data_2F1A # _entry.id 2F1A # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2F1A RCSB RCSB035327 WWPDB D_1000035327 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY . unspecified PDB 1HWW . unspecified PDB 1HXK . unspecified PDB 1PS2 . unspecified PDB 1QWN . unspecified PDB 1QX1 . unspecified PDB 1R33 . unspecified PDB 1R34 . unspecified PDB 1TQS . unspecified PDB 1TQT . unspecified PDB 1TQU . unspecified PDB 1TQW . unspecified PDB 2ALW . unspecified PDB 2F18 . unspecified PDB 2F1B . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2F1A _pdbx_database_status.recvd_initial_deposition_date 2005-11-14 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title 'Evaluation of docking programs for predicting binding of Golgi alpha-mannosidase II inhibitors: a comparison with crystallography.' _citation.journal_abbrev Proteins _citation.journal_volume 69 _citation.page_first 160 _citation.page_last 176 _citation.year 2007 _citation.journal_id_ASTM PSFGEY _citation.country US _citation.journal_id_ISSN 0887-3585 _citation.journal_id_CSD 0867 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 17557336 _citation.pdbx_database_id_DOI 10.1002/prot.21479 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Englebienne, P.' 1 primary 'Fiaux, H.' 2 primary 'Kuntz, D.A.' 3 primary 'Corbeil, C.R.' 4 primary 'Gerber-Lemaire, S.' 5 primary 'Rose, D.R.' 6 primary 'Moitessier, N.' 7 # _cell.entry_id 2F1A _cell.length_a 68.904 _cell.length_b 109.360 _cell.length_c 138.585 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2F1A _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'alpha-mannosidase II' 119701.617 1 3.2.1.114 ? 'CATALYTIC DOMAIN' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'PHOSPHATE ION' 94.971 1 ? ? ? ? 4 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 5 non-polymer syn '(2R,3R,4S)-2-({[(1S)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' 252.309 1 ? ? ? ? 6 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 1 ? ? ? ? 7 water nat water 18.015 1099 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name GB _struct_ref.db_code CAA54732 _struct_ref.pdbx_db_accession 517481 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2F1A _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession 517481 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2F1A ARG A 1 ? GB 517481 ? ? 'EXPRESSION TAG' 1 1 1 2F1A SER A 2 ? GB 517481 ? ? 'EXPRESSION TAG' 2 2 1 2F1A SER A 3 ? GB 517481 ? ? 'EXPRESSION TAG' 3 3 1 2F1A HIS A 4 ? GB 517481 ? ? 'EXPRESSION TAG' 4 4 1 2F1A HIS A 5 ? GB 517481 ? ? 'EXPRESSION TAG' 5 5 1 2F1A HIS A 6 ? GB 517481 ? ? 'EXPRESSION TAG' 6 6 1 2F1A HIS A 7 ? GB 517481 ? ? 'EXPRESSION TAG' 7 7 1 2F1A HIS A 8 ? GB 517481 ? ? 'EXPRESSION TAG' 8 8 1 2F1A HIS A 9 ? GB 517481 ? ? 'EXPRESSION TAG' 9 9 1 2F1A GLY A 10 ? GB 517481 ? ? 'EXPRESSION TAG' 10 10 1 2F1A GLU A 11 ? GB 517481 ? ? 'EXPRESSION TAG' 11 11 1 2F1A PHE A 12 ? GB 517481 ? ? 'EXPRESSION TAG' 12 12 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GB2 non-polymer . '(2R,3R,4S)-2-({[(1S)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' ? 'C13 H20 N2 O3' 252.309 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PO4 non-polymer . 'PHOSPHATE ION' ? 'O4 P -3' 94.971 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2F1A _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 2 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.18 _exptl_crystal.density_percent_sol 43.57 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details 'Tris, PEG 6K, MPD, NaCl, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2004-12-10 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9793376 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'APS BEAMLINE 19-ID' _diffrn_source.pdbx_synchrotron_site APS _diffrn_source.pdbx_synchrotron_beamline 19-ID _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9793376 # _reflns.entry_id 2F1A _reflns.observed_criterion_sigma_I 2 _reflns.observed_criterion_sigma_F 2 _reflns.d_resolution_low 30 _reflns.d_resolution_high 1.45 _reflns.number_obs 180243 _reflns.number_all 187133 _reflns.percent_possible_obs 96.3 _reflns.pdbx_Rmerge_I_obs 0.06 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 18.5 _reflns.B_iso_Wilson_estimate 18.4 _reflns.pdbx_redundancy 12.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.45 _reflns_shell.d_res_low 1.50 _reflns_shell.percent_possible_all 88 _reflns_shell.Rmerge_I_obs 0.57 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 3.72 _reflns_shell.pdbx_redundancy 10 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 17773 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2F1A _refine.ls_number_reflns_obs 174398 _refine.ls_number_reflns_all 185304 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 2 _refine.pdbx_data_cutoff_high_absF 96240.67 _refine.pdbx_data_cutoff_low_absF 0.000000 _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 29.78 _refine.ls_d_res_high 1.45 _refine.ls_percent_reflns_obs 93.9 _refine.ls_R_factor_obs 0.168 _refine.ls_R_factor_all 0.169 _refine.ls_R_factor_R_work 0.168 _refine.ls_R_factor_R_free 0.189 _refine.ls_R_factor_R_free_error 0.003 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 2.3 _refine.ls_number_reflns_R_free 3983 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 21.5 _refine.aniso_B[1][1] -1.42 _refine.aniso_B[2][2] 0.75 _refine.aniso_B[3][3] 0.67 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.332052 _refine.solvent_model_param_bsol 43.9683 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 'pdb entry 1HWW' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_overall_phase_error ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 2F1A _refine_analyze.Luzzati_coordinate_error_obs 0.14 _refine_analyze.Luzzati_sigma_a_obs 0.10 _refine_analyze.Luzzati_d_res_low_obs 30.00 _refine_analyze.Luzzati_coordinate_error_free 0.17 _refine_analyze.Luzzati_sigma_a_free 0.12 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8188 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 46 _refine_hist.number_atoms_solvent 1099 _refine_hist.number_atoms_total 9333 _refine_hist.d_res_high 1.45 _refine_hist.d_res_low 29.78 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.015 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.7 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 25.1 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.18 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 1.30 1.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 2.05 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 2.46 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 3.73 2.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 1.45 _refine_ls_shell.d_res_low 1.54 _refine_ls_shell.number_reflns_R_work 24945 _refine_ls_shell.R_factor_R_work 0.226 _refine_ls_shell.percent_reflns_obs 83.2 _refine_ls_shell.R_factor_R_free 0.263 _refine_ls_shell.R_factor_R_free_error 0.012 _refine_ls_shell.percent_reflns_R_free 2.1 _refine_ls_shell.number_reflns_R_free 524 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein_rep.top 'X-RAY DIFFRACTION' 2 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' 3 cis_peptide.param cis_peptide.top 'X-RAY DIFFRACTION' 4 water_rep.param water_rep.top 'X-RAY DIFFRACTION' 5 GB2.par ion.top 'X-RAY DIFFRACTION' 6 ? po4.top 'X-RAY DIFFRACTION' 7 ? GB2.top 'X-RAY DIFFRACTION' # _struct.entry_id 2F1A _struct.title 'GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S)-2-({[(1S)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' _struct.pdbx_descriptor 'alpha-mannosidase II (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2F1A _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'GLYCOSYL HYDROLASE FAMILY 38, Hydrolase' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? G N N 7 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.048 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.036 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.088 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.068 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.008 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 1802 1_555 ? ? ? ? ? ? ? 1.446 ? metalc1 metalc ? ? A HIS 90 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 90 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.107 ? metalc2 metalc ? ? A ASP 92 OD1 ? ? ? 1_555 D ZN . ZN ? ? A ASP 92 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.156 ? metalc3 metalc ? ? A ASP 204 OD2 ? ? ? 1_555 D ZN . ZN ? ? A ASP 204 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.079 ? metalc4 metalc ? ? A HIS 471 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 471 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.091 ? metalc5 metalc ? ? D ZN . ZN ? ? ? 1_555 E GB2 . O3 ? ? A ZN 1805 A GB2 1804 1_555 ? ? ? ? ? ? ? 2.199 ? metalc6 metalc ? ? D ZN . ZN ? ? ? 1_555 E GB2 . O4 ? ? A ZN 1805 A GB2 1804 1_555 ? ? ? ? ? ? ? 2.349 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -1.27 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 0.21 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 K 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O ASN A 223 ? O ASN A 223 N SER A 200 ? N SER A 200 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N PHE A 571 ? N PHE A 571 O ILE A 618 ? O ILE A 618 G 3 4 O ARG A 617 ? O ARG A 617 N SER A 593 ? N SER A 593 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 J 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 J 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 K 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 1802' AC2 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE PO4 A 1803' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 1805' AC4 Software ? ? ? ? 16 'BINDING SITE FOR RESIDUE GB2 A 1804' AC5 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE MPD A 1801' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 ASN A 194 ? ASN A 194 . ? 1_555 ? 2 AC2 9 ARG A 770 ? ARG A 770 . ? 1_555 ? 3 AC2 9 ARG A 893 ? ARG A 893 . ? 1_555 ? 4 AC2 9 SER A 924 ? SER A 924 . ? 1_555 ? 5 AC2 9 HOH G . ? HOH A 2619 . ? 1_555 ? 6 AC2 9 HOH G . ? HOH A 2620 . ? 1_555 ? 7 AC2 9 HOH G . ? HOH A 2694 . ? 1_555 ? 8 AC2 9 HOH G . ? HOH A 2696 . ? 1_555 ? 9 AC2 9 HOH G . ? HOH A 2697 . ? 1_555 ? 10 AC2 9 HOH G . ? HOH A 2699 . ? 1_555 ? 11 AC3 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 12 AC3 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 13 AC3 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 14 AC3 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 15 AC3 5 GB2 E . ? GB2 A 1804 . ? 1_555 ? 16 AC4 16 HIS A 90 ? HIS A 90 . ? 1_555 ? 17 AC4 16 ASP A 92 ? ASP A 92 . ? 1_555 ? 18 AC4 16 TRP A 95 ? TRP A 95 . ? 1_555 ? 19 AC4 16 ASP A 204 ? ASP A 204 . ? 1_555 ? 20 AC4 16 TYR A 269 ? TYR A 269 . ? 1_555 ? 21 AC4 16 ASP A 341 ? ASP A 341 . ? 1_555 ? 22 AC4 16 HIS A 471 ? HIS A 471 . ? 1_555 ? 23 AC4 16 ASP A 472 ? ASP A 472 . ? 1_555 ? 24 AC4 16 TYR A 727 ? TYR A 727 . ? 1_555 ? 25 AC4 16 GLY A 877 ? GLY A 877 . ? 1_555 ? 26 AC4 16 ZN D . ? ZN A 1805 . ? 1_555 ? 27 AC4 16 HOH G . ? HOH A 2309 . ? 1_555 ? 28 AC4 16 HOH G . ? HOH A 2329 . ? 1_555 ? 29 AC4 16 HOH G . ? HOH A 2333 . ? 1_555 ? 30 AC4 16 HOH G . ? HOH A 2460 . ? 1_555 ? 31 AC4 16 HOH G . ? HOH A 2904 . ? 1_555 ? 32 AC5 8 LYS A 63 ? LYS A 63 . ? 1_555 ? 33 AC5 8 GLN A 64 ? GLN A 64 . ? 1_555 ? 34 AC5 8 TYR A 267 ? TYR A 267 . ? 1_555 ? 35 AC5 8 HIS A 273 ? HIS A 273 . ? 1_555 ? 36 AC5 8 HOH G . ? HOH A 2470 . ? 1_555 ? 37 AC5 8 HOH G . ? HOH A 2525 . ? 1_555 ? 38 AC5 8 HOH G . ? HOH A 2534 . ? 1_555 ? 39 AC5 8 HOH G . ? HOH A 2827 . ? 1_555 ? # _database_PDB_matrix.entry_id 2F1A _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2F1A _atom_sites.fract_transf_matrix[1][1] 0.014513 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009144 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007216 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.160 35.768 -18.733 1.00 30.26 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.410 37.034 -18.442 1.00 28.48 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 41.902 36.842 -18.533 1.00 26.70 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.409 36.282 -19.517 1.00 26.39 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.776 38.151 -19.433 1.00 27.77 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.448 38.873 -19.368 1.00 29.75 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.169 37.327 -17.532 1.00 25.13 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.716 37.264 -17.536 1.00 25.50 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.217 38.206 -18.643 1.00 22.48 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.825 39.256 -18.940 1.00 21.44 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.105 37.800 -16.230 1.00 27.03 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 39.275 36.985 -14.972 1.00 30.20 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 38.180 37.333 -13.941 1.00 31.53 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 37.058 36.819 -14.007 1.00 33.18 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.500 38.226 -13.005 1.00 30.40 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.103 37.833 -19.248 1.00 22.83 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.484 38.651 -20.281 1.00 19.40 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.544 39.621 -19.528 1.00 22.20 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.575 39.214 -18.870 1.00 24.50 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.724 37.705 -21.233 1.00 21.71 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 36.007 38.427 -22.366 1.00 27.05 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.548 39.577 -22.211 1.00 24.97 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 35.850 37.789 -23.431 1.00 27.92 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.821 40.914 -19.632 1.00 16.22 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 36.030 41.878 -18.894 1.00 15.52 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.848 42.444 -19.662 1.00 14.83 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.116 43.292 -19.175 1.00 16.35 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 36.921 43.049 -18.409 1.00 15.29 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.151 42.489 -17.671 1.00 17.50 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.432 43.901 -19.595 1.00 15.81 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.614 41.892 -20.849 1.00 15.65 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.505 42.371 -21.675 1.00 15.70 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.318 41.396 -21.902 1.00 15.48 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.153 41.769 -21.817 1.00 16.27 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 34.023 42.723 -23.075 1.00 15.70 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 32.840 43.104 -23.995 1.00 16.46 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.109 43.864 -22.993 1.00 15.87 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.652 40.143 -22.171 1.00 17.12 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.687 39.131 -22.589 1.00 19.23 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 31.073 38.217 -21.564 1.00 22.28 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 30.157 37.494 -21.889 1.00 27.10 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.363 38.297 -23.679 1.00 18.78 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 32.991 39.160 -24.748 1.00 21.40 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.448 38.371 -25.933 1.00 23.82 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.686 38.169 -26.866 1.00 25.10 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.685 37.906 -25.903 1.00 22.35 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.559 38.249 -20.334 1.00 23.06 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 31.045 37.389 -19.287 1.00 24.80 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.349 38.206 -18.177 1.00 22.28 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 31.026 38.809 -17.340 1.00 25.13 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 32.215 36.584 -18.672 1.00 27.44 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 32.873 35.604 -19.667 1.00 30.15 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 32.132 34.961 -20.427 1.00 32.56 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 34.122 35.472 -19.677 1.00 30.70 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 29.031 38.210 -18.151 1.00 21.22 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.318 38.957 -17.104 1.00 19.55 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.497 38.245 -15.760 1.00 21.11 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 28.071 37.102 -15.609 1.00 20.64 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 26.818 39.055 -17.403 1.00 20.53 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 26.085 39.802 -16.261 1.00 18.68 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.604 39.759 -18.781 1.00 20.20 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 29.109 38.905 -14.762 1.00 19.12 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.282 38.213 -13.478 1.00 16.77 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 27.981 37.863 -12.807 1.00 17.79 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 26.999 38.595 -12.867 1.00 17.37 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 30.060 39.219 -12.630 1.00 18.15 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 30.883 40.011 -13.668 1.00 16.98 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 29.813 40.209 -14.771 1.00 17.90 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 27.995 36.712 -12.131 1.00 18.15 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 26.826 36.297 -11.398 1.00 19.87 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 27.090 36.675 -9.936 1.00 17.61 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 27.990 36.120 -9.279 1.00 18.86 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.629 34.789 -11.593 1.00 24.70 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.547 34.220 -10.719 1.00 28.58 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.500 34.842 -10.486 1.00 33.86 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 25.786 33.009 -10.224 1.00 35.00 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.324 37.643 -9.448 1.00 16.61 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.475 38.106 -8.060 1.00 15.10 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.124 38.100 -7.386 1.00 16.58 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.069 38.211 -8.016 1.00 19.01 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.093 39.565 -7.985 1.00 15.17 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.543 39.555 -8.441 1.00 16.56 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.252 40.536 -8.826 1.00 15.77 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.135 38.014 -6.062 1.00 15.18 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 23.880 38.029 -5.336 1.00 14.78 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.174 39.389 -5.335 1.00 15.59 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 21.937 39.478 -5.345 1.00 17.55 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.106 37.584 -3.877 1.00 17.23 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.651 36.177 -3.784 1.00 21.92 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 24.046 35.264 -4.412 1.00 21.74 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.675 35.953 -3.108 1.00 17.93 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 23.963 40.463 -5.276 1.00 14.95 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.435 41.819 -5.272 1.00 15.20 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.206 42.591 -6.357 1.00 13.56 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.439 42.662 -6.309 1.00 15.12 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.664 42.539 -3.923 1.00 15.27 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 23.081 43.954 -3.992 1.00 15.22 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 22.967 41.754 -2.772 1.00 16.51 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.477 43.124 -7.342 1.00 13.69 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.129 43.927 -8.383 1.00 14.52 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.404 45.255 -8.223 1.00 14.47 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.207 45.344 -8.384 1.00 14.74 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 23.925 43.282 -9.746 1.00 15.82 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 24.993 43.695 -10.749 1.00 13.87 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.057 45.216 -10.906 1.00 14.22 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.061 45.846 -11.250 1.00 16.25 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.226 45.811 -10.617 1.00 13.07 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.140 46.301 -7.840 1.00 13.03 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.462 47.532 -7.492 1.00 12.91 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.552 48.197 -8.532 1.00 12.91 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.550 48.818 -8.150 1.00 13.13 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.464 48.519 -6.912 1.00 13.76 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 25.076 48.067 -5.577 1.00 12.66 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 23.863 47.785 -4.277 1.00 16.01 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.236 49.512 -4.104 1.00 17.27 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 22.910 48.076 -9.806 1.00 13.01 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 22.043 48.674 -10.830 1.00 13.65 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.707 47.885 -10.861 1.00 15.48 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.638 48.477 -10.968 1.00 14.22 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.715 48.636 -12.179 1.00 15.06 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 21.886 49.369 -13.247 1.00 14.26 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 21.905 50.885 -13.025 1.00 15.71 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.469 49.003 -14.566 1.00 16.24 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.799 46.565 -10.729 1.00 15.63 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.594 45.732 -10.720 1.00 16.30 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.774 46.038 -9.477 1.00 17.75 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.555 46.203 -9.532 1.00 18.11 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 19.998 44.250 -10.770 1.00 17.06 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.822 43.284 -11.006 1.00 20.56 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 18.032 42.961 -9.775 1.00 24.27 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.539 43.099 -8.638 1.00 24.47 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 16.868 42.530 -9.930 1.00 29.40 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.448 46.184 -8.337 1.00 14.23 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.757 46.491 -7.106 1.00 16.38 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 18.024 47.807 -7.256 1.00 16.28 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.869 47.956 -6.880 1.00 18.38 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.749 46.556 -5.929 1.00 17.62 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 19.054 46.690 -4.587 1.00 17.71 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 18.127 45.495 -4.372 1.00 26.27 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 20.090 46.714 -3.439 1.00 21.67 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.702 48.813 -7.792 1.00 15.44 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 18.036 50.080 -7.999 1.00 16.24 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.801 50.007 -8.919 1.00 15.91 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.834 50.729 -8.712 1.00 17.04 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.059 51.071 -8.590 1.00 14.73 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.633 52.012 -7.561 1.00 14.31 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.109 51.532 -6.346 1.00 14.76 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.640 53.385 -7.779 1.00 13.75 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.559 52.382 -5.383 1.00 14.14 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.082 54.269 -6.808 1.00 14.71 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.532 53.752 -5.601 1.00 14.24 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 20.887 54.593 -4.591 1.00 15.50 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.848 49.151 -9.927 1.00 16.11 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.718 49.087 -10.837 1.00 18.61 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.471 48.533 -10.130 1.00 19.45 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.339 48.942 -10.486 1.00 20.23 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.116 48.219 -12.007 1.00 18.65 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.262 48.419 -13.217 1.00 24.33 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 14.557 49.436 -13.313 1.00 27.84 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 15.361 47.538 -14.101 1.00 30.03 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.692 47.630 -9.173 1.00 19.50 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.622 46.952 -8.401 1.00 21.23 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.105 47.691 -7.183 1.00 21.46 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 11.928 47.587 -6.856 1.00 24.23 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 14.106 45.586 -7.866 1.00 24.83 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 14.377 44.508 -8.857 1.00 32.74 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 15.323 43.447 -8.230 1.00 37.40 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 15.105 43.264 -6.805 1.00 39.10 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 16.057 42.958 -5.927 1.00 40.27 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 17.318 42.781 -6.317 1.00 39.57 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 15.743 42.875 -4.640 1.00 41.19 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 13.989 48.418 -6.500 1.00 20.56 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.628 49.149 -5.287 1.00 21.25 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.590 50.230 -5.463 1.00 20.53 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.570 50.919 -6.473 1.00 20.57 ? 52 MET A O 1 ATOM 176 C CB . MET A 1 52 ? 14.871 49.806 -4.683 1.00 20.78 ? 52 MET A CB 1 ATOM 177 C CG A MET A 1 52 ? 15.878 48.842 -4.127 0.50 21.39 ? 52 MET A CG 1 ATOM 178 C CG B MET A 1 52 ? 15.613 48.726 -3.748 0.50 22.42 ? 52 MET A CG 1 ATOM 179 S SD A MET A 1 52 ? 17.457 49.713 -3.698 0.50 21.09 ? 52 MET A SD 1 ATOM 180 S SD B MET A 1 52 ? 17.208 49.465 -3.231 0.50 24.89 ? 52 MET A SD 1 ATOM 181 C CE A MET A 1 52 ? 16.921 51.009 -2.537 0.50 18.64 ? 52 MET A CE 1 ATOM 182 C CE B MET A 1 52 ? 16.708 50.960 -2.407 0.50 24.05 ? 52 MET A CE 1 ATOM 183 N N . SER A 1 53 ? 11.746 50.402 -4.446 1.00 19.88 ? 53 SER A N 1 ATOM 184 C CA . SER A 1 53 ? 10.698 51.425 -4.472 1.00 21.65 ? 53 SER A CA 1 ATOM 185 C C . SER A 1 53 ? 11.138 52.773 -3.891 1.00 20.10 ? 53 SER A C 1 ATOM 186 O O . SER A 1 53 ? 10.530 53.809 -4.160 1.00 21.28 ? 53 SER A O 1 ATOM 187 C CB A SER A 1 53 ? 9.470 50.924 -3.696 0.50 21.98 ? 53 SER A CB 1 ATOM 188 C CB B SER A 1 53 ? 9.343 51.059 -3.964 0.50 21.56 ? 53 SER A CB 1 ATOM 189 O OG A SER A 1 53 ? 8.929 49.793 -4.345 0.50 26.32 ? 53 SER A OG 1 ATOM 190 O OG B SER A 1 53 ? 9.443 50.803 -2.578 0.50 22.79 ? 53 SER A OG 1 ATOM 191 N N . PHE A 1 54 ? 12.171 52.752 -3.064 1.00 19.40 ? 54 PHE A N 1 ATOM 192 C CA . PHE A 1 54 ? 12.684 53.964 -2.436 1.00 17.54 ? 54 PHE A CA 1 ATOM 193 C C . PHE A 1 54 ? 11.653 54.773 -1.626 1.00 19.25 ? 54 PHE A C 1 ATOM 194 O O . PHE A 1 54 ? 11.752 56.010 -1.484 1.00 19.76 ? 54 PHE A O 1 ATOM 195 C CB . PHE A 1 54 ? 13.343 54.891 -3.480 1.00 18.96 ? 54 PHE A CB 1 ATOM 196 C CG . PHE A 1 54 ? 14.615 54.340 -4.084 1.00 15.71 ? 54 PHE A CG 1 ATOM 197 C CD1 . PHE A 1 54 ? 14.561 53.509 -5.182 1.00 17.99 ? 54 PHE A CD1 1 ATOM 198 C CD2 . PHE A 1 54 ? 15.860 54.695 -3.567 1.00 17.52 ? 54 PHE A CD2 1 ATOM 199 C CE1 . PHE A 1 54 ? 15.734 53.020 -5.781 1.00 16.87 ? 54 PHE A CE1 1 ATOM 200 C CE2 . PHE A 1 54 ? 17.032 54.235 -4.146 1.00 17.81 ? 54 PHE A CE2 1 ATOM 201 C CZ . PHE A 1 54 ? 16.988 53.390 -5.257 1.00 18.01 ? 54 PHE A CZ 1 ATOM 202 N N . LYS A 1 55 ? 10.665 54.081 -1.053 1.00 20.47 ? 55 LYS A N 1 ATOM 203 C CA . LYS A 1 55 ? 9.681 54.817 -0.247 1.00 21.47 ? 55 LYS A CA 1 ATOM 204 C C . LYS A 1 55 ? 10.287 55.263 1.047 1.00 21.81 ? 55 LYS A C 1 ATOM 205 O O . LYS A 1 55 ? 10.999 54.515 1.694 1.00 22.44 ? 55 LYS A O 1 ATOM 206 C CB . LYS A 1 55 ? 8.448 53.957 0.084 1.00 21.61 ? 55 LYS A CB 1 ATOM 207 C CG . LYS A 1 55 ? 7.692 53.492 -1.131 1.00 22.92 ? 55 LYS A CG 1 ATOM 208 C CD . LYS A 1 55 ? 7.454 54.621 -2.142 1.00 23.36 ? 55 LYS A CD 1 ATOM 209 C CE . LYS A 1 55 ? 6.683 54.100 -3.362 1.00 25.88 ? 55 LYS A CE 1 ATOM 210 N NZ . LYS A 1 55 ? 6.270 55.230 -4.285 1.00 27.87 ? 55 LYS A NZ 1 ATOM 211 N N . ASP A 1 56 ? 9.993 56.489 1.436 1.00 21.22 ? 56 ASP A N 1 ATOM 212 C CA . ASP A 1 56 ? 10.527 57.052 2.647 1.00 21.42 ? 56 ASP A CA 1 ATOM 213 C C . ASP A 1 56 ? 9.475 57.069 3.760 1.00 23.00 ? 56 ASP A C 1 ATOM 214 O O . ASP A 1 56 ? 8.889 58.104 4.089 1.00 25.98 ? 56 ASP A O 1 ATOM 215 C CB . ASP A 1 56 ? 11.042 58.459 2.305 1.00 20.21 ? 56 ASP A CB 1 ATOM 216 C CG . ASP A 1 56 ? 11.669 59.170 3.486 1.00 20.28 ? 56 ASP A CG 1 ATOM 217 O OD1 . ASP A 1 56 ? 12.211 58.525 4.404 1.00 20.89 ? 56 ASP A OD1 1 ATOM 218 O OD2 . ASP A 1 56 ? 11.626 60.418 3.464 1.00 24.19 ? 56 ASP A OD2 1 ATOM 219 N N . ILE A 1 57 ? 9.272 55.915 4.368 1.00 22.60 ? 57 ILE A N 1 ATOM 220 C CA . ILE A 1 57 ? 8.267 55.852 5.402 1.00 24.17 ? 57 ILE A CA 1 ATOM 221 C C . ILE A 1 57 ? 8.862 55.850 6.779 1.00 23.57 ? 57 ILE A C 1 ATOM 222 O O . ILE A 1 57 ? 9.999 55.431 6.996 1.00 23.69 ? 57 ILE A O 1 ATOM 223 C CB . ILE A 1 57 ? 7.345 54.617 5.226 1.00 26.87 ? 57 ILE A CB 1 ATOM 224 C CG1 . ILE A 1 57 ? 8.132 53.342 5.415 1.00 28.37 ? 57 ILE A CG1 1 ATOM 225 C CG2 . ILE A 1 57 ? 6.704 54.593 3.803 1.00 26.53 ? 57 ILE A CG2 1 ATOM 226 C CD1 . ILE A 1 57 ? 7.240 52.185 5.803 1.00 30.30 ? 57 ILE A CD1 1 ATOM 227 N N . ASP A 1 58 ? 8.064 56.315 7.732 1.00 23.14 ? 58 ASP A N 1 ATOM 228 C CA . ASP A 1 58 ? 8.477 56.386 9.122 1.00 24.81 ? 58 ASP A CA 1 ATOM 229 C C . ASP A 1 58 ? 8.526 54.971 9.683 1.00 24.46 ? 58 ASP A C 1 ATOM 230 O O . ASP A 1 58 ? 7.490 54.341 9.861 1.00 25.20 ? 58 ASP A O 1 ATOM 231 C CB . ASP A 1 58 ? 7.462 57.229 9.876 1.00 26.83 ? 58 ASP A CB 1 ATOM 232 C CG . ASP A 1 58 ? 7.864 57.493 11.310 1.00 29.00 ? 58 ASP A CG 1 ATOM 233 O OD1 . ASP A 1 58 ? 8.719 56.772 11.850 1.00 26.46 ? 58 ASP A OD1 1 ATOM 234 O OD2 . ASP A 1 58 ? 7.312 58.445 11.917 1.00 34.45 ? 58 ASP A OD2 1 ATOM 235 N N . GLY A 1 59 ? 9.721 54.450 9.937 1.00 22.01 ? 59 GLY A N 1 ATOM 236 C CA . GLY A 1 59 ? 9.832 53.096 10.451 1.00 22.10 ? 59 GLY A CA 1 ATOM 237 C C . GLY A 1 59 ? 9.763 52.985 11.967 1.00 20.49 ? 59 GLY A C 1 ATOM 238 O O . GLY A 1 59 ? 9.961 51.903 12.484 1.00 22.25 ? 59 GLY A O 1 ATOM 239 N N . GLY A 1 60 ? 9.522 54.098 12.664 1.00 21.87 ? 60 GLY A N 1 ATOM 240 C CA . GLY A 1 60 ? 9.478 54.068 14.117 1.00 22.11 ? 60 GLY A CA 1 ATOM 241 C C . GLY A 1 60 ? 10.735 54.677 14.726 1.00 20.66 ? 60 GLY A C 1 ATOM 242 O O . GLY A 1 60 ? 11.287 55.644 14.183 1.00 21.03 ? 60 GLY A O 1 ATOM 243 N N . VAL A 1 61 ? 11.214 54.139 15.852 1.00 20.06 ? 61 VAL A N 1 ATOM 244 C CA . VAL A 1 61 ? 12.395 54.737 16.465 1.00 18.45 ? 61 VAL A CA 1 ATOM 245 C C . VAL A 1 61 ? 13.575 54.651 15.445 1.00 17.48 ? 61 VAL A C 1 ATOM 246 O O . VAL A 1 61 ? 14.440 55.542 15.434 1.00 17.83 ? 61 VAL A O 1 ATOM 247 C CB . VAL A 1 61 ? 12.774 54.099 17.834 1.00 18.51 ? 61 VAL A CB 1 ATOM 248 C CG1 . VAL A 1 61 ? 11.690 54.432 18.895 1.00 20.55 ? 61 VAL A CG1 1 ATOM 249 C CG2 . VAL A 1 61 ? 12.949 52.589 17.699 1.00 20.18 ? 61 VAL A CG2 1 ATOM 250 N N . TRP A 1 62 ? 13.626 53.587 14.654 1.00 18.71 ? 62 TRP A N 1 ATOM 251 C CA . TRP A 1 62 ? 14.640 53.486 13.589 1.00 16.04 ? 62 TRP A CA 1 ATOM 252 C C . TRP A 1 62 ? 13.841 54.121 12.473 1.00 16.86 ? 62 TRP A C 1 ATOM 253 O O . TRP A 1 62 ? 13.086 53.444 11.762 1.00 17.78 ? 62 TRP A O 1 ATOM 254 C CB . TRP A 1 62 ? 14.963 52.042 13.244 1.00 15.53 ? 62 TRP A CB 1 ATOM 255 C CG . TRP A 1 62 ? 15.953 51.930 12.119 1.00 14.56 ? 62 TRP A CG 1 ATOM 256 C CD1 . TRP A 1 62 ? 16.644 52.969 11.511 1.00 16.17 ? 62 TRP A CD1 1 ATOM 257 C CD2 . TRP A 1 62 ? 16.307 50.749 11.440 1.00 15.76 ? 62 TRP A CD2 1 ATOM 258 N NE1 . TRP A 1 62 ? 17.389 52.469 10.484 1.00 15.73 ? 62 TRP A NE1 1 ATOM 259 C CE2 . TRP A 1 62 ? 17.214 51.108 10.413 1.00 15.95 ? 62 TRP A CE2 1 ATOM 260 C CE3 . TRP A 1 62 ? 15.945 49.399 11.587 1.00 14.32 ? 62 TRP A CE3 1 ATOM 261 C CZ2 . TRP A 1 62 ? 17.771 50.159 9.523 1.00 16.42 ? 62 TRP A CZ2 1 ATOM 262 C CZ3 . TRP A 1 62 ? 16.490 48.461 10.721 1.00 15.01 ? 62 TRP A CZ3 1 ATOM 263 C CH2 . TRP A 1 62 ? 17.406 48.844 9.686 1.00 15.71 ? 62 TRP A CH2 1 ATOM 264 N N . LYS A 1 63 ? 14.031 55.433 12.286 1.00 16.61 ? 63 LYS A N 1 ATOM 265 C CA . LYS A 1 63 ? 13.185 56.158 11.332 1.00 17.03 ? 63 LYS A CA 1 ATOM 266 C C . LYS A 1 63 ? 13.151 55.665 9.909 1.00 18.76 ? 63 LYS A C 1 ATOM 267 O O . LYS A 1 63 ? 12.111 55.760 9.233 1.00 21.34 ? 63 LYS A O 1 ATOM 268 C CB . LYS A 1 63 ? 13.564 57.643 11.354 1.00 17.54 ? 63 LYS A CB 1 ATOM 269 C CG . LYS A 1 63 ? 13.154 58.375 12.652 1.00 24.79 ? 63 LYS A CG 1 ATOM 270 C CD . LYS A 1 63 ? 11.639 58.713 12.651 1.00 28.59 ? 63 LYS A CD 1 ATOM 271 C CE . LYS A 1 63 ? 11.195 59.528 13.863 1.00 32.96 ? 63 LYS A CE 1 ATOM 272 N NZ . LYS A 1 63 ? 11.227 58.797 15.192 1.00 36.65 ? 63 LYS A NZ 1 ATOM 273 N N . GLN A 1 64 ? 14.269 55.132 9.437 1.00 17.24 ? 64 GLN A N 1 ATOM 274 C CA . GLN A 1 64 ? 14.355 54.669 8.064 1.00 17.33 ? 64 GLN A CA 1 ATOM 275 C C . GLN A 1 64 ? 14.421 53.173 7.916 1.00 15.96 ? 64 GLN A C 1 ATOM 276 O O . GLN A 1 64 ? 14.723 52.642 6.844 1.00 16.66 ? 64 GLN A O 1 ATOM 277 C CB . GLN A 1 64 ? 15.567 55.344 7.371 1.00 16.07 ? 64 GLN A CB 1 ATOM 278 C CG . GLN A 1 64 ? 15.442 56.861 7.396 1.00 17.72 ? 64 GLN A CG 1 ATOM 279 C CD . GLN A 1 64 ? 16.810 57.548 7.270 1.00 15.93 ? 64 GLN A CD 1 ATOM 280 O OE1 . GLN A 1 64 ? 17.741 57.233 8.007 1.00 17.44 ? 64 GLN A OE1 1 ATOM 281 N NE2 . GLN A 1 64 ? 16.903 58.510 6.358 1.00 15.17 ? 64 GLN A NE2 1 ATOM 282 N N . GLY A 1 65 ? 14.055 52.493 9.010 1.00 16.23 ? 65 GLY A N 1 ATOM 283 C CA . GLY A 1 65 ? 14.014 51.029 9.002 1.00 16.70 ? 65 GLY A CA 1 ATOM 284 C C . GLY A 1 65 ? 12.656 50.467 9.421 1.00 18.52 ? 65 GLY A C 1 ATOM 285 O O . GLY A 1 65 ? 11.615 50.823 8.841 1.00 19.17 ? 65 GLY A O 1 ATOM 286 N N . TRP A 1 66 ? 12.683 49.604 10.424 1.00 18.12 ? 66 TRP A N 1 ATOM 287 C CA . TRP A 1 66 ? 11.431 48.996 10.943 1.00 18.32 ? 66 TRP A CA 1 ATOM 288 C C . TRP A 1 66 ? 11.696 48.608 12.371 1.00 20.07 ? 66 TRP A C 1 ATOM 289 O O . TRP A 1 66 ? 12.823 48.720 12.851 1.00 19.21 ? 66 TRP A O 1 ATOM 290 C CB . TRP A 1 66 ? 11.041 47.773 10.089 1.00 19.19 ? 66 TRP A CB 1 ATOM 291 C CG . TRP A 1 66 ? 12.001 46.612 10.260 1.00 18.33 ? 66 TRP A CG 1 ATOM 292 C CD1 . TRP A 1 66 ? 11.912 45.587 11.177 1.00 18.52 ? 66 TRP A CD1 1 ATOM 293 C CD2 . TRP A 1 66 ? 13.210 46.371 9.525 1.00 17.50 ? 66 TRP A CD2 1 ATOM 294 N NE1 . TRP A 1 66 ? 12.974 44.730 11.061 1.00 19.43 ? 66 TRP A NE1 1 ATOM 295 C CE2 . TRP A 1 66 ? 13.795 45.178 10.054 1.00 17.46 ? 66 TRP A CE2 1 ATOM 296 C CE3 . TRP A 1 66 ? 13.862 47.040 8.471 1.00 17.86 ? 66 TRP A CE3 1 ATOM 297 C CZ2 . TRP A 1 66 ? 14.989 44.644 9.574 1.00 20.42 ? 66 TRP A CZ2 1 ATOM 298 C CZ3 . TRP A 1 66 ? 15.046 46.504 7.997 1.00 19.29 ? 66 TRP A CZ3 1 ATOM 299 C CH2 . TRP A 1 66 ? 15.605 45.320 8.547 1.00 17.23 ? 66 TRP A CH2 1 ATOM 300 N N . ASN A 1 67 ? 10.657 48.184 13.105 1.00 20.11 ? 67 ASN A N 1 ATOM 301 C CA . ASN A 1 67 ? 10.883 47.765 14.497 1.00 20.43 ? 67 ASN A CA 1 ATOM 302 C C . ASN A 1 67 ? 11.481 46.361 14.514 1.00 20.09 ? 67 ASN A C 1 ATOM 303 O O . ASN A 1 67 ? 10.789 45.352 14.235 1.00 19.04 ? 67 ASN A O 1 ATOM 304 C CB . ASN A 1 67 ? 9.576 47.728 15.297 1.00 22.53 ? 67 ASN A CB 1 ATOM 305 C CG . ASN A 1 67 ? 8.958 49.071 15.472 1.00 24.79 ? 67 ASN A CG 1 ATOM 306 O OD1 . ASN A 1 67 ? 9.647 50.090 15.605 1.00 26.71 ? 67 ASN A OD1 1 ATOM 307 N ND2 . ASN A 1 67 ? 7.628 49.094 15.520 1.00 29.89 ? 67 ASN A ND2 1 ATOM 308 N N . ILE A 1 68 ? 12.759 46.289 14.845 1.00 18.88 ? 68 ILE A N 1 ATOM 309 C CA . ILE A 1 68 ? 13.459 45.031 14.841 1.00 19.89 ? 68 ILE A CA 1 ATOM 310 C C . ILE A 1 68 ? 13.016 44.126 15.987 1.00 21.36 ? 68 ILE A C 1 ATOM 311 O O . ILE A 1 68 ? 12.924 44.563 17.127 1.00 22.37 ? 68 ILE A O 1 ATOM 312 C CB . ILE A 1 68 ? 15.011 45.237 14.931 1.00 20.54 ? 68 ILE A CB 1 ATOM 313 C CG1 . ILE A 1 68 ? 15.539 46.037 13.721 1.00 21.02 ? 68 ILE A CG1 1 ATOM 314 C CG2 . ILE A 1 68 ? 15.700 43.877 14.985 1.00 21.28 ? 68 ILE A CG2 1 ATOM 315 C CD1 . ILE A 1 68 ? 17.006 46.530 13.935 1.00 19.62 ? 68 ILE A CD1 1 ATOM 316 N N . LYS A 1 69 ? 12.768 42.865 15.665 1.00 23.90 ? 69 LYS A N 1 ATOM 317 C CA . LYS A 1 69 ? 12.383 41.892 16.686 1.00 24.59 ? 69 LYS A CA 1 ATOM 318 C C . LYS A 1 69 ? 13.414 40.764 16.641 1.00 23.92 ? 69 LYS A C 1 ATOM 319 O O . LYS A 1 69 ? 13.972 40.454 15.589 1.00 23.62 ? 69 LYS A O 1 ATOM 320 C CB . LYS A 1 69 ? 10.977 41.336 16.401 1.00 29.34 ? 69 LYS A CB 1 ATOM 321 C CG . LYS A 1 69 ? 9.842 42.318 16.707 1.00 33.66 ? 69 LYS A CG 1 ATOM 322 C CD . LYS A 1 69 ? 8.524 41.895 16.038 1.00 41.21 ? 69 LYS A CD 1 ATOM 323 C CE . LYS A 1 69 ? 8.132 40.433 16.372 1.00 45.30 ? 69 LYS A CE 1 ATOM 324 N NZ . LYS A 1 69 ? 6.898 39.971 15.628 1.00 45.81 ? 69 LYS A NZ 1 ATOM 325 N N . TYR A 1 70 ? 13.708 40.180 17.793 1.00 23.74 ? 70 TYR A N 1 ATOM 326 C CA . TYR A 1 70 ? 14.651 39.058 17.830 1.00 22.31 ? 70 TYR A CA 1 ATOM 327 C C . TYR A 1 70 ? 14.100 37.998 18.798 1.00 25.22 ? 70 TYR A C 1 ATOM 328 O O . TYR A 1 70 ? 13.269 38.308 19.656 1.00 25.43 ? 70 TYR A O 1 ATOM 329 C CB . TYR A 1 70 ? 16.050 39.508 18.302 1.00 22.43 ? 70 TYR A CB 1 ATOM 330 C CG . TYR A 1 70 ? 16.100 40.129 19.670 1.00 20.69 ? 70 TYR A CG 1 ATOM 331 C CD1 . TYR A 1 70 ? 15.851 41.472 19.843 1.00 22.02 ? 70 TYR A CD1 1 ATOM 332 C CD2 . TYR A 1 70 ? 16.427 39.367 20.801 1.00 22.30 ? 70 TYR A CD2 1 ATOM 333 C CE1 . TYR A 1 70 ? 15.922 42.067 21.079 1.00 24.21 ? 70 TYR A CE1 1 ATOM 334 C CE2 . TYR A 1 70 ? 16.504 39.968 22.067 1.00 24.09 ? 70 TYR A CE2 1 ATOM 335 C CZ . TYR A 1 70 ? 16.242 41.318 22.188 1.00 22.55 ? 70 TYR A CZ 1 ATOM 336 O OH . TYR A 1 70 ? 16.251 41.927 23.426 1.00 26.03 ? 70 TYR A OH 1 ATOM 337 N N . ASP A 1 71 ? 14.558 36.765 18.610 1.00 26.48 ? 71 ASP A N 1 ATOM 338 C CA . ASP A 1 71 ? 14.181 35.631 19.444 1.00 28.14 ? 71 ASP A CA 1 ATOM 339 C C . ASP A 1 71 ? 15.168 35.568 20.596 1.00 27.84 ? 71 ASP A C 1 ATOM 340 O O . ASP A 1 71 ? 16.329 35.221 20.413 1.00 28.49 ? 71 ASP A O 1 ATOM 341 C CB . ASP A 1 71 ? 14.251 34.347 18.632 1.00 30.16 ? 71 ASP A CB 1 ATOM 342 C CG . ASP A 1 71 ? 13.837 33.115 19.455 1.00 32.90 ? 71 ASP A CG 1 ATOM 343 O OD1 . ASP A 1 71 ? 13.675 33.233 20.690 1.00 33.51 ? 71 ASP A OD1 1 ATOM 344 O OD2 . ASP A 1 71 ? 13.680 32.040 18.852 1.00 36.53 ? 71 ASP A OD2 1 ATOM 345 N N . PRO A 1 72 ? 14.715 35.916 21.807 1.00 30.02 ? 72 PRO A N 1 ATOM 346 C CA . PRO A 1 72 ? 15.604 35.889 22.966 1.00 30.93 ? 72 PRO A CA 1 ATOM 347 C C . PRO A 1 72 ? 16.369 34.573 23.137 1.00 29.58 ? 72 PRO A C 1 ATOM 348 O O . PRO A 1 72 ? 17.464 34.560 23.682 1.00 31.56 ? 72 PRO A O 1 ATOM 349 C CB . PRO A 1 72 ? 14.660 36.210 24.130 1.00 30.34 ? 72 PRO A CB 1 ATOM 350 C CG . PRO A 1 72 ? 13.315 35.694 23.634 1.00 33.40 ? 72 PRO A CG 1 ATOM 351 C CD . PRO A 1 72 ? 13.318 36.159 22.204 1.00 29.88 ? 72 PRO A CD 1 ATOM 352 N N . LEU A 1 73 ? 15.812 33.476 22.639 1.00 30.28 ? 73 LEU A N 1 ATOM 353 C CA . LEU A 1 73 ? 16.458 32.168 22.748 1.00 30.73 ? 73 LEU A CA 1 ATOM 354 C C . LEU A 1 73 ? 17.534 31.917 21.694 1.00 29.03 ? 73 LEU A C 1 ATOM 355 O O . LEU A 1 73 ? 18.150 30.856 21.671 1.00 29.81 ? 73 LEU A O 1 ATOM 356 C CB . LEU A 1 73 ? 15.402 31.061 22.650 1.00 31.40 ? 73 LEU A CB 1 ATOM 357 C CG . LEU A 1 73 ? 14.291 31.179 23.690 1.00 33.86 ? 73 LEU A CG 1 ATOM 358 C CD1 . LEU A 1 73 ? 13.214 30.094 23.468 1.00 35.37 ? 73 LEU A CD1 1 ATOM 359 C CD2 . LEU A 1 73 ? 14.928 31.076 25.066 1.00 32.73 ? 73 LEU A CD2 1 ATOM 360 N N . LYS A 1 74 ? 17.753 32.881 20.799 1.00 28.38 ? 74 LYS A N 1 ATOM 361 C CA . LYS A 1 74 ? 18.777 32.733 19.776 1.00 27.82 ? 74 LYS A CA 1 ATOM 362 C C . LYS A 1 74 ? 20.162 32.574 20.409 1.00 27.53 ? 74 LYS A C 1 ATOM 363 O O . LYS A 1 74 ? 21.028 31.839 19.912 1.00 28.09 ? 74 LYS A O 1 ATOM 364 C CB . LYS A 1 74 ? 18.771 33.976 18.886 1.00 28.79 ? 74 LYS A CB 1 ATOM 365 C CG . LYS A 1 74 ? 19.754 33.924 17.732 1.00 31.74 ? 74 LYS A CG 1 ATOM 366 C CD . LYS A 1 74 ? 19.536 35.148 16.856 1.00 32.93 ? 74 LYS A CD 1 ATOM 367 C CE . LYS A 1 74 ? 20.343 35.087 15.575 1.00 35.04 ? 74 LYS A CE 1 ATOM 368 N NZ . LYS A 1 74 ? 19.836 36.150 14.657 1.00 38.04 ? 74 LYS A NZ 1 ATOM 369 N N . TYR A 1 75 ? 20.406 33.313 21.485 1.00 28.91 ? 75 TYR A N 1 ATOM 370 C CA . TYR A 1 75 ? 21.695 33.234 22.155 1.00 28.48 ? 75 TYR A CA 1 ATOM 371 C C . TYR A 1 75 ? 21.492 32.504 23.483 1.00 28.69 ? 75 TYR A C 1 ATOM 372 O O A TYR A 1 75 ? 20.461 32.678 24.132 0.50 30.37 ? 75 TYR A O 1 ATOM 373 O O B TYR A 1 75 ? 20.304 32.292 23.984 0.50 29.74 ? 75 TYR A O 1 ATOM 374 C CB A TYR A 1 75 ? 22.290 34.644 22.339 0.50 29.19 ? 75 TYR A CB 1 ATOM 375 C CB B TYR A 1 75 ? 22.102 34.570 22.630 0.50 27.89 ? 75 TYR A CB 1 ATOM 376 C CG A TYR A 1 75 ? 22.655 35.297 21.012 0.50 27.30 ? 75 TYR A CG 1 ATOM 377 C CG B TYR A 1 75 ? 22.084 35.526 21.486 0.50 25.52 ? 75 TYR A CG 1 ATOM 378 C CD1 A TYR A 1 75 ? 21.838 36.275 20.434 0.50 29.18 ? 75 TYR A CD1 1 ATOM 379 C CD1 B TYR A 1 75 ? 21.031 36.416 21.324 0.50 26.30 ? 75 TYR A CD1 1 ATOM 380 C CD2 A TYR A 1 75 ? 23.767 34.864 20.289 0.50 27.91 ? 75 TYR A CD2 1 ATOM 381 C CD2 B TYR A 1 75 ? 23.081 35.495 20.521 0.50 24.99 ? 75 TYR A CD2 1 ATOM 382 C CE1 A TYR A 1 75 ? 22.119 36.799 19.162 0.50 28.32 ? 75 TYR A CE1 1 ATOM 383 C CE1 B TYR A 1 75 ? 20.967 37.255 20.225 0.50 24.42 ? 75 TYR A CE1 1 ATOM 384 C CE2 A TYR A 1 75 ? 24.054 35.371 19.017 0.50 28.43 ? 75 TYR A CE2 1 ATOM 385 C CE2 B TYR A 1 75 ? 23.028 36.330 19.413 0.50 25.53 ? 75 TYR A CE2 1 ATOM 386 C CZ A TYR A 1 75 ? 23.230 36.332 18.456 0.50 27.58 ? 75 TYR A CZ 1 ATOM 387 C CZ B TYR A 1 75 ? 21.967 37.204 19.277 0.50 24.16 ? 75 TYR A CZ 1 ATOM 388 O OH A TYR A 1 75 ? 23.508 36.781 17.171 0.50 28.24 ? 75 TYR A OH 1 ATOM 389 O OH B TYR A 1 75 ? 21.908 38.022 18.189 0.50 23.28 ? 75 TYR A OH 1 ATOM 390 N N . ASN A 1 76 ? 22.476 31.685 23.852 1.00 27.67 ? 76 ASN A N 1 ATOM 391 C CA . ASN A 1 76 ? 22.440 30.860 25.052 1.00 28.96 ? 76 ASN A CA 1 ATOM 392 C C . ASN A 1 76 ? 23.867 30.557 25.515 1.00 29.17 ? 76 ASN A C 1 ATOM 393 O O . ASN A 1 76 ? 24.834 31.097 24.980 1.00 28.18 ? 76 ASN A O 1 ATOM 394 C CB . ASN A 1 76 ? 21.674 29.556 24.769 1.00 30.43 ? 76 ASN A CB 1 ATOM 395 C CG . ASN A 1 76 ? 22.211 28.810 23.572 1.00 29.61 ? 76 ASN A CG 1 ATOM 396 O OD1 . ASN A 1 76 ? 23.377 28.446 23.534 1.00 31.29 ? 76 ASN A OD1 1 ATOM 397 N ND2 . ASN A 1 76 ? 21.343 28.568 22.577 1.00 35.66 ? 76 ASN A ND2 1 ATOM 398 N N . ALA A 1 77 ? 24.019 29.675 26.497 1.00 28.89 ? 77 ALA A N 1 ATOM 399 C CA . ALA A 1 77 ? 25.354 29.387 27.007 1.00 32.34 ? 77 ALA A CA 1 ATOM 400 C C . ALA A 1 77 ? 26.347 28.902 25.951 1.00 33.22 ? 77 ALA A C 1 ATOM 401 O O . ALA A 1 77 ? 27.539 29.169 26.053 1.00 33.14 ? 77 ALA A O 1 ATOM 402 C CB . ALA A 1 77 ? 25.264 28.366 28.142 1.00 34.56 ? 77 ALA A CB 1 ATOM 403 N N . HIS A 1 78 ? 25.844 28.220 24.925 1.00 35.25 ? 78 HIS A N 1 ATOM 404 C CA . HIS A 1 78 ? 26.704 27.675 23.877 1.00 37.57 ? 78 HIS A CA 1 ATOM 405 C C . HIS A 1 78 ? 26.789 28.544 22.640 1.00 36.78 ? 78 HIS A C 1 ATOM 406 O O . HIS A 1 78 ? 27.502 28.216 21.679 1.00 38.16 ? 78 HIS A O 1 ATOM 407 C CB . HIS A 1 78 ? 26.206 26.279 23.484 1.00 40.74 ? 78 HIS A CB 1 ATOM 408 C CG . HIS A 1 78 ? 26.087 25.345 24.647 1.00 45.11 ? 78 HIS A CG 1 ATOM 409 N ND1 . HIS A 1 78 ? 27.187 24.864 25.330 1.00 47.54 ? 78 HIS A ND1 1 ATOM 410 C CD2 . HIS A 1 78 ? 24.999 24.849 25.285 1.00 45.85 ? 78 HIS A CD2 1 ATOM 411 C CE1 . HIS A 1 78 ? 26.781 24.111 26.339 1.00 47.63 ? 78 HIS A CE1 1 ATOM 412 N NE2 . HIS A 1 78 ? 25.459 24.087 26.335 1.00 48.95 ? 78 HIS A NE2 1 ATOM 413 N N . HIS A 1 79 ? 26.046 29.640 22.655 1.00 32.96 ? 79 HIS A N 1 ATOM 414 C CA . HIS A 1 79 ? 26.048 30.537 21.514 1.00 30.04 ? 79 HIS A CA 1 ATOM 415 C C . HIS A 1 79 ? 25.813 31.939 22.032 1.00 24.05 ? 79 HIS A C 1 ATOM 416 O O . HIS A 1 79 ? 24.686 32.397 22.085 1.00 24.09 ? 79 HIS A O 1 ATOM 417 C CB . HIS A 1 79 ? 24.935 30.157 20.548 1.00 31.89 ? 79 HIS A CB 1 ATOM 418 C CG . HIS A 1 79 ? 25.067 30.814 19.208 1.00 34.86 ? 79 HIS A CG 1 ATOM 419 N ND1 . HIS A 1 79 ? 24.247 31.844 18.796 1.00 35.95 ? 79 HIS A ND1 1 ATOM 420 C CD2 . HIS A 1 79 ? 25.959 30.615 18.206 1.00 33.47 ? 79 HIS A CD2 1 ATOM 421 C CE1 . HIS A 1 79 ? 24.630 32.252 17.598 1.00 35.42 ? 79 HIS A CE1 1 ATOM 422 N NE2 . HIS A 1 79 ? 25.666 31.524 17.219 1.00 33.89 ? 79 HIS A NE2 1 ATOM 423 N N . LYS A 1 80 ? 26.901 32.589 22.419 1.00 23.08 ? 80 LYS A N 1 ATOM 424 C CA . LYS A 1 80 ? 26.812 33.923 22.965 1.00 20.91 ? 80 LYS A CA 1 ATOM 425 C C . LYS A 1 80 ? 27.047 34.965 21.885 1.00 20.64 ? 80 LYS A C 1 ATOM 426 O O . LYS A 1 80 ? 27.663 34.675 20.844 1.00 21.96 ? 80 LYS A O 1 ATOM 427 C CB . LYS A 1 80 ? 27.870 34.098 24.027 1.00 22.33 ? 80 LYS A CB 1 ATOM 428 C CG . LYS A 1 80 ? 27.743 33.040 25.106 1.00 23.44 ? 80 LYS A CG 1 ATOM 429 C CD . LYS A 1 80 ? 28.886 33.090 26.101 1.00 29.06 ? 80 LYS A CD 1 ATOM 430 C CE . LYS A 1 80 ? 29.016 34.403 26.842 1.00 29.60 ? 80 LYS A CE 1 ATOM 431 N NZ . LYS A 1 80 ? 29.891 34.203 28.078 1.00 33.06 ? 80 LYS A NZ 1 ATOM 432 N N . LEU A 1 81 ? 26.557 36.165 22.151 1.00 17.85 ? 81 LEU A N 1 ATOM 433 C CA . LEU A 1 81 ? 26.749 37.292 21.242 1.00 16.75 ? 81 LEU A CA 1 ATOM 434 C C . LEU A 1 81 ? 28.039 37.952 21.712 1.00 18.07 ? 81 LEU A C 1 ATOM 435 O O . LEU A 1 81 ? 28.146 38.355 22.889 1.00 17.34 ? 81 LEU A O 1 ATOM 436 C CB . LEU A 1 81 ? 25.570 38.258 21.363 1.00 18.23 ? 81 LEU A CB 1 ATOM 437 C CG . LEU A 1 81 ? 25.669 39.544 20.494 1.00 17.18 ? 81 LEU A CG 1 ATOM 438 C CD1 . LEU A 1 81 ? 25.643 39.188 19.002 1.00 17.74 ? 81 LEU A CD1 1 ATOM 439 C CD2 . LEU A 1 81 ? 24.499 40.466 20.832 1.00 20.08 ? 81 LEU A CD2 1 ATOM 440 N N . LYS A 1 82 ? 29.029 38.064 20.813 1.00 15.71 ? 82 LYS A N 1 ATOM 441 C CA . LYS A 1 82 ? 30.305 38.666 21.160 1.00 14.63 ? 82 LYS A CA 1 ATOM 442 C C . LYS A 1 82 ? 30.247 40.081 20.637 1.00 15.85 ? 82 LYS A C 1 ATOM 443 O O . LYS A 1 82 ? 30.039 40.284 19.434 1.00 18.29 ? 82 LYS A O 1 ATOM 444 C CB . LYS A 1 82 ? 31.471 37.900 20.514 1.00 18.82 ? 82 LYS A CB 1 ATOM 445 C CG . LYS A 1 82 ? 31.692 36.524 21.137 1.00 29.02 ? 82 LYS A CG 1 ATOM 446 C CD . LYS A 1 82 ? 32.287 36.716 22.571 1.00 38.21 ? 82 LYS A CD 1 ATOM 447 C CE . LYS A 1 82 ? 33.042 35.466 23.156 1.00 41.58 ? 82 LYS A CE 1 ATOM 448 N NZ . LYS A 1 82 ? 32.168 34.410 23.766 1.00 43.04 ? 82 LYS A NZ 1 ATOM 449 N N . VAL A 1 83 ? 30.389 41.047 21.530 1.00 13.74 ? 83 VAL A N 1 ATOM 450 C CA . VAL A 1 83 ? 30.267 42.439 21.150 1.00 14.03 ? 83 VAL A CA 1 ATOM 451 C C . VAL A 1 83 ? 31.604 43.171 21.302 1.00 14.57 ? 83 VAL A C 1 ATOM 452 O O . VAL A 1 83 ? 32.229 43.153 22.369 1.00 15.89 ? 83 VAL A O 1 ATOM 453 C CB . VAL A 1 83 ? 29.196 43.106 22.078 1.00 13.78 ? 83 VAL A CB 1 ATOM 454 C CG1 . VAL A 1 83 ? 28.995 44.607 21.754 1.00 14.65 ? 83 VAL A CG1 1 ATOM 455 C CG2 . VAL A 1 83 ? 27.823 42.381 21.939 1.00 15.68 ? 83 VAL A CG2 1 ATOM 456 N N . PHE A 1 84 ? 32.035 43.859 20.247 1.00 14.71 ? 84 PHE A N 1 ATOM 457 C CA . PHE A 1 84 ? 33.246 44.646 20.272 1.00 15.36 ? 84 PHE A CA 1 ATOM 458 C C . PHE A 1 84 ? 32.862 46.110 20.203 1.00 14.51 ? 84 PHE A C 1 ATOM 459 O O . PHE A 1 84 ? 32.313 46.572 19.191 1.00 14.83 ? 84 PHE A O 1 ATOM 460 C CB . PHE A 1 84 ? 34.099 44.293 19.048 1.00 15.28 ? 84 PHE A CB 1 ATOM 461 C CG . PHE A 1 84 ? 34.733 42.969 19.169 1.00 15.35 ? 84 PHE A CG 1 ATOM 462 C CD1 . PHE A 1 84 ? 35.796 42.776 20.048 1.00 19.99 ? 84 PHE A CD1 1 ATOM 463 C CD2 . PHE A 1 84 ? 34.239 41.880 18.472 1.00 18.75 ? 84 PHE A CD2 1 ATOM 464 C CE1 . PHE A 1 84 ? 36.381 41.515 20.242 1.00 20.30 ? 84 PHE A CE1 1 ATOM 465 C CE2 . PHE A 1 84 ? 34.799 40.599 18.652 1.00 20.29 ? 84 PHE A CE2 1 ATOM 466 C CZ . PHE A 1 84 ? 35.883 40.418 19.542 1.00 21.01 ? 84 PHE A CZ 1 ATOM 467 N N . VAL A 1 85 ? 33.153 46.842 21.265 1.00 12.44 ? 85 VAL A N 1 ATOM 468 C CA . VAL A 1 85 ? 32.893 48.281 21.307 1.00 13.61 ? 85 VAL A CA 1 ATOM 469 C C . VAL A 1 85 ? 34.217 48.916 20.908 1.00 12.00 ? 85 VAL A C 1 ATOM 470 O O . VAL A 1 85 ? 35.268 48.739 21.571 1.00 13.08 ? 85 VAL A O 1 ATOM 471 C CB . VAL A 1 85 ? 32.451 48.738 22.709 1.00 12.68 ? 85 VAL A CB 1 ATOM 472 C CG1 . VAL A 1 85 ? 32.283 50.273 22.760 1.00 15.85 ? 85 VAL A CG1 1 ATOM 473 C CG2 . VAL A 1 85 ? 31.167 47.988 23.080 1.00 16.40 ? 85 VAL A CG2 1 ATOM 474 N N . VAL A 1 86 ? 34.177 49.644 19.784 1.00 12.34 ? 86 VAL A N 1 ATOM 475 C CA . VAL A 1 86 ? 35.398 50.191 19.190 1.00 12.62 ? 86 VAL A CA 1 ATOM 476 C C . VAL A 1 86 ? 35.461 51.720 19.280 1.00 11.44 ? 86 VAL A C 1 ATOM 477 O O . VAL A 1 86 ? 34.827 52.421 18.501 1.00 12.43 ? 86 VAL A O 1 ATOM 478 C CB . VAL A 1 86 ? 35.466 49.741 17.707 1.00 11.95 ? 86 VAL A CB 1 ATOM 479 C CG1 . VAL A 1 86 ? 36.771 50.308 17.072 1.00 13.96 ? 86 VAL A CG1 1 ATOM 480 C CG2 . VAL A 1 86 ? 35.398 48.175 17.593 1.00 13.73 ? 86 VAL A CG2 1 ATOM 481 N N . PRO A 1 87 ? 36.224 52.256 20.248 1.00 13.24 ? 87 PRO A N 1 ATOM 482 C CA . PRO A 1 87 ? 36.353 53.721 20.426 1.00 12.03 ? 87 PRO A CA 1 ATOM 483 C C . PRO A 1 87 ? 37.092 54.321 19.226 1.00 11.39 ? 87 PRO A C 1 ATOM 484 O O . PRO A 1 87 ? 38.102 53.740 18.725 1.00 12.03 ? 87 PRO A O 1 ATOM 485 C CB . PRO A 1 87 ? 37.181 53.865 21.721 1.00 12.94 ? 87 PRO A CB 1 ATOM 486 C CG . PRO A 1 87 ? 36.948 52.518 22.417 1.00 14.32 ? 87 PRO A CG 1 ATOM 487 C CD . PRO A 1 87 ? 36.945 51.518 21.291 1.00 12.92 ? 87 PRO A CD 1 ATOM 488 N N . HIS A 1 88 ? 36.572 55.451 18.777 1.00 11.33 ? 88 HIS A N 1 ATOM 489 C CA . HIS A 1 88 ? 37.167 56.134 17.601 1.00 12.47 ? 88 HIS A CA 1 ATOM 490 C C . HIS A 1 88 ? 36.914 57.609 17.680 1.00 13.80 ? 88 HIS A C 1 ATOM 491 O O . HIS A 1 88 ? 36.083 58.075 18.471 1.00 12.26 ? 88 HIS A O 1 ATOM 492 C CB . HIS A 1 88 ? 36.573 55.550 16.287 1.00 12.52 ? 88 HIS A CB 1 ATOM 493 C CG . HIS A 1 88 ? 35.135 55.876 16.045 1.00 13.11 ? 88 HIS A CG 1 ATOM 494 N ND1 . HIS A 1 88 ? 34.709 56.948 15.273 1.00 13.57 ? 88 HIS A ND1 1 ATOM 495 C CD2 . HIS A 1 88 ? 34.010 55.266 16.498 1.00 11.96 ? 88 HIS A CD2 1 ATOM 496 C CE1 . HIS A 1 88 ? 33.390 56.969 15.256 1.00 14.97 ? 88 HIS A CE1 1 ATOM 497 N NE2 . HIS A 1 88 ? 32.939 55.960 16.001 1.00 13.87 ? 88 HIS A NE2 1 ATOM 498 N N . SER A 1 89 ? 37.615 58.374 16.857 1.00 11.59 ? 89 SER A N 1 ATOM 499 C CA . SER A 1 89 ? 37.510 59.826 16.840 1.00 12.91 ? 89 SER A CA 1 ATOM 500 C C . SER A 1 89 ? 37.665 60.279 15.380 1.00 12.16 ? 89 SER A C 1 ATOM 501 O O . SER A 1 89 ? 38.748 60.063 14.812 1.00 12.83 ? 89 SER A O 1 ATOM 502 C CB . SER A 1 89 ? 38.645 60.377 17.697 1.00 13.76 ? 89 SER A CB 1 ATOM 503 O OG . SER A 1 89 ? 38.645 61.786 17.714 1.00 13.56 ? 89 SER A OG 1 ATOM 504 N N . HIS A 1 90 ? 36.609 60.841 14.801 1.00 11.77 ? 90 HIS A N 1 ATOM 505 C CA . HIS A 1 90 ? 36.660 61.288 13.404 1.00 12.48 ? 90 HIS A CA 1 ATOM 506 C C . HIS A 1 90 ? 37.355 62.645 13.340 1.00 11.85 ? 90 HIS A C 1 ATOM 507 O O . HIS A 1 90 ? 36.834 63.648 13.828 1.00 12.94 ? 90 HIS A O 1 ATOM 508 C CB . HIS A 1 90 ? 35.243 61.326 12.826 1.00 12.84 ? 90 HIS A CB 1 ATOM 509 C CG . HIS A 1 90 ? 35.207 61.622 11.360 1.00 11.93 ? 90 HIS A CG 1 ATOM 510 N ND1 . HIS A 1 90 ? 35.829 60.832 10.412 1.00 12.86 ? 90 HIS A ND1 1 ATOM 511 C CD2 . HIS A 1 90 ? 34.639 62.640 10.700 1.00 12.25 ? 90 HIS A CD2 1 ATOM 512 C CE1 . HIS A 1 90 ? 35.650 61.379 9.217 1.00 12.11 ? 90 HIS A CE1 1 ATOM 513 N NE2 . HIS A 1 90 ? 34.937 62.480 9.361 1.00 12.87 ? 90 HIS A NE2 1 ATOM 514 N N . ASN A 1 91 ? 38.538 62.669 12.732 1.00 12.54 ? 91 ASN A N 1 ATOM 515 C CA . ASN A 1 91 ? 39.318 63.902 12.672 1.00 12.94 ? 91 ASN A CA 1 ATOM 516 C C . ASN A 1 91 ? 39.485 64.379 11.240 1.00 14.94 ? 91 ASN A C 1 ATOM 517 O O . ASN A 1 91 ? 40.362 63.875 10.486 1.00 16.62 ? 91 ASN A O 1 ATOM 518 C CB . ASN A 1 91 ? 40.710 63.676 13.274 1.00 13.13 ? 91 ASN A CB 1 ATOM 519 C CG . ASN A 1 91 ? 40.686 63.554 14.766 1.00 14.30 ? 91 ASN A CG 1 ATOM 520 O OD1 . ASN A 1 91 ? 40.085 62.615 15.314 1.00 15.90 ? 91 ASN A OD1 1 ATOM 521 N ND2 . ASN A 1 91 ? 41.340 64.450 15.435 1.00 11.33 ? 91 ASN A ND2 1 ATOM 522 N N . ASP A 1 92 ? 38.713 65.371 10.869 1.00 11.33 ? 92 ASP A N 1 ATOM 523 C CA . ASP A 1 92 ? 38.810 65.885 9.504 1.00 12.92 ? 92 ASP A CA 1 ATOM 524 C C . ASP A 1 92 ? 40.056 66.715 9.292 1.00 12.86 ? 92 ASP A C 1 ATOM 525 O O . ASP A 1 92 ? 40.286 67.654 10.051 1.00 13.67 ? 92 ASP A O 1 ATOM 526 C CB . ASP A 1 92 ? 37.635 66.806 9.249 1.00 11.83 ? 92 ASP A CB 1 ATOM 527 C CG . ASP A 1 92 ? 36.318 66.079 9.248 1.00 12.31 ? 92 ASP A CG 1 ATOM 528 O OD1 . ASP A 1 92 ? 36.201 65.154 8.444 1.00 12.74 ? 92 ASP A OD1 1 ATOM 529 O OD2 . ASP A 1 92 ? 35.394 66.453 10.041 1.00 14.82 ? 92 ASP A OD2 1 ATOM 530 N N . PRO A 1 93 ? 40.899 66.403 8.289 1.00 12.37 ? 93 PRO A N 1 ATOM 531 C CA . PRO A 1 93 ? 42.129 67.174 7.983 1.00 12.09 ? 93 PRO A CA 1 ATOM 532 C C . PRO A 1 93 ? 41.721 68.453 7.221 1.00 13.27 ? 93 PRO A C 1 ATOM 533 O O . PRO A 1 93 ? 42.071 68.657 6.033 1.00 14.90 ? 93 PRO A O 1 ATOM 534 C CB . PRO A 1 93 ? 42.958 66.211 7.113 1.00 13.27 ? 93 PRO A CB 1 ATOM 535 C CG . PRO A 1 93 ? 42.426 64.830 7.455 1.00 15.40 ? 93 PRO A CG 1 ATOM 536 C CD . PRO A 1 93 ? 40.901 65.116 7.569 1.00 12.50 ? 93 PRO A CD 1 ATOM 537 N N . GLY A 1 94 ? 40.980 69.302 7.933 1.00 12.62 ? 94 GLY A N 1 ATOM 538 C CA . GLY A 1 94 ? 40.427 70.539 7.396 1.00 12.79 ? 94 GLY A CA 1 ATOM 539 C C . GLY A 1 94 ? 38.932 70.363 7.134 1.00 13.67 ? 94 GLY A C 1 ATOM 540 O O . GLY A 1 94 ? 38.489 69.312 6.621 1.00 14.96 ? 94 GLY A O 1 ATOM 541 N N . TRP A 1 95 ? 38.138 71.348 7.536 1.00 14.59 ? 95 TRP A N 1 ATOM 542 C CA . TRP A 1 95 ? 36.707 71.352 7.254 1.00 13.38 ? 95 TRP A CA 1 ATOM 543 C C . TRP A 1 95 ? 36.206 72.736 7.700 1.00 14.51 ? 95 TRP A C 1 ATOM 544 O O . TRP A 1 95 ? 36.161 73.653 6.885 1.00 14.18 ? 95 TRP A O 1 ATOM 545 C CB . TRP A 1 95 ? 35.957 70.206 7.965 1.00 13.01 ? 95 TRP A CB 1 ATOM 546 C CG . TRP A 1 95 ? 34.459 70.313 7.654 1.00 14.56 ? 95 TRP A CG 1 ATOM 547 C CD1 . TRP A 1 95 ? 33.871 70.700 6.460 1.00 12.85 ? 95 TRP A CD1 1 ATOM 548 C CD2 . TRP A 1 95 ? 33.381 70.003 8.533 1.00 14.61 ? 95 TRP A CD2 1 ATOM 549 N NE1 . TRP A 1 95 ? 32.492 70.646 6.564 1.00 14.17 ? 95 TRP A NE1 1 ATOM 550 C CE2 . TRP A 1 95 ? 32.173 70.212 7.828 1.00 13.72 ? 95 TRP A CE2 1 ATOM 551 C CE3 . TRP A 1 95 ? 33.323 69.550 9.858 1.00 14.56 ? 95 TRP A CE3 1 ATOM 552 C CZ2 . TRP A 1 95 ? 30.908 69.975 8.404 1.00 14.55 ? 95 TRP A CZ2 1 ATOM 553 C CZ3 . TRP A 1 95 ? 32.062 69.313 10.431 1.00 18.10 ? 95 TRP A CZ3 1 ATOM 554 C CH2 . TRP A 1 95 ? 30.874 69.529 9.690 1.00 17.28 ? 95 TRP A CH2 1 ATOM 555 N N . ILE A 1 96 ? 35.865 72.879 8.988 1.00 14.97 ? 96 ILE A N 1 ATOM 556 C CA . ILE A 1 96 ? 35.421 74.147 9.614 1.00 16.49 ? 96 ILE A CA 1 ATOM 557 C C . ILE A 1 96 ? 36.646 74.955 10.053 1.00 14.55 ? 96 ILE A C 1 ATOM 558 O O . ILE A 1 96 ? 36.566 76.177 10.220 1.00 18.75 ? 96 ILE A O 1 ATOM 559 C CB . ILE A 1 96 ? 34.573 73.885 10.908 1.00 20.04 ? 96 ILE A CB 1 ATOM 560 C CG1 . ILE A 1 96 ? 33.351 73.089 10.569 1.00 24.63 ? 96 ILE A CG1 1 ATOM 561 C CG2 . ILE A 1 96 ? 34.149 75.191 11.559 1.00 22.95 ? 96 ILE A CG2 1 ATOM 562 C CD1 . ILE A 1 96 ? 32.782 73.552 9.265 1.00 20.52 ? 96 ILE A CD1 1 ATOM 563 N N . GLN A 1 97 ? 37.764 74.270 10.260 1.00 13.33 ? 97 GLN A N 1 ATOM 564 C CA . GLN A 1 97 ? 39.035 74.903 10.609 1.00 13.05 ? 97 GLN A CA 1 ATOM 565 C C . GLN A 1 97 ? 40.063 74.279 9.660 1.00 12.60 ? 97 GLN A C 1 ATOM 566 O O . GLN A 1 97 ? 39.769 73.287 8.989 1.00 13.02 ? 97 GLN A O 1 ATOM 567 C CB . GLN A 1 97 ? 39.455 74.601 12.057 1.00 15.59 ? 97 GLN A CB 1 ATOM 568 C CG . GLN A 1 97 ? 38.424 74.980 13.143 1.00 16.08 ? 97 GLN A CG 1 ATOM 569 C CD A GLN A 1 97 ? 38.991 74.843 14.551 0.50 17.87 ? 97 GLN A CD 1 ATOM 570 C CD B GLN A 1 97 ? 38.783 76.617 13.202 0.50 20.00 ? 97 GLN A CD 1 ATOM 571 O OE1 A GLN A 1 97 ? 40.053 75.377 14.860 0.50 21.66 ? 97 GLN A OE1 1 ATOM 572 O OE1 B GLN A 1 97 ? 38.172 77.398 12.486 0.50 23.33 ? 97 GLN A OE1 1 ATOM 573 N NE2 A GLN A 1 97 ? 38.279 74.133 15.408 0.50 21.86 ? 97 GLN A NE2 1 ATOM 574 N NE2 B GLN A 1 97 ? 39.704 77.017 14.065 0.50 20.10 ? 97 GLN A NE2 1 ATOM 575 N N . THR A 1 98 ? 41.246 74.865 9.551 1.00 12.12 ? 98 THR A N 1 ATOM 576 C CA . THR A 1 98 ? 42.285 74.301 8.690 1.00 12.37 ? 98 THR A CA 1 ATOM 577 C C . THR A 1 98 ? 42.901 73.112 9.409 1.00 13.24 ? 98 THR A C 1 ATOM 578 O O . THR A 1 98 ? 42.667 72.872 10.611 1.00 13.40 ? 98 THR A O 1 ATOM 579 C CB . THR A 1 98 ? 43.413 75.285 8.446 1.00 12.33 ? 98 THR A CB 1 ATOM 580 O OG1 . THR A 1 98 ? 44.036 75.584 9.712 1.00 13.44 ? 98 THR A OG1 1 ATOM 581 C CG2 . THR A 1 98 ? 42.902 76.582 7.783 1.00 12.83 ? 98 THR A CG2 1 ATOM 582 N N . PHE A 1 99 ? 43.676 72.326 8.681 1.00 12.82 ? 99 PHE A N 1 ATOM 583 C CA . PHE A 1 99 ? 44.396 71.211 9.261 1.00 11.84 ? 99 PHE A CA 1 ATOM 584 C C . PHE A 1 99 ? 45.194 71.670 10.474 1.00 12.11 ? 99 PHE A C 1 ATOM 585 O O . PHE A 1 99 ? 45.137 71.047 11.538 1.00 12.92 ? 99 PHE A O 1 ATOM 586 C CB . PHE A 1 99 ? 45.385 70.670 8.220 1.00 12.38 ? 99 PHE A CB 1 ATOM 587 C CG . PHE A 1 99 ? 46.241 69.553 8.721 1.00 12.68 ? 99 PHE A CG 1 ATOM 588 C CD1 . PHE A 1 99 ? 45.832 68.210 8.618 1.00 12.57 ? 99 PHE A CD1 1 ATOM 589 C CD2 . PHE A 1 99 ? 47.452 69.832 9.332 1.00 13.13 ? 99 PHE A CD2 1 ATOM 590 C CE1 . PHE A 1 99 ? 46.620 67.188 9.113 1.00 12.90 ? 99 PHE A CE1 1 ATOM 591 C CE2 . PHE A 1 99 ? 48.257 68.810 9.835 1.00 15.10 ? 99 PHE A CE2 1 ATOM 592 C CZ . PHE A 1 99 ? 47.837 67.480 9.724 1.00 13.67 ? 99 PHE A CZ 1 ATOM 593 N N . GLU A 1 100 ? 45.957 72.750 10.330 1.00 13.10 ? 100 GLU A N 1 ATOM 594 C CA . GLU A 1 100 ? 46.799 73.154 11.441 1.00 13.49 ? 100 GLU A CA 1 ATOM 595 C C . GLU A 1 100 ? 45.991 73.682 12.617 1.00 13.06 ? 100 GLU A C 1 ATOM 596 O O . GLU A 1 100 ? 46.372 73.414 13.764 1.00 14.11 ? 100 GLU A O 1 ATOM 597 C CB . GLU A 1 100 ? 47.834 74.188 10.959 1.00 13.78 ? 100 GLU A CB 1 ATOM 598 C CG . GLU A 1 100 ? 48.868 74.569 12.042 1.00 16.75 ? 100 GLU A CG 1 ATOM 599 C CD . GLU A 1 100 ? 49.710 73.416 12.547 1.00 17.84 ? 100 GLU A CD 1 ATOM 600 O OE1 . GLU A 1 100 ? 49.870 72.386 11.866 1.00 17.31 ? 100 GLU A OE1 1 ATOM 601 O OE2 . GLU A 1 100 ? 50.325 73.574 13.645 1.00 20.11 ? 100 GLU A OE2 1 ATOM 602 N N . GLU A 1 101 ? 44.894 74.386 12.356 1.00 13.35 ? 101 GLU A N 1 ATOM 603 C CA . GLU A 1 101 ? 44.031 74.890 13.426 1.00 14.10 ? 101 GLU A CA 1 ATOM 604 C C . GLU A 1 101 ? 43.424 73.727 14.187 1.00 14.41 ? 101 GLU A C 1 ATOM 605 O O . GLU A 1 101 ? 43.442 73.729 15.435 1.00 14.65 ? 101 GLU A O 1 ATOM 606 C CB . GLU A 1 101 ? 42.895 75.742 12.865 1.00 15.46 ? 101 GLU A CB 1 ATOM 607 C CG . GLU A 1 101 ? 43.318 77.146 12.413 1.00 20.11 ? 101 GLU A CG 1 ATOM 608 C CD . GLU A 1 101 ? 42.234 77.904 11.601 1.00 23.98 ? 101 GLU A CD 1 ATOM 609 O OE1 . GLU A 1 101 ? 41.289 77.318 11.011 1.00 18.97 ? 101 GLU A OE1 1 ATOM 610 O OE2 . GLU A 1 101 ? 42.353 79.148 11.525 1.00 28.40 ? 101 GLU A OE2 1 ATOM 611 N N . TYR A 1 102 ? 42.856 72.748 13.502 1.00 13.10 ? 102 TYR A N 1 ATOM 612 C CA . TYR A 1 102 ? 42.328 71.580 14.224 1.00 13.53 ? 102 TYR A CA 1 ATOM 613 C C . TYR A 1 102 ? 43.437 70.860 14.982 1.00 14.96 ? 102 TYR A C 1 ATOM 614 O O . TYR A 1 102 ? 43.205 70.341 16.097 1.00 14.29 ? 102 TYR A O 1 ATOM 615 C CB . TYR A 1 102 ? 41.729 70.536 13.279 1.00 14.64 ? 102 TYR A CB 1 ATOM 616 C CG . TYR A 1 102 ? 40.340 70.824 12.787 1.00 14.31 ? 102 TYR A CG 1 ATOM 617 C CD1 . TYR A 1 102 ? 39.276 71.061 13.675 1.00 14.80 ? 102 TYR A CD1 1 ATOM 618 C CD2 . TYR A 1 102 ? 40.049 70.685 11.429 1.00 15.20 ? 102 TYR A CD2 1 ATOM 619 C CE1 . TYR A 1 102 ? 37.938 71.146 13.189 1.00 14.60 ? 102 TYR A CE1 1 ATOM 620 C CE2 . TYR A 1 102 ? 38.761 70.744 10.950 1.00 14.17 ? 102 TYR A CE2 1 ATOM 621 C CZ . TYR A 1 102 ? 37.703 70.974 11.831 1.00 13.86 ? 102 TYR A CZ 1 ATOM 622 O OH . TYR A 1 102 ? 36.414 70.988 11.361 1.00 15.31 ? 102 TYR A OH 1 ATOM 623 N N . TYR A 1 103 ? 44.618 70.726 14.390 1.00 13.17 ? 103 TYR A N 1 ATOM 624 C CA . TYR A 1 103 ? 45.688 70.040 15.092 1.00 14.67 ? 103 TYR A CA 1 ATOM 625 C C . TYR A 1 103 ? 46.003 70.722 16.407 1.00 14.69 ? 103 TYR A C 1 ATOM 626 O O . TYR A 1 103 ? 46.139 70.068 17.413 1.00 15.15 ? 103 TYR A O 1 ATOM 627 C CB . TYR A 1 103 ? 46.961 69.993 14.260 1.00 13.54 ? 103 TYR A CB 1 ATOM 628 C CG . TYR A 1 103 ? 48.102 69.369 15.001 1.00 15.16 ? 103 TYR A CG 1 ATOM 629 C CD1 . TYR A 1 103 ? 48.141 67.988 15.269 1.00 14.94 ? 103 TYR A CD1 1 ATOM 630 C CD2 . TYR A 1 103 ? 49.151 70.178 15.476 1.00 14.98 ? 103 TYR A CD2 1 ATOM 631 C CE1 . TYR A 1 103 ? 49.194 67.430 15.988 1.00 15.09 ? 103 TYR A CE1 1 ATOM 632 C CE2 . TYR A 1 103 ? 50.199 69.624 16.199 1.00 15.65 ? 103 TYR A CE2 1 ATOM 633 C CZ . TYR A 1 103 ? 50.218 68.266 16.462 1.00 15.29 ? 103 TYR A CZ 1 ATOM 634 O OH . TYR A 1 103 ? 51.211 67.709 17.290 1.00 18.56 ? 103 TYR A OH 1 ATOM 635 N N . GLN A 1 104 ? 46.123 72.040 16.376 1.00 14.27 ? 104 GLN A N 1 ATOM 636 C CA . GLN A 1 104 ? 46.474 72.781 17.603 1.00 15.46 ? 104 GLN A CA 1 ATOM 637 C C . GLN A 1 104 ? 45.383 72.800 18.635 1.00 17.85 ? 104 GLN A C 1 ATOM 638 O O . GLN A 1 104 ? 45.654 72.683 19.830 1.00 18.04 ? 104 GLN A O 1 ATOM 639 C CB . GLN A 1 104 ? 46.822 74.239 17.251 1.00 15.15 ? 104 GLN A CB 1 ATOM 640 C CG . GLN A 1 104 ? 48.153 74.357 16.511 1.00 16.26 ? 104 GLN A CG 1 ATOM 641 C CD . GLN A 1 104 ? 49.343 73.844 17.310 1.00 16.96 ? 104 GLN A CD 1 ATOM 642 O OE1 . GLN A 1 104 ? 49.374 73.955 18.542 1.00 19.10 ? 104 GLN A OE1 1 ATOM 643 N NE2 . GLN A 1 104 ? 50.329 73.306 16.622 1.00 18.53 ? 104 GLN A NE2 1 ATOM 644 N N . HIS A 1 105 ? 44.144 72.949 18.183 1.00 15.87 ? 105 HIS A N 1 ATOM 645 C CA . HIS A 1 105 ? 42.980 73.074 19.070 1.00 16.88 ? 105 HIS A CA 1 ATOM 646 C C . HIS A 1 105 ? 42.386 71.771 19.553 1.00 18.01 ? 105 HIS A C 1 ATOM 647 O O A HIS A 1 105 ? 41.817 71.713 20.639 0.50 19.10 ? 105 HIS A O 1 ATOM 648 O O B HIS A 1 105 ? 42.120 71.588 20.781 0.50 19.11 ? 105 HIS A O 1 ATOM 649 C CB . HIS A 1 105 ? 41.856 73.843 18.362 1.00 18.36 ? 105 HIS A CB 1 ATOM 650 C CG A HIS A 1 105 ? 42.252 75.205 17.878 0.50 20.06 ? 105 HIS A CG 1 ATOM 651 C CG B HIS A 1 105 ? 40.884 74.309 19.537 0.50 22.48 ? 105 HIS A CG 1 ATOM 652 N ND1 A HIS A 1 105 ? 41.583 75.851 16.862 0.50 24.52 ? 105 HIS A ND1 1 ATOM 653 N ND1 B HIS A 1 105 ? 39.820 73.520 19.913 0.50 25.64 ? 105 HIS A ND1 1 ATOM 654 C CD2 A HIS A 1 105 ? 43.241 76.042 18.270 0.50 23.22 ? 105 HIS A CD2 1 ATOM 655 C CD2 B HIS A 1 105 ? 40.761 75.463 20.236 0.50 27.02 ? 105 HIS A CD2 1 ATOM 656 C CE1 A HIS A 1 105 ? 42.147 77.026 16.646 0.50 23.95 ? 105 HIS A CE1 1 ATOM 657 C CE1 B HIS A 1 105 ? 39.082 74.167 20.800 0.50 26.92 ? 105 HIS A CE1 1 ATOM 658 N NE2 A HIS A 1 105 ? 43.155 77.166 17.487 0.50 23.30 ? 105 HIS A NE2 1 ATOM 659 N NE2 B HIS A 1 105 ? 39.633 75.350 21.013 0.50 27.38 ? 105 HIS A NE2 1 ATOM 660 N N . ASP A 1 106 ? 42.492 70.724 18.733 1.00 16.57 ? 106 ASP A N 1 ATOM 661 C CA . ASP A 1 106 ? 41.900 69.444 19.071 1.00 16.73 ? 106 ASP A CA 1 ATOM 662 C C . ASP A 1 106 ? 42.712 68.205 18.945 1.00 14.96 ? 106 ASP A C 1 ATOM 663 O O . ASP A 1 106 ? 42.908 67.503 19.936 1.00 16.09 ? 106 ASP A O 1 ATOM 664 C CB . ASP A 1 106 ? 40.623 69.256 18.225 1.00 20.00 ? 106 ASP A CB 1 ATOM 665 C CG . ASP A 1 106 ? 39.594 70.316 18.519 1.00 23.89 ? 106 ASP A CG 1 ATOM 666 O OD1 . ASP A 1 106 ? 38.866 70.144 19.509 1.00 23.07 ? 106 ASP A OD1 1 ATOM 667 O OD2 . ASP A 1 106 ? 39.544 71.315 17.767 1.00 26.55 ? 106 ASP A OD2 1 ATOM 668 N N . THR A 1 107 ? 43.223 67.926 17.746 1.00 14.77 ? 107 THR A N 1 ATOM 669 C CA . THR A 1 107 ? 43.872 66.646 17.505 1.00 13.64 ? 107 THR A CA 1 ATOM 670 C C . THR A 1 107 ? 45.120 66.375 18.314 1.00 13.79 ? 107 THR A C 1 ATOM 671 O O . THR A 1 107 ? 45.345 65.242 18.731 1.00 13.65 ? 107 THR A O 1 ATOM 672 C CB . THR A 1 107 ? 44.124 66.484 15.981 1.00 13.79 ? 107 THR A CB 1 ATOM 673 O OG1 . THR A 1 107 ? 42.894 66.705 15.299 1.00 14.55 ? 107 THR A OG1 1 ATOM 674 C CG2 . THR A 1 107 ? 44.678 65.078 15.677 1.00 14.49 ? 107 THR A CG2 1 ATOM 675 N N . LYS A 1 108 ? 45.926 67.403 18.578 1.00 13.38 ? 108 LYS A N 1 ATOM 676 C CA . LYS A 1 108 ? 47.121 67.081 19.347 1.00 13.07 ? 108 LYS A CA 1 ATOM 677 C C . LYS A 1 108 ? 46.768 66.639 20.757 1.00 13.36 ? 108 LYS A C 1 ATOM 678 O O . LYS A 1 108 ? 47.472 65.829 21.321 1.00 15.18 ? 108 LYS A O 1 ATOM 679 C CB . LYS A 1 108 ? 48.108 68.277 19.335 1.00 16.36 ? 108 LYS A CB 1 ATOM 680 C CG . LYS A 1 108 ? 47.826 69.432 20.252 1.00 18.44 ? 108 LYS A CG 1 ATOM 681 C CD . LYS A 1 108 ? 48.928 70.462 20.074 1.00 20.96 ? 108 LYS A CD 1 ATOM 682 C CE . LYS A 1 108 ? 48.728 71.618 21.012 1.00 22.07 ? 108 LYS A CE 1 ATOM 683 N NZ . LYS A 1 108 ? 49.886 72.572 20.939 1.00 25.03 ? 108 LYS A NZ 1 ATOM 684 N N . HIS A 1 109 ? 45.672 67.171 21.273 1.00 13.92 ? 109 HIS A N 1 ATOM 685 C CA . HIS A 1 109 ? 45.209 66.794 22.624 1.00 14.24 ? 109 HIS A CA 1 ATOM 686 C C . HIS A 1 109 ? 44.571 65.424 22.599 1.00 15.36 ? 109 HIS A C 1 ATOM 687 O O . HIS A 1 109 ? 44.795 64.626 23.509 1.00 14.91 ? 109 HIS A O 1 ATOM 688 C CB . HIS A 1 109 ? 44.222 67.810 23.126 1.00 14.32 ? 109 HIS A CB 1 ATOM 689 C CG . HIS A 1 109 ? 44.778 69.184 23.180 1.00 18.21 ? 109 HIS A CG 1 ATOM 690 N ND1 . HIS A 1 109 ? 45.810 69.523 24.033 1.00 23.03 ? 109 HIS A ND1 1 ATOM 691 C CD2 . HIS A 1 109 ? 44.484 70.289 22.460 1.00 22.08 ? 109 HIS A CD2 1 ATOM 692 C CE1 . HIS A 1 109 ? 46.126 70.790 23.833 1.00 21.56 ? 109 HIS A CE1 1 ATOM 693 N NE2 . HIS A 1 109 ? 45.337 71.277 22.885 1.00 22.92 ? 109 HIS A NE2 1 ATOM 694 N N . ILE A 1 110 ? 43.784 65.120 21.562 1.00 14.11 ? 110 ILE A N 1 ATOM 695 C CA . ILE A 1 110 ? 43.203 63.783 21.448 1.00 13.75 ? 110 ILE A CA 1 ATOM 696 C C . ILE A 1 110 ? 44.314 62.729 21.441 1.00 14.27 ? 110 ILE A C 1 ATOM 697 O O . ILE A 1 110 ? 44.237 61.716 22.141 1.00 14.87 ? 110 ILE A O 1 ATOM 698 C CB . ILE A 1 110 ? 42.379 63.686 20.118 1.00 12.08 ? 110 ILE A CB 1 ATOM 699 C CG1 . ILE A 1 110 ? 41.156 64.586 20.208 1.00 13.06 ? 110 ILE A CG1 1 ATOM 700 C CG2 . ILE A 1 110 ? 42.033 62.217 19.806 1.00 14.28 ? 110 ILE A CG2 1 ATOM 701 C CD1 . ILE A 1 110 ? 40.416 64.841 18.835 1.00 14.06 ? 110 ILE A CD1 1 ATOM 702 N N . LEU A 1 111 ? 45.333 62.933 20.624 1.00 13.14 ? 111 LEU A N 1 ATOM 703 C CA . LEU A 1 111 ? 46.390 61.959 20.548 1.00 12.43 ? 111 LEU A CA 1 ATOM 704 C C . LEU A 1 111 ? 47.252 61.873 21.795 1.00 13.22 ? 111 LEU A C 1 ATOM 705 O O . LEU A 1 111 ? 47.667 60.787 22.181 1.00 14.52 ? 111 LEU A O 1 ATOM 706 C CB . LEU A 1 111 ? 47.265 62.221 19.293 1.00 13.77 ? 111 LEU A CB 1 ATOM 707 C CG . LEU A 1 111 ? 46.498 61.871 18.003 1.00 13.14 ? 111 LEU A CG 1 ATOM 708 C CD1 . LEU A 1 111 ? 47.361 62.356 16.825 1.00 13.22 ? 111 LEU A CD1 1 ATOM 709 C CD2 . LEU A 1 111 ? 46.215 60.380 17.919 1.00 16.59 ? 111 LEU A CD2 1 ATOM 710 N N . SER A 1 112 ? 47.545 63.017 22.388 1.00 13.97 ? 112 SER A N 1 ATOM 711 C CA . SER A 1 112 ? 48.366 63.012 23.598 1.00 14.76 ? 112 SER A CA 1 ATOM 712 C C . SER A 1 112 ? 47.581 62.323 24.726 1.00 16.50 ? 112 SER A C 1 ATOM 713 O O . SER A 1 112 ? 48.144 61.506 25.480 1.00 16.75 ? 112 SER A O 1 ATOM 714 C CB A SER A 1 112 ? 48.730 64.444 23.966 0.50 15.88 ? 112 SER A CB 1 ATOM 715 C CB B SER A 1 112 ? 48.547 64.500 24.050 0.50 19.58 ? 112 SER A CB 1 ATOM 716 O OG A SER A 1 112 ? 49.434 64.479 25.191 0.50 16.05 ? 112 SER A OG 1 ATOM 717 O OG B SER A 1 112 ? 49.300 65.183 23.087 0.50 22.53 ? 112 SER A OG 1 ATOM 718 N N . ASN A 1 113 ? 46.288 62.614 24.828 1.00 15.98 ? 113 ASN A N 1 ATOM 719 C CA . ASN A 1 113 ? 45.508 61.949 25.867 1.00 15.16 ? 113 ASN A CA 1 ATOM 720 C C . ASN A 1 113 ? 45.248 60.494 25.520 1.00 16.94 ? 113 ASN A C 1 ATOM 721 O O . ASN A 1 113 ? 45.161 59.663 26.432 1.00 16.04 ? 113 ASN A O 1 ATOM 722 C CB . ASN A 1 113 ? 44.254 62.740 26.205 1.00 16.38 ? 113 ASN A CB 1 ATOM 723 C CG . ASN A 1 113 ? 44.634 64.080 26.835 1.00 18.72 ? 113 ASN A CG 1 ATOM 724 O OD1 . ASN A 1 113 ? 45.727 64.194 27.443 1.00 23.44 ? 113 ASN A OD1 1 ATOM 725 N ND2 . ASN A 1 113 ? 43.799 65.084 26.677 1.00 20.70 ? 113 ASN A ND2 1 ATOM 726 N N . ALA A 1 114 ? 45.152 60.134 24.230 1.00 15.61 ? 114 ALA A N 1 ATOM 727 C CA . ALA A 1 114 ? 44.988 58.718 23.891 1.00 16.71 ? 114 ALA A CA 1 ATOM 728 C C . ALA A 1 114 ? 46.240 57.968 24.366 1.00 15.59 ? 114 ALA A C 1 ATOM 729 O O . ALA A 1 114 ? 46.167 56.839 24.901 1.00 17.07 ? 114 ALA A O 1 ATOM 730 C CB . ALA A 1 114 ? 44.860 58.543 22.372 1.00 14.58 ? 114 ALA A CB 1 ATOM 731 N N . LEU A 1 115 ? 47.425 58.557 24.150 1.00 15.87 ? 115 LEU A N 1 ATOM 732 C CA . LEU A 1 115 ? 48.644 57.892 24.558 1.00 16.88 ? 115 LEU A CA 1 ATOM 733 C C . LEU A 1 115 ? 48.650 57.647 26.063 1.00 18.66 ? 115 LEU A C 1 ATOM 734 O O . LEU A 1 115 ? 48.933 56.543 26.524 1.00 18.97 ? 115 LEU A O 1 ATOM 735 C CB . LEU A 1 115 ? 49.879 58.715 24.168 1.00 17.95 ? 115 LEU A CB 1 ATOM 736 C CG . LEU A 1 115 ? 51.246 58.158 24.610 1.00 19.16 ? 115 LEU A CG 1 ATOM 737 C CD1 . LEU A 1 115 ? 51.472 56.746 24.145 1.00 22.58 ? 115 LEU A CD1 1 ATOM 738 C CD2 . LEU A 1 115 ? 52.310 59.059 24.029 1.00 19.69 ? 115 LEU A CD2 1 ATOM 739 N N . ARG A 1 116 ? 48.289 58.674 26.802 1.00 17.98 ? 116 ARG A N 1 ATOM 740 C CA . ARG A 1 116 ? 48.279 58.529 28.253 1.00 18.61 ? 116 ARG A CA 1 ATOM 741 C C . ARG A 1 116 ? 47.214 57.528 28.731 1.00 18.14 ? 116 ARG A C 1 ATOM 742 O O . ARG A 1 116 ? 47.528 56.594 29.491 1.00 18.02 ? 116 ARG A O 1 ATOM 743 C CB . ARG A 1 116 ? 48.041 59.886 28.887 1.00 21.32 ? 116 ARG A CB 1 ATOM 744 C CG . ARG A 1 116 ? 47.577 59.812 30.367 1.00 25.87 ? 116 ARG A CG 1 ATOM 745 C CD . ARG A 1 116 ? 47.027 61.167 30.827 1.00 33.29 ? 116 ARG A CD 1 ATOM 746 N NE . ARG A 1 116 ? 46.500 61.146 32.194 1.00 36.08 ? 116 ARG A NE 1 ATOM 747 C CZ . ARG A 1 116 ? 46.062 62.233 32.828 1.00 38.62 ? 116 ARG A CZ 1 ATOM 748 N NH1 . ARG A 1 116 ? 46.091 63.412 32.211 1.00 38.49 ? 116 ARG A NH1 1 ATOM 749 N NH2 . ARG A 1 116 ? 45.611 62.148 34.079 1.00 40.42 ? 116 ARG A NH2 1 ATOM 750 N N . HIS A 1 117 ? 45.984 57.679 28.252 1.00 16.35 ? 117 HIS A N 1 ATOM 751 C CA . HIS A 1 117 ? 44.928 56.790 28.713 1.00 17.23 ? 117 HIS A CA 1 ATOM 752 C C . HIS A 1 117 ? 45.072 55.370 28.284 1.00 17.85 ? 117 HIS A C 1 ATOM 753 O O . HIS A 1 117 ? 44.760 54.487 29.058 1.00 18.05 ? 117 HIS A O 1 ATOM 754 C CB . HIS A 1 117 ? 43.568 57.337 28.355 1.00 19.35 ? 117 HIS A CB 1 ATOM 755 C CG . HIS A 1 117 ? 43.184 58.498 29.207 1.00 23.76 ? 117 HIS A CG 1 ATOM 756 N ND1 . HIS A 1 117 ? 42.609 58.345 30.458 1.00 21.54 ? 117 HIS A ND1 1 ATOM 757 C CD2 . HIS A 1 117 ? 43.404 59.823 29.045 1.00 25.32 ? 117 HIS A CD2 1 ATOM 758 C CE1 . HIS A 1 117 ? 42.503 59.538 31.030 1.00 24.32 ? 117 HIS A CE1 1 ATOM 759 N NE2 . HIS A 1 117 ? 42.979 60.450 30.198 1.00 26.63 ? 117 HIS A NE2 1 ATOM 760 N N . LEU A 1 118 ? 45.538 55.099 27.068 1.00 16.38 ? 118 LEU A N 1 ATOM 761 C CA . LEU A 1 118 ? 45.745 53.732 26.670 1.00 16.18 ? 118 LEU A CA 1 ATOM 762 C C . LEU A 1 118 ? 46.916 53.136 27.437 1.00 16.36 ? 118 LEU A C 1 ATOM 763 O O . LEU A 1 118 ? 46.858 51.983 27.901 1.00 18.08 ? 118 LEU A O 1 ATOM 764 C CB . LEU A 1 118 ? 45.956 53.657 25.135 1.00 15.69 ? 118 LEU A CB 1 ATOM 765 C CG . LEU A 1 118 ? 44.717 54.085 24.314 1.00 18.91 ? 118 LEU A CG 1 ATOM 766 C CD1 . LEU A 1 118 ? 45.134 54.242 22.818 1.00 18.04 ? 118 LEU A CD1 1 ATOM 767 C CD2 . LEU A 1 118 ? 43.611 53.083 24.484 1.00 17.26 ? 118 LEU A CD2 1 ATOM 768 N N . HIS A 1 119 ? 47.979 53.898 27.606 1.00 17.05 ? 119 HIS A N 1 ATOM 769 C CA . HIS A 1 119 ? 49.091 53.350 28.376 1.00 16.70 ? 119 HIS A CA 1 ATOM 770 C C . HIS A 1 119 ? 48.609 52.923 29.773 1.00 19.38 ? 119 HIS A C 1 ATOM 771 O O . HIS A 1 119 ? 48.910 51.817 30.227 1.00 20.40 ? 119 HIS A O 1 ATOM 772 C CB . HIS A 1 119 ? 50.186 54.410 28.525 1.00 20.64 ? 119 HIS A CB 1 ATOM 773 C CG . HIS A 1 119 ? 51.332 53.977 29.376 1.00 24.71 ? 119 HIS A CG 1 ATOM 774 N ND1 . HIS A 1 119 ? 51.475 54.376 30.690 1.00 30.76 ? 119 HIS A ND1 1 ATOM 775 C CD2 . HIS A 1 119 ? 52.374 53.156 29.114 1.00 28.95 ? 119 HIS A CD2 1 ATOM 776 C CE1 . HIS A 1 119 ? 52.559 53.817 31.200 1.00 30.03 ? 119 HIS A CE1 1 ATOM 777 N NE2 . HIS A 1 119 ? 53.124 53.073 30.265 1.00 30.25 ? 119 HIS A NE2 1 ATOM 778 N N . ASP A 1 120 ? 47.851 53.786 30.427 1.00 19.43 ? 120 ASP A N 1 ATOM 779 C CA . ASP A 1 120 ? 47.395 53.488 31.798 1.00 19.09 ? 120 ASP A CA 1 ATOM 780 C C . ASP A 1 120 ? 46.226 52.516 31.969 1.00 22.33 ? 120 ASP A C 1 ATOM 781 O O . ASP A 1 120 ? 45.952 52.102 33.097 1.00 21.28 ? 120 ASP A O 1 ATOM 782 C CB . ASP A 1 120 ? 47.008 54.787 32.501 1.00 20.36 ? 120 ASP A CB 1 ATOM 783 C CG . ASP A 1 120 ? 48.199 55.711 32.755 1.00 21.44 ? 120 ASP A CG 1 ATOM 784 O OD1 . ASP A 1 120 ? 49.363 55.279 32.634 1.00 24.18 ? 120 ASP A OD1 1 ATOM 785 O OD2 . ASP A 1 120 ? 47.962 56.879 33.091 1.00 25.46 ? 120 ASP A OD2 1 ATOM 786 N N . ASN A 1 121 ? 45.528 52.148 30.896 1.00 18.82 ? 121 ASN A N 1 ATOM 787 C CA . ASN A 1 121 ? 44.345 51.273 30.983 1.00 18.97 ? 121 ASN A CA 1 ATOM 788 C C . ASN A 1 121 ? 44.509 50.230 29.904 1.00 19.19 ? 121 ASN A C 1 ATOM 789 O O . ASN A 1 121 ? 43.961 50.354 28.811 1.00 19.02 ? 121 ASN A O 1 ATOM 790 C CB . ASN A 1 121 ? 43.095 52.104 30.755 1.00 18.24 ? 121 ASN A CB 1 ATOM 791 C CG . ASN A 1 121 ? 42.931 53.170 31.809 1.00 19.55 ? 121 ASN A CG 1 ATOM 792 O OD1 . ASN A 1 121 ? 43.320 54.347 31.615 1.00 21.68 ? 121 ASN A OD1 1 ATOM 793 N ND2 . ASN A 1 121 ? 42.361 52.775 32.953 1.00 19.91 ? 121 ASN A ND2 1 ATOM 794 N N . PRO A 1 122 ? 45.236 49.167 30.201 1.00 17.29 ? 122 PRO A N 1 ATOM 795 C CA . PRO A 1 122 ? 45.540 48.087 29.265 1.00 17.24 ? 122 PRO A CA 1 ATOM 796 C C . PRO A 1 122 ? 44.435 47.449 28.460 1.00 17.82 ? 122 PRO A C 1 ATOM 797 O O . PRO A 1 122 ? 44.739 46.925 27.352 1.00 20.21 ? 122 PRO A O 1 ATOM 798 C CB . PRO A 1 122 ? 46.301 47.073 30.121 1.00 19.51 ? 122 PRO A CB 1 ATOM 799 C CG . PRO A 1 122 ? 46.856 47.920 31.249 1.00 21.07 ? 122 PRO A CG 1 ATOM 800 C CD . PRO A 1 122 ? 45.723 48.826 31.561 1.00 19.08 ? 122 PRO A CD 1 ATOM 801 N N . GLU A 1 123 ? 43.189 47.457 28.954 1.00 16.41 ? 123 GLU A N 1 ATOM 802 C CA . GLU A 1 123 ? 42.095 46.857 28.180 1.00 17.71 ? 123 GLU A CA 1 ATOM 803 C C . GLU A 1 123 ? 41.382 47.855 27.271 1.00 17.18 ? 123 GLU A C 1 ATOM 804 O O . GLU A 1 123 ? 40.553 47.457 26.458 1.00 19.02 ? 123 GLU A O 1 ATOM 805 C CB . GLU A 1 123 ? 41.033 46.197 29.088 1.00 20.66 ? 123 GLU A CB 1 ATOM 806 C CG . GLU A 1 123 ? 41.535 45.089 30.027 1.00 28.34 ? 123 GLU A CG 1 ATOM 807 C CD . GLU A 1 123 ? 42.251 43.986 29.306 1.00 32.51 ? 123 GLU A CD 1 ATOM 808 O OE1 . GLU A 1 123 ? 41.685 43.445 28.326 1.00 35.99 ? 123 GLU A OE1 1 ATOM 809 O OE2 . GLU A 1 123 ? 43.388 43.651 29.722 1.00 39.12 ? 123 GLU A OE2 1 ATOM 810 N N . MET A 1 124 ? 41.655 49.151 27.428 1.00 15.64 ? 124 MET A N 1 ATOM 811 C CA . MET A 1 124 ? 41.035 50.175 26.588 1.00 16.28 ? 124 MET A CA 1 ATOM 812 C C . MET A 1 124 ? 41.676 50.075 25.189 1.00 17.73 ? 124 MET A C 1 ATOM 813 O O . MET A 1 124 ? 42.824 49.742 25.065 1.00 16.95 ? 124 MET A O 1 ATOM 814 C CB . MET A 1 124 ? 41.295 51.564 27.181 1.00 17.48 ? 124 MET A CB 1 ATOM 815 C CG . MET A 1 124 ? 40.565 52.711 26.476 1.00 18.29 ? 124 MET A CG 1 ATOM 816 S SD . MET A 1 124 ? 38.792 52.427 26.348 1.00 19.08 ? 124 MET A SD 1 ATOM 817 C CE . MET A 1 124 ? 38.317 53.969 25.521 1.00 19.71 ? 124 MET A CE 1 ATOM 818 N N . LYS A 1 125 ? 40.890 50.385 24.152 1.00 15.64 ? 125 LYS A N 1 ATOM 819 C CA . LYS A 1 125 ? 41.341 50.321 22.751 1.00 15.49 ? 125 LYS A CA 1 ATOM 820 C C . LYS A 1 125 ? 40.930 51.601 22.038 1.00 14.93 ? 125 LYS A C 1 ATOM 821 O O . LYS A 1 125 ? 40.065 52.368 22.520 1.00 14.74 ? 125 LYS A O 1 ATOM 822 C CB . LYS A 1 125 ? 40.629 49.163 22.063 1.00 15.98 ? 125 LYS A CB 1 ATOM 823 C CG . LYS A 1 125 ? 40.772 47.820 22.748 1.00 21.16 ? 125 LYS A CG 1 ATOM 824 C CD . LYS A 1 125 ? 42.174 47.333 22.579 1.00 23.38 ? 125 LYS A CD 1 ATOM 825 C CE . LYS A 1 125 ? 42.470 46.029 23.326 1.00 29.29 ? 125 LYS A CE 1 ATOM 826 N NZ . LYS A 1 125 ? 41.536 44.956 22.998 1.00 29.27 ? 125 LYS A NZ 1 ATOM 827 N N . PHE A 1 126 ? 41.560 51.850 20.874 1.00 13.02 ? 126 PHE A N 1 ATOM 828 C CA . PHE A 1 126 ? 41.250 53.069 20.115 1.00 12.24 ? 126 PHE A CA 1 ATOM 829 C C . PHE A 1 126 ? 41.727 52.814 18.664 1.00 12.27 ? 126 PHE A C 1 ATOM 830 O O . PHE A 1 126 ? 42.768 52.214 18.455 1.00 13.61 ? 126 PHE A O 1 ATOM 831 C CB . PHE A 1 126 ? 42.013 54.262 20.753 1.00 13.59 ? 126 PHE A CB 1 ATOM 832 C CG . PHE A 1 126 ? 41.624 55.625 20.237 1.00 12.20 ? 126 PHE A CG 1 ATOM 833 C CD1 . PHE A 1 126 ? 40.305 56.061 20.249 1.00 13.91 ? 126 PHE A CD1 1 ATOM 834 C CD2 . PHE A 1 126 ? 42.649 56.541 19.875 1.00 12.29 ? 126 PHE A CD2 1 ATOM 835 C CE1 . PHE A 1 126 ? 39.979 57.403 19.910 1.00 12.91 ? 126 PHE A CE1 1 ATOM 836 C CE2 . PHE A 1 126 ? 42.350 57.862 19.534 1.00 13.14 ? 126 PHE A CE2 1 ATOM 837 C CZ . PHE A 1 126 ? 41.032 58.306 19.542 1.00 12.64 ? 126 PHE A CZ 1 ATOM 838 N N . ILE A 1 127 ? 40.941 53.276 17.698 1.00 11.69 ? 127 ILE A N 1 ATOM 839 C CA . ILE A 1 127 ? 41.382 53.139 16.300 1.00 11.20 ? 127 ILE A CA 1 ATOM 840 C C . ILE A 1 127 ? 41.637 54.523 15.740 1.00 12.51 ? 127 ILE A C 1 ATOM 841 O O . ILE A 1 127 ? 41.013 55.504 16.170 1.00 13.27 ? 127 ILE A O 1 ATOM 842 C CB . ILE A 1 127 ? 40.358 52.392 15.396 1.00 12.74 ? 127 ILE A CB 1 ATOM 843 C CG1 . ILE A 1 127 ? 38.945 53.007 15.442 1.00 11.93 ? 127 ILE A CG1 1 ATOM 844 C CG2 . ILE A 1 127 ? 40.350 50.908 15.813 1.00 13.72 ? 127 ILE A CG2 1 ATOM 845 C CD1 . ILE A 1 127 ? 37.983 52.411 14.331 1.00 14.26 ? 127 ILE A CD1 1 ATOM 846 N N . TRP A 1 128 ? 42.578 54.601 14.804 1.00 12.40 ? 128 TRP A N 1 ATOM 847 C CA . TRP A 1 128 ? 42.964 55.871 14.202 1.00 12.80 ? 128 TRP A CA 1 ATOM 848 C C . TRP A 1 128 ? 43.087 55.743 12.689 1.00 12.31 ? 128 TRP A C 1 ATOM 849 O O . TRP A 1 128 ? 43.777 54.836 12.215 1.00 12.41 ? 128 TRP A O 1 ATOM 850 C CB . TRP A 1 128 ? 44.295 56.356 14.774 1.00 12.33 ? 128 TRP A CB 1 ATOM 851 C CG . TRP A 1 128 ? 44.595 57.775 14.430 1.00 12.81 ? 128 TRP A CG 1 ATOM 852 C CD1 . TRP A 1 128 ? 45.316 58.268 13.349 1.00 13.06 ? 128 TRP A CD1 1 ATOM 853 C CD2 . TRP A 1 128 ? 44.022 58.903 15.072 1.00 11.15 ? 128 TRP A CD2 1 ATOM 854 N NE1 . TRP A 1 128 ? 45.204 59.638 13.309 1.00 11.81 ? 128 TRP A NE1 1 ATOM 855 C CE2 . TRP A 1 128 ? 44.412 60.050 14.356 1.00 12.04 ? 128 TRP A CE2 1 ATOM 856 C CE3 . TRP A 1 128 ? 43.186 59.054 16.214 1.00 11.26 ? 128 TRP A CE3 1 ATOM 857 C CZ2 . TRP A 1 128 ? 44.014 61.327 14.729 1.00 13.00 ? 128 TRP A CZ2 1 ATOM 858 C CZ3 . TRP A 1 128 ? 42.791 60.305 16.575 1.00 12.54 ? 128 TRP A CZ3 1 ATOM 859 C CH2 . TRP A 1 128 ? 43.206 61.444 15.829 1.00 14.08 ? 128 TRP A CH2 1 ATOM 860 N N . ALA A 1 129 ? 42.474 56.694 11.977 1.00 13.16 ? 129 ALA A N 1 ATOM 861 C CA . ALA A 1 129 ? 42.471 56.649 10.514 1.00 13.37 ? 129 ALA A CA 1 ATOM 862 C C . ALA A 1 129 ? 43.377 57.613 9.771 1.00 12.42 ? 129 ALA A C 1 ATOM 863 O O . ALA A 1 129 ? 43.966 57.217 8.774 1.00 14.25 ? 129 ALA A O 1 ATOM 864 C CB . ALA A 1 129 ? 41.032 56.900 10.003 1.00 14.33 ? 129 ALA A CB 1 ATOM 865 N N . GLU A 1 130 ? 43.447 58.862 10.204 1.00 12.60 ? 130 GLU A N 1 ATOM 866 C CA . GLU A 1 130 ? 44.113 59.926 9.416 1.00 12.88 ? 130 GLU A CA 1 ATOM 867 C C . GLU A 1 130 ? 45.579 60.052 9.745 1.00 13.35 ? 130 GLU A C 1 ATOM 868 O O . GLU A 1 130 ? 45.972 60.681 10.739 1.00 12.50 ? 130 GLU A O 1 ATOM 869 C CB . GLU A 1 130 ? 43.358 61.243 9.657 1.00 15.08 ? 130 GLU A CB 1 ATOM 870 C CG . GLU A 1 130 ? 41.844 61.163 9.353 1.00 13.53 ? 130 GLU A CG 1 ATOM 871 C CD . GLU A 1 130 ? 40.990 60.719 10.551 1.00 17.98 ? 130 GLU A CD 1 ATOM 872 O OE1 . GLU A 1 130 ? 41.541 60.453 11.641 1.00 16.77 ? 130 GLU A OE1 1 ATOM 873 O OE2 . GLU A 1 130 ? 39.763 60.641 10.382 1.00 18.29 ? 130 GLU A OE2 1 ATOM 874 N N . ILE A 1 131 ? 46.428 59.511 8.874 1.00 11.91 ? 131 ILE A N 1 ATOM 875 C CA . ILE A 1 131 ? 47.855 59.539 9.165 1.00 12.53 ? 131 ILE A CA 1 ATOM 876 C C . ILE A 1 131 ? 48.480 60.922 9.011 1.00 13.56 ? 131 ILE A C 1 ATOM 877 O O . ILE A 1 131 ? 49.496 61.196 9.672 1.00 15.09 ? 131 ILE A O 1 ATOM 878 C CB . ILE A 1 131 ? 48.590 58.458 8.323 1.00 13.09 ? 131 ILE A CB 1 ATOM 879 C CG1 . ILE A 1 131 ? 47.936 57.097 8.606 1.00 12.01 ? 131 ILE A CG1 1 ATOM 880 C CG2 . ILE A 1 131 ? 50.072 58.401 8.680 1.00 14.38 ? 131 ILE A CG2 1 ATOM 881 C CD1 . ILE A 1 131 ? 47.738 56.720 10.121 1.00 15.25 ? 131 ILE A CD1 1 ATOM 882 N N . SER A 1 132 ? 47.898 61.814 8.223 1.00 11.03 ? 132 SER A N 1 ATOM 883 C CA . SER A 1 132 ? 48.440 63.173 8.140 1.00 10.90 ? 132 SER A CA 1 ATOM 884 C C . SER A 1 132 ? 48.530 63.773 9.559 1.00 13.43 ? 132 SER A C 1 ATOM 885 O O . SER A 1 132 ? 49.579 64.353 9.928 1.00 13.85 ? 132 SER A O 1 ATOM 886 C CB . SER A 1 132 ? 47.524 64.050 7.275 1.00 11.54 ? 132 SER A CB 1 ATOM 887 O OG . SER A 1 132 ? 46.163 64.005 7.722 1.00 12.82 ? 132 SER A OG 1 ATOM 888 N N . TYR A 1 133 ? 47.464 63.600 10.365 1.00 11.70 ? 133 TYR A N 1 ATOM 889 C CA . TYR A 1 133 ? 47.455 64.120 11.728 1.00 13.32 ? 133 TYR A CA 1 ATOM 890 C C . TYR A 1 133 ? 48.390 63.308 12.597 1.00 12.46 ? 133 TYR A C 1 ATOM 891 O O . TYR A 1 133 ? 49.073 63.909 13.448 1.00 13.45 ? 133 TYR A O 1 ATOM 892 C CB . TYR A 1 133 ? 46.076 64.023 12.375 1.00 13.13 ? 133 TYR A CB 1 ATOM 893 C CG . TYR A 1 133 ? 45.167 65.179 12.053 1.00 11.41 ? 133 TYR A CG 1 ATOM 894 C CD1 . TYR A 1 133 ? 45.548 66.495 12.312 1.00 12.70 ? 133 TYR A CD1 1 ATOM 895 C CD2 . TYR A 1 133 ? 43.911 64.952 11.478 1.00 11.29 ? 133 TYR A CD2 1 ATOM 896 C CE1 . TYR A 1 133 ? 44.695 67.547 12.023 1.00 12.80 ? 133 TYR A CE1 1 ATOM 897 C CE2 . TYR A 1 133 ? 43.031 65.990 11.178 1.00 11.22 ? 133 TYR A CE2 1 ATOM 898 C CZ . TYR A 1 133 ? 43.441 67.294 11.458 1.00 12.49 ? 133 TYR A CZ 1 ATOM 899 O OH . TYR A 1 133 ? 42.621 68.345 11.176 1.00 14.29 ? 133 TYR A OH 1 ATOM 900 N N . PHE A 1 134 ? 48.434 61.988 12.431 1.00 11.40 ? 134 PHE A N 1 ATOM 901 C CA . PHE A 1 134 ? 49.280 61.192 13.306 1.00 12.89 ? 134 PHE A CA 1 ATOM 902 C C . PHE A 1 134 ? 50.760 61.508 13.090 1.00 13.58 ? 134 PHE A C 1 ATOM 903 O O . PHE A 1 134 ? 51.535 61.641 14.071 1.00 15.28 ? 134 PHE A O 1 ATOM 904 C CB . PHE A 1 134 ? 49.014 59.689 13.119 1.00 12.41 ? 134 PHE A CB 1 ATOM 905 C CG . PHE A 1 134 ? 49.566 58.866 14.252 1.00 13.61 ? 134 PHE A CG 1 ATOM 906 C CD1 . PHE A 1 134 ? 48.838 58.666 15.446 1.00 13.59 ? 134 PHE A CD1 1 ATOM 907 C CD2 . PHE A 1 134 ? 50.841 58.367 14.154 1.00 15.33 ? 134 PHE A CD2 1 ATOM 908 C CE1 . PHE A 1 134 ? 49.440 57.946 16.522 1.00 13.18 ? 134 PHE A CE1 1 ATOM 909 C CE2 . PHE A 1 134 ? 51.435 57.656 15.198 1.00 16.26 ? 134 PHE A CE2 1 ATOM 910 C CZ . PHE A 1 134 ? 50.714 57.449 16.387 1.00 14.39 ? 134 PHE A CZ 1 ATOM 911 N N . ALA A 1 135 ? 51.154 61.707 11.820 1.00 14.33 ? 135 ALA A N 1 ATOM 912 C CA . ALA A 1 135 ? 52.545 62.005 11.517 1.00 14.90 ? 135 ALA A CA 1 ATOM 913 C C . ALA A 1 135 ? 52.867 63.419 12.059 1.00 15.22 ? 135 ALA A C 1 ATOM 914 O O . ALA A 1 135 ? 53.978 63.626 12.597 1.00 18.97 ? 135 ALA A O 1 ATOM 915 C CB . ALA A 1 135 ? 52.781 61.917 10.018 1.00 16.08 ? 135 ALA A CB 1 ATOM 916 N N . ARG A 1 136 ? 51.936 64.358 11.952 1.00 14.90 ? 136 ARG A N 1 ATOM 917 C CA . ARG A 1 136 ? 52.154 65.726 12.457 1.00 15.88 ? 136 ARG A CA 1 ATOM 918 C C . ARG A 1 136 ? 52.411 65.689 13.979 1.00 18.46 ? 136 ARG A C 1 ATOM 919 O O . ARG A 1 136 ? 53.237 66.442 14.508 1.00 20.79 ? 136 ARG A O 1 ATOM 920 C CB . ARG A 1 136 ? 50.926 66.599 12.138 1.00 16.66 ? 136 ARG A CB 1 ATOM 921 C CG . ARG A 1 136 ? 50.915 67.981 12.819 1.00 16.97 ? 136 ARG A CG 1 ATOM 922 C CD . ARG A 1 136 ? 51.809 68.980 12.090 1.00 19.41 ? 136 ARG A CD 1 ATOM 923 N NE . ARG A 1 136 ? 51.753 70.293 12.756 1.00 19.00 ? 136 ARG A NE 1 ATOM 924 C CZ . ARG A 1 136 ? 52.508 70.588 13.809 1.00 19.45 ? 136 ARG A CZ 1 ATOM 925 N NH1 . ARG A 1 136 ? 53.358 69.669 14.272 1.00 20.42 ? 136 ARG A NH1 1 ATOM 926 N NH2 . ARG A 1 136 ? 52.390 71.783 14.396 1.00 19.04 ? 136 ARG A NH2 1 ATOM 927 N N . PHE A 1 137 ? 51.702 64.800 14.672 1.00 16.74 ? 137 PHE A N 1 ATOM 928 C CA . PHE A 1 137 ? 51.810 64.635 16.111 1.00 15.60 ? 137 PHE A CA 1 ATOM 929 C C . PHE A 1 137 ? 53.088 63.914 16.516 1.00 17.02 ? 137 PHE A C 1 ATOM 930 O O . PHE A 1 137 ? 53.865 64.403 17.374 1.00 17.20 ? 137 PHE A O 1 ATOM 931 C CB . PHE A 1 137 ? 50.627 63.807 16.590 1.00 15.97 ? 137 PHE A CB 1 ATOM 932 C CG . PHE A 1 137 ? 50.623 63.550 18.074 1.00 16.91 ? 137 PHE A CG 1 ATOM 933 C CD1 . PHE A 1 137 ? 50.322 64.585 18.949 1.00 18.81 ? 137 PHE A CD1 1 ATOM 934 C CD2 . PHE A 1 137 ? 50.956 62.291 18.565 1.00 19.32 ? 137 PHE A CD2 1 ATOM 935 C CE1 . PHE A 1 137 ? 50.346 64.387 20.325 1.00 18.76 ? 137 PHE A CE1 1 ATOM 936 C CE2 . PHE A 1 137 ? 51.004 62.074 19.983 1.00 19.26 ? 137 PHE A CE2 1 ATOM 937 C CZ . PHE A 1 137 ? 50.690 63.137 20.836 1.00 17.33 ? 137 PHE A CZ 1 ATOM 938 N N . TYR A 1 138 ? 53.332 62.769 15.888 1.00 17.68 ? 138 TYR A N 1 ATOM 939 C CA . TYR A 1 138 ? 54.473 61.924 16.213 1.00 19.99 ? 138 TYR A CA 1 ATOM 940 C C . TYR A 1 138 ? 55.837 62.596 16.074 1.00 21.46 ? 138 TYR A C 1 ATOM 941 O O . TYR A 1 138 ? 56.741 62.366 16.902 1.00 21.70 ? 138 TYR A O 1 ATOM 942 C CB A TYR A 1 138 ? 54.424 60.644 15.369 0.50 20.27 ? 138 TYR A CB 1 ATOM 943 C CB B TYR A 1 138 ? 54.563 60.766 15.173 0.50 20.46 ? 138 TYR A CB 1 ATOM 944 C CG A TYR A 1 138 ? 55.402 59.578 15.813 0.50 17.95 ? 138 TYR A CG 1 ATOM 945 C CG B TYR A 1 138 ? 55.736 59.830 15.423 0.50 18.88 ? 138 TYR A CG 1 ATOM 946 C CD1 A TYR A 1 138 ? 55.094 58.710 16.862 0.50 17.63 ? 138 TYR A CD1 1 ATOM 947 C CD1 B TYR A 1 138 ? 55.619 58.768 16.313 0.50 18.82 ? 138 TYR A CD1 1 ATOM 948 C CD2 A TYR A 1 138 ? 56.620 59.428 15.166 0.50 17.18 ? 138 TYR A CD2 1 ATOM 949 C CD2 B TYR A 1 138 ? 56.947 59.995 14.746 0.50 18.15 ? 138 TYR A CD2 1 ATOM 950 C CE1 A TYR A 1 138 ? 55.989 57.708 17.252 0.50 16.72 ? 138 TYR A CE1 1 ATOM 951 C CE1 B TYR A 1 138 ? 56.688 57.884 16.527 0.50 19.69 ? 138 TYR A CE1 1 ATOM 952 C CE2 A TYR A 1 138 ? 57.524 58.432 15.540 0.50 16.13 ? 138 TYR A CE2 1 ATOM 953 C CE2 B TYR A 1 138 ? 58.017 59.105 14.953 0.50 17.47 ? 138 TYR A CE2 1 ATOM 954 C CZ A TYR A 1 138 ? 57.197 57.576 16.581 0.50 16.27 ? 138 TYR A CZ 1 ATOM 955 C CZ B TYR A 1 138 ? 57.871 58.069 15.839 0.50 19.91 ? 138 TYR A CZ 1 ATOM 956 O OH A TYR A 1 138 ? 58.074 56.571 16.924 0.50 18.02 ? 138 TYR A OH 1 ATOM 957 O OH B TYR A 1 138 ? 58.917 57.206 16.048 0.50 21.67 ? 138 TYR A OH 1 ATOM 958 N N . HIS A 1 139 ? 56.010 63.419 15.052 1.00 22.57 ? 139 HIS A N 1 ATOM 959 C CA . HIS A 1 139 ? 57.268 64.088 14.858 1.00 25.51 ? 139 HIS A CA 1 ATOM 960 C C . HIS A 1 139 ? 57.543 65.180 15.863 1.00 26.88 ? 139 HIS A C 1 ATOM 961 O O . HIS A 1 139 ? 58.690 65.637 15.982 1.00 29.74 ? 139 HIS A O 1 ATOM 962 C CB . HIS A 1 139 ? 57.374 64.545 13.408 1.00 26.22 ? 139 HIS A CB 1 ATOM 963 C CG . HIS A 1 139 ? 57.579 63.403 12.455 1.00 28.13 ? 139 HIS A CG 1 ATOM 964 N ND1 . HIS A 1 139 ? 58.677 62.569 12.526 1.00 30.20 ? 139 HIS A ND1 1 ATOM 965 C CD2 . HIS A 1 139 ? 56.806 62.930 11.444 1.00 25.15 ? 139 HIS A CD2 1 ATOM 966 C CE1 . HIS A 1 139 ? 58.575 61.632 11.598 1.00 30.27 ? 139 HIS A CE1 1 ATOM 967 N NE2 . HIS A 1 139 ? 57.452 61.829 10.924 1.00 28.39 ? 139 HIS A NE2 1 ATOM 968 N N . ASP A 1 140 ? 56.510 65.576 16.614 1.00 24.11 ? 140 ASP A N 1 ATOM 969 C CA . ASP A 1 140 ? 56.669 66.568 17.678 1.00 25.50 ? 140 ASP A CA 1 ATOM 970 C C . ASP A 1 140 ? 56.857 65.935 19.065 1.00 22.86 ? 140 ASP A C 1 ATOM 971 O O . ASP A 1 140 ? 57.064 66.637 20.061 1.00 25.71 ? 140 ASP A O 1 ATOM 972 C CB . ASP A 1 140 ? 55.480 67.488 17.713 1.00 25.39 ? 140 ASP A CB 1 ATOM 973 C CG . ASP A 1 140 ? 55.651 68.660 16.758 1.00 29.33 ? 140 ASP A CG 1 ATOM 974 O OD1 . ASP A 1 140 ? 56.532 68.570 15.867 1.00 33.44 ? 140 ASP A OD1 1 ATOM 975 O OD2 . ASP A 1 140 ? 54.923 69.648 16.900 1.00 30.28 ? 140 ASP A OD2 1 ATOM 976 N N . LEU A 1 141 ? 56.780 64.617 19.132 1.00 23.16 ? 141 LEU A N 1 ATOM 977 C CA . LEU A 1 141 ? 56.969 63.906 20.393 1.00 22.13 ? 141 LEU A CA 1 ATOM 978 C C . LEU A 1 141 ? 58.422 63.683 20.749 1.00 23.94 ? 141 LEU A C 1 ATOM 979 O O . LEU A 1 141 ? 59.263 63.502 19.884 1.00 24.27 ? 141 LEU A O 1 ATOM 980 C CB . LEU A 1 141 ? 56.358 62.503 20.340 1.00 23.46 ? 141 LEU A CB 1 ATOM 981 C CG . LEU A 1 141 ? 54.848 62.309 20.324 1.00 25.91 ? 141 LEU A CG 1 ATOM 982 C CD1 . LEU A 1 141 ? 54.546 60.791 20.331 1.00 22.77 ? 141 LEU A CD1 1 ATOM 983 C CD2 . LEU A 1 141 ? 54.215 62.998 21.545 1.00 25.28 ? 141 LEU A CD2 1 ATOM 984 N N . GLY A 1 142 ? 58.700 63.654 22.049 1.00 23.88 ? 142 GLY A N 1 ATOM 985 C CA . GLY A 1 142 ? 60.053 63.354 22.487 1.00 26.78 ? 142 GLY A CA 1 ATOM 986 C C . GLY A 1 142 ? 60.224 61.843 22.373 1.00 26.02 ? 142 GLY A C 1 ATOM 987 O O . GLY A 1 142 ? 59.219 61.107 22.285 1.00 27.02 ? 142 GLY A O 1 ATOM 988 N N . GLU A 1 143 ? 61.462 61.371 22.399 1.00 27.14 ? 143 GLU A N 1 ATOM 989 C CA . GLU A 1 143 ? 61.762 59.954 22.259 1.00 27.55 ? 143 GLU A CA 1 ATOM 990 C C . GLU A 1 143 ? 61.053 59.080 23.285 1.00 26.94 ? 143 GLU A C 1 ATOM 991 O O . GLU A 1 143 ? 60.582 57.989 22.976 1.00 26.18 ? 143 GLU A O 1 ATOM 992 C CB . GLU A 1 143 ? 63.275 59.742 22.338 1.00 30.83 ? 143 GLU A CB 1 ATOM 993 C CG . GLU A 1 143 ? 63.765 58.352 21.920 1.00 34.95 ? 143 GLU A CG 1 ATOM 994 C CD . GLU A 1 143 ? 63.372 57.978 20.489 1.00 39.95 ? 143 GLU A CD 1 ATOM 995 O OE1 . GLU A 1 143 ? 63.464 58.849 19.581 1.00 43.18 ? 143 GLU A OE1 1 ATOM 996 O OE2 . GLU A 1 143 ? 62.975 56.806 20.278 1.00 43.67 ? 143 GLU A OE2 1 ATOM 997 N N . ASN A 1 144 ? 60.959 59.548 24.510 1.00 26.64 ? 144 ASN A N 1 ATOM 998 C CA . ASN A 1 144 ? 60.304 58.750 25.533 1.00 29.63 ? 144 ASN A CA 1 ATOM 999 C C . ASN A 1 144 ? 58.847 58.424 25.100 1.00 26.47 ? 144 ASN A C 1 ATOM 1000 O O . ASN A 1 144 ? 58.408 57.269 25.152 1.00 26.11 ? 144 ASN A O 1 ATOM 1001 C CB . ASN A 1 144 ? 60.410 59.536 26.855 1.00 32.80 ? 144 ASN A CB 1 ATOM 1002 C CG . ASN A 1 144 ? 59.546 58.982 27.962 1.00 41.59 ? 144 ASN A CG 1 ATOM 1003 O OD1 . ASN A 1 144 ? 58.383 59.396 28.133 1.00 46.11 ? 144 ASN A OD1 1 ATOM 1004 N ND2 . ASN A 1 144 ? 60.102 58.040 28.740 1.00 44.60 ? 144 ASN A ND2 1 ATOM 1005 N N . LYS A 1 145 ? 58.127 59.435 24.634 1.00 25.70 ? 145 LYS A N 1 ATOM 1006 C CA . LYS A 1 145 ? 56.745 59.243 24.220 1.00 24.22 ? 145 LYS A CA 1 ATOM 1007 C C . LYS A 1 145 ? 56.646 58.470 22.909 1.00 23.09 ? 145 LYS A C 1 ATOM 1008 O O . LYS A 1 145 ? 55.688 57.717 22.732 1.00 21.55 ? 145 LYS A O 1 ATOM 1009 C CB . LYS A 1 145 ? 56.025 60.585 24.094 1.00 24.80 ? 145 LYS A CB 1 ATOM 1010 C CG . LYS A 1 145 ? 55.819 61.300 25.425 1.00 27.98 ? 145 LYS A CG 1 ATOM 1011 C CD . LYS A 1 145 ? 54.682 60.675 26.194 1.00 33.09 ? 145 LYS A CD 1 ATOM 1012 C CE . LYS A 1 145 ? 54.370 61.440 27.477 1.00 37.96 ? 145 LYS A CE 1 ATOM 1013 N NZ . LYS A 1 145 ? 55.343 61.118 28.553 1.00 40.78 ? 145 LYS A NZ 1 ATOM 1014 N N . LYS A 1 146 ? 57.603 58.661 21.996 1.00 24.09 ? 146 LYS A N 1 ATOM 1015 C CA . LYS A 1 146 ? 57.574 57.909 20.734 1.00 23.67 ? 146 LYS A CA 1 ATOM 1016 C C . LYS A 1 146 ? 57.628 56.435 21.087 1.00 23.18 ? 146 LYS A C 1 ATOM 1017 O O . LYS A 1 146 ? 56.913 55.612 20.516 1.00 21.31 ? 146 LYS A O 1 ATOM 1018 C CB . LYS A 1 146 ? 58.750 58.255 19.810 1.00 21.62 ? 146 LYS A CB 1 ATOM 1019 C CG . LYS A 1 146 ? 58.657 59.595 19.125 1.00 20.91 ? 146 LYS A CG 1 ATOM 1020 C CD . LYS A 1 146 ? 59.861 59.846 18.209 1.00 21.83 ? 146 LYS A CD 1 ATOM 1021 C CE . LYS A 1 146 ? 59.657 61.110 17.377 1.00 24.73 ? 146 LYS A CE 1 ATOM 1022 N NZ . LYS A 1 146 ? 60.898 61.495 16.725 1.00 30.16 ? 146 LYS A NZ 1 ATOM 1023 N N . LEU A 1 147 ? 58.462 56.090 22.058 1.00 23.94 ? 147 LEU A N 1 ATOM 1024 C CA . LEU A 1 147 ? 58.590 54.699 22.479 1.00 23.41 ? 147 LEU A CA 1 ATOM 1025 C C . LEU A 1 147 ? 57.297 54.179 23.134 1.00 21.86 ? 147 LEU A C 1 ATOM 1026 O O . LEU A 1 147 ? 56.879 53.040 22.867 1.00 21.83 ? 147 LEU A O 1 ATOM 1027 C CB . LEU A 1 147 ? 59.783 54.560 23.442 1.00 24.54 ? 147 LEU A CB 1 ATOM 1028 C CG . LEU A 1 147 ? 61.154 54.674 22.771 1.00 26.97 ? 147 LEU A CG 1 ATOM 1029 C CD1 . LEU A 1 147 ? 62.177 54.609 23.906 1.00 28.81 ? 147 LEU A CD1 1 ATOM 1030 C CD2 . LEU A 1 147 ? 61.410 53.552 21.763 1.00 28.13 ? 147 LEU A CD2 1 ATOM 1031 N N . GLN A 1 148 ? 56.673 54.997 23.981 1.00 20.55 ? 148 GLN A N 1 ATOM 1032 C CA . GLN A 1 148 ? 55.415 54.589 24.604 1.00 21.52 ? 148 GLN A CA 1 ATOM 1033 C C . GLN A 1 148 ? 54.369 54.399 23.494 1.00 20.17 ? 148 GLN A C 1 ATOM 1034 O O . GLN A 1 148 ? 53.578 53.470 23.551 1.00 21.82 ? 148 GLN A O 1 ATOM 1035 C CB . GLN A 1 148 ? 54.906 55.655 25.557 1.00 25.47 ? 148 GLN A CB 1 ATOM 1036 C CG . GLN A 1 148 ? 55.646 55.730 26.847 1.00 32.49 ? 148 GLN A CG 1 ATOM 1037 C CD . GLN A 1 148 ? 54.946 56.651 27.826 1.00 35.97 ? 148 GLN A CD 1 ATOM 1038 O OE1 . GLN A 1 148 ? 55.247 56.636 29.035 1.00 40.36 ? 148 GLN A OE1 1 ATOM 1039 N NE2 . GLN A 1 148 ? 54.014 57.470 27.320 1.00 36.65 ? 148 GLN A NE2 1 ATOM 1040 N N . MET A 1 149 ? 54.386 55.288 22.509 1.00 20.21 ? 149 MET A N 1 ATOM 1041 C CA . MET A 1 149 ? 53.406 55.175 21.420 1.00 20.39 ? 149 MET A CA 1 ATOM 1042 C C . MET A 1 149 ? 53.618 53.890 20.644 1.00 20.22 ? 149 MET A C 1 ATOM 1043 O O . MET A 1 149 ? 52.657 53.153 20.368 1.00 19.12 ? 149 MET A O 1 ATOM 1044 C CB . MET A 1 149 ? 53.526 56.366 20.479 1.00 18.69 ? 149 MET A CB 1 ATOM 1045 C CG . MET A 1 149 ? 52.481 56.371 19.348 1.00 19.31 ? 149 MET A CG 1 ATOM 1046 S SD . MET A 1 149 ? 50.797 56.627 19.956 1.00 21.11 ? 149 MET A SD 1 ATOM 1047 C CE . MET A 1 149 ? 50.682 58.398 20.004 1.00 25.01 ? 149 MET A CE 1 ATOM 1048 N N . LYS A 1 150 ? 54.871 53.608 20.291 1.00 19.47 ? 150 LYS A N 1 ATOM 1049 C CA . LYS A 1 150 ? 55.134 52.396 19.543 1.00 20.34 ? 150 LYS A CA 1 ATOM 1050 C C . LYS A 1 150 ? 54.681 51.178 20.323 1.00 18.96 ? 150 LYS A C 1 ATOM 1051 O O . LYS A 1 150 ? 54.223 50.203 19.739 1.00 21.21 ? 150 LYS A O 1 ATOM 1052 C CB . LYS A 1 150 ? 56.620 52.268 19.183 1.00 20.40 ? 150 LYS A CB 1 ATOM 1053 C CG . LYS A 1 150 ? 57.031 53.258 18.101 1.00 24.76 ? 150 LYS A CG 1 ATOM 1054 C CD . LYS A 1 150 ? 58.421 53.000 17.598 1.00 31.12 ? 150 LYS A CD 1 ATOM 1055 C CE . LYS A 1 150 ? 59.445 53.655 18.473 1.00 36.21 ? 150 LYS A CE 1 ATOM 1056 N NZ . LYS A 1 150 ? 60.769 53.690 17.766 1.00 38.00 ? 150 LYS A NZ 1 ATOM 1057 N N . SER A 1 151 ? 54.784 51.240 21.648 1.00 21.39 ? 151 SER A N 1 ATOM 1058 C CA . SER A 1 151 ? 54.386 50.122 22.491 1.00 22.09 ? 151 SER A CA 1 ATOM 1059 C C . SER A 1 151 ? 52.871 49.858 22.495 1.00 20.36 ? 151 SER A C 1 ATOM 1060 O O . SER A 1 151 ? 52.464 48.707 22.421 1.00 20.72 ? 151 SER A O 1 ATOM 1061 C CB . SER A 1 151 ? 54.898 50.323 23.931 1.00 23.18 ? 151 SER A CB 1 ATOM 1062 O OG A SER A 1 151 ? 54.113 51.266 24.633 0.50 24.49 ? 151 SER A OG 1 ATOM 1063 O OG B SER A 1 151 ? 54.746 49.088 24.625 0.50 23.02 ? 151 SER A OG 1 ATOM 1064 N N . ILE A 1 152 ? 52.041 50.904 22.567 1.00 19.25 ? 152 ILE A N 1 ATOM 1065 C CA . ILE A 1 152 ? 50.599 50.674 22.566 1.00 18.16 ? 152 ILE A CA 1 ATOM 1066 C C . ILE A 1 152 ? 50.124 50.262 21.164 1.00 17.87 ? 152 ILE A C 1 ATOM 1067 O O . ILE A 1 152 ? 49.059 49.687 21.028 1.00 19.77 ? 152 ILE A O 1 ATOM 1068 C CB . ILE A 1 152 ? 49.755 51.847 23.147 1.00 18.15 ? 152 ILE A CB 1 ATOM 1069 C CG1 . ILE A 1 152 ? 50.039 53.167 22.451 1.00 18.46 ? 152 ILE A CG1 1 ATOM 1070 C CG2 . ILE A 1 152 ? 50.069 51.983 24.659 1.00 20.50 ? 152 ILE A CG2 1 ATOM 1071 C CD1 . ILE A 1 152 ? 48.974 54.245 22.739 1.00 18.53 ? 152 ILE A CD1 1 ATOM 1072 N N . VAL A 1 153 ? 50.928 50.542 20.138 1.00 17.55 ? 153 VAL A N 1 ATOM 1073 C CA . VAL A 1 153 ? 50.569 50.078 18.794 1.00 18.16 ? 153 VAL A CA 1 ATOM 1074 C C . VAL A 1 153 ? 50.991 48.613 18.663 1.00 20.02 ? 153 VAL A C 1 ATOM 1075 O O . VAL A 1 153 ? 50.208 47.763 18.230 1.00 19.48 ? 153 VAL A O 1 ATOM 1076 C CB . VAL A 1 153 ? 51.237 50.953 17.726 1.00 17.68 ? 153 VAL A CB 1 ATOM 1077 C CG1 . VAL A 1 153 ? 51.062 50.329 16.319 1.00 18.90 ? 153 VAL A CG1 1 ATOM 1078 C CG2 . VAL A 1 153 ? 50.658 52.349 17.811 1.00 16.52 ? 153 VAL A CG2 1 ATOM 1079 N N . LYS A 1 154 ? 52.215 48.305 19.097 1.00 20.14 ? 154 LYS A N 1 ATOM 1080 C CA . LYS A 1 154 ? 52.681 46.929 19.027 1.00 20.49 ? 154 LYS A CA 1 ATOM 1081 C C . LYS A 1 154 ? 51.799 45.972 19.846 1.00 20.35 ? 154 LYS A C 1 ATOM 1082 O O . LYS A 1 154 ? 51.545 44.845 19.401 1.00 23.36 ? 154 LYS A O 1 ATOM 1083 C CB . LYS A 1 154 ? 54.133 46.862 19.501 1.00 23.05 ? 154 LYS A CB 1 ATOM 1084 C CG . LYS A 1 154 ? 54.800 45.530 19.183 1.00 28.78 ? 154 LYS A CG 1 ATOM 1085 C CD . LYS A 1 154 ? 56.253 45.563 19.624 1.00 34.71 ? 154 LYS A CD 1 ATOM 1086 C CE . LYS A 1 154 ? 56.368 45.903 21.116 1.00 40.15 ? 154 LYS A CE 1 ATOM 1087 N NZ . LYS A 1 154 ? 55.648 44.905 21.993 1.00 44.43 ? 154 LYS A NZ 1 ATOM 1088 N N . ASN A 1 155 ? 51.324 46.407 21.017 1.00 21.50 ? 155 ASN A N 1 ATOM 1089 C CA . ASN A 1 155 ? 50.461 45.551 21.858 1.00 21.26 ? 155 ASN A CA 1 ATOM 1090 C C . ASN A 1 155 ? 48.975 45.514 21.436 1.00 22.30 ? 155 ASN A C 1 ATOM 1091 O O . ASN A 1 155 ? 48.153 44.863 22.067 1.00 24.49 ? 155 ASN A O 1 ATOM 1092 C CB . ASN A 1 155 ? 50.577 45.904 23.367 1.00 25.48 ? 155 ASN A CB 1 ATOM 1093 C CG . ASN A 1 155 ? 49.743 47.138 23.789 1.00 25.82 ? 155 ASN A CG 1 ATOM 1094 O OD1 . ASN A 1 155 ? 49.017 47.708 22.989 1.00 27.55 ? 155 ASN A OD1 1 ATOM 1095 N ND2 . ASN A 1 155 ? 49.858 47.550 25.060 1.00 25.48 ? 155 ASN A ND2 1 ATOM 1096 N N . GLY A 1 156 ? 48.648 46.246 20.378 1.00 19.13 ? 156 GLY A N 1 ATOM 1097 C CA . GLY A 1 156 ? 47.289 46.216 19.858 1.00 19.77 ? 156 GLY A CA 1 ATOM 1098 C C . GLY A 1 156 ? 46.247 47.133 20.459 1.00 19.59 ? 156 GLY A C 1 ATOM 1099 O O . GLY A 1 156 ? 45.090 47.051 20.072 1.00 19.78 ? 156 GLY A O 1 ATOM 1100 N N . GLN A 1 157 ? 46.626 48.032 21.363 1.00 14.51 ? 157 GLN A N 1 ATOM 1101 C CA . GLN A 1 157 ? 45.619 48.888 21.955 1.00 15.42 ? 157 GLN A CA 1 ATOM 1102 C C . GLN A 1 157 ? 45.222 50.017 20.999 1.00 14.21 ? 157 GLN A C 1 ATOM 1103 O O . GLN A 1 157 ? 44.054 50.361 20.912 1.00 14.72 ? 157 GLN A O 1 ATOM 1104 C CB . GLN A 1 157 ? 46.135 49.496 23.241 1.00 15.78 ? 157 GLN A CB 1 ATOM 1105 C CG . GLN A 1 157 ? 46.035 48.579 24.442 1.00 16.41 ? 157 GLN A CG 1 ATOM 1106 C CD . GLN A 1 157 ? 46.385 49.353 25.705 1.00 16.35 ? 157 GLN A CD 1 ATOM 1107 O OE1 . GLN A 1 157 ? 45.561 50.068 26.287 1.00 19.53 ? 157 GLN A OE1 1 ATOM 1108 N NE2 . GLN A 1 157 ? 47.627 49.276 26.070 1.00 14.68 ? 157 GLN A NE2 1 ATOM 1109 N N . LEU A 1 158 ? 46.214 50.610 20.335 1.00 15.70 ? 158 LEU A N 1 ATOM 1110 C CA . LEU A 1 158 ? 45.944 51.660 19.357 1.00 14.89 ? 158 LEU A CA 1 ATOM 1111 C C . LEU A 1 158 ? 46.165 50.959 18.019 1.00 15.47 ? 158 LEU A C 1 ATOM 1112 O O A LEU A 1 158 ? 47.206 50.354 17.768 0.50 15.43 ? 158 LEU A O 1 ATOM 1113 O O B LEU A 1 158 ? 47.293 50.583 17.668 0.50 15.12 ? 158 LEU A O 1 ATOM 1114 C CB . LEU A 1 158 ? 46.905 52.839 19.555 1.00 17.21 ? 158 LEU A CB 1 ATOM 1115 C CG A LEU A 1 158 ? 46.695 54.091 18.696 0.50 20.37 ? 158 LEU A CG 1 ATOM 1116 C CG B LEU A 1 158 ? 46.990 53.819 18.421 0.50 15.31 ? 158 LEU A CG 1 ATOM 1117 C CD1 A LEU A 1 158 ? 47.852 55.064 18.986 0.50 22.26 ? 158 LEU A CD1 1 ATOM 1118 C CD1 B LEU A 1 158 ? 45.671 54.557 18.487 0.50 13.84 ? 158 LEU A CD1 1 ATOM 1119 C CD2 A LEU A 1 158 ? 46.689 53.746 17.222 0.50 22.84 ? 158 LEU A CD2 1 ATOM 1120 C CD2 B LEU A 1 158 ? 48.192 54.779 18.541 0.50 16.41 ? 158 LEU A CD2 1 ATOM 1121 N N . GLU A 1 159 ? 45.124 50.989 17.198 1.00 13.78 ? 159 GLU A N 1 ATOM 1122 C CA . GLU A 1 159 ? 45.198 50.342 15.888 1.00 14.43 ? 159 GLU A CA 1 ATOM 1123 C C . GLU A 1 159 ? 44.855 51.283 14.765 1.00 12.85 ? 159 GLU A C 1 ATOM 1124 O O . GLU A 1 159 ? 43.835 51.965 14.782 1.00 12.97 ? 159 GLU A O 1 ATOM 1125 C CB . GLU A 1 159 ? 44.230 49.156 15.877 1.00 14.31 ? 159 GLU A CB 1 ATOM 1126 C CG . GLU A 1 159 ? 44.140 48.448 14.547 1.00 15.80 ? 159 GLU A CG 1 ATOM 1127 C CD . GLU A 1 159 ? 43.166 47.293 14.604 1.00 17.16 ? 159 GLU A CD 1 ATOM 1128 O OE1 . GLU A 1 159 ? 43.477 46.285 15.315 1.00 16.93 ? 