? 90.954 -11.148 6.764 1.00 51.21 ? 47 LEU L CD2 1 ATOM 6984 N N . ILE E 3 68 ? 87.660 -7.477 8.449 1.00 55.20 ? 48 ILE L N 1 ATOM 6985 C CA . ILE E 3 68 ? 86.495 -6.872 7.829 1.00 53.56 ? 48 ILE L CA 1 ATOM 6986 C C . ILE E 3 68 ? 85.400 -6.620 8.843 1.00 52.04 ? 48 ILE L C 1 ATOM 6987 O O . ILE E 3 68 ? 85.093 -7.485 9.667 1.00 51.24 ? 48 ILE L O 1 ATOM 6988 C CB . ILE E 3 68 ? 85.951 -7.769 6.708 1.00 54.73 ? 48 ILE L CB 1 ATOM 6989 C CG1 . ILE E 3 68 ? 86.826 -7.594 5.473 1.00 57.23 ? 48 ILE L CG1 1 ATOM 6990 C CG2 . ILE E 3 68 ? 84.500 -7.440 6.404 1.00 53.58 ? 48 ILE L CG2 1 ATOM 6991 C CD1 . ILE E 3 68 ? 86.350 -8.363 4.277 1.00 60.75 ? 48 ILE L CD1 1 ATOM 6992 N N . TYR E 3 69 ? 84.824 -5.424 8.787 1.00 50.23 ? 49 TYR L N 1 ATOM 6993 C CA . TYR E 3 69 ? 83.736 -5.077 9.687 1.00 49.94 ? 49 TYR L CA 1 ATOM 6994 C C . TYR E 3 69 ? 82.481 -4.704 8.900 1.00 50.25 ? 49 TYR L C 1 ATOM 6995 O O . TYR E 3 69 ? 82.564 -4.294 7.736 1.00 50.47 ? 49 TYR L O 1 ATOM 6996 C CB . TYR E 3 69 ? 84.152 -3.942 10.618 1.00 46.87 ? 49 TYR L CB 1 ATOM 6997 C CG . TYR E 3 69 ? 84.403 -2.637 9.947 1.00 45.66 ? 49 TYR L CG 1 ATOM 6998 C CD1 . TYR E 3 69 ? 83.447 -1.631 9.978 1.00 44.88 ? 49 TYR L CD1 1 ATOM 6999 C CD2 . TYR E 3 69 ? 85.614 -2.388 9.303 1.00 46.27 ? 49 TYR L CD2 1 ATOM 7000 C CE1 . TYR E 3 69 ? 83.688 -0.402 9.392 1.00 46.37 ? 49 TYR L CE1 1 ATOM 7001 C CE2 . TYR E 3 69 ? 85.870 -1.164 8.707 1.00 46.14 ? 49 TYR L CE2 1 ATOM 7002 C CZ . TYR E 3 69 ? 84.902 -0.174 8.758 1.00 46.85 ? 49 TYR L CZ 1 ATOM 7003 O OH . TYR E 3 69 ? 85.146 1.046 8.181 1.00 48.52 ? 49 TYR L OH 1 ATOM 7004 N N . ARG E 3 70 ? 81.324 -4.856 9.543 1.00 49.46 ? 50 ARG L N 1 ATOM 7005 C CA . ARG E 3 70 ? 80.031 -4.569 8.921 1.00 48.04 ? 50 ARG L CA 1 ATOM 7006 C C . ARG E 3 70 ? 79.859 -5.258 7.557 1.00 46.87 ? 50 ARG L C 1 ATOM 7007 O O . ARG E 3 70 ? 79.582 -4.631 6.538 1.00 45.46 ? 50 ARG L O 1 ATOM 7008 C CB . ARG E 3 70 ? 79.799 -3.053 8.812 1.00 46.29 ? 50 ARG L CB 1 ATOM 7009 C CG . ARG E 3 70 ? 79.488 -2.421 10.160 1.00 45.97 ? 50 ARG L CG 1 ATOM 7010 C CD . ARG E 3 70 ? 78.765 -1.078 10.059 1.00 46.11 ? 50 ARG L CD 1 ATOM 7011 N NE . ARG E 3 70 ? 79.662 0.074 9.992 1.00 44.80 ? 50 ARG L NE 1 ATOM 7012 C CZ . ARG E 3 70 ? 80.019 0.687 8.868 1.00 46.68 ? 50 ARG L CZ 1 ATOM 7013 N NH1 . ARG E 3 70 ? 79.553 0.266 7.698 1.00 47.10 ? 50 ARG L NH1 1 ATOM 7014 N NH2 . ARG E 3 70 ? 80.849 1.721 8.914 1.00 47.77 ? 50 ARG L NH2 1 ATOM 7015 N N . ASN E 3 71 ? 80.041 -6.571 7.566 1.00 45.89 ? 51 ASN L N 1 ATOM 7016 C CA . ASN E 3 71 ? 79.882 -7.380 6.383 1.00 45.99 ? 51 ASN L CA 1 ATOM 7017 C C . ASN E 3 71 ? 80.983 -7.273 5.358 1.00 46.93 ? 51 ASN L C 1 ATOM 7018 O O . ASN E 3 71 ? 81.493 -8.291 4.904 1.00 47.10 ? 51 ASN L O 1 ATOM 7019 C CB . ASN E 3 71 ? 78.569 -7.057 5.679 1.00 47.52 ? 51 ASN L CB 1 ATOM 7020 C CG . ASN E 3 71 ? 77.383 -7.113 6.599 1.00 49.90 ? 51 ASN L CG 1 ATOM 7021 O OD1 . ASN E 3 71 ? 77.282 -7.986 7.463 1.00 50.96 ? 51 ASN L OD1 1 ATOM 7022 N ND2 . ASN E 3 71 ? 76.459 -6.183 6.409 1.00 49.89 ? 51 ASN L ND2 1 ATOM 7023 N N . ASN E 3 72 ? 81.359 -6.055 4.982 1.00 48.33 ? 52 ASN L N 1 ATOM 7024 C CA . ASN E 3 72 ? 82.372 -5.904 3.940 1.00 48.70 ? 52 ASN L CA 1 ATOM 7025 C C . ASN E 3 72 ? 83.211 -4.647 3.963 1.00 49.67 ? 52 ASN L C 1 ATOM 7026 O O . ASN E 3 72 ? 83.644 -4.186 2.911 1.00 48.73 ? 52 ASN L O 1 ATOM 7027 C CB . ASN E 3 72 ? 81.693 -5.950 2.588 1.00 48.30 ? 52 ASN L CB 1 ATOM 7028 C CG . ASN E 3 72 ? 80.613 -4.896 2.465 1.00 47.09 ? 52 ASN L CG 1 ATOM 7029 O OD1 . ASN E 3 72 ? 80.801 -3.757 2.881 1.00 44.85 ? 52 ASN L OD1 1 ATOM 7030 N ND2 . ASN E 3 72 ? 79.476 -5.272 1.892 1.00 48.16 ? 52 ASN L ND2 1 ATOM 7031 N N . GLN E 3 73 ? 83.437 -4.068 5.130 1.00 51.20 ? 53 GLN L N 1 ATOM 7032 C CA . GLN E 3 73 ? 84.256 -2.875 5.167 1.00 52.75 ? 53 GLN L CA 1 ATOM 7033 C C . GLN E 3 73 ? 85.670 -3.277 5.552 1.00 54.36 ? 53 GLN L C 1 ATOM 7034 O O . GLN E 3 73 ? 85.867 -4.088 6.457 1.00 54.90 ? 53 GLN L O 1 ATOM 7035 C CB . GLN E 3 73 ? 83.687 -1.879 6.167 1.00 53.08 ? 53 GLN L CB 1 ATOM 7036 C CG . GLN E 3 73 ? 82.239 -1.504 5.902 1.00 53.52 ? 53 GLN L CG 1 ATOM 7037 C CD . GLN E 3 73 ? 82.015 -0.928 4.517 1.00 53.74 ? 53 GLN L CD 1 ATOM 7038 O OE1 . GLN E 3 73 ? 82.585 0.099 4.155 1.00 54.09 ? 53 GLN L OE1 1 ATOM 7039 N NE2 . GLN E 3 73 ? 81.173 -1.589 3.736 1.00 53.45 ? 53 GLN L NE2 1 ATOM 7040 N N . ARG E 3 74 ? 86.646 -2.727 4.838 1.00 56.32 ? 54 ARG L N 1 ATOM 7041 C CA . ARG E 3 74 ? 88.054 -3.009 5.093 1.00 58.84 ? 54 ARG L CA 1 ATOM 7042 C C . ARG E 3 74 ? 88.695 -1.858 5.859 1.00 60.04 ? 54 ARG L C 1 ATOM 7043 O O . ARG E 3 74 ? 88.820 -0.745 5.347 1.00 59.83 ? 54 ARG L O 1 ATOM 7044 C CB . ARG E 3 74 ? 88.808 -3.201 3.781 1.00 59.78 ? 54 ARG L CB 1 ATOM 7045 C CG . ARG E 3 74 ? 88.561 -4.518 3.074 1.00 64.44 ? 54 ARG L CG 1 ATOM 7046 C CD . ARG E 3 74 ? 88.821 -4.414 1.563 1.00 68.21 ? 54 ARG L CD 1 ATOM 7047 N NE . ARG E 3 74 ? 90.089 -3.760 1.228 1.00 73.56 ? 54 ARG L NE 1 ATOM 7048 C CZ . ARG E 3 74 ? 90.300 -2.441 1.264 1.00 75.66 ? 54 ARG L CZ 1 ATOM 7049 N NH1 . ARG E 3 74 ? 89.326 -1.614 1.621 1.00 75.89 ? 54 ARG L NH1 1 ATOM 7050 N NH2 . ARG E 3 74 ? 91.489 -1.943 0.941 1.00 76.47 ? 54 ARG L NH2 1 ATOM 7051 N N . PRO E 3 75 ? 89.123 -2.112 7.098 1.00 61.19 ? 55 PRO L N 1 ATOM 7052 C CA . PRO E 3 75 ? 89.744 -1.031 7.859 1.00 63.74 ? 55 PRO L CA 1 ATOM 7053 C C . PRO E 3 75 ? 91.073 -0.633 7.216 1.00 66.76 ? 55 PRO L C 1 ATOM 7054 O O . PRO E 3 75 ? 91.957 -1.472 7.031 1.00 67.59 ? 55 PRO L O 1 ATOM 7055 C CB . PRO E 3 75 ? 89.904 -1.646 9.242 1.00 61.41 ? 55 PRO L CB 1 ATOM 7056 C CG . PRO E 3 75 ? 90.165 -3.068 8.930 1.00 60.57 ? 55 PRO L CG 1 ATOM 7057 C CD . PRO E 3 75 ? 89.194 -3.386 7.830 1.00 60.33 ? 55 PRO L CD 1 ATOM 7058 N N . SER E 3 76 ? 91.194 0.643 6.854 1.00 70.19 ? 56 SER L N 1 ATOM 7059 C CA . SER E 3 76 ? 92.410 1.170 6.227 1.00 72.83 ? 56 SER L CA 1 ATOM 7060 C C . SER E 3 76 ? 93.670 0.517 6.767 1.00 72.41 ? 56 SER L C 1 ATOM 7061 O O . SER E 3 76 ? 94.098 0.797 7.884 1.00 71.96 ? 56 SER L O 1 ATOM 7062 C CB . SER E 3 76 ? 92.513 2.680 6.441 1.00 75.47 ? 56 SER L CB 1 ATOM 7063 O OG . SER E 3 76 ? 93.833 3.131 6.168 1.00 79.75 ? 56 SER L OG 1 ATOM 7064 N N . GLY E 3 77 ? 94.272 -0.337 5.951 1.00 72.77 ? 57 GLY L N 1 ATOM 7065 C CA . GLY E 3 77 ? 95.465 -1.039 6.366 1.00 73.42 ? 57 GLY L CA 1 ATOM 7066 C C . GLY E 3 77 ? 95.264 -2.505 6.058 1.00 74.04 ? 57 GLY L C 1 ATOM 7067 O O . GLY E 3 77 ? 96.028 -3.361 6.504 1.00 75.20 ? 57 GLY L O 1 ATOM 7068 N N . VAL E 3 78 ? 94.207 -2.788 5.304 1.00 74.32 ? 58 VAL L N 1 ATOM 7069 C CA . VAL E 3 78 ? 93.882 -4.145 4.892 1.00 73.77 ? 58 VAL L CA 1 ATOM 7070 C C . VAL E 3 78 ? 93.806 -4.155 3.367 1.00 74.57 ? 58 VAL L C 1 ATOM 7071 O O . VAL E 3 78 ? 93.207 -3.263 2.764 1.00 74.21 ? 58 VAL L O 1 ATOM 7072 C CB . VAL E 3 78 ? 92.536 -4.606 5.475 1.00 73.20 ? 58 VAL L CB 1 ATOM 7073 C CG1 . VAL E 3 78 ? 92.198 -5.986 4.948 1.00 73.21 ? 58 VAL L CG1 1 ATOM 7074 C CG2 . VAL E 3 78 ? 92.606 -4.632 6.992 1.00 71.56 ? 58 VAL L CG2 1 ATOM 7075 N N . PRO E 3 79 ? 94.422 -5.163 2.727 1.00 75.08 ? 59 PRO L N 1 ATOM 7076 C CA . PRO E 3 79 ? 94.474 -5.353 1.270 1.00 75.32 ? 59 PRO L CA 1 ATOM 7077 C C . PRO E 3 79 ? 93.125 -5.430 0.545 1.00 75.87 ? 59 PRO L C 1 ATOM 7078 O O . PRO E 3 79 ? 92.153 -6.000 1.052 1.00 75.20 ? 59 PRO L O 1 ATOM 7079 C CB . PRO E 3 79 ? 95.264 -6.651 1.120 1.00 74.32 ? 59 PRO L CB 1 ATOM 7080 C CG . PRO E 3 79 ? 96.122 -6.668 2.329 1.00 74.94 ? 59 PRO L CG 1 ATOM 7081 C CD . PRO E 3 79 ? 95.182 -6.224 3.408 1.00 74.67 ? 59 PRO L CD 1 ATOM 7082 N N . ASP E 3 80 ? 93.091 -4.866 -0.658 1.00 75.60 ? 60 ASP L N 1 ATOM 7083 C CA . ASP E 3 80 ? 91.892 -4.869 -1.483 1.00 76.05 ? 60 ASP L CA 1 ATOM 7084 C C . ASP E 3 80 ? 91.533 -6.307 -1.827 1.00 75.46 ? 60 ASP L C 1 ATOM 7085 O O . ASP E 3 80 ? 90.394 -6.612 -2.180 1.00 76.64 ? 60 ASP L O 1 ATOM 7086 C CB . ASP E 3 80 ? 92.149 -4.098 -2.771 1.00 78.12 ? 60 ASP L CB 1 ATOM 7087 C CG . ASP E 3 80 ? 92.810 -2.762 -2.523 1.00 81.05 ? 60 ASP L CG 1 ATOM 7088 O OD1 . ASP E 3 80 ? 92.149 -1.865 -1.952 1.00 82.04 ? 60 ASP L OD1 1 ATOM 7089 O OD2 . ASP E 3 80 ? 93.998 -2.613 -2.893 1.00 83.21 ? 60 ASP L OD2 1 ATOM 7090 N N . ARG E 3 81 ? 92.518 -7.190 -1.731 1.00 73.91 ? 61 ARG L N 1 ATOM 7091 C CA . ARG E 3 81 ? 92.311 -8.598 -2.037 1.00 72.44 ? 61 ARG L CA 1 ATOM 7092 C C . ARG E 3 81 ? 91.343 -9.226 -1.052 1.00 71.21 ? 61 ARG L C 1 ATOM 7093 O O . ARG E 3 81 ? 90.734 -10.265 -1.343 1.00 72.08 ? 61 ARG L O 1 ATOM 7094 C CB . ARG E 3 81 ? 93.634 -9.346 -1.973 1.00 73.46 ? 61 ARG L CB 1 ATOM 7095 C CG . ARG E 3 81 ? 94.706 -8.799 -2.888 1.00 73.10 ? 61 ARG L CG 1 ATOM 7096 C CD . ARG E 3 81 ? 95.991 -8.658 -2.108 1.00 73.26 ? 61 ARG L CD 1 ATOM 7097 N NE . ARG E 3 81 ? 96.161 -9.763 -1.166 1.00 72.26 ? 61 ARG L NE 1 ATOM 7098 C CZ . ARG E 3 81 ? 97.148 -9.840 -0.282 1.00 70.87 ? 61 ARG L CZ 1 ATOM 7099 N NH1 . ARG E 3 81 ? 98.061 -8.873 -0.221 1.00 68.49 ? 61 ARG L NH1 1 ATOM 7100 N NH2 . ARG E 3 81 ? 97.214 -10.878 0.541 1.00 69.75 ? 61 ARG L NH2 1 ATOM 7101 N N . PHE E 3 82 ? 91.217 -8.603 0.119 1.00 67.47 ? 62 PHE L N 1 ATOM 7102 C CA . PHE E 3 82 ? 90.318 -9.103 1.148 1.00 64.04 ? 62 PHE L CA 1 ATOM 7103 C C . PHE E 3 82 ? 88.947 -8.458 0.997 1.00 61.61 ? 62 PHE L C 1 ATOM 7104 O O . PHE E 3 82 ? 88.820 -7.235 0.999 1.00 60.06 ? 62 PHE L O 1 ATOM 7105 C CB . PHE E 3 82 ? 90.891 -8.817 2.539 1.00 64.35 ? 62 PHE L CB 1 ATOM 7106 C CG . PHE E 3 82 ? 92.144 -9.599 2.857 1.00 65.67 ? 62 PHE L CG 1 ATOM 7107 C CD1 . PHE E 3 82 ? 92.113 -10.989 2.962 1.00 64.87 ? 62 PHE L CD1 1 ATOM 7108 C CD2 . PHE E 3 82 ? 93.361 -8.944 3.051 1.00 66.11 ? 62 PHE L CD2 1 ATOM 7109 C CE1 . PHE E 3 82 ? 93.273 -11.710 3.253 1.00 63.25 ? 62 PHE L CE1 1 ATOM 7110 C CE2 . PHE E 3 82 ? 94.522 -9.661 3.343 1.00 63.93 ? 62 PHE L CE2 1 ATOM 7111 C CZ . PHE E 3 82 ? 94.474 -11.045 3.442 1.00 63.30 ? 62 PHE L CZ 1 ATOM 7112 N N . SER E 3 83 ? 87.921 -9.292 0.856 1.00 60.05 ? 63 SER L N 1 ATOM 7113 C CA . SER E 3 83 ? 86.558 -8.794 0.699 1.00 57.92 ? 63 SER L CA 1 ATOM 7114 C C . SER E 3 83 ? 85.573 -9.623 1.498 1.00 56.54 ? 63 SER L C 1 ATOM 7115 O O . SER E 3 83 ? 85.731 -10.838 1.630 1.00 56.41 ? 63 SER L O 1 ATOM 7116 C CB . SER E 3 83 ? 86.135 -8.848 -0.766 1.00 58.51 ? 63 SER L CB 1 ATOM 7117 O OG . SER E 3 83 ? 85.752 -10.168 -1.125 1.00 56.48 ? 63 SER L OG 1 ATOM 7118 N N . GLY E 3 84 ? 84.547 -8.960 2.018 1.00 55.01 ? 64 GLY L N 1 ATOM 7119 C CA . GLY E 3 84 ? 83.529 -9.663 2.774 1.00 53.14 ? 64 GLY L CA 1 ATOM 7120 C C . GLY E 3 84 ? 82.168 -9.521 2.118 1.00 52.16 ? 64 GLY L C 1 ATOM 7121 O O . GLY E 3 84 ? 81.948 -8.627 1.294 1.00 52.01 ? 64 GLY L O 1 ATOM 7122 N N . SER E 3 85 ? 81.244 -10.403 2.475 1.00 51.69 ? 65 SER L N 1 ATOM 7123 C CA . SER E 3 85 ? 79.904 -10.345 1.906 1.00 51.11 ? 65 SER L CA 1 ATOM 7124 C C . SER E 3 85 ? 78.956 -11.230 2.679 1.00 51.63 ? 65 SER L C 1 ATOM 7125 O O . SER E 3 85 ? 79.352 -12.232 3.277 1.00 51.78 ? 65 SER L O 1 ATOM 7126 C CB . SER E 3 85 ? 79.904 -10.829 0.469 1.00 50.18 ? 65 SER L CB 1 ATOM 7127 O OG . SER E 3 85 ? 79.822 -12.243 0.454 1.00 48.99 ? 65 SER L OG 1 ATOM 7128 N N . LYS E 3 86 ? 77.688 -10.860 2.641 1.00 52.31 ? 66 LYS L N 1 ATOM 7129 C CA . LYS E 3 86 ? 76.665 -11.614 3.327 1.00 52.80 ? 66 LYS L CA 1 ATOM 7130 C C . LYS E 3 86 ? 75.489 -11.728 2.380 1.00 54.65 ? 66 LYS L C 1 ATOM 7131 O O . LYS E 3 86 ? 75.376 -10.966 1.425 1.00 55.60 ? 66 LYS L O 1 ATOM 7132 C CB . LYS E 3 86 ? 76.255 -10.882 4.601 1.00 50.62 ? 66 LYS L CB 1 ATOM 7133 C CG . LYS E 3 86 ? 75.101 -11.508 5.339 1.00 49.30 ? 66 LYS L CG 1 ATOM 7134 C CD . LYS E 3 86 ? 74.813 -10.720 6.600 1.00 48.78 ? 66 LYS L CD 1 ATOM 7135 C CE . LYS E 3 86 ? 73.421 -10.998 7.131 1.00 47.29 ? 66 LYS L CE 1 ATOM 7136 N NZ . LYS E 3 86 ? 73.259 -10.489 8.517 1.00 45.66 ? 66 LYS L NZ 1 ATOM 7137 N N . SER E 3 87 ? 74.623 -12.692 2.644 1.00 56.33 ? 67 SER L N 1 ATOM 7138 C CA . SER E 3 87 ? 73.439 -12.914 1.833 1.00 57.05 ? 67 SER L CA 1 ATOM 7139 C C . SER E 3 87 ? 72.729 -14.049 2.545 1.00 56.50 ? 67 SER L C 1 ATOM 7140 O O . SER E 3 87 ? 73.340 -15.073 2.844 1.00 56.07 ? 67 SER L O 1 ATOM 7141 C CB . SER E 3 87 ? 73.838 -13.330 0.413 1.00 59.86 ? 67 SER L CB 1 ATOM 7142 O OG . SER E 3 87 ? 72.713 -13.401 -0.451 1.00 63.33 ? 67 SER L OG 1 ATOM 7143 N N . GLY E 3 88 ? 71.447 -13.859 2.833 1.00 57.09 ? 68 GLY L N 1 ATOM 7144 C CA . GLY E 3 88 ? 70.695 -14.881 3.539 1.00 55.32 ? 68 GLY L CA 1 ATOM 7145 C C . GLY E 3 88 ? 71.251 -14.959 4.944 1.00 54.11 ? 68 GLY L C 1 ATOM 7146 O O . GLY E 3 88 ? 71.510 -13.931 5.566 1.00 53.84 ? 68 GLY L O 1 ATOM 7147 N N . THR E 3 89 ? 71.443 -16.168 5.451 1.00 53.17 ? 69 THR L N 1 ATOM 7148 C CA . THR E 3 89 ? 71.992 -16.321 6.783 1.00 53.55 ? 69 THR L CA 1 ATOM 7149 C C . THR E 3 89 ? 73.430 -16.789 6.704 1.00 53.84 ? 69 THR L C 1 ATOM 7150 O O . THR E 3 89 ? 73.879 -17.595 7.520 1.00 54.49 ? 69 THR L O 1 ATOM 7151 C CB . THR E 3 89 ? 71.187 -17.320 7.628 1.00 53.24 ? 69 THR L CB 1 ATOM 7152 O OG1 . THR E 3 89 ? 70.678 -18.360 6.788 1.00 52.83 ? 69 THR L OG1 1 ATOM 7153 C CG2 . THR E 3 89 ? 70.048 -16.612 8.337 1.00 54.00 ? 69 THR L CG2 1 ATOM 7154 N N . SER E 3 90 ? 74.158 -16.280 5.720 1.00 53.29 ? 70 SER L N 1 ATOM 7155 C CA . SER E 3 90 ? 75.546 -16.662 5.572 1.00 53.41 ? 70 SER L CA 1 ATOM 7156 C C . SER E 3 90 ? 76.407 -15.560 5.014 1.00 52.54 ? 70 SER L C 1 ATOM 7157 O O . SER E 3 90 ? 75.923 -14.625 4.377 1.00 53.90 ? 70 SER L O 1 ATOM 7158 C CB . SER E 3 90 ? 75.656 -17.897 4.695 1.00 55.54 ? 70 SER L CB 1 ATOM 7159 O OG . SER E 3 90 ? 75.033 -19.005 5.328 1.00 60.85 ? 70 SER L OG 1 ATOM 7160 N N . ALA E 3 91 ? 77.697 -15.672 5.276 1.00 50.68 ? 71 ALA L N 1 ATOM 7161 C CA . ALA E 3 91 ? 78.650 -14.693 4.808 1.00 50.56 ? 71 ALA L CA 1 ATOM 7162 C C . ALA E 3 91 ? 79.892 -15.435 4.381 1.00 51.79 ? 71 ALA L C 1 ATOM 7163 O O . ALA E 3 91 ? 80.060 -16.626 4.675 1.00 50.27 ? 71 ALA L O 1 ATOM 7164 C CB . ALA E 3 91 ? 78.989 -13.721 5.913 1.00 50.63 ? 71 ALA L CB 1 ATOM 7165 N N . SER E 3 92 ? 80.770 -14.725 3.690 1.00 52.53 ? 72 SER L N 1 ATOM 7166 C CA . SER E 3 92 ? 81.993 -15.332 3.232 1.00 54.04 ? 72 SER L CA 1 ATOM 7167 C C . SER E 3 92 ? 83.051 -14.292 2.958 1.00 54.05 ? 72 SER L C 1 ATOM 7168 O O . SER E 3 92 ? 82.762 -13.186 2.504 1.00 53.66 ? 72 SER L O 1 ATOM 7169 C CB . SER E 3 92 ? 81.731 -16.162 1.979 1.00 55.37 ? 72 SER L CB 1 ATOM 7170 O OG . SER E 3 92 ? 81.158 -15.352 0.974 1.00 59.83 ? 72 SER L OG 1 ATOM 7171 N N . LEU E 3 93 ? 84.283 -14.680 3.262 1.00 54.74 ? 73 LEU L N 1 ATOM 7172 C CA . LEU E 3 93 ? 85.463 -13.857 3.086 1.00 54.13 ? 73 LEU L CA 1 ATOM 7173 C C . LEU E 3 93 ? 86.112 -14.370 1.812 1.00 54.03 ? 73 LEU L C 1 ATOM 7174 O O . LEU E 3 93 ? 86.065 -15.566 1.535 1.00 54.14 ? 73 LEU L O 1 ATOM 7175 C CB . LEU E 3 93 ? 86.390 -14.079 4.285 1.00 54.32 ? 73 LEU L CB 1 ATOM 7176 C CG . LEU E 3 93 ? 87.634 -13.213 4.479 1.00 54.77 ? 73 LEU L CG 1 ATOM 7177 C CD1 . LEU E 3 93 ? 87.231 -11.811 4.935 1.00 53.29 ? 73 LEU L CD1 1 ATOM 7178 C CD2 . LEU E 3 93 ? 88.538 -13.874 5.513 1.00 52.91 ? 73 LEU L CD2 1 ATOM 7179 N N . ALA E 3 94 ? 86.705 -13.485 1.027 1.00 55.52 ? 74 ALA L N 1 ATOM 7180 C CA . ALA E 3 94 ? 87.353 -13.922 -0.200 1.00 58.45 ? 74 ALA L CA 1 ATOM 7181 C C . ALA E 3 94 ? 88.708 -13.268 -0.385 1.00 62.01 ? 74 ALA L C 1 ATOM 7182 O O . ALA E 3 94 ? 88.821 -12.035 -0.404 1.00 61.81 ? 74 ALA L O 1 ATOM 7183 C CB . ALA E 3 94 ? 86.473 -13.627 -1.393 1.00 57.51 ? 74 ALA L CB 1 ATOM 7184 N N . ILE E 3 95 ? 89.735 -14.107 -0.513 1.00 66.00 ? 75 ILE L N 1 ATOM 7185 C CA . ILE E 3 95 ? 91.106 -13.631 -0.712 1.00 69.31 ? 75 ILE L CA 1 ATOM 7186 C C . ILE E 3 95 ? 91.472 -13.797 -2.189 1.00 70.94 ? 75 ILE L C 1 ATOM 7187 O O . ILE E 3 95 ? 91.260 -14.862 -2.773 1.00 71.19 ? 75 ILE L O 1 ATOM 7188 C CB . ILE E 3 95 ? 92.158 -14.452 0.098 1.00 69.25 ? 75 ILE L CB 1 ATOM 7189 C CG1 . ILE E 3 95 ? 91.534 -15.084 1.348 1.00 69.01 ? 75 ILE L CG1 1 ATOM 7190 C CG2 . ILE E 3 95 ? 93.319 -13.543 0.483 1.00 69.43 ? 75 ILE L CG2 1 ATOM 7191 C CD1 . ILE E 3 95 ? 91.427 -14.173 2.551 1.00 68.28 ? 75 ILE L CD1 1 ATOM 7192 N N . SER E 3 96 ? 92.016 -12.746 -2.788 1.00 72.35 ? 76 SER L N 1 ATOM 7193 C CA . SER E 3 96 ? 92.427 -12.801 -4.181 1.00 74.87 ? 76 SER L CA 1 ATOM 7194 C C . SER E 3 96 ? 93.914 -12.485 -4.238 1.00 76.83 ? 76 SER L C 1 ATOM 7195 O O . SER E 3 96 ? 94.420 -11.734 -3.404 1.00 77.34 ? 76 SER L O 1 ATOM 7196 C CB . SER E 3 96 ? 91.648 -11.781 -5.003 1.00 75.16 ? 76 SER L CB 1 ATOM 7197 O OG . SER E 3 96 ? 90.267 -12.084 -4.986 1.00 77.17 ? 76 SER L OG 1 ATOM 7198 N N . GLY E 3 97 ? 94.614 -13.054 -5.214 1.00 78.44 ? 77 GLY L N 1 ATOM 7199 C CA . GLY E 3 97 ? 96.043 -12.802 -5.325 1.00 80.06 ? 77 GLY L CA 1 ATOM 7200 C C . GLY E 3 97 ? 96.760 -13.343 -4.101 1.00 80.96 ? 77 GLY L C 1 ATOM 7201 O O . GLY E 3 97 ? 97.709 -12.731 -3.592 1.00 80.95 ? 77 GLY L O 1 ATOM 7202 N N . LEU E 3 98 ? 96.286 -14.501 -3.638 1.00 80.96 ? 78 LEU L N 1 ATOM 7203 C CA . LEU E 3 98 ? 96.824 -15.191 -2.467 1.00 81.27 ? 78 LEU L CA 1 ATOM 7204 C C . LEU E 3 98 ? 98.347 -15.121 -2.376 1.00 82.40 ? 78 LEU L C 1 ATOM 7205 O O . LEU E 3 98 ? 99.045 -15.090 -3.388 1.00 83.75 ? 78 LEU L O 1 ATOM 7206 C CB . LEU E 3 98 ? 96.389 -16.658 -2.490 1.00 78.53 ? 78 LEU L CB 1 ATOM 7207 C CG . LEU E 3 98 ? 95.782 -17.237 -1.213 1.00 77.66 ? 78 LEU L CG 1 ATOM 7208 C CD1 . LEU E 3 98 ? 95.488 -18.710 -1.436 1.00 78.53 ? 78 LEU L CD1 1 ATOM 7209 C CD2 . LEU E 3 98 ? 96.724 -17.054 -0.042 1.00 77.02 ? 78 LEU L CD2 1 ATOM 7210 N N . ARG E 3 99 ? 98.858 -15.103 -1.154 1.00 82.57 ? 79 ARG L N 1 ATOM 7211 C CA . ARG E 3 99 ? 100.290 -15.048 -0.935 1.00 83.28 ? 79 ARG L CA 1 ATOM 7212 C C . ARG E 3 99 ? 100.616 -16.034 0.183 1.00 84.73 ? 79 ARG L C 1 ATOM 7213 O O . ARG E 3 99 ? 99.739 -16.779 0.624 1.00 84.93 ? 79 ARG L O 1 ATOM 7214 C CB . ARG E 3 99 ? 100.679 -13.616 -0.575 1.00 81.95 ? 79 ARG L CB 1 ATOM 7215 C CG . ARG E 3 99 ? 100.210 -12.627 -1.634 1.00 81.62 ? 79 ARG L CG 1 ATOM 7216 C CD . ARG E 3 99 ? 100.230 -11.171 -1.177 1.00 83.27 ? 79 ARG L CD 1 ATOM 7217 N NE . ARG E 3 99 ? 101.565 -10.579 -1.139 1.00 84.41 ? 79 ARG L NE 1 ATOM 7218 C CZ . ARG E 3 99 ? 102.471 -10.809 -0.194 1.00 85.14 ? 79 ARG L CZ 1 ATOM 7219 N NH1 . ARG E 3 99 ? 103.659 -10.217 -0.262 1.00 85.46 ? 79 ARG L NH1 1 ATOM 7220 N NH2 . ARG E 3 99 ? 102.194 -11.621 0.818 1.00 84.42 ? 79 ARG L NH2 1 ATOM 7221 N N . SER E 3 100 ? 101.866 -16.076 0.630 1.00 85.58 ? 80 SER L N 1 ATOM 7222 C CA . SER E 3 100 ? 102.215 -17.002 1.698 1.00 86.23 ? 80 SER L CA 1 ATOM 7223 C C . SER E 3 100 ? 101.909 -16.333 3.033 1.00 86.33 ? 80 SER L C 1 ATOM 7224 O O . SER E 3 100 ? 101.560 -16.997 4.011 1.00 86.43 ? 80 SER L O 1 ATOM 7225 C CB . SER E 3 100 ? 103.696 -17.394 1.621 1.00 86.98 ? 80 SER L CB 1 ATOM 7226 O OG . SER E 3 100 ? 104.543 -16.310 1.957 1.00 88.11 ? 80 SER L OG 1 ATOM 7227 N N . GLU E 3 101 ? 102.024 -15.009 3.059 1.00 86.23 ? 81 GLU L N 1 ATOM 7228 C CA . GLU E 3 101 ? 101.753 -14.242 4.270 1.00 86.09 ? 81 GLU L CA 1 ATOM 7229 C C . GLU E 3 101 ? 100.248 -14.203 4.538 1.00 83.96 ? 81 GLU L C 1 ATOM 7230 O O . GLU E 3 101 ? 99.748 -13.290 5.192 1.00 83.90 ? 81 GLU L O 1 ATOM 7231 C CB . GLU E 3 101 ? 102.280 -12.807 4.124 1.00 87.96 ? 81 GLU L CB 1 ATOM 7232 C CG . GLU E 3 101 ? 103.686 -12.687 3.539 1.00 90.69 ? 81 GLU L CG 1 ATOM 7233 C CD . GLU E 3 101 ? 104.225 -11.259 3.598 1.00 92.84 ? 81 GLU L CD 1 ATOM 7234 O OE1 . GLU E 3 101 ? 103.463 -10.317 3.276 1.00 93.19 ? 81 GLU L OE1 1 ATOM 7235 O OE2 . GLU E 3 101 ? 105.413 -11.079 3.959 1.00 93.44 ? 81 GLU L OE2 1 ATOM 7236 N N . ASP E 3 102 ? 99.528 -15.194 4.027 1.00 81.97 ? 82 ASP L N 1 ATOM 7237 C CA . ASP E 3 102 ? 98.089 -15.246 4.206 1.00 80.34 ? 82 ASP L CA 1 ATOM 7238 C C . ASP E 3 102 ? 97.624 -16.536 4.830 1.00 80.14 ? 82 ASP L C 1 ATOM 7239 O O . ASP E 3 102 ? 96.446 -16.672 5.139 1.00 81.44 ? 82 ASP L O 1 ATOM 7240 C CB . ASP E 3 102 ? 97.368 -15.043 2.870 1.00 79.22 ? 82 ASP L CB 1 ATOM 7241 C CG . ASP E 3 102 ? 97.296 -13.580 2.458 1.00 79.30 ? 82 ASP L CG 1 ATOM 7242 O OD1 . ASP E 3 102 ? 96.875 -13.306 1.314 1.00 78.31 ? 82 ASP L OD1 1 ATOM 7243 O OD2 . ASP E 3 102 ? 97.652 -12.703 3.279 1.00 79.16 ? 82 ASP L OD2 1 ATOM 7244 N N . GLU E 3 103 ? 98.518 -17.501 5.006 1.00 80.05 ? 83 GLU L N 1 ATOM 7245 C CA . GLU E 3 103 ? 98.076 -18.735 5.638 1.00 80.11 ? 83 GLU L CA 1 ATOM 7246 C C . GLU E 3 103 ? 98.075 -18.489 7.132 1.00 78.59 ? 83 GLU L C 1 ATOM 7247 O O . GLU E 3 103 ? 99.116 -18.322 7.756 1.00 79.08 ? 83 GLU L O 1 ATOM 7248 C CB . GLU E 3 103 ? 98.959 -19.947 5.276 1.00 82.15 ? 83 GLU L CB 1 ATOM 7249 C CG . GLU E 3 103 ? 100.440 -19.887 5.656 1.00 85.04 ? 83 GLU L CG 1 ATOM 7250 C CD . GLU E 3 103 ? 101.145 -21.235 5.469 1.00 85.85 ? 83 GLU L CD 1 ATOM 7251 O OE1 . GLU E 3 103 ? 101.049 -21.821 4.367 1.00 85.92 ? 83 GLU L OE1 1 ATOM 7252 O OE2 . GLU E 3 103 ? 101.797 -21.710 6.425 1.00 86.86 ? 83 GLU L OE2 1 ATOM 7253 N N . ALA E 3 104 ? 96.876 -18.423 7.687 1.00 76.62 ? 84 ALA L N 1 ATOM 7254 C CA . ALA E 3 104 ? 96.682 -18.190 9.104 1.00 74.89 ? 84 ALA L CA 1 ATOM 7255 C C . ALA E 3 104 ? 95.292 -18.709 9.409 1.00 73.35 ? 84 ALA L C 1 ATOM 7256 O O . ALA E 3 104 ? 94.723 -19.442 8.617 1.00 73.80 ? 84 ALA L O 1 ATOM 7257 C CB . ALA E 3 104 ? 96.771 -16.708 9.395 1.00 75.17 ? 84 ALA L CB 1 ATOM 7258 N N . ASP E 3 105 ? 94.734 -18.348 10.550 1.00 72.04 ? 85 ASP L N 1 ATOM 7259 C CA . ASP E 3 105 ? 93.395 -18.810 10.856 1.00 71.37 ? 85 ASP L CA 1 ATOM 7260 C C . ASP E 3 105 ? 92.448 -17.630 10.730 1.00 68.78 ? 85 ASP L C 1 ATOM 7261 O O . ASP E 3 105 ? 92.790 -16.511 11.110 1.00 69.47 ? 85 ASP L O 1 ATOM 7262 C CB . ASP E 3 105 ? 93.360 -19.408 12.257 1.00 75.91 ? 85 ASP L CB 1 ATOM 7263 C CG . ASP E 3 105 ? 94.293 -20.608 12.393 1.00 79.97 ? 85 ASP L CG 1 ATOM 7264 O OD1 . ASP E 3 105 ? 94.130 -21.573 11.612 1.00 82.00 ? 85 ASP L OD1 1 ATOM 7265 O OD2 . ASP E 3 105 ? 95.188 -20.587 13.271 1.00 81.87 ? 85 ASP L OD2 1 ATOM 7266 N N . TYR E 3 106 ? 91.268 -17.873 10.171 1.00 64.76 ? 86 TYR L N 1 ATOM 7267 C CA . TYR E 3 106 ? 90.291 -16.812 9.986 1.00 59.94 ? 86 TYR L CA 1 ATOM 7268 C C . TYR E 3 106 ? 89.005 -17.139 10.704 1.00 57.56 ? 86 TYR L C 1 ATOM 7269 O O . TYR E 3 106 ? 88.603 -18.301 10.761 1.00 56.13 ? 86 TYR L O 1 ATOM 7270 C CB . TYR E 3 106 ? 90.020 -16.606 8.502 1.00 59.40 ? 86 TYR L CB 1 ATOM 7271 C CG . TYR E 3 106 ? 91.236 -16.155 7.734 1.00 58.57 ? 86 TYR L CG 1 ATOM 7272 C CD1 . TYR E 3 106 ? 92.259 -17.044 7.408 1.00 58.18 ? 86 TYR L CD1 1 ATOM 7273 C CD2 . TYR E 3 106 ? 91.383 -14.824 7.365 1.00 59.69 ? 86 TYR L CD2 1 ATOM 7274 C CE1 . TYR E 3 106 ? 93.400 -16.607 6.733 1.00 58.56 ? 86 TYR L CE1 1 ATOM 7275 C CE2 . TYR E 3 106 ? 92.513 -14.376 6.696 1.00 59.55 ? 86 TYR L CE2 1 ATOM 7276 C CZ . TYR E 3 106 ? 93.516 -15.267 6.385 1.00 59.07 ? 86 TYR L CZ 1 ATOM 7277 O OH . TYR E 3 106 ? 94.632 -14.788 5.744 1.00 58.53 ? 86 TYR L OH 1 ATOM 7278 N N . TYR E 3 107 ? 88.363 -16.106 11.247 1.00 55.78 ? 87 TYR L N 1 ATOM 7279 C CA . TYR E 3 107 ? 87.108 -16.265 11.988 1.00 53.65 ? 87 TYR L CA 1 ATOM 7280 C C . TYR E 3 107 ? 86.045 -15.219 11.643 1.00 51.76 ? 87 TYR L C 1 ATOM 7281 O O . TYR E 3 107 ? 86.358 -14.053 11.384 1.00 49.60 ? 87 TYR L O 1 ATOM 7282 C CB . TYR E 3 107 ? 87.353 -16.149 13.493 1.00 54.54 ? 87 TYR L CB 1 ATOM 7283 C CG . TYR E 3 107 ? 88.317 -17.128 14.104 1.00 53.97 ? 87 TYR L CG 1 ATOM 7284 C CD1 . TYR E 3 107 ? 87.876 -18.352 14.598 1.00 54.27 ? 87 TYR L CD1 1 ATOM 7285 C CD2 . TYR E 3 107 ? 89.667 -16.807 14.228 1.00 54.39 ? 87 TYR L CD2 1 ATOM 7286 C CE1 . TYR E 3 107 ? 88.753 -19.231 15.205 1.00 55.87 ? 87 TYR L CE1 1 ATOM 7287 C CE2 . TYR E 3 107 ? 90.555 -17.676 14.831 1.00 55.66 ? 87 TYR L CE2 1 ATOM 7288 C CZ . TYR E 3 107 ? 90.093 -18.887 15.317 1.00 57.71 ? 87 TYR L CZ 1 ATOM 7289 O OH . TYR E 3 107 ? 90.979 -19.763 15.904 1.00 62.58 ? 87 TYR L OH 1 ATOM 7290 N N . CYS E 3 108 ? 84.786 -15.643 11.674 1.00 50.80 ? 88 CYS L N 1 ATOM 7291 C CA . CYS E 3 108 ? 83.659 -14.746 11.425 1.00 50.63 ? 88 CYS L CA 1 ATOM 7292 C C . CYS E 3 108 ? 82.959 -14.569 12.756 1.00 48.84 ? 88 CYS L C 1 ATOM 7293 O O . CYS E 3 108 ? 82.975 -15.472 13.597 1.00 47.26 ? 88 CYS L O 1 ATOM 7294 C CB . CYS E 3 108 ? 82.670 -15.335 10.415 1.00 52.65 ? 88 CYS L CB 1 ATOM 7295 S SG . CYS E 3 108 ? 82.008 -16.987 10.821 1.00 58.67 ? 88 CYS L SG 1 ATOM 7296 N N . ALA E 3 109 ? 82.357 -13.404 12.955 1.00 47.34 ? 89 ALA L N 1 ATOM 7297 C CA . ALA E 3 109 ? 81.658 -13.136 14.197 1.00 46.25 ? 89 ALA L CA 1 ATOM 7298 C C . ALA E 3 109 ? 80.586 -12.078 14.001 1.00 45.63 ? 89 ALA L C 1 ATOM 7299 O O . ALA E 3 109 ? 80.731 -11.185 13.153 1.00 44.67 ? 89 ALA L O 1 ATOM 7300 C CB . ALA E 3 109 ? 82.645 -12.683 15.263 1.00 45.12 ? 89 ALA L CB 1 ATOM 7301 N N . THR E 3 110 ? 79.513 -12.209 14.782 1.00 43.03 ? 90 THR L N 1 ATOM 7302 C CA . THR E 3 110 ? 78.393 -11.274 14.779 1.00 42.61 ? 90 THR L CA 1 ATOM 7303 C C . THR E 3 110 ? 77.709 -11.414 16.105 1.00 41.83 ? 90 THR L C 1 ATOM 7304 O O . THR E 3 110 ? 78.054 -12.277 16.909 1.00 42.45 ? 90 THR L O 1 ATOM 7305 C CB . THR E 3 110 ? 77.310 -11.605 13.756 1.00 43.72 ? 90 THR L CB 1 ATOM 7306 O OG1 . THR E 3 110 ? 76.783 -12.905 14.038 1.00 43.42 ? 90 THR L OG1 1 ATOM 7307 C CG2 . THR E 3 110 ? 77.850 -11.555 12.351 1.00 46.42 ? 90 THR L CG2 1 ATOM 7308 N N . TRP E 3 111 ? 76.711 -10.573 16.317 1.00 39.79 ? 91 TRP L N 1 ATOM 7309 C CA . TRP E 3 111 ? 75.942 -10.611 17.539 1.00 39.03 ? 91 TRP L CA 1 ATOM 7310 C C . TRP E 3 111 ? 74.851 -11.634 17.306 1.00 40.41 ? 91 TRP L C 1 ATOM 7311 O O . TRP E 3 111 ? 74.377 -11.766 16.185 1.00 40.36 ? 91 TRP L O 1 ATOM 7312 C CB . TRP E 3 111 ? 75.320 -9.248 17.779 1.00 37.67 ? 91 TRP L CB 1 ATOM 7313 C CG . TRP E 3 111 ? 74.561 -9.138 19.044 1.00 34.27 ? 91 TRP L CG 1 ATOM 7314 C CD1 . TRP E 3 111 ? 73.213 -9.215 19.203 1.00 33.35 ? 91 TRP L CD1 1 ATOM 7315 C CD2 . TRP E 3 111 ? 75.107 -8.918 20.338 1.00 33.96 ? 91 TRP L CD2 1 ATOM 7316 N NE1 . TRP E 3 111 ? 72.880 -9.053 20.522 1.00 32.52 ? 91 TRP L NE1 1 ATOM 7317 C CE2 . TRP E 3 111 ? 74.027 -8.869 21.245 1.00 33.52 ? 91 TRP L CE2 1 ATOM 7318 C CE3 . TRP E 3 111 ? 76.409 -8.758 20.827 1.00 34.45 ? 91 TRP L CE3 1 ATOM 7319 C CZ2 . TRP E 3 111 ? 74.206 -8.666 22.618 1.00 33.10 ? 91 TRP L CZ2 1 ATOM 7320 C CZ3 . TRP E 3 111 ? 76.587 -8.555 22.203 1.00 35.06 ? 91 TRP L CZ3 1 ATOM 7321 C CH2 . TRP E 3 111 ? 75.489 -8.513 23.076 1.00 31.01 ? 91 TRP L CH2 1 ATOM 7322 N N . ASP E 3 112 ? 74.459 -12.365 18.345 1.00 41.51 ? 92 ASP L N 1 ATOM 7323 C CA . ASP E 3 112 ? 73.396 -13.352 18.204 1.00 43.98 ? 92 ASP L CA 1 ATOM 7324 C C . ASP E 3 112 ? 72.275 -12.928 19.132 1.00 46.40 ? 92 ASP L C 1 ATOM 7325 O O . ASP E 3 112 ? 72.418 -13.034 20.344 1.00 48.77 ? 92 ASP L O 1 ATOM 7326 C CB . ASP E 3 112 ? 73.891 -14.732 18.606 1.00 44.29 ? 92 ASP L CB 1 ATOM 7327 C CG . ASP E 3 112 ? 72.871 -15.813 18.336 1.00 46.37 ? 92 ASP L CG 1 ATOM 7328 O OD1 . ASP E 3 112 ? 72.857 -16.351 17.205 1.00 44.75 ? 92 ASP L OD1 1 ATOM 7329 O OD2 . ASP E 3 112 ? 72.074 -16.114 19.256 1.00 48.64 ? 92 ASP L OD2 1 ATOM 7330 N N . ASP E 3 113 ? 71.162 -12.458 18.573 1.00 47.68 ? 93 ASP L N 1 ATOM 7331 C CA . ASP E 3 113 ? 70.046 -11.976 19.383 1.00 49.07 ? 93 ASP L CA 1 ATOM 7332 C C . ASP E 3 113 ? 69.367 -13.025 20.232 1.00 49.42 ? 93 ASP L C 1 ATOM 7333 O O . ASP E 3 113 ? 68.592 -12.695 21.124 1.00 48.58 ? 93 ASP L O 1 ATOM 7334 C CB . ASP E 3 113 ? 69.007 -11.304 18.503 1.00 50.56 ? 93 ASP L CB 1 ATOM 7335 C CG . ASP E 3 113 ? 69.614 -10.283 17.591 1.00 54.05 ? 93 ASP L CG 1 ATOM 7336 O OD1 . ASP E 3 113 ? 70.372 -10.698 16.688 1.00 55.16 ? 93 ASP L OD1 1 ATOM 7337 O OD2 . ASP E 3 113 ? 69.345 -9.075 17.781 1.00 56.22 ? 93 ASP L OD2 1 ATOM 7338 N N . SER E 3 114 ? 69.645 -14.289 19.952 1.00 51.16 ? 94 SER L N 1 ATOM 7339 C CA . SER E 3 114 ? 69.054 -15.368 20.724 1.00 52.62 ? 94 SER L CA 1 ATOM 7340 C C . SER E 3 114 ? 69.781 -15.492 22.053 1.00 52.30 ? 94 SER L C 1 ATOM 7341 O O . SER E 3 114 ? 69.161 -15.587 23.112 1.00 50.12 ? 94 SER L O 1 ATOM 7342 C CB . SER E 3 114 ? 69.169 -16.689 19.973 1.00 54.51 ? 94 SER L CB 1 ATOM 7343 O OG . SER E 3 114 ? 69.040 -17.771 20.881 1.00 58.65 ? 94 SER L OG 1 ATOM 7344 N N . LEU E 3 115 ? 71.106 -15.480 21.984 1.00 52.78 ? 95 LEU L N 1 ATOM 7345 C CA . LEU E 3 115 ? 71.924 -15.605 23.176 1.00 55.09 ? 95 LEU L CA 1 ATOM 7346 C C . LEU E 3 115 ? 72.246 -14.250 23.784 1.00 55.59 ? 95 LEU L C 1 ATOM 7347 O O . LEU E 3 115 ? 72.572 -14.163 24.962 1.00 56.17 ? 95 LEU L O 1 ATOM 7348 C CB . LEU E 3 115 ? 73.231 -16.314 22.835 1.00 57.22 ? 95 LEU L CB 1 ATOM 7349 C CG . LEU E 3 115 ? 73.192 -17.391 21.749 1.00 59.29 ? 95 LEU L CG 1 ATOM 7350 C CD1 . LEU E 3 115 ? 74.585 -18.002 21.616 1.00 60.15 ? 95 LEU L CD1 1 ATOM 7351 C CD2 . LEU E 3 115 ? 72.167 -18.464 22.089 1.00 60.65 ? 95 LEU L CD2 1 ATOM 7352 N N . SER E 3 116 A 72.148 -13.199 22.972 1.00 55.86 ? 95 SER L N 1 ATOM 7353 C CA . SER E 3 116 A 72.457 -11.830 23.396 1.00 55.00 ? 95 SER L CA 1 ATOM 7354 C C . SER E 3 116 A 73.930 -11.740 23.761 1.00 53.64 ? 95 SER L C 1 ATOM 7355 O O . SER E 3 116 A 74.292 -11.298 24.848 1.00 52.63 ? 95 SER L O 1 ATOM 7356 C CB . SER E 3 116 A 71.589 -11.411 24.587 1.00 55.48 ? 95 SER L CB 1 ATOM 7357 O OG . SER E 3 116 A 70.241 -11.225 24.190 1.00 56.39 ? 95 SER L OG 1 ATOM 7358 N N . ALA E 3 117 B 74.775 -12.165 22.827 1.00 54.08 ? 95 ALA L N 1 ATOM 7359 C CA . ALA E 3 117 B 76.217 -12.161 23.032 1.00 54.88 ? 95 ALA L CA 1 ATOM 7360 C C . ALA E 3 117 B 76.966 -12.302 21.711 1.00 54.16 ? 95 ALA L C 1 ATOM 7361 O O . ALA E 3 117 B 76.396 -12.771 20.722 1.00 54.54 ? 95 ALA L O 1 ATOM 7362 C CB . ALA E 3 117 B 76.598 -13.303 23.959 1.00 56.09 ? 95 ALA L CB 1 ATOM 7363 N N . VAL E 3 118 ? 78.234 -11.886 21.698 1.00 52.00 ? 96 VAL L N 1 ATOM 7364 C CA . VAL E 3 118 ? 79.058 -12.003 20.501 1.00 50.67 ? 96 VAL L CA 1 ATOM 7365 C C . VAL E 3 118 ? 79.335 -13.492 20.366 1.00 51.04 ? 96 VAL L C 1 ATOM 7366 O O . VAL E 3 118 ? 79.304 -14.222 21.360 1.00 51.33 ? 96 VAL L O 1 ATOM 7367 C CB . VAL E 3 118 ? 80.396 -11.239 20.638 1.00 50.14 ? 96 VAL L CB 1 ATOM 7368 C CG1 . VAL E 3 118 ? 81.221 -11.411 19.392 1.00 48.11 ? 96 VAL L CG1 1 ATOM 7369 C CG2 . VAL E 3 118 ? 80.137 -9.766 20.859 1.00 50.67 ? 96 VAL L CG2 1 ATOM 7370 N N . ILE E 3 119 ? 79.592 -13.940 19.140 1.00 51.19 ? 97 ILE L N 1 ATOM 7371 C CA . ILE E 3 119 ? 79.843 -15.355 18.850 1.00 49.65 ? 97 ILE L CA 1 ATOM 7372 C C . ILE E 3 119 ? 80.822 -15.456 17.690 1.00 48.00 ? 97 ILE L C 1 ATOM 7373 O O . ILE E 3 119 ? 80.824 -14.597 16.812 1.00 48.04 ? 97 ILE L O 1 ATOM 7374 C CB . ILE E 3 119 ? 78.529 -16.080 18.415 1.00 49.91 ? 97 ILE L CB 1 ATOM 7375 C CG1 . ILE E 3 119 ? 77.475 -16.030 19.527 1.00 49.07 ? 97 ILE L CG1 1 ATOM 7376 C CG2 . ILE E 3 119 ? 78.823 -17.515 18.068 1.00 51.99 ? 97 ILE L CG2 1 ATOM 7377 C CD1 . ILE E 3 119 ? 77.848 -16.777 20.778 1.00 47.03 ? 97 ILE L CD1 1 ATOM 7378 N N . PHE E 3 120 ? 81.656 -16.491 17.688 1.00 46.79 ? 98 PHE L N 1 ATOM 7379 C CA . PHE E 3 120 ? 82.605 -16.696 16.590 1.00 46.16 ? 98 PHE L CA 1 ATOM 7380 C C . PHE E 3 120 ? 82.357 -18.056 16.006 1.00 47.85 ? 98 PHE L C 1 ATOM 7381 O O . PHE E 3 120 ? 81.702 -18.888 16.615 1.00 47.95 ? 98 PHE L O 1 ATOM 7382 C CB . PHE E 3 120 ? 84.060 -16.678 17.047 1.00 41.01 ? 98 PHE L CB 1 ATOM 7383 C CG . PHE E 3 120 ? 84.505 -15.383 17.614 1.00 37.32 ? 98 PHE L CG 1 ATOM 7384 C CD1 . PHE E 3 120 ? 84.086 -14.981 18.867 1.00 36.98 ? 98 PHE L CD1 1 ATOM 7385 C CD2 . PHE E 3 120 ? 85.378 -14.574 16.906 1.00 35.93 ? 98 PHE L CD2 1 ATOM 7386 C CE1 . PHE E 3 120 ? 84.539 -13.782 19.413 1.00 38.20 ? 98 PHE L CE1 1 ATOM 7387 C CE2 . PHE E 3 120 ? 85.839 -13.376 17.439 1.00 36.03 ? 98 PHE L CE2 1 ATOM 7388 C CZ . PHE E 3 120 ? 85.422 -12.977 18.692 1.00 36.24 ? 98 PHE L CZ 1 ATOM 7389 N N . GLY E 3 121 ? 82.890 -18.286 14.817 1.00 52.04 ? 99 GLY L N 1 ATOM 7390 C CA . GLY E 3 121 ? 82.731 -19.587 14.201 1.00 54.34 ? 99 GLY L CA 1 ATOM 7391 C C . GLY E 3 121 ? 83.816 -20.438 14.821 1.00 56.04 ? 99 GLY L C 1 ATOM 7392 O O . GLY E 3 121 ? 84.498 -19.997 15.755 1.00 55.79 ? 99 GLY L O 1 ATOM 7393 N N . GLY E 3 122 ? 83.983 -21.655 14.325 1.00 56.98 ? 100 GLY L N 1 ATOM 7394 C CA . GLY E 3 122 ? 85.023 -22.501 14.873 1.00 58.57 ? 100 GLY L CA 1 ATOM 7395 C C . GLY E 3 122 ? 86.378 -21.981 14.439 1.00 59.01 ? 100 GLY L C 1 ATOM 7396 O O . GLY E 3 122 ? 87.323 -21.946 15.219 1.00 60.15 ? 100 GLY L O 1 ATOM 7397 N N . GLY E 3 123 ? 86.455 -21.551 13.185 1.00 59.33 ? 101 GLY L N 1 ATOM 7398 C CA . GLY E 3 123 ? 87.695 -21.051 12.632 1.00 59.30 ? 101 GLY L CA 1 ATOM 7399 C C . GLY E 3 123 ? 88.001 -21.840 11.378 1.00 60.90 ? 101 GLY L C 1 ATOM 7400 O O . GLY E 3 123 ? 87.483 -22.944 11.179 1.00 60.77 ? 101 GLY L O 1 ATOM 7401 N N . THR E 3 124 ? 88.832 -21.278 10.516 1.00 62.80 ? 102 THR L N 1 ATOM 7402 C CA . THR E 3 124 ? 89.197 -21.963 9.287 1.00 64.94 ? 102 THR L CA 1 ATOM 7403 C C . THR E 3 124 ? 90.716 -21.926 9.125 1.00 67.33 ? 102 THR L C 1 ATOM 7404 O O . THR E 3 124 ? 91.340 -20.870 9.246 1.00 66.99 ? 102 THR L O 1 ATOM 7405 C CB . THR E 3 124 ? 88.485 -21.317 8.083 1.00 64.21 ? 102 THR L CB 1 ATOM 7406 O OG1 . THR E 3 124 ? 87.070 -21.518 8.210 1.00 62.29 ? 102 THR L OG1 1 ATOM 7407 C CG2 . THR E 3 124 ? 88.960 -21.929 6.783 1.00 63.83 ? 102 THR L CG2 1 ATOM 7408 N N . LYS E 3 125 ? 91.306 -23.090 8.860 1.00 70.54 ? 103 LYS L N 1 ATOM 7409 C CA . LYS E 3 125 ? 92.751 -23.194 8.723 1.00 73.88 ? 103 LYS L CA 1 ATOM 7410 C C . LYS E 3 125 ? 93.355 -22.439 7.550 1.00 75.54 ? 103 LYS L C 1 ATOM 7411 O O . LYS E 3 125 ? 93.966 -21.397 7.748 1.00 75.58 ? 103 LYS L O 1 ATOM 7412 C CB . LYS E 3 125 ? 93.184 -24.657 8.662 1.00 75.28 ? 103 LYS L CB 1 ATOM 7413 C CG . LYS E 3 125 ? 94.620 -24.849 9.126 1.00 76.17 ? 103 LYS L CG 1 ATOM 7414 C CD . LYS E 3 125 ? 94.784 -24.312 10.543 1.00 77.82 ? 103 LYS L CD 1 ATOM 7415 C CE . LYS E 3 125 ? 96.246 -24.200 10.941 1.00 80.70 ? 103 LYS L CE 1 ATOM 7416 N NZ . LYS E 3 125 ? 96.413 -23.676 12.333 1.00 81.22 ? 103 LYS L NZ 1 ATOM 7417 N N . LEU E 3 126 ? 93.208 -22.956 6.335 1.00 77.41 ? 104 LEU L N 1 ATOM 7418 C CA . LEU E 3 126 ? 93.772 -22.272 5.167 1.00 80.45 ? 104 LEU L CA 1 ATOM 7419 C C . LEU E 3 126 ? 95.301 -22.217 5.188 1.00 83.59 ? 104 LEU L C 1 ATOM 7420 O O . LEU E 3 126 ? 95.911 -21.556 6.038 1.00 82.34 ? 104 LEU L O 1 ATOM 7421 C CB . LEU E 3 126 ? 93.212 -20.843 5.061 1.00 77.97 ? 104 LEU L CB 1 ATOM 7422 C CG . LEU E 3 126 ? 93.720 -19.825 4.024 1.00 74.81 ? 104 LEU L CG 1 ATOM 7423 C CD1 . LEU E 3 126 ? 95.002 -19.189 4.498 1.00 73.83 ? 104 LEU L CD1 1 ATOM 7424 C CD2 . LEU E 3 126 ? 93.901 -20.484 2.678 1.00 73.81 ? 104 LEU L CD2 1 ATOM 7425 N N . THR E 3 127 ? 95.909 -22.914 4.232 1.00 87.46 ? 105 THR L N 1 ATOM 7426 C CA . THR E 3 127 ? 97.360 -22.959 4.106 1.00 90.63 ? 105 THR L CA 1 ATOM 7427 C C . THR E 3 127 ? 97.765 -22.895 2.636 1.00 92.62 ? 105 THR L C 1 ATOM 7428 O O . THR E 3 127 ? 97.489 -23.814 1.869 1.00 92.53 ? 105 THR L O 1 ATOM 7429 C CB . THR E 3 127 ? 97.927 -24.248 4.731 1.00 90.71 ? 105 THR L CB 1 ATOM 7430 O OG1 . THR E 3 127 ? 97.185 -25.375 4.251 1.00 89.90 ? 105 THR L OG1 1 ATOM 7431 C CG2 . THR E 3 127 ? 97.836 -24.190 6.255 1.00 91.65 ? 105 THR L CG2 1 ATOM 7432 N N . VAL E 3 128 ? 98.408 -21.800 2.247 1.00 95.39 ? 106 VAL L N 1 ATOM 7433 C CA . VAL E 3 128 ? 98.850 -21.628 0.872 1.00 99.72 ? 106 VAL L CA 1 ATOM 7434 C C . VAL E 3 128 ? 99.874 -22.718 0.532 1.00 103.25 ? 106 VAL L C 1 ATOM 7435 O O . VAL E 3 128 ? 101.014 -22.676 0.997 1.00 104.38 ? 106 VAL L O 1 ATOM 7436 C CB . VAL E 3 128 ? 99.467 -20.218 0.673 1.00 99.23 ? 106 VAL L CB 1 ATOM 7437 C CG1 . VAL E 3 128 ? 100.611 -19.992 1.646 1.00 99.65 ? 106 VAL L CG1 1 ATOM 7438 C CG2 . VAL E 3 128 ? 99.946 -20.058 -0.749 1.00 100.18 ? 106 VAL L CG2 1 ATOM 7439 N N . LEU E 3 129 ? 99.457 -23.694 -0.276 1.00 106.81 ? 107 LEU L N 1 ATOM 7440 C CA . LEU E 3 129 ? 100.323 -24.814 -0.660 1.00 110.50 ? 107 LEU L CA 1 ATOM 7441 C C . LEU E 3 129 ? 101.473 -24.415 -1.588 1.00 113.37 ? 107 LEU L C 1 ATOM 7442 O O . LEU E 3 129 ? 101.259 -23.804 -2.636 1.00 113.17 ? 107 LEU L O 1 ATOM 7443 C CB . LEU E 3 129 ? 99.491 -25.920 -1.323 1.00 109.85 ? 107 LEU L CB 1 ATOM 7444 C CG . LEU E 3 129 ? 100.025 -27.362 -1.291 1.00 110.40 ? 107 LEU L CG 1 ATOM 7445 C CD1 . LEU E 3 129 ? 101.404 -27.455 -1.938 1.00 109.56 ? 107 LEU L CD1 1 ATOM 7446 C CD2 . LEU E 3 129 ? 100.084 -27.842 0.150 1.00 109.95 ? 107 LEU L CD2 1 ATOM 7447 N N . GLY E 3 130 ? 102.692 -24.781 -1.191 1.00 116.84 ? 108 GLY L N 1 ATOM 7448 C CA . GLY E 3 130 ? 103.877 -24.467 -1.974 1.00 120.59 ? 108 GLY L CA 1 ATOM 7449 C C . GLY E 3 130 ? 105.170 -24.787 -1.238 1.00 123.35 ? 108 GLY L C 1 ATOM 7450 O O . GLY E 3 130 ? 105.193 -25.666 -0.374 1.00 122.99 ? 108 GLY L O 1 ATOM 7451 N N . GLN E 3 131 ? 106.241 -24.069 -1.582 1.00 126.25 ? 109 GLN L N 1 ATOM 7452 C CA . GLN E 3 131 ? 107.562 -24.251 -0.974 1.00 129.34 ? 109 GLN L CA 1 ATOM 7453 C C . GLN E 3 131 ? 107.845 -25.704 -0.598 1.00 131.16 ? 109 GLN L C 1 ATOM 7454 O O . GLN E 3 131 ? 107.824 -26.057 0.581 1.00 131.84 ? 109 GLN L O 1 ATOM 7455 C CB . GLN E 3 131 ? 107.702 -23.399 0.292 1.00 130.44 ? 109 GLN L CB 1 ATOM 7456 C CG . GLN E 3 131 ? 107.370 -21.925 0.142 1.00 131.88 ? 109 GLN L CG 1 ATOM 7457 C CD . GLN E 3 131 ? 107.611 -21.151 1.433 1.00 132.59 ? 109 GLN L CD 1 ATOM 7458 O OE1 . GLN E 3 131 ? 107.102 -21.515 2.498 1.00 132.47 ? 109 GLN L OE1 1 ATOM 7459 N NE2 . GLN E 3 131 ? 108.389 -20.079 1.341 1.00 132.93 ? 109 GLN L NE2 1 ATOM 7460 N N . PRO E 3 132 ? 108.119 -26.568 -1.589 1.00 132.73 ? 110 PRO L N 1 ATOM 7461 C CA . PRO E 3 132 ? 108.400 -27.980 -1.299 1.00 133.82 ? 110 PRO L CA 1 ATOM 7462 C C . PRO E 3 132 ? 109.758 -28.199 -0.626 1.00 134.73 ? 110 PRO L C 1 ATOM 7463 O O . PRO E 3 132 ? 110.172 -29.338 -0.387 1.00 134.64 ? 110 PRO L O 1 ATOM 7464 C CB . PRO E 3 132 ? 108.323 -28.633 -2.678 1.00 133.60 ? 110 PRO L CB 1 ATOM 7465 C CG . PRO E 3 132 ? 108.847 -27.553 -3.576 1.00 133.23 ? 110 PRO L CG 1 ATOM 7466 C CD . PRO E 3 132 ? 108.146 -26.315 -3.042 1.00 133.19 ? 110 PRO L CD 1 ATOM 7467 N N . LYS E 3 133 A 110.437 -27.099 -0.313 1.00 135.56 ? 110 LYS L N 1 ATOM 7468 C CA . LYS E 3 133 A 111.756 -27.148 0.308 1.00 136.24 ? 110 LYS L CA 1 ATOM 7469 C C . LYS E 3 133 A 111.707 -27.122 1.841 1.00 136.86 ? 110 LYS L C 1 ATOM 7470 O O . LYS E 3 133 A 111.506 -26.065 2.447 1.00 136.88 ? 110 LYS L O 1 ATOM 7471 C CB . LYS E 3 133 A 112.605 -25.977 -0.205 1.00 136.06 ? 110 LYS L CB 1 ATOM 7472 C CG . LYS E 3 133 A 112.637 -25.819 -1.736 1.00 135.82 ? 110 LYS L CG 1 ATOM 7473 C CD . LYS E 3 133 A 113.207 -27.051 -2.443 1.00 135.41 ? 110 LYS L CD 1 ATOM 7474 C CE . LYS E 3 133 A 113.495 -26.787 -3.925 1.00 134.71 ? 110 LYS L CE 1 ATOM 7475 N NZ . LYS E 3 133 A 112.286 -26.448 -4.727 1.00 133.83 ? 110 LYS L NZ 1 ATOM 7476 N N . ALA E 3 134 ? 111.900 -28.289 2.457 1.00 137.49 ? 111 ALA L N 1 ATOM 7477 C CA . ALA E 3 134 ? 111.892 -28.428 3.917 1.00 137.70 ? 111 ALA L CA 1 ATOM 7478 C C . ALA E 3 134 ? 113.187 -29.074 4.406 1.00 137.85 ? 111 ALA L C 1 ATOM 7479 O O . ALA E 3 134 ? 113.250 -30.292 4.580 1.00 137.90 ? 111 ALA L O 1 ATOM 7480 C CB . ALA E 3 134 ? 110.707 -29.275 4.353 1.00 137.49 ? 111 ALA L CB 1 ATOM 7481 N N . ALA E 3 135 ? 114.211 -28.253 4.631 1.00 137.81 ? 112 ALA L N 1 ATOM 7482 C CA . ALA E 3 135 ? 115.510 -28.738 5.086 1.00 137.44 ? 112 ALA L CA 1 ATOM 7483 C C . ALA E 3 135 ? 115.640 -28.678 6.605 1.00 137.40 ? 112 ALA L C 1 ATOM 7484 O O . ALA E 3 135 ? 116.080 -27.668 7.158 1.00 137.17 ? 112 ALA L O 1 ATOM 7485 C CB . ALA E 3 135 ? 116.624 -27.920 4.437 1.00 137.03 ? 112 ALA L CB 1 ATOM 7486 N N . PRO E 3 136 ? 115.263 -29.767 7.301 1.00 137.48 ? 113 PRO L N 1 ATOM 7487 C CA . PRO E 3 136 ? 115.346 -29.817 8.764 1.00 137.59 ? 113 PRO L CA 1 ATOM 7488 C C . PRO E 3 136 ? 116.787 -29.922 9.274 1.00 137.64 ? 113 PRO L C 1 ATOM 7489 O O . PRO E 3 136 ? 117.311 -31.022 9.457 1.00 137.73 ? 113 PRO L O 1 ATOM 7490 C CB . PRO E 3 136 ? 114.509 -31.047 9.109 1.00 137.41 ? 113 PRO L CB 1 ATOM 7491 C CG . PRO E 3 136 ? 114.779 -31.954 7.954 1.00 137.25 ? 113 PRO L CG 1 ATOM 7492 C CD . PRO E 3 136 ? 114.690 -31.018 6.769 1.00 137.35 ? 113 PRO L CD 1 ATOM 7493 N N . SER E 3 137 ? 117.415 -28.770 9.501 1.00 137.40 ? 114 SER L N 1 ATOM 7494 C CA . SER E 3 137 ? 118.793 -28.709 9.985 1.00 136.78 ? 114 SER L CA 1 ATOM 7495 C C . SER E 3 137 ? 118.886 -29.128 11.451 1.00 136.57 ? 114 SER L C 1 ATOM 7496 O O . SER E 3 137 ? 119.196 -28.315 12.326 1.00 136.22 ? 114 SER L O 1 ATOM 7497 C CB . SER E 3 137 ? 119.339 -27.292 9.811 1.00 136.48 ? 114 SER L CB 1 ATOM 7498 O OG . SER E 3 137 ? 119.272 -26.896 8.452 1.00 136.13 ? 114 SER L OG 1 ATOM 7499 N N . VAL E 3 138 ? 118.627 -30.409 11.699 1.00 136.39 ? 115 VAL L N 1 ATOM 7500 C CA . VAL E 3 138 ? 118.650 -30.983 13.041 1.00 136.04 ? 115 VAL L CA 1 ATOM 7501 C C . VAL E 3 138 ? 119.967 -30.749 13.784 1.00 135.57 ? 115 VAL L C 1 ATOM 7502 O O . VAL E 3 138 ? 121.024 -30.585 13.171 1.00 134.96 ? 115 VAL L O 1 ATOM 7503 C CB . VAL E 3 138 ? 118.359 -32.507 12.986 1.00 136.11 ? 115 VAL L CB 1 ATOM 7504 C CG1 . VAL E 3 138 ? 