159 GLU A OE1 1 ATOM 1129 O OE2 . GLU A 1 159 ? 42.099 47.397 13.958 1.00 14.97 ? 159 GLU A OE2 1 ATOM 1130 N N . PHE A 1 160 ? 45.719 51.281 13.762 1.00 12.92 ? 160 PHE A N 1 ATOM 1131 C CA . PHE A 1 160 ? 45.460 52.110 12.603 1.00 12.04 ? 160 PHE A CA 1 ATOM 1132 C C . PHE A 1 160 ? 44.524 51.387 11.649 1.00 12.98 ? 160 PHE A C 1 ATOM 1133 O O . PHE A 1 160 ? 44.680 50.190 11.354 1.00 13.78 ? 160 PHE A O 1 ATOM 1134 C CB . PHE A 1 160 ? 46.803 52.426 11.933 1.00 13.01 ? 160 PHE A CB 1 ATOM 1135 C CG . PHE A 1 160 ? 47.693 53.260 12.800 1.00 11.49 ? 160 PHE A CG 1 ATOM 1136 C CD1 . PHE A 1 160 ? 47.400 54.608 12.994 1.00 13.38 ? 160 PHE A CD1 1 ATOM 1137 C CD2 . PHE A 1 160 ? 48.770 52.681 13.484 1.00 14.08 ? 160 PHE A CD2 1 ATOM 1138 C CE1 . PHE A 1 160 ? 48.176 55.400 13.872 1.00 13.72 ? 160 PHE A CE1 1 ATOM 1139 C CE2 . PHE A 1 160 ? 49.538 53.467 14.346 1.00 14.26 ? 160 PHE A CE2 1 ATOM 1140 C CZ . PHE A 1 160 ? 49.238 54.804 14.534 1.00 14.62 ? 160 PHE A CZ 1 ATOM 1141 N N . VAL A 1 161 ? 43.552 52.146 11.176 1.00 10.80 ? 161 VAL A N 1 ATOM 1142 C CA . VAL A 1 161 ? 42.564 51.651 10.210 1.00 12.27 ? 161 VAL A CA 1 ATOM 1143 C C . VAL A 1 161 ? 42.765 52.445 8.928 1.00 11.49 ? 161 VAL A C 1 ATOM 1144 O O . VAL A 1 161 ? 42.894 53.684 8.944 1.00 13.16 ? 161 VAL A O 1 ATOM 1145 C CB . VAL A 1 161 ? 41.124 51.741 10.775 1.00 11.63 ? 161 VAL A CB 1 ATOM 1146 C CG1 . VAL A 1 161 ? 41.026 50.726 11.951 1.00 13.52 ? 161 VAL A CG1 1 ATOM 1147 C CG2 . VAL A 1 161 ? 40.802 53.123 11.279 1.00 13.46 ? 161 VAL A CG2 1 ATOM 1148 N N . THR A 1 162 ? 42.830 51.674 7.828 1.00 11.44 ? 162 THR A N 1 ATOM 1149 C CA . THR A 1 162 ? 43.136 52.151 6.447 1.00 12.16 ? 162 THR A CA 1 ATOM 1150 C C . THR A 1 162 ? 44.601 52.602 6.390 1.00 13.00 ? 162 THR A C 1 ATOM 1151 O O . THR A 1 162 ? 45.437 52.020 5.695 1.00 14.16 ? 162 THR A O 1 ATOM 1152 C CB . THR A 1 162 ? 42.267 53.295 5.977 1.00 11.90 ? 162 THR A CB 1 ATOM 1153 O OG1 . THR A 1 162 ? 40.900 52.905 6.037 1.00 14.34 ? 162 THR A OG1 1 ATOM 1154 C CG2 . THR A 1 162 ? 42.603 53.556 4.475 1.00 13.90 ? 162 THR A CG2 1 ATOM 1155 N N . GLY A 1 163 ? 44.929 53.640 7.145 1.00 12.05 ? 163 GLY A N 1 ATOM 1156 C CA . GLY A 1 163 ? 46.303 54.130 7.164 1.00 12.71 ? 163 GLY A CA 1 ATOM 1157 C C . GLY A 1 163 ? 46.670 55.071 6.049 1.00 12.37 ? 163 GLY A C 1 ATOM 1158 O O . GLY A 1 163 ? 47.838 55.251 5.727 1.00 12.68 ? 163 GLY A O 1 ATOM 1159 N N . GLY A 1 164 ? 45.650 55.648 5.410 1.00 11.44 ? 164 GLY A N 1 ATOM 1160 C CA . GLY A 1 164 ? 45.957 56.636 4.382 1.00 12.38 ? 164 GLY A CA 1 ATOM 1161 C C . GLY A 1 164 ? 46.248 57.976 5.026 1.00 12.18 ? 164 GLY A C 1 ATOM 1162 O O . GLY A 1 164 ? 45.954 58.228 6.203 1.00 11.72 ? 164 GLY A O 1 ATOM 1163 N N . TRP A 1 165 ? 46.854 58.870 4.263 1.00 10.10 ? 165 TRP A N 1 ATOM 1164 C CA . TRP A 1 165 ? 47.112 60.223 4.732 1.00 9.68 ? 165 TRP A CA 1 ATOM 1165 C C . TRP A 1 165 ? 45.790 60.845 5.209 1.00 11.46 ? 165 TRP A C 1 ATOM 1166 O O . TRP A 1 165 ? 45.772 61.584 6.186 1.00 11.30 ? 165 TRP A O 1 ATOM 1167 C CB . TRP A 1 165 ? 47.710 61.042 3.570 1.00 11.42 ? 165 TRP A CB 1 ATOM 1168 C CG . TRP A 1 165 ? 48.552 62.188 4.048 1.00 11.69 ? 165 TRP A CG 1 ATOM 1169 C CD1 . TRP A 1 165 ? 48.382 63.515 3.737 1.00 13.39 ? 165 TRP A CD1 1 ATOM 1170 C CD2 . TRP A 1 165 ? 49.733 62.113 4.852 1.00 12.92 ? 165 TRP A CD2 1 ATOM 1171 N NE1 . TRP A 1 165 ? 49.403 64.271 4.288 1.00 14.27 ? 165 TRP A NE1 1 ATOM 1172 C CE2 . TRP A 1 165 ? 50.235 63.433 4.982 1.00 12.50 ? 165 TRP A CE2 1 ATOM 1173 C CE3 . TRP A 1 165 ? 50.416 61.057 5.461 1.00 14.17 ? 165 TRP A CE3 1 ATOM 1174 C CZ2 . TRP A 1 165 ? 51.421 63.724 5.737 1.00 16.24 ? 165 TRP A CZ2 1 ATOM 1175 C CZ3 . TRP A 1 165 ? 51.594 61.344 6.204 1.00 17.43 ? 165 TRP A CZ3 1 ATOM 1176 C CH2 . TRP A 1 165 ? 52.067 62.659 6.324 1.00 17.44 ? 165 TRP A CH2 1 ATOM 1177 N N . VAL A 1 166 ? 44.702 60.571 4.484 1.00 9.90 ? 166 VAL A N 1 ATOM 1178 C CA . VAL A 1 166 ? 43.360 61.063 4.815 1.00 11.35 ? 166 VAL A CA 1 ATOM 1179 C C . VAL A 1 166 ? 42.347 59.907 4.625 1.00 11.16 ? 166 VAL A C 1 ATOM 1180 O O . VAL A 1 166 ? 42.738 58.758 4.351 1.00 12.02 ? 166 VAL A O 1 ATOM 1181 C CB . VAL A 1 166 ? 42.926 62.230 3.870 1.00 11.00 ? 166 VAL A CB 1 ATOM 1182 C CG1 . VAL A 1 166 ? 43.946 63.344 3.960 1.00 12.52 ? 166 VAL A CG1 1 ATOM 1183 C CG2 . VAL A 1 166 ? 42.806 61.731 2.409 1.00 13.46 ? 166 VAL A CG2 1 ATOM 1184 N N . MET A 1 167 ? 41.067 60.222 4.863 1.00 11.19 ? 167 MET A N 1 ATOM 1185 C CA . MET A 1 167 ? 39.943 59.289 4.531 1.00 11.16 ? 167 MET A CA 1 ATOM 1186 C C . MET A 1 167 ? 39.393 60.031 3.293 1.00 11.22 ? 167 MET A C 1 ATOM 1187 O O . MET A 1 167 ? 38.616 60.967 3.387 1.00 12.65 ? 167 MET A O 1 ATOM 1188 C CB . MET A 1 167 ? 38.954 59.290 5.696 1.00 12.71 ? 167 MET A CB 1 ATOM 1189 C CG . MET A 1 167 ? 37.673 58.530 5.371 1.00 11.77 ? 167 MET A CG 1 ATOM 1190 S SD . MET A 1 167 ? 36.506 58.593 6.767 1.00 13.19 ? 167 MET A SD 1 ATOM 1191 C CE . MET A 1 167 ? 37.517 57.864 8.081 1.00 12.75 ? 167 MET A CE 1 ATOM 1192 N N . PRO A 1 168 ? 39.783 59.580 2.109 1.00 10.74 ? 168 PRO A N 1 ATOM 1193 C CA . PRO A 1 168 ? 39.370 60.318 0.929 1.00 10.72 ? 168 PRO A CA 1 ATOM 1194 C C . PRO A 1 168 ? 37.980 60.329 0.460 1.00 9.94 ? 168 PRO A C 1 ATOM 1195 O O . PRO A 1 168 ? 37.222 59.406 0.711 1.00 11.39 ? 168 PRO A O 1 ATOM 1196 C CB . PRO A 1 168 ? 40.303 59.735 -0.164 1.00 11.31 ? 168 PRO A CB 1 ATOM 1197 C CG . PRO A 1 168 ? 40.384 58.312 0.192 1.00 11.87 ? 168 PRO A CG 1 ATOM 1198 C CD . PRO A 1 168 ? 40.615 58.413 1.746 1.00 11.11 ? 168 PRO A CD 1 ATOM 1199 N N . ASP A 1 169 ? 37.655 61.424 -0.231 1.00 10.59 ? 169 ASP A N 1 ATOM 1200 C CA . ASP A 1 169 ? 36.421 61.444 -0.987 1.00 10.59 ? 169 ASP A CA 1 ATOM 1201 C C . ASP A 1 169 ? 36.544 60.272 -1.974 1.00 11.27 ? 169 ASP A C 1 ATOM 1202 O O . ASP A 1 169 ? 37.644 59.939 -2.442 1.00 10.36 ? 169 ASP A O 1 ATOM 1203 C CB . ASP A 1 169 ? 36.379 62.755 -1.771 1.00 9.86 ? 169 ASP A CB 1 ATOM 1204 C CG . ASP A 1 169 ? 35.219 62.797 -2.764 1.00 10.86 ? 169 ASP A CG 1 ATOM 1205 O OD1 . ASP A 1 169 ? 34.132 62.277 -2.453 1.00 12.52 ? 169 ASP A OD1 1 ATOM 1206 O OD2 . ASP A 1 169 ? 35.389 63.385 -3.844 1.00 13.32 ? 169 ASP A OD2 1 ATOM 1207 N N . GLU A 1 170 ? 35.414 59.651 -2.302 1.00 9.90 ? 170 GLU A N 1 ATOM 1208 C CA . GLU A 1 170 ? 35.371 58.527 -3.258 1.00 10.61 ? 170 GLU A CA 1 ATOM 1209 C C . GLU A 1 170 ? 34.660 58.922 -4.546 1.00 10.03 ? 170 GLU A C 1 ATOM 1210 O O . GLU A 1 170 ? 34.680 58.134 -5.489 1.00 11.96 ? 170 GLU A O 1 ATOM 1211 C CB . GLU A 1 170 ? 34.703 57.321 -2.564 1.00 11.31 ? 170 GLU A CB 1 ATOM 1212 C CG . GLU A 1 170 ? 35.528 56.903 -1.319 1.00 11.44 ? 170 GLU A CG 1 ATOM 1213 C CD . GLU A 1 170 ? 34.959 55.666 -0.616 1.00 12.88 ? 170 GLU A CD 1 ATOM 1214 O OE1 . GLU A 1 170 ? 34.189 54.911 -1.264 1.00 12.22 ? 170 GLU A OE1 1 ATOM 1215 O OE2 . GLU A 1 170 ? 35.346 55.454 0.562 1.00 14.60 ? 170 GLU A OE2 1 ATOM 1216 N N . ALA A 1 171 ? 34.072 60.108 -4.628 1.00 10.14 ? 171 ALA A N 1 ATOM 1217 C CA . ALA A 1 171 ? 33.346 60.529 -5.855 1.00 9.25 ? 171 ALA A CA 1 ATOM 1218 C C . ALA A 1 171 ? 34.197 61.258 -6.864 1.00 10.17 ? 171 ALA A C 1 ATOM 1219 O O . ALA A 1 171 ? 34.182 60.916 -8.026 1.00 11.29 ? 171 ALA A O 1 ATOM 1220 C CB . ALA A 1 171 ? 32.170 61.415 -5.478 1.00 11.01 ? 171 ALA A CB 1 ATOM 1221 N N . ASN A 1 172 ? 34.914 62.279 -6.391 1.00 10.41 ? 172 ASN A N 1 ATOM 1222 C CA . ASN A 1 172 ? 35.673 63.159 -7.293 1.00 10.04 ? 172 ASN A CA 1 ATOM 1223 C C . ASN A 1 172 ? 37.124 62.786 -7.432 1.00 11.15 ? 172 ASN A C 1 ATOM 1224 O O . ASN A 1 172 ? 37.797 63.205 -8.372 1.00 12.28 ? 172 ASN A O 1 ATOM 1225 C CB . ASN A 1 172 ? 35.630 64.579 -6.719 1.00 10.17 ? 172 ASN A CB 1 ATOM 1226 C CG . ASN A 1 172 ? 34.234 65.145 -6.598 1.00 13.72 ? 172 ASN A CG 1 ATOM 1227 O OD1 . ASN A 1 172 ? 33.569 65.358 -7.587 1.00 15.18 ? 172 ASN A OD1 1 ATOM 1228 N ND2 . ASN A 1 172 ? 33.800 65.421 -5.373 1.00 13.10 ? 172 ASN A ND2 1 ATOM 1229 N N . SER A 1 173 ? 37.622 62.008 -6.492 1.00 9.47 ? 173 SER A N 1 ATOM 1230 C CA . SER A 1 173 ? 39.032 61.647 -6.499 1.00 8.49 ? 173 SER A CA 1 ATOM 1231 C C . SER A 1 173 ? 39.411 60.759 -7.653 1.00 9.14 ? 173 SER A C 1 ATOM 1232 O O A SER A 1 173 ? 38.628 59.941 -8.123 0.50 10.51 ? 173 SER A O 1 ATOM 1233 O O B SER A 1 173 ? 38.782 59.717 -7.929 0.50 12.50 ? 173 SER A O 1 ATOM 1234 C CB . SER A 1 173 ? 39.391 60.970 -5.182 1.00 6.97 ? 173 SER A CB 1 ATOM 1235 O OG A SER A 1 173 ? 38.520 59.867 -4.957 0.50 5.29 ? 173 SER A OG 1 ATOM 1236 O OG B SER A 1 173 ? 40.712 60.585 -5.068 0.50 26.25 ? 173 SER A OG 1 ATOM 1237 N N . HIS A 1 174 ? 40.617 60.971 -8.158 1.00 9.57 ? 174 HIS A N 1 ATOM 1238 C CA . HIS A 1 174 ? 41.131 60.105 -9.216 1.00 8.52 ? 174 HIS A CA 1 ATOM 1239 C C . HIS A 1 174 ? 41.770 58.922 -8.517 1.00 8.87 ? 174 HIS A C 1 ATOM 1240 O O . HIS A 1 174 ? 42.453 59.101 -7.486 1.00 9.22 ? 174 HIS A O 1 ATOM 1241 C CB . HIS A 1 174 ? 42.162 60.827 -10.044 1.00 10.26 ? 174 HIS A CB 1 ATOM 1242 C CG . HIS A 1 174 ? 42.422 60.158 -11.346 1.00 11.17 ? 174 HIS A CG 1 ATOM 1243 N ND1 . HIS A 1 174 ? 43.147 58.989 -11.444 1.00 11.47 ? 174 HIS A ND1 1 ATOM 1244 C CD2 . HIS A 1 174 ? 41.975 60.454 -12.589 1.00 11.51 ? 174 HIS A CD2 1 ATOM 1245 C CE1 . HIS A 1 174 ? 43.127 58.587 -12.705 1.00 12.30 ? 174 HIS A CE1 1 ATOM 1246 N NE2 . HIS A 1 174 ? 42.423 59.459 -13.407 1.00 12.17 ? 174 HIS A NE2 1 ATOM 1247 N N . TRP A 1 175 ? 41.611 57.726 -9.077 1.00 8.91 ? 175 TRP A N 1 ATOM 1248 C CA . TRP A 1 175 ? 42.224 56.559 -8.428 1.00 9.41 ? 175 TRP A CA 1 ATOM 1249 C C . TRP A 1 175 ? 43.719 56.718 -8.191 1.00 10.89 ? 175 TRP A C 1 ATOM 1250 O O . TRP A 1 175 ? 44.247 56.201 -7.210 1.00 10.58 ? 175 TRP A O 1 ATOM 1251 C CB . TRP A 1 175 ? 41.940 55.287 -9.223 1.00 9.67 ? 175 TRP A CB 1 ATOM 1252 C CG . TRP A 1 175 ? 42.780 55.093 -10.475 1.00 9.38 ? 175 TRP A CG 1 ATOM 1253 C CD1 . TRP A 1 175 ? 42.423 55.453 -11.769 1.00 11.12 ? 175 TRP A CD1 1 ATOM 1254 C CD2 . TRP A 1 175 ? 44.065 54.469 -10.561 1.00 10.47 ? 175 TRP A CD2 1 ATOM 1255 N NE1 . TRP A 1 175 ? 43.459 55.068 -12.623 1.00 11.03 ? 175 TRP A NE1 1 ATOM 1256 C CE2 . TRP A 1 175 ? 44.460 54.466 -11.903 1.00 11.50 ? 175 TRP A CE2 1 ATOM 1257 C CE3 . TRP A 1 175 ? 44.924 53.894 -9.611 1.00 11.46 ? 175 TRP A CE3 1 ATOM 1258 C CZ2 . TRP A 1 175 ? 45.678 53.917 -12.327 1.00 11.51 ? 175 TRP A CZ2 1 ATOM 1259 C CZ3 . TRP A 1 175 ? 46.123 53.338 -10.039 1.00 12.92 ? 175 TRP A CZ3 1 ATOM 1260 C CH2 . TRP A 1 175 ? 46.495 53.356 -11.387 1.00 12.89 ? 175 TRP A CH2 1 ATOM 1261 N N . ARG A 1 176 ? 44.429 57.406 -9.098 1.00 10.78 ? 176 ARG A N 1 ATOM 1262 C CA . ARG A 1 176 ? 45.860 57.594 -8.901 1.00 10.81 ? 176 ARG A CA 1 ATOM 1263 C C . ARG A 1 176 ? 46.130 58.350 -7.625 1.00 10.15 ? 176 ARG A C 1 ATOM 1264 O O . ARG A 1 176 ? 47.122 58.052 -6.946 1.00 10.56 ? 176 ARG A O 1 ATOM 1265 C CB . ARG A 1 176 ? 46.464 58.354 -10.127 1.00 12.53 ? 176 ARG A CB 1 ATOM 1266 C CG . ARG A 1 176 ? 46.413 57.469 -11.379 1.00 12.47 ? 176 ARG A CG 1 ATOM 1267 C CD . ARG A 1 176 ? 46.372 58.307 -12.670 1.00 15.25 ? 176 ARG A CD 1 ATOM 1268 N NE . ARG A 1 176 ? 47.491 59.209 -12.751 1.00 15.00 ? 176 ARG A NE 1 ATOM 1269 C CZ . ARG A 1 176 ? 47.637 60.044 -13.773 1.00 15.41 ? 176 ARG A CZ 1 ATOM 1270 N NH1 . ARG A 1 176 ? 46.729 60.036 -14.758 1.00 14.78 ? 176 ARG A NH1 1 ATOM 1271 N NH2 . ARG A 1 176 ? 48.613 60.934 -13.752 1.00 16.50 ? 176 ARG A NH2 1 ATOM 1272 N N . ASN A 1 177 ? 45.290 59.327 -7.277 1.00 9.77 ? 177 ASN A N 1 ATOM 1273 C CA . ASN A 1 177 ? 45.519 60.100 -6.045 1.00 9.58 ? 177 ASN A CA 1 ATOM 1274 C C . ASN A 1 177 ? 44.980 59.362 -4.829 1.00 9.87 ? 177 ASN A C 1 ATOM 1275 O O . ASN A 1 177 ? 45.511 59.576 -3.721 1.00 10.78 ? 177 ASN A O 1 ATOM 1276 C CB . ASN A 1 177 ? 44.885 61.488 -6.136 1.00 10.34 ? 177 ASN A CB 1 ATOM 1277 C CG . ASN A 1 177 ? 45.571 62.350 -7.163 1.00 12.38 ? 177 ASN A CG 1 ATOM 1278 O OD1 . ASN A 1 177 ? 46.724 62.134 -7.491 1.00 11.47 ? 177 ASN A OD1 1 ATOM 1279 N ND2 . ASN A 1 177 ? 44.838 63.335 -7.702 1.00 13.93 ? 177 ASN A ND2 1 ATOM 1280 N N . VAL A 1 178 ? 44.000 58.496 -5.003 1.00 10.29 ? 178 VAL A N 1 ATOM 1281 C CA . VAL A 1 178 ? 43.564 57.680 -3.877 1.00 9.57 ? 178 VAL A CA 1 ATOM 1282 C C . VAL A 1 178 ? 44.767 56.791 -3.530 1.00 10.50 ? 178 VAL A C 1 ATOM 1283 O O . VAL A 1 178 ? 45.113 56.623 -2.357 1.00 11.03 ? 178 VAL A O 1 ATOM 1284 C CB . VAL A 1 178 ? 42.362 56.793 -4.255 1.00 9.57 ? 178 VAL A CB 1 ATOM 1285 C CG1 . VAL A 1 178 ? 42.056 55.808 -3.137 1.00 12.16 ? 178 VAL A CG1 1 ATOM 1286 C CG2 . VAL A 1 178 ? 41.115 57.673 -4.481 1.00 13.14 ? 178 VAL A CG2 1 ATOM 1287 N N . LEU A 1 179 ? 45.444 56.213 -4.537 1.00 10.79 ? 179 LEU A N 1 ATOM 1288 C CA . LEU A 1 179 ? 46.603 55.377 -4.257 1.00 10.26 ? 179 LEU A CA 1 ATOM 1289 C C . LEU A 1 179 ? 47.742 56.207 -3.684 1.00 10.90 ? 179 LEU A C 1 ATOM 1290 O O . LEU A 1 179 ? 48.421 55.748 -2.747 1.00 10.85 ? 179 LEU A O 1 ATOM 1291 C CB . LEU A 1 179 ? 47.097 54.689 -5.560 1.00 11.33 ? 179 LEU A CB 1 ATOM 1292 C CG . LEU A 1 179 ? 48.408 53.855 -5.399 1.00 11.40 ? 179 LEU A CG 1 ATOM 1293 C CD1 . LEU A 1 179 ? 48.235 52.714 -4.383 1.00 12.68 ? 179 LEU A CD1 1 ATOM 1294 C CD2 . LEU A 1 179 ? 48.785 53.234 -6.763 1.00 12.96 ? 179 LEU A CD2 1 ATOM 1295 N N . LEU A 1 180 ? 47.941 57.428 -4.173 1.00 10.28 ? 180 LEU A N 1 ATOM 1296 C CA . LEU A 1 180 ? 49.042 58.268 -3.708 1.00 9.90 ? 180 LEU A CA 1 ATOM 1297 C C . LEU A 1 180 ? 48.861 58.502 -2.208 1.00 9.90 ? 180 LEU A C 1 ATOM 1298 O O . LEU A 1 180 ? 49.851 58.318 -1.434 1.00 10.44 ? 180 LEU A O 1 ATOM 1299 C CB . LEU A 1 180 ? 48.994 59.620 -4.456 1.00 11.24 ? 180 LEU A CB 1 ATOM 1300 C CG . LEU A 1 180 ? 50.121 60.588 -4.093 1.00 12.41 ? 180 LEU A CG 1 ATOM 1301 C CD1 . LEU A 1 180 ? 51.415 60.038 -4.685 1.00 14.22 ? 180 LEU A CD1 1 ATOM 1302 C CD2 . LEU A 1 180 ? 49.844 61.967 -4.644 1.00 13.27 ? 180 LEU A CD2 1 ATOM 1303 N N . GLN A 1 181 ? 47.660 58.908 -1.781 1.00 10.20 ? 181 GLN A N 1 ATOM 1304 C CA . GLN A 1 181 ? 47.480 59.221 -0.348 1.00 9.71 ? 181 GLN A CA 1 ATOM 1305 C C . GLN A 1 181 ? 47.525 57.980 0.529 1.00 11.26 ? 181 GLN A C 1 ATOM 1306 O O . GLN A 1 181 ? 48.078 58.042 1.628 1.00 10.70 ? 181 GLN A O 1 ATOM 1307 C CB . GLN A 1 181 ? 46.204 60.051 -0.143 1.00 9.83 ? 181 GLN A CB 1 ATOM 1308 C CG . GLN A 1 181 ? 44.894 59.340 -0.368 1.00 10.67 ? 181 GLN A CG 1 ATOM 1309 C CD . GLN A 1 181 ? 44.520 58.388 0.759 1.00 13.59 ? 181 GLN A CD 1 ATOM 1310 O OE1 . GLN A 1 181 ? 44.748 58.693 1.930 1.00 13.21 ? 181 GLN A OE1 1 ATOM 1311 N NE2 . GLN A 1 181 ? 43.903 57.255 0.406 1.00 12.29 ? 181 GLN A NE2 1 ATOM 1312 N N . LEU A 1 182 ? 47.042 56.850 0.025 1.00 10.12 ? 182 LEU A N 1 ATOM 1313 C CA . LEU A 1 182 ? 47.128 55.598 0.774 1.00 9.43 ? 182 LEU A CA 1 ATOM 1314 C C . LEU A 1 182 ? 48.595 55.245 0.948 1.00 11.52 ? 182 LEU A C 1 ATOM 1315 O O . LEU A 1 182 ? 49.028 54.848 2.029 1.00 11.53 ? 182 LEU A O 1 ATOM 1316 C CB . LEU A 1 182 ? 46.389 54.469 0.025 1.00 9.82 ? 182 LEU A CB 1 ATOM 1317 C CG . LEU A 1 182 ? 46.492 53.081 0.660 1.00 9.23 ? 182 LEU A CG 1 ATOM 1318 C CD1 . LEU A 1 182 ? 45.762 53.083 2.049 1.00 13.04 ? 182 LEU A CD1 1 ATOM 1319 C CD2 . LEU A 1 182 ? 45.832 52.040 -0.275 1.00 11.64 ? 182 LEU A CD2 1 ATOM 1320 N N . THR A 1 183 ? 49.391 55.363 -0.101 1.00 10.82 ? 183 THR A N 1 ATOM 1321 C CA . THR A 1 183 ? 50.797 55.025 -0.041 1.00 11.74 ? 183 THR A CA 1 ATOM 1322 C C . THR A 1 183 ? 51.528 55.994 0.889 1.00 11.31 ? 183 THR A C 1 ATOM 1323 O O . THR A 1 183 ? 52.428 55.567 1.645 1.00 11.57 ? 183 THR A O 1 ATOM 1324 C CB . THR A 1 183 ? 51.419 55.096 -1.466 1.00 11.98 ? 183 THR A CB 1 ATOM 1325 O OG1 . THR A 1 183 ? 50.727 54.207 -2.331 1.00 11.51 ? 183 THR A OG1 1 ATOM 1326 C CG2 . THR A 1 183 ? 52.869 54.703 -1.403 1.00 13.44 ? 183 THR A CG2 1 ATOM 1327 N N . GLU A 1 184 ? 51.164 57.271 0.890 1.00 10.40 ? 184 GLU A N 1 ATOM 1328 C CA . GLU A 1 184 ? 51.868 58.224 1.745 1.00 10.57 ? 184 GLU A CA 1 ATOM 1329 C C . GLU A 1 184 ? 51.652 57.858 3.209 1.00 10.31 ? 184 GLU A C 1 ATOM 1330 O O . GLU A 1 184 ? 52.621 57.849 3.989 1.00 13.40 ? 184 GLU A O 1 ATOM 1331 C CB . GLU A 1 184 ? 51.313 59.630 1.472 1.00 12.86 ? 184 GLU A CB 1 ATOM 1332 C CG . GLU A 1 184 ? 52.162 60.793 1.977 1.00 15.36 ? 184 GLU A CG 1 ATOM 1333 C CD . GLU A 1 184 ? 53.571 60.844 1.335 1.00 14.53 ? 184 GLU A CD 1 ATOM 1334 O OE1 . GLU A 1 184 ? 53.761 60.442 0.177 1.00 15.87 ? 184 GLU A OE1 1 ATOM 1335 O OE2 . GLU A 1 184 ? 54.485 61.303 2.011 1.00 17.33 ? 184 GLU A OE2 1 ATOM 1336 N N . GLY A 1 185 ? 50.415 57.542 3.562 1.00 11.44 ? 185 GLY A N 1 ATOM 1337 C CA . GLY A 1 185 ? 50.141 57.186 4.951 1.00 11.51 ? 185 GLY A CA 1 ATOM 1338 C C . GLY A 1 185 ? 50.733 55.844 5.322 1.00 12.50 ? 185 GLY A C 1 ATOM 1339 O O . GLY A 1 185 ? 51.363 55.716 6.407 1.00 12.29 ? 185 GLY A O 1 ATOM 1340 N N . GLN A 1 186 ? 50.604 54.846 4.466 1.00 10.70 ? 186 GLN A N 1 ATOM 1341 C CA . GLN A 1 186 ? 51.125 53.525 4.838 1.00 11.19 ? 186 GLN A CA 1 ATOM 1342 C C . GLN A 1 186 ? 52.647 53.475 4.819 1.00 12.50 ? 186 GLN A C 1 ATOM 1343 O O . GLN A 1 186 ? 53.254 52.703 5.601 1.00 11.39 ? 186 GLN A O 1 ATOM 1344 C CB . GLN A 1 186 ? 50.518 52.427 3.942 1.00 10.86 ? 186 GLN A CB 1 ATOM 1345 C CG . GLN A 1 186 ? 49.002 52.268 4.154 1.00 13.34 ? 186 GLN A CG 1 ATOM 1346 C CD . GLN A 1 186 ? 48.578 50.879 3.944 1.00 13.29 ? 186 GLN A CD 1 ATOM 1347 O OE1 . GLN A 1 186 ? 49.190 50.170 3.158 1.00 17.44 ? 186 GLN A OE1 1 ATOM 1348 N NE2 . GLN A 1 186 ? 47.542 50.444 4.636 1.00 14.52 ? 186 GLN A NE2 1 ATOM 1349 N N . THR A 1 187 ? 53.321 54.260 3.981 1.00 12.86 ? 187 THR A N 1 ATOM 1350 C CA . THR A 1 187 ? 54.771 54.215 3.965 1.00 12.32 ? 187 THR A CA 1 ATOM 1351 C C . THR A 1 187 ? 55.249 54.815 5.272 1.00 13.60 ? 187 THR A C 1 ATOM 1352 O O . THR A 1 187 ? 56.198 54.297 5.885 1.00 13.27 ? 187 THR A O 1 ATOM 1353 C CB . THR A 1 187 ? 55.282 54.981 2.740 1.00 11.91 ? 187 THR A CB 1 ATOM 1354 O OG1 . THR A 1 187 ? 54.756 54.323 1.562 1.00 12.92 ? 187 THR A OG1 1 ATOM 1355 C CG2 . THR A 1 187 ? 56.845 54.977 2.692 1.00 13.35 ? 187 THR A CG2 1 ATOM 1356 N N . TRP A 1 188 ? 54.579 55.868 5.724 1.00 12.94 ? 188 TRP A N 1 ATOM 1357 C CA . TRP A 1 188 ? 54.935 56.502 7.003 1.00 12.83 ? 188 TRP A CA 1 ATOM 1358 C C . TRP A 1 188 ? 54.707 55.477 8.129 1.00 13.44 ? 188 TRP A C 1 ATOM 1359 O O . TRP A 1 188 ? 55.600 55.250 8.987 1.00 13.26 ? 188 TRP A O 1 ATOM 1360 C CB . TRP A 1 188 ? 54.042 57.720 7.239 1.00 14.24 ? 188 TRP A CB 1 ATOM 1361 C CG . TRP A 1 188 ? 54.498 58.518 8.447 1.00 14.97 ? 188 TRP A CG 1 ATOM 1362 C CD1 . TRP A 1 188 ? 55.381 59.536 8.437 1.00 15.43 ? 188 TRP A CD1 1 ATOM 1363 C CD2 . TRP A 1 188 ? 54.170 58.256 9.826 1.00 13.94 ? 188 TRP A CD2 1 ATOM 1364 N NE1 . TRP A 1 188 ? 55.672 59.936 9.739 1.00 15.13 ? 188 TRP A NE1 1 ATOM 1365 C CE2 . TRP A 1 188 ? 54.931 59.162 10.604 1.00 14.16 ? 188 TRP A CE2 1 ATOM 1366 C CE3 . TRP A 1 188 ? 53.330 57.342 10.462 1.00 14.24 ? 188 TRP A CE3 1 ATOM 1367 C CZ2 . TRP A 1 188 ? 54.876 59.170 12.010 1.00 15.11 ? 188 TRP A CZ2 1 ATOM 1368 C CZ3 . TRP A 1 188 ? 53.277 57.340 11.883 1.00 15.57 ? 188 TRP A CZ3 1 ATOM 1369 C CH2 . TRP A 1 188 ? 54.047 58.253 12.620 1.00 15.05 ? 188 TRP A CH2 1 ATOM 1370 N N . LEU A 1 189 ? 53.574 54.792 8.104 1.00 12.19 ? 189 LEU A N 1 ATOM 1371 C CA . LEU A 1 189 ? 53.285 53.805 9.170 1.00 13.11 ? 189 LEU A CA 1 ATOM 1372 C C . LEU A 1 189 ? 54.283 52.661 9.174 1.00 15.50 ? 189 LEU A C 1 ATOM 1373 O O . LEU A 1 189 ? 54.676 52.176 10.252 1.00 15.68 ? 189 LEU A O 1 ATOM 1374 C CB . LEU A 1 189 ? 51.870 53.212 9.034 1.00 12.49 ? 189 LEU A CB 1 ATOM 1375 C CG . LEU A 1 189 ? 50.710 54.079 9.464 1.00 11.14 ? 189 LEU A CG 1 ATOM 1376 C CD1 . LEU A 1 189 ? 49.390 53.391 9.122 1.00 12.92 ? 189 LEU A CD1 1 ATOM 1377 C CD2 . LEU A 1 189 ? 50.766 54.292 11.013 1.00 12.94 ? 189 LEU A CD2 1 ATOM 1378 N N . LYS A 1 190 ? 54.718 52.180 8.019 1.00 12.65 ? 190 LYS A N 1 ATOM 1379 C CA . LYS A 1 190 ? 55.662 51.077 8.036 1.00 14.52 ? 190 LYS A CA 1 ATOM 1380 C C . LYS A 1 190 ? 56.999 51.545 8.621 1.00 14.40 ? 190 LYS A C 1 ATOM 1381 O O . LYS A 1 190 ? 57.611 50.822 9.427 1.00 15.66 ? 190 LYS A O 1 ATOM 1382 C CB . LYS A 1 190 ? 55.894 50.495 6.626 1.00 16.28 ? 190 LYS A CB 1 ATOM 1383 C CG . LYS A 1 190 ? 56.796 49.259 6.641 1.00 19.42 ? 190 LYS A CG 1 ATOM 1384 C CD . LYS A 1 190 ? 57.069 48.754 5.265 1.00 26.47 ? 190 LYS A CD 1 ATOM 1385 C CE . LYS A 1 190 ? 57.778 47.412 5.310 1.00 30.27 ? 190 LYS A CE 1 ATOM 1386 N NZ . LYS A 1 190 ? 58.050 46.964 3.899 1.00 31.52 ? 190 LYS A NZ 1 ATOM 1387 N N . GLN A 1 191 ? 57.443 52.720 8.208 1.00 14.80 ? 191 GLN A N 1 ATOM 1388 C CA . GLN A 1 191 ? 58.714 53.256 8.658 1.00 19.13 ? 191 GLN A CA 1 ATOM 1389 C C . GLN A 1 191 ? 58.735 53.543 10.142 1.00 18.34 ? 191 GLN A C 1 ATOM 1390 O O . GLN A 1 191 ? 59.684 53.142 10.850 1.00 21.90 ? 191 GLN A O 1 ATOM 1391 C CB . GLN A 1 191 ? 59.054 54.546 7.903 1.00 19.90 ? 191 GLN A CB 1 ATOM 1392 C CG . GLN A 1 191 ? 60.429 55.098 8.341 1.00 26.81 ? 191 GLN A CG 1 ATOM 1393 C CD . GLN A 1 191 ? 60.938 56.260 7.482 1.00 31.17 ? 191 GLN A CD 1 ATOM 1394 O OE1 . GLN A 1 191 ? 62.017 56.797 7.755 1.00 36.06 ? 191 GLN A OE1 1 ATOM 1395 N NE2 . GLN A 1 191 ? 60.174 56.652 6.461 1.00 32.88 ? 191 GLN A NE2 1 ATOM 1396 N N . PHE A 1 192 ? 57.712 54.208 10.645 1.00 16.56 ? 192 PHE A N 1 ATOM 1397 C CA . PHE A 1 192 ? 57.727 54.600 12.037 1.00 17.00 ? 192 PHE A CA 1 ATOM 1398 C C . PHE A 1 192 ? 56.979 53.783 13.072 1.00 18.23 ? 192 PHE A C 1 ATOM 1399 O O . PHE A 1 192 ? 57.359 53.802 14.248 1.00 21.84 ? 192 PHE A O 1 ATOM 1400 C CB . PHE A 1 192 ? 57.296 56.054 12.148 1.00 16.25 ? 192 PHE A CB 1 ATOM 1401 C CG . PHE A 1 192 ? 58.200 56.995 11.401 1.00 16.45 ? 192 PHE A CG 1 ATOM 1402 C CD1 . PHE A 1 192 ? 59.436 57.378 11.957 1.00 19.48 ? 192 PHE A CD1 1 ATOM 1403 C CD2 . PHE A 1 192 ? 57.852 57.456 10.127 1.00 16.74 ? 192 PHE A CD2 1 ATOM 1404 C CE1 . PHE A 1 192 ? 60.318 58.217 11.247 1.00 19.91 ? 192 PHE A CE1 1 ATOM 1405 C CE2 . PHE A 1 192 ? 58.711 58.288 9.406 1.00 16.84 ? 192 PHE A CE2 1 ATOM 1406 C CZ . PHE A 1 192 ? 59.967 58.681 9.971 1.00 18.39 ? 192 PHE A CZ 1 ATOM 1407 N N . MET A 1 193 ? 55.937 53.068 12.666 1.00 16.46 ? 193 MET A N 1 ATOM 1408 C CA . MET A 1 193 ? 55.143 52.250 13.599 1.00 16.11 ? 193 MET A CA 1 ATOM 1409 C C . MET A 1 193 ? 55.295 50.766 13.304 1.00 16.36 ? 193 MET A C 1 ATOM 1410 O O . MET A 1 193 ? 54.761 49.919 14.040 1.00 17.41 ? 193 MET A O 1 ATOM 1411 C CB . MET A 1 193 ? 53.644 52.611 13.504 1.00 15.74 ? 193 MET A CB 1 ATOM 1412 C CG A MET A 1 193 ? 53.259 53.974 14.094 0.50 14.17 ? 193 MET A CG 1 ATOM 1413 C CG B MET A 1 193 ? 53.519 54.237 13.691 0.50 18.64 ? 193 MET A CG 1 ATOM 1414 S SD A MET A 1 193 ? 53.459 53.990 15.924 0.50 16.53 ? 193 MET A SD 1 ATOM 1415 S SD B MET A 1 193 ? 54.453 55.045 14.984 0.50 24.32 ? 193 MET A SD 1 ATOM 1416 C CE A MET A 1 193 ? 54.854 55.098 16.120 0.50 20.25 ? 193 MET A CE 1 ATOM 1417 C CE B MET A 1 193 ? 53.650 54.176 16.288 0.50 23.07 ? 193 MET A CE 1 ATOM 1418 N N . ASN A 1 194 ? 55.982 50.436 12.212 1.00 16.01 ? 194 ASN A N 1 ATOM 1419 C CA . ASN A 1 194 ? 56.151 49.046 11.807 1.00 17.70 ? 194 ASN A CA 1 ATOM 1420 C C . ASN A 1 194 ? 54.846 48.256 11.692 1.00 16.90 ? 194 ASN A C 1 ATOM 1421 O O . ASN A 1 194 ? 54.737 47.106 12.152 1.00 18.40 ? 194 ASN A O 1 ATOM 1422 C CB . ASN A 1 194 ? 57.078 48.338 12.807 1.00 19.96 ? 194 ASN A CB 1 ATOM 1423 C CG . ASN A 1 194 ? 57.585 47.021 12.286 1.00 26.62 ? 194 ASN A CG 1 ATOM 1424 O OD1 . ASN A 1 194 ? 57.737 46.839 11.085 1.00 25.51 ? 194 ASN A OD1 1 ATOM 1425 N ND2 . ASN A 1 194 ? 57.868 46.108 13.205 1.00 31.70 ? 194 ASN A ND2 1 ATOM 1426 N N . VAL A 1 195 ? 53.828 48.883 11.091 1.00 15.84 ? 195 VAL A N 1 ATOM 1427 C CA . VAL A 1 195 ? 52.565 48.210 10.883 1.00 16.11 ? 195 VAL A CA 1 ATOM 1428 C C . VAL A 1 195 ? 51.983 48.669 9.555 1.00 14.86 ? 195 VAL A C 1 ATOM 1429 O O . VAL A 1 195 ? 52.250 49.786 9.120 1.00 15.26 ? 195 VAL A O 1 ATOM 1430 C CB . VAL A 1 195 ? 51.475 48.534 11.990 1.00 16.04 ? 195 VAL A CB 1 ATOM 1431 C CG1 . VAL A 1 195 ? 51.911 48.066 13.365 1.00 22.72 ? 195 VAL A CG1 1 ATOM 1432 C CG2 . VAL A 1 195 ? 51.152 49.999 12.027 1.00 16.63 ? 195 VAL A CG2 1 ATOM 1433 N N . THR A 1 196 ? 51.246 47.751 8.938 1.00 14.05 ? 196 THR A N 1 ATOM 1434 C CA . THR A 1 196 ? 50.496 47.998 7.690 1.00 14.44 ? 196 THR A CA 1 ATOM 1435 C C . THR A 1 196 ? 49.053 47.501 7.875 1.00 14.63 ? 196 THR A C 1 ATOM 1436 O O . THR A 1 196 ? 48.791 46.300 7.924 1.00 15.13 ? 196 THR A O 1 ATOM 1437 C CB . THR A 1 196 ? 51.131 47.256 6.498 1.00 15.71 ? 196 THR A CB 1 ATOM 1438 O OG1 . THR A 1 196 ? 52.498 47.686 6.353 1.00 17.18 ? 196 THR A OG1 1 ATOM 1439 C CG2 . THR A 1 196 ? 50.349 47.589 5.208 1.00 18.28 ? 196 THR A CG2 1 ATOM 1440 N N . PRO A 1 197 ? 48.086 48.423 7.995 1.00 14.09 ? 197 PRO A N 1 ATOM 1441 C CA . PRO A 1 197 ? 46.687 48.048 8.182 1.00 12.87 ? 197 PRO A CA 1 ATOM 1442 C C . PRO A 1 197 ? 46.177 47.171 7.062 1.00 12.66 ? 197 PRO A C 1 ATOM 1443 O O . PRO A 1 197 ? 46.530 47.416 5.874 1.00 13.81 ? 197 PRO A O 1 ATOM 1444 C CB . PRO A 1 197 ? 45.950 49.406 8.163 1.00 12.76 ? 197 PRO A CB 1 ATOM 1445 C CG . PRO A 1 197 ? 46.973 50.345 8.696 1.00 13.49 ? 197 PRO A CG 1 ATOM 1446 C CD . PRO A 1 197 ? 48.261 49.877 8.104 1.00 13.53 ? 197 PRO A CD 1 ATOM 1447 N N . THR A 1 198 ? 45.344 46.199 7.408 1.00 12.43 ? 198 THR A N 1 ATOM 1448 C CA . THR A 1 198 ? 44.708 45.357 6.396 1.00 13.98 ? 198 THR A CA 1 ATOM 1449 C C . THR A 1 198 ? 43.188 45.516 6.474 1.00 13.16 ? 198 THR A C 1 ATOM 1450 O O . THR A 1 198 ? 42.449 44.832 5.760 1.00 13.21 ? 198 THR A O 1 ATOM 1451 C CB . THR A 1 198 ? 45.037 43.876 6.554 1.00 15.46 ? 198 THR A CB 1 ATOM 1452 O OG1 . THR A 1 198 ? 44.588 43.449 7.839 1.00 16.23 ? 198 THR A OG1 1 ATOM 1453 C CG2 . THR A 1 198 ? 46.524 43.615 6.400 1.00 16.66 ? 198 THR A CG2 1 ATOM 1454 N N . ALA A 1 199 ? 42.704 46.402 7.349 1.00 12.60 ? 199 ALA A N 1 ATOM 1455 C CA . ALA A 1 199 ? 41.277 46.715 7.459 1.00 12.81 ? 199 ALA A CA 1 ATOM 1456 C C . ALA A 1 199 ? 41.086 48.211 7.225 1.00 12.66 ? 199 ALA A C 1 ATOM 1457 O O . ALA A 1 199 ? 41.826 49.012 7.776 1.00 11.70 ? 199 ALA A O 1 ATOM 1458 C CB . ALA A 1 199 ? 40.737 46.337 8.862 1.00 13.82 ? 199 ALA A CB 1 ATOM 1459 N N . SER A 1 200 ? 40.128 48.575 6.383 1.00 11.87 ? 200 SER A N 1 ATOM 1460 C CA . SER A 1 200 ? 39.846 49.963 6.066 1.00 12.58 ? 200 SER A CA 1 ATOM 1461 C C . SER A 1 200 ? 38.570 50.451 6.775 1.00 12.58 ? 200 SER A C 1 ATOM 1462 O O . SER A 1 200 ? 37.616 49.679 6.959 1.00 12.49 ? 200 SER A O 1 ATOM 1463 C CB . SER A 1 200 ? 39.710 50.097 4.548 1.00 11.84 ? 200 SER A CB 1 ATOM 1464 O OG . SER A 1 200 ? 39.463 51.446 4.190 1.00 15.36 ? 200 SER A OG 1 ATOM 1465 N N . TRP A 1 201 ? 38.576 51.731 7.146 1.00 12.25 ? 201 TRP A N 1 ATOM 1466 C CA . TRP A 1 201 ? 37.486 52.390 7.861 1.00 11.20 ? 201 TRP A CA 1 ATOM 1467 C C . TRP A 1 201 ? 37.141 53.686 7.120 1.00 12.83 ? 201 TRP A C 1 ATOM 1468 O O . TRP A 1 201 ? 37.955 54.606 7.085 1.00 12.74 ? 201 TRP A O 1 ATOM 1469 C CB . TRP A 1 201 ? 38.035 52.680 9.265 1.00 12.23 ? 201 TRP A CB 1 ATOM 1470 C CG . TRP A 1 201 ? 37.179 53.521 10.214 1.00 12.31 ? 201 TRP A CG 1 ATOM 1471 C CD1 . TRP A 1 201 ? 37.330 54.858 10.509 1.00 14.18 ? 201 TRP A CD1 1 ATOM 1472 C CD2 . TRP A 1 201 ? 36.207 53.029 11.134 1.00 12.68 ? 201 TRP A CD2 1 ATOM 1473 N NE1 . TRP A 1 201 ? 36.524 55.209 11.549 1.00 13.10 ? 201 TRP A NE1 1 ATOM 1474 C CE2 . TRP A 1 201 ? 35.829 54.109 11.963 1.00 11.23 ? 201 TRP A CE2 1 ATOM 1475 C CE3 . TRP A 1 201 ? 35.635 51.775 11.353 1.00 13.09 ? 201 TRP A CE3 1 ATOM 1476 C CZ2 . TRP A 1 201 ? 34.887 53.971 13.010 1.00 12.41 ? 201 TRP A CZ2 1 ATOM 1477 C CZ3 . TRP A 1 201 ? 34.696 51.620 12.400 1.00 13.60 ? 201 TRP A CZ3 1 ATOM 1478 C CH2 . TRP A 1 201 ? 34.340 52.723 13.210 1.00 14.30 ? 201 TRP A CH2 1 ATOM 1479 N N . ALA A 1 202 ? 35.970 53.726 6.501 1.00 11.24 ? 202 ALA A N 1 ATOM 1480 C CA . ALA A 1 202 ? 35.523 54.914 5.745 1.00 11.25 ? 202 ALA A CA 1 ATOM 1481 C C . ALA A 1 202 ? 34.096 55.272 6.167 1.00 11.67 ? 202 ALA A C 1 ATOM 1482 O O . ALA A 1 202 ? 33.080 54.872 5.572 1.00 12.26 ? 202 ALA A O 1 ATOM 1483 C CB . ALA A 1 202 ? 35.606 54.645 4.246 1.00 12.52 ? 202 ALA A CB 1 ATOM 1484 N N . ILE A 1 203 ? 34.046 55.978 7.276 1.00 11.51 ? 203 ILE A N 1 ATOM 1485 C CA . ILE A 1 203 ? 32.760 56.332 7.877 1.00 11.70 ? 203 ILE A CA 1 ATOM 1486 C C . ILE A 1 203 ? 32.093 57.609 7.402 1.00 12.50 ? 203 ILE A C 1 ATOM 1487 O O . ILE A 1 203 ? 30.914 57.816 7.638 1.00 13.52 ? 203 ILE A O 1 ATOM 1488 C CB . ILE A 1 203 ? 32.855 56.409 9.435 1.00 11.32 ? 203 ILE A CB 1 ATOM 1489 C CG1 . ILE A 1 203 ? 34.000 57.324 9.897 1.00 12.51 ? 203 ILE A CG1 1 ATOM 1490 C CG2 . ILE A 1 203 ? 33.106 54.934 9.975 1.00 13.53 ? 203 ILE A CG2 1 ATOM 1491 C CD1 . ILE A 1 203 ? 33.897 57.692 11.408 1.00 11.61 ? 203 ILE A CD1 1 ATOM 1492 N N . ASP A 1 204 ? 32.850 58.451 6.688 1.00 11.21 ? 204 ASP A N 1 ATOM 1493 C CA . ASP A 1 204 ? 32.277 59.729 6.282 1.00 11.98 ? 204 ASP A CA 1 ATOM 1494 C C . ASP A 1 204 ? 32.224 60.136 4.794 1.00 10.86 ? 204 ASP A C 1 ATOM 1495 O O . ASP A 1 204 ? 31.530 61.090 4.520 1.00 14.20 ? 204 ASP A O 1 ATOM 1496 C CB . ASP A 1 204 ? 32.967 60.850 7.086 1.00 12.03 ? 204 ASP A CB 1 ATOM 1497 C CG . ASP A 1 204 ? 32.062 62.073 7.297 1.00 12.98 ? 204 ASP A CG 1 ATOM 1498 O OD1 . ASP A 1 204 ? 30.811 62.005 7.418 1.00 13.50 ? 204 ASP A OD1 1 ATOM 1499 O OD2 . ASP A 1 204 ? 32.635 63.189 7.363 1.00 13.54 ? 204 ASP A OD2 1 ATOM 1500 N N . PRO A 1 205 ? 32.972 59.471 3.866 1.00 11.46 ? 205 PRO A N 1 ATOM 1501 C CA . PRO A 1 205 ? 32.819 59.943 2.462 1.00 12.50 ? 205 PRO A CA 1 ATOM 1502 C C . PRO A 1 205 ? 31.343 59.886 2.051 1.00 12.99 ? 205 PRO A C 1 ATOM 1503 O O . PRO A 1 205 ? 30.588 58.996 2.496 1.00 13.78 ? 205 PRO A O 1 ATOM 1504 C CB . PRO A 1 205 ? 33.687 58.994 1.673 1.00 12.84 ? 205 PRO A CB 1 ATOM 1505 C CG . PRO A 1 205 ? 34.786 58.567 2.686 1.00 15.85 ? 205 PRO A CG 1 ATOM 1506 C CD . PRO A 1 205 ? 33.974 58.395 3.970 1.00 14.74 ? 205 PRO A CD 1 ATOM 1507 N N . PHE A 1 206 ? 30.916 60.804 1.185 1.00 13.35 ? 206 PHE A N 1 ATOM 1508 C CA . PHE A 1 206 ? 29.459 60.943 0.909 1.00 12.59 ? 206 PHE A CA 1 ATOM 1509 C C . PHE A 1 206 ? 29.064 60.050 -0.258 1.00 12.70 ? 206 PHE A C 1 ATOM 1510 O O . PHE A 1 206 ? 28.836 60.494 -1.401 1.00 13.28 ? 206 PHE A O 1 ATOM 1511 C CB . PHE A 1 206 ? 29.140 62.444 0.644 1.00 12.15 ? 206 PHE A CB 1 ATOM 1512 C CG . PHE A 1 206 ? 29.995 63.404 1.462 1.00 11.61 ? 206 PHE A CG 1 ATOM 1513 C CD1 . PHE A 1 206 ? 30.211 63.180 2.825 1.00 12.29 ? 206 PHE A CD1 1 ATOM 1514 C CD2 . PHE A 1 206 ? 30.608 64.510 0.847 1.00 12.57 ? 206 PHE A CD2 1 ATOM 1515 C CE1 . PHE A 1 206 ? 31.023 64.038 3.571 1.00 15.72 ? 206 PHE A CE1 1 ATOM 1516 C CE2 . PHE A 1 206 ? 31.417 65.382 1.581 1.00 12.59 ? 206 PHE A CE2 1 ATOM 1517 C CZ . PHE A 1 206 ? 31.634 65.149 2.959 1.00 13.38 ? 206 PHE A CZ 1 ATOM 1518 N N . GLY A 1 207 ? 28.923 58.766 0.071 1.00 12.12 ? 207 GLY A N 1 ATOM 1519 C CA . GLY A 1 207 ? 28.720 57.756 -0.946 1.00 12.54 ? 207 GLY A CA 1 ATOM 1520 C C . GLY A 1 207 ? 30.040 57.017 -1.119 1.00 11.07 ? 207 GLY A C 1 ATOM 1521 O O . GLY A 1 207 ? 31.124 57.549 -0.815 1.00 11.58 ? 207 GLY A O 1 ATOM 1522 N N . HIS A 1 208 ? 29.972 55.819 -1.686 1.00 12.03 ? 208 HIS A N 1 ATOM 1523 C CA . HIS A 1 208 ? 31.173 54.950 -1.787 1.00 10.66 ? 208 HIS A CA 1 ATOM 1524 C C . HIS A 1 208 ? 31.352 54.343 -3.150 1.00 10.21 ? 208 HIS A C 1 ATOM 1525 O O . HIS A 1 208 ? 30.359 53.969 -3.847 1.00 11.25 ? 208 HIS A O 1 ATOM 1526 C CB . HIS A 1 208 ? 31.023 53.837 -0.734 1.00 10.54 ? 208 HIS A CB 1 ATOM 1527 C CG . HIS A 1 208 ? 31.109 54.345 0.687 1.00 10.17 ? 208 HIS A CG 1 ATOM 1528 N ND1 . HIS A 1 208 ? 32.318 54.644 1.292 1.00 13.90 ? 208 HIS A ND1 1 ATOM 1529 C CD2 . HIS A 1 208 ? 30.134 54.641 1.588 1.00 13.47 ? 208 HIS A CD2 1 ATOM 1530 C CE1 . HIS A 1 208 ? 32.070 55.071 2.524 1.00 13.93 ? 208 HIS A CE1 1 ATOM 1531 N NE2 . HIS A 1 208 ? 30.768 55.076 2.730 1.00 14.54 ? 208 HIS A NE2 1 ATOM 1532 N N . SER A 1 209 ? 32.621 54.184 -3.508 1.00 9.98 ? 209 SER A N 1 ATOM 1533 C CA . SER A 1 209 ? 33.036 53.691 -4.806 1.00 10.07 ? 209 SER A CA 1 ATOM 1534 C C . SER A 1 209 ? 33.760 52.383 -4.760 1.00 10.96 ? 209 SER A C 1 ATOM 1535 O O . SER A 1 209 ? 34.565 52.145 -3.857 1.00 10.70 ? 209 SER A O 1 ATOM 1536 C CB . SER A 1 209 ? 33.963 54.731 -5.400 1.00 11.63 ? 209 SER A CB 1 ATOM 1537 O OG . SER A 1 209 ? 34.499 54.241 -6.639 1.00 12.76 ? 209 SER A OG 1 ATOM 1538 N N . PRO A 1 210 ? 33.478 51.487 -5.741 1.00 10.81 ? 210 PRO A N 1 ATOM 1539 C CA . PRO A 1 210 ? 34.181 50.192 -5.787 1.00 11.46 ? 210 PRO A CA 1 ATOM 1540 C C . PRO A 1 210 ? 35.670 50.372 -6.136 1.00 10.86 ? 210 PRO A C 1 ATOM 1541 O O . PRO A 1 210 ? 36.438 49.421 -6.067 1.00 11.21 ? 210 PRO A O 1 ATOM 1542 C CB . PRO A 1 210 ? 33.437 49.417 -6.883 1.00 11.12 ? 210 PRO A CB 1 ATOM 1543 C CG . PRO A 1 210 ? 32.911 50.513 -7.767 1.00 11.98 ? 210 PRO A CG 1 ATOM 1544 C CD . PRO A 1 210 ? 32.478 51.594 -6.814 1.00 10.78 ? 210 PRO A CD 1 ATOM 1545 N N . THR A 1 211 ? 36.099 51.600 -6.494 1.00 11.49 ? 211 THR A N 1 ATOM 1546 C CA . THR A 1 211 ? 37.509 51.823 -6.716 1.00 11.82 ? 211 THR A CA 1 ATOM 1547 C C . THR A 1 211 ? 38.279 51.566 -5.415 1.00 11.67 ? 211 THR A C 1 ATOM 1548 O O . THR A 1 211 ? 39.455 51.183 -5.458 1.00 12.23 ? 211 THR A O 1 ATOM 1549 C CB . THR A 1 211 ? 37.740 53.256 -7.197 1.00 11.83 ? 211 THR A CB 1 ATOM 1550 O OG1 . THR A 1 211 ? 37.161 53.315 -8.525 1.00 12.99 ? 211 THR A OG1 1 ATOM 1551 C CG2 . THR A 1 211 ? 39.210 53.641 -7.191 1.00 13.79 ? 211 THR A CG2 1 ATOM 1552 N N . MET A 1 212 ? 37.617 51.828 -4.271 1.00 10.92 ? 212 MET A N 1 ATOM 1553 C CA . MET A 1 212 ? 38.279 51.555 -2.992 1.00 12.01 ? 212 MET A CA 1 ATOM 1554 C C . MET A 1 212 ? 38.654 50.080 -2.776 1.00 11.46 ? 212 MET A C 1 ATOM 1555 O O . MET A 1 212 ? 39.833 49.754 -2.579 1.00 11.92 ? 212 MET A O 1 ATOM 1556 C CB . MET A 1 212 ? 37.422 52.097 -1.852 1.00 11.43 ? 212 MET A CB 1 ATOM 1557 C CG . MET A 1 212 ? 37.224 53.602 -1.917 1.00 14.84 ? 212 MET A CG 1 ATOM 1558 S SD . MET A 1 212 ? 38.667 54.613 -2.249 1.00 17.54 ? 212 MET A SD 1 ATOM 1559 C CE . MET A 1 212 ? 39.487 54.527 -0.668 1.00 19.29 ? 212 MET A CE 1 ATOM 1560 N N . PRO A 1 213 ? 37.670 49.158 -2.814 1.00 11.46 ? 213 PRO A N 1 ATOM 1561 C CA . PRO A 1 213 ? 38.103 47.766 -2.639 1.00 11.26 ? 213 PRO A CA 1 ATOM 1562 C C . PRO A 1 213 ? 39.078 47.366 -3.755 1.00 12.16 ? 213 PRO A C 1 ATOM 1563 O O . PRO A 1 213 ? 39.953 46.533 -3.536 1.00 13.64 ? 213 PRO A O 1 ATOM 1564 C CB . PRO A 1 213 ? 36.798 46.943 -2.702 1.00 11.47 ? 213 PRO A CB 1 ATOM 1565 C CG . PRO A 1 213 ? 35.796 47.906 -3.379 1.00 10.64 ? 213 PRO A CG 1 ATOM 1566 C CD . PRO A 1 213 ? 36.201 49.270 -2.834 1.00 11.12 ? 213 PRO A CD 1 ATOM 1567 N N . TYR A 1 214 ? 38.934 47.934 -4.966 1.00 12.53 ? 214 TYR A N 1 ATOM 1568 C CA . TYR A 1 214 ? 39.895 47.560 -6.035 1.00 11.85 ? 214 TYR A CA 1 ATOM 1569 C C . TYR A 1 214 ? 41.345 47.834 -5.581 1.00 12.22 ? 214 TYR A C 1 ATOM 1570 O O . TYR A 1 214 ? 42.243 46.962 -5.687 1.00 13.16 ? 214 TYR A O 1 ATOM 1571 C CB . TYR A 1 214 ? 39.609 48.368 -7.297 1.00 11.54 ? 214 TYR A CB 1 ATOM 1572 C CG . TYR A 1 214 ? 40.566 48.120 -8.469 1.00 12.26 ? 214 TYR A CG 1 ATOM 1573 C CD1 . TYR A 1 214 ? 40.341 47.047 -9.340 1.00 17.81 ? 214 TYR A CD1 1 ATOM 1574 C CD2 . TYR A 1 214 ? 41.626 48.980 -8.708 1.00 11.90 ? 214 TYR A CD2 1 ATOM 1575 C CE1 . TYR A 1 214 ? 41.160 46.866 -10.448 1.00 19.28 ? 214 TYR A CE1 1 ATOM 1576 C CE2 . TYR A 1 214 ? 42.451 48.801 -9.797 1.00 13.63 ? 214 TYR A CE2 1 ATOM 1577 C CZ . TYR A 1 214 ? 42.192 47.752 -10.661 1.00 17.12 ? 214 TYR A CZ 1 ATOM 1578 O OH . TYR A 1 214 ? 42.927 47.634 -11.832 1.00 19.23 ? 214 TYR A OH 1 ATOM 1579 N N . ILE A 1 215 ? 41.595 49.079 -5.161 1.00 10.68 ? 215 ILE A N 1 ATOM 1580 C CA . ILE A 1 215 ? 42.921 49.478 -4.731 1.00 11.30 ? 215 ILE A CA 1 ATOM 1581 C C . ILE A 1 215 ? 43.335 48.771 -3.439 1.00 10.68 ? 215 ILE A C 1 ATOM 1582 O O . ILE A 1 215 ? 44.452 48.263 -3.331 1.00 12.40 ? 215 ILE A O 1 ATOM 1583 C CB . ILE A 1 215 ? 42.987 51.012 -4.512 1.00 11.63 ? 215 ILE A CB 1 ATOM 1584 C CG1 . ILE A 1 215 ? 42.814 51.730 -5.829 1.00 12.98 ? 215 ILE A CG1 1 ATOM 1585 C CG2 . ILE A 1 215 ? 44.323 51.407 -3.804 1.00 13.72 ? 215 ILE A CG2 1 ATOM 1586 C CD1 . ILE A 1 215 ? 42.728 53.224 -5.691 1.00 15.79 ? 215 ILE A CD1 1 ATOM 1587 N N . LEU A 1 216 ? 42.414 48.722 -2.473 1.00 11.41 ? 216 LEU A N 1 ATOM 1588 C CA . LEU A 1 216 ? 42.743 48.097 -1.169 1.00 11.35 ? 216 LEU A CA 1 ATOM 1589 C C . LEU A 1 216 ? 43.094 46.610 -1.312 1.00 11.26 ? 216 LEU A C 1 ATOM 1590 O O . LEU A 1 216 ? 44.108 46.159 -0.766 1.00 12.03 ? 216 LEU A O 1 ATOM 1591 C CB . LEU A 1 216 ? 41.566 48.256 -0.201 1.00 11.21 ? 216 LEU A CB 1 ATOM 1592 C CG . LEU A 1 216 ? 41.162 49.689 0.161 1.00 10.98 ? 216 LEU A CG 1 ATOM 1593 C CD1 . LEU A 1 216 ? 39.913 49.675 0.948 1.00 13.09 ? 216 LEU A CD1 1 ATOM 1594 C CD2 . LEU A 1 216 ? 42.303 50.344 0.974 1.00 13.60 ? 216 LEU A CD2 1 ATOM 1595 N N . GLN A 1 217 ? 42.318 45.881 -2.129 1.00 12.01 ? 217 GLN A N 1 ATOM 1596 C CA . GLN A 1 217 ? 42.580 44.455 -2.289 1.00 11.94 ? 217 GLN A CA 1 ATOM 1597 C C . GLN A 1 217 ? 43.939 44.209 -2.967 1.00 12.84 ? 217 GLN A C 1 ATOM 1598 O O . GLN A 1 217 ? 44.598 43.186 -2.710 1.00 16.27 ? 217 GLN A O 1 ATOM 1599 C CB . GLN A 1 217 ? 41.415 43.808 -3.049 1.00 15.63 ? 217 GLN A CB 1 ATOM 1600 C CG . GLN A 1 217 ? 41.402 42.263 -3.101 1.00 15.58 ? 217 GLN A CG 1 ATOM 1601 C CD . GLN A 1 217 ? 42.317 41.723 -4.157 1.00 19.57 ? 217 GLN A CD 1 ATOM 1602 O OE1 . GLN A 1 217 ? 42.476 42.341 -5.202 1.00 21.13 ? 217 GLN A OE1 1 ATOM 1603 N NE2 . GLN A 1 217 ? 42.912 40.551 -3.911 1.00 21.64 ? 217 GLN A NE2 1 ATOM 1604 N N . LYS A 1 218 ? 44.411 45.163 -3.777 1.00 12.69 ? 218 LYS A N 1 ATOM 1605 C CA . LYS A 1 218 ? 45.715 45.040 -4.434 1.00 11.65 ? 218 LYS A CA 1 ATOM 1606 C C . LYS A 1 218 ? 46.846 45.651 -3.569 1.00 12.76 ? 218 LYS A C 1 ATOM 1607 O O . LYS A 1 218 ? 47.992 45.749 -4.015 1.00 13.14 ? 218 LYS A O 1 ATOM 1608 C CB . LYS A 1 218 ? 45.650 45.751 -5.806 1.00 12.54 ? 218 LYS A CB 1 ATOM 1609 C CG . LYS A 1 218 ? 44.819 44.946 -6.805 1.00 13.81 ? 218 LYS A CG 1 ATOM 1610 C CD . LYS A 1 218 ? 44.519 45.804 -8.056 1.00 13.76 ? 218 LYS A CD 1 ATOM 1611 C CE . LYS A 1 218 ? 44.173 44.961 -9.242 1.00 16.91 ? 218 LYS A CE 1 ATOM 1612 N NZ . LYS A 1 218 ? 43.079 43.980 -9.082 1.00 17.58 ? 218 LYS A NZ 1 ATOM 1613 N N . SER A 1 219 ? 46.475 46.077 -2.363 1.00 12.09 ? 219 SER A N 1 ATOM 1614 C CA . SER A 1 219 ? 47.376 46.669 -1.396 1.00 12.09 ? 219 SER A CA 1 ATOM 1615 C C . SER A 1 219 ? 47.380 45.895 -0.090 1.00 12.27 ? 219 SER A C 1 ATOM 1616 O O . SER A 1 219 ? 47.714 46.462 0.948 1.00 12.96 ? 219 SER A O 1 ATOM 1617 C CB . SER A 1 219 ? 47.029 48.142 -1.145 1.00 11.76 ? 219 SER A CB 1 ATOM 1618 O OG . SER A 1 219 ? 47.066 48.871 -2.389 1.00 12.98 ? 219 SER A OG 1 ATOM 1619 N N . GLY A 1 220 ? 47.057 44.606 -0.163 1.00 13.39 ? 220 GLY A N 1 ATOM 1620 C CA . GLY A 1 220 ? 47.132 43.752 1.014 1.00 12.80 ? 220 GLY A CA 1 ATOM 1621 C C . GLY A 1 220 ? 45.929 43.709 1.944 1.00 12.84 ? 220 GLY A C 1 ATOM 1622 O O . GLY A 1 220 ? 45.952 42.956 2.911 1.00 14.50 ? 220 GLY A O 1 ATOM 1623 N N . PHE A 1 221 ? 44.888 44.493 1.676 1.00 13.17 ? 221 PHE A N 1 ATOM 1624 C CA . PHE A 1 221 ? 43.735 44.513 2.585 1.00 10.62 ? 221 PHE A CA 1 ATOM 1625 C C . PHE A 1 221 ? 42.916 43.254 2.512 1.00 11.70 ? 221 PHE A C 1 ATOM 1626 O O . PHE A 1 221 ? 42.846 42.603 1.474 1.00 13.77 ? 221 PHE A O 1 ATOM 1627 C CB . PHE A 1 221 ? 42.831 45.718 2.313 1.00 11.89 ? 221 PHE A CB 1 ATOM 1628 C CG . PHE A 1 221 ? 43.398 46.994 2.830 1.00 10.34 ? 221 PHE A CG 1 ATOM 1629 C CD1 . PHE A 1 221 ? 44.529 47.601 2.222 1.00 10.68 ? 221 PHE A CD1 1 ATOM 1630 C CD2 . PHE A 1 221 ? 42.833 47.620 3.952 1.00 11.18 ? 221 PHE A CD2 1 ATOM 1631 C CE1 . PHE A 1 221 ? 45.053 48.786 2.745 1.00 11.21 ? 221 PHE A CE1 1 ATOM 1632 C CE2 . PHE A 1 221 ? 43.344 48.786 4.457 1.00 11.48 ? 221 PHE A CE2 1 ATOM 1633 C CZ . PHE A 1 221 ? 44.474 49.408 3.862 1.00 11.43 ? 221 PHE A CZ 1 ATOM 1634 N N . LYS A 1 222 ? 42.241 42.986 3.622 1.00 12.87 ? 222 LYS A N 1 ATOM 1635 C CA . LYS A 1 222 ? 41.362 41.851 3.710 1.00 12.96 ? 222 LYS A CA 1 ATOM 1636 C C . LYS A 1 222 ? 39.946 42.240 4.098 1.00 13.25 ? 222 LYS A C 1 ATOM 1637 O O . LYS A 1 222 ? 39.020 41.446 3.891 1.00 13.88 ? 222 LYS A O 1 ATOM 1638 C CB . LYS A 1 222 ? 41.885 40.865 4.747 1.00 16.33 ? 222 LYS A CB 1 ATOM 1639 C CG . LYS A 1 222 ? 43.302 40.374 4.521 1.00 19.74 ? 222 LYS A CG 1 ATOM 1640 C CD . LYS A 1 222 ? 43.552 39.613 3.249 1.00 26.60 ? 222 LYS A CD 1 ATOM 1641 C CE . LYS A 1 222 ? 45.014 39.122 3.281 1.00 33.05 ? 222 LYS A CE 1 ATOM 1642 N NZ . LYS A 1 222 ? 45.350 38.228 2.146 1.00 37.84 ? 222 LYS A NZ 1 ATOM 1643 N N . ASN A 1 223 ? 39.760 43.455 4.594 1.00 11.74 ? 223 ASN A N 1 ATOM 1644 C CA . ASN A 1 223 ? 38.440 43.877 5.032 1.00 12.09 ? 223 ASN A CA 1 ATOM 1645 C C . ASN A 1 223 ? 38.274 45.373 4.913 1.00 11.93 ? 223 ASN A C 1 ATOM 1646 O O . ASN A 1 223 ? 39.252 46.104 4.991 1.00 12.02 ? 223 ASN A O 1 ATOM 1647 C CB . ASN A 1 223 ? 38.207 43.531 6.541 1.00 12.34 ? 223 ASN A CB 1 ATOM 1648 C CG . ASN A 1 223 ? 38.278 42.044 6.821 1.00 13.98 ? 223 ASN A CG 1 ATOM 1649 O OD1 . ASN A 1 223 ? 39.335 41.534 7.291 1.00 17.56 ? 223 ASN A OD1 1 ATOM 1650 N ND2 . ASN A 1 223 ? 37.213 41.334 6.503 1.00 11.41 ? 223 ASN A ND2 1 ATOM 1651 N N . MET A 1 224 ? 37.039 45.814 4.754 1.00 11.50 ? 224 MET A N 1 ATOM 1652 C CA . MET A 1 224 ? 36.764 47.254 4.719 1.00 11.20 ? 224 MET A CA 1 ATOM 1653 C C . MET A 1 224 ? 35.349 47.548 5.281 1.00 12.40 ? 224 MET A C 1 ATOM 1654 O O . MET A 1 224 ? 34.451 46.666 5.280 1.00 12.56 ? 224 MET A O 1 ATOM 1655 C CB . MET A 1 224 ? 36.897 47.841 3.288 1.00 14.47 ? 224 MET A CB 1 ATOM 1656 C CG . MET A 1 224 ? 35.826 47.328 2.317 1.00 14.12 ? 224 MET A CG 1 ATOM 1657 S SD . MET A 1 224 ? 36.029 48.095 0.676 1.00 13.96 ? 224 MET A SD 1 ATOM 1658 C CE . MET A 1 224 ? 35.573 49.710 1.046 1.00 17.13 ? 224 MET A CE 1 ATOM 1659 N N . LEU A 1 225 ? 35.165 48.778 5.740 1.00 12.47 ? 225 LEU A N 1 ATOM 1660 C CA . LEU A 1 225 ? 33.923 49.201 6.316 1.00 11.50 ? 225 LEU A CA 1 ATOM 1661 C C . LEU A 1 225 ? 33.501 50.513 5.677 1.00 13.29 ? 225 LEU A C 1 ATOM 1662 O O . LEU A 1 225 ? 34.336 51.405 5.487 1.00 11.62 ? 225 LEU A O 1 ATOM 1663 C CB . LEU A 1 225 ? 34.117 49.370 7.846 1.00 11.85 ? 225 LEU A CB 1 ATOM 1664 C CG . LEU A 1 225 ? 32.909 49.963 8.588 1.00 12.01 ? 225 LEU A CG 1 ATOM 1665 C CD1 . LEU A 1 225 ? 32.814 49.356 10.002 1.00 13.60 ? 225 LEU A CD1 1 ATOM 1666 C CD2 . LEU A 1 225 ? 32.975 51.492 8.650 1.00 12.91 ? 225 LEU A CD2 1 ATOM 1667 N N . ILE A 1 226 ? 32.214 50.625 5.403 1.00 11.92 ? 226 ILE A N 1 ATOM 1668 C CA . ILE A 1 226 ? 31.622 51.834 4.840 1.00 11.09 ? 226 ILE A CA 1 ATOM 1669 C C . ILE A 1 226 ? 30.382 52.228 5.610 1.00 11.80 ? 226 ILE A C 1 ATOM 1670 O O . ILE A 1 226 ? 29.807 51.391 6.341 1.00 12.73 ? 226 ILE A O 1 ATOM 1671 C CB . ILE A 1 226 ? 31.328 51.668 3.317 1.00 12.48 ? 226 ILE A CB 1 ATOM 1672 C CG1 . ILE A 1 226 ? 30.250 50.607 3.106 1.00 12.15 ? 226 ILE A CG1 1 ATOM 1673 C CG2 . ILE A 1 226 ? 32.596 51.295 2.580 1.00 13.53 ? 226 ILE A CG2 1 ATOM 1674 C CD1 . ILE A 1 226 ? 29.883 50.400 1.577 1.00 12.83 ? 226 ILE A CD1 1 ATOM 1675 N N . GLN A 1 227 ? 29.933 53.469 5.447 1.00 12.65 ? 227 GLN A N 1 ATOM 1676 C CA . GLN A 1 227 ? 28.791 53.970 6.197 1.00 11.56 ? 227 GLN A CA 1 ATOM 1677 C C . GLN A 1 227 ? 27.788 54.800 5.405 1.00 13.92 ? 227 GLN A C 1 ATOM 1678 O O . GLN A 1 227 ? 26.591 54.570 5.532 1.00 13.87 ? 227 GLN A O 1 ATOM 1679 C CB . GLN A 1 227 ? 29.322 54.804 7.390 1.00 13.43 ? 227 GLN A CB 1 ATOM 1680 C CG . GLN A 1 227 ? 28.341 55.867 7.980 1.00 14.53 ? 227 GLN A CG 1 ATOM 1681 C CD . GLN A 1 227 ? 27.010 55.337 8.494 1.00 14.71 ? 227 GLN A CD 1 ATOM 1682 O OE1 . GLN A 1 227 ? 26.870 54.168 8.844 1.00 16.87 ? 227 GLN A OE1 1 ATOM 1683 N NE2 . GLN A 1 227 ? 26.032 56.229 8.553 1.00 14.47 ? 227 GLN A NE2 1 ATOM 1684 N N . ARG A 1 228 ? 28.249 55.744 4.596 1.00 13.47 ? 228 ARG A N 1 ATOM 1685 C CA . ARG A 1 228 ? 27.266 56.608 3.958 1.00 11.93 ? 228 ARG A CA 1 ATOM 1686 C C . ARG A 1 228 ? 26.715 56.097 2.680 1.00 13.29 ? 228 ARG A C 1 ATOM 1687 O O . ARG A 1 228 ? 27.279 56.339 1.611 1.00 13.78 ? 228 ARG A O 1 ATOM 1688 C CB . ARG A 1 228 ? 27.833 58.031 3.748 1.00 12.17 ? 228 ARG A CB 1 ATOM 1689 C CG . ARG A 1 228 ? 28.072 58.800 5.042 1.00 11.90 ? 228 ARG A CG 1 ATOM 1690 C CD . ARG A 1 228 ? 28.336 60.289 4.688 1.00 12.49 ? 228 ARG A CD 1 ATOM 1691 N NE . ARG A 1 228 ? 28.633 61.156 5.853 1.00 12.43 ? 228 ARG A NE 1 ATOM 1692 C CZ . ARG A 1 228 ? 27.726 61.845 6.540 1.00 14.71 ? 228 ARG A CZ 1 ATOM 1693 N NH1 . ARG A 1 228 ? 26.446 61.745 6.222 1.00 15.03 ? 228 ARG A NH1 1 ATOM 1694 N NH2 . ARG A 1 228 ? 28.123 62.725 7.464 1.00 17.03 ? 228 ARG A NH2 1 ATOM 1695 N N . THR A 1 229 ? 25.669 55.289 2.819 1.00 11.78 ? 229 THR A N 1 ATOM 1696 C CA . THR A 1 229 ? 24.952 54.762 1.677 1.00 12.58 ? 229 THR A CA 1 ATOM 1697 C C . THR A 1 229 ? 23.490 55.174 1.868 1.00 12.66 ? 229 THR A C 1 ATOM 1698 O O . THR A 1 229 ? 22.998 55.430 2.983 1.00 14.00 ? 229 THR A O 1 ATOM 1699 C CB . THR A 1 229 ? 25.073 53.213 1.547 1.00 13.68 ? 229 THR A CB 1 ATOM 1700 O OG1 . THR A 1 229 ? 24.443 52.616 2.690 1.00 14.00 ? 229 THR A OG1 1 ATOM 1701 C CG2 . THR A 1 229 ? 26.538 52.782 1.461 1.00 14.56 ? 229 THR A CG2 1 ATOM 1702 N N . HIS A 1 230 ? 22.789 55.242 0.730 1.00 12.59 ? 230 HIS A N 1 ATOM 1703 C CA . HIS A 1 230 ? 21.377 55.692 0.733 1.00 13.39 ? 230 HIS A CA 1 ATOM 1704 C C . HIS A 1 230 ? 20.558 54.938 1.802 1.00 12.31 ? 230 HIS A C 1 ATOM 1705 O O . HIS A 1 230 ? 20.660 53.730 1.923 1.00 13.27 ? 230 HIS A O 1 ATOM 1706 C CB . HIS A 1 230 ? 20.829 55.447 -0.671 1.00 12.86 ? 230 HIS A CB 1 ATOM 1707 C CG . HIS A 1 230 ? 19.544 56.146 -0.982 1.00 14.32 ? 230 HIS A CG 1 ATOM 1708 N ND1 . HIS A 1 230 ? 18.380 55.917 -0.285 1.00 13.75 ? 230 HIS A ND1 1 ATOM 1709 C CD2 . HIS A 1 230 ? 19.230 57.022 -1.966 1.00 14.50 ? 230 HIS A CD2 1 ATOM 1710 C CE1 . HIS A 1 230 ? 17.404 56.636 -0.809 1.00 14.99 ? 230 HIS A CE1 1 ATOM 1711 N NE2 . HIS A 1 230 ? 17.893 57.310 -1.839 1.00 14.53 ? 230 HIS A NE2 1 ATOM 1712 N N . TYR A 1 231 ? 19.748 55.693 2.551 1.00 13.75 ? 231 TYR A N 1 ATOM 1713 C CA . TYR A 1 231 ? 18.949 55.077 3.595 1.00 13.48 ? 231 TYR A CA 1 ATOM 1714 C C . TYR A 1 231 ? 18.075 53.953 3.038 1.00 15.07 ? 231 TYR A C 1 ATOM 1715 O O . TYR A 1 231 ? 17.810 52.977 3.756 1.00 15.73 ? 231 TYR A O 1 ATOM 1716 C CB . TYR A 1 231 ? 18.124 56.130 4.330 1.00 15.01 ? 231 TYR A CB 1 ATOM 1717 C CG . TYR A 1 231 ? 17.117 56.894 3.460 1.00 14.53 ? 231 TYR A CG 1 ATOM 1718 C CD1 . TYR A 1 231 ? 15.825 56.400 3.248 1.00 15.75 ? 231 TYR A CD1 1 ATOM 1719 C CD2 . TYR A 1 231 ? 17.479 58.110 2.853 1.00 14.43 ? 231 TYR A CD2 1 ATOM 1720 C CE1 . TYR A 1 231 ? 14.909 57.085 2.461 1.00 16.51 ? 231 TYR A CE1 1 ATOM 1721 C CE2 . TYR A 1 231 ? 16.587 58.807 2.057 1.00 15.85 ? 231 TYR A CE2 1 ATOM 1722 C CZ . TYR A 1 231 ? 15.291 58.292 1.866 1.00 15.34 ? 231 TYR A CZ 1 ATOM 1723 O OH . TYR A 1 231 ? 14.366 59.005 1.103 1.00 17.15 ? 231 TYR A OH 1 ATOM 1724 N N . SER A 1 232 ? 17.657 54.032 1.775 1.00 14.42 ? 232 SER A N 1 ATOM 1725 C CA . SER A 1 232 ? 16.824 52.949 1.233 1.00 15.30 ? 232 SER A CA 1 ATOM 1726 C C . SER A 1 232 ? 17.639 51.697 0.978 1.00 15.17 ? 232 SER A C 1 ATOM 1727 O O . SER A 1 232 ? 17.139 50.573 1.090 1.00 15.04 ? 232 SER A O 1 ATOM 1728 C CB . SER A 1 232 ? 16.157 53.366 -0.067 1.00 16.03 ? 232 SER A CB 1 ATOM 1729 O OG . SER A 1 232 ? 15.224 54.380 0.172 1.00 18.79 ? 232 SER A OG 1 ATOM 1730 N N . VAL A 1 233 ? 18.901 51.886 0.608 1.00 15.32 ? 233 VAL A N 1 ATOM 1731 C CA . VAL A 1 233 ? 19.795 50.757 0.410 1.00 15.03 ? 233 VAL A CA 1 ATOM 1732 C C . VAL A 1 233 ? 20.077 50.075 1.750 1.00 15.14 ? 233 VAL A C 1 ATOM 1733 O O . VAL A 1 233 ? 20.094 48.837 1.829 1.00 15.32 ? 233 VAL A O 1 ATOM 1734 C CB . VAL A 1 233 ? 21.122 51.236 -0.283 1.00 13.97 ? 233 VAL A CB 1 ATOM 1735 C CG1 . VAL A 1 233 ? 22.168 50.150 -0.254 1.00 13.97 ? 233 VAL A CG1 1 ATOM 1736 C CG2 . VAL A 1 233 ? 20.815 51.584 -1.743 1.00 15.39 ? 233 VAL A CG2 1 ATOM 1737 N N . LYS A 1 234 ? 20.373 50.862 2.784 1.00 14.05 ? 234 LYS A N 1 ATOM 1738 C CA . LYS A 1 234 ? 20.588 50.256 4.100 1.00 15.27 ? 234 LYS A CA 1 ATOM 1739 C C . LYS A 1 234 ? 19.361 49.418 4.495 1.00 15.11 ? 234 LYS A C 1 ATOM 1740 O O . LYS A 1 234 ? 19.536 48.300 4.988 1.00 14.85 ? 234 LYS A O 1 ATOM 1741 C CB . LYS A 1 234 ? 20.788 51.328 5.164 1.00 14.74 ? 234 LYS A CB 1 ATOM 1742 C CG . LYS A 1 234 ? 22.187 51.975 5.120 1.00 16.19 ? 234 LYS A CG 1 ATOM 1743 C CD . LYS A 1 234 ? 22.191 53.293 5.868 1.00 15.90 ? 234 LYS A CD 1 ATOM 1744 C CE . LYS A 1 234 ? 23.614 53.940 5.802 1.00 13.86 ? 234 LYS A CE 1 ATOM 1745 N NZ . LYS A 1 234 ? 24.497 53.377 6.895 1.00 12.79 ? 234 LYS A NZ 1 ATOM 1746 N N . LYS A 1 235 ? 18.144 49.950 4.305 1.00 14.70 ? 235 LYS A N 1 ATOM 1747 C CA . LYS A 1 235 ? 16.938 49.155 4.671 1.00 14.29 ? 235 LYS A CA 1 ATOM 1748 C C . LYS A 1 235 ? 16.826 47.874 3.871 1.00 15.35 ? 235 LYS A C 1 ATOM 1749 O O . LYS A 1 235 ? 16.591 46.785 4.429 1.00 16.38 ? 235 LYS A O 1 ATOM 1750 C CB . LYS A 1 235 ? 15.690 50.009 4.472 1.00 16.22 ? 235 LYS A CB 1 ATOM 1751 C CG . LYS A 1 235 ? 14.383 49.316 4.925 1.00 17.38 ? 235 LYS A CG 1 ATOM 1752 C CD . LYS A 1 235 ? 13.219 50.296 4.820 1.00 16.63 ? 235 LYS A CD 1 ATOM 1753 C CE . LYS A 1 235 ? 11.930 49.601 5.293 1.00 20.35 ? 235 LYS A CE 1 ATOM 1754 N NZ . LYS A 1 235 ? 10.749 50.525 5.253 1.00 30.18 ? 235 LYS A NZ 1 ATOM 1755 N N . GLU A 1 236 ? 17.009 47.960 2.568 1.00 15.27 ? 236 GLU A N 1 ATOM 1756 C CA . GLU A 1 236 ? 16.897 46.799 1.710 1.00 16.13 ? 236 GLU A CA 1 ATOM 1757 C C . GLU A 1 236 ? 17.921 45.720 2.041 1.00 17.67 ? 236 GLU A C 1 ATOM 1758 O O . GLU A 1 236 ? 17.613 44.526 2.133 1.00 17.69 ? 236 GLU A O 1 ATOM 1759 C CB . GLU A 1 236 ? 17.086 47.256 0.268 1.00 19.60 ? 236 GLU A CB 1 ATOM 1760 C CG . GLU A 1 236 ? 16.809 46.190 -0.782 1.00 25.65 ? 236 GLU A CG 1 ATOM 1761 C CD . GLU A 1 236 ? 15.311 45.875 -0.926 1.00 31.10 ? 236 GLU A CD 1 ATOM 1762 O OE1 . GLU A 1 236 ? 14.449 46.655 -0.443 1.00 33.61 ? 236 GLU A OE1 1 ATOM 1763 O OE2 . GLU A 1 236 ? 15.009 44.837 -1.535 1.00 34.42 ? 236 GLU A OE2 1 ATOM 1764 N N . LEU A 1 237 ? 19.171 46.129 2.203 1.00 15.02 ? 237 LEU A N 1 ATOM 1765 C CA . LEU A 1 237 ? 20.200 45.141 2.509 1.00 16.48 ? 237 LEU A CA 1 ATOM 1766 C C . LEU A 1 237 ? 20.039 44.604 3.928 1.00 15.62 ? 237 LEU A C 1 ATOM 1767 O O . LEU A 1 237 ? 20.272 43.399 4.156 1.00 18.13 ? 237 LEU A O 1 ATOM 1768 C CB . LEU A 1 237 ? 21.609 45.712 2.300 1.00 15.15 ? 237 LEU A CB 1 ATOM 1769 C CG . LEU A 1 237 ? 21.948 46.130 0.862 1.00 14.70 ? 237 LEU A CG 1 ATOM 1770 C CD1 . LEU A 1 237 ? 23.365 46.758 0.908 1.00 16.42 ? 237 LEU A CD1 1 ATOM 1771 C CD2 . LEU A 1 237 ? 21.850 44.971 -0.134 1.00 16.66 ? 237 LEU A CD2 1 ATOM 1772 N N . ALA A 1 238 ? 19.612 45.445 4.864 1.00 16.00 ? 238 ALA A N 1 ATOM 1773 C CA . ALA A 1 238 ? 19.395 44.970 6.226 1.00 15.48 ? 238 ALA A CA 1 ATOM 1774 C C . ALA A 1 238 ? 18.315 43.891 6.240 1.00 18.42 ? 238 ALA A C 1 ATOM 1775 O O . ALA A 1 238 ? 18.474 42.882 6.946 1.00 17.58 ? 238 ALA A O 1 ATOM 1776 C CB . ALA A 1 238 ? 18.989 46.119 7.132 1.00 16.02 ? 238 ALA A CB 1 ATOM 1777 N N . GLN A 1 239 ? 17.246 44.096 5.467 1.00 16.52 ? 239 GLN A N 1 ATOM 1778 C CA . GLN A 1 239 ? 16.159 43.110 5.466 1.00 18.69 ? 239 GLN A CA 1 ATOM 1779 C C . GLN A 1 239 ? 16.624 41.737 5.013 1.00 20.83 ? 239 GLN A C 1 ATOM 1780 O O . GLN A 1 239 ? 16.087 40.725 5.455 1.00 21.51 ? 239 GLN A O 1 ATOM 1781 C CB . GLN A 1 239 ? 15.027 43.600 4.593 1.00 17.57 ? 239 GLN A CB 1 ATOM 1782 C CG . GLN A 1 239 ? 14.283 44.752 5.257 1.00 22.65 ? 239 GLN A CG 1 ATOM 1783 C CD . GLN A 1 239 ? 13.160 45.344 4.411 1.00 26.98 ? 239 GLN A CD 1 ATOM 1784 O OE1 . GLN A 1 239 ? 13.250 45.444 3.175 1.00 31.47 ? 239 GLN A OE1 1 ATOM 1785 N NE2 . GLN A 1 239 ? 12.101 45.774 5.086 1.00 32.33 ? 239 GLN A NE2 1 ATOM 1786 N N . GLN A 1 240 ? 17.612 41.684 4.125 1.00 18.38 ? 240 GLN A N 1 ATOM 1787 C CA . GLN A 1 240 ? 18.140 40.421 3.621 1.00 19.23 ? 240 GLN A CA 1 ATOM 1788 C C . GLN A 1 240 ? 19.446 40.001 4.288 1.00 16.71 ? 240 GLN A C 1 ATOM 1789 O O . GLN A 1 240 ? 20.058 39.035 3.862 1.00 16.57 ? 240 GLN A O 1 ATOM 1790 C CB . GLN A 1 240 ? 18.413 40.521 2.118 1.00 20.23 ? 240 GLN A CB 1 ATOM 1791 C CG . GLN A 1 240 ? 17.253 41.091 1.309 1.00 23.99 ? 240 GLN A CG 1 ATOM 1792 C CD . GLN A 1 240 ? 16.013 40.242 1.458 1.00 25.67 ? 240 GLN A CD 1 ATOM 1793 O OE1 . GLN A 1 240 ? 14.881 40.760 1.540 1.00 32.75 ? 240 GLN A OE1 1 ATOM 1794 N NE2 . GLN A 1 240 ? 16.207 38.938 1.504 1.00 26.56 ? 240 GLN A NE2 1 ATOM 1795 N N . ARG A 1 241 ? 19.853 40.721 5.334 1.00 16.77 ? 241 ARG A N 1 ATOM 1796 C CA . ARG A 1 241 ? 21.132 40.476 5.995 1.00 15.12 ? 241 ARG A CA 1 ATOM 1797 C C . ARG A 1 241 ? 22.247 40.430 4.959 1.00 14.89 ? 241 ARG A C 1 ATOM 1798 O O . ARG A 1 241 ? 23.075 39.525 4.920 1.00 13.97 ? 241 ARG A O 1 ATOM 1799 C CB . ARG A 1 241 ? 21.123 39.189 6.834 1.00 15.58 ? 241 ARG A CB 1 ATOM 1800 C CG . ARG A 1 241 ? 20.109 39.288 7.974 1.00 17.07 ? 241 ARG A CG 1 ATOM 1801 C CD . ARG A 1 241 ? 20.194 38.142 8.966 1.00 19.50 ? 241 ARG A CD 1 ATOM 1802 N NE . ARG A 1 241 ? 20.185 36.841 8.337 1.00 27.50 ? 241 ARG A NE 1 ATOM 1803 C CZ . ARG A 1 241 ? 20.627 35.734 8.935 1.00 30.65 ? 241 ARG A CZ 1 ATOM 1804 N NH1 . ARG A 1 241 ? 21.102 35.796 10.180 1.00 31.70 ? 241 ARG A NH1 1 ATOM 1805 N NH2 . ARG A 1 241 ? 20.639 34.582 8.271 1.00 31.33 ? 241 ARG A NH2 1 ATOM 1806 N N . GLN A 1 242 ? 22.247 41.466 4.110 1.00 14.56 ? 242 GLN A N 1 ATOM 1807 C CA . GLN A 1 242 ? 23.274 41.594 3.061 1.00 13.75 ? 242 GLN A CA 1 ATOM 1808 C C . GLN A 1 242 ? 24.129 42.840 3.307 1.00 14.02 ? 242 GLN A C 1 ATOM 1809 O O . GLN A 1 242 ? 24.704 43.416 2.361 1.00 15.56 ? 242 GLN A O 1 ATOM 1810 C CB . GLN A 1 242 ? 22.601 41.648 1.679 1.00 14.91 ? 242 GLN A CB 1 ATOM 1811 C CG . GLN A 1 242 ? 21.974 40.305 1.280 1.00 15.51 ? 242 GLN A CG 1 ATOM 1812 C CD . GLN A 1 242 ? 21.151 40.425 0.024 1.00 15.74 ? 242 GLN A CD 1 ATOM 1813 O OE1 . GLN A 1 242 ? 20.606 41.486 -0.269 1.00 16.89 ? 242 GLN A OE1 1 ATOM 1814 N NE2 . GLN A 1 242 ? 21.080 39.337 -0.727 1.00 17.80 ? 242 GLN A NE2 1 ATOM 1815 N N . LEU A 1 243 ? 24.234 43.229 4.585 1.00 14.83 ? 243 LEU A N 1 ATOM 1816 C CA . LEU A 1 243 ? 25.060 44.385 4.942 1.00 13.46 ? 243 LEU A CA 1 ATOM 1817 C C . LEU A 1 243 ? 26.547 44.041 4.974 1.00 14.02 ? 243 LEU A C 1 ATOM 1818 O O . LEU A 1 243 ? 27.373 44.959 4.982 1.00 13.97 ? 243 LEU A O 1 ATOM 1819 C CB . LEU A 1 243 ? 24.614 44.962 6.283 1.00 12.22 ? 243 LEU A CB 1 ATOM 1820 C CG . LEU A 1 243 ? 23.250 45.673 6.267 1.00 15.00 ? 243 LEU A CG 1 ATOM 1821 C CD1 . LEU A 1 243 ? 22.813 45.849 7.723 1.00 18.18 ? 243 LEU A CD1 1 ATOM 1822 C CD2 . LEU A 1 243 ? 23.303 47.055 5.542 1.00 15.74 ? 243 LEU A CD2 1 ATOM 1823 N N . GLU A 1 244 ? 26.908 42.757 5.043 1.00 12.35 ? 244 GLU A N 1 ATOM 1824 C CA . GLU A 1 244 ? 28.281 42.322 4.929 1.00 12.89 ? 244 GLU A CA 1 ATOM 1825 C C . GLU A 1 244 ? 28.297 41.526 3.642 1.00 12.45 ? 244 GLU A C 1 ATOM 1826 O O . GLU A 1 244 ? 27.466 40.610 3.450 1.00 14.45 ? 244 GLU A O 1 ATOM 1827 C CB . GLU A 1 244 ? 28.717 41.480 6.132 1.00 12.60 ? 244 GLU A CB 1 ATOM 1828 C CG . GLU A 1 244 ? 29.001 42.406 7.320 1.00 13.03 ? 244 GLU A CG 1 ATOM 1829 C CD . GLU A 1 244 ? 29.342 41.705 8.607 1.00 13.37 ? 244 GLU A CD 1 ATOM 1830 O OE1 . GLU A 1 244 ? 28.766 40.645 8.898 1.00 15.72 ? 244 GLU A OE1 1 ATOM 1831 O OE2 . GLU A 1 244 ? 30.180 42.269 9.340 1.00 13.22 ? 244 GLU A OE2 1 ATOM 1832 N N . PHE A 1 245 ? 29.247 41.835 2.764 1.00 12.22 ? 245 PHE A N 1 ATOM 1833 C CA . PHE A 1 245 ? 29.297 41.188 1.467 1.00 12.62 ? 245 PHE A CA 1 ATOM 1834 C C . PHE A 1 245 ? 30.703 41.164 0.905 1.00 12.20 ? 245 PHE A C 1 ATOM 1835 O O . PHE A 1 245 ? 31.593 41.922 1.355 1.00 12.96 ? 245 PHE A O 1 ATOM 1836 C CB . PHE A 1 245 ? 28.346 41.936 0.487 1.00 12.90 ? 245 PHE A CB 1 ATOM 1837 C CG . PHE A 1 245 ? 28.490 43.423 0.528 1.00 12.71 ? 245 PHE A CG 1 ATOM 1838 C CD1 . PHE A 1 245 ? 29.431 44.063 -0.279 1.00 12.11 ? 245 PHE A CD1 1 ATOM 1839 C CD2 . PHE A 1 245 ? 27.687 44.199 1.383 1.00 13.18 ? 245 PHE A CD2 1 ATOM 1840 C CE1 . PHE A 1 245 ? 29.579 45.503 -0.255 1.00 13.49 ? 245 PHE A CE1 1 ATOM 1841 C CE2 . PHE A 1 245 ? 27.836 45.618 1.416 1.00 12.73 ? 245 PHE A CE2 1 ATOM 1842 C CZ . PHE A 1 245 ? 28.791 46.253 0.578 1.00 12.22 ? 245 PHE A CZ 1 ATOM 1843 N N . LEU A 1 246 ? 30.915 40.321 -0.098 1.00 13.06 ? 246 LEU A N 1 ATOM 1844 C CA . LEU A 1 246 ? 32.188 40.225 -0.813 1.00 11.83 ? 246 LEU A CA 1 ATOM 1845 C C . LEU A 1 246 ? 32.029 41.155 -1.998 1.00 12.43 ? 246 LEU A C 1 ATOM 1846 O O . LEU A 1 246 ? 31.364 40.836 -2.995 1.00 12.55 ? 246 LEU A O 1 ATOM 1847 C CB . LEU A 1 246 ? 32.432 38.761 -1.229 1.00 13.12 ? 246 LEU A CB 1 ATOM 1848 C CG . LEU A 1 246 ? 32.764 37.876 -0.004 1.00 16.63 ? 246 LEU A CG 1 ATOM 1849 C CD1 . LEU A 1 246 ? 32.733 36.387 -0.427 1.00 20.39 ? 246 LEU A CD1 1 ATOM 1850 C CD2 . LEU A 1 246 ? 34.155 38.213 0.481 1.00 21.34 ? 246 LEU A CD2 1 ATOM 1851 N N . TRP A 1 247 ? 32.649 42.315 -1.909 1.00 12.13 ? 247 TRP A N 1 ATOM 1852 C CA . TRP A 1 247 ? 32.480 43.347 -2.929 1.00 11.22 ? 247 TRP A CA 1 ATOM 1853 C C . TRP A 1 247 ? 33.509 43.153 -4.041 1.00 12.29 ? 247 TRP A C 1 ATOM 1854 O O . TRP A 1 247 ? 34.714 43.344 -3.831 1.00 12.19 ? 247 TRP A O 1 ATOM 1855 C CB . TRP A 1 247 ? 32.694 44.715 -2.272 1.00 11.75 ? 247 TRP A CB 1 ATOM 1856 C CG . TRP A 1 247 ? 32.209 45.902 -3.101 1.00 11.79 ? 247 TRP A CG 1 ATOM 1857 C CD1 . TRP A 1 247 ? 31.652 45.880 -4.352 1.00 10.90 ? 247 TRP A CD1 1 ATOM 1858 C CD2 . TRP A 1 247 ? 32.226 47.256 -2.690 1.00 11.33 ? 247 TRP A CD2 1 ATOM 1859 N NE1 . TRP A 1 247 ? 31.300 47.177 -4.732 1.00 11.30 ? 247 TRP A NE1 1 ATOM 1860 C CE2 . TRP A 1 247 ? 31.639 48.035 -3.721 1.00 10.66 ? 247 TRP A CE2 1 ATOM 1861 C CE3 . TRP A 1 247 ? 32.664 47.899 -1.536 1.00 12.18 ? 247 TRP A CE3 1 ATOM 1862 C CZ2 . TRP A 1 247 ? 31.489 49.424 -3.628 1.00 13.32 ? 247 TRP A CZ2 1 ATOM 1863 C CZ3 . TRP A 1 247 ? 32.515 49.284 -1.440 1.00 10.51 ? 247 TRP A CZ3 1 ATOM 1864 C CH2 . TRP A 1 247 ? 31.938 50.039 -2.470 1.00 11.43 ? 247 TRP A CH2 1 ATOM 1865 N N . ARG A 1 248 ? 33.017 42.744 -5.216 1.00 11.44 ? 248 ARG A N 1 ATOM 1866 C CA . ARG A 1 248 ? 33.909 42.576 -6.357 1.00 12.39 ? 248 ARG A CA 1 ATOM 1867 C C . ARG A 1 248 ? 33.613 43.628 -7.399 1.00 11.89 ? 248 ARG A C 1 ATOM 1868 O O . ARG A 1 248 ? 32.561 44.262 -7.355 1.00 11.67 ? 248 ARG A O 1 ATOM 1869 C CB . ARG A 1 248 ? 33.704 41.204 -7.037 1.00 13.53 ? 248 ARG A CB 1 ATOM 1870 C CG . ARG A 1 248 ? 32.299 41.039 -7.654 1.00 11.92 ? 248 ARG A CG 1 ATOM 1871 C CD . ARG A 1 248 ? 32.227 39.730 -8.487 1.00 15.35 ? 248 ARG A CD 1 ATOM 1872 N NE . ARG A 1 248 ? 32.273 38.568 -7.617 1.00 15.51 ? 248 ARG A NE 1 ATOM 1873 C CZ . ARG A 1 248 ? 32.220 37.311 -8.055 1.00 19.03 ? 248 ARG A CZ 1 ATOM 1874 N NH1 . ARG A 1 248 ? 32.142 37.071 -9.360 1.00 18.38 ? 248 ARG A NH1 1 ATOM 1875 N NH2 . ARG A 1 248 ? 32.213 36.302 -7.186 1.00 19.91 ? 248 ARG A NH2 1 ATOM 1876 N N . GLN A 1 249 ? 34.542 43.766 -8.353 1.00 12.01 ? 249 GLN A N 1 ATOM 1877 C CA . GLN A 1 249 ? 34.340 44.739 -9.432 1.00 12.03 ? 249 GLN A CA 1 ATOM 1878 C C . GLN A 1 249 ? 33.233 44.288 -10.378 1.00 13.36 ? 249 GLN A C 1 ATOM 1879 O O . GLN A 1 249 ? 32.933 43.107 -10.519 1.00 13.90 ? 249 GLN A O 1 ATOM 1880 C CB . GLN A 1 249 ? 35.671 44.931 -10.193 1.00 12.37 ? 249 GLN A CB 1 ATOM 1881 C CG . GLN A 1 249 ? 36.787 45.426 -9.250 1.00 13.00 ? 249 GLN A CG 1 ATOM 1882 C CD . GLN A 1 249 ? 36.385 46.719 -8.522 1.00 14.96 ? 249 GLN A CD 1 ATOM 1883 O OE1 . GLN A 1 249 ? 36.367 46.788 -7.235 1.00 15.57 ? 249 GLN A OE1 1 ATOM 1884 N NE2 . GLN A 1 249 ? 36.063 47.743 -9.282 1.00 10.80 ? 249 GLN A NE2 1 ATOM 1885 N N . ILE A 1 250 ? 32.602 45.266 -11.010 1.00 12.37 ? 250 ILE A N 1 ATOM 1886 C CA . ILE A 1 250 ? 31.468 44.954 -11.886 1.00 13.78 ? 250 ILE A CA 1 ATOM 1887 C C . ILE A 1 250 ? 31.746 44.032 -13.056 1.00 14.17 ? 250 ILE A C 1 ATOM 1888 O O . ILE A 1 250 ? 30.814 43.377 -13.530 1.00 15.45 ? 250 ILE A O 1 ATOM 1889 C CB . ILE A 1 250 ? 30.764 46.248 -12.403 1.00 14.40 ? 250 ILE A CB 1 ATOM 1890 C CG1 . ILE A 1 250 ? 31.748 47.151 -13.155 1.00 15.56 ? 250 ILE A CG1 1 ATOM 1891 C CG2 . ILE A 1 250 ? 30.091 46.977 -11.238 1.00 14.87 ? 250 ILE A CG2 1 ATOM 1892 C CD1 . ILE A 1 250 ? 31.114 48.495 -13.645 1.00 17.23 ? 250 ILE A CD1 1 ATOM 1893 N N . TRP A 1 251 ? 32.998 43.994 -13.511 1.00 14.94 ? 251 TRP A N 1 ATOM 1894 C CA . TRP A 1 251 ? 33.361 43.131 -14.628 1.00 15.86 ? 251 TRP A CA 1 ATOM 1895 C C . TRP A 1 251 ? 33.995 41.826 -14.204 1.00 20.78 ? 251 TRP A C 1 ATOM 1896 O O . TRP A 1 251 ? 34.340 41.021 -15.061 1.00 19.34 ? 251 TRP A O 1 ATOM 1897 C CB . TRP A 1 251 ? 34.360 43.854 -15.528 1.00 16.53 ? 251 TRP A CB 1 ATOM 1898 C CG . TRP A 1 251 ? 35.620 44.022 -14.831 1.00 20.81 ? 251 TRP A CG 1 ATOM 1899 C CD1 . TRP A 1 251 ? 36.593 43.055 -14.638 1.00 20.77 ? 251 TRP A CD1 1 ATOM 1900 C CD2 . TRP A 1 251 ? 36.050 45.164 -14.123 1.00 19.67 ? 251 TRP A CD2 1 ATOM 1901 N NE1 . TRP A 1 251 ? 37.577 43.539 -13.863 1.00 20.25 ? 251 TRP A NE1 1 ATOM 1902 C CE2 . TRP A 1 251 ? 37.283 44.832 -13.522 1.00 18.15 ? 251 TRP A CE2 1 ATOM 1903 C CE3 . TRP A 1 251 ? 35.515 46.431 -13.920 1.00 19.19 ? 251 TRP A CE3 1 ATOM 1904 C CZ2 . TRP A 1 251 ? 37.996 45.717 -12.728 1.00 17.31 ? 251 TRP A CZ2 1 ATOM 1905 C CZ3 . TRP A 1 251 ? 36.224 47.325 -13.120 1.00 19.76 ? 251 TRP A CZ3 1 ATOM 1906 C CH2 . TRP A 1 251 ? 37.456 46.957 -12.536 1.00 21.33 ? 251 TRP A CH2 1 ATOM 1907 N N . ASP A 1 252 ? 34.148 41.607 -12.901 1.00 16.87 ? 252 ASP A N 1 ATOM 1908 C CA . ASP A 1 252 ? 34.866 40.440 -12.393 1.00 18.82 ? 252 ASP A CA 1 ATOM 1909 C C . ASP A 1 252 ? 34.045 39.182 -12.291 1.00 18.80 ? 252 ASP A C 1 ATOM 1910 O O . ASP A 1 252 ? 33.278 38.965 -11.378 1.00 17.72 ? 252 ASP A O 1 ATOM 1911 C CB . ASP A 1 252 ? 35.486 40.839 -11.044 1.00 16.27 ? 252 ASP A CB 1 ATOM 1912 C CG . ASP A 1 252 ? 36.257 39.703 -10.398 1.00 20.27 ? 252 ASP A CG 1 ATOM 1913 O OD1 . ASP A 1 252 ? 36.525 38.708 -11.097 1.00 23.93 ? 252 ASP A OD1 1 ATOM 1914 O OD2 . ASP A 1 252 ? 36.587 39.818 -9.201 1.00 18.74 ? 252 ASP A OD2 1 ATOM 1915 N N . ASN A 1 253 ? 34.205 38.331 -13.293 1.00 21.03 ? 253 ASN A N 1 ATOM 1916 C CA . ASN A 1 253 ? 33.444 37.108 -13.369 1.00 21.53 ? 253 ASN A CA 1 ATOM 1917 C C . ASN A 1 253 ? 33.874 36.066 -12.334 1.00 19.23 ? 253 ASN A C 1 ATOM 1918 O O . ASN A 1 253 ? 33.030 35.393 -11.755 1.00 23.80 ? 253 ASN A O 1 ATOM 1919 C CB . ASN A 1 253 ? 33.618 36.548 -14.781 1.00 23.22 ? 253 ASN A CB 1 ATOM 1920 C CG . ASN A 1 253 ? 32.822 35.305 -15.011 1.00 30.08 ? 253 ASN A CG 1 ATOM 1921 O OD1 . ASN A 1 253 ? 33.347 34.322 -15.553 1.00 34.64 ? 253 ASN A OD1 1 ATOM 1922 N ND2 . ASN A 1 253 ? 31.550 35.324 -14.625 1.00 28.48 ? 253 ASN A ND2 1 ATOM 1923 N N . LYS A 1 254 ? 35.175 35.981 -12.113 1.00 22.72 ? 254 LYS A N 1 ATOM 1924 C CA . LYS A 1 254 ? 35.747 34.993 -11.192 1.00 24.70 ? 254 LYS A CA 1 ATOM 1925 C C . LYS A 1 254 ? 35.645 35.349 -9.725 1.00 24.43 ? 254 LYS A C 1 ATOM 1926 O O . LYS A 1 254 ? 35.463 34.471 -8.873 1.00 25.70 ? 254 LYS A O 1 ATOM 1927 C CB . LYS A 1 254 ? 37.219 34.772 -11.547 1.00 29.80 ? 254 LYS A CB 1 ATOM 1928 C CG . LYS A 1 254 ? 37.828 33.484 -11.002 1.00 35.70 ? 254 LYS A CG 1 ATOM 1929 C CD . LYS A 1 254 ? 39.225 33.246 -11.601 1.00 38.40 ? 254 LYS A CD 1 ATOM 1930 C CE . LYS A 1 254 ? 39.948 32.100 -10.864 1.00 39.49 ? 254 LYS A CE 1 ATOM 1931 N NZ . LYS A 1 254 ? 39.940 32.262 -9.372 1.00 40.20 ? 254 LYS A NZ 1 ATOM 1932 N N . GLY A 1 255 ? 35.765 36.639 -9.434 1.00 23.46 ? 255 GLY A N 1 ATOM 1933 C CA . GLY A 1 255 ? 35.705 37.101 -8.059 1.00 20.78 ? 255 GLY A CA 1 ATOM 1934 C C . GLY A 1 255 ? 37.069 37.361 -7.425 1.00 20.43 ? 255 GLY A C 1 ATOM 1935 O O . GLY A 1 255 ? 37.096 37.626 -6.227 1.00 20.04 ? 255 GLY A O 1 ATOM 1936 N N . ASP A 1 256 ? 38.180 37.340 -8.160 1.00 19.77 ? 256 ASP A N 1 ATOM 1937 C CA . ASP A 1 256 ? 39.467 37.561 -7.510 1.00 22.33 ? 256 ASP A CA 1 ATOM 1938 C C . ASP A 1 256 ? 39.676 38.961 -6.993 1.00 19.77 ? 256 ASP A C 1 ATOM 1939 O O . ASP A 1 256 ? 40.622 39.195 -6.239 1.00 20.71 ? 256 ASP A O 1 ATOM 1940 C CB . ASP A 1 256 ? 40.656 37.235 -8.427 1.00 27.25 ? 256 ASP A CB 1 ATOM 1941 C CG . ASP A 1 256 ? 40.608 35.830 -8.977 1.00 34.79 ? 256 ASP A CG 1 ATOM 1942 O OD1 . ASP A 1 256 ? 40.094 34.921 -8.273 1.00 37.58 ? 256 ASP A OD1 1 ATOM 1943 O OD2 . ASP A 1 256 ? 41.108 35.655 -10.117 1.00 37.71 ? 256 ASP A OD2 1 ATOM 1944 N N . THR A 1 257 ? 38.827 39.909 -7.397 1.00 15.63 ? 257 THR A N 1 ATOM 1945 C CA . THR A 1 257 ? 38.954 41.271 -6.867 1.00 16.09 ? 257 THR A CA 1 ATOM 1946 C C . THR A 1 257 ? 38.159 41.453 -5.564 1.00 16.49 ? 257 THR A C 1 ATOM 1947 O O . THR A 1 257 ? 38.276 42.524 -4.945 1.00 16.17 ? 257 THR A O 1 ATOM 1948 C CB . THR A 1 257 ? 38.422 42.347 -7.861 1.00 15.71 ? 257 THR A CB 1 ATOM 1949 O OG1 . THR A 1 257 ? 37.011 42.150 -8.062 1.00 15.06 ? 257 THR A OG1 1 ATOM 1950 C CG2 . THR A 1 257 ? 39.226 42.243 -9.218 1.00 17.09 ? 257 THR A CG2 1 ATOM 1951 N N . ALA A 1 258 ? 37.393 40.432 -5.152 1.00 15.80 ? 258 ALA A N 1 ATOM 1952 C CA . ALA A 1 258 ? 36.519 40.570 -3.979 1.00 14.06 ? 258 ALA A CA 1 ATOM 1953 C C . ALA A 1 258 ? 37.208 40.961 -2.696 1.00 13.80 ? 258 ALA A C 1 ATOM 1954 O O . ALA A 1 258 ? 38.309 40.469 -2.375 1.00 15.88 ? 258 ALA A O 1 ATOM 1955 C CB . ALA A 1 258 ? 35.764 39.316 -3.715 1.00 16.76 ? 258 ALA A CB 1 ATOM 1956 N N . LEU A 1 259 ? 36.542 41.855 -1.971 1.00 11.21 ? 259 LEU A N 1 ATOM 1957 C CA . LEU A 1 259 ? 37.043 42.302 -0.655 1.00 12.41 ? 259 LEU A CA 1 ATOM 1958 C C . LEU A 1 259 ? 35.863 42.289 0.265 1.00 12.49 ? 259 LEU A C 1 ATOM 1959 O O . LEU A 1 259 ? 34.803 42.877 -0.019 1.00 12.48 ? 259 LEU A O 1 ATOM 1960 C CB . LEU A 1 259 ? 37.614 43.723 -0.714 1.00 12.48 ? 259 LEU A CB 1 ATOM 1961 C CG . LEU A 1 259 ? 38.406 44.128 0.556 1.00 11.83 ? 259 LEU A CG 1 ATOM 1962 C CD1 . LEU A 1 259 ? 39.645 43.196 0.787 1.00 12.96 ? 259 LEU A CD1 1 ATOM 1963 C CD2 . LEU A 1 259 ? 38.858 45.623 0.414 1.00 14.79 ? 259 LEU A CD2 1 ATOM 1964 N N . PHE A 1 260 ? 36.036 41.648 1.424 1.00 12.66 ? 260 PHE A N 1 ATOM 1965 C CA . PHE A 1 260 ? 34.953 41.589 2.406 1.00 12.77 ? 260 PHE A CA 1 ATOM 1966 C C . PHE A 1 260 ? 34.630 42.990 2.895 1.00 11.82 ? 260 PHE A C 1 ATOM 1967 O O . PHE A 1 260 ? 35.542 43.732 3.322 1.00 12.12 ? 260 PHE A O 1 ATOM 1968 C CB . PHE A 1 260 ? 35.364 40.712 3.592 1.00 12.82 ? 260 PHE A CB 1 ATOM 1969 C CG . PHE A 1 260 ? 34.255 40.527 4.591 1.00 12.53 ? 260 PHE A CG 1 ATOM 1970 C CD1 . PHE A 1 260 ? 33.276 39.541 4.383 1.00 14.52 ? 260 PHE A CD1 1 ATOM 1971 C CD2 . PHE A 1 260 ? 34.167 41.323 5.715 1.00 13.00 ? 260 PHE A CD2 1 ATOM 1972 C CE1 . PHE A 1 260 ? 32.232 39.379 5.320 1.00 16.56 ? 260 PHE A CE1 1 ATOM 1973 C CE2 . PHE A 1 260 ? 33.133 41.178 6.634 1.00 15.34 ? 260 PHE A CE2 1 ATOM 1974 C CZ . PHE A 1 260 ? 32.174 40.210 6.437 1.00 14.36 ? 260 PHE A CZ 1 ATOM 1975 N N . THR A 1 261 ? 33.347 43.368 2.862 1.00 11.88 ? 261 THR A N 1 ATOM 1976 C CA . THR A 1 261 ? 32.924 44.716 3.211 1.00 11.40 ? 261 THR A CA 1 ATOM 1977 C C . THR A 1 261 ? 31.811 44.673 4.218 1.00 10.04 ? 261 THR A C 1 ATOM 1978 O O . THR A 1 261 ? 30.882 43.899 4.099 1.00 12.24 ? 261 THR A O 1 ATOM 1979 C CB . THR A 1 261 ? 32.412 45.427 1.937 1.00 12.53 ? 261 THR A CB 1 ATOM 1980 O OG1 . THR A 1 261 ? 33.475 45.467 0.978 1.00 12.08 ? 261 THR A OG1 1 ATOM 1981 C CG2 . THR A 1 261 ? 31.958 46.833 2.240 1.00 11.57 ? 261 THR A CG2 1 ATOM 1982 N N . HIS A 1 262 ? 31.911 45.543 5.215 1.00 11.52 ? 262 HIS A N 1 ATOM 1983 C CA . HIS A 1 262 ? 30.854 45.714 6.223 1.00 11.51 ? 262 HIS A CA 1 ATOM 1984 C C . HIS A 1 262 ? 30.204 47.084 6.029 1.00 12.12 ? 262 HIS A C 1 ATOM 1985 O O . HIS A 1 262 ? 30.917 48.113 6.098 1.00 11.86 ? 262 HIS A O 1 ATOM 1986 C CB . HIS A 1 262 ? 31.481 45.659 7.633 1.00 12.34 ? 262 HIS A CB 1 ATOM 1987 C CG . HIS A 1 262 ? 30.527 46.034 8.730 1.00 10.52 ? 262 HIS A CG 1 ATOM 1988 N ND1 . HIS A 1 262 ? 29.911 45.079 9.519 1.00 11.85 ? 262 HIS A ND1 1 ATOM 1989 C CD2 . HIS A 1 262 ? 30.084 47.243 9.176 1.00 11.34 ? 262 HIS A CD2 1 ATOM 1990 C CE1 . HIS A 1 262 ? 29.140 45.694 10.417 1.00 13.03 ? 262 HIS A CE1 1 ATOM 1991 N NE2 . HIS A 1 262 ? 29.219 46.999 10.233 1.00 13.29 ? 262 HIS A NE2 1 ATOM 1992 N N . MET A 1 263 ? 28.910 47.127 5.740 1.00 11.59 ? 263 MET A N 1 ATOM 1993 C CA . MET A 1 263 ? 28.217 48.395 5.674 1.00 11.39 ? 263 MET A CA 1 ATOM 1994 C C . MET A 1 263 ? 27.466 48.606 7.003 1.00 13.26 ? 263 MET A C 1 ATOM 1995 O O . MET A 1 263 ? 26.692 47.717 7.438 1.00 13.64 ? 263 MET A O 1 ATOM 1996 C CB . MET A 1 263 ? 27.187 48.384 4.526 1.00 13.36 ? 263 MET A CB 1 ATOM 1997 C CG . MET A 1 263 ? 26.369 49.684 4.422 1.00 12.43 ? 263 MET A CG 1 ATOM 1998 S SD . MET A 1 263 ? 25.025 49.508 3.176 1.00 13.39 ? 263 MET A SD 1 ATOM 1999 C CE . MET A 1 263 ? 25.907 49.084 1.679 1.00 14.29 ? 263 MET A CE 1 ATOM 2000 N N . MET A 1 264 ? 27.694 49.748 7.646 1.00 12.26 ? 264 MET A N 1 ATOM 2001 C CA . MET A 1 264 ? 26.986 50.069 8.890 1.00 13.02 ? 264 MET A CA 1 ATOM 2002 C C . MET A 1 264 ? 25.518 50.286 8.483 1.00 12.67 ? 264 MET A C 1 ATOM 2003 O O . MET A 1 264 ? 25.221 50.753 7.376 1.00 11.98 ? 264 MET A O 1 ATOM 2004 C CB A MET A 1 264 ? 27.595 51.305 9.528 0.50 11.76 ? 264 MET A CB 1 ATOM 2005 C CB B MET A 1 264 ? 27.647 51.145 9.652 0.50 12.74 ? 264 MET A CB 1 ATOM 2006 C CG A MET A 1 264 ? 29.016 51.052 9.953 0.50 10.91 ? 264 MET A CG 1 ATOM 2007 C CG B MET A 1 264 ? 29.024 50.672 10.079 0.50 16.52 ? 264 MET A CG 1 ATOM 2008 S SD A MET A 1 264 ? 30.022 52.524 10.435 0.50 15.66 ? 264 MET A SD 1 ATOM 2009 S SD B MET A 1 264 ? 29.688 51.501 11.537 0.50 17.60 ? 264 MET A SD 1 ATOM 2010 C CE A MET A 1 264 ? 28.960 53.414 11.493 0.50 13.65 ? 264 MET A CE 1 ATOM 2011 C CE B MET A 1 264 ? 30.165 52.910 10.593 0.50 20.08 ? 264 MET A CE 1 ATOM 2012 N N . PRO A 1 265 ? 24.570 49.949 9.375 1.00 14.51 ? 265 PRO A N 1 ATOM 2013 C CA . PRO A 1 265 ? 23.154 50.075 9.084 1.00 14.42 ? 265 PRO A CA 1 ATOM 2014 C C . PRO A 1 265 ? 22.342 51.291 9.288 1.00 14.33 ? 265 PRO A C 1 ATOM 2015 O O . PRO A 1 265 ? 21.265 51.407 8.708 1.00 14.83 ? 265 PRO A O 1 ATOM 2016 C CB . PRO A 1 265 ? 22.562 48.927 9.922 1.00 14.93 ? 265 PRO A CB 1 ATOM 2017 C CG . PRO A 1 265 ? 23.383 49.005 11.167 1.00 14.79 ? 265 PRO A CG 1 ATOM 2018 C CD . PRO A 1 265 ? 24.787 49.485 10.763 1.00 13.17 ? 265 PRO A CD 1 ATOM 2019 N N . PHE A 1 266 ? 22.885 52.205 10.068 1.00 14.30 ? 266 PHE A N 1 ATOM 2020 C CA . PHE A 1 266 ? 22.128 53.350 10.498 1.00 14.38 ? 266 PHE A CA 1 ATOM 2021 C C . PHE A 1 266 ? 22.480 54.682 9.908 1.00 14.14 ? 266 PHE A C 1 ATOM 2022 O O . PHE A 1 266 ? 23.355 54.780 9.080 1.00 14.69 ? 266 PHE A O 1 ATOM 2023 C CB . PHE A 1 266 ? 22.103 53.349 12.044 1.00 14.54 ? 266 PHE A CB 1 ATOM 2024 C CG . PHE A 1 266 ? 21.543 52.040 12.643 1.00 15.34 ? 266 PHE A CG 1 ATOM 2025 C CD1 . PHE A 1 266 ? 20.408 51.432 12.121 1.00 15.36 ? 266 PHE A CD1 1 ATOM 2026 C CD2 . PHE A 1 266 ? 22.173 51.446 13.722 1.00 14.12 ? 266 PHE A CD2 1 ATOM 2027 C CE1 . PHE A 1 266 ? 19.912 50.230 12.680 1.00 15.33 ? 266 PHE A CE1 1 ATOM 2028 C CE2 . PHE A 1 266 ? 21.691 50.252 14.295 1.00 15.24 ? 266 PHE A CE2 1 ATOM 2029 C CZ . PHE A 1 266 ? 20.548 49.651 13.748 1.00 14.55 ? 266 PHE A CZ 1 ATOM 2030 N N . TYR A 1 267 ? 21.802 55.706 10.345 1.00 14.64 ? 267 TYR A N 1 ATOM 2031 C CA . TYR A 1 267 ? 21.917 57.023 9.744 1.00 13.98 ? 267 TYR A CA 1 ATOM 2032 C C . TYR A 1 267 ? 23.247 57.754 9.935 1.00 13.28 ? 267 TYR A C 1 ATOM 2033 O O . TYR A 1 267 ? 23.626 58.576 9.095 1.00 14.41 ? 267 TYR A O 1 ATOM 2034 C CB . TYR A 1 267 ? 20.722 57.839 10.280 1.00 15.86 ? 267 TYR A CB 1 ATOM 2035 C CG . TYR A 1 267 ? 20.812 59.327 10.137 1.00 16.03 ? 267 TYR A CG 1 ATOM 2036 C CD1 . TYR A 1 267 ? 20.438 59.962 8.959 1.00 16.63 ? 267 TYR A CD1 1 ATOM 2037 C CD2 . TYR A 1 267 ? 21.231 60.110 11.216 1.00 18.63 ? 267 TYR A CD2 1 ATOM 2038 C CE1 . TYR A 1 267 ? 20.471 61.361 8.857 1.00 18.22 ? 267 TYR A CE1 1 ATOM 2039 C CE2 . TYR A 1 267 ? 21.267 61.505 11.120 1.00 19.34 ? 267 TYR A CE2 1 ATOM 2040 C CZ . TYR A 1 267 ? 20.881 62.109 9.950 1.00 19.08 ? 267 TYR A CZ 1 ATOM 2041 O OH . TYR A 1 267 ? 20.864 63.495 9.878 1.00 25.04 ? 267 TYR A OH 1 ATOM 2042 N N . SER A 1 268 ? 23.943 57.482 11.020 1.00 14.45 ? 268 SER A N 1 ATOM 2043 C CA . SER A 1 268 ? 25.193 58.164 11.319 1.00 13.15 ? 268 SER A CA 1 ATOM 2044 C C . SER A 1 268 ? 26.187 57.237 11.989 1.00 14.90 ? 268 SER A C 1 ATOM 2045 O O . SER A 1 268 ? 25.828 56.136 12.406 1.00 13.77 ? 268 SER A O 1 ATOM 2046 C CB . SER A 1 268 ? 24.876 59.358 12.233 1.00 16.46 ? 268 SER A CB 1 ATOM 2047 O OG . SER A 1 268 ? 26.042 60.028 12.659 1.00 16.94 ? 268 SER A OG 1 ATOM 2048 N N . TYR A 1 269 ? 27.458 57.650 12.034 1.00 14.22 ? 269 TYR A N 1 ATOM 2049 C CA . TYR A 1 269 ? 28.467 56.900 12.779 1.00 13.11 ? 269 TYR A CA 1 ATOM 2050 C C . TYR A 1 269 ? 28.572 57.397 14.253 1.00 13.26 ? 269 TYR A C 1 ATOM 2051 O O . TYR A 1 269 ? 29.428 56.907 14.998 1.00 13.57 ? 269 TYR A O 1 ATOM 2052 C CB . TYR A 1 269 ? 29.846 57.078 12.083 1.00 12.88 ? 269 TYR A CB 1 ATOM 2053 C CG . TYR A 1 269 ? 30.253 58.518 11.841 1.00 12.84 ? 269 TYR A CG 1 ATOM 2054 C CD1 . TYR A 1 269 ? 30.681 59.336 12.913 1.00 14.18 ? 269 TYR A CD1 1 ATOM 2055 C CD2 . TYR A 1 269 ? 30.181 59.073 10.554 1.00 14.34 ? 269 TYR A CD2 1 ATOM 2056 C CE1 . TYR A 1 269 ? 31.027 60.705 12.696 1.00 16.21 ? 269 TYR A CE1 1 ATOM 2057 C CE2 . TYR A 1 269 ? 30.528 60.414 10.339 1.00 13.50 ? 269 TYR A CE2 1 ATOM 2058 C CZ . TYR A 1 269 ? 30.937 61.204 11.410 1.00 16.37 ? 269 TYR A CZ 1 ATOM 2059 O OH . TYR A 1 269 ? 31.228 62.517 11.169 1.00 16.45 ? 269 TYR A OH 1 ATOM 2060 N N . ASP A 1 270 ? 27.730 58.354 14.653 1.00 13.50 ? 270 ASP A N 1 ATOM 2061 C CA . ASP A 1 270 ? 27.778 58.875 16.024 1.00 12.84 ? 270 ASP A CA 1 ATOM 2062 C C . ASP A 1 270 ? 27.206 57.848 16.992 1.00 14.80 ? 270 ASP A C 1 ATOM 2063 O O . ASP A 1 270 ? 26.636 56.823 16.584 1.00 14.82 ? 270 ASP A O 1 ATOM 2064 C CB . ASP A 1 270 ? 27.100 60.254 16.126 1.00 15.24 ? 270 ASP A CB 1 ATOM 2065 C CG . ASP A 1 270 ? 25.601 60.241 15.909 1.00 17.63 ? 270 ASP A CG 1 ATOM 2066 O OD1 . ASP A 1 270 ? 24.977 59.162 15.823 1.00 16.26 ? 270 ASP A OD1 1 ATOM 2067 O OD2 . ASP A 1 270 ? 25.034 61.367 15.854 1.00 20.12 ? 270 ASP A OD2 1 ATOM 2068 N N . ILE A 1 271 ? 27.427 58.085 18.281 1.00 14.33 ? 271 ILE A N 1 ATOM 2069 C CA . ILE A 1 271 ? 26.985 57.084 19.267 1.00 14.28 ? 271 ILE A CA 1 ATOM 2070 C C . ILE A 1 271 ? 25.485 56.812 19.229 1.00 14.22 ? 271 ILE A C 1 ATOM 2071 O O . ILE A 1 271 ? 25.095 55.655 19.229 1.00 14.44 ? 271 ILE A O 1 ATOM 2072 C CB . ILE A 1 271 ? 27.516 57.444 20.664 1.00 16.48 ? 271 ILE A CB 1 ATOM 2073 C CG1 . ILE A 1 271 ? 29.029 57.291 20.613 1.00 14.66 ? 271 ILE A CG1 1 ATOM 2074 C CG2 . ILE A 1 271 ? 26.987 56.443 21.728 1.00 13.57 ? 271 ILE A CG2 1 ATOM 2075 C CD1 . ILE A 1 271 ? 29.810 57.979 21.755 1.00 15.41 ? 271 ILE A CD1 1 ATOM 2076 N N . PRO A 1 272 ? 24.633 57.846 19.099 1.00 13.85 ? 272 PRO A N 1 ATOM 2077 C CA . PRO A 1 272 ? 23.182 57.562 19.045 1.00 15.66 ? 272 PRO A CA 1 ATOM 2078 C C . PRO A 1 272 ? 22.791 56.629 17.898 1.00 15.85 ? 272 PRO A C 1 ATOM 2079 O O . PRO A 1 272 ? 21.760 55.933 17.982 1.00 16.57 ? 272 PRO A O 1 ATOM 2080 C CB . PRO A 1 272 ? 22.530 58.936 18.852 1.00 14.76 ? 272 PRO A CB 1 ATOM 2081 C CG . PRO A 1 272 ? 23.529 59.909 19.498 1.00 16.54 ? 272 PRO A CG 1 ATOM 2082 C CD . PRO A 1 272 ? 24.914 59.298 19.204 1.00 15.00 ? 272 PRO A CD 1 ATOM 2083 N N . HIS A 1 273 ? 23.610 56.577 16.823 1.00 13.69 ? 273 HIS A N 1 ATOM 2084 C CA . HIS A 1 273 ? 23.242 55.714 15.679 1.00 13.55 ? 273 HIS A CA 1 ATOM 2085 C C . HIS A 1 273 ? 24.178 54.538 15.491 1.00 15.17 ? 273 HIS A C 1 ATOM 2086 O O . HIS A 1 273 ? 24.244 53.944 14.406 1.00 15.84 ? 273 HIS A O 1 ATOM 2087 C CB . HIS A 1 273 ? 23.115 56.565 14.385 1.00 12.88 ? 273 HIS A CB 1 ATOM 2088 C CG . HIS A 1 273 ? 22.115 57.681 14.518 1.00 14.77 ? 273 HIS A CG 1 ATOM 2089 N ND1 . HIS A 1 273 ? 20.780 57.585 14.176 1.00 18.45 ? 273 HIS A ND1 1 ATOM 2090 C CD2 . HIS A 1 273 ? 22.281 58.922 15.026 1.00 12.38 ? 273 HIS A CD2 1 ATOM 2091 C CE1 . HIS A 1 273 ? 20.171 58.720 14.475 1.00 12.65 ? 273 HIS A CE1 1 ATOM 2092 N NE2 . HIS A 1 273 ? 21.057 59.548 14.997 1.00 17.57 ? 273 HIS A NE2 1 ATOM 2093 N N . THR A 1 274 ? 24.866 54.135 16.555 1.00 13.83 ? 274 THR A N 1 ATOM 2094 C CA . THR A 1 274 ? 25.746 52.987 16.416 1.00 12.84 ? 274 THR A CA 1 ATOM 2095 C C . THR A 1 274 ? 25.526 51.912 17.476 1.00 14.21 ? 274 THR A C 1 ATOM 2096 O O . THR A 1 274 ? 26.041 50.822 17.346 1.00 15.97 ? 274 THR A O 1 ATOM 2097 C CB . THR A 1 274 ? 27.238 53.392 16.401 1.00 15.09 ? 274 THR A CB 1 ATOM 2098 O OG1 . THR A 1 274 ? 27.494 54.317 17.464 1.00 15.23 ? 274 THR A OG1 1 ATOM 2099 C CG2 . THR A 1 274 ? 27.602 54.031 15.084 1.00 14.68 ? 274 THR A CG2 1 ATOM 2100 N N . CYS A 1 275 ? 24.746 52.184 18.530 1.00 14.65 ? 275 CYS A N 1 ATOM 2101 C CA . CYS A 1 275 ? 24.562 51.097 19.496 1.00 16.52 ? 275 CYS A CA 1 ATOM 2102 C C . CYS A 1 275 ? 23.407 50.155 19.136 1.00 16.66 ? 275 CYS A C 1 ATOM 2103 O O . CYS A 1 275 ? 23.355 49.005 19.590 1.00 16.79 ? 275 CYS A O 1 ATOM 2104 C CB . CYS A 1 275 ? 24.289 51.682 20.894 1.00 17.59 ? 275 CYS A CB 1 ATOM 2105 S SG . CYS A 1 275 ? 22.561 51.780 21.507 1.00 18.94 ? 275 CYS A SG 1 ATOM 2106 N N . GLY A 1 276 ? 22.498 50.636 18.309 1.00 16.18 ? 276 GLY A N 1 ATOM 2107 C CA . GLY A 1 276 ? 21.295 49.879 17.997 1.00 16.24 ? 276 GLY A CA 1 ATOM 2108 C C . GLY A 1 276 ? 20.357 50.776 17.232 1.00 15.86 ? 276 GLY A C 1 ATOM 2109 O O . GLY A 1 276 ? 20.701 51.932 16.972 1.00 15.99 ? 276 GLY A O 1 ATOM 2110 N N . PRO A 1 277 ? 19.136 50.323 16.912 1.00 16.09 ? 277 PRO A N 1 ATOM 2111 C CA . PRO A 1 277 ? 18.172 51.096 16.140 1.00 16.44 ? 277 PRO A CA 1 ATOM 2112 C C . PRO A 1 277 ? 17.477 52.303 16.736 1.00 15.39 ? 277 PRO A C 1 ATOM 2113 O O . PRO A 1 277 ? 16.883 53.091 15.998 1.00 17.01 ? 277 PRO A O 1 ATOM 2114 C CB . PRO A 1 277 ? 17.138 50.047 15.723 1.00 17.38 ? 277 PRO A CB 1 ATOM 2115 C CG . PRO A 1 277 ? 17.129 49.113 16.940 1.00 15.22 ? 277 PRO A CG 1 ATOM 2116 C CD . PRO A 1 277 ? 18.598 48.983 17.262 1.00 17.37 ? 277 PRO A CD 1 ATOM 2117 N N . ASP A 1 278 ? 17.553 52.445 18.053 1.00 17.27 ? 278 ASP A N 1 ATOM 2118 C CA . ASP A 1 278 ? 16.820 53.550 18.701 1.00 17.29 ? 278 ASP A CA 1 ATOM 2119 C C . ASP A 1 278 ? 17.754 54.583 19.253 1.00 16.12 ? 278 ASP A C 1 ATOM 2120 O O . ASP A 1 278 ? 18.325 54.406 20.314 1.00 18.06 ? 278 ASP A O 1 ATOM 2121 C CB . ASP A 1 278 ? 15.932 52.993 19.833 1.00 17.95 ? 278 ASP A CB 1 ATOM 2122 C CG . ASP A 1 278 ? 15.043 54.060 20.438 1.00 20.99 ? 278 ASP A CG 1 ATOM 2123 O OD1 . ASP A 1 278 ? 15.168 55.250 20.092 1.00 21.34 ? 278 ASP A OD1 1 ATOM 2124 O OD2 . ASP A 1 278 ? 14.193 53.707 21.275 1.00 21.87 ? 278 ASP A OD2 1 ATOM 2125 N N . PRO A 1 279 ? 17.893 55.701 18.535 1.00 17.93 ? 279 PRO A N 1 ATOM 2126 C CA . PRO A 1 279 ? 18.805 56.757 19.000 1.00 17.93 ? 279 PRO A CA 1 ATOM 2127 C C . PRO A 1 279 ? 18.475 57.369 20.334 1.00 16.50 ? 279 PRO A C 1 ATOM 2128 O O . PRO A 1 279 ? 19.385 57.803 21.035 1.00 18.35 ? 279 PRO A O 1 ATOM 2129 C CB . PRO A 1 279 ? 18.795 57.778 17.859 1.00 19.31 ? 279 PRO A CB 1 ATOM 2130 C CG . PRO A 1 279 ? 17.426 57.640 17.290 1.00 18.71 ? 279 PRO A CG 1 ATOM 2131 C CD . PRO A 1 279 ? 17.086 56.134 17.380 1.00 16.90 ? 279 PRO A CD 1 ATOM 2132 N N . LYS A 1 280 ? 17.191 57.351 20.721 1.00 17.86 ? 280 LYS A N 1 ATOM 2133 C CA . LYS A 1 280 ? 16.818 57.917 22.021 1.00 19.32 ? 280 LYS A CA 1 ATOM 2134 C C . LYS A 1 280 ? 17.427 57.081 23.134 1.00 18.30 ? 280 LYS A C 1 ATOM 2135 O O . LYS A 1 280 ? 17.825 57.604 24.183 1.00 20.61 ? 280 LYS A O 1 ATOM 2136 C CB . LYS A 1 280 ? 15.306 57.978 22.135 1.00 21.53 ? 280 LYS A CB 1 ATOM 2137 C CG . LYS A 1 280 ? 14.795 58.271 23.539 1.00 24.10 ? 280 LYS A CG 1 ATOM 2138 C CD . LYS A 1 280 ? 13.345 58.754 23.413 1.00 29.82 ? 280 LYS A CD 1 ATOM 2139 C CE . LYS A 1 280 ? 12.465 58.243 24.523 1.00 36.34 ? 280 LYS A CE 1 ATOM 2140 N NZ . LYS A 1 280 ? 13.292 57.755 25.664 1.00 40.36 ? 280 LYS A NZ 1 ATOM 2141 N N . VAL A 1 281 ? 17.569 55.774 22.902 1.00 17.97 ? 281 VAL A N 1 ATOM 2142 C CA . VAL A 1 281 ? 18.212 54.909 23.880 1.00 17.02 ? 281 VAL A CA 1 ATOM 2143 C C . VAL A 1 281 ? 19.745 54.971 23.765 1.00 17.36 ? 281 VAL A C 1 ATOM 2144 O O . VAL A 1 281 ? 20.477 55.124 24.756 1.00 17.72 ? 281 VAL A O 1 ATOM 2145 C CB . VAL A 1 281 ? 17.772 53.434 23.708 1.00 17.95 ? 281 VAL A CB 1 ATOM 2146 C CG1 . VAL A 1 281 ? 18.605 52.512 24.652 1.00 17.32 ? 281 VAL A CG1 1 ATOM 2147 C CG2 . VAL A 1 281 ? 16.246 53.338 23.959 1.00 18.19 ? 281 VAL A CG2 1 ATOM 2148 N N . CYS A 1 282 ? 20.249 54.887 22.529 1.00 17.77 ? 282 CYS A N 1 ATOM 2149 C CA . CYS A 1 282 ? 21.697 54.882 22.373 1.00 17.52 ? 282 CYS A CA 1 ATOM 2150 C C . CYS A 1 282 ? 22.388 56.165 22.859 1.00 15.26 ? 282 CYS A C 1 ATOM 2151 O O . CYS A 1 282 ? 23.524 56.112 23.363 1.00 16.78 ? 282 CYS A O 1 ATOM 2152 C CB . CYS A 1 282 ? 22.088 54.683 20.897 1.00 16.62 ? 282 CYS A CB 1 ATOM 2153 S SG . CYS A 1 282 ? 21.659 53.068 20.214 1.00 18.37 ? 282 CYS A SG 1 ATOM 2154 N N . CYS A 1 283 ? 21.684 57.285 22.700 1.00 17.41 ? 283 CYS A N 1 ATOM 2155 C CA . CYS A 1 283 ? 22.239 58.549 23.114 1.00 16.49 ? 283 CYS A CA 1 ATOM 2156 C C . CYS A 1 283 ? 22.541 58.516 24.604 1.00 15.81 ? 283 CYS A C 1 ATOM 2157 O O . CYS A 1 283 ? 23.437 59.189 25.061 1.00 15.43 ? 283 CYS A O 1 ATOM 2158 C CB . CYS A 1 283 ? 21.261 59.666 22.770 1.00 17.04 ? 283 CYS A CB 1 ATOM 2159 S SG . CYS A 1 283 ? 22.087 61.297 22.880 1.00 20.34 ? 283 CYS A SG 1 ATOM 2160 N N . GLN A 1 284 ? 21.782 57.702 25.366 1.00 16.55 ? 284 GLN A N 1 ATOM 2161 C CA . GLN A 1 284 ? 22.027 57.602 26.803 1.00 17.07 ? 284 GLN A CA 1 ATOM 2162 C C . GLN A 1 284 ? 23.298 56.843 27.177 1.00 15.39 ? 284 GLN A C 1 ATOM 2163 O O . GLN A 1 284 ? 23.653 56.735 28.337 1.00 18.32 ? 284 GLN A O 1 ATOM 2164 C CB . GLN A 1 284 ? 20.823 56.930 27.497 1.00 18.26 ? 284 GLN A CB 1 ATOM 2165 C CG . GLN A 1 284 ? 19.519 57.648 27.285 1.00 18.34 ? 284 GLN A CG 1 ATOM 2166 C CD . GLN A 1 284 ? 18.360 56.860 27.842 1.00 20.11 ? 284 GLN A CD 1 ATOM 2167 O OE1 . GLN A 1 284 ? 18.391 56.465 29.006 1.00 22.19 ? 284 GLN A OE1 1 ATOM 2168 N NE2 . GLN A 1 284 ? 17.344 56.630 27.028 1.00 20.51 ? 284 GLN A NE2 1 ATOM 2169 N N . PHE A 1 285 ? 24.007 56.336 26.154 1.00 15.89 ? 285 PHE A N 1 ATOM 2170 C CA . PHE A 1 285 ? 25.237 55.616 26.348 1.00 15.17 ? 285 PHE A CA 1 ATOM 2171 C C . PHE A 1 285 ? 26.413 56.366 25.719 1.00 14.47 ? 285 PHE A C 1 ATOM 2172 O O . PHE A 1 285 ? 27.481 55.798 25.467 1.00 16.53 ? 285 PHE A O 1 ATOM 2173 C CB . PHE A 1 285 ? 25.096 54.155 25.893 1.00 16.67 ? 285 PHE A CB 1 ATOM 2174 C CG . PHE A 1 285 ? 24.096 53.391 26.746 1.00 16.67 ? 285 PHE A CG 1 ATOM 2175 C CD1 . PHE A 1 285 ? 24.478 52.785 27.943 1.00 18.54 ? 285 PHE A CD1 1 ATOM 2176 C CD2 . PHE A 1 285 ? 22.760 53.397 26.386 1.00 16.49 ? 285 PHE A CD2 1 ATOM 2177 C CE1 . PHE A 1 285 ? 23.508 52.195 28.786 1.00 19.27 ? 285 PHE A CE1 1 ATOM 2178 C CE2 . PHE A 1 285 ? 21.773 52.804 27.238 1.00 20.36 ? 285 PHE A CE2 1 ATOM 2179 C CZ . PHE A 1 285 ? 22.164 52.217 28.423 1.00 19.00 ? 285 PHE A CZ 1 ATOM 2180 N N . ASP A 1 286 ? 26.162 57.637 25.448 1.00 14.82 ? 286 ASP A N 1 ATOM 2181 C CA . ASP A 1 286 ? 27.234 58.548 25.021 1.00 15.73 ? 286 ASP A CA 1 ATOM 2182 C C . ASP A 1 286 ? 27.477 59.377 26.308 1.00 14.79 ? 286 ASP A C 1 ATOM 2183 O O . ASP A 1 286 ? 26.800 60.390 26.541 1.00 15.79 ? 286 ASP A O 1 ATOM 2184 C CB . ASP A 1 286 ? 26.797 59.438 23.880 1.00 15.61 ? 286 ASP A CB 1 ATOM 2185 C CG . ASP A 1 286 ? 27.941 60.337 23.382 1.00 14.15 ? 286 ASP A CG 1 ATOM 2186 O OD1 . ASP A 1 286 ? 28.978 60.402 24.090 1.00 14.54 ? 286 ASP A OD1 1 ATOM 2187 O OD2 . ASP A 1 286 ? 27.749 60.977 22.329 1.00 15.33 ? 286 ASP A OD2 1 ATOM 2188 N N . PHE A 1 287 ? 28.453 58.967 27.104 1.00 14.14 ? 287 PHE A N 1 ATOM 2189 C CA . PHE A 1 287 ? 28.614 59.616 28.396 1.00 15.16 ? 287 PHE A CA 1 ATOM 2190 C C . PHE A 1 287 ? 29.183 61.008 28.365 1.00 17.37 ? 287 PHE A C 1 ATOM 2191 O O . PHE A 1 287 ? 29.315 61.653 29.411 1.00 18.35 ? 287 PHE A O 1 ATOM 2192 C CB . PHE A 1 287 ? 29.342 58.673 29.362 1.00 16.47 ? 287 PHE A CB 1 ATOM 2193 C CG . PHE A 1 287 ? 28.551 57.384 29.625 1.00 15.94 ? 287 PHE A CG 1 ATOM 2194 C CD1 . PHE A 1 287 ? 27.548 57.362 30.614 1.00 17.13 ? 287 PHE A CD1 1 ATOM 2195 C CD2 . PHE A 1 287 ? 28.770 56.223 28.894 1.00 16.67 ? 287 PHE A CD2 1 ATOM 2196 C CE1 . PHE A 1 287 ? 26.793 56.211 30.854 1.00 17.98 ? 287 PHE A CE1 1 ATOM 2197 C CE2 . PHE A 1 287 ? 28.014 55.060 29.134 1.00 19.32 ? 287 PHE A CE2 1 ATOM 2198 C CZ . PHE A 1 287 ? 27.014 55.059 30.129 1.00 16.93 ? 287 PHE A CZ 1 ATOM 2199 N N . LYS A 1 288 ? 29.502 61.513 27.171 1.00 16.86 ? 288 LYS A N 1 ATOM 2200 C CA . LYS A 1 288 ? 29.958 62.898 27.096 1.00 17.39 ? 288 LYS A CA 1 ATOM 2201 C C . LYS A 1 288 ? 28.740 63.835 27.018 1.00 18.43 ? 288 LYS A C 1 ATOM 2202 O O . LYS A 1 288 ? 28.904 65.050 26.937 1.00 19.39 ? 288 LYS A O 1 ATOM 2203 C CB . LYS A 1 288 ? 30.822 63.102 25.819 1.00 17.62 ? 288 LYS A CB 1 ATOM 2204 C CG . LYS A 1 288 ? 31.709 64.379 25.850 1.00 14.27 ? 288 LYS A CG 1 ATOM 2205 C CD . LYS A 1 288 ? 32.523 64.527 24.544 1.00 14.05 ? 288 LYS A CD 1 ATOM 2206 C CE . LYS A 1 288 ? 33.366 65.765 24.731 1.00 15.62 ? 288 LYS A CE 1 ATOM 2207 N NZ . LYS A 1 288 ? 34.279 65.958 23.497 1.00 19.06 ? 288 LYS A NZ 1 ATOM 2208 N N . ARG A 1 289 ? 27.511 63.301 27.018 1.00 17.79 ? 289 ARG A N 1 ATOM 2209 C CA . ARG A 1 289 ? 26.324 64.142 26.885 1.00 20.59 ? 289 ARG A CA 1 ATOM 2210 C C . ARG A 1 289 ? 25.514 64.444 28.172 1.00 21.09 ? 289 ARG A C 1 ATOM 2211 O O . ARG A 1 289 ? 24.319 64.699 28.075 1.00 22.32 ? 289 ARG A O 1 ATOM 2212 C CB . ARG A 1 289 ? 25.370 63.522 25.848 1.00 18.62 ? 289 ARG A CB 1 ATOM 2213 C CG . ARG A 1 289 ? 26.005 63.356 24.471 1.00 16.77 ? 289 ARG A CG 1 ATOM 2214 C CD . ARG A 1 289 ? 24.996 62.908 23.494 1.00 16.20 ? 289 ARG A CD 1 ATOM 2215 N NE . ARG A 1 289 ? 25.558 62.601 22.167 1.00 16.51 ? 289 ARG A NE 1 ATOM 2216 C CZ . ARG A 1 289 ? 25.111 63.131 21.041 1.00 17.77 ? 289 ARG A CZ 1 ATOM 2217 N NH1 . ARG A 1 289 ? 24.118 64.018 21.005 1.00 19.18 ? 289 ARG A NH1 1 ATOM 2218 N NH2 . ARG A 1 289 ? 25.660 62.727 19.893 1.00 16.64 ? 289 ARG A NH2 1 ATOM 2219 N N . MET A 1 290 ? 26.147 64.452 29.343 1.00 25.55 ? 290 MET A N 1 ATOM 2220 C CA . MET A 1 290 ? 25.375 64.717 30.560 1.00 27.57 ? 290 MET A CA 1 ATOM 2221 C C . MET A 1 290 ? 25.339 66.212 30.968 1.00 30.34 ? 290 MET A C 1 ATOM 2222 O O . MET A 1 290 ? 24.592 66.594 31.917 1.00 32.00 ? 290 MET A O 1 ATOM 2223 C CB . MET A 1 290 ? 25.863 63.809 31.718 1.00 25.50 ? 290 MET A CB 1 ATOM 2224 C CG . MET A 1 290 ? 25.875 62.330 31.364 1.00 25.89 ? 290 MET A CG 1 ATOM 2225 S SD . MET A 1 290 ? 26.258 61.209 32.772 1.00 27.84 ? 290 MET A SD 1 ATOM 2226 C CE . MET A 1 290 ? 28.040 61.070 32.683 1.00 29.89 ? 290 MET A CE 1 ATOM 2227 N N . GLY A 1 291 ? 26.108 67.059 30.265 1.00 29.02 ? 291 GLY A N 1 ATOM 2228 C CA . GLY A 1 291 ? 26.077 68.488 30.556 1.00 28.10 ? 291 GLY A CA 1 ATOM 2229 C C . GLY A 1 291 ? 27.348 69.339 30.645 1.00 28.01 ? 291 GLY A C 1 ATOM 2230 O O . GLY A 1 291 ? 27.438 70.414 30.021 1.00 26.93 ? 291 GLY A O 1 ATOM 2231 N N . SER A 1 292 ? 28.331 68.871 31.414 1.00 25.86 ? 292 SER A N 1 ATOM 2232 C CA . SER A 1 292 ? 29.559 69.626 31.622 1.00 22.10 ? 292 SER A CA 1 ATOM 2233 C C . SER A 1 292 ? 30.416 69.818 30.358 1.00 21.09 ? 292 SER A C 1 ATOM 2234 O O . SER A 1 292 ? 31.315 70.675 30.328 1.00 19.77 ? 292 SER A O 1 ATOM 2235 C CB . SER A 1 292 ? 30.382 68.942 32.703 1.00 23.29 ? 292 SER A CB 1 ATOM 2236 O OG . SER A 1 292 ? 30.815 67.671 32.236 1.00 24.32 ? 292 SER A OG 1 ATOM 2237 N N . PHE A 1 293 ? 30.132 69.024 29.325 1.00 19.17 ? 293 PHE A N 1 ATOM 2238 C CA . PHE A 1 293 ? 30.871 69.122 28.058 1.00 16.97 ? 293 PHE A CA 1 ATOM 2239 C C . PHE A 1 293 ? 30.099 69.938 27.043 1.00 18.20 ? 293 PHE A C 1 ATOM 2240 O O . PHE A 1 293 ? 30.536 70.036 25.896 1.00 19.25 ? 293 PHE A O 1 ATOM 2241 C CB . PHE A 1 293 ? 31.125 67.710 27.456 1.00 17.49 ? 293 PHE A CB 1 ATOM 2242 C CG . PHE A 1 293 ? 32.050 66.867 28.262 1.00 16.77 ? 293 PHE A CG 1 ATOM 2243 C CD1 . PHE A 1 293 ? 33.405 67.012 28.137 1.00 17.97 ? 293 PHE A CD1 1 ATOM 2244 C CD2 . PHE A 1 293 ? 31.537 65.943 29.151 1.00 18.09 ? 293 PHE A CD2 1 ATOM 2245 C CE1 . PHE A 1 293 ? 34.289 66.224 28.894 1.00 19.75 ? 293 PHE A CE1 1 ATOM 2246 C CE2 . PHE A 1 293 ? 32.416 65.136 29.929 1.00 18.94 ? 293 PHE A CE2 1 ATOM 2247 C CZ . PHE A 1 293 ? 33.778 65.292 29.781 1.00 19.54 ? 293 PHE A CZ 1 ATOM 2248 N N . GLY A 1 294 ? 28.959 70.493 27.469 1.00 18.33 ? 294 GLY A N 1 ATOM 2249 C CA . GLY A 1 294 ? 28.156 71.288 26.565 1.00 19.81 ? 294 GLY A CA 1 ATOM 2250 C C . GLY A 1 294 ? 27.451 70.487 25.490 1.00 19.22 ? 294 GLY A C 1 ATOM 2251 O O . GLY A 1 294 ? 27.120 71.019 24.424 1.00 22.16 ? 294 GLY A O 1 ATOM 2252 N N . LEU A 1 295 ? 27.244 69.202 25.756 1.00 19.34 ? 295 LEU A N 1 ATOM 2253 C CA . LEU A 1 295 ? 26.524 68.356 24.827 1.00 18.01 ? 295 LEU A CA 1 ATOM 2254 C C . LEU A 1 295 ? 25.299 67.835 25.548 1.00 19.10 ? 295 LEU A C 1 ATOM 2255 O O . LEU A 1 295 ? 25.283 67.756 26.762 1.00 20.00 ? 295 LEU A O 1 ATOM 2256 C CB . LEU A 1 295 ? 27.391 67.179 24.361 1.00 19.74 ? 295 LEU A CB 1 ATOM 2257 C CG . LEU A 1 295 ? 28.670 67.597 23.590 1.00 21.23 ? 295 LEU A CG 1 ATOM 2258 C CD1 . LEU A 1 295 ? 29.525 66.374 23.289 1.00 22.94 ? 295 LEU A CD1 1 ATOM 2259 C CD2 . LEU A 1 295 ? 28.305 68.327 22.275 1.00 22.98 ? 295 LEU A CD2 1 ATOM 2260 N N . SER A 1 296 ? 24.294 67.474 24.765 1.00 19.76 ? 296 SER A N 1 ATOM 2261 C CA . SER A 1 296 ? 23.042 66.916 25.310 1.00 21.94 ? 296 SER A CA 1 ATOM 2262 C C . SER A 1 296 ? 22.442 65.954 24.303 1.00 22.53 ? 296 SER A C 1 ATOM 2263 O O . SER A 1 296 ? 22.969 65.806 23.196 1.00 21.12 ? 296 SER A O 1 ATOM 2264 C CB . SER A 1 296 ? 22.061 68.070 25.624 1.00 20.40 ? 296 SER A CB 1 ATOM 2265 O OG . SER A 1 296 ? 21.752 68.835 24.477 1.00 24.61 ? 296 SER A OG 1 ATOM 2266 N N . CYS A 1 297 ? 21.355 65.275 24.681 1.00 22.42 ? 297 CYS A N 1 ATOM 2267 C CA . CYS A 1 297 ? 20.666 64.329 23.795 1.00 21.81 ? 297 CYS A CA 1 ATOM 2268 C C . CYS A 1 297 ? 19.432 64.972 23.210 1.00 21.82 ? 297 CYS A C 1 ATOM 2269 O O . CYS A 1 297 ? 18.530 65.340 23.967 1.00 23.94 ? 297 CYS A O 1 ATOM 2270 C CB . CYS A 1 297 ? 20.263 63.068 24.583 1.00 23.65 ? 297 CYS A CB 1 ATOM 2271 S SG . CYS A 1 297 ? 21.674 61.927 24.827 1.00 25.35 ? 297 CYS A SG 1 ATOM 2272 N N . PRO A 1 298 ? 19.341 65.088 21.876 1.00 22.04 ? 298 PRO A N 1 ATOM 2273 C CA . PRO A 1 298 ? 18.150 65.723 21.302 1.00 23.25 ? 298 PRO A CA 1 ATOM 2274 C C . PRO A 1 298 ? 16.854 64.980 21.545 1.00 22.38 ? 298 PRO A C 1 ATOM 2275 O O . PRO A 1 298 ? 15.775 65.590 21.475 1.00 23.48 ? 298 PRO A O 1 ATOM 2276 C CB . PRO A 1 298 ? 18.488 65.883 19.811 1.00 26.66 ? 298 PRO A CB 1 ATOM 2277 C CG . PRO A 1 298 ? 19.604 64.937 19.570 1.00 24.92 ? 298 PRO A CG 1 ATOM 2278 C CD . PRO A 1 298 ? 20.390 64.890 20.846 1.00 21.40 ? 298 PRO A CD 1 ATOM 2279 N N . TRP A 1 299 ? 16.972 63.699 21.890 1.00 20.80 ? 299 TRP A N 1 ATOM 2280 C CA . TRP A 1 299 ? 15.776 62.874 22.148 1.00 21.79 ? 299 TRP A CA 1 ATOM 2281 C C . TRP A 1 299 ? 15.273 63.099 23.565 1.00 24.39 ? 299 TRP A C 1 ATOM 2282 O O . TRP A 1 299 ? 14.339 62.433 24.028 1.00 23.93 ? 299 TRP A O 1 ATOM 2283 C CB . TRP A 1 299 ? 16.074 61.390 21.876 1.00 20.18 ? 299 TRP A CB 1 ATOM 2284 C CG . TRP A 1 299 ? 16.412 61.169 20.428 1.00 19.69 ? 299 TRP A CG 1 ATOM 2285 C CD1 . TRP A 1 299 ? 15.548 60.980 19.396 1.00 19.87 ? 299 TRP A CD1 1 ATOM 2286 C CD2 . TRP A 1 299 ? 17.726 61.258 19.847 1.00 17.64 ? 299 TRP A CD2 1 ATOM 2287 N NE1 . TRP A 1 299 ? 16.242 60.950 18.201 1.00 21.28 ? 299 TRP A NE1 1 ATOM 2288 C CE2 . TRP A 1 299 ? 17.576 61.122 18.462 1.00 20.23 ? 299 TRP A CE2 1 ATOM 2289 C CE3 . TRP A 1 299 ? 19.004 61.442 20.381 1.00 20.48 ? 299 TRP A CE3 1 ATOM 2290 C CZ2 . TRP A 1 299 ? 18.668 61.167 17.583 1.00 19.06 ? 299 TRP A CZ2 1 ATOM 2291 C CZ3 . TRP A 1 299 ? 20.087 61.479 19.510 1.00 18.71 ? 299 TRP A CZ3 1 ATOM 2292 C CH2 . TRP A 1 299 ? 19.897 61.344 18.125 1.00 19.56 ? 299 TRP A CH2 1 ATOM 2293 N N . LYS A 1 300 ? 15.949 64.005 24.265 1.00 24.27 ? 300 LYS A N 1 ATOM 2294 C CA . LYS A 1 300 ? 15.519 64.449 25.593 1.00 26.58 ? 300 LYS A CA 1 ATOM 2295 C C . LYS A 1 300 ? 15.705 63.567 26.817 1.00 26.81 ? 300 LYS A C 1 ATOM 2296 O O . LYS A 1 300 ? 15.188 63.882 27.893 1.00 28.29 ? 300 LYS A O 1 ATOM 2297 C CB . LYS A 1 300 ? 14.056 64.895 25.505 1.00 27.93 ? 300 LYS A CB 1 ATOM 2298 C CG . LYS A 1 300 ? 13.809 66.067 24.595 1.00 30.93 ? 300 LYS A CG 1 ATOM 2299 C CD . LYS A 1 300 ? 12.313 66.347 24.449 1.00 34.44 ? 300 LYS A CD 1 ATOM 2300 C CE . LYS A 1 300 ? 12.040 67.716 23.833 1.00 37.67 ? 300 LYS A CE 1 ATOM 2301 N NZ . LYS A 1 300 ? 12.768 67.911 22.537 1.00 39.12 ? 300 LYS A NZ 1 ATOM 2302 N N . VAL A 1 301 ? 16.399 62.451 26.677 1.00 24.91 ? 301 VAL A N 1 ATOM 2303 C CA . VAL A 1 301 ? 16.666 61.605 27.817 1.00 23.74 ? 301 VAL A CA 1 ATOM 2304 C C . VAL A 1 301 ? 18.176 61.606 27.891 1.00 23.91 ? 301 VAL A C 1 ATOM 2305 O O . VAL A 1 301 ? 18.848 61.122 26.979 1.00 24.80 ? 301 VAL A O 1 ATOM 2306 C CB . VAL A 1 301 ? 16.158 60.157 27.643 1.00 25.58 ? 301 VAL A CB 1 ATOM 2307 C CG1 . VAL A 1 301 ? 16.449 59.377 28.918 1.00 25.03 ? 301 VAL A CG1 1 ATOM 2308 C CG2 . VAL A 1 301 ? 14.658 60.142 27.341 1.00 26.91 ? 301 VAL A CG2 1 ATOM 2309 N N . PRO A 1 302 ? 18.744 62.118 28.978 1.00 22.43 ? 302 PRO A N 1 ATOM 2310 C CA . PRO A 1 302 ? 20.188 62.165 29.092 1.00 22.72 ? 302 PRO A CA 1 ATOM 2311 C C . PRO A 1 302 ? 20.849 60.895 29.555 1.00 22.07 ? 302 PRO A C 1 ATOM 2312 O O . PRO A 1 302 ? 20.212 59.970 30.069 1.00 22.97 ? 302 PRO A O 1 ATOM 2313 C CB . PRO A 1 302 ? 20.398 63.300 30.082 1.00 25.48 ? 302 PRO A CB 1 ATOM 2314 C CG . PRO A 1 302 ? 19.256 63.065 31.071 1.00 25.10 ? 302 PRO A CG 1 ATOM 2315 C CD . PRO A 1 302 ? 18.098 62.763 30.147 1.00 21.46 ? 302 PRO A CD 1 ATOM 2316 N N . PRO A 1 303 ? 22.166 60.801 29.340 1.00 20.35 ? 303 PRO A N 1 ATOM 2317 C CA . PRO A 1 303 ? 22.854 59.602 29.802 1.00 20.06 ? 303 PRO A CA 1 ATOM 2318 C C . PRO A 1 303 ? 22.852 59.726 31.325 1.00 22.08 ? 303 PRO A C 1 ATOM 2319 O O . PRO A 1 303 ? 22.746 60.830 31.867 1.00 21.29 ? 303 PRO A O 1 ATOM 2320 C CB . PRO A 1 303 ? 24.299 59.771 29.298 1.00 19.93 ? 303 PRO A CB 1 ATOM 2321 C CG . PRO A 1 303 ? 24.243 60.937 28.326 1.00 22.59 ? 303 PRO A CG 1 ATOM 2322 C CD . PRO A 1 303 ? 23.087 61.782 28.736 1.00 21.67 ? 303 PRO A CD 1 ATOM 2323 N N . ARG A 1 304 ? 23.008 58.599 32.006 1.00 24.08 ? 304 ARG A N 1 ATOM 2324 C CA . ARG A 1 304 ? 23.109 58.605 33.446 1.00 24.66 ? 304 ARG A CA 1 ATOM 2325 C C . ARG A 1 304 ? 24.312 57.779 33.849 1.00 22.61 ? 304 ARG A C 1 ATOM 2326 O O . ARG A 1 304 ? 24.545 56.701 33.280 1.00 21.99 ? 304 ARG A O 1 ATOM 2327 C CB . ARG A 1 304 ? 21.852 57.997 34.087 1.00 29.30 ? 304 ARG A CB 1 ATOM 2328 C CG . ARG A 1 304 ? 20.704 58.978 34.245 1.00 36.85 ? 304 ARG A CG 1 ATOM 2329 C CD . ARG A 1 304 ? 19.576 58.303 35.000 1.00 42.20 ? 304 ARG A CD 1 ATOM 2330 N NE . ARG A 1 304 ? 19.213 57.049 34.342 1.00 49.07 ? 304 ARG A NE 1 ATOM 2331 C CZ . ARG A 1 304 ? 18.354 56.156 34.822 1.00 51.75 ? 304 ARG A CZ 1 ATOM 2332 N NH1 . ARG A 1 304 ? 17.737 56.349 35.987 1.00 53.58 ? 304 ARG A NH1 1 ATOM 2333 N NH2 . ARG A 1 304 ? 18.112 55.057 34.125 1.00 54.58 ? 304 ARG A NH2 1 ATOM 2334 N N . THR A 1 305 ? 25.070 58.268 34.821 1.00 22.19 ? 305 THR A N 1 ATOM 2335 C CA . THR A 1 305 ? 26.233 57.569 35.313 1.00 22.87 ? 305 THR A CA 1 ATOM 2336 C C . THR A 1 305 ? 25.859 56.166 35.786 1.00 22.41 ? 305 THR A C 1 ATOM 2337 O O . THR A 1 305 ? 24.901 55.987 36.542 1.00 23.97 ? 305 THR A O 1 ATOM 2338 C CB . THR A 1 305 ? 26.875 58.390 36.461 1.00 23.36 ? 305 THR A CB 1 ATOM 2339 O OG1 . THR A 1 305 ? 27.367 59.611 35.890 1.00 26.92 ? 305 THR A OG1 1 ATOM 2340 C CG2 . THR A 1 305 ? 27.994 57.653 37.145 1.00 22.55 ? 305 THR A CG2 1 ATOM 2341 N N . ILE A 1 306 ? 26.590 55.165 35.331 1.00 19.45 ? 306 ILE A N 1 ATOM 2342 C CA . ILE A 1 306 ? 26.292 53.782 35.702 1.00 20.14 ? 306 ILE A CA 1 ATOM 2343 C C . ILE A 1 306 ? 26.738 53.558 37.146 1.00 20.24 ? 306 ILE A C 1 ATOM 2344 O O . ILE A 1 306 ? 27.851 53.920 37.560 1.00 21.50 ? 306 ILE A O 1 ATOM 2345 C CB . ILE A 1 306 ? 27.031 52.788 34.756 1.00 20.61 ? 306 ILE A CB 1 ATOM 2346 C CG1 . ILE A 1 306 ? 26.679 53.081 33.289 1.00 18.68 ? 306 ILE A CG1 1 ATOM 2347 C CG2 . ILE A 1 306 ? 26.698 51.308 35.144 1.00 19.50 ? 306 ILE A CG2 1 ATOM 2348 C CD1 . ILE A 1 306 ? 25.226 53.067 32.954 1.00 19.46 ? 306 ILE A CD1 1 ATOM 2349 N N . SER A 1 307 ? 25.834 52.946 37.918 1.00 22.06 ? 307 SER A N 1 ATOM 2350 C CA . SER A 1 307 ? 26.077 52.632 39.326 1.00 23.33 ? 307 SER A CA 1 ATOM 2351 C C . SER A 1 307 ? 25.573 51.231 39.608 1.00 23.85 ? 307 SER A C 1 ATOM 2352 O O . SER A 1 307 ? 24.903 50.622 38.784 1.00 22.34 ? 307 SER A O 1 ATOM 2353 C CB . SER A 1 307 ? 25.260 53.570 40.214 1.00 22.99 ? 307 SER A CB 1 ATOM 2354 O OG . SER A 1 307 ? 23.869 53.363 40.018 1.00 21.91 ? 307 SER A OG 1 ATOM 2355 N N . ASP A 1 308 ? 25.847 50.737 40.800 1.00 25.36 ? 308 ASP A N 1 ATOM 2356 C CA . ASP A 1 308 ? 25.335 49.416 41.140 1.00 27.53 ? 308 ASP A CA 1 ATOM 2357 C C . ASP A 1 308 ? 23.801 49.359 41.190 1.00 26.78 ? 308 ASP A C 1 ATOM 2358 O O . ASP A 1 308 ? 23.240 48.300 40.920 1.00 25.03 ? 308 ASP A O 1 ATOM 2359 C CB . ASP A 1 308 ? 25.931 48.929 42.461 1.00 31.64 ? 308 ASP A CB 1 ATOM 2360 C CG . ASP A 1 308 ? 27.424 48.672 42.363 1.00 35.50 ? 308 ASP A CG 1 ATOM 2361 O OD1 . ASP A 1 308 ? 27.953 48.568 41.233 1.00 39.50 ? 308 ASP A OD1 1 ATOM 2362 O OD2 . ASP A 1 308 ? 28.089 48.551 43.409 1.00 38.87 ? 308 ASP A OD2 1 ATOM 2363 N N . GLN A 1 309 ? 23.126 50.468 41.480 1.00 25.45 ? 309 GLN A N 1 ATOM 2364 C CA . GLN A 1 309 ? 21.652 50.507 41.543 1.00 26.85 ? 309 GLN A CA 1 ATOM 2365 C C . GLN A 1 309 ? 20.961 50.645 40.200 1.00 27.42 ? 309 GLN A C 1 ATOM 2366 O O . GLN A 1 309 ? 19.732 50.465 40.088 1.00 25.33 ? 309 GLN A O 1 ATOM 2367 C CB . GLN A 1 309 ? 21.133 51.658 42.435 1.00 25.21 ? 309 GLN A CB 1 ATOM 2368 C CG . GLN A 1 309 ? 21.582 51.584 43.888 1.00 29.97 ? 309 GLN A CG 1 ATOM 2369 C CD . GLN A 1 309 ? 23.084 51.747 44.022 1.00 31.11 ? 309 GLN A CD 1 ATOM 2370 O OE1 . GLN A 1 309 ? 23.662 52.702 43.476 1.00 32.93 ? 309 GLN A OE1 1 ATOM 2371 N NE2 . GLN A 1 309 ? 23.732 50.823 44.746 1.00 31.56 ? 309 GLN A NE2 1 ATOM 2372 N N . ASN A 1 310 ? 21.703 51.013 39.159 1.00 23.77 ? 310 ASN A N 1 ATOM 2373 C CA . ASN A 1 310 ? 21.007 51.130 37.895 1.00 22.17 ? 310 ASN A CA 1 ATOM 2374 C C . ASN A 1 310 ? 21.685 50.279 36.830 1.00 20.88 ? 310 ASN A C 1 ATOM 2375 O O . ASN A 1 310 ? 21.143 50.189 35.754 1.00 20.29 ? 310 ASN A O 1 ATOM 2376 C CB . ASN A 1 310 ? 20.933 52.596 37.414 1.00 23.19 ? 310 ASN A CB 1 ATOM 2377 C CG . ASN A 1 310 ? 22.307 53.190 37.052 1.00 22.24 ? 310 ASN A CG 1 ATOM 2378 O OD1 . ASN A 1 310 ? 23.280 52.469 36.800 1.00 22.35 ? 310 ASN A OD1 1 ATOM 2379 N ND2 . ASN A 1 310 ? 22.364 54.513 37.000 1.00 24.16 ? 310 ASN A ND2 1 ATOM 2380 N N . VAL A 1 311 ? 22.797 49.630 37.155 1.00 19.67 ? 311 VAL A N 1 ATOM 2381 C CA . VAL A 1 311 ? 23.529 48.889 36.074 1.00 18.92 ? 311 VAL A CA 1 ATOM 2382 C C . VAL A 1 311 ? 22.687 47.766 35.479 1.00 21.85 ? 311 VAL A C 1 ATOM 2383 O O . VAL A 1 311 ? 22.774 47.492 34.272 1.00 21.12 ? 311 VAL A O 1 ATOM 2384 C CB . VAL A 1 311 ? 24.901 48.345 36.548 1.00 20.00 ? 311 VAL A CB 1 ATOM 2385 C CG1 . VAL A 1 311 ? 24.737 47.252 37.569 1.00 20.40 ? 311 VAL A CG1 1 ATOM 2386 C CG2 . VAL A 1 311 ? 25.733 47.825 35.311 1.00 19.40 ? 311 VAL A CG2 1 ATOM 2387 N N . ALA A 1 312 ? 21.829 47.129 36.270 1.00 19.55 ? 312 ALA A N 1 ATOM 2388 C CA . ALA A 1 312 ? 21.038 46.058 35.679 1.00 20.78 ? 312 ALA A CA 1 ATOM 2389 C C . ALA A 1 312 ? 20.028 46.615 34.698 1.00 23.26 ? 312 ALA A C 1 ATOM 2390 O O . ALA A 1 312 ? 19.864 46.053 33.611 1.00 22.41 ? 312 ALA A O 1 ATOM 2391 C CB . ALA A 1 312 ? 20.323 45.209 36.797 1.00 21.71 ? 312 ALA A CB 1 ATOM 2392 N N . ALA A 1 313 ? 19.355 47.712 35.026 1.00 19.83 ? 313 ALA A N 1 ATOM 2393 C CA . ALA A 1 313 ? 18.371 48.292 34.127 1.00 21.34 ? 313 ALA A CA 1 ATOM 2394 C C . ALA A 1 313 ? 19.041 48.900 32.898 1.00 22.01 ? 313 ALA A C 1 ATOM 2395 O O . ALA A 1 313 ? 18.524 48.779 31.793 1.00 21.85 ? 313 ALA A O 1 ATOM 2396 C CB . ALA A 1 313 ? 17.517 49.365 34.865 1.00 22.64 ? 313 ALA A CB 1 ATOM 2397 N N . ARG A 1 314 ? 20.149 49.590 33.106 1.00 22.34 ? 314 ARG A N 1 ATOM 2398 C CA . ARG A 1 314 ? 20.877 50.195 31.976 1.00 22.11 ? 314 ARG A CA 1 ATOM 2399 C C . ARG A 1 314 ? 21.384 49.089 31.050 1.00 21.36 ? 314 ARG A C 1 ATOM 2400 O O . ARG A 1 314 ? 21.302 49.245 29.815 1.00 20.26 ? 314 ARG A O 1 ATOM 2401 C CB . ARG A 1 314 ? 