119.502 -33.228 12.292 1.00 136.26 ? 115 VAL L CG1 1 ATOM 7505 C CG2 . VAL E 3 138 ? 118.137 -33.055 14.387 1.00 135.83 ? 115 VAL L CG2 1 ATOM 7506 N N . THR E 3 139 ? 119.882 -30.736 15.112 1.00 135.07 ? 116 THR L N 1 ATOM 7507 C CA . THR E 3 139 ? 121.042 -30.520 15.966 1.00 134.58 ? 116 THR L CA 1 ATOM 7508 C C . THR E 3 139 ? 120.859 -31.230 17.306 1.00 134.46 ? 116 THR L C 1 ATOM 7509 O O . THR E 3 139 ? 119.793 -31.153 17.913 1.00 134.39 ? 116 THR L O 1 ATOM 7510 C CB . THR E 3 139 ? 121.253 -29.025 16.229 1.00 134.41 ? 116 THR L CB 1 ATOM 7511 O OG1 . THR E 3 139 ? 121.347 -28.329 14.980 1.00 134.42 ? 116 THR L OG1 1 ATOM 7512 C CG2 . THR E 3 139 ? 122.524 -28.807 17.019 1.00 134.22 ? 116 THR L CG2 1 ATOM 7513 N N . LEU E 3 140 ? 121.902 -31.917 17.765 1.00 134.48 ? 117 LEU L N 1 ATOM 7514 C CA . LEU E 3 140 ? 121.846 -32.647 19.029 1.00 134.31 ? 117 LEU L CA 1 ATOM 7515 C C . LEU E 3 140 ? 122.851 -32.069 20.025 1.00 134.77 ? 117 LEU L C 1 ATOM 7516 O O . LEU E 3 140 ? 123.941 -31.644 19.640 1.00 134.98 ? 117 LEU L O 1 ATOM 7517 C CB . LEU E 3 140 ? 122.158 -34.126 18.785 1.00 133.41 ? 117 LEU L CB 1 ATOM 7518 C CG . LEU E 3 140 ? 121.609 -35.177 19.756 1.00 133.18 ? 117 LEU L CG 1 ATOM 7519 C CD1 . LEU E 3 140 ? 121.964 -34.831 21.190 1.00 133.06 ? 117 LEU L CD1 1 ATOM 7520 C CD2 . LEU E 3 140 ? 120.108 -35.255 19.598 1.00 133.36 ? 117 LEU L CD2 1 ATOM 7521 N N . PHE E 3 141 ? 122.481 -32.053 21.303 1.00 135.00 ? 118 PHE L N 1 ATOM 7522 C CA . PHE E 3 141 ? 123.358 -31.538 22.350 1.00 135.62 ? 118 PHE L CA 1 ATOM 7523 C C . PHE E 3 141 ? 123.525 -32.524 23.507 1.00 135.87 ? 118 PHE L C 1 ATOM 7524 O O . PHE E 3 141 ? 122.539 -33.020 24.052 1.00 136.17 ? 118 PHE L O 1 ATOM 7525 C CB . PHE E 3 141 ? 122.814 -30.220 22.911 1.00 136.03 ? 118 PHE L CB 1 ATOM 7526 C CG . PHE E 3 141 ? 123.119 -29.017 22.063 1.00 136.96 ? 118 PHE L CG 1 ATOM 7527 C CD1 . PHE E 3 141 ? 122.486 -28.824 20.840 1.00 137.61 ? 118 PHE L CD1 1 ATOM 7528 C CD2 . PHE E 3 141 ? 124.031 -28.061 22.500 1.00 137.08 ? 118 PHE L CD2 1 ATOM 7529 C CE1 . PHE E 3 141 ? 122.757 -27.691 20.067 1.00 137.79 ? 118 PHE L CE1 1 ATOM 7530 C CE2 . PHE E 3 141 ? 124.309 -26.928 21.736 1.00 137.21 ? 118 PHE L CE2 1 ATOM 7531 C CZ . PHE E 3 141 ? 123.671 -26.743 20.518 1.00 137.32 ? 118 PHE L CZ 1 ATOM 7532 N N . PRO E 3 142 ? 124.781 -32.832 23.884 1.00 135.98 ? 119 PRO L N 1 ATOM 7533 C CA . PRO E 3 142 ? 125.081 -33.757 24.987 1.00 135.66 ? 119 PRO L CA 1 ATOM 7534 C C . PRO E 3 142 ? 124.870 -33.031 26.317 1.00 135.37 ? 119 PRO L C 1 ATOM 7535 O O . PRO E 3 142 ? 125.191 -31.847 26.431 1.00 135.72 ? 119 PRO L O 1 ATOM 7536 C CB . PRO E 3 142 ? 126.552 -34.106 24.761 1.00 135.96 ? 119 PRO L CB 1 ATOM 7537 C CG . PRO E 3 142 ? 126.754 -33.867 23.288 1.00 136.20 ? 119 PRO L CG 1 ATOM 7538 C CD . PRO E 3 142 ? 125.987 -32.592 23.075 1.00 136.06 ? 119 PRO L CD 1 ATOM 7539 N N . PRO E 3 143 ? 124.349 -33.728 27.343 1.00 134.81 ? 120 PRO L N 1 ATOM 7540 C CA . PRO E 3 143 ? 124.125 -33.066 28.635 1.00 134.71 ? 120 PRO L CA 1 ATOM 7541 C C . PRO E 3 143 ? 125.285 -32.192 29.113 1.00 134.79 ? 120 PRO L C 1 ATOM 7542 O O . PRO E 3 143 ? 126.378 -32.233 28.549 1.00 134.46 ? 120 PRO L O 1 ATOM 7543 C CB . PRO E 3 143 ? 123.826 -34.236 29.581 1.00 134.15 ? 120 PRO L CB 1 ATOM 7544 C CG . PRO E 3 143 ? 124.488 -35.405 28.924 1.00 134.12 ? 120 PRO L CG 1 ATOM 7545 C CD . PRO E 3 143 ? 124.186 -35.185 27.469 1.00 134.21 ? 120 PRO L CD 1 ATOM 7546 N N . SER E 3 144 ? 125.033 -31.388 30.143 1.00 135.24 ? 121 SER L N 1 ATOM 7547 C CA . SER E 3 144 ? 126.053 -30.501 30.698 1.00 135.79 ? 121 SER L CA 1 ATOM 7548 C C . SER E 3 144 ? 126.756 -31.153 31.890 1.00 136.57 ? 121 SER L C 1 ATOM 7549 O O . SER E 3 144 ? 126.300 -32.175 32.409 1.00 136.68 ? 121 SER L O 1 ATOM 7550 C CB . SER E 3 144 ? 125.421 -29.177 31.142 1.00 135.24 ? 121 SER L CB 1 ATOM 7551 O OG . SER E 3 144 ? 124.835 -28.493 30.049 1.00 134.08 ? 121 SER L OG 1 ATOM 7552 N N . SER E 3 145 ? 127.869 -30.561 32.315 1.00 137.07 ? 122 SER L N 1 ATOM 7553 C CA . SER E 3 145 ? 128.621 -31.083 33.451 1.00 137.50 ? 122 SER L CA 1 ATOM 7554 C C . SER E 3 145 ? 127.867 -30.769 34.742 1.00 137.45 ? 122 SER L C 1 ATOM 7555 O O . SER E 3 145 ? 127.893 -31.546 35.696 1.00 137.10 ? 122 SER L O 1 ATOM 7556 C CB . SER E 3 145 ? 130.023 -30.464 33.495 1.00 137.83 ? 122 SER L CB 1 ATOM 7557 O OG . SER E 3 145 ? 129.965 -29.052 33.608 1.00 138.50 ? 122 SER L OG 1 ATOM 7558 N N . GLU E 3 146 ? 127.194 -29.623 34.759 1.00 137.55 ? 123 GLU L N 1 ATOM 7559 C CA . GLU E 3 146 ? 126.418 -29.208 35.918 1.00 137.93 ? 123 GLU L CA 1 ATOM 7560 C C . GLU E 3 146 ? 125.214 -30.129 36.079 1.00 138.50 ? 123 GLU L C 1 ATOM 7561 O O . GLU E 3 146 ? 124.722 -30.337 37.190 1.00 138.09 ? 123 GLU L O 1 ATOM 7562 C CB . GLU E 3 146 ? 125.953 -27.761 35.746 1.00 137.63 ? 123 GLU L CB 1 ATOM 7563 C CG . GLU E 3 146 ? 127.059 -26.734 35.914 1.00 137.22 ? 123 GLU L CG 1 ATOM 7564 C CD . GLU E 3 146 ? 126.644 -25.348 35.464 1.00 136.92 ? 123 GLU L CD 1 ATOM 7565 O OE1 . GLU E 3 146 ? 126.527 -25.138 34.240 1.00 136.88 ? 123 GLU L OE1 1 ATOM 7566 O OE2 . GLU E 3 146 ? 126.431 -24.471 36.329 1.00 136.65 ? 123 GLU L OE2 1 ATOM 7567 N N . GLU E 3 147 ? 124.747 -30.677 34.960 1.00 139.34 ? 124 GLU L N 1 ATOM 7568 C CA . GLU E 3 147 ? 123.608 -31.587 34.971 1.00 140.36 ? 124 GLU L CA 1 ATOM 7569 C C . GLU E 3 147 ? 124.014 -32.940 35.540 1.00 140.73 ? 124 GLU L C 1 ATOM 7570 O O . GLU E 3 147 ? 123.365 -33.457 36.450 1.00 140.87 ? 124 GLU L O 1 ATOM 7571 C CB . GLU E 3 147 ? 123.043 -31.772 33.558 1.00 140.85 ? 124 GLU L CB 1 ATOM 7572 C CG . GLU E 3 147 ? 122.402 -30.523 32.967 1.00 141.46 ? 124 GLU L CG 1 ATOM 7573 C CD . GLU E 3 147 ? 121.547 -30.827 31.751 1.00 141.67 ? 124 GLU L CD 1 ATOM 7574 O OE1 . GLU E 3 147 ? 120.553 -31.571 31.897 1.00 141.63 ? 124 GLU L OE1 1 ATOM 7575 O OE2 . GLU E 3 147 ? 121.869 -30.325 30.652 1.00 141.71 ? 124 GLU L OE2 1 ATOM 7576 N N . LEU E 3 148 ? 125.083 -33.517 34.997 1.00 141.08 ? 125 LEU L N 1 ATOM 7577 C CA . LEU E 3 148 ? 125.565 -34.803 35.484 1.00 141.30 ? 125 LEU L CA 1 ATOM 7578 C C . LEU E 3 148 ? 125.876 -34.661 36.967 1.00 141.90 ? 125 LEU L C 1 ATOM 7579 O O . LEU E 3 148 ? 125.661 -35.589 37.746 1.00 141.97 ? 125 LEU L O 1 ATOM 7580 C CB . LEU E 3 148 ? 126.812 -35.237 34.714 1.00 140.49 ? 125 LEU L CB 1 ATOM 7581 C CG . LEU E 3 148 ? 126.553 -35.745 33.295 1.00 140.03 ? 125 LEU L CG 1 ATOM 7582 C CD1 . LEU E 3 148 ? 127.874 -36.015 32.599 1.00 140.27 ? 125 LEU L CD1 1 ATOM 7583 C CD2 . LEU E 3 148 ? 125.707 -37.010 33.350 1.00 139.61 ? 125 LEU L CD2 1 ATOM 7584 N N . GLN E 3 149 ? 126.375 -33.490 37.353 1.00 142.65 ? 126 GLN L N 1 ATOM 7585 C CA . GLN E 3 149 ? 126.679 -33.219 38.752 1.00 143.39 ? 126 GLN L CA 1 ATOM 7586 C C . GLN E 3 149 ? 125.357 -32.927 39.442 1.00 143.67 ? 126 GLN L C 1 ATOM 7587 O O . GLN E 3 149 ? 125.294 -32.129 40.376 1.00 143.76 ? 126 GLN L O 1 ATOM 7588 C CB . GLN E 3 149 ? 127.609 -32.011 38.889 1.00 143.78 ? 126 GLN L CB 1 ATOM 7589 C CG . GLN E 3 149 ? 129.007 -32.234 38.336 1.00 145.02 ? 126 GLN L CG 1 ATOM 7590 C CD . GLN E 3 149 ? 129.961 -31.104 38.676 1.00 145.64 ? 126 GLN L CD 1 ATOM 7591 O OE1 . GLN E 3 149 ? 130.239 -30.841 39.848 1.00 146.13 ? 126 GLN L OE1 1 ATOM 7592 N NE2 . GLN E 3 149 ? 130.471 -30.430 37.650 1.00 145.76 ? 126 GLN L NE2 1 ATOM 7593 N N . ALA E 3 150 ? 124.301 -33.579 38.960 1.00 144.21 ? 127 ALA L N 1 ATOM 7594 C CA . ALA E 3 150 ? 122.962 -33.406 39.507 1.00 144.84 ? 127 ALA L CA 1 ATOM 7595 C C . ALA E 3 150 ? 121.981 -34.448 38.960 1.00 144.99 ? 127 ALA L C 1 ATOM 7596 O O . ALA E 3 150 ? 120.793 -34.168 38.802 1.00 145.22 ? 127 ALA L O 1 ATOM 7597 C CB . ALA E 3 150 ? 122.457 -31.997 39.203 1.00 144.89 ? 127 ALA L CB 1 ATOM 7598 N N . ASN E 3 151 ? 122.481 -35.647 38.675 1.00 145.09 ? 128 ASN L N 1 ATOM 7599 C CA . ASN E 3 151 ? 121.647 -36.730 38.159 1.00 145.50 ? 128 ASN L CA 1 ATOM 7600 C C . ASN E 3 151 ? 120.657 -36.249 37.108 1.00 145.88 ? 128 ASN L C 1 ATOM 7601 O O . ASN E 3 151 ? 119.454 -36.181 37.373 1.00 145.95 ? 128 ASN L O 1 ATOM 7602 C CB . ASN E 3 151 ? 120.858 -37.385 39.294 1.00 145.46 ? 128 ASN L CB 1 ATOM 7603 C CG . ASN E 3 151 ? 121.738 -37.828 40.439 1.00 145.43 ? 128 ASN L CG 1 ATOM 7604 O OD1 . ASN E 3 151 ? 122.689 -38.584 40.250 1.00 145.66 ? 128 ASN L OD1 1 ATOM 7605 N ND2 . ASN E 3 151 ? 121.419 -37.362 41.641 1.00 145.15 ? 128 ASN L ND2 1 ATOM 7606 N N . LYS E 3 152 ? 121.148 -35.919 35.919 1.00 146.36 ? 129 LYS L N 1 ATOM 7607 C CA . LYS E 3 152 ? 120.258 -35.455 34.862 1.00 146.95 ? 129 LYS L CA 1 ATOM 7608 C C . LYS E 3 152 ? 120.921 -35.507 33.486 1.00 146.94 ? 129 LYS L C 1 ATOM 7609 O O . LYS E 3 152 ? 121.779 -34.681 33.163 1.00 146.62 ? 129 LYS L O 1 ATOM 7610 C CB . LYS E 3 152 ? 119.790 -34.026 35.164 1.00 147.58 ? 129 LYS L CB 1 ATOM 7611 C CG . LYS E 3 152 ? 118.415 -33.666 34.599 1.00 147.63 ? 129 LYS L CG 1 ATOM 7612 C CD . LYS E 3 152 ? 117.311 -34.486 35.260 1.00 147.67 ? 129 LYS L CD 1 ATOM 7613 C CE . LYS E 3 152 ? 115.927 -34.030 34.819 1.00 147.73 ? 129 LYS L CE 1 ATOM 7614 N NZ . LYS E 3 152 ? 115.632 -32.626 35.231 1.00 147.79 ? 129 LYS L NZ 1 ATOM 7615 N N . ALA E 3 153 ? 120.519 -36.490 32.686 1.00 146.93 ? 130 ALA L N 1 ATOM 7616 C CA . ALA E 3 153 ? 121.050 -36.655 31.338 1.00 146.84 ? 130 ALA L CA 1 ATOM 7617 C C . ALA E 3 153 ? 120.000 -36.147 30.360 1.00 146.72 ? 130 ALA L C 1 ATOM 7618 O O . ALA E 3 153 ? 119.250 -36.927 29.773 1.00 146.59 ? 130 ALA L O 1 ATOM 7619 C CB . ALA E 3 153 ? 121.357 -38.121 31.066 1.00 146.54 ? 130 ALA L CB 1 ATOM 7620 N N . THR E 3 154 ? 119.949 -34.830 30.198 1.00 146.73 ? 131 THR L N 1 ATOM 7621 C CA . THR E 3 154 ? 118.985 -34.202 29.306 1.00 146.65 ? 131 THR L CA 1 ATOM 7622 C C . THR E 3 154 ? 119.601 -33.862 27.951 1.00 146.56 ? 131 THR L C 1 ATOM 7623 O O . THR E 3 154 ? 120.362 -32.900 27.828 1.00 146.12 ? 131 THR L O 1 ATOM 7624 C CB . THR E 3 154 ? 118.421 -32.906 29.931 1.00 146.86 ? 131 THR L CB 1 ATOM 7625 O OG1 . THR E 3 154 ? 117.964 -33.172 31.263 1.00 147.14 ? 131 THR L OG1 1 ATOM 7626 C CG2 . THR E 3 154 ? 117.257 -32.381 29.107 1.00 147.14 ? 131 THR L CG2 1 ATOM 7627 N N . LEU E 3 155 ? 119.272 -34.662 26.939 1.00 146.59 ? 132 LEU L N 1 ATOM 7628 C CA . LEU E 3 155 ? 119.770 -34.445 25.582 1.00 146.52 ? 132 LEU L CA 1 ATOM 7629 C C . LEU E 3 155 ? 118.765 -33.596 24.807 1.00 146.78 ? 132 LEU L C 1 ATOM 7630 O O . LEU E 3 155 ? 117.558 -33.839 24.866 1.00 146.97 ? 132 LEU L O 1 ATOM 7631 C CB . LEU E 3 155 ? 119.984 -35.784 24.871 1.00 145.81 ? 132 LEU L CB 1 ATOM 7632 C CG . LEU E 3 155 ? 121.194 -36.599 25.333 1.00 145.14 ? 132 LEU L CG 1 ATOM 7633 C CD1 . LEU E 3 155 ? 121.136 -37.997 24.749 1.00 145.07 ? 132 LEU L CD1 1 ATOM 7634 C CD2 . LEU E 3 155 ? 122.465 -35.897 24.905 1.00 144.64 ? 132 LEU L CD2 1 ATOM 7635 N N . VAL E 3 156 ? 119.267 -32.604 24.079 1.00 146.83 ? 133 VAL L N 1 ATOM 7636 C CA . VAL E 3 156 ? 118.408 -31.705 23.316 1.00 146.69 ? 133 VAL L CA 1 ATOM 7637 C C . VAL E 3 156 ? 118.604 -31.775 21.806 1.00 146.49 ? 133 VAL L C 1 ATOM 7638 O O . VAL E 3 156 ? 119.636 -31.353 21.284 1.00 146.51 ? 133 VAL L O 1 ATOM 7639 C CB . VAL E 3 156 ? 118.623 -30.241 23.753 1.00 146.82 ? 133 VAL L CB 1 ATOM 7640 C CG1 . VAL E 3 156 ? 117.727 -29.322 22.947 1.00 147.05 ? 133 VAL L CG1 1 ATOM 7641 C CG2 . VAL E 3 156 ? 118.338 -30.096 25.237 1.00 147.17 ? 133 VAL L CG2 1 ATOM 7642 N N . CYS E 3 157 ? 117.605 -32.305 21.108 1.00 146.26 ? 134 CYS L N 1 ATOM 7643 C CA . CYS E 3 157 ? 117.662 -32.396 19.656 1.00 146.11 ? 134 CYS L CA 1 ATOM 7644 C C . CYS E 3 157 ? 116.855 -31.221 19.117 1.00 145.55 ? 134 CYS L C 1 ATOM 7645 O O . CYS E 3 157 ? 115.632 -31.292 19.010 1.00 145.19 ? 134 CYS L O 1 ATOM 7646 C CB . CYS E 3 157 ? 117.060 -33.720 19.171 1.00 147.10 ? 134 CYS L CB 1 ATOM 7647 S SG . CYS E 3 157 ? 117.235 -34.042 17.380 1.00 148.73 ? 134 CYS L SG 1 ATOM 7648 N N . LEU E 3 158 ? 117.549 -30.132 18.799 1.00 144.99 ? 135 LEU L N 1 ATOM 7649 C CA . LEU E 3 158 ? 116.906 -28.933 18.276 1.00 144.23 ? 135 LEU L CA 1 ATOM 7650 C C . LEU E 3 158 ? 116.782 -28.951 16.758 1.00 144.11 ? 135 LEU L C 1 ATOM 7651 O O . LEU E 3 158 ? 117.742 -28.636 16.050 1.00 144.08 ? 135 LEU L O 1 ATOM 7652 C CB . LEU E 3 158 ? 117.689 -27.687 18.697 1.00 143.45 ? 135 LEU L CB 1 ATOM 7653 C CG . LEU E 3 158 ? 117.778 -27.401 20.194 1.00 142.97 ? 135 LEU L CG 1 ATOM 7654 C CD1 . LEU E 3 158 ? 118.511 -26.088 20.404 1.00 142.95 ? 135 LEU L CD1 1 ATOM 7655 C CD2 . LEU E 3 158 ? 116.381 -27.334 20.795 1.00 142.81 ? 135 LEU L CD2 1 ATOM 7656 N N . ILE E 3 159 ? 115.599 -29.316 16.264 1.00 143.76 ? 136 ILE L N 1 ATOM 7657 C CA . ILE E 3 159 ? 115.344 -29.360 14.827 1.00 142.96 ? 136 ILE L CA 1 ATOM 7658 C C . ILE E 3 159 ? 114.689 -28.051 14.379 1.00 143.26 ? 136 ILE L C 1 ATOM 7659 O O . ILE E 3 159 ? 113.586 -27.713 14.809 1.00 143.06 ? 136 ILE L O 1 ATOM 7660 C CB . ILE E 3 159 ? 114.449 -30.567 14.454 1.00 141.72 ? 136 ILE L CB 1 ATOM 7661 C CG1 . ILE E 3 159 ? 114.157 -30.547 12.956 1.00 141.04 ? 136 ILE L CG1 1 ATOM 7662 C CG2 . ILE E 3 159 ? 113.176 -30.555 15.278 1.00 140.74 ? 136 ILE L CG2 1 ATOM 7663 C CD1 . ILE E 3 159 ? 113.506 -31.804 12.451 1.00 140.99 ? 136 ILE L CD1 1 ATOM 7664 N N . SER E 3 160 ? 115.387 -27.319 13.515 1.00 143.74 ? 137 SER L N 1 ATOM 7665 C CA . SER E 3 160 ? 114.920 -26.027 13.026 1.00 144.34 ? 137 SER L CA 1 ATOM 7666 C C . SER E 3 160 ? 113.691 -26.055 12.118 1.00 145.25 ? 137 SER L C 1 ATOM 7667 O O . SER E 3 160 ? 112.651 -26.596 12.490 1.00 146.09 ? 137 SER L O 1 ATOM 7668 C CB . SER E 3 160 ? 116.065 -25.301 12.316 1.00 144.01 ? 137 SER L CB 1 ATOM 7669 O OG . SER E 3 160 ? 115.681 -23.987 11.951 1.00 143.67 ? 137 SER L OG 1 ATOM 7670 N N . ASP E 3 161 ? 113.821 -25.470 10.929 1.00 145.70 ? 138 ASP L N 1 ATOM 7671 C CA . ASP E 3 161 ? 112.720 -25.372 9.969 1.00 145.77 ? 138 ASP L CA 1 ATOM 7672 C C . ASP E 3 161 ? 112.462 -26.610 9.118 1.00 145.74 ? 138 ASP L C 1 ATOM 7673 O O . ASP E 3 161 ? 113.323 -27.478 8.980 1.00 145.54 ? 138 ASP L O 1 ATOM 7674 C CB . ASP E 3 161 ? 112.962 -24.196 9.026 1.00 146.18 ? 138 ASP L CB 1 ATOM 7675 C CG . ASP E 3 161 ? 113.948 -24.532 7.927 1.00 146.50 ? 138 ASP L CG 1 ATOM 7676 O OD1 . ASP E 3 161 ? 115.127 -24.800 8.243 1.00 146.74 ? 138 ASP L OD1 1 ATOM 7677 O OD2 . ASP E 3 161 ? 113.540 -24.537 6.746 1.00 146.62 ? 138 ASP L OD2 1 ATOM 7678 N N . PHE E 3 162 ? 111.263 -26.659 8.539 1.00 145.84 ? 139 PHE L N 1 ATOM 7679 C CA . PHE E 3 162 ? 110.833 -27.755 7.673 1.00 146.28 ? 139 PHE L CA 1 ATOM 7680 C C . PHE E 3 162 ? 109.349 -27.633 7.312 1.00 146.78 ? 139 PHE L C 1 ATOM 7681 O O . PHE E 3 162 ? 108.485 -27.640 8.187 1.00 147.23 ? 139 PHE L O 1 ATOM 7682 C CB . PHE E 3 162 ? 111.120 -29.110 8.339 1.00 145.94 ? 139 PHE L CB 1 ATOM 7683 C CG . PHE E 3 162 ? 110.464 -29.295 9.683 1.00 145.10 ? 139 PHE L CG 1 ATOM 7684 C CD1 . PHE E 3 162 ? 109.298 -30.043 9.806 1.00 144.83 ? 139 PHE L CD1 1 ATOM 7685 C CD2 . PHE E 3 162 ? 111.029 -28.749 10.830 1.00 144.73 ? 139 PHE L CD2 1 ATOM 7686 C CE1 . PHE E 3 162 ? 108.709 -30.247 11.054 1.00 144.58 ? 139 PHE L CE1 1 ATOM 7687 C CE2 . PHE E 3 162 ? 110.446 -28.946 12.081 1.00 144.36 ? 139 PHE L CE2 1 ATOM 7688 C CZ . PHE E 3 162 ? 109.285 -29.697 12.192 1.00 144.21 ? 139 PHE L CZ 1 ATOM 7689 N N . PHE E 3 163 ? 109.067 -27.515 6.016 1.00 147.08 ? 140 PHE L N 1 ATOM 7690 C CA . PHE E 3 163 ? 107.700 -27.371 5.508 1.00 147.07 ? 140 PHE L CA 1 ATOM 7691 C C . PHE E 3 163 ? 107.352 -28.598 4.667 1.00 146.95 ? 140 PHE L C 1 ATOM 7692 O O . PHE E 3 163 ? 108.026 -28.891 3.685 1.00 146.62 ? 140 PHE L O 1 ATOM 7693 C CB . PHE E 3 163 ? 107.615 -26.097 4.651 1.00 147.64 ? 140 PHE L CB 1 ATOM 7694 C CG . PHE E 3 163 ? 106.210 -25.589 4.414 1.00 148.34 ? 140 PHE L CG 1 ATOM 7695 C CD1 . PHE E 3 163 ? 106.007 -24.286 3.957 1.00 148.40 ? 140 PHE L CD1 1 ATOM 7696 C CD2 . PHE E 3 163 ? 105.097 -26.397 4.634 1.00 148.35 ? 140 PHE L CD2 1 ATOM 7697 C CE1 . PHE E 3 163 ? 104.720 -23.796 3.725 1.00 148.58 ? 140 PHE L CE1 1 ATOM 7698 C CE2 . PHE E 3 163 ? 103.804 -25.918 4.405 1.00 148.48 ? 140 PHE L CE2 1 ATOM 7699 C CZ . PHE E 3 163 ? 103.616 -24.614 3.950 1.00 148.54 ? 140 PHE L CZ 1 ATOM 7700 N N . PRO E 3 164 ? 106.281 -29.322 5.029 1.00 147.34 ? 141 PRO L N 1 ATOM 7701 C CA . PRO E 3 164 ? 105.364 -29.097 6.150 1.00 147.72 ? 141 PRO L CA 1 ATOM 7702 C C . PRO E 3 164 ? 105.947 -29.458 7.510 1.00 148.05 ? 141 PRO L C 1 ATOM 7703 O O . PRO E 3 164 ? 106.954 -30.161 7.602 1.00 147.98 ? 141 PRO L O 1 ATOM 7704 C CB . PRO E 3 164 ? 104.176 -29.976 5.791 1.00 147.54 ? 141 PRO L CB 1 ATOM 7705 C CG . PRO E 3 164 ? 104.851 -31.164 5.193 1.00 147.42 ? 141 PRO L CG 1 ATOM 7706 C CD . PRO E 3 164 ? 105.884 -30.527 4.277 1.00 147.38 ? 141 PRO L CD 1 ATOM 7707 N N . GLY E 3 165 ? 105.292 -28.973 8.561 1.00 148.41 ? 142 GLY L N 1 ATOM 7708 C CA . GLY E 3 165 ? 105.740 -29.245 9.913 1.00 148.73 ? 142 GLY L CA 1 ATOM 7709 C C . GLY E 3 165 ? 105.206 -30.560 10.446 1.00 148.98 ? 142 GLY L C 1 ATOM 7710 O O . GLY E 3 165 ? 104.135 -30.604 11.056 1.00 148.75 ? 142 GLY L O 1 ATOM 7711 N N . ALA E 3 166 ? 105.954 -31.634 10.214 1.00 149.23 ? 143 ALA L N 1 ATOM 7712 C CA . ALA E 3 166 ? 105.556 -32.959 10.672 1.00 149.43 ? 143 ALA L CA 1 ATOM 7713 C C . ALA E 3 166 ? 106.654 -33.981 10.411 1.00 149.29 ? 143 ALA L C 1 ATOM 7714 O O . ALA E 3 166 ? 107.049 -34.205 9.267 1.00 148.95 ? 143 ALA L O 1 ATOM 7715 C CB . ALA E 3 166 ? 104.266 -33.389 9.975 1.00 149.91 ? 143 ALA L CB 1 ATOM 7716 N N . VAL E 3 167 ? 107.143 -34.596 11.483 1.00 149.49 ? 144 VAL L N 1 ATOM 7717 C CA . VAL E 3 167 ? 108.193 -35.603 11.388 1.00 149.95 ? 144 VAL L CA 1 ATOM 7718 C C . VAL E 3 167 ? 108.047 -36.632 12.503 1.00 150.12 ? 144 VAL L C 1 ATOM 7719 O O . VAL E 3 167 ? 107.477 -36.343 13.556 1.00 149.87 ? 144 VAL L O 1 ATOM 7720 C CB . VAL E 3 167 ? 109.600 -34.971 11.499 1.00 149.99 ? 144 VAL L CB 1 ATOM 7721 C CG1 . VAL E 3 167 ? 109.827 -33.994 10.359 1.00 150.33 ? 144 VAL L CG1 1 ATOM 7722 C CG2 . VAL E 3 167 ? 109.750 -34.269 12.837 1.00 149.78 ? 144 VAL L CG2 1 ATOM 7723 N N . THR E 3 168 ? 108.558 -37.834 12.265 1.00 150.43 ? 145 THR L N 1 ATOM 7724 C CA . THR E 3 168 ? 108.493 -38.891 13.264 1.00 150.86 ? 145 THR L CA 1 ATOM 7725 C C . THR E 3 168 ? 109.881 -39.070 13.853 1.00 150.93 ? 145 THR L C 1 ATOM 7726 O O . THR E 3 168 ? 110.541 -40.082 13.619 1.00 150.85 ? 145 THR L O 1 ATOM 7727 C CB . THR E 3 168 ? 108.038 -40.232 12.654 1.00 151.07 ? 145 THR L CB 1 ATOM 7728 O OG1 . THR E 3 168 ? 106.801 -40.049 11.955 1.00 151.52 ? 145 THR L OG1 1 ATOM 7729 C CG2 . THR E 3 168 ? 107.834 -41.271 13.750 1.00 150.97 ? 145 THR L CG2 1 ATOM 7730 N N . VAL E 3 169 ? 110.327 -38.071 14.607 1.00 151.09 ? 146 VAL L N 1 ATOM 7731 C CA . VAL E 3 169 ? 111.640 -38.123 15.230 1.00 151.38 ? 146 VAL L CA 1 ATOM 7732 C C . VAL E 3 169 ? 111.820 -39.477 15.903 1.00 151.47 ? 146 VAL L C 1 ATOM 7733 O O . VAL E 3 169 ? 110.875 -40.030 16.470 1.00 151.42 ? 146 VAL L O 1 ATOM 7734 C CB . VAL E 3 169 ? 111.806 -37.010 16.284 1.00 151.41 ? 146 VAL L CB 1 ATOM 7735 C CG1 . VAL E 3 169 ? 113.167 -37.124 16.957 1.00 151.57 ? 146 VAL L CG1 1 ATOM 7736 C CG2 . VAL E 3 169 ? 111.658 -35.651 15.623 1.00 151.48 ? 146 VAL L CG2 1 ATOM 7737 N N . ALA E 3 170 ? 113.036 -40.009 15.827 1.00 151.43 ? 147 ALA L N 1 ATOM 7738 C CA . ALA E 3 170 ? 113.340 -41.303 16.418 1.00 151.20 ? 147 ALA L CA 1 ATOM 7739 C C . ALA E 3 170 ? 114.584 -41.257 17.298 1.00 150.96 ? 147 ALA L C 1 ATOM 7740 O O . ALA E 3 170 ? 115.620 -40.716 16.909 1.00 150.70 ? 147 ALA L O 1 ATOM 7741 C CB . ALA E 3 170 ? 113.519 -42.347 15.317 1.00 151.12 ? 147 ALA L CB 1 ATOM 7742 N N . TRP E 3 171 ? 114.464 -41.825 18.492 1.00 150.79 ? 148 TRP L N 1 ATOM 7743 C CA . TRP E 3 171 ? 115.572 -41.881 19.431 1.00 150.67 ? 148 TRP L CA 1 ATOM 7744 C C . TRP E 3 171 ? 115.888 -43.337 19.730 1.00 150.67 ? 148 TRP L C 1 ATOM 7745 O O . TRP E 3 171 ? 114.997 -44.125 20.051 1.00 150.58 ? 148 TRP L O 1 ATOM 7746 C CB . TRP E 3 171 ? 115.222 -41.149 20.725 1.00 150.99 ? 148 TRP L CB 1 ATOM 7747 C CG . TRP E 3 171 ? 115.175 -39.667 20.570 1.00 151.21 ? 148 TRP L CG 1 ATOM 7748 C CD1 . TRP E 3 171 ? 114.277 -38.946 19.837 1.00 151.36 ? 148 TRP L CD1 1 ATOM 7749 C CD2 . TRP E 3 171 ? 116.076 -38.718 21.148 1.00 151.06 ? 148 TRP L CD2 1 ATOM 7750 N NE1 . TRP E 3 171 ? 114.564 -37.605 19.923 1.00 151.35 ? 148 TRP L NE1 1 ATOM 7751 C CE2 . TRP E 3 171 ? 115.665 -37.437 20.723 1.00 151.17 ? 148 TRP L CE2 1 ATOM 7752 C CE3 . TRP E 3 171 ? 117.194 -38.824 21.985 1.00 150.82 ? 148 TRP L CE3 1 ATOM 7753 C CZ2 . TRP E 3 171 ? 116.331 -36.270 21.107 1.00 151.17 ? 148 TRP L CZ2 1 ATOM 7754 C CZ3 . TRP E 3 171 ? 117.857 -37.663 22.367 1.00 150.82 ? 148 TRP L CZ3 1 ATOM 7755 C CH2 . TRP E 3 171 ? 117.422 -36.403 21.927 1.00 151.05 ? 148 TRP L CH2 1 ATOM 7756 N N . LYS E 3 172 ? 117.163 -43.687 19.615 1.00 150.49 ? 149 LYS L N 1 ATOM 7757 C CA . LYS E 3 172 ? 117.608 -45.051 19.860 1.00 150.17 ? 149 LYS L CA 1 ATOM 7758 C C . LYS E 3 172 ? 119.050 -45.092 20.352 1.00 149.98 ? 149 LYS L C 1 ATOM 7759 O O . LYS E 3 172 ? 119.852 -44.212 20.033 1.00 149.88 ? 149 LYS L O 1 ATOM 7760 C CB . LYS E 3 172 ? 117.450 -45.878 18.580 1.00 150.01 ? 149 LYS L CB 1 ATOM 7761 C CG . LYS E 3 172 ? 117.802 -45.130 17.301 1.00 149.39 ? 149 LYS L CG 1 ATOM 7762 C CD . LYS E 3 172 ? 117.335 -45.898 16.077 1.00 149.12 ? 149 LYS L CD 1 ATOM 7763 C CE . LYS E 3 172 ? 115.828 -46.118 16.110 1.00 148.85 ? 149 LYS L CE 1 ATOM 7764 N NZ . LYS E 3 172 ? 115.356 -46.942 14.964 1.00 148.99 ? 149 LYS L NZ 1 ATOM 7765 N N . ALA E 3 173 ? 119.368 -46.117 21.137 1.00 149.79 ? 150 ALA L N 1 ATOM 7766 C CA . ALA E 3 173 ? 120.708 -46.278 21.689 1.00 149.58 ? 150 ALA L CA 1 ATOM 7767 C C . ALA E 3 173 ? 121.501 -47.339 20.937 1.00 149.46 ? 150 ALA L C 1 ATOM 7768 O O . ALA E 3 173 ? 121.153 -48.519 20.965 1.00 149.20 ? 150 ALA L O 1 ATOM 7769 C CB . ALA E 3 173 ? 120.620 -46.645 23.164 1.00 149.45 ? 150 ALA L CB 1 ATOM 7770 N N . ASP E 3 174 ? 122.567 -46.906 20.268 1.00 149.38 ? 151 ASP L N 1 ATOM 7771 C CA . ASP E 3 174 ? 123.432 -47.804 19.510 1.00 149.31 ? 151 ASP L CA 1 ATOM 7772 C C . ASP E 3 174 ? 122.744 -48.347 18.256 1.00 149.45 ? 151 ASP L C 1 ATOM 7773 O O . ASP E 3 174 ? 123.136 -48.025 17.133 1.00 148.92 ? 151 ASP L O 1 ATOM 7774 C CB . ASP E 3 174 ? 123.886 -48.963 20.405 1.00 148.67 ? 151 ASP L CB 1 ATOM 7775 C CG . ASP E 3 174 ? 124.532 -48.486 21.697 1.00 148.06 ? 151 ASP L CG 1 ATOM 7776 O OD1 . ASP E 3 174 ? 125.623 -47.884 21.634 1.00 147.59 ? 151 ASP L OD1 1 ATOM 7777 O OD2 . ASP E 3 174 ? 123.944 -48.709 22.776 1.00 147.63 ? 151 ASP L OD2 1 ATOM 7778 N N . GLY E 3 175 ? 121.718 -49.169 18.455 1.00 150.00 ? 152 GLY L N 1 ATOM 7779 C CA . GLY E 3 175 ? 120.997 -49.740 17.331 1.00 150.80 ? 152 GLY L CA 1 ATOM 7780 C C . GLY E 3 175 ? 119.511 -49.926 17.595 1.00 151.26 ? 152 GLY L C 1 ATOM 7781 O O . GLY E 3 175 ? 118.675 -49.536 16.776 1.00 151.18 ? 152 GLY L O 1 ATOM 7782 N N . ALA E 3 176 ? 119.180 -50.524 18.736 1.00 151.43 ? 153 ALA L N 1 ATOM 7783 C CA . ALA E 3 176 ? 117.787 -50.762 19.105 1.00 151.47 ? 153 ALA L CA 1 ATOM 7784 C C . ALA E 3 176 ? 117.186 -49.525 19.766 1.00 151.57 ? 153 ALA L C 1 ATOM 7785 O O . ALA E 3 176 ? 117.784 -48.940 20.670 1.00 151.57 ? 153 ALA L O 1 ATOM 7786 C CB . ALA E 3 176 ? 117.693 -51.955 20.050 1.00 151.49 ? 153 ALA L CB 1 ATOM 7787 N N . PRO E 3 177 ? 115.989 -49.109 19.316 1.00 151.57 ? 154 PRO L N 1 ATOM 7788 C CA . PRO E 3 177 ? 115.298 -47.935 19.863 1.00 151.57 ? 154 PRO L CA 1 ATOM 7789 C C . PRO E 3 177 ? 114.707 -48.166 21.257 1.00 151.57 ? 154 PRO L C 1 ATOM 7790 O O . PRO E 3 177 ? 114.169 -49.238 21.544 1.00 151.33 ? 154 PRO L O 1 ATOM 7791 C CB . PRO E 3 177 ? 114.228 -47.653 18.811 1.00 151.57 ? 154 PRO L CB 1 ATOM 7792 C CG . PRO E 3 177 ? 113.883 -49.027 18.326 1.00 151.57 ? 154 PRO L CG 1 ATOM 7793 C CD . PRO E 3 177 ? 115.245 -49.669 18.172 1.00 151.57 ? 154 PRO L CD 1 ATOM 7794 N N . VAL E 3 178 ? 114.812 -47.153 22.115 1.00 151.57 ? 155 VAL L N 1 ATOM 7795 C CA . VAL E 3 178 ? 114.297 -47.235 23.480 1.00 151.51 ? 155 VAL L CA 1 ATOM 7796 C C . VAL E 3 178 ? 112.827 -46.815 23.572 1.00 151.57 ? 155 VAL L C 1 ATOM 7797 O O . VAL E 3 178 ? 112.361 -45.975 22.796 1.00 151.45 ? 155 VAL L O 1 ATOM 7798 C CB . VAL E 3 178 ? 115.130 -46.352 24.447 1.00 151.27 ? 155 VAL L CB 1 ATOM 7799 C CG1 . VAL E 3 178 ? 116.582 -46.794 24.432 1.00 150.85 ? 155 VAL L CG1 1 ATOM 7800 C CG2 . VAL E 3 178 ? 115.018 -44.888 24.051 1.00 151.30 ? 155 VAL L CG2 1 ATOM 7801 N N . LYS E 3 179 ? 112.109 -47.409 24.524 1.00 151.57 ? 156 LYS L N 1 ATOM 7802 C CA . LYS E 3 179 ? 110.692 -47.118 24.740 1.00 151.56 ? 156 LYS L CA 1 ATOM 7803 C C . LYS E 3 179 ? 110.419 -45.614 24.794 1.00 151.57 ? 156 LYS L C 1 ATOM 7804 O O . LYS E 3 179 ? 110.293 -44.957 23.757 1.00 151.55 ? 156 LYS L O 1 ATOM 7805 C CB . LYS E 3 179 ? 110.199 -47.770 26.045 1.00 151.55 ? 156 LYS L CB 1 ATOM 7806 C CG . LYS E 3 179 ? 110.026 -49.295 26.011 1.00 151.05 ? 156 LYS L CG 1 ATOM 7807 C CD . LYS E 3 179 ? 109.389 -49.800 27.314 1.00 149.89 ? 156 LYS L CD 1 ATOM 7808 C CE . LYS E 3 179 ? 109.002 -51.278 27.256 1.00 148.93 ? 156 LYS L CE 1 ATOM 7809 N NZ . LYS E 3 179 ? 110.172 -52.192 27.188 1.00 148.03 ? 156 LYS L NZ 1 ATOM 7810 N N . ALA E 3 180 ? 110.323 -45.081 26.010 1.00 151.57 ? 157 ALA L N 1 ATOM 7811 C CA . ALA E 3 180 ? 110.061 -43.660 26.216 1.00 151.57 ? 157 ALA L CA 1 ATOM 7812 C C . ALA E 3 180 ? 111.214 -42.974 26.950 1.00 151.55 ? 157 ALA L C 1 ATOM 7813 O O . ALA E 3 180 ? 112.363 -43.424 26.890 1.00 151.57 ? 157 ALA L O 1 ATOM 7814 C CB . ALA E 3 180 ? 108.751 -43.472 26.994 1.00 151.10 ? 157 ALA L CB 1 ATOM 7815 N N . GLY E 3 181 ? 110.895 -41.888 27.649 1.00 151.43 ? 158 GLY L N 1 ATOM 7816 C CA . GLY E 3 181 ? 111.906 -41.135 28.369 1.00 150.68 ? 158 GLY L CA 1 ATOM 7817 C C . GLY E 3 181 ? 112.217 -39.866 27.597 1.00 150.26 ? 158 GLY L C 1 ATOM 7818 O O . GLY E 3 181 ? 112.756 -38.902 28.139 1.00 149.98 ? 158 GLY L O 1 ATOM 7819 N N . VAL E 3 182 ? 111.861 -39.877 26.316 1.00 149.92 ? 159 VAL L N 1 ATOM 7820 C CA . VAL E 3 182 ? 112.079 -38.743 25.425 1.00 149.33 ? 159 VAL L CA 1 ATOM 7821 C C . VAL E 3 182 ? 110.746 -38.063 25.108 1.00 148.35 ? 159 VAL L C 1 ATOM 7822 O O . VAL E 3 182 ? 109.776 -38.725 24.737 1.00 148.06 ? 159 VAL L O 1 ATOM 7823 C CB . VAL E 3 182 ? 112.753 -39.204 24.104 1.00 149.93 ? 159 VAL L CB 1 ATOM 7824 C CG1 . VAL E 3 182 ? 111.965 -40.349 23.482 1.00 149.92 ? 159 VAL L CG1 1 ATOM 7825 C CG2 . VAL E 3 182 ? 112.855 -38.038 23.134 1.00 150.37 ? 159 VAL L CG2 1 ATOM 7826 N N . GLU E 3 183 ? 110.704 -36.741 25.255 1.00 147.31 ? 160 GLU L N 1 ATOM 7827 C CA . GLU E 3 183 ? 109.483 -35.984 24.992 1.00 146.05 ? 160 GLU L CA 1 ATOM 7828 C C . GLU E 3 183 ? 109.654 -34.998 23.840 1.00 145.64 ? 160 GLU L C 1 ATOM 7829 O O . GLU E 3 183 ? 110.603 -34.214 23.819 1.00 145.42 ? 160 GLU L O 1 ATOM 7830 C CB . GLU E 3 183 ? 109.052 -35.232 26.253 1.00 145.05 ? 160 GLU L CB 1 ATOM 7831 C CG . GLU E 3 183 ? 107.617 -34.763 26.203 1.00 143.49 ? 160 GLU L CG 1 ATOM 7832 C CD . GLU E 3 183 ? 106.660 -35.911 25.967 1.00 142.70 ? 160 GLU L CD 1 ATOM 7833 O OE1 . GLU E 3 183 ? 106.615 -36.827 26.815 1.00 142.01 ? 160 GLU L OE1 1 ATOM 7834 O OE2 . GLU E 3 183 ? 105.960 -35.901 24.932 1.00 142.31 ? 160 GLU L OE2 1 ATOM 7835 N N . THR E 3 184 ? 108.724 -35.036 22.889 1.00 145.37 ? 161 THR L N 1 ATOM 7836 C CA . THR E 3 184 ? 108.777 -34.150 21.729 1.00 145.29 ? 161 THR L CA 1 ATOM 7837 C C . THR E 3 184 ? 107.541 -33.262 21.612 1.00 144.97 ? 161 THR L C 1 ATOM 7838 O O . THR E 3 184 ? 106.416 -33.711 21.836 1.00 144.74 ? 161 THR L O 1 ATOM 7839 C CB . THR E 3 184 ? 108.916 -34.954 20.422 1.00 145.41 ? 161 THR L CB 1 ATOM 7840 O OG1 . THR E 3 184 ? 110.064 -35.807 20.505 1.00 145.50 ? 161 THR L OG1 1 ATOM 7841 C CG2 . THR E 3 184 ? 109.074 -34.013 19.234 1.00 145.21 ? 161 THR L CG2 1 ATOM 7842 N N . THR E 3 185 ? 107.761 -32.002 21.246 1.00 144.60 ? 162 THR L N 1 ATOM 7843 C CA . THR E 3 185 ? 106.676 -31.038 21.096 1.00 144.25 ? 162 THR L CA 1 ATOM 7844 C C . THR E 3 185 ? 105.981 -31.147 19.740 1.00 144.11 ? 162 THR L C 1 ATOM 7845 O O . THR E 3 185 ? 105.954 -32.213 19.120 1.00 143.93 ? 162 THR L O 1 ATOM 7846 C CB . THR E 3 185 ? 107.191 -29.588 21.265 1.00 144.02 ? 162 THR L CB 1 ATOM 7847 O OG1 . THR E 3 185 ? 108.233 -29.332 20.314 1.00 143.43 ? 162 THR L OG1 1 ATOM 7848 C CG2 . THR E 3 185 ? 107.727 -29.373 22.670 1.00 143.91 ? 162 THR L CG2 1 ATOM 7849 N N . LYS E 3 186 ? 105.415 -30.030 19.292 1.00 143.80 ? 163 LYS L N 1 ATOM 7850 C CA . LYS E 3 186 ? 104.714 -29.963 18.016 1.00 143.21 ? 163 LYS L CA 1 ATOM 7851 C C . LYS E 3 186 ? 105.358 -28.862 17.174 1.00 142.83 ? 163 LYS L C 1 ATOM 7852 O O . LYS E 3 186 ? 106.119 -28.041 17.688 1.00 143.05 ? 163 LYS L O 1 ATOM 7853 C CB . LYS E 3 186 ? 103.232 -29.639 18.245 1.00 143.33 ? 163 LYS L CB 1 ATOM 7854 C CG . LYS E 3 186 ? 102.922 -28.155 18.476 1.00 143.28 ? 163 LYS L CG 1 ATOM 7855 C CD . LYS E 3 186 ? 103.762 -27.542 19.597 1.00 143.28 ? 163 LYS L CD 1 ATOM 7856 C CE . LYS E 3 186 ? 103.400 -28.101 20.964 1.00 143.24 ? 163 LYS L CE 1 ATOM 7857 N NZ . LYS E 3 186 ? 102.048 -27.662 21.401 1.00 143.12 ? 163 LYS L NZ 1 ATOM 7858 N N . PRO E 3 187 ? 105.069 -28.835 15.866 1.00 142.20 ? 164 PRO L N 1 ATOM 7859 C CA . PRO E 3 187 ? 105.640 -27.812 14.985 1.00 141.97 ? 164 PRO L CA 1 ATOM 7860 C C . PRO E 3 187 ? 105.344 -26.394 15.473 1.00 141.75 ? 164 PRO L C 1 ATOM 7861 O O . PRO E 3 187 ? 104.574 -26.206 16.413 1.00 141.66 ? 164 PRO L O 1 ATOM 7862 C CB . PRO E 3 187 ? 104.982 -28.118 13.646 1.00 141.93 ? 164 PRO L CB 1 ATOM 7863 C CG . PRO E 3 187 ? 104.861 -29.610 13.688 1.00 142.10 ? 164 PRO L CG 1 ATOM 7864 C CD . PRO E 3 187 ? 104.342 -29.852 15.086 1.00 142.01 ? 164 PRO L CD 1 ATOM 7865 N N . SER E 3 188 ? 105.962 -25.405 14.832 1.00 141.70 ? 165 SER L N 1 ATOM 7866 C CA . SER E 3 188 ? 105.772 -24.000 15.193 1.00 141.69 ? 165 SER L CA 1 ATOM 7867 C C . SER E 3 188 ? 106.359 -23.091 14.113 1.00 142.19 ? 165 SER L C 1 ATOM 7868 O O . SER E 3 188 ? 107.578 -23.025 13.948 1.00 142.02 ? 165 SER L O 1 ATOM 7869 C CB . SER E 3 188 ? 106.452 -23.700 16.533 1.00 141.18 ? 165 SER L CB 1 ATOM 7870 O OG . SER E 3 188 ? 105.929 -24.504 17.577 1.00 139.95 ? 165 SER L OG 1 ATOM 7871 N N . LYS E 3 189 ? 105.495 -22.388 13.385 1.00 142.55 ? 166 LYS L N 1 ATOM 7872 C CA . LYS E 3 189 ? 105.948 -21.497 12.321 1.00 143.17 ? 166 LYS L CA 1 ATOM 7873 C C . LYS E 3 189 ? 106.942 -20.455 12.822 1.00 143.80 ? 166 LYS L C 1 ATOM 7874 O O . LYS E 3 189 ? 106.610 -19.625 13.667 1.00 143.82 ? 166 LYS L O 1 ATOM 7875 C CB . LYS E 3 189 ? 104.757 -20.790 11.673 1.00 143.20 ? 166 LYS L CB 1 ATOM 7876 C CG . LYS E 3 189 ? 105.158 -19.790 10.595 1.00 143.46 ? 166 LYS L CG 1 ATOM 7877 C CD . LYS E 3 189 ? 103.947 -19.117 9.964 1.00 143.65 ? 166 LYS L CD 1 ATOM 7878 C CE . LYS E 3 189 ? 103.109 -20.103 9.169 1.00 143.57 ? 166 LYS L CE 1 ATOM 7879 N NZ . LYS E 3 189 ? 103.879 -20.699 8.042 1.00 143.47 ? 166 LYS L NZ 1 ATOM 7880 N N . GLN E 3 190 ? 108.159 -20.501 12.285 1.00 144.81 ? 167 GLN L N 1 ATOM 7881 C CA . GLN E 3 190 ? 109.220 -19.569 12.667 1.00 145.88 ? 167 GLN L CA 1 ATOM 7882 C C . GLN E 3 190 ? 109.122 -18.250 11.904 1.00 146.69 ? 167 GLN L C 1 ATOM 7883 O O . GLN E 3 190 ? 108.082 -17.922 11.327 1.00 147.08 ? 167 GLN L O 1 ATOM 7884 C CB . GLN E 3 190 ? 110.599 -20.183 12.397 1.00 145.58 ? 167 GLN L CB 1 ATOM 7885 C CG . GLN E 3 190 ? 110.880 -21.487 13.121 1.00 145.31 ? 167 GLN L CG 1 ATOM 7886 C CD . GLN E 3 190 ? 112.282 -22.001 12.851 1.00 144.86 ? 167 GLN L CD 1 ATOM 7887 O OE1 . GLN E 3 190 ? 112.669 -22.203 11.700 1.00 144.26 ? 167 GLN L OE1 1 ATOM 7888 N NE2 . GLN E 3 190 ? 113.050 -22.214 13.914 1.00 144.57 ? 167 GLN L NE2 1 ATOM 7889 N N . SER E 3 191 ? 110.222 -17.500 11.911 1.00 147.21 ? 168 SER L N 1 ATOM 7890 C CA . SER E 3 191 ? 110.295 -16.222 11.212 1.00 147.72 ? 168 SER L CA 1 ATOM 7891 C C . SER E 3 191 ? 110.478 -16.518 9.729 1.00 148.06 ? 168 SER L C 1 ATOM 7892 O O . SER E 3 191 ? 110.041 -15.753 8.870 1.00 148.27 ? 168 SER L O 1 ATOM 7893 C CB . SER E 3 191 ? 111.479 -15.398 11.728 1.00 147.59 ? 168 SER L CB 1 ATOM 7894 O OG . SER E 3 191 ? 111.368 -15.153 13.120 1.00 147.50 ? 168 SER L OG 1 ATOM 7895 N N . ASN E 3 192 ? 111.133 -17.639 9.442 1.00 148.44 ? 169 ASN L N 1 ATOM 7896 C CA . ASN E 3 192 ? 111.367 -18.065 8.069 1.00 148.84 ? 169 ASN L CA 1 ATOM 7897 C C . ASN E 3 192 ? 110.055 -18.626 7.547 1.00 148.97 ? 169 ASN L C 1 ATOM 7898 O O . ASN E 3 192 ? 109.971 -19.100 6.414 1.00 149.01 ? 169 ASN L O 1 ATOM 7899 C CB . ASN E 3 192 ? 112.444 -19.152 8.023 1.00 149.35 ? 169 ASN L CB 1 ATOM 7900 C CG . ASN E 3 192 ? 113.783 -18.675 8.557 1.00 149.77 ? 169 ASN L CG 1 ATOM 7901 O OD1 . ASN E 3 192 ? 114.756 -19.430 8.589 1.00 149.82 ? 169 ASN L OD1 1 ATOM 7902 N ND2 . ASN E 3 192 ? 113.839 -17.416 8.979 1.00 149.98 ? 169 ASN L ND2 1 ATOM 7903 N N . ASN E 3 193 ? 109.031 -18.560 8.392 1.00 149.12 ? 170 ASN L N 1 ATOM 7904 C CA . ASN E 3 193 ? 107.710 -19.064 8.051 1.00 149.23 ? 170 ASN L CA 1 ATOM 7905 C C . ASN E 3 193 ? 107.814 -20.550 7.736 1.00 148.97 ? 170 ASN L C 1 ATOM 7906 O O . ASN E 3 193 ? 107.317 -21.031 6.715 1.00 148.85 ? 170 ASN L O 1 ATOM 7907 C CB . ASN E 3 193 ? 107.141 -18.289 6.863 1.00 149.73 ? 170 ASN L CB 1 ATOM 7908 C CG . ASN E 3 193 ? 107.026 -16.801 7.146 1.00 150.22 ? 170 ASN L CG 1 ATOM 7909 O OD1 . ASN E 3 193 ? 106.442 -16.392 8.154 1.00 149.84 ? 170 ASN L OD1 1 ATOM 7910 N ND2 . ASN E 3 193 ? 107.583 -15.983 6.258 1.00 150.39 ? 170 ASN L ND2 1 ATOM 7911 N N . LYS E 3 194 ? 108.483 -21.259 8.640 1.00 148.55 ? 171 LYS L N 1 ATOM 7912 C CA . LYS E 3 194 ? 108.692 -22.696 8.539 1.00 147.80 ? 171 LYS L CA 1 ATOM 7913 C C . LYS E 3 194 ? 108.451 -23.306 9.916 1.00 147.01 ? 171 LYS L C 1 ATOM 7914 O O . LYS E 3 194 ? 109.026 -22.857 10.907 1.00 147.02 ? 171 LYS L O 1 ATOM 7915 C CB . LYS E 3 194 ? 110.126 -22.993 8.099 1.00 148.36 ? 171 LYS L CB 1 ATOM 7916 C CG . LYS E 3 194 ? 110.471 -22.560 6.683 1.00 149.08 ? 171 LYS L CG 1 ATOM 7917 C CD . LYS E 3 194 ? 109.653 -23.329 5.655 1.00 149.84 ? 171 LYS L CD 1 ATOM 7918 C CE . LYS E 3 194 ? 110.210 -23.148 4.250 1.00 149.90 ? 171 LYS L CE 1 ATOM 7919 N NZ . LYS E 3 194 ? 111.591 -23.701 4.137 1.00 149.61 ? 171 LYS L NZ 1 ATOM 7920 N N . TYR E 3 195 ? 107.600 -24.324 9.977 1.00 146.03 ? 172 TYR L N 1 ATOM 7921 C CA . TYR E 3 195 ? 107.296 -24.984 11.243 1.00 145.07 ? 172 TYR L CA 1 ATOM 7922 C C . TYR E 3 195 ? 108.576 -25.554 11.857 1.00 144.45 ? 172 TYR L C 1 ATOM 7923 O O . TYR E 3 195 ? 109.467 -26.011 11.138 1.00 144.41 ? 172 TYR L O 1 ATOM 7924 C CB . TYR E 3 195 ? 106.276 -26.107 11.019 1.00 144.85 ? 172 TYR L CB 1 ATOM 7925 C CG . TYR E 3 195 ? 104.977 -25.650 10.386 1.00 144.96 ? 172 TYR L CG 1 ATOM 7926 C CD1 . TYR E 3 195 ? 104.958 -25.084 9.110 1.00 145.23 ? 172 TYR L CD1 1 ATOM 7927 C CD2 . TYR E 3 195 ? 103.765 -25.786 11.061 1.00 145.20 ? 172 TYR L CD2 1 ATOM 7928 C CE1 . TYR E 3 195 ? 103.762 -24.662 8.521 1.00 145.38 ? 172 TYR L CE1 1 ATOM 7929 C CE2 . TYR E 3 195 ? 102.563 -25.368 10.481 1.00 145.34 ? 172 TYR L CE2 1 ATOM 7930 C CZ . TYR E 3 195 ? 102.569 -24.808 9.211 1.00 145.28 ? 172 TYR L CZ 1 ATOM 7931 O OH . TYR E 3 195 ? 101.385 -24.401 8.633 1.00 144.84 ? 172 TYR L OH 1 ATOM 7932 N N . ALA E 3 196 ? 108.667 -25.518 13.185 1.00 143.51 ? 173 ALA L N 1 ATOM 7933 C CA . ALA E 3 196 ? 109.842 -26.028 13.888 1.00 142.50 ? 173 ALA L CA 1 ATOM 7934 C C . ALA E 3 196 ? 109.446 -26.751 15.170 1.00 141.92 ? 173 ALA L C 1 ATOM 7935 O O . ALA E 3 196 ? 108.331 -26.593 15.661 1.00 142.04 ? 173 ALA L O 1 ATOM 7936 C CB . ALA E 3 196 ? 110.794 -24.882 14.211 1.00 142.10 ? 173 ALA L CB 1 ATOM 7937 N N . ALA E 3 197 ? 110.367 -27.544 15.709 1.00 141.46 ? 174 ALA L N 1 ATOM 7938 C CA . ALA E 3 197 ? 110.109 -28.288 16.937 1.00 141.14 ? 174 ALA L CA 1 ATOM 7939 C C . ALA E 3 197 ? 111.402 -28.590 17.690 1.00 141.11 ? 174 ALA L C 1 ATOM 7940 O O . ALA E 3 197 ? 112.450 -28.005 17.412 1.00 140.91 ? 174 ALA L O 1 ATOM 7941 C CB . ALA E 3 197 ? 109.377 -29.586 16.615 1.00 140.39 ? 174 ALA L CB 1 ATOM 7942 N N . SER E 3 198 ? 111.313 -29.502 18.652 1.00 141.05 ? 175 SER L N 1 ATOM 7943 C CA . SER E 3 198 ? 112.462 -29.902 19.453 1.00 141.03 ? 175 SER L CA 1 ATOM 7944 C C . SER E 3 198 ? 112.068 -31.063 20.356 1.00 141.24 ? 175 SER L C 1 ATOM 7945 O O . SER E 3 198 ? 110.901 -31.203 20.726 1.00 140.86 ? 175 SER L O 1 ATOM 7946 C CB . SER E 3 198 ? 112.964 -28.726 20.298 1.00 140.94 ? 175 SER L CB 1 ATOM 7947 O OG . SER E 3 198 ? 111.961 -28.261 21.183 1.00 141.15 ? 175 SER L OG 1 ATOM 7948 N N . SER E 3 199 ? 113.046 -31.897 20.701 1.00 141.92 ? 176 SER L N 1 ATOM 7949 C CA . SER E 3 199 ? 112.806 -33.058 21.552 1.00 142.47 ? 176 SER L CA 1 ATOM 7950 C C . SER E 3 199 ? 113.876 -33.192 22.632 1.00 142.95 ? 176 SER L C 1 ATOM 7951 O O . SER E 3 199 ? 115.008 -32.740 22.459 1.00 142.96 ? 176 SER L O 1 ATOM 7952 C CB . SER E 3 199 ? 112.772 -34.331 20.702 1.00 142.14 ? 176 SER L CB 1 ATOM 7953 O OG . SER E 3 199 ? 112.496 -35.470 21.497 1.00 141.89 ? 176 SER L OG 1 ATOM 7954 N N . TYR E 3 200 ? 113.507 -33.815 23.747 1.00 143.46 ? 177 TYR L N 1 ATOM 7955 C CA . TYR E 3 200 ? 114.429 -34.004 24.859 1.00 144.05 ? 177 TYR L CA 1 ATOM 7956 C C . TYR E 3 200 ? 114.360 -35.440 25.365 1.00 144.40 ? 177 TYR L C 1 ATOM 7957 O O . TYR E 3 200 ? 113.277 -36.009 25.482 1.00 144.15 ? 177 TYR L O 1 ATOM 7958 C CB . TYR E 3 200 ? 114.083 -33.042 26.000 1.00 144.47 ? 177 TYR L CB 1 ATOM 7959 C CG . TYR E 3 200 ? 113.961 -31.596 25.570 1.00 145.32 ? 177 TYR L CG 1 ATOM 7960 C CD1 . TYR E 3 200 ? 112.873 -31.162 24.810 1.00 145.50 ? 177 TYR L CD1 1 ATOM 7961 C CD2 . TYR E 3 200 ? 114.944 -30.664 25.901 1.00 145.70 ? 177 TYR L CD2 1 ATOM 7962 C CE1 . TYR E 3 200 ? 112.769 -29.836 24.387 1.00 145.80 ? 177 TYR L CE1 1 ATOM 7963 C CE2 . TYR E 3 200 ? 114.851 -29.335 25.483 1.00 145.84 ? 177 TYR L CE2 1 ATOM 7964 C CZ . TYR E 3 200 ? 113.761 -28.928 24.726 1.00 145.95 ? 177 TYR L CZ 1 ATOM 7965 O OH . TYR E 3 200 ? 113.669 -27.621 24.300 1.00 145.92 ? 177 TYR L OH 1 ATOM 7966 N N . LEU E 3 201 ? 115.518 -36.022 25.662 1.00 145.10 ? 178 LEU L N 1 ATOM 7967 C CA . LEU E 3 201 ? 115.580 -37.391 26.161 1.00 145.70 ? 178 LEU L CA 1 ATOM 7968 C C . LEU E 3 201 ? 116.057 -37.425 27.606 1.00 146.53 ? 178 LEU L C 1 ATOM 7969 O O . LEU E 3 201 ? 117.043 -36.777 27.959 1.00 146.23 ? 178 LEU L O 1 ATOM 7970 C CB . LEU E 3 201 ? 116.521 -38.228 25.300 1.00 145.19 ? 178 LEU L CB 1 ATOM 7971 C CG . LEU E 3 201 ? 116.722 -39.668 25.774 1.00 145.24 ? 178 LEU L CG 1 ATOM 7972 C CD1 . LEU E 3 201 ? 115.408 -40.424 25.701 1.00 145.33 ? 178 LEU L CD1 1 ATOM 7973 C CD2 . LEU E 3 201 ? 117.770 -40.346 24.917 1.00 145.45 ? 178 LEU L CD2 1 ATOM 7974 N N . SER E 3 202 ? 115.353 -38.189 28.437 1.00 147.81 ? 179 SER L N 1 ATOM 7975 C CA . SER E 3 202 ? 115.696 -38.312 29.850 1.00 149.26 ? 179 SER L CA 1 ATOM 7976 C C . SER E 3 202 ? 116.751 -39.392 30.067 1.00 150.10 ? 179 SER L C 1 ATOM 7977 O O . SER E 3 202 ? 117.903 -39.235 29.661 1.00 150.55 ? 179 SER L O 1 ATOM 7978 C CB . SER E 3 202 ? 114.447 -38.645 30.674 1.00 149.62 ? 179 SER L CB 1 ATOM 7979 O OG . SER E 3 202 ? 113.467 -37.625 30.572 1.00 150.35 ? 179 SER L OG 1 ATOM 7980 N N . LEU E 3 203 ? 116.348 -40.485 30.710 1.00 150.80 ? 180 LEU L N 1 ATOM 7981 C CA . LEU E 3 203 ? 117.243 -41.604 30.994 1.00 151.30 ? 180 LEU L CA 1 ATOM 7982 C C . LEU E 3 203 ? 118.386 -41.185 31.929 1.00 151.57 ? 180 LEU L C 1 ATOM 7983 O O . LEU E 3 203 ? 119.156 -40.272 31.619 1.00 151.57 ? 180 LEU L O 1 ATOM 7984 C CB . LEU E 3 203 ? 117.801 -42.170 29.682 1.00 151.16 ? 180 LEU L CB 1 ATOM 7985 C CG . LEU E 3 203 ? 116.761 -42.491 28.601 1.00 151.23 ? 180 LEU L CG 1 ATOM 7986 C CD1 . LEU E 3 203 ? 117.452 -43.127 27.405 1.00 151.18 ? 180 LEU L CD1 1 ATOM 7987 C CD2 . LEU E 3 203 ? 115.694 -43.423 29.156 1.00 151.14 ? 180 LEU L CD2 1 ATOM 7988 N N . THR E 3 204 ? 118.481 -41.863 33.074 1.00 151.57 ? 181 THR L N 1 ATOM 7989 C CA . THR E 3 204 ? 119.499 -41.587 34.093 1.00 151.57 ? 181 THR L CA 1 ATOM 7990 C C . THR E 3 204 ? 120.890 -41.256 33.541 1.00 151.57 ? 181 THR L C 1 ATOM 7991 O O . THR E 3 204 ? 121.291 -41.769 32.495 1.00 151.57 ? 181 THR L O 1 ATOM 7992 C CB . THR E 3 204 ? 119.628 -42.776 35.077 1.00 151.20 ? 181 THR L CB 1 ATOM 7993 O OG1 . THR E 3 204 ? 119.875 -43.983 34.346 1.00 150.85 ? 181 THR L OG1 1 ATOM 7994 C CG2 . THR E 3 204 ? 118.353 -42.933 35.892 1.00 150.81 ? 181 THR L CG2 1 ATOM 7995 N N . PRO E 3 205 ? 121.647 -40.392 34.249 1.00 151.57 ? 182 PRO L N 1 ATOM 7996 C CA . PRO E 3 205 ? 122.997 -39.990 33.831 1.00 151.57 ? 182 PRO L CA 1 ATOM 7997 C C . PRO E 3 205 ? 123.962 -41.171 33.780 1.00 151.57 ? 182 PRO L C 1 ATOM 7998 O O . PRO E 3 205 ? 125.043 -41.085 33.190 1.00 151.57 ? 182 PRO L O 1 ATOM 7999 C CB . PRO E 3 205 ? 123.391 -38.958 34.887 1.00 151.33 ? 182 PRO L CB 1 ATOM 8000 C CG . PRO E 3 205 ? 122.684 -39.452 36.108 1.00 151.43 ? 182 PRO L CG 1 ATOM 8001 C CD . PRO E 3 205 ? 121.318 -39.814 35.566 1.00 151.56 ? 182 PRO L CD 1 ATOM 8002 N N . GLU E 3 206 ? 123.552 -42.272 34.406 1.00 151.57 ? 183 GLU L N 1 ATOM 8003 C CA . GLU E 3 206 ? 124.342 -43.497 34.451 1.00 151.57 ? 183 GLU L CA 1 ATOM 8004 C C . GLU E 3 206 ? 124.082 -44.292 33.179 1.00 151.51 ? 183 GLU L C 1 ATOM 8005 O O . GLU E 3 206 ? 124.089 -45.524 33.178 1.00 151.28 ? 183 GLU L O 1 ATOM 8006 C CB . GLU E 3 206 ? 123.947 -44.317 35.680 1.00 151.40 ? 183 GLU L CB 1 ATOM 8007 C CG . GLU E 3 206 ? 124.150 -43.569 36.987 1.00 151.57 ? 183 GLU L CG 1 ATOM 8008 C CD . GLU E 3 206 ? 123.499 -44.257 38.171 1.00 151.57 ? 183 GLU L CD 1 ATOM 8009 O OE1 . GLU E 3 206 ? 122.257 -44.404 38.165 1.00 151.57 ? 183 GLU L OE1 1 ATOM 8010 O OE2 . GLU E 3 206 ? 124.228 -44.645 39.109 1.00 151.57 ? 183 GLU L OE2 1 ATOM 8011 N N . GLN E 3 207 ? 123.846 -43.560 32.097 1.00 151.51 ? 184 GLN L N 1 ATOM 8012 C CA . GLN E 3 207 ? 123.581 -44.155 30.799 1.00 151.57 ? 184 GLN L CA 1 ATOM 8013 C C . GLN E 3 207 ? 124.315 -43.391 29.704 1.00 151.57 ? 184 GLN L C 1 ATOM 8014 O O . GLN E 3 207 ? 124.628 -43.955 28.655 1.00 151.57 ? 184 GLN L O 1 ATOM 8015 C CB . GLN E 3 207 ? 122.077 -44.160 30.520 1.00 151.57 ? 184 GLN L CB 1 ATOM 8016 C CG . GLN E 3 207 ? 121.291 -45.145 31.370 1.00 151.57 ? 184 GLN L CG 1 ATOM 8017 C CD . GLN E 3 207 ? 119.793 -45.025 31.162 1.00 151.57 ? 184 GLN L CD 1 ATOM 8018 O OE1 . GLN E 3 207 ? 119.169 -44.059 31.602 1.00 151.54 ? 184 GLN L OE1 1 ATOM 8019 N NE2 . GLN E 3 207 ? 119.209 -46.005 30.480 1.00 151.57 ? 184 GLN L NE2 1 ATOM 8020 N N . TRP E 3 208 ? 124.589 -42.109 29.943 1.00 151.49 ? 185 TRP L N 1 ATOM 8021 C CA . TRP E 3 208 ? 125.301 -41.305 28.954 1.00 151.57 ? 185 TRP L CA 1 ATOM 8022 C C . TRP E 3 208 ? 126.730 -41.817 28.865 1.00 151.57 ? 185 TRP L C 1 ATOM 8023 O O . TRP E 3 208 ? 127.337 -41.830 27.792 1.00 151.57 ? 185 TRP L O 1 ATOM 8024 C CB . TRP E 3 208 ? 125.315 -39.823 29.341 1.00 151.54 ? 185 TRP L CB 1 ATOM 8025 C CG . TRP E 3 208 ? 125.934 -38.949 28.277 1.00 151.52 ? 185 TRP L CG 1 ATOM 8026 C CD1 . TRP E 3 208 ? 125.534 -38.837 26.973 1.00 151.40 ? 185 TRP L CD1 1 ATOM 8027 C CD2 . TRP E 3 208 ? 127.073 -38.087 28.421 1.00 151.57 ? 185 TRP L CD2 1 ATOM 8028 N NE1 . TRP E 3 208 ? 126.352 -37.961 26.298 1.00 151.25 ? 185 TRP L NE1 1 ATOM 8029 C CE2 . TRP E 3 208 ? 127.303 -37.484 27.162 1.00 151.49 ? 185 TRP L CE2 1 ATOM 8030 C CE3 . TRP E 3 208 ? 127.920 -37.762 29.491 1.00 151.57 ? 185 TRP L CE3 1 ATOM 8031 C CZ2 . TRP E 3 208 ? 128.350 -36.577 26.942 1.00 151.37 ? 185 TRP L CZ2 1 ATOM 8032 C CZ3 . TRP E 3 208 ? 128.963 -36.857 29.271 1.00 151.57 ? 185 TRP L CZ3 1 ATOM 8033 C CH2 . TRP E 3 208 ? 129.165 -36.276 28.005 1.00 151.28 ? 185 TRP L CH2 1 ATOM 8034 N N . LYS E 3 209 ? 127.262 -42.241 30.005 1.00 151.48 ? 186 LYS L N 1 ATOM 8035 C CA . LYS E 3 209 ? 128.615 -42.768 30.058 1.00 151.32 ? 186 LYS L CA 1 ATOM 8036 C C . LYS E 3 209 ? 128.574 -44.289 29.927 1.00 151.51 ? 186 LYS L C 1 ATOM 8037 O O . LYS E 3 209 ? 129.565 -44.913 29.545 1.00 151.57 ? 186 LYS L O 1 ATOM 8038 C CB . LYS E 3 209 ? 129.286 -42.354 31.371 1.00 150.81 ? 186 LYS L CB 1 ATOM 8039 C CG . LYS E 3 209 ? 129.388 -40.847 31.540 1.00 150.22 ? 186 LYS L CG 1 ATOM 8040 C CD . LYS E 3 209 ? 130.121 -40.456 32.809 1.00 149.66 ? 186 LYS L CD 1 ATOM 8041 C CE . LYS E 3 209 ? 130.231 -38.942 32.917 1.00 149.26 ? 186 LYS L CE 1 ATOM 8042 N NZ . LYS E 3 209 ? 130.980 -38.511 34.125 1.00 149.23 ? 186 LYS L NZ 1 ATOM 8043 N N . SER E 3 210 ? 127.418 -44.878 30.228 1.00 151.47 ? 187 SER L N 1 ATOM 8044 C CA . SER E 3 210 ? 127.244 -46.328 30.145 1.00 151.31 ? 187 SER L CA 1 ATOM 8045 C C . SER E 3 210 ? 127.198 -46.812 28.694 1.00 151.35 ? 187 SER L C 1 ATOM 8046 O O . SER E 3 210 ? 127.915 -47.741 28.322 1.00 151.48 ? 187 SER L O 1 ATOM 8047 C CB . SER E 3 210 ? 125.963 -46.748 30.874 1.00 151.11 ? 187 SER L CB 1 ATOM 8048 O OG . SER E 3 210 ? 125.818 -48.158 30.886 1.00 150.41 ? 187 SER L OG 1 ATOM 8049 N N . HIS E 3 211 ? 126.351 -46.185 27.881 1.00 151.13 ? 188 HIS L N 1 ATOM 8050 C CA . HIS E 3 211 ? 126.224 -46.550 26.471 1.00 150.99 ? 188 HIS L CA 1 ATOM 8051 C C . HIS E 3 211 ? 127.034 -45.594 25.589 1.00 150.72 ? 188 HIS L C 1 ATOM 8052 O O . HIS E 3 211 ? 127.564 -44.592 26.072 1.00 150.38 ? 188 HIS L O 1 ATOM 8053 C CB . HIS E 3 211 ? 124.749 -46.529 26.050 1.00 151.09 ? 188 HIS L CB 1 ATOM 8054 C CG . HIS E 3 211 ? 123.936 -47.651 26.624 1.00 151.10 ? 188 HIS L CG 1 ATOM 8055 N ND1 . HIS E 3 211 ? 124.157 -48.972 26.300 1.00 151.14 ? 188 HIS L ND1 1 ATOM 8056 C CD2 . HIS E 3 211 ? 122.897 -47.646 27.492 1.00 151.12 ? 188 HIS L CD2 1 ATOM 8057 C CE1 . HIS E 3 211 ? 123.290 -49.733 26.943 1.00 150.93 ? 188 HIS L CE1 1 ATOM 8058 N NE2 . HIS E 3 211 ? 122.513 -48.953 27.673 1.00 151.08 ? 188 HIS L NE2 1 ATOM 8059 N N . ARG E 3 212 ? 127.132 -45.905 24.298 1.00 150.48 ? 189 ARG L N 1 ATOM 8060 C CA . ARG E 3 212 ? 127.884 -45.064 23.371 1.00 150.29 ? 189 ARG L CA 1 ATOM 8061 C C . ARG E 3 212 ? 127.055 -44.621 22.169 1.00 150.46 ? 189 ARG L C 1 ATOM 8062 O O . ARG E 3 212 ? 126.322 -45.415 21.576 1.00 150.73 ? 189 ARG L O 1 ATOM 8063 C CB . ARG E 3 212 ? 129.135 -45.803 22.882 1.00 150.09 ? 189 ARG L CB 1 ATOM 8064 C CG . ARG E 3 212 ? 130.133 -44.928 22.117 1.00 149.75 ? 189 ARG L CG 1 ATOM 8065 C CD . ARG E 3 212 ? 130.034 -45.075 20.600 1.00 149.18 ? 189 ARG L CD 1 ATOM 8066 N NE . ARG E 3 212 ? 131.036 -45.990 20.052 1.00 148.60 ? 189 ARG L NE 1 ATOM 8067 C CZ . ARG E 3 212 ? 130.986 -47.316 20.150 1.00 148.66 ? 189 ARG L CZ 1 ATOM 8068 N NH1 . ARG E 3 212 ? 129.976 -47.903 20.777 1.00 148.94 ? 189 ARG L NH1 1 ATOM 8069 N NH2 . ARG E 3 212 ? 131.952 -48.056 19.622 1.00 147.96 ? 189 ARG L NH2 1 ATOM 8070 N N . SER E 3 213 ? 127.178 -43.342 21.821 1.00 150.26 ? 190 SER L N 1 ATOM 8071 C CA . SER E 3 213 ? 126.470 -42.757 20.685 1.00 150.10 ? 190 SER L CA 1 ATOM 8072 C C . SER E 3 213 ? 124.946 -42.801 20.766 1.00 150.18 ? 190 SER L C 1 ATOM 8073 O O . SER E 3 213 ? 124.344 -43.868 20.896 1.00 150.17 ? 190 SER L O 1 ATOM 8074 C CB . SER E 3 213 ? 126.920 -43.427 19.384 1.00 149.76 ? 190 SER L CB 1 ATOM 8075 O OG . SER E 3 213 ? 128.287 -43.168 19.122 1.00 149.43 ? 190 SER L OG 1 ATOM 8076 N N . TYR E 3 214 ? 124.335 -41.623 20.677 1.00 150.11 ? 191 TYR L N 1 ATOM 8077 C CA . TYR E 3 214 ? 122.884 -41.484 20.707 1.00 150.11 ? 191 TYR L CA 1 ATOM 8078 C C . TYR E 3 214 ? 122.440 -40.742 19.449 1.00 150.26 ? 191 TYR L C 1 ATOM 8079 O O . TYR E 3 214 ? 122.941 -39.658 19.155 1.00 150.42 ? 191 TYR L O 1 ATOM 8080 C CB . TYR E 3 214 ? 122.447 -40.716 21.957 1.00 149.61 ? 191 TYR L CB 1 ATOM 8081 C CG . TYR E 3 214 ? 122.347 -41.581 23.195 1.00 149.36 ? 191 TYR L CG 1 ATOM 8082 C CD1 . TYR E 3 214 ? 123.139 -41.331 24.316 1.00 149.08 ? 191 TYR L CD1 1 ATOM 8083 C CD2 . TYR E 3 214 ? 121.456 -42.654 23.244 1.00 148.90 ? 191 TYR L CD2 1 ATOM 8084 C CE1 . TYR E 3 214 ? 123.045 -42.131 25.456 1.00 148.72 ? 191 TYR L CE1 1 ATOM 8085 C CE2 . TYR E 3 214 ? 121.354 -43.457 24.376 1.00 148.63 ? 191 TYR L CE2 1 ATOM 8086 C CZ . TYR E 3 214 ? 122.150 -43.192 25.478 1.00 148.71 ? 191 TYR L CZ 1 ATOM 8087 O OH . TYR E 3 214 ? 122.048 -43.991 26.594 1.00 148.67 ? 191 TYR L OH 1 ATOM 8088 N N . SER E 3 215 ? 121.503 -41.327 18.710 1.00 150.34 ? 192 SER L N 1 ATOM 8089 C CA . SER E 3 215 ? 121.025 -40.715 17.474 1.00 150.66 ? 192 SER L CA 1 ATOM 8090 C C . SER E 3 215 ? 119.619 -40.127 17.558 1.00 151.02 ? 192 SER L C 1 ATOM 8091 O O . SER E 3 215 ? 118.757 -40.635 18.280 1.00 151.32 ? 192 SER L O 1 ATOM 8092 C CB . SER E 3 215 ? 121.073 -41.740 16.338 1.00 150.68 ? 192 SER L CB 1 ATOM 8093 O OG . SER E 3 215 ? 120.220 -42.840 16.606 1.00 150.64 ? 192 SER L OG 1 ATOM 8094 N N . CYS E 3 216 ? 119.400 -39.050 16.807 1.00 150.89 ? 193 CYS L N 1 ATOM 8095 C CA . CYS E 3 216 ? 118.102 -38.385 16.758 1.00 150.46 ? 193 CYS L CA 1 ATOM 8096 C C . CYS E 3 216 ? 117.610 -38.357 15.314 1.00 150.21 ? 193 CYS L C 1 ATOM 8097 O O . CYS E 3 216 ? 117.802 -37.374 14.599 1.00 150.25 ? 193 CYS L O 1 ATOM 8098 C CB . CYS E 3 216 ? 118.202 -36.951 17.303 1.00 150.39 ? 193 CYS L CB 1 ATOM 8099 S SG . CYS E 3 216 ? 116.659 -35.981 17.159 1.00 150.13 ? 193 CYS L SG 1 ATOM 8100 N N . GLN E 3 217 ? 116.987 -39.451 14.889 1.00 149.84 ? 194 GLN L N 1 ATOM 8101 C CA . GLN E 3 217 ? 116.462 -39.556 13.534 1.00 149.55 ? 194 GLN L CA 1 ATOM 8102 C C . GLN E 3 217 ? 115.232 -38.669 13.379 1.00 149.55 ? 194 GLN L C 1 ATOM 8103 O O . GLN E 3 217 ? 114.514 -38.411 14.345 1.00 149.52 ? 194 GLN L O 1 ATOM 8104 C CB . GLN E 3 217 ? 116.084 -41.005 13.227 1.00 149.43 ? 194 GLN L CB 1 ATOM 8105 C CG . GLN E 3 217 ? 117.238 -41.981 13.301 1.00 149.16 ? 194 GLN L CG 1 ATOM 8106 C CD . GLN E 3 217 ? 116.802 -43.408 13.042 1.00 149.18 ? 194 GLN L CD 1 ATOM 8107 O OE1 . GLN E 3 217 ? 116.054 -43.991 13.825 1.00 149.07 ? 194 GLN L OE1 1 ATOM 8108 N NE2 . GLN E 3 217 ? 117.265 -43.976 11.935 1.00 149.30 ? 194 GLN L NE2 1 ATOM 8109 N N . VAL E 3 218 ? 114.993 -38.199 12.161 1.00 149.38 ? 195 VAL L N 1 ATOM 8110 C CA . VAL E 3 218 ? 113.845 -37.347 11.883 1.00 149.26 ? 195 VAL L CA 1 ATOM 8111 C C . VAL E 3 218 ? 113.350 -37.620 10.471 1.00 148.92 ? 195 VAL L C 1 ATOM 8112 O O . VAL E 3 218 ? 113.717 -36.917 9.528 1.00 148.67 ? 195 VAL L O 1 ATOM 8113 C CB . VAL E 3 218 ? 114.208 -35.852 11.993 1.00 149.70 ? 195 VAL L CB 1 ATOM 8114 C CG1 . VAL E 3 218 ? 112.987 -35.000 11.690 1.00 149.82 ? 195 VAL L CG1 1 ATOM 8115 C CG2 . VAL E 3 218 ? 114.741 -35.541 13.382 1.00 149.89 ? 195 VAL L CG2 1 ATOM 8116 N N . THR E 3 219 ? 112.518 -38.644 10.325 1.00 148.61 ? 196 THR L N 1 ATOM 8117 C CA . THR E 3 219 ? 111.995 -38.990 9.013 1.00 148.38 ? 196 THR L CA 1 ATOM 8118 C C . THR E 3 219 ? 110.987 -37.951 8.537 1.00 148.36 ? 196 THR L C 1 ATOM 8119 O O . THR E 3 219 ? 109.814 -37.988 8.913 1.00 147.92 ? 196 THR L O 1 ATOM 8120 C CB . THR E 3 219 ? 111.324 -40.384 9.017 1.00 148.07 ? 196 THR L CB 1 ATOM 8121 O OG1 . THR E 3 219 ? 112.264 -41.367 9.469 1.00 147.93 ? 196 THR L OG1 1 ATOM 8122 C CG2 . THR E 3 219 ? 110.866 -40.758 7.613 1.00 147.66 ? 196 THR L CG2 1 ATOM 8123 N N . HIS E 3 220 ? 111.464 -37.016 7.719 1.00 148.37 ? 197 HIS L N 1 ATOM 8124 C CA . HIS E 3 220 ? 110.622 -35.963 7.158 1.00 148.29 ? 197 HIS L CA 1 ATOM 8125 C C . HIS E 3 220 ? 110.191 -36.425 5.766 1.00 148.32 ? 197 HIS L C 1 ATOM 8126 O O . HIS E 3 220 ? 110.707 -35.948 4.753 1.00 148.87 ? 197 HIS L O 1 ATOM 8127 C CB . HIS E 3 220 ? 111.410 -34.648 7.059 1.00 147.90 ? 197 HIS L CB 1 ATOM 8128 C CG . HIS E 3 220 ? 110.579 -33.471 6.640 1.00 147.21 ? 197 HIS L CG 1 ATOM 8129 N ND1 . HIS E 3 220 ? 109.920 -33.414 5.432 1.00 146.92 ? 197 HIS L ND1 1 ATOM 8130 C CD2 . HIS E 3 220 ? 110.300 -32.308 7.274 1.00 146.74 ? 197 HIS L CD2 1 ATOM 8131 C CE1 . HIS E 3 220 ? 109.270 -32.268 5.339 1.00 146.28 ? 197 HIS L CE1 1 ATOM 8132 N NE2 . HIS E 3 220 ? 109.484 -31.578 6.444 1.00 146.21 ? 197 HIS L NE2 1 ATOM 8133 N N . GLU E 3 221 ? 109.249 -37.364 5.727 1.00 147.86 ? 198 GLU L N 1 ATOM 8134 C CA . GLU E 3 221 ? 108.757 -37.910 4.468 1.00 147.31 ? 198 GLU L CA 1 ATOM 8135 C C . GLU E 3 221 ? 109.926 -38.511 3.690 1.00 147.16 ? 198 GLU L C 1 ATOM 8136 O O . GLU E 3 221 ? 110.286 -38.033 2.614 1.00 147.14 ? 198 GLU L O 1 ATOM 8137 C CB . GLU E 3 221 ? 108.079 -36.814 3.638 1.00 147.27 ? 198 GLU L CB 1 ATOM 8138 C CG . GLU E 3 221 ? 106.889 -36.158 4.326 1.00 146.83 ? 198 GLU L CG 1 ATOM 8139 C CD . GLU E 3 221 ? 106.238 -35.085 3.474 1.00 146.55 ? 198 GLU L CD 1 ATOM 8140 O OE1 . GLU E 3 221 ? 105.715 -35.418 2.389 1.00 146.20 ? 198 GLU L OE1 1 ATOM 8141 O OE2 . GLU E 3 221 ? 106.249 -33.907 3.888 1.00 146.41 ? 198 GLU L OE2 1 ATOM 8142 N N . GLY E 3 222 ? 110.520 -39.559 4.253 1.00 147.02 ? 199 GLY L N 1 ATOM 8143 C CA . GLY E 3 222 ? 111.644 -40.211 3.609 1.00 146.71 ? 199 GLY L CA 1 ATOM 8144 C C . GLY E 3 222 ? 112.977 -39.821 4.217 1.00 146.65 ? 199 GLY L C 1 ATOM 8145 O O . GLY E 3 222 ? 113.554 -40.577 5.000 1.00 146.74 ? 199 GLY L O 1 ATOM 8146 N N . SER E 3 223 ? 113.462 -38.635 3.858 1.00 146.57 ? 200 SER L N 1 ATOM 8147 C CA . SER E 3 223 ? 114.740 -38.125 4.350 1.00 146.47 ? 200 SER L CA 1 ATOM 8148 C C . SER E 3 223 ? 114.815 -38.062 5.875 1.00 146.50 ? 200 SER L C 1 ATOM 8149 O O . SER E 3 223 ? 114.204 -37.196 6.502 1.00 146.50 ? 200 SER L O 1 ATOM 8150 C CB . SER E 3 223 ? 114.995 -36.734 3.769 1.00 146.32 ? 200 SER L CB 1 ATOM 8151 O OG . SER E 3 223 ? 114.933 -36.763 2.354 1.00 146.25 ? 200 SER L OG 1 ATOM 8152 N N . THR E 3 224 ? 115.581 -38.978 6.461 1.00 146.59 ? 201 THR L N 1 ATOM 8153 C CA . THR E 3 224 ? 115.742 -39.043 7.912 1.00 146.75 ? 201 THR L CA 1 ATOM 8154 C C . THR E 3 224 ? 117.030 -38.351 8.364 1.00 146.76 ? 201 THR L C 1 ATOM 8155 O O . THR E 3 224 ? 117.864 -38.954 9.041 1.00 146.69 ? 201 THR L O 1 ATOM 8156 C CB . THR E 3 224 ? 115.770 -40.516 8.403 1.00 146.72 ? 201 THR L CB 1 ATOM 8157 O OG1 . THR E 3 224 ? 114.623 -41.215 7.899 1.00 146.75 ? 201 THR L OG1 1 ATOM 8158 C CG2 . THR E 3 224 ? 115.754 -40.577 9.928 1.00 146.38 ? 201 THR L CG2 1 ATOM 8159 N N . VAL E 3 225 ? 117.191 -37.085 7.986 1.00 146.69 ? 202 VAL L N 1 ATOM 8160 C CA . VAL E 3 225 ? 118.379 -36.324 8.364 1.00 146.61 ? 202 VAL L CA 1 ATOM 8161 C C . VAL E 3 225 ? 118.580 -36.453 9.876 1.00 146.60 ? 202 VAL L C 1 ATOM 8162 O O . VAL E 3 225 ? 117.647 -36.225 10.647 1.00 146.60 ? 202 VAL L O 1 ATOM 8163 C CB . VAL E 3 225 ? 118.220 -34.832 7.991 1.00 146.56 ? 202 VAL L CB 1 ATOM 8164 C CG1 . VAL E 3 225 ? 119.522 -34.092 8.244 1.00 146.80 ? 202 VAL L CG1 1 ATOM 8165 C CG2 . VAL E 3 225 ? 117.806 -34.701 6.532 1.00 146.07 ? 202 VAL L CG2 1 ATOM 8166 N N . GLU E 3 226 ? 119.791 -36.818 10.297 1.00 146.68 ? 203 GLU L N 1 ATOM 8167 C CA . GLU E 3 226 ? 120.074 -36.998 11.722 1.00 146.43 ? 203 GLU L CA 1 ATOM 8168 C C . GLU E 3 226 ? 121.507 -36.714 12.185 1.00 145.72 ? 203 GLU L C 1 ATOM 8169 O O . GLU E 3 226 ? 122.441 -36.637 11.386 1.00 144.85 ? 203 GLU L O 1 ATOM 8170 C CB . GLU E 3 226 ? 119.681 -38.418 12.142 1.00 146.95 ? 203 GLU L CB 1 ATOM 8171 C CG . GLU E 3 226 ? 120.302 -39.511 11.285 1.00 147.63 ? 203 GLU L CG 1 ATOM 8172 C CD . GLU E 3 226 ? 119.810 -40.895 11.659 1.00 148.29 ? 203 GLU L CD 1 ATOM 8173 O OE1 . GLU E 3 226 ? 120.073 -41.331 12.800 1.00 148.67 ? 203 GLU L OE1 1 ATOM 8174 O OE2 . GLU E 3 226 ? 119.157 -41.547 10.815 1.00 148.70 ? 203 GLU L OE2 1 ATOM 8175 N N . LYS E 3 227 ? 121.654 -36.569 13.500 1.00 145.39 ? 204 LYS L N 1 ATOM 8176 C CA . LYS E 3 227 ? 122.936 -36.292 14.139 1.00 145.32 ? 204 LYS L CA 1 ATOM 8177 C C . LYS E 3 227 ? 123.140 -37.211 15.345 1.00 145.92 ? 204 LYS L C 1 ATOM 8178 O O . LYS E 3 227 ? 122.176 -37.775 15.870 1.00 145.82 ? 204 LYS L O 1 ATOM 8179 C CB . LYS E 3 227 ? 122.986 -34.832 14.593 1.00 144.57 ? 204 LYS L CB 1 ATOM 8180 C CG . LYS E 3 227 ? 123.096 -33.831 13.459 1.00 143.44 ? 204 LYS L CG 1 ATOM 8181 C CD . LYS E 3 227 ? 124.419 -33.991 12.742 1.00 142.77 ? 204 LYS L CD 1 ATOM 8182 C CE . LYS E 3 227 ? 124.597 -32.940 11.671 1.00 142.33 ? 204 LYS L CE 1 ATOM 8183 N NZ . LYS E 3 227 ? 125.928 -33.074 11.027 1.00 142.37 ? 204 LYS L NZ 1 ATOM 8184 N N . THR E 3 228 ? 124.392 -37.350 15.784 1.00 146.44 ? 205 THR L N 1 ATOM 8185 C CA . THR E 3 228 ? 124.730 -38.207 16.925 1.00 146.65 ? 205 THR L CA 1 ATOM 8186 C C . THR E 3 228 ? 125.754 -37.565 17.869 1.00 147.07 ? 205 THR L C 1 ATOM 8187 O O . THR E 3 228 ? 126.548 -36.716 17.458 1.00 146.98 ? 205 THR L O 1 ATOM 8188 C CB . THR E 3 228 ? 125.292 -39.571 16.449 1.00 146.12 ? 205 THR L CB 1 ATOM 8189 O OG1 . THR E 3 228 ? 124.333 -40.217 15.604 1.00 146.15 ? 205 THR L OG1 1 ATOM 8190 C CG2 . THR E 3 228 ? 125.588 -40.476 17.635 1.00 145.61 ? 205 THR L CG2 1 ATOM 8191 N N . VAL E 3 229 ? 125.726 -37.984 19.135 1.00 147.79 ? 206 VAL L N 1 ATOM 8192 C CA . VAL E 3 229 ? 126.642 -37.474 20.156 1.00 148.48 ? 206 VAL L CA 1 ATOM 8193 C C . VAL E 3 229 ? 127.432 -38.604 20.824 1.00 149.24 ? 206 VAL L C 1 ATOM 8194 O O . VAL E 3 229 ? 126.881 -39.665 21.126 1.00 149.56 ? 206 VAL L O 1 ATOM 8195 C CB . VAL E 3 229 ? 125.880 -36.699 21.254 1.00 148.03 ? 206 VAL L CB 1 ATOM 8196 C CG1 . VAL E 3 229 ? 125.159 -35.516 20.640 1.00 147.78 ? 206 VAL L CG1 1 ATOM 8197 C CG2 . VAL E 3 229 ? 124.897 -37.623 21.965 1.00 147.40 ? 206 VAL L CG2 1 ATOM 8198 N N . ALA E 3 230 ? 128.721 -38.364 21.059 1.00 149.61 ? 207 ALA L N 1 ATOM 8199 C CA . ALA E 3 230 ? 129.598 -39.355 21.683 1.00 149.67 ? 207 ALA L CA 1 ATOM 8200 C C . ALA E 3 230 ? 129.574 -39.275 23.214 1.00 149.75 ? 207 ALA L C 1 ATOM 8201 O O . ALA E 3 230 ? 129.630 -38.185 23.787 1.00 149.69 ? 207 ALA L O 1 ATOM 8202 C CB . ALA E 3 230 ? 131.026 -39.170 21.171 1.00 149.57 ? 207 ALA L CB 1 ATOM 8203 N N . PRO E 3 231 ? 129.504 -40.438 23.894 1.00 149.79 ? 208 PRO L N 1 ATOM 8204 C CA . PRO E 3 231 ? 129.472 -40.530 25.362 1.00 149.37 ? 208 PRO L CA 1 ATOM 8205 C C . PRO E 3 231 ? 130.757 -40.012 25.998 1.00 148.78 ? 208 PRO L C 1 ATOM 8206 O O . PRO E 3 231 ? 131.014 -40.224 27.186 1.00 148.05 ? 208 PRO L O 1 ATOM 8207 C CB . PRO E 3 231 ? 129.271 -42.023 25.605 1.00 149.68 ? 208 PRO L CB 1 ATOM 8208 C CG . PRO E 3 231 ? 130.024 -42.635 24.470 1.00 150.04 ? 208 PRO L CG 1 ATOM 8209 C CD . PRO E 3 231 ? 129.570 -41.785 23.297 1.00 149.95 ? 208 PRO L CD 1 ATOM 8210 N N . THR E 3 232 ? 131.555 -39.333 25.183 1.00 148.61 ? 209 THR L N 1 ATOM 8211 C CA . THR E 3 232 ? 132.824 -38.771 25.612 1.00 148.19 ? 209 THR L CA 1 ATOM 8212 C C . THR E 3 232 ? 133.008 -37.393 24.979 1.00 148.00 ? 209 THR L C 1 ATOM 8213 O O . THR E 3 232 ? 132.977 -36.394 25.729 1.00 147.92 ? 209 THR L O 1 ATOM 8214 C CB . THR E 3 232 ? 133.993 -39.691 25.194 1.00 148.08 ? 209 THR L CB 1 ATOM 8215 O OG1 . THR E 3 232 ? 133.957 -39.901 23.776 1.00 147.64 ? 209 THR L OG1 1 ATOM 8216 C CG2 . THR E 3 232 ? 133.884 -41.039 25.893 1.00 147.75 ? 209 THR L CG2 1 ATOM 8217 N N . GLU E 3 233 ? 133.165 -37.326 23.741 1.00 147.65 ? 210 GLU L N 1 ATOM 8218 N N . GLN F 3 20 ? 88.915 33.971 1.007 1.00 96.48 ? 1 GLN M N 1 ATOM 8219 C CA . GLN F 3 20 ? 87.925 33.865 2.119 1.00 96.13 ? 1 GLN M CA 1 ATOM 8220 C C . GLN F 3 20 ? 86.647 33.124 1.710 1.00 94.81 ? 1 GLN M C 1 ATOM 8221 O O . GLN F 3 20 ? 85.925 32.597 2.559 1.00 94.85 ? 1 GLN M O 1 ATOM 8222 C CB . GLN F 3 20 ? 87.552 35.261 2.632 1.00 97.58 ? 1 GLN M CB 1 ATOM 8223 C CG . GLN F 3 20 ? 86.836 36.137 1.607 1.00 98.35 ? 1 GLN M CG 1 ATOM 8224 C CD . GLN F 3 20 ? 86.285 37.412 2.215 1.00 98.55 ? 1 GLN M CD 1 ATOM 8225 O OE1 . GLN F 3 20 ? 87.018 38.190 2.832 1.00 98.94 ? 1 GLN M OE1 1 ATOM 8226 N NE2 . GLN F 3 20 ? 84.986 37.636 2.042 1.00 98.03 ? 1 GLN M NE2 1 ATOM 8227 N N . SER F 3 21 ? 86.366 33.090 0.412 1.00 92.63 ? 2 SER M N 1 ATOM 8228 C CA . SER F 3 21 ? 85.171 32.423 -0.075 1.00 89.76 ? 2 SER M CA 1 ATOM 8229 C C . SER F 3 21 ? 85.427 31.689 -1.383 1.00 88.19 ? 2 SER M C 1 ATOM 8230 O O . SER F 3 21 ? 84.492 31.397 -2.133 1.00 88.06 ? 2 SER M O 1 ATOM 8231 C CB . SER F 3 21 ? 84.050 33.442 -0.261 1.00 89.69 ? 2 SER M CB 1 ATOM 8232 O OG . SER F 3 21 ? 83.790 34.125 0.951 1.00 89.49 ? 2 SER M OG 1 ATOM 8233 N N . VAL F 3 22 ? 86.693 31.384 -1.651 1.00 85.42 ? 3 VAL M N 1 ATOM 8234 C CA . VAL F 3 22 ? 87.046 30.674 -2.870 1.00 83.79 ? 3 VAL M CA 1 ATOM 8235 C C . VAL F 3 22 ? 88.337 29.886 -2.743 1.00 82.14 ? 3 VAL M C 1 ATOM 8236 O O . VAL F 3 22 ? 89.413 30.456 -2.627 1.00 82.35 ? 3 VAL M O 1 ATOM 8237 C CB . VAL F 3 22 ? 87.162 31.647 -4.058 1.00 84.04 ? 3 VAL M CB 1 ATOM 8238 C CG1 . VAL F 3 22 ? 88.023 32.834 -3.672 1.00 83.10 ? 3 VAL M CG1 1 ATOM 8239 C CG2 . VAL F 3 22 ? 87.743 30.924 -5.266 1.00 84.29 ? 3 VAL M CG2 1 ATOM 8240 N N . LEU F 3 23 ? 88.220 28.565 -2.769 1.00 81.49 ? 4 LEU M N 1 ATOM 8241 C CA . LEU F 3 23 ? 89.377 27.690 -2.665 1.00 82.25 ? 4 LEU M CA 1 ATOM 8242 C C . LEU F 3 23 ? 90.355 27.972 -3.800 1.00 83.92 ? 4 LEU M C 1 ATOM 8243 O O . LEU F 3 23 ? 89.942 28.190 -4.941 1.00 84.99 ? 4 LEU M O 1 ATOM 8244 C CB . LEU F 3 23 ? 88.947 26.226 -2.744 1.00 80.47 ? 4 LEU M CB 1 ATOM 8245 C CG . LEU F 3 23 ? 88.003 25.652 -1.693 1.00 78.69 ? 4 LEU M CG 1 ATOM 8246 C CD1 . LEU F 3 23 ? 86.691 26.394 -1.699 1.00 77.36 ? 4 LEU M CD1 1 ATOM 8247 C CD2 . LEU F 3 23 ? 87.773 24.184 -1.998 1.00 78.86 ? 4 LEU M CD2 1 ATOM 8248 N N . THR F 3 24 ? 91.650 27.952 -3.488 1.00 84.85 ? 5 THR M N 1 ATOM 8249 C CA . THR F 3 24 ? 92.688 28.198 -4.486 1.00 85.22 ? 5 THR M CA 1 ATOM 8250 C C . THR F 3 24 ? 93.732 27.086 -4.516 1.00 85.72 ? 5 THR M C 1 ATOM 8251 O O . THR F 3 24 ? 94.273 26.696 -3.480 1.00 86.33 ? 5 THR M O 1 ATOM 8252 C CB . THR F 3 24 ? 93.424 29.533 -4.226 1.00 85.24 ? 5 THR M CB 1 ATOM 8253 O OG1 . THR F 3 24 ? 92.510 30.629 -4.383 1.00 85.83 ? 5 THR M OG1 1 ATOM 8254 C CG2 . THR F 3 24 ? 94.587 29.698 -5.200 1.00 84.63 ? 5 THR M CG2 1 ATOM 8255 N N . GLN F 3 25 ? 94.006 26.578 -5.712 1.00 86.21 ? 6 GLN M N 1 ATOM 8256 C CA . GLN F 3 25 ? 95.001 25.529 -5.895 1.00 86.62 ? 6 GLN M CA 1 ATOM 8257 C C . GLN F 3 25 ? 95.973 25.908 -7.005 1.00 87.04 ? 6 GLN M C 1 ATOM 8258 O O . GLN F 3 25 ? 95.647 26.693 -7.894 1.00 86.58 ? 6 GLN M O 1 ATOM 8259 C CB . GLN F 3 25 ? 94.330 24.192 -6.219 1.00 86.48 ? 6 GLN M CB 1 ATOM 8260 C CG . GLN F 3 25 ? 92.915 24.311 -6.747 1.00 86.21 ? 6 GLN M CG 1 ATOM 8261 C CD . GLN F 3 25 ? 92.236 22.964 -6.888 1.00 85.40 ? 6 GLN M CD 1 ATOM 8262 O OE1 . GLN F 3 25 ? 91.018 22.887 -7.027 1.00 86.01 ? 6 GLN M OE1 1 ATOM 8263 N NE2 . GLN F 3 25 ? 93.025 21.894 -6.860 1.00 84.81 ? 6 GLN M NE2 1 ATOM 8264 N N . PRO F 3 26 ? 97.192 25.357 -6.961 1.00 87.58 ? 7 PRO M N 1 ATOM 8265 C CA . PRO F 3 26 ? 98.175 25.678 -7.993 1.00 86.98 ? 7 PRO M CA 1 ATOM 8266 C C . PRO F 3 26 ? 97.646 25.273 -9.362 1.00 86.34 ? 7 PRO M C 1 ATOM 8267 O O . PRO F 3 26 ? 97.383 24.096 -9.613 1.00 86.18 ? 7 PRO M O 1 ATOM 8268 C CB . PRO F 3 26 ? 99.392 24.864 -7.565 1.00 87.76 ? 7 PRO M CB 1 ATOM 8269 C CG . PRO F 3 26 ? 98.774 23.650 -6.952 1.00 88.32 ? 7 PRO M CG 1 ATOM 8270 C CD . PRO F 3 26 ? 97.670 24.255 -6.107 1.00 88.27 ? 7 PRO M CD 1 ATOM 8271 N N . PRO F 3 27 ? 97.473 26.251 -10.261 1.00 85.56 ? 8 PRO M N 1 ATOM 8272 C CA . PRO F 3 27 ? 96.969 25.988 -11.611 1.00 85.22 ? 8 PRO M CA 1 ATOM 8273 C C . PRO F 3 27 ? 97.705 24.854 -12.320 1.00 85.46 ? 8 PRO M C 1 ATOM 8274 O O . PRO F 3 27 ? 97.135 24.174 -13.174 1.00 84.21 ? 8 PRO M O 1 ATOM 8275 C CB . PRO F 3 27 ? 97.165 27.328 -12.314 1.00 85.10 ? 8 PRO M CB 1 ATOM 8276 C CG . PRO F 3 27 ? 96.970 28.315 -11.209 1.00 85.05 ? 8 PRO M CG 1 ATOM 8277 C CD . PRO F 3 27 ? 97.736 27.689 -10.067 1.00 85.51 ? 8 PRO M CD 1 ATOM 8278 N N . SER F 3 28 ? 98.964 24.641 -11.947 1.00 86.61 ? 9 SER M N 1 ATOM 8279 C CA . SER F 3 28 ? 99.775 23.607 -12.580 1.00 87.95 ? 9 SER M CA 1 ATOM 8280 C C . SER F 3 28 ? 100.467 22.627 -11.633 1.00 88.55 ? 9 SER M C 1 ATOM 8281 O O . SER F 3 28 ? 100.894 22.985 -10.536 1.00 87.66 ? 9 SER M O 1 ATOM 8282 C CB . SER F 3 28 ? 100.825 24.274 -13.466 1.00 88.54 ? 9 SER M CB 1 ATOM 8283 O OG . SER F 3 28 ? 100.224 25.219 -14.334 1.00 89.04 ? 9 SER M OG 1 ATOM 8284 N N . ALA F 3 29 ? 100.585 21.383 -12.081 1.00 90.15 ? 10 ALA M N 1 ATOM 8285 C CA . ALA F 3 29 ? 101.233 20.345 -11.296 1.00 93.06 ? 10 ALA M CA 1 ATOM 8286 C C . ALA F 3 29 ? 102.096 19.491 -12.216 1.00 94.86 ? 10 ALA M C 1 ATOM 8287 O O . ALA F 3 29 ? 103.044 19.992 -12.818 1.00 96.25 ? 10 ALA M O 1 ATOM 8288 C CB . ALA F 3 29 ? 100.192 19.485 -10.606 1.00 94.30 ? 10 ALA M CB 1 ATOM 8289 N N . SER F 3 30 ? 101.775 18.204 -12.318 1.00 95.95 ? 11 SER M N 1 ATOM 8290 C CA . SER F 3 30 ? 102.522 17.286 -13.179 1.00 97.69 ? 11 SER M CA 1 ATOM 8291 C C . SER F 3 30 ? 103.941 16.960 -12.676 1.00 98.40 ? 11 SER M C 1 ATOM 8292 O O . SER F 3 30 ? 104.698 17.849 -12.270 1.00 97.88 ? 11 SER M O 1 ATOM 8293 C CB . SER F 3 30 ? 102.604 17.860 -14.601 1.00 98.12 ? 11 SER M CB 1 ATOM 8294 O OG . SER F 3 30 ? 101.339 18.314 -15.053 1.00 97.08 ? 11 SER M OG 1 ATOM 8295 N N . GLY F 3 31 ? 104.288 15.676 -12.719 1.00 98.62 ? 12 GLY M N 1 ATOM 8296 C CA . GLY F 3 31 ? 105.598 15.225 -12.280 1.00 99.11 ? 12 GLY M CA 1 ATOM 8297 C C . GLY F 3 31 ? 105.909 13.853 -12.857 1.00 99.98 ? 12 GLY M C 1 ATOM 8298 O O . GLY F 3 31 ? 105.049 13.235 -13.485 1.00 101.22 ? 12 GLY M O 1 ATOM 8299 N N . THR F 3 32 ? 107.130 13.370 -12.642 1.00 99.81 ? 13 THR M N 1 ATOM 8300 C CA . THR F 3 32 ? 107.561 12.065 -13.155 1.00 99.01 ? 13 THR M CA 1 ATOM 8301 C C . THR F 3 32 ? 106.818 10.880 -12.531 1.00 98.37 ? 13 THR M C 1 ATOM 8302 O O . THR F 3 32 ? 106.356 10.954 -11.395 1.00 98.05 ? 13 THR M O 1 ATOM 8303 C CB . THR F 3 32 ? 109.060 11.845 -12.900 1.00 99.33 ? 13 THR M CB 1 ATOM 8304 O OG1 . THR F 3 32 ? 109.285 11.715 -11.490 1.00 99.79 ? 13 THR M OG1 1 ATOM 8305 C CG2 . THR F 3 32 ? 109.871 13.017 -13.433 1.00 99.04 ? 13 THR M CG2 1 ATOM 8306 N N . PRO F 3 33 ? 106.709 9.763 -13.271 1.00 97.82 ? 14 PRO M N 1 ATOM 8307 C CA . PRO F 3 33 ? 106.029 8.552 -12.801 1.00 97.59 ? 14 PRO M CA 1 ATOM 8308 C C . PRO F 3 33 ? 106.779 7.871 -11.663 1.00 97.50 ? 14 PRO M C 1 ATOM 8309 O O . PRO F 3 33 ? 107.911 7.434 -11.829 1.00 97.91 ? 14 PRO M O 1 ATOM 8310 C CB . PRO F 3 33 ? 105.962 7.684 -14.055 1.00 96.88 ? 14 PRO M CB 1 ATOM 8311 C CG . PRO F 3 33 ? 107.176 8.079 -14.792 1.00 97.47 ? 14 PRO M CG 1 ATOM 8312 C CD . PRO F 3 33 ? 107.173 9.584 -14.656 1.00 97.90 ? 14 PRO M CD 1 ATOM 8313 N N . GLY F 3 34 ? 106.127 7.782 -10.511 1.00 97.77 ? 15 GLY M N 1 ATOM 8314 C CA . GLY F 3 34 ? 106.733 7.177 -9.342 1.00 98.17 ? 15 GLY M CA 1 ATOM 8315 C C . GLY F 3 34 ? 106.897 8.263 -8.301 1.00 98.62 ? 15 GLY M C 1 ATOM 8316 O O . GLY F 3 34 ? 106.644 8.062 -7.113 1.00 99.21 ? 15 GLY M O 1 ATOM 8317 N N . GLN F 3 35 ? 107.320 9.431 -8.767 1.00 98.59 ? 16 GLN M N 1 ATOM 8318 C CA . GLN F 3 35 ? 107.519 10.593 -7.912 1.00 98.94 ? 16 GLN M CA 1 ATOM 8319 C C . GLN F 3 35 ? 106.268 10.820 -7.040 1.00 97.52 ? 16 GLN M C 1 ATOM 8320 O O . GLN F 3 35 ? 105.185 10.319 -7.349 1.00 97.46 ? 16 GLN M O 1 ATOM 8321 C CB . GLN F 3 35 ? 107.787 11.816 -8.800 1.00 100.49 ? 16 GLN M CB 1 ATOM 8322 C CG . GLN F 3 35 ? 108.276 13.059 -8.079 1.00 103.57 ? 16 GLN M CG 1 ATOM 8323 C CD . GLN F 3 35 ? 108.327 14.270 -8.998 1.00 105.71 ? 16 GLN M CD 1 ATOM 8324 O OE1 . GLN F 3 35 ? 108.952 14.233 -10.064 1.00 105.96 ? 16 GLN M OE1 1 ATOM 8325 N NE2 . GLN F 3 35 ? 107.663 15.351 -8.591 1.00 106.45 ? 16 GLN M NE2 1 ATOM 8326 N N . ARG F 3 36 ? 106.422 11.555 -5.944 1.00 94.92 ? 17 ARG M N 1 ATOM 8327 C CA . ARG F 3 36 ? 105.295 11.838 -5.066 1.00 92.10 ? 17 ARG M CA 1 ATOM 8328 C C . ARG F 3 36 ? 104.927 13.314 -5.174 1.00 91.80 ? 17 ARG M C 1 ATOM 8329 O O . ARG F 3 36 ? 105.620 14.185 -4.634 1.00 91.39 ? 17 ARG M O 1 ATOM 8330 C CB . ARG F 3 36 ? 105.638 11.471 -3.620 1.00 90.84 ? 17 ARG M CB 1 ATOM 8331 C CG . ARG F 3 36 ? 104.677 12.033 -2.582 1.00 88.88 ? 17 ARG M CG 1 ATOM 8332 C CD . ARG F 3 36 ? 105.336 13.153 -1.777 1.00 87.24 ? 17 ARG M CD 1 ATOM 8333 N NE . ARG F 3 36 ? 104.426 13.783 -0.823 1.00 85.08 ? 17 ARG M NE 1 ATOM 8334 C CZ . ARG F 3 36 ? 103.670 13.120 0.047 1.00 84.69 ? 17 ARG M CZ 1 ATOM 8335 N NH1 . ARG F 3 36 ? 103.703 11.794 0.092 1.00 83.74 ? 17 ARG M NH1 1 ATOM 8336 N NH2 . ARG F 3 36 ? 102.879 13.785 0.879 1.00 83.78 ? 17 ARG M NH2 1 ATOM 8337 N N . VAL F 3 37 ? 103.832 13.578 -5.887 1.00 90.81 ? 18 VAL M N 1 ATOM 8338 C CA . VAL F 3 37 ? 103.330 14.935 -6.106 1.00 88.29 ? 18 VAL M CA 1 ATOM 8339 C C . VAL F 3 37 ? 102.344 15.366 -5.032 1.00 85.90 ? 18 VAL M C 1 ATOM 8340 O O . VAL F 3 37 ? 101.653 14.539 -4.437 1.00 84.50 ? 18 VAL M O 1 ATOM 8341 C CB . VAL F 3 37 ? 102.642 15.054 -7.470 1.00 88.84 ? 18 VAL M CB 1 ATOM 8342 C CG1 . VAL F 3 37 ? 103.688 15.162 -8.572 1.00 89.71 ? 18 VAL M CG1 1 ATOM 8343 C CG2 . VAL F 3 37 ? 101.753 13.839 -7.698 1.00 88.91 ? 18 VAL M CG2 1 ATOM 8344 N N . THR F 3 38 ? 102.281 16.674 -4.809 1.00 83.51 ? 19 THR M N 1 ATOM 8345 C CA . THR F 3 38 ? 101.412 17.245 -3.792 1.00 81.67 ? 19 THR M CA 1 ATOM 8346 C C . THR F 3 38 ? 100.616 18.463 -4.282 1.00 80.78 ? 19 THR M C 1 ATOM 8347 O O . THR F 3 38 ? 101.193 19.497 -4.639 1.00 80.72 ? 19 THR M O 1 ATOM 8348 C CB . THR F 3 38 ? 102.248 17.658 -2.552 1.00 80.53 ? 19 THR M CB 1 ATOM 8349 O OG1 . THR F 3 38 ? 101.403 18.275 -1.577 1.00 79.89 ? 19 THR M OG1 1 ATOM 8350 C CG2 . THR F 3 38 ? 103.339 18.642 -2.949 1.00 80.38 ? 19 THR M CG2 1 ATOM 8351 N N . ILE F 3 39 ? 99.290 18.336 -4.300 1.00 78.79 ? 20 ILE M N 1 ATOM 8352 C CA . ILE F 3 39 ? 98.431 19.442 -4.716 1.00 76.52 ? 20 ILE M CA 1 ATOM 8353 C C . ILE F 3 39 ? 97.812 20.055 -3.478 1.00 75.74 ? 20 ILE M C 1 ATOM 8354 O O . ILE F 3 39 ? 97.356 19.343 -2.588 1.00 74.61 ? 20 ILE M O 1 ATOM 8355 C CB . ILE F 3 39 ? 97.281 18.987 -5.612 1.00 75.38 ? 20 ILE M CB 1 ATOM 8356 C CG1 . ILE F 3 39 ? 97.807 18.090 -6.730 1.00 75.03 ? 20 ILE M CG1 1 ATOM 8357 C CG2 . ILE F 3 39 ? 96.577 20.208 -6.180 1.00 73.73 ? 20 ILE M CG2 1 ATOM 8358 C CD1 . ILE F 3 39 ? 96.722 17.475 -7.579 1.00 74.55 ? 20 ILE M CD1 1 ATOM 8359 N N . SER F 3 40 ? 97.783 21.377 -3.423 1.00 75.83 ? 21 SER M N 1 ATOM 8360 C CA . SER F 3 40 ? 97.214 22.045 -2.268 1.00 77.51 ? 21 SER M CA 1 ATOM 8361 C C . SER F 3 40 ? 95.939 22.831 -2.583 1.00 78.27 ? 21 SER M C 1 ATOM 8362 O O . SER F 3 40 ? 95.636 23.125 -3.742 1.00 78.78 ? 21 SER M O 1 ATOM 8363 C CB . SER F 3 40 ? 98.267 22.950 -1.627 1.00 77.17 ? 21 SER M CB 1 ATOM 8364 O OG . SER F 3 40 ? 98.914 23.735 -2.606 1.00 76.84 ? 21 SER M OG 1 ATOM 8365 N N . CYS F 3 41 ? 95.203 23.163 -1.526 1.00 78.25 ? 22 CYS M N 1 ATOM 8366 C CA . CYS F 3 41 ? 93.936 23.884 -1.610 1.00 78.61 ? 22 CYS M CA 1 ATOM 8367 C C . CYS F 3 41 ? 93.929 24.832 -0.409 1.00 78.99 ? 22 CYS M C 1 ATOM 8368 O O . CYS F 3 41 ? 93.827 24.385 0.733 1.00 80.36 ? 22 CYS M O 1 ATOM 8369 C CB . CYS F 3 41 ? 92.785 22.863 -1.495 1.00 78.21 ? 22 CYS M CB 1 ATOM 8370 S SG . CYS F 3 41 ? 91.084 23.343 -1.983 1.00 75.99 ? 22 CYS M SG 1 ATOM 8371 N N . SER F 3 42 ? 94.047 26.133 -0.646 1.00 79.10 ? 23 SER M N 1 ATOM 8372 C CA . SER F 3 42 ? 94.061 27.075 0.468 1.00 79.64 ? 23 SER M CA 1 ATOM 8373 C C . SER F 3 42 ? 92.816 27.949 0.498 1.00 79.71 ? 23 SER M C 1 ATOM 8374 O O . SER F 3 42 ? 92.273 28.305 -0.548 1.00 79.72 ? 23 SER M O 1 ATOM 8375 C CB . SER F 3 42 ? 95.309 27.960 0.400 1.00 80.26 ? 23 SER M CB 1 ATOM 8376 O OG . SER F 3 42 ? 95.453 28.727 1.586 1.00 81.72 ? 23 SER M OG 1 ATOM 8377 N N . GLY F 3 43 ? 92.367 28.298 1.701 1.00 79.65 ? 24 GLY M N 1 ATOM 8378 C CA . GLY F 3 43 ? 91.182 29.127 1.816 1.00 79.62 ? 24 GLY M CA 1 ATOM 8379 C C . GLY F 3 43 ? 90.996 29.840 3.140 1.00 79.53 ? 24 GLY M C 1 ATOM 8380 O O . GLY F 3 43 ? 91.958 30.172 3.829 1.00 80.34 ? 24 GLY M O 1 ATOM 8381 N N . SER F 3 44 ? 89.738 30.074 3.489 1.00 79.08 ? 25 SER M N 1 ATOM 8382 C CA . SER F 3 44 ? 89.383 30.760 4.721 1.00 79.12 ? 25 SER M CA 1 ATOM 8383 C C . SER F 3 44 ? 88.789 29.820 5.756 1.00 79.74 ? 25 SER M C 1 ATOM 8384 O O . SER F 3 44 ? 88.562 28.642 5.490 1.00 80.30 ? 25 SER M O 1 ATOM 8385 C CB . SER F 3 44 ? 88.367 31.862 4.419 1.00 78.92 ? 25 SER M CB 1 ATOM 8386 O OG . SER F 3 44 ? 87.641 32.243 5.577 1.00 77.82 ? 25 SER M OG 1 ATOM 8387 N N . SER F 3 45 ? 88.543 30.364 6.942 1.00 80.15 ? 26 SER M N 1 ATOM 8388 C CA . SER F 3 45 ? 87.939 29.615 8.034 1.00 80.49 ? 26 SER M CA 1 ATOM 8389 C C . SER F 3 45 ? 86.511 29.313 7.602 1.00 80.23 ? 26 SER M C 1 ATOM 8390 O O . SER F 3 45 ? 86.016 28.194 7.755 1.00 80.54 ? 26 SER M O 1 ATOM 8391 C CB . SER F 3 45 ? 87.885 30.477 9.297 1.00 81.59 ? 26 SER M CB 1 ATOM 8392 O OG . SER F 3 45 ? 86.876 31.476 9.186 1.00 80.87 ? 26 SER M OG 1 ATOM 8393 N N . SER F 3 46 ? 85.865 30.347 7.065 1.00 78.84 ? 27 SER M N 1 ATOM 8394 C CA . SER F 3 46 ? 84.489 30.281 6.590 1.00 76.63 ? 27 SER M CA 1 ATOM 8395 C C . SER F 3 46 ? 84.157 29.028 5.778 1.00 75.51 ? 27 SER M C 1 ATOM 8396 O O . SER F 3 46 ? 82.993 28.641 5.675 1.00 76.54 ? 27 SER M O 1 ATOM 8397 C CB . SER F 3 46 ? 84.178 31.528 5.760 1.00 75.35 ? 27 SER M CB 1 ATOM 8398 O OG . SER F 3 46 ? 82.888 31.449 5.191 1.00 71.88 ? 27 SER M OG 1 ATOM 8399 N N . ASN F 3 47 A 85.165 28.389 5.201 1.00 72.76 ? 27 ASN M N 1 ATOM 8400 C CA . ASN F 3 47 A 84.912 27.193 4.416 1.00 71.15 ? 27 ASN M CA 1 ATOM 8401 C C . ASN F 3 47 A 85.830 26.042 4.781 1.00 69.55 ? 27 ASN M C 1 ATOM 8402 O O . ASN F 3 47 A 85.621 25.388 5.799 1.00 69.41 ? 27 ASN M O 1 ATOM 8403 C CB . ASN F 3 47 A 85.039 27.515 2.936 1.00 71.64 ? 27 ASN M CB 1 ATOM 8404 C CG . ASN F 3 47 A 86.290 28.283 2.626 1.00 72.20 ? 27 ASN M CG 1 ATOM 8405 O OD1 . ASN F 3 47 A 87.401 27.746 2.684 1.00 70.61 ? 27 ASN M OD1 1 ATOM 8406 N ND2 . ASN F 3 47 A 86.125 29.560 2.308 1.00 73.01 ? 27 ASN M ND2 1 ATOM 8407 N N . ILE F 3 48 ? 86.840 25.791 3.954 1.00 68.28 ? 28 ILE M N 1 ATOM 8408 C CA . ILE F 3 48 ? 87.777 24.699 4.210 1.00 68.54 ? 28 ILE M CA 1 ATOM 8409 C C . ILE F 3 48 ? 88.310 24.714 5.639 1.00 66.88 ? 28 ILE M C 1 ATOM 8410 O O . ILE F 3 48 ? 88.855 23.730 6.128 1.00 65.18 ? 28 ILE M O 1 ATOM 8411 C CB . ILE F 3 48 ? 88.970 24.728 3.236 1.00 69.38 ? 28 ILE M CB 1 ATOM 8412 C CG1 . ILE F 3 48 ? 89.901 23.551 3.545 1.00 69.97 ? 28 ILE M CG1 1 ATOM 8413 C CG2 . ILE F 3 48 ? 89.698 26.057 3.343 1.00 69.82 ? 28 ILE M CG2 1 ATOM 8414 C CD1 . ILE F 3 48 ? 90.927 23.279 2.481 1.00 73.12 ? 28 ILE M CD1 1 ATOM 8415 N N . GLY F 3 49 ? 88.158 25.845 6.304 1.00 66.90 ? 29 GLY M N 1 ATOM 8416 C CA . GLY F 3 49 ? 88.604 25.923 7.672 1.00 66.50 ? 29 GLY M CA 1 ATOM 8417 C C . GLY F 3 49 ? 87.628 25.155 8.541 1.00 66.71 ? 29 GLY M C 1 ATOM 8418 O O . GLY F 3 49 ? 88.019 24.233 9.255 1.00 67.64 ? 29 GLY M O 1 ATOM 8419 N N . SER F 3 50 ? 86.348 25.510 8.447 1.00 65.87 ? 30 SER M N 1 ATOM 8420 C CA . SER F 3 50 ? 85.310 24.883 9.261 1.00 64.35 ? 30 SER M CA 1 ATOM 8421 C C . SER F 3 50 ? 84.471 23.729 8.689 1.00 61.95 ? 30 SER M C 1 ATOM 8422 O O . SER F 3 50 ? 83.586 23.233 9.380 1.00 62.09 ? 30 SER M O 1 ATOM 8423 C CB . SER F 3 50 ? 84.358 25.967 9.791 1.00 65.83 ? 30 SER M CB 1 ATOM 8424 O OG . SER F 3 50 ? 83.569 26.533 8.756 1.00 66.14 ? 30 SER M OG 1 ATOM 8425 N N . ASN F 3 51 ? 84.722 23.287 7.463 1.00 58.66 ? 31 ASN M N 1 ATOM 8426 C CA . ASN F 3 51 ? 83.923 22.193 6.924 1.00 56.98 ? 31 ASN M CA 1 ATOM 8427 C C . ASN F 3 51 ? 84.774 21.135 6.247 1.00 56.70 ? 31 ASN M C 1 ATOM 8428 O O . ASN F 3 51 ? 85.903 21.403 5.863 1.00 56.53 ? 31 ASN M O 1 ATOM 8429 C CB . ASN F 3 51 ? 82.892 22.731 5.934 1.00 57.64 ? 31 ASN M CB 1 ATOM 8430 C CG . ASN F 3 51 ? 82.083 23.891 6.498 1.00 57.95 ? 31 ASN M CG 1 ATOM 8431 O OD1 . ASN F 3 51 ? 82.501 25.044 6.425 1.00 58.46 ? 31 ASN M OD1 1 ATOM 8432 N ND2 . ASN F 3 51 ? 80.924 23.586 7.071 1.00 57.21 ? 31 ASN M ND2 1 ATOM 8433 N N . TYR F 3 52 ? 84.240 19.927 6.100 1.00 57.77 ? 32 TYR M N 1 ATOM 8434 C CA . TYR F 3 52 ? 84.995 18.849 5.459 1.00 59.43 ? 32 TYR M CA 1 ATOM 8435 C C . TYR F 3 52 ? 85.495 19.274 4.094 1.00 59.29 ? 32 TYR M C 1 ATOM 8436 O O . TYR F 3 52 ? 85.009 20.253 3.532 1.00 61.49 ? 32 TYR M O 1 ATOM 8437 C CB . TYR F 3 52 ? 84.141 17.603 5.267 1.00 61.29 ? 32 TYR M CB 1 ATOM 8438 C CG . TYR F 3 52 ? 83.809 16.868 6.531 1.00 65.58 ? 32 TYR M CG 1 ATOM 8439 C CD1 . TYR F 3 52 ? 82.701 17.225 7.303 1.00 67.76 ? 32 TYR M CD1 1 ATOM 8440 C CD2 . TYR F 3 52 ? 84.581 15.786 6.941 1.00 66.64 ? 32 TYR M CD2 1 ATOM 8441 C CE1 . TYR F 3 52 ? 82.367 16.508 8.456 1.00 70.18 ? 32 TYR M CE1 1 ATOM 8442 C CE2 . TYR F 3 52 ? 84.264 15.064 8.084 1.00 69.75 ? 32 TYR M CE2 1 ATOM 8443 C CZ . TYR F 3 52 ? 83.155 15.424 8.839 1.00 71.05 ? 32 TYR M CZ 1 ATOM 8444 O OH . TYR F 3 52 ? 82.833 14.681 9.958 1.00 71.87 ? 32 TYR M OH 1 ATOM 8445 N N . VAL F 3 53 ? 86.459 18.535 3.556 1.00 56.60 ? 33 VAL M N 1 ATOM 8446 C CA . VAL F 3 53 ? 86.995 18.852 2.241 1.00 54.23 ? 33 VAL M CA 1 ATOM 8447 C C . VAL F 3 53 ? 86.837 17.638 1.336 1.00 54.48 ? 33 VAL M C 1 ATOM 8448 O O . VAL F 3 53 ? 87.048 16.504 1.763 1.00 56.62 ? 33 VAL M O 1 ATOM 8449 C CB . VAL F 3 53 ? 88.469 19.265 2.330 1.00 52.91 ? 33 VAL M CB 1 ATOM 8450 C CG1 . VAL F 3 53 ? 89.078 19.317 0.949 1.00 53.75 ? 33 VAL M CG1 1 ATOM 8451 C CG2 . VAL F 3 53 ? 88.580 20.621 2.988 1.00 50.82 ? 33 VAL M CG2 1 ATOM 8452 N N . TYR F 3 54 ? 86.448 17.878 0.090 1.00 52.07 ? 34 TYR M N 1 ATOM 8453 C CA . TYR F 3 54 ? 86.226 16.803 -0.866 1.00 51.20 ? 34 TYR M CA 1 ATOM 8454 C C . TYR F 3 54 ? 87.189 16.991 -2.028 1.00 51.91 ? 34 TYR M C 1 ATOM 8455 O O . TYR F 3 54 ? 87.485 18.125 -2.402 1.00 52.10 ? 34 TYR M O 1 ATOM 8456 C CB . TYR F 3 54 ? 84.767 16.853 -1.376 1.00 50.39 ? 34 TYR M CB 1 ATOM 8457 C CG . TYR F 3 54 ? 83.712 16.233 -0.466 1.00 45.78 ? 34 TYR M CG 1 ATOM 8458 C CD1 . TYR F 3 54 ? 83.310 14.908 -0.640 1.00 45.17 ? 34 TYR M CD1 1 ATOM 8459 C CD2 . TYR F 3 54 ? 83.151 16.958 0.589 1.00 44.55 ? 34 TYR M CD2 1 ATOM 8460 C CE1 . TYR F 3 54 ? 82.375 14.311 0.219 1.00 44.99 ? 34 TYR M CE1 1 ATOM 8461 C CE2 . TYR F 3 54 ? 82.219 16.371 1.461 1.00 44.83 ? 34 TYR M CE2 1 ATOM 8462 C CZ . TYR F 3 54 ? 81.834 15.042 1.273 1.00 45.73 ? 34 TYR M CZ 1 ATOM 8463 O OH . TYR F 3 54 ? 80.940 14.431 2.146 1.00 43.08 ? 34 TYR M OH 1 ATOM 8464 N N . TRP F 3 55 ? 87.675 15.889 -2.597 1.00 51.78 ? 35 TRP M N 1 ATOM 8465 C CA . TRP F 3 55 ? 88.606 15.960 -3.717 1.00 53.34 ? 35 TRP M CA 1 ATOM 8466 C C . TRP F 3 55 ? 88.085 15.185 -4.894 1.00 53.50 ? 35 TRP M C 1 ATOM 8467 O O . TRP F 3 55 ? 87.806 13.992 -4.793 1.00 53.09 ? 35 TRP M O 1 ATOM 8468 C CB . TRP F 3 55 ? 89.992 15.415 -3.342 1.00 56.17 ? 35 TRP M CB 1 ATOM 8469 C CG . TRP F 3 55 ? 90.815 16.391 -2.579 1.00 60.00 ? 35 TRP M CG 1 ATOM 8470 C CD1 . TRP F 3 55 ? 90.824 16.577 -1.228 1.00 61.90 ? 35 TRP M CD1 1 ATOM 8471 C CD2 . TRP F 3 55 ? 91.682 17.390 -3.126 1.00 62.96 ? 35 TRP M CD2 1 ATOM 8472 N NE1 . TRP F 3 55 ? 91.639 17.637 -0.895 1.00 62.54 ? 35 TRP M NE1 1 ATOM 8473 C CE2 . TRP F 3 55 ? 92.180 18.153 -2.042 1.00 63.83 ? 35 TRP M CE2 1 ATOM 8474 C CE3 . TRP F 3 55 ? 92.088 17.718 -4.428 1.00 65.15 ? 35 TRP M CE3 1 ATOM 8475 C CZ2 . TRP F 3 55 ? 93.063 19.231 -2.221 1.00 64.82 ? 35 TRP M CZ2 1 ATOM 8476 C CZ3 . TRP F 3 55 ? 92.966 18.791 -4.607 1.00 65.53 ? 35 TRP M CZ3 1 ATOM 8477 C CH2 . TRP F 3 55 ? 93.443 19.533 -3.505 1.00 65.81 ? 35 TRP M CH2 1 ATOM 8478 N N . TYR F 3 56 ? 87.983 15.867 -6.025 1.00 53.31 ? 36 TYR M N 1 ATOM 8479 C CA . TYR F 3 56 ? 87.479 15.238 -7.229 1.00 54.14 ? 36 TYR M CA 1 ATOM 8480 C C . TYR F 3 56 ? 88.527 15.154 -8.343 1.00 55.98 ? 36 TYR M C 1 ATOM 8481 O O . TYR F 3 56 ? 89.262 16.115 -8.614 1.00 57.21 ? 36 TYR M O 1 ATOM 8482 C CB . TYR F 3 56 ? 86.254 16.010 -7.731 1.00 51.14 ? 36 TYR M CB 1 ATOM 8483 C CG . TYR F 3 56 ? 85.131 16.133 -6.733 1.00 47.45 ? 36 TYR M CG 1 ATOM 8484 C CD1 . TYR F 3 56 ? 84.223 15.098 -6.540 1.00 46.74 ? 36 TYR M CD1 1 ATOM 8485 C CD2 . TYR F 3 56 ? 84.965 17.295 -5.997 1.00 46.92 ? 36 TYR M CD2 1 ATOM 8486 C CE1 . TYR F 3 56 ? 83.174 15.226 -5.640 1.00 45.65 ? 36 TYR M CE1 1 ATOM 8487 C CE2 . TYR F 3 56 ? 83.925 17.431 -5.097 1.00 46.37 ? 36 TYR M CE2 1 ATOM 8488 C CZ . TYR F 3 56 ? 83.034 16.398 -4.927 1.00 46.01 ? 36 TYR M CZ 1 ATOM 8489 O OH . TYR F 3 56 ? 81.987 16.565 -4.057 1.00 49.53 ? 36 TYR M OH 1 ATOM 8490 N N . GLN F 3 57 ? 88.578 13.998 -8.993 1.00 55.93 ? 37 GLN M N 1 ATOM 8491 C CA . GLN F 3 57 ? 89.510 13.780 -10.082 1.00 56.89 ? 37 GLN M CA 1 ATOM 8492 C C . GLN F 3 57 ? 88.753 13.690 -11.391 1.00 57.64 ? 37 GLN M C 1 ATOM 8493 O O . GLN F 3 57 ? 87.971 12.760 -11.596 1.00 58.17 ? 37 GLN M O 1 ATOM 8494 C CB . GLN F 3 57 ? 90.277 12.474 -9.889 1.00 57.24 ? 37 GLN M CB 1 ATOM 8495 C CG . GLN F 3 57 ? 91.285 12.218 -10.990 1.00 57.52 ? 37 GLN M CG 1 ATOM 8496 C CD . GLN F 3 57 ? 91.745 10.787 -11.044 1.00 58.93 ? 37 GLN M CD 1 ATOM 8497 O OE1 . GLN F 3 57 ? 90.985 9.891 -11.418 1.00 59.00 ? 37 GLN M OE1 1 ATOM 8498 N NE2 . GLN F 3 57 ? 92.999 10.555 -10.669 1.00 59.71 ? 37 GLN M NE2 1 ATOM 8499 N N . GLN F 3 58 ? 88.997 14.644 -12.283 1.00 57.72 ? 38 GLN M N 1 ATOM 8500 C CA . GLN F 3 58 ? 88.334 14.649 -13.585 1.00 56.68 ? 38 GLN M CA 1 ATOM 8501 C C . GLN F 3 58 ? 89.285 14.253 -14.707 1.00 55.95 ? 38 GLN M C 1 ATOM 8502 O O . GLN F 3 58 ? 90.167 15.027 -15.083 1.00 55.26 ? 38 GLN M O 1 ATOM 8503 C CB . GLN F 3 58 ? 87.759 16.033 -13.881 1.00 54.78 ? 38 GLN M CB 1 ATOM 8504 C CG . GLN F 3 58 ? 87.091 16.127 -15.233 1.00 53.54 ? 38 GLN M CG 1 ATOM 8505 C CD . GLN F 3 58 ? 86.442 17.461 -15.445 1.00 53.85 ? 38 GLN M CD 1 ATOM 8506 O OE1 . GLN F 3 58 ? 87.033 18.502 -15.140 1.00 54.73 ? 38 GLN M OE1 1 ATOM 8507 N NE2 . GLN F 3 58 ? 85.220 17.452 -15.973 1.00 51.85 ? 38 GLN M NE2 1 ATOM 8508 N N . LEU F 3 59 ? 89.111 13.049 -15.237 1.00 55.17 ? 39 LEU M N 1 ATOM 8509 C CA . LEU F 3 59 ? 89.968 12.591 -16.323 1.00 57.44 ? 39 LEU M CA 1 ATOM 8510 C C . LEU F 3 59 ? 89.678 13.418 -17.574 1.00 60.23 ? 39 LEU M C 1 ATOM 8511 O O . LEU F 3 59 ? 88.526 13.536 -17.987 1.00 61.12 ? 39 LEU M O 1 ATOM 8512 C CB . LEU F 3 59 ? 89.718 11.105 -16.615 1.00 54.69 ? 39 LEU M CB 1 ATOM 8513 C CG . LEU F 3 59 ? 90.782 10.074 -16.214 1.00 51.18 ? 39 LEU M CG 1 ATOM 8514 C CD1 . LEU F 3 59 ? 91.131 10.223 -14.748 1.00 49.81 ? 39 LEU M CD1 1 ATOM 8515 C CD2 . LEU F 3 59 ? 90.266 8.664 -16.507 1.00 49.20 ? 39 LEU M CD2 1 ATOM 8516 N N . PRO F 3 60 ? 90.718 14.005 -18.195 1.00 62.88 ? 40 PRO M N 1 ATOM 8517 C CA . PRO F 3 60 ? 90.482 14.804 -19.399 1.00 63.38 ? 40 PRO M CA 1 ATOM 8518 C C . PRO F 3 60 ? 