22.060 51.017 32.487 1.00 19.98 ? 314 ARG A CB 1 ATOM 2402 C CG . ARG A 1 314 ? 21.669 52.178 33.376 1.00 22.79 ? 314 ARG A CG 1 ATOM 2403 C CD . ARG A 1 314 ? 21.394 53.411 32.589 1.00 25.58 ? 314 ARG A CD 1 ATOM 2404 N NE . ARG A 1 314 ? 20.035 53.436 32.102 1.00 27.75 ? 314 ARG A NE 1 ATOM 2405 C CZ . ARG A 1 314 ? 19.552 54.322 31.245 1.00 28.07 ? 314 ARG A CZ 1 ATOM 2406 N NH1 . ARG A 1 314 ? 20.336 55.279 30.737 1.00 29.80 ? 314 ARG A NH1 1 ATOM 2407 N NH2 . ARG A 1 314 ? 18.256 54.309 30.945 1.00 28.79 ? 314 ARG A NH2 1 ATOM 2408 N N . SER A 1 315 ? 21.888 48.000 31.626 1.00 20.87 ? 315 SER A N 1 ATOM 2409 C CA . SER A 1 315 ? 22.378 46.856 30.810 1.00 20.81 ? 315 SER A CA 1 ATOM 2410 C C . SER A 1 315 ? 21.244 46.226 30.053 1.00 23.32 ? 315 SER A C 1 ATOM 2411 O O . SER A 1 315 ? 21.398 45.806 28.896 1.00 22.64 ? 315 SER A O 1 ATOM 2412 C CB . SER A 1 315 ? 23.018 45.795 31.678 1.00 19.34 ? 315 SER A CB 1 ATOM 2413 O OG . SER A 1 315 ? 24.211 46.280 32.236 1.00 21.08 ? 315 SER A OG 1 ATOM 2414 N N . ASP A 1 316 ? 20.083 46.112 30.684 1.00 22.55 ? 316 ASP A N 1 ATOM 2415 C CA . ASP A 1 316 ? 18.952 45.533 29.981 1.00 25.29 ? 316 ASP A CA 1 ATOM 2416 C C . ASP A 1 316 ? 18.589 46.382 28.743 1.00 24.00 ? 316 ASP A C 1 ATOM 2417 O O . ASP A 1 316 ? 18.281 45.837 27.659 1.00 22.34 ? 316 ASP A O 1 ATOM 2418 C CB . ASP A 1 316 ? 17.742 45.434 30.920 1.00 27.61 ? 316 ASP A CB 1 ATOM 2419 C CG . ASP A 1 316 ? 16.785 44.360 30.482 1.00 33.97 ? 316 ASP A CG 1 ATOM 2420 O OD1 . ASP A 1 316 ? 17.294 43.258 30.134 1.00 34.29 ? 316 ASP A OD1 1 ATOM 2421 O OD2 . ASP A 1 316 ? 15.556 44.617 30.469 1.00 36.15 ? 316 ASP A OD2 1 ATOM 2422 N N . LEU A 1 317 ? 18.629 47.707 28.872 1.00 21.77 ? 317 LEU A N 1 ATOM 2423 C CA . LEU A 1 317 ? 18.295 48.572 27.738 1.00 22.09 ? 317 LEU A CA 1 ATOM 2424 C C . LEU A 1 317 ? 19.346 48.458 26.641 1.00 18.87 ? 317 LEU A C 1 ATOM 2425 O O . LEU A 1 317 ? 19.001 48.347 25.465 1.00 18.53 ? 317 LEU A O 1 ATOM 2426 C CB . LEU A 1 317 ? 18.209 50.051 28.155 1.00 24.53 ? 317 LEU A CB 1 ATOM 2427 C CG . LEU A 1 317 ? 16.848 50.597 28.573 1.00 28.63 ? 317 LEU A CG 1 ATOM 2428 C CD1 . LEU A 1 317 ? 17.093 51.910 29.326 1.00 29.59 ? 317 LEU A CD1 1 ATOM 2429 C CD2 . LEU A 1 317 ? 15.933 50.810 27.360 1.00 27.94 ? 317 LEU A CD2 1 ATOM 2430 N N . LEU A 1 318 ? 20.602 48.461 27.051 1.00 17.95 ? 318 LEU A N 1 ATOM 2431 C CA . LEU A 1 318 ? 21.717 48.432 26.071 1.00 17.35 ? 318 LEU A CA 1 ATOM 2432 C C . LEU A 1 318 ? 21.818 47.109 25.367 1.00 17.95 ? 318 LEU A C 1 ATOM 2433 O O . LEU A 1 318 ? 21.971 47.058 24.124 1.00 17.79 ? 318 LEU A O 1 ATOM 2434 C CB . LEU A 1 318 ? 23.032 48.761 26.764 1.00 16.56 ? 318 LEU A CB 1 ATOM 2435 C CG . LEU A 1 318 ? 24.281 48.845 25.846 1.00 17.59 ? 318 LEU A CG 1 ATOM 2436 C CD1 . LEU A 1 318 ? 24.050 49.944 24.789 1.00 18.99 ? 318 LEU A CD1 1 ATOM 2437 C CD2 . LEU A 1 318 ? 25.537 49.126 26.684 1.00 18.03 ? 318 LEU A CD2 1 ATOM 2438 N N . VAL A 1 319 ? 21.747 46.017 26.108 1.00 17.08 ? 319 VAL A N 1 ATOM 2439 C CA . VAL A 1 319 ? 21.862 44.694 25.479 1.00 16.78 ? 319 VAL A CA 1 ATOM 2440 C C . VAL A 1 319 ? 20.694 44.485 24.503 1.00 17.66 ? 319 VAL A C 1 ATOM 2441 O O . VAL A 1 319 ? 20.852 43.841 23.462 1.00 17.29 ? 319 VAL A O 1 ATOM 2442 C CB . VAL A 1 319 ? 21.889 43.543 26.525 1.00 17.06 ? 319 VAL A CB 1 ATOM 2443 C CG1 . VAL A 1 319 ? 21.737 42.193 25.795 1.00 19.57 ? 319 VAL A CG1 1 ATOM 2444 C CG2 . VAL A 1 319 ? 23.182 43.541 27.304 1.00 18.79 ? 319 VAL A CG2 1 ATOM 2445 N N . ASP A 1 320 ? 19.523 45.019 24.823 1.00 18.36 ? 320 ASP A N 1 ATOM 2446 C CA . ASP A 1 320 ? 18.380 44.906 23.912 1.00 17.90 ? 320 ASP A CA 1 ATOM 2447 C C . ASP A 1 320 ? 18.710 45.633 22.584 1.00 17.70 ? 320 ASP A C 1 ATOM 2448 O O . ASP A 1 320 ? 18.378 45.108 21.504 1.00 18.23 ? 320 ASP A O 1 ATOM 2449 C CB . ASP A 1 320 ? 17.111 45.473 24.593 1.00 21.55 ? 320 ASP A CB 1 ATOM 2450 C CG . ASP A 1 320 ? 15.924 45.531 23.672 1.00 19.12 ? 320 ASP A CG 1 ATOM 2451 O OD1 . ASP A 1 320 ? 15.421 44.446 23.291 1.00 23.33 ? 320 ASP A OD1 1 ATOM 2452 O OD2 . ASP A 1 320 ? 15.448 46.623 23.315 1.00 21.51 ? 320 ASP A OD2 1 ATOM 2453 N N . GLN A 1 321 ? 19.329 46.820 22.658 1.00 16.47 ? 321 GLN A N 1 ATOM 2454 C CA . GLN A 1 321 ? 19.713 47.525 21.422 1.00 15.61 ? 321 GLN A CA 1 ATOM 2455 C C . GLN A 1 321 ? 20.726 46.661 20.640 1.00 14.57 ? 321 GLN A C 1 ATOM 2456 O O . GLN A 1 321 ? 20.591 46.539 19.429 1.00 16.11 ? 321 GLN A O 1 ATOM 2457 C CB . GLN A 1 321 ? 20.364 48.873 21.771 1.00 14.40 ? 321 GLN A CB 1 ATOM 2458 C CG . GLN A 1 321 ? 19.365 49.934 22.209 1.00 17.11 ? 321 GLN A CG 1 ATOM 2459 C CD . GLN A 1 321 ? 18.281 50.123 21.144 1.00 19.00 ? 321 GLN A CD 1 ATOM 2460 O OE1 . GLN A 1 321 ? 18.571 50.528 20.033 1.00 18.92 ? 321 GLN A OE1 1 ATOM 2461 N NE2 . GLN A 1 321 ? 17.014 49.831 21.491 1.00 19.48 ? 321 GLN A NE2 1 ATOM 2462 N N . TRP A 1 322 ? 21.748 46.138 21.315 1.00 15.01 ? 322 TRP A N 1 ATOM 2463 C CA . TRP A 1 322 ? 22.746 45.287 20.657 1.00 14.60 ? 322 TRP A CA 1 ATOM 2464 C C . TRP A 1 322 ? 22.113 44.081 19.970 1.00 15.97 ? 322 TRP A C 1 ATOM 2465 O O . TRP A 1 322 ? 22.462 43.744 18.822 1.00 16.51 ? 322 TRP A O 1 ATOM 2466 C CB . TRP A 1 322 ? 23.770 44.794 21.667 1.00 14.59 ? 322 TRP A CB 1 ATOM 2467 C CG . TRP A 1 322 ? 24.690 45.862 22.216 1.00 16.22 ? 322 TRP A CG 1 ATOM 2468 C CD1 . TRP A 1 322 ? 24.879 47.157 21.754 1.00 15.61 ? 322 TRP A CD1 1 ATOM 2469 C CD2 . TRP A 1 322 ? 25.574 45.702 23.311 1.00 15.30 ? 322 TRP A CD2 1 ATOM 2470 N NE1 . TRP A 1 322 ? 25.844 47.796 22.520 1.00 16.90 ? 322 TRP A NE1 1 ATOM 2471 C CE2 . TRP A 1 322 ? 26.282 46.926 23.477 1.00 15.00 ? 322 TRP A CE2 1 ATOM 2472 C CE3 . TRP A 1 322 ? 25.850 44.638 24.180 1.00 17.33 ? 322 TRP A CE3 1 ATOM 2473 C CZ2 . TRP A 1 322 ? 27.245 47.112 24.489 1.00 16.94 ? 322 TRP A CZ2 1 ATOM 2474 C CZ3 . TRP A 1 322 ? 26.812 44.813 25.182 1.00 15.04 ? 322 TRP A CZ3 1 ATOM 2475 C CH2 . TRP A 1 322 ? 27.495 46.037 25.331 1.00 17.77 ? 322 TRP A CH2 1 ATOM 2476 N N . LYS A 1 323 ? 21.193 43.418 20.664 1.00 16.01 ? 323 LYS A N 1 ATOM 2477 C CA . LYS A 1 323 ? 20.581 42.221 20.056 1.00 17.28 ? 323 LYS A CA 1 ATOM 2478 C C . LYS A 1 323 ? 19.734 42.559 18.856 1.00 16.87 ? 323 LYS A C 1 ATOM 2479 O O . LYS A 1 323 ? 19.639 41.788 17.908 1.00 16.77 ? 323 LYS A O 1 ATOM 2480 C CB . LYS A 1 323 ? 19.794 41.401 21.116 1.00 18.69 ? 323 LYS A CB 1 ATOM 2481 C CG . LYS A 1 323 ? 20.778 40.606 21.997 1.00 17.62 ? 323 LYS A CG 1 ATOM 2482 C CD . LYS A 1 323 ? 20.096 39.784 23.085 1.00 18.49 ? 323 LYS A CD 1 ATOM 2483 C CE . LYS A 1 323 ? 21.107 38.880 23.733 1.00 20.92 ? 323 LYS A CE 1 ATOM 2484 N NZ . LYS A 1 323 ? 20.429 38.109 24.798 1.00 26.42 ? 323 LYS A NZ 1 ATOM 2485 N N . LYS A 1 324 ? 19.122 43.716 18.858 1.00 15.89 ? 324 LYS A N 1 ATOM 2486 C CA . LYS A 1 324 ? 18.358 44.179 17.693 1.00 16.82 ? 324 LYS A CA 1 ATOM 2487 C C . LYS A 1 324 ? 19.344 44.466 16.543 1.00 15.60 ? 324 LYS A C 1 ATOM 2488 O O . LYS A 1 324 ? 19.103 44.079 15.413 1.00 16.36 ? 324 LYS A O 1 ATOM 2489 C CB . LYS A 1 324 ? 17.566 45.449 18.037 1.00 16.10 ? 324 LYS A CB 1 ATOM 2490 C CG . LYS A 1 324 ? 16.324 45.093 18.838 1.00 16.72 ? 324 LYS A CG 1 ATOM 2491 C CD . LYS A 1 324 ? 15.696 46.323 19.449 1.00 19.13 ? 324 LYS A CD 1 ATOM 2492 C CE . LYS A 1 324 ? 14.395 45.885 20.175 1.00 21.53 ? 324 LYS A CE 1 ATOM 2493 N NZ . LYS A 1 324 ? 13.795 47.009 20.940 1.00 22.54 ? 324 LYS A NZ 1 ATOM 2494 N N . LYS A 1 325 ? 20.454 45.156 16.818 1.00 15.10 ? 325 LYS A N 1 ATOM 2495 C CA . LYS A 1 325 ? 21.413 45.430 15.737 1.00 13.30 ? 325 LYS A CA 1 ATOM 2496 C C . LYS A 1 325 ? 21.959 44.116 15.202 1.00 13.86 ? 325 LYS A C 1 ATOM 2497 O O . LYS A 1 325 ? 22.169 43.962 13.981 1.00 13.83 ? 325 LYS A O 1 ATOM 2498 C CB . LYS A 1 325 ? 22.557 46.302 16.270 1.00 12.51 ? 325 LYS A CB 1 ATOM 2499 C CG . LYS A 1 325 ? 23.443 46.902 15.144 1.00 14.09 ? 325 LYS A CG 1 ATOM 2500 C CD . LYS A 1 325 ? 24.561 47.779 15.730 1.00 14.28 ? 325 LYS A CD 1 ATOM 2501 C CE . LYS A 1 325 ? 25.349 48.482 14.581 1.00 13.64 ? 325 LYS A CE 1 ATOM 2502 N NZ . LYS A 1 325 ? 26.541 49.148 15.192 1.00 16.17 ? 325 LYS A NZ 1 ATOM 2503 N N . ALA A 1 326 ? 22.214 43.157 16.085 1.00 15.08 ? 326 ALA A N 1 ATOM 2504 C CA . ALA A 1 326 ? 22.753 41.857 15.666 1.00 16.07 ? 326 ALA A CA 1 ATOM 2505 C C . ALA A 1 326 ? 21.814 41.103 14.725 1.00 16.10 ? 326 ALA A C 1 ATOM 2506 O O . ALA A 1 326 ? 22.278 40.250 13.955 1.00 15.58 ? 326 ALA A O 1 ATOM 2507 C CB . ALA A 1 326 ? 23.084 41.002 16.888 1.00 15.89 ? 326 ALA A CB 1 ATOM 2508 N N . GLU A 1 327 ? 20.520 41.403 14.783 1.00 16.90 ? 327 GLU A N 1 ATOM 2509 C CA . GLU A 1 327 ? 19.569 40.759 13.876 1.00 17.72 ? 327 GLU A CA 1 ATOM 2510 C C . GLU A 1 327 ? 19.818 41.102 12.419 1.00 19.56 ? 327 GLU A C 1 ATOM 2511 O O . GLU A 1 327 ? 19.368 40.384 11.530 1.00 19.67 ? 327 GLU A O 1 ATOM 2512 C CB . GLU A 1 327 ? 18.129 41.172 14.195 1.00 20.92 ? 327 GLU A CB 1 ATOM 2513 C CG . GLU A 1 327 ? 17.508 40.395 15.289 1.00 25.04 ? 327 GLU A CG 1 ATOM 2514 C CD . GLU A 1 327 ? 17.540 38.885 15.033 1.00 21.21 ? 327 GLU A CD 1 ATOM 2515 O OE1 . GLU A 1 327 ? 16.889 38.365 14.083 1.00 26.56 ? 327 GLU A OE1 1 ATOM 2516 O OE2 . GLU A 1 327 ? 18.236 38.217 15.803 1.00 23.82 ? 327 GLU A OE2 1 ATOM 2517 N N . LEU A 1 328 ? 20.521 42.209 12.169 1.00 15.89 ? 328 LEU A N 1 ATOM 2518 C CA . LEU A 1 328 ? 20.759 42.654 10.791 1.00 14.03 ? 328 LEU A CA 1 ATOM 2519 C C . LEU A 1 328 ? 21.965 42.003 10.146 1.00 15.87 ? 328 LEU A C 1 ATOM 2520 O O . LEU A 1 328 ? 22.234 42.264 8.976 1.00 16.50 ? 328 LEU A O 1 ATOM 2521 C CB . LEU A 1 328 ? 20.962 44.174 10.793 1.00 14.18 ? 328 LEU A CB 1 ATOM 2522 C CG . LEU A 1 328 ? 19.855 44.965 11.509 1.00 14.73 ? 328 LEU A CG 1 ATOM 2523 C CD1 . LEU A 1 328 ? 20.082 46.483 11.289 1.00 16.19 ? 328 LEU A CD1 1 ATOM 2524 C CD2 . LEU A 1 328 ? 18.446 44.590 10.975 1.00 16.99 ? 328 LEU A CD2 1 ATOM 2525 N N . TYR A 1 329 ? 22.701 41.193 10.902 1.00 14.95 ? 329 TYR A N 1 ATOM 2526 C CA . TYR A 1 329 ? 23.918 40.564 10.435 1.00 13.91 ? 329 TYR A CA 1 ATOM 2527 C C . TYR A 1 329 ? 23.888 39.067 10.628 1.00 16.05 ? 329 TYR A C 1 ATOM 2528 O O . TYR A 1 329 ? 23.061 38.541 11.384 1.00 18.57 ? 329 TYR A O 1 ATOM 2529 C CB . TYR A 1 329 ? 25.160 41.164 11.136 1.00 15.88 ? 329 TYR A CB 1 ATOM 2530 C CG . TYR A 1 329 ? 25.374 42.638 10.807 1.00 14.39 ? 329 TYR A CG 1 ATOM 2531 C CD1 . TYR A 1 329 ? 26.093 42.999 9.698 1.00 15.23 ? 329 TYR A CD1 1 ATOM 2532 C CD2 . TYR A 1 329 ? 24.789 43.647 11.588 1.00 14.03 ? 329 TYR A CD2 1 ATOM 2533 C CE1 . TYR A 1 329 ? 26.223 44.350 9.342 1.00 13.74 ? 329 TYR A CE1 1 ATOM 2534 C CE2 . TYR A 1 329 ? 24.922 44.986 11.269 1.00 15.12 ? 329 TYR A CE2 1 ATOM 2535 C CZ . TYR A 1 329 ? 25.641 45.332 10.120 1.00 13.75 ? 329 TYR A CZ 1 ATOM 2536 O OH . TYR A 1 329 ? 25.723 46.674 9.760 1.00 15.97 ? 329 TYR A OH 1 ATOM 2537 N N . ARG A 1 330 ? 24.800 38.385 9.969 1.00 15.49 ? 330 ARG A N 1 ATOM 2538 C CA . ARG A 1 330 ? 24.788 36.924 9.972 1.00 15.70 ? 330 ARG A CA 1 ATOM 2539 C C . ARG A 1 330 ? 25.563 36.162 11.011 1.00 17.60 ? 330 ARG A C 1 ATOM 2540 O O . ARG A 1 330 ? 25.338 34.954 11.165 1.00 20.81 ? 330 ARG A O 1 ATOM 2541 C CB . ARG A 1 330 ? 25.185 36.420 8.569 1.00 16.19 ? 330 ARG A CB 1 ATOM 2542 C CG . ARG A 1 330 ? 24.211 36.859 7.494 1.00 17.09 ? 330 ARG A CG 1 ATOM 2543 C CD . ARG A 1 330 ? 24.594 36.321 6.098 1.00 17.95 ? 330 ARG A CD 1 ATOM 2544 N NE . ARG A 1 330 ? 23.600 36.858 5.186 1.00 18.84 ? 330 ARG A NE 1 ATOM 2545 C CZ . ARG A 1 330 ? 23.256 36.343 4.010 1.00 23.89 ? 330 ARG A CZ 1 ATOM 2546 N NH1 . ARG A 1 330 ? 23.839 35.242 3.546 1.00 23.95 ? 330 ARG A NH1 1 ATOM 2547 N NH2 . ARG A 1 330 ? 22.301 36.939 3.299 1.00 21.92 ? 330 ARG A NH2 1 ATOM 2548 N N . THR A 1 331 ? 26.489 36.808 11.708 1.00 16.28 ? 331 THR A N 1 ATOM 2549 C CA . THR A 1 331 ? 27.268 36.068 12.706 1.00 14.82 ? 331 THR A CA 1 ATOM 2550 C C . THR A 1 331 ? 26.872 36.498 14.098 1.00 14.86 ? 331 THR A C 1 ATOM 2551 O O . THR A 1 331 ? 26.036 37.389 14.249 1.00 18.46 ? 331 THR A O 1 ATOM 2552 C CB . THR A 1 331 ? 28.807 36.299 12.563 1.00 17.03 ? 331 THR A CB 1 ATOM 2553 O OG1 . THR A 1 331 ? 29.157 37.606 13.031 1.00 15.50 ? 331 THR A OG1 1 ATOM 2554 C CG2 . THR A 1 331 ? 29.266 36.129 11.066 1.00 17.35 ? 331 THR A CG2 1 ATOM 2555 N N . ASN A 1 332 ? 27.483 35.855 15.093 1.00 16.72 ? 332 ASN A N 1 ATOM 2556 C CA . ASN A 1 332 ? 27.264 36.215 16.495 1.00 17.69 ? 332 ASN A CA 1 ATOM 2557 C C . ASN A 1 332 ? 28.350 37.157 16.991 1.00 16.87 ? 332 ASN A C 1 ATOM 2558 O O . ASN A 1 332 ? 28.617 37.243 18.200 1.00 18.35 ? 332 ASN A O 1 ATOM 2559 C CB . ASN A 1 332 ? 27.256 34.959 17.381 1.00 19.05 ? 332 ASN A CB 1 ATOM 2560 C CG . ASN A 1 332 ? 28.630 34.287 17.507 1.00 24.76 ? 332 ASN A CG 1 ATOM 2561 O OD1 . ASN A 1 332 ? 29.445 34.266 16.583 1.00 24.79 ? 332 ASN A OD1 1 ATOM 2562 N ND2 . ASN A 1 332 ? 28.870 33.685 18.677 1.00 27.86 ? 332 ASN A ND2 1 ATOM 2563 N N . VAL A 1 333 ? 28.952 37.908 16.070 1.00 15.66 ? 333 VAL A N 1 ATOM 2564 C CA . VAL A 1 333 ? 30.001 38.859 16.399 1.00 14.68 ? 333 VAL A CA 1 ATOM 2565 C C . VAL A 1 333 ? 29.438 40.215 15.971 1.00 14.89 ? 333 VAL A C 1 ATOM 2566 O O . VAL A 1 333 ? 29.127 40.402 14.796 1.00 16.33 ? 333 VAL A O 1 ATOM 2567 C CB . VAL A 1 333 ? 31.289 38.544 15.611 1.00 14.41 ? 333 VAL A CB 1 ATOM 2568 C CG1 . VAL A 1 333 ? 32.380 39.556 15.977 1.00 17.65 ? 333 VAL A CG1 1 ATOM 2569 C CG2 . VAL A 1 333 ? 31.740 37.103 15.916 1.00 17.95 ? 333 VAL A CG2 1 ATOM 2570 N N . LEU A 1 334 ? 29.346 41.165 16.905 1.00 14.01 ? 334 LEU A N 1 ATOM 2571 C CA . LEU A 1 334 ? 28.731 42.459 16.658 1.00 12.84 ? 334 LEU A CA 1 ATOM 2572 C C . LEU A 1 334 ? 29.694 43.616 16.818 1.00 12.01 ? 334 LEU A C 1 ATOM 2573 O O . LEU A 1 334 ? 30.413 43.706 17.810 1.00 15.20 ? 334 LEU A O 1 ATOM 2574 C CB . LEU A 1 334 ? 27.586 42.671 17.657 1.00 13.46 ? 334 LEU A CB 1 ATOM 2575 C CG . LEU A 1 334 ? 26.736 43.928 17.466 1.00 13.91 ? 334 LEU A CG 1 ATOM 2576 C CD1 . LEU A 1 334 ? 25.958 43.804 16.145 1.00 15.48 ? 334 LEU A CD1 1 ATOM 2577 C CD2 . LEU A 1 334 ? 25.766 44.089 18.676 1.00 15.34 ? 334 LEU A CD2 1 ATOM 2578 N N . LEU A 1 335 ? 29.666 44.527 15.832 1.00 12.61 ? 335 LEU A N 1 ATOM 2579 C CA . LEU A 1 335 ? 30.536 45.699 15.855 1.00 12.77 ? 335 LEU A CA 1 ATOM 2580 C C . LEU A 1 335 ? 29.757 46.889 16.400 1.00 12.18 ? 335 LEU A C 1 ATOM 2581 O O . LEU A 1 335 ? 28.712 47.234 15.869 1.00 14.16 ? 335 LEU A O 1 ATOM 2582 C CB . LEU A 1 335 ? 31.001 46.027 14.427 1.00 12.74 ? 335 LEU A CB 1 ATOM 2583 C CG . LEU A 1 335 ? 31.848 47.303 14.304 1.00 11.84 ? 335 LEU A CG 1 ATOM 2584 C CD1 . LEU A 1 335 ? 33.168 47.173 15.067 1.00 15.97 ? 335 LEU A CD1 1 ATOM 2585 C CD2 . LEU A 1 335 ? 32.081 47.613 12.826 1.00 14.85 ? 335 LEU A CD2 1 ATOM 2586 N N . ILE A 1 336 ? 30.276 47.516 17.455 1.00 12.38 ? 336 ILE A N 1 ATOM 2587 C CA . ILE A 1 336 ? 29.659 48.699 18.017 1.00 13.57 ? 336 ILE A CA 1 ATOM 2588 C C . ILE A 1 336 ? 30.671 49.865 18.062 1.00 12.40 ? 336 ILE A C 1 ATOM 2589 O O . ILE A 1 336 ? 31.463 49.981 19.008 1.00 13.18 ? 336 ILE A O 1 ATOM 2590 C CB . ILE A 1 336 ? 29.124 48.461 19.448 1.00 15.90 ? 336 ILE A CB 1 ATOM 2591 C CG1 . ILE A 1 336 ? 28.089 47.326 19.456 1.00 13.52 ? 336 ILE A CG1 1 ATOM 2592 C CG2 . ILE A 1 336 ? 28.535 49.785 19.963 1.00 14.38 ? 336 ILE A CG2 1 ATOM 2593 C CD1 . ILE A 1 336 ? 26.824 47.647 18.682 1.00 14.37 ? 336 ILE A CD1 1 ATOM 2594 N N . PRO A 1 337 ? 30.706 50.704 17.024 1.00 13.48 ? 337 PRO A N 1 ATOM 2595 C CA . PRO A 1 337 ? 31.646 51.839 17.075 1.00 13.16 ? 337 PRO A CA 1 ATOM 2596 C C . PRO A 1 337 ? 31.227 52.752 18.243 1.00 14.10 ? 337 PRO A C 1 ATOM 2597 O O . PRO A 1 337 ? 30.033 52.879 18.550 1.00 15.02 ? 337 PRO A O 1 ATOM 2598 C CB . PRO A 1 337 ? 31.385 52.563 15.745 1.00 13.25 ? 337 PRO A CB 1 ATOM 2599 C CG . PRO A 1 337 ? 30.930 51.444 14.844 1.00 13.03 ? 337 PRO A CG 1 ATOM 2600 C CD . PRO A 1 337 ? 29.961 50.685 15.746 1.00 14.55 ? 337 PRO A CD 1 ATOM 2601 N N . LEU A 1 338 ? 32.213 53.391 18.880 1.00 12.36 ? 338 LEU A N 1 ATOM 2602 C CA . LEU A 1 338 ? 31.939 54.323 19.971 1.00 12.66 ? 338 LEU A CA 1 ATOM 2603 C C . LEU A 1 338 ? 32.750 55.600 19.745 1.00 12.65 ? 338 LEU A C 1 ATOM 2604 O O . LEU A 1 338 ? 33.923 55.689 20.147 1.00 13.63 ? 338 LEU A O 1 ATOM 2605 C CB . LEU A 1 338 ? 32.280 53.657 21.294 1.00 14.48 ? 338 LEU A CB 1 ATOM 2606 C CG . LEU A 1 338 ? 31.912 54.560 22.487 1.00 15.72 ? 338 LEU A CG 1 ATOM 2607 C CD1 . LEU A 1 338 ? 30.406 54.483 22.803 1.00 17.11 ? 338 LEU A CD1 1 ATOM 2608 C CD2 . LEU A 1 338 ? 32.716 54.087 23.690 1.00 17.73 ? 338 LEU A CD2 1 ATOM 2609 N N . GLY A 1 339 ? 32.109 56.563 19.066 1.00 12.87 ? 339 GLY A N 1 ATOM 2610 C CA . GLY A 1 339 ? 32.859 57.799 18.783 1.00 12.98 ? 339 GLY A CA 1 ATOM 2611 C C . GLY A 1 339 ? 32.056 58.788 17.981 1.00 13.14 ? 339 GLY A C 1 ATOM 2612 O O . GLY A 1 339 ? 30.884 58.549 17.688 1.00 14.55 ? 339 GLY A O 1 ATOM 2613 N N . ASP A 1 340 ? 32.715 59.908 17.623 1.00 12.80 ? 340 ASP A N 1 ATOM 2614 C CA . ASP A 1 340 ? 32.078 60.978 16.892 1.00 13.05 ? 340 ASP A CA 1 ATOM 2615 C C . ASP A 1 340 ? 33.208 61.930 16.485 1.00 11.88 ? 340 ASP A C 1 ATOM 2616 O O . ASP A 1 340 ? 34.396 61.632 16.698 1.00 12.32 ? 340 ASP A O 1 ATOM 2617 C CB . ASP A 1 340 ? 31.044 61.670 17.814 1.00 13.34 ? 340 ASP A CB 1 ATOM 2618 C CG . ASP A 1 340 ? 29.930 62.388 17.057 1.00 14.99 ? 340 ASP A CG 1 ATOM 2619 O OD1 . ASP A 1 340 ? 30.090 62.736 15.836 1.00 15.67 ? 340 ASP A OD1 1 ATOM 2620 O OD2 . ASP A 1 340 ? 28.897 62.647 17.729 1.00 16.76 ? 340 ASP A OD2 1 ATOM 2621 N N . ASP A 1 341 ? 32.825 63.080 15.970 1.00 13.19 ? 341 ASP A N 1 ATOM 2622 C CA . ASP A 1 341 ? 33.819 64.032 15.455 1.00 13.27 ? 341 ASP A CA 1 ATOM 2623 C C . ASP A 1 341 ? 34.696 64.563 16.581 1.00 14.73 ? 341 ASP A C 1 ATOM 2624 O O . ASP A 1 341 ? 34.191 65.054 17.614 1.00 15.15 ? 341 ASP A O 1 ATOM 2625 C CB . ASP A 1 341 ? 33.134 65.202 14.764 1.00 15.57 ? 341 ASP A CB 1 ATOM 2626 C CG . ASP A 1 341 ? 32.469 64.810 13.462 1.00 15.98 ? 341 ASP A CG 1 ATOM 2627 O OD1 . ASP A 1 341 ? 32.403 63.603 13.142 1.00 15.96 ? 341 ASP A OD1 1 ATOM 2628 O OD2 . ASP A 1 341 ? 32.019 65.746 12.756 1.00 17.85 ? 341 ASP A OD2 1 ATOM 2629 N N . PHE A 1 342 ? 35.997 64.476 16.372 1.00 12.47 ? 342 PHE A N 1 ATOM 2630 C CA . PHE A 1 342 ? 36.990 64.980 17.318 1.00 12.35 ? 342 PHE A CA 1 ATOM 2631 C C . PHE A 1 342 ? 36.721 64.591 18.781 1.00 13.57 ? 342 PHE A C 1 ATOM 2632 O O . PHE A 1 342 ? 36.960 65.374 19.712 1.00 16.61 ? 342 PHE A O 1 ATOM 2633 C CB . PHE A 1 342 ? 37.164 66.513 17.123 1.00 13.51 ? 342 PHE A CB 1 ATOM 2634 C CG . PHE A 1 342 ? 37.738 66.892 15.773 1.00 12.95 ? 342 PHE A CG 1 ATOM 2635 C CD1 . PHE A 1 342 ? 39.112 66.868 15.550 1.00 12.24 ? 342 PHE A CD1 1 ATOM 2636 C CD2 . PHE A 1 342 ? 36.885 67.292 14.707 1.00 12.75 ? 342 PHE A CD2 1 ATOM 2637 C CE1 . PHE A 1 342 ? 39.655 67.232 14.308 1.00 12.14 ? 342 PHE A CE1 1 ATOM 2638 C CE2 . PHE A 1 342 ? 37.433 67.654 13.478 1.00 14.71 ? 342 PHE A CE2 1 ATOM 2639 C CZ . PHE A 1 342 ? 38.799 67.621 13.287 1.00 13.50 ? 342 PHE A CZ 1 ATOM 2640 N N . ARG A 1 343 ? 36.332 63.334 18.949 1.00 13.93 ? 343 ARG A N 1 ATOM 2641 C CA . ARG A 1 343 ? 36.096 62.818 20.275 1.00 12.80 ? 343 ARG A CA 1 ATOM 2642 C C . ARG A 1 343 ? 37.380 62.360 20.942 1.00 15.89 ? 343 ARG A C 1 ATOM 2643 O O . ARG A 1 343 ? 38.462 62.271 20.337 1.00 14.13 ? 343 ARG A O 1 ATOM 2644 C CB . ARG A 1 343 ? 35.052 61.679 20.219 1.00 12.78 ? 343 ARG A CB 1 ATOM 2645 C CG . ARG A 1 343 ? 33.621 62.145 19.965 1.00 14.74 ? 343 ARG A CG 1 ATOM 2646 C CD . ARG A 1 343 ? 33.169 63.105 21.104 1.00 13.45 ? 343 ARG A CD 1 ATOM 2647 N NE . ARG A 1 343 ? 31.740 63.385 21.054 1.00 15.42 ? 343 ARG A NE 1 ATOM 2648 C CZ . ARG A 1 343 ? 30.791 62.684 21.692 1.00 15.65 ? 343 ARG A CZ 1 ATOM 2649 N NH1 . ARG A 1 343 ? 31.118 61.633 22.437 1.00 15.14 ? 343 ARG A NH1 1 ATOM 2650 N NH2 . ARG A 1 343 ? 29.525 63.093 21.614 1.00 15.63 ? 343 ARG A NH2 1 ATOM 2651 N N . PHE A 1 344 ? 37.254 62.081 22.231 1.00 15.03 ? 344 PHE A N 1 ATOM 2652 C CA . PHE A 1 344 ? 38.346 61.603 23.083 1.00 15.97 ? 344 PHE A CA 1 ATOM 2653 C C . PHE A 1 344 ? 39.461 62.634 23.207 1.00 16.18 ? 344 PHE A C 1 ATOM 2654 O O . PHE A 1 344 ? 40.631 62.345 23.072 1.00 18.02 ? 344 PHE A O 1 ATOM 2655 C CB . PHE A 1 344 ? 38.803 60.220 22.590 1.00 14.91 ? 344 PHE A CB 1 ATOM 2656 C CG . PHE A 1 344 ? 37.772 59.184 22.789 1.00 15.24 ? 344 PHE A CG 1 ATOM 2657 C CD1 . PHE A 1 344 ? 37.568 58.643 24.063 1.00 17.42 ? 344 PHE A CD1 1 ATOM 2658 C CD2 . PHE A 1 344 ? 36.952 58.784 21.763 1.00 16.01 ? 344 PHE A CD2 1 ATOM 2659 C CE1 . PHE A 1 344 ? 36.536 57.702 24.278 1.00 17.66 ? 344 PHE A CE1 1 ATOM 2660 C CE2 . PHE A 1 344 ? 35.929 57.862 21.967 1.00 17.17 ? 344 PHE A CE2 1 ATOM 2661 C CZ . PHE A 1 344 ? 35.724 57.320 23.235 1.00 18.07 ? 344 PHE A CZ 1 ATOM 2662 N N . LYS A 1 345 ? 39.044 63.863 23.481 1.00 16.75 ? 345 LYS A N 1 ATOM 2663 C CA . LYS A 1 345 ? 39.960 64.974 23.636 1.00 19.08 ? 345 LYS A CA 1 ATOM 2664 C C . LYS A 1 345 ? 40.309 65.091 25.134 1.00 20.42 ? 345 LYS A C 1 ATOM 2665 O O . LYS A 1 345 ? 41.380 64.695 25.561 1.00 25.47 ? 345 LYS A O 1 ATOM 2666 C CB . LYS A 1 345 ? 39.273 66.252 23.145 1.00 19.34 ? 345 LYS A CB 1 ATOM 2667 C CG . LYS A 1 345 ? 40.150 67.462 23.142 1.00 22.52 ? 345 LYS A CG 1 ATOM 2668 C CD . LYS A 1 345 ? 39.338 68.669 22.720 1.00 27.05 ? 345 LYS A CD 1 ATOM 2669 C CE . LYS A 1 345 ? 40.154 69.924 22.876 1.00 26.28 ? 345 LYS A CE 1 ATOM 2670 N NZ . LYS A 1 345 ? 39.391 71.089 22.323 1.00 29.10 ? 345 LYS A NZ 1 ATOM 2671 N N . GLN A 1 346 ? 39.345 65.539 25.920 1.00 20.98 ? 346 GLN A N 1 ATOM 2672 C CA . GLN A 1 346 ? 39.560 65.737 27.342 1.00 21.52 ? 346 GLN A CA 1 ATOM 2673 C C . GLN A 1 346 ? 39.867 64.477 28.145 1.00 19.65 ? 346 GLN A C 1 ATOM 2674 O O . GLN A 1 346 ? 39.275 63.418 27.906 1.00 18.49 ? 346 GLN A O 1 ATOM 2675 C CB . GLN A 1 346 ? 38.323 66.418 27.967 1.00 23.70 ? 346 GLN A CB 1 ATOM 2676 C CG . GLN A 1 346 ? 37.902 67.814 27.420 1.00 29.47 ? 346 GLN A CG 1 ATOM 2677 C CD . GLN A 1 346 ? 36.713 67.755 26.422 1.00 33.06 ? 346 GLN A CD 1 ATOM 2678 O OE1 . GLN A 1 346 ? 35.905 68.684 26.361 1.00 35.79 ? 346 GLN A OE1 1 ATOM 2679 N NE2 . GLN A 1 346 ? 36.620 66.673 25.636 1.00 26.10 ? 346 GLN A NE2 1 ATOM 2680 N N . ASN A 1 347 ? 40.738 64.587 29.150 1.00 19.97 ? 347 ASN A N 1 ATOM 2681 C CA . ASN A 1 347 ? 41.007 63.450 30.033 1.00 20.87 ? 347 ASN A CA 1 ATOM 2682 C C . ASN A 1 347 ? 39.706 63.015 30.726 1.00 19.03 ? 347 ASN A C 1 ATOM 2683 O O . ASN A 1 347 ? 39.427 61.823 30.848 1.00 19.61 ? 347 ASN A O 1 ATOM 2684 C CB . ASN A 1 347 ? 42.024 63.857 31.102 1.00 23.35 ? 347 ASN A CB 1 ATOM 2685 C CG . ASN A 1 347 ? 43.354 64.043 30.511 1.00 29.00 ? 347 ASN A CG 1 ATOM 2686 O OD1 . ASN A 1 347 ? 43.858 63.121 29.885 1.00 30.88 ? 347 ASN A OD1 1 ATOM 2687 N ND2 . ASN A 1 347 ? 43.945 65.242 30.658 1.00 32.54 ? 347 ASN A ND2 1 ATOM 2688 N N . THR A 1 348 ? 38.894 63.994 31.128 1.00 18.03 ? 348 THR A N 1 ATOM 2689 C CA . THR A 1 348 ? 37.625 63.698 31.767 1.00 19.36 ? 348 THR A CA 1 ATOM 2690 C C . THR A 1 348 ? 36.698 62.930 30.827 1.00 18.15 ? 348 THR A C 1 ATOM 2691 O O . THR A 1 348 ? 35.853 62.136 31.278 1.00 19.17 ? 348 THR A O 1 ATOM 2692 C CB . THR A 1 348 ? 36.901 64.992 32.243 1.00 20.11 ? 348 THR A CB 1 ATOM 2693 O OG1 . THR A 1 348 ? 36.760 65.911 31.154 1.00 24.28 ? 348 THR A OG1 1 ATOM 2694 C CG2 . THR A 1 348 ? 37.711 65.674 33.382 1.00 21.97 ? 348 THR A CG2 1 ATOM 2695 N N . GLU A 1 349 ? 36.845 63.160 29.504 1.00 16.22 ? 349 GLU A N 1 ATOM 2696 C CA . GLU A 1 349 ? 36.008 62.451 28.535 1.00 16.41 ? 349 GLU A CA 1 ATOM 2697 C C . GLU A 1 349 ? 36.470 60.995 28.416 1.00 16.04 ? 349 GLU A C 1 ATOM 2698 O O . GLU A 1 349 ? 35.647 60.088 28.364 1.00 15.04 ? 349 GLU A O 1 ATOM 2699 C CB . GLU A 1 349 ? 36.114 63.124 27.163 1.00 14.33 ? 349 GLU A CB 1 ATOM 2700 C CG . GLU A 1 349 ? 35.338 62.361 26.097 1.00 15.56 ? 349 GLU A CG 1 ATOM 2701 C CD . GLU A 1 349 ? 35.554 62.954 24.697 1.00 15.56 ? 349 GLU A CD 1 ATOM 2702 O OE1 . GLU A 1 349 ? 36.234 63.971 24.544 1.00 17.72 ? 349 GLU A OE1 1 ATOM 2703 O OE2 . GLU A 1 349 ? 34.991 62.379 23.765 1.00 16.30 ? 349 GLU A OE2 1 ATOM 2704 N N . TRP A 1 350 ? 37.783 60.774 28.331 1.00 16.03 ? 350 TRP A N 1 ATOM 2705 C CA . TRP A 1 350 ? 38.294 59.404 28.304 1.00 16.05 ? 350 TRP A CA 1 ATOM 2706 C C . TRP A 1 350 ? 37.746 58.643 29.522 1.00 16.39 ? 350 TRP A C 1 ATOM 2707 O O . TRP A 1 350 ? 37.237 57.529 29.392 1.00 17.34 ? 350 TRP A O 1 ATOM 2708 C CB . TRP A 1 350 ? 39.806 59.357 28.348 1.00 15.85 ? 350 TRP A CB 1 ATOM 2709 C CG . TRP A 1 350 ? 40.456 59.565 27.020 1.00 16.07 ? 350 TRP A CG 1 ATOM 2710 C CD1 . TRP A 1 350 ? 40.823 60.758 26.474 1.00 15.79 ? 350 TRP A CD1 1 ATOM 2711 C CD2 . TRP A 1 350 ? 40.742 58.555 26.049 1.00 15.30 ? 350 TRP A CD2 1 ATOM 2712 N NE1 . TRP A 1 350 ? 41.337 60.555 25.197 1.00 14.86 ? 350 TRP A NE1 1 ATOM 2713 C CE2 . TRP A 1 350 ? 41.284 59.219 24.910 1.00 15.05 ? 350 TRP A CE2 1 ATOM 2714 C CE3 . TRP A 1 350 ? 40.588 57.160 26.014 1.00 17.93 ? 350 TRP A CE3 1 ATOM 2715 C CZ2 . TRP A 1 350 ? 41.661 58.531 23.753 1.00 16.72 ? 350 TRP A CZ2 1 ATOM 2716 C CZ3 . TRP A 1 350 ? 40.982 56.479 24.833 1.00 18.13 ? 350 TRP A CZ3 1 ATOM 2717 C CH2 . TRP A 1 350 ? 41.501 57.175 23.732 1.00 18.39 ? 350 TRP A CH2 1 ATOM 2718 N N . ASP A 1 351 ? 37.842 59.261 30.699 1.00 18.11 ? 351 ASP A N 1 ATOM 2719 C CA . ASP A 1 351 ? 37.368 58.620 31.913 1.00 18.31 ? 351 ASP A CA 1 ATOM 2720 C C . ASP A 1 351 ? 35.888 58.348 31.914 1.00 16.52 ? 351 ASP A C 1 ATOM 2721 O O . ASP A 1 351 ? 35.467 57.235 32.247 1.00 16.76 ? 351 ASP A O 1 ATOM 2722 C CB . ASP A 1 351 ? 37.651 59.495 33.134 1.00 20.04 ? 351 ASP A CB 1 ATOM 2723 C CG . ASP A 1 351 ? 39.090 59.511 33.535 1.00 25.09 ? 351 ASP A CG 1 ATOM 2724 O OD1 . ASP A 1 351 ? 39.830 58.539 33.248 1.00 27.66 ? 351 ASP A OD1 1 ATOM 2725 O OD2 . ASP A 1 351 ? 39.489 60.496 34.204 1.00 29.04 ? 351 ASP A OD2 1 ATOM 2726 N N . VAL A 1 352 ? 35.091 59.341 31.533 1.00 16.35 ? 352 VAL A N 1 ATOM 2727 C CA . VAL A 1 352 ? 33.665 59.162 31.595 1.00 18.76 ? 352 VAL A CA 1 ATOM 2728 C C . VAL A 1 352 ? 33.184 58.045 30.661 1.00 19.48 ? 352 VAL A C 1 ATOM 2729 O O . VAL A 1 352 ? 32.293 57.272 31.003 1.00 19.68 ? 352 VAL A O 1 ATOM 2730 C CB . VAL A 1 352 ? 32.902 60.514 31.358 1.00 21.03 ? 352 VAL A CB 1 ATOM 2731 C CG1 . VAL A 1 352 ? 32.628 60.763 29.900 1.00 20.13 ? 352 VAL A CG1 1 ATOM 2732 C CG2 . VAL A 1 352 ? 31.597 60.519 32.162 1.00 24.58 ? 352 VAL A CG2 1 ATOM 2733 N N . GLN A 1 353 ? 33.795 57.918 29.485 1.00 16.27 ? 353 GLN A N 1 ATOM 2734 C CA . GLN A 1 353 ? 33.342 56.859 28.601 1.00 15.90 ? 353 GLN A CA 1 ATOM 2735 C C . GLN A 1 353 ? 33.881 55.515 29.099 1.00 16.03 ? 353 GLN A C 1 ATOM 2736 O O . GLN A 1 353 ? 33.113 54.545 29.228 1.00 16.91 ? 353 GLN A O 1 ATOM 2737 C CB . GLN A 1 353 ? 33.856 57.128 27.163 1.00 14.24 ? 353 GLN A CB 1 ATOM 2738 C CG . GLN A 1 353 ? 33.319 58.426 26.489 1.00 14.81 ? 353 GLN A CG 1 ATOM 2739 C CD . GLN A 1 353 ? 31.860 58.331 26.028 1.00 15.32 ? 353 GLN A CD 1 ATOM 2740 O OE1 . GLN A 1 353 ? 31.044 57.603 26.625 1.00 16.96 ? 353 GLN A OE1 1 ATOM 2741 N NE2 . GLN A 1 353 ? 31.503 59.067 24.989 1.00 15.13 ? 353 GLN A NE2 1 ATOM 2742 N N . ARG A 1 354 ? 35.175 55.446 29.401 1.00 15.64 ? 354 ARG A N 1 ATOM 2743 C CA . ARG A 1 354 ? 35.766 54.200 29.831 1.00 16.01 ? 354 ARG A CA 1 ATOM 2744 C C . ARG A 1 354 ? 35.163 53.605 31.102 1.00 17.22 ? 354 ARG A C 1 ATOM 2745 O O . ARG A 1 354 ? 34.837 52.431 31.119 1.00 17.20 ? 354 ARG A O 1 ATOM 2746 C CB . ARG A 1 354 ? 37.265 54.332 30.063 1.00 15.24 ? 354 ARG A CB 1 ATOM 2747 C CG . ARG A 1 354 ? 37.903 53.011 30.527 1.00 17.11 ? 354 ARG A CG 1 ATOM 2748 C CD . ARG A 1 354 ? 39.420 53.183 30.758 1.00 18.69 ? 354 ARG A CD 1 ATOM 2749 N NE . ARG A 1 354 ? 39.725 54.229 31.738 1.00 20.93 ? 354 ARG A NE 1 ATOM 2750 C CZ . ARG A 1 354 ? 39.549 54.129 33.058 1.00 21.74 ? 354 ARG A CZ 1 ATOM 2751 N NH1 . ARG A 1 354 ? 39.067 53.023 33.604 1.00 21.07 ? 354 ARG A NH1 1 ATOM 2752 N NH2 . ARG A 1 354 ? 39.878 55.150 33.837 1.00 23.45 ? 354 ARG A NH2 1 ATOM 2753 N N . VAL A 1 355 ? 35.047 54.412 32.157 1.00 18.08 ? 355 VAL A N 1 ATOM 2754 C CA . VAL A 1 355 ? 34.554 53.883 33.424 1.00 18.81 ? 355 VAL A CA 1 ATOM 2755 C C . VAL A 1 355 ? 33.142 53.399 33.333 1.00 18.86 ? 355 VAL A C 1 ATOM 2756 O O . VAL A 1 355 ? 32.800 52.338 33.900 1.00 20.15 ? 355 VAL A O 1 ATOM 2757 C CB . VAL A 1 355 ? 34.655 54.942 34.521 1.00 19.91 ? 355 VAL A CB 1 ATOM 2758 C CG1 . VAL A 1 355 ? 34.063 54.415 35.833 1.00 27.70 ? 355 VAL A CG1 1 ATOM 2759 C CG2 . VAL A 1 355 ? 36.140 55.309 34.745 1.00 22.23 ? 355 VAL A CG2 1 ATOM 2760 N N . ASN A 1 356 ? 32.290 54.151 32.651 1.00 18.04 ? 356 ASN A N 1 ATOM 2761 C CA . ASN A 1 356 ? 30.916 53.718 32.525 1.00 17.40 ? 356 ASN A CA 1 ATOM 2762 C C . ASN A 1 356 ? 30.784 52.423 31.705 1.00 19.31 ? 356 ASN A C 1 ATOM 2763 O O . ASN A 1 356 ? 30.061 51.488 32.106 1.00 17.34 ? 356 ASN A O 1 ATOM 2764 C CB . ASN A 1 356 ? 30.045 54.859 32.042 1.00 17.83 ? 356 ASN A CB 1 ATOM 2765 C CG . ASN A 1 356 ? 29.801 55.851 33.133 1.00 20.75 ? 356 ASN A CG 1 ATOM 2766 O OD1 . ASN A 1 356 ? 29.110 55.525 34.110 1.00 19.50 ? 356 ASN A OD1 1 ATOM 2767 N ND2 . ASN A 1 356 ? 30.401 57.046 33.035 1.00 18.84 ? 356 ASN A ND2 1 ATOM 2768 N N . TYR A 1 357 ? 31.498 52.329 30.586 1.00 17.30 ? 357 TYR A N 1 ATOM 2769 C CA . TYR A 1 357 ? 31.413 51.098 29.824 1.00 16.83 ? 357 TYR A CA 1 ATOM 2770 C C . TYR A 1 357 ? 32.044 49.925 30.579 1.00 17.04 ? 357 TYR A C 1 ATOM 2771 O O . TYR A 1 357 ? 31.551 48.793 30.495 1.00 17.25 ? 357 TYR A O 1 ATOM 2772 C CB . TYR A 1 357 ? 32.051 51.280 28.425 1.00 15.37 ? 357 TYR A CB 1 ATOM 2773 C CG . TYR A 1 357 ? 31.053 51.813 27.428 1.00 15.57 ? 357 TYR A CG 1 ATOM 2774 C CD1 . TYR A 1 357 ? 30.210 50.926 26.724 1.00 14.66 ? 357 TYR A CD1 1 ATOM 2775 C CD2 . TYR A 1 357 ? 30.879 53.191 27.235 1.00 15.29 ? 357 TYR A CD2 1 ATOM 2776 C CE1 . TYR A 1 357 ? 29.233 51.387 25.877 1.00 15.39 ? 357 TYR A CE1 1 ATOM 2777 C CE2 . TYR A 1 357 ? 29.883 53.670 26.375 1.00 15.74 ? 357 TYR A CE2 1 ATOM 2778 C CZ . TYR A 1 357 ? 29.054 52.764 25.694 1.00 15.37 ? 357 TYR A CZ 1 ATOM 2779 O OH . TYR A 1 357 ? 28.072 53.217 24.867 1.00 16.22 ? 357 TYR A OH 1 ATOM 2780 N N . GLU A 1 358 ? 33.117 50.160 31.331 1.00 16.64 ? 358 GLU A N 1 ATOM 2781 C CA . GLU A 1 358 ? 33.694 49.050 32.120 1.00 16.48 ? 358 GLU A CA 1 ATOM 2782 C C . GLU A 1 358 ? 32.630 48.505 33.117 1.00 16.77 ? 358 GLU A C 1 ATOM 2783 O O . GLU A 1 358 ? 32.544 47.305 33.310 1.00 17.38 ? 358 GLU A O 1 ATOM 2784 C CB . GLU A 1 358 ? 34.888 49.549 32.941 1.00 17.62 ? 358 GLU A CB 1 ATOM 2785 C CG . GLU A 1 358 ? 36.187 49.695 32.141 1.00 19.48 ? 358 GLU A CG 1 ATOM 2786 C CD . GLU A 1 358 ? 37.396 50.091 33.005 1.00 25.53 ? 358 GLU A CD 1 ATOM 2787 O OE1 . GLU A 1 358 ? 37.344 49.974 34.252 1.00 29.87 ? 358 GLU A OE1 1 ATOM 2788 O OE2 . GLU A 1 358 ? 38.442 50.485 32.464 1.00 23.90 ? 358 GLU A OE2 1 ATOM 2789 N N . ARG A 1 359 ? 31.827 49.391 33.710 1.00 17.92 ? 359 ARG A N 1 ATOM 2790 C CA . ARG A 1 359 ? 30.796 48.918 34.655 1.00 18.51 ? 359 ARG A CA 1 ATOM 2791 C C . ARG A 1 359 ? 29.725 48.127 33.919 1.00 17.49 ? 359 ARG A C 1 ATOM 2792 O O . ARG A 1 359 ? 29.247 47.113 34.424 1.00 18.81 ? 359 ARG A O 1 ATOM 2793 C CB . ARG A 1 359 ? 30.144 50.068 35.392 1.00 18.08 ? 359 ARG A CB 1 ATOM 2794 C CG . ARG A 1 359 ? 31.034 50.780 36.364 1.00 23.36 ? 359 ARG A CG 1 ATOM 2795 C CD . ARG A 1 359 ? 30.328 51.997 36.892 1.00 29.71 ? 359 ARG A CD 1 ATOM 2796 N NE . ARG A 1 359 ? 31.237 52.843 37.651 1.00 32.24 ? 359 ARG A NE 1 ATOM 2797 C CZ . ARG A 1 359 ? 31.316 54.165 37.510 1.00 35.07 ? 359 ARG A CZ 1 ATOM 2798 N NH1 . ARG A 1 359 ? 30.539 54.812 36.624 1.00 31.98 ? 359 ARG A NH1 1 ATOM 2799 N NH2 . ARG A 1 359 ? 32.172 54.840 38.274 1.00 38.19 ? 359 ARG A NH2 1 ATOM 2800 N N . LEU A 1 360 ? 29.348 48.571 32.721 1.00 16.75 ? 360 LEU A N 1 ATOM 2801 C CA . LEU A 1 360 ? 28.380 47.831 31.938 1.00 15.61 ? 360 LEU A CA 1 ATOM 2802 C C . LEU A 1 360 ? 28.963 46.457 31.562 1.00 18.38 ? 360 LEU A C 1 ATOM 2803 O O . LEU A 1 360 ? 28.273 45.431 31.704 1.00 18.78 ? 360 LEU A O 1 ATOM 2804 C CB . LEU A 1 360 ? 27.996 48.643 30.683 1.00 17.96 ? 360 LEU A CB 1 ATOM 2805 C CG . LEU A 1 360 ? 27.140 49.888 31.006 1.00 16.41 ? 360 LEU A CG 1 ATOM 2806 C CD1 . LEU A 1 360 ? 27.176 50.890 29.861 1.00 20.05 ? 360 LEU A CD1 1 ATOM 2807 C CD2 . LEU A 1 360 ? 25.670 49.499 31.232 1.00 18.65 ? 360 LEU A CD2 1 ATOM 2808 N N . PHE A 1 361 ? 30.207 46.404 31.083 1.00 17.22 ? 361 PHE A N 1 ATOM 2809 C CA . PHE A 1 361 ? 30.793 45.126 30.699 1.00 16.55 ? 361 PHE A CA 1 ATOM 2810 C C . PHE A 1 361 ? 30.876 44.158 31.881 1.00 18.52 ? 361 PHE A C 1 ATOM 2811 O O . PHE A 1 361 ? 30.576 42.977 31.723 1.00 19.29 ? 361 PHE A O 1 ATOM 2812 C CB . PHE A 1 361 ? 32.225 45.283 30.132 1.00 16.02 ? 361 PHE A CB 1 ATOM 2813 C CG . PHE A 1 361 ? 32.309 46.103 28.869 1.00 17.53 ? 361 PHE A CG 1 ATOM 2814 C CD1 . PHE A 1 361 ? 31.216 46.249 28.016 1.00 17.12 ? 361 PHE A CD1 1 ATOM 2815 C CD2 . PHE A 1 361 ? 33.514 46.734 28.570 1.00 16.41 ? 361 PHE A CD2 1 ATOM 2816 C CE1 . PHE A 1 361 ? 31.330 47.024 26.862 1.00 16.75 ? 361 PHE A CE1 1 ATOM 2817 C CE2 . PHE A 1 361 ? 33.641 47.528 27.403 1.00 18.02 ? 361 PHE A CE2 1 ATOM 2818 C CZ . PHE A 1 361 ? 32.550 47.658 26.567 1.00 17.59 ? 361 PHE A CZ 1 ATOM 2819 N N . GLU A 1 362 ? 31.319 44.643 33.049 1.00 18.57 ? 362 GLU A N 1 ATOM 2820 C CA . GLU A 1 362 ? 31.431 43.722 34.171 1.00 18.96 ? 362 GLU A CA 1 ATOM 2821 C C . GLU A 1 362 ? 30.054 43.118 34.512 1.00 19.86 ? 362 GLU A C 1 ATOM 2822 O O . GLU A 1 362 ? 29.942 41.918 34.729 1.00 18.16 ? 362 GLU A O 1 ATOM 2823 C CB . GLU A 1 362 ? 32.022 44.412 35.411 1.00 21.83 ? 362 GLU A CB 1 ATOM 2824 C CG . GLU A 1 362 ? 32.157 43.366 36.529 1.00 24.13 ? 362 GLU A CG 1 ATOM 2825 C CD . GLU A 1 362 ? 32.589 43.923 37.865 1.00 31.76 ? 362 GLU A CD 1 ATOM 2826 O OE1 . GLU A 1 362 ? 32.958 45.114 37.924 1.00 34.22 ? 362 GLU A OE1 1 ATOM 2827 O OE2 . GLU A 1 362 ? 32.549 43.143 38.847 1.00 32.34 ? 362 GLU A OE2 1 ATOM 2828 N N . HIS A 1 363 ? 29.017 43.935 34.519 1.00 17.48 ? 363 HIS A N 1 ATOM 2829 C CA . HIS A 1 363 ? 27.702 43.413 34.818 1.00 20.87 ? 363 HIS A CA 1 ATOM 2830 C C . HIS A 1 363 ? 27.168 42.485 33.733 1.00 18.85 ? 363 HIS A C 1 ATOM 2831 O O . HIS A 1 363 ? 26.758 41.365 34.007 1.00 21.04 ? 363 HIS A O 1 ATOM 2832 C CB . HIS A 1 363 ? 26.717 44.538 35.020 1.00 21.44 ? 363 HIS A CB 1 ATOM 2833 C CG . HIS A 1 363 ? 25.334 44.067 35.351 1.00 21.85 ? 363 HIS A CG 1 ATOM 2834 N ND1 . HIS A 1 363 ? 24.994 43.594 36.609 1.00 26.50 ? 363 HIS A ND1 1 ATOM 2835 C CD2 . HIS A 1 363 ? 24.222 43.964 34.593 1.00 23.90 ? 363 HIS A CD2 1 ATOM 2836 C CE1 . HIS A 1 363 ? 23.725 43.221 36.595 1.00 23.50 ? 363 HIS A CE1 1 ATOM 2837 N NE2 . HIS A 1 363 ? 23.231 43.435 35.391 1.00 25.35 ? 363 HIS A NE2 1 ATOM 2838 N N . ILE A 1 364 ? 27.197 42.932 32.485 1.00 18.65 ? 364 ILE A N 1 ATOM 2839 C CA . ILE A 1 364 ? 26.651 42.139 31.411 1.00 18.88 ? 364 ILE A CA 1 ATOM 2840 C C . ILE A 1 364 ? 27.345 40.808 31.245 1.00 19.03 ? 364 ILE A C 1 ATOM 2841 O O . ILE A 1 364 ? 26.686 39.745 31.093 1.00 19.91 ? 364 ILE A O 1 ATOM 2842 C CB . ILE A 1 364 ? 26.738 42.941 30.072 1.00 18.69 ? 364 ILE A CB 1 ATOM 2843 C CG1 . ILE A 1 364 ? 25.743 44.108 30.078 1.00 19.06 ? 364 ILE A CG1 1 ATOM 2844 C CG2 . ILE A 1 364 ? 26.454 41.989 28.914 1.00 18.27 ? 364 ILE A CG2 1 ATOM 2845 C CD1 . ILE A 1 364 ? 26.034 45.205 29.053 1.00 20.41 ? 364 ILE A CD1 1 ATOM 2846 N N . ASN A 1 365 ? 28.654 40.817 31.310 1.00 17.68 ? 365 ASN A N 1 ATOM 2847 C CA . ASN A 1 365 ? 29.424 39.593 31.080 1.00 16.82 ? 365 ASN A CA 1 ATOM 2848 C C . ASN A 1 365 ? 29.298 38.579 32.214 1.00 21.90 ? 365 ASN A C 1 ATOM 2849 O O . ASN A 1 365 ? 29.631 37.407 32.042 1.00 22.40 ? 365 ASN A O 1 ATOM 2850 C CB . ASN A 1 365 ? 30.898 39.913 30.859 1.00 18.27 ? 365 ASN A CB 1 ATOM 2851 C CG . ASN A 1 365 ? 31.122 40.737 29.612 1.00 16.94 ? 365 ASN A CG 1 ATOM 2852 O OD1 . ASN A 1 365 ? 30.202 40.929 28.802 1.00 19.04 ? 365 ASN A OD1 1 ATOM 2853 N ND2 . ASN A 1 365 ? 32.349 41.239 29.464 1.00 16.54 ? 365 ASN A ND2 1 ATOM 2854 N N . SER A 1 366 ? 28.821 39.057 33.359 1.00 24.31 ? 366 SER A N 1 ATOM 2855 C CA . SER A 1 366 ? 28.681 38.181 34.533 1.00 27.37 ? 366 SER A CA 1 ATOM 2856 C C . SER A 1 366 ? 27.258 37.681 34.719 1.00 29.01 ? 366 SER A C 1 ATOM 2857 O O . SER A 1 366 ? 27.030 36.803 35.548 1.00 30.82 ? 366 SER A O 1 ATOM 2858 C CB . SER A 1 366 ? 29.140 38.913 35.814 1.00 29.69 ? 366 SER A CB 1 ATOM 2859 O OG . SER A 1 366 ? 28.205 39.920 36.159 1.00 31.72 ? 366 SER A OG 1 ATOM 2860 N N . GLN A 1 367 ? 26.314 38.219 33.962 1.00 29.52 ? 367 GLN A N 1 ATOM 2861 C CA . GLN A 1 367 ? 24.904 37.834 34.019 1.00 29.91 ? 367 GLN A CA 1 ATOM 2862 C C . GLN A 1 367 ? 24.631 36.844 32.899 1.00 29.14 ? 367 GLN A C 1 ATOM 2863 O O . GLN A 1 367 ? 24.279 37.233 31.774 1.00 27.93 ? 367 GLN A O 1 ATOM 2864 C CB . GLN A 1 367 ? 24.005 39.054 33.807 1.00 32.12 ? 367 GLN A CB 1 ATOM 2865 C CG . GLN A 1 367 ? 24.052 40.026 34.955 1.00 37.26 ? 367 GLN A CG 1 ATOM 2866 C CD . GLN A 1 367 ? 23.573 39.375 36.225 1.00 40.21 ? 367 GLN A CD 1 ATOM 2867 O OE1 . GLN A 1 367 ? 22.411 38.961 36.312 1.00 40.74 ? 367 GLN A OE1 1 ATOM 2868 N NE2 . GLN A 1 367 ? 24.461 39.268 37.222 1.00 40.91 ? 367 GLN A NE2 1 ATOM 2869 N N . ALA A 1 368 ? 24.738 35.557 33.215 1.00 28.76 ? 368 ALA A N 1 ATOM 2870 C CA . ALA A 1 368 ? 24.534 34.531 32.198 1.00 26.94 ? 368 ALA A CA 1 ATOM 2871 C C . ALA A 1 368 ? 23.287 34.682 31.338 1.00 26.62 ? 368 ALA A C 1 ATOM 2872 O O . ALA A 1 368 ? 23.306 34.352 30.140 1.00 26.57 ? 368 ALA A O 1 ATOM 2873 C CB . ALA A 1 368 ? 24.521 33.166 32.856 1.00 27.96 ? 368 ALA A CB 1 ATOM 2874 N N . HIS A 1 369 ? 22.215 35.189 31.936 1.00 26.09 ? 369 HIS A N 1 ATOM 2875 C CA . HIS A 1 369 ? 20.956 35.371 31.238 1.00 26.00 ? 369 HIS A CA 1 ATOM 2876 C C . HIS A 1 369 ? 21.039 36.238 29.976 1.00 25.16 ? 369 HIS A C 1 ATOM 2877 O O . HIS A 1 369 ? 20.176 36.142 29.105 1.00 26.11 ? 369 HIS A O 1 ATOM 2878 C CB A HIS A 1 369 ? 19.898 35.925 32.221 0.50 27.64 ? 369 HIS A CB 1 ATOM 2879 C CB B HIS A 1 369 ? 19.803 35.767 32.076 0.50 28.13 ? 369 HIS A CB 1 ATOM 2880 C CG A HIS A 1 369 ? 20.204 37.294 32.755 0.50 26.87 ? 369 HIS A CG 1 ATOM 2881 C CG B HIS A 1 369 ? 19.816 37.232 32.388 0.50 28.67 ? 369 HIS A CG 1 ATOM 2882 N ND1 A HIS A 1 369 ? 19.850 38.449 32.087 0.50 29.24 ? 369 HIS A ND1 1 ATOM 2883 N ND1 B HIS A 1 369 ? 19.307 38.182 31.527 0.50 30.44 ? 369 HIS A ND1 1 ATOM 2884 C CD2 A HIS A 1 369 ? 20.836 37.692 33.884 0.50 28.12 ? 369 HIS A CD2 1 ATOM 2885 C CD2 B HIS A 1 369 ? 20.307 37.911 33.450 0.50 29.69 ? 369 HIS A CD2 1 ATOM 2886 C CE1 A HIS A 1 369 ? 20.249 39.498 32.782 0.50 28.69 ? 369 HIS A CE1 1 ATOM 2887 C CE1 B HIS A 1 369 ? 19.488 39.385 32.046 0.50 28.01 ? 369 HIS A CE1 1 ATOM 2888 N NE2 A HIS A 1 369 ? 20.851 39.068 33.877 0.50 27.40 ? 369 HIS A NE2 1 ATOM 2889 N NE2 B HIS A 1 369 ? 20.093 39.249 33.212 0.50 29.87 ? 369 HIS A NE2 1 ATOM 2890 N N . PHE A 1 370 ? 22.068 37.077 29.868 1.00 25.52 ? 370 PHE A N 1 ATOM 2891 C CA . PHE A 1 370 ? 22.203 37.939 28.671 1.00 23.71 ? 370 PHE A CA 1 ATOM 2892 C C . PHE A 1 370 ? 22.866 37.167 27.535 1.00 21.56 ? 370 PHE A C 1 ATOM 2893 O O . PHE A 1 370 ? 22.649 37.464 26.370 1.00 20.80 ? 370 PHE A O 1 ATOM 2894 C CB . PHE A 1 370 ? 23.090 39.172 28.930 1.00 24.82 ? 370 PHE A CB 1 ATOM 2895 C CG . PHE A 1 370 ? 22.440 40.255 29.731 1.00 24.12 ? 370 PHE A CG 1 ATOM 2896 C CD1 . PHE A 1 370 ? 21.247 40.834 29.309 1.00 25.48 ? 370 PHE A CD1 1 ATOM 2897 C CD2 . PHE A 1 370 ? 23.069 40.740 30.853 1.00 25.61 ? 370 PHE A CD2 1 ATOM 2898 C CE1 . PHE A 1 370 ? 20.691 41.925 30.036 1.00 27.05 ? 370 PHE A CE1 1 ATOM 2899 C CE2 . PHE A 1 370 ? 22.527 41.814 31.572 1.00 26.07 ? 370 PHE A CE2 1 ATOM 2900 C CZ . PHE A 1 370 ? 21.356 42.393 31.164 1.00 25.56 ? 370 PHE A CZ 1 ATOM 2901 N N . ASN A 1 371 ? 23.691 36.195 27.900 1.00 19.53 ? 371 ASN A N 1 ATOM 2902 C CA . ASN A 1 371 ? 24.452 35.402 26.945 1.00 19.04 ? 371 ASN A CA 1 ATOM 2903 C C . ASN A 1 371 ? 25.233 36.301 26.004 1.00 17.53 ? 371 ASN A C 1 ATOM 2904 O O . ASN A 1 371 ? 25.242 36.115 24.793 1.00 19.73 ? 371 ASN A O 1 ATOM 2905 C CB . ASN A 1 371 ? 23.528 34.451 26.173 1.00 18.93 ? 371 ASN A CB 1 ATOM 2906 C CG . ASN A 1 371 ? 22.887 33.414 27.093 1.00 20.21 ? 371 ASN A CG 1 ATOM 2907 O OD1 . ASN A 1 371 ? 23.589 32.588 27.703 1.00 22.81 ? 371 ASN A OD1 1 ATOM 2908 N ND2 . ASN A 1 371 ? 21.582 33.491 27.221 1.00 23.72 ? 371 ASN A ND2 1 ATOM 2909 N N . VAL A 1 372 ? 25.923 37.262 26.610 1.00 16.83 ? 372 VAL A N 1 ATOM 2910 C CA . VAL A 1 372 ? 26.749 38.232 25.887 1.00 17.56 ? 372 VAL A CA 1 ATOM 2911 C C . VAL A 1 372 ? 28.129 38.311 26.503 1.00 18.73 ? 372 VAL A C 1 ATOM 2912 O O . VAL A 1 372 ? 28.261 38.183 27.732 1.00 19.26 ? 372 VAL A O 1 ATOM 2913 C CB . VAL A 1 372 ? 26.100 39.643 25.988 1.00 17.16 ? 372 VAL A CB 1 ATOM 2914 C CG1 . VAL A 1 372 ? 27.092 40.745 25.411 1.00 16.02 ? 372 VAL A CG1 1 ATOM 2915 C CG2 . VAL A 1 372 ? 24.761 39.674 25.197 1.00 18.10 ? 372 VAL A CG2 1 ATOM 2916 N N . GLN A 1 373 ? 29.175 38.479 25.672 1.00 16.92 ? 373 GLN A N 1 ATOM 2917 C CA . GLN A 1 373 ? 30.540 38.727 26.150 1.00 17.29 ? 373 GLN A CA 1 ATOM 2918 C C . GLN A 1 373 ? 30.916 40.015 25.398 1.00 16.21 ? 373 GLN A C 1 ATOM 2919 O O . GLN A 1 373 ? 31.090 39.996 24.156 1.00 17.18 ? 373 GLN A O 1 ATOM 2920 C CB . GLN A 1 373 ? 31.508 37.602 25.780 1.00 17.06 ? 373 GLN A CB 1 ATOM 2921 C CG . GLN A 1 373 ? 32.993 37.936 26.083 1.00 21.09 ? 373 GLN A CG 1 ATOM 2922 C CD . GLN A 1 373 ? 33.245 38.274 27.552 1.00 24.85 ? 373 GLN A CD 1 ATOM 2923 O OE1 . GLN A 1 373 ? 32.537 37.786 28.432 1.00 25.26 ? 373 GLN A OE1 1 ATOM 2924 N NE2 . GLN A 1 373 ? 34.255 39.100 27.817 1.00 24.30 ? 373 GLN A NE2 1 ATOM 2925 N N . ALA A 1 374 ? 30.994 41.132 26.109 1.00 15.09 ? 374 ALA A N 1 ATOM 2926 C CA . ALA A 1 374 ? 31.282 42.430 25.514 1.00 15.90 ? 374 ALA A CA 1 ATOM 2927 C C . ALA A 1 374 ? 32.589 43.011 25.993 1.00 15.94 ? 374 ALA A C 1 ATOM 2928 O O . ALA A 1 374 ? 32.950 42.865 27.168 1.00 16.33 ? 374 ALA A O 1 ATOM 2929 C CB . ALA A 1 374 ? 30.147 43.384 25.840 1.00 14.17 ? 374 ALA A CB 1 ATOM 2930 N N . GLN A 1 375 ? 33.303 43.711 25.111 1.00 14.97 ? 375 GLN A N 1 ATOM 2931 C CA . GLN A 1 375 ? 34.586 44.292 25.480 1.00 15.18 ? 375 GLN A CA 1 ATOM 2932 C C . GLN A 1 375 ? 34.980 45.382 24.514 1.00 15.28 ? 375 GLN A C 1 ATOM 2933 O O . GLN A 1 375 ? 34.434 45.466 23.426 1.00 16.89 ? 375 GLN A O 1 ATOM 2934 C CB . GLN A 1 375 ? 35.688 43.227 25.404 1.00 15.66 ? 375 GLN A CB 1 ATOM 2935 C CG . GLN A 1 375 ? 35.681 42.466 24.044 1.00 18.92 ? 375 GLN A CG 1 ATOM 2936 C CD . GLN A 1 375 ? 34.944 41.126 24.116 1.00 25.08 ? 375 GLN A CD 1 ATOM 2937 O OE1 . GLN A 1 375 ? 35.323 40.248 24.918 1.00 26.30 ? 375 GLN A OE1 1 ATOM 2938 N NE2 . GLN A 1 375 ? 33.889 40.951 23.284 1.00 22.53 ? 375 GLN A NE2 1 ATOM 2939 N N . PHE A 1 376 ? 35.932 46.212 24.931 1.00 14.36 ? 376 PHE A N 1 ATOM 2940 C CA . PHE A 1 376 ? 36.498 47.184 23.980 1.00 14.59 ? 376 PHE A CA 1 ATOM 2941 C C . PHE A 1 376 ? 37.291 46.339 22.978 1.00 15.28 ? 376 PHE A C 1 ATOM 2942 O O . PHE A 1 376 ? 37.913 45.336 23.323 1.00 16.44 ? 376 PHE A O 1 ATOM 2943 C CB . PHE A 1 376 ? 37.469 48.144 24.695 1.00 12.98 ? 376 PHE A CB 1 ATOM 2944 C CG . PHE A 1 376 ? 36.796 49.064 25.638 1.00 13.63 ? 376 PHE A CG 1 ATOM 2945 C CD1 . PHE A 1 376 ? 35.773 49.913 25.192 1.00 14.03 ? 376 PHE A CD1 1 ATOM 2946 C CD2 . PHE A 1 376 ? 37.162 49.090 27.007 1.00 15.68 ? 376 PHE A CD2 1 ATOM 2947 C CE1 . PHE A 1 376 ? 35.125 50.766 26.106 1.00 17.31 ? 376 PHE A CE1 1 ATOM 2948 C CE2 . PHE A 1 376 ? 36.505 49.947 27.891 1.00 18.20 ? 376 PHE A CE2 1 ATOM 2949 C CZ . PHE A 1 376 ? 35.511 50.766 27.461 1.00 18.76 ? 376 PHE A CZ 1 ATOM 2950 N N . GLY A 1 377 ? 37.288 46.778 21.721 1.00 14.91 ? 377 GLY A N 1 ATOM 2951 C CA . GLY A 1 377 ? 38.043 46.056 20.723 1.00 15.03 ? 377 GLY A CA 1 ATOM 2952 C C . GLY A 1 377 ? 38.474 47.007 19.617 1.00 13.38 ? 377 GLY A C 1 ATOM 2953 O O . GLY A 1 377 ? 38.164 48.180 19.622 1.00 15.18 ? 377 GLY A O 1 ATOM 2954 N N . THR A 1 378 ? 39.217 46.447 18.662 1.00 14.70 ? 378 THR A N 1 ATOM 2955 C CA . THR A 1 378 ? 39.649 47.203 17.506 1.00 15.98 ? 378 THR A CA 1 ATOM 2956 C C . THR A 1 378 ? 38.890 46.664 16.298 1.00 13.74 ? 378 THR A C 1 ATOM 2957 O O . THR A 1 378 ? 38.164 45.650 16.357 1.00 14.64 ? 378 THR A O 1 ATOM 2958 C CB . THR A 1 378 ? 41.132 47.068 17.236 1.00 16.09 ? 378 THR A CB 1 ATOM 2959 O OG1 . THR A 1 378 ? 41.435 45.720 16.858 1.00 16.22 ? 378 THR A OG1 1 ATOM 2960 C CG2 . THR A 1 378 ? 41.944 47.415 18.492 1.00 17.82 ? 378 THR A CG2 1 ATOM 2961 N N . LEU A 1 379 ? 39.053 47.363 15.175 1.00 13.73 ? 379 LEU A N 1 ATOM 2962 C CA . LEU A 1 379 ? 38.357 46.944 13.943 1.00 13.32 ? 379 LEU A CA 1 ATOM 2963 C C . LEU A 1 379 ? 38.850 45.594 13.443 1.00 14.18 ? 379 LEU A C 1 ATOM 2964 O O . LEU A 1 379 ? 38.081 44.724 13.055 1.00 13.79 ? 379 LEU A O 1 ATOM 2965 C CB . LEU A 1 379 ? 38.556 48.051 12.896 1.00 14.40 ? 379 LEU A CB 1 ATOM 2966 C CG . LEU A 1 379 ? 37.812 47.825 11.565 1.00 13.46 ? 379 LEU A CG 1 ATOM 2967 C CD1 . LEU A 1 379 ? 36.315 47.779 11.824 1.00 15.16 ? 379 LEU A CD1 1 ATOM 2968 C CD2 . LEU A 1 379 ? 38.140 48.943 10.594 1.00 14.99 ? 379 LEU A CD2 1 ATOM 2969 N N . GLN A 1 380 ? 40.167 45.402 13.469 1.00 13.05 ? 380 GLN A N 1 ATOM 2970 C CA . GLN A 1 380 ? 40.729 44.121 13.013 1.00 13.82 ? 380 GLN A CA 1 ATOM 2971 C C . GLN A 1 380 ? 40.224 42.967 13.892 1.00 14.73 ? 380 GLN A C 1 ATOM 2972 O O . GLN A 1 380 ? 39.954 41.877 13.401 1.00 15.84 ? 380 GLN A O 1 ATOM 2973 C CB . GLN A 1 380 ? 42.250 44.162 13.003 1.00 16.54 ? 380 GLN A CB 1 ATOM 2974 C CG . GLN A 1 380 ? 42.868 42.875 12.502 1.00 17.76 ? 380 GLN A CG 1 ATOM 2975 C CD . GLN A 1 380 ? 42.577 42.678 11.049 1.00 20.51 ? 380 GLN A CD 1 ATOM 2976 O OE1 . GLN A 1 380 ? 42.620 43.638 10.273 1.00 21.14 ? 380 GLN A OE1 1 ATOM 2977 N NE2 . GLN A 1 380 ? 42.270 41.428 10.658 1.00 24.60 ? 380 GLN A NE2 1 ATOM 2978 N N . GLU A 1 381 ? 40.097 43.222 15.190 1.00 15.18 ? 381 GLU A N 1 ATOM 2979 C CA . GLU A 1 381 ? 39.598 42.184 16.080 1.00 15.69 ? 381 GLU A CA 1 ATOM 2980 C C . GLU A 1 381 ? 38.188 41.770 15.677 1.00 13.87 ? 381 GLU A C 1 ATOM 2981 O O . GLU A 1 381 ? 37.855 40.592 15.710 1.00 16.05 ? 381 GLU A O 1 ATOM 2982 C CB . GLU A 1 381 ? 39.521 42.700 17.508 1.00 15.87 ? 381 GLU A CB 1 ATOM 2983 C CG . GLU A 1 381 ? 40.809 42.655 18.307 1.00 22.12 ? 381 GLU A CG 1 ATOM 2984 C CD . GLU A 1 381 ? 40.470 42.995 19.757 1.00 26.33 ? 381 GLU A CD 1 ATOM 2985 O OE1 . GLU A 1 381 ? 40.386 44.173 20.045 1.00 25.13 ? 381 GLU A OE1 1 ATOM 2986 O OE2 . GLU A 1 381 ? 40.240 42.082 20.612 1.00 31.55 ? 381 GLU A OE2 1 ATOM 2987 N N . TYR A 1 382 ? 37.332 42.749 15.363 1.00 13.24 ? 382 TYR A N 1 ATOM 2988 C CA . TYR A 1 382 ? 35.993 42.450 14.900 1.00 13.06 ? 382 TYR A CA 1 ATOM 2989 C C . TYR A 1 382 ? 36.034 41.548 13.664 1.00 14.09 ? 382 TYR A C 1 ATOM 2990 O O . TYR A 1 382 ? 35.388 40.510 13.591 1.00 13.81 ? 382 TYR A O 1 ATOM 2991 C CB . TYR A 1 382 ? 35.226 43.738 14.531 1.00 14.38 ? 382 TYR A CB 1 ATOM 2992 C CG . TYR A 1 382 ? 33.924 43.440 13.848 1.00 11.82 ? 382 TYR A CG 1 ATOM 2993 C CD1 . TYR A 1 382 ? 32.854 42.859 14.545 1.00 14.60 ? 382 TYR A CD1 1 ATOM 2994 C CD2 . TYR A 1 382 ? 33.762 43.680 12.481 1.00 13.42 ? 382 TYR A CD2 1 ATOM 2995 C CE1 . TYR A 1 382 ? 31.665 42.530 13.880 1.00 14.40 ? 382 TYR A CE1 1 ATOM 2996 C CE2 . TYR A 1 382 ? 32.589 43.346 11.839 1.00 14.22 ? 382 TYR A CE2 1 ATOM 2997 C CZ . TYR A 1 382 ? 31.545 42.771 12.547 1.00 14.80 ? 382 TYR A CZ 1 ATOM 2998 O OH . TYR A 1 382 ? 30.354 42.419 11.936 1.00 14.22 ? 382 TYR A OH 1 ATOM 2999 N N . PHE A 1 383 ? 36.777 41.984 12.645 1.00 12.90 ? 383 PHE A N 1 ATOM 3000 C CA . PHE A 1 383 ? 36.826 41.187 11.420 1.00 12.98 ? 383 PHE A CA 1 ATOM 3001 C C . PHE A 1 383 ? 37.409 39.804 11.627 1.00 12.43 ? 383 PHE A C 1 ATOM 3002 O O . PHE A 1 383 ? 36.898 38.853 11.036 1.00 14.02 ? 383 PHE A O 1 ATOM 3003 C CB . PHE A 1 383 ? 37.611 41.951 10.339 1.00 12.42 ? 383 PHE A CB 1 ATOM 3004 C CG . PHE A 1 383 ? 36.827 43.086 9.709 1.00 12.60 ? 383 PHE A CG 1 ATOM 3005 C CD1 . PHE A 1 383 ? 35.606 42.863 9.069 1.00 14.45 ? 383 PHE A CD1 1 ATOM 3006 C CD2 . PHE A 1 383 ? 37.352 44.387 9.745 1.00 12.51 ? 383 PHE A CD2 1 ATOM 3007 C CE1 . PHE A 1 383 ? 34.895 43.934 8.450 1.00 15.34 ? 383 PHE A CE1 1 ATOM 3008 C CE2 . PHE A 1 383 ? 36.668 45.456 9.153 1.00 13.60 ? 383 PHE A CE2 1 ATOM 3009 C CZ . PHE A 1 383 ? 35.442 45.237 8.498 1.00 14.05 ? 383 PHE A CZ 1 ATOM 3010 N N . ASP A 1 384 ? 38.449 39.693 12.460 1.00 14.24 ? 384 ASP A N 1 ATOM 3011 C CA . ASP A 1 384 ? 39.016 38.371 12.719 1.00 15.53 ? 384 ASP A CA 1 ATOM 3012 C C . ASP A 1 384 ? 37.958 37.441 13.332 1.00 13.24 ? 384 ASP A C 1 ATOM 3013 O O . ASP A 1 384 ? 37.851 36.263 12.956 1.00 16.72 ? 384 ASP A O 1 ATOM 3014 C CB . ASP A 1 384 ? 40.204 38.462 13.682 1.00 15.95 ? 384 ASP A CB 1 ATOM 3015 C CG . ASP A 1 384 ? 41.425 39.102 13.054 1.00 19.54 ? 384 ASP A CG 1 ATOM 3016 O OD1 . ASP A 1 384 ? 41.548 39.184 11.804 1.00 21.10 ? 384 ASP A OD1 1 ATOM 3017 O OD2 . ASP A 1 384 ? 42.276 39.516 13.867 1.00 22.79 ? 384 ASP A OD2 1 ATOM 3018 N N . ALA A 1 385 ? 37.152 37.960 14.244 1.00 13.27 ? 385 ALA A N 1 ATOM 3019 C CA . ALA A 1 385 ? 36.151 37.136 14.878 1.00 15.05 ? 385 ALA A CA 1 ATOM 3020 C C . ALA A 1 385 ? 35.036 36.800 13.887 1.00 17.01 ? 385 ALA A C 1 ATOM 3021 O O . ALA A 1 385 ? 34.522 35.688 13.885 1.00 17.57 ? 385 ALA A O 1 ATOM 3022 C CB . ALA A 1 385 ? 35.624 37.873 16.127 1.00 14.81 ? 385 ALA A CB 1 ATOM 3023 N N . VAL A 1 386 ? 34.653 37.750 13.026 1.00 14.21 ? 386 VAL A N 1 ATOM 3024 C CA . VAL A 1 386 ? 33.639 37.436 12.031 1.00 13.92 ? 386 VAL A CA 1 ATOM 3025 C C . VAL A 1 386 ? 34.107 36.286 11.121 1.00 15.81 ? 386 VAL A C 1 ATOM 3026 O O . VAL A 1 386 ? 33.337 35.370 10.814 1.00 16.25 ? 386 VAL A O 1 ATOM 3027 C CB . VAL A 1 386 ? 33.359 38.685 11.183 1.00 13.20 ? 386 VAL A CB 1 ATOM 3028 C CG1 . VAL A 1 386 ? 32.512 38.320 9.939 1.00 16.22 ? 386 VAL A CG1 1 ATOM 3029 C CG2 . VAL A 1 386 ? 32.604 39.687 12.007 1.00 16.24 ? 386 VAL A CG2 1 ATOM 3030 N N . HIS A 1 387 ? 35.354 36.352 10.673 1.00 15.40 ? 387 HIS A N 1 ATOM 3031 C CA . HIS A 1 387 ? 35.852 35.295 9.796 1.00 16.50 ? 387 HIS A CA 1 ATOM 3032 C C . HIS A 1 387 ? 36.074 33.972 10.488 1.00 18.53 ? 387 HIS A C 1 ATOM 3033 O O . HIS A 1 387 ? 35.977 32.930 9.836 1.00 18.08 ? 387 HIS A O 1 ATOM 3034 C CB . HIS A 1 387 ? 37.098 35.772 9.033 1.00 17.68 ? 387 HIS A CB 1 ATOM 3035 C CG . HIS A 1 387 ? 36.805 36.882 8.066 1.00 16.00 ? 387 HIS A CG 1 ATOM 3036 N ND1 . HIS A 1 387 ? 35.927 36.729 7.014 1.00 20.78 ? 387 HIS A ND1 1 ATOM 3037 C CD2 . HIS A 1 387 ? 37.209 38.173 8.039 1.00 18.76 ? 387 HIS A CD2 1 ATOM 3038 C CE1 . HIS A 1 387 ? 35.808 37.884 6.376 1.00 21.70 ? 387 HIS A CE1 1 ATOM 3039 N NE2 . HIS A 1 387 ? 36.573 38.775 6.981 1.00 19.46 ? 387 HIS A NE2 1 ATOM 3040 N N . GLN A 1 388 ? 36.316 34.019 11.797 1.00 17.92 ? 388 GLN A N 1 ATOM 3041 C CA . GLN A 1 388 ? 36.430 32.767 12.561 1.00 19.70 ? 388 GLN A CA 1 ATOM 3042 C C . GLN A 1 388 ? 35.033 32.131 12.575 1.00 20.80 ? 388 GLN A C 1 ATOM 3043 O O . GLN A 1 388 ? 34.904 30.920 12.446 1.00 21.50 ? 388 GLN A O 1 ATOM 3044 C CB . GLN A 1 388 ? 36.930 33.083 13.959 1.00 21.60 ? 388 GLN A CB 1 ATOM 3045 C CG . GLN A 1 388 ? 38.430 33.353 13.963 1.00 28.07 ? 388 GLN A CG 1 ATOM 3046 C CD . GLN A 1 388 ? 38.933 34.099 15.221 1.00 35.23 ? 388 GLN A CD 1 ATOM 3047 O OE1 . GLN A 1 388 ? 40.118 34.512 15.295 1.00 38.94 ? 388 GLN A OE1 1 ATOM 3048 N NE2 . GLN A 1 388 ? 38.046 34.278 16.207 1.00 36.48 ? 388 GLN A NE2 1 ATOM 3049 N N . ALA A 1 389 ? 33.986 32.944 12.693 1.00 19.38 ? 389 ALA A N 1 ATOM 3050 C CA . ALA A 1 389 ? 32.583 32.464 12.693 1.00 22.43 ? 389 ALA A CA 1 ATOM 3051 C C . ALA A 1 389 ? 32.239 31.862 11.332 1.00 23.59 ? 389 ALA A C 1 ATOM 3052 O O . ALA A 1 389 ? 31.600 30.800 11.235 1.00 24.62 ? 389 ALA A O 1 ATOM 3053 C CB . ALA A 1 389 ? 31.610 33.623 13.027 1.00 20.38 ? 389 ALA A CB 1 ATOM 3054 N N . GLU A 1 390 ? 32.676 32.540 10.279 1.00 23.06 ? 390 GLU A N 1 ATOM 3055 C CA . GLU A 1 390 ? 32.445 32.094 8.914 1.00 24.81 ? 390 GLU A CA 1 ATOM 3056 C C . GLU A 1 390 ? 33.107 30.728 8.695 1.00 26.89 ? 390 GLU A C 1 ATOM 3057 O O . GLU A 1 390 ? 32.483 29.808 8.138 1.00 27.80 ? 390 GLU A O 1 ATOM 3058 C CB . GLU A 1 390 ? 33.036 33.138 7.954 1.00 22.98 ? 390 GLU A CB 1 ATOM 3059 C CG . GLU A 1 390 ? 32.969 32.792 6.476 1.00 27.86 ? 390 GLU A CG 1 ATOM 3060 C CD . GLU A 1 390 ? 33.725 33.806 5.629 1.00 29.35 ? 390 GLU A CD 1 ATOM 3061 O OE1 . GLU A 1 390 ? 34.586 34.533 6.181 1.00 28.58 ? 390 GLU A OE1 1 ATOM 3062 O OE2 . GLU A 1 390 ? 33.476 33.878 4.415 1.00 31.28 ? 390 GLU A OE2 1 ATOM 3063 N N . ARG A 1 391 ? 34.355 30.596 9.143 1.00 25.88 ? 391 ARG A N 1 ATOM 3064 C CA . ARG A 1 391 ? 35.086 29.343 8.987 1.00 28.72 ? 391 ARG A CA 1 ATOM 3065 C C . ARG A 1 391 ? 34.448 28.247 9.837 1.00 27.89 ? 391 ARG A C 1 ATOM 3066 O O . ARG A 1 391 ? 34.518 27.066 9.475 1.00 31.70 ? 391 ARG A O 1 ATOM 3067 C CB . ARG A 1 391 ? 36.566 29.522 9.364 1.00 30.17 ? 391 ARG A CB 1 ATOM 3068 C CG . ARG A 1 391 ? 37.344 30.403 8.391 1.00 33.48 ? 391 ARG A CG 1 ATOM 3069 C CD . ARG A 1 391 ? 38.856 30.270 8.578 1.00 35.49 ? 391 ARG A CD 1 ATOM 3070 N NE . ARG A 1 391 ? 39.307 30.699 9.901 1.00 38.26 ? 391 ARG A NE 1 ATOM 3071 C CZ . ARG A 1 391 ? 39.535 31.968 10.251 1.00 39.03 ? 391 ARG A CZ 1 ATOM 3072 N NH1 . ARG A 1 391 ? 39.361 32.957 9.379 1.00 38.06 ? 391 ARG A NH1 1 ATOM 3073 N NH2 . ARG A 1 391 ? 39.936 32.245 11.483 1.00 40.20 ? 391 ARG A NH2 1 ATOM 3074 N N . ALA A 1 392 ? 33.800 28.619 10.938 1.00 28.88 ? 392 ALA A N 1 ATOM 3075 C CA . ALA A 1 392 ? 33.147 27.626 11.809 1.00 27.74 ? 392 ALA A CA 1 ATOM 3076 C C . ALA A 1 392 ? 31.829 27.175 11.161 1.00 30.64 ? 392 ALA A C 1 ATOM 3077 O O . ALA A 1 392 ? 31.069 26.377 11.747 1.00 32.73 ? 392 ALA A O 1 ATOM 3078 C CB . ALA A 1 392 ? 32.883 28.214 13.180 1.00 28.14 ? 392 ALA A CB 1 ATOM 3079 N N . GLY A 1 393 ? 31.572 27.691 9.956 1.00 31.15 ? 393 GLY A N 1 ATOM 3080 C CA . GLY A 1 393 ? 30.371 27.351 9.215 1.00 30.36 ? 393 GLY A CA 1 ATOM 3081 C C . GLY A 1 393 ? 29.116 28.030 9.702 1.00 28.94 ? 393 GLY A C 1 ATOM 3082 O O . GLY A 1 393 ? 27.993 27.635 9.360 1.00 30.05 ? 393 GLY A O 1 ATOM 3083 N N . GLN A 1 394 ? 29.270 29.095 10.475 1.00 28.51 ? 394 GLN A N 1 ATOM 3084 C CA . GLN A 1 394 ? 28.071 29.714 10.975 1.00 29.40 ? 394 GLN A CA 1 ATOM 3085 C C . GLN A 1 394 ? 27.429 30.758 10.060 1.00 27.03 ? 394 GLN A C 1 ATOM 3086 O O . GLN A 1 394 ? 26.294 31.174 10.311 1.00 29.05 ? 394 GLN A O 1 ATOM 3087 C CB . GLN A 1 394 ? 28.295 30.220 12.415 1.00 32.45 ? 394 GLN A CB 1 ATOM 3088 C CG . GLN A 1 394 ? 28.912 31.557 12.588 1.00 36.01 ? 394 GLN A CG 1 ATOM 3089 C CD . GLN A 1 394 ? 28.732 32.072 14.021 1.00 35.25 ? 394 GLN A CD 1 ATOM 3090 O OE1 . GLN A 1 394 ? 29.225 31.471 15.003 1.00 34.90 ? 394 GLN A OE1 1 ATOM 3091 N NE2 . GLN A 1 394 ? 28.030 33.188 14.146 1.00 27.90 ? 394 GLN A NE2 1 ATOM 3092 N N . ALA A 1 395 ? 28.110 31.129 8.967 1.00 24.68 ? 395 ALA A N 1 ATOM 3093 C CA . ALA A 1 395 ? 27.562 32.111 8.032 1.00 23.95 ? 395 ALA A CA 1 ATOM 3094 C C . ALA A 1 395 ? 28.246 32.039 6.665 1.00 23.62 ? 395 ALA A C 1 ATOM 3095 O O . ALA A 1 395 ? 29.407 31.660 6.571 1.00 24.65 ? 395 ALA A O 1 ATOM 3096 C CB . ALA A 1 395 ? 27.735 33.540 8.626 1.00 26.23 ? 395 ALA A CB 1 ATOM 3097 N N . GLU A 1 396 ? 27.509 32.370 5.607 1.00 24.27 ? 396 GLU A N 1 ATOM 3098 C CA . GLU A 1 396 ? 28.073 32.456 4.267 1.00 25.35 ? 396 GLU A CA 1 ATOM 3099 C C . GLU A 1 396 ? 27.672 33.880 3.850 1.00 23.51 ? 396 GLU A C 1 ATOM 3100 O O . GLU A 1 396 ? 26.579 34.367 4.182 1.00 26.09 ? 396 GLU A O 1 ATOM 3101 C CB . GLU A 1 396 ? 27.464 31.413 3.324 1.00 30.33 ? 396 GLU A CB 1 ATOM 3102 C CG . GLU A 1 396 ? 25.984 31.591 3.102 1.00 39.19 ? 396 GLU A CG 1 ATOM 3103 C CD . GLU A 1 396 ? 25.354 30.417 2.382 1.00 44.03 ? 396 GLU A CD 1 ATOM 3104 O OE1 . GLU A 1 396 ? 25.841 30.056 1.279 1.00 47.25 ? 396 GLU A OE1 1 ATOM 3105 O OE2 . GLU A 1 396 ? 24.368 29.858 2.922 1.00 47.83 ? 396 GLU A OE2 1 ATOM 3106 N N . PHE A 1 397 ? 28.552 34.552 3.141 1.00 19.16 ? 397 PHE A N 1 ATOM 3107 C CA . PHE A 1 397 ? 28.267 35.933 2.794 1.00 16.24 ? 397 PHE A CA 1 ATOM 3108 C C . PHE A 1 397 ? 27.937 36.103 1.316 1.00 15.32 ? 397 PHE A C 1 ATOM 3109 O O . PHE A 1 397 ? 28.462 35.382 0.486 1.00 19.04 ? 397 PHE A O 1 ATOM 3110 C CB . PHE A 1 397 ? 29.498 36.780 3.150 1.00 17.35 ? 397 PHE A CB 1 ATOM 3111 C CG . PHE A 1 397 ? 29.790 36.836 4.634 1.00 14.47 ? 397 PHE A CG 1 ATOM 3112 C CD1 . PHE A 1 397 ? 28.945 37.537 5.476 1.00 14.15 ? 397 PHE A CD1 1 ATOM 3113 C CD2 . PHE A 1 397 ? 30.861 36.142 5.158 1.00 16.74 ? 397 PHE A CD2 1 ATOM 3114 C CE1 . PHE A 1 397 ? 29.147 37.548 6.856 1.00 15.50 ? 397 PHE A CE1 1 ATOM 3115 C CE2 . PHE A 1 397 ? 31.093 36.128 6.575 1.00 17.68 ? 397 PHE A CE2 1 ATOM 3116 C CZ . PHE A 1 397 ? 30.215 36.841 7.402 1.00 15.37 ? 397 PHE A CZ 1 ATOM 3117 N N . PRO A 1 398 ? 27.030 37.022 1.014 1.00 14.33 ? 398 PRO A N 1 ATOM 3118 C CA . PRO A 1 398 ? 26.640 37.294 -0.377 1.00 15.20 ? 398 PRO A CA 1 ATOM 3119 C C . PRO A 1 398 ? 27.738 38.055 -1.125 1.00 16.10 ? 398 PRO A C 1 ATOM 3120 O O . PRO A 1 398 ? 28.593 38.719 -0.518 1.00 15.21 ? 398 PRO A O 1 ATOM 3121 C CB . PRO A 1 398 ? 25.379 38.133 -0.213 1.00 15.57 ? 398 PRO A CB 1 ATOM 3122 C CG . PRO A 1 398 ? 25.662 38.911 1.074 1.00 16.41 ? 398 PRO A CG 1 ATOM 3123 C CD . PRO A 1 398 ? 26.249 37.826 1.966 1.00 15.49 ? 398 PRO A CD 1 ATOM 3124 N N . THR A 1 399 ? 27.703 37.934 -2.443 1.00 13.67 ? 399 THR A N 1 ATOM 3125 C CA . THR A 1 399 ? 28.618 38.645 -3.328 1.00 12.97 ? 399 THR A CA 1 ATOM 3126 C C . THR A 1 399 ? 27.843 39.868 -3.839 1.00 14.17 ? 399 THR A C 1 ATOM 3127 O O . THR A 1 399 ? 26.624 39.850 -3.983 1.00 14.59 ? 399 THR A O 1 ATOM 3128 C CB . THR A 1 399 ? 29.015 37.775 -4.507 1.00 13.61 ? 399 THR A CB 1 ATOM 3129 O OG1 . THR A 1 399 ? 27.820 37.343 -5.181 1.00 15.94 ? 399 THR A OG1 1 ATOM 3130 C CG2 . THR A 1 399 ? 29.820 36.564 -4.013 1.00 15.27 ? 399 THR A CG2 1 ATOM 3131 N N . LEU A 1 400 ? 28.578 40.945 -4.077 1.00 12.67 ? 400 LEU A N 1 ATOM 3132 C CA . LEU A 1 400 ? 27.977 42.184 -4.523 1.00 12.47 ? 400 LEU A CA 1 ATOM 3133 C C . LEU A 1 400 ? 28.888 42.932 -5.476 1.00 11.59 ? 400 LEU A C 1 ATOM 3134 O O . LEU A 1 400 ? 30.122 42.876 -5.364 1.00 12.51 ? 400 LEU A O 1 ATOM 3135 C CB . LEU A 1 400 ? 27.709 43.097 -3.298 1.00 13.24 ? 400 LEU A CB 1 ATOM 3136 C CG . LEU A 1 400 ? 27.031 44.473 -3.552 1.00 12.14 ? 400 LEU A CG 1 ATOM 3137 C CD1 . LEU A 1 400 ? 26.204 44.842 -2.280 1.00 13.93 ? 400 LEU A CD1 1 ATOM 3138 C CD2 . LEU A 1 400 ? 28.047 45.570 -3.848 1.00 12.47 ? 400 LEU A CD2 1 ATOM 3139 N N . SER A 1 401 ? 28.273 43.565 -6.487 1.00 11.68 ? 401 SER A N 1 ATOM 3140 C CA . SER A 1 401 ? 29.048 44.493 -7.326 1.00 12.39 ? 401 SER A CA 1 ATOM 3141 C C . SER A 1 401 ? 28.185 45.731 -7.530 1.00 12.46 ? 401 SER A C 1 ATOM 3142 O O . SER A 1 401 ? 26.974 45.718 -7.333 1.00 11.82 ? 401 SER A O 1 ATOM 3143 C CB . SER A 1 401 ? 29.415 43.924 -8.694 1.00 13.50 ? 401 SER A CB 1 ATOM 3144 O OG . SER A 1 401 ? 28.277 43.858 -9.572 1.00 13.14 ? 401 SER A OG 1 ATOM 3145 N N . GLY A 1 402 ? 28.851 46.822 -7.884 1.00 11.68 ? 402 GLY A N 1 ATOM 3146 C CA . GLY A 1 402 ? 28.154 48.074 -8.111 1.00 11.35 ? 402 GLY A CA 1 ATOM 3147 C C . GLY A 1 402 ? 28.784 49.173 -7.251 1.00 12.12 ? 402 GLY A C 1 ATOM 3148 O O . GLY A 1 402 ? 29.862 48.976 -6.627 1.00 13.89 ? 402 GLY A O 1 ATOM 3149 N N . ASP A 1 403 ? 28.141 50.325 -7.208 1.00 10.63 ? 403 ASP A N 1 ATOM 3150 C CA . ASP A 1 403 ? 28.651 51.442 -6.375 1.00 10.96 ? 403 ASP A CA 1 ATOM 3151 C C . ASP A 1 403 ? 27.533 51.915 -5.458 1.00 13.67 ? 403 ASP A C 1 ATOM 3152 O O . ASP A 1 403 ? 26.417 51.338 -5.441 1.00 12.69 ? 403 ASP A O 1 ATOM 3153 C CB . ASP A 1 403 ? 29.169 52.610 -7.237 1.00 11.54 ? 403 ASP A CB 1 ATOM 3154 C CG . ASP A 1 403 ? 28.047 53.379 -7.940 1.00 15.55 ? 403 ASP A CG 1 ATOM 3155 O OD1 . ASP A 1 403 ? 26.882 52.931 -7.981 1.00 16.21 ? 403 ASP A OD1 1 ATOM 3156 O OD2 . ASP A 1 403 ? 28.389 54.455 -8.454 1.00 16.87 ? 403 ASP A OD2 1 ATOM 3157 N N . PHE A 1 404 ? 27.835 52.922 -4.677 1.00 11.26 ? 404 PHE A N 1 ATOM 3158 C CA . PHE A 1 404 ? 26.891 53.491 -3.733 1.00 11.26 ? 404 PHE A CA 1 ATOM 3159 C C . PHE A 1 404 ? 26.767 55.001 -3.882 1.00 11.99 ? 404 PHE A C 1 ATOM 3160 O O . PHE A 1 404 ? 26.893 55.771 -2.917 1.00 12.16 ? 404 PHE A O 1 ATOM 3161 C CB . PHE A 1 404 ? 27.253 53.103 -2.283 1.00 11.37 ? 404 PHE A CB 1 ATOM 3162 C CG . PHE A 1 404 ? 27.207 51.617 -2.053 1.00 10.67 ? 404 PHE A CG 1 ATOM 3163 C CD1 . PHE A 1 404 ? 25.959 50.967 -1.929 1.00 11.92 ? 404 PHE A CD1 1 ATOM 3164 C CD2 . PHE A 1 404 ? 28.372 50.864 -2.042 1.00 11.85 ? 404 PHE A CD2 1 ATOM 3165 C CE1 . PHE A 1 404 ? 25.899 49.537 -1.796 1.00 11.57 ? 404 PHE A CE1 1 ATOM 3166 C CE2 . PHE A 1 404 ? 28.316 49.458 -1.906 1.00 12.96 ? 404 PHE A CE2 1 ATOM 3167 C CZ . PHE A 1 404 ? 27.069 48.801 -1.786 1.00 11.44 ? 404 PHE A CZ 1 ATOM 3168 N N . PHE A 1 405 ? 26.475 55.387 -5.121 1.00 12.79 ? 405 PHE A N 1 ATOM 3169 C CA . PHE A 1 405 ? 26.186 56.790 -5.451 1.00 10.07 ? 405 PHE A CA 1 ATOM 3170 C C . PHE A 1 405 ? 24.817 56.740 -6.132 1.00 12.14 ? 405 PHE A C 1 ATOM 3171 O O . PHE A 1 405 ? 24.489 55.767 -6.815 1.00 14.12 ? 405 PHE A O 1 ATOM 3172 C CB . PHE A 1 405 ? 27.210 57.366 -6.451 1.00 11.04 ? 405 PHE A CB 1 ATOM 3173 C CG . PHE A 1 405 ? 28.597 57.494 -5.886 1.00 12.60 ? 405 PHE A CG 1 ATOM 3174 C CD1 . PHE A 1 405 ? 28.836 58.302 -4.774 1.00 12.65 ? 405 PHE A CD1 1 ATOM 3175 C CD2 . PHE A 1 405 ? 29.643 56.806 -6.472 1.00 12.95 ? 405 PHE A CD2 1 ATOM 3176 C CE1 . PHE A 1 405 ? 30.155 58.427 -4.239 1.00 13.86 ? 405 PHE A CE1 1 ATOM 3177 C CE2 . PHE A 1 405 ? 30.948 56.903 -5.959 1.00 13.20 ? 405 PHE A CE2 1 ATOM 3178 C CZ . PHE A 1 405 ? 31.201 57.719 -4.836 1.00 12.35 ? 405 PHE A CZ 1 ATOM 3179 N N . THR A 1 406 ? 23.994 57.778 -6.001 1.00 12.64 ? 406 THR A N 1 ATOM 3180 C CA . THR A 1 406 ? 24.232 58.993 -5.241 1.00 11.77 ? 406 THR A CA 1 ATOM 3181 C C . THR A 1 406 ? 23.563 58.870 -3.890 1.00 13.49 ? 406 THR A C 1 ATOM 3182 O O . THR A 1 406 ? 22.421 58.438 -3.741 1.00 13.91 ? 406 THR A O 1 ATOM 3183 C CB . THR A 1 406 ? 23.689 60.189 -6.024 1.00 11.89 ? 406 THR A CB 1 ATOM 3184 O OG1 . THR A 1 406 ? 24.594 60.418 -7.104 1.00 13.39 ? 406 THR A OG1 1 ATOM 3185 C CG2 . THR A 1 406 ? 23.581 61.473 -5.178 1.00 13.40 ? 406 THR A CG2 1 ATOM 3186 N N . TYR A 1 407 ? 24.352 59.210 -2.877 1.00 12.27 ? 407 TYR A N 1 ATOM 3187 C CA . TYR A 1 407 ? 23.918 59.105 -1.510 1.00 12.18 ? 407 TYR A CA 1 ATOM 3188 C C . TYR A 1 407 ? 22.839 60.093 -1.111 1.00 13.69 ? 407 TYR A C 1 ATOM 3189 O O . TYR A 1 407 ? 22.861 61.233 -1.552 1.00 15.08 ? 407 TYR A O 1 ATOM 3190 C CB . TYR A 1 407 ? 25.144 59.376 -0.624 1.00 13.05 ? 407 TYR A CB 1 ATOM 3191 C CG . TYR A 1 407 ? 24.895 59.540 0.844 1.00 12.57 ? 407 TYR A CG 1 ATOM 3192 C CD1 . TYR A 1 407 ? 24.436 58.459 1.637 1.00 13.47 ? 407 TYR A CD1 1 ATOM 3193 C CD2 . TYR A 1 407 ? 25.215 60.724 1.481 1.00 12.27 ? 407 TYR A CD2 1 ATOM 3194 C CE1 . TYR A 1 407 ? 24.317 58.594 3.031 1.00 13.43 ? 407 TYR A CE1 1 ATOM 3195 C CE2 . TYR A 1 407 ? 25.117 60.870 2.862 1.00 12.83 ? 407 TYR A CE2 1 ATOM 3196 C CZ . TYR A 1 407 ? 24.677 59.807 3.633 1.00 13.67 ? 407 TYR A CZ 1 ATOM 3197 O OH . TYR A 1 407 ? 24.685 59.943 5.008 1.00 13.85 ? 407 TYR A OH 1 ATOM 3198 N N . ALA A 1 408 ? 21.870 59.625 -0.328 1.00 14.33 ? 408 ALA A N 1 ATOM 3199 C CA . ALA A 1 408 ? 20.890 60.531 0.303 1.00 15.10 ? 408 ALA A CA 1 ATOM 3200 C C . ALA A 1 408 ? 20.830 60.037 1.734 1.00 13.59 ? 408 ALA A C 1 ATOM 3201 O O . ALA A 1 408 ? 20.712 58.815 1.990 1.00 15.29 ? 408 ALA A O 1 ATOM 3202 C CB . ALA A 1 408 ? 19.475 60.432 -0.317 1.00 15.40 ? 408 ALA A CB 1 ATOM 3203 N N . ASP A 1 409 ? 20.940 60.970 2.683 1.00 13.63 ? 409 ASP A N 1 ATOM 3204 C CA . ASP A 1 409 ? 20.858 60.601 4.092 1.00 13.93 ? 409 ASP A CA 1 ATOM 3205 C C . ASP A 1 409 ? 19.443 60.666 4.640 1.00 14.94 ? 409 ASP A C 1 ATOM 3206 O O . ASP A 1 409 ? 19.159 60.031 5.679 1.00 16.04 ? 409 ASP A O 1 ATOM 3207 C CB . ASP A 1 409 ? 21.824 61.443 4.966 1.00 14.18 ? 409 ASP A CB 1 ATOM 3208 C CG . ASP A 1 409 ? 21.561 62.962 4.903 1.00 13.25 ? 409 ASP A CG 1 ATOM 3209 O OD1 . ASP A 1 409 ? 20.911 63.462 3.963 1.00 14.88 ? 409 ASP A OD1 1 ATOM 3210 O OD2 . ASP A 1 409 ? 22.088 63.675 5.801 1.00 16.25 ? 409 ASP A OD2 1 ATOM 3211 N N . ARG A 1 410 ? 18.550 61.381 3.948 1.00 14.31 ? 410 ARG A N 1 ATOM 3212 C CA . ARG A 1 410 ? 17.152 61.471 4.402 1.00 17.08 ? 410 ARG A CA 1 ATOM 3213 C C . ARG A 1 410 ? 16.334 62.116 3.316 1.00 18.27 ? 410 ARG A C 1 ATOM 3214 O O . ARG A 1 410 ? 16.885 62.855 2.483 1.00 17.55 ? 410 ARG A O 1 ATOM 3215 C CB . ARG A 1 410 ? 17.050 62.295 5.677 1.00 17.35 ? 410 ARG A CB 1 ATOM 3216 C CG . ARG A 1 410 ? 17.482 63.760 5.564 1.00 20.19 ? 410 ARG A CG 1 ATOM 3217 C CD . ARG A 1 410 ? 17.474 64.304 6.963 1.00 19.67 ? 410 ARG A CD 1 ATOM 3218 N NE . ARG A 1 410 ? 18.118 65.609 7.141 1.00 21.85 ? 410 ARG A NE 1 ATOM 3219 C CZ . ARG A 1 410 ? 17.549 66.788 6.893 1.00 23.79 ? 410 ARG A CZ 1 ATOM 3220 N NH1 . ARG A 1 410 ? 16.291 66.844 6.427 1.00 23.80 ? 410 ARG A NH1 1 ATOM 3221 N NH2 . ARG A 1 410 ? 18.230 67.908 7.127 1.00 23.68 ? 410 ARG A NH2 1 ATOM 3222 N N . SER A 1 411 ? 15.047 61.771 3.274 1.00 17.83 ? 411 SER A N 1 ATOM 3223 C CA . SER A 1 411 ? 14.085 62.289 2.298 1.00 18.24 ? 411 SER A CA 1 ATOM 3224 C C . SER A 1 411 ? 14.616 62.425 0.868 1.00 17.16 ? 411 SER A C 1 ATOM 3225 O O . SER A 1 411 ? 15.043 61.429 0.279 1.00 18.40 ? 411 SER A O 1 ATOM 3226 C CB A SER A 1 411 ? 13.466 63.609 2.812 0.50 21.37 ? 411 SER A CB 1 ATOM 3227 C CB B SER A 1 411 ? 13.768 63.870 2.857 0.50 21.86 ? 411 SER A CB 1 ATOM 3228 O OG A SER A 1 411 ? 14.436 64.551 3.247 0.50 22.93 ? 411 SER A OG 1 ATOM 3229 O OG B SER A 1 411 ? 12.657 64.400 2.169 0.50 23.64 ? 411 SER A OG 1 ATOM 3230 N N . ASP A 1 412 ? 14.577 63.630 0.295 1.00 16.03 ? 412 ASP A N 1 ATOM 3231 C CA . ASP A 1 412 ? 15.064 63.819 -1.075 1.00 15.67 ? 412 ASP A CA 1 ATOM 3232 C C . ASP A 1 412 ? 16.398 64.576 -1.036 1.00 14.85 ? 412 ASP A C 1 ATOM 3233 O O . ASP A 1 412 ? 16.802 65.136 -2.042 1.00 15.95 ? 412 ASP A O 1 ATOM 3234 C CB . ASP A 1 412 ? 14.065 64.659 -1.888 1.00 17.35 ? 412 ASP A CB 1 ATOM 3235 C CG . ASP A 1 412 ? 13.871 66.082 -1.297 1.00 16.31 ? 412 ASP A CG 1 ATOM 3236 O OD1 . ASP A 1 412 ? 14.401 66.417 -0.204 1.00 17.38 ? 412 ASP A OD1 1 ATOM 3237 O OD2 . ASP A 1 412 ? 13.173 66.898 -1.960 1.00 19.37 ? 412 ASP A OD2 1 ATOM 3238 N N . ASN A 1 413 ? 17.098 64.521 0.091 1.00 14.67 ? 413 ASN A N 1 ATOM 3239 C CA . ASN A 1 413 ? 18.362 65.250 0.240 1.00 15.52 ? 413 ASN A CA 1 ATOM 3240 C C . ASN A 1 413 ? 19.520 64.393 -0.327 1.00 13.77 ? 413 ASN A C 1 ATOM 3241 O O . ASN A 1 413 ? 20.218 63.706 0.436 1.00 14.45 ? 413 ASN A O 1 ATOM 3242 C CB . ASN A 1 413 ? 18.624 65.573 1.721 1.00 15.58 ? 413 ASN A CB 1 ATOM 3243 C CG . ASN A 1 413 ? 17.696 66.678 2.328 1.00 16.20 ? 413 ASN A CG 1 ATOM 3244 O OD1 . ASN A 1 413 ? 17.964 67.148 3.430 1.00 17.49 ? 413 ASN A OD1 1 ATOM 3245 N ND2 . ASN A 1 413 ? 16.633 67.087 1.617 1.00 14.87 ? 413 ASN A ND2 1 ATOM 3246 N N . TYR A 1 414 ? 19.691 64.460 -1.645 1.00 13.88 ? 414 TYR A N 1 ATOM 3247 C CA . TYR A 1 414 ? 20.755 63.734 -2.363 1.00 13.44 ? 414 TYR A CA 1 ATOM 3248 C C . TYR A 1 414 ? 21.995 64.621 -2.420 1.00 13.96 ? 414 TYR A C 1 ATOM 3249 O O . TYR A 1 414 ? 21.897 65.818 -2.738 1.00 14.75 ? 414 TYR A O 1 ATOM 3250 C CB . TYR A 1 414 ? 20.307 63.386 -3.781 1.00 13.21 ? 414 TYR A CB 1 ATOM 3251 C CG . TYR A 1 414 ? 19.295 62.257 -3.807 1.00 14.65 ? 414 TYR A CG 1 ATOM 3252 C CD1 . TYR A 1 414 ? 17.942 62.500 -3.568 1.00 16.35 ? 414 TYR A CD1 1 ATOM 3253 C CD2 . TYR A 1 414 ? 19.725 60.927 -4.011 1.00 14.29 ? 414 TYR A CD2 1 ATOM 3254 C CE1 . TYR A 1 414 ? 17.017 61.420 -3.511 1.00 15.28 ? 414 TYR A CE1 1 ATOM 3255 C CE2 . TYR A 1 414 ? 18.790 59.848 -3.979 1.00 14.79 ? 414 TYR A CE2 1 ATOM 3256 C CZ . TYR A 1 414 ? 17.470 60.129 -3.725 1.00 15.12 ? 414 TYR A CZ 1 ATOM 3257 O OH . TYR A 1 414 ? 16.595 59.054 -3.726 1.00 14.37 ? 414 TYR A OH 1 ATOM 3258 N N . TRP A 1 415 ? 23.141 64.009 -2.122 1.00 13.37 ? 415 TRP A N 1 ATOM 3259 C CA . TRP A 1 415 ? 24.397 64.735 -2.024 1.00 12.68 ? 415 TRP A CA 1 ATOM 3260 C C . TRP A 1 415 ? 25.129 64.789 -3.351 1.00 14.74 ? 415 TRP A C 1 ATOM 3261 O O . TRP A 1 415 ? 26.235 64.284 -3.462 1.00 15.78 ? 415 TRP A O 1 ATOM 3262 C CB . TRP A 1 415 ? 25.279 64.053 -0.975 1.00 13.27 ? 415 TRP A CB 1 ATOM 3263 C CG . TRP A 1 415 ? 24.709 64.119 0.458 1.00 12.30 ? 415 TRP A CG 1 ATOM 3264 C CD1 . TRP A 1 415 ? 23.408 63.841 0.869 1.00 12.74 ? 415 TRP A CD1 1 ATOM 3265 C CD2 . TRP A 1 415 ? 25.460 64.402 1.645 1.00 12.75 ? 415 TRP A CD2 1 ATOM 3266 N NE1 . TRP A 1 415 ? 23.330 63.942 2.246 1.00 12.67 ? 415 TRP A NE1 1 ATOM 3267 C CE2 . TRP A 1 415 ? 24.566 64.278 2.751 1.00 12.14 ? 415 TRP A CE2 1 ATOM 3268 C CE3 . TRP A 1 415 ? 26.813 64.740 1.888 1.00 13.91 ? 415 TRP A CE3 1 ATOM 3269 C CZ2 . TRP A 1 415 ? 24.976 64.483 4.066 1.00 13.19 ? 415 TRP A CZ2 1 ATOM 3270 C CZ3 . TRP A 1 415 ? 27.217 64.937 3.168 1.00 12.46 ? 415 TRP A CZ3 1 ATOM 3271 C CH2 . TRP A 1 415 ? 26.309 64.810 4.267 1.00 13.54 ? 415 TRP A CH2 1 ATOM 3272 N N . SER A 1 416 ? 24.475 65.337 -4.363 1.00 11.68 ? 416 SER A N 1 ATOM 3273 C CA . SER A 1 416 ? 25.137 65.461 -5.659 1.00 13.69 ? 416 SER A CA 1 ATOM 3274 C C . SER A 1 416 ? 25.710 66.869 -5.879 1.00 12.26 ? 416 SER A C 1 ATOM 3275 O O . SER A 1 416 ? 26.389 67.087 -6.872 1.00 12.16 ? 416 SER A O 1 ATOM 3276 C CB . SER A 1 416 ? 24.195 65.050 -6.803 1.00 13.23 ? 416 SER A CB 1 ATOM 3277 O OG . SER A 1 416 ? 22.899 65.627 -6.630 1.00 13.59 ? 416 SER A OG 1 ATOM 3278 N N . GLY A 1 417 ? 25.472 67.803 -4.958 1.00 12.07 ? 417 GLY A N 1 ATOM 3279 C CA . GLY A 1 417 ? 26.035 69.138 -5.135 1.00 13.82 ? 417 GLY A CA 1 ATOM 3280 C C . GLY A 1 417 ? 27.563 69.138 -5.060 1.00 11.84 ? 417 GLY A C 1 ATOM 3281 O O . GLY A 1 417 ? 28.236 69.858 -5.817 1.00 12.56 ? 417 GLY A O 1 ATOM 3282 N N . TYR A 1 418 ? 28.132 68.296 -4.187 1.00 11.43 ? 418 TYR A N 1 ATOM 3283 C CA . TYR A 1 418 ? 29.593 68.319 -4.009 1.00 12.40 ? 418 TYR A CA 1 ATOM 3284 C C . TYR A 1 418 ? 30.351 67.697 -5.162 1.00 12.59 ? 418 TYR A C 1 ATOM 3285 O O . TYR A 1 418 ? 31.571 67.695 -5.198 1.00 12.35 ? 418 TYR A O 1 ATOM 3286 C CB . TYR A 1 418 ? 30.001 67.681 -2.673 1.00 10.58 ? 418 TYR A CB 1 ATOM 3287 C CG . TYR A 1 418 ? 30.085 66.162 -2.697 1.00 12.12 ? 418 TYR A CG 1 ATOM 3288 C CD1 . TYR A 1 418 ? 28.930 65.350 -2.508 1.00 11.22 ? 418 TYR A CD1 1 ATOM 3289 C CD2 . TYR A 1 418 ? 31.323 65.532 -2.911 1.00 12.01 ? 418 TYR A CD2 1 ATOM 3290 C CE1 . TYR A 1 418 ? 29.031 63.940 -2.531 1.00 11.07 ? 418 TYR A CE1 1 ATOM 3291 C CE2 . TYR A 1 418 ? 31.443 64.173 -2.931 1.00 11.18 ? 418 TYR A CE2 1 ATOM 3292 C CZ . TYR A 1 418 ? 30.301 63.364 -2.738 1.00 9.89 ? 418 TYR A CZ 1 ATOM 3293 O OH . TYR A 1 418 ? 30.510 61.992 -2.724 1.00 11.87 ? 418 TYR A OH 1 ATOM 3294 N N . TYR A 1 419 ? 29.618 67.161 -6.127 1.00 10.83 ? 419 TYR A N 1 ATOM 3295 C CA . TYR A 1 419 ? 30.288 66.687 -7.342 1.00 10.78 ? 419 TYR A CA 1 ATOM 3296 C C . TYR A 1 419 ? 30.797 67.899 -8.130 1.00 11.33 ? 419 TYR A C 1 ATOM 3297 O O . TYR A 1 419 ? 31.621 67.725 -9.033 1.00 11.80 ? 419 TYR A O 1 ATOM 3298 C CB . TYR A 1 419 ? 29.326 65.904 -8.240 1.00 10.12 ? 419 TYR A CB 1 ATOM 3299 C CG . TYR A 1 419 ? 28.672 64.712 -7.592 1.00 10.83 ? 419 TYR A CG 1 ATOM 3300 C CD1 . TYR A 1 419 ? 29.264 64.035 -6.486 1.00 11.57 ? 419 TYR A CD1 1 ATOM 3301 C CD2 . TYR A 1 419 ? 27.495 64.193 -8.142 1.00 10.94 ? 419 TYR A CD2 1 ATOM 3302 C CE1 . TYR A 1 419 ? 28.699 62.865 -5.943 1.00 11.02 ? 419 TYR A CE1 1 ATOM 3303 C CE2 . TYR A 1 419 ? 26.907 63.037 -7.605 1.00 11.92 ? 419 TYR A CE2 1 ATOM 3304 C CZ . TYR A 1 419 ? 27.522 62.378 -6.511 1.00 11.36 ? 419 TYR A CZ 1 ATOM 3305 O OH . TYR A 1 419 ? 26.911 61.255 -6.008 1.00 12.24 ? 419 TYR A OH 1 ATOM 3306 N N . THR A 1 420 ? 30.307 69.108 -7.804 1.00 11.59 ? 420 THR A N 1 ATOM 3307 C CA . THR A 1 420 ? 30.691 70.315 -8.518 1.00 12.02 ? 420 THR A CA 1 ATOM 3308 C C . THR A 1 420 ? 31.235 71.426 -7.645 1.00 12.18 ? 420 THR A C 1 ATOM 3309 O O . THR A 1 420 ? 32.015 72.239 -8.118 1.00 12.94 ? 420 THR A O 1 ATOM 3310 C CB . THR A 1 420 ? 29.459 70.836 -9.296 1.00 11.68 ? 420 THR A CB 1 ATOM 3311 O OG1 . THR A 1 420 ? 29.016 69.802 -10.172 1.00 13.08 ? 420 THR A OG1 1 ATOM 3312 C CG2 . THR A 1 420 ? 29.736 72.048 -10.161 1.00 15.43 ? 420 THR A CG2 1 ATOM 3313 N N . SER A 1 421 ? 30.864 71.481 -6.371 1.00 11.27 ? 421 SER A N 1 ATOM 3314 C CA . SER A 1 421 ? 31.284 72.585 -5.525 1.00 12.89 ? 421 SER A CA 1 ATOM 3315 C C . SER A 1 421 ? 32.765 72.902 -5.574 1.00 13.32 ? 421 SER A C 1 ATOM 3316 O O . SER A 1 421 ? 33.617 72.007 -5.512 1.00 12.19 ? 421 SER A O 1 ATOM 3317 C CB . SER A 1 421 ? 30.905 72.298 -4.062 1.00 12.81 ? 421 SER A CB 1 ATOM 3318 O OG . SER A 1 421 ? 29.516 72.094 -3.952 1.00 13.42 ? 421 SER A OG 1 ATOM 3319 N N . ARG A 1 422 ? 33.061 74.207 -5.623 1.00 12.50 ? 422 ARG A N 1 ATOM 3320 C CA . ARG A 1 422 ? 34.459 74.716 -5.698 1.00 12.73 ? 422 ARG A CA 1 ATOM 3321 C C . ARG A 1 422 ? 35.187 74.068 -6.872 1.00 12.94 ? 422 ARG A C 1 ATOM 3322 O O . ARG A 1 422 ? 36.205 73.374 -6.731 1.00 12.90 ? 422 ARG A O 1 ATOM 3323 C CB . ARG A 1 422 ? 35.210 74.483 -4.375 1.00 13.08 ? 422 ARG A CB 1 ATOM 3324 C CG . ARG A 1 422 ? 34.955 75.569 -3.275 1.00 14.88 ? 422 ARG A CG 1 ATOM 3325 C CD . ARG A 1 422 ? 33.503 75.683 -2.816 1.00 12.16 ? 422 ARG A CD 1 ATOM 3326 N NE . ARG A 1 422 ? 33.447 76.688 -1.744 1.00 14.00 ? 422 ARG A NE 1 ATOM 3327 C CZ . ARG A 1 422 ? 33.500 76.388 -0.449 1.00 14.14 ? 422 ARG A CZ 1 ATOM 3328 N NH1 . ARG A 1 422 ? 33.540 75.140 -0.023 1.00 14.58 ? 422 ARG A NH1 1 ATOM 3329 N NH2 . ARG A 1 422 ? 33.711 77.348 0.456 1.00 13.81 ? 422 ARG A NH2 1 ATOM 3330 N N . PRO A 1 423 ? 34.657 74.275 -8.068 1.00 12.14 ? 423 PRO A N 1 ATOM 3331 C CA . PRO A 1 423 ? 35.276 73.662 -9.244 1.00 12.23 ? 423 PRO A CA 1 ATOM 3332 C C . PRO A 1 423 ? 36.677 74.121 -9.586 1.00 12.13 ? 423 PRO A C 1 ATOM 3333 O O . PRO A 1 423 ? 37.419 73.387 -10.247 1.00 12.94 ? 423 PRO A O 1 ATOM 3334 C CB . PRO A 1 423 ? 34.247 73.941 -10.361 1.00 10.70 ? 423 PRO A CB 1 ATOM 3335 C CG . PRO A 1 423 ? 33.684 75.279 -9.943 1.00 12.63 ? 423 PRO A CG 1 ATOM 3336 C CD . PRO A 1 423 ? 33.536 75.160 -8.425 1.00 12.58 ? 423 PRO A CD 1 ATOM 3337 N N . TYR A 1 424 ? 37.063 75.318 -9.176 1.00 12.28 ? 424 TYR A N 1 ATOM 3338 C CA . TYR A 1 424 ? 38.441 75.746 -9.419 1.00 11.98 ? 424 TYR A CA 1 ATOM 3339 C C . TYR A 1 424 ? 39.423 74.754 -8.795 1.00 12.17 ? 424 TYR A C 1 ATOM 3340 O O . TYR A 1 424 ? 40.377 74.324 -9.441 1.00 11.73 ? 424 TYR A O 1 ATOM 3341 C CB . TYR A 1 424 ? 38.655 77.109 -8.773 1.00 12.91 ? 424 TYR A CB 1 ATOM 3342 C CG . TYR A 1 424 ? 40.029 77.658 -9.033 1.00 13.20 ? 424 TYR A CG 1 ATOM 3343 C CD1 . TYR A 1 424 ? 41.108 77.391 -8.159 1.00 12.03 ? 424 TYR A CD1 1 ATOM 3344 C CD2 . TYR A 1 424 ? 40.252 78.458 -10.143 1.00 14.78 ? 424 TYR A CD2 1 ATOM 3345 C CE1 . TYR A 1 424 ? 42.377 77.949 -8.422 1.00 15.77 ? 424 TYR A CE1 1 ATOM 3346 C CE2 . TYR A 1 424 ? 41.475 78.972 -10.395 1.00 16.49 ? 424 TYR A CE2 1 ATOM 3347 C CZ . TYR A 1 424 ? 42.540 78.726 -9.536 1.00 15.07 ? 424 TYR A CZ 1 ATOM 3348 O OH . TYR A 1 424 ? 43.760 79.316 -9.877 1.00 21.31 ? 424 TYR A OH 1 ATOM 3349 N N . HIS A 1 425 ? 39.141 74.335 -7.562 1.00 12.12 ? 425 HIS A N 1 ATOM 3350 C CA . HIS A 1 425 ? 40.075 73.423 -6.889 1.00 12.16 ? 425 HIS A CA 1 ATOM 3351 C C . HIS A 1 425 ? 39.950 72.007 -7.368 1.00 11.18 ? 425 HIS A C 1 ATOM 3352 O O . HIS A 1 425 ? 40.921 71.238 -7.311 1.00 10.29 ? 425 HIS A O 1 ATOM 3353 C CB . HIS A 1 425 ? 39.862 73.548 -5.378 1.00 11.93 ? 425 HIS A CB 1 ATOM 3354 C CG . HIS A 1 425 ? 39.833 74.970 -4.944 1.00 12.94 ? 425 HIS A CG 1 ATOM 3355 N ND1 . HIS A 1 425 ? 40.973 75.719 -4.700 1.00 17.52 ? 425 HIS A ND1 1 ATOM 3356 C CD2 . HIS A 1 425 ? 38.794 75.831 -4.924 1.00 12.67 ? 425 HIS A CD2 1 ATOM 3357 C CE1 . HIS A 1 425 ? 40.618 76.984 -4.535 1.00 12.55 ? 425 HIS A CE1 1 ATOM 3358 N NE2 . HIS A 1 425 ? 39.307 77.074 -4.668 1.00 18.09 ? 425 HIS A NE2 1 ATOM 3359 N N . LYS A 1 426 ? 38.748 71.631 -7.838 1.00 11.97 ? 426 LYS A N 1 ATOM 3360 C CA . LYS A 1 426 ? 38.602 70.320 -8.463 1.00 11.37 ? 426 LYS A CA 1 ATOM 3361 C C . LYS A 1 426 ? 39.517 70.251 -9.711 1.00 11.02 ? 426 LYS A C 1 ATOM 3362 O O . LYS A 1 426 ? 40.148 69.219 -9.975 1.00 11.43 ? 426 LYS A O 1 ATOM 3363 C CB . LYS A 1 426 ? 37.127 70.081 -8.871 1.00 12.23 ? 426 LYS A CB 1 ATOM 3364 C CG . LYS A 1 426 ? 36.251 69.702 -7.704 1.00 11.08 ? 426 LYS A CG 1 ATOM 3365 C CD . LYS A 1 426 ? 34.753 69.775 -8.075 1.00 12.62 ? 426 LYS A CD 1 ATOM 3366 C CE . LYS A 1 426 ? 33.876 68.876 -7.196 1.00 12.42 ? 426 LYS A CE 1 ATOM 3367 N NZ . LYS A 1 426 ? 33.855 69.329 -5.741 1.00 13.09 ? 426 LYS A NZ 1 ATOM 3368 N N . ARG A 1 427 ? 39.547 71.334 -10.508 1.00 10.70 ? 427 ARG A N 1 ATOM 3369 C CA . ARG A 1 427 ? 40.406 71.315 -11.678 1.00 11.15 ? 427 ARG A CA 1 ATOM 3370 C C . ARG A 1 427 ? 41.879 71.334 -11.237 1.00 12.63 ? 427 ARG A C 1 ATOM 3371 O O . ARG A 1 427 ? 42.712 70.643 -11.786 1.00 11.92 ? 427 ARG A O 1 ATOM 3372 C CB . ARG A 1 427 ? 40.061 72.542 -12.526 1.00 11.34 ? 427 ARG A CB 1 ATOM 3373 C CG . ARG A 1 427 ? 40.994 72.783 -13.707 1.00 11.17 ? 427 ARG A CG 1 ATOM 3374 C CD . ARG A 1 427 ? 41.120 71.655 -14.709 1.00 13.43 ? 427 ARG A CD 1 ATOM 3375 N NE . ARG A 1 427 ? 42.156 72.063 -15.670 1.00 15.45 ? 427 ARG A NE 1 ATOM 3376 C CZ . ARG A 1 427 ? 42.974 71.236 -16.274 1.00 16.44 ? 427 ARG A CZ 1 ATOM 3377 N NH1 . ARG A 1 427 ? 42.930 69.929 -16.079 1.00 15.25 ? 427 ARG A NH1 1 ATOM 3378 N NH2 . ARG A 1 427 ? 43.902 71.750 -17.088 1.00 16.44 ? 427 ARG A NH2 1 ATOM 3379 N N . MET A 1 428 ? 42.192 72.134 -10.221 1.00 10.44 ? 428 MET A N 1 ATOM 3380 C CA . MET A 1 428 ? 43.559 72.196 -9.725 1.00 11.45 ? 428 MET A CA 1 ATOM 3381 C C . MET A 1 428 ? 44.057 70.811 -9.265 1.00 10.92 ? 428 MET A C 1 ATOM 3382 O O . MET A 1 428 ? 45.233 70.454 -9.491 1.00 11.18 ? 428 MET A O 1 ATOM 3383 C CB . MET A 1 428 ? 43.650 73.153 -8.554 1.00 13.00 ? 428 MET A CB 1 ATOM 3384 C CG . MET A 1 428 ? 45.094 73.514 -8.172 1.00 12.25 ? 428 MET A CG 1 ATOM 3385 S SD . MET A 1 428 ? 44.994 74.853 -6.923 1.00 15.03 ? 428 MET A SD 1 ATOM 3386 C CE . MET A 1 428 ? 46.726 75.410 -6.858 1.00 15.26 ? 428 MET A CE 1 ATOM 3387 N N . ASP A 1 429 ? 43.159 70.025 -8.660 1.00 11.08 ? 429 ASP A N 1 ATOM 3388 C CA . ASP A 1 429 ? 43.524 68.654 -8.268 1.00 10.79 ? 429 ASP A CA 1 ATOM 3389 C C . ASP A 1 429 ? 44.108 67.839 -9.442 1.00 9.80 ? 429 ASP A C 1 ATOM 3390 O O . ASP A 1 429 ? 45.096 67.123 -9.307 1.00 11.30 ? 429 ASP A O 1 ATOM 3391 C CB . ASP A 1 429 ? 42.263 67.933 -7.769 1.00 11.31 ? 429 ASP A CB 1 ATOM 3392 C CG . ASP A 1 429 ? 42.526 66.472 -7.470 1.00 11.55 ? 429 ASP A CG 1 ATOM 3393 O OD1 . ASP A 1 429 ? 43.066 66.257 -6.369 1.00 12.67 ? 429 ASP A OD1 1 ATOM 3394 O OD2 . ASP A 1 429 ? 42.227 65.585 -8.316 1.00 11.61 ? 429 ASP A OD2 1 ATOM 3395 N N . ARG A 1 430 ? 43.468 67.934 -10.618 1.00 10.79 ? 430 ARG A N 1 ATOM 3396 C CA . ARG A 1 430 ? 43.906 67.147 -11.749 1.00 10.33 ? 430 ARG A CA 1 ATOM 3397 C C . ARG A 1 430 ? 45.202 67.684 -12.298 1.00 10.57 ? 430 ARG A C 1 ATOM 3398 O O . ARG A 1 430 ? 46.032 66.901 -12.786 1.00 11.35 ? 430 ARG A O 1 ATOM 3399 C CB . ARG A 1 430 ? 42.816 67.184 -12.840 1.00 11.14 ? 430 ARG A CB 1 ATOM 3400 C CG . ARG A 1 430 ? 41.532 66.441 -12.441 1.00 11.56 ? 430 ARG A CG 1 ATOM 3401 C CD . ARG A 1 430 ? 41.814 65.024 -11.976 1.00 10.05 ? 430 ARG A CD 1 ATOM 3402 N NE . ARG A 1 430 ? 40.572 64.273 -12.008 1.00 11.16 ? 430 ARG A NE 1 ATOM 3403 C CZ . ARG A 1 430 ? 39.861 63.931 -10.937 1.00 11.09 ? 430 ARG A CZ 1 ATOM 3404 N NH1 . ARG A 1 430 ? 40.271 64.264 -9.712 1.00 10.54 ? 430 ARG A NH1 1 ATOM 3405 N NH2 . ARG A 1 430 ? 38.727 63.236 -11.068 1.00 11.82 ? 430 ARG A NH2 1 ATOM 3406 N N . VAL A 1 431 ? 45.389 69.007 -12.269 1.00 11.11 ? 431 VAL A N 1 ATOM 3407 C CA . VAL A 1 431 ? 46.663 69.579 -12.728 1.00 10.44 ? 431 VAL A CA 1 ATOM 3408 C C . VAL A 1 431 ? 47.819 69.082 -11.826 1.00 12.39 ? 431 VAL A C 1 ATOM 3409 O O . VAL A 1 431 ? 48.848 68.600 -12.296 1.00 12.99 ? 431 VAL A O 1 ATOM 3410 C CB . VAL A 1 431 ? 46.549 71.103 -12.709 1.00 11.26 ? 431 VAL A CB 1 ATOM 3411 C CG1 . VAL A 1 431 ? 47.909 71.743 -13.055 1.00 13.39 ? 431 VAL A CG1 1 ATOM 3412 C CG2 . VAL A 1 431 ? 45.459 71.556 -13.751 1.00 11.69 ? 431 VAL A CG2 1 ATOM 3413 N N . LEU A 1 432 ? 47.617 69.175 -10.520 1.00 10.68 ? 432 LEU A N 1 ATOM 3414 C CA . LEU A 1 432 ? 48.671 68.761 -9.595 1.00 11.41 ? 432 LEU A CA 1 ATOM 3415 C C . LEU A 1 432 ? 48.861 67.249 -9.670 1.00 11.18 ? 432 LEU A C 1 ATOM 3416 O O . LEU A 1 432 ? 50.002 66.760 -9.537 1.00 11.78 ? 432 LEU A O 1 ATOM 3417 C CB . LEU A 1 432 ? 48.330 69.206 -8.176 1.00 12.13 ? 432 LEU A CB 1 ATOM 3418 C CG . LEU A 1 432 ? 49.367 68.847 -7.084 1.00 13.32 ? 432 LEU A CG 1 ATOM 3419 C CD1 . LEU A 1 432 ? 50.782 69.379 -7.431 1.00 12.29 ? 432 LEU A CD1 1 ATOM 3420 C CD2 . LEU A 1 432 ? 48.886 69.449 -5.751 1.00 12.18 ? 432 LEU A CD2 1 ATOM 3421 N N . MET A 1 433 ? 47.769 66.480 -9.892 1.00 9.80 ? 433 MET A N 1 ATOM 3422 C CA . MET A 1 433 ? 47.936 65.048 -10.063 1.00 10.56 ? 433 MET A CA 1 ATOM 3423 C C . MET A 1 433 ? 48.997 64.746 -11.128 1.00 10.69 ? 433 MET A C 1 ATOM 3424 O O . MET A 1 433 ? 49.866 63.883 -10.956 1.00 10.88 ? 433 MET A O 1 ATOM 3425 C CB . MET A 1 433 ? 46.616 64.453 -10.524 1.00 10.94 ? 433 MET A CB 1 ATOM 3426 C CG . MET A 1 433 ? 46.690 62.978 -10.786 1.00 10.45 ? 433 MET A CG 1 ATOM 3427 S SD . MET A 1 433 ? 45.142 62.284 -11.497 1.00 13.25 ? 433 MET A SD 1 ATOM 3428 C CE . MET A 1 433 ? 45.276 62.957 -13.148 1.00 15.16 ? 433 MET A CE 1 ATOM 3429 N N . HIS A 1 434 ? 48.878 65.418 -12.254 1.00 10.65 ? 434 HIS A N 1 ATOM 3430 C CA . HIS A 1 434 ? 49.801 65.192 -13.340 1.00 11.26 ? 434 HIS A CA 1 ATOM 3431 C C . HIS A 1 434 ? 51.198 65.727 -13.048 1.00 12.21 ? 434 HIS A C 1 ATOM 3432 O O . HIS A 1 434 ? 52.192 65.078 -13.405 1.00 11.66 ? 434 HIS A O 1 ATOM 3433 C CB . HIS A 1 434 ? 49.274 65.880 -14.590 1.00 12.43 ? 434 HIS A CB 1 ATOM 3434 C CG . HIS A 1 434 ? 50.246 65.818 -15.729 1.00 10.25 ? 434 HIS A CG 1 ATOM 3435 N ND1 . HIS A 1 434 ? 51.053 66.884 -16.101 1.00 14.24 ? 434 HIS A ND1 1 ATOM 3436 C CD2 . HIS A 1 434 ? 50.653 64.751 -16.446 1.00 10.04 ? 434 HIS A CD2 1 ATOM 3437 C CE1 . HIS A 1 434 ? 51.919 66.456 -17.017 1.00 10.27 ? 434 HIS A CE1 1 ATOM 3438 N NE2 . HIS A 1 434 ? 51.698 65.172 -17.227 1.00 13.72 ? 434 HIS A NE2 1 ATOM 3439 N N . TYR A 1 435 ? 51.282 66.884 -12.400 1.00 11.13 ? 435 TYR A N 1 ATOM 3440 C CA . TYR A 1 435 ? 52.596 67.453 -12.084 1.00 11.92 ? 435 TYR A CA 1 ATOM 3441 C C . TYR A 1 435 ? 53.351 66.535 -11.114 1.00 11.82 ? 435 TYR A C 1 ATOM 3442 O O . TYR A 1 435 ? 54.553 66.366 -11.248 1.00 12.81 ? 435 TYR A O 1 ATOM 3443 C CB A TYR A 1 435 ? 52.483 68.862 -11.449 0.50 12.89 ? 435 TYR A CB 1 ATOM 3444 C CB B TYR A 1 435 ? 52.573 68.904 -11.771 0.50 12.29 ? 435 TYR A CB 1 ATOM 3445 C CG A TYR A 1 435 ? 52.402 70.001 -12.436 0.50 16.52 ? 435 TYR A CG 1 ATOM 3446 C CG B TYR A 1 435 ? 52.454 69.754 -13.024 0.50 14.04 ? 435 TYR A CG 1 ATOM 3447 C CD1 A TYR A 1 435 ? 51.443 70.010 -13.444 0.50 14.79 ? 435 TYR A CD1 1 ATOM 3448 C CD1 B TYR A 1 435 ? 53.465 69.741 -13.993 0.50 17.83 ? 435 TYR A CD1 1 ATOM 3449 C CD2 A TYR A 1 435 ? 53.245 71.102 -12.317 0.50 19.01 ? 435 TYR A CD2 1 ATOM 3450 C CD2 B TYR A 1 435 ? 51.336 70.551 -13.255 0.50 15.52 ? 435 TYR A CD2 1 ATOM 3451 C CE1 A TYR A 1 435 ? 51.318 71.092 -14.310 0.50 17.17 ? 435 TYR A CE1 1 ATOM 3452 C CE1 B TYR A 1 435 ? 53.363 70.509 -15.161 0.50 19.10 ? 435 TYR A CE1 1 ATOM 3453 C CE2 A TYR A 1 435 ? 53.132 72.190 -13.179 0.50 19.33 ? 435 TYR A CE2 1 ATOM 3454 C CE2 B TYR A 1 435 ? 51.229 71.321 -14.415 0.50 16.20 ? 435 TYR A CE2 1 ATOM 3455 C CZ A TYR A 1 435 ? 52.166 72.175 -14.172 0.50 17.45 ? 435 TYR A CZ 1 ATOM 3456 C CZ B TYR A 1 435 ? 52.247 71.297 -15.362 0.50 18.57 ? 435 TYR A CZ 1 ATOM 3457 O OH A TYR A 1 435 ? 52.063 73.237 -15.043 0.50 21.96 ? 435 TYR A OH 1 ATOM 3458 O OH B TYR A 1 435 ? 52.159 72.083 -16.500 0.50 17.39 ? 435 TYR A OH 1 ATOM 3459 N N . VAL A 1 436 ? 52.648 65.948 -10.149 1.00 10.65 ? 436 VAL A N 1 ATOM 3460 C CA . VAL A 1 436 ? 53.318 65.058 -9.203 1.00 11.14 ? 436 VAL A CA 1 ATOM 3461 C C . VAL A 1 436 ? 53.822 63.840 -9.999 1.00 11.45 ? 436 VAL A C 1 ATOM 3462 O O . VAL A 1 436 ? 54.969 63.401 -9.807 1.00 11.13 ? 436 VAL A O 1 ATOM 3463 C CB . VAL A 1 436 ? 52.336 64.614 -8.064 1.00 12.15 ? 436 VAL A CB 1 ATOM 3464 C CG1 . VAL A 1 436 ? 52.854 63.366 -7.304 1.00 11.81 ? 436 VAL A CG1 1 ATOM 3465 C CG2 . VAL A 1 436 ? 52.176 65.770 -7.079 1.00 11.78 ? 436 VAL A CG2 1 ATOM 3466 N N . ARG A 1 437 ? 52.982 63.249 -10.864 1.00 11.29 ? 437 ARG A N 1 ATOM 3467 C CA . ARG A 1 437 ? 53.467 62.107 -11.621 1.00 11.15 ? 437 ARG A CA 1 ATOM 3468 C C . ARG A 1 437 ? 54.703 62.474 -12.441 1.00 11.98 ? 437 ARG A C 1 ATOM 3469 O O . ARG A 1 437 ? 55.690 61.719 -12.474 1.00 12.22 ? 437 ARG A O 1 ATOM 3470 C CB . ARG A 1 437 ? 52.380 61.563 -12.550 1.00 11.82 ? 437 ARG A CB 1 ATOM 3471 C CG . ARG A 1 437 ? 52.915 60.606 -13.610 1.00 12.77 ? 437 ARG A CG 1 ATOM 3472 C CD . ARG A 1 437 ? 51.779 60.101 -14.470 1.00 11.86 ? 437 ARG A CD 1 ATOM 3473 N NE . ARG A 1 437 ? 52.269 59.423 -15.679 1.00 10.70 ? 437 ARG A NE 1 ATOM 3474 C CZ . ARG A 1 437 ? 51.520 58.592 -16.404 1.00 12.44 ? 437 ARG A CZ 1 ATOM 3475 N NH1 . ARG A 1 437 ? 50.253 58.295 -16.066 1.00 13.92 ? 437 ARG A NH1 1 ATOM 3476 N NH2 . ARG A 1 437 ? 52.082 58.026 -17.461 1.00 13.70 ? 437 ARG A NH2 1 ATOM 3477 N N . ALA A 1 438 ? 54.624 63.603 -13.162 1.00 11.22 ? 438 ALA A N 1 ATOM 3478 C CA . ALA A 1 438 ? 55.740 64.018 -14.025 1.00 10.83 ? 438 ALA A CA 1 ATOM 3479 C C . ALA A 1 438 ? 57.032 64.336 -13.231 1.00 11.47 ? 438 ALA A C 1 ATOM 3480 O O . ALA A 1 438 ? 58.135 63.957 -13.682 1.00 11.85 ? 438 ALA A O 1 ATOM 3481 C CB . ALA A 1 438 ? 55.339 65.188 -14.875 1.00 11.72 ? 438 ALA A CB 1 ATOM 3482 N N . ALA A 1 439 ? 56.900 64.969 -12.065 1.00 11.54 ? 439 ALA A N 1 ATOM 3483 C CA . ALA A 1 439 ? 58.054 65.282 -11.238 1.00 11.77 ? 439 ALA A CA 1 ATOM 3484 C C . ALA A 1 439 ? 58.680 63.990 -10.695 1.00 12.06 ? 439 ALA A C 1 ATOM 3485 O O . ALA A 1 439 ? 59.924 63.832 -10.699 1.00 12.39 ? 439 ALA A O 1 ATOM 3486 C CB . ALA A 1 439 ? 57.630 66.156 -10.119 1.00 11.93 ? 439 ALA A CB 1 ATOM 3487 N N . GLU A 1 440 ? 57.840 63.061 -10.228 1.00 10.09 ? 440 GLU A N 1 ATOM 3488 C CA . GLU A 1 440 ? 58.421 61.817 -9.716 1.00 10.27 ? 440 GLU A CA 1 ATOM 3489 C C . GLU A 1 440 ? 59.077 61.014 -10.834 1.00 11.05 ? 440 GLU A C 1 ATOM 3490 O O . GLU A 1 440 ? 60.117 60.405 -10.617 1.00 12.86 ? 440 GLU A O 1 ATOM 3491 C CB . GLU A 1 440 ? 57.368 60.951 -9.022 1.00 11.16 ? 440 GLU A CB 1 ATOM 3492 C CG . GLU A 1 440 ? 56.832 61.614 -7.765 1.00 13.12 ? 440 GLU A CG 1 ATOM 3493 C CD . GLU A 1 440 ? 56.134 60.634 -6.826 1.00 16.61 ? 440 GLU A CD 1 ATOM 3494 O OE1 . GLU A 1 440 ? 55.030 60.165 -7.104 1.00 15.63 ? 440 GLU A OE1 1 ATOM 3495 O OE2 . GLU A 1 440 ? 56.749 60.304 -5.799 1.00 16.48 ? 440 GLU A OE2 1 ATOM 3496 N N . MET A 1 441 ? 58.466 60.983 -12.014 1.00 11.96 ? 441 MET A N 1 ATOM 3497 C CA . MET A 1 441 ? 59.044 60.215 -13.095 1.00 11.53 ? 441 MET A CA 1 ATOM 3498 C C . MET A 1 441 ? 60.329 60.859 -13.643 1.00 12.58 ? 441 MET A C 1 ATOM 3499 O O . MET A 1 441 ? 61.348 60.179 -13.774 1.00 13.08 ? 441 MET A O 1 ATOM 3500 C CB . MET A 1 441 ? 57.998 60.100 -14.221 1.00 11.73 ? 441 MET A CB 1 ATOM 3501 C CG . MET A 1 441 ? 58.495 59.323 -15.431 1.00 10.89 ? 441 MET A CG 1 ATOM 3502 S SD . MET A 1 441 ? 57.220 59.098 -16.719 1.00 12.31 ? 441 MET A SD 1 ATOM 3503 C CE . MET A 1 441 ? 56.094 57.968 -15.877 1.00 13.44 ? 441 MET A CE 1 ATOM 3504 N N . LEU A 1 442 ? 60.290 62.152 -13.928 1.00 12.64 ? 442 LEU A N 1 ATOM 3505 C CA . LEU A 1 442 ? 61.484 62.832 -14.456 1.00 12.66 ? 442 LEU A CA 1 ATOM 3506 C C . LEU A 1 442 ? 62.702 62.726 -13.555 1.00 13.80 ? 442 LEU A C 1 ATOM 3507 O O . LEU A 1 442 ? 63.803 62.480 -14.053 1.00 13.53 ? 442 LEU A O 1 ATOM 3508 C CB . LEU A 1 442 ? 61.238 64.316 -14.748 1.00 12.83 ? 442 LEU A CB 1 ATOM 3509 C CG . LEU A 1 442 ? 60.586 64.538 -16.118 1.00 11.57 ? 442 LEU A CG 1 ATOM 3510 C CD1 . LEU A 1 442 ? 59.997 65.911 -16.171 1.00 13.04 ? 442 LEU A CD1 1 ATOM 3511 C CD2 . LEU A 1 442 ? 61.669 64.385 -17.209 1.00 14.67 ? 442 LEU A CD2 1 ATOM 3512 N N . SER A 1 443 ? 62.493 62.822 -12.241 1.00 12.29 ? 443 SER A N 1 ATOM 3513 C CA . SER A 1 443 ? 63.603 62.740 -11.307 1.00 13.64 ? 443 SER A CA 1 ATOM 3514 C C . SER A 1 443 ? 63.974 61.322 -10.938 1.00 13.33 ? 443 SER A C 1 ATOM 3515 O O . SER A 1 443 ? 65.070 61.117 -10.417 1.00 15.71 ? 443 SER A O 1 ATOM 3516 C CB . SER A 1 443 ? 63.336 63.531 -10.045 1.00 12.49 ? 443 SER A CB 1 ATOM 3517 O OG . SER A 1 443 ? 62.232 62.990 -9.315 1.00 13.58 ? 443 SER A OG 1 ATOM 3518 N N . ALA A 1 444 ? 63.136 60.344 -11.275 1.00 11.39 ? 444 ALA A N 1 ATOM 3519 C CA . ALA A 1 444 ? 63.451 58.950 -10.948 1.00 12.51 ? 444 ALA A CA 1 ATOM 3520 C C . ALA A 1 444 ? 64.619 58.398 -11.743 1.00 13.27 ? 444 ALA A C 1 ATOM 3521 O O . ALA A 1 444 ? 65.229 57.422 -11.323 1.00 15.15 ? 444 ALA A O 1 ATOM 3522 C CB . ALA A 1 444 ? 62.224 58.030 -11.191 1.00 13.65 ? 444 ALA A CB 1 ATOM 3523 N N . TRP A 1 445 ? 64.892 58.966 -12.905 1.00 14.19 ? 445 TRP A N 1 ATOM 3524 C CA . TRP A 1 445 ? 65.943 58.410 -13.777 1.00 14.76 ? 445 TRP A CA 1 ATOM 3525 C C . TRP A 1 445 ? 67.320 58.474 -13.149 1.00 15.62 ? 445 TRP A C 1 ATOM 3526 O O . TRP A 1 445 ? 68.192 57.705 -13.547 1.00 17.40 ? 445 TRP A O 1 ATOM 3527 C CB . TRP A 1 445 ? 65.978 59.145 -15.118 1.00 14.01 ? 445 TRP A CB 1 ATOM 3528 C CG . TRP A 1 445 ? 64.690 58.966 -15.899 1.00 11.69 ? 445 TRP A CG 1 ATOM 3529 C CD1 . TRP A 1 445 ? 63.683 59.901 -16.047 1.00 13.07 ? 445 TRP A CD1 1 ATOM 3530 C CD2 . TRP A 1 445 ? 64.225 57.784 -16.570 1.00 13.04 ? 445 TRP A CD2 1 ATOM 3531 N NE1 . TRP A 1 445 ? 62.652 59.376 -16.752 1.00 12.70 ? 445 TRP A NE1 1 ATOM 3532 C CE2 . TRP A 1 445 ? 62.936 58.080 -17.083 1.00 12.50 ? 445 TRP A CE2 1 ATOM 3533 C CE3 . TRP A 1 445 ? 64.763 56.508 -16.781 1.00 13.18 ? 445 TRP A CE3 1 ATOM 3534 C CZ2 . TRP A 1 445 ? 62.179 57.150 -17.785 1.00 12.92 ? 445 TRP A CZ2 1 ATOM 3535 C CZ3 . TRP A 1 445 ? 64.011 55.576 -17.489 1.00 14.05 ? 445 TRP A CZ3 1 ATOM 3536 C CH2 . TRP A 1 445 ? 62.731 55.899 -17.983 1.00 15.07 ? 445 TRP A CH2 1 ATOM 3537 N N . HIS A 1 446 ? 67.512 59.410 -12.232 1.00 15.92 ? 446 HIS A N 1 ATOM 3538 C CA . HIS A 1 446 ? 68.796 59.546 -11.584 1.00 17.92 ? 446 HIS A CA 1 ATOM 3539 C C . HIS A 1 446 ? 68.686 59.485 -10.089 1.00 17.77 ? 446 HIS A C 1 ATOM 3540 O O . HIS A 1 446 ? 67.619 59.646 -9.503 1.00 17.28 ? 446 HIS A O 1 ATOM 3541 C CB . HIS A 1 446 ? 69.404 60.915 -11.835 1.00 19.61 ? 446 HIS A CB 1 ATOM 3542 C CG . HIS A 1 446 ? 69.869 61.137 -13.235 1.00 21.05 ? 446 HIS A CG 1 ATOM 3543 N ND1 . HIS A 1 446 ? 69.124 61.826 -14.166 1.00 22.50 ? 446 HIS A ND1 1 ATOM 3544 C CD2 . HIS A 1 446 ? 71.025 60.791 -13.856 1.00 25.35 ? 446 HIS A CD2 1 ATOM 3545 C CE1 . HIS A 1 446 ? 69.798 61.899 -15.301 1.00 25.20 ? 446 HIS A CE1 1 ATOM 3546 N NE2 . HIS A 1 446 ? 70.950 61.279 -15.140 1.00 26.11 ? 446 HIS A NE2 1 ATOM 3547 N N . SER A 1 447 ? 69.837 59.263 -9.464 1.00 17.83 ? 447 SER A N 1 ATOM 3548 C CA . SER A 1 447 ? 69.956 59.301 -8.024 1.00 16.33 ? 447 SER A CA 1 ATOM 3549 C C . SER A 1 447 ? 70.436 60.739 -7.808 1.00 17.75 ? 447 SER A C 1 ATOM 3550 O O . SER A 1 447 ? 71.242 61.256 -8.609 1.00 19.05 ? 447 SER A O 1 ATOM 3551 C CB . SER A 1 447 ? 71.004 58.301 -7.551 1.00 18.78 ? 447 SER A CB 1 ATOM 3552 O OG A SER A 1 447 ? 71.159 58.407 -6.154 0.50 18.40 ? 447 SER A OG 1 ATOM 3553 O OG B SER A 1 447 ? 70.654 57.584 -6.460 0.50 22.79 ? 447 SER A OG 1 ATOM 3554 N N . TRP A 1 448 ? 69.908 61.419 -6.796 1.00 15.83 ? 448 TRP A N 1 ATOM 3555 C CA . TRP A 1 448 ? 70.263 62.804 -6.532 1.00 16.65 ? 448 TRP A CA 1 ATOM 3556 C C . TRP A 1 448 ? 70.946 63.023 -5.211 1.00 18.55 ? 448 TRP A C 1 ATOM 3557 O O . TRP A 1 448 ? 70.619 62.394 -4.227 1.00 20.99 ? 448 TRP A O 1 ATOM 3558 C CB . TRP A 1 448 ? 69.023 63.728 -6.572 1.00 16.09 ? 448 TRP A CB 1 ATOM 3559 C CG . TRP A 1 448 ? 68.345 63.738 -7.934 1.00 16.29 ? 448 TRP A CG 1 ATOM 3560 C CD1 . TRP A 1 448 ? 67.510 62.794 -8.446 1.00 15.80 ? 448 TRP A CD1 1 ATOM 3561 C CD2 . TRP A 1 448 ? 68.494 64.742 -8.935 1.00 15.63 ? 448 TRP A CD2 1 ATOM 3562 N NE1 . TRP A 1 448 ? 67.120 63.147 -9.734 1.00 14.86 ? 448 TRP A NE1 1 ATOM 3563 C CE2 . TRP A 1 448 ? 67.710 64.344 -10.041 1.00 14.28 ? 448 TRP A CE2 1 ATOM 3564 C CE3 . TRP A 1 448 ? 69.217 65.949 -9.003 1.00 17.17 ? 448 TRP A CE3 1 ATOM 3565 C CZ2 . TRP A 1 448 ? 67.624 65.098 -11.192 1.00 16.60 ? 448 TRP A CZ2 1 ATOM 3566 C CZ3 . TRP A 1 448 ? 69.126 66.716 -10.184 1.00 15.28 ? 448 TRP A CZ3 1 ATOM 3567 C CH2 . TRP A 1 448 ? 68.328 66.264 -11.258 1.00 16.32 ? 448 TRP A CH2 1 ATOM 3568 N N . ASP A 1 449 ? 71.890 63.949 -5.211 1.00 21.65 ? 449 ASP A N 1 ATOM 3569 C CA . ASP A 1 449 ? 72.582 64.320 -3.993 1.00 23.82 ? 449 ASP A CA 1 ATOM 3570 C C . ASP A 1 449 ? 71.559 64.946 -3.042 1.00 24.51 ? 449 ASP A C 1 ATOM 3571 O O . ASP A 1 449 ? 70.646 65.645 -3.470 1.00 20.97 ? 449 ASP A O 1 ATOM 3572 C CB . ASP A 1 449 ? 73.634 65.358 -4.336 1.00 28.31 ? 449 ASP A CB 1 ATOM 3573 C CG . ASP A 1 449 ? 74.557 65.637 -3.192 1.00 31.18 ? 449 ASP A CG 1 ATOM 3574 O OD1 . ASP A 1 449 ? 74.217 66.450 -2.312 1.00 33.37 ? 449 ASP A OD1 1 ATOM 3575 O OD2 . ASP A 1 449 ? 75.633 65.004 -3.183 1.00 38.77 ? 449 ASP A OD2 1 ATOM 3576 N N . GLY A 1 450 ? 71.738 64.724 -1.748 1.00 22.27 ? 450 GLY A N 1 ATOM 3577 C CA . GLY A 1 450 ? 70.828 65.307 -0.771 1.00 22.95 ? 450 GLY A CA 1 ATOM 3578 C C . GLY A 1 450 ? 70.701 66.805 -0.899 1.00 23.91 ? 450 GLY A C 1 ATOM 3579 O O . GLY A 1 450 ? 69.644 67.378 -0.585 1.00 24.59 ? 450 GLY A O 1 ATOM 3580 N N . MET A 1 451 ? 71.774 67.462 -1.357 1.00 21.70 ? 451 MET A N 1 ATOM 3581 C CA . MET A 1 451 ? 71.751 68.910 -1.507 1.00 23.76 ? 451 MET A CA 1 ATOM 3582 C C . MET A 1 451 ? 70.772 69.404 -2.560 1.00 20.55 ? 451 MET A C 1 ATOM 3583 O O . MET A 1 451 ? 70.391 70.576 -2.550 1.00 23.66 ? 451 MET A O 1 ATOM 3584 C CB . MET A 1 451 ? 73.145 69.436 -1.869 1.00 28.61 ? 451 MET A CB 1 ATOM 3585 C CG . MET A 1 451 ? 74.161 69.334 -0.764 1.00 37.57 ? 451 MET A CG 1 ATOM 3586 S SD . MET A 1 451 ? 73.666 70.249 0.745 1.00 49.88 ? 451 MET A SD 1 ATOM 3587 C CE . MET A 1 451 ? 73.044 68.847 1.816 1.00 46.21 ? 451 MET A CE 1 ATOM 3588 N N . ALA A 1 452 ? 70.373 68.517 -3.476 1.00 18.55 ? 452 ALA A N 1 ATOM 3589 C CA . ALA A 1 452 ? 69.425 68.918 -4.517 1.00 18.05 ? 452 ALA A CA 1 ATOM 3590 C C . ALA A 1 452 ? 68.003 69.054 -3.985 1.00 19.23 ? 452 ALA A C 1 ATOM 3591 O O . ALA A 1 452 ? 67.137 69.582 -4.684 1.00 20.21 ? 452 ALA A O 1 ATOM 3592 C CB . ALA A 1 452 ? 69.435 67.917 -5.657 1.00 17.13 ? 452 ALA A CB 1 ATOM 3593 N N . ARG A 1 453 ? 67.762 68.542 -2.776 1.00 17.99 ? 453 ARG A N 1 ATOM 3594 C CA . ARG A 1 453 ? 66.439 68.632 -2.142 1.00 20.41 ? 453 ARG A CA 1 ATOM 3595 C C . ARG A 1 453 ? 65.309 68.049 -3.001 1.00 18.88 ? 453 ARG A C 1 ATOM 3596 O O . ARG A 1 453 ? 64.181 68.520 -2.922 1.00 19.33 ? 453 ARG A O 1 ATOM 3597 C CB . ARG A 1 453 ? 66.131 70.087 -1.810 1.00 20.93 ? 453 ARG A CB 1 ATOM 3598 C CG . ARG A 1 453 ? 67.207 70.699 -0.901 1.00 22.48 ? 453 ARG A CG 1 ATOM 3599 C CD . ARG A 1 453 ? 66.969 72.196 -0.681 1.00 25.72 ? 453 ARG A CD 1 ATOM 3600 N NE . ARG A 1 453 ? 65.803 72.466 0.157 1.00 26.68 ? 453 ARG A NE 1 ATOM 3601 C CZ . ARG A 1 453 ? 65.342 73.697 0.377 1.00 30.15 ? 453 ARG A CZ 1 ATOM 3602 N NH1 . ARG A 1 453 ? 65.961 74.752 -0.188 1.00 29.45 ? 453 ARG A NH1 1 ATOM 3603 N NH2 . ARG A 1 453 ? 64.274 73.874 1.150 1.00 32.23 ? 453 ARG A NH2 1 ATOM 3604 N N . ILE A 1 454 ? 65.620 67.034 -3.794 1.00 15.82 ? 454 ILE A N 1 ATOM 3605 C CA . ILE A 1 454 ? 64.613 66.413 -4.639 1.00 14.63 ? 454 ILE A CA 1 ATOM 3606 C C . ILE A 1 454 ? 63.591 65.643 -3.781 1.00 16.97 ? 454 ILE A C 1 ATOM 3607 O O . ILE A 1 454 ? 62.393 65.876 -3.911 1.00 15.40 ? 454 ILE A O 1 ATOM 3608 C CB . ILE A 1 454 ? 65.272 65.468 -5.675 1.00 14.84 ? 454 ILE A CB 1 ATOM 3609 C CG1 . ILE A 1 454 ? 66.221 66.274 -6.587 1.00 16.60 ? 454 ILE A CG1 1 ATOM 3610 C CG2 . ILE A 1 454 ? 64.202 64.629 -6.395 1.00 15.60 ? 454 ILE A CG2 1 ATOM 3611 C CD1 . ILE A 1 454 ? 65.556 67.384 -7.400 1.00 17.98 ? 454 ILE A CD1 1 ATOM 3612 N N . GLU A 1 455 ? 64.063 64.775 -2.887 1.00 15.41 ? 455 GLU A N 1 ATOM 3613 C CA . GLU A 1 455 ? 63.140 64.002 -2.044 1.00 16.21 ? 455 GLU A CA 1 ATOM 3614 C C . GLU A 1 455 ? 62.278 64.927 -1.210 1.00 16.18 ? 455 GLU A C 1 ATOM 3615 O O . GLU A 1 455 ? 61.080 64.676 -1.027 1.00 15.99 ? 455 GLU A O 1 ATOM 3616 C CB . GLU A 1 455 ? 63.913 63.042 -1.125 1.00 15.88 ? 455 GLU A CB 1 ATOM 3617 C CG . GLU A 1 455 ? 64.514 61.829 -1.838 1.00 18.34 ? 455 GLU A CG 1 ATOM 3618 C CD . GLU A 1 455 ? 65.887 62.124 -2.481 1.00 18.18 ? 455 GLU A CD 1 ATOM 3619 O OE1 . GLU A 1 455 ? 66.334 63.291 -2.400 1.00 19.51 ? 455 GLU A OE1 1 ATOM 3620 O OE2 . GLU A 1 455 ? 66.461 61.175 -3.038 1.00 18.56 ? 455 GLU A OE2 1 ATOM 3621 N N . GLU A 1 456 ? 62.884 65.979 -0.681 1.00 16.30 ? 456 GLU A N 1 ATOM 3622 C CA . GLU A 1 456 ? 62.179 66.933 0.143 1.00 15.01 ? 456 GLU A CA 1 ATOM 3623 C C . GLU A 1 456 ? 61.011 67.575 -0.619 1.00 15.80 ? 456 GLU A C 1 ATOM 3624 O O . GLU A 1 456 ? 59.887 67.629 -0.132 1.00 15.23 ? 456 GLU A O 1 ATOM 3625 C CB . GLU A 1 456 ? 63.177 68.017 0.623 1.00 19.04 ? 456 GLU A CB 1 ATOM 3626 C CG . GLU A 1 456 ? 62.546 69.149 1.392 1.00 21.07 ? 456 GLU A CG 1 ATOM 3627 C CD . GLU A 1 456 ? 63.477 70.342 1.629 1.00 29.12 ? 456 GLU A CD 1 ATOM 3628 O OE1 . GLU A 1 456 ? 64.712 70.208 1.444 1.00 29.87 ? 456 GLU A OE1 1 ATOM 3629 O OE2 . GLU A 1 456 ? 62.962 71.420 2.020 1.00 28.97 ? 456 GLU A OE2 1 ATOM 3630 N N . ARG A 1 457 ? 61.281 68.071 -1.828 1.00 14.86 ? 457 ARG A N 1 ATOM 3631 C CA . ARG A 1 457 ? 60.214 68.742 -2.602 1.00 12.93 ? 457 ARG A CA 1 ATOM 3632 C C . ARG A 1 457 ? 59.149 67.745 -3.051 1.00 14.15 ? 457 ARG A C 1 ATOM 3633 O O . ARG A 1 457 ? 57.969 68.092 -3.037 1.00 14.36 ? 457 ARG A O 1 ATOM 3634 C CB . ARG A 1 457 ? 60.843 69.483 -3.811 1.00 13.93 ? 457 ARG A CB 1 ATOM 3635 C CG . ARG A 1 457 ? 61.165 70.952 -3.568 1.00 17.45 ? 457 ARG A CG 1 ATOM 3636 C CD . ARG A 1 457 ? 62.154 71.166 -2.468 1.00 19.10 ? 457 ARG A CD 1 ATOM 3637 N NE . ARG A 1 457 ? 62.384 72.598 -2.179 1.00 20.66 ? 457 ARG A NE 1 ATOM 3638 C CZ . ARG A 1 457 ? 63.305 73.346 -2.792 1.00 23.45 ? 457 ARG A CZ 1 ATOM 3639 N NH1 . ARG A 1 457 ? 64.093 72.823 -3.735 1.00 21.00 ? 457 ARG A NH1 1 ATOM 3640 N NH2 . ARG A 1 457 ? 63.463 74.623 -2.445 1.00 26.40 ? 457 ARG A NH2 1 ATOM 3641 N N . LEU A 1 458 ? 59.557 66.532 -3.407 1.00 12.84 ? 458 LEU A N 1 ATOM 3642 C CA . LEU A 1 458 ? 58.564 65.531 -3.818 1.00 13.12 ? 458 LEU A CA 1 ATOM 3643 C C . LEU A 1 458 ? 57.690 65.117 -2.651 1.00 14.27 ? 458 LEU A C 1 ATOM 3644 O O . LEU A 1 458 ? 56.480 64.928 -2.841 1.00 13.82 ? 458 LEU A O 1 ATOM 3645 C CB . LEU A 1 458 ? 59.244 64.317 -4.425 1.00 12.53 ? 458 LEU A CB 1 ATOM 3646 C CG . LEU A 1 458 ? 59.935 64.625 -5.795 1.00 12.66 ? 458 LEU A CG 1 ATOM 3647 C CD1 . LEU A 1 458 ? 60.661 63.392 -6.224 1.00 16.02 ? 458 LEU A CD1 1 ATOM 3648 C CD2 . LEU A 1 458 ? 58.874 65.061 -6.910 1.00 14.77 ? 458 LEU A CD2 1 ATOM 3649 N N . GLU A 1 459 ? 58.267 64.981 -1.442 1.00 12.57 ? 459 GLU A N 1 ATOM 3650 C CA . GLU A 1 459 ? 57.431 64.592 -0.293 1.00 13.06 ? 459 GLU A CA 1 ATOM 3651 C C . GLU A 1 459 ? 56.406 65.716 -0.011 1.00 13.88 ? 459 GLU A C 1 ATOM 3652 O O . GLU A 1 459 ? 55.226 65.454 0.271 1.00 13.15 ? 459 GLU A O 1 ATOM 3653 C CB . GLU A 1 459 ? 58.334 64.408 0.927 1.00 15.38 ? 459 GLU A CB 1 ATOM 3654 C CG . GLU A 1 459 ? 57.551 64.026 2.196 1.00 18.17 ? 459 GLU A CG 1 ATOM 3655 C CD . GLU A 1 459 ? 58.443 63.358 3.231 1.00 20.94 ? 459 GLU A CD 1 ATOM 3656 O OE1 . GLU A 1 459 ? 59.073 64.107 3.966 1.00 24.19 ? 459 GLU A OE1 1 ATOM 3657 O OE2 . GLU A 1 459 ? 58.531 62.110 3.290 1.00 25.55 ? 459 GLU A OE2 1 ATOM 3658 N N . GLN A 1 460 ? 56.842 66.972 -0.098 1.00 12.27 ? 460 GLN A N 1 ATOM 3659 C CA . GLN A 1 460 ? 55.926 68.071 0.128 1.00 12.90 ? 460 GLN A CA 1 ATOM 3660 C C . GLN A 1 460 ? 54.776 68.003 -0.898 1.00 13.40 ? 460 GLN A C 1 ATOM 3661 O O . GLN A 1 460 ? 53.601 68.091 -0.570 1.00 14.94 ? 460 GLN A O 1 ATOM 3662 C CB . GLN A 1 460 ? 56.670 69.374 -0.052 1.00 15.95 ? 460 GLN A CB 1 ATOM 3663 C CG . GLN A 1 460 ? 55.784 70.591 0.072 1.00 20.14 ? 460 GLN A CG 1 ATOM 3664 C CD . GLN A 1 460 ? 56.566 71.885 -0.159 1.00 25.07 ? 460 GLN A CD 1 ATOM 3665 O OE1 . GLN A 1 460 ? 56.113 72.938 0.226 1.00 33.40 ? 460 GLN A OE1 1 ATOM 3666 N NE2 . GLN A 1 460 ? 57.708 71.796 -0.836 1.00 27.11 ? 