89.463 14.132 -20.315 1.00 63.43 ? 40 PRO M C 1 ATOM 8519 O O . PRO F 3 60 ? 89.659 12.997 -20.761 1.00 63.59 ? 40 PRO M O 1 ATOM 8520 C CB . PRO F 3 60 ? 91.869 14.882 -20.033 1.00 63.56 ? 40 PRO M CB 1 ATOM 8521 C CG . PRO F 3 60 ? 92.757 14.963 -18.845 1.00 64.20 ? 40 PRO M CG 1 ATOM 8522 C CD . PRO F 3 60 ? 92.164 13.884 -17.933 1.00 64.62 ? 40 PRO M CD 1 ATOM 8523 N N . GLY F 3 61 ? 88.365 14.833 -20.567 1.00 63.02 ? 41 GLY M N 1 ATOM 8524 C CA . GLY F 3 61 ? 87.333 14.299 -21.433 1.00 62.67 ? 41 GLY M CA 1 ATOM 8525 C C . GLY F 3 61 ? 86.234 13.541 -20.716 1.00 61.90 ? 41 GLY M C 1 ATOM 8526 O O . GLY F 3 61 ? 85.388 12.922 -21.359 1.00 61.77 ? 41 GLY M O 1 ATOM 8527 N N . THR F 3 62 ? 86.221 13.587 -19.390 1.00 60.35 ? 42 THR M N 1 ATOM 8528 C CA . THR F 3 62 ? 85.198 12.860 -18.666 1.00 59.49 ? 42 THR M CA 1 ATOM 8529 C C . THR F 3 62 ? 84.676 13.531 -17.410 1.00 57.53 ? 42 THR M C 1 ATOM 8530 O O . THR F 3 62 ? 85.221 14.520 -16.922 1.00 57.49 ? 42 THR M O 1 ATOM 8531 C CB . THR F 3 62 ? 85.685 11.447 -18.284 1.00 62.34 ? 42 THR M CB 1 ATOM 8532 O OG1 . THR F 3 62 ? 86.741 11.541 -17.316 1.00 64.14 ? 42 THR M OG1 1 ATOM 8533 C CG2 . THR F 3 62 ? 86.189 10.709 -19.519 1.00 62.69 ? 42 THR M CG2 1 ATOM 8534 N N . ALA F 3 63 ? 83.609 12.945 -16.884 1.00 55.72 ? 43 ALA M N 1 ATOM 8535 C CA . ALA F 3 63 ? 82.937 13.433 -15.694 1.00 52.35 ? 43 ALA M CA 1 ATOM 8536 C C . ALA F 3 63 ? 83.758 13.320 -14.420 1.00 49.05 ? 43 ALA M C 1 ATOM 8537 O O . ALA F 3 63 ? 84.357 12.286 -14.143 1.00 46.51 ? 43 ALA M O 1 ATOM 8538 C CB . ALA F 3 63 ? 81.616 12.687 -15.525 1.00 52.43 ? 43 ALA M CB 1 ATOM 8539 N N . PRO F 3 64 ? 83.789 14.396 -13.624 1.00 47.29 ? 44 PRO M N 1 ATOM 8540 C CA . PRO F 3 64 ? 84.535 14.398 -12.373 1.00 47.82 ? 44 PRO M CA 1 ATOM 8541 C C . PRO F 3 64 ? 84.243 13.115 -11.616 1.00 49.50 ? 44 PRO M C 1 ATOM 8542 O O . PRO F 3 64 ? 83.223 12.470 -11.846 1.00 49.22 ? 44 PRO M O 1 ATOM 8543 C CB . PRO F 3 64 ? 83.985 15.619 -11.651 1.00 46.55 ? 44 PRO M CB 1 ATOM 8544 C CG . PRO F 3 64 ? 83.763 16.557 -12.752 1.00 47.27 ? 44 PRO M CG 1 ATOM 8545 C CD . PRO F 3 64 ? 83.124 15.692 -13.828 1.00 47.20 ? 44 PRO M CD 1 ATOM 8546 N N . LYS F 3 65 ? 85.145 12.744 -10.717 1.00 51.77 ? 45 LYS M N 1 ATOM 8547 C CA . LYS F 3 65 ? 84.974 11.539 -9.922 1.00 52.26 ? 45 LYS M CA 1 ATOM 8548 C C . LYS F 3 65 ? 85.305 11.892 -8.490 1.00 52.45 ? 45 LYS M C 1 ATOM 8549 O O . LYS F 3 65 ? 86.151 12.752 -8.252 1.00 52.74 ? 45 LYS M O 1 ATOM 8550 C CB . LYS F 3 65 ? 85.910 10.438 -10.415 1.00 51.41 ? 45 LYS M CB 1 ATOM 8551 C CG . LYS F 3 65 ? 85.669 9.113 -9.749 1.00 53.61 ? 45 LYS M CG 1 ATOM 8552 C CD . LYS F 3 65 ? 86.494 8.011 -10.374 1.00 55.60 ? 45 LYS M CD 1 ATOM 8553 C CE . LYS F 3 65 ? 86.213 6.684 -9.675 1.00 59.54 ? 45 LYS M CE 1 ATOM 8554 N NZ . LYS F 3 65 ? 87.032 5.542 -10.184 1.00 61.04 ? 45 LYS M NZ 1 ATOM 8555 N N . LEU F 3 66 ? 84.616 11.266 -7.539 1.00 53.48 ? 46 LEU M N 1 ATOM 8556 C CA . LEU F 3 66 ? 84.895 11.529 -6.134 1.00 53.91 ? 46 LEU M CA 1 ATOM 8557 C C . LEU F 3 66 ? 86.134 10.723 -5.776 1.00 55.30 ? 46 LEU M C 1 ATOM 8558 O O . LEU F 3 66 ? 86.189 9.503 -5.983 1.00 54.15 ? 46 LEU M O 1 ATOM 8559 C CB . LEU F 3 66 ? 83.734 11.100 -5.240 1.00 53.18 ? 46 LEU M CB 1 ATOM 8560 C CG . LEU F 3 66 ? 84.047 11.188 -3.741 1.00 52.31 ? 46 LEU M CG 1 ATOM 8561 C CD1 . LEU F 3 66 ? 84.238 12.630 -3.331 1.00 51.06 ? 46 LEU M CD1 1 ATOM 8562 C CD2 . LEU F 3 66 ? 82.919 10.563 -2.949 1.00 53.44 ? 46 LEU M CD2 1 ATOM 8563 N N . LEU F 3 67 ? 87.131 11.419 -5.250 1.00 56.41 ? 47 LEU M N 1 ATOM 8564 C CA . LEU F 3 67 ? 88.384 10.793 -4.874 1.00 58.57 ? 47 LEU M CA 1 ATOM 8565 C C . LEU F 3 67 ? 88.483 10.742 -3.350 1.00 60.42 ? 47 LEU M C 1 ATOM 8566 O O . LEU F 3 67 ? 88.572 9.662 -2.751 1.00 60.02 ? 47 LEU M O 1 ATOM 8567 C CB . LEU F 3 67 ? 89.540 11.611 -5.447 1.00 58.18 ? 47 LEU M CB 1 ATOM 8568 C CG . LEU F 3 67 ? 90.847 10.891 -5.746 1.00 56.34 ? 47 LEU M CG 1 ATOM 8569 C CD1 . LEU F 3 67 ? 90.589 9.786 -6.750 1.00 54.75 ? 47 LEU M CD1 1 ATOM 8570 C CD2 . LEU F 3 67 ? 91.856 11.889 -6.286 1.00 55.54 ? 47 LEU M CD2 1 ATOM 8571 N N . ILE F 3 68 ? 88.449 11.920 -2.732 1.00 61.01 ? 48 ILE M N 1 ATOM 8572 C CA . ILE F 3 68 ? 88.546 12.023 -1.287 1.00 62.45 ? 48 ILE M CA 1 ATOM 8573 C C . ILE F 3 68 ? 87.355 12.746 -0.669 1.00 62.22 ? 48 ILE M C 1 ATOM 8574 O O . ILE F 3 68 ? 86.989 13.850 -1.086 1.00 62.45 ? 48 ILE M O 1 ATOM 8575 C CB . ILE F 3 68 ? 89.832 12.770 -0.887 1.00 65.17 ? 48 ILE M CB 1 ATOM 8576 C CG1 . ILE F 3 68 ? 91.033 12.143 -1.594 1.00 67.48 ? 48 ILE M CG1 1 ATOM 8577 C CG2 . ILE F 3 68 ? 90.028 12.711 0.616 1.00 65.73 ? 48 ILE M CG2 1 ATOM 8578 C CD1 . ILE F 3 68 ? 91.186 10.648 -1.347 1.00 69.03 ? 48 ILE M CD1 1 ATOM 8579 N N . TYR F 3 69 ? 86.758 12.121 0.338 1.00 61.40 ? 49 TYR M N 1 ATOM 8580 C CA . TYR F 3 69 ? 85.618 12.710 1.020 1.00 60.59 ? 49 TYR M CA 1 ATOM 8581 C C . TYR F 3 69 ? 85.853 12.784 2.516 1.00 62.41 ? 49 TYR M C 1 ATOM 8582 O O . TYR F 3 69 ? 86.597 11.981 3.083 1.00 62.87 ? 49 TYR M O 1 ATOM 8583 C CB . TYR F 3 69 ? 84.368 11.899 0.732 1.00 56.87 ? 49 TYR M CB 1 ATOM 8584 C CG . TYR F 3 69 ? 84.359 10.504 1.302 1.00 52.79 ? 49 TYR M CG 1 ATOM 8585 C CD1 . TYR F 3 69 ? 83.929 10.265 2.600 1.00 51.07 ? 49 TYR M CD1 1 ATOM 8586 C CD2 . TYR F 3 69 ? 84.680 9.411 0.504 1.00 52.03 ? 49 TYR M CD2 1 ATOM 8587 C CE1 . TYR F 3 69 ? 83.803 8.972 3.078 1.00 50.70 ? 49 TYR M CE1 1 ATOM 8588 C CE2 . TYR F 3 69 ? 84.561 8.118 0.972 1.00 49.35 ? 49 TYR M CE2 1 ATOM 8589 C CZ . TYR F 3 69 ? 84.118 7.904 2.253 1.00 49.88 ? 49 TYR M CZ 1 ATOM 8590 O OH . TYR F 3 69 ? 83.960 6.617 2.699 1.00 52.26 ? 49 TYR M OH 1 ATOM 8591 N N . ARG F 3 70 ? 85.207 13.744 3.162 1.00 63.38 ? 50 ARG M N 1 ATOM 8592 C CA . ARG F 3 70 ? 85.384 13.919 4.596 1.00 64.23 ? 50 ARG M CA 1 ATOM 8593 C C . ARG F 3 70 ? 86.874 14.044 4.919 1.00 64.05 ? 50 ARG M C 1 ATOM 8594 O O . ARG F 3 70 ? 87.435 13.203 5.621 1.00 65.20 ? 50 ARG M O 1 ATOM 8595 C CB . ARG F 3 70 ? 84.783 12.737 5.375 1.00 64.16 ? 50 ARG M CB 1 ATOM 8596 C CG . ARG F 3 70 ? 83.304 12.892 5.737 1.00 63.99 ? 50 ARG M CG 1 ATOM 8597 C CD . ARG F 3 70 ? 82.896 12.002 6.932 1.00 63.89 ? 50 ARG M CD 1 ATOM 8598 N NE . ARG F 3 70 ? 82.193 10.779 6.542 1.00 63.07 ? 50 ARG M NE 1 ATOM 8599 C CZ . ARG F 3 70 ? 82.745 9.571 6.479 1.00 63.63 ? 50 ARG M CZ 1 ATOM 8600 N NH1 . ARG F 3 70 ? 84.022 9.403 6.788 1.00 64.57 ? 50 ARG M NH1 1 ATOM 8601 N NH2 . ARG F 3 70 ? 82.021 8.526 6.095 1.00 63.78 ? 50 ARG M NH2 1 ATOM 8602 N N . ASN F 3 71 ? 87.509 15.085 4.384 1.00 62.39 ? 51 ASN M N 1 ATOM 8603 C CA . ASN F 3 71 ? 88.928 15.336 4.617 1.00 61.27 ? 51 ASN M CA 1 ATOM 8604 C C . ASN F 3 71 ? 89.940 14.320 4.072 1.00 60.40 ? 51 ASN M C 1 ATOM 8605 O O . ASN F 3 71 ? 90.863 14.701 3.361 1.00 59.38 ? 51 ASN M O 1 ATOM 8606 C CB . ASN F 3 71 ? 89.177 15.535 6.109 1.00 61.26 ? 51 ASN M CB 1 ATOM 8607 C CG . ASN F 3 71 ? 88.639 16.854 6.609 1.00 63.47 ? 51 ASN M CG 1 ATOM 8608 O OD1 . ASN F 3 71 ? 88.957 17.907 6.064 1.00 64.42 ? 51 ASN M OD1 1 ATOM 8609 N ND2 . ASN F 3 71 ? 87.822 16.808 7.654 1.00 65.71 ? 51 ASN M ND2 1 ATOM 8610 N N . ASN F 3 72 ? 89.782 13.037 4.387 1.00 60.59 ? 52 ASN M N 1 ATOM 8611 C CA . ASN F 3 72 ? 90.747 12.041 3.918 1.00 60.39 ? 52 ASN M CA 1 ATOM 8612 C C . ASN F 3 72 ? 90.260 10.604 3.812 1.00 59.71 ? 52 ASN M C 1 ATOM 8613 O O . ASN F 3 72 ? 90.975 9.683 4.175 1.00 56.94 ? 52 ASN M O 1 ATOM 8614 C CB . ASN F 3 72 ? 91.965 12.072 4.823 1.00 62.56 ? 52 ASN M CB 1 ATOM 8615 C CG . ASN F 3 72 ? 91.593 11.965 6.296 1.00 65.45 ? 52 ASN M CG 1 ATOM 8616 O OD1 . ASN F 3 72 ? 91.049 10.946 6.741 1.00 63.37 ? 52 ASN M OD1 1 ATOM 8617 N ND2 . ASN F 3 72 ? 91.879 13.024 7.062 1.00 65.58 ? 52 ASN M ND2 1 ATOM 8618 N N . GLN F 3 73 ? 89.050 10.417 3.300 1.00 61.53 ? 53 GLN M N 1 ATOM 8619 C CA . GLN F 3 73 ? 88.474 9.090 3.125 1.00 63.66 ? 53 GLN M CA 1 ATOM 8620 C C . GLN F 3 73 ? 88.448 8.749 1.639 1.00 65.48 ? 53 GLN M C 1 ATOM 8621 O O . GLN F 3 73 ? 88.183 9.616 0.803 1.00 66.26 ? 53 GLN M O 1 ATOM 8622 C CB . GLN F 3 73 ? 87.051 9.073 3.658 1.00 64.46 ? 53 GLN M CB 1 ATOM 8623 C CG . GLN F 3 73 ? 86.890 9.745 4.996 1.00 64.49 ? 53 GLN M CG 1 ATOM 8624 C CD . GLN F 3 73 ? 87.754 9.117 6.055 1.00 63.91 ? 53 GLN M CD 1 ATOM 8625 O OE1 . GLN F 3 73 ? 87.677 7.910 6.308 1.00 61.72 ? 53 GLN M OE1 1 ATOM 8626 N NE2 . GLN F 3 73 ? 88.587 9.933 6.688 1.00 64.43 ? 53 GLN M NE2 1 ATOM 8627 N N . ARG F 3 74 ? 88.698 7.489 1.304 1.00 67.10 ? 54 ARG M N 1 ATOM 8628 C CA . ARG F 3 74 ? 88.714 7.092 -0.099 1.00 70.03 ? 54 ARG M CA 1 ATOM 8629 C C . ARG F 3 74 ? 87.630 6.074 -0.432 1.00 70.36 ? 54 ARG M C 1 ATOM 8630 O O . ARG F 3 74 ? 87.575 4.996 0.157 1.00 70.51 ? 54 ARG M O 1 ATOM 8631 C CB . ARG F 3 74 ? 90.089 6.518 -0.460 1.00 72.96 ? 54 ARG M CB 1 ATOM 8632 C CG . ARG F 3 74 ? 91.278 7.303 0.110 1.00 75.23 ? 54 ARG M CG 1 ATOM 8633 C CD . ARG F 3 74 ? 92.594 6.630 -0.248 1.00 78.12 ? 54 ARG M CD 1 ATOM 8634 N NE . ARG F 3 74 ? 92.495 5.175 -0.146 1.00 79.69 ? 54 ARG M NE 1 ATOM 8635 C CZ . ARG F 3 74 ? 92.265 4.510 0.983 1.00 79.80 ? 54 ARG M CZ 1 ATOM 8636 N NH1 . ARG F 3 74 ? 92.117 5.162 2.132 1.00 79.95 ? 54 ARG M NH1 1 ATOM 8637 N NH2 . ARG F 3 74 ? 92.155 3.189 0.957 1.00 80.14 ? 54 ARG M NH2 1 ATOM 8638 N N . PRO F 3 75 ? 86.754 6.398 -1.394 1.00 71.00 ? 55 PRO M N 1 ATOM 8639 C CA . PRO F 3 75 ? 85.690 5.456 -1.753 1.00 72.01 ? 55 PRO M CA 1 ATOM 8640 C C . PRO F 3 75 ? 86.192 4.166 -2.405 1.00 73.20 ? 55 PRO M C 1 ATOM 8641 O O . PRO F 3 75 ? 87.336 4.079 -2.848 1.00 71.24 ? 55 PRO M O 1 ATOM 8642 C CB . PRO F 3 75 ? 84.793 6.284 -2.677 1.00 70.48 ? 55 PRO M CB 1 ATOM 8643 C CG . PRO F 3 75 ? 85.749 7.228 -3.313 1.00 69.96 ? 55 PRO M CG 1 ATOM 8644 C CD . PRO F 3 75 ? 86.644 7.644 -2.171 1.00 69.57 ? 55 PRO M CD 1 ATOM 8645 N N . SER F 3 76 ? 85.323 3.162 -2.445 1.00 76.48 ? 56 SER M N 1 ATOM 8646 C CA . SER F 3 76 ? 85.660 1.880 -3.047 1.00 80.10 ? 56 SER M CA 1 ATOM 8647 C C . SER F 3 76 ? 85.973 2.069 -4.520 1.00 82.28 ? 56 SER M C 1 ATOM 8648 O O . SER F 3 76 ? 85.238 2.746 -5.238 1.00 82.40 ? 56 SER M O 1 ATOM 8649 C CB . SER F 3 76 ? 84.501 0.895 -2.893 1.00 80.58 ? 56 SER M CB 1 ATOM 8650 O OG . SER F 3 76 ? 84.298 0.570 -1.529 1.00 83.21 ? 56 SER M OG 1 ATOM 8651 N N . GLY F 3 77 ? 87.063 1.456 -4.968 1.00 84.67 ? 57 GLY M N 1 ATOM 8652 C CA . GLY F 3 77 ? 87.466 1.592 -6.351 1.00 86.80 ? 57 GLY M CA 1 ATOM 8653 C C . GLY F 3 77 ? 88.395 2.787 -6.435 1.00 89.05 ? 57 GLY M C 1 ATOM 8654 O O . GLY F 3 77 ? 88.311 3.595 -7.363 1.00 89.68 ? 57 GLY M O 1 ATOM 8655 N N . VAL F 3 78 ? 89.274 2.909 -5.445 1.00 89.75 ? 58 VAL M N 1 ATOM 8656 C CA . VAL F 3 78 ? 90.222 4.009 -5.411 1.00 91.49 ? 58 VAL M CA 1 ATOM 8657 C C . VAL F 3 78 ? 91.589 3.534 -4.934 1.00 93.43 ? 58 VAL M C 1 ATOM 8658 O O . VAL F 3 78 ? 91.706 2.919 -3.875 1.00 93.52 ? 58 VAL M O 1 ATOM 8659 C CB . VAL F 3 78 ? 89.725 5.151 -4.484 1.00 90.98 ? 58 VAL M CB 1 ATOM 8660 C CG1 . VAL F 3 78 ? 90.799 6.212 -4.317 1.00 89.43 ? 58 VAL M CG1 1 ATOM 8661 C CG2 . VAL F 3 78 ? 88.484 5.779 -5.072 1.00 90.70 ? 58 VAL M CG2 1 ATOM 8662 N N . PRO F 3 79 ? 92.640 3.801 -5.730 1.00 95.09 ? 59 PRO M N 1 ATOM 8663 C CA . PRO F 3 79 ? 94.018 3.420 -5.418 1.00 95.32 ? 59 PRO M CA 1 ATOM 8664 C C . PRO F 3 79 ? 94.419 3.849 -4.019 1.00 95.49 ? 59 PRO M C 1 ATOM 8665 O O . PRO F 3 79 ? 93.888 4.817 -3.468 1.00 95.32 ? 59 PRO M O 1 ATOM 8666 C CB . PRO F 3 79 ? 94.822 4.143 -6.489 1.00 95.44 ? 59 PRO M CB 1 ATOM 8667 C CG . PRO F 3 79 ? 93.924 4.057 -7.663 1.00 96.10 ? 59 PRO M CG 1 ATOM 8668 C CD . PRO F 3 79 ? 92.571 4.414 -7.070 1.00 96.17 ? 59 PRO M CD 1 ATOM 8669 N N . ASP F 3 80 ? 95.377 3.122 -3.461 1.00 95.78 ? 60 ASP M N 1 ATOM 8670 C CA . ASP F 3 80 ? 95.876 3.373 -2.117 1.00 95.23 ? 60 ASP M CA 1 ATOM 8671 C C . ASP F 3 80 ? 96.915 4.501 -2.111 1.00 94.21 ? 60 ASP M C 1 ATOM 8672 O O . ASP F 3 80 ? 97.306 4.996 -1.051 1.00 94.33 ? 60 ASP M O 1 ATOM 8673 C CB . ASP F 3 80 ? 96.464 2.068 -1.569 1.00 95.51 ? 60 ASP M CB 1 ATOM 8674 C CG . ASP F 3 80 ? 95.550 0.861 -1.830 1.00 96.45 ? 60 ASP M CG 1 ATOM 8675 O OD1 . ASP F 3 80 ? 95.142 0.650 -2.999 1.00 95.61 ? 60 ASP M OD1 1 ATOM 8676 O OD2 . ASP F 3 80 ? 95.239 0.118 -0.873 1.00 96.26 ? 60 ASP M OD2 1 ATOM 8677 N N . ARG F 3 81 ? 97.342 4.910 -3.304 1.00 92.23 ? 61 ARG M N 1 ATOM 8678 C CA . ARG F 3 81 ? 98.327 5.981 -3.457 1.00 90.65 ? 61 ARG M CA 1 ATOM 8679 C C . ARG F 3 81 ? 97.741 7.311 -3.005 1.00 89.68 ? 61 ARG M C 1 ATOM 8680 O O . ARG F 3 81 ? 98.455 8.205 -2.532 1.00 88.41 ? 61 ARG M O 1 ATOM 8681 C CB . ARG F 3 81 ? 98.733 6.125 -4.926 1.00 90.62 ? 61 ARG M CB 1 ATOM 8682 C CG . ARG F 3 81 ? 99.178 4.853 -5.597 1.00 90.48 ? 61 ARG M CG 1 ATOM 8683 C CD . ARG F 3 81 ? 99.646 5.139 -7.013 1.00 91.04 ? 61 ARG M CD 1 ATOM 8684 N NE . ARG F 3 81 ? 98.554 5.400 -7.951 1.00 90.88 ? 61 ARG M NE 1 ATOM 8685 C CZ . ARG F 3 81 ? 97.625 4.509 -8.289 1.00 91.62 ? 61 ARG M CZ 1 ATOM 8686 N NH1 . ARG F 3 81 ? 97.636 3.290 -7.763 1.00 91.17 ? 61 ARG M NH1 1 ATOM 8687 N NH2 . ARG F 3 81 ? 96.695 4.824 -9.180 1.00 91.70 ? 61 ARG M NH2 1 ATOM 8688 N N . PHE F 3 82 ? 96.426 7.421 -3.171 1.00 88.90 ? 62 PHE M N 1 ATOM 8689 C CA . PHE F 3 82 ? 95.680 8.628 -2.847 1.00 87.01 ? 62 PHE M CA 1 ATOM 8690 C C . PHE F 3 82 ? 95.378 8.812 -1.371 1.00 84.89 ? 62 PHE M C 1 ATOM 8691 O O . PHE F 3 82 ? 95.041 7.865 -0.667 1.00 84.82 ? 62 PHE M O 1 ATOM 8692 C CB . PHE F 3 82 ? 94.372 8.640 -3.640 1.00 88.09 ? 62 PHE M CB 1 ATOM 8693 C CG . PHE F 3 82 ? 94.567 8.604 -5.133 1.00 89.31 ? 62 PHE M CG 1 ATOM 8694 C CD1 . PHE F 3 82 ? 95.138 9.685 -5.802 1.00 90.01 ? 62 PHE M CD1 1 ATOM 8695 C CD2 . PHE F 3 82 ? 94.179 7.486 -5.872 1.00 89.88 ? 62 PHE M CD2 1 ATOM 8696 C CE1 . PHE F 3 82 ? 95.319 9.654 -7.187 1.00 90.43 ? 62 PHE M CE1 1 ATOM 8697 C CE2 . PHE F 3 82 ? 94.355 7.443 -7.259 1.00 90.28 ? 62 PHE M CE2 1 ATOM 8698 C CZ . PHE F 3 82 ? 94.925 8.529 -7.917 1.00 90.54 ? 62 PHE M CZ 1 ATOM 8699 N N . SER F 3 83 ? 95.499 10.053 -0.919 1.00 82.67 ? 63 SER M N 1 ATOM 8700 C CA . SER F 3 83 ? 95.235 10.398 0.465 1.00 81.37 ? 63 SER M CA 1 ATOM 8701 C C . SER F 3 83 ? 95.327 11.907 0.615 1.00 79.92 ? 63 SER M C 1 ATOM 8702 O O . SER F 3 83 ? 96.172 12.554 -0.010 1.00 78.45 ? 63 SER M O 1 ATOM 8703 C CB . SER F 3 83 ? 96.254 9.724 1.380 1.00 83.45 ? 63 SER M CB 1 ATOM 8704 O OG . SER F 3 83 ? 97.566 10.203 1.124 1.00 85.73 ? 63 SER M OG 1 ATOM 8705 N N . GLY F 3 84 ? 94.453 12.464 1.447 1.00 78.53 ? 64 GLY M N 1 ATOM 8706 C CA . GLY F 3 84 ? 94.454 13.902 1.655 1.00 76.62 ? 64 GLY M CA 1 ATOM 8707 C C . GLY F 3 84 ? 94.520 14.262 3.122 1.00 74.76 ? 64 GLY M C 1 ATOM 8708 O O . GLY F 3 84 ? 94.621 13.389 3.980 1.00 73.66 ? 64 GLY M O 1 ATOM 8709 N N . SER F 3 85 ? 94.454 15.552 3.415 1.00 74.08 ? 65 SER M N 1 ATOM 8710 C CA . SER F 3 85 ? 94.523 16.003 4.795 1.00 74.42 ? 65 SER M CA 1 ATOM 8711 C C . SER F 3 85 ? 94.205 17.485 4.921 1.00 73.96 ? 65 SER M C 1 ATOM 8712 O O . SER F 3 85 ? 94.599 18.295 4.082 1.00 73.71 ? 65 SER M O 1 ATOM 8713 C CB . SER F 3 85 ? 95.915 15.738 5.356 1.00 75.44 ? 65 SER M CB 1 ATOM 8714 O OG . SER F 3 85 ? 96.897 16.415 4.589 1.00 76.95 ? 65 SER M OG 1 ATOM 8715 N N . LYS F 3 86 ? 93.491 17.831 5.983 1.00 73.58 ? 66 LYS M N 1 ATOM 8716 C CA . LYS F 3 86 ? 93.107 19.213 6.233 1.00 73.35 ? 66 LYS M CA 1 ATOM 8717 C C . LYS F 3 86 ? 94.086 19.831 7.231 1.00 72.77 ? 66 LYS M C 1 ATOM 8718 O O . LYS F 3 86 ? 94.940 19.134 7.786 1.00 73.44 ? 66 LYS M O 1 ATOM 8719 C CB . LYS F 3 86 ? 91.673 19.258 6.783 1.00 72.91 ? 66 LYS M CB 1 ATOM 8720 C CG . LYS F 3 86 ? 91.113 20.645 7.002 1.00 72.17 ? 66 LYS M CG 1 ATOM 8721 C CD . LYS F 3 86 ? 89.681 20.570 7.484 1.00 73.51 ? 66 LYS M CD 1 ATOM 8722 C CE . LYS F 3 86 ? 89.206 21.917 8.001 1.00 74.40 ? 66 LYS M CE 1 ATOM 8723 N NZ . LYS F 3 86 ? 87.759 21.907 8.349 1.00 74.33 ? 66 LYS M NZ 1 ATOM 8724 N N . SER F 3 87 ? 93.958 21.132 7.456 1.00 70.80 ? 67 SER M N 1 ATOM 8725 C CA . SER F 3 87 ? 94.834 21.836 8.373 1.00 68.95 ? 67 SER M CA 1 ATOM 8726 C C . SER F 3 87 ? 94.441 23.306 8.405 1.00 67.57 ? 67 SER M C 1 ATOM 8727 O O . SER F 3 87 ? 94.281 23.939 7.361 1.00 65.55 ? 67 SER M O 1 ATOM 8728 C CB . SER F 3 87 ? 96.290 21.684 7.908 1.00 71.19 ? 67 SER M CB 1 ATOM 8729 O OG . SER F 3 87 ? 97.200 22.400 8.729 1.00 73.44 ? 67 SER M OG 1 ATOM 8730 N N . GLY F 3 88 ? 94.275 23.840 9.608 1.00 67.55 ? 68 GLY M N 1 ATOM 8731 C CA . GLY F 3 88 ? 93.914 25.238 9.753 1.00 69.58 ? 68 GLY M CA 1 ATOM 8732 C C . GLY F 3 88 ? 92.835 25.695 8.787 1.00 70.32 ? 68 GLY M C 1 ATOM 8733 O O . GLY F 3 88 ? 91.646 25.592 9.092 1.00 71.26 ? 68 GLY M O 1 ATOM 8734 N N . THR F 3 89 ? 93.246 26.209 7.629 1.00 69.41 ? 69 THR M N 1 ATOM 8735 C CA . THR F 3 89 ? 92.307 26.674 6.616 1.00 68.15 ? 69 THR M CA 1 ATOM 8736 C C . THR F 3 89 ? 92.880 26.401 5.246 1.00 67.63 ? 69 THR M C 1 ATOM 8737 O O . THR F 3 89 ? 92.745 27.210 4.328 1.00 67.10 ? 69 THR M O 1 ATOM 8738 C CB . THR F 3 89 ? 92.044 28.176 6.717 1.00 68.40 ? 69 THR M CB 1 ATOM 8739 O OG1 . THR F 3 89 ? 93.242 28.886 6.389 1.00 70.77 ? 69 THR M OG1 1 ATOM 8740 C CG2 . THR F 3 89 ? 91.593 28.548 8.117 1.00 68.75 ? 69 THR M CG2 1 ATOM 8741 N N . SER F 3 90 ? 93.527 25.250 5.124 1.00 67.40 ? 70 SER M N 1 ATOM 8742 C CA . SER F 3 90 ? 94.137 24.827 3.874 1.00 67.87 ? 70 SER M CA 1 ATOM 8743 C C . SER F 3 90 ? 94.365 23.332 4.010 1.00 67.88 ? 70 SER M C 1 ATOM 8744 O O . SER F 3 90 ? 94.793 22.865 5.057 1.00 69.95 ? 70 SER M O 1 ATOM 8745 C CB . SER F 3 90 ? 95.493 25.528 3.665 1.00 68.73 ? 70 SER M CB 1 ATOM 8746 O OG . SER F 3 90 ? 95.395 26.948 3.706 1.00 68.74 ? 70 SER M OG 1 ATOM 8747 N N . ALA F 3 91 ? 94.073 22.571 2.970 1.00 67.10 ? 71 ALA M N 1 ATOM 8748 C CA . ALA F 3 91 ? 94.296 21.139 3.035 1.00 67.45 ? 71 ALA M CA 1 ATOM 8749 C C . ALA F 3 91 ? 94.965 20.765 1.735 1.00 68.57 ? 71 ALA M C 1 ATOM 8750 O O . ALA F 3 91 ? 95.269 21.633 0.930 1.00 68.78 ? 71 ALA M O 1 ATOM 8751 C CB . ALA F 3 91 ? 92.991 20.416 3.178 1.00 68.27 ? 71 ALA M CB 1 ATOM 8752 N N . SER F 3 92 ? 95.196 19.485 1.506 1.00 70.22 ? 72 SER M N 1 ATOM 8753 C CA . SER F 3 92 ? 95.839 19.122 0.264 1.00 72.63 ? 72 SER M CA 1 ATOM 8754 C C . SER F 3 92 ? 95.831 17.644 -0.079 1.00 74.27 ? 72 SER M C 1 ATOM 8755 O O . SER F 3 92 ? 95.914 16.777 0.790 1.00 73.48 ? 72 SER M O 1 ATOM 8756 C CB . SER F 3 92 ? 97.265 19.652 0.276 1.00 73.60 ? 72 SER M CB 1 ATOM 8757 O OG . SER F 3 92 ? 97.795 19.561 1.583 1.00 75.99 ? 72 SER M OG 1 ATOM 8758 N N . LEU F 3 93 ? 95.705 17.382 -1.375 1.00 76.73 ? 73 LEU M N 1 ATOM 8759 C CA . LEU F 3 93 ? 95.697 16.032 -1.913 1.00 78.29 ? 73 LEU M CA 1 ATOM 8760 C C . LEU F 3 93 ? 97.137 15.731 -2.314 1.00 79.46 ? 73 LEU M C 1 ATOM 8761 O O . LEU F 3 93 ? 97.888 16.629 -2.699 1.00 78.51 ? 73 LEU M O 1 ATOM 8762 C CB . LEU F 3 93 ? 94.775 15.951 -3.137 1.00 77.02 ? 73 LEU M CB 1 ATOM 8763 C CG . LEU F 3 93 ? 94.838 14.691 -4.011 1.00 76.99 ? 73 LEU M CG 1 ATOM 8764 C CD1 . LEU F 3 93 ? 94.413 13.466 -3.224 1.00 76.29 ? 73 LEU M CD1 1 ATOM 8765 C CD2 . LEU F 3 93 ? 93.937 14.874 -5.212 1.00 76.96 ? 73 LEU M CD2 1 ATOM 8766 N N . ALA F 3 94 ? 97.519 14.468 -2.212 1.00 80.74 ? 74 ALA M N 1 ATOM 8767 C CA . ALA F 3 94 ? 98.865 14.073 -2.557 1.00 82.74 ? 74 ALA M CA 1 ATOM 8768 C C . ALA F 3 94 ? 98.867 12.673 -3.146 1.00 84.29 ? 74 ALA M C 1 ATOM 8769 O O . ALA F 3 94 ? 98.315 11.732 -2.567 1.00 83.87 ? 74 ALA M O 1 ATOM 8770 C CB . ALA F 3 94 ? 99.758 14.138 -1.319 1.00 82.16 ? 74 ALA M CB 1 ATOM 8771 N N . ILE F 3 95 ? 99.484 12.546 -4.313 1.00 86.54 ? 75 ILE M N 1 ATOM 8772 C CA . ILE F 3 95 ? 99.564 11.258 -4.977 1.00 89.09 ? 75 ILE M CA 1 ATOM 8773 C C . ILE F 3 95 ? 100.979 10.722 -4.806 1.00 89.99 ? 75 ILE M C 1 ATOM 8774 O O . ILE F 3 95 ? 101.938 11.305 -5.319 1.00 90.00 ? 75 ILE M O 1 ATOM 8775 C CB . ILE F 3 95 ? 99.254 11.376 -6.490 1.00 89.65 ? 75 ILE M CB 1 ATOM 8776 C CG1 . ILE F 3 95 ? 98.043 12.288 -6.705 1.00 89.26 ? 75 ILE M CG1 1 ATOM 8777 C CG2 . ILE F 3 95 ? 98.970 9.986 -7.074 1.00 89.60 ? 75 ILE M CG2 1 ATOM 8778 C CD1 . ILE F 3 95 ? 97.716 12.548 -8.157 1.00 88.39 ? 75 ILE M CD1 1 ATOM 8779 N N . SER F 3 96 ? 101.098 9.625 -4.060 1.00 90.95 ? 76 SER M N 1 ATOM 8780 C CA . SER F 3 96 ? 102.388 8.985 -3.824 1.00 90.90 ? 76 SER M CA 1 ATOM 8781 C C . SER F 3 96 ? 102.553 7.908 -4.881 1.00 91.12 ? 76 SER M C 1 ATOM 8782 O O . SER F 3 96 ? 101.654 7.090 -5.085 1.00 90.57 ? 76 SER M O 1 ATOM 8783 C CB . SER F 3 96 ? 102.444 8.359 -2.422 1.00 90.29 ? 76 SER M CB 1 ATOM 8784 O OG . SER F 3 96 ? 102.568 9.349 -1.412 1.00 89.50 ? 76 SER M OG 1 ATOM 8785 N N . GLY F 3 97 ? 103.701 7.918 -5.551 1.00 91.55 ? 77 GLY M N 1 ATOM 8786 C CA . GLY F 3 97 ? 103.951 6.942 -6.593 1.00 92.45 ? 77 GLY M CA 1 ATOM 8787 C C . GLY F 3 97 ? 103.262 7.413 -7.854 1.00 93.18 ? 77 GLY M C 1 ATOM 8788 O O . GLY F 3 97 ? 102.766 6.606 -8.649 1.00 92.76 ? 77 GLY M O 1 ATOM 8789 N N . LEU F 3 98 ? 103.226 8.737 -8.008 1.00 94.12 ? 78 LEU M N 1 ATOM 8790 C CA . LEU F 3 98 ? 102.609 9.409 -9.149 1.00 95.04 ? 78 LEU M CA 1 ATOM 8791 C C . LEU F 3 98 ? 102.703 8.540 -10.393 1.00 95.50 ? 78 LEU M C 1 ATOM 8792 O O . LEU F 3 98 ? 103.731 7.926 -10.642 1.00 96.67 ? 78 LEU M O 1 ATOM 8793 C CB . LEU F 3 98 ? 103.303 10.756 -9.379 1.00 94.57 ? 78 LEU M CB 1 ATOM 8794 C CG . LEU F 3 98 ? 102.858 11.666 -10.523 1.00 95.40 ? 78 LEU M CG 1 ATOM 8795 C CD1 . LEU F 3 98 ? 103.326 11.098 -11.858 1.00 95.02 ? 78 LEU M CD1 1 ATOM 8796 C CD2 . LEU F 3 98 ? 101.345 11.829 -10.481 1.00 95.51 ? 78 LEU M CD2 1 ATOM 8797 N N . ARG F 3 99 ? 101.633 8.481 -11.173 1.00 95.73 ? 79 ARG M N 1 ATOM 8798 C CA . ARG F 3 99 ? 101.645 7.655 -12.370 1.00 96.55 ? 79 ARG M CA 1 ATOM 8799 C C . ARG F 3 99 ? 101.134 8.329 -13.641 1.00 97.90 ? 79 ARG M C 1 ATOM 8800 O O . ARG F 3 99 ? 100.961 9.548 -13.698 1.00 98.77 ? 79 ARG M O 1 ATOM 8801 C CB . ARG F 3 99 ? 100.838 6.383 -12.136 1.00 96.07 ? 79 ARG M CB 1 ATOM 8802 C CG . ARG F 3 99 ? 101.456 5.379 -11.196 1.00 95.44 ? 79 ARG M CG 1 ATOM 8803 C CD . ARG F 3 99 ? 101.205 3.963 -11.705 1.00 96.06 ? 79 ARG M CD 1 ATOM 8804 N NE . ARG F 3 99 ? 99.835 3.749 -12.183 1.00 96.38 ? 79 ARG M NE 1 ATOM 8805 C CZ . ARG F 3 99 ? 99.370 4.127 -13.376 1.00 96.96 ? 79 ARG M CZ 1 ATOM 8806 N NH1 . ARG F 3 99 ? 100.156 4.749 -14.246 1.00 95.78 ? 79 ARG M NH1 1 ATOM 8807 N NH2 . ARG F 3 99 ? 98.106 3.881 -13.704 1.00 97.13 ? 79 ARG M NH2 1 ATOM 8808 N N . SER F 3 100 ? 100.892 7.508 -14.660 1.00 98.55 ? 80 SER M N 1 ATOM 8809 C CA . SER F 3 100 ? 100.412 7.972 -15.955 1.00 98.72 ? 80 SER M CA 1 ATOM 8810 C C . SER F 3 100 ? 98.904 8.174 -15.941 1.00 98.55 ? 80 SER M C 1 ATOM 8811 O O . SER F 3 100 ? 98.413 9.269 -16.213 1.00 98.44 ? 80 SER M O 1 ATOM 8812 C CB . SER F 3 100 ? 100.788 6.957 -17.039 1.00 99.56 ? 80 SER M CB 1 ATOM 8813 O OG . SER F 3 100 ? 100.311 5.659 -16.713 1.00 99.49 ? 80 SER M OG 1 ATOM 8814 N N . GLU F 3 101 ? 98.171 7.113 -15.627 1.00 97.74 ? 81 GLU M N 1 ATOM 8815 C CA . GLU F 3 101 ? 96.721 7.190 -15.580 1.00 96.95 ? 81 GLU M CA 1 ATOM 8816 C C . GLU F 3 101 ? 96.293 7.892 -14.297 1.00 95.65 ? 81 GLU M C 1 ATOM 8817 O O . GLU F 3 101 ? 95.247 7.602 -13.721 1.00 95.81 ? 81 GLU M O 1 ATOM 8818 C CB . GLU F 3 101 ? 96.127 5.785 -15.676 1.00 98.08 ? 81 GLU M CB 1 ATOM 8819 C CG . GLU F 3 101 ? 96.511 5.079 -16.978 1.00 99.67 ? 81 GLU M CG 1 ATOM 8820 C CD . GLU F 3 101 ? 96.007 3.648 -17.059 1.00 100.14 ? 81 GLU M CD 1 ATOM 8821 O OE1 . GLU F 3 101 ? 96.260 2.880 -16.105 1.00 100.31 ? 81 GLU M OE1 1 ATOM 8822 O OE2 . GLU F 3 101 ? 95.370 3.290 -18.078 1.00 99.68 ? 81 GLU M OE2 1 ATOM 8823 N N . ASP F 3 102 ? 97.138 8.821 -13.864 1.00 94.06 ? 82 ASP M N 1 ATOM 8824 C CA . ASP F 3 102 ? 96.911 9.628 -12.672 1.00 92.73 ? 82 ASP M CA 1 ATOM 8825 C C . ASP F 3 102 ? 96.955 11.090 -13.098 1.00 91.24 ? 82 ASP M C 1 ATOM 8826 O O . ASP F 3 102 ? 96.893 11.999 -12.268 1.00 90.85 ? 82 ASP M O 1 ATOM 8827 C CB . ASP F 3 102 ? 98.002 9.366 -11.631 1.00 93.97 ? 82 ASP M CB 1 ATOM 8828 C CG . ASP F 3 102 ? 97.795 8.067 -10.884 1.00 95.33 ? 82 ASP M CG 1 ATOM 8829 O OD1 . ASP F 3 102 ? 97.254 7.117 -11.493 1.00 95.96 ? 82 ASP M OD1 1 ATOM 8830 O OD2 . ASP F 3 102 ? 98.184 7.997 -9.693 1.00 95.64 ? 82 ASP M OD2 1 ATOM 8831 N N . GLU F 3 103 ? 97.085 11.310 -14.403 1.00 89.33 ? 83 GLU M N 1 ATOM 8832 C CA . GLU F 3 103 ? 97.118 12.665 -14.930 1.00 87.60 ? 83 GLU M CA 1 ATOM 8833 C C . GLU F 3 103 ? 95.689 13.062 -15.287 1.00 85.17 ? 83 GLU M C 1 ATOM 8834 O O . GLU F 3 103 ? 94.978 12.351 -16.009 1.00 85.31 ? 83 GLU M O 1 ATOM 8835 C CB . GLU F 3 103 ? 98.040 12.760 -16.159 1.00 89.45 ? 83 GLU M CB 1 ATOM 8836 C CG . GLU F 3 103 ? 97.494 12.156 -17.451 1.00 91.84 ? 83 GLU M CG 1 ATOM 8837 C CD . GLU F 3 103 ? 98.579 11.922 -18.497 1.00 93.10 ? 83 GLU M CD 1 ATOM 8838 O OE1 . GLU F 3 103 ? 99.411 12.835 -18.723 1.00 93.47 ? 83 GLU M OE1 1 ATOM 8839 O OE2 . GLU F 3 103 ? 98.592 10.820 -19.094 1.00 92.66 ? 83 GLU M OE2 1 ATOM 8840 N N . ALA F 3 104 ? 95.268 14.198 -14.752 1.00 80.60 ? 84 ALA M N 1 ATOM 8841 C CA . ALA F 3 104 ? 93.932 14.697 -14.992 1.00 75.33 ? 84 ALA M CA 1 ATOM 8842 C C . ALA F 3 104 ? 93.801 15.969 -14.186 1.00 71.92 ? 84 ALA M C 1 ATOM 8843 O O . ALA F 3 104 ? 94.777 16.444 -13.607 1.00 69.81 ? 84 ALA M O 1 ATOM 8844 C CB . ALA F 3 104 ? 92.914 13.671 -14.533 1.00 75.52 ? 84 ALA M CB 1 ATOM 8845 N N . ASP F 3 105 ? 92.605 16.536 -14.156 1.00 68.73 ? 85 ASP M N 1 ATOM 8846 C CA . ASP F 3 105 ? 92.418 17.736 -13.372 1.00 66.96 ? 85 ASP M CA 1 ATOM 8847 C C . ASP F 3 105 ? 91.972 17.307 -11.982 1.00 64.25 ? 85 ASP M C 1 ATOM 8848 O O . ASP F 3 105 ? 91.244 16.327 -11.827 1.00 63.72 ? 85 ASP M O 1 ATOM 8849 C CB . ASP F 3 105 ? 91.384 18.663 -14.019 1.00 69.27 ? 85 ASP M CB 1 ATOM 8850 C CG . ASP F 3 105 ? 91.954 19.445 -15.201 1.00 70.21 ? 85 ASP M CG 1 ATOM 8851 O OD1 . ASP F 3 105 ? 91.613 20.643 -15.354 1.00 70.05 ? 85 ASP M OD1 1 ATOM 8852 O OD2 . ASP F 3 105 ? 92.737 18.857 -15.978 1.00 70.01 ? 85 ASP M OD2 1 ATOM 8853 N N . TYR F 3 106 ? 92.436 18.027 -10.971 1.00 60.48 ? 86 TYR M N 1 ATOM 8854 C CA . TYR F 3 106 ? 92.085 17.706 -9.606 1.00 57.72 ? 86 TYR M CA 1 ATOM 8855 C C . TYR F 3 106 ? 91.455 18.902 -8.939 1.00 57.67 ? 86 TYR M C 1 ATOM 8856 O O . TYR F 3 106 ? 92.126 19.911 -8.690 1.00 57.93 ? 86 TYR M O 1 ATOM 8857 C CB . TYR F 3 106 ? 93.328 17.264 -8.829 1.00 56.44 ? 86 TYR M CB 1 ATOM 8858 C CG . TYR F 3 106 ? 93.836 15.908 -9.267 1.00 55.60 ? 86 TYR M CG 1 ATOM 8859 C CD1 . TYR F 3 106 ? 94.437 15.733 -10.516 1.00 54.44 ? 86 TYR M CD1 1 ATOM 8860 C CD2 . TYR F 3 106 ? 93.624 14.779 -8.479 1.00 55.27 ? 86 TYR M CD2 1 ATOM 8861 C CE1 . TYR F 3 106 ? 94.802 14.467 -10.969 1.00 52.70 ? 86 TYR M CE1 1 ATOM 8862 C CE2 . TYR F 3 106 ? 93.982 13.509 -8.926 1.00 54.03 ? 86 TYR M CE2 1 ATOM 8863 C CZ . TYR F 3 106 ? 94.565 13.364 -10.170 1.00 52.84 ? 86 TYR M CZ 1 ATOM 8864 O OH . TYR F 3 106 ? 94.882 12.110 -10.619 1.00 52.35 ? 86 TYR M OH 1 ATOM 8865 N N . TYR F 3 107 ? 90.156 18.796 -8.667 1.00 56.08 ? 87 TYR M N 1 ATOM 8866 C CA . TYR F 3 107 ? 89.426 19.878 -8.006 1.00 53.99 ? 87 TYR M CA 1 ATOM 8867 C C . TYR F 3 107 ? 89.206 19.492 -6.540 1.00 54.42 ? 87 TYR M C 1 ATOM 8868 O O . TYR F 3 107 ? 89.010 18.312 -6.221 1.00 53.71 ? 87 TYR M O 1 ATOM 8869 C CB . TYR F 3 107 ? 88.060 20.114 -8.677 1.00 50.22 ? 87 TYR M CB 1 ATOM 8870 C CG . TYR F 3 107 ? 88.089 20.398 -10.166 1.00 45.90 ? 87 TYR M CG 1 ATOM 8871 C CD1 . TYR F 3 107 ? 88.103 21.709 -10.653 1.00 44.73 ? 87 TYR M CD1 1 ATOM 8872 C CD2 . TYR F 3 107 ? 88.101 19.352 -11.088 1.00 43.71 ? 87 TYR M CD2 1 ATOM 8873 C CE1 . TYR F 3 107 ? 88.130 21.971 -12.030 1.00 44.03 ? 87 TYR M CE1 1 ATOM 8874 C CE2 . TYR F 3 107 ? 88.129 19.595 -12.461 1.00 43.99 ? 87 TYR M CE2 1 ATOM 8875 C CZ . TYR F 3 107 ? 88.145 20.905 -12.930 1.00 46.79 ? 87 TYR M CZ 1 ATOM 8876 O OH . TYR F 3 107 ? 88.198 21.131 -14.299 1.00 48.61 ? 87 TYR M OH 1 ATOM 8877 N N . CYS F 3 108 ? 89.269 20.487 -5.660 1.00 54.19 ? 88 CYS M N 1 ATOM 8878 C CA . CYS F 3 108 ? 89.041 20.294 -4.236 1.00 56.72 ? 88 CYS M CA 1 ATOM 8879 C C . CYS F 3 108 ? 87.860 21.186 -3.933 1.00 54.99 ? 88 CYS M C 1 ATOM 8880 O O . CYS F 3 108 ? 87.748 22.271 -4.497 1.00 53.91 ? 88 CYS M O 1 ATOM 8881 C CB . CYS F 3 108 ? 90.248 20.743 -3.416 1.00 62.20 ? 88 CYS M CB 1 ATOM 8882 S SG . CYS F 3 108 ? 90.837 22.431 -3.786 1.00 74.12 ? 88 CYS M SG 1 ATOM 8883 N N . ALA F 3 109 ? 86.975 20.741 -3.050 1.00 54.20 ? 89 ALA M N 1 ATOM 8884 C CA . ALA F 3 109 ? 85.800 21.539 -2.739 1.00 52.87 ? 89 ALA M CA 1 ATOM 8885 C C . ALA F 3 109 ? 85.305 21.373 -1.320 1.00 51.03 ? 89 ALA M C 1 ATOM 8886 O O . ALA F 3 109 ? 85.565 20.363 -0.674 1.00 50.37 ? 89 ALA M O 1 ATOM 8887 C CB . ALA F 3 109 ? 84.683 21.203 -3.715 1.00 53.54 ? 89 ALA M CB 1 ATOM 8888 N N . THR F 3 110 ? 84.585 22.385 -0.850 1.00 49.67 ? 90 THR M N 1 ATOM 8889 C CA . THR F 3 110 ? 84.024 22.385 0.492 1.00 50.22 ? 90 THR M CA 1 ATOM 8890 C C . THR F 3 110 ? 82.813 23.295 0.545 1.00 49.81 ? 90 THR M C 1 ATOM 8891 O O . THR F 3 110 ? 82.560 24.066 -0.378 1.00 50.12 ? 90 THR M O 1 ATOM 8892 C CB . THR F 3 110 ? 85.020 22.912 1.551 1.00 51.34 ? 90 THR M CB 1 ATOM 8893 O OG1 . THR F 3 110 ? 85.087 24.344 1.489 1.00 47.86 ? 90 THR M OG1 1 ATOM 8894 C CG2 . THR F 3 110 ? 86.402 22.326 1.319 1.00 51.39 ? 90 THR M CG2 1 ATOM 8895 N N . TRP F 3 111 ? 82.075 23.212 1.641 1.00 48.48 ? 91 TRP M N 1 ATOM 8896 C CA . TRP F 3 111 ? 80.901 24.041 1.808 1.00 49.41 ? 91 TRP M CA 1 ATOM 8897 C C . TRP F 3 111 ? 81.347 25.366 2.414 1.00 51.93 ? 91 TRP M C 1 ATOM 8898 O O . TRP F 3 111 ? 82.214 25.376 3.284 1.00 53.71 ? 91 TRP M O 1 ATOM 8899 C CB . TRP F 3 111 ? 79.901 23.327 2.717 1.00 45.54 ? 91 TRP M CB 1 ATOM 8900 C CG . TRP F 3 111 ? 78.712 24.150 3.062 1.00 43.06 ? 91 TRP M CG 1 ATOM 8901 C CD1 . TRP F 3 111 ? 78.594 25.019 4.103 1.00 43.16 ? 91 TRP M CD1 1 ATOM 8902 C CD2 . TRP F 3 111 ? 77.481 24.214 2.344 1.00 42.55 ? 91 TRP M CD2 1 ATOM 8903 N NE1 . TRP F 3 111 ? 77.363 25.625 4.081 1.00 43.16 ? 91 TRP M NE1 1 ATOM 8904 C CE2 . TRP F 3 111 ? 76.659 25.151 3.009 1.00 42.28 ? 91 TRP M CE2 1 ATOM 8905 C CE3 . TRP F 3 111 ? 76.990 23.572 1.202 1.00 43.06 ? 91 TRP M CE3 1 ATOM 8906 C CZ2 . TRP F 3 111 ? 75.376 25.464 2.571 1.00 41.12 ? 91 TRP M CZ2 1 ATOM 8907 C CZ3 . TRP F 3 111 ? 75.710 23.882 0.767 1.00 43.05 ? 91 TRP M CZ3 1 ATOM 8908 C CH2 . TRP F 3 111 ? 74.919 24.823 1.452 1.00 42.53 ? 91 TRP M CH2 1 ATOM 8909 N N . ASP F 3 112 ? 80.778 26.481 1.965 1.00 52.71 ? 92 ASP M N 1 ATOM 8910 C CA . ASP F 3 112 ? 81.173 27.773 2.518 1.00 55.54 ? 92 ASP M CA 1 ATOM 8911 C C . ASP F 3 112 ? 80.058 28.407 3.340 1.00 55.32 ? 92 ASP M C 1 ATOM 8912 O O . ASP F 3 112 ? 79.069 28.884 2.790 1.00 54.54 ? 92 ASP M O 1 ATOM 8913 C CB . ASP F 3 112 ? 81.578 28.719 1.397 1.00 60.97 ? 92 ASP M CB 1 ATOM 8914 C CG . ASP F 3 112 ? 82.176 30.011 1.915 1.00 64.51 ? 92 ASP M CG 1 ATOM 8915 O OD1 . ASP F 3 112 ? 83.292 29.961 2.489 1.00 66.10 ? 92 ASP M OD1 1 ATOM 8916 O OD2 . ASP F 3 112 ? 81.524 31.068 1.745 1.00 65.22 ? 92 ASP M OD2 1 ATOM 8917 N N . ASP F 3 113 ? 80.246 28.429 4.657 1.00 56.11 ? 93 ASP M N 1 ATOM 8918 C CA . ASP F 3 113 ? 79.258 28.953 5.597 1.00 57.89 ? 93 ASP M CA 1 ATOM 8919 C C . ASP F 3 113 ? 78.869 30.415 5.443 1.00 58.52 ? 93 ASP M C 1 ATOM 8920 O O . ASP F 3 113 ? 77.922 30.878 6.082 1.00 57.36 ? 93 ASP M O 1 ATOM 8921 C CB . ASP F 3 113 ? 79.729 28.708 7.029 1.00 60.61 ? 93 ASP M CB 1 ATOM 8922 C CG . ASP F 3 113 ? 79.853 27.226 7.357 1.00 65.81 ? 93 ASP M CG 1 ATOM 8923 O OD1 . ASP F 3 113 ? 78.835 26.509 7.257 1.00 68.30 ? 93 ASP M OD1 1 ATOM 8924 O OD2 . ASP F 3 113 ? 80.964 26.769 7.714 1.00 68.34 ? 93 ASP M OD2 1 ATOM 8925 N N . SER F 3 114 ? 79.585 31.146 4.594 1.00 58.83 ? 94 SER M N 1 ATOM 8926 C CA . SER F 3 114 ? 79.285 32.559 4.386 1.00 57.01 ? 94 SER M CA 1 ATOM 8927 C C . SER F 3 114 ? 78.494 32.765 3.112 1.00 56.33 ? 94 SER M C 1 ATOM 8928 O O . SER F 3 114 ? 77.724 33.710 3.005 1.00 57.06 ? 94 SER M O 1 ATOM 8929 C CB . SER F 3 114 ? 80.572 33.355 4.324 1.00 57.12 ? 94 SER M CB 1 ATOM 8930 O OG . SER F 3 114 ? 81.501 32.683 3.500 1.00 60.16 ? 94 SER M OG 1 ATOM 8931 N N . LEU F 3 115 ? 78.694 31.876 2.144 1.00 55.35 ? 95 LEU M N 1 ATOM 8932 C CA . LEU F 3 115 ? 77.980 31.939 0.872 1.00 53.95 ? 95 LEU M CA 1 ATOM 8933 C C . LEU F 3 115 ? 76.743 31.067 0.959 1.00 54.26 ? 95 LEU M C 1 ATOM 8934 O O . LEU F 3 115 ? 75.718 31.346 0.327 1.00 53.71 ? 95 LEU M O 1 ATOM 8935 C CB . LEU F 3 115 ? 78.869 31.425 -0.251 1.00 53.17 ? 95 LEU M CB 1 ATOM 8936 C CG . LEU F 3 115 ? 79.830 32.465 -0.795 1.00 52.56 ? 95 LEU M CG 1 ATOM 8937 C CD1 . LEU F 3 115 ? 80.963 31.810 -1.559 1.00 52.12 ? 95 LEU M CD1 1 ATOM 8938 C CD2 . LEU F 3 115 ? 79.026 33.410 -1.669 1.00 52.77 ? 95 LEU M CD2 1 ATOM 8939 N N . SER F 3 116 A 76.863 30.003 1.754 1.00 53.07 ? 95 SER M N 1 ATOM 8940 C CA . SER F 3 116 A 75.784 29.046 1.953 1.00 50.09 ? 95 SER M CA 1 ATOM 8941 C C . SER F 3 116 A 75.687 28.220 0.689 1.00 48.64 ? 95 SER M C 1 ATOM 8942 O O . SER F 3 116 A 74.598 28.014 0.157 1.00 47.51 ? 95 SER M O 1 ATOM 8943 C CB . SER F 3 116 A 74.464 29.772 2.199 1.00 49.43 ? 95 SER M CB 1 ATOM 8944 O OG . SER F 3 116 A 73.780 29.202 3.296 1.00 49.65 ? 95 SER M OG 1 ATOM 8945 N N . ALA F 3 117 B 76.843 27.764 0.211 1.00 46.77 ? 95 ALA M N 1 ATOM 8946 C CA . ALA F 3 117 B 76.908 26.973 -1.006 1.00 46.04 ? 95 ALA M CA 1 ATOM 8947 C C . ALA F 3 117 B 78.223 26.241 -1.112 1.00 45.89 ? 95 ALA M C 1 ATOM 8948 O O . ALA F 3 117 B 79.214 26.635 -0.499 1.00 46.97 ? 95 ALA M O 1 ATOM 8949 C CB . ALA F 3 117 B 76.738 27.867 -2.211 1.00 45.78 ? 95 ALA M CB 1 ATOM 8950 N N . VAL F 3 118 ? 78.222 25.165 -1.886 1.00 44.84 ? 96 VAL M N 1 ATOM 8951 C CA . VAL F 3 118 ? 79.427 24.393 -2.101 1.00 46.52 ? 96 VAL M CA 1 ATOM 8952 C C . VAL F 3 118 ? 80.357 25.296 -2.894 1.00 48.72 ? 96 VAL M C 1 ATOM 8953 O O . VAL F 3 118 ? 79.894 26.122 -3.682 1.00 50.10 ? 96 VAL M O 1 ATOM 8954 C CB . VAL F 3 118 ? 79.139 23.123 -2.916 1.00 45.94 ? 96 VAL M CB 1 ATOM 8955 C CG1 . VAL F 3 118 ? 80.432 22.417 -3.265 1.00 42.85 ? 96 VAL M CG1 1 ATOM 8956 C CG2 . VAL F 3 118 ? 78.245 22.209 -2.121 1.00 47.06 ? 96 VAL M CG2 1 ATOM 8957 N N . ILE F 3 119 ? 81.662 25.152 -2.676 1.00 49.59 ? 97 ILE M N 1 ATOM 8958 C CA . ILE F 3 119 ? 82.649 25.965 -3.375 1.00 49.47 ? 97 ILE M CA 1 ATOM 8959 C C . ILE F 3 119 ? 83.682 25.048 -3.975 1.00 49.13 ? 97 ILE M C 1 ATOM 8960 O O . ILE F 3 119 ? 84.201 24.172 -3.295 1.00 48.76 ? 97 ILE M O 1 ATOM 8961 C CB . ILE F 3 119 ? 83.386 26.940 -2.415 1.00 50.97 ? 97 ILE M CB 1 ATOM 8962 C CG1 . ILE F 3 119 ? 82.382 27.829 -1.686 1.00 52.29 ? 97 ILE M CG1 1 ATOM 8963 C CG2 . ILE F 3 119 ? 84.310 27.847 -3.195 1.00 53.13 ? 97 ILE M CG2 1 ATOM 8964 C CD1 . ILE F 3 119 ? 81.535 28.683 -2.609 1.00 53.63 ? 97 ILE M CD1 1 ATOM 8965 N N . PHE F 3 120 ? 83.974 25.242 -5.253 1.00 50.29 ? 98 PHE M N 1 ATOM 8966 C CA . PHE F 3 120 ? 84.985 24.433 -5.925 1.00 51.26 ? 98 PHE M CA 1 ATOM 8967 C C . PHE F 3 120 ? 86.262 25.255 -6.105 1.00 53.70 ? 98 PHE M C 1 ATOM 8968 O O . PHE F 3 120 ? 86.212 26.477 -6.305 1.00 52.57 ? 98 PHE M O 1 ATOM 8969 C CB . PHE F 3 120 ? 84.502 23.988 -7.301 1.00 48.94 ? 98 PHE M CB 1 ATOM 8970 C CG . PHE F 3 120 ? 83.660 22.765 -7.282 1.00 47.85 ? 98 PHE M CG 1 ATOM 8971 C CD1 . PHE F 3 120 ? 82.306 22.840 -6.975 1.00 46.23 ? 98 PHE M CD1 1 ATOM 8972 C CD2 . PHE F 3 120 ? 84.225 21.523 -7.567 1.00 48.36 ? 98 PHE M CD2 1 ATOM 8973 C CE1 . PHE F 3 120 ? 81.525 21.700 -6.951 1.00 45.10 ? 98 PHE M CE1 1 ATOM 8974 C CE2 . PHE F 3 120 ? 83.453 20.366 -7.546 1.00 47.49 ? 98 PHE M CE2 1 ATOM 8975 C CZ . PHE F 3 120 ? 82.097 20.453 -7.236 1.00 47.78 ? 98 PHE M CZ 1 ATOM 8976 N N . GLY F 3 121 ? 87.406 24.585 -6.021 1.00 55.39 ? 99 GLY M N 1 ATOM 8977 C CA . GLY F 3 121 ? 88.661 25.279 -6.214 1.00 58.96 ? 99 GLY M CA 1 ATOM 8978 C C . GLY F 3 121 ? 88.824 25.605 -7.688 1.00 61.98 ? 99 GLY M C 1 ATOM 8979 O O . GLY F 3 121 ? 87.939 25.324 -8.503 1.00 62.69 ? 99 GLY M O 1 ATOM 8980 N N . GLY F 3 122 ? 89.946 26.228 -8.027 1.00 63.70 ? 100 GLY M N 1 ATOM 8981 C CA . GLY F 3 122 ? 90.201 26.585 -9.407 1.00 65.53 ? 100 GLY M CA 1 ATOM 8982 C C . GLY F 3 122 ? 90.428 25.332 -10.215 1.00 65.97 ? 100 GLY M C 1 ATOM 8983 O O . GLY F 3 122 ? 90.034 25.245 -11.372 1.00 66.49 ? 100 GLY M O 1 ATOM 8984 N N . GLY F 3 123 ? 91.058 24.354 -9.580 1.00 66.65 ? 101 GLY M N 1 ATOM 8985 C CA . GLY F 3 123 ? 91.358 23.102 -10.240 1.00 68.50 ? 101 GLY M CA 1 ATOM 8986 C C . GLY F 3 123 ? 92.847 23.082 -10.498 1.00 70.18 ? 101 GLY M C 1 ATOM 8987 O O . GLY F 3 123 ? 93.460 24.140 -10.681 1.00 70.07 ? 101 GLY M O 1 ATOM 8988 N N . THR F 3 124 ? 93.437 21.893 -10.495 1.00 71.24 ? 102 THR M N 1 ATOM 8989 C CA . THR F 3 124 ? 94.862 21.762 -10.750 1.00 72.39 ? 102 THR M CA 1 ATOM 8990 C C . THR F 3 124 ? 95.106 20.681 -11.780 1.00 74.62 ? 102 THR M C 1 ATOM 8991 O O . THR F 3 124 ? 94.805 19.506 -11.551 1.00 73.43 ? 102 THR M O 1 ATOM 8992 C CB . THR F 3 124 ? 95.649 21.431 -9.464 1.00 71.48 ? 102 THR M CB 1 ATOM 8993 O OG1 . THR F 3 124 ? 95.753 22.608 -8.651 1.00 69.88 ? 102 THR M OG1 1 ATOM 8994 C CG2 . THR F 3 124 ? 97.037 20.932 -9.803 1.00 70.52 ? 102 THR M CG2 1 ATOM 8995 N N . LYS F 3 125 ? 95.646 21.096 -12.923 1.00 77.69 ? 103 LYS M N 1 ATOM 8996 C CA . LYS F 3 125 ? 95.945 20.170 -14.005 1.00 80.87 ? 103 LYS M CA 1 ATOM 8997 C C . LYS F 3 125 ? 97.284 19.488 -13.749 1.00 83.29 ? 103 LYS M C 1 ATOM 8998 O O . LYS F 3 125 ? 98.230 20.111 -13.257 1.00 82.95 ? 103 LYS M O 1 ATOM 8999 C CB . LYS F 3 125 ? 95.975 20.907 -15.348 1.00 79.45 ? 103 LYS M CB 1 ATOM 9000 C CG . LYS F 3 125 ? 96.015 19.968 -16.544 1.00 79.89 ? 103 LYS M CG 1 ATOM 9001 C CD . LYS F 3 125 ? 95.898 20.700 -17.880 1.00 81.40 ? 103 LYS M CD 1 ATOM 9002 C CE . LYS F 3 125 ? 94.594 21.499 -18.021 1.00 81.69 ? 103 LYS M CE 1 ATOM 9003 N NZ . LYS F 3 125 ? 94.597 22.778 -17.246 1.00 79.93 ? 103 LYS M NZ 1 ATOM 9004 N N . LEU F 3 126 ? 97.356 18.206 -14.086 1.00 86.01 ? 104 LEU M N 1 ATOM 9005 C CA . LEU F 3 126 ? 98.569 17.435 -13.878 1.00 89.50 ? 104 LEU M CA 1 ATOM 9006 C C . LEU F 3 126 ? 98.733 16.314 -14.901 1.00 92.82 ? 104 LEU M C 1 ATOM 9007 O O . LEU F 3 126 ? 97.838 15.490 -15.094 1.00 93.00 ? 104 LEU M O 1 ATOM 9008 C CB . LEU F 3 126 ? 98.570 16.868 -12.458 1.00 88.15 ? 104 LEU M CB 1 ATOM 9009 C CG . LEU F 3 126 ? 99.431 15.648 -12.144 1.00 87.51 ? 104 LEU M CG 1 ATOM 9010 C CD1 . LEU F 3 126 ? 99.761 15.652 -10.677 1.00 88.29 ? 104 LEU M CD1 1 ATOM 9011 C CD2 . LEU F 3 126 ? 98.700 14.368 -12.518 1.00 87.00 ? 104 LEU M CD2 1 ATOM 9012 N N . THR F 3 127 ? 99.887 16.301 -15.560 1.00 96.55 ? 105 THR M N 1 ATOM 9013 C CA . THR F 3 127 ? 100.204 15.292 -16.561 1.00 99.65 ? 105 THR M CA 1 ATOM 9014 C C . THR F 3 127 ? 101.339 14.412 -16.066 1.00 102.64 ? 105 THR M C 1 ATOM 9015 O O . THR F 3 127 ? 102.062 14.769 -15.132 1.00 102.50 ? 105 THR M O 1 ATOM 9016 C CB . THR F 3 127 ? 100.652 15.933 -17.894 1.00 98.96 ? 105 THR M CB 1 ATOM 9017 O OG1 . THR F 3 127 ? 101.361 17.148 -17.622 1.00 97.61 ? 105 THR M OG1 1 ATOM 9018 C CG2 . THR F 3 127 ? 99.460 16.219 -18.788 1.00 99.21 ? 105 THR M CG2 1 ATOM 9019 N N . VAL F 3 128 ? 101.485 13.254 -16.694 1.00 105.92 ? 106 VAL M N 1 ATOM 9020 C CA . VAL F 3 128 ? 102.552 12.332 -16.344 1.00 109.02 ? 106 VAL M CA 1 ATOM 9021 C C . VAL F 3 128 ? 103.699 12.629 -17.308 1.00 110.81 ? 106 VAL M C 1 ATOM 9022 O O . VAL F 3 128 ? 103.482 13.180 -18.389 1.00 111.43 ? 106 VAL M O 1 ATOM 9023 C CB . VAL F 3 128 ? 102.107 10.862 -16.517 1.00 109.57 ? 106 VAL M CB 1 ATOM 9024 C CG1 . VAL F 3 128 ? 101.753 10.584 -17.978 1.00 110.09 ? 106 VAL M CG1 1 ATOM 9025 C CG2 . VAL F 3 128 ? 103.211 9.932 -16.049 1.00 110.33 ? 106 VAL M CG2 1 ATOM 9026 N N . LEU F 3 129 ? 104.917 12.276 -16.921 1.00 112.44 ? 107 LEU M N 1 ATOM 9027 C CA . LEU F 3 129 ? 106.061 12.523 -17.782 1.00 113.77 ? 107 LEU M CA 1 ATOM 9028 C C . LEU F 3 129 ? 106.504 11.285 -18.550 1.00 115.16 ? 107 LEU M C 1 ATOM 9029 O O . LEU F 3 129 ? 106.559 10.183 -18.004 1.00 115.51 ? 107 LEU M O 1 ATOM 9030 C CB . LEU F 3 129 ? 107.226 13.076 -16.962 1.00 113.21 ? 107 LEU M CB 1 ATOM 9031 C CG . LEU F 3 129 ? 107.152 14.575 -16.667 1.00 112.97 ? 107 LEU M CG 1 ATOM 9032 C CD1 . LEU F 3 129 ? 107.102 15.327 -17.982 1.00 112.99 ? 107 LEU M CD1 1 ATOM 9033 C CD2 . LEU F 3 129 ? 105.928 14.897 -15.835 1.00 113.38 ? 107 LEU M CD2 1 ATOM 9034 N N . GLY F 3 130 ? 106.813 11.483 -19.827 1.00 116.51 ? 108 GLY M N 1 ATOM 9035 C CA . GLY F 3 130 ? 107.259 10.397 -20.683 1.00 117.84 ? 108 GLY M CA 1 ATOM 9036 C C . GLY F 3 130 ? 107.459 10.926 -22.088 1.00 118.55 ? 108 GLY M C 1 ATOM 9037 O O . GLY F 3 130 ? 106.638 11.707 -22.565 1.00 119.52 ? 108 GLY M O 1 ATOM 9038 N N . GLN F 3 131 ? 108.536 10.515 -22.756 1.00 118.96 ? 109 GLN M N 1 ATOM 9039 C CA . GLN F 3 131 ? 108.816 10.976 -24.117 1.00 119.52 ? 109 GLN M CA 1 ATOM 9040 C C . GLN F 3 131 ? 108.518 12.473 -24.278 1.00 119.49 ? 109 GLN M C 1 ATOM 9041 O O . GLN F 3 131 ? 107.670 12.864 -25.079 1.00 120.76 ? 109 GLN M O 1 ATOM 9042 C CB . GLN F 3 131 ? 107.988 10.156 -25.123 1.00 120.18 ? 109 GLN M CB 1 ATOM 9043 C CG . GLN F 3 131 ? 106.605 9.711 -24.611 1.00 121.09 ? 109 GLN M CG 1 ATOM 9044 C CD . GLN F 3 131 ? 105.434 10.256 -25.430 1.00 121.32 ? 109 GLN M CD 1 ATOM 9045 O OE1 . GLN F 3 131 ? 105.296 11.469 -25.617 1.00 120.96 ? 109 GLN M OE1 1 ATOM 9046 N NE2 . GLN F 3 131 ? 104.578 9.355 -25.908 1.00 120.78 ? 109 GLN M NE2 1 ATOM 9047 N N . PRO F 3 132 ? 109.220 13.332 -23.518 1.00 118.66 ? 110 PRO M N 1 ATOM 9048 C CA . PRO F 3 132 ? 109.025 14.788 -23.571 1.00 117.87 ? 110 PRO M CA 1 ATOM 9049 C C . PRO F 3 132 ? 109.619 15.555 -24.757 1.00 116.80 ? 110 PRO M C 1 ATOM 9050 O O . PRO F 3 132 ? 110.159 16.651 -24.584 1.00 116.21 ? 110 PRO M O 1 ATOM 9051 C CB . PRO F 3 132 ? 109.602 15.251 -22.239 1.00 118.18 ? 110 PRO M CB 1 ATOM 9052 C CG . PRO F 3 132 ? 110.729 14.293 -22.034 1.00 119.06 ? 110 PRO M CG 1 ATOM 9053 C CD . PRO F 3 132 ? 110.114 12.966 -22.405 1.00 118.65 ? 110 PRO M CD 1 ATOM 9054 N N . LYS F 3 133 A 109.501 14.995 -25.957 1.00 115.71 ? 110 LYS M N 1 ATOM 9055 C CA . LYS F 3 133 A 110.023 15.646 -27.155 1.00 115.07 ? 110 LYS M CA 1 ATOM 9056 C C . LYS F 3 133 A 108.956 16.481 -27.863 1.00 114.47 ? 110 LYS M C 1 ATOM 9057 O O . LYS F 3 133 A 108.157 15.962 -28.645 1.00 114.37 ? 110 LYS M O 1 ATOM 9058 C CB . LYS F 3 133 A 110.598 14.596 -28.109 1.00 115.80 ? 110 LYS M CB 1 ATOM 9059 C CG . LYS F 3 133 A 111.791 13.852 -27.520 1.00 116.76 ? 110 LYS M CG 1 ATOM 9060 C CD . LYS F 3 133 A 112.848 14.848 -27.045 1.00 116.90 ? 110 LYS M CD 1 ATOM 9061 C CE . LYS F 3 133 A 113.920 14.201 -26.186 1.00 115.86 ? 110 LYS M CE 1 ATOM 9062 N NZ . LYS F 3 133 A 114.837 15.232 -25.619 1.00 114.97 ? 110 LYS M NZ 1 ATOM 9063 N N . ALA F 3 134 ? 108.966 17.782 -27.586 1.00 113.65 ? 111 ALA M N 1 ATOM 9064 C CA . ALA F 3 134 ? 108.001 18.721 -28.158 1.00 112.69 ? 111 ALA M CA 1 ATOM 9065 C C . ALA F 3 134 ? 108.347 19.229 -29.553 1.00 111.80 ? 111 ALA M C 1 ATOM 9066 O O . ALA F 3 134 ? 109.179 20.123 -29.705 1.00 111.73 ? 111 ALA M O 1 ATOM 9067 C CB . ALA F 3 134 ? 107.833 19.906 -27.225 1.00 113.03 ? 111 ALA M CB 1 ATOM 9068 N N . ALA F 3 135 ? 107.682 18.682 -30.565 1.00 111.27 ? 112 ALA M N 1 ATOM 9069 C CA . ALA F 3 135 ? 107.915 19.090 -31.951 1.00 110.76 ? 112 ALA M CA 1 ATOM 9070 C C . ALA F 3 135 ? 106.733 19.891 -32.510 1.00 110.05 ? 112 ALA M C 1 ATOM 9071 O O . ALA F 3 135 ? 106.141 19.500 -33.520 1.00 109.85 ? 112 ALA M O 1 ATOM 9072 C CB . ALA F 3 135 ? 108.162 17.852 -32.824 1.00 110.30 ? 112 ALA M CB 1 ATOM 9073 N N . PRO F 3 136 ? 106.386 21.030 -31.873 1.00 109.05 ? 113 PRO M N 1 ATOM 9074 C CA . PRO F 3 136 ? 105.263 21.857 -32.338 1.00 108.23 ? 113 PRO M CA 1 ATOM 9075 C C . PRO F 3 136 ? 105.365 22.293 -33.801 1.00 107.28 ? 113 PRO M C 1 ATOM 9076 O O . PRO F 3 136 ? 105.636 23.457 -34.100 1.00 106.65 ? 113 PRO M O 1 ATOM 9077 C CB . PRO F 3 136 ? 105.274 23.037 -31.365 1.00 108.38 ? 113 PRO M CB 1 ATOM 9078 C CG . PRO F 3 136 ? 106.715 23.146 -30.976 1.00 108.63 ? 113 PRO M CG 1 ATOM 9079 C CD . PRO F 3 136 ? 107.106 21.705 -30.777 1.00 108.32 ? 113 PRO M CD 1 ATOM 9080 N N . SER F 3 137 ? 105.135 21.340 -34.701 1.00 106.23 ? 114 SER M N 1 ATOM 9081 C CA . SER F 3 137 ? 105.189 21.571 -36.138 1.00 105.44 ? 114 SER M CA 1 ATOM 9082 C C . SER F 3 137 ? 104.062 22.508 -36.561 1.00 105.44 ? 114 SER M C 1 ATOM 9083 O O . SER F 3 137 ? 103.068 22.071 -37.142 1.00 106.29 ? 114 SER M O 1 ATOM 9084 C CB . SER F 3 137 ? 105.048 20.238 -36.874 1.00 105.27 ? 114 SER M CB 1 ATOM 9085 O OG . SER F 3 137 ? 105.854 19.238 -36.274 1.00 105.35 ? 114 SER M OG 1 ATOM 9086 N N . VAL F 3 138 ? 104.220 23.795 -36.272 1.00 104.84 ? 115 VAL M N 1 ATOM 9087 C CA . VAL F 3 138 ? 103.206 24.787 -36.613 1.00 104.19 ? 115 VAL M CA 1 ATOM 9088 C C . VAL F 3 138 ? 103.099 25.013 -38.118 1.00 103.74 ? 115 VAL M C 1 ATOM 9089 O O . VAL F 3 138 ? 104.078 24.870 -38.846 1.00 103.41 ? 115 VAL M O 1 ATOM 9090 C CB . VAL F 3 138 ? 103.503 26.141 -35.927 1.00 103.87 ? 115 VAL M CB 1 ATOM 9091 C CG1 . VAL F 3 138 ? 104.827 26.681 -36.408 1.00 104.22 ? 115 VAL M CG1 1 ATOM 9092 C CG2 . VAL F 3 138 ? 102.392 27.134 -36.218 1.00 104.23 ? 115 VAL M CG2 1 ATOM 9093 N N . THR F 3 139 ? 101.894 25.354 -38.570 1.00 103.74 ? 116 THR M N 1 ATOM 9094 C CA . THR F 3 139 ? 101.620 25.625 -39.980 1.00 103.36 ? 116 THR M CA 1 ATOM 9095 C C . THR F 3 139 ? 100.568 26.738 -40.055 1.00 103.18 ? 116 THR M C 1 ATOM 9096 O O . THR F 3 139 ? 99.719 26.851 -39.171 1.00 102.79 ? 116 THR M O 1 ATOM 9097 C CB . THR F 3 139 ? 101.085 24.366 -40.712 1.00 103.04 ? 116 THR M CB 1 ATOM 9098 O OG1 . THR F 3 139 ? 102.053 23.310 -40.641 1.00 102.77 ? 116 THR M OG1 1 ATOM 9099 C CG2 . THR F 3 139 ? 100.818 24.680 -42.169 1.00 102.92 ? 116 THR M CG2 1 ATOM 9100 N N . LEU F 3 140 ? 100.629 27.559 -41.101 1.00 103.33 ? 117 LEU M N 1 ATOM 9101 C CA . LEU F 3 140 ? 99.685 28.663 -41.264 1.00 103.30 ? 117 LEU M CA 1 ATOM 9102 C C . LEU F 3 140 ? 99.120 28.704 -42.683 1.00 104.03 ? 117 LEU M C 1 ATOM 9103 O O . LEU F 3 140 ? 99.871 28.708 -43.657 1.00 103.42 ? 117 LEU M O 1 ATOM 9104 C CB . LEU F 3 140 ? 100.382 29.994 -40.953 1.00 102.51 ? 117 LEU M CB 1 ATOM 9105 C CG . LEU F 3 140 ? 99.576 31.244 -40.569 1.00 102.26 ? 117 LEU M CG 1 ATOM 9106 C CD1 . LEU F 3 140 ? 98.448 31.494 -41.556 1.00 102.31 ? 117 LEU M CD1 1 ATOM 9107 C CD2 . LEU F 3 140 ? 99.015 31.069 -39.175 1.00 102.07 ? 117 LEU M CD2 1 ATOM 9108 N N . PHE F 3 141 ? 97.792 28.732 -42.789 1.00 105.46 ? 118 PHE M N 1 ATOM 9109 C CA . PHE F 3 141 ? 97.110 28.794 -44.082 1.00 106.34 ? 118 PHE M CA 1 ATOM 9110 C C . PHE F 3 141 ? 96.360 30.120 -44.195 1.00 106.87 ? 118 PHE M C 1 ATOM 9111 O O . PHE F 3 141 ? 95.519 30.432 -43.355 1.00 106.72 ? 118 PHE M O 1 ATOM 9112 C CB . PHE F 3 141 ? 96.098 27.651 -44.234 1.00 106.71 ? 118 PHE M CB 1 ATOM 9113 C CG . PHE F 3 141 ? 96.715 26.277 -44.284 1.00 107.75 ? 118 PHE M CG 1 ATOM 9114 C CD1 . PHE F 3 141 ? 97.240 25.686 -43.137 1.00 108.20 ? 118 PHE M CD1 1 ATOM 9115 C CD2 . PHE F 3 141 ? 96.738 25.557 -45.474 1.00 107.59 ? 118 PHE M CD2 1 ATOM 9116 C CE1 . PHE F 3 141 ? 97.776 24.395 -43.174 1.00 107.33 ? 118 PHE M CE1 1 ATOM 9117 C CE2 . PHE F 3 141 ? 97.272 24.266 -45.520 1.00 107.88 ? 118 PHE M CE2 1 ATOM 9118 C CZ . PHE F 3 141 ? 97.791 23.686 -44.367 1.00 107.10 ? 118 PHE M CZ 1 ATOM 9119 N N . PRO F 3 142 ? 96.667 30.922 -45.229 1.00 107.69 ? 119 PRO M N 1 ATOM 9120 C CA . PRO F 3 142 ? 96.023 32.220 -45.462 1.00 108.67 ? 119 PRO M CA 1 ATOM 9121 C C . PRO F 3 142 ? 94.551 32.059 -45.846 1.00 110.26 ? 119 PRO M C 1 ATOM 9122 O O . PRO F 3 142 ? 94.068 30.941 -46.034 1.00 110.53 ? 119 PRO M O 1 ATOM 9123 C CB . PRO F 3 142 ? 96.850 32.811 -46.598 1.00 107.93 ? 119 PRO M CB 1 ATOM 9124 C CG . PRO F 3 142 ? 98.194 32.203 -46.387 1.00 108.02 ? 119 PRO M CG 1 ATOM 9125 C CD . PRO F 3 142 ? 97.842 30.772 -46.101 1.00 107.82 ? 119 PRO M CD 1 ATOM 9126 N N . PRO F 3 143 ? 93.820 33.179 -45.981 1.00 111.37 ? 120 PRO M N 1 ATOM 9127 C CA . PRO F 3 143 ? 92.400 33.121 -46.345 1.00 112.35 ? 120 PRO M CA 1 ATOM 9128 C C . PRO F 3 143 ? 92.137 32.421 -47.676 1.00 112.85 ? 120 PRO M C 1 ATOM 9129 O O . PRO F 3 143 ? 92.879 32.605 -48.643 1.00 112.89 ? 120 PRO M O 1 ATOM 9130 C CB . PRO F 3 143 ? 91.990 34.593 -46.366 1.00 112.09 ? 120 PRO M CB 1 ATOM 9131 C CG . PRO F 3 143 ? 93.252 35.282 -46.776 1.00 111.81 ? 120 PRO M CG 1 ATOM 9132 C CD . PRO F 3 143 ? 94.286 34.576 -45.933 1.00 111.46 ? 120 PRO M CD 1 ATOM 9133 N N . SER F 3 144 ? 91.075 31.619 -47.713 1.00 113.53 ? 121 SER M N 1 ATOM 9134 C CA . SER F 3 144 ? 90.699 30.882 -48.916 1.00 113.44 ? 121 SER M CA 1 ATOM 9135 C C . SER F 3 144 ? 90.354 31.822 -50.060 1.00 113.53 ? 121 SER M C 1 ATOM 9136 O O . SER F 3 144 ? 90.045 33.000 -49.852 1.00 113.43 ? 121 SER M O 1 ATOM 9137 C CB . SER F 3 144 ? 89.495 29.979 -48.639 1.00 112.92 ? 121 SER M CB 1 ATOM 9138 O OG . SER F 3 144 ? 89.761 29.081 -47.580 1.00 113.84 ? 121 SER M OG 1 ATOM 9139 N N . SER F 3 145 ? 90.412 31.290 -51.272 1.00 113.56 ? 122 SER M N 1 ATOM 9140 C CA . SER F 3 145 ? 90.091 32.067 -52.455 1.00 113.86 ? 122 SER M CA 1 ATOM 9141 C C . SER F 3 145 ? 88.614 32.429 -52.373 1.00 113.94 ? 122 SER M C 1 ATOM 9142 O O . SER F 3 145 ? 88.237 33.598 -52.480 1.00 113.39 ? 122 SER M O 1 ATOM 9143 C CB . SER F 3 145 ? 90.355 31.233 -53.712 1.00 114.24 ? 122 SER M CB 1 ATOM 9144 O OG . SER F 3 145 ? 89.620 30.016 -53.682 1.00 114.73 ? 122 SER M OG 1 ATOM 9145 N N . GLU F 3 146 ? 87.793 31.402 -52.161 1.00 113.81 ? 123 GLU M N 1 ATOM 9146 C CA . GLU F 3 146 ? 86.346 31.538 -52.064 1.00 113.31 ? 123 GLU M CA 1 ATOM 9147 C C . GLU F 3 146 ? 85.938 32.268 -50.795 1.00 113.87 ? 123 GLU M C 1 ATOM 9148 O O . GLU F 3 146 ? 84.897 32.924 -50.754 1.00 114.07 ? 123 GLU M O 1 ATOM 9149 C CB . GLU F 3 146 ? 85.707 30.153 -52.095 1.00 112.24 ? 123 GLU M CB 1 ATOM 9150 C CG . GLU F 3 146 ? 86.251 29.278 -53.207 1.00 111.84 ? 123 GLU M CG 1 ATOM 9151 C CD . GLU F 3 146 ? 85.753 27.859 -53.117 1.00 111.64 ? 123 GLU M CD 1 ATOM 9152 O OE1 . GLU F 3 146 ? 85.825 27.290 -52.011 1.00 111.28 ? 123 GLU M OE1 1 ATOM 9153 O OE2 . GLU F 3 146 ? 85.300 27.310 -54.145 1.00 111.88 ? 123 GLU M OE2 1 ATOM 9154 N N . GLU F 3 147 ? 86.762 32.152 -49.759 1.00 114.65 ? 124 GLU M N 1 ATOM 9155 C CA . GLU F 3 147 ? 86.482 32.816 -48.494 1.00 115.55 ? 124 GLU M CA 1 ATOM 9156 C C . GLU F 3 147 ? 86.548 34.324 -48.676 1.00 115.63 ? 124 GLU M C 1 ATOM 9157 O O . GLU F 3 147 ? 85.619 35.043 -48.311 1.00 115.13 ? 124 GLU M O 1 ATOM 9158 C CB . GLU F 3 147 ? 87.494 32.387 -47.435 1.00 116.62 ? 124 GLU M CB 1 ATOM 9159 C CG . GLU F 3 147 ? 87.201 32.932 -46.054 1.00 118.49 ? 124 GLU M CG 1 ATOM 9160 C CD . GLU F 3 147 ? 88.289 32.593 -45.062 1.00 119.97 ? 124 GLU M CD 1 ATOM 9161 O OE1 . GLU F 3 147 ? 89.417 33.111 -45.211 1.00 120.15 ? 124 GLU M OE1 1 ATOM 9162 O OE2 . GLU F 3 147 ? 88.018 31.802 -44.137 1.00 121.26 ? 124 GLU M OE2 1 ATOM 9163 N N . LEU F 3 148 ? 87.655 34.793 -49.248 1.00 116.18 ? 125 LEU M N 1 ATOM 9164 C CA . LEU F 3 148 ? 87.865 36.216 -49.494 1.00 116.19 ? 125 LEU M CA 1 ATOM 9165 C C . LEU F 3 148 ? 86.685 36.821 -50.238 1.00 116.21 ? 125 LEU M C 1 ATOM 9166 O O . LEU F 3 148 ? 86.572 38.040 -50.355 1.00 116.25 ? 125 LEU M O 1 ATOM 9167 C CB . LEU F 3 148 ? 89.140 36.426 -50.310 1.00 115.89 ? 125 LEU M CB 1 ATOM 9168 C CG . LEU F 3 148 ? 90.444 36.032 -49.620 1.00 115.88 ? 125 LEU M CG 1 ATOM 9169 C CD1 . LEU F 3 148 ? 91.597 36.171 -50.597 1.00 116.06 ? 125 LEU M CD1 1 ATOM 9170 C CD2 . LEU F 3 148 ? 90.660 36.914 -48.400 1.00 115.62 ? 125 LEU M CD2 1 ATOM 9171 N N . GLN F 3 149 ? 85.809 35.957 -50.741 1.00 116.23 ? 126 GLN M N 1 ATOM 9172 C CA . GLN F 3 149 ? 84.637 36.396 -51.476 1.00 116.53 ? 126 GLN M CA 1 ATOM 9173 C C . GLN F 3 149 ? 83.497 36.752 -50.534 1.00 116.09 ? 126 GLN M C 1 ATOM 9174 O O . GLN F 3 149 ? 82.982 37.869 -50.565 1.00 116.11 ? 126 GLN M O 1 ATOM 9175 C CB . GLN F 3 149 ? 84.189 35.305 -52.452 1.00 117.69 ? 126 GLN M CB 1 ATOM 9176 C CG . GLN F 3 149 ? 85.216 34.998 -53.539 1.00 120.63 ? 126 GLN M CG 1 ATOM 9177 C CD . GLN F 3 149 ? 84.692 34.049 -54.608 1.00 122.18 ? 126 GLN M CD 1 ATOM 9178 O OE1 . GLN F 3 149 ? 83.661 34.309 -55.232 1.00 123.21 ? 126 GLN M OE1 1 ATOM 9179 N NE2 . GLN F 3 149 ? 85.406 32.947 -54.831 1.00 122.70 ? 126 GLN M NE2 1 ATOM 9180 N N . ALA F 3 150 ? 83.112 35.802 -49.689 1.00 115.22 ? 127 ALA M N 1 ATOM 9181 C CA . ALA F 3 150 ? 82.024 36.013 -48.741 1.00 114.05 ? 127 ALA M CA 1 ATOM 9182 C C . ALA F 3 150 ? 82.325 37.097 -47.704 1.00 113.62 ? 127 ALA M C 1 ATOM 9183 O O . ALA F 3 150 ? 81.649 37.175 -46.677 1.00 114.32 ? 127 ALA M O 1 ATOM 9184 C CB . ALA F 3 150 ? 81.694 34.703 -48.041 1.00 113.67 ? 127 ALA M CB 1 ATOM 9185 N N . ASN F 3 151 ? 83.332 37.928 -47.980 1.00 112.26 ? 128 ASN M N 1 ATOM 9186 C CA . ASN F 3 151 ? 83.745 39.021 -47.087 1.00 110.64 ? 128 ASN M CA 1 ATOM 9187 C C . ASN F 3 151 ? 84.473 38.544 -45.834 1.00 109.03 ? 128 ASN M C 1 ATOM 9188 O O . ASN F 3 151 ? 84.393 39.183 -44.782 1.00 108.18 ? 128 ASN M O 1 ATOM 9189 C CB . ASN F 3 151 ? 82.541 39.874 -46.658 1.00 111.43 ? 128 ASN M CB 1 ATOM 9190 C CG . ASN F 3 151 ? 81.939 40.662 -47.804 1.00 111.59 ? 128 ASN M CG 1 ATOM 9191 O OD1 . ASN F 3 151 ? 82.649 41.335 -48.553 1.00 111.87 ? 128 ASN M OD1 1 ATOM 9192 N ND2 . ASN F 3 151 ? 80.620 40.594 -47.938 1.00 111.33 ? 128 ASN M ND2 1 ATOM 9193 N N . LYS F 3 152 ? 85.188 37.428 -45.948 1.00 107.39 ? 129 LYS M N 1 ATOM 9194 C CA . LYS F 3 152 ? 85.923 36.872 -44.816 1.00 105.34 ? 129 LYS M CA 1 ATOM 9195 C C . LYS F 3 152 ? 87.429 36.818 -45.036 1.00 103.57 ? 129 LYS M C 1 ATOM 9196 O O . LYS F 3 152 ? 87.921 37.021 -46.144 1.00 102.70 ? 129 LYS M O 1 ATOM 9197 C CB . LYS F 3 152 ? 85.406 35.466 -44.486 1.00 105.49 ? 129 LYS M CB 1 ATOM 9198 C CG . LYS F 3 152 ? 84.123 35.445 -43.659 1.00 105.49 ? 129 LYS M CG 1 ATOM 9199 C CD . LYS F 3 152 ? 82.992 36.200 -44.339 1.00 104.96 ? 129 LYS M CD 1 ATOM 9200 C CE . LYS F 3 152 ? 81.756 36.269 -43.457 1.00 105.23 ? 129 LYS M CE 1 ATOM 9201 N NZ . LYS F 3 152 ? 81.201 34.919 -43.163 1.00 106.26 ? 129 LYS M NZ 1 ATOM 9202 N N . ALA F 3 153 ? 88.154 36.543 -43.959 1.00 102.31 ? 130 ALA M N 1 ATOM 9203 C CA . ALA F 3 153 ? 89.604 36.450 -44.011 1.00 101.79 ? 130 ALA M CA 1 ATOM 9204 C C . ALA F 3 153 ? 90.110 35.608 -42.834 1.00 101.13 ? 130 ALA M C 1 ATOM 9205 O O . ALA F 3 153 ? 91.033 35.999 -42.117 1.00 101.45 ? 130 ALA M O 1 ATOM 9206 C CB . ALA F 3 153 ? 90.218 37.851 -43.980 1.00 100.93 ? 130 ALA M CB 1 ATOM 9207 N N . THR F 3 154 ? 89.502 34.442 -42.644 1.00 99.87 ? 131 THR M N 1 ATOM 9208 C CA . THR F 3 154 ? 89.886 33.558 -41.552 1.00 98.49 ? 131 THR M CA 1 ATOM 9209 C C . THR F 3 154 ? 91.311 33.041 -41.693 1.00 98.08 ? 131 THR M C 1 ATOM 9210 O O . THR F 3 154 ? 91.649 32.372 -42.670 1.00 97.30 ? 131 THR M O 1 ATOM 9211 C CB . THR F 3 154 ? 88.940 32.345 -41.455 1.00 97.79 ? 131 THR M CB 1 ATOM 9212 O OG1 . THR F 3 154 ? 87.598 32.797 -41.232 1.00 97.11 ? 131 THR M OG1 1 ATOM 9213 C CG2 . THR F 3 154 ? 89.359 31.438 -40.312 1.00 97.11 ? 131 THR M CG2 1 ATOM 9214 N N . LEU F 3 155 ? 92.143 33.361 -40.709 1.00 97.73 ? 132 LEU M N 1 ATOM 9215 C CA . LEU F 3 155 ? 93.525 32.906 -40.703 1.00 97.87 ? 132 LEU M CA 1 ATOM 9216 C C . LEU F 3 155 ? 93.665 31.706 -39.773 1.00 98.12 ? 132 LEU M C 1 ATOM 9217 O O . LEU F 3 155 ? 93.345 31.783 -38.588 1.00 97.50 ? 132 LEU M O 1 ATOM 9218 C CB . LEU F 3 155 ? 94.458 34.030 -40.253 1.00 97.35 ? 132 LEU M CB 1 ATOM 9219 C CG . LEU F 3 155 ? 94.904 35.012 -41.339 1.00 97.07 ? 132 LEU M CG 1 ATOM 9220 C CD1 . LEU F 3 155 ? 95.586 36.218 -40.711 1.00 96.49 ? 132 LEU M CD1 1 ATOM 9221 C CD2 . LEU F 3 155 ? 95.845 34.299 -42.301 1.00 96.65 ? 132 LEU M CD2 1 ATOM 9222 N N . VAL F 3 156 ? 94.141 30.597 -40.329 1.00 98.75 ? 133 VAL M N 1 ATOM 9223 C CA . VAL F 3 156 ? 94.322 29.359 -39.583 1.00 99.48 ? 133 VAL M CA 1 ATOM 9224 C C . VAL F 3 156 ? 95.783 29.125 -39.242 1.00 99.92 ? 133 VAL M C 1 ATOM 9225 O O . VAL F 3 156 ? 96.670 29.497 -40.001 1.00 100.90 ? 133 VAL M O 1 ATOM 9226 C CB . VAL F 3 156 ? 93.839 28.141 -40.400 1.00 100.09 ? 133 VAL M CB 1 ATOM 9227 C CG1 . VAL F 3 156 ? 94.046 26.861 -39.607 1.00 99.88 ? 133 VAL M CG1 1 ATOM 9228 C CG2 . VAL F 3 156 ? 92.374 28.311 -40.777 1.00 101.17 ? 133 VAL M CG2 1 ATOM 9229 N N . CYS F 3 157 ? 96.022 28.509 -38.092 1.00 100.23 ? 134 CYS M N 1 ATOM 9230 C CA . CYS F 3 157 ? 97.369 28.184 -37.647 1.00 100.49 ? 134 CYS M CA 1 ATOM 9231 C C . CYS F 3 157 ? 97.252 26.786 -37.064 1.00 99.81 ? 134 CYS M C 1 ATOM 9232 O O . CYS F 3 157 ? 96.845 26.618 -35.916 1.00 100.52 ? 134 CYS M O 1 ATOM 9233 C CB . CYS F 3 157 ? 97.844 29.168 -36.573 1.00 103.01 ? 134 CYS M CB 1 ATOM 9234 S SG . CYS F 3 157 ? 99.627 29.059 -36.189 1.00 106.48 ? 134 CYS M SG 1 ATOM 9235 N N . LEU F 3 158 ? 97.596 25.784 -37.868 1.00 98.74 ? 135 LEU M N 1 ATOM 9236 C CA . LEU F 3 158 ? 97.501 24.387 -37.454 1.00 97.47 ? 135 LEU M CA 1 ATOM 9237 C C . LEU F 3 158 ? 98.721 23.835 -36.714 1.00 96.71 ? 135 LEU M C 1 ATOM 9238 O O . LEU F 3 158 ? 99.485 23.035 -37.258 1.00 96.46 ? 135 LEU M O 1 ATOM 9239 C CB . LEU F 3 158 ? 97.206 23.512 -38.677 1.00 96.89 ? 135 LEU M CB 1 ATOM 9240 C CG . LEU F 3 158 ? 95.922 23.846 -39.441 1.00 96.58 ? 135 LEU M CG 1 ATOM 9241 C CD1 . LEU F 3 158 ? 95.788 22.929 -40.645 1.00 96.05 ? 135 LEU M CD1 1 ATOM 9242 C CD2 . LEU F 3 158 ? 94.724 23.697 -38.508 1.00 97.27 ? 135 LEU M CD2 1 ATOM 9243 N N . ILE F 3 159 ? 98.890 24.256 -35.466 1.00 95.70 ? 136 ILE M N 1 ATOM 9244 C CA . ILE F 3 159 ? 100.003 23.788 -34.653 1.00 94.86 ? 136 ILE M CA 1 ATOM 9245 C C . ILE F 3 159 ? 99.830 22.289 -34.378 1.00 94.11 ? 136 ILE M C 1 ATOM 9246 O O . ILE F 3 159 ? 99.135 21.888 -33.447 1.00 93.50 ? 136 ILE M O 1 ATOM 9247 C CB . ILE F 3 159 ? 100.083 24.602 -33.337 1.00 94.44 ? 136 ILE M CB 1 ATOM 9248 C CG1 . ILE F 3 159 ? 100.870 23.827 -32.284 1.00 94.71 ? 136 ILE M CG1 1 ATOM 9249 C CG2 . ILE F 3 159 ? 98.696 24.971 -32.872 1.00 93.45 ? 136 ILE M CG2 1 ATOM 9250 C CD1 . ILE F 3 159 ? 101.035 24.570 -30.988 1.00 96.00 ? 136 ILE M CD1 1 ATOM 9251 N N . SER F 3 160 ? 100.481 21.478 -35.211 1.00 93.90 ? 137 SER M N 1 ATOM 9252 C CA . SER F 3 160 ? 100.412 20.019 -35.148 1.00 94.45 ? 137 SER M CA 1 ATOM 9253 C C . SER F 3 160 ? 100.726 19.326 -33.823 1.00 94.95 ? 137 SER M C 1 ATOM 9254 O O . SER F 3 160 ? 100.333 19.801 -32.760 1.00 95.65 ? 137 SER M O 1 ATOM 9255 C CB . SER F 3 160 ? 101.286 19.425 -36.250 1.00 94.57 ? 137 SER M CB 1 ATOM 9256 O OG . SER F 3 160 ? 100.851 19.868 -37.523 1.00 94.57 ? 137 SER M OG 1 ATOM 9257 N N . ASP F 3 161 ? 101.429 18.195 -33.898 1.00 95.22 ? 138 ASP M N 1 ATOM 9258 C CA . ASP F 3 161 ? 101.760 17.404 -32.710 1.00 95.73 ? 138 ASP M CA 1 ATOM 9259 C C . ASP F 3 161 ? 102.978 17.832 -31.893 1.00 95.84 ? 138 ASP M C 1 ATOM 9260 O O . ASP F 3 161 ? 103.929 18.393 -32.422 1.00 95.29 ? 138 ASP M O 1 ATOM 9261 C CB . ASP F 3 161 ? 101.871 15.918 -33.089 1.00 95.63 ? 138 ASP M CB 1 ATOM 9262 C CG . ASP F 3 161 ? 102.882 15.658 -34.187 1.00 95.14 ? 138 ASP M CG 1 ATOM 9263 O OD1 . ASP F 3 161 ? 102.949 16.450 -35.150 1.00 94.60 ? 138 ASP M OD1 1 ATOM 9264 O OD2 . ASP F 3 161 ? 103.599 14.641 -34.095 1.00 95.33 ? 138 ASP M OD2 1 ATOM 9265 N N . PHE F 3 162 ? 102.925 17.555 -30.591 1.00 96.99 ? 139 PHE M N 1 ATOM 9266 C CA . PHE F 3 162 ? 103.988 17.918 -29.654 1.00 97.86 ? 139 PHE M CA 1 ATOM 9267 C C . PHE F 3 162 ? 103.828 17.233 -28.282 1.00 99.20 ? 139 PHE M C 1 ATOM 9268 O O . PHE F 3 162 ? 103.105 16.241 -28.159 1.00 99.62 ? 139 PHE M O 1 ATOM 9269 C CB . PHE F 3 162 ? 104.005 19.440 -29.484 1.00 97.35 ? 139 PHE M CB 1 ATOM 9270 C CG . PHE F 3 162 ? 102.639 20.046 -29.291 1.00 96.86 ? 139 PHE M CG 1 ATOM 9271 C CD1 . PHE F 3 162 ? 101.919 19.825 -28.124 1.00 97.39 ? 139 PHE M CD1 1 ATOM 9272 C CD2 . PHE F 3 162 ? 102.067 20.829 -30.286 1.00 96.96 ? 139 PHE M CD2 1 ATOM 9273 C CE1 . PHE F 3 162 ? 100.647 20.376 -27.952 1.00 97.52 ? 139 PHE M CE1 1 ATOM 9274 C CE2 . PHE F 3 162 ? 100.796 21.382 -30.122 1.00 96.86 ? 139 PHE M CE2 1 ATOM 9275 C CZ . PHE F 3 162 ? 100.087 21.155 -28.955 1.00 96.88 ? 139 PHE M CZ 1 ATOM 9276 N N . PHE F 3 163 ? 104.503 17.765 -27.260 1.00 99.71 ? 140 PHE M N 1 ATOM 9277 C CA . PHE F 3 163 ? 104.447 17.213 -25.901 1.00 100.49 ? 140 PHE M CA 1 ATOM 9278 C C . PHE F 3 163 ? 105.372 18.042 -25.020 1.00 101.97 ? 140 PHE M C 1 ATOM 9279 O O . PHE F 3 163 ? 106.483 18.353 -25.422 1.00 101.56 ? 140 PHE M O 1 ATOM 9280 C CB . PHE F 3 163 ? 104.921 15.753 -25.898 1.00 99.72 ? 140 PHE M CB 1 ATOM 9281 C CG . PHE F 3 163 ? 104.677 15.026 -24.598 1.00 98.94 ? 140 PHE M CG 1 ATOM 9282 C CD1 . PHE F 3 163 ? 103.873 13.889 -24.566 1.00 98.61 ? 140 PHE M CD1 1 ATOM 9283 C CD2 . PHE F 3 163 ? 105.247 15.469 -23.410 1.00 98.41 ? 140 PHE M CD2 1 ATOM 9284 C CE1 . PHE F 3 163 ? 103.639 13.207 -23.372 1.00 97.14 ? 140 PHE M CE1 1 ATOM 9285 C CE2 . PHE F 3 163 ? 105.018 14.795 -22.210 1.00 97.94 ? 140 PHE M CE2 1 ATOM 9286 C CZ . PHE F 3 163 ? 104.211 13.662 -22.193 1.00 97.39 ? 140 PHE M CZ 1 ATOM 9287 N N . PRO F 3 164 ? 104.934 18.402 -23.801 1.00 104.06 ? 141 PRO M N 1 ATOM 9288 C CA . PRO F 3 164 ? 103.639 18.101 -23.181 1.00 105.91 ? 141 PRO M CA 1 ATOM 9289 C C . PRO F 3 164 ? 102.469 18.936 -23.707 1.00 107.53 ? 141 PRO M C 1 ATOM 9290 O O . PRO F 3 164 ? 102.662 19.985 -24.325 1.00 107.55 ? 141 PRO M O 1 ATOM 9291 C CB . PRO F 3 164 ? 103.912 18.340 -21.696 1.00 105.23 ? 141 PRO M CB 1 ATOM 9292 C CG . PRO F 3 164 ? 104.899 19.451 -21.724 1.00 104.11 ? 141 PRO M CG 1 ATOM 9293 C CD . PRO F 3 164 ? 105.845 19.013 -22.817 1.00 103.74 ? 141 PRO M CD 1 ATOM 9294 N N . GLY F 3 165 ? 101.256 18.455 -23.444 1.00 109.16 ? 142 GLY M N 1 ATOM 9295 C CA . GLY F 3 165 ? 100.057 19.135 -23.900 1.00 110.92 ? 142 GLY M CA 1 ATOM 9296 C C . GLY F 3 165 ? 99.790 20.485 -23.268 1.00 112.23 ? 142 GLY M C 1 ATOM 9297 O O . GLY F 3 165 ? 99.132 20.578 -22.229 1.00 112.33 ? 142 GLY M O 1 ATOM 9298 N N . ALA F 3 166 ? 100.299 21.531 -23.911 1.00 113.28 ? 143 ALA M N 1 ATOM 9299 C CA . ALA F 3 166 ? 100.126 22.900 -23.447 1.00 114.74 ? 143 ALA M CA 1 ATOM 9300 C C . ALA F 3 166 ? 101.039 23.810 -24.247 1.00 115.83 ? 143 ALA M C 1 ATOM 9301 O O . ALA F 3 166 ? 102.221 23.518 -24.409 1.00 116.15 ? 143 ALA M O 1 ATOM 9302 C CB . ALA F 3 166 ? 100.461 23.006 -21.968 1.00 114.87 ? 143 ALA M CB 1 ATOM 9303 N N . VAL F 3 167 ? 100.481 24.903 -24.756 1.00 117.46 ? 144 VAL M N 1 ATOM 9304 C CA . VAL F 3 167 ? 101.239 25.881 -25.534 1.00 119.39 ? 144 VAL M CA 1 ATOM 9305 C C . VAL F 3 167 ? 100.603 27.261 -25.360 1.00 120.85 ? 144 VAL M C 1 ATOM 9306 O O . VAL F 3 167 ? 99.924 27.522 -24.363 1.00 121.06 ? 144 VAL M O 1 ATOM 9307 C CB . VAL F 3 167 ? 101.261 25.532 -27.050 1.00 119.29 ? 144 VAL M CB 1 ATOM 9308 C CG1 . VAL F 3 167 ? 101.797 24.126 -27.261 1.00 119.11 ? 144 VAL M CG1 1 ATOM 9309 C CG2 . VAL F 3 167 ? 99.870 25.664 -27.641 1.00 119.81 ? 144 VAL M CG2 1 ATOM 9310 N N . THR F 3 168 ? 100.826 28.139 -26.332 1.00 121.95 ? 145 THR M N 1 ATOM 9311 C CA . THR F 3 168 ? 100.267 29.484 -26.296 1.00 123.42 ? 145 THR M CA 1 ATOM 9312 C C . THR F 3 168 ? 100.361 30.066 -27.694 1.00 124.45 ? 145 THR M C 1 ATOM 9313 O O . THR F 3 168 ? 101.108 29.558 -28.526 1.00 125.03 ? 145 THR M O 1 ATOM 9314 C CB . THR F 3 168 ? 101.041 30.388 -25.321 1.00 123.70 ? 145 THR M CB 1 ATOM 9315 O OG1 . THR F 3 168 ? 101.020 29.806 -24.012 1.00 124.08 ? 145 THR M OG1 1 ATOM 9316 C CG2 . THR F 3 168 ? 100.406 31.773 -25.258 1.00 123.98 ? 145 THR M CG2 1 ATOM 9317 N N . VAL F 3 169 ? 99.603 31.125 -27.957 1.00 125.71 ? 146 VAL M N 1 ATOM 9318 C CA . VAL F 3 169 ? 99.616 31.753 -29.272 1.00 127.15 ? 146 VAL M CA 1 ATOM 9319 C C . VAL F 3 169 ? 99.523 33.273 -29.173 1.00 128.43 ? 146 VAL M C 1 ATOM 9320 O O . VAL F 3 169 ? 99.105 33.813 -28.150 1.00 128.80 ? 146 VAL M O 1 ATOM 9321 C CB . VAL F 3 169 ? 98.444 31.238 -30.141 1.00 126.72 ? 146 VAL M CB 1 ATOM 9322 C CG1 . VAL F 3 169 ? 98.529 31.824 -31.540 1.00 126.59 ? 146 VAL M CG1 1 ATOM 9323 C CG2 . VAL F 3 169 ? 98.470 29.720 -30.203 1.00 126.43 ? 146 VAL M CG2 1 ATOM 9324 N N . ALA F 3 170 ? 99.921 33.952 -30.245 1.00 129.66 ? 147 ALA M N 1 ATOM 9325 C CA . ALA F 3 170 ? 99.881 35.407 -30.306 1.00 130.69 ? 147 ALA M CA 1 ATOM 9326 C C . ALA F 3 170 ? 100.047 35.872 -31.750 1.00 131.76 ? 147 ALA M C 1 ATOM 9327 O O . ALA F 3 170 ? 101.096 35.668 -32.360 1.00 131.69 ? 147 ALA M O 1 ATOM 9328 C CB . ALA F 3 170 ? 100.980 35.996 -29.435 1.00 130.50 ? 147 ALA M CB 1 ATOM 9329 N N . TRP F 3 171 ? 99.003 36.491 -32.294 1.00 133.43 ? 148 TRP M N 1 ATOM 9330 C CA . TRP F 3 171 ? 99.031 36.985 -33.667 1.00 135.01 ? 148 TRP M CA 1 ATOM 9331 C C . TRP F 3 171 ? 99.353 38.475 -33.697 1.00 135.72 ? 148 TRP M C 1 ATOM 9332 O O . TRP F 3 171 ? 99.041 39.207 -32.757 1.00 135.74 ? 148 TRP M O 1 ATOM 9333 C CB . TRP F 3 171 ? 97.682 36.737 -34.352 1.00 135.52 ? 148 TRP M CB 1 ATOM 9334 C CG . TRP F 3 171 ? 97.291 35.289 -34.423 1.00 136.16 ? 148 TRP M CG 1 ATOM 9335 C CD1 . TRP F 3 171 ? 97.119 34.437 -33.373 1.00 136.38 ? 148 TRP M CD1 1 ATOM 9336 C CD2 . TRP F 3 171 ? 97.002 34.532 -35.604 1.00 136.22 ? 148 TRP M CD2 1 ATOM 9337 N NE1 . TRP F 3 171 ? 96.737 33.197 -33.822 1.00 136.38 ? 148 TRP M NE1 1 ATOM 9338 C CE2 . TRP F 3 171 ? 96.658 33.227 -35.190 1.00 136.40 ? 148 TRP M CE2 1 ATOM 9339 C CE3 . TRP F 3 171 ? 97.000 34.827 -36.973 1.00 136.26 ? 148 TRP M CE3 1 ATOM 9340 C CZ2 . TRP F 3 171 ? 96.313 32.217 -36.097 1.00 136.54 ? 148 TRP M CZ2 1 ATOM 9341 C CZ3 . TRP F 3 171 ? 96.657 33.822 -37.876 1.00 136.31 ? 148 TRP M CZ3 1 ATOM 9342 C CH2 . TRP F 3 171 ? 96.319 32.534 -37.432 1.00 136.28 ? 148 TRP M CH2 1 ATOM 9343 N N . LYS F 3 172 ? 99.969 38.923 -34.785 1.00 136.54 ? 149 LYS M N 1 ATOM 9344 C CA . LYS F 3 172 ? 100.338 40.324 -34.912 1.00 137.40 ? 149 LYS M CA 1 ATOM 9345 C C . LYS F 3 172 ? 100.456 40.807 -36.353 1.00 137.38 ? 149 LYS M C 1 ATOM 9346 O O . LYS F 3 172 ? 100.786 40.038 -37.254 1.00 137.32 ? 149 LYS M O 1 ATOM 9347 C CB . LYS F 3 172 ? 101.663 40.569 -34.192 1.00 138.42 ? 149 LYS M CB 1 ATOM 9348 C CG . LYS F 3 172 ? 102.760 39.579 -34.552 1.00 139.75 ? 149 LYS M CG 1 ATOM 9349 C CD . LYS F 3 172 ? 104.099 39.996 -33.959 1.00 140.84 ? 149 LYS M CD 1 ATOM 9350 C CE . LYS F 3 172 ? 104.030 40.139 -32.445 1.00 141.27 ? 149 LYS M CE 1 ATOM 9351 N NZ . LYS F 3 172 ? 105.333 40.589 -31.877 1.00 141.78 ? 149 LYS M NZ 1 ATOM 9352 N N . ALA F 3 173 ? 100.182 42.092 -36.555 1.00 137.51 ? 150 ALA M N 1 ATOM 9353 C CA . ALA F 3 173 ? 100.280 42.712 -37.870 1.00 138.04 ? 150 ALA M CA 1 ATOM 9354 C C . ALA F 3 173 ? 101.589 43.506 -37.898 1.00 138.63 ? 150 ALA M C 1 ATOM 9355 O O . ALA F 3 173 ? 101.715 44.531 -37.222 1.00 138.96 ? 150 ALA M O 1 ATOM 9356 C CB . ALA F 3 173 ? 99.089 43.636 -38.105 1.00 137.59 ? 150 ALA M CB 1 ATOM 9357 N N . ASP F 3 174 ? 102.554 43.017 -38.680 1.00 138.75 ? 151 ASP M N 1 ATOM 9358 C CA . ASP F 3 174 ? 103.882 43.629 -38.807 1.00 138.62 ? 151 ASP M CA 1 ATOM 9359 C C . ASP F 3 174 ? 104.699 43.284 -37.562 1.00 138.81 ? 151 ASP M C 1 ATOM 9360 O O . ASP F 3 174 ? 105.496 42.343 -37.560 1.00 138.38 ? 151 ASP M O 1 ATOM 9361 C CB . ASP F 3 174 ? 103.784 45.156 -38.941 1.00 138.01 ? 151 ASP M CB 1 ATOM 9362 C CG . ASP F 3 174 ? 102.883 45.590 -40.078 1.00 137.22 ? 151 ASP M CG 1 ATOM 9363 O OD1 . ASP F 3 174 ? 103.087 45.115 -41.215 1.00 136.77 ? 151 ASP M OD1 1 ATOM 9364 O OD2 . ASP F 3 174 ? 101.975 46.414 -39.835 1.00 136.68 ? 151 ASP M OD2 1 ATOM 9365 N N . GLY F 3 175 ? 104.483 44.064 -36.507 1.00 139.19 ? 152 GLY M N 1 ATOM 9366 C CA . GLY F 3 175 ? 105.167 43.855 -35.245 1.00 138.88 ? 152 GLY M CA 1 ATOM 9367 C C . GLY F 3 175 ? 104.170 44.070 -34.122 1.00 138.95 ? 152 GLY M C 1 ATOM 9368 O O . GLY F 3 175 ? 104.241 43.419 -33.079 1.00 138.79 ? 152 GLY M O 1 ATOM 9369 N N . ALA F 3 176 ? 103.229 44.986 -34.347 1.00 138.86 ? 153 ALA M N 1 ATOM 9370 C CA . ALA F 3 176 ? 102.192 45.304 -33.368 1.00 138.81 ? 153 ALA M CA 1 ATOM 9371 C C . ALA F 3 176 ? 101.125 44.208 -33.356 1.00 138.69 ? 153 ALA M C 1 ATOM 9372 O O . ALA F 3 176 ? 100.342 44.084 -34.300 1.00 138.73 ? 153 ALA M O 1 ATOM 9373 C CB . ALA F 3 176 ? 101.558 46.650 -33.703 1.00 138.62 ? 153 ALA M CB 1 ATOM 9374 N N . PRO F 3 177 ? 101.078 43.403 -32.277 1.00 138.34 ? 154 PRO M N 1 ATOM 9375 C CA . PRO F 3 177 ? 100.118 42.304 -32.114 1.00 137.82 ? 154 PRO M CA 1 ATOM 9376 C C . PRO F 3 177 ? 98.652 42.705 -31.984 1.00 137.22 ? 154 PRO M C 1 ATOM 9377 O O . PRO F 3 177 ? 98.305 43.604 -31.217 1.00 137.33 ? 154 PRO M O 1 ATOM 9378 C CB . PRO F 3 177 ? 100.634 41.584 -30.871 1.00 137.85 ? 154 PRO M CB 1 ATOM 9379 C CG . PRO F 3 177 ? 101.207 42.696 -30.066 1.00 137.95 ? 154 PRO M CG 1 ATOM 9380 C CD . PRO F 3 177 ? 101.971 43.484 -31.107 1.00 138.21 ? 154 PRO M CD 1 ATOM 9381 N N . VAL F 3 178 ? 97.797 42.021 -32.743 1.00 136.26 ? 155 VAL M N 1 ATOM 9382 C CA . VAL F 3 178 ? 96.362 42.283 -32.717 1.00 135.00 ? 155 VAL M CA 1 ATOM 9383 C C . VAL F 3 178 ? 95.764 41.689 -31.452 1.00 134.21 ? 155 VAL M C 1 ATOM 9384 O O . VAL F 3 178 ? 96.096 40.568 -31.067 1.00 133.96 ? 155 VAL M O 1 ATOM 9385 C CB . VAL F 3 178 ? 95.647 41.657 -33.932 1.00 134.81 ? 155 VAL M CB 1 ATOM 9386 C CG1 . VAL F 3 178 ? 96.068 42.363 -35.210 1.00 134.60 ? 155 VAL M CG1 1 ATOM 9387 C CG2 . VAL F 3 178 ? 95.970 40.176 -34.011 1.00 134.63 ? 155 VAL M CG2 1 ATOM 9388 N N . LYS F 3 179 ? 94.882 42.449 -30.810 1.00 133.50 ? 156 LYS M N 1 ATOM 9389 C CA . LYS F 3 179 ? 94.233 42.008 -29.580 1.00 132.36 ? 156 LYS M CA 1 ATOM 9390 C C . LYS F 3 179 ? 93.352 40.780 -29.801 1.00 130.58 ? 156 LYS M C 1 ATOM 9391 O O . LYS F 3 179 ? 93.753 39.837 -30.485 1.00 130.57 ? 156 LYS M O 1 ATOM 9392 C CB . LYS F 3 179 ? 93.404 43.152 -28.977 1.00 133.17 ? 156 LYS M CB 1 ATOM 9393 C CG . LYS F 3 179 ? 94.237 44.264 -28.331 1.00 134.34 ? 156 LYS M CG 1 ATOM 9394 C CD . LYS F 3 179 ? 95.076 45.044 -29.346 1.00 134.44 ? 156 LYS M CD 1 ATOM 9395 C CE . LYS F 3 179 ? 94.213 45.964 -30.193 1.00 134.53 ? 156 LYS M CE 1 ATOM 9396 N NZ . LYS F 3 179 ? 93.494 46.963 -29.350 1.00 134.95 ? 156 LYS M NZ 1 ATOM 9397 N N . ALA F 3 180 ? 92.155 40.795 -29.220 1.00 128.36 ? 157 ALA M N 1 ATOM 9398 C CA . ALA F 3 180 ? 91.219 39.678 -29.338 1.00 125.89 ? 157 ALA M CA 1 ATOM 9399 C C . ALA F 3 180 ? 90.937 39.278 -30.788 1.00 123.85 ? 157 ALA M C 1 ATOM 9400 O O . ALA F 3 180 ? 91.670 39.650 -31.709 1.00 123.92 ? 157 ALA M O 1 ATOM 9401 C CB . ALA F 3 180 ? 89.909 40.017 -28.623 1.00 125.94 ? 157 ALA M CB 1 ATOM 9402 N N . GLY F 3 181 ? 89.864 38.517 -30.985 1.00 120.84 ? 158 GLY M N 1 ATOM 9403 C CA . GLY F 3 181 ? 89.516 38.071 -32.320 1.00 116.46 ? 158 GLY M CA 1 ATOM 9404 C C . GLY F 3 181 ? 90.358 36.867 -32.680 1.00 113.40 ? 158 GLY M C 1 ATOM 9405 O O . GLY F 3 181 ? 90.213 36.289 -33.755 1.00 112.57 ? 158 GLY M O 1 ATOM 9406 N N . VAL F 3 182 ? 91.247 36.492 -31.767 1.00 110.79 ? 159 VAL M N 1 ATOM 9407 C CA . VAL F 3 182 ? 92.125 35.351 -31.974 1.00 108.93 ? 159 VAL M CA 1 ATOM 9408 C C . VAL F 3 182 ? 91.730 34.174 -31.083 1.00 107.75 ? 159 VAL M C 1 ATOM 9409 O O . VAL F 3 182 ? 92.509 33.720 -30.242 1.00 108.40 ? 159 VAL M O 1 ATOM 9410 C CB . VAL F 3 182 ? 93.607 35.726 -31.704 1.00 108.83 ? 159 VAL M CB 1 ATOM 9411 C CG1 . VAL F 3 182 ? 93.757 36.313 -30.314 1.00 108.89 ? 159 VAL M CG1 1 ATOM 9412 C CG2 . VAL F 3 182 ? 94.491 34.501 -31.857 1.00 108.07 ? 159 VAL M CG2 1 ATOM 9413 N N . GLU F 3 183 ? 90.510 33.684 -31.268 1.00 105.34 ? 160 GLU M N 1 ATOM 9414 C CA . GLU F 3 183 ? 90.031 32.551 -30.491 1.00 102.45 ? 160 GLU M CA 1 ATOM 9415 C C . GLU F 3 183 ? 90.932 31.364 -30.828 1.00 100.77 ? 160 GLU M C 1 ATOM 9416 O O . GLU F 3 183 ? 91.178 31.077 -32.000 1.00 99.31 ? 160 GLU M O 1 ATOM 9417 C CB . GLU F 3 183 ? 88.582 32.243 -30.862 1.00 102.64 ? 160 GLU M CB 1 ATOM 9418 C CG . GLU F 3 183 ? 87.923 31.219 -29.967 1.00 102.72 ? 160 GLU M CG 1 ATOM 9419 C CD . GLU F 3 183 ? 87.823 31.681 -28.531 1.00 102.36 ? 160 GLU M CD 1 ATOM 9420 O OE1 . GLU F 3 183 ? 87.093 32.660 -28.270 1.00 102.25 ? 160 GLU M OE1 1 ATOM 9421 O OE2 . GLU F 3 183 ? 88.475 31.062 -27.665 1.00 102.25 ? 160 GLU M OE2 1 ATOM 9422 N N . THR F 3 184 ? 91.426 30.682 -29.799 1.00 99.27 ? 161 THR M N 1 ATOM 9423 C CA . THR F 3 184 ? 92.320 29.544 -29.997 1.00 98.10 ? 161 THR M CA 1 ATOM 9424 C C . THR F 3 184 ? 91.849 28.277 -29.278 1.00 97.07 ? 161 THR M C 1 ATOM 9425 O O . THR F 3 184 ? 91.500 28.315 -28.099 1.00 96.81 ? 161 THR M O 1 ATOM 9426 C CB . THR F 3 184 ? 93.741 29.890 -29.510 1.00 98.33 ? 161 THR M CB 1 ATOM 9427 O OG1 . THR F 3 184 ? 94.196 31.075 -30.174 1.00 98.53 ? 161 THR M OG1 1 ATOM 9428 C CG2 . THR F 3 184 ? 94.704 28.749 -29.802 1.00 97.95 ? 161 THR M CG2 1 ATOM 9429 N N . THR F 3 185 ? 91.855 27.155 -29.994 1.00 96.02 ? 162 THR M N 1 ATOM 9430 C CA . THR F 3 185 ? 91.424 25.878 -29.429 1.00 94.93 ? 162 THR M CA 1 ATOM 9431 C C . THR F 3 185 ? 92.421 25.393 -28.385 1.00 93.98 ? 162 THR M C 1 ATOM 9432 O O . THR F 3 185 ? 93.596 25.750 -28.429 1.00 93.86 ? 162 THR M O 1 ATOM 9433 C CB . THR F 3 185 ? 91.279 24.783 -30.525 1.00 94.91 ? 162 THR M CB 1 ATOM 9434 O OG1 . THR F 3 185 ? 92.569 24.261 -30.867 1.00 94.42 ? 162 THR M OG1 1 ATOM 9435 C CG2 . THR F 3 185 ? 90.625 25.362 -31.779 1.00 94.52 ? 162 THR M CG2 1 ATOM 9436 N N . LYS F 3 186 ? 91.948 24.585 -27.444 1.00 93.41 ? 163 LYS M N 1 ATOM 9437 C CA . LYS F 3 186 ? 92.813 24.056 -26.396 1.00 93.21 ? 163 LYS M CA 1 ATOM 9438 C C . LYS F 3 186 ? 93.569 22.854 -26.928 1.00 92.67 ? 163 LYS M C 1 ATOM 9439 O O . LYS F 3 186 ? 93.178 22.261 -27.930 1.00 93.32 ? 163 LYS M O 1 ATOM 9440 C CB . LYS F 3 186 ? 91.995 23.642 -25.161 1.00 93.90 ? 163 LYS M CB 1 ATOM 9441 C CG . LYS F 3 186 ? 91.163 22.356 -25.300 1.00 93.96 ? 163 LYS M CG 1 ATOM 9442 C CD . LYS F 3 186 ? 90.055 22.466 -26.354 1.00 94.76 ? 163 LYS M CD 1 ATOM 9443 C CE . LYS F 3 186 ? 89.085 23.631 -26.095 1.00 94.56 ? 163 LYS M CE 1 ATOM 9444 N NZ . LYS F 3 186 ? 88.310 23.513 -24.827 1.00 92.53 ? 163 LYS M NZ 1 ATOM 9445 N N . PRO F 3 187 ? 94.675 22.484 -26.270 1.00 92.03 ? 164 PRO M N 1 ATOM 9446 C CA . PRO F 3 187 ? 95.456 21.329 -26.720 1.00 91.89 ? 164 PRO M CA 1 ATOM 9447 C C . PRO F 3 187 ? 94.544 20.106 -26.809 1.00 91.72 ? 164 PRO M C 1 ATOM 9448 O O . PRO F 3 187 ? 93.409 20.153 -26.341 1.00 92.12 ? 164 PRO M O 1 ATOM 9449 C CB . PRO F 3 187 ? 96.517 21.192 -25.631 1.00 92.38 ? 164 PRO M CB 1 ATOM 9450 C CG . PRO F 3 187 ? 96.721 22.615 -25.180 1.00 91.61 ? 164 PRO M CG 1 ATOM 9451 C CD . PRO F 3 187 ? 95.308 23.134 -25.108 1.00 91.79 ? 164 PRO M CD 1 ATOM 9452 N N . SER F 3 188 ? 95.033 19.021 -27.406 1.00 91.61 ? 165 SER M N 1 ATOM 9453 C CA . SER F 3 188 ? 94.242 17.803 -27.546 1.00 91.94 ? 165 SER M CA 1 ATOM 9454 C C . SER F 3 188 ? 95.121 16.636 -27.931 1.00 92.20 ? 165 SER M C 1 ATOM 9455 O O . SER F 3 188 ? 95.852 16.705 -28.910 1.00 92.40 ? 165 SER M O 1 ATOM 9456 C CB . SER F 3 188 ? 93.166 17.984 -28.612 1.00 92.67 ? 165 SER M CB 1 ATOM 9457 O OG . SER F 3 188 ? 92.235 18.986 -28.236 1.00 95.33 ? 165 SER M OG 1 ATOM 9458 N N . LYS F 3 189 ? 95.030 15.557 -27.168 1.00 93.50 ? 166 LYS M N 1 ATOM 9459 C CA . LYS F 3 189 ? 95.833 14.366 -27.414 1.00 95.36 ? 166 LYS M CA 1 ATOM 9460 C C . LYS F 3 189 ? 95.488 13.618 -28.697 1.00 96.41 ? 166 LYS M C 1 ATOM 9461 O O . LYS F 3 189 ? 94.362 13.666 -29.180 1.00 95.75 ? 166 LYS M O 1 ATOM 9462 C CB . LYS F 3 189 ? 95.719 13.409 -26.220 1.00 96.13 ? 166 LYS M CB 1 ATOM 9463 C CG . LYS F 3 189 ? 96.438 12.070 -26.399 1.00 96.63 ? 166 LYS M CG 1 ATOM 9464 C CD . LYS F 3 189 ? 96.379 11.216 -25.135 1.00 95.69 ? 166 LYS M CD 1 ATOM 9465 C CE . LYS F 3 189 ? 97.071 11.908 -23.970 1.00 95.69 ? 166 LYS M CE 1 ATOM 9466 N NZ . LYS F 3 189 ? 98.497 12.224 -24.272 1.00 95.01 ? 166 LYS M NZ 1 ATOM 9467 N N . GLN F 3 190 ? 96.489 12.929 -29.236 1.00 99.01 ? 167 GLN M N 1 ATOM 9468 C CA . GLN F 3 190 ? 96.357 12.129 -30.451 1.00 101.28 ? 167 GLN M CA 1 ATOM 9469 C C . GLN F 3 190 ? 96.696 10.680 -30.087 1.00 101.74 ? 167 GLN M C 1 ATOM 9470 O O . GLN F 3 190 ? 96.793 10.327 -28.908 1.00 101.06 ? 167 GLN M O 1 ATOM 9471 C CB . GLN F 3 190 ? 97.354 12.596 -31.527 1.00 102.76 ? 167 GLN M CB 1 ATOM 9472 C CG . GLN F 3 190 ? 97.151 14.000 -32.097 1.00 104.44 ? 167 GLN M CG 1 ATOM 9473 C CD . GLN F 3 190 ? 98.162 14.335 -33.200 1.00 105.75 ? 167 GLN M CD 1 ATOM 9474 O OE1 . GLN F 3 190 ? 99.366 14.435 -32.950 1.00 105.34 ? 167 GLN M OE1 1 ATOM 9475 N NE2 . GLN F 3 190 ? 97.670 14.498 -34.428 1.00 105.97 ? 167 GLN M NE2 1 ATOM 9476 N N . SER F 3 191 ? 96.871 9.846 -31.109 1.00 102.69 ? 168 SER M N 1 ATOM 9477 C CA . SER F 3 191 ? 97.253 8.457 -30.895 1.00 103.46 ? 168 SER M CA 1 ATOM 9478 C C . SER F 3 191 ? 98.712 8.566 -30.479 1.00 103.51 ? 168 SER M C 1 ATOM 9479 O O . SER F 3 191 ? 99.205 7.805 -29.649 1.00 103.49 ? 168 SER M O 1 ATOM 9480 C CB . SER F 3 191 ? 97.146 7.653 -32.196 1.00 103.71 ? 168 SER M CB 1 ATOM 9481 O OG . SER F 3 191 ? 95.809 7.597 -32.665 1.00 104.28 ? 168 SER M OG 1 ATOM 9482 N N . ASN F 3 192 ? 99.389 9.545 -31.069 1.00 103.40 ? 169 ASN M N 1 ATOM 9483 C CA . ASN F 3 192 ? 100.786 9.811 -30.779 1.00 103.55 ? 169 ASN M CA 1 ATOM 9484 C C . ASN F 3 192 ? 100.952 10.124 -29.299 1.00 103.15 ? 169 ASN M C 1 ATOM 9485 O O . ASN F 3 192 ? 102.072 10.190 -28.795 1.00 103.77 ? 169 ASN M O 1 ATOM 9486 C CB . ASN F 3 192 ? 101.275 11.021 -31.582 1.00 104.44 ? 169 ASN M CB 1 ATOM 9487 C CG . ASN F 3 192 ? 101.249 10.789 -33.078 1.00 106.13 ? 169 ASN M CG 1 ATOM 9488 O OD1 . ASN F 3 192 ? 101.619 11.672 -33.859 1.00 106.67 ? 169 ASN M OD1 1 ATOM 9489 N ND2 . ASN F 3 192 ? 100.814 9.601 -33.489 1.00 106.27 ? 169 ASN M ND2 1 ATOM 9490 N N . ASN F 3 193 ? 99.837 10.319 -28.602 1.00 102.06 ? 170 ASN M N 1 ATOM 9491 C CA . ASN F 3 193 ? 99.886 10.679 -27.191 1.00 100.30 ? 170 ASN M CA 1 ATOM 9492 C C . ASN F 3 193 ? 100.557 12.037 -27.175 1.00 98.72 ? 170 ASN M C 1 ATOM 9493 O O . ASN F 3 193 ? 100.792 12.628 -26.125 1.00 98.36 ? 170 ASN M O 1 ATOM 9494 C CB . ASN F 3 193 ? 100.694 9.664 -26.398 1.00 101.03 ? 170 ASN M CB 1 ATOM 9495 C CG . ASN F 3 193 ? 100.085 8.287 -26.458 1.00 102.94 ? 170 ASN M CG 1 ATOM 9496 O OD1 . ASN F 3 193 ? 98.926 8.101 -26.094 1.00 104.63 ? 170 ASN M OD1 1 ATOM 9497 N ND2 . ASN F 3 193 ? 100.856 7.313 -26.925 1.00 104.18 ? 170 ASN M ND2 1 ATOM 9498 N N . LYS F 3 194 ? 100.875 12.504 -28.377 1.00 97.07 ? 171 LYS M N 1 ATOM 9499 C CA . LYS F 3 194 ? 101.472 13.807 -28.590 1.00 95.71 ? 171 LYS M CA 1 ATOM 9500 C C . LYS F 3 194 ? 100.211 14.619 -28.784 1.00 93.53 ? 171 LYS M C 1 ATOM 9501 O O . LYS F 3 194 ? 99.230 14.113 -29.322 1.00 93.45 ? 171 LYS M O 1 ATOM 9502 C CB . LYS F 3 194 ? 102.295 13.825 -29.881 1.00 97.37 ? 171 LYS M CB 1 ATOM 9503 C CG . LYS F 3 194 ? 103.375 12.752 -29.972 1.00 99.89 ? 171 LYS M CG 1 ATOM 9504 C CD . LYS F 3 194 ? 104.546 13.008 -29.025 1.00 101.32 ? 171 LYS M CD 1 ATOM 9505 C CE . LYS F 3 194 ? 105.547 11.856 -29.067 1.00 100.99 ? 171 LYS M CE 1 ATOM 9506 N NZ . LYS F 3 194 ? 105.989 11.554 -30.458 1.00 101.01 ? 171 LYS M NZ 1 ATOM 9507 N N . TYR F 3 195 ? 100.212 15.867 -28.357 1.00 90.77 ? 172 TYR M N 1 ATOM 9508 C CA . TYR F 3 195 ? 99.011 16.653 -28.505 1.00 88.91 ? 172 TYR M CA 1 ATOM 9509 C C . TYR F 3 195 ? 98.957 17.412 -29.817 1.00 86.49 ? 172 TYR M C 1 ATOM 9510 O O . TYR F 3 195 ? 99.878 17.340 -30.620 1.00 85.90 ? 172 TYR M O 1 ATOM 9511 C CB . TYR F 3 195 ? 98.876 17.596 -27.313 1.00 91.15 ? 172 TYR M CB 1 ATOM 9512 C CG . TYR F 3 195 ? 98.806 16.843 -26.003 1.00 93.69 ? 172 TYR M CG 1 ATOM 9513 C CD1 . TYR F 3 195 ? 99.949 16.271 -25.446 1.00 94.54 ? 172 TYR M CD1 1 ATOM 9514 C CD2 . TYR F 3 195 ? 97.588 16.657 -25.344 1.00 94.56 ? 172 TYR M CD2 1 ATOM 9515 C CE1 . TYR F 3 195 ? 99.885 15.533 -24.265 1.00 95.63 ? 172 TYR M CE1 1 ATOM 9516 C CE2 . TYR F 3 195 ? 97.513 15.916 -24.160 1.00 95.42 ? 172 TYR M CE2 1 ATOM 9517 C CZ . TYR F 3 195 ? 98.666 15.359 -23.628 1.00 95.75 ? 172 TYR M CZ 1 ATOM 9518 O OH . TYR F 3 195 ? 98.609 14.637 -22.458 1.00 96.32 ? 172 TYR M OH 1 ATOM 9519 N N . ALA F 3 196 ? 97.853 18.116 -30.037 1.00 84.04 ? 173 ALA M N 1 ATOM 9520 C CA . ALA F 3 196 ? 97.655 18.905 -31.245 1.00 81.56 ? 173 ALA M CA 1 ATOM 9521 C C . ALA F 3 196 ? 96.529 19.903 -31.007 1.00 79.97 ? 173 ALA M C 1 ATOM 9522 O O . ALA F 3 196 ? 95.546 19.594 -30.339 1.00 79.29 ? 173 ALA M O 1 ATOM 9523 C CB . ALA F 3 196 ? 97.315 18.000 -32.409 1.00 81.13 ? 173 ALA M CB 1 ATOM 9524 N N . ALA F 3 197 ? 96.686 21.104 -31.544 1.00 78.39 ? 174 ALA M N 1 ATOM 9525 C CA . ALA F 3 197 ? 95.688 22.144 -31.385 1.00 77.84 ? 174 ALA M CA 1 ATOM 9526 C C . ALA F 3 197 ? 95.765 23.049 -32.595 1.00 79.08 ? 174 ALA M C 1 ATOM 9527 O O . ALA F 3 197 ? 96.339 22.675 -33.616 1.00 79.25 ? 174 ALA M O 1 ATOM 9528 C CB . ALA F 3 197 ? 95.959 22.935 -30.127 1.00 75.43 ? 174 ALA M CB 1 ATOM 9529 N N . SER F 3 198 ? 95.183 24.236 -32.489 1.00 81.02 ? 175 SER M N 1 ATOM 9530 C CA . SER F 3 198 ? 95.214 25.192 -33.591 1.00 83.35 ? 175 SER M CA 1 ATOM 9531 C C . SER F 3 198 ? 94.699 26.546 -33.126 1.00 83.71 ? 175 SER M C 1 ATOM 9532 O O . SER F 3 198 ? 94.277 26.696 -31.983 1.00 83.63 ? 175 SER M O 1 ATOM 9533 C CB . SER F 3 198 ? 94.365 24.693 -34.764 1.00 83.79 ? 175 SER M CB 1 ATOM 9534 O OG . SER F 3 198 ? 92.986 24.740 -34.442 1.00 86.61 ? 175 SER M OG 1 ATOM 9535 N N . SER F 3 199 ? 94.740 27.530 -34.016 1.00 84.84 ? 176 SER M N 1 ATOM 9536 C CA . SER F 3 199 ? 94.273 28.870 -33.691 1.00 85.89 ? 176 SER M CA 1 ATOM 9537 C C . SER F 3 199 ? 93.859 29.618 -34.947 1.00 86.57 ? 176 SER M C 1 ATOM 9538 O O . SER F 3 199 ? 94.495 29.493 -35.993 1.00 86.35 ? 176 SER M O 1 ATOM 9539 C CB . SER F 3 199 ? 95.366 29.655 -32.970 1.00 85.83 ? 176 SER M CB 1 ATOM 9540 O OG . SER F 3 199 ? 94.940 30.979 -32.697 1.00 85.64 ? 176 SER M OG 1 ATOM 9541 N N . TYR F 3 200 ? 92.789 30.398 -34.830 1.00 87.42 ? 177 TYR M N 1 ATOM 9542 C CA . TYR F 3 200 ? 92.270 31.173 -35.947 1.00 87.76 ? 177 TYR M CA 1 ATOM 9543 C C . TYR F 3 200 ? 92.349 32.656 -35.625 1.00 88.67 ? 177 TYR M C 1 ATOM 9544 O O . TYR F 3 200 ? 92.532 33.040 -34.475 1.00 88.73 ? 177 TYR M O 1 ATOM 9545 C CB . TYR F 3 200 ? 90.806 30.808 -36.216 1.00 86.43 ? 177 TYR M CB 1 ATOM 9546 C CG . TYR F 3 200 ? 90.548 29.343 -36.501 1.00 85.26 ? 177 TYR M CG 1 ATOM 9547 C CD1 . TYR F 3 200 ? 90.883 28.355 -35.573 1.00 85.03 ? 177 TYR M CD1 1 ATOM 9548 C CD2 . TYR F 3 200 ? 