460 GLN A NE2 1 ATOM 3667 N N . ALA A 1 461 ? 55.149 67.819 -2.154 1.00 12.67 ? 461 ALA A N 1 ATOM 3668 C CA . ALA A 1 461 ? 54.104 67.766 -3.173 1.00 12.82 ? 461 ALA A CA 1 ATOM 3669 C C . ALA A 1 461 ? 53.124 66.614 -3.000 1.00 14.18 ? 461 ALA A C 1 ATOM 3670 O O . ALA A 1 461 ? 51.915 66.819 -3.108 1.00 13.20 ? 461 ALA A O 1 ATOM 3671 C CB . ALA A 1 461 ? 54.753 67.730 -4.573 1.00 13.94 ? 461 ALA A CB 1 ATOM 3672 N N . ARG A 1 462 ? 53.641 65.419 -2.705 1.00 12.39 ? 462 ARG A N 1 ATOM 3673 C CA . ARG A 1 462 ? 52.771 64.271 -2.518 1.00 11.67 ? 462 ARG A CA 1 ATOM 3674 C C . ARG A 1 462 ? 51.852 64.517 -1.316 1.00 12.46 ? 462 ARG A C 1 ATOM 3675 O O . ARG A 1 462 ? 50.674 64.157 -1.351 1.00 12.13 ? 462 ARG A O 1 ATOM 3676 C CB . ARG A 1 462 ? 53.551 62.991 -2.228 1.00 11.92 ? 462 ARG A CB 1 ATOM 3677 C CG . ARG A 1 462 ? 54.301 62.430 -3.461 1.00 11.82 ? 462 ARG A CG 1 ATOM 3678 C CD . ARG A 1 462 ? 54.767 61.009 -3.219 1.00 11.90 ? 462 ARG A CD 1 ATOM 3679 N NE . ARG A 1 462 ? 55.694 60.964 -2.057 1.00 11.69 ? 462 ARG A NE 1 ATOM 3680 C CZ . ARG A 1 462 ? 57.017 61.103 -2.146 1.00 14.70 ? 462 ARG A CZ 1 ATOM 3681 N NH1 . ARG A 1 462 ? 57.635 61.269 -3.316 1.00 14.07 ? 462 ARG A NH1 1 ATOM 3682 N NH2 . ARG A 1 462 ? 57.761 61.119 -1.050 1.00 17.55 ? 462 ARG A NH2 1 ATOM 3683 N N . ARG A 1 463 ? 52.380 65.145 -0.262 1.00 12.31 ? 463 ARG A N 1 ATOM 3684 C CA . ARG A 1 463 ? 51.555 65.317 0.928 1.00 12.24 ? 463 ARG A CA 1 ATOM 3685 C C . ARG A 1 463 ? 50.495 66.369 0.749 1.00 12.02 ? 463 ARG A C 1 ATOM 3686 O O . ARG A 1 463 ? 49.379 66.182 1.269 1.00 13.13 ? 463 ARG A O 1 ATOM 3687 C CB . ARG A 1 463 ? 52.441 65.607 2.156 1.00 12.42 ? 463 ARG A CB 1 ATOM 3688 C CG . ARG A 1 463 ? 53.165 64.351 2.557 1.00 12.91 ? 463 ARG A CG 1 ATOM 3689 C CD . ARG A 1 463 ? 54.184 64.574 3.652 1.00 15.21 ? 463 ARG A CD 1 ATOM 3690 N NE . ARG A 1 463 ? 54.672 63.246 4.009 1.00 15.76 ? 463 ARG A NE 1 ATOM 3691 C CZ . ARG A 1 463 ? 55.432 62.984 5.071 1.00 19.16 ? 463 ARG A CZ 1 ATOM 3692 N NH1 . ARG A 1 463 ? 55.798 63.975 5.848 1.00 19.72 ? 463 ARG A NH1 1 ATOM 3693 N NH2 . ARG A 1 463 ? 55.758 61.724 5.358 1.00 20.25 ? 463 ARG A NH2 1 ATOM 3694 N N . GLU A 1 464 ? 50.762 67.450 0.010 1.00 12.12 ? 464 GLU A N 1 ATOM 3695 C CA . GLU A 1 464 ? 49.716 68.455 -0.126 1.00 13.09 ? 464 GLU A CA 1 ATOM 3696 C C . GLU A 1 464 ? 48.623 67.933 -1.053 1.00 12.85 ? 464 GLU A C 1 ATOM 3697 O O . GLU A 1 464 ? 47.435 68.170 -0.801 1.00 13.67 ? 464 GLU A O 1 ATOM 3698 C CB . GLU A 1 464 ? 50.251 69.803 -0.680 1.00 14.85 ? 464 GLU A CB 1 ATOM 3699 C CG . GLU A 1 464 ? 51.462 70.390 0.115 1.00 18.04 ? 464 GLU A CG 1 ATOM 3700 C CD . GLU A 1 464 ? 51.156 70.849 1.529 1.00 23.10 ? 464 GLU A CD 1 ATOM 3701 O OE1 . GLU A 1 464 ? 50.166 70.417 2.114 1.00 20.71 ? 464 GLU A OE1 1 ATOM 3702 O OE2 . GLU A 1 464 ? 51.963 71.648 2.067 1.00 25.93 ? 464 GLU A OE2 1 ATOM 3703 N N . LEU A 1 465 ? 49.009 67.223 -2.115 1.00 12.63 ? 465 LEU A N 1 ATOM 3704 C CA . LEU A 1 465 ? 47.965 66.665 -2.995 1.00 11.88 ? 465 LEU A CA 1 ATOM 3705 C C . LEU A 1 465 ? 47.177 65.591 -2.206 1.00 12.04 ? 465 LEU A C 1 ATOM 3706 O O . LEU A 1 465 ? 45.958 65.477 -2.331 1.00 12.11 ? 465 LEU A O 1 ATOM 3707 C CB . LEU A 1 465 ? 48.612 66.013 -4.223 1.00 11.85 ? 465 LEU A CB 1 ATOM 3708 C CG . LEU A 1 465 ? 47.634 65.377 -5.230 1.00 11.10 ? 465 LEU A CG 1 ATOM 3709 C CD1 . LEU A 1 465 ? 46.557 66.391 -5.710 1.00 11.80 ? 465 LEU A CD1 1 ATOM 3710 C CD2 . LEU A 1 465 ? 48.429 64.843 -6.437 1.00 13.23 ? 465 LEU A CD2 1 ATOM 3711 N N . SER A 1 466 ? 47.889 64.777 -1.399 1.00 10.66 ? 466 SER A N 1 ATOM 3712 C CA . SER A 1 466 ? 47.216 63.721 -0.643 1.00 10.06 ? 466 SER A CA 1 ATOM 3713 C C . SER A 1 466 ? 46.212 64.321 0.361 1.00 10.46 ? 466 SER A C 1 ATOM 3714 O O . SER A 1 466 ? 45.090 63.801 0.519 1.00 11.03 ? 466 SER A O 1 ATOM 3715 C CB . SER A 1 466 ? 48.232 62.894 0.130 1.00 10.21 ? 466 SER A CB 1 ATOM 3716 O OG . SER A 1 466 ? 48.990 62.081 -0.761 1.00 12.21 ? 466 SER A OG 1 ATOM 3717 N N . LEU A 1 467 ? 46.617 65.411 1.021 1.00 10.38 ? 467 LEU A N 1 ATOM 3718 C CA . LEU A 1 467 ? 45.755 66.079 1.983 1.00 11.72 ? 467 LEU A CA 1 ATOM 3719 C C . LEU A 1 467 ? 44.453 66.526 1.288 1.00 10.54 ? 467 LEU A C 1 ATOM 3720 O O . LEU A 1 467 ? 43.356 66.376 1.831 1.00 10.52 ? 467 LEU A O 1 ATOM 3721 C CB . LEU A 1 467 ? 46.499 67.285 2.566 1.00 11.72 ? 467 LEU A CB 1 ATOM 3722 C CG . LEU A 1 467 ? 45.629 68.064 3.570 1.00 15.86 ? 467 LEU A CG 1 ATOM 3723 C CD1 . LEU A 1 467 ? 45.407 67.269 4.822 1.00 22.27 ? 467 LEU A CD1 1 ATOM 3724 C CD2 . LEU A 1 467 ? 46.298 69.405 3.894 1.00 17.15 ? 467 LEU A CD2 1 ATOM 3725 N N . PHE A 1 468 ? 44.578 67.003 0.051 1.00 10.82 ? 468 PHE A N 1 ATOM 3726 C CA . PHE A 1 468 ? 43.400 67.536 -0.657 1.00 10.77 ? 468 PHE A CA 1 ATOM 3727 C C . PHE A 1 468 ? 42.416 66.441 -1.036 1.00 10.14 ? 468 PHE A C 1 ATOM 3728 O O . PHE A 1 468 ? 41.281 66.725 -1.363 1.00 12.09 ? 468 PHE A O 1 ATOM 3729 C CB . PHE A 1 468 ? 43.821 68.329 -1.910 1.00 10.53 ? 468 PHE A CB 1 ATOM 3730 C CG . PHE A 1 468 ? 42.697 69.176 -2.462 1.00 9.66 ? 468 PHE A CG 1 ATOM 3731 C CD1 . PHE A 1 468 ? 42.035 70.110 -1.680 1.00 11.69 ? 468 PHE A CD1 1 ATOM 3732 C CD2 . PHE A 1 468 ? 42.261 68.985 -3.779 1.00 10.00 ? 468 PHE A CD2 1 ATOM 3733 C CE1 . PHE A 1 468 ? 40.941 70.859 -2.173 1.00 11.53 ? 468 PHE A CE1 1 ATOM 3734 C CE2 . PHE A 1 468 ? 41.172 69.720 -4.293 1.00 10.30 ? 468 PHE A CE2 1 ATOM 3735 C CZ . PHE A 1 468 ? 40.501 70.658 -3.497 1.00 11.69 ? 468 PHE A CZ 1 ATOM 3736 N N . GLN A 1 469 ? 42.865 65.189 -1.028 1.00 9.16 ? 469 GLN A N 1 ATOM 3737 C CA . GLN A 1 469 ? 41.906 64.121 -1.264 1.00 9.43 ? 469 GLN A CA 1 ATOM 3738 C C . GLN A 1 469 ? 40.871 63.926 -0.170 1.00 10.47 ? 469 GLN A C 1 ATOM 3739 O O . GLN A 1 469 ? 39.909 63.155 -0.329 1.00 11.21 ? 469 GLN A O 1 ATOM 3740 C CB . GLN A 1 469 ? 42.640 62.793 -1.436 1.00 10.99 ? 469 GLN A CB 1 ATOM 3741 C CG . GLN A 1 469 ? 43.725 62.849 -2.584 1.00 9.58 ? 469 GLN A CG 1 ATOM 3742 C CD . GLN A 1 469 ? 43.252 63.532 -3.846 1.00 11.34 ? 469 GLN A CD 1 ATOM 3743 O OE1 . GLN A 1 469 ? 43.814 64.571 -4.315 1.00 13.77 ? 469 GLN A OE1 1 ATOM 3744 N NE2 . GLN A 1 469 ? 42.212 63.004 -4.388 1.00 8.90 ? 469 GLN A NE2 1 ATOM 3745 N N . HIS A 1 470 ? 41.110 64.573 0.960 1.00 9.75 ? 470 HIS A N 1 ATOM 3746 C CA . HIS A 1 470 ? 40.157 64.534 2.080 1.00 11.34 ? 470 HIS A CA 1 ATOM 3747 C C . HIS A 1 470 ? 38.734 64.781 1.578 1.00 11.33 ? 470 HIS A C 1 ATOM 3748 O O . HIS A 1 470 ? 38.512 65.562 0.632 1.00 11.00 ? 470 HIS A O 1 ATOM 3749 C CB . HIS A 1 470 ? 40.529 65.622 3.096 1.00 10.21 ? 470 HIS A CB 1 ATOM 3750 C CG . HIS A 1 470 ? 39.538 65.751 4.200 1.00 11.44 ? 470 HIS A CG 1 ATOM 3751 N ND1 . HIS A 1 470 ? 39.046 66.942 4.667 1.00 14.61 ? 470 HIS A ND1 1 ATOM 3752 C CD2 . HIS A 1 470 ? 38.908 64.779 4.903 1.00 9.59 ? 470 HIS A CD2 1 ATOM 3753 C CE1 . HIS A 1 470 ? 38.146 66.701 5.617 1.00 10.06 ? 470 HIS A CE1 1 ATOM 3754 N NE2 . HIS A 1 470 ? 38.054 65.394 5.775 1.00 15.72 ? 470 HIS A NE2 1 ATOM 3755 N N . HIS A 1 471 ? 37.762 64.155 2.252 1.00 10.88 ? 471 HIS A N 1 ATOM 3756 C CA . HIS A 1 471 ? 36.360 64.302 1.892 1.00 11.61 ? 471 HIS A CA 1 ATOM 3757 C C . HIS A 1 471 ? 35.715 65.676 2.162 1.00 11.09 ? 471 HIS A C 1 ATOM 3758 O O . HIS A 1 471 ? 34.523 65.785 1.959 1.00 12.94 ? 471 HIS A O 1 ATOM 3759 C CB . HIS A 1 471 ? 35.514 63.152 2.505 1.00 11.77 ? 471 HIS A CB 1 ATOM 3760 C CG . HIS A 1 471 ? 35.585 63.056 3.994 1.00 10.59 ? 471 HIS A CG 1 ATOM 3761 N ND1 . HIS A 1 471 ? 36.566 62.336 4.646 1.00 10.45 ? 471 HIS A ND1 1 ATOM 3762 C CD2 . HIS A 1 471 ? 34.837 63.655 4.957 1.00 12.23 ? 471 HIS A CD2 1 ATOM 3763 C CE1 . HIS A 1 471 ? 36.422 62.503 5.953 1.00 10.72 ? 471 HIS A CE1 1 ATOM 3764 N NE2 . HIS A 1 471 ? 35.387 63.294 6.171 1.00 9.32 ? 471 HIS A NE2 1 ATOM 3765 N N . ASP A 1 472 ? 36.508 66.678 2.624 1.00 12.14 ? 472 ASP A N 1 ATOM 3766 C CA . ASP A 1 472 ? 36.041 68.068 2.621 1.00 13.25 ? 472 ASP A CA 1 ATOM 3767 C C . ASP A 1 472 ? 37.044 68.904 1.827 1.00 13.58 ? 472 ASP A C 1 ATOM 3768 O O . ASP A 1 472 ? 36.922 70.129 1.840 1.00 14.39 ? 472 ASP A O 1 ATOM 3769 C CB . ASP A 1 472 ? 35.880 68.673 4.012 1.00 13.48 ? 472 ASP A CB 1 ATOM 3770 C CG . ASP A 1 472 ? 34.783 67.968 4.824 1.00 12.84 ? 472 ASP A CG 1 ATOM 3771 O OD1 . ASP A 1 472 ? 33.589 68.046 4.428 1.00 13.34 ? 472 ASP A OD1 1 ATOM 3772 O OD2 . ASP A 1 472 ? 35.196 67.317 5.800 1.00 13.13 ? 472 ASP A OD2 1 ATOM 3773 N N . GLY A 1 473 ? 37.973 68.270 1.110 1.00 10.52 ? 473 GLY A N 1 ATOM 3774 C CA . GLY A 1 473 ? 38.940 69.027 0.311 1.00 12.70 ? 473 GLY A CA 1 ATOM 3775 C C . GLY A 1 473 ? 38.437 69.101 -1.122 1.00 11.69 ? 473 GLY A C 1 ATOM 3776 O O . GLY A 1 473 ? 37.718 70.034 -1.511 1.00 11.74 ? 473 GLY A O 1 ATOM 3777 N N . ILE A 1 474 ? 38.757 68.061 -1.894 1.00 10.89 ? 474 ILE A N 1 ATOM 3778 C CA . ILE A 1 474 ? 38.343 68.050 -3.286 1.00 12.48 ? 474 ILE A CA 1 ATOM 3779 C C . ILE A 1 474 ? 36.841 68.173 -3.467 1.00 11.99 ? 474 ILE A C 1 ATOM 3780 O O . ILE A 1 474 ? 36.376 68.662 -4.520 1.00 11.95 ? 474 ILE A O 1 ATOM 3781 C CB . ILE A 1 474 ? 38.934 66.793 -3.990 1.00 11.16 ? 474 ILE A CB 1 ATOM 3782 C CG1 . ILE A 1 474 ? 38.677 66.875 -5.474 1.00 12.23 ? 474 ILE A CG1 1 ATOM 3783 C CG2 . ILE A 1 474 ? 38.356 65.481 -3.370 1.00 11.98 ? 474 ILE A CG2 1 ATOM 3784 C CD1 . ILE A 1 474 ? 39.428 65.726 -6.252 1.00 13.22 ? 474 ILE A CD1 1 ATOM 3785 N N . THR A 1 475 ? 36.069 67.748 -2.462 1.00 10.99 ? 475 THR A N 1 ATOM 3786 C CA . THR A 1 475 ? 34.616 67.832 -2.495 1.00 11.81 ? 475 THR A CA 1 ATOM 3787 C C . THR A 1 475 ? 34.060 69.273 -2.512 1.00 11.05 ? 475 THR A C 1 ATOM 3788 O O . THR A 1 475 ? 32.899 69.493 -2.850 1.00 11.97 ? 475 THR A O 1 ATOM 3789 C CB . THR A 1 475 ? 34.039 67.176 -1.227 1.00 12.99 ? 475 THR A CB 1 ATOM 3790 O OG1 . THR A 1 475 ? 34.579 67.895 -0.103 1.00 13.09 ? 475 THR A OG1 1 ATOM 3791 C CG2 . THR A 1 475 ? 34.411 65.692 -1.143 1.00 12.90 ? 475 THR A CG2 1 ATOM 3792 N N . GLY A 1 476 ? 34.885 70.245 -2.133 1.00 10.65 ? 476 GLY A N 1 ATOM 3793 C CA . GLY A 1 476 ? 34.414 71.618 -2.117 1.00 11.26 ? 476 GLY A CA 1 ATOM 3794 C C . GLY A 1 476 ? 33.444 71.882 -0.965 1.00 11.51 ? 476 GLY A C 1 ATOM 3795 O O . GLY A 1 476 ? 32.560 72.734 -1.116 1.00 13.08 ? 476 GLY A O 1 ATOM 3796 N N . THR A 1 477 ? 33.606 71.173 0.156 1.00 11.85 ? 477 THR A N 1 ATOM 3797 C CA . THR A 1 477 ? 32.713 71.322 1.282 1.00 11.78 ? 477 THR A CA 1 ATOM 3798 C C . THR A 1 477 ? 33.344 71.906 2.525 1.00 13.00 ? 477 THR A C 1 ATOM 3799 O O . THR A 1 477 ? 32.807 71.741 3.616 1.00 15.27 ? 477 THR A O 1 ATOM 3800 C CB . THR A 1 477 ? 32.037 69.977 1.608 1.00 12.13 ? 477 THR A CB 1 ATOM 3801 O OG1 . THR A 1 477 ? 33.030 68.961 1.846 1.00 13.70 ? 477 THR A OG1 1 ATOM 3802 C CG2 . THR A 1 477 ? 31.187 69.534 0.386 1.00 12.67 ? 477 THR A CG2 1 ATOM 3803 N N . ALA A 1 478 ? 34.430 72.660 2.380 1.00 12.70 ? 478 ALA A N 1 ATOM 3804 C CA . ALA A 1 478 ? 35.089 73.267 3.552 1.00 12.79 ? 478 ALA A CA 1 ATOM 3805 C C . ALA A 1 478 ? 34.791 74.762 3.624 1.00 13.45 ? 478 ALA A C 1 ATOM 3806 O O . ALA A 1 478 ? 34.287 75.379 2.690 1.00 13.87 ? 478 ALA A O 1 ATOM 3807 C CB . ALA A 1 478 ? 36.627 73.020 3.488 1.00 14.82 ? 478 ALA A CB 1 ATOM 3808 N N . LYS A 1 479 ? 35.092 75.356 4.769 1.00 14.43 ? 479 LYS A N 1 ATOM 3809 C CA . LYS A 1 479 ? 34.848 76.800 4.878 1.00 13.81 ? 479 LYS A CA 1 ATOM 3810 C C . LYS A 1 479 ? 35.811 77.551 3.945 1.00 13.63 ? 479 LYS A C 1 ATOM 3811 O O . LYS A 1 479 ? 36.882 77.052 3.566 1.00 13.29 ? 479 LYS A O 1 ATOM 3812 C CB . LYS A 1 479 ? 35.048 77.249 6.326 1.00 14.75 ? 479 LYS A CB 1 ATOM 3813 C CG . LYS A 1 479 ? 33.793 76.947 7.213 1.00 20.02 ? 479 LYS A CG 1 ATOM 3814 C CD . LYS A 1 479 ? 33.890 77.648 8.557 1.00 23.49 ? 479 LYS A CD 1 ATOM 3815 C CE . LYS A 1 479 ? 32.567 77.551 9.351 1.00 23.64 ? 479 LYS A CE 1 ATOM 3816 N NZ . LYS A 1 479 ? 31.393 78.273 8.731 1.00 23.96 ? 479 LYS A NZ 1 ATOM 3817 N N . THR A 1 480 ? 35.424 78.769 3.596 1.00 14.20 ? 480 THR A N 1 ATOM 3818 C CA . THR A 1 480 ? 36.224 79.582 2.709 1.00 13.82 ? 480 THR A CA 1 ATOM 3819 C C . THR A 1 480 ? 37.706 79.672 3.066 1.00 14.55 ? 480 THR A C 1 ATOM 3820 O O . THR A 1 480 ? 38.572 79.451 2.194 1.00 15.14 ? 480 THR A O 1 ATOM 3821 C CB . THR A 1 480 ? 35.632 80.992 2.660 1.00 17.90 ? 480 THR A CB 1 ATOM 3822 O OG1 . THR A 1 480 ? 34.292 80.889 2.196 1.00 21.06 ? 480 THR A OG1 1 ATOM 3823 C CG2 . THR A 1 480 ? 36.413 81.890 1.673 1.00 18.86 ? 480 THR A CG2 1 ATOM 3824 N N . HIS A 1 481 ? 38.040 79.967 4.323 1.00 14.37 ? 481 HIS A N 1 ATOM 3825 C CA . HIS A 1 481 ? 39.454 80.067 4.648 1.00 13.99 ? 481 HIS A CA 1 ATOM 3826 C C . HIS A 1 481 ? 40.214 78.738 4.605 1.00 14.11 ? 481 HIS A C 1 ATOM 3827 O O . HIS A 1 481 ? 41.452 78.708 4.436 1.00 14.68 ? 481 HIS A O 1 ATOM 3828 C CB . HIS A 1 481 ? 39.646 80.776 6.015 1.00 15.04 ? 481 HIS A CB 1 ATOM 3829 C CG . HIS A 1 481 ? 39.495 79.883 7.209 1.00 14.62 ? 481 HIS A CG 1 ATOM 3830 N ND1 . HIS A 1 481 ? 38.276 79.412 7.666 1.00 18.15 ? 481 HIS A ND1 1 ATOM 3831 C CD2 . HIS A 1 481 ? 40.433 79.388 8.059 1.00 15.97 ? 481 HIS A CD2 1 ATOM 3832 C CE1 . HIS A 1 481 ? 38.480 78.674 8.743 1.00 16.97 ? 481 HIS A CE1 1 ATOM 3833 N NE2 . HIS A 1 481 ? 39.776 78.649 9.002 1.00 18.66 ? 481 HIS A NE2 1 ATOM 3834 N N . VAL A 1 482 ? 39.466 77.629 4.704 1.00 12.52 ? 482 VAL A N 1 ATOM 3835 C CA . VAL A 1 482 ? 40.071 76.298 4.627 1.00 13.43 ? 482 VAL A CA 1 ATOM 3836 C C . VAL A 1 482 ? 40.345 75.986 3.156 1.00 12.05 ? 482 VAL A C 1 ATOM 3837 O O . VAL A 1 482 ? 41.404 75.444 2.842 1.00 13.35 ? 482 VAL A O 1 ATOM 3838 C CB . VAL A 1 482 ? 39.117 75.267 5.266 1.00 10.57 ? 482 VAL A CB 1 ATOM 3839 C CG1 . VAL A 1 482 ? 39.773 73.844 5.233 1.00 13.24 ? 482 VAL A CG1 1 ATOM 3840 C CG2 . VAL A 1 482 ? 38.890 75.640 6.768 1.00 12.44 ? 482 VAL A CG2 1 ATOM 3841 N N . VAL A 1 483 ? 39.413 76.348 2.273 1.00 12.39 ? 483 VAL A N 1 ATOM 3842 C CA . VAL A 1 483 ? 39.652 76.168 0.852 1.00 12.17 ? 483 VAL A CA 1 ATOM 3843 C C . VAL A 1 483 ? 40.901 76.976 0.453 1.00 12.91 ? 483 VAL A C 1 ATOM 3844 O O . VAL A 1 483 ? 41.721 76.492 -0.340 1.00 14.06 ? 483 VAL A O 1 ATOM 3845 C CB . VAL A 1 483 ? 38.450 76.681 0.031 1.00 11.09 ? 483 VAL A CB 1 ATOM 3846 C CG1 . VAL A 1 483 ? 38.750 76.644 -1.473 1.00 14.35 ? 483 VAL A CG1 1 ATOM 3847 C CG2 . VAL A 1 483 ? 37.230 75.826 0.338 1.00 14.54 ? 483 VAL A CG2 1 ATOM 3848 N N . VAL A 1 484 ? 41.079 78.182 1.028 1.00 14.45 ? 484 VAL A N 1 ATOM 3849 C CA . VAL A 1 484 ? 42.260 78.998 0.736 1.00 14.36 ? 484 VAL A CA 1 ATOM 3850 C C . VAL A 1 484 ? 43.509 78.270 1.193 1.00 14.97 ? 484 VAL A C 1 ATOM 3851 O O . VAL A 1 484 ? 44.519 78.235 0.461 1.00 15.64 ? 484 VAL A O 1 ATOM 3852 C CB . VAL A 1 484 ? 42.145 80.348 1.416 1.00 14.87 ? 484 VAL A CB 1 ATOM 3853 C CG1 . VAL A 1 484 ? 43.518 81.074 1.356 1.00 17.44 ? 484 VAL A CG1 1 ATOM 3854 C CG2 . VAL A 1 484 ? 41.039 81.142 0.714 1.00 17.47 ? 484 VAL A CG2 1 ATOM 3855 N N . ASP A 1 485 ? 43.440 77.649 2.362 1.00 13.55 ? 485 ASP A N 1 ATOM 3856 C CA . ASP A 1 485 ? 44.598 76.893 2.846 1.00 13.65 ? 485 ASP A CA 1 ATOM 3857 C C . ASP A 1 485 ? 44.939 75.743 1.908 1.00 14.13 ? 485 ASP A C 1 ATOM 3858 O O . ASP A 1 485 ? 46.111 75.528 1.558 1.00 12.73 ? 485 ASP A O 1 ATOM 3859 C CB . ASP A 1 485 ? 44.325 76.367 4.262 1.00 14.59 ? 485 ASP A CB 1 ATOM 3860 C CG . ASP A 1 485 ? 45.560 75.718 4.865 1.00 14.47 ? 485 ASP A CG 1 ATOM 3861 O OD1 . ASP A 1 485 ? 46.595 76.413 4.989 1.00 18.84 ? 485 ASP A OD1 1 ATOM 3862 O OD2 . ASP A 1 485 ? 45.526 74.541 5.224 1.00 15.15 ? 485 ASP A OD2 1 ATOM 3863 N N . TYR A 1 486 ? 43.941 74.979 1.471 1.00 12.06 ? 486 TYR A N 1 ATOM 3864 C CA . TYR A 1 486 ? 44.242 73.892 0.529 1.00 11.90 ? 486 TYR A CA 1 ATOM 3865 C C . TYR A 1 486 ? 44.830 74.432 -0.775 1.00 12.77 ? 486 TYR A C 1 ATOM 3866 O O . TYR A 1 486 ? 45.741 73.786 -1.315 1.00 12.98 ? 486 TYR A O 1 ATOM 3867 C CB . TYR A 1 486 ? 42.981 73.124 0.161 1.00 12.81 ? 486 TYR A CB 1 ATOM 3868 C CG . TYR A 1 486 ? 42.362 72.292 1.287 1.00 11.61 ? 486 TYR A CG 1 ATOM 3869 C CD1 . TYR A 1 486 ? 43.152 71.432 2.076 1.00 13.51 ? 486 TYR A CD1 1 ATOM 3870 C CD2 . TYR A 1 486 ? 40.997 72.343 1.487 1.00 12.92 ? 486 TYR A CD2 1 ATOM 3871 C CE1 . TYR A 1 486 ? 42.536 70.605 3.072 1.00 14.59 ? 486 TYR A CE1 1 ATOM 3872 C CE2 . TYR A 1 486 ? 40.367 71.530 2.465 1.00 11.73 ? 486 TYR A CE2 1 ATOM 3873 C CZ . TYR A 1 486 ? 41.157 70.686 3.225 1.00 13.28 ? 486 TYR A CZ 1 ATOM 3874 O OH . TYR A 1 486 ? 40.508 69.882 4.167 1.00 14.31 ? 486 TYR A OH 1 ATOM 3875 N N . GLU A 1 487 ? 44.298 75.558 -1.276 1.00 12.98 ? 487 GLU A N 1 ATOM 3876 C CA . GLU A 1 487 ? 44.817 76.135 -2.518 1.00 13.48 ? 487 GLU A CA 1 ATOM 3877 C C . GLU A 1 487 ? 46.278 76.572 -2.337 1.00 14.84 ? 487 GLU A C 1 ATOM 3878 O O . GLU A 1 487 ? 47.133 76.320 -3.206 1.00 14.13 ? 487 GLU A O 1 ATOM 3879 C CB . GLU A 1 487 ? 43.956 77.329 -2.933 1.00 13.77 ? 487 GLU A CB 1 ATOM 3880 C CG . GLU A 1 487 ? 44.412 77.906 -4.275 1.00 16.00 ? 487 GLU A CG 1 ATOM 3881 C CD . GLU A 1 487 ? 43.589 79.061 -4.744 1.00 22.00 ? 487 GLU A CD 1 ATOM 3882 O OE1 . GLU A 1 487 ? 42.423 79.217 -4.344 1.00 22.49 ? 487 GLU A OE1 1 ATOM 3883 O OE2 . GLU A 1 487 ? 44.155 79.836 -5.552 1.00 26.54 ? 487 GLU A OE2 1 ATOM 3884 N N . GLN A 1 488 ? 46.573 77.213 -1.218 1.00 15.07 ? 488 GLN A N 1 ATOM 3885 C CA . GLN A 1 488 ? 47.959 77.668 -0.950 1.00 16.40 ? 488 GLN A CA 1 ATOM 3886 C C . GLN A 1 488 ? 48.888 76.488 -0.901 1.00 15.54 ? 488 GLN A C 1 ATOM 3887 O O . GLN A 1 488 ? 49.962 76.515 -1.489 1.00 14.20 ? 488 GLN A O 1 ATOM 3888 C CB . GLN A 1 488 ? 48.047 78.409 0.404 1.00 20.89 ? 488 GLN A CB 1 ATOM 3889 C CG . GLN A 1 488 ? 47.323 79.719 0.379 1.00 28.51 ? 488 GLN A CG 1 ATOM 3890 C CD . GLN A 1 488 ? 47.328 80.434 1.717 1.00 34.88 ? 488 GLN A CD 1 ATOM 3891 O OE1 . GLN A 1 488 ? 46.897 81.580 1.802 1.00 39.88 ? 488 GLN A OE1 1 ATOM 3892 N NE2 . GLN A 1 488 ? 47.807 79.762 2.772 1.00 38.18 ? 488 GLN A NE2 1 ATOM 3893 N N . ARG A 1 489 ? 48.485 75.429 -0.209 1.00 13.18 ? 489 ARG A N 1 ATOM 3894 C CA . ARG A 1 489 ? 49.286 74.214 -0.127 1.00 12.52 ? 489 ARG A CA 1 ATOM 3895 C C . ARG A 1 489 ? 49.503 73.624 -1.512 1.00 12.12 ? 489 ARG A C 1 ATOM 3896 O O . ARG A 1 489 ? 50.624 73.208 -1.861 1.00 13.46 ? 489 ARG A O 1 ATOM 3897 C CB . ARG A 1 489 ? 48.575 73.206 0.759 1.00 13.72 ? 489 ARG A CB 1 ATOM 3898 C CG . ARG A 1 489 ? 48.679 73.565 2.208 1.00 13.14 ? 489 ARG A CG 1 ATOM 3899 C CD . ARG A 1 489 ? 47.687 72.642 2.996 1.00 15.49 ? 489 ARG A CD 1 ATOM 3900 N NE . ARG A 1 489 ? 47.777 72.805 4.465 1.00 13.50 ? 489 ARG A NE 1 ATOM 3901 C CZ . ARG A 1 489 ? 48.652 72.167 5.253 1.00 16.58 ? 489 ARG A CZ 1 ATOM 3902 N NH1 . ARG A 1 489 ? 49.525 71.316 4.762 1.00 17.42 ? 489 ARG A NH1 1 ATOM 3903 N NH2 . ARG A 1 489 ? 48.637 72.399 6.555 1.00 16.14 ? 489 ARG A NH2 1 ATOM 3904 N N . MET A 1 490 ? 48.437 73.580 -2.334 1.00 12.24 ? 490 MET A N 1 ATOM 3905 C CA . MET A 1 490 ? 48.626 73.016 -3.664 1.00 12.31 ? 490 MET A CA 1 ATOM 3906 C C . MET A 1 490 ? 49.512 73.885 -4.544 1.00 12.44 ? 490 MET A C 1 ATOM 3907 O O . MET A 1 490 ? 50.200 73.353 -5.419 1.00 12.89 ? 490 MET A O 1 ATOM 3908 C CB . MET A 1 490 ? 47.290 72.725 -4.359 1.00 13.23 ? 490 MET A CB 1 ATOM 3909 C CG . MET A 1 490 ? 46.534 71.522 -3.688 1.00 13.36 ? 490 MET A CG 1 ATOM 3910 S SD . MET A 1 490 ? 45.229 70.839 -4.783 1.00 15.94 ? 490 MET A SD 1 ATOM 3911 C CE . MET A 1 490 ? 43.961 72.083 -4.397 1.00 17.39 ? 490 MET A CE 1 ATOM 3912 N N . GLN A 1 491 ? 49.487 75.201 -4.365 1.00 13.60 ? 491 GLN A N 1 ATOM 3913 C CA . GLN A 1 491 ? 50.357 76.066 -5.167 1.00 13.62 ? 491 GLN A CA 1 ATOM 3914 C C . GLN A 1 491 ? 51.805 75.774 -4.797 1.00 14.02 ? 491 GLN A C 1 ATOM 3915 O O A GLN A 1 491 ? 52.686 75.639 -5.660 0.50 13.21 ? 491 GLN A O 1 ATOM 3916 O O B GLN A 1 491 ? 52.584 75.900 -5.688 0.50 14.78 ? 491 GLN A O 1 ATOM 3917 C CB A GLN A 1 491 ? 50.051 77.532 -4.887 0.50 16.01 ? 491 GLN A CB 1 ATOM 3918 C CB B GLN A 1 491 ? 49.855 77.540 -4.811 0.50 17.44 ? 491 GLN A CB 1 ATOM 3919 C CG A GLN A 1 491 ? 50.870 78.503 -5.734 0.50 19.94 ? 491 GLN A CG 1 ATOM 3920 C CG B GLN A 1 491 ? 48.958 78.072 -5.900 0.50 23.12 ? 491 GLN A CG 1 ATOM 3921 C CD A GLN A 1 491 ? 50.580 78.380 -7.220 0.50 25.50 ? 491 GLN A CD 1 ATOM 3922 C CD B GLN A 1 491 ? 49.714 78.211 -7.214 0.50 25.44 ? 491 GLN A CD 1 ATOM 3923 O OE1 A GLN A 1 491 ? 51.265 77.652 -7.949 0.50 28.02 ? 491 GLN A OE1 1 ATOM 3924 O OE1 B GLN A 1 491 ? 50.120 77.223 -7.814 0.50 28.47 ? 491 GLN A OE1 1 ATOM 3925 N NE2 A GLN A 1 491 ? 49.552 79.090 -7.677 0.50 32.84 ? 491 GLN A NE2 1 ATOM 3926 N NE2 B GLN A 1 491 ? 49.925 79.453 -7.651 0.50 32.10 ? 491 GLN A NE2 1 ATOM 3927 N N . GLU A 1 492 ? 52.056 75.630 -3.508 1.00 14.50 ? 492 GLU A N 1 ATOM 3928 C CA . GLU A 1 492 ? 53.414 75.320 -3.084 1.00 15.64 ? 492 GLU A CA 1 ATOM 3929 C C . GLU A 1 492 ? 53.831 73.964 -3.674 1.00 14.63 ? 492 GLU A C 1 ATOM 3930 O O . GLU A 1 492 ? 54.970 73.768 -4.131 1.00 15.90 ? 492 GLU A O 1 ATOM 3931 C CB . GLU A 1 492 ? 53.512 75.287 -1.560 1.00 18.71 ? 492 GLU A CB 1 ATOM 3932 C CG . GLU A 1 492 ? 53.464 76.695 -0.918 1.00 25.46 ? 492 GLU A CG 1 ATOM 3933 C CD . GLU A 1 492 ? 54.484 77.668 -1.497 1.00 31.67 ? 492 GLU A CD 1 ATOM 3934 O OE1 . GLU A 1 492 ? 55.695 77.328 -1.556 1.00 35.57 ? 492 GLU A OE1 1 ATOM 3935 O OE2 . GLU A 1 492 ? 54.078 78.791 -1.899 1.00 38.30 ? 492 GLU A OE2 1 ATOM 3936 N N . ALA A 1 493 ? 52.894 73.019 -3.727 1.00 13.24 ? 493 ALA A N 1 ATOM 3937 C CA . ALA A 1 493 ? 53.228 71.727 -4.319 1.00 11.94 ? 493 ALA A CA 1 ATOM 3938 C C . ALA A 1 493 ? 53.533 71.852 -5.825 1.00 12.95 ? 493 ALA A C 1 ATOM 3939 O O . ALA A 1 493 ? 54.405 71.137 -6.326 1.00 11.92 ? 493 ALA A O 1 ATOM 3940 C CB . ALA A 1 493 ? 52.064 70.750 -4.113 1.00 13.98 ? 493 ALA A CB 1 ATOM 3941 N N . LEU A 1 494 ? 52.757 72.688 -6.545 1.00 12.83 ? 494 LEU A N 1 ATOM 3942 C CA . LEU A 1 494 ? 53.024 72.883 -7.974 1.00 12.77 ? 494 LEU A CA 1 ATOM 3943 C C . LEU A 1 494 ? 54.421 73.477 -8.137 1.00 12.34 ? 494 LEU A C 1 ATOM 3944 O O . LEU A 1 494 ? 55.144 73.046 -9.029 1.00 13.65 ? 494 LEU A O 1 ATOM 3945 C CB . LEU A 1 494 ? 51.958 73.815 -8.581 1.00 12.20 ? 494 LEU A CB 1 ATOM 3946 C CG . LEU A 1 494 ? 50.604 73.136 -8.831 1.00 14.43 ? 494 LEU A CG 1 ATOM 3947 C CD1 . LEU A 1 494 ? 49.589 74.250 -9.127 1.00 16.90 ? 494 LEU A CD1 1 ATOM 3948 C CD2 . LEU A 1 494 ? 50.700 72.085 -9.907 1.00 15.50 ? 494 LEU A CD2 1 ATOM 3949 N N . LYS A 1 495 ? 54.805 74.433 -7.292 1.00 14.17 ? 495 LYS A N 1 ATOM 3950 C CA . LYS A 1 495 ? 56.155 75.058 -7.401 1.00 13.78 ? 495 LYS A CA 1 ATOM 3951 C C . LYS A 1 495 ? 57.238 74.003 -7.092 1.00 14.51 ? 495 LYS A C 1 ATOM 3952 O O . LYS A 1 495 ? 58.272 73.935 -7.775 1.00 14.31 ? 495 LYS A O 1 ATOM 3953 C CB . LYS A 1 495 ? 56.266 76.228 -6.449 1.00 17.01 ? 495 LYS A CB 1 ATOM 3954 C CG . LYS A 1 495 ? 55.359 77.368 -6.842 1.00 22.35 ? 495 LYS A CG 1 ATOM 3955 C CD . LYS A 1 495 ? 55.583 78.650 -6.033 1.00 29.78 ? 495 LYS A CD 1 ATOM 3956 C CE . LYS A 1 495 ? 55.221 78.531 -4.581 1.00 35.44 ? 495 LYS A CE 1 ATOM 3957 N NZ . LYS A 1 495 ? 55.253 79.897 -3.903 1.00 39.08 ? 495 LYS A NZ 1 ATOM 3958 N N . ALA A 1 496 ? 56.979 73.111 -6.143 1.00 12.20 ? 496 ALA A N 1 ATOM 3959 C CA . ALA A 1 496 ? 57.934 72.058 -5.853 1.00 12.49 ? 496 ALA A CA 1 ATOM 3960 C C . ALA A 1 496 ? 58.098 71.113 -7.054 1.00 13.64 ? 496 ALA A C 1 ATOM 3961 O O . ALA A 1 496 ? 59.208 70.683 -7.421 1.00 12.15 ? 496 ALA A O 1 ATOM 3962 C CB . ALA A 1 496 ? 57.441 71.285 -4.582 1.00 12.36 ? 496 ALA A CB 1 ATOM 3963 N N . CYS A 1 497 ? 56.978 70.755 -7.690 1.00 11.82 ? 497 CYS A N 1 ATOM 3964 C CA . CYS A 1 497 ? 57.027 69.879 -8.846 1.00 12.35 ? 497 CYS A CA 1 ATOM 3965 C C . CYS A 1 497 ? 57.815 70.561 -9.966 1.00 13.41 ? 497 CYS A C 1 ATOM 3966 O O . CYS A 1 497 ? 58.621 69.921 -10.640 1.00 12.79 ? 497 CYS A O 1 ATOM 3967 C CB . CYS A 1 497 ? 55.617 69.560 -9.346 1.00 10.85 ? 497 CYS A CB 1 ATOM 3968 S SG . CYS A 1 497 ? 54.710 68.405 -8.278 1.00 13.93 ? 497 CYS A SG 1 ATOM 3969 N N . GLN A 1 498 ? 57.511 71.823 -10.220 1.00 11.84 ? 498 GLN A N 1 ATOM 3970 C CA . GLN A 1 498 ? 58.230 72.546 -11.291 1.00 13.00 ? 498 GLN A CA 1 ATOM 3971 C C . GLN A 1 498 ? 59.714 72.526 -11.019 1.00 15.09 ? 498 GLN A C 1 ATOM 3972 O O . GLN A 1 498 ? 60.523 72.280 -11.949 1.00 14.14 ? 498 GLN A O 1 ATOM 3973 C CB . GLN A 1 498 ? 57.754 74.007 -11.363 1.00 13.53 ? 498 GLN A CB 1 ATOM 3974 C CG . GLN A 1 498 ? 58.605 74.830 -12.337 1.00 20.01 ? 498 GLN A CG 1 ATOM 3975 C CD . GLN A 1 498 ? 58.165 76.290 -12.446 1.00 23.29 ? 498 GLN A CD 1 ATOM 3976 O OE1 . GLN A 1 498 ? 58.090 77.029 -11.438 1.00 26.91 ? 498 GLN A OE1 1 ATOM 3977 N NE2 . GLN A 1 498 ? 57.898 76.728 -13.670 1.00 19.12 ? 498 GLN A NE2 1 ATOM 3978 N N . MET A 1 499 ? 60.112 72.789 -9.777 1.00 13.06 ? 499 MET A N 1 ATOM 3979 C CA . MET A 1 499 ? 61.537 72.783 -9.483 1.00 14.07 ? 499 MET A CA 1 ATOM 3980 C C . MET A 1 499 ? 62.184 71.448 -9.775 1.00 12.72 ? 499 MET A C 1 ATOM 3981 O O . MET A 1 499 ? 63.207 71.387 -10.456 1.00 14.03 ? 499 MET A O 1 ATOM 3982 C CB . MET A 1 499 ? 61.756 73.204 -8.024 1.00 13.61 ? 499 MET A CB 1 ATOM 3983 C CG . MET A 1 499 ? 63.174 73.023 -7.458 1.00 16.54 ? 499 MET A CG 1 ATOM 3984 S SD . MET A 1 499 ? 64.445 73.977 -8.310 1.00 21.32 ? 499 MET A SD 1 ATOM 3985 C CE . MET A 1 499 ? 63.937 75.623 -7.854 1.00 19.35 ? 499 MET A CE 1 ATOM 3986 N N . VAL A 1 500 ? 61.549 70.366 -9.331 1.00 12.18 ? 500 VAL A N 1 ATOM 3987 C CA . VAL A 1 500 ? 62.097 69.050 -9.548 1.00 10.77 ? 500 VAL A CA 1 ATOM 3988 C C . VAL A 1 500 ? 62.128 68.739 -11.035 1.00 12.47 ? 500 VAL A C 1 ATOM 3989 O O . VAL A 1 500 ? 63.114 68.187 -11.546 1.00 13.24 ? 500 VAL A O 1 ATOM 3990 C CB . VAL A 1 500 ? 61.300 67.988 -8.743 1.00 13.58 ? 500 VAL A CB 1 ATOM 3991 C CG1 . VAL A 1 500 ? 61.725 66.586 -9.136 1.00 13.87 ? 500 VAL A CG1 1 ATOM 3992 C CG2 . VAL A 1 500 ? 61.586 68.236 -7.263 1.00 14.73 ? 500 VAL A CG2 1 ATOM 3993 N N . MET A 1 501 ? 61.037 69.037 -11.730 1.00 13.15 ? 501 MET A N 1 ATOM 3994 C CA . MET A 1 501 ? 60.970 68.732 -13.154 1.00 13.02 ? 501 MET A CA 1 ATOM 3995 C C . MET A 1 501 ? 62.053 69.463 -13.930 1.00 12.26 ? 501 MET A C 1 ATOM 3996 O O . MET A 1 501 ? 62.727 68.817 -14.766 1.00 12.39 ? 501 MET A O 1 ATOM 3997 C CB . MET A 1 501 ? 59.599 69.113 -13.726 1.00 13.53 ? 501 MET A CB 1 ATOM 3998 C CG . MET A 1 501 ? 58.471 68.168 -13.231 1.00 14.43 ? 501 MET A CG 1 ATOM 3999 S SD . MET A 1 501 ? 56.850 68.839 -13.506 1.00 17.58 ? 501 MET A SD 1 ATOM 4000 C CE . MET A 1 501 ? 56.662 68.604 -15.269 1.00 17.02 ? 501 MET A CE 1 ATOM 4001 N N . GLN A 1 502 ? 62.211 70.765 -13.686 1.00 13.68 ? 502 GLN A N 1 ATOM 4002 C CA . GLN A 1 502 ? 63.176 71.503 -14.507 1.00 13.39 ? 502 GLN A CA 1 ATOM 4003 C C . GLN A 1 502 ? 64.616 71.120 -14.172 1.00 14.50 ? 502 GLN A C 1 ATOM 4004 O O . GLN A 1 502 ? 65.445 71.040 -15.096 1.00 14.24 ? 502 GLN A O 1 ATOM 4005 C CB . GLN A 1 502 ? 62.890 73.000 -14.447 1.00 15.64 ? 502 GLN A CB 1 ATOM 4006 C CG . GLN A 1 502 ? 63.069 73.633 -13.085 1.00 15.05 ? 502 GLN A CG 1 ATOM 4007 C CD . GLN A 1 502 ? 64.487 74.163 -12.858 1.00 18.65 ? 502 GLN A CD 1 ATOM 4008 O OE1 . GLN A 1 502 ? 65.286 74.268 -13.805 1.00 16.37 ? 502 GLN A OE1 1 ATOM 4009 N NE2 . GLN A 1 502 ? 64.803 74.518 -11.626 1.00 17.54 ? 502 GLN A NE2 1 ATOM 4010 N N . GLN A 1 503 ? 64.919 70.834 -12.915 1.00 13.62 ? 503 GLN A N 1 ATOM 4011 C CA . GLN A 1 503 ? 66.282 70.334 -12.624 1.00 14.39 ? 503 GLN A CA 1 ATOM 4012 C C . GLN A 1 503 ? 66.512 69.005 -13.341 1.00 14.10 ? 503 GLN A C 1 ATOM 4013 O O . GLN A 1 503 ? 67.618 68.730 -13.847 1.00 15.64 ? 503 GLN A O 1 ATOM 4014 C CB . GLN A 1 503 ? 66.470 70.104 -11.119 1.00 14.79 ? 503 GLN A CB 1 ATOM 4015 C CG . GLN A 1 503 ? 66.588 71.391 -10.335 1.00 15.97 ? 503 GLN A CG 1 ATOM 4016 C CD . GLN A 1 503 ? 67.963 72.060 -10.468 1.00 17.07 ? 503 GLN A CD 1 ATOM 4017 O OE1 . GLN A 1 503 ? 68.942 71.397 -10.771 1.00 20.20 ? 503 GLN A OE1 1 ATOM 4018 N NE2 . GLN A 1 503 ? 68.027 73.353 -10.198 1.00 19.40 ? 503 GLN A NE2 1 ATOM 4019 N N . SER A 1 504 ? 65.488 68.138 -13.386 1.00 13.62 ? 504 SER A N 1 ATOM 4020 C CA . SER A 1 504 ? 65.634 66.855 -14.043 1.00 14.64 ? 504 SER A CA 1 ATOM 4021 C C . SER A 1 504 ? 65.857 66.999 -15.554 1.00 13.83 ? 504 SER A C 1 ATOM 4022 O O . SER A 1 504 ? 66.711 66.296 -16.136 1.00 14.56 ? 504 SER A O 1 ATOM 4023 C CB . SER A 1 504 ? 64.394 65.962 -13.793 1.00 15.43 ? 504 SER A CB 1 ATOM 4024 O OG . SER A 1 504 ? 64.224 65.725 -12.382 1.00 14.14 ? 504 SER A OG 1 ATOM 4025 N N . VAL A 1 505 ? 65.071 67.865 -16.205 1.00 13.68 ? 505 VAL A N 1 ATOM 4026 C CA . VAL A 1 505 ? 65.230 68.066 -17.654 1.00 14.28 ? 505 VAL A CA 1 ATOM 4027 C C . VAL A 1 505 ? 66.660 68.587 -17.960 1.00 13.42 ? 505 VAL A C 1 ATOM 4028 O O . VAL A 1 505 ? 67.330 68.120 -18.893 1.00 14.95 ? 505 VAL A O 1 ATOM 4029 C CB . VAL A 1 505 ? 64.156 69.065 -18.155 1.00 13.80 ? 505 VAL A CB 1 ATOM 4030 C CG1 . VAL A 1 505 ? 64.498 69.553 -19.582 1.00 14.41 ? 505 VAL A CG1 1 ATOM 4031 C CG2 . VAL A 1 505 ? 62.771 68.400 -18.109 1.00 14.47 ? 505 VAL A CG2 1 ATOM 4032 N N . TYR A 1 506 ? 67.141 69.498 -17.156 1.00 13.77 ? 506 TYR A N 1 ATOM 4033 C CA . TYR A 1 506 ? 68.473 70.031 -17.377 1.00 14.83 ? 506 TYR A CA 1 ATOM 4034 C C . TYR A 1 506 ? 69.520 68.901 -17.268 1.00 16.79 ? 506 TYR A C 1 ATOM 4035 O O . TYR A 1 506 ? 70.440 68.790 -18.086 1.00 16.69 ? 506 TYR A O 1 ATOM 4036 C CB . TYR A 1 506 ? 68.769 71.130 -16.366 1.00 16.01 ? 506 TYR A CB 1 ATOM 4037 C CG . TYR A 1 506 ? 70.041 71.839 -16.662 1.00 20.78 ? 506 TYR A CG 1 ATOM 4038 C CD1 . TYR A 1 506 ? 70.213 72.450 -17.907 1.00 23.66 ? 506 TYR A CD1 1 ATOM 4039 C CD2 . TYR A 1 506 ? 71.067 71.874 -15.732 1.00 20.77 ? 506 TYR A CD2 1 ATOM 4040 C CE1 . TYR A 1 506 ? 71.375 73.078 -18.219 1.00 26.76 ? 506 TYR A CE1 1 ATOM 4041 C CE2 . TYR A 1 506 ? 72.278 72.517 -16.043 1.00 25.87 ? 506 TYR A CE2 1 ATOM 4042 C CZ . TYR A 1 506 ? 72.395 73.112 -17.294 1.00 25.60 ? 506 TYR A CZ 1 ATOM 4043 O OH . TYR A 1 506 ? 73.507 73.827 -17.664 1.00 29.85 ? 506 TYR A OH 1 ATOM 4044 N N . ARG A 1 507 ? 69.348 68.010 -16.303 1.00 16.23 ? 507 ARG A N 1 ATOM 4045 C CA . ARG A 1 507 ? 70.301 66.906 -16.143 1.00 15.91 ? 507 ARG A CA 1 ATOM 4046 C C . ARG A 1 507 ? 70.181 65.870 -17.256 1.00 16.70 ? 507 ARG A C 1 ATOM 4047 O O . ARG A 1 507 ? 71.197 65.326 -17.747 1.00 16.63 ? 507 ARG A O 1 ATOM 4048 C CB . ARG A 1 507 ? 70.075 66.242 -14.787 1.00 16.38 ? 507 ARG A CB 1 ATOM 4049 C CG . ARG A 1 507 ? 71.148 65.199 -14.457 1.00 16.85 ? 507 ARG A CG 1 ATOM 4050 C CD . ARG A 1 507 ? 71.035 64.789 -12.999 1.00 18.29 ? 507 ARG A CD 1 ATOM 4051 N NE . ARG A 1 507 ? 72.063 63.795 -12.651 1.00 21.88 ? 507 ARG A NE 1 ATOM 4052 C CZ . ARG A 1 507 ? 72.129 63.196 -11.455 1.00 22.26 ? 507 ARG A CZ 1 ATOM 4053 N NH1 . ARG A 1 507 ? 71.251 63.486 -10.502 1.00 22.19 ? 507 ARG A NH1 1 ATOM 4054 N NH2 . ARG A 1 507 ? 73.048 62.266 -11.217 1.00 23.02 ? 507 ARG A NH2 1 ATOM 4055 N N . LEU A 1 508 ? 68.946 65.582 -17.671 1.00 15.02 ? 508 LEU A N 1 ATOM 4056 C CA . LEU A 1 508 ? 68.742 64.599 -18.695 1.00 14.98 ? 508 LEU A CA 1 ATOM 4057 C C . LEU A 1 508 ? 69.168 65.005 -20.102 1.00 14.20 ? 508 LEU A C 1 ATOM 4058 O O . LEU A 1 508 ? 69.412 64.145 -20.952 1.00 17.60 ? 508 LEU A O 1 ATOM 4059 C CB . LEU A 1 508 ? 67.275 64.176 -18.738 1.00 14.74 ? 508 LEU A CB 1 ATOM 4060 C CG . LEU A 1 508 ? 66.799 63.378 -17.517 1.00 15.19 ? 508 LEU A CG 1 ATOM 4061 C CD1 . LEU A 1 508 ? 65.249 63.501 -17.421 1.00 15.09 ? 508 LEU A CD1 1 ATOM 4062 C CD2 . LEU A 1 508 ? 67.258 61.925 -17.670 1.00 16.25 ? 508 LEU A CD2 1 ATOM 4063 N N . LEU A 1 509 ? 69.231 66.317 -20.336 1.00 15.71 ? 509 LEU A N 1 ATOM 4064 C CA . LEU A 1 509 ? 69.533 66.812 -21.669 1.00 15.95 ? 509 LEU A CA 1 ATOM 4065 C C . LEU A 1 509 ? 70.803 67.638 -21.763 1.00 17.20 ? 509 LEU A C 1 ATOM 4066 O O . LEU A 1 509 ? 70.961 68.401 -22.721 1.00 17.09 ? 509 LEU A O 1 ATOM 4067 C CB . LEU A 1 509 ? 68.318 67.605 -22.193 1.00 15.68 ? 509 LEU A CB 1 ATOM 4068 C CG . LEU A 1 509 ? 67.098 66.744 -22.526 1.00 13.63 ? 509 LEU A CG 1 ATOM 4069 C CD1 . LEU A 1 509 ? 65.970 67.711 -22.930 1.00 13.27 ? 509 LEU A CD1 1 ATOM 4070 C CD2 . LEU A 1 509 ? 67.351 65.733 -23.674 1.00 16.64 ? 509 LEU A CD2 1 ATOM 4071 N N . THR A 1 510 ? 71.715 67.511 -20.812 1.00 15.61 ? 510 THR A N 1 ATOM 4072 C CA . THR A 1 510 ? 72.958 68.261 -20.910 1.00 17.18 ? 510 THR A CA 1 ATOM 4073 C C . THR A 1 510 ? 74.123 67.273 -20.910 1.00 17.56 ? 510 THR A C 1 ATOM 4074 O O . THR A 1 510 ? 74.120 66.300 -20.159 1.00 17.41 ? 510 THR A O 1 ATOM 4075 C CB . THR A 1 510 ? 73.099 69.231 -19.750 1.00 15.52 ? 510 THR A CB 1 ATOM 4076 O OG1 . THR A 1 510 ? 71.995 70.150 -19.780 1.00 16.23 ? 510 THR A OG1 1 ATOM 4077 C CG2 . THR A 1 510 ? 74.423 70.070 -19.841 1.00 17.62 ? 510 THR A CG2 1 ATOM 4078 N N . LYS A 1 511 ? 75.084 67.501 -21.807 1.00 18.31 ? 511 LYS A N 1 ATOM 4079 C CA . LYS A 1 511 ? 76.243 66.625 -21.898 1.00 19.29 ? 511 LYS A CA 1 ATOM 4080 C C . LYS A 1 511 ? 76.766 66.470 -20.484 1.00 19.31 ? 511 LYS A C 1 ATOM 4081 O O . LYS A 1 511 ? 77.024 67.438 -19.767 1.00 19.55 ? 511 LYS A O 1 ATOM 4082 C CB . LYS A 1 511 ? 77.316 67.260 -22.798 1.00 21.99 ? 511 LYS A CB 1 ATOM 4083 C CG . LYS A 1 511 ? 78.562 66.403 -22.819 1.00 27.23 ? 511 LYS A CG 1 ATOM 4084 C CD . LYS A 1 511 ? 79.539 66.768 -23.905 1.00 31.92 ? 511 LYS A CD 1 ATOM 4085 C CE . LYS A 1 511 ? 80.634 65.684 -23.947 1.00 36.46 ? 511 LYS A CE 1 ATOM 4086 N NZ . LYS A 1 511 ? 81.806 66.047 -24.798 1.00 38.12 ? 511 LYS A NZ 1 ATOM 4087 N N . PRO A 1 512 ? 76.966 65.217 -20.059 1.00 20.50 ? 512 PRO A N 1 ATOM 4088 C CA . PRO A 1 512 ? 77.443 64.941 -18.713 1.00 22.26 ? 512 PRO A CA 1 ATOM 4089 C C . PRO A 1 512 ? 78.669 65.680 -18.216 1.00 20.44 ? 512 PRO A C 1 ATOM 4090 O O . PRO A 1 512 ? 78.679 66.171 -17.091 1.00 20.15 ? 512 PRO A O 1 ATOM 4091 C CB . PRO A 1 512 ? 77.639 63.428 -18.731 1.00 24.06 ? 512 PRO A CB 1 ATOM 4092 C CG . PRO A 1 512 ? 76.600 62.980 -19.662 1.00 25.84 ? 512 PRO A CG 1 ATOM 4093 C CD . PRO A 1 512 ? 76.687 63.971 -20.790 1.00 23.11 ? 512 PRO A CD 1 ATOM 4094 N N . SER A 1 513 ? 79.697 65.786 -19.060 1.00 21.41 ? 513 SER A N 1 ATOM 4095 C CA . SER A 1 513 ? 80.921 66.465 -18.613 1.00 21.76 ? 513 SER A CA 1 ATOM 4096 C C . SER A 1 513 ? 80.793 67.972 -18.565 1.00 20.32 ? 513 SER A C 1 ATOM 4097 O O . SER A 1 513 ? 81.734 68.653 -18.135 1.00 23.21 ? 513 SER A O 1 ATOM 4098 C CB . SER A 1 513 ? 82.117 66.071 -19.498 1.00 20.96 ? 513 SER A CB 1 ATOM 4099 O OG . SER A 1 513 ? 81.813 66.300 -20.847 1.00 23.96 ? 513 SER A OG 1 ATOM 4100 N N . ILE A 1 514 ? 79.648 68.512 -18.990 1.00 20.20 ? 514 ILE A N 1 ATOM 4101 C CA . ILE A 1 514 ? 79.402 69.955 -18.958 1.00 20.47 ? 514 ILE A CA 1 ATOM 4102 C C . ILE A 1 514 ? 78.405 70.301 -17.830 1.00 19.55 ? 514 ILE A C 1 ATOM 4103 O O . ILE A 1 514 ? 78.427 71.392 -17.260 1.00 19.77 ? 514 ILE A O 1 ATOM 4104 C CB . ILE A 1 514 ? 78.784 70.433 -20.307 1.00 22.61 ? 514 ILE A CB 1 ATOM 4105 C CG1 . ILE A 1 514 ? 79.835 70.367 -21.420 1.00 25.34 ? 514 ILE A CG1 1 ATOM 4106 C CG2 . ILE A 1 514 ? 78.176 71.863 -20.154 1.00 22.76 ? 514 ILE A CG2 1 ATOM 4107 C CD1 . ILE A 1 514 ? 79.293 70.752 -22.768 1.00 27.99 ? 514 ILE A CD1 1 ATOM 4108 N N . TYR A 1 515 ? 77.531 69.344 -17.512 1.00 18.88 ? 515 TYR A N 1 ATOM 4109 C CA . TYR A 1 515 ? 76.491 69.551 -16.491 1.00 16.81 ? 515 TYR A CA 1 ATOM 4110 C C . TYR A 1 515 ? 77.043 70.122 -15.194 1.00 18.31 ? 515 TYR A C 1 ATOM 4111 O O . TYR A 1 515 ? 77.896 69.497 -14.572 1.00 19.10 ? 515 TYR A O 1 ATOM 4112 C CB . TYR A 1 515 ? 75.785 68.200 -16.287 1.00 17.67 ? 515 TYR A CB 1 ATOM 4113 C CG . TYR A 1 515 ? 74.761 68.189 -15.203 1.00 18.68 ? 515 TYR A CG 1 ATOM 4114 C CD1 . TYR A 1 515 ? 73.592 68.936 -15.301 1.00 17.26 ? 515 TYR A CD1 1 ATOM 4115 C CD2 . TYR A 1 515 ? 74.955 67.394 -14.098 1.00 18.97 ? 515 TYR A CD2 1 ATOM 4116 C CE1 . TYR A 1 515 ? 72.612 68.880 -14.295 1.00 18.69 ? 515 TYR A CE1 1 ATOM 4117 C CE2 . TYR A 1 515 ? 74.005 67.325 -13.083 1.00 17.80 ? 515 TYR A CE2 1 ATOM 4118 C CZ . TYR A 1 515 ? 72.839 68.071 -13.198 1.00 18.93 ? 515 TYR A CZ 1 ATOM 4119 O OH . TYR A 1 515 ? 71.887 67.961 -12.224 1.00 18.25 ? 515 TYR A OH 1 ATOM 4120 N N . SER A 1 516 ? 76.570 71.299 -14.773 1.00 18.19 ? 516 SER A N 1 ATOM 4121 C CA . SER A 1 516 ? 77.088 71.965 -13.557 1.00 19.18 ? 516 SER A CA 1 ATOM 4122 C C . SER A 1 516 ? 75.913 72.621 -12.833 1.00 19.50 ? 516 SER A C 1 ATOM 4123 O O . SER A 1 516 ? 75.753 73.854 -12.813 1.00 22.02 ? 516 SER A O 1 ATOM 4124 C CB . SER A 1 516 ? 78.113 73.048 -13.959 1.00 20.60 ? 516 SER A CB 1 ATOM 4125 O OG . SER A 1 516 ? 78.810 73.490 -12.802 1.00 25.39 ? 516 SER A OG 1 ATOM 4126 N N . PRO A 1 517 ? 75.096 71.800 -12.167 1.00 20.38 ? 517 PRO A N 1 ATOM 4127 C CA . PRO A 1 517 ? 73.937 72.371 -11.500 1.00 21.75 ? 517 PRO A CA 1 ATOM 4128 C C . PRO A 1 517 ? 74.029 73.213 -10.268 1.00 20.94 ? 517 PRO A C 1 ATOM 4129 O O . PRO A 1 517 ? 74.856 72.974 -9.393 1.00 25.37 ? 517 PRO A O 1 ATOM 4130 C CB . PRO A 1 517 ? 73.065 71.145 -11.240 1.00 20.83 ? 517 PRO A CB 1 ATOM 4131 C CG . PRO A 1 517 ? 74.100 70.126 -10.877 1.00 21.64 ? 517 PRO A CG 1 ATOM 4132 C CD . PRO A 1 517 ? 75.199 70.353 -11.942 1.00 21.11 ? 517 PRO A CD 1 ATOM 4133 N N . ASP A 1 518 ? 73.182 74.230 -10.225 1.00 22.42 ? 518 ASP A N 1 ATOM 4134 C CA . ASP A 1 518 ? 72.997 75.042 -9.033 1.00 23.51 ? 518 ASP A CA 1 ATOM 4135 C C . ASP A 1 518 ? 71.555 74.577 -8.733 1.00 22.53 ? 518 ASP A C 1 ATOM 4136 O O . ASP A 1 518 ? 70.600 74.890 -9.486 1.00 21.99 ? 518 ASP A O 1 ATOM 4137 C CB . ASP A 1 518 ? 73.015 76.526 -9.350 1.00 25.39 ? 518 ASP A CB 1 ATOM 4138 C CG . ASP A 1 518 ? 72.510 77.370 -8.198 1.00 29.30 ? 518 ASP A CG 1 ATOM 4139 O OD1 . ASP A 1 518 ? 71.918 76.826 -7.229 1.00 25.93 ? 518 ASP A OD1 1 ATOM 4140 O OD2 . ASP A 1 518 ? 72.684 78.597 -8.275 1.00 31.63 ? 518 ASP A OD2 1 ATOM 4141 N N . PHE A 1 519 ? 71.421 73.804 -7.661 1.00 22.55 ? 519 PHE A N 1 ATOM 4142 C CA . PHE A 1 519 ? 70.126 73.221 -7.327 1.00 21.10 ? 519 PHE A CA 1 ATOM 4143 C C . PHE A 1 519 ? 69.046 74.190 -6.922 1.00 21.07 ? 519 PHE A C 1 ATOM 4144 O O . PHE A 1 519 ? 67.911 73.785 -6.736 1.00 22.94 ? 519 PHE A O 1 ATOM 4145 C CB . PHE A 1 519 ? 70.304 72.146 -6.279 1.00 20.26 ? 519 PHE A CB 1 ATOM 4146 C CG . PHE A 1 519 ? 71.171 71.007 -6.724 1.00 19.84 ? 519 PHE A CG 1 ATOM 4147 C CD1 . PHE A 1 519 ? 70.884 70.314 -7.897 1.00 19.99 ? 519 PHE A CD1 1 ATOM 4148 C CD2 . PHE A 1 519 ? 72.276 70.628 -5.959 1.00 19.83 ? 519 PHE A CD2 1 ATOM 4149 C CE1 . PHE A 1 519 ? 71.677 69.261 -8.317 1.00 20.22 ? 519 PHE A CE1 1 ATOM 4150 C CE2 . PHE A 1 519 ? 73.081 69.579 -6.353 1.00 18.85 ? 519 PHE A CE2 1 ATOM 4151 C CZ . PHE A 1 519 ? 72.792 68.884 -7.532 1.00 20.90 ? 519 PHE A CZ 1 ATOM 4152 N N . SER A 1 520 ? 69.381 75.466 -6.785 1.00 20.02 ? 520 SER A N 1 ATOM 4153 C CA . SER A 1 520 ? 68.391 76.481 -6.437 1.00 20.71 ? 520 SER A CA 1 ATOM 4154 C C . SER A 1 520 ? 68.025 77.292 -7.712 1.00 22.10 ? 520 SER A C 1 ATOM 4155 O O . SER A 1 520 ? 67.097 78.089 -7.699 1.00 21.91 ? 520 SER A O 1 ATOM 4156 C CB . SER A 1 520 ? 68.979 77.449 -5.411 1.00 22.94 ? 520 SER A CB 1 ATOM 4157 O OG . SER A 1 520 ? 70.020 78.223 -6.006 1.00 27.30 ? 520 SER A OG 1 ATOM 4158 N N . PHE A 1 521 ? 68.722 77.032 -8.816 1.00 21.34 ? 521 PHE A N 1 ATOM 4159 C CA . PHE A 1 521 ? 68.509 77.807 -10.034 1.00 22.35 ? 521 PHE A CA 1 ATOM 4160 C C . PHE A 1 521 ? 67.391 77.308 -10.949 1.00 20.83 ? 521 PHE A C 1 ATOM 4161 O O . PHE A 1 521 ? 67.129 76.113 -11.019 1.00 21.13 ? 521 PHE A O 1 ATOM 4162 C CB . PHE A 1 521 ? 69.841 77.829 -10.802 1.00 23.24 ? 521 PHE A CB 1 ATOM 4163 C CG . PHE A 1 521 ? 69.859 78.779 -11.981 1.00 25.23 ? 521 PHE A CG 1 ATOM 4164 C CD1 . PHE A 1 521 ? 70.063 80.140 -11.784 1.00 28.29 ? 521 PHE A CD1 1 ATOM 4165 C CD2 . PHE A 1 521 ? 69.644 78.308 -13.279 1.00 26.04 ? 521 PHE A CD2 1 ATOM 4166 C CE1 . PHE A 1 521 ? 70.042 81.024 -12.865 1.00 29.70 ? 521 PHE A CE1 1 ATOM 4167 C CE2 . PHE A 1 521 ? 69.625 79.183 -14.358 1.00 27.45 ? 521 PHE A CE2 1 ATOM 4168 C CZ . PHE A 1 521 ? 69.822 80.545 -14.154 1.00 29.33 ? 521 PHE A CZ 1 ATOM 4169 N N . SER A 1 522 ? 66.775 78.239 -11.673 1.00 20.79 ? 522 SER A N 1 ATOM 4170 C CA . SER A 1 522 ? 65.721 77.905 -12.612 1.00 20.93 ? 522 SER A CA 1 ATOM 4171 C C . SER A 1 522 ? 66.277 77.823 -14.025 1.00 19.62 ? 522 SER A C 1 ATOM 4172 O O . SER A 1 522 ? 66.352 78.818 -14.711 1.00 21.59 ? 522 SER A O 1 ATOM 4173 C CB . SER A 1 522 ? 64.620 78.964 -12.574 1.00 24.71 ? 522 SER A CB 1 ATOM 4174 O OG . SER A 1 522 ? 63.810 78.736 -11.431 1.00 33.90 ? 522 SER A OG 1 ATOM 4175 N N . TYR A 1 523 ? 66.630 76.632 -14.461 1.00 15.31 ? 523 TYR A N 1 ATOM 4176 C CA . TYR A 1 523 ? 67.154 76.443 -15.810 1.00 14.52 ? 523 TYR A CA 1 ATOM 4177 C C . TYR A 1 523 ? 66.019 76.500 -16.825 1.00 17.11 ? 523 TYR A C 1 ATOM 4178 O O . TYR A 1 523 ? 66.243 76.889 -17.962 1.00 15.81 ? 523 TYR A O 1 ATOM 4179 C CB . TYR A 1 523 ? 67.842 75.088 -15.918 1.00 16.53 ? 523 TYR A CB 1 ATOM 4180 C CG . TYR A 1 523 ? 69.103 75.061 -15.131 1.00 19.08 ? 523 TYR A CG 1 ATOM 4181 C CD1 . TYR A 1 523 ? 70.265 75.686 -15.621 1.00 20.36 ? 523 TYR A CD1 1 ATOM 4182 C CD2 . TYR A 1 523 ? 69.135 74.486 -13.871 1.00 17.57 ? 523 TYR A CD2 1 ATOM 4183 C CE1 . TYR A 1 523 ? 71.420 75.732 -14.857 1.00 21.86 ? 523 TYR A CE1 1 ATOM 4184 C CE2 . TYR A 1 523 ? 70.280 74.529 -13.118 1.00 20.78 ? 523 TYR A CE2 1 ATOM 4185 C CZ . TYR A 1 523 ? 71.412 75.159 -13.622 1.00 24.55 ? 523 TYR A CZ 1 ATOM 4186 O OH . TYR A 1 523 ? 72.568 75.232 -12.874 1.00 24.57 ? 523 TYR A OH 1 ATOM 4187 N N . PHE A 1 524 ? 64.812 76.103 -16.413 1.00 15.20 ? 524 PHE A N 1 ATOM 4188 C CA . PHE A 1 524 ? 63.635 76.143 -17.285 1.00 14.60 ? 524 PHE A CA 1 ATOM 4189 C C . PHE A 1 524 ? 62.436 76.586 -16.485 1.00 17.65 ? 524 PHE A C 1 ATOM 4190 O O . PHE A 1 524 ? 62.396 76.392 -15.281 1.00 17.56 ? 524 PHE A O 1 ATOM 4191 C CB . PHE A 1 524 ? 63.235 74.768 -17.838 1.00 14.91 ? 524 PHE A CB 1 ATOM 4192 C CG . PHE A 1 524 ? 64.271 74.115 -18.690 1.00 14.32 ? 524 PHE A CG 1 ATOM 4193 C CD1 . PHE A 1 524 ? 65.307 73.367 -18.102 1.00 16.06 ? 524 PHE A CD1 1 ATOM 4194 C CD2 . PHE A 1 524 ? 64.236 74.232 -20.078 1.00 15.24 ? 524 PHE A CD2 1 ATOM 4195 C CE1 . PHE A 1 524 ? 66.278 72.768 -18.908 1.00 16.46 ? 524 PHE A CE1 1 ATOM 4196 C CE2 . PHE A 1 524 ? 65.200 73.632 -20.875 1.00 15.13 ? 524 PHE A CE2 1 ATOM 4197 C CZ . PHE A 1 524 ? 66.232 72.896 -20.277 1.00 16.14 ? 524 PHE A CZ 1 ATOM 4198 N N . THR A 1 525 ? 61.489 77.208 -17.154 1.00 17.71 ? 525 THR A N 1 ATOM 4199 C CA . THR A 1 525 ? 60.237 77.478 -16.471 1.00 20.09 ? 525 THR A CA 1 ATOM 4200 C C . THR A 1 525 ? 59.194 76.685 -17.247 1.00 17.02 ? 525 THR A C 1 ATOM 4201 O O . THR A 1 525 ? 59.281 76.506 -18.487 1.00 20.20 ? 525 THR A O 1 ATOM 4202 C CB . THR A 1 525 ? 59.826 78.924 -16.487 1.00 23.37 ? 525 THR A CB 1 ATOM 4203 O OG1 . THR A 1 525 ? 59.773 79.362 -17.825 1.00 25.09 ? 525 THR A OG1 1 ATOM 4204 C CG2 . THR A 1 525 ? 60.832 79.805 -15.729 1.00 25.08 ? 525 THR A CG2 1 ATOM 4205 N N . LEU A 1 526 ? 58.221 76.163 -16.526 1.00 16.56 ? 526 LEU A N 1 ATOM 4206 C CA . LEU A 1 526 ? 57.136 75.439 -17.144 1.00 16.99 ? 526 LEU A CA 1 ATOM 4207 C C . LEU A 1 526 ? 56.166 76.413 -17.811 1.00 18.04 ? 526 LEU A C 1 ATOM 4208 O O . LEU A 1 526 ? 55.924 77.515 -17.305 1.00 21.38 ? 526 LEU A O 1 ATOM 4209 C CB . LEU A 1 526 ? 56.374 74.629 -16.087 1.00 21.82 ? 526 LEU A CB 1 ATOM 4210 C CG . LEU A 1 526 ? 56.900 73.258 -15.699 1.00 20.75 ? 526 LEU A CG 1 ATOM 4211 C CD1 . LEU A 1 526 ? 56.070 72.756 -14.520 1.00 25.42 ? 526 LEU A CD1 1 ATOM 4212 C CD2 . LEU A 1 526 ? 56.804 72.295 -16.871 1.00 22.01 ? 526 LEU A CD2 1 ATOM 4213 N N . ASP A 1 527 ? 55.634 76.020 -18.951 1.00 15.18 ? 527 ASP A N 1 ATOM 4214 C CA . ASP A 1 527 ? 54.633 76.822 -19.655 1.00 15.56 ? 527 ASP A CA 1 ATOM 4215 C C . ASP A 1 527 ? 53.394 75.930 -19.710 1.00 15.95 ? 527 ASP A C 1 ATOM 4216 O O . ASP A 1 527 ? 53.453 74.808 -20.183 1.00 19.65 ? 527 ASP A O 1 ATOM 4217 C CB . ASP A 1 527 ? 55.085 77.198 -21.081 1.00 18.24 ? 527 ASP A CB 1 ATOM 4218 C CG . ASP A 1 527 ? 54.046 78.047 -21.804 1.00 19.59 ? 527 ASP A CG 1 ATOM 4219 O OD1 . ASP A 1 527 ? 53.796 79.171 -21.365 1.00 21.78 ? 527 ASP A OD1 1 ATOM 4220 O OD2 . ASP A 1 527 ? 53.479 77.561 -22.799 1.00 21.81 ? 527 ASP A OD2 1 ATOM 4221 N N . ASP A 1 528 ? 52.301 76.409 -19.134 1.00 15.56 ? 528 ASP A N 1 ATOM 4222 C CA . ASP A 1 528 ? 51.072 75.611 -19.107 1.00 15.23 ? 528 ASP A CA 1 ATOM 4223 C C . ASP A 1 528 ? 49.969 76.469 -19.711 1.00 16.78 ? 528 ASP A C 1 ATOM 4224 O O . ASP A 1 528 ? 49.643 77.541 -19.184 1.00 17.54 ? 528 ASP A O 1 ATOM 4225 C CB . ASP A 1 528 ? 50.738 75.237 -17.655 1.00 16.04 ? 528 ASP A CB 1 ATOM 4226 C CG . ASP A 1 528 ? 49.683 74.129 -17.566 1.00 18.07 ? 528 ASP A CG 1 ATOM 4227 O OD1 . ASP A 1 528 ? 48.661 74.169 -18.289 1.00 17.00 ? 528 ASP A OD1 1 ATOM 4228 O OD2 . ASP A 1 528 ? 49.884 73.170 -16.780 1.00 18.82 ? 528 ASP A OD2 1 ATOM 4229 N N . SER A 1 529 ? 49.431 75.979 -20.820 1.00 17.74 ? 529 SER A N 1 ATOM 4230 C CA . SER A 1 529 ? 48.369 76.672 -21.567 1.00 17.55 ? 529 SER A CA 1 ATOM 4231 C C . SER A 1 529 ? 46.992 76.546 -20.976 1.00 19.92 ? 529 SER A C 1 ATOM 4232 O O . SER A 1 529 ? 46.112 77.300 -21.338 1.00 23.42 ? 529 SER A O 1 ATOM 4233 C CB . SER A 1 529 ? 48.255 76.126 -22.998 1.00 23.07 ? 529 SER A CB 1 ATOM 4234 O OG . SER A 1 529 ? 49.489 76.229 -23.636 1.00 25.36 ? 529 SER A OG 1 ATOM 4235 N N . ARG A 1 530 ? 46.788 75.596 -20.072 1.00 16.91 ? 530 ARG A N 1 ATOM 4236 C CA . ARG A 1 530 ? 45.452 75.393 -19.551 1.00 19.02 ? 530 ARG A CA 1 ATOM 4237 C C . ARG A 1 530 ? 45.316 75.532 -18.071 1.00 20.41 ? 530 ARG A C 1 ATOM 4238 O O . ARG A 1 530 ? 44.254 75.205 -17.513 1.00 24.09 ? 530 ARG A O 1 ATOM 4239 C CB . ARG A 1 530 ? 44.932 74.027 -19.993 1.00 17.17 ? 530 ARG A CB 1 ATOM 4240 C CG . ARG A 1 530 ? 44.950 73.925 -21.507 1.00 19.96 ? 530 ARG A CG 1 ATOM 4241 C CD . ARG A 1 530 ? 44.289 72.687 -22.069 1.00 21.04 ? 530 ARG A CD 1 ATOM 4242 N NE . ARG A 1 530 ? 44.979 71.495 -21.610 1.00 20.77 ? 530 ARG A NE 1 ATOM 4243 C CZ . ARG A 1 530 ? 44.789 70.304 -22.155 1.00 21.95 ? 530 ARG A CZ 1 ATOM 4244 N NH1 . ARG A 1 530 ? 43.933 70.178 -23.171 1.00 22.03 ? 530 ARG A NH1 1 ATOM 4245 N NH2 . ARG A 1 530 ? 45.443 69.267 -21.688 1.00 19.77 ? 530 ARG A NH2 1 ATOM 4246 N N . TRP A 1 531 ? 46.376 75.952 -17.389 1.00 17.07 ? 531 TRP A N 1 ATOM 4247 C CA . TRP A 1 531 ? 46.224 76.170 -15.935 1.00 16.11 ? 531 TRP A CA 1 ATOM 4248 C C . TRP A 1 531 ? 47.155 77.302 -15.515 1.00 16.55 ? 531 TRP A C 1 ATOM 4249 O O . TRP A 1 531 ? 48.343 77.219 -15.751 1.00 18.26 ? 531 TRP A O 1 ATOM 4250 C CB . TRP A 1 531 ? 46.600 74.925 -15.108 1.00 17.46 ? 531 TRP A CB 1 ATOM 4251 C CG . TRP A 1 531 ? 46.501 75.262 -13.641 1.00 18.74 ? 531 TRP A CG 1 ATOM 4252 C CD1 . TRP A 1 531 ? 47.523 75.714 -12.812 1.00 20.52 ? 531 TRP A CD1 1 ATOM 4253 C CD2 . TRP A 1 531 ? 45.302 75.352 -12.879 1.00 21.89 ? 531 TRP A CD2 1 ATOM 4254 N NE1 . TRP A 1 531 ? 47.004 76.078 -11.608 1.00 24.72 ? 531 TRP A NE1 1 ATOM 4255 C CE2 . TRP A 1 531 ? 45.651 75.868 -11.615 1.00 20.07 ? 531 TRP A CE2 1 ATOM 4256 C CE3 . TRP A 1 531 ? 43.976 75.052 -13.139 1.00 22.44 ? 531 TRP A CE3 1 ATOM 4257 C CZ2 . TRP A 1 531 ? 44.698 76.087 -10.595 1.00 23.68 ? 531 TRP A CZ2 1 ATOM 4258 C CZ3 . TRP A 1 531 ? 43.009 75.269 -12.125 1.00 23.44 ? 531 TRP A CZ3 1 ATOM 4259 C CH2 . TRP A 1 531 ? 43.390 75.781 -10.875 1.00 24.36 ? 531 TRP A CH2 1 ATOM 4260 N N . PRO A 1 532 ? 46.637 78.328 -14.830 1.00 18.37 ? 532 PRO A N 1 ATOM 4261 C CA . PRO A 1 532 ? 45.249 78.526 -14.405 1.00 19.51 ? 532 PRO A CA 1 ATOM 4262 C C . PRO A 1 532 ? 44.358 78.785 -15.610 1.00 21.77 ? 532 PRO A C 1 ATOM 4263 O O . PRO A 1 532 ? 43.140 78.621 -15.554 1.00 22.74 ? 532 PRO A O 1 ATOM 4264 C CB . PRO A 1 532 ? 45.329 79.749 -13.483 1.00 20.56 ? 532 PRO A CB 1 ATOM 4265 C CG . PRO A 1 532 ? 46.709 79.638 -12.883 1.00 22.53 ? 532 PRO A CG 1 ATOM 4266 C CD . PRO A 1 532 ? 47.539 79.263 -14.115 1.00 18.17 ? 532 PRO A CD 1 ATOM 4267 N N . GLY A 1 533 ? 44.984 79.162 -16.717 1.00 21.73 ? 533 GLY A N 1 ATOM 4268 C CA . GLY A 1 533 ? 44.219 79.401 -17.923 1.00 22.74 ? 533 GLY A CA 1 ATOM 4269 C C . GLY A 1 533 ? 44.114 80.844 -18.331 1.00 27.24 ? 533 GLY A C 1 ATOM 4270 O O . GLY A 1 533 ? 44.218 81.766 -17.498 1.00 26.33 ? 533 GLY A O 1 ATOM 4271 N N . SER A 1 534 ? 43.925 81.021 -19.642 1.00 31.58 ? 534 SER A N 1 ATOM 4272 C CA . SER A 1 534 ? 43.773 82.343 -20.226 1.00 35.31 ? 534 SER A CA 1 ATOM 4273 C C . SER A 1 534 ? 42.478 82.854 -19.656 1.00 35.04 ? 534 SER A C 1 ATOM 4274 O O . SER A 1 534 ? 41.449 82.141 -19.663 1.00 35.97 ? 534 SER A O 1 ATOM 4275 C CB . SER A 1 534 ? 43.673 82.282 -21.762 1.00 38.84 ? 534 SER A CB 1 ATOM 4276 O OG . SER A 1 534 ? 43.544 83.591 -22.319 1.00 41.76 ? 534 SER A OG 1 ATOM 4277 N N . GLY A 1 535 ? 42.523 84.079 -19.159 1.00 33.61 ? 535 GLY A N 1 ATOM 4278 C CA . GLY A 1 535 ? 41.325 84.661 -18.591 1.00 31.83 ? 535 GLY A CA 1 ATOM 4279 C C . GLY A 1 535 ? 41.208 84.381 -17.111 1.00 31.45 ? 535 GLY A C 1 ATOM 4280 O O . GLY A 1 535 ? 40.346 84.945 -16.424 1.00 32.98 ? 535 GLY A O 1 ATOM 4281 N N . VAL A 1 536 ? 42.061 83.497 -16.596 1.00 30.81 ? 536 VAL A N 1 ATOM 4282 C CA . VAL A 1 536 ? 42.012 83.206 -15.168 1.00 29.83 ? 536 VAL A CA 1 ATOM 4283 C C . VAL A 1 536 ? 43.186 83.918 -14.498 1.00 32.44 ? 536 VAL A C 1 ATOM 4284 O O . VAL A 1 536 ? 43.018 84.624 -13.515 1.00 31.70 ? 536 VAL A O 1 ATOM 4285 C CB . VAL A 1 536 ? 42.051 81.667 -14.904 1.00 29.63 ? 536 VAL A CB 1 ATOM 4286 C CG1 . VAL A 1 536 ? 41.952 81.364 -13.393 1.00 29.94 ? 536 VAL A CG1 1 ATOM 4287 C CG2 . VAL A 1 536 ? 40.848 81.003 -15.630 1.00 29.38 ? 536 VAL A CG2 1 ATOM 4288 N N . GLU A 1 537 ? 44.376 83.755 -15.057 1.00 34.28 ? 537 GLU A N 1 ATOM 4289 C CA . GLU A 1 537 ? 45.564 84.407 -14.525 1.00 36.45 ? 537 GLU A CA 1 ATOM 4290 C C . GLU A 1 537 ? 46.477 84.653 -15.734 1.00 37.66 ? 537 GLU A C 1 ATOM 4291 O O . GLU A 1 537 ? 46.719 83.733 -16.525 1.00 37.57 ? 537 GLU A O 1 ATOM 4292 C CB . GLU A 1 537 ? 46.251 83.477 -13.518 1.00 39.01 ? 537 GLU A CB 1 ATOM 4293 C CG . GLU A 1 537 ? 47.440 84.067 -12.780 1.00 44.01 ? 537 GLU A CG 1 ATOM 4294 C CD . GLU A 1 537 ? 48.043 83.091 -11.768 1.00 47.70 ? 537 GLU A CD 1 ATOM 4295 O OE1 . GLU A 1 537 ? 47.481 82.970 -10.647 1.00 48.64 ? 537 GLU A OE1 1 ATOM 4296 O OE2 . GLU A 1 537 ? 49.067 82.434 -12.100 1.00 49.03 ? 537 GLU A OE2 1 ATOM 4297 N N . ASP A 1 538 ? 46.954 85.882 -15.920 1.00 40.26 ? 538 ASP A N 1 ATOM 4298 C CA . ASP A 1 538 ? 47.864 86.128 -17.051 1.00 43.10 ? 538 ASP A CA 1 ATOM 4299 C C . ASP A 1 538 ? 49.227 85.788 -16.432 1.00 42.32 ? 538 ASP A C 1 ATOM 4300 O O . ASP A 1 538 ? 49.921 86.661 -15.900 1.00 43.92 ? 538 ASP A O 1 ATOM 4301 C CB . ASP A 1 538 ? 47.810 87.602 -17.495 1.00 46.23 ? 538 ASP A CB 1 ATOM 4302 C CG . ASP A 1 538 ? 48.650 87.877 -18.761 1.00 50.86 ? 538 ASP A CG 1 ATOM 4303 O OD1 . ASP A 1 538 ? 49.804 87.382 -18.830 1.00 52.37 ? 538 ASP A OD1 1 ATOM 4304 O OD2 . ASP A 1 538 ? 48.168 88.597 -19.683 1.00 51.38 ? 538 ASP A OD2 1 ATOM 4305 N N . SER A 1 539 ? 49.606 84.516 -16.464 1.00 38.59 ? 539 SER A N 1 ATOM 4306 C CA . SER A 1 539 ? 50.870 84.133 -15.843 1.00 36.88 ? 539 SER A CA 1 ATOM 4307 C C . SER A 1 539 ? 51.884 83.457 -16.761 1.00 34.48 ? 539 SER A C 1 ATOM 4308 O O . SER A 1 539 ? 52.994 83.145 -16.322 1.00 34.48 ? 539 SER A O 1 ATOM 4309 C CB . SER A 1 539 ? 50.601 83.225 -14.642 1.00 37.90 ? 539 SER A CB 1 ATOM 4310 O OG . SER A 1 539 ? 50.171 81.935 -15.054 1.00 37.87 ? 539 SER A OG 1 ATOM 4311 N N . ARG A 1 540 ? 51.497 83.224 -18.011 1.00 31.02 ? 540 ARG A N 1 ATOM 4312 C CA . ARG A 1 540 ? 52.396 82.587 -18.959 1.00 28.60 ? 540 ARG A CA 1 ATOM 4313 C C . ARG A 1 540 ? 53.476 83.565 -19.354 1.00 28.21 ? 540 ARG A C 1 ATOM 4314 O O . ARG A 1 540 ? 53.201 84.738 -19.555 1.00 30.95 ? 540 ARG A O 1 ATOM 4315 C CB . ARG A 1 540 ? 51.641 82.155 -20.204 1.00 27.27 ? 540 ARG A CB 1 ATOM 4316 C CG . ARG A 1 540 ? 50.790 80.923 -19.941 1.00 25.31 ? 540 ARG A CG 1 ATOM 4317 C CD . ARG A 1 540 ? 50.074 80.478 -21.162 1.00 22.48 ? 540 ARG A CD 1 ATOM 4318 N NE . ARG A 1 540 ? 50.969 79.798 -22.091 1.00 20.49 ? 540 ARG A NE 1 ATOM 4319 C CZ . ARG A 1 540 ? 50.588 79.396 -23.295 1.00 20.18 ? 540 ARG A CZ 1 ATOM 4320 N NH1 . ARG A 1 540 ? 49.332 79.606 -23.719 1.00 21.37 ? 540 ARG A NH1 1 ATOM 4321 N NH2 . ARG A 1 540 ? 51.466 78.795 -24.078 1.00 19.30 ? 540 ARG A NH2 1 ATOM 4322 N N . THR A 1 541 ? 54.704 83.072 -19.472 1.00 25.77 ? 541 THR A N 1 ATOM 4323 C CA . THR A 1 541 ? 55.790 83.948 -19.859 1.00 25.71 ? 541 THR A CA 1 ATOM 4324 C C . THR A 1 541 ? 55.894 83.984 -21.386 1.00 22.48 ? 541 THR A C 1 ATOM 4325 O O . THR A 1 541 ? 55.693 82.986 -22.059 1.00 26.07 ? 541 THR A O 1 ATOM 4326 C CB . THR A 1 541 ? 57.117 83.448 -19.284 1.00 28.24 ? 541 THR A CB 1 ATOM 4327 O OG1 . THR A 1 541 ? 57.609 82.407 -20.113 1.00 31.55 ? 541 THR A OG1 1 ATOM 4328 C CG2 . THR A 1 541 ? 56.929 82.889 -17.896 1.00 27.52 ? 541 THR A CG2 1 ATOM 4329 N N . THR A 1 542 ? 56.181 85.158 -21.912 1.00 21.08 ? 542 THR A N 1 ATOM 4330 C CA . THR A 1 542 ? 56.376 85.298 -23.339 1.00 18.74 ? 542 THR A CA 1 ATOM 4331 C C . THR A 1 542 ? 57.850 85.035 -23.639 1.00 16.26 ? 542 THR A C 1 ATOM 4332 O O . THR A 1 542 ? 58.744 85.483 -22.893 1.00 18.84 ? 542 THR A O 1 ATOM 4333 C CB . THR A 1 542 ? 56.039 86.726 -23.770 1.00 20.82 ? 542 THR A CB 1 ATOM 4334 O OG1 . THR A 1 542 ? 54.682 86.985 -23.429 1.00 22.41 ? 542 THR A OG1 1 ATOM 4335 C CG2 . THR A 1 542 ? 56.223 86.924 -25.262 1.00 21.16 ? 542 THR A CG2 1 ATOM 4336 N N . ILE A 1 543 ? 58.104 84.296 -24.708 1.00 15.99 ? 543 ILE A N 1 ATOM 4337 C CA . ILE A 1 543 ? 59.480 84.056 -25.140 1.00 15.72 ? 543 ILE A CA 1 ATOM 4338 C C . ILE A 1 543 ? 59.837 85.353 -25.925 1.00 16.68 ? 543 ILE A C 1 ATOM 4339 O O . ILE A 1 543 ? 59.229 85.664 -26.975 1.00 16.66 ? 543 ILE A O 1 ATOM 4340 C CB . ILE A 1 543 ? 59.548 82.828 -26.017 1.00 16.09 ? 543 ILE A CB 1 ATOM 4341 C CG1 . ILE A 1 543 ? 59.217 81.565 -25.155 1.00 16.88 ? 543 ILE A CG1 1 ATOM 4342 C CG2 . ILE A 1 543 ? 60.927 82.765 -26.720 1.00 16.45 ? 543 ILE A CG2 1 ATOM 4343 C CD1 . ILE A 1 543 ? 59.132 80.297 -25.969 1.00 16.51 ? 543 ILE A CD1 1 ATOM 4344 N N . ILE A 1 544 ? 60.778 86.106 -25.367 1.00 16.29 ? 544 ILE A N 1 ATOM 4345 C CA . ILE A 1 544 ? 61.179 87.384 -25.937 1.00 17.43 ? 544 ILE A CA 1 ATOM 4346 C C . ILE A 1 544 ? 62.386 87.236 -26.862 1.00 18.49 ? 544 ILE A C 1 ATOM 4347 O O . ILE A 1 544 ? 63.494 86.891 -26.423 1.00 17.96 ? 544 ILE A O 1 ATOM 4348 C CB . ILE A 1 544 ? 61.421 88.370 -24.785 1.00 20.31 ? 544 ILE A CB 1 ATOM 4349 C CG1 . ILE A 1 544 ? 60.092 88.596 -24.043 1.00 25.01 ? 544 ILE A CG1 1 ATOM 4350 C CG2 . ILE A 1 544 ? 61.970 89.677 -25.309 1.00 23.41 ? 544 ILE A CG2 1 ATOM 4351 C CD1 . ILE A 1 544 ? 60.155 89.554 -22.841 1.00 28.64 ? 544 ILE A CD1 1 ATOM 4352 N N . LEU A 1 545 ? 62.124 87.432 -28.150 1.00 17.80 ? 545 LEU A N 1 ATOM 4353 C CA . LEU A 1 545 ? 63.163 87.302 -29.170 1.00 16.97 ? 545 LEU A CA 1 ATOM 4354 C C . LEU A 1 545 ? 63.298 88.660 -29.853 1.00 19.58 ? 545 LEU A C 1 ATOM 4355 O O . LEU A 1 545 ? 62.362 89.448 -29.877 1.00 20.84 ? 545 LEU A O 1 ATOM 4356 C CB . LEU A 1 545 ? 62.780 86.229 -30.200 1.00 18.17 ? 545 LEU A CB 1 ATOM 4357 C CG . LEU A 1 545 ? 62.548 84.818 -29.638 1.00 17.98 ? 545 LEU A CG 1 ATOM 4358 C CD1 . LEU A 1 545 ? 62.078 83.875 -30.716 1.00 20.73 ? 545 LEU A CD1 1 ATOM 4359 C CD2 . LEU A 1 545 ? 63.848 84.287 -29.061 1.00 17.94 ? 545 LEU A CD2 1 ATOM 4360 N N . GLY A 1 546 ? 64.456 88.921 -30.425 1.00 19.12 ? 546 GLY A N 1 ATOM 4361 C CA . GLY A 1 546 ? 64.661 90.205 -31.077 1.00 20.26 ? 546 GLY A CA 1 ATOM 4362 C C . GLY A 1 546 ? 66.067 90.253 -31.617 1.00 18.42 ? 546 GLY A C 1 ATOM 4363 O O . GLY A 1 546 ? 67.007 89.743 -31.009 1.00 18.42 ? 546 GLY A O 1 ATOM 4364 N N . GLU A 1 547 ? 66.227 90.900 -32.756 1.00 19.89 ? 547 GLU A N 1 ATOM 4365 C CA . GLU A 1 547 ? 67.555 91.005 -33.358 1.00 25.11 ? 547 GLU A CA 1 ATOM 4366 C C . GLU A 1 547 ? 68.599 91.650 -32.441 1.00 25.35 ? 547 GLU A C 1 ATOM 4367 O O . GLU A 1 547 ? 69.776 91.324 -32.498 1.00 27.95 ? 547 GLU A O 1 ATOM 4368 C CB . GLU A 1 547 ? 67.480 91.815 -34.645 1.00 29.60 ? 547 GLU A CB 1 ATOM 4369 C CG . GLU A 1 547 ? 68.804 91.780 -35.410 1.00 39.59 ? 547 GLU A CG 1 ATOM 4370 C CD . GLU A 1 547 ? 68.794 92.637 -36.667 1.00 44.41 ? 547 GLU A CD 1 ATOM 4371 O OE1 . GLU A 1 547 ? 67.743 92.681 -37.359 1.00 47.09 ? 547 GLU A OE1 1 ATOM 4372 O OE2 . GLU A 1 547 ? 69.849 93.254 -36.971 1.00 48.28 ? 547 GLU A OE2 1 ATOM 4373 N N . ASP A 1 548 ? 68.130 92.554 -31.590 1.00 23.34 ? 548 ASP A N 1 ATOM 4374 C CA . ASP A 1 548 ? 69.001 93.265 -30.666 1.00 23.89 ? 548 ASP A CA 1 ATOM 4375 C C . ASP A 1 548 ? 68.953 92.681 -29.264 1.00 25.82 ? 548 ASP A C 1 ATOM 4376 O O . ASP A 1 548 ? 69.314 93.355 -28.286 1.00 28.54 ? 548 ASP A O 1 ATOM 4377 C CB . ASP A 1 548 ? 68.596 94.746 -30.615 1.00 25.01 ? 548 ASP A CB 1 ATOM 4378 C CG . ASP A 1 548 ? 68.798 95.445 -31.942 1.00 27.13 ? 548 ASP A CG 1 ATOM 4379 O OD1 . ASP A 1 548 ? 69.953 95.504 -32.403 1.00 30.08 ? 548 ASP A OD1 1 ATOM 4380 O OD2 . ASP A 1 548 ? 67.816 95.938 -32.517 1.00 30.28 ? 548 ASP A OD2 1 ATOM 4381 N N . ILE A 1 549 ? 68.500 91.440 -29.120 1.00 21.96 ? 549 ILE A N 1 ATOM 4382 C CA . ILE A 1 549 ? 68.501 90.891 -27.774 1.00 22.07 ? 549 ILE A CA 1 ATOM 4383 C C . ILE A 1 549 ? 68.716 89.378 -27.732 1.00 21.92 ? 549 ILE A C 1 ATOM 4384 O O . ILE A 1 549 ? 69.538 88.908 -26.975 1.00 21.83 ? 549 ILE A O 1 ATOM 4385 C CB . ILE A 1 549 ? 67.187 91.257 -26.965 1.00 21.83 ? 549 ILE A CB 1 ATOM 4386 C CG1 . ILE A 1 549 ? 67.303 90.684 -25.527 1.00 25.89 ? 549 ILE A CG1 1 ATOM 4387 C CG2 . ILE A 1 549 ? 65.922 90.762 -27.689 1.00 21.88 ? 549 ILE A CG2 1 ATOM 4388 C CD1 . ILE A 1 549 ? 66.094 90.948 -24.603 1.00 27.83 ? 549 ILE A CD1 1 ATOM 4389 N N . LEU A 1 550 ? 67.999 88.633 -28.559 1.00 19.29 ? 550 LEU A N 1 ATOM 4390 C CA . LEU A 1 550 ? 68.096 87.174 -28.497 1.00 19.34 ? 550 LEU A CA 1 ATOM 4391 C C . LEU A 1 550 ? 67.465 86.604 -29.745 1.00 18.00 ? 550 LEU A C 1 ATOM 4392 O O . LEU A 1 550 ? 66.263 86.728 -29.979 1.00 19.31 ? 550 LEU A O 1 ATOM 4393 C CB . LEU A 1 550 ? 67.336 86.657 -27.267 1.00 20.65 ? 550 LEU A CB 1 ATOM 4394 C CG . LEU A 1 550 ? 67.415 85.132 -27.041 1.00 20.25 ? 550 LEU A CG 1 ATOM 4395 C CD1 . LEU A 1 550 ? 68.843 84.705 -26.851 1.00 21.23 ? 550 LEU A CD1 1 ATOM 4396 C CD2 . LEU A 1 550 ? 66.588 84.757 -25.818 1.00 21.07 ? 550 LEU A CD2 1 ATOM 4397 N N . PRO A 1 551 ? 68.261 85.941 -30.567 1.00 19.39 ? 551 PRO A N 1 ATOM 4398 C CA . PRO A 1 551 ? 67.696 85.387 -31.793 1.00 18.51 ? 551 PRO A CA 1 ATOM 4399 C C . PRO A 1 551 ? 66.809 84.154 -31.658 1.00 18.56 ? 551 PRO A C 1 ATOM 4400 O O . PRO A 1 551 ? 65.895 83.950 -32.475 1.00 19.64 ? 551 PRO A O 1 ATOM 4401 C CB . PRO A 1 551 ? 68.932 85.028 -32.641 1.00 19.02 ? 551 PRO A CB 1 ATOM 4402 C CG . PRO A 1 551 ? 70.043 85.796 -32.041 1.00 24.48 ? 551 PRO A CG 1 ATOM 4403 C CD . PRO A 1 551 ? 69.733 85.877 -30.554 1.00 20.74 ? 551 PRO A CD 1 ATOM 4404 N N . SER A 1 552 ? 67.101 83.328 -30.656 1.00 17.40 ? 552 SER A N 1 ATOM 4405 C CA . SER A 1 552 ? 66.381 82.066 -30.577 1.00 16.76 ? 552 SER A CA 1 ATOM 4406 C C . SER A 1 552 ? 66.268 81.563 -29.168 1.00 16.86 ? 552 SER A C 1 ATOM 4407 O O . SER A 1 552 ? 66.937 82.026 -28.281 1.00 16.54 ? 552 SER A O 1 ATOM 4408 C CB . SER A 1 552 ? 67.096 81.012 -31.406 1.00 18.76 ? 552 SER A CB 1 ATOM 4409 O OG . SER A 1 552 ? 68.371 80.706 -30.894 1.00 21.58 ? 552 SER A OG 1 ATOM 4410 N N . LYS A 1 553 ? 65.437 80.544 -29.004 1.00 15.53 ? 553 LYS A N 1 ATOM 4411 C CA . LYS A 1 553 ? 65.169 79.990 -27.675 1.00 14.83 ? 553 LYS A CA 1 ATOM 4412 C C . LYS A 1 553 ? 64.857 78.505 -27.793 1.00 14.60 ? 553 LYS A C 1 ATOM 4413 O O . LYS A 1 553 ? 64.064 78.060 -28.642 1.00 14.69 ? 553 LYS A O 1 ATOM 4414 C CB . LYS A 1 553 ? 63.915 80.698 -27.113 1.00 16.51 ? 553 LYS A CB 1 ATOM 4415 C CG . LYS A 1 553 ? 63.366 80.050 -25.802 1.00 18.10 ? 553 LYS A CG 1 ATOM 4416 C CD . LYS A 1 553 ? 64.378 80.178 -24.682 1.00 17.43 ? 553 LYS A CD 1 ATOM 4417 C CE . LYS A 1 553 ? 64.687 81.642 -24.325 1.00 18.01 ? 553 LYS A CE 1 ATOM 4418 N NZ . LYS A 1 553 ? 65.856 81.764 -23.355 1.00 19.10 ? 553 LYS A NZ 1 ATOM 4419 N N . HIS A 1 554 ? 65.487 77.746 -26.904 1.00 14.71 ? 554 HIS A N 1 ATOM 4420 C CA . HIS A 1 554 ? 65.215 76.312 -26.804 1.00 14.39 ? 554 HIS A CA 1 ATOM 4421 C C . HIS A 1 554 ? 64.018 76.040 -25.880 1.00 14.57 ? 554 HIS A C 1 ATOM 4422 O O . HIS A 1 554 ? 63.866 76.673 -24.827 1.00 14.92 ? 554 HIS A O 1 ATOM 4423 C CB . HIS A 1 554 ? 66.421 75.574 -26.190 1.00 17.26 ? 554 HIS A CB 1 ATOM 4424 C CG . HIS A 1 554 ? 67.570 75.451 -27.126 1.00 19.34 ? 554 HIS A CG 1 ATOM 4425 N ND1 . HIS A 1 554 ? 68.219 74.265 -27.389 1.00 25.88 ? 554 HIS A ND1 1 ATOM 4426 C CD2 . HIS A 1 554 ? 68.205 76.400 -27.864 1.00 23.73 ? 554 HIS A CD2 1 ATOM 4427 C CE1 . HIS A 1 554 ? 69.213 74.491 -28.232 1.00 21.25 ? 554 HIS A CE1 1 ATOM 4428 N NE2 . HIS A 1 554 ? 69.225 75.775 -28.534 1.00 27.91 ? 554 HIS A NE2 1 ATOM 4429 N N . VAL A 1 555 ? 63.180 75.123 -26.330 1.00 12.55 ? 555 VAL A N 1 ATOM 4430 C CA . VAL A 1 555 ? 62.038 74.636 -25.542 1.00 13.41 ? 555 VAL A CA 1 ATOM 4431 C C . VAL A 1 555 ? 62.126 73.125 -25.534 1.00 13.35 ? 555 VAL A C 1 ATOM 4432 O O . VAL A 1 555 ? 62.655 72.513 -26.469 1.00 14.33 ? 555 VAL A O 1 ATOM 4433 C CB . VAL A 1 555 ? 60.652 75.096 -26.099 1.00 13.29 ? 555 VAL A CB 1 ATOM 4434 C CG1 . VAL A 1 555 ? 60.574 76.617 -26.015 1.00 14.29 ? 555 VAL A CG1 1 ATOM 4435 C CG2 . VAL A 1 555 ? 60.433 74.605 -27.515 1.00 14.18 ? 555 VAL A CG2 1 ATOM 4436 N N . VAL A 1 556 ? 61.595 72.498 -24.471 1.00 12.77 ? 556 VAL A N 1 ATOM 4437 C CA . VAL A 1 556 ? 61.655 71.044 -24.324 1.00 13.16 ? 556 VAL A CA 1 ATOM 4438 C C . VAL A 1 556 ? 60.288 70.538 -23.906 1.00 11.48 ? 556 VAL A C 1 ATOM 4439 O O . VAL A 1 556 ? 59.636 71.153 -23.030 1.00 13.28 ? 556 VAL A O 1 ATOM 4440 C CB . VAL A 1 556 ? 62.660 70.640 -23.210 1.00 12.64 ? 556 VAL A CB 1 ATOM 4441 C CG1 . VAL A 1 556 ? 62.586 69.154 -22.950 1.00 12.31 ? 556 VAL A CG1 1 ATOM 4442 C CG2 . VAL A 1 556 ? 64.054 71.048 -23.632 1.00 13.48 ? 556 VAL A CG2 1 ATOM 4443 N N . MET A 1 557 ? 59.855 69.459 -24.522 1.00 12.58 ? 557 MET A N 1 ATOM 4444 C CA . MET A 1 557 ? 58.593 68.810 -24.154 1.00 12.13 ? 557 MET A CA 1 ATOM 4445 C C . MET A 1 557 ? 58.892 67.489 -23.491 1.00 13.63 ? 557 MET A C 1 ATOM 4446 O O . MET A 1 557 ? 59.778 66.757 -23.907 1.00 13.02 ? 557 MET A O 1 ATOM 4447 C CB . MET A 1 557 ? 57.698 68.511 -25.389 1.00 12.86 ? 557 MET A CB 1 ATOM 4448 C CG . MET A 1 557 ? 56.699 69.641 -25.702 1.00 14.11 ? 557 MET A CG 1 ATOM 4449 S SD . MET A 1 557 ? 57.381 71.273 -25.930 1.00 15.04 ? 557 MET A SD 1 ATOM 4450 C CE . MET A 1 557 ? 58.406 70.980 -27.395 1.00 15.87 ? 557 MET A CE 1 ATOM 4451 N N . HIS A 1 558 ? 58.127 67.187 -22.438 1.00 11.26 ? 558 HIS A N 1 ATOM 4452 C CA . HIS A 1 558 ? 58.206 65.880 -21.775 1.00 11.61 ? 558 HIS A CA 1 ATOM 4453 C C . HIS A 1 558 ? 56.893 65.107 -21.985 1.00 11.75 ? 558 HIS A C 1 ATOM 4454 O O . HIS A 1 558 ? 55.798 65.681 -21.973 1.00 12.13 ? 558 HIS A O 1 ATOM 4455 C CB . HIS A 1 558 ? 58.385 66.064 -20.256 1.00 11.31 ? 558 HIS A CB 1 ATOM 4456 C CG . HIS A 1 558 ? 58.252 64.798 -19.477 1.00 10.62 ? 558 HIS A CG 1 ATOM 4457 N ND1 . HIS A 1 558 ? 57.292 64.643 -18.486 1.00 12.40 ? 558 HIS A ND1 1 ATOM 4458 C CD2 . HIS A 1 558 ? 58.981 63.659 -19.486 1.00 10.55 ? 558 HIS A CD2 1 ATOM 4459 C CE1 . HIS A 1 558 ? 57.453 63.456 -17.917 1.00 12.43 ? 558 HIS A CE1 1 ATOM 4460 N NE2 . HIS A 1 558 ? 58.464 62.833 -18.506 1.00 12.31 ? 558 HIS A NE2 1 ATOM 4461 N N . ASN A 1 559 ? 57.018 63.797 -22.208 1.00 10.85 ? 559 ASN A N 1 ATOM 4462 C CA . ASN A 1 559 ? 55.871 62.943 -22.395 1.00 10.64 ? 559 ASN A CA 1 ATOM 4463 C C . ASN A 1 559 ? 55.876 61.870 -21.320 1.00 12.38 ? 559 ASN A C 1 ATOM 4464 O O . ASN A 1 559 ? 56.587 60.914 -21.439 1.00 12.80 ? 559 ASN A O 1 ATOM 4465 C CB . ASN A 1 559 ? 55.945 62.287 -23.796 1.00 12.47 ? 559 ASN A CB 1 ATOM 4466 C CG . ASN A 1 559 ? 54.948 61.202 -23.985 1.00 12.23 ? 559 ASN A CG 1 ATOM 4467 O OD1 . ASN A 1 559 ? 53.859 61.179 -23.396 1.00 13.13 ? 559 ASN A OD1 1 ATOM 4468 N ND2 . ASN A 1 559 ? 55.288 60.274 -24.871 1.00 13.50 ? 559 ASN A ND2 1 ATOM 4469 N N . THR A 1 560 ? 55.009 62.004 -20.321 1.00 10.87 ? 560 THR A N 1 ATOM 4470 C CA . THR A 1 560 ? 55.029 61.006 -19.222 1.00 11.53 ? 560 THR A CA 1 ATOM 4471 C C . THR A 1 560 ? 54.411 59.652 -19.618 1.00 12.43 ? 560 THR A C 1 ATOM 4472 O O . THR A 1 560 ? 54.588 58.677 -18.892 1.00 13.28 ? 560 THR A O 1 ATOM 4473 C CB . THR A 1 560 ? 54.259 61.615 -18.041 1.00 12.46 ? 560 THR A CB 1 ATOM 4474 O OG1 . THR A 1 560 ? 54.554 60.880 -16.841 1.00 12.56 ? 560 THR A OG1 1 ATOM 4475 C CG2 . THR A 1 560 ? 52.787 61.611 -18.280 1.00 12.77 ? 560 THR A CG2 1 ATOM 4476 N N . LEU A 1 561 ? 53.677 59.574 -20.740 1.00 12.26 ? 561 LEU A N 1 ATOM 4477 C CA . LEU A 1 561 ? 53.066 58.330 -21.156 1.00 12.75 ? 561 LEU A CA 1 ATOM 4478 C C . LEU A 1 561 ? 54.072 57.410 -21.838 1.00 12.60 ? 561 LEU A C 1 ATOM 4479 O O . LEU A 1 561 ? 54.955 57.869 -22.562 1.00 12.06 ? 561 LEU A O 1 ATOM 4480 C CB . LEU A 1 561 ? 51.921 58.621 -22.165 1.00 13.37 ? 561 LEU A CB 1 ATOM 4481 C CG . LEU A 1 561 ? 50.798 59.543 -21.609 1.00 13.16 ? 561 LEU A CG 1 ATOM 4482 C CD1 . LEU A 1 561 ? 49.675 59.676 -22.677 1.00 15.47 ? 561 LEU A CD1 1 ATOM 4483 C CD2 . LEU A 1 561 ? 50.156 58.913 -20.388 1.00 13.77 ? 561 LEU A CD2 1 ATOM 4484 N N . PRO A 1 562 ? 53.896 56.100 -21.675 1.00 12.74 ? 562 PRO A N 1 ATOM 4485 C CA . PRO A 1 562 ? 54.807 55.124 -22.267 1.00 13.33 ? 562 PRO A CA 1 ATOM 4486 C C . PRO A 1 562 ? 54.633 54.772 -23.716 1.00 15.01 ? 562 PRO A C 1 ATOM 4487 O O . PRO A 1 562 ? 54.767 53.612 -24.095 1.00 14.95 ? 562 PRO A O 1 ATOM 4488 C CB . PRO A 1 562 ? 54.654 53.933 -21.326 1.00 13.57 ? 562 PRO A CB 1 ATOM 4489 C CG . PRO A 1 562 ? 53.189 53.960 -20.998 1.00 13.45 ? 562 PRO A CG 1 ATOM 4490 C CD . PRO A 1 562 ? 52.889 55.448 -20.813 1.00 12.89 ? 562 PRO A CD 1 ATOM 4491 N N . HIS A 1 563 ? 54.311 55.775 -24.527 1.00 14.50 ? 563 HIS A N 1 ATOM 4492 C CA . HIS A 1 563 ? 54.236 55.543 -25.970 1.00 15.24 ? 563 HIS A CA 1 ATOM 4493 C C . HIS A 1 563 ? 54.605 56.829 -26.634 1.00 15.42 ? 563 HIS A C 1 ATOM 4494 O O . HIS A 1 563 ? 54.467 57.915 -26.060 1.00 15.91 ? 563 HIS A O 1 ATOM 4495 C CB . HIS A 1 563 ? 52.841 55.068 -26.439 1.00 14.91 ? 563 HIS A CB 1 ATOM 4496 C CG . HIS A 1 563 ? 51.703 55.930 -25.971 1.00 15.98 ? 563 HIS A CG 1 ATOM 4497 N ND1 . HIS A 1 563 ? 50.907 55.570 -24.907 1.00 15.20 ? 563 HIS A ND1 1 ATOM 4498 C CD2 . HIS A 1 563 ? 51.158 57.064 -26.483 1.00 15.27 ? 563 HIS A CD2 1 ATOM 4499 C CE1 . HIS A 1 563 ? 49.911 56.439 -24.786 1.00 16.68 ? 563 HIS A CE1 1 ATOM 4500 N NE2 . HIS A 1 563 ? 50.042 57.361 -25.727 1.00 16.50 ? 563 HIS A NE2 1 ATOM 4501 N N . TRP A 1 564 ? 55.153 56.721 -27.847 1.00 15.25 ? 564 TRP A N 1 ATOM 4502 C CA . TRP A 1 564 ? 55.471 57.918 -28.614 1.00 14.34 ? 564 TRP A CA 1 ATOM 4503 C C . TRP A 1 564 ? 54.212 58.759 -28.755 1.00 14.96 ? 564 TRP A C 1 ATOM 4504 O O . TRP A 1 564 ? 53.092 58.252 -28.968 1.00 15.84 ? 564 TRP A O 1 ATOM 4505 C CB . TRP A 1 564 ? 55.924 57.533 -30.038 1.00 16.47 ? 564 TRP A CB 1 ATOM 4506 C CG . TRP A 1 564 ? 57.320 57.088 -30.129 1.00 16.11 ? 564 TRP A CG 1 ATOM 4507 C CD1 . TRP A 1 564 ? 57.799 55.799 -29.998 1.00 16.79 ? 564 TRP A CD1 1 ATOM 4508 C CD2 . TRP A 1 564 ? 58.467 57.928 -30.279 1.00 15.74 ? 564 TRP A CD2 1 ATOM 4509 N NE1 . TRP A 1 564 ? 59.165 55.805 -30.048 1.00 17.76 ? 564 TRP A NE1 1 ATOM 4510 C CE2 . TRP A 1 564 ? 59.613 57.091 -30.223 1.00 16.95 ? 564 TRP A CE2 1 ATOM 4511 C CE3 . TRP A 1 564 ? 58.640 59.317 -30.453 1.00 15.60 ? 564 TRP A CE3 1 ATOM 4512 C CZ2 . TRP A 1 564 ? 60.930 57.598 -30.332 1.00 15.90 ? 564 TRP A CZ2 1 ATOM 4513 C CZ3 . TRP A 1 564 ? 59.955 59.830 -30.560 1.00 16.05 ? 564 TRP A CZ3 1 ATOM 4514 C CH2 . TRP A 1 564 ? 61.080 58.965 -30.498 1.00 17.71 ? 564 TRP A CH2 1 ATOM 4515 N N . ARG A 1 565 ? 54.382 60.061 -28.615 1.00 14.60 ? 565 ARG A N 1 ATOM 4516 C CA . ARG A 1 565 ? 53.238 60.909 -28.768 1.00 16.29 ? 565 ARG A CA 1 ATOM 4517 C C . ARG A 1 565 ? 53.571 62.137 -29.593 1.00 16.49 ? 565 ARG A C 1 ATOM 4518 O O . ARG A 1 565 ? 54.651 62.718 -29.461 1.00 18.84 ? 565 ARG A O 1 ATOM 4519 C CB . ARG A 1 565 ? 52.748 61.347 -27.374 1.00 19.88 ? 565 ARG A CB 1 ATOM 4520 C CG . ARG A 1 565 ? 51.391 61.974 -27.348 1.00 25.06 ? 565 ARG A CG 1 ATOM 4521 C CD . ARG A 1 565 ? 50.585 61.630 -26.033 1.00 22.52 ? 565 ARG A CD 1 ATOM 4522 N NE . ARG A 1 565 ? 51.339 61.981 -24.835 1.00 22.11 ? 565 ARG A NE 1 ATOM 4523 C CZ . ARG A 1 565 ? 50.817 62.626 -23.798 1.00 16.01 ? 565 ARG A CZ 1 ATOM 4524 N NH1 . ARG A 1 565 ? 49.528 63.012 -23.789 1.00 16.32 ? 565 ARG A NH1 1 ATOM 4525 N NH2 . ARG A 1 565 ? 51.620 62.913 -22.763 1.00 15.87 ? 565 ARG A NH2 1 ATOM 4526 N N . GLU A 1 566 ? 52.660 62.482 -30.481 1.00 19.25 ? 566 GLU A N 1 ATOM 4527 C CA . GLU A 1 566 ? 52.765 63.742 -31.194 1.00 21.51 ? 566 GLU A CA 1 ATOM 4528 C C . GLU A 1 566 ? 51.582 64.515 -30.603 1.00 24.60 ? 566 GLU A C 1 ATOM 4529 O O . GLU A 1 566 ? 50.542 63.920 -30.261 1.00 27.28 ? 566 GLU A O 1 ATOM 4530 C CB . GLU A 1 566 ? 52.532 63.589 -32.666 1.00 27.25 ? 566 GLU A CB 1 ATOM 4531 C CG . GLU A 1 566 ? 53.620 62.936 -33.345 1.00 25.56 ? 566 GLU A CG 1 ATOM 4532 C CD . GLU A 1 566 ? 53.349 62.901 -34.826 1.00 33.10 ? 566 GLU A CD 1 ATOM 4533 O OE1 . GLU A 1 566 ? 52.195 62.557 -35.202 1.00 36.50 ? 566 GLU A OE1 1 ATOM 4534 O OE2 . GLU A 1 566 ? 54.284 63.225 -35.590 1.00 32.54 ? 566 GLU A OE2 1 ATOM 4535 N N . GLN A 1 567 ? 51.716 65.825 -30.479 1.00 20.18 ? 567 GLN A N 1 ATOM 4536 C CA . GLN A 1 567 ? 50.633 66.644 -29.914 1.00 20.67 ? 567 GLN A CA 1 ATOM 4537 C C . GLN A 1 567 ? 51.020 68.084 -30.264 1.00 18.86 ? 567 GLN A C 1 ATOM 4538 O O . GLN A 1 567 ? 52.210 68.441 -30.265 1.00 17.31 ? 567 GLN A O 1 ATOM 4539 C CB . GLN A 1 567 ? 50.546 66.494 -28.356 1.00 22.42 ? 567 GLN A CB 1 ATOM 4540 C CG . GLN A 1 567 ? 49.424 67.359 -27.601 1.00 23.07 ? 567 GLN A CG 1 ATOM 4541 C CD . GLN A 1 567 ? 49.823 67.843 -26.144 1.00 25.17 ? 567 GLN A CD 1 ATOM 4542 O OE1 . GLN A 1 567 ? 49.815 67.050 -25.168 1.00 18.98 ? 567 GLN A OE1 1 ATOM 4543 N NE2 . GLN A 1 567 ? 50.186 69.146 -26.018 1.00 24.41 ? 567 GLN A NE2 1 ATOM 4544 N N . LEU A 1 568 ? 50.032 68.898 -30.616 1.00 16.20 ? 568 LEU A N 1 ATOM 4545 C CA . LEU A 1 568 ? 50.337 70.306 -30.860 1.00 15.90 ? 568 LEU A CA 1 ATOM 4546 C C . LEU A 1 568 ? 50.640 70.938 -29.516 1.00 14.77 ? 568 LEU A C 1 ATOM 4547 O O . LEU A 1 568 ? 49.965 70.655 -28.486 1.00 17.05 ? 568 LEU A O 1 ATOM 4548 C CB . LEU A 1 568 ? 49.140 71.055 -31.456 1.00 18.44 ? 568 LEU A CB 1 ATOM 4549 C CG . LEU A 1 568 ? 48.798 70.747 -32.913 1.00 20.48 ? 568 LEU A CG 1 ATOM 4550 C CD1 . LEU A 1 568 ? 47.751 71.766 -33.392 1.00 21.59 ? 568 LEU A CD1 1 ATOM 4551 C CD2 . LEU A 1 568 ? 50.031 70.872 -33.778 1.00 23.25 ? 568 LEU A CD2 1 ATOM 4552 N N . VAL A 1 569 ? 51.649 71.778 -29.540 1.00 13.05 ? 569 VAL A N 1 ATOM 4553 C CA . VAL A 1 569 ? 52.034 72.570 -28.371 1.00 12.80 ? 569 VAL A CA 1 ATOM 4554 C C . VAL A 1 569 ? 52.084 74.029 -28.765 1.00 14.82 ? 569 VAL A C 1 ATOM 4555 O O . VAL A 1 569 ? 52.319 74.380 -29.927 1.00 16.25 ? 569 VAL A O 1 ATOM 4556 C CB . VAL A 1 569 ? 53.410 72.192 -27.759 1.00 13.68 ? 569 VAL A CB 1 ATOM 4557 C CG1 . VAL A 1 569 ? 53.318 70.779 -27.127 1.00 14.63 ? 569 VAL A CG1 1 ATOM 4558 C CG2 . VAL A 1 569 ? 54.538 72.239 -28.814 1.00 14.47 ? 569 VAL A CG2 1 ATOM 4559 N N . ASP A 1 570 ? 51.852 74.906 -27.823 1.00 14.12 ? 570 ASP A N 1 ATOM 4560 C CA . ASP A 1 570 ? 51.898 76.320 -28.136 1.00 16.89 ? 570 ASP A CA 1 ATOM 4561 C C . ASP A 1 570 ? 52.668 77.108 -27.101 1.00 16.47 ? 570 ASP A C 1 ATOM 4562 O O . ASP A 1 570 ? 52.741 76.726 -25.919 1.00 17.82 ? 570 ASP A O 1 ATOM 4563 C CB . ASP A 1 570 ? 50.488 76.915 -28.303 1.00 19.24 ? 570 ASP A CB 1 ATOM 4564 C CG . ASP A 1 570 ? 49.687 76.976 -26.992 1.00 26.03 ? 570 ASP A CG 1 ATOM 4565 O OD1 . ASP A 1 570 ? 49.368 75.919 -26.428 1.00 30.72 ? 570 ASP A OD1 1 ATOM 4566 O OD2 . ASP A 1 570 ? 49.376 78.082 -26.523 1.00 28.33 ? 570 ASP A OD2 1 ATOM 4567 N N . PHE A 1 571 ? 53.271 78.198 -27.556 1.00 14.94 ? 571 PHE A N 1 ATOM 4568 C CA . PHE A 1 571 ? 54.017 79.111 -26.714 1.00 15.14 ? 571 PHE A CA 1 ATOM 4569 C C . PHE A 1 571 ? 53.685 80.540 -27.101 1.00 14.90 ? 571 PHE A C 1 ATOM 4570 O O . PHE A 1 571 ? 53.289 80.796 -28.256 1.00 16.46 ? 571 PHE A O 1 ATOM 4571 C CB . PHE A 1 571 ? 55.537 78.921 -26.933 1.00 15.27 ? 571 PHE A CB 1 ATOM 4572 C CG . PHE A 1 571 ? 56.040 77.575 -26.526 1.00 13.73 ? 571 PHE A CG 1 ATOM 4573 C CD1 . PHE A 1 571 ? 55.999 76.510 -27.390 1.00 14.73 ? 571 PHE A CD1 1 ATOM 4574 C CD2 . PHE A 1 571 ? 56.553 77.402 -25.240 1.00 15.32 ? 571 PHE A CD2 1 ATOM 4575 C CE1 . PHE A 1 571 ? 56.457 75.259 -26.991 1.00 15.40 ? 571 PHE A CE1 1 ATOM 4576 C CE2 . PHE A 1 571 ? 57.008 76.142 -24.840 1.00 13.16 ? 571 PHE A CE2 1 ATOM 4577 C CZ . PHE A 1 571 ? 56.955 75.083 -25.707 1.00 16.09 ? 571 PHE A CZ 1 ATOM 4578 N N . TYR A 1 572 ? 53.836 81.451 -26.148 1.00 14.87 ? 572 TYR A N 1 ATOM 4579 C CA . TYR A 1 572 ? 53.693 82.882 -26.441 1.00 15.39 ? 572 TYR A CA 1 ATOM 4580 C C . TYR A 1 572 ? 55.074 83.377 -26.875 1.00 17.38 ? 572 TYR A C 1 ATOM 4581 O O . TYR A 1 572 ? 56.101 83.045 -26.246 1.00 16.06 ? 572 TYR A O 1 ATOM 4582 C CB . TYR A 1 572 ? 53.257 83.674 -25.209 1.00 16.32 ? 572 TYR A CB 1 ATOM 4583 C CG . TYR A 1 572 ? 51.807 83.569 -24.827 1.00 20.07 ? 572 TYR A CG 1 ATOM 4584 C CD1 . TYR A 1 572 ? 50.907 82.843 -25.593 1.00 19.93 ? 572 TYR A CD1 1 ATOM 4585 C CD2 . TYR A 1 572 ? 51.340 84.196 -23.671 1.00 23.16 ? 572 TYR A CD2 1 ATOM 4586 C CE1 . TYR A 1 572 ? 49.561 82.725 -25.231 1.00 23.17 ? 572 TYR A CE1 1 ATOM 4587 C CE2 . TYR A 1 572 ? 49.992 84.088 -23.301 1.00 24.94 ? 572 TYR A CE2 1 ATOM 4588 C CZ . TYR A 1 572 ? 49.118 83.352 -24.092 1.00 22.47 ? 572 TYR A CZ 1 ATOM 4589 O OH . TYR A 1 572 ? 47.778 83.236 -23.742 1.00 28.78 ? 572 TYR A OH 1 ATOM 4590 N N . VAL A 1 573 ? 55.103 84.183 -27.941 1.00 15.47 ? 573 VAL A N 1 ATOM 4591 C CA . VAL A 1 573 ? 56.370 84.736 -28.457 1.00 16.24 ? 573 VAL A CA 1 ATOM 4592 C C . VAL A 1 573 ? 56.140 86.203 -28.737 1.00 15.47 ? 573 VAL A C 1 ATOM 4593 O O . VAL A 1 573 ? 55.011 86.621 -28.990 1.00 17.53 ? 573 VAL A O 1 ATOM 4594 C CB . VAL A 1 573 ? 56.830 84.053 -29.756 1.00 16.06 ? 573 VAL A CB 1 ATOM 4595 C CG1 . VAL A 1 573 ? 57.399 82.684 -29.427 1.00 17.64 ? 573 VAL A CG1 1 ATOM 4596 C CG2 . VAL A 1 573 ? 55.682 83.929 -30.740 1.00 17.13 ? 573 VAL A CG2 1 ATOM 4597 N N . SER A 1 574 ? 57.219 86.980 -28.743 1.00 17.33 ? 574 SER A N 1 ATOM 4598 C CA . SER A 1 574 ? 57.104 88.438 -28.906 1.00 18.85 ? 574 SER A CA 1 ATOM 4599 C C . SER A 1 574 ? 57.063 88.955 -30.332 1.00 20.58 ? 574 SER A C 1 ATOM 4600 O O . SER A 1 574 ? 57.009 90.188 -30.557 1.00 24.14 ? 574 SER A O 1 ATOM 4601 C CB . SER A 1 574 ? 58.230 89.119 -28.128 1.00 20.26 ? 574 SER A CB 1 ATOM 4602 O OG . SER A 1 574 ? 59.502 88.788 -28.650 1.00 18.84 ? 574 SER A OG 1 ATOM 4603 N N . SER A 1 575 ? 57.058 88.038 -31.286 1.00 20.89 ? 575 SER A N 1 ATOM 4604 C CA . SER A 1 575 ? 56.989 88.389 -32.691 1.00 20.37 ? 575 SER A CA 1 ATOM 4605 C C . SER A 1 575 ? 56.242 87.304 -33.437 1.00 20.80 ? 575 SER A C 1 ATOM 4606 O O . SER A 1 575 ? 56.292 86.124 -33.065 1.00 17.78 ? 575 SER A O 1 ATOM 4607 C CB . SER A 1 575 ? 58.407 88.471 -33.278 1.00 21.35 ? 575 SER A CB 1 ATOM 4608 O OG . SER A 1 575 ? 58.407 88.566 -34.709 1.00 22.24 ? 575 SER A OG 1 ATOM 4609 N N . PRO A 1 576 ? 55.535 87.673 -34.507 1.00 19.17 ? 576 PRO A N 1 ATOM 4610 C CA . PRO A 1 576 ? 54.818 86.661 -35.281 1.00 19.31 ? 576 PRO A CA 1 ATOM 4611 C C . PRO A 1 576 ? 55.768 85.982 -36.272 1.00 18.75 ? 576 PRO A C 1 ATOM 4612 O O . PRO A 1 576 ? 55.419 84.982 -36.883 1.00 20.92 ? 576 PRO A O 1 ATOM 4613 C CB . PRO A 1 576 ? 53.725 87.457 -35.984 1.00 20.27 ? 576 PRO A CB 1 ATOM 4614 C CG . PRO A 1 576 ? 54.331 88.830 -36.133 1.00 23.86 ? 576 PRO A CG 1 ATOM 4615 C CD . PRO A 1 576 ? 55.216 89.051 -34.928 1.00 19.83 ? 576 PRO A CD 1 ATOM 4616 N N . PHE A 1 577 ? 56.990 86.516 -36.419 1.00 18.75 ? 577 PHE A N 1 ATOM 4617 C CA . PHE A 1 577 ? 57.896 85.962 -37.427 1.00 19.73 ? 577 PHE A CA 1 ATOM 4618 C C . PHE A 1 577 ? 58.842 85.001 -36.762 1.00 20.17 ? 577 PHE A C 1 ATOM 4619 O O . PHE A 1 577 ? 60.010 85.298 -36.550 1.00 20.03 ? 577 PHE A O 1 ATOM 4620 C CB . PHE A 1 577 ? 58.656 87.099 -38.122 1.00 19.65 ? 577 PHE A CB 1 ATOM 4621 C CG . PHE A 1 577 ? 57.738 88.147 -38.715 1.00 24.98 ? 577 PHE A CG 1 ATOM 4622 C CD1 . PHE A 1 577 ? 56.681 87.770 -39.523 1.00 21.79 ? 577 PHE A CD1 1 ATOM 4623 C CD2 . PHE A 1 577 ? 57.978 89.509 -38.496 1.00 26.96 ? 577 PHE A CD2 1 ATOM 4624 C CE1 . PHE A 1 577 ? 55.855 88.743 -40.129 1.00 26.24 ? 577 PHE A CE1 1 ATOM 4625 C CE2 . PHE A 1 577 ? 57.171 90.481 -39.091 1.00 29.09 ? 577 PHE A CE2 1 ATOM 4626 C CZ . PHE A 1 577 ? 56.115 90.084 -39.905 1.00 28.50 ? 577 PHE A CZ 1 ATOM 4627 N N . VAL A 1 578 ? 58.292 83.830 -36.421 1.00 18.96 ? 578 VAL A N 1 ATOM 4628 C CA . VAL A 1 578 ? 59.073 82.809 -35.725 1.00 17.72 ? 578 VAL A CA 1 ATOM 4629 C C . VAL A 1 578 ? 58.930 81.476 -36.425 1.00 17.82 ? 578 VAL A C 1 ATOM 4630 O O . VAL A 1 578 ? 57.865 81.147 -36.912 1.00 21.05 ? 578 VAL A O 1 ATOM 4631 C CB . VAL A 1 578 ? 58.586 82.701 -34.213 1.00 16.68 ? 578 VAL A CB 1 ATOM 4632 C CG1 . VAL A 1 578 ? 59.364 81.568 -33.472 1.00 16.55 ? 578 VAL A CG1 1 ATOM 4633 C CG2 . VAL A 1 578 ? 58.845 83.984 -33.510 1.00 17.80 ? 578 VAL A CG2 1 ATOM 4634 N N . SER A 1 579 ? 60.021 80.732 -36.515 1.00 20.33 ? 579 SER A N 1 ATOM 4635 C CA . SER A 1 579 ? 59.950 79.422 -37.122 1.00 20.03 ? 579 SER A CA 1 ATOM 4636 C C . SER A 1 579 ? 60.519 78.420 -36.153 1.00 18.70 ? 579 SER A C 1 ATOM 4637 O O . SER A 1 579 ? 61.271 78.767 -35.250 1.00 19.14 ? 579 SER A O 1 ATOM 4638 C CB . SER A 1 579 ? 60.653 79.397 -38.479 1.00 26.20 ? 579 SER A CB 1 ATOM 4639 O OG . SER A 1 579 ? 61.911 79.986 -38.375 1.00 27.28 ? 579 SER A OG 1 ATOM 4640 N N . VAL A 1 580 ? 60.150 77.175 -36.355 1.00 16.51 ? 580 VAL A N 1 ATOM 4641 C CA . VAL A 1 580 ? 60.563 76.122 -35.448 1.00 15.22 ? 580 VAL A CA 1 ATOM 4642 C C . VAL A 1 580 ? 61.440 75.095 -36.121 1.00 16.16 ? 580 VAL A C 1 ATOM 4643 O O . VAL A 1 580 ? 61.193 74.729 -37.278 1.00 18.78 ? 580 VAL A O 1 ATOM 4644 C CB . VAL A 1 580 ? 59.288 75.408 -34.924 1.00 16.25 ? 580 VAL A CB 1 ATOM 4645 C CG1 . VAL A 1 580 ? 59.650 74.355 -33.892 1.00 16.68 ? 580 VAL A CG1 1 ATOM 4646 C CG2 . VAL A 1 580 ? 58.309 76.443 -34.300 1.00 16.54 ? 580 VAL A CG2 1 ATOM 4647 N N . THR A 1 581 ? 62.412 74.590 -35.365 1.00 16.46 ? 581 THR A N 1 ATOM 4648 C CA . THR A 1 581 ? 63.275 73.517 -35.852 1.00 16.48 ? 581 THR A CA 1 ATOM 4649 C C . THR A 1 581 ? 63.455 72.505 -34.726 1.00 17.13 ? 581 THR A C 1 ATOM 4650 O O . THR A 1 581 ? 63.217 72.838 -33.579 1.00 16.82 ? 581 THR A O 1 ATOM 4651 C CB . THR A 1 581 ? 64.715 74.005 -36.272 1.00 19.55 ? 581 THR A CB 1 ATOM 4652 O OG1 . THR A 1 581 ? 65.267 74.896 -35.299 1.00 21.34 ? 581 THR A OG1 1 ATOM 4653 C CG2 . THR A 1 581 ? 64.661 74.755 -37.604 1.00 17.98 ? 581 THR A CG2 1 ATOM 4654 N N . ASP A 1 582 ? 63.754 71.263 -35.064 1.00 16.53 ? 582 ASP A N 1 ATOM 4655 C CA . ASP A 1 582 ? 64.075 70.248 -34.061 1.00 17.96 ? 582 ASP A CA 1 ATOM 4656 C C . ASP A 1 582 ? 65.600 70.359 -33.771 1.00 20.80 ? 582 ASP A C 1 ATOM 4657 O O . ASP A 1 582 ? 66.265 71.230 -34.334 1.00 18.67 ? 582 ASP A O 1 ATOM 4658 C CB . ASP A 1 582 ? 63.610 68.855 -34.520 1.00 20.90 ? 582 ASP A CB 1 ATOM 4659 C CG . ASP A 1 582 ? 64.347 68.308 -35.748 1.00 20.09 ? 582 ASP A CG 1 ATOM 4660 O OD1 . ASP A 1 582 ? 65.403 68.835 -36.133 1.00 20.11 ? 582 ASP A OD1 1 ATOM 4661 O OD2 . ASP A 1 582 ? 63.829 67.296 -36.275 1.00 22.88 ? 582 ASP A OD2 1 ATOM 4662 N N . LEU A 1 583 ? 66.198 69.535 -32.899 1.00 25.44 ? 583 LEU A N 1 ATOM 4663 C CA . LEU A 1 583 ? 67.619 69.818 -32.695 1.00 27.28 ? 583 LEU A CA 1 ATOM 4664 C C . LEU A 1 583 ? 68.544 69.294 -33.788 1.00 28.70 ? 583 LEU A C 1 ATOM 4665 O O . LEU A 1 583 ? 69.769 69.418 -33.664 1.00 31.62 ? 583 LEU A O 1 ATOM 4666 C CB . LEU A 1 583 ? 68.133 69.434 -31.272 1.00 28.22 ? 583 LEU A CB 1 ATOM 4667 C CG . LEU A 1 583 ? 69.106 70.481 -30.630 1.00 25.15 ? 583 LEU A CG 1 ATOM 4668 C CD1 . LEU A 1 583 ? 68.431 71.842 -30.559 1.00 27.82 ? 583 LEU A CD1 1 ATOM 4669 C CD2 . LEU A 1 583 ? 69.529 70.111 -29.204 1.00 29.10 ? 583 LEU A CD2 1 ATOM 4670 N N . ALA A 1 584 ? 67.977 68.730 -34.864 1.00 24.80 ? 584 ALA A N 1 ATOM 4671 C CA . ALA A 1 584 ? 68.822 68.357 -36.001 1.00 21.46 ? 584 ALA A CA 1 ATOM 4672 C C . ALA A 1 584 ? 68.643 69.488 -37.030 1.00 20.21 ? 584 ALA A C 1 ATOM 4673 O O . ALA A 1 584 ? 69.080 69.384 -38.187 1.00 19.90 ? 584 ALA A O 1 ATOM 4674 C CB . ALA A 1 584 ? 68.405 67.020 -36.607 1.00 21.54 ? 584 ALA A CB 1 ATOM 4675 N N . ASN A 1 585 ? 67.992 70.574 -36.617 1.00 20.13 ? 585 ASN A N 1 ATOM 4676 C CA . ASN A 1 585 ? 67.764 71.728 -37.482 1.00 21.06 ? 585 ASN A CA 1 ATOM 4677 C C . ASN A 1 585 ? 66.760 71.453 -38.604 1.00 21.80 ? 585 ASN A C 1 ATOM 4678 O O . ASN A 1 585 ? 66.720 72.175 -39.599 1.00 24.05 ? 585 ASN A O 1 ATOM 4679 C CB . ASN A 1 585 ? 69.091 72.211 -38.089 1.00 24.21 ? 585 ASN A CB 1 ATOM 4680 C CG A ASN A 1 585 ? 69.484 73.587 -37.617 0.50 27.41 ? 585 ASN A CG 1 ATOM 4681 C CG B ASN A 1 585 ? 68.988 73.654 -38.529 0.50 23.58 ? 585 ASN A CG 1 ATOM 4682 O OD1 A ASN A 1 585 ? 68.692 74.533 -37.685 0.50 27.09 ? 585 ASN A OD1 1 ATOM 4683 O OD1 B ASN A 1 585 ? 69.733 74.020 -39.436 0.50 25.91 ? 585 ASN A OD1 1 ATOM 4684 N ND2 A ASN A 1 585 ? 70.714 73.716 -37.139 0.50 31.45 ? 585 ASN A ND2 1 ATOM 4685 N ND2 B ASN A 1 585 ? 68.076 74.451 -37.984 0.50 23.59 ? 585 ASN A ND2 1 ATOM 4686 N N . ASN A 1 586 ? 65.945 70.420 -38.454 1.00 19.06 ? 586 ASN A N 1 ATOM 4687 C CA . ASN A 1 586 ? 64.936 70.105 -39.474 1.00 20.33 ? 586 ASN A CA 1 ATOM 4688 C C . ASN A 1 586 ? 63.783 71.075 -39.221 1.00 21.10 ? 586 ASN A C 1 ATOM 4689 O O . ASN A 1 586 ? 63.338 71.235 -38.098 1.00 19.27 ? 586 ASN A O 1 ATOM 4690 C CB . ASN A 1 586 ? 64.346 68.705 -39.312 1.00 21.08 ? 586 ASN A CB 1 ATOM 4691 C CG . ASN A 1 586 ? 65.366 67.624 -39.438 1.00 20.57 ? 586 ASN A CG 1 ATOM 4692 O OD1 . ASN A 1 586 ? 66.243 67.677 -40.314 1.00 22.18 ? 586 ASN A OD1 1 ATOM 4693 N ND2 . ASN A 1 586 ? 65.267 66.613 -38.572 1.00 22.51 ? 586 ASN A ND2 1 ATOM 4694 N N . PRO A 1 587 ? 63.259 71.717 -40.260 1.00 20.51 ? 587 PRO A N 1 ATOM 4695 C CA . PRO A 1 587 ? 62.141 72.641 -40.054 1.00 19.63 ? 587 PRO A CA 1 ATOM 4696 C C . PRO A 1 587 ? 60.897 71.883 -39.598 1.00 17.93 ? 587 PRO A C 1 ATOM 4697 O O . PRO A 1 587 ? 60.655 70.742 -40.002 1.00 21.73 ? 587 PRO A O 1 ATOM 4698 C CB . PRO A 1 587 ? 61.934 73.269 -41.435 1.00 22.61 ? 587 PRO A CB 1 ATOM 4699 C CG . PRO A 1 587 ? 63.272 73.107 -42.116 1.00 27.08 ? 587 PRO A CG 1 ATOM 4700 C CD . PRO A 1 587 ? 63.744 71.741 -41.650 1.00 22.88 ? 587 PRO A CD 1 ATOM 4701 N N . VAL A 1 588 ? 60.087 72.533 -38.754 1.00 17.65 ? 588 VAL A N 1 ATOM 4702 C CA . VAL A 1 588 ? 58.862 71.944 -38.251 1.00 17.95 ? 588 VAL A CA 1 ATOM 4703 C C . VAL A 1 588 ? 57.750 72.936 -38.615 1.00 15.72 ? 588 VAL A C 1 ATOM 4704 O O . VAL A 1 588 ? 57.882 74.144 -38.350 1.00 18.70 ? 588 VAL A O 1 ATOM 4705 C CB . VAL A 1 588 ? 58.944 71.803 -36.711 1.00 16.98 ? 588 VAL A CB 1 ATOM 4706 C CG1 . VAL A 1 588 ? 57.622 71.325 -36.135 1.00 17.99 ? 588 VAL A CG1 1 ATOM 4707 C CG2 . VAL A 1 588 ? 60.094 70.852 -36.329 1.00 16.35 ? 588 VAL A CG2 1 ATOM 4708 N N . GLU A 1 589 ? 56.693 72.438 -39.246 1.00 16.80 ? 589 GLU A N 1 ATOM 4709 C CA . GLU A 1 589 ? 55.598 73.290 -39.656 1.00 17.67 ? 589 GLU A CA 1 ATOM 4710 C C . GLU A 1 589 ? 54.968 73.920 -38.427 1.00 18.62 ? 589 GLU A C 1 ATOM 4711 O O . GLU A 1 589 ? 54.707 73.228 -37.435 1.00 19.25 ? 589 GLU A O 1 ATOM 4712 C CB . GLU A 1 589 ? 54.543 72.481 -40.401 1.00 22.63 ? 589 GLU A CB 1 ATOM 4713 C CG . GLU A 1 589 ? 53.428 73.343 -40.895 1.00 33.21 ? 589 GLU A CG 1 ATOM 4714 C CD . GLU A 1 589 ? 52.486 72.632 -41.839 1.00 39.43 ? 589 GLU A CD 1 ATOM 4715 O OE1 . GLU A 1 589 ? 52.962 71.804 -42.656 1.00 44.52 ? 589 GLU A OE1 1 ATOM 4716 O OE2 . GLU A 1 589 ? 51.266 72.931 -41.784 1.00 42.25 ? 589 GLU A OE2 1 ATOM 4717 N N . ALA A 1 590 ? 54.699 75.210 -38.485 1.00 16.98 ? 590 ALA A N 1 ATOM 4718 C CA . ALA A 1 590 ? 54.117 75.917 -37.360 1.00 15.86 ? 590 ALA A CA 1 ATOM 4719 C C . ALA A 1 590 ? 53.018 76.838 -37.815 1.00 18.13 ? 590 ALA A C 1 ATOM 4720 O O . ALA A 1 590 ? 52.947 77.169 -39.008 1.00 18.11 ? 590 ALA A O 1 ATOM 4721 C CB . ALA A 1 590 ? 55.161 76.721 -36.635 1.00 17.76 ? 590 ALA A CB 1 ATOM 4722 N N . GLN A 1 591 ? 52.186 77.253 -36.877 1.00 16.65 ? 591 GLN A N 1 ATOM 4723 C CA . GLN A 1 591 ? 51.078 78.179 -37.142 1.00 15.77 ? 591 GLN A CA 1 ATOM 4724 C C . GLN A 1 591 ? 51.149 79.250 -36.089 1.00 16.89 ? 591 GLN A C 1 ATOM 4725 O O . GLN A 1 591 ? 51.393 78.964 -34.899 1.00 17.15 ? 591 GLN A O 1 ATOM 4726 C CB . GLN A 1 591 ? 49.717 77.477 -37.047 1.00 16.43 ? 591 GLN A CB 1 ATOM 4727 C CG . GLN A 1 591 ? 48.532 78.455 -37.041 1.00 15.55 ? 591 GLN A CG 1 ATOM 4728 C CD . GLN A 1 591 ? 47.190 77.741 -36.795 1.00 15.45 ? 591 GLN A CD 1 ATOM 4729 O OE1 . GLN A 1 591 ? 46.942 76.664 -37.349 1.00 16.84 ? 591 GLN A OE1 1 ATOM 4730 N NE2 . GLN A 1 591 ? 46.342 78.338 -35.980 1.00 16.58 ? 591 GLN A NE2 1 ATOM 4731 N N . VAL A 1 592 ? 50.978 80.499 -36.500 1.00 14.71 ? 592 VAL A N 1 ATOM 4732 C CA . VAL A 1 592 ? 50.949 81.597 -35.558 1.00 14.50 ? 592 VAL A CA 1 ATOM 4733 C C . VAL A 1 592 ? 49.548 82.185 -35.552 1.00 16.50 ? 592 VAL A C 1 ATOM 4734 O O . VAL A 1 592 ? 48.898 82.298 -36.611 1.00 17.03 ? 592 VAL A O 1 ATOM 4735 C CB . VAL A 1 592 ? 52.012 82.677 -35.894 1.00 15.55 ? 592 VAL A CB 1 ATOM 4736 C CG1 . VAL A 1 592 ? 51.747 83.924 -35.079 1.00 16.03 ? 592 VAL A CG1 1 ATOM 4737 C CG2 . VAL A 1 592 ? 53.426 82.160 -35.549 1.00 17.17 ? 592 VAL A CG2 1 ATOM 4738 N N . SER A 1 593 ? 49.045 82.478 -34.363 1.00 17.78 ? 593 SER A N 1 ATOM 4739 C CA . SER A 1 593 ? 47.711 83.049 -34.153 1.00 17.51 ? 593 SER A CA 1 ATOM 4740 C C . SER A 1 593 ? 47.869 84.157 -33.170 1.00 17.68 ? 593 SER A C 1 ATOM 4741 O O . SER A 1 593 ? 48.875 84.257 -32.432 1.00 19.44 ? 593 SER A O 1 ATOM 4742 C CB . SER A 1 593 ? 46.720 82.024 -33.523 1.00 18.39 ? 593 SER A CB 1 ATOM 4743 O OG . SER A 1 593 ? 46.565 80.841 -34.304 1.00 18.93 ? 593 SER A OG 1 ATOM 4744 N N . PRO A 1 594 ? 46.873 85.017 -33.092 1.00 18.67 ? 594 PRO A N 1 ATOM 4745 C CA . PRO A 1 594 ? 46.949 86.116 -32.129 1.00 16.62 ? 594 PRO A CA 1 ATOM 4746 C C . PRO A 1 594 ? 46.699 85.599 -30.697 1.00 18.63 ? 594 PRO A C 1 ATOM 4747 O O . PRO A 1 594 ? 46.266 84.446 -30.500 1.00 17.44 ? 594 PRO A O 1 ATOM 4748 C CB . PRO A 1 594 ? 45.804 87.054 -32.554 1.00 17.36 ? 594 PRO A CB 1 ATOM 4749 C CG . PRO A 1 594 ? 45.466 86.594 -33.991 1.00 16.07 ? 594 PRO A CG 1 ATOM 4750 C CD . PRO A 1 594 ? 45.679 85.134 -33.958 1.00 16.26 ? 594 PRO A CD 1 ATOM 4751 N N . VAL A 1 595 ? 47.006 86.442 -29.705 1.00 16.05 ? 595 VAL A N 1 ATOM 4752 C CA . VAL A 1 595 ? 46.676 86.118 -28.329 1.00 17.82 ? 595 VAL A CA 1 ATOM 4753 C C . VAL A 1 595 ? 45.399 86.913 -28.079 1.00 16.95 ? 595 VAL A C 1 ATOM 4754 O O . VAL A 1 595 ? 45.403 88.144 -28.045 1.00 19.25 ? 595 VAL A O 1 ATOM 4755 C CB . VAL A 1 595 ? 47.768 86.564 -27.343 1.00 17.38 ? 595 VAL A CB 1 ATOM 4756 C CG1 . VAL A 1 595 ? 47.245 86.352 -25.927 1.00 18.43 ? 595 VAL A CG1 1 ATOM 4757 C CG2 . VAL A 1 595 ? 49.060 85.734 -27.574 1.00 18.57 ? 595 VAL A CG2 1 ATOM 4758 N N . TRP A 1 596 ? 44.274 86.208 -27.932 1.00 16.84 ? 596 TRP A N 1 ATOM 4759 C CA . TRP A 1 596 ? 42.988 86.845 -27.705 1.00 18.38 ? 596 TRP A CA 1 ATOM 4760 C C . TRP A 1 596 ? 42.562 86.733 -26.257 1.00 20.09 ? 596 TRP A C 1 ATOM 4761 O O . TRP A 1 596 ? 42.652 85.652 -25.667 1.00 20.99 ? 596 TRP A O 1 ATOM 4762 C CB . TRP A 1 596 ? 41.891 86.160 -28.555 1.00 18.80 ? 596 TRP A CB 1 ATOM 4763 C CG . TRP A 1 596 ? 42.031 86.314 -30.023 1.00 17.94 ? 596 TRP A CG 1 ATOM 4764 C CD1 . TRP A 1 596 ? 42.444 85.365 -30.938 1.00 17.51 ? 596 TRP A CD1 1 ATOM 4765 C CD2 . TRP A 1 596 ? 41.747 87.487 -30.773 1.00 18.25 ? 596 TRP A CD2 1 ATOM 4766 N NE1 . TRP A 1 596 ? 42.429 85.891 -32.210 1.00 19.15 ? 596 TRP A NE1 1 ATOM 4767 C CE2 . TRP A 1 596 ? 42.005 87.190 -32.133 1.00 18.95 ? 596 TRP A CE2 1 ATOM 4768 C CE3 . TRP A 1 596 ? 41.295 88.774 -30.428 1.00 19.73 ? 596 TRP A CE3 1 ATOM 4769 C CZ2 . TRP A 1 596 ? 41.827 88.129 -33.143 1.00 20.03 ? 596 TRP A CZ2 1 ATOM 4770 C CZ3 . TRP A 1 596 ? 41.118 89.708 -31.461 1.00 20.43 ? 596 TRP A CZ3 1 ATOM 4771 C CH2 . TRP A 1 596 ? 41.386 89.371 -32.777 1.00 20.68 ? 596 TRP A CH2 1 ATOM 4772 N N . SER A 1 597 ? 42.101 87.834 -25.685 1.00 19.80 ? 597 SER A N 1 ATOM 4773 C CA . SER A 1 597 ? 41.583 87.800 -24.329 1.00 21.15 ? 597 SER A CA 1 ATOM 4774 C C . SER A 1 597 ? 40.174 88.401 -24.352 1.00 21.29 ? 597 SER A C 1 ATOM 4775 O O . SER A 1 597 ? 39.876 89.329 -25.125 1.00 24.01 ? 597 SER A O 1 ATOM 4776 C CB . SER A 1 597 ? 42.494 88.573 -23.372 1.00 25.02 ? 597 SER A CB 1 ATOM 4777 O OG . SER A 1 597 ? 42.611 89.885 -23.813 1.00 29.81 ? 597 SER A OG 1 ATOM 4778 N N . TRP A 1 598 ? 39.300 87.889 -23.500 1.00 21.43 ? 598 TRP A N 1 ATOM 4779 C CA . TRP A 1 598 ? 37.928 88.361 -23.481 1.00 20.25 ? 598 TRP A CA 1 ATOM 4780 C C . TRP A 1 598 ? 37.687 89.310 -22.321 1.00 23.83 ? 598 TRP A C 1 ATOM 4781 O O . TRP A 1 598 ? 38.202 89.117 -21.241 1.00 25.92 ? 598 TRP A O 1 ATOM 4782 C CB . TRP A 1 598 ? 36.943 87.171 -23.409 1.00 20.32 ? 598 TRP A CB 1 ATOM 4783 C CG . TRP A 1 598 ? 36.898 86.410 -24.703 1.00 17.52 ? 598 TRP A CG 1 ATOM 4784 C CD1 . TRP A 1 598 ? 37.801 85.520 -25.142 1.00 17.50 ? 598 TRP A CD1 1 ATOM 4785 C CD2 . TRP A 1 598 ? 35.888 86.492 -25.701 1.00 17.19 ? 598 TRP A CD2 1 ATOM 4786 N NE1 . TRP A 1 598 ? 37.429 85.018 -26.363 1.00 16.82 ? 598 TRP A NE1 1 ATOM 4787 C CE2 . TRP A 1 598 ? 36.250 85.595 -26.730 1.00 15.51 ? 598 TRP A CE2 1 ATOM 4788 C CE3 . TRP A 1 598 ? 34.705 87.231 -25.824 1.00 16.62 ? 598 TRP A CE3 1 ATOM 4789 C CZ2 . TRP A 1 598 ? 35.472 85.411 -27.875 1.00 17.29 ? 598 TRP A CZ2 1 ATOM 4790 C CZ3 . TRP A 1 598 ? 33.922 87.050 -26.961 1.00 15.46 ? 598 TRP A CZ3 1 ATOM 4791 C CH2 . TRP A 1 598 ? 34.318 86.142 -27.974 1.00 17.50 ? 598 TRP A CH2 1 ATOM 4792 N N . HIS A 1 599 ? 36.891 90.333 -22.563 1.00 26.84 ? 599 HIS A N 1 ATOM 4793 C CA . HIS A 1 599 ? 36.654 91.329 -21.533 1.00 31.02 ? 599 HIS A CA 1 ATOM 4794 C C . HIS A 1 599 ? 35.196 91.663 -21.436 1.00 31.83 ? 599 HIS A C 1 ATOM 4795 O O . HIS A 1 599 ? 34.504 91.730 -22.459 1.00 29.90 ? 599 HIS A O 1 ATOM 4796 C CB . HIS A 1 599 ? 37.422 92.603 -21.873 1.00 34.32 ? 599 HIS A CB 1 ATOM 4797 C CG . HIS A 1 599 ? 38.902 92.401 -21.938 1.00 38.21 ? 599 HIS A CG 1 ATOM 4798 N ND1 . HIS A 1 599 ? 39.666 92.140 -20.820 1.00 39.85 ? 599 HIS A ND1 1 ATOM 4799 C CD2 . HIS A 1 599 ? 39.748 92.344 -22.995 1.00 40.52 ? 599 HIS A CD2 1 ATOM 4800 C CE1 . HIS A 1 599 ? 40.918 91.926 -21.186 1.00 40.18 ? 599 HIS A CE1 1 ATOM 4801 N NE2 . HIS A 1 599 ? 40.995 92.044 -22.501 1.00 39.92 ? 599 HIS A NE2 1 ATOM 4802 N N . HIS A 1 600 ? 34.722 91.851 -20.212 1.00 35.41 ? 600 HIS A N 1 ATOM 4803 C CA . HIS A 1 600 ? 33.340 92.245 -20.035 1.00 38.92 ? 600 HIS A CA 1 ATOM 4804 C C . HIS A 1 600 ? 33.455 93.743 -19.983 1.00 39.39 ? 600 HIS A C 1 ATOM 4805 O O . HIS A 1 600 ? 33.831 94.312 -18.955 1.00 40.89 ? 600 HIS A O 1 ATOM 4806 C CB . HIS A 1 600 ? 32.716 91.739 -18.730 1.00 43.02 ? 600 HIS A CB 1 ATOM 4807 C CG . HIS A 1 600 ? 31.370 92.343 -18.460 1.00 48.43 ? 600 HIS A CG 1 ATOM 4808 N ND1 . HIS A 1 600 ? 30.406 92.468 -19.442 1.00 51.24 ? 600 HIS A ND1 1 ATOM 4809 C CD2 . HIS A 1 600 ? 30.849 92.923 -17.350 1.00 50.80 ? 600 HIS A CD2 1 ATOM 4810 C CE1 . HIS A 1 600 ? 29.354 93.101 -18.953 1.00 51.61 ? 600 HIS A CE1 1 ATOM 4811 N NE2 . HIS A 1 600 ? 29.597 93.390 -17.685 1.00 52.00 ? 600 HIS A NE2 1 ATOM 4812 N N . ASP A 1 601 ? 33.156 94.361 -21.117 1.00 39.66 ? 601 ASP A N 1 ATOM 4813 C CA . ASP A 1 601 ? 33.226 95.794 -21.292 1.00 41.09 ? 601 ASP A CA 1 ATOM 4814 C C . ASP A 1 601 ? 32.079 96.461 -20.504 1.00 42.29 ? 601 ASP A C 1 ATOM 4815 O O . ASP A 1 601 ? 30.916 96.323 -20.876 1.00 40.30 ? 601 ASP A O 1 ATOM 4816 C CB . ASP A 1 601 ? 33.100 96.097 -22.788 1.00 41.97 ? 601 ASP A CB 1 ATOM 4817 C CG . ASP A 1 601 ? 33.411 97.541 -23.126 1.00 45.19 ? 601 ASP A CG 1 ATOM 4818 O OD1 . ASP A 1 601 ? 32.982 98.442 -22.375 1.00 44.82 ? 601 ASP A OD1 1 ATOM 4819 O OD2 . ASP A 1 601 ? 34.069 97.792 -24.161 1.00 47.06 ? 601 ASP A OD2 1 ATOM 4820 N N . THR A 1 602 ? 32.405 97.166 -19.419 1.00 43.57 ? 602 THR A N 1 ATOM 4821 C CA . THR A 1 602 ? 31.368 97.837 -18.629 1.00 45.64 ? 602 THR A CA 1 ATOM 4822 C C . THR A 1 602 ? 30.835 99.081 -19.324 1.00 44.87 ? 602 THR A C 1 ATOM 4823 O O . THR A 1 602 ? 29.812 99.630 -18.905 1.00 46.82 ? 602 THR A O 1 ATOM 4824 C CB . THR A 1 602 ? 31.855 98.238 -17.203 1.00 47.95 ? 602 THR A CB 1 ATOM 4825 O OG1 . THR A 1 602 ? 33.089 98.971 -17.293 1.00 50.34 ? 602 THR A OG1 1 ATOM 4826 C CG2 . THR A 1 602 ? 32.026 96.989 -16.319 1.00 48.17 ? 602 THR A CG2 1 ATOM 4827 N N . LEU A 1 603 ? 31.507 99.522 -20.384 1.00 43.29 ? 603 LEU A N 1 ATOM 4828 C CA . LEU A 1 603 ? 31.046 100.692 -21.128 1.00 42.63 ? 603 LEU A CA 1 ATOM 4829 C C . LEU A 1 603 ? 29.969 100.325 -22.141 1.00 40.61 ? 603 LEU A C 1 ATOM 4830 O O . LEU A 1 603 ? 28.919 100.952 -22.199 1.00 41.77 ? 603 LEU A O 1 ATOM 4831 C CB . LEU A 1 603 ? 32.210 101.389 -21.857 1.00 44.43 ? 603 LEU A CB 1 ATOM 4832 C CG . LEU A 1 603 ? 33.272 102.101 -21.007 1.00 46.38 ? 603 LEU A CG 1 ATOM 4833 C CD1 . LEU A 1 603 ? 32.585 103.009 -19.975 1.00 48.50 ? 603 LEU A CD1 1 ATOM 4834 C CD2 . LEU A 1 603 ? 34.138 101.071 -20.296 1.00 47.69 ? 603 LEU A CD2 1 ATOM 4835 N N . THR A 1 604 ? 30.222 99.298 -22.938 1.00 36.23 ? 604 THR A N 1 ATOM 4836 C CA . THR A 1 604 ? 29.263 98.874 -23.948 1.00 33.30 ? 604 THR A CA 1 ATOM 4837 C C . THR A 1 604 ? 28.333 97.768 -23.440 1.00 30.21 ? 604 THR A C 1 ATOM 4838 O O . THR A 1 604 ? 27.364 97.428 -24.116 1.00 29.93 ? 604 THR A O 1 ATOM 4839 C CB . THR A 1 604 ? 29.989 98.333 -25.170 1.00 34.69 ? 604 THR A CB 1 ATOM 4840 O OG1 . THR A 1 604 ? 30.818 97.231 -24.761 1.00 37.01 ? 604 THR A OG1 1 ATOM 4841 C CG2 . THR A 1 604 ? 30.876 99.421 -25.795 1.00 36.14 ? 604 THR A CG2 1 ATOM 4842 N N . LYS A 1 605 ? 28.631 97.215 -22.266 1.00 29.31 ? 605 LYS A N 1 ATOM 4843 C CA . LYS A 1 605 ? 27.833 96.121 -21.692 1.00 29.51 ? 605 LYS A CA 1 ATOM 4844 C C . LYS A 1 605 ? 27.827 94.913 -22.620 1.00 30.29 ? 605 LYS A C 1 ATOM 4845 O O . LYS A 1 605 ? 26.773 94.332 -22.885 1.00 29.28 ? 605 LYS A O 1 ATOM 4846 C CB . LYS A 1 605 ? 26.379 96.544 -21.442 1.00 29.55 ? 605 LYS A CB 1 ATOM 4847 C CG . LYS A 1 605 ? 26.215 97.618 -20.415 1.00 32.39 ? 605 LYS A CG 1 ATOM 4848 C CD . LYS A 1 605 ? 26.722 97.195 -19.027 1.00 34.03 ? 605 LYS A CD 1 ATOM 4849 C CE . LYS A 1 605 ? 26.602 98.380 -18.045 1.00 34.79 ? 605 LYS A CE 1 ATOM 4850 N NZ . LYS A 1 605 ? 27.015 98.051 -16.659 1.00 40.63 ? 605 LYS A NZ 1 ATOM 4851 N N . THR A 1 606 ? 29.000 94.579 -23.147 1.00 27.65 ? 606 THR A N 1 ATOM 4852 C CA . THR A 1 606 ? 29.175 93.410 -24.022 1.00 27.21 ? 606 THR A CA 1 ATOM 4853 C C . THR A 1 606 ? 30.411 92.660 -23.565 1.00 26.30 ? 606 THR A C 1 ATOM 4854 O O . THR A 1 606 ? 31.262 93.209 -22.862 1.00 26.22 ? 606 THR A O 1 ATOM 4855 C CB . THR A 1 606 ? 29.444 93.793 -25.482 1.00 29.85 ? 606 THR A CB 1 ATOM 4856 O OG1 . THR A 1 606 ? 30.600 94.649 -25.535 1.00 31.56 ? 606 THR A OG1 1 ATOM 4857 C CG2 . THR A 1 606 ? 28.227 94.463 -26.108 1.00 30.11 ? 606 THR A CG2 1 ATOM 4858 N N . ILE A 1 607 ? 30.498 91.392 -23.960 1.00 23.94 ? 607 ILE A N 1 ATOM 4859 C CA . ILE A 1 607 ? 31.662 90.566 -23.664 1.00 22.34 ? 607 ILE A CA 1 ATOM 4860 C C . ILE A 1 607 ? 32.323 90.353 -25.043 1.00 21.10 ? 607 ILE A C 1 ATOM 4861 O O . ILE A 1 607 ? 31.747 89.743 -25.958 1.00 22.12 ? 607 ILE A O 1 ATOM 4862 C CB . ILE A 1 607 ? 31.219 89.246 -23.070 1.00 20.82 ? 607 ILE A CB 1 ATOM 4863 C CG1 . ILE A 1 607 ? 30.357 89.508 -21.821 1.00 23.40 ? 607 ILE A CG1 1 ATOM 4864 C CG2 . ILE A 1 607 ? 32.454 88.379 -22.720 1.00 22.47 ? 607 ILE A CG2 1 ATOM 4865 C CD1 . ILE A 1 607 ? 29.603 88.290 -21.353 1.00 25.93 ? 607 ILE A CD1 1 ATOM 4866 N N . HIS A 1 608 ? 33.535 90.868 -25.212 1.00 22.26 ? 608 HIS A N 1 ATOM 4867 C CA . HIS A 1 608 ? 34.166 90.763 -26.516 1.00 21.59 ? 608 HIS A CA 1 ATOM 4868 C C . HIS A 1 608 ? 35.657 90.566 -26.413 1.00 20.74 ? 608 HIS A C 1 ATOM 4869 O O . HIS A 1 608 ? 36.246 90.838 -25.373 1.00 23.40 ? 608 HIS A O 1 ATOM 4870 C CB . HIS A 1 608 ? 33.828 92.003 -27.336 1.00 27.19 ? 608 HIS A CB 1 ATOM 4871 C CG . HIS A 1 608 ? 34.420 93.257 -26.792 1.00 29.33 ? 608 HIS A CG 1 ATOM 4872 N ND1 . HIS A 1 608 ? 34.287 93.645 -25.474 1.00 35.37 ? 608 HIS A ND1 1 ATOM 4873 C CD2 . HIS A 1 608 ? 35.152 94.222 -27.398 1.00 35.33 ? 608 HIS A CD2 1 ATOM 4874 C CE1 . HIS A 1 608 ? 34.909 94.798 -25.292 1.00 35.42 ? 608 HIS A CE1 1 ATOM 4875 N NE2 . HIS A 1 608 ? 35.441 95.171 -26.443 1.00 35.93 ? 608 HIS A NE2 1 ATOM 4876 N N . PRO A 1 609 ? 36.296 90.110 -27.501 1.00 19.65 ? 609 PRO A N 1 ATOM 4877 C CA . PRO A 1 609 ? 37.729 89.860 -27.478 1.00 20.91 ? 609 PRO A CA 1 ATOM 4878 C C . PRO A 1 609 ? 38.620 90.999 -27.890 1.00 23.02 ? 609 PRO A C 1 ATOM 4879 O O . PRO A 1 609 ? 38.274 91.757 -28.802 1.00 24.72 ? 609 PRO A O 1 ATOM 4880 C CB . PRO A 1 609 ? 37.869 88.680 -28.427 1.00 20.53 ? 609 PRO A CB 1 ATOM 4881 C CG . PRO A 1 609 ? 36.883 89.023 -29.504 1.00 21.03 ? 609 PRO A CG 1 ATOM 4882 C CD . PRO A 1 609 ? 35.707 89.699 -28.785 1.00 19.65 ? 609 PRO A CD 1 ATOM 4883 N N . GLN A 1 610 ? 39.766 91.080 -27.218 1.00 21.63 ? 610 GLN A N 1 ATOM 4884 C CA . GLN A 1 610 ? 40.808 92.060 -27.511 1.00 23.78 ? 610 GLN A CA 1 ATOM 4885 C C . GLN A 1 610 ? 42.040 91.257 -27.895 1.00 21.27 ? 610 GLN A C 1 ATOM 4886 O O . GLN A 1 610 ? 42.341 90.258 -27.241 1.00 21.20 ? 610 GLN A O 1 ATOM 4887 C CB . GLN A 1 610 ? 41.126 92.912 -26.279 1.00 29.04 ? 610 GLN A CB 1 ATOM 4888 C CG . GLN A 1 610 ? 39.942 93.764 -25.796 1.00 38.68 ? 610 GLN A CG 1 ATOM 4889 C CD . GLN A 1 610 ? 39.569 94.901 -26.754 1.00 42.50 ? 610 GLN A CD 1 ATOM 4890 O OE1 . GLN A 1 610 ? 38.977 94.686 -27.828 1.00 44.72 ? 610 GLN A OE1 1 ATOM 4891 N NE2 . GLN A 1 610 ? 39.923 96.126 -26.364 1.00 45.05 ? 610 GLN A NE2 1 ATOM 4892 N N . GLY A 1 611 ? 42.735 91.679 -28.944 1.00 19.71 ? 611 GLY A N 1 ATOM 4893 C CA . GLY A 1 611 ? 43.924 90.961 -29.368 1.00 20.45 ? 611 GLY A CA 1 ATOM 4894 C C . GLY A 1 611 ? 45.188 91.687 -28.912 1.00 21.98 ? 611 GLY A C 1 ATOM 4895 O O . GLY A 1 611 ? 45.222 92.926 -28.842 1.00 21.94 ? 611 GLY A O 1 ATOM 4896 N N . SER A 1 612 ? 46.230 90.923 -28.597 1.00 22.67 ? 612 SER A N 1 ATOM 4897 C CA . SER A 1 612 ? 47.477 91.553 -28.198 1.00 22.14 ? 612 SER A CA 1 ATOM 4898 C C . SER A 1 612 ? 48.194 92.133 -29.398 1.00 20.12 ? 612 SER A C 1 ATOM 4899 O O . SER A 1 612 ? 48.159 91.577 -30.490 1.00 22.61 ? 612 SER A O 1 ATOM 4900 C CB . SER A 1 612 ? 48.416 90.533 -27.556 1.00 20.43 ? 612 SER A CB 1 ATOM 4901 O OG . SER A 1 612 ? 49.670 91.147 -27.344 1.00 21.04 ? 612 SER A OG 1 ATOM 4902 N N . THR A 1 613 ? 48.874 93.262 -29.205 1.00 26.65 ? 613 THR A N 1 ATOM 4903 C CA . THR A 1 613 ? 49.633 93.817 -30.315 1.00 27.85 ? 613 THR A CA 1 ATOM 4904 C C . THR A 1 613 ? 51.138 93.585 -30.058 1.00 29.27 ? 613 THR A C 1 ATOM 4905 O O . THR A 1 613 ? 51.982 94.033 -30.847 1.00 31.61 ? 613 THR A O 1 ATOM 4906 C CB . THR A 1 613 ? 49.380 95.319 -30.466 1.00 30.75 ? 613 THR A CB 1 ATOM 4907 O OG1 . THR A 1 613 ? 49.782 95.982 -29.264 1.00 30.33 ? 613 THR A OG1 1 ATOM 4908 C CG2 . THR A 1 613 ? 47.886 95.587 -30.682 1.00 31.47 ? 613 THR A CG2 1 ATOM 4909 N N . THR A 1 614 ? 51.446 92.853 -28.981 1.00 27.58 ? 614 THR A N 1 ATOM 4910 C CA . THR A 1 614 ? 52.828 92.571 -28.589 1.00 29.56 ? 614 THR A CA 1 ATOM 4911 C C . THR A 1 614 ? 53.236 91.108 -28.360 1.00 29.66 ? 614 THR A C 1 ATOM 4912 O O . THR A 1 614 ? 54.434 90.807 -28.289 1.00 30.36 ? 614 THR A O 1 ATOM 4913 C CB . THR A 1 614 ? 53.175 93.336 -27.306 1.00 29.40 ? 614 THR A CB 1 ATOM 4914 O OG1 . THR A 1 614 ? 52.248 93.008 -26.267 1.00 34.49 ? 614 THR A OG1 1 ATOM 4915 C CG2 . THR A 1 614 ? 53.166 94.854 -27.575 1.00 34.79 ? 614 THR A CG2 1 ATOM 4916 N N . LYS A 1 615 ? 52.259 90.212 -28.223 1.00 24.94 ? 615 LYS A N 1 ATOM 4917 C CA . LYS A 1 615 ? 52.514 88.786 -27.976 1.00 23.35 ? 615 LYS A CA 1 ATOM 4918 C C . LYS A 1 615 ? 51.684 88.018 -28.977 1.00 21.19 ? 615 LYS A C 1 ATOM 4919 O O . LYS A 1 615 ? 50.583 88.446 -29.323 1.00 21.09 ? 615 LYS A O 1 ATOM 4920 C CB . LYS A 1 615 ? 52.013 88.323 -26.598 1.00 26.37 ? 615 LYS A CB 1 ATOM 4921 C CG . LYS A 1 615 ? 52.455 89.063 -25.394 1.00 31.87 ? 615 LYS A CG 1 ATOM 4922 C CD . LYS A 1 615 ? 52.119 88.258 -24.131 1.00 31.41 ? 615 LYS A CD 1 ATOM 4923 C CE . LYS A 1 615 ? 50.651 87.975 -23.930 1.00 30.68 ? 615 LYS A CE 1 ATOM 4924 N NZ . LYS A 1 615 ? 50.437 87.771 -22.456 1.00 32.15 ? 615 LYS A NZ 1 ATOM 4925 N N . TYR A 1 616 ? 52.174 86.851 -29.389 1.00 18.94 ? 616 TYR A N 1 ATOM 4926 C CA . TYR A 1 616 ? 51.493 86.015 -30.359 1.00 17.89 ? 616 TYR A CA 1 ATOM 4927 C C . TYR A 1 616 ? 51.637 84.577 -29.938 1.00 17.58 ? 616 TYR A C 1 ATOM 4928 O O . TYR A 1 616 ? 52.536 84.254 -29.152 1.00 19.03 ? 616 TYR A O 1 ATOM 4929 C CB . TYR A 1 616 ? 52.157 86.202 -31.742 1.00 17.46 ? 616 TYR A CB 1 ATOM 4930 C CG . TYR A 1 616 ? 52.177 87.651 -32.114 1.00 21.32 ? 616 TYR A CG 1 ATOM 4931 C CD1 . TYR A 1 616 ? 51.068 88.226 -32.751 1.00 23.73 ? 616 TYR A CD1 1 ATOM 4932 C CD2 . TYR A 1 616 ? 53.239 88.474 -31.726 1.00 21.47 ? 616 TYR A CD2 1 ATOM 4933 C CE1 . TYR A 1 616 ? 51.011 89.572 -32.978 1.00 26.29 ? 616 TYR A CE1 1 ATOM 4934 C CE2 . TYR A 1 616 ? 53.195 89.837 -31.955 1.00 25.15 ? 616 TYR A CE2 1 ATOM 4935 C CZ . TYR A 1 616 ? 52.078 90.373 -32.574 1.00 23.93 ? 616 TYR A CZ 1 ATOM 4936 O OH . TYR A 1 616 ? 52.024 91.736 -32.784 1.00 32.32 ? 616 TYR A OH 1 ATOM 4937 N N . ARG A 1 617 ? 50.783 83.707 -30.449 1.00 16.83 ? 617 ARG A N 1 ATOM 4938 C CA . ARG A 1 617 ? 50.896 82.299 -30.108 1.00 17.64 ? 617 ARG A CA 1 ATOM 4939 C C . ARG A 1 617 ? 51.521 81.526 -31.254 1.00 19.02 ? 617 ARG A C 1 ATOM 4940 O O . ARG A 1 617 ? 51.064 81.673 -32.383 1.00 19.31 ? 617 ARG A O 1 ATOM 4941 C CB . ARG A 1 617 ? 49.524 81.685 -29.857 1.00 21.54 ? 617 ARG A CB 1 ATOM 4942 C CG . ARG A 1 617 ? 48.848 82.030 -28.554 1.00 26.77 ? 617 ARG A CG 1 ATOM 4943 C CD . ARG A 1 617 ? 47.446 81.373 -28.474 1.00 26.88 ? 617 ARG A CD 1 ATOM 4944 N NE . ARG A 1 617 ? 47.496 79.911 -28.539 1.00 25.71 ? 617 ARG A NE 1 ATOM 4945 C CZ . ARG A 1 617 ? 46.816 79.166 -29.412 1.00 27.00 ? 617 ARG A CZ 1 ATOM 4946 N NH1 . ARG A 1 617 ? 46.022 79.734 -30.312 1.00 26.40 ? 617 ARG A NH1 1 ATOM 4947 N NH2 . ARG A 1 617 ? 46.921 77.852 -29.393 1.00 25.60 ? 617 ARG A NH2 1 ATOM 4948 N N . ILE A 1 618 ? 52.555 80.717 -31.001 1.00 15.68 ? 618 ILE A N 1 ATOM 4949 C CA . ILE A 1 618 ? 53.074 79.855 -32.046 1.00 18.47 ? 618 ILE A CA 1 ATOM 4950 C C . ILE A 1 618 ? 52.724 78.432 -31.653 1.00 17.00 ? 618 ILE A C 1 ATOM 4951 O O . ILE A 1 618 ? 52.897 78.035 -30.494 1.00 16.95 ? 618 ILE A O 1 ATOM 4952 C CB . ILE A 1 618 ? 54.562 80.030 -32.299 1.00 17.30 ? 618 ILE A CB 1 ATOM 4953 C CG1 . ILE A 1 618 ? 54.938 79.152 -33.483 1.00 19.49 ? 618 ILE A CG1 1 ATOM 4954 C CG2 . ILE A 1 618 ? 55.412 79.715 -31.040 1.00 17.67 ? 618 ILE A CG2 1 ATOM 4955 C CD1 . ILE A 1 618 ? 56.163 79.601 -34.192 1.00 19.86 ? 618 ILE A CD1 1 ATOM 4956 N N . ILE A 1 619 ? 52.240 77.662 -32.617 1.00 17.09 ? 619 ILE A N 1 ATOM 4957 C CA . ILE A 1 619 ? 51.770 76.304 -32.415 1.00 16.71 ? 619 ILE A CA 1 ATOM 4958 C C . ILE A 1 619 ? 52.481 75.352 -33.353 1.00 17.33 ? 619 ILE A C 1 ATOM 4959 O O . ILE A 1 619 ? 52.650 75.672 -34.525 1.00 16.70 ? 619 ILE A O 1 ATOM 4960 C CB . ILE A 1 619 ? 50.263 76.276 -32.746 1.00 19.99 ? 619 ILE A CB 1 ATOM 4961 C CG1 . ILE A 1 619 ? 49.590 77.392 -31.947 1.00 21.54 ? 619 ILE A CG1 1 ATOM 4962 C CG2 . ILE A 1 619 ? 49.657 74.914 -32.542 1.00 23.03 ? 619 ILE A CG2 1 ATOM 4963 C CD1 . ILE A 1 619 ? 48.437 78.084 -32.731 1.00 24.90 ? 619 ILE A CD1 1 ATOM 4964 N N . PHE A 1 620 ? 52.879 74.170 -32.896 1.00 13.90 ? 620 PHE A N 1 ATOM 4965 C CA . PHE A 1 620 ? 53.533 73.221 -33.789 1.00 14.09 ? 620 PHE A CA 1 ATOM 4966 C C . PHE A 1 620 ? 53.417 71.840 -33.177 1.00 15.06 ? 620 PHE A C 1 ATOM 4967 O O . PHE A 1 620 ? 53.164 71.718 -31.973 1.00 16.69 ? 620 PHE A O 1 ATOM 4968 C CB . PHE A 1 620 ? 55.020 73.589 -33.985 1.00 14.93 ? 620 PHE A CB 1 ATOM 4969 C CG . PHE A 1 620 ? 55.863 73.504 -32.729 1.00 13.97 ? 620 PHE A CG 1 ATOM 4970 C CD1 . PHE A 1 620 ? 56.528 72.318 -32.404 1.00 14.52 ? 620 PHE A CD1 1 ATOM 4971 C CD2 . PHE A 1 620 ? 56.033 74.621 -31.921 1.00 13.87 ? 620 PHE A CD2 1 ATOM 4972 C CE1 . PHE A 1 620 ? 57.388 72.248 -31.266 1.00 13.93 ? 620 PHE A CE1 1 ATOM 4973 C CE2 . PHE A 1 620 ? 56.891 74.567 -30.776 1.00 14.17 ? 620 PHE A CE2 1 ATOM 4974 C CZ . PHE A 1 620 ? 57.552 73.375 -30.480 1.00 15.95 ? 620 PHE A CZ 1 ATOM 4975 N N . LYS A 1 621 ? 53.619 70.814 -33.977 1.00 14.95 ? 621 LYS A N 1 ATOM 4976 C CA . LYS A 1 621 ? 53.523 69.478 -33.455 1.00 16.90 ? 621 LYS A CA 1 ATOM 4977 C C . LYS A 1 621 ? 54.847 69.022 -32.840 1.00 16.92 ? 621 LYS A C 1 ATOM 4978 O O . LYS A 1 621 ? 55.901 69.054 -33.490 1.00 18.26 ? 621 LYS A O 1 ATOM 4979 C CB . LYS A 1 621 ? 53.116 68.533 -34.611 1.00 19.00 ? 621 LYS A CB 1 ATOM 4980 C CG . LYS A 1 621 ? 52.726 67.162 -34.124 1.00 24.37 ? 621 LYS A CG 1 ATOM 4981 C CD . LYS A 1 621 ? 51.814 66.476 -35.129 1.00 31.71 ? 621 LYS A CD 1 ATOM 4982 C CE . LYS A 1 621 ? 52.424 66.477 -36.515 1.00 33.33 ? 621 LYS A CE 1 ATOM 4983 N NZ . LYS A 1 621 ? 51.593 65.644 -37.462 1.00 37.52 ? 621 LYS A NZ 1 ATOM 4984 N N . ALA A 1 622 ? 54.802 68.598 -31.570 1.00 15.12 ? 622 ALA A N 1 ATOM 4985 C CA . ALA A 1 622 ? 56.004 68.052 -30.944 1.00 15.40 ? 622 ALA A CA 1 ATOM 4986 C C . ALA A 1 622 ? 55.889 66.521 -30.918 1.00 15.19 ? 622 ALA A C 1 ATOM 4987 O O . ALA A 1 622 ? 54.813 65.969 -30.655 1.00 17.95 ? 622 ALA A O 1 ATOM 4988 C CB . ALA A 1 622 ? 56.146 68.567 -29.513 1.00 14.95 ? 622 ALA A CB 1 ATOM 4989 N N . ARG A 1 623 ? 56.966 65.844 -31.285 1.00 14.35 ? 623 ARG A N 1 ATOM 4990 C CA . ARG A 1 623 ? 56.986 64.380 -31.290 1.00 15.53 ? 623 ARG A CA 1 ATOM 4991 C C . ARG A 1 623 ? 57.968 64.012 -30.188 1.00 14.82 ? 623 ARG A C 1 ATOM 4992 O O . ARG A 1 623 ? 59.143 64.359 -30.231 1.00 16.95 ? 623 ARG A O 1 ATOM 4993 C CB . ARG A 1 623 ? 57.445 63.892 -32.665 1.00 17.73 ? 623 ARG A CB 1 ATOM 4994 C CG . ARG A 1 623 ? 57.621 62.397 -32.735 1.00 21.15 ? 623 ARG A CG 1 ATOM 4995 C CD . ARG A 1 623 ? 57.772 61.877 -34.195 1.00 22.49 ? 623 ARG A CD 1 ATOM 4996 N NE . ARG A 1 623 ? 57.883 60.411 -34.169 1.00 25.58 ? 623 ARG A NE 1 ATOM 4997 C CZ . ARG A 1 623 ? 59.035 59.766 -33.999 1.00 27.18 ? 623 ARG A CZ 1 ATOM 4998 N NH1 . ARG A 1 623 ? 60.184 60.440 -33.870 1.00 30.49 ? 623 ARG A NH1 1 ATOM 4999 N NH2 . ARG A 1 623 ? 59.034 58.445 -33.856 1.00 30.68 ? 623 ARG A NH2 1 ATOM 5000 N N . VAL A 1 624 ? 57.443 63.303 -29.185 1.00 14.35 ? 624 VAL A N 1 ATOM 5001 C CA . VAL A 1 624 ? 58.219 63.017 -27.974 1.00 13.72 ? 624 VAL A CA 1 ATOM 5002 C C . VAL A 1 624 ? 58.256 61.533 -27.668 1.00 12.91 ? 624 VAL A C 1 ATOM 5003 O O . VAL A 1 624 ? 57.239 60.876 -27.735 1.00 13.72 ? 624 VAL A O 1 ATOM 5004 C CB . VAL A 1 624 ? 57.547 63.782 -26.814 1.00 14.11 ? 624 VAL A CB 1 ATOM 5005 C CG1 . VAL A 1 624 ? 58.466 63.780 -25.605 1.00 14.87 ? 624 VAL A CG1 1 ATOM 5006 C CG2 . VAL A 1 624 ? 57.230 65.245 -27.241 1.00 14.91 ? 624 VAL A CG2 1 ATOM 5007 N N . PRO A 1 625 ? 59.453 61.009 -27.294 1.00 13.92 ? 625 PRO A N 1 ATOM 5008 C CA . PRO A 1 625 ? 59.559 59.577 -26.997 1.00 13.59 ? 625 PRO A CA 1 ATOM 5009 C C . PRO A 1 625 ? 58.731 59.123 -25.799 1.00 14.80 ? 625 PRO A C 1 ATOM 5010 O O . PRO A 1 625 ? 58.294 59.936 -24.977 1.00 13.41 ? 625 PRO A O 1 ATOM 5011 C CB . PRO A 1 625 ? 61.037 59.368 -26.668 1.00 16.29 ? 625 PRO A CB 1 ATOM 5012 C CG . PRO A 1 625 ? 61.761 60.552 -27.308 1.00 15.93 ? 625 PRO A CG 1 ATOM 5013 C CD . PRO A 1 625 ? 60.753 61.693 -27.157 1.00 14.77 ? 625 PRO A CD 1 ATOM 5014 N N . PRO A 1 626 ? 58.536 57.818 -25.681 1.00 13.94 ? 626 PRO A N 1 ATOM 5015 C CA . PRO A 1 626 ? 57.773 57.284 -24.528 1.00 14.44 ? 626 PRO A CA 1 ATOM 5016 C C . PRO A 1 626 ? 58.575 57.710 -23.271 1.00 14.49 ? 626 PRO A C 1 ATOM 5017 O O . PRO A 1 626 ? 59.816 57.532 -23.189 1.00 14.92 ? 626 PRO A O 1 ATOM 5018 C CB . PRO A 1 626 ? 57.892 55.764 -24.689 1.00 13.47 ? 626 PRO A CB 1 ATOM 5019 C CG . PRO A 1 626 ? 58.194 55.574 -26.231 1.00 14.01 ? 626 PRO A CG 1 ATOM 5020 C CD . PRO A 1 626 ? 59.083 56.738 -26.546 1.00 14.70 ? 626 PRO A CD 1 ATOM 5021 N N . MET A 1 627 ? 57.871 58.266 -22.271 1.00 12.04 ? 627 MET A N 1 ATOM 5022 C CA . MET A 1 627 ? 58.499 58.681 -20.993 1.00 12.33 ? 627 MET A CA 1 ATOM 5023 C C . MET A 1 627 ? 59.791 59.429 -21.256 1.00 12.47 ? 627 MET A C 1 ATOM 5024 O O . MET A 1 627 ? 60.798 59.282 -20.555 1.00 13.18 ? 627 MET A O 1 ATOM 5025 C CB . MET A 1 627 ? 58.775 57.442 -20.122 1.00 13.38 ? 627 MET A CB 1 ATOM 5026 C CG . MET A 1 627 ? 57.501 56.747 -19.736 1.00 12.68 ? 627 MET A CG 1 ATOM 5027 S SD . MET A 1 627 ? 57.697 55.049 -19.080 1.00 15.86 ? 627 MET A SD 1 ATOM 5028 C CE . MET A 1 627 ? 58.596 55.372 -17.660 1.00 16.05 ? 627 MET A CE 1 ATOM 5029 N N . GLY A 1 628 ? 59.722 60.308 -22.263 1.00 12.99 ? 628 GLY A N 1 ATOM 5030 C CA . GLY A 1 628 ? 60.926 60.982 -22.706 1.00 13.94 ? 628 GLY A CA 1 ATOM 5031 C C . GLY A 1 628 ? 60.819 62.480 -22.925 1.00 13.90 ? 628 GLY A C 1 ATOM 5032 O O . GLY A 1 628 ? 59.826 63.112 -22.539 1.00 12.62 ? 628 GLY A O 1 ATOM 5033 N N . LEU A 1 629 ? 61.851 63.019 -23.583 1.00 13.53 ? 629 LEU A N 1 ATOM 5034 C CA . LEU A 1 629 ? 61.974 64.468 -23.809 1.00 13.00 ? 629 LEU A CA 1 ATOM 5035 C C . LEU A 1 629 ? 62.408 64.758 -25.219 1.00 14.72 ? 629 LEU A C 1 ATOM 5036 O O . LEU A 1 629 ? 63.177 63.980 -25.823 1.00 14.86 ? 629 LEU A O 1 ATOM 5037 C CB . LEU A 1 629 ? 63.049 65.051 -22.902 1.00 12.31 ? 629 LEU A CB 1 ATOM 5038 C CG . LEU A 1 629 ? 62.821 64.888 -21.395 1.00 12.92 ? 629 LEU A CG 1 ATOM 5039 C CD1 . LEU A 1 629 ? 64.097 65.181 -20.650 1.00 13.80 ? 629 LEU A CD1 1 ATOM 5040 C CD2 . LEU A 1 629 ? 61.717 65.861 -20.955 1.00 14.36 ? 629 LEU A CD2 1 ATOM 5041 N N . ALA A 1 630 ? 61.934 65.881 -25.742 1.00 13.26 ? 630 ALA A N 1 ATOM 5042 C CA . ALA A 1 630 ? 62.307 66.292 -27.110 1.00 14.49 ? 630 ALA A CA 1 ATOM 5043 C C . ALA A 1 630 ? 62.538 67.793 -27.070 1.00 15.47 ? 630 ALA A C 1 ATOM 5044 O O . ALA A 1 630 ? 61.757 68.554 -26.501 1.00 14.87 ? 630 ALA A O 1 ATOM 5045 C CB . ALA A 1 630 ? 61.207 65.941 -28.102 1.00 15.48 ? 630 ALA A CB 1 ATOM 5046 N N . THR A 1 631 ? 63.614 68.215 -27.726 1.00 13.98 ? 631 THR A N 1 ATOM 5047 C CA . THR A 1 631 ? 64.000 69.636 -27.755 1.00 15.78 ? 631 THR A CA 1 ATOM 5048 C C . THR A 1 631 ? 63.739 70.288 -29.097 1.00 14.95 ? 631 THR A C 1 ATOM 5049 O O . THR A 1 631 ? 64.024 69.688 -30.155 1.00 16.94 ? 631 THR A O 1 ATOM 5050 C CB . THR A 1 631 ? 65.509 69.768 -27.467 1.00 16.11 ? 631 THR A CB 1 ATOM 5051 O OG1 . THR A 1 631 ? 65.815 69.041 -26.260 1.00 15.87 ? 631 THR A OG1 1 ATOM 5052 C CG2 . THR A 1 631 ? 65.940 71.244 -27.301 1.00 17.81 ? 631 THR A CG2 1 ATOM 5053 N N . TYR A 1 632 ? 63.215 71.504 -29.048 1.00 14.79 ? 632 TYR A N 1 ATOM 5054 C CA . TYR A 1 632 ? 62.966 72.300 -30.252 1.00 14.90 ? 632 TYR A CA 1 ATOM 5055 C C . TYR A 1 632 ? 63.540 73.689 -30.075 1.00 15.71 ? 632 TYR A C 1 ATOM 5056 O O . TYR A 1 632 ? 63.879 74.122 -28.979 1.00 15.40 ? 632 TYR A O 1 ATOM 5057 C CB . TYR A 1 632 ? 61.469 72.375 -30.559 1.00 15.21 ? 632 TYR A CB 1 ATOM 5058 C CG . TYR A 1 632 ? 60.873 71.057 -30.960 1.00 15.68 ? 632 TYR A CG 1 ATOM 5059 C CD1 . TYR A 1 632 ? 60.542 70.094 -29.995 1.00 16.17 ? 632 TYR A CD1 1 ATOM 5060 C CD2 . TYR A 1 632 ? 60.632 70.757 -32.314 1.00 15.60 ? 632 TYR A CD2 1 ATOM 5061 C CE1 . TYR A 1 632 ? 59.999 68.880 -30.368 1.00 16.68 ? 632 TYR A CE1 1 ATOM 5062 C CE2 . TYR A 1 632 ? 60.096 69.534 -32.701 1.00 17.31 ? 632 TYR A CE2 1 ATOM 5063 C CZ . TYR A 1 632 ? 59.781 68.591 -31.719 1.00 15.90 ? 632 TYR A CZ 1 ATOM 5064 O OH . TYR A 1 632 ? 59.302 67.366 -32.111 1.00 19.13 ? 632 TYR A OH 1 ATOM 5065 N N . VAL A 1 633 ? 63.700 74.393 -31.202 1.00 14.22 ? 633 VAL A N 1 ATOM 5066 C CA . VAL A 1 633 ? 64.248 75.740 -31.181 1.00 14.20 ? 633 VAL A CA 1 ATOM 5067 C C . VAL A 1 633 ? 63.305 76.705 -31.913 1.00 13.33 ? 633 VAL A C 1 ATOM 5068 O O . VAL A 1 633 ? 62.815 76.375 -32.993 1.00 15.36 ? 633 VAL A O 1 ATOM 5069 C CB . VAL A 1 633 ? 65.642 75.779 -31.880 1.00 15.10 ? 633 VAL A CB 1 ATOM 5070 C CG1 . VAL A 1 633 ? 66.226 77.174 -31.838 1.00 17.99 ? 633 VAL A CG1 1 ATOM 5071 C CG2 . VAL A 1 633 ? 66.578 74.788 -31.195 1.00 18.71 ? 633 VAL A CG2 1 ATOM 5072 N N . LEU A 1 634 ? 63.029 77.847 -31.310 1.00 14.43 ? 634 LEU A N 1 ATOM 5073 C CA . LEU A 1 634 ? 62.181 78.891 -31.917 1.00 15.78 ? 634 LEU A CA 1 ATOM 5074 C C . LEU A 1 634 ? 63.136 80.009 -32.295 1.00 16.63 ? 634 LEU A C 1 ATOM 5075 O O . LEU A 1 634 ? 63.913 80.481 -31.441 1.00 15.18 ? 634 LEU A O 1 ATOM 5076 C CB . LEU A 1 634 ? 61.163 79.447 -30.913 1.00 16.45 ? 634 LEU A CB 1 ATOM 5077 C CG . LEU A 1 634 ? 60.240 78.444 -30.207 1.00 24.01 ? 634 LEU A CG 1 ATOM 5078 C CD1 . LEU A 1 634 ? 59.016 79.189 -29.633 1.00 21.88 ? 634 LEU A CD1 1 ATOM 5079 C CD2 . LEU A 1 634 ? 59.816 77.338 -31.095 1.00 25.74 ? 634 LEU A CD2 1 ATOM 5080 N N . THR A 1 635 ? 63.083 80.435 -33.573 1.00 16.10 ? 635 THR A N 1 ATOM 5081 C CA . THR A 1 635 ? 64.020 81.445 -34.071 1.00 15.93 ? 635 THR A CA 1 ATOM 5082 C C . THR A 1 635 ? 63.247 82.579 -34.742 1.00 16.41 ? 635 THR A C 1 ATOM 5083 O O . THR A 1 635 ? 62.312 82.354 -35.527 1.00 17.91 ? 635 THR A O 1 ATOM 5084 C CB . THR A 1 635 ? 64.961 80.806 -35.105 1.00 17.82 ? 635 THR A CB 1 ATOM 5085 O OG1 . THR A 1 635 ? 65.635 79.672 -34.524 1.00 18.05 ? 635 THR A OG1 1 ATOM 5086 C CG2 . THR A 1 635 ? 65.984 81.833 -35.608 1.00 18.00 ? 635 THR A CG2 1 ATOM 5087 N N . ILE A 1 636 ? 63.668 83.801 -34.450 1.00 17.56 ? 636 ILE A N 1 ATOM 5088 C CA . ILE A 1 636 ? 62.972 84.948 -35.050 1.00 18.83 ? 636 ILE A CA 1 ATOM 5089 C C . ILE A 1 636 ? 63.591 85.309 -36.397 1.00 22.45 ? 636 ILE A C 1 ATOM 5090 O O . ILE A 1 636 ? 64.766 85.016 -36.653 1.00 21.91 ? 636 ILE A O 1 ATOM 5091 C CB . ILE A 1 636 ? 63.035 86.166 -34.109 1.00 18.85 ? 636 ILE A CB 1 ATOM 5092 C CG1 . ILE A 1 636 ? 62.116 87.283 -34.619 1.00 20.18 ? 636 ILE A CG1 1 ATOM 5093 C CG2 . ILE A 1 636 ? 64.470 86.722 -34.006 1.00 20.46 ? 636 ILE A CG2 1 ATOM 5094 C CD1 . ILE A 1 636 ? 62.045 88.448 -33.638 1.00 22.14 ? 636 ILE A CD1 1 ATOM 5095 N N . SER A 1 637 ? 62.762 85.853 -37.286 1.00 21.99 ? 637 SER A N 1 ATOM 5096 C CA . SER A 1 637 ? 63.260 86.339 -38.577 1.00 25.30 ? 637 SER A CA 1 ATOM 5097 C C . SER A 1 637 ? 62.630 87.707 -38.821 1.00 27.98 ? 637 SER A C 1 ATOM 5098 O O . SER A 1 637 ? 61.709 88.099 -38.126 1.00 25.90 ? 637 SER A O 1 ATOM 5099 C CB . SER A 1 637 ? 62.948 85.370 -39.727 1.00 30.95 ? 637 SER A CB 1 ATOM 5100 O OG . SER A 1 637 ? 61.575 85.072 -39.791 1.00 35.46 ? 637 SER A OG 1 ATOM 5101 N N . ASP A 1 638 ? 63.139 88.454 -39.800 1.00 31.01 ? 638 ASP A N 1 ATOM 5102 C CA . ASP A 1 638 ? 62.584 89.783 -40.018 1.00 34.56 ? 638 ASP A CA 1 ATOM 5103 C C . ASP A 1 638 ? 61.262 89.764 -40.798 1.00 34.44 ? 638 ASP A C 1 ATOM 5104 O O . ASP A 1 638 ? 60.522 90.755 -40.794 1.00 35.99 ? 638 ASP A O 1 ATOM 5105 C CB . ASP A 1 638 ? 63.629 90.692 -40.695 1.00 39.13 ? 638 ASP A CB 1 ATOM 5106 C CG . ASP A 1 638 ? 63.757 90.438 -42.174 1.00 43.62 ? 638 ASP A CG 1 ATOM 5107 O OD1 . ASP A 1 638 ? 63.862 89.253 -42.574 1.00 45.28 ? 638 ASP A OD1 1 ATOM 5108 O OD2 . ASP A 1 638 ? 63.756 91.437 -42.945 1.00 48.46 ? 638 ASP A OD2 1 ATOM 5109 N N . SER A 1 639 ? 60.949 88.622 -41.413 1.00 31.93 ? 639 SER A N 1 ATOM 5110 C CA . SER A 1 639 ? 59.729 88.478 -42.194 1.00 31.69 ? 639 SER A CA 1 ATOM 5111 C C . SER A 1 639 ? 59.135 87.074 -42.085 1.00 30.53 ? 639 SER A C 1 ATOM 5112 O O . SER A 1 639 ? 59.732 86.184 -41.472 1.00 27.16 ? 639 SER A O 1 ATOM 5113 C CB . SER A 1 639 ? 60.014 88.791 -43.669 1.00 31.29 ? 639 SER A CB 1 ATOM 5114 O OG . SER A 1 639 ? 61.017 87.918 -44.158 1.00 34.33 ? 639 SER A OG 1 ATOM 5115 N N . LYS A 1 640 ? 57.958 86.890 -42.674 1.00 28.83 ? 640 LYS A N 1 ATOM 5116 C CA . LYS A 1 640 ? 57.282 85.597 -42.649 1.00 29.38 ? 640 LYS A CA 1 ATOM 5117 C C . LYS A 1 640 ? 58.203 84.432 -43.041 1.00 28.18 ? 640 LYS A C 1 ATOM 5118 O O . LYS A 1 640 ? 58.747 84.385 -44.160 1.00 29.02 ? 640 LYS A O 1 ATOM 5119 C CB . LYS A 1 640 ? 56.072 85.585 -43.595 1.00 30.28 ? 640 LYS A CB 1 ATOM 5120 C CG . LYS A 1 640 ? 54.936 86.549 -43.274 1.00 35.99 ? 640 LYS A CG 1 ATOM 5121 C CD . LYS A 1 640 ? 53.627 86.106 -43.970 1.00 38.91 ? 640 LYS A CD 1 ATOM 5122 C CE . LYS A 1 640 ? 53.741 86.033 -45.492 1.00 41.17 ? 640 LYS A CE 1 ATOM 5123 N NZ . LYS A 1 640 ? 53.641 87.369 -46.148 1.00 43.20 ? 640 LYS A NZ 1 ATOM 5124 N N . PRO A 1 641 ? 58.390 83.461 -42.123 1.00 26.11 ? 641 PRO A N 1 ATOM 5125 C CA . PRO A 1 641 ? 59.216 82.264 -42.300 1.00 25.63 ? 641 PRO A CA 1 ATOM 5126 C C . PRO A 1 641 ? 58.532 81.321 -43.274 1.00 25.52 ? 641 PRO A C 1 ATOM 5127 O O . PRO A 1 641 ? 57.300 81.233 -43.318 1.00 23.84 ? 641 PRO A O 1 ATOM 5128 C CB . PRO A 1 641 ? 59.224 81.622 -40.908 1.00 27.47 ? 641 PRO A CB 1 ATOM 5129 C CG . PRO A 1 641 ? 58.948 82.773 -40.004 1.00 26.22 ? 641 PRO A CG 1 ATOM 5130 C CD . PRO A 1 641 ? 57.919 83.571 -40.731 1.00 25.89 ? 641 PRO A CD 1 ATOM 5131 N N . GLU A 1 642 ? 59.330 80.569 -44.010 1.00 24.95 ? 642 GLU A N 1 ATOM 5132 C CA . GLU A 1 642 ? 58.795 79.631 -44.971 1.00 25.47 ? 642 GLU A CA 1 ATOM 5133 C C . GLU A 1 642 ? 57.885 78.545 -44.401 1.00 26.54 ? 642 GLU A C 1 ATOM 5134 O O . GLU A 1 642 ? 56.914 78.147 -45.032 1.00 27.54 ? 642 GLU A O 1 ATOM 5135 C CB . GLU A 1 642 ? 59.959 78.960 -45.714 1.00 28.94 ? 642 GLU A CB 1 ATOM 5136 C CG . GLU A 1 642 ? 59.549 77.862 -46.643 1.00 34.70 ? 642 GLU A CG 1 ATOM 5137 C CD . GLU A 1 642 ? 60.743 77.288 -47.395 1.00 40.07 ? 642 GLU A CD 1 ATOM 5138 O OE1 . GLU A 1 642 ? 61.845 77.900 -47.319 1.00 43.05 ? 642 GLU A OE1 1 ATOM 5139 O OE2 . GLU A 1 642 ? 60.575 76.229 -48.052 1.00 42.97 ? 642 GLU A OE2 1 ATOM 5140 N N . HIS A 1 643 ? 58.191 78.088 -43.188 1.00 24.46 ? 643 HIS A N 1 ATOM 5141 C CA . HIS A 1 643 ? 57.435 76.984 -42.596 1.00 22.49 ? 643 HIS A CA 1 ATOM 5142 C C . HIS A 1 643 ? 56.446 77.361 -41.509 1.00 22.27 ? 643 HIS A C 1 ATOM 5143 O O . HIS A 1 643 ? 56.043 76.497 -40.730 1.00 20.33 ? 643 HIS A O 1 ATOM 5144 C CB . HIS A 1 643 ? 58.411 75.941 -42.059 1.00 23.02 ? 643 HIS A CB 1 ATOM 5145 C CG . HIS A 1 643 ? 59.279 75.362 -43.129 1.00 22.26 ? 643 HIS A CG 1 ATOM 5146 N ND1 . HIS A 1 643 ? 58.840 74.366 -43.965 1.00 29.06 ? 643 HIS A ND1 1 ATOM 5147 C CD2 . HIS A 1 643 ? 60.532 75.673 -43.531 1.00 23.93 ? 643 HIS A CD2 1 ATOM 5148 C CE1 . HIS A 1 643 ? 59.790 74.081 -44.841 1.00 27.23 ? 643 HIS A CE1 1 ATOM 5149 N NE2 . HIS A 1 643 ? 60.827 74.860 -44.595 1.00 25.78 ? 643 HIS A NE2 1 ATOM 5150 N N . THR A 1 644 ? 56.099 78.638 -41.455 1.00 18.91 ? 644 THR A N 1 ATOM 5151 C CA . THR A 1 644 ? 55.135 79.158 -40.510 1.00 19.15 ? 644 THR A CA 1 ATOM 5152 C C . THR A 1 644 ? 53.992 79.814 -41.276 1.00 20.61 ? 644 THR A C 1 ATOM 5153 O O . THR A 1 644 ? 54.230 80.639 -42.177 1.00 21.02 ? 644 THR A O 1 ATOM 5154 C CB . THR A 1 644 ? 55.772 80.184 -39.571 1.00 19.04 ? 644 THR A CB 1 ATOM 5155 O OG1 . THR A 1 644 ? 56.834 79.527 -38.829 1.00 20.35 ? 644 THR A OG1 1 ATOM 5156 C CG2 . THR A 1 644 ? 54.727 80.764 -38.556 1.00 19.88 ? 644 THR A CG2 1 ATOM 5157 N N . SER A 1 645 ? 52.771 79.396 -40.953 1.00 18.28 ? 645 SER A N 1 ATOM 5158 C CA . SER A 1 645 ? 51.554 79.937 -41.545 1.00 18.27 ? 645 SER A CA 1 ATOM 5159 C C . SER A 1 645 ? 50.856 80.796 -40.491 1.00 18.21 ? 645 SER A C 1 ATOM 5160 O O . SER A 1 645 ? 51.197 80.732 -39.313 1.00 19.19 ? 645 SER A O 1 ATOM 5161 C CB . SER A 1 645 ? 50.614 78.830 -42.006 1.00 20.61 ? 645 SER A CB 1 ATOM 5162 O OG . SER A 1 645 ? 50.078 78.114 -40.877 1.00 21.10 ? 645 SER A OG 1 ATOM 5163 N N . TYR A 1 646 ? 49.883 81.588 -40.910 1.00 16.68 ? 646 TYR A N 1 ATOM 5164 C CA . TYR A 1 646 ? 49.165 82.494 -40.025 1.00 16.95 ? 646 TYR A CA 1 ATOM 5165 C C . TYR A 1 646 ? 47.670 82.299 -40.112 1.00 18.52 ? 646 TYR A C 1 ATOM 5166 O O . TYR A 1 646 ? 47.107 82.237 -41.195 1.00 20.91 ? 646 TYR A O 1 ATOM 5167 C CB . TYR A 1 646 ? 49.505 83.933 -40.426 1.00 19.13 ? 646 TYR A CB 1 ATOM 5168 C CG . TYR A 1 646 ? 50.975 84.209 -40.221 1.00 19.32 ? 646 TYR A CG 1 ATOM 5169 C CD1 . TYR A 1 646 ? 51.913 83.909 -41.207 1.00 19.69 ? 646 TYR A CD1 1 ATOM 5170 C CD2 . TYR A 1 646 ? 51.433 84.648 -38.987 1.00 19.78 ? 646 TYR A CD2 1 ATOM 5171 C CE1 . TYR A 1 646 ? 53.275 84.032 -40.963 1.00 21.84 ? 646 TYR A CE1 1 ATOM 5172 C CE2 . TYR A 1 646 ? 52.772 84.777 -38.734 1.00 19.78 ? 646 TYR A CE2 1 ATOM 5173 C CZ . TYR A 1 646 ? 53.698 84.463 -39.723 1.00 20.24 ? 646 TYR A CZ 1 ATOM 5174 O OH . TYR A 1 646 ? 55.042 84.535 -39.422 1.00 22.94 ? 646 TYR A OH 1 ATOM 5175 N N . ALA A 1 647 ? 47.012 82.171 -38.955 1.00 16.81 ? 647 ALA A N 1 ATOM 5176 C CA . ALA A 1 647 ? 45.590 81.979 -38.935 1.00 16.05 ? 647 ALA A CA 1 ATOM 5177 C C . ALA A 1 647 ? 44.817 83.203 -39.375 1.00 16.16 ? 647 ALA A C 1 ATOM 5178 O O . ALA A 1 647 ? 45.253 84.340 -39.215 1.00 17.65 ? 647 ALA A O 1 ATOM 5179 C CB . ALA A 1 647 ? 45.127 81.586 -37.528 1.00 17.53 ? 647 ALA A CB 1 ATOM 5180 N N . SER A 1 648 ? 43.669 82.949 -39.979 1.00 16.19 ? 648 SER A N 1 ATOM 5181 C CA . SER A 1 648 ? 42.800 84.067 -40.295 1.00 15.90 ? 648 SER A CA 1 ATOM 5182 C C . SER A 1 648 ? 41.911 84.248 -39.043 1.00 16.59 ? 648 SER A C 1 ATOM 5183 O O . SER A 1 648 ? 41.728 83.311 -38.248 1.00 16.65 ? 648 SER A O 1 ATOM 5184 C CB . SER A 1 648 ? 41.933 83.726 -41.513 1.00 19.68 ? 648 SER A CB 1 ATOM 5185 O OG . SER A 1 648 ? 41.093 82.625 -41.255 1.00 24.87 ? 648 SER A OG 1 ATOM 5186 N N . ASN A 1 649 ? 41.304 85.417 -38.888 1.00 15.44 ? 649 ASN A N 1 ATOM 5187 C CA . ASN A 1 649 ? 40.437 85.696 -37.740 1.00 15.92 ? 649 ASN A CA 1 ATOM 5188 C C . ASN A 1 649 ? 39.219 86.445 -38.203 1.00 16.86 ? 649 ASN A C 1 ATOM 5189 O O . ASN A 1 649 ? 39.344 87.427 -38.960 1.00 17.56 ? 649 ASN A O 1 ATOM 5190 C CB . ASN A 1 649 ? 41.157 86.510 -36.677 1.00 17.50 ? 649 ASN A CB 1 ATOM 5191 C CG . ASN A 1 649 ? 42.354 85.757 -36.090 1.00 17.52 ? 649 ASN A CG 1 ATOM 5192 O OD1 . ASN A 1 649 ? 42.213 84.972 -35.136 1.00 16.97 ? 649 ASN A OD1 1 ATOM 5193 N ND2 . ASN A 1 649 ? 43.520 85.929 -36.710 1.00 17.63 ? 649 ASN A ND2 1 ATOM 5194 N N . LEU A 1 650 ? 38.058 86.003 -37.749 1.00 16.10 ? 650 LEU A N 1 ATOM 5195 C CA . LEU A 1 650 ? 36.772 86.586 -38.153 1.00 16.93 ? 650 LEU A CA 1 ATOM 5196 C C . LEU A 1 650 ? 35.942 86.861 -36.908 1.00 17.43 ? 650 LEU A C 1 ATOM 5197 O O . LEU A 1 650 ? 35.621 85.947 -36.143 1.00 17.94 ? 650 LEU A O 1 ATOM 5198 C CB . LEU A 1 650 ? 36.038 85.609 -39.070 1.00 17.60 ? 650 LEU A CB 1 ATOM 5199 C CG . LEU A 1 650 ? 34.577 85.910 -39.400 1.00 17.39 ? 650 LEU A CG 1 ATOM 5200 C CD1 . LEU A 1 650 ? 34.496 87.190 -40.274 1.00 18.22 ? 650 LEU A CD1 1 ATOM 5201 C CD2 . LEU A 1 650 ? 34.010 84.751 -40.209 1.00 20.64 ? 650 LEU A CD2 1 ATOM 5202 N N . LEU A 1 651 ? 35.626 88.122 -36.669 1.00 17.08 ? 651 LEU A N 1 ATOM 5203 C CA . LEU A 1 651 ? 34.816 88.560 -35.529 1.00 17.65 ? 651 LEU A CA 1 ATOM 5204 C C . LEU A 1 651 ? 33.388 88.766 -36.003 1.00 19.72 ? 651 LEU A C 1 ATOM 5205 O O . LEU A 1 651 ? 33.135 89.577 -36.896 1.00 20.63 ? 651 LEU A O 1 ATOM 5206 C CB . LEU A 1 651 ? 35.377 89.864 -34.961 1.00 21.61 ? 651 LEU A CB 1 ATOM 5207 C CG . LEU A 1 651 ? 35.141 90.296 -33.500 1.00 27.38 ? 651 LEU A CG 1 ATOM 5208 C CD1 . LEU A 1 651 ? 34.047 91.346 -33.429 1.00 30.88 ? 651 LEU A CD1 1 ATOM 5209 C CD2 . LEU A 1 651 ? 34.905 89.096 -32.604 1.00 26.58 ? 651 LEU A CD2 1 ATOM 5210 N N . LEU A 1 652 ? 32.451 88.011 -35.441 1.00 20.29 ? 652 LEU A N 1 ATOM 5211 C CA . LEU A 1 652 ? 31.073 88.100 -35.828 1.00 20.44 ? 652 LEU A CA 1 ATOM 5212 C C . LEU A 1 652 ? 30.267 88.816 -34.769 1.00 22.91 ? 652 LEU A C 1 ATOM 5213 O O . LEU A 1 652 ? 30.108 88.337 -33.632 1.00 22.06 ? 652 LEU A O 1 ATOM 5214 C CB . LEU A 1 652 ? 30.500 86.696 -36.092 1.00 19.27 ? 652 LEU A CB 1 ATOM 5215 C CG . LEU A 1 652 ? 31.244 85.922 -37.177 1.00 19.43 ? 652 LEU A CG 1 ATOM 5216 C CD1 . LEU A 1 652 ? 30.718 84.472 -37.303 1.00 19.80 ? 652 LEU A CD1 1 ATOM 5217 C CD2 . LEU A 1 652 ? 31.127 86.677 -38.523 1.00 20.75 ? 652 LEU A CD2 1 ATOM 5218 N N . ARG A 1 653 ? 29.752 89.983 -35.134 1.00 22.06 ? 653 ARG A N 1 ATOM 5219 C CA . ARG A 1 653 ? 28.939 90.784 -34.249 1.00 27.06 ? 653 ARG A CA 1 ATOM 5220 C C . ARG A 1 653 ? 28.455 91.973 -35.062 1.00 27.07 ? 653 ARG A C 1 ATOM 5221 O O . ARG A 1 653 ? 29.119 92.401 -36.001 1.00 26.44 ? 653 ARG A O 1 ATOM 5222 C CB . ARG A 1 653 ? 29.749 91.292 -33.060 1.00 28.65 ? 653 ARG A CB 1 ATOM 5223 C CG . ARG A 1 653 ? 30.903 92.172 -33.436 1.00 32.34 ? 653 ARG A CG 1 ATOM 5224 C CD . ARG A 1 653 ? 30.799 93.488 -32.699 1.00 38.63 ? 653 ARG A CD 1 ATOM 5225 N NE . ARG A 1 653 ? 31.097 93.395 -31.277 1.00 39.51 ? 653 ARG A NE 1 ATOM 5226 C CZ . ARG A 1 653 ? 30.780 94.325 -30.380 1.00 40.82 ? 653 ARG A CZ 1 ATOM 5227 N NH1 . ARG A 1 653 ? 30.141 95.427 -30.750 1.00 44.47 ? 653 ARG A NH1 1 ATOM 5228 N NH2 . ARG A 1 653 ? 31.111 94.173 -29.112 1.00 43.84 ? 653 ARG A NH2 1 ATOM 5229 N N . LYS A 1 654 ? 27.289 92.486 -34.717 1.00 29.36 ? 654 LYS A N 1 ATOM 5230 C CA . LYS A 1 654 ? 26.816 93.664 -35.415 1.00 32.46 ? 654 LYS A CA 1 ATOM 5231 C C . LYS A 1 654 ? 27.534 94.832 -34.730 1.00 33.24 ? 654 LYS A C 1 ATOM 5232 O O . LYS A 1 654 ? 27.924 94.736 -33.571 1.00 34.33 ? 654 LYS A O 1 ATOM 5233 C CB . LYS A 1 654 ? 25.298 93.763 -35.293 1.00 34.00 ? 654 LYS A CB 1 ATOM 5234 C CG . LYS A 1 654 ? 24.594 92.643 -36.062 1.00 38.94 ? 654 LYS A CG 1 ATOM 5235 C CD . LYS A 1 654 ? 23.188 93.025 -36.491 1.00 43.83 ? 654 LYS A CD 1 ATOM 5236 C CE . LYS A 1 654 ? 23.215 94.183 -37.482 1.00 47.00 ? 654 LYS A CE 1 ATOM 5237 N NZ . LYS A 1 654 ? 21.841 94.555 -37.936 1.00 49.82 ? 654 LYS A NZ 1 ATOM 5238 N N . ASN A 1 655 ? 27.751 95.927 -35.435 1.00 35.76 ? 655 ASN A N 1 ATOM 5239 C CA . ASN A 1 655 ? 28.411 97.056 -34.784 1.00 35.09 ? 655 ASN A CA 1 ATOM 5240 C C . ASN A 1 655 ? 29.830 96.734 -34.314 1.00 32.90 ? 655 ASN A C 1 ATOM 5241 O O . ASN A 1 655 ? 30.178 96.960 -33.156 1.00 33.11 ? 655 ASN A O 1 ATOM 5242 C CB . ASN A 1 655 ? 27.582 97.500 -33.577 1.00 39.84 ? 655 ASN A CB 1 ATOM 5243 C CG . ASN A 1 655 ? 27.900 98.915 -33.140 1.00 46.16 ? 655 ASN A CG 1 ATOM 5244 O OD1 . ASN A 1 655 ? 28.430 99.142 -32.037 1.00 47.41 ? 655 ASN A OD1 1 ATOM 5245 N ND2 . ASN A 1 655 ? 27.575 99.891 -34.004 1.00 48.71 ? 655 ASN A ND2 1 ATOM 5246 N N . PRO A 1 656 ? 30.674 96.204 -35.210 1.00 28.29 ? 656 PRO A N 1 ATOM 5247 C CA . PRO A 1 656 ? 32.040 95.887 -34.788 1.00 26.58 ? 656 PRO A CA 1 ATOM 5248 C C . PRO A 1 656 ? 32.914 97.134 -34.782 1.00 25.68 ? 656 PRO A C 1 ATOM 5249 O O . PRO A 1 656 ? 32.562 98.164 -35.370 1.00 25.25 ? 656 PRO A O 1 ATOM 5250 C CB . PRO A 1 656 ? 32.511 94.917 -35.859 1.00 26.09 ? 656 PRO A CB 1 ATOM 5251 C CG . PRO A 1 656 ? 31.806 95.471 -37.117 1.00 25.59 ? 656 PRO A CG 1 ATOM 5252 C CD . PRO A 1 656 ? 30.423 95.787 -36.608 1.00 27.54 ? 656 PRO A CD 1 ATOM 5253 N N . THR A 1 657 ? 34.042 97.019 -34.094 1.00 25.15 ? 657 THR A N 1 ATOM 5254 C CA . THR A 1 657 ? 35.048 98.061 -34.073 1.00 24.61 ? 657 THR A CA 1 ATOM 5255 C C . THR A 1 657 ? 36.328 97.315 -34.428 1.00 23.45 ? 657 THR A C 1 ATOM 5256 O O . THR A 1 657 ? 36.398 96.072 -34.304 1.00 24.20 ? 657 THR A O 1 ATOM 5257 C CB . THR A 1 657 ? 35.162 98.728 -32.707 1.00 26.79 ? 657 THR A CB 1 ATOM 5258 O OG1 . THR A 1 657 ? 35.254 97.727 -31.689 1.00 27.41 ? 657 THR A OG1 1 ATOM 5259 C CG2 . THR A 1 657 ? 33.930 99.602 -32.457 1.00 26.10 ? 657 THR A CG2 1 ATOM 5260 N N . SER A 1 658 ? 37.336 98.063 -34.866 1.00 22.59 ? 658 SER A N 1 ATOM 5261 C CA . SER A 1 658 ? 38.605 97.510 -35.331 1.00 22.38 ? 658 SER A CA 1 ATOM 5262 C C . SER A 1 658 ? 39.338 96.686 -34.264 1.00 22.62 ? 658 SER A C 1 ATOM 5263 O O . SER A 1 658 ? 39.097 96.854 -33.068 1.00 24.54 ? 658 SER A O 1 ATOM 5264 C CB . SER A 1 658 ? 39.496 98.645 -35.797 1.00 24.23 ? 658 SER A CB 1 ATOM 5265 O OG . SER A 1 658 ? 39.829 99.454 -34.668 1.00 27.52 ? 658 SER A OG 1 ATOM 5266 N N . LEU A 1 659 ? 40.196 95.785 -34.728 1.00 23.12 ? 659 LEU A N 1 ATOM 5267 C CA . LEU A 1 659 ? 40.976 94.897 -33.837 1.00 24.12 ? 659 LEU A CA 1 ATOM 5268 C C . LEU A 1 659 ? 42.382 94.825 -34.388 1.00 24.57 ? 659 LEU A C 1 ATOM 5269 O O . LEU A 1 659 ? 42.727 93.896 -35.121 1.00 25.41 ? 659 LEU A O 1 ATOM 5270 C CB . LEU A 1 659 ? 40.363 93.476 -33.822 1.00 24.60 ? 659 LEU A CB 1 ATOM 5271 C CG . LEU A 1 659 ? 39.018 93.336 -33.102 1.00 26.06 ? 659 LEU A CG 1 ATOM 5272 C CD1 . LEU A 1 659 ? 38.467 91.904 -33.258 1.00 26.63 ? 659 LEU A CD1 1 ATOM 5273 C CD2 . LEU A 1 659 ? 39.189 93.711 -31.644 1.00 27.67 ? 659 LEU A CD2 1 ATOM 5274 N N . PRO A 1 660 ? 43.207 95.839 -34.084 1.00 24.54 ? 660 PRO A N 1 ATOM 5275 C CA . PRO A 1 660 ? 44.586 95.867 -34.571 1.00 23.86 ? 660 PRO A CA 1 ATOM 5276 C C . PRO A 1 660 ? 45.379 94.769 -33.860 1.00 23.49 ? 660 PRO A C 1 ATOM 5277 O O . PRO A 1 660 ? 45.089 94.451 -32.721 1.00 24.37 ? 660 PRO A O 1 ATOM 5278 C CB . PRO A 1 660 ? 45.052 97.280 -34.209 1.00 23.84 ? 660 PRO A CB 1 ATOM 5279 C CG . PRO A 1 660 ? 44.286 97.599 -32.981 1.00 28.05 ? 660 PRO A CG 1 ATOM 5280 C CD . PRO A 1 660 ? 42.889 97.037 -33.292 1.00 24.45 ? 660 PRO A CD 1 ATOM 5281 N N . LEU A 1 661 ? 46.357 94.213 -34.556 1.00 26.39 ? 661 LEU A N 1 ATOM 5282 C CA . LEU A 1 661 ? 47.154 93.111 -33.982 1.00 27.20 ? 661 LEU A CA 1 ATOM 5283 C C . LEU A 1 661 ? 48.681 93.313 -34.106 1.00 28.10 ? 661 LEU A C 1 ATOM 5284 O O . LEU A 1 661 ? 49.416 92.344 -34.304 1.00 25.39 ? 661 LEU A O 1 ATOM 5285 C CB . LEU A 1 661 ? 46.763 91.813 -34.684 1.00 26.62 ? 661 LEU A CB 1 ATOM 5286 C CG . LEU A 1 661 ? 45.319 91.339 -34.497 1.00 23.15 ? 661 LEU A CG 1 ATOM 5287 C CD1 . LEU A 1 661 ? 45.089 90.042 -35.312 1.00 24.12 ? 661 LEU A CD1 1 ATOM 5288 C CD2 . LEU A 1 661 ? 45.055 91.103 -33.012 1.00 26.74 ? 661 LEU A CD2 1 ATOM 5289 N N . GLY A 1 662 ? 49.157 94.558 -34.007 1.00 30.32 ? 662 GLY A N 1 ATOM 5290 C CA . GLY A 1 662 ? 50.597 94.822 -34.125 1.00 28.60 ? 662 GLY A CA 1 ATOM 5291 C C . GLY A 1 662 ? 51.188 94.283 -35.419 1.00 29.98 ? 662 GLY A C 1 ATOM 5292 O O . GLY A 1 662 ? 50.681 94.542 -36.514 1.00 30.83 ? 662 GLY A O 1 ATOM 5293 N N . GLN A 1 663 ? 52.244 93.477 -35.316 1.00 28.89 ? 663 GLN A N 1 ATOM 5294 C CA . GLN A 1 663 ? 52.856 92.944 -36.520 1.00 28.54 ? 663 GLN A CA 1 ATOM 5295 C C . GLN A 1 663 ? 52.161 91.734 -37.164 1.00 25.10 ? 663 GLN A C 1 ATOM 5296 O O . GLN A 1 663 ? 52.572 91.291 -38.226 1.00 28.72 ? 663 GLN A O 1 ATOM 5297 C CB . GLN A 1 663 ? 54.309 92.552 -36.247 1.00 32.38 ? 663 GLN A CB 1 ATOM 5298 C CG . GLN A 1 663 ? 55.110 93.512 -35.355 1.00 35.94 ? 663 GLN A CG 1 ATOM 5299 C CD . GLN A 1 663 ? 56.438 92.880 -34.960 1.00 37.54 ? 663 GLN A CD 1 ATOM 5300 O OE1 . GLN A 1 663 ? 57.303 92.649 -35.827 1.00 34.75 ? 663 GLN A OE1 1 ATOM 5301 N NE2 . GLN A 1 663 ? 56.598 92.565 -33.665 1.00 37.87 ? 663 GLN A NE2 1 ATOM 5302 N N . TYR A 1 664 ? 51.113 91.203 -36.542 1.00 26.54 ? 664 TYR A N 1 ATOM 5303 C CA . TYR A 1 664 ? 50.437 90.032 -37.113 1.00 25.83 ? 664 TYR A CA 1 ATOM 5304 C C . TYR A 1 664 ? 50.148 90.348 -38.573 1.00 23.70 ? 664 TYR A C 1 ATOM 5305 O O . TYR A 1 664 ? 49.468 91.329 -38.854 1.00 25.50 ? 664 TYR A O 1 ATOM 5306 C CB . TYR A 1 664 ? 49.160 89.777 -36.324 1.00 23.39 ? 664 TYR A CB 1 ATOM 5307 C CG . TYR A 1 664 ? 48.574 88.432 -36.591 1.00 20.76 ? 664 TYR A CG 1 ATOM 5308 C CD1 . TYR A 1 664 ? 49.114 87.289 -35.985 1.00 18.94 ? 664 TYR A CD1 1 ATOM 5309 C CD2 . TYR A 1 664 ? 47.477 88.284 -37.451 1.00 18.85 ? 664 TYR A CD2 1 ATOM 5310 C CE1 . TYR A 1 664 ? 48.562 86.042 -36.222 1.00 20.00 ? 664 TYR A CE1 1 ATOM 5311 C CE2 . TYR A 1 664 ? 46.923 87.041 -37.711 1.00 18.67 ? 664 TYR A CE2 1 ATOM 5312 C CZ . TYR A 1 664 ? 47.477 85.916 -37.078 1.00 18.42 ? 664 TYR A CZ 1 ATOM 5313 O OH . TYR A 1 664 ? 46.900 84.710 -37.297 1.00 18.76 ? 664 TYR A OH 1 ATOM 5314 N N . PRO A 1 665 ? 50.606 89.500 -39.511 1.00 26.90 ? 665 PRO A N 1 ATOM 5315 C CA . PRO A 1 665 ? 50.407 89.747 -40.947 1.00 27.63 ? 665 PRO A CA 1 ATOM 5316 C C . PRO A 1 665 ? 49.066 89.612 -41.633 1.00 29.32 ? 665 PRO A C 1 ATOM 5317 O O . PRO A 1 665 ? 48.975 89.866 -42.832 1.00 32.69 ? 665 PRO A O 1 ATOM 5318 C CB . PRO A 1 665 ? 51.445 88.832 -41.594 1.00 27.95 ? 665 PRO A CB 1 ATOM 5319 C CG . PRO A 1 665 ? 51.388 87.628 -40.683 1.00 27.53 ? 665 PRO A CG 1 ATOM 5320 C CD . PRO A 1 665 ? 51.370 88.254 -39.303 1.00 25.34 ? 665 PRO A CD 1 ATOM 5321 N N . GLU A 1 666 ? 48.027 89.230 -40.912 1.00 27.49 ? 666 GLU A N 1 ATOM 5322 C CA . GLU A 1 666 ? 46.724 89.058 -41.551 1.00 25.73 ? 666 GLU A CA 1 ATOM 5323 C C . GLU A 1 666 ? 45.707 89.931 -40.821 1.00 24.67 ? 666 GLU A C 1 ATOM 5324 O O . GLU A 1 666 ? 45.571 89.842 -39.604 1.00 24.32 ? 666 GLU A O 1 ATOM 5325 C CB . GLU A 1 666 ? 46.328 87.585 -41.468 1.00 30.13 ? 666 GLU A CB 1 ATOM 5326 C CG . GLU A 1 666 ? 44.895 87.346 -41.797 1.00 35.96 ? 666 GLU A CG 1 ATOM 5327 C CD . GLU A 1 666 ? 44.689 86.769 -43.182 1.00 39.10 ? 666 GLU A CD 1 ATOM 5328 O OE1 . GLU A 1 666 ? 45.657 86.815 -44.003 1.00 40.57 ? 666 GLU A OE1 1 ATOM 5329 O OE2 . GLU A 1 666 ? 43.554 86.280 -43.428 1.00 37.84 ? 666 GLU A OE2 1 ATOM 5330 N N . ASP A 1 667 ? 44.995 90.804 -41.549 1.00 23.02 ? 667 ASP A N 1 ATOM 5331 C CA . ASP A 1 667 ? 44.003 91.668 -40.913 1.00 22.98 ? 667 ASP A CA 1 ATOM 5332 C C . ASP A 1 667 ? 42.753 90.895 -40.454 1.00 18.13 ? 667 ASP A C 1 ATOM 5333 O O . ASP A 1 667 ? 42.275 90.008 -41.161 1.00 18.94 ? 667 ASP A O 1 ATOM 5334 C CB . ASP A 1 667 ? 43.504 92.761 -41.896 1.00 26.13 ? 667 ASP A CB 1 ATOM 5335 C CG . ASP A 1 667 ? 44.593 93.746 -42.292 1.00 31.34 ? 667 ASP A CG 1 ATOM 5336 O OD1 . ASP A 1 667 ? 45.539 93.965 -41.499 1.00 33.74 ? 667 ASP A OD1 1 ATOM 5337 O OD2 . ASP A 1 667 ? 44.491 94.328 -43.395 1.00 33.71 ? 667 ASP A OD2 1 ATOM 5338 N N . VAL A 1 668 ? 42.238 91.248 -39.291 1.00 20.10 ? 668 VAL A N 1 ATOM 5339 C CA . VAL A 1 668 ? 41.002 90.643 -38.795 1.00 19.05 ? 668 VAL A CA 1 ATOM 5340 C C . VAL A 1 668 ? 39.839 91.033 -39.733 1.00 19.75 ? 668 VAL A C 1 ATOM 5341 O O . VAL A 1 668 ? 39.768 92.186 -40.200 1.00 22.51 ? 668 VAL A O 1 ATOM 5342 C CB . VAL A 1 668 ? 40.653 91.148 -37.361 1.00 18.75 ? 668 VAL A CB 1 ATOM 5343 C CG1 . VAL A 1 668 ? 39.303 90.557 -36.890 1.00 19.34 ? 668 VAL A CG1 1 ATOM 5344 C CG2 . VAL A 1 668 ? 41.761 90.701 -36.390 1.00 20.47 ? 668 VAL A CG2 1 ATOM 5345 N N . LYS A 1 669 ? 38.953 90.076 -39.993 1.00 17.90 ? 669 LYS A N 1 ATOM 5346 C CA . LYS A 1 669 ? 37.749 90.242 -40.827 1.00 18.18 ? 669 LYS A CA 1 ATOM 5347 C C . LYS A 1 669 ? 36.528 90.344 -39.916 1.00 20.05 ? 669 LYS A C 1 ATOM 5348 O O . LYS A 1 669 ? 36.508 89.761 -38.806 1.00 19.35 ? 669 LYS A O 1 ATOM 5349 C CB . LYS A 1 669 ? 37.590 89.061 -41.771 1.00 22.36 ? 669 LYS A CB 1 ATOM 5350 C CG . LYS A 1 669 ? 38.263 89.223 -43.125 1.00 32.86 ? 669 LYS A CG 1 ATOM 5351 C CD . LYS A 1 669 ? 39.764 89.059 -43.066 1.00 36.33 ? 669 LYS A CD 1 ATOM 5352 C CE . LYS A 1 669 ? 40.443 89.749 -44.267 1.00 36.63 ? 669 LYS A CE 1 ATOM 5353 N NZ . LYS A 1 669 ? 41.928 89.736 -44.096 1.00 34.94 ? 669 LYS A NZ 1 ATOM 5354 N N . PHE A 1 670 ? 35.490 91.042 -40.380 1.00 18.41 ? 670 PHE A N 1 ATOM 5355 C CA . PHE A 1 670 ? 34.292 91.252 -39.579 1.00 18.32 ? 670 PHE A CA 1 ATOM 5356 C C . PHE A 1 670 ? 33.053 90.825 -40.334 1.00 20.24 ? 670 PHE A C 1 ATOM 5357 O O . PHE A 1 670 ? 33.072 90.754 -41.543 1.00 20.19 ? 670 PHE A O 1 ATOM 5358 C CB . PHE A 1 670 ? 34.143 92.715 -39.157 1.00 19.00 ? 670 PHE A CB 1 ATOM 5359 C CG . PHE A 1 670 ? 35.290 93.212 -38.346 1.00 18.73 ? 670 PHE A CG 1 ATOM 5360 C CD1 . PHE A 1 670 ? 36.444 93.669 -38.987 1.00 20.85 ? 670 PHE A CD1 1 ATOM 5361 C CD2 . PHE A 1 670 ? 35.264 93.143 -36.957 1.00 20.80 ? 670 PHE A CD2 1 ATOM 5362 C CE1 . PHE A 1 670 ? 37.568 94.049 -38.234 1.00 22.47 ? 670 PHE A CE1 1 ATOM 5363 C CE2 . PHE A 1 670 ? 36.371 93.517 -36.206 1.00 24.46 ? 670 PHE A CE2 1 ATOM 5364 C CZ . PHE A 1 670 ? 37.532 93.975 -36.863 1.00 22.19 ? 670 PHE A CZ 1 ATOM 5365 N N . GLY A 1 671 ? 31.971 90.533 -39.608 1.00 20.83 ? 671 GLY A N 1 ATOM 5366 C CA . GLY A 1 671 ? 30.739 90.112 -40.269 1.00 19.57 ? 671 GLY A CA 1 ATOM 5367 C C . GLY A 1 671 ? 29.604 90.058 -39.265 1.00 20.50 ? 671 GLY A C 1 ATOM 5368 O O . GLY A 1 671 ? 29.823 90.049 -38.051 1.00 19.57 ? 671 GLY A O 1 ATOM 5369 N N . ASP A 1 672 ? 28.375 90.047 -39.755 1.00 19.89 ? 672 ASP A N 1 ATOM 5370 C CA . ASP A 1 672 ? 27.237 89.927 -38.870 1.00 21.66 ? 672 ASP A CA 1 ATOM 5371 C C . ASP A 1 672 ? 27.190 88.460 -38.418 1.00 21.31 ? 672 ASP A C 1 ATOM 5372 O O . ASP A 1 672 ? 27.691 87.585 -39.125 1.00 19.99 ? 672 ASP A O 1 ATOM 5373 C CB . ASP A 1 672 ? 25.935 90.214 -39.638 1.00 24.02 ? 672 ASP A CB 1 ATOM 5374 C CG . ASP A 1 672 ? 25.644 91.698 -39.796 1.00 28.41 ? 672 ASP A CG 1 ATOM 5375 O OD1 . ASP A 1 672 ? 26.454 92.541 -39.379 1.00 29.58 ? 672 ASP A OD1 1 ATOM 5376 O OD2 . ASP A 1 672 ? 24.565 92.005 -40.347 1.00 33.83 ? 672 ASP A OD2 1 ATOM 5377 N N . PRO A 1 673 ? 26.602 88.189 -37.239 1.00 22.19 ? 673 PRO A N 1 ATOM 5378 C CA . PRO A 1 673 ? 26.505 86.802 -36.754 1.00 23.63 ? 673 PRO A CA 1 ATOM 5379 C C . PRO A 1 673 ? 25.910 85.915 -37.851 1.00 22.74 ? 673 PRO A C 1 ATOM 5380 O O . PRO A 1 673 ? 24.991 86.328 -38.588 1.00 24.71 ? 673 PRO A O 1 ATOM 5381 C CB . PRO A 1 673 ? 25.576 86.935 -35.555 1.00 24.54 ? 673 PRO A CB 1 ATOM 5382 C CG . PRO A 1 673 ? 25.940 88.261 -34.987 1.00 26.73 ? 673 PRO A CG 1 ATOM 5383 C CD . PRO A 1 673 ? 26.112 89.140 -36.218 1.00 23.78 ? 673 PRO A CD 1 ATOM 5384 N N . ARG A 1 674 ? 26.417 84.694 -37.967 1.00 21.13 ? 674 ARG A N 1 ATOM 5385 C CA . ARG A 1 674 ? 25.939 83.765 -38.981 1.00 22.23 ? 674 ARG A CA 1 ATOM 5386 C C . ARG A 1 674 ? 26.406 82.359 -38.650 1.00 23.52 ? 674 ARG A C 1 ATOM 5387 O O . ARG A 1 674 ? 27.331 82.180 -37.856 1.00 22.74 ? 674 ARG A O 1 ATOM 5388 C CB . ARG A 1 674 ? 26.482 84.161 -40.365 1.00 22.52 ? 674 ARG A CB 1 ATOM 5389 C CG . ARG A 1 674 ? 27.989 84.079 -40.534 1.00 26.04 ? 674 ARG A CG 1 ATOM 5390 C CD . ARG A 1 674 ? 28.313 84.142 -42.034 1.00 28.46 ? 674 ARG A CD 1 ATOM 5391 N NE . ARG A 1 674 ? 29.695 83.834 -42.367 1.00 30.21 ? 674 ARG A NE 1 ATOM 5392 C CZ . ARG A 1 674 ? 30.672 84.730 -42.469 1.00 29.88 ? 674 ARG A CZ 1 ATOM 5393 N NH1 . ARG A 1 674 ? 30.438 86.030 -42.258 1.00 33.55 ? 674 ARG A NH1 1 ATOM 5394 N NH2 . ARG A 1 674 ? 31.883 84.322 -42.831 1.00 29.52 ? 674 ARG A NH2 1 ATOM 5395 N N . GLU A 1 675 ? 25.757 81.355 -39.223 1.00 21.93 ? 675 GLU A N 1 ATOM 5396 C CA . GLU A 1 675 ? 26.194 79.996 -38.986 1.00 22.82 ? 675 GLU A CA 1 ATOM 5397 C C . GLU A 1 675 ? 27.518 79.776 -39.697 1.00 24.26 ? 675 GLU A C 1 ATOM 5398 O O . GLU A 1 675 ? 27.787 80.350 -40.770 1.00 25.72 ? 675 GLU A O 1 ATOM 5399 C CB . GLU A 1 675 ? 25.125 79.003 -39.472 1.00 25.14 ? 675 GLU A CB 1 ATOM 5400 C CG . GLU A 1 675 ? 23.843 79.204 -38.707 1.00 29.18 ? 675 GLU A CG 1 ATOM 5401 C CD . GLU A 1 675 ? 22.959 77.987 -38.702 1.00 33.93 ? 675 GLU A CD 1 ATOM 5402 O OE1 . GLU A 1 675 ? 23.040 77.224 -39.694 1.00 36.26 ? 675 GLU A OE1 1 ATOM 5403 O OE2 . GLU A 1 675 ? 22.183 77.809 -37.713 1.00 37.93 ? 675 GLU A OE2 1 ATOM 5404 N N . ILE A 1 676 ? 28.383 78.951 -39.119 1.00 22.53 ? 676 ILE A N 1 ATOM 5405 C CA . ILE A 1 676 ? 29.661 78.713 -39.749 1.00 23.50 ? 676 ILE A CA 1 ATOM 5406 C C . ILE A 1 676 ? 30.046 77.248 -39.632 1.00 22.40 ? 676 ILE A C 1 ATOM 5407 O O . ILE A 1 676 ? 29.573 76.551 -38.744 1.00 21.53 ? 676 ILE A O 1 ATOM 5408 C CB . ILE A 1 676 ? 30.755 79.554 -39.107 1.00 28.24 ? 676 ILE A CB 1 ATOM 5409 C CG1 . ILE A 1 676 ? 31.234 78.885 -37.836 1.00 28.74 ? 676 ILE A CG1 1 ATOM 5410 C CG2 . ILE A 1 676 ? 30.228 80.900 -38.705 1.00 31.96 ? 676 ILE A CG2 1 ATOM 5411 C CD1 . ILE A 1 676 ? 32.472 79.504 -37.247 1.00 32.61 ? 676 ILE A CD1 1 ATOM 5412 N N . SER A 1 677 ? 30.908 76.804 -40.535 1.00 22.10 ? 677 SER A N 1 ATOM 5413 C CA . SER A 1 677 ? 31.390 75.429 -40.591 1.00 22.36 ? 677 SER A CA 1 ATOM 5414 C C . SER A 1 677 ? 32.921 75.418 -40.670 1.00 22.35 ? 677 SER A C 1 ATOM 5415 O O . SER A 1 677 ? 33.515 76.217 -41.398 1.00 22.91 ? 677 SER A O 1 ATOM 5416 C CB A SER A 1 677 ? 30.808 74.737 -41.832 0.50 23.56 ? 677 SER A CB 1 ATOM 5417 C CB B SER A 1 677 ? 30.769 74.555 -41.606 0.50 23.72 ? 677 SER A CB 1 ATOM 5418 O OG A SER A 1 677 ? 31.277 73.414 -41.944 0.50 25.41 ? 677 SER A OG 1 ATOM 5419 O OG B SER A 1 677 ? 29.425 74.241 -41.297 0.50 26.43 ? 677 SER A OG 1 ATOM 5420 N N . LEU A 1 678 ? 33.565 74.512 -39.934 1.00 20.81 ? 678 LEU A N 1 ATOM 5421 C CA . LEU A 1 678 ? 35.009 74.426 -39.939 1.00 21.33 ? 678 LEU A CA 1 ATOM 5422 C C . LEU A 1 678 ? 35.476 72.999 -40.011 1.00 20.49 ? 678 LEU A C 1 ATOM 5423 O O . LEU A 1 678 ? 34.796 72.087 -39.504 1.00 20.35 ? 678 LEU A O 1 ATOM 5424 C CB . LEU A 1 678 ? 35.599 74.983 -38.638 1.00 22.06 ? 678 LEU A CB 1 ATOM 5425 C CG . LEU A 1 678 ? 35.653 76.473 -38.379 1.00 23.47 ? 678 LEU A CG 1 ATOM 5426 C CD1 . LEU A 1 678 ? 36.146 76.721 -36.949 1.00 22.67 ? 678 LEU A CD1 1 ATOM 5427 C CD2 . LEU A 1 678 ? 36.629 77.097 -39.344 1.00 25.93 ? 678 LEU A CD2 1 ATOM 5428 N N . ARG A 1 679 ? 36.629 72.816 -40.631 1.00 20.50 ? 679 ARG A N 1 ATOM 5429 C CA . ARG A 1 679 ? 37.234 71.499 -40.731 1.00 22.70 ? 679 ARG A CA 1 ATOM 5430 C C . ARG A 1 679 ? 38.751 71.655 -40.708 1.00 23.63 ? 679 ARG A C 1 ATOM 5431 O O . ARG A 1 679 ? 39.332 72.424 -41.484 1.00 23.92 ? 679 ARG A O 1 ATOM 5432 C CB . ARG A 1 679 ? 36.793 70.796 -42.024 1.00 25.05 ? 679 ARG A CB 1 ATOM 5433 C CG . ARG A 1 679 ? 37.259 69.348 -42.060 1.00 25.59 ? 679 ARG A CG 1 ATOM 5434 C CD . ARG A 1 679 ? 37.116 68.752 -43.453 1.00 29.31 ? 679 ARG A CD 1 ATOM 5435 N NE . ARG A 1 679 ? 37.498 67.352 -43.409 1.00 35.59 ? 679 ARG A NE 1 ATOM 5436 C CZ . ARG A 1 679 ? 37.660 66.587 -44.478 1.00 39.26 ? 679 ARG A CZ 1 ATOM 5437 N NH1 . ARG A 1 679 ? 37.474 67.095 -45.694 1.00 41.20 ? 679 ARG A NH1 1 ATOM 5438 N NH2 . ARG A 1 679 ? 38.001 65.315 -44.322 1.00 41.69 ? 679 ARG A NH2 1 ATOM 5439 N N . VAL A 1 680 ? 39.409 70.974 -39.781 1.00 22.44 ? 680 VAL A N 1 ATOM 5440 C CA . VAL A 1 680 ? 40.842 71.005 -39.723 1.00 20.69 ? 680 VAL A CA 1 ATOM 5441 C C . VAL A 1 680 ? 41.368 69.644 -40.189 1.00 23.95 ? 680 VAL A C 1 ATOM 5442 O O . VAL A 1 680 ? 40.836 68.582 -39.794 1.00 23.81 ? 680 VAL A O 1 ATOM 5443 C CB . VAL A 1 680 ? 41.316 71.299 -38.280 1.00 19.22 ? 680 VAL A CB 1 ATOM 5444 C CG1 . VAL A 1 680 ? 42.808 71.129 -38.183 1.00 22.31 ? 680 VAL A CG1 1 ATOM 5445 C CG2 . VAL A 1 680 ? 40.896 72.729 -37.876 1.00 19.62 ? 680 VAL A CG2 1 ATOM 5446 N N . GLY A 1 681 ? 42.381 69.683 -41.054 1.00 25.19 ? 681 GLY A N 1 ATOM 5447 C CA . GLY A 1 681 ? 42.948 68.448 -41.576 1.00 29.66 ? 681 GLY A CA 1 ATOM 5448 C C . GLY A 1 681 ? 41.891 67.641 -42.327 1.00 31.73 ? 681 GLY A C 1 ATOM 5449 O O . GLY A 1 681 ? 41.067 68.209 -43.063 1.00 32.95 ? 681 GLY A O 1 ATOM 5450 N N . ASN A 1 682 ? 41.927 66.317 -42.137 1.00 35.97 ? 682 ASN A N 1 ATOM 5451 C CA . ASN A 1 682 ? 40.968 65.393 -42.753 1.00 37.24 ? 682 ASN A CA 1 ATOM 5452 C C . ASN A 1 682 ? 39.993 65.000 -41.654 1.00 36.89 ? 682 ASN A C 1 ATOM 5453 O O . ASN A 1 682 ? 39.199 64.062 -41.800 1.00 38.54 ? 682 ASN A O 1 ATOM 5454 C CB . ASN A 1 682 ? 41.658 64.120 -43.243 1.00 41.14 ? 682 ASN A CB 1 ATOM 5455 C CG . ASN A 1 682 ? 42.906 64.404 -44.035 1.00 43.94 ? 682 ASN A CG 1 ATOM 5456 O OD1 . ASN A 1 682 ? 42.865 65.083 -45.064 1.00 46.99 ? 682 ASN A OD1 1 ATOM 5457 N ND2 . ASN A 1 682 ? 44.037 63.882 -43.561 1.00 46.37 ? 682 ASN A ND2 1 ATOM 5458 N N . GLY A 1 683 ? 40.053 65.736 -40.552 1.00 34.57 ? 683 GLY A N 1 ATOM 5459 C CA . GLY A 1 683 ? 39.206 65.451 -39.418 1.00 32.48 ? 683 GLY A CA 1 ATOM 5460 C C . GLY A 1 683 ? 37.741 65.750 -39.627 1.00 29.96 ? 683 GLY A C 1 ATOM 5461 O O . GLY A 1 683 ? 37.288 65.954 -40.753 1.00 29.39 ? 683 GLY A O 1 ATOM 5462 N N . PRO A 1 684 ? 36.967 65.808 -38.535 1.00 26.50 ? 684 PRO A N 1 ATOM 5463 C CA . PRO A 1 684 ? 35.531 66.086 -38.655 1.00 24.29 ? 684 PRO A CA 1 ATOM 5464 C C . PRO A 1 684 ? 35.195 67.522 -39.053 1.00 22.90 ? 684 PRO A C 1 ATOM 5465 O O . PRO A 1 684 ? 35.998 68.409 -38.878 1.00 22.11 ? 684 PRO A O 1 ATOM 5466 C CB . PRO A 1 684 ? 34.982 65.731 -37.272 1.00 24.57 ? 684 PRO A CB 1 ATOM 5467 C CG . PRO A 1 684 ? 36.189 66.063 -36.331 1.00 24.80 ? 684 PRO A CG 1 ATOM 5468 C CD . PRO A 1 684 ? 37.384 65.609 -37.134 1.00 27.37 ? 684 PRO A CD 1 ATOM 5469 N N . THR A 1 685 ? 34.014 67.714 -39.617 1.00 21.56 ? 685 THR A N 1 ATOM 5470 C CA . THR A 1 685 ? 33.556 69.043 -39.988 1.00 21.25 ? 685 THR A CA 1 ATOM 5471 C C . THR A 1 685 ? 32.507 69.403 -38.946 1.00 22.36 ? 685 THR A C 1 ATOM 5472 O O . THR A 1 685 ? 31.543 68.666 -38.715 1.00 21.98 ? 685 THR A O 1 ATOM 5473 C CB . THR A 1 685 ? 32.934 69.071 -41.394 1.00 22.64 ? 685 THR A CB 1 ATOM 5474 O OG1 . THR A 1 685 ? 33.956 68.773 -42.348 1.00 23.26 ? 685 THR A OG1 1 ATOM 5475 C CG2 . THR A 1 685 ? 32.334 70.442 -41.678 1.00 21.60 ? 685 THR A CG2 1 ATOM 5476 N N . LEU A 1 686 ? 32.694 70.563 -38.315 1.00 18.89 ? 686 LEU A N 1 ATOM 5477 C CA . LEU A 1 686 ? 31.800 70.996 -37.283 1.00 20.52 ? 686 LEU A CA 1 ATOM 5478 C C . LEU A 1 686 ? 31.026 72.217 -37.724 1.00 18.89 ? 686 LEU A C 1 ATOM 5479 O O . LEU A 1 686 ? 31.616 73.154 -38.259 1.00 21.04 ? 686 LEU A O 1 ATOM 5480 C CB . LEU A 1 686 ? 32.582 71.383 -36.010 1.00 19.53 ? 686 LEU A CB 1 ATOM 5481 C CG . LEU A 1 686 ? 33.557 70.408 -35.336 1.00 26.08 ? 686 LEU A CG 1 ATOM 5482 C CD1 . LEU A 1 686 ? 33.738 70.843 -33.883 1.00 22.31 ? 686 LEU A CD1 1 ATOM 5483 C CD2 . LEU A 1 686 ? 33.126 69.001 -35.435 1.00 21.91 ? 686 LEU A CD2 1 ATOM 5484 N N . ALA A 1 687 ? 29.744 72.213 -37.442 1.00 17.81 ? 687 ALA A N 1 ATOM 5485 C CA . ALA A 1 687 ? 28.876 73.345 -37.740 1.00 17.85 ? 687 ALA A CA 1 ATOM 5486 C C . ALA A 1 687 ? 28.423 74.020 -36.463 1.00 20.16 ? 687 ALA A C 1 ATOM 5487 O O . ALA A 1 687 ? 28.067 73.354 -35.483 1.00 19.91 ? 687 ALA A O 1 ATOM 5488 C CB . ALA A 1 687 ? 27.640 72.868 -38.543 1.00 20.31 ? 687 ALA A CB 1 ATOM 5489 N N . PHE A 1 688 ? 28.404 75.351 -36.484 1.00 17.32 ? 688 PHE A N 1 ATOM 5490 C CA . PHE A 1 688 ? 28.045 76.166 -35.355 1.00 16.67 ? 688 PHE A CA 1 ATOM 5491 C C . PHE A 1 688 ? 26.871 77.080 -35.636 1.00 16.41 ? 688 PHE A C 1 ATOM 5492 O O . PHE A 1 688 ? 26.691 77.544 -36.780 1.00 20.31 ? 688 PHE A O 1 ATOM 5493 C CB . PHE A 1 688 ? 29.230 77.056 -34.944 1.00 16.51 ? 688 PHE A CB 1 ATOM 5494 C CG . PHE A 1 688 ? 30.459 76.292 -34.614 1.00 15.54 ? 688 PHE A CG 1 ATOM 5495 C CD1 . PHE A 1 688 ? 31.288 75.803 -35.590 1.00 15.56 ? 688 PHE A CD1 1 ATOM 5496 C CD2 . PHE A 1 688 ? 30.744 76.017 -33.283 1.00 15.62 ? 688 PHE A CD2 1 ATOM 5497 C CE1 . PHE A 1 688 ? 32.412 75.029 -35.296 1.00 15.73 ? 688 PHE A CE1 1 ATOM 5498 C CE2 . PHE A 1 688 ? 31.852 75.253 -32.953 1.00 14.98 ? 688 PHE A CE2 1 ATOM 5499 C CZ . PHE A 1 688 ? 32.692 74.753 -33.941 1.00 14.69 ? 688 PHE A CZ 1 ATOM 5500 N N . SER A 1 689 ? 26.095 77.356 -34.606 1.00 16.91 ? 689 SER A N 1 ATOM 5501 C CA . SER A 1 689 ? 24.957 78.289 -34.679 1.00 17.07 ? 689 SER A CA 1 ATOM 5502 C C . SER A 1 689 ? 25.507 79.712 -34.755 1.00 19.66 ? 689 SER A C 1 ATOM 5503 O O . SER A 1 689 ? 26.706 79.933 -34.561 1.00 18.67 ? 689 SER A O 1 ATOM 5504 C CB . SER A 1 689 ? 24.081 78.175 -33.438 1.00 20.24 ? 689 SER A CB 1 ATOM 5505 O OG . SER A 1 689 ? 24.722 78.733 -32.317 1.00 21.17 ? 689 SER A OG 1 ATOM 5506 N N . GLU A 1 690 ? 24.630 80.674 -35.031 1.00 21.19 ? 690 GLU A N 1 ATOM 5507 C CA . GLU A 1 690 ? 25.065 82.059 -35.087 1.00 22.48 ? 690 GLU A CA 1 ATOM 5508 C C . GLU A 1 690 ? 25.432 82.565 -33.689 1.00 22.23 ? 690 GLU A C 1 ATOM 5509 O O . GLU A 1 690 ? 25.988 83.663 -33.535 1.00 20.46 ? 690 GLU A O 1 ATOM 5510 C CB . GLU A 1 690 ? 23.970 82.931 -35.727 1.00 25.07 ? 690 GLU A CB 1 ATOM 5511 C CG . GLU A 1 690 ? 22.803 83.252 -34.874 1.00 28.51 ? 690 GLU A CG 1 ATOM 5512 C CD . GLU A 1 690 ? 21.910 84.300 -35.552 1.00 33.96 ? 690 GLU A CD 1 ATOM 5513 O OE1 . GLU A 1 690 ? 21.376 83.993 -36.649 1.00 36.18 ? 690 GLU A OE1 1 ATOM 5514 O OE2 . GLU A 1 690 ? 21.761 85.420 -35.000 1.00 36.61 ? 690 GLU A OE2 1 ATOM 5515 N N . GLN A 1 691 ? 25.134 81.772 -32.660 1.00 20.80 ? 691 GLN A N 1 ATOM 5516 C CA . GLN A 1 691 ? 25.544 82.158 -31.305 1.00 20.40 ? 691 GLN A CA 1 ATOM 5517 C C . GLN A 1 691 ? 26.882 81.495 -30.923 1.00 19.48 ? 691 GLN A C 1 ATOM 5518 O O . GLN A 1 691 ? 27.289 81.579 -29.779 1.00 21.80 ? 691 GLN A O 1 ATOM 5519 C CB . GLN A 1 691 ? 24.510 81.791 -30.240 1.00 23.03 ? 691 GLN A CB 1 ATOM 5520 C CG . GLN A 1 691 ? 23.278 82.600 -30.315 1.00 27.59 ? 691 GLN A CG 1 ATOM 5521 C CD . GLN A 1 691 ? 22.142 81.693 -30.499 1.00 35.63 ? 691 GLN A CD 1 ATOM 5522 O OE1 . GLN A 1 691 ? 21.642 81.081 -29.525 1.00 37.30 ? 691 GLN A OE1 1 ATOM 5523 N NE2 . GLN A 1 691 ? 21.728 81.535 -31.747 1.00 36.14 ? 691 GLN A NE2 1 ATOM 5524 N N . GLY A 1 692 ? 27.541 80.850 -31.873 1.00 18.32 ? 692 GLY A N 1 ATOM 5525 C CA . GLY A 1 692 ? 28.856 80.256 -31.638 1.00 19.19 ? 692 GLY A CA 1 ATOM 5526 C C . GLY A 1 692 ? 28.871 78.901 -30.969 1.00 18.78 ? 692 GLY A C 1 ATOM 5527 O O . GLY A 1 692 ? 29.926 78.467 -30.508 1.00 18.94 ? 692 GLY A O 1 ATOM 5528 N N . LEU A 1 693 ? 27.730 78.224 -30.925 1.00 18.47 ? 693 LEU A N 1 ATOM 5529 C CA . LEU A 1 693 ? 27.637 76.901 -30.281 1.00 18.91 ? 693 LEU A CA 1 ATOM 5530 C C . LEU A 1 693 ? 27.493 75.785 -31.281 1.00 18.10 ? 693 LEU A C 1 ATOM 5531 O O . LEU A 1 693 ? 26.766 75.914 -32.287 1.00 18.12 ? 693 LEU A O 1 ATOM 5532 C CB . LEU A 1 693 ? 26.449 76.888 -29.333 1.00 21.15 ? 693 LEU A CB 1 ATOM 5533 C CG . LEU A 1 693 ? 26.564 77.883 -28.182 1.00 23.99 ? 693 LEU A CG 1 ATOM 5534 C CD1 . LEU A 1 693 ? 25.170 78.387 -27.838 1.00 28.12 ? 693 LEU A CD1 1 ATOM 5535 C CD2 . LEU A 1 693 ? 27.213 77.238 -26.976 1.00 24.36 ? 693 LEU A CD2 1 ATOM 5536 N N . LEU A 1 694 ? 28.161 74.671 -31.025 1.00 15.56 ? 694 LEU A N 1 ATOM 5537 C CA . LEU A 1 694 ? 28.094 73.519 -31.886 1.00 15.44 ? 694 LEU A CA 1 ATOM 5538 C C . LEU A 1 694 ? 26.652 73.121 -32.164 1.00 16.04 ? 694 LEU A C 1 ATOM 5539 O O . LEU A 1 694 ? 25.784 73.138 -31.262 1.00 16.36 ? 694 LEU A O 1 ATOM 5540 C CB . LEU A 1 694 ? 28.827 72.343 -31.212 1.00 16.79 ? 694 LEU A CB 1 ATOM 5541 C CG . LEU A 1 694 ? 28.981 71.120 -32.103 1.00 17.32 ? 694 LEU A CG 1 ATOM 5542 C CD1 . LEU A 1 694 ? 29.933 71.385 -33.235 1.00 17.32 ? 694 LEU A CD1 1 ATOM 5543 C CD2 . LEU A 1 694 ? 29.577 69.972 -31.222 1.00 17.99 ? 694 LEU A CD2 1 ATOM 5544 N N . LYS A 1 695 ? 26.413 72.779 -33.427 1.00 19.10 ? 695 LYS A N 1 ATOM 5545 C CA . LYS A 1 695 ? 25.109 72.360 -33.915 1.00 21.21 ? 695 LYS A CA 1 ATOM 5546 C C . LYS A 1 695 ? 25.179 70.949 -34.488 1.00 19.90 ? 695 LYS A C 1 ATOM 5547 O O . LYS A 1 695 ? 24.235 70.175 -34.331 1.00 22.16 ? 695 LYS A O 1 ATOM 5548 C CB . LYS A 1 695 ? 24.657 73.347 -35.004 1.00 25.20 ? 695 LYS A CB 1 ATOM 5549 C CG A LYS A 1 695 ? 23.241 73.215 -35.481 0.50 32.56 ? 695 LYS A CG 1 ATOM 5550 C CG B LYS A 1 695 ? 23.302 72.967 -35.648 0.50 32.07 ? 695 LYS A CG 1 ATOM 5551 C CD A LYS A 1 695 ? 22.986 74.268 -36.568 0.50 34.04 ? 695 LYS A CD 1 ATOM 5552 C CD B LYS A 1 695 ? 22.834 74.154 -36.498 0.50 34.39 ? 695 LYS A CD 1 ATOM 5553 C CE A LYS A 1 695 ? 21.542 74.254 -37.045 0.50 35.52 ? 695 LYS A CE 1 ATOM 5554 C CE B LYS A 1 695 ? 22.445 75.338 -35.621 0.50 35.37 ? 695 LYS A CE 1 ATOM 5555 N NZ A LYS A 1 695 ? 21.371 75.131 -38.224 0.50 35.10 ? 695 LYS A NZ 1 ATOM 5556 N NZ B LYS A 1 695 ? 21.203 75.068 -34.852 0.50 36.91 ? 695 LYS A NZ 1 ATOM 5557 N N . SER A 1 696 ? 26.276 70.608 -35.152 1.00 19.60 ? 696 SER A N 1 ATOM 5558 C CA . SER A 1 696 ? 26.406 69.285 -35.758 1.00 17.99 ? 696 SER A CA 1 ATOM 5559 C C . SER A 1 696 ? 27.839 68.895 -36.003 1.00 17.74 ? 696 SER A C 1 ATOM 5560 O O . SER A 1 696 ? 28.752 69.752 -36.059 1.00 18.87 ? 696 SER A O 1 ATOM 5561 C CB . SER A 1 696 ? 25.601 69.226 -37.085 1.00 22.50 ? 696 SER A CB 1 ATOM 5562 O OG . SER A 1 696 ? 26.243 69.967 -38.092 1.00 24.61 ? 696 SER A OG 1 ATOM 5563 N N . ILE A 1 697 ? 28.066 67.585 -36.146 1.00 18.36 ? 697 ILE A N 1 ATOM 5564 C CA . ILE A 1 697 ? 29.368 67.050 -36.433 1.00 17.33 ? 697 ILE A CA 1 ATOM 5565 C C . ILE A 1 697 ? 29.234 66.085 -37.598 1.00 22.40 ? 697 ILE A C 1 ATOM 5566 O O . ILE A 1 697 ? 28.356 65.226 -37.547 1.00 22.29 ? 697 ILE A O 1 ATOM 5567 C CB . ILE A 1 697 ? 29.946 66.252 -35.231 1.00 18.62 ? 697 ILE A CB 1 ATOM 5568 C CG1 . ILE A 1 697 ? 30.079 67.155 -34.019 1.00 19.15 ? 697 ILE A CG1 1 ATOM 5569 C CG2 . ILE A 1 697 ? 31.269 65.687 -35.608 1.00 19.50 ? 697 ILE A CG2 1 ATOM 5570 C CD1 . ILE A 1 697 ? 30.523 66.375 -32.759 1.00 19.07 ? 697 ILE A CD1 1 ATOM 5571 N N . GLN A 1 698 ? 30.086 66.243 -38.612 1.00 20.32 ? 698 GLN A N 1 ATOM 5572 C CA . GLN A 1 698 ? 30.095 65.362 -39.777 1.00 22.18 ? 698 GLN A CA 1 ATOM 5573 C C . GLN A 1 698 ? 31.439 64.692 -39.721 1.00 21.95 ? 698 GLN A C 1 ATOM 5574 O O . GLN A 1 698 ? 32.489 65.323 -39.907 1.00 23.62 ? 698 GLN A O 1 ATOM 5575 C CB . GLN A 1 698 ? 29.945 66.163 -41.075 1.00 24.98 ? 698 GLN A CB 1 ATOM 5576 C CG . GLN A 1 698 ? 30.015 65.252 -42.304 1.00 27.88 ? 698 GLN A CG 1 ATOM 5577 C CD . GLN A 1 698 ? 30.056 66.048 -43.577 1.00 31.27 ? 698 GLN A CD 1 ATOM 5578 O OE1 . GLN A 1 698 ? 29.188 65.903 -44.432 1.00 34.72 ? 698 GLN A OE1 1 ATOM 5579 N NE2 . GLN A 1 698 ? 31.054 66.904 -43.705 1.00 29.88 ? 698 GLN A NE2 1 ATOM 5580 N N . LEU A 1 699 ? 31.439 63.389 -39.465 1.00 23.55 ? 699 LEU A N 1 ATOM 5581 C CA . LEU A 1 699 ? 32.693 62.679 -39.310 1.00 27.26 ? 699 LEU A CA 1 ATOM 5582 C C . LEU A 1 699 ? 33.579 62.597 -40.533 1.00 29.50 ? 699 LEU A C 1 ATOM 5583 O O . LEU A 1 699 ? 34.798 62.719 -40.425 1.00 29.11 ? 699 LEU A O 1 ATOM 5584 C CB . LEU A 1 699 ? 32.437 61.262 -38.770 1.00 28.12 ? 699 LEU A CB 1 ATOM 5585 C CG . LEU A 1 699 ? 31.774 61.179 -37.386 1.00 27.74 ? 699 LEU A CG 1 ATOM 5586 C CD1 . LEU A 1 699 ? 31.696 59.706 -36.933 1.00 28.25 ? 699 LEU A CD1 1 ATOM 5587 C CD2 . LEU A 1 699 ? 32.574 61.992 -36.407 1.00 28.52 ? 699 LEU A CD2 1 ATOM 5588 N N . THR A 1 700 ? 32.972 62.404 -41.698 1.00 32.56 ? 700 THR A N 1 ATOM 5589 C CA . THR A 1 700 ? 33.730 62.266 -42.936 1.00 37.44 ? 700 THR A CA 1 ATOM 5590 C C . THR A 1 700 ? 33.012 62.995 -44.061 1.00 38.99 ? 700 THR A C 1 ATOM 5591 O O . THR A 1 700 ? 31.848 63.353 -43.922 1.00 40.13 ? 700 THR A O 1 ATOM 5592 C CB . THR A 1 700 ? 33.883 60.768 -43.336 1.00 36.94 ? 700 THR A CB 1 ATOM 5593 O OG1 . THR A 1 700 ? 32.584 60.198 -43.581 1.00 38.62 ? 700 THR A OG1 1 ATOM 5594 C CG2 . THR A 1 700 ? 34.552 59.982 -42.223 1.00 37.54 ? 700 THR A CG2 1 ATOM 5595 N N . GLN A 1 701 ? 33.718 63.201 -45.173 1.00 43.70 ? 701 GLN A N 1 ATOM 5596 C CA . GLN A 1 701 ? 33.173 63.883 -46.345 1.00 47.52 ? 701 GLN A CA 1 ATOM 5597 C C . GLN A 1 701 ? 31.760 63.454 -46.721 1.00 48.01 ? 701 GLN A C 1 ATOM 5598 O O . GLN A 1 701 ? 30.874 64.298 -46.915 1.00 49.45 ? 701 GLN A O 1 ATOM 5599 C CB . GLN A 1 701 ? 34.088 63.661 -47.556 1.00 50.54 ? 701 GLN A CB 1 ATOM 5600 C CG . GLN A 1 701 ? 35.355 64.508 -47.563 1.00 54.58 ? 701 GLN A CG 1 ATOM 5601 C CD . GLN A 1 701 ? 35.067 65.988 -47.796 1.00 57.84 ? 701 GLN A CD 1 ATOM 5602 O OE1 . GLN A 1 701 ? 35.989 66.815 -47.838 1.00 59.39 ? 701 GLN A OE1 1 ATOM 5603 N NE2 . GLN A 1 701 ? 33.784 66.332 -47.948 1.00 59.56 ? 701 GLN A NE2 1 ATOM 5604 N N . ASP A 1 702 ? 31.548 62.148 -46.816 1.00 48.38 ? 702 ASP A N 1 ATOM 5605 C CA . ASP A 1 702 ? 30.240 61.611 -47.190 1.00 50.33 ? 702 ASP A CA 1 ATOM 5606 C C . ASP A 1 702 ? 29.161 61.632 -46.102 1.00 49.45 ? 702 ASP A C 1 ATOM 5607 O O . ASP A 1 702 ? 28.027 62.086 -46.340 1.00 49.64 ? 702 ASP A O 1 ATOM 5608 C CB . ASP A 1 702 ? 30.403 60.172 -47.712 1.00 53.18 ? 702 ASP A CB 1 ATOM 5609 C CG . ASP A 1 702 ? 31.068 59.246 -46.696 1.00 55.78 ? 702 ASP A CG 1 ATOM 5610 O OD1 . ASP A 1 702 ? 32.242 59.500 -46.328 1.00 56.93 ? 702 ASP A OD1 1 ATOM 5611 O OD2 . ASP A 1 702 ? 30.414 58.263 -46.268 1.00 57.27 ? 702 ASP A OD2 1 ATOM 5612 N N . SER A 1 703 ? 29.534 61.149 -44.916 1.00 46.53 ? 703 SER A N 1 ATOM 5613 C CA . SER A 1 703 ? 28.649 61.033 -43.759 1.00 43.00 ? 703 SER A CA 1 ATOM 5614 C C . SER A 1 703 ? 27.718 62.192 -43.462 1.00 40.25 ? 703 SER A C 1 ATOM 5615 O O . SER A 1 703 ? 27.963 63.323 -43.867 1.00 40.44 ? 703 SER A O 1 ATOM 5616 C CB . SER A 1 703 ? 29.483 60.720 -42.508 1.00 43.99 ? 703 SER A CB 1 ATOM 5617 O OG . SER A 1 703 ? 30.365 61.783 -42.179 1.00 41.89 ? 703 SER A OG 1 ATOM 5618 N N . PRO A 1 704 ? 26.631 61.918 -42.719 1.00 38.47 ? 704 PRO A N 1 ATOM 5619 C CA . PRO A 1 704 ? 25.664 62.946 -42.361 1.00 36.85 ? 704 PRO A CA 1 ATOM 5620 C C . PRO A 1 704 ? 26.146 63.926 -41.295 1.00 35.81 ? 704 PRO A C 1 ATOM 5621 O O . PRO A 1 704 ? 27.106 63.677 -40.550 1.00 32.61 ? 704 PRO A O 1 ATOM 5622 C CB . PRO A 1 704 ? 24.468 62.141 -41.875 1.00 38.86 ? 704 PRO A CB 1 ATOM 5623 C CG . PRO A 1 704 ? 25.093 60.945 -41.281 1.00 39.42 ? 704 PRO A CG 1 ATOM 5624 C CD . PRO A 1 704 ? 26.168 60.592 -42.269 1.00 38.74 ? 704 PRO A CD 1 ATOM 5625 N N . HIS A 1 705 ? 25.449 65.050 -41.246 1.00 34.22 ? 705 HIS A N 1 ATOM 5626 C CA . HIS A 1 705 ? 25.728 66.080 -40.263 1.00 31.95 ? 705 HIS A CA 1 ATOM 5627 C C . HIS A 1 705 ? 24.871 65.684 -39.065 1.00 29.36 ? 705 HIS A C 1 ATOM 5628 O O . HIS A 1 705 ? 23.692 65.996 -38.982 1.00 29.24 ? 705 HIS A O 1 ATOM 5629 C CB . HIS A 1 705 ? 25.349 67.461 -40.831 1.00 34.70 ? 705 HIS A CB 1 ATOM 5630 C CG . HIS A 1 705 ? 26.234 67.898 -41.967 1.00 36.50 ? 705 HIS A CG 1 ATOM 5631 N ND1 . HIS A 1 705 ? 27.449 68.521 -41.766 1.00 36.23 ? 705 HIS A ND1 1 ATOM 5632 C CD2 . HIS A 1 705 ? 26.140 67.688 -43.304 1.00 36.91 ? 705 HIS A CD2 1 ATOM 5633 C CE1 . HIS A 1 705 ? 28.072 68.662 -42.924 1.00 38.78 ? 705 HIS A CE1 1 ATOM 5634 N NE2 . HIS A 1 705 ? 27.298 68.163 -43.875 1.00 38.03 ? 705 HIS A NE2 1 ATOM 5635 N N . VAL A 1 706 ? 25.510 65.014 -38.102 1.00 25.06 ? 706 VAL A N 1 ATOM 5636 C CA . VAL A 1 706 ? 24.843 64.526 -36.906 1.00 22.41 ? 706 VAL A CA 1 ATOM 5637 C C . VAL A 1 706 ? 24.522 65.629 -35.917 1.00 21.22 ? 706 VAL A C 1 ATOM 5638 O O . VAL A 1 706 ? 25.423 66.326 -35.446 1.00 21.44 ? 706 VAL A O 1 ATOM 5639 C CB . VAL A 1 706 ? 25.768 63.469 -36.214 1.00 22.01 ? 706 VAL A CB 1 ATOM 5640 C CG1 . VAL A 1 706 ? 25.073 62.867 -35.007 1.00 24.47 ? 706 VAL A CG1 1 ATOM 5641 C CG2 . VAL A 1 706 ? 26.191 62.413 -37.224 1.00 22.84 ? 706 VAL A CG2 1 ATOM 5642 N N . PRO A 1 707 ? 23.256 65.814 -35.574 1.00 21.37 ? 707 PRO A N 1 ATOM 5643 C CA . PRO A 1 707 ? 22.924 66.866 -34.620 1.00 20.40 ? 707 PRO A CA 1 ATOM 5644 C C . PRO A 1 707 ? 23.620 66.608 -33.270 1.00 20.94 ? 707 PRO A C 1 ATOM 5645 O O . PRO A 1 707 ? 23.469 65.527 -32.676 1.00 23.14 ? 707 PRO A O 1 ATOM 5646 C CB . PRO A 1 707 ? 21.403 66.766 -34.494 1.00 22.82 ? 707 PRO A CB 1 ATOM 5647 C CG . PRO A 1 707 ? 20.981 66.098 -35.791 1.00 24.21 ? 707 PRO A CG 1 ATOM 5648 C CD . PRO A 1 707 ? 22.039 65.080 -35.998 1.00 21.34 ? 707 PRO A CD 1 ATOM 5649 N N . VAL A 1 708 ? 24.373 67.605 -32.802 1.00 20.35 ? 708 VAL A N 1 ATOM 5650 C CA . VAL A 1 708 ? 25.095 67.565 -31.507 1.00 16.86 ? 708 VAL A CA 1 ATOM 5651 C C . VAL A 1 708 ? 25.044 69.042 -31.147 1.00 17.08 ? 708 VAL A C 1 ATOM 5652 O O . VAL A 1 708 ? 25.807 69.861 -31.693 1.00 21.16 ? 708 VAL A O 1 ATOM 5653 C CB . VAL A 1 708 ? 26.536 67.082 -31.654 1.00 17.84 ? 708 VAL A CB 1 ATOM 5654 C CG1 . VAL A 1 708 ? 27.208 67.102 -30.273 1.00 17.56 ? 708 VAL A CG1 1 ATOM 5655 C CG2 . VAL A 1 708 ? 26.564 65.622 -32.176 1.00 19.79 ? 708 VAL A CG2 1 ATOM 5656 N N . HIS A 1 709 ? 24.143 69.395 -30.242 1.00 16.22 ? 709 HIS A N 1 ATOM 5657 C CA . HIS A 1 709 ? 23.932 70.800 -29.879 1.00 17.75 ? 709 HIS A CA 1 ATOM 5658 C C . HIS A 1 709 ? 24.323 71.178 -28.450 1.00 17.88 ? 709 HIS A C 1 ATOM 5659 O O A HIS A 1 709 ? 23.765 70.631 -27.484 0.50 17.94 ? 709 HIS A O 1 ATOM 5660 O O B HIS A 1 709 ? 24.039 70.365 -27.585 0.50 18.78 ? 709 HIS A O 1 ATOM 5661 C CB . HIS A 1 709 ? 22.448 71.177 -30.067 1.00 20.74 ? 709 HIS A CB 1 ATOM 5662 C CG A HIS A 1 709 ? 21.972 71.164 -31.487 0.50 23.21 ? 709 HIS A CG 1 ATOM 5663 C CG B HIS A 1 709 ? 22.299 72.670 -29.861 0.50 23.29 ? 709 HIS A CG 1 ATOM 5664 N ND1 A HIS A 1 709 ? 21.316 72.237 -32.056 0.50 26.83 ? 709 HIS A ND1 1 ATOM 5665 N ND1 B HIS A 1 709 ? 23.065 73.705 -30.358 0.50 25.59 ? 709 HIS A ND1 1 ATOM 5666 C CD2 A HIS A 1 709 ? 22.006 70.200 -32.437 0.50 24.29 ? 709 HIS A CD2 1 ATOM 5667 C CD2 B HIS A 1 709 ? 21.303 73.249 -29.148 0.50 25.08 ? 709 HIS A CD2 1 ATOM 5668 C CE1 A HIS A 1 709 ? 20.967 71.932 -33.294 0.50 25.44 ? 709 HIS A CE1 1 ATOM 5669 C CE1 B HIS A 1 709 ? 22.551 74.857 -29.966 0.50 24.28 ? 709 HIS A CE1 1 ATOM 5670 N NE2 A HIS A 1 709 ? 21.375 70.701 -33.549 0.50 20.28 ? 709 HIS A NE2 1 ATOM 5671 N NE2 B HIS A 1 709 ? 21.482 74.609 -29.232 0.50 26.07 ? 709 HIS A NE2 1 ATOM 5672 N N . PHE A 1 710 ? 25.253 72.124 -28.302 1.00 16.25 ? 710 PHE A N 1 ATOM 5673 C CA . PHE A 1 710 ? 25.638 72.566 -26.974 1.00 16.98 ? 710 PHE A CA 1 ATOM 5674 C C . PHE A 1 710 ? 24.631 73.656 -26.538 1.00 17.52 ? 710 PHE A C 1 ATOM 5675 O O . PHE A 1 710 ? 24.180 74.501 -27.360 1.00 17.73 ? 710 PHE A O 1 ATOM 5676 C CB . PHE A 1 710 ? 27.046 73.177 -26.937 1.00 17.93 ? 710 PHE A CB 1 ATOM 5677 C CG . PHE A 1 710 ? 28.147 72.208 -26.548 1.00 17.83 ? 710 PHE A CG 1 ATOM 5678 C CD1 . PHE A 1 710 ? 28.093 71.537 -25.344 1.00 20.69 ? 710 PHE A CD1 1 ATOM 5679 C CD2 . PHE A 1 710 ? 29.251 72.003 -27.374 1.00 20.76 ? 710 PHE A CD2 1 ATOM 5680 C CE1 . PHE A 1 710 ? 29.122 70.664 -24.948 1.00 21.24 ? 710 PHE A CE1 1 ATOM 5681 C CE2 . PHE A 1 710 ? 30.288 71.128 -26.959 1.00 19.80 ? 710 PHE A CE2 1 ATOM 5682 C CZ . PHE A 1 710 ? 30.206 70.482 -25.770 1.00 20.62 ? 710 PHE A CZ 1 ATOM 5683 N N . LYS A 1 711 ? 24.283 73.656 -25.274 1.00 16.42 ? 711 LYS A N 1 ATOM 5684 C CA . LYS A 1 711 ? 23.371 74.619 -24.709 1.00 17.53 ? 711 LYS A CA 1 ATOM 5685 C C . LYS A 1 711 ? 23.722 74.834 -23.252 1.00 17.71 ? 711 LYS A C 1 ATOM 5686 O O . LYS A 1 711 ? 24.076 73.866 -22.555 1.00 19.33 ? 711 LYS A O 1 ATOM 5687 C CB . LYS A 1 711 ? 21.913 74.111 -24.820 1.00 20.20 ? 711 LYS A CB 1 ATOM 5688 C CG . LYS A 1 711 ? 20.880 75.041 -24.241 1.00 24.51 ? 711 LYS A CG 1 ATOM 5689 C CD . LYS A 1 711 ? 19.455 74.457 -24.406 1.00 29.78 ? 711 LYS A CD 1 ATOM 5690 C CE . LYS A 1 711 ? 19.073 74.396 -25.898 1.00 29.84 ? 711 LYS A CE 1 ATOM 5691 N NZ . LYS A 1 711 ? 17.735 73.720 -26.070 1.00 31.38 ? 711 LYS A NZ 1 ATOM 5692 N N . PHE A 1 712 ? 23.645 76.068 -22.784 1.00 15.78 ? 712 PHE A N 1 ATOM 5693 C CA . PHE A 1 712 ? 23.867 76.405 -21.411 1.00 15.92 ? 712 PHE A CA 1 ATOM 5694 C C . PHE A 1 712 ? 22.560 76.750 -20.731 1.00 16.85 ? 712 PHE A C 1 ATOM 5695 O O . PHE A 1 712 ? 21.745 77.502 -21.275 1.00 17.06 ? 712 PHE A O 1 ATOM 5696 C CB . PHE A 1 712 ? 24.884 77.554 -21.243 1.00 17.83 ? 712 PHE A CB 1 ATOM 5697 C CG . PHE A 1 712 ? 26.306 77.149 -21.558 1.00 16.21 ? 712 PHE A CG 1 ATOM 5698 C CD1 . PHE A 1 712 ? 26.776 77.205 -22.852 1.00 17.44 ? 712 PHE A CD1 1 ATOM 5699 C CD2 . PHE A 1 712 ? 27.157 76.643 -20.557 1.00 16.63 ? 712 PHE A CD2 1 ATOM 5700 C CE1 . PHE A 1 712 ? 28.049 76.768 -23.184 1.00 15.45 ? 712 PHE A CE1 1 ATOM 5701 C CE2 . PHE A 1 712 ? 28.412 76.221 -20.878 1.00 15.66 ? 712 PHE A CE2 1 ATOM 5702 C CZ . PHE A 1 712 ? 28.878 76.270 -22.179 1.00 16.87 ? 712 PHE A CZ 1 ATOM 5703 N N . LEU A 1 713 ? 22.328 76.144 -19.579 1.00 15.04 ? 713 LEU A N 1 ATOM 5704 C CA . LEU A 1 713 ? 21.097 76.367 -18.811 1.00 15.23 ? 713 LEU A CA 1 ATOM 5705 C C . LEU A 1 713 ? 21.439 76.640 -17.363 1.00 15.21 ? 713 LEU A C 1 ATOM 5706 O O . LEU A 1 713 ? 22.626 76.544 -16.932 1.00 16.52 ? 713 LEU A O 1 ATOM 5707 C CB . LEU A 1 713 ? 20.145 75.163 -18.899 1.00 16.34 ? 713 LEU A CB 1 ATOM 5708 C CG . LEU A 1 713 ? 19.842 74.709 -20.318 1.00 16.16 ? 713 LEU A CG 1 ATOM 5709 C CD1 . LEU A 1 713 ? 20.728 73.527 -20.693 1.00 17.56 ? 713 LEU A CD1 1 ATOM 5710 C CD2 . LEU A 1 713 ? 18.355 74.223 -20.406 1.00 18.18 ? 713 LEU A CD2 1 ATOM 5711 N N . LYS A 1 714 ? 20.418 77.006 -16.592 1.00 15.57 ? 714 LYS A N 1 ATOM 5712 C CA . LYS A 1 714 ? 20.611 77.287 -15.206 1.00 16.34 ? 714 LYS A CA 1 ATOM 5713 C C . LYS A 1 714 ? 19.593 76.637 -14.316 1.00 18.33 ? 714 LYS A C 1 ATOM 5714 O O . LYS A 1 714 ? 18.398 76.578 -14.632 1.00 18.63 ? 714 LYS A O 1 ATOM 5715 C CB . LYS A 1 714 ? 20.563 78.783 -14.936 1.00 22.79 ? 714 LYS A CB 1 ATOM 5716 C CG . LYS A 1 714 ? 19.423 79.488 -15.601 1.00 29.73 ? 714 LYS A CG 1 ATOM 5717 C CD . LYS A 1 714 ? 19.490 81.001 -15.308 1.00 34.24 ? 714 LYS A CD 1 ATOM 5718 C CE . LYS A 1 714 ? 20.879 81.592 -15.507 1.00 38.37 ? 714 LYS A CE 1 ATOM 5719 N NZ . LYS A 1 714 ? 20.915 83.083 -15.261 1.00 43.04 ? 714 LYS A NZ 1 ATOM 5720 N N . TYR A 1 715 ? 20.088 76.126 -13.192 1.00 15.04 ? 715 TYR A N 1 ATOM 5721 C CA . TYR A 1 715 ? 19.218 75.592 -12.168 1.00 15.35 ? 715 TYR A CA 1 ATOM 5722 C C . TYR A 1 715 ? 19.171 76.633 -11.060 1.00 18.16 ? 715 TYR A C 1 ATOM 5723 O O . TYR A 1 715 ? 20.135 77.390 -10.813 1.00 18.41 ? 715 TYR A O 1 ATOM 5724 C CB . TYR A 1 715 ? 19.790 74.308 -11.533 1.00 15.56 ? 715 TYR A CB 1 ATOM 5725 C CG . TYR A 1 715 ? 19.706 73.096 -12.382 1.00 13.57 ? 715 TYR A CG 1 ATOM 5726 C CD1 . TYR A 1 715 ? 18.514 72.345 -12.441 1.00 14.32 ? 715 TYR A CD1 1 ATOM 5727 C CD2 . TYR A 1 715 ? 20.814 72.648 -13.149 1.00 13.29 ? 715 TYR A CD2 1 ATOM 5728 C CE1 . TYR A 1 715 ? 18.437 71.212 -13.212 1.00 15.82 ? 715 TYR A CE1 1 ATOM 5729 C CE2 . TYR A 1 715 ? 20.731 71.504 -13.934 1.00 14.07 ? 715 TYR A CE2 1 ATOM 5730 C CZ . TYR A 1 715 ? 19.530 70.780 -13.959 1.00 16.02 ? 715 TYR A CZ 1 ATOM 5731 O OH . TYR A 1 715 ? 19.397 69.632 -14.664 1.00 16.45 ? 715 TYR A OH 1 ATOM 5732 N N . GLY A 1 716 ? 18.069 76.622 -10.332 1.00 17.14 ? 716 GLY A N 1 ATOM 5733 C CA . GLY A 1 716 ? 17.891 77.545 -9.246 1.00 17.53 ? 716 GLY A CA 1 ATOM 5734 C C . GLY A 1 716 ? 17.766 76.799 -7.925 1.00 18.66 ? 716 GLY A C 1 ATOM 5735 O O . GLY A 1 716 ? 18.075 75.611 -7.819 1.00 18.83 ? 716 GLY A O 1 ATOM 5736 N N . VAL A 1 717 ? 17.285 77.512 -6.922 1.00 17.30 ? 717 VAL A N 1 ATOM 5737 C CA . VAL A 1 717 ? 17.139 76.989 -5.580 1.00 19.39 ? 717 VAL A CA 1 ATOM 5738 C C . VAL A 1 717 ? 15.692 77.140 -5.148 1.00 20.75 ? 717 VAL A C 1 ATOM 5739 O O . VAL A 1 717 ? 15.004 78.067 -5.587 1.00 22.36 ? 717 VAL A O 1 ATOM 5740 C CB . VAL A 1 717 ? 18.102 77.758 -4.622 1.00 18.85 ? 717 VAL A CB 1 ATOM 5741 C CG1 . VAL A 1 717 ? 17.916 77.335 -3.196 1.00 22.20 ? 717 VAL A CG1 1 ATOM 5742 C CG2 . VAL A 1 717 ? 19.561 77.513 -5.052 1.00 19.87 ? 717 VAL A CG2 1 ATOM 5743 N N . ARG A 1 718 ? 15.244 76.251 -4.273 1.00 20.63 ? 718 ARG A N 1 ATOM 5744 C CA . ARG A 1 718 ? 13.873 76.288 -3.782 1.00 22.09 ? 718 ARG A CA 1 ATOM 5745 C C . ARG A 1 718 ? 13.645 77.461 -2.861 1.00 24.39 ? 718 ARG A C 1 ATOM 5746 O O . ARG A 1 718 ? 14.512 77.858 -2.096 1.00 27.48 ? 718 ARG A O 1 ATOM 5747 C CB . ARG A 1 718 ? 13.525 74.963 -3.068 1.00 19.09 ? 718 ARG A CB 1 ATOM 5748 C CG . ARG A 1 718 ? 13.565 73.784 -4.013 1.00 19.29 ? 718 ARG A CG 1 ATOM 5749 C CD . ARG A 1 718 ? 13.542 72.448 -3.290 1.00 19.27 ? 718 ARG A CD 1 ATOM 5750 N NE . ARG A 1 718 ? 13.834 71.422 -4.266 1.00 20.82 ? 718 ARG A NE 1 ATOM 5751 C CZ . ARG A 1 718 ? 13.768 70.115 -4.024 1.00 21.85 ? 718 ARG A CZ 1 ATOM 5752 N NH1 . ARG A 1 718 ? 13.398 69.681 -2.827 1.00 21.98 ? 718 ARG A NH1 1 ATOM 5753 N NH2 . ARG A 1 718 ? 14.109 69.268 -4.988 1.00 22.68 ? 718 ARG A NH2 1 ATOM 5754 N N . SER A 1 719 ? 12.454 78.030 -2.965 1.00 25.73 ? 719 SER A N 1 ATOM 5755 C CA . SER A 1 719 ? 12.097 79.174 -2.137 1.00 28.57 ? 719 SER A CA 1 ATOM 5756 C C . SER A 1 719 ? 11.422 78.696 -0.869 1.00 30.70 ? 719 SER A C 1 ATOM 5757 O O . SER A 1 719 ? 11.247 79.459 0.058 1.00 32.60 ? 719 SER A O 1 ATOM 5758 C CB . SER A 1 719 ? 11.164 80.116 -2.918 1.00 29.99 ? 719 SER A CB 1 ATOM 5759 O OG . SER A 1 719 ? 10.039 79.408 -3.388 1.00 33.46 ? 719 SER A OG 1 ATOM 5760 N N . HIS A 1 720 ? 11.010 77.436 -0.841 1.00 31.88 ? 720 HIS A N 1 ATOM 5761 C CA . HIS A 1 720 ? 10.431 76.883 0.364 1.00 33.70 ? 720 HIS A CA 1 ATOM 5762 C C . HIS A 1 720 ? 10.971 75.440 0.462 1.00 32.65 ? 720 HIS A C 1 ATOM 5763 O O . HIS A 1 720 ? 11.245 74.783 -0.552 1.00 32.22 ? 720 HIS A O 1 ATOM 5764 C CB . HIS A 1 720 ? 8.889 76.998 0.318 1.00 37.49 ? 720 HIS A CB 1 ATOM 5765 C CG . HIS A 1 720 ? 8.200 75.882 -0.395 1.00 42.51 ? 720 HIS A CG 1 ATOM 5766 N ND1 . HIS A 1 720 ? 7.637 74.812 0.272 1.00 44.73 ? 720 HIS A ND1 1 ATOM 5767 C CD2 . HIS A 1 720 ? 7.959 75.677 -1.713 1.00 45.35 ? 720 HIS A CD2 1 ATOM 5768 C CE1 . HIS A 1 720 ? 7.077 73.995 -0.605 1.00 47.18 ? 720 HIS A CE1 1 ATOM 5769 N NE2 . HIS A 1 720 ? 7.258 74.496 -1.818 1.00 48.43 ? 720 HIS A NE2 1 ATOM 5770 N N . GLY A 1 721 ? 11.165 74.962 1.679 1.00 30.81 ? 721 GLY A N 1 ATOM 5771 C CA . GLY A 1 721 ? 11.719 73.631 1.841 1.00 30.31 ? 721 GLY A CA 1 ATOM 5772 C C . GLY A 1 721 ? 13.244 73.683 2.027 1.00 30.04 ? 721 GLY A C 1 ATOM 5773 O O . GLY A 1 721 ? 13.812 74.700 2.444 1.00 29.16 ? 721 GLY A O 1 ATOM 5774 N N . ASP A 1 722 ? 13.922 72.592 1.679 1.00 26.87 ? 722 ASP A N 1 ATOM 5775 C CA . ASP A 1 722 ? 15.372 72.518 1.885 1.00 24.52 ? 722 ASP A CA 1 ATOM 5776 C C . ASP A 1 722 ? 16.131 73.215 0.770 1.00 20.76 ? 722 ASP A C 1 ATOM 5777 O O . ASP A 1 722 ? 15.745 73.155 -0.383 1.00 21.16 ? 722 ASP A O 1 ATOM 5778 C CB . ASP A 1 722 ? 15.815 71.051 1.992 1.00 21.80 ? 722 ASP A CB 1 ATOM 5779 C CG . ASP A 1 722 ? 15.155 70.310 3.170 1.00 23.04 ? 722 ASP A CG 1 ATOM 5780 O OD1 . ASP A 1 722 ? 14.912 70.911 4.244 1.00 23.99 ? 722 ASP A OD1 1 ATOM 5781 O OD2 . ASP A 1 722 ? 14.876 69.105 3.025 1.00 23.16 ? 722 ASP A OD2 1 ATOM 5782 N N . ARG A 1 723 ? 17.194 73.903 1.165 1.00 19.51 ? 723 ARG A N 1 ATOM 5783 C CA . ARG A 1 723 ? 18.031 74.634 0.232 1.00 20.35 ? 723 ARG A CA 1 ATOM 5784 C C . ARG A 1 723 ? 19.297 73.896 -0.186 1.00 19.05 ? 723 ARG A C 1 ATOM 5785 O O . ARG A 1 723 ? 19.946 73.230 0.628 1.00 18.06 ? 723 ARG A O 1 ATOM 5786 C CB . ARG A 1 723 ? 18.452 75.974 0.852 1.00 22.90 ? 723 ARG A CB 1 ATOM 5787 C CG . ARG A 1 723 ? 17.423 77.108 0.732 1.00 32.46 ? 723 ARG A CG 1 ATOM 5788 C CD . ARG A 1 723 ? 16.215 76.874 1.614 1.00 39.81 ? 723 ARG A CD 1 ATOM 5789 N NE . ARG A 1 723 ? 15.206 77.942 1.539 1.00 44.91 ? 723 ARG A NE 1 ATOM 5790 C CZ . ARG A 1 723 ? 15.445 79.225 1.804 1.00 48.52 ? 723 ARG A CZ 1 ATOM 5791 N NH1 . ARG A 1 723 ? 16.670 79.627 2.146 1.00 50.14 ? 723 ARG A NH1 1 ATOM 5792 N NH2 . ARG A 1 723 ? 14.445 80.101 1.788 1.00 48.57 ? 723 ARG A NH2 1 ATOM 5793 N N . SER A 1 724 ? 19.630 74.033 -1.467 1.00 18.05 ? 724 SER A N 1 ATOM 5794 C CA . SER A 1 724 ? 20.870 73.504 -2.002 1.00 16.91 ? 724 SER A CA 1 ATOM 5795 C C . SER A 1 724 ? 22.009 74.207 -1.250 1.00 17.78 ? 724 SER A C 1 ATOM 5796 O O . SER A 1 724 ? 21.890 75.378 -0.857 1.00 19.24 ? 724 SER A O 1 ATOM 5797 C CB . SER A 1 724 ? 20.998 73.867 -3.475 1.00 18.04 ? 724 SER A CB 1 ATOM 5798 O OG . SER A 1 724 ? 19.979 73.230 -4.216 1.00 17.10 ? 724 SER A OG 1 ATOM 5799 N N . GLY A 1 725 ? 23.135 73.510 -1.098 1.00 15.24 ? 725 GLY A N 1 ATOM 5800 C CA . GLY A 1 725 ? 24.304 74.088 -0.441 1.00 15.40 ? 725 GLY A CA 1 ATOM 5801 C C . GLY A 1 725 ? 25.531 73.365 -1.004 1.00 13.09 ? 725 GLY A C 1 ATOM 5802 O O . GLY A 1 725 ? 25.431 72.694 -2.045 1.00 15.44 ? 725 GLY A O 1 ATOM 5803 N N . ALA A 1 726 ? 26.673 73.472 -0.328 1.00 13.83 ? 726 ALA A N 1 ATOM 5804 C CA . ALA A 1 726 ? 27.915 72.822 -0.795 1.00 12.07 ? 726 ALA A CA 1 ATOM 5805 C C . ALA A 1 726 ? 27.759 71.296 -0.994 1.00 12.55 ? 726 ALA A C 1 ATOM 5806 O O . ALA A 1 726 ? 28.398 70.723 -1.882 1.00 13.43 ? 726 ALA A O 1 ATOM 5807 C CB . ALA A 1 726 ? 29.062 73.071 0.220 1.00 14.25 ? 726 ALA A CB 1 ATOM 5808 N N . TYR A 1 727 ? 26.931 70.652 -0.164 1.00 12.79 ? 727 TYR A N 1 ATOM 5809 C CA . TYR A 1 727 ? 26.732 69.199 -0.266 1.00 12.27 ? 727 TYR A CA 1 ATOM 5810 C C . TYR A 1 727 ? 25.530 68.802 -1.106 1.00 13.67 ? 727 TYR A C 1 ATOM 5811 O O . TYR A 1 727 ? 25.659 67.978 -2.023 1.00 13.92 ? 727 TYR A O 1 ATOM 5812 C CB . TYR A 1 727 ? 26.510 68.580 1.120 1.00 13.91 ? 727 TYR A CB 1 ATOM 5813 C CG . TYR A 1 727 ? 27.614 68.787 2.128 1.00 14.68 ? 727 TYR A CG 1 ATOM 5814 C CD1 . TYR A 1 727 ? 27.628 69.905 2.951 1.00 14.45 ? 727 TYR A CD1 1 ATOM 5815 C CD2 . TYR A 1 727 ? 28.633 67.862 2.268 1.00 13.94 ? 727 TYR A CD2 1 ATOM 5816 C CE1 . TYR A 1 727 ? 28.631 70.101 3.902 1.00 14.59 ? 727 TYR A CE1 1 ATOM 5817 C CE2 . TYR A 1 727 ? 29.646 68.046 3.228 1.00 15.31 ? 727 TYR A CE2 1 ATOM 5818 C CZ . TYR A 1 727 ? 29.632 69.159 4.027 1.00 16.19 ? 727 TYR A CZ 1 ATOM 5819 O OH . TYR A 1 727 ? 30.665 69.305 4.944 1.00 16.91 ? 727 TYR A OH 1 ATOM 5820 N N . LEU A 1 728 ? 24.380 69.422 -0.838 1.00 15.11 ? 728 LEU A N 1 ATOM 5821 C CA . LEU A 1 728 ? 23.139 69.011 -1.516 1.00 13.64 ? 728 LEU A CA 1 ATOM 5822 C C . LEU A 1 728 ? 22.767 69.757 -2.782 1.00 13.80 ? 728 LEU A C 1 ATOM 5823 O O . LEU A 1 728 ? 23.006 70.967 -2.866 1.00 14.55 ? 728 LEU A O 1 ATOM 5824 C CB . LEU A 1 728 ? 21.956 69.219 -0.538 1.00 14.80 ? 728 LEU A CB 1 ATOM 5825 C CG . LEU A 1 728 ? 22.119 68.627 0.849 1.00 13.88 ? 728 LEU A CG 1 ATOM 5826 C CD1 . LEU A 1 728 ? 20.781 68.843 1.652 1.00 18.86 ? 728 LEU A CD1 1 ATOM 5827 C CD2 . LEU A 1 728 ? 22.451 67.160 0.767 1.00 16.18 ? 728 LEU A CD2 1 ATOM 5828 N N . PHE A 1 729 ? 22.195 69.047 -3.751 1.00 14.74 ? 729 PHE A N 1 ATOM 5829 C CA . PHE A 1 729 ? 21.662 69.632 -4.971 1.00 14.40 ? 729 PHE A CA 1 ATOM 5830 C C . PHE A 1 729 ? 20.121 69.424 -4.849 1.00 14.85 ? 729 PHE A C 1 ATOM 5831 O O . PHE A 1 729 ? 19.616 68.292 -4.908 1.00 15.38 ? 729 PHE A O 1 ATOM 5832 C CB . PHE A 1 729 ? 22.238 68.902 -6.195 1.00 13.86 ? 729 PHE A CB 1 ATOM 5833 C CG . PHE A 1 729 ? 21.699 69.389 -7.528 1.00 13.60 ? 729 PHE A CG 1 ATOM 5834 C CD1 . PHE A 1 729 ? 21.375 70.747 -7.746 1.00 14.67 ? 729 PHE A CD1 1 ATOM 5835 C CD2 . PHE A 1 729 ? 21.586 68.489 -8.571 1.00 12.85 ? 729 PHE A CD2 1 ATOM 5836 C CE1 . PHE A 1 729 ? 20.940 71.157 -9.051 1.00 14.11 ? 729 PHE A CE1 1 ATOM 5837 C CE2 . PHE A 1 729 ? 21.163 68.889 -9.842 1.00 13.93 ? 729 PHE A CE2 1 ATOM 5838 C CZ . PHE A 1 729 ? 20.843 70.213 -10.077 1.00 16.03 ? 729 PHE A CZ 1 ATOM 5839 N N . LEU A 1 730 ? 19.406 70.543 -4.672 1.00 15.45 ? 730 LEU A N 1 ATOM 5840 C CA . LEU A 1 730 ? 17.949 70.537 -4.497 1.00 17.44 ? 730 LEU A CA 1 ATOM 5841 C C . LEU A 1 730 ? 17.378 71.567 -5.462 1.00 15.18 ? 730 LEU A C 1 ATOM 5842 O O . LEU A 1 730 ? 16.903 72.627 -5.040 1.00 16.97 ? 730 LEU A O 1 ATOM 5843 C CB . LEU A 1 730 ? 17.595 70.895 -3.047 1.00 16.83 ? 730 LEU A CB 1 ATOM 5844 C CG . LEU A 1 730 ? 18.001 69.845 -2.002 1.00 17.36 ? 730 LEU A CG 1 ATOM 5845 C CD1 . LEU A 1 730 ? 17.946 70.410 -0.600 1.00 16.33 ? 730 LEU A CD1 1 ATOM 5846 C CD2 . LEU A 1 730 ? 17.055 68.628 -2.149 1.00 20.60 ? 730 LEU A CD2 1 ATOM 5847 N N . PRO A 1 731 ? 17.421 71.257 -6.762 1.00 15.92 ? 731 PRO A N 1 ATOM 5848 C CA . PRO A 1 731 ? 16.916 72.213 -7.771 1.00 16.25 ? 731 PRO A CA 1 ATOM 5849 C C . PRO A 1 731 ? 15.447 72.523 -7.642 1.00 18.07 ? 731 PRO A C 1 ATOM 5850 O O . PRO A 1 731 ? 14.665 71.702 -7.164 1.00 18.21 ? 731 PRO A O 1 ATOM 5851 C CB . PRO A 1 731 ? 17.233 71.533 -9.097 1.00 16.23 ? 731 PRO A CB 1 ATOM 5852 C CG . PRO A 1 731 ? 17.150 70.016 -8.738 1.00 15.82 ? 731 PRO A CG 1 ATOM 5853 C CD . PRO A 1 731 ? 17.799 69.964 -7.376 1.00 15.36 ? 731 PRO A CD 1 ATOM 5854 N N . ASN A 1 732 ? 15.066 73.709 -8.108 1.00 19.59 ? 732 ASN A N 1 ATOM 5855 C CA . ASN A 1 732 ? 13.656 74.102 -8.093 1.00 21.89 ? 732 ASN A CA 1 ATOM 5856 C C . ASN A 1 732 ? 13.123 73.795 -9.488 1.00 20.55 ? 732 ASN A C 1 ATOM 5857 O O . ASN A 1 732 ? 12.613 74.673 -10.198 1.00 24.10 ? 732 ASN A O 1 ATOM 5858 C CB . ASN A 1 732 ? 13.519 75.589 -7.760 1.00 23.85 ? 732 ASN A CB 1 ATOM 5859 C CG . ASN A 1 732 ? 14.200 76.484 -8.776 1.00 27.16 ? 732 ASN A CG 1 ATOM 5860 O OD1 . ASN A 1 732 ? 15.198 76.114 -9.390 1.00 28.45 ? 732 ASN A OD1 1 ATOM 5861 N ND2 . ASN A 1 732 ? 13.650 77.696 -8.962 1.00 30.50 ? 732 ASN A ND2 1 ATOM 5862 N N . GLY A 1 733 ? 13.263 72.537 -9.893 1.00 18.74 ? 733 GLY A N 1 ATOM 5863 C CA . GLY A 1 733 ? 12.782 72.083 -11.182 1.00 20.25 ? 733 GLY A CA 1 ATOM 5864 C C . GLY A 1 733 ? 13.880 71.988 -12.232 1.00 18.97 ? 733 GLY A C 1 ATOM 5865 O O . GLY A 1 733 ? 15.056 72.325 -11.967 1.00 19.84 ? 733 GLY A O 1 ATOM 5866 N N . PRO A 1 734 ? 13.520 71.536 -13.435 1.00 18.10 ? 734 PRO A N 1 ATOM 5867 C CA . PRO A 1 734 ? 14.460 71.407 -14.552 1.00 17.76 ? 734 PRO A CA 1 ATOM 5868 C C . PRO A 1 734 ? 15.082 72.765 -14.837 1.00 18.99 ? 734 PRO A C 1 ATOM 5869 O O . PRO A 1 734 ? 14.488 73.827 -14.596 1.00 18.72 ? 734 PRO A O 1 ATOM 5870 C CB . PRO A 1 734 ? 13.581 70.991 -15.734 1.00 21.03 ? 734 PRO A CB 1 ATOM 5871 C CG . PRO A 1 734 ? 12.463 70.279 -15.079 1.00 23.49 ? 734 PRO A CG 1 ATOM 5872 C CD . PRO A 1 734 ? 12.188 71.006 -13.798 1.00 20.41 ? 734 PRO A CD 1 ATOM 5873 N N . ALA A 1 735 ? 16.255 72.701 -15.445 1.00 18.04 ? 735 ALA A N 1 ATOM 5874 C CA . ALA A 1 735 ? 17.008 73.902 -15.761 1.00 18.25 ? 735 ALA A CA 1 ATOM 5875 C C . ALA A 1 735 ? 16.302 74.730 -16.847 1.00 19.01 ? 735 ALA A C 1 ATOM 5876 O O . ALA A 1 735 ? 15.587 74.194 -17.669 1.00 20.73 ? 735 ALA A O 1 ATOM 5877 C CB . ALA A 1 735 ? 18.440 73.483 -16.225 1.00 16.93 ? 735 ALA A CB 1 ATOM 5878 N N . SER A 1 736 ? 16.552 76.036 -16.832 1.00 19.45 ? 736 SER A N 1 ATOM 5879 C CA . SER A 1 736 ? 15.978 76.975 -17.822 1.00 19.85 ? 736 SER A CA 1 ATOM 5880 C C . SER A 1 736 ? 17.141 77.492 -18.660 1.00 19.85 ? 736 SER A C 1 ATOM 5881 O O . SER A 1 736 ? 18.213 77.733 -18.136 1.00 19.91 ? 736 SER A O 1 ATOM 5882 C CB . SER A 1 736 ? 15.351 78.163 -17.118 1.00 23.61 ? 736 SER A CB 1 ATOM 5883 O OG . SER A 1 736 ? 14.483 77.723 -16.095 1.00 31.15 ? 736 SER A OG 1 ATOM 5884 N N . PRO A 1 737 ? 16.938 77.701 -19.960 1.00 21.38 ? 737 PRO A N 1 ATOM 5885 C CA . PRO A 1 737 ? 18.041 78.195 -20.812 1.00 24.35 ? 737 PRO A CA 1 ATOM 5886 C C . PRO A 1 737 ? 18.601 79.526 -20.368 1.00 23.27 ? 737 PRO A C 1 ATOM 5887 O O . PRO A 1 737 ? 17.869 80.371 -19.873 1.00 25.30 ? 737 PRO A O 1 ATOM 5888 C CB . PRO A 1 737 ? 17.410 78.297 -22.210 1.00 25.09 ? 737 PRO A CB 1 ATOM 5889 C CG . PRO A 1 737 ? 16.238 77.371 -22.151 1.00 25.63 ? 737 PRO A CG 1 ATOM 5890 C CD . PRO A 1 737 ? 15.696 77.529 -20.734 1.00 25.34 ? 737 PRO A CD 1 ATOM 5891 N N . VAL A 1 738 ? 19.922 79.686 -20.500 1.00 23.97 ? 738 VAL A N 1 ATOM 5892 C CA . VAL A 1 738 ? 20.555 80.963 -20.150 1.00 22.02 ? 738 VAL A CA 1 ATOM 5893 C C . VAL A 1 738 ? 20.149 81.877 -21.321 1.00 23.84 ? 738 VAL A C 1 ATOM 5894 O O . VAL A 1 738 ? 20.220 81.461 -22.476 1.00 23.93 ? 738 VAL A O 1 ATOM 5895 C CB . VAL A 1 738 ? 22.108 80.833 -20.104 1.00 22.16 ? 738 VAL A CB 1 ATOM 5896 C CG1 . VAL A 1 738 ? 22.744 82.235 -20.032 1.00 23.13 ? 738 VAL A CG1 1 ATOM 5897 C CG2 . VAL A 1 738 ? 22.567 79.991 -18.871 1.00 22.74 ? 738 VAL A CG2 1 ATOM 5898 N N . GLU A 1 739 ? 19.726 83.107 -21.049 1.00 24.61 ? 739 GLU A N 1 ATOM 5899 C CA . GLU A 1 739 ? 19.361 83.994 -22.158 1.00 26.47 ? 739 GLU A CA 1 ATOM 5900 C C . GLU A 1 739 ? 20.674 84.528 -22.701 1.00 24.10 ? 739 GLU A C 1 ATOM 5901 O O . GLU A 1 739 ? 21.440 85.176 -21.987 1.00 24.63 ? 739 GLU A O 1 ATOM 5902 C CB . GLU A 1 739 ? 18.482 85.135 -21.678 1.00 29.65 ? 739 GLU A CB 1 ATOM 5903 C CG . GLU A 1 739 ? 17.067 84.703 -21.388 1.00 38.90 ? 739 GLU A CG 1 ATOM 5904 C CD . GLU A 1 739 ? 16.205 85.872 -20.949 1.00 44.39 ? 739 GLU A CD 1 ATOM 5905 O OE1 . GLU A 1 739 ? 16.331 86.961 -21.558 1.00 45.60 ? 739 GLU A OE1 1 ATOM 5906 O OE2 . GLU A 1 739 ? 15.401 85.696 -19.999 1.00 48.93 ? 739 GLU A OE2 1 ATOM 5907 N N . LEU A 1 740 ? 20.917 84.243 -23.970 1.00 24.33 ? 740 LEU A N 1 ATOM 5908 C CA . LEU A 1 740 ? 22.191 84.597 -24.581 1.00 23.98 ? 740 LEU A CA 1 ATOM 5909 C C . LEU A 1 740 ? 22.344 85.957 -25.200 1.00 26.00 ? 740 LEU A C 1 ATOM 5910 O O . LEU A 1 740 ? 23.468 86.396 -25.356 1.00 26.01 ? 740 LEU A O 1 ATOM 5911 C CB . LEU A 1 740 ? 22.554 83.560 -25.620 1.00 25.61 ? 740 LEU A CB 1 ATOM 5912 C CG . LEU A 1 740 ? 22.523 82.105 -25.171 1.00 23.86 ? 740 LEU A CG 1 ATOM 5913 C CD1 . LEU A 1 740 ? 23.041 81.255 -26.303 1.00 21.22 ? 740 LEU A CD1 1 ATOM 5914 C CD2 . LEU A 1 740 ? 23.411 81.916 -23.910 1.00 23.25 ? 740 LEU A CD2 1 ATOM 5915 N N . GLY A 1 741 ? 21.230 86.612 -25.542 1.00 26.39 ? 741 GLY A N 1 ATOM 5916 C CA . GLY A 1 741 ? 21.328 87.921 -26.180 1.00 26.57 ? 741 GLY A CA 1 ATOM 5917 C C . GLY A 1 741 ? 21.932 87.706 -27.567 1.00 24.95 ? 741 GLY A C 1 ATOM 5918 O O . GLY A 1 741 ? 21.651 86.707 -28.219 1.00 26.42 ? 741 GLY A O 1 ATOM 5919 N N . GLN A 1 742 ? 22.750 88.637 -28.037 1.00 26.43 ? 742 GLN A N 1 ATOM 5920 C CA . GLN A 1 742 ? 23.398 88.443 -29.345 1.00 27.69 ? 742 GLN A CA 1 ATOM 5921 C C . GLN A 1 742 ? 24.902 88.429 -29.012 1.00 25.41 ? 742 GLN A C 1 ATOM 5922 O O . GLN A 1 742 ? 25.596 89.429 -29.109 1.00 26.34 ? 742 GLN A O 1 ATOM 5923 C CB . GLN A 1 742 ? 23.048 89.599 -30.289 1.00 32.33 ? 742 GLN A CB 1 ATOM 5924 C CG . GLN A 1 742 ? 23.477 89.370 -31.737 1.00 39.71 ? 742 GLN A CG 1 ATOM 5925 C CD . GLN A 1 742 ? 22.762 90.307 -32.734 1.00 44.92 ? 742 GLN A CD 1 ATOM 5926 O OE1 . GLN A 1 742 ? 22.931 90.172 -33.950 1.00 46.15 ? 742 GLN A OE1 1 ATOM 5927 N NE2 . GLN A 1 742 ? 21.956 91.255 -32.215 1.00 47.02 ? 742 GLN A NE2 1 ATOM 5928 N N . PRO A 1 743 ? 25.423 87.262 -28.623 1.00 22.95 ? 743 PRO A N 1 ATOM 5929 C CA . PRO A 1 743 ? 26.844 87.215 -28.268 1.00 22.16 ? 743 PRO A CA 1 ATOM 5930 C C . PRO A 1 743 ? 27.886 87.433 -29.364 1.00 20.64 ? 743 PRO A C 1 ATOM 5931 O O . PRO A 1 743 ? 27.659 87.182 -30.562 1.00 23.22 ? 743 PRO A O 1 ATOM 5932 C CB . PRO A 1 743 ? 26.979 85.842 -27.599 1.00 20.49 ? 743 PRO A CB 1 ATOM 5933 C CG . PRO A 1 743 ? 26.014 85.006 -28.311 1.00 20.52 ? 743 PRO A CG 1 ATOM 5934 C CD . PRO A 1 743 ? 24.826 85.913 -28.696 1.00 20.59 ? 743 PRO A CD 1 ATOM 5935 N N . VAL A 1 744 ? 29.053 87.914 -28.943 1.00 18.01 ? 744 VAL A N 1 ATOM 5936 C CA . VAL A 1 744 ? 30.140 88.118 -29.901 1.00 17.70 ? 744 VAL A CA 1 ATOM 5937 C C . VAL A 1 744 ? 30.859 86.780 -30.136 1.00 18.43 ? 744 VAL A C 1 ATOM 5938 O O . VAL A 1 744 ? 31.220 86.084 -29.173 1.00 19.07 ? 744 VAL A O 1 ATOM 5939 C CB . VAL A 1 744 ? 31.118 89.152 -29.358 1.00 16.42 ? 744 VAL A CB 1 ATOM 5940 C CG1 . VAL A 1 744 ? 32.274 89.307 -30.302 1.00 17.19 ? 744 VAL A CG1 1 ATOM 5941 C CG2 . VAL A 1 744 ? 30.382 90.525 -29.148 1.00 19.60 ? 744 VAL A CG2 1 ATOM 5942 N N . VAL A 1 745 ? 31.036 86.410 -31.391 1.00 17.49 ? 745 VAL A N 1 ATOM 5943 C CA . VAL A 1 745 ? 31.668 85.165 -31.779 1.00 15.90 ? 745 VAL A CA 1 ATOM 5944 C C . VAL A 1 745 ? 32.960 85.394 -32.535 1.00 17.34 ? 745 VAL A C 1 ATOM 5945 O O . VAL A 1 745 ? 33.005 86.166 -33.485 1.00 17.23 ? 745 VAL A O 1 ATOM 5946 C CB . VAL A 1 745 ? 30.704 84.310 -32.663 1.00 15.54 ? 745 VAL A CB 1 ATOM 5947 C CG1 . VAL A 1 745 ? 31.398 82.977 -33.078 1.00 17.20 ? 745 VAL A CG1 1 ATOM 5948 C CG2 . VAL A 1 745 ? 29.423 84.070 -31.914 1.00 15.88 ? 745 VAL A CG2 1 ATOM 5949 N N . LEU A 1 746 ? 34.040 84.727 -32.140 1.00 15.05 ? 746 LEU A N 1 ATOM 5950 C CA . LEU A 1 746 ? 35.341 84.853 -32.768 1.00 13.87 ? 746 LEU A CA 1 ATOM 5951 C C . LEU A 1 746 ? 35.774 83.553 -33.412 1.00 14.92 ? 746 LEU A C 1 ATOM 5952 O O . LEU A 1 746 ? 35.862 82.514 -32.725 1.00 15.20 ? 746 LEU A O 1 ATOM 5953 C CB . LEU A 1 746 ? 36.377 85.274 -31.725 1.00 15.89 ? 746 LEU A CB 1 ATOM 5954 C CG . LEU A 1 746 ? 37.833 85.252 -32.199 1.00 17.43 ? 746 LEU A CG 1 ATOM 5955 C CD1 . LEU A 1 746 ? 38.068 86.326 -33.220 1.00 19.26 ? 746 LEU A CD1 1 ATOM 5956 C CD2 . LEU A 1 746 ? 38.750 85.479 -30.988 1.00 19.79 ? 746 LEU A CD2 1 ATOM 5957 N N . VAL A 1 747 ? 36.099 83.577 -34.701 1.00 15.35 ? 747 VAL A N 1 ATOM 5958 C CA . VAL A 1 747 ? 36.480 82.384 -35.417 1.00 14.57 ? 747 VAL A CA 1 ATOM 5959 C C . VAL A 1 747 ? 37.910 82.539 -35.848 1.00 17.20 ? 747 VAL A C 1 ATOM 5960 O O . VAL A 1 747 ? 38.258 83.508 -36.521 1.00 17.91 ? 747 VAL A O 1 ATOM 5961 C CB . VAL A 1 747 ? 35.562 82.170 -36.668 1.00 14.80 ? 747 VAL A CB 1 ATOM 5962 C CG1 . VAL A 1 747 ? 35.928 80.893 -37.344 1.00 16.56 ? 747 VAL A CG1 1 ATOM 5963 C CG2 . VAL A 1 747 ? 34.102 82.169 -36.265 1.00 16.34 ? 747 VAL A CG2 1 ATOM 5964 N N . THR A 1 748 ? 38.780 81.613 -35.468 1.00 16.11 ? 748 THR A N 1 ATOM 5965 C CA . THR A 1 748 ? 40.173 81.644 -35.884 1.00 16.39 ? 748 THR A CA 1 ATOM 5966 C C . THR A 1 748 ? 40.366 80.400 -36.693 1.00 17.79 ? 748 THR A C 1 ATOM 5967 O O . THR A 1 748 ? 40.056 79.304 -36.220 1.00 17.89 ? 748 THR A O 1 ATOM 5968 C CB . THR A 1 748 ? 41.116 81.664 -34.647 1.00 18.49 ? 748 THR A CB 1 ATOM 5969 O OG1 . THR A 1 748 ? 40.871 82.857 -33.893 1.00 19.60 ? 748 THR A OG1 1 ATOM 5970 C CG2 . THR A 1 748 ? 42.609 81.606 -35.079 1.00 19.33 ? 748 THR A CG2 1 ATOM 5971 N N . LYS A 1 749 ? 40.858 80.537 -37.925 1.00 16.64 ? 749 LYS A N 1 ATOM 5972 C CA . LYS A 1 749 ? 41.019 79.398 -38.808 1.00 18.07 ? 749 LYS A CA 1 ATOM 5973 C C . LYS A 1 749 ? 42.447 79.268 -39.248 1.00 17.90 ? 749 LYS A C 1 ATOM 5974 O O . LYS A 1 749 ? 43.050 80.195 -39.841 1.00 17.75 ? 749 LYS A O 1 ATOM 5975 C CB . LYS A 1 749 ? 40.110 79.576 -40.029 1.00 18.18 ? 749 LYS A CB 1 ATOM 5976 C CG . LYS A 1 749 ? 40.251 78.451 -41.042 1.00 23.20 ? 749 LYS A CG 1 ATOM 5977 C CD . LYS A 1 749 ? 39.333 78.756 -42.238 1.00 27.18 ? 749 LYS A CD 1 ATOM 5978 C CE . LYS A 1 749 ? 39.590 77.783 -43.366 1.00 33.08 ? 749 LYS A CE 1 ATOM 5979 N NZ . LYS A 1 749 ? 39.120 78.421 -44.642 1.00 38.17 ? 749 LYS A NZ 1 ATOM 5980 N N . GLY A 1 750 ? 43.028 78.143 -38.885 1.00 16.39 ? 750 GLY A N 1 ATOM 5981 C CA . GLY A 1 750 ? 44.405 77.880 -39.233 1.00 17.95 ? 750 GLY A CA 1 ATOM 5982 C C . GLY A 1 750 ? 44.576 76.498 -39.792 1.00 18.44 ? 750 GLY A C 1 ATOM 5983 O O . GLY A 1 750 ? 43.670 75.645 -39.692 1.00 19.55 ? 750 GLY A O 1 ATOM 5984 N N . LYS A 1 751 ? 45.749 76.282 -40.365 1.00 18.98 ? 751 LYS A N 1 ATOM 5985 C CA . LYS A 1 751 ? 46.061 75.001 -40.938 1.00 20.36 ? 751 LYS A CA 1 ATOM 5986 C C . LYS A 1 751 ? 46.191 73.900 -39.884 1.00 18.62 ? 751 LYS A C 1 ATOM 5987 O O . LYS A 1 751 ? 45.807 72.756 -40.127 1.00 19.57 ? 751 LYS A O 1 ATOM 5988 C CB . LYS A 1 751 ? 47.368 75.103 -41.716 1.00 23.54 ? 751 LYS A CB 1 ATOM 5989 C CG . LYS A 1 751 ? 47.751 73.781 -42.332 1.00 34.34 ? 751 LYS A CG 1 ATOM 5990 C CD . LYS A 1 751 ? 49.079 73.873 -43.093 1.00 41.06 ? 751 LYS A CD 1 ATOM 5991 C CE . LYS A 1 751 ? 49.337 72.576 -43.843 1.00 44.27 ? 751 LYS A CE 1 ATOM 5992 N NZ . LYS A 1 751 ? 48.214 72.321 -44.813 1.00 48.36 ? 751 LYS A NZ 1 ATOM 5993 N N . LEU A 1 752 ? 46.763 74.245 -38.735 1.00 18.65 ? 752 LEU A N 1 ATOM 5994 C CA . LEU A 1 752 ? 46.989 73.272 -37.656 1.00 17.04 ? 752 LEU A CA 1 ATOM 5995 C C . LEU A 1 752 ? 45.913 73.314 -36.576 1.00 17.57 ? 752 LEU A C 1 ATOM 5996 O O . LEU A 1 752 ? 45.605 72.276 -35.983 1.00 17.16 ? 752 LEU A O 1 ATOM 5997 C CB . LEU A 1 752 ? 48.334 73.533 -36.974 1.00 17.33 ? 752 LEU A CB 1 ATOM 5998 C CG . LEU A 1 752 ? 49.560 73.471 -37.911 1.00 19.14 ? 752 LEU A CG 1 ATOM 5999 C CD1 . LEU A 1 752 ? 50.833 73.591 -37.075 1.00 21.53 ? 752 LEU A CD1 1 ATOM 6000 C CD2 . LEU A 1 752 ? 49.561 72.186 -38.714 1.00 22.99 ? 752 LEU A CD2 1 ATOM 6001 N N . GLU A 1 753 ? 45.331 74.493 -36.337 1.00 16.53 ? 753 GLU A N 1 ATOM 6002 C CA . GLU A 1 753 ? 44.368 74.625 -35.270 1.00 16.07 ? 753 GLU A CA 1 ATOM 6003 C C . GLU A 1 753 ? 43.371 75.726 -35.592 1.00 16.10 ? 753 GLU A C 1 ATOM 6004 O O . GLU A 1 753 ? 43.795 76.837 -35.998 1.00 17.94 ? 753 GLU A O 1 ATOM 6005 C CB . GLU A 1 753 ? 45.105 74.997 -33.971 1.00 15.22 ? 753 GLU A CB 1 ATOM 6006 C CG . GLU A 1 753 ? 44.167 75.264 -32.785 1.00 18.41 ? 753 GLU A CG 1 ATOM 6007 C CD . GLU A 1 753 ? 44.916 75.810 -31.538 1.00 21.44 ? 753 GLU A CD 1 ATOM 6008 O OE1 . GLU A 1 753 ? 45.256 77.025 -31.501 1.00 28.58 ? 753 GLU A OE1 1 ATOM 6009 O OE2 . GLU A 1 753 ? 45.157 74.999 -30.631 1.00 28.46 ? 753 GLU A OE2 1 ATOM 6010 N N . SER A 1 754 ? 42.095 75.441 -35.399 1.00 14.22 ? 754 SER A N 1 ATOM 6011 C CA . SER A 1 754 ? 41.045 76.426 -35.591 1.00 15.50 ? 754 SER A CA 1 ATOM 6012 C C . SER A 1 754 ? 40.150 76.424 -34.375 1.00 15.60 ? 754 SER A C 1 ATOM 6013 O O . SER A 1 754 ? 40.140 75.455 -33.566 1.00 16.61 ? 754 SER A O 1 ATOM 6014 C CB . SER A 1 754 ? 40.211 76.072 -36.824 1.00 16.38 ? 754 SER A CB 1 ATOM 6015 O OG . SER A 1 754 ? 41.000 76.127 -38.002 1.00 16.98 ? 754 SER A OG 1 ATOM 6016 N N . SER A 1 755 ? 39.405 77.501 -34.202 1.00 14.43 ? 755 SER A N 1 ATOM 6017 C CA . SER A 1 755 ? 38.520 77.570 -33.060 1.00 15.45 ? 755 SER A CA 1 ATOM 6018 C C . SER A 1 755 ? 37.345 78.505 -33.239 1.00 15.54 ? 755 SER A C 1 ATOM 6019 O O . SER A 1 755 ? 37.372 79.383 -34.099 1.00 15.74 ? 755 SER A O 1 ATOM 6020 C CB A SER A 1 755 ? 39.324 78.007 -31.832 0.50 16.41 ? 755 SER A CB 1 ATOM 6021 C CB B SER A 1 755 ? 39.242 77.772 -31.742 0.50 18.61 ? 755 SER A CB 1 ATOM 6022 O OG A SER A 1 755 ? 39.989 79.241 -32.052 0.50 17.17 ? 755 SER A OG 1 ATOM 6023 O OG B SER A 1 755 ? 39.537 79.145 -31.605 0.50 20.24 ? 755 SER A OG 1 ATOM 6024 N N . VAL A 1 756 ? 36.302 78.303 -32.447 1.00 13.91 ? 756 VAL A N 1 ATOM 6025 C CA . VAL A 1 756 ? 35.160 79.183 -32.424 1.00 13.53 ? 756 VAL A CA 1 ATOM 6026 C C . VAL A 1 756 ? 35.002 79.506 -30.933 1.00 14.24 ? 756 VAL A C 1 ATOM 6027 O O . VAL A 1 756 ? 34.806 78.586 -30.087 1.00 15.80 ? 756 VAL A O 1 ATOM 6028 C CB . VAL A 1 756 ? 33.867 78.533 -32.951 1.00 14.38 ? 756 VAL A CB 1 ATOM 6029 C CG1 . VAL A 1 756 ? 32.655 79.508 -32.693 1.00 16.27 ? 756 VAL A CG1 1 ATOM 6030 C CG2 . VAL A 1 756 ? 34.060 78.171 -34.441 1.00 17.12 ? 756 VAL A CG2 1 ATOM 6031 N N . SER A 1 757 ? 35.063 80.783 -30.589 1.00 13.92 ? 757 SER A N 1 ATOM 6032 C CA . SER A 1 757 ? 34.927 81.202 -29.198 1.00 14.19 ? 757 SER A CA 1 ATOM 6033 C C . SER A 1 757 ? 33.772 82.162 -29.078 1.00 15.29 ? 757 SER A C 1 ATOM 6034 O O . SER A 1 757 ? 33.592 82.993 -29.968 1.00 17.76 ? 757 SER A O 1 ATOM 6035 C CB . SER A 1 757 ? 36.224 81.905 -28.709 1.00 15.68 ? 757 SER A CB 1 ATOM 6036 O OG . SER A 1 757 ? 37.312 81.010 -28.893 1.00 19.96 ? 757 SER A OG 1 ATOM 6037 N N . VAL A 1 758 ? 33.006 82.112 -27.999 1.00 14.03 ? 758 VAL A N 1 ATOM 6038 C CA . VAL A 1 758 ? 31.877 83.018 -27.840 1.00 16.27 ? 758 VAL A CA 1 ATOM 6039 C C . VAL A 1 758 ? 31.745 83.452 -26.403 1.00 15.81 ? 758 VAL A C 1 ATOM 6040 O O . VAL A 1 758 ? 31.945 82.669 -25.474 1.00 15.96 ? 758 VAL A O 1 ATOM 6041 C CB . VAL A 1 758 ? 30.557 82.386 -28.373 1.00 16.70 ? 758 VAL A CB 1 ATOM 6042 C CG1 . VAL A 1 758 ? 30.277 81.050 -27.677 1.00 17.89 ? 758 VAL A CG1 1 ATOM 6043 C CG2 . VAL A 1 758 ? 29.400 83.350 -28.148 1.00 17.51 ? 758 VAL A CG2 1 ATOM 6044 N N . GLY A 1 759 ? 31.448 84.727 -26.213 1.00 16.03 ? 759 GLY A N 1 ATOM 6045 C CA . GLY A 1 759 ? 31.328 85.314 -24.890 1.00 17.04 ? 759 GLY A CA 1 ATOM 6046 C C . GLY A 1 759 ? 29.891 85.283 -24.420 1.00 18.43 ? 759 GLY A C 1 ATOM 6047 O O . GLY A 1 759 ? 29.085 86.159 -24.739 1.00 18.28 ? 759 GLY A O 1 ATOM 6048 N N . LEU A 1 760 ? 29.534 84.244 -23.678 1.00 17.39 ? 760 LEU A N 1 ATOM 6049 C CA . LEU A 1 760 ? 28.174 84.109 -23.177 1.00 17.96 ? 760 LEU A CA 1 ATOM 6050 C C . LEU A 1 760 ? 28.084 84.602 -21.765 1.00 17.02 ? 760 LEU A C 1 ATOM 6051 O O . LEU A 1 760 ? 29.102 84.770 -21.095 1.00 20.23 ? 760 LEU A O 1 ATOM 6052 C CB . LEU A 1 760 ? 27.788 82.622 -23.164 1.00 16.55 ? 760 LEU A CB 1 ATOM 6053 C CG . LEU A 1 760 ? 28.003 81.928 -24.501 1.00 17.98 ? 760 LEU A CG 1 ATOM 6054 C CD1 . LEU A 1 760 ? 27.655 80.418 -24.396 1.00 21.38 ? 760 LEU A CD1 1 ATOM 6055 C CD2 . LEU A 1 760 ? 27.075 82.579 -25.554 1.00 19.98 ? 760 LEU A CD2 1 ATOM 6056 N N . PRO A 1 761 ? 26.864 84.828 -21.255 1.00 20.44 ? 761 PRO A N 1 ATOM 6057 C CA . PRO A 1 761 ? 26.815 85.292 -19.857 1.00 20.24 ? 761 PRO A CA 1 ATOM 6058 C C . PRO A 1 761 ? 27.391 84.172 -18.954 1.00 20.54 ? 761 PRO A C 1 ATOM 6059 O O . PRO A 1 761 ? 26.941 83.008 -19.010 1.00 19.93 ? 761 PRO A O 1 ATOM 6060 C CB . PRO A 1 761 ? 25.311 85.526 -19.611 1.00 22.83 ? 761 PRO A CB 1 ATOM 6061 C CG . PRO A 1 761 ? 24.822 85.883 -21.001 1.00 21.92 ? 761 PRO A CG 1 ATOM 6062 C CD . PRO A 1 761 ? 25.552 84.925 -21.915 1.00 20.95 ? 761 PRO A CD 1 ATOM 6063 N N . SER A 1 762 ? 28.376 84.564 -18.139 1.00 19.81 ? 762 SER A N 1 ATOM 6064 C CA . SER A 1 762 ? 29.084 83.689 -17.210 1.00 18.10 ? 762 SER A CA 1 ATOM 6065 C C . SER A 1 762 ? 30.028 82.684 -17.836 1.00 16.76 ? 762 SER A C 1 ATOM 6066 O O . SER A 1 762 ? 30.714 81.991 -17.105 1.00 16.63 ? 762 SER A O 1 ATOM 6067 C CB . SER A 1 762 ? 28.107 82.888 -16.354 1.00 18.71 ? 762 SER A CB 1 ATOM 6068 O OG . SER A 1 762 ? 27.271 83.703 -15.539 1.00 21.74 ? 762 SER A OG 1 ATOM 6069 N N . VAL A 1 763 ? 30.108 82.610 -19.156 1.00 15.62 ? 763 VAL A N 1 ATOM 6070 C CA . VAL A 1 763 ? 30.973 81.610 -19.774 1.00 14.05 ? 763 VAL A CA 1 ATOM 6071 C C . VAL A 1 763 ? 31.576 82.018 -21.089 1.00 17.88 ? 763 VAL A C 1 ATOM 6072 O O . VAL A 1 763 ? 30.847 82.389 -21.974 1.00 17.16 ? 763 VAL A O 1 ATOM 6073 C CB . VAL A 1 763 ? 30.199 80.282 -20.075 1.00 17.00 ? 763 VAL A CB 1 ATOM 6074 C CG1 . VAL A 1 763 ? 31.174 79.215 -20.613 1.00 17.94 ? 763 VAL A CG1 1 ATOM 6075 C CG2 . VAL A 1 763 ? 29.484 79.758 -18.835 1.00 20.38 ? 763 VAL A CG2 1 ATOM 6076 N N . VAL A 1 764 ? 32.889 82.014 -21.199 1.00 13.55 ? 764 VAL A N 1 ATOM 6077 C CA . VAL A 1 764 ? 33.499 82.195 -22.503 1.00 13.82 ? 764 VAL A CA 1 ATOM 6078 C C . VAL A 1 764 ? 33.652 80.735 -22.950 1.00 13.75 ? 764 VAL A C 1 ATOM 6079 O O . VAL A 1 764 ? 34.466 79.971 -22.374 1.00 13.77 ? 764 VAL A O 1 ATOM 6080 C CB . VAL A 1 764 ? 34.867 82.903 -22.478 1.00 15.24 ? 764 VAL A CB 1 ATOM 6081 C CG1 . VAL A 1 764 ? 35.407 82.947 -23.945 1.00 15.68 ? 764 VAL A CG1 1 ATOM 6082 C CG2 . VAL A 1 764 ? 34.709 84.331 -21.908 1.00 17.26 ? 764 VAL A CG2 1 ATOM 6083 N N . HIS A 1 765 ? 32.883 80.334 -23.971 1.00 13.78 ? 765 HIS A N 1 ATOM 6084 C CA . HIS A 1 765 ? 32.829 78.954 -24.473 1.00 12.94 ? 765 HIS A CA 1 ATOM 6085 C C . HIS A 1 765 ? 33.674 78.868 -25.740 1.00 16.27 ? 765 HIS A C 1 ATOM 6086 O O . HIS A 1 765 ? 33.516 79.688 -26.643 1.00 15.44 ? 765 HIS A O 1 ATOM 6087 C CB . HIS A 1 765 ? 31.353 78.621 -24.757 1.00 14.04 ? 765 HIS A CB 1 ATOM 6088 C CG . HIS A 1 765 ? 31.123 77.262 -25.298 1.00 13.63 ? 765 HIS A CG 1 ATOM 6089 N ND1 . HIS A 1 765 ? 30.609 77.006 -26.556 1.00 17.09 ? 765 HIS A ND1 1 ATOM 6090 C CD2 . HIS A 1 765 ? 31.322 76.059 -24.717 1.00 10.63 ? 765 HIS A CD2 1 ATOM 6091 C CE1 . HIS A 1 765 ? 30.505 75.701 -26.735 1.00 13.10 ? 765 HIS A CE1 1 ATOM 6092 N NE2 . HIS A 1 765 ? 30.938 75.099 -25.629 1.00 16.75 ? 765 HIS A NE2 1 ATOM 6093 N N . GLN A 1 766 ? 34.548 77.879 -25.818 1.00 13.63 ? 766 GLN A N 1 ATOM 6094 C CA . GLN A 1 766 ? 35.459 77.715 -26.941 1.00 14.44 ? 766 GLN A CA 1 ATOM 6095 C C . GLN A 1 766 ? 35.484 76.278 -27.443 1.00 14.09 ? 766 GLN A C 1 ATOM 6096 O O . GLN A 1 766 ? 35.572 75.334 -26.640 1.00 14.68 ? 766 GLN A O 1 ATOM 6097 C CB . GLN A 1 766 ? 36.887 78.110 -26.502 1.00 15.97 ? 766 GLN A CB 1 ATOM 6098 C CG A GLN A 1 766 ? 36.981 79.421 -25.694 0.50 16.83 ? 766 GLN A CG 1 ATOM 6099 C CG B GLN A 1 766 ? 37.868 78.066 -27.754 0.50 14.11 ? 766 GLN A CG 1 ATOM 6100 C CD A GLN A 1 766 ? 38.030 79.372 -24.547 0.50 21.74 ? 766 GLN A CD 1 ATOM 6101 C CD B GLN A 1 766 ? 39.252 78.610 -27.399 0.50 18.05 ? 766 GLN A CD 1 ATOM 6102 O OE1 A GLN A 1 766 ? 39.207 79.096 -24.791 0.50 19.94 ? 766 GLN A OE1 1 ATOM 6103 O OE1 B GLN A 1 766 ? 40.040 78.988 -28.287 0.50 18.13 ? 766 GLN A OE1 1 ATOM 6104 N NE2 A GLN A 1 766 ? 37.591 79.637 -23.295 0.50 18.94 ? 766 GLN A NE2 1 ATOM 6105 N NE2 B GLN A 1 766 ? 39.555 78.649 -26.100 0.50 17.26 ? 766 GLN A NE2 1 ATOM 6106 N N . THR A 1 767 ? 35.408 76.099 -28.761 1.00 13.57 ? 767 THR A N 1 ATOM 6107 C CA . THR A 1 767 ? 35.504 74.807 -29.375 1.00 13.36 ? 767 THR A CA 1 ATOM 6108 C C . THR A 1 767 ? 36.768 74.886 -30.210 1.00 15.15 ? 767 THR A C 1 ATOM 6109 O O . THR A 1 767 ? 36.870 75.744 -31.113 1.00 14.96 ? 767 THR A O 1 ATOM 6110 C CB . THR A 1 767 ? 34.328 74.534 -30.290 1.00 13.33 ? 767 THR A CB 1 ATOM 6111 O OG1 . THR A 1 767 ? 33.133 74.638 -29.518 1.00 16.31 ? 767 THR A OG1 1 ATOM 6112 C CG2 . THR A 1 767 ? 34.444 73.119 -30.894 1.00 14.55 ? 767 THR A CG2 1 ATOM 6113 N N . ILE A 1 768 ? 37.730 74.017 -29.943 1.00 15.03 ? 768 ILE A N 1 ATOM 6114 C CA . ILE A 1 768 ? 39.015 73.976 -30.634 1.00 13.71 ? 768 ILE A CA 1 ATOM 6115 C C . ILE A 1 768 ? 39.156 72.713 -31.450 1.00 15.01 ? 768 ILE A C 1 ATOM 6116 O O . ILE A 1 768 ? 38.820 71.620 -30.987 1.00 16.38 ? 768 ILE A O 1 ATOM 6117 C CB . ILE A 1 768 ? 40.184 74.075 -29.625 1.00 12.55 ? 768 ILE A CB 1 ATOM 6118 C CG1 . ILE A 1 768 ? 39.964 75.292 -28.777 1.00 15.31 ? 768 ILE A CG1 1 ATOM 6119 C CG2 . ILE A 1 768 ? 41.529 74.140 -30.352 1.00 16.56 ? 768 ILE A CG2 1 ATOM 6120 C CD1 . ILE A 1 768 ? 40.767 75.274 -27.476 1.00 18.75 ? 768 ILE A CD1 1 ATOM 6121 N N . MET A 1 769 ? 39.698 72.872 -32.652 1.00 15.42 ? 769 MET A N 1 ATOM 6122 C CA . MET A 1 769 ? 39.862 71.765 -33.574 1.00 17.04 ? 769 MET A CA 1 ATOM 6123 C C . MET A 1 769 ? 41.289 71.638 -34.007 1.00 17.91 ? 769 MET A C 1 ATOM 6124 O O . MET A 1 769 ? 41.906 72.610 -34.461 1.00 16.96 ? 769 MET A O 1 ATOM 6125 C CB . MET A 1 769 ? 38.985 72.002 -34.796 1.00 18.56 ? 769 MET A CB 1 ATOM 6126 C CG A MET A 1 769 ? 37.539 72.121 -34.438 0.50 17.62 ? 769 MET A CG 1 ATOM 6127 C CG B MET A 1 769 ? 37.333 71.878 -34.485 0.50 19.95 ? 769 MET A CG 1 ATOM 6128 S SD A MET A 1 769 ? 36.582 72.545 -35.889 0.50 18.84 ? 769 MET A SD 1 ATOM 6129 S SD B MET A 1 769 ? 36.333 72.884 -35.643 0.50 20.79 ? 769 MET A SD 1 ATOM 6130 C CE A MET A 1 769 ? 36.898 71.154 -36.933 0.50 16.19 ? 769 MET A CE 1 ATOM 6131 C CE B MET A 1 769 ? 36.546 74.503 -34.865 0.50 21.99 ? 769 MET A CE 1 ATOM 6132 N N . ARG A 1 770 ? 41.836 70.444 -33.831 1.00 16.93 ? 770 ARG A N 1 ATOM 6133 C CA . ARG A 1 770 ? 43.198 70.206 -34.224 1.00 18.49 ? 770 ARG A CA 1 ATOM 6134 C C . ARG A 1 770 ? 43.285 69.033 -35.197 1.00 20.79 ? 770 ARG A C 1 ATOM 6135 O O . ARG A 1 770 ? 44.380 68.523 -35.443 1.00 21.91 ? 770 ARG A O 1 ATOM 6136 C CB . ARG A 1 770 ? 44.072 70.002 -32.976 1.00 20.10 ? 770 ARG A CB 1 ATOM 6137 C CG A ARG A 1 770 ? 43.858 71.077 -31.891 0.50 20.56 ? 770 ARG A CG 1 ATOM 6138 C CG B ARG A 1 770 ? 44.423 71.045 -32.249 0.50 19.05 ? 770 ARG A CG 1 ATOM 6139 C CD A ARG A 1 770 ? 44.956 71.087 -30.799 0.50 18.76 ? 770 ARG A CD 1 ATOM 6140 C CD B ARG A 1 770 ? 45.312 70.568 -31.113 0.50 19.38 ? 770 ARG A CD 1 ATOM 6141 N NE A ARG A 1 770 ? 44.768 72.128 -29.783 0.50 21.13 ? 770 ARG A NE 1 ATOM 6142 N NE B ARG A 1 770 ? 44.626 69.526 -30.354 0.50 21.01 ? 770 ARG A NE 1 ATOM 6143 C CZ A ARG A 1 770 ? 44.040 71.992 -28.676 0.50 19.09 ? 770 ARG A CZ 1 ATOM 6144 C CZ B ARG A 1 770 ? 43.801 69.765 -29.340 0.50 21.02 ? 770 ARG A CZ 1 ATOM 6145 N NH1 A ARG A 1 770 ? 43.417 70.852 -28.420 0.50 21.53 ? 770 ARG A NH1 1 ATOM 6146 N NH1 B ARG A 1 770 ? 43.562 71.012 -28.946 0.50 22.42 ? 770 ARG A NH1 1 ATOM 6147 N NH2 A ARG A 1 770 ? 43.933 72.997 -27.820 0.50 19.45 ? 770 ARG A NH2 1 ATOM 6148 N NH2 B ARG A 1 770 ? 43.198 68.753 -28.735 0.50 19.87 ? 770 ARG A NH2 1 ATOM 6149 N N . GLY A 1 771 ? 42.133 68.605 -35.727 1.00 19.17 ? 771 GLY A N 1 ATOM 6150 C CA . GLY A 1 771 ? 42.130 67.530 -36.701 1.00 22.57 ? 771 GLY A CA 1 ATOM 6151 C C . GLY A 1 771 ? 41.479 66.243 -36.280 1.00 25.27 ? 771 GLY A C 1 ATOM 6152 O O . GLY A 1 771 ? 41.302 65.344 -37.129 1.00 26.93 ? 771 GLY A O 1 ATOM 6153 N N . GLY A 1 772 ? 41.156 66.145 -34.987 1.00 24.01 ? 772 GLY A N 1 ATOM 6154 C CA . GLY A 1 772 ? 40.490 64.966 -34.428 1.00 23.68 ? 772 GLY A CA 1 ATOM 6155 C C . GLY A 1 772 ? 39.316 65.399 -33.556 1.00 21.34 ? 772 GLY A C 1 ATOM 6156 O O . GLY A 1 772 ? 38.609 66.347 -33.888 1.00 21.76 ? 772 GLY A O 1 ATOM 6157 N N . ALA A 1 773 ? 39.077 64.706 -32.440 1.00 18.97 ? 773 ALA A N 1 ATOM 6158 C CA . ALA A 1 773 ? 37.975 65.076 -31.566 1.00 17.51 ? 773 ALA A CA 1 ATOM 6159 C C . ALA A 1 773 ? 38.185 66.514 -31.087 1.00 15.41 ? 773 ALA A C 1 ATOM 6160 O O . ALA A 1 773 ? 39.287 66.885 -30.663 1.00 17.12 ? 773 ALA A O 1 ATOM 6161 C CB . ALA A 1 773 ? 37.914 64.137 -30.376 1.00 19.02 ? 773 ALA A CB 1 ATOM 6162 N N . PRO A 1 774 ? 37.137 67.329 -31.130 1.00 16.16 ? 774 PRO A N 1 ATOM 6163 C CA . PRO A 1 774 ? 37.358 68.697 -30.661 1.00 14.73 ? 774 PRO A CA 1 ATOM 6164 C C . PRO A 1 774 ? 37.626 68.763 -29.170 1.00 14.80 ? 774 PRO A C 1 ATOM 6165 O O . PRO A 1 774 ? 37.360 67.812 -28.419 1.00 14.30 ? 774 PRO A O 1 ATOM 6166 C CB . PRO A 1 774 ? 36.059 69.430 -31.006 1.00 17.19 ? 774 PRO A CB 1 ATOM 6167 C CG . PRO A 1 774 ? 35.039 68.354 -31.140 1.00 21.49 ? 774 PRO A CG 1 ATOM 6168 C CD . PRO A 1 774 ? 35.796 67.152 -31.710 1.00 15.79 ? 774 PRO A CD 1 ATOM 6169 N N . GLU A 1 775 ? 38.187 69.891 -28.801 1.00 14.17 ? 775 GLU A N 1 ATOM 6170 C CA . GLU A 1 775 ? 38.457 70.237 -27.408 1.00 12.26 ? 775 GLU A CA 1 ATOM 6171 C C . GLU A 1 775 ? 37.529 71.382 -27.049 1.00 13.59 ? 775 GLU A C 1 ATOM 6172 O O . GLU A 1 775 ? 37.324 72.307 -27.859 1.00 15.48 ? 775 GLU A O 1 ATOM 6173 C CB . GLU A 1 775 ? 39.884 70.674 -27.216 1.00 13.02 ? 775 GLU A CB 1 ATOM 6174 C CG . GLU A 1 775 ? 40.192 71.107 -25.765 1.00 14.71 ? 775 GLU A CG 1 ATOM 6175 C CD . GLU A 1 775 ? 41.659 71.326 -25.524 1.00 22.73 ? 775 GLU A CD 1 ATOM 6176 O OE1 . GLU A 1 775 ? 42.469 70.508 -25.999 1.00 26.13 ? 775 GLU A OE1 1 ATOM 6177 O OE2 . GLU A 1 775 ? 42.021 72.294 -24.833 1.00 25.28 ? 775 GLU A OE2 1 ATOM 6178 N N . ILE A 1 776 ? 