89.937 28.947 -37.686 1.00 84.11 ? 177 TYR M CD2 1 ATOM 9549 C CE1 . TYR F 3 200 ? 90.613 27.011 -35.819 1.00 83.55 ? 177 TYR M CE1 1 ATOM 9550 C CE2 . TYR F 3 200 ? 89.660 27.609 -37.942 1.00 83.16 ? 177 TYR M CE2 1 ATOM 9551 C CZ . TYR F 3 200 ? 89.999 26.646 -37.007 1.00 83.08 ? 177 TYR M CZ 1 ATOM 9552 O OH . TYR F 3 200 ? 89.708 25.323 -37.258 1.00 82.20 ? 177 TYR M OH 1 ATOM 9553 N N . LEU F 3 201 ? 92.216 33.484 -36.652 1.00 90.50 ? 178 LEU M N 1 ATOM 9554 C CA . LEU F 3 201 ? 92.229 34.931 -36.489 1.00 92.94 ? 178 LEU M CA 1 ATOM 9555 C C . LEU F 3 201 ? 91.188 35.487 -37.449 1.00 96.17 ? 178 LEU M C 1 ATOM 9556 O O . LEU F 3 201 ? 91.244 35.223 -38.650 1.00 96.36 ? 178 LEU M O 1 ATOM 9557 C CB . LEU F 3 201 ? 93.609 35.504 -36.811 1.00 90.66 ? 178 LEU M CB 1 ATOM 9558 C CG . LEU F 3 201 ? 93.713 37.031 -36.804 1.00 88.96 ? 178 LEU M CG 1 ATOM 9559 C CD1 . LEU F 3 201 ? 93.245 37.583 -35.477 1.00 88.40 ? 178 LEU M CD1 1 ATOM 9560 C CD2 . LEU F 3 201 ? 95.144 37.443 -37.076 1.00 89.27 ? 178 LEU M CD2 1 ATOM 9561 N N . SER F 3 202 ? 90.232 36.241 -36.916 1.00 99.94 ? 179 SER M N 1 ATOM 9562 C CA . SER F 3 202 ? 89.167 36.814 -37.728 1.00 104.42 ? 179 SER M CA 1 ATOM 9563 C C . SER F 3 202 ? 89.695 37.698 -38.851 1.00 107.51 ? 179 SER M C 1 ATOM 9564 O O . SER F 3 202 ? 90.215 37.199 -39.845 1.00 108.31 ? 179 SER M O 1 ATOM 9565 C CB . SER F 3 202 ? 88.208 37.611 -36.843 1.00 105.07 ? 179 SER M CB 1 ATOM 9566 O OG . SER F 3 202 ? 87.540 36.760 -35.924 1.00 106.59 ? 179 SER M OG 1 ATOM 9567 N N . LEU F 3 203 ? 89.551 39.010 -38.698 1.00 111.39 ? 180 LEU M N 1 ATOM 9568 C CA . LEU F 3 203 ? 90.016 39.964 -39.704 1.00 114.82 ? 180 LEU M CA 1 ATOM 9569 C C . LEU F 3 203 ? 89.259 39.820 -41.022 1.00 117.18 ? 180 LEU M C 1 ATOM 9570 O O . LEU F 3 203 ? 89.078 38.711 -41.522 1.00 117.28 ? 180 LEU M O 1 ATOM 9571 C CB . LEU F 3 203 ? 91.512 39.771 -39.969 1.00 114.63 ? 180 LEU M CB 1 ATOM 9572 C CG . LEU F 3 203 ? 92.447 39.564 -38.774 1.00 115.11 ? 180 LEU M CG 1 ATOM 9573 C CD1 . LEU F 3 203 ? 93.864 39.496 -39.304 1.00 115.09 ? 180 LEU M CD1 1 ATOM 9574 C CD2 . LEU F 3 203 ? 92.306 40.687 -37.749 1.00 115.24 ? 180 LEU M CD2 1 ATOM 9575 N N . THR F 3 204 ? 88.820 40.944 -41.582 1.00 120.23 ? 181 THR M N 1 ATOM 9576 C CA . THR F 3 204 ? 88.094 40.938 -42.851 1.00 123.48 ? 181 THR M CA 1 ATOM 9577 C C . THR F 3 204 ? 89.097 40.943 -44.009 1.00 125.99 ? 181 THR M C 1 ATOM 9578 O O . THR F 3 204 ? 90.307 40.974 -43.784 1.00 126.31 ? 181 THR M O 1 ATOM 9579 C CB . THR F 3 204 ? 87.161 42.173 -42.968 1.00 123.23 ? 181 THR M CB 1 ATOM 9580 O OG1 . THR F 3 204 ? 87.923 43.375 -42.801 1.00 123.20 ? 181 THR M OG1 1 ATOM 9581 C CG2 . THR F 3 204 ? 86.067 42.116 -41.916 1.00 123.56 ? 181 THR M CG2 1 ATOM 9582 N N . PRO F 3 205 ? 88.613 40.893 -45.264 1.00 128.35 ? 182 PRO M N 1 ATOM 9583 C CA . PRO F 3 205 ? 89.556 40.900 -46.386 1.00 130.26 ? 182 PRO M CA 1 ATOM 9584 C C . PRO F 3 205 ? 90.235 42.259 -46.542 1.00 132.13 ? 182 PRO M C 1 ATOM 9585 O O . PRO F 3 205 ? 91.421 42.340 -46.870 1.00 132.37 ? 182 PRO M O 1 ATOM 9586 C CB . PRO F 3 205 ? 88.669 40.549 -47.580 1.00 129.71 ? 182 PRO M CB 1 ATOM 9587 C CG . PRO F 3 205 ? 87.363 41.167 -47.207 1.00 128.86 ? 182 PRO M CG 1 ATOM 9588 C CD . PRO F 3 205 ? 87.228 40.767 -45.753 1.00 128.81 ? 182 PRO M CD 1 ATOM 9589 N N . GLU F 3 206 ? 89.472 43.321 -46.293 1.00 134.12 ? 183 GLU M N 1 ATOM 9590 C CA . GLU F 3 206 ? 89.977 44.685 -46.400 1.00 136.27 ? 183 GLU M CA 1 ATOM 9591 C C . GLU F 3 206 ? 91.114 44.931 -45.413 1.00 137.41 ? 183 GLU M C 1 ATOM 9592 O O . GLU F 3 206 ? 91.752 45.987 -45.439 1.00 137.99 ? 183 GLU M O 1 ATOM 9593 C CB . GLU F 3 206 ? 88.842 45.682 -46.150 1.00 136.94 ? 183 GLU M CB 1 ATOM 9594 C CG . GLU F 3 206 ? 87.660 45.518 -47.102 1.00 138.83 ? 183 GLU M CG 1 ATOM 9595 C CD . GLU F 3 206 ? 86.529 46.499 -46.828 1.00 139.76 ? 183 GLU M CD 1 ATOM 9596 O OE1 . GLU F 3 206 ? 85.999 46.501 -45.694 1.00 140.10 ? 183 GLU M OE1 1 ATOM 9597 O OE2 . GLU F 3 206 ? 86.168 47.265 -47.749 1.00 139.95 ? 183 GLU M OE2 1 ATOM 9598 N N . GLN F 3 207 ? 91.367 43.950 -44.550 1.00 138.23 ? 184 GLN M N 1 ATOM 9599 C CA . GLN F 3 207 ? 92.430 44.050 -43.552 1.00 138.89 ? 184 GLN M CA 1 ATOM 9600 C C . GLN F 3 207 ? 93.655 43.253 -43.986 1.00 138.92 ? 184 GLN M C 1 ATOM 9601 O O . GLN F 3 207 ? 94.787 43.622 -43.674 1.00 138.74 ? 184 GLN M O 1 ATOM 9602 C CB . GLN F 3 207 ? 91.953 43.510 -42.199 1.00 139.55 ? 184 GLN M CB 1 ATOM 9603 C CG . GLN F 3 207 ? 90.606 44.035 -41.727 1.00 140.47 ? 184 GLN M CG 1 ATOM 9604 C CD . GLN F 3 207 ? 90.205 43.467 -40.373 1.00 140.86 ? 184 GLN M CD 1 ATOM 9605 O OE1 . GLN F 3 207 ? 89.065 43.621 -39.933 1.00 141.53 ? 184 GLN M OE1 1 ATOM 9606 N NE2 . GLN F 3 207 ? 91.147 42.812 -39.704 1.00 140.88 ? 184 GLN M NE2 1 ATOM 9607 N N . TRP F 3 208 ? 93.418 42.153 -44.699 1.00 139.18 ? 185 TRP M N 1 ATOM 9608 C CA . TRP F 3 208 ? 94.495 41.283 -45.165 1.00 139.21 ? 185 TRP M CA 1 ATOM 9609 C C . TRP F 3 208 ? 95.197 41.814 -46.406 1.00 139.55 ? 185 TRP M C 1 ATOM 9610 O O . TRP F 3 208 ? 96.413 42.021 -46.403 1.00 140.06 ? 185 TRP M O 1 ATOM 9611 C CB . TRP F 3 208 ? 93.960 39.878 -45.464 1.00 138.59 ? 185 TRP M CB 1 ATOM 9612 C CG . TRP F 3 208 ? 95.023 38.929 -45.946 1.00 137.80 ? 185 TRP M CG 1 ATOM 9613 C CD1 . TRP F 3 208 ? 96.134 38.522 -45.259 1.00 137.42 ? 185 TRP M CD1 1 ATOM 9614 C CD2 . TRP F 3 208 ? 95.087 38.287 -47.226 1.00 137.47 ? 185 TRP M CD2 1 ATOM 9615 N NE1 . TRP F 3 208 ? 96.884 37.668 -46.031 1.00 136.93 ? 185 TRP M NE1 1 ATOM 9616 C CE2 . TRP F 3 208 ? 96.265 37.506 -47.243 1.00 137.21 ? 185 TRP M CE2 1 ATOM 9617 C CE3 . TRP F 3 208 ? 94.264 38.295 -48.359 1.00 137.46 ? 185 TRP M CE3 1 ATOM 9618 C CZ2 . TRP F 3 208 ? 96.642 36.740 -48.353 1.00 137.10 ? 185 TRP M CZ2 1 ATOM 9619 C CZ3 . TRP F 3 208 ? 94.640 37.532 -49.465 1.00 137.62 ? 185 TRP M CZ3 1 ATOM 9620 C CH2 . TRP F 3 208 ? 95.819 36.765 -49.450 1.00 137.25 ? 185 TRP M CH2 1 ATOM 9621 N N . LYS F 3 209 ? 94.429 42.024 -47.470 1.00 139.24 ? 186 LYS M N 1 ATOM 9622 C CA . LYS F 3 209 ? 94.982 42.518 -48.723 1.00 138.91 ? 186 LYS M CA 1 ATOM 9623 C C . LYS F 3 209 ? 95.702 43.858 -48.558 1.00 138.87 ? 186 LYS M C 1 ATOM 9624 O O . LYS F 3 209 ? 96.329 44.357 -49.494 1.00 138.73 ? 186 LYS M O 1 ATOM 9625 C CB . LYS F 3 209 ? 93.865 42.636 -49.763 1.00 138.40 ? 186 LYS M CB 1 ATOM 9626 C CG . LYS F 3 209 ? 93.202 41.303 -50.088 1.00 138.01 ? 186 LYS M CG 1 ATOM 9627 C CD . LYS F 3 209 ? 92.124 41.445 -51.151 1.00 137.19 ? 186 LYS M CD 1 ATOM 9628 C CE . LYS F 3 209 ? 91.541 40.091 -51.518 1.00 136.55 ? 186 LYS M CE 1 ATOM 9629 N NZ . LYS F 3 209 ? 90.473 40.211 -52.542 1.00 135.93 ? 186 LYS M NZ 1 ATOM 9630 N N . SER F 3 210 ? 95.622 44.426 -47.358 1.00 138.71 ? 187 SER M N 1 ATOM 9631 C CA . SER F 3 210 ? 96.258 45.706 -47.064 1.00 138.00 ? 187 SER M CA 1 ATOM 9632 C C . SER F 3 210 ? 97.602 45.554 -46.339 1.00 137.51 ? 187 SER M C 1 ATOM 9633 O O . SER F 3 210 ? 98.655 45.543 -46.975 1.00 137.37 ? 187 SER M O 1 ATOM 9634 C CB . SER F 3 210 ? 95.310 46.579 -46.229 1.00 138.00 ? 187 SER M CB 1 ATOM 9635 O OG . SER F 3 210 ? 94.089 46.819 -46.912 1.00 137.14 ? 187 SER M OG 1 ATOM 9636 N N . HIS F 3 211 ? 97.550 45.435 -45.012 1.00 136.99 ? 188 HIS M N 1 ATOM 9637 C CA . HIS F 3 211 ? 98.736 45.305 -44.154 1.00 136.37 ? 188 HIS M CA 1 ATOM 9638 C C . HIS F 3 211 ? 99.887 44.452 -44.702 1.00 135.97 ? 188 HIS M C 1 ATOM 9639 O O . HIS F 3 211 ? 99.734 43.745 -45.699 1.00 136.24 ? 188 HIS M O 1 ATOM 9640 C CB . HIS F 3 211 ? 98.316 44.778 -42.775 1.00 136.44 ? 188 HIS M CB 1 ATOM 9641 C CG . HIS F 3 211 ? 97.480 45.741 -41.987 1.00 136.48 ? 188 HIS M CG 1 ATOM 9642 N ND1 . HIS F 3 211 ? 96.323 46.304 -42.483 1.00 136.61 ? 188 HIS M ND1 1 ATOM 9643 C CD2 . HIS F 3 211 ? 97.635 46.242 -40.739 1.00 136.36 ? 188 HIS M CD2 1 ATOM 9644 C CE1 . HIS F 3 211 ? 95.804 47.112 -41.575 1.00 136.22 ? 188 HIS M CE1 1 ATOM 9645 N NE2 . HIS F 3 211 ? 96.580 47.093 -40.507 1.00 135.97 ? 188 HIS M NE2 1 ATOM 9646 N N . ARG F 3 212 ? 101.041 44.522 -44.036 1.00 135.22 ? 189 ARG M N 1 ATOM 9647 C CA . ARG F 3 212 ? 102.227 43.772 -44.457 1.00 134.41 ? 189 ARG M CA 1 ATOM 9648 C C . ARG F 3 212 ? 102.459 42.465 -43.698 1.00 133.41 ? 189 ARG M C 1 ATOM 9649 O O . ARG F 3 212 ? 103.320 42.389 -42.817 1.00 133.44 ? 189 ARG M O 1 ATOM 9650 C CB . ARG F 3 212 ? 103.488 44.641 -44.335 1.00 135.20 ? 189 ARG M CB 1 ATOM 9651 C CG . ARG F 3 212 ? 104.765 43.922 -44.772 1.00 135.75 ? 189 ARG M CG 1 ATOM 9652 C CD . ARG F 3 212 ? 106.040 44.671 -44.390 1.00 136.83 ? 189 ARG M CD 1 ATOM 9653 N NE . ARG F 3 212 ? 106.223 45.915 -45.134 1.00 137.82 ? 189 ARG M NE 1 ATOM 9654 C CZ . ARG F 3 212 ? 107.345 46.633 -45.127 1.00 138.06 ? 189 ARG M CZ 1 ATOM 9655 N NH1 . ARG F 3 212 ? 108.390 46.231 -44.416 1.00 138.32 ? 189 ARG M NH1 1 ATOM 9656 N NH2 . ARG F 3 212 ? 107.423 47.755 -45.830 1.00 138.01 ? 189 ARG M NH2 1 ATOM 9657 N N . SER F 3 213 ? 101.686 41.441 -44.045 1.00 131.92 ? 190 SER M N 1 ATOM 9658 C CA . SER F 3 213 ? 101.814 40.118 -43.438 1.00 129.90 ? 190 SER M CA 1 ATOM 9659 C C . SER F 3 213 ? 101.516 40.031 -41.940 1.00 127.96 ? 190 SER M C 1 ATOM 9660 O O . SER F 3 213 ? 101.898 40.906 -41.164 1.00 127.59 ? 190 SER M O 1 ATOM 9661 C CB . SER F 3 213 ? 103.225 39.580 -43.695 1.00 130.39 ? 190 SER M CB 1 ATOM 9662 O OG . SER F 3 213 ? 103.582 39.730 -45.059 1.00 130.47 ? 190 SER M OG 1 ATOM 9663 N N . TYR F 3 214 ? 100.832 38.958 -41.549 1.00 125.77 ? 191 TYR M N 1 ATOM 9664 C CA . TYR F 3 214 ? 100.500 38.710 -40.149 1.00 123.88 ? 191 TYR M CA 1 ATOM 9665 C C . TYR F 3 214 ? 101.354 37.537 -39.667 1.00 122.98 ? 191 TYR M C 1 ATOM 9666 O O . TYR F 3 214 ? 101.983 36.856 -40.478 1.00 122.78 ? 191 TYR M O 1 ATOM 9667 C CB . TYR F 3 214 ? 99.015 38.377 -39.993 1.00 122.81 ? 191 TYR M CB 1 ATOM 9668 C CG . TYR F 3 214 ? 98.090 39.523 -40.328 1.00 121.63 ? 191 TYR M CG 1 ATOM 9669 C CD1 . TYR F 3 214 ? 97.914 39.939 -41.645 1.00 121.31 ? 191 TYR M CD1 1 ATOM 9670 C CD2 . TYR F 3 214 ? 97.391 40.195 -39.326 1.00 121.09 ? 191 TYR M CD2 1 ATOM 9671 C CE1 . TYR F 3 214 ? 97.062 40.995 -41.959 1.00 121.04 ? 191 TYR M CE1 1 ATOM 9672 C CE2 . TYR F 3 214 ? 96.539 41.253 -39.627 1.00 120.60 ? 191 TYR M CE2 1 ATOM 9673 C CZ . TYR F 3 214 ? 96.377 41.648 -40.945 1.00 120.54 ? 191 TYR M CZ 1 ATOM 9674 O OH . TYR F 3 214 ? 95.529 42.686 -41.255 1.00 119.50 ? 191 TYR M OH 1 ATOM 9675 N N . SER F 3 215 ? 101.372 37.288 -38.359 1.00 121.73 ? 192 SER M N 1 ATOM 9676 C CA . SER F 3 215 ? 102.190 36.202 -37.825 1.00 120.52 ? 192 SER M CA 1 ATOM 9677 C C . SER F 3 215 ? 101.556 35.395 -36.688 1.00 119.45 ? 192 SER M C 1 ATOM 9678 O O . SER F 3 215 ? 100.893 35.947 -35.811 1.00 118.88 ? 192 SER M O 1 ATOM 9679 C CB . SER F 3 215 ? 103.530 36.769 -37.344 1.00 121.22 ? 192 SER M CB 1 ATOM 9680 O OG . SER F 3 215 ? 104.105 37.631 -38.313 1.00 120.88 ? 192 SER M OG 1 ATOM 9681 N N . CYS F 3 216 ? 101.780 34.082 -36.713 1.00 118.44 ? 193 CYS M N 1 ATOM 9682 C CA . CYS F 3 216 ? 101.272 33.178 -35.682 1.00 117.56 ? 193 CYS M CA 1 ATOM 9683 C C . CYS F 3 216 ? 102.448 32.651 -34.858 1.00 118.37 ? 193 CYS M C 1 ATOM 9684 O O . CYS F 3 216 ? 103.201 31.784 -35.304 1.00 118.02 ? 193 CYS M O 1 ATOM 9685 C CB . CYS F 3 216 ? 100.510 31.998 -36.305 1.00 115.03 ? 193 CYS M CB 1 ATOM 9686 S SG . CYS F 3 216 ? 100.010 30.726 -35.092 1.00 111.79 ? 193 CYS M SG 1 ATOM 9687 N N . GLN F 3 217 ? 102.596 33.183 -33.651 1.00 119.54 ? 194 GLN M N 1 ATOM 9688 C CA . GLN F 3 217 ? 103.681 32.783 -32.772 1.00 121.04 ? 194 GLN M CA 1 ATOM 9689 C C . GLN F 3 217 ? 103.228 31.824 -31.684 1.00 122.20 ? 194 GLN M C 1 ATOM 9690 O O . GLN F 3 217 ? 102.475 32.195 -30.786 1.00 122.36 ? 194 GLN M O 1 ATOM 9691 C CB . GLN F 3 217 ? 104.310 34.024 -32.140 1.00 121.12 ? 194 GLN M CB 1 ATOM 9692 C CG . GLN F 3 217 ? 104.992 34.935 -33.147 1.00 121.92 ? 194 GLN M CG 1 ATOM 9693 C CD . GLN F 3 217 ? 105.310 36.303 -32.584 1.00 121.93 ? 194 GLN M CD 1 ATOM 9694 O OE1 . GLN F 3 217 ? 104.412 37.105 -32.331 1.00 121.55 ? 194 GLN M OE1 1 ATOM 9695 N NE2 . GLN F 3 217 ? 106.595 36.576 -32.377 1.00 122.30 ? 194 GLN M NE2 1 ATOM 9696 N N . VAL F 3 218 ? 103.691 30.583 -31.780 1.00 123.67 ? 195 VAL M N 1 ATOM 9697 C CA . VAL F 3 218 ? 103.364 29.555 -30.799 1.00 125.28 ? 195 VAL M CA 1 ATOM 9698 C C . VAL F 3 218 ? 104.432 29.607 -29.706 1.00 126.55 ? 195 VAL M C 1 ATOM 9699 O O . VAL F 3 218 ? 105.447 30.285 -29.866 1.00 127.14 ? 195 VAL M O 1 ATOM 9700 C CB . VAL F 3 218 ? 103.358 28.153 -31.452 1.00 124.85 ? 195 VAL M CB 1 ATOM 9701 C CG1 . VAL F 3 218 ? 103.012 27.090 -30.424 1.00 124.43 ? 195 VAL M CG1 1 ATOM 9702 C CG2 . VAL F 3 218 ? 102.360 28.126 -32.598 1.00 124.85 ? 195 VAL M CG2 1 ATOM 9703 N N . THR F 3 219 ? 104.202 28.909 -28.596 1.00 127.98 ? 196 THR M N 1 ATOM 9704 C CA . THR F 3 219 ? 105.164 28.891 -27.495 1.00 129.28 ? 196 THR M CA 1 ATOM 9705 C C . THR F 3 219 ? 105.077 27.594 -26.694 1.00 129.90 ? 196 THR M C 1 ATOM 9706 O O . THR F 3 219 ? 104.253 27.474 -25.790 1.00 130.15 ? 196 THR M O 1 ATOM 9707 C CB . THR F 3 219 ? 104.935 30.077 -26.524 1.00 129.40 ? 196 THR M CB 1 ATOM 9708 O OG1 . THR F 3 219 ? 104.999 31.313 -27.248 1.00 129.33 ? 196 THR M OG1 1 ATOM 9709 C CG2 . THR F 3 219 ? 105.998 30.085 -25.432 1.00 129.12 ? 196 THR M CG2 1 ATOM 9710 N N . HIS F 3 220 ? 105.927 26.627 -27.025 1.00 130.71 ? 197 HIS M N 1 ATOM 9711 C CA . HIS F 3 220 ? 105.934 25.352 -26.319 1.00 131.76 ? 197 HIS M CA 1 ATOM 9712 C C . HIS F 3 220 ? 107.078 25.336 -25.312 1.00 133.18 ? 197 HIS M C 1 ATOM 9713 O O . HIS F 3 220 ? 108.211 24.995 -25.653 1.00 133.43 ? 197 HIS M O 1 ATOM 9714 C CB . HIS F 3 220 ? 106.107 24.190 -27.298 1.00 131.15 ? 197 HIS M CB 1 ATOM 9715 C CG . HIS F 3 220 ? 105.769 22.856 -26.710 1.00 130.70 ? 197 HIS M CG 1 ATOM 9716 N ND1 . HIS F 3 220 ? 106.179 22.473 -25.451 1.00 130.71 ? 197 HIS M ND1 1 ATOM 9717 C CD2 . HIS F 3 220 ? 105.054 21.817 -27.202 1.00 130.70 ? 197 HIS M CD2 1 ATOM 9718 C CE1 . HIS F 3 220 ? 105.730 21.259 -25.193 1.00 130.52 ? 197 HIS M CE1 1 ATOM 9719 N NE2 . HIS F 3 220 ? 105.043 20.837 -26.240 1.00 130.25 ? 197 HIS M NE2 1 ATOM 9720 N N . GLU F 3 221 ? 106.771 25.702 -24.071 1.00 134.69 ? 198 GLU M N 1 ATOM 9721 C CA . GLU F 3 221 ? 107.765 25.749 -23.004 1.00 136.39 ? 198 GLU M CA 1 ATOM 9722 C C . GLU F 3 221 ? 109.057 26.435 -23.439 1.00 137.06 ? 198 GLU M C 1 ATOM 9723 O O . GLU F 3 221 ? 110.075 25.780 -23.674 1.00 137.04 ? 198 GLU M O 1 ATOM 9724 C CB . GLU F 3 221 ? 108.077 24.338 -22.481 1.00 137.11 ? 198 GLU M CB 1 ATOM 9725 C CG . GLU F 3 221 ? 107.024 23.780 -21.519 1.00 138.30 ? 198 GLU M CG 1 ATOM 9726 C CD . GLU F 3 221 ? 107.527 22.591 -20.707 1.00 138.67 ? 198 GLU M CD 1 ATOM 9727 O OE1 . GLU F 3 221 ? 108.555 22.734 -20.009 1.00 138.41 ? 198 GLU M OE1 1 ATOM 9728 O OE2 . GLU F 3 221 ? 106.892 21.516 -20.758 1.00 139.07 ? 198 GLU M OE2 1 ATOM 9729 N N . GLY F 3 222 ? 109.000 27.759 -23.548 1.00 137.83 ? 199 GLY M N 1 ATOM 9730 C CA . GLY F 3 222 ? 110.169 28.529 -23.936 1.00 138.59 ? 199 GLY M CA 1 ATOM 9731 C C . GLY F 3 222 ? 110.276 28.906 -25.402 1.00 139.06 ? 199 GLY M C 1 ATOM 9732 O O . GLY F 3 222 ? 110.063 30.063 -25.776 1.00 139.14 ? 199 GLY M O 1 ATOM 9733 N N . SER F 3 223 ? 110.620 27.924 -26.231 1.00 139.19 ? 200 SER M N 1 ATOM 9734 C CA . SER F 3 223 ? 110.775 28.131 -27.666 1.00 139.26 ? 200 SER M CA 1 ATOM 9735 C C . SER F 3 223 ? 109.545 28.782 -28.301 1.00 138.85 ? 200 SER M C 1 ATOM 9736 O O . SER F 3 223 ? 108.453 28.216 -28.285 1.00 138.73 ? 200 SER M O 1 ATOM 9737 C CB . SER F 3 223 ? 111.060 26.791 -28.354 1.00 139.60 ? 200 SER M CB 1 ATOM 9738 O OG . SER F 3 223 ? 112.166 26.133 -27.756 1.00 139.61 ? 200 SER M OG 1 ATOM 9739 N N . THR F 3 224 ? 109.733 29.975 -28.857 1.00 138.53 ? 201 THR M N 1 ATOM 9740 C CA . THR F 3 224 ? 108.648 30.704 -29.506 1.00 137.96 ? 201 THR M CA 1 ATOM 9741 C C . THR F 3 224 ? 108.609 30.357 -30.997 1.00 137.68 ? 201 THR M C 1 ATOM 9742 O O . THR F 3 224 ? 108.723 31.238 -31.853 1.00 137.87 ? 201 THR M O 1 ATOM 9743 C CB . THR F 3 224 ? 108.826 32.238 -29.355 1.00 137.91 ? 201 THR M CB 1 ATOM 9744 O OG1 . THR F 3 224 ? 109.014 32.568 -27.973 1.00 138.14 ? 201 THR M OG1 1 ATOM 9745 C CG2 . THR F 3 224 ? 107.597 32.974 -29.874 1.00 137.50 ? 201 THR M CG2 1 ATOM 9746 N N . VAL F 3 225 ? 108.459 29.069 -31.299 1.00 137.03 ? 202 VAL M N 1 ATOM 9747 C CA . VAL F 3 225 ? 108.392 28.600 -32.682 1.00 136.22 ? 202 VAL M CA 1 ATOM 9748 C C . VAL F 3 225 ? 107.319 29.400 -33.416 1.00 136.18 ? 202 VAL M C 1 ATOM 9749 O O . VAL F 3 225 ? 106.181 29.478 -32.955 1.00 136.60 ? 202 VAL M O 1 ATOM 9750 C CB . VAL F 3 225 ? 108.019 27.100 -32.743 1.00 135.53 ? 202 VAL M CB 1 ATOM 9751 C CG1 . VAL F 3 225 ? 108.018 26.620 -34.184 1.00 134.94 ? 202 VAL M CG1 1 ATOM 9752 C CG2 . VAL F 3 225 ? 108.994 26.287 -31.911 1.00 135.44 ? 202 VAL M CG2 1 ATOM 9753 N N . GLU F 3 226 ? 107.676 29.994 -34.551 1.00 135.92 ? 203 GLU M N 1 ATOM 9754 C CA . GLU F 3 226 ? 106.717 30.792 -35.312 1.00 135.63 ? 203 GLU M CA 1 ATOM 9755 C C . GLU F 3 226 ? 106.978 30.822 -36.815 1.00 135.44 ? 203 GLU M C 1 ATOM 9756 O O . GLU F 3 226 ? 108.124 30.763 -37.263 1.00 135.56 ? 203 GLU M O 1 ATOM 9757 C CB . GLU F 3 226 ? 106.711 32.231 -34.800 1.00 135.54 ? 203 GLU M CB 1 ATOM 9758 C CG . GLU F 3 226 ? 108.019 32.958 -35.045 1.00 135.63 ? 203 GLU M CG 1 ATOM 9759 C CD . GLU F 3 226 ? 107.914 34.441 -34.791 1.00 136.01 ? 203 GLU M CD 1 ATOM 9760 O OE1 . GLU F 3 226 ? 107.102 35.101 -35.474 1.00 136.12 ? 203 GLU M OE1 1 ATOM 9761 O OE2 . GLU F 3 226 ? 108.641 34.946 -33.909 1.00 136.24 ? 203 GLU M OE2 1 ATOM 9762 N N . LYS F 3 227 ? 105.897 30.920 -37.583 1.00 134.82 ? 204 LYS M N 1 ATOM 9763 C CA . LYS F 3 227 ? 105.976 30.997 -39.036 1.00 133.78 ? 204 LYS M CA 1 ATOM 9764 C C . LYS F 3 227 ? 105.138 32.192 -39.465 1.00 133.58 ? 204 LYS M C 1 ATOM 9765 O O . LYS F 3 227 ? 104.499 32.833 -38.631 1.00 133.19 ? 204 LYS M O 1 ATOM 9766 C CB . LYS F 3 227 ? 105.452 29.710 -39.681 1.00 132.75 ? 204 LYS M CB 1 ATOM 9767 C CG . LYS F 3 227 ? 106.336 28.499 -39.419 1.00 131.67 ? 204 LYS M CG 1 ATOM 9768 C CD . LYS F 3 227 ? 105.891 27.282 -40.212 1.00 130.76 ? 204 LYS M CD 1 ATOM 9769 C CE . LYS F 3 227 ? 106.787 26.085 -39.917 1.00 129.83 ? 204 LYS M CE 1 ATOM 9770 N NZ . LYS F 3 227 ? 106.399 24.870 -40.688 1.00 129.02 ? 204 LYS M NZ 1 ATOM 9771 N N . THR F 3 228 ? 105.137 32.497 -40.758 1.00 133.55 ? 205 THR M N 1 ATOM 9772 C CA . THR F 3 228 ? 104.381 33.640 -41.249 1.00 133.62 ? 205 THR M CA 1 ATOM 9773 C C . THR F 3 228 ? 103.844 33.448 -42.661 1.00 133.72 ? 205 THR M C 1 ATOM 9774 O O . THR F 3 228 ? 104.349 32.634 -43.432 1.00 133.81 ? 205 THR M O 1 ATOM 9775 C CB . THR F 3 228 ? 105.254 34.915 -41.231 1.00 133.81 ? 205 THR M CB 1 ATOM 9776 O OG1 . THR F 3 228 ? 105.704 35.162 -39.895 1.00 134.24 ? 205 THR M OG1 1 ATOM 9777 C CG2 . THR F 3 228 ? 104.468 36.123 -41.723 1.00 133.77 ? 205 THR M CG2 1 ATOM 9778 N N . VAL F 3 229 ? 102.804 34.210 -42.978 1.00 134.06 ? 206 VAL M N 1 ATOM 9779 C CA . VAL F 3 229 ? 102.178 34.188 -44.290 1.00 134.65 ? 206 VAL M CA 1 ATOM 9780 C C . VAL F 3 229 ? 102.188 35.630 -44.781 1.00 135.14 ? 206 VAL M C 1 ATOM 9781 O O . VAL F 3 229 ? 102.152 36.558 -43.973 1.00 135.16 ? 206 VAL M O 1 ATOM 9782 C CB . VAL F 3 229 ? 100.728 33.682 -44.209 1.00 134.37 ? 206 VAL M CB 1 ATOM 9783 C CG1 . VAL F 3 229 ? 100.717 32.215 -43.839 1.00 134.76 ? 206 VAL M CG1 1 ATOM 9784 C CG2 . VAL F 3 229 ? 99.956 34.481 -43.176 1.00 134.47 ? 206 VAL M CG2 1 ATOM 9785 N N . ALA F 3 230 ? 102.244 35.823 -46.094 1.00 135.62 ? 207 ALA M N 1 ATOM 9786 C CA . ALA F 3 230 ? 102.279 37.170 -46.653 1.00 136.06 ? 207 ALA M CA 1 ATOM 9787 C C . ALA F 3 230 ? 101.200 37.383 -47.707 1.00 136.50 ? 207 ALA M C 1 ATOM 9788 O O . ALA F 3 230 ? 100.669 36.423 -48.261 1.00 136.58 ? 207 ALA M O 1 ATOM 9789 C CB . ALA F 3 230 ? 103.656 37.441 -47.253 1.00 136.24 ? 207 ALA M CB 1 ATOM 9790 N N . PRO F 3 231 ? 100.858 38.653 -47.994 1.00 137.05 ? 208 PRO M N 1 ATOM 9791 C CA . PRO F 3 231 ? 99.834 38.951 -48.999 1.00 137.47 ? 208 PRO M CA 1 ATOM 9792 C C . PRO F 3 231 ? 100.319 38.574 -50.397 1.00 138.07 ? 208 PRO M C 1 ATOM 9793 O O . PRO F 3 231 ? 99.737 38.982 -51.402 1.00 137.94 ? 208 PRO M O 1 ATOM 9794 C CB . PRO F 3 231 ? 99.618 40.453 -48.834 1.00 137.39 ? 208 PRO M CB 1 ATOM 9795 C CG . PRO F 3 231 ? 100.971 40.935 -48.421 1.00 137.39 ? 208 PRO M CG 1 ATOM 9796 C CD . PRO F 3 231 ? 101.385 39.896 -47.403 1.00 137.28 ? 208 PRO M CD 1 ATOM 9797 N N . THR F 3 232 ? 101.396 37.792 -50.439 1.00 138.86 ? 209 THR M N 1 ATOM 9798 C CA . THR F 3 232 ? 101.985 37.323 -51.689 1.00 139.21 ? 209 THR M CA 1 ATOM 9799 C C . THR F 3 232 ? 100.939 36.539 -52.478 1.00 139.82 ? 209 THR M C 1 ATOM 9800 O O . THR F 3 232 ? 100.303 35.631 -51.940 1.00 139.98 ? 209 THR M O 1 ATOM 9801 C CB . THR F 3 232 ? 103.195 36.401 -51.418 1.00 138.84 ? 209 THR M CB 1 ATOM 9802 O OG1 . THR F 3 232 ? 102.763 35.238 -50.698 1.00 137.88 ? 209 THR M OG1 1 ATOM 9803 C CG2 . THR F 3 232 ? 104.251 37.135 -50.600 1.00 138.25 ? 209 THR M CG2 1 ATOM 9804 N N . GLU F 3 233 ? 100.767 36.882 -53.751 1.00 140.10 ? 210 GLU M N 1 ATOM 9805 C CA . GLU F 3 233 ? 99.779 36.205 -54.579 1.00 140.41 ? 210 GLU M CA 1 ATOM 9806 C C . GLU F 3 233 ? 100.303 34.929 -55.226 1.00 140.33 ? 210 GLU M C 1 ATOM 9807 O O . GLU F 3 233 ? 100.063 34.675 -56.407 1.00 139.68 ? 210 GLU M O 1 ATOM 9808 C CB . GLU F 3 233 ? 99.255 37.154 -55.654 1.00 140.80 ? 210 GLU M CB 1 ATOM 9809 C CG . GLU F 3 233 ? 97.748 37.098 -55.804 1.00 141.72 ? 210 GLU M CG 1 ATOM 9810 C CD . GLU F 3 233 ? 97.029 37.405 -54.501 1.00 142.40 ? 210 GLU M CD 1 ATOM 9811 O OE1 . GLU F 3 233 ? 97.215 38.519 -53.967 1.00 142.75 ? 210 GLU M OE1 1 ATOM 9812 O OE2 . GLU F 3 233 ? 96.281 36.533 -54.008 1.00 142.54 ? 210 GLU M OE2 1 ATOM 9813 N N . CYS F 3 234 ? 101.018 34.129 -54.439 1.00 140.56 ? 211 CYS M N 1 ATOM 9814 C CA . CYS F 3 234 ? 101.571 32.863 -54.907 1.00 140.55 ? 211 CYS M CA 1 ATOM 9815 C C . CYS F 3 234 ? 102.065 32.041 -53.721 1.00 140.35 ? 211 CYS M C 1 ATOM 9816 O O . CYS F 3 234 ? 102.034 32.566 -52.588 1.00 140.28 ? 211 CYS M O 1 ATOM 9817 C CB . CYS F 3 234 ? 102.729 33.105 -55.882 1.00 141.08 ? 211 CYS M CB 1 ATOM 9818 S SG . CYS F 3 234 ? 104.229 33.802 -55.145 1.00 141.32 ? 211 CYS M SG 1 ATOM 9819 O OXT . CYS F 3 234 ? 102.479 30.884 -53.939 1.00 139.92 ? 211 CYS M OXT 1 HETATM 9820 CD CD . CD G 4 . ? 69.494 5.878 47.185 1.00 57.66 ? 1445 CD A CD 1 HETATM 9821 ZN ZN . ZN H 5 . ? 71.339 -1.838 36.083 1.00 43.68 ? 1446 ZN A ZN 1 HETATM 9822 AS AS . CAC I 6 . ? 72.014 -3.404 33.658 1.00 87.38 ? 1447 CAC A AS 1 HETATM 9823 O O1 . CAC I 6 . ? 70.730 -3.782 34.338 1.00 84.51 ? 1447 CAC A O1 1 HETATM 9824 O O2 . CAC I 6 . ? 72.111 -2.010 33.109 1.00 83.04 ? 1447 CAC A O2 1 HETATM 9825 C C1 . CAC I 6 . ? 72.308 -4.564 32.340 1.00 84.94 ? 1447 CAC A C1 1 HETATM 9826 C C2 . CAC I 6 . ? 73.362 -3.668 34.791 1.00 84.84 ? 1447 CAC A C2 1 HETATM 9827 C C1 . MPD J 7 . ? 55.191 32.419 59.404 1.00 96.53 ? 1448 MPD A C1 1 HETATM 9828 C C2 . MPD J 7 . ? 54.082 33.274 59.966 1.00 95.92 ? 1448 MPD A C2 1 HETATM 9829 O O2 . MPD J 7 . ? 53.958 32.890 61.345 1.00 98.57 ? 1448 MPD A O2 1 HETATM 9830 C CM . MPD J 7 . ? 54.414 34.726 59.879 1.00 96.18 ? 1448 MPD A CM 1 HETATM 9831 C C3 . MPD J 7 . ? 52.719 33.028 59.261 1.00 95.12 ? 1448 MPD A C3 1 HETATM 9832 C C4 . MPD J 7 . ? 51.843 31.845 59.720 1.00 93.98 ? 1448 MPD A C4 1 HETATM 9833 O O4 . MPD J 7 . ? 51.434 31.976 61.058 1.00 92.92 ? 1448 MPD A O4 1 HETATM 9834 C C5 . MPD J 7 . ? 50.585 31.767 58.906 1.00 94.34 ? 1448 MPD A C5 1 HETATM 9835 C C1 . MPD K 7 . ? 65.055 19.495 37.422 1.00 86.95 ? 1449 MPD A C1 1 HETATM 9836 C C2 . MPD K 7 . ? 64.794 18.193 36.679 1.00 85.05 ? 1449 MPD A C2 1 HETATM 9837 O O2 . MPD K 7 . ? 65.625 17.206 37.314 1.00 83.98 ? 1449 MPD A O2 1 HETATM 9838 C CM . MPD K 7 . ? 63.364 17.796 36.790 1.00 84.83 ? 1449 MPD A CM 1 HETATM 9839 C C3 . MPD K 7 . ? 65.157 18.225 35.159 1.00 84.87 ? 1449 MPD A C3 1 HETATM 9840 C C4 . MPD K 7 . ? 66.480 18.866 34.696 1.00 83.30 ? 1449 MPD A C4 1 HETATM 9841 O O4 . MPD K 7 . ? 67.603 18.208 35.235 1.00 82.50 ? 1449 MPD A O4 1 HETATM 9842 C C5 . MPD K 7 . ? 66.620 18.808 33.182 1.00 81.97 ? 1449 MPD A C5 1 HETATM 9843 C C1 . MPD L 7 . ? 62.702 18.475 32.449 1.00 81.57 ? 1450 MPD A C1 1 HETATM 9844 C C2 . MPD L 7 . ? 62.184 17.076 32.672 1.00 81.57 ? 1450 MPD A C2 1 HETATM 9845 O O2 . MPD L 7 . ? 61.564 16.682 31.439 1.00 81.57 ? 1450 MPD A O2 1 HETATM 9846 C CM . MPD L 7 . ? 63.273 16.127 32.989 1.00 81.57 ? 1450 MPD A CM 1 HETATM 9847 C C3 . MPD L 7 . ? 61.091 16.953 33.781 1.00 81.57 ? 1450 MPD A C3 1 HETATM 9848 C C4 . MPD L 7 . ? 60.140 18.159 34.073 1.00 81.57 ? 1450 MPD A C4 1 HETATM 9849 O O4 . MPD L 7 . ? 59.390 18.588 32.941 1.00 81.57 ? 1450 MPD A O4 1 HETATM 9850 C C5 . MPD L 7 . ? 59.152 17.808 35.162 1.00 81.57 ? 1450 MPD A C5 1 HETATM 9851 C C . ACT M 8 . ? 58.377 1.120 23.522 1.00 66.16 ? 1451 ACT A C 1 HETATM 9852 O O . ACT M 8 . ? 57.472 1.026 24.478 1.00 64.75 ? 1451 ACT A O 1 HETATM 9853 O OXT . ACT M 8 . ? 58.175 0.967 22.265 1.00 65.70 ? 1451 ACT A OXT 1 HETATM 9854 C CH3 . ACT M 8 . ? 59.805 1.430 23.833 1.00 65.76 ? 1451 ACT A CH3 1 HETATM 9855 C C . ACT N 8 . ? 61.080 13.441 58.503 1.00 85.64 ? 1452 ACT A C 1 HETATM 9856 O O . ACT N 8 . ? 61.263 13.354 57.203 1.00 85.49 ? 1452 ACT A O 1 HETATM 9857 O OXT . ACT N 8 . ? 60.167 14.109 59.086 1.00 85.35 ? 1452 ACT A OXT 1 HETATM 9858 C CH3 . ACT N 8 . ? 61.973 12.726 59.472 1.00 85.15 ? 1452 ACT A CH3 1 HETATM 9859 C C1 . NAG O 9 . ? 46.560 35.987 44.856 1.00 32.95 ? 1453 NAG A C1 1 HETATM 9860 C C2 . NAG O 9 . ? 45.493 35.036 44.312 1.00 32.52 ? 1453 NAG A C2 1 HETATM 9861 C C3 . NAG O 9 . ? 45.887 33.574 44.537 1.00 34.41 ? 1453 NAG A C3 1 HETATM 9862 C C4 . NAG O 9 . ? 47.296 33.339 43.975 1.00 33.65 ? 1453 NAG A C4 1 HETATM 9863 C C5 . NAG O 9 . ? 48.241 34.286 44.646 1.00 34.31 ? 1453 NAG A C5 1 HETATM 9864 C C6 . NAG O 9 . ? 49.637 34.023 44.120 1.00 38.24 ? 1453 NAG A C6 1 HETATM 9865 C C7 . NAG O 9 . ? 43.131 35.476 44.269 1.00 36.97 ? 1453 NAG A C7 1 HETATM 9866 C C8 . NAG O 9 . ? 41.867 34.763 44.715 1.00 34.86 ? 1453 NAG A C8 1 HETATM 9867 N N2 . NAG O 9 . ? 44.237 35.295 44.980 1.00 36.40 ? 1453 NAG A N2 1 HETATM 9868 O O3 . NAG O 9 . ? 44.940 32.720 43.904 1.00 33.39 ? 1453 NAG A O3 1 HETATM 9869 O O4 . NAG O 9 . ? 47.749 32.005 44.231 1.00 33.47 ? 1453 NAG A O4 1 HETATM 9870 O O5 . NAG O 9 . ? 47.854 35.642 44.341 1.00 34.03 ? 1453 NAG A O5 1 HETATM 9871 O O6 . NAG O 9 . ? 50.361 35.244 43.906 1.00 45.20 ? 1453 NAG A O6 1 HETATM 9872 O O7 . NAG O 9 . ? 43.103 36.187 43.273 1.00 40.24 ? 1453 NAG A O7 1 HETATM 9873 C C1 . FUL P 10 . ? 49.931 35.908 42.765 1.00 46.24 ? 1454 FUL A C1 1 HETATM 9874 C C2 . FUL P 10 . ? 50.654 35.393 41.518 1.00 47.42 ? 1454 FUL A C2 1 HETATM 9875 O O2 . FUL P 10 . ? 50.457 33.992 41.387 1.00 49.80 ? 1454 FUL A O2 1 HETATM 9876 C C3 . FUL P 10 . ? 50.051 36.116 40.318 1.00 48.61 ? 1454 FUL A C3 1 HETATM 9877 O O3 . FUL P 10 . ? 50.628 35.651 39.105 1.00 45.97 ? 1454 FUL A O3 1 HETATM 9878 C C4 . FUL P 10 . ? 50.287 37.618 40.510 1.00 50.08 ? 1454 FUL A C4 1 HETATM 9879 O O4 . FUL P 10 . ? 51.679 37.845 40.703 1.00 51.89 ? 1454 FUL A O4 1 HETATM 9880 C C5 . FUL P 10 . ? 49.536 38.045 41.775 1.00 50.73 ? 1454 FUL A C5 1 HETATM 9881 C C6 . FUL P 10 . ? 49.655 39.521 42.112 1.00 51.87 ? 1454 FUL A C6 1 HETATM 9882 O O5 . FUL P 10 . ? 50.062 37.313 42.890 1.00 48.44 ? 1454 FUL A O5 1 HETATM 9883 C C1 . NAG Q 9 . ? 47.833 31.162 43.144 1.00 35.44 ? 1455 NAG A C1 1 HETATM 9884 C C2 . NAG Q 9 . ? 49.127 30.352 43.230 1.00 35.25 ? 1455 NAG A C2 1 HETATM 9885 C C3 . NAG Q 9 . ? 49.172 29.297 42.139 1.00 36.70 ? 1455 NAG A C3 1 HETATM 9886 C C4 . NAG Q 9 . ? 47.912 28.408 42.245 1.00 37.89 ? 1455 NAG A C4 1 HETATM 9887 C C5 . NAG Q 9 . ? 46.681 29.309 42.170 1.00 37.68 ? 1455 NAG A C5 1 HETATM 9888 C C6 . NAG Q 9 . ? 45.373 28.570 42.311 1.00 39.44 ? 1455 NAG A C6 1 HETATM 9889 C C7 . NAG Q 9 . ? 51.263 31.148 44.012 1.00 35.71 ? 1455 NAG A C7 1 HETATM 9890 C C8 . NAG Q 9 . ? 50.963 30.619 45.409 1.00 38.34 ? 1455 NAG A C8 1 HETATM 9891 N N2 . NAG Q 9 . ? 50.277 31.220 43.120 1.00 34.44 ? 1455 NAG A N2 1 HETATM 9892 O O3 . NAG Q 9 . ? 50.358 28.535 42.300 1.00 37.16 ? 1455 NAG A O3 1 HETATM 9893 O O4 . NAG Q 9 . ? 47.859 27.458 41.164 1.00 40.34 ? 1455 NAG A O4 1 HETATM 9894 O O5 . NAG Q 9 . ? 46.708 30.287 43.220 1.00 36.08 ? 1455 NAG A O5 1 HETATM 9895 O O6 . NAG Q 9 . ? 44.307 29.477 42.558 1.00 39.54 ? 1455 NAG A O6 1 HETATM 9896 O O7 . NAG Q 9 . ? 52.398 31.514 43.754 1.00 36.86 ? 1455 NAG A O7 1 HETATM 9897 C C1 . BMA R 11 . ? 48.386 26.195 41.387 1.00 45.98 ? 1456 BMA A C1 1 HETATM 9898 C C2 . BMA R 11 . ? 47.589 25.171 40.564 1.00 48.84 ? 1456 BMA A C2 1 HETATM 9899 C C3 . BMA R 11 . ? 48.280 23.800 40.618 1.00 50.77 ? 1456 BMA A C3 1 HETATM 9900 C C4 . BMA R 11 . ? 49.695 23.950 40.141 1.00 47.84 ? 1456 BMA A C4 1 HETATM 9901 C C5 . BMA R 11 . ? 50.410 24.935 41.029 1.00 48.14 ? 1456 BMA A C5 1 HETATM 9902 C C6 . BMA R 11 . ? 51.834 25.121 40.577 1.00 48.85 ? 1456 BMA A C6 1 HETATM 9903 O O2 . BMA R 11 . ? 47.518 25.619 39.223 1.00 46.38 ? 1456 BMA A O2 1 HETATM 9904 O O3 . BMA R 11 . ? 47.645 22.837 39.761 1.00 62.10 ? 1456 BMA A O3 1 HETATM 9905 O O4 . BMA R 11 . ? 50.347 22.695 40.163 1.00 45.63 ? 1456 BMA A O4 1 HETATM 9906 O O5 . BMA R 11 . ? 49.762 26.222 40.955 1.00 46.37 ? 1456 BMA A O5 1 HETATM 9907 O O6 . BMA R 11 . ? 52.581 25.749 41.626 1.00 51.24 ? 1456 BMA A O6 1 HETATM 9908 C C1 . MAN S 12 . ? 53.503 26.639 41.101 1.00 51.38 ? 1457 MAN A C1 1 HETATM 9909 C C2 . MAN S 12 . ? 54.412 27.161 42.200 1.00 49.83 ? 1457 MAN A C2 1 HETATM 9910 C C3 . MAN S 12 . ? 54.264 28.680 42.334 1.00 49.93 ? 1457 MAN A C3 1 HETATM 9911 C C4 . MAN S 12 . ? 54.569 29.372 41.004 1.00 51.25 ? 1457 MAN A C4 1 HETATM 9912 C C5 . MAN S 12 . ? 53.801 28.689 39.866 1.00 52.91 ? 1457 MAN A C5 1 HETATM 9913 C C6 . MAN S 12 . ? 54.694 27.972 38.856 1.00 51.46 ? 1457 MAN A C6 1 HETATM 9914 O O2 . MAN S 12 . ? 55.757 26.834 41.834 1.00 49.70 ? 1457 MAN A O2 1 HETATM 9915 O O3 . MAN S 12 . ? 55.146 29.164 43.328 1.00 51.34 ? 1457 MAN A O3 1 HETATM 9916 O O4 . MAN S 12 . ? 54.208 30.748 41.075 1.00 49.54 ? 1457 MAN A O4 1 HETATM 9917 O O5 . MAN S 12 . ? 52.882 27.713 40.407 1.00 54.18 ? 1457 MAN A O5 1 HETATM 9918 O O6 . MAN S 12 . ? 54.069 27.896 37.580 1.00 50.63 ? 1457 MAN A O6 1 HETATM 9919 C C1 . NDG T 13 . ? 56.638 26.431 42.825 1.00 51.60 ? 1458 NDG A C1 1 HETATM 9920 C C2 . NDG T 13 . ? 57.869 25.787 42.164 1.00 51.24 ? 1458 NDG A C2 1 HETATM 9921 C C3 . NDG T 13 . ? 58.295 24.507 42.872 1.00 50.31 ? 1458 NDG A C3 1 HETATM 9922 C C4 . NDG T 13 . ? 58.213 24.742 44.378 1.00 50.20 ? 1458 NDG A C4 1 HETATM 9923 C C5 . NDG T 13 . ? 56.782 25.028 44.800 1.00 50.73 ? 1458 NDG A C5 1 HETATM 9924 C C6 . NDG T 13 . ? 56.763 26.058 45.897 1.00 51.34 ? 1458 NDG A C6 1 HETATM 9925 C C7 . NDG T 13 . ? 57.948 26.460 39.867 1.00 57.22 ? 1458 NDG A C7 1 HETATM 9926 C C8 . NDG T 13 . ? 58.990 26.096 38.817 1.00 56.42 ? 1458 NDG A C8 1 HETATM 9927 O O . NDG T 13 . ? 55.965 25.501 43.690 1.00 50.51 ? 1458 NDG A O 1 HETATM 9928 O O3 . NDG T 13 . ? 59.624 24.207 42.497 1.00 50.28 ? 1458 NDG A O3 1 HETATM 9929 O O4 . NDG T 13 . ? 58.668 23.600 45.128 1.00 53.06 ? 1458 NDG A O4 1 HETATM 9930 O O6 . NDG T 13 . ? 57.914 25.921 46.721 1.00 50.24 ? 1458 NDG A O6 1 HETATM 9931 O O7 . NDG T 13 . ? 57.470 27.596 39.881 1.00 59.16 ? 1458 NDG A O7 1 HETATM 9932 N N2 . NDG T 13 . ? 57.611 25.532 40.761 1.00 53.86 ? 1458 NDG A N2 1 HETATM 9933 C C1 . GAL U 14 . ? 60.000 23.214 45.114 1.00 55.55 ? 1459 GAL A C1 1 HETATM 9934 C C2 . GAL U 14 . ? 60.937 24.419 45.307 1.00 57.40 ? 1459 GAL A C2 1 HETATM 9935 C C3 . GAL U 14 . ? 62.379 23.926 45.371 1.00 56.53 ? 1459 GAL A C3 1 HETATM 9936 C C4 . GAL U 14 . ? 62.503 22.876 46.465 1.00 56.75 ? 1459 GAL A C4 1 HETATM 9937 C C5 . GAL U 14 . ? 61.531 21.747 46.208 1.00 56.57 ? 1459 GAL A C5 1 HETATM 9938 C C6 . GAL U 14 . ? 61.599 20.734 47.322 1.00 57.27 ? 1459 GAL A C6 1 HETATM 9939 O O2 . GAL U 14 . ? 60.795 25.345 44.232 1.00 61.64 ? 1459 GAL A O2 1 HETATM 9940 O O3 . GAL U 14 . ? 63.231 25.023 45.656 1.00 55.08 ? 1459 GAL A O3 1 HETATM 9941 O O4 . GAL U 14 . ? 62.177 23.459 47.718 1.00 61.86 ? 1459 GAL A O4 1 HETATM 9942 O O5 . GAL U 14 . ? 60.188 22.265 46.180 1.00 53.42 ? 1459 GAL A O5 1 HETATM 9943 O O6 . GAL U 14 . ? 62.930 20.263 47.504 1.00 57.62 ? 1459 GAL A O6 1 HETATM 9944 C C1 . BMA V 11 . ? 46.256 22.747 39.644 1.00 71.83 ? 1460 BMA A C1 1 HETATM 9945 C C2 . BMA V 11 . ? 45.923 21.342 39.110 1.00 76.40 ? 1460 BMA A C2 1 HETATM 9946 C C3 . BMA V 11 . ? 44.405 21.075 39.142 1.00 78.18 ? 1460 BMA A C3 1 HETATM 9947 C C4 . BMA V 11 . ? 43.820 21.414 40.520 1.00 79.64 ? 1460 BMA A C4 1 HETATM 9948 C C5 . BMA V 11 . ? 44.162 22.871 40.782 1.00 78.48 ? 1460 BMA A C5 1 HETATM 9949 C C6 . BMA V 11 . ? 43.542 23.489 42.019 1.00 79.44 ? 1460 BMA A C6 1 HETATM 9950 O O2 . BMA V 11 . ? 46.693 20.368 39.869 1.00 83.17 ? 1460 BMA A O2 1 HETATM 9951 O O3 . BMA V 11 . ? 44.132 19.727 38.800 1.00 78.75 ? 1460 BMA A O3 1 HETATM 9952 O O4 . BMA V 11 . ? 42.410 21.223 40.530 1.00 82.59 ? 1460 BMA A O4 1 HETATM 9953 O O5 . BMA V 11 . ? 45.590 22.997 40.876 1.00 73.91 ? 1460 BMA A O5 1 HETATM 9954 O O6 . BMA V 11 . ? 42.991 24.767 41.721 1.00 79.41 ? 1460 BMA A O6 1 HETATM 9955 C C1 . NAG W 9 . ? 46.189 19.146 40.312 1.00 88.53 ? 1461 NAG A C1 1 HETATM 9956 C C2 . NAG W 9 . ? 47.339 18.127 40.338 1.00 90.02 ? 1461 NAG A C2 1 HETATM 9957 C C3 . NAG W 9 . ? 46.835 16.791 40.871 1.00 90.70 ? 1461 NAG A C3 1 HETATM 9958 C C4 . NAG W 9 . ? 46.272 17.006 42.275 1.00 91.24 ? 1461 NAG A C4 1 HETATM 9959 C C5 . NAG W 9 . ? 45.189 18.109 42.270 1.00 91.22 ? 1461 NAG A C5 1 HETATM 9960 C C6 . NAG W 9 . ? 44.741 18.476 43.683 1.00 91.92 ? 1461 NAG A C6 1 HETATM 9961 C C7 . NAG W 9 . ? 49.255 17.901 38.904 1.00 92.93 ? 1461 NAG A C7 1 HETATM 9962 C C8 . NAG W 9 . ? 49.956 19.118 38.312 1.00 92.35 ? 1461 NAG A C8 1 HETATM 9963 N N2 . NAG W 9 . ? 47.930 17.957 39.025 1.00 91.65 ? 1461 NAG A N2 1 HETATM 9964 O O3 . NAG W 9 . ? 47.906 15.856 40.913 1.00 90.85 ? 1461 NAG A O3 1 HETATM 9965 O O4 . NAG W 9 . ? 45.720 15.789 42.762 1.00 91.22 ? 1461 NAG A O4 1 HETATM 9966 O O5 . NAG W 9 . ? 45.686 19.334 41.655 1.00 89.91 ? 1461 NAG A O5 1 HETATM 9967 O O6 . NAG W 9 . ? 45.323 17.622 44.666 1.00 91.03 ? 1461 NAG A O6 1 HETATM 9968 O O7 . NAG W 9 . ? 49.919 16.921 39.259 1.00 92.87 ? 1461 NAG A O7 1 HETATM 9969 ZN ZN . ZN X 5 . ? 23.682 10.150 38.735 1.00 143.96 ? 1446 ZN B ZN 1 HETATM 9970 C C1 . MPD Y 7 . ? 53.505 28.381 1.338 1.00 81.86 ? 1447 MPD B C1 1 HETATM 9971 C C2 . MPD Y 7 . ? 54.661 29.011 0.586 1.00 83.58 ? 1447 MPD B C2 1 HETATM 9972 O O2 . MPD Y 7 . ? 55.534 27.925 0.216 1.00 82.69 ? 1447 MPD B O2 1 HETATM 9973 C CM . MPD Y 7 . ? 54.192 29.718 -0.644 1.00 83.88 ? 1447 MPD B CM 1 HETATM 9974 C C3 . MPD Y 7 . ? 55.471 30.014 1.454 1.00 83.24 ? 1447 MPD B C3 1 HETATM 9975 C C4 . MPD Y 7 . ? 56.396 29.445 2.543 1.00 83.59 ? 1447 MPD B C4 1 HETATM 9976 O O4 . MPD Y 7 . ? 57.412 28.621 1.998 1.00 81.32 ? 1447 MPD B O4 1 HETATM 9977 C C5 . MPD Y 7 . ? 57.092 30.564 3.306 1.00 84.13 ? 1447 MPD B C5 1 HETATM 9978 C C1 . MPD Z 7 . ? 51.620 12.337 20.125 1.00 84.58 ? 1448 MPD B C1 1 HETATM 9979 C C2 . MPD Z 7 . ? 51.321 10.916 20.550 1.00 84.51 ? 1448 MPD B C2 1 HETATM 9980 O O2 . MPD Z 7 . ? 52.600 10.333 20.868 1.00 83.27 ? 1448 MPD B O2 1 HETATM 9981 C CM . MPD Z 7 . ? 50.426 10.895 21.749 1.00 84.39 ? 1448 MPD B CM 1 HETATM 9982 C C3 . MPD Z 7 . ? 50.668 10.081 19.404 1.00 83.71 ? 1448 MPD B C3 1 HETATM 9983 C C4 . MPD Z 7 . ? 51.008 8.581 19.293 1.00 83.00 ? 1448 MPD B C4 1 HETATM 9984 O O4 . MPD Z 7 . ? 50.637 7.861 20.454 1.00 82.65 ? 1448 MPD B O4 1 HETATM 9985 C C5 . MPD Z 7 . ? 50.284 7.944 18.114 1.00 82.47 ? 1448 MPD B C5 1 HETATM 9986 C C . ACT AA 8 . ? 66.156 20.137 6.787 1.00 81.57 ? 1449 ACT B C 1 HETATM 9987 O O . ACT AA 8 . ? 65.567 20.611 7.862 1.00 81.57 ? 1449 ACT B O 1 HETATM 9988 O OXT . ACT AA 8 . ? 67.397 19.888 6.654 1.00 81.57 ? 1449 ACT B OXT 1 HETATM 9989 C CH3 . ACT AA 8 . ? 65.384 19.834 5.551 1.00 81.57 ? 1449 ACT B CH3 1 HETATM 9990 C C1 . NAG BA 9 . ? 35.492 14.487 38.035 1.00 123.64 ? 1450 NAG B C1 1 HETATM 9991 C C2 . NAG BA 9 . ? 36.683 15.273 38.602 1.00 122.59 ? 1450 NAG B C2 1 HETATM 9992 C C3 . NAG BA 9 . ? 37.054 16.413 37.645 1.00 122.84 ? 1450 NAG B C3 1 HETATM 9993 C C4 . NAG BA 9 . ? 37.348 15.841 36.250 1.00 122.81 ? 1450 NAG B C4 1 HETATM 9994 C C5 . NAG BA 9 . ? 36.133 15.036 35.773 1.00 122.47 ? 1450 NAG B C5 1 HETATM 9995 C C6 . NAG BA 9 . ? 36.413 14.362 34.438 1.00 122.06 ? 1450 NAG B C6 1 HETATM 9996 C C7 . NAG BA 9 . ? 37.268 15.823 40.875 1.00 119.63 ? 1450 NAG B C7 1 HETATM 9997 C C8 . NAG BA 9 . ? 37.838 17.177 41.265 1.00 119.15 ? 1450 NAG B C8 1 HETATM 9998 N N2 . NAG BA 9 . ? 36.353 15.803 39.911 1.00 120.86 ? 1450 NAG B N2 1 HETATM 9999 O O3 . NAG BA 9 . ? 38.191 17.104 38.140 1.00 122.90 ? 1450 NAG B O3 1 HETATM 10000 O O4 . NAG BA 9 . ? 37.635 16.904 35.306 1.00 123.12 ? 1450 NAG B O4 1 HETATM 10001 O O5 . NAG BA 9 . ? 35.806 13.992 36.725 1.00 123.36 ? 1450 NAG B O5 1 HETATM 10002 O O6 . NAG BA 9 . ? 36.452 12.924 34.585 1.00 121.63 ? 1450 NAG B O6 1 HETATM 10003 O O7 . NAG BA 9 . ? 37.659 14.805 41.445 1.00 118.81 ? 1450 NAG B O7 1 HETATM 10004 C C1 . FUL CA 10 . ? 37.592 12.442 35.254 1.00 120.75 ? 1451 FUL B C1 1 HETATM 10005 C C2 . FUL CA 10 . ? 38.826 12.546 34.335 1.00 119.99 ? 1451 FUL B C2 1 HETATM 10006 O O2 . FUL CA 10 . ? 39.127 13.910 34.081 1.00 119.31 ? 1451 FUL B O2 1 HETATM 10007 C C3 . FUL CA 10 . ? 40.048 11.885 34.963 1.00 119.53 ? 1451 FUL B C3 1 HETATM 10008 O O3 . FUL CA 10 . ? 41.099 11.853 34.011 1.00 119.19 ? 1451 FUL B O3 1 HETATM 10009 C C4 . FUL CA 10 . ? 39.716 10.461 35.417 1.00 119.56 ? 1451 FUL B C4 1 HETATM 10010 O O4 . FUL CA 10 . ? 39.397 9.660 34.288 1.00 119.01 ? 1451 FUL B O4 1 HETATM 10011 C C5 . FUL CA 10 . ? 38.522 10.503 36.365 1.00 119.49 ? 1451 FUL B C5 1 HETATM 10012 C C6 . FUL CA 10 . ? 38.092 9.121 36.815 1.00 119.33 ? 1451 FUL B C6 1 HETATM 10013 O O5 . FUL CA 10 . ? 37.396 11.096 35.693 1.00 120.17 ? 1451 FUL B O5 1 HETATM 10014 C C1 . NAG DA 9 . ? 38.966 17.080 34.932 1.00 123.36 ? 1452 NAG B C1 1 HETATM 10015 C C2 . NAG DA 9 . ? 39.045 17.651 33.504 1.00 123.56 ? 1452 NAG B C2 1 HETATM 10016 C C3 . NAG DA 9 . ? 40.482 18.073 33.137 1.00 122.96 ? 1452 NAG B C3 1 HETATM 10017 C C4 . NAG DA 9 . ? 41.145 18.911 34.247 1.00 122.04 ? 1452 NAG B C4 1 HETATM 10018 C C5 . NAG DA 9 . ? 40.972 18.200 35.592 1.00 122.33 ? 1452 NAG B C5 1 HETATM 10019 C C6 . NAG DA 9 . ? 41.554 18.969 36.763 1.00 121.45 ? 1452 NAG B C6 1 HETATM 10020 C C7 . NAG DA 9 . ? 37.615 16.926 31.697 1.00 126.24 ? 1452 NAG B C7 1 HETATM 10021 C C8 . NAG DA 9 . ? 37.984 17.676 30.423 1.00 126.43 ? 1452 NAG B C8 1 HETATM 10022 N N2 . NAG DA 9 . ? 38.594 16.650 32.554 1.00 124.92 ? 1452 NAG B N2 1 HETATM 10023 O O3 . NAG DA 9 . ? 40.458 18.823 31.930 1.00 122.88 ? 1452 NAG B O3 1 HETATM 10024 O O4 . NAG DA 9 . ? 42.557 19.067 33.975 1.00 120.22 ? 1452 NAG B O4 1 HETATM 10025 O O5 . NAG DA 9 . ? 39.570 17.991 35.862 1.00 123.59 ? 1452 NAG B O5 1 HETATM 10026 O O6 . NAG DA 9 . ? 40.679 20.001 37.188 1.00 120.75 ? 1452 NAG B O6 1 HETATM 10027 O O7 . NAG DA 9 . ? 36.445 16.593 31.892 1.00 126.46 ? 1452 NAG B O7 1 HETATM 10028 C C1 . BMA EA 11 . ? 42.937 19.991 33.011 1.00 119.63 ? 1453 BMA B C1 1 HETATM 10029 C C2 . BMA EA 11 . ? 44.002 20.933 33.584 1.00 119.50 ? 1453 BMA B C2 1 HETATM 10030 C C3 . BMA EA 11 . ? 44.453 21.907 32.489 1.00 118.62 ? 1453 BMA B C3 1 HETATM 10031 C C4 . BMA EA 11 . ? 44.967 21.122 31.284 1.00 117.76 ? 1453 BMA B C4 1 HETATM 10032 C C5 . BMA EA 11 . ? 43.899 20.126 30.809 1.00 117.09 ? 1453 BMA B C5 1 HETATM 10033 C C6 . BMA EA 11 . ? 44.398 19.221 29.693 1.00 115.22 ? 1453 BMA B C6 1 HETATM 10034 O O2 . BMA EA 11 . ? 45.116 20.174 34.037 1.00 120.15 ? 1453 BMA B O2 1 HETATM 10035 O O3 . BMA EA 11 . ? 45.497 22.781 32.975 1.00 118.29 ? 1453 BMA B O3 1 HETATM 10036 O O4 . BMA EA 11 . ? 45.287 22.023 30.235 1.00 117.27 ? 1453 BMA B O4 1 HETATM 10037 O O5 . BMA EA 11 . ? 43.488 19.266 31.899 1.00 118.55 ? 1453 BMA B O5 1 HETATM 10038 O O6 . BMA EA 11 . ? 43.283 18.814 28.873 1.00 112.38 ? 1453 BMA B O6 1 HETATM 10039 C C1 . MAN FA 12 . ? 43.011 17.439 28.919 1.00 110.56 ? 1454 MAN B C1 1 HETATM 10040 C C2 . MAN FA 12 . ? 41.581 17.204 28.406 1.00 110.06 ? 1454 MAN B C2 1 HETATM 10041 C C3 . MAN FA 12 . ? 40.757 16.365 29.392 1.00 109.63 ? 1454 MAN B C3 1 HETATM 10042 C C4 . MAN FA 12 . ? 41.526 15.112 29.826 1.00 109.54 ? 1454 MAN B C4 1 HETATM 10043 C C5 . MAN FA 12 . ? 42.919 15.471 30.360 1.00 109.36 ? 1454 MAN B C5 1 HETATM 10044 C C6 . MAN FA 12 . ? 44.048 14.734 29.666 1.00 109.43 ? 1454 MAN B C6 1 HETATM 10045 O O2 . MAN FA 12 . ? 41.618 16.565 27.113 1.00 108.50 ? 1454 MAN B O2 1 HETATM 10046 O O3 . MAN FA 12 . ? 39.523 15.993 28.796 1.00 109.65 ? 1454 MAN B O3 1 HETATM 10047 O O4 . MAN FA 12 . ? 40.798 14.442 30.844 1.00 109.17 ? 