36.903 71.324 -25.896 1.00 12.54 ? 776 ILE A N 1 ATOM 6179 C CA . ILE A 1 776 ? 36.021 72.376 -25.448 1.00 12.79 ? 776 ILE A CA 1 ATOM 6180 C C . ILE A 1 776 ? 36.654 73.013 -24.228 1.00 13.99 ? 776 ILE A C 1 ATOM 6181 O O . ILE A 1 776 ? 37.154 72.302 -23.336 1.00 14.29 ? 776 ILE A O 1 ATOM 6182 C CB . ILE A 1 776 ? 34.636 71.838 -25.015 1.00 14.80 ? 776 ILE A CB 1 ATOM 6183 C CG1 . ILE A 1 776 ? 34.067 70.894 -26.091 1.00 17.86 ? 776 ILE A CG1 1 ATOM 6184 C CG2 . ILE A 1 776 ? 33.734 73.015 -24.620 1.00 15.50 ? 776 ILE A CG2 1 ATOM 6185 C CD1 . ILE A 1 776 ? 33.904 71.483 -27.477 1.00 20.77 ? 776 ILE A CD1 1 ATOM 6186 N N . ARG A 1 777 ? 36.685 74.336 -24.183 1.00 13.90 ? 777 ARG A N 1 ATOM 6187 C CA . ARG A 1 777 ? 37.187 75.039 -22.997 1.00 12.76 ? 777 ARG A CA 1 ATOM 6188 C C . ARG A 1 777 ? 36.143 76.050 -22.581 1.00 14.33 ? 777 ARG A C 1 ATOM 6189 O O . ARG A 1 777 ? 35.624 76.830 -23.423 1.00 14.43 ? 777 ARG A O 1 ATOM 6190 C CB . ARG A 1 777 ? 38.496 75.800 -23.261 1.00 14.40 ? 777 ARG A CB 1 ATOM 6191 C CG . ARG A 1 777 ? 39.629 74.908 -23.604 1.00 15.02 ? 777 ARG A CG 1 ATOM 6192 C CD . ARG A 1 777 ? 40.915 75.717 -23.720 1.00 16.50 ? 777 ARG A CD 1 ATOM 6193 N NE . ARG A 1 777 ? 42.009 74.880 -24.173 1.00 17.46 ? 777 ARG A NE 1 ATOM 6194 C CZ . ARG A 1 777 ? 43.208 75.355 -24.479 1.00 23.21 ? 777 ARG A CZ 1 ATOM 6195 N NH1 . ARG A 1 777 ? 43.469 76.664 -24.345 1.00 27.82 ? 777 ARG A NH1 1 ATOM 6196 N NH2 . ARG A 1 777 ? 44.112 74.546 -25.026 1.00 27.59 ? 777 ARG A NH2 1 ATOM 6197 N N . ASN A 1 778 ? 35.778 76.050 -21.311 1.00 11.58 ? 778 ASN A N 1 ATOM 6198 C CA . ASN A 1 778 ? 34.843 76.998 -20.769 1.00 11.35 ? 778 ASN A CA 1 ATOM 6199 C C . ASN A 1 778 ? 35.506 77.826 -19.692 1.00 13.62 ? 778 ASN A C 1 ATOM 6200 O O . ASN A 1 778 ? 35.974 77.268 -18.670 1.00 13.40 ? 778 ASN A O 1 ATOM 6201 C CB . ASN A 1 778 ? 33.624 76.329 -20.116 1.00 13.44 ? 778 ASN A CB 1 ATOM 6202 C CG . ASN A 1 778 ? 32.710 75.663 -21.093 1.00 14.34 ? 778 ASN A CG 1 ATOM 6203 O OD1 . ASN A 1 778 ? 32.691 76.007 -22.278 1.00 15.30 ? 778 ASN A OD1 1 ATOM 6204 N ND2 . ASN A 1 778 ? 31.909 74.698 -20.598 1.00 13.31 ? 778 ASN A ND2 1 ATOM 6205 N N . LEU A 1 779 ? 35.583 79.139 -19.903 1.00 13.62 ? 779 LEU A N 1 ATOM 6206 C CA . LEU A 1 779 ? 36.086 80.011 -18.844 1.00 12.99 ? 779 LEU A CA 1 ATOM 6207 C C . LEU A 1 779 ? 34.836 80.425 -18.088 1.00 13.39 ? 779 LEU A C 1 ATOM 6208 O O . LEU A 1 779 ? 34.030 81.230 -18.579 1.00 14.08 ? 779 LEU A O 1 ATOM 6209 C CB . LEU A 1 779 ? 36.824 81.214 -19.451 1.00 16.08 ? 779 LEU A CB 1 ATOM 6210 C CG . LEU A 1 779 ? 37.369 82.193 -18.400 1.00 18.92 ? 779 LEU A CG 1 ATOM 6211 C CD1 . LEU A 1 779 ? 38.381 81.538 -17.515 1.00 22.38 ? 779 LEU A CD1 1 ATOM 6212 C CD2 . LEU A 1 779 ? 38.010 83.412 -19.131 1.00 23.55 ? 779 LEU A CD2 1 ATOM 6213 N N . VAL A 1 780 ? 34.626 79.801 -16.930 1.00 12.46 ? 780 VAL A N 1 ATOM 6214 C CA . VAL A 1 780 ? 33.388 79.983 -16.173 1.00 14.62 ? 780 VAL A CA 1 ATOM 6215 C C . VAL A 1 780 ? 33.523 80.988 -15.021 1.00 14.67 ? 780 VAL A C 1 ATOM 6216 O O . VAL A 1 780 ? 34.319 80.790 -14.082 1.00 14.42 ? 780 VAL A O 1 ATOM 6217 C CB . VAL A 1 780 ? 32.905 78.602 -15.628 1.00 13.77 ? 780 VAL A CB 1 ATOM 6218 C CG1 . VAL A 1 780 ? 31.579 78.790 -14.886 1.00 14.02 ? 780 VAL A CG1 1 ATOM 6219 C CG2 . VAL A 1 780 ? 32.797 77.588 -16.749 1.00 12.84 ? 780 VAL A CG2 1 ATOM 6220 N N . ASP A 1 781 ? 32.783 82.092 -15.125 1.00 14.34 ? 781 ASP A N 1 ATOM 6221 C CA . ASP A 1 781 ? 32.776 83.111 -14.079 1.00 14.90 ? 781 ASP A CA 1 ATOM 6222 C C . ASP A 1 781 ? 31.343 83.428 -13.705 1.00 15.92 ? 781 ASP A C 1 ATOM 6223 O O . ASP A 1 781 ? 30.661 84.278 -14.356 1.00 15.62 ? 781 ASP A O 1 ATOM 6224 C CB . ASP A 1 781 ? 33.471 84.373 -14.557 1.00 17.67 ? 781 ASP A CB 1 ATOM 6225 C CG . ASP A 1 781 ? 33.542 85.423 -13.471 1.00 18.06 ? 781 ASP A CG 1 ATOM 6226 O OD1 . ASP A 1 781 ? 33.044 85.195 -12.350 1.00 18.43 ? 781 ASP A OD1 1 ATOM 6227 O OD2 . ASP A 1 781 ? 34.119 86.498 -13.739 1.00 24.27 ? 781 ASP A OD2 1 ATOM 6228 N N . ILE A 1 782 ? 30.839 82.719 -12.699 1.00 14.85 ? 782 ILE A N 1 ATOM 6229 C CA . ILE A 1 782 ? 29.438 82.860 -12.272 1.00 17.97 ? 782 ILE A CA 1 ATOM 6230 C C . ILE A 1 782 ? 29.158 84.204 -11.630 1.00 20.80 ? 782 ILE A C 1 ATOM 6231 O O . ILE A 1 782 ? 27.995 84.550 -11.329 1.00 22.79 ? 782 ILE A O 1 ATOM 6232 C CB . ILE A 1 782 ? 29.068 81.654 -11.370 1.00 18.29 ? 782 ILE A CB 1 ATOM 6233 C CG1 . ILE A 1 782 ? 27.569 81.531 -11.182 1.00 21.97 ? 782 ILE A CG1 1 ATOM 6234 C CG2 . ILE A 1 782 ? 29.742 81.816 -10.021 1.00 18.91 ? 782 ILE A CG2 1 ATOM 6235 C CD1 . ILE A 1 782 ? 27.206 80.145 -10.692 1.00 23.19 ? 782 ILE A CD1 1 ATOM 6236 N N . GLY A 1 783 ? 30.234 84.961 -11.414 1.00 19.61 ? 783 GLY A N 1 ATOM 6237 C CA . GLY A 1 783 ? 30.098 86.327 -10.912 1.00 21.79 ? 783 GLY A CA 1 ATOM 6238 C C . GLY A 1 783 ? 29.231 86.433 -9.678 1.00 22.19 ? 783 GLY A C 1 ATOM 6239 O O . GLY A 1 783 ? 29.443 85.681 -8.732 1.00 26.23 ? 783 GLY A O 1 ATOM 6240 N N . SER A 1 784 ? 28.237 87.325 -9.678 1.00 24.62 ? 784 SER A N 1 ATOM 6241 C CA . SER A 1 784 ? 27.407 87.442 -8.487 1.00 26.31 ? 784 SER A CA 1 ATOM 6242 C C . SER A 1 784 ? 26.012 86.842 -8.636 1.00 27.53 ? 784 SER A C 1 ATOM 6243 O O . SER A 1 784 ? 25.061 87.243 -7.928 1.00 28.02 ? 784 SER A O 1 ATOM 6244 C CB . SER A 1 784 ? 27.302 88.902 -8.045 1.00 29.05 ? 784 SER A CB 1 ATOM 6245 O OG . SER A 1 784 ? 26.670 89.707 -9.035 1.00 34.64 ? 784 SER A OG 1 ATOM 6246 N N . LEU A 1 785 ? 25.878 85.871 -9.538 1.00 26.77 ? 785 LEU A N 1 ATOM 6247 C CA . LEU A 1 785 ? 24.579 85.226 -9.730 1.00 26.56 ? 785 LEU A CA 1 ATOM 6248 C C . LEU A 1 785 ? 24.251 84.316 -8.560 1.00 27.89 ? 785 LEU A C 1 ATOM 6249 O O . LEU A 1 785 ? 24.563 83.119 -8.575 1.00 28.56 ? 785 LEU A O 1 ATOM 6250 C CB . LEU A 1 785 ? 24.573 84.405 -11.022 1.00 27.24 ? 785 LEU A CB 1 ATOM 6251 C CG . LEU A 1 785 ? 24.877 85.179 -12.306 1.00 28.32 ? 785 LEU A CG 1 ATOM 6252 C CD1 . LEU A 1 785 ? 24.961 84.225 -13.474 1.00 30.30 ? 785 LEU A CD1 1 ATOM 6253 C CD2 . LEU A 1 785 ? 23.807 86.244 -12.508 1.00 28.84 ? 785 LEU A CD2 1 ATOM 6254 N N . ASP A 1 786 ? 23.584 84.843 -7.550 1.00 27.64 ? 786 ASP A N 1 ATOM 6255 C CA . ASP A 1 786 ? 23.264 84.017 -6.402 1.00 25.87 ? 786 ASP A CA 1 ATOM 6256 C C . ASP A 1 786 ? 22.215 82.938 -6.711 1.00 21.70 ? 786 ASP A C 1 ATOM 6257 O O . ASP A 1 786 ? 21.371 83.075 -7.607 1.00 22.05 ? 786 ASP A O 1 ATOM 6258 C CB . ASP A 1 786 ? 22.780 84.871 -5.225 1.00 30.42 ? 786 ASP A CB 1 ATOM 6259 C CG . ASP A 1 786 ? 23.916 85.573 -4.481 1.00 33.71 ? 786 ASP A CG 1 ATOM 6260 O OD1 . ASP A 1 786 ? 25.076 85.641 -4.962 1.00 30.85 ? 786 ASP A OD1 1 ATOM 6261 O OD2 . ASP A 1 786 ? 23.635 86.090 -3.378 1.00 38.80 ? 786 ASP A OD2 1 ATOM 6262 N N . ASN A 1 787 ? 22.345 81.840 -5.983 1.00 20.26 ? 787 ASN A N 1 ATOM 6263 C CA . ASN A 1 787 ? 21.438 80.710 -6.093 1.00 18.43 ? 787 ASN A CA 1 ATOM 6264 C C . ASN A 1 787 ? 21.251 80.249 -7.511 1.00 18.55 ? 787 ASN A C 1 ATOM 6265 O O . ASN A 1 787 ? 20.138 80.054 -7.985 1.00 18.50 ? 787 ASN A O 1 ATOM 6266 C CB . ASN A 1 787 ? 20.114 81.065 -5.402 1.00 20.53 ? 787 ASN A CB 1 ATOM 6267 C CG . ASN A 1 787 ? 20.334 81.351 -3.970 1.00 23.45 ? 787 ASN A CG 1 ATOM 6268 O OD1 . ASN A 1 787 ? 21.057 80.606 -3.301 1.00 23.44 ? 787 ASN A OD1 1 ATOM 6269 N ND2 . ASN A 1 787 ? 19.744 82.446 -3.463 1.00 30.61 ? 787 ASN A ND2 1 ATOM 6270 N N . THR A 1 788 ? 22.383 80.020 -8.172 1.00 16.52 ? 788 THR A N 1 ATOM 6271 C CA . THR A 1 788 ? 22.386 79.615 -9.562 1.00 16.69 ? 788 THR A CA 1 ATOM 6272 C C . THR A 1 788 ? 23.417 78.520 -9.786 1.00 14.94 ? 788 THR A C 1 ATOM 6273 O O . THR A 1 788 ? 24.502 78.582 -9.212 1.00 15.30 ? 788 THR A O 1 ATOM 6274 C CB . THR A 1 788 ? 22.797 80.805 -10.465 1.00 18.06 ? 788 THR A CB 1 ATOM 6275 O OG1 . THR A 1 788 ? 21.819 81.861 -10.306 1.00 20.66 ? 788 THR A OG1 1 ATOM 6276 C CG2 . THR A 1 788 ? 22.841 80.396 -11.936 1.00 21.02 ? 788 THR A CG2 1 ATOM 6277 N N . GLU A 1 789 ? 23.042 77.506 -10.554 1.00 14.93 ? 789 GLU A N 1 ATOM 6278 C CA . GLU A 1 789 ? 23.992 76.483 -10.955 1.00 13.92 ? 789 GLU A CA 1 ATOM 6279 C C . GLU A 1 789 ? 23.964 76.501 -12.477 1.00 15.37 ? 789 GLU A C 1 ATOM 6280 O O . GLU A 1 789 ? 22.889 76.390 -13.105 1.00 16.86 ? 789 GLU A O 1 ATOM 6281 C CB . GLU A 1 789 ? 23.636 75.083 -10.380 1.00 14.95 ? 789 GLU A CB 1 ATOM 6282 C CG . GLU A 1 789 ? 23.255 75.130 -8.915 1.00 15.30 ? 789 GLU A CG 1 ATOM 6283 C CD . GLU A 1 789 ? 23.456 73.801 -8.175 1.00 14.19 ? 789 GLU A CD 1 ATOM 6284 O OE1 . GLU A 1 789 ? 24.277 72.963 -8.675 1.00 14.89 ? 789 GLU A OE1 1 ATOM 6285 O OE2 . GLU A 1 789 ? 22.792 73.638 -7.124 1.00 14.71 ? 789 GLU A OE2 1 ATOM 6286 N N . ILE A 1 790 ? 25.121 76.673 -13.093 1.00 12.93 ? 790 ILE A N 1 ATOM 6287 C CA . ILE A 1 790 ? 25.231 76.699 -14.551 1.00 15.64 ? 790 ILE A CA 1 ATOM 6288 C C . ILE A 1 790 ? 25.591 75.328 -15.080 1.00 14.67 ? 790 ILE A C 1 ATOM 6289 O O . ILE A 1 790 ? 26.598 74.732 -14.643 1.00 14.95 ? 790 ILE A O 1 ATOM 6290 C CB . ILE A 1 790 ? 26.342 77.669 -15.008 1.00 16.46 ? 790 ILE A CB 1 ATOM 6291 C CG1 . ILE A 1 790 ? 25.982 79.111 -14.569 1.00 21.82 ? 790 ILE A CG1 1 ATOM 6292 C CG2 . ILE A 1 790 ? 26.474 77.605 -16.548 1.00 18.31 ? 790 ILE A CG2 1 ATOM 6293 C CD1 . ILE A 1 790 ? 27.196 80.072 -14.595 1.00 25.14 ? 790 ILE A CD1 1 ATOM 6294 N N . VAL A 1 791 ? 24.789 74.822 -16.005 1.00 14.16 ? 791 VAL A N 1 ATOM 6295 C CA . VAL A 1 791 ? 25.021 73.519 -16.580 1.00 13.71 ? 791 VAL A CA 1 ATOM 6296 C C . VAL A 1 791 ? 25.274 73.611 -18.068 1.00 13.11 ? 791 VAL A C 1 ATOM 6297 O O . VAL A 1 791 ? 24.651 74.475 -18.787 1.00 14.41 ? 791 VAL A O 1 ATOM 6298 C CB . VAL A 1 791 ? 23.788 72.541 -16.300 1.00 13.86 ? 791 VAL A CB 1 ATOM 6299 C CG1 . VAL A 1 791 ? 22.525 73.001 -17.097 1.00 17.76 ? 791 VAL A CG1 1 ATOM 6300 C CG2 . VAL A 1 791 ? 24.146 71.073 -16.690 1.00 14.70 ? 791 VAL A CG2 1 ATOM 6301 N N . MET A 1 792 ? 26.179 72.783 -18.565 1.00 13.01 ? 792 MET A N 1 ATOM 6302 C CA . MET A 1 792 ? 26.421 72.676 -20.000 1.00 12.55 ? 792 MET A CA 1 ATOM 6303 C C . MET A 1 792 ? 25.736 71.369 -20.467 1.00 13.58 ? 792 MET A C 1 ATOM 6304 O O . MET A 1 792 ? 26.074 70.283 -19.971 1.00 14.21 ? 792 MET A O 1 ATOM 6305 C CB . MET A 1 792 ? 27.916 72.621 -20.327 1.00 14.63 ? 792 MET A CB 1 ATOM 6306 C CG . MET A 1 792 ? 28.197 72.412 -21.812 1.00 16.16 ? 792 MET A CG 1 ATOM 6307 S SD . MET A 1 792 ? 29.955 72.538 -22.194 1.00 14.87 ? 792 MET A SD 1 ATOM 6308 C CE . MET A 1 792 ? 30.580 71.037 -21.337 1.00 16.19 ? 792 MET A CE 1 ATOM 6309 N N . ARG A 1 793 ? 24.815 71.451 -21.420 1.00 14.20 ? 793 ARG A N 1 ATOM 6310 C CA . ARG A 1 793 ? 24.100 70.284 -21.913 1.00 15.44 ? 793 ARG A CA 1 ATOM 6311 C C . ARG A 1 793 ? 24.404 70.061 -23.383 1.00 14.32 ? 793 ARG A C 1 ATOM 6312 O O . ARG A 1 793 ? 24.618 71.023 -24.141 1.00 14.26 ? 793 ARG A O 1 ATOM 6313 C CB . ARG A 1 793 ? 22.591 70.499 -21.719 1.00 15.06 ? 793 ARG A CB 1 ATOM 6314 C CG . ARG A 1 793 ? 21.722 69.294 -22.187 1.00 14.30 ? 793 ARG A CG 1 ATOM 6315 C CD . ARG A 1 793 ? 20.247 69.526 -21.881 1.00 13.90 ? 793 ARG A CD 1 ATOM 6316 N NE . ARG A 1 793 ? 20.010 69.572 -20.450 1.00 16.94 ? 793 ARG A NE 1 ATOM 6317 C CZ . ARG A 1 793 ? 18.956 70.154 -19.886 1.00 17.15 ? 793 ARG A CZ 1 ATOM 6318 N NH1 . ARG A 1 793 ? 18.030 70.743 -20.675 1.00 16.17 ? 793 ARG A NH1 1 ATOM 6319 N NH2 . ARG A 1 793 ? 18.822 70.202 -18.577 1.00 18.32 ? 793 ARG A NH2 1 ATOM 6320 N N . LEU A 1 794 ? 24.427 68.803 -23.784 1.00 13.90 ? 794 LEU A N 1 ATOM 6321 C CA . LEU A 1 794 ? 24.578 68.357 -25.159 1.00 13.60 ? 794 LEU A CA 1 ATOM 6322 C C . LEU A 1 794 ? 23.253 67.672 -25.521 1.00 16.13 ? 794 LEU A C 1 ATOM 6323 O O . LEU A 1 794 ? 22.748 66.799 -24.785 1.00 15.59 ? 794 LEU A O 1 ATOM 6324 C CB . LEU A 1 794 ? 25.731 67.364 -25.281 1.00 16.08 ? 794 LEU A CB 1 ATOM 6325 C CG . LEU A 1 794 ? 27.092 68.030 -25.392 1.00 14.98 ? 794 LEU A CG 1 ATOM 6326 C CD1 . LEU A 1 794 ? 28.215 67.042 -24.995 1.00 17.78 ? 794 LEU A CD1 1 ATOM 6327 C CD2 . LEU A 1 794 ? 27.277 68.481 -26.835 1.00 19.71 ? 794 LEU A CD2 1 ATOM 6328 N N . GLU A 1 795 ? 22.665 68.101 -26.646 1.00 16.09 ? 795 GLU A N 1 ATOM 6329 C CA . GLU A 1 795 ? 21.409 67.514 -27.133 1.00 17.34 ? 795 GLU A CA 1 ATOM 6330 C C . GLU A 1 795 ? 21.700 66.798 -28.425 1.00 18.43 ? 795 GLU A C 1 ATOM 6331 O O . GLU A 1 795 ? 22.260 67.361 -29.354 1.00 18.59 ? 795 GLU A O 1 ATOM 6332 C CB . GLU A 1 795 ? 20.329 68.586 -27.349 1.00 17.51 ? 795 GLU A CB 1 ATOM 6333 C CG . GLU A 1 795 ? 19.944 69.297 -26.084 1.00 21.01 ? 795 GLU A CG 1 ATOM 6334 C CD . GLU A 1 795 ? 19.034 70.525 -26.289 1.00 25.45 ? 795 GLU A CD 1 ATOM 6335 O OE1 . GLU A 1 795 ? 19.038 71.099 -27.407 1.00 30.00 ? 795 GLU A OE1 1 ATOM 6336 O OE2 . GLU A 1 795 ? 18.335 70.937 -25.334 1.00 26.06 ? 795 GLU A OE2 1 ATOM 6337 N N . THR A 1 796 ? 21.349 65.518 -28.491 1.00 16.47 ? 796 THR A N 1 ATOM 6338 C CA . THR A 1 796 ? 21.568 64.739 -29.681 1.00 17.77 ? 796 THR A CA 1 ATOM 6339 C C . THR A 1 796 ? 20.326 63.911 -29.996 1.00 16.25 ? 796 THR A C 1 ATOM 6340 O O . THR A 1 796 ? 19.342 63.957 -29.236 1.00 20.45 ? 796 THR A O 1 ATOM 6341 C CB . THR A 1 796 ? 22.744 63.728 -29.552 1.00 17.02 ? 796 THR A CB 1 ATOM 6342 O OG1 . THR A 1 796 ? 22.334 62.546 -28.829 1.00 16.63 ? 796 THR A OG1 1 ATOM 6343 C CG2 . THR A 1 796 ? 23.911 64.379 -28.765 1.00 17.40 ? 796 THR A CG2 1 ATOM 6344 N N . HIS A 1 797 ? 20.423 63.158 -31.075 1.00 19.53 ? 797 HIS A N 1 ATOM 6345 C CA . HIS A 1 797 ? 19.349 62.270 -31.500 1.00 20.74 ? 797 HIS A CA 1 ATOM 6346 C C A HIS A 1 797 ? 19.514 60.873 -30.997 0.50 20.18 ? 797 HIS A C 1 ATOM 6347 C C B HIS A 1 797 ? 19.737 60.795 -31.319 0.50 22.01 ? 797 HIS A C 1 ATOM 6348 O O A HIS A 1 797 ? 18.575 60.079 -31.116 0.50 18.37 ? 797 HIS A O 1 ATOM 6349 O O B HIS A 1 797 ? 19.212 59.875 -31.940 0.50 20.21 ? 797 HIS A O 1 ATOM 6350 C CB A HIS A 1 797 ? 19.327 62.181 -33.017 0.50 21.46 ? 797 HIS A CB 1 ATOM 6351 C CB B HIS A 1 797 ? 19.058 62.490 -33.027 0.50 25.37 ? 797 HIS A CB 1 ATOM 6352 C CG A HIS A 1 797 ? 18.634 63.328 -33.648 0.50 20.60 ? 797 HIS A CG 1 ATOM 6353 C CG B HIS A 1 797 ? 18.332 63.768 -33.283 0.50 27.15 ? 797 HIS A CG 1 ATOM 6354 N ND1 A HIS A 1 797 ? 18.774 63.657 -34.978 0.50 19.92 ? 797 HIS A ND1 1 ATOM 6355 N ND1 B HIS A 1 797 ? 18.172 64.284 -34.550 0.50 27.35 ? 797 HIS A ND1 1 ATOM 6356 C CD2 A HIS A 1 797 ? 17.809 64.252 -33.107 0.50 18.32 ? 797 HIS A CD2 1 ATOM 6357 C CD2 B HIS A 1 797 ? 17.752 64.652 -32.437 0.50 26.26 ? 797 HIS A CD2 1 ATOM 6358 C CE1 A HIS A 1 797 ? 18.063 64.742 -35.228 0.50 19.38 ? 797 HIS A CE1 1 ATOM 6359 C CE1 B HIS A 1 797 ? 17.527 65.431 -34.474 0.50 28.39 ? 797 HIS A CE1 1 ATOM 6360 N NE2 A HIS A 1 797 ? 17.471 65.122 -34.108 0.50 14.52 ? 797 HIS A NE2 1 ATOM 6361 N NE2 B HIS A 1 797 ? 17.258 65.680 -33.208 0.50 25.69 ? 797 HIS A NE2 1 ATOM 6362 N N . ILE A 1 798 ? 20.700 60.585 -30.436 1.00 19.92 ? 798 ILE A N 1 ATOM 6363 C CA . ILE A 1 798 ? 21.082 59.247 -30.024 1.00 18.16 ? 798 ILE A CA 1 ATOM 6364 C C . ILE A 1 798 ? 19.974 58.670 -29.160 1.00 16.53 ? 798 ILE A C 1 ATOM 6365 O O . ILE A 1 798 ? 19.442 59.318 -28.238 1.00 17.52 ? 798 ILE A O 1 ATOM 6366 C CB . ILE A 1 798 ? 22.430 59.274 -29.274 1.00 16.50 ? 798 ILE A CB 1 ATOM 6367 C CG1 . ILE A 1 798 ? 23.547 59.708 -30.222 1.00 16.97 ? 798 ILE A CG1 1 ATOM 6368 C CG2 . ILE A 1 798 ? 22.709 57.877 -28.693 1.00 19.14 ? 798 ILE A CG2 1 ATOM 6369 C CD1 . ILE A 1 798 ? 24.913 60.062 -29.499 1.00 20.31 ? 798 ILE A CD1 1 ATOM 6370 N N . ASP A 1 799 ? 19.564 57.440 -29.538 1.00 18.58 ? 799 ASP A N 1 ATOM 6371 C CA . ASP A 1 799 ? 18.475 56.754 -28.880 1.00 16.62 ? 799 ASP A CA 1 ATOM 6372 C C . ASP A 1 799 ? 18.988 55.993 -27.667 1.00 19.63 ? 799 ASP A C 1 ATOM 6373 O O . ASP A 1 799 ? 18.967 54.792 -27.616 1.00 18.10 ? 799 ASP A O 1 ATOM 6374 C CB . ASP A 1 799 ? 17.809 55.764 -29.878 1.00 20.53 ? 799 ASP A CB 1 ATOM 6375 C CG . ASP A 1 799 ? 16.470 55.251 -29.386 1.00 22.93 ? 799 ASP A CG 1 ATOM 6376 O OD1 . ASP A 1 799 ? 15.879 55.799 -28.461 1.00 29.28 ? 799 ASP A OD1 1 ATOM 6377 O OD2 . ASP A 1 799 ? 16.012 54.248 -29.948 1.00 30.10 ? 799 ASP A OD2 1 ATOM 6378 N N . SER A 1 800 ? 19.421 56.748 -26.668 1.00 17.74 ? 800 SER A N 1 ATOM 6379 C CA . SER A 1 800 ? 19.981 56.154 -25.463 1.00 17.90 ? 800 SER A CA 1 ATOM 6380 C C . SER A 1 800 ? 18.920 55.767 -24.446 1.00 16.80 ? 800 SER A C 1 ATOM 6381 O O . SER A 1 800 ? 19.188 54.991 -23.538 1.00 16.15 ? 800 SER A O 1 ATOM 6382 C CB . SER A 1 800 ? 20.988 57.157 -24.858 1.00 16.47 ? 800 SER A CB 1 ATOM 6383 O OG . SER A 1 800 ? 20.346 58.367 -24.524 1.00 16.06 ? 800 SER A OG 1 ATOM 6384 N N . GLY A 1 801 ? 17.712 56.297 -24.557 1.00 14.87 ? 801 GLY A N 1 ATOM 6385 C CA . GLY A 1 801 ? 16.659 55.939 -23.620 1.00 16.70 ? 801 GLY A CA 1 ATOM 6386 C C . GLY A 1 801 ? 16.907 56.495 -22.258 1.00 16.30 ? 801 GLY A C 1 ATOM 6387 O O . GLY A 1 801 ? 16.922 57.698 -22.055 1.00 18.65 ? 801 GLY A O 1 ATOM 6388 N N . ASP A 1 802 ? 17.056 55.589 -21.316 1.00 15.22 ? 802 ASP A N 1 ATOM 6389 C CA . ASP A 1 802 ? 17.328 55.965 -19.941 1.00 14.88 ? 802 ASP A CA 1 ATOM 6390 C C . ASP A 1 802 ? 18.702 55.496 -19.496 1.00 15.93 ? 802 ASP A C 1 ATOM 6391 O O . ASP A 1 802 ? 18.971 55.531 -18.297 1.00 16.39 ? 802 ASP A O 1 ATOM 6392 C CB . ASP A 1 802 ? 16.244 55.392 -18.989 1.00 17.39 ? 802 ASP A CB 1 ATOM 6393 C CG . ASP A 1 802 ? 16.090 53.874 -19.101 1.00 17.41 ? 802 ASP A CG 1 ATOM 6394 O OD1 . ASP A 1 802 ? 16.873 53.225 -19.833 1.00 22.29 ? 802 ASP A OD1 1 ATOM 6395 O OD2 . ASP A 1 802 ? 15.171 53.330 -18.425 1.00 21.71 ? 802 ASP A OD2 1 ATOM 6396 N N . ILE A 1 803 ? 19.552 55.111 -20.432 1.00 14.07 ? 803 ILE A N 1 ATOM 6397 C CA . ILE A 1 803 ? 20.886 54.618 -20.081 1.00 14.99 ? 803 ILE A CA 1 ATOM 6398 C C . ILE A 1 803 ? 21.990 55.609 -20.418 1.00 15.31 ? 803 ILE A C 1 ATOM 6399 O O . ILE A 1 803 ? 21.946 56.265 -21.452 1.00 14.94 ? 803 ILE A O 1 ATOM 6400 C CB . ILE A 1 803 ? 21.183 53.310 -20.860 1.00 14.60 ? 803 ILE A CB 1 ATOM 6401 C CG1 . ILE A 1 803 ? 20.154 52.218 -20.468 1.00 15.32 ? 803 ILE A CG1 1 ATOM 6402 C CG2 . ILE A 1 803 ? 22.638 52.824 -20.626 1.00 14.76 ? 803 ILE A CG2 1 ATOM 6403 C CD1 . ILE A 1 803 ? 20.139 51.883 -18.973 1.00 18.61 ? 803 ILE A CD1 1 ATOM 6404 N N . PHE A 1 804 ? 22.981 55.722 -19.520 1.00 14.36 ? 804 PHE A N 1 ATOM 6405 C CA . PHE A 1 804 ? 24.150 56.531 -19.774 1.00 13.39 ? 804 PHE A CA 1 ATOM 6406 C C . PHE A 1 804 ? 25.277 55.919 -18.943 1.00 12.43 ? 804 PHE A C 1 ATOM 6407 O O . PHE A 1 804 ? 25.031 55.054 -18.118 1.00 14.69 ? 804 PHE A O 1 ATOM 6408 C CB . PHE A 1 804 ? 23.933 58.029 -19.455 1.00 13.08 ? 804 PHE A CB 1 ATOM 6409 C CG . PHE A 1 804 ? 23.514 58.343 -18.058 1.00 12.58 ? 804 PHE A CG 1 ATOM 6410 C CD1 . PHE A 1 804 ? 22.222 58.114 -17.604 1.00 12.37 ? 804 PHE A CD1 1 ATOM 6411 C CD2 . PHE A 1 804 ? 24.449 58.976 -17.183 1.00 13.19 ? 804 PHE A CD2 1 ATOM 6412 C CE1 . PHE A 1 804 ? 21.837 58.492 -16.333 1.00 12.86 ? 804 PHE A CE1 1 ATOM 6413 C CE2 . PHE A 1 804 ? 24.090 59.363 -15.925 1.00 12.99 ? 804 PHE A CE2 1 ATOM 6414 C CZ . PHE A 1 804 ? 22.791 59.132 -15.466 1.00 13.60 ? 804 PHE A CZ 1 ATOM 6415 N N . TYR A 1 805 ? 26.492 56.360 -19.185 1.00 11.60 ? 805 TYR A N 1 ATOM 6416 C CA . TYR A 1 805 ? 27.651 55.808 -18.491 1.00 11.14 ? 805 TYR A CA 1 ATOM 6417 C C . TYR A 1 805 ? 28.469 56.915 -17.930 1.00 12.98 ? 805 TYR A C 1 ATOM 6418 O O . TYR A 1 805 ? 28.617 57.954 -18.576 1.00 13.66 ? 805 TYR A O 1 ATOM 6419 C CB . TYR A 1 805 ? 28.510 55.011 -19.483 1.00 12.27 ? 805 TYR A CB 1 ATOM 6420 C CG . TYR A 1 805 ? 27.808 53.781 -20.041 1.00 12.80 ? 805 TYR A CG 1 ATOM 6421 C CD1 . TYR A 1 805 ? 26.846 53.898 -21.035 1.00 13.74 ? 805 TYR A CD1 1 ATOM 6422 C CD2 . TYR A 1 805 ? 28.104 52.521 -19.537 1.00 12.16 ? 805 TYR A CD2 1 ATOM 6423 C CE1 . TYR A 1 805 ? 26.192 52.757 -21.511 1.00 13.11 ? 805 TYR A CE1 1 ATOM 6424 C CE2 . TYR A 1 805 ? 27.462 51.366 -20.002 1.00 12.54 ? 805 TYR A CE2 1 ATOM 6425 C CZ . TYR A 1 805 ? 26.509 51.525 -20.993 1.00 13.27 ? 805 TYR A CZ 1 ATOM 6426 O OH . TYR A 1 805 ? 25.920 50.398 -21.548 1.00 15.98 ? 805 TYR A OH 1 ATOM 6427 N N . THR A 1 806 ? 28.991 56.697 -16.722 1.00 12.75 ? 806 THR A N 1 ATOM 6428 C CA . THR A 1 806 ? 29.855 57.693 -16.084 1.00 11.38 ? 806 THR A CA 1 ATOM 6429 C C . THR A 1 806 ? 31.023 56.909 -15.500 1.00 12.67 ? 806 THR A C 1 ATOM 6430 O O . THR A 1 806 ? 30.906 55.686 -15.258 1.00 13.18 ? 806 THR A O 1 ATOM 6431 C CB . THR A 1 806 ? 29.143 58.476 -14.977 1.00 11.27 ? 806 THR A CB 1 ATOM 6432 O OG1 . THR A 1 806 ? 28.769 57.600 -13.919 1.00 13.53 ? 806 THR A OG1 1 ATOM 6433 C CG2 . THR A 1 806 ? 27.876 59.143 -15.487 1.00 11.16 ? 806 THR A CG2 1 ATOM 6434 N N . ASP A 1 807 ? 32.152 57.569 -15.302 1.00 10.81 ? 807 ASP A N 1 ATOM 6435 C CA . ASP A 1 807 ? 33.273 56.839 -14.730 1.00 12.96 ? 807 ASP A CA 1 ATOM 6436 C C . ASP A 1 807 ? 33.369 56.944 -13.213 1.00 10.55 ? 807 ASP A C 1 ATOM 6437 O O . ASP A 1 807 ? 32.714 57.766 -12.565 1.00 11.39 ? 807 ASP A O 1 ATOM 6438 C CB . ASP A 1 807 ? 34.586 57.310 -15.360 1.00 13.05 ? 807 ASP A CB 1 ATOM 6439 C CG . ASP A 1 807 ? 35.038 58.641 -14.854 1.00 12.48 ? 807 ASP A CG 1 ATOM 6440 O OD1 . ASP A 1 807 ? 34.276 59.632 -14.944 1.00 14.41 ? 807 ASP A OD1 1 ATOM 6441 O OD2 . ASP A 1 807 ? 36.201 58.700 -14.342 1.00 15.25 ? 807 ASP A OD2 1 ATOM 6442 N N . LEU A 1 808 ? 34.136 56.023 -12.672 1.00 11.08 ? 808 LEU A N 1 ATOM 6443 C CA . LEU A 1 808 ? 34.414 56.015 -11.230 1.00 10.88 ? 808 LEU A CA 1 ATOM 6444 C C . LEU A 1 808 ? 35.902 56.225 -11.063 1.00 10.67 ? 808 LEU A C 1 ATOM 6445 O O . LEU A 1 808 ? 36.714 55.401 -11.508 1.00 10.54 ? 808 LEU A O 1 ATOM 6446 C CB . LEU A 1 808 ? 33.979 54.689 -10.579 1.00 12.61 ? 808 LEU A CB 1 ATOM 6447 C CG . LEU A 1 808 ? 32.452 54.549 -10.534 1.00 12.54 ? 808 LEU A CG 1 ATOM 6448 C CD1 . LEU A 1 808 ? 32.074 53.080 -10.319 1.00 13.57 ? 808 LEU A CD1 1 ATOM 6449 C CD2 . LEU A 1 808 ? 31.881 55.345 -9.353 1.00 13.87 ? 808 LEU A CD2 1 ATOM 6450 N N . ASN A 1 809 ? 36.248 57.389 -10.509 1.00 10.79 ? 809 ASN A N 1 ATOM 6451 C CA . ASN A 1 809 ? 37.631 57.722 -10.183 1.00 11.65 ? 809 ASN A CA 1 ATOM 6452 C C . ASN A 1 809 ? 38.600 57.600 -11.334 1.00 10.60 ? 809 ASN A C 1 ATOM 6453 O O . ASN A 1 809 ? 39.769 57.329 -11.134 1.00 11.33 ? 809 ASN A O 1 ATOM 6454 C CB . ASN A 1 809 ? 38.125 56.832 -9.020 1.00 9.96 ? 809 ASN A CB 1 ATOM 6455 C CG . ASN A 1 809 ? 37.078 56.726 -7.923 1.00 10.68 ? 809 ASN A CG 1 ATOM 6456 O OD1 . ASN A 1 809 ? 36.238 55.820 -7.932 1.00 10.31 ? 809 ASN A OD1 1 ATOM 6457 N ND2 . ASN A 1 809 ? 37.103 57.661 -6.992 1.00 11.43 ? 809 ASN A ND2 1 ATOM 6458 N N . GLY A 1 810 ? 38.105 57.785 -12.570 1.00 9.99 ? 810 GLY A N 1 ATOM 6459 C CA . GLY A 1 810 ? 39.035 57.701 -13.712 1.00 12.35 ? 810 GLY A CA 1 ATOM 6460 C C . GLY A 1 810 ? 39.558 56.299 -13.976 1.00 12.71 ? 810 GLY A C 1 ATOM 6461 O O . GLY A 1 810 ? 40.496 56.134 -14.766 1.00 15.13 ? 810 GLY A O 1 ATOM 6462 N N . LEU A 1 811 ? 38.931 55.305 -13.352 1.00 11.77 ? 811 LEU A N 1 ATOM 6463 C CA . LEU A 1 811 ? 39.351 53.922 -13.420 1.00 12.19 ? 811 LEU A CA 1 ATOM 6464 C C . LEU A 1 811 ? 38.466 53.019 -14.272 1.00 13.69 ? 811 LEU A C 1 ATOM 6465 O O . LEU A 1 811 ? 38.972 52.133 -14.970 1.00 15.26 ? 811 LEU A O 1 ATOM 6466 C CB . LEU A 1 811 ? 39.391 53.372 -11.978 1.00 13.26 ? 811 LEU A CB 1 ATOM 6467 C CG . LEU A 1 811 ? 39.811 51.895 -11.896 1.00 14.30 ? 811 LEU A CG 1 ATOM 6468 C CD1 . LEU A 1 811 ? 41.221 51.704 -12.447 1.00 15.84 ? 811 LEU A CD1 1 ATOM 6469 C CD2 . LEU A 1 811 ? 39.726 51.447 -10.428 1.00 14.13 ? 811 LEU A CD2 1 ATOM 6470 N N . GLN A 1 812 ? 37.163 53.254 -14.241 1.00 11.36 ? 812 GLN A N 1 ATOM 6471 C CA . GLN A 1 812 ? 36.228 52.335 -14.922 1.00 10.73 ? 812 GLN A CA 1 ATOM 6472 C C . GLN A 1 812 ? 34.948 53.078 -15.245 1.00 11.27 ? 812 GLN A C 1 ATOM 6473 O O . GLN A 1 812 ? 34.645 54.089 -14.599 1.00 12.48 ? 812 GLN A O 1 ATOM 6474 C CB . GLN A 1 812 ? 35.897 51.194 -13.971 1.00 13.21 ? 812 GLN A CB 1 ATOM 6475 C CG . GLN A 1 812 ? 35.279 51.710 -12.637 1.00 16.53 ? 812 GLN A CG 1 ATOM 6476 C CD . GLN A 1 812 ? 34.989 50.580 -11.645 1.00 18.60 ? 812 GLN A CD 1 ATOM 6477 O OE1 . GLN A 1 812 ? 34.068 49.806 -11.836 1.00 18.42 ? 812 GLN A OE1 1 ATOM 6478 N NE2 . GLN A 1 812 ? 35.777 50.504 -10.566 1.00 18.51 ? 812 GLN A NE2 1 ATOM 6479 N N . PHE A 1 813 ? 34.203 52.610 -16.249 1.00 11.56 ? 813 PHE A N 1 ATOM 6480 C CA . PHE A 1 813 ? 32.917 53.222 -16.579 1.00 11.72 ? 813 PHE A CA 1 ATOM 6481 C C . PHE A 1 813 ? 31.806 52.303 -16.124 1.00 12.55 ? 813 PHE A C 1 ATOM 6482 O O . PHE A 1 813 ? 31.832 51.064 -16.387 1.00 15.40 ? 813 PHE A O 1 ATOM 6483 C CB . PHE A 1 813 ? 32.843 53.507 -18.082 1.00 12.27 ? 813 PHE A CB 1 ATOM 6484 C CG . PHE A 1 813 ? 33.602 54.738 -18.466 1.00 11.08 ? 813 PHE A CG 1 ATOM 6485 C CD1 . PHE A 1 813 ? 34.973 54.719 -18.550 1.00 11.31 ? 813 PHE A CD1 1 ATOM 6486 C CD2 . PHE A 1 813 ? 32.908 55.945 -18.663 1.00 12.40 ? 813 PHE A CD2 1 ATOM 6487 C CE1 . PHE A 1 813 ? 35.692 55.923 -18.807 1.00 12.59 ? 813 PHE A CE1 1 ATOM 6488 C CE2 . PHE A 1 813 ? 33.610 57.133 -18.921 1.00 14.78 ? 813 PHE A CE2 1 ATOM 6489 C CZ . PHE A 1 813 ? 35.007 57.095 -18.986 1.00 13.64 ? 813 PHE A CZ 1 ATOM 6490 N N . ILE A 1 814 ? 30.843 52.887 -15.425 1.00 11.97 ? 814 ILE A N 1 ATOM 6491 C CA . ILE A 1 814 ? 29.718 52.127 -14.911 1.00 12.87 ? 814 ILE A CA 1 ATOM 6492 C C . ILE A 1 814 ? 28.404 52.560 -15.600 1.00 13.08 ? 814 ILE A C 1 ATOM 6493 O O . ILE A 1 814 ? 28.180 53.745 -15.890 1.00 12.14 ? 814 ILE A O 1 ATOM 6494 C CB . ILE A 1 814 ? 29.650 52.320 -13.365 1.00 12.09 ? 814 ILE A CB 1 ATOM 6495 C CG1 . ILE A 1 814 ? 28.607 51.371 -12.770 1.00 11.65 ? 814 ILE A CG1 1 ATOM 6496 C CG2 . ILE A 1 814 ? 29.420 53.776 -12.978 1.00 13.20 ? 814 ILE A CG2 1 ATOM 6497 C CD1 . ILE A 1 814 ? 28.784 51.216 -11.206 1.00 11.72 ? 814 ILE A CD1 1 ATOM 6498 N N . LYS A 1 815 ? 27.560 51.554 -15.881 1.00 12.85 ? 815 LYS A N 1 ATOM 6499 C CA . LYS A 1 815 ? 26.257 51.834 -16.476 1.00 12.80 ? 815 LYS A CA 1 ATOM 6500 C C . LYS A 1 815 ? 25.334 52.463 -15.449 1.00 12.94 ? 815 LYS A C 1 ATOM 6501 O O . LYS A 1 815 ? 25.191 51.988 -14.312 1.00 12.98 ? 815 LYS A O 1 ATOM 6502 C CB . LYS A 1 815 ? 25.656 50.520 -16.981 1.00 13.65 ? 815 LYS A CB 1 ATOM 6503 C CG . LYS A 1 815 ? 24.382 50.661 -17.791 1.00 15.39 ? 815 LYS A CG 1 ATOM 6504 C CD . LYS A 1 815 ? 24.001 49.269 -18.325 1.00 18.76 ? 815 LYS A CD 1 ATOM 6505 C CE . LYS A 1 815 ? 22.745 49.290 -19.158 1.00 25.65 ? 815 LYS A CE 1 ATOM 6506 N NZ . LYS A 1 815 ? 22.518 47.919 -19.730 1.00 27.52 ? 815 LYS A NZ 1 ATOM 6507 N N . ARG A 1 816 ? 24.715 53.552 -15.846 1.00 12.40 ? 816 ARG A N 1 ATOM 6508 C CA . ARG A 1 816 ? 23.723 54.231 -15.040 1.00 11.70 ? 816 ARG A CA 1 ATOM 6509 C C . ARG A 1 816 ? 22.364 54.127 -15.741 1.00 12.15 ? 816 ARG A C 1 ATOM 6510 O O . ARG A 1 816 ? 22.302 54.077 -16.967 1.00 13.50 ? 816 ARG A O 1 ATOM 6511 C CB . ARG A 1 816 ? 23.997 55.739 -14.923 1.00 12.77 ? 816 ARG A CB 1 ATOM 6512 C CG . ARG A 1 816 ? 25.403 56.127 -14.433 1.00 14.28 ? 816 ARG A CG 1 ATOM 6513 C CD . ARG A 1 816 ? 25.637 55.511 -13.069 1.00 13.68 ? 816 ARG A CD 1 ATOM 6514 N NE . ARG A 1 816 ? 26.836 56.069 -12.449 1.00 12.43 ? 816 ARG A NE 1 ATOM 6515 C CZ . ARG A 1 816 ? 27.233 55.673 -11.238 1.00 12.34 ? 816 ARG A CZ 1 ATOM 6516 N NH1 . ARG A 1 816 ? 26.536 54.743 -10.603 1.00 11.79 ? 816 ARG A NH1 1 ATOM 6517 N NH2 . ARG A 1 816 ? 28.249 56.269 -10.619 1.00 11.84 ? 816 ARG A NH2 1 ATOM 6518 N N . ARG A 1 817 ? 21.303 54.088 -14.941 1.00 13.05 ? 817 ARG A N 1 ATOM 6519 C CA . ARG A 1 817 ? 19.955 54.112 -15.520 1.00 13.54 ? 817 ARG A CA 1 ATOM 6520 C C . ARG A 1 817 ? 19.218 55.250 -14.847 1.00 14.50 ? 817 ARG A C 1 ATOM 6521 O O . ARG A 1 817 ? 19.098 55.321 -13.602 1.00 15.13 ? 817 ARG A O 1 ATOM 6522 C CB . ARG A 1 817 ? 19.239 52.776 -15.252 1.00 15.09 ? 817 ARG A CB 1 ATOM 6523 C CG . ARG A 1 817 ? 17.778 52.788 -15.717 1.00 16.21 ? 817 ARG A CG 1 ATOM 6524 C CD . ARG A 1 817 ? 17.070 51.416 -15.512 1.00 17.07 ? 817 ARG A CD 1 ATOM 6525 N NE . ARG A 1 817 ? 17.618 50.399 -16.402 1.00 17.75 ? 817 ARG A NE 1 ATOM 6526 C CZ . ARG A 1 817 ? 18.387 49.387 -16.006 1.00 18.09 ? 817 ARG A CZ 1 ATOM 6527 N NH1 . ARG A 1 817 ? 18.710 49.258 -14.718 1.00 17.10 ? 817 ARG A NH1 1 ATOM 6528 N NH2 . ARG A 1 817 ? 18.828 48.494 -16.878 1.00 22.53 ? 817 ARG A NH2 1 ATOM 6529 N N . ARG A 1 818 ? 18.750 56.195 -15.669 1.00 13.19 ? 818 ARG A N 1 ATOM 6530 C CA . ARG A 1 818 ? 17.977 57.306 -15.145 1.00 14.92 ? 818 ARG A CA 1 ATOM 6531 C C . ARG A 1 818 ? 16.701 56.681 -14.607 1.00 16.34 ? 818 ARG A C 1 ATOM 6532 O O . ARG A 1 818 ? 16.074 55.848 -15.289 1.00 17.57 ? 818 ARG A O 1 ATOM 6533 C CB . ARG A 1 818 ? 17.600 58.292 -16.264 1.00 16.13 ? 818 ARG A CB 1 ATOM 6534 C CG A ARG A 1 818 ? 16.850 59.537 -15.763 0.50 15.17 ? 818 ARG A CG 1 ATOM 6535 C CG B ARG A 1 818 ? 16.983 59.524 -15.969 0.50 19.71 ? 818 ARG A CG 1 ATOM 6536 C CD A ARG A 1 818 ? 16.141 60.289 -16.910 0.50 12.90 ? 818 ARG A CD 1 ATOM 6537 C CD B ARG A 1 818 ? 16.803 60.425 -17.198 0.50 20.38 ? 818 ARG A CD 1 ATOM 6538 N NE A ARG A 1 818 ? 14.889 59.644 -17.266 0.50 14.45 ? 818 ARG A NE 1 ATOM 6539 N NE B ARG A 1 818 ? 16.045 59.779 -18.246 0.50 21.95 ? 818 ARG A NE 1 ATOM 6540 C CZ A ARG A 1 818 ? 14.627 59.078 -18.438 0.50 14.51 ? 818 ARG A CZ 1 ATOM 6541 C CZ B ARG A 1 818 ? 16.533 59.376 -19.416 0.50 19.39 ? 818 ARG A CZ 1 ATOM 6542 N NH1 A ARG A 1 818 ? 15.527 59.069 -19.406 0.50 12.49 ? 818 ARG A NH1 1 ATOM 6543 N NH1 B ARG A 1 818 ? 17.833 59.543 -19.752 0.50 15.27 ? 818 ARG A NH1 1 ATOM 6544 N NH2 A ARG A 1 818 ? 13.457 58.503 -18.626 0.50 17.46 ? 818 ARG A NH2 1 ATOM 6545 N NH2 B ARG A 1 818 ? 15.692 58.790 -20.255 0.50 19.30 ? 818 ARG A NH2 1 ATOM 6546 N N . LEU A 1 819 ? 16.314 57.087 -13.411 1.00 15.24 ? 819 LEU A N 1 ATOM 6547 C CA . LEU A 1 819 ? 15.087 56.558 -12.764 1.00 15.82 ? 819 LEU A CA 1 ATOM 6548 C C . LEU A 1 819 ? 14.114 57.717 -12.497 1.00 15.50 ? 819 LEU A C 1 ATOM 6549 O O . LEU A 1 819 ? 14.355 58.587 -11.649 1.00 16.90 ? 819 LEU A O 1 ATOM 6550 C CB . LEU A 1 819 ? 15.452 55.884 -11.432 1.00 16.52 ? 819 LEU A CB 1 ATOM 6551 C CG . LEU A 1 819 ? 16.393 54.671 -11.577 1.00 17.87 ? 819 LEU A CG 1 ATOM 6552 C CD1 . LEU A 1 819 ? 16.825 54.191 -10.197 1.00 21.22 ? 819 LEU A CD1 1 ATOM 6553 C CD2 . LEU A 1 819 ? 15.699 53.554 -12.326 1.00 19.08 ? 819 LEU A CD2 1 ATOM 6554 N N . ASP A 1 820 ? 13.003 57.714 -13.217 1.00 18.87 ? 820 ASP A N 1 ATOM 6555 C CA . ASP A 1 820 ? 12.063 58.780 -12.996 1.00 19.57 ? 820 ASP A CA 1 ATOM 6556 C C . ASP A 1 820 ? 11.357 58.649 -11.647 1.00 18.01 ? 820 ASP A C 1 ATOM 6557 O O . ASP A 1 820 ? 10.727 59.601 -11.173 1.00 19.94 ? 820 ASP A O 1 ATOM 6558 C CB . ASP A 1 820 ? 11.097 58.834 -14.179 1.00 21.16 ? 820 ASP A CB 1 ATOM 6559 C CG . ASP A 1 820 ? 11.816 59.159 -15.479 1.00 23.93 ? 820 ASP A CG 1 ATOM 6560 O OD1 . ASP A 1 820 ? 12.896 59.818 -15.450 1.00 24.89 ? 820 ASP A OD1 1 ATOM 6561 O OD2 . ASP A 1 820 ? 11.306 58.776 -16.552 1.00 27.41 ? 820 ASP A OD2 1 ATOM 6562 N N . LYS A 1 821 ? 11.466 57.481 -11.000 1.00 16.68 ? 821 LYS A N 1 ATOM 6563 C CA . LYS A 1 821 ? 10.869 57.347 -9.673 1.00 17.87 ? 821 LYS A CA 1 ATOM 6564 C C . LYS A 1 821 ? 11.715 58.087 -8.621 1.00 18.63 ? 821 LYS A C 1 ATOM 6565 O O . LYS A 1 821 ? 11.262 58.281 -7.499 1.00 21.60 ? 821 LYS A O 1 ATOM 6566 C CB . LYS A 1 821 ? 10.717 55.875 -9.280 1.00 18.30 ? 821 LYS A CB 1 ATOM 6567 C CG . LYS A 1 821 ? 12.047 55.168 -9.018 1.00 16.93 ? 821 LYS A CG 1 ATOM 6568 C CD . LYS A 1 821 ? 11.886 53.678 -8.994 1.00 18.84 ? 821 LYS A CD 1 ATOM 6569 C CE . LYS A 1 821 ? 13.206 52.991 -8.768 1.00 19.51 ? 821 LYS A CE 1 ATOM 6570 N NZ . LYS A 1 821 ? 13.133 51.526 -8.989 1.00 19.34 ? 821 LYS A NZ 1 ATOM 6571 N N . LEU A 1 822 ? 12.886 58.587 -9.031 1.00 16.56 ? 822 LEU A N 1 ATOM 6572 C CA . LEU A 1 822 ? 13.731 59.357 -8.084 1.00 18.22 ? 822 LEU A CA 1 ATOM 6573 C C . LEU A 1 822 ? 13.753 60.803 -8.595 1.00 18.36 ? 822 LEU A C 1 ATOM 6574 O O . LEU A 1 822 ? 13.581 61.030 -9.793 1.00 17.08 ? 822 LEU A O 1 ATOM 6575 C CB . LEU A 1 822 ? 15.183 58.826 -8.067 1.00 18.27 ? 822 LEU A CB 1 ATOM 6576 C CG . LEU A 1 822 ? 15.333 57.361 -7.614 1.00 18.93 ? 822 LEU A CG 1 ATOM 6577 C CD1 . LEU A 1 822 ? 16.810 56.983 -7.570 1.00 19.72 ? 822 LEU A CD1 1 ATOM 6578 C CD2 . LEU A 1 822 ? 14.651 57.136 -6.266 1.00 19.63 ? 822 LEU A CD2 1 ATOM 6579 N N . PRO A 1 823 ? 13.984 61.770 -7.695 1.00 16.73 ? 823 PRO A N 1 ATOM 6580 C CA . PRO A 1 823 ? 14.035 63.192 -8.104 1.00 17.23 ? 823 PRO A CA 1 ATOM 6581 C C . PRO A 1 823 ? 15.261 63.473 -8.964 1.00 18.25 ? 823 PRO A C 1 ATOM 6582 O O . PRO A 1 823 ? 16.235 62.698 -8.986 1.00 17.07 ? 823 PRO A O 1 ATOM 6583 C CB . PRO A 1 823 ? 14.061 63.955 -6.796 1.00 17.77 ? 823 PRO A CB 1 ATOM 6584 C CG . PRO A 1 823 ? 14.712 63.000 -5.814 1.00 19.10 ? 823 PRO A CG 1 ATOM 6585 C CD . PRO A 1 823 ? 14.178 61.611 -6.244 1.00 17.50 ? 823 PRO A CD 1 ATOM 6586 N N . LEU A 1 824 ? 15.210 64.584 -9.688 1.00 16.52 ? 824 LEU A N 1 ATOM 6587 C CA . LEU A 1 824 ? 16.278 64.965 -10.579 1.00 15.90 ? 824 LEU A CA 1 ATOM 6588 C C . LEU A 1 824 ? 17.688 64.840 -9.978 1.00 15.30 ? 824 LEU A C 1 ATOM 6589 O O . LEU A 1 824 ? 18.575 64.261 -10.626 1.00 14.52 ? 824 LEU A O 1 ATOM 6590 C CB . LEU A 1 824 ? 15.969 66.406 -11.053 1.00 16.79 ? 824 LEU A CB 1 ATOM 6591 C CG . LEU A 1 824 ? 16.763 66.990 -12.221 1.00 15.90 ? 824 LEU A CG 1 ATOM 6592 C CD1 . LEU A 1 824 ? 15.945 68.258 -12.701 1.00 16.86 ? 824 LEU A CD1 1 ATOM 6593 C CD2 . LEU A 1 824 ? 18.225 67.396 -11.831 1.00 16.12 ? 824 LEU A CD2 1 ATOM 6594 N N . GLN A 1 825 ? 17.869 65.385 -8.777 1.00 14.29 ? 825 GLN A N 1 ATOM 6595 C CA . GLN A 1 825 ? 19.180 65.386 -8.140 1.00 14.56 ? 825 GLN A CA 1 ATOM 6596 C C . GLN A 1 825 ? 19.715 63.990 -7.852 1.00 15.14 ? 825 GLN A C 1 ATOM 6597 O O . GLN A 1 825 ? 20.953 63.828 -7.725 1.00 13.86 ? 825 GLN A O 1 ATOM 6598 C CB . GLN A 1 825 ? 19.152 66.254 -6.885 1.00 14.36 ? 825 GLN A CB 1 ATOM 6599 C CG . GLN A 1 825 ? 18.226 65.717 -5.786 1.00 13.61 ? 825 GLN A CG 1 ATOM 6600 C CD . GLN A 1 825 ? 16.770 66.239 -5.886 1.00 14.26 ? 825 GLN A CD 1 ATOM 6601 O OE1 . GLN A 1 825 ? 16.318 66.679 -6.939 1.00 17.53 ? 825 GLN A OE1 1 ATOM 6602 N NE2 . GLN A 1 825 ? 16.049 66.166 -4.778 1.00 15.57 ? 825 GLN A NE2 1 ATOM 6603 N N . ALA A 1 826 ? 18.814 62.996 -7.748 1.00 14.50 ? 826 ALA A N 1 ATOM 6604 C CA . ALA A 1 826 ? 19.288 61.636 -7.506 1.00 13.66 ? 826 ALA A CA 1 ATOM 6605 C C . ALA A 1 826 ? 19.873 61.048 -8.777 1.00 13.85 ? 826 ALA A C 1 ATOM 6606 O O . ALA A 1 826 ? 20.624 60.073 -8.731 1.00 14.94 ? 826 ALA A O 1 ATOM 6607 C CB . ALA A 1 826 ? 18.134 60.754 -7.017 1.00 15.50 ? 826 ALA A CB 1 ATOM 6608 N N . ASN A 1 827 ? 19.513 61.599 -9.949 1.00 12.85 ? 827 ASN A N 1 ATOM 6609 C CA . ASN A 1 827 ? 20.006 61.115 -11.229 1.00 12.79 ? 827 ASN A CA 1 ATOM 6610 C C . ASN A 1 827 ? 21.308 61.782 -11.663 1.00 12.16 ? 827 ASN A C 1 ATOM 6611 O O . ASN A 1 827 ? 21.853 61.471 -12.710 1.00 13.32 ? 827 ASN A O 1 ATOM 6612 C CB . ASN A 1 827 ? 18.913 61.229 -12.302 1.00 14.32 ? 827 ASN A CB 1 ATOM 6613 C CG . ASN A 1 827 ? 17.794 60.215 -12.050 1.00 16.29 ? 827 ASN A CG 1 ATOM 6614 O OD1 . ASN A 1 827 ? 18.009 59.012 -12.115 1.00 15.85 ? 827 ASN A OD1 1 ATOM 6615 N ND2 . ASN A 1 827 ? 16.620 60.709 -11.709 1.00 18.15 ? 827 ASN A ND2 1 ATOM 6616 N N . TYR A 1 828 ? 21.827 62.630 -10.785 1.00 14.37 ? 828 TYR A N 1 ATOM 6617 C CA . TYR A 1 828 ? 23.146 63.229 -11.018 1.00 12.51 ? 828 TYR A CA 1 ATOM 6618 C C . TYR A 1 828 ? 24.182 62.294 -10.372 1.00 13.55 ? 828 TYR A C 1 ATOM 6619 O O . TYR A 1 828 ? 23.968 61.766 -9.281 1.00 14.55 ? 828 TYR A O 1 ATOM 6620 C CB . TYR A 1 828 ? 23.253 64.585 -10.320 1.00 13.55 ? 828 TYR A CB 1 ATOM 6621 C CG . TYR A 1 828 ? 23.233 65.733 -11.280 1.00 13.35 ? 828 TYR A CG 1 ATOM 6622 C CD1 . TYR A 1 828 ? 22.163 65.932 -12.167 1.00 11.87 ? 828 TYR A CD1 1 ATOM 6623 C CD2 . TYR A 1 828 ? 24.326 66.574 -11.374 1.00 13.65 ? 828 TYR A CD2 1 ATOM 6624 C CE1 . TYR A 1 828 ? 22.201 66.927 -13.140 1.00 13.84 ? 828 TYR A CE1 1 ATOM 6625 C CE2 . TYR A 1 828 ? 24.378 67.559 -12.304 1.00 15.71 ? 828 TYR A CE2 1 ATOM 6626 C CZ . TYR A 1 828 ? 23.319 67.734 -13.196 1.00 13.56 ? 828 TYR A CZ 1 ATOM 6627 O OH . TYR A 1 828 ? 23.465 68.754 -14.109 1.00 15.40 ? 828 TYR A OH 1 ATOM 6628 N N . TYR A 1 829 ? 25.283 62.103 -11.075 1.00 12.49 ? 829 TYR A N 1 ATOM 6629 C CA . TYR A 1 829 ? 26.367 61.217 -10.667 1.00 12.76 ? 829 TYR A CA 1 ATOM 6630 C C . TYR A 1 829 ? 27.703 61.939 -10.816 1.00 12.66 ? 829 TYR A C 1 ATOM 6631 O O . TYR A 1 829 ? 27.800 62.955 -11.474 1.00 12.75 ? 829 TYR A O 1 ATOM 6632 C CB . TYR A 1 829 ? 26.391 59.979 -11.584 1.00 11.44 ? 829 TYR A CB 1 ATOM 6633 C CG . TYR A 1 829 ? 25.253 59.074 -11.264 1.00 12.55 ? 829 TYR A CG 1 ATOM 6634 C CD1 . TYR A 1 829 ? 25.329 58.176 -10.197 1.00 12.10 ? 829 TYR A CD1 1 ATOM 6635 C CD2 . TYR A 1 829 ? 24.074 59.133 -12.021 1.00 13.31 ? 829 TYR A CD2 1 ATOM 6636 C CE1 . TYR A 1 829 ? 24.225 57.347 -9.872 1.00 14.43 ? 829 TYR A CE1 1 ATOM 6637 C CE2 . TYR A 1 829 ? 22.992 58.302 -11.708 1.00 14.01 ? 829 TYR A CE2 1 ATOM 6638 C CZ . TYR A 1 829 ? 23.066 57.416 -10.638 1.00 14.15 ? 829 TYR A CZ 1 ATOM 6639 O OH . TYR A 1 829 ? 21.968 56.597 -10.332 1.00 14.67 ? 829 TYR A OH 1 ATOM 6640 N N . PRO A 1 830 ? 28.749 61.429 -10.159 1.00 12.77 ? 830 PRO A N 1 ATOM 6641 C CA . PRO A 1 830 ? 30.055 62.088 -10.323 1.00 11.56 ? 830 PRO A CA 1 ATOM 6642 C C . PRO A 1 830 ? 30.541 61.843 -11.759 1.00 12.08 ? 830 PRO A C 1 ATOM 6643 O O . PRO A 1 830 ? 30.313 60.747 -12.315 1.00 12.59 ? 830 PRO A O 1 ATOM 6644 C CB . PRO A 1 830 ? 30.981 61.326 -9.316 1.00 16.27 ? 830 PRO A CB 1 ATOM 6645 C CG . PRO A 1 830 ? 30.057 60.478 -8.425 1.00 15.61 ? 830 PRO A CG 1 ATOM 6646 C CD . PRO A 1 830 ? 28.739 60.302 -9.204 1.00 13.56 ? 830 PRO A CD 1 ATOM 6647 N N . ILE A 1 831 ? 31.150 62.854 -12.377 1.00 12.76 ? 831 ILE A N 1 ATOM 6648 C CA . ILE A 1 831 ? 31.790 62.685 -13.680 1.00 12.03 ? 831 ILE A CA 1 ATOM 6649 C C . ILE A 1 831 ? 33.251 63.004 -13.391 1.00 12.62 ? 831 ILE A C 1 ATOM 6650 O O . ILE A 1 831 ? 33.767 64.075 -13.717 1.00 12.04 ? 831 ILE A O 1 ATOM 6651 C CB . ILE A 1 831 ? 31.226 63.669 -14.752 1.00 11.44 ? 831 ILE A CB 1 ATOM 6652 C CG1 . ILE A 1 831 ? 29.709 63.707 -14.715 1.00 12.45 ? 831 ILE A CG1 1 ATOM 6653 C CG2 . ILE A 1 831 ? 31.742 63.244 -16.160 1.00 13.58 ? 831 ILE A CG2 1 ATOM 6654 C CD1 . ILE A 1 831 ? 28.954 62.416 -15.051 1.00 11.81 ? 831 ILE A CD1 1 ATOM 6655 N N . PRO A 1 832 ? 33.968 62.050 -12.788 1.00 10.59 ? 832 PRO A N 1 ATOM 6656 C CA . PRO A 1 832 ? 35.365 62.379 -12.475 1.00 11.35 ? 832 PRO A CA 1 ATOM 6657 C C . PRO A 1 832 ? 36.271 62.503 -13.685 1.00 12.10 ? 832 PRO A C 1 ATOM 6658 O O . PRO A 1 832 ? 37.242 63.235 -13.596 1.00 15.06 ? 832 PRO A O 1 ATOM 6659 C CB . PRO A 1 832 ? 35.793 61.283 -11.489 1.00 11.52 ? 832 PRO A CB 1 ATOM 6660 C CG . PRO A 1 832 ? 34.786 60.182 -11.704 1.00 12.71 ? 832 PRO A CG 1 ATOM 6661 C CD . PRO A 1 832 ? 33.491 60.860 -12.076 1.00 12.42 ? 832 PRO A CD 1 ATOM 6662 N N . SER A 1 833 ? 35.934 61.855 -14.803 1.00 11.38 ? 833 SER A N 1 ATOM 6663 C CA . SER A 1 833 ? 36.790 62.020 -15.973 1.00 11.18 ? 833 SER A CA 1 ATOM 6664 C C . SER A 1 833 ? 36.002 61.813 -17.282 1.00 12.19 ? 833 SER A C 1 ATOM 6665 O O . SER A 1 833 ? 36.535 62.139 -18.335 1.00 11.29 ? 833 SER A O 1 ATOM 6666 C CB . SER A 1 833 ? 37.985 61.062 -15.921 1.00 12.99 ? 833 SER A CB 1 ATOM 6667 O OG . SER A 1 833 ? 37.648 59.728 -16.208 1.00 15.72 ? 833 SER A OG 1 ATOM 6668 N N . GLY A 1 834 ? 34.784 61.264 -17.243 1.00 11.62 ? 834 GLY A N 1 ATOM 6669 C CA . GLY A 1 834 ? 34.079 61.134 -18.545 1.00 12.00 ? 834 GLY A CA 1 ATOM 6670 C C . GLY A 1 834 ? 32.715 60.529 -18.408 1.00 10.51 ? 834 GLY A C 1 ATOM 6671 O O . GLY A 1 834 ? 32.330 59.946 -17.385 1.00 11.97 ? 834 GLY A O 1 ATOM 6672 N N . MET A 1 835 ? 31.939 60.685 -19.477 1.00 12.01 ? 835 MET A N 1 ATOM 6673 C CA . MET A 1 835 ? 30.578 60.135 -19.494 1.00 11.89 ? 835 MET A CA 1 ATOM 6674 C C . MET A 1 835 ? 30.215 59.911 -20.965 1.00 12.65 ? 835 MET A C 1 ATOM 6675 O O . MET A 1 835 ? 30.822 60.543 -21.872 1.00 13.28 ? 835 MET A O 1 ATOM 6676 C CB . MET A 1 835 ? 29.596 61.137 -18.855 1.00 12.19 ? 835 MET A CB 1 ATOM 6677 C CG . MET A 1 835 ? 29.517 62.476 -19.619 1.00 14.93 ? 835 MET A CG 1 ATOM 6678 S SD . MET A 1 835 ? 28.605 63.761 -18.771 1.00 15.95 ? 835 MET A SD 1 ATOM 6679 C CE . MET A 1 835 ? 27.134 62.965 -18.289 1.00 18.96 ? 835 MET A CE 1 ATOM 6680 N N . PHE A 1 836 ? 29.286 58.997 -21.200 1.00 11.76 ? 836 PHE A N 1 ATOM 6681 C CA . PHE A 1 836 ? 28.854 58.793 -22.593 1.00 11.88 ? 836 PHE A CA 1 ATOM 6682 C C . PHE A 1 836 ? 27.466 58.243 -22.673 1.00 13.98 ? 836 PHE A C 1 ATOM 6683 O O . PHE A 1 836 ? 26.919 57.712 -21.715 1.00 13.95 ? 836 PHE A O 1 ATOM 6684 C CB . PHE A 1 836 ? 29.872 57.927 -23.403 1.00 13.09 ? 836 PHE A CB 1 ATOM 6685 C CG . PHE A 1 836 ? 30.040 56.484 -22.945 1.00 13.32 ? 836 PHE A CG 1 ATOM 6686 C CD1 . PHE A 1 836 ? 29.173 55.474 -23.392 1.00 13.55 ? 836 PHE A CD1 1 ATOM 6687 C CD2 . PHE A 1 836 ? 31.131 56.123 -22.156 1.00 13.22 ? 836 PHE A CD2 1 ATOM 6688 C CE1 . PHE A 1 836 ? 29.405 54.128 -23.063 1.00 14.55 ? 836 PHE A CE1 1 ATOM 6689 C CE2 . PHE A 1 836 ? 31.359 54.775 -21.831 1.00 14.88 ? 836 PHE A CE2 1 ATOM 6690 C CZ . PHE A 1 836 ? 30.501 53.780 -22.291 1.00 15.36 ? 836 PHE A CZ 1 ATOM 6691 N N . ILE A 1 837 ? 26.858 58.446 -23.850 1.00 14.11 ? 837 ILE A N 1 ATOM 6692 C CA . ILE A 1 837 ? 25.545 57.857 -24.164 1.00 14.56 ? 837 ILE A CA 1 ATOM 6693 C C . ILE A 1 837 ? 25.724 57.169 -25.501 1.00 13.35 ? 837 ILE A C 1 ATOM 6694 O O . ILE A 1 837 ? 26.578 57.559 -26.307 1.00 13.92 ? 837 ILE A O 1 ATOM 6695 C CB . ILE A 1 837 ? 24.412 58.905 -24.289 1.00 14.87 ? 837 ILE A CB 1 ATOM 6696 C CG1 . ILE A 1 837 ? 24.878 60.109 -25.107 1.00 15.12 ? 837 ILE A CG1 1 ATOM 6697 C CG2 . ILE A 1 837 ? 23.818 59.227 -22.925 1.00 15.68 ? 837 ILE A CG2 1 ATOM 6698 C CD1 . ILE A 1 837 ? 23.641 60.967 -25.607 1.00 16.40 ? 837 ILE A CD1 1 ATOM 6699 N N . GLU A 1 838 ? 24.935 56.123 -25.729 1.00 12.97 ? 838 GLU A N 1 ATOM 6700 C CA . GLU A 1 838 ? 25.034 55.433 -27.015 1.00 15.36 ? 838 GLU A CA 1 ATOM 6701 C C . GLU A 1 838 ? 23.754 54.702 -27.357 1.00 14.57 ? 838 GLU A C 1 ATOM 6702 O O . GLU A 1 838 ? 22.876 54.504 -26.539 1.00 15.06 ? 838 GLU A O 1 ATOM 6703 C CB . GLU A 1 838 ? 26.158 54.398 -27.015 1.00 15.74 ? 838 GLU A CB 1 ATOM 6704 C CG . GLU A 1 838 ? 25.937 53.265 -25.982 1.00 16.36 ? 838 GLU A CG 1 ATOM 6705 C CD . GLU A 1 838 ? 27.054 52.204 -25.965 1.00 19.17 ? 838 GLU A CD 1 ATOM 6706 O OE1 . GLU A 1 838 ? 28.061 52.337 -26.675 1.00 18.62 ? 838 GLU A OE1 1 ATOM 6707 O OE2 . GLU A 1 838 ? 26.901 51.186 -25.243 1.00 20.97 ? 838 GLU A OE2 1 ATOM 6708 N N . ASP A 1 839 ? 23.637 54.393 -28.649 1.00 16.12 ? 839 ASP A N 1 ATOM 6709 C CA . ASP A 1 839 ? 22.535 53.525 -29.101 1.00 16.48 ? 839 ASP A CA 1 ATOM 6710 C C . ASP A 1 839 ? 23.230 52.443 -29.905 1.00 17.30 ? 839 ASP A C 1 ATOM 6711 O O . ASP A 1 839 ? 24.429 52.232 -29.776 1.00 18.58 ? 839 ASP A O 1 ATOM 6712 C CB . ASP A 1 839 ? 21.432 54.248 -29.907 1.00 15.66 ? 839 ASP A CB 1 ATOM 6713 C CG . ASP A 1 839 ? 21.937 54.982 -31.171 1.00 15.22 ? 839 ASP A CG 1 ATOM 6714 O OD1 . ASP A 1 839 ? 22.956 54.583 -31.758 1.00 18.21 ? 839 ASP A OD1 1 ATOM 6715 O OD2 . ASP A 1 839 ? 21.234 55.976 -31.512 1.00 21.33 ? 839 ASP A OD2 1 ATOM 6716 N N . ALA A 1 840 ? 22.490 51.714 -30.744 1.00 16.95 ? 840 ALA A N 1 ATOM 6717 C CA . ALA A 1 840 ? 23.117 50.654 -31.490 1.00 19.20 ? 840 ALA A CA 1 ATOM 6718 C C . ALA A 1 840 ? 24.220 51.100 -32.414 1.00 16.97 ? 840 ALA A C 1 ATOM 6719 O O . ALA A 1 840 ? 25.175 50.377 -32.659 1.00 19.56 ? 840 ALA A O 1 ATOM 6720 C CB . ALA A 1 840 ? 22.043 49.889 -32.318 1.00 20.41 ? 840 ALA A CB 1 ATOM 6721 N N . ASN A 1 841 ? 24.098 52.326 -32.918 1.00 17.99 ? 841 ASN A N 1 ATOM 6722 C CA . ASN A 1 841 ? 25.050 52.800 -33.899 1.00 17.53 ? 841 ASN A CA 1 ATOM 6723 C C . ASN A 1 841 ? 25.991 53.936 -33.563 1.00 15.55 ? 841 ASN A C 1 ATOM 6724 O O . ASN A 1 841 ? 27.052 54.031 -34.177 1.00 17.79 ? 841 ASN A O 1 ATOM 6725 C CB . ASN A 1 841 ? 24.293 53.239 -35.174 1.00 19.79 ? 841 ASN A CB 1 ATOM 6726 C CG . ASN A 1 841 ? 23.564 52.087 -35.864 1.00 21.77 ? 841 ASN A CG 1 ATOM 6727 O OD1 . ASN A 1 841 ? 24.095 50.988 -35.982 1.00 24.54 ? 841 ASN A OD1 1 ATOM 6728 N ND2 . ASN A 1 841 ? 22.365 52.363 -36.342 1.00 24.76 ? 841 ASN A ND2 1 ATOM 6729 N N . THR A 1 842 ? 25.583 54.789 -32.633 1.00 16.02 ? 842 THR A N 1 ATOM 6730 C CA . THR A 1 842 ? 26.335 55.996 -32.383 1.00 16.06 ? 842 THR A CA 1 ATOM 6731 C C . THR A 1 842 ? 26.598 56.185 -30.904 1.00 15.06 ? 842 THR A C 1 ATOM 6732 O O . THR A 1 842 ? 25.738 55.885 -30.079 1.00 16.88 ? 842 THR A O 1 ATOM 6733 C CB . THR A 1 842 ? 25.511 57.213 -32.878 1.00 17.66 ? 842 THR A CB 1 ATOM 6734 O OG1 . THR A 1 842 ? 25.073 57.000 -34.239 1.00 18.13 ? 842 THR A OG1 1 ATOM 6735 C CG2 . THR A 1 842 ? 26.354 58.472 -32.873 1.00 17.57 ? 842 THR A CG2 1 ATOM 6736 N N . ARG A 1 843 ? 27.768 56.732 -30.623 1.00 14.43 ? 843 ARG A N 1 ATOM 6737 C CA . ARG A 1 843 ? 28.144 57.059 -29.253 1.00 15.16 ? 843 ARG A CA 1 ATOM 6738 C C . ARG A 1 843 ? 28.707 58.483 -29.194 1.00 14.28 ? 843 ARG A C 1 ATOM 6739 O O . ARG A 1 843 ? 29.420 58.942 -30.131 1.00 15.40 ? 843 ARG A O 1 ATOM 6740 C CB . ARG A 1 843 ? 29.210 56.100 -28.742 1.00 15.93 ? 843 ARG A CB 1 ATOM 6741 C CG . ARG A 1 843 ? 29.589 56.403 -27.231 1.00 13.60 ? 843 ARG A CG 1 ATOM 6742 C CD . ARG A 1 843 ? 30.767 55.546 -26.814 1.00 13.89 ? 843 ARG A CD 1 ATOM 6743 N NE . ARG A 1 843 ? 30.390 54.156 -26.527 1.00 14.65 ? 843 ARG A NE 1 ATOM 6744 C CZ . ARG A 1 843 ? 31.206 53.317 -25.913 1.00 15.31 ? 843 ARG A CZ 1 ATOM 6745 N NH1 . ARG A 1 843 ? 32.425 53.718 -25.567 1.00 14.63 ? 843 ARG A NH1 1 ATOM 6746 N NH2 . ARG A 1 843 ? 30.761 52.111 -25.562 1.00 15.59 ? 843 ARG A NH2 1 ATOM 6747 N N . LEU A 1 844 ? 28.325 59.172 -28.127 1.00 13.42 ? 844 LEU A N 1 ATOM 6748 C CA . LEU A 1 844 ? 28.870 60.521 -27.849 1.00 13.04 ? 844 LEU A CA 1 ATOM 6749 C C . LEU A 1 844 ? 29.532 60.418 -26.466 1.00 12.46 ? 844 LEU A C 1 ATOM 6750 O O . LEU A 1 844 ? 28.837 60.109 -25.485 1.00 14.19 ? 844 LEU A O 1 ATOM 6751 C CB . LEU A 1 844 ? 27.793 61.612 -27.823 1.00 13.85 ? 844 LEU A CB 1 ATOM 6752 C CG . LEU A 1 844 ? 28.470 63.006 -27.702 1.00 15.01 ? 844 LEU A CG 1 ATOM 6753 C CD1 . LEU A 1 844 ? 29.360 63.321 -28.914 1.00 15.98 ? 844 LEU A CD1 1 ATOM 6754 C CD2 . LEU A 1 844 ? 27.404 64.084 -27.538 1.00 16.72 ? 844 LEU A CD2 1 ATOM 6755 N N . THR A 1 845 ? 30.826 60.734 -26.441 1.00 13.31 ? 845 THR A N 1 ATOM 6756 C CA . THR A 1 845 ? 31.600 60.659 -25.173 1.00 13.12 ? 845 THR A CA 1 ATOM 6757 C C . THR A 1 845 ? 32.152 62.036 -24.881 1.00 13.38 ? 845 THR A C 1 ATOM 6758 O O . THR A 1 845 ? 32.777 62.660 -25.758 1.00 13.17 ? 845 THR A O 1 ATOM 6759 C CB . THR A 1 845 ? 32.798 59.708 -25.282 1.00 11.34 ? 845 THR A CB 1 ATOM 6760 O OG1 . THR A 1 845 ? 32.329 58.400 -25.672 1.00 13.38 ? 845 THR A OG1 1 ATOM 6761 C CG2 . THR A 1 845 ? 33.443 59.517 -23.924 1.00 13.76 ? 845 THR A CG2 1 ATOM 6762 N N . LEU A 1 846 ? 31.939 62.493 -23.656 1.00 13.79 ? 846 LEU A N 1 ATOM 6763 C CA . LEU A 1 846 ? 32.459 63.786 -23.206 1.00 12.15 ? 846 LEU A CA 1 ATOM 6764 C C . LEU A 1 846 ? 33.514 63.450 -22.133 1.00 11.00 ? 846 LEU A C 1 ATOM 6765 O O . LEU A 1 846 ? 33.168 62.864 -21.086 1.00 12.18 ? 846 LEU A O 1 ATOM 6766 C CB . LEU A 1 846 ? 31.348 64.661 -22.598 1.00 15.11 ? 846 LEU A CB 1 ATOM 6767 C CG . LEU A 1 846 ? 31.808 66.045 -22.079 1.00 14.54 ? 846 LEU A CG 1 ATOM 6768 C CD1 . LEU A 1 846 ? 32.308 66.907 -23.275 1.00 14.90 ? 846 LEU A CD1 1 ATOM 6769 C CD2 . LEU A 1 846 ? 30.683 66.757 -21.336 1.00 17.16 ? 846 LEU A CD2 1 ATOM 6770 N N . LEU A 1 847 ? 34.780 63.752 -22.414 1.00 11.99 ? 847 LEU A N 1 ATOM 6771 C CA . LEU A 1 847 ? 35.859 63.515 -21.426 1.00 9.76 ? 847 LEU A CA 1 ATOM 6772 C C . LEU A 1 847 ? 36.107 64.837 -20.722 1.00 12.52 ? 847 LEU A C 1 ATOM 6773 O O . LEU A 1 847 ? 35.988 65.909 -21.335 1.00 12.74 ? 847 LEU A O 1 ATOM 6774 C CB . LEU A 1 847 ? 37.134 63.063 -22.098 1.00 11.58 ? 847 LEU A CB 1 ATOM 6775 C CG . LEU A 1 847 ? 37.168 61.720 -22.838 1.00 10.33 ? 847 LEU A CG 1 ATOM 6776 C CD1 . LEU A 1 847 ? 36.555 60.614 -21.958 1.00 12.86 ? 847 LEU A CD1 1 ATOM 6777 C CD2 . LEU A 1 847 ? 36.424 61.823 -24.170 1.00 12.53 ? 847 LEU A CD2 1 ATOM 6778 N N . THR A 1 848 ? 36.475 64.779 -19.445 1.00 11.15 ? 848 THR A N 1 ATOM 6779 C CA . THR A 1 848 ? 36.730 65.997 -18.654 1.00 11.61 ? 848 THR A CA 1 ATOM 6780 C C . THR A 1 848 ? 38.129 66.076 -18.040 1.00 13.78 ? 848 THR A C 1 ATOM 6781 O O . THR A 1 848 ? 38.793 65.051 -17.772 1.00 13.29 ? 848 THR A O 1 ATOM 6782 C CB . THR A 1 848 ? 35.739 66.095 -17.476 1.00 14.79 ? 848 THR A CB 1 ATOM 6783 O OG1 . THR A 1 848 ? 36.136 65.147 -16.447 1.00 17.01 ? 848 THR A OG1 1 ATOM 6784 C CG2 . THR A 1 848 ? 34.381 65.774 -17.889 1.00 14.94 ? 848 THR A CG2 1 ATOM 6785 N N . GLY A 1 849 ? 38.588 67.318 -17.896 1.00 11.59 ? 849 GLY A N 1 ATOM 6786 C CA . GLY A 1 849 ? 39.858 67.565 -17.238 1.00 11.60 ? 849 GLY A CA 1 ATOM 6787 C C . GLY A 1 849 ? 39.691 67.923 -15.782 1.00 10.89 ? 849 GLY A C 1 ATOM 6788 O O . GLY A 1 849 ? 40.642 68.378 -15.153 1.00 11.51 ? 849 GLY A O 1 ATOM 6789 N N . GLN A 1 850 ? 38.500 67.721 -15.237 1.00 11.56 ? 850 GLN A N 1 ATOM 6790 C CA . GLN A 1 850 ? 38.198 68.045 -13.851 1.00 10.36 ? 850 GLN A CA 1 ATOM 6791 C C . GLN A 1 850 ? 36.922 67.308 -13.456 1.00 10.73 ? 850 GLN A C 1 ATOM 6792 O O . GLN A 1 850 ? 36.021 67.106 -14.286 1.00 11.37 ? 850 GLN A O 1 ATOM 6793 C CB . GLN A 1 850 ? 37.978 69.578 -13.689 1.00 11.55 ? 850 GLN A CB 1 ATOM 6794 C CG . GLN A 1 850 ? 36.847 70.153 -14.628 1.00 11.61 ? 850 GLN A CG 1 ATOM 6795 C CD . GLN A 1 850 ? 37.204 70.223 -16.072 1.00 13.03 ? 850 GLN A CD 1 ATOM 6796 O OE1 . GLN A 1 850 ? 38.296 70.624 -16.448 1.00 13.54 ? 850 GLN A OE1 1 ATOM 6797 N NE2 . GLN A 1 850 ? 36.232 69.880 -16.933 1.00 11.40 ? 850 GLN A NE2 1 ATOM 6798 N N . PRO A 1 851 ? 36.809 66.895 -12.194 1.00 10.02 ? 851 PRO A N 1 ATOM 6799 C CA . PRO A 1 851 ? 35.577 66.198 -11.780 1.00 10.71 ? 851 PRO A CA 1 ATOM 6800 C C . PRO A 1 851 ? 34.452 67.181 -11.607 1.00 11.20 ? 851 PRO A C 1 ATOM 6801 O O . PRO A 1 851 ? 34.645 68.219 -10.955 1.00 11.59 ? 851 PRO A O 1 ATOM 6802 C CB . PRO A 1 851 ? 35.970 65.538 -10.443 1.00 11.41 ? 851 PRO A CB 1 ATOM 6803 C CG . PRO A 1 851 ? 37.058 66.492 -9.898 1.00 10.94 ? 851 PRO A CG 1 ATOM 6804 C CD . PRO A 1 851 ? 37.837 66.930 -11.129 1.00 10.39 ? 851 PRO A CD 1 ATOM 6805 N N . LEU A 1 852 ? 33.285 66.855 -12.186 1.00 10.77 ? 852 LEU A N 1 ATOM 6806 C CA . LEU A 1 852 ? 32.089 67.706 -12.070 1.00 13.10 ? 852 LEU A CA 1 ATOM 6807 C C . LEU A 1 852 ? 30.877 66.795 -11.959 1.00 13.91 ? 852 LEU A C 1 ATOM 6808 O O . LEU A 1 852 ? 31.009 65.595 -12.193 1.00 16.67 ? 852 LEU A O 1 ATOM 6809 C CB . LEU A 1 852 ? 31.948 68.603 -13.309 1.00 13.19 ? 852 LEU A CB 1 ATOM 6810 C CG . LEU A 1 852 ? 33.107 69.617 -13.453 1.00 12.44 ? 852 LEU A CG 1 ATOM 6811 C CD1 . LEU A 1 852 ? 33.064 70.195 -14.917 1.00 15.03 ? 852 LEU A CD1 1 ATOM 6812 C CD2 . LEU A 1 852 ? 33.035 70.748 -12.404 1.00 12.63 ? 852 LEU A CD2 1 ATOM 6813 N N . GLY A 1 853 ? 29.726 67.330 -11.598 1.00 11.68 ? 853 GLY A N 1 ATOM 6814 C CA . GLY A 1 853 ? 28.544 66.478 -11.551 1.00 12.01 ? 853 GLY A CA 1 ATOM 6815 C C . GLY A 1 853 ? 27.790 66.464 -12.867 1.00 11.82 ? 853 GLY A C 1 ATOM 6816 O O . GLY A 1 853 ? 27.832 67.454 -13.611 1.00 12.60 ? 853 GLY A O 1 ATOM 6817 N N . GLY A 1 854 ? 27.080 65.394 -13.164 1.00 10.95 ? 854 GLY A N 1 ATOM 6818 C CA . GLY A 1 854 ? 26.360 65.358 -14.434 1.00 12.80 ? 854 GLY A CA 1 ATOM 6819 C C . GLY A 1 854 ? 25.337 64.259 -14.536 1.00 11.36 ? 854 GLY A C 1 ATOM 6820 O O . GLY A 1 854 ? 25.166 63.418 -13.620 1.00 13.42 ? 854 GLY A O 1 ATOM 6821 N N . SER A 1 855 ? 24.666 64.220 -15.692 1.00 12.87 ? 855 SER A N 1 ATOM 6822 C CA . SER A 1 855 ? 23.606 63.231 -15.879 1.00 12.28 ? 855 SER A CA 1 ATOM 6823 C C . SER A 1 855 ? 23.205 63.187 -17.317 1.00 13.97 ? 855 SER A C 1 ATOM 6824 O O . SER A 1 855 ? 23.815 63.828 -18.156 1.00 14.79 ? 855 SER A O 1 ATOM 6825 C CB . SER A 1 855 ? 22.380 63.675 -15.068 1.00 14.13 ? 855 SER A CB 1 ATOM 6826 O OG . SER A 1 855 ? 21.364 62.670 -15.039 1.00 14.75 ? 855 SER A OG 1 ATOM 6827 N N . SER A 1 856 ? 22.194 62.355 -17.582 1.00 14.00 ? 856 SER A N 1 ATOM 6828 C CA . SER A 1 856 ? 21.536 62.292 -18.907 1.00 14.86 ? 856 SER A CA 1 ATOM 6829 C C . SER A 1 856 ? 20.075 62.286 -18.461 1.00 14.78 ? 856 SER A C 1 ATOM 6830 O O . SER A 1 856 ? 19.548 61.232 -18.073 1.00 16.37 ? 856 SER A O 1 ATOM 6831 C CB . SER A 1 856 ? 21.869 61.002 -19.629 1.00 14.24 ? 856 SER A CB 1 ATOM 6832 O OG . SER A 1 856 ? 21.091 60.962 -20.847 1.00 15.76 ? 856 SER A OG 1 ATOM 6833 N N . LEU A 1 857 ? 19.400 63.446 -18.502 1.00 15.61 ? 857 LEU A N 1 ATOM 6834 C CA . LEU A 1 857 ? 18.028 63.560 -17.982 1.00 14.30 ? 857 LEU A CA 1 ATOM 6835 C C . LEU A 1 857 ? 16.932 63.237 -18.989 1.00 16.41 ? 857 LEU A C 1 ATOM 6836 O O . LEU A 1 857 ? 15.767 63.185 -18.646 1.00 19.17 ? 857 LEU A O 1 ATOM 6837 C CB . LEU A 1 857 ? 17.809 64.963 -17.359 1.00 15.35 ? 857 LEU A CB 1 ATOM 6838 C CG . LEU A 1 857 ? 18.670 65.203 -16.126 1.00 16.75 ? 857 LEU A CG 1 ATOM 6839 C CD1 . LEU A 1 857 ? 18.473 66.647 -15.669 1.00 16.99 ? 857 LEU A CD1 1 ATOM 6840 C CD2 . LEU A 1 857 ? 18.270 64.242 -14.977 1.00 17.92 ? 857 LEU A CD2 1 ATOM 6841 N N . ALA A 1 858 ? 17.356 63.012 -20.201 1.00 14.87 ? 858 ALA A N 1 ATOM 6842 C CA . ALA A 1 858 ? 16.457 62.617 -21.298 1.00 15.46 ? 858 ALA A CA 1 ATOM 6843 C C . ALA A 1 858 ? 17.276 61.918 -22.356 1.00 17.36 ? 858 ALA A C 1 ATOM 6844 O O . ALA A 1 858 ? 18.479 62.142 -22.513 1.00 17.26 ? 858 ALA A O 1 ATOM 6845 C CB . ALA A 1 858 ? 15.749 63.845 -21.888 1.00 16.28 ? 858 ALA A CB 1 ATOM 6846 N N . SER A 1 859 ? 16.628 61.029 -23.103 1.00 16.29 ? 859 SER A N 1 ATOM 6847 C CA . SER A 1 859 ? 17.284 60.287 -24.153 1.00 14.72 ? 859 SER A CA 1 ATOM 6848 C C . SER A 1 859 ? 18.030 61.243 -25.085 1.00 16.27 ? 859 SER A C 1 ATOM 6849 O O . SER A 1 859 ? 17.496 62.291 -25.455 1.00 17.76 ? 859 SER A O 1 ATOM 6850 C CB . SER A 1 859 ? 16.227 59.444 -24.965 1.00 15.99 ? 859 SER A CB 1 ATOM 6851 O OG . SER A 1 859 ? 16.835 58.678 -25.963 1.00 18.15 ? 859 SER A OG 1 ATOM 6852 N N . GLY A 1 860 ? 19.246 60.874 -25.447 1.00 16.22 ? 860 GLY A N 1 ATOM 6853 C CA . GLY A 1 860 ? 20.039 61.689 -26.354 1.00 15.24 ? 860 GLY A CA 1 ATOM 6854 C C . GLY A 1 860 ? 20.774 62.842 -25.670 1.00 14.65 ? 860 GLY A C 1 ATOM 6855 O O . GLY A 1 860 ? 21.548 63.511 -26.374 1.00 14.80 ? 860 GLY A O 1 ATOM 6856 N N . GLU A 1 861 ? 20.612 63.053 -24.366 1.00 15.00 ? 861 GLU A N 1 ATOM 6857 C CA . GLU A 1 861 ? 21.296 64.158 -23.714 1.00 15.37 ? 861 GLU A CA 1 ATOM 6858 C C . GLU A 1 861 ? 22.437 63.759 -22.805 1.00 16.59 ? 861 GLU A C 1 ATOM 6859 O O . GLU A 1 861 ? 22.494 62.649 -22.250 1.00 15.91 ? 861 GLU A O 1 ATOM 6860 C CB . GLU A 1 861 ? 20.369 64.956 -22.816 1.00 17.01 ? 861 GLU A CB 1 ATOM 6861 C CG . GLU A 1 861 ? 19.208 65.588 -23.536 1.00 17.74 ? 861 GLU A CG 1 ATOM 6862 C CD . GLU A 1 861 ? 18.297 66.415 -22.630 1.00 18.56 ? 861 GLU A CD 1 ATOM 6863 O OE1 . GLU A 1 861 ? 18.458 66.481 -21.396 1.00 18.47 ? 861 GLU A OE1 1 ATOM 6864 O OE2 . GLU A 1 861 ? 17.329 67.030 -23.191 1.00 22.06 ? 861 GLU A OE2 1 ATOM 6865 N N . LEU A 1 862 ? 23.326 64.714 -22.650 1.00 14.05 ? 862 LEU A N 1 ATOM 6866 C CA . LEU A 1 862 ? 24.413 64.603 -21.645 1.00 13.78 ? 862 LEU A CA 1 ATOM 6867 C C . LEU A 1 862 ? 24.448 65.970 -21.022 1.00 13.65 ? 862 LEU A C 1 ATOM 6868 O O . LEU A 1 862 ? 24.271 66.976 -21.720 1.00 14.97 ? 862 LEU A O 1 ATOM 6869 C CB . LEU A 1 862 ? 25.806 64.334 -22.283 1.00 14.34 ? 862 LEU A CB 1 ATOM 6870 C CG . LEU A 1 862 ? 26.123 62.952 -22.902 1.00 15.02 ? 862 LEU A CG 1 ATOM 6871 C CD1 . LEU A 1 862 ? 27.478 62.974 -23.636 1.00 16.05 ? 862 LEU A CD1 1 ATOM 6872 C CD2 . LEU A 1 862 ? 26.081 61.914 -21.802 1.00 15.50 ? 862 LEU A CD2 1 ATOM 6873 N N . GLU A 1 863 ? 24.722 66.068 -19.733 1.00 12.69 ? 863 GLU A N 1 ATOM 6874 C CA . GLU A 1 863 ? 24.884 67.388 -19.139 1.00 11.75 ? 863 GLU A CA 1 ATOM 6875 C C . GLU A 1 863 ? 25.843 67.327 -17.989 1.00 13.26 ? 863 GLU A C 1 ATOM 6876 O O . GLU A 1 863 ? 25.976 66.295 -17.330 1.00 12.83 ? 863 GLU A O 1 ATOM 6877 C CB . GLU A 1 863 ? 23.566 68.024 -18.696 1.00 13.12 ? 863 GLU A CB 1 ATOM 6878 C CG . GLU A 1 863 ? 22.949 67.450 -17.439 1.00 14.58 ? 863 GLU A CG 1 ATOM 6879 C CD . GLU A 1 863 ? 21.666 68.203 -17.073 1.00 14.26 ? 863 GLU A CD 1 ATOM 6880 O OE1 . GLU A 1 863 ? 20.761 68.250 -17.948 1.00 16.60 ? 863 GLU A OE1 1 ATOM 6881 O OE2 . GLU A 1 863 ? 21.547 68.726 -15.958 1.00 15.27 ? 863 GLU A OE2 1 ATOM 6882 N N . ILE A 1 864 ? 26.558 68.432 -17.804 1.00 13.02 ? 864 ILE A N 1 ATOM 6883 C CA . ILE A 1 864 ? 27.596 68.475 -16.763 1.00 13.85 ? 864 ILE A CA 1 ATOM 6884 C C . ILE A 1 864 ? 27.611 69.872 -16.178 1.00 14.02 ? 864 ILE A C 1 ATOM 6885 O O . ILE A 1 864 ? 27.612 70.890 -16.904 1.00 14.14 ? 864 ILE A O 1 ATOM 6886 C CB . ILE A 1 864 ? 28.961 68.049 -17.362 1.00 12.83 ? 864 ILE A CB 1 ATOM 6887 C CG1 . ILE A 1 864 ? 30.036 67.967 -16.256 1.00 15.30 ? 864 ILE A CG1 1 ATOM 6888 C CG2 . ILE A 1 864 ? 29.386 68.976 -18.481 1.00 17.78 ? 864 ILE A CG2 1 ATOM 6889 C CD1 . ILE A 1 864 ? 31.196 67.082 -16.777 1.00 16.68 ? 864 ILE A CD1 1 ATOM 6890 N N . MET A 1 865 ? 27.567 69.920 -14.856 1.00 12.58 ? 865 MET A N 1 ATOM 6891 C CA . MET A 1 865 ? 27.509 71.190 -14.146 1.00 13.10 ? 865 MET A CA 1 ATOM 6892 C C . MET A 1 865 ? 28.886 71.901 -14.192 1.00 14.10 ? 865 MET A C 1 ATOM 6893 O O . MET A 1 865 ? 29.933 71.278 -14.005 1.00 13.40 ? 865 MET A O 1 ATOM 6894 C CB . MET A 1 865 ? 27.026 70.947 -12.696 1.00 12.46 ? 865 MET A CB 1 ATOM 6895 C CG . MET A 1 865 ? 26.440 72.175 -11.991 1.00 11.74 ? 865 MET A CG 1 ATOM 6896 S SD . MET A 1 865 ? 24.841 72.622 -12.763 1.00 15.44 ? 865 MET A SD 1 ATOM 6897 C CE . MET A 1 865 ? 23.825 71.422 -11.848 1.00 13.61 ? 865 MET A CE 1 ATOM 6898 N N . GLN A 1 866 ? 28.859 73.226 -14.413 1.00 13.07 ? 866 GLN A N 1 ATOM 6899 C CA . GLN A 1 866 ? 30.078 74.042 -14.542 1.00 12.45 ? 866 GLN A CA 1 ATOM 6900 C C . GLN A 1 866 ? 30.464 74.743 -13.238 1.00 12.25 ? 866 GLN A C 1 ATOM 6901 O O . GLN A 1 866 ? 31.644 74.762 -12.871 1.00 13.78 ? 866 GLN A O 1 ATOM 6902 C CB . GLN A 1 866 ? 29.861 75.076 -15.647 1.00 13.27 ? 866 GLN A CB 1 ATOM 6903 C CG . GLN A 1 866 ? 29.559 74.469 -16.983 1.00 14.38 ? 866 GLN A CG 1 ATOM 6904 C CD . GLN A 1 866 ? 30.603 73.480 -17.403 1.00 13.99 ? 866 GLN A CD 1 ATOM 6905 O OE1 . GLN A 1 866 ? 31.734 73.845 -17.772 1.00 14.47 ? 866 GLN A OE1 1 ATOM 6906 N NE2 . GLN A 1 866 ? 30.240 72.210 -17.367 1.00 13.68 ? 866 GLN A NE2 1 ATOM 6907 N N . ASP A 1 867 ? 29.483 75.332 -12.533 1.00 12.74 ? 867 ASP A N 1 ATOM 6908 C CA . ASP A 1 867 ? 29.724 75.965 -11.234 1.00 12.39 ? 867 ASP A CA 1 ATOM 6909 C C . ASP A 1 867 ? 28.388 76.196 -10.581 1.00 14.17 ? 867 ASP A C 1 ATOM 6910 O O . ASP A 1 867 ? 27.320 76.098 -11.237 1.00 13.11 ? 867 ASP A O 1 ATOM 6911 C CB . ASP A 1 867 ? 30.495 77.301 -11.356 1.00 14.05 ? 867 ASP A CB 1 ATOM 6912 C CG . ASP A 1 867 ? 31.244 77.680 -10.066 1.00 13.94 ? 867 ASP A CG 1 ATOM 6913 O OD1 . ASP A 1 867 ? 31.113 77.019 -9.023 1.00 14.43 ? 867 ASP A OD1 1 ATOM 6914 O OD2 . ASP A 1 867 ? 31.984 78.681 -10.110 1.00 14.99 ? 867 ASP A OD2 1 ATOM 6915 N N . ARG A 1 868 ? 28.443 76.471 -9.297 1.00 12.95 ? 868 ARG A N 1 ATOM 6916 C CA . ARG A 1 868 ? 27.236 76.693 -8.512 1.00 13.96 ? 868 ARG A CA 1 ATOM 6917 C C . ARG A 1 868 ? 27.553 77.707 -7.420 1.00 14.07 ? 868 ARG A C 1 ATOM 6918 O O . ARG A 1 868 ? 28.608 77.644 -6.764 1.00 14.78 ? 868 ARG A O 1 ATOM 6919 C CB . ARG A 1 868 ? 26.736 75.345 -7.949 1.00 14.63 ? 868 ARG A CB 1 ATOM 6920 C CG . ARG A 1 868 ? 27.770 74.584 -7.077 1.00 16.63 ? 868 ARG A CG 1 ATOM 6921 C CD . ARG A 1 868 ? 27.477 73.074 -7.086 1.00 13.73 ? 868 ARG A CD 1 ATOM 6922 N NE . ARG A 1 868 ? 26.107 72.791 -6.659 1.00 13.75 ? 868 ARG A NE 1 ATOM 6923 C CZ . ARG A 1 868 ? 25.754 72.509 -5.421 1.00 13.79 ? 868 ARG A CZ 1 ATOM 6924 N NH1 . ARG A 1 868 ? 26.657 72.421 -4.425 1.00 12.86 ? 868 ARG A NH1 1 ATOM 6925 N NH2 . ARG A 1 868 ? 24.450 72.334 -5.171 1.00 14.87 ? 868 ARG A NH2 1 ATOM 6926 N N . ARG A 1 869 ? 26.637 78.667 -7.239 1.00 14.83 ? 869 ARG A N 1 ATOM 6927 C CA . ARG A 1 869 ? 26.812 79.741 -6.245 1.00 14.12 ? 869 ARG A CA 1 ATOM 6928 C C . ARG A 1 869 ? 25.527 79.721 -5.455 1.00 16.60 ? 869 ARG A C 1 ATOM 6929 O O . ARG A 1 869 ? 24.459 79.912 -6.009 1.00 16.63 ? 869 ARG A O 1 ATOM 6930 C CB . ARG A 1 869 ? 27.023 81.085 -6.971 1.00 14.74 ? 869 ARG A CB 1 ATOM 6931 C CG . ARG A 1 869 ? 27.245 82.211 -6.012 1.00 15.40 ? 869 ARG A CG 1 ATOM 6932 C CD . ARG A 1 869 ? 27.526 83.511 -6.757 1.00 19.77 ? 869 ARG A CD 1 ATOM 6933 N NE . ARG A 1 869 ? 27.712 84.659 -5.849 1.00 22.83 ? 869 ARG A NE 1 ATOM 6934 C CZ . ARG A 1 869 ? 28.866 84.993 -5.293 1.00 21.33 ? 869 ARG A CZ 1 ATOM 6935 N NH1 . ARG A 1 869 ? 29.964 84.288 -5.535 1.00 20.03 ? 869 ARG A NH1 1 ATOM 6936 N NH2 . ARG A 1 869 ? 28.914 86.061 -4.485 1.00 24.85 ? 869 ARG A NH2 1 ATOM 6937 N N . LEU A 1 870 ? 25.671 79.464 -4.169 1.00 16.35 ? 870 LEU A N 1 ATOM 6938 C CA . LEU A 1 870 ? 24.531 79.229 -3.260 1.00 17.61 ? 870 LEU A CA 1 ATOM 6939 C C . LEU A 1 870 ? 24.602 80.046 -2.001 1.00 18.06 ? 870 LEU A C 1 ATOM 6940 O O . LEU A 1 870 ? 25.577 80.002 -1.266 1.00 17.90 ? 870 LEU A O 1 ATOM 6941 C CB . LEU A 1 870 ? 24.502 77.736 -2.906 1.00 18.63 ? 870 LEU A CB 1 ATOM 6942 C CG . LEU A 1 870 ? 24.556 76.864 -4.161 1.00 21.89 ? 870 LEU A CG 1 ATOM 6943 C CD1 . LEU A 1 870 ? 25.102 75.538 -3.819 1.00 22.51 ? 870 LEU A CD1 1 ATOM 6944 C CD2 . LEU A 1 870 ? 23.217 76.805 -4.844 1.00 18.40 ? 870 LEU A CD2 1 ATOM 6945 N N . ALA A 1 871 ? 23.517 80.762 -1.732 1.00 18.64 ? 871 ALA A N 1 ATOM 6946 C CA . ALA A 1 871 ? 23.501 81.638 -0.588 1.00 20.76 ? 871 ALA A CA 1 ATOM 6947 C C . ALA A 1 871 ? 23.294 80.962 0.763 1.00 24.19 ? 871 ALA A C 1 ATOM 6948 O O . ALA A 1 871 ? 23.766 81.437 1.798 1.00 25.31 ? 871 ALA A O 1 ATOM 6949 C CB . ALA A 1 871 ? 22.406 82.714 -0.805 1.00 22.60 ? 871 ALA A CB 1 ATOM 6950 N N . SER A 1 872 ? 22.645 79.815 0.748 1.00 22.79 ? 872 SER A N 1 ATOM 6951 C CA . SER A 1 872 ? 22.329 79.175 2.012 1.00 24.49 ? 872 SER A CA 1 ATOM 6952 C C . SER A 1 872 ? 23.166 77.980 2.377 1.00 21.81 ? 872 SER A C 1 ATOM 6953 O O . SER A 1 872 ? 23.777 77.334 1.510 1.00 20.85 ? 872 SER A O 1 ATOM 6954 C CB . SER A 1 872 ? 20.858 78.738 2.010 1.00 28.59 ? 872 SER A CB 1 ATOM 6955 O OG . SER A 1 872 ? 19.999 79.805 1.634 1.00 32.86 ? 872 SER A OG 1 ATOM 6956 N N . ASP A 1 873 ? 23.211 77.723 3.677 1.00 22.17 ? 873 ASP A N 1 ATOM 6957 C CA . ASP A 1 873 ? 23.876 76.543 4.244 1.00 21.01 ? 873 ASP A CA 1 ATOM 6958 C C . ASP A 1 873 ? 22.852 75.407 4.076 1.00 22.45 ? 873 ASP A C 1 ATOM 6959 O O . ASP A 1 873 ? 21.639 75.654 4.092 1.00 22.43 ? 873 ASP A O 1 ATOM 6960 C CB . ASP A 1 873 ? 24.181 76.750 5.723 1.00 21.04 ? 873 ASP A CB 1 ATOM 6961 C CG . ASP A 1 873 ? 24.676 75.483 6.378 1.00 20.99 ? 873 ASP A CG 1 ATOM 6962 O OD1 . ASP A 1 873 ? 25.769 75.005 5.973 1.00 20.79 ? 873 ASP A OD1 1 ATOM 6963 O OD2 . ASP A 1 873 ? 23.967 74.951 7.255 1.00 23.24 ? 873 ASP A OD2 1 ATOM 6964 N N . ASP A 1 874 ? 23.345 74.179 3.865 1.00 19.24 ? 874 ASP A N 1 ATOM 6965 C CA . ASP A 1 874 ? 22.448 73.041 3.669 1.00 17.39 ? 874 ASP A CA 1 ATOM 6966 C C . ASP A 1 874 ? 22.383 72.072 4.858 1.00 18.01 ? 874 ASP A C 1 ATOM 6967 O O . ASP A 1 874 ? 22.200 70.861 4.711 1.00 20.70 ? 874 ASP A O 1 ATOM 6968 C CB . ASP A 1 874 ? 22.782 72.310 2.367 1.00 18.77 ? 874 ASP A CB 1 ATOM 6969 C CG . ASP A 1 874 ? 24.249 71.939 2.257 1.00 16.50 ? 874 ASP A CG 1 ATOM 6970 O OD1 . ASP A 1 874 ? 25.079 72.217 3.176 1.00 19.27 ? 874 ASP A OD1 1 ATOM 6971 O OD2 . ASP A 1 874 ? 24.561 71.356 1.201 1.00 16.72 ? 874 ASP A OD2 1 ATOM 6972 N N . GLU A 1 875 ? 22.638 72.619 6.036 1.00 19.69 ? 875 GLU A N 1 ATOM 6973 C CA . GLU A 1 875 ? 22.452 71.861 7.272 1.00 20.31 ? 875 GLU A CA 1 ATOM 6974 C C . GLU A 1 875 ? 23.244 70.591 7.481 1.00 21.17 ? 875 GLU A C 1 ATOM 6975 O O . GLU A 1 875 ? 22.797 69.676 8.179 1.00 19.83 ? 875 GLU A O 1 ATOM 6976 C CB . GLU A 1 875 ? 20.950 71.564 7.451 1.00 24.39 ? 875 GLU A CB 1 ATOM 6977 C CG . GLU A 1 875 ? 20.063 72.829 7.367 1.00 31.56 ? 875 GLU A CG 1 ATOM 6978 C CD . GLU A 1 875 ? 18.688 72.657 8.016 1.00 37.13 ? 875 GLU A CD 1 ATOM 6979 O OE1 . GLU A 1 875 ? 18.627 72.320 9.216 1.00 42.54 ? 875 GLU A OE1 1 ATOM 6980 O OE2 . GLU A 1 875 ? 17.664 72.859 7.328 1.00 40.36 ? 875 GLU A OE2 1 ATOM 6981 N N . ARG A 1 876 ? 24.431 70.534 6.895 1.00 18.18 ? 876 ARG A N 1 ATOM 6982 C CA . ARG A 1 876 ? 25.303 69.363 7.098 1.00 17.83 ? 876 ARG A CA 1 ATOM 6983 C C . ARG A 1 876 ? 26.557 69.746 7.897 1.00 17.85 ? 876 ARG A C 1 ATOM 6984 O O . ARG A 1 876 ? 27.555 69.017 7.916 1.00 18.77 ? 876 ARG A O 1 ATOM 6985 C CB . ARG A 1 876 ? 25.656 68.734 5.745 1.00 17.90 ? 876 ARG A CB 1 ATOM 6986 C CG . ARG A 1 876 ? 24.410 68.190 5.004 1.00 15.94 ? 876 ARG A CG 1 ATOM 6987 C CD . ARG A 1 876 ? 23.662 67.201 5.912 1.00 16.29 ? 876 ARG A CD 1 ATOM 6988 N NE . ARG A 1 876 ? 22.553 66.506 5.248 1.00 15.99 ? 876 ARG A NE 1 ATOM 6989 C CZ . ARG A 1 876 ? 21.358 67.042 4.972 1.00 19.53 ? 876 ARG A CZ 1 ATOM 6990 N NH1 . ARG A 1 876 ? 21.094 68.329 5.259 1.00 17.81 ? 876 ARG A NH1 1 ATOM 6991 N NH2 . ARG A 1 876 ? 20.392 66.268 4.488 1.00 16.71 ? 876 ARG A NH2 1 ATOM 6992 N N . GLY A 1 877 ? 26.516 70.926 8.513 1.00 19.11 ? 877 GLY A N 1 ATOM 6993 C CA . GLY A 1 877 ? 27.602 71.377 9.366 1.00 18.07 ? 877 GLY A CA 1 ATOM 6994 C C . GLY A 1 877 ? 28.589 72.379 8.841 1.00 16.27 ? 877 GLY A C 1 ATOM 6995 O O . GLY A 1 877 ? 29.396 72.891 9.634 1.00 18.88 ? 877 GLY A O 1 ATOM 6996 N N . LEU A 1 878 ? 28.547 72.670 7.542 1.00 16.83 ? 878 LEU A N 1 ATOM 6997 C CA . LEU A 1 878 ? 29.506 73.625 6.987 1.00 18.56 ? 878 LEU A CA 1 ATOM 6998 C C . LEU A 1 878 ? 29.255 75.050 7.534 1.00 19.96 ? 878 LEU A C 1 ATOM 6999 O O . LEU A 1 878 ? 30.209 75.805 7.796 1.00 19.64 ? 878 LEU A O 1 ATOM 7000 C CB . LEU A 1 878 ? 29.448 73.606 5.440 1.00 18.35 ? 878 LEU A CB 1 ATOM 7001 C CG . LEU A 1 878 ? 30.197 74.697 4.649 1.00 19.67 ? 878 LEU A CG 1 ATOM 7002 C CD1 . LEU A 1 878 ? 31.681 74.692 5.041 1.00 20.13 ? 878 LEU A CD1 1 ATOM 7003 C CD2 . LEU A 1 878 ? 30.033 74.467 3.150 1.00 18.56 ? 878 LEU A CD2 1 ATOM 7004 N N . GLY A 1 879 ? 27.985 75.403 7.712 1.00 19.42 ? 879 GLY A N 1 ATOM 7005 C CA . GLY A 1 879 ? 27.671 76.724 8.244 1.00 20.93 ? 879 GLY A CA 1 ATOM 7006 C C . GLY A 1 879 ? 27.847 77.928 7.326 1.00 22.61 ? 879 GLY A C 1 ATOM 7007 O O . GLY A 1 879 ? 28.012 79.053 7.804 1.00 23.94 ? 879 GLY A O 1 ATOM 7008 N N . GLN A 1 880 ? 27.857 77.717 6.018 1.00 20.57 ? 880 GLN A N 1 ATOM 7009 C CA . GLN A 1 880 ? 27.949 78.842 5.088 1.00 19.59 ? 880 GLN A CA 1 ATOM 7010 C C . GLN A 1 880 ? 27.450 78.321 3.752 1.00 21.10 ? 880 GLN A C 1 ATOM 7011 O O . GLN A 1 880 ? 27.336 77.100 3.576 1.00 21.93 ? 880 GLN A O 1 ATOM 7012 C CB . GLN A 1 880 ? 29.411 79.358 4.960 1.00 19.78 ? 880 GLN A CB 1 ATOM 7013 C CG . GLN A 1 880 ? 30.465 78.328 4.521 1.00 21.53 ? 880 GLN A CG 1 ATOM 7014 C CD . GLN A 1 880 ? 31.701 78.979 3.900 1.00 17.41 ? 880 GLN A CD 1 ATOM 7015 O OE1 . GLN A 1 880 ? 31.741 79.223 2.699 1.00 23.13 ? 880 GLN A OE1 1 ATOM 7016 N NE2 . GLN A 1 880 ? 32.677 79.264 4.697 1.00 16.24 ? 880 GLN A NE2 1 ATOM 7017 N N . GLY A 1 881 ? 27.119 79.237 2.851 1.00 20.79 ? 881 GLY A N 1 ATOM 7018 C CA . GLY A 1 881 ? 26.735 78.843 1.497 1.00 22.24 ? 881 GLY A CA 1 ATOM 7019 C C . GLY A 1 881 ? 28.043 78.752 0.707 1.00 20.26 ? 881 GLY A C 1 ATOM 7020 O O . GLY A 1 881 ? 29.133 78.605 1.257 1.00 22.10 ? 881 GLY A O 1 ATOM 7021 N N . VAL A 1 882 ? 27.917 78.803 -0.607 1.00 18.76 ? 882 VAL A N 1 ATOM 7022 C CA . VAL A 1 882 ? 29.071 78.764 -1.494 1.00 16.94 ? 882 VAL A CA 1 ATOM 7023 C C . VAL A 1 882 ? 29.006 80.069 -2.273 1.00 16.71 ? 882 VAL A C 1 ATOM 7024 O O . VAL A 1 882 ? 28.272 80.204 -3.269 1.00 15.96 ? 882 VAL A O 1 ATOM 7025 C CB . VAL A 1 882 ? 29.010 77.538 -2.448 1.00 17.60 ? 882 VAL A CB 1 ATOM 7026 C CG1 . VAL A 1 882 ? 30.163 77.584 -3.433 1.00 16.80 ? 882 VAL A CG1 1 ATOM 7027 C CG2 . VAL A 1 882 ? 29.052 76.230 -1.606 1.00 18.38 ? 882 VAL A CG2 1 ATOM 7028 N N . LEU A 1 883 ? 29.770 81.047 -1.785 1.00 18.23 ? 883 LEU A N 1 ATOM 7029 C CA . LEU A 1 883 ? 29.761 82.392 -2.405 1.00 19.15 ? 883 LEU A CA 1 ATOM 7030 C C . LEU A 1 883 ? 31.173 82.879 -2.695 1.00 20.01 ? 883 LEU A C 1 ATOM 7031 O O . LEU A 1 883 ? 31.391 84.080 -2.846 1.00 23.68 ? 883 LEU A O 1 ATOM 7032 C CB . LEU A 1 883 ? 29.061 83.372 -1.440 1.00 19.62 ? 883 LEU A CB 1 ATOM 7033 C CG . LEU A 1 883 ? 27.591 83.058 -1.122 1.00 18.78 ? 883 LEU A CG 1 ATOM 7034 C CD1 . LEU A 1 883 ? 27.021 84.001 -0.007 1.00 20.51 ? 883 LEU A CD1 1 ATOM 7035 C CD2 . LEU A 1 883 ? 26.758 83.240 -2.385 1.00 20.72 ? 883 LEU A CD2 1 ATOM 7036 N N . ASP A 1 884 ? 32.127 81.962 -2.761 1.00 16.92 ? 884 ASP A N 1 ATOM 7037 C CA . ASP A 1 884 ? 33.531 82.270 -2.987 1.00 16.55 ? 884 ASP A CA 1 ATOM 7038 C C . ASP A 1 884 ? 34.026 81.818 -4.332 1.00 16.93 ? 884 ASP A C 1 ATOM 7039 O O . ASP A 1 884 ? 35.213 81.533 -4.490 1.00 17.20 ? 884 ASP A O 1 ATOM 7040 C CB . ASP A 1 884 ? 34.428 81.663 -1.891 1.00 17.75 ? 884 ASP A CB 1 ATOM 7041 C CG . ASP A 1 884 ? 34.195 80.148 -1.661 1.00 19.04 ? 884 ASP A CG 1 ATOM 7042 O OD1 . ASP A 1 884 ? 33.394 79.517 -2.397 1.00 17.85 ? 884 ASP A OD1 1 ATOM 7043 O OD2 . ASP A 1 884 ? 34.851 79.640 -0.712 1.00 21.48 ? 884 ASP A OD2 1 ATOM 7044 N N . ASN A 1 885 ? 33.114 81.761 -5.296 1.00 14.57 ? 885 ASN A N 1 ATOM 7045 C CA . ASN A 1 885 ? 33.456 81.342 -6.634 1.00 15.95 ? 885 ASN A CA 1 ATOM 7046 C C . ASN A 1 885 ? 34.518 82.218 -7.247 1.00 16.35 ? 885 ASN A C 1 ATOM 7047 O O . ASN A 1 885 ? 34.635 83.410 -6.917 1.00 17.22 ? 885 ASN A O 1 ATOM 7048 C CB . ASN A 1 885 ? 32.225 81.440 -7.540 1.00 15.29 ? 885 ASN A CB 1 ATOM 7049 C CG . ASN A 1 885 ? 31.014 80.727 -6.964 1.00 16.82 ? 885 ASN A CG 1 ATOM 7050 O OD1 . ASN A 1 885 ? 30.667 79.612 -7.406 1.00 18.32 ? 885 ASN A OD1 1 ATOM 7051 N ND2 . ASN A 1 885 ? 30.354 81.339 -6.009 1.00 15.15 ? 885 ASN A ND2 1 ATOM 7052 N N . LYS A 1 886 ? 35.277 81.629 -8.158 1.00 15.75 ? 886 LYS A N 1 ATOM 7053 C CA . LYS A 1 886 ? 36.292 82.361 -8.886 1.00 18.00 ? 886 LYS A CA 1 ATOM 7054 C C . LYS A 1 886 ? 36.373 81.783 -10.282 1.00 16.62 ? 886 LYS A C 1 ATOM 7055 O O . LYS A 1 886 ? 35.986 80.646 -10.532 1.00 16.33 ? 886 LYS A O 1 ATOM 7056 C CB . LYS A 1 886 ? 37.632 82.265 -8.127 1.00 21.68 ? 886 LYS A CB 1 ATOM 7057 C CG . LYS A 1 886 ? 38.110 80.831 -7.896 1.00 21.22 ? 886 LYS A CG 1 ATOM 7058 C CD . LYS A 1 886 ? 39.231 80.693 -6.816 1.00 26.18 ? 886 LYS A CD 1 ATOM 7059 C CE . LYS A 1 886 ? 40.537 81.231 -7.340 1.00 27.11 ? 886 LYS A CE 1 ATOM 7060 N NZ . LYS A 1 886 ? 41.622 81.312 -6.297 1.00 28.34 ? 886 LYS A NZ 1 ATOM 7061 N N . PRO A 1 887 ? 36.864 82.555 -11.234 1.00 14.14 ? 887 PRO A N 1 ATOM 7062 C CA . PRO A 1 887 ? 36.975 82.069 -12.609 1.00 14.25 ? 887 PRO A CA 1 ATOM 7063 C C . PRO A 1 887 ? 37.755 80.784 -12.701 1.00 14.68 ? 887 PRO A C 1 ATOM 7064 O O . PRO A 1 887 ? 38.806 80.622 -12.090 1.00 15.93 ? 887 PRO A O 1 ATOM 7065 C CB . PRO A 1 887 ? 37.685 83.218 -13.341 1.00 16.02 ? 887 PRO A CB 1 ATOM 7066 C CG . PRO A 1 887 ? 37.214 84.451 -12.552 1.00 15.73 ? 887 PRO A CG 1 ATOM 7067 C CD . PRO A 1 887 ? 37.193 83.989 -11.122 1.00 14.77 ? 887 PRO A CD 1 ATOM 7068 N N . VAL A 1 888 ? 37.240 79.852 -13.485 1.00 13.20 ? 888 VAL A N 1 ATOM 7069 C CA . VAL A 1 888 ? 37.905 78.573 -13.693 1.00 12.93 ? 888 VAL A CA 1 ATOM 7070 C C . VAL A 1 888 ? 37.839 78.191 -15.155 1.00 12.00 ? 888 VAL A C 1 ATOM 7071 O O . VAL A 1 888 ? 36.810 78.474 -15.822 1.00 12.89 ? 888 VAL A O 1 ATOM 7072 C CB . VAL A 1 888 ? 37.238 77.464 -12.769 1.00 14.79 ? 888 VAL A CB 1 ATOM 7073 C CG1 . VAL A 1 888 ? 35.708 77.370 -13.055 1.00 15.86 ? 888 VAL A CG1 1 ATOM 7074 C CG2 . VAL A 1 888 ? 37.905 76.122 -12.987 1.00 14.11 ? 888 VAL A CG2 1 ATOM 7075 N N . LEU A 1 889 ? 38.920 77.618 -15.682 1.00 11.71 ? 889 LEU A N 1 ATOM 7076 C CA . LEU A 1 889 ? 38.940 77.135 -17.045 1.00 12.50 ? 889 LEU A CA 1 ATOM 7077 C C . LEU A 1 889 ? 38.729 75.611 -17.071 1.00 12.10 ? 889 LEU A C 1 ATOM 7078 O O . LEU A 1 889 ? 39.622 74.818 -16.749 1.00 13.77 ? 889 LEU A O 1 ATOM 7079 C CB . LEU A 1 889 ? 40.263 77.497 -17.732 1.00 12.94 ? 889 LEU A CB 1 ATOM 7080 C CG . LEU A 1 889 ? 40.349 77.061 -19.209 1.00 15.38 ? 889 LEU A CG 1 ATOM 7081 C CD1 . LEU A 1 889 ? 39.374 77.963 -20.020 1.00 17.54 ? 889 LEU A CD1 1 ATOM 7082 C CD2 . LEU A 1 889 ? 41.776 77.167 -19.738 1.00 18.23 ? 889 LEU A CD2 1 ATOM 7083 N N . HIS A 1 890 ? 37.512 75.214 -17.415 1.00 11.97 ? 890 HIS A N 1 ATOM 7084 C CA . HIS A 1 890 ? 37.198 73.785 -17.546 1.00 12.21 ? 890 HIS A CA 1 ATOM 7085 C C . HIS A 1 890 ? 37.583 73.300 -18.928 1.00 13.90 ? 890 HIS A C 1 ATOM 7086 O O . HIS A 1 890 ? 37.377 74.025 -19.912 1.00 14.05 ? 890 HIS A O 1 ATOM 7087 C CB . HIS A 1 890 ? 35.700 73.531 -17.331 1.00 11.98 ? 890 HIS A CB 1 ATOM 7088 C CG . HIS A 1 890 ? 35.250 73.722 -15.925 1.00 11.69 ? 890 HIS A CG 1 ATOM 7089 N ND1 . HIS A 1 890 ? 36.050 73.337 -14.863 1.00 13.96 ? 890 HIS A ND1 1 ATOM 7090 C CD2 . HIS A 1 890 ? 34.084 74.158 -15.395 1.00 13.59 ? 890 HIS A CD2 1 ATOM 7091 C CE1 . HIS A 1 890 ? 35.379 73.514 -13.736 1.00 14.99 ? 890 HIS A CE1 1 ATOM 7092 N NE2 . HIS A 1 890 ? 34.183 74.013 -14.032 1.00 13.03 ? 890 HIS A NE2 1 ATOM 7093 N N . ILE A 1 891 ? 38.110 72.089 -19.025 1.00 11.25 ? 891 ILE A N 1 ATOM 7094 C CA . ILE A 1 891 ? 38.500 71.552 -20.302 1.00 11.54 ? 891 ILE A CA 1 ATOM 7095 C C . ILE A 1 891 ? 37.841 70.217 -20.550 1.00 11.30 ? 891 ILE A C 1 ATOM 7096 O O . ILE A 1 891 ? 37.569 69.433 -19.628 1.00 12.09 ? 891 ILE A O 1 ATOM 7097 C CB . ILE A 1 891 ? 40.021 71.468 -20.447 1.00 11.78 ? 891 ILE A CB 1 ATOM 7098 C CG1 . ILE A 1 891 ? 40.638 70.506 -19.437 1.00 14.56 ? 891 ILE A CG1 1 ATOM 7099 C CG2 . ILE A 1 891 ? 40.630 72.887 -20.200 1.00 13.79 ? 891 ILE A CG2 1 ATOM 7100 C CD1 . ILE A 1 891 ? 42.154 70.315 -19.696 1.00 14.86 ? 891 ILE A CD1 1 ATOM 7101 N N . TYR A 1 892 ? 37.582 69.941 -21.825 1.00 10.84 ? 892 TYR A N 1 ATOM 7102 C CA . TYR A 1 892 ? 36.915 68.703 -22.241 1.00 12.03 ? 892 TYR A CA 1 ATOM 7103 C C . TYR A 1 892 ? 37.331 68.254 -23.614 1.00 11.74 ? 892 TYR A C 1 ATOM 7104 O O . TYR A 1 892 ? 37.919 69.035 -24.368 1.00 11.94 ? 892 TYR A O 1 ATOM 7105 C CB . TYR A 1 892 ? 35.396 68.911 -22.383 1.00 12.55 ? 892 TYR A CB 1 ATOM 7106 C CG . TYR A 1 892 ? 34.724 69.583 -21.202 1.00 10.12 ? 892 TYR A CG 1 ATOM 7107 C CD1 . TYR A 1 892 ? 34.698 70.972 -21.059 1.00 11.03 ? 892 TYR A CD1 1 ATOM 7108 C CD2 . TYR A 1 892 ? 34.122 68.808 -20.197 1.00 12.18 ? 892 TYR A CD2 1 ATOM 7109 C CE1 . TYR A 1 892 ? 34.110 71.577 -19.957 1.00 10.28 ? 892 TYR A CE1 1 ATOM 7110 C CE2 . TYR A 1 892 ? 33.526 69.395 -19.111 1.00 11.34 ? 892 TYR A CE2 1 ATOM 7111 C CZ . TYR A 1 892 ? 33.528 70.783 -18.990 1.00 11.58 ? 892 TYR A CZ 1 ATOM 7112 O OH . TYR A 1 892 ? 32.940 71.358 -17.901 1.00 12.74 ? 892 TYR A OH 1 ATOM 7113 N N . ARG A 1 893 ? 37.023 66.988 -23.949 1.00 10.61 ? 893 ARG A N 1 ATOM 7114 C CA . ARG A 1 893 ? 37.150 66.517 -25.351 1.00 11.32 ? 893 ARG A CA 1 ATOM 7115 C C . ARG A 1 893 ? 35.792 65.914 -25.654 1.00 12.13 ? 893 ARG A C 1 ATOM 7116 O O . ARG A 1 893 ? 35.170 65.285 -24.804 1.00 13.66 ? 893 ARG A O 1 ATOM 7117 C CB . ARG A 1 893 ? 38.249 65.495 -25.567 1.00 11.85 ? 893 ARG A CB 1 ATOM 7118 C CG . ARG A 1 893 ? 39.635 66.038 -25.279 1.00 13.48 ? 893 ARG A CG 1 ATOM 7119 C CD . ARG A 1 893 ? 40.094 67.116 -26.323 1.00 12.59 ? 893 ARG A CD 1 ATOM 7120 N NE . ARG A 1 893 ? 40.249 66.583 -27.675 1.00 13.00 ? 893 ARG A NE 1 ATOM 7121 C CZ . ARG A 1 893 ? 41.321 65.935 -28.112 1.00 13.85 ? 893 ARG A CZ 1 ATOM 7122 N NH1 . ARG A 1 893 ? 42.345 65.729 -27.277 1.00 15.43 ? 893 ARG A NH1 1 ATOM 7123 N NH2 . ARG A 1 893 ? 41.412 65.507 -29.372 1.00 17.31 ? 893 ARG A NH2 1 ATOM 7124 N N . LEU A 1 894 ? 35.327 66.107 -26.893 1.00 13.20 ? 894 LEU A N 1 ATOM 7125 C CA . LEU A 1 894 ? 34.015 65.609 -27.335 1.00 14.55 ? 894 LEU A CA 1 ATOM 7126 C C . LEU A 1 894 ? 34.251 64.635 -28.487 1.00 13.66 ? 894 LEU A C 1 ATOM 7127 O O . LEU A 1 894 ? 34.786 65.003 -29.529 1.00 15.55 ? 894 LEU A O 1 ATOM 7128 C CB . LEU A 1 894 ? 33.186 66.796 -27.785 1.00 15.21 ? 894 LEU A CB 1 ATOM 7129 C CG . LEU A 1 894 ? 31.747 66.414 -28.132 1.00 16.53 ? 894 LEU A CG 1 ATOM 7130 C CD1 . LEU A 1 894 ? 30.993 65.918 -26.883 1.00 19.62 ? 894 LEU A CD1 1 ATOM 7131 C CD2 . LEU A 1 894 ? 31.029 67.635 -28.748 1.00 19.53 ? 894 LEU A CD2 1 ATOM 7132 N N . VAL A 1 895 ? 33.894 63.374 -28.258 1.00 13.15 ? 895 VAL A N 1 ATOM 7133 C CA . VAL A 1 895 ? 34.114 62.328 -29.236 1.00 15.07 ? 895 VAL A CA 1 ATOM 7134 C C . VAL A 1 895 ? 32.823 61.683 -29.716 1.00 14.94 ? 895 VAL A C 1 ATOM 7135 O O . VAL A 1 895 ? 32.139 60.963 -28.971 1.00 14.55 ? 895 VAL A O 1 ATOM 7136 C CB . VAL A 1 895 ? 34.993 61.228 -28.624 1.00 14.38 ? 895 VAL A CB 1 ATOM 7137 C CG1 . VAL A 1 895 ? 35.407 60.251 -29.725 1.00 17.97 ? 895 VAL A CG1 1 ATOM 7138 C CG2 . VAL A 1 895 ? 36.215 61.854 -27.917 1.00 17.29 ? 895 VAL A CG2 1 ATOM 7139 N N . LEU A 1 896 ? 32.451 61.971 -30.966 1.00 15.83 ? 896 LEU A N 1 ATOM 7140 C CA . LEU A 1 896 ? 31.260 61.367 -31.587 1.00 15.53 ? 896 LEU A CA 1 ATOM 7141 C C . LEU A 1 896 ? 31.842 60.234 -32.437 1.00 16.79 ? 896 LEU A C 1 ATOM 7142 O O . LEU A 1 896 ? 32.792 60.443 -33.188 1.00 17.93 ? 896 LEU A O 1 ATOM 7143 C CB . LEU A 1 896 ? 30.570 62.398 -32.493 1.00 14.97 ? 896 LEU A CB 1 ATOM 7144 C CG . LEU A 1 896 ? 29.371 61.774 -33.248 1.00 17.87 ? 896 LEU A CG 1 ATOM 7145 C CD1 . LEU A 1 896 ? 28.207 61.594 -32.304 1.00 20.19 ? 896 LEU A CD1 1 ATOM 7146 C CD2 . LEU A 1 896 ? 28.928 62.729 -34.364 1.00 18.31 ? 896 LEU A CD2 1 ATOM 7147 N N . GLU A 1 897 ? 31.308 59.018 -32.269 1.00 15.59 ? 897 GLU A N 1 ATOM 7148 C CA . GLU A 1 897 ? 31.835 57.881 -33.001 1.00 17.55 ? 897 GLU A CA 1 ATOM 7149 C C . GLU A 1 897 ? 30.725 56.910 -33.413 1.00 16.80 ? 897 GLU A C 1 ATOM 7150 O O . GLU A 1 897 ? 29.682 56.823 -32.762 1.00 17.14 ? 897 GLU A O 1 ATOM 7151 C CB . GLU A 1 897 ? 32.787 57.068 -32.098 1.00 20.10 ? 897 GLU A CB 1 ATOM 7152 C CG . GLU A 1 897 ? 33.835 57.840 -31.360 1.00 24.11 ? 897 GLU A CG 1 ATOM 7153 C CD . GLU A 1 897 ? 34.470 56.960 -30.235 1.00 19.91 ? 897 GLU A CD 1 ATOM 7154 O OE1 . GLU A 1 897 ? 33.827 56.731 -29.171 1.00 23.98 ? 897 GLU A OE1 1 ATOM 7155 O OE2 . GLU A 1 897 ? 35.600 56.540 -30.499 1.00 26.41 ? 897 GLU A OE2 1 ATOM 7156 N N . LYS A 1 898 ? 31.004 56.140 -34.460 1.00 18.59 ? 898 LYS A N 1 ATOM 7157 C CA . LYS A 1 898 ? 30.100 55.054 -34.870 1.00 20.26 ? 898 LYS A CA 1 ATOM 7158 C C . LYS A 1 898 ? 30.560 53.831 -34.073 1.00 20.29 ? 898 LYS A C 1 ATOM 7159 O O . LYS A 1 898 ? 31.753 53.511 -34.026 1.00 23.98 ? 898 LYS A O 1 ATOM 7160 C CB . LYS A 1 898 ? 30.256 54.747 -36.364 1.00 20.92 ? 898 LYS A CB 1 ATOM 7161 C CG . LYS A 1 898 ? 29.906 55.876 -37.282 1.00 26.97 ? 898 LYS A CG 1 ATOM 7162 C CD . LYS A 1 898 ? 28.582 56.600 -36.930 1.00 32.63 ? 898 LYS A CD 1 ATOM 7163 C CE . LYS A 1 898 ? 27.344 55.667 -36.720 1.00 33.73 ? 898 LYS A CE 1 ATOM 7164 N NZ . LYS A 1 898 ? 27.102 54.634 -37.780 1.00 37.00 ? 898 LYS A NZ 1 ATOM 7165 N N . VAL A 1 899 ? 29.626 53.142 -33.443 1.00 19.67 ? 899 VAL A N 1 ATOM 7166 C CA . VAL A 1 899 ? 29.984 51.988 -32.633 1.00 20.43 ? 899 VAL A CA 1 ATOM 7167 C C . VAL A 1 899 ? 29.261 50.697 -33.020 1.00 21.09 ? 899 VAL A C 1 ATOM 7168 O O . VAL A 1 899 ? 29.350 49.708 -32.319 1.00 19.92 ? 899 VAL A O 1 ATOM 7169 C CB . VAL A 1 899 ? 29.728 52.302 -31.143 1.00 21.01 ? 899 VAL A CB 1 ATOM 7170 C CG1 . VAL A 1 899 ? 30.761 53.376 -30.662 1.00 21.66 ? 899 VAL A CG1 1 ATOM 7171 C CG2 . VAL A 1 899 ? 28.315 52.826 -30.945 1.00 20.95 ? 899 VAL A CG2 1 ATOM 7172 N N . ASN A 1 900 ? 28.558 50.703 -34.149 1.00 19.79 ? 900 ASN A N 1 ATOM 7173 C CA . ASN A 1 900 ? 27.835 49.497 -34.544 1.00 21.10 ? 900 ASN A CA 1 ATOM 7174 C C . ASN A 1 900 ? 28.781 48.328 -34.805 1.00 21.17 ? 900 ASN A C 1 ATOM 7175 O O . ASN A 1 900 ? 28.349 47.172 -34.758 1.00 23.77 ? 900 ASN A O 1 ATOM 7176 C CB . ASN A 1 900 ? 27.005 49.749 -35.815 1.00 24.21 ? 900 ASN A CB 1 ATOM 7177 C CG . ASN A 1 900 ? 27.820 50.331 -36.936 1.00 26.49 ? 900 ASN A CG 1 ATOM 7178 O OD1 . ASN A 1 900 ? 28.406 51.408 -36.814 1.00 30.67 ? 900 ASN A OD1 1 ATOM 7179 N ND2 . ASN A 1 900 ? 27.873 49.610 -38.068 1.00 30.44 ? 900 ASN A ND2 1 ATOM 7180 N N . ASN A 1 901 ? 30.042 48.595 -35.103 1.00 18.85 ? 901 ASN A N 1 ATOM 7181 C CA . ASN A 1 901 ? 30.970 47.494 -35.336 1.00 19.93 ? 901 ASN A CA 1 ATOM 7182 C C . ASN A 1 901 ? 31.776 47.098 -34.101 1.00 19.73 ? 901 ASN A C 1 ATOM 7183 O O . ASN A 1 901 ? 32.538 46.150 -34.140 1.00 20.16 ? 901 ASN A O 1 ATOM 7184 C CB . ASN A 1 901 ? 31.931 47.817 -36.469 1.00 22.51 ? 901 ASN A CB 1 ATOM 7185 C CG . ASN A 1 901 ? 31.240 47.838 -37.788 1.00 26.78 ? 901 ASN A CG 1 ATOM 7186 O OD1 . ASN A 1 901 ? 30.600 46.866 -38.176 1.00 32.28 ? 901 ASN A OD1 1 ATOM 7187 N ND2 . ASN A 1 901 ? 31.351 48.957 -38.493 1.00 33.29 ? 901 ASN A ND2 1 ATOM 7188 N N . CYS A 1 902 ? 31.557 47.776 -32.987 1.00 19.34 ? 902 CYS A N 1 ATOM 7189 C CA . CYS A 1 902 ? 32.327 47.458 -31.784 1.00 19.89 ? 902 CYS A CA 1 ATOM 7190 C C . CYS A 1 902 ? 31.782 46.275 -31.025 1.00 17.46 ? 902 CYS A C 1 ATOM 7191 O O . CYS A 1 902 ? 30.579 46.099 -30.939 1.00 19.98 ? 902 CYS A O 1 ATOM 7192 C CB . CYS A 1 902 ? 32.307 48.624 -30.815 1.00 19.92 ? 902 CYS A CB 1 ATOM 7193 S SG . CYS A 1 902 ? 33.015 50.174 -31.426 1.00 23.29 ? 902 CYS A SG 1 ATOM 7194 N N . VAL A 1 903 ? 32.670 45.468 -30.463 1.00 16.77 ? 903 VAL A N 1 ATOM 7195 C CA . VAL A 1 903 ? 32.259 44.342 -29.634 1.00 18.47 ? 903 VAL A CA 1 ATOM 7196 C C . VAL A 1 903 ? 31.969 44.920 -28.240 1.00 18.80 ? 903 VAL A C 1 ATOM 7197 O O . VAL A 1 903 ? 32.886 45.231 -27.450 1.00 20.32 ? 903 VAL A O 1 ATOM 7198 C CB . VAL A 1 903 ? 33.393 43.291 -29.590 1.00 16.89 ? 903 VAL A CB 1 ATOM 7199 C CG1 . VAL A 1 903 ? 32.982 42.146 -28.654 1.00 19.00 ? 903 VAL A CG1 1 ATOM 7200 C CG2 . VAL A 1 903 ? 33.619 42.696 -30.990 1.00 20.36 ? 903 VAL A CG2 1 ATOM 7201 N N . ARG A 1 904 ? 30.702 45.053 -27.923 1.00 18.58 ? 904 ARG A N 1 ATOM 7202 C CA . ARG A 1 904 ? 30.286 45.631 -26.653 1.00 17.89 ? 904 ARG A CA 1 ATOM 7203 C C . ARG A 1 904 ? 29.724 44.603 -25.700 1.00 18.07 ? 904 ARG A C 1 ATOM 7204 O O . ARG A 1 904 ? 29.333 43.496 -26.098 1.00 18.54 ? 904 ARG A O 1 ATOM 7205 C CB . ARG A 1 904 ? 29.219 46.725 -26.896 1.00 19.26 ? 904 ARG A CB 1 ATOM 7206 C CG . ARG A 1 904 ? 29.833 47.966 -27.577 1.00 19.91 ? 904 ARG A CG 1 ATOM 7207 C CD . ARG A 1 904 ? 28.821 49.054 -27.834 1.00 23.60 ? 904 ARG A CD 1 ATOM 7208 N NE . ARG A 1 904 ? 28.032 48.706 -29.005 1.00 21.83 ? 904 ARG A NE 1 ATOM 7209 C CZ . ARG A 1 904 ? 27.018 49.439 -29.459 1.00 26.01 ? 904 ARG A CZ 1 ATOM 7210 N NH1 . ARG A 1 904 ? 26.661 50.559 -28.845 1.00 25.87 ? 904 ARG A NH1 1 ATOM 7211 N NH2 . ARG A 1 904 ? 26.354 49.032 -30.533 1.00 27.35 ? 904 ARG A NH2 1 ATOM 7212 N N . PRO A 1 905 ? 29.709 44.938 -24.407 1.00 16.42 ? 905 PRO A N 1 ATOM 7213 C CA . PRO A 1 905 ? 29.152 44.005 -23.433 1.00 17.14 ? 905 PRO A CA 1 ATOM 7214 C C . PRO A 1 905 ? 27.679 43.787 -23.750 1.00 17.44 ? 905 PRO A C 1 ATOM 7215 O O . PRO A 1 905 ? 27.037 44.609 -24.404 1.00 18.34 ? 905 PRO A O 1 ATOM 7216 C CB . PRO A 1 905 ? 29.298 44.757 -22.108 1.00 14.59 ? 905 PRO A CB 1 ATOM 7217 C CG . PRO A 1 905 ? 30.476 45.716 -22.342 1.00 15.15 ? 905 PRO A CG 1 ATOM 7218 C CD . PRO A 1 905 ? 30.207 46.181 -23.769 1.00 17.29 ? 905 PRO A CD 1 ATOM 7219 N N . SER A 1 906 ? 27.138 42.677 -23.274 1.00 17.10 ? 906 SER A N 1 ATOM 7220 C CA . SER A 1 906 ? 25.719 42.392 -23.429 1.00 21.82 ? 906 SER A CA 1 ATOM 7221 C C . SER A 1 906 ? 24.899 43.410 -22.638 1.00 21.07 ? 906 SER A C 1 ATOM 7222 O O . SER A 1 906 ? 25.413 44.124 -21.743 1.00 20.29 ? 906 SER A O 1 ATOM 7223 C CB . SER A 1 906 ? 25.392 41.018 -22.865 1.00 24.72 ? 906 SER A CB 1 ATOM 7224 O OG . SER A 1 906 ? 25.016 41.154 -21.508 1.00 31.01 ? 906 SER A OG 1 ATOM 7225 N N . LYS A 1 907 ? 23.616 43.466 -22.944 1.00 22.19 ? 907 LYS A N 1 ATOM 7226 C CA . LYS A 1 907 ? 22.698 44.373 -22.279 1.00 24.18 ? 907 LYS A CA 1 ATOM 7227 C C . LYS A 1 907 ? 22.653 44.194 -20.767 1.00 22.92 ? 907 LYS A C 1 ATOM 7228 O O . LYS A 1 907 ? 22.325 45.136 -20.055 1.00 26.47 ? 907 LYS A O 1 ATOM 7229 C CB . LYS A 1 907 ? 21.295 44.211 -22.876 1.00 28.57 ? 907 LYS A CB 1 ATOM 7230 C CG . LYS A 1 907 ? 21.228 44.614 -24.341 1.00 35.86 ? 907 LYS A CG 1 ATOM 7231 C CD . LYS A 1 907 ? 19.809 44.402 -24.859 1.00 40.34 ? 907 LYS A CD 1 ATOM 7232 C CE . LYS A 1 907 ? 19.653 44.842 -26.302 1.00 42.42 ? 907 LYS A CE 1 ATOM 7233 N NZ . LYS A 1 907 ? 18.240 44.588 -26.752 1.00 46.87 ? 907 LYS A NZ 1 ATOM 7234 N N . LEU A 1 908 ? 22.989 43.012 -20.255 1.00 22.33 ? 908 LEU A N 1 ATOM 7235 C CA . LEU A 1 908 ? 22.930 42.810 -18.802 1.00 23.54 ? 908 LEU A CA 1 ATOM 7236 C C . LEU A 1 908 ? 24.248 43.141 -18.096 1.00 19.78 ? 908 LEU A C 1 ATOM 7237 O O . LEU A 1 908 ? 24.322 43.106 -16.862 1.00 21.69 ? 908 LEU A O 1 ATOM 7238 C CB . LEU A 1 908 ? 22.521 41.361 -18.468 1.00 25.67 ? 908 LEU A CB 1 ATOM 7239 C CG . LEU A 1 908 ? 21.111 40.991 -18.955 1.00 28.11 ? 908 LEU A CG 1 ATOM 7240 C CD1 . LEU A 1 908 ? 20.891 39.490 -18.765 1.00 29.13 ? 908 LEU A CD1 1 ATOM 7241 C CD2 . LEU A 1 908 ? 20.057 41.792 -18.190 1.00 29.64 ? 908 LEU A CD2 1 ATOM 7242 N N . HIS A 1 909 ? 25.283 43.490 -18.841 1.00 18.97 ? 909 HIS A N 1 ATOM 7243 C CA . HIS A 1 909 ? 26.570 43.780 -18.212 1.00 16.89 ? 909 HIS A CA 1 ATOM 7244 C C . HIS A 1 909 ? 26.499 45.152 -17.559 1.00 16.47 ? 909 HIS A C 1 ATOM 7245 O O . HIS A 1 909 ? 25.993 46.105 -18.159 1.00 17.35 ? 909 HIS A O 1 ATOM 7246 C CB . HIS A 1 909 ? 27.674 43.755 -19.259 1.00 16.52 ? 909 HIS A CB 1 ATOM 7247 C CG . HIS A 1 909 ? 29.026 43.501 -18.692 1.00 17.45 ? 909 HIS A CG 1 ATOM 7248 N ND1 . HIS A 1 909 ? 29.700 44.447 -17.943 1.00 16.64 ? 909 HIS A ND1 1 ATOM 7249 C CD2 . HIS A 1 909 ? 29.835 42.415 -18.754 1.00 15.28 ? 909 HIS A CD2 1 ATOM 7250 C CE1 . HIS A 1 909 ? 30.869 43.951 -17.586 1.00 16.75 ? 909 HIS A CE1 1 ATOM 7251 N NE2 . HIS A 1 909 ? 30.982 42.720 -18.073 1.00 17.52 ? 909 HIS A NE2 1 ATOM 7252 N N . PRO A 1 910 ? 27.003 45.282 -16.326 1.00 14.17 ? 910 PRO A N 1 ATOM 7253 C CA . PRO A 1 910 ? 26.940 46.598 -15.670 1.00 14.32 ? 910 PRO A CA 1 ATOM 7254 C C . PRO A 1 910 ? 28.043 47.598 -16.029 1.00 12.87 ? 910 PRO A C 1 ATOM 7255 O O . PRO A 1 910 ? 28.016 48.716 -15.492 1.00 14.22 ? 910 PRO A O 1 ATOM 7256 C CB . PRO A 1 910 ? 26.992 46.276 -14.173 1.00 16.85 ? 910 PRO A CB 1 ATOM 7257 C CG . PRO A 1 910 ? 27.029 44.800 -14.074 1.00 17.37 ? 910 PRO A CG 1 ATOM 7258 C CD . PRO A 1 910 ? 27.482 44.245 -15.392 1.00 15.30 ? 910 PRO A CD 1 ATOM 7259 N N . ALA A 1 911 ? 28.999 47.206 -16.872 1.00 13.24 ? 911 ALA A N 1 ATOM 7260 C CA . ALA A 1 911 ? 30.091 48.108 -17.237 1.00 15.20 ? 911 ALA A CA 1 ATOM 7261 C C . ALA A 1 911 ? 30.004 48.576 -18.665 1.00 14.71 ? 911 ALA A C 1 ATOM 7262 O O . ALA A 1 911 ? 29.266 47.998 -19.484 1.00 16.29 ? 911 ALA A O 1 ATOM 7263 C CB . ALA A 1 911 ? 31.446 47.413 -17.053 1.00 13.80 ? 911 ALA A CB 1 ATOM 7264 N N . GLY A 1 912 ? 30.766 49.631 -18.946 1.00 14.05 ? 912 GLY A N 1 ATOM 7265 C CA . GLY A 1 912 ? 30.958 50.101 -20.304 1.00 14.63 ? 912 GLY A CA 1 ATOM 7266 C C . GLY A 1 912 ? 32.454 50.352 -20.462 1.00 14.89 ? 912 GLY A C 1 ATOM 7267 O O . GLY A 1 912 ? 33.193 50.435 -19.472 1.00 15.49 ? 912 GLY A O 1 ATOM 7268 N N . TYR A 1 913 ? 32.921 50.517 -21.693 1.00 12.95 ? 913 TYR A N 1 ATOM 7269 C CA . TYR A 1 913 ? 34.323 50.708 -21.998 1.00 14.04 ? 913 TYR A CA 1 ATOM 7270 C C . TYR A 1 913 ? 34.482 51.726 -23.095 1.00 13.56 ? 913 TYR A C 1 ATOM 7271 O O . TYR A 1 913 ? 33.692 51.762 -24.064 1.00 14.85 ? 913 TYR A O 1 ATOM 7272 C CB . TYR A 1 913 ? 34.972 49.385 -22.467 1.00 15.21 ? 913 TYR A CB 1 ATOM 7273 C CG . TYR A 1 913 ? 34.953 48.340 -21.392 1.00 13.25 ? 913 TYR A CG 1 ATOM 7274 C CD1 . TYR A 1 913 ? 35.848 48.403 -20.346 1.00 13.48 ? 913 TYR A CD1 1 ATOM 7275 C CD2 . TYR A 1 913 ? 33.991 47.349 -21.373 1.00 14.01 ? 913 TYR A CD2 1 ATOM 7276 C CE1 . TYR A 1 913 ? 35.795 47.519 -19.296 1.00 12.88 ? 913 TYR A CE1 1 ATOM 7277 C CE2 . TYR A 1 913 ? 33.900 46.444 -20.321 1.00 15.50 ? 913 TYR A CE2 1 ATOM 7278 C CZ . TYR A 1 913 ? 34.814 46.549 -19.286 1.00 15.61 ? 913 TYR A CZ 1 ATOM 7279 O OH . TYR A 1 913 ? 34.695 45.687 -18.206 1.00 16.45 ? 913 TYR A OH 1 ATOM 7280 N N . LEU A 1 914 ? 35.557 52.483 -22.989 1.00 12.70 ? 914 LEU A N 1 ATOM 7281 C CA . LEU A 1 914 ? 35.891 53.491 -23.976 1.00 13.27 ? 914 LEU A CA 1 ATOM 7282 C C . LEU A 1 914 ? 36.479 52.862 -25.222 1.00 14.35 ? 914 LEU A C 1 ATOM 7283 O O . LEU A 1 914 ? 36.977 51.731 -25.225 1.00 15.70 ? 914 LEU A O 1 ATOM 7284 C CB . LEU A 1 914 ? 36.984 54.450 -23.428 1.00 14.08 ? 914 LEU A CB 1 ATOM 7285 C CG . LEU A 1 914 ? 36.510 55.342 -22.269 1.00 13.45 ? 914 LEU A CG 1 ATOM 7286 C CD1 . LEU A 1 914 ? 37.610 56.361 -22.013 1.00 15.10 ? 914 LEU A CD1 1 ATOM 7287 C CD2 . LEU A 1 914 ? 35.212 56.099 -22.552 1.00 14.77 ? 914 LEU A CD2 1 ATOM 7288 N N . THR A 1 915 ? 36.411 53.649 -26.293 1.00 15.51 ? 915 THR A N 1 ATOM 7289 C CA . THR A 1 915 ? 37.083 53.314 -27.525 1.00 15.33 ? 915 THR A CA 1 ATOM 7290 C C . THR A 1 915 ? 38.496 53.892 -27.397 1.00 16.37 ? 915 THR A C 1 ATOM 7291 O O . THR A 1 915 ? 38.794 54.706 -26.488 1.00 15.84 ? 915 THR A O 1 ATOM 7292 C CB . THR A 1 915 ? 36.456 54.005 -28.718 1.00 16.00 ? 915 THR A CB 1 ATOM 7293 O OG1 . THR A 1 915 ? 36.458 55.416 -28.441 1.00 18.78 ? 915 THR A OG1 1 ATOM 7294 C CG2 . THR A 1 915 ? 35.033 53.483 -29.000 1.00 18.47 ? 915 THR A CG2 1 ATOM 7295 N N . SER A 1 916 ? 39.384 53.494 -28.298 1.00 14.97 ? 916 SER A N 1 ATOM 7296 C CA . SER A 1 916 ? 40.734 53.992 -28.341 1.00 15.64 ? 916 SER A CA 1 ATOM 7297 C C . SER A 1 916 ? 40.759 55.519 -28.438 1.00 15.02 ? 916 SER A C 1 ATOM 7298 O O . SER A 1 916 ? 41.486 56.202 -27.685 1.00 14.39 ? 916 SER A O 1 ATOM 7299 C CB . SER A 1 916 ? 41.473 53.432 -29.564 1.00 18.18 ? 916 SER A CB 1 ATOM 7300 O OG . SER A 1 916 ? 42.633 54.195 -29.789 1.00 26.16 ? 916 SER A OG 1 ATOM 7301 N N . ALA A 1 917 ? 39.965 56.092 -29.332 1.00 15.13 ? 917 ALA A N 1 ATOM 7302 C CA . ALA A 1 917 ? 39.983 57.532 -29.467 1.00 13.23 ? 917 ALA A CA 1 ATOM 7303 C C . ALA A 1 917 ? 39.541 58.267 -28.225 1.00 12.80 ? 917 ALA A C 1 ATOM 7304 O O . ALA A 1 917 ? 40.110 59.322 -27.902 1.00 14.82 ? 917 ALA A O 1 ATOM 7305 C CB . ALA A 1 917 ? 39.062 57.943 -30.624 1.00 15.78 ? 917 ALA A CB 1 ATOM 7306 N N . ALA A 1 918 ? 38.521 57.737 -27.525 1.00 13.72 ? 918 ALA A N 1 ATOM 7307 C CA . ALA A 1 918 ? 38.065 58.435 -26.317 1.00 12.60 ? 918 ALA A CA 1 ATOM 7308 C C . ALA A 1 918 ? 39.077 58.294 -25.195 1.00 13.94 ? 918 ALA A C 1 ATOM 7309 O O . ALA A 1 918 ? 39.302 59.259 -24.451 1.00 13.15 ? 918 ALA A O 1 ATOM 7310 C CB . ALA A 1 918 ? 36.704 57.923 -25.906 1.00 15.14 ? 918 ALA A CB 1 ATOM 7311 N N . HIS A 1 919 ? 39.691 57.131 -25.085 1.00 12.07 ? 919 HIS A N 1 ATOM 7312 C CA . HIS A 1 919 ? 40.731 56.955 -24.077 1.00 11.69 ? 919 HIS A CA 1 ATOM 7313 C C . HIS A 1 919 ? 41.903 57.896 -24.340 1.00 12.46 ? 919 HIS A C 1 ATOM 7314 O O . HIS A 1 919 ? 42.408 58.546 -23.413 1.00 13.09 ? 919 HIS A O 1 ATOM 7315 C CB . HIS A 1 919 ? 41.196 55.504 -24.081 1.00 13.73 ? 919 HIS A CB 1 ATOM 7316 C CG . HIS A 1 919 ? 42.343 55.265 -23.153 1.00 16.27 ? 919 HIS A CG 1 ATOM 7317 N ND1 . HIS A 1 919 ? 43.601 54.940 -23.600 1.00 19.56 ? 919 HIS A ND1 1 ATOM 7318 C CD2 . HIS A 1 919 ? 42.421 55.339 -21.802 1.00 17.89 ? 919 HIS A CD2 1 ATOM 7319 C CE1 . HIS A 1 919 ? 44.415 54.810 -22.563 1.00 18.37 ? 919 HIS A CE1 1 ATOM 7320 N NE2 . HIS A 1 919 ? 43.731 55.051 -21.465 1.00 17.43 ? 919 HIS A NE2 1 ATOM 7321 N N . LYS A 1 920 ? 42.363 57.984 -25.593 1.00 12.27 ? 920 LYS A N 1 ATOM 7322 C CA . LYS A 1 920 ? 43.466 58.877 -25.904 1.00 13.50 ? 920 LYS A CA 1 ATOM 7323 C C . LYS A 1 920 ? 43.047 60.316 -25.634 1.00 12.31 ? 920 LYS A C 1 ATOM 7324 O O . LYS A 1 920 ? 43.870 61.109 -25.158 1.00 13.33 ? 920 LYS A O 1 ATOM 7325 C CB . LYS A 1 920 ? 43.940 58.714 -27.347 1.00 17.42 ? 920 LYS A CB 1 ATOM 7326 C CG . LYS A 1 920 ? 44.859 57.496 -27.487 1.00 20.59 ? 920 LYS A CG 1 ATOM 7327 C CD . LYS A 1 920 ? 45.559 57.444 -28.859 1.00 24.38 ? 920 LYS A CD 1 ATOM 7328 C CE . LYS A 1 920 ? 46.544 56.294 -28.936 1.00 26.82 ? 920 LYS A CE 1 ATOM 7329 N NZ . LYS A 1 920 ? 47.703 56.394 -28.024 1.00 23.95 ? 920 LYS A NZ 1 ATOM 7330 N N . ALA A 1 921 ? 41.798 60.666 -25.917 1.00 12.93 ? 921 ALA A N 1 ATOM 7331 C CA . ALA A 1 921 ? 41.341 62.037 -25.655 1.00 12.74 ? 921 ALA A CA 1 ATOM 7332 C C . ALA A 1 921 ? 41.405 62.325 -24.141 1.00 12.96 ? 921 ALA A C 1 ATOM 7333 O O . ALA A 1 921 ? 41.739 63.438 -23.709 1.00 12.74 ? 921 ALA A O 1 ATOM 7334 C CB . ALA A 1 921 ? 39.908 62.227 -26.224 1.00 12.11 ? 921 ALA A CB 1 ATOM 7335 N N . SER A 1 922 ? 41.050 61.331 -23.339 1.00 12.80 ? 922 SER A N 1 ATOM 7336 C CA . SER A 1 922 ? 41.113 61.520 -21.890 1.00 11.52 ? 922 SER A CA 1 ATOM 7337 C C . SER A 1 922 ? 42.541 61.718 -21.464 1.00 13.89 ? 922 SER A C 1 ATOM 7338 O O . SER A 1 922 ? 42.814 62.597 -20.641 1.00 12.80 ? 922 SER A O 1 ATOM 7339 C CB . SER A 1 922 ? 40.505 60.307 -21.189 1.00 11.56 ? 922 SER A CB 1 ATOM 7340 O OG . SER A 1 922 ? 40.643 60.477 -19.763 1.00 12.69 ? 922 SER A OG 1 ATOM 7341 N N . GLN A 1 923 ? 43.470 60.929 -22.013 1.00 12.73 ? 923 GLN A N 1 ATOM 7342 C CA . GLN A 1 923 ? 44.891 61.080 -21.680 1.00 12.08 ? 923 GLN A CA 1 ATOM 7343 C C . GLN A 1 923 ? 45.393 62.478 -22.108 1.00 12.47 ? 923 GLN A C 1 ATOM 7344 O O . GLN A 1 923 ? 46.248 63.042 -21.443 1.00 13.84 ? 923 GLN A O 1 ATOM 7345 C CB . GLN A 1 923 ? 45.725 60.000 -22.379 1.00 13.66 ? 923 GLN A CB 1 ATOM 7346 C CG . GLN A 1 923 ? 45.436 58.610 -21.849 1.00 12.49 ? 923 GLN A CG 1 ATOM 7347 C CD . GLN A 1 923 ? 46.387 57.604 -22.444 1.00 13.62 ? 923 GLN A CD 1 ATOM 7348 O OE1 . GLN A 1 923 ? 46.561 57.554 -23.674 1.00 15.10 ? 923 GLN A OE1 1 ATOM 7349 N NE2 . GLN A 1 923 ? 47.050 56.805 -21.571 1.00 14.52 ? 923 GLN A NE2 1 ATOM 7350 N N . SER A 1 924 ? 44.864 63.038 -23.204 1.00 12.31 ? 924 SER A N 1 ATOM 7351 C CA . SER A 1 924 ? 45.322 64.340 -23.641 1.00 15.02 ? 924 SER A CA 1 ATOM 7352 C C . SER A 1 924 ? 44.905 65.401 -22.639 1.00 14.17 ? 924 SER A C 1 ATOM 7353 O O . SER A 1 924 ? 45.558 66.433 -22.518 1.00 16.53 ? 924 SER A O 1 ATOM 7354 C CB . SER A 1 924 ? 44.723 64.679 -24.998 1.00 17.08 ? 924 SER A CB 1 ATOM 7355 O OG A SER A 1 924 ? 43.384 65.156 -24.873 0.50 24.68 ? 924 SER A OG 1 ATOM 7356 O OG B SER A 1 924 ? 45.273 63.861 -26.030 0.50 24.68 ? 924 SER A OG 1 ATOM 7357 N N . LEU A 1 925 ? 43.804 65.163 -21.926 1.00 14.54 ? 925 LEU A N 1 ATOM 7358 C CA . LEU A 1 925 ? 43.338 66.131 -20.929 1.00 13.94 ? 925 LEU A CA 1 ATOM 7359 C C . LEU A 1 925 ? 44.085 65.978 -19.599 1.00 14.56 ? 925 LEU A C 1 ATOM 7360 O O . LEU A 1 925 ? 44.480 66.978 -18.995 1.00 14.67 ? 925 LEU A O 1 ATOM 7361 C CB . LEU A 1 925 ? 41.835 65.963 -20.633 1.00 12.93 ? 925 LEU A CB 1 ATOM 7362 C CG . LEU A 1 925 ? 40.918 66.249 -21.823 1.00 12.29 ? 925 LEU A CG 1 ATOM 7363 C CD1 . LEU A 1 925 ? 39.464 65.977 -21.365 1.00 14.68 ? 925 LEU A CD1 1 ATOM 7364 C CD2 . LEU A 1 925 ? 41.100 67.722 -22.300 1.00 14.06 ? 925 LEU A CD2 1 ATOM 7365 N N . LEU A 1 926 ? 44.265 64.731 -19.168 1.00 13.21 ? 926 LEU A N 1 ATOM 7366 C CA . LEU A 1 926 ? 44.871 64.484 -17.862 1.00 13.30 ? 926 LEU A CA 1 ATOM 7367 C C . LEU A 1 926 ? 46.368 64.467 -17.830 1.00 14.50 ? 926 LEU A C 1 ATOM 7368 O O . LEU A 1 926 ? 46.955 64.867 -16.807 1.00 14.14 ? 926 LEU A O 1 ATOM 7369 C CB . LEU A 1 926 ? 44.308 63.173 -17.285 1.00 13.34 ? 926 LEU A CB 1 ATOM 7370 C CG . LEU A 1 926 ? 42.785 63.223 -17.051 1.00 16.39 ? 926 LEU A CG 1 ATOM 7371 C CD1 . LEU A 1 926 ? 42.351 61.858 -16.433 1.00 16.44 ? 926 LEU A CD1 1 ATOM 7372 C CD2 . LEU A 1 926 ? 42.387 64.390 -16.090 1.00 17.30 ? 926 LEU A CD2 1 ATOM 7373 N N . ASP A 1 927 ? 47.004 63.978 -18.888 1.00 11.99 ? 927 ASP A N 1 ATOM 7374 C CA . ASP A 1 927 ? 48.447 63.923 -18.928 1.00 12.56 ? 927 ASP A CA 1 ATOM 7375 C C . ASP A 1 927 ? 49.034 64.452 -20.218 1.00 11.06 ? 927 ASP A C 1 ATOM 7376 O O . ASP A 1 927 ? 49.600 63.721 -21.031 1.00 13.58 ? 927 ASP A O 1 ATOM 7377 C CB . ASP A 1 927 ? 48.921 62.486 -18.630 1.00 12.41 ? 927 ASP A CB 1 ATOM 7378 C CG . ASP A 1 927 ? 48.563 62.040 -17.207 1.00 12.02 ? 927 ASP A CG 1 ATOM 7379 O OD1 . ASP A 1 927 ? 49.261 62.451 -16.224 1.00 13.66 ? 927 ASP A OD1 1 ATOM 7380 O OD2 . ASP A 1 927 ? 47.560 61.329 -17.081 1.00 14.26 ? 927 ASP A OD2 1 ATOM 7381 N N . PRO A 1 928 ? 48.859 65.749 -20.430 1.00 12.78 ? 928 PRO A N 1 ATOM 7382 C CA . PRO A 1 928 ? 49.383 66.391 -21.640 1.00 11.60 ? 928 PRO A CA 1 ATOM 7383 C C . PRO A 1 928 ? 50.897 66.419 -21.626 1.00 13.86 ? 928 PRO A C 1 ATOM 7384 O O . PRO A 1 928 ? 51.536 66.120 -20.609 1.00 14.08 ? 928 PRO A O 1 ATOM 7385 C CB . PRO A 1 928 ? 48.866 67.834 -21.533 1.00 13.75 ? 928 PRO A CB 1 ATOM 7386 C CG . PRO A 1 928 ? 48.817 68.076 -20.051 1.00 15.74 ? 928 PRO A CG 1 ATOM 7387 C CD . PRO A 1 928 ? 48.290 66.718 -19.478 1.00 13.86 ? 928 PRO A CD 1 ATOM 7388 N N . LEU A 1 929 ? 51.494 66.748 -22.762 1.00 15.23 ? 929 LEU A N 1 ATOM 7389 C CA . LEU A 1 929 ? 52.912 66.967 -22.779 1.00 13.49 ? 929 LEU A CA 1 ATOM 7390 C C . LEU A 1 929 ? 53.223 68.153 -21.875 1.00 12.61 ? 929 LEU A C 1 ATOM 7391 O O . LEU A 1 929 ? 52.464 69.109 -21.783 1.00 16.03 ? 929 LEU A O 1 ATOM 7392 C CB . LEU A 1 929 ? 53.397 67.328 -24.196 1.00 13.86 ? 929 LEU A CB 1 ATOM 7393 C CG . LEU A 1 929 ? 53.192 66.301 -25.300 1.00 13.08 ? 929 LEU A CG 1 ATOM 7394 C CD1 . LEU A 1 929 ? 53.721 66.950 -26.622 1.00 14.47 ? 929 LEU A CD1 1 ATOM 7395 C CD2 . LEU A 1 929 ? 54.037 65.020 -24.998 1.00 12.05 ? 929 LEU A CD2 1 ATOM 7396 N N . ASP A 1 930 ? 54.337 68.081 -21.168 1.00 11.88 ? 930 ASP A N 1 ATOM 7397 C CA . ASP A 1 930 ? 54.791 69.198 -20.361 1.00 11.43 ? 930 ASP A CA 1 ATOM 7398 C C . ASP A 1 930 ? 55.730 70.063 -21.215 1.00 13.58 ? 930 ASP A C 1 ATOM 7399 O O . ASP A 1 930 ? 56.481 69.544 -22.044 1.00 14.56 ? 930 ASP A O 1 ATOM 7400 C CB . ASP A 1 930 ? 55.518 68.684 -19.121 1.00 11.98 ? 930 ASP A CB 1 ATOM 7401 C CG . ASP A 1 930 ? 54.714 67.666 -18.380 1.00 14.30 ? 930 ASP A CG 1 ATOM 7402 O OD1 . ASP A 1 930 ? 53.649 68.091 -17.882 1.00 17.16 ? 930 ASP A OD1 1 ATOM 7403 O OD2 . ASP A 1 930 ? 55.138 66.492 -18.320 1.00 14.04 ? 930 ASP A OD2 1 ATOM 7404 N N . LYS A 1 931 ? 55.690 71.359 -21.004 1.00 13.41 ? 931 LYS A N 1 ATOM 7405 C CA . LYS A 1 931 ? 56.486 72.291 -21.801 1.00 13.25 ? 931 LYS A CA 1 ATOM 7406 C C . LYS A 1 931 ? 57.435 73.074 -20.935 1.00 13.24 ? 931 LYS A C 1 ATOM 7407 O O . LYS A 1 931 ? 57.031 73.704 -19.959 1.00 15.14 ? 931 LYS A O 1 ATOM 7408 C CB . LYS A 1 931 ? 55.538 73.245 -22.556 1.00 13.91 ? 931 LYS A CB 1 ATOM 7409 C CG . LYS A 1 931 ? 54.539 72.552 -23.522 1.00 16.89 ? 931 LYS A CG 1 ATOM 7410 C CD . LYS A 1 931 ? 53.638 73.584 -24.210 1.00 20.19 ? 931 LYS A CD 1 ATOM 7411 C CE . LYS A 1 931 ? 52.689 74.170 -23.207 1.00 21.70 ? 931 LYS A CE 1 ATOM 7412 N NZ . LYS A 1 931 ? 51.965 75.308 -23.764 1.00 24.21 ? 931 LYS A NZ 1 ATOM 7413 N N . PHE A 1 932 ? 58.695 73.126 -21.344 1.00 13.11 ? 932 PHE A N 1 ATOM 7414 C CA . PHE A 1 932 ? 59.728 73.833 -20.599 1.00 12.34 ? 932 PHE A CA 1 ATOM 7415 C C . PHE A 1 932 ? 60.410 74.869 -21.483 1.00 12.78 ? 932 PHE A C 1 ATOM 7416 O O . PHE A 1 932 ? 60.746 74.568 -22.641 1.00 13.27 ? 932 PHE A O 1 ATOM 7417 C CB . PHE A 1 932 ? 60.802 72.869 -20.111 1.00 13.06 ? 932 PHE A CB 1 ATOM 7418 C CG . PHE A 1 932 ? 60.296 71.786 -19.207 1.00 15.07 ? 932 PHE A CG 1 ATOM 7419 C CD1 . PHE A 1 932 ? 59.718 70.637 -19.724 1.00 14.63 ? 932 PHE A CD1 1 ATOM 7420 C CD2 . PHE A 1 932 ? 60.447 71.927 -17.827 1.00 15.77 ? 932 PHE A CD2 1 ATOM 7421 C CE1 . PHE A 1 932 ? 59.276 69.604 -18.899 1.00 14.68 ? 932 PHE A CE1 1 ATOM 7422 C CE2 . PHE A 1 932 ? 60.020 70.905 -16.962 1.00 16.58 ? 932 PHE A CE2 1 ATOM 7423 C CZ . PHE A 1 932 ? 59.433 69.753 -17.509 1.00 16.52 ? 932 PHE A CZ 1 ATOM 7424 N N . ILE A 1 933 ? 60.593 76.077 -20.970 1.00 13.15 ? 933 ILE A N 1 ATOM 7425 C CA . ILE A 1 933 ? 61.274 77.139 -21.744 1.00 13.98 ? 933 ILE A CA 1 ATOM 7426 C C . ILE A 1 933 ? 62.634 77.373 -21.088 1.00 16.36 ? 933 ILE A C 1 ATOM 7427 O O . ILE A 1 933 ? 62.694 77.679 -19.893 1.00 14.16 ? 933 ILE A O 1 ATOM 7428 C CB . ILE A 1 933 ? 60.478 78.451 -21.688 1.00 15.11 ? 933 ILE A CB 1 ATOM 7429 C CG1 . ILE A 1 933 ? 59.056 78.214 -22.250 1.00 14.34 ? 933 ILE A CG1 1 ATOM 7430 C CG2 . ILE A 1 933 ? 61.223 79.552 -22.467 1.00 13.10 ? 933 ILE A CG2 1 ATOM 7431 C CD1 . ILE A 1 933 ? 58.168 79.427 -22.063 1.00 14.99 ? 933 ILE A CD1 1 ATOM 7432 N N . PHE A 1 934 ? 63.737 77.235 -21.845 1.00 13.97 ? 934 PHE A N 1 ATOM 7433 C CA . PHE A 1 934 ? 65.054 77.456 -21.240 1.00 15.21 ? 934 PHE A CA 1 ATOM 7434 C C . PHE A 1 934 ? 65.113 78.928 -20.765 1.00 15.09 ? 934 PHE A C 1 ATOM 7435 O O . PHE A 1 934 ? 64.776 79.866 -21.503 1.00 15.68 ? 934 PHE A O 1 ATOM 7436 C CB . PHE A 1 934 ? 66.179 77.111 -22.247 1.00 15.57 ? 934 PHE A CB 1 ATOM 7437 C CG . PHE A 1 934 ? 67.541 77.152 -21.641 1.00 17.94 ? 934 PHE A CG 1 ATOM 7438 C CD1 . PHE A 1 934 ? 67.967 76.140 -20.807 1.00 17.76 ? 934 PHE A CD1 1 ATOM 7439 C CD2 . PHE A 1 934 ? 68.370 78.259 -21.851 1.00 19.06 ? 934 PHE A CD2 1 ATOM 7440 C CE1 . PHE A 1 934 ? 69.212 76.215 -20.170 1.00 20.35 ? 934 PHE A CE1 1 ATOM 7441 C CE2 . PHE A 1 934 ? 69.617 78.356 -21.225 1.00 20.67 ? 934 PHE A CE2 1 ATOM 7442 C CZ . PHE A 1 934 ? 70.041 77.331 -20.377 1.00 21.01 ? 934 PHE A CZ 1 ATOM 7443 N N . ALA A 1 935 ? 65.576 79.145 -19.535 1.00 16.34 ? 935 ALA A N 1 ATOM 7444 C CA . ALA A 1 935 ? 65.544 80.500 -18.998 1.00 18.97 ? 935 ALA A CA 1 ATOM 7445 C C . ALA A 1 935 ? 66.666 81.430 -19.434 1.00 22.30 ? 935 ALA A C 1 ATOM 7446 O O . ALA A 1 935 ? 66.411 82.615 -19.750 1.00 26.19 ? 935 ALA A O 1 ATOM 7447 C CB . ALA A 1 935 ? 65.480 80.451 -17.468 1.00 23.06 ? 935 ALA A CB 1 ATOM 7448 N N . GLU A 1 936 ? 67.881 80.903 -19.493 1.00 20.43 ? 936 GLU A N 1 ATOM 7449 C CA . GLU A 1 936 ? 69.066 81.704 -19.852 1.00 22.04 ? 936 GLU A CA 1 ATOM 7450 C C . GLU A 1 936 ? 69.166 81.920 -21.354 1.00 20.29 ? 936 GLU A C 1 ATOM 7451 O O . GLU A 1 936 ? 68.380 81.376 -22.125 1.00 20.16 ? 936 GLU A O 1 ATOM 7452 C CB . GLU A 1 936 ? 70.354 81.013 -19.359 1.00 24.20 ? 936 GLU A CB 1 ATOM 7453 C CG . GLU A 1 936 ? 70.478 80.750 -17.830 1.00 30.94 ? 936 GLU A CG 1 ATOM 7454 C CD . GLU A 1 936 ? 71.558 79.659 -17.497 1.00 33.59 ? 936 GLU A CD 1 ATOM 7455 O OE1 . GLU A 1 936 ? 71.332 78.445 -17.765 1.00 33.11 ? 936 GLU A OE1 1 ATOM 7456 O OE2 . GLU A 1 936 ? 72.652 80.008 -16.985 1.00 35.75 ? 936 GLU A OE2 1 ATOM 7457 N N . ASN A 1 937 ? 70.148 82.694 -21.785 1.00 21.29 ? 937 ASN A N 1 ATOM 7458 C CA . ASN A 1 937 ? 70.263 82.930 -23.200 1.00 18.90 ? 937 ASN A CA 1 ATOM 7459 C C . ASN A 1 937 ? 70.849 81.791 -23.980 1.00 18.30 ? 937 ASN A C 1 ATOM 7460 O O . ASN A 1 937 ? 70.471 81.589 -25.138 1.00 19.63 ? 937 ASN A O 1 ATOM 7461 C CB . ASN A 1 937 ? 71.100 84.171 -23.457 1.00 18.39 ? 937 ASN A CB 1 ATOM 7462 C CG . ASN A 1 937 ? 70.388 85.432 -23.050 1.00 24.63 ? 937 ASN A CG 1 ATOM 7463 O OD1 . ASN A 1 937 ? 69.143 85.480 -22.985 1.00 25.66 ? 937 ASN A OD1 1 ATOM 7464 N ND2 . ASN A 1 937 ? 71.168 86.484 -22.796 1.00 28.74 ? 937 ASN A ND2 1 ATOM 7465 N N . GLU A 1 938 ? 71.778 81.054 -23.372 1.00 19.65 ? 938 GLU A N 1 ATOM 7466 C CA . GLU A 1 938 ? 72.358 79.941 -24.104 1.00 22.28 ? 938 GLU A CA 1 ATOM 7467 C C . GLU A 1 938 ? 72.452 78.696 -23.260 1.00 19.06 ? 938 GLU A C 1 ATOM 7468 O O . GLU A 1 938 ? 72.864 78.753 -22.128 1.00 21.96 ? 938 GLU A O 1 ATOM 7469 C CB . GLU A 1 938 ? 73.754 80.306 -24.613 1.00 27.37 ? 938 GLU A CB 1 ATOM 7470 C CG . GLU A 1 938 ? 74.437 79.136 -25.272 1.00 32.85 ? 938 GLU A CG 1 ATOM 7471 C CD . GLU A 1 938 ? 75.632 79.552 -26.122 1.00 37.36 ? 938 GLU A CD 1 ATOM 7472 O OE1 . GLU A 1 938 ? 76.439 80.390 -25.657 1.00 39.85 ? 938 GLU A OE1 1 ATOM 7473 O OE2 . GLU A 1 938 ? 75.752 79.018 -27.252 1.00 41.18 ? 938 GLU A OE2 1 ATOM 7474 N N . TRP A 1 939 ? 72.088 77.573 -23.851 1.00 22.05 ? 939 TRP A N 1 ATOM 7475 C CA . TRP A 1 939 ? 72.161 76.301 -23.135 1.00 21.37 ? 939 TRP A CA 1 ATOM 7476 C C . TRP A 1 939 ? 73.368 75.528 -23.664 1.00 22.01 ? 939 TRP A C 1 ATOM 7477 O O . TRP A 1 939 ? 73.276 74.882 -24.702 1.00 25.02 ? 939 TRP A O 1 ATOM 7478 C CB . TRP A 1 939 ? 70.854 75.547 -23.389 1.00 21.77 ? 939 TRP A CB 1 ATOM 7479 C CG . TRP A 1 939 ? 70.723 74.207 -22.734 1.00 18.07 ? 939 TRP A CG 1 ATOM 7480 C CD1 . TRP A 1 939 ? 71.604 73.579 -21.875 1.00 19.34 ? 939 TRP A CD1 1 ATOM 7481 C CD2 . TRP A 1 939 ? 69.639 73.306 -22.936 1.00 16.87 ? 939 TRP A CD2 1 ATOM 7482 N NE1 . TRP A 1 939 ? 71.110 72.324 -21.544 1.00 17.68 ? 939 TRP A NE1 1 ATOM 7483 C CE2 . TRP A 1 939 ? 69.911 72.138 -22.190 1.00 14.97 ? 939 TRP A CE2 1 ATOM 7484 C CE3 . TRP A 1 939 ? 68.457 73.371 -23.683 1.00 14.93 ? 939 TRP A CE3 1 ATOM 7485 C CZ2 . TRP A 1 939 ? 69.039 71.043 -22.177 1.00 16.43 ? 939 TRP A CZ2 1 ATOM 7486 C CZ3 . TRP A 1 939 ? 67.585 72.293 -23.670 1.00 16.65 ? 939 TRP A CZ3 1 ATOM 7487 C CH2 . TRP A 1 939 ? 67.880 71.140 -22.927 1.00 15.56 ? 939 TRP A CH2 1 ATOM 7488 N N . ILE A 1 940 ? 74.488 75.589 -22.946 1.00 25.39 ? 940 ILE A N 1 ATOM 7489 C CA . ILE A 1 940 ? 75.683 74.872 -23.398 1.00 26.97 ? 940 ILE A CA 1 ATOM 7490 C C . ILE A 1 940 ? 75.549 73.353 -23.156 1.00 25.50 ? 940 ILE A C 1 ATOM 7491 O O . ILE A 1 940 ? 75.112 72.926 -22.098 1.00 26.03 ? 940 ILE A O 1 ATOM 7492 C CB . ILE A 1 940 ? 76.925 75.417 -22.678 1.00 27.95 ? 940 ILE A CB 1 ATOM 7493 C CG1 . ILE A 1 940 ? 77.131 76.883 -23.064 1.00 30.62 ? 940 ILE A CG1 1 ATOM 7494 C CG2 . ILE A 1 940 ? 78.156 74.584 -23.057 1.00 28.90 ? 940 ILE A CG2 1 ATOM 7495 C CD1 . ILE A 1 940 ? 77.355 77.781 -21.880 1.00 34.36 ? 940 ILE A CD1 1 ATOM 7496 N N . GLY A 1 941 ? 75.915 72.547 -24.142 1.00 24.99 ? 941 GLY A N 1 ATOM 7497 C CA . GLY A 1 941 ? 75.810 71.109 -23.956 1.00 24.48 ? 941 GLY A CA 1 ATOM 7498 C C . GLY A 1 941 ? 74.418 70.519 -24.174 1.00 23.99 ? 941 GLY A C 1 ATOM 7499 O O . GLY A 1 941 ? 74.206 69.316 -23.937 1.00 21.94 ? 941 GLY A O 1 ATOM 7500 N N . ALA A 1 942 ? 73.471 71.333 -24.649 1.00 21.37 ? 942 ALA A N 1 ATOM 7501 C CA . ALA A 1 942 ? 72.120 70.845 -24.898 1.00 20.94 ? 942 ALA A CA 1 ATOM 7502 C C . ALA A 1 942 ? 72.045 69.641 -25.818 1.00 20.17 ? 942 ALA A C 1 ATOM 7503 O O . ALA A 1 942 ? 72.762 69.562 -26.819 1.00 21.16 ? 942 ALA A O 1 ATOM 7504 C CB . ALA A 1 942 ? 71.251 71.980 -25.458 1.00 21.74 ? 942 ALA A CB 1 ATOM 7505 N N . GLN A 1 943 ? 71.151 68.708 -25.492 1.00 20.53 ? 943 GLN A N 1 ATOM 7506 C CA . GLN A 1 943 ? 70.908 67.528 -26.276 1.00 21.08 ? 943 GLN A CA 1 ATOM 7507 C C . GLN A 1 943 ? 69.488 67.565 -26.832 1.00 18.86 ? 943 GLN A C 1 ATOM 7508 O O . GLN A 1 943 ? 68.587 68.235 -26.251 1.00 20.15 ? 943 GLN A O 1 ATOM 7509 C CB . GLN A 1 943 ? 71.128 66.288 -25.419 1.00 23.12 ? 943 GLN A CB 1 ATOM 7510 C CG . GLN A 1 943 ? 72.503 66.300 -24.756 1.00 29.58 ? 943 GLN A CG 1 ATOM 7511 C CD . GLN A 1 943 ? 72.736 65.031 -23.966 1.00 34.13 ? 943 GLN A CD 1 ATOM 7512 O OE1 . GLN A 1 943 ? 71.822 64.565 -23.254 1.00 37.12 ? 943 GLN A OE1 1 ATOM 7513 N NE2 . GLN A 1 943 ? 73.945 64.457 -24.074 1.00 35.23 ? 943 GLN A NE2 1 ATOM 7514 N N . GLY A 1 944 ? 69.255 66.838 -27.923 1.00 19.76 ? 944 GLY A N 1 ATOM 7515 C CA . GLY A 1 944 ? 67.985 66.891 -28.604 1.00 19.82 ? 944 GLY A CA 1 ATOM 7516 C C . GLY A 1 944 ? 66.879 65.972 -28.157 1.00 18.60 ? 944 GLY A C 1 ATOM 7517 O O . GLY A 1 944 ? 65.711 66.209 -28.436 1.00 19.35 ? 944 GLY A O 1 ATOM 7518 N N . GLN A 1 945 ? 67.231 64.910 -27.455 1.00 17.85 ? 945 GLN A N 1 ATOM 7519 C CA . GLN A 1 945 ? 66.200 63.951 -27.094 1.00 19.18 ? 945 GLN A CA 1 ATOM 7520 C C . GLN A 1 945 ? 66.644 63.045 -25.958 1.00 19.94 ? 945 GLN A C 1 ATOM 7521 O O . GLN A 1 945 ? 67.832 62.833 -25.728 1.00 19.28 ? 945 GLN A O 1 ATOM 7522 C CB . GLN A 1 945 ? 65.893 63.106 -28.334 1.00 20.33 ? 945 GLN A CB 1 ATOM 7523 C CG . GLN A 1 945 ? 64.715 62.143 -28.246 1.00 23.69 ? 945 GLN A CG 1 ATOM 7524 C CD . GLN A 1 945 ? 64.644 61.235 -29.478 1.00 23.60 ? 945 GLN A CD 1 ATOM 7525 O OE1 . GLN A 1 945 ? 63.829 61.442 -30.384 1.00 26.65 ? 945 GLN A OE1 1 ATOM 7526 N NE2 . GLN A 1 945 ? 65.509 60.241 -29.515 1.00 26.49 ? 945 GLN A NE2 1 ATOM 7527 N N . PHE A 1 946 ? 65.659 62.568 -25.194 1.00 15.58 ? 946 PHE A N 1 ATOM 7528 C CA . PHE A 1 946 ? 65.942 61.586 -24.141 1.00 15.21 ? 946 PHE A CA 1 ATOM 7529 C C . PHE A 1 946 ? 64.833 60.572 -24.232 1.00 14.68 ? 946 PHE A C 1 ATOM 7530 O O . PHE A 1 946 ? 63.689 60.934 -24.423 1.00 15.67 ? 946 PHE A O 1 ATOM 7531 C CB . PHE A 1 946 ? 65.914 62.226 -22.750 1.00 15.76 ? 946 PHE A CB 1 ATOM 7532 C CG . PHE A 1 946 ? 65.783 61.219 -21.631 1.00 16.55 ? 946 PHE A CG 1 ATOM 7533 C CD1 . PHE A 1 946 ? 66.836 60.381 -21.298 1.00 17.52 ? 946 PHE A CD1 1 ATOM 7534 C CD2 . PHE A 1 946 ? 64.572 61.102 -20.950 1.00 17.04 ? 946 PHE A CD2 1 ATOM 7535 C CE1 . PHE A 1 946 ? 66.681 59.421 -20.275 1.00 18.30 ? 946 PHE A CE1 1 ATOM 7536 C CE2 . PHE A 1 946 ? 64.397 60.150 -19.934 1.00 17.64 ? 946 PHE A CE2 1 ATOM 7537 C CZ . PHE A 1 946 ? 65.431 59.315 -19.593 1.00 17.99 ? 946 PHE A CZ 1 ATOM 7538 N N . GLY A 1 947 ? 65.169 59.289 -24.098 1.00 15.17 ? 947 GLY A N 1 ATOM 7539 C CA . GLY A 1 947 ? 64.173 58.246 -24.149 1.00 16.67 ? 947 GLY A CA 1 ATOM 7540 C C . GLY A 1 947 ? 63.841 57.656 -25.491 1.00 17.60 ? 947 GLY A C 1 ATOM 7541 O O . GLY A 1 947 ? 62.889 56.908 -25.589 1.00 17.75 ? 947 GLY A O 1 ATOM 7542 N N . GLY A 1 948 ? 64.624 57.979 -26.532 1.00 20.52 ? 948 GLY A N 1 ATOM 7543 C CA . GLY A 1 948 ? 64.347 57.438 -27.852 1.00 19.57 ? 948 GLY A CA 1 ATOM 7544 C C . GLY A 1 948 ? 64.372 55.911 -27.860 1.00 21.77 ? 948 GLY A C 1 ATOM 7545 O O . GLY A 1 948 ? 63.728 55.272 -28.708 1.00 24.31 ? 948 GLY A O 1 ATOM 7546 N N . ASP A 1 949 ? 65.111 55.325 -26.917 1.00 22.94 ? 949 ASP A N 1 ATOM 7547 C CA . ASP A 1 949 ? 65.188 53.874 -26.808 1.00 25.68 ? 949 ASP A CA 1 ATOM 7548 C C . ASP A 1 949 ? 64.176 53.259 -25.844 1.00 24.23 ? 949 ASP A C 1 ATOM 7549 O O . ASP A 1 949 ? 64.191 52.035 -25.611 1.00 24.91 ? 949 ASP A O 1 ATOM 7550 C CB . ASP A 1 949 ? 66.616 53.457 -26.406 1.00 29.25 ? 949 ASP A CB 1 ATOM 7551 C CG . ASP A 1 949 ? 67.027 53.962 -25.005 1.00 35.12 ? 949 ASP A CG 1 ATOM 7552 O OD1 . ASP A 1 949 ? 66.575 55.044 -24.538 1.00 35.42 ? 949 ASP A OD1 1 ATOM 7553 O OD2 . ASP A 1 949 ? 67.843 53.266 -24.350 1.00 40.87 ? 949 ASP A OD2 1 ATOM 7554 N N . HIS A 1 950 ? 63.295 54.080 -25.255 1.00 21.33 ? 950 HIS A N 1 ATOM 7555 C CA . HIS A 1 950 ? 62.290 53.515 -24.339 1.00 17.29 ? 950 HIS A CA 1 ATOM 7556 C C . HIS A 1 950 ? 61.212 52.775 -25.173 1.00 17.11 ? 950 HIS A C 1 ATOM 7557 O O . HIS A 1 950 ? 60.814 53.230 -26.242 1.00 20.95 ? 950 HIS A O 1 ATOM 7558 C CB . HIS A 1 950 ? 61.562 54.615 -23.574 1.00 17.49 ? 950 HIS A CB 1 ATOM 7559 C CG . HIS A 1 950 ? 62.393 55.421 -22.633 1.00 17.40 ? 950 HIS A CG 1 ATOM 7560 N ND1 . HIS A 1 950 ? 63.640 55.064 -22.156 1.00 19.59 ? 950 HIS A ND1 1 ATOM 7561 C CD2 . HIS A 1 950 ? 62.075 56.580 -22.016 1.00 13.48 ? 950 HIS A CD2 1 ATOM 7562 C CE1 . HIS A 1 950 ? 64.045 55.969 -21.279 1.00 15.58 ? 950 HIS A CE1 1 ATOM 7563 N NE2 . HIS A 1 950 ? 63.109 56.899 -21.181 1.00 21.46 ? 950 HIS A NE2 1 ATOM 7564 N N . PRO A 1 951 ? 60.717 51.631 -24.688 1.00 18.87 ? 951 PRO A N 1 ATOM 7565 C CA . PRO A 1 951 ? 59.696 50.862 -25.400 1.00 19.75 ? 951 PRO A CA 1 ATOM 7566 C C . PRO A 1 951 ? 58.403 51.659 -25.549 1.00 19.53 ? 951 PRO A C 1 ATOM 7567 O O . PRO A 1 951 ? 57.971 52.334 -24.595 1.00 19.97 ? 951 PRO A O 1 ATOM 7568 C CB . PRO A 1 951 ? 59.487 49.627 -24.495 1.00 21.21 ? 951 PRO A CB 1 ATOM 7569 C CG . PRO A 1 951 ? 60.779 49.490 -23.828 1.00 24.11 ? 951 PRO A CG 1 ATOM 7570 C CD . PRO A 1 951 ? 61.173 50.917 -23.485 1.00 21.78 ? 951 PRO A CD 1 ATOM 7571 N N . SER A 1 952 ? 57.775 51.579 -26.711 1.00 19.33 ? 952 SER A N 1 ATOM 7572 C CA . SER A 1 952 ? 56.531 52.291 -26.928 1.00 17.96 ? 952 SER A CA 1 ATOM 7573 C C . SER A 1 952 ? 55.440 51.234 -26.757 1.00 18.90 ? 952 SER A C 1 ATOM 7574 O O . SER A 1 952 ? 55.137 50.430 -27.685 1.00 20.37 ? 952 SER A O 1 ATOM 7575 C CB . SER A 1 952 ? 56.499 52.921 -28.318 1.00 17.35 ? 952 SER A CB 1 ATOM 7576 O OG . SER A 1 952 ? 55.404 53.824 -28.463 1.00 20.87 ? 952 SER A OG 1 ATOM 7577 N N . ALA A 1 953 ? 54.858 51.217 -25.559 1.00 18.54 ? 953 ALA A N 1 ATOM 7578 C CA . ALA A 1 953 ? 53.878 50.230 -25.167 1.00 17.53 ? 953 ALA A CA 1 ATOM 7579 C C . ALA A 1 953 ? 52.515 50.346 -25.791 1.00 15.49 ? 953 ALA A C 1 ATOM 7580 O O . ALA A 1 953 ? 52.115 51.396 -26.267 1.00 16.81 ? 953 ALA A O 1 ATOM 7581 C CB . ALA A 1 953 ? 53.753 50.238 -23.620 1.00 18.87 ? 953 ALA A CB 1 ATOM 7582 N N . ARG A 1 954 ? 51.795 49.236 -25.790 1.00 15.71 ? 954 ARG A N 1 ATOM 7583 C CA . ARG A 1 954 ? 50.456 49.165 -26.315 1.00 17.65 ? 954 ARG A CA 1 ATOM 7584 C C . ARG A 1 954 ? 49.616 50.306 -25.713 1.00 16.30 ? 954 ARG A C 1 ATOM 7585 O O . ARG A 1 954 ? 49.750 50.640 -24.522 1.00 15.73 ? 954 ARG A O 1 ATOM 7586 C CB . ARG A 1 954 ? 49.886 47.799 -25.968 1.00 21.14 ? 954 ARG A CB 1 ATOM 7587 C CG . ARG A 1 954 ? 48.580 47.532 -26.660 1.00 33.61 ? 954 ARG A CG 1 ATOM 7588 C CD . ARG A 1 954 ? 48.493 46.065 -27.092 1.00 37.54 ? 954 ARG A CD 1 ATOM 7589 N NE . ARG A 1 954 ? 47.562 45.303 -26.263 1.00 42.89 ? 954 ARG A NE 1 ATOM 7590 C CZ . ARG A 1 954 ? 46.318 45.694 -26.026 1.00 43.93 ? 954 ARG A CZ 1 ATOM 7591 N NH1 . ARG A 1 954 ? 45.882 46.838 -26.543 1.00 46.50 ? 954 ARG A NH1 1 ATOM 7592 N NH2 . ARG A 1 954 ? 45.493 44.935 -25.314 1.00 44.00 ? 954 ARG A NH2 1 ATOM 7593 N N . GLU A 1 955 ? 48.712 50.855 -26.513 1.00 15.04 ? 955 GLU A N 1 ATOM 7594 C CA . GLU A 1 955 ? 47.933 52.027 -26.125 1.00 16.11 ? 955 GLU A CA 1 ATOM 7595 C C . GLU A 1 955 ? 47.089 51.905 -24.863 1.00 14.63 ? 955 GLU A C 1 ATOM 7596 O O . GLU A 1 955 ? 46.777 52.944 -24.236 1.00 15.87 ? 955 GLU A O 1 ATOM 7597 C CB . GLU A 1 955 ? 47.044 52.494 -27.303 1.00 19.07 ? 955 GLU A CB 1 ATOM 7598 C CG . GLU A 1 955 ? 45.953 51.511 -27.642 1.00 20.02 ? 955 GLU A CG 1 ATOM 7599 C CD . GLU A 1 955 ? 45.048 51.983 -28.743 1.00 25.65 ? 955 GLU A CD 1 ATOM 7600 O OE1 . GLU A 1 955 ? 44.864 53.209 -28.887 1.00 31.76 ? 955 GLU A OE1 1 ATOM 7601 O OE2 . GLU A 1 955 ? 44.514 51.105 -29.455 1.00 27.42 ? 955 GLU A OE2 1 ATOM 7602 N N . ASP A 1 956 ? 46.700 50.684 -24.493 1.00 12.75 ? 956 ASP A N 1 ATOM 7603 C CA . ASP A 1 956 ? 45.866 50.543 -23.300 1.00 13.84 ? 956 ASP A CA 1 ATOM 7604 C C . ASP A 1 956 ? 46.694 50.434 -22.024 1.00 14.32 ? 956 ASP A C 1 ATOM 7605 O O . ASP A 1 956 ? 46.114 50.356 -20.949 1.00 16.13 ? 956 ASP A O 1 ATOM 7606 C CB . ASP A 1 956 ? 44.869 49.360 -23.418 1.00 14.34 ? 956 ASP A CB 1 ATOM 7607 C CG . ASP A 1 956 ? 45.524 48.038 -23.758 1.00 18.25 ? 956 ASP A CG 1 ATOM 7608 O OD1 . ASP A 1 956 ? 46.741 48.011 -23.999 1.00 21.11 ? 956 ASP A OD1 1 ATOM 7609 O OD2 . ASP A 1 956 ? 44.785 47.026 -23.789 1.00 20.94 ? 956 ASP A OD2 1 ATOM 7610 N N . LEU A 1 957 ? 48.010 50.436 -22.134 1.00 14.12 ? 957 LEU A N 1 ATOM 7611 C CA . LEU A 1 957 ? 48.875 50.292 -20.947 1.00 13.12 ? 957 LEU A CA 1 ATOM 7612 C C . LEU A 1 957 ? 49.449 51.636 -20.542 1.00 12.59 ? 957 LEU A C 1 ATOM 7613 O O . LEU A 1 957 ? 49.877 52.415 -21.404 1.00 15.77 ? 957 LEU A O 1 ATOM 7614 C CB . LEU A 1 957 ? 50.032 49.338 -21.290 1.00 13.17 ? 957 LEU A CB 1 ATOM 7615 C CG . LEU A 1 957 ? 50.901 48.901 -20.106 1.00 16.87 ? 957 LEU A CG 1 ATOM 7616 C CD1 . LEU A 1 957 ? 50.047 48.189 -19.050 1.00 20.35 ? 957 LEU A CD1 1 ATOM 7617 C CD2 . LEU A 1 957 ? 52.012 47.950 -20.618 1.00 18.99 ? 957 LEU A CD2 1 ATOM 7618 N N . ASP A 1 958 ? 49.465 51.918 -19.233 1.00 13.19 ? 958 ASP A N 1 ATOM 7619 C CA . ASP A 1 958 ? 50.108 53.144 -18.755 1.00 12.87 ? 958 ASP A CA 1 ATOM 7620 C C . ASP A 1 958 ? 51.046 52.844 -17.609 1.00 11.24 ? 958 ASP A C 1 ATOM 7621 O O . ASP A 1 958 ? 50.819 51.868 -16.857 1.00 13.16 ? 958 ASP A O 1 ATOM 7622 C CB . ASP A 1 958 ? 49.047 54.145 -18.272 1.00 12.55 ? 958 ASP A CB 1 ATOM 7623 C CG . ASP A 1 958 ? 49.604 55.552 -18.082 1.00 12.87 ? 958 ASP A CG 1 ATOM 7624 O OD1 . ASP A 1 958 ? 50.720 55.846 -18.568 1.00 13.67 ? 958 ASP A OD1 1 ATOM 7625 O OD2 . ASP A 1 958 ? 48.887 56.349 -17.420 1.00 15.53 ? 958 ASP A OD2 1 ATOM 7626 N N . VAL A 1 959 ? 52.109 53.639 -17.498 1.00 11.61 ? 959 VAL A N 1 ATOM 7627 C CA . VAL A 1 959 ? 52.979 53.572 -16.318 1.00 11.68 ? 959 VAL A CA 1 ATOM 7628 C C . VAL A 1 959 ? 52.415 54.705 -15.473 1.00 12.56 ? 959 VAL A C 1 ATOM 7629 O O . VAL A 1 959 ? 52.823 55.849 -15.572 1.00 13.08 ? 959 VAL A O 1 ATOM 7630 C CB . VAL A 1 959 ? 54.433 53.814 -16.687 1.00 12.39 ? 959 VAL A CB 1 ATOM 7631 C CG1 . VAL A 1 959 ? 55.295 53.952 -15.378 1.00 12.43 ? 959 VAL A CG1 1 ATOM 7632 C CG2 . VAL A 1 959 ? 54.936 52.611 -17.506 1.00 15.11 ? 959 VAL A CG2 1 ATOM 7633 N N . SER A 1 960 ? 51.443 54.379 -14.621 1.00 11.50 ? 960 SER A N 1 ATOM 7634 C CA . SER A 1 960 ? 50.745 55.377 -13.806 1.00 11.25 ? 960 SER A CA 1 ATOM 7635 C C . SER A 1 960 ? 51.662 56.081 -12.828 1.00 13.44 ? 960 SER A C 1 ATOM 7636 O O . SER A 1 960 ? 51.520 57.288 -12.573 1.00 14.36 ? 960 SER A O 1 ATOM 7637 C CB . SER A 1 960 ? 49.636 54.680 -13.031 1.00 12.45 ? 960 SER A CB 1 ATOM 7638 O OG . SER A 1 960 ? 48.803 53.881 -13.892 1.00 15.13 ? 960 SER A OG 1 ATOM 7639 N N . VAL A 1 961 ? 52.592 55.289 -12.284 1.00 12.83 ? 961 VAL A N 1 ATOM 7640 C CA . VAL A 1 961 ? 53.575 55.816 -11.336 1.00 12.86 ? 961 VAL A CA 1 ATOM 7641 C C . VAL A 1 961 ? 54.976 55.252 -11.640 1.00 12.13 ? 961 VAL A C 1 ATOM 7642 O O . VAL A 1 961 ? 55.136 54.051 -11.914 1.00 12.60 ? 961 VAL A O 1 ATOM 7643 C CB . VAL A 1 961 ? 53.252 55.377 -9.886 1.00 12.29 ? 961 VAL A CB 1 ATOM 7644 C CG1 . VAL A 1 961 ? 54.395 55.812 -8.917 1.00 13.93 ? 961 VAL A CG1 1 ATOM 7645 C CG2 . VAL A 1 961 ? 51.913 56.004 -9.423 1.00 14.73 ? 961 VAL A CG2 1 ATOM 7646 N N . MET A 1 962 ? 55.968 56.150 -11.634 1.00 12.52 ? 962 MET A N 1 ATOM 7647 C CA . MET A 1 962 ? 57.370 55.731 -11.652 1.00 11.41 ? 962 MET A CA 1 ATOM 7648 C C . MET A 1 962 ? 57.947 56.554 -10.500 1.00 11.75 ? 962 MET A C 1 ATOM 7649 O O . MET A 1 962 ? 57.897 57.790 -10.493 1.00 13.43 ? 962 MET A O 1 ATOM 7650 C CB . MET A 1 962 ? 58.106 56.076 -12.967 1.00 13.80 ? 962 MET A CB 1 ATOM 7651 C CG . MET A 1 962 ? 59.593 55.717 -12.877 1.00 13.56 ? 962 MET A CG 1 ATOM 7652 S SD . MET A 1 962 ? 60.348 56.024 -14.494 1.00 14.79 ? 962 MET A SD 1 ATOM 7653 C CE . MET A 1 962 ? 62.094 55.519 -14.135 1.00 17.72 ? 962 MET A CE 1 ATOM 7654 N N . ARG A 1 963 ? 58.511 55.851 -9.503 1.00 12.49 ? 963 ARG A N 1 ATOM 7655 C CA . ARG A 1 963 ? 59.055 56.506 -8.321 1.00 11.52 ? 963 ARG A CA 1 ATOM 7656 C C . ARG A 1 963 ? 60.292 55.841 -7.786 1.00 11.82 ? 963 ARG A C 1 ATOM 7657 O O . ARG A 1 963 ? 60.237 54.666 -7.435 1.00 13.15 ? 963 ARG A O 1 ATOM 7658 C CB . ARG A 1 963 ? 57.980 56.482 -7.200 1.00 13.19 ? 963 ARG A CB 1 ATOM 7659 C CG . ARG A 1 963 ? 58.438 57.089 -5.844 1.00 13.59 ? 963 ARG A CG 1 ATOM 7660 C CD . ARG A 1 963 ? 57.353 56.948 -4.716 1.00 14.95 ? 963 ARG A CD 1 ATOM 7661 N NE . ARG A 1 963 ? 56.147 57.657 -5.155 1.00 12.86 ? 963 ARG A NE 1 ATOM 7662 C CZ . ARG A 1 963 ? 54.918 57.148 -5.092 1.00 12.75 ? 963 ARG A CZ 1 ATOM 7663 N NH1 . ARG A 1 963 ? 54.638 55.943 -4.568 1.00 12.61 ? 963 ARG A NH1 1 ATOM 7664 N NH2 . ARG A 1 963 ? 53.945 57.824 -5.717 1.00 13.20 ? 963 ARG A NH2 1 ATOM 7665 N N . ARG A 1 964 ? 61.398 56.578 -7.698 1.00 12.63 ? 964 ARG A N 1 ATOM 7666 C CA . ARG A 1 964 ? 62.606 55.968 -7.081 1.00 13.42 ? 964 ARG A CA 1 ATOM 7667 C C . ARG A 1 964 ? 62.283 55.920 -5.564 1.00 13.38 ? 964 ARG A C 1 ATOM 7668 O O . ARG A 1 964 ? 61.852 56.902 -4.961 1.00 13.68 ? 964 ARG A O 1 ATOM 7669 C CB . ARG A 1 964 ? 63.814 56.855 -7.356 1.00 13.20 ? 964 ARG A CB 1 ATOM 7670 C CG . ARG A 1 964 ? 65.089 56.234 -6.762 1.00 14.09 ? 964 ARG A CG 1 ATOM 7671 C CD . ARG A 1 964 ? 66.367 56.913 -7.246 1.00 14.26 ? 964 ARG A CD 1 ATOM 7672 N NE . ARG A 1 964 ? 66.562 56.743 -8.678 1.00 15.03 ? 964 ARG A NE 1 ATOM 7673 C CZ . ARG A 1 964 ? 67.435 55.922 -9.244 1.00 15.96 ? 964 ARG A CZ 1 ATOM 7674 N NH1 . ARG A 1 964 ? 68.228 55.142 -8.487 1.00 18.61 ? 964 ARG A NH1 1 ATOM 7675 N NH2 . ARG A 1 964 ? 67.562 55.887 -10.574 1.00 18.87 ? 964 ARG A NH2 1 ATOM 7676 N N . LEU A 1 965 ? 62.531 54.747 -4.985 1.00 14.07 ? 965 LEU A N 1 ATOM 7677 C CA . LEU A 1 965 ? 62.159 54.497 -3.589 1.00 12.78 ? 965 LEU A CA 1 ATOM 7678 C C . LEU A 1 965 ? 63.324 54.627 -2.615 1.00 15.91 ? 965 LEU A C 1 ATOM 7679 O O . LEU A 1 965 ? 63.111 54.575 -1.397 1.00 17.42 ? 965 LEU A O 1 ATOM 7680 C CB . LEU A 1 965 ? 61.582 53.093 -3.478 1.00 14.89 ? 965 LEU A CB 1 ATOM 7681 C CG . LEU A 1 965 ? 60.348 52.824 -4.376 1.00 14.50 ? 965 LEU A CG 1 ATOM 7682 C CD1 . LEU A 1 965 ? 59.978 51.344 -4.342 1.00 15.41 ? 965 LEU A CD1 1 ATOM 7683 C CD2 . LEU A 1 965 ? 59.179 53.671 -3.914 1.00 15.60 ? 965 LEU A CD2 1 ATOM 7684 N N . THR A 1 966 ? 64.528 54.780 -3.153 1.00 15.29 ? 966 THR A N 1 ATOM 7685 C CA . THR A 1 966 ? 65.732 54.883 -2.313 1.00 15.69 ? 966 THR A CA 1 ATOM 7686 C C . THR A 1 966 ? 66.441 56.205 -2.507 1.00 15.46 ? 966 THR A C 1 ATOM 7687 O O . THR A 1 966 ? 66.438 56.761 -3.608 1.00 15.40 ? 966 THR A O 1 ATOM 7688 C CB . THR A 1 966 ? 66.753 53.797 -2.711 1.00 15.65 ? 966 THR A CB 1 ATOM 7689 O OG1 . THR A 1 966 ? 66.825 53.722 -4.142 1.00 17.61 ? 966 THR A OG1 1 ATOM 7690 C CG2 . THR A 1 966 ? 66.343 52.435 -2.175 1.00 17.75 ? 966 THR A CG2 1 ATOM 7691 N N . LYS A 1 967 ? 67.096 56.682 -1.440 1.00 16.14 ? 967 LYS A N 1 ATOM 7692 C CA . LYS A 1 967 ? 67.912 57.879 -1.484 1.00 17.66 ? 967 LYS A CA 1 ATOM 7693 C C . LYS A 1 967 ? 69.312 57.454 -1.990 1.00 16.96 ? 967 LYS A C 1 ATOM 7694 O O . LYS A 1 967 ? 69.596 56.266 -2.162 1.00 16.68 ? 967 LYS A O 1 ATOM 7695 C CB . LYS A 1 967 ? 68.018 58.509 -0.113 1.00 19.65 ? 967 LYS A CB 1 ATOM 7696 C CG . LYS A 1 967 ? 66.672 59.055 0.375 1.00 23.49 ? 967 LYS A CG 1 ATOM 7697 C CD . LYS A 1 967 ? 66.860 59.826 1.649 1.00 27.33 ? 967 LYS A CD 1 ATOM 7698 C CE . LYS A 1 967 ? 65.696 60.776 1.894 1.00 34.04 ? 967 LYS A CE 1 ATOM 7699 N NZ . LYS A 1 967 ? 66.168 61.924 2.747 1.00 37.49 ? 967 LYS A NZ 1 ATOM 7700 N N . SER A 1 968 ? 70.142 58.455 -2.264 1.00 18.07 ? 968 SER A N 1 ATOM 7701 C CA . SER A 1 968 ? 71.440 58.208 -2.880 1.00 19.84 ? 968 SER A CA 1 ATOM 7702 C C . SER A 1 968 ? 72.426 57.349 -2.091 1.00 21.68 ? 968 SER A C 1 ATOM 7703 O O . SER A 1 968 ? 73.257 56.669 -2.696 1.00 24.33 ? 968 SER A O 1 ATOM 7704 C CB . SER A 1 968 ? 72.102 59.548 -3.274 1.00 21.44 ? 968 SER A CB 1 ATOM 7705 O OG . SER A 1 968 ? 72.403 60.329 -2.144 1.00 28.82 ? 968 SER A OG 1 ATOM 7706 N N . SER A 1 969 ? 72.279 57.326 -0.777 1.00 21.57 ? 969 SER A N 1 ATOM 7707 C CA . SER A 1 969 ? 73.222 56.553 0.053 1.00 24.27 ? 969 SER A CA 1 ATOM 7708 C C . SER A 1 969 ? 72.963 55.046 0.027 1.00 23.53 ? 969 SER A C 1 ATOM 7709 O O . SER A 1 969 ? 73.775 54.280 0.527 1.00 23.83 ? 969 SER A O 1 ATOM 7710 C CB . SER A 1 969 ? 73.191 57.052 1.479 1.00 26.54 ? 969 SER A CB 1 ATOM 7711 O OG . SER A 1 969 ? 71.969 56.699 2.095 1.00 34.72 ? 969 SER A OG 1 ATOM 7712 N N . ALA A 1 970 ? 71.843 54.599 -0.541 1.00 20.04 ? 970 ALA A N 1 ATOM 7713 C CA . ALA A 1 970 ? 71.580 53.173 -0.636 1.00 20.22 ? 970 ALA A CA 1 ATOM 7714 C C . ALA A 1 970 ? 72.417 52.469 -1.676 1.00 22.02 ? 970 ALA A C 1 ATOM 7715 O O . ALA A 1 970 ? 72.412 52.823 -2.863 1.00 22.20 ? 970 ALA A O 1 ATOM 7716 C CB . ALA A 1 970 ? 70.073 52.879 -0.940 1.00 20.87 ? 970 ALA A CB 1 ATOM 7717 N N . LYS A 1 971 ? 73.129 51.445 -1.227 1.00 23.65 ? 971 LYS A N 1 ATOM 7718 C CA . LYS A 1 971 ? 73.957 50.634 -2.091 1.00 24.47 ? 971 LYS A CA 1 ATOM 7719 C C . LYS A 1 971 ? 73.104 50.037 -3.210 1.00 23.19 ? 971 LYS A C 1 ATOM 7720 O O . LYS A 1 971 ? 73.502 50.045 -4.368 1.00 24.26 ? 971 LYS A O 1 ATOM 7721 C CB . LYS A 1 971 ? 74.596 49.518 -1.257 1.00 26.11 ? 971 LYS A CB 1 ATOM 7722 C CG A LYS A 1 971 ? 75.738 48.801 -1.931 0.50 31.96 ? 971 LYS A CG 1 ATOM 7723 C CG B LYS A 1 971 ? 75.764 48.825 -2.198 0.50 31.40 ? 971 LYS A CG 1 ATOM 7724 C CD A LYS A 1 971 ? 76.336 47.751 -0.993 0.50 33.83 ? 971 LYS A CD 1 ATOM 7725 C CD B LYS A 1 971 ? 76.697 47.999 -1.308 0.50 34.31 ? 971 LYS A CD 1 ATOM 7726 C CE A LYS A 1 971 ? 76.535 48.295 0.420 0.50 36.04 ? 971 LYS A CE 1 ATOM 7727 C CE B LYS A 1 971 ? 77.722 47.226 -2.132 0.50 35.43 ? 971 LYS A CE 1 ATOM 7728 N NZ A LYS A 1 971 ? 77.302 49.568 0.436 0.50 36.30 ? 971 LYS A NZ 1 ATOM 7729 N NZ B LYS A 1 971 ? 78.647 46.430 -1.272 0.50 38.36 ? 971 LYS A NZ 1 ATOM 7730 N N . THR A 1 972 ? 71.934 49.509 -2.854 1.00 21.04 ? 972 THR A N 1 ATOM 7731 C CA . THR A 1 972 ? 71.038 48.924 -3.844 1.00 22.11 ? 972 THR A CA 1 ATOM 7732 C C . THR A 1 972 ? 69.878 49.897 -4.119 1.00 19.25 ? 972 THR A C 1 ATOM 7733 O O . THR A 1 972 ? 69.025 50.091 -3.266 1.00 20.75 ? 972 THR A O 1 ATOM 7734 C CB . THR A 1 972 ? 70.467 47.569 -3.399 1.00 24.57 ? 972 THR A CB 1 ATOM 7735 O OG1 . THR A 1 972 ? 71.560 46.662 -3.191 1.00 25.92 ? 972 THR A OG1 1 ATOM 7736 C CG2 . THR A 1 972 ? 69.579 46.946 -4.489 1.00 24.03 ? 972 THR A CG2 1 ATOM 7737 N N . GLN A 1 973 ? 69.871 50.525 -5.290 1.00 18.07 ? 973 GLN A N 1 ATOM 7738 C CA . GLN A 1 973 ? 68.771 51.452 -5.623 1.00 16.91 ? 973 GLN A CA 1 ATOM 7739 C C . GLN A 1 973 ? 67.499 50.687 -5.995 1.00 16.87 ? 973 GLN A C 1 ATOM 7740 O O . GLN A 1 973 ? 67.549 49.629 -6.579 1.00 19.03 ? 973 GLN A O 1 ATOM 7741 C CB . GLN A 1 973 ? 69.214 52.340 -6.783 1.00 16.74 ? 973 GLN A CB 1 ATOM 7742 C CG . GLN A 1 973 ? 70.313 53.318 -6.364 1.00 16.54 ? 973 GLN A CG 1 ATOM 7743 C CD . GLN A 1 973 ? 69.869 54.304 -5.344 1.00 18.83 ? 973 GLN A CD 1 ATOM 7744 O OE1 . GLN A 1 973 ? 70.487 54.472 -4.263 1.00 20.54 ? 973 GLN A OE1 1 ATOM 7745 N NE2 . GLN A 1 973 ? 68.789 54.999 -5.662 1.00 14.69 ? 973 GLN A NE2 1 ATOM 7746 N N . ARG A 1 974 ? 66.338 51.271 -5.693 1.00 16.39 ? 974 ARG A N 1 ATOM 7747 C CA . ARG A 1 974 ? 65.083 50.608 -6.012 1.00 16.29 ? 974 ARG A CA 1 ATOM 7748 C C . ARG A 1 974 ? 64.134 51.621 -6.658 1.00 13.79 ? 974 ARG A C 1 ATOM 7749 O O . ARG A 1 974 ? 64.058 52.779 -6.211 1.00 16.01 ? 974 ARG A O 1 ATOM 7750 C CB . ARG A 1 974 ? 64.426 50.064 -4.742 1.00 16.24 ? 974 ARG A CB 1 ATOM 7751 C CG . ARG A 1 974 ? 65.311 49.035 -3.952 1.00 17.36 ? 974 ARG A CG 1 ATOM 7752 C CD . ARG A 1 974 ? 64.741 48.810 -2.519 1.00 20.48 ? 974 ARG A CD 1 ATOM 7753 N NE . ARG A 1 974 ? 63.478 48.076 -2.581 1.00 27.08 ? 974 ARG A NE 1 ATOM 7754 C CZ . ARG A 1 974 ? 62.313 48.476 -2.077 1.00 24.60 ? 974 ARG A CZ 1 ATOM 7755 N NH1 . ARG A 1 974 ? 62.189 49.632 -1.429 1.00 26.85 ? 974 ARG A NH1 1 ATOM 7756 N NH2 . ARG A 1 974 ? 61.251 47.708 -2.255 1.00 23.13 ? 974 ARG A NH2 1 ATOM 7757 N N . VAL A 1 975 ? 63.471 51.174 -7.715 1.00 16.00 ? 975 VAL A N 1 ATOM 7758 C CA . VAL A 1 975 ? 62.528 52.048 -8.405 1.00 15.35 ? 975 VAL A CA 1 ATOM 7759 C C . VAL A 1 975 ? 61.217 51.298 -8.511 1.00 16.33 ? 975 VAL A C 1 ATOM 7760 O O . VAL A 1 975 ? 61.162 50.125 -8.967 1.00 14.70 ? 975 VAL A O 1 ATOM 7761 C CB . VAL A 1 975 ? 63.039 52.409 -9.811 1.00 14.88 ? 975 VAL A CB 1 ATOM 7762 C CG1 . VAL A 1 975 ? 62.002 53.301 -10.542 1.00 15.63 ? 975 VAL A CG1 1 ATOM 7763 C CG2 . VAL A 1 975 ? 64.360 53.176 -9.665 1.00 17.43 ? 975 VAL A CG2 1 ATOM 7764 N N . GLY A 1 976 ? 60.144 51.981 -8.107 1.00 15.69 ? 976 GLY A N 1 ATOM 7765 C CA . GLY A 1 976 ? 58.822 51.387 -8.175 1.00 13.79 ? 976 GLY A CA 1 ATOM 7766 C C . GLY A 1 976 ? 58.010 51.894 -9.346 1.00 13.04 ? 976 GLY A C 1 ATOM 7767 O O . GLY A 1 976 ? 58.087 53.065 -9.738 1.00 14.47 ? 976 GLY A O 1 ATOM 7768 N N . TYR A 1 977 ? 57.239 50.978 -9.885 1.00 12.96 ? 977 TYR A N 1 ATOM 7769 C CA . TYR A 1 977 ? 56.344 51.275 -11.016 1.00 11.61 ? 977 TYR A CA 1 ATOM 7770 C C . TYR A 1 977 ? 54.944 50.767 -10.737 1.00 13.46 ? 977 TYR A C 1 ATOM 7771 O O . TYR A 1 977 ? 54.777 49.657 -10.233 1.00 14.22 ? 977 TYR A O 1 ATOM 7772 C CB . TYR A 1 977 ? 56.808 50.563 -12.301 1.00 13.15 ? 977 TYR A CB 1 ATOM 7773 C CG . TYR A 1 977 ? 58.188 50.927 -12.719 1.00 12.00 ? 977 TYR A CG 1 ATOM 7774 C CD1 . TYR A 1 977 ? 59.316 50.222 -12.229 1.00 14.02 ? 977 TYR A CD1 1 ATOM 7775 C CD2 . TYR A 1 977 ? 58.389 51.978 -13.576 1.00 13.43 ? 977 TYR A CD2 1 ATOM 7776 C CE1 . TYR A 1 977 ? 60.615 50.580 -12.621 1.00 14.99 ? 977 TYR A CE1 1 ATOM 7777 C CE2 . TYR A 1 977 ? 59.680 52.361 -13.969 1.00 15.69 ? 977 TYR A CE2 1 ATOM 7778 C CZ . TYR A 1 977 ? 60.789 51.647 -13.487 1.00 15.12 ? 977 TYR A CZ 1 ATOM 7779 O OH . TYR A 1 977 ? 62.056 52.027 -13.912 1.00 16.77 ? 977 TYR A OH 1 ATOM 7780 N N . VAL A 1 978 ? 53.924 51.589 -11.045 1.00 12.64 ? 978 VAL A N 1 ATOM 7781 C CA . VAL A 1 978 ? 52.574 51.106 -10.997 1.00 12.01 ? 978 VAL A CA 1 ATOM 7782 C C . VAL A 1 978 ? 52.124 51.051 -12.477 1.00 13.62 ? 978 VAL A C 1 ATOM 7783 O O . VAL A 1 978 ? 52.199 52.080 -13.159 1.00 13.16 ? 978 VAL A O 1 ATOM 7784 C CB . VAL A 1 978 ? 51.599 52.027 -10.202 1.00 12.16 ? 978 VAL A CB 1 ATOM 7785 C CG1 . VAL A 1 978 ? 50.173 51.512 -10.361 1.00 14.48 ? 978 VAL A CG1 1 ATOM 7786 C CG2 . VAL A 1 978 ? 52.013 52.071 -8.702 1.00 13.62 ? 978 VAL A CG2 1 ATOM 7787 N N . LEU A 1 979 ? 51.725 49.889 -12.960 1.00 12.40 ? 979 LEU A N 1 ATOM 7788 C CA . LEU A 1 979 ? 51.280 49.697 -14.332 1.00 13.97 ? 979 LEU A CA 1 ATOM 7789 C C . LEU A 1 979 ? 49.805 49.446 -14.340 1.00 14.46 ? 979 LEU A C 1 ATOM 7790 O O . LEU A 1 979 ? 49.304 48.578 -13.612 1.00 16.26 ? 979 LEU A O 1 ATOM 7791 C CB . LEU A 1 979 ? 51.903 48.448 -14.925 1.00 18.40 ? 979 LEU A CB 1 ATOM 7792 C CG . LEU A 1 979 ? 53.322 48.403 -15.401 1.00 26.67 ? 979 LEU A CG 1 ATOM 7793 C CD1 . LEU A 1 979 ? 53.407 47.193 -16.362 1.00 29.40 ? 979 LEU A CD1 1 ATOM 7794 C CD2 . LEU A 1 979 ? 53.665 49.653 -16.167 1.00 27.47 ? 979 LEU A CD2 1 ATOM 7795 N N . HIS A 1 980 ? 49.090 50.200 -15.156 1.00 13.96 ? 980 HIS A N 1 ATOM 7796 C CA . HIS A 1 980 ? 47.665 50.037 -15.278 1.00 14.05 ? 980 HIS A CA 1 ATOM 7797 C C . HIS A 1 980 ? 47.270 49.763 -16.721 1.00 14.48 ? 980 HIS A C 1 ATOM 7798 O O . HIS A 1 980 ? 47.705 50.486 -17.595 1.00 16.00 ? 980 HIS A O 1 ATOM 7799 C CB . HIS A 1 980 ? 46.873 51.292 -14.852 1.00 14.94 ? 980 HIS A CB 1 ATOM 7800 C CG . HIS A 1 980 ? 45.401 51.072 -14.944 1.00 14.43 ? 980 HIS A CG 1 ATOM 7801 N ND1 . HIS A 1 980 ? 44.564 51.638 -15.891 1.00 16.94 ? 980 HIS A ND1 1 ATOM 7802 C CD2 . HIS A 1 980 ? 44.638 50.194 -14.257 1.00 11.34 ? 980 HIS A CD2 1 ATOM 7803 C CE1 . HIS A 1 980 ? 43.352 51.124 -15.769 1.00 12.29 ? 980 HIS A CE1 1 ATOM 7804 N NE2 . HIS A 1 980 ? 43.371 50.242 -14.788 1.00 17.88 ? 980 HIS A NE2 1 ATOM 7805 N N . ARG A 1 981 ? 46.485 48.724 -16.956 1.00 13.62 ? 981 ARG A N 1 ATOM 7806 C CA . ARG A 1 981 ? 46.007 48.475 -18.297 1.00 14.30 ? 981 ARG A CA 1 ATOM 7807 C C . ARG A 1 981 ? 44.514 48.649 -18.251 1.00 13.77 ? 981 ARG A C 1 ATOM 7808 O O . ARG A 1 981 ? 43.823 48.007 -17.465 1.00 14.85 ? 981 ARG A O 1 ATOM 7809 C CB . ARG A 1 981 ? 46.359 47.077 -18.715 1.00 16.86 ? 981 ARG A CB 1 ATOM 7810 C CG . ARG A 1 981 ? 46.043 46.827 -20.168 1.00 20.82 ? 981 ARG A CG 1 ATOM 7811 C CD . ARG A 1 981 ? 46.749 45.545 -20.601 1.00 25.79 ? 981 ARG A CD 1 ATOM 7812 N NE . ARG A 1 981 ? 46.263 45.137 -21.892 1.00 29.88 ? 981 ARG A NE 1 ATOM 7813 C CZ . ARG A 1 981 ? 46.396 43.909 -22.371 1.00 32.12 ? 981 ARG A CZ 1 ATOM 7814 N NH1 . ARG A 1 981 ? 47.011 42.983 -21.652 1.00 31.44 ? 981 ARG A NH1 1 ATOM 7815 N NH2 . ARG A 1 981 ? 45.885 43.600 -23.554 1.00 32.84 ? 981 ARG A NH2 1 ATOM 7816 N N . THR A 1 982 ? 44.000 49.524 -19.106 1.00 13.93 ? 982 THR A N 1 ATOM 7817 C CA . THR A 1 982 ? 42.547 49.736 -19.181 1.00 13.78 ? 982 THR A CA 1 ATOM 7818 C C . THR A 1 982 ? 41.988 48.704 -20.192 1.00 15.04 ? 982 THR A C 1 ATOM 7819 O O . THR A 1 982 ? 42.715 47.773 -20.583 1.00 17.77 ? 982 THR A O 1 ATOM 7820 C CB . THR A 1 982 ? 42.244 51.190 -19.626 1.00 13.53 ? 982 THR A CB 1 ATOM 7821 O OG1 . THR A 1 982 ? 40.853 51.477 -19.474 1.00 14.31 ? 982 THR A OG1 1 ATOM 7822 C CG2 . THR A 1 982 ? 42.666 51.467 -21.073 1.00 15.56 ? 982 THR A CG2 1 ATOM 7823 N N . ASN A 1 983 ? 40.707 48.798 -20.507 1.00 14.44 ? 983 ASN A N 1 ATOM 7824 C CA . ASN A 1 983 ? 40.144 47.895 -21.533 1.00 14.18 ? 983 ASN A CA 1 ATOM 7825 C C . ASN A 1 983 ? 39.443 48.754 -22.560 1.00 15.62 ? 983 ASN A C 1 ATOM 7826 O O . ASN A 1 983 ? 38.537 49.509 -22.223 1.00 16.01 ? 983 ASN A O 1 ATOM 7827 C CB . ASN A 1 983 ? 39.156 46.880 -20.945 1.00 14.20 ? 983 ASN A CB 1 ATOM 7828 C CG . ASN A 1 983 ? 38.674 45.925 -21.984 1.00 12.78 ? 983 ASN A CG 1 ATOM 7829 O OD1 . ASN A 1 983 ? 39.411 45.019 -22.368 1.00 16.67 ? 983 ASN A OD1 1 ATOM 7830 N ND2 . ASN A 1 983 ? 37.465 46.151 -22.477 1.00 15.12 ? 983 ASN A ND2 1 ATOM 7831 N N . LEU A 1 984 ? 39.940 48.679 -23.791 1.00 14.84 ? 984 LEU A N 1 ATOM 7832 C CA . LEU A 1 984 ? 39.353 49.457 -24.897 1.00 15.16 ? 984 LEU A CA 1 ATOM 7833 C C . LEU A 1 984 ? 38.527 48.546 -25.772 1.00 16.73 ? 984 LEU A C 1 ATOM 7834 O O . LEU A 1 984 ? 38.852 47.386 -25.929 1.00 17.45 ? 984 LEU A O 1 ATOM 7835 C CB . LEU A 1 984 ? 40.457 50.084 -25.737 1.00 15.76 ? 984 LEU A CB 1 ATOM 7836 C CG . LEU A 1 984 ? 41.417 50.940 -24.900 1.00 16.71 ? 984 LEU A CG 1 ATOM 7837 C CD1 . LEU A 1 984 ? 42.589 51.389 -25.812 1.00 17.65 ? 984 LEU A CD1 1 ATOM 7838 C CD2 . LEU A 1 984 ? 40.699 52.089 -24.282 1.00 18.37 ? 984 LEU A CD2 1 ATOM 7839 N N . MET A 1 985 ? 37.445 49.072 -26.326 1.00 17.27 ? 985 MET A N 1 ATOM 7840 C CA . MET A 1 985 ? 36.610 48.237 -27.184 1.00 20.98 ? 985 MET A CA 1 ATOM 7841 C C . MET A 1 985 ? 37.276 47.867 -28.484 1.00 20.41 ? 985 MET A C 1 ATOM 7842 O O . MET A 1 985 ? 38.051 48.645 -29.065 1.00 21.46 ? 985 MET A O 1 ATOM 7843 C CB . MET A 1 985 ? 35.310 48.945 -27.513 1.00 21.40 ? 985 MET A CB 1 ATOM 7844 C CG . MET A 1 985 ? 34.400 49.039 -26.337 1.00 25.04 ? 985 MET A CG 1 ATOM 7845 S SD . MET A 1 985 ? 32.734 49.221 -26.875 1.00 27.23 ? 985 MET A SD 1 ATOM 7846 C CE . MET A 1 985 ? 32.832 50.807 -27.603 1.00 27.68 ? 985 MET A CE 1 ATOM 7847 N N . GLN A 1 986 ? 36.982 46.651 -28.939 1.00 20.42 ? 986 GLN A N 1 ATOM 7848 C CA . GLN A 1 986 ? 37.492 46.156 -30.226 1.00 22.36 ? 986 GLN A CA 1 ATOM 7849 C C . GLN A 1 986 ? 36.461 46.663 -31.227 1.00 21.49 ? 986 GLN A C 1 ATOM 7850 O O . GLN A 1 986 ? 35.286 46.306 -31.129 1.00 21.58 ? 986 GLN A O 1 ATOM 7851 C CB . GLN A 1 986 ? 37.504 44.615 -30.242 1.00 26.39 ? 986 GLN A CB 1 ATOM 7852 C CG . GLN A 1 986 ? 38.540 44.006 -29.321 1.00 30.84 ? 986 GLN A CG 1 ATOM 7853 C CD . GLN A 1 986 ? 39.950 44.235 -29.819 1.00 36.25 ? 986 GLN A CD 1 ATOM 7854 O OE1 . GLN A 1 986 ? 40.886 44.359 -29.024 1.00 40.10 ? 986 GLN A OE1 1 ATOM 7855 N NE2 . GLN A 1 986 ? 40.120 44.284 -31.145 1.00 36.02 ? 986 GLN A NE2 1 ATOM 7856 N N . CYS A 1 987 ? 36.893 47.507 -32.162 1.00 22.71 ? 987 CYS A N 1 ATOM 7857 C CA . CYS A 1 987 ? 35.967 48.042 -33.163 1.00 24.63 ? 987 CYS A CA 1 ATOM 7858 C C . CYS A 1 987 ? 36.484 47.853 -34.573 1.00 26.67 ? 987 CYS A C 1 ATOM 7859 O O . CYS A 1 987 ? 36.023 48.551 -35.489 1.00 28.10 ? 987 CYS A O 1 ATOM 7860 C CB . CYS A 1 987 ? 35.689 49.526 -32.951 1.00 24.52 ? 987 CYS A CB 1 ATOM 7861 S SG . CYS A 1 987 ? 35.061 49.911 -31.286 1.00 28.81 ? 987 CYS A SG 1 ATOM 7862 N N . GLY A 1 988 ? 37.439 46.937 -34.736 1.00 26.24 ? 988 GLY A N 1 ATOM 7863 C CA . GLY A 1 988 ? 37.972 46.647 -36.058 1.00 33.92 ? 988 GLY A CA 1 ATOM 7864 C C . GLY A 1 988 ? 39.132 47.486 -36.511 1.00 39.14 ? 988 GLY A C 1 ATOM 7865 O O . GLY A 1 988 ? 39.556 47.374 -37.670 1.00 39.97 ? 988 GLY A O 1 ATOM 7866 N N . THR A 1 989 ? 39.641 48.333 -35.619 1.00 43.40 ? 989 THR A N 1 ATOM 7867 C CA . THR A 1 989 ? 40.784 49.194 -35.931 1.00 48.63 ? 989 THR A CA 1 ATOM 7868 C C . THR A 1 989 ? 42.030 48.400 -35.561 1.00 52.03 ? 989 THR A C 1 ATOM 7869 O O . THR A 1 989 ? 42.401 48.344 -34.392 1.00 52.31 ? 989 THR A O 1 ATOM 7870 C CB . THR A 1 989 ? 40.773 50.471 -35.081 1.00 48.96 ? 989 THR A CB 1 ATOM 7871 O OG1 . THR A 1 989 ? 39.556 51.187 -35.302 1.00 49.57 ? 989 THR A OG1 1 ATOM 7872 C CG2 . THR A 1 989 ? 41.945 51.355 -35.447 1.00 50.70 ? 989 THR A CG2 1 ATOM 7873 N N . PRO A 1 990 ? 42.695 47.773 -36.553 1.00 55.67 ? 990 PRO A N 1 ATOM 7874 C CA . PRO A 1 990 ? 43.895 46.997 -36.218 1.00 57.84 ? 990 PRO A CA 1 ATOM 7875 C C . PRO A 1 990 ? 44.775 47.659 -35.146 1.00 59.79 ? 990 PRO A C 1 ATOM 7876 O O . PRO A 1 990 ? 44.700 47.296 -33.968 1.00 60.37 ? 990 PRO A O 1 ATOM 7877 C CB . PRO A 1 990 ? 44.606 46.858 -37.566 1.00 57.76 ? 990 PRO A CB 1 ATOM 7878 C CG . PRO A 1 990 ? 43.457 46.788 -38.544 1.00 57.60 ? 990 PRO A CG 1 ATOM 7879 C CD . PRO A 1 990 ? 42.541 47.897 -38.019 1.00 56.61 ? 990 PRO A CD 1 ATOM 7880 N N . GLU A 1 991 ? 45.578 48.644 -35.541 1.00 61.55 ? 991 GLU A N 1 ATOM 7881 C CA . GLU A 1 991 ? 46.480 49.308 -34.595 1.00 63.90 ? 991 GLU A CA 1 ATOM 7882 C C . GLU A 1 991 ? 47.333 48.216 -33.957 1.00 64.04 ? 991 GLU A C 1 ATOM 7883 O O . GLU A 1 991 ? 46.912 47.603 -32.980 1.00 64.83 ? 991 GLU A O 1 ATOM 7884 C CB . GLU A 1 991 ? 45.696 50.026 -33.488 1.00 64.54 ? 991 GLU A CB 1 ATOM 7885 C CG . GLU A 1 991 ? 44.796 51.163 -33.956 1.00 66.41 ? 991 GLU A CG 1 ATOM 7886 C CD . GLU A 1 991 ? 44.122 51.890 -32.795 1.00 67.27 ? 991 GLU A CD 1 ATOM 7887 O OE1 . GLU A 1 991 ? 43.378 51.234 -32.024 1.00 66.22 ? 991 GLU A OE1 1 ATOM 7888 O OE2 . GLU A 1 991 ? 44.344 53.118 -32.658 1.00 67.76 ? 991 GLU A OE2 1 ATOM 7889 N N . GLU A 1 992 ? 48.516 47.956 -34.497 1.00 64.06 ? 992 GLU A N 1 ATOM 7890 C CA . GLU A 1 992 ? 49.343 46.912 -33.912 1.00 64.59 ? 992 GLU A CA 1 ATOM 7891 C C . GLU A 1 992 ? 50.793 47.288 -33.727 1.00 63.31 ? 992 GLU A C 1 ATOM 7892 O O . GLU A 1 992 ? 51.107 48.415 -33.327 1.00 62.92 ? 992 GLU A O 1 ATOM 7893 C CB . GLU A 1 992 ? 49.245 45.630 -34.742 1.00 67.39 ? 992 GLU A CB 1 ATOM 7894 C CG . GLU A 1 992 ? 47.884 44.941 -34.641 1.00 70.28 ? 992 GLU A CG 1 ATOM 7895 C CD . GLU A 1 992 ? 47.568 44.438 -33.227 1.00 72.01 ? 992 GLU A CD 1 ATOM 7896 O OE1 . GLU A 1 992 ? 48.470 44.447 -32.355 1.00 72.01 ? 992 GLU A OE1 1 ATOM 7897 O OE2 . GLU A 1 992 ? 46.409 44.023 -32.992 1.00 73.15 ? 992 GLU A OE2 1 ATOM 7898 N N . HIS A 1 993 ? 51.662 46.323 -34.024 1.00 61.90 ? 993 HIS A N 1 ATOM 7899 C CA . HIS A 1 993 ? 53.115 46.458 -33.900 1.00 60.78 ? 993 HIS A CA 1 ATOM 7900 C C . HIS A 1 993 ? 53.604 47.345 -32.756 1.00 57.35 ? 993 HIS A C 1 ATOM 7901 O O . HIS A 1 993 ? 54.071 48.477 -32.980 1.00 57.72 ? 993 HIS A O 1 ATOM 7902 C CB . HIS A 1 993 ? 53.763 46.923 -35.235 1.00 64.30 ? 993 HIS A CB 1 ATOM 7903 C CG . HIS A 1 993 ? 53.254 48.236 -35.761 1.00 67.42 ? 993 HIS A CG 1 ATOM 7904 N ND1 . HIS A 1 993 ? 51.970 48.406 -36.242 1.00 69.16 ? 993 HIS A ND1 1 ATOM 7905 C CD2 . HIS A 1 993 ? 53.875 49.431 -35.925 1.00 68.46 ? 993 HIS A CD2 1 ATOM 7906 C CE1 . HIS A 1 993 ? 51.824 49.644 -36.681 1.00 69.09 ? 993 HIS A CE1 1 ATOM 7907 N NE2 . HIS A 1 993 ? 52.965 50.287 -36.501 1.00 69.57 ? 993 HIS A NE2 1 ATOM 7908 N N . THR A 1 994 ? 53.477 46.844 -31.526 1.00 51.58 ? 994 THR A N 1 ATOM 7909 C CA . THR A 1 994 ? 53.973 47.601 -30.382 1.00 44.76 ? 994 THR A CA 1 ATOM 7910 C C . THR A 1 994 ? 54.943 46.750 -29.583 1.00 41.75 ? 994 THR A C 1 ATOM 7911 O O . THR A 1 994 ? 54.903 45.508 -29.604 1.00 41.73 ? 994 THR A O 1 ATOM 7912 C CB . THR A 1 994 ? 52.843 48.106 -29.448 1.00 43.83 ? 994 THR A CB 1 ATOM 7913 O OG1 . THR A 1 994 ? 52.040 47.005 -29.011 1.00 41.54 ? 994 THR A OG1 1 ATOM 7914 C CG2 . THR A 1 994 ? 51.982 49.128 -30.167 1.00 41.40 ? 994 THR A CG2 1 ATOM 7915 N N . GLN A 1 995 ? 55.817 47.427 -28.857 1.00 36.52 ? 995 GLN A N 1 ATOM 7916 C CA . GLN A 1 995 ? 56.811 46.726 -28.079 1.00 31.80 ? 995 GLN A CA 1 ATOM 7917 C C . GLN A 1 995 ? 56.366 46.394 -26.674 1.00 27.82 ? 995 GLN A C 1 ATOM 7918 O O . GLN A 1 995 ? 55.618 47.128 -26.045 1.00 26.08 ? 995 GLN A O 1 ATOM 7919 C CB . GLN A 1 995 ? 58.051 47.565 -27.963 1.00 31.70 ? 995 GLN A CB 1 ATOM 7920 C CG . GLN A 1 995 ? 58.557 48.085 -29.262 1.00 35.17 ? 995 GLN A CG 1 ATOM 7921 C CD . GLN A 1 995 ? 59.477 49.245 -29.029 1.00 38.76 ? 995 GLN A CD 1 ATOM 7922 O OE1 . GLN A 1 995 ? 59.042 50.399 -29.014 1.00 32.83 ? 995 GLN A OE1 1 ATOM 7923 N NE2 . GLN A 1 995 ? 60.765 48.944 -28.798 1.00 39.00 ? 995 GLN A NE2 1 ATOM 7924 N N . LYS A 1 996 ? 56.859 45.269 -26.191 1.00 25.96 ? 996 LYS A N 1 ATOM 7925 C CA . LYS A 1 996 ? 56.575 44.852 -24.841 1.00 27.11 ? 996 LYS A CA 1 ATOM 7926 C C . LYS A 1 996 ? 57.306 45.824 -23.917 1.00 25.40 ? 996 LYS A C 1 ATOM 7927 O O . LYS A 1 996 ? 58.471 46.195 -24.147 1.00 24.27 ? 996 LYS A O 1 ATOM 7928 C CB . LYS A 1 996 ? 57.107 43.424 -24.630 1.00 31.55 ? 996 LYS A CB 1 ATOM 7929 C CG . LYS A 1 996 ? 56.971 42.900 -23.222 1.00 37.62 ? 996 LYS A CG 1 ATOM 7930 C CD . LYS A 1 996 ? 57.442 41.427 -23.167 1.00 42.38 ? 996 LYS A CD 1 ATOM 7931 C CE . LYS A 1 996 ? 57.177 40.811 -21.797 1.00 45.13 ? 996 LYS A CE 1 ATOM 7932 N NZ . LYS A 1 996 ? 57.743 39.428 -21.715 1.00 49.27 ? 996 LYS A NZ 1 ATOM 7933 N N . LEU A 1 997 ? 56.612 46.242 -22.871 1.00 21.95 ? 997 LEU A N 1 ATOM 7934 C CA . LEU A 1 997 ? 57.244 47.133 -21.916 1.00 21.62 ? 997 LEU A CA 1 ATOM 7935 C C . LEU A 1 997 ? 57.595 46.325 -20.680 1.00 21.29 ? 997 LEU A C 1 ATOM 7936 O O . LEU A 1 997 ? 56.711 45.749 -20.064 1.00 22.08 ? 997 LEU A O 1 ATOM 7937 C CB . LEU A 1 997 ? 56.275 48.273 -21.547 1.00 22.43 ? 997 LEU A CB 1 ATOM 7938 C CG . LEU A 1 997 ? 56.805 49.108 -20.379 1.00 22.75 ? 997 LEU A CG 1 ATOM 7939 C CD1 . LEU A 1 997 ? 58.040 49.916 -20.764 1.00 25.04 ? 997 LEU A CD1 1 ATOM 7940 C CD2 . LEU A 1 997 ? 55.713 50.034 -19.944 1.00 22.96 ? 997 LEU A CD2 1 ATOM 7941 N N . ASP A 1 998 ? 58.888 46.267 -20.354 1.00 18.37 ? 998 ASP A N 1 ATOM 7942 C CA . ASP A 1 998 ? 59.345 45.576 -19.137 1.00 20.94 ? 998 ASP A CA 1 ATOM 7943 C C . ASP A 1 998 ? 59.936 46.676 -18.285 1.00 20.02 ? 998 ASP A C 1 ATOM 7944 O O . ASP A 1 998 ? 61.078 47.123 -18.484 1.00 20.06 ? 998 ASP A O 1 ATOM 7945 C CB . ASP A 1 998 ? 60.415 44.530 -19.472 1.00 21.31 ? 998 ASP A CB 1 ATOM 7946 C CG . ASP A 1 998 ? 61.109 44.006 -18.238 1.00 26.31 ? 998 ASP A CG 1 ATOM 7947 O OD1 . ASP A 1 998 ? 60.577 44.170 -17.106 1.00 22.80 ? 998 ASP A OD1 1 ATOM 7948 O OD2 . ASP A 1 998 ? 62.192 43.406 -18.415 1.00 26.09 ? 998 ASP A OD2 1 ATOM 7949 N N . VAL A 1 999 ? 59.160 47.141 -17.313 1.00 18.94 ? 999 VAL A N 1 ATOM 7950 C CA . VAL A 1 999 ? 59.662 48.237 -16.515 1.00 18.02 ? 999 VAL A CA 1 ATOM 7951 C C . VAL A 1 999 ? 60.913 47.940 -15.722 1.00 17.79 ? 999 VAL A C 1 ATOM 7952 O O . VAL A 1 999 ? 61.677 48.845 -15.405 1.00 18.00 ? 999 VAL A O 1 ATOM 7953 C CB . VAL A 1 999 ? 58.565 48.801 -15.571 1.00 17.46 ? 999 VAL A CB 1 ATOM 7954 C CG1 . VAL A 1 999 ? 57.448 49.376 -16.420 1.00 18.35 ? 999 VAL A CG1 1 ATOM 7955 C CG2 . VAL A 1 999 ? 58.023 47.710 -14.634 1.00 19.56 ? 999 VAL A CG2 1 ATOM 7956 N N . CYS A 1 1000 ? 61.149 46.663 -15.457 1.00 18.61 ? 1000 CYS A N 1 ATOM 7957 C CA . CYS A 1 1000 ? 62.312 46.315 -14.643 1.00 20.26 ? 1000 CYS A CA 1 ATOM 7958 C C . CYS A 1 1000 ? 63.646 46.521 -15.367 1.00 20.91 ? 1000 CYS A C 1 ATOM 7959 O O . CYS A 1 1000 ? 64.684 46.638 -14.721 1.00 22.98 ? 1000 CYS A O 1 ATOM 7960 C CB . CYS A 1 1000 ? 62.168 44.899 -14.077 1.00 23.90 ? 1000 CYS A CB 1 ATOM 7961 S SG . CYS A 1 1000 ? 61.250 44.905 -12.468 1.00 30.23 ? 1000 CYS A SG 1 ATOM 7962 N N . HIS A 1 1001 ? 63.600 46.632 -16.698 1.00 21.81 ? 1001 HIS A N 1 ATOM 7963 C CA . HIS A 1 1001 ? 64.820 46.902 -17.456 1.00 22.33 ? 1001 HIS A CA 1 ATOM 7964 C C . HIS A 1 1001 ? 64.899 48.349 -17.978 1.00 21.42 ? 1001 HIS A C 1 ATOM 7965 O O . HIS A 1 1001 ? 65.745 48.682 -18.806 1.00 23.09 ? 1001 HIS A O 1 ATOM 7966 C CB . HIS A 1 1001 ? 65.000 45.911 -18.605 1.00 22.82 ? 1001 HIS A CB 1 ATOM 7967 C CG . HIS A 1 1001 ? 65.554 44.597 -18.168 1.00 23.88 ? 1001 HIS A CG 1 ATOM 7968 N ND1 . HIS A 1 1001 ? 64.762 43.584 -17.685 1.00 24.19 ? 1001 HIS A ND1 1 ATOM 7969 C CD2 . HIS A 1 1001 ? 66.827 44.134 -18.120 1.00 25.35 ? 1001 HIS A CD2 1 ATOM 7970 C CE1 . HIS A 1 1001 ? 65.515 42.544 -17.365 1.00 24.70 ? 1001 HIS A CE1 1 ATOM 7971 N NE2 . HIS A 1 1001 ? 66.771 42.851 -17.623 1.00 24.70 ? 1001 HIS A NE2 1 ATOM 7972 N N . LEU A 1 1002 ? 64.027 49.232 -17.494 1.00 21.45 ? 1002 LEU A N 1 ATOM 7973 C CA . LEU A 1 1002 ? 64.090 50.631 -17.929 1.00 19.24 ? 1002 LEU A CA 1 ATOM 7974 C C . LEU A 1 1002 ? 65.360 51.303 -17.400 1.00 20.83 ? 1002 LEU A C 1 ATOM 7975 O O . LEU A 1 1002 ? 65.888 52.212 -18.052 1.00 22.54 ? 1002 LEU A O 1 ATOM 7976 C CB . LEU A 1 1002 ? 62.865 51.429 -17.435 1.00 19.10 ? 1002 LEU A CB 1 ATOM 7977 C CG . LEU A 1 1002 ? 61.620 51.235 -18.275 1.00 17.66 ? 1002 LEU A CG 1 ATOM 7978 C CD1 . LEU A 1 1002 ? 60.427 51.923 -17.626 1.00 17.74 ? 1002 LEU A CD1 1 ATOM 7979 C CD2 . LEU A 1 1002 ? 61.872 51.823 -19.648 1.00 21.72 ? 1002 LEU A CD2 1 ATOM 7980 N N . LEU A 1 1003 ? 65.852 50.895 -16.224 1.00 20.53 ? 1003 LEU A N 1 ATOM 7981 C CA . LEU A 1 1003 ? 67.087 51.454 -15.696 1.00 21.58 ? 1003 LEU A CA 1 ATOM 7982 C C . LEU A 1 1003 ? 68.141 50.343 -15.816 1.00 21.43 ? 1003 LEU A C 1 ATOM 7983 O O . LEU A 1 1003 ? 67.829 49.157 -15.685 1.00 22.88 ? 1003 LEU A O 1 ATOM 7984 C CB . LEU A 1 1003 ? 66.935 51.892 -14.243 1.00 21.33 ? 1003 LEU A CB 1 ATOM 7985 C CG . LEU A 1 1003 ? 66.183 53.229 -14.135 1.00 27.23 ? 1003 LEU A CG 1 ATOM 7986 C CD1 . LEU A 1 1003 ? 65.526 53.330 -12.783 1.00 29.49 ? 1003 LEU A CD1 1 ATOM 7987 C CD2 . LEU A 1 1003 ? 67.155 54.394 -14.385 1.00 28.47 ? 1003 LEU A CD2 1 ATOM 7988 N N . PRO A 1 1004 ? 69.390 50.726 -16.070 1.00 23.02 ? 1004 PRO A N 1 ATOM 7989 C CA . PRO A 1 1004 ? 70.423 49.706 -16.211 1.00 21.70 ? 1004 PRO A CA 1 ATOM 7990 C C . PRO A 1 1004 ? 70.844 48.996 -14.933 1.00 23.48 ? 1004 PRO A C 1 ATOM 7991 O O . PRO A 1 1004 ? 70.488 49.388 -13.810 1.00 22.09 ? 1004 PRO A O 1 ATOM 7992 C CB . PRO A 1 1004 ? 71.561 50.491 -16.838 1.00 23.27 ? 1004 PRO A CB 1 ATOM 7993 C CG . PRO A 1 1004 ? 71.493 51.773 -16.117 1.00 25.11 ? 1004 PRO A CG 1 ATOM 7994 C CD . PRO A 1 1004 ? 69.985 52.079 -16.109 1.00 23.58 ? 1004 PRO A CD 1 ATOM 7995 N N . ASN A 1 1005 ? 71.616 47.932 -15.132 1.00 23.97 ? 1005 ASN A N 1 ATOM 7996 C CA . ASN A 1 1005 ? 72.151 47.150 -14.029 1.00 22.86 ? 1005 ASN A CA 1 ATOM 7997 C C . ASN A 1 1005 ? 71.087 46.591 -13.096 1.00 22.42 ? 1005 ASN A C 1 ATOM 7998 O O . ASN A 1 1005 ? 71.269 46.623 -11.895 1.00 22.78 ? 1005 ASN A O 1 ATOM 7999 C CB . ASN A 1 1005 ? 73.104 48.002 -13.214 1.00 26.18 ? 1005 ASN A CB 1 ATOM 8000 C CG . ASN A 1 1005 ? 74.275 48.499 -14.019 1.00 30.08 ? 1005 ASN A CG 1 ATOM 8001 O OD1 . ASN A 1 1005 ? 74.962 49.402 -13.588 1.00 38.17 ? 1005 ASN A OD1 1 ATOM 8002 N ND2 . ASN A 1 1005 ? 74.522 47.905 -15.167 1.00 31.56 ? 1005 ASN A ND2 1 ATOM 8003 N N . VAL A 1 1006 ? 69.991 46.085 -13.645 1.00 22.37 ? 1006 VAL A N 1 ATOM 8004 C CA . VAL A 1 1006 ? 68.962 45.502 -12.798 1.00 23.22 ? 1006 VAL A CA 1 ATOM 8005 C C . VAL A 1 1006 ? 69.538 44.223 -12.178 1.00 23.96 ? 1006 VAL A C 1 ATOM 8006 O O . VAL A 1 1006 ? 70.212 43.434 -12.847 1.00 25.65 ? 1006 VAL A O 1 ATOM 8007 C CB . VAL A 1 1006 ? 67.629 45.204 -13.587 1.00 21.84 ? 1006 VAL A CB 1 ATOM 8008 C CG1 . VAL A 1 1006 ? 67.812 44.188 -14.671 1.00 23.06 ? 1006 VAL A CG1 1 ATOM 8009 C CG2 . VAL A 1 1006 ? 66.566 44.711 -12.611 1.00 23.79 ? 1006 VAL A CG2 1 ATOM 8010 N N . ALA A 1 1007 ? 69.287 44.053 -10.892 1.00 21.91 ? 1007 ALA A N 1 ATOM 8011 C CA . ALA A 1 1007 ? 69.771 42.890 -10.147 1.00 23.47 ? 1007 ALA A CA 1 ATOM 8012 C C . ALA A 1 1007 ? 68.595 42.082 -9.629 1.00 25.16 ? 1007 ALA A C 1 ATOM 8013 O O . ALA A 1 1007 ? 68.738 40.899 -9.294 1.00 26.60 ? 1007 ALA A O 1 ATOM 8014 C CB . ALA A 1 1007 ? 70.627 43.352 -8.983 1.00 22.61 ? 1007 ALA A CB 1 ATOM 8015 N N . ARG A 1 1008 ? 67.415 42.699 -9.540 1.00 24.17 ? 1008 ARG A N 1 ATOM 8016 C CA . ARG A 1 1008 ? 66.253 41.971 -9.035 1.00 22.31 ? 1008 ARG A CA 1 ATOM 8017 C C . ARG A 1 1008 ? 64.976 42.688 -9.461 1.00 20.14 ? 1008 ARG A C 1 ATOM 8018 O O . ARG A 1 1008 ? 64.992 43.909 -9.586 1.00 20.61 ? 1008 ARG A O 1 ATOM 8019 C CB . ARG A 1 1008 ? 66.293 41.945 -7.517 1.00 23.10 ? 1008 ARG A CB 1 ATOM 8020 C CG . ARG A 1 1008 ? 65.239 41.083 -6.862 1.00 28.26 ? 1008 ARG A CG 1 ATOM 8021 C CD . ARG A 1 1008 ? 65.350 41.227 -5.337 1.00 33.48 ? 1008 ARG A CD 1 ATOM 8022 N NE . ARG A 1 1008 ? 64.590 40.212 -4.607 1.00 39.07 ? 1008 ARG A NE 1 ATOM 8023 C CZ . ARG A 1 1008 ? 64.878 38.909 -4.590 1.00 41.85 ? 1008 ARG A CZ 1 ATOM 8024 N NH1 . ARG A 1 1008 ? 65.930 38.437 -5.265 1.00 43.39 ? 1008 ARG A NH1 1 ATOM 8025 N NH2 . ARG A 1 1008 ? 64.103 38.069 -3.904 1.00 42.09 ? 1008 ARG A NH2 1 ATOM 8026 N N . CYS A 1 1009 ? 63.902 41.934 -9.683 1.00 19.14 ? 1009 CYS A N 1 ATOM 8027 C CA . CYS A 1 1009 ? 62.617 42.517 -10.068 1.00 21.04 ? 1009 CYS A CA 1 ATOM 8028 C C . CYS A 1 1009 ? 61.549 41.768 -9.269 1.00 20.17 ? 1009 CYS A C 1 ATOM 8029 O O . CYS A 1 1009 ? 61.446 40.538 -9.360 1.00 21.24 ? 1009 CYS A O 1 ATOM 8030 C CB . CYS A 1 1009 ? 62.388 42.308 -11.547 1.00 23.46 ? 1009 CYS A CB 1 ATOM 8031 S SG . CYS A 1 1009 ? 60.809 42.965 -12.197 1.00 30.60 ? 1009 CYS A SG 1 ATOM 8032 N N . GLU A 1 1010 ? 60.739 42.515 -8.515 1.00 18.51 ? 1010 GLU A N 1 ATOM 8033 C CA . GLU A 1 1010 ? 59.702 41.935 -7.711 1.00 18.74 ? 1010 GLU A CA 1 ATOM 8034 C C . GLU A 1 1010 ? 58.333 42.557 -7.994 1.00 17.52 ? 1010 GLU A C 1 ATOM 8035 O O . GLU A 1 1010 ? 58.213 43.746 -8.256 1.00 18.50 ? 1010 GLU A O 1 ATOM 8036 C CB . GLU A 1 1010 ? 60.044 42.179 -6.236 1.00 21.76 ? 1010 GLU A CB 1 ATOM 8037 C CG . GLU A 1 1010 ? 61.293 41.395 -5.794 1.00 28.43 ? 1010 GLU A CG 1 ATOM 8038 C CD . GLU A 1 1010 ? 62.029 41.997 -4.600 1.00 32.38 ? 1010 GLU A CD 1 ATOM 8039 O OE1 . GLU A 1 1010 ? 62.463 43.174 -4.650 1.00 32.24 ? 1010 GLU A OE1 1 ATOM 8040 O OE2 . GLU A 1 1010 ? 62.187 41.261 -3.598 1.00 36.50 ? 1010 GLU A OE2 1 ATOM 8041 N N . ARG A 1 1011 ? 57.304 41.743 -7.912 1.00 17.50 ? 1011 ARG A N 1 ATOM 8042 C CA . ARG A 1 1011 ? 55.941 42.272 -7.999 1.00 15.04 ? 1011 ARG A CA 1 ATOM 8043 C C . ARG A 1 1011 ? 55.615 42.618 -6.531 1.00 16.64 ? 1011 ARG A C 1 ATOM 8044 O O . ARG A 1 1011 ? 55.941 41.845 -5.612 1.00 16.60 ? 1011 ARG A O 1 ATOM 8045 C CB . ARG A 1 1011 ? 54.967 41.226 -8.506 1.00 17.00 ? 1011 ARG A CB 1 ATOM 8046 C CG . ARG A 1 1011 ? 53.605 41.890 -8.770 1.00 20.05 ? 1011 ARG A CG 1 ATOM 8047 C CD . ARG A 1 1011 ? 52.646 40.999 -9.509 1.00 24.59 ? 1011 ARG A CD 1 ATOM 8048 N NE . ARG A 1 1011 ? 52.372 39.793 -8.744 1.00 32.05 ? 1011 ARG A NE 1 ATOM 8049 C CZ . ARG A 1 1011 ? 51.470 39.718 -7.764 1.00 34.43 ? 1011 ARG A CZ 1 ATOM 8050 N NH1 . ARG A 1 1011 ? 50.748 40.791 -7.434 1.00 37.27 ? 1011 ARG A NH1 1 ATOM 8051 N NH2 . ARG A 1 1011 ? 51.286 38.567 -7.112 1.00 36.00 ? 1011 ARG A NH2 1 ATOM 8052 N N . THR A 1 1012 ? 55.011 43.780 -6.300 1.00 16.01 ? 1012 THR A N 1 ATOM 8053 C CA . THR A 1 1012 ? 54.674 44.216 -4.960 1.00 14.90 ? 1012 THR A CA 1 ATOM 8054 C C . THR A 1 1012 ? 53.229 44.683 -4.858 1.00 13.52 ? 1012 THR A C 1 ATOM 8055 O O . THR A 1 1012 ? 52.515 44.810 -5.866 1.00 14.52 ? 1012 THR A O 1 ATOM 8056 C CB . THR A 1 1012 ? 55.557 45.438 -4.526 1.00 15.90 ? 1012 THR A CB 1 ATOM 8057 O OG1 . THR A 1 1012 ? 55.216 46.580 -5.342 1.00 14.97 ? 1012 THR A OG1 1 ATOM 8058 C CG2 . THR A 1 1012 ? 57.063 45.156 -4.736 1.00 17.11 ? 1012 THR A CG2 1 ATOM 8059 N N . THR A 1 1013 ? 52.788 44.900 -3.620 1.00 13.29 ? 1013 THR A N 1 ATOM 8060 C CA . THR A 1 1013 ? 51.492 45.525 -3.430 1.00 14.30 ? 1013 THR A CA 1 ATOM 8061 C C . THR A 1 1013 ? 51.603 46.931 -4.061 1.00 13.53 ? 1013 THR A C 1 ATOM 8062 O O . THR A 1 1013 ? 52.694 47.464 -4.285 1.00 12.74 ? 1013 THR A O 1 ATOM 8063 C CB . THR A 1 1013 ? 51.186 45.666 -1.973 1.00 13.89 ? 1013 THR A CB 1 ATOM 8064 O OG1 . THR A 1 1013 ? 52.370 46.094 -1.276 1.00 14.51 ? 1013 THR A OG1 1 ATOM 8065 C CG2 . THR A 1 1013 ? 50.675 44.310 -1.426 1.00 16.27 ? 1013 THR A CG2 1 ATOM 8066 N N . LEU A 1 1014 ? 50.448 47.552 -4.314 1.00 12.70 ? 1014 LEU A N 1 ATOM 8067 C CA . LEU A 1 1014 ? 50.463 48.853 -5.016 1.00 12.30 ? 1014 LEU A CA 1 ATOM 8068 C C . LEU A 1 1014 ? 51.140 50.005 -4.311 1.00 12.30 ? 1014 LEU A C 1 ATOM 8069 O O . LEU A 1 1014 ? 51.506 51.005 -4.930 1.00 12.59 ? 1014 LEU A O 1 ATOM 8070 C CB . LEU A 1 1014 ? 49.037 49.290 -5.415 1.00 11.94 ? 1014 LEU A CB 1 ATOM 8071 C CG . LEU A 1 1014 ? 48.253 48.342 -6.318 1.00 11.60 ? 1014 LEU A CG 1 ATOM 8072 C CD1 . LEU A 1 1014 ? 46.957 49.063 -6.724 1.00 12.66 ? 1014 LEU A CD1 1 ATOM 8073 C CD2 . LEU A 1 1014 ? 49.034 47.997 -7.603 1.00 13.25 ? 1014 LEU A CD2 1 ATOM 8074 N N . THR A 1 1015 ? 51.311 49.860 -2.993 1.00 11.01 ? 1015 THR A N 1 ATOM 8075 C CA . THR A 1 1015 ? 51.971 50.831 -2.146 1.00 11.58 ? 1015 THR A CA 1 ATOM 8076 C C . THR A 1 1015 ? 53.475 50.558 -2.071 1.00 12.01 ? 1015 THR A C 1 ATOM 8077 O O . THR A 1 1015 ? 54.169 51.326 -1.418 1.00 12.48 ? 1015 THR A O 1 ATOM 8078 C CB . THR A 1 1015 ? 51.440 50.707 -0.731 1.00 12.29 ? 1015 THR A CB 1 ATOM 8079 O OG1 . THR A 1 1015 ? 51.623 49.330 -0.334 1.00 13.09 ? 1015 THR A OG1 1 ATOM 8080 C CG2 . THR A 1 1015 ? 49.941 51.078 -0.640 1.00 13.21 ? 1015 THR A CG2 1 ATOM 8081 N N . PHE A 1 1016 ? 53.941 49.497 -2.754 1.00 12.95 ? 1016 PHE A N 1 ATOM 8082 C CA . PHE A 1 1016 ? 55.347 49.028 -2.790 1.00 13.04 ? 1016 PHE A CA 1 ATOM 8083 C C . PHE A 1 1016 ? 55.836 48.494 -1.446 1.00 14.63 ? 1016 PHE A C 1 ATOM 8084 O O . PHE A 1 1016 ? 57.007 48.144 -1.324 1.00 16.64 ? 1016 PHE A O 1 ATOM 8085 C CB . PHE A 1 1016 ? 56.307 50.162 -3.229 1.00 14.29 ? 1016 PHE A CB 1 ATOM 8086 C CG . PHE A 1 1016 ? 55.954 50.784 -4.546 1.00 13.63 ? 1016 PHE A CG 1 ATOM 8087 C CD1 . PHE A 1 1016 ? 55.853 50.023 -5.709 1.00 12.64 ? 1016 PHE A CD1 1 ATOM 8088 C CD2 . PHE A 1 1016 ? 55.767 52.181 -4.615 1.00 14.33 ? 1016 PHE A CD2 1 ATOM 8089 C CE1 . PHE A 1 1016 ? 55.566 50.652 -6.941 1.00 15.68 ? 1016 PHE A CE1 1 ATOM 8090 C CE2 . PHE A 1 1016 ? 55.491 52.788 -5.834 1.00 12.85 ? 1016 PHE A CE2 1 ATOM 8091 C CZ . PHE A 1 1016 ? 55.393 52.011 -6.989 1.00 15.10 ? 1016 PHE A CZ 1 ATOM 8092 N N . LEU A 1 1017 ? 54.926 48.321 -0.478 1.00 13.68 ? 1017 LEU A N 1 ATOM 8093 C CA . LEU A 1 1017 ? 55.361 47.906 0.867 1.00 14.72 ? 1017 LEU A CA 1 ATOM 8094 C C . LEU A 1 1017 ? 55.555 46.408 1.125 1.00 15.58 ? 1017 LEU A C 1 ATOM 8095 O O . LEU A 1 1017 ? 56.211 46.041 2.110 1.00 20.11 ? 1017 LEU A O 1 ATOM 8096 C CB . LEU A 1 1017 ? 54.405 48.508 1.900 1.00 14.59 ? 1017 LEU A CB 1 ATOM 8097 C CG . LEU A 1 1017 ? 54.375 50.037 1.847 1.00 14.94 ? 1017 LEU A CG 1 ATOM 8098 C CD1 . LEU A 1 1017 ? 53.307 50.491 2.870 1.00 16.29 ? 1017 LEU A CD1 1 ATOM 8099 C CD2 . LEU A 1 1017 ? 55.713 50.643 2.192 1.00 15.76 ? 1017 LEU A CD2 1 ATOM 8100 N N . GLN A 1 1018 ? 55.024 45.556 0.267 1.00 14.39 ? 1018 GLN A N 1 ATOM 8101 C CA . GLN A 1 1018 ? 55.206 44.118 0.447 1.00 17.04 ? 1018 GLN A CA 1 ATOM 8102 C C . GLN A 1 1018 ? 55.558 43.443 -0.870 1.00 16.75 ? 1018 GLN A C 1 ATOM 8103 O O . GLN A 1 1018 ? 54.914 43.682 -1.887 1.00 18.04 ? 1018 GLN A O 1 ATOM 8104 C CB . GLN A 1 1018 ? 53.945 43.458 1.032 1.00 18.85 ? 1018 GLN A CB 1 ATOM 8105 C CG . GLN A 1 1018 ? 54.143 41.944 1.205 1.00 23.09 ? 1018 GLN A CG 1 ATOM 8106 C CD . GLN A 1 1018 ? 52.877 41.169 1.592 1.00 28.34 ? 1018 GLN A CD 1 ATOM 8107 O OE1 . GLN A 1 1018 ? 52.949 39.950 1.856 1.00 32.84 ? 1018 GLN A OE1 1 ATOM 8108 N NE2 . GLN A 1 1018 ? 51.730 41.838 1.610 1.00 25.80 ? 1018 GLN A NE2 1 ATOM 8109 N N . ASN A 1 1019 ? 56.579 42.583 -0.838 1.00 16.25 ? 1019 ASN A N 1 ATOM 8110 C CA . ASN A 1 1019 ? 57.004 41.842 -2.017 1.00 19.14 ? 1019 ASN A CA 1 ATOM 8111 C C . ASN A 1 1019 ? 56.118 40.637 -2.144 1.00 21.13 ? 1019 ASN A C 1 ATOM 8112 O O . ASN A 1 1019 ? 55.984 39.845 -1.187 1.00 23.28 ? 1019 ASN A O 1 ATOM 8113 C CB . ASN A 1 1019 ? 58.473 41.402 -1.909 1.00 20.08 ? 1019 ASN A CB 1 ATOM 8114 C CG . ASN A 1 1019 ? 59.422 42.591 -1.773 1.00 25.39 ? 1019 ASN A CG 1 ATOM 8115 O OD1 . ASN A 1 1019 ? 59.216 43.624 -2.401 1.00 25.73 ? 1019 ASN A OD1 1 ATOM 8116 N ND2 . ASN A 1 1019 ? 60.477 42.449 -0.948 1.00 25.84 ? 1019 ASN A ND2 1 ATOM 8117 N N . LEU A 1 1020 ? 55.492 40.487 -3.298 1.00 19.94 ? 1020 LEU A N 1 ATOM 8118 C CA . LEU A 1 1020 ? 54.580 39.394 -3.549 1.00 21.06 ? 1020 LEU A CA 1 ATOM 8119 C C . LEU A 1 1020 ? 55.148 38.298 -4.446 1.00 22.92 ? 1020 LEU A C 1 ATOM 8120 O O . LEU A 1 1020 ? 54.701 37.140 -4.375 1.00 25.65 ? 1020 LEU A O 1 ATOM 8121 C CB . LEU A 1 1020 ? 53.308 39.911 -4.209 1.00 20.82 ? 1020 LEU A CB 1 ATOM 8122 C CG . LEU A 1 1020 ? 52.527 41.002 -3.479 1.00 21.31 ? 1020 LEU A CG 1 ATOM 8123 C CD1 . LEU A 1 1020 ? 51.376 41.427 -4.398 1.00 23.46 ? 1020 LEU A CD1 1 ATOM 8124 C CD2 . LEU A 1 1020 ? 52.003 40.503 -2.121 1.00 23.85 ? 1020 LEU A CD2 1 ATOM 8125 N N . GLU A 1 1021 ? 56.100 38.647 -5.302 1.00 23.88 ? 1021 GLU A N 1 ATOM 8126 C CA . GLU A 1 1021 ? 56.661 37.662 -6.236 1.00 26.67 ? 1021 GLU A CA 1 ATOM 8127 C C . GLU A 1 1021 ? 58.038 38.060 -6.737 1.00 26.32 ? 1021 GLU A C 1 ATOM 8128 O O . GLU A 1 1021 ? 58.271 39.203 -7.118 1.00 24.51 ? 1021 GLU A O 1 ATOM 8129 C CB . GLU A 1 1021 ? 55.697 37.523 -7.415 1.00 28.85 ? 1021 GLU A CB 1 ATOM 8130 C CG . GLU A 1 1021 ? 56.054 36.516 -8.471 1.00 37.66 ? 1021 GLU A CG 1 ATOM 8131 C CD . GLU A 1 1021 ? 55.057 36.552 -9.616 1.00 39.87 ? 1021 GLU A CD 1 ATOM 8132 O OE1 . GLU A 1 1021 ? 54.065 37.330 -9.531 1.00 42.00 ? 1021 GLU A OE1 1 ATOM 8133 O OE2 . GLU A 1 1021 ? 55.279 35.811 -10.605 1.00 44.91 ? 1021 GLU A OE2 1 ATOM 8134 N N . HIS A 1 1022 ? 58.968 37.104 -6.735 1.00 26.60 ? 1022 HIS A N 1 ATOM 8135 C CA . HIS A 1 1022 ? 60.319 37.348 -7.204 1.00 27.63 ? 1022 HIS A CA 1 ATOM 8136 C C . HIS A 1 1022 ? 60.241 36.958 -8.667 1.00 29.20 ? 1022 HIS A C 1 ATOM 8137 O O . HIS A 1 1022 ? 59.898 35.828 -9.005 1.00 29.55 ? 1022 HIS A O 1 ATOM 8138 C CB . HIS A 1 1022 ? 61.295 36.462 -6.428 1.00 30.12 ? 1022 HIS A CB 1 ATOM 8139 C CG . HIS A 1 1022 ? 62.724 36.725 -6.755 1.00 35.02 ? 1022 HIS A CG 1 ATOM 8140 N ND1 . HIS A 1 1022 ? 63.696 35.750 -6.664 1.00 38.30 ? 1022 HIS A ND1 1 ATOM 8141 C CD2 . HIS A 1 1022 ? 63.347 37.843 -7.203 1.00 37.17 ? 1022 HIS A CD2 1 ATOM 8142 C CE1 . HIS A 1 1022 ? 64.856 36.254 -7.048 1.00 38.76 ? 1022 HIS A CE1 1 ATOM 8143 N NE2 . HIS A 1 1022 ? 64.673 37.522 -7.380 1.00 39.73 ? 1022 HIS A NE2 1 ATOM 8144 N N . LEU A 1 1023 ? 60.552 37.886 -9.557 1.00 27.45 ? 1023 LEU A N 1 ATOM 8145 C CA . LEU A 1 1023 ? 60.360 37.595 -10.959 1.00 28.72 ? 1023 LEU A CA 1 ATOM 8146 C C . LEU A 1 1023 ? 61.534 37.032 -11.726 1.00 29.17 ? 1023 LEU A C 1 ATOM 8147 O O . LEU A 1 1023 ? 62.636 37.580 -11.706 1.00 28.68 ? 1023 LEU A O 1 ATOM 8148 C CB . LEU A 1 1023 ? 59.835 38.853 -11.654 1.00 27.86 ? 1023 LEU A CB 1 ATOM 8149 C CG . LEU A 1 1023 ? 58.493 39.332 -11.086 1.00 28.09 ? 1023 LEU A CG 1 ATOM 8150 C CD1 . LEU A 1 1023 ? 58.361 40.816 -11.251 1.00 30.94 ? 1023 LEU A CD1 1 ATOM 8151 C CD2 . LEU A 1 1023 ? 57.352 38.572 -11.761 1.00 31.10 ? 1023 LEU A CD2 1 ATOM 8152 N N . ASP A 1 1024 ? 61.264 35.936 -12.423 1.00 33.51 ? 1024 ASP A N 1 ATOM 8153 C CA . ASP A 1 1024 ? 62.283 35.274 -13.229 1.00 36.00 ? 1024 ASP A CA 1 ATOM 8154 C C . ASP A 1 1024 ? 62.829 36.136 -14.341 1.00 35.15 ? 1024 ASP A C 1 ATOM 8155 O O . ASP A 1 1024 ? 62.083 36.827 -15.067 1.00 36.14 ? 1024 ASP A O 1 ATOM 8156 C CB . ASP A 1 1024 ? 61.727 34.004 -13.847 1.00 40.99 ? 1024 ASP A CB 1 ATOM 8157 C CG . ASP A 1 1024 ? 61.290 33.020 -12.812 1.00 45.99 ? 1024 ASP A CG 1 ATOM 8158 O OD1 . ASP A 1 1024 ? 62.009 32.915 -11.780 1.00 49.59 ? 1024 ASP A OD1 1 ATOM 8159 O OD2 . ASP A 1 1024 ? 60.242 32.355 -13.034 1.00 48.50 ? 1024 ASP A OD2 1 ATOM 8160 N N . GLY A 1 1025 ? 64.141 36.077 -14.475 1.00 32.53 ? 1025 GLY A N 1 ATOM 8161 C CA . GLY A 1 1025 ? 64.803 36.821 -15.516 1.00 31.65 ? 1025 GLY A CA 1 ATOM 8162 C C . GLY A 1 1025 ? 64.714 38.303 -15.280 1.00 29.77 ? 1025 GLY A C 1 ATOM 8163 O O . GLY A 1 1025 ? 65.087 39.081 -16.148 1.00 30.57 ? 1025 GLY A O 1 ATOM 8164 N N . MET A 1 1026 ? 64.209 38.689 -14.111 1.00 28.27 ? 1026 MET A N 1 ATOM 8165 C CA . MET A 1 1026 ? 64.092 40.103 -13.775 1.00 28.38 ? 1026 MET A CA 1 ATOM 8166 C C . MET A 1 1026 ? 63.200 40.815 -14.778 1.00 26.05 ? 1026 MET A C 1 ATOM 8167 O O . MET A 1 1026 ? 63.422 41.976 -15.106 1.00 25.46 ? 1026 MET A O 1 ATOM 8168 C CB . MET A 1 1026 ? 65.475 40.761 -13.731 1.00 27.71 ? 1026 MET A CB 1 ATOM 8169 C CG . MET A 1 1026 ? 66.445 40.061 -12.758 1.00 31.64 ? 1026 MET A CG 1 ATOM 8170 S SD . MET A 1 1026 ? 68.051 40.863 -12.673 1.00 33.87 ? 1026 MET A SD 1 ATOM 8171 C CE . MET A 1 1026 ? 68.714 40.490 -14.323 1.00 34.82 ? 1026 MET A CE 1 ATOM 8172 N N . VAL A 1 1027 ? 62.189 40.116 -15.269 1.00 24.86 ? 1027 VAL A N 1 ATOM 8173 C CA . VAL A 1 1027 ? 61.286 40.702 -16.239 1.00 25.64 ? 1027 VAL A CA 1 ATOM 8174 C C . VAL A 1 1027 ? 59.919 40.930 -15.592 1.00 28.06 ? 1027 VAL A C 1 ATOM 8175 O O . VAL A 1 1027 ? 59.342 40.029 -14.974 1.00 27.68 ? 1027 VAL A O 1 ATOM 8176 C CB . VAL A 1 1027 ? 61.123 39.796 -17.470 1.00 25.85 ? 1027 VAL A CB 1 ATOM 8177 C CG1 . VAL A 1 1027 ? 60.043 40.351 -18.397 1.00 27.36 ? 1027 VAL A CG1 1 ATOM 8178 C CG2 . VAL A 1 1027 ? 62.443 39.721 -18.242 1.00 28.25 ? 1027 VAL A CG2 1 ATOM 8179 N N . ALA A 1 1028 ? 59.405 42.145 -15.721 1.00 28.79 ? 1028 ALA A N 1 ATOM 8180 C CA . ALA A 1 1028 ? 58.091 42.471 -15.159 1.00 29.72 ? 1028 ALA A CA 1 ATOM 8181 C C . ALA A 1 1028 ? 57.095 42.242 -16.274 1.00 30.88 ? 1028 ALA A C 1 ATOM 8182 O O . ALA A 1 1028 ? 57.124 42.955 -17.277 1.00 32.35 ? 1028 ALA A O 1 ATOM 8183 C CB . ALA A 1 1028 ? 58.052 43.937 -14.733 1.00 29.68 ? 1028 ALA A CB 1 ATOM 8184 N N . PRO A 1 1029 ? 56.212 41.246 -16.129 1.00 29.42 ? 1029 PRO A N 1 ATOM 8185 C CA . PRO A 1 1029 ? 55.235 41.007 -17.196 1.00 31.23 ? 1029 PRO A CA 1 ATOM 8186 C C . PRO A 1 1029 ? 54.153 42.083 -17.268 1.00 29.78 ? 1029 PRO A C 1 ATOM 8187 O O . PRO A 1 1029 ? 53.863 42.734 -16.280 1.00 33.18 ? 1029 PRO A O 1 ATOM 8188 C CB . PRO A 1 1029 ? 54.658 39.638 -16.856 1.00 30.95 ? 1029 PRO A CB 1 ATOM 8189 C CG . PRO A 1 1029 ? 54.914 39.466 -15.397 1.00 31.20 ? 1029 PRO A CG 1 ATOM 8190 C CD . PRO A 1 1029 ? 56.188 40.192 -15.102 1.00 29.43 ? 1029 PRO A CD 1 ATOM 8191 N N . GLU A 1 1030 ? 53.576 42.288 -18.441 1.00 30.35 ? 1030 GLU A N 1 ATOM 8192 C CA . GLU A 1 1030 ? 52.509 43.270 -18.555 1.00 30.58 ? 1030 GLU A CA 1 ATOM 8193 C C . GLU A 1 1030 ? 51.239 42.697 -17.912 1.00 30.27 ? 1030 GLU A C 1 ATOM 8194 O O . GLU A 1 1030 ? 51.047 41.469 -17.794 1.00 33.16 ? 1030 GLU A O 1 ATOM 8195 C CB . GLU A 1 1030 ? 52.254 43.635 -20.029 1.00 30.83 ? 1030 GLU A CB 1 ATOM 8196 C CG . GLU A 1 1030 ? 53.432 44.355 -20.717 1.00 29.20 ? 1030 GLU A CG 1 ATOM 8197 C CD . GLU A 1 1030 ? 53.099 44.765 -22.141 1.00 31.77 ? 1030 GLU A CD 1 ATOM 8198 O OE1 . GLU A 1 1030 ? 52.063 44.283 -22.654 1.00 33.63 ? 1030 GLU A OE1 1 ATOM 8199 O OE2 . GLU A 1 1030 ? 53.870 45.551 -22.753 1.00 27.04 ? 1030 GLU A OE2 1 ATOM 8200 N N . VAL A 1 1031 ? 50.369 43.595 -17.507 1.00 28.96 ? 1031 VAL A N 1 ATOM 8201 C CA . VAL A 1 1031 ? 49.142 43.207 -16.836 1.00 24.05 ? 1031 VAL A CA 1 ATOM 8202 C C . VAL A 1 1031 ? 47.956 42.985 -17.781 1.00 22.17 ? 1031 VAL A C 1 ATOM 8203 O O . VAL A 1 1031 ? 48.014 43.335 -18.949 1.00 22.49 ? 1031 VAL A O 1 ATOM 8204 C CB . VAL A 1 1031 ? 48.775 44.277 -15.781 1.00 27.11 ? 1031 VAL A CB 1 ATOM 8205 C CG1 . VAL A 1 1031 ? 49.976 44.499 -14.855 1.00 29.31 ? 1031 VAL A CG1 1 ATOM 8206 C CG2 . VAL A 1 1031 ? 48.367 45.546 -16.451 1.00 26.10 ? 1031 VAL A CG2 1 ATOM 8207 N N . CYS A 1 1032 ? 46.914 42.351 -17.256 1.00 19.11 ? 1032 CYS A N 1 ATOM 8208 C CA . CYS A 1 1032 ? 45.674 42.066 -17.972 1.00 18.66 ? 1032 CYS A CA 1 ATOM 8209 C C . CYS A 1 1032 ? 44.756 43.288 -18.051 1.00 17.06 ? 1032 CYS A C 1 ATOM 8210 O O . CYS A 1 1032 ? 44.913 44.209 -17.282 1.00 16.72 ? 1032 CYS A O 1 ATOM 8211 C CB . CYS A 1 1032 ? 44.909 40.989 -17.244 1.00 17.03 ? 1032 CYS A CB 1 ATOM 8212 S SG . CYS A 1 1032 ? 45.735 39.358 -17.399 1.00 27.38 ? 1032 CYS A SG 1 ATOM 8213 N N . PRO A 1 1033 ? 43.818 43.323 -19.022 1.00 16.38 ? 1033 PRO A N 1 ATOM 8214 C CA . PRO A 1 1033 ? 42.907 44.468 -19.103 1.00 16.31 ? 1033 PRO A CA 1 ATOM 8215 C C . PRO A 1 1033 ? 42.179 44.629 -17.773 1.00 15.04 ? 1033 PRO A C 1 ATOM 8216 O O . PRO A 1 1033 ? 41.680 43.677 -17.167 1.00 15.37 ? 1033 PRO A O 1 ATOM 8217 C CB . PRO A 1 1033 ? 41.910 44.062 -20.216 1.00 16.63 ? 1033 PRO A CB 1 ATOM 8218 C CG . PRO A 1 1033 ? 42.733 43.122 -21.055 1.00 16.82 ? 1033 PRO A CG 1 ATOM 8219 C CD . PRO A 1 1033 ? 43.538 42.330 -20.089 1.00 18.37 ? 1033 PRO A CD 1 ATOM 8220 N N . MET A 1 1034 ? 42.087 45.882 -17.361 1.00 13.82 ? 1034 MET A N 1 ATOM 8221 C CA . MET A 1 1034 ? 41.477 46.332 -16.096 1.00 14.33 ? 1034 MET A CA 1 ATOM 8222 C C . MET A 1 1034 ? 42.284 45.971 -14.852 1.00 18.16 ? 1034 MET A C 1 ATOM 8223 O O . MET A 1 1034 ? 41.803 46.210 -13.731 1.00 21.78 ? 1034 MET A O 1 ATOM 8224 C CB . MET A 1 1034 ? 40.025 45.850 -15.916 1.00 14.66 ? 1034 MET A CB 1 ATOM 8225 C CG . MET A 1 1034 ? 39.093 46.360 -17.025 1.00 15.52 ? 1034 MET A CG 1 ATOM 8226 S SD . MET A 1 1034 ? 39.147 48.210 -17.261 1.00 17.03 ? 1034 MET A SD 1 ATOM 8227 C CE . MET A 1 1034 ? 38.356 48.775 -15.660 1.00 16.62 ? 1034 MET A CE 1 ATOM 8228 N N . GLU A 1 1035 ? 43.494 45.475 -15.033 1.00 14.67 ? 1035 GLU A N 1 ATOM 8229 C CA . GLU A 1 1035 ? 44.312 45.135 -13.875 1.00 14.72 ? 1035 GLU A CA 1 ATOM 8230 C C . GLU A 1 1035 ? 45.362 46.215 -13.658 1.00 14.54 ? 1035 GLU A C 1 ATOM 8231 O O . GLU A 1 1035 ? 45.708 46.962 -14.553 1.00 14.78 ? 1035 GLU A O 1 ATOM 8232 C CB . GLU A 1 1035 ? 44.938 43.748 -14.050 1.00 20.54 ? 1035 GLU A CB 1 ATOM 8233 C CG . GLU A 1 1035 ? 43.883 42.647 -13.841 1.00 29.76 ? 1035 GLU A CG 1 ATOM 8234 C CD . GLU A 1 1035 ? 43.412 42.543 -12.379 1.00 35.79 ? 1035 GLU A CD 1 ATOM 8235 O OE1 . GLU A 1 1035 ? 42.606 43.395 -11.918 1.00 36.87 ? 1035 GLU A OE1 1 ATOM 8236 O OE2 . GLU A 1 1035 ? 43.872 41.598 -11.691 1.00 42.18 ? 1035 GLU A OE2 1 ATOM 8237 N N . THR A 1 1036 ? 45.867 46.292 -12.426 1.00 14.73 ? 1036 THR A N 1 ATOM 8238 C CA . THR A 1 1036 ? 46.881 47.251 -12.020 1.00 14.95 ? 1036 THR A CA 1 ATOM 8239 C C . THR A 1 1036 ? 47.840 46.423 -11.186 1.00 15.73 ? 1036 THR A C 1 ATOM 8240 O O . THR A 1 1036 ? 47.408 45.662 -10.318 1.00 17.11 ? 1036 THR A O 1 ATOM 8241 C CB . THR A 1 1036 ? 46.273 48.359 -11.136 1.00 15.51 ? 1036 THR A CB 1 ATOM 8242 O OG1 . THR A 1 1036 ? 45.198 48.986 -11.832 1.00 15.03 ? 1036 THR A OG1 1 ATOM 8243 C CG2 . THR A 1 1036 ? 47.332 49.415 -10.768 1.00 15.45 ? 1036 THR A CG2 1 ATOM 8244 N N . ALA A 1 1037 ? 49.129 46.527 -11.501 1.00 14.75 ? 1037 ALA A N 1 ATOM 8245 C CA . ALA A 1 1037 ? 50.153 45.801 -10.754 1.00 14.62 ? 1037 ALA A CA 1 ATOM 8246 C C . ALA A 1 1037 ? 51.279 46.748 -10.429 1.00 14.92 ? 1037 ALA A C 1 ATOM 8247 O O . ALA A 1 1037 ? 51.436 47.797 -11.079 1.00 16.39 ? 1037 ALA A O 1 ATOM 8248 C CB . ALA A 1 1037 ? 50.694 44.631 -11.602 1.00 18.43 ? 1037 ALA A CB 1 ATOM 8249 N N . ALA A 1 1038 ? 52.066 46.415 -9.414 1.00 12.63 ? 1038 ALA A N 1 ATOM 8250 C CA . ALA A 1 1038 ? 53.202 47.221 -9.054 1.00 14.96 ? 1038 ALA A CA 1 ATOM 8251 C C . ALA A 1 1038 ? 54.463 46.358 -9.080 1.00 14.75 ? 1038 ALA A C 1 ATOM 8252 O O . ALA A 1 1038 ? 54.426 45.190 -8.749 1.00 14.66 ? 1038 ALA A O 1 ATOM 8253 C CB . ALA A 1 1038 ? 53.015 47.840 -7.670 1.00 14.18 ? 1038 ALA A CB 1 ATOM 8254 N N . TYR A 1 1039 ? 55.549 46.962 -9.520 1.00 15.28 ? 1039 TYR A N 1 ATOM 8255 C CA . TYR A 1 1039 ? 56.833 46.282 -9.592 1.00 15.45 ? 1039 TYR A CA 1 ATOM 8256 C C . TYR A 1 1039 ? 57.911 47.157 -9.052 1.00 17.05 ? 1039 TYR A C 1 ATOM 8257 O O . TYR A 1 1039 ? 57.836 48.368 -9.171 1.00 18.95 ? 1039 TYR A O 1 ATOM 8258 C CB . TYR A 1 1039 ? 57.190 45.949 -11.036 1.00 15.98 ? 1039 TYR A CB 1 ATOM 8259 C CG . TYR A 1 1039 ? 56.198 45.063 -11.718 1.00 17.06 ? 1039 TYR A CG 1 ATOM 8260 C CD1 . TYR A 1 1039 ? 56.171 43.686 -11.484 1.00 19.53 ? 1039 TYR A CD1 1 ATOM 8261 C CD2 . TYR A 1 1039 ? 55.268 45.599 -12.600 1.00 18.93 ? 1039 TYR A CD2 1 ATOM 8262 C CE1 . TYR A 1 1039 ? 55.242 42.872 -12.113 1.00 20.00 ? 1039 TYR A CE1 1 ATOM 8263 C CE2 . TYR A 1 1039 ? 54.337 44.804 -13.247 1.00 20.76 ? 1039 TYR A CE2 1 ATOM 8264 C CZ . TYR A 1 1039 ? 54.325 43.452 -13.011 1.00 21.40 ? 1039 TYR A CZ 1 ATOM 8265 O OH . TYR A 1 1039 ? 53.427 42.685 -13.724 1.00 27.07 ? 1039 TYR A OH 1 ATOM 8266 N N . VAL A 1 1040 ? 58.914 46.543 -8.426 1.00 16.56 ? 1040 VAL A N 1 ATOM 8267 C CA . VAL A 1 1040 ? 60.057 47.280 -7.932 1.00 17.33 ? 1040 VAL A CA 1 ATOM 8268 C C . VAL A 1 1040 ? 61.287 46.627 -8.544 1.00 17.96 ? 1040 VAL A C 1 ATOM 8269 O O . VAL A 1 1040 ? 61.498 45.409 -8.409 1.00 17.91 ? 1040 VAL A O 1 ATOM 8270 C CB . VAL A 1 1040 ? 60.178 47.232 -6.420 1.00 16.28 ? 1040 VAL A CB 1 ATOM 8271 C CG1 . VAL A 1 1040 ? 61.502 47.900 -5.983 1.00 17.70 ? 1040 VAL A CG1 1 ATOM 8272 C CG2 . VAL A 1 1040 ? 58.998 48.013 -5.792 1.00 17.11 ? 1040 VAL A CG2 1 ATOM 8273 N N . SER A 1 1041 ? 62.099 47.437 -9.223 1.00 16.46 ? 1041 SER A N 1 ATOM 8274 C CA . SER A 1 1041 ? 63.340 46.938 -9.778 1.00 16.30 ? 1041 SER A CA 1 ATOM 8275 C C . SER A 1 1041 ? 64.475 47.397 -8.854 1.00 16.00 ? 1041 SER A C 1 ATOM 8276 O O . SER A 1 1041 ? 64.478 48.537 -8.332 1.00 16.32 ? 1041 SER A O 1 ATOM 8277 C CB . SER A 1 1041 ? 63.564 47.445 -11.197 1.00 16.69 ? 1041 SER A CB 1 ATOM 8278 O OG . SER A 1 1041 ? 63.636 48.834 -11.265 1.00 18.17 ? 1041 SER A OG 1 ATOM 8279 N N . SER A 1 1042 ? 65.436 46.485 -8.634 1.00 17.99 ? 1042 SER A N 1 ATOM 8280 C CA . SER A 1 1042 ? 66.602 46.765 -7.792 1.00 17.05 ? 1042 SER A CA 1 ATOM 8281 C C . SER A 1 1042 ? 67.844 46.839 -8.697 1.00 17.13 ? 1042 SER A C 1 ATOM 8282 O O . SER A 1 1042 ? 67.977 46.017 -9.611 1.00 20.83 ? 1042 SER A O 1 ATOM 8283 C CB . SER A 1 1042 ? 66.778 45.653 -6.749 1.00 18.27 ? 1042 SER A CB 1 ATOM 8284 O OG . SER A 1 1042 ? 65.708 45.679 -5.804 1.00 19.86 ? 1042 SER A OG 1 ATOM 8285 N N . HIS A 1 1043 ? 68.705 47.812 -8.432 1.00 19.00 ? 1043 HIS A N 1 ATOM 8286 C CA . HIS A 1 1043 ? 69.884 48.079 -9.272 1.00 17.76 ? 1043 HIS A CA 1 ATOM 8287 C C . HIS A 1 1043 ? 71.149 48.189 -8.435 1.00 22.30 ? 1043 HIS A C 1 ATOM 8288 O O . HIS A 1 1043 ? 71.184 48.861 -7.404 1.00 21.38 ? 1043 HIS A O 1 ATOM 8289 C CB . HIS A 1 1043 ? 69.641 49.371 -10.066 1.00 19.48 ? 1043 HIS A CB 1 ATOM 8290 C CG . HIS A 1 1043 ? 68.340 49.353 -10.809 1.00 20.30 ? 1043 HIS A CG 1 ATOM 8291 N ND1 . HIS A 1 1043 ? 68.227 48.868 -12.095 1.00 19.71 ? 1043 HIS A ND1 1 ATOM 8292 C CD2 . HIS A 1 1043 ? 67.074 49.614 -10.391 1.00 17.04 ? 1043 HIS A CD2 1 ATOM 8293 C CE1 . HIS A 1 1043 ? 66.948 48.834 -12.439 1.00 19.50 ? 1043 HIS A CE1 1 ATOM 8294 N NE2 . HIS A 1 1043 ? 66.230 49.278 -11.414 1.00 17.62 ? 1043 HIS A NE2 1 ATOM 8295 N N . SER A 1 1044 ? 72.183 47.495 -8.916 1.00 26.43 ? 1044 SER A N 1 ATOM 8296 C CA . SER A 1 1044 ? 73.461 47.460 -8.216 1.00 33.10 ? 1044 SER A CA 1 ATOM 8297 C C . SER A 1 1044 ? 74.380 48.562 -8.716 1.00 34.92 ? 1044 SER A C 1 ATOM 8298 O O . SER A 1 1044 ? 75.376 48.900 -8.086 1.00 37.81 ? 1044 SER A O 1 ATOM 8299 C CB . SER A 1 1044 ? 74.117 46.096 -8.448 1.00 33.46 ? 1044 SER A CB 1 ATOM 8300 O OG . SER A 1 1044 ? 74.118 45.760 -9.838 1.00 36.01 ? 1044 SER A OG 1 ATOM 8301 N N . SER A 1 1045 ? 73.950 49.092 -9.850 1.00 38.70 ? 1045 SER A N 1 ATOM 8302 C CA . SER A 1 1045 ? 74.537 50.117 -10.707 1.00 43.20 ? 1045 SER A CA 1 ATOM 8303 C C . SER A 1 1045 ? 76.071 50.286 -10.851 1.00 44.01 ? 1045 SER A C 1 ATOM 8304 O O . SER A 1 1045 ? 76.886 49.416 -10.427 1.00 46.45 ? 1045 SER A O 1 ATOM 8305 C CB . SER A 1 1045 ? 73.832 51.460 -10.438 1.00 43.20 ? 1045 SER A CB 1 ATOM 8306 O OG . SER A 1 1045 ? 74.165 52.448 -11.395 1.00 42.97 ? 1045 SER A OG 1 ATOM 8307 O OXT . SER A 1 1045 ? 76.470 51.320 -11.475 1.00 48.74 ? 1045 SER A OXT 1 HETATM 8308 C C1 . NAG B 2 . ? 58.378 44.812 12.817 1.00 40.75 ? 1802 NAG A C1 1 HETATM 8309 C C2 . NAG B 2 . ? 59.503 44.462 13.796 1.00 44.46 ? 1802 NAG A C2 1 HETATM 8310 C C3 . NAG B 2 . ? 60.007 43.031 13.602 1.00 46.95 ? 1802 NAG A C3 1 HETATM 8311 C C4 . NAG B 2 . ? 58.837 42.063 13.642 1.00 47.82 ? 1802 NAG A C4 1 HETATM 8312 C C5 . NAG B 2 . ? 57.794 42.480 12.601 1.00 48.35 ? 1802 NAG A C5 1 HETATM 8313 C C6 . NAG B 2 . ? 56.581 41.566 12.622 1.00 49.79 ? 1802 NAG A C6 1 HETATM 8314 C C7 . NAG B 2 . ? 60.915 46.211 14.624 1.00 49.31 ? 1802 NAG A C7 1 HETATM 8315 C C8 . NAG B 2 . ? 61.932 45.702 15.634 1.00 51.27 ? 1802 NAG A C8 1 HETATM 8316 N N2 . NAG B 2 . ? 60.596 45.398 13.622 1.00 47.01 ? 1802 NAG A N2 1 HETATM 8317 O O3 . NAG B 2 . ? 60.917 42.713 14.649 1.00 47.77 ? 1802 NAG A O3 1 HETATM 8318 O O4 . NAG B 2 . ? 59.304 40.746 13.372 1.00 50.33 ? 1802 NAG A O4 1 HETATM 8319 O O5 . NAG B 2 . ? 57.328 43.831 12.874 1.00 45.01 ? 1802 NAG A O5 1 HETATM 8320 O O6 . NAG B 2 . ? 56.921 40.252 12.183 1.00 54.76 ? 1802 NAG A O6 1 HETATM 8321 O O7 . NAG B 2 . ? 60.413 47.328 14.768 1.00 52.16 ? 1802 NAG A O7 1 HETATM 8322 P P . PO4 C 3 . ? 45.255 65.328 -29.614 1.00 32.06 ? 1803 PO4 A P 1 HETATM 8323 O O1 . PO4 C 3 . ? 44.753 66.671 -30.271 1.00 37.51 ? 1803 PO4 A O1 1 HETATM 8324 O O2 . PO4 C 3 . ? 46.657 64.906 -30.026 1.00 36.56 ? 1803 PO4 A O2 1 HETATM 8325 O O3 . PO4 C 3 . ? 44.193 64.234 -29.989 1.00 38.52 ? 1803 PO4 A O3 1 HETATM 8326 O O4 . PO4 C 3 . ? 45.217 65.562 -28.097 1.00 38.02 ? 1803 PO4 A O4 1 HETATM 8327 ZN ZN . ZN D 4 . ? 34.480 63.960 7.933 1.00 13.25 ? 1805 ZN A ZN 1 HETATM 8328 C C8 . GB2 E 5 . ? 29.014 65.265 12.129 1.00 30.03 ? 1804 GB2 A C8 1 HETATM 8329 N N7 . GB2 E 5 . ? 29.894 65.067 10.978 1.00 27.70 ? 1804 GB2 A N7 1 HETATM 8330 C C6 . GB2 E 5 . ? 29.808 65.758 9.700 1.00 22.48 ? 1804 GB2 A C6 1 HETATM 8331 C C5 . GB2 E 5 . ? 30.957 65.230 8.842 1.00 17.95 ? 1804 GB2 A C5 1 HETATM 8332 N N1 . GB2 E 5 . ? 30.755 65.365 7.415 1.00 16.62 ? 1804 GB2 A N1 1 HETATM 8333 C C2 . GB2 E 5 . ? 31.326 66.569 6.813 1.00 18.00 ? 1804 GB2 A C2 1 HETATM 8334 C C3 . GB2 E 5 . ? 32.651 66.527 7.575 1.00 16.61 ? 1804 GB2 A C3 1 HETATM 8335 O O3 . GB2 E 5 . ? 33.681 65.767 6.967 1.00 16.03 ? 1804 GB2 A O3 1 HETATM 8336 C C4 . GB2 E 5 . ? 32.254 66.020 8.976 1.00 17.26 ? 1804 GB2 A C4 1 HETATM 8337 O O4 . GB2 E 5 . ? 33.208 65.124 9.529 1.00 14.94 ? 1804 GB2 A O4 1 HETATM 8338 C C15 . GB2 E 5 . ? 27.382 67.327 11.668 1.00 31.87 ? 1804 GB2 A C15 1 HETATM 8339 C C14 . GB2 E 5 . ? 27.073 68.715 11.823 1.00 34.62 ? 1804 GB2 A C14 1 HETATM 8340 C C13 . GB2 E 5 . ? 27.924 69.560 12.572 1.00 31.55 ? 1804 GB2 A C13 1 HETATM 8341 C C12 . GB2 E 5 . ? 29.064 68.969 13.140 1.00 32.41 ? 1804 GB2 A C12 1 HETATM 8342 C C11 . GB2 E 5 . ? 29.417 67.596 13.017 1.00 32.20 ? 1804 GB2 A C11 1 HETATM 8343 C C10 . GB2 E 5 . ? 28.556 66.736 12.259 1.00 32.23 ? 1804 GB2 A C10 1 HETATM 8344 C C9 . GB2 E 5 . ? 27.851 64.285 12.003 1.00 33.01 ? 1804 GB2 A C9 1 HETATM 8345 O O9 . GB2 E 5 . ? 28.327 63.103 11.363 1.00 33.67 ? 1804 GB2 A O9 1 HETATM 8346 C C1 . MPD F 6 . ? 14.724 60.812 10.260 1.00 22.58 ? 1801 MPD A C1 1 HETATM 8347 C C2 . MPD F 6 . ? 16.150 60.912 10.629 1.00 24.40 ? 1801 MPD A C2 1 HETATM 8348 O O2 . MPD F 6 . ? 16.891 59.953 9.787 1.00 26.53 ? 1801 MPD A O2 1 HETATM 8349 C CM . MPD F 6 . ? 16.677 62.304 10.317 1.00 27.54 ? 1801 MPD A CM 1 HETATM 8350 C C3 . MPD F 6 . ? 16.279 60.553 12.140 1.00 24.99 ? 1801 MPD A C3 1 HETATM 8351 C C4 . MPD F 6 . ? 17.662 60.411 12.782 1.00 22.23 ? 1801 MPD A C4 1 HETATM 8352 O O4 . MPD F 6 . ? 17.588 59.483 13.878 1.00 19.30 ? 1801 MPD A O4 1 HETATM 8353 C C5 . MPD F 6 . ? 18.120 61.751 13.378 1.00 24.37 ? 1801 MPD A C5 1 HETATM 8354 O O . HOH G 7 . ? 27.976 46.752 -31.343 1.00 31.91 ? 1806 HOH A O 1 HETATM 8355 O O . HOH G 7 . ? 28.287 44.047 -29.444 1.00 39.55 ? 1807 HOH A O 1 HETATM 8356 O O . HOH G 7 . ? 26.306 44.063 -27.192 1.00 37.81 ? 1808 HOH A O 1 HETATM 8357 O O . HOH G 7 . ? 26.839 41.280 -27.395 1.00 38.61 ? 1809 HOH A O 1 HETATM 8358 O O . HOH G 7 . ? 29.301 40.809 -25.461 1.00 30.27 ? 1810 HOH A O 1 HETATM 8359 O O . HOH G 7 . ? 28.540 40.977 -21.542 1.00 18.58 ? 1811 HOH A O 1 HETATM 8360 O O . HOH G 7 . ? 27.702 38.397 -22.502 1.00 36.79 ? 1812 HOH A O 1 HETATM 8361 O O . HOH G 7 . ? 27.673 36.220 -19.559 1.00 29.16 ? 1813 HOH A O 1 HETATM 8362 O O . HOH G 7 . ? 29.273 33.978 -19.310 1.00 47.18 ? 1814 HOH A O 1 HETATM 8363 O O . HOH G 7 . ? 29.492 34.752 -16.226 1.00 34.33 ? 1815 HOH A O 1 HETATM 8364 O O . HOH G 7 . ? 30.266 34.933 -12.210 1.00 25.63 ? 1816 HOH A O 1 HETATM 8365 O O . HOH G 7 . ? 30.376 34.477 -9.532 1.00 37.78 ? 1817 HOH A O 1 HETATM 8366 O O . HOH G 7 . ? 30.125 33.131 -6.028 1.00 44.26 ? 1818 HOH A O 1 HETATM 8367 O O . HOH G 7 . ? 28.073 35.076 -6.572 1.00 27.98 ? 1819 HOH A O 1 HETATM 8368 O O . HOH G 7 . ? 25.248 34.197 -6.840 1.00 42.92 ? 1820 HOH A O 1 HETATM 8369 O O . HOH G 7 . ? 22.829 36.327 -9.364 1.00 38.05 ? 1821 HOH A O 1 HETATM 8370 O O . HOH G 7 . ? 24.409 38.853 -11.390 1.00 24.64 ? 1822 HOH A O 1 HETATM 8371 O O . HOH G 7 . ? 22.200 40.429 -11.079 1.00 26.15 ? 1823 HOH A O 1 HETATM 8372 O O . HOH G 7 . ? 21.874 40.086 -8.517 1.00 26.90 ? 1824 HOH A O 1 HETATM 8373 O O . HOH G 7 . ? 20.672 42.483 -7.203 1.00 22.01 ? 1825 HOH A O 1 HETATM 8374 O O . HOH G 7 . ? 19.690 41.264 -4.934 1.00 30.19 ? 1826 HOH A O 1 HETATM 8375 O O . HOH G 7 . ? 19.110 42.214 -2.469 1.00 31.77 ? 1827 HOH A O 1 HETATM 8376 O O . HOH G 7 . ? 16.607 42.807 -2.167 1.00 30.08 ? 1828 HOH A O 1 HETATM 8377 O O . HOH G 7 . ? 18.690 39.053 -2.508 1.00 42.50 ? 1829 HOH A O 1 HETATM 8378 O O . HOH G 7 . ? 17.771 37.598 -0.005 1.00 42.33 ? 1830 HOH A O 1 HETATM 8379 O O . HOH G 7 . ? 21.947 36.636 0.357 1.00 26.57 ? 1831 HOH A O 1 HETATM 8380 O O . HOH G 7 . ? 24.408 34.211 0.380 1.00 49.90 ? 1832 HOH A O 1 HETATM 8381 O O . HOH G 7 . ? 27.044 33.479 -3.086 1.00 44.06 ? 1833 HOH A O 1 HETATM 8382 O O . HOH G 7 . ? 30.037 33.977 -1.467 1.00 31.36 ? 1834 HOH A O 1 HETATM 8383 O O . HOH G 7 . ? 32.024 34.116 -3.143 1.00 25.25 ? 1835 HOH A O 1 HETATM 8384 O O . HOH G 7 . ? 33.171 36.406 -4.245 1.00 19.33 ? 1836 HOH A O 1 HETATM 8385 O O . HOH G 7 . ? 32.281 38.943 -4.791 1.00 14.82 ? 1837 HOH A O 1 HETATM 8386 O O . HOH G 7 . ? 35.940 35.815 -4.384 1.00 22.21 ? 1838 HOH A O 1 HETATM 8387 O O . HOH G 7 . ? 39.882 38.638 -3.398 1.00 27.01 ? 1839 HOH A O 1 HETATM 8388 O O . HOH G 7 . ? 39.920 39.483 -0.198 1.00 29.36 ? 1840 HOH A O 1 HETATM 8389 O O . HOH G 7 . ? 38.261 39.836 1.853 1.00 16.63 ? 1841 HOH A O 1 HETATM 8390 O O . HOH G 7 . ? 37.223 37.234 2.933 1.00 34.99 ? 1842 HOH A O 1 HETATM 8391 O O . HOH G 7 . ? 34.321 36.085 3.485 1.00 37.18 ? 1843 HOH A O 1 HETATM 8392 O O . HOH G 7 . ? 37.200 33.746 5.691 1.00 42.28 ? 1844 HOH A O 1 HETATM 8393 O O . HOH G 7 . ? 40.013 35.234 11.438 1.00 27.74 ? 1845 HOH A O 1 HETATM 8394 O O . HOH G 7 . ? 40.059 39.051 9.247 1.00 30.26 ? 1846 HOH A O 1 HETATM 8395 O O . HOH G 7 . ? 42.612 39.584 7.994 1.00 43.29 ? 1847 HOH A O 1 HETATM 8396 O O . HOH G 7 . ? 44.629 40.830 7.785 1.00 46.47 ? 1848 HOH A O 1 HETATM 8397 O O . HOH G 7 . ? 46.448 42.659 9.712 1.00 34.65 ? 1849 HOH A O 1 HETATM 8398 O O . HOH G 7 . ? 48.514 44.727 10.395 1.00 40.02 ? 1850 HOH A O 1 HETATM 8399 O O . HOH G 7 . ? 46.732 45.670 11.677 1.00 33.08 ? 1851 HOH A O 1 HETATM 8400 O O . HOH G 7 . ? 46.904 48.404 11.640 1.00 21.38 ? 1852 HOH A O 1 HETATM 8401 O O . HOH G 7 . ? 47.899 49.349 13.929 1.00 18.46 ? 1853 HOH A O 1 HETATM 8402 O O . HOH G 7 . ? 48.008 48.172 16.521 1.00 22.47 ? 1854 HOH A O 1 HETATM 8403 O O . HOH G 7 . ? 46.106 45.807 16.452 1.00 39.91 ? 1855 HOH A O 1 HETATM 8404 O O . HOH G 7 . ? 43.569 44.660 19.425 1.00 49.71 ? 1856 HOH A O 1 HETATM 8405 O O . HOH G 7 . ? 45.602 44.812 23.064 1.00 35.87 ? 1857 HOH A O 1 HETATM 8406 O O . HOH G 7 . ? 44.109 45.219 25.394 1.00 35.16 ? 1858 HOH A O 1 HETATM 8407 O O . HOH G 7 . ? 40.002 45.131 25.391 1.00 37.50 ? 1859 HOH A O 1 HETATM 8408 O O . HOH G 7 . ? 39.181 43.553 26.821 1.00 35.04 ? 1860 HOH A O 1 HETATM 8409 O O . HOH G 7 . ? 39.687 41.374 25.517 1.00 40.37 ? 1861 HOH A O 1 HETATM 8410 O O . HOH G 7 . ? 37.444 40.320 26.523 1.00 42.35 ? 1862 HOH A O 1 HETATM 8411 O O . HOH G 7 . ? 37.309 37.430 24.956 1.00 47.61 ? 1863 HOH A O 1 HETATM 8412 O O . HOH G 7 . ? 34.879 37.928 22.273 1.00 42.88 ? 1864 HOH A O 1 HETATM 8413 O O . HOH G 7 . ? 39.656 39.494 20.154 1.00 32.67 ? 1865 HOH A O 1 HETATM 8414 O O . HOH G 7 . ? 39.200 38.804 17.342 1.00 20.76 ? 1866 HOH A O 1 HETATM 8415 O O . HOH G 7 . ? 41.809 39.000 16.729 1.00 29.83 ? 1867 HOH A O 1 HETATM 8416 O O . HOH G 7 . ? 44.816 40.306 13.385 1.00 43.22 ? 1868 HOH A O 1 HETATM 8417 O O . HOH G 7 . ? 44.311 45.857 10.087 1.00 17.23 ? 1869 HOH A O 1 HETATM 8418 O O . HOH G 7 . ? 42.951 47.923 11.297 1.00 17.14 ? 1870 HOH A O 1 HETATM 8419 O O . HOH G 7 . ? 41.567 43.079 8.007 1.00 20.29 ? 1871 HOH A O 1 HETATM 8420 O O . HOH G 7 . ? 47.653 39.897 5.991 1.00 39.36 ? 1872 HOH A O 1 HETATM 8421 O O . HOH G 7 . ? 48.086 41.508 3.758 1.00 25.79 ? 1873 HOH A O 1 HETATM 8422 O O . HOH G 7 . ? 49.631 40.829 1.657 1.00 38.53 ? 1874 HOH A O 1 HETATM 8423 O O . HOH G 7 . ? 48.545 40.683 -0.876 1.00 29.52 ? 1875 HOH A O 1 HETATM 8424 O O . HOH G 7 . ? 47.434 42.699 -2.345 1.00 20.62 ? 1876 HOH A O 1 HETATM 8425 O O . HOH G 7 . ? 48.065 41.423 -5.360 1.00 32.12 ? 1877 HOH A O 1 HETATM 8426 O O . HOH G 7 . ? 48.707 43.969 -6.128 1.00 20.55 ? 1878 HOH A O 1 HETATM 8427 O O . HOH G 7 . ? 47.895 43.700 -8.567 1.00 23.95 ? 1879 HOH A O 1 HETATM 8428 O O . HOH G 7 . ? 45.578 41.796 -8.896 1.00 40.74 ? 1880 HOH A O 1 HETATM 8429 O O . HOH G 7 . ? 43.552 41.537 -7.543 1.00 29.98 ? 1881 HOH A O 1 HETATM 8430 O O . HOH G 7 . ? 42.080 40.384 -9.779 1.00 42.37 ? 1882 HOH A O 1 HETATM 8431 O O . HOH G 7 . ? 43.948 37.799 -9.746 1.00 46.09 ? 1883 HOH A O 1 HETATM 8432 O O . HOH G 7 . ? 43.222 38.334 -6.233 1.00 40.18 ? 1884 HOH A O 1 HETATM 8433 O O . HOH G 7 . ? 42.554 39.317 -1.310 1.00 32.81 ? 1885 HOH A O 1 HETATM 8434 O O . HOH G 7 . ? 44.506 41.619 -0.393 1.00 19.00 ? 1886 HOH A O 1 HETATM 8435 O O . HOH G 7 . ? 46.171 39.685 0.238 1.00 32.40 ? 1887 HOH A O 1 HETATM 8436 O O . HOH G 7 . ? 48.791 38.770 -2.897 1.00 45.43 ? 1888 HOH A O 1 HETATM 8437 O O . HOH G 7 . ? 50.948 44.072 -7.897 1.00 15.84 ? 1889 HOH A O 1 HETATM 8438 O O . HOH G 7 . ? 51.823 40.769 -12.960 1.00 34.90 ? 1890 HOH A O 1 HETATM 8439 O O . HOH G 7 . ? 47.134 41.216 -14.664 1.00 31.14 ? 1891 HOH A O 1 HETATM 8440 O O . HOH G 7 . ? 42.433 39.027 -15.518 1.00 30.99 ? 1892 HOH A O 1 HETATM 8441 O O . HOH G 7 . ? 41.529 40.918 -17.466 1.00 23.18 ? 1893 HOH A O 1 HETATM 8442 O O . HOH G 7 . ? 40.875 40.472 -21.331 1.00 31.46 ? 1894 HOH A O 1 HETATM 8443 O O . HOH G 7 . ? 38.655 41.949 -22.081 1.00 30.22 ? 1895 HOH A O 1 HETATM 8444 O O . HOH G 7 . ? 36.915 41.049 -24.591 1.00 34.34 ? 1896 HOH A O 1 HETATM 8445 O O . HOH G 7 . ? 38.329 39.860 -26.429 1.00 45.39 ? 1897 HOH A O 1 HETATM 8446 O O . HOH G 7 . ? 39.934 44.824 -26.359 1.00 42.58 ? 1898 HOH A O 1 HETATM 8447 O O . HOH G 7 . ? 41.408 44.423 -24.200 1.00 27.20 ? 1899 HOH A O 1 HETATM 8448 O O . HOH G 7 . ? 42.063 47.018 -24.402 1.00 19.09 ? 1900 HOH A O 1 HETATM 8449 O O . HOH G 7 . ? 42.657 47.197 -27.113 1.00 36.19 ? 1901 HOH A O 1 HETATM 8450 O O . HOH G 7 . ? 40.879 47.852 -29.223 1.00 37.16 ? 1902 HOH A O 1 HETATM 8451 O O . HOH G 7 . ? 39.448 48.371 -32.660 1.00 26.43 ? 1903 HOH A O 1 HETATM 8452 O O . HOH G 7 . ? 38.628 44.872 -33.550 1.00 25.71 ? 1904 HOH A O 1 HETATM 8453 O O . HOH G 7 . ? 35.454 44.908 -27.281 1.00 21.61 ? 1905 HOH A O 1 HETATM 8454 O O . HOH G 7 . ? 37.298 44.877 -25.321 1.00 25.22 ? 1906 HOH A O 1 HETATM 8455 O O . HOH G 7 . ? 43.374 42.489 -24.733 1.00 43.83 ? 1907 HOH A O 1 HETATM 8456 O O . HOH G 7 . ? 43.215 40.212 -22.897 1.00 37.82 ? 1908 HOH A O 1 HETATM 8457 O O . HOH G 7 . ? 48.584 45.679 -23.200 1.00 44.43 ? 1909 HOH A O 1 HETATM 8458 O O . HOH G 7 . ? 50.269 44.664 -24.673 1.00 39.62 ? 1910 HOH A O 1 HETATM 8459 O O . HOH G 7 . ? 52.191 45.089 -27.153 1.00 36.61 ? 1911 HOH A O 1 HETATM 8460 O O . HOH G 7 . ? 53.228 46.817 -24.986 1.00 24.52 ? 1912 HOH A O 1 HETATM 8461 O O . HOH G 7 . ? 50.058 46.872 -30.406 1.00 55.44 ? 1913 HOH A O 1 HETATM 8462 O O . HOH G 7 . ? 48.763 49.838 -29.217 1.00 33.05 ? 1914 HOH A O 1 HETATM 8463 O O . HOH G 7 . ? 47.700 49.569 -31.300 1.00 44.08 ? 1915 HOH A O 1 HETATM 8464 O O . HOH G 7 . ? 48.124 53.597 -31.226 1.00 47.68 ? 1916 HOH A O 1 HETATM 8465 O O . HOH G 7 . ? 49.782 54.832 -28.981 1.00 25.89 ? 1917 HOH A O 1 HETATM 8466 O O . HOH G 7 . ? 50.921 52.492 -28.469 1.00 24.24 ? 1918 HOH A O 1 HETATM 8467 O O . HOH G 7 . ? 53.242 53.051 -29.771 1.00 34.25 ? 1919 HOH A O 1 HETATM 8468 O O . HOH G 7 . ? 53.142 54.896 -31.860 1.00 36.48 ? 1920 HOH A O 1 HETATM 8469 O O . HOH G 7 . ? 52.044 56.102 -30.065 1.00 28.28 ? 1921 HOH A O 1 HETATM 8470 O O . HOH G 7 . ? 49.921 58.148 -30.840 1.00 46.13 ? 1922 HOH A O 1 HETATM 8471 O O . HOH G 7 . ? 49.041 59.004 -28.455 1.00 35.13 ? 1923 HOH A O 1 HETATM 8472 O O . HOH G 7 . ? 48.096 61.543 -28.403 1.00 32.70 ? 1924 HOH A O 1 HETATM 8473 O O . HOH G 7 . ? 47.016 61.878 -25.646 1.00 26.66 ? 1925 HOH A O 1 HETATM 8474 O O . HOH G 7 . ? 47.790 59.103 -25.584 1.00 18.45 ? 1926 HOH A O 1 HETATM 8475 O O . HOH G 7 . ? 46.844 55.418 -25.370 1.00 22.18 ? 1927 HOH A O 1 HETATM 8476 O O . HOH G 7 . ? 48.630 54.643 -22.637 1.00 23.54 ? 1928 HOH A O 1 HETATM 8477 O O . HOH G 7 . ? 46.819 53.625 -21.159 1.00 35.02 ? 1929 HOH A O 1 HETATM 8478 O O . HOH G 7 . ? 45.902 52.505 -19.027 1.00 21.90 ? 1930 HOH A O 1 HETATM 8479 O O . HOH G 7 . ? 44.952 54.834 -18.262 1.00 31.77 ? 1931 HOH A O 1 HETATM 8480 O O . HOH G 7 . ? 46.560 57.018 -18.680 1.00 17.33 ? 1932 HOH A O 1 HETATM 8481 O O . HOH G 7 . ? 45.650 59.613 -18.236 1.00 17.48 ? 1933 HOH A O 1 HETATM 8482 O O . HOH G 7 . ? 42.977 59.252 -18.876 1.00 24.49 ? 1934 HOH A O 1 HETATM 8483 O O . HOH G 7 . ? 41.590 58.414 -15.987 1.00 18.05 ? 1935 HOH A O 1 HETATM 8484 O O . HOH G 7 . ? 39.628 58.604 -17.932 1.00 23.93 ? 1936 HOH A O 1 HETATM 8485 O O . HOH G 7 . ? 40.189 56.022 -19.015 1.00 26.46 ? 1937 HOH A O 1 HETATM 8486 O O . HOH G 7 . ? 42.077 54.573 -17.319 1.00 29.14 ? 1938 HOH A O 1 HETATM 8487 O O . HOH G 7 . ? 40.975 52.029 -16.830 1.00 16.34 ? 1939 HOH A O 1 HETATM 8488 O O . HOH G 7 . ? 37.596 51.233 -18.470 1.00 23.88 ? 1940 HOH A O 1 HETATM 8489 O O . HOH G 7 . ? 37.569 51.819 -20.965 1.00 15.78 ? 1941 HOH A O 1 HETATM 8490 O O . HOH G 7 . ? 39.590 53.644 -20.637 1.00 20.15 ? 1942 HOH A O 1 HETATM 8491 O O . HOH G 7 . ? 35.049 50.282 -17.469 1.00 18.42 ? 1943 HOH A O 1 HETATM 8492 O O . HOH G 7 . ? 31.245 49.627 -23.893 1.00 17.23 ? 1944 HOH A O 1 HETATM 8493 O O . HOH G 7 . ? 28.629 49.452 -24.272 1.00 22.37 ? 1945 HOH A O 1 HETATM 8494 O O . HOH G 7 . ? 26.811 47.310 -23.900 1.00 36.35 ? 1946 HOH A O 1 HETATM 8495 O O . HOH G 7 . ? 27.499 48.157 -21.514 1.00 20.49 ? 1947 HOH A O 1 HETATM 8496 O O . HOH G 7 . ? 24.997 46.686 -20.568 1.00 26.35 ? 1948 HOH A O 1 HETATM 8497 O O . HOH G 7 . ? 23.945 48.128 -24.195 1.00 39.40 ? 1949 HOH A O 1 HETATM 8498 O O . HOH G 7 . ? 24.662 50.812 -23.930 1.00 19.35 ? 1950 HOH A O 1 HETATM 8499 O O . HOH G 7 . ? 22.795 52.793 -24.253 1.00 17.25 ? 1951 HOH A O 1 HETATM 8500 O O . HOH G 7 . ? 23.710 55.232 -23.281 1.00 14.57 ? 1952 HOH A O 1 HETATM 8501 O O . HOH G 7 . ? 19.958 52.416 -24.065 1.00 21.06 ? 1953 HOH A O 1 HETATM 8502 O O . HOH G 7 . ? 19.164 50.057 -23.287 1.00 34.10 ? 1954 HOH A O 1 HETATM 8503 O O . HOH G 7 . ? 16.467 52.606 -22.420 1.00 34.32 ? 1955 HOH A O 1 HETATM 8504 O O . HOH G 7 . ? 16.871 50.561 -19.135 1.00 26.09 ? 1956 HOH A O 1 HETATM 8505 O O . HOH G 7 . ? 18.036 48.356 -19.703 1.00 41.45 ? 1957 HOH A O 1 HETATM 8506 O O . HOH G 7 . ? 21.450 46.417 -17.381 1.00 31.79 ? 1958 HOH A O 1 HETATM 8507 O O . HOH G 7 . ? 23.594 45.706 -15.716 1.00 24.10 ? 1959 HOH A O 1 HETATM 8508 O O . HOH G 7 . ? 22.488 45.074 -13.335 1.00 21.18 ? 1960 HOH A O 1 HETATM 8509 O O . HOH G 7 . ? 22.000 42.358 -13.129 1.00 26.82 ? 1961 HOH A O 1 HETATM 8510 O O . HOH G 7 . ? 24.079 41.661 -14.447 1.00 27.00 ? 1962 HOH A O 1 HETATM 8511 O O . HOH G 7 . ? 26.618 41.331 -13.081 1.00 16.93 ? 1963 HOH A O 1 HETATM 8512 O O . HOH G 7 . ? 28.783 42.492 -11.828 1.00 16.32 ? 1964 HOH A O 1 HETATM 8513 O O . HOH G 7 . ? 31.702 46.768 -7.956 1.00 11.71 ? 1965 HOH A O 1 HETATM 8514 O O . HOH G 7 . ? 33.391 47.886 -10.033 1.00 12.27 ? 1966 HOH A O 1 HETATM 8515 O O . HOH G 7 . ? 36.669 44.667 -5.327 1.00 14.54 ? 1967 HOH A O 1 HETATM 8516 O O . HOH G 7 . ? 41.430 44.504 -6.770 1.00 18.73 ? 1968 HOH A O 1 HETATM 8517 O O . HOH G 7 . ? 39.428 37.965 -10.606 1.00 35.05 ? 1969 HOH A O 1 HETATM 8518 O O . HOH G 7 . ? 41.361 36.895 -12.477 1.00 45.11 ? 1970 HOH A O 1 HETATM 8519 O O . HOH G 7 . ? 36.789 34.889 -15.799 1.00 36.24 ? 1971 HOH A O 1 HETATM 8520 O O . HOH G 7 . ? 36.051 35.932 -18.123 1.00 41.02 ? 1972 HOH A O 1 HETATM 8521 O O . HOH G 7 . ? 35.763 38.762 -15.984 1.00 29.41 ? 1973 HOH A O 1 HETATM 8522 O O . HOH G 7 . ? 33.004 40.730 -17.818 1.00 29.19 ? 1974 HOH A O 1 HETATM 8523 O O . HOH G 7 . ? 25.567 35.888 -15.261 1.00 36.05 ? 1975 HOH A O 1 HETATM 8524 O O . HOH G 7 . ? 23.723 37.345 -17.496 1.00 40.06 ? 1976 HOH A O 1 HETATM 8525 O O . HOH G 7 . ? 22.914 39.030 -15.312 1.00 34.00 ? 1977 HOH A O 1 HETATM 8526 O O . HOH G 7 . ? 20.148 39.046 -12.112 1.00 45.30 ? 1978 HOH A O 1 HETATM 8527 O O . HOH G 7 . ? 19.561 41.766 -14.339 1.00 46.25 ? 1979 HOH A O 1 HETATM 8528 O O . HOH G 7 . ? 17.450 45.358 -13.863 1.00 36.69 ? 1980 HOH A O 1 HETATM 8529 O O . HOH G 7 . ? 19.872 46.476 -14.139 1.00 21.23 ? 1981 HOH A O 1 HETATM 8530 O O . HOH G 7 . ? 18.604 50.803 -12.330 1.00 16.34 ? 1982 HOH A O 1 HETATM 8531 O O . HOH G 7 . ? 19.603 53.228 -11.704 1.00 17.21 ? 1983 HOH A O 1 HETATM 8532 O O . HOH G 7 . ? 22.270 54.142 -11.893 1.00 15.00 ? 1984 HOH A O 1 HETATM 8533 O O . HOH G 7 . ? 24.689 52.639 -11.648 1.00 14.14 ? 1985 HOH A O 1 HETATM 8534 O O . HOH G 7 . ? 25.505 50.960 -9.335 1.00 17.39 ? 1986 HOH A O 1 HETATM 8535 O O . HOH G 7 . ? 22.861 51.554 -8.541 1.00 20.88 ? 1987 HOH A O 1 HETATM 8536 O O . HOH G 7 . ? 24.080 52.904 -6.191 1.00 26.22 ? 1988 HOH A O 1 HETATM 8537 O O . HOH G 7 . ? 23.289 53.715 -3.544 1.00 17.62 ? 1989 HOH A O 1 HETATM 8538 O O . HOH G 7 . ? 24.314 55.414 -1.686 1.00 15.98 ? 1990 HOH A O 1 HETATM 8539 O O . HOH G 7 . ? 20.593 57.188 -5.142 1.00 14.71 ? 1991 HOH A O 1 HETATM 8540 O O . HOH G 7 . ? 21.512 57.670 -7.660 1.00 14.80 ? 1992 HOH A O 1 HETATM 8541 O O . HOH G 7 . ? 19.749 57.078 -11.602 1.00 18.84 ? 1993 HOH A O 1 HETATM 8542 O O . HOH G 7 . ? 14.618 61.680 -14.383 1.00 25.32 ? 1994 HOH A O 1 HETATM 8543 O O . HOH G 7 . ? 14.223 62.612 -12.023 1.00 23.05 ? 1995 HOH A O 1 HETATM 8544 O O . HOH G 7 . ? 12.258 64.311 -12.342 1.00 30.84 ? 1996 HOH A O 1 HETATM 8545 O O . HOH G 7 . ? 10.657 62.283 -12.148 1.00 37.94 ? 1997 HOH A O 1 HETATM 8546 O O . HOH G 7 . ? 10.204 62.834 -14.588 1.00 36.98 ? 1998 HOH A O 1 HETATM 8547 O O . HOH G 7 . ? 11.744 63.357 -16.708 1.00 27.04 ? 1999 HOH A O 1 HETATM 8548 O O . HOH G 7 . ? 14.321 63.658 -16.231 1.00 19.98 ? 2000 HOH A O 1 HETATM 8549 O O . HOH G 7 . ? 13.315 62.045 -19.757 1.00 23.89 ? 2001 HOH A O 1 HETATM 8550 O O . HOH G 7 . ? 11.340 61.053 -18.297 1.00 24.20 ? 2002 HOH A O 1 HETATM 8551 O O . HOH G 7 . ? 9.730 60.054 -20.243 1.00 32.03 ? 2003 HOH A O 1 HETATM 8552 O O . HOH G 7 . ? 10.548 57.742 -20.859 1.00 41.32 ? 2004 HOH A O 1 HETATM 8553 O O . HOH G 7 . ? 13.845 60.472 -22.388 1.00 21.63 ? 2005 HOH A O 1 HETATM 8554 O O . HOH G 7 . ? 12.879 61.583 -24.925 1.00 41.41 ? 2006 HOH A O 1 HETATM 8555 O O . HOH G 7 . ? 14.990 63.308 -25.749 1.00 29.45 ? 2007 HOH A O 1 HETATM 8556 O O . HOH G 7 . ? 18.496 64.656 -26.906 1.00 24.29 ? 2008 HOH A O 1 HETATM 8557 O O . HOH G 7 . ? 16.966 66.907 -25.747 1.00 35.77 ? 2009 HOH A O 1 HETATM 8558 O O . HOH G 7 . ? 15.322 68.146 -27.299 1.00 38.27 ? 2010 HOH A O 1 HETATM 8559 O O . HOH G 7 . ? 17.178 69.765 -23.269 1.00 22.50 ? 2011 HOH A O 1 HETATM 8560 O O . HOH G 7 . ? 14.599 70.177 -22.925 1.00 29.87 ? 2012 HOH A O 1 HETATM 8561 O O . HOH G 7 . ? 14.988 73.354 -21.769 1.00 38.47 ? 2013 HOH A O 1 HETATM 8562 O O . HOH G 7 . ? 12.782 74.006 -23.021 1.00 41.61 ? 2014 HOH A O 1 HETATM 8563 O O . HOH G 7 . ? 16.235 74.761 -23.945 1.00 45.68 ? 2015 HOH A O 1 HETATM 8564 O O . HOH G 7 . ? 19.356 78.566 -25.464 1.00 34.25 ? 2016 HOH A O 1 HETATM 8565 O O . HOH G 7 . ? 20.739 78.085 -27.381 1.00 41.74 ? 2017 HOH A O 1 HETATM 8566 O O . HOH G 7 . ? 22.826 77.043 -27.257 1.00 31.31 ? 2018 HOH A O 1 HETATM 8567 O O . HOH G 7 . ? 23.199 78.090 -24.731 1.00 23.01 ? 2019 HOH A O 1 HETATM 8568 O O . HOH G 7 . ? 20.986 79.161 -23.417 1.00 27.64 ? 2020 HOH A O 1 HETATM 8569 O O . HOH G 7 . ? 19.074 82.882 -25.823 1.00 33.24 ? 2021 HOH A O 1 HETATM 8570 O O . HOH G 7 . ? 21.495 85.663 -30.898 1.00 35.77 ? 2022 HOH A O 1 HETATM 8571 O O . HOH G 7 . ? 23.245 86.709 -32.595 1.00 33.64 ? 2023 HOH A O 1 HETATM 8572 O O . HOH G 7 . ? 25.603 85.844 -31.900 1.00 22.43 ? 2024 HOH A O 1 HETATM 8573 O O . HOH G 7 . ? 27.051 89.396 -31.667 1.00 41.13 ? 2025 HOH A O 1 HETATM 8574 O O . HOH G 7 . ? 25.683 91.247 -32.842 1.00 40.87 ? 2026 HOH A O 1 HETATM 8575 O O . HOH G 7 . ? 28.120 93.240 -29.616 1.00 40.51 ? 2027 HOH A O 1 HETATM 8576 O O . HOH G 7 . ? 26.656 91.458 -27.456 1.00 40.26 ? 2028 HOH A O 1 HETATM 8577 O O . HOH G 7 . ? 28.116 90.576 -25.353 1.00 24.18 ? 2029 HOH A O 1 HETATM 8578 O O . HOH G 7 . ? 29.518 88.393 -26.237 1.00 18.21 ? 2030 HOH A O 1 HETATM 8579 O O . HOH G 7 . ? 26.980 87.582 -23.553 1.00 29.47 ? 2031 HOH A O 1 HETATM 8580 O O . HOH G 7 . ? 25.102 88.508 -25.198 1.00 38.57 ? 2032 HOH A O 1 HETATM 8581 O O . HOH G 7 . ? 23.623 90.565 -26.161 1.00 45.51 ? 2033 HOH A O 1 HETATM 8582 O O . HOH G 7 . ? 22.843 88.415 -18.657 1.00 44.40 ? 2034 HOH A O 1 HETATM 8583 O O . HOH G 7 . ? 21.383 85.904 -19.173 1.00 38.05 ? 2035 HOH A O 1 HETATM 8584 O O . HOH G 7 . ? 19.762 84.015 -18.351 1.00 34.44 ? 2036 HOH A O 1 HETATM 8585 O O . HOH G 7 . ? 22.864 84.806 -16.968 1.00 42.28 ? 2037 HOH A O 1 HETATM 8586 O O . HOH G 7 . ? 24.794 82.805 -16.839 1.00 25.94 ? 2038 HOH A O 1 HETATM 8587 O O . HOH G 7 . ? 27.723 85.964 -14.534 1.00 31.05 ? 2039 HOH A O 1 HETATM 8588 O O . HOH G 7 . ? 30.312 86.809 -15.100 1.00 28.37 ? 2040 HOH A O 1 HETATM 8589 O O . HOH G 7 . ? 29.707 86.982 -17.795 1.00 35.29 ? 2041 HOH A O 1 HETATM 8590 O O . HOH G 7 . ? 31.661 85.493 -19.888 1.00 27.44 ? 2042 HOH A O 1 HETATM 8591 O O . HOH G 7 . ? 33.327 84.035 -18.272 1.00 21.53 ? 2043 HOH A O 1 HETATM 8592 O O . HOH G 7 . ? 35.256 85.894 -17.916 1.00 30.87 ? 2044 HOH A O 1 HETATM 8593 O O . HOH G 7 . ? 34.755 87.868 -19.409 1.00 51.44 ? 2045 HOH A O 1 HETATM 8594 O O . HOH G 7 . ? 36.782 86.349 -15.711 1.00 41.16 ? 2046 HOH A O 1 HETATM 8595 O O . HOH G 7 . ? 40.783 85.008 -12.191 1.00 35.19 ? 2047 HOH A O 1 HETATM 8596 O O . HOH G 7 . ? 40.291 82.491 -10.674 1.00 22.68 ? 2048 HOH A O 1 HETATM 8597 O O . HOH G 7 . ? 42.964 82.064 -9.943 1.00 30.39 ? 2049 HOH A O 1 HETATM 8598 O O . HOH G 7 . ? 45.646 78.957 -7.865 1.00 31.02 ? 2050 HOH A O 1 HETATM 8599 O O . HOH G 7 . ? 47.564 80.938 -9.199 1.00 46.51 ? 2051 HOH A O 1 HETATM 8600 O O . HOH G 7 . ? 48.342 77.690 -9.750 1.00 31.15 ? 2052 HOH A O 1 HETATM 8601 O O . HOH G 7 . ? 50.170 79.391 -11.151 1.00 51.41 ? 2053 HOH A O 1 HETATM 8602 O O . HOH G 7 . ? 52.866 77.145 -11.078 1.00 42.74 ? 2054 HOH A O 1 HETATM 8603 O O . HOH G 7 . ? 52.727 75.955 -13.778 1.00 47.30 ? 2055 HOH A O 1 HETATM 8604 O O . HOH G 7 . ? 50.448 79.001 -15.790 1.00 35.84 ? 2056 HOH A O 1 HETATM 8605 O O . HOH G 7 . ? 52.498 78.740 -17.475 1.00 26.44 ? 2057 HOH A O 1 HETATM 8606 O O . HOH G 7 . ? 55.006 80.219 -19.302 1.00 28.09 ? 2058 HOH A O 1 HETATM 8607 O O . HOH G 7 . ? 57.195 80.015 -17.836 1.00 44.17 ? 2059 HOH A O 1 HETATM 8608 O O . HOH G 7 . ? 56.121 78.607 -14.565 1.00 37.52 ? 2060 HOH A O 1 HETATM 8609 O O . HOH G 7 . ? 61.215 77.171 -12.865 1.00 27.17 ? 2061 HOH A O 1 HETATM 8610 O O . HOH G 7 . ? 61.778 76.043 -10.491 1.00 23.26 ? 2062 HOH A O 1 HETATM 8611 O O . HOH G 7 . ? 59.491 76.227 -8.938 1.00 21.54 ? 2063 HOH A O 1 HETATM 8612 O O . HOH G 7 . ? 59.815 76.438 -4.176 1.00 40.43 ? 2064 HOH A O 1 HETATM 8613 O O . HOH G 7 . ? 57.190 75.117 -2.872 1.00 37.61 ? 2065 HOH A O 1 HETATM 8614 O O . HOH G 7 . ? 56.930 75.712 0.076 1.00 40.20 ? 2066 HOH A O 1 HETATM 8615 O O . HOH G 7 . ? 58.977 77.517 0.627 1.00 42.75 ? 2067 HOH A O 1 HETATM 8616 O O . HOH G 7 . ? 64.431 77.008 0.288 1.00 40.44 ? 2068 HOH A O 1 HETATM 8617 O O . HOH G 7 . ? 64.713 78.597 -1.484 1.00 35.54 ? 2069 HOH A O 1 HETATM 8618 O O . HOH G 7 . ? 65.331 78.407 -5.674 1.00 34.50 ? 2070 HOH A O 1 HETATM 8619 O O . HOH G 7 . ? 65.036 79.636 -8.796 1.00 41.93 ? 2071 HOH A O 1 HETATM 8620 O O . HOH G 7 . ? 67.034 81.223 -11.341 1.00 40.72 ? 2072 HOH A O 1 HETATM 8621 O O . HOH G 7 . ? 66.455 81.526 -14.252 1.00 36.89 ? 2073 HOH A O 1 HETATM 8622 O O . HOH G 7 . ? 63.679 81.893 -14.287 1.00 43.57 ? 2074 HOH A O 1 HETATM 8623 O O . HOH G 7 . ? 62.684 82.334 -17.023 1.00 41.53 ? 2075 HOH A O 1 HETATM 8624 O O . HOH G 7 . ? 61.995 80.382 -18.828 1.00 28.61 ? 2076 HOH A O 1 HETATM 8625 O O . HOH G 7 . ? 62.386 83.059 -21.558 1.00 43.81 ? 2077 HOH A O 1 HETATM 8626 O O . HOH G 7 . ? 62.040 85.258 -22.773 1.00 33.34 ? 2078 HOH A O 1 HETATM 8627 O O . HOH G 7 . ? 64.893 87.361 -24.167 1.00 34.92 ? 2079 HOH A O 1 HETATM 8628 O O . HOH G 7 . ? 67.608 87.658 -23.317 1.00 27.67 ? 2080 HOH A O 1 HETATM 8629 O O . HOH G 7 . ? 66.631 84.185 -22.294 1.00 37.24 ? 2081 HOH A O 1 HETATM 8630 O O . HOH G 7 . ? 67.733 81.321 -25.645 1.00 17.06 ? 2082 HOH A O 1 HETATM 8631 O O . HOH G 7 . ? 67.717 78.597 -25.262 1.00 17.84 ? 2083 HOH A O 1 HETATM 8632 O O . HOH G 7 . ? 70.387 77.731 -26.053 1.00 30.80 ? 2084 HOH A O 1 HETATM 8633 O O . HOH G 7 . ? 72.362 75.601 -26.932 1.00 43.54 ? 2085 HOH A O 1 HETATM 8634 O O . HOH G 7 . ? 71.719 73.486 -29.084 1.00 32.15 ? 2086 HOH A O 1 HETATM 8635 O O . HOH G 7 . ? 70.801 72.122 -34.121 1.00 41.31 ? 2087 HOH A O 1 HETATM 8636 O O . HOH G 7 . ? 67.842 74.710 -35.072 1.00 39.39 ? 2088 HOH A O 1 HETATM 8637 O O . HOH G 7 . ? 69.171 76.720 -34.157 1.00 28.71 ? 2089 HOH A O 1 HETATM 8638 O O . HOH G 7 . ? 71.476 76.346 -35.595 1.00 41.52 ? 2090 HOH A O 1 HETATM 8639 O O . HOH G 7 . ? 68.311 79.277 -34.771 1.00 29.19 ? 2091 HOH A O 1 HETATM 8640 O O . HOH G 7 . ? 69.802 81.603 -33.960 1.00 39.77 ? 2092 HOH A O 1 HETATM 8641 O O . HOH G 7 . ? 69.298 83.529 -35.909 1.00 35.01 ? 2093 HOH A O 1 HETATM 8642 O O . HOH G 7 . ? 67.391 85.285 -36.112 1.00 39.68 ? 2094 HOH A O 1 HETATM 8643 O O . HOH G 7 . ? 67.804 87.875 -35.146 1.00 39.58 ? 2095 HOH A O 1 HETATM 8644 O O . HOH G 7 . ? 65.354 87.259 -41.206 1.00 39.51 ? 2096 HOH A O 1 HETATM 8645 O O . HOH G 7 . ? 61.909 82.690 -38.315 1.00 30.90 ? 2097 HOH A O 1 HETATM 8646 O O . HOH G 7 . ? 63.853 78.148 -37.851 1.00 35.99 ? 2098 HOH A O 1 HETATM 8647 O O . HOH G 7 . ? 64.235 77.550 -35.242 1.00 18.75 ? 2099 HOH A O 1 HETATM 8648 O O . HOH G 7 . ? 67.684 76.961 -38.737 1.00 40.86 ? 2100 HOH A O 1 HETATM 8649 O O . HOH G 7 . ? 63.956 76.554 -40.510 1.00 36.74 ? 2101 HOH A O 1 HETATM 8650 O O . HOH G 7 . ? 61.311 76.343 -39.708 1.00 23.44 ? 2102 HOH A O 1 HETATM 8651 O O . HOH G 7 . ? 60.662 78.477 -41.502 1.00 30.05 ? 2103 HOH A O 1 HETATM 8652 O O . HOH G 7 . ? 62.141 81.114 -44.269 1.00 38.58 ? 2104 HOH A O 1 HETATM 8653 O O . HOH G 7 . ? 59.269 86.575 -45.685 1.00 45.40 ? 2105 HOH A O 1 HETATM 8654 O O . HOH G 7 . ? 56.605 89.574 -43.529 1.00 37.07 ? 2106 HOH A O 1 HETATM 8655 O O . HOH G 7 . ? 60.271 92.905 -37.997 1.00 38.75 ? 2107 HOH A O 1 HETATM 8656 O O . HOH G 7 . ? 61.289 90.459 -37.083 1.00 39.82 ? 2108 HOH A O 1 HETATM 8657 O O . HOH G 7 . ? 59.500 90.749 -35.358 1.00 27.79 ? 2109 HOH A O 1 HETATM 8658 O O . HOH G 7 . ? 56.329 92.450 -29.670 1.00 34.08 ? 2110 HOH A O 1 HETATM 8659 O O . HOH G 7 . ? 58.721 92.740 -27.011 1.00 46.55 ? 2111 HOH A O 1 HETATM 8660 O O . HOH G 7 . ? 57.856 92.976 -24.870 1.00 36.83 ? 2112 HOH A O 1 HETATM 8661 O O . HOH G 7 . ? 56.224 90.637 -25.824 1.00 30.20 ? 2113 HOH A O 1 HETATM 8662 O O . HOH G 7 . ? 54.851 89.893 -23.561 1.00 30.28 ? 2114 HOH A O 1 HETATM 8663 O O . HOH G 7 . ? 52.578 91.651 -23.527 1.00 35.89 ? 2115 HOH A O 1 HETATM 8664 O O . HOH G 7 . ? 50.732 90.389 -21.630 1.00 46.94 ? 2116 HOH A O 1 HETATM 8665 O O . HOH G 7 . ? 49.245 91.495 -24.517 1.00 38.19 ? 2117 HOH A O 1 HETATM 8666 O O . HOH G 7 . ? 46.844 89.155 -23.618 1.00 36.44 ? 2118 HOH A O 1 HETATM 8667 O O . HOH G 7 . ? 44.942 89.637 -25.518 1.00 26.17 ? 2119 HOH A O 1 HETATM 8668 O O . HOH G 7 . ? 44.906 92.295 -25.427 1.00 35.15 ? 2120 HOH A O 1 HETATM 8669 O O . HOH G 7 . ? 42.733 94.008 -30.288 1.00 42.12 ? 2121 HOH A O 1 HETATM 8670 O O . HOH G 7 . ? 40.033 99.382 -32.051 1.00 37.83 ? 2122 HOH A O 1 HETATM 8671 O O . HOH G 7 . ? 42.988 97.736 -37.098 1.00 37.48 ? 2123 HOH A O 1 HETATM 8672 O O . HOH G 7 . ? 40.705 95.835 -37.396 1.00 29.34 ? 2124 HOH A O 1 HETATM 8673 O O . HOH G 7 . ? 41.378 94.410 -39.433 1.00 34.41 ? 2125 HOH A O 1 HETATM 8674 O O . HOH G 7 . ? 43.454 93.408 -37.674 1.00 24.92 ? 2126 HOH A O 1 HETATM 8675 O O . HOH G 7 . ? 46.989 95.021 -37.124 1.00 45.12 ? 2127 HOH A O 1 HETATM 8676 O O . HOH G 7 . ? 48.638 97.391 -33.934 1.00 41.24 ? 2128 HOH A O 1 HETATM 8677 O O . HOH G 7 . ? 47.213 99.345 -32.746 1.00 41.53 ? 2129 HOH A O 1 HETATM 8678 O O . HOH G 7 . ? 48.239 88.815 -30.782 1.00 18.43 ? 2130 HOH A O 1 HETATM 8679 O O . HOH G 7 . ? 44.339 83.373 -28.048 1.00 33.82 ? 2131 HOH A O 1 HETATM 8680 O O . HOH G 7 . ? 42.152 82.122 -29.223 1.00 37.92 ? 2132 HOH A O 1 HETATM 8681 O O . HOH G 7 . ? 40.866 82.490 -31.359 1.00 33.13 ? 2133 HOH A O 1 HETATM 8682 O O . HOH G 7 . ? 38.110 81.344 -31.329 1.00 17.64 ? 2134 HOH A O 1 HETATM 8683 O O . HOH G 7 . ? 39.144 82.971 -27.476 1.00 28.60 ? 2135 HOH A O 1 HETATM 8684 O O . HOH G 7 . ? 43.456 80.607 -25.531 1.00 36.24 ? 