1454 MAN B O4 1 HETATM 10048 O O5 . MAN FA 12 . ? 43.174 16.892 30.232 1.00 110.16 ? 1454 MAN B O5 1 HETATM 10049 O O6 . MAN FA 12 . ? 45.306 15.315 29.978 1.00 108.65 ? 1454 MAN B O6 1 HETATM 10050 C C1 . NAG GA 9 . ? 41.238 17.362 26.041 1.00 107.52 ? 1455 NAG B C1 1 HETATM 10051 C C2 . NAG GA 9 . ? 41.826 16.800 24.748 1.00 107.58 ? 1455 NAG B C2 1 HETATM 10052 C C3 . NAG GA 9 . ? 41.361 17.667 23.586 1.00 107.03 ? 1455 NAG B C3 1 HETATM 10053 C C4 . NAG GA 9 . ? 39.837 17.586 23.539 1.00 106.98 ? 1455 NAG B C4 1 HETATM 10054 C C5 . NAG GA 9 . ? 39.278 18.132 24.854 1.00 106.49 ? 1455 NAG B C5 1 HETATM 10055 C C6 . NAG GA 9 . ? 37.766 18.035 24.912 1.00 106.91 ? 1455 NAG B C6 1 HETATM 10056 C C7 . NAG GA 9 . ? 43.923 15.739 24.243 1.00 109.17 ? 1455 NAG B C7 1 HETATM 10057 C C8 . NAG GA 9 . ? 44.553 15.979 22.876 1.00 108.34 ? 1455 NAG B C8 1 HETATM 10058 N N2 . NAG GA 9 . ? 43.273 16.754 24.807 1.00 108.50 ? 1455 NAG B N2 1 HETATM 10059 O O3 . NAG GA 9 . ? 41.926 17.196 22.374 1.00 106.18 ? 1455 NAG B O3 1 HETATM 10060 O O4 . NAG GA 9 . ? 39.310 18.327 22.418 1.00 107.59 ? 1455 NAG B O4 1 HETATM 10061 O O5 . NAG GA 9 . ? 39.797 17.367 25.971 1.00 107.16 ? 1455 NAG B O5 1 HETATM 10062 O O6 . NAG GA 9 . ? 37.327 16.702 24.695 1.00 106.64 ? 1455 NAG B O6 1 HETATM 10063 O O7 . NAG GA 9 . ? 44.020 14.632 24.776 1.00 108.98 ? 1455 NAG B O7 1 HETATM 10064 C C1 . GAL HA 14 . ? 39.576 17.833 21.143 1.00 108.81 ? 1456 GAL B C1 1 HETATM 10065 C C2 . GAL HA 14 . ? 38.895 16.469 20.923 1.00 108.98 ? 1456 GAL B C2 1 HETATM 10066 C C3 . GAL HA 14 . ? 39.196 15.990 19.503 1.00 108.90 ? 1456 GAL B C3 1 HETATM 10067 C C4 . GAL HA 14 . ? 38.769 17.053 18.485 1.00 108.63 ? 1456 GAL B C4 1 HETATM 10068 C C5 . GAL HA 14 . ? 39.399 18.409 18.821 1.00 109.02 ? 1456 GAL B C5 1 HETATM 10069 C C6 . GAL HA 14 . ? 38.880 19.522 17.928 1.00 109.13 ? 1456 GAL B C6 1 HETATM 10070 O O2 . GAL HA 14 . ? 39.371 15.513 21.863 1.00 108.66 ? 1456 GAL B O2 1 HETATM 10071 O O3 . GAL HA 14 . ? 38.506 14.773 19.254 1.00 108.85 ? 1456 GAL B O3 1 HETATM 10072 O O4 . GAL HA 14 . ? 37.358 17.178 18.496 1.00 110.31 ? 1456 GAL B O4 1 HETATM 10073 O O5 . GAL HA 14 . ? 39.085 18.781 20.183 1.00 109.40 ? 1456 GAL B O5 1 HETATM 10074 O O6 . GAL HA 14 . ? 39.645 19.630 16.734 1.00 109.71 ? 1456 GAL B O6 1 HETATM 10075 C C1 . BMA IA 11 . ? 45.217 23.538 34.124 1.00 118.41 ? 1457 BMA B C1 1 HETATM 10076 C C2 . BMA IA 11 . ? 46.342 24.556 34.371 1.00 118.22 ? 1457 BMA B C2 1 HETATM 10077 C C3 . BMA IA 11 . ? 46.029 25.474 35.571 1.00 117.51 ? 1457 BMA B C3 1 HETATM 10078 C C4 . BMA IA 11 . ? 44.576 25.987 35.571 1.00 117.02 ? 1457 BMA B C4 1 HETATM 10079 C C5 . BMA IA 11 . ? 43.587 24.855 35.294 1.00 116.58 ? 1457 BMA B C5 1 HETATM 10080 C C6 . BMA IA 11 . ? 42.155 25.345 35.152 1.00 115.32 ? 1457 BMA B C6 1 HETATM 10081 O O2 . BMA IA 11 . ? 46.643 25.306 33.162 1.00 119.50 ? 1457 BMA B O2 1 HETATM 10082 O O3 . BMA IA 11 . ? 46.921 26.578 35.566 1.00 118.08 ? 1457 BMA B O3 1 HETATM 10083 O O4 . BMA IA 11 . ? 44.276 26.573 36.828 1.00 117.59 ? 1457 BMA B O4 1 HETATM 10084 O O5 . BMA IA 11 . ? 43.948 24.187 34.070 1.00 117.79 ? 1457 BMA B O5 1 HETATM 10085 O O6 . BMA IA 11 . ? 41.620 25.038 33.876 1.00 112.13 ? 1457 BMA B O6 1 HETATM 10086 C C1 . NAG JA 9 . ? 46.229 26.627 32.993 1.00 121.08 ? 1458 NAG B C1 1 HETATM 10087 C C2 . NAG JA 9 . ? 46.877 27.207 31.724 1.00 121.31 ? 1458 NAG B C2 1 HETATM 10088 C C3 . NAG JA 9 . ? 46.329 28.609 31.434 1.00 121.08 ? 1458 NAG B C3 1 HETATM 10089 C C4 . NAG JA 9 . ? 44.795 28.601 31.424 1.00 121.40 ? 1458 NAG B C4 1 HETATM 10090 C C5 . NAG JA 9 . ? 44.272 27.980 32.718 1.00 121.17 ? 1458 NAG B C5 1 HETATM 10091 C C6 . NAG JA 9 . ? 42.758 27.880 32.748 1.00 120.57 ? 1458 NAG B C6 1 HETATM 10092 C C7 . NAG JA 9 . ? 49.097 26.326 31.358 1.00 122.75 ? 1458 NAG B C7 1 HETATM 10093 C C8 . NAG JA 9 . ? 49.515 25.173 32.263 1.00 122.45 ? 1458 NAG B C8 1 HETATM 10094 N N2 . NAG JA 9 . ? 48.319 27.269 31.885 1.00 122.42 ? 1458 NAG B N2 1 HETATM 10095 O O3 . NAG JA 9 . ? 46.811 29.056 30.175 1.00 120.62 ? 1458 NAG B O3 1 HETATM 10096 O O4 . NAG JA 9 . ? 44.303 29.927 31.300 1.00 121.86 ? 1458 NAG B O4 1 HETATM 10097 O O5 . NAG JA 9 . ? 44.798 26.642 32.863 1.00 121.71 ? 1458 NAG B O5 1 HETATM 10098 O O6 . NAG JA 9 . ? 42.195 28.863 33.604 1.00 119.75 ? 1458 NAG B O6 1 HETATM 10099 O O7 . NAG JA 9 . ? 49.485 26.359 30.189 1.00 122.57 ? 1458 NAG B O7 1 HETATM 10100 C C . ACT KA 8 . ? 86.060 -22.116 23.062 1.00 81.57 ? 1215 ACT H C 1 HETATM 10101 O O . ACT KA 8 . ? 86.052 -21.827 24.347 1.00 81.57 ? 1215 ACT H O 1 HETATM 10102 O OXT . ACT KA 8 . ? 86.725 -21.509 22.156 1.00 81.57 ? 1215 ACT H OXT 1 HETATM 10103 C CH3 . ACT KA 8 . ? 85.242 -23.246 22.510 1.00 81.57 ? 1215 ACT H CH3 1 HETATM 10104 C C1 . MPD LA 7 . ? 90.225 23.028 -15.989 1.00 81.57 ? 1212 MPD M C1 1 HETATM 10105 C C2 . MPD LA 7 . ? 91.180 24.192 -15.925 1.00 81.57 ? 1212 MPD M C2 1 HETATM 10106 O O2 . MPD LA 7 . ? 92.123 23.888 -14.886 1.00 81.57 ? 1212 MPD M O2 1 HETATM 10107 C CM . MPD LA 7 . ? 91.892 24.375 -17.228 1.00 81.57 ? 1212 MPD M CM 1 HETATM 10108 C C3 . MPD LA 7 . ? 90.489 25.538 -15.561 1.00 81.57 ? 1212 MPD M C3 1 HETATM 10109 C C4 . MPD LA 7 . ? 90.363 25.894 -14.075 1.00 81.57 ? 1212 MPD M C4 1 HETATM 10110 O O4 . MPD LA 7 . ? 91.635 25.985 -13.415 1.00 81.57 ? 1212 MPD M O4 1 HETATM 10111 C C5 . MPD LA 7 . ? 89.672 27.226 -13.870 1.00 81.57 ? 1212 MPD M C5 1 HETATM 10112 O O . HOH MA 15 . ? 48.311 19.622 46.449 1.00 40.32 ? 2001 HOH A O 1 HETATM 10113 O O . HOH MA 15 . ? 69.518 13.139 52.001 1.00 32.60 ? 2002 HOH A O 1 HETATM 10114 O O . HOH MA 15 . ? 42.277 33.070 55.323 1.00 37.01 ? 2003 HOH A O 1 HETATM 10115 O O . HOH MA 15 . ? 36.127 35.149 59.480 1.00 45.40 ? 2004 HOH A O 1 HETATM 10116 O O . HOH MA 15 . ? 51.979 24.878 62.780 1.00 48.78 ? 2005 HOH A O 1 HETATM 10117 O O . HOH MA 15 . ? 62.741 21.002 57.379 1.00 58.94 ? 2006 HOH A O 1 HETATM 10118 O O . HOH MA 15 . ? 50.147 39.774 60.070 1.00 27.84 ? 2007 HOH A O 1 HETATM 10119 O O . HOH MA 15 . ? 47.427 40.497 58.339 1.00 23.20 ? 2008 HOH A O 1 HETATM 10120 O O . HOH MA 15 . ? 68.928 12.556 48.995 1.00 51.78 ? 2009 HOH A O 1 HETATM 10121 O O . HOH MA 15 . ? 57.576 8.785 48.632 1.00 32.41 ? 2010 HOH A O 1 HETATM 10122 O O . HOH MA 15 . ? 48.886 16.640 46.087 1.00 39.16 ? 2011 HOH A O 1 HETATM 10123 O O . HOH MA 15 . ? 55.667 -0.113 36.233 1.00 51.81 ? 2012 HOH A O 1 HETATM 10124 O O . HOH MA 15 . ? 77.090 14.627 11.664 1.00 49.27 ? 2013 HOH A O 1 HETATM 10125 O O . HOH MA 15 . ? 70.633 16.861 13.540 1.00 37.48 ? 2014 HOH A O 1 HETATM 10126 O O . HOH MA 15 . ? 70.668 24.180 13.568 1.00 37.61 ? 2015 HOH A O 1 HETATM 10127 O O . HOH MA 15 . ? 70.764 15.333 16.599 1.00 38.89 ? 2016 HOH A O 1 HETATM 10128 O O . HOH MA 15 . ? 62.151 3.092 21.720 1.00 21.35 ? 2017 HOH A O 1 HETATM 10129 O O . HOH MA 15 . ? 65.494 -0.271 23.195 1.00 37.28 ? 2018 HOH A O 1 HETATM 10130 O O . HOH MA 15 . ? 55.367 9.194 37.241 1.00 46.57 ? 2019 HOH A O 1 HETATM 10131 O O . HOH MA 15 . ? 69.016 27.353 27.555 1.00 42.43 ? 2020 HOH A O 1 HETATM 10132 O O . HOH MA 15 . ? 70.779 25.718 29.909 1.00 41.74 ? 2021 HOH A O 1 HETATM 10133 O O . HOH MA 15 . ? 55.581 13.186 31.545 1.00 28.80 ? 2022 HOH A O 1 HETATM 10134 O O . HOH MA 15 . ? 60.701 3.454 27.161 1.00 61.76 ? 2023 HOH A O 1 HETATM 10135 O O . HOH MA 15 . ? 84.903 23.663 23.572 1.00 60.04 ? 2024 HOH A O 1 HETATM 10136 O O . HOH MA 15 . ? 87.210 19.150 9.928 1.00 57.38 ? 2025 HOH A O 1 HETATM 10137 O O . HOH MA 15 . ? 62.933 2.063 45.039 1.00 44.35 ? 2026 HOH A O 1 HETATM 10138 O O . HOH MA 15 . ? 64.409 8.810 39.928 1.00 38.27 ? 2027 HOH A O 1 HETATM 10139 O O . HOH MA 15 . ? 73.694 3.485 35.916 1.00 44.28 ? 2028 HOH A O 1 HETATM 10140 O O . HOH MA 15 . ? 52.224 33.904 63.622 1.00 41.80 ? 2029 HOH A O 1 HETATM 10141 O O . HOH MA 15 . ? 53.602 35.316 40.156 1.00 43.53 ? 2030 HOH A O 1 HETATM 10142 O O . HOH MA 15 . ? 51.104 31.795 39.644 1.00 48.75 ? 2031 HOH A O 1 HETATM 10143 O O . HOH MA 15 . ? 57.545 22.895 40.193 1.00 48.11 ? 2032 HOH A O 1 HETATM 10144 O O . HOH NA 15 . ? 57.298 37.638 16.441 1.00 45.14 ? 2001 HOH B O 1 HETATM 10145 O O . HOH NA 15 . ? 68.182 14.149 9.314 1.00 60.52 ? 2002 HOH B O 1 HETATM 10146 O O . HOH NA 15 . ? 74.892 6.025 22.183 1.00 26.98 ? 2003 HOH B O 1 HETATM 10147 O O . HOH NA 15 . ? 67.658 6.769 16.950 1.00 25.44 ? 2004 HOH B O 1 HETATM 10148 O O . HOH NA 15 . ? 52.834 28.271 20.372 1.00 47.53 ? 2005 HOH B O 1 HETATM 10149 O O . HOH NA 15 . ? 48.004 26.841 14.035 1.00 35.74 ? 2006 HOH B O 1 HETATM 10150 O O . HOH NA 15 . ? 52.484 12.800 16.812 1.00 32.01 ? 2007 HOH B O 1 HETATM 10151 O O . HOH NA 15 . ? 54.056 9.455 2.233 1.00 36.64 ? 2008 HOH B O 1 HETATM 10152 O O . HOH NA 15 . ? 49.800 -2.937 8.453 1.00 51.11 ? 2009 HOH B O 1 HETATM 10153 O O . HOH NA 15 . ? 59.554 24.993 27.166 1.00 36.52 ? 2010 HOH B O 1 HETATM 10154 O O . HOH NA 15 . ? 58.487 32.138 22.023 1.00 46.43 ? 2011 HOH B O 1 HETATM 10155 O O . HOH NA 15 . ? 58.420 -3.059 13.908 1.00 42.01 ? 2012 HOH B O 1 HETATM 10156 O O . HOH NA 15 . ? 63.593 -8.104 14.957 1.00 45.19 ? 2013 HOH B O 1 HETATM 10157 O O . HOH NA 15 . ? 66.370 0.557 7.036 1.00 31.33 ? 2014 HOH B O 1 HETATM 10158 O O . HOH NA 15 . ? 50.546 25.252 11.904 1.00 47.21 ? 2015 HOH B O 1 HETATM 10159 O O . HOH NA 15 . ? 70.172 -1.540 2.825 1.00 52.65 ? 2016 HOH B O 1 HETATM 10160 O O . HOH OA 15 . ? 97.124 -3.290 32.372 1.00 59.35 ? 2001 HOH H O 1 HETATM 10161 O O . HOH OA 15 . ? 93.650 -25.384 24.794 1.00 54.47 ? 2002 HOH H O 1 HETATM 10162 O O . HOH OA 15 . ? 78.801 -18.060 23.642 1.00 33.84 ? 2003 HOH H O 1 HETATM 10163 O O . HOH OA 15 . ? 78.999 -10.336 37.351 1.00 48.19 ? 2004 HOH H O 1 HETATM 10164 O O . HOH OA 15 . ? 81.181 -6.639 36.573 1.00 45.51 ? 2005 HOH H O 1 HETATM 10165 O O . HOH OA 15 . ? 83.067 0.151 20.776 1.00 53.79 ? 2006 HOH H O 1 HETATM 10166 O O . HOH OA 15 . ? 80.769 9.239 20.355 1.00 36.89 ? 2007 HOH H O 1 HETATM 10167 O O . HOH OA 15 . ? 74.575 -5.372 15.436 1.00 27.33 ? 2008 HOH H O 1 HETATM 10168 O O . HOH OA 15 . ? 76.184 -3.916 17.810 1.00 39.27 ? 2009 HOH H O 1 HETATM 10169 O O . HOH PA 15 . ? 77.811 5.600 -12.149 1.00 42.35 ? 2001 HOH I O 1 HETATM 10170 O O . HOH PA 15 . ? 67.357 26.454 -30.339 1.00 33.24 ? 2002 HOH I O 1 HETATM 10171 O O . HOH PA 15 . ? 69.688 37.005 -23.186 1.00 42.26 ? 2003 HOH I O 1 HETATM 10172 O O . HOH PA 15 . ? 66.231 1.028 -11.668 1.00 35.41 ? 2004 HOH I O 1 HETATM 10173 O O . HOH PA 15 . ? 70.807 4.477 -0.688 1.00 50.79 ? 2005 HOH I O 1 HETATM 10174 O O . HOH PA 15 . ? 83.457 27.808 -8.220 1.00 34.45 ? 2006 HOH I O 1 HETATM 10175 O O . HOH PA 15 . ? 65.486 12.462 -1.562 1.00 40.30 ? 2007 HOH I O 1 HETATM 10176 O O . HOH PA 15 . ? 79.534 30.136 -5.990 1.00 22.98 ? 2008 HOH I O 1 HETATM 10177 O O . HOH PA 15 . ? 65.782 30.392 -5.746 1.00 50.52 ? 2009 HOH I O 1 HETATM 10178 O O . HOH PA 15 . ? 57.993 14.514 -14.584 1.00 30.35 ? 2010 HOH I O 1 HETATM 10179 O O . HOH PA 15 . ? 55.953 8.787 -18.186 1.00 45.22 ? 2011 HOH I O 1 HETATM 10180 O O . HOH PA 15 . ? 81.036 29.551 -20.863 1.00 50.08 ? 2012 HOH I O 1 HETATM 10181 O O . HOH PA 15 . ? 70.030 6.176 -3.259 1.00 24.01 ? 2013 HOH I O 1 HETATM 10182 O O . HOH PA 15 . ? 73.227 13.650 0.024 1.00 35.52 ? 2014 HOH I O 1 HETATM 10183 O O . HOH PA 15 . ? 76.734 18.778 4.202 1.00 37.75 ? 2015 HOH I O 1 HETATM 10184 O O . HOH PA 15 . ? 76.168 7.847 -13.431 1.00 34.93 ? 2016 HOH I O 1 HETATM 10185 O O . HOH PA 15 . ? 75.186 17.827 -26.425 1.00 41.24 ? 2017 HOH I O 1 HETATM 10186 O O . HOH PA 15 . ? 86.653 4.982 -46.027 1.00 58.00 ? 2018 HOH I O 1 HETATM 10187 O O . HOH PA 15 . ? 104.373 16.670 -38.510 1.00 55.32 ? 2019 HOH I O 1 HETATM 10188 O O . HOH PA 15 . ? 97.295 19.481 -55.636 1.00 45.48 ? 2020 HOH I O 1 HETATM 10189 O O . HOH QA 15 . ? 97.705 -19.080 15.988 1.00 58.18 ? 2001 HOH L O 1 HETATM 10190 O O . HOH QA 15 . ? 76.986 -7.060 1.876 1.00 36.90 ? 2002 HOH L O 1 HETATM 10191 O O . HOH QA 15 . ? 70.481 -11.378 -1.361 1.00 49.34 ? 2003 HOH L O 1 HETATM 10192 O O . HOH QA 15 . ? 117.908 -38.510 39.434 1.00 62.28 ? 2004 HOH L O 1 HETATM 10193 O O . HOH RA 15 . ? 105.304 5.020 -10.714 1.00 34.21 ? 2001 HOH M O 1 HETATM 10194 O O . HOH RA 15 . ? 101.201 22.318 -4.446 1.00 65.94 ? 2002 HOH M O 1 HETATM 10195 O O . HOH RA 15 . ? 88.185 17.760 -19.373 1.00 48.24 ? 2003 HOH M O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 216 ? ? ? A . n A 1 2 PRO 2 217 ? ? ? A . n A 1 3 LYS 3 218 ? ? ? A . n A 1 4 SER 4 219 ? ? ? A . n A 1 5 CYS 5 220 ? ? ? A . n A 1 6 ASP 6 221 ? ? ? A . n A 1 7 LYS 7 222 ? ? ? A . n A 1 8 THR 8 223 ? ? ? A . n A 1 9 HIS 9 224 ? ? ? A . n A 1 10 THR 10 225 ? ? ? A . n A 1 11 CYS 11 226 ? ? ? A . n A 1 12 PRO 12 227 ? ? ? A . n A 1 13 PRO 13 228 ? ? ? A . n A 1 14 CYS 14 229 ? ? ? A . n A 1 15 PRO 15 230 ? ? ? A . n A 1 16 ALA 16 231 ? ? ? A . n A 1 17 PRO 17 232 ? ? ? A . n A 1 18 GLU 18 233 ? ? ? A . n A 1 19 LEU 19 234 ? ? ? A . n A 1 20 LEU 20 235 ? ? ? A . n A 1 21 GLY 21 236 236 GLY GLY A . n A 1 22 GLY 22 237 237 GLY GLY A . n A 1 23 PRO 23 238 238 PRO PRO A . n A 1 24 SER 24 239 239 SER SER A . n A 1 25 VAL 25 240 240 VAL VAL A . n A 1 26 PHE 26 241 241 PHE PHE A . n A 1 27 LEU 27 242 242 LEU LEU A . n A 1 28 PHE 28 243 243 PHE PHE A . n A 1 29 PRO 29 244 244 PRO PRO A . n A 1 30 PRO 30 245 245 PRO PRO A . n A 1 31 LYS 31 246 246 LYS LYS A . n A 1 32 PRO 32 247 247 PRO PRO A . n A 1 33 LYS 33 248 248 LYS LYS A . n A 1 34 ASP 34 249 249 ASP ASP A . n A 1 35 THR 35 250 250 THR THR A . n A 1 36 LEU 36 251 251 LEU LEU A . n A 1 37 MET 37 252 252 MET MET A . n A 1 38 ILE 38 253 253 ILE ILE A . n A 1 39 SER 39 254 254 SER SER A . n A 1 40 ARG 40 255 255 ARG ARG A . n A 1 41 THR 41 256 256 THR THR A . n A 1 42 PRO 42 257 257 PRO PRO A . n A 1 43 GLU 43 258 258 GLU GLU A . n A 1 44 VAL 44 259 259 VAL VAL A . n A 1 45 THR 45 260 260 THR THR A . n A 1 46 CYS 46 261 261 CYS CYS A . n A 1 47 VAL 47 262 262 VAL VAL A . n A 1 48 VAL 48 263 263 VAL VAL A . n A 1 49 VAL 49 264 264 VAL VAL A . n A 1 50 ASP 50 265 265 ASP ASP A . n A 1 51 VAL 51 266 266 VAL VAL A . n A 1 52 SER 52 267 267 SER SER A . n A 1 53 HIS 53 268 268 HIS HIS A . n A 1 54 GLU 54 269 269 GLU GLU A . n A 1 55 GLU 55 270 270 GLU GLU A . n A 1 56 PRO 56 271 271 PRO PRO A . n A 1 57 GLU 57 272 272 GLU GLU A . n A 1 58 VAL 58 273 273 VAL VAL A . n A 1 59 LYS 59 274 274 LYS LYS A . n A 1 60 PHE 60 275 275 PHE PHE A . n A 1 61 ASN 61 276 276 ASN ASN A . n A 1 62 TRP 62 277 277 TRP TRP A . n A 1 63 TYR 63 278 278 TYR TYR A . n A 1 64 VAL 64 279 279 VAL VAL A . n A 1 65 ASP 65 280 280 ASP ASP A . n A 1 66 GLY 66 281 281 GLY GLY A . n A 1 67 VAL 67 282 282 VAL VAL A . n A 1 68 GLU 68 283 283 GLU GLU A . n A 1 69 VAL 69 284 284 VAL VAL A . n A 1 70 HIS 70 285 285 HIS HIS A . n A 1 71 ASN 71 286 286 ASN ASN A . n A 1 72 ALA 72 287 287 ALA ALA A . n A 1 73 LYS 73 288 288 LYS LYS A . n A 1 74 THR 74 289 289 THR THR A . n A 1 75 LYS 75 290 290 LYS LYS A . n A 1 76 PRO 76 291 291 PRO PRO A . n A 1 77 ARG 77 292 292 ARG ARG A . n A 1 78 GLU 78 293 293 GLU GLU A . n A 1 79 GLU 79 294 294 GLU GLU A . n A 1 80 GLN 80 295 295 GLN GLN A . n A 1 81 TYR 81 296 296 TYR TYR A . n A 1 82 ASN 82 297 297 ASN ASN A . n A 1 83 SER 83 298 298 SER SER A . n A 1 84 THR 84 299 299 THR THR A . n A 1 85 TYR 85 300 300 TYR TYR A . n A 1 86 ARG 86 301 301 ARG ARG A . n A 1 87 VAL 87 302 302 VAL VAL A . n A 1 88 VAL 88 303 303 VAL VAL A . n A 1 89 SER 89 304 304 SER SER A . n A 1 90 VAL 90 305 305 VAL VAL A . n A 1 91 LEU 91 306 306 LEU LEU A . n A 1 92 THR 92 307 307 THR THR A . n A 1 93 VAL 93 308 308 VAL VAL A . n A 1 94 LEU 94 309 309 LEU LEU A . n A 1 95 HIS 95 310 310 HIS HIS A . n A 1 96 GLN 96 311 311 GLN GLN A . n A 1 97 ASP 97 312 312 ASP ASP A . n A 1 98 TRP 98 313 313 TRP TRP A . n A 1 99 LEU 99 314 314 LEU LEU A . n A 1 100 ASN 100 315 315 ASN ASN A . n A 1 101 GLY 101 316 316 GLY GLY A . n A 1 102 LYS 102 317 317 LYS LYS A . n A 1 103 GLU 103 318 318 GLU GLU A . n A 1 104 TYR 104 319 319 TYR TYR A . n A 1 105 LYS 105 320 320 LYS LYS A . n A 1 106 CYS 106 321 321 CYS CYS A . n A 1 107 LYS 107 322 322 LYS LYS A . n A 1 108 VAL 108 323 323 VAL VAL A . n A 1 109 SER 109 324 324 SER SER A . n A 1 110 ASN 110 325 325 ASN ASN A . n A 1 111 LYS 111 326 326 LYS LYS A . n A 1 112 ALA 112 327 327 ALA ALA A . n A 1 113 LEU 113 328 328 LEU LEU A . n A 1 114 PRO 114 329 329 PRO PRO A . n A 1 115 ALA 115 330 330 ALA ALA A . n A 1 116 PRO 116 331 331 PRO PRO A . n A 1 117 ILE 117 332 332 ILE ILE A . n A 1 118 GLU 118 333 333 GLU GLU A . n A 1 119 LYS 119 334 334 LYS LYS A . n A 1 120 THR 120 335 335 THR THR A . n A 1 121 ILE 121 336 336 ILE ILE A . n A 1 122 SER 122 337 337 SER SER A . n A 1 123 LYS 123 338 338 LYS LYS A . n A 1 124 ALA 124 339 339 ALA ALA A . n A 1 125 LYS 125 340 340 LYS LYS A . n A 1 126 GLY 126 341 341 GLY GLY A . n A 1 127 GLN 127 342 342 GLN GLN A . n A 1 128 PRO 128 343 343 PRO PRO A . n A 1 129 ARG 129 344 344 ARG ARG A . n A 1 130 GLU 130 345 345 GLU GLU A . n A 1 131 PRO 131 346 346 PRO PRO A . n A 1 132 GLN 132 347 347 GLN GLN A . n A 1 133 VAL 133 348 348 VAL VAL A . n A 1 134 TYR 134 349 349 TYR TYR A . n A 1 135 THR 135 350 350 THR THR A . n A 1 136 LEU 136 351 351 LEU LEU A . n A 1 137 PRO 137 352 352 PRO PRO A . n A 1 138 PRO 138 353 353 PRO PRO A . n A 1 139 SER 139 354 354 SER SER A . n A 1 140 ARG 140 355 355 ARG ARG A . n A 1 141 ASP 141 356 356 ASP ASP A . n A 1 142 GLU 142 357 357 GLU GLU A . n A 1 143 LEU 143 358 358 LEU LEU A . n A 1 144 THR 144 359 359 THR THR A . n A 1 145 LYS 145 360 360 LYS LYS A . n A 1 146 ASN 146 361 361 ASN ASN A . n A 1 147 GLN 147 362 362 GLN GLN A . n A 1 148 VAL 148 363 363 VAL VAL A . n A 1 149 SER 149 364 364 SER SER A . n A 1 150 LEU 150 365 365 LEU LEU A . n A 1 151 THR 151 366 366 THR THR A . n A 1 152 CYS 152 367 367 CYS CYS A . n A 1 153 LEU 153 368 368 LEU LEU A . n A 1 154 VAL 154 369 369 VAL VAL A . n A 1 155 LYS 155 370 370 LYS LYS A . n A 1 156 GLY 156 371 371 GLY GLY A . n A 1 157 PHE 157 372 372 PHE PHE A . n A 1 158 TYR 158 373 373 TYR TYR A . n A 1 159 PRO 159 374 374 PRO PRO A . n A 1 160 SER 160 375 375 SER SER A . n A 1 161 ASP 161 376 376 ASP ASP A . n A 1 162 ILE 162 377 377 ILE ILE A . n A 1 163 ALA 163 378 378 ALA ALA A . n A 1 164 VAL 164 379 379 VAL VAL A . n A 1 165 GLU 165 380 380 GLU GLU A . n A 1 166 TRP 166 381 381 TRP TRP A . n A 1 167 GLU 167 382 382 GLU GLU A . n A 1 168 SER 168 383 383 SER SER A . n A 1 169 ASN 169 384 384 ASN ASN A . n A 1 170 GLY 170 385 385 GLY GLY A . n A 1 171 GLN 171 386 386 GLN GLN A . n A 1 172 PRO 172 387 387 PRO PRO A . n A 1 173 GLU 173 388 388 GLU GLU A . n A 1 174 ASN 174 389 389 ASN ASN A . n A 1 175 ASN 175 390 390 ASN ASN A . n A 1 176 TYR 176 391 391 TYR TYR A . n A 1 177 LYS 177 392 392 LYS LYS A . n A 1 178 THR 178 393 393 THR THR A . n A 1 179 THR 179 394 394 THR THR A . n A 1 180 PRO 180 395 395 PRO PRO A . n A 1 181 PRO 181 396 396 PRO PRO A . n A 1 182 VAL 182 397 397 VAL VAL A . n A 1 183 LEU 183 398 398 LEU LEU A . n A 1 184 ASP 184 399 399 ASP ASP A . n A 1 185 SER 185 400 400 SER SER A . n A 1 186 ASP 186 401 401 ASP ASP A . n A 1 187 GLY 187 402 402 GLY GLY A . n A 1 188 SER 188 403 403 SER SER A . n A 1 189 PHE 189 404 404 PHE PHE A . n A 1 190 PHE 190 405 405 PHE PHE A . n A 1 191 LEU 191 406 406 LEU LEU A . n A 1 192 TYR 192 407 407 TYR TYR A . n A 1 193 SER 193 408 408 SER SER A . n A 1 194 LYS 194 409 409 LYS LYS A . n A 1 195 LEU 195 410 410 LEU LEU A . n A 1 196 THR 196 411 411 THR THR A . n A 1 197 VAL 197 412 412 VAL VAL A . n A 1 198 ASP 198 413 413 ASP ASP A . n A 1 199 LYS 199 414 414 LYS LYS A . n A 1 200 SER 200 415 415 SER SER A . n A 1 201 ARG 201 416 416 ARG ARG A . n A 1 202 TRP 202 417 417 TRP TRP A . n A 1 203 GLN 203 418 418 GLN GLN A . n A 1 204 GLN 204 419 419 GLN GLN A . n A 1 205 GLY 205 420 420 GLY GLY A . n A 1 206 ASN 206 421 421 ASN ASN A . n A 1 207 VAL 207 422 422 VAL VAL A . n A 1 208 PHE 208 423 423 PHE PHE A . n A 1 209 SER 209 424 424 SER SER A . n A 1 210 CYS 210 425 425 CYS CYS A . n A 1 211 SER 211 426 426 SER SER A . n A 1 212 VAL 212 427 427 VAL VAL A . n A 1 213 MET 213 428 428 MET MET A . n A 1 214 HIS 214 429 429 HIS HIS A . n A 1 215 GLU 215 430 430 GLU GLU A . n A 1 216 ALA 216 431 431 ALA ALA A . n A 1 217 LEU 217 432 432 LEU LEU A . n A 1 218 HIS 218 433 433 HIS HIS A . n A 1 219 ASN 219 434 434 ASN ASN A . n A 1 220 HIS 220 435 435 HIS HIS A . n A 1 221 TYR 221 436 436 TYR TYR A . n A 1 222 THR 222 437 437 THR THR A . n A 1 223 GLN 223 438 438 GLN GLN A . n A 1 224 LYS 224 439 439 LYS LYS A . n A 1 225 SER 225 440 440 SER SER A . n A 1 226 LEU 226 441 441 LEU LEU A . n A 1 227 SER 227 442 442 SER SER A . n A 1 228 LEU 228 443 443 LEU LEU A . n A 1 229 SER 229 444 444 SER SER A . n A 1 230 PRO 230 445 445 PRO PRO A . n A 1 231 GLY 231 446 ? ? ? A . n A 1 232 LYS 232 447 ? ? ? A . n B 1 1 GLU 1 216 ? ? ? B . n B 1 2 PRO 2 217 ? ? ? B . n B 1 3 LYS 3 218 ? ? ? B . n B 1 4 SER 4 219 ? ? ? B . n B 1 5 CYS 5 220 ? ? ? B . n B 1 6 ASP 6 221 ? ? ? B . n B 1 7 LYS 7 222 ? ? ? B . n B 1 8 THR 8 223 ? ? ? B . n B 1 9 HIS 9 224 ? ? ? B . n B 1 10 THR 10 225 ? ? ? B . n B 1 11 CYS 11 226 ? ? ? B . n B 1 12 PRO 12 227 ? ? ? B . n B 1 13 PRO 13 228 ? ? ? B . n B 1 14 CYS 14 229 ? ? ? B . n B 1 15 PRO 15 230 ? ? ? B . n B 1 16 ALA 16 231 ? ? ? B . n B 1 17 PRO 17 232 ? ? ? B . n B 1 18 GLU 18 233 ? ? ? B . n B 1 19 LEU 19 234 ? ? ? B . n B 1 20 LEU 20 235 ? ? ? B . n B 1 21 GLY 21 236 ? ? ? B . n B 1 22 GLY 22 237 ? ? ? B . n B 1 23 PRO 23 238 238 PRO PRO B . n B 1 24 SER 24 239 239 SER SER B . n B 1 25 VAL 25 240 240 VAL VAL B . n B 1 26 PHE 26 241 241 PHE PHE B . n B 1 27 LEU 27 242 242 LEU LEU B . n B 1 28 PHE 28 243 243 PHE PHE B . n B 1 29 PRO 29 244 244 PRO PRO B . n B 1 30 PRO 30 245 245 PRO PRO B . n B 1 31 LYS 31 246 246 LYS LYS B . n B 1 32 PRO 32 247 247 PRO PRO B . n B 1 33 LYS 33 248 248 LYS LYS B . n B 1 34 ASP 34 249 249 ASP ASP B . n B 1 35 THR 35 250 250 THR THR B . n B 1 36 LEU 36 251 251 LEU LEU B . n B 1 37 MET 37 252 252 MET MET B . n B 1 38 ILE 38 253 253 ILE ILE B . n B 1 39 SER 39 254 254 SER SER B . n B 1 40 ARG 40 255 255 ARG ARG B . n B 1 41 THR 41 256 256 THR THR B . n B 1 42 PRO 42 257 257 PRO PRO B . n B 1 43 GLU 43 258 258 GLU GLU B . n B 1 44 VAL 44 259 259 VAL VAL B . n B 1 45 THR 45 260 260 THR THR B . n B 1 46 CYS 46 261 261 CYS CYS B . n B 1 47 VAL 47 262 262 VAL VAL B . n B 1 48 VAL 48 263 263 VAL VAL B . n B 1 49 VAL 49 264 264 VAL VAL B . n B 1 50 ASP 50 265 265 ASP ASP B . n B 1 51 VAL 51 266 266 VAL VAL B . n B 1 52 SER 52 267 267 SER SER B . n B 1 53 HIS 53 268 268 HIS HIS B . n B 1 54 GLU 54 269 269 GLU GLU B . n B 1 55 GLU 55 270 270 GLU GLU B . n B 1 56 PRO 56 271 271 PRO PRO B . n B 1 57 GLU 57 272 272 GLU GLU B . n B 1 58 VAL 58 273 273 VAL VAL B . n B 1 59 LYS 59 274 274 LYS LYS B . n B 1 60 PHE 60 275 275 PHE PHE B . n B 1 61 ASN 61 276 276 ASN ASN B . n B 1 62 TRP 62 277 277 TRP TRP B . n B 1 63 TYR 63 278 278 TYR TYR B . n B 1 64 VAL 64 279 279 VAL VAL B . n B 1 65 ASP 65 280 280 ASP ASP B . n B 1 66 GLY 66 281 281 GLY GLY B . n B 1 67 VAL 67 282 282 VAL VAL B . n B 1 68 GLU 68 283 283 GLU GLU B . n B 1 69 VAL 69 284 284 VAL VAL B . n B 1 70 HIS 70 285 285 HIS HIS B . n B 1 71 ASN 71 286 286 ASN ASN B . n B 1 72 ALA 72 287 287 ALA ALA B . n B 1 73 LYS 73 288 288 LYS LYS B . n B 1 74 THR 74 289 289 THR THR B . n B 1 75 LYS 75 290 290 LYS LYS B . n B 1 76 PRO 76 291 291 PRO PRO B . n B 1 77 ARG 77 292 292 ARG ARG B . n B 1 78 GLU 78 293 293 GLU GLU B . n B 1 79 GLU 79 294 294 GLU GLU B . n B 1 80 GLN 80 295 295 GLN GLN B . n B 1 81 TYR 81 296 296 TYR TYR B . n B 1 82 ASN 82 297 297 ASN ASN B . n B 1 83 SER 83 298 298 SER SER B . n B 1 84 THR 84 299 299 THR THR B . n B 1 85 TYR 85 300 300 TYR TYR B . n B 1 86 ARG 86 301 301 ARG ARG B . n B 1 87 VAL 87 302 302 VAL VAL B . n B 1 88 VAL 88 303 303 VAL VAL B . n B 1 89 SER 89 304 304 SER SER B . n B 1 90 VAL 90 305 305 VAL VAL B . n B 1 91 LEU 91 306 306 LEU LEU B . n B 1 92 THR 92 307 307 THR THR B . n B 1 93 VAL 93 308 308 VAL VAL B . n B 1 94 LEU 94 309 309 LEU LEU B . n B 1 95 HIS 95 310 310 HIS HIS B . n B 1 96 GLN 96 311 311 GLN GLN B . n B 1 97 ASP 97 312 312 ASP ASP B . n B 1 98 TRP 98 313 313 TRP TRP B . n B 1 99 LEU 99 314 314 LEU LEU B . n B 1 100 ASN 100 315 315 ASN ASN B . n B 1 101 GLY 101 316 316 GLY GLY B . n B 1 102 LYS 102 317 317 LYS LYS B . n B 1 103 GLU 103 318 318 GLU GLU B . n B 1 104 TYR 104 319 319 TYR TYR B . n B 1 105 LYS 105 320 320 LYS LYS B . n B 1 106 CYS 106 321 321 CYS CYS B . n B 1 107 LYS 107 322 322 LYS LYS B . n B 1 108 VAL 108 323 323 VAL VAL B . n B 1 109 SER 109 324 324 SER SER B . n B 1 110 ASN 110 325 325 ASN ASN B . n B 1 111 LYS 111 326 326 LYS LYS B . n B 1 112 ALA 112 327 327 ALA ALA B . n B 1 113 LEU 113 328 328 LEU LEU B . n B 1 114 PRO 114 329 329 PRO PRO B . n B 1 115 ALA 115 330 330 ALA ALA B . n B 1 116 PRO 116 331 331 PRO PRO B . n B 1 117 ILE 117 332 332 ILE ILE B . n B 1 118 GLU 118 333 333 GLU GLU B . n B 1 119 LYS 119 334 334 LYS LYS B . n B 1 120 THR 120 335 335 THR THR B . n B 1 121 ILE 121 336 336 ILE ILE B . n B 1 122 SER 122 337 337 SER SER B . n B 1 123 LYS 123 338 338 LYS LYS B . n B 1 124 ALA 124 339 339 ALA ALA B . n B 1 125 LYS 125 340 340 LYS LYS B . n B 1 126 GLY 126 341 341 GLY GLY B . n B 1 127 GLN 127 342 342 GLN GLN B . n B 1 128 PRO 128 343 343 PRO PRO B . n B 1 129 ARG 129 344 344 ARG ARG B . n B 1 130 GLU 130 345 345 GLU GLU B . n B 1 131 PRO 131 346 346 PRO PRO B . n B 1 132 GLN 132 347 347 GLN GLN B . n B 1 133 VAL 133 348 348 VAL VAL B . n B 1 134 TYR 134 349 349 TYR TYR B . n B 1 135 THR 135 350 350 THR THR B . n B 1 136 LEU 136 351 351 LEU LEU B . n B 1 137 PRO 137 352 352 PRO PRO B . n B 1 138 PRO 138 353 353 PRO PRO B . n B 1 139 SER 139 354 354 SER SER B . n B 1 140 ARG 140 355 355 ARG ARG B . n B 1 141 ASP 141 356 356 ASP ASP B . n B 1 142 GLU 142 357 357 GLU GLU B . n B 1 143 LEU 143 358 358 LEU LEU B . n B 1 144 THR 144 359 359 THR THR B . n B 1 145 LYS 145 360 360 LYS LYS B . n B 1 146 ASN 146 361 361 ASN ASN B . n B 1 147 GLN 147 362 362 GLN GLN B . n B 1 148 VAL 148 363 363 VAL VAL B . n B 1 149 SER 149 364 364 SER SER B . n B 1 150 LEU 150 365 365 LEU LEU B . n B 1 151 THR 151 366 366 THR THR B . n B 1 152 CYS 152 367 367 CYS CYS B . n B 1 153 LEU 153 368 368 LEU LEU B . n B 1 154 VAL 154 369 369 VAL VAL B . n B 1 155 LYS 155 370 370 LYS LYS B . n B 1 156 GLY 156 371 371 GLY GLY B . n B 1 157 PHE 157 372 372 PHE PHE B . n B 1 158 TYR 158 373 373 TYR TYR B . n B 1 159 PRO 159 374 374 PRO PRO B . n B 1 160 SER 160 375 375 SER SER B . n B 1 161 ASP 161 376 376 ASP ASP B . n B 1 162 ILE 162 377 377 ILE ILE B . n B 1 163 ALA 163 378 378 ALA ALA B . n B 1 164 VAL 164 379 379 VAL VAL B . n B 1 165 GLU 165 380 380 GLU GLU B . n B 1 166 TRP 166 381 381 TRP TRP B . n B 1 167 GLU 167 382 382 GLU GLU B . n B 1 168 SER 168 383 383 SER SER B . n B 1 169 ASN 169 384 384 ASN ASN B . n B 1 170 GLY 170 385 385 GLY GLY B . n B 1 171 GLN 171 386 386 GLN GLN B . n B 1 172 PRO 172 387 387 PRO PRO B . n B 1 173 GLU 173 388 388 GLU GLU B . n B 1 174 ASN 174 389 389 ASN ASN B . n B 1 175 ASN 175 390 390 ASN ASN B . n B 1 176 TYR 176 391 391 TYR TYR B . n B 1 177 LYS 177 392 392 LYS LYS B . n B 1 178 THR 178 393 393 THR THR B . n B 1 179 THR 179 394 394 THR THR B . n B 1 180 PRO 180 395 395 PRO PRO B . n B 1 181 PRO 181 396 396 PRO PRO B . n B 1 182 VAL 182 397 397 VAL VAL B . n B 1 183 LEU 183 398 398 LEU LEU B . n B 1 184 ASP 184 399 399 ASP ASP B . n B 1 185 SER 185 400 400 SER SER B . n B 1 186 ASP 186 401 401 ASP ASP B . n B 1 187 GLY 187 402 402 GLY GLY B . n B 1 188 SER 188 403 403 SER SER B . n B 1 189 PHE 189 404 404 PHE PHE B . n B 1 190 PHE 190 405 405 PHE PHE B . n B 1 191 LEU 191 406 406 LEU LEU B . n B 1 192 TYR 192 407 407 TYR TYR B . n B 1 193 SER 193 408 408 SER SER B . n B 1 194 LYS 194 409 409 LYS LYS B . n B 1 195 LEU 195 410 410 LEU LEU B . n B 1 196 THR 196 411 411 THR THR B . n B 1 197 VAL 197 412 412 VAL VAL B . n B 1 198 ASP 198 413 413 ASP ASP B . n B 1 199 LYS 199 414 414 LYS LYS B . n B 1 200 SER 200 415 415 SER SER B . n B 1 201 ARG 201 416 416 ARG ARG B . n B 1 202 TRP 202 417 417 TRP TRP B . n B 1 203 GLN 203 418 418 GLN GLN B . n B 1 204 GLN 204 419 419 GLN GLN B . n B 1 205 GLY 205 420 420 GLY GLY B . n B 1 206 ASN 206 421 421 ASN ASN B . n B 1 207 VAL 207 422 422 VAL VAL B . n B 1 208 PHE 208 423 423 PHE PHE B . n B 1 209 SER 209 424 424 SER SER B . n B 1 210 CYS 210 425 425 CYS CYS B . n B 1 211 SER 211 426 426 SER SER B . n B 1 212 VAL 212 427 427 VAL VAL B . n B 1 213 MET 213 428 428 MET MET B . n B 1 214 HIS 214 429 429 HIS HIS B . n B 1 215 GLU 215 430 430 GLU GLU B . n B 1 216 ALA 216 431 431 ALA ALA B . n B 1 217 LEU 217 432 432 LEU LEU B . n B 1 218 HIS 218 433 433 HIS HIS B . n B 1 219 ASN 219 434 434 ASN ASN B . n B 1 220 HIS 220 435 435 HIS HIS B . n B 1 221 TYR 221 436 436 TYR TYR B . n B 1 222 THR 222 437 437 THR THR B . n B 1 223 GLN 223 438 438 GLN GLN B . n B 1 224 LYS 224 439 439 LYS LYS B . n B 1 225 SER 225 440 440 SER SER B . n B 1 226 LEU 226 441 441 LEU LEU B . n B 1 227 SER 227 442 442 SER SER B . n B 1 228 LEU 228 443 443 LEU LEU B . n B 1 229 SER 229 444 444 SER SER B . n B 1 230 PRO 230 445 445 PRO PRO B . n B 1 231 GLY 231 446 446 GLY GLY B . n B 1 232 LYS 232 447 ? ? ? B . n C 2 1 LEU 1 -10 ? ? ? H . n C 2 2 LEU 2 -9 ? ? ? H . n C 2 3 LEU 3 -8 ? ? ? H . n C 2 4 VAL 4 -7 ? ? ? H . n C 2 5 ALA 5 -6 ? ? ? H . n C 2 6 ALA 6 -5 ? ? ? H . n C 2 7 PRO 7 -4 ? ? ? H . n C 2 8 ARG 8 -3 ? ? ? H . n C 2 9 TRP 9 -2 ? ? ? H . n C 2 10 LEU 10 -1 ? ? ? H . n C 2 11 SER 11 0 ? ? ? H . n C 2 12 GLN 12 1 1 GLN GLN H . n C 2 13 LEU 13 2 2 LEU LEU H . n C 2 14 GLN 14 3 3 GLN GLN H . n C 2 15 LEU 15 4 4 LEU LEU H . n C 2 16 GLN 16 5 5 GLN GLN H . n C 2 17 GLU 17 6 6 GLU GLU H . n C 2 18 SER 18 7 7 SER SER H . n C 2 19 GLY 19 8 8 GLY GLY H . n C 2 20 PRO 20 9 9 PRO PRO H . n C 2 21 GLY 21 10 10 GLY GLY H . n C 2 22 LEU 22 11 11 LEU LEU H . n C 2 23 VAL 23 12 12 VAL VAL H . n C 2 24 LYS 24 13 13 LYS LYS H . n C 2 25 PRO 25 14 14 PRO PRO H . n C 2 26 SER 26 15 15 SER SER H . n C 2 27 GLU 27 16 16 GLU GLU H . n C 2 28 THR 28 17 17 THR THR H . n C 2 29 LEU 29 18 18 LEU LEU H . n C 2 30 SER 30 19 19 SER SER H . n C 2 31 LEU 31 20 20 LEU LEU H . n C 2 32 THR 32 21 21 THR THR H . n C 2 33 CYS 33 22 22 CYS CYS H . n C 2 34 THR 34 23 23 THR THR H . n C 2 35 VAL 35 24 24 VAL VAL H . n C 2 36 SER 36 25 25 SER SER H . n C 2 37 GLY 37 26 26 GLY GLY H . n C 2 38 GLY 38 27 27 GLY GLY H . n C 2 39 SER 39 28 28 SER SER H . n C 2 40 ILE 40 29 29 ILE ILE H . n C 2 41 SER 41 30 30 SER SER H . n C 2 42 ARG 42 31 31 ARG ARG H . n C 2 43 GLY 43 32 32 GLY GLY H . n C 2 44 SER 44 33 33 SER SER H . n C 2 45 HIS 45 34 34 HIS HIS H . n C 2 46 TYR 46 35 35 TYR TYR H . n C 2 47 TRP 47 35 35 TRP TRP H A n C 2 48 GLY 48 35 35 GLY GLY H B n C 2 49 TRP 49 36 36 TRP TRP H . n C 2 50 ILE 50 37 37 ILE ILE H . n C 2 51 ARG 51 38 38 ARG ARG H . n C 2 52 GLN 52 39 39 GLN GLN H . n C 2 53 PRO 53 40 40 PRO PRO H . n C 2 54 PRO 54 41 41 PRO PRO H . n C 2 55 GLY 55 42 42 GLY GLY H . n C 2 56 LYS 56 43 43 LYS LYS H . n C 2 57 GLY 57 44 44 GLY GLY H . n C 2 58 LEU 58 45 45 LEU LEU H . n C 2 59 GLU 59 46 46 GLU GLU H . n C 2 60 TRP 60 47 47 TRP TRP H . n C 2 61 ILE 61 48 48 ILE ILE H . n C 2 62 GLY 62 49 49 GLY GLY H . n C 2 63 SER 63 50 50 SER SER H . n C 2 64 ILE 64 51 51 ILE ILE H . n C 2 65 TYR 65 52 52 TYR TYR H . n C 2 66 TYR 66 53 53 TYR TYR H . n C 2 67 SER 67 54 54 SER SER H . n C 2 68 GLY 68 55 55 GLY GLY H . n C 2 69 ASN 69 56 56 ASN ASN H . n C 2 70 THR 70 57 57 THR THR H . n C 2 71 TYR 71 58 58 TYR TYR H . n C 2 72 PHE 72 59 59 PHE PHE H . n C 2 73 ASN 73 60 60 ASN ASN H . n C 2 74 PRO 74 61 61 PRO PRO H . n C 2 75 SER 75 62 62 SER SER H . n C 2 76 LEU 76 63 63 LEU LEU H . n C 2 77 LYS 77 64 64 LYS LYS H . n C 2 78 SER 78 65 65 SER SER H . n C 2 79 ARG 79 66 66 ARG ARG H . n C 2 80 VAL 80 67 67 VAL VAL H . n C 2 81 THR 81 68 68 THR THR H . n C 2 82 ILE 82 69 69 ILE ILE H . n C 2 83 SER 83 70 70 SER SER H . n C 2 84 VAL 84 71 71 VAL VAL H . n C 2 85 ASP 85 72 72 ASP ASP H . n C 2 86 THR 86 73 73 THR THR H . n C 2 87 SER 87 74 74 SER SER H . n C 2 88 LYS 88 75 75 LYS LYS H . n C 2 89 ASN 89 76 76 ASN ASN H . n C 2 90 GLN 90 77 77 GLN GLN H . n C 2 91 PHE 91 78 78 PHE PHE H . n C 2 92 SER 92 79 79 SER SER H . n C 2 93 LEU 93 80 80 LEU LEU H . n C 2 94 LYS 94 81 81 LYS LYS H . n C 2 95 LEU 95 82 82 LEU LEU H . n C 2 96 SER 96 82 82 SER SER H A n C 2 97 SER 97 82 82 SER SER H B n C 2 98 VAL 98 82 82 VAL VAL H C n C 2 99 THR 99 83 83 THR THR H . n C 2 100 ALA 100 84 84 ALA ALA H . n C 2 101 ALA 101 85 85 ALA ALA H . n C 2 102 ASP 102 86 86 ASP ASP H . n C 2 103 THR 103 87 87 THR THR H . n C 2 104 ALA 104 88 88 ALA ALA H . n C 2 105 VAL 105 89 89 VAL VAL H . n C 2 106 TYR 106 90 90 TYR TYR H . n C 2 107 TYR 107 91 91 TYR TYR H . n C 2 108 CYS 108 92 92 CYS CYS H . n C 2 109 ALA 109 93 93 ALA ALA H . n C 2 110 ARG 110 94 94 ARG ARG H . n C 2 111 LEU 111 95 95 LEU LEU H . n C 2 112 GLY 112 96 96 GLY GLY H . n C 2 113 PRO 113 97 97 PRO PRO H . n C 2 114 ASP 114 98 98 ASP ASP H . n C 2 115 ASP 115 99 99 ASP ASP H . n C 2 116 TYR 116 100 100 TYR TYR H . n C 2 117 THR 117 100 100 THR THR H A n C 2 118 LEU 118 100 100 LEU LEU H B n C 2 119 ASP 119 100 100 ASP ASP H C n C 2 120 GLY 120 100 100 GLY GLY H D n C 2 121 MET 121 100 100 MET MET H E n C 2 122 ASP 122 101 101 ASP ASP H . n C 2 123 VAL 123 102 102 VAL VAL H . n C 2 124 TRP 124 103 103 TRP TRP H . n C 2 125 GLY 125 104 104 GLY GLY H . n C 2 126 GLN 126 105 105 GLN GLN H . n C 2 127 GLY 127 106 106 GLY GLY H . n C 2 128 THR 128 107 107 THR THR H . n C 2 129 THR 129 108 108 THR THR H . n C 2 130 VAL 130 109 109 VAL VAL H . n C 2 131 THR 131 110 110 THR THR H . n C 2 132 VAL 132 111 111 VAL VAL H . n C 2 133 SER 133 112 112 SER SER H . n C 2 134 SER 134 113 113 SER SER H . n C 2 135 GLY 135 114 114 GLY GLY H . n C 2 136 SER 136 115 115 SER SER H . n C 2 137 ALA 137 116 116 ALA ALA H . n C 2 138 SER 138 117 117 SER SER H . n C 2 139 ALA 139 118 118 ALA ALA H . n C 2 140 PRO 140 119 119 PRO PRO H . n C 2 141 THR 141 120 120 THR THR H . n C 2 142 LEU 142 121 121 LEU LEU H . n C 2 143 PHE 143 122 122 PHE PHE H . n C 2 144 PRO 144 123 123 PRO PRO H . n C 2 145 LEU 145 124 124 LEU LEU H . n C 2 146 VAL 146 125 125 VAL VAL H . n C 2 147 SER 147 130 ? ? ? H . n C 2 148 CYS 148 131 ? ? ? H . n C 2 149 ASP 149 132 ? ? ? H . n C 2 150 THR 150 133 ? ? ? H . n C 2 151 SER 151 134 134 SER SER H . n C 2 152 SER 152 135 135 SER SER H . n C 2 153 VAL 153 136 136 VAL VAL H . n C 2 154 ALA 154 137 137 ALA ALA H . n C 2 155 VAL 155 138 138 VAL VAL H . n C 2 156 GLY 156 139 139 GLY GLY H . n C 2 157 CYS 157 140 140 CYS CYS H . n C 2 158 LEU 158 141 141 LEU LEU H . n C 2 159 ALA 159 142 142 ALA ALA H . n C 2 160 GLN 160 143 143 GLN GLN H . n C 2 161 ASP 161 144 144 ASP ASP H . n C 2 162 PHE 162 145 145 PHE PHE H . n C 2 163 LEU 163 146 146 LEU LEU H . n C 2 164 PRO 164 147 147 PRO PRO H . n C 2 165 ASP 165 148 148 ASP ASP H . n C 2 166 SER 166 149 149 SER SER H . n C 2 167 ILE 167 150 150 ILE ILE H . n C 2 168 THR 168 151 151 THR THR H . n C 2 169 PHE 169 152 152 PHE PHE H . n C 2 170 SER 170 153 153 SER SER H . n C 2 171 TRP 171 154 154 TRP TRP H . n C 2 172 LYS 172 155 155 LYS LYS H . n C 2 173 TYR 173 156 156 TYR TYR H . n C 2 174 LYS 174 157 157 LYS LYS H . n C 2 175 ASN 175 158 158 ASN ASN H . n C 2 176 ASN 176 159 159 ASN ASN H . n C 2 177 SER 177 160 160 SER SER H . n C 2 178 ASP 178 161 161 ASP ASP H . n C 2 179 ILE 179 162 162 ILE ILE H . n C 2 180 SER 180 163 163 SER SER H . n C 2 181 SER 181 164 164 SER SER H . n C 2 182 THR 182 165 165 THR THR H . n C 2 183 ARG 183 166 166 ARG ARG H . n C 2 184 GLY 184 167 167 GLY GLY H . n C 2 185 PHE 185 168 168 PHE PHE H . n C 2 186 PRO 186 169 169 PRO PRO H . n C 2 187 SER 187 170 170 SER SER H . n C 2 188 VAL 188 171 171 VAL VAL H . n C 2 189 LEU 189 172 172 LEU LEU H . n C 2 190 ARG 190 173 173 ARG ARG H . n C 2 191 GLY 191 174 174 GLY GLY H . n C 2 192 GLY 192 175 175 GLY GLY H . n C 2 193 LYS 193 176 176 LYS LYS H . n C 2 194 TYR 194 177 177 TYR TYR H . n C 2 195 ALA 195 178 178 ALA ALA H . n C 2 196 ALA 196 179 179 ALA ALA H . n C 2 197 THR 197 180 180 THR THR H . n C 2 198 SER 198 181 181 SER SER H . n C 2 199 GLN 199 182 182 GLN GLN H . n C 2 200 VAL 200 183 183 VAL VAL H . n C 2 201 LEU 201 184 184 LEU LEU H . n C 2 202 LEU 202 185 185 LEU LEU H . n C 2 203 PRO 203 186 186 PRO PRO H . n C 2 204 SER 204 187 187 SER SER H . n C 2 205 LYS 205 188 188 LYS LYS H . n C 2 206 ASP 206 189 189 ASP ASP H . n C 2 207 VAL 207 190 190 VAL VAL H . n C 2 208 MET 208 191 191 MET MET H . n C 2 209 GLN 209 192 192 GLN GLN H . n C 2 210 GLY 210 193 193 GLY GLY H . n C 2 211 THR 211 194 194 THR THR H . n C 2 212 ASP 212 195 195 ASP ASP H . n C 2 213 GLU 213 196 196 GLU GLU H . n C 2 214 HIS 214 197 197 HIS HIS H . n C 2 215 VAL 215 198 198 VAL VAL H . n C 2 216 VAL 216 199 199 VAL VAL H . n C 2 217 CYS 217 200 200 CYS CYS H . n C 2 218 LYS 218 201 201 LYS LYS H . n C 2 219 VAL 219 202 202 VAL VAL H . n C 2 220 GLN 220 203 203 GLN GLN H . n C 2 221 HIS 221 204 204 HIS HIS H . n C 2 222 PRO 222 205 205 PRO PRO H . n C 2 223 ASN 223 206 206 ASN ASN H . n C 2 224 GLY 224 207 207 GLY GLY H . n C 2 225 ASN 225 208 208 ASN ASN H . n C 2 226 LYS 226 209 209 LYS LYS H . n C 2 227 GLU 227 210 210 GLU GLU H . n C 2 228 LYS 228 211 211 LYS LYS H . n C 2 229 ASN 229 212 212 ASN ASN H . n C 2 230 VAL 230 213 213 VAL VAL H . n C 2 231 PRO 231 214 214 PRO PRO H . n D 2 1 LEU 1 -10 ? ? ? I . n D 2 2 LEU 2 -9 ? ? ? I . n D 2 3 LEU 3 -8 ? ? ? I . n D 2 4 VAL 4 -7 ? ? ? I . n D 2 5 ALA 5 -6 ? ? ? I . n D 2 6 ALA 6 -5 ? ? ? I . n D 2 7 PRO 7 -4 ? ? ? I . n D 2 8 ARG 8 -3 ? ? ? I . n D 2 9 TRP 9 -2 ? ? ? I . n D 2 10 LEU 10 -1 ? ? ? I . n D 2 11 SER 11 0 ? ? ? I . n D 2 12 GLN 12 1 1 GLN GLN I . n D 2 13 LEU 13 2 2 LEU LEU I . n D 2 14 GLN 14 3 3 GLN GLN I . n D 2 15 LEU 15 4 4 LEU LEU I . n D 2 16 GLN 16 5 5 GLN GLN I . n D 2 17 GLU 17 6 6 GLU GLU I . n D 2 18 SER 18 7 7 SER SER I . n D 2 19 GLY 19 8 8 GLY GLY I . n D 2 20 PRO 20 9 9 PRO PRO I . n D 2 21 GLY 21 10 10 GLY GLY I . n D 2 22 LEU 22 11 11 LEU LEU I . n D 2 23 VAL 23 12 12 VAL VAL I . n D 2 24 LYS 24 13 13 LYS LYS I . n D 2 25 PRO 25 14 14 PRO PRO I . n D 2 26 SER 26 15 15 SER SER I . n D 2 27 GLU 27 16 16 GLU GLU I . n D 2 28 THR 28 17 17 THR THR I . n D 2 29 LEU 29 18 18 LEU LEU I . n D 2 30 SER 30 19 19 SER SER I . n D 2 31 LEU 31 20 20 LEU LEU I . n D 2 32 THR 32 21 21 THR THR I . n D 2 33 CYS 33 22 22 CYS CYS I . n D 2 34 THR 34 23 23 THR THR I . n D 2 35 VAL 35 24 24 VAL VAL I . n D 2 36 SER 36 25 25 SER SER I . n D 2 37 GLY 37 26 26 GLY GLY I . n D 2 38 GLY 38 27 27 GLY GLY I . n D 2 39 SER 39 28 28 SER SER I . n D 2 40 ILE 40 29 29 ILE ILE I . n D 2 41 SER 41 30 30 SER SER I . n D 2 42 ARG 42 31 31 ARG ARG I . n D 2 43 GLY 43 32 32 GLY GLY I . n D 2 44 SER 44 33 33 SER SER I . n D 2 45 HIS 45 34 34 HIS HIS I . n D 2 46 TYR 46 35 35 TYR TYR I . n D 2 47 TRP 47 35 35 TRP TRP I A n D 2 48 GLY 48 35 35 GLY GLY I B n D 2 49 TRP 49 36 36 TRP TRP I . n D 2 50 ILE 50 37 37 ILE ILE I . n D 2 51 ARG 51 38 38 ARG ARG I . n D 2 52 GLN 52 39 39 GLN GLN I . n D 2 53 PRO 53 40 40 PRO PRO I . n D 2 54 PRO 54 41 41 PRO PRO I . n D 2 55 GLY 55 42 42 GLY GLY I . n D 2 56 LYS 56 43 43 LYS LYS I . n D 2 57 GLY 57 44 44 GLY GLY I . n D 2 58 LEU 58 45 45 LEU LEU I . n D 2 59 GLU 59 46 46 GLU GLU I . n D 2 60 TRP 60 47 47 TRP TRP I . n D 2 61 ILE 61 48 48 ILE ILE I . n D 2 62 GLY 62 49 49 GLY GLY I . n D 2 63 SER 63 50 50 SER SER I . n D 2 64 ILE 64 51 51 ILE ILE I . n D 2 65 TYR 65 52 52 TYR TYR I . n D 2 66 TYR 66 53 53 TYR TYR I . n D 2 67 SER 67 54 54 SER SER I . n D 2 68 GLY 68 55 55 GLY GLY I . n D 2 69 ASN 69 56 56 ASN ASN I . n D 2 70 THR 70 57 57 THR THR I . n D 2 71 TYR 71 58 58 TYR TYR I . n D 2 72 PHE 72 59 59 PHE PHE I . n D 2 73 ASN 73 60 60 ASN ASN I . n D 2 74 PRO 74 61 61 PRO PRO I . n D 2 75 SER 75 62 62 SER SER I . n D 2 76 LEU 76 63 63 LEU LEU I . n D 2 77 LYS 77 64 64 LYS LYS I . n D 2 78 SER 78 65 65 SER SER I . n D 2 79 ARG 79 66 66 ARG ARG I . n D 2 80 VAL 80 67 67 VAL VAL I . n D 2 81 THR 81 68 68 THR THR I . n D 2 82 ILE 82 69 69 ILE ILE I . n D 2 83 SER 83 70 70 SER SER I . n D 2 84 VAL 84 71 71 VAL VAL I . n D 2 85 ASP 85 72 72 ASP ASP I . n D 2 86 THR 86 73 73 THR THR I . n D 2 87 SER 87 74 74 SER SER I . n D 2 88 LYS 88 75 75 LYS LYS I . n D 2 89 ASN 89 76 76 ASN ASN I . n D 2 90 GLN 90 77 77 GLN GLN I . n D 2 91 PHE 91 78 78 PHE PHE I . n D 2 92 SER 92 79 79 SER SER I . n D 2 93 LEU 93 80 80 LEU LEU I . n D 2 94 LYS 94 81 81 LYS LYS I . n D 2 95 LEU 95 82 82 LEU LEU I . n D 2 96 SER 96 82 82 SER SER I A n D 2 97 SER 97 82 82 SER SER I B n D 2 98 VAL 98 82 82 VAL VAL I C n D 2 99 THR 99 83 83 THR THR I . n D 2 100 ALA 100 84 84 ALA ALA I . n D 2 101 ALA 101 85 85 ALA ALA I . n D 2 102 ASP 102 86 86 ASP ASP I . n D 2 103 THR 103 87 87 THR THR I . n D 2 104 ALA 104 88 88 ALA ALA I . n D 2 105 VAL 105 89 89 VAL VAL I . n D 2 106 TYR 106 90 90 TYR TYR I . n D 2 107 TYR 107 