2136 HOH A O 1 HETATM 8685 O O . HOH G 7 . ? 45.876 81.531 -25.706 1.00 50.68 ? 2137 HOH A O 1 HETATM 8686 O O . HOH G 7 . ? 46.772 80.269 -22.381 1.00 45.96 ? 2138 HOH A O 1 HETATM 8687 O O . HOH G 7 . ? 47.008 82.786 -20.990 1.00 44.70 ? 2139 HOH A O 1 HETATM 8688 O O . HOH G 7 . ? 48.681 84.098 -19.675 1.00 45.91 ? 2140 HOH A O 1 HETATM 8689 O O . HOH G 7 . ? 47.451 79.305 -18.281 1.00 30.24 ? 2141 HOH A O 1 HETATM 8690 O O . HOH G 7 . ? 43.872 79.288 -21.565 1.00 40.57 ? 2142 HOH A O 1 HETATM 8691 O O . HOH G 7 . ? 41.809 78.994 -23.429 1.00 31.63 ? 2143 HOH A O 1 HETATM 8692 O O . HOH G 7 . ? 39.561 81.366 -22.072 1.00 41.94 ? 2144 HOH A O 1 HETATM 8693 O O . HOH G 7 . ? 39.948 85.684 -21.872 1.00 28.23 ? 2145 HOH A O 1 HETATM 8694 O O . HOH G 7 . ? 42.635 78.583 -29.084 1.00 44.65 ? 2146 HOH A O 1 HETATM 8695 O O . HOH G 7 . ? 42.543 79.459 -31.782 1.00 35.18 ? 2147 HOH A O 1 HETATM 8696 O O . HOH G 7 . ? 44.592 78.863 -33.256 1.00 26.46 ? 2148 HOH A O 1 HETATM 8697 O O . HOH G 7 . ? 44.702 82.190 -30.604 1.00 28.23 ? 2149 HOH A O 1 HETATM 8698 O O . HOH G 7 . ? 46.328 76.743 -26.012 1.00 33.35 ? 2150 HOH A O 1 HETATM 8699 O O . HOH G 7 . ? 50.480 73.370 -25.485 1.00 25.96 ? 2151 HOH A O 1 HETATM 8700 O O . HOH G 7 . ? 51.056 70.589 -23.642 1.00 25.60 ? 2152 HOH A O 1 HETATM 8701 O O . HOH G 7 . ? 51.217 71.115 -20.314 1.00 27.51 ? 2153 HOH A O 1 HETATM 8702 O O . HOH G 7 . ? 53.574 72.264 -19.190 1.00 18.52 ? 2154 HOH A O 1 HETATM 8703 O O . HOH G 7 . ? 49.842 70.431 -17.691 1.00 34.53 ? 2155 HOH A O 1 HETATM 8704 O O . HOH G 7 . ? 46.896 72.065 -17.418 1.00 32.58 ? 2156 HOH A O 1 HETATM 8705 O O . HOH G 7 . ? 47.472 71.669 -19.909 1.00 38.09 ? 2157 HOH A O 1 HETATM 8706 O O . HOH G 7 . ? 45.605 69.807 -18.298 1.00 41.43 ? 2158 HOH A O 1 HETATM 8707 O O . HOH G 7 . ? 46.428 67.344 -15.559 1.00 20.72 ? 2159 HOH A O 1 HETATM 8708 O O . HOH G 7 . ? 39.221 64.477 -14.746 1.00 13.89 ? 2160 HOH A O 1 HETATM 8709 O O . HOH G 7 . ? 39.133 62.586 -19.048 1.00 12.09 ? 2161 HOH A O 1 HETATM 8710 O O . HOH G 7 . ? 44.517 58.444 -15.886 1.00 17.59 ? 2162 HOH A O 1 HETATM 8711 O O . HOH G 7 . ? 44.423 55.798 -15.284 1.00 21.69 ? 2163 HOH A O 1 HETATM 8712 O O . HOH G 7 . ? 47.226 55.521 -15.323 1.00 18.78 ? 2164 HOH A O 1 HETATM 8713 O O . HOH G 7 . ? 49.999 59.250 -11.475 1.00 14.66 ? 2165 HOH A O 1 HETATM 8714 O O . HOH G 7 . ? 50.809 59.627 -8.895 1.00 15.65 ? 2166 HOH A O 1 HETATM 8715 O O . HOH G 7 . ? 49.534 62.039 -8.584 1.00 14.10 ? 2167 HOH A O 1 HETATM 8716 O O . HOH G 7 . ? 53.592 59.617 -9.295 1.00 14.71 ? 2168 HOH A O 1 HETATM 8717 O O . HOH G 7 . ? 55.558 59.058 -11.415 1.00 14.12 ? 2169 HOH A O 1 HETATM 8718 O O . HOH G 7 . ? 60.996 59.411 -8.181 1.00 12.69 ? 2170 HOH A O 1 HETATM 8719 O O . HOH G 7 . ? 59.496 60.343 -6.151 1.00 17.53 ? 2171 HOH A O 1 HETATM 8720 O O . HOH G 7 . ? 60.629 60.585 -3.561 1.00 16.62 ? 2172 HOH A O 1 HETATM 8721 O O . HOH G 7 . ? 60.737 58.032 -2.739 1.00 16.59 ? 2173 HOH A O 1 HETATM 8722 O O . HOH G 7 . ? 63.122 58.423 -1.383 1.00 20.27 ? 2174 HOH A O 1 HETATM 8723 O O . HOH G 7 . ? 64.860 59.071 -3.521 1.00 18.21 ? 2175 HOH A O 1 HETATM 8724 O O . HOH G 7 . ? 63.059 60.872 -4.810 1.00 18.18 ? 2176 HOH A O 1 HETATM 8725 O O . HOH G 7 . ? 63.093 61.040 -7.528 1.00 14.21 ? 2177 HOH A O 1 HETATM 8726 O O . HOH G 7 . ? 65.623 60.033 -7.608 1.00 16.05 ? 2178 HOH A O 1 HETATM 8727 O O . HOH G 7 . ? 67.433 60.430 -5.522 1.00 16.51 ? 2179 HOH A O 1 HETATM 8728 O O . HOH G 7 . ? 68.752 57.987 -4.998 1.00 17.85 ? 2180 HOH A O 1 HETATM 8729 O O . HOH G 7 . ? 69.083 61.162 -2.325 1.00 19.69 ? 2181 HOH A O 1 HETATM 8730 O O . HOH G 7 . ? 70.297 61.747 0.094 1.00 43.26 ? 2182 HOH A O 1 HETATM 8731 O O . HOH G 7 . ? 71.337 59.351 0.788 1.00 39.48 ? 2183 HOH A O 1 HETATM 8732 O O . HOH G 7 . ? 73.555 62.843 -0.605 1.00 39.63 ? 2184 HOH A O 1 HETATM 8733 O O . HOH G 7 . ? 69.195 63.551 2.033 1.00 39.50 ? 2185 HOH A O 1 HETATM 8734 O O . HOH G 7 . ? 68.041 66.651 1.105 1.00 42.18 ? 2186 HOH A O 1 HETATM 8735 O O . HOH G 7 . ? 65.860 65.918 -0.328 1.00 29.09 ? 2187 HOH A O 1 HETATM 8736 O O . HOH G 7 . ? 67.940 65.299 -3.353 1.00 19.05 ? 2188 HOH A O 1 HETATM 8737 O O . HOH G 7 . ? 64.077 70.417 -5.251 1.00 19.85 ? 2189 HOH A O 1 HETATM 8738 O O . HOH G 7 . ? 66.395 71.221 -6.763 1.00 24.06 ? 2190 HOH A O 1 HETATM 8739 O O . HOH G 7 . ? 66.675 74.336 -4.414 1.00 32.64 ? 2191 HOH A O 1 HETATM 8740 O O . HOH G 7 . ? 73.512 73.891 -5.715 1.00 29.88 ? 2192 HOH A O 1 HETATM 8741 O O . HOH G 7 . ? 78.261 71.434 -10.084 1.00 35.47 ? 2193 HOH A O 1 HETATM 8742 O O . HOH G 7 . ? 78.652 68.815 -11.825 1.00 27.61 ? 2194 HOH A O 1 HETATM 8743 O O . HOH G 7 . ? 81.204 68.221 -11.343 1.00 25.50 ? 2195 HOH A O 1 HETATM 8744 O O . HOH G 7 . ? 81.640 66.782 -13.599 1.00 24.93 ? 2196 HOH A O 1 HETATM 8745 O O . HOH G 7 . ? 83.608 66.074 -15.334 1.00 24.27 ? 2197 HOH A O 1 HETATM 8746 O O . HOH G 7 . ? 84.285 68.012 -17.210 1.00 21.59 ? 2198 HOH A O 1 HETATM 8747 O O . HOH G 7 . ? 83.646 69.809 -20.146 1.00 31.66 ? 2199 HOH A O 1 HETATM 8748 O O . HOH G 7 . ? 83.567 67.174 -22.706 1.00 28.31 ? 2200 HOH A O 1 HETATM 8749 O O . HOH G 7 . ? 80.328 63.775 -21.113 1.00 28.76 ? 2201 HOH A O 1 HETATM 8750 O O . HOH G 7 . ? 78.994 62.602 -23.320 1.00 48.94 ? 2202 HOH A O 1 HETATM 8751 O O . HOH G 7 . ? 72.852 63.708 -20.865 1.00 32.55 ? 2203 HOH A O 1 HETATM 8752 O O . HOH G 7 . ? 71.766 62.365 -17.940 1.00 35.89 ? 2204 HOH A O 1 HETATM 8753 O O . HOH G 7 . ? 70.138 61.512 -20.338 1.00 30.60 ? 2205 HOH A O 1 HETATM 8754 O O . HOH G 7 . ? 69.811 62.638 -23.734 1.00 39.01 ? 2206 HOH A O 1 HETATM 8755 O O . HOH G 7 . ? 67.917 58.424 -24.022 1.00 25.46 ? 2207 HOH A O 1 HETATM 8756 O O . HOH G 7 . ? 68.021 56.354 -22.230 1.00 39.01 ? 2208 HOH A O 1 HETATM 8757 O O . HOH G 7 . ? 66.560 55.893 -20.165 1.00 22.01 ? 2209 HOH A O 1 HETATM 8758 O O . HOH G 7 . ? 67.604 54.399 -18.204 1.00 28.55 ? 2210 HOH A O 1 HETATM 8759 O O . HOH G 7 . ? 69.701 53.432 -19.646 1.00 38.36 ? 2211 HOH A O 1 HETATM 8760 O O . HOH G 7 . ? 65.812 52.466 -20.908 1.00 42.76 ? 2212 HOH A O 1 HETATM 8761 O O . HOH G 7 . ? 64.465 49.414 -21.570 1.00 38.76 ? 2213 HOH A O 1 HETATM 8762 O O . HOH G 7 . ? 62.336 47.831 -20.822 1.00 42.35 ? 2214 HOH A O 1 HETATM 8763 O O . HOH G 7 . ? 60.808 46.665 -22.278 1.00 35.37 ? 2215 HOH A O 1 HETATM 8764 O O . HOH G 7 . ? 63.105 42.665 -20.808 1.00 30.08 ? 2216 HOH A O 1 HETATM 8765 O O . HOH G 7 . ? 57.008 42.947 -19.749 1.00 30.85 ? 2217 HOH A O 1 HETATM 8766 O O . HOH G 7 . ? 56.437 45.907 -17.303 1.00 21.13 ? 2218 HOH A O 1 HETATM 8767 O O . HOH G 7 . ? 63.759 49.874 -13.909 1.00 18.17 ? 2219 HOH A O 1 HETATM 8768 O O . HOH G 7 . ? 68.497 46.717 -16.515 1.00 33.22 ? 2220 HOH A O 1 HETATM 8769 O O . HOH G 7 . ? 72.004 46.890 -17.779 1.00 37.14 ? 2221 HOH A O 1 HETATM 8770 O O . HOH G 7 . ? 71.032 42.851 -15.377 1.00 36.61 ? 2222 HOH A O 1 HETATM 8771 O O . HOH G 7 . ? 69.243 41.514 -17.186 1.00 34.82 ? 2223 HOH A O 1 HETATM 8772 O O . HOH G 7 . ? 67.077 38.271 -9.531 1.00 37.11 ? 2224 HOH A O 1 HETATM 8773 O O . HOH G 7 . ? 64.342 39.162 -10.060 1.00 27.30 ? 2225 HOH A O 1 HETATM 8774 O O . HOH G 7 . ? 63.462 44.414 -6.689 1.00 21.18 ? 2226 HOH A O 1 HETATM 8775 O O . HOH G 7 . ? 63.508 45.683 -3.160 1.00 48.57 ? 2227 HOH A O 1 HETATM 8776 O O . HOH G 7 . ? 66.023 45.297 -3.048 1.00 37.11 ? 2228 HOH A O 1 HETATM 8777 O O . HOH G 7 . ? 67.382 46.347 -1.263 1.00 29.03 ? 2229 HOH A O 1 HETATM 8778 O O . HOH G 7 . ? 68.108 49.088 -0.984 1.00 26.79 ? 2230 HOH A O 1 HETATM 8779 O O . HOH G 7 . ? 65.986 50.036 0.415 1.00 42.90 ? 2231 HOH A O 1 HETATM 8780 O O . HOH G 7 . ? 63.353 51.915 -0.223 1.00 38.54 ? 2232 HOH A O 1 HETATM 8781 O O . HOH G 7 . ? 60.497 54.545 -0.311 1.00 19.06 ? 2233 HOH A O 1 HETATM 8782 O O . HOH G 7 . ? 58.855 56.465 -1.345 1.00 17.15 ? 2234 HOH A O 1 HETATM 8783 O O . HOH G 7 . ? 58.902 57.890 0.962 1.00 29.37 ? 2235 HOH A O 1 HETATM 8784 O O . HOH G 7 . ? 56.542 58.288 1.408 1.00 29.13 ? 2236 HOH A O 1 HETATM 8785 O O . HOH G 7 . ? 56.860 60.782 1.623 1.00 18.92 ? 2237 HOH A O 1 HETATM 8786 O O . HOH G 7 . ? 55.174 58.793 3.969 1.00 20.26 ? 2238 HOH A O 1 HETATM 8787 O O . HOH G 7 . ? 57.440 58.299 5.538 1.00 30.66 ? 2239 HOH A O 1 HETATM 8788 O O . HOH G 7 . ? 58.600 60.292 5.915 1.00 35.41 ? 2240 HOH A O 1 HETATM 8789 O O . HOH G 7 . ? 57.688 62.195 7.892 1.00 28.26 ? 2241 HOH A O 1 HETATM 8790 O O . HOH G 7 . ? 56.593 66.817 5.150 1.00 38.24 ? 2242 HOH A O 1 HETATM 8791 O O . HOH G 7 . ? 54.950 68.368 3.639 1.00 40.97 ? 2243 HOH A O 1 HETATM 8792 O O . HOH G 7 . ? 52.023 68.686 4.069 1.00 39.27 ? 2244 HOH A O 1 HETATM 8793 O O . HOH G 7 . ? 49.853 67.303 4.345 1.00 26.21 ? 2245 HOH A O 1 HETATM 8794 O O . HOH G 7 . ? 49.274 67.876 6.698 1.00 32.20 ? 2246 HOH A O 1 HETATM 8795 O O . HOH G 7 . ? 51.288 66.187 8.586 1.00 28.68 ? 2247 HOH A O 1 HETATM 8796 O O . HOH G 7 . ? 53.175 67.704 9.064 1.00 36.27 ? 2248 HOH A O 1 HETATM 8797 O O . HOH G 7 . ? 52.595 70.424 8.967 1.00 37.09 ? 2249 HOH A O 1 HETATM 8798 O O . HOH G 7 . ? 50.353 72.058 9.208 1.00 22.83 ? 2250 HOH A O 1 HETATM 8799 O O . HOH G 7 . ? 51.248 74.342 8.502 1.00 41.79 ? 2251 HOH A O 1 HETATM 8800 O O . HOH G 7 . ? 48.245 76.347 8.248 1.00 38.53 ? 2252 HOH A O 1 HETATM 8801 O O . HOH G 7 . ? 46.113 77.368 9.477 1.00 25.79 ? 2253 HOH A O 1 HETATM 8802 O O . HOH G 7 . ? 47.287 78.132 11.652 1.00 33.66 ? 2254 HOH A O 1 HETATM 8803 O O . HOH G 7 . ? 47.086 77.290 14.179 1.00 40.96 ? 2255 HOH A O 1 HETATM 8804 O O . HOH G 7 . ? 50.905 76.113 14.367 1.00 25.95 ? 2256 HOH A O 1 HETATM 8805 O O . HOH G 7 . ? 51.693 77.458 11.819 1.00 46.43 ? 2257 HOH A O 1 HETATM 8806 O O . HOH G 7 . ? 49.201 76.356 5.349 1.00 34.75 ? 2258 HOH A O 1 HETATM 8807 O O . HOH G 7 . ? 50.599 77.123 2.145 1.00 40.37 ? 2259 HOH A O 1 HETATM 8808 O O . HOH G 7 . ? 52.381 75.284 1.870 1.00 46.60 ? 2260 HOH A O 1 HETATM 8809 O O . HOH G 7 . ? 52.627 72.848 3.996 1.00 37.07 ? 2261 HOH A O 1 HETATM 8810 O O . HOH G 7 . ? 52.347 70.663 5.972 1.00 33.50 ? 2262 HOH A O 1 HETATM 8811 O O . HOH G 7 . ? 56.211 71.153 3.714 1.00 43.13 ? 2263 HOH A O 1 HETATM 8812 O O . HOH G 7 . ? 59.148 68.093 2.549 1.00 28.33 ? 2264 HOH A O 1 HETATM 8813 O O . HOH G 7 . ? 60.441 61.987 -1.210 1.00 18.23 ? 2265 HOH A O 1 HETATM 8814 O O . HOH G 7 . ? 62.165 60.443 0.588 1.00 35.67 ? 2266 HOH A O 1 HETATM 8815 O O . HOH G 7 . ? 63.878 56.640 0.841 1.00 34.54 ? 2267 HOH A O 1 HETATM 8816 O O . HOH G 7 . ? 60.733 55.865 2.163 1.00 40.27 ? 2268 HOH A O 1 HETATM 8817 O O . HOH G 7 . ? 59.316 51.714 2.675 1.00 30.83 ? 2269 HOH A O 1 HETATM 8818 O O . HOH G 7 . ? 58.449 52.661 4.854 1.00 28.14 ? 2270 HOH A O 1 HETATM 8819 O O . HOH G 7 . ? 60.222 51.127 6.270 1.00 38.95 ? 2271 HOH A O 1 HETATM 8820 O O . HOH G 7 . ? 59.338 48.636 2.321 1.00 37.07 ? 2272 HOH A O 1 HETATM 8821 O O . HOH G 7 . ? 59.294 49.823 -0.615 1.00 22.30 ? 2273 HOH A O 1 HETATM 8822 O O . HOH G 7 . ? 58.702 52.438 -0.027 1.00 17.53 ? 2274 HOH A O 1 HETATM 8823 O O . HOH G 7 . ? 56.121 53.168 -0.565 1.00 13.01 ? 2275 HOH A O 1 HETATM 8824 O O . HOH G 7 . ? 56.274 55.550 -2.043 1.00 13.70 ? 2276 HOH A O 1 HETATM 8825 O O . HOH G 7 . ? 54.933 57.335 -0.433 1.00 17.78 ? 2277 HOH A O 1 HETATM 8826 O O . HOH G 7 . ? 52.724 58.693 -1.682 1.00 17.76 ? 2278 HOH A O 1 HETATM 8827 O O . HOH G 7 . ? 51.414 56.459 -5.537 1.00 13.90 ? 2279 HOH A O 1 HETATM 8828 O O . HOH G 7 . ? 49.714 57.378 -7.500 1.00 15.15 ? 2280 HOH A O 1 HETATM 8829 O O . HOH G 7 . ? 52.149 53.861 -4.803 1.00 12.90 ? 2281 HOH A O 1 HETATM 8830 O O . HOH G 7 . ? 49.799 48.240 1.450 1.00 14.16 ? 2282 HOH A O 1 HETATM 8831 O O . HOH G 7 . ? 51.868 46.292 1.364 1.00 17.40 ? 2283 HOH A O 1 HETATM 8832 O O . HOH G 7 . ? 51.546 44.237 3.129 1.00 29.13 ? 2284 HOH A O 1 HETATM 8833 O O . HOH G 7 . ? 49.352 44.010 4.540 1.00 20.11 ? 2285 HOH A O 1 HETATM 8834 O O . HOH G 7 . ? 49.978 43.823 7.093 1.00 23.60 ? 2286 HOH A O 1 HETATM 8835 O O . HOH G 7 . ? 49.096 41.665 8.414 1.00 31.30 ? 2287 HOH A O 1 HETATM 8836 O O . HOH G 7 . ? 51.414 44.988 9.919 1.00 34.86 ? 2288 HOH A O 1 HETATM 8837 O O . HOH G 7 . ? 52.051 50.389 6.371 1.00 15.32 ? 2289 HOH A O 1 HETATM 8838 O O . HOH G 7 . ? 47.457 45.811 3.729 1.00 14.79 ? 2290 HOH A O 1 HETATM 8839 O O . HOH G 7 . ? 38.815 52.796 2.191 1.00 28.28 ? 2291 HOH A O 1 HETATM 8840 O O . HOH G 7 . ? 39.607 55.501 3.040 1.00 18.23 ? 2292 HOH A O 1 HETATM 8841 O O . HOH G 7 . ? 37.492 56.784 1.755 1.00 13.14 ? 2293 HOH A O 1 HETATM 8842 O O . HOH G 7 . ? 35.885 52.860 1.389 1.00 14.35 ? 2294 HOH A O 1 HETATM 8843 O O . HOH G 7 . ? 34.180 52.211 -0.894 1.00 12.73 ? 2295 HOH A O 1 HETATM 8844 O O . HOH G 7 . ? 36.697 51.410 3.908 1.00 15.33 ? 2296 HOH A O 1 HETATM 8845 O O . HOH G 7 . ? 40.090 56.025 5.793 1.00 16.99 ? 2297 HOH A O 1 HETATM 8846 O O . HOH G 7 . ? 42.916 56.568 6.230 1.00 15.72 ? 2298 HOH A O 1 HETATM 8847 O O . HOH G 7 . ? 42.720 56.249 2.818 1.00 22.87 ? 2299 HOH A O 1 HETATM 8848 O O . HOH G 7 . ? 40.166 62.553 6.068 1.00 13.63 ? 2300 HOH A O 1 HETATM 8849 O O . HOH G 7 . ? 38.654 62.124 8.429 1.00 14.83 ? 2301 HOH A O 1 HETATM 8850 O O . HOH G 7 . ? 37.689 58.883 11.098 1.00 14.34 ? 2302 HOH A O 1 HETATM 8851 O O . HOH G 7 . ? 36.839 57.473 13.365 1.00 13.42 ? 2303 HOH A O 1 HETATM 8852 O O . HOH G 7 . ? 39.278 57.203 14.805 1.00 12.92 ? 2304 HOH A O 1 HETATM 8853 O O . HOH G 7 . ? 41.171 58.803 13.535 1.00 14.70 ? 2305 HOH A O 1 HETATM 8854 O O . HOH G 7 . ? 34.281 67.452 12.425 1.00 16.15 ? 2306 HOH A O 1 HETATM 8855 O O . HOH G 7 . ? 34.674 70.105 13.101 1.00 20.99 ? 2307 HOH A O 1 HETATM 8856 O O . HOH G 7 . ? 31.829 70.917 13.544 1.00 28.36 ? 2308 HOH A O 1 HETATM 8857 O O . HOH G 7 . ? 29.824 71.922 12.379 1.00 31.41 ? 2309 HOH A O 1 HETATM 8858 O O . HOH G 7 . ? 29.685 75.329 10.844 1.00 35.42 ? 2310 HOH A O 1 HETATM 8859 O O . HOH G 7 . ? 26.399 74.798 10.960 1.00 33.09 ? 2311 HOH A O 1 HETATM 8860 O O . HOH G 7 . ? 25.244 73.498 8.877 1.00 30.79 ? 2312 HOH A O 1 HETATM 8861 O O . HOH G 7 . ? 26.182 72.418 5.603 1.00 17.87 ? 2313 HOH A O 1 HETATM 8862 O O . HOH G 7 . ? 26.306 75.390 1.671 1.00 32.04 ? 2314 HOH A O 1 HETATM 8863 O O . HOH G 7 . ? 21.380 78.177 -1.384 1.00 23.61 ? 2315 HOH A O 1 HETATM 8864 O O . HOH G 7 . ? 16.470 79.953 -1.270 1.00 46.12 ? 2316 HOH A O 1 HETATM 8865 O O . HOH G 7 . ? 16.886 74.269 -2.912 1.00 21.60 ? 2317 HOH A O 1 HETATM 8866 O O . HOH G 7 . ? 20.127 74.045 -6.702 1.00 17.78 ? 2318 HOH A O 1 HETATM 8867 O O . HOH G 7 . ? 24.615 70.273 -8.681 1.00 16.78 ? 2319 HOH A O 1 HETATM 8868 O O . HOH G 7 . ? 26.756 68.637 -9.204 1.00 13.48 ? 2320 HOH A O 1 HETATM 8869 O O . HOH G 7 . ? 32.634 64.298 -9.957 1.00 21.13 ? 2321 HOH A O 1 HETATM 8870 O O . HOH G 7 . ? 34.210 58.325 -8.696 1.00 12.15 ? 2322 HOH A O 1 HETATM 8871 O O . HOH G 7 . ? 30.157 58.182 -11.716 1.00 12.69 ? 2323 HOH A O 1 HETATM 8872 O O . HOH G 7 . ? 26.756 60.612 -3.255 1.00 13.31 ? 2324 HOH A O 1 HETATM 8873 O O . HOH G 7 . ? 32.516 59.843 -1.747 1.00 12.97 ? 2325 HOH A O 1 HETATM 8874 O O . HOH G 7 . ? 33.061 62.480 0.123 1.00 11.93 ? 2326 HOH A O 1 HETATM 8875 O O . HOH G 7 . ? 30.836 57.021 4.544 1.00 25.84 ? 2327 HOH A O 1 HETATM 8876 O O . HOH G 7 . ? 27.211 59.063 8.546 1.00 20.30 ? 2328 HOH A O 1 HETATM 8877 O O . HOH G 7 . ? 26.945 61.102 10.367 1.00 34.29 ? 2329 HOH A O 1 HETATM 8878 O O . HOH G 7 . ? 24.580 61.173 9.286 1.00 24.31 ? 2330 HOH A O 1 HETATM 8879 O O . HOH G 7 . ? 24.157 63.144 7.490 1.00 17.92 ? 2331 HOH A O 1 HETATM 8880 O O . HOH G 7 . ? 26.003 64.909 8.331 1.00 29.22 ? 2332 HOH A O 1 HETATM 8881 O O . HOH G 7 . ? 27.976 66.320 7.280 1.00 26.22 ? 2333 HOH A O 1 HETATM 8882 O O . HOH G 7 . ? 20.832 64.987 7.795 1.00 21.38 ? 2334 HOH A O 1 HETATM 8883 O O . HOH G 7 . ? 20.755 67.812 8.559 1.00 24.63 ? 2335 HOH A O 1 HETATM 8884 O O . HOH G 7 . ? 17.892 70.607 6.698 1.00 39.49 ? 2336 HOH A O 1 HETATM 8885 O O . HOH G 7 . ? 15.813 69.936 6.351 1.00 37.13 ? 2337 HOH A O 1 HETATM 8886 O O . HOH G 7 . ? 18.581 69.690 4.270 1.00 21.18 ? 2338 HOH A O 1 HETATM 8887 O O . HOH G 7 . ? 19.208 72.179 3.087 1.00 23.35 ? 2339 HOH A O 1 HETATM 8888 O O . HOH G 7 . ? 17.677 74.146 4.002 1.00 28.75 ? 2340 HOH A O 1 HETATM 8889 O O . HOH G 7 . ? 15.646 73.328 5.489 1.00 35.03 ? 2341 HOH A O 1 HETATM 8890 O O . HOH G 7 . ? 19.196 76.298 4.929 1.00 32.77 ? 2342 HOH A O 1 HETATM 8891 O O . HOH G 7 . ? 21.575 79.442 5.436 1.00 35.37 ? 2343 HOH A O 1 HETATM 8892 O O . HOH G 7 . ? 22.165 76.304 8.861 1.00 34.89 ? 2344 HOH A O 1 HETATM 8893 O O . HOH G 7 . ? 27.461 82.092 3.482 1.00 34.48 ? 2345 HOH A O 1 HETATM 8894 O O . HOH G 7 . ? 29.752 82.792 2.454 1.00 24.85 ? 2346 HOH A O 1 HETATM 8895 O O . HOH G 7 . ? 31.061 82.982 4.797 1.00 38.41 ? 2347 HOH A O 1 HETATM 8896 O O . HOH G 7 . ? 30.255 82.036 7.383 1.00 41.88 ? 2348 HOH A O 1 HETATM 8897 O O . HOH G 7 . ? 32.218 80.171 7.373 1.00 37.52 ? 2349 HOH A O 1 HETATM 8898 O O . HOH G 7 . ? 36.179 80.729 6.374 1.00 23.72 ? 2350 HOH A O 1 HETATM 8899 O O . HOH G 7 . ? 34.877 77.455 12.240 1.00 35.62 ? 2351 HOH A O 1 HETATM 8900 O O . HOH G 7 . ? 35.814 73.256 15.402 1.00 35.07 ? 2352 HOH A O 1 HETATM 8901 O O . HOH G 7 . ? 35.605 70.395 16.191 1.00 46.99 ? 2353 HOH A O 1 HETATM 8902 O O . HOH G 7 . ? 36.004 70.034 19.291 1.00 41.35 ? 2354 HOH A O 1 HETATM 8903 O O . HOH G 7 . ? 36.028 67.905 20.589 1.00 44.65 ? 2355 HOH A O 1 HETATM 8904 O O . HOH G 7 . ? 35.798 68.204 23.378 1.00 33.19 ? 2356 HOH A O 1 HETATM 8905 O O . HOH G 7 . ? 32.573 69.219 24.474 1.00 27.20 ? 2357 HOH A O 1 HETATM 8906 O O . HOH G 7 . ? 30.925 70.714 21.511 1.00 40.91 ? 2358 HOH A O 1 HETATM 8907 O O . HOH G 7 . ? 28.684 72.312 22.433 1.00 30.58 ? 2359 HOH A O 1 HETATM 8908 O O . HOH G 7 . ? 29.536 74.841 22.228 1.00 29.33 ? 2360 HOH A O 1 HETATM 8909 O O . HOH G 7 . ? 25.003 70.986 22.655 1.00 40.63 ? 2361 HOH A O 1 HETATM 8910 O O . HOH G 7 . ? 24.738 68.080 21.797 1.00 26.23 ? 2362 HOH A O 1 HETATM 8911 O O . HOH G 7 . ? 22.364 67.927 20.436 1.00 27.93 ? 2363 HOH A O 1 HETATM 8912 O O . HOH G 7 . ? 20.437 68.154 22.263 1.00 30.24 ? 2364 HOH A O 1 HETATM 8913 O O . HOH G 7 . ? 20.725 65.225 27.466 1.00 29.96 ? 2365 HOH A O 1 HETATM 8914 O O . HOH G 7 . ? 22.519 65.836 29.353 1.00 34.28 ? 2366 HOH A O 1 HETATM 8915 O O . HOH G 7 . ? 22.061 65.492 32.387 1.00 32.90 ? 2367 HOH A O 1 HETATM 8916 O O . HOH G 7 . ? 22.178 62.657 33.649 1.00 32.58 ? 2368 HOH A O 1 HETATM 8917 O O . HOH G 7 . ? 24.275 60.809 36.226 1.00 37.26 ? 2369 HOH A O 1 HETATM 8918 O O . HOH G 7 . ? 23.977 57.323 38.597 1.00 38.88 ? 2370 HOH A O 1 HETATM 8919 O O . HOH G 7 . ? 21.556 55.325 40.203 1.00 31.59 ? 2371 HOH A O 1 HETATM 8920 O O . HOH G 7 . ? 17.772 52.649 35.889 1.00 41.34 ? 2372 HOH A O 1 HETATM 8921 O O . HOH G 7 . ? 17.421 52.425 33.322 1.00 46.31 ? 2373 HOH A O 1 HETATM 8922 O O . HOH G 7 . ? 18.838 48.604 37.733 1.00 25.46 ? 2374 HOH A O 1 HETATM 8923 O O . HOH G 7 . ? 21.333 47.187 39.177 1.00 26.31 ? 2375 HOH A O 1 HETATM 8924 O O . HOH G 7 . ? 24.185 45.497 40.979 1.00 38.70 ? 2376 HOH A O 1 HETATM 8925 O O . HOH G 7 . ? 28.210 44.387 38.292 1.00 33.49 ? 2377 HOH A O 1 HETATM 8926 O O . HOH G 7 . ? 29.152 46.892 37.196 1.00 27.34 ? 2378 HOH A O 1 HETATM 8927 O O . HOH G 7 . ? 31.692 47.248 38.058 1.00 38.57 ? 2379 HOH A O 1 HETATM 8928 O O . HOH G 7 . ? 34.164 47.863 36.563 1.00 38.58 ? 2380 HOH A O 1 HETATM 8929 O O . HOH G 7 . ? 34.993 51.011 35.977 1.00 38.34 ? 2381 HOH A O 1 HETATM 8930 O O . HOH G 7 . ? 39.462 49.782 36.342 1.00 34.71 ? 2382 HOH A O 1 HETATM 8931 O O . HOH G 7 . ? 40.138 52.510 36.358 1.00 34.74 ? 2383 HOH A O 1 HETATM 8932 O O . HOH G 7 . ? 42.701 53.222 35.565 1.00 25.18 ? 2384 HOH A O 1 HETATM 8933 O O . HOH G 7 . ? 44.823 55.153 36.076 1.00 40.90 ? 2385 HOH A O 1 HETATM 8934 O O . HOH G 7 . ? 43.527 56.544 33.657 1.00 33.30 ? 2386 HOH A O 1 HETATM 8935 O O . HOH G 7 . ? 41.853 58.217 34.653 1.00 36.64 ? 2387 HOH A O 1 HETATM 8936 O O . HOH G 7 . ? 40.632 57.012 30.966 1.00 28.13 ? 2388 HOH A O 1 HETATM 8937 O O . HOH G 7 . ? 45.621 58.077 32.734 1.00 42.55 ? 2389 HOH A O 1 HETATM 8938 O O . HOH G 7 . ? 50.803 55.587 34.745 1.00 49.21 ? 2390 HOH A O 1 HETATM 8939 O O . HOH G 7 . ? 49.571 50.598 32.631 1.00 31.18 ? 2391 HOH A O 1 HETATM 8940 O O . HOH G 7 . ? 49.062 49.723 28.342 1.00 20.86 ? 2392 HOH A O 1 HETATM 8941 O O . HOH G 7 . ? 49.737 47.021 28.923 1.00 30.17 ? 2393 HOH A O 1 HETATM 8942 O O . HOH G 7 . ? 49.481 45.431 30.964 1.00 35.45 ? 2394 HOH A O 1 HETATM 8943 O O . HOH G 7 . ? 47.414 43.493 30.619 1.00 45.26 ? 2395 HOH A O 1 HETATM 8944 O O . HOH G 7 . ? 42.122 48.632 31.280 1.00 23.13 ? 2396 HOH A O 1 HETATM 8945 O O . HOH G 7 . ? 41.124 50.267 33.202 1.00 23.68 ? 2397 HOH A O 1 HETATM 8946 O O . HOH G 7 . ? 39.379 49.121 30.117 1.00 23.18 ? 2398 HOH A O 1 HETATM 8947 O O . HOH G 7 . ? 37.525 47.109 29.804 1.00 22.50 ? 2399 HOH A O 1 HETATM 8948 O O . HOH G 7 . ? 35.973 45.112 30.938 1.00 22.56 ? 2400 HOH A O 1 HETATM 8949 O O . HOH G 7 . ? 35.137 43.611 28.735 1.00 18.08 ? 2401 HOH A O 1 HETATM 8950 O O . HOH G 7 . ? 37.066 45.473 27.503 1.00 17.80 ? 2402 HOH A O 1 HETATM 8951 O O . HOH G 7 . ? 38.907 42.851 22.800 1.00 31.05 ? 2403 HOH A O 1 HETATM 8952 O O . HOH G 7 . ? 34.761 45.756 33.381 1.00 22.50 ? 2404 HOH A O 1 HETATM 8953 O O . HOH G 7 . ? 30.825 43.770 40.697 1.00 45.95 ? 2405 HOH A O 1 HETATM 8954 O O . HOH G 7 . ? 28.120 49.277 38.530 1.00 31.86 ? 2406 HOH A O 1 HETATM 8955 O O . HOH G 7 . ? 30.575 51.402 39.634 1.00 48.02 ? 2407 HOH A O 1 HETATM 8956 O O . HOH G 7 . ? 28.877 55.018 40.053 1.00 32.17 ? 2408 HOH A O 1 HETATM 8957 O O . HOH G 7 . ? 30.442 57.358 40.064 1.00 36.02 ? 2409 HOH A O 1 HETATM 8958 O O . HOH G 7 . ? 31.534 57.401 37.353 1.00 29.87 ? 2410 HOH A O 1 HETATM 8959 O O . HOH G 7 . ? 30.147 59.159 35.312 1.00 32.04 ? 2411 HOH A O 1 HETATM 8960 O O . HOH G 7 . ? 35.265 62.194 33.992 1.00 31.84 ? 2412 HOH A O 1 HETATM 8961 O O . HOH G 7 . ? 37.645 62.192 35.635 1.00 34.98 ? 2413 HOH A O 1 HETATM 8962 O O . HOH G 7 . ? 39.842 66.898 31.270 1.00 27.83 ? 2414 HOH A O 1 HETATM 8963 O O . HOH G 7 . ? 42.009 67.231 29.262 1.00 31.25 ? 2415 HOH A O 1 HETATM 8964 O O . HOH G 7 . ? 44.599 67.768 28.142 1.00 39.94 ? 2416 HOH A O 1 HETATM 8965 O O . HOH G 7 . ? 46.379 68.319 26.472 1.00 36.04 ? 2417 HOH A O 1 HETATM 8966 O O . HOH G 7 . ? 47.677 65.928 26.937 1.00 29.32 ? 2418 HOH A O 1 HETATM 8967 O O . HOH G 7 . ? 50.783 61.715 26.403 1.00 26.97 ? 2419 HOH A O 1 HETATM 8968 O O . HOH G 7 . ? 51.865 59.996 28.169 1.00 34.95 ? 2420 HOH A O 1 HETATM 8969 O O . HOH G 7 . ? 51.787 63.628 24.503 1.00 32.58 ? 2421 HOH A O 1 HETATM 8970 O O . HOH G 7 . ? 52.705 67.241 22.458 1.00 46.98 ? 2422 HOH A O 1 HETATM 8971 O O . HOH G 7 . ? 50.841 69.478 24.353 1.00 46.32 ? 2423 HOH A O 1 HETATM 8972 O O . HOH G 7 . ? 51.899 71.401 22.326 1.00 41.86 ? 2424 HOH A O 1 HETATM 8973 O O . HOH G 7 . ? 52.488 72.328 18.290 1.00 31.01 ? 2425 HOH A O 1 HETATM 8974 O O . HOH G 7 . ? 53.026 69.464 18.217 1.00 28.22 ? 2426 HOH A O 1 HETATM 8975 O O . HOH G 7 . ? 55.999 70.798 19.701 1.00 47.08 ? 2427 HOH A O 1 HETATM 8976 O O . HOH G 7 . ? 57.854 67.985 13.517 1.00 46.32 ? 2428 HOH A O 1 HETATM 8977 O O . HOH G 7 . ? 55.541 67.293 13.467 1.00 36.16 ? 2429 HOH A O 1 HETATM 8978 O O . HOH G 7 . ? 60.703 63.351 15.372 1.00 43.39 ? 2430 HOH A O 1 HETATM 8979 O O . HOH G 7 . ? 62.115 64.003 13.702 1.00 41.66 ? 2431 HOH A O 1 HETATM 8980 O O . HOH G 7 . ? 61.502 59.189 14.616 1.00 35.39 ? 2432 HOH A O 1 HETATM 8981 O O . HOH G 7 . ? 61.094 56.930 15.453 1.00 41.15 ? 2433 HOH A O 1 HETATM 8982 O O . HOH G 7 . ? 58.744 50.829 14.788 1.00 41.96 ? 2434 HOH A O 1 HETATM 8983 O O . HOH G 7 . ? 57.543 49.088 16.702 1.00 37.68 ? 2435 HOH A O 1 HETATM 8984 O O . HOH G 7 . ? 55.227 50.026 16.918 1.00 31.33 ? 2436 HOH A O 1 HETATM 8985 O O . HOH G 7 . ? 54.194 47.470 15.636 1.00 31.11 ? 2437 HOH A O 1 HETATM 8986 O O . HOH G 7 . ? 56.723 46.360 15.956 1.00 39.00 ? 2438 HOH A O 1 HETATM 8987 O O . HOH G 7 . ? 57.320 48.737 21.525 1.00 30.84 ? 2439 HOH A O 1 HETATM 8988 O O . HOH G 7 . ? 58.654 50.941 22.160 1.00 27.56 ? 2440 HOH A O 1 HETATM 8989 O O . HOH G 7 . ? 60.174 50.587 20.344 1.00 37.80 ? 2441 HOH A O 1 HETATM 8990 O O . HOH G 7 . ? 59.472 50.618 24.787 1.00 40.13 ? 2442 HOH A O 1 HETATM 8991 O O . HOH G 7 . ? 57.911 52.559 26.321 1.00 45.55 ? 2443 HOH A O 1 HETATM 8992 O O . HOH G 7 . ? 55.820 51.624 27.362 1.00 35.57 ? 2444 HOH A O 1 HETATM 8993 O O . HOH G 7 . ? 53.111 52.437 26.334 1.00 35.03 ? 2445 HOH A O 1 HETATM 8994 O O . HOH G 7 . ? 51.812 50.228 27.447 1.00 33.32 ? 2446 HOH A O 1 HETATM 8995 O O . HOH G 7 . ? 52.368 48.936 25.635 1.00 38.05 ? 2447 HOH A O 1 HETATM 8996 O O . HOH G 7 . ? 53.885 46.631 23.461 1.00 36.83 ? 2448 HOH A O 1 HETATM 8997 O O . HOH G 7 . ? 53.125 44.279 23.056 1.00 45.00 ? 2449 HOH A O 1 HETATM 8998 O O . HOH G 7 . ? 59.252 55.326 27.072 1.00 43.31 ? 2450 HOH A O 1 HETATM 8999 O O . HOH G 7 . ? 59.422 61.998 25.785 1.00 37.03 ? 2451 HOH A O 1 HETATM 9000 O O . HOH G 7 . ? 62.325 62.022 25.530 1.00 35.41 ? 2452 HOH A O 1 HETATM 9001 O O . HOH G 7 . ? 56.931 64.654 24.163 1.00 32.45 ? 2453 HOH A O 1 HETATM 9002 O O . HOH G 7 . ? 45.781 74.083 22.552 1.00 37.82 ? 2454 HOH A O 1 HETATM 9003 O O . HOH G 7 . ? 38.312 73.466 18.016 1.00 42.42 ? 2455 HOH A O 1 HETATM 9004 O O . HOH G 7 . ? 32.938 66.772 21.286 1.00 28.96 ? 2456 HOH A O 1 HETATM 9005 O O . HOH G 7 . ? 31.831 65.246 18.866 1.00 19.79 ? 2457 HOH A O 1 HETATM 9006 O O . HOH G 7 . ? 29.723 66.831 18.109 1.00 39.29 ? 2458 HOH A O 1 HETATM 9007 O O . HOH G 7 . ? 29.357 65.632 15.919 1.00 43.68 ? 2459 HOH A O 1 HETATM 9008 O O . HOH G 7 . ? 28.145 63.983 14.606 1.00 45.76 ? 2460 HOH A O 1 HETATM 9009 O O . HOH G 7 . ? 25.648 62.854 13.664 1.00 30.55 ? 2461 HOH A O 1 HETATM 9010 O O . HOH G 7 . ? 26.245 63.468 17.126 1.00 21.77 ? 2462 HOH A O 1 HETATM 9011 O O . HOH G 7 . ? 25.558 65.805 17.239 1.00 31.82 ? 2463 HOH A O 1 HETATM 9012 O O . HOH G 7 . ? 26.359 66.579 19.812 1.00 32.41 ? 2464 HOH A O 1 HETATM 9013 O O . HOH G 7 . ? 28.603 65.017 19.680 1.00 20.20 ? 2465 HOH A O 1 HETATM 9014 O O . HOH G 7 . ? 27.921 60.834 19.492 1.00 16.11 ? 2466 HOH A O 1 HETATM 9015 O O . HOH G 7 . ? 23.101 64.182 18.387 1.00 36.31 ? 2467 HOH A O 1 HETATM 9016 O O . HOH G 7 . ? 22.598 62.294 16.256 1.00 25.24 ? 2468 HOH A O 1 HETATM 9017 O O . HOH G 7 . ? 21.540 63.390 14.438 1.00 40.66 ? 2469 HOH A O 1 HETATM 9018 O O . HOH G 7 . ? 15.463 60.066 15.604 1.00 19.79 ? 2470 HOH A O 1 HETATM 9019 O O . HOH G 7 . ? 13.969 58.009 16.441 1.00 19.62 ? 2471 HOH A O 1 HETATM 9020 O O . HOH G 7 . ? 13.965 57.393 19.133 1.00 23.36 ? 2472 HOH A O 1 HETATM 9021 O O . HOH G 7 . ? 11.650 58.181 20.187 1.00 34.80 ? 2473 HOH A O 1 HETATM 9022 O O . HOH G 7 . ? 12.363 55.011 22.696 1.00 29.49 ? 2474 HOH A O 1 HETATM 9023 O O . HOH G 7 . ? 12.879 54.769 25.380 1.00 34.76 ? 2475 HOH A O 1 HETATM 9024 O O . HOH G 7 . ? 13.267 52.186 25.961 1.00 36.28 ? 2476 HOH A O 1 HETATM 9025 O O . HOH G 7 . ? 14.111 50.248 24.318 1.00 28.84 ? 2477 HOH A O 1 HETATM 9026 O O . HOH G 7 . ? 13.441 51.271 21.844 1.00 22.95 ? 2478 HOH A O 1 HETATM 9027 O O . HOH G 7 . ? 10.793 51.153 21.487 1.00 32.30 ? 2479 HOH A O 1 HETATM 9028 O O . HOH G 7 . ? 10.309 50.504 19.047 1.00 28.90 ? 2480 HOH A O 1 HETATM 9029 O O . HOH G 7 . ? 9.365 52.186 17.032 1.00 25.28 ? 2481 HOH A O 1 HETATM 9030 O O . HOH G 7 . ? 7.714 54.447 17.439 1.00 37.58 ? 2482 HOH A O 1 HETATM 9031 O O . HOH G 7 . ? 9.858 53.465 22.171 1.00 37.15 ? 2483 HOH A O 1 HETATM 9032 O O . HOH G 7 . ? 12.115 48.716 25.490 1.00 46.84 ? 2484 HOH A O 1 HETATM 9033 O O . HOH G 7 . ? 14.267 47.321 26.912 1.00 44.66 ? 2485 HOH A O 1 HETATM 9034 O O . HOH G 7 . ? 13.842 45.001 27.236 1.00 42.09 ? 2486 HOH A O 1 HETATM 9035 O O . HOH G 7 . ? 12.795 44.098 22.829 1.00 45.27 ? 2487 HOH A O 1 HETATM 9036 O O . HOH G 7 . ? 11.142 46.581 21.741 1.00 45.90 ? 2488 HOH A O 1 HETATM 9037 O O . HOH G 7 . ? 11.521 46.702 17.968 1.00 27.10 ? 2489 HOH A O 1 HETATM 9038 O O . HOH G 7 . ? 12.597 49.306 17.914 1.00 24.96 ? 2490 HOH A O 1 HETATM 9039 O O . HOH G 7 . ? 14.366 49.490 19.964 1.00 22.36 ? 2491 HOH A O 1 HETATM 9040 O O . HOH G 7 . ? 14.025 48.896 15.487 1.00 20.49 ? 2492 HOH A O 1 HETATM 9041 O O . HOH G 7 . ? 11.766 51.305 14.456 1.00 20.72 ? 2493 HOH A O 1 HETATM 9042 O O . HOH G 7 . ? 8.047 47.764 11.971 1.00 28.81 ? 2494 HOH A O 1 HETATM 9043 O O . HOH G 7 . ? 8.720 44.256 13.329 1.00 34.19 ? 2495 HOH A O 1 HETATM 9044 O O . HOH G 7 . ? 10.344 41.324 12.302 1.00 38.58 ? 2496 HOH A O 1 HETATM 9045 O O . HOH G 7 . ? 12.926 42.295 12.783 1.00 24.35 ? 2497 HOH A O 1 HETATM 9046 O O . HOH G 7 . ? 17.269 41.425 9.325 1.00 33.55 ? 2498 HOH A O 1 HETATM 9047 O O . HOH G 7 . ? 20.489 37.619 12.287 1.00 35.60 ? 2499 HOH A O 1 HETATM 9048 O O . HOH G 7 . ? 23.012 36.872 13.564 1.00 34.30 ? 2500 HOH A O 1 HETATM 9049 O O . HOH G 7 . ? 21.767 37.699 15.742 1.00 41.85 ? 2501 HOH A O 1 HETATM 9050 O O . HOH G 7 . ? 19.665 39.060 17.714 1.00 20.67 ? 2502 HOH A O 1 HETATM 9051 O O . HOH G 7 . ? 15.999 36.068 16.279 1.00 33.04 ? 2503 HOH A O 1 HETATM 9052 O O . HOH G 7 . ? 16.149 33.406 15.849 1.00 42.79 ? 2504 HOH A O 1 HETATM 9053 O O . HOH G 7 . ? 15.891 30.688 18.113 1.00 47.58 ? 2505 HOH A O 1 HETATM 9054 O O . HOH G 7 . ? 24.185 34.405 15.835 1.00 37.43 ? 2506 HOH A O 1 HETATM 9055 O O . HOH G 7 . ? 25.236 33.163 13.452 1.00 37.73 ? 2507 HOH A O 1 HETATM 9056 O O . HOH G 7 . ? 24.295 32.929 9.746 1.00 34.63 ? 2508 HOH A O 1 HETATM 9057 O O . HOH G 7 . ? 24.750 32.815 6.594 1.00 30.38 ? 2509 HOH A O 1 HETATM 9058 O O . HOH G 7 . ? 30.547 29.524 6.122 1.00 46.58 ? 2510 HOH A O 1 HETATM 9059 O O . HOH G 7 . ? 31.056 33.300 2.932 1.00 26.91 ? 2511 HOH A O 1 HETATM 9060 O O . HOH G 7 . ? 25.878 39.533 5.350 1.00 14.12 ? 2512 HOH A O 1 HETATM 9061 O O . HOH G 7 . ? 26.253 39.900 8.042 1.00 15.99 ? 2513 HOH A O 1 HETATM 9062 O O . HOH G 7 . ? 23.983 41.774 7.021 1.00 14.78 ? 2514 HOH A O 1 HETATM 9063 O O . HOH G 7 . ? 28.141 39.499 11.379 1.00 16.58 ? 2515 HOH A O 1 HETATM 9064 O O . HOH G 7 . ? 27.224 41.209 13.422 1.00 20.17 ? 2516 HOH A O 1 HETATM 9065 O O . HOH G 7 . ? 28.207 43.698 13.285 1.00 13.73 ? 2517 HOH A O 1 HETATM 9066 O O . HOH G 7 . ? 27.193 46.186 13.715 1.00 18.90 ? 2518 HOH A O 1 HETATM 9067 O O . HOH G 7 . ? 27.875 48.359 12.161 1.00 18.52 ? 2519 HOH A O 1 HETATM 9068 O O . HOH G 7 . ? 27.556 50.722 13.351 1.00 22.69 ? 2520 HOH A O 1 HETATM 9069 O O . HOH G 7 . ? 25.637 51.980 12.990 1.00 26.43 ? 2521 HOH A O 1 HETATM 9070 O O . HOH G 7 . ? 25.423 53.498 11.143 1.00 17.69 ? 2522 HOH A O 1 HETATM 9071 O O . HOH G 7 . ? 19.288 55.011 11.614 1.00 17.15 ? 2523 HOH A O 1 HETATM 9072 O O . HOH G 7 . ? 17.014 55.984 10.382 1.00 16.59 ? 2524 HOH A O 1 HETATM 9073 O O . HOH G 7 . ? 16.712 56.812 13.068 1.00 20.02 ? 2525 HOH A O 1 HETATM 9074 O O . HOH G 7 . ? 18.339 54.736 14.214 1.00 17.47 ? 2526 HOH A O 1 HETATM 9075 O O . HOH G 7 . ? 20.043 54.543 16.236 1.00 14.74 ? 2527 HOH A O 1 HETATM 9076 O O . HOH G 7 . ? 19.221 53.336 8.235 1.00 15.70 ? 2528 HOH A O 1 HETATM 9077 O O . HOH G 7 . ? 17.539 52.586 6.411 1.00 15.79 ? 2529 HOH A O 1 HETATM 9078 O O . HOH G 7 . ? 20.015 55.829 7.250 1.00 16.93 ? 2530 HOH A O 1 HETATM 9079 O O . HOH G 7 . ? 21.643 56.860 5.089 1.00 15.70 ? 2531 HOH A O 1 HETATM 9080 O O . HOH G 7 . ? 23.757 57.903 6.389 1.00 15.30 ? 2532 HOH A O 1 HETATM 9081 O O . HOH G 7 . ? 14.402 59.800 5.269 1.00 18.96 ? 2533 HOH A O 1 HETATM 9082 O O . HOH G 7 . ? 13.646 60.471 7.732 1.00 35.05 ? 2534 HOH A O 1 HETATM 9083 O O . HOH G 7 . ? 11.611 58.512 8.001 1.00 28.36 ? 2535 HOH A O 1 HETATM 9084 O O . HOH G 7 . ? 9.817 59.479 6.569 1.00 40.17 ? 2536 HOH A O 1 HETATM 9085 O O . HOH G 7 . ? 11.385 61.894 5.489 1.00 35.70 ? 2537 HOH A O 1 HETATM 9086 O O . HOH G 7 . ? 10.303 61.938 2.022 1.00 37.28 ? 2538 HOH A O 1 HETATM 9087 O O . HOH G 7 . ? 11.675 61.467 0.145 1.00 44.40 ? 2539 HOH A O 1 HETATM 9088 O O . HOH G 7 . ? 12.895 61.752 -2.253 1.00 28.85 ? 2540 HOH A O 1 HETATM 9089 O O . HOH G 7 . ? 14.038 59.487 -3.287 1.00 19.20 ? 2541 HOH A O 1 HETATM 9090 O O . HOH G 7 . ? 13.886 57.715 -1.264 1.00 23.57 ? 2542 HOH A O 1 HETATM 9091 O O . HOH G 7 . ? 10.019 57.873 -2.983 1.00 33.42 ? 2543 HOH A O 1 HETATM 9092 O O . HOH G 7 . ? 11.731 59.237 -4.876 1.00 24.65 ? 2544 HOH A O 1 HETATM 9093 O O . HOH G 7 . ? 11.039 62.235 -4.353 1.00 45.73 ? 2545 HOH A O 1 HETATM 9094 O O . HOH G 7 . ? 13.152 66.537 -4.709 1.00 19.90 ? 2546 HOH A O 1 HETATM 9095 O O . HOH G 7 . ? 14.105 67.950 -7.626 1.00 23.86 ? 2547 HOH A O 1 HETATM 9096 O O . HOH G 7 . ? 13.710 69.879 -9.531 1.00 28.11 ? 2548 HOH A O 1 HETATM 9097 O O . HOH G 7 . ? 11.560 70.672 -7.543 1.00 39.36 ? 2549 HOH A O 1 HETATM 9098 O O . HOH G 7 . ? 12.659 66.085 -9.557 1.00 24.00 ? 2550 HOH A O 1 HETATM 9099 O O . HOH G 7 . ? 10.274 64.315 -10.124 1.00 38.75 ? 2551 HOH A O 1 HETATM 9100 O O . HOH G 7 . ? 8.727 65.862 -11.926 1.00 38.83 ? 2552 HOH A O 1 HETATM 9101 O O . HOH G 7 . ? 8.505 64.943 -14.623 1.00 30.18 ? 2553 HOH A O 1 HETATM 9102 O O . HOH G 7 . ? 16.450 67.592 -19.710 1.00 25.61 ? 2554 HOH A O 1 HETATM 9103 O O . HOH G 7 . ? 16.111 71.750 -18.827 1.00 24.97 ? 2555 HOH A O 1 HETATM 9104 O O . HOH G 7 . ? 17.050 70.027 -16.196 1.00 17.77 ? 2556 HOH A O 1 HETATM 9105 O O . HOH G 7 . ? 20.500 65.920 -19.520 1.00 17.01 ? 2557 HOH A O 1 HETATM 9106 O O . HOH G 7 . ? 20.257 58.503 -21.839 1.00 14.69 ? 2558 HOH A O 1 HETATM 9107 O O . HOH G 7 . ? 16.646 60.300 -27.968 1.00 27.36 ? 2559 HOH A O 1 HETATM 9108 O O . HOH G 7 . ? 14.520 54.935 -26.136 1.00 36.07 ? 2560 HOH A O 1 HETATM 9109 O O . HOH G 7 . ? 19.182 52.383 -26.735 1.00 33.34 ? 2561 HOH A O 1 HETATM 9110 O O . HOH G 7 . ? 19.133 51.889 -31.123 1.00 40.74 ? 2562 HOH A O 1 HETATM 9111 O O . HOH G 7 . ? 18.429 51.863 -37.185 1.00 40.08 ? 2563 HOH A O 1 HETATM 9112 O O . HOH G 7 . ? 20.729 50.789 -38.193 1.00 36.17 ? 2564 HOH A O 1 HETATM 9113 O O . HOH G 7 . ? 22.831 48.639 -36.106 1.00 35.89 ? 2565 HOH A O 1 HETATM 9114 O O . HOH G 7 . ? 21.301 55.105 -36.201 1.00 38.62 ? 2566 HOH A O 1 HETATM 9115 O O . HOH G 7 . ? 22.442 56.513 -34.077 1.00 21.92 ? 2567 HOH A O 1 HETATM 9116 O O . HOH G 7 . ? 20.763 58.661 -34.410 1.00 23.64 ? 2568 HOH A O 1 HETATM 9117 O O . HOH G 7 . ? 19.486 58.197 -36.644 1.00 28.44 ? 2569 HOH A O 1 HETATM 9118 O O . HOH G 7 . ? 18.699 60.388 -37.720 1.00 29.68 ? 2570 HOH A O 1 HETATM 9119 O O . HOH G 7 . ? 20.718 60.508 -40.181 1.00 36.89 ? 2571 HOH A O 1 HETATM 9120 O O . HOH G 7 . ? 25.577 58.545 -38.613 1.00 46.96 ? 2572 HOH A O 1 HETATM 9121 O O . HOH G 7 . ? 24.834 59.055 -36.180 1.00 45.06 ? 2573 HOH A O 1 HETATM 9122 O O . HOH G 7 . ? 21.745 61.090 -34.639 1.00 33.22 ? 2574 HOH A O 1 HETATM 9123 O O . HOH G 7 . ? 22.387 63.030 -32.914 1.00 26.05 ? 2575 HOH A O 1 HETATM 9124 O O . HOH G 7 . ? 18.578 70.363 -29.931 1.00 41.72 ? 2576 HOH A O 1 HETATM 9125 O O . HOH G 7 . ? 18.326 75.962 -29.336 1.00 44.91 ? 2577 HOH A O 1 HETATM 9126 O O . HOH G 7 . ? 22.901 78.244 -30.239 1.00 30.19 ? 2578 HOH A O 1 HETATM 9127 O O . HOH G 7 . ? 20.548 79.909 -33.311 1.00 45.24 ? 2579 HOH A O 1 HETATM 9128 O O . HOH G 7 . ? 22.107 79.644 -35.928 1.00 32.11 ? 2580 HOH A O 1 HETATM 9129 O O . HOH G 7 . ? 19.418 82.833 -34.334 1.00 48.67 ? 2581 HOH A O 1 HETATM 9130 O O . HOH G 7 . ? 23.254 82.207 -40.440 1.00 31.27 ? 2582 HOH A O 1 HETATM 9131 O O . HOH G 7 . ? 25.916 87.308 -42.897 1.00 46.32 ? 2583 HOH A O 1 HETATM 9132 O O . HOH G 7 . ? 28.322 87.370 -41.596 1.00 37.28 ? 2584 HOH A O 1 HETATM 9133 O O . HOH G 7 . ? 28.340 90.166 -42.771 1.00 34.53 ? 2585 HOH A O 1 HETATM 9134 O O . HOH G 7 . ? 32.560 88.661 -43.246 1.00 28.74 ? 2586 HOH A O 1 HETATM 9135 O O . HOH G 7 . ? 33.985 86.403 -43.521 1.00 44.81 ? 2587 HOH A O 1 HETATM 9136 O O . HOH G 7 . ? 32.757 89.748 -45.732 1.00 38.81 ? 2588 HOH A O 1 HETATM 9137 O O . HOH G 7 . ? 38.629 93.508 -42.326 1.00 29.62 ? 2589 HOH A O 1 HETATM 9138 O O . HOH G 7 . ? 42.047 87.283 -41.014 1.00 20.48 ? 2590 HOH A O 1 HETATM 9139 O O . HOH G 7 . ? 43.624 87.983 -38.629 1.00 21.00 ? 2591 HOH A O 1 HETATM 9140 O O . HOH G 7 . ? 38.931 85.999 -41.501 1.00 35.41 ? 2592 HOH A O 1 HETATM 9141 O O . HOH G 7 . ? 38.673 83.016 -39.697 1.00 28.29 ? 2593 HOH A O 1 HETATM 9142 O O . HOH G 7 . ? 37.012 81.990 -41.369 1.00 42.15 ? 2594 HOH A O 1 HETATM 9143 O O . HOH G 7 . ? 35.774 76.865 -43.068 1.00 38.50 ? 2595 HOH A O 1 HETATM 9144 O O . HOH G 7 . ? 37.695 75.169 -42.151 1.00 28.86 ? 2596 HOH A O 1 HETATM 9145 O O . HOH G 7 . ? 39.639 75.186 -40.202 1.00 22.96 ? 2597 HOH A O 1 HETATM 9146 O O . HOH G 7 . ? 42.181 74.419 -41.362 1.00 31.70 ? 2598 HOH A O 1 HETATM 9147 O O . HOH G 7 . ? 43.687 72.140 -41.883 1.00 27.51 ? 2599 HOH A O 1 HETATM 9148 O O . HOH G 7 . ? 44.566 71.461 -44.516 1.00 46.26 ? 2600 HOH A O 1 HETATM 9149 O O . HOH G 7 . ? 46.172 69.815 -39.842 1.00 41.89 ? 2601 HOH A O 1 HETATM 9150 O O . HOH G 7 . ? 46.570 69.901 -36.573 1.00 25.13 ? 2602 HOH A O 1 HETATM 9151 O O . HOH G 7 . ? 48.974 68.694 -36.845 1.00 34.72 ? 2603 HOH A O 1 HETATM 9152 O O . HOH G 7 . ? 51.636 69.807 -38.180 1.00 31.76 ? 2604 HOH A O 1 HETATM 9153 O O . HOH G 7 . ? 53.935 70.865 -36.816 1.00 19.70 ? 2605 HOH A O 1 HETATM 9154 O O . HOH G 7 . ? 55.513 68.693 -37.705 1.00 39.36 ? 2606 HOH A O 1 HETATM 9155 O O . HOH G 7 . ? 56.774 69.595 -39.667 1.00 36.83 ? 2607 HOH A O 1 HETATM 9156 O O . HOH G 7 . ? 60.087 68.340 -38.776 1.00 34.11 ? 2608 HOH A O 1 HETATM 9157 O O . HOH G 7 . ? 61.105 67.138 -36.659 1.00 38.16 ? 2609 HOH A O 1 HETATM 9158 O O . HOH G 7 . ? 59.359 66.999 -34.667 1.00 32.81 ? 2610 HOH A O 1 HETATM 9159 O O . HOH G 7 . ? 56.859 67.392 -35.444 1.00 26.18 ? 2611 HOH A O 1 HETATM 9160 O O . HOH G 7 . ? 56.097 64.791 -36.006 1.00 29.02 ? 2612 HOH A O 1 HETATM 9161 O O . HOH G 7 . ? 52.769 58.912 -32.422 1.00 42.81 ? 2613 HOH A O 1 HETATM 9162 O O . HOH G 7 . ? 50.400 60.986 -30.948 1.00 29.72 ? 2614 HOH A O 1 HETATM 9163 O O . HOH G 7 . ? 47.335 57.380 -32.108 1.00 42.44 ? 2615 HOH A O 1 HETATM 9164 O O . HOH G 7 . ? 42.789 56.480 -31.472 1.00 28.35 ? 2616 HOH A O 1 HETATM 9165 O O . HOH G 7 . ? 42.773 59.165 -31.308 1.00 29.73 ? 2617 HOH A O 1 HETATM 9166 O O . HOH G 7 . ? 41.656 60.900 -29.525 1.00 22.33 ? 2618 HOH A O 1 HETATM 9167 O O . HOH G 7 . ? 43.553 62.427 -28.333 1.00 25.72 ? 2619 HOH A O 1 HETATM 9168 O O . HOH G 7 . ? 43.366 63.323 -32.179 1.00 38.20 ? 2620 HOH A O 1 HETATM 9169 O O . HOH G 7 . ? 40.821 62.383 -31.702 1.00 26.02 ? 2621 HOH A O 1 HETATM 9170 O O . HOH G 7 . ? 37.542 61.053 -32.336 1.00 30.24 ? 2622 HOH A O 1 HETATM 9171 O O . HOH G 7 . ? 36.889 58.663 -33.380 1.00 33.10 ? 2623 HOH A O 1 HETATM 9172 O O . HOH G 7 . ? 34.723 59.223 -34.812 1.00 28.53 ? 2624 HOH A O 1 HETATM 9173 O O . HOH G 7 . ? 33.505 56.720 -35.861 1.00 21.18 ? 2625 HOH A O 1 HETATM 9174 O O . HOH G 7 . ? 35.341 55.031 -34.568 1.00 39.28 ? 2626 HOH A O 1 HETATM 9175 O O . HOH G 7 . ? 37.232 52.448 -32.252 1.00 33.29 ? 2627 HOH A O 1 HETATM 9176 O O . HOH G 7 . ? 38.477 54.818 -31.526 1.00 21.15 ? 2628 HOH A O 1 HETATM 9177 O O . HOH G 7 . ? 40.716 55.521 -33.190 1.00 31.33 ? 2629 HOH A O 1 HETATM 9178 O O . HOH G 7 . ? 38.420 51.103 -29.703 1.00 28.48 ? 2630 HOH A O 1 HETATM 9179 O O . HOH G 7 . ? 43.710 54.748 -26.742 1.00 38.46 ? 2631 HOH A O 1 HETATM 9180 O O . HOH G 7 . ? 51.315 53.056 -23.800 1.00 17.43 ? 2632 HOH A O 1 HETATM 9181 O O . HOH G 7 . ? 58.831 53.429 -22.086 1.00 24.35 ? 2633 HOH A O 1 HETATM 9182 O O . HOH G 7 . ? 61.318 54.015 -28.719 1.00 28.44 ? 2634 HOH A O 1 HETATM 9183 O O . HOH G 7 . ? 59.844 52.747 -30.497 1.00 37.06 ? 2635 HOH A O 1 HETATM 9184 O O . HOH G 7 . ? 56.417 49.794 -30.135 1.00 45.62 ? 2636 HOH A O 1 HETATM 9185 O O . HOH G 7 . ? 58.417 43.962 -27.983 1.00 42.06 ? 2637 HOH A O 1 HETATM 9186 O O . HOH G 7 . ? 58.278 37.060 -17.974 1.00 48.30 ? 2638 HOH A O 1 HETATM 9187 O O . HOH G 7 . ? 59.338 37.429 -15.144 1.00 32.53 ? 2639 HOH A O 1 HETATM 9188 O O . HOH G 7 . ? 57.204 35.867 -14.139 1.00 31.83 ? 2640 HOH A O 1 HETATM 9189 O O . HOH G 7 . ? 58.420 34.634 -12.025 1.00 40.72 ? 2641 HOH A O 1 HETATM 9190 O O . HOH G 7 . ? 58.119 34.636 -6.055 1.00 42.48 ? 2642 HOH A O 1 HETATM 9191 O O . HOH G 7 . ? 57.887 42.129 1.755 1.00 26.82 ? 2643 HOH A O 1 HETATM 9192 O O . HOH G 7 . ? 59.378 44.706 5.067 1.00 42.77 ? 2644 HOH A O 1 HETATM 9193 O O . HOH G 7 . ? 58.824 46.141 -1.315 1.00 27.40 ? 2645 HOH A O 1 HETATM 9194 O O . HOH G 7 . ? 61.069 45.090 -3.668 1.00 34.95 ? 2646 HOH A O 1 HETATM 9195 O O . HOH G 7 . ? 70.823 49.157 -0.023 1.00 27.84 ? 2647 HOH A O 1 HETATM 9196 O O . HOH G 7 . ? 72.247 50.198 1.702 1.00 48.29 ? 2648 HOH A O 1 HETATM 9197 O O . HOH G 7 . ? 74.244 51.965 1.637 1.00 39.43 ? 2649 HOH A O 1 HETATM 9198 O O . HOH G 7 . ? 79.571 51.179 -0.402 1.00 30.68 ? 2650 HOH A O 1 HETATM 9199 O O . HOH G 7 . ? 75.743 48.300 -5.474 1.00 44.70 ? 2651 HOH A O 1 HETATM 9200 O O . HOH G 7 . ? 73.653 46.288 -5.331 1.00 47.05 ? 2652 HOH A O 1 HETATM 9201 O O . HOH G 7 . ? 76.435 46.792 -11.466 1.00 32.23 ? 2653 HOH A O 1 HETATM 9202 O O . HOH G 7 . ? 79.375 50.652 -11.220 1.00 52.47 ? 2654 HOH A O 1 HETATM 9203 O O . HOH G 7 . ? 79.300 50.436 -8.875 1.00 35.20 ? 2655 HOH A O 1 HETATM 9204 O O . HOH G 7 . ? 78.353 53.298 -11.945 1.00 34.88 ? 2656 HOH A O 1 HETATM 9205 O O . HOH G 7 . ? 73.912 53.606 -13.658 1.00 46.25 ? 2657 HOH A O 1 HETATM 9206 O O . HOH G 7 . ? 75.204 52.409 -15.534 1.00 39.38 ? 2658 HOH A O 1 HETATM 9207 O O . HOH G 7 . ? 71.047 54.103 -13.839 1.00 32.68 ? 2659 HOH A O 1 HETATM 9208 O O . HOH G 7 . ? 70.327 56.152 -12.333 1.00 34.84 ? 2660 HOH A O 1 HETATM 9209 O O . HOH G 7 . ? 72.090 58.462 -11.120 1.00 30.03 ? 2661 HOH A O 1 HETATM 9210 O O . HOH G 7 . ? 74.164 59.868 -9.439 1.00 36.97 ? 2662 HOH A O 1 HETATM 9211 O O . HOH G 7 . ? 73.050 64.784 -7.711 1.00 25.94 ? 2663 HOH A O 1 HETATM 9212 O O . HOH G 7 . ? 72.842 66.334 -9.986 1.00 29.56 ? 2664 HOH A O 1 HETATM 9213 O O . HOH G 7 . ? 69.928 69.659 -12.566 1.00 18.78 ? 2665 HOH A O 1 HETATM 9214 O O . HOH G 7 . ? 73.885 65.700 -17.453 1.00 21.99 ? 2666 HOH A O 1 HETATM 9215 O O . HOH G 7 . ? 75.217 63.913 -16.264 1.00 33.95 ? 2667 HOH A O 1 HETATM 9216 O O . HOH G 7 . ? 79.650 67.785 -15.193 1.00 36.88 ? 2668 HOH A O 1 HETATM 9217 O O . HOH G 7 . ? 79.855 73.650 -17.516 1.00 35.63 ? 2669 HOH A O 1 HETATM 9218 O O . HOH G 7 . ? 77.505 75.052 -17.539 1.00 37.46 ? 2670 HOH A O 1 HETATM 9219 O O . HOH G 7 . ? 75.405 73.887 -19.400 1.00 28.51 ? 2671 HOH A O 1 HETATM 9220 O O . HOH G 7 . ? 75.266 73.597 -16.070 1.00 35.30 ? 2672 HOH A O 1 HETATM 9221 O O . HOH G 7 . ? 74.759 75.983 -14.481 1.00 32.35 ? 2673 HOH A O 1 HETATM 9222 O O . HOH G 7 . ? 73.732 78.301 -13.290 1.00 45.64 ? 2674 HOH A O 1 HETATM 9223 O O . HOH G 7 . ? 73.679 79.949 -10.703 1.00 47.22 ? 2675 HOH A O 1 HETATM 9224 O O . HOH G 7 . ? 69.904 83.516 -17.418 1.00 51.07 ? 2676 HOH A O 1 HETATM 9225 O O . HOH G 7 . ? 71.590 84.245 -20.060 1.00 33.73 ? 2677 HOH A O 1 HETATM 9226 O O . HOH G 7 . ? 73.227 82.005 -21.198 1.00 31.36 ? 2678 HOH A O 1 HETATM 9227 O O . HOH G 7 . ? 73.946 86.284 -23.278 1.00 47.48 ? 2679 HOH A O 1 HETATM 9228 O O . HOH G 7 . ? 71.314 81.953 -27.636 1.00 38.47 ? 2680 HOH A O 1 HETATM 9229 O O . HOH G 7 . ? 69.967 82.701 -29.776 1.00 26.04 ? 2681 HOH A O 1 HETATM 9230 O O . HOH G 7 . ? 68.435 79.130 -28.562 1.00 27.40 ? 2682 HOH A O 1 HETATM 9231 O O . HOH G 7 . ? 76.522 73.599 -26.772 1.00 41.91 ? 2683 HOH A O 1 HETATM 9232 O O . HOH G 7 . ? 74.706 77.052 -20.695 1.00 39.43 ? 2684 HOH A O 1 HETATM 9233 O O . HOH G 7 . ? 73.304 76.516 -18.492 1.00 35.11 ? 2685 HOH A O 1 HETATM 9234 O O . HOH G 7 . ? 68.482 78.498 -18.146 1.00 28.53 ? 2686 HOH A O 1 HETATM 9235 O O . HOH G 7 . ? 60.103 83.600 -16.701 1.00 42.88 ? 2687 HOH A O 1 HETATM 9236 O O . HOH G 7 . ? 56.826 87.396 -20.131 1.00 33.61 ? 2688 HOH A O 1 HETATM 9237 O O . HOH G 7 . ? 53.118 86.487 -21.431 1.00 32.53 ? 2689 HOH A O 1 HETATM 9238 O O . HOH G 7 . ? 54.882 80.728 -23.603 1.00 17.08 ? 2690 HOH A O 1 HETATM 9239 O O . HOH G 7 . ? 49.907 73.299 -21.762 1.00 33.76 ? 2691 HOH A O 1 HETATM 9240 O O . HOH G 7 . ? 44.959 71.544 -25.660 1.00 47.19 ? 2692 HOH A O 1 HETATM 9241 O O . HOH G 7 . ? 43.433 68.020 -25.211 1.00 19.36 ? 2693 HOH A O 1 HETATM 9242 O O . HOH G 7 . ? 45.900 67.777 -26.907 1.00 20.55 ? 2694 HOH A O 1 HETATM 9243 O O . HOH G 7 . ? 47.114 67.476 -24.591 1.00 28.53 ? 2695 HOH A O 1 HETATM 9244 O O . HOH G 7 . ? 47.889 64.691 -27.585 1.00 39.23 ? 2696 HOH A O 1 HETATM 9245 O O . HOH G 7 . ? 47.392 67.896 -30.776 1.00 22.51 ? 2697 HOH A O 1 HETATM 9246 O O . HOH G 7 . ? 47.306 69.739 -28.520 1.00 27.35 ? 2698 HOH A O 1 HETATM 9247 O O . HOH G 7 . ? 43.396 66.448 -32.275 1.00 32.82 ? 2699 HOH A O 1 HETATM 9248 O O . HOH G 7 . ? 41.288 67.978 -32.357 1.00 23.87 ? 2700 HOH A O 1 HETATM 9249 O O . HOH G 7 . ? 39.328 68.721 -35.300 1.00 22.46 ? 2701 HOH A O 1 HETATM 9250 O O . HOH G 7 . ? 38.551 68.753 -38.065 1.00 22.53 ? 2702 HOH A O 1 HETATM 9251 O O . HOH G 7 . ? 34.633 65.513 -42.206 1.00 38.46 ? 2703 HOH A O 1 HETATM 9252 O O . HOH G 7 . ? 34.434 69.808 -44.802 1.00 46.36 ? 2704 HOH A O 1 HETATM 9253 O O . HOH G 7 . ? 30.899 68.992 -45.489 1.00 42.74 ? 2705 HOH A O 1 HETATM 9254 O O . HOH G 7 . ? 27.939 67.600 -46.861 1.00 41.72 ? 2706 HOH A O 1 HETATM 9255 O O . HOH G 7 . ? 23.797 64.970 -43.647 1.00 45.34 ? 2707 HOH A O 1 HETATM 9256 O O . HOH G 7 . ? 28.942 61.901 -39.701 1.00 28.53 ? 2708 HOH A O 1 HETATM 9257 O O . HOH G 7 . ? 28.442 59.443 -38.978 1.00 37.51 ? 2709 HOH A O 1 HETATM 9258 O O . HOH G 7 . ? 31.089 57.975 -40.290 1.00 47.09 ? 2710 HOH A O 1 HETATM 9259 O O . HOH G 7 . ? 36.260 62.268 -38.391 1.00 33.95 ? 2711 HOH A O 1 HETATM 9260 O O . HOH G 7 . ? 35.924 62.998 -33.601 1.00 39.10 ? 2712 HOH A O 1 HETATM 9261 O O . HOH G 7 . ? 34.039 64.106 -32.181 1.00 18.54 ? 2713 HOH A O 1 HETATM 9262 O O . HOH G 7 . ? 32.040 58.241 -28.379 1.00 18.24 ? 2714 HOH A O 1 HETATM 9263 O O . HOH G 7 . ? 34.042 55.994 -26.180 1.00 15.54 ? 2715 HOH A O 1 HETATM 9264 O O . HOH G 7 . ? 31.831 50.930 -35.323 1.00 29.46 ? 2716 HOH A O 1 HETATM 9265 O O . HOH G 7 . ? 28.877 69.305 -39.562 1.00 28.69 ? 2717 HOH A O 1 HETATM 9266 O O . HOH G 7 . ? 24.707 71.180 -39.913 1.00 34.56 ? 2718 HOH A O 1 HETATM 9267 O O . HOH G 7 . ? 31.126 78.384 -42.961 1.00 35.68 ? 2719 HOH A O 1 HETATM 9268 O O . HOH G 7 . ? 30.202 81.250 -42.896 1.00 48.09 ? 2720 HOH A O 1 HETATM 9269 O O . HOH G 7 . ? 28.973 81.413 -35.616 1.00 23.23 ? 2721 HOH A O 1 HETATM 9270 O O . HOH G 7 . ? 28.029 84.107 -35.470 1.00 21.33 ? 2722 HOH A O 1 HETATM 9271 O O . HOH G 7 . ? 23.269 88.306 -38.329 1.00 40.05 ? 2723 HOH A O 1 HETATM 9272 O O . HOH G 7 . ? 28.922 93.287 -38.693 1.00 29.78 ? 2724 HOH A O 1 HETATM 9273 O O . HOH G 7 . ? 32.040 92.102 -36.833 1.00 30.67 ? 2725 HOH A O 1 HETATM 9274 O O . HOH G 7 . ? 34.998 94.556 -32.304 1.00 34.14 ? 2726 HOH A O 1 HETATM 9275 O O . HOH G 7 . ? 36.041 93.263 -30.039 1.00 37.72 ? 2727 HOH A O 1 HETATM 9276 O O . HOH G 7 . ? 31.799 96.611 -27.400 1.00 40.31 ? 2728 HOH A O 1 HETATM 9277 O O . HOH G 7 . ? 27.857 101.748 -19.250 1.00 34.75 ? 2729 HOH A O 1 HETATM 9278 O O . HOH G 7 . ? 27.188 88.158 -12.564 1.00 34.13 ? 2730 HOH A O 1 HETATM 9279 O O . HOH G 7 . ? 32.088 84.867 -8.438 1.00 25.33 ? 2731 HOH A O 1 HETATM 9280 O O . HOH G 7 . ? 33.562 83.257 -10.356 1.00 19.12 ? 2732 HOH A O 1 HETATM 9281 O O . HOH G 7 . ? 32.734 80.754 -11.667 1.00 15.04 ? 2733 HOH A O 1 HETATM 9282 O O . HOH G 7 . ? 34.530 78.833 -9.120 1.00 15.19 ? 2734 HOH A O 1 HETATM 9283 O O . HOH G 7 . ? 35.816 77.290 -7.278 1.00 17.78 ? 2735 HOH A O 1 HETATM 9284 O O . HOH G 7 . ? 36.286 78.992 -4.996 1.00 23.42 ? 2736 HOH A O 1 HETATM 9285 O O . HOH G 7 . ? 33.380 78.385 -5.073 1.00 17.50 ? 2737 HOH A O 1 HETATM 9286 O O . HOH G 7 . ? 31.399 76.452 -6.252 1.00 16.00 ? 2738 HOH A O 1 HETATM 9287 O O . HOH G 7 . ? 37.045 71.595 -4.541 1.00 13.27 ? 2739 HOH A O 1 HETATM 9288 O O . HOH G 7 . ? 37.902 73.106 -2.275 1.00 14.84 ? 2740 HOH A O 1 HETATM 9289 O O . HOH G 7 . ? 36.583 72.433 0.246 1.00 13.32 ? 2741 HOH A O 1 HETATM 9290 O O . HOH G 7 . ? 37.619 80.254 -0.647 1.00 26.52 ? 2742 HOH A O 1 HETATM 9291 O O . HOH G 7 . ? 38.740 80.040 -3.015 1.00 33.16 ? 2743 HOH A O 1 HETATM 9292 O O . HOH G 7 . ? 38.020 82.864 -0.861 1.00 31.11 ? 2744 HOH A O 1 HETATM 9293 O O . HOH G 7 . ? 37.329 83.291 -4.083 1.00 30.69 ? 2745 HOH A O 1 HETATM 9294 O O . HOH G 7 . ? 34.964 85.114 -0.915 1.00 47.72 ? 2746 HOH A O 1 HETATM 9295 O O . HOH G 7 . ? 32.783 84.000 0.296 1.00 34.50 ? 2747 HOH A O 1 HETATM 9296 O O . HOH G 7 . ? 31.320 81.469 0.530 1.00 22.32 ? 2748 HOH A O 1 HETATM 9297 O O . HOH G 7 . ? 24.794 83.561 2.644 1.00 35.14 ? 2749 HOH A O 1 HETATM 9298 O O . HOH G 7 . ? 21.162 86.608 -2.556 1.00 44.23 ? 2750 HOH A O 1 HETATM 9299 O O . HOH G 7 . ? 18.664 84.593 -4.889 1.00 46.57 ? 2751 HOH A O 1 HETATM 9300 O O . HOH G 7 . ? 18.198 84.415 -7.979 1.00 44.96 ? 2752 HOH A O 1 HETATM 9301 O O . HOH G 7 . ? 17.249 80.433 -7.381 1.00 29.31 ? 2753 HOH A O 1 HETATM 9302 O O . HOH G 7 . ? 18.815 80.347 -11.762 1.00 40.53 ? 2754 HOH A O 1 HETATM 9303 O O . HOH G 7 . ? 20.907 83.537 -12.497 1.00 36.50 ? 2755 HOH A O 1 HETATM 9304 O O . HOH G 7 . ? 17.422 81.118 -17.155 1.00 41.87 ? 2756 HOH A O 1 HETATM 9305 O O . HOH G 7 . ? 15.272 76.634 -13.599 1.00 35.98 ? 2757 HOH A O 1 HETATM 9306 O O . HOH G 7 . ? 15.854 74.923 -11.470 1.00 26.64 ? 2758 HOH A O 1 HETATM 9307 O O . HOH G 7 . ? 12.251 74.903 -13.264 1.00 33.29 ? 2759 HOH A O 1 HETATM 9308 O O . HOH G 7 . ? 12.958 74.408 -18.948 1.00 40.02 ? 2760 HOH A O 1 HETATM 9309 O O . HOH G 7 . ? 13.903 87.907 -19.876 1.00 40.81 ? 2761 HOH A O 1 HETATM 9310 O O . HOH G 7 . ? 7.871 80.895 -4.240 1.00 38.53 ? 2762 HOH A O 1 HETATM 9311 O O . HOH G 7 . ? 5.374 80.762 -3.417 1.00 38.17 ? 2763 HOH A O 1 HETATM 9312 O O . HOH G 7 . ? 10.552 76.737 -4.681 1.00 38.00 ? 2764 HOH A O 1 HETATM 9313 O O . HOH G 7 . ? 12.640 70.714 -0.259 1.00 27.81 ? 2765 HOH A O 1 HETATM 9314 O O . HOH G 7 . ? 13.294 68.415 1.117 1.00 25.83 ? 2766 HOH A O 1 HETATM 9315 O O . HOH G 7 . ? 10.635 67.879 -2.053 1.00 36.12 ? 2767 HOH A O 1 HETATM 9316 O O . HOH G 7 . ? 7.897 58.098 0.099 1.00 40.28 ? 2768 HOH A O 1 HETATM 9317 O O . HOH G 7 . ? 8.636 57.340 -6.747 1.00 30.34 ? 2769 HOH A O 1 HETATM 9318 O O . HOH G 7 . ? 8.704 54.595 -6.072 1.00 31.05 ? 2770 HOH A O 1 HETATM 9319 O O . HOH G 7 . ? 7.915 52.529 -7.369 1.00 47.99 ? 2771 HOH A O 1 HETATM 9320 O O . HOH G 7 . ? 7.535 53.837 -10.012 1.00 32.16 ? 2772 HOH A O 1 HETATM 9321 O O . HOH G 7 . ? 5.040 52.584 -6.101 1.00 36.05 ? 2773 HOH A O 1 HETATM 9322 O O . HOH G 7 . ? 4.283 56.230 -6.358 1.00 35.88 ? 2774 HOH A O 1 HETATM 9323 O O . HOH G 7 . ? 11.744 54.813 -12.224 1.00 21.59 ? 2775 HOH A O 1 HETATM 9324 O O . HOH G 7 . ? 12.281 55.532 -15.069 1.00 22.05 ? 2776 HOH A O 1 HETATM 9325 O O . HOH G 7 . ? 14.317 54.074 -16.089 1.00 23.96 ? 2777 HOH A O 1 HETATM 9326 O O . HOH G 7 . ? 13.211 51.828 -15.107 1.00 33.66 ? 2778 HOH A O 1 HETATM 9327 O O . HOH G 7 . ? 12.750 51.452 -12.067 1.00 34.53 ? 2779 HOH A O 1 HETATM 9328 O O . HOH G 7 . ? 9.465 47.588 -8.407 1.00 43.48 ? 2780 HOH A O 1 HETATM 9329 O O . HOH G 7 . ? 11.685 47.886 -2.262 1.00 35.21 ? 2781 HOH A O 1 HETATM 9330 O O . HOH G 7 . ? 13.363 50.553 -1.479 1.00 26.49 ? 2782 HOH A O 1 HETATM 9331 O O . HOH G 7 . ? 14.293 50.482 1.150 1.00 29.80 ? 2783 HOH A O 1 HETATM 9332 O O . HOH G 7 . ? 13.345 48.220 1.773 1.00 35.33 ? 2784 HOH A O 1 HETATM 9333 O O . HOH G 7 . ? 10.437 51.353 2.577 1.00 32.39 ? 2785 HOH A O 1 HETATM 9334 O O . HOH G 7 . ? 10.934 53.448 4.260 1.00 35.71 ? 2786 HOH A O 1 HETATM 9335 O O . HOH G 7 . ? 11.339 52.959 6.956 1.00 22.16 ? 2787 HOH A O 1 HETATM 9336 O O . HOH G 7 . ? 13.783 53.921 4.551 1.00 19.48 ? 2788 HOH A O 1 HETATM 9337 O O . HOH G 7 . ? 13.467 53.199 1.949 1.00 22.03 ? 2789 HOH A O 1 HETATM 9338 O O . HOH G 7 . ? 12.386 56.102 5.441 1.00 20.51 ? 2790 HOH A O 1 HETATM 9339 O O . HOH G 7 . ? 5.497 57.585 7.204 1.00 37.45 ? 2791 HOH A O 1 HETATM 9340 O O . HOH G 7 . ? 8.998 50.114 8.227 1.00 34.33 ? 2792 HOH A O 1 HETATM 9341 O O . HOH G 7 . ? 6.416 46.259 16.621 1.00 39.85 ? 2793 HOH A O 1 HETATM 9342 O O . HOH G 7 . ? 12.125 41.208 20.065 1.00 33.45 ? 2794 HOH A O 1 HETATM 9343 O O . HOH G 7 . ? 18.058 41.680 25.462 1.00 31.71 ? 2795 HOH A O 1 HETATM 9344 O O . HOH G 7 . ? 18.141 43.003 27.561 1.00 37.64 ? 2796 HOH A O 1 HETATM 9345 O O . HOH G 7 . ? 19.060 39.657 26.662 1.00 34.19 ? 2797 HOH A O 1 HETATM 9346 O O . HOH G 7 . ? 19.803 35.505 25.739 1.00 35.79 ? 2798 HOH A O 1 HETATM 9347 O O . HOH G 7 . ? 22.699 31.187 29.755 1.00 36.32 ? 2799 HOH A O 1 HETATM 9348 O O . HOH G 7 . ? 20.764 31.495 31.554 1.00 42.45 ? 2800 HOH A O 1 HETATM 9349 O O . HOH G 7 . ? 21.882 29.018 28.343 1.00 41.57 ? 2801 HOH A O 1 HETATM 9350 O O . HOH G 7 . ? 26.131 32.668 29.011 1.00 30.41 ? 2802 HOH A O 1 HETATM 9351 O O . HOH G 7 . ? 27.286 34.883 29.626 1.00 28.73 ? 2803 HOH A O 1 HETATM 9352 O O . HOH G 7 . ? 26.313 37.258 29.588 1.00 23.47 ? 2804 HOH A O 1 HETATM 9353 O O . HOH G 7 . ? 30.192 36.504 29.125 1.00 27.22 ? 2805 HOH A O 1 HETATM 9354 O O . HOH G 7 . ? 28.440 34.937 32.230 1.00 42.93 ? 2806 HOH A O 1 HETATM 9355 O O . HOH G 7 . ? 24.736 34.352 35.910 1.00 41.79 ? 2807 HOH A O 1 HETATM 9356 O O . HOH G 7 . ? 22.292 34.987 34.953 1.00 40.28 ? 2808 HOH A O 1 HETATM 9357 O O . HOH G 7 . ? 17.881 39.498 35.772 1.00 44.36 ? 2809 HOH A O 1 HETATM 9358 O O . HOH G 7 . ? 21.180 41.600 35.376 1.00 36.24 ? 2810 HOH A O 1 HETATM 9359 O O . HOH G 7 . ? 19.859 43.161 34.036 1.00 29.94 ? 2811 HOH A O 1 HETATM 9360 O O . HOH G 7 . ? 17.214 41.664 32.394 1.00 42.37 ? 2812 HOH A O 1 HETATM 9361 O O . HOH G 7 . ? 14.577 47.016 32.485 1.00 35.94 ? 2813 HOH A O 1 HETATM 9362 O O . HOH G 7 . ? 12.355 47.484 31.347 1.00 38.56 ? 2814 HOH A O 1 HETATM 9363 O O . HOH G 7 . ? 16.521 48.882 24.195 1.00 19.88 ? 2815 HOH A O 1 HETATM 9364 O O . HOH G 7 . ? 14.612 55.568 27.453 1.00 29.97 ? 2816 HOH A O 1 HETATM 9365 O O . HOH G 7 . ? 18.437 58.968 31.701 1.00 39.72 ? 2817 HOH A O 1 HETATM 9366 O O . HOH G 7 . ? 23.082 55.906 30.826 1.00 21.67 ? 2818 HOH A O 1 HETATM 9367 O O . HOH G 7 . ? 18.115 60.451 24.474 1.00 21.98 ? 2819 HOH A O 1 HETATM 9368 O O . HOH G 7 . ? 17.864 65.955 27.799 1.00 33.56 ? 2820 HOH A O 1 HETATM 9369 O O . HOH G 7 . ? 16.962 66.086 29.906 1.00 46.15 ? 2821 HOH A O 1 HETATM 9370 O O . HOH G 7 . ? 14.081 63.084 30.176 1.00 49.01 ? 2822 HOH A O 1 HETATM 9371 O O . HOH G 7 . ? 14.061 69.241 26.957 1.00 29.68 ? 2823 HOH A O 1 HETATM 9372 O O . HOH G 7 . ? 15.047 69.669 24.383 1.00 45.09 ? 2824 HOH A O 1 HETATM 9373 O O . HOH G 7 . ? 11.028 69.306 26.263 1.00 36.79 ? 2825 HOH A O 1 HETATM 9374 O O . HOH G 7 . ? 13.768 62.112 14.767 1.00 31.79 ? 2826 HOH A O 1 HETATM 9375 O O . HOH G 7 . ? 13.161 62.477 11.999 1.00 35.77 ? 2827 HOH A O 1 HETATM 9376 O O . HOH G 7 . ? 27.661 53.203 20.159 1.00 18.59 ? 2828 HOH A O 1 HETATM 9377 O O . HOH G 7 . ? 27.001 52.099 22.649 1.00 28.76 ? 2829 HOH A O 1 HETATM 9378 O O . HOH G 7 . ? 27.392 50.036 23.325 1.00 31.52 ? 2830 HOH A O 1 HETATM 9379 O O . HOH G 7 . ? 30.155 55.590 17.280 1.00 14.12 ? 2831 HOH A O 1 HETATM 9380 O O . HOH G 7 . ? 33.688 60.134 23.294 1.00 16.46 ? 2832 HOH A O 1 HETATM 9381 O O . HOH G 7 . ? 28.863 64.258 30.150 1.00 24.86 ? 2833 HOH A O 1 HETATM 9382 O O . HOH G 7 . ? 27.783 67.391 28.198 1.00 22.28 ? 2834 HOH A O 1 HETATM 9383 O O . HOH G 7 . ? 27.173 71.949 34.019 1.00 39.38 ? 2835 HOH A O 1 HETATM 9384 O O . HOH G 7 . ? 29.627 72.181 34.207 1.00 27.72 ? 2836 HOH A O 1 HETATM 9385 O O . HOH G 7 . ? 29.622 73.400 36.617 1.00 43.37 ? 2837 HOH A O 1 HETATM 9386 O O . HOH G 7 . ? 26.244 69.267 35.382 1.00 43.45 ? 2838 HOH A O 1 HETATM 9387 O O . HOH G 7 . ? 27.713 52.004 42.519 1.00 37.89 ? 2839 HOH A O 1 HETATM 9388 O O . HOH G 7 . ? 27.889 47.315 46.059 1.00 47.80 ? 2840 HOH A O 1 HETATM 9389 O O . HOH G 7 . ? 21.095 51.653 47.596 1.00 33.39 ? 2841 HOH A O 1 HETATM 9390 O O . HOH G 7 . ? 21.182 53.984 46.865 1.00 43.66 ? 2842 HOH A O 1 HETATM 9391 O O . HOH G 7 . ? 29.328 31.430 21.974 1.00 41.04 ? 2843 HOH A O 1 HETATM 9392 O O . HOH G 7 . ? 31.709 33.477 17.208 1.00 34.13 ? 2844 HOH A O 1 HETATM 9393 O O . HOH G 7 . ? 34.247 34.234 16.333 1.00 26.69 ? 2845 HOH A O 1 HETATM 9394 O O . HOH G 7 . ? 36.808 29.022 13.206 1.00 33.45 ? 2846 HOH A O 1 HETATM 9395 O O . HOH G 7 . ? 24.990 39.883 14.326 1.00 22.67 ? 2847 HOH A O 1 HETATM 9396 O O . HOH G 7 . ? 18.170 36.634 5.847 1.00 39.25 ? 2848 HOH A O 1 HETATM 9397 O O . HOH G 7 . ? 21.233 35.382 -5.069 1.00 37.76 ? 2849 HOH A O 1 HETATM 9398 O O . HOH G 7 . ? 15.865 44.722 -11.466 1.00 46.46 ? 2850 HOH A O 1 HETATM 9399 O O . HOH G 7 . ? 26.225 48.646 -10.853 1.00 14.66 ? 2851 HOH A O 1 HETATM 9400 O O . HOH G 7 . ? 26.058 49.358 -13.600 1.00 15.12 ? 2852 HOH A O 1 HETATM 9401 O O . HOH G 7 . ? 23.823 38.741 -20.858 1.00 40.15 ? 2853 HOH A O 1 HETATM 9402 O O . HOH G 7 . ? 44.608 33.136 -19.148 1.00 49.24 ? 2854 HOH A O 1 HETATM 9403 O O . HOH G 7 . ? 60.342 60.684 -18.044 1.00 15.39 ? 2855 HOH A O 1 HETATM 9404 O O . HOH G 7 . ? 53.623 64.554 -19.782 1.00 12.81 ? 2856 HOH A O 1 HETATM 9405 O O . HOH G 7 . ? 61.712 63.474 -30.562 1.00 33.12 ? 2857 HOH A O 1 HETATM 9406 O O . HOH G 7 . ? 63.545 67.580 -31.482 1.00 35.82 ? 2858 HOH A O 1 HETATM 9407 O O . HOH G 7 . ? 69.659 63.580 -28.521 1.00 30.30 ? 2859 HOH A O 1 HETATM 9408 O O . HOH G 7 . ? 66.804 59.693 -27.056 1.00 24.10 ? 2860 HOH A O 1 HETATM 9409 O O . HOH G 7 . ? 66.479 58.017 -30.902 1.00 44.28 ? 2861 HOH A O 1 HETATM 9410 O O . HOH G 7 . ? 69.975 58.763 -17.189 1.00 39.38 ? 2862 HOH A O 1 HETATM 9411 O O . HOH G 7 . ? 68.821 56.920 -16.604 1.00 39.38 ? 2863 HOH A O 1 HETATM 9412 O O . HOH G 7 . ? 70.581 51.842 -12.507 1.00 23.56 ? 2864 HOH A O 1 HETATM 9413 O O . HOH G 7 . ? 69.972 53.411 -10.154 1.00 36.55 ? 2865 HOH A O 1 HETATM 9414 O O . HOH G 7 . ? 66.499 62.311 -13.026 1.00 21.64 ? 2866 HOH A O 1 HETATM 9415 O O . HOH G 7 . ? 67.018 55.042 0.914 1.00 24.40 ? 2867 HOH A O 1 HETATM 9416 O O . HOH G 7 . ? 65.719 77.336 2.876 1.00 37.90 ? 2868 HOH A O 1 HETATM 9417 O O . HOH G 7 . ? 51.627 79.863 0.822 1.00 41.60 ? 2869 HOH A O 1 HETATM 9418 O O . HOH G 7 . ? 51.236 79.123 -1.812 1.00 28.92 ? 2870 HOH A O 1 HETATM 9419 O O . HOH G 7 . ? 48.019 80.095 -4.392 1.00 45.10 ? 2871 HOH A O 1 HETATM 9420 O O . HOH G 7 . ? 45.209 80.273 -1.528 1.00 35.65 ? 2872 HOH A O 1 HETATM 9421 O O . HOH G 7 . ? 46.468 82.396 -0.865 1.00 44.24 ? 2873 HOH A O 1 HETATM 9422 O O . HOH G 7 . ? 46.125 79.352 4.911 1.00 31.96 ? 2874 HOH A O 1 HETATM 9423 O O . HOH G 7 . ? 43.413 80.360 5.214 1.00 27.90 ? 2875 HOH A O 1 HETATM 9424 O O . HOH G 7 . ? 46.699 74.211 7.739 1.00 15.07 ? 2876 HOH A O 1 HETATM 9425 O O . HOH G 7 . ? 43.480 72.892 5.776 1.00 15.46 ? 2877 HOH A O 1 HETATM 9426 O O . HOH G 7 . ? 46.079 70.721 0.049 1.00 18.82 ? 2878 HOH A O 1 HETATM 9427 O O . HOH G 7 . ? 42.012 63.208 -7.121 1.00 10.55 ? 2879 HOH A O 1 HETATM 9428 O O . HOH G 7 . ? 42.107 74.946 -15.973 1.00 18.97 ? 2880 HOH A O 1 HETATM 9429 O O . HOH G 7 . ? 41.266 77.264 -14.089 1.00 17.98 ? 2881 HOH A O 1 HETATM 9430 O O . HOH G 7 . ? 35.466 85.868 -8.076 1.00 39.10 ? 2882 HOH A O 1 HETATM 9431 O O . HOH G 7 . ? 34.201 86.830 -10.319 1.00 34.29 ? 2883 HOH A O 1 HETATM 9432 O O . HOH G 7 . ? 32.801 85.069 -5.611 1.00 22.18 ? 2884 HOH A O 1 HETATM 9433 O O . HOH G 7 . ? 26.677 87.620 -3.809 1.00 39.82 ? 2885 HOH A O 1 HETATM 9434 O O . HOH G 7 . ? 51.789 81.717 -5.345 1.00 48.08 ? 2886 HOH A O 1 HETATM 9435 O O . HOH G 7 . ? 60.269 91.492 -28.577 1.00 37.50 ? 2887 HOH A O 1 HETATM 9436 O O . HOH G 7 . ? 72.268 95.183 -31.270 1.00 32.53 ? 2888 HOH A O 1 HETATM 9437 O O . HOH G 7 . ? 70.814 95.036 -35.074 1.00 38.31 ? 2889 HOH A O 1 HETATM 9438 O O . HOH G 7 . ? 58.292 76.851 -38.488 1.00 19.27 ? 2890 HOH A O 1 HETATM 9439 O O . HOH G 7 . ? 51.286 75.748 -40.854 1.00 35.27 ? 2891 HOH A O 1 HETATM 9440 O O . HOH G 7 . ? 47.476 78.554 -40.327 1.00 23.49 ? 2892 HOH A O 1 HETATM 9441 O O . HOH G 7 . ? 46.471 79.882 -42.552 1.00 26.54 ? 2893 HOH A O 1 HETATM 9442 O O . HOH G 7 . ? 43.808 79.553 -42.520 1.00 31.76 ? 2894 HOH A O 1 HETATM 9443 O O . HOH G 7 . ? 45.368 83.372 -42.965 1.00 39.05 ? 2895 HOH A O 1 HETATM 9444 O O . HOH G 7 . ? 49.744 81.877 -43.834 1.00 22.12 ? 2896 HOH A O 1 HETATM 9445 O O . HOH G 7 . ? 54.241 82.397 -44.305 1.00 49.48 ? 2897 HOH A O 1 HETATM 9446 O O . HOH G 7 . ? 48.596 95.603 -44.276 1.00 48.44 ? 2898 HOH A O 1 HETATM 9447 O O . HOH G 7 . ? 46.084 96.525 -43.872 1.00 31.61 ? 2899 HOH A O 1 HETATM 9448 O O . HOH G 7 . ? 32.364 77.299 -29.597 1.00 18.53 ? 2900 HOH A O 1 HETATM 9449 O O . HOH G 7 . ? 30.244 74.507 -29.182 1.00 16.79 ? 2901 HOH A O 1 HETATM 9450 O O . HOH G 7 . ? 44.971 66.049 -34.569 1.00 42.48 ? 2902 HOH A O 1 HETATM 9451 O O . HOH G 7 . ? 61.514 68.728 -41.693 1.00 35.49 ? 2903 HOH A O 1 HETATM 9452 O O . HOH G 7 . ? 31.274 68.078 14.401 1.00 35.27 ? 2904 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 1045 SER SER A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1802 1 NAG NAG A . C 3 PO4 1 1803 1 PO4 PO4 A . D 4 ZN 1 1805 1 ZN ZN A . E 5 GB2 1 1804 1 GB2 GB2 A . F 6 MPD 1 1801 1 MPD MPD A . G 7 HOH 1 1806 1 HOH WAT A . G 7 HOH 2 1807 2 HOH WAT A . G 7 HOH 3 1808 3 HOH WAT A . G 7 HOH 4 1809 4 HOH WAT A . G 7 HOH 5 1810 5 HOH WAT A . G 7 HOH 6 1811 6 HOH WAT A . G 7 HOH 7 1812 7 HOH WAT A . G 7 HOH 8 1813 8 HOH WAT A . G 7 HOH 9 1814 9 HOH WAT A . G 7 HOH 10 1815 10 HOH WAT A . G 7 HOH 11 1816 11 HOH WAT A . G 7 HOH 12 1817 12 HOH WAT A . G 7 HOH 13 1818 13 HOH WAT A . G 7 HOH 14 1819 14 HOH WAT A . G 7 HOH 15 1820 15 HOH WAT A . G 7 HOH 16 1821 16 HOH WAT A . G 7 HOH 17 1822 17 HOH WAT A . G 7 HOH 18 1823 18 HOH WAT A . G 7 HOH 19 1824 19 HOH WAT A . G 7 HOH 20 1825 20 HOH WAT A . G 7 HOH 21 1826 21 HOH WAT A . G 7 HOH 22 1827 22 HOH WAT A . G 7 HOH 23 1828 23 HOH WAT A . G 7 HOH 24 1829 24 HOH WAT A . G 7 HOH 25 1830 25 HOH WAT A . G 7 HOH 26 1831 26 HOH WAT A . G 7 HOH 27 1832 27 HOH WAT A . G 7 HOH 28 1833 28 HOH WAT A . G 7 HOH 29 1834 29 HOH WAT A . G 7 HOH 30 1835 30 HOH WAT A . G 7 HOH 31 1836 31 HOH WAT A . G 7 HOH 32 1837 32 HOH WAT A . G 7 HOH 33 1838 33 HOH WAT A . G 7 HOH 34 1839 34 HOH WAT A . G 7 HOH 35 1840 35 HOH WAT A . G 7 HOH 36 1841 36 HOH WAT A . G 7 HOH 37 1842 37 HOH WAT A . G 7 HOH 38 1843 38 HOH WAT A . G 7 HOH 39 1844 39 HOH WAT A . G 7 HOH 40 1845 40 HOH WAT A . G 7 HOH 41 1846 41 HOH WAT A . G 7 HOH 42 1847 42 HOH WAT A . G 7 HOH 43 1848 43 HOH WAT A . G 7 HOH 44 1849 44 HOH WAT A . G 7 HOH 45 1850 45 HOH WAT A . G 7 HOH 46 1851 46 HOH WAT A . G 7 HOH 47 1852 47 HOH WAT A . G 7 HOH 48 1853 48 HOH WAT A . G 7 HOH 49 1854 49 HOH WAT A . G 7 HOH 50 1855 50 HOH WAT A . G 7 HOH 51 1856 51 HOH WAT A . G 7 HOH 52 1857 52 HOH WAT A . G 7 HOH 53 1858 53 HOH WAT A . G 7 HOH 54 1859 54 HOH WAT A . G 7 HOH 55 1860 55 HOH WAT A . G 7 HOH 56 1861 56 HOH WAT A . G 7 HOH 57 1862 57 HOH WAT A . G 7 HOH 58 1863 58 HOH WAT A . G 7 HOH 59 1864 59 HOH WAT A . G 7 HOH 60 1865 60 HOH WAT A . G 7 HOH 61 1866 61 HOH WAT A . G 7 HOH 62 1867 62 HOH WAT A . G 7 HOH 63 1868 63 HOH WAT A . G 7 HOH 64 1869 64 HOH WAT A . G 7 HOH 65 1870 65 HOH WAT A . G 7 HOH 66 1871 66 HOH WAT A . G 7 HOH 67 1872 67 HOH WAT A . G 7 HOH 68 1873 68 HOH WAT A . G 7 HOH 69 1874 69 HOH WAT A . G 7 HOH 70 1875 70 HOH WAT A . G 7 HOH 71 1876 71 HOH WAT A . G 7 HOH 72 1877 72 HOH WAT A . G 7 HOH 73 1878 73 HOH WAT A . G 7 HOH 74 1879 74 HOH WAT A . G 7 HOH 75 1880 75 HOH WAT A . G 7 HOH 76 1881 76 HOH WAT A . G 7 HOH 77 1882 77 HOH WAT A . G 7 HOH 78 1883 78 HOH WAT A . G 7 HOH 79 1884 79 HOH WAT A . G 7 HOH 80 1885 80 HOH WAT A . G 7 HOH 81 1886 81 HOH WAT A . G 7 HOH 82 1887 82 HOH WAT A . G 7 HOH 83 1888 83 HOH WAT A . G 7 HOH 84 1889 84 HOH WAT A . G 7 HOH 85 1890 85 HOH WAT A . G 7 HOH 86 1891 86 HOH WAT A . G 7 HOH 87 1892 87 HOH WAT A . G 7 HOH 88 1893 88 HOH WAT A . G 7 HOH 89 1894 89 HOH WAT A . G 7 HOH 90 1895 90 HOH WAT A . G 7 HOH 91 1896 91 HOH WAT A . G 7 HOH 92 1897 92 HOH WAT A . G 7 HOH 93 1898 93 HOH WAT A . G 7 HOH 94 1899 94 HOH WAT A . G 7 HOH 95 1900 95 HOH WAT A . G 7 HOH 96 1901 96 HOH WAT A . G 7 HOH 97 1902 97 HOH WAT A . G 7 HOH 98 1903 98 HOH WAT A . G 7 HOH 99 1904 99 HOH WAT A . G 7 HOH 100 1905 100 HOH WAT A . G 7 HOH 101 1906 101 HOH WAT A . G 7 HOH 102 1907 102 HOH WAT A . G 7 HOH 103 1908 103 HOH WAT A . G 7 HOH 104 1909 104 HOH WAT A . G 7 HOH 105 1910 105 HOH WAT A . G 7 HOH 106 1911 106 HOH WAT A . G 7 HOH 107 1912 107 HOH WAT A . G 7 HOH 108 1913 108 HOH WAT A . G 7 HOH 109 1914 109 HOH WAT A . G 7 HOH 110 1915 110 HOH WAT A . G 7 HOH 111 1916 111 HOH WAT A . G 7 HOH 112 1917 112 HOH WAT A . G 7 HOH 113 1918 113 HOH WAT A . G 7 HOH 114 1919 114 HOH WAT A . G 7 HOH 115 1920 115 HOH WAT A . G 7 HOH 116 1921 116 HOH WAT A . G 7 HOH 117 1922 117 HOH WAT A . G 7 HOH 118 1923 118 HOH WAT A . G 7 HOH 119 1924 119 HOH WAT A . G 7 HOH 120 1925 120 HOH WAT A . G 7 HOH 121 1926 121 HOH WAT A . G 7 HOH 122 1927 122 HOH WAT A . G 7 HOH 123 1928 123 HOH WAT A . G 7 HOH 124 1929 124 HOH WAT A . G 7 HOH 125 1930 125 HOH WAT A . G 7 HOH 126 1931 126 HOH WAT A . G 7 HOH 127 1932 127 HOH WAT A . G 7 HOH 128 1933 128 HOH WAT A . G 7 HOH 129 1934 129 HOH WAT A . G 7 HOH 130 1935 130 HOH WAT A . G 7 HOH 131 1936 131 HOH WAT A . G 7 HOH 132 1937 132 HOH WAT A . G 7 HOH 133 1938 133 HOH WAT A . G 7 HOH 134 1939 134 HOH WAT A . G 7 HOH 135 1940 135 HOH WAT A . G 7 HOH 136 1941 136 HOH WAT A . G 7 HOH 137 1942 137 HOH WAT A . G 7 HOH 138 1943 138 HOH WAT A . G 7 HOH 139 1944 139 HOH WAT A . G 7 HOH 140 1945 140 HOH WAT A . G 7 HOH 141 1946 141 HOH WAT A . G 7 HOH 142 1947 142 HOH WAT A . G 7 HOH 143 1948 143 HOH WAT A . G 7 HOH 144 1949 144 HOH WAT A . G 7 HOH 145 1950 145 HOH WAT A . G 7 HOH 146 1951 146 HOH WAT A . G 7 HOH 147 1952 147 HOH WAT A . G 7 HOH 148 1953 148 HOH WAT A . G 7 HOH 149 1954 149 HOH WAT A . G 7 HOH 150 1955 150 HOH WAT A . G 7 HOH 151 1956 151 HOH WAT A . G 7 HOH 152 1957 152 HOH WAT A . G 7 HOH 153 1958 153 HOH WAT A . G 7 HOH 154 1959 154 HOH WAT A . G 7 HOH 155 1960 155 HOH WAT A . G 7 HOH 156 1961 156 HOH WAT A . G 7 HOH 157 1962 157 HOH WAT A . G 7 HOH 158 1963 158 HOH WAT A . G 7 HOH 159 1964 159 HOH WAT A . G 7 HOH 160 1965 160 HOH WAT A . G 7 HOH 161 1966 161 HOH WAT A . G 7 HOH 162 1967 162 HOH WAT A . G 7 HOH 163 1968 163 HOH WAT A . G 7 HOH 164 1969 164 HOH WAT A . G 7 HOH 165 1970 165 HOH WAT A . G 7 HOH 166 1971 166 HOH WAT A . G 7 HOH 167 1972 167 HOH WAT A . G 7 HOH 168 1973 168 HOH WAT A . G 7 HOH 169 1974 169 HOH WAT A . G 7 HOH 170 1975 170 HOH WAT A . G 7 HOH 171 1976 171 HOH WAT A . G 7 HOH 172 1977 172 HOH WAT A . G 7 HOH 173 1978 173 HOH WAT A . G 7 HOH 174 1979 174 HOH WAT A . G 7 HOH 175 1980 175 HOH WAT A . G 7 HOH 176 1981 176 HOH WAT A . G 7 HOH 177 1982 177 HOH WAT A . G 7 HOH 178 1983 178 HOH WAT A . G 7 HOH 179 1984 179 HOH WAT A . G 7 HOH 180 1985 180 HOH WAT A . G 7 HOH 181 1986 181 HOH WAT A . G 7 HOH 182 1987 182 HOH WAT A . G 7 HOH 183 1988 183 HOH WAT A . G 7 HOH 184 1989 184 HOH WAT A . G 7 HOH 185 1990 185 HOH WAT A . G 7 HOH 186 1991 186 HOH WAT A . G 7 HOH 187 1992 187 HOH WAT A . G 7 HOH 188 1993 188 HOH WAT A . G 7 HOH 189 1994 189 HOH WAT A . G 7 HOH 190 1995 190 HOH WAT A . G 7 HOH 191 1996 191 HOH WAT A . G 7 HOH 192 1997 192 HOH WAT A . G 7 HOH 193 1998 193 HOH WAT A . G 7 HOH 194 1999 194 HOH WAT A . G 7 HOH 195 2000 195 HOH WAT A . G 7 HOH 196 2001 196 HOH WAT A . G 7 HOH 197 2002 197 HOH WAT A . G 7 HOH 198 2003 198 HOH WAT A . G 7 HOH 199 2004 199 HOH WAT A . G 7 HOH 200 2005 200 HOH WAT A . G 7 HOH 201 2006 201 HOH WAT A . G 7 HOH 202 2007 202 HOH WAT A . G 7 HOH 203 2008 203 HOH WAT A . G 7 HOH 204 2009 204 HOH WAT A . G 7 HOH 205 2010 205 HOH WAT A . G 7 HOH 206 2011 206 HOH WAT A . G 7 HOH 207 2012 207 HOH WAT A . G 7 HOH 208 2013 208 HOH WAT A . G 7 HOH 209 2014 209 HOH WAT A . G 7 HOH 210 2015 210 HOH WAT A . G 7 HOH 211 2016 211 HOH WAT A . G 7 HOH 212 2017 212 HOH WAT A . G 7 HOH 213 2018 213 HOH WAT A . G 7 HOH 214 2019 214 HOH WAT A . G 7 HOH 215 2020 215 HOH WAT A . G 7 HOH 216 2021 216 HOH WAT A . G 7 HOH 217 2022 217 HOH WAT A . G 7 HOH 218 2023 218 HOH WAT A . G 7 HOH 219 2024 219 HOH WAT A . G 7 HOH 220 2025 220 HOH WAT A . G 7 HOH 221 2026 221 HOH WAT A . G 7 HOH 222 2027 222 HOH WAT A . G 7 HOH 223 2028 223 HOH WAT A . G 7 HOH 224 2029 224 HOH WAT A . G 7 HOH 225 2030 225 HOH WAT A . G 7 HOH 226 2031 226 HOH WAT A . G 7 HOH 227 2032 227 HOH WAT A . G 7 HOH 228 2033 228 HOH WAT A . G 7 HOH 229 2034 229 HOH WAT A . G 7 HOH 230 2035 230 HOH WAT A . G 7 HOH 231 2036 231 HOH WAT A . G 7 HOH 232 2037 232 HOH WAT A . G 7 HOH 233 2038 233 HOH WAT A . G 7 HOH 234 2039 234 HOH WAT A . G 7 HOH 235 2040 235 HOH WAT A . G 7 HOH 236 2041 236 HOH WAT A . G 7 HOH 237 2042 237 HOH WAT A . G 7 HOH 238 2043 238 HOH WAT A . G 7 HOH 239 2044 239 HOH WAT A . G 7 HOH 240 2045 240 HOH WAT A . G 7 HOH 241 2046 241 HOH WAT A . G 7 HOH 242 2047 242 HOH WAT A . G 7 HOH 243 2048 243 HOH WAT A . G 7 HOH 244 2049 244 HOH WAT A . G 7 HOH 245 2050 245 HOH WAT A . G 7 HOH 246 2051 246 HOH WAT A . G 7 HOH 247 2052 247 HOH WAT A . G 7 HOH 248 2053 248 HOH WAT A . G 7 HOH 249 2054 249 HOH WAT A . G 7 HOH 250 2055 250 HOH WAT A . G 7 HOH 251 2056 251 HOH WAT A . G 7 HOH 252 2057 252 HOH WAT A . G 7 HOH 253 2058 253 HOH WAT A . G 7 HOH 254 2059 254 HOH WAT A . G 7 HOH 255 2060 255 HOH WAT A . G 7 HOH 256 2061 256 HOH WAT A . G 7 HOH 257 2062 257 HOH WAT A . G 7 HOH 258 2063 258 HOH WAT A . G 7 HOH 259 2064 259 HOH WAT A . G 7 HOH 260 2065 260 HOH WAT A . G 7 HOH 261 2066 261 HOH WAT A . G 7 HOH 262 2067 262 HOH WAT A . G 7 HOH 263 2068 263 HOH WAT A . G 7 HOH 264 2069 264 HOH WAT A . G 7 HOH 265 2070 265 HOH WAT A . G 7 HOH 266 2071 266 HOH WAT A . G 7 HOH 267 2072 267 HOH WAT A . G 7 HOH 268 2073 268 HOH WAT A . G 7 HOH 269 2074 269 HOH WAT A . G 7 HOH 270 2075 270 HOH WAT A . G 7 HOH 271 2076 271 HOH WAT A . G 7 HOH 272 2077 272 HOH WAT A . G 7 HOH 273 2078 273 HOH WAT A . G 7 HOH 274 2079 274 HOH WAT A . G 7 HOH 275 2080 275 HOH WAT A . G 7 HOH 276 2081 276 HOH WAT A . G 7 HOH 277 2082 277 HOH WAT A . G 7 HOH 278 2083 278 HOH WAT A . G 7 HOH 279 2084 279 HOH WAT A . G 7 HOH 280 2085 280 HOH WAT A . G 7 HOH 281 2086 281 HOH WAT A . G 7 HOH 282 2087 282 HOH WAT A . G 7 HOH 283 2088 283 HOH WAT A . G 7 HOH 284 2089 284 HOH WAT A . G 7 HOH 285 2090 285 HOH WAT A . G 7 HOH 286 2091 286 HOH WAT A . G 7 HOH 287 2092 287 HOH WAT A . G 7 HOH 288 2093 288 HOH WAT A . G 7 HOH 289 2094 289 HOH WAT A . G 7 HOH 290 2095 290 HOH WAT A . G 7 HOH 291 2096 291 HOH WAT A . G 7 HOH 292 2097 292 HOH WAT A . G 7 HOH 293 2098 293 HOH WAT A . G 7 HOH 294 2099 294 HOH WAT A . G 7 HOH 295 2100 295 HOH WAT A . G 7 HOH 296 2101 296 HOH WAT A . G 7 HOH 297 2102 297 HOH WAT A . G 7 HOH 298 2103 298 HOH WAT A . G 7 HOH 299 2104 299 HOH WAT A . G 7 HOH 300 2105 300 HOH WAT A . G 7 HOH 301 2106 301 HOH WAT A . G 7 HOH 302 2107 302 HOH WAT A . G 7 HOH 303 2108 303 HOH WAT A . G 7 HOH 304 2109 304 HOH WAT A . G 7 HOH 305 2110 305 HOH WAT A . G 7 HOH 306 2111 306 HOH WAT A . G 7 HOH 307 2112 307 HOH WAT A . G 7 HOH 308 2113 308 HOH WAT A . G 7 HOH 309 2114 309 HOH WAT A . G 7 HOH 310 2115 310 HOH WAT A . G 7 HOH 311 2116 311 HOH WAT A . G 7 HOH 312 2117 312 HOH WAT A . G 7 HOH 313 2118 313 HOH WAT A . G 7 HOH 314 2119 314 HOH WAT A . G 7 HOH 315 2120 315 HOH WAT A . G 7 HOH 316 2121 316 HOH WAT A . G 7 HOH 317 2122 317 HOH WAT A . G 7 HOH 318 2123 318 HOH WAT A . G 7 HOH 319 2124 319 HOH WAT A . G 7 HOH 320 2125 320 HOH WAT A . G 7 HOH 321 2126 321 HOH WAT A . G 7 HOH 322 2127 322 HOH WAT A . G 7 HOH 323 2128 323 HOH WAT A . G 7 HOH 324 2129 324 HOH WAT A . G 7 HOH 325 2130 325 HOH WAT A . G 7 HOH 326 2131 326 HOH WAT A . G 7 HOH 327 2132 327 HOH WAT A . G 7 HOH 328 2133 328 HOH WAT A . G 7 HOH 329 2134 329 HOH WAT A . G 7 HOH 330 2135 330 HOH WAT A . G 7 HOH 331 2136 331 HOH WAT A . G 7 HOH 332 2137 332 HOH WAT A . G 7 HOH 333 2138 333 HOH WAT A . G 7 HOH 334 2139 334 HOH WAT A . G 7 HOH 335 2140 335 HOH WAT A . G 7 HOH 336 2141 336 HOH WAT A . G 7 HOH 337 2142 337 HOH WAT A . G 7 HOH 338 2143 338 HOH WAT A . G 7 HOH 339 2144 339 HOH WAT A . G 7 HOH 340 2145 340 HOH WAT A . G 7 HOH 341 2146 341 HOH WAT A . G 7 HOH 342 2147 342 HOH WAT A . G 7 HOH 343 2148 343 HOH WAT A . G 7 HOH 344 2149 344 HOH WAT A . G 7 HOH 345 2150 345 HOH WAT A . G 7 HOH 346 2151 346 HOH WAT A . G 7 HOH 347 2152 347 HOH WAT A . G 7 HOH 348 2153 348 HOH WAT A . G 7 HOH 349 2154 349 HOH WAT A . G 7 HOH 350 2155 350 HOH WAT A . G 7 HOH 351 2156 351 HOH WAT A . G 7 HOH 352 2157 352 HOH WAT A . G 7 HOH 353 2158 353 HOH WAT A . G 7 HOH 354 2159 354 HOH WAT A . G 7 HOH 355 2160 355 HOH WAT A . G 7 HOH 356 2161 356 HOH WAT A . G 7 HOH 357 2162 357 HOH WAT A . G 7 HOH 358 2163 358 HOH WAT A . G 7 HOH 359 2164 359 HOH WAT A . G 7 HOH 360 2165 360 HOH WAT A . G 7 HOH 361 2166 361 HOH WAT A . G 7 HOH 362 2167 362 HOH WAT A . G 7 HOH 363 2168 363 HOH WAT A . G 7 HOH 364 2169 364 HOH WAT A . G 7 HOH 365 2170 365 HOH WAT A . G 7 HOH 366 2171 366 HOH WAT A . G 7 HOH 367 2172 367 HOH WAT A . G 7 HOH 368 2173 368 HOH WAT A . G 7 HOH 369 2174 369 HOH WAT A . G 7 HOH 370 2175 370 HOH WAT A . G 7 HOH 371 2176 371 HOH WAT A . G 7 HOH 372 2177 372 HOH WAT A . G 7 HOH 373 2178 373 HOH WAT A . G 7 HOH 374 2179 374 HOH WAT A . G 7 HOH 375 2180 375 HOH WAT A . G 7 HOH 376 2181 376 HOH WAT A . G 7 HOH 377 2182 377 HOH WAT A . G 7 HOH 378 2183 378 HOH WAT A . G 7 HOH 379 2184 379 HOH WAT A . G 7 HOH 380 2185 380 HOH WAT A . G 7 HOH 381 2186 381 HOH WAT A . G 7 HOH 382 2187 382 HOH WAT A . G 7 HOH 383 2188 383 HOH WAT A . G 7 HOH 384 2189 384 HOH WAT A . G 7 HOH 385 2190 385 HOH WAT A . G 7 HOH 386 2191 386 HOH WAT A . G 7 HOH 387 2192 387 HOH WAT A . G 7 HOH 388 2193 388 HOH WAT A . G 7 HOH 389 2194 389 HOH WAT A . G 7 HOH 390 2195 390 HOH WAT A . G 7 HOH 391 2196 391 HOH WAT A . G 7 HOH 392 2197 392 HOH WAT A . G 7 HOH 393 2198 393 HOH WAT A . G 7 HOH 394 2199 394 HOH WAT A . G 7 HOH 395 2200 395 HOH WAT A . G 7 HOH 396 2201 396 HOH WAT A . G 7 HOH 397 2202 397 HOH WAT A . G 7 HOH 398 2203 398 HOH WAT A . G 7 HOH 399 2204 399 HOH WAT A . G 7 HOH 400 2205 400 HOH WAT A . G 7 HOH 401 2206 401 HOH WAT A . G 7 HOH 402 2207 402 HOH WAT A . G 7 HOH 403 2208 403 HOH WAT A . G 7 HOH 404 2209 404 HOH WAT A . G 7 HOH 405 2210 405 HOH WAT A . G 7 HOH 406 2211 406 HOH WAT A . G 7 HOH 407 2212 407 HOH WAT A . G 7 HOH 408 2213 408 HOH WAT A . G 7 HOH 409 2214 409 HOH WAT A . G 7 HOH 410 2215 410 HOH WAT A . G 7 HOH 411 2216 411 HOH WAT A . G 7 HOH 412 2217 412 HOH WAT A . G 7 HOH 413 2218 413 HOH WAT A . G 7 HOH 414 2219 414 HOH WAT A . G 7 HOH 415 2220 415 HOH WAT A . G 7 HOH 416 2221 416 HOH WAT A . G 7 HOH 417 2222 417 HOH WAT A . G 7 HOH 418 2223 418 HOH WAT A . G 7 HOH 419 2224 419 HOH WAT A . G 7 HOH 420 2225 420 HOH WAT A . G 7 HOH 421 2226 421 HOH WAT A . G 7 HOH 422 2227 422 HOH WAT A . G 7 HOH 423 2228 423 HOH WAT A . G 7 HOH 424 2229 424 HOH WAT A . G 7 HOH 425 2230 425 HOH WAT A . G 7 HOH 426 2231 426 HOH WAT A . G 7 HOH 427 2232 427 HOH WAT A . G 7 HOH 428 2233 428 HOH WAT A . G 7 HOH 429 2234 429 HOH WAT A . G 7 HOH 430 2235 430 HOH WAT A . G 7 HOH 431 2236 431 HOH WAT A . G 7 HOH 432 2237 432 HOH WAT A . G 7 HOH 433 2238 433 HOH WAT A . G 7 HOH 434 2239 434 HOH WAT A . G 7 HOH 435 2240 435 HOH WAT A . G 7 HOH 436 2241 436 HOH WAT A . G 7 HOH 437 2242 437 HOH WAT A . G 7 HOH 438 2243 438 HOH WAT A . G 7 HOH 439 2244 439 HOH WAT A . G 7 HOH 440 2245 440 HOH WAT A . G 7 HOH 441 2246 441 HOH WAT A . G 7 HOH 442 2247 442 HOH WAT A . G 7 HOH 443 2248 443 HOH WAT A . G 7 HOH 444 2249 444 HOH WAT A . G 7 HOH 445 2250 445 HOH WAT A . G 7 HOH 446 2251 446 HOH WAT A . G 7 HOH 447 2252 447 HOH WAT A . G 7 HOH 448 2253 448 HOH WAT A . G 7 HOH 449 2254 449 HOH WAT A . G 7 HOH 450 2255 450 HOH WAT A . G 7 HOH 451 2256 451 HOH WAT A . G 7 HOH 452 2257 452 HOH WAT A . G 7 HOH 453 2258 453 HOH WAT A . G 7 HOH 454 2259 454 HOH WAT A . G 7 HOH 455 2260 455 HOH WAT A . G 7 HOH 456 2261 456 HOH WAT A . G 7 HOH 457 2262 457 HOH WAT A . G 7 HOH 458 2263 458 HOH WAT A . G 7 HOH 459 2264 459 HOH WAT A . G 7 HOH 460 2265 460 HOH WAT A . G 7 HOH 461 2266 461 HOH WAT A . G 7 HOH 462 2267 462 HOH WAT A . G 7 HOH 463 2268 463 HOH WAT A . G 7 HOH 464 2269 464 HOH WAT A . G 7 HOH 465 2270 465 HOH WAT A . G 7 HOH 466 2271 466 HOH WAT A . G 7 HOH 467 2272 467 HOH WAT A . G 7 HOH 468 2273 468 HOH WAT A . G 7 HOH 469 2274 469 HOH WAT A . G 7 HOH 470 2275 470 HOH WAT A . G 7 HOH 471 2276 471 HOH WAT A . G 7 HOH 472 2277 472 HOH WAT A . G 7 HOH 473 2278 473 HOH WAT A . G 7 HOH 474 2279 474 HOH WAT A . G 7 HOH 475 2280 475 HOH WAT A . G 7 HOH 476 2281 476 HOH WAT A . G 7 HOH 477 2282 477 HOH WAT A . G 7 HOH 478 2283 478 HOH WAT A . G 7 HOH 479 2284 479 HOH WAT A . G 7 HOH 480 2285 480 HOH WAT A . G 7 HOH 481 2286 481 HOH WAT A . G 7 HOH 482 2287 482 HOH WAT A . G 7 HOH 483 2288 483 HOH WAT A . G 7 HOH 484 2289 484 HOH WAT A . G 7 HOH 485 2290 485 HOH WAT A . G 7 HOH 486 2291 486 HOH WAT A . G 7 HOH 487 2292 487 HOH WAT A . G 7 HOH 488 2293 488 HOH WAT A . G 7 HOH 489 2294 489 HOH WAT A . G 7 HOH 490 2295 490 HOH WAT A . G 7 HOH 491 2296 491 HOH WAT A . G 7 HOH 492 2297 492 HOH WAT A . G 7 HOH 493 2298 493 HOH WAT A . G 7 HOH 494 2299 494 HOH WAT A . G 7 HOH 495 2300 495 HOH WAT A . G 7 HOH 496 2301 496 HOH WAT A . G 7 HOH 497 2302 497 HOH WAT A . G 7 HOH 498 2303 498 HOH WAT A . G 7 HOH 499 2304 499 HOH WAT A . G 7 HOH 500 2305 500 HOH WAT A . G 7 HOH 501 2306 501 HOH WAT A . G 7 HOH 502 2307 502 HOH WAT A . G 7 HOH 503 2308 503 HOH WAT A . G 7 HOH 504 2309 504 HOH WAT A . G 7 HOH 505 2310 505 HOH WAT A . G 7 HOH 506 2311 506 HOH WAT A . G 7 HOH 507 2312 507 HOH WAT A . G 7 HOH 508 2313 508 HOH WAT A . G 7 HOH 509 2314 509 HOH WAT A . G 7 HOH 510 2315 510 HOH WAT A . G 7 HOH 511 2316 511 HOH WAT A . G 7 HOH 512 2317 512 HOH WAT A . G 7 HOH 513 2318 513 HOH WAT A . G 7 HOH 514 2319 514 HOH WAT A . G 7 HOH 515 2320 515 HOH WAT A . G 7 HOH 516 2321 516 HOH WAT A . G 7 HOH 517 2322 517 HOH WAT A . G 7 HOH 518 2323 518 HOH WAT A . G 7 HOH 519 2324 519 HOH WAT A . G 7 HOH 520 2325 520 HOH WAT A . G 7 HOH 521 2326 521 HOH WAT A . G 7 HOH 522 2327 522 HOH WAT A . G 7 HOH 523 2328 523 HOH WAT A . G 7 HOH 524 2329 524 HOH WAT A . G 7 HOH 525 2330 525 HOH WAT A . G 7 HOH 526 2331 526 HOH WAT A . G 7 HOH 527 2332 527 HOH WAT A . G 7 HOH 528 2333 528 HOH WAT A . G 7 HOH 529 2334 529 HOH WAT A . G 7 HOH 530 2335 530 HOH WAT A . G 7 HOH 531 2336 531 HOH WAT A . G 7 HOH 532 2337 532 HOH WAT A . G 7 HOH 533 2338 533 HOH WAT A . G 7 HOH 534 2339 534 HOH WAT A . G 7 HOH 535 2340 535 HOH WAT A . G 7 HOH 536 2341 536 HOH WAT A . G 7 HOH 537 2342 537 HOH WAT A . G 7 HOH 538 2343 538 HOH WAT A . G 7 HOH 539 2344 539 HOH WAT A . G 7 HOH 540 2345 540 HOH WAT A . G 7 HOH 541 2346 541 HOH WAT A . G 7 HOH 542 2347 542 HOH WAT A . G 7 HOH 543 2348 543 HOH WAT A . G 7 HOH 544 2349 544 HOH WAT A . G 7 HOH 545 2350 545 HOH WAT A . G 7 HOH 546 2351 546 HOH WAT A . G 7 HOH 547 2352 547 HOH WAT A . G 7 HOH 548 2353 548 HOH WAT A . G 7 HOH 549 2354 549 HOH WAT A . G 7 HOH 550 2355 550 HOH WAT A . G 7 HOH 551 2356 551 HOH WAT A . G 7 HOH 552 2357 552 HOH WAT A . G 7 HOH 553 2358 553 HOH WAT A . G 7 HOH 554 2359 554 HOH WAT A . G 7 HOH 555 2360 555 HOH WAT A . G 7 HOH 556 2361 556 HOH WAT A . G 7 HOH 557 2362 557 HOH WAT A . G 7 HOH 558 2363 558 HOH WAT A . G 7 HOH 559 2364 559 HOH WAT A . G 7 HOH 560 2365 560 HOH WAT A . G 7 HOH 561 2366 561 HOH WAT A . G 7 HOH 562 2367 562 HOH WAT A . G 7 HOH 563 2368 563 HOH WAT A . G 7 HOH 564 2369 564 HOH WAT A . G 7 HOH 565 2370 565 HOH WAT A . G 7 HOH 566 2371 566 HOH WAT A . G 7 HOH 567 2372 567 HOH WAT A . G 7 HOH 568 2373 568 HOH WAT A . G 7 HOH 569 2374 569 HOH WAT A . G 7 HOH 570 2375 570 HOH WAT A . G 7 HOH 571 2376 571 HOH WAT A . G 7 HOH 572 2377 572 HOH WAT A . G 7 HOH 573 2378 573 HOH WAT A . G 7 HOH 574 2379 574 HOH WAT A . G 7 HOH 575 2380 575 HOH WAT A . G 7 HOH 576 2381 576 HOH WAT A . G 7 HOH 577 2382 577 HOH WAT A . G 7 HOH 578 2383 578 HOH WAT A . G 7 HOH 579 2384 579 HOH WAT A . G 7 HOH 580 2385 580 HOH WAT A . G 7 HOH 581 2386 581 HOH WAT A . G 7 HOH 582 2387 582 HOH WAT A . G 7 HOH 583 2388 583 HOH WAT A . G 7 HOH 584 2389 584 HOH WAT A . G 7 HOH 585 2390 585 HOH WAT A . G 7 HOH 586 2391 586 HOH WAT A . G 7 HOH 587 2392 587 HOH WAT A . G 7 HOH 588 2393 588 HOH WAT A . G 7 HOH 589 2394 589 HOH WAT A . G 7 HOH 590 2395 590 HOH WAT A . G 7 HOH 591 2396 591 HOH WAT A . G 7 HOH 592 2397 592 HOH WAT A . G 7 HOH 593 2398 593 HOH WAT A . G 7 HOH 594 2399 594 HOH WAT A . G 7 HOH 595 2400 595 HOH WAT A . G 7 HOH 596 2401 596 HOH WAT A . G 7 HOH 597 2402 597 HOH WAT A . G 7 HOH 598 2403 598 HOH WAT A . G 7 HOH 599 2404 599 HOH WAT A . G 7 HOH 600 2405 600 HOH WAT A . G 7 HOH 601 2406 601 HOH WAT A . G 7 HOH 602 2407 602 HOH WAT A . G 7 HOH 603 2408 603 HOH WAT A . G 7 HOH 604 2409 604 HOH WAT A . G 7 HOH 605 2410 605 HOH WAT A . G 7 HOH 606 2411 606 HOH WAT A . G 7 HOH 607 2412 607 HOH WAT A . G 7 HOH 608 2413 608 HOH WAT A . G 7 HOH 609 2414 609 HOH WAT A . G 7 HOH 610 2415 610 HOH WAT A . G 7 HOH 611 2416 611 HOH WAT A . G 7 HOH 612 2417 612 HOH WAT A . G 7 HOH 613 2418 613 HOH WAT A . G 7 HOH 614 2419 614 HOH WAT A . G 7 HOH 615 2420 615 HOH WAT A . G 7 HOH 616 2421 616 HOH WAT A . G 7 HOH 617 2422 617 HOH WAT A . G 7 HOH 618 2423 618 HOH WAT A . G 7 HOH 619 2424 619 HOH WAT A . G 7 HOH 620 2425 620 HOH WAT A . G 7 HOH 621 2426 621 HOH WAT A . G 7 HOH 622 2427 622 HOH WAT A . G 7 HOH 623 2428 623 HOH WAT A . G 7 HOH 624 2429 624 HOH WAT A . G 7 HOH 625 2430 625 HOH WAT A . G 7 HOH 626 2431 626 HOH WAT A . G 7 HOH 627 2432 627 HOH WAT A . G 7 HOH 628 2433 628 HOH WAT A . G 7 HOH 629 2434 629 HOH WAT A . G 7 HOH 630 2435 630 HOH WAT A . G 7 HOH 631 2436 631 HOH WAT A . G 7 HOH 632 2437 632 HOH WAT A . G 7 HOH 633 2438 633 HOH WAT A . G 7 HOH 634 2439 634 HOH WAT A . G 7 HOH 635 2440 635 HOH WAT A . G 7 HOH 636 2441 636 HOH WAT A . G 7 HOH 637 2442 637 HOH WAT A . G 7 HOH 638 2443 638 HOH WAT A . G 7 HOH 639 2444 639 HOH WAT A . G 7 HOH 640 2445 640 HOH WAT A . G 7 HOH 641 2446 641 HOH WAT A . G 7 HOH 642 2447 642 HOH WAT A . G 7 HOH 643 2448 643 HOH WAT A . G 7 HOH 644 2449 644 HOH WAT A . G 7 HOH 645 2450 645 HOH WAT A . G 7 HOH 646 2451 646 HOH WAT A . G 7 HOH 647 2452 647 HOH WAT A . G 7 HOH 648 2453 648 HOH WAT A . G 7 HOH 649 2454 649 HOH WAT A . G 7 HOH 650 2455 650 HOH WAT A . G 7 HOH 651 2456 651 HOH WAT A . G 7 HOH 652 2457 652 HOH WAT A . G 7 HOH 653 2458 653 HOH WAT A . G 7 HOH 654 2459 654 HOH WAT A . G 7 HOH 655 2460 655 HOH WAT A . G 7 HOH 656 2461 656 HOH WAT A . G 7 HOH 657 2462 657 HOH WAT A . G 7 HOH 658 2463 658 HOH WAT A . G 7 HOH 659 2464 659 HOH WAT A . G 7 HOH 660 2465 660 HOH WAT A . G 7 HOH 661 2466 661 HOH WAT A . G 7 HOH 662 2467 662 HOH WAT A . G 7 HOH 663 2468 663 HOH WAT A . G 7 HOH 664 2469 664 HOH WAT A . G 7 HOH 665 2470 665 HOH WAT A . G 7 HOH 666 2471 666 HOH WAT A . G 7 HOH 667 2472 667 HOH WAT A . G 7 HOH 668 2473 668 HOH WAT A . G 7 HOH 669 2474 669 HOH WAT A . G 7 HOH 670 2475 670 HOH WAT A . G 7 HOH 671 2476 671 HOH WAT A . G 7 HOH 672 2477 672 HOH WAT A . G 7 HOH 673 2478 673 HOH WAT A . G 7 HOH 674 2479 674 HOH WAT A . G 7 HOH 675 2480 675 HOH WAT A . G 7 HOH 676 2481 676 HOH WAT A . G 7 HOH 677 2482 677 HOH WAT A . G 7 HOH 678 2483 678 HOH WAT A . G 7 HOH 679 2484 679 HOH WAT A . G 7 HOH 680 2485 680 HOH WAT A . G 7 HOH 681 2486 681 HOH WAT A . G 7 HOH 682 2487 682 HOH WAT A . G 7 HOH 683 2488 683 HOH WAT A . G 7 HOH 684 2489 684 HOH WAT A . G 7 HOH 685 2490 685 HOH WAT A . G 7 HOH 686 2491 686 HOH WAT A . G 7 HOH 687 2492 687 HOH WAT A . G 7 HOH 688 2493 688 HOH WAT A . G 7 HOH 689 2494 689 HOH WAT A . G 7 HOH 690 2495 690 HOH WAT A . G 7 HOH 691 2496 691 HOH WAT A . G 7 HOH 692 2497 692 HOH WAT A . G 7 HOH 693 2498 693 HOH WAT A . G 7 HOH 694 2499 694 HOH WAT A . G 7 HOH 695 2500 695 HOH WAT A . G 7 HOH 696 2501 696 HOH WAT A . G 7 HOH 697 2502 697 HOH WAT A . G 7 HOH 698 2503 698 HOH WAT A . G 7 HOH 699 2504 699 HOH WAT A . G 7 HOH 700 2505 700 HOH WAT A . G 7 HOH 701 2506 701 HOH WAT A . G 7 HOH 702 2507 702 HOH WAT A . G 7 HOH 703 2508 703 HOH WAT A . G 7 HOH 704 2509 704 HOH WAT A . G 7 HOH 705 2510 705 HOH WAT A . G 7 HOH 706 2511 706 HOH WAT A . G 7 HOH 707 2512 707 HOH WAT A . G 7 HOH 708 2513 708 HOH WAT A . G 7 HOH 709 2514 709 HOH WAT A . G 7 HOH 710 2515 710 HOH WAT A . G 7 HOH 711 2516 711 HOH WAT A . G 7 HOH 712 2517 712 HOH WAT A . G 7 HOH 713 2518 713 HOH WAT A . G 7 HOH 714 2519 714 HOH WAT A . G 7 HOH 715 2520 715 HOH WAT A . G 7 HOH 716 2521 716 HOH WAT A . G 7 HOH 717 2522 717 HOH WAT A . G 7 HOH 718 2523 718 HOH WAT A . G 7 HOH 719 2524 719 HOH WAT A . G 7 HOH 720 2525 720 HOH WAT A . G 7 HOH 721 2526 721 HOH WAT A . G 7 HOH 722 2527 722 HOH WAT A . G 7 HOH 723 2528 723 HOH WAT A . G 7 HOH 724 2529 724 HOH WAT A . G 7 HOH 725 2530 725 HOH WAT A . G 7 HOH 726 2531 726 HOH WAT A . G 7 HOH 727 2532 727 HOH WAT A . G 7 HOH 728 2533 728 HOH WAT A . G 7 HOH 729 2534 729 HOH WAT A . G 7 HOH 730 2535 730 HOH WAT A . G 7 HOH 731 2536 731 HOH WAT A . G 7 HOH 732 2537 732 HOH WAT A . G 7 HOH 733 2538 733 HOH WAT A . G 7 HOH 734 2539 734 HOH WAT A . G 7 HOH 735 2540 735 HOH WAT A . G 7 HOH 736 2541 736 HOH WAT A . G 7 HOH 737 2542 737 HOH WAT A . G 7 HOH 738 2543 738 HOH WAT A . G 7 HOH 739 2544 739 HOH WAT A . G 7 HOH 740 2545 740 HOH WAT A . G 7 HOH 741 2546 741 HOH WAT A . G 7 HOH 742 2547 742 HOH WAT A . G 7 HOH 743 2548 743 HOH WAT A . G 7 HOH 744 2549 744 HOH WAT A . G 7 HOH 745 2550 745 HOH WAT A . G 7 HOH 746 2551 746 HOH WAT A . G 7 HOH 747 2552 747 HOH WAT A . G 7 HOH 748 2553 748 HOH WAT A . G 7 HOH 749 2554 749 HOH WAT A . G 7 HOH 750 2555 750 HOH WAT A . G 7 HOH 751 2556 751 HOH WAT A . G 7 HOH 752 2557 752 HOH WAT A . G 7 HOH 753 2558 753 HOH WAT A . G 7 HOH 754 2559 754 HOH WAT A . G 7 HOH 755 2560 755 HOH WAT A . G 7 HOH 756 2561 756 HOH WAT A . G 7 HOH 757 2562 757 HOH WAT A . G 7 HOH 758 2563 758 HOH WAT A . G 7 HOH 759 2564 759 HOH WAT A . G 7 HOH 760 2565 760 HOH WAT A . G 7 HOH 761 2566 761 HOH WAT A . G 7 HOH 762 2567 762 HOH WAT A . G 7 HOH 763 2568 763 HOH WAT A . G 7 HOH 764 2569 764 HOH WAT A . G 7 HOH 765 2570 765 HOH WAT A . G 7 HOH 766 2571 766 HOH WAT A . G 7 HOH 767 2572 767 HOH WAT A . G 7 HOH 768 2573 768 HOH WAT A . G 7 HOH 769 2574 769 HOH WAT A . G 7 HOH 770 2575 770 HOH WAT A . G 7 HOH 771 2576 771 HOH WAT A . G 7 HOH 772 2577 772 HOH WAT A . G 7 HOH 773 2578 773 HOH WAT A . G 7 HOH 774 2579 774 HOH WAT A . G 7 HOH 775 2580 775 HOH WAT A . G 7 HOH 776 2581 776 HOH WAT A . G 7 HOH 777 2582 777 HOH WAT A . G 7 HOH 778 2583 778 HOH WAT A . G 7 HOH 779 2584 779 HOH WAT A . G 7 HOH 780 2585 780 HOH WAT A . G 7 HOH 781 2586 781 HOH WAT A . G 7 HOH 782 2587 782 HOH WAT A . G 7 HOH 783 2588 783 HOH WAT A . G 7 HOH 784 2589 784 HOH WAT A . G 7 HOH 785 2590 785 HOH WAT A . G 7 HOH 786 2591 786 HOH WAT A . G 7 HOH 787 2592 787 HOH WAT A . G 7 HOH 788 2593 788 HOH WAT A . G 7 HOH 789 2594 789 HOH WAT A . G 7 HOH 790 2595 790 HOH WAT A . G 7 HOH 791 2596 791 HOH WAT A . G 7 HOH 792 2597 792 HOH WAT A . G 7 HOH 793 2598 793 HOH WAT A . G 7 HOH 794 2599 794 HOH WAT A . G 7 HOH 795 2600 795 HOH WAT A . G 7 HOH 796 2601 796 HOH WAT A . G 7 HOH 797 2602 797 HOH WAT A . G 7 HOH 798 2603 798 HOH WAT A . G 7 HOH 799 2604 799 HOH WAT A . G 7 HOH 800 2605 800 HOH WAT A . G 7 HOH 801 2606 801 HOH WAT A . G 7 HOH 802 2607 802 HOH WAT A . G 7 HOH 803 2608 803 HOH WAT A . G 7 HOH 804 2609 804 HOH WAT A . G 7 HOH 805 2610 805 HOH WAT A . G 7 HOH 806 2611 806 HOH WAT A . G 7 HOH 807 2612 807 HOH WAT A . G 7 HOH 808 2613 808 HOH WAT A . G 7 HOH 809 2614 809 HOH WAT A . G 7 HOH 810 2615 810 HOH WAT A . G 7 HOH 811 2616 811 HOH WAT A . G 7 HOH 812 2617 812 HOH WAT A . G 7 HOH 813 2618 813 HOH WAT A . G 7 HOH 814 2619 814 HOH WAT A . G 7 HOH 815 2620 815 HOH WAT A . G 7 HOH 816 2621 816 HOH WAT A . G 7 HOH 817 2622 817 HOH WAT A . G 7 HOH 818 2623 818 HOH WAT A . G 7 HOH 819 2624 819 HOH WAT A . G 7 HOH 820 2625 820 HOH WAT A . G 7 HOH 821 2626 821 HOH WAT A . G 7 HOH 822 2627 822 HOH WAT A . G 7 HOH 823 2628 823 HOH WAT A . G 7 HOH 824 2629 824 HOH WAT A . G 7 HOH 825 2630 825 HOH WAT A . G 7 HOH 826 2631 826 HOH WAT A . G 7 HOH 827 2632 827 HOH WAT A . G 7 HOH 828 2633 828 HOH WAT A . G 7 HOH 829 2634 829 HOH WAT A . G 7 HOH 830 2635 830 HOH WAT A . G 7 HOH 831 2636 831 HOH WAT A . G 7 HOH 832 2637 832 HOH WAT A . G 7 HOH 833 2638 833 HOH WAT A . G 7 HOH 834 2639 834 HOH WAT A . G 7 HOH 835 2640 835 HOH WAT A . G 7 HOH 836 2641 836 HOH WAT A . G 7 HOH 837 2642 837 HOH WAT A . G 7 HOH 838 2643 838 HOH WAT A . G 7 HOH 839 2644 839 HOH WAT A . G 7 HOH 840 2645 840 HOH WAT A . G 7 HOH 841 2646 841 HOH WAT A . G 7 HOH 842 2647 842 HOH WAT A . G 7 HOH 843 2648 843 HOH WAT A . G 7 HOH 844 2649 844 HOH WAT A . G 7 HOH 845 2650 845 HOH WAT A . G 7 HOH 846 2651 846 HOH WAT A . G 7 HOH 847 2652 847 HOH WAT A . G 7 HOH 848 2653 848 HOH WAT A . G 7 HOH 849 2654 849 HOH WAT A . G 7 HOH 850 2655 850 HOH WAT A . G 7 HOH 851 2656 851 HOH WAT A . G 7 HOH 852 2657 852 HOH WAT A . G 7 HOH 853 2658 853 HOH WAT A . G 7 HOH 854 2659 854 HOH WAT A . G 7 HOH 855 2660 855 HOH WAT A . G 7 HOH 856 2661 856 HOH WAT A . G 7 HOH 857 2662 857 HOH WAT A . G 7 HOH 858 2663 858 HOH WAT A . G 7 HOH 859 2664 859 HOH WAT A . G 7 HOH 860 2665 860 HOH WAT A . G 7 HOH 861 2666 861 HOH WAT A . G 7 HOH 862 2667 862 HOH WAT A . G 7 HOH 863 2668 863 HOH WAT A . G 7 HOH 864 2669 864 HOH WAT A . G 7 HOH 865 2670 865 HOH WAT A . G 7 HOH 866 2671 866 HOH WAT A . G 7 HOH 867 2672 867 HOH WAT A . G 7 HOH 868 2673 868 HOH WAT A . G 7 HOH 869 2674 869 HOH WAT A . G 7 HOH 870 2675 870 HOH WAT A . G 7 HOH 871 2676 871 HOH WAT A . G 7 HOH 872 2677 872 HOH WAT A . G 7 HOH 873 2678 873 HOH WAT A . G 7 HOH 874 2679 874 HOH WAT A . G 7 HOH 875 2680 875 HOH WAT A . G 7 HOH 876 2681 876 HOH WAT A . G 7 HOH 877 2682 877 HOH WAT A . G 7 HOH 878 2683 878 HOH WAT A . G 7 HOH 879 2684 879 HOH WAT A . G 7 HOH 880 2685 880 HOH WAT A . G 7 HOH 881 2686 881 HOH WAT A . G 7 HOH 882 2687 882 HOH WAT A . G 7 HOH 883 2688 883 HOH WAT A . G 7 HOH 884 2689 884 HOH WAT A . G 7 HOH 885 2690 885 HOH WAT A . G 7 HOH 886 2691 886 HOH WAT A . G 7 HOH 887 2692 887 HOH WAT A . G 7 HOH 888 2693 888 HOH WAT A . G 7 HOH 889 2694 889 HOH WAT A . G 7 HOH 890 2695 890 HOH WAT A . G 7 HOH 891 2696 891 HOH WAT A . G 7 HOH 892 2697 892 HOH WAT A . G 7 HOH 893 2698 893 HOH WAT A . G 7 HOH 894 2699 894 HOH WAT A . G 7 HOH 895 2700 895 HOH WAT A . G 7 HOH 896 2701 896 HOH WAT A . G 7 HOH 897 2702 897 HOH WAT A . G 7 HOH 898 2703 898 HOH WAT A . G 7 HOH 899 2704 899 HOH WAT A . G 7 HOH 900 2705 900 HOH WAT A . G 7 HOH 901 2706 901 HOH WAT A . G 7 HOH 902 2707 902 HOH WAT A . G 7 HOH 903 2708 903 HOH WAT A . G 7 HOH 904 2709 904 HOH WAT A . G 7 HOH 905 2710 905 HOH WAT A . G 7 HOH 906 2711 906 HOH WAT A . G 7 HOH 907 2712 907 HOH WAT A . G 7 HOH 908 2713 908 HOH WAT A . G 7 HOH 909 2714 909 HOH WAT A . G 7 HOH 910 2715 910 HOH WAT A . G 7 HOH 911 2716 911 HOH WAT A . G 7 HOH 912 2717 912 HOH WAT A . G 7 HOH 913 2718 913 HOH WAT A . G 7 HOH 914 2719 914 HOH WAT A . G 7 HOH 915 2720 915 HOH WAT A . G 7 HOH 916 2721 916 HOH WAT A . G 7 HOH 917 2722 917 HOH WAT A . G 7 HOH 918 2723 918 HOH WAT A . G 7 HOH 919 2724 919 HOH WAT A . G 7 HOH 920 2725 920 HOH WAT A . G 7 HOH 921 2726 921 HOH WAT A . G 7 HOH 922 2727 922 HOH WAT A . G 7 HOH 923 2728 923 HOH WAT A . G 7 HOH 924 2729 924 HOH WAT A . G 7 HOH 925 2730 925 HOH WAT A . G 7 HOH 926 2731 926 HOH WAT A . G 7 HOH 927 2732 927 HOH WAT A . G 7 HOH 928 2733 928 HOH WAT A . G 7 HOH 929 2734 929 HOH WAT A . G 7 HOH 930 2735 930 HOH WAT A . G 7 HOH 931 2736 931 HOH WAT A . G 7 HOH 932 2737 932 HOH WAT A . G 7 HOH 933 2738 933 HOH WAT A . G 7 HOH 934 2739 934 HOH WAT A . G 7 HOH 935 2740 935 HOH WAT A . G 7 HOH 936 2741 936 HOH WAT A . G 7 HOH 937 2742 937 HOH WAT A . G 7 HOH 938 2743 938 HOH WAT A . G 7 HOH 939 2744 939 HOH WAT A . G 7 HOH 940 2745 940 HOH WAT A . G 7 HOH 941 2746 941 HOH WAT A . G 7 HOH 942 2747 942 HOH WAT A . G 7 HOH 943 2748 943 HOH WAT A . G 7 HOH 944 2749 944 HOH WAT A . G 7 HOH 945 2750 945 HOH WAT A . G 7 HOH 946 2751 946 HOH WAT A . G 7 HOH 947 2752 947 HOH WAT A . G 7 HOH 948 2753 948 HOH WAT A . G 7 HOH 949 2754 949 HOH WAT A . G 7 HOH 950 2755 950 HOH WAT A . G 7 HOH 951 2756 951 HOH WAT A . G 7 HOH 952 2757 952 HOH WAT A . G 7 HOH 953 2758 953 HOH WAT A . G 7 HOH 954 2759 954 HOH WAT A . G 7 HOH 955 2760 955 HOH WAT A . G 7 HOH 956 2761 956 HOH WAT A . G 7 HOH 957 2762 957 HOH WAT A . G 7 HOH 958 2763 958 HOH WAT A . G 7 HOH 959 2764 959 HOH WAT A . G 7 HOH 960 2765 960 HOH WAT A . G 7 HOH 961 2766 961 HOH WAT A . G 7 HOH 962 2767 962 HOH WAT A . G 7 HOH 963 2768 963 HOH WAT A . G 7 HOH 964 2769 964 HOH WAT A . G 7 HOH 965 2770 965 HOH WAT A . G 7 HOH 966 2771 966 HOH WAT A . G 7 HOH 967 2772 967 HOH WAT A . G 7 HOH 968 2773 968 HOH WAT A . G 7 HOH 969 2774 969 HOH WAT A . G 7 HOH 970 2775 970 HOH WAT A . G 7 HOH 971 2776 971 HOH WAT A . G 7 HOH 972 2777 972 HOH WAT A . G 7 HOH 973 2778 973 HOH WAT A . G 7 HOH 974 2779 974 HOH WAT A . G 7 HOH 975 2780 975 HOH WAT A . G 7 HOH 976 2781 976 HOH WAT A . G 7 HOH 977 2782 977 HOH WAT A . G 7 HOH 978 2783 978 HOH WAT A . G 7 HOH 979 2784 979 HOH WAT A . G 7 HOH 980 2785 980 HOH WAT A . G 7 HOH 981 2786 981 HOH WAT A . G 7 HOH 982 2787 982 HOH WAT A . G 7 HOH 983 2788 983 HOH WAT A . G 7 HOH 984 2789 984 HOH WAT A . G 7 HOH 985 2790 985 HOH WAT A . G 7 HOH 986 2791 986 HOH WAT A . G 7 HOH 987 2792 987 HOH WAT A . G 7 HOH 988 2793 988 HOH WAT A . G 7 HOH 989 2794 989 HOH WAT A . G 7 HOH 990 2795 990 HOH WAT A . G 7 HOH 991 2796 991 HOH WAT A . G 7 HOH 992 2797 992 HOH WAT A . G 7 HOH 993 2798 993 HOH WAT A . G 7 HOH 994 2799 994 HOH WAT A . G 7 HOH 995 2800 995 HOH WAT A . G 7 HOH 996 2801 996 HOH WAT A . G 7 HOH 997 2802 997 HOH WAT A . G 7 HOH 998 2803 998 HOH WAT A . G 7 HOH 999 2804 999 HOH WAT A . G 7 HOH 1000 2805 1000 HOH WAT A . G 7 HOH 1001 2806 1001 HOH WAT A . G 7 HOH 1002 2807 1002 HOH WAT A . G 7 HOH 1003 2808 1003 HOH WAT A . G 7 HOH 1004 2809 1004 HOH WAT A . G 7 HOH 1005 2810 1005 HOH WAT A . G 7 HOH 1006 2811 1006 HOH WAT A . G 7 HOH 1007 2812 1007 HOH WAT A . G 7 HOH 1008 2813 1008 HOH WAT A . G 7 HOH 1009 2814 1009 HOH WAT A . G 7 HOH 1010 2815 1010 HOH WAT A . G 7 HOH 1011 2816 1011 HOH WAT A . G 7 HOH 1012 2817 1012 HOH WAT A . G 7 HOH 1013 2818 1013 HOH WAT A . G 7 HOH 1014 2819 1014 HOH WAT A . G 7 HOH 1015 2820 1015 HOH WAT A . G 7 HOH 1016 2821 1016 HOH WAT A . G 7 HOH 1017 2822 1017 HOH WAT A . G 7 HOH 1018 2823 1018 HOH WAT A . G 7 HOH 1019 2824 1019 HOH WAT A . G 7 HOH 1020 2825 1020 HOH WAT A . G 7 HOH 1021 2826 1021 HOH WAT A . G 7 HOH 1022 2827 1022 HOH WAT A . G 7 HOH 1023 2828 1023 HOH WAT A . G 7 HOH 1024 2829 1024 HOH WAT A . G 7 HOH 1025 2830 1025 HOH WAT A . G 7 HOH 1026 2831 1026 HOH WAT A . G 7 HOH 1027 2832 1027 HOH WAT A . G 7 HOH 1028 2833 1028 HOH WAT A . G 7 HOH 1029 2834 1029 HOH WAT A . G 7 HOH 1030 2835 1030 HOH WAT A . G 7 HOH 1031 2836 1031 HOH WAT A . G 7 HOH 1032 2837 1032 HOH WAT A . G 7 HOH 1033 2838 1033 HOH WAT A . G 7 HOH 1034 2839 1034 HOH WAT A . G 7 HOH 1035 2840 1035 HOH WAT A . G 7 HOH 1036 2841 1036 HOH WAT A . G 7 HOH 1037 2842 1037 HOH WAT A . G 7 HOH 1038 2843 1038 HOH WAT A . G 7 HOH 1039 2844 1039 HOH WAT A . G 7 HOH 1040 2845 1040 HOH WAT A . G 7 HOH 1041 2846 1041 HOH WAT A . G 7 HOH 1042 2847 1042 HOH WAT A . G 7 HOH 1043 2848 1043 HOH WAT A . G 7 HOH 1044 2849 1044 HOH WAT A . G 7 HOH 1045 2850 1045 HOH WAT A . G 7 HOH 1046 2851 1046 HOH WAT A . G 7 HOH 1047 2852 1047 HOH WAT A . G 7 HOH 1048 2853 1048 HOH WAT A . G 7 HOH 1049 2854 1049 HOH WAT A . G 7 HOH 1050 2855 1050 HOH WAT A . G 7 HOH 1051 2856 1051 HOH WAT A . G 7 HOH 1052 2857 1052 HOH WAT A . G 7 HOH 1053 2858 1053 HOH WAT A . G 7 HOH 1054 2859 1054 HOH WAT A . G 7 HOH 1055 2860 1055 HOH WAT A . G 7 HOH 1056 2861 1056 HOH WAT A . G 7 HOH 1057 2862 1057 HOH WAT A . G 7 HOH 1058 2863 1058 HOH WAT A . G 7 HOH 1059 2864 1059 HOH WAT A . G 7 HOH 1060 2865 1060 HOH WAT A . G 7 HOH 1061 2866 1061 HOH WAT A . G 7 HOH 1062 2867 1062 HOH WAT A . G 7 HOH 1063 2868 1063 HOH WAT A . G 7 HOH 1064 2869 1064 HOH WAT A . G 7 HOH 1065 2870 1065 HOH WAT A . G 7 HOH 1066 2871 1066 HOH WAT A . G 7 HOH 1067 2872 1067 HOH WAT A . G 7 HOH 1068 2873 1068 HOH WAT A . G 7 HOH 1069 2874 1069 HOH WAT A . G 7 HOH 1070 2875 1070 HOH WAT A . G 7 HOH 1071 2876 1071 HOH WAT A . G 7 HOH 1072 2877 1072 HOH WAT A . G 7 HOH 1073 2878 1073 HOH WAT A . G 7 HOH 1074 2879 1074 HOH WAT A . G 7 HOH 1075 2880 1075 HOH WAT A . G 7 HOH 1076 2881 1076 HOH WAT A . G 7 HOH 1077 2882 1077 HOH WAT A . G 7 HOH 1078 2883 1078 HOH WAT A . G 7 HOH 1079 2884 1079 HOH WAT A . G 7 HOH 1080 2885 1080 HOH WAT A . G 7 HOH 1081 2886 1081 HOH WAT A . G 7 HOH 1082 2887 1082 HOH WAT A . G 7 HOH 1083 2888 1083 HOH WAT A . G 7 HOH 1084 2889 1084 HOH WAT A . G 7 HOH 1085 2890 1085 HOH WAT A . G 7 HOH 1086 2891 1086 HOH WAT A . G 7 HOH 1087 2892 1087 HOH WAT A . G 7 HOH 1088 2893 1088 HOH WAT A . G 7 HOH 1089 2894 1089 HOH WAT A . G 7 HOH 1090 2895 1090 HOH WAT A . G 7 HOH 1091 2896 1091 HOH WAT A . G 7 HOH 1092 2897 1092 HOH WAT A . G 7 HOH 1093 2898 1093 HOH WAT A . G 7 HOH 1094 2899 1094 HOH WAT A . G 7 HOH 1095 2900 1095 HOH WAT A . G 7 HOH 1096 2901 1096 HOH WAT A . G 7 HOH 1097 2902 1097 HOH WAT A . G 7 HOH 1098 2903 1098 HOH WAT A . G 7 HOH 1099 2904 1099 HOH WAT A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 93.2 ? 2 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 96.8 ? 3 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 168.1 ? 4 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 104.7 ? 5 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 91.7 ? 6 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 92.1 ? 7 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB2 . ? A GB2 1804 ? 1_555 162.5 ? 8 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB2 . ? A GB2 1804 ? 1_555 86.5 ? 9 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB2 . ? A GB2 1804 ? 1_555 82.1 ? 10 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB2 . ? A GB2 1804 ? 1_555 92.8 ? 11 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB2 . ? A GB2 1804 ? 1_555 90.3 ? 12 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB2 . ? A GB2 1804 ? 1_555 89.8 ? 13 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB2 . ? A GB2 1804 ? 1_555 83.7 ? 14 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB2 . ? A GB2 1804 ? 1_555 164.8 ? 15 O3 ? E GB2 . ? A GB2 1804 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB2 . ? A GB2 1804 ? 1_555 72.2 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2006-12-05 2 'Structure model' 1 1 2007-10-16 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.1 ? 1 HKL-2000 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 CNS phasing . ? 4 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 CG A GLN 97 ? ? CD A GLN 97 ? B 1.677 1.506 0.171 0.023 N 2 1 CA A SER 411 ? ? CB A SER 411 ? B 1.707 1.525 0.182 0.015 N 3 1 CB A ARG 770 ? ? CG A ARG 770 ? B 1.319 1.521 -0.202 0.027 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CB A ASP 204 ? ? CG A ASP 204 ? ? OD1 A ASP 204 ? ? 123.77 118.30 5.47 0.90 N 2 1 NE A ARG 818 ? B CZ A ARG 818 ? B NH2 A ARG 818 ? B 117.27 120.30 -3.03 0.50 N 3 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH1 A ARG 963 ? ? 123.61 120.30 3.31 0.50 N 4 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH2 A ARG 963 ? ? 117.09 120.30 -3.21 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 56 ? ? -103.63 78.55 2 1 TRP A 95 ? ? -172.00 -86.15 3 1 ASP A 106 ? ? -131.62 -58.11 4 1 THR A 162 ? ? 68.54 -64.05 5 1 GLN A 227 ? ? -137.57 -45.99 6 1 ASP A 340 ? ? -170.66 -170.61 7 1 LYS A 345 ? ? -92.62 -71.52 8 1 SER A 411 ? ? 40.53 -122.07 9 1 TRP A 415 ? ? -90.32 58.07 10 1 HIS A 471 ? ? -69.76 4.53 11 1 ILE A 549 ? ? -148.69 -47.26 12 1 LEU A 550 ? ? -165.95 116.03 13 1 PRO A 562 ? ? -80.62 38.61 14 1 SER A 703 ? ? -42.70 158.17 15 1 ASN A 732 ? ? -97.04 56.63 16 1 SER A 762 ? ? 71.36 -3.25 17 1 ILE A 831 ? ? -118.10 77.59 18 1 SER A 833 ? ? -153.13 -13.45 19 1 ASP A 839 ? ? -128.08 -162.11 20 1 PRO A 990 ? ? -39.17 -79.51 21 1 GLU A 991 ? ? 55.41 94.17 22 1 GLU A 992 ? ? -134.40 -139.38 23 1 HIS A 993 ? ? 33.34 72.50 # loop_ _pdbx_validate_main_chain_plane.id _pdbx_validate_main_chain_plane.PDB_model_num _pdbx_validate_main_chain_plane.auth_comp_id _pdbx_validate_main_chain_plane.auth_asym_id _pdbx_validate_main_chain_plane.auth_seq_id _pdbx_validate_main_chain_plane.PDB_ins_code _pdbx_validate_main_chain_plane.label_alt_id _pdbx_validate_main_chain_plane.improper_torsion_angle 1 1 TYR A 75 ? B 12.77 2 1 HIS A 709 ? B 10.62 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C4 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id MPD _pdbx_validate_chiral.auth_seq_id 1801 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'PHOSPHATE ION' PO4 4 'ZINC ION' ZN 5 '(2R,3R,4S)-2-({[(1S)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' GB2 6 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 7 water HOH #