91 91 TYR TYR I . n D 2 108 CYS 108 92 92 CYS CYS I . n D 2 109 ALA 109 93 93 ALA ALA I . n D 2 110 ARG 110 94 94 ARG ARG I . n D 2 111 LEU 111 95 95 LEU LEU I . n D 2 112 GLY 112 96 96 GLY GLY I . n D 2 113 PRO 113 97 97 PRO PRO I . n D 2 114 ASP 114 98 98 ASP ASP I . n D 2 115 ASP 115 99 99 ASP ASP I . n D 2 116 TYR 116 100 100 TYR TYR I . n D 2 117 THR 117 100 100 THR THR I A n D 2 118 LEU 118 100 100 LEU LEU I B n D 2 119 ASP 119 100 100 ASP ASP I C n D 2 120 GLY 120 100 100 GLY GLY I D n D 2 121 MET 121 100 100 MET MET I E n D 2 122 ASP 122 101 101 ASP ASP I . n D 2 123 VAL 123 102 102 VAL VAL I . n D 2 124 TRP 124 103 103 TRP TRP I . n D 2 125 GLY 125 104 104 GLY GLY I . n D 2 126 GLN 126 105 105 GLN GLN I . n D 2 127 GLY 127 106 106 GLY GLY I . n D 2 128 THR 128 107 107 THR THR I . n D 2 129 THR 129 108 108 THR THR I . n D 2 130 VAL 130 109 109 VAL VAL I . n D 2 131 THR 131 110 110 THR THR I . n D 2 132 VAL 132 111 111 VAL VAL I . n D 2 133 SER 133 112 112 SER SER I . n D 2 134 SER 134 113 113 SER SER I . n D 2 135 GLY 135 114 114 GLY GLY I . n D 2 136 SER 136 115 115 SER SER I . n D 2 137 ALA 137 116 116 ALA ALA I . n D 2 138 SER 138 117 117 SER SER I . n D 2 139 ALA 139 118 118 ALA ALA I . n D 2 140 PRO 140 119 119 PRO PRO I . n D 2 141 THR 141 120 120 THR THR I . n D 2 142 LEU 142 121 121 LEU LEU I . n D 2 143 PHE 143 122 122 PHE PHE I . n D 2 144 PRO 144 123 123 PRO PRO I . n D 2 145 LEU 145 124 124 LEU LEU I . n D 2 146 VAL 146 125 125 VAL VAL I . n D 2 147 SER 147 126 126 SER SER I . n D 2 148 CYS 148 127 127 CYS CYS I . n D 2 149 ASP 149 132 132 ASP ASP I . n D 2 150 THR 150 133 133 THR THR I . n D 2 151 SER 151 134 134 SER SER I . n D 2 152 SER 152 135 135 SER SER I . n D 2 153 VAL 153 136 136 VAL VAL I . n D 2 154 ALA 154 137 137 ALA ALA I . n D 2 155 VAL 155 138 138 VAL VAL I . n D 2 156 GLY 156 139 139 GLY GLY I . n D 2 157 CYS 157 140 140 CYS CYS I . n D 2 158 LEU 158 141 141 LEU LEU I . n D 2 159 ALA 159 142 142 ALA ALA I . n D 2 160 GLN 160 143 143 GLN GLN I . n D 2 161 ASP 161 144 144 ASP ASP I . n D 2 162 PHE 162 145 145 PHE PHE I . n D 2 163 LEU 163 146 146 LEU LEU I . n D 2 164 PRO 164 147 147 PRO PRO I . n D 2 165 ASP 165 148 148 ASP ASP I . n D 2 166 SER 166 149 149 SER SER I . n D 2 167 ILE 167 150 150 ILE ILE I . n D 2 168 THR 168 151 151 THR THR I . n D 2 169 PHE 169 152 152 PHE PHE I . n D 2 170 SER 170 153 153 SER SER I . n D 2 171 TRP 171 154 154 TRP TRP I . n D 2 172 LYS 172 155 155 LYS LYS I . n D 2 173 TYR 173 156 156 TYR TYR I . n D 2 174 LYS 174 157 157 LYS LYS I . n D 2 175 ASN 175 158 158 ASN ASN I . n D 2 176 ASN 176 159 159 ASN ASN I . n D 2 177 SER 177 160 160 SER SER I . n D 2 178 ASP 178 161 161 ASP ASP I . n D 2 179 ILE 179 162 162 ILE ILE I . n D 2 180 SER 180 163 163 SER SER I . n D 2 181 SER 181 164 164 SER SER I . n D 2 182 THR 182 165 165 THR THR I . n D 2 183 ARG 183 166 166 ARG ARG I . n D 2 184 GLY 184 167 167 GLY GLY I . n D 2 185 PHE 185 168 168 PHE PHE I . n D 2 186 PRO 186 169 169 PRO PRO I . n D 2 187 SER 187 170 170 SER SER I . n D 2 188 VAL 188 171 171 VAL VAL I . n D 2 189 LEU 189 172 172 LEU LEU I . n D 2 190 ARG 190 173 173 ARG ARG I . n D 2 191 GLY 191 174 174 GLY GLY I . n D 2 192 GLY 192 175 175 GLY GLY I . n D 2 193 LYS 193 176 176 LYS LYS I . n D 2 194 TYR 194 177 177 TYR TYR I . n D 2 195 ALA 195 178 178 ALA ALA I . n D 2 196 ALA 196 179 179 ALA ALA I . n D 2 197 THR 197 180 180 THR THR I . n D 2 198 SER 198 181 181 SER SER I . n D 2 199 GLN 199 182 182 GLN GLN I . n D 2 200 VAL 200 183 183 VAL VAL I . n D 2 201 LEU 201 184 184 LEU LEU I . n D 2 202 LEU 202 185 185 LEU LEU I . n D 2 203 PRO 203 186 186 PRO PRO I . n D 2 204 SER 204 187 187 SER SER I . n D 2 205 LYS 205 188 188 LYS LYS I . n D 2 206 ASP 206 189 189 ASP ASP I . n D 2 207 VAL 207 190 190 VAL VAL I . n D 2 208 MET 208 191 191 MET MET I . n D 2 209 GLN 209 192 192 GLN GLN I . n D 2 210 GLY 210 193 193 GLY GLY I . n D 2 211 THR 211 194 194 THR THR I . n D 2 212 ASP 212 195 195 ASP ASP I . n D 2 213 GLU 213 196 196 GLU GLU I . n D 2 214 HIS 214 197 197 HIS HIS I . n D 2 215 VAL 215 198 198 VAL VAL I . n D 2 216 VAL 216 199 199 VAL VAL I . n D 2 217 CYS 217 200 200 CYS CYS I . n D 2 218 LYS 218 201 201 LYS LYS I . n D 2 219 VAL 219 202 202 VAL VAL I . n D 2 220 GLN 220 203 203 GLN GLN I . n D 2 221 HIS 221 204 204 HIS HIS I . n D 2 222 PRO 222 205 205 PRO PRO I . n D 2 223 ASN 223 206 206 ASN ASN I . n D 2 224 GLY 224 207 207 GLY GLY I . n D 2 225 ASN 225 208 208 ASN ASN I . n D 2 226 LYS 226 209 209 LYS LYS I . n D 2 227 GLU 227 210 210 GLU GLU I . n D 2 228 LYS 228 211 211 LYS LYS I . n D 2 229 ASN 229 212 212 ASN ASN I . n D 2 230 VAL 230 213 213 VAL VAL I . n D 2 231 PRO 231 214 214 PRO PRO I . n E 3 1 MET 1 -18 ? ? ? L . n E 3 2 ALA 2 -17 ? ? ? L . n E 3 3 GLY 3 -16 ? ? ? L . n E 3 4 PHE 4 -15 ? ? ? L . n E 3 5 PRO 5 -14 ? ? ? L . n E 3 6 LEU 6 -13 ? ? ? L . n E 3 7 LEU 7 -12 ? ? ? L . n E 3 8 LEU 8 -11 ? ? ? L . n E 3 9 THR 9 -10 ? ? ? L . n E 3 10 LEU 10 -9 ? ? ? L . n E 3 11 LEU 11 -8 ? ? ? L . n E 3 12 THR 12 -7 ? ? ? L . n E 3 13 HIS 13 -6 ? ? ? L . n E 3 14 CYS 14 -5 ? ? ? L . n E 3 15 ALA 15 -4 ? ? ? L . n E 3 16 GLY 16 -3 ? ? ? L . n E 3 17 SER 17 -2 ? ? ? L . n E 3 18 TRP 18 -1 ? ? ? L . n E 3 19 ALA 19 0 ? ? ? L . n E 3 20 GLN 20 1 1 GLN GLN L . n E 3 21 SER 21 2 2 SER SER L . n E 3 22 VAL 22 3 3 VAL VAL L . n E 3 23 LEU 23 4 4 LEU LEU L . n E 3 24 THR 24 5 5 THR THR L . n E 3 25 GLN 25 6 6 GLN GLN L . n E 3 26 PRO 26 7 7 PRO PRO L . n E 3 27 PRO 27 8 8 PRO PRO L . n E 3 28 SER 28 9 9 SER SER L . n E 3 29 ALA 29 10 10 ALA ALA L . n E 3 30 SER 30 11 11 SER SER L . n E 3 31 GLY 31 12 12 GLY GLY L . n E 3 32 THR 32 13 13 THR THR L . n E 3 33 PRO 33 14 14 PRO PRO L . n E 3 34 GLY 34 15 15 GLY GLY L . n E 3 35 GLN 35 16 16 GLN GLN L . n E 3 36 ARG 36 17 17 ARG ARG L . n E 3 37 VAL 37 18 18 VAL VAL L . n E 3 38 THR 38 19 19 THR THR L . n E 3 39 ILE 39 20 20 ILE ILE L . n E 3 40 SER 40 21 21 SER SER L . n E 3 41 CYS 41 22 22 CYS CYS L . n E 3 42 SER 42 23 23 SER SER L . n E 3 43 GLY 43 24 24 GLY GLY L . n E 3 44 SER 44 25 25 SER SER L . n E 3 45 SER 45 26 26 SER SER L . n E 3 46 SER 46 27 27 SER SER L . n E 3 47 ASN 47 27 27 ASN ASN L A n E 3 48 ILE 48 28 28 ILE ILE L . n E 3 49 GLY 49 29 29 GLY GLY L . n E 3 50 SER 50 30 30 SER SER L . n E 3 51 ASN 51 31 31 ASN ASN L . n E 3 52 TYR 52 32 32 TYR TYR L . n E 3 53 VAL 53 33 33 VAL VAL L . n E 3 54 TYR 54 34 34 TYR TYR L . n E 3 55 TRP 55 35 35 TRP TRP L . n E 3 56 TYR 56 36 36 TYR TYR L . n E 3 57 GLN 57 37 37 GLN GLN L . n E 3 58 GLN 58 38 38 GLN GLN L . n E 3 59 LEU 59 39 39 LEU LEU L . n E 3 60 PRO 60 40 40 PRO PRO L . n E 3 61 GLY 61 41 41 GLY GLY L . n E 3 62 THR 62 42 42 THR THR L . n E 3 63 ALA 63 43 43 ALA ALA L . n E 3 64 PRO 64 44 44 PRO PRO L . n E 3 65 LYS 65 45 45 LYS LYS L . n E 3 66 LEU 66 46 46 LEU LEU L . n E 3 67 LEU 67 47 47 LEU LEU L . n E 3 68 ILE 68 48 48 ILE ILE L . n E 3 69 TYR 69 49 49 TYR TYR L . n E 3 70 ARG 70 50 50 ARG ARG L . n E 3 71 ASN 71 51 51 ASN ASN L . n E 3 72 ASN 72 52 52 ASN ASN L . n E 3 73 GLN 73 53 53 GLN GLN L . n E 3 74 ARG 74 54 54 ARG ARG L . n E 3 75 PRO 75 55 55 PRO PRO L . n E 3 76 SER 76 56 56 SER SER L . n E 3 77 GLY 77 57 57 GLY GLY L . n E 3 78 VAL 78 58 58 VAL VAL L . n E 3 79 PRO 79 59 59 PRO PRO L . n E 3 80 ASP 80 60 60 ASP ASP L . n E 3 81 ARG 81 61 61 ARG ARG L . n E 3 82 PHE 82 62 62 PHE PHE L . n E 3 83 SER 83 63 63 SER SER L . n E 3 84 GLY 84 64 64 GLY GLY L . n E 3 85 SER 85 65 65 SER SER L . n E 3 86 LYS 86 66 66 LYS LYS L . n E 3 87 SER 87 67 67 SER SER L . n E 3 88 GLY 88 68 68 GLY GLY L . n E 3 89 THR 89 69 69 THR THR L . n E 3 90 SER 90 70 70 SER SER L . n E 3 91 ALA 91 71 71 ALA ALA L . n E 3 92 SER 92 72 72 SER SER L . n E 3 93 LEU 93 73 73 LEU LEU L . n E 3 94 ALA 94 74 74 ALA ALA L . n E 3 95 ILE 95 75 75 ILE ILE L . n E 3 96 SER 96 76 76 SER SER L . n E 3 97 GLY 97 77 77 GLY GLY L . n E 3 98 LEU 98 78 78 LEU LEU L . n E 3 99 ARG 99 79 79 ARG ARG L . n E 3 100 SER 100 80 80 SER SER L . n E 3 101 GLU 101 81 81 GLU GLU L . n E 3 102 ASP 102 82 82 ASP ASP L . n E 3 103 GLU 103 83 83 GLU GLU L . n E 3 104 ALA 104 84 84 ALA ALA L . n E 3 105 ASP 105 85 85 ASP ASP L . n E 3 106 TYR 106 86 86 TYR TYR L . n E 3 107 TYR 107 87 87 TYR TYR L . n E 3 108 CYS 108 88 88 CYS CYS L . n E 3 109 ALA 109 89 89 ALA ALA L . n E 3 110 THR 110 90 90 THR THR L . n E 3 111 TRP 111 91 91 TRP TRP L . n E 3 112 ASP 112 92 92 ASP ASP L . n E 3 113 ASP 113 93 93 ASP ASP L . n E 3 114 SER 114 94 94 SER SER L . n E 3 115 LEU 115 95 95 LEU LEU L . n E 3 116 SER 116 95 95 SER SER L A n E 3 117 ALA 117 95 95 ALA ALA L B n E 3 118 VAL 118 96 96 VAL VAL L . n E 3 119 ILE 119 97 97 ILE ILE L . n E 3 120 PHE 120 98 98 PHE PHE L . n E 3 121 GLY 121 99 99 GLY GLY L . n E 3 122 GLY 122 100 100 GLY GLY L . n E 3 123 GLY 123 101 101 GLY GLY L . n E 3 124 THR 124 102 102 THR THR L . n E 3 125 LYS 125 103 103 LYS LYS L . n E 3 126 LEU 126 104 104 LEU LEU L . n E 3 127 THR 127 105 105 THR THR L . n E 3 128 VAL 128 106 106 VAL VAL L . n E 3 129 LEU 129 107 107 LEU LEU L . n E 3 130 GLY 130 108 108 GLY GLY L . n E 3 131 GLN 131 109 109 GLN GLN L . n E 3 132 PRO 132 110 110 PRO PRO L . n E 3 133 LYS 133 110 110 LYS LYS L A n E 3 134 ALA 134 111 111 ALA ALA L . n E 3 135 ALA 135 112 112 ALA ALA L . n E 3 136 PRO 136 113 113 PRO PRO L . n E 3 137 SER 137 114 114 SER SER L . n E 3 138 VAL 138 115 115 VAL VAL L . n E 3 139 THR 139 116 116 THR THR L . n E 3 140 LEU 140 117 117 LEU LEU L . n E 3 141 PHE 141 118 118 PHE PHE L . n E 3 142 PRO 142 119 119 PRO PRO L . n E 3 143 PRO 143 120 120 PRO PRO L . n E 3 144 SER 144 121 121 SER SER L . n E 3 145 SER 145 122 122 SER SER L . n E 3 146 GLU 146 123 123 GLU GLU L . n E 3 147 GLU 147 124 124 GLU GLU L . n E 3 148 LEU 148 125 125 LEU LEU L . n E 3 149 GLN 149 126 126 GLN GLN L . n E 3 150 ALA 150 127 127 ALA ALA L . n E 3 151 ASN 151 128 128 ASN ASN L . n E 3 152 LYS 152 129 129 LYS LYS L . n E 3 153 ALA 153 130 130 ALA ALA L . n E 3 154 THR 154 131 131 THR THR L . n E 3 155 LEU 155 132 132 LEU LEU L . n E 3 156 VAL 156 133 133 VAL VAL L . n E 3 157 CYS 157 134 134 CYS CYS L . n E 3 158 LEU 158 135 135 LEU LEU L . n E 3 159 ILE 159 136 136 ILE ILE L . n E 3 160 SER 160 137 137 SER SER L . n E 3 161 ASP 161 138 138 ASP ASP L . n E 3 162 PHE 162 139 139 PHE PHE L . n E 3 163 PHE 163 140 140 PHE PHE L . n E 3 164 PRO 164 141 141 PRO PRO L . n E 3 165 GLY 165 142 142 GLY GLY L . n E 3 166 ALA 166 143 143 ALA ALA L . n E 3 167 VAL 167 144 144 VAL VAL L . n E 3 168 THR 168 145 145 THR THR L . n E 3 169 VAL 169 146 146 VAL VAL L . n E 3 170 ALA 170 147 147 ALA ALA L . n E 3 171 TRP 171 148 148 TRP TRP L . n E 3 172 LYS 172 149 149 LYS LYS L . n E 3 173 ALA 173 150 150 ALA ALA L . n E 3 174 ASP 174 151 151 ASP ASP L . n E 3 175 GLY 175 152 152 GLY GLY L . n E 3 176 ALA 176 153 153 ALA ALA L . n E 3 177 PRO 177 154 154 PRO PRO L . n E 3 178 VAL 178 155 155 VAL VAL L . n E 3 179 LYS 179 156 156 LYS LYS L . n E 3 180 ALA 180 157 157 ALA ALA L . n E 3 181 GLY 181 158 158 GLY GLY L . n E 3 182 VAL 182 159 159 VAL VAL L . n E 3 183 GLU 183 160 160 GLU GLU L . n E 3 184 THR 184 161 161 THR THR L . n E 3 185 THR 185 162 162 THR THR L . n E 3 186 LYS 186 163 163 LYS LYS L . n E 3 187 PRO 187 164 164 PRO PRO L . n E 3 188 SER 188 165 165 SER SER L . n E 3 189 LYS 189 166 166 LYS LYS L . n E 3 190 GLN 190 167 167 GLN GLN L . n E 3 191 SER 191 168 168 SER SER L . n E 3 192 ASN 192 169 169 ASN ASN L . n E 3 193 ASN 193 170 170 ASN ASN L . n E 3 194 LYS 194 171 171 LYS LYS L . n E 3 195 TYR 195 172 172 TYR TYR L . n E 3 196 ALA 196 173 173 ALA ALA L . n E 3 197 ALA 197 174 174 ALA ALA L . n E 3 198 SER 198 175 175 SER SER L . n E 3 199 SER 199 176 176 SER SER L . n E 3 200 TYR 200 177 177 TYR TYR L . n E 3 201 LEU 201 178 178 LEU LEU L . n E 3 202 SER 202 179 179 SER SER L . n E 3 203 LEU 203 180 180 LEU LEU L . n E 3 204 THR 204 181 181 THR THR L . n E 3 205 PRO 205 182 182 PRO PRO L . n E 3 206 GLU 206 183 183 GLU GLU L . n E 3 207 GLN 207 184 184 GLN GLN L . n E 3 208 TRP 208 185 185 TRP TRP L . n E 3 209 LYS 209 186 186 LYS LYS L . n E 3 210 SER 210 187 187 SER SER L . n E 3 211 HIS 211 188 188 HIS HIS L . n E 3 212 ARG 212 189 189 ARG ARG L . n E 3 213 SER 213 190 190 SER SER L . n E 3 214 TYR 214 191 191 TYR TYR L . n E 3 215 SER 215 192 192 SER SER L . n E 3 216 CYS 216 193 193 CYS CYS L . n E 3 217 GLN 217 194 194 GLN GLN L . n E 3 218 VAL 218 195 195 VAL VAL L . n E 3 219 THR 219 196 196 THR THR L . n E 3 220 HIS 220 197 197 HIS HIS L . n E 3 221 GLU 221 198 198 GLU GLU L . n E 3 222 GLY 222 199 199 GLY GLY L . n E 3 223 SER 223 200 200 SER SER L . n E 3 224 THR 224 201 201 THR THR L . n E 3 225 VAL 225 202 202 VAL VAL L . n E 3 226 GLU 226 203 203 GLU GLU L . n E 3 227 LYS 227 204 204 LYS LYS L . n E 3 228 THR 228 205 205 THR THR L . n E 3 229 VAL 229 206 206 VAL VAL L . n E 3 230 ALA 230 207 207 ALA ALA L . n E 3 231 PRO 231 208 208 PRO PRO L . n E 3 232 THR 232 209 209 THR THR L . n E 3 233 GLU 233 210 210 GLU GLU L . n E 3 234 CYS 234 211 ? ? ? L . n F 3 1 MET 1 -18 ? ? ? M . n F 3 2 ALA 2 -17 ? ? ? M . n F 3 3 GLY 3 -16 ? ? ? M . n F 3 4 PHE 4 -15 ? ? ? M . n F 3 5 PRO 5 -14 ? ? ? M . n F 3 6 LEU 6 -13 ? ? ? M . n F 3 7 LEU 7 -12 ? ? ? M . n F 3 8 LEU 8 -11 ? ? ? M . n F 3 9 THR 9 -10 ? ? ? M . n F 3 10 LEU 10 -9 ? ? ? M . n F 3 11 LEU 11 -8 ? ? ? M . n F 3 12 THR 12 -7 ? ? ? M . n F 3 13 HIS 13 -6 ? ? ? M . n F 3 14 CYS 14 -5 ? ? ? M . n F 3 15 ALA 15 -4 ? ? ? M . n F 3 16 GLY 16 -3 ? ? ? M . n F 3 17 SER 17 -2 ? ? ? M . n F 3 18 TRP 18 -1 ? ? ? M . n F 3 19 ALA 19 0 ? ? ? M . n F 3 20 GLN 20 1 1 GLN GLN M . n F 3 21 SER 21 2 2 SER SER M . n F 3 22 VAL 22 3 3 VAL VAL M . n F 3 23 LEU 23 4 4 LEU LEU M . n F 3 24 THR 24 5 5 THR THR M . n F 3 25 GLN 25 6 6 GLN GLN M . n F 3 26 PRO 26 7 7 PRO PRO M . n F 3 27 PRO 27 8 8 PRO PRO M . n F 3 28 SER 28 9 9 SER SER M . n F 3 29 ALA 29 10 10 ALA ALA M . n F 3 30 SER 30 11 11 SER SER M . n F 3 31 GLY 31 12 12 GLY GLY M . n F 3 32 THR 32 13 13 THR THR M . n F 3 33 PRO 33 14 14 PRO PRO M . n F 3 34 GLY 34 15 15 GLY GLY M . n F 3 35 GLN 35 16 16 GLN GLN M . n F 3 36 ARG 36 17 17 ARG ARG M . n F 3 37 VAL 37 18 18 VAL VAL M . n F 3 38 THR 38 19 19 THR THR M . n F 3 39 ILE 39 20 20 ILE ILE M . n F 3 40 SER 40 21 21 SER SER M . n F 3 41 CYS 41 22 22 CYS CYS M . n F 3 42 SER 42 23 23 SER SER M . n F 3 43 GLY 43 24 24 GLY GLY M . n F 3 44 SER 44 25 25 SER SER M . n F 3 45 SER 45 26 26 SER SER M . n F 3 46 SER 46 27 27 SER SER M . n F 3 47 ASN 47 27 27 ASN ASN M A n F 3 48 ILE 48 28 28 ILE ILE M . n F 3 49 GLY 49 29 29 GLY GLY M . n F 3 50 SER 50 30 30 SER SER M . n F 3 51 ASN 51 31 31 ASN ASN M . n F 3 52 TYR 52 32 32 TYR TYR M . n F 3 53 VAL 53 33 33 VAL VAL M . n F 3 54 TYR 54 34 34 TYR TYR M . n F 3 55 TRP 55 35 35 TRP TRP M . n F 3 56 TYR 56 36 36 TYR TYR M . n F 3 57 GLN 57 37 37 GLN GLN M . n F 3 58 GLN 58 38 38 GLN GLN M . n F 3 59 LEU 59 39 39 LEU LEU M . n F 3 60 PRO 60 40 40 PRO PRO M . n F 3 61 GLY 61 41 41 GLY GLY M . n F 3 62 THR 62 42 42 THR THR M . n F 3 63 ALA 63 43 43 ALA ALA M . n F 3 64 PRO 64 44 44 PRO PRO M . n F 3 65 LYS 65 45 45 LYS LYS M . n F 3 66 LEU 66 46 46 LEU LEU M . n F 3 67 LEU 67 47 47 LEU LEU M . n F 3 68 ILE 68 48 48 ILE ILE M . n F 3 69 TYR 69 49 49 TYR TYR M . n F 3 70 ARG 70 50 50 ARG ARG M . n F 3 71 ASN 71 51 51 ASN ASN M . n F 3 72 ASN 72 52 52 ASN ASN M . n F 3 73 GLN 73 53 53 GLN GLN M . n F 3 74 ARG 74 54 54 ARG ARG M . n F 3 75 PRO 75 55 55 PRO PRO M . n F 3 76 SER 76 56 56 SER SER M . n F 3 77 GLY 77 57 57 GLY GLY M . n F 3 78 VAL 78 58 58 VAL VAL M . n F 3 79 PRO 79 59 59 PRO PRO M . n F 3 80 ASP 80 60 60 ASP ASP M . n F 3 81 ARG 81 61 61 ARG ARG M . n F 3 82 PHE 82 62 62 PHE PHE M . n F 3 83 SER 83 63 63 SER SER M . n F 3 84 GLY 84 64 64 GLY GLY M . n F 3 85 SER 85 65 65 SER SER M . n F 3 86 LYS 86 66 66 LYS LYS M . n F 3 87 SER 87 67 67 SER SER M . n F 3 88 GLY 88 68 68 GLY GLY M . n F 3 89 THR 89 69 69 THR THR M . n F 3 90 SER 90 70 70 SER SER M . n F 3 91 ALA 91 71 71 ALA ALA M . n F 3 92 SER 92 72 72 SER SER M . n F 3 93 LEU 93 73 73 LEU LEU M . n F 3 94 ALA 94 74 74 ALA ALA M . n F 3 95 ILE 95 75 75 ILE ILE M . n F 3 96 SER 96 76 76 SER SER M . n F 3 97 GLY 97 77 77 GLY GLY M . n F 3 98 LEU 98 78 78 LEU LEU M . n F 3 99 ARG 99 79 79 ARG ARG M . n F 3 100 SER 100 80 80 SER SER M . n F 3 101 GLU 101 81 81 GLU GLU M . n F 3 102 ASP 102 82 82 ASP ASP M . n F 3 103 GLU 103 83 83 GLU GLU M . n F 3 104 ALA 104 84 84 ALA ALA M . n F 3 105 ASP 105 85 85 ASP ASP M . n F 3 106 TYR 106 86 86 TYR TYR M . n F 3 107 TYR 107 87 87 TYR TYR M . n F 3 108 CYS 108 88 88 CYS CYS M . n F 3 109 ALA 109 89 89 ALA ALA M . n F 3 110 THR 110 90 90 THR THR M . n F 3 111 TRP 111 91 91 TRP TRP M . n F 3 112 ASP 112 92 92 ASP ASP M . n F 3 113 ASP 113 93 93 ASP ASP M . n F 3 114 SER 114 94 94 SER SER M . n F 3 115 LEU 115 95 95 LEU LEU M . n F 3 116 SER 116 95 95 SER SER M A n F 3 117 ALA 117 95 95 ALA ALA M B n F 3 118 VAL 118 96 96 VAL VAL M . n F 3 119 ILE 119 97 97 ILE ILE M . n F 3 120 PHE 120 98 98 PHE PHE M . n F 3 121 GLY 121 99 99 GLY GLY M . n F 3 122 GLY 122 100 100 GLY GLY M . n F 3 123 GLY 123 101 101 GLY GLY M . n F 3 124 THR 124 102 102 THR THR M . n F 3 125 LYS 125 103 103 LYS LYS M . n F 3 126 LEU 126 104 104 LEU LEU M . n F 3 127 THR 127 105 105 THR THR M . n F 3 128 VAL 128 106 106 VAL VAL M . n F 3 129 LEU 129 107 107 LEU LEU M . n F 3 130 GLY 130 108 108 GLY GLY M . n F 3 131 GLN 131 109 109 GLN GLN M . n F 3 132 PRO 132 110 110 PRO PRO M . n F 3 133 LYS 133 110 110 LYS LYS M A n F 3 134 ALA 134 111 111 ALA ALA M . n F 3 135 ALA 135 112 112 ALA ALA M . n F 3 136 PRO 136 113 113 PRO PRO M . n F 3 137 SER 137 114 114 SER SER M . n F 3 138 VAL 138 115 115 VAL VAL M . n F 3 139 THR 139 116 116 THR THR M . n F 3 140 LEU 140 117 117 LEU LEU M . n F 3 141 PHE 141 118 118 PHE PHE M . n F 3 142 PRO 142 119 119 PRO PRO M . n F 3 143 PRO 143 120 120 PRO PRO M . n F 3 144 SER 144 121 121 SER SER M . n F 3 145 SER 145 122 122 SER SER M . n F 3 146 GLU 146 123 123 GLU GLU M . n F 3 147 GLU 147 124 124 GLU GLU M . n F 3 148 LEU 148 125 125 LEU LEU M . n F 3 149 GLN 149 126 126 GLN GLN M . n F 3 150 ALA 150 127 127 ALA ALA M . n F 3 151 ASN 151 128 128 ASN ASN M . n F 3 152 LYS 152 129 129 LYS LYS M . n F 3 153 ALA 153 130 130 ALA ALA M . n F 3 154 THR 154 131 131 THR THR M . n F 3 155 LEU 155 132 132 LEU LEU M . n F 3 156 VAL 156 133 133 VAL VAL M . n F 3 157 CYS 157 134 134 CYS CYS M . n F 3 158 LEU 158 135 135 LEU LEU M . n F 3 159 ILE 159 136 136 ILE ILE M . n F 3 160 SER 160 137 137 SER SER M . n F 3 161 ASP 161 138 138 ASP ASP M . n F 3 162 PHE 162 139 139 PHE PHE M . n F 3 163 PHE 163 140 140 PHE PHE M . n F 3 164 PRO 164 141 141 PRO PRO M . n F 3 165 GLY 165 142 142 GLY GLY M . n F 3 166 ALA 166 143 143 ALA ALA M . n F 3 167 VAL 167 144 144 VAL VAL M . n F 3 168 THR 168 145 145 THR THR M . n F 3 169 VAL 169 146 146 VAL VAL M . n F 3 170 ALA 170 147 147 ALA ALA M . n F 3 171 TRP 171 148 148 TRP TRP M . n F 3 172 LYS 172 149 149 LYS LYS M . n F 3 173 ALA 173 150 150 ALA ALA M . n F 3 174 ASP 174 151 151 ASP ASP M . n F 3 175 GLY 175 152 152 GLY GLY M . n F 3 176 ALA 176 153 153 ALA ALA M . n F 3 177 PRO 177 154 154 PRO PRO M . n F 3 178 VAL 178 155 155 VAL VAL M . n F 3 179 LYS 179 156 156 LYS LYS M . n F 3 180 ALA 180 157 157 ALA ALA M . n F 3 181 GLY 181 158 158 GLY GLY M . n F 3 182 VAL 182 159 159 VAL VAL M . n F 3 183 GLU 183 160 160 GLU GLU M . n F 3 184 THR 184 161 161 THR THR M . n F 3 185 THR 185 162 162 THR THR M . n F 3 186 LYS 186 163 163 LYS LYS M . n F 3 187 PRO 187 164 164 PRO PRO M . n F 3 188 SER 188 165 165 SER SER M . n F 3 189 LYS 189 166 166 LYS LYS M . n F 3 190 GLN 190 167 167 GLN GLN M . n F 3 191 SER 191 168 168 SER SER M . n F 3 192 ASN 192 169 169 ASN ASN M . n F 3 193 ASN 193 170 170 ASN ASN M . n F 3 194 LYS 194 171 171 LYS LYS M . n F 3 195 TYR 195 172 172 TYR TYR M . n F 3 196 ALA 196 173 173 ALA ALA M . n F 3 197 ALA 197 174 174 ALA ALA M . n F 3 198 SER 198 175 175 SER SER M . n F 3 199 SER 199 176 176 SER SER M . n F 3 200 TYR 200 177 177 TYR TYR M . n F 3 201 LEU 201 178 178 LEU LEU M . n F 3 202 SER 202 179 179 SER SER M . n F 3 203 LEU 203 180 180 LEU LEU M . n F 3 204 THR 204 181 181 THR THR M . n F 3 205 PRO 205 182 182 PRO PRO M . n F 3 206 GLU 206 183 183 GLU GLU M . n F 3 207 GLN 207 184 184 GLN GLN M . n F 3 208 TRP 208 185 185 TRP TRP M . n F 3 209 LYS 209 186 186 LYS LYS M . n F 3 210 SER 210 187 187 SER SER M . n F 3 211 HIS 211 188 188 HIS HIS M . n F 3 212 ARG 212 189 189 ARG ARG M . n F 3 213 SER 213 190 190 SER SER M . n F 3 214 TYR 214 191 191 TYR TYR M . n F 3 215 SER 215 192 192 SER SER M . n F 3 216 CYS 216 193 193 CYS CYS M . n F 3 217 GLN 217 194 194 GLN GLN M . n F 3 218 VAL 218 195 195 VAL VAL M . n F 3 219 THR 219 196 196 THR THR M . n F 3 220 HIS 220 197 197 HIS HIS M . n F 3 221 GLU 221 198 198 GLU GLU M . n F 3 222 GLY 222 199 199 GLY GLY M . n F 3 223 SER 223 200 200 SER SER M . n F 3 224 THR 224 201 201 THR THR M . n F 3 225 VAL 225 202 202 VAL VAL M . n F 3 226 GLU 226 203 203 GLU GLU M . n F 3 227 LYS 227 204 204 LYS LYS M . n F 3 228 THR 228 205 205 THR THR M . n F 3 229 VAL 229 206 206 VAL VAL M . n F 3 230 ALA 230 207 207 ALA ALA M . n F 3 231 PRO 231 208 208 PRO PRO M . n F 3 232 THR 232 209 209 THR THR M . n F 3 233 GLU 233 210 210 GLU GLU M . n F 3 234 CYS 234 211 211 CYS CYS M . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code G 4 CD 1 1445 1445 CD CD A . H 5 ZN 1 1446 1446 ZN ZN A . I 6 CAC 1 1447 1447 CAC CAC A . J 7 MPD 1 1448 1448 MPD MPD A . K 7 MPD 1 1449 1449 MPD MPD A . L 7 MPD 1 1450 1450 MPD MPD A . M 8 ACT 1 1451 1451 ACT ACT A . N 8 ACT 1 1452 1452 ACT ACT A . O 9 NAG 1 1453 1453 NAG NAG A . P 10 FUL 2 1454 1454 FUL FUL A . Q 9 NAG 3 1455 1455 NAG NAG A . R 11 BMA 4 1456 1456 BMA BMA A . S 12 MAN 5 1457 1457 MAN MAN A . T 13 NDG 6 1458 1458 NDG NDG A . U 14 GAL 7 1459 1459 GAL GAL A . V 11 BMA 8 1460 1460 BMA BMA A . W 9 NAG 9 1461 1461 NAG NAG A . X 5 ZN 1 1446 1446 ZN ZN B . Y 7 MPD 1 1447 1447 MPD MPD B . Z 7 MPD 1 1448 1448 MPD MPD B . AA 8 ACT 1 1449 1449 ACT ACT B . BA 9 NAG 1 1450 1450 NAG NAG B . CA 10 FUL 2 1451 1451 FUL FUL B . DA 9 NAG 3 1452 1452 NAG NAG B . EA 11 BMA 4 1453 1453 BMA BMA B . FA 12 MAN 5 1454 1454 MAN MAN B . GA 9 NAG 6 1455 1455 NAG NAG B . HA 14 GAL 7 1456 1456 GAL GAL B . IA 11 BMA 8 1457 1457 BMA BMA B . JA 9 NAG 9 1458 1458 NAG NAG B . KA 8 ACT 1 1215 1215 ACT ACT H . LA 7 MPD 1 1212 1212 MPD MPD M . MA 15 HOH 1 2001 2001 HOH HOH A . MA 15 HOH 2 2002 2002 HOH HOH A . MA 15 HOH 3 2003 2003 HOH HOH A . MA 15 HOH 4 2004 2004 HOH HOH A . MA 15 HOH 5 2005 2005 HOH HOH A . MA 15 HOH 6 2006 2006 HOH HOH A . MA 15 HOH 7 2007 2007 HOH HOH A . MA 15 HOH 8 2008 2008 HOH HOH A . MA 15 HOH 9 2009 2009 HOH HOH A . MA 15 HOH 10 2010 2010 HOH HOH A . MA 15 HOH 11 2011 2011 HOH HOH A . MA 15 HOH 12 2012 2012 HOH HOH A . MA 15 HOH 13 2013 2013 HOH HOH A . MA 15 HOH 14 2014 2014 HOH HOH A . MA 15 HOH 15 2015 2015 HOH HOH A . MA 15 HOH 16 2016 2016 HOH HOH A . MA 15 HOH 17 2017 2017 HOH HOH A . MA 15 HOH 18 2018 2018 HOH HOH A . MA 15 HOH 19 2019 2019 HOH HOH A . MA 15 HOH 20 2020 2020 HOH HOH A . MA 15 HOH 21 2021 2021 HOH HOH A . MA 15 HOH 22 2022 2022 HOH HOH A . MA 15 HOH 23 2023 2023 HOH HOH A . MA 15 HOH 24 2024 2024 HOH HOH A . MA 15 HOH 25 2025 2025 HOH HOH A . MA 15 HOH 26 2026 2026 HOH HOH A . MA 15 HOH 27 2027 2027 HOH HOH A . MA 15 HOH 28 2028 2028 HOH HOH A . MA 15 HOH 29 2029 2029 HOH HOH A . MA 15 HOH 30 2030 2030 HOH HOH A . MA 15 HOH 31 2031 2031 HOH HOH A . MA 15 HOH 32 2032 2032 HOH HOH A . NA 15 HOH 1 2001 2001 HOH HOH B . NA 15 HOH 2 2002 2002 HOH HOH B . NA 15 HOH 3 2003 2003 HOH HOH B . NA 15 HOH 4 2004 2004 HOH HOH B . NA 15 HOH 5 2005 2005 HOH HOH B . NA 15 HOH 6 2006 2006 HOH HOH B . NA 15 HOH 7 2007 2007 HOH HOH B . NA 15 HOH 8 2008 2008 HOH HOH B . NA 15 HOH 9 2009 2009 HOH HOH B . NA 15 HOH 10 2010 2010 HOH HOH B . NA 15 HOH 11 2011 2011 HOH HOH B . NA 15 HOH 12 2012 2012 HOH HOH B . NA 15 HOH 13 2013 2013 HOH HOH B . NA 15 HOH 14 2014 2014 HOH HOH B . NA 15 HOH 15 2015 2015 HOH HOH B . NA 15 HOH 16 2016 2016 HOH HOH B . OA 15 HOH 1 2001 2001 HOH HOH H . OA 15 HOH 2 2002 2002 HOH HOH H . OA 15 HOH 3 2003 2003 HOH HOH H . OA 15 HOH 4 2004 2004 HOH HOH H . OA 15 HOH 5 2005 2005 HOH HOH H . OA 15 HOH 6 2006 2006 HOH HOH H . OA 15 HOH 7 2007 2007 HOH HOH H . OA 15 HOH 8 2008 2008 HOH HOH H . OA 15 HOH 9 2009 2009 HOH HOH H . PA 15 HOH 1 2001 2001 HOH HOH I . PA 15 HOH 2 2002 2002 HOH HOH I . PA 15 HOH 3 2003 2003 HOH HOH I . PA 15 HOH 4 2004 2004 HOH HOH I . PA 15 HOH 5 2005 2005 HOH HOH I . PA 15 HOH 6 2006 2006 HOH HOH I . PA 15 HOH 7 2007 2007 HOH HOH I . PA 15 HOH 8 2008 2008 HOH HOH I . PA 15 HOH 9 2009 2009 HOH HOH I . PA 15 HOH 10 2010 2010 HOH HOH I . PA 15 HOH 11 2011 2011 HOH HOH I . PA 15 HOH 12 2012 2012 HOH HOH I . PA 15 HOH 13 2013 2013 HOH HOH I . PA 15 HOH 14 2014 2014 HOH HOH I . PA 15 HOH 15 2015 2015 HOH HOH I . PA 15 HOH 16 2016 2016 HOH HOH I . PA 15 HOH 17 2017 2017 HOH HOH I . PA 15 HOH 18 2018 2018 HOH HOH I . PA 15 HOH 19 2019 2019 HOH HOH I . PA 15 HOH 20 2020 2020 HOH HOH I . QA 15 HOH 1 2001 2001 HOH HOH L . QA 15 HOH 2 2002 2002 HOH HOH L . QA 15 HOH 3 2003 2003 HOH HOH L . QA 15 HOH 4 2004 2004 HOH HOH L . RA 15 HOH 1 2001 2001 HOH HOH M . RA 15 HOH 2 2002 2002 HOH HOH M . RA 15 HOH 3 2003 2003 HOH HOH M . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 82 A ASN 297 ? ASN 'GLYCOSYLATION SITE' 2 B ASN 82 B ASN 297 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PQS _pdbx_struct_assembly.oligomeric_details hexameric _pdbx_struct_assembly.oligomeric_count 6 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,FA,GA,HA,IA,JA,KA,LA,MA,NA,OA,PA,QA,RA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 14400 ? 1 MORE -78.3 ? 1 'SSA (A^2)' 70770 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OE1 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 OE2 ? A GLU 79 ? A GLU 294 ? 4_546 50.4 ? 2 OE1 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 220 ? A HIS 435 ? 1_555 111.5 ? 3 OE2 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 220 ? A HIS 435 ? 1_555 150.4 ? 4 OE1 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 95 ? A HIS 310 ? 1_555 108.4 ? 5 OE2 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 95 ? A HIS 310 ? 1_555 96.0 ? 6 NE2 ? A HIS 220 ? A HIS 435 ? 1_555 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 95 ? A HIS 310 ? 1_555 113.1 ? 7 OE1 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 53 ? A HIS 268 ? 4_546 116.2 ? 8 OE2 ? A GLU 79 ? A GLU 294 ? 4_546 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 53 ? A HIS 268 ? 4_546 79.0 ? 9 NE2 ? A HIS 220 ? A HIS 435 ? 1_555 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 53 ? A HIS 268 ? 4_546 93.5 ? 10 NE2 ? A HIS 95 ? A HIS 310 ? 1_555 CD ? G CD . ? A CD 1445 ? 1_555 NE2 ? A HIS 53 ? A HIS 268 ? 4_546 113.6 ? 11 O1 ? I CAC . ? A CAC 1447 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE1 ? A GLU 130 ? A GLU 345 ? 1_555 102.1 ? 12 O1 ? I CAC . ? A CAC 1447 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE1 ? A GLU 57 ? A GLU 272 ? 4_546 101.8 ? 13 OE1 ? A GLU 130 ? A GLU 345 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE1 ? A GLU 57 ? A GLU 272 ? 4_546 118.1 ? 14 O1 ? I CAC . ? A CAC 1447 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 NE2 ? A HIS 218 ? A HIS 433 ? 1_555 141.6 ? 15 OE1 ? A GLU 130 ? A GLU 345 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 NE2 ? A HIS 218 ? A HIS 433 ? 1_555 91.1 ? 16 OE1 ? A GLU 57 ? A GLU 272 ? 4_546 ZN ? H ZN . ? A ZN 1446 ? 1_555 NE2 ? A HIS 218 ? A HIS 433 ? 1_555 103.3 ? 17 O1 ? I CAC . ? A CAC 1447 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 130 ? A GLU 345 ? 1_555 86.3 ? 18 OE1 ? A GLU 130 ? A GLU 345 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 130 ? A GLU 345 ? 1_555 56.0 ? 19 OE1 ? A GLU 57 ? A GLU 272 ? 4_546 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 130 ? A GLU 345 ? 1_555 69.7 ? 20 NE2 ? A HIS 218 ? A HIS 433 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 130 ? A GLU 345 ? 1_555 129.7 ? 21 O1 ? I CAC . ? A CAC 1447 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 57 ? A GLU 272 ? 4_546 80.3 ? 22 OE1 ? A GLU 130 ? A GLU 345 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 57 ? A GLU 272 ? 4_546 174.0 ? 23 OE1 ? A GLU 57 ? A GLU 272 ? 4_546 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 57 ? A GLU 272 ? 4_546 66.3 ? 24 NE2 ? A HIS 218 ? A HIS 433 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 57 ? A GLU 272 ? 4_546 83.7 ? 25 OE2 ? A GLU 130 ? A GLU 345 ? 1_555 ZN ? H ZN . ? A ZN 1446 ? 1_555 OE2 ? A GLU 57 ? A GLU 272 ? 4_546 129.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2007-04-10 2 'Structure model' 1 1 2011-05-08 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.1 ? 1 DENZO 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 AMoRE phasing . ? 4 # _pdbx_database_remark.id 700 _pdbx_database_remark.text ; SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED. ; # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 N _pdbx_validate_close_contact.auth_asym_id_1 H _pdbx_validate_close_contact.auth_comp_id_1 GLY _pdbx_validate_close_contact.auth_seq_id_1 96 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 O _pdbx_validate_close_contact.auth_asym_id_2 H _pdbx_validate_close_contact.auth_comp_id_2 GLY _pdbx_validate_close_contact.auth_seq_id_2 100 _pdbx_validate_close_contact.PDB_ins_code_2 D _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.16 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA H CYS 92 ? ? CB H CYS 92 ? ? SG H CYS 92 ? ? 120.86 114.20 6.66 1.10 N 2 1 CA I CYS 92 ? ? CB I CYS 92 ? ? SG I CYS 92 ? ? 123.11 114.20 8.91 1.10 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ILE A 253 ? ? -37.90 -31.81 2 1 ASP A 265 ? ? 72.06 40.64 3 1 ASN A 297 ? ? -95.37 38.15 4 1 SER A 337 ? ? 167.04 158.63 5 1 LYS A 338 ? ? -47.79 152.05 6 1 PRO A 352 ? ? -57.93 170.07 7 1 ASN A 384 ? ? 25.68 47.54 8 1 PRO A 387 ? ? -71.72 -164.23 9 1 LYS A 414 ? ? -37.79 -39.71 10 1 GLU B 258 ? ? -171.60 143.95 11 1 ASP B 265 ? ? 63.58 77.64 12 1 SER B 267 ? ? -53.14 170.49 13 1 GLU B 269 ? ? -54.68 -78.50 14 1 GLU B 272 ? ? -37.33 120.06 15 1 VAL B 282 ? ? -46.23 155.24 16 1 ASN B 286 ? ? 177.70 88.69 17 1 ALA B 287 ? ? -153.33 81.95 18 1 LYS B 288 ? ? -36.95 147.85 19 1 GLU B 293 ? ? -57.20 108.38 20 1 ASN B 297 ? ? -156.09 57.16 21 1 HIS B 310 ? ? -37.14 -77.09 22 1 ASN B 315 ? ? -103.52 70.14 23 1 ALA B 327 ? ? -67.40 26.35 24 1 ALA B 330 ? ? -110.01 73.98 25 1 PRO B 331 ? ? -29.92 100.31 26 1 ILE B 332 ? ? -38.90 138.45 27 1 GLN B 342 ? ? -48.31 108.06 28 1 TYR B 436 ? ? -170.99 130.98 29 1 SER B 442 ? ? -175.84 148.74 30 1 PRO B 445 ? ? -56.71 103.56 31 1 PRO H 14 ? ? -37.92 151.16 32 1 SER H 15 ? ? 64.61 -17.42 33 1 GLU H 16 ? ? -67.90 -165.14 34 1 PRO H 41 ? ? -24.52 -56.52 35 1 LYS H 43 ? ? -57.13 -163.45 36 1 ASN H 56 ? ? -37.84 121.23 37 1 LEU H 63 ? ? -151.47 27.83 38 1 THR H 83 ? ? -124.02 -158.81 39 1 ASP H 86 ? ? -57.38 28.66 40 1 ALA H 88 ? ? -167.18 -168.33 41 1 SER H 113 ? ? -147.06 -8.44 42 1 SER H 115 ? ? 85.80 146.63 43 1 ALA H 116 ? ? -56.00 178.40 44 1 SER H 117 ? ? 177.30 134.89 45 1 SER H 135 ? ? 74.40 68.17 46 1 LEU H 141 ? ? -50.23 174.59 47 1 ALA H 142 ? ? -178.22 116.54 48 1 GLN H 143 ? ? -115.51 -160.14 49 1 ASP H 144 ? ? 80.94 -58.58 50 1 LEU H 146 ? ? -102.91 -64.29 51 1 SER H 149 ? ? 164.62 70.51 52 1 THR H 151 ? ? -66.31 78.87 53 1 SER H 153 ? ? 173.45 174.47 54 1 TYR H 156 ? ? -58.24 -163.73 55 1 LYS H 157 ? ? -60.78 -78.20 56 1 ASN H 158 ? ? -71.42 40.39 57 1 ASN H 159 ? ? 54.99 78.15 58 1 SER H 163 ? ? -65.39 16.62 59 1 ALA H 178 ? ? -175.69 111.49 60 1 THR H 180 ? ? -101.85 -155.43 61 1 SER H 181 ? ? 169.57 104.21 62 1 PRO H 186 ? ? -55.38 -133.57 63 1 LYS H 188 ? ? 146.27 66.64 64 1 ASP H 189 ? ? -143.13 -71.99 65 1 VAL H 190 ? ? 42.60 -155.37 66 1 THR H 194 ? ? -63.30 -102.15 67 1 ASP H 195 ? ? -166.17 -16.38 68 1 HIS H 197 ? ? 43.08 -170.97 69 1 HIS H 204 ? ? 172.57 142.38 70 1 SER I 15 ? ? 72.12 -23.13 71 1 PRO I 41 ? ? -23.92 -64.61 72 1 LEU I 63 ? ? -166.90 26.29 73 1 ALA I 84 ? ? -36.87 -30.77 74 1 ALA I 88 ? ? -173.25 -169.55 75 1 SER I 115 ? ? 52.17 156.17 76 1 ALA I 116 ? ? -42.70 164.23 77 1 SER I 117 ? ? -178.20 -169.39 78 1 VAL I 125 ? ? -53.05 -115.22 79 1 SER I 126 ? ? -172.47 -35.47 80 1 SER I 134 ? ? -68.69 85.12 81 1 SER I 135 ? ? 79.46 97.67 82 1 ASP I 144 ? ? 64.89 -16.77 83 1 LEU I 146 ? ? -99.87 -95.19 84 1 SER I 149 ? ? -168.60 19.77 85 1 ILE I 150 ? ? -55.45 173.58 86 1 THR I 151 ? ? -165.59 99.43 87 1 TYR I 156 ? ? -68.38 -161.52 88 1 ASN I 159 ? ? 28.93 41.42 89 1 PRO I 186 ? ? -49.56 -70.99 90 1 SER I 187 ? ? -172.99 -52.95 91 1 LYS I 188 ? ? -166.52 18.53 92 1 ASP I 189 ? ? -73.26 -121.69 93 1 VAL I 190 ? ? 37.88 -125.75 94 1 MET I 191 ? ? -135.21 -81.48 95 1 THR I 194 ? ? -57.76 -129.74 96 1 ASP I 195 ? ? -154.53 44.26 97 1 HIS I 197 ? ? 25.06 -174.01 98 1 HIS I 204 ? ? 178.23 139.06 99 1 ASN I 206 ? ? -86.00 48.97 100 1 ALA L 10 ? ? -138.74 -74.39 101 1 SER L 11 ? ? 63.05 143.21 102 1 PRO L 14 ? ? -33.82 153.40 103 1 GLN L 16 ? ? -72.26 -160.57 104 1 ASN L 27 A ? -143.87 -100.13 105 1 ILE L 28 ? ? -52.46 -9.40 106 1 PRO L 40 ? ? -19.10 121.78 107 1 ASN L 51 ? ? 74.06 -49.62 108 1 ASN L 52 ? ? -152.97 29.21 109 1 SER L 56 ? ? -35.18 106.93 110 1 SER L 67 ? ? -177.11 128.36 111 1 LEU L 78 ? ? -39.14 148.18 112 1 GLU L 81 ? ? -72.90 24.59 113 1 LYS L 103 ? ? -64.66 -75.60 114 1 LEU L 104 ? ? 65.17 113.88 115 1 GLN L 109 ? ? 33.87 74.07 116 1 PRO L 120 ? ? -44.95 168.07 117 1 GLN L 126 ? ? -77.52 32.33 118 1 ALA L 127 ? ? -169.39 32.26 119 1 ASN L 128 ? ? 41.98 72.10 120 1 LYS L 129 ? ? -163.69 105.39 121 1 SER L 137 ? ? -68.06 -125.04 122 1 PHE L 139 ? ? 172.18 119.51 123 1 ALA L 143 ? ? -173.83 119.75 124 1 THR L 145 ? ? -106.29 68.88 125 1 ASP L 151 ? ? 70.12 -67.15 126 1 LYS L 156 ? ? -48.42 -98.31 127 1 ALA L 157 ? ? -117.83 -153.90 128 1 THR L 162 ? ? -82.54 -152.74 129 1 PRO L 164 ? ? -55.58 171.86 130 1 SER L 165 ? ? -167.90 111.02 131 1 SER L 179 ? ? -85.59 -111.53 132 1 LEU L 180 ? ? 63.36 121.71 133 1 THR L 181 ? ? -39.40 147.72 134 1 GLU L 183 ? ? -84.07 32.93 135 1 SER L 190 ? ? 60.94 123.04 136 1 SER L 200 ? ? -56.58 106.81 137 1 THR L 201 ? ? -97.94 55.20 138 1 PRO L 208 ? ? -64.03 12.92 139 1 THR L 209 ? ? -140.12 -67.39 140 1 SER M 2 ? ? -141.78 21.25 141 1 ALA M 10 ? ? -139.12 -117.87 142 1 SER M 11 ? ? 70.38 134.82 143 1 GLN M 16 ? ? -49.87 160.00 144 1 ASN M 27 A ? -131.31 -102.86 145 1 ILE M 28 ? ? -49.14 -17.27 146 1 PRO M 44 ? ? -45.96 157.89 147 1 ASN M 51 ? ? 65.30 -52.94 148 1 ASN M 52 ? ? -156.12 42.42 149 1 SER M 63 ? ? -174.28 142.60 150 1 SER M 65 ? ? -170.80 141.53 151 1 SER M 67 ? ? 179.60 130.35 152 1 THR M 69 ? ? -145.73 38.69 153 1 LEU M 78 ? ? -30.42 138.10 154 1 GLU M 81 ? ? -76.73 32.09 155 1 ALA M 84 ? ? 177.90 -173.82 156 1 SER M 95 A ? 73.72 46.55 157 1 PRO M 110 ? ? -76.58 41.65 158 1 ALA M 112 ? ? -108.78 58.93 159 1 PRO M 113 ? ? -55.30 73.43 160 1 SER M 114 ? ? -66.56 75.52 161 1 ALA M 127 ? ? -64.09 16.74 162 1 ASN M 128 ? ? 72.97 30.72 163 1 ALA M 130 ? ? -157.65 49.06 164 1 ILE M 136 ? ? -66.13 95.36 165 1 SER M 137 ? ? -53.48 -140.41 166 1 PHE M 139 ? ? -167.90 -161.89 167 1 PHE M 140 ? ? 178.07 136.25 168 1 ALA M 143 ? ? 169.37 131.12 169 1 VAL M 144 ? ? -151.04 -155.95 170 1 ALA M 147 ? ? -165.39 114.72 171 1 ASP M 151 ? ? 76.52 -82.81 172 1 LYS M 156 ? ? -63.81 -136.03 173 1 ALA M 157 ? ? -53.71 -163.66 174 1 VAL M 159 ? ? -108.62 60.92 175 1 GLN M 167 ? ? -119.75 -168.05 176 1 SER M 179 ? ? -57.79 -106.19 177 1 LEU M 180 ? ? 64.56 133.26 178 1 LYS M 186 ? ? -57.73 -5.68 179 1 SER M 187 ? ? -99.18 -85.25 180 1 HIS M 188 ? ? -38.19 168.84 181 1 SER M 190 ? ? 63.63 139.57 182 1 GLU M 198 ? ? 46.04 74.42 183 1 THR M 201 ? ? -91.51 57.87 184 1 PRO M 208 ? ? -67.86 14.61 185 1 GLU M 210 ? ? -85.81 43.85 # _pdbx_validate_polymer_linkage.id 1 _pdbx_validate_polymer_linkage.PDB_model_num 1 _pdbx_validate_polymer_linkage.auth_atom_id_1 C _pdbx_validate_polymer_linkage.auth_asym_id_1 I _pdbx_validate_polymer_linkage.auth_comp_id_1 CYS _pdbx_validate_polymer_linkage.auth_seq_id_1 127 _pdbx_validate_polymer_linkage.PDB_ins_code_1 ? _pdbx_validate_polymer_linkage.label_alt_id_1 ? _pdbx_validate_polymer_linkage.auth_atom_id_2 N _pdbx_validate_polymer_linkage.auth_asym_id_2 I _pdbx_validate_polymer_linkage.auth_comp_id_2 ASP _pdbx_validate_polymer_linkage.auth_seq_id_2 132 _pdbx_validate_polymer_linkage.PDB_ins_code_2 ? _pdbx_validate_polymer_linkage.label_alt_id_2 ? _pdbx_validate_polymer_linkage.dist 15.42 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A PRO 445 ? CA ? A PRO 230 CA 2 1 Y 1 A PRO 445 ? C ? A PRO 230 C 3 1 Y 1 A PRO 445 ? O ? A PRO 230 O 4 1 Y 1 A PRO 445 ? CB ? A PRO 230 CB 5 1 Y 1 A PRO 445 ? CG ? A PRO 230 CG 6 1 Y 1 A PRO 445 ? CD ? A PRO 230 CD 7 1 Y 1 B PRO 238 ? CG ? B PRO 23 CG 8 1 Y 1 B PRO 238 ? CD ? B PRO 23 CD 9 1 Y 1 B GLY 446 ? CA ? B GLY 231 CA 10 1 Y 1 B GLY 446 ? C ? B GLY 231 C 11 1 Y 1 B GLY 446 ? O ? B GLY 231 O 12 1 Y 1 L GLU 210 ? CA ? E GLU 233 CA 13 1 Y 1 L GLU 210 ? C ? E GLU 233 C 14 1 Y 1 L GLU 210 ? O ? E GLU 233 O 15 1 Y 1 L GLU 210 ? CB ? E GLU 233 CB 16 1 Y 1 L GLU 210 ? CG ? E GLU 233 CG 17 1 Y 1 L GLU 210 ? CD ? E GLU 233 CD 18 1 Y 1 L GLU 210 ? OE1 ? E GLU 233 OE1 19 1 Y 1 L GLU 210 ? OE2 ? E GLU 233 OE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 216 ? A GLU 1 2 1 Y 1 A PRO 217 ? A PRO 2 3 1 Y 1 A LYS 218 ? A LYS 3 4 1 Y 1 A SER 219 ? A SER 4 5 1 Y 1 A CYS 220 ? A CYS 5 6 1 Y 1 A ASP 221 ? A ASP 6 7 1 Y 1 A LYS 222 ? A LYS 7 8 1 Y 1 A THR 223 ? A THR 8 9 1 Y 1 A HIS 224 ? A HIS 9 10 1 Y 1 A THR 225 ? A THR 10 11 1 Y 1 A CYS 226 ? A CYS 11 12 1 Y 1 A PRO 227 ? A PRO 12 13 1 Y 1 A PRO 228 ? A PRO 13 14 1 Y 1 A CYS 229 ? A CYS 14 15 1 Y 1 A PRO 230 ? A PRO 15 16 1 Y 1 A ALA 231 ? A ALA 16 17 1 Y 1 A PRO 232 ? A PRO 17 18 1 Y 1 A GLU 233 ? A GLU 18 19 1 Y 1 A LEU 234 ? A LEU 19 20 1 Y 1 A LEU 235 ? A LEU 20 21 1 Y 1 A GLY 446 ? A GLY 231 22 1 Y 1 A LYS 447 ? A LYS 232 23 1 Y 1 B GLU 216 ? B GLU 1 24 1 Y 1 B PRO 217 ? B PRO 2 25 1 Y 1 B LYS 218 ? B LYS 3 26 1 Y 1 B SER 219 ? B SER 4 27 1 Y 1 B CYS 220 ? B CYS 5 28 1 Y 1 B ASP 221 ? B ASP 6 29 1 Y 1 B LYS 222 ? B LYS 7 30 1 Y 1 B THR 223 ? B THR 8 31 1 Y 1 B HIS 224 ? B HIS 9 32 1 Y 1 B THR 225 ? B THR 10 33 1 Y 1 B CYS 226 ? B CYS 11 34 1 Y 1 B PRO 227 ? B PRO 12 35 1 Y 1 B PRO 228 ? B PRO 13 36 1 Y 1 B CYS 229 ? B CYS 14 37 1 Y 1 B PRO 230 ? B PRO 15 38 1 Y 1 B ALA 231 ? B ALA 16 39 1 Y 1 B PRO 232 ? B PRO 17 40 1 Y 1 B GLU 233 ? B GLU 18 41 1 Y 1 B LEU 234 ? B LEU 19 42 1 Y 1 B LEU 235 ? B LEU 20 43 1 Y 1 B GLY 236 ? B GLY 21 44 1 Y 1 B GLY 237 ? B GLY 22 45 1 Y 1 B LYS 447 ? B LYS 232 46 1 Y 1 H LEU -10 ? C LEU 1 47 1 Y 1 H LEU -9 ? C LEU 2 48 1 Y 1 H LEU -8 ? C LEU 3 49 1 Y 1 H VAL -7 ? C VAL 4 50 1 Y 1 H ALA -6 ? C ALA 5 51 1 Y 1 H ALA -5 ? C ALA 6 52 1 Y 1 H PRO -4 ? C PRO 7 53 1 Y 1 H ARG -3 ? C ARG 8 54 1 Y 1 H TRP -2 ? C TRP 9 55 1 Y 1 H LEU -1 ? C LEU 10 56 1 Y 1 H SER 0 ? C SER 11 57 1 Y 1 H SER 130 ? C SER 147 58 1 Y 1 H CYS 131 ? C CYS 148 59 1 Y 1 H ASP 132 ? C ASP 149 60 1 Y 1 H THR 133 ? C THR 150 61 1 Y 1 I LEU -10 ? D LEU 1 62 1 Y 1 I LEU -9 ? D LEU 2 63 1 Y 1 I LEU -8 ? D LEU 3 64 1 Y 1 I VAL -7 ? D VAL 4 65 1 Y 1 I ALA -6 ? D ALA 5 66 1 Y 1 I ALA -5 ? D ALA 6 67 1 Y 1 I PRO -4 ? D PRO 7 68 1 Y 1 I ARG -3 ? D ARG 8 69 1 Y 1 I TRP -2 ? D TRP 9 70 1 Y 1 I LEU -1 ? D LEU 10 71 1 Y 1 I SER 0 ? D SER 11 72 1 Y 1 L MET -18 ? E MET 1 73 1 Y 1 L ALA -17 ? E ALA 2 74 1 Y 1 L GLY -16 ? E GLY 3 75 1 Y 1 L PHE -15 ? E PHE 4 76 1 Y 1 L PRO -14 ? E PRO 5 77 1 Y 1 L LEU -13 ? E LEU 6 78 1 Y 1 L LEU -12 ? E LEU 7 79 1 Y 1 L LEU -11 ? E LEU 8 80 1 Y 1 L THR -10 ? E THR 9 81 1 Y 1 L LEU -9 ? E LEU 10 82 1 Y 1 L LEU -8 ? E LEU 11 83 1 Y 1 L THR -7 ? E THR 12 84 1 Y 1 L HIS -6 ? E HIS 13 85 1 Y 1 L CYS -5 ? E CYS 14 86 1 Y 1 L ALA -4 ? E ALA 15 87 1 Y 1 L GLY -3 ? E GLY 16 88 1 Y 1 L SER -2 ? E SER 17 89 1 Y 1 L TRP -1 ? E TRP 18 90 1 Y 1 L ALA 0 ? E ALA 19 91 1 Y 1 L CYS 211 ? E CYS 234 92 1 Y 1 M MET -18 ? F MET 1 93 1 Y 1 M ALA -17 ? F ALA 2 94 1 Y 1 M GLY -16 ? F GLY 3 95 1 Y 1 M PHE -15 ? F PHE 4 96 1 Y 1 M PRO -14 ? F PRO 5 97 1 Y 1 M LEU -13 ? F LEU 6 98 1 Y 1 M LEU -12 ? F LEU 7 99 1 Y 1 M LEU -11 ? F LEU 8 100 1 Y 1 M THR -10 ? F THR 9 101 1 Y 1 M LEU -9 ? F LEU 10 102 1 Y 1 M LEU -8 ? F LEU 11 103 1 Y 1 M THR -7 ? F THR 12 104 1 Y 1 M HIS -6 ? F HIS 13 105 1 Y 1 M CYS -5 ? F CYS 14 106 1 Y 1 M ALA -4 ? F ALA 15 107 1 Y 1 M GLY -3 ? F GLY 16 108 1 Y 1 M SER -2 ? F SER 17 109 1 Y 1 M TRP -1 ? F TRP 18 110 1 Y 1 M ALA 0 ? F ALA 19 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 'CADMIUM ION' CD 5 'ZINC ION' ZN 6 'CACODYLATE ION' CAC 7 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 8 'ACETATE ION' ACT 9 N-ACETYL-D-GLUCOSAMINE NAG 10 BETA-L-FUCOSE FUL 11 BETA-D-MANNOSE BMA 12 ALPHA-D-MANNOSE MAN 13 '2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE' NDG 14 BETA-D-GALACTOSE GAL 15 water HOH #